uniprotkb:Q9H756	uniprotkb:Q72C43	intact:EBI-59037180|ensembl:ENSP00000369395.5|uniprotkb:A0AV00|uniprotkb:B9EG91	intact:EBI-10090056	psi-mi:lrc19_human(display_long)|uniprotkb:LRRC19(gene name)|psi-mi:LRRC19(display_short)	psi-mi:q72c43_nitv2(display_long)|uniprotkb:DVU_1441(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Xie et al. (2024)	pubmed:38172943|imex:IM-30133	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:882(desvh)|taxid:882(""Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59037202	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000184434.8(gene)|ensembl:ENST00000380055.6(transcript)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0005886""(plasma membrane)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0048874""(host-mediated regulation of intestinal microbiota composition)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|panther:PTHR31450(orthology-group)|refseq:NP_075052.1"	"interpro:IPR046358|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|refseq:YP_010660.1|interpro:IPR042187|refseq:WP_010938734.1|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009288""(bacterial-type flagellum)"	-	-	-	figure legend:4c|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-5(molar)	2024/10/04	2024/11/14	rogid:HiSkNIG5tcH3wrx8gyoxXSve3sA9606	rogid:UCl1QnRslU8qgMo3h/QmxNPhMfs882	intact-crc:44E95772D67FA9AF|rigid:piYJ5cOWsa1L1lMwebwicRALdFg	false	his tag:c-c|glutathione s tranferase tag:n-n	his tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H756	uniprotkb:Q72C43	intact:EBI-59037180|ensembl:ENSP00000369395.5|uniprotkb:A0AV00|uniprotkb:B9EG91	intact:EBI-10090056	psi-mi:lrc19_human(display_long)|uniprotkb:LRRC19(gene name)|psi-mi:LRRC19(display_short)	psi-mi:q72c43_nitv2(display_long)|uniprotkb:DVU_1441(locus name)	"psi-mi:""MI:1247""(microscale thermophoresis)"	Xie et al. (2024)	pubmed:38172943|imex:IM-30133	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:882(desvh)|taxid:882(""Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59037354	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000184434.8(gene)|ensembl:ENST00000380055.6(transcript)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0005886""(plasma membrane)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0048874""(host-mediated regulation of intestinal microbiota composition)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|panther:PTHR31450(orthology-group)|refseq:NP_075052.1"	"interpro:IPR046358|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|refseq:YP_010660.1|interpro:IPR042187|refseq:WP_010938734.1|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009288""(bacterial-type flagellum)"	-	-	-	"figure legend:4D, 7d|antagonist:""\""Typhaneoside (CHEBI:191968)\""""|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease"	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.05x10^-6(molar)	2024/10/04	2024/11/14	rogid:HiSkNIG5tcH3wrx8gyoxXSve3sA9606	rogid:UCl1QnRslU8qgMo3h/QmxNPhMfs882	intact-crc:D98CAA670122A7AE|rigid:piYJ5cOWsa1L1lMwebwicRALdFg	false	his tag:c-c|glutathione s tranferase tag:n-n	his tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-59039400	uniprotkb:O43707	uniparc:UPI0002A1D4FE	intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|uniprotkb:A4K467|ensembl:ENSP00000252699.2|ensembl:ENSP00000489220.1	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039443	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	genbank identifier:EKX94456(see-also)	"efo:""Orphanet:656""|ensembl:ENSG00000130402.14(gene)|ensembl:ENSG00000282844.2(gene)|ensembl:ENST00000252699.7(transcript)|ensembl:ENST00000634960.2(transcript)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001725""(stress fiber)|go:""GO:0001882""(nucleoside binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030050""(vesicle transport along actin filament)|go:""GO:0030054""(cell junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031143""(pseudopodium)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032417""(""positive regulation of sodium:proton antiporter activity"")|go:""GO:0032991""(protein-containing complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0042995""(cell projection)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051015""(actin filament binding)|go:""GO:0055001""(muscle cell development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|go:""GO:1900025""(negative regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|refseq:NP_004915.2|dip:DIP-33179N|panther:PTHR11915(orthology-group)"	-	-	-	figure legend:3a, ST-2.1, ST-2.2|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606	intact-crc:24B5AC87CE9EBB8F|rigid:XsPlBopoJUgTncRqSnjf8zQ6rf8	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
intact:EBI-59039400	uniprotkb:P17301	uniparc:UPI0002A1D4FE	intact:EBI-702960|uniprotkb:Q14595|ensembl:ENSP00000296585.5	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	psi-mi:ita2_human(display_long)|uniprotkb:Platelet membrane glycoprotein Ia(gene name synonym)|uniprotkb:Collagen receptor(gene name synonym)|uniprotkb:VLA-2 subunit alpha(gene name synonym)|uniprotkb:CD49 antigen-like family member B(gene name synonym)|uniprotkb:ITGA2(gene name)|psi-mi:ITGA2(display_short)|uniprotkb:CD49B(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039443	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	genbank identifier:EKX94456(see-also)	"efo:""Orphanet:853""|ensembl:ENSG00000164171.11(gene)|ensembl:ENST00000296585.10(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002687""(positive regulation of leukocyte migration)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006929""(substrate-dependent cell migration)|go:""GO:0006971""(hypotonic response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007565""(female pregnancy)|go:""GO:0007596""(blood coagulation)|go:""GO:0008305""(integrin complex)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0014075""(response to amine)|go:""GO:0014850""(response to muscle activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030879""(mammary gland development)|go:""GO:0031346""(positive regulation of cell projection organization)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0033591""(response to L-ascorbic acid)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0038064""(collagen receptor activity)|go:""GO:0038065""(collagen-activated signaling pathway)|go:""GO:0043236""(laminin binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0043679""(axon terminus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045178""(basal part of cell)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045987""(positive regulation of smooth muscle contraction)|go:""GO:0046872""(metal ion binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050927""(positive regulation of positive chemotaxis)|go:""GO:0050966""(detection of mechanical stimulus involved in sensory perception of pain)|go:""GO:0051971""(positive regulation of transmission of nerve impulse)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0070365""(hepatocyte differentiation)|go:""GO:0071107""(response to parathyroid hormone)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|interpro:IPR048285|interpro:IPR048286|mint:P17301|rcsb pdb:1AOX|rcsb pdb:1DZI|rcsb pdb:1V7P|rcsb pdb:4BJ3|rcsb pdb:5HJ2|rcsb pdb:5THP|rcsb pdb:6ND8|rcsb pdb:6ND9|rcsb pdb:6NDA|rcsb pdb:6NDB|rcsb pdb:6NDC|rcsb pdb:6NDD|rcsb pdb:6NDE|rcsb pdb:6NDF|rcsb pdb:6NDG|rcsb pdb:6NDH|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-447041|reactome:R-HSA-75892|reactome:R-HSA-8874081|refseq:NP_002194.2|dip:DIP-67N|panther:PTHR23220(orthology-group)"	-	-	-	figure legend:3a, ST-2.1, ST-2.2|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	rogid:eT9f2vINJKqOgbGP+0BiXcVxiEs9606	intact-crc:24B5AC87CE9EBB8F|rigid:XsPlBopoJUgTncRqSnjf8zQ6rf8	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
intact:EBI-59039400	uniprotkb:P11216	uniparc:UPI0002A1D4FE	intact:EBI-1047231|uniprotkb:Q96AK1|uniprotkb:Q9NPX8|ensembl:ENSP00000216962.3	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	psi-mi:pygb_human(display_long)|uniprotkb:PYGB(gene name)|psi-mi:PYGB(display_short)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039443	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	genbank identifier:EKX94456(see-also)	"refseq:NP_002853.2|ensembl:ENSG00000100994.12(gene)|ensembl:ENST00000216962.9(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0008184""(glycogen phosphorylase activity)|go:""GO:0016020""(membrane)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0031220""(maltodextrin phosphorylase activity)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:P11216|rcsb pdb:5IKO|rcsb pdb:5IKP|reactome:R-HSA-6798695|reactome:R-HSA-70221|panther:PTHR11468(orthology-group)"	-	-	-	figure legend:3a, ST-2.1, ST-2.2|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	rogid:nJiqOiqRr155pMoMKe4PuD1DpLc9606	intact-crc:24B5AC87CE9EBB8F|rigid:XsPlBopoJUgTncRqSnjf8zQ6rf8	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
intact:EBI-59039400	uniprotkb:P13645	uniparc:UPI0002A1D4FE	intact:EBI-465144|uniprotkb:Q14664|uniprotkb:Q8N175|ensembl:ENSP00000269576.5	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	psi-mi:k1c10_human(display_long)|uniprotkb:KRT10(gene name)|psi-mi:KRT10(display_short)|uniprotkb:Cytokeratin-10(gene name synonym)|uniprotkb:KPP(gene name synonym)|uniprotkb:Keratin-10(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039443	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	genbank identifier:EKX94456(see-also)	"efo:""Orphanet:281139""|efo:""Orphanet:281190""|efo:""Orphanet:312""|efo:""Orphanet:512103""|panther:PTHR23239(orthology-group)|ensembl:ENSG00000186395.9(gene)|ensembl:ENST00000269576.6(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0008544""(epidermis development)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030280""(structural constituent of skin epidermis)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0045095""(keratin filament)|go:""GO:0045109""(intermediate filament organization)|go:""GO:0045684""(positive regulation of epidermis development)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051290""(protein heterotetramerization)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P13645|rcsb pdb:3ASW|rcsb pdb:4F1Z|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6EC0|rcsb pdb:6UUI|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9725554|refseq:NP_000412.3"	-	-	-	figure legend:3a, ST-2.1, ST-2.2|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	rogid:z100yyq3b63P0ARy2lE2ELyJeik9606	intact-crc:24B5AC87CE9EBB8F|rigid:XsPlBopoJUgTncRqSnjf8zQ6rf8	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
intact:EBI-59039400	uniprotkb:Q6PK50	uniparc:UPI0002A1D4FE	intact:EBI-9356629	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	psi-mi:q6pk50_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039443	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	genbank identifier:EKX94456(see-also)	"interpro:IPR036890|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|refseq:NP_001258901.1|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0120293""(dynein axonemal particle)|go:""GO:0140662""(ATP-dependent protein folding chaperone)"	-	-	-	figure legend:3a, ST-2.1, ST-2.2|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	rogid:vfuyuFWmhK9DZefAlEp5RFkxPhw9606	intact-crc:24B5AC87CE9EBB8F|rigid:XsPlBopoJUgTncRqSnjf8zQ6rf8	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
intact:EBI-59039400	uniprotkb:Q96BG6	uniparc:UPI0002A1D4FE	intact:EBI-59039564	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	psi-mi:q96bg6_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039443	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	genbank identifier:EKX94456(see-also)	"go:""GO:0003779""(actin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0015629""(actin cytoskeleton)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)"	-	-	-	figure legend:3a, ST-2.1, ST-2.2|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	rogid:PSrNGDPicz/l8qTQgX7I1tyjk5I9606	intact-crc:24B5AC87CE9EBB8F|rigid:XsPlBopoJUgTncRqSnjf8zQ6rf8	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
intact:EBI-59039400	uniprotkb:Q5XXA6	uniparc:UPI0002A1D4FE	intact:EBI-9031142|ensembl:ENSP00000347454.5|uniprotkb:A8KAM3|uniprotkb:Q8IYY8|uniprotkb:Q8N7V3|uniprotkb:A0A2H4Y9B2|uniprotkb:E9PNA7	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	psi-mi:ano1_human(display_long)|uniprotkb:ANO1(gene name)|psi-mi:ANO1(display_short)|uniprotkb:DOG1(gene name synonym)|uniprotkb:ORAOV2(gene name synonym)|uniprotkb:TAOS2(gene name synonym)|uniprotkb:TMEM16A(gene name synonym)|uniprotkb:Discovered on gastrointestinal stromal tumors protein 1(gene name synonym)|uniprotkb:Oral cancer overexpressed protein 2(gene name synonym)|uniprotkb:Transmembrane protein 16A(gene name synonym)|uniprotkb:Tumor-amplified and overexpressed sequence 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039443	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	genbank identifier:EKX94456(see-also)	"ensembl:ENSG00000131620.18(gene)|ensembl:ENST00000355303.10(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005227""(calcium-activated cation channel activity)|go:""GO:0005229""(intracellularly calcium-gated chloride channel activity)|go:""GO:0005247""(voltage-gated chloride channel activity)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006821""(chloride transport)|go:""GO:0007200""(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:0015111""(iodide transmembrane transporter activity)|go:""GO:0015705""(iodide transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034707""(chloride channel complex)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042995""(cell projection)|go:""GO:0046872""(metal ion binding)|go:""GO:0050965""(detection of temperature stimulus involved in sensory perception of pain)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070254""(mucus secretion)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0098793""(presynapse)|go:""GO:0106091""(glial cell projection elongation)|go:""GO:1901653""(cellular response to peptide)|go:""GO:1902476""(chloride transmembrane transport)|interpro:IPR007632(Protein of unknown function DUF590)|interpro:IPR032394|interpro:IPR049452|reactome:R-HSA-2672351|reactome:R-HSA-9733458|refseq:XP_011543433.1|refseq:NP_060513.5|refseq:XP_006718668.1|panther:PTHR12308(orthology-group)"	-	-	-	figure legend:3a, ST-2.1, ST-2.2|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	rogid:2F5w6esxRv6aNxz+1JI19+2873Y9606	intact-crc:24B5AC87CE9EBB8F|rigid:XsPlBopoJUgTncRqSnjf8zQ6rf8	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
intact:EBI-59039400	uniprotkb:P26641	uniparc:UPI0002A1D4FE	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901.4	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039443	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	genbank identifier:EKX94456(see-also)	"refseq:NP_001395.1|ensembl:ENSG00000254772.10(gene)|ensembl:ENST00000329251.5(transcript)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006414""(translational elongation)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|interpro:IPR050802|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|reactome:R-HSA-9725370|dip:DIP-32516N|panther:PTHR43986(orthology-group)"	-	-	-	figure legend:3a, ST-2.1, ST-2.2|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:24B5AC87CE9EBB8F|rigid:XsPlBopoJUgTncRqSnjf8zQ6rf8	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
intact:EBI-59039400	uniprotkb:Q96FA6	uniparc:UPI0002A1D4FE	intact:EBI-10285636	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	psi-mi:q96fa6_human(display_long)|uniprotkb:NCAPD3(gene name)|psi-mi:NCAPD3(display_short)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039443	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	genbank identifier:EKX94456(see-also)	"interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|interpro:IPR032682|go:""GO:0005634""(nucleus)|go:""GO:0007076""(mitotic chromosome condensation)|go:""GO:0051301""(cell division)"	-	-	-	figure legend:3a, ST-2.1, ST-2.2|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	rogid:ta7kkQzUhX1D0o0v5Y9o8yKHEoM9606	intact-crc:24B5AC87CE9EBB8F|rigid:XsPlBopoJUgTncRqSnjf8zQ6rf8	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
intact:EBI-59039400	uniprotkb:P05556	uniparc:UPI0002A1D4FE	intact:EBI-703066|intact:EBI-4289597|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5|ensembl:ENSP00000303351.3|ensembl:ENSP00000379350.2|ensembl:ENSP00000398029.2|ensembl:ENSP00000404546.3|ensembl:ENSP00000502882.1|ensembl:ENSP00000503546.1|ensembl:ENSP00000503916.1|ensembl:ENSP00000504205.1|ensembl:ENSP00000504444.1	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039443	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	genbank identifier:EKX94456(see-also)	"refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|ensembl:ENSG00000150093.20(gene)|ensembl:ENST00000302278.8(transcript)|ensembl:ENST00000396033.6(transcript)|ensembl:ENST00000417122.7(transcript)|ensembl:ENST00000437302.6(transcript)|ensembl:ENST00000677999.1(transcript)|ensembl:ENST00000678701.1(transcript)|ensembl:ENST00000678943.1(transcript)|ensembl:ENST00000678952.1(transcript)|dip:DIP-312N|ensembl:ENST00000678989.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001726""(ruffle)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002020""(protease binding)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006968""(cellular defense response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007517""(muscle organ development)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008305""(integrin complex)|go:""GO:0008354""(germ cell migration)|go:""GO:0008542""(visual learning)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010710""(regulation of collagen catabolic process)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0014704""(intercalated disc)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030175""(filopodium)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031623""(receptor internalization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0033631""(cell-cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034665""(integrin alpha1-beta1 complex)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0034667""(integrin alpha3-beta1 complex)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0034674""(integrin alpha5-beta1 complex)|go:""GO:0034675""(integrin alpha6-beta1 complex)|go:""GO:0034677""(integrin alpha7-beta1 complex)|go:""GO:0034678""(integrin alpha8-beta1 complex)|go:""GO:0034679""(integrin alpha9-beta1 complex)|go:""GO:0034680""(integrin alpha10-beta1 complex)|go:""GO:0034681""(integrin alpha11-beta1 complex)|go:""GO:0034682""(integrin alphav-beta1 complex)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043197""(dendritic spine)|go:""GO:0043235""(receptor complex)|go:""GO:0043236""(laminin binding)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045743""(positive regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048626""(myoblast fate specification)|go:""GO:0048675""(axon extension)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051951""(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0055037""(recycling endosome)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060912""(cardiac cell fate specification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097386""(glial cell projection)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150053""(cerebellar climbing fiber to Purkinje cell synapse)|go:""GO:0150103""(reactive gliosis)|go:""GO:1900748""(positive regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901979""(regulation of inward rectifier potassium channel activity)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905806""(regulation of synapse pruning)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|rcsb pdb:7CEB|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEC|rcsb pdb:7NWL|rcsb pdb:7NXD|rcsb pdb:8RPQ|rcsb pdb:9CKV|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9634597|reactome:R-HSA-9679191|reactome:R-HSA-9725554|reactome:R-HSA-9830674|reactome:R-HSA-9860927|panther:PTHR10082(orthology-group)"	-	-	-	figure legend:3a, ST-2.1, ST-2.2|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	intact-crc:24B5AC87CE9EBB8F|rigid:XsPlBopoJUgTncRqSnjf8zQ6rf8	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
matrixdb:MULT_25_human	intact:EBI-59039400	intact:EBI-2565102|reactome:R-HSA-114561|chembl target:CHEMBL3137268|signor:SIGNOR-C160	uniparc:UPI0002A1D4FE	"psi-mi:intg_a2_b1_human(display_short)|psi-mi:MULT_25_human(display_long)|intact:alpha-2/beta-1 integrin complex(complex synonym)|intact:""ITGA2:ITGB1""(complex systematic name)|intact:Integrin alpha2-beta1 complex(complex recommended name)|intact:alpha2-beta1 integrin complex(complex synonym)"	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039622	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:1302""(stable complex)"	"psi-mi:""MI:0326""(protein)"	"intact:EBI-703266(exp-evidence)|pubmed:19693543(see-also)|pubmed:12297042(see-also)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0030198""(extracellular matrix organization)|humap:huMAP3_06815.1(superset)|complex portal:CPX-1801(complex-primary)|evidence ontology:""ECO:0000353"""	genbank identifier:EKX94456(see-also)	-	curated-complex:Cell adhesion, bi-directional signaling receptor which functions as a link between the extra-cellular matrix and the cytoskeleton. Receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the sequence G-F-P-G-E-R in a wide array of ligands. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.|complex-properties:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. The ligand-binding site forms in a region at the intersection of the integrin alpha-chain beta-propeller and the betaI domain, with the alpha chain being central in determining ligand specificity.|complex-assembly:Heterodimer	-	figure legend:3b|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2024/11/15	-	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	intact-crc:0507EBE942661E71	false	-	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
matrixdb:MULT_25_human	intact:EBI-59039400	intact:EBI-2565102|reactome:R-HSA-114561|chembl target:CHEMBL3137268|signor:SIGNOR-C160	uniparc:UPI0002A1D4FE	"psi-mi:intg_a2_b1_human(display_short)|psi-mi:MULT_25_human(display_long)|intact:alpha-2/beta-1 integrin complex(complex synonym)|intact:""ITGA2:ITGB1""(complex systematic name)|intact:Integrin alpha2-beta1 complex(complex recommended name)|intact:alpha2-beta1 integrin complex(complex synonym)"	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039629	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:1302""(stable complex)"	"psi-mi:""MI:0326""(protein)"	"intact:EBI-703266(exp-evidence)|pubmed:19693543(see-also)|pubmed:12297042(see-also)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0030198""(extracellular matrix organization)|humap:huMAP3_06815.1(superset)|complex portal:CPX-1801(complex-primary)|evidence ontology:""ECO:0000353"""	genbank identifier:EKX94456(see-also)	-	curated-complex:Cell adhesion, bi-directional signaling receptor which functions as a link between the extra-cellular matrix and the cytoskeleton. Receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the sequence G-F-P-G-E-R in a wide array of ligands. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.|complex-properties:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. The ligand-binding site forms in a region at the intersection of the integrin alpha-chain beta-propeller and the betaI domain, with the alpha chain being central in determining ligand specificity.|complex-assembly:Heterodimer	-	figure legend:3b|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2024/11/15	-	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	intact-crc:CC7A007A92A86E79	false	-	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
matrixdb:MULT_25_human	intact:EBI-59039400	intact:EBI-2565102|reactome:R-HSA-114561|chembl target:CHEMBL3137268|signor:SIGNOR-C160	uniparc:UPI0002A1D4FE	"psi-mi:intg_a2_b1_human(display_short)|psi-mi:MULT_25_human(display_long)|intact:alpha-2/beta-1 integrin complex(complex synonym)|intact:""ITGA2:ITGB1""(complex systematic name)|intact:Integrin alpha2-beta1 complex(complex recommended name)|intact:alpha2-beta1 integrin complex(complex synonym)"	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039636	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:1302""(stable complex)"	"psi-mi:""MI:0326""(protein)"	"intact:EBI-703266(exp-evidence)|pubmed:19693543(see-also)|pubmed:12297042(see-also)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0030198""(extracellular matrix organization)|humap:huMAP3_06815.1(superset)|complex portal:CPX-1801(complex-primary)|evidence ontology:""ECO:0000353"""	genbank identifier:EKX94456(see-also)	-	curated-complex:Cell adhesion, bi-directional signaling receptor which functions as a link between the extra-cellular matrix and the cytoskeleton. Receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the sequence G-F-P-G-E-R in a wide array of ligands. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.|complex-properties:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. The ligand-binding site forms in a region at the intersection of the integrin alpha-chain beta-propeller and the betaI domain, with the alpha chain being central in determining ligand specificity.|complex-assembly:Heterodimer	-	figure legend:3b|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2024/11/15	-	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	intact-crc:20BDD2B74B55236A	false	-	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
matrixdb:MULT_25_human	intact:EBI-59039400	intact:EBI-2565102|reactome:R-HSA-114561|chembl target:CHEMBL3137268|signor:SIGNOR-C160	uniparc:UPI0002A1D4FE	"psi-mi:intg_a2_b1_human(display_short)|psi-mi:MULT_25_human(display_long)|intact:alpha-2/beta-1 integrin complex(complex synonym)|intact:""ITGA2:ITGB1""(complex systematic name)|intact:Integrin alpha2-beta1 complex(complex recommended name)|intact:alpha2-beta1 integrin complex(complex synonym)"	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039643	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:1302""(stable complex)"	"psi-mi:""MI:0326""(protein)"	"intact:EBI-703266(exp-evidence)|pubmed:19693543(see-also)|pubmed:12297042(see-also)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0030198""(extracellular matrix organization)|humap:huMAP3_06815.1(superset)|complex portal:CPX-1801(complex-primary)|evidence ontology:""ECO:0000353"""	genbank identifier:EKX94456(see-also)	-	curated-complex:Cell adhesion, bi-directional signaling receptor which functions as a link between the extra-cellular matrix and the cytoskeleton. Receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the sequence G-F-P-G-E-R in a wide array of ligands. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.|complex-properties:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. The ligand-binding site forms in a region at the intersection of the integrin alpha-chain beta-propeller and the betaI domain, with the alpha chain being central in determining ligand specificity.|complex-assembly:Heterodimer	-	figure legend:3b|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2024/11/15	-	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	intact-crc:03912D14D0C8AB2B	false	-	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P17301	intact:EBI-59039400	intact:EBI-702960|uniprotkb:Q14595|ensembl:ENSP00000296585.5	uniparc:UPI0002A1D4FE	psi-mi:ita2_human(display_long)|uniprotkb:Platelet membrane glycoprotein Ia(gene name synonym)|uniprotkb:Collagen receptor(gene name synonym)|uniprotkb:VLA-2 subunit alpha(gene name synonym)|uniprotkb:CD49 antigen-like family member B(gene name synonym)|uniprotkb:ITGA2(gene name)|psi-mi:ITGA2(display_short)|uniprotkb:CD49B(gene name synonym)	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039784	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:853""|ensembl:ENSG00000164171.11(gene)|ensembl:ENST00000296585.10(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002687""(positive regulation of leukocyte migration)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006929""(substrate-dependent cell migration)|go:""GO:0006971""(hypotonic response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007565""(female pregnancy)|go:""GO:0007596""(blood coagulation)|go:""GO:0008305""(integrin complex)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0014075""(response to amine)|go:""GO:0014850""(response to muscle activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030879""(mammary gland development)|go:""GO:0031346""(positive regulation of cell projection organization)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0033591""(response to L-ascorbic acid)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0038064""(collagen receptor activity)|go:""GO:0038065""(collagen-activated signaling pathway)|go:""GO:0043236""(laminin binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0043679""(axon terminus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045178""(basal part of cell)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045987""(positive regulation of smooth muscle contraction)|go:""GO:0046872""(metal ion binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050927""(positive regulation of positive chemotaxis)|go:""GO:0050966""(detection of mechanical stimulus involved in sensory perception of pain)|go:""GO:0051971""(positive regulation of transmission of nerve impulse)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0070365""(hepatocyte differentiation)|go:""GO:0071107""(response to parathyroid hormone)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|interpro:IPR048285|interpro:IPR048286|mint:P17301|rcsb pdb:1AOX|rcsb pdb:1DZI|rcsb pdb:1V7P|rcsb pdb:4BJ3|rcsb pdb:5HJ2|rcsb pdb:5THP|rcsb pdb:6ND8|rcsb pdb:6ND9|rcsb pdb:6NDA|rcsb pdb:6NDB|rcsb pdb:6NDC|rcsb pdb:6NDD|rcsb pdb:6NDE|rcsb pdb:6NDF|rcsb pdb:6NDG|rcsb pdb:6NDH|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-447041|reactome:R-HSA-75892|reactome:R-HSA-8874081|refseq:NP_002194.2|dip:DIP-67N|panther:PTHR23220(orthology-group)"	genbank identifier:EKX94456(see-also)	-	-	-	figure legend:3c|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/01/27	rogid:eT9f2vINJKqOgbGP+0BiXcVxiEs9606	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	intact-crc:012B141435364DA3|rigid:y/G6vW2CjXUfW95i1SOb5MHKEvE	false	-	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P05556	intact:EBI-59039400	intact:EBI-703066|intact:EBI-4289597|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5|ensembl:ENSP00000303351.3|ensembl:ENSP00000379350.2|ensembl:ENSP00000398029.2|ensembl:ENSP00000404546.3|ensembl:ENSP00000502882.1|ensembl:ENSP00000503546.1|ensembl:ENSP00000503916.1|ensembl:ENSP00000504205.1|ensembl:ENSP00000504444.1	uniparc:UPI0002A1D4FE	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:pcwbr2_9firm(display_short)|psi-mi:EBI-59039400(display_long)	"psi-mi:""MI:0096""(pull down)"	Long et al. (2019)	pubmed:31501538|imex:IM-30136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:596329(9firm)|taxid:596329(Peptostreptococcus anaerobius 653-L)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-59039790	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|ensembl:ENSG00000150093.20(gene)|ensembl:ENST00000302278.8(transcript)|ensembl:ENST00000396033.6(transcript)|ensembl:ENST00000417122.7(transcript)|ensembl:ENST00000437302.6(transcript)|ensembl:ENST00000677999.1(transcript)|ensembl:ENST00000678701.1(transcript)|ensembl:ENST00000678943.1(transcript)|ensembl:ENST00000678952.1(transcript)|dip:DIP-312N|ensembl:ENST00000678989.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001726""(ruffle)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002020""(protease binding)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006968""(cellular defense response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007517""(muscle organ development)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008305""(integrin complex)|go:""GO:0008354""(germ cell migration)|go:""GO:0008542""(visual learning)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010710""(regulation of collagen catabolic process)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0014704""(intercalated disc)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030175""(filopodium)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031623""(receptor internalization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0033631""(cell-cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034665""(integrin alpha1-beta1 complex)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0034667""(integrin alpha3-beta1 complex)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0034674""(integrin alpha5-beta1 complex)|go:""GO:0034675""(integrin alpha6-beta1 complex)|go:""GO:0034677""(integrin alpha7-beta1 complex)|go:""GO:0034678""(integrin alpha8-beta1 complex)|go:""GO:0034679""(integrin alpha9-beta1 complex)|go:""GO:0034680""(integrin alpha10-beta1 complex)|go:""GO:0034681""(integrin alpha11-beta1 complex)|go:""GO:0034682""(integrin alphav-beta1 complex)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043197""(dendritic spine)|go:""GO:0043235""(receptor complex)|go:""GO:0043236""(laminin binding)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045743""(positive regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048626""(myoblast fate specification)|go:""GO:0048675""(axon extension)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051951""(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0055037""(recycling endosome)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060912""(cardiac cell fate specification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097386""(glial cell projection)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150053""(cerebellar climbing fiber to Purkinje cell synapse)|go:""GO:0150103""(reactive gliosis)|go:""GO:1900748""(positive regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901979""(regulation of inward rectifier potassium channel activity)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905806""(regulation of synapse pruning)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|rcsb pdb:7CEB|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEC|rcsb pdb:7NWL|rcsb pdb:7NXD|rcsb pdb:8RPQ|rcsb pdb:9CKV|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9634597|reactome:R-HSA-9679191|reactome:R-HSA-9725554|reactome:R-HSA-9830674|reactome:R-HSA-9860927|panther:PTHR10082(orthology-group)"	genbank identifier:EKX94456(see-also)	-	-	-	figure legend:3c|curation depth:imex curation|dataset:IBD - Inflammatory bowel disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/10/15	2025/03/25	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rogid:HtuBTn7rj9bbGppN7eHTDqPYjVc596329	intact-crc:CB5274E7FAC850F0|rigid:Kdm1knNe6d4eHBttUhOwbo8tLAI	false	-	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q7Z7E8	uniprotkb:Q5ZSJ1	intact:EBI-1783287|ensembl:ENSP00000292211.4|uniprotkb:Q3B841|uniprotkb:Q5I0X2|uniprotkb:Q6IS04|uniprotkb:Q6P7P2|uniprotkb:Q96MV4|uniprotkb:Q9BVX5|uniprotkb:Q9UGL6|uniprotkb:B4DF92|uniprotkb:Q29SN7	intact:EBI-59042461	psi-mi:ub2q1_human(display_long)|uniprotkb:UBE2Q1(gene name)|psi-mi:UBE2Q1(display_short)|uniprotkb:NICE5(gene name synonym)|uniprotkb:UBE2Q(gene name synonym)|uniprotkb:PRO3094(orf name)|uniprotkb:Ubiquitin-protein ligase Q1(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q1(gene name synonym)|uniprotkb:Protein NICE-5(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q1(gene name synonym)	psi-mi:q5zsj1_legph(display_long)|uniprotkb:lpg2526(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Voth et al. (2021)	pubmed:34944446|imex:IM-30138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-59042473	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000160714.11(gene)|ensembl:ENST00000292211.5(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001967""(suckling behavior)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007566""(embryo implantation)|go:""GO:0007617""(mating behavior)|go:""GO:0009566""(fertilization)|go:""GO:0030175""(filopodium)|go:""GO:0061458""(reproductive system development)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070459""(prolactin secretion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q7Z7E8|rcsb pdb:2QGX|reactome:R-HSA-983168|refseq:NP_060052.3|panther:PTHR24068(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0072570""(ADP-D-ribose binding)|rcsb pdb:8IPJ|rcsb pdb:8IPW|refseq:WP_010948228.1|refseq:YP_096533.1|rcsb pdb:6OMI|rcsb pdb:8DMP|rcsb pdb:8DMQ|rcsb pdb:8DMR|rcsb pdb:8DMS|rcsb pdb:8XEP"	-	-	-	figure legend:2A|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2024/10/17	2024/11/14	rogid:Jxlo/WdqxS0sfr76bmPqj9AnYE09606	rogid:tUpZXiBmg4FPb8urPJzuxoTh6Vo272624	intact-crc:075DAF161C2D72FD|rigid:i0c0Vrd2v5vJfjSW9rXQZajtDTM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5ZSJ1	uniprotkb:Q7Z7E8	intact:EBI-59042461	intact:EBI-1783287|ensembl:ENSP00000292211.4|uniprotkb:Q3B841|uniprotkb:Q5I0X2|uniprotkb:Q6IS04|uniprotkb:Q6P7P2|uniprotkb:Q96MV4|uniprotkb:Q9BVX5|uniprotkb:Q9UGL6|uniprotkb:B4DF92|uniprotkb:Q29SN7	psi-mi:q5zsj1_legph(display_long)|uniprotkb:lpg2526(locus name)	psi-mi:ub2q1_human(display_long)|uniprotkb:UBE2Q1(gene name)|psi-mi:UBE2Q1(display_short)|uniprotkb:NICE5(gene name synonym)|uniprotkb:UBE2Q(gene name synonym)|uniprotkb:PRO3094(orf name)|uniprotkb:Ubiquitin-protein ligase Q1(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q1(gene name synonym)|uniprotkb:Protein NICE-5(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Voth et al. (2021)	pubmed:34944446|imex:IM-30138	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-59042485	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0072570""(ADP-D-ribose binding)|rcsb pdb:8IPJ|rcsb pdb:8IPW|refseq:WP_010948228.1|refseq:YP_096533.1|rcsb pdb:6OMI|rcsb pdb:8DMP|rcsb pdb:8DMQ|rcsb pdb:8DMR|rcsb pdb:8DMS|rcsb pdb:8XEP"	"ensembl:ENSG00000160714.11(gene)|ensembl:ENST00000292211.5(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001967""(suckling behavior)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007566""(embryo implantation)|go:""GO:0007617""(mating behavior)|go:""GO:0009566""(fertilization)|go:""GO:0030175""(filopodium)|go:""GO:0061458""(reproductive system development)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070459""(prolactin secretion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q7Z7E8|rcsb pdb:2QGX|reactome:R-HSA-983168|refseq:NP_060052.3|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:2B|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2024/10/17	2024/11/14	rogid:tUpZXiBmg4FPb8urPJzuxoTh6Vo272624	rogid:Jxlo/WdqxS0sfr76bmPqj9AnYE09606	intact-crc:EDEA4CC4948A7B3A|rigid:i0c0Vrd2v5vJfjSW9rXQZajtDTM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5ZSJ1	uniprotkb:Q7Z7E8	intact:EBI-59042461	intact:EBI-1783287|ensembl:ENSP00000292211.4|uniprotkb:Q3B841|uniprotkb:Q5I0X2|uniprotkb:Q6IS04|uniprotkb:Q6P7P2|uniprotkb:Q96MV4|uniprotkb:Q9BVX5|uniprotkb:Q9UGL6|uniprotkb:B4DF92|uniprotkb:Q29SN7	psi-mi:q5zsj1_legph(display_long)|uniprotkb:lpg2526(locus name)	psi-mi:ub2q1_human(display_long)|uniprotkb:UBE2Q1(gene name)|psi-mi:UBE2Q1(display_short)|uniprotkb:NICE5(gene name synonym)|uniprotkb:UBE2Q(gene name synonym)|uniprotkb:PRO3094(orf name)|uniprotkb:Ubiquitin-protein ligase Q1(gene name synonym)|uniprotkb:Ubiquitin carrier protein Q1(gene name synonym)|uniprotkb:Protein NICE-5(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme Q1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Voth et al. (2021)	pubmed:34944446|imex:IM-30138	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-59042513	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0072570""(ADP-D-ribose binding)|rcsb pdb:8IPJ|rcsb pdb:8IPW|refseq:WP_010948228.1|refseq:YP_096533.1|rcsb pdb:6OMI|rcsb pdb:8DMP|rcsb pdb:8DMQ|rcsb pdb:8DMR|rcsb pdb:8DMS|rcsb pdb:8XEP"	"ensembl:ENSG00000160714.11(gene)|ensembl:ENST00000292211.5(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001967""(suckling behavior)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007566""(embryo implantation)|go:""GO:0007617""(mating behavior)|go:""GO:0009566""(fertilization)|go:""GO:0030175""(filopodium)|go:""GO:0061458""(reproductive system development)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070459""(prolactin secretion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q7Z7E8|rcsb pdb:2QGX|reactome:R-HSA-983168|refseq:NP_060052.3|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:2C|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2024/10/17	2024/11/14	rogid:tUpZXiBmg4FPb8urPJzuxoTh6Vo272624	rogid:Jxlo/WdqxS0sfr76bmPqj9AnYE09606	intact-crc:2DCFB8C5B8F9F126|rigid:i0c0Vrd2v5vJfjSW9rXQZajtDTM	false	enhanced green fluorescent protein tag:c-c	flag tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
intact:EBI-55021380	uniprotkb:Q15052	-	intact:EBI-1642523|uniprotkb:A6NMW9|uniprotkb:A8K6S7|uniprotkb:Q15396|uniprotkb:Q5JQ66|uniprotkb:Q7Z3W1|uniprotkb:Q86XH0|uniprotkb:B1AL37|ensembl:ENSP00000250617.6	psi-mi:a0a2x5aby1_helpx(display_short)|psi-mi:EBI-55021380(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:NCTC11637_00769(orf name)	psi-mi:arhg6_human(display_long)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Baek et al. (2007)	pubmed:17405911|imex:IM-30077	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55021401	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A2X5ABY1(uniprot-removed-ac)	"ensembl:ENST00000250617.7(transcript)|dip:DIP-42694N|ensembl:ENSG00000129675.16(gene)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006915""(apoptotic process)|go:""GO:0007254""(JNK cascade)|go:""GO:0030027""(lamellipodium)|go:""GO:0030032""(lamellipodium assembly)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|interpro:IPR046376|mint:Q15052|rcsb pdb:1UJY|rcsb pdb:1WYR|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-446388|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420|refseq:NP_001293106.1|refseq:NP_004831.1|efo:""Orphanet:777""|panther:PTHR46026(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:fig. 1|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/05/16	2025/01/25	rogid:+l6fLadQBOYB2TQZua2T73ADnKw102618	rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606	intact-crc:B01EF4AF70CE831D|rigid:OmyXRJrw4WewcYc+7UAi2Sw+lQU	false	-	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
intact:EBI-55021380	uniprotkb:Q15052	-	intact:EBI-1642523|uniprotkb:A6NMW9|uniprotkb:A8K6S7|uniprotkb:Q15396|uniprotkb:Q5JQ66|uniprotkb:Q7Z3W1|uniprotkb:Q86XH0|uniprotkb:B1AL37|ensembl:ENSP00000250617.6	psi-mi:a0a2x5aby1_helpx(display_short)|psi-mi:EBI-55021380(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:NCTC11637_00769(orf name)	psi-mi:arhg6_human(display_long)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Baek et al. (2007)	pubmed:17405911|imex:IM-30077	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55021377	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A2X5ABY1(uniprot-removed-ac)	"ensembl:ENST00000250617.7(transcript)|dip:DIP-42694N|ensembl:ENSG00000129675.16(gene)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006915""(apoptotic process)|go:""GO:0007254""(JNK cascade)|go:""GO:0030027""(lamellipodium)|go:""GO:0030032""(lamellipodium assembly)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|interpro:IPR046376|mint:Q15052|rcsb pdb:1UJY|rcsb pdb:1WYR|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-446388|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420|refseq:NP_001293106.1|refseq:NP_004831.1|efo:""Orphanet:777""|panther:PTHR46026(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:fig. 2|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/05/16	2025/01/25	rogid:+l6fLadQBOYB2TQZua2T73ADnKw102618	rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606	intact-crc:F11DE7E200CE1735|rigid:OmyXRJrw4WewcYc+7UAi2Sw+lQU	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q15052	intact:EBI-55021380	intact:EBI-1642523|uniprotkb:A6NMW9|uniprotkb:A8K6S7|uniprotkb:Q15396|uniprotkb:Q5JQ66|uniprotkb:Q7Z3W1|uniprotkb:Q86XH0|uniprotkb:B1AL37|ensembl:ENSP00000250617.6	-	psi-mi:arhg6_human(display_long)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)	psi-mi:a0a2x5aby1_helpx(display_short)|psi-mi:EBI-55021380(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:NCTC11637_00769(orf name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Baek et al. (2007)	pubmed:17405911|imex:IM-30077	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55021397	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENST00000250617.7(transcript)|dip:DIP-42694N|ensembl:ENSG00000129675.16(gene)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006915""(apoptotic process)|go:""GO:0007254""(JNK cascade)|go:""GO:0030027""(lamellipodium)|go:""GO:0030032""(lamellipodium assembly)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|interpro:IPR046376|mint:Q15052|rcsb pdb:1UJY|rcsb pdb:1WYR|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-446388|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420|refseq:NP_001293106.1|refseq:NP_004831.1|efo:""Orphanet:777""|panther:PTHR46026(orthology-group)"	uniprotkb:A0A2X5ABY1(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:fig. 2|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/05/16	2025/01/25	rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606	rogid:+l6fLadQBOYB2TQZua2T73ADnKw102618	intact-crc:56E174C0BE0D5EC5|rigid:OmyXRJrw4WewcYc+7UAi2Sw+lQU	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
intact:EBI-55021380	uniprotkb:P12830	-	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|uniprotkb:Q9UII8|ensembl:ENSP00000261769.4	psi-mi:a0a2x5aby1_helpx(display_short)|psi-mi:EBI-55021380(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:NCTC11637_00769(orf name)	psi-mi:cadh1_human(display_long)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Murata-Kamiya et al. (2007)	pubmed:17237808|imex:IM-30078	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55022057	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A2X5ABY1(uniprot-removed-ac)	"efo:""Orphanet:1331""|efo:""Orphanet:199306""|efo:""Orphanet:1997""|efo:""Orphanet:227535""|efo:""Orphanet:26106""|ensembl:ENSG00000039068.20(gene)|ensembl:ENST00000261769.10(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007416""(synapse assembly)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016339""(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0016600""(flotillin complex)|go:""GO:0021983""(pituitary gland development)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030057""(desmosome)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030506""(ankyrin binding)|go:""GO:0030517""(negative regulation of axon extension)|go:""GO:0031175""(neuron projection development)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071285""(cellular response to lithium ion)|go:""GO:0071503""(response to heparin)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099576""(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:""GO:0140459""(response to Gram-positive bacterium)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6VEL|rcsb pdb:7STZ|rcsb pdb:8H62|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|reactome:R-HSA-9823730|reactome:R-HSA-9856649|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|refseq:NP_004351.1|dip:DIP-477N|panther:PTHR24027(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:fig. 2a-c, suppl. fig.1|curation depth:imex curation	taxid:9606(human-mkn28)|taxid:9606(Homo sapiens MKN28 gastric tubular adenocarcinoma cell)	-	2024/05/21	2025/03/18	rogid:+l6fLadQBOYB2TQZua2T73ADnKw102618	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	intact-crc:4B55312214CD1BDE|rigid:af+H2lMPtY2X6Q3w/6O14kTskIQ	false	ha tag:?-?|mutation with no effect:965-965,999-999,1033-1033,893-893,912-912	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P12830	intact:EBI-55021380	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|uniprotkb:Q9UII8|ensembl:ENSP00000261769.4	-	psi-mi:cadh1_human(display_long)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	psi-mi:a0a2x5aby1_helpx(display_short)|psi-mi:EBI-55021380(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:NCTC11637_00769(orf name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Murata-Kamiya et al. (2007)	pubmed:17237808|imex:IM-30078	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55022078	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1331""|efo:""Orphanet:199306""|efo:""Orphanet:1997""|efo:""Orphanet:227535""|efo:""Orphanet:26106""|ensembl:ENSG00000039068.20(gene)|ensembl:ENST00000261769.10(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007416""(synapse assembly)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016339""(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0016600""(flotillin complex)|go:""GO:0021983""(pituitary gland development)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030057""(desmosome)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030506""(ankyrin binding)|go:""GO:0030517""(negative regulation of axon extension)|go:""GO:0031175""(neuron projection development)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071285""(cellular response to lithium ion)|go:""GO:0071503""(response to heparin)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099576""(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:""GO:0140459""(response to Gram-positive bacterium)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6VEL|rcsb pdb:7STZ|rcsb pdb:8H62|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|reactome:R-HSA-9823730|reactome:R-HSA-9856649|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|refseq:NP_004351.1|dip:DIP-477N|panther:PTHR24027(orthology-group)"	uniprotkb:A0A2X5ABY1(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	"figure legend:fig. 2c|comment:""\""Thus, CagA interacts with E-cadherin in a tyrosine phosphorylation-independent manner. Importantly, the CagA/E-cadherin complex failed to pull down β-catenin (Figure 2b, lane 2), whereas direct immunoprecipitation of the comparable amount of E-cadherin co-precipitated β-catenin (Figure 2b, lanes 3–5). The results indicated that the CagA/E-cadherin complex does not contain β-catenin.\""""|curation depth:imex curation"	taxid:9606(human-mkn28)|taxid:9606(Homo sapiens MKN28 gastric tubular adenocarcinoma cell)	-	2024/05/21	2025/03/18	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	rogid:+l6fLadQBOYB2TQZua2T73ADnKw102618	intact-crc:ACEABA015CAE72D7|rigid:af+H2lMPtY2X6Q3w/6O14kTskIQ	false	-	ha tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P12830	uniprotkb:A0A0S2C3P2	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|uniprotkb:Q9UII8|ensembl:ENSP00000261769.4	intact:EBI-55025805	psi-mi:cadh1_human(display_long)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	psi-mi:a0a0s2c3p2_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Oliveira et al. (2009)	pubmed:19604117|imex:IM-30087	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:210(helpx)|taxid:210(Helicobacter pylori)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55025802	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1331""|efo:""Orphanet:199306""|efo:""Orphanet:1997""|efo:""Orphanet:227535""|efo:""Orphanet:26106""|ensembl:ENSG00000039068.20(gene)|ensembl:ENST00000261769.10(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007416""(synapse assembly)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016339""(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0016600""(flotillin complex)|go:""GO:0021983""(pituitary gland development)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030057""(desmosome)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030506""(ankyrin binding)|go:""GO:0030517""(negative regulation of axon extension)|go:""GO:0031175""(neuron projection development)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071285""(cellular response to lithium ion)|go:""GO:0071503""(response to heparin)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099576""(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:""GO:0140459""(response to Gram-positive bacterium)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6VEL|rcsb pdb:7STZ|rcsb pdb:8H62|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|reactome:R-HSA-9823730|reactome:R-HSA-9856649|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|refseq:NP_004351.1|dip:DIP-477N|panther:PTHR24027(orthology-group)"	mint:A0A0S2C3P2	-	-	-	"figure legend:FIG. 4B|comment:""\""Analysis of the xz and yz confocal sections suggest that, after 1 h of infection of AGSEcad cells, CagA partially colocalizes with E-cadherin and with p120-catenin. An immunofluorescent signal corresponding to CagA was also visualized in areas negative for p120-catenin and E-cadherin (figure 4B).\""""|curation depth:imex curation"	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/05/21	2025/03/18	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	rogid:9TCJUx+Z9xQ/WI3syaoLpp++iIg210	intact-crc:BEBDC17482019094|rigid:NFajG0/G+PcCqKx0l8IckzKNqS0	false	-	-	-	-	"psi-mi:""MI:1198""(immunohistochemistry)"	"psi-mi:""MI:1198""(immunohistochemistry)"
uniprotkb:O60716	uniprotkb:A0A0S2C3P2	intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004.5	intact:EBI-55025805	"psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:""p120(cas)""(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym)"	psi-mi:a0a0s2c3p2_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Oliveira et al. (2009)	pubmed:19604117|imex:IM-30087	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:210(helpx)|taxid:210(Helicobacter pylori)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55025811	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000198561.16(gene)|ensembl:ENST00000399050.10(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009986""(cell surface)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016342""(catenin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030426""(growth cone)|go:""GO:0030496""(midbody)|go:""GO:0043197""(dendritic spine)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045296""(cadherin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098831""(presynaptic active zone cytoplasmic component)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0150107""(positive regulation of protein localization to cell-cell junction)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9833576|refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|efo:""Orphanet:1997""|dip:DIP-33850N|panther:PTHR10372(orthology-group)"	mint:A0A0S2C3P2	-	-	-	"figure legend:FIG. 4B|comment:""\""Analysis of the xz and yz confocal sections suggest that, after 1 h of infection of AGSEcad cells, CagA partially colocalizes with E-cadherin and with p120-catenin. An immunofluorescent signal corresponding to CagA was also visualized in areas negative for p120-catenin and E-cadherin (figure 4B).\""""|curation depth:imex curation"	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/05/21	2025/02/28	rogid:HgMvbcDKedE291TIvIOqLFT3srw9606	rogid:9TCJUx+Z9xQ/WI3syaoLpp++iIg210	intact-crc:CCF75A233265A38D|rigid:UXNZoBDx1b/21Y+3iSlfaD4OF5g	false	-	-	-	-	"psi-mi:""MI:1198""(immunohistochemistry)"	"psi-mi:""MI:1198""(immunohistochemistry)"
uniprotkb:A0A0S2C3P2	uniprotkb:P12830	intact:EBI-55025805	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|uniprotkb:Q9UII8|ensembl:ENSP00000261769.4	psi-mi:a0a0s2c3p2_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	psi-mi:cadh1_human(display_long)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Oliveira et al. (2009)	pubmed:19604117|imex:IM-30087	taxid:210(helpx)|taxid:210(Helicobacter pylori)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55025821	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:A0A0S2C3P2	"efo:""Orphanet:1331""|efo:""Orphanet:199306""|efo:""Orphanet:1997""|efo:""Orphanet:227535""|efo:""Orphanet:26106""|ensembl:ENSG00000039068.20(gene)|ensembl:ENST00000261769.10(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007416""(synapse assembly)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016339""(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0016600""(flotillin complex)|go:""GO:0021983""(pituitary gland development)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030057""(desmosome)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030506""(ankyrin binding)|go:""GO:0030517""(negative regulation of axon extension)|go:""GO:0031175""(neuron projection development)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071285""(cellular response to lithium ion)|go:""GO:0071503""(response to heparin)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099576""(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:""GO:0140459""(response to Gram-positive bacterium)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6VEL|rcsb pdb:7STZ|rcsb pdb:8H62|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|reactome:R-HSA-9823730|reactome:R-HSA-9856649|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|refseq:NP_004351.1|dip:DIP-477N|panther:PTHR24027(orthology-group)"	-	-	-	figure legend:fig. 5a|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/05/21	2025/03/18	rogid:9TCJUx+Z9xQ/WI3syaoLpp++iIg210	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	intact-crc:DB0C010364E04A85|rigid:NFajG0/G+PcCqKx0l8IckzKNqS0	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:O60716	uniprotkb:A0A0S2C3P2	intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004.5	intact:EBI-55025805	"psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:""p120(cas)""(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym)"	psi-mi:a0a0s2c3p2_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Oliveira et al. (2009)	pubmed:19604117|imex:IM-30087	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:210(helpx)|taxid:210(Helicobacter pylori)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55025825	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000198561.16(gene)|ensembl:ENST00000399050.10(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009986""(cell surface)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016342""(catenin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030426""(growth cone)|go:""GO:0030496""(midbody)|go:""GO:0043197""(dendritic spine)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045296""(cadherin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098831""(presynaptic active zone cytoplasmic component)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0150107""(positive regulation of protein localization to cell-cell junction)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9833576|refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|efo:""Orphanet:1997""|dip:DIP-33850N|panther:PTHR10372(orthology-group)"	mint:A0A0S2C3P2	-	-	-	figure legend:fig. 5a|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/05/21	2025/02/28	rogid:HgMvbcDKedE291TIvIOqLFT3srw9606	rogid:9TCJUx+Z9xQ/WI3syaoLpp++iIg210	intact-crc:344C82F2C163C192|rigid:UXNZoBDx1b/21Y+3iSlfaD4OF5g	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P08581	uniprotkb:A0A0S2C3P2	intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860.3	intact:EBI-55025805	psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym)	psi-mi:a0a0s2c3p2_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Oliveira et al. (2009)	pubmed:19604117|imex:IM-30087	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:210(helpx)|taxid:210(Helicobacter pylori)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55025829	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105976.16(gene)|ensembl:ENST00000397752.8(transcript)|go:""GO:0001886""(endothelial cell morphogenesis)|go:""GO:0001889""(liver development)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006909""(phagocytosis)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0031016""(pancreas development)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0061436""(establishment of skin barrier)|go:""GO:0070495""(negative regulation of thrombin-activated receptor signaling pathway)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0098794""(postsynapse)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1901299""(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:""GO:1905098""(negative regulation of guanyl-nucleotide exchange factor activity)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|rcsb pdb:3U6H|rcsb pdb:3U6I|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|rcsb pdb:7V3R|rcsb pdb:7V3S|rcsb pdb:7Y4T|rcsb pdb:7Y4U|rcsb pdb:8AN8|rcsb pdb:8ANS|rcsb pdb:8AU3|rcsb pdb:8AU5|rcsb pdb:8AW1|rcsb pdb:8GVJ|rcsb pdb:8K78|rcsb pdb:8OUU|rcsb pdb:8OUV|rcsb pdb:8OV7|rcsb pdb:8OVZ|rcsb pdb:8OW3|rcsb pdb:8OWG|rcsb pdb:9C1R|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|reactome:R-HSA-9734091|reactome:R-HSA-9825892|refseq:NP_000236.2|refseq:NP_001120972.1|efo:""Orphanet:319298""|efo:""Orphanet:33402""|efo:""Orphanet:47044""|efo:""Orphanet:488265""|efo:""Orphanet:90636""|dip:DIP-6023N|panther:PTHR24416(orthology-group)"	mint:A0A0S2C3P2	-	-	-	figure legend:fig. 5a|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/05/21	2025/03/05	rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606	rogid:9TCJUx+Z9xQ/WI3syaoLpp++iIg210	intact-crc:DCE92FCF5E4473A1|rigid:1RIwkZvR9jpf65XIJv7iK5IbaiE	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0S2C3P2	uniprotkb:P12830	intact:EBI-55025805	intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|uniprotkb:Q9UII8|ensembl:ENSP00000261769.4	psi-mi:a0a0s2c3p2_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	psi-mi:cadh1_human(display_long)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Oliveira et al. (2009)	pubmed:19604117|imex:IM-30087	taxid:210(helpx)|taxid:210(Helicobacter pylori)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55025841	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:A0A0S2C3P2	"efo:""Orphanet:1331""|efo:""Orphanet:199306""|efo:""Orphanet:1997""|efo:""Orphanet:227535""|efo:""Orphanet:26106""|ensembl:ENSG00000039068.20(gene)|ensembl:ENST00000261769.10(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007416""(synapse assembly)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016339""(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0016600""(flotillin complex)|go:""GO:0021983""(pituitary gland development)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030057""(desmosome)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030506""(ankyrin binding)|go:""GO:0030517""(negative regulation of axon extension)|go:""GO:0031175""(neuron projection development)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071285""(cellular response to lithium ion)|go:""GO:0071503""(response to heparin)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099576""(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:""GO:0140459""(response to Gram-positive bacterium)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6VEL|rcsb pdb:7STZ|rcsb pdb:8H62|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|reactome:R-HSA-9823730|reactome:R-HSA-9856649|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|refseq:NP_004351.1|dip:DIP-477N|panther:PTHR24027(orthology-group)"	-	-	-	figure legend:fig. 5a|curation depth:imex curation	taxid:9606(human-nci-n87)|taxid:9606(Homo sapiens NCI-N87 gastric carcinoma cell)	-	2024/05/21	2025/03/18	rogid:9TCJUx+Z9xQ/WI3syaoLpp++iIg210	rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606	intact-crc:2550AC8CF7A63571|rigid:NFajG0/G+PcCqKx0l8IckzKNqS0	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:O60716	uniprotkb:A0A0S2C3P2	intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004.5	intact:EBI-55025805	"psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:""p120(cas)""(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym)"	psi-mi:a0a0s2c3p2_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Oliveira et al. (2009)	pubmed:19604117|imex:IM-30087	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:210(helpx)|taxid:210(Helicobacter pylori)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55025845	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000198561.16(gene)|ensembl:ENST00000399050.10(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009986""(cell surface)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016342""(catenin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030426""(growth cone)|go:""GO:0030496""(midbody)|go:""GO:0043197""(dendritic spine)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045296""(cadherin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098831""(presynaptic active zone cytoplasmic component)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0150107""(positive regulation of protein localization to cell-cell junction)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9833576|refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|efo:""Orphanet:1997""|dip:DIP-33850N|panther:PTHR10372(orthology-group)"	mint:A0A0S2C3P2	-	-	-	figure legend:fig. 5a|curation depth:imex curation	taxid:9606(human-nci-n87)|taxid:9606(Homo sapiens NCI-N87 gastric carcinoma cell)	-	2024/05/21	2025/02/28	rogid:HgMvbcDKedE291TIvIOqLFT3srw9606	rogid:9TCJUx+Z9xQ/WI3syaoLpp++iIg210	intact-crc:F907DABA101A2129|rigid:UXNZoBDx1b/21Y+3iSlfaD4OF5g	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P00519	uniprotkb:P55980	intact:EBI-375543|uniprotkb:Q13869|uniprotkb:Q13870|uniprotkb:Q16133|uniprotkb:Q45F09|uniprotkb:A3KFJ3|uniprotkb:Q17R61|intact:EBI-1550796|ensembl:ENSP00000323315.5	intact:EBI-528104	psi-mi:abl1_human(display_long)|uniprotkb:Abelson tyrosine-protein kinase 1(gene name synonym)|uniprotkb:ABL1(gene name)|psi-mi:ABL1(display_short)|uniprotkb:ABL(gene name synonym)|uniprotkb:JTK7(gene name synonym)|uniprotkb:Abelson murine leukemia viral oncogene homolog 1(gene name synonym)|uniprotkb:Proto-oncogene c-Abl(gene name synonym)|uniprotkb:p150(gene name synonym)	psi-mi:caga_helpy(display_long)|uniprotkb:120 kDa protein(gene name synonym)|uniprotkb:CAG pathogenicity island protein 26(gene name synonym)|uniprotkb:cai(gene name synonym)|uniprotkb:HP_0547(locus name)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:cag26(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Poppe et al. (2007)	pubmed:17160020|imex:IM-30088	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:85962(helpy)|taxid:85962(Helicobacter pylori)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55029461	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000097007.20(gene)|ensembl:ENST00000318560.6(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000400""(four-way junction DNA binding)|go:""GO:0000405""(bubble DNA binding)|go:""GO:0001726""(ruffle)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0001922""(B-1 B cell homeostasis)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002322""(B cell proliferation involved in immune response)|go:""GO:0002333""(transitional one stage B cell differentiation)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003785""(actin monomer binding)|go:""GO:0004515""(nicotinate-nucleotide adenylyltransferase activity)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006298""(mismatch repair)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006914""(autophagy)|go:""GO:0006974""(DNA damage response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008306""(associative learning)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016301""(kinase activity)|go:""GO:0016604""(nuclear body)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019905""(syntaxin binding)|go:""GO:0021587""(cerebellum morphogenesis)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030035""(microspike assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030516""(regulation of axon extension)|go:""GO:0030845""(phospholipase C-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0031113""(regulation of microtubule polymerization)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032489""(regulation of Cdc42 protein signal transduction)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035791""(platelet-derived growth factor receptor-beta signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0038191""(neuropilin binding)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0045580""(regulation of T cell differentiation)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046632""(alpha-beta T cell differentiation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050798""(activated T cell proliferation)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0051015""(actin filament binding)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051353""(positive regulation of oxidoreductase activity)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051444""(negative regulation of ubiquitin-protein transferase activity)|go:""GO:0051450""(myoblast proliferation)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051882""(mitochondrial depolarization)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060563""(neuroepithelial cell differentiation)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0070097""(delta-catenin binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071103""(DNA conformation change)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071871""(response to epinephrine)|go:""GO:0071901""(negative regulation of protein serine/threonine kinase activity)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090398""(cellular senescence)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099150""(regulation of postsynaptic specialization assembly)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900006""(positive regulation of dendrite development)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1900272""(negative regulation of long-term synaptic potentiation)|go:""GO:1902036""(regulation of hematopoietic stem cell differentiation)|go:""GO:1903055""(positive regulation of extracellular matrix organization)|go:""GO:1903210""(podocyte apoptotic process)|go:""GO:1903351""(cellular response to dopamine)|go:""GO:1903905""(positive regulation of establishment of T cell polarity)|go:""GO:1904157""(DN4 thymocyte differentiation)|go:""GO:1904518""(protein localization to cytoplasmic microtubule plus-end)|go:""GO:1904528""(positive regulation of microtubule binding)|go:""GO:1904531""(positive regulation of actin filament binding)|go:""GO:1905244""(regulation of modification of synaptic structure)|go:""GO:1905555""(positive regulation of blood vessel branching)|go:""GO:1990051""(activation of protein kinase C activity)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000096""(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|go:""GO:2000145""(regulation of cell motility)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000773""(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P00519|rcsb pdb:1AB2|rcsb pdb:1AWO|rcsb pdb:1BBZ|rcsb pdb:1JU5|rcsb pdb:1OPL|rcsb pdb:1ZZP|rcsb pdb:2ABL|rcsb pdb:2E2B|rcsb pdb:2F4J|rcsb pdb:2FO0|rcsb pdb:2G1T|rcsb pdb:2G2F|rcsb pdb:2G2H|rcsb pdb:2G2I|rcsb pdb:2GQG|rcsb pdb:2HIW|rcsb pdb:2HYY|rcsb pdb:2HZ0|rcsb pdb:2HZ4|rcsb pdb:2HZI|rcsb pdb:2O88|rcsb pdb:2V7A|rcsb pdb:3CS9|rcsb pdb:3EG0|rcsb pdb:3EG1|rcsb pdb:3EG2|rcsb pdb:3EG3|rcsb pdb:3EGU|rcsb pdb:3K2M|rcsb pdb:3PYY|rcsb pdb:3QRI|rcsb pdb:3QRJ|rcsb pdb:3QRK|rcsb pdb:3T04|rcsb pdb:3UE4|rcsb pdb:3UYO|rcsb pdb:4J9B|rcsb pdb:4J9C|rcsb pdb:4J9D|rcsb pdb:4J9E|rcsb pdb:4J9F|rcsb pdb:4J9G|rcsb pdb:4J9H|rcsb pdb:4J9I|rcsb pdb:4JJB|rcsb pdb:4JJC|rcsb pdb:4JJD|rcsb pdb:4TWP|rcsb pdb:4WA9|rcsb pdb:4XEY|rcsb pdb:4YC8|rcsb pdb:4ZOG|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5HU9|rcsb pdb:5MO4|rcsb pdb:5NP2|rcsb pdb:5OAZ|rcsb pdb:6AMV|rcsb pdb:6AMW|rcsb pdb:6BL8|rcsb pdb:6NPE|rcsb pdb:6NPU|rcsb pdb:6NPV|rcsb pdb:6XR6|rcsb pdb:6XR7|rcsb pdb:6XRG|rcsb pdb:7CC2|rcsb pdb:7DT2|rcsb pdb:7N9G|rcsb pdb:7PVQ|rcsb pdb:7PVR|rcsb pdb:7PVS|rcsb pdb:7PVV|rcsb pdb:7PW2|rcsb pdb:7W7X|rcsb pdb:7W7Y|rcsb pdb:8H7F|rcsb pdb:8H7H|rcsb pdb:8I7S|rcsb pdb:8I7T|rcsb pdb:8I7Z|rcsb pdb:8SSN|reactome:R-HSA-2029482|reactome:R-HSA-428890|reactome:R-HSA-525793|reactome:R-HSA-5663213|reactome:R-HSA-5685938|reactome:R-HSA-5693565|reactome:R-HSA-69231|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-9841922|reactome:R-HSA-9860927|refseq:NP_005148.2|refseq:NP_009297.2|efo:""Orphanet:521""|efo:""Orphanet:585909""|efo:""Orphanet:643503""|efo:""Orphanet:99861""|dip:DIP-1042N|panther:PTHR24418(orthology-group)"	"refseq:NP_207343.1|refseq:WP_000180747.1|go:""GO:0019534""(toxin transmembrane transporter activity)|go:""GO:0060090""(molecular adaptor activity)|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|rcsb pdb:3IEC|rcsb pdb:4DVY|rcsb pdb:4DVZ|rcsb pdb:4G0H|rcsb pdb:4IRV|rcsb pdb:5X7B|rcsb pdb:5X94|mint:P55980|dip:DIP-3093N|panther:PTHR34491(orthology-group)"	-	-	-	figure legend:fig. 3a|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/06/06	2024/11/14	rogid:t7dT+fWrrK2QaWF4U0HQaVgHKUc9606	rogid:zY/av87/S2z+icshOd5+yU6G5OI85962	intact-crc:AA0B35269DF5F1BD|rigid:wz+JlzBzeDlloz1Qxmo3q97TNgs	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P41240	uniprotkb:Q9F220	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003.9|ensembl:ENSP00000414764.2|ensembl:ENSP00000454906.1	intact:EBI-55027296	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	psi-mi:q9f220_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Tsutsumi et al. (2006)	pubmed:16354697|imex:IM-30148	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:210(helpx)|taxid:210(Helicobacter pylori)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55031117	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653.17(gene)|ensembl:ENST00000220003.14(transcript)|ensembl:ENST00000439220.6(transcript)|ensembl:ENST00000567571.5(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010989""(negative regulation of low-density lipoprotein particle clearance)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0042997""(negative regulation of Golgi to plasma membrane protein transport)|go:""GO:0045779""(negative regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369|panther:PTHR24418(orthology-group)|refseq:NP_001120662.1|refseq:NP_004374.1"	"go:""GO:0019534""(toxin transmembrane transporter activity)|mint:Q9F220|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	-	-	"comment:""\""can't find corrispondence for 2 mutant tyr residues: Y965A and Y999A described in reference 12391297\"""""	"figure legend:fig. 2c-d|comment:""\""can't find corrispondence for 2 mutant tyr residues: Y965A and Y999A described in reference 12391297\""""|curation depth:imex curation"	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/06/18	2024/11/14	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	rogid:DemGs7UHWSvVddEpkqqwg/rlw7c210	intact-crc:1574CE1F7F0DA03A|rigid:eUtSKfP2/rN8sEb8b5ONPgA5ErM	false	-	necessary binding region:868-940|mutation disrupting interaction:893-893,912-912,1023-1023|mutation disrupting interaction:912-912,893-893|ha tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q06124	uniprotkb:Q9F220	intact:EBI-297779|uniprotkb:Q96HD7|uniprotkb:A8K1D9|ensembl:ENSP00000340944.3|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	intact:EBI-55027296	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:q9f220_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Tsutsumi et al. (2006)	pubmed:16354697|imex:IM-30148	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:210(helpx)|taxid:210(Helicobacter pylori)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55032779	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2499""|efo:""Orphanet:500""|efo:""Orphanet:648""|efo:""Orphanet:86834""|ensembl:ENSG00000179295.19(gene)|ensembl:ENST00000351677.7(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007409""(axonogenesis)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0009755""(hormone-mediated signaling pathway)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021697""(cerebellar cortex formation)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030220""(platelet formation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031666""(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0032528""(microvillus organization)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0033629""(negative regulation of cell adhesion mediated by integrin)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035265""(organ growth)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0036302""(atrioventricular canal development)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0042445""(hormone metabolic process)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0045296""(cadherin binding)|go:""GO:0045778""(positive regulation of ossification)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0046676""(negative regulation of insulin secretion)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0046887""(positive regulation of hormone secretion)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048011""(neurotrophin TRK receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048806""(genitalia development)|go:""GO:0048839""(inner ear development)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051428""(peptide hormone receptor binding)|go:""GO:0051463""(negative regulation of cortisol secretion)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060125""(negative regulation of growth hormone secretion)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0061582""(intestinal epithelial cell migration)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:Q06124|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|rcsb pdb:4DGP|rcsb pdb:4DGX|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|rcsb pdb:5EHR|rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|rcsb pdb:7R75|rcsb pdb:7R7D|rcsb pdb:7R7I|rcsb pdb:7R7L|rcsb pdb:7RCT|rcsb pdb:7TVJ|rcsb pdb:7VXG|rcsb pdb:7XHQ|rcsb pdb:8B5Y|rcsb pdb:8CBH|rcsb pdb:8GWW|rcsb pdb:8RZW|rcsb pdb:8RZY|rcsb pdb:8S01|rcsb pdb:8S04|rcsb pdb:8S06|rcsb pdb:8S07|rcsb pdb:8S0H|rcsb pdb:8S0I|rcsb pdb:8S0J|rcsb pdb:8S0K|rcsb pdb:8S0O|rcsb pdb:8S0P|rcsb pdb:8S0Q|rcsb pdb:8S0S|rcsb pdb:8T6D|rcsb pdb:8T6G|rcsb pdb:8T7Q|rcsb pdb:8T8Q|rcsb pdb:8U7W|rcsb pdb:8U7X|rcsb pdb:8WFY|rcsb pdb:8WX7|rcsb pdb:9BLG|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6811558|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-9028731|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-936964|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9702518|reactome:R-HSA-9703648|reactome:R-HSA-9705671|refseq:NP_001317366.1|refseq:NP_002825.3|refseq:NP_542168.1|dip:DIP-516N|ensembl:ENSP00000340944.3|ensembl:ENST00000392597.5|ensembl:ENSP00000376376.1|ensembl:ENST00000635625.1|ensembl:ENSP00000489597.1|panther:PTHR46559(orthology-group)"	"go:""GO:0019534""(toxin transmembrane transporter activity)|mint:Q9F220|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	-	-	-	figure legend:fig. 4c|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/06/18	2024/11/14	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	rogid:DemGs7UHWSvVddEpkqqwg/rlw7c210	intact-crc:F46EE6724750EEF7|rigid:NSOFrj0bY67qibVAJKqpcFGZIP8	false	myc tag:?-?|mutation increasing interaction:459-459,425-425	ha tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P41240	uniprotkb:Q9F220	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003.9|ensembl:ENSP00000414764.2|ensembl:ENSP00000454906.1	intact:EBI-55027296	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	psi-mi:q9f220_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Tsutsumi et al. (2003)	pubmed:12446738|imex:IM-30090	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:210(helpx)|taxid:210(Helicobacter pylori)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55036921	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653.17(gene)|ensembl:ENST00000220003.14(transcript)|ensembl:ENST00000439220.6(transcript)|ensembl:ENST00000567571.5(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010989""(negative regulation of low-density lipoprotein particle clearance)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0042997""(negative regulation of Golgi to plasma membrane protein transport)|go:""GO:0045779""(negative regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369|panther:PTHR24418(orthology-group)|refseq:NP_001120662.1|refseq:NP_004374.1"	"go:""GO:0019534""(toxin transmembrane transporter activity)|mint:Q9F220|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	-	-	"comment:""\""can't find corrispondence for 2 mutant tyr residues: Y965A and Y999A\"""""	figure legend:fig. 1b; 2a|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2024/07/01	2024/11/14	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	rogid:DemGs7UHWSvVddEpkqqwg/rlw7c210	intact-crc:4F5863198B12957F|rigid:eUtSKfP2/rN8sEb8b5ONPgA5ErM	false	myc tag:?-?	mutation disrupting interaction:1023-1023,912-912,893-893|ha tag:?-?|mutation decreasing interaction:912-912,893-893	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9F220	uniprotkb:P41240	intact:EBI-55027296	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003.9|ensembl:ENSP00000414764.2|ensembl:ENSP00000454906.1	psi-mi:q9f220_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Tsutsumi et al. (2003)	pubmed:12446738|imex:IM-30090	taxid:210(helpx)|taxid:210(Helicobacter pylori)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55036981	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0019534""(toxin transmembrane transporter activity)|mint:Q9F220|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	"refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653.17(gene)|ensembl:ENST00000220003.14(transcript)|ensembl:ENST00000439220.6(transcript)|ensembl:ENST00000567571.5(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010989""(negative regulation of low-density lipoprotein particle clearance)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0042997""(negative regulation of Golgi to plasma membrane protein transport)|go:""GO:0045779""(negative regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369|panther:PTHR24418(orthology-group)|refseq:NP_001120662.1|refseq:NP_004374.1"	-	"comment:""\""can't find corrispondence for 2 mutant tyr residues: Y965A and Y999A\"""""	-	figure legend:fig. 1c|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/07/01	2024/11/14	rogid:DemGs7UHWSvVddEpkqqwg/rlw7c210	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	intact-crc:42652C52F9A5DBC3|rigid:eUtSKfP2/rN8sEb8b5ONPgA5ErM	false	mutation disrupting interaction:1023-1023,893-893,912-912|ha tag:?-?	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:B5Z6S0	uniprotkb:Q96QB1-2	intact:EBI-7287204|intact:MINT-7297600	intact:EBI-55037838|ensembl:ENSP00000276297.4	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	psi-mi:q96qb1-2(display_long)|uniprotkb:HP protein(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Hinsenkamp et al. (2022)	pubmed:35963849|imex:IM-30153	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55037676	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149"	ensembl:ENSG00000164741.15(gene)|ensembl:ENST00000276297.9(transcript)|intact:EBI-2608428(isoform-parent)	"go:""GO:0005925""(focal adhesion)"	comment:mint	-	"figure legend:fig. 4|comment:""\""DLC1 was localised to the periphery of spread-out cells and in  focal adhesions (DLCv1) or neurite-like extensions (DLC1v4),  whereas CagA was targeted to the plasma membrane and  promoted needle-like cell elongations (“humming bird”).\""""|curation depth:imex curation"	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/07/01	2024/11/14	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606	intact-crc:2549792FDC1D2E50|rigid:ZVJ8N0yhYyUJ3nXSZ7wtnZ2XwCM	false	enhanced green fluorescent protein tag:n-n	flag tag:n-n	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q96QB1-4	uniprotkb:B5Z6S0	intact:EBI-55037686|ensembl:ENSP00000428028.1	intact:EBI-7287204|intact:MINT-7297600	psi-mi:q96qb1-4(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:HP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Hinsenkamp et al. (2022)	pubmed:35963849|imex:IM-30153	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55037716	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	ensembl:ENSG00000164741.15(gene)|ensembl:ENST00000520226.5(transcript)|intact:EBI-2608428(isoform-parent)	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149"	"go:""GO:0031253""(cell projection membrane)"	-	comment:mint	"figure legend:fig. 4|comment:""\""DLC1 was localised to the periphery of spread-out cells and in  focal adhesions (DLCv1) or neurite-like extensions (DLC1v4),  whereas CagA was targeted to the plasma membrane and  promoted needle-like cell elongations (“humming bird”).\""""|curation depth:imex curation"	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/07/01	2024/11/14	rogid:eCAkh+ap3pSomHmdcop+SK/s+Yw9606	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	intact-crc:C96FB961DB984CAE|rigid:kGGc+JaHjGXYMwUPZrWPaSq9xWI	false	flag tag:n-n	enhanced green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q96QB1-2	uniprotkb:B5Z6S0	intact:EBI-55037838|ensembl:ENSP00000276297.4	intact:EBI-7287204|intact:MINT-7297600	psi-mi:q96qb1-2(display_long)|uniprotkb:HP protein(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	"psi-mi:""MI:0813""(proximity ligation assay)"	Hinsenkamp et al. (2022)	pubmed:35963849|imex:IM-30153	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55037732	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	ensembl:ENSG00000164741.15(gene)|ensembl:ENST00000276297.9(transcript)|intact:EBI-2608428(isoform-parent)	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149"	-	-	comment:mint	figure legend:fig.6d|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2024/07/01	2024/11/14	rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	intact-crc:814803CE091AD934|rigid:ZVJ8N0yhYyUJ3nXSZ7wtnZ2XwCM	false	-	green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q96QB1-4	uniprotkb:B5Z6S0	intact:EBI-55037686|ensembl:ENSP00000428028.1	intact:EBI-7287204|intact:MINT-7297600	psi-mi:q96qb1-4(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:HP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	"psi-mi:""MI:0813""(proximity ligation assay)"	Hinsenkamp et al. (2022)	pubmed:35963849|imex:IM-30153	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55037816	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	ensembl:ENSG00000164741.15(gene)|ensembl:ENST00000520226.5(transcript)|intact:EBI-2608428(isoform-parent)	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149"	-	-	comment:mint	figure legend:fig.6d|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2024/07/01	2024/11/14	rogid:eCAkh+ap3pSomHmdcop+SK/s+Yw9606	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	intact-crc:8DC134306BE83CAC|rigid:kGGc+JaHjGXYMwUPZrWPaSq9xWI	false	-	green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q96QB1-2	uniprotkb:B5Z6S0	intact:EBI-55037838|ensembl:ENSP00000276297.4	intact:EBI-7287204|intact:MINT-7297600	psi-mi:q96qb1-2(display_long)|uniprotkb:HP protein(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Hinsenkamp et al. (2022)	pubmed:35963849|imex:IM-30153	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55037830	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	ensembl:ENSG00000164741.15(gene)|ensembl:ENST00000276297.9(transcript)|intact:EBI-2608428(isoform-parent)	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149"	-	-	comment:mint	figure legend:fig. 6b|comment:Both N- and C-terminal  parts of FL CagA interacted with the two DLC1 isoforms.|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2024/07/01	2024/11/14	rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	intact-crc:F25696E3A7C946BE|rigid:ZVJ8N0yhYyUJ3nXSZ7wtnZ2XwCM	false	-	binding-associated region:838-1216,1-877	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q96QB1-4	uniprotkb:B5Z6S0	intact:EBI-55037686|ensembl:ENSP00000428028.1	intact:EBI-7287204|intact:MINT-7297600	psi-mi:q96qb1-4(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:HP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Hinsenkamp et al. (2022)	pubmed:35963849|imex:IM-30153	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55037848	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	ensembl:ENSG00000164741.15(gene)|ensembl:ENST00000520226.5(transcript)|intact:EBI-2608428(isoform-parent)	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149"	-	-	comment:mint	figure legend:fig. 6b|comment:Both N- and C-terminal  parts of FL CagA interacted with the two DLC1 isoforms.|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2024/07/01	2024/11/14	rogid:eCAkh+ap3pSomHmdcop+SK/s+Yw9606	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	intact-crc:6026BFCE50A3DE42|rigid:kGGc+JaHjGXYMwUPZrWPaSq9xWI	false	-	binding-associated region:838-1216,1-877	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:C6K4R4	uniprotkb:P62258	intact:EBI-55031236	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335.8|ensembl:ENSP00000487356.1	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	"psi-mi:""MI:0018""(two hybrid)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042836	intact-miscore:0.64	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	"efo:""Orphanet:213711""|efo:""Orphanet:217385""|efo:""Orphanet:261257""|efo:""Orphanet:457246""|efo:""Orphanet:531""|dip:DIP-36676N|ensembl:ENSG00000108953.17(gene)|ensembl:ENSG00000274474.3(gene)|ensembl:ENST00000264335.13(transcript)|ensembl:ENST00000627231.2(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001764""(neuron migration)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003064""(regulation of heart rate by hormone)|go:""GO:0003723""(RNA binding)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008104""(protein localization)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0060306""(regulation of membrane repolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|go:""GO:1905913""(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|rcsb pdb:7V9B|rcsb pdb:8DGM|rcsb pdb:8DGN|rcsb pdb:8DGP|rcsb pdb:8DP5|rcsb pdb:8Q1S|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_006752.1|panther:PTHR18860(orthology-group)|ensembl:ENSP00000264335.8|ensembl:ENST00000571732.5|ensembl:ENSP00000461762.1|ensembl:ENST00000616643.3|ensembl:ENSP00000481059.2|ensembl:ENSP00000487356.1"	-	-	-	figure legend:fig.1|curation depth:imex curation	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2024/07/08	2025/03/21	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	intact-crc:F18DF4FD39055467|rigid:lHUUKbOEjhb34f3k1v099AJS6z0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:C6K4R4	uniprotkb:P68104	intact:EBI-55031236	intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|ensembl:ENSP00000330054.2|ensembl:ENSP00000339053.4|ensembl:ENSP00000339063.7|ensembl:ENSP00000348651.3|ensembl:ENSP00000392366.2|ensembl:ENSP00000479055.2|ensembl:ENSP00000503192.1|ensembl:ENSP00000503249.1|ensembl:ENSP00000503823.1|ensembl:ENSP00000504335.1|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|intact:EBI-16423274	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042841	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	"ensembl:ENSG00000156508.19(gene)|ensembl:ENST00000309268.11(transcript)|ensembl:ENST00000316292.13(transcript)|ensembl:ENST00000331523.7(transcript)|ensembl:ENST00000356303.7(transcript)|ensembl:ENST00000455918.2(transcript)|ensembl:ENST00000615060.5(transcript)|ensembl:ENST00000676710.1(transcript)|ensembl:ENST00000677236.1(transcript)|ensembl:ENST00000678508.1(transcript)|ensembl:ENST00000678702.1(transcript)|mint:P68104|rcsb pdb:3C5J|go:""GO:0000049""(tRNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005853""(eukaryotic translation elongation factor 1 complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006412""(translation)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0019209""(kinase activator activity)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0032587""(ruffle membrane)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0098574""(cytoplasmic side of lysosomal membrane)|go:""GO:1904714""(regulation of chaperone-mediated autophagy)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR050100|interpro:IPR054696|rcsb pdb:6ZMO|rcsb pdb:8G60|rcsb pdb:8G6J|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|reactome:R-HSA-9735869|refseq:XP_011533816.1|dip:DIP-31277N|refseq:NP_001393.1|panther:PTHR23115(orthology-group)"	-	-	-	figure legend:fig.1|curation depth:imex curation	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2024/07/08	2025/03/26	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606	intact-crc:9697924956E15630|rigid:zj47hjCK0n556Y1QTm2sfMMe5Vo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:C6K4R4	uniprotkb:P60709	intact:EBI-55031236	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|ensembl:ENSP00000494269.1|ensembl:ENSP00000494750.1|ensembl:ENSP00000495995.2|ensembl:ENSP00000501862.1|ensembl:ENSP00000502821.1|uniprotkb:Q96HG5	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042845	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	"efo:""Orphanet:673556""|efo:""Orphanet:674653""|ensembl:ENSG00000075624.17(gene)|ensembl:ENST00000493945.6(transcript)|ensembl:ENST00000642480.2(transcript)|ensembl:ENST00000646664.1(transcript)|ensembl:ENST00000674681.1(transcript)|ensembl:ENST00000675515.1(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0000786""(nucleosome)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007409""(axonogenesis)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019894""(kinesin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0022898""(regulation of transmembrane transporter activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030424""(axon)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0035060""(brahma complex)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045176""(apical protein localization)|go:""GO:0045202""(synapse)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048156""(tau protein binding)|go:""GO:0048870""(cell motility)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051621""(regulation of norepinephrine uptake)|go:""GO:0051623""(positive regulation of norepinephrine uptake)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070160""(tight junction)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071564""(npBAF complex)|go:""GO:0071565""(nBAF complex)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0072562""(blood microparticle)|go:""GO:0072749""(cellular response to cytochalasin B)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140092""(bBAF complex)|go:""GO:0140288""(GBAF complex)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000779""(regulation of double-strand break repair)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|rcsb pdb:7P1H|rcsb pdb:7QJ6|rcsb pdb:7QJ9|rcsb pdb:7VDV|rcsb pdb:7W28|rcsb pdb:7W29|rcsb pdb:7Y8R|rcsb pdb:7ZTC|rcsb pdb:7ZTD|rcsb pdb:8COG|rcsb pdb:8DNH|rcsb pdb:8IB8|rcsb pdb:8OI8|rcsb pdb:8OID|rcsb pdb:8QR1|rcsb pdb:8RTT|rcsb pdb:8RTY|rcsb pdb:8RU2|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|rcsb pdb:8XVT|rcsb pdb:9C57|rcsb pdb:9C62|rcsb pdb:9C6N|rcsb pdb:9FJM|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-9824585|reactome:R-HSA-983231|reactome:R-HSA-9845323|refseq:NP_001092.1|efo:""Orphanet:2995""|efo:""Orphanet:64755""|efo:""Orphanet:79107""|dip:DIP-29686N|panther:PTHR11937(orthology-group)"	-	-	-	figure legend:fig.1|curation depth:imex curation	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2024/07/08	2025/02/27	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	intact-crc:2BF0FEE9EA7F07B5|rigid:ks4c+HkSF7a9nGoQfURfLp9rDJw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:C6K4R4	uniprotkb:P0DJD8	intact:EBI-55031236	intact:EBI-54801832|ensembl:ENSP00000322192.6|uniprotkb:A8K749|uniprotkb:B2R7D6|uniprotkb:B7ZW75|uniprotkb:P00790|uniprotkb:Q7M4R0|uniprotkb:Q8N1E3	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	psi-mi:pepa3_human(display_long)|uniprotkb:PGA3(gene name)|psi-mi:PGA3(display_short)|uniprotkb:Pepsinogen-3(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042849	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	"ensembl:ENSG00000229859.10(gene)|ensembl:ENST00000325558.11(transcript)|go:""GO:0004190""(aspartic-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0007586""(digestion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097486""(multivesicular body lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR034162|reactome:R-HSA-5683826|panther:PTHR47966(orthology-group)|refseq:NP_001073275.1"	-	-	-	figure legend:fig.1|curation depth:imex curation	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2024/07/08	2024/11/15	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	rogid:c27/km44pTUFBfq8IhM2g8DxFiE9606	intact-crc:4AA9834AB855F614|rigid:Gla7wSk6OA9rN0OvrSaDX5UvkXs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:C6K4R4	intact:EBI-55042856	intact:EBI-55031236	-	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	psi-mi:synthetic construct hypothetical protein gene(display_short)|psi-mi:EBI-55042856(display_long)	"psi-mi:""MI:0018""(two hybrid)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042853	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0327""(peptide)"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	-	-	-	-	figure legend:fig.1|curation depth:imex curation	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2024/07/08	2024/11/15	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	rogid:d6nVufTJC6PkQ3ZLSibsZy+BsnI9606	intact-crc:9408D73006BBB576|rigid:DCdt2gXsKBfc05hjpHsuSm8zUk0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62258	uniprotkb:C6K4R4	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335.8|ensembl:ENSP00000487356.1	intact:EBI-55031236	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0096""(pull down)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042896	intact-miscore:0.64	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:213711""|efo:""Orphanet:217385""|efo:""Orphanet:261257""|efo:""Orphanet:457246""|efo:""Orphanet:531""|dip:DIP-36676N|ensembl:ENSG00000108953.17(gene)|ensembl:ENSG00000274474.3(gene)|ensembl:ENST00000264335.13(transcript)|ensembl:ENST00000627231.2(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001764""(neuron migration)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003064""(regulation of heart rate by hormone)|go:""GO:0003723""(RNA binding)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008104""(protein localization)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0060306""(regulation of membrane repolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|go:""GO:1905913""(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|rcsb pdb:7V9B|rcsb pdb:8DGM|rcsb pdb:8DGN|rcsb pdb:8DGP|rcsb pdb:8DP5|rcsb pdb:8Q1S|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_006752.1|panther:PTHR18860(orthology-group)|ensembl:ENSP00000264335.8|ensembl:ENST00000571732.5|ensembl:ENSP00000461762.1|ensembl:ENST00000616643.3|ensembl:ENSP00000481059.2|ensembl:ENSP00000487356.1"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	-	-	-	figure legend:fig. 2|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2024/07/08	2025/03/21	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	intact-crc:698C2DCE36FFFF61|rigid:lHUUKbOEjhb34f3k1v099AJS6z0	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0833""(autoradiography)"	"psi-mi:""MI:0833""(autoradiography)"
uniprotkb:P62258	uniprotkb:C6K4R4	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335.8|ensembl:ENSP00000487356.1	intact:EBI-55031236	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042909	intact-miscore:0.64	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:213711""|efo:""Orphanet:217385""|efo:""Orphanet:261257""|efo:""Orphanet:457246""|efo:""Orphanet:531""|dip:DIP-36676N|ensembl:ENSG00000108953.17(gene)|ensembl:ENSG00000274474.3(gene)|ensembl:ENST00000264335.13(transcript)|ensembl:ENST00000627231.2(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001764""(neuron migration)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003064""(regulation of heart rate by hormone)|go:""GO:0003723""(RNA binding)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008104""(protein localization)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0060306""(regulation of membrane repolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|go:""GO:1905913""(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|rcsb pdb:7V9B|rcsb pdb:8DGM|rcsb pdb:8DGN|rcsb pdb:8DGP|rcsb pdb:8DP5|rcsb pdb:8Q1S|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_006752.1|panther:PTHR18860(orthology-group)|ensembl:ENSP00000264335.8|ensembl:ENST00000571732.5|ensembl:ENSP00000461762.1|ensembl:ENST00000616643.3|ensembl:ENSP00000481059.2|ensembl:ENSP00000487356.1"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	-	-	-	figure legend:fig. 3a|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/07/08	2025/03/21	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	intact-crc:35D249E6CFC27D68|rigid:lHUUKbOEjhb34f3k1v099AJS6z0	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P62258	uniprotkb:C6K4R4	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335.8|ensembl:ENSP00000487356.1	intact:EBI-55031236	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042918	intact-miscore:0.64	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:213711""|efo:""Orphanet:217385""|efo:""Orphanet:261257""|efo:""Orphanet:457246""|efo:""Orphanet:531""|dip:DIP-36676N|ensembl:ENSG00000108953.17(gene)|ensembl:ENSG00000274474.3(gene)|ensembl:ENST00000264335.13(transcript)|ensembl:ENST00000627231.2(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001764""(neuron migration)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003064""(regulation of heart rate by hormone)|go:""GO:0003723""(RNA binding)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008104""(protein localization)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0060306""(regulation of membrane repolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|go:""GO:1905913""(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|rcsb pdb:7V9B|rcsb pdb:8DGM|rcsb pdb:8DGN|rcsb pdb:8DGP|rcsb pdb:8DP5|rcsb pdb:8Q1S|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_006752.1|panther:PTHR18860(orthology-group)|ensembl:ENSP00000264335.8|ensembl:ENST00000571732.5|ensembl:ENSP00000461762.1|ensembl:ENST00000616643.3|ensembl:ENSP00000481059.2|ensembl:ENSP00000487356.1"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	-	-	-	figure legend:fig. 3a|curation depth:imex curation	taxid:9606(human-sgc7901)|taxid:9606(Homo sapiens SGC7901 gastric cancer cell)	-	2024/07/08	2025/03/21	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	intact-crc:983D16782C4E2204|rigid:lHUUKbOEjhb34f3k1v099AJS6z0	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:C6K4R4	uniprotkb:P62258	intact:EBI-55031236	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335.8|ensembl:ENSP00000487356.1	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042956	intact-miscore:0.64	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	"efo:""Orphanet:213711""|efo:""Orphanet:217385""|efo:""Orphanet:261257""|efo:""Orphanet:457246""|efo:""Orphanet:531""|dip:DIP-36676N|ensembl:ENSG00000108953.17(gene)|ensembl:ENSG00000274474.3(gene)|ensembl:ENST00000264335.13(transcript)|ensembl:ENST00000627231.2(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001764""(neuron migration)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003064""(regulation of heart rate by hormone)|go:""GO:0003723""(RNA binding)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008104""(protein localization)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0060306""(regulation of membrane repolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|go:""GO:1905913""(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|rcsb pdb:7V9B|rcsb pdb:8DGM|rcsb pdb:8DGN|rcsb pdb:8DGP|rcsb pdb:8DP5|rcsb pdb:8Q1S|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_006752.1|panther:PTHR18860(orthology-group)|ensembl:ENSP00000264335.8|ensembl:ENST00000571732.5|ensembl:ENSP00000461762.1|ensembl:ENST00000616643.3|ensembl:ENSP00000481059.2|ensembl:ENSP00000487356.1"	-	-	-	figure legend:fig. 3b|curation depth:imex curation	taxid:9606(human-sgc7901)|taxid:9606(Homo sapiens SGC7901 gastric cancer cell)	-	2024/07/08	2025/03/21	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	intact-crc:81ECEEBC5CBC2EBF|rigid:lHUUKbOEjhb34f3k1v099AJS6z0	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:C6K4R4	uniprotkb:P62258	intact:EBI-55031236	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335.8|ensembl:ENSP00000487356.1	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042965	intact-miscore:0.64	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	"efo:""Orphanet:213711""|efo:""Orphanet:217385""|efo:""Orphanet:261257""|efo:""Orphanet:457246""|efo:""Orphanet:531""|dip:DIP-36676N|ensembl:ENSG00000108953.17(gene)|ensembl:ENSG00000274474.3(gene)|ensembl:ENST00000264335.13(transcript)|ensembl:ENST00000627231.2(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001764""(neuron migration)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003064""(regulation of heart rate by hormone)|go:""GO:0003723""(RNA binding)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008104""(protein localization)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0060306""(regulation of membrane repolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|go:""GO:1905913""(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|rcsb pdb:7V9B|rcsb pdb:8DGM|rcsb pdb:8DGN|rcsb pdb:8DGP|rcsb pdb:8DP5|rcsb pdb:8Q1S|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_006752.1|panther:PTHR18860(orthology-group)|ensembl:ENSP00000264335.8|ensembl:ENST00000571732.5|ensembl:ENSP00000461762.1|ensembl:ENST00000616643.3|ensembl:ENSP00000481059.2|ensembl:ENSP00000487356.1"	-	-	-	figure legend:fig. 3c|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2024/07/08	2025/03/21	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	intact-crc:5892DB82FD87E7E3|rigid:lHUUKbOEjhb34f3k1v099AJS6z0	false	flag tag:?-?	myc tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P62258	uniprotkb:C6K4R4	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335.8|ensembl:ENSP00000487356.1	intact:EBI-55031236	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:c6k4r4_helpx(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Zhang et al. (2018)	pubmed:29106533|imex:IM-30157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)|taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-55042978	intact-miscore:0.64	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:213711""|efo:""Orphanet:217385""|efo:""Orphanet:261257""|efo:""Orphanet:457246""|efo:""Orphanet:531""|dip:DIP-36676N|ensembl:ENSG00000108953.17(gene)|ensembl:ENSG00000274474.3(gene)|ensembl:ENST00000264335.13(transcript)|ensembl:ENST00000627231.2(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001764""(neuron migration)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003064""(regulation of heart rate by hormone)|go:""GO:0003723""(RNA binding)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008104""(protein localization)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0060306""(regulation of membrane repolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|go:""GO:1905913""(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|rcsb pdb:7V9B|rcsb pdb:8DGM|rcsb pdb:8DGN|rcsb pdb:8DGP|rcsb pdb:8DP5|rcsb pdb:8Q1S|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_006752.1|panther:PTHR18860(orthology-group)|ensembl:ENSP00000264335.8|ensembl:ENST00000571732.5|ensembl:ENSP00000461762.1|ensembl:ENST00000616643.3|ensembl:ENSP00000481059.2|ensembl:ENSP00000487356.1"	"go:""GO:0019534""(toxin transmembrane transporter activity)|refseq:WP_000180734.1|interpro:IPR005169(CagA exotoxin)|interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)"	-	-	-	figure legend:fig. 3d|curation depth:imex curation	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2024/07/08	2025/03/21	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:3aknJt43oIyXZWHK8kRjI/cfF54102618	intact-crc:FFA32CE5B16846EF|rigid:lHUUKbOEjhb34f3k1v099AJS6z0	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:M4NKV9	uniprotkb:Q14332	intact:EBI-20596828	intact:EBI-6254477|uniprotkb:Q0VG82|ensembl:ENSP00000323901.3	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	psi-mi:fzd2_human(display_long)|uniprotkb:FZD2(gene name)|psi-mi:FZD2(display_short)|uniprotkb:FzE2(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20596877|imex:IM-28267-1	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	"ensembl:ENSG00000180340.7(gene)|ensembl:ENST00000315323.5(transcript)|go:""GO:0003149""(membranous septum morphogenesis)|go:""GO:0003150""(muscular septum morphogenesis)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0045446""(endothelial cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060022""(hard palate development)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060119""(inner ear receptor cell development)|go:""GO:0090103""(cochlea morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR041778|mint:Q14332|rcsb pdb:6C0B|rcsb pdb:7N95|rcsb pdb:7N97|rcsb pdb:7N9S|rcsb pdb:7X8P|reactome:R-HSA-201681|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641262|reactome:R-HSA-5140745|refseq:NP_001457.1|efo:""Orphanet:3107""|efo:""Orphanet:93328""|panther:PTHR11309(orthology-group)"	-	-	-	figure legend:Figure 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	rogid:xUZEXv3xJwlICF+75aayCbVPEpM9606	intact-crc:110E14E51A99403E|rigid:5qAznzZ++pMkCqI0/JLiXerkxAQ	false	binding-associated region:1285-1804(6C0B)	his tag:n-n|binding-associated region:24-156	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:M4NKV9	uniprotkb:Q14332	intact:EBI-20596828	intact:EBI-6254477|uniprotkb:Q0VG82|ensembl:ENSP00000323901.3	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	psi-mi:fzd2_human(display_long)|uniprotkb:FZD2(gene name)|psi-mi:FZD2(display_short)|uniprotkb:FzE2(gene name synonym)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20596916|imex:IM-28267-5	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	"ensembl:ENSG00000180340.7(gene)|ensembl:ENST00000315323.5(transcript)|go:""GO:0003149""(membranous septum morphogenesis)|go:""GO:0003150""(muscular septum morphogenesis)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0045446""(endothelial cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060022""(hard palate development)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060119""(inner ear receptor cell development)|go:""GO:0090103""(cochlea morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR041778|mint:Q14332|rcsb pdb:6C0B|rcsb pdb:7N95|rcsb pdb:7N97|rcsb pdb:7N9S|rcsb pdb:7X8P|reactome:R-HSA-201681|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641262|reactome:R-HSA-5140745|refseq:NP_001457.1|efo:""Orphanet:3107""|efo:""Orphanet:93328""|panther:PTHR11309(orthology-group)"	-	-	-	figure legend:Figure S1, 4E, 4F, S7B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.3x10^-8(molar)	2018/06/18	2024/11/14	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	rogid:xUZEXv3xJwlICF+75aayCbVPEpM9606	intact-crc:34F4A2E5581EB002|rigid:5qAznzZ++pMkCqI0/JLiXerkxAQ	false	binding-associated region:1285-1804|mutation decreasing interaction strength:1502-1502|mutation decreasing interaction strength:1510-1510,1512-1512|mutation decreasing interaction strength:1510-1510,1600-1600|mutation decreasing interaction strength:1434-1434|mutation disrupting interaction strength:1598-1598|mutation disrupting interaction strength:1598-1598|mutation disrupting interaction strength:1438-1438,1494-1494|mutation disrupting interaction strength:1434-1434,1438-1438,1494-1494|necessary binding region:1596-1601	fc-igg tag:c-c|binding-associated region:29-168	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:M4NKV9	uniprotkb:Q13467	intact:EBI-20596828	intact:EBI-3913027|uniprotkb:Q53R22|uniprotkb:A8K2X1|uniprotkb:B2RCZ1|intact:EBI-28987270|ensembl:ENSP00000354607.3	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	psi-mi:fzd5_human(display_long)|uniprotkb:FZD5(gene name)|psi-mi:FZD5(display_short)|uniprotkb:C2orf31(gene name synonym)|uniprotkb:FzE5(gene name synonym)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20622487|imex:IM-28267-7	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	"ensembl:ENSG00000163251.4(gene)|ensembl:ENST00000295417.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000578""(embryonic axis specification)|go:""GO:0001525""(angiogenesis)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001654""(eye development)|go:""GO:0002071""(glandular epithelial cell maturation)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007416""(synapse assembly)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008289""(lipid binding)|go:""GO:0008595""(anterior/posterior axis specification, embryo)|go:""GO:0009986""(cell surface)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031077""(post-embryonic camera-type eye development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0043204""(perikaryon)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045202""(synapse)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048596""(embryonic camera-type eye morphogenesis)|go:""GO:0060061""(Spemann organizer formation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060561""(apoptotic process involved in morphogenesis)|go:""GO:0060574""(intestinal epithelial cell maturation)|go:""GO:0060670""(branching involved in labyrinthine layer morphogenesis)|go:""GO:0060715""(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0060718""(chorionic trophoblast cell differentiation)|go:""GO:0071219""(cellular response to molecule of bacterial origin)|go:""GO:1901382""(regulation of chorionic trophoblast cell proliferation)|go:""GO:1901524""(regulation of mitophagy)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR037441|mint:Q13467|rcsb pdb:5URY|rcsb pdb:5URZ|rcsb pdb:6O39|rcsb pdb:6WW2|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641262|reactome:R-HSA-4641263|reactome:R-HSA-5140745|reactome:R-HSA-5340588|refseq:NP_003459.2|efo:""Orphanet:98942""|efo:""Orphanet:98943""|efo:""Orphanet:98944""|efo:""Orphanet:98945""|efo:""Orphanet:98946""|efo:""Orphanet:98947""|panther:PTHR11309(orthology-group)"	-	-	-	figure legend:Figure 4D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	rogid:MoGzsWpiGoqv/NtqWfqL9ZmJXyA9606	intact-crc:C37B2D4D94CEB7CE|rigid:SAXoi7FF3KvNoZno4d8Z6DzvFME	false	mutation decreasing interaction:1598-1598|ha tag:c-c|binding-associated region:1285-1804	his tag:c-c|binding-associated region:1-167|fc-igg tag:c-c	1	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14332	uniprotkb:M4NKV9	intact:EBI-6254477|uniprotkb:Q0VG82|ensembl:ENSP00000323901.3	intact:EBI-20596828	psi-mi:fzd2_human(display_long)|uniprotkb:FZD2(gene name)|psi-mi:FZD2(display_short)|uniprotkb:FzE2(gene name synonym)	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20622495|imex:IM-28267-9	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000180340.7(gene)|ensembl:ENST00000315323.5(transcript)|go:""GO:0003149""(membranous septum morphogenesis)|go:""GO:0003150""(muscular septum morphogenesis)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0045446""(endothelial cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060022""(hard palate development)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060119""(inner ear receptor cell development)|go:""GO:0090103""(cochlea morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR041778|mint:Q14332|rcsb pdb:6C0B|rcsb pdb:7N95|rcsb pdb:7N97|rcsb pdb:7N9S|rcsb pdb:7X8P|reactome:R-HSA-201681|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641262|reactome:R-HSA-5140745|refseq:NP_001457.1|efo:""Orphanet:3107""|efo:""Orphanet:93328""|panther:PTHR11309(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	-	-	-	figure legend:Figure 4E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:xUZEXv3xJwlICF+75aayCbVPEpM9606	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	intact-crc:82327DF327BB59EE|rigid:5qAznzZ++pMkCqI0/JLiXerkxAQ	false	fc-igg tag:c-c|binding-associated region:29-168	ha tag:c-c|binding-associated region:1285-1804	-	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9ULV1	uniprotkb:M4NKV9	intact:EBI-2466380|uniprotkb:A8K9Q3|uniprotkb:Q14C97|uniprotkb:Q6S9E4|ensembl:ENSP00000434034.1	intact:EBI-20596828	psi-mi:fzd4_human(display_long)|uniprotkb:FZD4(gene name)|psi-mi:FZD4(display_short)|uniprotkb:FzE4(gene name synonym)	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20638294|imex:IM-28267-11	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000174804.4(gene)|ensembl:ENST00000531380.2(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0007223""(Wnt signaling pathway, calcium modulating pathway)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030947""(regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031987""(locomotion involved in locomotory behavior)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035426""(extracellular matrix-cell signaling)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042701""(progesterone secretion)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045446""(endothelial cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050775""(positive regulation of dendrite morphogenesis)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060856""(establishment of blood-brain barrier)|go:""GO:0061299""(retina vasculature morphogenesis in camera-type eye)|go:""GO:0061301""(cerebellum vasculature morphogenesis)|go:""GO:0061304""(retinal blood vessel morphogenesis)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0110135""(Norrin signaling pathway)|go:""GO:0150012""(positive regulation of neuron projection arborization)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026551|interpro:IPR036790|interpro:IPR041765|mint:Q9ULV1|rcsb pdb:5BPB|rcsb pdb:5BPQ|rcsb pdb:5BQC|rcsb pdb:5BQE|rcsb pdb:5CL1|rcsb pdb:5CM4|rcsb pdb:5UWG|rcsb pdb:6BD4|rcsb pdb:6NE1|rcsb pdb:8WM9|rcsb pdb:8WMA|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641263|reactome:R-HSA-5099900|reactome:R-HSA-5340588|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_036325.2|efo:""Orphanet:891""|efo:""Orphanet:90050""|efo:""Orphanet:91495""|panther:PTHR11309(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	-	-	-	figure legend:Fig S6A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:AMa+JdoYYdqHGs85YaqVNE+YGAY9606	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	intact-crc:986DC6CA1FE30ABF|rigid:+8rx4GXsZonB9mZ0MlcHDBFsoIk	false	binding-associated region:1-180|fc-igg tag:c-c	ha tag:c-c|binding-associated region:1285-1804	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H461	uniprotkb:M4NKV9	intact:EBI-6254212|ensembl:ENSP00000363826.1	intact:EBI-20596828	psi-mi:fzd8_human(display_long)|uniprotkb:FZD8(gene name)|psi-mi:FZD8(display_short)	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20638306|imex:IM-28267-13	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_114072.1|ensembl:ENSG00000177283.8(gene)|ensembl:ENST00000374694.3(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0098992""(neuronal dense core vesicle)|go:""GO:1990851""(Wnt-Frizzled-LRP5/6 complex)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR041776|rcsb pdb:5UN5|rcsb pdb:5UN6|rcsb pdb:6NDZ|rcsb pdb:8X0T|reactome:R-HSA-373080|reactome:R-HSA-4608870|reactome:R-HSA-4641263|reactome:R-HSA-5340588|panther:PTHR11309(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	-	-	-	figure legend:Fig S6B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:4b66+WyB0ZsLi6KV5Rvcprf4jj49606	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	intact-crc:2018003FF6290341|rigid:3G25VFjs2r20Q3gd753ClsFeo1E	false	binding-associated region:25-172|fc-igg tag:c-c	binding-associated region:1285-1804|ha tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O00144	uniprotkb:M4NKV9	intact:EBI-20638318|ensembl:ENSP00000345785.3	intact:EBI-20596828	psi-mi:fzd9_human(display_long)|uniprotkb:FZD9(gene name)|psi-mi:FZD9(display_short)|uniprotkb:FZD3(gene name synonym)|uniprotkb:FzE6(gene name synonym)	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20638368|imex:IM-28267-15	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000188763.5(gene)|ensembl:ENST00000344575.5(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0007399""(nervous system development)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007611""(learning or memory)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030501""(positive regulation of bone mineralization)|go:""GO:0031527""(filopodium membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051902""(negative regulation of mitochondrial depolarization)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099173""(postsynapse organization)|go:""GO:0099566""(regulation of postsynaptic cytosolic calcium ion concentration)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1904393""(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:""GO:1904394""(negative regulation of skeletal muscle acetylcholine-gated channel clustering)|go:""GO:1990523""(bone regeneration)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|reactome:R-HSA-373080|refseq:NP_003499.1|panther:PTHR11309(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	-	-	-	figure legend:Fig S6C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:FhuOYWyfG8Sg1Aq3rGZLLZudbQA9606	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	intact-crc:96A8AA6969844C43|rigid:bLi/C+yq1om3qTyA/0tjMoiDLTI	false	binding-associated region:23-185|fc-igg tag:c-c	binding-associated region:1285-1804|ha tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P18177	uniprotkb:Q13467	intact:EBI-8536569|uniprotkb:M4NW36|intact:MINT-2634250	intact:EBI-3913027|uniprotkb:Q53R22|uniprotkb:A8K2X1|uniprotkb:B2RCZ1|intact:EBI-28987270|ensembl:ENSP00000354607.3	psi-mi:tcdb_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)	psi-mi:fzd5_human(display_long)|uniprotkb:FZD5(gene name)|psi-mi:FZD5(display_short)|uniprotkb:C2orf31(gene name synonym)|uniprotkb:FzE5(gene name synonym)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20638379|imex:IM-28267-17	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046527""(glucosyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|rcsb pdb:2BVL|rcsb pdb:2BVM|rcsb pdb:4NC2|rcsb pdb:4NP4|rcsb pdb:5UQM|rcsb pdb:5UQN|rcsb pdb:5UQT|rcsb pdb:6AR6|rcsb pdb:6C0B|rcsb pdb:6OQ5|rcsb pdb:6OQ6|rcsb pdb:6OQ7|rcsb pdb:6OQ8|rcsb pdb:7LOU|rcsb pdb:7LOV|rcsb pdb:7ML7|rcsb pdb:7N8X|rcsb pdb:7N95|rcsb pdb:7N97|rcsb pdb:7N9Q|rcsb pdb:7N9R|rcsb pdb:7N9S|rcsb pdb:7N9Y|rcsb pdb:7S0Y|rcsb pdb:7SO5|rcsb pdb:7SO7|rcsb pdb:8QEN|rcsb pdb:8QEO|rcsb pdb:8Y9B|rcsb pdb:9BJA|refseq:WP_009902069.1|interpro:IPR024770|interpro:IPR020974|interpro:IPR018337|interpro:IPR024772|interpro:IPR024769|interpro:IPR029044|interpro:IPR038383|mint:P18177"	"ensembl:ENSG00000163251.4(gene)|ensembl:ENST00000295417.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000578""(embryonic axis specification)|go:""GO:0001525""(angiogenesis)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001654""(eye development)|go:""GO:0002071""(glandular epithelial cell maturation)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007416""(synapse assembly)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008289""(lipid binding)|go:""GO:0008595""(anterior/posterior axis specification, embryo)|go:""GO:0009986""(cell surface)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031077""(post-embryonic camera-type eye development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0043204""(perikaryon)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045202""(synapse)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048596""(embryonic camera-type eye morphogenesis)|go:""GO:0060061""(Spemann organizer formation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060561""(apoptotic process involved in morphogenesis)|go:""GO:0060574""(intestinal epithelial cell maturation)|go:""GO:0060670""(branching involved in labyrinthine layer morphogenesis)|go:""GO:0060715""(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0060718""(chorionic trophoblast cell differentiation)|go:""GO:0071219""(cellular response to molecule of bacterial origin)|go:""GO:1901382""(regulation of chorionic trophoblast cell proliferation)|go:""GO:1901524""(regulation of mitophagy)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR037441|mint:Q13467|rcsb pdb:5URY|rcsb pdb:5URZ|rcsb pdb:6O39|rcsb pdb:6WW2|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641262|reactome:R-HSA-4641263|reactome:R-HSA-5140745|reactome:R-HSA-5340588|refseq:NP_003459.2|efo:""Orphanet:98942""|efo:""Orphanet:98943""|efo:""Orphanet:98944""|efo:""Orphanet:98945""|efo:""Orphanet:98946""|efo:""Orphanet:98947""|panther:PTHR11309(orthology-group)"	-	comment:mint|function:Cytotoxin	-	figure legend:Fig S6D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:K4BbX+DMm7uUt0CrM1ONCFqaPwc1496	rogid:MoGzsWpiGoqv/NtqWfqL9ZmJXyA9606	intact-crc:173441085FA06ED5|rigid:s8WeHIfoobqhDmg0HUEmnyLJa2U	false	his tag:n-n	binding-associated region:1-167|his tag:c-c|fc-igg tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P18177	uniprotkb:Q14332	intact:EBI-8536569|uniprotkb:M4NW36|intact:MINT-2634250	intact:EBI-6254477|uniprotkb:Q0VG82|ensembl:ENSP00000323901.3	psi-mi:tcdb_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)	psi-mi:fzd2_human(display_long)|uniprotkb:FZD2(gene name)|psi-mi:FZD2(display_short)|uniprotkb:FzE2(gene name synonym)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20638392|imex:IM-28267-19	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046527""(glucosyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|rcsb pdb:2BVL|rcsb pdb:2BVM|rcsb pdb:4NC2|rcsb pdb:4NP4|rcsb pdb:5UQM|rcsb pdb:5UQN|rcsb pdb:5UQT|rcsb pdb:6AR6|rcsb pdb:6C0B|rcsb pdb:6OQ5|rcsb pdb:6OQ6|rcsb pdb:6OQ7|rcsb pdb:6OQ8|rcsb pdb:7LOU|rcsb pdb:7LOV|rcsb pdb:7ML7|rcsb pdb:7N8X|rcsb pdb:7N95|rcsb pdb:7N97|rcsb pdb:7N9Q|rcsb pdb:7N9R|rcsb pdb:7N9S|rcsb pdb:7N9Y|rcsb pdb:7S0Y|rcsb pdb:7SO5|rcsb pdb:7SO7|rcsb pdb:8QEN|rcsb pdb:8QEO|rcsb pdb:8Y9B|rcsb pdb:9BJA|refseq:WP_009902069.1|interpro:IPR024770|interpro:IPR020974|interpro:IPR018337|interpro:IPR024772|interpro:IPR024769|interpro:IPR029044|interpro:IPR038383|mint:P18177"	"ensembl:ENSG00000180340.7(gene)|ensembl:ENST00000315323.5(transcript)|go:""GO:0003149""(membranous septum morphogenesis)|go:""GO:0003150""(muscular septum morphogenesis)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0045446""(endothelial cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060022""(hard palate development)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060119""(inner ear receptor cell development)|go:""GO:0090103""(cochlea morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR041778|mint:Q14332|rcsb pdb:6C0B|rcsb pdb:7N95|rcsb pdb:7N97|rcsb pdb:7N9S|rcsb pdb:7X8P|reactome:R-HSA-201681|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641262|reactome:R-HSA-5140745|refseq:NP_001457.1|efo:""Orphanet:3107""|efo:""Orphanet:93328""|panther:PTHR11309(orthology-group)"	-	comment:mint|function:Cytotoxin	-	figure legend:Fig S7A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:K4BbX+DMm7uUt0CrM1ONCFqaPwc1496	rogid:xUZEXv3xJwlICF+75aayCbVPEpM9606	intact-crc:34AEEFD010C4F743|rigid:S9wnd6JJiP/6kDZ3e72y4HByMTY	false	his tag:n-n	binding-associated region:29-168|fc-igg tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:M4NKV9	uniprotkb:Q14332	intact:EBI-20596828	intact:EBI-6254477|uniprotkb:Q0VG82|ensembl:ENSP00000323901.3	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	psi-mi:fzd2_human(display_long)|uniprotkb:FZD2(gene name)|psi-mi:FZD2(display_short)|uniprotkb:FzE2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20596893|wwpdb:6C0B|imex:IM-28267-3	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	"ensembl:ENSG00000180340.7(gene)|ensembl:ENST00000315323.5(transcript)|go:""GO:0003149""(membranous septum morphogenesis)|go:""GO:0003150""(muscular septum morphogenesis)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0045446""(endothelial cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060022""(hard palate development)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060119""(inner ear receptor cell development)|go:""GO:0090103""(cochlea morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR041778|mint:Q14332|rcsb pdb:6C0B|rcsb pdb:7N95|rcsb pdb:7N97|rcsb pdb:7N9S|rcsb pdb:7X8P|reactome:R-HSA-201681|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641262|reactome:R-HSA-5140745|refseq:NP_001457.1|efo:""Orphanet:3107""|efo:""Orphanet:93328""|panther:PTHR11309(orthology-group)"	-	-	-	figure legend:Fig S3A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	rogid:xUZEXv3xJwlICF+75aayCbVPEpM9606	intact-crc:04849118E60147BF|rigid:5qAznzZ++pMkCqI0/JLiXerkxAQ	false	ha tag:c-c|binding-associated region:1285-1804|mutation disrupting interaction strength:1598-1598|mutation disrupting interaction strength:1598-1598|necessary binding region:1596-1601|mutation disrupting interaction strength:1438-1438,1494-1494|mutation disrupting interaction strength:1434-1434,1438-1438,1494-1494	his tag:n-n|binding-associated region:24-156	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:M4NKV9	uniprotkb:Q13467	intact:EBI-20596828	intact:EBI-3913027|uniprotkb:Q53R22|uniprotkb:A8K2X1|uniprotkb:B2RCZ1|intact:EBI-28987270|ensembl:ENSP00000354607.3	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	psi-mi:fzd5_human(display_long)|uniprotkb:FZD5(gene name)|psi-mi:FZD5(display_short)|uniprotkb:C2orf31(gene name synonym)|uniprotkb:FzE5(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20597926|imex:IM-28267-21	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	"ensembl:ENSG00000163251.4(gene)|ensembl:ENST00000295417.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000578""(embryonic axis specification)|go:""GO:0001525""(angiogenesis)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001654""(eye development)|go:""GO:0002071""(glandular epithelial cell maturation)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007416""(synapse assembly)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008289""(lipid binding)|go:""GO:0008595""(anterior/posterior axis specification, embryo)|go:""GO:0009986""(cell surface)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031077""(post-embryonic camera-type eye development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0043204""(perikaryon)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045202""(synapse)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048596""(embryonic camera-type eye morphogenesis)|go:""GO:0060061""(Spemann organizer formation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060561""(apoptotic process involved in morphogenesis)|go:""GO:0060574""(intestinal epithelial cell maturation)|go:""GO:0060670""(branching involved in labyrinthine layer morphogenesis)|go:""GO:0060715""(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0060718""(chorionic trophoblast cell differentiation)|go:""GO:0071219""(cellular response to molecule of bacterial origin)|go:""GO:1901382""(regulation of chorionic trophoblast cell proliferation)|go:""GO:1901524""(regulation of mitophagy)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR037441|mint:Q13467|rcsb pdb:5URY|rcsb pdb:5URZ|rcsb pdb:6O39|rcsb pdb:6WW2|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641262|reactome:R-HSA-4641263|reactome:R-HSA-5140745|reactome:R-HSA-5340588|refseq:NP_003459.2|efo:""Orphanet:98942""|efo:""Orphanet:98943""|efo:""Orphanet:98944""|efo:""Orphanet:98945""|efo:""Orphanet:98946""|efo:""Orphanet:98947""|panther:PTHR11309(orthology-group)"	-	-	-	figure legend:Figure 4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	rogid:MoGzsWpiGoqv/NtqWfqL9ZmJXyA9606	intact-crc:659B6EE6E8500D0C|rigid:SAXoi7FF3KvNoZno4d8Z6DzvFME	false	ha tag:c-c	his tag:c-c|binding-associated region:1-167|fc-igg tag:c-c	1	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13467	uniprotkb:M4NKV9	intact:EBI-3913027|uniprotkb:Q53R22|uniprotkb:A8K2X1|uniprotkb:B2RCZ1|intact:EBI-28987270|ensembl:ENSP00000354607.3	intact:EBI-20596828	psi-mi:fzd5_human(display_long)|uniprotkb:FZD5(gene name)|psi-mi:FZD5(display_short)|uniprotkb:C2orf31(gene name synonym)|uniprotkb:FzE5(gene name synonym)	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	"psi-mi:""MI:0096""(pull down)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20620246|wwpdb:6C0B|imex:IM-28267-23	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000163251.4(gene)|ensembl:ENST00000295417.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000578""(embryonic axis specification)|go:""GO:0001525""(angiogenesis)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001654""(eye development)|go:""GO:0002071""(glandular epithelial cell maturation)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007416""(synapse assembly)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008289""(lipid binding)|go:""GO:0008595""(anterior/posterior axis specification, embryo)|go:""GO:0009986""(cell surface)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031077""(post-embryonic camera-type eye development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0043204""(perikaryon)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045202""(synapse)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048596""(embryonic camera-type eye morphogenesis)|go:""GO:0060061""(Spemann organizer formation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060561""(apoptotic process involved in morphogenesis)|go:""GO:0060574""(intestinal epithelial cell maturation)|go:""GO:0060670""(branching involved in labyrinthine layer morphogenesis)|go:""GO:0060715""(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0060718""(chorionic trophoblast cell differentiation)|go:""GO:0071219""(cellular response to molecule of bacterial origin)|go:""GO:1901382""(regulation of chorionic trophoblast cell proliferation)|go:""GO:1901524""(regulation of mitophagy)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR037441|mint:Q13467|rcsb pdb:5URY|rcsb pdb:5URZ|rcsb pdb:6O39|rcsb pdb:6WW2|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641262|reactome:R-HSA-4641263|reactome:R-HSA-5140745|reactome:R-HSA-5340588|refseq:NP_003459.2|efo:""Orphanet:98942""|efo:""Orphanet:98943""|efo:""Orphanet:98944""|efo:""Orphanet:98945""|efo:""Orphanet:98946""|efo:""Orphanet:98947""|panther:PTHR11309(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	-	-	-	figure legend:Figure 4C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2025/02/26	rogid:MoGzsWpiGoqv/NtqWfqL9ZmJXyA9606	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	intact-crc:835DDF81C6986A61|rigid:hNAHiZWNumP/z1tyY0gVFRdkjLk	false	his tag:c-c|binding-associated region:1-180|fc-igg tag:c-c	binding-associated region:1285-1804|ha tag:c-c	-	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:M4NKV9	uniprotkb:Q14332	intact:EBI-20596828	intact:EBI-6254477|uniprotkb:Q0VG82|ensembl:ENSP00000323901.3	psi-mi:m4nkv9_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:KRQ00_003159(orf name)	psi-mi:fzd2_human(display_long)|uniprotkb:FZD2(gene name)|psi-mi:FZD2(display_short)|uniprotkb:FzE2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Chen et al. (2018)	pubmed:29748286|imex:IM-28267	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20638999|imex:IM-28267-27	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR020972|refseq:WP_003426838.1|interpro:IPR018337|interpro:IPR020974|interpro:IPR038383|interpro:IPR029044|interpro:IPR024770|interpro:IPR024772|interpro:IPR024769|rcsb pdb:6OQ5"	"ensembl:ENSG00000180340.7(gene)|ensembl:ENST00000315323.5(transcript)|go:""GO:0003149""(membranous septum morphogenesis)|go:""GO:0003150""(muscular septum morphogenesis)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0045446""(endothelial cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060022""(hard palate development)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060119""(inner ear receptor cell development)|go:""GO:0090103""(cochlea morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|interpro:IPR041778|mint:Q14332|rcsb pdb:6C0B|rcsb pdb:7N95|rcsb pdb:7N97|rcsb pdb:7N9S|rcsb pdb:7X8P|reactome:R-HSA-201681|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4608870|reactome:R-HSA-4641262|reactome:R-HSA-5140745|refseq:NP_001457.1|efo:""Orphanet:3107""|efo:""Orphanet:93328""|panther:PTHR11309(orthology-group)"	-	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/06/18	2024/11/14	rogid:9gud/OIj33uLwj0LHaIxUAhMo641496	rogid:xUZEXv3xJwlICF+75aayCbVPEpM9606	intact-crc:A188BFA12A27F096|rigid:5qAznzZ++pMkCqI0/JLiXerkxAQ	false	ha tag:c-c|sufficient binding region:1285-1804|necessary binding region:1285-1429	his tag:n-n|binding-associated region:24-156	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:P04003	uniprotkb:P13050	intact:EBI-978348|ensembl:ENSP00000356037.3|uniprotkb:Q5VVQ8	intact:EBI-978341	psi-mi:c4bpa_human(display_long)|uniprotkb:Proline-rich protein(gene name synonym)|uniprotkb:C4BPA(gene name)|psi-mi:C4BPA(display_short)|uniprotkb:C4BP(gene name synonym)	psi-mi:arp4_strpy(display_long)|uniprotkb:arp4(gene name)|psi-mi:arp4(display_short)	"psi-mi:""MI:0440""(saturation binding)"	Jenkins et al. (2006)	imex:IM-14429|pubmed:16330538	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-978355|imex:IM-14429-1	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000123838.11(gene)|ensembl:ENST00000367070.8(transcript)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009609""(response to symbiotic bacterium)|go:""GO:0045087""(innate immune response)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0072562""(blood microparticle)|go:""GO:1903027""(regulation of opsonization)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR040514|interpro:IPR050350|rcsb pdb:2A55|rcsb pdb:4B0F|rcsb pdb:5HYP|rcsb pdb:5HYT|rcsb pdb:5HYU|rcsb pdb:5HZP|rcsb pdb:5I0Q|rcsb pdb:8TGT|reactome:R-HSA-977606|refseq:NP_000706.1|refseq:XP_005273308.1|refseq:XP_005273309.1|panther:PTHR19325(orthology-group)"	"interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR019950|interpro:IPR003345(M protein repeat)|go:""GO:0005576""(extracellular region)|rcsb pdb:8SKV|interpro:IPR049895|interpro:IPR049896|interpro:IPR019931"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Figure 1A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/27	2024/11/14	rogid:S0F99wuDTalS4UCuYGWbiCgWlO09606	rogid:k/bn+U+qgTKG8umFVeV2s9f1ZaU1314	intact-crc:0FD32F7161C05132|rigid:9KcGrpn6AACB/+g+KhHoC6DZOyo	false	sufficient binding region:1-62	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P13050	uniprotkb:P04003	intact:EBI-978341	intact:EBI-978348|ensembl:ENSP00000356037.3|uniprotkb:Q5VVQ8	psi-mi:arp4_strpy(display_long)|uniprotkb:arp4(gene name)|psi-mi:arp4(display_short)	psi-mi:c4bpa_human(display_long)|uniprotkb:Proline-rich protein(gene name synonym)|uniprotkb:C4BPA(gene name)|psi-mi:C4BPA(display_short)|uniprotkb:C4BP(gene name synonym)	"psi-mi:""MI:0440""(saturation binding)"	Jenkins et al. (2006)	imex:IM-14429|pubmed:16330538	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-978362|imex:IM-14429-2	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR019950|interpro:IPR003345(M protein repeat)|go:""GO:0005576""(extracellular region)|rcsb pdb:8SKV|interpro:IPR049895|interpro:IPR049896|interpro:IPR019931"	"ensembl:ENSG00000123838.11(gene)|ensembl:ENST00000367070.8(transcript)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009609""(response to symbiotic bacterium)|go:""GO:0045087""(innate immune response)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0072562""(blood microparticle)|go:""GO:1903027""(regulation of opsonization)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR040514|interpro:IPR050350|rcsb pdb:2A55|rcsb pdb:4B0F|rcsb pdb:5HYP|rcsb pdb:5HYT|rcsb pdb:5HYU|rcsb pdb:5HZP|rcsb pdb:5I0Q|rcsb pdb:8TGT|reactome:R-HSA-977606|refseq:NP_000706.1|refseq:XP_005273308.1|refseq:XP_005273309.1|panther:PTHR19325(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Figure 1A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/27	2024/11/14	rogid:k/bn+U+qgTKG8umFVeV2s9f1ZaU1314	rogid:S0F99wuDTalS4UCuYGWbiCgWlO09606	intact-crc:B61613174CE699FD|rigid:9KcGrpn6AACB/+g+KhHoC6DZOyo	false	-	sufficient binding region:63-124	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P13050	uniprotkb:P04003	intact:EBI-978341	intact:EBI-978348|ensembl:ENSP00000356037.3|uniprotkb:Q5VVQ8	psi-mi:arp4_strpy(display_long)|uniprotkb:arp4(gene name)|psi-mi:arp4(display_short)	psi-mi:c4bpa_human(display_long)|uniprotkb:Proline-rich protein(gene name synonym)|uniprotkb:C4BPA(gene name)|psi-mi:C4BPA(display_short)|uniprotkb:C4BP(gene name synonym)	"psi-mi:""MI:0440""(saturation binding)"	Jenkins et al. (2006)	imex:IM-14429|pubmed:16330538	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-978395|imex:IM-14429-3	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR019950|interpro:IPR003345(M protein repeat)|go:""GO:0005576""(extracellular region)|rcsb pdb:8SKV|interpro:IPR049895|interpro:IPR049896|interpro:IPR019931"	"ensembl:ENSG00000123838.11(gene)|ensembl:ENST00000367070.8(transcript)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009609""(response to symbiotic bacterium)|go:""GO:0045087""(innate immune response)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0072562""(blood microparticle)|go:""GO:1903027""(regulation of opsonization)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR040514|interpro:IPR050350|rcsb pdb:2A55|rcsb pdb:4B0F|rcsb pdb:5HYP|rcsb pdb:5HYT|rcsb pdb:5HYU|rcsb pdb:5HZP|rcsb pdb:5I0Q|rcsb pdb:8TGT|reactome:R-HSA-977606|refseq:NP_000706.1|refseq:XP_005273308.1|refseq:XP_005273309.1|panther:PTHR19325(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Figure 1B|comment:Insertion of two alanine residues between Lysine 188 and Isoleucine 189 resulted in abolished interaction between the two proteins.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/27	2024/11/14	rogid:k/bn+U+qgTKG8umFVeV2s9f1ZaU1314	rogid:S0F99wuDTalS4UCuYGWbiCgWlO09606	intact-crc:2485E33C6C8C57D8|rigid:9KcGrpn6AACB/+g+KhHoC6DZOyo	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P13050	uniprotkb:P04003	intact:EBI-978341	intact:EBI-978348|ensembl:ENSP00000356037.3|uniprotkb:Q5VVQ8	psi-mi:arp4_strpy(display_long)|uniprotkb:arp4(gene name)|psi-mi:arp4(display_short)	psi-mi:c4bpa_human(display_long)|uniprotkb:Proline-rich protein(gene name synonym)|uniprotkb:C4BPA(gene name)|psi-mi:C4BPA(display_short)|uniprotkb:C4BP(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Jenkins et al. (2006)	imex:IM-14429|pubmed:16330538	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-978429|imex:IM-14429-4	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR019950|interpro:IPR003345(M protein repeat)|go:""GO:0005576""(extracellular region)|rcsb pdb:8SKV|interpro:IPR049895|interpro:IPR049896|interpro:IPR019931"	"ensembl:ENSG00000123838.11(gene)|ensembl:ENST00000367070.8(transcript)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009609""(response to symbiotic bacterium)|go:""GO:0045087""(innate immune response)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0072562""(blood microparticle)|go:""GO:1903027""(regulation of opsonization)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR040514|interpro:IPR050350|rcsb pdb:2A55|rcsb pdb:4B0F|rcsb pdb:5HYP|rcsb pdb:5HYT|rcsb pdb:5HYU|rcsb pdb:5HZP|rcsb pdb:5I0Q|rcsb pdb:8TGT|reactome:R-HSA-977606|refseq:NP_000706.1|refseq:XP_005273308.1|refseq:XP_005273309.1|panther:PTHR19325(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Figure 1C|comment:A dimer of the APR4 protein was created as previous studies had shown that dimerization strongly enhanced C4BP binding. The APR4 protein used in this stidy also had a C-terminal Cys added.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/27	2024/11/14	rogid:k/bn+U+qgTKG8umFVeV2s9f1ZaU1314	rogid:S0F99wuDTalS4UCuYGWbiCgWlO09606	intact-crc:4D751B51215D362C|rigid:9KcGrpn6AACB/+g+KhHoC6DZOyo	false	sufficient binding region:1-45	his tag:c-c|sufficient binding region:1-124	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13050	uniprotkb:P04003	intact:EBI-978341	intact:EBI-978348|ensembl:ENSP00000356037.3|uniprotkb:Q5VVQ8	psi-mi:arp4_strpy(display_long)|uniprotkb:arp4(gene name)|psi-mi:arp4(display_short)	psi-mi:c4bpa_human(display_long)|uniprotkb:Proline-rich protein(gene name synonym)|uniprotkb:C4BPA(gene name)|psi-mi:C4BPA(display_short)|uniprotkb:C4BP(gene name synonym)	"psi-mi:""MI:0077""(nuclear magnetic resonance)"	Jenkins et al. (2006)	imex:IM-14429|pubmed:16330538	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-978544|imex:IM-14429-5	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR019950|interpro:IPR003345(M protein repeat)|go:""GO:0005576""(extracellular region)|rcsb pdb:8SKV|interpro:IPR049895|interpro:IPR049896|interpro:IPR019931"	"ensembl:ENSG00000123838.11(gene)|ensembl:ENST00000367070.8(transcript)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009609""(response to symbiotic bacterium)|go:""GO:0045087""(innate immune response)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0072562""(blood microparticle)|go:""GO:1903027""(regulation of opsonization)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR040514|interpro:IPR050350|rcsb pdb:2A55|rcsb pdb:4B0F|rcsb pdb:5HYP|rcsb pdb:5HYT|rcsb pdb:5HYU|rcsb pdb:5HZP|rcsb pdb:5I0Q|rcsb pdb:8TGT|reactome:R-HSA-977606|refseq:NP_000706.1|refseq:XP_005273308.1|refseq:XP_005273309.1|panther:PTHR19325(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Figure 4 and Figure 5|comment:The APR4 protein was present as a dimer.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/27	2024/11/14	rogid:k/bn+U+qgTKG8umFVeV2s9f1ZaU1314	rogid:S0F99wuDTalS4UCuYGWbiCgWlO09606	intact-crc:27B901077BE2F998|rigid:9KcGrpn6AACB/+g+KhHoC6DZOyo	false	sufficient binding region:1-45	sufficient binding region:49-172	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43318	uniprotkb:B5Z6S0	intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335.3	intact:EBI-7287204|intact:MINT-7297600	psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym)	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Lamb et al. (2009)	pubmed:19820695|imex:IM-13889|mint:MINT-7297592|doi:10.1038/embor.2009.210	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7287198|mint:MINT-7297626|imex:IM-13889-6	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000135341.19(gene)|ensembl:ENST00000369329.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0005114""(type II transforming growth factor beta receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007252""(I-kappaB phosphorylation)|go:""GO:0007254""(JNK cascade)|go:""GO:0008349""(MAP kinase kinase kinase kinase activity)|go:""GO:0010008""(endosome membrane)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0034138""(toll-like receptor 3 signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035173""(histone kinase activity)|go:""GO:0035666""(TRIF-dependent toll-like receptor signaling pathway)|go:""GO:0035872""(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0038172""(interleukin-33-mediated signaling pathway)|go:""GO:0038173""(interleukin-17A-mediated signaling pathway)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043276""(anoikis)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045793""(positive regulation of cell size)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140672""(ATAC complex)|go:""GO:0141111""(positive regulation of cGAS/STING signaling pathway)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904754""(positive regulation of vascular associated smooth muscle cell migration)|go:""GO:1990450""(linear polyubiquitin binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR049637|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|rcsb pdb:8GW3|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-9705671|reactome:R-HSA-975163|refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|dip:DIP-27523N|efo:""Orphanet:1826""|efo:""Orphanet:3238""|panther:PTHR46716(orthology-group)|mint:MINT-7297629(identity)"	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149|mint:MINT-7297628(identity)"	-	-	comment:mint	figure legend:f4a|comment:mint|comment:TAK1 taxid has not been specified.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2009/11/09	2025/03/31	rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	intact-crc:36FAFD55DF39A5A2|rigid:Eop0w7MCyzjFKIwOZY0Wnpo3OF8	false	ha tag:?-?(MINT-7297631)	flag tag:?-?(MINT-7297635)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q5NI40	uniprotkb:O00560	intact:EBI-2796048	intact:EBI-727004|uniprotkb:O43391|uniprotkb:O00173|uniprotkb:Q14CP2|ensembl:ENSP00000260130.4|ensembl:ENSP00000411771.2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:q5ni40_fratt(display_long)|uniprotkb:ppdK(gene name)|psi-mi:ppdK(display_short)|uniprotkb:FTT_0250(locus name)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2796052|imex:IM-13779-1	author score:14|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169302.1|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR018274|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR023151|interpro:IPR002192(Pyruvate phosphate dikinase, PEP/pyruvate-binding)|interpro:IPR010121(Pyruvate, phosphate dikinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR040442|interpro:IPR036637|go:""GO:0005524""(ATP binding)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0050242""(pyruvate, phosphate dikinase activity)"	"ensembl:ENSG00000137575.12(gene)|ensembl:ENST00000260130.9(transcript)|ensembl:ENST00000413219.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0005109""(frizzled binding)|go:""GO:0005137""(interleukin-5 receptor binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005895""(interleukin-5 receptor complex)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016020""(membrane)|go:""GO:0019838""(growth factor binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042043""(neurexin family protein binding)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045545""(syndecan binding)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0098793""(presynapse)|go:""GO:0099054""(presynapse assembly)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051230|mint:O00560|rcsb pdb:1N99|rcsb pdb:1NTE|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|rcsb pdb:7FSG|rcsb pdb:7FSH|rcsb pdb:7FSI|rcsb pdb:7FSJ|rcsb pdb:7FSK|rcsb pdb:7FSL|rcsb pdb:7FT5|rcsb pdb:7FSM|rcsb pdb:7FSN|rcsb pdb:7FSO|rcsb pdb:7FSP|rcsb pdb:7FSQ|rcsb pdb:7FSR|rcsb pdb:7FSS|rcsb pdb:7FST|rcsb pdb:7FSU|rcsb pdb:7FSV|rcsb pdb:7FSW|rcsb pdb:7FSX|rcsb pdb:7FSY|rcsb pdb:7FSZ|rcsb pdb:7FT0|rcsb pdb:7FT1|rcsb pdb:7FT2|rcsb pdb:7FT3|rcsb pdb:7FT4|rcsb pdb:7FT6|rcsb pdb:7FT7|rcsb pdb:7FT8|rcsb pdb:7FT9|rcsb pdb:7FTA|rcsb pdb:7FTB|rcsb pdb:7FTC|rcsb pdb:7FTD|rcsb pdb:8AAI|rcsb pdb:8AAK|rcsb pdb:8AAO|rcsb pdb:8AAP|rcsb pdb:8BLU|rcsb pdb:8BLV|rcsb pdb:8HCK|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-6798695|refseq:NP_001007068.1|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|dip:DIP-42705N|panther:PTHR12345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:lPu2TgwGa8adgnlyO6g7UzHr7Ns177416	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	intact-crc:1DD8EE3D56DAAAB1|rigid:i4OOGMP3C8IIAwvB3eFr5pt5bqA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96CN9	uniprotkb:Q5NFM9	intact:EBI-746252|ensembl:ENSP00000318821.2|uniprotkb:Q9H6N7	intact:EBI-2796076|uniprotkb:A0A0G2RQ49	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	psi-mi:q5nfm9_fratt(display_long)|uniprotkb:FTT_1204c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2796073|imex:IM-13779-2	author score:13|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000179562.3(gene)|ensembl:ENST00000321407.3(transcript)|go:""GO:0000138""(Golgi trans cisterna)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0031267""(small GTPase binding)|interpro:IPR000237(GRIP)|interpro:IPR051952|mint:Q96CN9|reactome:R-HSA-6811440|refseq:NP_078799.2|panther:PTHR23157(orthology-group)"	"refseq:YP_170163.1|refseq:WP_011242274.1|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	rogid:J2DDYYNUu1adkU/nx6bFbYc6VGs177416	intact-crc:51C3DFE4E7B69D05|rigid:tTwi1Cv5d9IAR5nNixBbLm2lzrg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIH4	uniprotkb:Q9UI68	intact:EBI-2796063|uniprotkb:A0A0G2RN86	intact:EBI-2796059	psi-mi:q5nih4_fratt(display_long)|uniprotkb:FTT_0096(locus name)	psi-mi:q9ui68_human(display_long)|uniprotkb:hCG_2022564(orf name)|uniprotkb:POLQ(gene name)|psi-mi:POLQ(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2796066|imex:IM-13779-3	author score:14|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003806(ATP-grasp fold, DUF201-type)|refseq:YP_169168.1|refseq:WP_003023028.1|go:""GO:0005524""(ATP binding)|go:""GO:0046872""(metal ion binding)"	"go:""GO:0005524""(ATP binding)|interpro:IPR046931"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kzHWI6x935nh0ewUsvlLQDaEY1A177416	rogid:Ps8cocit89Otks35gq7UCbj1F0g9606	intact-crc:42D8ABD546527555|rigid:Vl2SYNl2nuFbH/BPd5Fp+u5pyEM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17947	uniprotkb:Q5NGN4	intact:EBI-2293548|ensembl:ENSP00000367799.4|intact:EBI-28980694	intact:EBI-2796097|uniprotkb:A0A0G2RNF7	psi-mi:spi1_human(display_long)|uniprotkb:SPI1(gene name)|psi-mi:SPI1(display_short)|uniprotkb:31 kDa-transforming protein(gene name synonym)	psi-mi:q5ngn4_fratt(display_long)|uniprotkb:FTT_0801c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2796094|imex:IM-13779-6	author score:11|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000066336.13(gene)|ensembl:ENST00000378538.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001216""(DNA-binding transcription activator activity)|go:""GO:0001217""(DNA-binding transcription repressor activity)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002572""(pro-T cell differentiation)|go:""GO:0002573""(myeloid leukocyte differentiation)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043314""(negative regulation of neutrophil degranulation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045579""(positive regulation of B cell differentiation)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051090""(regulation of DNA-binding transcription factor activity)|go:""GO:0051525""(NFAT protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0090402""(oncogene-induced cell senescence)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0098508""(endothelial to hematopoietic transition)|go:""GO:0120186""(negative regulation of protein localization to chromatin)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900745""(positive regulation of p38MAPK cascade)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904151""(positive regulation of microglial cell mediated cytotoxicity)|go:""GO:1904178""(negative regulation of adipose tissue development)|go:""GO:1904238""(pericyte cell differentiation)|go:""GO:1905036""(positive regulation of antifungal innate immune response)|go:""GO:1905453""(regulation of myeloid progenitor cell differentiation)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR046328|mint:P17947|rcsb pdb:8E3K|rcsb pdb:8E3R|rcsb pdb:8E4H|rcsb pdb:8E5Y|rcsb pdb:8EBH|rcsb pdb:8EE9|rcsb pdb:8EJ6|rcsb pdb:8EJ8|rcsb pdb:8EK3|rcsb pdb:8EK8|rcsb pdb:8EKJ|rcsb pdb:8EKU|rcsb pdb:8EKV|rcsb pdb:8EKZ|rcsb pdb:8EM9|rcsb pdb:8EMD|rcsb pdb:8ENG|rcsb pdb:8EO1|rcsb pdb:8EO4|rcsb pdb:8EQG|rcsb pdb:8EQK|rcsb pdb:8EQL|rcsb pdb:8T9U|rcsb pdb:8UFF|rcsb pdb:8UFK|rcsb pdb:8UFZ|rcsb pdb:8UHK|rcsb pdb:8V9N|rcsb pdb:8VDH|rcsb pdb:8VDI|reactome:R-HSA-8939236|reactome:R-HSA-9616222|refseq:NP_001074016.1|refseq:NP_003111.2|efo:""Orphanet:33110""|dip:DIP-953N|panther:PTHR11849(orthology-group)"	"interpro:IPR029056|interpro:IPR011611(Carbohydrate/purine kinase)|refseq:YP_169808.1|refseq:WP_003020716.1|go:""GO:0006796""(phosphate-containing compound metabolic process)|go:""GO:0016301""(kinase activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HmODprNJYXNKmGXiSJQt5/xTLY09606	rogid:b1Rco2AfcpxnysDJ3UE2gll3Jl8177416	intact-crc:90124FC087D819C6|rigid:fFly1CfrxMI0fpFtV4eG9+uDZYY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5ZTL3	intact:EBI-4399559	intact:EBI-40230387	dip:DIP-24261N	psi-mi:q5ztl3_legph(display_long)|uniprotkb:lpg2148(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Zhu et al. (2018)	imex:IM-29682|pubmed:30107915	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40230385|imex:IM-29682-1	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_010947859.1|rcsb pdb:5SUJ|rcsb pdb:5YM9|rcsb pdb:6JKY|rcsb pdb:6K11|rcsb pdb:6LP2|rcsb pdb:6LW4|rcsb pdb:7BXF|mint:Q5ZTL3|refseq:YP_096161.1|interpro:IPR054021	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	-	-	no-uniprot-update:	"figure legend:fig. 1a-c; fig. 2b; suppl fig.1; suppl table2|comment:""\""More or less the same affinity trend  was observed for C-terminus truncated ubiquitin ((1e75), (1e74),  (1e73), (1e72) and (1e71)) with Lpg2148 (Cys83Ala), while no af-  finity was observed for ubiquitin (1e70) as illustrated in (Fig. 1B, C,  Fig. S1).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6295.0x10^-7 ~7.35(molar)	2023/01/26	2024/11/14	rogid:2nka7tT514Z+hFWUs4t7fTKSPvc272624	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	intact-crc:D2D1E82301735602|rigid:eENRWmsDloGMx2LuJoE1IzQLPSQ	false	mutation with no effect:83-83|mutation disrupting interaction:83-83,33-33	necessary binding region:70-75|his tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5ZTL3	intact:EBI-4399559	intact:EBI-40230387	dip:DIP-24261N	psi-mi:q5ztl3_legph(display_long)|uniprotkb:lpg2148(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	"psi-mi:""MI:2281""(deamidation assay)"	Zhu et al. (2018)	imex:IM-29682|pubmed:30107915	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2280""(deamidation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40243408|imex:IM-29682-3	intact-miscore:0.56	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_010947859.1|rcsb pdb:5SUJ|rcsb pdb:5YM9|rcsb pdb:6JKY|rcsb pdb:6K11|rcsb pdb:6LP2|rcsb pdb:6LW4|rcsb pdb:7BXF|mint:Q5ZTL3|refseq:YP_096161.1|interpro:IPR054021	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	-	-	no-uniprot-update:	"figure legend:fig. 1d suppl.fig.2|comment:""\""To support the vital role of C-terminus of ubiquitin in interaction with Lpg2148, we also performed enzyme titration experiments. Based on the results of enzyme titration assay, deamidase acivity still exists even though C-terminus of Ubiquitin is truncated at 68th as illustrated in (Fig. 1D and S2).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6295.0x10^-7 ~7.35(molar)	2023/01/26	2024/11/14	rogid:2nka7tT514Z+hFWUs4t7fTKSPvc272624	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	intact-crc:EE3D7015DEE08E2E|rigid:eENRWmsDloGMx2LuJoE1IzQLPSQ	false	mutation with no effect:83-83	his tag:n-n	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q5ZU30	uniprotkb:P62820	intact:EBI-40253342	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:seta_legph(display_long)|uniprotkb:Effector protein SetA(gene name synonym)|uniprotkb:Subversion of eukaryotic vesicle trafficking A(gene name synonym)|uniprotkb:lpg1978(locus name)|uniprotkb:setA(gene name)|psi-mi:setA(display_short)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40253340|imex:IM-29713-1	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000030""(mannosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0051999""(mannosyl-inositol phosphorylceramide biosynthetic process)|rcsb pdb:7TOD|refseq:WP_010947694.1|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|refseq:YP_095994.1|mint:Q5ZU30|interpro:IPR051706"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:fig. 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/01/31	2025/03/10	rogid:pbvFD7m2FXE+nbm9ZDMBPguujik272624	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:5387D5D2780B79F3|rigid:S2JUtxgfdwcu/7FbofaaXRp1xPk	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q5ZU30	uniprotkb:P51148	intact:EBI-40253342	intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689.5|ensembl:ENSP00000377440.3|intact:EBI-21355794	psi-mi:seta_legph(display_long)|uniprotkb:Effector protein SetA(gene name synonym)|uniprotkb:Subversion of eukaryotic vesicle trafficking A(gene name synonym)|uniprotkb:lpg1978(locus name)|uniprotkb:setA(gene name)|psi-mi:setA(display_short)	psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40253340|imex:IM-29713-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000030""(mannosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0051999""(mannosyl-inositol phosphorylceramide biosynthetic process)|rcsb pdb:7TOD|refseq:WP_010947694.1|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|refseq:YP_095994.1|mint:Q5ZU30|interpro:IPR051706"	"refseq:NP_004574.2|refseq:NP_958842.1|refseq:NP_001238968.1|ensembl:ENSG00000108774.15(gene)|ensembl:ENST00000346213.9(transcript)|ensembl:ENST00000393860.7(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0012505""(endomembrane system)|go:""GO:0019003""(GDP binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042470""(melanosome)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51148|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9820960|refseq:XP_011523392.1|refseq:XP_011523393.1|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:fig. 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/01/31	2025/03/10	rogid:pbvFD7m2FXE+nbm9ZDMBPguujik272624	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	intact-crc:5387D5D2780B79F3|rigid:S2JUtxgfdwcu/7FbofaaXRp1xPk	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q5ZU30	uniprotkb:P51149	intact:EBI-40253342	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062.3|ensembl:ENSP00000501618.1|ensembl:ENSP00000502000.1|ensembl:ENSP00000502088.1|ensembl:ENSP00000502486.1	psi-mi:seta_legph(display_long)|uniprotkb:Effector protein SetA(gene name synonym)|uniprotkb:Subversion of eukaryotic vesicle trafficking A(gene name synonym)|uniprotkb:lpg1978(locus name)|uniprotkb:setA(gene name)|psi-mi:setA(display_short)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40253340|imex:IM-29713-1	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000030""(mannosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0051999""(mannosyl-inositol phosphorylceramide biosynthetic process)|rcsb pdb:7TOD|refseq:WP_010947694.1|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|refseq:YP_095994.1|mint:Q5ZU30|interpro:IPR051706"	"ensembl:ENSG00000075785.14(gene)|ensembl:ENST00000265062.8(transcript)|ensembl:ENST00000674589.1(transcript)|ensembl:ENST00000675342.1(transcript)|ensembl:ENST00000675497.1(transcript)|ensembl:ENST00000676214.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0019003""(GDP binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0036466""(synaptic vesicle recycling via endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045453""(bone resorption)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048524""(positive regulation of viral process)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090383""(phagosome acidification)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0097208""(alveolar lamellar body)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:1903542""(negative regulation of exosomal secretion)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1905366""(negative regulation of intralumenal vesicle formation)|go:""GO:1905394""(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:3LAW|rcsb pdb:6IYB|rcsb pdb:6WCW|rcsb pdb:7F6J|rcsb pdb:8KB8|rcsb pdb:8ZQ3|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|refseq:NP_004628.4|efo:""Orphanet:99936""|dip:DIP-39879N|panther:PTHR47981(orthology-group)"	-	-	-	figure legend:fig. 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/01/31	2025/03/10	rogid:pbvFD7m2FXE+nbm9ZDMBPguujik272624	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	intact-crc:5387D5D2780B79F3|rigid:S2JUtxgfdwcu/7FbofaaXRp1xPk	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q8ZQC8	uniprotkb:P51149	intact:EBI-40253356	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062.3|ensembl:ENSP00000501618.1|ensembl:ENSP00000502000.1|ensembl:ENSP00000502088.1|ensembl:ENSP00000502486.1	psi-mi:sopd2_salty(display_long)|uniprotkb:Salmonella outer protein D 2(gene name synonym)|uniprotkb:STM0972(locus name)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40253354|imex:IM-29713-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0033644""(host cell membrane)|rcsb pdb:5CQ9|refseq:WP_001145561.1|interpro:IPR022747|refseq:NP_459947.1|mint:Q8ZQC8"	"ensembl:ENSG00000075785.14(gene)|ensembl:ENST00000265062.8(transcript)|ensembl:ENST00000674589.1(transcript)|ensembl:ENST00000675342.1(transcript)|ensembl:ENST00000675497.1(transcript)|ensembl:ENST00000676214.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0019003""(GDP binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0036466""(synaptic vesicle recycling via endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045453""(bone resorption)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048524""(positive regulation of viral process)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090383""(phagosome acidification)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0097208""(alveolar lamellar body)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:1903542""(negative regulation of exosomal secretion)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1905366""(negative regulation of intralumenal vesicle formation)|go:""GO:1905394""(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:3LAW|rcsb pdb:6IYB|rcsb pdb:6WCW|rcsb pdb:7F6J|rcsb pdb:8KB8|rcsb pdb:8ZQ3|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|refseq:NP_004628.4|efo:""Orphanet:99936""|dip:DIP-39879N|panther:PTHR47981(orthology-group)"	-	-	-	figure legend:fig.1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/01/31	2025/03/10	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA99287	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	intact-crc:5EE6794A94D7E03A|rigid:AyY9LAyjKXEfXIAeTyPoTeqfBnw	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q8ZQC8	uniprotkb:P61026	intact:EBI-40253356	intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710.4	psi-mi:sopd2_salty(display_long)|uniprotkb:Salmonella outer protein D 2(gene name synonym)|uniprotkb:STM0972(locus name)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)	psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40253354|imex:IM-29713-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0033644""(host cell membrane)|rcsb pdb:5CQ9|refseq:WP_001145561.1|interpro:IPR022747|refseq:NP_459947.1|mint:Q8ZQC8"	"refseq:NP_057215.3|ensembl:ENSG00000084733.11(gene)|ensembl:ENST00000264710.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0007409""(axonogenesis)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0019003""(GDP binding)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0031489""(myosin V binding)|go:""GO:0032593""(insulin-responsive compartment)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045200""(establishment of neuroblast polarity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070382""(exocytic vesicle)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0097051""(establishment of protein localization to endoplasmic reticulum membrane)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0099503""(secretory vesicle)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:P61026|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:fig.1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/01/31	2025/03/10	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA99287	rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606	intact-crc:5EE6794A94D7E03A|rigid:AyY9LAyjKXEfXIAeTyPoTeqfBnw	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q8ZQC8	uniprotkb:P61006	intact:EBI-40253356	intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935.2|intact:EBI-21356948	psi-mi:sopd2_salty(display_long)|uniprotkb:Salmonella outer protein D 2(gene name synonym)|uniprotkb:STM0972(locus name)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)	psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40253354|imex:IM-29713-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0033644""(host cell membrane)|rcsb pdb:5CQ9|refseq:WP_001145561.1|interpro:IPR022747|refseq:NP_459947.1|mint:Q8ZQC8"	"refseq:NP_005361.2|ensembl:ENSG00000167461.12(gene)|rcsb pdb:6YX5|ensembl:ENST00000300935.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0007409""(axonogenesis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0010008""(endosome membrane)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0019003""(GDP binding)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030496""(midbody)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031489""(myosin V binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0048210""(Golgi vesicle fusion to target membrane)|go:""GO:0051223""(regulation of protein transport)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060170""(ciliary membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0097546""(ciliary base)|go:""GO:0097730""(non-motile cilium)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098969""(neurotransmitter receptor transport to postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099003""(vesicle-mediated transport in synapse)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-43703N|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:fig.1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/01/31	2025/03/10	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA99287	rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606	intact-crc:5EE6794A94D7E03A|rigid:AyY9LAyjKXEfXIAeTyPoTeqfBnw	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q5ZU30	uniprotkb:P62820	intact:EBI-40253342	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:seta_legph(display_long)|uniprotkb:Effector protein SetA(gene name synonym)|uniprotkb:Subversion of eukaryotic vesicle trafficking A(gene name synonym)|uniprotkb:lpg1978(locus name)|uniprotkb:setA(gene name)|psi-mi:setA(display_short)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0559""(glycosylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40253439|imex:IM-29713-7	intact-miscore:0.52	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000030""(mannosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0051999""(mannosyl-inositol phosphorylceramide biosynthetic process)|rcsb pdb:7TOD|refseq:WP_010947694.1|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|refseq:YP_095994.1|mint:Q5ZU30|interpro:IPR051706"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	"figure legend:fig. 3b-c;fig. 4b; suppl fig 4, fig. 5a-b|comment:""\""Furthermore, we evaluated the in vitro modification ratios  by loading purified Rab1 with either GDP or a nonhydrolyzable GTP analog GTPγS. Upon incubation with  SetA, LC-MS analyses revealed a higher modification ratio  (2–3 fold) of Rab1:GDP than that of Rab1:GTP (Fig. 4b).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/01/31	2024/11/14	rogid:pbvFD7m2FXE+nbm9ZDMBPguujik272624	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:E99843B95D382000|rigid:XviVmtFmJCbTkLWqqUAStNfuFEA	false	mutation disrupting interaction:134-134,136-136|his tag:?-?	glutathione s tranferase tag:?-?|glycosylated residue:75-75	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q29ST3	uniprotkb:P62820	intact:EBI-15838677	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:drra_legpn(display_long)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:sidM(gene name synonym)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:446(legpn)|taxid:446(Legionella pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:1148""(ampylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40255327|imex:IM-29713-9	intact-miscore:0.54	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0018117""(protein adenylylation)|go:""GO:0018260""(protein guanylylation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044162""(host cell cytoplasmic vesicle membrane)|go:""GO:0044600""(protein guanylyltransferase activity)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070733""(AMPylase activity)|interpro:IPR028057|interpro:IPR033784|interpro:IPR038346|interpro:IPR048717|interpro:IPR048718|rcsb pdb:3NKU|rcsb pdb:5O74|rcsb pdb:6YX5|refseq:WP_010948166.1|dip:DIP-58604N|mint:Q29ST3"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	"figure legend:fig. 5a|comment:""\""Of note is that despite the proximity of the major glucosylation site on Rab1 to residues attacked by L. pneumophila effectors SidM and AnkX, modification of Thr75  by SetA does not detectably interfere with subsequent  AMPylation of Tyr80 or phosphorylcholinationof Ser79  (Fig. 5a, b).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/01/31	2024/11/14	rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE446	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:63FF923C7BD73A7D|rigid:8Vz+PnWsGC82SRdNSOQPosZ0qzE	false	his tag:?-?	glutathione s tranferase tag:?-?|modified L-tyrosine residue:75-75	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q5ZXN6	uniprotkb:P62820	intact:EBI-26359852	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0414""(enzymatic reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40255341|imex:IM-29713-11	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	"figure legend:fig. 5b|comment:""\""Of note is that despite the proximity of the major glucosylation site on Rab1 to residues attacked by L. pneumophila effectors SidM and AnkX, modification of Thr75  by SetA does not detectably interfere with subsequent  AMPylation of Tyr80 or phosphorylcholinationof Ser79  (Fig. 5a, b).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/01/31	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:C75DDE5D5065E8E3|rigid:teaRwcszmazMZ8cwuvrgOk+yiEs	false	his tag:?-?	glutathione s tranferase tag:?-?|modified L-tyrosine residue:79-79	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q5ZU30	uniprotkb:P51149	intact:EBI-40253342	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062.3|ensembl:ENSP00000501618.1|ensembl:ENSP00000502000.1|ensembl:ENSP00000502088.1|ensembl:ENSP00000502486.1	psi-mi:seta_legph(display_long)|uniprotkb:Effector protein SetA(gene name synonym)|uniprotkb:Subversion of eukaryotic vesicle trafficking A(gene name synonym)|uniprotkb:lpg1978(locus name)|uniprotkb:setA(gene name)|psi-mi:setA(display_short)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0559""(glycosylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40255392|imex:IM-29713-17	intact-miscore:0.52	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000030""(mannosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0051999""(mannosyl-inositol phosphorylceramide biosynthetic process)|rcsb pdb:7TOD|refseq:WP_010947694.1|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|refseq:YP_095994.1|mint:Q5ZU30|interpro:IPR051706"	"ensembl:ENSG00000075785.14(gene)|ensembl:ENST00000265062.8(transcript)|ensembl:ENST00000674589.1(transcript)|ensembl:ENST00000675342.1(transcript)|ensembl:ENST00000675497.1(transcript)|ensembl:ENST00000676214.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0019003""(GDP binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0036466""(synaptic vesicle recycling via endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045453""(bone resorption)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048524""(positive regulation of viral process)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090383""(phagosome acidification)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0097208""(alveolar lamellar body)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:1903542""(negative regulation of exosomal secretion)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1905366""(negative regulation of intralumenal vesicle formation)|go:""GO:1905394""(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:3LAW|rcsb pdb:6IYB|rcsb pdb:6WCW|rcsb pdb:7F6J|rcsb pdb:8KB8|rcsb pdb:8ZQ3|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|refseq:NP_004628.4|efo:""Orphanet:99936""|dip:DIP-39879N|panther:PTHR47981(orthology-group)"	-	-	-	"figure legend:suppl fig 5a|comment:""\""Furthermore, we evaluated the in vitro modification ratios  by loading purified Rab1 with either GDP or a nonhydrolyzable GTP analog GTPγS. Upon incubation with  SetA, LC-MS analyses revealed a higher modification ratio  (2–3 fold) of Rab1:GDP than that of Rab1:GTP (Fig. 4b).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/01/31	2025/03/10	rogid:pbvFD7m2FXE+nbm9ZDMBPguujik272624	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	intact-crc:D1B759DD3A4B592E|rigid:7qjzEVz3JaaA5ZAfk9A4dw3MsPY	false	mutation disrupting interaction:134-134,136-136|his tag:?-?	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P62820	uniprotkb:Q29ST3	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	intact:EBI-15838677	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	psi-mi:drra_legpn(display_long)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:sidM(gene name synonym)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:446(legpn)|taxid:446(Legionella pneumophila)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40255413|imex:IM-29713-19	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	"go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0018117""(protein adenylylation)|go:""GO:0018260""(protein guanylylation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044162""(host cell cytoplasmic vesicle membrane)|go:""GO:0044600""(protein guanylyltransferase activity)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070733""(AMPylase activity)|interpro:IPR028057|interpro:IPR033784|interpro:IPR038346|interpro:IPR048717|interpro:IPR048718|rcsb pdb:3NKU|rcsb pdb:5O74|rcsb pdb:6YX5|refseq:WP_010948166.1|dip:DIP-58604N|mint:Q29ST3"	-	-	-	figure legend:suppl. fig. 9|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/01/31	2024/11/14	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE446	intact-crc:65AF7EED413241BB|rigid:8Vz+PnWsGC82SRdNSOQPosZ0qzE	false	ha tag:?-?	his tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q5ZU30	uniprotkb:P62820	intact:EBI-40253342	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:seta_legph(display_long)|uniprotkb:Effector protein SetA(gene name synonym)|uniprotkb:Subversion of eukaryotic vesicle trafficking A(gene name synonym)|uniprotkb:lpg1978(locus name)|uniprotkb:setA(gene name)|psi-mi:setA(display_short)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Wang et al. (2017)	pubmed:30323948|imex:IM-29713	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0559""(glycosylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40255428|imex:IM-29713-23	intact-miscore:0.52	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000030""(mannosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0051999""(mannosyl-inositol phosphorylceramide biosynthetic process)|rcsb pdb:7TOD|refseq:WP_010947694.1|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|refseq:YP_095994.1|mint:Q5ZU30|interpro:IPR051706"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	"figure legend:suppl fig 10|comment:""\""Furthermore, we evaluated the in vitro modification ratios  by loading purified Rab1 with either GDP or a nonhydrolyzable GTP analog GTPγS. Upon incubation with  SetA, LC-MS analyses revealed a higher modification ratio  (2–3 fold) of Rab1:GDP than that of Rab1:GTP (Fig. 4b).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2023/01/31	2024/11/14	rogid:pbvFD7m2FXE+nbm9ZDMBPguujik272624	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:CD645D36266BB3B1|rigid:XviVmtFmJCbTkLWqqUAStNfuFEA	false	his tag:?-?|mutation disrupting interaction:134-134,136-136	glutathione s tranferase tag:?-?|glycosylated residue:75-75	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A3B6UEL2	uniprotkb:P01116	intact:EBI-40255461	intact:EBI-367415|uniprotkb:P01118|uniprotkb:Q96D10|uniprotkb:B0LPF9|uniprotkb:A8K8Z5|ensembl:ENSP00000256078.5	psi-mi:a0a3b6uel2_vibvl(display_long)|uniprotkb:XM78_c20952(orf name)	psi-mi:rask_human(display_long)|uniprotkb:KRAS(gene name)|psi-mi:KRAS(display_short)|uniprotkb:RASK2(gene name synonym)|uniprotkb:KRAS2(gene name synonym)|uniprotkb:K-Ras 2(gene name synonym)|uniprotkb:Ki-Ras(gene name synonym)|uniprotkb:c-K-ras(gene name synonym)|uniprotkb:c-Ki-ras(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Biancucci et al. (2018)	pubmed:30279169|imex:IM-29710	taxid:672(vibvl)|taxid:672(Vibrio vulnificus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40255481|imex:IM-29710-3	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:5W6L|interpro:IPR048461|mint:A0A3B6UEL2	"efo:""Orphanet:1333""|efo:""Orphanet:1340""|efo:""Orphanet:144""|efo:""Orphanet:146""|efo:""Orphanet:2396""|efo:""Orphanet:251615""|efo:""Orphanet:2612""|efo:""Orphanet:268114""|efo:""Orphanet:3339""|efo:""Orphanet:648""|efo:""Orphanet:86834""|ensembl:ENSG00000133703.14(gene)|ensembl:ENST00000256078.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0008542""(visual learning)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010467""(gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019003""(GDP binding)|go:""GO:0021897""(forebrain astrocyte development)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030857""(negative regulation of epithelial cell differentiation)|go:""GO:0032228""(regulation of synaptic transmission, GABAergic)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060441""(epithelial tube branching involved in lung morphogenesis)|go:""GO:0060509""(type I pneumocyte differentiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01116|rcsb pdb:1D8D|rcsb pdb:1D8E|rcsb pdb:1KZO|rcsb pdb:1KZP|rcsb pdb:1N4P|rcsb pdb:1N4Q|rcsb pdb:1N4R|rcsb pdb:1N4S|rcsb pdb:2MSC|rcsb pdb:2MSD|rcsb pdb:2MSE|rcsb pdb:3GFT|rcsb pdb:4DSN|rcsb pdb:4DSO|rcsb pdb:4EPR|rcsb pdb:4EPT|rcsb pdb:4EPV|rcsb pdb:4EPW|rcsb pdb:4EPX|rcsb pdb:4EPY|rcsb pdb:4L8G|rcsb pdb:4LDJ|rcsb pdb:4LPK|rcsb pdb:4LRW|rcsb pdb:4LUC|rcsb pdb:4LV6|rcsb pdb:4LYF|rcsb pdb:4LYH|rcsb pdb:4LYJ|rcsb pdb:4M1O|rcsb pdb:4M1S|rcsb pdb:4M1T|rcsb pdb:4M1W|rcsb pdb:4M1Y|rcsb pdb:4M21|rcsb pdb:4M22|rcsb pdb:4NMM|rcsb pdb:4OBE|rcsb pdb:4PZY|rcsb pdb:4PZZ|rcsb pdb:4Q01|rcsb pdb:4Q02|rcsb pdb:4Q03|rcsb pdb:4QL3|rcsb pdb:4TQ9|rcsb pdb:4TQA|rcsb pdb:4WA7|rcsb pdb:5F2E|rcsb pdb:5KYK|rcsb pdb:5MLA|rcsb pdb:5MLB|rcsb pdb:5O2S|rcsb pdb:5O2T|rcsb pdb:5OCG|rcsb pdb:5OCO|rcsb pdb:5OCT|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5UFE|rcsb pdb:5UFQ|rcsb pdb:5UK9|rcsb pdb:5UQW|rcsb pdb:5US4|rcsb pdb:5USJ|rcsb pdb:5V6S|rcsb pdb:5V6V|rcsb pdb:5V71|rcsb pdb:5V9L|rcsb pdb:5V9O|rcsb pdb:5V9U|rcsb pdb:5VBM|rcsb pdb:5VP7|rcsb pdb:5VPI|rcsb pdb:5VPY|rcsb pdb:5VPZ|rcsb pdb:5VQ0|rcsb pdb:5VQ1|rcsb pdb:5VQ2|rcsb pdb:5VQ6|rcsb pdb:5VQ8|rcsb pdb:5W22|rcsb pdb:5WHA|rcsb pdb:5WHB|rcsb pdb:5WHD|rcsb pdb:5WHE|rcsb pdb:5WLB|rcsb pdb:5WPM|rcsb pdb:5XCO|rcsb pdb:5YXZ|rcsb pdb:5YY1|rcsb pdb:6ARK|rcsb pdb:6ASA|rcsb pdb:6ASE|rcsb pdb:6B0V|rcsb pdb:6B0Y|rcsb pdb:6BOF|rcsb pdb:6BP1|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CU6|rcsb pdb:6E6F|rcsb pdb:6E6G|rcsb pdb:6EPL|rcsb pdb:6EPM|rcsb pdb:6EPN|rcsb pdb:6EPO|rcsb pdb:6EPP|rcsb pdb:6F76|rcsb pdb:6FA1|rcsb pdb:6FA2|rcsb pdb:6FA3|rcsb pdb:6FA4|rcsb pdb:6GJ5|rcsb pdb:6GJ6|rcsb pdb:6GJ7|rcsb pdb:6GJ8|rcsb pdb:6GOD|rcsb pdb:6GOE|rcsb pdb:6GOF|rcsb pdb:6GOG|rcsb pdb:6GOM|rcsb pdb:6GQT|rcsb pdb:6GQW|rcsb pdb:6GQX|rcsb pdb:6GQY|rcsb pdb:6H46|rcsb pdb:6H47|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6M9W|rcsb pdb:6MBQ|rcsb pdb:6MBT|rcsb pdb:6MBU|rcsb pdb:6MNX|rcsb pdb:6MQG|rcsb pdb:6MQN|rcsb pdb:6MS9|rcsb pdb:6MTA|rcsb pdb:6N2J|rcsb pdb:6N2K|rcsb pdb:6O36|rcsb pdb:6O46|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6OB2|rcsb pdb:6OB3|rcsb pdb:6OIM|rcsb pdb:6P0Z|rcsb pdb:6P8W|rcsb pdb:6P8X|rcsb pdb:6P8Y|rcsb pdb:6P8Z|rcsb pdb:6PGO|rcsb pdb:6PGP|rcsb pdb:6PQ3|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6QUU|rcsb pdb:6QUV|rcsb pdb:6QUW|rcsb pdb:6QUX|rcsb pdb:6T5B|rcsb pdb:6T5U|rcsb pdb:6T5V|rcsb pdb:6TAM|rcsb pdb:6TAN|rcsb pdb:6USX|rcsb pdb:6USZ|rcsb pdb:6UT0|rcsb pdb:6V5L|rcsb pdb:6V65|rcsb pdb:6V6F|rcsb pdb:6VC8|rcsb pdb:6VJJ|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:6WGN|rcsb pdb:6WS2|rcsb pdb:6WS4|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6YR8|rcsb pdb:6YXW|rcsb pdb:6ZL5|rcsb pdb:6ZLI|rcsb pdb:7A1W|rcsb pdb:7A1X|rcsb pdb:7A1Y|rcsb pdb:7A47|rcsb pdb:7ACA|rcsb pdb:7ACF|rcsb pdb:7ACH|rcsb pdb:7ACQ|rcsb pdb:7C40|rcsb pdb:7C41|rcsb pdb:7EW9|rcsb pdb:7EWA|rcsb pdb:7EWB|rcsb pdb:7EYX|rcsb pdb:7F0W|rcsb pdb:7KFZ|rcsb pdb:7KMR|rcsb pdb:7KYZ|rcsb pdb:7LC1|rcsb pdb:7LC2|rcsb pdb:7LGI|rcsb pdb:7LZ5|rcsb pdb:7MDP|rcsb pdb:7MQU|rcsb pdb:7NY8|rcsb pdb:7O70|rcsb pdb:7OK3|rcsb pdb:7OK4|rcsb pdb:7OO7|rcsb pdb:7Q9U|rcsb pdb:7R0M|rcsb pdb:7R0N|rcsb pdb:7R0Q|rcsb pdb:7ROV|rcsb pdb:7RP2|rcsb pdb:7RP3|rcsb pdb:7RP4|rcsb pdb:7RPZ|rcsb pdb:7RSC|rcsb pdb:7RSE|rcsb pdb:7RT1|rcsb pdb:7RT2|rcsb pdb:7RT3|rcsb pdb:7RT4|rcsb pdb:7RT5|rcsb pdb:7SCW|rcsb pdb:7SCX|rcsb pdb:7STF|rcsb pdb:7T1F|rcsb pdb:7T47|rcsb pdb:7TLE|rcsb pdb:7TLG|rcsb pdb:7TLK|rcsb pdb:7U8H|rcsb pdb:7VVB|rcsb pdb:7W5R|rcsb pdb:7YCC|rcsb pdb:7YCE|rcsb pdb:7YUZ|rcsb pdb:7YV1|rcsb pdb:8AFB|rcsb pdb:8AFC|rcsb pdb:8AFD|rcsb pdb:8AQ5|rcsb pdb:8AQ7|rcsb pdb:8AZR|rcsb pdb:8AZV|rcsb pdb:8AZX|rcsb pdb:8AZY|rcsb pdb:8AZZ|rcsb pdb:8B00|rcsb pdb:8B69|rcsb pdb:8B6I|rcsb pdb:8B78|rcsb pdb:8BE3|rcsb pdb:8BE4|rcsb pdb:8BE5|rcsb pdb:8BLR|rcsb pdb:8CPR|rcsb pdb:8CX5|rcsb pdb:8DGS|rcsb pdb:8DGT|rcsb pdb:8DNI|rcsb pdb:8DNJ|rcsb pdb:8DNK|rcsb pdb:8DVG|rcsb pdb:8EBZ|rcsb pdb:8ECR|rcsb pdb:8EDY|rcsb pdb:8EER|rcsb pdb:8EIE|rcsb pdb:8EPW|rcsb pdb:8EZG|rcsb pdb:8F0M|rcsb pdb:8FMI|rcsb pdb:8FMJ|rcsb pdb:8FMK|rcsb pdb:8G42|rcsb pdb:8G47|rcsb pdb:8G4F|rcsb pdb:8G4H|rcsb pdb:8G9P|rcsb pdb:8G9Q|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8JGD|rcsb pdb:8JHL|rcsb pdb:8JJS|rcsb pdb:8ONV|rcsb pdb:8PI0|rcsb pdb:8QU8|rcsb pdb:8QUG|rcsb pdb:8QVU|rcsb pdb:8QW6|rcsb pdb:8QW7|rcsb pdb:8R7W|rcsb pdb:8R7X|rcsb pdb:8S8C|rcsb pdb:8STM|rcsb pdb:8STN|rcsb pdb:8T4V|rcsb pdb:8T71|rcsb pdb:8T72|rcsb pdb:8T73|rcsb pdb:8T74|rcsb pdb:8T75|rcsb pdb:8TBF|rcsb pdb:8TBH|rcsb pdb:8TBJ|rcsb pdb:8TBK|rcsb pdb:8TBL|rcsb pdb:8TBM|rcsb pdb:8TBN|rcsb pdb:8TVK|rcsb pdb:8TXE|rcsb pdb:8TXG|rcsb pdb:8TXH|rcsb pdb:8TXJ|rcsb pdb:8TXK|rcsb pdb:8TY2|rcsb pdb:8TY8|rcsb pdb:8TY9|rcsb pdb:8UDR|rcsb pdb:8UN3|rcsb pdb:8UN4|rcsb pdb:8UN5|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8X6R|rcsb pdb:9AX6|rcsb pdb:9BFY|rcsb pdb:9BG1|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-4086398|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5658442|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-8951936|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9753510|reactome:R-HSA-9753512|refseq:NP_004976.2|refseq:NP_203524.1|refseq:XP_006719132.1|refseq:XP_011518955.1|dip:DIP-33951N|panther:PTHR24070(orthology-group)|ensembl:ENSP00000256078.5|ensembl:ENST00000311936.8|ensembl:ENSP00000308495.3|ensembl:ENST00000685328.1|ensembl:ENSP00000508921.1|ensembl:ENST00000688940.1|ensembl:ENSP00000509238.1"	-	-	-	"figure legend:fig. 3, 4|comment:""\""Chelator-treated rRRSP did not show inhibition of activity, even at the highest molar ratio of 1:500 (RRSP:chelator) (Fig. 4,A and B). As a positive control, the nonspecific protease thermolysin was inhibited by both EDTA and 1,10-phenanthroline under the same conditions (Fig. 4C).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/01/31	2024/11/14	rogid:zTJyQ5tQD31bB5cN+/nz8k8UQjA672	rogid:ujXYEgifbSf/thk1UOTW7sKWkX89606	intact-crc:02150C8506FD0EEF|rigid:ETyMZ3kmfQVB+970KBSJ0/8DPgQ	false	his tag:?-?|mutation decreasing interaction:229-229|mutation disrupting interaction:257-257|mutation disrupting interaction:258-258|mutation disrupting interaction:357-357|mutation with no effect:227-227|mutation with no effect:328-328	binding-associated region:1-169	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q5ZU83	uniprotkb:Q9H8S9	intact:EBI-42490031	intact:EBI-748229|uniprotkb:Q53S34|uniprotkb:Q9H3T5|uniprotkb:Q9HAI0|uniprotkb:Q9NVE2|ensembl:ENSP00000379364.3	psi-mi:q5zu83_legph(display_long)|uniprotkb:lpg1924(locus name)	psi-mi:mob1a_human(display_long)|uniprotkb:MOB1A(gene name)|psi-mi:MOB1A(display_short)|uniprotkb:C2orf6(gene name synonym)|uniprotkb:MOB4B(gene name synonym)|uniprotkb:MOBK1B(gene name synonym)|uniprotkb:MOBKL1B(gene name synonym)|uniprotkb:Mob1 alpha(gene name synonym)|uniprotkb:Mob1 homolog 1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1B(gene name synonym)	"psi-mi:""MI:0089""(protein array)"	Lee et al. (2018)	pubmed:30212651|imex:IM-29743	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0217""(phosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-42490029|imex:IM-29743-1	intact-miscore:0.56	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_095941.1|go:""GO:0046872""(metal ion binding)|rcsb pdb:6MCP|rcsb pdb:6MCQ|rcsb pdb:7BYK|mint:Q5ZU83|refseq:WP_010947641.1|interpro:IPR011009(Protein kinase-like)"	"refseq:NP_060691.2|ensembl:ENSG00000114978.18(gene)|ensembl:ENST00000396049.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0035329""(hippo signaling)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9H8S9|rcsb pdb:1PI1|rcsb pdb:4J1V|rcsb pdb:4JIZ|rcsb pdb:5BRK|rcsb pdb:5BRM|rcsb pdb:5TWF|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:5XQZ|rcsb pdb:6MCP|rcsb pdb:6MCQ|reactome:R-HSA-2028269|refseq:NP_001304039.1|refseq:NP_001304040.1|refseq:NP_001304041.1|dip:DIP-36594N|panther:PTHR22599(orthology-group)"	-	-	-	figure legend:fig 2a,b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/01/31	2024/11/14	rogid:zuukWTuo2lerk9vpz1iQXQa1/i0272624	rogid:Gup4pRYJH3cfC6+XkgI27yiF7g89606	intact-crc:D0ECE36C3EB5D384|rigid:wlnsznhuQRAh27tv9AQXv3HEJTU	false	his tag:?-?|mutation disrupting interaction:307-307	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H8S9	uniprotkb:Q5ZU83	intact:EBI-748229|uniprotkb:Q53S34|uniprotkb:Q9H3T5|uniprotkb:Q9HAI0|uniprotkb:Q9NVE2|ensembl:ENSP00000379364.3	intact:EBI-42490031	psi-mi:mob1a_human(display_long)|uniprotkb:MOB1A(gene name)|psi-mi:MOB1A(display_short)|uniprotkb:C2orf6(gene name synonym)|uniprotkb:MOB4B(gene name synonym)|uniprotkb:MOBK1B(gene name synonym)|uniprotkb:MOBKL1B(gene name synonym)|uniprotkb:Mob1 alpha(gene name synonym)|uniprotkb:Mob1 homolog 1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1B(gene name synonym)	psi-mi:q5zu83_legph(display_long)|uniprotkb:lpg1924(locus name)	"psi-mi:""MI:0415""(enzymatic study)"	Lee et al. (2018)	pubmed:30212651|imex:IM-29743	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0217""(phosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-42490056|imex:IM-29743-3	intact-miscore:0.56	-	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060691.2|ensembl:ENSG00000114978.18(gene)|ensembl:ENST00000396049.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0035329""(hippo signaling)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9H8S9|rcsb pdb:1PI1|rcsb pdb:4J1V|rcsb pdb:4JIZ|rcsb pdb:5BRK|rcsb pdb:5BRM|rcsb pdb:5TWF|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:5XQZ|rcsb pdb:6MCP|rcsb pdb:6MCQ|reactome:R-HSA-2028269|refseq:NP_001304039.1|refseq:NP_001304040.1|refseq:NP_001304041.1|dip:DIP-36594N|panther:PTHR22599(orthology-group)"	"refseq:YP_095941.1|go:""GO:0046872""(metal ion binding)|rcsb pdb:6MCP|rcsb pdb:6MCQ|rcsb pdb:7BYK|mint:Q5ZU83|refseq:WP_010947641.1|interpro:IPR011009(Protein kinase-like)"	-	-	-	figure legend:fig 2d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/01/31	2024/11/14	rogid:Gup4pRYJH3cfC6+XkgI27yiF7g89606	rogid:zuukWTuo2lerk9vpz1iQXQa1/i0272624	intact-crc:D126EA05D052E6F6|rigid:wlnsznhuQRAh27tv9AQXv3HEJTU	false	glutathione s tranferase tag:?-?	maltose binding protein tag:?-?|mutation disrupting interaction:307-307	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q9H8S9	uniprotkb:Q5ZU83	intact:EBI-748229|uniprotkb:Q53S34|uniprotkb:Q9H3T5|uniprotkb:Q9HAI0|uniprotkb:Q9NVE2|ensembl:ENSP00000379364.3	intact:EBI-42490031	psi-mi:mob1a_human(display_long)|uniprotkb:MOB1A(gene name)|psi-mi:MOB1A(display_short)|uniprotkb:C2orf6(gene name synonym)|uniprotkb:MOB4B(gene name synonym)|uniprotkb:MOBK1B(gene name synonym)|uniprotkb:MOBKL1B(gene name synonym)|uniprotkb:Mob1 alpha(gene name synonym)|uniprotkb:Mob1 homolog 1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1B(gene name synonym)	psi-mi:q5zu83_legph(display_long)|uniprotkb:lpg1924(locus name)	"psi-mi:""MI:0415""(enzymatic study)"	Lee et al. (2018)	pubmed:30212651|imex:IM-29743	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0217""(phosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-42490073|imex:IM-29743-5	intact-miscore:0.56	-	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060691.2|ensembl:ENSG00000114978.18(gene)|ensembl:ENST00000396049.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0035329""(hippo signaling)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9H8S9|rcsb pdb:1PI1|rcsb pdb:4J1V|rcsb pdb:4JIZ|rcsb pdb:5BRK|rcsb pdb:5BRM|rcsb pdb:5TWF|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:5XQZ|rcsb pdb:6MCP|rcsb pdb:6MCQ|reactome:R-HSA-2028269|refseq:NP_001304039.1|refseq:NP_001304040.1|refseq:NP_001304041.1|dip:DIP-36594N|panther:PTHR22599(orthology-group)"	"refseq:YP_095941.1|go:""GO:0046872""(metal ion binding)|rcsb pdb:6MCP|rcsb pdb:6MCQ|rcsb pdb:7BYK|mint:Q5ZU83|refseq:WP_010947641.1|interpro:IPR011009(Protein kinase-like)"	-	-	-	figure legend:fig 2e suppl.fig 2b-d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/01/31	2024/11/14	rogid:Gup4pRYJH3cfC6+XkgI27yiF7g89606	rogid:zuukWTuo2lerk9vpz1iQXQa1/i0272624	intact-crc:01D77014B4E56FA4|rigid:wlnsznhuQRAh27tv9AQXv3HEJTU	false	glutathione s tranferase tag:?-?|O-phospho-L-threonine:12-12|O-phospho-L-threonine:35-35	maltose binding protein tag:?-?|mutation disrupting interaction:307-307	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q5WZW9	uniprotkb:P11142	intact:EBI-40262565	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378.3|ensembl:ENSP00000432083.1|ensembl:ENSP00000437125.1	psi-mi:q5wzw9_legpl(display_long)|uniprotkb:lpl0262(locus name)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)|uniprotkb:Heat shock protein family A member 8(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Moss et al. (2019)	pubmed:30827827|imex:IM-29744	"taxid:297245(""Legionella pneumophila (strain Lens)"")|taxid:297245(""Legionella pneumophila (strain Lens)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0217""(phosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40271708|imex:IM-29744-1	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|rcsb pdb:5CKW|rcsb pdb:5CLR|refseq:WP_011214527.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:Q5WZW9"	"refseq:NP_006588.1|refseq:NP_694881.1|ensembl:ENSG00000109971.14(gene)|ensembl:ENST00000227378.7(transcript)|ensembl:ENST00000532636.5(transcript)|ensembl:ENST00000534624.6(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000974""(Prp19 complex)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042470""(melanosome)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055131""(C3HC4-type RING finger domain binding)|go:""GO:0061024""(membrane organization)|go:""GO:0061202""(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0061684""(chaperone-mediated autophagy)|go:""GO:0061740""(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0072318""(clathrin coat disassembly)|go:""GO:0072562""(blood microparticle)|go:""GO:0098575""(lumenal side of lysosomal membrane)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0140545""(ATP-dependent protein disaggregase activity)|go:""GO:0140597""(protein carrier chaperone)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|go:""GO:1902904""(negative regulation of supramolecular fiber organization)|go:""GO:1904589""(regulation of protein import)|go:""GO:1904764""(chaperone-mediated autophagy translocation complex disassembly)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9828642|reactome:R-HSA-9833482|refseq:XP_011541100.1|dip:DIP-32874N|panther:PTHR19375(orthology-group)"	-	-	-	figure legend:fig. 2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/03/09	2024/11/14	rogid:5vDRi66KRe7qzT3y7GiobIz/O84297245	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:30CECA9858C8EDB2|rigid:FLQ4t95/XPuS7Dh9LGydZlOjVRg	false	binding-associated region:59-961	mutation disrupting interaction:495-495|mutation decreasing interaction:495-495	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q5WZW9	uniprotkb:P11142	intact:EBI-40262565	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378.3|ensembl:ENSP00000432083.1|ensembl:ENSP00000437125.1	psi-mi:q5wzw9_legpl(display_long)|uniprotkb:lpl0262(locus name)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)|uniprotkb:Heat shock protein family A member 8(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Moss et al. (2019)	pubmed:30827827|imex:IM-29744	"taxid:297245(""Legionella pneumophila (strain Lens)"")|taxid:297245(""Legionella pneumophila (strain Lens)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0217""(phosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-40271743|imex:IM-29744-3	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|rcsb pdb:5CKW|rcsb pdb:5CLR|refseq:WP_011214527.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:Q5WZW9"	"refseq:NP_006588.1|refseq:NP_694881.1|ensembl:ENSG00000109971.14(gene)|ensembl:ENST00000227378.7(transcript)|ensembl:ENST00000532636.5(transcript)|ensembl:ENST00000534624.6(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000974""(Prp19 complex)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042470""(melanosome)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055131""(C3HC4-type RING finger domain binding)|go:""GO:0061024""(membrane organization)|go:""GO:0061202""(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0061684""(chaperone-mediated autophagy)|go:""GO:0061740""(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0072318""(clathrin coat disassembly)|go:""GO:0072562""(blood microparticle)|go:""GO:0098575""(lumenal side of lysosomal membrane)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0140545""(ATP-dependent protein disaggregase activity)|go:""GO:0140597""(protein carrier chaperone)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|go:""GO:1902904""(negative regulation of supramolecular fiber organization)|go:""GO:1904589""(regulation of protein import)|go:""GO:1904764""(chaperone-mediated autophagy translocation complex disassembly)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9828642|reactome:R-HSA-9833482|refseq:XP_011541100.1|dip:DIP-32874N|panther:PTHR19375(orthology-group)"	-	-	-	figure legend:fig. 2c suppl fig 2a-b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/03/09	2024/11/14	rogid:5vDRi66KRe7qzT3y7GiobIz/O84297245	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:9B934B6F9017BFC2|rigid:FLQ4t95/XPuS7Dh9LGydZlOjVRg	false	binding-associated region:59-961	O-phospho-L-threonine:495-495	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q5WZW9	uniprotkb:P54652	intact:EBI-40262565	intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207.6|ensembl:ENSP00000378199.1	psi-mi:q5wzw9_legpl(display_long)|uniprotkb:lpl0262(locus name)	psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short)|uniprotkb:Heat shock protein family A member 2(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Moss et al. (2019)	pubmed:30827827|imex:IM-29744	"taxid:297245(""Legionella pneumophila (strain Lens)"")|taxid:297245(""Legionella pneumophila (strain Lens)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0217""(phosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-42469228|imex:IM-29744-5	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|rcsb pdb:5CKW|rcsb pdb:5CLR|refseq:WP_011214527.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:Q5WZW9"	"refseq:NP_068814.2|ensembl:ENSG00000126803.10(gene)|ensembl:ENST00000247207.7(transcript)|ensembl:ENST00000394709.2(transcript)|go:""GO:0000795""(synaptonemal complex)|go:""GO:0001673""(male germ cell nucleus)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007140""(male meiotic nuclear division)|go:""GO:0007141""(male meiosis I)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007286""(spermatid development)|go:""GO:0009408""(response to heat)|go:""GO:0009409""(response to cold)|go:""GO:0009986""(cell surface)|go:""GO:0010971""(positive regulation of G2/M transition of mitotic cell cycle)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0036128""(CatSper complex)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0048156""(tau protein binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051861""(glycolipid binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070194""(synaptonemal complex disassembly)|go:""GO:0072562""(blood microparticle)|go:""GO:0072687""(meiotic spindle)|go:""GO:0090084""(negative regulation of inclusion body assembly)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-9833482|panther:PTHR19375(orthology-group)"	-	-	-	figure legend:fig. 2c suppl fig 2a-b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/03/09	2024/11/14	rogid:5vDRi66KRe7qzT3y7GiobIz/O84297245	rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606	intact-crc:A207BF3F88B60259|rigid:R15iB4ghJ++L/3NYWO8IEpzATwQ	false	binding-associated region:59-961	O-phospho-L-threonine:498-498	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O52623	uniprotkb:P60953	intact:EBI-602254	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:sope_saltm(display_long)|uniprotkb:sopE(gene name)|psi-mi:sopE(display_short)|uniprotkb:Effector protein SopE(gene name synonym)|uniprotkb:Toxin SopE(gene name synonym)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Buchwald et al. (2002)	pubmed:12093730|imex:IM-23017	taxid:90371(saltm)|taxid:90371(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-602253|rcsb pdb:1gzs|imex:IM-23017-1	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000161707.1|interpro:IPR005414(Salmonella type III secretion SopE effector protein)|interpro:IPR016019(Salmonella type III secretion SopE effector protein, GEF domain)|interpro:IPR016018(Salmonella type III secretion SopE effector protein, N-terminal)|rcsb pdb:1GZS|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0030036""(actin cytoskeleton organization)|interpro:IPR035949"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	-	-	-	3d-r-factors:working 22.6%, free 25.5%|3d-resolution:2.30A|complex-properties:|figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/15	2024/11/07	rogid:jMZa07tHdR7SmHb8YlAPYdvMMCM90371	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:1929346F51F378AC|rigid:F/l16qV6QfAtlrTuT1ot415KJHc	false	binding-associated region:79-240	binding-associated region:1-178	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O52623	uniprotkb:P60953	intact:EBI-602254	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:sope_saltm(display_long)|uniprotkb:sopE(gene name)|psi-mi:sopE(display_short)|uniprotkb:Effector protein SopE(gene name synonym)|uniprotkb:Toxin SopE(gene name synonym)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0949""(gdp/gtp exchange assay)"	Buchwald et al. (2002)	pubmed:12093730|imex:IM-23017	taxid:90371(saltm)|taxid:90371(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0414""(enzymatic reaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-602317|imex:IM-23017-2	intact-miscore:0.56	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000161707.1|interpro:IPR005414(Salmonella type III secretion SopE effector protein)|interpro:IPR016019(Salmonella type III secretion SopE effector protein, GEF domain)|interpro:IPR016018(Salmonella type III secretion SopE effector protein, N-terminal)|rcsb pdb:1GZS|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0030036""(actin cytoskeleton organization)|interpro:IPR035949"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	-	-	-	figure legend:Fig. 2E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/15	2024/11/07	rogid:jMZa07tHdR7SmHb8YlAPYdvMMCM90371	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:2E7588079D74E9F2|rigid:F/l16qV6QfAtlrTuT1ot415KJHc	false	binding-associated region:79-240|mutation decreasing interaction:168-168	binding-associated region:1-178	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9RI12	uniprotkb:Q96FW1	intact:EBI-2849107|uniprotkb:O68717	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551.2|ensembl:ENSP00000444357.1	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Juris et al. (2006)	pubmed:16364312|imex:IM-11026|mint:MINT-5218152	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7968642|mint:MINT-73525|imex:IM-11026-3	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)|mint:MINT-1503423(identity)"	"refseq:NP_060140.2|ensembl:ENSG00000167770.13(gene)|ensembl:ENST00000428192.6(transcript)|ensembl:ENST00000538426.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0055105""(ubiquitin-protein transferase inhibitor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:2000780""(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N|panther:PTHR12931(orthology-group)|mint:MINT-1503432(identity)"	-	"comment:""\""Stoichiometry: 1.0\"""""	"comment:""\""Stoichiometry: 1.0\"""""	figure legend:F4B|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2006/01/13	2025/03/31	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	intact-crc:8A1ACD16B06086AB|rigid:fOb2vzKnU9KF1qi+m5AY+9gndE0	false	flag tag:?-?(MINT-1503426)|mutation:269-269(MINT-1503424)	ha tag:?-?(MINT-1503433)	1	1	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96FW1	uniprotkb:Q9RI12	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551.2|ensembl:ENSP00000444357.1	intact:EBI-2849107|uniprotkb:O68717	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	"psi-mi:""MI:0424""(protein kinase assay)"	Juris et al. (2006)	pubmed:16364312|imex:IM-11026|mint:MINT-5218152	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0217""(phosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7968721|mint:MINT-73527|imex:IM-11026-2	intact-miscore:0.60	-	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060140.2|ensembl:ENSG00000167770.13(gene)|ensembl:ENST00000428192.6(transcript)|ensembl:ENST00000538426.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0055105""(ubiquitin-protein transferase inhibitor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:2000780""(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N|panther:PTHR12931(orthology-group)|mint:MINT-1503450(identity)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)|mint:MINT-1503445(identity)"	-	"comment:""\""Stoichiometry: 1.0\"""""	"comment:""\""Stoichiometry: 1.0\"""""	figure legend:F4|comment:Phosphorylation only in presence of actin|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2024/11/14	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	intact-crc:AA765B0D2B4B03B0|rigid:fOb2vzKnU9KF1qi+m5AY+9gndE0	false	-	-	1	1	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9RI12	uniprotkb:Q96FW1	intact:EBI-2849107|uniprotkb:O68717	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551.2|ensembl:ENSP00000444357.1	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Juris et al. (2006)	pubmed:16364312|imex:IM-11026|mint:MINT-5218152	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7968761|mint:MINT-73524|imex:IM-11026-1	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)|mint:MINT-1503462(identity)"	"refseq:NP_060140.2|ensembl:ENSG00000167770.13(gene)|ensembl:ENST00000428192.6(transcript)|ensembl:ENST00000538426.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0055105""(ubiquitin-protein transferase inhibitor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:2000780""(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N|panther:PTHR12931(orthology-group)|mint:MINT-1503469(identity)"	-	"comment:""\""Stoichiometry: 1.0\"""""	"comment:""\""Stoichiometry: 1.0\"""""	figure legend:F2 F3A|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2025/03/31	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	intact-crc:721CB02DF7FBF59F|rigid:fOb2vzKnU9KF1qi+m5AY+9gndE0	false	tag:?-?(MINT-1503463)	-	1	1	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0032""(de novo protein sequencing by mass spectrometry)"
uniprotkb:P09167	uniprotkb:O75326	intact:EBI-8027669|intact:MINT-1958193	intact:EBI-1753538|uniprotkb:Q1XE81|uniprotkb:Q1XE82|uniprotkb:Q1XE83|uniprotkb:Q1XE84|uniprotkb:Q3MIY5|uniprotkb:B4DDP7|uniprotkb:F5H1S0|ensembl:ENSP00000261918.4|ensembl:ENSP00000500448.1	psi-mi:aera_aerhy(display_long)|uniprotkb:aerA(gene name)|psi-mi:aerA(display_short)	psi-mi:sem7a_human(display_long)|uniprotkb:SEMA7A(gene name)|psi-mi:SEMA7A(display_short)|uniprotkb:CD108(gene name synonym)|uniprotkb:SEMAL(gene name synonym)|uniprotkb:Semaphorin-L(gene name synonym)|uniprotkb:Semaphorin-K1(gene name synonym)|uniprotkb:John-Milton-Hargen human blood group Ag(gene name synonym)|uniprotkb:JMH blood group antigen(gene name synonym)|uniprotkb:CDw108(gene name synonym)	"psi-mi:""MI:0049""(filter binding)"	Iacovache et al. (2006)	pubmed:16424900|imex:IM-11001|mint:MINT-5218244	taxid:644(aerhy)|taxid:644(Aeromonas hydrophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8027723|mint:MINT-1958236|imex:IM-11001-2	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P09167|dip:DIP-42724N|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0090729""(toxin activity)|interpro:IPR005138(Aerolysin/Pertussis toxin APT)|interpro:IPR005830(Aerolysin/haemolysin/leukocidin toxin)|interpro:IPR005831(Aerolysin/haemolysin toxin, conserved site)|interpro:IPR016187(C-type lectin fold)|interpro:IPR037015|interpro:IPR055267|rcsb pdb:1PRE|rcsb pdb:1Z52|rcsb pdb:3C0M|rcsb pdb:3C0N|rcsb pdb:3C0O|rcsb pdb:3G4N|rcsb pdb:3G4O|rcsb pdb:5JZH|rcsb pdb:5JZT|rcsb pdb:5JZW|mint:MINT-1958237(identity)"	"refseq:NP_001139501.1|refseq:NP_003603.1|refseq:NP_001139502.1|ensembl:ENSG00000138623.10(gene)|ensembl:ENSG00000288455.1(gene)|ensembl:ENST00000261918.9(transcript)|ensembl:ENST00000671713.1(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001755""(neural crest cell migration)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0021988""(olfactory lobe development)|go:""GO:0030215""(semaphorin receptor binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0038191""(neuropilin binding)|go:""GO:0045499""(chemorepellent activity)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048675""(axon extension)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0098793""(presynapse)|go:""GO:0098982""(GABA-ergic synapse)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|interpro:IPR042824|mint:O75326|rcsb pdb:3NVQ|reactome:R-HSA-416700|panther:PTHR11036(orthology-group)|mint:MINT-1958242(identity)"	-	"comment:mint|function:Aerolysin is a cytolytic toxin exported by the Gram negative Aeromonas bacteria. The mature toxin binds to eukaryotic cells and aggregates to form holes approximatively 3 nm in diameter, leading to destruction of the membrane permeability barrier and osmotic lysis|comment:""\""Stoichiometry: 1.0\"""""	"comment:""\""Stoichiometry: 1.0\"""""	figure legend:F2A|comment:For semaphorin 7A was used the human UP_ID|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/26	2024/11/14	rogid:AyhML6xpBqNlwHtQuBxoqZzqvAk644	rogid:jvLJrmoDZPhZAxms3wWXHescQas9606	intact-crc:4688057A1BCB677E|rigid:Q75HrMnHiFkRNOCM3WDC9zHZtzA	false	-	-	1	1	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P32004	uniprotkb:P09167	intact:EBI-720783|uniprotkb:B2RMU7|uniprotkb:A0AV65|uniprotkb:Q8TA87|uniprotkb:A4ZYW4|uniprotkb:G3XAF4|ensembl:ENSP00000359077.1	intact:EBI-8027669|intact:MINT-1958193	psi-mi:l1cam_human(display_long)|uniprotkb:L1CAM(gene name)|psi-mi:L1CAM(display_short)|uniprotkb:CAML1(gene name synonym)|uniprotkb:MIC5(gene name synonym)	psi-mi:aera_aerhy(display_long)|uniprotkb:aerA(gene name)|psi-mi:aerA(display_short)	"psi-mi:""MI:0049""(filter binding)"	Iacovache et al. (2006)	pubmed:16424900|imex:IM-11001|mint:MINT-5218244	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:644(aerhy)|taxid:644(Aeromonas hydrophila)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8027692|mint:MINT-1958206|imex:IM-11001-1	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1497""|efo:""Orphanet:2182""|efo:""Orphanet:2466""|efo:""Orphanet:306617""|ensembl:ENSG00000198910.14(gene)|ensembl:ENST00000370060.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006935""(chemotaxis)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007399""(nervous system development)|go:""GO:0007411""(axon guidance)|go:""GO:0008046""(axon guidance receptor activity)|go:""GO:0009986""(cell surface)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031175""(neuron projection development)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044295""(axonal growth cone)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0050808""(synapse organization)|go:""GO:0061564""(axon development)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR051170|mint:P32004|rcsb pdb:8AFO|rcsb pdb:8AFP|reactome:R-HSA-210991|reactome:R-HSA-373760|reactome:R-HSA-437239|reactome:R-HSA-445095|reactome:R-HSA-445144|refseq:NP_000416.1|refseq:NP_001137435.1|refseq:NP_001265045.1|refseq:NP_076493.1|panther:PTHR45080(orthology-group)|mint:MINT-1958207(identity)"	"mint:P09167|dip:DIP-42724N|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0090729""(toxin activity)|interpro:IPR005138(Aerolysin/Pertussis toxin APT)|interpro:IPR005830(Aerolysin/haemolysin/leukocidin toxin)|interpro:IPR005831(Aerolysin/haemolysin toxin, conserved site)|interpro:IPR016187(C-type lectin fold)|interpro:IPR037015|interpro:IPR055267|rcsb pdb:1PRE|rcsb pdb:1Z52|rcsb pdb:3C0M|rcsb pdb:3C0N|rcsb pdb:3C0O|rcsb pdb:3G4N|rcsb pdb:3G4O|rcsb pdb:5JZH|rcsb pdb:5JZT|rcsb pdb:5JZW|mint:MINT-1958208(identity)"	-	"comment:""\""Stoichiometry: 1.0\"""""	"comment:mint|function:Aerolysin is a cytolytic toxin exported by the Gram negative Aeromonas bacteria. The mature toxin binds to eukaryotic cells and aggregates to form holes approximatively 3 nm in diameter, leading to destruction of the membrane permeability barrier and osmotic lysis|comment:""\""Stoichiometry: 1.0\"""""	figure legend:F2A|comment:For N-CAm was used the human UP_ID|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/26	2024/11/14	rogid:ytWIAO1KRRtvqhmtH+CZjN/Hrbs9606	rogid:AyhML6xpBqNlwHtQuBxoqZzqvAk644	intact-crc:E65A31AEE0811513|rigid:1K+JAqjkaKz3YBP41GI++e3ABXU	false	-	-	1	1	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P13423	uniprotkb:Q9H6X2-2	intact:EBI-456868|uniprotkb:Q937W2|uniprotkb:Q937W3|uniprotkb:Q9F5R7|uniprotkb:Q9KH69|uniprotkb:Q9RQU2	intact:EBI-905659|ensembl:ENSP00000386494.3	psi-mi:pag_bacan(display_long)|uniprotkb:PA-83(gene name synonym)|uniprotkb:Anthrax toxins translocating protein(gene name synonym)|uniprotkb:pagA(gene name)|psi-mi:pagA(display_short)|uniprotkb:pag(gene name synonym)|uniprotkb:pXO1-110(locus name)|uniprotkb:BXA0164(locus name)|uniprotkb:GBAA_pXO1_0164(locus name)	psi-mi:q9h6x2-2(display_long)|uniprotkb:ANTXR1(gene name)|psi-mi:ANTXR1(display_short)|uniprotkb:ATR(gene name synonym)|uniprotkb:TEM8(gene name synonym)|uniprotkb:Tumor endothelial marker 8(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Bradley et al. (2003)	pubmed:14507921|imex:IM-19859	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-905641|imex:IM-19859-1	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P13423|refseq:NP_052806.1|refseq:WP_000746487.1|refseq:WP_000746486.1|refseq:WP_000746488.1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0044533""(obsolete positive regulation of apoptotic process in another organism)|go:""GO:0046872""(metal ion binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0090729""(toxin activity)|interpro:IPR003896(Bacterial exotoxin B)|interpro:IPR011658(PA14)|interpro:IPR027439|interpro:IPR027441|interpro:IPR035088|interpro:IPR035331|interpro:IPR037149|interpro:IPR037524|interpro:IPR048853|rcsb pdb:1ACC|rcsb pdb:1T6B|rcsb pdb:1TZN|rcsb pdb:1TZO|rcsb pdb:3ETB|rcsb pdb:3INO|rcsb pdb:3J9C|rcsb pdb:3KWV|rcsb pdb:3MHZ|rcsb pdb:3Q8A|rcsb pdb:3Q8B|rcsb pdb:3Q8C|rcsb pdb:3Q8E|rcsb pdb:3Q8F|rcsb pdb:3TEW|rcsb pdb:3TEX|rcsb pdb:3TEY|rcsb pdb:3TEZ|rcsb pdb:4EE2|rcsb pdb:4H2A|rcsb pdb:4NAM|rcsb pdb:5FR3|rcsb pdb:6PSN|rcsb pdb:6UJI|rcsb pdb:6UZB|rcsb pdb:6UZD|rcsb pdb:6UZE|rcsb pdb:6VRA|rcsb pdb:6WJJ|rcsb pdb:6ZXJ|rcsb pdb:6ZXK|rcsb pdb:6ZXL|rcsb pdb:7KXR|rcsb pdb:7O85|reactome:R-HSA-5210891|dip:DIP-29841N"	intact:EBI-905643(antr1_human)|ensembl:ENSG00000169604.21(gene)|ensembl:ENST00000409349.7(transcript)	-	-	-	"stimulant:Binding of PA to ATR-mycHis is supported by Mn2+ or less efficiently by Mg2+, whereas Ca2+ is not able to support toxin-receptor binding.|sample process:Q9H6X2-2 purified|sample process:P13423 purified|comment:""\""The ATR(glu50ala) mutation is predicted to disrupt metal coordination and  mutation of the MIDAS threonine (thr118ala) is predicted to lock the I domain into a closed conformation. Both mutations are shown to strongly affect the binding pr Atr with toxin althought they do not affect the folding of Atr.\""""|full coverage:Only protein-protein interactions|curation depth:imex curation"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/16	2024/11/14	rogid:xLr/ydN4I0qJ46G/8A3JfZqAbyE1392	rogid:Zf4W6+r4NcIRwEQGEnaj5oENeak9606	intact-crc:45AD9608A5E4B1B6|rigid:rJlXbb8vAe8N9vUnlWL8YDiwJNQ	false	binding-associated region:30-764	myc tag:?-?|his tag:?-?|binding-associated region:1-229|mutation decreasing interaction:50-50|mutation decreasing interaction:118-118	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H6X2-2	uniprotkb:P13423	intact:EBI-905659|ensembl:ENSP00000386494.3	intact:EBI-456868|uniprotkb:Q937W2|uniprotkb:Q937W3|uniprotkb:Q9F5R7|uniprotkb:Q9KH69|uniprotkb:Q9RQU2	psi-mi:q9h6x2-2(display_long)|uniprotkb:ANTXR1(gene name)|psi-mi:ANTXR1(display_short)|uniprotkb:ATR(gene name synonym)|uniprotkb:TEM8(gene name synonym)|uniprotkb:Tumor endothelial marker 8(gene name synonym)	psi-mi:pag_bacan(display_long)|uniprotkb:PA-83(gene name synonym)|uniprotkb:Anthrax toxins translocating protein(gene name synonym)|uniprotkb:pagA(gene name)|psi-mi:pagA(display_short)|uniprotkb:pag(gene name synonym)|uniprotkb:pXO1-110(locus name)|uniprotkb:BXA0164(locus name)|uniprotkb:GBAA_pXO1_0164(locus name)	"psi-mi:""MI:0054""(fluorescence-activated cell sorting)"	Bradley et al. (2003)	pubmed:14507921|imex:IM-19859	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-905739|imex:IM-19859-2	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-905643(antr1_human)|ensembl:ENSG00000169604.21(gene)|ensembl:ENST00000409349.7(transcript)	"mint:P13423|refseq:NP_052806.1|refseq:WP_000746487.1|refseq:WP_000746486.1|refseq:WP_000746488.1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0044533""(obsolete positive regulation of apoptotic process in another organism)|go:""GO:0046872""(metal ion binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0090729""(toxin activity)|interpro:IPR003896(Bacterial exotoxin B)|interpro:IPR011658(PA14)|interpro:IPR027439|interpro:IPR027441|interpro:IPR035088|interpro:IPR035331|interpro:IPR037149|interpro:IPR037524|interpro:IPR048853|rcsb pdb:1ACC|rcsb pdb:1T6B|rcsb pdb:1TZN|rcsb pdb:1TZO|rcsb pdb:3ETB|rcsb pdb:3INO|rcsb pdb:3J9C|rcsb pdb:3KWV|rcsb pdb:3MHZ|rcsb pdb:3Q8A|rcsb pdb:3Q8B|rcsb pdb:3Q8C|rcsb pdb:3Q8E|rcsb pdb:3Q8F|rcsb pdb:3TEW|rcsb pdb:3TEX|rcsb pdb:3TEY|rcsb pdb:3TEZ|rcsb pdb:4EE2|rcsb pdb:4H2A|rcsb pdb:4NAM|rcsb pdb:5FR3|rcsb pdb:6PSN|rcsb pdb:6UJI|rcsb pdb:6UZB|rcsb pdb:6UZD|rcsb pdb:6UZE|rcsb pdb:6VRA|rcsb pdb:6WJJ|rcsb pdb:6ZXJ|rcsb pdb:6ZXK|rcsb pdb:6ZXL|rcsb pdb:7KXR|rcsb pdb:7O85|reactome:R-HSA-5210891|dip:DIP-29841N"	"go:""GO:0009986""(cell surface)"	-	-	"sample process:P13423 purified|comment:""\""The ATR(glu50ala) mutants show no complex formation on the facs analysis and confer full resistance to the toxin to the CHO cells. In the other hand the threonine (thr118ala) mutants have a limited interacting ability with the anthrax toxin and only confer a mild resistance during a cell killing assay.\""""|sample process:Q9H6X2-2 living cell|caution:Although not specified in the paper it is likely that PagA construct include only the aminoacid range 30-764.|full coverage:Only protein-protein interactions|curation depth:imex curation"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/16	2024/11/14	rogid:Zf4W6+r4NcIRwEQGEnaj5oENeak9606	rogid:xLr/ydN4I0qJ46G/8A3JfZqAbyE1392	intact-crc:8A94C2D5188C24E2|rigid:rJlXbb8vAe8N9vUnlWL8YDiwJNQ	false	green fluorescent protein tag:?-?|binding-associated region:1-229|mutation decreasing interaction:50-50|mutation decreasing interaction:118-118	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13423	uniprotkb:Q9H6X2-2	intact:EBI-456868|uniprotkb:Q937W2|uniprotkb:Q937W3|uniprotkb:Q9F5R7|uniprotkb:Q9KH69|uniprotkb:Q9RQU2	intact:EBI-905659|ensembl:ENSP00000386494.3	psi-mi:pag_bacan(display_long)|uniprotkb:PA-83(gene name synonym)|uniprotkb:Anthrax toxins translocating protein(gene name synonym)|uniprotkb:pagA(gene name)|psi-mi:pagA(display_short)|uniprotkb:pag(gene name synonym)|uniprotkb:pXO1-110(locus name)|uniprotkb:BXA0164(locus name)|uniprotkb:GBAA_pXO1_0164(locus name)	psi-mi:q9h6x2-2(display_long)|uniprotkb:ANTXR1(gene name)|psi-mi:ANTXR1(display_short)|uniprotkb:ATR(gene name synonym)|uniprotkb:TEM8(gene name synonym)|uniprotkb:Tumor endothelial marker 8(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Bradley et al. (2003)	pubmed:14507921|imex:IM-19859	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-905790|imex:IM-19859-3	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P13423|refseq:NP_052806.1|refseq:WP_000746487.1|refseq:WP_000746486.1|refseq:WP_000746488.1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0044533""(obsolete positive regulation of apoptotic process in another organism)|go:""GO:0046872""(metal ion binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0090729""(toxin activity)|interpro:IPR003896(Bacterial exotoxin B)|interpro:IPR011658(PA14)|interpro:IPR027439|interpro:IPR027441|interpro:IPR035088|interpro:IPR035331|interpro:IPR037149|interpro:IPR037524|interpro:IPR048853|rcsb pdb:1ACC|rcsb pdb:1T6B|rcsb pdb:1TZN|rcsb pdb:1TZO|rcsb pdb:3ETB|rcsb pdb:3INO|rcsb pdb:3J9C|rcsb pdb:3KWV|rcsb pdb:3MHZ|rcsb pdb:3Q8A|rcsb pdb:3Q8B|rcsb pdb:3Q8C|rcsb pdb:3Q8E|rcsb pdb:3Q8F|rcsb pdb:3TEW|rcsb pdb:3TEX|rcsb pdb:3TEY|rcsb pdb:3TEZ|rcsb pdb:4EE2|rcsb pdb:4H2A|rcsb pdb:4NAM|rcsb pdb:5FR3|rcsb pdb:6PSN|rcsb pdb:6UJI|rcsb pdb:6UZB|rcsb pdb:6UZD|rcsb pdb:6UZE|rcsb pdb:6VRA|rcsb pdb:6WJJ|rcsb pdb:6ZXJ|rcsb pdb:6ZXK|rcsb pdb:6ZXL|rcsb pdb:7KXR|rcsb pdb:7O85|reactome:R-HSA-5210891|dip:DIP-29841N"	intact:EBI-905643(antr1_human)|ensembl:ENSG00000169604.21(gene)|ensembl:ENST00000409349.7(transcript)	-	-	-	sample process:P13423 purified|sample process:Q9H6X2-2 purified|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/16	2024/11/14	rogid:xLr/ydN4I0qJ46G/8A3JfZqAbyE1392	rogid:Zf4W6+r4NcIRwEQGEnaj5oENeak9606	intact-crc:9FF8EAEC525F351A|rigid:rJlXbb8vAe8N9vUnlWL8YDiwJNQ	false	binding-associated region:625-764|mutation decreasing interaction:712-712|glutathione s tranferase tag:?-?	myc tag:?-?|binding-associated region:1-229|his tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q5ZTM4	uniprotkb:O15143	intact:EBI-16631153	intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802.2|ensembl:ENSP00000389631.1|ensembl:ENSP00000398110.2|ensembl:ENSP00000398620.2|ensembl:ENSP00000403211.2|ensembl:ENSP00000410238.2|ensembl:ENSP00000494033.1|ensembl:ENSP00000496599.1	psi-mi:q5ztm4_legph(display_long)|uniprotkb:legK2(gene name)|psi-mi:legK2(display_short)|uniprotkb:lpg2137(locus name)	psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Michard et al. (2015)	imex:IM-26171|pubmed:25944859	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-16631165|imex:IM-26171-4	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004683""(calcium/calmodulin-dependent protein kinase activity)|go:""GO:0005524""(ATP binding)|rcsb pdb:7LSV|mint:Q5ZTM4|refseq:WP_010947848.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|refseq:YP_096150.1"	"refseq:NP_005711.1|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N|ensembl:ENSG00000130429.16(gene)|ensembl:ENST00000414376.6(transcript)|ensembl:ENST00000427217.6(transcript)|ensembl:ENST00000431816.6(transcript)|ensembl:ENST00000451682.5(transcript)|ensembl:ENST00000455009.6(transcript)|ensembl:ENST00000458033.6(transcript)|ensembl:ENST00000645391.1(transcript)|ensembl:ENST00000646101.2(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0005925""(focal adhesion)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0032355""(response to estradiol)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0036284""(tubulobulbar complex)|go:""GO:0043627""(response to estrogen)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|panther:PTHR10709(orthology-group)"	-	-	-	figure legend:f1a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/11/27	2025/02/28	rogid:d3U+ijel2dEEbT2t3MQ5eYmj430272624	rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606	intact-crc:4DB69B4918D7492E|rigid:tcbwFFkHTfIEWr0CaD89bDj2riU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5ZTM4	uniprotkb:P61158	intact:EBI-16631153	intact:EBI-351428|uniprotkb:P32391|uniprotkb:Q53QM2|ensembl:ENSP00000263238.2|intact:EBI-21359005	psi-mi:q5ztm4_legph(display_long)|uniprotkb:legK2(gene name)|psi-mi:legK2(display_short)|uniprotkb:lpg2137(locus name)	psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Michard et al. (2015)	imex:IM-26171|pubmed:25944859	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-16825585|imex:IM-26171-8	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004683""(calcium/calmodulin-dependent protein kinase activity)|go:""GO:0005524""(ATP binding)|rcsb pdb:7LSV|mint:Q5ZTM4|refseq:WP_010947848.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|refseq:YP_096150.1"	"refseq:NP_005712.1|ensembl:ENSG00000115091.12(gene)|ensembl:ENST00000263238.7(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0008356""(asymmetric cell division)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016344""(meiotic chromosome movement towards spindle pole)|go:""GO:0030027""(lamellipodium)|go:""GO:0033206""(meiotic cytokinesis)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051653""(spindle localization)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070358""(actin polymerization-dependent cell motility)|go:""GO:0071346""(cellular response to type II interferon)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N|panther:PTHR11937(orthology-group)"	-	-	-	figure legend:f1a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/11/27	2025/02/28	rogid:d3U+ijel2dEEbT2t3MQ5eYmj430272624	rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606	intact-crc:69317FFAF8C1BBB1|rigid:TCYrQ716zYfI+wIkPPgLeG8aVEw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5ZTM4	uniprotkb:O15143	intact:EBI-16631153	intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802.2|ensembl:ENSP00000389631.1|ensembl:ENSP00000398110.2|ensembl:ENSP00000398620.2|ensembl:ENSP00000403211.2|ensembl:ENSP00000410238.2|ensembl:ENSP00000494033.1|ensembl:ENSP00000496599.1	psi-mi:q5ztm4_legph(display_long)|uniprotkb:legK2(gene name)|psi-mi:legK2(display_short)|uniprotkb:lpg2137(locus name)	psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Michard et al. (2015)	imex:IM-26171|pubmed:25944859	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-16631178|imex:IM-26171-3	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004683""(calcium/calmodulin-dependent protein kinase activity)|go:""GO:0005524""(ATP binding)|rcsb pdb:7LSV|mint:Q5ZTM4|refseq:WP_010947848.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|refseq:YP_096150.1"	"refseq:NP_005711.1|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N|ensembl:ENSG00000130429.16(gene)|ensembl:ENST00000414376.6(transcript)|ensembl:ENST00000427217.6(transcript)|ensembl:ENST00000431816.6(transcript)|ensembl:ENST00000451682.5(transcript)|ensembl:ENST00000455009.6(transcript)|ensembl:ENST00000458033.6(transcript)|ensembl:ENST00000645391.1(transcript)|ensembl:ENST00000646101.2(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0005925""(focal adhesion)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0032355""(response to estradiol)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0036284""(tubulobulbar complex)|go:""GO:0043627""(response to estrogen)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|panther:PTHR10709(orthology-group)"	-	-	-	figure legend:f1b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2017/11/27	2025/02/28	rogid:d3U+ijel2dEEbT2t3MQ5eYmj430272624	rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606	intact-crc:AFD796EE81A8D3B2|rigid:tcbwFFkHTfIEWr0CaD89bDj2riU	false	glutathione s tranferase tag:n-n	flag tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q5ZTM4	uniprotkb:P61158	intact:EBI-16631153	intact:EBI-351428|uniprotkb:P32391|uniprotkb:Q53QM2|ensembl:ENSP00000263238.2|intact:EBI-21359005	psi-mi:q5ztm4_legph(display_long)|uniprotkb:legK2(gene name)|psi-mi:legK2(display_short)|uniprotkb:lpg2137(locus name)	psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Michard et al. (2015)	imex:IM-26171|pubmed:25944859	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-16631254|imex:IM-26171-6	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004683""(calcium/calmodulin-dependent protein kinase activity)|go:""GO:0005524""(ATP binding)|rcsb pdb:7LSV|mint:Q5ZTM4|refseq:WP_010947848.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|refseq:YP_096150.1"	"refseq:NP_005712.1|ensembl:ENSG00000115091.12(gene)|ensembl:ENST00000263238.7(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0008356""(asymmetric cell division)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016344""(meiotic chromosome movement towards spindle pole)|go:""GO:0030027""(lamellipodium)|go:""GO:0033206""(meiotic cytokinesis)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051653""(spindle localization)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070358""(actin polymerization-dependent cell motility)|go:""GO:0071346""(cellular response to type II interferon)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N|panther:PTHR11937(orthology-group)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0071944""(cell periphery)"	-	-	figure legend:f1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2017/11/27	2025/02/28	rogid:d3U+ijel2dEEbT2t3MQ5eYmj430272624	rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606	intact-crc:5F4C1C1B2DB609CF|rigid:TCYrQ716zYfI+wIkPPgLeG8aVEw	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q5ZTM4	uniprotkb:O15143	intact:EBI-16631153	intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802.2|ensembl:ENSP00000389631.1|ensembl:ENSP00000398110.2|ensembl:ENSP00000398620.2|ensembl:ENSP00000403211.2|ensembl:ENSP00000410238.2|ensembl:ENSP00000494033.1|ensembl:ENSP00000496599.1	psi-mi:q5ztm4_legph(display_long)|uniprotkb:legK2(gene name)|psi-mi:legK2(display_short)|uniprotkb:lpg2137(locus name)	psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Michard et al. (2015)	imex:IM-26171|pubmed:25944859	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-16825608|imex:IM-26171-10	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004683""(calcium/calmodulin-dependent protein kinase activity)|go:""GO:0005524""(ATP binding)|rcsb pdb:7LSV|mint:Q5ZTM4|refseq:WP_010947848.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|refseq:YP_096150.1"	"refseq:NP_005711.1|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N|ensembl:ENSG00000130429.16(gene)|ensembl:ENST00000414376.6(transcript)|ensembl:ENST00000427217.6(transcript)|ensembl:ENST00000431816.6(transcript)|ensembl:ENST00000451682.5(transcript)|ensembl:ENST00000455009.6(transcript)|ensembl:ENST00000458033.6(transcript)|ensembl:ENST00000645391.1(transcript)|ensembl:ENST00000646101.2(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0005925""(focal adhesion)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0032355""(response to estradiol)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0036284""(tubulobulbar complex)|go:""GO:0043627""(response to estrogen)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|panther:PTHR10709(orthology-group)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0071944""(cell periphery)"	-	-	figure legend:f1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2017/11/27	2025/02/28	rogid:d3U+ijel2dEEbT2t3MQ5eYmj430272624	rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606	intact-crc:1DFE41EDEB9B6392|rigid:tcbwFFkHTfIEWr0CaD89bDj2riU	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P68036-1	uniprotkb:Q99PZ6	intact:EBI-15556257|ensembl:ENSP00000344259.5	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16107237|imex:IM-23108-1|dip:DIP-197139E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	ensembl:ENSG00000185651.16(gene)|ensembl:ENST00000342192.9(transcript)|intact:EBI-711173(isoform-parent)	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	intact-crc:916AABB8869A3410|rigid:D3ifyt2VNfFOazL+qfypeuhGmkc	false	-	sufficient binding region:26-196	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	uniprotkb:P68036-1	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-15556257|ensembl:ENSP00000344259.5	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16107256|imex:IM-23108-2|dip:DIP-197137E	intact-miscore:0.65	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	ensembl:ENSG00000185651.16(gene)|ensembl:ENST00000342192.9(transcript)|intact:EBI-711173(isoform-parent)	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:942744BB0DD5EB99|rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	intact:EBI-4399559	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	dip:DIP-24261N	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16107256|imex:IM-23108-2|dip:DIP-197137E	intact-miscore:0.67	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	"psi-mi:""MI:0465""(dip)"	-	no-uniprot-update:	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	intact-crc:942744BB0DD5EB99|rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	uniprotkb:P68036-1	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-15556257|ensembl:ENSP00000344259.5	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	"psi-mi:""MI:0071""(molecular sieving)"	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16107297|imex:IM-23108-4|dip:DIP-197137E	intact-miscore:0.65	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	ensembl:ENSG00000185651.16(gene)|ensembl:ENST00000342192.9(transcript)|intact:EBI-711173(isoform-parent)	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:6E2CCF5E382A5A61|rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	intact:EBI-4399559	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	dip:DIP-24261N	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	"psi-mi:""MI:0071""(molecular sieving)"	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16107297|imex:IM-23108-4|dip:DIP-197137E	intact-miscore:0.67	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	"psi-mi:""MI:0465""(dip)"	-	no-uniprot-update:	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	intact-crc:6E2CCF5E382A5A61|rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	uniprotkb:P68036-1	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-15556257|ensembl:ENSP00000344259.5	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16107338|imex:IM-23108-6|dip:DIP-197137E	intact-miscore:0.65	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	ensembl:ENSG00000185651.16(gene)|ensembl:ENST00000342192.9(transcript)|intact:EBI-711173(isoform-parent)	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:28E38E5A5C3CFBC3|rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	intact:EBI-4399559	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	dip:DIP-24261N	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	"psi-mi:""MI:0114""(x-ray crystallography)"	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16107338|imex:IM-23108-6|dip:DIP-197137E	intact-miscore:0.67	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	"psi-mi:""MI:0465""(dip)"	-	no-uniprot-update:	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	intact-crc:28E38E5A5C3CFBC3|rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-4399559	uniprotkb:Q99PZ6	dip:DIP-24261N	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:""MI:0077""(nuclear magnetic resonance)"	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16107317|imex:IM-23108-5|dip:DIP-197138E	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"psi-mi:""MI:0465""(dip)"	no-uniprot-update:	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	intact-crc:F26D81A5027F405A|rigid:5jhnWPY9q/plfb350HVBqacJhI8	false	-	sufficient binding region:26-196	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-4399559	uniprotkb:Q99PZ6	dip:DIP-24261N	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16107358|imex:IM-23108-7|dip:DIP-197138E	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"psi-mi:""MI:0465""(dip)"	no-uniprot-update:	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	intact-crc:072E0B4D4F36EF76|rigid:5jhnWPY9q/plfb350HVBqacJhI8	false	-	sufficient binding region:26-196	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yuan et al. (2015)	pubmed:26812398|imex:IM-25958	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740286|imex:IM-25958-3	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:1C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/18	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:26FDD2EDD7D99585|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	glutathione s tranferase tag:?-?	binding-associated region:1-30|biotin tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Yuan et al. (2015)	pubmed:26812398|imex:IM-25958	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740303|imex:IM-25958-5	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-bgc823)|taxid:9606(Homo sapiens BGC823 stomach adenocarcinoma cell)	-	2017/01/18	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:835DD28E0DF4D99D|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P07355	uniprotkb:P15363	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-12740262	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Yuan et al. (2015)	pubmed:26812398|imex:IM-25958	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740314|imex:IM-25958-7	intact-miscore:0.78	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	-	-	-	figure legend:4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-bgc823)|taxid:9606(Homo sapiens BGC823 stomach adenocarcinoma cell)	-	2017/01/18	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	intact-crc:71A56BB7EA4AD887|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	binding-associated region:1-30	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Yuan et al. (2015)	pubmed:26812398|imex:IM-25958	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740327|imex:IM-25958-9	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2017/01/18	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:BB514CE26CFF6605|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P07355	uniprotkb:P15363	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-12740262	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Yuan et al. (2015)	pubmed:26812398|imex:IM-25958	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740331|imex:IM-25958-11	intact-miscore:0.78	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	-	-	-	figure legend:4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2017/01/18	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	intact-crc:3DBC6D477E07DF3C|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	binding-associated region:1-30	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Yuan et al. (2015)	pubmed:26812398|imex:IM-25958	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740345|imex:IM-25958-13	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-bgc823)|taxid:9606(Homo sapiens BGC823 stomach adenocarcinoma cell)	-	2017/01/18	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:2A320D6F63AB1786|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	-	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P07355	uniprotkb:P15363	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-12740262	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Yuan et al. (2015)	pubmed:26812398|imex:IM-25958	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740349|imex:IM-25958-15	intact-miscore:0.78	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	-	-	-	figure legend:4B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-bgc823)|taxid:9606(Homo sapiens BGC823 stomach adenocarcinoma cell)	-	2017/01/18	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	intact-crc:4981859C7EDAC3F6|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	-	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Yuan et al. (2015)	pubmed:26812398|imex:IM-25958	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740363|imex:IM-25958-17	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2017/01/18	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:BDD743CA7E7CE582|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	-	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P07355	uniprotkb:P15363	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-12740262	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Yuan et al. (2015)	pubmed:26812398|imex:IM-25958	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740367|imex:IM-25958-19	intact-miscore:0.78	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	-	-	-	figure legend:4B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2017/01/18	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	intact-crc:ADBC2A4B1C8A6D71|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	-	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P23568	uniprotkb:P02751	intact:EBI-2259072|uniprotkb:P75126	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:eftu_mycpn(display_long)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)|uniprotkb:MP177(orf name)|uniprotkb:MPN_665(locus name)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Balasubramanian et al. (2008)	pubmed:18411296|imex:IM-25904	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13470056|imex:IM-25904-1	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110354.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|go:""GO:0001968""(fibronectin binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016020""(membrane)|interpro:IPR050055|refseq:WP_010875022.1|interpro:IPR033720|interpro:IPR027417|interpro:IPR031157|rcsb pdb:7PAJ|rcsb pdb:7PAK|rcsb pdb:7PHA|rcsb pdb:7PI9|rcsb pdb:7PIP|interpro:IPR041709"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:1C, 2C, 3C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/19	2025/03/25	rogid:+FLTR73UaUM3d3A4f03sRpgS5EA272634	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:7660F4449411A6DC|rigid:lQqCzG2GIZNp+ITqNEhIdPLktyY	false	sufficient binding region:91-215|his tag:n-n|sufficient binding region:215-292|sufficient binding region:314-394	-	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P23568	uniprotkb:P02751	intact:EBI-2259072|uniprotkb:P75126	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:eftu_mycpn(display_long)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)|uniprotkb:MP177(orf name)|uniprotkb:MPN_665(locus name)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Balasubramanian et al. (2008)	pubmed:18411296|imex:IM-25904	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13483306|imex:IM-25904-3	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110354.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|go:""GO:0001968""(fibronectin binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016020""(membrane)|interpro:IPR050055|refseq:WP_010875022.1|interpro:IPR033720|interpro:IPR027417|interpro:IPR031157|rcsb pdb:7PAJ|rcsb pdb:7PAK|rcsb pdb:7PHA|rcsb pdb:7PI9|rcsb pdb:7PIP|interpro:IPR041709"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:4|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/19	2025/03/25	rogid:+FLTR73UaUM3d3A4f03sRpgS5EA272634	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:CA83913618DBCB0F|rigid:lQqCzG2GIZNp+ITqNEhIdPLktyY	false	binding-associated region:192-314|his tag:n-n|binding-associated region:292-394	binding-associated region:1812..1812-2082..2082|binding-associated region:1358..1358-1631..1631|binding-associated region:308..308-608..608|binding-associated region:52..52-272..272	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P75409	uniprotkb:Q8IWL2	intact:EBI-2259548|uniprotkb:Q1PD42|uniprotkb:Q1PD43|uniprotkb:Q1PD44|uniprotkb:Q1PD45|uniprotkb:Q1PD46	intact:EBI-11316418|uniprotkb:Q14DV4|uniprotkb:Q5RIR5|uniprotkb:Q5RIR7|uniprotkb:Q6PIT0|uniprotkb:Q8TC19|uniprotkb:A8K3T8|uniprotkb:B7ZW50|uniprotkb:E3VLD8|uniprotkb:E3VLD9|uniprotkb:E3VLE0|uniprotkb:E3VLE1|uniprotkb:G5E9J3|uniprotkb:P07714|ensembl:ENSP00000381633.3|ensembl:ENSP00000411102.2	psi-mi:cards_mycpn(display_long)|uniprotkb:cards(gene name)|psi-mi:cards(display_short)|uniprotkb:ADP-ribosyltransferase CARDS(gene name synonym)|uniprotkb:Community-Acquired Respiratory Distress Syndrome Toxin(gene name synonym)|uniprotkb:MP464(orf name)|uniprotkb:MPN_372(locus name)	psi-mi:sfta1_human(display_long)|uniprotkb:Alveolar proteinosis protein(gene name synonym)|uniprotkb:Collectin-4(gene name synonym)|uniprotkb:35 kDa pulmonary surfactant-associated protein(gene name synonym)|uniprotkb:SFTPA1(gene name)|psi-mi:SFTPA1(display_short)|uniprotkb:COLEC4(gene name synonym)|uniprotkb:PSAP(gene name synonym)|uniprotkb:SFTP1(gene name synonym)|uniprotkb:SFTPA(gene name synonym)|uniprotkb:SFTPA1B(gene name synonym)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Kannan et al. (2005)	pubmed:15845487|imex:IM-25892	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13483417|imex:IM-25892-1	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003898(Bordetella pertussis toxin A)|refseq:NP_110060.1|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008289""(lipid binding)|go:""GO:0009986""(cell surface)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0033099""(attachment organelle)|go:""GO:0042995""(cell projection)|go:""GO:0044075""(symbiont-mediated perturbation of host vacuole organization)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0090729""(toxin activity)|interpro:IPR055042|interpro:IPR055043|refseq:WP_010874728.1|rcsb pdb:4TLV|rcsb pdb:4TLW"	"ensembl:ENSG00000122852.15(gene)|ensembl:ENST00000398636.8(transcript)|ensembl:ENST00000428376.6(transcript)|go:""GO:0005319""(lipid transporter activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0005771""(multivesicular body)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007585""(respiratory gaseous exchange by respiratory system)|go:""GO:0008228""(opsonization)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0042599""(lamellar body)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033990|interpro:IPR051663|reactome:R-HSA-166016|reactome:R-HSA-168179|reactome:R-HSA-391160|reactome:R-HSA-5683826|reactome:R-HSA-5686938|reactome:R-HSA-5688849|reactome:R-HSA-5688890|refseq:NP_001087239.2|refseq:NP_001158116.1|refseq:NP_001158119.1|refseq:NP_005402.3|refseq:XP_005270119.1|refseq:XP_006718016.1|panther:PTHR24024(orthology-group)|efo:""Orphanet:2032"""	-	-	-	figure legend:2,3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/19	2024/11/14	rogid:LCxLkCvCyti2Ge9a2nZgoufrd2s272634	rogid:u2aN02hASKN0xgey/wmelcue4Xw9606	intact-crc:7E61B27AEAF9F76C|rigid:EVfUdbkNf81XhMNbnX8MtYth+Ts	false	35s radiolabel:?-?	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0821""(molecular weight estimation by autoradiography)"
uniprotkb:P75409	uniprotkb:Q8IWL2	intact:EBI-2259548|uniprotkb:Q1PD42|uniprotkb:Q1PD43|uniprotkb:Q1PD44|uniprotkb:Q1PD45|uniprotkb:Q1PD46	intact:EBI-11316418|uniprotkb:Q14DV4|uniprotkb:Q5RIR5|uniprotkb:Q5RIR7|uniprotkb:Q6PIT0|uniprotkb:Q8TC19|uniprotkb:A8K3T8|uniprotkb:B7ZW50|uniprotkb:E3VLD8|uniprotkb:E3VLD9|uniprotkb:E3VLE0|uniprotkb:E3VLE1|uniprotkb:G5E9J3|uniprotkb:P07714|ensembl:ENSP00000381633.3|ensembl:ENSP00000411102.2	psi-mi:cards_mycpn(display_long)|uniprotkb:cards(gene name)|psi-mi:cards(display_short)|uniprotkb:ADP-ribosyltransferase CARDS(gene name synonym)|uniprotkb:Community-Acquired Respiratory Distress Syndrome Toxin(gene name synonym)|uniprotkb:MP464(orf name)|uniprotkb:MPN_372(locus name)	psi-mi:sfta1_human(display_long)|uniprotkb:Alveolar proteinosis protein(gene name synonym)|uniprotkb:Collectin-4(gene name synonym)|uniprotkb:35 kDa pulmonary surfactant-associated protein(gene name synonym)|uniprotkb:SFTPA1(gene name)|psi-mi:SFTPA1(display_short)|uniprotkb:COLEC4(gene name synonym)|uniprotkb:PSAP(gene name synonym)|uniprotkb:SFTP1(gene name synonym)|uniprotkb:SFTPA(gene name synonym)|uniprotkb:SFTPA1B(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Kannan et al. (2005)	pubmed:15845487|imex:IM-25892	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13483429|imex:IM-25892-3	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003898(Bordetella pertussis toxin A)|refseq:NP_110060.1|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008289""(lipid binding)|go:""GO:0009986""(cell surface)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0033099""(attachment organelle)|go:""GO:0042995""(cell projection)|go:""GO:0044075""(symbiont-mediated perturbation of host vacuole organization)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0090729""(toxin activity)|interpro:IPR055042|interpro:IPR055043|refseq:WP_010874728.1|rcsb pdb:4TLV|rcsb pdb:4TLW"	"ensembl:ENSG00000122852.15(gene)|ensembl:ENST00000398636.8(transcript)|ensembl:ENST00000428376.6(transcript)|go:""GO:0005319""(lipid transporter activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0005771""(multivesicular body)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007585""(respiratory gaseous exchange by respiratory system)|go:""GO:0008228""(opsonization)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0042599""(lamellar body)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033990|interpro:IPR051663|reactome:R-HSA-166016|reactome:R-HSA-168179|reactome:R-HSA-391160|reactome:R-HSA-5683826|reactome:R-HSA-5686938|reactome:R-HSA-5688849|reactome:R-HSA-5688890|refseq:NP_001087239.2|refseq:NP_001158116.1|refseq:NP_001158119.1|refseq:NP_005402.3|refseq:XP_005270119.1|refseq:XP_006718016.1|panther:PTHR24024(orthology-group)|efo:""Orphanet:2032"""	-	-	-	figure legend:5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/19	2024/11/14	rogid:LCxLkCvCyti2Ge9a2nZgoufrd2s272634	rogid:u2aN02hASKN0xgey/wmelcue4Xw9606	intact-crc:231CBC3C32062BBC|rigid:EVfUdbkNf81XhMNbnX8MtYth+Ts	false	his tag:?-?	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P0C1U8	uniprotkb:P04275	intact:EBI-13644468|uniprotkb:P04188	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:sspa_staau(display_long)|uniprotkb:sspA(gene name)|psi-mi:sspA(display_short)|uniprotkb:Endoproteinase Glu-C(gene name synonym)|uniprotkb:Staphylococcal serine proteinase(gene name synonym)|uniprotkb:V8 protease(gene name synonym)|uniprotkb:V8 proteinase(gene name synonym)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Muia et al. (2014)	pubmed:25512528|imex:IM-25704	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0570""(protein cleavage)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13644441|imex:IM-25704-6	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000676548.1|rcsb pdb:1WCZ|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR008256(Peptidase S1B, glutamyl endopeptidase I)|interpro:IPR008353(Peptidase S1B, exfoliative toxin)|interpro:IPR028301|interpro:IPR000126(Peptidase S1B, active site)|interpro:IPR043504|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|interpro:IPR050966"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	-	-	-	figure legend:Supp 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/09	2025/02/28	rogid:rHzJh2LTQyMsBtFeuoiMViei0NM1280	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:A73B59549E658D03|rigid:vaOwE7pk4mJ5lf9esqQ3Dc/oFAw	false	-	sufficient binding region:?-?	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:P0C1U8	uniprotkb:P04275	intact:EBI-13644468|uniprotkb:P04188	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:sspa_staau(display_long)|uniprotkb:sspA(gene name)|psi-mi:sspA(display_short)|uniprotkb:Endoproteinase Glu-C(gene name synonym)|uniprotkb:Staphylococcal serine proteinase(gene name synonym)|uniprotkb:V8 protease(gene name synonym)|uniprotkb:V8 proteinase(gene name synonym)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Muia et al. (2014)	pubmed:25512528|imex:IM-25704	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0570""(protein cleavage)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13644441|imex:IM-25704-6	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000676548.1|rcsb pdb:1WCZ|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR008256(Peptidase S1B, glutamyl endopeptidase I)|interpro:IPR008353(Peptidase S1B, exfoliative toxin)|interpro:IPR028301|interpro:IPR000126(Peptidase S1B, active site)|interpro:IPR043504|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|interpro:IPR050966"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	-	-	-	figure legend:Supp 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/09	2025/02/28	rogid:rHzJh2LTQyMsBtFeuoiMViei0NM1280	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:A73B59549E658D03|rigid:vaOwE7pk4mJ5lf9esqQ3Dc/oFAw	false	-	sufficient binding region:?-?	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:P42081-1	uniprotkb:P01552	intact:EBI-16182989|ensembl:ENSP00000332049.2	intact:EBI-1027464	psi-mi:p42081-1(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Levy et al. (2016)	pubmed:27708164|imex:IM-26134	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-16182758|imex:IM-26134-21	intact-miscore:0.27	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1030956(isoform-parent)|ensembl:ENSG00000114013.16(gene)|ensembl:ENST00000330540.7(transcript)	"refseq:WP_000278085.1|dip:DIP-35541N|go:""GO:0005576""(extracellular region)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006173(Staphylococcal/Streptococcal toxin, OB-fold)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO"	"go:""GO:0009986""(cell surface)"	-	-	figure legend:2A|comment:Colocalization of SEB with cell-surface B7-2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/13	2024/11/14	rogid:VMDr9AcMwoSX2JyeGy7C0IcHXnY9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	intact-crc:0FAA5AD750C7D52E|rigid:YxK4X6iwaLhi91XLI2rgO2xGjSY	false	green fluorescent protein tag:c-c|sufficient binding region:?-?	sufficient binding region:177-188|alexa label:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P42081-3	uniprotkb:P01552	intact:EBI-15945259|ensembl:ENSP00000377248.2	intact:EBI-1027464	psi-mi:p42081-3(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Levy et al. (2016)	pubmed:27708164|imex:IM-26134	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-16190131|imex:IM-26134-1	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1030956(isoform-parent)|ensembl:ENSG00000114013.16(gene)|ensembl:ENST00000393627.6(transcript)	"refseq:WP_000278085.1|dip:DIP-35541N|go:""GO:0005576""(extracellular region)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006173(Staphylococcal/Streptococcal toxin, OB-fold)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO"	-	-	-	figure legend:2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/13	2024/11/14	rogid:ip4sFEhQ26nzCxD3D8xF7wPkVUY9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	intact-crc:1A9DF116A9AF0778|rigid:mqAb7AnGLjjEqm0YiMMlaFHmXxM	false	fc-igg tag:c-c|sufficient binding region:20-239|his tag:c-c	sufficient binding region:177-188	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P42081-3	uniprotkb:P01552	intact:EBI-15945259|ensembl:ENSP00000377248.2	intact:EBI-1027464	psi-mi:p42081-3(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Levy et al. (2016)	pubmed:27708164|imex:IM-26134	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-16192515|imex:IM-26134-3	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1030956(isoform-parent)|ensembl:ENSG00000114013.16(gene)|ensembl:ENST00000393627.6(transcript)	"refseq:WP_000278085.1|dip:DIP-35541N|go:""GO:0005576""(extracellular region)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006173(Staphylococcal/Streptococcal toxin, OB-fold)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO"	-	-	-	figure legend:2C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.4x10^-6(molar)	2017/06/13	2024/11/14	rogid:ip4sFEhQ26nzCxD3D8xF7wPkVUY9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	intact-crc:615AE0892D6AF124|rigid:mqAb7AnGLjjEqm0YiMMlaFHmXxM	false	fc-igg tag:c-c|sufficient binding region:20-239|his tag:c-c	sufficient binding region:177-188	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P42081-3	uniprotkb:P01552	intact:EBI-15945259|ensembl:ENSP00000377248.2	intact:EBI-1027464	psi-mi:p42081-3(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Levy et al. (2016)	pubmed:27708164|imex:IM-26134	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-16201294|imex:IM-26134-9	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1030956(isoform-parent)|ensembl:ENSG00000114013.16(gene)|ensembl:ENST00000393627.6(transcript)	"refseq:WP_000278085.1|dip:DIP-35541N|go:""GO:0005576""(extracellular region)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006173(Staphylococcal/Streptococcal toxin, OB-fold)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO"	-	-	-	figure legend:5A, Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.32x10^-6(molar)	2017/06/13	2024/11/14	rogid:ip4sFEhQ26nzCxD3D8xF7wPkVUY9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	intact-crc:5156135231E14B30|rigid:mqAb7AnGLjjEqm0YiMMlaFHmXxM	false	sufficient binding region:67-77	sufficient binding region:177-188	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P42081-3	uniprotkb:P01552	intact:EBI-15945259|ensembl:ENSP00000377248.2	intact:EBI-1027464	psi-mi:p42081-3(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Levy et al. (2016)	pubmed:27708164|imex:IM-26134	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-16202325|imex:IM-26134-11	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1030956(isoform-parent)|ensembl:ENSG00000114013.16(gene)|ensembl:ENST00000393627.6(transcript)	"refseq:WP_000278085.1|dip:DIP-35541N|go:""GO:0005576""(extracellular region)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006173(Staphylococcal/Streptococcal toxin, OB-fold)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO"	-	-	-	figure legend:5B, Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.9x10^-6(molar)	2017/06/13	2024/11/14	rogid:ip4sFEhQ26nzCxD3D8xF7wPkVUY9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	intact-crc:AE9810ACA88DE728|rigid:mqAb7AnGLjjEqm0YiMMlaFHmXxM	false	sufficient binding region:83-90	sufficient binding region:177-188	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P42081-3	uniprotkb:P06886-PRO_0000035619	intact:EBI-15945259|ensembl:ENSP00000377248.2	intact:EBI-16211350	psi-mi:p42081-3(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:p06886-pro_0000035619(display_long)|uniprotkb:tst(gene name)|psi-mi:tst(display_short)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Levy et al. (2016)	pubmed:27708164|imex:IM-26134	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-16203758|imex:IM-26134-13	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1030956(isoform-parent)|ensembl:ENSG00000114013.16(gene)|ensembl:ENST00000393627.6(transcript)	intact:EBI-7247529(chain-parent)	-	-	chain-seq-start:41|chain-seq-end:234	figure legend:Supp fig 4 A, Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:9.8x10^-6(molar)	2017/06/13	2024/11/14	rogid:ip4sFEhQ26nzCxD3D8xF7wPkVUY9606	rogid:JrzpL5fnG5JJ/ZBFotqe84U32WQ1280	intact-crc:A05409996A741C64|rigid:AzSjTHzpjvhcX8hmbJppyv5oTIo	false	sufficient binding region:67-77	his tag:n-n	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P42081-3	uniprotkb:P06886-PRO_0000035619	intact:EBI-15945259|ensembl:ENSP00000377248.2	intact:EBI-16211350	psi-mi:p42081-3(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:p06886-pro_0000035619(display_long)|uniprotkb:tst(gene name)|psi-mi:tst(display_short)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Levy et al. (2016)	pubmed:27708164|imex:IM-26134	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-16211559|imex:IM-26134-15	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1030956(isoform-parent)|ensembl:ENSG00000114013.16(gene)|ensembl:ENST00000393627.6(transcript)	intact:EBI-7247529(chain-parent)	-	-	chain-seq-start:41|chain-seq-end:234	figure legend:Supp fig 4B, Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.2x10^-6(molar)	2017/06/13	2024/11/14	rogid:ip4sFEhQ26nzCxD3D8xF7wPkVUY9606	rogid:JrzpL5fnG5JJ/ZBFotqe84U32WQ1280	intact-crc:9C2B979406DF7584|rigid:AzSjTHzpjvhcX8hmbJppyv5oTIo	false	sufficient binding region:83-90	his tag:n-n	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P42081-3	uniprotkb:Q99XW1	intact:EBI-15945259|ensembl:ENSP00000377248.2	intact:EBI-16212640|uniprotkb:Q48WF5	psi-mi:p42081-3(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:q99xw1_strp1(display_long)|uniprotkb:smeZ(gene name)|psi-mi:smeZ(display_short)|uniprotkb:SPy_1998(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Levy et al. (2016)	pubmed:27708164|imex:IM-26134	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-16212631|imex:IM-26134-17	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1030956(isoform-parent)|ensembl:ENSG00000114013.16(gene)|ensembl:ENST00000393627.6(transcript)	"interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006173(Staphylococcal/Streptococcal toxin, OB-fold)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|refseq:NP_269959.1|go:""GO:0005576""(extracellular region)|go:""GO:0090729""(toxin activity)"	-	-	-	figure legend:Supp fig 4 C, Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.3x10^-6(molar)	2017/06/13	2024/11/14	rogid:ip4sFEhQ26nzCxD3D8xF7wPkVUY9606	rogid:IxDrRJRa8hPSVF/GuxWO1k8jHVc301447	intact-crc:F94D503E6AB1D95C|rigid:qvDfMC9htQNU6jotebztIs4Bbx0	false	sufficient binding region:67-77	sufficient binding region:?-?|his tag:n-n	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P42081-3	uniprotkb:Q99XW1	intact:EBI-15945259|ensembl:ENSP00000377248.2	intact:EBI-16212640|uniprotkb:Q48WF5	psi-mi:p42081-3(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:q99xw1_strp1(display_long)|uniprotkb:smeZ(gene name)|psi-mi:smeZ(display_short)|uniprotkb:SPy_1998(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Levy et al. (2016)	pubmed:27708164|imex:IM-26134	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-16212704|imex:IM-26134-19	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1030956(isoform-parent)|ensembl:ENSG00000114013.16(gene)|ensembl:ENST00000393627.6(transcript)	"interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006173(Staphylococcal/Streptococcal toxin, OB-fold)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|refseq:NP_269959.1|go:""GO:0005576""(extracellular region)|go:""GO:0090729""(toxin activity)"	-	-	-	figure legend:Supp fig 4D, Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.8x10^-6(molar)	2017/06/13	2024/11/14	rogid:ip4sFEhQ26nzCxD3D8xF7wPkVUY9606	rogid:IxDrRJRa8hPSVF/GuxWO1k8jHVc301447	intact-crc:7964C14A5B867590|rigid:qvDfMC9htQNU6jotebztIs4Bbx0	false	sufficient binding region:83-90	his tag:n-n|sufficient binding region:?-?	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P42081-3	uniprotkb:P01552	intact:EBI-15945259|ensembl:ENSP00000377248.2	intact:EBI-1027464	psi-mi:p42081-3(display_long)|uniprotkb:CD86(gene name)|psi-mi:CD86(display_short)|uniprotkb:CD28LG2(gene name synonym)|uniprotkb:Activation B7-2 antigen(gene name synonym)|uniprotkb:B70(gene name synonym)|uniprotkb:BU63(gene name synonym)|uniprotkb:CTLA-4 counter-receptor B7.2(gene name synonym)|uniprotkb:FUN-1(gene name synonym)	psi-mi:etxb_staau(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:SEB(gene name synonym)	"psi-mi:""MI:1247""(microscale thermophoresis)"	Levy et al. (2016)	pubmed:27708164|imex:IM-26134	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-16192902|imex:IM-26134-5	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1030956(isoform-parent)|ensembl:ENSG00000114013.16(gene)|ensembl:ENST00000393627.6(transcript)	"refseq:WP_000278085.1|dip:DIP-35541N|go:""GO:0005576""(extracellular region)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR006173(Staphylococcal/Streptococcal toxin, OB-fold)|interpro:IPR006177(Toxin, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1GOZ|rcsb pdb:1SBB|rcsb pdb:1SE3|rcsb pdb:1SE4|rcsb pdb:1SEB|rcsb pdb:2SEB|rcsb pdb:3GP7|rcsb pdb:3R8B|rcsb pdb:3SEB|rcsb pdb:3W2D|rcsb pdb:4C56|rcsb pdb:4RGM|rcsb pdb:4RGN|rcsb pdb:4RGO"	-	-	-	figure legend:2D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.9x10^-6(molar)	2017/06/13	2024/11/14	rogid:ip4sFEhQ26nzCxD3D8xF7wPkVUY9606	rogid:G84qGHuyDP7GpWBh5Jvkzra5PsA1280	intact-crc:70DAE3A0E70B48CE|rigid:mqAb7AnGLjjEqm0YiMMlaFHmXxM	false	fc-igg tag:c-c|sufficient binding region:20-239|his tag:c-c	sufficient binding region:177-188|mutation disrupting interaction strength:177-177,179-179	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P68366	uniprotkb:Q4G4D4	intact:EBI-351772|uniprotkb:A8MUB1|uniprotkb:P05215|uniprotkb:B3KNQ6|ensembl:ENSP00000248437.4|intact:EBI-11134566	intact:EBI-15480291	psi-mi:tba4a_human(display_long)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Testis-specific alpha-tubulin(gene name synonym)|uniprotkb:Tubulin H2-alpha(gene name synonym)|uniprotkb:TUBA1(gene name synonym)	psi-mi:q4g4d4_edwta(display_long)|uniprotkb:eseG(gene name)|psi-mi:eseG(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Xie et al. (2010)	pubmed:20855515|imex:IM-25987	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:636(edwta)|taxid:636(Edwardsiella tarda)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-15480304|imex:IM-25987-3	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005991.1|refseq:NP_001265481.1|ensembl:ENSG00000127824.15(gene)|ensembl:ENST00000248437.9(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68366|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9833482|panther:PTHR11588(orthology-group)"	"go:""GO:0016020""(membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0033644""(host cell membrane)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)"	"go:""GO:0005829""(cytosol)"	-	-	figure legend:5B, 6|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293a)|taxid:9606(Homo sapiens HEK293A embryonic kidney cell)	-	2017/06/14	2024/11/14	rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9606	rogid:nzPZIxr9yUzZfzjDZlHydhP4Rvo636	intact-crc:FFDB3F335EFB922B|rigid:wXcQ2WGw2VPE7J6nmSyjFgoMlaU	false	-	sufficient binding region:1-88|green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P02679	uniprotkb:P75358	intact:EBI-1034422|uniprotkb:P04469|uniprotkb:P04470|uniprotkb:Q96A14|uniprotkb:Q96KJ3|ensembl:ENSP00000336829.3|uniprotkb:A8K057|uniprotkb:Q53Y18|uniprotkb:Q9UC62|uniprotkb:Q9UC63|uniprotkb:Q9UCF3	intact:EBI-2259469	psi-mi:fibg_human(display_long)|uniprotkb:FGG(gene name)|psi-mi:FGG(display_short)|uniprotkb:PRO2061(orf name)	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Dumke et al. (2011)	pubmed:21546586|imex:IM-25932	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13643920|imex:IM-25932-1	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000171557.17(gene)|ensembl:ENST00000336098.8(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0009306""(protein secretion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0036345""(platelet maturation)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042802""(identical protein binding)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0046872""(metal ion binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051592""(response to calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0072378""(blood coagulation, fibrin clot formation)|go:""GO:0072562""(blood microparticle)|go:""GO:0090277""(positive regulation of peptide hormone secretion)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037579|mint:P02679|rcsb pdb:1DUG|rcsb pdb:1FIB|rcsb pdb:1FIC|rcsb pdb:1FID|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2FIB|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2HWL|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2VDO|rcsb pdb:2VDP|rcsb pdb:2VDQ|rcsb pdb:2VDR|rcsb pdb:2VR3|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Y7L|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3FIB|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4B60|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_000500.2|refseq:NP_068656.2|efo:""Orphanet:101041""|efo:""Orphanet:248408""|efo:""Orphanet:98880""|efo:""Orphanet:98881""|dip:DIP-29644N|panther:PTHR19143(orthology-group)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	-	-	-	figure legend:5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/09	2025/03/26	rogid:QKWesyU4/fduceFtu5zq31oGhYI9606	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	intact-crc:83F3FEEA34078380|rigid:w07KcQa+jXgylNAANG+aFJmyEUg	false	-	his tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P02679	uniprotkb:P75358	intact:EBI-1034422|uniprotkb:P04469|uniprotkb:P04470|uniprotkb:Q96A14|uniprotkb:Q96KJ3|ensembl:ENSP00000336829.3|uniprotkb:A8K057|uniprotkb:Q53Y18|uniprotkb:Q9UC62|uniprotkb:Q9UC63|uniprotkb:Q9UCF3	intact:EBI-2259469	psi-mi:fibg_human(display_long)|uniprotkb:FGG(gene name)|psi-mi:FGG(display_short)|uniprotkb:PRO2061(orf name)	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Dumke et al. (2011)	pubmed:21546586|imex:IM-25932	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13643930|imex:IM-25932-3	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000171557.17(gene)|ensembl:ENST00000336098.8(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0009306""(protein secretion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0036345""(platelet maturation)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042802""(identical protein binding)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0046872""(metal ion binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051592""(response to calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0072378""(blood coagulation, fibrin clot formation)|go:""GO:0072562""(blood microparticle)|go:""GO:0090277""(positive regulation of peptide hormone secretion)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037579|mint:P02679|rcsb pdb:1DUG|rcsb pdb:1FIB|rcsb pdb:1FIC|rcsb pdb:1FID|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2FIB|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2HWL|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2VDO|rcsb pdb:2VDP|rcsb pdb:2VDQ|rcsb pdb:2VDR|rcsb pdb:2VR3|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Y7L|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3FIB|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4B60|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_000500.2|refseq:NP_068656.2|efo:""Orphanet:101041""|efo:""Orphanet:248408""|efo:""Orphanet:98880""|efo:""Orphanet:98881""|dip:DIP-29644N|panther:PTHR19143(orthology-group)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	-	-	-	figure legend:5C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/09	2025/03/26	rogid:QKWesyU4/fduceFtu5zq31oGhYI9606	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	intact-crc:40FB313CEA6D6A88|rigid:w07KcQa+jXgylNAANG+aFJmyEUg	false	-	his tag:n-n	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13643953|imex:IM-25930-21	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/09	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:33C8B1F21FA07907|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13643965|imex:IM-25930-1	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-mgc-803)|taxid:9606(Homo sapiens MGC-803 gastric carcinoma cell)	-	2017/02/09	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:9EEDC6B65EE78BC3|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13644052|imex:IM-25930-11	intact-miscore:0.78	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:6B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-mgc-803)|taxid:9606(Homo sapiens MGC-803 gastric carcinoma cell)	-	2017/02/09	2025/03/24	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:F3A5555D6D18303A|rigid:uU9rdkFDuwFygudcIONyTLI2/TM	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P15363	uniprotkb:P00533	intact:EBI-12740262	intact:EBI-297353|uniprotkb:Q9BZS2|uniprotkb:Q9GZX1|uniprotkb:Q9H2C9|uniprotkb:Q9H3C9|uniprotkb:Q9UMD7|uniprotkb:Q9UMD8|uniprotkb:Q9UMG5|uniprotkb:O00688|uniprotkb:O00732|uniprotkb:P06268|uniprotkb:Q14225|uniprotkb:Q92795|intact:EBI-28985169|uniprotkb:Q68GS5|ensembl:ENSP00000275493.2	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:egfr_human(display_long)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:ERBB(gene name synonym)|uniprotkb:HER1(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13644052|imex:IM-25930-11	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"ensembl:ENSG00000146648.21(gene)|ensembl:ENST00000275493.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001503""(ossification)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001942""(hair follicle development)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007435""(salivary gland morphogenesis)|go:""GO:0007494""(midgut development)|go:""GO:0007611""(learning or memory)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016101""(diterpenoid metabolic process)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0022008""(neurogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0033594""(response to hydroxyisoflavone)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038134""(ERBB2-EGFR signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042311""(vasodilation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042698""(ovulation cycle)|go:""GO:0042743""(hydrogen peroxide metabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0043586""(tongue development)|go:""GO:0045121""(membrane raft)|go:""GO:0045296""(cadherin binding)|go:""GO:0045737""(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048143""(astrocyte activation)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048408""(epidermal growth factor binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048546""(digestive tract morphogenesis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051015""(actin filament binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051205""(protein insertion into membrane)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051968""(positive regulation of synaptic transmission, glutamatergic)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060571""(morphogenesis of an epithelial fold)|go:""GO:0061029""(eyelid development in camera-type eye)|go:""GO:0070141""(response to UV-A)|go:""GO:0070257""(positive regulation of mucus secretion)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070435""(Shc-EGFR complex)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097421""(liver regeneration)|go:""GO:0097489""(multivesicular body, internal vesicle lumen)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900020""(positive regulation of protein kinase C activity)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|go:""GO:1902722""(positive regulation of prolactin secretion)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905208""(negative regulation of cardiocyte differentiation)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|interpro:IPR049328|interpro:IPR050122|mint:P00533|rcsb pdb:1IVO|rcsb pdb:1M14|rcsb pdb:1M17|rcsb pdb:1MOX|rcsb pdb:1NQL|rcsb pdb:1XKK|rcsb pdb:1YY9|rcsb pdb:1Z9I|rcsb pdb:2EB2|rcsb pdb:2EB3|rcsb pdb:2GS2|rcsb pdb:2GS6|rcsb pdb:2GS7|rcsb pdb:2ITN|rcsb pdb:2ITO|rcsb pdb:2ITP|rcsb pdb:2ITQ|rcsb pdb:2ITT|rcsb pdb:2ITU|rcsb pdb:2ITV|rcsb pdb:2ITW|rcsb pdb:2ITX|rcsb pdb:2ITY|rcsb pdb:2ITZ|rcsb pdb:2KS1|rcsb pdb:2J5E|rcsb pdb:2J5F|rcsb pdb:2J6M|rcsb pdb:2JIT|rcsb pdb:2JIU|rcsb pdb:2JIV|rcsb pdb:2M0B|rcsb pdb:2M20|rcsb pdb:2N5S|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:2RGP|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BEL|rcsb pdb:3BUO|rcsb pdb:3C09|rcsb pdb:3G5V|rcsb pdb:3G5Y|rcsb pdb:3GOP|rcsb pdb:3GT8|rcsb pdb:3IKA|rcsb pdb:3LZB|rcsb pdb:3NJP|rcsb pdb:3OB2|rcsb pdb:3OP0|rcsb pdb:3P0Y|rcsb pdb:3PFV|rcsb pdb:3POZ|rcsb pdb:3QWQ|rcsb pdb:3UG1|rcsb pdb:3UG2|rcsb pdb:3VJN|rcsb pdb:3VJO|rcsb pdb:3VRP|rcsb pdb:3VRR|rcsb pdb:3W2O|rcsb pdb:3W2P|rcsb pdb:3W2Q|rcsb pdb:3W2R|rcsb pdb:3W2S|rcsb pdb:3W32|rcsb pdb:3W33|rcsb pdb:4G5J|rcsb pdb:4G5P|rcsb pdb:4HJO|rcsb pdb:4I1Z|rcsb pdb:4I20|rcsb pdb:4I21|rcsb pdb:4I22|rcsb pdb:4I23|rcsb pdb:4I24|rcsb pdb:4JQ7|rcsb pdb:4JQ8|rcsb pdb:4JR3|rcsb pdb:4JRV|rcsb pdb:4KRL|rcsb pdb:4KRM|rcsb pdb:4KRO|rcsb pdb:4KRP|rcsb pdb:4LI5|rcsb pdb:4LL0|rcsb pdb:4LQM|rcsb pdb:4LRM|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4R5S|rcsb pdb:4RIW|rcsb pdb:4RIX|rcsb pdb:4RIY|rcsb pdb:4RJ4|rcsb pdb:4RJ5|rcsb pdb:4RJ6|rcsb pdb:4RJ7|rcsb pdb:4RJ8|rcsb pdb:4TKS|rcsb pdb:4UIP|rcsb pdb:4UV7|rcsb pdb:4WD5|rcsb pdb:4WKQ|rcsb pdb:4WRG|rcsb pdb:4ZAU|rcsb pdb:4ZJV|rcsb pdb:4ZSE|rcsb pdb:5C8K|rcsb pdb:5C8M|rcsb pdb:5C8N|rcsb pdb:5CAL|rcsb pdb:5CAN|rcsb pdb:5CAO|rcsb pdb:5CAP|rcsb pdb:5CAQ|rcsb pdb:5CAS|rcsb pdb:5CAU|rcsb pdb:5CAV|rcsb pdb:5CNN|rcsb pdb:5CNO|rcsb pdb:5CZH|rcsb pdb:5CZI|rcsb pdb:5D41|rcsb pdb:5EDP|rcsb pdb:5EDQ|rcsb pdb:5EDR|rcsb pdb:5EM5|rcsb pdb:5EM6|rcsb pdb:5EM7|rcsb pdb:5EM8|rcsb pdb:5FED|rcsb pdb:5FEE|rcsb pdb:5FEQ|rcsb pdb:5GMP|rcsb pdb:5GNK|rcsb pdb:5GTY|rcsb pdb:5GTZ|rcsb pdb:5HCX|rcsb pdb:5HCY|rcsb pdb:5HCZ|rcsb pdb:5HG5|rcsb pdb:5HG7|rcsb pdb:5HG8|rcsb pdb:5HG9|rcsb pdb:5HIB|rcsb pdb:5HIC|rcsb pdb:5J9Y|rcsb pdb:5J9Z|rcsb pdb:5JEB|rcsb pdb:5LV6|rcsb pdb:5SX4|rcsb pdb:5SX5|rcsb pdb:5U8L|rcsb pdb:5UG8|rcsb pdb:5UG9|rcsb pdb:5UGA|rcsb pdb:5UGB|rcsb pdb:5UGC|rcsb pdb:5UWD|rcsb pdb:5WB7|rcsb pdb:5WB8|rcsb pdb:5X26|rcsb pdb:5X27|rcsb pdb:5X28|rcsb pdb:5X2A|rcsb pdb:5X2C|rcsb pdb:5X2F|rcsb pdb:5X2K|rcsb pdb:5XDK|rcsb pdb:5XDL|rcsb pdb:5XGM|rcsb pdb:5XGN|rcsb pdb:5XWD|rcsb pdb:5Y25|rcsb pdb:5Y9T|rcsb pdb:5YU9|rcsb pdb:5ZTO|rcsb pdb:5ZWJ|rcsb pdb:6ARU|rcsb pdb:6B3S|rcsb pdb:6D8E|rcsb pdb:6DUK|rcsb pdb:6JRJ|rcsb pdb:6JRK|rcsb pdb:6JRX|rcsb pdb:6JWL|rcsb pdb:6JX0|rcsb pdb:6JX4|rcsb pdb:6JXT|rcsb pdb:6JZ0|rcsb pdb:6LUB|rcsb pdb:6LUD|rcsb pdb:6P1D|rcsb pdb:6P1L|rcsb pdb:6P8Q|rcsb pdb:6S89|rcsb pdb:6S8A|rcsb pdb:6S9B|rcsb pdb:6S9C|rcsb pdb:6S9D|rcsb pdb:6TFU|rcsb pdb:6TFV|rcsb pdb:6TFW|rcsb pdb:6TFY|rcsb pdb:6TFZ|rcsb pdb:6TG0|rcsb pdb:6TG1|rcsb pdb:6V5N|rcsb pdb:6V5P|rcsb pdb:6V66|rcsb pdb:6V6K|rcsb pdb:6V6O|rcsb pdb:6VH4|rcsb pdb:6VHN|rcsb pdb:6VHP|rcsb pdb:6WA2|rcsb pdb:6WAK|rcsb pdb:6WXN|rcsb pdb:6XL4|rcsb pdb:6Z4B|rcsb pdb:6Z4D|rcsb pdb:7A2A|rcsb pdb:7A6I|rcsb pdb:7A6J|rcsb pdb:7A6K|rcsb pdb:7AEI|rcsb pdb:7AEM|rcsb pdb:7B85|rcsb pdb:7ER2|rcsb pdb:7JXI|rcsb pdb:7JXK|rcsb pdb:7JXL|rcsb pdb:7JXM|rcsb pdb:7JXP|rcsb pdb:7JXQ|rcsb pdb:7JXW|rcsb pdb:7K1H|rcsb pdb:7K1I|rcsb pdb:7KXZ|rcsb pdb:7KY0|rcsb pdb:7LEN|rcsb pdb:7LFR|rcsb pdb:7LFS|rcsb pdb:7LG8|rcsb pdb:7LGS|rcsb pdb:7LTX|rcsb pdb:7OM4|rcsb pdb:7OXB|rcsb pdb:7SI1|rcsb pdb:7SYD|rcsb pdb:7SYE|rcsb pdb:7SZ0|rcsb pdb:7SZ1|rcsb pdb:8A2B|rcsb pdb:7SZ5|rcsb pdb:7SZ7|rcsb pdb:7T4I|rcsb pdb:7T4J|rcsb pdb:7TVD|rcsb pdb:7U98|rcsb pdb:7U99|rcsb pdb:7U9A|rcsb pdb:7UKV|rcsb pdb:7UKW|rcsb pdb:7VRA|rcsb pdb:7VRE|rcsb pdb:7ZYM|rcsb pdb:7ZYN|rcsb pdb:7ZYP|rcsb pdb:7ZYQ|rcsb pdb:8A27|rcsb pdb:8A2A|rcsb pdb:8A2D|rcsb pdb:8D73|rcsb pdb:8D76|rcsb pdb:8DSW|rcsb pdb:8EME|rcsb pdb:8F1H|rcsb pdb:8F1W|rcsb pdb:8F1X|rcsb pdb:8F1Y|rcsb pdb:8F1Z|rcsb pdb:8FV3|rcsb pdb:8FV4|rcsb pdb:8G63|rcsb pdb:8GB4|rcsb pdb:8GK5|rcsb pdb:8H7X|rcsb pdb:8HGO|rcsb pdb:8HGP|rcsb pdb:8HGS|rcsb pdb:8HV1|rcsb pdb:8HV2|rcsb pdb:8HV3|rcsb pdb:8HV4|rcsb pdb:8HV5|rcsb pdb:8HV6|rcsb pdb:8HV7|rcsb pdb:8HV8|rcsb pdb:8HV9|rcsb pdb:8HVA|rcsb pdb:8HY7|rcsb pdb:8KFQ|rcsb pdb:8PNZ|rcsb pdb:8PO0|rcsb pdb:8PO1|rcsb pdb:8PO2|rcsb pdb:8PO3|rcsb pdb:8PO4|rcsb pdb:8S1M|rcsb pdb:8SC7|rcsb pdb:8TJL|rcsb pdb:8TO3|rcsb pdb:8TO4|rcsb pdb:8UKV|rcsb pdb:8UKW|rcsb pdb:8UKX|rcsb pdb:8WD4|rcsb pdb:9EWT|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-212718|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-445144|reactome:R-HSA-5637810|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8857538|reactome:R-HSA-8863795|reactome:R-HSA-8866910|reactome:R-HSA-9009391|reactome:R-HSA-9013507|reactome:R-HSA-9609690|reactome:R-HSA-9634638|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9820960|refseq:NP_005219.2|refseq:NP_958439.1|refseq:NP_958440.1|refseq:NP_958441.1|dip:DIP-405N|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:294023""|ensembl:ENSP00000275493.2|ensembl:ENST00000342916.7|ensembl:ENSP00000342376.3|ensembl:ENST00000344576.7|ensembl:ENSP00000345973.2|ensembl:ENST00000420316.6|ensembl:ENSP00000413843.2|panther:PTHR24416(orthology-group)"	-	-	-	figure legend:6B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-mgc-803)|taxid:9606(Homo sapiens MGC-803 gastric carcinoma cell)	-	2017/02/09	2025/03/24	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:gXB5slVTC+z8DdqqXIzXG7lDwk09606	intact-crc:F3A5555D6D18303A|rigid:uU9rdkFDuwFygudcIONyTLI2/TM	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-16086633|imex:IM-25930-27	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-mgc-803)|taxid:9606(Homo sapiens MGC-803 gastric carcinoma cell)	-	2017/02/09	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:BE9C7969668FE357|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13643978|imex:IM-25930-3	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4C, suppl 4D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2017/02/09	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:7CCB01CCBA204AEE|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P07355	uniprotkb:P15363	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-12740262	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13644057|imex:IM-25930-25	intact-miscore:0.78	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	-	-	-	figure legend:6C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2017/02/09	2025/03/24	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	intact-crc:006ED867A3329961|rigid:uU9rdkFDuwFygudcIONyTLI2/TM	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-16090125|imex:IM-25930-17	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:suppl 4E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2017/02/09	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:55423C99C46CF5F9|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13643989|imex:IM-25930-23	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/09	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:45069F5491961A3E|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	glutathione s tranferase tag:?-?|sufficient binding region:2-23	his tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13644000|imex:IM-25930-5	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/09	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:D28055D8C63E45E4|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	glutathione s tranferase tag:?-?	necessary binding region:2-26|his tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13644018|imex:IM-25930-7	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:4E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/09	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:042A166A36CC675E|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	glutathione s tranferase tag:?-?|necessary binding region:2-23	necessary binding region:2-26	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P07355	uniprotkb:P15363	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-12740262	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13644039|imex:IM-25930-9	intact-miscore:0.78	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	-	-	-	figure legend:4F|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/09	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	intact-crc:6C31EFDBAD09D160|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	his tag:?-?	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P07355	uniprotkb:P15363	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-12740262	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13644039|imex:IM-25930-9	intact-miscore:0.78	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	-	-	-	figure legend:4F|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/09	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	intact-crc:6C31EFDBAD09D160|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	his tag:?-?	sufficient binding region:2-23	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P07355	uniprotkb:P15363	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-12740262	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13644068|imex:IM-25930-13	intact-miscore:0.78	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	-	-	-	figure legend:6C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-mgc-803)|taxid:9606(Homo sapiens MGC-803 gastric carcinoma cell)	-	2017/02/09	2025/03/24	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	intact-crc:E11B89E097DFD746|rigid:uU9rdkFDuwFygudcIONyTLI2/TM	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-16090564|imex:IM-25930-19	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:suppl 4D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-mgc-803)|taxid:9606(Homo sapiens MGC-803 gastric carcinoma cell)	-	2017/02/09	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:BECADB16D67E47A8|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Duan et al. (2014)	pubmed:25136068|imex:IM-25930	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-16090568|imex:IM-25930-29	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:suppl 4E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-mgc-803)|taxid:9606(Homo sapiens MGC-803 gastric carcinoma cell)	-	2017/02/09	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:232E07D1507E048C|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P07355	uniprotkb:P75409	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-2259548|uniprotkb:Q1PD42|uniprotkb:Q1PD43|uniprotkb:Q1PD44|uniprotkb:Q1PD45|uniprotkb:Q1PD46	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:cards_mycpn(display_long)|uniprotkb:cards(gene name)|psi-mi:cards(display_short)|uniprotkb:ADP-ribosyltransferase CARDS(gene name synonym)|uniprotkb:Community-Acquired Respiratory Distress Syndrome Toxin(gene name synonym)|uniprotkb:MP464(orf name)|uniprotkb:MPN_372(locus name)	"psi-mi:""MI:0096""(pull down)"	Somarajan et al. (2014)	pubmed:25139904|imex:IM-25938	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13644973|imex:IM-25938-1	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"interpro:IPR003898(Bordetella pertussis toxin A)|refseq:NP_110060.1|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008289""(lipid binding)|go:""GO:0009986""(cell surface)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0033099""(attachment organelle)|go:""GO:0042995""(cell projection)|go:""GO:0044075""(symbiont-mediated perturbation of host vacuole organization)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0090729""(toxin activity)|interpro:IPR055042|interpro:IPR055043|refseq:WP_010874728.1|rcsb pdb:4TLV|rcsb pdb:4TLW"	-	-	-	figure legend:1A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:LCxLkCvCyti2Ge9a2nZgoufrd2s272634	intact-crc:041D2A8F2A3B4A93|rigid:E+WpoAS9sGvnkQ4HsGn5JslDzNk	false	-	his tag:n-n	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:P07355	uniprotkb:P75409	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-2259548|uniprotkb:Q1PD42|uniprotkb:Q1PD43|uniprotkb:Q1PD44|uniprotkb:Q1PD45|uniprotkb:Q1PD46	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:cards_mycpn(display_long)|uniprotkb:cards(gene name)|psi-mi:cards(display_short)|uniprotkb:ADP-ribosyltransferase CARDS(gene name synonym)|uniprotkb:Community-Acquired Respiratory Distress Syndrome Toxin(gene name synonym)|uniprotkb:MP464(orf name)|uniprotkb:MPN_372(locus name)	"psi-mi:""MI:0047""(far western blotting)"	Somarajan et al. (2014)	pubmed:25139904|imex:IM-25938	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13644993|imex:IM-25938-3	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"interpro:IPR003898(Bordetella pertussis toxin A)|refseq:NP_110060.1|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008289""(lipid binding)|go:""GO:0009986""(cell surface)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0033099""(attachment organelle)|go:""GO:0042995""(cell projection)|go:""GO:0044075""(symbiont-mediated perturbation of host vacuole organization)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0090729""(toxin activity)|interpro:IPR055042|interpro:IPR055043|refseq:WP_010874728.1|rcsb pdb:4TLV|rcsb pdb:4TLW"	-	-	-	figure legend:1B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:LCxLkCvCyti2Ge9a2nZgoufrd2s272634	intact-crc:4B49186AB7473823|rigid:E+WpoAS9sGvnkQ4HsGn5JslDzNk	false	-	his tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P07355	uniprotkb:P75409	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-2259548|uniprotkb:Q1PD42|uniprotkb:Q1PD43|uniprotkb:Q1PD44|uniprotkb:Q1PD45|uniprotkb:Q1PD46	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:cards_mycpn(display_long)|uniprotkb:cards(gene name)|psi-mi:cards(display_short)|uniprotkb:ADP-ribosyltransferase CARDS(gene name synonym)|uniprotkb:Community-Acquired Respiratory Distress Syndrome Toxin(gene name synonym)|uniprotkb:MP464(orf name)|uniprotkb:MPN_372(locus name)	"psi-mi:""MI:0047""(far western blotting)"	Somarajan et al. (2014)	pubmed:25139904|imex:IM-25938	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13645021|imex:IM-25938-5	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"interpro:IPR003898(Bordetella pertussis toxin A)|refseq:NP_110060.1|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008289""(lipid binding)|go:""GO:0009986""(cell surface)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0033099""(attachment organelle)|go:""GO:0042995""(cell projection)|go:""GO:0044075""(symbiont-mediated perturbation of host vacuole organization)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0090729""(toxin activity)|interpro:IPR055042|interpro:IPR055043|refseq:WP_010874728.1|rcsb pdb:4TLV|rcsb pdb:4TLW"	-	-	-	figure legend:2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:LCxLkCvCyti2Ge9a2nZgoufrd2s272634	intact-crc:039EA21BA3AC7C97|rigid:E+WpoAS9sGvnkQ4HsGn5JslDzNk	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P07355	uniprotkb:P75409	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-2259548|uniprotkb:Q1PD42|uniprotkb:Q1PD43|uniprotkb:Q1PD44|uniprotkb:Q1PD45|uniprotkb:Q1PD46	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:cards_mycpn(display_long)|uniprotkb:cards(gene name)|psi-mi:cards(display_short)|uniprotkb:ADP-ribosyltransferase CARDS(gene name synonym)|uniprotkb:Community-Acquired Respiratory Distress Syndrome Toxin(gene name synonym)|uniprotkb:MP464(orf name)|uniprotkb:MPN_372(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Somarajan et al. (2014)	pubmed:25139904|imex:IM-25938	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13645035|imex:IM-25938-7	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"interpro:IPR003898(Bordetella pertussis toxin A)|refseq:NP_110060.1|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008289""(lipid binding)|go:""GO:0009986""(cell surface)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0033099""(attachment organelle)|go:""GO:0042995""(cell projection)|go:""GO:0044075""(symbiont-mediated perturbation of host vacuole organization)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0090729""(toxin activity)|interpro:IPR055042|interpro:IPR055043|refseq:WP_010874728.1|rcsb pdb:4TLV|rcsb pdb:4TLW"	-	-	-	figure legend:3A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:LCxLkCvCyti2Ge9a2nZgoufrd2s272634	intact-crc:606A3F7BB7D6AD7D|rigid:E+WpoAS9sGvnkQ4HsGn5JslDzNk	false	glutathione s tranferase tag:n-n	his tag:n-n|sufficient binding region:266-591	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P07355	uniprotkb:P75409	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-2259548|uniprotkb:Q1PD42|uniprotkb:Q1PD43|uniprotkb:Q1PD44|uniprotkb:Q1PD45|uniprotkb:Q1PD46	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:cards_mycpn(display_long)|uniprotkb:cards(gene name)|psi-mi:cards(display_short)|uniprotkb:ADP-ribosyltransferase CARDS(gene name synonym)|uniprotkb:Community-Acquired Respiratory Distress Syndrome Toxin(gene name synonym)|uniprotkb:MP464(orf name)|uniprotkb:MPN_372(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Somarajan et al. (2014)	pubmed:25139904|imex:IM-25938	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13645058|imex:IM-25938-9	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"interpro:IPR003898(Bordetella pertussis toxin A)|refseq:NP_110060.1|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008289""(lipid binding)|go:""GO:0009986""(cell surface)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0033099""(attachment organelle)|go:""GO:0042995""(cell projection)|go:""GO:0044075""(symbiont-mediated perturbation of host vacuole organization)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0090729""(toxin activity)|interpro:IPR055042|interpro:IPR055043|refseq:WP_010874728.1|rcsb pdb:4TLV|rcsb pdb:4TLW"	-	-	-	"figure legend:2B & 3B|comment:""\""Truncated AnxA2 proteins (AnxA2267 (amino acids 1 to 267) and 268AnxA2 (amino acids 268 to 339) demonstrated higher binding to CARDS than when using the full AnxA2.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:LCxLkCvCyti2Ge9a2nZgoufrd2s272634	intact-crc:219084551059DCD4|rigid:E+WpoAS9sGvnkQ4HsGn5JslDzNk	false	glutathione s tranferase tag:n-n	his tag:n-n	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75409	uniprotkb:P07355	intact:EBI-2259548|uniprotkb:Q1PD42|uniprotkb:Q1PD43|uniprotkb:Q1PD44|uniprotkb:Q1PD45|uniprotkb:Q1PD46	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:cards_mycpn(display_long)|uniprotkb:cards(gene name)|psi-mi:cards(display_short)|uniprotkb:ADP-ribosyltransferase CARDS(gene name synonym)|uniprotkb:Community-Acquired Respiratory Distress Syndrome Toxin(gene name synonym)|uniprotkb:MP464(orf name)|uniprotkb:MPN_372(locus name)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Somarajan et al. (2014)	pubmed:25139904|imex:IM-25938	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13645079|imex:IM-25938-11	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003898(Bordetella pertussis toxin A)|refseq:NP_110060.1|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008289""(lipid binding)|go:""GO:0009986""(cell surface)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0033099""(attachment organelle)|go:""GO:0042995""(cell projection)|go:""GO:0044075""(symbiont-mediated perturbation of host vacuole organization)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0090729""(toxin activity)|interpro:IPR055042|interpro:IPR055043|refseq:WP_010874728.1|rcsb pdb:4TLV|rcsb pdb:4TLW"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"go:""GO:0009986""(cell surface)"	-	-	figure legend:5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-a_549)|taxid:9606(Homo sapiens A549 lung carcinoma cell)	-	2017/02/10	2024/11/14	rogid:LCxLkCvCyti2Ge9a2nZgoufrd2s272634	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:48529478FA24754E|rigid:E+WpoAS9sGvnkQ4HsGn5JslDzNk	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P00747	uniprotkb:P75390	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-2259629	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	"psi-mi:""MI:0047""(far western blotting)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13916019|imex:IM-26051-1	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	-	-	-	figure legend:4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	intact-crc:0261C2F82BA2049C|rigid:pMM/RJTnIsj6CPlD4V89Tdars2Y	false	-	his tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P00747	uniprotkb:P75391	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-2259621	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	"psi-mi:""MI:0047""(far western blotting)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13916025|imex:IM-26051-3	intact-miscore:0.83	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	-	-	-	figure legend:4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	intact-crc:86D0E4407D8DE073|rigid:rbpPnM94cb3alyoiXVn/sGuf2U8	false	-	his tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P00747	uniprotkb:P75392	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-2259593	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	"psi-mi:""MI:0047""(far western blotting)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13916031|imex:IM-26051-5	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	-	-	-	figure legend:4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	intact-crc:BB038F8887FDCD43|rigid:eS02w0gHvYCoXmR1a3oFRkvl02s	false	-	his tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P00747	uniprotkb:P75393	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-2259617	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:dldh_mycpn(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:E3 component of pyruvate complex(gene name synonym)|uniprotkb:MP448(orf name)|uniprotkb:MPN_390(locus name)|uniprotkb:pdhD(gene name)|psi-mi:pdhD(display_short)	"psi-mi:""MI:0047""(far western blotting)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13916037|imex:IM-26051-7	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"refseq:NP_110078.1|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR050151|refseq:WP_010874746.1|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR036188"	-	-	-	figure legend:4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:Eb1Sg/tY1YhSGOWF0ZGBbjJIFPw272634	intact-crc:3FB2A930D1D229AC|rigid:cNCm0iFh0MB2U0DivJiwfM4XHp4	false	-	his tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P75391	uniprotkb:P00747	intact:EBI-2259621	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13916049|imex:IM-26051-18	intact-miscore:0.83	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:4B and 5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:AF0A414B458CC29B	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75390	uniprotkb:P00747	intact:EBI-2259629	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13916055|imex:IM-26051-20	intact-miscore:0.66	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:4B and 5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:7094B476B0022ED9	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75392	uniprotkb:P00747	intact:EBI-2259593	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13916061|imex:IM-26051-22	intact-miscore:0.66	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:4B and 5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:16255148989407BB	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P00747	uniprotkb:P75393	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-2259617	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:dldh_mycpn(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:E3 component of pyruvate complex(gene name synonym)|uniprotkb:MP448(orf name)|uniprotkb:MPN_390(locus name)|uniprotkb:pdhD(gene name)|psi-mi:pdhD(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13916067|imex:IM-26051-13	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"refseq:NP_110078.1|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR050151|refseq:WP_010874746.1|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR036188"	-	-	-	figure legend:4B and 5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:Eb1Sg/tY1YhSGOWF0ZGBbjJIFPw272634	intact-crc:715FCFAC6292554A|rigid:cNCm0iFh0MB2U0DivJiwfM4XHp4	false	-	his tag:n-n	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75390	uniprotkb:P00747	intact:EBI-2259629	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13939362|imex:IM-26051-24	intact-miscore:0.66	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:4B and 5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:9C52B3D451C7D62A	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75392	uniprotkb:P00747	intact:EBI-2259593	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13939369|imex:IM-26051-26	intact-miscore:0.66	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:4B and 5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:FAE356EA7951FF48	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P00747	uniprotkb:P75391	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-2259621	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13939376|imex:IM-26051-15	intact-miscore:0.83	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	-	-	-	"figure legend:4, 5B|comment:""\""e-aminocaproic acid (ACA) did not affect interaction with the P3 peptide\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	intact-crc:06645EBCBC6ACFCB|rigid:rbpPnM94cb3alyoiXVn/sGuf2U8	false	-	his tag:n-n|sufficient binding region:91-102	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75393	uniprotkb:P00747	intact:EBI-2259617	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:dldh_mycpn(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:E3 component of pyruvate complex(gene name synonym)|uniprotkb:MP448(orf name)|uniprotkb:MPN_390(locus name)|uniprotkb:pdhD(gene name)|psi-mi:pdhD(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940253|imex:IM-26051-28	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110078.1|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR050151|refseq:WP_010874746.1|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR036188"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:4B and 5i|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:Eb1Sg/tY1YhSGOWF0ZGBbjJIFPw272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:DFA5CBA4756D1AEB	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P00747	uniprotkb:P75390	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-2259629	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940260|imex:IM-26051-11	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	-	-	-	figure legend:4B and 5i|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	intact-crc:8548C6D80D5E4F68|rigid:pMM/RJTnIsj6CPlD4V89Tdars2Y	false	-	his tag:n-n	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P00747	uniprotkb:P75392	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-2259593	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940267|imex:IM-26051-17	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	-	-	-	figure legend:4B and 5i|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	intact-crc:DC4E773D3376D941|rigid:eS02w0gHvYCoXmR1a3oFRkvl02s	false	-	his tag:n-n	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P00747	intact:EBI-2259621	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0990""(cleavage assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13939393|imex:IM-26051-9	intact-miscore:0.83	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0840""(stimulator)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:6A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2025/01/27	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:9DFE65EB4F5EA07A|rigid:PSy9/vZhGogv+U+VGJQbD/hKSyU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P75391	uniprotkb:P00749	intact:EBI-2259621	intact:EBI-3905042|uniprotkb:Q15844|uniprotkb:B4DPZ2|uniprotkb:Q53XS3|uniprotkb:Q16618|uniprotkb:Q5SWW9|uniprotkb:Q969W6|ensembl:ENSP00000361850.3	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:urok_human(display_long)|uniprotkb:PLAU(gene name)|psi-mi:PLAU(display_short)	"psi-mi:""MI:0990""(cleavage assay)"	Gründel et al. (2014)	pubmed:25978044|imex:IM-26051	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13939393|imex:IM-26051-9	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0840""(stimulator)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"dip:DIP-46387N|ensembl:ENSG00000122861.16(gene)|ensembl:ENST00000372764.4(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006508""(proteolysis)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0007596""(blood coagulation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010469""(regulation of signaling receptor activity)|go:""GO:0010755""(regulation of plasminogen activation)|go:""GO:0010757""(negative regulation of plasminogen activation)|go:""GO:0014909""(smooth muscle cell migration)|go:""GO:0014910""(regulation of smooth muscle cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031639""(plasminogen activation)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035579""(specific granule membrane)|go:""GO:0038195""(urokinase plasminogen activator signaling pathway)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042730""(fibrinolysis)|go:""GO:0051917""(regulation of fibrinolysis)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061041""(regulation of wound healing)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0097180""(serine protease inhibitor complex)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1905370""(serine-type endopeptidase complex)|go:""GO:2000097""(regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000001(Kringle)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050127|mint:P00749|rcsb pdb:1C5W|rcsb pdb:1C5X|rcsb pdb:1C5Y|rcsb pdb:1C5Z|rcsb pdb:1EJN|rcsb pdb:1F5K|rcsb pdb:1F5L|rcsb pdb:1F92|rcsb pdb:1FV9|rcsb pdb:1GI7|rcsb pdb:1GI8|rcsb pdb:1GI9|rcsb pdb:1GJ7|rcsb pdb:1GJ8|rcsb pdb:1GJ9|rcsb pdb:1GJA|rcsb pdb:1GJB|rcsb pdb:1GJC|rcsb pdb:1GJD|rcsb pdb:1KDU|rcsb pdb:1LMW|rcsb pdb:1O3P|rcsb pdb:1O5A|rcsb pdb:1O5B|rcsb pdb:1O5C|rcsb pdb:1OWD|rcsb pdb:1OWE|rcsb pdb:1OWH|rcsb pdb:1OWI|rcsb pdb:1OWJ|rcsb pdb:1OWK|rcsb pdb:1SC8|rcsb pdb:1SQA|rcsb pdb:1SQO|rcsb pdb:1SQT|rcsb pdb:1U6Q|rcsb pdb:1URK|rcsb pdb:1VJ9|rcsb pdb:1VJA|rcsb pdb:1W0Z|rcsb pdb:1W10|rcsb pdb:1W11|rcsb pdb:1W12|rcsb pdb:1W13|rcsb pdb:1W14|rcsb pdb:2FD6|rcsb pdb:2I9A|rcsb pdb:2I9B|rcsb pdb:2NWN|rcsb pdb:2O8T|rcsb pdb:2O8U|rcsb pdb:2O8W|rcsb pdb:2R2W|rcsb pdb:2VIN|rcsb pdb:2VIO|rcsb pdb:2VIP|rcsb pdb:2VIQ|rcsb pdb:2VIV|rcsb pdb:2VIW|rcsb pdb:2VNT|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3IG6|rcsb pdb:3KGP|rcsb pdb:3KHV|rcsb pdb:3KID|rcsb pdb:3M61|rcsb pdb:3MHW|rcsb pdb:3MWI|rcsb pdb:3OX7|rcsb pdb:3OY5|rcsb pdb:3OY6|rcsb pdb:3PB1|rcsb pdb:3QN7|rcsb pdb:3U73|rcsb pdb:4DVA|rcsb pdb:4DW2|rcsb pdb:4FU7|rcsb pdb:4FU8|rcsb pdb:4FU9|rcsb pdb:4FUB|rcsb pdb:4FUC|rcsb pdb:4FUD|rcsb pdb:4FUE|rcsb pdb:4FUF|rcsb pdb:4FUG|rcsb pdb:4FUH|rcsb pdb:4FUI|rcsb pdb:4FUJ|rcsb pdb:4GLY|rcsb pdb:4H42|rcsb pdb:4JK5|rcsb pdb:4JK6|rcsb pdb:4K24|rcsb pdb:4MNV|rcsb pdb:4MNW|rcsb pdb:4MNX|rcsb pdb:4MNY|rcsb pdb:4OS1|rcsb pdb:4OS2|rcsb pdb:4OS4|rcsb pdb:4OS5|rcsb pdb:4OS6|rcsb pdb:4OS7|rcsb pdb:4X0W|rcsb pdb:4X1N|rcsb pdb:4X1P|rcsb pdb:4X1Q|rcsb pdb:4X1R|rcsb pdb:4X1S|rcsb pdb:4XSK|rcsb pdb:4ZHL|rcsb pdb:4ZHM|rcsb pdb:4ZKN|rcsb pdb:4ZKO|rcsb pdb:4ZKR|rcsb pdb:4ZKS|rcsb pdb:5HGG|rcsb pdb:5WXF|rcsb pdb:5WXO|rcsb pdb:5WXP|rcsb pdb:5WXQ|rcsb pdb:5WXR|rcsb pdb:5WXS|rcsb pdb:5WXT|rcsb pdb:5XG4|rcsb pdb:5YC6|rcsb pdb:5YC7|rcsb pdb:5Z1C|rcsb pdb:5ZA7|rcsb pdb:5ZA8|rcsb pdb:5ZA9|rcsb pdb:5ZAE|rcsb pdb:5ZAF|rcsb pdb:5ZAG|rcsb pdb:5ZAH|rcsb pdb:5ZAJ|rcsb pdb:5ZC5|rcsb pdb:6AG2|rcsb pdb:6AG3|rcsb pdb:6AG7|rcsb pdb:6AG9|rcsb pdb:6JYP|rcsb pdb:6JYQ|rcsb pdb:6L04|rcsb pdb:6L05|rcsb pdb:6NMB|rcsb pdb:6XVD|rcsb pdb:7DZD|rcsb pdb:7VM4|rcsb pdb:7VM5|rcsb pdb:7VM6|rcsb pdb:7VM7|rcsb pdb:7ZRR|rcsb pdb:7ZRT|reactome:R-HSA-6798695|reactome:R-HSA-75205|refseq:NP_001138503.1|refseq:NP_001306120.1|refseq:NP_002649.1|refseq:XP_011538168.1|efo:""Orphanet:220436""|panther:PTHR24264(orthology-group)"	-	-	-	figure legend:6A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2025/01/27	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:umsYUdlqit6f+IIU/2XZ44O3Yos9606	intact-crc:9DFE65EB4F5EA07A|rigid:PSy9/vZhGogv+U+VGJQbD/hKSyU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P0DMV8	uniprotkb:P04958	intact:EBI-11052499|uniprotkb:Q9UQM0|uniprotkb:Q5SP17|uniprotkb:Q5JQI4|uniprotkb:P08107|uniprotkb:B4E3B6|uniprotkb:Q9UQL9|uniprotkb:P19790|ensembl:ENSP00000364802.5|ensembl:ENSP00000382915.1|ensembl:ENSP00000404524.1|ensembl:ENSP00000406359.1|ensembl:ENSP00000408907.1	intact:EBI-13951617	psi-mi:hs71a_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSX70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 1(gene name synonym)|uniprotkb:HSP72(gene name synonym)|uniprotkb:Heat shock protein family A member 1A(gene name synonym)	psi-mi:tetx_clote(display_long)|uniprotkb:tetX(gene name)|psi-mi:tetX(display_short)|uniprotkb:Tentoxylysin(gene name synonym)|uniprotkb:CTC_p60(locus name)	"psi-mi:""MI:0892""(solid phase assay)"	Rohrer et al. (2014)	pubmed:24428437|imex:IM-25707	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:212717(""Clostridium tetani (strain Massachusetts / E88)"")|taxid:212717(""Clostridium tetani (strain Massachusetts / E88)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13951564|imex:IM-25707-1	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005336.3|refseq:NP_005337.2|ensembl:ENSG00000204389.10(gene)|ensembl:ENSG00000215328.6(gene)|ensembl:ENSG00000234475.5(gene)|ensembl:ENSG00000235941.5(gene)|ensembl:ENSG00000237724.5(gene)|ensembl:ENST00000375651.7(transcript)|ensembl:ENST00000400040.1(transcript)|ensembl:ENST00000430065.1(transcript)|ensembl:ENST00000433487.1(transcript)|ensembl:ENST00000441618.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007041""(lysosomal transport)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016234""(inclusion body)|go:""GO:0016235""(aggresome)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031249""(denatured protein binding)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033120""(positive regulation of RNA splicing)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0038177""(death receptor agonist activity)|go:""GO:0042026""(protein refolding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0055131""(C3HC4-type RING finger domain binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070370""(cellular heat acclimation)|go:""GO:0070434""(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0072562""(blood microparticle)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:0090084""(negative regulation of inclusion body assembly)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140416""(transcription regulator inhibitor activity)|go:""GO:0140545""(ATP-dependent protein disaggregase activity)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1901673""(regulation of mitotic spindle assembly)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902380""(positive regulation of endoribonuclease activity)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P0DMV8|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:2LMG|rcsb pdb:3A8Y|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|rcsb pdb:3Q49|rcsb pdb:4IO8|rcsb pdb:4J8F|rcsb pdb:4PO2|rcsb pdb:4WV5|rcsb pdb:4WV7|rcsb pdb:5AQW|rcsb pdb:5AQX|rcsb pdb:5AQY|rcsb pdb:5AQZ|rcsb pdb:5AR0|rcsb pdb:5BN8|rcsb pdb:5BN9|rcsb pdb:5BPL|rcsb pdb:5BPM|rcsb pdb:5BPN|rcsb pdb:5GJJ|rcsb pdb:5MKR|rcsb pdb:5MKS|rcsb pdb:5XI9|rcsb pdb:5XIR|rcsb pdb:6FHK|rcsb pdb:6G3R|rcsb pdb:6G3S|rcsb pdb:6JPV|rcsb pdb:6K39|rcsb pdb:6ZYI|rcsb pdb:7FGM|rcsb pdb:7KW7|rcsb pdb:7Q4R|reactome:R-HSA-168330|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-450408|reactome:R-HSA-6798695|reactome:R-HSA-9833482|reactome:R-HSA-9841251|panther:PTHR19375(orthology-group)"	"rcsb pdb:7OH0|rcsb pdb:7OH1|rcsb pdb:1Z7H|rcsb pdb:3HMY|rcsb pdb:3HN1|rcsb pdb:4J1L|reactome:R-HSA-5250982|rcsb pdb:1DIW|rcsb pdb:1DLL|rcsb pdb:1YYN|refseq:WP_011100836.1|rcsb pdb:1A8D|rcsb pdb:1AF9|rcsb pdb:1D0H|rcsb pdb:1DFQ|rcsb pdb:1FV2|rcsb pdb:1FV3|rcsb pdb:1YVG|rcsb pdb:1YXW|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR012500(Clostridium neurotoxin, translocation)|rcsb pdb:5N0B|rcsb pdb:5N0C|interpro:IPR036248|rcsb pdb:7BXX|rcsb pdb:7BY4|rcsb pdb:7BY5|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0044079""(symbiont-mediated perturbation of host neurotransmitter secretion)|go:""GO:0090729""(toxin activity)"	-	-	-	figure legend:3 A/B, 4|comment:ATP did not inhibit binding of the SBD construct.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2024/11/14	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	rogid:arI9eRMHUPPu5ZWeO5ET1JoJKB0212717	intact-crc:62CAFAF72B53DC52|rigid:nymbssnQLQSb3N8v6GX2/NVnLV8	false	his tag:n-n|mutation decreasing interaction strength:438-438|sufficient binding region:1-541|t7 tag:n-n|mutation decreasing interaction strength:406-406	biotin tag:n-n|sufficient binding region:947-966	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0DMV8	uniprotkb:P04958	intact:EBI-11052499|uniprotkb:Q9UQM0|uniprotkb:Q5SP17|uniprotkb:Q5JQI4|uniprotkb:P08107|uniprotkb:B4E3B6|uniprotkb:Q9UQL9|uniprotkb:P19790|ensembl:ENSP00000364802.5|ensembl:ENSP00000382915.1|ensembl:ENSP00000404524.1|ensembl:ENSP00000406359.1|ensembl:ENSP00000408907.1	intact:EBI-13951617	psi-mi:hs71a_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSX70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 1(gene name synonym)|uniprotkb:HSP72(gene name synonym)|uniprotkb:Heat shock protein family A member 1A(gene name synonym)	psi-mi:tetx_clote(display_long)|uniprotkb:tetX(gene name)|psi-mi:tetX(display_short)|uniprotkb:Tentoxylysin(gene name synonym)|uniprotkb:CTC_p60(locus name)	"psi-mi:""MI:0892""(solid phase assay)"	Rohrer et al. (2014)	pubmed:24428437|imex:IM-25707	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:212717(""Clostridium tetani (strain Massachusetts / E88)"")|taxid:212717(""Clostridium tetani (strain Massachusetts / E88)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13951666|imex:IM-25707-2	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005336.3|refseq:NP_005337.2|ensembl:ENSG00000204389.10(gene)|ensembl:ENSG00000215328.6(gene)|ensembl:ENSG00000234475.5(gene)|ensembl:ENSG00000235941.5(gene)|ensembl:ENSG00000237724.5(gene)|ensembl:ENST00000375651.7(transcript)|ensembl:ENST00000400040.1(transcript)|ensembl:ENST00000430065.1(transcript)|ensembl:ENST00000433487.1(transcript)|ensembl:ENST00000441618.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007041""(lysosomal transport)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016234""(inclusion body)|go:""GO:0016235""(aggresome)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031249""(denatured protein binding)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033120""(positive regulation of RNA splicing)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0038177""(death receptor agonist activity)|go:""GO:0042026""(protein refolding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0055131""(C3HC4-type RING finger domain binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070370""(cellular heat acclimation)|go:""GO:0070434""(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0072562""(blood microparticle)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:0090084""(negative regulation of inclusion body assembly)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140416""(transcription regulator inhibitor activity)|go:""GO:0140545""(ATP-dependent protein disaggregase activity)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1901673""(regulation of mitotic spindle assembly)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902380""(positive regulation of endoribonuclease activity)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P0DMV8|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:2LMG|rcsb pdb:3A8Y|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|rcsb pdb:3Q49|rcsb pdb:4IO8|rcsb pdb:4J8F|rcsb pdb:4PO2|rcsb pdb:4WV5|rcsb pdb:4WV7|rcsb pdb:5AQW|rcsb pdb:5AQX|rcsb pdb:5AQY|rcsb pdb:5AQZ|rcsb pdb:5AR0|rcsb pdb:5BN8|rcsb pdb:5BN9|rcsb pdb:5BPL|rcsb pdb:5BPM|rcsb pdb:5BPN|rcsb pdb:5GJJ|rcsb pdb:5MKR|rcsb pdb:5MKS|rcsb pdb:5XI9|rcsb pdb:5XIR|rcsb pdb:6FHK|rcsb pdb:6G3R|rcsb pdb:6G3S|rcsb pdb:6JPV|rcsb pdb:6K39|rcsb pdb:6ZYI|rcsb pdb:7FGM|rcsb pdb:7KW7|rcsb pdb:7Q4R|reactome:R-HSA-168330|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-450408|reactome:R-HSA-6798695|reactome:R-HSA-9833482|reactome:R-HSA-9841251|panther:PTHR19375(orthology-group)"	"rcsb pdb:7OH0|rcsb pdb:7OH1|rcsb pdb:1Z7H|rcsb pdb:3HMY|rcsb pdb:3HN1|rcsb pdb:4J1L|reactome:R-HSA-5250982|rcsb pdb:1DIW|rcsb pdb:1DLL|rcsb pdb:1YYN|refseq:WP_011100836.1|rcsb pdb:1A8D|rcsb pdb:1AF9|rcsb pdb:1D0H|rcsb pdb:1DFQ|rcsb pdb:1FV2|rcsb pdb:1FV3|rcsb pdb:1YVG|rcsb pdb:1YXW|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR012500(Clostridium neurotoxin, translocation)|rcsb pdb:5N0B|rcsb pdb:5N0C|interpro:IPR036248|rcsb pdb:7BXX|rcsb pdb:7BY4|rcsb pdb:7BY5|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0044079""(symbiont-mediated perturbation of host neurotransmitter secretion)|go:""GO:0090729""(toxin activity)"	-	-	-	figure legend:3Ai|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2024/11/14	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	rogid:arI9eRMHUPPu5ZWeO5ET1JoJKB0212717	intact-crc:5087094EF88B481A	false	his tag:n-n|mutation decreasing interaction strength:438-438|sufficient binding region:1-541|t7 tag:n-n|mutation decreasing interaction strength:406-406	biotin tag:n-n|sufficient binding region:947-966	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0DMV8	uniprotkb:P04958	intact:EBI-11052499|uniprotkb:Q9UQM0|uniprotkb:Q5SP17|uniprotkb:Q5JQI4|uniprotkb:P08107|uniprotkb:B4E3B6|uniprotkb:Q9UQL9|uniprotkb:P19790|ensembl:ENSP00000364802.5|ensembl:ENSP00000382915.1|ensembl:ENSP00000404524.1|ensembl:ENSP00000406359.1|ensembl:ENSP00000408907.1	intact:EBI-13951617	psi-mi:hs71a_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSX70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 1(gene name synonym)|uniprotkb:HSP72(gene name synonym)|uniprotkb:Heat shock protein family A member 1A(gene name synonym)	psi-mi:tetx_clote(display_long)|uniprotkb:tetX(gene name)|psi-mi:tetX(display_short)|uniprotkb:Tentoxylysin(gene name synonym)|uniprotkb:CTC_p60(locus name)	"psi-mi:""MI:0892""(solid phase assay)"	Rohrer et al. (2014)	pubmed:24428437|imex:IM-25707	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:212717(""Clostridium tetani (strain Massachusetts / E88)"")|taxid:212717(""Clostridium tetani (strain Massachusetts / E88)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13951730|imex:IM-25707-4	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005336.3|refseq:NP_005337.2|ensembl:ENSG00000204389.10(gene)|ensembl:ENSG00000215328.6(gene)|ensembl:ENSG00000234475.5(gene)|ensembl:ENSG00000235941.5(gene)|ensembl:ENSG00000237724.5(gene)|ensembl:ENST00000375651.7(transcript)|ensembl:ENST00000400040.1(transcript)|ensembl:ENST00000430065.1(transcript)|ensembl:ENST00000433487.1(transcript)|ensembl:ENST00000441618.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007041""(lysosomal transport)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016234""(inclusion body)|go:""GO:0016235""(aggresome)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031249""(denatured protein binding)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033120""(positive regulation of RNA splicing)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0038177""(death receptor agonist activity)|go:""GO:0042026""(protein refolding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0055131""(C3HC4-type RING finger domain binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070370""(cellular heat acclimation)|go:""GO:0070434""(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0072562""(blood microparticle)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:0090084""(negative regulation of inclusion body assembly)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140416""(transcription regulator inhibitor activity)|go:""GO:0140545""(ATP-dependent protein disaggregase activity)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1901673""(regulation of mitotic spindle assembly)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902380""(positive regulation of endoribonuclease activity)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P0DMV8|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:2LMG|rcsb pdb:3A8Y|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|rcsb pdb:3Q49|rcsb pdb:4IO8|rcsb pdb:4J8F|rcsb pdb:4PO2|rcsb pdb:4WV5|rcsb pdb:4WV7|rcsb pdb:5AQW|rcsb pdb:5AQX|rcsb pdb:5AQY|rcsb pdb:5AQZ|rcsb pdb:5AR0|rcsb pdb:5BN8|rcsb pdb:5BN9|rcsb pdb:5BPL|rcsb pdb:5BPM|rcsb pdb:5BPN|rcsb pdb:5GJJ|rcsb pdb:5MKR|rcsb pdb:5MKS|rcsb pdb:5XI9|rcsb pdb:5XIR|rcsb pdb:6FHK|rcsb pdb:6G3R|rcsb pdb:6G3S|rcsb pdb:6JPV|rcsb pdb:6K39|rcsb pdb:6ZYI|rcsb pdb:7FGM|rcsb pdb:7KW7|rcsb pdb:7Q4R|reactome:R-HSA-168330|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-450408|reactome:R-HSA-6798695|reactome:R-HSA-9833482|reactome:R-HSA-9841251|panther:PTHR19375(orthology-group)"	"rcsb pdb:7OH0|rcsb pdb:7OH1|rcsb pdb:1Z7H|rcsb pdb:3HMY|rcsb pdb:3HN1|rcsb pdb:4J1L|reactome:R-HSA-5250982|rcsb pdb:1DIW|rcsb pdb:1DLL|rcsb pdb:1YYN|refseq:WP_011100836.1|rcsb pdb:1A8D|rcsb pdb:1AF9|rcsb pdb:1D0H|rcsb pdb:1DFQ|rcsb pdb:1FV2|rcsb pdb:1FV3|rcsb pdb:1YVG|rcsb pdb:1YXW|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR012500(Clostridium neurotoxin, translocation)|rcsb pdb:5N0B|rcsb pdb:5N0C|interpro:IPR036248|rcsb pdb:7BXX|rcsb pdb:7BY4|rcsb pdb:7BY5|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0044079""(symbiont-mediated perturbation of host neurotransmitter secretion)|go:""GO:0090729""(toxin activity)"	-	-	-	figure legend:3B, 4|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2024/11/14	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	rogid:arI9eRMHUPPu5ZWeO5ET1JoJKB0212717	intact-crc:97BFA8D5507D8667|rigid:nymbssnQLQSb3N8v6GX2/NVnLV8	false	his tag:?-?|sufficient binding region:386-616|t7 tag:n-n	biotin tag:n-n|sufficient binding region:947-966	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:Q601D1	uniprotkb:P02751	intact:EBI-13948049	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q601d1_mesh2(display_long)|uniprotkb:mhp271(locus name)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Deutscher et al. (2010)	pubmed:20879998|imex:IM-25899	"taxid:295358(""Mycoplasma hyopneumoniae (strain 232)"")|taxid:295358(""Mycoplasma hyopneumoniae (strain 232)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13948046|imex:IM-25899-1	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_011206108.1|go:""GO:0016020""(membrane)|go:""GO:1990473""(ciliary targeting signal binding)|interpro:IPR054789"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:5A-B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/06	2025/03/25	rogid:ab8aNdzzoegEDq49GoyPvyqjL8c295358	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:2B2F56CD283A6231|rigid:sjjroDv9uH0ov593c9GFD0Q8QNU	false	his tag:n-n|sufficient binding region:897-1052	biotin tag:?-?	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q601D1	uniprotkb:P02751	intact:EBI-13948049	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q601d1_mesh2(display_long)|uniprotkb:mhp271(locus name)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Deutscher et al. (2010)	pubmed:20879998|imex:IM-25899	"taxid:295358(""Mycoplasma hyopneumoniae (strain 232)"")|taxid:295358(""Mycoplasma hyopneumoniae (strain 232)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13948148|imex:IM-25899-3	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_011206108.1|go:""GO:0016020""(membrane)|go:""GO:1990473""(ciliary targeting signal binding)|interpro:IPR054789"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:5C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.74x10^-7 ~0.13(molar)	2017/03/06	2025/03/25	rogid:ab8aNdzzoegEDq49GoyPvyqjL8c295358	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:AC8164459568C952|rigid:sjjroDv9uH0ov593c9GFD0Q8QNU	false	his tag:n-n|sufficient binding region:897-1052	-	1	1	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:D2TI15	uniprotkb:C9JL25	intact:EBI-13953700	intact:EBI-13953713|ensembl:ENSP00000414446	psi-mi:d2ti15_citri(display_long)|uniprotkb:espT(gene name)|psi-mi:espT(display_short)|uniprotkb:ROD_40911(locus name)	psi-mi:c9jl25_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953697|imex:IM-26206-23	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_012908046.1|interpro:IPR004959(IpaB/EvcA)	"ensembl:ENSG00000144381(gene)|ensembl:ENST00000426480(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0042026""(protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027413"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:D/CavfrldO5JCa1AYHTTWtQn2VQ637910	rogid:IdnpffFohpH20vv64m+dfHtVt9E9606	intact-crc:9075ACA635046484|rigid:t+sDETissrat9R6yVY4w57gZ1AQ	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TJZ4	uniprotkb:E7EQD7	intact:EBI-13953726	intact:EBI-13953740|ensembl:ENSP00000376186.3	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	psi-mi:e7eqd7_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953732|imex:IM-26206-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_012904700.1|mint:D2TJZ4	"ensembl:ENSG00000075711.21(gene)|ensembl:ENST00000392381.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0043005""(neuron projection)|go:""GO:0070161""(anchoring junction)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015143(L27-1)|interpro:IPR016313(""Membrane-associated guanylate kinase (MAGUK) scaffold protein"")|interpro:IPR019583|interpro:IPR019590|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|interpro:IPR050614"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/06	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:7lCXfZ9crnZhGmcgbD+j6Y/mb0k9606	intact-crc:9DF36CCA1805D79E|rigid:aGUeG4dzZmKNkrkg0iv43Xn2CFw	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TJZ4	uniprotkb:P07195	intact:EBI-13953726	intact:EBI-358748|ensembl:ENSP00000229319.1|ensembl:ENSP00000379386.1	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953732|imex:IM-26206-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_012904700.1|mint:D2TJZ4	"ensembl:ENSG00000111716.14(gene)|ensembl:ENST00000350669.5(transcript)|ensembl:ENST00000396076.5(transcript)|go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0019674""(NAD metabolic process)|go:""GO:0019900""(kinase binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045121""(membrane raft)|go:""GO:0051287""(NAD binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990204""(oxidoreductase complex)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|rcsb pdb:7DBJ|rcsb pdb:7DBK|rcsb pdb:8QDE|reactome:R-HSA-70268|refseq:NP_001167568.1|refseq:NP_001302466.1|refseq:NP_002291.1|efo:""Orphanet:284435""|panther:PTHR43128(orthology-group)"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/06	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606	intact-crc:9DF36CCA1805D79E|rigid:aGUeG4dzZmKNkrkg0iv43Xn2CFw	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TJZ4	intact:EBI-11602285	intact:EBI-13953726	-	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	psi-mi:q5szu1_human(display_short)|psi-mi:EBI-11602285(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953732|imex:IM-26206-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_012904700.1|mint:D2TJZ4	uniprotkb:Q5SZU1(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/06	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:V74bduYOcefOD2aN0RBu+Vxv6cg9606	intact-crc:9DF36CCA1805D79E|rigid:aGUeG4dzZmKNkrkg0iv43Xn2CFw	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TJZ4	uniprotkb:F5H365	intact:EBI-13953726	intact:EBI-11081771|ensembl:ENSP00000445393.2	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	psi-mi:f5h365_human(display_long)|uniprotkb:SEC23A(gene name)|psi-mi:SEC23A(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953732|imex:IM-26206-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_012904700.1|mint:D2TJZ4	"ensembl:ENSG00000100934.15(gene)|ensembl:ENST00000545328.6(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0090114""(COPII-coated vesicle budding)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/06	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:Jo8l51YLWp7dF+E5iIgGj6CXvTQ9606	intact-crc:9DF36CCA1805D79E|rigid:aGUeG4dzZmKNkrkg0iv43Xn2CFw	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TJZ4	uniprotkb:O95487	intact:EBI-13953726	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175.4|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953732|imex:IM-26206-25	intact-miscore:0.55	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_012904700.1|mint:D2TJZ4	"refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802.11(gene)|ensembl:ENST00000265175.5(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008270""(zinc ion binding)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0035909""(aorta morphogenesis)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060463""(lung lobe morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061156""(pulmonary artery morphogenesis)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:0090178""(regulation of establishment of planar polarity involved in neural tube closure)|go:""GO:1901301""(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|interpro:IPR050550|mint:O95487|rcsb pdb:3EH1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-9705671|reactome:R-HSA-983170|panther:PTHR13803(orthology-group)|refseq:NP_001287742.1|refseq:NP_001305014.1|refseq:NP_001305015.1"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/06	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	intact-crc:9DF36CCA1805D79E|rigid:aGUeG4dzZmKNkrkg0iv43Xn2CFw	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TJZ4	uniprotkb:F5GZS6	intact:EBI-13953726	intact:EBI-11513218|ensembl:ENSP00000444236.1	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	psi-mi:f5gzs6_human(display_long)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953732|imex:IM-26206-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_012904700.1|mint:D2TJZ4	"ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000535296.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006865""(amino acid transport)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:F5GZS6"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/06	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:xuthwh1izcV9Oh/sw4QgOXEzcLo9606	intact-crc:9DF36CCA1805D79E|rigid:aGUeG4dzZmKNkrkg0iv43Xn2CFw	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:Q5T4U5	intact:EBI-13953760	intact:EBI-13953778|ensembl:ENSP00000359871.5	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:q5t4u5_human(display_long)|uniprotkb:ACADM(gene name)|psi-mi:ACADM(display_short)|uniprotkb:hCG_22915(orf name)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"refseq:NP_001272972.1|ensembl:ENSG00000117054.15(gene)|ensembl:ENST00000370834.9(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070991""(medium-chain fatty acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|interpro:IPR046373|interpro:IPR050741"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:QKJhurnT9l6eZadocqJddKbrvmg9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:P31327	intact:EBI-13953760	intact:EBI-536811|uniprotkb:O43774|uniprotkb:Q7Z5I5|ensembl:ENSP00000233072.5|ensembl:ENSP00000500537.1|ensembl:ENSP00000501022.1|ensembl:ENSP00000501073.1|uniprotkb:B7Z818|uniprotkb:Q53TL5|uniprotkb:J3KQL0|uniprotkb:Q59HF8	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:cpsm_human(display_long)|uniprotkb:Carbamoyl-phosphate synthetase I(gene name synonym)|uniprotkb:CPS1(gene name)|psi-mi:CPS1(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"ensembl:ENSG00000021826.18(gene)|ensembl:ENST00000233072.10(transcript)|ensembl:ENST00000673510.1(transcript)|ensembl:ENST00000673630.1(transcript)|ensembl:ENST00000673711.1(transcript)|go:""GO:0000050""(urea cycle)|go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0004175""(endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005886""(plasma membrane)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0007494""(midgut development)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010043""(response to zinc ion)|go:""GO:0014075""(response to amine)|go:""GO:0016595""(glutamate binding)|go:""GO:0019240""(citrulline biosynthetic process)|go:""GO:0019433""(triglyceride catabolic process)|go:""GO:0030955""(potassium ion binding)|go:""GO:0032094""(response to food)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036094""(small molecule binding)|go:""GO:0042311""(vasodilation)|go:""GO:0042594""(response to starvation)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0043200""(response to amino acid)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046209""(nitric oxide metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050667""(homocysteine metabolic process)|go:""GO:0055081""(monoatomic anion homeostasis)|go:""GO:0060416""(response to growth hormone)|go:""GO:0070365""(hepatocyte differentiation)|go:""GO:0070409""(carbamoyl phosphate biosynthetic process)|go:""GO:0071242""(cellular response to ammonium ion)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0071377""(cellular response to glucagon stimulus)|go:""GO:0071400""(cellular response to oleic acid)|go:""GO:0071548""(response to dexamethasone)|go:""GO:0072341""(modified amino acid binding)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036914|mint:P31327|rcsb pdb:2YVQ|rcsb pdb:4UTR|rcsb pdb:4UTV|rcsb pdb:4UTX|rcsb pdb:4UTZ|rcsb pdb:4UU7|rcsb pdb:4UU8|rcsb pdb:4UUA|rcsb pdb:4UUB|rcsb pdb:5DOT|rcsb pdb:5DOU|rcsb pdb:5OJO|rcsb pdb:6UEL|rcsb pdb:6W2J|reactome:R-HSA-70635|refseq:NP_001116105.1|refseq:NP_001116106.1|refseq:NP_001866.2|refseq:XP_011508943.1|refseq:XP_011508944.1|refseq:XP_011508945.1|refseq:XP_011508946.1|panther:PTHR11405(orthology-group)|efo:""Orphanet:147"""	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:497s02igPCWuQcU4lVrMpl5SRig9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:E7EUT5	intact:EBI-13953760	intact:EBI-13953808|ensembl:ENSP00000380065.1	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:e7eut5_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"ensembl:ENSG00000111640.15(gene)|ensembl:ENST00000396856.5(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006096""(glycolytic process)|go:""GO:0006417""(regulation of translation)|go:""GO:0006915""(apoptotic process)|go:""GO:0016620""(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|go:""GO:0016740""(transferase activity)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0051287""(NAD binding)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:9NNAye2VlyGd38IKdhtjHQXlPWo9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:P33993	intact:EBI-13953760	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288.5	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"efo:""Orphanet:2512""|ensembl:ENSG00000166508.19(gene)|ensembl:ENST00000303887.10(transcript)|go:""GO:0000727""(double-strand break repair via break-induced replication)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006271""(DNA strand elongation involved in DNA replication)|go:""GO:0006974""(DNA damage response)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030174""(regulation of DNA-templated DNA replication initiation)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042325""(regulation of phosphorylation)|go:""GO:0042555""(MCM complex)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071162""(CMG complex)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:7W1Y|rcsb pdb:7W68|rcsb pdb:8B9D|rcsb pdb:8S09|rcsb pdb:8S0A|rcsb pdb:8S0B|rcsb pdb:8S0D|rcsb pdb:8S0E|rcsb pdb:8S0F|rcsb pdb:8W0E|rcsb pdb:8W0F|rcsb pdb:8W0G|rcsb pdb:8W0I|rcsb pdb:9CAQ|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|dip:DIP-27580N|panther:PTHR11630(orthology-group)"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	intact:EBI-11602285	intact:EBI-13953760	-	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:q5szu1_human(display_short)|psi-mi:EBI-11602285(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	uniprotkb:Q5SZU1(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:V74bduYOcefOD2aN0RBu+Vxv6cg9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:Q504U3	intact:EBI-13953760	intact:EBI-34579565	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:q504u3_human(display_long)|uniprotkb:PKM2(gene name)|psi-mi:PKM2(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR040442|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR036918|interpro:IPR015806(Pyruvate kinase, beta-barrel)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016301""(kinase activity)|go:""GO:0030955""(potassium ion binding)"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:3b4vu+PbXUapml4/MlwweS7Rd5o9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:P78527	intact:EBI-13953760	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420.3	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)|uniprotkb:Ser-473 kinase(gene name synonym)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"efo:""Orphanet:317425""|ensembl:ENSG00000253729.9(gene)|ensembl:ENST00000314191.7(transcript)|go:""GO:0000460""(maturation of 5.8S rRNA)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0001756""(somitogenesis)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0002326""(B cell lineage commitment)|go:""GO:0002327""(immature B cell differentiation)|go:""GO:0002328""(pro-B cell differentiation)|go:""GO:0002360""(T cell lineage commitment)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0016020""(membrane)|go:""GO:0016233""(telomere capping)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0031648""(protein destabilization)|go:""GO:0032040""(small-subunit processome)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033152""(""immunoglobulin V(D)J recombination"")|go:""GO:0033153""(""T cell receptor V(D)J recombination"")|go:""GO:0034462""(small-subunit processome assembly)|go:""GO:0034511""(U3 snoRNA binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035234""(ectopic germ cell programmed cell death)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036211""(protein modification process)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045087""(innate immune response)|go:""GO:0045621""(positive regulation of lymphocyte differentiation)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0050678""(regulation of epithelial cell proliferation)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097681""(double-strand break repair via alternative nonhomologous end joining)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:0160049""(negative regulation of cGAS/STING signaling pathway)|go:""GO:1902036""(regulation of hematopoietic stem cell differentiation)|go:""GO:1905221""(positive regulation of platelet formation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|interpro:IPR045581|interpro:IPR046803|interpro:IPR046804|interpro:IPR050517|mint:P78527|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|rcsb pdb:7K11|rcsb pdb:7K19|rcsb pdb:7K1B|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7OTM|rcsb pdb:7OTP|rcsb pdb:7OTV|rcsb pdb:7OTW|rcsb pdb:7OTY|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7SUD|rcsb pdb:7TYR|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZ9|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|refseq:NP_001075109.1|refseq:NP_008835.5|dip:DIP-24186N|panther:PTHR11139(orthology-group)"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:E9PPV6	intact:EBI-13953760	intact:EBI-13953847|ensembl:ENSP00000436305.1|ensembl:ENSP00000497544.1	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:e9ppv6_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"ensembl:ENSG00000149257.16(gene)|ensembl:ENST00000530284.5(transcript)|ensembl:ENST00000649490.1(transcript)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:mxbMDFNw2OLmQ0pRKmtqiW1QXOE9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:P05141	intact:EBI-13953760	intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671.4	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"refseq:NP_001143.2|ensembl:ENSG00000005022.6(gene)|ensembl:ENST00000317881.9(transcript)|go:""GO:0000295""(adenine nucleotide transmembrane transporter activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005471""(""ATP:ADP antiporter activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005757""(mitochondrial permeability transition pore complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0007059""(chromosome segregation)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0015078""(proton transmembrane transporter activity)|go:""GO:0015207""(adenine transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0017077""(oxidative phosphorylation uncoupler activity)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0046902""(regulation of mitochondrial membrane permeability)|go:""GO:0051503""(adenine nucleotide transport)|go:""GO:0071817""(MMXD complex)|go:""GO:0140021""(mitochondrial ADP transmembrane transport)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1901526""(positive regulation of mitophagy)|go:""GO:1990544""(mitochondrial ATP transmembrane transport)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990845""(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|reactome:R-HSA-180897|reactome:R-HSA-83936|reactome:R-HSA-9837999|dip:DIP-33873N|panther:PTHR45635(orthology-group)"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:P12236	intact:EBI-13953760	intact:EBI-356254|uniprotkb:Q96C49|ensembl:ENSP00000370808.5|ensembl:ENSP00000518609.1	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"refseq:NP_001627.2|ensembl:ENSG00000169100.14(gene)|ensembl:ENSG00000292334.1(gene)|ensembl:ENST00000381401.11(transcript)|ensembl:ENST00000711214.1(transcript)|go:""GO:0005471""(""ATP:ADP antiporter activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005744""(TIM23 mitochondrial import inner membrane translocase complex)|go:""GO:0006915""(apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0140021""(mitochondrial ADP transmembrane transport)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1990544""(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|reactome:R-HSA-9837999|panther:PTHR45635(orthology-group)"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:G3V2A3	intact:EBI-13953760	intact:EBI-13953863|ensembl:ENSP00000450538.1	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:g3v2a3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"ensembl:ENSG00000258947.8(gene)|ensembl:ENST00000555810.5(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005874""(microtubule)|go:""GO:0007017""(microtubule-based process)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030175""(filopodium)|go:""GO:0045171""(intercellular bridge)|go:""GO:0072686""(mitotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR017975|interpro:IPR036525"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:na4M7+7hGMj3FjTSNZPjKmWdNsg9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:P49411	intact:EBI-13953760	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439.3	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"efo:""Orphanet:254925""|ensembl:ENSG00000178952.11(gene)|ensembl:ENST00000313511.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045202""(synapse)|go:""GO:0045471""(response to ethanol)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070125""(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|interpro:IPR050055|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|reactome:R-HSA-9754560|refseq:NP_003312.3|refseq:XP_016879108.1|panther:PTHR43721(orthology-group)"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:gmW0HIoZ+8MccQHJ44Lcu2uwCss9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TK72	uniprotkb:H3BSJ9	intact:EBI-13953760	intact:EBI-13953882|ensembl:ENSP00000456738.1	psi-mi:d2tk72_citri(display_long)|uniprotkb:nleG1(gene name)|psi-mi:nleG1(display_short)|uniprotkb:ROD_16511(locus name)	psi-mi:h3bsj9_human(display_long)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13953770|imex:IM-26206-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012905902.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)"	"ensembl:ENSG00000140740.11(gene)|ensembl:ENST00000563898.5(transcript)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR050361"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/10	rogid:05RN3NwGlPCfk87ta3qbELn2DG0637910	rogid:z6v0MFRvW5DNlbH8Jd+/7csdxhY9606	intact-crc:3954FAEDFDDB1A30|rigid:KUkcj6RrO9ZTxqZvZ9cte4kVpdE	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TRA0	uniprotkb:M0QZM1	intact:EBI-16463706	intact:EBI-16463720|ensembl:ENSP00000470635.1	psi-mi:d2tra0_citri(display_long)|uniprotkb:ROD_09131(locus name)	psi-mi:m0qzm1_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-16463712|imex:IM-26206-11	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_012905236.1|interpro:IPR019289	"ensembl:ENSG00000099783.13(gene)|ensembl:ENST00000597270.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR050374"	-	-	-	figure legend:figure 2 and table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:Y19ezvgqvfARjvY4I0o6jv9wgiM637910	rogid:zoLEWyuF3tfeP/lPcMDGExrSD3s9606	intact-crc:DB2A1FD16C8FBB32|rigid:MEUrO6Azx0GgHfeGLhv8MOC76tA	false	his tag:n-n|sbp:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D2TRA0	uniprotkb:M0QZM1	intact:EBI-16463706	intact:EBI-16463720|ensembl:ENSP00000470635.1	psi-mi:d2tra0_citri(display_long)|uniprotkb:ROD_09131(locus name)	psi-mi:m0qzm1_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Sontag et al. (2015)	pubmed:27822540|imex:IM-26206	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-16463844|imex:IM-26206-19	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_012905236.1|interpro:IPR019289	"ensembl:ENSG00000099783.13(gene)|ensembl:ENST00000597270.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR050374"	-	-	-	figure legend:2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:Y19ezvgqvfARjvY4I0o6jv9wgiM637910	rogid:zoLEWyuF3tfeP/lPcMDGExrSD3s9606	intact-crc:966AFF47EB0A4F5C|rigid:MEUrO6Azx0GgHfeGLhv8MOC76tA	false	his tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q7DB76	uniprotkb:Q15599	intact:EBI-10039068|uniprotkb:Q7A9Q0|uniprotkb:A0A0H3JJD5|uniprotkb:A0A6M0JL37	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	psi-mi:q7db76_eco57(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:ECs_4562(orf name)	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947909|imex:IM-25986-1	intact-miscore:0.57	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000492638.1|interpro:IPR004959(IpaB/EvcA)|refseq:NP_312589.1	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:xO5ymWP2ug1VLyxelIaeen+24gM83334	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	intact-crc:3075C103F6319A30|rigid:ZFQ2ER4vDnTY3j2m0nmj7IjFPoQ	false	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q8XB62	uniprotkb:Q8TEB1	intact:EBI-10038787|uniprotkb:Q7ACX7|uniprotkb:A0A0H3JG75|uniprotkb:A0A6M0JSQ6	intact:EBI-2213388|ensembl:ENSP00000415556.4|ensembl:ENSP00000452898.1|ensembl:ENSP00000494282.1|ensembl:ENSP00000495416.1|uniprotkb:Q5D039|uniprotkb:Q86U00|uniprotkb:Q86U39|uniprotkb:Q8NDN2|uniprotkb:Q9H2J0|uniprotkb:Q9H3A3|uniprotkb:Q9H5C9|uniprotkb:D3DS56|uniprotkb:B3KQ83	psi-mi:q8xb62_eco57(display_long)|uniprotkb:espJ(gene name)|psi-mi:espJ(display_short)|uniprotkb:ECs_2714(orf name)	psi-mi:dca11_human(display_long)|uniprotkb:DCAF11(gene name)|psi-mi:DCAF11(display_short)|uniprotkb:GL014(orf name)|uniprotkb:PRO2389(orf name)|uniprotkb:WDR23(gene name synonym)|uniprotkb:WD repeat-containing protein 23(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947939|imex:IM-25986-3	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000022458.1|interpro:IPR015226(AvrPphF ORF-2)|refseq:NP_310741.1	"ensembl:ENSG00000100897.18(gene)|ensembl:ENSG00000284796.3(gene)|interpro:IPR015943(WD40/YVTN repeat-like)|ensembl:ENST00000446197.8(transcript)|ensembl:ENST00000559115.5(transcript)|ensembl:ENST00000642239.1(transcript)|ensembl:ENST00000646568.3(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR017399(WD repeat protein 23)|interpro:IPR020472|interpro:IPR036322|interpro:IPR051859|mint:Q8TEB1|reactome:R-HSA-8951664|refseq:NP_001156956.1|refseq:NP_079506.3|refseq:NP_852002.1|panther:PTHR19847(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:pwnhf6VxgSKHIqJxvoUGpqp7Iu083334	rogid:iQQ4lP7NSE1MIcskh1XBjj9CC0s9606	intact-crc:D9CCC63E677357D7|rigid:/A3Tu+/EtixOKni/9VltmsqdPAg	false	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3JP21	uniprotkb:Q14244	intact:EBI-13951059|uniprotkb:A0A6M0JH29	intact:EBI-2211064|ensembl:ENSP00000346581.2|uniprotkb:Q7Z6S0|uniprotkb:Q8TAU5|uniprotkb:Q9NY82|uniprotkb:Q9NY83|uniprotkb:B7Z290|uniprotkb:B7Z9U7|uniprotkb:C9JPS0|uniprotkb:F5H1E2|uniprotkb:B7Z400|uniprotkb:B7Z5S7|uniprotkb:E9PCP3	psi-mi:a0a0h3jp21_eco57(display_long)|uniprotkb:espL2(gene name)|psi-mi:espL2(display_short)|uniprotkb:ECs_3855(orf name)	psi-mi:map7_human(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947943|imex:IM-25986-5	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_311882.1|refseq:WP_001121626.1|interpro:IPR012927(ShET2 enterotoxin, N-terminal)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)"	"ensembl:ENSG00000135525.19(gene)|ensembl:ENST00000354570.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR008604(E-MAP-115)|interpro:IPR051483|mint:Q14244|rcsb pdb:7SGS|refseq:NP_001185537.1|refseq:NP_001185543.1|refseq:NP_001185544.1|refseq:NP_001185545.1|refseq:NP_001185546.1|refseq:NP_001185547.1|refseq:NP_003971.1|refseq:NP_001185538.1|refseq:NP_001185540.1|refseq:NP_001185548.1|refseq:XP_006715663.1|refseq:XP_016866960.1|panther:PTHR15073(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:diGPLbHN0f0BhE/UI02PI7WviEw83334	rogid:2BB4pZbXcipOIHXEqAUpq3mEuw49606	intact-crc:426D2B27037872B3|rigid:bjPiBnMoipjI69G1Oz87ODF8Zag	false	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q8XAJ5	uniprotkb:Q15436	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	intact:EBI-81088|uniprotkb:B2R5P4|uniprotkb:Q8NE16|ensembl:ENSP00000306881.6|uniprotkb:B3KXI2	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	psi-mi:sc23a_human(display_long)|uniprotkb:SEC23A(gene name)|psi-mi:SEC23A(display_short)|uniprotkb:SEC23-related protein A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947951|imex:IM-25986-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001025672.1|refseq:NP_309839.1	"ensembl:ENSG00000100934.15(gene)|ensembl:ENST00000307712.11(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008270""(zinc ion binding)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15436|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:2YRC|rcsb pdb:2YRD|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|rcsb pdb:5VNE|rcsb pdb:5VNF|rcsb pdb:5VNG|rcsb pdb:5VNH|rcsb pdb:5VNI|rcsb pdb:5VNJ|rcsb pdb:5VNK|rcsb pdb:5VNL|rcsb pdb:5VNM|rcsb pdb:5VNN|rcsb pdb:5VNO|rcsb pdb:8HR0|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_006355.2|panther:PTHR11141(orthology-group)|efo:""Orphanet:50814"""	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/05	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	rogid:u1FCes02jPb3CGRj1aDkzpbSiuI9606	intact-crc:B3E945D30E9DBEE9|rigid:4/SxEmgr17RBJl0E5KBkro3Ex44	false	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q8XAJ5	uniprotkb:O95487	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175.4|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947951|imex:IM-25986-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001025672.1|refseq:NP_309839.1	"refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802.11(gene)|ensembl:ENST00000265175.5(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008270""(zinc ion binding)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0035909""(aorta morphogenesis)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060463""(lung lobe morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061156""(pulmonary artery morphogenesis)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:0090178""(regulation of establishment of planar polarity involved in neural tube closure)|go:""GO:1901301""(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|interpro:IPR050550|mint:O95487|rcsb pdb:3EH1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-9705671|reactome:R-HSA-983170|panther:PTHR13803(orthology-group)|refseq:NP_001287742.1|refseq:NP_001305014.1|refseq:NP_001305015.1"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/05	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	intact-crc:B3E945D30E9DBEE9|rigid:4/SxEmgr17RBJl0E5KBkro3Ex44	false	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q8XAJ5	uniprotkb:Q12959	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	intact:EBI-357481|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21|ensembl:ENSP00000391732.2|ensembl:ENSP00000407531.1|ensembl:ENSP00000499437.1	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947951|imex:IM-25986-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001025672.1|refseq:NP_309839.1	"efo:""Orphanet:199306""|ensembl:ENSG00000075711.21(gene)|ensembl:ENST00000419354.5(transcript)|ensembl:ENST00000448528.6(transcript)|ensembl:ENST00000670935.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001658""(branching involved in ureteric bud morphogenesis)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0001772""(immunological synapse)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0002088""(lens development in camera-type eye)|go:""GO:0004385""(guanylate kinase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0005604""(basement membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007399""(nervous system development)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0014704""(intercalated disc)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030054""(cell junction)|go:""GO:0030432""(peristalsis)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031253""(cell projection membrane)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0031579""(membrane raft organization)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031641""(regulation of myelination)|go:""GO:0033268""(node of Ranvier)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042383""(sarcolemma)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042982""(amyloid precursor protein metabolic process)|go:""GO:0043005""(neuron projection)|go:""GO:0043113""(receptor clustering)|go:""GO:0043219""(lateral loop)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048608""(reproductive structure development)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0048745""(smooth muscle tissue development)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0051660""(establishment of centrosome localization)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060022""(hard palate development)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0097016""(L27 domain binding)|go:""GO:0097025""(MPP7-DLG1-LIN7 complex)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097120""(receptor localization to synapse)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0098915""(membrane repolarization during ventricular cardiac muscle cell action potential)|go:""GO:0098919""(structural constituent of postsynaptic density)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099645""(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:1902305""(regulation of sodium ion transmembrane transport)|go:""GO:1902473""(regulation of protein localization to synapse)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903286""(regulation of potassium ion import)|go:""GO:1903753""(negative regulation of p38MAPK cascade)|go:""GO:1903764""(regulation of potassium ion export across plasma membrane)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313(""Membrane-associated guanylate kinase (MAGUK) scaffold protein"")|interpro:IPR019583|interpro:IPR036034|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036892|interpro:IPR050614|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|rcsb pdb:7PC3|rcsb pdb:8CN1|rcsb pdb:8CN3|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_001277912.1|refseq:NP_004078.2|refseq:XP_005269346.1|refseq:XP_011510804.1|refseq:XP_011510805.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861299.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|panther:PTHR23119(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/03/05	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606	intact-crc:B3E945D30E9DBEE9|rigid:4/SxEmgr17RBJl0E5KBkro3Ex44	false	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q8X834	uniprotkb:Q09472	intact:EBI-10039193|uniprotkb:A0A7U8R4U9|uniprotkb:Q7AGE2|uniprotkb:A0A6M0JJK4|uniprotkb:A0A6M6W2Q6	intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|ensembl:ENSP00000263253.7|ensembl:ENSP00000520505.1|intact:EBI-28987257	psi-mi:q8x834_eco57(display_long)|uniprotkb:nleC(gene name)|psi-mi:nleC(display_short)|uniprotkb:ECs_0847(orf name)	psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947957|imex:IM-25986-9	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025208|go:""GO:0046872""(metal ion binding)|rcsb pdb:4LGI|rcsb pdb:4LGJ|mint:Q8X834|refseq:NP_308874.1"	"ensembl:ENSG00000100393.16(gene)|ensembl:ENST00000263253.9(transcript)|ensembl:ENST00000715703.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0000785""(chromatin)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001756""(somitogenesis)|go:""GO:0001966""(thigmotaxis)|go:""GO:0002039""(p53 binding)|go:""GO:0002209""(behavioral defense response)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0004468""(L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006110""(regulation of glycolytic process)|go:""GO:0006473""(protein acetylation)|go:""GO:0006475""(internal protein amino acid acetylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007611""(learning or memory)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010484""(histone H3 acetyltransferase activity)|go:""GO:0010485""(histone H4 acetyltransferase activity)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016407""(acetyltransferase activity)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0018076""(N-terminal peptidyl-lysine acetylation)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0018394""(peptidyl-lysine acetylation)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030324""(lung development)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034212""(protein N-acetyltransferase activity)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0036268""(swimming)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0043627""(response to estrogen)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044013""(histone H2B acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045721""(negative regulation of gluconeogenesis)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060765""(regulation of androgen receptor signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061733""(protein-lysine-acetyltransferase activity)|go:""GO:0061920""(protein propionyltransferase activity)|go:""GO:0061921""(peptidyl-lysine propionylation)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:0090043""(regulation of tubulin deacetylation)|go:""GO:0097157""(pre-mRNA intronic binding)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0106226""(peptide 2-hydroxyisobutyryltransferase activity)|go:""GO:0120301""(""histone lactyltransferase (CoA-dependent) activity"")|go:""GO:0140033""(acetylation-dependent protein binding)|go:""GO:0140065""(peptide butyryltransferase activity)|go:""GO:0140066""(peptidyl-lysine crotonylation)|go:""GO:0140067""(peptidyl-lysine butyrylation)|go:""GO:0140068""(histone crotonyltransferase activity)|go:""GO:0140069""(histone butyryltransferase activity)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:0141002""(histone H4K16 propionyltransferase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1904515""(positive regulation of TORC2 signaling)|go:""GO:2000330""(positive regulation of T-helper 17 cell lineage commitment)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4BHW|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|rcsb pdb:7QGS|rcsb pdb:7SS8|rcsb pdb:7SSK|rcsb pdb:7SZQ|rcsb pdb:7UGI|rcsb pdb:7VHY|rcsb pdb:7VHZ|rcsb pdb:7VI0|rcsb pdb:7W9V|rcsb pdb:7XEZ|rcsb pdb:7XFG|rcsb pdb:8E1D|rcsb pdb:8FVF|rcsb pdb:8GZC|rcsb pdb:8HAG|rcsb pdb:8HAH|rcsb pdb:8HAI|rcsb pdb:8HAJ|rcsb pdb:8HAK|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9701898|reactome:R-HSA-9707616|reactome:R-HSA-9735871|reactome:R-HSA-9759194|reactome:R-HSA-9793380|reactome:R-HSA-9818026|reactome:R-HSA-9818027|reactome:R-HSA-9818028|reactome:R-HSA-9818030|reactome:R-HSA-9818032|reactome:R-HSA-9818035|reactome:R-HSA-9818749|reactome:R-HSA-9819196|reactome:R-HSA-9833109|reactome:R-HSA-9839394|reactome:R-HSA-9841922|refseq:NP_001420.2|efo:""Orphanet:353284""|dip:DIP-257N|panther:PTHR13808(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/01/24	rogid:2YRFou+gcur7JjPuYwcTJn7Rrpo83334	rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606	intact-crc:069238872F514FA8|rigid:WGTRFRwebsW2zeIOE7mBZdyJV+U	false	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q8XBX8	uniprotkb:Q14244	intact:EBI-10039153|uniprotkb:Q7AAV0|uniprotkb:A0A0H3JHS6|uniprotkb:A0A6M0JF43	intact:EBI-2211064|ensembl:ENSP00000346581.2|uniprotkb:Q7Z6S0|uniprotkb:Q8TAU5|uniprotkb:Q9NY82|uniprotkb:Q9NY83|uniprotkb:B7Z290|uniprotkb:B7Z9U7|uniprotkb:C9JPS0|uniprotkb:F5H1E2|uniprotkb:B7Z400|uniprotkb:B7Z5S7|uniprotkb:E9PCP3	psi-mi:nleb1_eco57(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:ECs3857(locus name)	psi-mi:map7_human(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947961|imex:IM-25986-21	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000953022.1|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|refseq:NP_311884.1"	"ensembl:ENSG00000135525.19(gene)|ensembl:ENST00000354570.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR008604(E-MAP-115)|interpro:IPR051483|mint:Q14244|rcsb pdb:7SGS|refseq:NP_001185537.1|refseq:NP_001185543.1|refseq:NP_001185544.1|refseq:NP_001185545.1|refseq:NP_001185546.1|refseq:NP_001185547.1|refseq:NP_003971.1|refseq:NP_001185538.1|refseq:NP_001185540.1|refseq:NP_001185548.1|refseq:XP_006715663.1|refseq:XP_016866960.1|panther:PTHR15073(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:s08ivrjNoMdHHNcIwH+V7ZobNOQ83334	rogid:2BB4pZbXcipOIHXEqAUpq3mEuw49606	intact-crc:C2293887C77FE9EF|rigid:KvgOxLQ9mQTzi80op6wTiHb5TJU	false	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q14244	uniprotkb:Q8XBX8	intact:EBI-2211064|ensembl:ENSP00000346581.2|uniprotkb:Q7Z6S0|uniprotkb:Q8TAU5|uniprotkb:Q9NY82|uniprotkb:Q9NY83|uniprotkb:B7Z290|uniprotkb:B7Z9U7|uniprotkb:C9JPS0|uniprotkb:F5H1E2|uniprotkb:B7Z400|uniprotkb:B7Z5S7|uniprotkb:E9PCP3	intact:EBI-10039153|uniprotkb:Q7AAV0|uniprotkb:A0A0H3JHS6|uniprotkb:A0A6M0JF43	psi-mi:map7_human(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)	psi-mi:nleb1_eco57(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:ECs3857(locus name)	"psi-mi:""MI:0019""(coimmunoprecipitation)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947972|imex:IM-25986-11	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000135525.19(gene)|ensembl:ENST00000354570.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR008604(E-MAP-115)|interpro:IPR051483|mint:Q14244|rcsb pdb:7SGS|refseq:NP_001185537.1|refseq:NP_001185543.1|refseq:NP_001185544.1|refseq:NP_001185545.1|refseq:NP_001185546.1|refseq:NP_001185547.1|refseq:NP_003971.1|refseq:NP_001185538.1|refseq:NP_001185540.1|refseq:NP_001185548.1|refseq:XP_006715663.1|refseq:XP_016866960.1|panther:PTHR15073(orthology-group)"	"refseq:WP_000953022.1|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|refseq:NP_311884.1"	-	-	-	figure legend:1B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:2BB4pZbXcipOIHXEqAUpq3mEuw49606	rogid:s08ivrjNoMdHHNcIwH+V7ZobNOQ83334	intact-crc:E5435591770DFA61|rigid:KvgOxLQ9mQTzi80op6wTiHb5TJU	false	-	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3JP21	uniprotkb:Q14244	intact:EBI-13951059|uniprotkb:A0A6M0JH29	intact:EBI-2211064|ensembl:ENSP00000346581.2|uniprotkb:Q7Z6S0|uniprotkb:Q8TAU5|uniprotkb:Q9NY82|uniprotkb:Q9NY83|uniprotkb:B7Z290|uniprotkb:B7Z9U7|uniprotkb:C9JPS0|uniprotkb:F5H1E2|uniprotkb:B7Z400|uniprotkb:B7Z5S7|uniprotkb:E9PCP3	psi-mi:a0a0h3jp21_eco57(display_long)|uniprotkb:espL2(gene name)|psi-mi:espL2(display_short)|uniprotkb:ECs_3855(orf name)	psi-mi:map7_human(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)	"psi-mi:""MI:0019""(coimmunoprecipitation)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947987|imex:IM-25986-13	intact-miscore:0.58	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_311882.1|refseq:WP_001121626.1|interpro:IPR012927(ShET2 enterotoxin, N-terminal)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)"	"ensembl:ENSG00000135525.19(gene)|ensembl:ENST00000354570.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR008604(E-MAP-115)|interpro:IPR051483|mint:Q14244|rcsb pdb:7SGS|refseq:NP_001185537.1|refseq:NP_001185543.1|refseq:NP_001185544.1|refseq:NP_001185545.1|refseq:NP_001185546.1|refseq:NP_001185547.1|refseq:NP_003971.1|refseq:NP_001185538.1|refseq:NP_001185540.1|refseq:NP_001185548.1|refseq:XP_006715663.1|refseq:XP_016866960.1|panther:PTHR15073(orthology-group)"	-	-	-	figure legend:1 C-D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/02/28	rogid:diGPLbHN0f0BhE/UI02PI7WviEw83334	rogid:2BB4pZbXcipOIHXEqAUpq3mEuw49606	intact-crc:DC2DE4D5D814C799|rigid:G9W8tI2EexNuz0WTv06KqRFxZQE	false	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3JP21	uniprotkb:P26641	intact:EBI-13951059|uniprotkb:A0A6M0JH29	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901.4	psi-mi:a0a0h3jp21_eco57(display_long)|uniprotkb:espL2(gene name)|psi-mi:espL2(display_short)|uniprotkb:ECs_3855(orf name)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	"psi-mi:""MI:0019""(coimmunoprecipitation)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947987|imex:IM-25986-13	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_311882.1|refseq:WP_001121626.1|interpro:IPR012927(ShET2 enterotoxin, N-terminal)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)"	"refseq:NP_001395.1|ensembl:ENSG00000254772.10(gene)|ensembl:ENST00000329251.5(transcript)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006414""(translational elongation)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|interpro:IPR050802|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|reactome:R-HSA-9725370|dip:DIP-32516N|panther:PTHR43986(orthology-group)"	-	-	-	figure legend:1 C-D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2025/02/28	rogid:diGPLbHN0f0BhE/UI02PI7WviEw83334	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:DC2DE4D5D814C799|rigid:G9W8tI2EexNuz0WTv06KqRFxZQE	false	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q14244	uniprotkb:A0A0H3JP21	intact:EBI-2211064|ensembl:ENSP00000346581.2|uniprotkb:Q7Z6S0|uniprotkb:Q8TAU5|uniprotkb:Q9NY82|uniprotkb:Q9NY83|uniprotkb:B7Z290|uniprotkb:B7Z9U7|uniprotkb:C9JPS0|uniprotkb:F5H1E2|uniprotkb:B7Z400|uniprotkb:B7Z5S7|uniprotkb:E9PCP3	intact:EBI-13951059|uniprotkb:A0A6M0JH29	psi-mi:map7_human(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)	psi-mi:a0a0h3jp21_eco57(display_long)|uniprotkb:espL2(gene name)|psi-mi:espL2(display_short)|uniprotkb:ECs_3855(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13948001|imex:IM-25986-15	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000135525.19(gene)|ensembl:ENST00000354570.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR008604(E-MAP-115)|interpro:IPR051483|mint:Q14244|rcsb pdb:7SGS|refseq:NP_001185537.1|refseq:NP_001185543.1|refseq:NP_001185544.1|refseq:NP_001185545.1|refseq:NP_001185546.1|refseq:NP_001185547.1|refseq:NP_003971.1|refseq:NP_001185538.1|refseq:NP_001185540.1|refseq:NP_001185548.1|refseq:XP_006715663.1|refseq:XP_016866960.1|panther:PTHR15073(orthology-group)"	"refseq:NP_311882.1|refseq:WP_001121626.1|interpro:IPR012927(ShET2 enterotoxin, N-terminal)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)"	-	-	-	figure legend:2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:2BB4pZbXcipOIHXEqAUpq3mEuw49606	rogid:diGPLbHN0f0BhE/UI02PI7WviEw83334	intact-crc:9CADFDB041CED759|rigid:bjPiBnMoipjI69G1Oz87ODF8Zag	false	flag tag:?-?	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q14244	uniprotkb:Q8XBX8	intact:EBI-2211064|ensembl:ENSP00000346581.2|uniprotkb:Q7Z6S0|uniprotkb:Q8TAU5|uniprotkb:Q9NY82|uniprotkb:Q9NY83|uniprotkb:B7Z290|uniprotkb:B7Z9U7|uniprotkb:C9JPS0|uniprotkb:F5H1E2|uniprotkb:B7Z400|uniprotkb:B7Z5S7|uniprotkb:E9PCP3	intact:EBI-10039153|uniprotkb:Q7AAV0|uniprotkb:A0A0H3JHS6|uniprotkb:A0A6M0JF43	psi-mi:map7_human(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)	psi-mi:nleb1_eco57(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:ECs3857(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13947997|imex:IM-25986-23	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000135525.19(gene)|ensembl:ENST00000354570.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR008604(E-MAP-115)|interpro:IPR051483|mint:Q14244|rcsb pdb:7SGS|refseq:NP_001185537.1|refseq:NP_001185543.1|refseq:NP_001185544.1|refseq:NP_001185545.1|refseq:NP_001185546.1|refseq:NP_001185547.1|refseq:NP_003971.1|refseq:NP_001185538.1|refseq:NP_001185540.1|refseq:NP_001185548.1|refseq:XP_006715663.1|refseq:XP_016866960.1|panther:PTHR15073(orthology-group)"	"refseq:WP_000953022.1|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|refseq:NP_311884.1"	-	-	-	figure legend:2A and 3B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:2BB4pZbXcipOIHXEqAUpq3mEuw49606	rogid:s08ivrjNoMdHHNcIwH+V7ZobNOQ83334	intact-crc:52FE54DDB5D6F1EE|rigid:KvgOxLQ9mQTzi80op6wTiHb5TJU	false	flag tag:?-?|sufficient binding region:1-349	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q14244	uniprotkb:Q8XBX8	intact:EBI-2211064|ensembl:ENSP00000346581.2|uniprotkb:Q7Z6S0|uniprotkb:Q8TAU5|uniprotkb:Q9NY82|uniprotkb:Q9NY83|uniprotkb:B7Z290|uniprotkb:B7Z9U7|uniprotkb:C9JPS0|uniprotkb:F5H1E2|uniprotkb:B7Z400|uniprotkb:B7Z5S7|uniprotkb:E9PCP3	intact:EBI-10039153|uniprotkb:Q7AAV0|uniprotkb:A0A0H3JHS6|uniprotkb:A0A6M0JF43	psi-mi:map7_human(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)	psi-mi:nleb1_eco57(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:ECs3857(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13948014|imex:IM-25986-17	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000135525.19(gene)|ensembl:ENST00000354570.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR008604(E-MAP-115)|interpro:IPR051483|mint:Q14244|rcsb pdb:7SGS|refseq:NP_001185537.1|refseq:NP_001185543.1|refseq:NP_001185544.1|refseq:NP_001185545.1|refseq:NP_001185546.1|refseq:NP_001185547.1|refseq:NP_003971.1|refseq:NP_001185538.1|refseq:NP_001185540.1|refseq:NP_001185548.1|refseq:XP_006715663.1|refseq:XP_016866960.1|panther:PTHR15073(orthology-group)"	"refseq:WP_000953022.1|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|refseq:NP_311884.1"	-	-	-	figure legend:2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:2BB4pZbXcipOIHXEqAUpq3mEuw49606	rogid:s08ivrjNoMdHHNcIwH+V7ZobNOQ83334	intact-crc:17F614EC297A4495|rigid:KvgOxLQ9mQTzi80op6wTiHb5TJU	false	flag tag:?-?	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q14244	uniprotkb:A0A0H3JP21	intact:EBI-2211064|ensembl:ENSP00000346581.2|uniprotkb:Q7Z6S0|uniprotkb:Q8TAU5|uniprotkb:Q9NY82|uniprotkb:Q9NY83|uniprotkb:B7Z290|uniprotkb:B7Z9U7|uniprotkb:C9JPS0|uniprotkb:F5H1E2|uniprotkb:B7Z400|uniprotkb:B7Z5S7|uniprotkb:E9PCP3	intact:EBI-13951059|uniprotkb:A0A6M0JH29	psi-mi:map7_human(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym)	psi-mi:a0a0h3jp21_eco57(display_long)|uniprotkb:espL2(gene name)|psi-mi:espL2(display_short)|uniprotkb:ECs_3855(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Law et al. (2016)	pubmed:27018634|imex:IM-25986	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13948028|imex:IM-25986-19	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000135525.19(gene)|ensembl:ENST00000354570.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR008604(E-MAP-115)|interpro:IPR051483|mint:Q14244|rcsb pdb:7SGS|refseq:NP_001185537.1|refseq:NP_001185543.1|refseq:NP_001185544.1|refseq:NP_001185545.1|refseq:NP_001185546.1|refseq:NP_001185547.1|refseq:NP_003971.1|refseq:NP_001185538.1|refseq:NP_001185540.1|refseq:NP_001185548.1|refseq:XP_006715663.1|refseq:XP_016866960.1|panther:PTHR15073(orthology-group)"	"refseq:NP_311882.1|refseq:WP_001121626.1|interpro:IPR012927(ShET2 enterotoxin, N-terminal)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)"	-	-	-	figure legend:2B and 3C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/08	2024/11/14	rogid:2BB4pZbXcipOIHXEqAUpq3mEuw49606	rogid:diGPLbHN0f0BhE/UI02PI7WviEw83334	intact-crc:31B0FCC7FC45E7E7|rigid:bjPiBnMoipjI69G1Oz87ODF8Zag	false	flag tag:?-?|sufficient binding region:1-349	glutathione s tranferase tag:n-n|ha tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0G4PYZ0	uniprotkb:P0A6Y8	intact:EBI-25339717	intact:EBI-542092|uniprotkb:P04475	psi-mi:a0a0g4pyz0_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952081|imex:IM-25683-1	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	-	no-uniprot-update:	-	figure legend:1A, 3|comment:HLA-DRB1*0801 allele|comment:The DRB1*0402 peptide did not inhibit binding, but all other peptides tested did.|antagonist:low pH|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:45.6x10^-6(molar)	2017/03/20	2024/11/14	rogid:2b6WKV5vcA/AaS5iDadYN7Pfcl49606	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	intact-crc:5B729AB8CDDC8B74|rigid:70m8ITc/UxKiPAoi1bwg+EQ3F6M	false	sufficient binding region:94-106|biotin tag:?-?	-	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A0G4PYZ0	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339717	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a0g4pyz0_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952179|imex:IM-25683-2	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:1B-1|comment:""\""HLA-DRB1*0801 allele  Inhibitor:HLA-DRB1*0901/DRB1*090102 allele (0901 sequence  shown to contain errors and be identical to DRB1*09:01:02 (December 1996)).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:2b6WKV5vcA/AaS5iDadYN7Pfcl49606	intact-crc:804F4DA7D45A8B94|rigid:hLQP/nfaWD02igf7CT66ddwcu+I	false	-	sufficient binding region:94-106|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:Q0R326	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339756	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:q0r326_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)|uniprotkb:HLA-DRB5(gene name synonym)|uniprotkb:hCG_1998957(orf name)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952179|imex:IM-25683-2	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|go:""GO:0016021""|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)"	-	-	no-uniprot-update:	"figure legend:1B-1|comment:""\""HLA-DRB1*0801 allele  Inhibitor:HLA-DRB1*0901/DRB1*090102 allele (0901 sequence  shown to contain errors and be identical to DRB1*09:01:02 (December 1996)).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:Gq4S+WP70PV3KhQds27aWYtFaB09606	intact-crc:804F4DA7D45A8B94|rigid:hLQP/nfaWD02igf7CT66ddwcu+I	false	-	sufficient binding region:94-106	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A0G4PYZ0	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339717	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a0g4pyz0_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952269|imex:IM-25683-3	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:1B-2|comment:""\""HLA-DRB1*0801 allele  Inhibitor: HLA-DRB1*0403\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:2b6WKV5vcA/AaS5iDadYN7Pfcl49606	intact-crc:8B4BC52B73914A93|rigid:n8xaDXBFMDvl5rFgPgPLTz0dVjM	false	-	sufficient binding region:94-106|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A1V1IGJ9	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339774	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a1v1igj9_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952269|imex:IM-25683-3	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:1B-2|comment:""\""HLA-DRB1*0801 allele  Inhibitor: HLA-DRB1*0403\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:t0oiEebDmTMAhQ97YLbgIkwvFek9606	intact-crc:8B4BC52B73914A93|rigid:n8xaDXBFMDvl5rFgPgPLTz0dVjM	false	-	sufficient binding region:94-106|mutation:103-103,100-100	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A0G4PYZ0	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339717	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a0g4pyz0_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952290|imex:IM-25683-4	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:1B-3|comment:""\""HLA-DRB1*0801 allele  Inhibitor: HLA-DRB1*0401\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:2b6WKV5vcA/AaS5iDadYN7Pfcl49606	intact-crc:7A855A0F16DCC4EC|rigid:n8xaDXBFMDvl5rFgPgPLTz0dVjM	false	-	sufficient binding region:94-106|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A1V1IGJ9	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339774	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a1v1igj9_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952290|imex:IM-25683-4	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:1B-3|comment:""\""HLA-DRB1*0801 allele  Inhibitor: HLA-DRB1*0401\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:t0oiEebDmTMAhQ97YLbgIkwvFek9606	intact-crc:7A855A0F16DCC4EC|rigid:n8xaDXBFMDvl5rFgPgPLTz0dVjM	false	-	sufficient binding region:94-106	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A0G4PYZ0	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339717	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a0g4pyz0_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952327|imex:IM-25683-5	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:1B-4|comment:""\""HLA-DRB1*0801 allele  Inhibitor: HLA-DRB1*0101\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:2b6WKV5vcA/AaS5iDadYN7Pfcl49606	intact-crc:8F31543EDC923B27|rigid:bDUG78mQ4usuMaASQMjuQGyRUMk	false	-	sufficient binding region:94-106|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:D7RIG0	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339681	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:d7rig0_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952327|imex:IM-25683-5	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"go:""GO:0042613""(MHC class II protein complex)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|go:""GO:0016021""|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)"	-	-	no-uniprot-update:	"figure legend:1B-4|comment:""\""HLA-DRB1*0801 allele  Inhibitor: HLA-DRB1*0101\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:vCNdHdbtlKcoI2NPKfDiiFm88sQ9606	intact-crc:8F31543EDC923B27|rigid:bDUG78mQ4usuMaASQMjuQGyRUMk	false	-	sufficient binding region:94-106	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A0G4PYZ0	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339717	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a0g4pyz0_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952353|imex:IM-25683-6	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:1B-5|comment:""\""HLA-DRB1*0801 allele  Inhibitor: HLA-DRB1*0801\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:2b6WKV5vcA/AaS5iDadYN7Pfcl49606	intact-crc:5CA194C92EF1750C|rigid:70m8ITc/UxKiPAoi1bwg+EQ3F6M	false	-	sufficient binding region:94-106|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A0G4PYZ0	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339717	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a0g4pyz0_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952353|imex:IM-25683-6	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:1B-5|comment:""\""HLA-DRB1*0801 allele  Inhibitor: HLA-DRB1*0801\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:2b6WKV5vcA/AaS5iDadYN7Pfcl49606	intact-crc:5CA194C92EF1750C|rigid:70m8ITc/UxKiPAoi1bwg+EQ3F6M	false	-	sufficient binding region:94-106	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P04233	uniprotkb:P0A6Y8	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-542092|uniprotkb:P04475	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952558|imex:IM-25683-7	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	-	-	-	figure legend:2A|comment:The DRB1*0402 peptide did not inhibit binding, but all other peptides tested did.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	intact-crc:9BE6ED8DB51B9039|rigid:CDgHJV5M4P1skZFsvqD7JQLV6fk	false	sufficient binding region:105-117|biotin tag:?-?	-	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A0G4PYZ0	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339717	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a0g4pyz0_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952570|imex:IM-25683-8	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:2A-7|comment:""\""Inhibitor:HLA-DRB1*0801 allele\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:2b6WKV5vcA/AaS5iDadYN7Pfcl49606	intact-crc:0B5046CF9EF266EC|rigid:oG7rUlwrETaTVrKoP7D0j7mxgAo	false	-	sufficient binding region:94-106|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:P04233	intact:EBI-542092|uniprotkb:P04475	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952570|imex:IM-25683-8	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	-	-	-	"figure legend:2A-7|comment:""\""Inhibitor:HLA-DRB1*0801 allele\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:0B5046CF9EF266EC|rigid:oG7rUlwrETaTVrKoP7D0j7mxgAo	false	-	sufficient binding region:105-117	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:P04233	intact:EBI-542092|uniprotkb:P04475	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952584|imex:IM-25683-9	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	-	-	-	"figure legend:2A-1|comment:""\""Inhibitor: HLA-DRB1*0401\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:515BB980CC91D7C5|rigid:Eyy/O8q8ZDosgTHK+0fGj5nb2+A	false	-	sufficient binding region:105-117|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A1V1IGJ9	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339774	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a1v1igj9_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952584|imex:IM-25683-9	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:2A-1|comment:""\""Inhibitor: HLA-DRB1*0401\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:t0oiEebDmTMAhQ97YLbgIkwvFek9606	intact-crc:515BB980CC91D7C5|rigid:Eyy/O8q8ZDosgTHK+0fGj5nb2+A	false	-	sufficient binding region:94-106	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:P04233	intact:EBI-542092|uniprotkb:P04475	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952637|imex:IM-25683-10	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	-	-	-	"figure legend:2A-4|comment:""\""Inhibitor: HLA-DRB1*0101\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:4C189FC3376B07CD|rigid:eQpcuMBpRWb6z385Bf+TWuYalqw	false	-	sufficient binding region:105-117|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:D7RIG0	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339681	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:d7rig0_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952637|imex:IM-25683-10	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"go:""GO:0042613""(MHC class II protein complex)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|go:""GO:0016021""|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)"	-	-	no-uniprot-update:	"figure legend:2A-4|comment:""\""Inhibitor: HLA-DRB1*0101\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:vCNdHdbtlKcoI2NPKfDiiFm88sQ9606	intact-crc:4C189FC3376B07CD|rigid:eQpcuMBpRWb6z385Bf+TWuYalqw	false	-	sufficient binding region:94-106	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:P04233	intact:EBI-542092|uniprotkb:P04475	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952657|imex:IM-25683-11	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	-	-	-	"figure legend:2A-5|comment:""\""Inhibitor:HLA-DRB1*0901/DRB1*090102 allele (0901 sequence  shown to contain errors and be identical to DRB1*09:01:02 (December 1996)).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:7E9545CED20F87E0|rigid:rtKh8ScGmyJZEtIl7KWq24/hyJY	false	-	sufficient binding region:105-117|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:Q0R326	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339756	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:q0r326_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)|uniprotkb:HLA-DRB5(gene name synonym)|uniprotkb:hCG_1998957(orf name)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952657|imex:IM-25683-11	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|go:""GO:0016021""|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)"	-	-	no-uniprot-update:	"figure legend:2A-5|comment:""\""Inhibitor:HLA-DRB1*0901/DRB1*090102 allele (0901 sequence  shown to contain errors and be identical to DRB1*09:01:02 (December 1996)).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:Gq4S+WP70PV3KhQds27aWYtFaB09606	intact-crc:7E9545CED20F87E0|rigid:rtKh8ScGmyJZEtIl7KWq24/hyJY	false	-	sufficient binding region:94-106	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:P04233	intact:EBI-542092|uniprotkb:P04475	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952685|imex:IM-25683-12	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	-	-	-	"figure legend:2A-6|comment:""\""Inhibitor: HLA-DRB1*0403\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:04D80AAB9AD66FC3|rigid:Eyy/O8q8ZDosgTHK+0fGj5nb2+A	false	-	sufficient binding region:105-117|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:A0A1V1IGJ9	intact:EBI-542092|uniprotkb:P04475	intact:EBI-25339774	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:a0a1v1igj9_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952685|imex:IM-25683-12	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)	-	-	no-uniprot-update:	"figure legend:2A-6|comment:""\""Inhibitor: HLA-DRB1*0403\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:t0oiEebDmTMAhQ97YLbgIkwvFek9606	intact-crc:04D80AAB9AD66FC3|rigid:Eyy/O8q8ZDosgTHK+0fGj5nb2+A	false	-	sufficient binding region:94-106|mutation:103-103,100-100	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:P04233	intact:EBI-542092|uniprotkb:P04475	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952702|imex:IM-25683-13	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	-	-	-	figure legend:2A-8|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:DBC92A47D204B219|rigid:CDgHJV5M4P1skZFsvqD7JQLV6fk	false	-	sufficient binding region:105-117|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:P04233	intact:EBI-542092|uniprotkb:P04475	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952702|imex:IM-25683-13	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	-	-	-	figure legend:2A-8|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:DBC92A47D204B219|rigid:CDgHJV5M4P1skZFsvqD7JQLV6fk	false	-	sufficient binding region:105-117	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:P04233	intact:EBI-542092|uniprotkb:P04475	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952714|imex:IM-25683-14	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	-	-	-	figure legend:2A-9|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:CC35C4251420BADA|rigid:5ivsGaUrJ00NOCNPCHGgg39rbr4	false	-	sufficient binding region:105-117|biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
intact:EBI-11820565	uniprotkb:P04958	-	intact:EBI-13951617	psi-mi:hspa1a_hspa1b_human-1(display_short)|psi-mi:EBI-11820565(display_long)|uniprotkb:hspa1a_hspa1b_human-1(gene name)	psi-mi:tetx_clote(display_long)|uniprotkb:tetX(gene name)|psi-mi:tetX(display_short)|uniprotkb:Tentoxylysin(gene name synonym)|uniprotkb:CTC_p60(locus name)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:212717(""Clostridium tetani (strain Massachusetts / E88)"")|taxid:212717(""Clostridium tetani (strain Massachusetts / E88)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952752|imex:IM-25683-17	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:1304""(molecule set)"	"psi-mi:""MI:0326""(protein)"	-	"rcsb pdb:7OH0|rcsb pdb:7OH1|rcsb pdb:1Z7H|rcsb pdb:3HMY|rcsb pdb:3HN1|rcsb pdb:4J1L|reactome:R-HSA-5250982|rcsb pdb:1DIW|rcsb pdb:1DLL|rcsb pdb:1YYN|refseq:WP_011100836.1|rcsb pdb:1A8D|rcsb pdb:1AF9|rcsb pdb:1D0H|rcsb pdb:1DFQ|rcsb pdb:1FV2|rcsb pdb:1FV3|rcsb pdb:1YVG|rcsb pdb:1YXW|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR012500(Clostridium neurotoxin, translocation)|rcsb pdb:5N0B|rcsb pdb:5N0C|interpro:IPR036248|rcsb pdb:7BXX|rcsb pdb:7BY4|rcsb pdb:7BY5|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0044079""(symbiont-mediated perturbation of host neurotransmitter secretion)|go:""GO:0090729""(toxin activity)"	-	comment:P0DMV8,P0DMV9	-	"figure legend:2Bii|comment:""\""Unlabeled CLIP peptide as well as a peptide from tetanus toxin (TT 947–966) showed  stronger competition as compared to the HLA-DR-derived peptide fragments.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2025/03/25	-	rogid:arI9eRMHUPPu5ZWeO5ET1JoJKB0212717	intact-crc:97024957502601B7	false	-	sufficient binding region:947-966	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P0A6Y8	uniprotkb:P01911	intact:EBI-542092|uniprotkb:P04475	intact:EBI-1033104|uniprotkb:O19717|uniprotkb:O19739|uniprotkb:P13759|uniprotkb:Q29875|uniprotkb:Q30145|uniprotkb:Q9GIX9|uniprotkb:Q9GIY4|uniprotkb:Q9MY13|uniprotkb:Q9XRY5|ensembl:ENSP00000353099.5|uniprotkb:A0MWF2|uniprotkb:A0N0W1|uniprotkb:A2ICT1|uniprotkb:A2TGX3|uniprotkb:A4F5N0|uniprotkb:A4ZXA5|uniprotkb:A4ZXA6|uniprotkb:A4ZY86|uniprotkb:A5H000|uniprotkb:A5HKN8|uniprotkb:A7DZP9|uniprotkb:A7LA26|uniprotkb:A7UHG2|uniprotkb:A7X5B1|uniprotkb:A7X5B7|uniprotkb:A7X5E0|uniprotkb:A7X5E6|uniprotkb:A7X5H8|uniprotkb:A7X5J4|uniprotkb:A7X5K7|uniprotkb:A8K098|uniprotkb:A8YQE9|uniprotkb:A9JPG0|uniprotkb:B0BK85|uniprotkb:B1GWE7|uniprotkb:B2CR03|uniprotkb:B0LUZ6|uniprotkb:B0UYW1|uniprotkb:B2LVF9|uniprotkb:B2NJ29|uniprotkb:B2ZCY1|uniprotkb:B3VTP8|uniprotkb:B3VTQ3|uniprotkb:B5A8Y2|uniprotkb:B5A8Y3|uniprotkb:C0LAB5|uniprotkb:B5B8U0|uniprotkb:B5B9V5|uniprotkb:B5B9V6|uniprotkb:B5LZ25|uniprotkb:B5QSK8|uniprotkb:B6VCX2|uniprotkb:B6VEL9|uniprotkb:B7UDB2|uniprotkb:B9VRA4|uniprotkb:B9X248|uniprotkb:Q0PGR5|uniprotkb:O02876|uniprotkb:O02930|uniprotkb:O19585|uniprotkb:O19718|uniprotkb:O19788|uniprotkb:O46699|uniprotkb:O46793|uniprotkb:O46872|uniprotkb:O62869|uniprotkb:O62889|uniprotkb:O77969|uniprotkb:O78047|uniprotkb:O78210|uniprotkb:O98212|uniprotkb:P01912|uniprotkb:P01914|uniprotkb:P04229|uniprotkb:P13758|uniprotkb:P13760|uniprotkb:P13761|uniprotkb:P20039|uniprotkb:P79545|uniprotkb:Q06662|uniprotkb:Q0PQ39|uniprotkb:Q14280|uniprotkb:Q14QT2|uniprotkb:Q155F7|uniprotkb:Q19AF2|uniprotkb:Q19K86|uniprotkb:Q1AP33|uniprotkb:Q1G0Z9|uniprotkb:Q1JRP3|uniprotkb:Q1KLJ6|uniprotkb:Q27PR6|uniprotkb:Q27PR7|uniprotkb:Q29673|uniprotkb:Q29720|uniprotkb:Q29722|uniprotkb:Q29734|uniprotkb:Q29770|uniprotkb:Q29771|uniprotkb:Q768U2|uniprotkb:Q29772|uniprotkb:Q29790|uniprotkb:Q29792|uniprotkb:Q29800|uniprotkb:Q29806|uniprotkb:Q29833|uniprotkb:Q29874|uniprotkb:Q29886|uniprotkb:Q29968|uniprotkb:Q29974|uniprotkb:Q29975|uniprotkb:Q2A120|uniprotkb:Q2HZE5|uniprotkb:Q2L9H4|uniprotkb:Q2LE76|uniprotkb:Q2MF40|uniprotkb:Q2MJA6|uniprotkb:Q2MZ92|uniprotkb:Q2VQU1|uniprotkb:Q2YHQ2|uniprotkb:Q30006|uniprotkb:Q30108|uniprotkb:Q30112|uniprotkb:Q30115|uniprotkb:Q30116|uniprotkb:Q30117|uniprotkb:Q30120|uniprotkb:Q30134|uniprotkb:Q30142|uniprotkb:Q30149|uniprotkb:Q30159|uniprotkb:Q30166|uniprotkb:Q30167|uniprotkb:Q30200|uniprotkb:Q307W5|uniprotkb:Q31636|uniprotkb:Q32MY7|uniprotkb:Q3HUP9|uniprotkb:Q3KTM1|uniprotkb:Q3LA84|uniprotkb:Q3LA87|uniprotkb:Q3LA88|uniprotkb:Q3LA89|uniprotkb:Q3LA90|uniprotkb:Q3LA91|uniprotkb:Q3LA92|uniprotkb:Q3LA93|uniprotkb:Q3LA94|uniprotkb:Q3LA95|uniprotkb:Q3LA96|uniprotkb:Q3LA97|uniprotkb:Q3LA98|uniprotkb:Q3LA99|uniprotkb:Q3LAA0|uniprotkb:Q3LAA1|uniprotkb:Q3LAA2|uniprotkb:Q3MQ60|uniprotkb:Q3T919|uniprotkb:Q4PRC3|uniprotkb:Q4PRC5|uniprotkb:Q4VZY7|uniprotkb:Q53IG1|uniprotkb:Q56FN9|uniprotkb:Q56FP1|uniprotkb:Q56FP2|uniprotkb:Q56FP3|uniprotkb:Q58F52|uniprotkb:Q5BM92|uniprotkb:Q5EER6|uniprotkb:Q5K3W2|uniprotkb:Q5NDB9|uniprotkb:Q5U9W6|uniprotkb:Q5UBA2|uniprotkb:Q5UT58|uniprotkb:Q5W3L4|uniprotkb:Q5Y7A7|uniprotkb:Q5Y7B0|uniprotkb:Q5Y7B9|uniprotkb:Q5Y7E9|uniprotkb:Q5Y7G0|uniprotkb:Q683P7|uniprotkb:Q6REE2|uniprotkb:Q6T865|uniprotkb:Q6U387|uniprotkb:Q701T1|uniprotkb:Q70GL2|uniprotkb:Q70Q85|uniprotkb:Q768U4|uniprotkb:Q7M2H4|uniprotkb:Q7YNY9|uniprotkb:Q7YP03|uniprotkb:Q7YP04|uniprotkb:Q7YQ26|uniprotkb:Q7YQA3|uniprotkb:Q7YQA5|uniprotkb:Q860D8|uniprotkb:Q860D9|uniprotkb:Q860E5|uniprotkb:Q860H8|uniprotkb:Q860S0|uniprotkb:Q860Z3|uniprotkb:Q861G6|uniprotkb:Q861H0|uniprotkb:Q861H4|uniprotkb:Q861H5|uniprotkb:Q861H7|uniprotkb:Q861H8|uniprotkb:Q8HWQ6|uniprotkb:Q8MH59|uniprotkb:Q8MH60|uniprotkb:Q8WLU3|uniprotkb:Q8WMA0|uniprotkb:Q95348|uniprotkb:Q95383|uniprotkb:Q95389|uniprotkb:Q95461|uniprotkb:Q95HK1|uniprotkb:Q95HL0|uniprotkb:Q95HL1|uniprotkb:Q95IE3|uniprotkb:Q95IG2|uniprotkb:Q95IT6|uniprotkb:Q96HZ9|uniprotkb:Q9BCL7|uniprotkb:Q9BCP0|uniprotkb:Q9BCP1|uniprotkb:Q9BCP2|uniprotkb:Q9BCP5|uniprotkb:Q9BD21|uniprotkb:Q9BD33|uniprotkb:Q9BD40|uniprotkb:Q9GIK5|uniprotkb:Q9GIL5|uniprotkb:Q9GIL6|uniprotkb:Q9GIP3|uniprotkb:Q9GIX8|uniprotkb:Q9GIY0|uniprotkb:Q9GIY1|uniprotkb:Q9GIY2|intact:EBI-3866098|intact:EBI-13953066|uniprotkb:Q9GIY3|uniprotkb:Q9GJ25|uniprotkb:Q9GJ56|uniprotkb:Q9GJ57|uniprotkb:Q9GJ58|uniprotkb:Q9GJ60|uniprotkb:Q9GJF8|uniprotkb:Q9GJF9|uniprotkb:Q9GJG0|uniprotkb:Q9MXZ0|uniprotkb:Q9MXZ5|uniprotkb:Q9MY45|uniprotkb:Q9MY56|uniprotkb:Q9MYF5|uniprotkb:Q9TPB6|uniprotkb:Q9TPW1|uniprotkb:Q9TPW3|uniprotkb:Q9TPW9|uniprotkb:Q9TPX4|uniprotkb:Q9TQ37|uniprotkb:Q9TQ91|uniprotkb:Q9TQE0|uniprotkb:Q9UBY1|uniprotkb:Q9UIM9|uniprotkb:Q9UIN0|uniprotkb:Q9XRX1|uniprotkb:Q9XRY4|uniprotkb:Q9Y453|uniprotkb:Q9Y4H7|intact:EBI-13953170|intact:EBI-2877159	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:drb1_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)|uniprotkb:Human leukocyte antigen DRB1(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Haug et al. (2007)	imex:IM-25683|pubmed:17357109	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-13952864|imex:IM-25683-19	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)"	"ensembl:ENSG00000196126.12(gene)|ensembl:ENST00000360004.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002842""(positive regulation of T cell mediated immune response to tumor cell)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0008544""(epidermis development)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032653""(regulation of interleukin-10 production)|go:""GO:0032673""(regulation of interleukin-4 production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0042088""(T-helper 1 type immune response)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051262""(protein tetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01911|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FYT|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6HBY|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_001230894.1|refseq:NP_002115.2|refseq:XP_011546040.1|efo:""Orphanet:2073""|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:220407""|efo:""Orphanet:397""|efo:""Orphanet:477738""|efo:""Orphanet:536""|efo:""Orphanet:545""|efo:""Orphanet:703""|efo:""Orphanet:747""|efo:""Orphanet:797""|efo:""Orphanet:83465""|efo:""Orphanet:85414""|panther:PTHR19944(orthology-group)"	-	-	-	figure legend:4 A/Bi|comment:HLA-DRB1*0401  weak binding|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2024/11/14	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:YdQX0KNIxO5tYjgm6hdRRZfNlk49606	intact-crc:81EA93E9F9F8A20A|rigid:XSq0IpQRV6mu98tpgSv6JAJ5JC8	false	-	biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:O52302	uniprotkb:P62979	intact:EBI-14022357	intact:EBI-357375|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|ensembl:ENSP00000272317.6|ensembl:ENSP00000383981.3|ensembl:ENSP00000385659.1	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022383|imex:IM-25964-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	"refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1|ensembl:ENSG00000143947.15(gene)|ensembl:ENST00000272317.11(transcript)|ensembl:ENST00000402285.7(transcript)|ensembl:ENST00000404735.1(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006412""(translation)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019941""(modification-dependent protein catabolic process)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031386""(protein tag activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0032040""(small-subunit processome)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|interpro:IPR050158|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:5YDK|rcsb pdb:6DC6|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7BWD|rcsb pdb:7F0N|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|rcsb pdb:7MQ9|rcsb pdb:7MQA|rcsb pdb:7OOJ|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7WTT|rcsb pdb:7WTU|rcsb pdb:7WTV|rcsb pdb:7WTW|rcsb pdb:7WTX|rcsb pdb:7WTZ|rcsb pdb:7WU0|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8HTC|rcsb pdb:8HTF|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8IVB|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|rcsb pdb:9IPU|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866427|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-909733|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9680350|reactome:R-HSA-9683683|reactome:R-HSA-9692916|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-9725370|reactome:R-HSA-9735869|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-9754678|reactome:R-HSA-9755511|reactome:R-HSA-9758274|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9762114|reactome:R-HSA-977225|reactome:R-HSA-9824878|reactome:R-HSA-9828211|reactome:R-HSA-983168|reactome:R-HSA-9833109|reactome:R-HSA-9861718|panther:PTHR10666(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2017/04/02	2025/03/26	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606	intact-crc:A64B3D00D5FC832B|rigid:6gwmqFM30hDKiiPcHz/L3EwdB58	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O52302	uniprotkb:P08195	intact:EBI-14022357	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022383|imex:IM-25964-1	intact-miscore:0.59	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2017/04/02	2025/03/26	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	intact-crc:A64B3D00D5FC832B|rigid:6gwmqFM30hDKiiPcHz/L3EwdB58	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O52302	uniprotkb:P08238	intact:EBI-14022357	intact:EBI-352572|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0|ensembl:ENSP00000325875.3|ensembl:ENSP00000360609.1|ensembl:ENSP00000360709.5|ensembl:ENSP00000481908.1|intact:EBI-26518782	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:HSPC3(gene name synonym)|uniprotkb:Heat shock protein family C member 3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022383|imex:IM-25964-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	"refseq:NP_031381.2|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|ensembl:ENSG00000096384.20(gene)|ensembl:ENST00000353801.7(transcript)|ensembl:ENST00000371554.2(transcript)|ensembl:ENST00000371646.10(transcript)|ensembl:ENST00000620073.4(transcript)|go:""GO:0001890""(placenta development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007004""(telomere maintenance via telomerase)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019062""(virion attachment to host cell)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030235""(nitric-oxide synthase regulator activity)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030911""(TPR domain binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|rcsb pdb:8GFT|go:""GO:0032991""(protein-containing complex)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034751""(aryl hydrocarbon receptor complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042277""(peptide binding)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043008""(ATP-dependent protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044294""(dendritic growth cone)|go:""GO:0044295""(axonal growth cone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:0071353""(cellular response to interleukin-4)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0120293""(dynein axonemal particle)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1901799""(negative regulation of proteasomal protein catabolic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1905323""(telomerase holoenzyme complex assembly)|go:""GO:1990226""(histone methyltransferase binding)|go:""GO:1990565""(HSP90-CDC37 chaperone complex)|go:""GO:2000010""(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|rcsb pdb:7ULJ|rcsb pdb:7Z37|rcsb pdb:7Z38|rcsb pdb:7ZR0|rcsb pdb:7ZR5|rcsb pdb:7ZR6|rcsb pdb:7ZUB|rcsb pdb:8EOA|rcsb pdb:8EOB|rcsb pdb:8GAE|rcsb pdb:8QMO|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|reactome:R-HSA-9705671|reactome:R-HSA-9820962|reactome:R-HSA-9834752|dip:DIP-413N|panther:PTHR11528(orthology-group)|ensembl:ENSP00000325875.3|ensembl:ENSP00000360609.1|ensembl:ENSP00000360709.5|ensembl:ENSP00000481908.1"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2017/04/02	2025/03/26	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	rogid:wOsW7C10v2oMsM+REE38K6PAan09606	intact-crc:A64B3D00D5FC832B|rigid:6gwmqFM30hDKiiPcHz/L3EwdB58	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O52302	uniprotkb:P07900	intact:EBI-14022357	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9|ensembl:ENSP00000216281.8	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)|uniprotkb:Heat shock protein family C member 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022383|imex:IM-25964-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	"refseq:NP_001017963.2|refseq:NP_005339.3|ensembl:ENSG00000080824.19(gene)|ensembl:ENST00000216281.13(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0002134""(UTP binding)|go:""GO:0002135""(CTP binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0002230""(positive regulation of defense response to virus by host)|go:""GO:0003009""(skeletal muscle contraction)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006457""(protein folding)|go:""GO:0006839""(mitochondrial transport)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007004""(telomere maintenance via telomerase)|go:""GO:0009408""(response to heat)|go:""GO:0009409""(response to cold)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009651""(response to salt stress)|go:""GO:0009986""(cell surface)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010659""(cardiac muscle cell apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017098""(sulfonylurea receptor binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030235""(nitric-oxide synthase regulator activity)|go:""GO:0030911""(TPR domain binding)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031526""(brush border membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0032273""(positive regulation of protein polymerization)|go:""GO:0032564""(dATP binding)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042220""(response to cocaine)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043209""(myelin sheath)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043335""(protein unfolding)|go:""GO:0043627""(response to estrogen)|go:""GO:0044294""(dendritic growth cone)|go:""GO:0044295""(axonal growth cone)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045040""(protein insertion into mitochondrial outer membrane)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045793""(positive regulation of cell size)|go:""GO:0046677""(response to antibiotic)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051020""(GTPase binding)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0060452""(positive regulation of cardiac muscle contraction)|go:""GO:0061684""(chaperone-mediated autophagy)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097226""(sperm mitochondrial sheath)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098586""(cellular response to virus)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1902988""(neurofibrillary tangle assembly)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1905323""(telomerase holoenzyme complex assembly)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|rcsb pdb:1UY8|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2BYH|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2VCJ|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:3B24|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:3K99|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:3T0H|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:4YKZ|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|rcsb pdb:5LO1|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6CYH|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN4|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7DMC|rcsb pdb:7KRJ|rcsb pdb:7KW7|rcsb pdb:7L7I|rcsb pdb:7L7J|rcsb pdb:7LSZ|rcsb pdb:7LT0|rcsb pdb:7RXZ|rcsb pdb:7RY0|rcsb pdb:7RY1|rcsb pdb:7S8Y|rcsb pdb:7S8Z|rcsb pdb:7S90|rcsb pdb:7S95|rcsb pdb:7S98|rcsb pdb:7S99|rcsb pdb:7S9F|rcsb pdb:7S9G|rcsb pdb:7S9H|rcsb pdb:7S9I|rcsb pdb:7UR3|rcsb pdb:8AGI|rcsb pdb:8AGJ|rcsb pdb:8AGL|rcsb pdb:8B7I|rcsb pdb:8B7J|rcsb pdb:8FFV|rcsb pdb:8FFW|rcsb pdb:8KI4|rcsb pdb:8SBT|rcsb pdb:8W4V|rcsb pdb:8W8K|rcsb pdb:8X2R|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|reactome:R-HSA-9705671|reactome:R-HSA-9820962|reactome:R-HSA-9834752|dip:DIP-27595N|ensembl:ENSP00000335153.7|ensembl:ENSP00000216281.8|ensembl:ENST00000334701.11|panther:PTHR11528(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2017/04/02	2025/03/26	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	intact-crc:A64B3D00D5FC832B|rigid:6gwmqFM30hDKiiPcHz/L3EwdB58	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P08195	uniprotkb:O52302	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	intact:EBI-14022357	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022401|imex:IM-25964-3	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/04/02	2024/11/14	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:63424B1AE9A63D4F|rigid:TaSgkNFpMY426/PB9oRcUQdV4TI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08962	uniprotkb:O52302	intact:EBI-762053|ensembl:ENSP00000257857.4|ensembl:ENSP00000393502.3|ensembl:ENSP00000447730.1|ensembl:ENSP00000449337.1|uniprotkb:Q5TZP3|uniprotkb:Q9UCG6|uniprotkb:Q8N6Z9|uniprotkb:F8VZE2	intact:EBI-14022357	psi-mi:cd63_human(display_long)|uniprotkb:Melanoma-associated antigen ME491(gene name synonym)|uniprotkb:Ocular melanoma-associated antigen(gene name synonym)|uniprotkb:OMA81H(gene name synonym)|uniprotkb:Granulophysin(gene name synonym)|uniprotkb:Tetraspanin-30(gene name synonym)|uniprotkb:Lysosomal-associated membrane protein 3(gene name synonym)|uniprotkb:CD63(gene name)|psi-mi:CD63(display_short)|uniprotkb:MLA1(gene name synonym)|uniprotkb:TSPAN30(gene name synonym)|uniprotkb:Lysosome integral membrane protein 1(gene name synonym)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022405|imex:IM-25964-21	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001771.1|ensembl:ENSG00000135404.12(gene)|ensembl:ENST00000257857.9(transcript)|ensembl:ENST00000420846.7(transcript)|ensembl:ENST00000549117.5(transcript)|ensembl:ENST00000552692.5(transcript)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016477""(cell migration)|go:""GO:0031088""(platelet dense granule membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031904""(endosome lumen)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0042470""(melanosome)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048757""(pigment granule maturation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097487""(multivesicular body, internal vesicle)|go:""GO:1900746""(regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042028|mint:P08962|reactome:R-HSA-114608|reactome:R-HSA-6798695|refseq:NP_001244330.1|refseq:NP_001244318.1|refseq:NP_001244319.1|refseq:NP_001244320.1|refseq:NP_001244329.1|refseq:NP_001254627.1|refseq:NP_001244321.1|panther:PTHR19282(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/04/02	2024/11/14	rogid:stCGi5kkTMIdO84qSwjmjpUwwvs9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:1BA65531BBC33CF3|rigid:B25z22mO26sifMakaprCCNTz+78	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40967	uniprotkb:O52302	intact:EBI-14022409|uniprotkb:Q14817|uniprotkb:Q16565|uniprotkb:B3KS57|uniprotkb:B7Z6D7|uniprotkb:Q12763|uniprotkb:Q14448|ensembl:ENSP00000447374.1|ensembl:ENSP00000448828.1|ensembl:ENSP00000449690.1	intact:EBI-14022357	psi-mi:pmel_human(display_long)|uniprotkb:PMEL(gene name)|psi-mi:PMEL(display_short)|uniprotkb:D12S53E(gene name synonym)|uniprotkb:PMEL17(gene name synonym)|uniprotkb:SILV(gene name synonym)|uniprotkb:ME20-M(gene name synonym)|uniprotkb:Melanocyte protein Pmel 17(gene name synonym)|uniprotkb:Melanocytes lineage-specific antigen GP100(gene name synonym)|uniprotkb:Melanoma-associated ME20 antigen(gene name synonym)|uniprotkb:P1(gene name synonym)|uniprotkb:P100(gene name synonym)|uniprotkb:Premelanosome protein(gene name synonym)|uniprotkb:Silver locus protein homolog(gene name synonym)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022459|imex:IM-25964-5	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001186982.1|refseq:NP_001186983.1|refseq:NP_001307050.1|refseq:NP_001307051.1|refseq:NP_008859.1|refseq:XP_006719632.1|refseq:XP_011536987.1|dip:DIP-48937N|ensembl:ENSG00000185664.15(gene)|ensembl:ENST00000548493.5(transcript)|ensembl:ENST00000548747.6(transcript)|ensembl:ENST00000552882.5(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0032438""(melanosome organization)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033106""(cis-Golgi network membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0048023""(positive regulation of melanin biosynthetic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097487""(multivesicular body, internal vesicle)|interpro:IPR000601(PKD)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR022409|interpro:IPR035986|interpro:IPR045219|interpro:IPR046846|mint:P40967|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:3CC5|rcsb pdb:4IS6|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:7PHR|rcsb pdb:9JST|rcsb pdb:9JSU|rcsb pdb:9JSV|rcsb pdb:9JSW|rcsb pdb:9JSX|reactome:R-HSA-9824585|panther:PTHR11861(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/04/02	2025/01/15	rogid:m4tPA2808oiUqUUr4R5X9F8pTPo9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:98DAD647B1FEAC60|rigid:CpIEcCMSB/ZOzNqzDSToaMqrm5c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96DB9	uniprotkb:O52302	intact:EBI-14022463|uniprotkb:B7WNZ8|uniprotkb:Q6UW44|uniprotkb:Q9HC34|uniprotkb:Q9P039|ensembl:ENSP00000344254.3|ensembl:ENSP00000376053.2|ensembl:ENSP00000393848.2|ensembl:ENSP00000443390.1|ensembl:ENSP00000465667.1	intact:EBI-14022357	psi-mi:fxyd5_human(display_long)|uniprotkb:FXYD5(gene name)|psi-mi:FXYD5(display_short)|uniprotkb:DYSAD(gene name synonym)|uniprotkb:IWU1(gene name synonym)|uniprotkb:HSPC113(orf name)|uniprotkb:UNQ2561/PRO6241(orf name)|uniprotkb:Dysadherin(gene name synonym)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022502|imex:IM-25964-7	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001158077.1|refseq:NP_001307842.1|refseq:NP_054883.3|refseq:NP_659003.1|ensembl:ENSG00000089327.16(gene)|ensembl:ENST00000342879.7(transcript)|ensembl:ENST00000392219.7(transcript)|ensembl:ENST00000423817.7(transcript)|ensembl:ENST00000541435.6(transcript)|ensembl:ENST00000590686.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006813""(potassium ion transport)|go:""GO:0006814""(sodium ion transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0017080""(sodium channel regulator activity)|go:""GO:0030033""(microvillus assembly)|go:""GO:0045296""(cadherin binding)|go:""GO:0046588""(negative regulation of calcium-dependent cell-cell adhesion)|go:""GO:1903278""(positive regulation of sodium ion export across plasma membrane)|interpro:IPR000272(Ion-transport regulator, FXYD region)|interpro:IPR047297|panther:PTHR14132(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/04/02	2024/11/14	rogid:pJb+sLBO4y8knVsw+CkezSpZCCk9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:F9839495E0B3C0C0|rigid:5uR1XzvzBPkLPCjufpd+5IokSHw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P58340	uniprotkb:O52302	intact:EBI-721328|intact:EBI-767466|uniprotkb:E9PEU9|uniprotkb:Q2TLE5|uniprotkb:Q8N8F8|uniprotkb:Q96MH1|uniprotkb:Q2TLE3|ensembl:ENSP00000348157.5	intact:EBI-14022357	psi-mi:mlf1_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 1(gene name synonym)|uniprotkb:MLF1(gene name)|psi-mi:MLF1(display_short)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022506|imex:IM-25964-9	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_071888.1|refseq:NP_001182361.1|refseq:NP_001182362.1|refseq:NP_001182363.1|refseq:XP_011511154.1|refseq:NP_001123628.1|refseq:NP_001123629.1|refseq:XP_011511155.1|refseq:XP_005247537.1|ensembl:ENSG00000178053.21(gene)|ensembl:ENST00000355893.11(transcript)|go:""GO:0002318""(myeloid progenitor cell differentiation)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005929""(cilium)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0036064""(ciliary basal body)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1902806""(regulation of cell cycle G1/S phase transition)|interpro:IPR019376|mint:P58340|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6Y8E|panther:PTHR13105(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/04/02	2024/11/14	rogid:czY64xaocTjgRFAtZU19jvH4MIo9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:0CAC7D74697CC58A|rigid:T87kpJM/3cln1V/R+25df7n+i8Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01151	uniprotkb:O52302	intact:EBI-2873723|uniprotkb:Q5THX9|ensembl:ENSP00000368450.3	intact:EBI-14022357	psi-mi:cd83_human(display_long)|uniprotkb:CD83(gene name)|psi-mi:CD83(display_short)|uniprotkb:B-cell activation protein(gene name synonym)|uniprotkb:Cell surface protein HB15(gene name synonym)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022510|imex:IM-25964-11	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035370.1|refseq:NP_004224.1|refseq:NP_001238830.1|ensembl:ENSG00000112149.11(gene)|ensembl:ENST00000379153.4(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0032713""(negative regulation of interleukin-4 production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0043367""(CD4-positive, alpha-beta T cell differentiation)|go:""GO:0043372""(positive regulation of CD4-positive, alpha-beta T cell differentiation)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:5MIX|rcsb pdb:5MJ0|rcsb pdb:5MJ1|rcsb pdb:5MJ2|panther:PTHR15193(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/04/02	2024/11/14	rogid:ICaEMYG0gkpGAtk5ErEZlHZRcrU9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:F503075CB911980C|rigid:q3REYNBSzSCVR+ZzS6OxQk9RNP0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14209	uniprotkb:O52302	intact:EBI-748547|uniprotkb:O00518|uniprotkb:Q6ICV7|uniprotkb:A6NIW1|ensembl:ENSP00000370588.3|ensembl:ENSP00000518648.1	intact:EBI-14022357	psi-mi:cd99_human(display_long)|uniprotkb:T-cell surface glycoprotein E2(gene name synonym)|uniprotkb:E2 antigen(gene name synonym)|uniprotkb:Protein MIC2(gene name synonym)|uniprotkb:12E7(gene name synonym)|uniprotkb:CD99(gene name)|psi-mi:CD99(display_short)|uniprotkb:MIC2(gene name synonym)|uniprotkb:MIC2X(gene name synonym)|uniprotkb:MIC2Y(gene name synonym)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022514|imex:IM-25964-13	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001116370.1|refseq:NP_002405.1|ensembl:ENSG00000002586.20(gene)|ensembl:ENSG00000292348.1(gene)|ensembl:ENST00000381192.10(transcript)|ensembl:ENST00000711160.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0034109""(homotypic cell-cell adhesion)|go:""GO:0072683""(T cell extravasation)|go:""GO:2000391""(positive regulation of neutrophil extravasation)|interpro:IPR022078|mint:P14209|rcsb pdb:7SFX|reactome:R-HSA-198933|reactome:R-HSA-202733|refseq:NP_001308298.1|refseq:NP_001308296.1|refseq:NP_001308297.1|panther:PTHR15076(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/04/02	2024/11/14	rogid:g0uUrvPtgp5eBwP7RXnQa0Ij6GU9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:3A1FB50D94E28BDC|rigid:ZgeAHVSJepYM/k3jS+UI9CJySYg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15365	uniprotkb:O52302	intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556.5	intact:EBI-14022357	psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022518|imex:IM-25964-23	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006187.2|ensembl:ENSG00000169564.7(gene)|ensembl:ENST00000303577.7(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0039694""(viral RNA genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098847""(sequence-specific single stranded DNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-38136N|ensembl:ENSP00000305556.5|panther:PTHR10288(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/04/02	2025/03/24	rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:95C07AC4CE4CA064|rigid:YXI73AeFFVxCnyOL9usKoIDOPjQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z692	uniprotkb:O52302	intact:EBI-14022522|uniprotkb:Q5XJ15|uniprotkb:Q7Z693|ensembl:ENSP00000384887.3	intact:EBI-14022357	psi-mi:cea19_human(display_long)|uniprotkb:CEACAM19(gene name)|psi-mi:CEACAM19(display_short)|uniprotkb:CEAL1(gene name synonym)|uniprotkb:Carcinoembryonic antigen-like 1(gene name synonym)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 19(gene name synonym)|uniprotkb:UNQ2973/PRO7436(orf name)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022541|imex:IM-25964-25	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001121365.1|refseq:NP_064604.2|ensembl:ENSG00000186567.14(gene)|ensembl:ENST00000403660.3(transcript)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|panther:PTHR44337(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/04/02	2024/11/14	rogid:rTxW6wxwBH1I6yL1pUvLqRP8LzY9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:D582C70BD74BA2C4|rigid:QOtrpw+e/zyOX7PPtxGOZ77I15Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08195	uniprotkb:O52302	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	intact:EBI-14022357	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0663""(confocal microscopy)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022586|imex:IM-25964-15	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:4A-B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2017/04/02	2024/11/14	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:656ADA7001167873|rigid:TaSgkNFpMY426/PB9oRcUQdV4TI	false	flag tag:?-?	green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P08195	uniprotkb:O52302	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	intact:EBI-14022357	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022601|imex:IM-25964-17	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:4D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2017/04/02	2024/11/14	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:BD6DD658DE7715B2|rigid:TaSgkNFpMY426/PB9oRcUQdV4TI	false	flag tag:?-?	ha tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P08195	uniprotkb:O52302	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	intact:EBI-14022357	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	psi-mi:o52302_ecolx(display_long)|uniprotkb:sepZ(gene name)|psi-mi:sepZ(display_short)|uniprotkb:espZ(gene name synonym)|uniprotkb:B6R15_003114(orf name)|uniprotkb:NCTC8622_07612(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Shames et al. (2010)	pubmed:20374249|imex:IM-25964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022610|imex:IM-25964-19	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	"refseq:WP_000338345.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0140415""(effector-mediated perturbation of host defenses by symbiont)"	-	-	-	figure legend:4F|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2017/04/02	2024/11/14	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	rogid:cu7EZCQAAnfrCeatALdw7beaSF8562	intact-crc:8FA97DC6E7D7279B|rigid:TaSgkNFpMY426/PB9oRcUQdV4TI	false	flag tag:?-?	green fluorescent protein tag:?-?|necessary binding region:43-99	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q7DB68	uniprotkb:O60830	intact:EBI-14029721|uniprotkb:A0A6M0JMB5|uniprotkb:Q7A9P1|uniprotkb:A0A0H3JLG1	intact:EBI-2372529|uniprotkb:Q9UJV0|uniprotkb:A8K2E2|uniprotkb:J3KPV3|ensembl:ENSP00000365766.3|ensembl:ENSP00000512416.1|ensembl:ENSP00000518047.1|ensembl:ENSP00000518049.1	psi-mi:q7db68_eco57(display_long)|uniprotkb:ECs_4571(orf name)|uniprotkb:espZ(gene name)|psi-mi:espZ(display_short)	psi-mi:ti17b_human(display_long)|uniprotkb:TIMM17B(gene name)|psi-mi:TIMM17B(display_short)|uniprotkb:TIM17B(gene name synonym)|uniprotkb:JM3(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Shames et al. (2011)	pubmed:21947777|imex:IM-25965	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14022352|imex:IM-25965-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_312598.1|refseq:WP_000386949.1|interpro:IPR009275(SepZ)|go:""GO:0016020""(membrane)"	"ensembl:ENSG00000126768.13(gene)|ensembl:ENSG00000292215.1(gene)|ensembl:ENST00000376582.7(transcript)|ensembl:ENST00000696123.1(transcript)|ensembl:ENST00000710085.1(transcript)|ensembl:ENST00000710087.1(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005744""(TIM23 mitochondrial import inner membrane translocase complex)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0030150""(protein import into mitochondrial matrix)|interpro:IPR005678(Mitochondrial import inner membrane translocase, subunit Tim17)|mint:O60830|reactome:R-HSA-1268020|refseq:NP_001161419.1|refseq:NP_005825.1|panther:PTHR10485(orthology-group)"	-	-	-	figure legend:3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2017/04/02	2024/11/14	rogid:nI1+GF7rSBrjyr8cM1Ea2yMoBrg83334	rogid:2jmF1ZItisqPDfdGgX/bY9FFE9E9606	intact-crc:AE3F31ECCCF09BAE|rigid:r634n6yh/bueX9Mgh4UPtQGwIfY	false	green fluorescent protein tag:c-c	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P08191	uniprotkb:O00322	intact:EBI-1028015|uniprotkb:Q2M5Z3	intact:EBI-14031976|ensembl:ENSP00000222275.2|uniprotkb:Q3KNU5|uniprotkb:Q3KNU6	psi-mi:fimh_ecoli(display_long)|uniprotkb:fimH(gene name)|psi-mi:fimH(display_short)|uniprotkb:Protein FimH(gene name synonym)|uniprotkb:JW4283(locus name)|uniprotkb:b4320(locus name)	psi-mi:upk1a_human(display_long)|uniprotkb:UPK1A(gene name)|psi-mi:UPK1A(display_short)|uniprotkb:TSPAN21(gene name synonym)|uniprotkb:Uroplakin Ia(gene name synonym)|uniprotkb:Tetraspanin-21(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Hashimoto et al. (2017)	pubmed:28228557|imex:IM-26025	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14032028|imex:IM-26025-3	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_418740.1|refseq:WP_000832247.1|dip:DIP-9616N|go:""GO:0005537""(D-mannose binding)|go:""GO:0007155""(cell adhesion)|go:""GO:0007638""(mechanosensory behavior)|go:""GO:0009289""(pilus)|go:""GO:0009419""(pilus tip)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033644""(host cell membrane)|go:""GO:0043709""(cell adhesion involved in single-species biofilm formation)|interpro:IPR000259(Fimbrial protein)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR015243(FimH, mannose-binding)|interpro:IPR036937|interpro:IPR050263|rcsb pdb:1KIU|rcsb pdb:1KLF|rcsb pdb:1QUN|rcsb pdb:1TR7|rcsb pdb:1UWF|rcsb pdb:1ZE3|rcsb pdb:2VCO|rcsb pdb:3RFZ|rcsb pdb:3ZL1|rcsb pdb:3ZL2|rcsb pdb:4ATT|rcsb pdb:4AUJ|rcsb pdb:4AUU|rcsb pdb:4AUY|rcsb pdb:4AV0|rcsb pdb:4AV4|rcsb pdb:4AV5|rcsb pdb:4AVH|rcsb pdb:4AVI|rcsb pdb:4AVJ|rcsb pdb:4AVK|rcsb pdb:4CSS|rcsb pdb:4CST|rcsb pdb:4J3O|rcsb pdb:4LOV|rcsb pdb:4X50|rcsb pdb:4X5P|rcsb pdb:4X5Q|rcsb pdb:4X5R|rcsb pdb:4XO8|rcsb pdb:4XO9|rcsb pdb:4XOA|rcsb pdb:4XOB|rcsb pdb:4XOD|rcsb pdb:5ABZ|rcsb pdb:5CGB|rcsb pdb:5F2F|rcsb pdb:5F3F|rcsb pdb:5FS5|rcsb pdb:5FWR|rcsb pdb:5FX3|rcsb pdb:5JCQ|rcsb pdb:5JCR|rcsb pdb:5L4T|rcsb pdb:5L4U|rcsb pdb:5L4V|rcsb pdb:5L4W|rcsb pdb:5L4X|rcsb pdb:5L4Y|rcsb pdb:5MCA|rcsb pdb:5MTS|rcsb pdb:5MUC|rcsb pdb:6E14|rcsb pdb:6E15|rcsb pdb:6G2R|rcsb pdb:6G2S|rcsb pdb:6GTX|rcsb pdb:6GTY|rcsb pdb:6YHW|rcsb pdb:7AYN|rcsb pdb:7BHD|rcsb pdb:7QUO|rcsb pdb:7SZO|rcsb pdb:8BVD|rcsb pdb:8BXY|rcsb pdb:8BY3|rcsb pdb:9BOG|panther:PTHR33420(orthology-group)"	"ensembl:ENSG00000105668.8(gene)|ensembl:ENST00000222275.3(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120001""(apical plasma membrane urothelial plaque)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|mint:O00322|refseq:NP_001268372.1|refseq:NP_008931.1|panther:PTHR19282(orthology-group)"	-	-	-	figure legend:7B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/04/13	2024/11/14	rogid:5DDG/zwwZi4t597Dk1JZiEj5Leo83333	rogid:/W9BzFoQXsagQQwLySUl280GnQk9606	intact-crc:4CFFB98A687F9E85|rigid:1Upbh9C/Vus2kb9KeRXu69PqV9c	false	binding-associated region:1-181	flag tag:c-c	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:O00322	uniprotkb:P08191	intact:EBI-14031976|ensembl:ENSP00000222275.2|uniprotkb:Q3KNU5|uniprotkb:Q3KNU6	intact:EBI-1028015|uniprotkb:Q2M5Z3	psi-mi:upk1a_human(display_long)|uniprotkb:UPK1A(gene name)|psi-mi:UPK1A(display_short)|uniprotkb:TSPAN21(gene name synonym)|uniprotkb:Uroplakin Ia(gene name synonym)|uniprotkb:Tetraspanin-21(gene name synonym)	psi-mi:fimh_ecoli(display_long)|uniprotkb:fimH(gene name)|psi-mi:fimH(display_short)|uniprotkb:Protein FimH(gene name synonym)|uniprotkb:JW4283(locus name)|uniprotkb:b4320(locus name)	"psi-mi:""MI:0892""(solid phase assay)"	Hashimoto et al. (2017)	pubmed:28228557|imex:IM-26025	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-14032034|imex:IM-26025-5	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105668.8(gene)|ensembl:ENST00000222275.3(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120001""(apical plasma membrane urothelial plaque)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|mint:O00322|refseq:NP_001268372.1|refseq:NP_008931.1|panther:PTHR19282(orthology-group)"	"refseq:NP_418740.1|refseq:WP_000832247.1|dip:DIP-9616N|go:""GO:0005537""(D-mannose binding)|go:""GO:0007155""(cell adhesion)|go:""GO:0007638""(mechanosensory behavior)|go:""GO:0009289""(pilus)|go:""GO:0009419""(pilus tip)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033644""(host cell membrane)|go:""GO:0043709""(cell adhesion involved in single-species biofilm formation)|interpro:IPR000259(Fimbrial protein)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR015243(FimH, mannose-binding)|interpro:IPR036937|interpro:IPR050263|rcsb pdb:1KIU|rcsb pdb:1KLF|rcsb pdb:1QUN|rcsb pdb:1TR7|rcsb pdb:1UWF|rcsb pdb:1ZE3|rcsb pdb:2VCO|rcsb pdb:3RFZ|rcsb pdb:3ZL1|rcsb pdb:3ZL2|rcsb pdb:4ATT|rcsb pdb:4AUJ|rcsb pdb:4AUU|rcsb pdb:4AUY|rcsb pdb:4AV0|rcsb pdb:4AV4|rcsb pdb:4AV5|rcsb pdb:4AVH|rcsb pdb:4AVI|rcsb pdb:4AVJ|rcsb pdb:4AVK|rcsb pdb:4CSS|rcsb pdb:4CST|rcsb pdb:4J3O|rcsb pdb:4LOV|rcsb pdb:4X50|rcsb pdb:4X5P|rcsb pdb:4X5Q|rcsb pdb:4X5R|rcsb pdb:4XO8|rcsb pdb:4XO9|rcsb pdb:4XOA|rcsb pdb:4XOB|rcsb pdb:4XOD|rcsb pdb:5ABZ|rcsb pdb:5CGB|rcsb pdb:5F2F|rcsb pdb:5F3F|rcsb pdb:5FS5|rcsb pdb:5FWR|rcsb pdb:5FX3|rcsb pdb:5JCQ|rcsb pdb:5JCR|rcsb pdb:5L4T|rcsb pdb:5L4U|rcsb pdb:5L4V|rcsb pdb:5L4W|rcsb pdb:5L4X|rcsb pdb:5L4Y|rcsb pdb:5MCA|rcsb pdb:5MTS|rcsb pdb:5MUC|rcsb pdb:6E14|rcsb pdb:6E15|rcsb pdb:6G2R|rcsb pdb:6G2S|rcsb pdb:6GTX|rcsb pdb:6GTY|rcsb pdb:6YHW|rcsb pdb:7AYN|rcsb pdb:7BHD|rcsb pdb:7QUO|rcsb pdb:7SZO|rcsb pdb:8BVD|rcsb pdb:8BXY|rcsb pdb:8BY3|rcsb pdb:9BOG|panther:PTHR33420(orthology-group)"	-	-	-	figure legend:7D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/04/13	2024/11/14	rogid:/W9BzFoQXsagQQwLySUl280GnQk9606	rogid:5DDG/zwwZi4t597Dk1JZiEj5Leo83333	intact-crc:9E40250CB7FD9FFC|rigid:RBpzagyTa5FOJhaBE2DYb5MfQ+E	false	flag tag:c-c	binding-associated region:1-181|his tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P75390	uniprotkb:P00747	intact:EBI-2259629	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2015)	pubmed:26667841|imex:IM-26055	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12654874|imex:IM-26055-1	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:S2 & 5|antagonist:Epsilon-aminocaproic acid|antagonist:sodium chloride|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/02	2024/11/14	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:CA44EB88AB8FA0D2|rigid:pMM/RJTnIsj6CPlD4V89Tdars2Y	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P00747	intact:EBI-2259621	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2015)	pubmed:26667841|imex:IM-26055	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12654938|imex:IM-26055-3	intact-miscore:0.83	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:S2 & 5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/02	2024/11/14	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:374996A2A7A453A9|rigid:rbpPnM94cb3alyoiXVn/sGuf2U8	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75392	uniprotkb:P00747	intact:EBI-2259593	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2015)	pubmed:26667841|imex:IM-26055	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12654944|imex:IM-26055-5	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:S2 & 5|antagonist:Epsilon-aminocaproic acid|antagonist:sodium chloride|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/02	2024/11/14	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:569829687F99B7F8|rigid:eS02w0gHvYCoXmR1a3oFRkvl02s	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75358	uniprotkb:P00747	intact:EBI-2259469	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2015)	pubmed:26667841|imex:IM-26055	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12654950|imex:IM-26055-7	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:S2 & 5|antagonist:sodium chloride|antagonist:ACA- Epsilon-aminocaproic acid|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/02	2024/11/14	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:C5E3EBB198C306F6|rigid:w9pOF9ZIrTb+jcwn9NOVQHxOQJg	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75167	uniprotkb:P00747	intact:EBI-2259565	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:gpmi_mycpn(display_long)|uniprotkb:pgm(gene name synonym)|uniprotkb:MP214(orf name)|uniprotkb:MPN_628(locus name)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2015)	pubmed:26667841|imex:IM-26055	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12654967|imex:IM-26055-9	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|refseq:NP_110317.1|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0030145""(manganese ion binding)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|go:""GO:0051919""(positive regulation of fibrinolysis)|refseq:WP_010874985.1|interpro:IPR036646"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:S2 & 5|antagonist:Epsilon-aminocaproic acid|antagonist:sodium choloride|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/02	2024/11/14	rogid:HrxbL8sfnlZRkDD3zllGqh7xdMg272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:89B41E73CCECEAFD|rigid:ridJBXajYheii8rnNKK2Uk+dz10	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78031	uniprotkb:P00747	intact:EBI-2259473	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:kpyk_mycpn(display_long)|uniprotkb:MP533(orf name)|uniprotkb:MPN_303(locus name)|uniprotkb:pyk(gene name)|psi-mi:pyk(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2015)	pubmed:26667841|imex:IM-26055	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12654973|imex:IM-26055-11	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_109991.1|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031639""(plasminogen activation)|refseq:WP_010874660.1|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:S2 & 5|antagonist:Epsilon-aminocaproic acid|antagonist:sodium chloride|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/02	2024/11/14	rogid:ovUfpbDSZQd3WYZ9w4bChqq6oR4272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:05C402B7A57F6983|rigid:jrpVXiWiKmqtXdGDnM6N++QeM8I	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75611	uniprotkb:P00747	intact:EBI-12654979	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:tkt_mycpn(display_long)|uniprotkb:tktA(gene name synonym)|uniprotkb:tkt(gene name)|psi-mi:tkt(display_short)|uniprotkb:MP073(orf name)|uniprotkb:MPN_082(locus name)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2015)	pubmed:26667841|imex:IM-26055	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12654998|imex:IM-26055-13	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0016020""(membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR033247|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR029061|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|refseq:NP_109770.1|refseq:WP_010874439.1"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:S2 & 5|antagonist:Epsilon-aminocaproic acid|antagonist:sodium chloride|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/02	2024/11/14	rogid:BhDXt/cNzav8lYxIgkE2jdHpa7c272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:541D3E24A665313C|rigid:Dq245kr6F1fYbOg40IX1p5wEDKw	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78007	uniprotkb:P00747	intact:EBI-2260877	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:ldh_mycpn(display_long)|uniprotkb:MP168(orf name)|uniprotkb:MPN_674(locus name)|uniprotkb:ldh(gene name)|psi-mi:ldh(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2015)	pubmed:26667841|imex:IM-26055	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12655004|imex:IM-26055-15	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|refseq:NP_110363.1|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR018177|interpro:IPR022383|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|refseq:WP_010875031.1|interpro:IPR036291"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:S2 & 5|antagonist:Epsilon-aminocaproic acid|antagonist:sodium chloride|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/02	2024/11/14	rogid:dQR2ufgJU2G1Fa0OPl+ME9jTUDw272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:ECE3F73549FB4DE0|rigid:diqbdi8z9LBz6M7WsAnOESwdtOc	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75390	uniprotkb:P02788	intact:EBI-2259629	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12735276|imex:IM-25880-70	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/01/19	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:DF56AE350ABD051A	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P02788	intact:EBI-2259621	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917383|imex:IM-25880-50	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/01/19	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:3626AE350ABD6135	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75392	uniprotkb:P02788	intact:EBI-2259593	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917388|imex:IM-25880-52	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/01/19	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:BDB6AE350ABDCD45	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75358	uniprotkb:P02788	intact:EBI-2259469	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917393|imex:IM-25880-30	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/01/19	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:52F8EE350ABE26D6	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78031	uniprotkb:P02788	intact:EBI-2259473	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:kpyk_mycpn(display_long)|uniprotkb:MP533(orf name)|uniprotkb:MPN_303(locus name)|uniprotkb:pyk(gene name)|psi-mi:pyk(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917398|imex:IM-25880-32	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_109991.1|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031639""(plasminogen activation)|refseq:WP_010874660.1|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/01/19	rogid:ovUfpbDSZQd3WYZ9w4bChqq6oR4272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:E5D6BCF23ABD62DC	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75390	uniprotkb:P04004	intact:EBI-2259629	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917882|imex:IM-25880-34	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:E57B6F5DAF0941A0	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P04004	intact:EBI-2259621	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917888|imex:IM-25880-36	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:0C0B6F5DAF09258F	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75392	uniprotkb:P04004	intact:EBI-2259593	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917894|imex:IM-25880-19	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:135.84x10^-8 ~77.03(molar)	2016/12/15	2025/03/10	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:DC6467E6B45F03BA|rigid:Y5T1tXmsve0aM2X8vGoTu2J8khk	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75167	uniprotkb:P04004	intact:EBI-2259565	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:gpmi_mycpn(display_long)|uniprotkb:pgm(gene name synonym)|uniprotkb:MP214(orf name)|uniprotkb:MPN_628(locus name)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917900|imex:IM-25880-21	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|refseq:NP_110317.1|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0030145""(manganese ion binding)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|go:""GO:0051919""(positive regulation of fibrinolysis)|refseq:WP_010874985.1|interpro:IPR036646"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:8.99x10^-8 ~3.78(molar)	2016/12/15	2025/03/10	rogid:HrxbL8sfnlZRkDD3zllGqh7xdMg272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:BE8F4506B45EF536|rigid:wA7DjRqYNVO8GLmYz/iyQqMmE9g	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75358	uniprotkb:P04004	intact:EBI-2259469	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917905|imex:IM-25880-38	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:68D52F5DAF0A626C	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78031	uniprotkb:P04004	intact:EBI-2259473	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:kpyk_mycpn(display_long)|uniprotkb:MP533(orf name)|uniprotkb:MPN_303(locus name)|uniprotkb:pyk(gene name)|psi-mi:pyk(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917911|imex:IM-25880-40	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_109991.1|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031639""(plasminogen activation)|refseq:WP_010874660.1|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:ovUfpbDSZQd3WYZ9w4bChqq6oR4272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:DFFB7D9A9F092666	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75611	uniprotkb:P04004	intact:EBI-12654979	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:tkt_mycpn(display_long)|uniprotkb:tktA(gene name synonym)|uniprotkb:tkt(gene name)|psi-mi:tkt(display_short)|uniprotkb:MP073(orf name)|uniprotkb:MPN_082(locus name)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917917|imex:IM-25880-42	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0016020""(membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR033247|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR029061|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|refseq:NP_109770.1|refseq:WP_010874439.1"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:BhDXt/cNzav8lYxIgkE2jdHpa7c272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:D8C273EDAF0926AF	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78007	uniprotkb:P04004	intact:EBI-2260877	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:ldh_mycpn(display_long)|uniprotkb:MP168(orf name)|uniprotkb:MPN_674(locus name)|uniprotkb:ldh(gene name)|psi-mi:ldh(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917923|imex:IM-25880-44	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|refseq:NP_110363.1|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR018177|interpro:IPR022383|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|refseq:WP_010875031.1|interpro:IPR036291"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:dQR2ufgJU2G1Fa0OPl+ME9jTUDw272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:3950ED9A9F087E2B	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75392	uniprotkb:P02751	intact:EBI-2259593	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13917929|imex:IM-25880-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:217.47x10^-8 ~68.06(molar)	2016/12/15	2025/03/25	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:C1A2D726AC4E5B1E|rigid:pHZzlCbBSDNXH6XH8W80kMe25aE	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75358	uniprotkb:P02751	intact:EBI-2259469	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940086|imex:IM-25880-54	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/25	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:75139F9DB71B3AC8	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75358	uniprotkb:P02751	intact:EBI-2259469	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940393|imex:IM-25880-3	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:12.25x10^-8 ~6.51(molar)	2016/12/15	2025/03/25	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:2EEC9726AC4DB08D|rigid:QKEd4MPrgZ/fzcG3oXf3aW3oEgo	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75358	uniprotkb:P02751	intact:EBI-2259469	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940406|imex:IM-25880-46	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/25	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:F15E5793DF9AECA6	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75358	uniprotkb:P02788	intact:EBI-2259469	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940416|imex:IM-25880-23	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:17.4x10^-8(molar)	2016/12/15	2025/01/19	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:B6D0ECC54A8982A6|rigid:t3sO+X5xGnWXoP8ukZQgnyyjOjs	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75358	uniprotkb:P02788	intact:EBI-2259469	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940423|imex:IM-25880-56	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/01/19	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:F9ABE59603110E86	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75358	uniprotkb:P04004	intact:EBI-2259469	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940433|imex:IM-25880-25	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:13.69x10^-8 ~11.41(molar)	2016/12/15	2025/03/10	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:332A27E6B45CE829|rigid:wzrf0Z6NLuvrUlFSarbP7aPwjsY	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75358	uniprotkb:P04004	intact:EBI-2259469	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:g3p_mycpn(display_long)|uniprotkb:gap(gene name synonym)|uniprotkb:MP411(orf name)|uniprotkb:MPN_430(locus name)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940440|imex:IM-25880-72	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110118.1|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_010874786.1|interpro:IPR036291"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:3tc686G8zXP63ewM6cQvB2dbUXE272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:EC98E753C78BB402	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75167	uniprotkb:P04004	intact:EBI-2259565	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:gpmi_mycpn(display_long)|uniprotkb:pgm(gene name synonym)|uniprotkb:MP214(orf name)|uniprotkb:MPN_628(locus name)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940450|imex:IM-25880-58	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|refseq:NP_110317.1|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0030145""(manganese ion binding)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|go:""GO:0051919""(positive regulation of fibrinolysis)|refseq:WP_010874985.1|interpro:IPR036646"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:HrxbL8sfnlZRkDD3zllGqh7xdMg272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:613D85B3C789A91D	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78007	uniprotkb:P04004	intact:EBI-2260877	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:ldh_mycpn(display_long)|uniprotkb:MP168(orf name)|uniprotkb:MPN_674(locus name)|uniprotkb:ldh(gene name)|psi-mi:ldh(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940461|imex:IM-25880-5	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|refseq:NP_110363.1|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR018177|interpro:IPR022383|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|refseq:WP_010875031.1|interpro:IPR036291"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:313.78x10^-8 ~82.78(molar)	2016/12/15	2025/03/10	rogid:dQR2ufgJU2G1Fa0OPl+ME9jTUDw272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:62AFE521845EF46E|rigid:73U6KxrC3LyVgkQ9Dm0nAsKs3cc	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78007	uniprotkb:P04004	intact:EBI-2260877	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:ldh_mycpn(display_long)|uniprotkb:MP168(orf name)|uniprotkb:MPN_674(locus name)|uniprotkb:ldh(gene name)|psi-mi:ldh(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940468|imex:IM-25880-74	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|refseq:NP_110363.1|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR018177|interpro:IPR022383|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|refseq:WP_010875031.1|interpro:IPR036291"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:dQR2ufgJU2G1Fa0OPl+ME9jTUDw272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:BD1D2594F789A845	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75390	uniprotkb:P02788	intact:EBI-2259629	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940478|imex:IM-25880-27	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:8.15x10^-8 ~5.0(molar)	2016/12/15	2025/01/19	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:3B7EACC54A8AA16A|rigid:uZ91eGTc7wALg4RUuAXh22Vl/2M	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75390	uniprotkb:P02788	intact:EBI-2259629	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940485|imex:IM-25880-60	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/01/19	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:7405A59603122D4A	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75390	uniprotkb:P04004	intact:EBI-2259629	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940495|imex:IM-25880-11	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:14.5x10^-8 ~6.39(molar)	2016/12/15	2025/03/10	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:BE8467E6B45FCBE5|rigid:q/nptPA1zL0kKZXepe0Qr6FG59M	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75390	uniprotkb:P04004	intact:EBI-2259629	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:odpa_mycpn(display_long)|uniprotkb:MP445(orf name)|uniprotkb:MPN_393(locus name)|uniprotkb:pdhA(gene name)|psi-mi:pdhA(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940502|imex:IM-25880-76	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017596(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x"")|refseq:NP_110081.1|refseq:WP_010874749.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|interpro:IPR050771|interpro:IPR029061"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:655K9tZF+AAVXrnx4c+DW9RtnkQ272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:6136A753C78897CE	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P02788	intact:EBI-2259621	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940512|imex:IM-25880-13	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:20.6x10^-8 ~7.18(molar)	2016/12/15	2025/01/19	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:D20EACC54A8AC545|rigid:XRVapZ3mq9sRZW2pF4Sf9yrV2Lg	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P02788	intact:EBI-2259621	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940519|imex:IM-25880-78	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/01/19	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:9D75A59603124965	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P04004	intact:EBI-2259621	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940529|imex:IM-25880-7	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:12.43x10^-8 ~4.63(molar)	2016/12/15	2025/03/10	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:57F467E6B45FAFCA|rigid:duTd+AeL2sh13Wy6/EmUrWgvFEI	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P04004	intact:EBI-2259621	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940536|imex:IM-25880-80	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:8846A753C788F3E1	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75392	uniprotkb:P02751	intact:EBI-2259593	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940549|imex:IM-25880-62	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/25	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:1E101793DF990735	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75392	uniprotkb:P02788	intact:EBI-2259593	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940559|imex:IM-25880-15	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:236.13x10^-8 ~119.43(molar)	2016/12/15	2025/01/19	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:599EACC54A8A6935|rigid:vmlucF24V2bfvh2HilmejTbsm5M	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75392	uniprotkb:P02788	intact:EBI-2259593	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:odp2_mycpn(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:MP447(orf name)|uniprotkb:MPN_391(locus name)|uniprotkb:pdhC(gene name)|psi-mi:pdhC(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940566|imex:IM-25880-64	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|refseq:NP_110079.1|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031405""(lipoic acid binding)|interpro:IPR023213|interpro:IPR050743|refseq:WP_010874747.1"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/01/19	rogid:NknqgO3hQzH7ODEPqRBX3J9wnSU272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:16E5A5960312E515	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78031	uniprotkb:P02788	intact:EBI-2259473	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:kpyk_mycpn(display_long)|uniprotkb:MP533(orf name)|uniprotkb:MPN_303(locus name)|uniprotkb:pyk(gene name)|psi-mi:pyk(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940578|imex:IM-25880-9	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_109991.1|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031639""(plasminogen activation)|refseq:WP_010874660.1|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:22.38x10^-8 ~11.7(molar)	2016/12/15	2025/01/19	rogid:ovUfpbDSZQd3WYZ9w4bChqq6oR4272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:01FEBE027A8AC6AC|rigid:lCDfnJY2nWGjH9Jfua45QMg2B5U	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78031	uniprotkb:P02788	intact:EBI-2259473	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:kpyk_mycpn(display_long)|uniprotkb:MP533(orf name)|uniprotkb:MPN_303(locus name)|uniprotkb:pyk(gene name)|psi-mi:pyk(display_short)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940585|imex:IM-25880-48	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_109991.1|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031639""(plasminogen activation)|refseq:WP_010874660.1|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/01/19	rogid:ovUfpbDSZQd3WYZ9w4bChqq6oR4272634	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:4E85B75133124A8C	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78031	uniprotkb:P04004	intact:EBI-2259473	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:kpyk_mycpn(display_long)|uniprotkb:MP533(orf name)|uniprotkb:MPN_303(locus name)|uniprotkb:pyk(gene name)|psi-mi:pyk(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940595|imex:IM-25880-29	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_109991.1|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031639""(plasminogen activation)|refseq:WP_010874660.1|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.46x10^-8 ~1.77(molar)	2016/12/15	2025/03/10	rogid:ovUfpbDSZQd3WYZ9w4bChqq6oR4272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:84047521845FAC23|rigid:A+MOpQ0jMe7onY7kse7y1V3ZtWM	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P78031	uniprotkb:P04004	intact:EBI-2259473	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:kpyk_mycpn(display_long)|uniprotkb:MP533(orf name)|uniprotkb:MPN_303(locus name)|uniprotkb:pyk(gene name)|psi-mi:pyk(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940602|imex:IM-25880-66	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_109991.1|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031639""(plasminogen activation)|refseq:WP_010874660.1|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:ovUfpbDSZQd3WYZ9w4bChqq6oR4272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:5BB6B594F788F008	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75611	uniprotkb:P04004	intact:EBI-12654979	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:tkt_mycpn(display_long)|uniprotkb:tktA(gene name synonym)|uniprotkb:tkt(gene name)|psi-mi:tkt(display_short)|uniprotkb:MP073(orf name)|uniprotkb:MPN_082(locus name)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940612|imex:IM-25880-17	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0016020""(membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR033247|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR029061|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|refseq:NP_109770.1|refseq:WP_010874439.1"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:11.44x10^-8 ~4.9(molar)	2016/12/15	2025/03/10	rogid:BhDXt/cNzav8lYxIgkE2jdHpa7c272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:833D7B56B45FACEA|rigid:caS/QooJXknNOkM8TJWRaoOh1nk	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75611	uniprotkb:P04004	intact:EBI-12654979	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:tkt_mycpn(display_long)|uniprotkb:tktA(gene name synonym)|uniprotkb:tkt(gene name)|psi-mi:tkt(display_short)|uniprotkb:MP073(orf name)|uniprotkb:MPN_082(locus name)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Gründel et al. (2016)	pubmed:27616280|imex:IM-25880	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13940620|imex:IM-25880-68	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0016020""(membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR033247|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR029061|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|refseq:NP_109770.1|refseq:WP_010874439.1"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:fig 3&4, table 1&2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2025/03/10	rogid:BhDXt/cNzav8lYxIgkE2jdHpa7c272634	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:5C8FBBE3C788F0C1	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P18428	uniprotkb:Q9R3N6	intact:EBI-3927059|uniprotkb:B2R938|uniprotkb:Q9UD66|uniprotkb:O43438|uniprotkb:Q9H403|uniprotkb:Q92672|ensembl:ENSP00000217407.2	intact:EBI-12736182	psi-mi:lbp_human(display_long)|uniprotkb:LBP(gene name)|psi-mi:LBP(display_short)	psi-mi:q9r3n6_mycfe(display_long)|uniprotkb:malP(gene name)|psi-mi:malP(display_short)|uniprotkb:malp(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Schröder et al. (2004)	pubmed:15294986|imex:IM-25869	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2115(Mycoplasma fermentans)|taxid:2115(Mycoplasma fermentans)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12736178|imex:IM-25869-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004130.2|ensembl:ENSG00000129988.6(gene)|ensembl:ENST00000217407.3(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002232""(leukocyte chemotaxis involved in inflammatory response)|go:""GO:0002281""(macrophage activation involved in immune response)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0006953""(acute-phase response)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006968""(cellular defense response)|go:""GO:0008228""(opsonization)|go:""GO:0009986""(cell surface)|go:""GO:0015026""(coreceptor activity)|go:""GO:0015920""(lipopolysaccharide transport)|go:""GO:0016020""(membrane)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032490""(detection of molecule of bacterial origin)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0043032""(positive regulation of macrophage activation)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0060265""(positive regulation of respiratory burst involved in inflammatory response)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070891""(lipoteichoic acid binding)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071723""(lipopeptide binding)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|interpro:IPR001124(Lipid-binding serum glycoprotein)|interpro:IPR017942|interpro:IPR017943|interpro:IPR017954|interpro:IPR030675|interpro:IPR032942|reactome:R-HSA-166016|reactome:R-HSA-166020|reactome:R-HSA-5686938|reactome:R-HSA-6785807|dip:DIP-90N|panther:PTHR10504(orthology-group)"	"interpro:IPR049890|interpro:IPR008107(Mycoplasma P48 major surface lipoprotein)|interpro:IPR003760(Basic membrane lipoprotein)|go:""GO:0005886""(plasma membrane)|interpro:IPR050957"	-	-	-	figure legend:5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2024/11/14	rogid:dSU+dnC7sUIeRc5ff52LhvrF58o9606	rogid:Z0ZmItXp/69B7YMbOl+4i/ENOP42115	intact-crc:823EB9250AE819F9|rigid:3byGzGmsRJcB8/xR/dWm1ixHjAw	false	-	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P00747	intact:EBI-2259621	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Thomas et al. (2013)	pubmed:23197176|imex:IM-25872	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12737077|imex:IM-25872-3	intact-miscore:0.83	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2024/11/14	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:3E1B6DC81863CD1C|rigid:rbpPnM94cb3alyoiXVn/sGuf2U8	false	-	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75189	uniprotkb:P00747	intact:EBI-2259492|uniprotkb:Q50324	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:eno_mycpn(display_long)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:MP236(orf name)|uniprotkb:MPN_606(locus name)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Thomas et al. (2013)	pubmed:23197176|imex:IM-25872	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12737081|imex:IM-25872-5	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110295.1|interpro:IPR000941(Enolase)|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0006096""(glycolytic process)|go:""GO:0009986""(cell surface)|refseq:WP_010874963.1|interpro:IPR029017|interpro:IPR036849|rcsb pdb:7E2Q"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2024/11/14	rogid:etBzx133hDDDVpv1soImrVSmai0272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:04673850D98BBB74|rigid:b05CeIS/l+TWt1YWSRmwoFZFGk8	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P00747	intact:EBI-2259621	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Thomas et al. (2013)	pubmed:23197176|imex:IM-25872	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12737085|imex:IM-25872-7	intact-miscore:0.83	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:6D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2024/11/14	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:5941DD61FAC2F16E|rigid:rbpPnM94cb3alyoiXVn/sGuf2U8	false	necessary binding region:91-102	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P00747	uniprotkb:P75391	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-2259621	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Thomas et al. (2013)	pubmed:23197176|imex:IM-25872	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13916758|imex:IM-25872-11	intact-miscore:0.83	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	-	-	-	figure legend:5B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	intact-crc:CFC86E14802F7F70|rigid:rbpPnM94cb3alyoiXVn/sGuf2U8	false	-	his tag:n-n	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P00747	intact:EBI-2259621	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0047""(far western blotting)"	Thomas et al. (2013)	pubmed:23197176|imex:IM-25872	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12737098|imex:IM-25872-9	intact-miscore:0.83	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:6B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2024/11/14	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:81999C6ACDDD1935|rigid:rbpPnM94cb3alyoiXVn/sGuf2U8	false	his tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P75391	uniprotkb:P00747	intact:EBI-2259621	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0049""(filter binding)"	Thomas et al. (2013)	pubmed:23197176|imex:IM-25872	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12737058|imex:IM-25872-1	intact-miscore:0.83	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:6C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2024/11/14	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:EF7B4A03F0AF24A3|rigid:rbpPnM94cb3alyoiXVn/sGuf2U8	false	his tag:n-n	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P75391	uniprotkb:P00747	intact:EBI-2259621	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:odpb_mycpn(display_long)|uniprotkb:MP446(orf name)|uniprotkb:MPN_392(locus name)|uniprotkb:pdhB(gene name)|psi-mi:pdhB(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0049""(filter binding)"	Thomas et al. (2013)	pubmed:23197176|imex:IM-25872	"taxid:272634(mycpn)|taxid:272634(""Mycoplasma pneumoniae (strain ATCC 29342 / M129)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13916772|imex:IM-25872-13	intact-miscore:0.83	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0031639""(plasminogen activation)|go:""GO:0033111""(attachment organelle membrane)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|refseq:NP_110080.1|go:""GO:0001968""(fibronectin binding)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|refseq:WP_010874748.1|go:""GO:0051919""(positive regulation of fibrinolysis)|interpro:IPR033248|interpro:IPR029061"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	-	-	-	figure legend:6C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/12/15	2024/11/14	rogid:hU4qrc4C+9SyR/BH++rWpXFWx44272634	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:17DBDDB6D696FB94|rigid:rbpPnM94cb3alyoiXVn/sGuf2U8	false	his tag:n-n|necessary binding region:91-102	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q98PK8	uniprotkb:P40763	intact:EBI-12740386	intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|uniprotkb:A8K7B8|uniprotkb:K7ENL3|ensembl:ENSP00000264657.4|ensembl:ENSP00000467985.1|ensembl:ENSP00000503102.1|ensembl:ENSP00000503181.1|ensembl:ENSP00000504184.1|ensembl:ENSP00000520412.1	psi-mi:q98pk8_mycpu(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:MYPU_7140(locus name)	psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Hu et al. (2014)	pubmed:24172987|imex:IM-25870	"taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")|taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740383|imex:IM-25870-1	intact-miscore:0.51	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_010925515.1|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR024704|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030261""(chromosome condensation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:1902745""(positive regulation of lamellipodium organization)|interpro:IPR036277"	"efo:""Orphanet:2314""|efo:""Orphanet:438159""|efo:""Orphanet:512017""|efo:""Orphanet:520""|efo:""Orphanet:86872""|efo:""Orphanet:99885""|efo:""Orphanet:667662""|ensembl:ENSG00000168610.17(gene)|ensembl:ENST00000264657.10(transcript)|ensembl:ENST00000588969.5(transcript)|ensembl:ENST00000678044.1(transcript)|ensembl:ENST00000678906.1(transcript)|ensembl:ENST00000678960.1(transcript)|ensembl:ENST00000715205.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001659""(temperature homeostasis)|go:""GO:0001754""(eye photoreceptor cell differentiation)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004879""(nuclear receptor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0007399""(nervous system development)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016310""(phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019953""(sexual reproduction)|go:""GO:0030154""(cell differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030522""(intracellular receptor signaling pathway)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0033210""(leptin-mediated signaling pathway)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038155""(interleukin-23-mediated signaling pathway)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042755""(eating behavior)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0044320""(cellular response to leptin stimulus)|go:""GO:0044321""(response to leptin)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045820""(negative regulation of glycolytic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060019""(radial glial cell differentiation)|go:""GO:0060221""(retinal rod cell differentiation)|go:""GO:0060259""(regulation of feeding behavior)|go:""GO:0060396""(growth hormone receptor signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0070878""(primary miRNA binding)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0097009""(energy homeostasis)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0097696""(cell surface receptor signaling pathway via STAT)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0106222""(lncRNA binding)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140610""(RNA sequestering activity)|go:""GO:1900017""(positive regulation of cytokine production involved in inflammatory response)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904685""(positive regulation of metalloendopeptidase activity)|go:""GO:1905564""(positive regulation of vascular endothelial cell proliferation)|go:""GO:2000635""(negative regulation of primary miRNA processing)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2001223""(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|interpro:IPR048988|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-201556|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9701898|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-9833482|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N|panther:PTHR11801(orthology-group)|ensembl:ENSP00000264657.4|ensembl:ENST00000404395.3|ensembl:ENSP00000384943.3|ensembl:ENST00000585517.5|ensembl:ENSP00000467000.1|ensembl:ENSP00000467985.1|ensembl:ENST00000677030.1|ensembl:ENSP00000503662.1|ensembl:ENST00000677723.1|ensembl:ENSP00000503574.1|ensembl:ENSP00000503102.1|ensembl:ENST00000678827.1|ensembl:ENSP00000503634.1|ensembl:ENSP00000504184.1|ensembl:ENSP00000503181.1|ensembl:ENST00000679014.1|ensembl:ENSP00000503237.1|ensembl:ENSP00000520412.1"	-	-	crc64:6C00632211C8012D	figure legend:2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2016/12/15	2025/02/28	rogid:64hx+YH6Xjsvcp7PMLq3bl8AbQk272635	rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606	intact-crc:D92CED467D6958F5|rigid:VNqX9Ymbg7pf6Xkm6X4NFU0zx0M	false	glutathione s tranferase tag:n-n|sufficient binding region:9-248	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q98PK8	uniprotkb:P63000	intact:EBI-12740386	intact:EBI-413628|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q9BTB4|uniprotkb:Q5JAA8|ensembl:ENSP00000258737.7	psi-mi:q98pk8_mycpu(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:MYPU_7140(locus name)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Hu et al. (2014)	pubmed:24172987|imex:IM-25870	"taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")|taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740383|imex:IM-25870-1	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_010925515.1|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR024704|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030261""(chromosome condensation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:1902745""(positive regulation of lamellipodium organization)|interpro:IPR036277"	"efo:""Orphanet:500159""|ensembl:ENSG00000136238.20(gene)|ensembl:ENST00000348035.9(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006954""(inflammatory response)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009611""(response to wounding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031529""(ruffle organization)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032707""(negative regulation of interleukin-23 production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042470""(melanosome)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045428""(regulation of nitric oxide biosynthetic process)|go:""GO:0045730""(respiratory burst)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048870""(cell motility)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051668""(localization within membrane)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060263""(regulation of respiratory burst)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0097178""(ruffle assembly)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902622""(regulation of neutrophil migration)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:7DPA|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|rcsb pdb:7SJ4|rcsb pdb:7USD|rcsb pdb:7USE|rcsb pdb:8I5V|rcsb pdb:8I5W|rcsb pdb:8Q0N|rcsb pdb:8WEJ|rcsb pdb:8ZJ2|rcsb pdb:8ZJI|rcsb pdb:8ZJJ|rcsb pdb:8ZJK|rcsb pdb:8ZJL|rcsb pdb:8ZJM|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-9748787|reactome:R-HSA-983231|refseq:NP_008839.2|refseq:NP_061485.1|dip:DIP-29260N|panther:PTHR24072(orthology-group)|ensembl:ENSP00000258737.7|ensembl:ENST00000356142.4|ensembl:ENSP00000348461.4"	-	-	-	figure legend:2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2016/12/15	2025/02/28	rogid:64hx+YH6Xjsvcp7PMLq3bl8AbQk272635	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:D92CED467D6958F5|rigid:VNqX9Ymbg7pf6Xkm6X4NFU0zx0M	false	glutathione s tranferase tag:n-n|sufficient binding region:9-248	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q98PK8	uniprotkb:P40763	intact:EBI-12740386	intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|uniprotkb:A8K7B8|uniprotkb:K7ENL3|ensembl:ENSP00000264657.4|ensembl:ENSP00000467985.1|ensembl:ENSP00000503102.1|ensembl:ENSP00000503181.1|ensembl:ENSP00000504184.1|ensembl:ENSP00000520412.1	psi-mi:q98pk8_mycpu(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:MYPU_7140(locus name)	psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Hu et al. (2014)	pubmed:24172987|imex:IM-25870	"taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")|taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740449|imex:IM-25870-3	intact-miscore:0.51	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_010925515.1|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR024704|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030261""(chromosome condensation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:1902745""(positive regulation of lamellipodium organization)|interpro:IPR036277"	"efo:""Orphanet:2314""|efo:""Orphanet:438159""|efo:""Orphanet:512017""|efo:""Orphanet:520""|efo:""Orphanet:86872""|efo:""Orphanet:99885""|efo:""Orphanet:667662""|ensembl:ENSG00000168610.17(gene)|ensembl:ENST00000264657.10(transcript)|ensembl:ENST00000588969.5(transcript)|ensembl:ENST00000678044.1(transcript)|ensembl:ENST00000678906.1(transcript)|ensembl:ENST00000678960.1(transcript)|ensembl:ENST00000715205.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001659""(temperature homeostasis)|go:""GO:0001754""(eye photoreceptor cell differentiation)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004879""(nuclear receptor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0007399""(nervous system development)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016310""(phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019953""(sexual reproduction)|go:""GO:0030154""(cell differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030522""(intracellular receptor signaling pathway)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0033210""(leptin-mediated signaling pathway)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038155""(interleukin-23-mediated signaling pathway)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042755""(eating behavior)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0044320""(cellular response to leptin stimulus)|go:""GO:0044321""(response to leptin)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045820""(negative regulation of glycolytic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060019""(radial glial cell differentiation)|go:""GO:0060221""(retinal rod cell differentiation)|go:""GO:0060259""(regulation of feeding behavior)|go:""GO:0060396""(growth hormone receptor signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0070878""(primary miRNA binding)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0097009""(energy homeostasis)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0097696""(cell surface receptor signaling pathway via STAT)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0106222""(lncRNA binding)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140610""(RNA sequestering activity)|go:""GO:1900017""(positive regulation of cytokine production involved in inflammatory response)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904685""(positive regulation of metalloendopeptidase activity)|go:""GO:1905564""(positive regulation of vascular endothelial cell proliferation)|go:""GO:2000635""(negative regulation of primary miRNA processing)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2001223""(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|interpro:IPR048988|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-201556|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9701898|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-9833482|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N|panther:PTHR11801(orthology-group)|ensembl:ENSP00000264657.4|ensembl:ENST00000404395.3|ensembl:ENSP00000384943.3|ensembl:ENST00000585517.5|ensembl:ENSP00000467000.1|ensembl:ENSP00000467985.1|ensembl:ENST00000677030.1|ensembl:ENSP00000503662.1|ensembl:ENST00000677723.1|ensembl:ENSP00000503574.1|ensembl:ENSP00000503102.1|ensembl:ENST00000678827.1|ensembl:ENSP00000503634.1|ensembl:ENSP00000504184.1|ensembl:ENSP00000503181.1|ensembl:ENST00000679014.1|ensembl:ENSP00000503237.1|ensembl:ENSP00000520412.1"	-	-	crc64:6C00632211C8012D	figure legend:2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2016/12/15	2025/02/28	rogid:64hx+YH6Xjsvcp7PMLq3bl8AbQk272635	rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606	intact-crc:2351F25594F860AD|rigid:VNqX9Ymbg7pf6Xkm6X4NFU0zx0M	false	green fluorescent protein tag:n-n|sufficient binding region:9-248	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q98PK8	uniprotkb:P63000	intact:EBI-12740386	intact:EBI-413628|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q9BTB4|uniprotkb:Q5JAA8|ensembl:ENSP00000258737.7	psi-mi:q98pk8_mycpu(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:MYPU_7140(locus name)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Hu et al. (2014)	pubmed:24172987|imex:IM-25870	"taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")|taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740449|imex:IM-25870-3	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_010925515.1|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR024704|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030261""(chromosome condensation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:1902745""(positive regulation of lamellipodium organization)|interpro:IPR036277"	"efo:""Orphanet:500159""|ensembl:ENSG00000136238.20(gene)|ensembl:ENST00000348035.9(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006954""(inflammatory response)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009611""(response to wounding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031529""(ruffle organization)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032707""(negative regulation of interleukin-23 production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042470""(melanosome)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045428""(regulation of nitric oxide biosynthetic process)|go:""GO:0045730""(respiratory burst)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048870""(cell motility)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051668""(localization within membrane)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060263""(regulation of respiratory burst)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0097178""(ruffle assembly)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902622""(regulation of neutrophil migration)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:7DPA|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|rcsb pdb:7SJ4|rcsb pdb:7USD|rcsb pdb:7USE|rcsb pdb:8I5V|rcsb pdb:8I5W|rcsb pdb:8Q0N|rcsb pdb:8WEJ|rcsb pdb:8ZJ2|rcsb pdb:8ZJI|rcsb pdb:8ZJJ|rcsb pdb:8ZJK|rcsb pdb:8ZJL|rcsb pdb:8ZJM|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-9748787|reactome:R-HSA-983231|refseq:NP_008839.2|refseq:NP_061485.1|dip:DIP-29260N|panther:PTHR24072(orthology-group)|ensembl:ENSP00000258737.7|ensembl:ENST00000356142.4|ensembl:ENSP00000348461.4"	-	-	-	figure legend:2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2016/12/15	2025/02/28	rogid:64hx+YH6Xjsvcp7PMLq3bl8AbQk272635	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:2351F25594F860AD|rigid:VNqX9Ymbg7pf6Xkm6X4NFU0zx0M	false	green fluorescent protein tag:n-n|sufficient binding region:9-248	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q98PK8	uniprotkb:P40763	intact:EBI-12740386	intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|uniprotkb:A8K7B8|uniprotkb:K7ENL3|ensembl:ENSP00000264657.4|ensembl:ENSP00000467985.1|ensembl:ENSP00000503102.1|ensembl:ENSP00000503181.1|ensembl:ENSP00000504184.1|ensembl:ENSP00000520412.1	psi-mi:q98pk8_mycpu(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:MYPU_7140(locus name)	psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Hu et al. (2014)	pubmed:24172987|imex:IM-25870	"taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")|taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740612|imex:IM-25870-5	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_010925515.1|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR024704|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030261""(chromosome condensation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:1902745""(positive regulation of lamellipodium organization)|interpro:IPR036277"	"efo:""Orphanet:2314""|efo:""Orphanet:438159""|efo:""Orphanet:512017""|efo:""Orphanet:520""|efo:""Orphanet:86872""|efo:""Orphanet:99885""|efo:""Orphanet:667662""|ensembl:ENSG00000168610.17(gene)|ensembl:ENST00000264657.10(transcript)|ensembl:ENST00000588969.5(transcript)|ensembl:ENST00000678044.1(transcript)|ensembl:ENST00000678906.1(transcript)|ensembl:ENST00000678960.1(transcript)|ensembl:ENST00000715205.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001659""(temperature homeostasis)|go:""GO:0001754""(eye photoreceptor cell differentiation)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004879""(nuclear receptor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0007399""(nervous system development)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016310""(phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019953""(sexual reproduction)|go:""GO:0030154""(cell differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030522""(intracellular receptor signaling pathway)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0033210""(leptin-mediated signaling pathway)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038155""(interleukin-23-mediated signaling pathway)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042755""(eating behavior)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0044320""(cellular response to leptin stimulus)|go:""GO:0044321""(response to leptin)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045820""(negative regulation of glycolytic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060019""(radial glial cell differentiation)|go:""GO:0060221""(retinal rod cell differentiation)|go:""GO:0060259""(regulation of feeding behavior)|go:""GO:0060396""(growth hormone receptor signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0070878""(primary miRNA binding)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0097009""(energy homeostasis)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0097696""(cell surface receptor signaling pathway via STAT)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0106222""(lncRNA binding)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140610""(RNA sequestering activity)|go:""GO:1900017""(positive regulation of cytokine production involved in inflammatory response)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904685""(positive regulation of metalloendopeptidase activity)|go:""GO:1905564""(positive regulation of vascular endothelial cell proliferation)|go:""GO:2000635""(negative regulation of primary miRNA processing)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2001223""(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|interpro:IPR048988|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-201556|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9701898|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-9833482|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N|panther:PTHR11801(orthology-group)|ensembl:ENSP00000264657.4|ensembl:ENST00000404395.3|ensembl:ENSP00000384943.3|ensembl:ENST00000585517.5|ensembl:ENSP00000467000.1|ensembl:ENSP00000467985.1|ensembl:ENST00000677030.1|ensembl:ENSP00000503662.1|ensembl:ENST00000677723.1|ensembl:ENSP00000503574.1|ensembl:ENSP00000503102.1|ensembl:ENST00000678827.1|ensembl:ENSP00000503634.1|ensembl:ENSP00000504184.1|ensembl:ENSP00000503181.1|ensembl:ENST00000679014.1|ensembl:ENSP00000503237.1|ensembl:ENSP00000520412.1"	"go:""GO:0005737""(cytoplasm)|go:""GO:0005634""(nucleus)"	-	crc64:6C00632211C8012D	figure legend:2C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2016/12/15	2025/02/28	rogid:64hx+YH6Xjsvcp7PMLq3bl8AbQk272635	rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606	intact-crc:2F9828948BE48F13|rigid:qV6dkrLzRFBaRJ2QCvixppxiRxk	false	binding-associated region:9-248|flag tag:?-?	-	-	-	"psi-mi:""MI:1200""(immunocytochemistry)"	"psi-mi:""MI:1200""(immunocytochemistry)"
uniprotkb:Q98PK8	uniprotkb:P63000	intact:EBI-12740386	intact:EBI-413628|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q9BTB4|uniprotkb:Q5JAA8|ensembl:ENSP00000258737.7	psi-mi:q98pk8_mycpu(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:MYPU_7140(locus name)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	"psi-mi:""MI:0055""(fluorescent resonance energy transfer)"	Hu et al. (2014)	pubmed:24172987|imex:IM-25870	"taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")|taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740649|imex:IM-25870-7	intact-miscore:0.61	-	"psi-mi:""MI:0918""(donor)"	"psi-mi:""MI:0919""(acceptor)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_010925515.1|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR024704|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030261""(chromosome condensation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:1902745""(positive regulation of lamellipodium organization)|interpro:IPR036277"	"efo:""Orphanet:500159""|ensembl:ENSG00000136238.20(gene)|ensembl:ENST00000348035.9(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006954""(inflammatory response)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009611""(response to wounding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031529""(ruffle organization)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032707""(negative regulation of interleukin-23 production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042470""(melanosome)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045428""(regulation of nitric oxide biosynthetic process)|go:""GO:0045730""(respiratory burst)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048870""(cell motility)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051668""(localization within membrane)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060263""(regulation of respiratory burst)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0097178""(ruffle assembly)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902622""(regulation of neutrophil migration)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:7DPA|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|rcsb pdb:7SJ4|rcsb pdb:7USD|rcsb pdb:7USE|rcsb pdb:8I5V|rcsb pdb:8I5W|rcsb pdb:8Q0N|rcsb pdb:8WEJ|rcsb pdb:8ZJ2|rcsb pdb:8ZJI|rcsb pdb:8ZJJ|rcsb pdb:8ZJK|rcsb pdb:8ZJL|rcsb pdb:8ZJM|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-9748787|reactome:R-HSA-983231|refseq:NP_008839.2|refseq:NP_061485.1|dip:DIP-29260N|panther:PTHR24072(orthology-group)|ensembl:ENSP00000258737.7|ensembl:ENST00000356142.4|ensembl:ENSP00000348461.4"	-	-	-	figure legend:2D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2016/12/15	2024/11/14	rogid:64hx+YH6Xjsvcp7PMLq3bl8AbQk272635	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:404A54E14A3CCDAC|rigid:rapQ1PSmh88YmRkG2LlJuauYlDM	false	green fluorescent protein tag:n-n|sufficient binding region:9-248	red fluorescent protein tag:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P63000	uniprotkb:Q98PK8	intact:EBI-413628|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q9BTB4|uniprotkb:Q5JAA8|ensembl:ENSP00000258737.7	intact:EBI-12740386	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	psi-mi:q98pk8_mycpu(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:MYPU_7140(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Hu et al. (2014)	pubmed:24172987|imex:IM-25870	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")|taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13915252|imex:IM-25870-9	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:500159""|ensembl:ENSG00000136238.20(gene)|ensembl:ENST00000348035.9(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006954""(inflammatory response)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009611""(response to wounding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031529""(ruffle organization)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032707""(negative regulation of interleukin-23 production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042470""(melanosome)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045428""(regulation of nitric oxide biosynthetic process)|go:""GO:0045730""(respiratory burst)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048870""(cell motility)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051668""(localization within membrane)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060263""(regulation of respiratory burst)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0097178""(ruffle assembly)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902622""(regulation of neutrophil migration)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:7DPA|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|rcsb pdb:7SJ4|rcsb pdb:7USD|rcsb pdb:7USE|rcsb pdb:8I5V|rcsb pdb:8I5W|rcsb pdb:8Q0N|rcsb pdb:8WEJ|rcsb pdb:8ZJ2|rcsb pdb:8ZJI|rcsb pdb:8ZJJ|rcsb pdb:8ZJK|rcsb pdb:8ZJL|rcsb pdb:8ZJM|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-9748787|reactome:R-HSA-983231|refseq:NP_008839.2|refseq:NP_061485.1|dip:DIP-29260N|panther:PTHR24072(orthology-group)|ensembl:ENSP00000258737.7|ensembl:ENST00000356142.4|ensembl:ENSP00000348461.4"	"refseq:WP_010925515.1|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR024704|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030261""(chromosome condensation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:1902745""(positive regulation of lamellipodium organization)|interpro:IPR036277"	-	-	-	figure legend:2D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2016/12/15	2024/11/14	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	rogid:64hx+YH6Xjsvcp7PMLq3bl8AbQk272635	intact-crc:128F29057E9D87CF|rigid:rapQ1PSmh88YmRkG2LlJuauYlDM	false	red fluorescent protein tag:?-?	sufficient binding region:9-248|green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q98PK8	uniprotkb:P63000	intact:EBI-12740386	intact:EBI-413628|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q9BTB4|uniprotkb:Q5JAA8|ensembl:ENSP00000258737.7	psi-mi:q98pk8_mycpu(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:MYPU_7140(locus name)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	"psi-mi:""MI:1016""(fluorescence recovery after photobleaching)"	Hu et al. (2014)	pubmed:24172987|imex:IM-25870	"taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")|taxid:272635(""Mycoplasma pulmonis (strain UAB CTIP)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-13915279|imex:IM-25870-11	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_010925515.1|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR024704|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030261""(chromosome condensation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:1902745""(positive regulation of lamellipodium organization)|interpro:IPR036277"	"efo:""Orphanet:500159""|ensembl:ENSG00000136238.20(gene)|ensembl:ENST00000348035.9(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006954""(inflammatory response)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009611""(response to wounding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031529""(ruffle organization)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032707""(negative regulation of interleukin-23 production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042470""(melanosome)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045428""(regulation of nitric oxide biosynthetic process)|go:""GO:0045730""(respiratory burst)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048870""(cell motility)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051668""(localization within membrane)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060263""(regulation of respiratory burst)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0097178""(ruffle assembly)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902622""(regulation of neutrophil migration)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:7DPA|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|rcsb pdb:7SJ4|rcsb pdb:7USD|rcsb pdb:7USE|rcsb pdb:8I5V|rcsb pdb:8I5W|rcsb pdb:8Q0N|rcsb pdb:8WEJ|rcsb pdb:8ZJ2|rcsb pdb:8ZJI|rcsb pdb:8ZJJ|rcsb pdb:8ZJK|rcsb pdb:8ZJL|rcsb pdb:8ZJM|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-9748787|reactome:R-HSA-983231|refseq:NP_008839.2|refseq:NP_061485.1|dip:DIP-29260N|panther:PTHR24072(orthology-group)|ensembl:ENSP00000258737.7|ensembl:ENST00000356142.4|ensembl:ENSP00000348461.4"	-	-	-	figure legend:2 E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2016/12/15	2024/11/14	rogid:64hx+YH6Xjsvcp7PMLq3bl8AbQk272635	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:BFA1F728E390ADF1|rigid:rapQ1PSmh88YmRkG2LlJuauYlDM	false	green fluorescent protein tag:n-n|sufficient binding region:9-248	red fluorescent protein tag:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P15363	uniprotkb:P07355	intact:EBI-12740262	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	psi-mi:p37_meshy(display_long)|uniprotkb:p37(gene name)|psi-mi:p37(display_short)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Yuan et al. (2015)	pubmed:26812398|imex:IM-25958	taxid:2100(Mycoplasma hyorhinis)|taxid:2100(Mycoplasma hyorhinis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12740259|imex:IM-25958-1	intact-miscore:0.78	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3E78|rcsb pdb:3E79|rcsb pdb:3EKI|interpro:IPR010592(High affinity transport system p37)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0005886""(plasma membrane)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR043099|interpro:IPR043100"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:1B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/18	2024/11/14	rogid:lpG8nJF4K6Ih8wXjJSz2bM0PXg02100	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	intact-crc:564F98F679A45931|rigid:E8OhEOjM1l1W8Hbp0XnyEkgR9/0	false	glutathione s tranferase tag:?-?	binding-associated region:1-30|biotin tag:?-?	-	-	"psi-mi:""MI:0981""(tag visualisation by peroxidase activity)"	"psi-mi:""MI:0981""(tag visualisation by peroxidase activity)"
uniprotkb:A0A024A2C9	uniprotkb:P04004	intact:EBI-12498321	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:a0a024a2c9_haeif(display_long)|uniprotkb:lph(gene name)|psi-mi:lph(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Al-Jubair et al. (2015)	pubmed:26538390|imex:IM-25995	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12498319|imex:IM-25995-18	intact-miscore:0.60	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_021034796.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR001677(Transferrin binding protein)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0009986""(cell surface)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0052562""(symbiont-mediated suppression of host immune response)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR054843"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:3B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/02	2025/03/10	rogid:5Q8KhV90bDSBMn6J93XWEagP4LQ727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:4772A53047A0FC35	false	binding-associated region:30-280	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:A0A024A2C9	uniprotkb:P08603	intact:EBI-12498321	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	psi-mi:a0a024a2c9_haeif(display_long)|uniprotkb:lph(gene name)|psi-mi:lph(display_short)	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Al-Jubair et al. (2015)	pubmed:26538390|imex:IM-25995	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12498335|imex:IM-25995-1	intact-miscore:0.71	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_021034796.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR001677(Transferrin binding protein)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0009986""(cell surface)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0052562""(symbiont-mediated suppression of host immune response)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR054843"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	-	-	-	figure legend:1A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/02	2025/01/22	rogid:5Q8KhV90bDSBMn6J93XWEagP4LQ727	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	intact-crc:9F25EBB61EAA0B55|rigid:/2t2pVAayAtJNVOwgvWTeCpDddk	false	binding-associated region:30-280|his tag:?-?	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:A4NBN9	uniprotkb:P04004	intact:EBI-12498346	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:hpe_haei3(display_long)|uniprotkb:pe(gene name)|psi-mi:pe(display_short)|uniprotkb:CGSHi3655_04936(orf name)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Al-Jubair et al. (2015)	pubmed:26538390|imex:IM-25995	"taxid:375177(""Haemophilus influenzae (strain NTHi 3655)"")|taxid:375177(""Haemophilus influenzae (strain NTHi 3655)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12498341|imex:IM-25995-3	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR043088|refseq:WP_005658162.1|rcsb pdb:3ZH5|rcsb pdb:3ZH6|rcsb pdb:3ZH7|interpro:IPR031939|interpro:IPR016595(Periplasmic protein, HI0178, predicted)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/02	2025/03/10	rogid:O6B3TbQyQeGdDba3Ny15EfcUyvU375177	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:C66CFDF4B82A49AC|rigid:OiIlVdbOh7WgI6X0R8Iafr9QKd4	false	-	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:A0A024A2C9	uniprotkb:P04004	intact:EBI-12498321	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:a0a024a2c9_haeif(display_long)|uniprotkb:lph(gene name)|psi-mi:lph(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Al-Jubair et al. (2015)	pubmed:26538390|imex:IM-25995	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12498425|imex:IM-25995-5	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_021034796.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR001677(Transferrin binding protein)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0009986""(cell surface)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0052562""(symbiont-mediated suppression of host immune response)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR054843"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2A, 2C, 3C and Supp. Figs 1 and 2|comment:Interaction was not disrupted by addition of Factor H|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/02	2025/03/10	rogid:5Q8KhV90bDSBMn6J93XWEagP4LQ727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:42C9B9B66475045D|rigid:aC0Z0buyk6NLBwMBn+nXNRj/5qQ	false	binding-associated region:30-280	necessary binding region:371-381	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:A0A024A2C9	uniprotkb:P04004	intact:EBI-12498321	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:a0a024a2c9_haeif(display_long)|uniprotkb:lph(gene name)|psi-mi:lph(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Al-Jubair et al. (2015)	pubmed:26538390|imex:IM-25995	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12508598|imex:IM-25995-9	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_021034796.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR001677(Transferrin binding protein)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0009986""(cell surface)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0052562""(symbiont-mediated suppression of host immune response)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR054843"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:1A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/02	2025/03/10	rogid:5Q8KhV90bDSBMn6J93XWEagP4LQ727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:D5B7CD07ACAEDABA|rigid:aC0Z0buyk6NLBwMBn+nXNRj/5qQ	false	binding-associated region:30-280|his tag:?-?	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:A0A024A2C9	uniprotkb:P08603	intact:EBI-12498321	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	psi-mi:a0a024a2c9_haeif(display_long)|uniprotkb:lph(gene name)|psi-mi:lph(display_short)	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Al-Jubair et al. (2015)	pubmed:26538390|imex:IM-25995	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12508614|imex:IM-25995-11	intact-miscore:0.71	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_021034796.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR001677(Transferrin binding protein)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0009986""(cell surface)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0052562""(symbiont-mediated suppression of host immune response)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR054843"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	-	-	-	figure legend:2D and S2|comment:Interaction was not disrupted by addition of Vitronectin|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/02	2025/01/22	rogid:5Q8KhV90bDSBMn6J93XWEagP4LQ727	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	intact-crc:B2B5FA1F3D4660D2|rigid:/2t2pVAayAtJNVOwgvWTeCpDddk	false	binding-associated region:30-280	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:A0A024A2C9	uniprotkb:P04004	intact:EBI-12498321	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:a0a024a2c9_haeif(display_long)|uniprotkb:lph(gene name)|psi-mi:lph(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Al-Jubair et al. (2015)	pubmed:26538390|imex:IM-25995	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12513389|imex:IM-25995-17	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_021034796.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR001677(Transferrin binding protein)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0009986""(cell surface)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0052562""(symbiont-mediated suppression of host immune response)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR054843"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:Supp. Figs 1|comment:Interaction was not disrupted by addition of Factor H|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/02	2025/03/31	rogid:5Q8KhV90bDSBMn6J93XWEagP4LQ727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:C6896786A8FB318F|rigid:aC0Z0buyk6NLBwMBn+nXNRj/5qQ	false	binding-associated region:30-280	his tag:?-?	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:A0A024A2C9	uniprotkb:P04004	intact:EBI-12498321	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:a0a024a2c9_haeif(display_long)|uniprotkb:lph(gene name)|psi-mi:lph(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0054""(fluorescence-activated cell sorting)"	Al-Jubair et al. (2015)	pubmed:26538390|imex:IM-25995	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12508622|imex:IM-25995-13	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_021034796.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR001677(Transferrin binding protein)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0009986""(cell surface)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0052562""(symbiont-mediated suppression of host immune response)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR054843"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:1D & 3E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/02	2025/03/10	rogid:5Q8KhV90bDSBMn6J93XWEagP4LQ727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:983B1A9C547D1294|rigid:aC0Z0buyk6NLBwMBn+nXNRj/5qQ	false	-	necessary binding region:371-381	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P04004	uniprotkb:A0A024A2C9	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	intact:EBI-12498321	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:a0a024a2c9_haeif(display_long)|uniprotkb:lph(gene name)|psi-mi:lph(display_short)	"psi-mi:""MI:0054""(fluorescence-activated cell sorting)"	Al-Jubair et al. (2015)	pubmed:26538390|imex:IM-25995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12508628|imex:IM-25995-15	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	"refseq:WP_021034796.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR001677(Transferrin binding protein)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0009986""(cell surface)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0052562""(symbiont-mediated suppression of host immune response)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR054843"	-	-	-	figure legend:1C and 3D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/02	2025/03/10	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:5Q8KhV90bDSBMn6J93XWEagP4LQ727	intact-crc:B763A7B0A65D14BC|rigid:aC0Z0buyk6NLBwMBn+nXNRj/5qQ	false	necessary binding region:371-381	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:A0A024A2C9	uniprotkb:P04004	intact:EBI-12498321	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:a0a024a2c9_haeif(display_long)|uniprotkb:lph(gene name)|psi-mi:lph(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Al-Jubair et al. (2015)	pubmed:26538390|imex:IM-25995	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12499054|imex:IM-25995-7	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_021034796.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR001677(Transferrin binding protein)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0009986""(cell surface)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0052562""(symbiont-mediated suppression of host immune response)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR054843"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.2x10^-6(molar)	2016/08/02	2025/03/10	rogid:5Q8KhV90bDSBMn6J93XWEagP4LQ727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:077E506633B0927E|rigid:aC0Z0buyk6NLBwMBn+nXNRj/5qQ	false	-	sufficient binding region:99-415	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12501510|imex:IM-26237-1	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:74EF84E8DB9966DA|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:429-652|his tag:c-c|binding-associated region:1047-1751|sufficient binding region:1536-2031|sufficient binding region:265-376	sufficient binding region:80-396|his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12501546|imex:IM-26237-3	intact-miscore:0.60	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:BAF9B2D00C8B3F3D|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:80-396|his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12511305|imex:IM-26237-7	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:3F & 4D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:D3A30189ADD9B2DD|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	necessary binding region:352-374|his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12511389|imex:IM-26237-9	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:S3|comment:Multimeric Vn had a  higher Hsf-binding capacity than monomeric  Vn.|comment:Experiment for this interaction it not stated to be an ELISA, but probably is.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:37293B593BB10BA3|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12513499|imex:IM-26237-13	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:6A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:6056E4B14FFABE8E|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	his tag:n-n	his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-16631450|imex:IM-26237-21	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2C and 4|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:E170DC7989745FEB|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:80-396|his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-16631467|imex:IM-26237-22	intact-miscore:0.60	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:D773C91EFD28CB1C	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:80-396|his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-16631480|imex:IM-26237-15	intact-miscore:0.60	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:C1515688F9103DEC|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:80-396|his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-16631495|imex:IM-26237-17	intact-miscore:0.60	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:A5F93C729C6B4E06|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:80-396|his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12501572|imex:IM-26237-19	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.39x10^-8(molar)	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:E44B05A501863C74|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:54-2300|his tag:c-c	sufficient binding region:80-396|his tag:c-c	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12501582|imex:IM-26237-5	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:2D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.58x10^-8(molar)	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:DBD7744775ECEDB1|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	sufficient binding region:429-652|his tag:c-c	sufficient binding region:80-396|his tag:c-c	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q4KTX9	uniprotkb:P04004	intact:EBI-12501515	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q4ktx9_haeif(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0054""(fluorescence-activated cell sorting)"	Singh et al. (2014)	pubmed:24664511|imex:IM-26237	taxid:727(haeif)|taxid:727(Haemophilus influenzae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-12511425|imex:IM-26237-11	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045584|interpro:IPR040482|interpro:IPR024973|interpro:IPR029275|interpro:IPR028230|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR037174|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR054742"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	figure legend:S4|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/09	2025/03/10	rogid:U64TXLciq6IVfCJrDYBjo2JlrUk727	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:1C2FC81D338DEBB4|rigid:jQT1QRLfHtBYouaUi2yJ2wZinsc	false	his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
intact:EBI-4399559	uniprotkb:Q6RCR0	dip:DIP-24261N	intact:EBI-16204127	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:q6rcr0_legpn(display_long)	"psi-mi:""MI:0808""(comigration in sds page)"	Qiu et al. (2016)	doi:10.1038/nature17657|imex:IM-25377|pubmed:27049943	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:446(legpn)|taxid:446(Legionella pneumophila)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16204137|imex:IM-25377-2|dip:DIP-200997E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	"dip:DIP-61977N|go:""GO:0000166""(nucleotide binding)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0106274""(NAD+-protein-arginine ADP-ribosyltransferase activity)|interpro:IPR021014|interpro:IPR043934|interpro:IPR043935|rcsb pdb:5CRA|rcsb pdb:5CRB|rcsb pdb:5CRC|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YIM"	"psi-mi:""MI:0465""(dip)"	no-uniprot-update:	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:KnQeQ2Pr9adRwCP/jU/6+zgpVb4446	intact-crc:A436AB2C8183A323|rigid:Dib5LryEQA6alI8XSqHMFv+PeuY	false	glutathione s tranferase tag:0-0	mutation disrupting interaction strength:867-867,865-865	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-4399559	uniprotkb:Q6RCR0	dip:DIP-24261N	intact:EBI-16204127	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:q6rcr0_legpn(display_long)	"psi-mi:""MI:0808""(comigration in sds page)"	Qiu et al. (2016)	doi:10.1038/nature17657|imex:IM-25377|pubmed:27049943	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:446(legpn)|taxid:446(Legionella pneumophila)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16204179|imex:IM-25377-4|dip:DIP-200997E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	"dip:DIP-61977N|go:""GO:0000166""(nucleotide binding)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0106274""(NAD+-protein-arginine ADP-ribosyltransferase activity)|interpro:IPR021014|interpro:IPR043934|interpro:IPR043935|rcsb pdb:5CRA|rcsb pdb:5CRB|rcsb pdb:5CRC|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YIM"	"psi-mi:""MI:0465""(dip)"	no-uniprot-update:	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2024/11/14	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:KnQeQ2Pr9adRwCP/jU/6+zgpVb4446	intact-crc:B0AF5494AFE0AA89|rigid:Dib5LryEQA6alI8XSqHMFv+PeuY	false	glutathione s tranferase tag:0-0|mutation disrupting interaction strength:42-42	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:H9L447	uniprotkb:P57729	intact:EBI-15950495	intact:EBI-6552718|uniprotkb:Q53XK7|ensembl:ENSP00000243662.5	psi-mi:h9l447_salty(display_long)|uniprotkb:STM1055(locus name)	psi-mi:rab38_human(display_long)|uniprotkb:RAB38(gene name)|psi-mi:RAB38(display_short)|uniprotkb:Melanoma antigen NY-MEL-1(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Spanò et al. (2012)	pubmed:23162001|doi:10.1126/science.1229224|imex:IM-25198	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0570""(protein cleavage)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16023977|imex:IM-25198-2|dip:DIP-200703E	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR047918|rcsb pdb:4MI7|dip:DIP-59798N|refseq:WP_001525490.1	"refseq:NP_071732.1|ensembl:ENSG00000123892.12(gene)|dip:DIP-60520N|ensembl:ENST00000243662.11(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005769""(early endosome)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0012505""(endomembrane system)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0032438""(melanosome organization)|go:""GO:0033162""(melanosome membrane)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0035650""(AP-1 adaptor complex binding)|go:""GO:0035651""(AP-3 adaptor complex binding)|go:""GO:0036461""(BLOC-2 complex binding)|go:""GO:0042470""(melanosome)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0044297""(cell body)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048023""(positive regulation of melanin biosynthetic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0090383""(phagosome acidification)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904377""(positive regulation of protein localization to cell periphery)|go:""GO:2001247""(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030697|rcsb pdb:6HDU|rcsb pdb:6S5H|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2025/02/27	rogid:51UmgykWychSKFZmMRh60XaV6Ws99287	rogid:wE7byI3eUYwjSh5A01J4lL+4dFM9606	intact-crc:7F076001093CB976|rigid:wGEKUVqm9gZCb/lqLu6/fiHtmVE	false	-	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:H9L447	uniprotkb:Q13637	intact:EBI-15950495	intact:EBI-9837586|ensembl:ENSP00000356465.3	psi-mi:h9l447_salty(display_long)|uniprotkb:STM1055(locus name)	psi-mi:rab32_human(display_long)|uniprotkb:RAB32(gene name)|psi-mi:RAB32(display_short)	"psi-mi:""MI:0435""(protease assay)"	Spanò et al. (2012)	pubmed:23162001|doi:10.1126/science.1229224|imex:IM-25198	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0570""(protein cleavage)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16023960|imex:IM-25198-1|dip:DIP-200702E	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR047918|rcsb pdb:4MI7|dip:DIP-59798N|refseq:WP_001525490.1	"ensembl:ENSG00000118508.5(gene)|refseq:NP_006825.1|ensembl:ENST00000367495.4(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0032438""(melanosome organization)|go:""GO:0033162""(melanosome membrane)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0035650""(AP-1 adaptor complex binding)|go:""GO:0035651""(AP-3 adaptor complex binding)|go:""GO:0036461""(BLOC-2 complex binding)|go:""GO:0042470""(melanosome)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0090382""(phagosome maturation)|go:""GO:1903232""(melanosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030697|mint:Q13637|rcsb pdb:4CYM|rcsb pdb:4CZ2|rcsb pdb:5OEC|rcsb pdb:5OED|rcsb pdb:6FF8|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-61889N|panther:PTHR24073(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2025/01/25	rogid:51UmgykWychSKFZmMRh60XaV6Ws99287	rogid:7WV+WUaIbjAZzNi/LqEwmJZ/Y789606	intact-crc:98B0E38234508EED|rigid:qtNwGXDrNyswG05+x0DuswzsoYg	false	-	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:P51151	uniprotkb:Q56061	intact:EBI-4401353|uniprotkb:Q6ICN1|uniprotkb:A8K390|ensembl:ENSP00000420127.1|ensembl:ENSP00000480777.1	intact:EBI-10765408	psi-mi:rab9a_human(display_long)|uniprotkb:RAB9A(gene name)|psi-mi:RAB9A(display_short)|uniprotkb:RAB9(gene name synonym)	psi-mi:sifa_salty(display_long)|uniprotkb:STM1224(locus name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	McGourty et al. (2012)	pubmed:23162002|doi:10.1126/science.1227037|imex:IM-25199	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16024003|imex:IM-25199-1|dip:DIP-200704E	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_016885453.1|refseq:NP_001182257.1|refseq:NP_004242.1|dip:DIP-46409N|ensembl:ENSG00000123595.8(gene)|ensembl:ENST00000464506.2(transcript)|ensembl:ENST00000618931.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|go:""GO:0019003""(GDP binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0032482""(Rab protein signal transduction)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042470""(melanosome)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0052403""(obsolete negative regulation by host of symbiont catalytic activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041824|mint:P51151|rcsb pdb:1WMS|rcsb pdb:7E1T|reactome:R-HSA-6811440|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9706019|panther:PTHR47981(orthology-group)"	"refseq:NP_460194.1|refseq:WP_001520468.1|dip:DIP-46411N|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0044082""(symbiont-mediated perturbation of host small GTPase-mediated signal transduction)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|interpro:IPR010637(Sif)|interpro:IPR044928|rcsb pdb:3CXB|rcsb pdb:3HW2"	"psi-mi:""MI:0465""(dip)"	-	crc64:83C6185148A774B9	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/21	rogid:x0BjgzGEj7mPNlt2CQLkHtqQzDQ9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk99287	intact-crc:0B18F82AB0ADCC7A|rigid:o+kZlYdVjX/yaL2ec+K87tzSZhw	false	green fluorescent protein tag:n-n	mutation disrupting interaction strength:130-130|ha tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q2GJL5	uniprotkb:Q14457	intact:EBI-16025394	intact:EBI-949378|intact:EBI-28978189|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7|ensembl:ENSP00000355231.3|ensembl:ENSP00000465364.1	psi-mi:q2gjl5_anapz(display_long)|uniprotkb:ats-1(gene name)|psi-mi:ats-1(display_short)|uniprotkb:APH_0859(locus name)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Niu et al. (2012)	pubmed:23197835|doi:10.1073/pnas.1218674109|imex:IM-20737	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16025448|imex:IM-20737-3|dip:DIP-190390E	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	dip:DIP-60095N|refseq:WP_020848986.1	"refseq:NP_003757.1|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1|dip:DIP-44611N|ensembl:ENSG00000126581.13(gene)|ensembl:ENST00000361523.8(transcript)|ensembl:ENST00000590099.6(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0000423""(mitophagy)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006914""(autophagy)|go:""GO:0006915""(apoptotic process)|go:""GO:0006968""(cellular defense response)|go:""GO:0006995""(cellular response to nitrogen starvation)|go:""GO:0007040""(lysosome organization)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0007254""(JNK cascade)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010008""(endosome membrane)|go:""GO:0010040""(""response to iron(II) ion"")|go:""GO:0010288""(response to lead ion)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0010613""(positive regulation of cardiac muscle hypertrophy)|go:""GO:0016236""(macroautophagy)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016604""(nuclear body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030425""(dendrite)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032473""(cytoplasmic side of mitochondrial outer membrane)|go:""GO:0032801""(receptor catabolic process)|go:""GO:0033197""(response to vitamin E)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0034271""(phosphatidylinositol 3-kinase complex, class III, type I)|go:""GO:0034272""(phosphatidylinositol 3-kinase complex, class III, type II)|go:""GO:0035032""(phosphatidylinositol 3-kinase complex, class III)|go:""GO:0036092""(phosphatidylinositol-3-phosphate biosynthetic process)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0039521""(obsolete suppression by virus of host autophagy)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0043652""(engulfment of apoptotic cell)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045324""(late endosome to vacuole transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048666""(neuron development)|go:""GO:0050435""(amyloid-beta metabolic process)|go:""GO:0051020""(GTPase binding)|go:""GO:0051301""(cell division)|go:""GO:0051607""(defense response to virus)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071275""(cellular response to aluminum ion)|go:""GO:0071280""(cellular response to copper ion)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0090650""(cellular response to oxygen-glucose deprivation)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098780""(response to mitochondrial depolarisation)|go:""GO:1902425""(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:""GO:1902902""(negative regulation of autophagosome assembly)|go:""GO:1905672""(negative regulation of lysosome organization)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2000786""(positive regulation of autophagosome assembly)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|rcsb pdb:8SOR|rcsb pdb:9C82|reactome:R-HSA-1169408|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|reactome:R-HSA-9705671|reactome:R-HSA-983170|reactome:R-HSA-9833110|panther:PTHR12768(orthology-group)|ensembl:ENSP00000355231.3|ensembl:ENSP00000465364.1"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/02/06	rogid:3q7smL3cJGePKYLFK7Hc0Qpsn1E212042	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	intact-crc:A09D78F118018BD8|rigid:xnxEnMUfNujQIKR96WFEY6lFUFM	false	green fluorescent protein tag:c-c|sufficient binding region:90-250	ha tag:n-n|sufficient binding region:1-272	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q2GJL5	uniprotkb:Q14457	intact:EBI-16025394	intact:EBI-949378|intact:EBI-28978189|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7|ensembl:ENSP00000355231.3|ensembl:ENSP00000465364.1	psi-mi:q2gjl5_anapz(display_long)|uniprotkb:ats-1(gene name)|psi-mi:ats-1(display_short)|uniprotkb:APH_0859(locus name)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Niu et al. (2012)	pubmed:23197835|doi:10.1073/pnas.1218674109|imex:IM-20737	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16025423|imex:IM-20737-2|dip:DIP-190390E	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	dip:DIP-60095N|refseq:WP_020848986.1	"refseq:NP_003757.1|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1|dip:DIP-44611N|ensembl:ENSG00000126581.13(gene)|ensembl:ENST00000361523.8(transcript)|ensembl:ENST00000590099.6(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0000423""(mitophagy)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006914""(autophagy)|go:""GO:0006915""(apoptotic process)|go:""GO:0006968""(cellular defense response)|go:""GO:0006995""(cellular response to nitrogen starvation)|go:""GO:0007040""(lysosome organization)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0007254""(JNK cascade)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010008""(endosome membrane)|go:""GO:0010040""(""response to iron(II) ion"")|go:""GO:0010288""(response to lead ion)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0010613""(positive regulation of cardiac muscle hypertrophy)|go:""GO:0016236""(macroautophagy)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016604""(nuclear body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030425""(dendrite)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032473""(cytoplasmic side of mitochondrial outer membrane)|go:""GO:0032801""(receptor catabolic process)|go:""GO:0033197""(response to vitamin E)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0034271""(phosphatidylinositol 3-kinase complex, class III, type I)|go:""GO:0034272""(phosphatidylinositol 3-kinase complex, class III, type II)|go:""GO:0035032""(phosphatidylinositol 3-kinase complex, class III)|go:""GO:0036092""(phosphatidylinositol-3-phosphate biosynthetic process)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0039521""(obsolete suppression by virus of host autophagy)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0043652""(engulfment of apoptotic cell)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045324""(late endosome to vacuole transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048666""(neuron development)|go:""GO:0050435""(amyloid-beta metabolic process)|go:""GO:0051020""(GTPase binding)|go:""GO:0051301""(cell division)|go:""GO:0051607""(defense response to virus)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071275""(cellular response to aluminum ion)|go:""GO:0071280""(cellular response to copper ion)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0090650""(cellular response to oxygen-glucose deprivation)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098780""(response to mitochondrial depolarisation)|go:""GO:1902425""(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:""GO:1902902""(negative regulation of autophagosome assembly)|go:""GO:1905672""(negative regulation of lysosome organization)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2000786""(positive regulation of autophagosome assembly)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|rcsb pdb:8SOR|rcsb pdb:9C82|reactome:R-HSA-1169408|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|reactome:R-HSA-9705671|reactome:R-HSA-983170|reactome:R-HSA-9833110|panther:PTHR12768(orthology-group)|ensembl:ENSP00000355231.3|ensembl:ENSP00000465364.1"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/02/06	rogid:3q7smL3cJGePKYLFK7Hc0Qpsn1E212042	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	intact-crc:346617772F2CC339|rigid:xnxEnMUfNujQIKR96WFEY6lFUFM	false	sufficient binding region:90-250|green fluorescent protein tag:c-c	ha tag:n-n|sufficient binding region:1-272	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q2GJL5	uniprotkb:Q14457	intact:EBI-16025394	intact:EBI-949378|intact:EBI-28978189|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7|ensembl:ENSP00000355231.3|ensembl:ENSP00000465364.1	psi-mi:q2gjl5_anapz(display_long)|uniprotkb:ats-1(gene name)|psi-mi:ats-1(display_short)|uniprotkb:APH_0859(locus name)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Niu et al. (2012)	pubmed:23197835|doi:10.1073/pnas.1218674109|imex:IM-20737	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16025473|imex:IM-20737-4|dip:DIP-190390E	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	dip:DIP-60095N|refseq:WP_020848986.1	"refseq:NP_003757.1|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1|dip:DIP-44611N|ensembl:ENSG00000126581.13(gene)|ensembl:ENST00000361523.8(transcript)|ensembl:ENST00000590099.6(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0000423""(mitophagy)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006914""(autophagy)|go:""GO:0006915""(apoptotic process)|go:""GO:0006968""(cellular defense response)|go:""GO:0006995""(cellular response to nitrogen starvation)|go:""GO:0007040""(lysosome organization)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0007254""(JNK cascade)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010008""(endosome membrane)|go:""GO:0010040""(""response to iron(II) ion"")|go:""GO:0010288""(response to lead ion)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0010613""(positive regulation of cardiac muscle hypertrophy)|go:""GO:0016236""(macroautophagy)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016604""(nuclear body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030425""(dendrite)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032473""(cytoplasmic side of mitochondrial outer membrane)|go:""GO:0032801""(receptor catabolic process)|go:""GO:0033197""(response to vitamin E)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0034271""(phosphatidylinositol 3-kinase complex, class III, type I)|go:""GO:0034272""(phosphatidylinositol 3-kinase complex, class III, type II)|go:""GO:0035032""(phosphatidylinositol 3-kinase complex, class III)|go:""GO:0036092""(phosphatidylinositol-3-phosphate biosynthetic process)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0039521""(obsolete suppression by virus of host autophagy)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0043652""(engulfment of apoptotic cell)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045324""(late endosome to vacuole transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048666""(neuron development)|go:""GO:0050435""(amyloid-beta metabolic process)|go:""GO:0051020""(GTPase binding)|go:""GO:0051301""(cell division)|go:""GO:0051607""(defense response to virus)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071275""(cellular response to aluminum ion)|go:""GO:0071280""(cellular response to copper ion)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0090650""(cellular response to oxygen-glucose deprivation)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098780""(response to mitochondrial depolarisation)|go:""GO:1902425""(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:""GO:1902902""(negative regulation of autophagosome assembly)|go:""GO:1905672""(negative regulation of lysosome organization)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2000786""(positive regulation of autophagosome assembly)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|rcsb pdb:8SOR|rcsb pdb:9C82|reactome:R-HSA-1169408|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|reactome:R-HSA-9705671|reactome:R-HSA-983170|reactome:R-HSA-9833110|panther:PTHR12768(orthology-group)|ensembl:ENSP00000355231.3|ensembl:ENSP00000465364.1"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/02/06	rogid:3q7smL3cJGePKYLFK7Hc0Qpsn1E212042	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	intact-crc:7CDDEEC7EE4A7D04|rigid:xnxEnMUfNujQIKR96WFEY6lFUFM	false	-	ha tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q2GJL5	uniprotkb:Q14457	intact:EBI-16025394	intact:EBI-949378|intact:EBI-28978189|uniprotkb:O75595|uniprotkb:Q9UNA8|uniprotkb:B2R6N7|ensembl:ENSP00000355231.3|ensembl:ENSP00000465364.1	psi-mi:q2gjl5_anapz(display_long)|uniprotkb:ats-1(gene name)|psi-mi:ats-1(display_short)|uniprotkb:APH_0859(locus name)	psi-mi:becn1_human(display_long)|uniprotkb:Coiled-coil myosin-like BCL2-interacting protein(gene name synonym)|uniprotkb:Protein GT197(gene name synonym)|uniprotkb:BECN1(gene name)|psi-mi:BECN1(display_short)|uniprotkb:GT197(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Niu et al. (2012)	pubmed:23197835|doi:10.1073/pnas.1218674109|imex:IM-20737	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16025402|imex:IM-20737-1|dip:DIP-190390E	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	dip:DIP-60095N|refseq:WP_020848986.1	"refseq:NP_003757.1|refseq:NP_001300927.1|refseq:NP_001300928.1|refseq:NP_001300929.1|dip:DIP-44611N|ensembl:ENSG00000126581.13(gene)|ensembl:ENST00000361523.8(transcript)|ensembl:ENST00000590099.6(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0000423""(mitophagy)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006914""(autophagy)|go:""GO:0006915""(apoptotic process)|go:""GO:0006968""(cellular defense response)|go:""GO:0006995""(cellular response to nitrogen starvation)|go:""GO:0007040""(lysosome organization)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0007254""(JNK cascade)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010008""(endosome membrane)|go:""GO:0010040""(""response to iron(II) ion"")|go:""GO:0010288""(response to lead ion)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0010613""(positive regulation of cardiac muscle hypertrophy)|go:""GO:0016236""(macroautophagy)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016604""(nuclear body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030425""(dendrite)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032473""(cytoplasmic side of mitochondrial outer membrane)|go:""GO:0032801""(receptor catabolic process)|go:""GO:0033197""(response to vitamin E)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0034271""(phosphatidylinositol 3-kinase complex, class III, type I)|go:""GO:0034272""(phosphatidylinositol 3-kinase complex, class III, type II)|go:""GO:0035032""(phosphatidylinositol 3-kinase complex, class III)|go:""GO:0036092""(phosphatidylinositol-3-phosphate biosynthetic process)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0039521""(obsolete suppression by virus of host autophagy)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0043652""(engulfment of apoptotic cell)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045324""(late endosome to vacuole transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048666""(neuron development)|go:""GO:0050435""(amyloid-beta metabolic process)|go:""GO:0051020""(GTPase binding)|go:""GO:0051301""(cell division)|go:""GO:0051607""(defense response to virus)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071275""(cellular response to aluminum ion)|go:""GO:0071280""(cellular response to copper ion)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0090650""(cellular response to oxygen-glucose deprivation)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098780""(response to mitochondrial depolarisation)|go:""GO:1902425""(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:""GO:1902902""(negative regulation of autophagosome assembly)|go:""GO:1905672""(negative regulation of lysosome organization)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2000786""(positive regulation of autophagosome assembly)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR007243(Autophagy protein 6)|interpro:IPR029318|interpro:IPR038274|interpro:IPR040455|interpro:IPR041691|mint:Q14457|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:3DVU|rcsb pdb:4DDP|rcsb pdb:4MI8|rcsb pdb:5EFM|rcsb pdb:5HHE|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6HOI|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:7BL1|rcsb pdb:8SOR|rcsb pdb:9C82|reactome:R-HSA-1169408|reactome:R-HSA-1632852|reactome:R-HSA-5689880|reactome:R-HSA-9679504|reactome:R-HSA-9694676|reactome:R-HSA-9705671|reactome:R-HSA-983170|reactome:R-HSA-9833110|panther:PTHR12768(orthology-group)|ensembl:ENSP00000355231.3|ensembl:ENSP00000465364.1"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2017/08/07	2025/02/06	rogid:3q7smL3cJGePKYLFK7Hc0Qpsn1E212042	rogid:4COK3vvpxbVYRibANONKBFVtX+Q9606	intact-crc:3BFB166B684E9DA1|rigid:xnxEnMUfNujQIKR96WFEY6lFUFM	false	-	sufficient binding region:191-327|sufficient binding region:396-450	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q2GJL5	uniprotkb:Q6ZNE5	intact:EBI-16025394	intact:EBI-2690371|uniprotkb:Q32MK7|uniprotkb:A6NJE4|uniprotkb:Q32MK8|uniprotkb:O94920|uniprotkb:A8K9U5|uniprotkb:B7ZWP5|ensembl:ENSP00000247178.5	psi-mi:q2gjl5_anapz(display_long)|uniprotkb:ats-1(gene name)|psi-mi:ats-1(display_short)|uniprotkb:APH_0859(locus name)	psi-mi:bakor_human(display_long)|uniprotkb:KIAA0831(gene name synonym)|uniprotkb:Autophagy-related protein 14-like protein(gene name synonym)|uniprotkb:ATG14(gene name)|psi-mi:ATG14(display_short)|uniprotkb:ATG14L(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Niu et al. (2012)	pubmed:23197835|doi:10.1073/pnas.1218674109|imex:IM-20737	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16025492|imex:IM-20737-5|dip:DIP-190391E	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	dip:DIP-60095N|refseq:WP_020848986.1	"refseq:XP_011534865.1|refseq:NP_055739.2|dip:DIP-48651N|ensembl:ENSG00000126775.9(gene)|ensembl:ENST00000247178.6(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0000423""(mitophagy)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0005776""(autophagosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005930""(axoneme)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016236""(macroautophagy)|go:""GO:0016240""(autophagosome membrane docking)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0035014""(phosphatidylinositol 3-kinase regulator activity)|go:""GO:0035032""(phosphatidylinositol 3-kinase complex, class III)|go:""GO:0036092""(phosphatidylinositol-3-phosphate biosynthetic process)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0051020""(GTPase binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0090207""(regulation of triglyceride metabolic process)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0097629""(extrinsic component of omegasome membrane)|go:""GO:0097632""(extrinsic component of phagophore assembly site membrane)|go:""GO:0098780""(response to mitochondrial depolarisation)|go:""GO:0141039""(phosphatidylinositol 3-kinase inhibitor activity)|interpro:IPR018791|mint:Q6ZNE5|rcsb pdb:6HOL|rcsb pdb:8SOR|rcsb pdb:9C82|reactome:R-HSA-1632852|reactome:R-HSA-9705671|reactome:R-HSA-983170|ensembl:ENSP00000247178.5|panther:PTHR13664(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/20	rogid:3q7smL3cJGePKYLFK7Hc0Qpsn1E212042	rogid:hAzH6syRuwo7HuR/MOXekHPrkJc9606	intact-crc:ECE380F666AF6FB2|rigid:XIGmeSAMj/hO6Et2msgNDrptn6E	false	necessary binding region:1-17|green fluorescent protein tag:c-c	ha tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:O54081	uniprotkb:P51681	intact:EBI-16027720	intact:EBI-489374|ensembl:ENSP00000292303.4|ensembl:ENSP00000404881.1|uniprotkb:O14692|uniprotkb:O14693|uniprotkb:O14695|uniprotkb:O14696|uniprotkb:O14697|uniprotkb:O14698|uniprotkb:O14699|uniprotkb:O14700|uniprotkb:O14701|uniprotkb:O14702|uniprotkb:O14703|uniprotkb:O14704|uniprotkb:O14705|uniprotkb:O14706|uniprotkb:O14707|uniprotkb:O14708|uniprotkb:O15538|uniprotkb:Q9UPA4	psi-mi:luke_staau(display_long)|uniprotkb:lukE(gene name)|psi-mi:lukE(display_short)	psi-mi:ccr5_human(display_long)|uniprotkb:HIV-1 fusion coreceptor(gene name synonym)|uniprotkb:CHEMR13(gene name synonym)|uniprotkb:CCR5(gene name)|psi-mi:CCR5(display_short)|uniprotkb:CMKBR5(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Alonzo et al. (2013)	pubmed:23235831|doi:10.1038/nature11724|imex:IM-20767	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16027731|imex:IM-20767-1|dip:DIP-190468E	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-60119N|go:""GO:0005576""(extracellular region)|go:""GO:0051715""(cytolysis in another organism)|go:""GO:0090729""(toxin activity)|interpro:IPR003963(Bi-component toxin, staphylococci)|interpro:IPR016183(Leukocidin/porin)|interpro:IPR036435"	"ensembl:ENSG00000160791.14(gene)|ensembl:ENST00000292303.5(transcript)|ensembl:ENST00000445772.1(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001618""(virus receptor activity)|go:""GO:0002407""(dendritic cell chemotaxis)|go:""GO:0003779""(actin binding)|go:""GO:0004435""(phosphatidylinositol-4,5-bisphosphate phospholipase C activity)|go:""GO:0004950""(chemokine receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0014808""(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016493""(C-C chemokine receptor activity)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019957""(C-C chemokine binding)|go:""GO:0023052""(signaling)|go:""GO:0042802""(identical protein binding)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070723""(response to cholesterol)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071791""(""chemokine (C-C motif) ligand 5 binding"")|go:""GO:2000110""(negative regulation of macrophage apoptotic process)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002240(C-C chemokine receptor, type 5)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR050119|mint:P51681|rcsb pdb:2L87|rcsb pdb:2MZX|rcsb pdb:2RLL|rcsb pdb:2RRS|rcsb pdb:4MBS|rcsb pdb:5UIW|rcsb pdb:5YD3|rcsb pdb:5YD4|rcsb pdb:5YD5|rcsb pdb:5YY4|rcsb pdb:6FGP|rcsb pdb:6MEO|rcsb pdb:6MET|rcsb pdb:7F1Q|rcsb pdb:7F1R|rcsb pdb:7F1S|rcsb pdb:7NJZ|rcsb pdb:7NW3|rcsb pdb:7O7F|rcsb pdb:8AS2|rcsb pdb:8AS3|reactome:R-HSA-173107|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|refseq:NP_000570.1|refseq:NP_001093638.1|panther:PTHR10489(orthology-group)|dip:DIP-5866N"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2024/11/14	rogid:l/pPEQlJX0UlqHcBoCfzpDXj5kU1280	rogid:qpXGapPDi9co6c1kf2NgfM1qkA89606	intact-crc:2B1BD3131848E712|rigid:BJ8o4z38nkgUnlaTvXpo5m+5i4s	false	his tag:n-n|sufficient binding region:29-314	ha tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:O54081	uniprotkb:P51681	intact:EBI-16027720	intact:EBI-489374|ensembl:ENSP00000292303.4|ensembl:ENSP00000404881.1|uniprotkb:O14692|uniprotkb:O14693|uniprotkb:O14695|uniprotkb:O14696|uniprotkb:O14697|uniprotkb:O14698|uniprotkb:O14699|uniprotkb:O14700|uniprotkb:O14701|uniprotkb:O14702|uniprotkb:O14703|uniprotkb:O14704|uniprotkb:O14705|uniprotkb:O14706|uniprotkb:O14707|uniprotkb:O14708|uniprotkb:O15538|uniprotkb:Q9UPA4	psi-mi:luke_staau(display_long)|uniprotkb:lukE(gene name)|psi-mi:lukE(display_short)	psi-mi:ccr5_human(display_long)|uniprotkb:HIV-1 fusion coreceptor(gene name synonym)|uniprotkb:CHEMR13(gene name synonym)|uniprotkb:CCR5(gene name)|psi-mi:CCR5(display_short)|uniprotkb:CMKBR5(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Alonzo et al. (2013)	pubmed:23235831|doi:10.1038/nature11724|imex:IM-20767	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16027754|imex:IM-20767-2|dip:DIP-190468E	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-60119N|go:""GO:0005576""(extracellular region)|go:""GO:0051715""(cytolysis in another organism)|go:""GO:0090729""(toxin activity)|interpro:IPR003963(Bi-component toxin, staphylococci)|interpro:IPR016183(Leukocidin/porin)|interpro:IPR036435"	"ensembl:ENSG00000160791.14(gene)|ensembl:ENST00000292303.5(transcript)|ensembl:ENST00000445772.1(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001618""(virus receptor activity)|go:""GO:0002407""(dendritic cell chemotaxis)|go:""GO:0003779""(actin binding)|go:""GO:0004435""(phosphatidylinositol-4,5-bisphosphate phospholipase C activity)|go:""GO:0004950""(chemokine receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0014808""(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016493""(C-C chemokine receptor activity)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019957""(C-C chemokine binding)|go:""GO:0023052""(signaling)|go:""GO:0042802""(identical protein binding)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070723""(response to cholesterol)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071791""(""chemokine (C-C motif) ligand 5 binding"")|go:""GO:2000110""(negative regulation of macrophage apoptotic process)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002240(C-C chemokine receptor, type 5)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR050119|mint:P51681|rcsb pdb:2L87|rcsb pdb:2MZX|rcsb pdb:2RLL|rcsb pdb:2RRS|rcsb pdb:4MBS|rcsb pdb:5UIW|rcsb pdb:5YD3|rcsb pdb:5YD4|rcsb pdb:5YD5|rcsb pdb:5YY4|rcsb pdb:6FGP|rcsb pdb:6MEO|rcsb pdb:6MET|rcsb pdb:7F1Q|rcsb pdb:7F1R|rcsb pdb:7F1S|rcsb pdb:7NJZ|rcsb pdb:7NW3|rcsb pdb:7O7F|rcsb pdb:8AS2|rcsb pdb:8AS3|reactome:R-HSA-173107|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|refseq:NP_000570.1|refseq:NP_001093638.1|panther:PTHR10489(orthology-group)|dip:DIP-5866N"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2024/11/14	rogid:l/pPEQlJX0UlqHcBoCfzpDXj5kU1280	rogid:qpXGapPDi9co6c1kf2NgfM1qkA89606	intact-crc:F73DADCAB91EEA0F|rigid:BJ8o4z38nkgUnlaTvXpo5m+5i4s	false	sufficient binding region:29-314	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P23528	uniprotkb:Q93KQ6	intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629.5|ensembl:ENSP00000432660.1	intact:EBI-16142618	psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym)	psi-mi:q93kq6_yeren(display_long)|uniprotkb:yopO(gene name)|psi-mi:yopO(display_short)	"psi-mi:""MI:0071""(molecular sieving)"	Lee et al. (2015)	pubmed:25664724|doi:10.1038/nsmb.2964|imex:IM-24436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16142741|imex:IM-24436-5|dip:DIP-199133E	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005498.1|ensembl:ENSG00000172757.13(gene)|ensembl:ENST00000308162.10(transcript)|ensembl:ENST00000525451.6(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0009615""(response to virus)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030043""(actin filament fragmentation)|go:""GO:0030426""(growth cone)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032587""(ruffle membrane)|go:""GO:0040019""(positive regulation of embryonic development)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0051293""(establishment of spindle localization)|go:""GO:0061001""(regulation of dendritic spine morphogenesis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|dip:DIP-33000N|panther:PTHR11913(orthology-group)"	"refseq:NP_783721.1|refseq:NP_863565.1|refseq:WP_011100759.1|dip:DIP-61545N|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR019093|interpro:IPR043119|interpro:IPR043120|rcsb pdb:4CI6|rcsb pdb:5CE3"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2025/03/25	rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606	rogid:FqNA7kyspbucA76A65b/VQNfVME630	intact-crc:957C494A2948C973|rigid:+ws5NUOWHzQ01mhBsg3PO3oNLnY	false	-	sufficient binding region:89-729	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q93KQ6	uniprotkb:P60709	intact:EBI-16142618	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|ensembl:ENSP00000494269.1|ensembl:ENSP00000494750.1|ensembl:ENSP00000495995.2|ensembl:ENSP00000501862.1|ensembl:ENSP00000502821.1|uniprotkb:Q96HG5	psi-mi:q93kq6_yeren(display_long)|uniprotkb:yopO(gene name)|psi-mi:yopO(display_short)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	"psi-mi:""MI:0017""(classical fluorescence spectroscopy)"	Lee et al. (2015)	pubmed:25664724|doi:10.1038/nsmb.2964|imex:IM-24436	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16142894|imex:IM-24436-11|dip:DIP-199129E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_783721.1|refseq:NP_863565.1|refseq:WP_011100759.1|dip:DIP-61545N|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR019093|interpro:IPR043119|interpro:IPR043120|rcsb pdb:4CI6|rcsb pdb:5CE3"	"efo:""Orphanet:673556""|efo:""Orphanet:674653""|ensembl:ENSG00000075624.17(gene)|ensembl:ENST00000493945.6(transcript)|ensembl:ENST00000642480.2(transcript)|ensembl:ENST00000646664.1(transcript)|ensembl:ENST00000674681.1(transcript)|ensembl:ENST00000675515.1(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0000786""(nucleosome)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007409""(axonogenesis)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019894""(kinesin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0022898""(regulation of transmembrane transporter activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030424""(axon)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0035060""(brahma complex)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045176""(apical protein localization)|go:""GO:0045202""(synapse)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048156""(tau protein binding)|go:""GO:0048870""(cell motility)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051621""(regulation of norepinephrine uptake)|go:""GO:0051623""(positive regulation of norepinephrine uptake)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070160""(tight junction)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071564""(npBAF complex)|go:""GO:0071565""(nBAF complex)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0072562""(blood microparticle)|go:""GO:0072749""(cellular response to cytochalasin B)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140092""(bBAF complex)|go:""GO:0140288""(GBAF complex)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000779""(regulation of double-strand break repair)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|rcsb pdb:7P1H|rcsb pdb:7QJ6|rcsb pdb:7QJ9|rcsb pdb:7VDV|rcsb pdb:7W28|rcsb pdb:7W29|rcsb pdb:7Y8R|rcsb pdb:7ZTC|rcsb pdb:7ZTD|rcsb pdb:8COG|rcsb pdb:8DNH|rcsb pdb:8IB8|rcsb pdb:8OI8|rcsb pdb:8OID|rcsb pdb:8QR1|rcsb pdb:8RTT|rcsb pdb:8RTY|rcsb pdb:8RU2|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|rcsb pdb:8XVT|rcsb pdb:9C57|rcsb pdb:9C62|rcsb pdb:9C6N|rcsb pdb:9FJM|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-9824585|reactome:R-HSA-983231|reactome:R-HSA-9845323|refseq:NP_001092.1|efo:""Orphanet:2995""|efo:""Orphanet:64755""|efo:""Orphanet:79107""|dip:DIP-29686N|panther:PTHR11937(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2025/02/27	rogid:FqNA7kyspbucA76A65b/VQNfVME630	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	intact-crc:2F5F2CBAE4866C52|rigid:JnZFNCRgNWw3rx5h2i3hadBfNdY	false	sufficient binding region:89-729|mutation decreasing interaction strength:245-245	pyrene label:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P40121	uniprotkb:Q93KQ6	intact:EBI-4291044|uniprotkb:D6W5K8|uniprotkb:Q53SA7|uniprotkb:B8ZZS7|ensembl:ENSP00000263867.4|ensembl:ENSP00000386315.1|ensembl:ENSP00000386965.1	intact:EBI-16142618	psi-mi:capg_human(display_long)|uniprotkb:CAPG(gene name)|psi-mi:CAPG(display_short)|uniprotkb:AFCP(gene name synonym)|uniprotkb:MCP(gene name synonym)|uniprotkb:Actin regulatory protein CAP-G(gene name synonym)	psi-mi:q93kq6_yeren(display_long)|uniprotkb:yopO(gene name)|psi-mi:yopO(display_short)	"psi-mi:""MI:0071""(molecular sieving)"	Lee et al. (2015)	pubmed:25664724|doi:10.1038/nsmb.2964|imex:IM-24436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16142874|imex:IM-24436-10|dip:DIP-199134E	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001738.2|refseq:XP_011531424.1|refseq:XP_011531425.1|refseq:NP_001243068.1|refseq:NP_001307661.1|refseq:NP_001307662.1|refseq:NP_001243069.1|dip:DIP-61547N|ensembl:ENSG00000042493.16(gene)|ensembl:ENST00000263867.9(transcript)|ensembl:ENST00000409670.5(transcript)|ensembl:ENST00000409724.5(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005814""(centriole)|go:""GO:0007417""(central nervous system development)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0042470""(melanosome)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090543""(Flemming body)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|mint:P40121|rcsb pdb:1J72|rcsb pdb:1JHW|panther:PTHR11977(orthology-group)"	"refseq:NP_783721.1|refseq:NP_863565.1|refseq:WP_011100759.1|dip:DIP-61545N|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR019093|interpro:IPR043119|interpro:IPR043120|rcsb pdb:4CI6|rcsb pdb:5CE3"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2025/01/27	rogid:QgyN9LayNHJZaKZygTug8GAs6QE9606	rogid:FqNA7kyspbucA76A65b/VQNfVME630	intact-crc:C976DC6029258662|rigid:TC5sCx86uJfvfTJ6Ij+h6UHJjeA	false	-	sufficient binding region:89-729	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UI21	uniprotkb:Q13158	intact:EBI-16070376	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074301|imex:IM-21937-5|dip:DIP-192555E	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/02/06	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	intact-crc:08C090E430815044|rigid:X+0aOvHG2QhQLBsQjsB9YlxXfpA	false	enhanced green fluorescent protein tag:n-n	necessary binding region:97-208|flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:B7UI21	uniprotkb:Q13158	intact:EBI-16070376	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074243|imex:IM-21937-2|dip:DIP-192555E	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2017/08/07	2025/02/06	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	intact-crc:F84A5B6DE0F4E50E|rigid:X+0aOvHG2QhQLBsQjsB9YlxXfpA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B7UI21	uniprotkb:Q13158	intact:EBI-16070376	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074345|imex:IM-21937-7|dip:DIP-192555E	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2017/08/07	2025/02/06	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	intact-crc:1303534DD9659D31|rigid:X+0aOvHG2QhQLBsQjsB9YlxXfpA	false	-	sufficient binding region:97-208	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UI21	uniprotkb:Q13158	intact:EBI-16070376	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074324|imex:IM-21937-6|dip:DIP-192555E	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/02/06	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	intact-crc:63FE7B09EEF9A5F6|rigid:X+0aOvHG2QhQLBsQjsB9YlxXfpA	false	enhanced green fluorescent protein tag:n-n	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q13546	refseq:NP_289553	intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808.3	intact:EBI-16074260|dip:DIP-60594N	psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)	psi-mi:ehecnleb1(display_long)	"psi-mi:""MI:0018""(two hybrid)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:155864(""escherichia coli o157:h7 str. edl933"")|taxid:155864(""Escherichia coli O157:H7 str. EDL933"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074263|imex:IM-21937-3|dip:DIP-192558E	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137275.16(gene)|ensembl:ENST00000259808.9(transcript)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005123""(death receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043068""(positive regulation of programmed cell death)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060545""(positive regulation of necroptotic process)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0070105""(positive regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070231""(T cell apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070513""(death domain binding)|go:""GO:0070926""(""regulation of ATP:ADP antiporter activity"")|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097342""(ripoptosome)|go:""GO:0097343""(ripoptosome assembly)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901026""(ripoptosome assembly involved in necroptotic process)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1903800""(positive regulation of miRNA processing)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR037934|interpro:IPR051681|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|rcsb pdb:7CJB|rcsb pdb:7FCZ|rcsb pdb:7FD0|rcsb pdb:7XMK|rcsb pdb:7YDX|rcsb pdb:8I2N|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9692913|reactome:R-HSA-9693928|refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|efo:""Orphanet:529977""|panther:PTHR44329(orthology-group)"	-	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2017/08/07	2025/03/26	rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606	-	intact-crc:5C2B76E1605F220A	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UI21	uniprotkb:Q15628	intact:EBI-16070376	intact:EBI-359215|uniprotkb:Q52NZ1|uniprotkb:B2RDS3|uniprotkb:B3KQZ9|ensembl:ENSP00000341268.4	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:tradd_human(display_long)|uniprotkb:TRADD(gene name)|psi-mi:TRADD(display_short)|uniprotkb:TNFRSF1A-associated via death domain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074280|imex:IM-21937-4|dip:DIP-192228E	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"panther:PTHR14913(orthology-group)|refseq:NP_003780.1|refseq:NP_001310481.1|refseq:XP_005256270.1|refseq:XP_016879304.1|dip:DIP-285N|ensembl:ENSG00000102871.16(gene)|ensembl:ENST00000345057.9(transcript)|go:""GO:0002947""(tumor necrosis factor receptor superfamily complex)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051798""(positive regulation of hair follicle development)|go:""GO:0070513""(death domain binding)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR009095(TRADD, N-terminal)|interpro:IPR011029(DEATH-like)|interpro:IPR035712|interpro:IPR036729|mint:Q15628|rcsb pdb:1F2H|rcsb pdb:1F3V|rcsb pdb:5XME|rcsb pdb:6AC0|rcsb pdb:7CSQ|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9693928"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/26	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:waTMnn0uXSbf7bracJUScX9ckEc9606	intact-crc:5326CBBDB909CD6E|rigid:h8gI1MgXbpl6MJuwFXU28N1njI4	false	ha tag:c-c	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q13546	uniprotkb:B7UNX3	intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808.3	intact:EBI-16074364	psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)	psi-mi:nleb2_eco27(display_long)|uniprotkb:nleB2(gene name)|psi-mi:nleB2(display_short)|uniprotkb:Non-LEE-encoded type III effector B2(gene name synonym)|uniprotkb:E2348C_1041(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074371|imex:IM-21937-8|dip:DIP-192560E	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137275.16(gene)|ensembl:ENST00000259808.9(transcript)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005123""(death receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043068""(positive regulation of programmed cell death)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060545""(positive regulation of necroptotic process)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0070105""(positive regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070231""(T cell apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070513""(death domain binding)|go:""GO:0070926""(""regulation of ATP:ADP antiporter activity"")|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097342""(ripoptosome)|go:""GO:0097343""(ripoptosome assembly)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901026""(ripoptosome assembly involved in necroptotic process)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1903800""(positive regulation of miRNA processing)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR037934|interpro:IPR051681|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|rcsb pdb:7CJB|rcsb pdb:7FCZ|rcsb pdb:7FD0|rcsb pdb:7XMK|rcsb pdb:7YDX|rcsb pdb:8I2N|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9692913|reactome:R-HSA-9693928|refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|efo:""Orphanet:529977""|panther:PTHR44329(orthology-group)"	"refseq:WP_000950813.1|dip:DIP-60596N|go:""GO:0005576""(extracellular region)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0043657""(host cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/26	rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606	rogid:POe2WvdSIzIj55mcyAqXFwvUyqY574521	intact-crc:5569245B9056A842|rigid:eldF4/N8tFL9+Kyri8LHNH41Y6k	false	flag tag:c-c	enhanced green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:B7UI21	uniprotkb:Q13546	intact:EBI-16070376	intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808.3	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074434|imex:IM-21937-11|dip:DIP-192556E	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"ensembl:ENSG00000137275.16(gene)|ensembl:ENST00000259808.9(transcript)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005123""(death receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043068""(positive regulation of programmed cell death)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060545""(positive regulation of necroptotic process)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0070105""(positive regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070231""(T cell apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070513""(death domain binding)|go:""GO:0070926""(""regulation of ATP:ADP antiporter activity"")|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097342""(ripoptosome)|go:""GO:0097343""(ripoptosome assembly)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901026""(ripoptosome assembly involved in necroptotic process)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1903800""(positive regulation of miRNA processing)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR037934|interpro:IPR051681|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|rcsb pdb:7CJB|rcsb pdb:7FCZ|rcsb pdb:7FD0|rcsb pdb:7XMK|rcsb pdb:7YDX|rcsb pdb:8I2N|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9692913|reactome:R-HSA-9693928|refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|efo:""Orphanet:529977""|panther:PTHR44329(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2017/08/07	2025/03/26	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606	intact-crc:0407ACFD4FEAAEF2|rigid:TXZRWl5TpechDT6fq0enFd/Iu1E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13158	refseq:NP_289553	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	intact:EBI-16074260|dip:DIP-60594N	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	psi-mi:ehecnleb1(display_long)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:155864(""escherichia coli o157:h7 str. edl933"")|taxid:155864(""Escherichia coli O157:H7 str. EDL933"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074451|imex:IM-21937-12|dip:DIP-192557E	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	-	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/02/06	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	-	intact-crc:9A8BB38BCDCEADF2	false	necessary binding region:97-208|flag tag:c-c	enhanced green fluorescent protein tag:0-0	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:B7UI21	uniprotkb:Q15628	intact:EBI-16070376	intact:EBI-359215|uniprotkb:Q52NZ1|uniprotkb:B2RDS3|uniprotkb:B3KQZ9|ensembl:ENSP00000341268.4	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:tradd_human(display_long)|uniprotkb:TRADD(gene name)|psi-mi:TRADD(display_short)|uniprotkb:TNFRSF1A-associated via death domain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074413|imex:IM-21937-10|dip:DIP-192228E	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"panther:PTHR14913(orthology-group)|refseq:NP_003780.1|refseq:NP_001310481.1|refseq:XP_005256270.1|refseq:XP_016879304.1|dip:DIP-285N|ensembl:ENSG00000102871.16(gene)|ensembl:ENST00000345057.9(transcript)|go:""GO:0002947""(tumor necrosis factor receptor superfamily complex)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051798""(positive regulation of hair follicle development)|go:""GO:0070513""(death domain binding)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR009095(TRADD, N-terminal)|interpro:IPR011029(DEATH-like)|interpro:IPR035712|interpro:IPR036729|mint:Q15628|rcsb pdb:1F2H|rcsb pdb:1F3V|rcsb pdb:5XME|rcsb pdb:6AC0|rcsb pdb:7CSQ|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9693928"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/26	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:waTMnn0uXSbf7bracJUScX9ckEc9606	intact-crc:FFEFC918F0345059|rigid:h8gI1MgXbpl6MJuwFXU28N1njI4	false	enhanced green fluorescent protein tag:n-n	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:B7UI21	uniprotkb:Q13546	intact:EBI-16070376	intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808.3	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074392|imex:IM-21937-9|dip:DIP-192556E	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"ensembl:ENSG00000137275.16(gene)|ensembl:ENST00000259808.9(transcript)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005123""(death receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043068""(positive regulation of programmed cell death)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060545""(positive regulation of necroptotic process)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0070105""(positive regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070231""(T cell apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070513""(death domain binding)|go:""GO:0070926""(""regulation of ATP:ADP antiporter activity"")|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097342""(ripoptosome)|go:""GO:0097343""(ripoptosome assembly)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901026""(ripoptosome assembly involved in necroptotic process)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1903800""(positive regulation of miRNA processing)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR037934|interpro:IPR051681|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|rcsb pdb:7CJB|rcsb pdb:7FCZ|rcsb pdb:7FD0|rcsb pdb:7XMK|rcsb pdb:7YDX|rcsb pdb:8I2N|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9692913|reactome:R-HSA-9693928|refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|efo:""Orphanet:529977""|panther:PTHR44329(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/26	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606	intact-crc:8753399FDF681317|rigid:TXZRWl5TpechDT6fq0enFd/Iu1E	false	ha tag:c-c	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:B7UI21	uniprotkb:Q13158	intact:EBI-16070376	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	"psi-mi:""MI:1007""(glycosylase assay)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0559""(glycosylation reaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074494|imex:IM-21937-14|dip:DIP-192555E	intact-miscore:0.59	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2025/02/06	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	intact-crc:0F6063E476900DFC|rigid:X+0aOvHG2QhQLBsQjsB9YlxXfpA	false	-	omega-N-glucosyl-L-arginine:117-117|mutation disrupting interaction rate:117-117	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UI21	uniprotkb:Q13546	intact:EBI-16070376	intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808.3	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074474|imex:IM-21937-13|dip:DIP-192556E	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"ensembl:ENSG00000137275.16(gene)|ensembl:ENST00000259808.9(transcript)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005123""(death receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043068""(positive regulation of programmed cell death)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060545""(positive regulation of necroptotic process)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0070105""(positive regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070231""(T cell apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070513""(death domain binding)|go:""GO:0070926""(""regulation of ATP:ADP antiporter activity"")|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097342""(ripoptosome)|go:""GO:0097343""(ripoptosome assembly)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901026""(ripoptosome assembly involved in necroptotic process)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1903800""(positive regulation of miRNA processing)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR037934|interpro:IPR051681|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|rcsb pdb:7CJB|rcsb pdb:7FCZ|rcsb pdb:7FD0|rcsb pdb:7XMK|rcsb pdb:7YDX|rcsb pdb:8I2N|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9692913|reactome:R-HSA-9693928|refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|efo:""Orphanet:529977""|panther:PTHR44329(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2017/08/07	2025/03/26	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606	intact-crc:86B970FB9A032519|rigid:TXZRWl5TpechDT6fq0enFd/Iu1E	false	-	sufficient binding region:583-671	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UI21	uniprotkb:Q13546	intact:EBI-16070376	intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808.3	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074516|imex:IM-21937-15|dip:DIP-192556E	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"ensembl:ENSG00000137275.16(gene)|ensembl:ENST00000259808.9(transcript)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005123""(death receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043068""(positive regulation of programmed cell death)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060545""(positive regulation of necroptotic process)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0070105""(positive regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070231""(T cell apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070513""(death domain binding)|go:""GO:0070926""(""regulation of ATP:ADP antiporter activity"")|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097342""(ripoptosome)|go:""GO:0097343""(ripoptosome assembly)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901026""(ripoptosome assembly involved in necroptotic process)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1903800""(positive regulation of miRNA processing)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR037934|interpro:IPR051681|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|rcsb pdb:7CJB|rcsb pdb:7FCZ|rcsb pdb:7FD0|rcsb pdb:7XMK|rcsb pdb:7YDX|rcsb pdb:8I2N|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9692913|reactome:R-HSA-9693928|refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|efo:""Orphanet:529977""|panther:PTHR44329(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/26	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606	intact-crc:5FE8892356ABAD92|rigid:TXZRWl5TpechDT6fq0enFd/Iu1E	false	enhanced green fluorescent protein tag:n-n	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q13158	refseq:NP_289553	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	intact:EBI-16074260|dip:DIP-60594N	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	psi-mi:ehecnleb1(display_long)	"psi-mi:""MI:0018""(two hybrid)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:155864(""escherichia coli o157:h7 str. edl933"")|taxid:155864(""Escherichia coli O157:H7 str. EDL933"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074537|imex:IM-21937-16|dip:DIP-192557E	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	-	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2017/08/07	2025/02/06	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	-	intact-crc:FA766DB513C9E0CB	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13158	uniprotkb:D2TT37	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	intact:EBI-16074554	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	psi-mi:d2tt37_citri(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:ROD_10831(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074563|imex:IM-21937-17|dip:DIP-192559E	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	refseq:WP_012905389.1|dip:DIP-60595N	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/02/06	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	rogid:KLWGZ0Fi/p4BqlXH8lxeO8l+IU8637910	intact-crc:E604E439F4AEECB5|rigid:pWW9GKnqzO1jjaoR/ornmMycMOg	false	necessary binding region:97-208|flag tag:c-c	enhanced green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:B7UI21	uniprotkb:Q13158	intact:EBI-16070376	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	"psi-mi:""MI:1007""(glycosylase assay)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0559""(glycosylation reaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074586|imex:IM-21937-18|dip:DIP-192555E	intact-miscore:0.59	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2025/02/06	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	intact-crc:03552C5257833368|rigid:X+0aOvHG2QhQLBsQjsB9YlxXfpA	false	mutation disrupting interaction rate:223-223,221-221	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UI21	uniprotkb:Q13158	intact:EBI-16070376	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pearson et al. (2013)	pubmed:24025841|doi:10.1038/nature12524|imex:IM-21937	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16074607|imex:IM-21937-19|dip:DIP-192555E	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/02/06	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	intact-crc:713267029D346319|rigid:X+0aOvHG2QhQLBsQjsB9YlxXfpA	false	ha tag:c-c	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P0DPI0	uniprotkb:Q496J9	intact:EBI-8178893|uniprotkb:P18639|intact:MINT-1795451|uniprotkb:P01561|uniprotkb:A5HZZ9|uniprotkb:A7G1U9|uniprotkb:P10845	intact:EBI-16081469|intact:EBI-28984041|uniprotkb:Q496K1|uniprotkb:Q9UPU8|ensembl:ENSP00000423541.2	psi-mi:bxa1_clobo(display_long)|uniprotkb:botA(gene name)|psi-mi:botA(display_short)|uniprotkb:atx(gene name synonym)|uniprotkb:Bontoxilysin-A(gene name synonym)|uniprotkb:Botulinum neurotoxin type A1(gene name synonym)|uniprotkb:bonT(gene name synonym)	psi-mi:sv2c_human(display_long)|uniprotkb:SV2C(gene name)|psi-mi:SV2C(display_short)|uniprotkb:KIAA1054(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Benoit et al. (2014)	pubmed:24240280|doi:10.1038/nature12732|imex:IM-22354	taxid:1491(clobo)|taxid:1491(Clostridium botulinum)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16081503|imex:IM-22354-1|dip:DIP-195895E	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR012500(Clostridium neurotoxin, translocation)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR036248|refseq:WP_003356619.1|refseq:WP_011948511.1|mint:P0DPI0|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044231""(host cell presynaptic membrane)|go:""GO:0090729""(toxin activity)|go:""GO:1905576""(ganglioside GT1b binding)|rcsb pdb:1XTF|rcsb pdb:1XTG|rcsb pdb:2ILP|rcsb pdb:2IMA|rcsb pdb:2IMB|rcsb pdb:2IMC|rcsb pdb:2ISE|rcsb pdb:2ISG|rcsb pdb:2ISH|rcsb pdb:2VU9|rcsb pdb:2VUA|rcsb pdb:2W2D|rcsb pdb:3BOK|rcsb pdb:3BON|rcsb pdb:3BOO|rcsb pdb:3V0A|rcsb pdb:3V0B|rcsb pdb:3V0C|rcsb pdb:3ZUR|rcsb pdb:3ZUS|rcsb pdb:4HEV|rcsb pdb:4IQP|rcsb pdb:4JRA|rcsb pdb:5JLV|rcsb pdb:5JMC|rcsb pdb:5MK6|rcsb pdb:5MK7|rcsb pdb:5TPB|rcsb pdb:5TPC|rcsb pdb:5V8P|rcsb pdb:5V8R|rcsb pdb:5V8U|rcsb pdb:5VGV|rcsb pdb:5VGX|rcsb pdb:6DKK|rcsb pdb:6MHJ|rcsb pdb:6XCB|rcsb pdb:6XCC|rcsb pdb:6XCD|rcsb pdb:6XCE|rcsb pdb:6XCF|rcsb pdb:7KYF|rcsb pdb:7KYH|rcsb pdb:7LZP|rcsb pdb:7M1H|reactome:R-HSA-5250968"	"refseq:NP_055794.3|refseq:XP_011541583.1|refseq:XP_011541584.2|dip:DIP-60687N|ensembl:ENSG00000122012.14(gene)|ensembl:ENST00000502798.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0098691""(dopaminergic synapse)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR001646(Pentapeptide repeat)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR022308|interpro:IPR036259|rcsb pdb:4JRA|rcsb pdb:5JLV|rcsb pdb:5MOY|rcsb pdb:6ES1|rcsb pdb:7UIA|rcsb pdb:7UIB|reactome:R-HSA-5250955|reactome:R-HSA-5250968|reactome:R-HSA-5250981|panther:PTHR23511(orthology-group)"	"psi-mi:""MI:0465""(dip)"	"comment:mint|function:""\""Inhibits acetylcholine release. The botulinum toxin binds with high affinity to peripheral neuronal presynaptic membrane to the secretory vesicle protein SV2. It binds directly to the largest luminal loop of SV2A, SV2B and SV2C. It is then internalized by receptor-mediated endocytosis. The C-terminus of the heavy chain (H) is responsible for the adherence of the toxin to the cell surface while the N-terminus mediates transport of the light chain from the endocytic vesicle to the cytosol. After translocation, the light chain (L) hydrolyzes the 197-Gln-|-Arg-198 bond in SNAP-25, thereby blocking neurotransmitter release. Inhibition of acetylcholine release results in flaccid paralysis, with frequent heart or respiratory failure\"""""	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2025/03/01	rogid:15Vc5B8nPpFHrwDzDcAWGGZaryk1491	rogid:ETD+5WxItqT0sxuqbQJzqhAPtF89606	intact-crc:2B36D086E7F8DF7C|rigid:JeZpKGX5O9xYo16ZmgtYY9nNojU	false	sufficient binding region:871-1296	sufficient binding region:456-574	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P0DPI0	uniprotkb:Q496J9	intact:EBI-8178893|uniprotkb:P18639|intact:MINT-1795451|uniprotkb:P01561|uniprotkb:A5HZZ9|uniprotkb:A7G1U9|uniprotkb:P10845	intact:EBI-16081469|intact:EBI-28984041|uniprotkb:Q496K1|uniprotkb:Q9UPU8|ensembl:ENSP00000423541.2	psi-mi:bxa1_clobo(display_long)|uniprotkb:botA(gene name)|psi-mi:botA(display_short)|uniprotkb:atx(gene name synonym)|uniprotkb:Bontoxilysin-A(gene name synonym)|uniprotkb:Botulinum neurotoxin type A1(gene name synonym)|uniprotkb:bonT(gene name synonym)	psi-mi:sv2c_human(display_long)|uniprotkb:SV2C(gene name)|psi-mi:SV2C(display_short)|uniprotkb:KIAA1054(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Benoit et al. (2014)	pubmed:24240280|doi:10.1038/nature12732|imex:IM-22354	taxid:1491(clobo)|taxid:1491(Clostridium botulinum)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16081524|imex:IM-22354-2|dip:DIP-195895E	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR012500(Clostridium neurotoxin, translocation)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR036248|refseq:WP_003356619.1|refseq:WP_011948511.1|mint:P0DPI0|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044231""(host cell presynaptic membrane)|go:""GO:0090729""(toxin activity)|go:""GO:1905576""(ganglioside GT1b binding)|rcsb pdb:1XTF|rcsb pdb:1XTG|rcsb pdb:2ILP|rcsb pdb:2IMA|rcsb pdb:2IMB|rcsb pdb:2IMC|rcsb pdb:2ISE|rcsb pdb:2ISG|rcsb pdb:2ISH|rcsb pdb:2VU9|rcsb pdb:2VUA|rcsb pdb:2W2D|rcsb pdb:3BOK|rcsb pdb:3BON|rcsb pdb:3BOO|rcsb pdb:3V0A|rcsb pdb:3V0B|rcsb pdb:3V0C|rcsb pdb:3ZUR|rcsb pdb:3ZUS|rcsb pdb:4HEV|rcsb pdb:4IQP|rcsb pdb:4JRA|rcsb pdb:5JLV|rcsb pdb:5JMC|rcsb pdb:5MK6|rcsb pdb:5MK7|rcsb pdb:5TPB|rcsb pdb:5TPC|rcsb pdb:5V8P|rcsb pdb:5V8R|rcsb pdb:5V8U|rcsb pdb:5VGV|rcsb pdb:5VGX|rcsb pdb:6DKK|rcsb pdb:6MHJ|rcsb pdb:6XCB|rcsb pdb:6XCC|rcsb pdb:6XCD|rcsb pdb:6XCE|rcsb pdb:6XCF|rcsb pdb:7KYF|rcsb pdb:7KYH|rcsb pdb:7LZP|rcsb pdb:7M1H|reactome:R-HSA-5250968"	"refseq:NP_055794.3|refseq:XP_011541583.1|refseq:XP_011541584.2|dip:DIP-60687N|ensembl:ENSG00000122012.14(gene)|ensembl:ENST00000502798.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0098691""(dopaminergic synapse)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR001646(Pentapeptide repeat)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR022308|interpro:IPR036259|rcsb pdb:4JRA|rcsb pdb:5JLV|rcsb pdb:5MOY|rcsb pdb:6ES1|rcsb pdb:7UIA|rcsb pdb:7UIB|reactome:R-HSA-5250955|reactome:R-HSA-5250968|reactome:R-HSA-5250981|panther:PTHR23511(orthology-group)"	"psi-mi:""MI:0465""(dip)"	"comment:mint|function:""\""Inhibits acetylcholine release. The botulinum toxin binds with high affinity to peripheral neuronal presynaptic membrane to the secretory vesicle protein SV2. It binds directly to the largest luminal loop of SV2A, SV2B and SV2C. It is then internalized by receptor-mediated endocytosis. The C-terminus of the heavy chain (H) is responsible for the adherence of the toxin to the cell surface while the N-terminus mediates transport of the light chain from the endocytic vesicle to the cytosol. After translocation, the light chain (L) hydrolyzes the 197-Gln-|-Arg-198 bond in SNAP-25, thereby blocking neurotransmitter release. Inhibition of acetylcholine release results in flaccid paralysis, with frequent heart or respiratory failure\"""""	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2025/03/01	rogid:15Vc5B8nPpFHrwDzDcAWGGZaryk1491	rogid:ETD+5WxItqT0sxuqbQJzqhAPtF89606	intact-crc:45E5F2B4BE4D678B|rigid:JeZpKGX5O9xYo16ZmgtYY9nNojU	false	his tag:n-n|sufficient binding region:871-1296	sufficient binding region:456-574|mutation disrupting interaction strength:563-563	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:P0DPI0	uniprotkb:Q496J9	intact:EBI-8178893|uniprotkb:P18639|intact:MINT-1795451|uniprotkb:P01561|uniprotkb:A5HZZ9|uniprotkb:A7G1U9|uniprotkb:P10845	intact:EBI-16081469|intact:EBI-28984041|uniprotkb:Q496K1|uniprotkb:Q9UPU8|ensembl:ENSP00000423541.2	psi-mi:bxa1_clobo(display_long)|uniprotkb:botA(gene name)|psi-mi:botA(display_short)|uniprotkb:atx(gene name synonym)|uniprotkb:Bontoxilysin-A(gene name synonym)|uniprotkb:Botulinum neurotoxin type A1(gene name synonym)|uniprotkb:bonT(gene name synonym)	psi-mi:sv2c_human(display_long)|uniprotkb:SV2C(gene name)|psi-mi:SV2C(display_short)|uniprotkb:KIAA1054(gene name synonym)	"psi-mi:""MI:0017""(classical fluorescence spectroscopy)"	Benoit et al. (2014)	pubmed:24240280|doi:10.1038/nature12732|imex:IM-22354	taxid:1491(clobo)|taxid:1491(Clostridium botulinum)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16081583|imex:IM-22354-4|dip:DIP-195895E	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR012500(Clostridium neurotoxin, translocation)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR036248|refseq:WP_003356619.1|refseq:WP_011948511.1|mint:P0DPI0|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044231""(host cell presynaptic membrane)|go:""GO:0090729""(toxin activity)|go:""GO:1905576""(ganglioside GT1b binding)|rcsb pdb:1XTF|rcsb pdb:1XTG|rcsb pdb:2ILP|rcsb pdb:2IMA|rcsb pdb:2IMB|rcsb pdb:2IMC|rcsb pdb:2ISE|rcsb pdb:2ISG|rcsb pdb:2ISH|rcsb pdb:2VU9|rcsb pdb:2VUA|rcsb pdb:2W2D|rcsb pdb:3BOK|rcsb pdb:3BON|rcsb pdb:3BOO|rcsb pdb:3V0A|rcsb pdb:3V0B|rcsb pdb:3V0C|rcsb pdb:3ZUR|rcsb pdb:3ZUS|rcsb pdb:4HEV|rcsb pdb:4IQP|rcsb pdb:4JRA|rcsb pdb:5JLV|rcsb pdb:5JMC|rcsb pdb:5MK6|rcsb pdb:5MK7|rcsb pdb:5TPB|rcsb pdb:5TPC|rcsb pdb:5V8P|rcsb pdb:5V8R|rcsb pdb:5V8U|rcsb pdb:5VGV|rcsb pdb:5VGX|rcsb pdb:6DKK|rcsb pdb:6MHJ|rcsb pdb:6XCB|rcsb pdb:6XCC|rcsb pdb:6XCD|rcsb pdb:6XCE|rcsb pdb:6XCF|rcsb pdb:7KYF|rcsb pdb:7KYH|rcsb pdb:7LZP|rcsb pdb:7M1H|reactome:R-HSA-5250968"	"refseq:NP_055794.3|refseq:XP_011541583.1|refseq:XP_011541584.2|dip:DIP-60687N|ensembl:ENSG00000122012.14(gene)|ensembl:ENST00000502798.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0098691""(dopaminergic synapse)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR001646(Pentapeptide repeat)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR022308|interpro:IPR036259|rcsb pdb:4JRA|rcsb pdb:5JLV|rcsb pdb:5MOY|rcsb pdb:6ES1|rcsb pdb:7UIA|rcsb pdb:7UIB|reactome:R-HSA-5250955|reactome:R-HSA-5250968|reactome:R-HSA-5250981|panther:PTHR23511(orthology-group)"	"psi-mi:""MI:0465""(dip)"	"comment:mint|function:""\""Inhibits acetylcholine release. The botulinum toxin binds with high affinity to peripheral neuronal presynaptic membrane to the secretory vesicle protein SV2. It binds directly to the largest luminal loop of SV2A, SV2B and SV2C. It is then internalized by receptor-mediated endocytosis. The C-terminus of the heavy chain (H) is responsible for the adherence of the toxin to the cell surface while the N-terminus mediates transport of the light chain from the endocytic vesicle to the cytosol. After translocation, the light chain (L) hydrolyzes the 197-Gln-|-Arg-198 bond in SNAP-25, thereby blocking neurotransmitter release. Inhibition of acetylcholine release results in flaccid paralysis, with frequent heart or respiratory failure\"""""	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2025/03/01	rogid:15Vc5B8nPpFHrwDzDcAWGGZaryk1491	rogid:ETD+5WxItqT0sxuqbQJzqhAPtF89606	intact-crc:24B6FDC448958AC6|rigid:JeZpKGX5O9xYo16ZmgtYY9nNojU	false	sufficient binding region:871-1296|mutation decreasing interaction strength:1294-1294|mutation decreasing interaction strength:1156-1156|mutation decreasing interaction strength:1146-1146,1145-1145	sufficient binding region:456-574|fluorescein-5-maleimide label:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P0DPI0	uniprotkb:Q496J9	intact:EBI-8178893|uniprotkb:P18639|intact:MINT-1795451|uniprotkb:P01561|uniprotkb:A5HZZ9|uniprotkb:A7G1U9|uniprotkb:P10845	intact:EBI-16081469|intact:EBI-28984041|uniprotkb:Q496K1|uniprotkb:Q9UPU8|ensembl:ENSP00000423541.2	psi-mi:bxa1_clobo(display_long)|uniprotkb:botA(gene name)|psi-mi:botA(display_short)|uniprotkb:atx(gene name synonym)|uniprotkb:Bontoxilysin-A(gene name synonym)|uniprotkb:Botulinum neurotoxin type A1(gene name synonym)|uniprotkb:bonT(gene name synonym)	psi-mi:sv2c_human(display_long)|uniprotkb:SV2C(gene name)|psi-mi:SV2C(display_short)|uniprotkb:KIAA1054(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Benoit et al. (2014)	pubmed:24240280|doi:10.1038/nature12732|imex:IM-22354	taxid:1491(clobo)|taxid:1491(Clostridium botulinum)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16081550|imex:IM-22354-3|dip:DIP-195895E	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR012500(Clostridium neurotoxin, translocation)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR036248|refseq:WP_003356619.1|refseq:WP_011948511.1|mint:P0DPI0|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044231""(host cell presynaptic membrane)|go:""GO:0090729""(toxin activity)|go:""GO:1905576""(ganglioside GT1b binding)|rcsb pdb:1XTF|rcsb pdb:1XTG|rcsb pdb:2ILP|rcsb pdb:2IMA|rcsb pdb:2IMB|rcsb pdb:2IMC|rcsb pdb:2ISE|rcsb pdb:2ISG|rcsb pdb:2ISH|rcsb pdb:2VU9|rcsb pdb:2VUA|rcsb pdb:2W2D|rcsb pdb:3BOK|rcsb pdb:3BON|rcsb pdb:3BOO|rcsb pdb:3V0A|rcsb pdb:3V0B|rcsb pdb:3V0C|rcsb pdb:3ZUR|rcsb pdb:3ZUS|rcsb pdb:4HEV|rcsb pdb:4IQP|rcsb pdb:4JRA|rcsb pdb:5JLV|rcsb pdb:5JMC|rcsb pdb:5MK6|rcsb pdb:5MK7|rcsb pdb:5TPB|rcsb pdb:5TPC|rcsb pdb:5V8P|rcsb pdb:5V8R|rcsb pdb:5V8U|rcsb pdb:5VGV|rcsb pdb:5VGX|rcsb pdb:6DKK|rcsb pdb:6MHJ|rcsb pdb:6XCB|rcsb pdb:6XCC|rcsb pdb:6XCD|rcsb pdb:6XCE|rcsb pdb:6XCF|rcsb pdb:7KYF|rcsb pdb:7KYH|rcsb pdb:7LZP|rcsb pdb:7M1H|reactome:R-HSA-5250968"	"refseq:NP_055794.3|refseq:XP_011541583.1|refseq:XP_011541584.2|dip:DIP-60687N|ensembl:ENSG00000122012.14(gene)|ensembl:ENST00000502798.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0098691""(dopaminergic synapse)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR001646(Pentapeptide repeat)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR022308|interpro:IPR036259|rcsb pdb:4JRA|rcsb pdb:5JLV|rcsb pdb:5MOY|rcsb pdb:6ES1|rcsb pdb:7UIA|rcsb pdb:7UIB|reactome:R-HSA-5250955|reactome:R-HSA-5250968|reactome:R-HSA-5250981|panther:PTHR23511(orthology-group)"	"psi-mi:""MI:0465""(dip)"	"comment:mint|function:""\""Inhibits acetylcholine release. The botulinum toxin binds with high affinity to peripheral neuronal presynaptic membrane to the secretory vesicle protein SV2. It binds directly to the largest luminal loop of SV2A, SV2B and SV2C. It is then internalized by receptor-mediated endocytosis. The C-terminus of the heavy chain (H) is responsible for the adherence of the toxin to the cell surface while the N-terminus mediates transport of the light chain from the endocytic vesicle to the cytosol. After translocation, the light chain (L) hydrolyzes the 197-Gln-|-Arg-198 bond in SNAP-25, thereby blocking neurotransmitter release. Inhibition of acetylcholine release results in flaccid paralysis, with frequent heart or respiratory failure\"""""	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2025/03/01	rogid:15Vc5B8nPpFHrwDzDcAWGGZaryk1491	rogid:ETD+5WxItqT0sxuqbQJzqhAPtF89606	intact-crc:A8EC6CC2EE149D91|rigid:JeZpKGX5O9xYo16ZmgtYY9nNojU	false	sufficient binding region:871-1296|mutation decreasing interaction strength:1294-1294|mutation decreasing interaction strength:1156-1156|mutation disrupting interaction strength:1146-1146,1145-1145|his tag:n-n	sufficient binding region:456-574	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q6XZF7-1	uniprotkb:P71451	intact:EBI-16085546|ensembl:ENSP00000315659.4	intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787	psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym)	psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short)	"psi-mi:""MI:0114""(x-ray crystallography)"	Polle et al. (2014)	pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16085554|imex:IM-22320-1|dip:DIP-195811E|pdbe:4CC4	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-2483419(isoform-parent)|ensembl:ENSG00000107554.17(gene)|ensembl:ENST00000324109.9(transcript)|uniprotkb:Q6XZF7-1(isoform-parent)	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR050836|rcsb pdb:1XEU|rcsb pdb:4CC4|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2024/11/14	rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606	rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565	intact-crc:543E3F7DD8A1E123|rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s	false	sufficient binding region:1513-1577	sufficient binding region:35-297	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6XZF7-1	uniprotkb:P71451	intact:EBI-16085546|ensembl:ENSP00000315659.4	intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787	psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym)	psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short)	"psi-mi:""MI:0071""(molecular sieving)"	Polle et al. (2014)	pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16085575|imex:IM-22320-2|dip:DIP-195811E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-2483419(isoform-parent)|ensembl:ENSG00000107554.17(gene)|ensembl:ENST00000324109.9(transcript)|uniprotkb:Q6XZF7-1(isoform-parent)	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR050836|rcsb pdb:1XEU|rcsb pdb:4CC4|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2024/11/14	rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606	rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565	intact-crc:774086ACE78E2E6D|rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s	false	sufficient binding region:1513-1577	sufficient binding region:35-297	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6XZF7-1	uniprotkb:P71451	intact:EBI-16085546|ensembl:ENSP00000315659.4	intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787	psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym)	psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short)	"psi-mi:""MI:0096""(pull down)"	Polle et al. (2014)	pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16085619|imex:IM-22320-4|dip:DIP-195811E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-2483419(isoform-parent)|ensembl:ENSG00000107554.17(gene)|ensembl:ENST00000324109.9(transcript)|uniprotkb:Q6XZF7-1(isoform-parent)	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR050836|rcsb pdb:1XEU|rcsb pdb:4CC4|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2024/11/14	rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606	rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565	intact-crc:AB28D5E09A8EDC57|rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s	false	sufficient binding region:1513-1577|glutathione s tranferase tag:?-?	sufficient binding region:35-297|mutation decreasing interaction strength:146-146	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q6XZF7-1	uniprotkb:P71451	intact:EBI-16085546|ensembl:ENSP00000315659.4	intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787	psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym)	psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Polle et al. (2014)	pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16085678|imex:IM-22320-6|dip:DIP-195811E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-2483419(isoform-parent)|ensembl:ENSG00000107554.17(gene)|ensembl:ENST00000324109.9(transcript)|uniprotkb:Q6XZF7-1(isoform-parent)	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR050836|rcsb pdb:1XEU|rcsb pdb:4CC4|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2024/11/14	rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606	rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565	intact-crc:A59EE36FF36D4796|rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s	false	sufficient binding region:1513-1577	sufficient binding region:35-297|mutation decreasing interaction strength:146-146	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6XZF7-1	uniprotkb:P71451	intact:EBI-16085546|ensembl:ENSP00000315659.4	intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787	psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym)	psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short)	"psi-mi:""MI:0096""(pull down)"	Polle et al. (2014)	pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16085723|imex:IM-22320-8|dip:DIP-195811E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-2483419(isoform-parent)|ensembl:ENSG00000107554.17(gene)|ensembl:ENST00000324109.9(transcript)|uniprotkb:Q6XZF7-1(isoform-parent)	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR050836|rcsb pdb:1XEU|rcsb pdb:4CC4|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2024/11/14	rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606	rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565	intact-crc:ACB728A3B82AF76B|rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s	false	sufficient binding region:1513-1577|glutathione s tranferase tag:?-?|mutation decreasing interaction strength:1521-1521|mutation decreasing interaction strength:1569-1569	sufficient binding region:35-297	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q6XZF7-1	uniprotkb:P71451	intact:EBI-16085546|ensembl:ENSP00000315659.4	intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787	psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym)	psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Polle et al. (2014)	pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16085776|imex:IM-22320-10|dip:DIP-195811E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-2483419(isoform-parent)|ensembl:ENSG00000107554.17(gene)|ensembl:ENST00000324109.9(transcript)|uniprotkb:Q6XZF7-1(isoform-parent)	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR050836|rcsb pdb:1XEU|rcsb pdb:4CC4|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2024/11/14	rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606	rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565	intact-crc:310D155824926FF8|rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s	false	sufficient binding region:1513-1577|mutation decreasing interaction strength:1521-1521|mutation decreasing interaction strength:1569-1569	sufficient binding region:35-297	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5X159	uniprotkb:P62837	intact:EBI-16163300	intact:EBI-347677|ensembl:ENSP00000381717.3|ensembl:ENSP00000381718.4|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6	psi-mi:lubx_legpa(display_long)|uniprotkb:lubX(gene name)|psi-mi:lubX(display_short)|uniprotkb:Legionella U-box protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LubX(gene name synonym)|uniprotkb:lpp2887(locus name)	"psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 2""(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D2""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)"	"psi-mi:""MI:0114""(x-ray crystallography)"	Quaile et al. (2015)	pubmed:26146184|doi:10.1016/j.str.2015.05.020|imex:IM-24772	"taxid:297246(legpa)|taxid:297246(""Legionella pneumophila (strain Paris)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16163321|imex:IM-24772-1|dip:DIP-199696E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-61711N|rcsb pdb:4WZ0|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043657""(host cell)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0071218""(cellular response to misfolded protein)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:4WZ2|rcsb pdb:4WZ3|rcsb pdb:4XI1"	"ensembl:ENSG00000131508.17(gene)|ensembl:ENST00000398733.8(transcript)|ensembl:ENST00000398734.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036211""(protein modification process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|rcsb pdb:7R71|rcsb pdb:8B3I|rcsb pdb:8GBQ|rcsb pdb:8GCB|rcsb pdb:8GRM|rcsb pdb:8JWJ|rcsb pdb:8JWU|rcsb pdb:8VK8|rcsb pdb:8VK9|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|panther:PTHR24068(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2025/01/19	rogid:uBAwbxWsn2PQAeQHbPRcaLi/Ftg297246	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:F90E439028B873D6|rigid:uhTK6AZdK+j2ZREPRPfga4z6Y7Y	false	sufficient binding region:1-215	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8N4S9	uniprotkb:Q48UF7	intact:EBI-6875061|ensembl:ENSP00000323264.5|ensembl:ENSP00000480044.1|ensembl:ENSP00000480068.1|ensembl:ENSP00000494616.1|uniprotkb:A1BQX0|uniprotkb:A1BQX1|uniprotkb:A8KA97|uniprotkb:Q96NM9	intact:EBI-16745417	psi-mi:mald2_human(display_long)|uniprotkb:MARVELD2(gene name)|psi-mi:MARVELD2(display_short)|uniprotkb:TRIC(gene name synonym)|uniprotkb:Tricellulin(gene name synonym)	psi-mi:eno_strpm(display_long)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:M28_Spy0535(locus name)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Sumitomo et al. (2016)	pubmed:26822058|imex:IM-26330	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:319701(""Streptococcus pyogenes serotype M28 (strain MGAS6180)"")|taxid:319701(""Streptococcus pyogenes serotype M28 (strain MGAS6180)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-16745396|imex:IM-26330-3	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:90636""|ensembl:ENSG00000152939.17(gene)|ensembl:ENSG00000274671.4(gene)|ensembl:ENST00000325631.10(transcript)|ensembl:ENST00000614617.4(transcript)|ensembl:ENST00000622835.4(transcript)|ensembl:ENST00000645446.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030054""(cell junction)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0033010""(paranodal junction)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0061028""(establishment of endothelial barrier)|go:""GO:0061689""(tricellular tight junction)|go:""GO:0070160""(tight junction)|go:""GO:0070830""(bicellular tight junction assembly)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|mint:Q8N4S9|rcsb pdb:5N7H|rcsb pdb:5N7I|rcsb pdb:5N7K|refseq:NP_001033692.2|refseq:NP_001231663.1|refseq:XP_005248502.1|refseq:XP_005248503.1|refseq:XP_005248504.1|panther:PTHR23288(orthology-group)"	"go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006096""(glycolytic process)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0009986""(cell surface)|interpro:IPR036849|interpro:IPR029017|interpro:IPR000941(Enolase)|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|refseq:WP_002985288.1"	-	-	-	figure legend:Figs. 3, 5C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/17	2024/11/14	rogid:WBHGueJq4y54+epedLVPcMvhhOU9606	rogid:2jU4pZ3SLooiUOTV1qy972OkQMM319701	intact-crc:E42BB20F5F671019|rigid:+9RzuB9K+4JYjyDwDIkkWPTI9Q8	false	his tag:?-?|sufficient binding region:216-254|mutation decreasing interaction strength:252-252|mutation disrupting interaction strength:217-217,252-252|mutation decreasing interaction strength:217-217	his tag:n-n	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P00747	uniprotkb:Q48UF7	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-16745417	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:eno_strpm(display_long)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:M28_Spy0535(locus name)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)	"psi-mi:""MI:0049""(filter binding)"	Sumitomo et al. (2016)	pubmed:26822058|imex:IM-26330	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:319701(""Streptococcus pyogenes serotype M28 (strain MGAS6180)"")|taxid:319701(""Streptococcus pyogenes serotype M28 (strain MGAS6180)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-16745462|imex:IM-26330-5	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006096""(glycolytic process)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0009986""(cell surface)|interpro:IPR036849|interpro:IPR029017|interpro:IPR000941(Enolase)|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|refseq:WP_002985288.1"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/01/17	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:2jU4pZ3SLooiUOTV1qy972OkQMM319701	intact-crc:CD38278D13332AC8|rigid:HWKmiJl+WkrIyXiF2/6gWHRJWJA	false	-	his tag:n-n	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q8Z6A7	uniprotkb:O00592	intact:EBI-16063943|uniprotkb:Q7CAE0	intact:EBI-6897823|uniprotkb:A6NHX8|uniprotkb:Q52LZ7|uniprotkb:Q53ER6|ensembl:ENSP00000367817.3	psi-mi:cdtb_salti(display_long)|uniprotkb:cdtB(gene name)|psi-mi:cdtB(display_short)|uniprotkb:Deoxyribonuclease CdtB(gene name synonym)|uniprotkb:STY1886(locus name)|uniprotkb:t1111(locus name)	psi-mi:podxl_human(display_long)|uniprotkb:PODXL(gene name)|psi-mi:PODXL(display_short)|uniprotkb:PCLP(gene name synonym)|uniprotkb:PCLP1(gene name synonym)|uniprotkb:GCTM-2 antigen(gene name synonym)|uniprotkb:Gp200(gene name synonym)|uniprotkb:Podocalyxin-like protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Song et al. (2013)	pubmed:23842500|doi:10.1038/nature12377|imex:IM-21257	taxid:90370(salti)|taxid:90370(Salmonella typhi)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16063961|imex:IM-21257-1|dip:DIP-191210E	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001529135.1|dip:DIP-60315N|refseq:NP_456275.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0005576""(extracellular region)|go:""GO:0090729""(toxin activity)|interpro:IPR003539(Cytolethal distending toxin B)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|rcsb pdb:4K6L|rcsb pdb:6VX4"	"efo:""Orphanet:2828""|efo:""Orphanet:391411""|ensembl:ENSG00000128567.17(gene)|ensembl:ENST00000378555.8(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0005615""(extracellular space)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030027""(lamellipodium)|go:""GO:0030175""(filopodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032534""(regulation of microvillus assembly)|go:""GO:0033634""(positive regulation of cell-cell adhesion mediated by integrin)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036057""(slit diaphragm)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045121""(membrane raft)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072015""(podocyte development)|go:""GO:0072175""(epithelial tube formation)|interpro:IPR013836(CD34/Podocalyxin)|interpro:IPR017403(Podocalyxin-like protein 1)|refseq:NP_001018121.1|refseq:NP_005388.2|dip:DIP-58638N|panther:PTHR12067(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2025/02/28	rogid:1Sv/QxAFuJcYDh4ODMTjOtdZTWw90370	rogid:C1d8Jqj907mNtlSHPasQ7UjD7wM9606	intact-crc:781E3DDD9D5F1100|rigid:M8eZ6VTzCfQH0UhQRRln3p3MUoY	false	sufficient binding region:23-269|flag tag:c-c	-	-	-	"psi-mi:""MI:0032""(de novo protein sequencing by mass spectrometry)"	"psi-mi:""MI:0032""(de novo protein sequencing by mass spectrometry)"
uniprotkb:A5JGM8	uniprotkb:P21579	intact:EBI-16067725	intact:EBI-524909|ensembl:ENSP00000261205.4|ensembl:ENSP00000376932.3|ensembl:ENSP00000447575.1|ensembl:ENSP00000515993.1|ensembl:ENSP00000515997.1|ensembl:ENSP00000515999.1|ensembl:ENSP00000516001.1|ensembl:ENSP00000516002.1|ensembl:ENSP00000516003.1|ensembl:ENSP00000516005.1|ensembl:ENSP00000516007.1|ensembl:ENSP00000516009.1|ensembl:ENSP00000516013.1|uniprotkb:Q6AI31	psi-mi:a5jgm8_clobo(display_long)|uniprotkb:bont(gene name)|psi-mi:bont(display_short)|uniprotkb:boNT D(gene name synonym)|uniprotkb:C(gene name synonym)|uniprotkb:DC(gene name synonym)|uniprotkb:NT(gene name synonym)	psi-mi:syt1_human(display_long)|uniprotkb:Synaptotagmin I(gene name synonym)|uniprotkb:p65(gene name synonym)|uniprotkb:SYT1(gene name)|psi-mi:SYT1(display_short)|uniprotkb:SYT(gene name synonym)|uniprotkb:SVP65(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Berntsson et al. (2013)	pubmed:23932591|doi:10.1016/j.str.2013.06.026|imex:IM-21900	taxid:1491(clobo)|taxid:1491(Clostridium botulinum)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16067807|imex:IM-21900-3|dip:DIP-192444E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-60561N|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0090729""(toxin activity)|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR012500(Clostridium neurotoxin, translocation)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR036248|rcsb pdb:5LR0"	"ensembl:ENSG00000067715.15(gene)|ensembl:ENST00000261205.9(transcript)|ensembl:ENST00000393240.7(transcript)|ensembl:ENST00000552744.5(transcript)|ensembl:ENST00000704696.1(transcript)|ensembl:ENST00000704700.1(transcript)|ensembl:ENST00000704702.1(transcript)|ensembl:ENST00000704704.1(transcript)|ensembl:ENST00000704705.1(transcript)|ensembl:ENST00000704706.1(transcript)|ensembl:ENST00000704708.1(transcript)|ensembl:ENST00000704710.1(transcript)|ensembl:ENST00000704714.1(transcript)|ensembl:ENST00000704718.1(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005513""(detection of calcium ion)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006906""(vesicle fusion)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007269""(neurotransmitter secretion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008289""(lipid binding)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016050""(vesicle organization)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0017158""(regulation of calcium ion-dependent exocytosis)|go:""GO:0030154""(cell differentiation)|go:""GO:0030276""(clathrin binding)|go:""GO:0030348""(syntaxin-3 binding)|go:""GO:0030424""(axon)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031045""(dense core granule)|go:""GO:0033603""(positive regulation of dopamine secretion)|go:""GO:0042584""(chromaffin granule membrane)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048278""(vesicle docking)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0050806""(positive regulation of synaptic transmission)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0051966""(regulation of synaptic transmission, glutamatergic)|go:""GO:0060076""(excitatory synapse)|go:""GO:0060201""(clathrin-sculpted acetylcholine transport vesicle membrane)|go:""GO:0060203""(clathrin-sculpted glutamate transport vesicle membrane)|go:""GO:0061202""(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:""GO:0061669""(spontaneous neurotransmitter secretion)|go:""GO:0061891""(calcium ion sensor activity)|go:""GO:0070083""(clathrin-sculpted monoamine transport vesicle membrane)|go:""GO:0070382""(exocytic vesicle)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:0071911""(synchronous neurotransmitter secretion)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098746""(fast, calcium ion-dependent exocytosis of neurotransmitter)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099502""(calcium-dependent activation of synaptic vesicle fusion)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|go:""GO:1903235""(positive regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:""GO:1903305""(regulation of regulated secretory pathway)|go:""GO:1903861""(positive regulation of dendrite extension)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR035892|mint:P21579|rcsb pdb:2K45|rcsb pdb:2K4A|rcsb pdb:2K8M|rcsb pdb:2KI6|rcsb pdb:2LHA|rcsb pdb:2N1T|rcsb pdb:2R83|rcsb pdb:3F00|rcsb pdb:3F01|rcsb pdb:3F04|rcsb pdb:3F05|rcsb pdb:4ISQ|rcsb pdb:4V11|rcsb pdb:6G5F|rcsb pdb:6G5K|rcsb pdb:6QNS|rcsb pdb:6TZ3|rcsb pdb:6U41|rcsb pdb:6U4U|rcsb pdb:6U4W|rcsb pdb:6ZVN|rcsb pdb:7TUA|rcsb pdb:7U4Q|rcsb pdb:8B8I|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-5250958|reactome:R-HSA-5250989|reactome:R-HSA-6794361|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|refseq:NP_001129277.1|refseq:NP_001129278.1|refseq:NP_005630.1|refseq:XP_011537012.1|refseq:XP_016875398.1|dip:DIP-34042N|efo:""Orphanet:522077""|panther:PTHR10024(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2025/01/27	rogid:OreS102Dko4/mgYvmRiUYvkQZqk1491	rogid:oWQJLjUokM2dCvvO+VHVbHUj/WE9606	intact-crc:6B2DF4C8DF7A7D04|rigid:FYHyBM5JRu7cCi/DuZUqQC1YeHw	false	sufficient binding region:859-1285	sufficient binding region:33-53	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UI21	uniprotkb:Q15628	intact:EBI-16070376	intact:EBI-359215|uniprotkb:Q52NZ1|uniprotkb:B2RDS3|uniprotkb:B3KQZ9|ensembl:ENSP00000341268.4	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:tradd_human(display_long)|uniprotkb:TRADD(gene name)|psi-mi:TRADD(display_short)|uniprotkb:TNFRSF1A-associated via death domain(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Li et al. (2013)	pubmed:23955153|doi:10.1038/nature12436|imex:IM-21832	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16070384|imex:IM-21832-2|dip:DIP-192228E	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"panther:PTHR14913(orthology-group)|refseq:NP_003780.1|refseq:NP_001310481.1|refseq:XP_005256270.1|refseq:XP_016879304.1|dip:DIP-285N|ensembl:ENSG00000102871.16(gene)|ensembl:ENST00000345057.9(transcript)|go:""GO:0002947""(tumor necrosis factor receptor superfamily complex)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051798""(positive regulation of hair follicle development)|go:""GO:0070513""(death domain binding)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR009095(TRADD, N-terminal)|interpro:IPR011029(DEATH-like)|interpro:IPR035712|interpro:IPR036729|mint:Q15628|rcsb pdb:1F2H|rcsb pdb:1F3V|rcsb pdb:5XME|rcsb pdb:6AC0|rcsb pdb:7CSQ|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9693928"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2017/08/07	2025/03/26	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:waTMnn0uXSbf7bracJUScX9ckEc9606	intact-crc:19CADF65210A036D|rigid:h8gI1MgXbpl6MJuwFXU28N1njI4	false	-	sufficient binding region:195-312	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UI21	uniprotkb:Q15628	intact:EBI-16070376	intact:EBI-359215|uniprotkb:Q52NZ1|uniprotkb:B2RDS3|uniprotkb:B3KQZ9|ensembl:ENSP00000341268.4	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:tradd_human(display_long)|uniprotkb:TRADD(gene name)|psi-mi:TRADD(display_short)|uniprotkb:TNFRSF1A-associated via death domain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Li et al. (2013)	pubmed:23955153|doi:10.1038/nature12436|imex:IM-21832	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16070446|imex:IM-21832-5|dip:DIP-192228E	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"panther:PTHR14913(orthology-group)|refseq:NP_003780.1|refseq:NP_001310481.1|refseq:XP_005256270.1|refseq:XP_016879304.1|dip:DIP-285N|ensembl:ENSG00000102871.16(gene)|ensembl:ENST00000345057.9(transcript)|go:""GO:0002947""(tumor necrosis factor receptor superfamily complex)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051798""(positive regulation of hair follicle development)|go:""GO:0070513""(death domain binding)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR009095(TRADD, N-terminal)|interpro:IPR011029(DEATH-like)|interpro:IPR035712|interpro:IPR036729|mint:Q15628|rcsb pdb:1F2H|rcsb pdb:1F3V|rcsb pdb:5XME|rcsb pdb:6AC0|rcsb pdb:7CSQ|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9693928"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/26	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:waTMnn0uXSbf7bracJUScX9ckEc9606	intact-crc:F1098BB8C5F12F81|rigid:h8gI1MgXbpl6MJuwFXU28N1njI4	false	ha tag:n-n	flag tag:n-n|ha tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q15628	uniprotkb:B7UI21	intact:EBI-359215|uniprotkb:Q52NZ1|uniprotkb:B2RDS3|uniprotkb:B3KQZ9|ensembl:ENSP00000341268.4	intact:EBI-16070376	psi-mi:tradd_human(display_long)|uniprotkb:TRADD(gene name)|psi-mi:TRADD(display_short)|uniprotkb:TNFRSF1A-associated via death domain(gene name synonym)	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Li et al. (2013)	pubmed:23955153|doi:10.1038/nature12436|imex:IM-21832	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16070540|imex:IM-21832-9|dip:DIP-192231E	intact-miscore:0.68	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR14913(orthology-group)|refseq:NP_003780.1|refseq:NP_001310481.1|refseq:XP_005256270.1|refseq:XP_016879304.1|dip:DIP-285N|ensembl:ENSG00000102871.16(gene)|ensembl:ENST00000345057.9(transcript)|go:""GO:0002947""(tumor necrosis factor receptor superfamily complex)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051798""(positive regulation of hair follicle development)|go:""GO:0070513""(death domain binding)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR009095(TRADD, N-terminal)|interpro:IPR011029(DEATH-like)|interpro:IPR035712|interpro:IPR036729|mint:Q15628|rcsb pdb:1F2H|rcsb pdb:1F3V|rcsb pdb:5XME|rcsb pdb:6AC0|rcsb pdb:7CSQ|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9693928"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/26	rogid:waTMnn0uXSbf7bracJUScX9ckEc9606	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	intact-crc:E424504876109A9C|rigid:q1D6U2jwpjhp0lcY4WCR5QvO62I	false	flag tag:n-n	enhanced green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B7UI21	uniprotkb:Q15628	intact:EBI-16070376	intact:EBI-359215|uniprotkb:Q52NZ1|uniprotkb:B2RDS3|uniprotkb:B3KQZ9|ensembl:ENSP00000341268.4	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:tradd_human(display_long)|uniprotkb:TRADD(gene name)|psi-mi:TRADD(display_short)|uniprotkb:TNFRSF1A-associated via death domain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Li et al. (2013)	pubmed:23955153|doi:10.1038/nature12436|imex:IM-21832	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16070515|imex:IM-21832-8|dip:DIP-192228E	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"panther:PTHR14913(orthology-group)|refseq:NP_003780.1|refseq:NP_001310481.1|refseq:XP_005256270.1|refseq:XP_016879304.1|dip:DIP-285N|ensembl:ENSG00000102871.16(gene)|ensembl:ENST00000345057.9(transcript)|go:""GO:0002947""(tumor necrosis factor receptor superfamily complex)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051798""(positive regulation of hair follicle development)|go:""GO:0070513""(death domain binding)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR009095(TRADD, N-terminal)|interpro:IPR011029(DEATH-like)|interpro:IPR035712|interpro:IPR036729|mint:Q15628|rcsb pdb:1F2H|rcsb pdb:1F3V|rcsb pdb:5XME|rcsb pdb:6AC0|rcsb pdb:7CSQ|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9693928"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/26	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:waTMnn0uXSbf7bracJUScX9ckEc9606	intact-crc:06DB0B80AA1334AB|rigid:h8gI1MgXbpl6MJuwFXU28N1njI4	false	enhanced green fluorescent protein tag:n-n	sufficient binding region:195-312|flag tag:n-n|necessary binding region:195-312	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:B7UI21	uniprotkb:Q15628	intact:EBI-16070376	intact:EBI-359215|uniprotkb:Q52NZ1|uniprotkb:B2RDS3|uniprotkb:B3KQZ9|ensembl:ENSP00000341268.4	psi-mi:nleb1_eco27(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:nleB(gene name synonym)|uniprotkb:E2348C_3231(locus name)	psi-mi:tradd_human(display_long)|uniprotkb:TRADD(gene name)|psi-mi:TRADD(display_short)|uniprotkb:TNFRSF1A-associated via death domain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Li et al. (2013)	pubmed:23955153|doi:10.1038/nature12436|imex:IM-21832	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16070562|imex:IM-21832-10|dip:DIP-192228E	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_012578998.1|dip:DIP-60511N|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0034054""(obsolete symbiont-mediated suppression of host defense-related programmed cell death)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6ACI|rcsb pdb:6E66"	"panther:PTHR14913(orthology-group)|refseq:NP_003780.1|refseq:NP_001310481.1|refseq:XP_005256270.1|refseq:XP_016879304.1|dip:DIP-285N|ensembl:ENSG00000102871.16(gene)|ensembl:ENST00000345057.9(transcript)|go:""GO:0002947""(tumor necrosis factor receptor superfamily complex)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051798""(positive regulation of hair follicle development)|go:""GO:0070513""(death domain binding)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR009095(TRADD, N-terminal)|interpro:IPR011029(DEATH-like)|interpro:IPR035712|interpro:IPR036729|mint:Q15628|rcsb pdb:1F2H|rcsb pdb:1F3V|rcsb pdb:5XME|rcsb pdb:6AC0|rcsb pdb:7CSQ|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9693928"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2025/03/26	rogid:xbfOIuSfSXVHLS0Pvfcy1zeoxA8574521	rogid:waTMnn0uXSbf7bracJUScX9ckEc9606	intact-crc:52AD3CB3E7FB41E8|rigid:h8gI1MgXbpl6MJuwFXU28N1njI4	false	flag tag:n-n|mutation disrupting interaction strength:223-223,221-221	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P62837	uniprotkb:A0A0H2USG1	intact:EBI-347677|ensembl:ENSP00000381717.3|ensembl:ENSP00000381718.4|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6	intact:EBI-16359037	"psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 2""(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D2""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)"	psi-mi:ipa14_shifl(display_long)|uniprotkb:CP0265(locus name)|uniprotkb:ipaH1.4(gene name)|psi-mi:ipaH1.4(display_short)|uniprotkb:Invasion plasmid antigen 1.4(gene name synonym)|uniprotkb:SF_p0265(orf name)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Singer et al. (2008)	pubmed:18997778|doi:10.1038/nsmb.1511|imex:IM-9610	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16222098|imex:IM-9610-3|dip:DIP-88307E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000131508.17(gene)|ensembl:ENST00000398733.8(transcript)|ensembl:ENST00000398734.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036211""(protein modification process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|rcsb pdb:7R71|rcsb pdb:8B3I|rcsb pdb:8GBQ|rcsb pdb:8GCB|rcsb pdb:8GRM|rcsb pdb:8JWJ|rcsb pdb:8JWU|rcsb pdb:8VK8|rcsb pdb:8VK9|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|panther:PTHR24068(orthology-group)"	"refseq:WP_000597731.1|rcsb pdb:3CKD|rcsb pdb:7YA7|interpro:IPR032675|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032674|interpro:IPR029487|refseq:NP_858398.2|rcsb pdb:7V8E|rcsb pdb:7V8G|rcsb pdb:7V8H|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|interpro:IPR051071"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/09	2025/01/19	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:Mblp501VtVUW3gfvGtZbdPspxgI623	intact-crc:9C9B50A5528F70EC|rigid:DHGCjspot5iH/+lMeZCWfxRjq4s	false	fluorescent dye label:?-?	binding-associated region:265-575	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8VSC3	uniprotkb:P62837	intact:EBI-6125799|uniprotkb:O85159|uniprotkb:Q2TH74|uniprotkb:Q6XVV1|uniprotkb:Q9AFM5|uniprotkb:Q9AJV1	intact:EBI-347677|ensembl:ENSP00000381717.3|ensembl:ENSP00000381718.4|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6	psi-mi:ipa9_shifl(display_long)|uniprotkb:ipaH9.8(gene name)|psi-mi:ipaH9.8(display_short)|uniprotkb:Invasion plasmid antigen 9.8(gene name synonym)|uniprotkb:SFLP090(orf name)|uniprotkb:pWR501_0234(orf name)|uniprotkb:CP0226(locus name)	"psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 2""(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D2""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Singer et al. (2008)	pubmed:18997778|doi:10.1038/nsmb.1511|imex:IM-9610	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16222119|imex:IM-9610-4|dip:DIP-88306E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_858359.2|refseq:YP_006960318.1|mint:Q8VSC3|dip:DIP-46341N|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0042025""(host cell nucleus)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044314""(protein K27-linked ubiquitination)|go:""GO:0044414""(symbiont-mediated suppression of host defenses)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0052036""(symbiont-mediated suppression of host inflammatory response)|go:""GO:0052170""(symbiont-mediated suppression of host innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|interpro:IPR051071|rcsb pdb:3L3P|rcsb pdb:5B0N|rcsb pdb:5B0T|rcsb pdb:6K2D|rcsb pdb:6LOJ|rcsb pdb:6LOL"	"ensembl:ENSG00000131508.17(gene)|ensembl:ENST00000398733.8(transcript)|ensembl:ENST00000398734.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036211""(protein modification process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|rcsb pdb:7R71|rcsb pdb:8B3I|rcsb pdb:8GBQ|rcsb pdb:8GCB|rcsb pdb:8GRM|rcsb pdb:8JWJ|rcsb pdb:8JWU|rcsb pdb:8VK8|rcsb pdb:8VK9|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|panther:PTHR24068(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/09	2025/01/19	rogid:vkGhHfT9QMT1xPHgaxaJ0dFaYZw623	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:4BE30496B31780EA|rigid:jZwAfAXfzsdeoPSybC4k18X1zCk	false	binding-associated region:208-545|glutathione s tranferase tag:n-n	his tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0H2USG1	intact:EBI-4399559	intact:EBI-16359037	dip:DIP-24261N	psi-mi:ipa14_shifl(display_long)|uniprotkb:CP0265(locus name)|uniprotkb:ipaH1.4(gene name)|psi-mi:ipaH1.4(display_short)|uniprotkb:Invasion plasmid antigen 1.4(gene name synonym)|uniprotkb:SF_p0265(orf name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	"psi-mi:""MI:0808""(comigration in sds page)"	Singer et al. (2008)	pubmed:18997778|doi:10.1038/nsmb.1511|imex:IM-9610	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16222060|imex:IM-9610-1|dip:DIP-88304E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000597731.1|rcsb pdb:3CKD|rcsb pdb:7YA7|interpro:IPR032675|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032674|interpro:IPR029487|refseq:NP_858398.2|rcsb pdb:7V8E|rcsb pdb:7V8G|rcsb pdb:7V8H|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|go:""GO:0090729""(toxin activity)|interpro:IPR051071"	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	"psi-mi:""MI:0465""(dip)"	-	no-uniprot-update:	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/09	2024/11/14	rogid:Mblp501VtVUW3gfvGtZbdPspxgI623	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	intact-crc:42275820F9C5BB6E|rigid:khvW1PtDAIeWRmOchK8Y9eSsGqw	false	sufficient binding region:265-575	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-4399559	uniprotkb:Q8VSC3	dip:DIP-24261N	intact:EBI-6125799|uniprotkb:O85159|uniprotkb:Q2TH74|uniprotkb:Q6XVV1|uniprotkb:Q9AFM5|uniprotkb:Q9AJV1	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:ipa9_shifl(display_long)|uniprotkb:ipaH9.8(gene name)|psi-mi:ipaH9.8(display_short)|uniprotkb:Invasion plasmid antigen 9.8(gene name synonym)|uniprotkb:SFLP090(orf name)|uniprotkb:pWR501_0234(orf name)|uniprotkb:CP0226(locus name)	"psi-mi:""MI:0808""(comigration in sds page)"	Singer et al. (2008)	pubmed:18997778|doi:10.1038/nsmb.1511|imex:IM-9610	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16222079|imex:IM-9610-2|dip:DIP-88305E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	"refseq:NP_858359.2|refseq:YP_006960318.1|mint:Q8VSC3|dip:DIP-46341N|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0042025""(host cell nucleus)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044314""(protein K27-linked ubiquitination)|go:""GO:0044414""(symbiont-mediated suppression of host defenses)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0052036""(symbiont-mediated suppression of host inflammatory response)|go:""GO:0052170""(symbiont-mediated suppression of host innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0085034""(symbiont-mediated suppression of host NF-kappaB cascade)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|interpro:IPR051071|rcsb pdb:3L3P|rcsb pdb:5B0N|rcsb pdb:5B0T|rcsb pdb:6K2D|rcsb pdb:6LOJ|rcsb pdb:6LOL"	"psi-mi:""MI:0465""(dip)"	no-uniprot-update:	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/09	2024/11/14	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:vkGhHfT9QMT1xPHgaxaJ0dFaYZw623	intact-crc:A32B66ABEF0950C2|rigid:xpoz4LDZs7VTtCiNkmqhACXgpHk	false	-	sufficient binding region:208-545	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P02671	uniprotkb:Q99XV0	intact:EBI-348571|uniprotkb:Q9BX62|uniprotkb:Q9UCH2|uniprotkb:A8K3E4|ensembl:ENSP00000498441.1|uniprotkb:Q4QQH7|uniprotkb:D3DP14|uniprotkb:D3DP15	intact:EBI-16359063	psi-mi:fiba_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short)	psi-mi:q99xv0_strp1(display_long)|uniprotkb:emm1(gene name)|psi-mi:emm1(display_short)|uniprotkb:SPy_2018(locus name)	"psi-mi:""MI:0114""(x-ray crystallography)"	Macheboeuf et al. (2011)	pubmed:21475196|doi:10.1038/nature09967|imex:IM-16225	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16223006|imex:IM-16225-1|dip:DIP-187266E	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"reactome:R-HSA-216083|ensembl:ENSG00000171560.18(gene)|ensembl:ENST00000651975.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043152""(induction of bacterial agglutination)|go:""GO:0045087""(innate immune response)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0046872""(metal ion binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051258""(protein polymerization)|go:""GO:0051592""(response to calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0072377""(blood coagulation, common pathway)|go:""GO:0072378""(blood coagulation, fibrin clot formation)|go:""GO:0072562""(blood microparticle)|go:""GO:0090277""(positive regulation of peptide hormone secretion)|reactome:R-HSA-354192|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903561""(extracellular vesicle)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR021996|interpro:IPR036056|interpro:IPR037579|mint:P02671|rcsb pdb:1BBR|rcsb pdb:1DM4|rcsb pdb:1FPH|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZD|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:1YCP|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3AT0|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4F27|rcsb pdb:5CFA|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-977225|refseq:NP_000499.1|refseq:NP_068657.1|dip:DIP-29643N|efo:""Orphanet:101041""|efo:""Orphanet:248408""|efo:""Orphanet:93562""|efo:""Orphanet:98880""|efo:""Orphanet:98881""|panther:PTHR47221(orthology-group)"	"interpro:IPR019950|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR019931|interpro:IPR049895|interpro:IPR049896|refseq:NP_269973.1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/09	2025/03/26	rogid:khlQGVpd+6qZLTrsT9KxlxgjMR09606	rogid:dk0fxAr9YZ09sJSvv0MLdX75zpY301447	intact-crc:0234CE1E523F80AD|rigid:eWfUInt+O/d/phTtEmKFgO2bGZw	false	binding-associated region:130-216	binding-associated region:128-263|binding-associated region:42-132	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02671	uniprotkb:Q99XV0	intact:EBI-348571|uniprotkb:Q9BX62|uniprotkb:Q9UCH2|uniprotkb:A8K3E4|ensembl:ENSP00000498441.1|uniprotkb:Q4QQH7|uniprotkb:D3DP14|uniprotkb:D3DP15	intact:EBI-16359063	psi-mi:fiba_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short)	psi-mi:q99xv0_strp1(display_long)|uniprotkb:emm1(gene name)|psi-mi:emm1(display_short)|uniprotkb:SPy_2018(locus name)	"psi-mi:""MI:0071""(molecular sieving)"	Macheboeuf et al. (2011)	pubmed:21475196|doi:10.1038/nature09967|imex:IM-16225	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-16223035|imex:IM-16225-2|dip:DIP-187266E	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"reactome:R-HSA-216083|ensembl:ENSG00000171560.18(gene)|ensembl:ENST00000651975.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043152""(induction of bacterial agglutination)|go:""GO:0045087""(innate immune response)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0046872""(metal ion binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051258""(protein polymerization)|go:""GO:0051592""(response to calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0072377""(blood coagulation, common pathway)|go:""GO:0072378""(blood coagulation, fibrin clot formation)|go:""GO:0072562""(blood microparticle)|go:""GO:0090277""(positive regulation of peptide hormone secretion)|reactome:R-HSA-354192|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903561""(extracellular vesicle)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR021996|interpro:IPR036056|interpro:IPR037579|mint:P02671|rcsb pdb:1BBR|rcsb pdb:1DM4|rcsb pdb:1FPH|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZD|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:1YCP|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3AT0|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4F27|rcsb pdb:5CFA|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-977225|refseq:NP_000499.1|refseq:NP_068657.1|dip:DIP-29643N|efo:""Orphanet:101041""|efo:""Orphanet:248408""|efo:""Orphanet:93562""|efo:""Orphanet:98880""|efo:""Orphanet:98881""|panther:PTHR47221(orthology-group)"	"interpro:IPR019950|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR019931|interpro:IPR049895|interpro:IPR049896|refseq:NP_269973.1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/09	2025/03/26	rogid:khlQGVpd+6qZLTrsT9KxlxgjMR09606	rogid:dk0fxAr9YZ09sJSvv0MLdX75zpY301447	intact-crc:9B8634CEF7F4F1CA|rigid:eWfUInt+O/d/phTtEmKFgO2bGZw	false	binding-associated region:130-216	binding-associated region:128-263|binding-associated region:42-132	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6X1Y7	uniprotkb:P62820-1	intact:EBI-15666803	intact:EBI-15666813|uniprotkb:P11476-1|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:q6x1y7_legpn(display_long)|uniprotkb:lepB(gene name)|psi-mi:lepB(display_short)|uniprotkb:JBJ86_15280(orf name)	psi-mi:p62820-1(display_long)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)|uniprotkb:YPT1-related protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Ingmundson et al. (2007)	pubmed:17952054|doi:10.1038/nature06336|imex:IM-21330	taxid:446(legpn)|taxid:446(Legionella pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15666822|imex:IM-21330-1|dip:DIP-191503E	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_010948192.1|dip:DIP-60362N|go:""GO:0016020""(membrane)|interpro:IPR040484|interpro:IPR040519|interpro:IPR041585|rcsb pdb:4JW1"	intact:EBI-716845(isoform-parent)|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2024/11/14	rogid:9Eok8GTspDcE6F+y9iArZYGArc8446	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:33E1233E80DCB144|rigid:LCk4tBRYafiSMjmUGVV6G3LpC4U	false	green fluorescent protein tag:n-n	mutation increasing interaction strength:70-70|glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6X1Y7	uniprotkb:P62820-1	intact:EBI-15666803	intact:EBI-15666813|uniprotkb:P11476-1|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:q6x1y7_legpn(display_long)|uniprotkb:lepB(gene name)|psi-mi:lepB(display_short)|uniprotkb:JBJ86_15280(orf name)	psi-mi:p62820-1(display_long)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)|uniprotkb:YPT1-related protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Ingmundson et al. (2007)	pubmed:17952054|doi:10.1038/nature06336|imex:IM-21330	taxid:446(legpn)|taxid:446(Legionella pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15666848|imex:IM-21330-2|dip:DIP-191503E	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_010948192.1|dip:DIP-60362N|go:""GO:0016020""(membrane)|interpro:IPR040484|interpro:IPR040519|interpro:IPR041585|rcsb pdb:4JW1"	intact:EBI-716845(isoform-parent)|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2024/11/14	rogid:9Eok8GTspDcE6F+y9iArZYGArc8446	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:B7BA6F61806CF391|rigid:LCk4tBRYafiSMjmUGVV6G3LpC4U	false	his tag:n-n	mutation increasing interaction strength:70-70|glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8ZNR3	intact:EBI-4399559	intact:EBI-15674008	dip:DIP-24261N	psi-mi:sopa_salty(display_long)|uniprotkb:sopA(gene name)|psi-mi:sopA(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase SopA(gene name synonym)|uniprotkb:Salmonella outer protein A(gene name synonym)|uniprotkb:Secreted effector protein SopA(gene name synonym)|uniprotkb:STM2066(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	"psi-mi:""MI:0808""(comigration in sds page)"	Diao et al. (2008)	pubmed:18066077|doi:10.1038/nsmb1346|imex:IM-9647	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15674032|imex:IM-9647-1|dip:DIP-88385E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_461011.1|dip:DIP-46397N|refseq:WP_000703998.1|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043657""(host cell)|interpro:IPR025725|interpro:IPR025726|interpro:IPR038270|rcsb pdb:2QYU|rcsb pdb:2QZA|rcsb pdb:3SY2|rcsb pdb:5JW7|rcsb pdb:8ST8"	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	"psi-mi:""MI:0465""(dip)"	crc64:1D56B53EC05EDB94	no-uniprot-update:	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2024/11/14	rogid:HVE7zb36Q3b9GAfYxyunpbGI89M99287	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	intact-crc:19260496AD53F2C9|rigid:/vGZNLwwd0cBTe81uI3JIEhI/o8	false	glutathione s tranferase tag:n-n|sufficient binding region:470-782	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q8ZNR3	uniprotkb:P68036-1	intact:EBI-15674008	intact:EBI-15556257|ensembl:ENSP00000344259.5	psi-mi:sopa_salty(display_long)|uniprotkb:sopA(gene name)|psi-mi:sopA(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase SopA(gene name synonym)|uniprotkb:Salmonella outer protein A(gene name synonym)|uniprotkb:Secreted effector protein SopA(gene name synonym)|uniprotkb:STM2066(locus name)	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Diao et al. (2008)	pubmed:18066077|doi:10.1038/nsmb1346|imex:IM-9647	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15674053|imex:IM-9647-2|dip:DIP-88386E	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_461011.1|dip:DIP-46397N|refseq:WP_000703998.1|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043657""(host cell)|interpro:IPR025725|interpro:IPR025726|interpro:IPR038270|rcsb pdb:2QYU|rcsb pdb:2QZA|rcsb pdb:3SY2|rcsb pdb:5JW7|rcsb pdb:8ST8"	ensembl:ENSG00000185651.16(gene)|ensembl:ENST00000342192.9(transcript)|intact:EBI-711173(isoform-parent)	"psi-mi:""MI:0465""(dip)"	crc64:1D56B53EC05EDB94	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2024/11/14	rogid:HVE7zb36Q3b9GAfYxyunpbGI89M99287	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:754C7DF23FF92413|rigid:v6dLoH1uDujqkdpjdVEpSjJ5dH4	false	sufficient binding region:370-782	mutation decreasing interaction:63-63|fluorescent dye label:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8ZNR3	uniprotkb:P68036-1	intact:EBI-15674008	intact:EBI-15556257|ensembl:ENSP00000344259.5	psi-mi:sopa_salty(display_long)|uniprotkb:sopA(gene name)|psi-mi:sopA(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase SopA(gene name synonym)|uniprotkb:Salmonella outer protein A(gene name synonym)|uniprotkb:Secreted effector protein SopA(gene name synonym)|uniprotkb:STM2066(locus name)	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Diao et al. (2008)	pubmed:18066077|doi:10.1038/nsmb1346|imex:IM-9647	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15674077|imex:IM-9647-3|dip:DIP-88386E	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_461011.1|dip:DIP-46397N|refseq:WP_000703998.1|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043657""(host cell)|interpro:IPR025725|interpro:IPR025726|interpro:IPR038270|rcsb pdb:2QYU|rcsb pdb:2QZA|rcsb pdb:3SY2|rcsb pdb:5JW7|rcsb pdb:8ST8"	ensembl:ENSG00000185651.16(gene)|ensembl:ENST00000342192.9(transcript)|intact:EBI-711173(isoform-parent)	"psi-mi:""MI:0465""(dip)"	crc64:1D56B53EC05EDB94	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2024/11/14	rogid:HVE7zb36Q3b9GAfYxyunpbGI89M99287	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:DF923D77894ED74A|rigid:v6dLoH1uDujqkdpjdVEpSjJ5dH4	false	glutathione s tranferase tag:n-n|sufficient binding region:370-782	mutation decreasing interaction:63-63	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P0A2M9	uniprotkb:P28482	intact:EBI-15676035|uniprotkb:P21456	intact:EBI-959949|uniprotkb:A8CZ64|ensembl:ENSP00000215832.7|ensembl:ENSP00000381803.3	psi-mi:spvc_salty(display_long)|uniprotkb:spvC(gene name)|psi-mi:spvC(display_short)|uniprotkb:27.5 kDa virulence protein(gene name synonym)|uniprotkb:Secreted effector protein SpvC(gene name synonym)|uniprotkb:mkaD(gene name synonym)|uniprotkb:vsdD(gene name synonym)|uniprotkb:PSLT038(locus name)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	"psi-mi:""MI:0434""(phosphatase assay)"	Chen et al. (2008)	pubmed:18084305|doi:10.1038/nsmb1329|imex:IM-9651	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0203""(dephosphorylation reaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15676081|imex:IM-9651-1|dip:DIP-88393E	intact-miscore:0.68	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P0A2M9|refseq:NP_490528.1|refseq:WP_001122242.1|dip:DIP-46403N|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|interpro:IPR038498|rcsb pdb:2P1W|rcsb pdb:2Q8Y|rcsb pdb:2Z8M|rcsb pdb:2Z8N|rcsb pdb:2Z8O|rcsb pdb:2Z8P|rcsb pdb:4H43|rcsb pdb:4HAH"	"efo:""Orphanet:261330""|dip:DIP-519N|ensembl:ENSG00000100030.15(gene)|ensembl:ENST00000215832.11(transcript)|ensembl:ENST00000398822.7(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007611""(learning or memory)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0014044""(Schwann cell development)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019858""(cytosine metabolic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030641""(regulation of cellular pH)|go:""GO:0030878""(thyroid gland development)|go:""GO:0031143""(pseudopodium)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042473""(outer ear morphogenesis)|go:""GO:0042552""(myelination)|go:""GO:0042802""(identical protein binding)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0043401""(steroid hormone receptor signaling pathway)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060324""(face development)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0060440""(trachea formation)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0061308""(cardiac neural crest cell development involved in heart development)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070849""(response to epidermal growth factor)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:P28482|rcsb pdb:1PME|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|rcsb pdb:7AUV|rcsb pdb:7E73|rcsb pdb:7E75|rcsb pdb:7NQQ|rcsb pdb:7NQW|rcsb pdb:7NR3|rcsb pdb:7NR5|rcsb pdb:7NR8|rcsb pdb:7NR9|rcsb pdb:7OPM|rcsb pdb:7W5O|rcsb pdb:7X4U|rcsb pdb:7XC1|rcsb pdb:8AO2|rcsb pdb:8AO3|rcsb pdb:8AO4|rcsb pdb:8AO5|rcsb pdb:8AO6|rcsb pdb:8AO7|rcsb pdb:8AO8|rcsb pdb:8AO9|rcsb pdb:8AOA|rcsb pdb:8AOB|rcsb pdb:8AOC|rcsb pdb:8AOD|rcsb pdb:8AOE|rcsb pdb:8AOF|rcsb pdb:8AOG|rcsb pdb:8AOH|rcsb pdb:8AOI|rcsb pdb:8AOJ|rcsb pdb:8PSR|rcsb pdb:8PST|rcsb pdb:8PSW|rcsb pdb:8PSY|rcsb pdb:8PT0|rcsb pdb:8PT1|rcsb pdb:8PT3|rcsb pdb:8PT5|rcsb pdb:8U8J|rcsb pdb:8U8K|rcsb pdb:8ZJV|reactome:R-HSA-111995|reactome:R-HSA-112409|reactome:R-HSA-112411|reactome:R-HSA-1181150|reactome:R-HSA-1295596|reactome:R-HSA-1502540|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-877300|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-9725371|reactome:R-HSA-9732724|reactome:R-HSA-9768919|reactome:R-HSA-982772|reactome:R-HSA-9842640|reactome:R-HSA-9856649|refseq:NP_002736.3|refseq:NP_620407.1|panther:PTHR24055(orthology-group)"	"psi-mi:""MI:0465""(dip)"	crc64:77625271D78F8814	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2025/02/26	rogid:MezetuISvipnkk4GUAaruDCjolg99287	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	intact-crc:FC6E63039B50EC02|rigid:/5517FYB5Ed3ink/cC+MMNlrNnc	false	mutation disrupting interaction:100-100|mutation disrupting interaction:158-158|mutation disrupting interaction:86-86|mutation disrupting interaction:104-104|mutation disrupting interaction:106-106|mutation disrupting interaction:136-136|mutation disrupting interaction:148-148|mutation disrupting interaction:149-149|mutation disrupting interaction:213-213|mutation disrupting interaction:220-220|mutation disrupting interaction:220-220,148-148	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P08603	uniprotkb:Q9JXV4	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	intact:EBI-15758684	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	psi-mi:fhbp_neimb(display_long)|uniprotkb:fhbP(gene name)|psi-mi:fhbP(display_short)|uniprotkb:Genome-derived Neisseria antigen 1870(gene name synonym)|uniprotkb:Lipoprotein 2086(gene name synonym)|uniprotkb:NMB1870(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Schneider et al. (2009)	pubmed:19225461|doi:10.1038/nature07769|imex:IM-17830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:122586(strain mc58)|taxid:122586(Neisseria meningitidis serogroup B)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15758721|imex:IM-17830-2|dip:DIP-189249E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	"refseq:NP_274866.1|dip:DIP-59745N|go:""GO:0009279""(cell outer membrane)|go:""GO:0097691""(bacterial extracellular vesicle)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR014902(Lipoprotein GNA1870 C terminal like)|interpro:IPR049377|interpro:IPR049378|rcsb pdb:1YS5|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2Y7S|rcsb pdb:2YPV|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:5NQX|rcsb pdb:5NQZ|rcsb pdb:5O14|rcsb pdb:5T5F|rcsb pdb:6XZW|rcsb pdb:7KET|rcsb pdb:7LCV"	"psi-mi:""MI:0465""(dip)"	-	crc64:8CA166BCAC1B005C	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2025/01/22	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	rogid:P+OaUntPZhZb8JFoyV2GxTH3jI4122586	intact-crc:09ADF4005124FE1E|rigid:Qni1ejjvibuCkDdmWRpaH4yWHQg	false	binding-associated region:321-506	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08603	uniprotkb:Q9JXV4	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	intact:EBI-15758684	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	psi-mi:fhbp_neimb(display_long)|uniprotkb:fhbP(gene name)|psi-mi:fhbP(display_short)|uniprotkb:Genome-derived Neisseria antigen 1870(gene name synonym)|uniprotkb:Lipoprotein 2086(gene name synonym)|uniprotkb:NMB1870(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Schneider et al. (2009)	pubmed:19225461|doi:10.1038/nature07769|imex:IM-17830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:122586(strain mc58)|taxid:122586(Neisseria meningitidis serogroup B)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15758778|imex:IM-17830-5|dip:DIP-189249E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	"refseq:NP_274866.1|dip:DIP-59745N|go:""GO:0009279""(cell outer membrane)|go:""GO:0097691""(bacterial extracellular vesicle)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR014902(Lipoprotein GNA1870 C terminal like)|interpro:IPR049377|interpro:IPR049378|rcsb pdb:1YS5|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2Y7S|rcsb pdb:2YPV|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:5NQX|rcsb pdb:5NQZ|rcsb pdb:5O14|rcsb pdb:5T5F|rcsb pdb:6XZW|rcsb pdb:7KET|rcsb pdb:7LCV"	"psi-mi:""MI:0465""(dip)"	-	crc64:8CA166BCAC1B005C	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2025/01/22	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	rogid:P+OaUntPZhZb8JFoyV2GxTH3jI4122586	intact-crc:561D1B223B339A76|rigid:Qni1ejjvibuCkDdmWRpaH4yWHQg	false	sufficient binding region:321-443|mutation disrupting interaction:341-341,337-337	mutation disrupting interaction:258-258,237-237	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08603	uniprotkb:Q9JXV4	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	intact:EBI-15758684	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	psi-mi:fhbp_neimb(display_long)|uniprotkb:fhbP(gene name)|psi-mi:fhbP(display_short)|uniprotkb:Genome-derived Neisseria antigen 1870(gene name synonym)|uniprotkb:Lipoprotein 2086(gene name synonym)|uniprotkb:NMB1870(locus name)	"psi-mi:""MI:0114""(x-ray crystallography)"	Schneider et al. (2009)	pubmed:19225461|doi:10.1038/nature07769|imex:IM-17830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:122586(strain mc58)|taxid:122586(Neisseria meningitidis serogroup B)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15758742|imex:IM-17830-3|dip:DIP-189249E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	"refseq:NP_274866.1|dip:DIP-59745N|go:""GO:0009279""(cell outer membrane)|go:""GO:0097691""(bacterial extracellular vesicle)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR014902(Lipoprotein GNA1870 C terminal like)|interpro:IPR049377|interpro:IPR049378|rcsb pdb:1YS5|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2Y7S|rcsb pdb:2YPV|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:5NQX|rcsb pdb:5NQZ|rcsb pdb:5O14|rcsb pdb:5T5F|rcsb pdb:6XZW|rcsb pdb:7KET|rcsb pdb:7LCV"	"psi-mi:""MI:0465""(dip)"	-	crc64:8CA166BCAC1B005C	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2025/01/22	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	rogid:P+OaUntPZhZb8JFoyV2GxTH3jI4122586	intact-crc:EE03D0E1055EF5D6|rigid:Qni1ejjvibuCkDdmWRpaH4yWHQg	false	binding-associated region:321-443	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08603	uniprotkb:Q9JXV4	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	intact:EBI-15758684	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	psi-mi:fhbp_neimb(display_long)|uniprotkb:fhbP(gene name)|psi-mi:fhbP(display_short)|uniprotkb:Genome-derived Neisseria antigen 1870(gene name synonym)|uniprotkb:Lipoprotein 2086(gene name synonym)|uniprotkb:NMB1870(locus name)	"psi-mi:""MI:0047""(far western blotting)"	Schneider et al. (2009)	pubmed:19225461|doi:10.1038/nature07769|imex:IM-17830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:122586(strain mc58)|taxid:122586(Neisseria meningitidis serogroup B)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15758761|imex:IM-17830-4|dip:DIP-189249E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	"refseq:NP_274866.1|dip:DIP-59745N|go:""GO:0009279""(cell outer membrane)|go:""GO:0097691""(bacterial extracellular vesicle)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR014902(Lipoprotein GNA1870 C terminal like)|interpro:IPR049377|interpro:IPR049378|rcsb pdb:1YS5|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2Y7S|rcsb pdb:2YPV|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:5NQX|rcsb pdb:5NQZ|rcsb pdb:5O14|rcsb pdb:5T5F|rcsb pdb:6XZW|rcsb pdb:7KET|rcsb pdb:7LCV"	"psi-mi:""MI:0465""(dip)"	-	crc64:8CA166BCAC1B005C	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2025/01/22	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	rogid:P+OaUntPZhZb8JFoyV2GxTH3jI4122586	intact-crc:404D7E95E2ED1083|rigid:Qni1ejjvibuCkDdmWRpaH4yWHQg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08603	uniprotkb:Q9JXV4	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	intact:EBI-15758684	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	psi-mi:fhbp_neimb(display_long)|uniprotkb:fhbP(gene name)|psi-mi:fhbP(display_short)|uniprotkb:Genome-derived Neisseria antigen 1870(gene name synonym)|uniprotkb:Lipoprotein 2086(gene name synonym)|uniprotkb:NMB1870(locus name)	"psi-mi:""MI:0071""(molecular sieving)"	Schneider et al. (2009)	pubmed:19225461|doi:10.1038/nature07769|imex:IM-17830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:122586(strain mc58)|taxid:122586(Neisseria meningitidis serogroup B)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15758702|imex:IM-17830-1|dip:DIP-189249E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	"refseq:NP_274866.1|dip:DIP-59745N|go:""GO:0009279""(cell outer membrane)|go:""GO:0097691""(bacterial extracellular vesicle)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR014902(Lipoprotein GNA1870 C terminal like)|interpro:IPR049377|interpro:IPR049378|rcsb pdb:1YS5|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2Y7S|rcsb pdb:2YPV|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:5NQX|rcsb pdb:5NQZ|rcsb pdb:5O14|rcsb pdb:5T5F|rcsb pdb:6XZW|rcsb pdb:7KET|rcsb pdb:7LCV"	"psi-mi:""MI:0465""(dip)"	-	crc64:8CA166BCAC1B005C	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2025/01/22	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	rogid:P+OaUntPZhZb8JFoyV2GxTH3jI4122586	intact-crc:D9FBCA0AB2AEC642|rigid:Qni1ejjvibuCkDdmWRpaH4yWHQg	false	binding-associated region:321-443	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08603	uniprotkb:Q9JXV4	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	intact:EBI-15758684	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	psi-mi:fhbp_neimb(display_long)|uniprotkb:fhbP(gene name)|psi-mi:fhbP(display_short)|uniprotkb:Genome-derived Neisseria antigen 1870(gene name synonym)|uniprotkb:Lipoprotein 2086(gene name synonym)|uniprotkb:NMB1870(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Schneider et al. (2009)	pubmed:19225461|doi:10.1038/nature07769|imex:IM-17830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:122586(strain mc58)|taxid:122586(Neisseria meningitidis serogroup B)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15758805|imex:IM-17830-6|dip:DIP-189249E	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	"refseq:NP_274866.1|dip:DIP-59745N|go:""GO:0009279""(cell outer membrane)|go:""GO:0097691""(bacterial extracellular vesicle)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR014902(Lipoprotein GNA1870 C terminal like)|interpro:IPR049377|interpro:IPR049378|rcsb pdb:1YS5|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2Y7S|rcsb pdb:2YPV|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:5NQX|rcsb pdb:5NQZ|rcsb pdb:5O14|rcsb pdb:5T5F|rcsb pdb:6XZW|rcsb pdb:7KET|rcsb pdb:7LCV"	"psi-mi:""MI:0465""(dip)"	-	crc64:8CA166BCAC1B005C	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2025/01/22	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	rogid:P+OaUntPZhZb8JFoyV2GxTH3jI4122586	intact-crc:1DB82E69BDE3689B|rigid:Qni1ejjvibuCkDdmWRpaH4yWHQg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NNX6	uniprotkb:P35829	intact:EBI-9257341|uniprotkb:A8KAM4|uniprotkb:A8MVQ9|uniprotkb:G5E9C4|uniprotkb:Q2TB19|uniprotkb:Q96QP7|uniprotkb:Q96QP8|uniprotkb:Q96QP9|uniprotkb:Q96QQ0|uniprotkb:Q96QQ1|uniprotkb:Q96QQ2|uniprotkb:Q96QQ3|uniprotkb:Q96QQ4|uniprotkb:Q96QQ5|uniprotkb:Q96QQ6|uniprotkb:Q96QQ7|uniprotkb:Q96QQ8|ensembl:ENSP00000315477.6	intact:EBI-15743870|uniprotkb:Q5FMK4	psi-mi:cd209_human(display_long)|uniprotkb:CD209(gene name)|psi-mi:CD209(display_short)|uniprotkb:CLEC4L(gene name synonym)|uniprotkb:C-type lectin domain family 4 member L(gene name synonym)|uniprotkb:Dendritic cell-specific ICAM-3-grabbing non-integrin 1(gene name synonym)	psi-mi:slap_lacac(display_long)|uniprotkb:slpA(gene name)|psi-mi:slpA(display_short)|uniprotkb:Surface layer protein(gene name synonym)|uniprotkb:LBA0169(locus name)	"psi-mi:""MI:0892""(solid phase assay)"	Konstantinov et al. (2008)	pubmed:19047644|doi:10.1073/pnas.0810305105|imex:IM-22479	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:272621(lacac)|taxid:272621(""Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15743887|imex:IM-22479-1|dip:DIP-196244E	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066978.1|refseq:NP_001138365.1|refseq:NP_001138366.1|refseq:NP_001138367.1|refseq:NP_001138368.1|refseq:NP_001138369.1|dip:DIP-60629N|ensembl:ENSG00000090659.18(gene)|ensembl:ENST00000315599.12(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0006955""(immune response)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0009988""(cell-cell recognition)|go:""GO:0016020""(membrane)|go:""GO:0019062""(virion attachment to host cell)|go:""GO:0019079""(viral genome replication)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0043657""(host cell)|go:""GO:0045087""(innate immune response)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046790""(virion binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0046968""(peptide antigen transport)|go:""GO:0075733""(intracellular transport of virus)|go:""GO:0097323""(B cell adhesion)|go:""GO:1903902""(positive regulation of viral life cycle)|rcsb pdb:7NL6|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|interpro:IPR050111|rcsb pdb:1K9I|rcsb pdb:1SL4|rcsb pdb:1SL5|rcsb pdb:2B6B|rcsb pdb:2IT5|rcsb pdb:2IT6|rcsb pdb:2XR5|rcsb pdb:2XR6|rcsb pdb:6GHV|rcsb pdb:7NL7|reactome:R-HSA-5621575|reactome:R-HSA-8851680|reactome:R-HSA-9833110|panther:PTHR22802(orthology-group)"	"refseq:WP_011254065.1|refseq:YP_193101.1|dip:DIP-60786N|go:""GO:0005199""(structural constituent of cell wall)|go:""GO:0005576""(extracellular region)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0030115""(S-layer)|interpro:IPR004903(Bacterial surface layer protein)|interpro:IPR024968|interpro:IPR055005|interpro:IPR055006|rcsb pdb:7QFG|rcsb pdb:7QFL|rcsb pdb:7QLD|rcsb pdb:7QLE|rcsb pdb:8ALU|rcsb pdb:8BT9"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2024/11/14	rogid:veaQUZyFcAP3yYQgh9zN9sEzvUI9606	rogid:2bvJv5zQiw1ttXohkfRhUUALC74272621	intact-crc:8204A76CF4217930|rigid:exMxuIifeckoJSHm5IncDSFq3DE	false	fc-igg tag:c-c	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P15917	uniprotkb:P53618	intact:EBI-456923|uniprotkb:Q8KYJ6|uniprotkb:Q933F6	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923.3|ensembl:ENSP00000397873.2	psi-mi:lef_bacan(display_long)|uniprotkb:Anthrax lethal toxin endopeptidase component(gene name synonym)|uniprotkb:lef(gene name)|psi-mi:lef(display_short)|uniprotkb:pXO1-107(locus name)|uniprotkb:BXA0172(locus name)|uniprotkb:GBAA_pXO1_0172(locus name)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Tamayo et al. (2008)	pubmed:18356299|doi:10.1073/pnas.0710100105|imex:IM-9201	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15694156|imex:IM-9201-1|dip:DIP-59368E	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_052803.1|refseq:WP_001022097.1|refseq:WP_010890024.1|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0044164""(host cell cytosol)|go:""GO:0090729""(toxin activity)|interpro:IPR003541(Anthrax toxin, lethal/endema factor, N-terminal)|interpro:IPR014781(Anthrax toxin, lethal/endema factor, N- and C-terminal)|interpro:IPR015239(Anthrax toxin, lethal factor, central)|interpro:IPR024079|interpro:IPR047568|rcsb pdb:1J7N|rcsb pdb:1JKY|rcsb pdb:1PWP|rcsb pdb:1PWQ|rcsb pdb:1PWU|rcsb pdb:1PWV|rcsb pdb:1PWW|rcsb pdb:1YQY|rcsb pdb:1ZXV|rcsb pdb:2L0R|rcsb pdb:3KWV|rcsb pdb:4DV8|rcsb pdb:4PKQ|rcsb pdb:4PKR|rcsb pdb:4PKS|rcsb pdb:4PKT|rcsb pdb:4PKU|rcsb pdb:4PKV|rcsb pdb:4PKW|rcsb pdb:4WF6|rcsb pdb:4XM6|rcsb pdb:4XM7|rcsb pdb:4XM8|rcsb pdb:5D1S|rcsb pdb:5D1T|rcsb pdb:5D1U|rcsb pdb:6PSN|rcsb pdb:6WJJ|rcsb pdb:6ZXJ|rcsb pdb:6ZXK|rcsb pdb:6ZXL|rcsb pdb:7KXR|reactome:R-HSA-5210891|dip:DIP-29871N|mint:P15917"	"panther:PTHR10635(orthology-group)|efo:""Orphanet:633035""|ensembl:ENSG00000129083.13(gene)|ensembl:ENST00000249923.7(transcript)|ensembl:ENST00000439561.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0016020""(membrane)|go:""GO:0030126""(COPI vesicle coat)|go:""GO:0030133""(transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|dip:DIP-265N"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2025/03/01	rogid:HvuMhoQb9eCHIox5O6RIVFknPMc1392	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	intact-crc:EC6CAA018A31CEA1|rigid:MAnAJZbypTe6dtTmnMgfDqncBfc	false	binding-associated region:1-254|tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P15917	uniprotkb:P61923	intact:EBI-456923|uniprotkb:Q8KYJ6|uniprotkb:Q933F6	intact:EBI-1049939|uniprotkb:Q549N6|uniprotkb:Q9Y3C3|uniprotkb:B4DDX8|uniprotkb:F8VS17|uniprotkb:F8VWL5|uniprotkb:B4DHZ0|ensembl:ENSP00000262061.2	psi-mi:lef_bacan(display_long)|uniprotkb:Anthrax lethal toxin endopeptidase component(gene name synonym)|uniprotkb:lef(gene name)|psi-mi:lef(display_short)|uniprotkb:pXO1-107(locus name)|uniprotkb:BXA0172(locus name)|uniprotkb:GBAA_pXO1_0172(locus name)	psi-mi:copz1_human(display_long)|uniprotkb:Zeta-1-coat protein(gene name synonym)|uniprotkb:COPZ1(gene name)|psi-mi:COPZ1(display_short)|uniprotkb:COPZ(gene name synonym)|uniprotkb:CGI-120(orf name)|uniprotkb:HSPC181(orf name)	"psi-mi:""MI:0096""(pull down)"	Tamayo et al. (2008)	pubmed:18356299|doi:10.1073/pnas.0710100105|imex:IM-9201	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-15694195|imex:IM-9201-2|dip:DIP-59369E	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_052803.1|refseq:WP_001022097.1|refseq:WP_010890024.1|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0044164""(host cell cytosol)|go:""GO:0090729""(toxin activity)|interpro:IPR003541(Anthrax toxin, lethal/endema factor, N-terminal)|interpro:IPR014781(Anthrax toxin, lethal/endema factor, N- and C-terminal)|interpro:IPR015239(Anthrax toxin, lethal factor, central)|interpro:IPR024079|interpro:IPR047568|rcsb pdb:1J7N|rcsb pdb:1JKY|rcsb pdb:1PWP|rcsb pdb:1PWQ|rcsb pdb:1PWU|rcsb pdb:1PWV|rcsb pdb:1PWW|rcsb pdb:1YQY|rcsb pdb:1ZXV|rcsb pdb:2L0R|rcsb pdb:3KWV|rcsb pdb:4DV8|rcsb pdb:4PKQ|rcsb pdb:4PKR|rcsb pdb:4PKS|rcsb pdb:4PKT|rcsb pdb:4PKU|rcsb pdb:4PKV|rcsb pdb:4PKW|rcsb pdb:4WF6|rcsb pdb:4XM6|rcsb pdb:4XM7|rcsb pdb:4XM8|rcsb pdb:5D1S|rcsb pdb:5D1T|rcsb pdb:5D1U|rcsb pdb:6PSN|rcsb pdb:6WJJ|rcsb pdb:6ZXJ|rcsb pdb:6ZXK|rcsb pdb:6ZXL|rcsb pdb:7KXR|reactome:R-HSA-5210891|dip:DIP-29871N|mint:P15917"	"refseq:NP_057141.1|refseq:NP_001258663.1|refseq:NP_001258664.1|refseq:NP_001258665.1|ensembl:ENSG00000111481.10(gene)|ensembl:ENST00000262061.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0030126""(COPI vesicle coat)|go:""GO:0030133""(transport vesicle)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR039652|rcsb pdb:2HF6|rcsb pdb:5MC7|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29873N|panther:PTHR11043(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2025/02/28	rogid:HvuMhoQb9eCHIox5O6RIVFknPMc1392	rogid:1/IgMqSz7ThLUzNhR4ARUq+Gr6I9606	intact-crc:36C29FE29543AAA7|rigid:ZSx4D+IdHM/mlzMB6l6xWoJDgWI	false	binding-associated region:1-254|tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q9Y4G2	uniprotkb:A0A0D6GID3	intact:EBI-473814|uniprotkb:Q6P2R5|uniprotkb:Q8TEL9|uniprotkb:Q9NPP5|intact:EBI-715406|uniprotkb:Q9NYA0|ensembl:ENSP00000389913.3|ensembl:ENSP00000394344.3|ensembl:ENSP00000479066.1|ensembl:ENSP00000483820.1	intact:EBI-30861778|uniprotkb:A0A0F7J5X6|uniprotkb:A0A0H3TAV8	psi-mi:pkhm1_human(display_long)|uniprotkb:PLEKHM1(gene name)|psi-mi:PLEKHM1(display_short)|uniprotkb:KIAA0356(gene name synonym)|uniprotkb:162 kDa adapter protein(gene name synonym)	psi-mi:a0a0d6gid3_saltm(display_long)|uniprotkb:F3R12_12495(orf name)|uniprotkb:GB466_09595(orf name)|uniprotkb:SE14_01284(orf name)|uniprotkb:AAB27_11880(orf name)|uniprotkb:AU613_01250(orf name)|uniprotkb:AVC05_23275(orf name)|uniprotkb:B1P38_20705(orf name)|uniprotkb:CE70_03980(orf name)|uniprotkb:CFF59_11850(orf name)|uniprotkb:DU071_12050(orf name)|uniprotkb:D6J79_13420(orf name)|uniprotkb:DD95_24440(orf name)|uniprotkb:DMO92_18435(orf name)|uniprotkb:DPF41_17540(orf name)|uniprotkb:DPS76_10435(orf name)|uniprotkb:DRM14_06165(orf name)|uniprotkb:E0935_07325(orf name)|uniprotkb:EER35_18295(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	"psi-mi:""MI:0096""(pull down)"	McEwan et al. (2015)	pubmed:25500191|imex:IM-29458	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:90371(saltm)|taxid:90371(Salmonella typhimurium)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-30873510|imex:IM-29458-36	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000225190.12(gene)|ensembl:ENSG00000276358.2(gene)|ensembl:ENSG00000277111.3(gene)|ensembl:ENST00000430334.8(transcript)|ensembl:ENST00000446609.7(transcript)|ensembl:ENST00000613787.3(transcript)|ensembl:ENST00000617688.2(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005764""(lysosome)|go:""GO:0015031""(protein transport)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032418""(lysosome localization)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044754""(autolysosome)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:0120281""(autolysosome membrane)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1902774""(late endosome to lysosome transport)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025258|interpro:IPR037213|interpro:IPR042827|interpro:IPR047326|interpro:IPR051366|mint:Q9Y4G2|rcsb pdb:5DPR|rcsb pdb:5DPS|rcsb pdb:5DPT|rcsb pdb:5DPW|rcsb pdb:8JC5|refseq:NP_055613.1|refseq:XP_006722264.1|refseq:XP_011523825.1|refseq:XP_011523826.1|refseq:XP_016880940.1|refseq:XP_016880942.1|panther:PTHR12326(orthology-group)|efo:""Orphanet:210110"""	interpro:IPR044928|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	-	-	figure legend:5b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2022/02/23	2024/11/14	rogid:g3g9CyLRMoFDvX6Yoc231I8+y5E9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk90371	intact-crc:626949179C0D5305|rigid:U6SlkCwDMhd0Lqu0AeGHbs1pSv0	false	maltose binding protein tag:n-n	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0D6GID3	uniprotkb:Q9Y4G2	intact:EBI-30861778|uniprotkb:A0A0F7J5X6|uniprotkb:A0A0H3TAV8	intact:EBI-473814|uniprotkb:Q6P2R5|uniprotkb:Q8TEL9|uniprotkb:Q9NPP5|intact:EBI-715406|uniprotkb:Q9NYA0|ensembl:ENSP00000389913.3|ensembl:ENSP00000394344.3|ensembl:ENSP00000479066.1|ensembl:ENSP00000483820.1	psi-mi:a0a0d6gid3_saltm(display_long)|uniprotkb:F3R12_12495(orf name)|uniprotkb:GB466_09595(orf name)|uniprotkb:SE14_01284(orf name)|uniprotkb:AAB27_11880(orf name)|uniprotkb:AU613_01250(orf name)|uniprotkb:AVC05_23275(orf name)|uniprotkb:B1P38_20705(orf name)|uniprotkb:CE70_03980(orf name)|uniprotkb:CFF59_11850(orf name)|uniprotkb:DU071_12050(orf name)|uniprotkb:D6J79_13420(orf name)|uniprotkb:DD95_24440(orf name)|uniprotkb:DMO92_18435(orf name)|uniprotkb:DPF41_17540(orf name)|uniprotkb:DPS76_10435(orf name)|uniprotkb:DRM14_06165(orf name)|uniprotkb:E0935_07325(orf name)|uniprotkb:EER35_18295(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	psi-mi:pkhm1_human(display_long)|uniprotkb:PLEKHM1(gene name)|psi-mi:PLEKHM1(display_short)|uniprotkb:KIAA0356(gene name synonym)|uniprotkb:162 kDa adapter protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	McEwan et al. (2015)	pubmed:25500191|imex:IM-29458	taxid:90371(saltm)|taxid:90371(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-30863254|imex:IM-29458-11	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000225190.12(gene)|ensembl:ENSG00000276358.2(gene)|ensembl:ENSG00000277111.3(gene)|ensembl:ENST00000430334.8(transcript)|ensembl:ENST00000446609.7(transcript)|ensembl:ENST00000613787.3(transcript)|ensembl:ENST00000617688.2(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005764""(lysosome)|go:""GO:0015031""(protein transport)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032418""(lysosome localization)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044754""(autolysosome)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:0120281""(autolysosome membrane)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1902774""(late endosome to lysosome transport)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025258|interpro:IPR037213|interpro:IPR042827|interpro:IPR047326|interpro:IPR051366|mint:Q9Y4G2|rcsb pdb:5DPR|rcsb pdb:5DPS|rcsb pdb:5DPT|rcsb pdb:5DPW|rcsb pdb:8JC5|refseq:NP_055613.1|refseq:XP_006722264.1|refseq:XP_011523825.1|refseq:XP_011523826.1|refseq:XP_016880940.1|refseq:XP_016880942.1|panther:PTHR12326(orthology-group)|efo:""Orphanet:210110"""	-	-	-	figure legend:5a, S5a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2022/02/23	2024/11/14	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk90371	rogid:g3g9CyLRMoFDvX6Yoc231I8+y5E9606	intact-crc:3CA3BD9F6382691E|rigid:U6SlkCwDMhd0Lqu0AeGHbs1pSv0	false	green fluorescent protein tag:?-?|sufficient binding region:1-140	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0D6GID3	uniprotkb:Q9Y4G2	intact:EBI-30861778|uniprotkb:A0A0F7J5X6|uniprotkb:A0A0H3TAV8	intact:EBI-473814|uniprotkb:Q6P2R5|uniprotkb:Q8TEL9|uniprotkb:Q9NPP5|intact:EBI-715406|uniprotkb:Q9NYA0|ensembl:ENSP00000389913.3|ensembl:ENSP00000394344.3|ensembl:ENSP00000479066.1|ensembl:ENSP00000483820.1	psi-mi:a0a0d6gid3_saltm(display_long)|uniprotkb:F3R12_12495(orf name)|uniprotkb:GB466_09595(orf name)|uniprotkb:SE14_01284(orf name)|uniprotkb:AAB27_11880(orf name)|uniprotkb:AU613_01250(orf name)|uniprotkb:AVC05_23275(orf name)|uniprotkb:B1P38_20705(orf name)|uniprotkb:CE70_03980(orf name)|uniprotkb:CFF59_11850(orf name)|uniprotkb:DU071_12050(orf name)|uniprotkb:D6J79_13420(orf name)|uniprotkb:DD95_24440(orf name)|uniprotkb:DMO92_18435(orf name)|uniprotkb:DPF41_17540(orf name)|uniprotkb:DPS76_10435(orf name)|uniprotkb:DRM14_06165(orf name)|uniprotkb:E0935_07325(orf name)|uniprotkb:EER35_18295(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	psi-mi:pkhm1_human(display_long)|uniprotkb:PLEKHM1(gene name)|psi-mi:PLEKHM1(display_short)|uniprotkb:KIAA0356(gene name synonym)|uniprotkb:162 kDa adapter protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	McEwan et al. (2015)	pubmed:25500191|imex:IM-29458	taxid:90371(saltm)|taxid:90371(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-30873372|imex:IM-29458-28	intact-miscore:0.59	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000225190.12(gene)|ensembl:ENSG00000276358.2(gene)|ensembl:ENSG00000277111.3(gene)|ensembl:ENST00000430334.8(transcript)|ensembl:ENST00000446609.7(transcript)|ensembl:ENST00000613787.3(transcript)|ensembl:ENST00000617688.2(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005764""(lysosome)|go:""GO:0015031""(protein transport)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032418""(lysosome localization)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044754""(autolysosome)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:0120281""(autolysosome membrane)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1902774""(late endosome to lysosome transport)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025258|interpro:IPR037213|interpro:IPR042827|interpro:IPR047326|interpro:IPR051366|mint:Q9Y4G2|rcsb pdb:5DPR|rcsb pdb:5DPS|rcsb pdb:5DPT|rcsb pdb:5DPW|rcsb pdb:8JC5|refseq:NP_055613.1|refseq:XP_006722264.1|refseq:XP_011523825.1|refseq:XP_011523826.1|refseq:XP_016880940.1|refseq:XP_016880942.1|panther:PTHR12326(orthology-group)|efo:""Orphanet:210110"""	-	-	-	figure legend:S5b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2022/02/23	2025/03/21	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk90371	rogid:g3g9CyLRMoFDvX6Yoc231I8+y5E9606	intact-crc:05239290C8F4E5EF|rigid:oAoWyfxNSbklT3SyfwlAGjuN0yM	false	green fluorescent protein tag:?-?|sufficient binding region:1-140	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0D6GID3	uniprotkb:Q13573	intact:EBI-30861778|uniprotkb:A0A0F7J5X6|uniprotkb:A0A0H3TAV8	intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531.8	psi-mi:a0a0d6gid3_saltm(display_long)|uniprotkb:F3R12_12495(orf name)|uniprotkb:GB466_09595(orf name)|uniprotkb:SE14_01284(orf name)|uniprotkb:AAB27_11880(orf name)|uniprotkb:AU613_01250(orf name)|uniprotkb:AVC05_23275(orf name)|uniprotkb:B1P38_20705(orf name)|uniprotkb:CE70_03980(orf name)|uniprotkb:CFF59_11850(orf name)|uniprotkb:DU071_12050(orf name)|uniprotkb:D6J79_13420(orf name)|uniprotkb:DD95_24440(orf name)|uniprotkb:DMO92_18435(orf name)|uniprotkb:DPF41_17540(orf name)|uniprotkb:DPS76_10435(orf name)|uniprotkb:DRM14_06165(orf name)|uniprotkb:E0935_07325(orf name)|uniprotkb:EER35_18295(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	McEwan et al. (2015)	pubmed:25500191|imex:IM-29458	taxid:90371(saltm)|taxid:90371(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-30873372|imex:IM-29458-28	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_036377.1|ensembl:ENSG00000100603.14(gene)|ensembl:ENST00000261531.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005112""(Notch binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016604""(nuclear body)|go:""GO:0016607""(nuclear speck)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0048385""(regulation of retinoic acid receptor signaling pathway)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0070562""(regulation of vitamin D receptor signaling pathway)|go:""GO:0070564""(positive regulation of vitamin D receptor signaling pathway)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071300""(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8RO2|rcsb pdb:9FMD|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|dip:DIP-34800N|panther:PTHR12096(orthology-group)"	-	-	-	figure legend:S5b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2022/02/23	2025/03/21	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk90371	rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606	intact-crc:05239290C8F4E5EF|rigid:oAoWyfxNSbklT3SyfwlAGjuN0yM	false	green fluorescent protein tag:?-?|sufficient binding region:1-140	ha tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9Y4G2	uniprotkb:A0A0D6GID3	intact:EBI-473814|uniprotkb:Q6P2R5|uniprotkb:Q8TEL9|uniprotkb:Q9NPP5|intact:EBI-715406|uniprotkb:Q9NYA0|ensembl:ENSP00000389913.3|ensembl:ENSP00000394344.3|ensembl:ENSP00000479066.1|ensembl:ENSP00000483820.1	intact:EBI-30861778|uniprotkb:A0A0F7J5X6|uniprotkb:A0A0H3TAV8	psi-mi:pkhm1_human(display_long)|uniprotkb:PLEKHM1(gene name)|psi-mi:PLEKHM1(display_short)|uniprotkb:KIAA0356(gene name synonym)|uniprotkb:162 kDa adapter protein(gene name synonym)	psi-mi:a0a0d6gid3_saltm(display_long)|uniprotkb:F3R12_12495(orf name)|uniprotkb:GB466_09595(orf name)|uniprotkb:SE14_01284(orf name)|uniprotkb:AAB27_11880(orf name)|uniprotkb:AU613_01250(orf name)|uniprotkb:AVC05_23275(orf name)|uniprotkb:B1P38_20705(orf name)|uniprotkb:CE70_03980(orf name)|uniprotkb:CFF59_11850(orf name)|uniprotkb:DU071_12050(orf name)|uniprotkb:D6J79_13420(orf name)|uniprotkb:DD95_24440(orf name)|uniprotkb:DMO92_18435(orf name)|uniprotkb:DPF41_17540(orf name)|uniprotkb:DPS76_10435(orf name)|uniprotkb:DRM14_06165(orf name)|uniprotkb:E0935_07325(orf name)|uniprotkb:EER35_18295(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	McEwan et al. (2015)	pubmed:25500191|imex:IM-29458	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:90371(saltm)|taxid:90371(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-30873386|imex:IM-29458-30	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000225190.12(gene)|ensembl:ENSG00000276358.2(gene)|ensembl:ENSG00000277111.3(gene)|ensembl:ENST00000430334.8(transcript)|ensembl:ENST00000446609.7(transcript)|ensembl:ENST00000613787.3(transcript)|ensembl:ENST00000617688.2(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005764""(lysosome)|go:""GO:0015031""(protein transport)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032418""(lysosome localization)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044754""(autolysosome)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:0120281""(autolysosome membrane)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1902774""(late endosome to lysosome transport)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025258|interpro:IPR037213|interpro:IPR042827|interpro:IPR047326|interpro:IPR051366|mint:Q9Y4G2|rcsb pdb:5DPR|rcsb pdb:5DPS|rcsb pdb:5DPT|rcsb pdb:5DPW|rcsb pdb:8JC5|refseq:NP_055613.1|refseq:XP_006722264.1|refseq:XP_011523825.1|refseq:XP_011523826.1|refseq:XP_016880940.1|refseq:XP_016880942.1|panther:PTHR12326(orthology-group)|efo:""Orphanet:210110"""	interpro:IPR044928|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	caution:We have Serine at 744; and Lysine at 747 - so the mutation position has been changed accordingly	-	figure legend:S5d, 5c, 5d|caution:Lysine is at 747, not at 744 - the mutation numbering has been updated accordingly|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2022/02/23	2024/11/14	rogid:g3g9CyLRMoFDvX6Yoc231I8+y5E9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk90371	intact-crc:0D0E1D61416B6B95|rigid:U6SlkCwDMhd0Lqu0AeGHbs1pSv0	false	flag tag:?-?|mutation with no effect:732-732|mutation with no effect:733-733,735-735|mutation with no effect:734-734|mutation with no effect:736-736|mutation with no effect:737-737|mutation with no effect:740-740|mutation disrupting interaction strength:769-769|mutation with no effect:773-773|mutation with no effect:747-747|necessary binding region:670-788|mutation disrupting interaction strength:729-729|mutation decreasing interaction strength:730-730|mutation increasing interaction strength:731-731	myc tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0D6GID3	uniprotkb:Q13573	intact:EBI-30861778|uniprotkb:A0A0F7J5X6|uniprotkb:A0A0H3TAV8	intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531.8	psi-mi:a0a0d6gid3_saltm(display_long)|uniprotkb:F3R12_12495(orf name)|uniprotkb:GB466_09595(orf name)|uniprotkb:SE14_01284(orf name)|uniprotkb:AAB27_11880(orf name)|uniprotkb:AU613_01250(orf name)|uniprotkb:AVC05_23275(orf name)|uniprotkb:B1P38_20705(orf name)|uniprotkb:CE70_03980(orf name)|uniprotkb:CFF59_11850(orf name)|uniprotkb:DU071_12050(orf name)|uniprotkb:D6J79_13420(orf name)|uniprotkb:DD95_24440(orf name)|uniprotkb:DMO92_18435(orf name)|uniprotkb:DPF41_17540(orf name)|uniprotkb:DPS76_10435(orf name)|uniprotkb:DRM14_06165(orf name)|uniprotkb:E0935_07325(orf name)|uniprotkb:EER35_18295(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	McEwan et al. (2015)	pubmed:25500191|imex:IM-29458	taxid:90371(saltm)|taxid:90371(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-30873492|imex:IM-29458-34	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_036377.1|ensembl:ENSG00000100603.14(gene)|ensembl:ENST00000261531.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005112""(Notch binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016604""(nuclear body)|go:""GO:0016607""(nuclear speck)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0048385""(regulation of retinoic acid receptor signaling pathway)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0070562""(regulation of vitamin D receptor signaling pathway)|go:""GO:0070564""(positive regulation of vitamin D receptor signaling pathway)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071300""(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8RO2|rcsb pdb:9FMD|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|dip:DIP-34800N|panther:PTHR12096(orthology-group)"	-	-	-	figure legend:5a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2022/02/23	2025/03/21	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk90371	rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606	intact-crc:24C7C64241500CB0|rigid:DX133mPehVmD7ioOztUqFwHJlXo	false	green fluorescent protein tag:?-?	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0D6GID3	uniprotkb:P51149	intact:EBI-30861778|uniprotkb:A0A0F7J5X6|uniprotkb:A0A0H3TAV8	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062.3|ensembl:ENSP00000501618.1|ensembl:ENSP00000502000.1|ensembl:ENSP00000502088.1|ensembl:ENSP00000502486.1	psi-mi:a0a0d6gid3_saltm(display_long)|uniprotkb:F3R12_12495(orf name)|uniprotkb:GB466_09595(orf name)|uniprotkb:SE14_01284(orf name)|uniprotkb:AAB27_11880(orf name)|uniprotkb:AU613_01250(orf name)|uniprotkb:AVC05_23275(orf name)|uniprotkb:B1P38_20705(orf name)|uniprotkb:CE70_03980(orf name)|uniprotkb:CFF59_11850(orf name)|uniprotkb:DU071_12050(orf name)|uniprotkb:D6J79_13420(orf name)|uniprotkb:DD95_24440(orf name)|uniprotkb:DMO92_18435(orf name)|uniprotkb:DPF41_17540(orf name)|uniprotkb:DPS76_10435(orf name)|uniprotkb:DRM14_06165(orf name)|uniprotkb:E0935_07325(orf name)|uniprotkb:EER35_18295(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	McEwan et al. (2015)	pubmed:25500191|imex:IM-29458	taxid:90371(saltm)|taxid:90371(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-30862695|imex:IM-29458-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000075785.14(gene)|ensembl:ENST00000265062.8(transcript)|ensembl:ENST00000674589.1(transcript)|ensembl:ENST00000675342.1(transcript)|ensembl:ENST00000675497.1(transcript)|ensembl:ENST00000676214.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0019003""(GDP binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0036466""(synaptic vesicle recycling via endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045453""(bone resorption)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048524""(positive regulation of viral process)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090383""(phagosome acidification)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0097208""(alveolar lamellar body)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:1903542""(negative regulation of exosomal secretion)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1905366""(negative regulation of intralumenal vesicle formation)|go:""GO:1905394""(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:3LAW|rcsb pdb:6IYB|rcsb pdb:6WCW|rcsb pdb:7F6J|rcsb pdb:8KB8|rcsb pdb:8ZQ3|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|refseq:NP_004628.4|efo:""Orphanet:99936""|dip:DIP-39879N|panther:PTHR47981(orthology-group)"	-	-	-	figure legend:4c|comment:Cells were infected with Salmonella|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela-T-Rex)|taxid:9606(Homo sapiens HeLa-T-Rex epitheloid cervical carcinoma cell)	-	2022/02/23	2025/03/10	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk90371	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	intact-crc:F2B61CB5C52624D9|rigid:YJum0PAVEMQywQuTKU7GoAzeWNE	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0D6GID3	uniprotkb:Q9Y4G2	intact:EBI-30861778|uniprotkb:A0A0F7J5X6|uniprotkb:A0A0H3TAV8	intact:EBI-473814|uniprotkb:Q6P2R5|uniprotkb:Q8TEL9|uniprotkb:Q9NPP5|intact:EBI-715406|uniprotkb:Q9NYA0|ensembl:ENSP00000389913.3|ensembl:ENSP00000394344.3|ensembl:ENSP00000479066.1|ensembl:ENSP00000483820.1	psi-mi:a0a0d6gid3_saltm(display_long)|uniprotkb:F3R12_12495(orf name)|uniprotkb:GB466_09595(orf name)|uniprotkb:SE14_01284(orf name)|uniprotkb:AAB27_11880(orf name)|uniprotkb:AU613_01250(orf name)|uniprotkb:AVC05_23275(orf name)|uniprotkb:B1P38_20705(orf name)|uniprotkb:CE70_03980(orf name)|uniprotkb:CFF59_11850(orf name)|uniprotkb:DU071_12050(orf name)|uniprotkb:D6J79_13420(orf name)|uniprotkb:DD95_24440(orf name)|uniprotkb:DMO92_18435(orf name)|uniprotkb:DPF41_17540(orf name)|uniprotkb:DPS76_10435(orf name)|uniprotkb:DRM14_06165(orf name)|uniprotkb:E0935_07325(orf name)|uniprotkb:EER35_18295(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	psi-mi:pkhm1_human(display_long)|uniprotkb:PLEKHM1(gene name)|psi-mi:PLEKHM1(display_short)|uniprotkb:KIAA0356(gene name synonym)|uniprotkb:162 kDa adapter protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	McEwan et al. (2015)	pubmed:25500191|imex:IM-29458	taxid:90371(saltm)|taxid:90371(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-30862695|imex:IM-29458-7	intact-miscore:0.59	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000225190.12(gene)|ensembl:ENSG00000276358.2(gene)|ensembl:ENSG00000277111.3(gene)|ensembl:ENST00000430334.8(transcript)|ensembl:ENST00000446609.7(transcript)|ensembl:ENST00000613787.3(transcript)|ensembl:ENST00000617688.2(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005764""(lysosome)|go:""GO:0015031""(protein transport)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032418""(lysosome localization)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044754""(autolysosome)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:0120281""(autolysosome membrane)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1902774""(late endosome to lysosome transport)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025258|interpro:IPR037213|interpro:IPR042827|interpro:IPR047326|interpro:IPR051366|mint:Q9Y4G2|rcsb pdb:5DPR|rcsb pdb:5DPS|rcsb pdb:5DPT|rcsb pdb:5DPW|rcsb pdb:8JC5|refseq:NP_055613.1|refseq:XP_006722264.1|refseq:XP_011523825.1|refseq:XP_011523826.1|refseq:XP_016880940.1|refseq:XP_016880942.1|panther:PTHR12326(orthology-group)|efo:""Orphanet:210110"""	-	-	-	figure legend:4c|comment:Cells were infected with Salmonella|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela-T-Rex)|taxid:9606(Homo sapiens HeLa-T-Rex epitheloid cervical carcinoma cell)	-	2022/02/23	2025/03/10	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk90371	rogid:g3g9CyLRMoFDvX6Yoc231I8+y5E9606	intact-crc:F2B61CB5C52624D9|rigid:YJum0PAVEMQywQuTKU7GoAzeWNE	false	ha tag:?-?	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0F6B063	uniprotkb:Q7Z2W4	intact:EBI-11477981	intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351.5	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_064504.2|refseq:NP_078901.3|dip:DIP-37896N|ensembl:ENSG00000105939.14(gene)|ensembl:ENST00000242351.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0009615""(response to virus)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0061014""(positive regulation of mRNA catabolic process)|go:""GO:1900246""(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|interpro:IPR051712|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|rcsb pdb:7KZH|rcsb pdb:7TGQ|reactome:R-HSA-6802952|panther:PTHR45740(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q9UKV8	intact:EBI-11477981	intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592.5	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:5JS2|rcsb pdb:5KI6|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|rcsb pdb:7KI3|rcsb pdb:8D6J|rcsb pdb:8D71|rcsb pdb:8THQ|rcsb pdb:9BEZ|rcsb pdb:9BF0|rcsb pdb:9BF2|ensembl:ENSG00000123908.12(gene)|ensembl:ENST00000220592.10(transcript)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000932""(P-body)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010501""(obsolete RNA secondary structure unwinding)|go:""GO:0010586""(miRNA metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016442""(RISC complex)|go:""GO:0030422""(siRNA processing)|go:""GO:0030425""(dendrite)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031054""(pre-miRNA processing)|go:""GO:0033962""(P-body assembly)|go:""GO:0035194""(regulatory ncRNA-mediated post-transcriptional gene silencing)|go:""GO:0035196""(miRNA processing)|go:""GO:0035197""(siRNA binding)|go:""GO:0035198""(miRNA binding)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0035279""(miRNA-mediated gene silencing by mRNA destabilization)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042985""(negative regulation of amyloid precursor protein biosynthetic process)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0070551""(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:""GO:0070578""(RISC-loading complex)|go:""GO:0070922""(RISC complex assembly)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090624""(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:""GO:0090625""(siRNA-mediated gene silencing by mRNA destabilization)|go:""GO:0098794""(postsynapse)|go:""GO:0098808""(mRNA cap binding)|go:""GO:0098978""(glutamatergic synapse)|reactome:R-HSA-1912408|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901165""(positive regulation of trophoblast cell migration)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|interpro:IPR045246|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|rcsb pdb:3QX9|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9725371|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9820841|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001158095.1|refseq:NP_036286.2|dip:DIP-29194N|efo:""Orphanet:528084""|panther:PTHR22891(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q9BVP2	intact:EBI-11477981	intact:EBI-641642|uniprotkb:Q96SV6|uniprotkb:Q96SV7|uniprotkb:Q9UJY0|intact:EBI-2559594|intact:EBI-718302|uniprotkb:B2RDC1|uniprotkb:Q5PU80|intact:EBI-28973725|ensembl:ENSP00000395772.1	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:gnl3_human(display_long)|uniprotkb:Nucleolar GTP-binding protein 3(gene name synonym)|uniprotkb:Nucleostemin(gene name synonym)|uniprotkb:E2-induced gene 3 protein(gene name synonym)|uniprotkb:Novel nucleolar protein 47(gene name synonym)|uniprotkb:GNL3(gene name)|psi-mi:GNL3(display_short)|uniprotkb:E2IG3(gene name synonym)|uniprotkb:NS(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_055181.3|refseq:NP_996561.1|refseq:NP_996562.1|ensembl:ENSG00000163938.17(gene)|ensembl:ENST00000418458.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0017145""(stem cell division)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0030496""(midbody)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0033235""(positive regulation of protein sumoylation)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904816""(positive regulation of protein localization to chromosome, telomeric region)|interpro:IPR006073(GTP1/OBG)|interpro:IPR014813(GNL3L/Grn1 putative GTPase)|interpro:IPR027417|interpro:IPR030378|interpro:IPR050755|mint:Q9BVP2|rcsb pdb:8FKP|rcsb pdb:8FKR|rcsb pdb:8FKT|rcsb pdb:8FKU|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|rcsb pdb:8FKZ|rcsb pdb:8FL0|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8INK|rcsb pdb:8IPD|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR1|rcsb pdb:8IR3|reactome:R-HSA-6791226|panther:PTHR11089(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:c1DgvQoZ51edxvnCa6GFhfNRR7M9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q9NVP1	intact:EBI-11477981	intact:EBI-724378|uniprotkb:Q6GTZ9|uniprotkb:Q6IAU4|uniprotkb:Q92732|uniprotkb:Q9BQB7|ensembl:ENSP00000263239.2	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:ddx18_human(display_long)|uniprotkb:DEAD box protein 18(gene name synonym)|uniprotkb:Myc-regulated DEAD box protein(gene name synonym)|uniprotkb:DDX18(gene name)|psi-mi:DDX18(display_short)|uniprotkb:cPERP-D(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_006764.3|ensembl:ENSG00000088205.13(gene)|ensembl:ENST00000263239.7(transcript)|go:""GO:0000463""(""maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR025313|interpro:IPR027417|interpro:IPR044773|mint:Q9NVP1|rcsb pdb:3LY5|rcsb pdb:8FKP|rcsb pdb:8FKQ|rcsb pdb:8FKR|rcsb pdb:8FKS|rcsb pdb:8FKT|rcsb pdb:8FKU|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|panther:PTHR24031(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:RmupZbt33/w1V7Uq5vnRO36j2Tc9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:P59998	intact:EBI-11477981	intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|uniprotkb:F6TTL5|ensembl:ENSP00000380431.2	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"efo:""Orphanet:662762""|ensembl:ENSG00000241553.13(gene)|ensembl:ENST00000397261.8(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0019899""(enzyme binding)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042995""(cell projection)|go:""GO:0045010""(actin nucleation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|refseq:NP_001185709.1|refseq:NP_005709.1|dip:DIP-33188N|panther:PTHR22629(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q9NYF8	intact:EBI-10762386	intact:EBI-437804|ensembl:ENSP00000435210.1|uniprotkb:Q86WY0|uniprotkb:Q14673|uniprotkb:Q86WU6|uniprotkb:B7ZM58|uniprotkb:A2RU75|uniprotkb:E1P586	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:bclf1_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 1(gene name synonym)|uniprotkb:BCLAF1(gene name)|psi-mi:BCLAF1(display_short)|uniprotkb:BTF(gene name synonym)|uniprotkb:KIAA0164(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"ensembl:ENSG00000029363.17(gene)|ensembl:ENST00000531224.6(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0016592""(mediator complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR029199|mint:Q9NYF8|rcsb pdb:7RJN|rcsb pdb:7RJR|refseq:NP_001070908.1|refseq:NP_001070909.1|refseq:NP_055554.1|refseq:NP_001287967.1|panther:PTHR15268(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:v6qbjyjKVCv0B/olkjQfTPKWqBw9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q9Y2W1	intact:EBI-10762386	intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634.5|ensembl:ENSP00000433825.1	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_005110.2|refseq:NP_001308400.1|refseq:NP_001308402.1|ensembl:ENSG00000054118.15(gene)|ensembl:ENST00000354618.10(transcript)|ensembl:ENST00000469141.6(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016592""(mediator complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0042753""(positive regulation of circadian rhythm)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|panther:PTHR15268(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:O60583	intact:EBI-10762386	intact:EBI-2836757|uniprotkb:Q5I1Y0|uniprotkb:A8KA48|uniprotkb:Q29R66|uniprotkb:Q53SR4|uniprotkb:O60582|ensembl:ENSP00000264157.5|uniprotkb:D3DP73|uniprotkb:D3DP74	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:ccnt2_human(display_long)|uniprotkb:CCNT2(gene name)|psi-mi:CCNT2(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"ensembl:ENSG00000082258.13(gene)|ensembl:ENST00000264157.10(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0008024""(cyclin/CDK positive transcription elongation factor complex)|go:""GO:0019085""(early viral transcription)|go:""GO:0019086""(late viral transcription)|go:""GO:0019901""(protein kinase binding)|go:""GO:0032786""(positive regulation of DNA-templated transcription, elongation)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051147""(regulation of muscle cell differentiation)|go:""GO:0051301""(cell division)|go:""GO:0061575""(cyclin-dependent protein serine/threonine kinase activator activity)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0097322""(7SK snRNA binding)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|interpro:IPR047321|interpro:IPR047322|mint:O60583|rcsb pdb:2IVX|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|refseq:NP_001232.1|refseq:NP_490595.1|panther:PTHR10026(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:v1mUPCNA+Plg8UioUhIj1LL52fI9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:P08670	intact:EBI-10762386	intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|ensembl:ENSP00000224237.5|ensembl:ENSP00000446007.1|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"efo:""Orphanet:675396""|ensembl:ENSG00000026025.16(gene)|ensembl:ENST00000224237.9(transcript)|ensembl:ENST00000544301.7(transcript)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005212""(structural constituent of eye lens)|go:""GO:0005737""(cytoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0014002""(astrocyte development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030424""(axon)|go:""GO:0031175""(neuron projection development)|go:""GO:0031252""(cell leading edge)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0045109""(intermediate filament organization)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070307""(lens fiber cell development)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071225""(cellular response to muramyl dipeptide)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0097110""(scaffold protein binding)|go:""GO:1990254""(keratin filament binding)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|interpro:IPR050405|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|rcsb pdb:8RVE|rcsb pdb:8TRQ|rcsb pdb:8TRR|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:NP_003371.2|refseq:XP_006717563.1|efo:""Orphanet:98984""|dip:DIP-32507N|panther:PTHR45652(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:P43243	intact:EBI-10762386	intact:EBI-352602|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5|ensembl:ENSP00000378284.3|ensembl:ENSP00000482895.1	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"ensembl:ENSG00000015479.20(gene)|ensembl:ENST00000394805.8(transcript)|ensembl:ENST00000618441.5(transcript)|go:""GO:0001825""(blastocyst formation)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003170""(heart valve development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005634""(nucleus)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_001181885.1|refseq:NP_001269207.1|refseq:NP_061322.2|refseq:NP_954659.1|efo:""Orphanet:600""|efo:""Orphanet:803""|panther:PTHR15592(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:P98175	intact:EBI-10762386	intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|ensembl:ENSP00000366829.3|uniprotkb:A0A0A0MR66	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"efo:""Orphanet:2886""|ensembl:ENSG00000182872.16(gene)|ensembl:ENST00000377604.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048025""(negative regulation of mRNA splicing, via spliceosome)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1905288""(vascular associated smooth muscle cell apoptotic process)|go:""GO:1905461""(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:""GO:1990874""(vascular associated smooth muscle cell proliferation)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_001191397.1|refseq:NP_005667.2|refseq:NP_690595.1|panther:PTHR13948(orthology-group)|ensembl:ENST00000329236.8|ensembl:ENSP00000328848.8|ensembl:ENST00000345781.10|ensembl:ENSP00000329659.6|ensembl:ENSP00000366829.3|ensembl:ENST00000628161.2|ensembl:ENSP00000486115.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:O43143	intact:EBI-10762386	intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741.4	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym)|uniprotkb:Splicing factor Prp43(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_001349.2|ensembl:ENSG00000109606.13(gene)|ensembl:ENST00000336812.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005689""(U12-type spliceosomal complex)|go:""GO:0005730""(nucleolus)|go:""GO:0006397""(mRNA processing)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0008380""(RNA splicing)|go:""GO:0009636""(response to toxic substance)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043279""(response to alkaloid)|go:""GO:0051607""(defense response to virus)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|interpro:IPR048333|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|rcsb pdb:8EJM|rcsb pdb:8RO2|reactome:R-HSA-72163|dip:DIP-38211N|panther:PTHR18934(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q07666	intact:EBI-10762386	intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829.7	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|panther:PTHR11208(orthology-group)|ensembl:ENSG00000121774.18(gene)|ensembl:ENST00000327300.12(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0016020""(membrane)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046831""(regulation of RNA export from nucleus)|go:""GO:0046833""(positive regulation of RNA export from nucleus)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070618""(Grb2-Sos complex)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|interpro:IPR045071|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|rcsb pdb:7Z89|rcsb pdb:7Z8A|rcsb pdb:7Z9A|rcsb pdb:7Z9B|rcsb pdb:7ZAB|rcsb pdb:7ZAC|rcsb pdb:7ZAF|rcsb pdb:7ZAM|reactome:R-HSA-8849468"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:P23246	intact:EBI-10762386	intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748.5	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"efo:""Orphanet:319308""|ensembl:ENSG00000116560.12(gene)|ensembl:ENST00000357214.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0042382""(paraspeckles)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042754""(negative regulation of circadian rhythm)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1902177""(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|rcsb pdb:7PU5|rcsb pdb:7SP0|rcsb pdb:7UJ1|rcsb pdb:7UK1|reactome:R-HSA-8849468|reactome:R-HSA-9635465|refseq:NP_005057.1|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N|panther:PTHR23189(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:O43290	intact:EBI-10762386	intact:EBI-607761|uniprotkb:A6NDN1|uniprotkb:Q53GB5|ensembl:ENSP00000310448.5	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:snut1_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 110 kDa protein(gene name synonym)|uniprotkb:SART1(gene name)|psi-mi:SART1(display_short)|uniprotkb:SNU66 homolog(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_005137.1|ensembl:ENSG00000175467.15(gene)|ensembl:ENST00000312397.10(transcript)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000481""(maturation of 5S rRNA)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0015030""(Cajal body)|go:""GO:0016607""(nuclear speck)|go:""GO:0045292""(mRNA cis splicing, via spliceosome)|go:""GO:0045585""(positive regulation of cytotoxic T cell differentiation)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|interpro:IPR005011(SART-1 protein)|interpro:IPR045347|mint:O43290|rcsb pdb:4PYU|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8Q7N|rcsb pdb:8QO9|rcsb pdb:8QOZ|rcsb pdb:8QP8|rcsb pdb:8QP9|rcsb pdb:8QPA|rcsb pdb:8QPB|rcsb pdb:8QPE|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RM5|rcsb pdb:8Y6O|reactome:R-HSA-72163|dip:DIP-33360N|panther:PTHR14152(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:egvWHy7UXW+MkGtGEW984yvRU9k9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q15750	intact:EBI-10762386	intact:EBI-358643|uniprotkb:Q2PP09|intact:EBI-3959873|uniprotkb:Q8IZW2|ensembl:ENSP00000216160.6	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:tab1_human(display_long)|uniprotkb:TAB1(gene name)|psi-mi:TAB1(display_short)|uniprotkb:MAP3K7IP1(gene name synonym)|uniprotkb:TGF-beta-activated kinase 1-binding protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase 7-interacting protein 1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_006107.1|refseq:NP_705717.1|ensembl:ENSG00000100324.14(gene)|ensembl:ENST00000216160.11(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003279""(cardiac septum development)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0010008""(endosome membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030324""(lung development)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035904""(aorta development)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0048273""(mitogen-activated protein kinase p38 binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060976""(coronary vasculature development)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0141111""(positive regulation of cGAS/STING signaling pathway)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q15750|rcsb pdb:2J4O|rcsb pdb:2POM|rcsb pdb:2POP|rcsb pdb:2YDS|rcsb pdb:2YIY|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4GS6|rcsb pdb:4KA3|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5DIY|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5NZZ|rcsb pdb:5O90|rcsb pdb:5V5N|rcsb pdb:5VVU|rcsb pdb:7NTH|rcsb pdb:7NTI|rcsb pdb:8GW3|rcsb pdb:8XI8|reactome:R-HSA-168638|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-9705671|reactome:R-HSA-975163|dip:DIP-27524N|panther:PTHR13832(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:28+bzs6bpXJTun4XukxC/7oAYSs9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:P52756	intact:EBI-10762386	intact:EBI-714003|uniprotkb:Q93021|uniprotkb:Q9BU14|uniprotkb:Q9UKY8|uniprotkb:Q9UL24|uniprotkb:B2RA45|uniprotkb:B4DM16|uniprotkb:B4DMF9|uniprotkb:B4DZ63|uniprotkb:Q9HDA6|ensembl:ENSP00000343054.3|intact:EBI-16431417	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:rbm5_human(display_long)|uniprotkb:RNA-binding motif protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor LUCA15(gene name synonym)|uniprotkb:Protein G15(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-9(gene name synonym)|uniprotkb:RBM5(gene name)|psi-mi:RBM5(display_short)|uniprotkb:H37(orf name)|uniprotkb:LUCA15(orf name)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_005769.1|ensembl:ENSG00000003756.17(gene)|ensembl:ENST00000347869.8(transcript)|go:""GO:0000245""(spliceosomal complex assembly)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006396""(RNA processing)|go:""GO:0006915""(apoptotic process)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034991|interpro:IPR034993|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P52756|rcsb pdb:2LK0|rcsb pdb:2LK1|rcsb pdb:2LKZ|rcsb pdb:5MF9|rcsb pdb:5MFY|rcsb pdb:7PCV|rcsb pdb:7PDV|reactome:R-HSA-72163|refseq:XP_016860992.1|dip:DIP-47277N|panther:PTHR13948(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:LsPTpaKrGY2xtpYofHbFVXjSi/A9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q9P2N5	intact:EBI-10762386	intact:EBI-2801823|uniprotkb:Q8IYW9|ensembl:ENSP00000265271.5	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:rbm27_human(display_long)|uniprotkb:KIAA1311(gene name synonym)|uniprotkb:RNA-binding motif protein 27(gene name synonym)|uniprotkb:RBM27(gene name)|psi-mi:RBM27(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_061862.1|ensembl:ENSG00000091009.8(gene)|ensembl:ENST00000265271.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0016607""(nuclear speck)|go:""GO:0046872""(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034451|interpro:IPR035979|interpro:IPR045137|mint:Q9P2N5|panther:PTHR14398(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:TOeh1JAElLGeLfz+YkgWIsS4V0k9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q0ZGT2	intact:EBI-10762386	intact:EBI-351705|uniprotkb:B4DPZ7|uniprotkb:A0PJ84|uniprotkb:Q0D2H2|uniprotkb:Q14CC2|uniprotkb:Q14CC3|uniprotkb:Q16081|uniprotkb:Q7Z2X0|uniprotkb:Q96DL0|uniprotkb:Q9Y2V1|intact:EBI-2555043|ensembl:ENSP00000333938.7	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:nexn_human(display_long)|uniprotkb:F-actin-binding protein(gene name synonym)|uniprotkb:Nelin(gene name synonym)|uniprotkb:NEXN(gene name)|psi-mi:NEXN(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"efo:""Orphanet:154""|ensembl:ENSG00000162614.19(gene)|ensembl:ENST00000334785.12(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007411""(axon guidance)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030018""(Z disc)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0051015""(actin filament binding)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0070593""(dendrite self-avoidance)|go:""GO:0098632""(cell-cell adhesion mediator activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q0ZGT2|refseq:NP_001165780.1|refseq:NP_653174.3|refseq:XP_005271380.1|panther:PTHR10075(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:YtKRiGq1tjrPhdFzpS5TKVn3So89606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q13813	intact:EBI-10762386	intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-28985930|ensembl:ENSP00000361816.4|intact:EBI-4404719	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"efo:""Orphanet:3451""|ensembl:ENSG00000197694.19(gene)|ensembl:ENST00000372731.8(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008091""(spectrin)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042995""(cell projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051693""(actin filament capping)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904724""(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|dip:DIP-33141N|panther:PTHR11915(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:O95218	intact:EBI-10762386	intact:EBI-1051583|intact:EBI-1642120|intact:EBI-1163882|intact:EBI-1166395|uniprotkb:Q53GS3|uniprotkb:Q59F92|uniprotkb:Q5VV33|uniprotkb:Q8IXN6|uniprotkb:Q9UP63|uniprotkb:Q5VV34|uniprotkb:D3DQ75|ensembl:ENSP00000359958.3	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:zrab2_human(display_long)|uniprotkb:ZRANB2(gene name)|psi-mi:ZRANB2(display_short)|uniprotkb:ZIS(gene name synonym)|uniprotkb:ZNF265(gene name synonym)|uniprotkb:Zinc finger protein 265(gene name synonym)|uniprotkb:Zinc finger, splicing(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_005446.2|refseq:NP_976225.1|ensembl:ENSG00000132485.14(gene)|ensembl:ENST00000370920.8(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0046872""(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR017337(Uncharacterised conserved protein UCP037956, zinc finger Ran-binding)|interpro:IPR036443|mint:O95218|rcsb pdb:1N0Z|rcsb pdb:2K1P|rcsb pdb:3G9Y|panther:PTHR12999(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:NSsZyRDwY5bF3I5OGvd1jGYTijY9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:P51532	intact:EBI-10762386	intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896.4|ensembl:ENSP00000395654.1	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"efo:""Orphanet:1465""|efo:""Orphanet:231108""|efo:""Orphanet:370396""|efo:""Orphanet:466962""|ensembl:ENSG00000127616.22(gene)|ensembl:ENST00000344626.10(transcript)|ensembl:ENST00000429416.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0001188""(RNA polymerase I preinitiation complex assembly)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001650""(fibrillar center)|go:""GO:0002039""(p53 binding)|go:""GO:0003407""(neural retina development)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006337""(nucleosome disassembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007399""(nervous system development)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0016787""(hydrolase activity)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042393""(histone binding)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0071564""(npBAF complex)|go:""GO:0071565""(nBAF complex)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140092""(bBAF complex)|go:""GO:0140288""(GBAF complex)|go:""GO:0140658""(ATP-dependent chromatin remodeler activity)|go:""GO:0140750""(nucleosome array spacer activity)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:1902661""(positive regulation of glucose mediated signaling pathway)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|interpro:IPR049730|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|rcsb pdb:7TAB|rcsb pdb:7TD9|rcsb pdb:7VDT|rcsb pdb:7VDV|rcsb pdb:7VRB|rcsb pdb:7Y8R|rcsb pdb:8EB1|rcsb pdb:8G1Q|rcsb pdb:8QJR|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665|reactome:R-HSA-9824585|reactome:R-HSA-9845323|refseq:NP_001122316.1|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|refseq:NP_003063.2|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|dip:DIP-24249N|ensembl:ENSP00000343896.4|ensembl:ENSP00000395654.1|ensembl:ENST00000444061.8|ensembl:ENSP00000392837.2|ensembl:ENST00000541122.6|ensembl:ENSP00000445036.2|ensembl:ENST00000589677.5|ensembl:ENSP00000464778.1|ensembl:ENST00000590574.6|ensembl:ENSP00000466963.1|ensembl:ENST00000643296.1|ensembl:ENSP00000496635.1|ensembl:ENST00000644737.1|ensembl:ENSP00000495548.1|ensembl:ENST00000645460.1|ensembl:ENSP00000494463.1|ensembl:ENST00000646484.1|ensembl:ENSP00000495536.1|ensembl:ENST00000646510.1|ensembl:ENSP00000494772.1|ensembl:ENST00000647230.1|ensembl:ENSP00000494676.1|panther:PTHR10799(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:P11387	intact:EBI-10762386	intact:EBI-876302|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3|ensembl:ENSP00000354522.2	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_003277.1|panther:PTHR10290(orthology-group)|ensembl:ENSG00000198900.7(gene)|ensembl:ENST00000361337.3(transcript)|go:""GO:0000932""(P-body)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001650""(fibrillar center)|go:""GO:0001673""(male germ cell nucleus)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003917""(""DNA topoisomerase type I (single strand cut, ATP-independent) activity"")|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0006260""(DNA replication)|go:""GO:0006265""(DNA topological change)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008301""(DNA binding, bending)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0012501""(programmed cell death)|go:""GO:0016310""(phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0040016""(embryonic cleavage)|go:""GO:0043204""(perikaryon)|go:""GO:0097100""(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|interpro:IPR048045|interpro:IPR051062|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885|dip:DIP-36356N"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q14241	intact:EBI-10762386	intact:EBI-742350|uniprotkb:Q8IXH1|uniprotkb:B2R7Q8|ensembl:ENSP00000484196.2	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:eloa1_human(display_long)|uniprotkb:ELOA(gene name)|psi-mi:ELOA(display_short)|uniprotkb:Elongin 110 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit A1(gene name synonym)|uniprotkb:SIII p110(gene name synonym)|uniprotkb:TCEB3(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 3(gene name synonym)|uniprotkb:MSTP059(orf name)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_003189.2|ensembl:ENSG00000011007.13(gene)|ensembl:ENST00000613537.5(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006367""(transcription initiation at RNA polymerase II promoter)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0070449""(elongin complex)|go:""GO:0090734""(site of DNA damage)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR010684(RNA polymerase II transcription factor SIII, subunit A)|interpro:IPR017923|interpro:IPR035441|interpro:IPR051870|mint:Q14241|rcsb pdb:4HFX|rcsb pdb:6ZUZ|rcsb pdb:8OEV|rcsb pdb:8OEW|rcsb pdb:8OF0|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|panther:PTHR15141(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:xkZC1MGlAqFyhLSjBHPJLqawYeI9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q8N163	intact:EBI-10762386	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|uniprotkb:B2RB79|uniprotkb:D3DSR6|ensembl:ENSP00000310670.4|ensembl:ENSP00000373930.3	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_066997.3|ensembl:ENSG00000158941.17(gene)|ensembl:ENST00000308511.9(transcript)|ensembl:ENST00000389279.7(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005819""(spindle)|go:""GO:0006397""(mRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0008380""(RNA splicing)|go:""GO:0009411""(response to UV)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032784""(regulation of DNA-templated transcription elongation)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0044609""(DBIRD complex)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048511""(rhythmic process)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090311""(regulation of protein deacetylation)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:2000003""(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR045353|interpro:IPR045354|mint:Q8N163|rcsb pdb:8EZ6|reactome:R-HSA-3371453|dip:DIP-38122N"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:P06748	intact:EBI-10762386	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q15233	intact:EBI-10762386	intact:EBI-350527|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3|ensembl:ENSP00000276079.8|ensembl:ENSP00000362947.1|ensembl:ENSP00000406673.2|ensembl:ENSP00000410299.2|ensembl:ENSP00000415777.2|ensembl:ENSP00000503031.1|ensembl:ENSP00000503233.1|ensembl:ENSP00000504314.1|ensembl:ENSP00000504351.1	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"efo:""Orphanet:319308""|efo:""Orphanet:466791""|ensembl:ENSG00000147140.17(gene)|ensembl:ENST00000276079.13(transcript)|ensembl:ENST00000373841.5(transcript)|ensembl:ENST00000420903.6(transcript)|ensembl:ENST00000450092.6(transcript)|ensembl:ENST00000454976.2(transcript)|ensembl:ENST00000677274.1(transcript)|ensembl:ENST00000677446.1(transcript)|ensembl:ENST00000677612.1(transcript)|ensembl:ENST00000678231.1(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0042382""(paraspeckles)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903377""(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|rcsb pdb:7PU5|refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|dip:DIP-29951N|panther:PTHR23189(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q06787	intact:EBI-10762386	intact:EBI-366305|uniprotkb:Q5PQZ6|uniprotkb:Q16578|uniprotkb:Q99054|uniprotkb:A6NNH4|uniprotkb:D3DWT0|uniprotkb:D3DWT1|uniprotkb:D3DWT2|uniprotkb:G8JL90|ensembl:ENSP00000359506.5	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:fmr1_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|uniprotkb:Fragile X messenger ribonucleoprotein(gene name synonym)|uniprotkb:Protein FMR-1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"efo:""Orphanet:261483""|efo:""Orphanet:449291""|efo:""Orphanet:642691""|efo:""Orphanet:908""|efo:""Orphanet:93256""|ensembl:ENSG00000102081.16(gene)|ensembl:ENST00000370475.9(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0002151""(G-quadruplex RNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006397""(mRNA processing)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0007215""(glutamate receptor signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008017""(microtubule binding)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008380""(RNA splicing)|go:""GO:0010369""(chromocenter)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015030""(Cajal body)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030371""(translation repressor activity)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0032433""(filopodium tip)|go:""GO:0033592""(RNA strand annealing activity)|go:""GO:0034046""(""poly(G) binding"")|go:""GO:0034063""(stress granule assembly)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035197""(siRNA binding)|go:""GO:0035198""(miRNA binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042995""(cell projection)|go:""GO:0043005""(neuron projection)|go:""GO:0043022""(ribosome binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0043204""(perikaryon)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0043679""(axon terminus)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044830""(modulation by host of viral RNA genome replication)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045202""(synapse)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0046928""(regulation of neurotransmitter secretion)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0048170""(positive regulation of long-term neuronal synaptic plasticity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048513""(animal organ development)|go:""GO:0051028""(mRNA transport)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0060965""(negative regulation of miRNA-mediated gene silencing)|go:""GO:0060998""(regulation of dendritic spine development)|go:""GO:0060999""(positive regulation of dendritic spine development)|go:""GO:0070840""(dynein complex binding)|go:""GO:0071598""(neuronal ribonucleoprotein granule)|go:""GO:0097386""(glial cell projection)|go:""GO:0098586""(cellular response to virus)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098908""(regulation of neuronal action potential)|go:""GO:0099577""(regulation of translation at presynapse, modulating synaptic transmission)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|go:""GO:1900453""(negative regulation of long-term synaptic depression)|go:""GO:1901254""(positive regulation of intracellular transport of viral material)|go:""GO:1901386""(negative regulation of voltage-gated calcium channel activity)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|go:""GO:1902737""(dendritic filopodium)|go:""GO:1990247""(N6-methyladenosine-containing RNA reader activity)|go:""GO:1990812""(growth cone filopodium)|go:""GO:1990825""(sequence-specific mRNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000301""(negative regulation of synaptic vesicle exocytosis)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|go:""GO:2000766""(negative regulation of cytoplasmic translation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|interpro:IPR047431|interpro:IPR047436|interpro:IPR047438|interpro:IPR047440|mint:Q06787|rcsb pdb:2BKD|rcsb pdb:2FMR|rcsb pdb:2LA5|rcsb pdb:2QND|rcsb pdb:4OVA|rcsb pdb:4QVZ|rcsb pdb:4QW2|rcsb pdb:5DE5|rcsb pdb:5DE8|rcsb pdb:5DEA|rcsb pdb:5UWJ|rcsb pdb:5UWO|refseq:NP_001172004.1|refseq:NP_001172005.1|refseq:NP_001172010.1|refseq:NP_001172011.1|refseq:NP_002015.1|dip:DIP-29509N|panther:PTHR10603(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:+iN/J/MbxTcRwgDezYseEDwLep49606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q5SW79	intact:EBI-10762386	intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500.1|ensembl:ENSP00000483344.1	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702.17(gene)|ensembl:ENSG00000276725.4(gene)|ensembl:ENST00000366542.6(transcript)|ensembl:ENST00000612450.4(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0120103""(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029300|interpro:IPR051176|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N|panther:PTHR15715(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:P42285	intact:EBI-10762386	intact:EBI-347612|ensembl:ENSP00000230640.5|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"ensembl:ENSG00000039123.16(gene)|ensembl:ENST00000230640.10(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000460""(maturation of 5.8S rRNA)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006364""(rRNA processing)|go:""GO:0006401""(RNA catabolic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0016076""(snRNA catabolic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031499""(TRAMP complex)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|interpro:IPR048392|interpro:IPR050699|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|rcsb pdb:7S7B|rcsb pdb:7S7C|rcsb pdb:7Z4Y|rcsb pdb:7Z4Z|rcsb pdb:7Z52|reactome:R-HSA-6791226|reactome:R-HSA-72163|reactome:R-HSA-9843970|refseq:NP_056175.3|panther:PTHR12131(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:O75643	intact:EBI-10762386	intact:EBI-1045395|uniprotkb:O94884|uniprotkb:Q6PX59|uniprotkb:Q8NBE6|uniprotkb:Q96IF2|uniprotkb:Q9H7S0|uniprotkb:Q6NZY0|intact:EBI-1051631|ensembl:ENSP00000317123.5	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:u520_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short)|uniprotkb:HELIC2(gene name synonym)|uniprotkb:KIAA0788(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)|uniprotkb:Activating signal cointegrator 1 complex subunit 3-like 1(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:ASCC3L1(gene name synonym)|uniprotkb:BRR2(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"efo:""Orphanet:791""|dip:DIP-31659N|ensembl:ENSG00000144028.15(gene)|ensembl:ENST00000323853.10(transcript)|go:""GO:0000354""(cis assembly of pre-catalytic spliceosome)|go:""GO:0000388""(""spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)"")|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005682""(U5 snRNP)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071006""(U2-type catalytic step 1 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|interpro:IPR048863|interpro:IPR050474|mint:O75643|rcsb pdb:2Q0Z|rcsb pdb:3JCR|rcsb pdb:4F91|rcsb pdb:4F92|rcsb pdb:4F93|rcsb pdb:4KIT|rcsb pdb:5O9Z|rcsb pdb:5URJ|rcsb pdb:5URK|rcsb pdb:5URM|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8O|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|rcsb pdb:7OS1|rcsb pdb:7OS2|rcsb pdb:7PX3|rcsb pdb:7W5B|rcsb pdb:8BC8|rcsb pdb:8BC9|rcsb pdb:8BCA|rcsb pdb:8BCB|rcsb pdb:8BCC|rcsb pdb:8BCD|rcsb pdb:8BCE|rcsb pdb:8BCF|rcsb pdb:8BCG|rcsb pdb:8BCH|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0W|rcsb pdb:8Q7Q|rcsb pdb:8Q7V|rcsb pdb:8Q7W|rcsb pdb:8Q7X|rcsb pdb:8Q91|rcsb pdb:8QO9|rcsb pdb:8QOZ|rcsb pdb:8QP9|rcsb pdb:8QPA|rcsb pdb:8QPB|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RC0|rcsb pdb:8RM5|rcsb pdb:8Y6O|rcsb pdb:9FMD|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_054733.2|refseq:XP_016859092.1|panther:PTHR24075(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:2ZAcbMfMlk2xWWAiy7MeCL0CHtM9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q9UNX4	intact:EBI-10762386	intact:EBI-727436|ensembl:ENSP00000308179.4	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:wdr3_human(display_long)|uniprotkb:WDR3(gene name)|psi-mi:WDR3(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_006775.1|ensembl:ENSG00000065183.16(gene)|ensembl:ENST00000349139.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0030490""(maturation of SSU-rRNA)|go:""GO:0030515""(snoRNA binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032040""(small-subunit processome)|go:""GO:0034388""(Pwp2p-containing subcomplex of 90S preribosome)|go:""GO:0042274""(ribosomal small subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|interpro:IPR051570|mint:Q9UNX4|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|reactome:R-HSA-6790901|reactome:R-HSA-6791226|panther:PTHR19853(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:aslkTiEP+9ytaN6cc+SC+TzOxUg9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:Q9NZB2	intact:EBI-10762386	intact:EBI-1171960|uniprotkb:A6NGU0|uniprotkb:O60649|uniprotkb:Q14688|uniprotkb:Q4VXF4|uniprotkb:Q4VXF5|uniprotkb:Q4VXG2|uniprotkb:Q96I21|uniprotkb:Q9NZB1|uniprotkb:C4AMC6|uniprotkb:Q86V69|intact:EBI-2560129|ensembl:ENSP00000277165.5	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:f120a_human(display_long)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:Oxidative stress-associated SRC activator(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"refseq:NP_055427.2|refseq:XP_011516714.1|refseq:NP_001273651.1|refseq:NP_001273652.1|refseq:NP_001273653.1|panther:PTHR15976(orthology-group)|ensembl:ENSG00000048828.18(gene)|ensembl:ENST00000277165.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q9NZB2"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZRB2	uniprotkb:P49590	intact:EBI-10762386	intact:EBI-3909030|uniprotkb:B4DDY8|intact:EBI-10988212|ensembl:ENSP00000230771.3|ensembl:ENSP00000494296.1	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:syhm_human(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:HARS2(gene name)|psi-mi:HARS2(display_short)|uniprotkb:HARSL(gene name synonym)|uniprotkb:HARSR(gene name synonym)|uniprotkb:HO3(gene name synonym)|uniprotkb:Histidine--tRNA ligase-like(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033344|imex:IM-29092-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"dip:DIP-59626N|ensembl:ENSG00000112855.17(gene)|ensembl:ENST00000230771.9(transcript)|ensembl:ENST00000645749.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004821""(histidine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0006418""(tRNA aminoacylation for protein translation)|go:""GO:0006427""(histidyl-tRNA aminoacylation)|go:""GO:0042802""(identical protein binding)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|interpro:IPR045864|mint:P49590|reactome:R-HSA-379726|refseq:NP_001265660.1|refseq:NP_001265661.1|refseq:NP_036340.1|efo:""Orphanet:642945""|efo:""Orphanet:642976""|panther:PTHR11476(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/26	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:pp4g+OJKxW3va88iXtfIAnGXMKw9606	intact-crc:76E68CE2960DBA41|rigid:QCkz/BkqLQD+SWvgM5AIFqDsMko	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P04083	intact:EBI-10760263	intact:EBI-354007|ensembl:ENSP00000257497.6|ensembl:ENSP00000366109.1|uniprotkb:B5BU38	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_000691.1|ensembl:ENSG00000135046.15(gene)|ensembl:ENST00000257497.11(transcript)|ensembl:ENST00000376911.2(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002685""(regulation of leukocyte migration)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007187""(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:""GO:0008289""(lipid binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014839""(myoblast migration involved in skeletal muscle regeneration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031514""(motile cilium)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032652""(regulation of interleukin-1 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0033031""(positive regulation of neutrophil apoptotic process)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045627""(positive regulation of T-helper 1 cell differentiation)|go:""GO:0045629""(negative regulation of T-helper 2 cell differentiation)|go:""GO:0045920""(negative regulation of exocytosis)|go:""GO:0046632""(alpha-beta T cell differentiation)|mint:P04083|go:""GO:0046883""(regulation of hormone secretion)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050482""(arachidonate secretion)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071621""(granulocyte chemotaxis)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|refseq:XP_011516911.1|dip:DIP-32875N|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O14818	intact:EBI-10760263	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|ensembl:ENSP00000359910.4|uniprotkb:Q5JXJ2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)|uniprotkb:Proteasome subunit alpha-4(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_002783.1|ensembl:ENSG00000101182.15(gene)|ensembl:ENST00000370873.9(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019773""(proteasome core complex, alpha-subunit complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR050115|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM3|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29363N|panther:PTHR11599(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q8TEA8	intact:EBI-10760263	intact:EBI-4287111|uniprotkb:A8K5X5|uniprotkb:D3DW37|uniprotkb:Q496D1|uniprotkb:Q5W184|uniprotkb:Q8WXU8|uniprotkb:Q9BW67|uniprotkb:Q9H464|uniprotkb:Q9H474|ensembl:ENSP00000366672.4	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	"psi-mi:dtd1_human(display_long)|uniprotkb:DTD1(gene name)|psi-mi:DTD1(display_short)|uniprotkb:C20orf88(gene name synonym)|uniprotkb:HARS2(gene name synonym)|uniprotkb:Histidyl-tRNA synthase-related(gene name synonym)|uniprotkb:""Gly-tRNA(Ala) deacylase""(gene name synonym)|uniprotkb:DNA-unwinding element-binding protein B(gene name synonym)|uniprotkb:DUEB(gene name synonym)"	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_543010.3|refseq:NP_001304972.1|ensembl:ENSG00000125821.13(gene)|ensembl:ENST00000377452.4(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006260""(DNA replication)|go:""GO:0006399""(tRNA metabolic process)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051500""(""D-tyrosyl-tRNA(Tyr) deacylase activity"")|interpro:IPR003732(""D-tyrosyl-tRNA(Tyr) deacylase"")|interpro:IPR023509|mint:Q8TEA8|rcsb pdb:2OKV|panther:PTHR10472(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:xv8w85tCe2A1hPgsPS6wG3peR7I9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P27797	intact:EBI-10760263	intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866.4|ensembl:ENSP00000466037.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000179218.15(gene)|ensembl:ENST00000316448.10(transcript)|ensembl:ENST00000586967.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001849""(complement component C1q complex binding)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005506""(iron ion binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005925""(focal adhesion)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006457""(protein folding)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0022417""(obsolete protein maturation by protein folding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0033018""(sarcoplasmic reticulum lumen)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033574""(response to testosterone)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0036503""(ERAD pathway)|go:""GO:0040020""(regulation of meiotic nuclear division)|go:""GO:0042277""(peptide binding)|go:""GO:0042562""(hormone binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0042921""(nuclear receptor-mediated glucocorticoid signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044194""(cytolytic granule)|go:""GO:0044322""(endoplasmic reticulum quality control compartment)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048387""(negative regulation of retinoic acid receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051208""(sequestering of calcium ion)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060473""(cortical granule)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071257""(cellular response to electrical stimulus)|go:""GO:0071285""(cellular response to lithium ion)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0090398""(cellular senescence)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098586""(cellular response to virus)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140313""(molecular sequestering activity)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901164""(negative regulation of trophoblast cell migration)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901652""(response to peptide)|go:""GO:1903416""(response to glycoside)|go:""GO:1904614""(response to biphenyl)|go:""GO:2000510""(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|rcsb pdb:7QPD|rcsb pdb:8TZO|rcsb pdb:8TZR|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|refseq:NP_004334.1|dip:DIP-104N|efo:""Orphanet:131""|efo:""Orphanet:3318""|efo:""Orphanet:824""|panther:PTHR11073(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P50213	intact:EBI-10760263	intact:EBI-355999|uniprotkb:D3DW83|uniprotkb:Q9H3X0|ensembl:ENSP00000299518.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	"psi-mi:idh3a_human(display_long)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:""NAD(+)-specific ICDH subunit alpha""(gene name synonym)"	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:791""|ensembl:ENSG00000166411.14(gene)|ensembl:ENST00000299518.7(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004449""(""isocitrate dehydrogenase (NAD+) activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006102""(isocitrate metabolic process)|go:""GO:0045242""(""isocitrate dehydrogenase complex (NAD+)"")|go:""GO:0051287""(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P50213|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|rcsb pdb:8GRB|rcsb pdb:8GRD|rcsb pdb:8GRG|rcsb pdb:8GRH|rcsb pdb:8GRU|rcsb pdb:8GS5|reactome:R-HSA-71403|reactome:R-HSA-9837999|refseq:NP_005521.1|panther:PTHR11835(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:JvAUAMJ0DcgnIfvy/vlfRyXYzhE9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P11498	intact:EBI-10760263	intact:EBI-2211322|ensembl:ENSP00000377527.2|ensembl:ENSP00000377530.2|ensembl:ENSP00000377532.1|ensembl:ENSP00000435905.2|ensembl:ENSP00000498302.1|ensembl:ENSP00000498406.1|ensembl:ENSP00000498994.1|uniprotkb:Q16705|uniprotkb:B4DN00	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"rcsb pdb:3BG9|rcsb pdb:7WTA|rcsb pdb:7WTB|rcsb pdb:7WTC|rcsb pdb:7WTD|rcsb pdb:7WTE|rcsb pdb:8HWL|rcsb pdb:8J7O|ensembl:ENSG00000173599.15(gene)|ensembl:ENST00000393955.6(transcript)|ensembl:ENST00000393958.7(transcript)|ensembl:ENST00000393960.7(transcript)|ensembl:ENST00000529047.6(transcript)|ensembl:ENST00000651036.1(transcript)|ensembl:ENST00000651854.1(transcript)|ensembl:ENST00000652125.1(transcript)|go:""GO:0004736""(pyruvate carboxylase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006734""(NADH metabolic process)|go:""GO:0006739""(NADP metabolic process)|go:""GO:0009374""(biotin binding)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0019074""(viral RNA genome packaging)|go:""GO:0019076""(viral release from host cell)|go:""GO:0042802""(identical protein binding)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0046872""(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR055268|mint:P11498|rcsb pdb:3BG3|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263|reactome:R-HSA-70268|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|dip:DIP-46372N|efo:""Orphanet:353308""|efo:""Orphanet:353314""|efo:""Orphanet:353320""|panther:PTHR43778(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P08559	intact:EBI-10760263	intact:EBI-715747|uniprotkb:Q9NP12|uniprotkb:Q9UBJ8|uniprotkb:Q9UBU0|uniprotkb:Q9UNG4|uniprotkb:Q9UNG5|uniprotkb:Q5JPT8|uniprotkb:Q53H41|uniprotkb:B2R5P7|uniprotkb:B7Z3T7|uniprotkb:B7Z3X5|uniprotkb:A5YVE9|ensembl:ENSP00000394382.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:odpa_human(display_long)|uniprotkb:PDHE1-A type I(gene name synonym)|uniprotkb:PDHA1(gene name)|psi-mi:PDHA1(display_short)|uniprotkb:PHE1A(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"dip:DIP-37652N|ensembl:ENSG00000131828.14(gene)|ensembl:ENST00000422285.7(transcript)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006086""(pyruvate decarboxylation to acetyl-CoA)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0034604""(""pyruvate dehydrogenase (NAD+) activity"")|go:""GO:0045254""(pyruvate dehydrogenase complex)|go:""GO:0046872""(metal ion binding)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597(""Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y"")|interpro:IPR029061|interpro:IPR050642|mint:P08559|rcsb pdb:1NI4|rcsb pdb:2OZL|rcsb pdb:3EXE|rcsb pdb:3EXF|rcsb pdb:3EXG|rcsb pdb:3EXH|rcsb pdb:3EXI|rcsb pdb:6CER|rcsb pdb:6CFO|reactome:R-HSA-204174|reactome:R-HSA-5362517|reactome:R-HSA-9837999|reactome:R-HSA-9861559|refseq:NP_000275.1|refseq:NP_001166925.1|refseq:NP_001166926.1|refseq:NP_001166927.1|efo:""Orphanet:79243""|panther:PTHR11516(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:p4PObFZ4cxJW6ICug+jhlgKlEYY9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P11177	intact:EBI-10760263	intact:EBI-1035872|uniprotkb:B2R7L0|uniprotkb:Q6FH45|uniprotkb:Q9BQ27|uniprotkb:Q9UFK3|uniprotkb:B4DDD7|ensembl:ENSP00000307241.6	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:odpb_human(display_long)|uniprotkb:PDHB(gene name)|psi-mi:PDHB(display_short)|uniprotkb:PHE1B(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:255138""|dip:DIP-37651N|ensembl:ENSG00000168291.13(gene)|ensembl:ENST00000302746.11(transcript)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006086""(pyruvate decarboxylation to acetyl-CoA)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0045254""(pyruvate dehydrogenase complex)|go:""GO:0046872""(metal ion binding)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:P11177|rcsb pdb:1NI4|rcsb pdb:2OZL|rcsb pdb:3EXE|rcsb pdb:3EXF|rcsb pdb:3EXG|rcsb pdb:3EXH|rcsb pdb:3EXI|rcsb pdb:6CER|rcsb pdb:6CFO|reactome:R-HSA-204174|reactome:R-HSA-5362517|reactome:R-HSA-9837999|reactome:R-HSA-9861559|refseq:NP_000916.2|refseq:NP_001166939.1|refseq:NP_001302465.1|panther:PTHR11624(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:VnabVXgFi4b43Wl37PzUX3+j4A89606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P09622	intact:EBI-10760263	intact:EBI-353366|ensembl:ENSP00000205402.3|ensembl:ENSP00000390667.1|uniprotkb:Q14131|uniprotkb:Q14167|uniprotkb:Q59EV8|uniprotkb:Q8WTS4|uniprotkb:B2R5X0|uniprotkb:B4DHG0|uniprotkb:B4DT69	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:dldh_human(display_long)|uniprotkb:DLD(gene name)|psi-mi:DLD(display_short)|uniprotkb:GCSL(gene name synonym)|uniprotkb:LAD(gene name synonym)|uniprotkb:PHE3(gene name synonym)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Glycine cleavage system L protein(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000091140.15(gene)|ensembl:ENST00000205402.10(transcript)|ensembl:ENST00000417551.5(transcript)|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006086""(pyruvate decarboxylation to acetyl-CoA)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0006120""(mitochondrial electron transport, NADH to ubiquinone)|go:""GO:0006508""(proteolysis)|go:""GO:0007369""(gastrulation)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0031514""(motile cilium)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0043159""(acrosomal matrix)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|go:""GO:0045254""(pyruvate dehydrogenase complex)|go:""GO:0048240""(sperm capacitation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0160157""(branched-chain alpha-ketoacid dehydrogenase complex)|go:""GO:0160167""(oxoadipate dehydrogenase complex)|go:""GO:1902493""(acetyltransferase complex)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|interpro:IPR050151|mint:P09622|rcsb pdb:1ZMC|rcsb pdb:1ZMD|rcsb pdb:1ZY8|rcsb pdb:2F5Z|rcsb pdb:3RNM|rcsb pdb:5J5Z|rcsb pdb:5NHG|rcsb pdb:6HG8|rcsb pdb:6I4P|rcsb pdb:6I4Q|rcsb pdb:6I4R|rcsb pdb:6I4S|rcsb pdb:6I4T|rcsb pdb:6I4U|rcsb pdb:6I4Z|rcsb pdb:7PSC|rcsb pdb:7ZYT|reactome:R-HSA-204174|reactome:R-HSA-5362517|reactome:R-HSA-6783984|reactome:R-HSA-70895|reactome:R-HSA-9837999|reactome:R-HSA-9853506|reactome:R-HSA-9858328|reactome:R-HSA-9859138|reactome:R-HSA-9861559|reactome:R-HSA-9865113|reactome:R-HSA-9907570|reactome:R-HSA-9912481|reactome:R-HSA-9912529|refseq:NP_000099.2|refseq:NP_001276679.1|refseq:NP_001276680.1|refseq:NP_001276681.1|efo:""Orphanet:2394""|dip:DIP-29027N|panther:PTHR22912(orthology-group)"	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:7613492C516F3835	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:7Yf9KyBWf18686aOXVUwab65rl89606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q13765	intact:EBI-10760263	intact:EBI-712216|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|intact:EBI-25601473|ensembl:ENSP00000349212.3|ensembl:ENSP00000377469.4|ensembl:ENSP00000446801.1|ensembl:ENSP00000447821.1|ensembl:ENSP00000503345.1|uniprotkb:F8VU71	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|ensembl:ENSG00000196531.14(gene)|ensembl:ENST00000356769.7(transcript)|ensembl:ENST00000393891.8(transcript)|ensembl:ENST00000546392.6(transcript)|ensembl:ENST00000552540.5(transcript)|ensembl:ENST00000678066.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003231""(cardiac ventricle development)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005854""(nascent polypeptide-associated complex)|go:""GO:0006412""(translation)|go:""GO:0010664""(negative regulation of striated muscle cell apoptotic process)|go:""GO:0015031""(protein transport)|go:""GO:0042060""(wound healing)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048633""(positive regulation of skeletal muscle tissue growth)|go:""GO:0048742""(regulation of skeletal muscle fiber development)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905551""(negative regulation of protein localization to endoplasmic reticulum)|go:""GO:2000138""(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|rcsb pdb:7QWQ|rcsb pdb:7QWR|rcsb pdb:7QWS|rcsb pdb:8P2K|rcsb pdb:9F1B|rcsb pdb:9F1C|rcsb pdb:9F1D|rcsb pdb:9FQ0|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P31327	intact:EBI-10760263	intact:EBI-536811|uniprotkb:O43774|uniprotkb:Q7Z5I5|ensembl:ENSP00000233072.5|ensembl:ENSP00000500537.1|ensembl:ENSP00000501022.1|ensembl:ENSP00000501073.1|uniprotkb:B7Z818|uniprotkb:Q53TL5|uniprotkb:J3KQL0|uniprotkb:Q59HF8	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:cpsm_human(display_long)|uniprotkb:Carbamoyl-phosphate synthetase I(gene name synonym)|uniprotkb:CPS1(gene name)|psi-mi:CPS1(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000021826.18(gene)|ensembl:ENST00000233072.10(transcript)|ensembl:ENST00000673510.1(transcript)|ensembl:ENST00000673630.1(transcript)|ensembl:ENST00000673711.1(transcript)|go:""GO:0000050""(urea cycle)|go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0004175""(endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005886""(plasma membrane)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0007494""(midgut development)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010043""(response to zinc ion)|go:""GO:0014075""(response to amine)|go:""GO:0016595""(glutamate binding)|go:""GO:0019240""(citrulline biosynthetic process)|go:""GO:0019433""(triglyceride catabolic process)|go:""GO:0030955""(potassium ion binding)|go:""GO:0032094""(response to food)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036094""(small molecule binding)|go:""GO:0042311""(vasodilation)|go:""GO:0042594""(response to starvation)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0043200""(response to amino acid)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046209""(nitric oxide metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050667""(homocysteine metabolic process)|go:""GO:0055081""(monoatomic anion homeostasis)|go:""GO:0060416""(response to growth hormone)|go:""GO:0070365""(hepatocyte differentiation)|go:""GO:0070409""(carbamoyl phosphate biosynthetic process)|go:""GO:0071242""(cellular response to ammonium ion)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0071377""(cellular response to glucagon stimulus)|go:""GO:0071400""(cellular response to oleic acid)|go:""GO:0071548""(response to dexamethasone)|go:""GO:0072341""(modified amino acid binding)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036914|mint:P31327|rcsb pdb:2YVQ|rcsb pdb:4UTR|rcsb pdb:4UTV|rcsb pdb:4UTX|rcsb pdb:4UTZ|rcsb pdb:4UU7|rcsb pdb:4UU8|rcsb pdb:4UUA|rcsb pdb:4UUB|rcsb pdb:5DOT|rcsb pdb:5DOU|rcsb pdb:5OJO|rcsb pdb:6UEL|rcsb pdb:6W2J|reactome:R-HSA-70635|refseq:NP_001116105.1|refseq:NP_001116106.1|refseq:NP_001866.2|refseq:XP_011508943.1|refseq:XP_011508944.1|refseq:XP_011508945.1|refseq:XP_011508946.1|panther:PTHR11405(orthology-group)|efo:""Orphanet:147"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:497s02igPCWuQcU4lVrMpl5SRig9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P51809	intact:EBI-10760263	intact:EBI-1052205|uniprotkb:Q53GY7|uniprotkb:Q7Z409|uniprotkb:Q9H4A7|ensembl:ENSP00000286448.6|ensembl:ENSP00000518622.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:vamp7_human(display_long)|uniprotkb:SYBL1(gene name synonym)|uniprotkb:Synaptobrevin-like protein 1(gene name synonym)|uniprotkb:Tetanus-insensitive VAMP(gene name synonym)|uniprotkb:VAMP7(gene name)|psi-mi:VAMP7(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000124333.16(gene)|ensembl:ENSG00000292366.1(gene)|ensembl:ENST00000286448.12(transcript)|ensembl:ENST00000711260.1(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0030027""(lamellipodium)|go:""GO:0030141""(secretory granule)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031143""(pseudopodium)|go:""GO:0031201""(SNARE complex)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043308""(eosinophil degranulation)|go:""GO:0043312""(neutrophil degranulation)|go:""GO:0043320""(natural killer cell degranulation)|go:""GO:0045202""(synapse)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903595""(positive regulation of histamine secretion by mast cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR051097|mint:P51809|rcsb pdb:2DMW|reactome:R-HSA-199992|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9020591|refseq:NP_001138621.1|refseq:NP_001172112.1|refseq:NP_005629.1|efo:""Orphanet:251510""|panther:PTHR21136(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:iGCiTvDrgrPOV7mOfivnbt02zV89606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P36776	intact:EBI-10760263	intact:EBI-357448|intact:EBI-1054513|uniprotkb:D6W635|uniprotkb:E5KMH8|uniprotkb:P36777|uniprotkb:Q8N8K8|uniprotkb:Q9UQ95|uniprotkb:B3KPH8|uniprotkb:F5GZ27|intact:EBI-10964236|ensembl:ENSP00000353826.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:lonm_human(display_long)|uniprotkb:LONHs(gene name synonym)|uniprotkb:PRSS15(gene name synonym)|uniprotkb:LONP1(gene name)|psi-mi:LONP1(display_short)|uniprotkb:Lon protease-like protein(gene name synonym)|uniprotkb:Mitochondrial ATP-dependent protease Lon(gene name synonym)|uniprotkb:Serine protease 15(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:1458""|efo:""Orphanet:2140""|efo:""Orphanet:79243""|ensembl:ENSG00000196365.12(gene)|ensembl:ENST00000360614.8(transcript)|go:""GO:0000002""(mitochondrial genome maintenance)|go:""GO:0001666""(response to hypoxia)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0009725""(response to hormone)|go:""GO:0010044""(response to aluminum ion)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0032042""(mitochondrial DNA metabolic process)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0042731""(PH domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043531""(ADP binding)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0051880""(G-quadruplex DNA binding)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:0070407""(oxidation-dependent protein catabolic process)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR027065|interpro:IPR027417|interpro:IPR027503|interpro:IPR046336|interpro:IPR054594|mint:P36776|rcsb pdb:2X36|rcsb pdb:6WYS|rcsb pdb:6WZV|rcsb pdb:6X1M|rcsb pdb:6X27|rcsb pdb:7KRZ|rcsb pdb:7KSL|rcsb pdb:7KSM|rcsb pdb:7NFY|rcsb pdb:7NG4|rcsb pdb:7NG5|rcsb pdb:7NGC|rcsb pdb:7NGF|rcsb pdb:7NGL|rcsb pdb:7NGP|rcsb pdb:7NGQ|rcsb pdb:7OXO|rcsb pdb:7P09|rcsb pdb:7P0B|rcsb pdb:7P0M|rcsb pdb:8OJL|rcsb pdb:8OKA|rcsb pdb:8OM7|rcsb pdb:8OVF|rcsb pdb:8OVG|rcsb pdb:9CC0|rcsb pdb:9CC3|reactome:R-HSA-9837999|reactome:R-HSA-9841251|refseq:NP_001263408.1|refseq:NP_001263409.1|refseq:NP_004784.2|panther:PTHR43718(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:quAPz1dZK2XdoE6WMjQJwFtx53o9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P49411	intact:EBI-10760263	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:254925""|ensembl:ENSG00000178952.11(gene)|ensembl:ENST00000313511.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045202""(synapse)|go:""GO:0045471""(response to ethanol)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070125""(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|interpro:IPR050055|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|reactome:R-HSA-9754560|refseq:NP_003312.3|refseq:XP_016879108.1|panther:PTHR43721(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:gmW0HIoZ+8MccQHJ44Lcu2uwCss9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P36957	intact:EBI-10760263	intact:EBI-351007|uniprotkb:Q9BQ32|uniprotkb:Q7LDY7|ensembl:ENSP00000335304.4|intact:EBI-2511564|uniprotkb:B7Z5W8|uniprotkb:E7ESY5	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:odo2_human(display_long)|uniprotkb:DLST(gene name)|psi-mi:DLST(display_short)|uniprotkb:DLTS(gene name synonym)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:29072""|ensembl:ENSG00000119689.15(gene)|ensembl:ENST00000334220.9(transcript)|go:""GO:0004149""(dihydrolipoyllysine-residue succinyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0006104""(succinyl-CoA metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0033512""(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|go:""GO:0160167""(oxoadipate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR050537|mint:P36957|rcsb pdb:6H05|reactome:R-HSA-6783984|reactome:R-HSA-9853506|reactome:R-HSA-9857492|reactome:R-HSA-9858328|refseq:NP_001924.2|panther:PTHR43416(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:lZLUcTHB/dxXBTI/IXnSjyuVmBo9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P40939	intact:EBI-10760263	intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|uniprotkb:Q53T69|uniprotkb:Q53TA2|ensembl:ENSP00000370023.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:243367""|efo:""Orphanet:5""|efo:""Orphanet:746""|ensembl:ENSG00000084754.12(gene)|ensembl:ENST00000380649.8(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0003857""(3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0003985""(acetyl-CoA C-acetyltransferase activity)|go:""GO:0004300""(enoyl-CoA hydratase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016507""(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:""GO:0016509""(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0018812""(3-hydroxyacyl-CoA dehydratase activity)|go:""GO:0032868""(response to insulin)|go:""GO:0035965""(cardiolipin acyl-chain remodeling)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070403""(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|interpro:IPR050136|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:NP_000173.2|panther:PTHR43612(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O76031	intact:EBI-10760263	intact:EBI-1052667|uniprotkb:A1L428|uniprotkb:A8K8F1|uniprotkb:Q9H4D9|uniprotkb:B9EGI8|ensembl:ENSP00000300107.3|intact:EBI-21353170	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:clpx_human(display_long)|uniprotkb:CLPX(gene name)|psi-mi:CLPX(display_short)|uniprotkb:ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial(gene name synonym)|uniprotkb:Caseinolytic mitochondrial matrix peptidase chaperone subunit X(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_006651.2|dip:DIP-50293N|ensembl:ENSG00000166855.9(gene)|ensembl:ENST00000300107.7(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009368""(endopeptidase Clp complex)|go:""GO:0009841""(mitochondrial endopeptidase Clp complex)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|interpro:IPR050052|mint:O76031|reactome:R-HSA-9837999|panther:PTHR48102(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:+SOis7raPEZqqeel6Y6dOWJcLj49606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9NSE4	intact:EBI-10760263	intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:436174""|ensembl:ENSG00000067704.10(gene)|ensembl:ENST00000366922.3(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004822""(isoleucine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006418""(tRNA aminoacylation for protein translation)|go:""GO:0006428""(isoleucyl-tRNA aminoacylation)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|interpro:IPR050081|mint:Q9NSE4|reactome:R-HSA-379726|reactome:R-HSA-9837999|refseq:NP_060530.3|panther:PTHR42765(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q6PI48	intact:EBI-10760263	intact:EBI-3917045|ensembl:ENSP00000497569.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:sydm_human(display_long)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:DARS2(gene name)|psi-mi:DARS2(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000117593.12(gene)|ensembl:ENST00000649689.2(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0004815""(aspartate-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006422""(aspartyl-tRNA aminoacylation)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043039""(tRNA aminoacylation)|go:""GO:0050560""(""aspartate-tRNA(Asn) ligase activity"")|go:""GO:0070145""(mitochondrial asparaginyl-tRNA aminoacylation)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR029351|interpro:IPR045864|interpro:IPR047089|interpro:IPR047090|mint:Q6PI48|rcsb pdb:4AH6|reactome:R-HSA-379726|refseq:NP_060592.2|efo:""Orphanet:137898""|panther:PTHR22594(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:6tNhPqrlJ5dCXoDIgUjcUB/gA7s9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P34897	intact:EBI-10760263	intact:EBI-352908|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43|ensembl:ENSP00000333667.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1|rcsb pdb:5V7I|ensembl:ENSG00000182199.11(gene)|ensembl:ENST00000328923.8(transcript)|go:""GO:0002082""(regulation of oxidative phosphorylation)|go:""GO:0003682""(chromatin binding)|go:""GO:0004372""(glycine hydroxymethyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006544""(glycine metabolic process)|go:""GO:0006563""(L-serine metabolic process)|go:""GO:0006564""(L-serine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008732""(L-allo-threonine aldolase activity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016597""(amino acid binding)|go:""GO:0019264""(glycine biosynthetic process from serine)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0034340""(response to type I interferon)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0042802""(identical protein binding)|go:""GO:0046653""(tetrahydrofolate metabolic process)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070129""(regulation of mitochondrial translation)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0070552""(BRISC complex)|go:""GO:1903715""(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|interpro:IPR049943|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|rcsb pdb:7BYI|rcsb pdb:8AQL|rcsb pdb:8FJT|rcsb pdb:8FJU|rcsb pdb:8GKS|rcsb pdb:8GKT|rcsb pdb:8GKU|rcsb pdb:8GKW|rcsb pdb:8GKY|rcsb pdb:8GKZ|rcsb pdb:8QI7|rcsb pdb:8SSJ|rcsb pdb:8T4O|rcsb pdb:8T4P|rcsb pdb:8TLC|rcsb pdb:9BOX|reactome:R-HSA-196757|reactome:R-HSA-9013408|reactome:R-HSA-9837999|panther:PTHR11680(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O94925	intact:EBI-10760263	intact:EBI-1043737|uniprotkb:Q9UL05|uniprotkb:Q9UL06|uniprotkb:Q9UL07|uniprotkb:Q9UN40|ensembl:ENSP00000317379.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:glsk_human(display_long)|uniprotkb:GLS(gene name)|psi-mi:GLS(display_short)|uniprotkb:GLS1(gene name synonym)|uniprotkb:KIAA0838(gene name synonym)|uniprotkb:L-glutamine amidohydrolase(gene name synonym)|uniprotkb:K-glutaminase(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000115419.14(gene)|ensembl:ENST00000320717.8(transcript)|go:""GO:0001967""(suckling behavior)|go:""GO:0002087""(regulation of respiratory gaseous exchange by nervous system process)|go:""GO:0004359""(glutaminase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006543""(glutamine catabolic process)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0045202""(synapse)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0090461""(intracellular glutamate homeostasis)|interpro:IPR002110(Ankyrin)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR036770|interpro:IPR041541|mint:O94925|rcsb pdb:3CZD|rcsb pdb:3UNW|rcsb pdb:3UO9|rcsb pdb:3VOY|rcsb pdb:3VOZ|rcsb pdb:3VP0|rcsb pdb:3VP1|rcsb pdb:3VP2|rcsb pdb:3VP3|rcsb pdb:3VP4|rcsb pdb:4O7D|rcsb pdb:5D3O|rcsb pdb:5FI2|rcsb pdb:5FI6|rcsb pdb:5FI7|rcsb pdb:5HL1|rcsb pdb:5I94|rcsb pdb:5JYO|rcsb pdb:5JYP|rcsb pdb:5U0I|rcsb pdb:5U0J|rcsb pdb:5UQE|rcsb pdb:5WJ6|rcsb pdb:6LOX|rcsb pdb:6UJG|rcsb pdb:6UJM|rcsb pdb:6UK6|rcsb pdb:6UKB|rcsb pdb:6UL9|rcsb pdb:6ULA|rcsb pdb:6ULJ|rcsb pdb:6UMC|rcsb pdb:6UMD|rcsb pdb:6UME|rcsb pdb:6UMF|rcsb pdb:7REN|rcsb pdb:7RGG|rcsb pdb:7SBM|rcsb pdb:7SBN|rcsb pdb:8BSK|rcsb pdb:8BSL|rcsb pdb:8BSM|rcsb pdb:8BSN|rcsb pdb:8GWR|rcsb pdb:8IMA|rcsb pdb:8IMB|rcsb pdb:8JUB|rcsb pdb:8JUE|rcsb pdb:8SZJ|reactome:R-HSA-210500|reactome:R-HSA-5628897|reactome:R-HSA-8964539|refseq:NP_001243239.1|refseq:NP_055720.3|efo:""Orphanet:557056""|efo:""Orphanet:557064""|dip:DIP-50591N|panther:PTHR12544(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:IV2jY1Qj63eTVPmTndDavjoUM2w9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P00367	intact:EBI-10760263	intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865.4|uniprotkb:B3KV55|uniprotkb:B4DGN5	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:35878""|ensembl:ENSG00000148672.10(gene)|ensembl:ENST00000277865.5(transcript)|go:""GO:0004352""(""glutamate dehydrogenase (NAD+) activity"")|go:""GO:0004353""(""glutamate dehydrogenase [NAD(P)+] activity"")|go:""GO:0004354""(""glutamate dehydrogenase (NADP+) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006538""(glutamate catabolic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043531""(ADP binding)|go:""GO:0070403""(NAD+ binding)|go:""GO:0070728""(L-leucine binding)|go:""GO:0072350""(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|interpro:IPR046346|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|rcsb pdb:7UZM|rcsb pdb:8KGY|rcsb pdb:8SK8|rcsb pdb:8W4J|reactome:R-HSA-2151201|reactome:R-HSA-8964539|reactome:R-HSA-9837999|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|refseq:NP_005262.1|panther:PTHR11606(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q14697	intact:EBI-10760263	intact:EBI-348004|uniprotkb:A6NC20|uniprotkb:Q8WTS9|uniprotkb:Q9P0X0|ensembl:ENSP00000349053.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:ganab_human(display_long)|uniprotkb:GANAB(gene name)|psi-mi:GANAB(display_short)|uniprotkb:G2AN(gene name synonym)|uniprotkb:KIAA0088(gene name synonym)|uniprotkb:Glucosidase II subunit alpha(gene name synonym)|uniprotkb:Alpha-glucosidase 2(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000089597.18(gene)|ensembl:ENST00000356638.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006491""(N-glycan processing)|go:""GO:0016020""(membrane)|go:""GO:0017177""(glucosidase II complex)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0033919""(glucan 1,3-alpha-glucosidase activity)|go:""GO:0042470""(melanosome)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090599""(alpha-glucosidase activity)|go:""GO:0106407""(Glc2Man9GlcNAc2 oligosaccharide glucosidase activity)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|interpro:IPR048395|mint:Q14697|rcsb pdb:8D43|rcsb pdb:8EMR|reactome:R-HSA-532668|reactome:R-HSA-901042|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:NP_001265121.1|refseq:NP_001265122.1|refseq:NP_001265123.1|refseq:NP_938148.1|refseq:NP_938149.2|panther:PTHR22762(orthology-group)|efo:""Orphanet:730"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:663u1GYwNTZrodoVqwzFjSDGCqs9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q4G0N4	intact:EBI-10760263	intact:EBI-10714975|ensembl:ENSP00000371362.4|uniprotkb:B5MC93|uniprotkb:Q6UTX5|uniprotkb:Q96NM0	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:nakd2_human(display_long)|uniprotkb:Mitochondrial NAD kinase(gene name synonym)|uniprotkb:NAD kinase domain-containing protein 1, mitochondrial(gene name synonym)|uniprotkb:NADK2(gene name)|psi-mi:NADK2(display_short)|uniprotkb:C5orf33(gene name synonym)|uniprotkb:MNADK(gene name synonym)|uniprotkb:NADKD1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:431361""|ensembl:ENSG00000152620.13(gene)|ensembl:ENST00000381937.9(transcript)|go:""GO:0003951""(NAD+ kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006741""(NADP biosynthetic process)|go:""GO:0019674""(NAD metabolic process)|go:""GO:0042803""(protein homodimerization activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR012355(ATP-NAD kinase-like, eukaryotic)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:Q4G0N4|rcsb pdb:7N29|rcsb pdb:7R4J|rcsb pdb:7R4K|rcsb pdb:7R4L|rcsb pdb:7R4M|reactome:R-HSA-196807|reactome:R-HSA-9837999|refseq:NP_001078880.1|refseq:NP_001274269.1|refseq:NP_001274270.1|refseq:NP_694558.1|panther:PTHR13158(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:FuMnD0CG7LLYTwuSzpavlen42iI9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q99714	intact:EBI-10760263	intact:EBI-79964|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9|ensembl:ENSP00000168216.6	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	"psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:""3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))""(gene name synonym)|uniprotkb:""3alpha(or 20beta)-hydroxysteroid dehydrogenase""(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)"	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR43658(orthology-group)|efo:""Orphanet:391428""|efo:""Orphanet:391457""|efo:""Orphanet:85295""|ensembl:ENSG00000072506.14(gene)|ensembl:ENST00000168216.11(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003857""(3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0004303""(""estradiol 17-beta-dehydrogenase [NAD(P)+] activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005886""(plasma membrane)|go:""GO:0006550""(isoleucine catabolic process)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008207""(C21-steroid hormone metabolic process)|go:""GO:0008209""(androgen metabolic process)|go:""GO:0008210""(estrogen metabolic process)|go:""GO:0008709""(""cholate 7-alpha-dehydrogenase (NAD+) activity"")|go:""GO:0030283""(""testosterone dehydrogenase [NAD(P)+] activity"")|go:""GO:0030678""(mitochondrial ribonuclease P complex)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0043527""(tRNA methyltransferase complex)|go:""GO:0044594""(""17-beta-hydroxysteroid dehydrogenase (NAD+) activity"")|go:""GO:0047015""(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:""GO:0047035""(""testosterone dehydrogenase (NAD+) activity"")|go:""GO:0047044""(""androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity"")|go:""GO:0051289""(protein homotetramerization)|go:""GO:0062173""(brexanolone metabolic process)|go:""GO:0070901""(mitochondrial tRNA methylation)|go:""GO:0097745""(mitochondrial tRNA 5'-end processing)|go:""GO:0106281""(""chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity"")|go:""GO:0106282""(""isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity"")|go:""GO:0106283""(""ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity"")|go:""GO:1990180""(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1SO8|rcsb pdb:1U7T|rcsb pdb:2O23|rcsb pdb:7ONU|rcsb pdb:8CBK|rcsb pdb:8CBL|rcsb pdb:8CBM|rcsb pdb:8CBO|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|reactome:R-HSA-9837999|refseq:NP_001032900.1|refseq:NP_004484.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P35232	intact:EBI-10760263	intact:EBI-354213|uniprotkb:Q4VBQ0|ensembl:ENSP00000300408.3|ensembl:ENSP00000393320.3|ensembl:ENSP00000422182.3|ensembl:ENSP00000425035.2|ensembl:ENSP00000426433.3|ensembl:ENSP00000479488.1|ensembl:ENSP00000484113.1|uniprotkb:B4DY47	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:phb1_human(display_long)|uniprotkb:PHB1(gene name)|psi-mi:PHB1(display_short)|uniprotkb:PHB(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001268426.1|refseq:NP_002625.1|ensembl:ENSG00000167085.14(gene)|ensembl:ENST00000300408.8(transcript)|ensembl:ENST00000419140.7(transcript)|ensembl:ENST00000504124.6(transcript)|ensembl:ENST00000511832.6(transcript)|ensembl:ENST00000512041.7(transcript)|ensembl:ENST00000614445.5(transcript)|ensembl:ENST00000617874.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001850""(complement component C3a binding)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031871""(proteinase activated receptor binding)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0035632""(mitochondrial prohibitin complex)|go:""GO:0039529""(RIG-I signaling pathway)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0042113""(B cell activation)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044830""(modulation by host of viral RNA genome replication)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045917""(positive regulation of complement activation)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071897""(DNA biosynthetic process)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:2000323""(negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|panther:PTHR23222(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q99623	intact:EBI-10760263	intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875.1|uniprotkb:B4DP75	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001138303.1|refseq:NP_001254629.1|ensembl:ENSG00000215021.10(gene)|ensembl:ENST00000535923.6(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0009986""(cell surface)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030424""(axon)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0031536""(positive regulation of exit from mitosis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033147""(negative regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0033218""(amide binding)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0033600""(negative regulation of mammary gland epithelial cell proliferation)|go:""GO:0035632""(mitochondrial prohibitin complex)|go:""GO:0039529""(RIG-I signaling pathway)|go:""GO:0042113""(B cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046625""(sphingolipid binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050821""(protein stabilization)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060744""(mammary gland branching involved in thelarche)|go:""GO:0060749""(mammary gland alveolus development)|go:""GO:0060762""(regulation of branching involved in mammary gland duct morphogenesis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071944""(cell periphery)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1900208""(regulation of cardiolipin metabolic process)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902808""(positive regulation of cell cycle G1/S phase transition)|go:""GO:1904959""(regulation of cytochrome-c oxidase activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|rcsb pdb:8J4I|reactome:R-HSA-8949664|reactome:R-HSA-9840373|panther:PTHR23222(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:h4pib54mBeQgOKCe/hib58LM26w9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9NP58	intact:EBI-10760263	intact:EBI-2115230|uniprotkb:O75542|uniprotkb:Q49A66|uniprotkb:Q59GQ5|uniprotkb:Q6ZME6|uniprotkb:Q96ME8|uniprotkb:Q9HAQ6|uniprotkb:Q9HAQ7|ensembl:ENSP00000265316.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:abcb6_human(display_long)|uniprotkb:ABCB6(gene name)|psi-mi:ABCB6(display_short)|uniprotkb:MTABC3(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:UMAT(gene name synonym)|uniprotkb:Mitochondrial ABC transporter 3(gene name synonym)|uniprotkb:Ubiquitously-expressed mammalian ABC half transporter(gene name synonym)|uniprotkb:P-glycoprotein-related protein(gene name synonym)|uniprotkb:ABC-type heme transporter ABCB6(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24221(orthology-group)|ensembl:ENSG00000115657.14(gene)|ensembl:ENST00000265316.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005740""(mitochondrial envelope)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006778""(porphyrin-containing compound metabolic process)|go:""GO:0006779""(porphyrin-containing compound biosynthetic process)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007420""(brain development)|go:""GO:0015439""(ABC-type heme transporter activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:0015886""(heme transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0020037""(heme binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033013""(tetrapyrrole metabolic process)|go:""GO:0033162""(melanosome membrane)|go:""GO:0035351""(heme transmembrane transport)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0042168""(heme metabolic process)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|go:""GO:0043588""(skin development)|go:""GO:0046906""(tetrapyrrole binding)|go:""GO:0055085""(transmembrane transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098849""(cellular detoxification of cadmium ion)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:1903232""(melanosome assembly)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032410|interpro:IPR036640|interpro:IPR039421|mint:Q9NP58|rcsb pdb:3NH6|rcsb pdb:3NH9|rcsb pdb:3NHA|rcsb pdb:3NHB|rcsb pdb:7D7N|rcsb pdb:7D7R|rcsb pdb:7DNY|rcsb pdb:7DNZ|rcsb pdb:7EKL|rcsb pdb:7EKM|rcsb pdb:8FWK|rcsb pdb:8K7B|rcsb pdb:8K7C|rcsb pdb:8YR3|rcsb pdb:8YR4|reactome:R-HSA-1369007|reactome:R-HSA-5683371|refseq:NP_005680.1|efo:""Orphanet:241""|efo:""Orphanet:90044""|efo:""Orphanet:98938""|efo:""Orphanet:98942""|efo:""Orphanet:98943""|efo:""Orphanet:98944""|efo:""Orphanet:98945""|efo:""Orphanet:98946""|efo:""Orphanet:98947"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:3Zyw4d16oU1oT0eiAcOds3s1ZVQ9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q13423	intact:EBI-10760263	intact:EBI-1391318|uniprotkb:Q16796|uniprotkb:Q2TB60|uniprotkb:Q8N3V4|ensembl:ENSP00000264663.5|ensembl:ENSP00000343873.4|ensembl:ENSP00000499249.1|ensembl:ENSP00000499281.1|ensembl:ENSP00000499494.1|ensembl:ENSP00000499527.1|ensembl:ENSP00000499611.1|ensembl:ENSP00000499639.1|intact:EBI-21355735	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:nntm_human(display_long)|uniprotkb:NNT(gene name)|psi-mi:NNT(display_short)|uniprotkb:Nicotinamide nucleotide transhydrogenase(gene name synonym)|uniprotkb:Pyridine nucleotide transhydrogenase(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR10160(orthology-group)|efo:""Orphanet:361""|ensembl:ENSG00000112992.18(gene)|ensembl:ENST00000264663.9(transcript)|ensembl:ENST00000344920.9(transcript)|ensembl:ENST00000653251.1(transcript)|ensembl:ENST00000656666.1(transcript)|ensembl:ENST00000662525.1(transcript)|ensembl:ENST00000669601.1(transcript)|ensembl:ENST00000670904.1(transcript)|ensembl:ENST00000671668.1(transcript)|go:""GO:0003957""(""NAD(P)+ transhydrogenase (Si-specific) activity"")|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006740""(NADPH regeneration)|go:""GO:0008750""(""proton-translocating NAD(P)+ transhydrogenase activity"")|go:""GO:0010918""(positive regulation of mitochondrial membrane potential)|go:""GO:0016020""(membrane)|go:""GO:0032364""(intracellular oxygen homeostasis)|go:""GO:0033273""(response to vitamin)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0098803""(respiratory chain complex)|go:""GO:0098869""(cellular oxidant detoxification)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903285""(positive regulation of hydrogen peroxide catabolic process)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|interpro:IPR024605|interpro:IPR026255|interpro:IPR029035|interpro:IPR034300|interpro:IPR036291|mint:Q13423|rcsb pdb:1DJL|rcsb pdb:1PT9|rcsb pdb:1U31|reactome:R-HSA-71403|refseq:NP_036475.3|refseq:NP_892022.2|refseq:XP_005248331.1|refseq:XP_011512303.1|refseq:XP_016864782.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:iDKBuEy/JvV9q3s4/aHuu58+Gyk9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P31040	intact:EBI-10760263	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q8IW48|uniprotkb:Q59GW8|uniprotkb:A8K5J6|ensembl:ENSP00000264932.6	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)|uniprotkb:Malate dehydrogenase [quinone] flavoprotein subunit(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000073578.18(gene)|ensembl:ENST00000264932.11(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006105""(succinate metabolic process)|go:""GO:0006121""(mitochondrial electron transport, succinate to ubiquinone)|go:""GO:0007399""(nervous system development)|go:""GO:0008177""(""succinate dehydrogenase (quinone) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045273""(""respiratory chain complex II (succinate dehydrogenase)"")|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR030664|interpro:IPR036188|interpro:IPR037099|mint:P31040|rcsb pdb:6VAX|rcsb pdb:8DYD|rcsb pdb:8DYE|rcsb pdb:8GS8|reactome:R-HSA-611105|reactome:R-HSA-71403|reactome:R-HSA-9854311|refseq:NP_001281261.1|refseq:NP_004159.2|efo:""Orphanet:154""|efo:""Orphanet:29072""|efo:""Orphanet:3208""|efo:""Orphanet:44890""|dip:DIP-45851N|panther:PTHR11632(orthology-group)|ensembl:ENSP00000264932.6|ensembl:ENST00000510361.5|ensembl:ENSP00000427703.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9BVC6	intact:EBI-10760263	intact:EBI-1057733|ensembl:ENSP00000227525.3|ensembl:ENSP00000443990.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:tm109_human(display_long)|uniprotkb:TMEM109(gene name)|psi-mi:TMEM109(display_short)|uniprotkb:Mitsugumin-23(gene name synonym)|uniprotkb:Transmembrane protein 109(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_076997.1|ensembl:ENSG00000110108.11(gene)|ensembl:ENST00000227525.8(transcript)|ensembl:ENST00000536171.1(transcript)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0022843""(voltage-gated monoatomic cation channel activity)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0034702""(monoatomic ion channel complex)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071480""(cellular response to gamma radiation)|interpro:IPR039492|mint:Q9BVC6|panther:PTHR14550(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:KsibbFWmzuiZPpo4GqJikbMMaMQ9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P16070	intact:EBI-10760263	intact:EBI-490245|ensembl:ENSP00000398632.2|uniprotkb:P22511|uniprotkb:Q04858|uniprotkb:Q13419|uniprotkb:Q13957|uniprotkb:Q13958|uniprotkb:Q13959|uniprotkb:Q13960|uniprotkb:Q13961|uniprotkb:Q13967|uniprotkb:Q13968|uniprotkb:Q13980|uniprotkb:Q15861|uniprotkb:Q16064|uniprotkb:Q16065|uniprotkb:Q16066|uniprotkb:Q16208|uniprotkb:Q16522|uniprotkb:Q86T72|uniprotkb:Q86Z27|uniprotkb:Q8N694|uniprotkb:Q92493|uniprotkb:Q96J24|uniprotkb:Q9UJ36|uniprotkb:Q9H5A5|uniprotkb:A5YRN9|uniprotkb:Q9UC28|uniprotkb:Q9UC29|uniprotkb:Q9UC30|uniprotkb:Q9UCB0|uniprotkb:D3DR12|uniprotkb:D3DR13|uniprotkb:B6EAT9|uniprotkb:O95370	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:cd44_human(display_long)|uniprotkb:Epican(gene name synonym)|uniprotkb:CDw44(gene name synonym)|uniprotkb:Phagocytic glycoprotein I(gene name synonym)|uniprotkb:Extracellular matrix receptor III(gene name synonym)|uniprotkb:HUTCH-I(gene name synonym)|uniprotkb:Phagocytic glycoprotein 1(gene name synonym)|uniprotkb:GP90 lymphocyte homing/adhesion receptor(gene name synonym)|uniprotkb:Hermes antigen(gene name synonym)|uniprotkb:Hyaluronate receptor(gene name synonym)|uniprotkb:Heparan sulfate proteoglycan(gene name synonym)|uniprotkb:CD44(gene name)|psi-mi:CD44(display_short)|uniprotkb:LHR(gene name synonym)|uniprotkb:MDU2(gene name synonym)|uniprotkb:MDU3(gene name synonym)|uniprotkb:MIC4(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0009986""(cell surface)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|ensembl:ENSG00000026508.21(gene)|ensembl:ENST00000428726.8(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005540""(hyaluronic acid binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005925""(focal adhesion)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0016477""(cell migration)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042995""(cell projection)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0051216""(cartilage development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070487""(monocyte aggregation)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:1900625""(positive regulation of monocyte aggregation)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000392""(regulation of lamellipodium morphogenesis)|interpro:IPR000538(Link)|interpro:IPR001231(CD44 antigen)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR043210|mint:P16070|rcsb pdb:1POZ|rcsb pdb:1UUH|rcsb pdb:2I83|rcsb pdb:4PZ3|rcsb pdb:4PZ4|rcsb pdb:6TXS|reactome:R-HSA-1474228|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2160916|reactome:R-HSA-6798695|reactome:R-HSA-877300|refseq:NP_000601.3|refseq:NP_001001389.1|refseq:NP_001001390.1|refseq:NP_001001391.1|refseq:NP_001001392.1|refseq:NP_001189484.1|refseq:NP_001189485.1|refseq:NP_001189486.1|refseq:XP_011518790.1|dip:DIP-1121N|panther:PTHR10225(orthology-group)|ensembl:ENST00000263398.11|ensembl:ENSP00000263398.6|ensembl:ENST00000278386.10|ensembl:ENSP00000278386.6|ensembl:ENST00000352818.8|ensembl:ENSP00000309732.6|ensembl:ENST00000415148.6|ensembl:ENSP00000389830.2|ensembl:ENSP00000398632.2|ensembl:ENST00000433892.6|ensembl:ENSP00000392331.2|ensembl:ENST00000434472.6|ensembl:ENSP00000404447.2"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:QOb28rF7/ryqfz/ylJFTyL3aoAc9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q01650	intact:EBI-10760263	intact:EBI-6138761|uniprotkb:Q8IV97|uniprotkb:Q9UBN8|uniprotkb:Q9UP15|uniprotkb:Q9UQC0|ensembl:ENSP00000261622.4	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:lat1_human(display_long)|uniprotkb:SLC7A5(gene name)|psi-mi:SLC7A5(display_short)|uniprotkb:CD98LC(gene name synonym)|uniprotkb:LAT1(gene name synonym)|uniprotkb:MPE16(gene name synonym)|uniprotkb:4F2 light chain(gene name synonym)|uniprotkb:CD98 light chain(gene name synonym)|uniprotkb:Integral membrane protein E16(gene name synonym)|uniprotkb:L-type amino acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 7 member 5(gene name synonym)|uniprotkb:y+ system cationic amino acid transporter(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_003477.4|ensembl:ENSG00000103257.10(gene)|ensembl:ENST00000261622.5(transcript)|go:""GO:0002720""(positive regulation of cytokine production involved in immune response)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015196""(L-tryptophan transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015349""(thyroid hormone transmembrane transporter activity)|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032328""(alanine transport)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042908""(xenobiotic transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0089718""(amino acid import across plasma membrane)|go:""GO:0097421""(liver regeneration)|go:""GO:0098591""(external side of apical plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903577""(cellular response to L-arginine)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904556""(L-tryptophan transmembrane transport)|go:""GO:1905460""(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:""GO:1905534""(positive regulation of L-leucine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004760(L-type amino acid transporter)|interpro:IPR050598|mint:Q01650|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|rcsb pdb:8XPU|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-71240|panther:PTHR11785(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:GrXTCUhrHMNCnvscgx1ink2opoU9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P07099	intact:EBI-10760263	intact:EBI-6138796|uniprotkb:B2R8N0|uniprotkb:Q5VTJ6|uniprotkb:Q9NP75|uniprotkb:Q9NPE7|uniprotkb:Q9NQU6|uniprotkb:Q9NQU7|uniprotkb:Q9NQU8|uniprotkb:Q9NQU9|uniprotkb:Q9NQV0|uniprotkb:Q9NQV1|uniprotkb:Q9NQV2|ensembl:ENSP00000272167.5|ensembl:ENSP00000355802.4|ensembl:ENSP00000480004.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:hyep_human(display_long)|uniprotkb:EPHX1(gene name)|psi-mi:EPHX1(display_short)|uniprotkb:EPHX(gene name synonym)|uniprotkb:EPOX(gene name synonym)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000143819.13(gene)|ensembl:ENST00000272167.10(transcript)|ensembl:ENST00000366837.5(transcript)|ensembl:ENST00000614058.4(transcript)|go:""GO:0004301""(epoxide hydrolase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0009636""(response to toxic substance)|go:""GO:0019369""(arachidonate metabolic process)|go:""GO:0033961""(cis-stilbene-oxide hydrolase activity)|go:""GO:0097176""(epoxide metabolic process)|go:""GO:0120253""(hydrocarbon catabolic process)|go:""GO:1903165""(response to polycyclic arene)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|mint:P07099|reactome:R-HSA-211945|refseq:NP_000111.1|refseq:NP_001129490.1|refseq:NP_001278092.1|efo:""Orphanet:238475""|panther:PTHR21661(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:VtIgDuQpQQbLSdFLOBBx9yHHiBE9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9Y4W6	intact:EBI-10760263	intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym)|uniprotkb:AFG3-like protein 2(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000141385.12(gene)|ensembl:ENST00000269143.8(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005745""(m-AAA complex)|go:""GO:0006508""(proteolysis)|go:""GO:0007409""(axonogenesis)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0008053""(mitochondrial fusion)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016485""(protein processing)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0021675""(nerve development)|go:""GO:0030163""(protein catabolic process)|go:""GO:0033619""(membrane protein proteolysis)|go:""GO:0034982""(mitochondrial protein processing)|go:""GO:0036444""(calcium import into the mitochondrion)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042407""(cristae formation)|go:""GO:0042552""(myelination)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:0051604""(protein maturation)|go:""GO:0055001""(muscle cell development)|go:""GO:0060013""(righting reflex)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0072753""(cellular response to glutathione)|go:""GO:0110097""(regulation of calcium import into the mitochondrion)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:0141164""(mitochondrial protein quality control)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|interpro:IPR050928|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664|reactome:R-HSA-9837999|refseq:NP_006787.2|efo:""Orphanet:101109""|efo:""Orphanet:313772""|panther:PTHR43655(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P11279	intact:EBI-10760263	intact:EBI-2805407|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40|ensembl:ENSP00000333298.4|uniprotkb:B4DWL3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_005552.3|ensembl:ENSG00000185896.11(gene)|ensembl:ENST00000332556.5(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0001618""(virus receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0044754""(autolysosome)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0061474""(phagolysosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072594""(establishment of protein localization to organelle)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0140507""(granzyme-mediated programmed cell death signaling pathway)|go:""GO:1902513""(regulation of organelle transport along microtubule)|interpro:IPR002000(""Lysosome-associated membrane glycoprotein (Lamp)/CD68"")|interpro:IPR018134|interpro:IPR048524|interpro:IPR048528|mint:P11279|rcsb pdb:8ATH|rcsb pdb:8FY5|rcsb pdb:8FYF|reactome:R-HSA-6798695|dip:DIP-44670N|panther:PTHR11506(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P06576	intact:EBI-10760263	intact:EBI-356231|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803|ensembl:ENSP00000262030.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001677.2|interpro:IPR036121|ensembl:ENSG00000110955.9(gene)|ensembl:ENST00000262030.8(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005886""(plasma membrane)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0006933""(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:""GO:0009986""(cell surface)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0043532""(angiostatin binding)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0045267""(obsolete proton-transporting ATP synthase, catalytic core)|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0051453""(regulation of intracellular pH)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR050053|interpro:IPR055190|mint:P06576|rcsb pdb:8H9E|rcsb pdb:8H9I|rcsb pdb:8H9L|rcsb pdb:8H9P|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KI3|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|reactome:R-HSA-9837999|panther:PTHR15184(orthology-group)|ensembl:ENSP00000262030.3"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q8TCT9	intact:EBI-10760263	intact:EBI-347472|uniprotkb:Q540H8|uniprotkb:Q5JWP2|uniprotkb:Q5JWP3|uniprotkb:Q5JWP4|uniprotkb:Q5JWP5|uniprotkb:Q7Z4F2|uniprotkb:Q86Y35|uniprotkb:Q95H87|uniprotkb:Q9H110|uniprotkb:Q9H111|uniprotkb:Q15K36|uniprotkb:B2RAY5|uniprotkb:E1P5L3|ensembl:ENSP00000343032.5	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:hm13_human(display_long)|uniprotkb:HM13(gene name)|psi-mi:HM13(display_short)|uniprotkb:H13(gene name synonym)|uniprotkb:PSL3(gene name synonym)|uniprotkb:SPP(gene name synonym)|uniprotkb:Signal peptide peptidase(gene name synonym)|uniprotkb:Presenilin-like protein 3(gene name synonym)|uniprotkb:Intramembrane protease 1(gene name synonym)|uniprotkb:IMP1(gene name synonym)|uniprotkb:MSTP086(orf name)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_110416.1|refseq:NP_848695.1|refseq:NP_848696.1|refseq:NP_848697.1|panther:PTHR12174(orthology-group)|ensembl:ENSG00000101294.20(gene)|ensembl:ENST00000340852.9(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006465""(signal peptide processing)|go:""GO:0008233""(peptidase activity)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0033619""(membrane protein proteolysis)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0036513""(Derlin-1 retrotranslocation complex)|go:""GO:0042500""(aspartic endopeptidase activity, intramembrane cleaving)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:1904211""(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR007369(Peptidase A22B, signal peptide peptidase)|mint:Q8TCT9|reactome:R-HSA-9707587"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:DxNjJDcc+zomfXAj0TEaByKeNqc9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P02786	intact:EBI-10760263	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224.4|ensembl:ENSP00000376197.3|ensembl:ENSP00000513646.1|ensembl:ENSP00000513654.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:476113""|ensembl:ENSG00000072274.14(gene)|ensembl:ENST00000360110.9(transcript)|ensembl:ENST00000392396.7(transcript)|ensembl:ENST00000698280.1(transcript)|ensembl:ENST00000698291.1(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004998""(transferrin receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010039""(response to iron ion)|go:""GO:0010042""(response to manganese ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010637""(negative regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033572""(transferrin transport)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0046688""(response to copper ion)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0072562""(blood microparticle)|go:""GO:0098944""(postsynaptic recycling endosome membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|interpro:IPR046450|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|rcsb pdb:7ZQS|rcsb pdb:8P0Z|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9725554|refseq:NP_001121620.1|refseq:NP_001300894.1|refseq:NP_001300895.1|refseq:NP_003225.2|dip:DIP-2736N|panther:PTHR10404(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P25705	intact:EBI-10760263	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|ensembl:ENSP00000282050.2|ensembl:ENSP00000381736.5|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|intact:EBI-11032691	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:254913""|ensembl:ENSG00000152234.16(gene)|ensembl:ENST00000282050.6(transcript)|ensembl:ENST00000398752.11(transcript)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0002020""(protease binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0009986""(cell surface)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0043531""(ADP binding)|go:""GO:0043532""(angiostatin binding)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0045121""(membrane raft)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0045471""(response to ethanol)|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0071732""(cellular response to nitric oxide)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|rcsb pdb:8H9E|rcsb pdb:8H9I|rcsb pdb:8H9L|rcsb pdb:8H9P|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KI3|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613|reactome:R-HSA-9837999|refseq:NP_001001935.1|refseq:NP_001001937.1|refseq:NP_001244263.1|refseq:NP_001244264.1|refseq:NP_004037.1|dip:DIP-32871N|panther:PTHR48082(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P39656	intact:EBI-10760263	intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457.3|uniprotkb:B4DJE3|uniprotkb:B4DLI2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000244038.11(gene)|ensembl:ENST00000415136.6(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0034097""(response to cytokine)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042110""(T cell activation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548|refseq:NP_005207.2|efo:""Orphanet:300536""|panther:PTHR10830(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O00116	intact:EBI-10760263	intact:EBI-2838732|uniprotkb:A5D8U9|uniprotkb:Q2TU35|ensembl:ENSP00000264167.4	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:adas_human(display_long)|uniprotkb:AGPS(gene name)|psi-mi:AGPS(display_short)|uniprotkb:Aging-associated gene 5 protein(gene name synonym)|uniprotkb:Alkylglycerone-phosphate synthase(gene name synonym)|uniprotkb:AAG5(orf name)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000018510.18(gene)|ensembl:ENST00000264167.11(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0008609""(alkylglycerone-phosphate synthase activity)|go:""GO:0008610""(lipid biosynthetic process)|go:""GO:0008611""(ether lipid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0071949""(FAD binding)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR025650|interpro:IPR036318|mint:O00116|reactome:R-HSA-75896|reactome:R-HSA-9033241|reactome:R-HSA-9033500|refseq:NP_003650.1|efo:""Orphanet:309803""|panther:PTHR46568(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:P8f6+j/f+WID0lFZnLIvVN5OSzM9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P27824	intact:EBI-10760263	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000247461.4|ensembl:ENSP00000391646.2|ensembl:ENSP00000421434.2|ensembl:ENSP00000421813.2|ensembl:ENSP00000424063.1|ensembl:ENSP00000424745.2|ensembl:ENSP00000491760.1|ensembl:ENSP00000492372.1|ensembl:ENSP00000492868.1|ensembl:ENSP00000505013.1|ensembl:ENSP00000505202.1|ensembl:ENSP00000505526.1|ensembl:ENSP00000505960.1|ensembl:ENSP00000506003.1|ensembl:ENSP00000506021.1|ensembl:ENSP00000506061.1|ensembl:ENSP00000506078.1|ensembl:ENSP00000506509.1|ensembl:ENSP00000506568.1|ensembl:ENSP00000506583.1|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|ensembl:ENSG00000127022.16(gene)|ensembl:ENSG00000283777.2(gene)|ensembl:ENST00000247461.9(transcript)|ensembl:ENST00000452673.6(transcript)|ensembl:ENST00000502296.6(transcript)|ensembl:ENST00000504734.5(transcript)|ensembl:ENST00000509563.2(transcript)|ensembl:ENST00000513246.6(transcript)|ensembl:ENST00000638425.1(transcript)|ensembl:ENST00000638706.2(transcript)|ensembl:ENST00000639938.1(transcript)|ensembl:ENST00000680013.1(transcript)|ensembl:ENST00000680042.1(transcript)|ensembl:ENST00000680092.1(transcript)|ensembl:ENST00000680618.1(transcript)|ensembl:ENST00000681072.1(transcript)|ensembl:ENST00000681168.1(transcript)|ensembl:ENST00000681476.1(transcript)|ensembl:ENST00000681674.1(transcript)|ensembl:ENST00000681712.1(transcript)|ensembl:ENST00000681733.1(transcript)|ensembl:ENST00000681903.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006457""(protein folding)|go:""GO:0009306""(protein secretion)|go:""GO:0016020""(membrane)|go:""GO:0019082""(viral protein processing)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0036503""(ERAD pathway)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0044322""(endoplasmic reticulum quality control compartment)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098793""(presynapse)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|dip:DIP-457N|panther:PTHR11073(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P16615	intact:EBI-10760263	intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	"psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:""Endoplasmic reticulum class 1/2 Ca(2+) ATPase""(gene name synonym)"	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR42861(orthology-group)|efo:""Orphanet:218""|efo:""Orphanet:79151""|ensembl:ENSG00000174437.18(gene)|ensembl:ENST00000539276.7(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0005388""(P-type calcium transporter activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006984""(ER-nucleus signaling pathway)|go:""GO:0007155""(cell adhesion)|go:""GO:0008544""(epidermis development)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0010882""(regulation of cardiac muscle contraction by calcium ion signaling)|go:""GO:0014801""(longitudinal sarcoplasmic reticulum)|go:""GO:0014883""(transition between fast and slow fiber)|go:""GO:0014898""(cardiac muscle hypertrophy in response to stress)|go:""GO:0016020""(membrane)|go:""GO:0016240""(autophagosome membrane docking)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0032470""(positive regulation of endoplasmic reticulum calcium ion concentration)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0033292""(T-tubule organization)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0070296""(sarcoplasmic reticulum calcium ion transport)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0086036""(regulation of cardiac muscle cell membrane potential)|go:""GO:0086039""(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:""GO:0090534""(calcium ion-transporting ATPase complex)|go:""GO:0097470""(ribbon synapse)|go:""GO:0098909""(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:""GO:0106222""(lncRNA binding)|go:""GO:0140056""(organelle localization by membrane tethering)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1903233""(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:""GO:1903515""(calcium ion transport from cytosol to endoplasmic reticulum)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1990036""(calcium ion import into sarcoplasmic reticulum)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|rcsb pdb:7E7S|rcsb pdb:7W7T|rcsb pdb:7W7U|rcsb pdb:7W7V|rcsb pdb:7W7W|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_005253945.1|refseq:XP_011536704.1|dip:DIP-33868N"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61026	intact:EBI-10760263	intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710.4	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_057215.3|ensembl:ENSG00000084733.11(gene)|ensembl:ENST00000264710.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0007409""(axonogenesis)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0019003""(GDP binding)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0031489""(myosin V binding)|go:""GO:0032593""(insulin-responsive compartment)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045200""(establishment of neuroblast polarity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070382""(exocytic vesicle)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0097051""(establishment of protein localization to endoplasmic reticulum membrane)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0099503""(secretory vesicle)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:P61026|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9UHG3	intact:EBI-10760263	intact:EBI-2908417|uniprotkb:B2RB14|uniprotkb:O94982|uniprotkb:Q8N4N5|uniprotkb:Q96QM8|uniprotkb:B7Z9P8|ensembl:ENSP00000387654.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:pcyox_human(display_long)|uniprotkb:PCYOX1(gene name)|psi-mi:PCYOX1(display_short)|uniprotkb:KIAA0908(gene name synonym)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Prenylcysteine lyase(gene name synonym)|uniprotkb:UNQ597/PRO1183(orf name)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_057381.3|ensembl:ENSG00000116005.12(gene)|ensembl:ENST00000433351.7(transcript)|go:""GO:0001735""(prenylcysteine oxidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0030327""(prenylated protein catabolic process)|go:""GO:0030328""(prenylcysteine catabolic process)|go:""GO:0034361""(very-low-density lipoprotein particle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071949""(FAD binding)|go:""GO:0102149""(farnesylcysteine lyase activity)|interpro:IPR010795(Prenylcysteine lyase)|interpro:IPR017046(Prenylcysteine oxidase)|interpro:IPR036188|mint:Q9UHG3|panther:PTHR15944(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:E7WR6qZZuoGqmWQ+CX6PeZX/yEw9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P51149	intact:EBI-10760263	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062.3|ensembl:ENSP00000501618.1|ensembl:ENSP00000502000.1|ensembl:ENSP00000502088.1|ensembl:ENSP00000502486.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000075785.14(gene)|ensembl:ENST00000265062.8(transcript)|ensembl:ENST00000674589.1(transcript)|ensembl:ENST00000675342.1(transcript)|ensembl:ENST00000675497.1(transcript)|ensembl:ENST00000676214.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0019003""(GDP binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0036466""(synaptic vesicle recycling via endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045453""(bone resorption)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048524""(positive regulation of viral process)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090383""(phagosome acidification)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0097208""(alveolar lamellar body)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:1903542""(negative regulation of exosomal secretion)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1905366""(negative regulation of intralumenal vesicle formation)|go:""GO:1905394""(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:3LAW|rcsb pdb:6IYB|rcsb pdb:6WCW|rcsb pdb:7F6J|rcsb pdb:8KB8|rcsb pdb:8ZQ3|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|refseq:NP_004628.4|efo:""Orphanet:99936""|dip:DIP-39879N|panther:PTHR47981(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9H845	intact:EBI-10760263	intact:EBI-2510719|uniprotkb:Q8WXX3|uniprotkb:D3DNB8|ensembl:ENSP00000312618.7|ensembl:ENSP00000506340.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"dip:DIP-53699N|efo:""Orphanet:99901""|ensembl:ENSG00000177646.20(gene)|ensembl:ENST00000308982.12(transcript)|ensembl:ENST00000681583.1(transcript)|go:""GO:0001676""(long-chain fatty acid metabolic process)|go:""GO:0003995""(acyl-CoA dehydrogenase activity)|go:""GO:0004466""(long-chain fatty acyl-CoA dehydrogenase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0030425""(dendrite)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032981""(mitochondrial respiratory chain complex I assembly)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0051791""(medium-chain fatty acid metabolic process)|go:""GO:0070991""(medium-chain fatty acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|interpro:IPR046373|interpro:IPR049448|mint:Q9H845|rcsb pdb:8PHE|rcsb pdb:8PHF|reactome:R-HSA-6799198|refseq:NP_054768.2|panther:PTHR43884(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q03519	intact:EBI-10760263	intact:EBI-780781|uniprotkb:Q9UQ83|uniprotkb:O95410|uniprotkb:B0V2J8|uniprotkb:Q53FI6|uniprotkb:Q5HY71|uniprotkb:Q96PT8|ensembl:ENSP00000364032.3|ensembl:ENSP00000372599.4|ensembl:ENSP00000372726.4|ensembl:ENSP00000390013.2|ensembl:ENSP00000394101.2|ensembl:ENSP00000513722.1|ensembl:ENSP00000513733.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:tap2_human(display_long)|uniprotkb:ATP-binding cassette sub-family B member 3(gene name synonym)|uniprotkb:Peptide transporter TAP2(gene name synonym)|uniprotkb:Peptide supply factor 2(gene name synonym)|uniprotkb:Peptide transporter PSF2(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 2(gene name synonym)|uniprotkb:TAP2(gene name)|psi-mi:TAP2(display_short)|uniprotkb:ABCB3(gene name synonym)|uniprotkb:PSF2(gene name synonym)|uniprotkb:RING11(gene name synonym)|uniprotkb:Y1(gene name synonym)|uniprotkb:Really interesting new gene 11 protein(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"dip:DIP-322N|ensembl:ENSG00000204267.19(gene)|ensembl:ENSG00000206235.8(gene)|ensembl:ENSG00000206299.8(gene)|ensembl:ENSG00000228582.9(gene)|ensembl:ENSG00000237599.9(gene)|ensembl:ENST00000374897.4(transcript)|ensembl:ENST00000383118.8(transcript)|ensembl:ENST00000383239.8(transcript)|ensembl:ENST00000419142.6(transcript)|ensembl:ENST00000443713.6(transcript)|ensembl:ENST00000698440.1(transcript)|ensembl:ENST00000698448.1(transcript)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002485""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:""GO:0002489""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent)|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0015031""(protein transport)|go:""GO:0015433""(ABC-type peptide antigen transporter activity)|go:""GO:0015440""(ABC-type peptide transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0023029""(MHC class Ib protein binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0042825""(TAP complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0046967""(cytosol to endoplasmic reticulum transport)|go:""GO:0046968""(peptide antigen transport)|go:""GO:0046978""(TAP1 binding)|go:""GO:0046980""(tapasin binding)|go:""GO:0055085""(transmembrane transport)|go:""GO:1904680""(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03519|rcsb pdb:5U1D|rcsb pdb:8T46|rcsb pdb:8T4E|rcsb pdb:8T4F|rcsb pdb:8T4G|rcsb pdb:8T4H|rcsb pdb:8T4I|rcsb pdb:8T4J|reactome:R-HSA-1236974|reactome:R-HSA-983170|refseq:NP_000535.3|refseq:NP_001276972.1|refseq:NP_061313.2|efo:""Orphanet:34592""|panther:PTHR24221(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:w7pDqjoSODoB8qMag1ycxcapvQ09606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q96KA5	intact:EBI-10760263	intact:EBI-3216282|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1|ensembl:ENSP00000313854.5|ensembl:ENSP00000480372.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:clp1l_human(display_long)|uniprotkb:Cleft lip and palate transmembrane protein 1-like protein(gene name synonym)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_110409.2|ensembl:ENSG00000049656.14(gene)|ensembl:ENSG00000274811.3(gene)|ensembl:ENST00000320895.10(transcript)|ensembl:ENST00000620010.3(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0017128""(phospholipid scramblase activity)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|mint:Q96KA5|panther:PTHR21347(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9HDC9	intact:EBI-10760263	intact:EBI-723950|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1|ensembl:ENSP00000217456.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_065392.1|refseq:XP_005260820.1|ensembl:ENSG00000101474.12(gene)|ensembl:ENST00000217456.3(transcript)|go:""GO:0004064""(arylesterase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016844""(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|panther:PTHR10426(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P05023	intact:EBI-10760263	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|ensembl:ENSP00000295598.5|intact:EBI-10963133	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR43294(orthology-group)|ensembl:ENSG00000163399.16(gene)|ensembl:ENST00000295598.10(transcript)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0005391""(""P-type sodium:potassium-exchanging transporter activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0007231""(osmosensory signaling pathway)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016791""(phosphatase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030315""(T-tubule)|go:""GO:0030424""(axon)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031090""(organelle membrane)|go:""GO:0031402""(sodium ion binding)|go:""GO:0031947""(negative regulation of glucocorticoid biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0045823""(positive regulation of heart contraction)|go:""GO:0045989""(positive regulation of striated muscle contraction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060342""(photoreceptor inner segment membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086009""(membrane repolarization)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903416""(response to glycoside)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990239""(steroid hormone binding)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|interpro:IPR050510|mint:P05023|rcsb pdb:7E1Z|rcsb pdb:7E20|rcsb pdb:7E21|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|efo:""Orphanet:521414""|efo:""Orphanet:564178"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P36542	intact:EBI-10760263	intact:EBI-711768|ensembl:ENSP00000349142.7|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000165629.20(gene)|ensembl:ENST00000356708.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016020""(membrane)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|rcsb pdb:8H9E|rcsb pdb:8H9F|rcsb pdb:8H9I|rcsb pdb:8H9J|rcsb pdb:8H9L|rcsb pdb:8H9M|rcsb pdb:8H9P|rcsb pdb:8H9Q|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|reactome:R-HSA-9837999|refseq:NP_001001973.1|refseq:NP_005165.1|panther:PTHR11693(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q99805	intact:EBI-10760263	intact:EBI-2852254|uniprotkb:Q2TAY5|uniprotkb:A8K399|ensembl:ENSP00000365567.3|ensembl:ENSP00000493515.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:tm9s2_human(display_long)|uniprotkb:TM9SF2(gene name)|psi-mi:TM9SF2(display_short)|uniprotkb:p76(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_004791.1|ensembl:ENSG00000125304.10(gene)|ensembl:ENST00000376387.5(transcript)|ensembl:ENST00000642475.1(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005886""(plasma membrane)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0006688""(glycosphingolipid biosynthetic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0010908""(regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|interpro:IPR004240(""Nonaspanin (TM9SF)"")|mint:Q99805|panther:PTHR10766(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:qg5QSnzX8+4H0Nfab7Ci9n9igc09606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P46977	intact:EBI-10760263	intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472.3|ensembl:ENSP00000436962.1|ensembl:ENSP00000497336.1|uniprotkb:B4DJ24|uniprotkb:E9PNQ1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:370921""|ensembl:ENSG00000134910.14(gene)|ensembl:ENST00000392708.9(transcript)|ensembl:ENST00000529196.5(transcript)|ensembl:ENST00000649491.1(transcript)|go:""GO:0004579""(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0043686""(co-translational protein modification)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0046872""(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|interpro:IPR048307|interpro:IPR054479|mint:P46977|rcsb pdb:6S7O|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_001265432.1|refseq:NP_001265433.1|refseq:NP_689926.1|refseq:XP_011541109.1|panther:PTHR13872(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O60313	intact:EBI-10760263	intact:EBI-1054131|uniprotkb:D3DNW4|uniprotkb:E5KLJ5|uniprotkb:E5KLJ6|uniprotkb:E5KLJ7|uniprotkb:E5KLK1|uniprotkb:E5KLK2|ensembl:ENSP00000354429.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:opa1_human(display_long)|uniprotkb:Optic atrophy protein 1(gene name synonym)|uniprotkb:OPA1(gene name)|psi-mi:OPA1(display_short)|uniprotkb:KIAA0567(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:1215""|efo:""Orphanet:98673""|efo:""Orphanet:1239""|ensembl:ENSG00000198836.11(gene)|ensembl:ENST00000361828.7(transcript)|go:""GO:0000002""(mitochondrial genome maintenance)|go:""GO:0000266""(mitochondrial fission)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006915""(apoptotic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007007""(inner mitochondrial membrane organization)|go:""GO:0007601""(visual perception)|go:""GO:0008017""(microtubule binding)|go:""GO:0008053""(mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0019896""(axonal transport of mitochondrion)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030425""(dendrite)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0042407""(cristae formation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046039""(GTP metabolic process)|go:""GO:0051259""(protein complex oligomerization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0097749""(membrane tubulation)|go:""GO:0140523""(GTPase-dependent fusogenic activity)|go:""GO:0180020""(membrane bending activity)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990627""(mitochondrial inner membrane fusion)|go:""GO:2000330""(positive regulation of T-helper 17 cell lineage commitment)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR045063|interpro:IPR045817|mint:O60313|rcsb pdb:6JTG|rcsb pdb:8CT1|rcsb pdb:8CT9|rcsb pdb:8EEW|rcsb pdb:8EF7|rcsb pdb:8EFF|rcsb pdb:8EFR|rcsb pdb:8EFS|rcsb pdb:8EFT|reactome:R-HSA-169911|reactome:R-HSA-9837999|refseq:NP_056375.2|refseq:NP_570844.1|refseq:NP_570846.1|refseq:NP_570847.2|refseq:NP_570849.2|refseq:NP_570850.2|panther:PTHR11566(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:1VmujqR2PEGFIgK9mV+8g57wVb89606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61106	intact:EBI-10760263	intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946.4|ensembl:ENSP00000515613.1|ensembl:ENSP00000515614.1|intact:EBI-21352994	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_057406.2|ensembl:ENSG00000119396.12(gene)|ensembl:ENST00000373840.9(transcript)|ensembl:ENST00000703999.1(transcript)|ensembl:ENST00000704000.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001845""(phagolysosome assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005795""(Golgi stack)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019003""(GDP binding)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0031489""(myosin V binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0042175""(nuclear outer membrane-endoplasmic reticulum membrane network)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090382""(phagosome maturation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|interpro:IPR050209|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9UIQ6	intact:EBI-10760263	intact:EBI-2805360|uniprotkb:O00769|uniprotkb:Q9TNQ2|uniprotkb:Q9TNQ3|uniprotkb:Q9UIQ7|uniprotkb:Q59H76|uniprotkb:Q15145|ensembl:ENSP00000231368.5	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:lcap_human(display_long)|uniprotkb:OTASE(gene name synonym)|uniprotkb:Oxytocinase(gene name synonym)|uniprotkb:Insulin-regulated membrane aminopeptidase(gene name synonym)|uniprotkb:Insulin-responsive aminopeptidase(gene name synonym)|uniprotkb:Placental leucine aminopeptidase(gene name synonym)|uniprotkb:LNPEP(gene name)|psi-mi:LNPEP(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_005566.2|refseq:NP_787116.2|ensembl:ENSG00000113441.16(gene)|ensembl:ENST00000231368.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0002480""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007565""(female pregnancy)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0042277""(peptide binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|interpro:IPR045357|interpro:IPR050344|mint:Q9UIQ6|rcsb pdb:4P8Q|rcsb pdb:4PJ6|rcsb pdb:4Z7I|rcsb pdb:5C97|rcsb pdb:5JHQ|rcsb pdb:5MJ6|rcsb pdb:7ZYF|rcsb pdb:8CGP|rcsb pdb:8CGW|rcsb pdb:8P0I|reactome:R-HSA-1236977|reactome:R-HSA-1445148|reactome:R-HSA-983168|panther:PTHR11533(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:IOU7GW8f6aBYAjIUQXFKbU5Hqkw9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9H3N1	intact:EBI-10760263	intact:EBI-1051115|uniprotkb:Q8N487|uniprotkb:Q8NBN5|uniprotkb:Q9Y4T6|uniprotkb:B2R7A4|ensembl:ENSP00000393316.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:tmx1_human(display_long)|uniprotkb:Transmembrane Trx-related protein(gene name synonym)|uniprotkb:TMX1(gene name)|psi-mi:TMX1(display_short)|uniprotkb:TXNDC1(gene name synonym)|uniprotkb:TMX(gene name synonym)|uniprotkb:TXNDC(gene name synonym)|uniprotkb:PSEC0085(orf name)|uniprotkb:UNQ235/PRO268(orf name)|uniprotkb:Thioredoxin domain-containing protein 1(gene name synonym)|uniprotkb:Protein disulfide-isomerase TMX1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033383|imex:IM-29092-81	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_110382.3|ensembl:ENSG00000139921.13(gene)|ensembl:ENST00000457354.7(transcript)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0010868""(negative regulation of triglyceride biosynthetic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:1904294""(positive regulation of ERAD pathway)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR052454|mint:Q9H3N1|rcsb pdb:1X5E|panther:PTHR46107(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:ZJH5N22Dnrk+SXa3Ysqqfu1md/I9606	intact-crc:B7CB7BE799DEC073|rigid:gVFeC2VkpOlWNQWttv+NQONVkds	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:P22059	intact:EBI-13953897	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033608|imex:IM-29092-83	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	intact-crc:56571EF997B64C72|rigid:c/nJMVdtrXSFV2uHWS1wB+MRphI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q53EL6	intact:EBI-27033646	intact:EBI-935824|uniprotkb:O15501|uniprotkb:Q5VZS6|uniprotkb:Q6PJI5|uniprotkb:Q8TAR5|uniprotkb:Q99834|intact:EBI-2514227|uniprotkb:B2RCV4|uniprotkb:B5ME91|ensembl:ENSP00000280154.7	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:pdcd4_human(display_long)|uniprotkb:PDCD4(gene name)|psi-mi:PDCD4(display_short)|uniprotkb:H731(gene name synonym)|uniprotkb:Nuclear antigen H731-like(gene name synonym)|uniprotkb:Neoplastic transformation inhibitor protein(gene name synonym)|uniprotkb:Protein 197/15a(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033657|imex:IM-29092-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_055271.2|refseq:NP_663314.1|ensembl:ENSG00000150593.18(gene)|ensembl:ENST00000280154.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0009725""(response to hormone)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043279""(response to alkaloid)|go:""GO:0043508""(negative regulation of JUN kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0060940""(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:1900016""(negative regulation of cytokine production involved in inflammatory response)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904761""(negative regulation of myofibroblast differentiation)|go:""GO:1905064""(negative regulation of vascular associated smooth muscle cell differentiation)|go:""GO:1905461""(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:""GO:2000353""(positive regulation of endothelial cell apoptotic process)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039778|mint:Q53EL6|rcsb pdb:2GGF|rcsb pdb:2KZT|rcsb pdb:2RG8|rcsb pdb:2ZU6|rcsb pdb:3EIJ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:9BKD|rcsb pdb:9BLN|reactome:R-HSA-8950505|dip:DIP-29756N|ensembl:ENSP00000280154.7|ensembl:ENST00000393104.6|ensembl:ENSP00000376816.2|panther:PTHR12626(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/27	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:kkqDk2CCFvHpSCKNDzV4wqSm1HE9606	intact-crc:E40CC8AFE16FA717|rigid:WUrLl39vyMa1FPIxfrMmmCgdvTc	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:P63220	intact:EBI-27033646	intact:EBI-714051|uniprotkb:P35265|ensembl:ENSP00000345957.3	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:rs21_human(display_long)|uniprotkb:RPS21(gene name)|psi-mi:RPS21(display_short)|uniprotkb:40S ribosomal protein S21(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033657|imex:IM-29092-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_001015.1|ensembl:ENSG00000171858.18(gene)|ensembl:ENST00000343986.9(transcript)|go:""GO:0000447""(""endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0000461""(""endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0015935""(small ribosomal subunit)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0045202""(synapse)|interpro:IPR001931(Ribosomal protein S21e)|interpro:IPR018279|interpro:IPR038579|mint:P63220|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7QVP|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7WTV|rcsb pdb:7WTW|rcsb pdb:7WTX|rcsb pdb:7WTZ|rcsb pdb:7WU0|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9735869|reactome:R-HSA-9754678|reactome:R-HSA-975956|reactome:R-HSA-975957|panther:PTHR10442(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/27	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:3gi91+fAL7ogzcoJlVEaN4D+87A9606	intact-crc:E40CC8AFE16FA717|rigid:WUrLl39vyMa1FPIxfrMmmCgdvTc	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q15582	intact:EBI-27033646	intact:EBI-10236573|uniprotkb:D3DQB1|uniprotkb:O43218|uniprotkb:O43217|uniprotkb:O14476|uniprotkb:O14472|uniprotkb:O43216|uniprotkb:O43219|uniprotkb:Q53XM1|uniprotkb:O14471|ensembl:ENSP00000416330.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:bgh3_human(display_long)|uniprotkb:TGFBI(gene name)|psi-mi:TGFBI(display_short)|uniprotkb:BIGH3(gene name synonym)|uniprotkb:Kerato-epithelin(gene name synonym)|uniprotkb:RGD-containing collagen-associated protein(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033657|imex:IM-29092-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"panther:PTHR10900(orthology-group)|ensembl:ENSG00000120708.17(gene)|ensembl:ENST00000442011.7(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007601""(visual perception)|go:""GO:0008283""(cell population proliferation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0031012""(extracellular matrix)|go:""GO:0042802""(identical protein binding)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000782(Beta-Ig-H3/fasciclin)|interpro:IPR011489(EMI)|interpro:IPR016666(TGF beta-induced protein bIGH3/osteoblast-specific factor 2)|interpro:IPR036378|interpro:IPR050904|mint:Q15582|rcsb pdb:1X3B|rcsb pdb:2LTB|rcsb pdb:2LTC|rcsb pdb:2VXP|rcsb pdb:5NV6|rcsb pdb:7AS7|rcsb pdb:7ASC|rcsb pdb:7ASG|rcsb pdb:8HGA|rcsb pdb:8HIA|reactome:R-HSA-977225|refseq:NP_000349.1|efo:""Orphanet:98956""|efo:""Orphanet:98960""|efo:""Orphanet:98961""|efo:""Orphanet:98962""|efo:""Orphanet:98963""|efo:""Orphanet:98964"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/27	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:86Kh2QpWO6GxkrQsjbtqcBrKs4M9606	intact-crc:E40CC8AFE16FA717|rigid:WUrLl39vyMa1FPIxfrMmmCgdvTc	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q9UDY4	intact:EBI-27033646	intact:EBI-356960|uniprotkb:Q13431|uniprotkb:B2R824|ensembl:ENSP00000359799.5	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:dnjb4_human(display_long)|uniprotkb:DNAJB4(gene name)|psi-mi:DNAJB4(display_short)|uniprotkb:DNAJW(gene name synonym)|uniprotkb:HLJ1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1 homolog(gene name synonym)|uniprotkb:Human liver DnaJ-like protein(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033657|imex:IM-29092-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_008965.2|ensembl:ENSG00000162616.9(gene)|ensembl:ENST00000370763.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0009408""(response to heat)|go:""GO:0030018""(Z disc)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|interpro:IPR051339|mint:Q9UDY4|refseq:NP_001304028.1|refseq:NP_001304029.1|refseq:NP_001304030.1|refseq:NP_001304031.1|refseq:NP_001304032.1|panther:PTHR24078(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/27	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:gN0zBtJQiTN+YYSAtMk1mddNWLU9606	intact-crc:E40CC8AFE16FA717|rigid:WUrLl39vyMa1FPIxfrMmmCgdvTc	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:O95466	intact:EBI-27033646	intact:EBI-720020|uniprotkb:Q6DKG5|uniprotkb:Q6IBP3|uniprotkb:Q86UH1|uniprotkb:Q8N671|uniprotkb:Q8TDH1|uniprotkb:Q96H10|uniprotkb:D2DGW2|ensembl:ENSP00000329219.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:fmnl1_human(display_long)|uniprotkb:Leukocyte formin(gene name synonym)|uniprotkb:CLL-associated antigen KW-13(gene name synonym)|uniprotkb:FMNL1(gene name)|psi-mi:FMNL1(display_short)|uniprotkb:C17orf1(gene name synonym)|uniprotkb:C17orf1B(gene name synonym)|uniprotkb:FMNL(gene name synonym)|uniprotkb:FRL1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033657|imex:IM-29092-23	intact-miscore:0.68	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_005883.2|ensembl:ENSG00000184922.15(gene)|ensembl:ENST00000331495.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032059""(bleb)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR043592|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:O95466|rcsb pdb:4YDH|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:XP_006722126.1|refseq:XP_006722133.1|panther:PTHR45857(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/27	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:SN1xgeqb5yPUjiaEv2H/kyDrD4c9606	intact-crc:E40CC8AFE16FA717|rigid:WUrLl39vyMa1FPIxfrMmmCgdvTc	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:O00767	intact:EBI-27033646	intact:EBI-2684237|uniprotkb:Q5W037|uniprotkb:B2R5U0|uniprotkb:Q96KF6|uniprotkb:Q53GR9|uniprotkb:Q9Y695|uniprotkb:Q9BS07|uniprotkb:Q16150|uniprotkb:Q6GSS4|uniprotkb:Q5W038|uniprotkb:D3DR68|ensembl:ENSP00000359380.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	"psi-mi:scd_human(display_long)|uniprotkb:""Delta(9)-desaturase""(gene name synonym)|uniprotkb:Fatty acid desaturase(gene name synonym)|uniprotkb:Acyl-CoA desaturase(gene name synonym)|uniprotkb:FADS5(gene name synonym)|uniprotkb:SCD1(gene name synonym)|uniprotkb:SCDOS(gene name synonym)|uniprotkb:SCD(gene name)|psi-mi:SCD(display_short)"	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033657|imex:IM-29092-23	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_005054.3|ensembl:ENSG00000099194.6(gene)|ensembl:ENST00000370355.3(transcript)|go:""GO:0004768""(stearoyl-CoA 9-desaturase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006636""(unsaturated fatty acid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0032896""(palmitoyl-CoA 9-desaturase activity)|go:""GO:0070542""(response to fatty acid)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1903966""(monounsaturated fatty acid biosynthetic process)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|mint:O00767|rcsb pdb:4ZYO|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|reactome:R-HSA-9841922|panther:PTHR11351(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/27	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:GeF7PMgZb07js39m6ykSSmFuIUA9606	intact-crc:E40CC8AFE16FA717|rigid:WUrLl39vyMa1FPIxfrMmmCgdvTc	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q8WUY3	intact:EBI-27033646	intact:EBI-743880|intact:EBI-28967347|uniprotkb:Q5T304|uniprotkb:B4DQH8|uniprotkb:O15073|uniprotkb:Q58A63|uniprotkb:Q5T476|uniprotkb:Q6T2V6|uniprotkb:Q6T2V7|uniprotkb:Q8N665|uniprotkb:Q5JUB6|uniprotkb:B3KYC4|ensembl:ENSP00000365908.3	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:prun2_human(display_long)|uniprotkb:PRUNE2(gene name)|psi-mi:PRUNE2(display_short)|uniprotkb:C9orf65(gene name synonym)|uniprotkb:BMCC1(gene name synonym)|uniprotkb:BNIPXL(gene name synonym)|uniprotkb:KIAA0367(gene name synonym)|uniprotkb:BNIP2 motif-containing molecule at the C-terminal region 1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033657|imex:IM-29092-23	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_056040.2|refseq:NP_001294976.1|refseq:NP_001294977.1|refseq:NP_001294978.1|refseq:NP_001294979.1|refseq:NP_001294980.1|refseq:XP_011516625.1|ensembl:ENSG00000106772.19(gene)|ensembl:ENST00000376718.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0016462""(pyrophosphatase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR004097(DHHA2)|interpro:IPR022181|interpro:IPR036865|interpro:IPR038222|interpro:IPR038763|mint:Q8WUY3|panther:PTHR12112(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/27	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:rK1uzBXTEpJHKZ6p6Y0EgfdLibw9606	intact-crc:E40CC8AFE16FA717|rigid:WUrLl39vyMa1FPIxfrMmmCgdvTc	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61586	intact:EBI-10760263	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P11279	intact:EBI-10760263	intact:EBI-2805407|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40|ensembl:ENSP00000333298.4|uniprotkb:B4DWL3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_005552.3|ensembl:ENSG00000185896.11(gene)|ensembl:ENST00000332556.5(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0001618""(virus receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0044754""(autolysosome)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0061474""(phagolysosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072594""(establishment of protein localization to organelle)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0140507""(granzyme-mediated programmed cell death signaling pathway)|go:""GO:1902513""(regulation of organelle transport along microtubule)|interpro:IPR002000(""Lysosome-associated membrane glycoprotein (Lamp)/CD68"")|interpro:IPR018134|interpro:IPR048524|interpro:IPR048528|mint:P11279|rcsb pdb:8ATH|rcsb pdb:8FY5|rcsb pdb:8FYF|reactome:R-HSA-6798695|dip:DIP-44670N|panther:PTHR11506(orthology-group)"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q93050	intact:EBI-10760263	intact:EBI-2891238|uniprotkb:Q8N5G7|uniprotkb:Q9NSX0|intact:EBI-4324496|uniprotkb:B7Z3B7|ensembl:ENSP00000342951.3|ensembl:ENSP00000515539.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:vpp1_human(display_long)|uniprotkb:ATP6V0A1(gene name)|psi-mi:ATP6V0A1(display_short)|uniprotkb:ATP6N1(gene name synonym)|uniprotkb:ATP6N1A(gene name synonym)|uniprotkb:VPP1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"go:""GO:1902600""(proton transmembrane transport)|ensembl:ENSG00000033627.18(gene)|ensembl:ENST00000343619.9(transcript)|ensembl:ENST00000703901.1(transcript)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0042470""(melanosome)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051117""(ATPase binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|mint:Q93050|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:NP_001123492.1|refseq:NP_001123493.1|refseq:NP_005168.2|efo:""Orphanet:528084""|panther:PTHR11629(orthology-group)"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:3htDhXCA9potj7i32HoA2j3Sfqw9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61421	intact:EBI-10760263	intact:EBI-954063|uniprotkb:P12953|uniprotkb:Q02547|ensembl:ENSP00000290949.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:va0d1_human(display_long)|uniprotkb:Vacuolar proton pump subunit d 1(gene name synonym)|uniprotkb:V-ATPase AC39 subunit(gene name synonym)|uniprotkb:V-ATPase 40 kDa accessory protein(gene name synonym)|uniprotkb:32 kDa accessory protein(gene name synonym)|uniprotkb:ATP6V0D1(gene name)|psi-mi:ATP6V0D1(display_short)|uniprotkb:ATP6D(gene name synonym)|uniprotkb:VPATPD(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_004682.2|dip:DIP-47435N|ensembl:ENSG00000159720.13(gene)|ensembl:ENST00000290949.8(transcript)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007034""(vacuolar transport)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0033181""(plasma membrane proton-transporting V-type ATPase complex)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0043679""(axon terminus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|mint:P61421|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|rcsb pdb:7UNF|reactome:R-HSA-1222556|reactome:R-HSA-381038|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-9857377|panther:PTHR11028(orthology-group)"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:3a/yIxEF9LMwAZUR3npGQrw8xNo9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P08195	intact:EBI-10760263	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O15118	intact:EBI-10760263	intact:EBI-2368710|uniprotkb:Q9P130|ensembl:ENSP00000269228.4|uniprotkb:B4DET3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:npc1_human(display_long)|uniprotkb:NPC1(gene name)|psi-mi:NPC1(display_short)|uniprotkb:Niemann-Pick C1 protein(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000141458.13(gene)|ensembl:ENST00000269228.10(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001889""(liver development)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007628""(adult walking behavior)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008206""(bile acid metabolic process)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010467""(gene expression)|go:""GO:0010878""(cholesterol storage)|go:""GO:0012501""(programmed cell death)|go:""GO:0015485""(cholesterol binding)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0022008""(neurogenesis)|go:""GO:0030299""(intestinal cholesterol absorption)|go:""GO:0030301""(cholesterol transport)|go:""GO:0031579""(membrane raft organization)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032365""(intracellular lipid transport)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0045121""(membrane raft)|go:""GO:0046686""(response to cadmium ion)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0120020""(cholesterol transfer activity)|go:""GO:1904036""(negative regulation of epithelial cell apoptotic process)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:2000900""(cyclodextrin metabolic process)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR004765(Niemann-Pick C type protein)|interpro:IPR032190|interpro:IPR053956|interpro:IPR053958|mint:O15118|rcsb pdb:3GKH|rcsb pdb:3GKI|rcsb pdb:3GKJ|rcsb pdb:3JD8|rcsb pdb:5F18|rcsb pdb:5F1B|rcsb pdb:5HNS|rcsb pdb:5JNX|rcsb pdb:5KWY|rcsb pdb:5U73|rcsb pdb:5U74|rcsb pdb:6UOX|rcsb pdb:6W5R|rcsb pdb:6W5S|rcsb pdb:6W5T|rcsb pdb:6W5U|rcsb pdb:6W5V|rcsb pdb:8EUS|reactome:R-HSA-8964038|refseq:NP_000262.2|dip:DIP-53217N|efo:""Orphanet:216972""|efo:""Orphanet:216975""|efo:""Orphanet:216978""|efo:""Orphanet:216981""|efo:""Orphanet:216986""|panther:PTHR45727(orthology-group)"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:3kG4MGzeShC2D5FsPoZZm1lEGlk9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q13393	intact:EBI-10760263	intact:EBI-2827556|ensembl:ENSP00000342793.4	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:pld1_human(display_long)|uniprotkb:PLD1(gene name)|psi-mi:PLD1(display_short)|uniprotkb:Choline phosphatase 1(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:XP_011511199.1|refseq:NP_002653.1|refseq:XP_005247590.1|refseq:XP_005247591.1|ensembl:ENSG00000075651.17(gene)|ensembl:ENST00000351298.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004630""(phospholipase D activity)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006654""(phosphatidic acid biosynthetic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0009395""(phospholipid catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031670""(cellular response to nutrient)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032534""(regulation of microvillus assembly)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0098693""(regulation of synaptic vesicle cycle)|go:""GO:0098981""(cholinergic synapse)|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015679(Phospholipase D)|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR025202|interpro:IPR036871|mint:Q13393|rcsb pdb:6U8Z|reactome:R-HSA-1483148|reactome:R-HSA-1483166|reactome:R-HSA-2029485|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-40821N|panther:PTHR18896(orthology-group)"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:4TlTbVJTGGyEAcq/Gby1STgUH4Q9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P22059	intact:EBI-10760263	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q14254	intact:EBI-10760263	intact:EBI-348613|ensembl:ENSP00000378368.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:flot2_human(display_long)|uniprotkb:FLOT2(gene name)|psi-mi:FLOT2(display_short)|uniprotkb:ESA1(gene name synonym)|uniprotkb:M17S1(gene name synonym)|uniprotkb:Epidermal surface antigen(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_004466.2|ensembl:ENSG00000132589.16(gene)|ensembl:ENST00000394908.9(transcript)|go:""GO:0001931""(uropod)|go:""GO:0002020""(protease binding)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0008544""(epidermis development)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016600""(flotillin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031982""(vesicle)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0044860""(protein localization to plasma membrane raft)|go:""GO:0045661""(regulation of myoblast differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098937""(anterograde dendritic transport)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1902992""(negative regulation of amyloid precursor protein catabolic process)|go:""GO:1903905""(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:Q14254|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9696264|reactome:R-HSA-9696273|refseq:XP_016879883.1|refseq:XP_016879884.1|panther:PTHR13806(orthology-group)"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:P9htlLzTYk+eDKKesqCEPe/1BJA9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P62745	intact:EBI-10760263	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|ensembl:ENSP00000272233.4|uniprotkb:B2R692	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_004031.1|ensembl:ENSG00000143878.10(gene)|ensembl:ENST00000272233.6(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0001525""(angiogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0019003""(GDP binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032154""(cleavage furrow)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|panther:PTHR24072(orthology-group)"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q08722	intact:EBI-10760263	intact:EBI-1268321|uniprotkb:Q53Y71|uniprotkb:Q96A60|uniprotkb:A8K198|uniprotkb:D3DN59|ensembl:ENSP00000355361.5	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:cd47_human(display_long)|uniprotkb:CD47(gene name)|psi-mi:CD47(display_short)|uniprotkb:MER6(gene name synonym)|uniprotkb:Integrin-associated protein(gene name synonym)|uniprotkb:Antigenic surface determinant protein OA3(gene name synonym)|uniprotkb:Protein MER6(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036840|imex:IM-29092-142	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001768.1|refseq:NP_942088.1|ensembl:ENSG00000196776.17(gene)|ensembl:ENST00000361309.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0016477""(cell migration)|go:""GO:0022409""(positive regulation of cell-cell adhesion)|go:""GO:0032649""(regulation of type II interferon production)|go:""GO:0032653""(regulation of interleukin-10 production)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0035579""(specific granule membrane)|go:""GO:0045428""(regulation of nitric oxide biosynthetic process)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071349""(cellular response to interleukin-12)|go:""GO:0086080""(protein binding involved in heterotypic cell-cell adhesion)|go:""GO:0098632""(cell-cell adhesion mediator activity)|go:""GO:1904669""(ATP export)|go:""GO:2000439""(positive regulation of monocyte extravasation)|interpro:IPR006704(CD47 integrin associated protein)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013147(CD47 transmembrane)|interpro:IPR013270(CD47 immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037805|mint:Q08722|rcsb pdb:2JJS|rcsb pdb:2JJT|rcsb pdb:2VSC|rcsb pdb:4CMM|rcsb pdb:4KJY|rcsb pdb:5IWL|rcsb pdb:5TZ2|rcsb pdb:5TZT|rcsb pdb:5TZU|rcsb pdb:7MYZ|rcsb pdb:7WN8|rcsb pdb:7XJF|rcsb pdb:7YGG|rcsb pdb:8RP8|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-391160|reactome:R-HSA-6798695|dip:DIP-39948N|panther:PTHR10613(orthology-group)"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/10	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:2hhmwvfeDFe7KHXzsBOJkjo2pjk9606	intact-crc:EA2CE9404839203F|rigid:m3UXPgfo7cRMqHkkGu2ct0UJLBU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6AZQ1	uniprotkb:P62195	intact:EBI-27033737	intact:EBI-357745|ensembl:ENSP00000310572.6|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033745|imex:IM-29092-65	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000087191.14(gene)|ensembl:ENST00000310144.11(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008134""(transcription factor binding)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031531""(thyrotropin-releasing hormone receptor binding)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|panther:PTHR23073(orthology-group)|refseq:NP_001186092.1|refseq:NP_002796.4|dip:DIP-36645N"	-	-	crc64:29C6410C4A85A7F7	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	intact-crc:AB6EDD474E257253|rigid:tCDHu8US6P17rsYhKK1gzxoUSJI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6AZQ1	uniprotkb:P04083	intact:EBI-27033737	intact:EBI-354007|ensembl:ENSP00000257497.6|ensembl:ENSP00000366109.1|uniprotkb:B5BU38	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033745|imex:IM-29092-65	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_000691.1|ensembl:ENSG00000135046.15(gene)|ensembl:ENST00000257497.11(transcript)|ensembl:ENST00000376911.2(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002685""(regulation of leukocyte migration)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007187""(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:""GO:0008289""(lipid binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014839""(myoblast migration involved in skeletal muscle regeneration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031514""(motile cilium)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032652""(regulation of interleukin-1 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0033031""(positive regulation of neutrophil apoptotic process)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045627""(positive regulation of T-helper 1 cell differentiation)|go:""GO:0045629""(negative regulation of T-helper 2 cell differentiation)|go:""GO:0045920""(negative regulation of exocytosis)|go:""GO:0046632""(alpha-beta T cell differentiation)|mint:P04083|go:""GO:0046883""(regulation of hormone secretion)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050482""(arachidonate secretion)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071621""(granulocyte chemotaxis)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|refseq:XP_011516911.1|dip:DIP-32875N|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	intact-crc:AB6EDD474E257253|rigid:tCDHu8US6P17rsYhKK1gzxoUSJI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6AZQ1	uniprotkb:P06493	intact:EBI-27033737	intact:EBI-444308|ensembl:ENSP00000378699.3|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033745|imex:IM-29092-65	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000170312.17(gene)|ensembl:ENST00000395284.8(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000307""(cyclin-dependent protein kinase holoenzyme complex)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003682""(chromatin binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004693""(cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005876""(spindle microtubule)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0007077""(mitotic nuclear membrane disassembly)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007344""(pronuclear fusion)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010971""(positive regulation of G2/M transition of mitotic cell cycle)|go:""GO:0014038""(regulation of Schwann cell differentiation)|go:""GO:0014075""(response to amine)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0016477""(cell migration)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0030261""(chromosome condensation)|go:""GO:0030332""(cyclin binding)|go:""GO:0030496""(midbody)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0034501""(protein localization to kinetochore)|go:""GO:0035173""(histone kinase activity)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045471""(response to ethanol)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046686""(response to cadmium ion)|go:""GO:0046688""(response to copper ion)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048511""(rhythmic process)|go:""GO:0048678""(response to axon injury)|go:""GO:0051301""(cell division)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0062033""(positive regulation of mitotic sister chromatid segregation)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090166""(Golgi disassembly)|go:""GO:0097121""(cyclin A1-CDK1 complex)|go:""GO:0097122""(cyclin A2-CDK1 complex)|go:""GO:0097125""(cyclin B1-CDK1 complex)|go:""GO:0097472""(cyclin-dependent protein kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140833""(RNA polymerase II CTD heptapeptide repeat Y1 kinase activity)|go:""GO:0140834""(RNA polymerase II CTD heptapeptide repeat S2 kinase activity)|go:""GO:0140835""(RNA polymerase II CTD heptapeptide repeat T4 kinase activity)|go:""GO:0140836""(RNA polymerase II CTD heptapeptide repeat S5 kinase activity)|go:""GO:0140837""(RNA polymerase II CTD heptapeptide repeat S7 kinase activity)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902423""(regulation of attachment of mitotic spindle microtubules to kinetochore)|go:""GO:1902850""(microtubule cytoskeleton organization involved in mitosis)|go:""GO:1905448""(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050108|mint:P06493|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|rcsb pdb:6GU7|rcsb pdb:6TWN|rcsb pdb:7NJ0|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|reactome:R-HSA-9833482|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N|panther:PTHR24056(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606	intact-crc:AB6EDD474E257253|rigid:tCDHu8US6P17rsYhKK1gzxoUSJI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6AZQ1	uniprotkb:O94887	intact:EBI-27033737	intact:EBI-2806886|uniprotkb:Q53QM5|uniprotkb:Q9UFE7|uniprotkb:Q8WU27|uniprotkb:B7Z6J8|uniprotkb:F5GZ84|ensembl:ENSP00000264042.3	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:farp2_human(display_long)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:PLEKHC3(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 3(gene name synonym)|uniprotkb:FERM domain-including RhoGEF(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033745|imex:IM-29092-65	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001269912.1|refseq:NP_001269913.1|refseq:NP_055623.1|ensembl:ENSG00000006607.14(gene)|ensembl:ENST00000264042.8(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007155""(cell adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0016322""(neuron remodeling)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0022405""(hair cycle process)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0033623""(regulation of integrin activation)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071800""(podosome assembly)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|interpro:IPR051835|mint:O94887|reactome:R-HSA-399955|reactome:R-HSA-9013149|panther:PTHR45858(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606	intact-crc:AB6EDD474E257253|rigid:tCDHu8US6P17rsYhKK1gzxoUSJI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q9NTJ5	intact:EBI-27033737	intact:EBI-3917235|uniprotkb:Q7LA14|uniprotkb:A8K527|uniprotkb:Q96AX7|uniprotkb:Q9NQ46|uniprotkb:Q9NQ57|uniprotkb:O94935|uniprotkb:Q7LA22|ensembl:ENSP00000373713.4|uniprotkb:B4DK71	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:sac1_human(display_long)|uniprotkb:SACM1L(gene name)|psi-mi:SACM1L(display_short)|uniprotkb:KIAA0851(gene name synonym)|uniprotkb:Suppressor of actin mutations 1-like protein(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)|uniprotkb:SAC1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033745|imex:IM-29092-65	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011531802.1|refseq:NP_054735.3|ensembl:ENSG00000211456.14(gene)|ensembl:ENST00000389061.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004438""(phosphatidylinositol-3-phosphate phosphatase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0016791""(phosphatase activity)|go:""GO:0034596""(phosphatidylinositol phosphate 4-phosphatase activity)|go:""GO:0043812""(phosphatidylinositol-4-phosphate phosphatase activity)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|go:""GO:0140268""(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR002013(Synaptojanin, N-terminal)|mint:Q9NTJ5|reactome:R-HSA-1483248|reactome:R-HSA-1660514|refseq:NP_001306001.1|refseq:NP_001306002.1|panther:PTHR45662(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:aaI+D/4SJcwZxWqoxDJ81dA60nU9606	intact-crc:AB6EDD474E257253|rigid:tCDHu8US6P17rsYhKK1gzxoUSJI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q9UGY1	intact:EBI-27033737	intact:EBI-716098|ensembl:ENSP00000352021.4|ensembl:ENSP00000403059.1|ensembl:ENSP00000482349.1	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:nol12_human(display_long)|uniprotkb:NOL12(gene name)|psi-mi:NOL12(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033745|imex:IM-29092-65	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_077289.1|ensembl:ENSG00000273899.5(gene)|ensembl:ENST00000359114.9(transcript)|ensembl:ENST00000438329.5(transcript)|ensembl:ENST00000611699.1(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0019843""(rRNA binding)|go:""GO:0042802""(identical protein binding)|interpro:IPR019186|mint:Q9UGY1|reactome:R-HSA-6791226|panther:PTHR14577(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:yYrOadt76SuArmi4/Wfj2rFguNQ9606	intact-crc:AB6EDD474E257253|rigid:tCDHu8US6P17rsYhKK1gzxoUSJI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q01082	intact:EBI-27033737	intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259.4	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033745|imex:IM-29092-65	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:528084""|ensembl:ENSG00000115306.17(gene)|ensembl:ENST00000356805.9(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0007417""(central nervous system development)|go:""GO:0008091""(spectrin)|go:""GO:0014069""(postsynaptic density)|go:""GO:0014731""(spectrin-associated cytoskeleton)|go:""GO:0021556""(central nervous system formation)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030506""(ankyrin binding)|go:""GO:0030673""(axolemma)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031430""(M band)|go:""GO:0032437""(cuticular plate)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0042995""(cell projection)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045296""(cadherin binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051020""(GTPase binding)|go:""GO:0051693""(actin filament capping)|go:""GO:0060390""(regulation of SMAD protein signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071709""(membrane assembly)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|refseq:NP_003119.2|refseq:NP_842565.2|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N|panther:PTHR11915(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606	intact-crc:AB6EDD474E257253|rigid:tCDHu8US6P17rsYhKK1gzxoUSJI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q15758	intact:EBI-27033185	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|ensembl:ENSG00000105281.13(gene)|ensembl:ENST00000542575.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0006868""(glutamine transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010585""(glutamine secretion)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015183""(L-aspartate transmembrane transporter activity)|go:""GO:0015186""(L-glutamine transmembrane transporter activity)|go:""GO:0015194""(L-serine transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0016020""(membrane)|go:""GO:0022834""(ligand-gated channel activity)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070207""(protein homotrimerization)|go:""GO:0140009""(L-aspartate import across plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1903803""(L-glutamine import across plasma membrane)|interpro:IPR001991(""Sodium:dicarboxylate symporter"")|interpro:IPR018107|interpro:IPR036458|interpro:IPR050746|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|rcsb pdb:7BCQ|rcsb pdb:7BCS|rcsb pdb:7BCT|rcsb pdb:8OUD|rcsb pdb:8OUH|rcsb pdb:8OUJ|rcsb pdb:8QRO|rcsb pdb:8QRP|rcsb pdb:8QRQ|rcsb pdb:8QRR|rcsb pdb:8QRS|rcsb pdb:8QRU|rcsb pdb:8QRV|rcsb pdb:8QRW|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|panther:PTHR11958(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P04083	intact:EBI-27033185	intact:EBI-354007|ensembl:ENSP00000257497.6|ensembl:ENSP00000366109.1|uniprotkb:B5BU38	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_000691.1|ensembl:ENSG00000135046.15(gene)|ensembl:ENST00000257497.11(transcript)|ensembl:ENST00000376911.2(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002685""(regulation of leukocyte migration)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007187""(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:""GO:0008289""(lipid binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014839""(myoblast migration involved in skeletal muscle regeneration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031514""(motile cilium)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032652""(regulation of interleukin-1 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0033031""(positive regulation of neutrophil apoptotic process)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045627""(positive regulation of T-helper 1 cell differentiation)|go:""GO:0045629""(negative regulation of T-helper 2 cell differentiation)|go:""GO:0045920""(negative regulation of exocytosis)|go:""GO:0046632""(alpha-beta T cell differentiation)|mint:P04083|go:""GO:0046883""(regulation of hormone secretion)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050482""(arachidonate secretion)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071621""(granulocyte chemotaxis)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|refseq:XP_011516911.1|dip:DIP-32875N|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q8NEW0	intact:EBI-27033185	intact:EBI-1043569|uniprotkb:Q8TCH2|uniprotkb:B2R949|uniprotkb:D3DT61|ensembl:ENSP00000350278.4|ensembl:ENSP00000359130.4	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:znt7_human(display_long)|uniprotkb:SLC30A7(gene name)|psi-mi:SLC30A7(display_short)|uniprotkb:ZNT7(gene name synonym)|uniprotkb:ZNTL2(gene name synonym)|uniprotkb:Znt-like transporter 2(gene name synonym)|uniprotkb:Solute carrier family 30 member 7(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001138356.1|refseq:NP_598003.2|refseq:XP_016855889.1|ensembl:ENSG00000162695.13(gene)|ensembl:ENST00000357650.9(transcript)|ensembl:ENST00000370112.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005385""(zinc ion transmembrane transporter activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031982""(vesicle)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:1904257""(zinc ion import into Golgi lumen)|go:""GO:1990674""(Golgi cis cisterna membrane)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR045316|mint:Q8NEW0|rcsb pdb:8J7T|rcsb pdb:8J7U|rcsb pdb:8J7V|rcsb pdb:8J7W|rcsb pdb:8J7X|rcsb pdb:8J7Y|rcsb pdb:8J80|panther:PTHR45755(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:/okPwOjluCDoM8a5uHoixAyRc8E9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P42345	intact:EBI-27033185	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|intact:EBI-28989074|ensembl:ENSP00000354558.4|ensembl:ENSP00000515200.2	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)|uniprotkb:Tyrosine-protein kinase mTOR(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:269001""|efo:""Orphanet:269008""|efo:""Orphanet:457485""|efo:""Orphanet:99802""|ensembl:ENSG00000198793.14(gene)|ensembl:ENST00000361445.9(transcript)|ensembl:ENST00000703143.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000822""(inositol hexakisphosphate binding)|go:""GO:0001002""(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:""GO:0001003""(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:""GO:0001006""(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:""GO:0001156""(TFIIIC-class transcription factor complex binding)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002296""(T-helper 1 cell lineage commitment)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003179""(heart valve morphogenesis)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006112""(energy reserve metabolic process)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007281""(germ cell development)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009408""(response to heat)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010831""(positive regulation of myotube differentiation)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0016605""(PML body)|go:""GO:0019228""(neuronal action potential)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030425""(dendrite)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031529""(ruffle organization)|go:""GO:0031641""(regulation of myelination)|go:""GO:0031648""(protein destabilization)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0031670""(cellular response to nutrient)|go:""GO:0031929""(TOR signaling)|go:""GO:0031931""(TORC1 complex)|go:""GO:0031932""(TORC2 complex)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0038203""(TORC2 signaling)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043200""(response to amino acid)|go:""GO:0043276""(anoikis)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045670""(regulation of osteoclast differentiation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0045945""(positive regulation of transcription by RNA polymerase III)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046889""(positive regulation of lipid biosynthetic process)|go:""GO:0048266""(behavioral response to pain)|go:""GO:0048511""(rhythmic process)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050882""(voluntary musculoskeletal movement)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055013""(cardiac muscle cell development)|go:""GO:0060048""(cardiac muscle contraction)|go:""GO:0061431""(cellular response to methionine)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071470""(cellular response to osmotic stress)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090559""(regulation of membrane permeability)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1903691""(positive regulation of wound healing, spreading of epidermal cells)|go:""GO:1904059""(regulation of locomotor rhythm)|go:""GO:1904690""(positive regulation of cytoplasmic translational initiation)|go:""GO:1905671""(regulation of lysosome organization)|go:""GO:1905672""(negative regulation of lysosome organization)|go:""GO:1905857""(positive regulation of pentose-phosphate shunt)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990253""(cellular response to leucine starvation)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|interpro:IPR050517|mint:P42345|rcsb pdb:1AUE|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|rcsb pdb:7EPD|rcsb pdb:7OWG|rcsb pdb:7PE7|rcsb pdb:7PE8|rcsb pdb:7PE9|rcsb pdb:7PEA|rcsb pdb:7PEB|rcsb pdb:7PEC|rcsb pdb:7TZO|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8ER6|rcsb pdb:8ER7|rcsb pdb:8ERA|rcsb pdb:8PPZ|rcsb pdb:8RCH|rcsb pdb:8RCK|rcsb pdb:8RCN|rcsb pdb:9F44|rcsb pdb:9F45|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|reactome:R-HSA-9856530|refseq:NP_004949.1|refseq:XP_005263495.1|dip:DIP-790N|panther:PTHR11139(orthology-group)|ensembl:ENSP00000354558.4|ensembl:ENSP00000515200.2"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P20020	intact:EBI-27033185	intact:EBI-5279998|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|ensembl:ENSP00000392043.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000070961.17(gene)|efo:""Orphanet:528084""|ensembl:ENST00000428670.8(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0003056""(regulation of vascular associated smooth muscle contraction)|go:""GO:0005388""(P-type calcium transporter activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0015085""(calcium ion transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030501""(positive regulation of bone mineralization)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042995""(cell projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051481""(negative regulation of cytosolic calcium ion concentration)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098684""(photoreceptor ribbon synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1990034""(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P20020|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9662360|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_011536709.1|refseq:XP_016874847.1|panther:PTHR24093(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:O00469	intact:EBI-27033185	intact:EBI-1047459|uniprotkb:Q59ED2|uniprotkb:Q8N170|intact:EBI-2559757|ensembl:ENSP00000353170.3|ensembl:ENSP00000515354.1|uniprotkb:B3KWS3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:plod2_human(display_long)|uniprotkb:Lysyl hydroxylase 2(gene name synonym)|uniprotkb:PLOD2(gene name)|psi-mi:PLOD2(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000152952.14(gene)|ensembl:ENST00000360060.7(transcript)|ensembl:ENST00000703523.1(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0005506""(iron ion binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0008475""(procollagen-lysine 5-dioxygenase activity)|go:""GO:0017185""(peptidyl-lysine hydroxylation)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030867""(rough endoplasmic reticulum membrane)|go:""GO:0031418""(L-ascorbic acid binding)|go:""GO:0036211""(protein modification process)|go:""GO:0046947""(hydroxylysine biosynthetic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123(""2OG-Fe(II) oxygenase"")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|interpro:IPR044861|interpro:IPR050757|mint:O00469|reactome:R-HSA-1650814|refseq:NP_000926.2|refseq:NP_891988.1|efo:""Orphanet:2771""|panther:PTHR10730(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:sNgFtZzNoKBCz7KUhTBfMG/xxas9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P61026	intact:EBI-27033185	intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710.4	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_057215.3|ensembl:ENSG00000084733.11(gene)|ensembl:ENST00000264710.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0007409""(axonogenesis)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0019003""(GDP binding)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0031489""(myosin V binding)|go:""GO:0032593""(insulin-responsive compartment)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045200""(establishment of neuroblast polarity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070382""(exocytic vesicle)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0097051""(establishment of protein localization to endoplasmic reticulum membrane)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0099503""(secretory vesicle)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:P61026|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P55060	intact:EBI-27033185	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|ensembl:ENSP00000262982.2|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000124207.17(gene)|ensembl:ENST00000262982.3(transcript)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060|refseq:NP_001307.2|refseq:NP_001243064.1|refseq:XP_011526901.1|dip:DIP-32573N|panther:PTHR10997(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q13535	intact:EBI-27033185	intact:EBI-968983|uniprotkb:Q7KYL3|uniprotkb:Q93051|uniprotkb:Q9BXK4|uniprotkb:Q59HB2|ensembl:ENSP00000343741.4	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:atr_human(display_long)|uniprotkb:ATR(gene name)|psi-mi:ATR(display_short)|uniprotkb:FRP1(gene name synonym)|uniprotkb:Ataxia telangiectasia and Rad3-related protein(gene name synonym)|uniprotkb:FRAP-related protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:313846""|efo:""Orphanet:808""|dip:DIP-35308N|ensembl:ENSG00000175054.16(gene)|ensembl:ENST00000350721.9(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000723""(telomere maintenance)|go:""GO:0003677""(DNA binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006974""(DNA damage response)|go:""GO:0008156""(negative regulation of DNA replication)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0016605""(PML body)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0031297""(replication fork processing)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0032405""(MutLalpha complex binding)|go:""GO:0032407""(MutSalpha complex binding)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036297""(interstrand cross-link repair)|go:""GO:0043517""(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044818""(mitotic G2/M transition checkpoint)|go:""GO:0046685""(response to arsenic-containing substance)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0051081""(nuclear membrane disassembly)|go:""GO:0070198""(protein localization to chromosome, telomeric region)|go:""GO:0070310""(ATR-ATRIP complex)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090399""(replicative senescence)|go:""GO:0090734""(site of DNA damage)|go:""GO:0097694""(establishment of RNA localization to telomere)|go:""GO:0097695""(establishment of protein-containing complex localization to telomere)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1904884""(positive regulation of telomerase catalytic core complex assembly)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000779""(regulation of double-strand break repair)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021133|interpro:IPR036940|interpro:IPR050517|mint:Q13535|rcsb pdb:5YZ0|reactome:R-HSA-1221632|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6783310|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9709570|refseq:NP_001175.2|refseq:XP_016862132.1|panther:PTHR11139(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:ZYzDNmnxcK+RJN42KfgQZlxGACU9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q7L1Q6	intact:EBI-27033185	intact:EBI-1046727|ensembl:ENSP00000386474.1|intact:EBI-1051097|uniprotkb:Q14281|uniprotkb:Q15394|uniprotkb:Q9BUY0|uniprotkb:B4DLZ8|uniprotkb:B4DWF7|intact:EBI-21351780	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:5mp2_human(display_long)|uniprotkb:BZW1(gene name)|psi-mi:BZW1(display_short)|uniprotkb:BZAP45(gene name synonym)|uniprotkb:KIAA0005(gene name synonym)|uniprotkb:Protein Orf(gene name synonym)|uniprotkb:5MP2(gene name synonym)|uniprotkb:Basic leucine zipper and W2 domain-containing protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000082153.18(gene)|ensembl:ENST00000409600.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016020""(membrane)|go:""GO:0045296""(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|interpro:IPR051245|mint:Q7L1Q6|refseq:NP_001193996.1|refseq:NP_055485.2|refseq:NP_001193997.1|refseq:NP_001193998.1|refseq:NP_001308617.1|refseq:NP_001308619.1|refseq:NP_001308620.1|refseq:NP_001308622.1|refseq:NP_001308623.1|panther:PTHR14208(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:4dzFp6AN4tymPA5rHNYlHCCmSaY9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q92616	intact:EBI-27033185	intact:EBI-356221|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692|ensembl:ENSP00000300648.6	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_006827.1|ensembl:ENSG00000089154.11(gene)|ensembl:ENST00000300648.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0006417""(regulation of translation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016020""(membrane)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0055106""(ubiquitin-protein transferase regulator activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0140469""(GCN2-mediated signaling)|go:""GO:0160127""(protein-RNA covalent cross-linking repair)|go:""GO:0170011""(stalled ribosome sensor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|panther:PTHR23346(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:aXrR83M54Nh1pnmdgL71NurSSfI9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q00325	intact:EBI-27033185	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|uniprotkb:Q7Z7N7|uniprotkb:B3KS34|ensembl:ENSP00000228318.3|ensembl:ENSP00000447310.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:s25a3_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Phosphate carrier protein, mitochondrial(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR45671(orthology-group)|ensembl:ENSG00000075415.15(gene)|ensembl:ENST00000228318.8(transcript)|ensembl:ENST00000551917.5(transcript)|go:""GO:0005315""(phosphate transmembrane transporter activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0015317""(""phosphate:proton symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0035435""(phosphate ion transmembrane transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990547""(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|efo:""Orphanet:91130"""	-	-	crc64:78714C85931B22D5	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q9NTJ5	intact:EBI-27033185	intact:EBI-3917235|uniprotkb:Q7LA14|uniprotkb:A8K527|uniprotkb:Q96AX7|uniprotkb:Q9NQ46|uniprotkb:Q9NQ57|uniprotkb:O94935|uniprotkb:Q7LA22|ensembl:ENSP00000373713.4|uniprotkb:B4DK71	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:sac1_human(display_long)|uniprotkb:SACM1L(gene name)|psi-mi:SACM1L(display_short)|uniprotkb:KIAA0851(gene name synonym)|uniprotkb:Suppressor of actin mutations 1-like protein(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)|uniprotkb:SAC1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011531802.1|refseq:NP_054735.3|ensembl:ENSG00000211456.14(gene)|ensembl:ENST00000389061.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004438""(phosphatidylinositol-3-phosphate phosphatase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0016791""(phosphatase activity)|go:""GO:0034596""(phosphatidylinositol phosphate 4-phosphatase activity)|go:""GO:0043812""(phosphatidylinositol-4-phosphate phosphatase activity)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|go:""GO:0140268""(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR002013(Synaptojanin, N-terminal)|mint:Q9NTJ5|reactome:R-HSA-1483248|reactome:R-HSA-1660514|refseq:NP_001306001.1|refseq:NP_001306002.1|panther:PTHR45662(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:aaI+D/4SJcwZxWqoxDJ81dA60nU9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q96KA5	intact:EBI-27033185	intact:EBI-3216282|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1|ensembl:ENSP00000313854.5|ensembl:ENSP00000480372.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:clp1l_human(display_long)|uniprotkb:Cleft lip and palate transmembrane protein 1-like protein(gene name synonym)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_110409.2|ensembl:ENSG00000049656.14(gene)|ensembl:ENSG00000274811.3(gene)|ensembl:ENST00000320895.10(transcript)|ensembl:ENST00000620010.3(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0017128""(phospholipid scramblase activity)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|mint:Q96KA5|panther:PTHR21347(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q9BTX1	intact:EBI-27033185	intact:EBI-2552800|uniprotkb:Q9NVZ7|uniprotkb:Q9H9T6|uniprotkb:Q9NSG3|uniprotkb:Q9NSG4|uniprotkb:Q8NB76|uniprotkb:B4DHA3|uniprotkb:B4DQQ5|uniprotkb:G3XA81|ensembl:ENSP00000360483.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:ndc1_human(display_long)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:TMEM48(gene name synonym)|uniprotkb:Transmembrane protein 48(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001162023.1|refseq:NP_060557.3|ensembl:ENSG00000058804.12(gene)|ensembl:ENST00000371429.4(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006999""(nuclear pore organization)|go:""GO:0007129""(homologous chromosome pairing at meiosis)|go:""GO:0007283""(spermatogenesis)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031965""(nuclear membrane)|go:""GO:0051028""(mRNA transport)|go:""GO:0051292""(nuclear pore complex assembly)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0070762""(nuclear pore transmembrane ring)|interpro:IPR019049|mint:Q9BTX1|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9705671|panther:PTHR13269(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:0HbFqC4o16ELLTSUfqACs1BD05I9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q9BVC6	intact:EBI-27033185	intact:EBI-1057733|ensembl:ENSP00000227525.3|ensembl:ENSP00000443990.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:tm109_human(display_long)|uniprotkb:TMEM109(gene name)|psi-mi:TMEM109(display_short)|uniprotkb:Mitsugumin-23(gene name synonym)|uniprotkb:Transmembrane protein 109(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_076997.1|ensembl:ENSG00000110108.11(gene)|ensembl:ENST00000227525.8(transcript)|ensembl:ENST00000536171.1(transcript)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0022843""(voltage-gated monoatomic cation channel activity)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0034702""(monoatomic ion channel complex)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071480""(cellular response to gamma radiation)|interpro:IPR039492|mint:Q9BVC6|panther:PTHR14550(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:KsibbFWmzuiZPpo4GqJikbMMaMQ9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P08195	intact:EBI-27033185	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:O60313	intact:EBI-27033185	intact:EBI-1054131|uniprotkb:D3DNW4|uniprotkb:E5KLJ5|uniprotkb:E5KLJ6|uniprotkb:E5KLJ7|uniprotkb:E5KLK1|uniprotkb:E5KLK2|ensembl:ENSP00000354429.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:opa1_human(display_long)|uniprotkb:Optic atrophy protein 1(gene name synonym)|uniprotkb:OPA1(gene name)|psi-mi:OPA1(display_short)|uniprotkb:KIAA0567(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:1215""|efo:""Orphanet:98673""|efo:""Orphanet:1239""|ensembl:ENSG00000198836.11(gene)|ensembl:ENST00000361828.7(transcript)|go:""GO:0000002""(mitochondrial genome maintenance)|go:""GO:0000266""(mitochondrial fission)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006915""(apoptotic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007007""(inner mitochondrial membrane organization)|go:""GO:0007601""(visual perception)|go:""GO:0008017""(microtubule binding)|go:""GO:0008053""(mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0019896""(axonal transport of mitochondrion)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030425""(dendrite)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0042407""(cristae formation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046039""(GTP metabolic process)|go:""GO:0051259""(protein complex oligomerization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0097749""(membrane tubulation)|go:""GO:0140523""(GTPase-dependent fusogenic activity)|go:""GO:0180020""(membrane bending activity)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990627""(mitochondrial inner membrane fusion)|go:""GO:2000330""(positive regulation of T-helper 17 cell lineage commitment)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR045063|interpro:IPR045817|mint:O60313|rcsb pdb:6JTG|rcsb pdb:8CT1|rcsb pdb:8CT9|rcsb pdb:8EEW|rcsb pdb:8EF7|rcsb pdb:8EFF|rcsb pdb:8EFR|rcsb pdb:8EFS|rcsb pdb:8EFT|reactome:R-HSA-169911|reactome:R-HSA-9837999|refseq:NP_056375.2|refseq:NP_570844.1|refseq:NP_570846.1|refseq:NP_570847.2|refseq:NP_570849.2|refseq:NP_570850.2|panther:PTHR11566(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:1VmujqR2PEGFIgK9mV+8g57wVb89606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q10471	intact:EBI-27033185	intact:EBI-10226985|uniprotkb:A8K1Y3|uniprotkb:C5HU00|uniprotkb:Q9NPY4|uniprotkb:B7Z8V8|ensembl:ENSP00000355632.4	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	"psi-mi:galt2_human(display_long)|uniprotkb:GALNT2(gene name)|psi-mi:GALNT2(display_short)|uniprotkb:Polypeptide GalNAc transferase 2(gene name synonym)|uniprotkb:Protein-UDP acetylgalactosaminyltransferase 2(gene name synonym)|uniprotkb:""UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2""(gene name synonym)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001278795.1|refseq:NP_004472.1|panther:PTHR11675(orthology-group)|ensembl:ENSG00000143641.10(gene)|ensembl:ENST00000366672.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004653""(polypeptide N-acetylgalactosaminyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005795""(Golgi stack)|go:""GO:0006493""(protein O-linked glycosylation)|go:""GO:0016020""(membrane)|go:""GO:0016266""(O-glycan processing)|go:""GO:0018242""(protein O-linked glycosylation via serine)|go:""GO:0018243""(protein O-linked glycosylation via threonine)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051604""(protein maturation)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035992|interpro:IPR045885|mint:Q10471|rcsb pdb:2FFU|rcsb pdb:2FFV|rcsb pdb:4D0T|rcsb pdb:4D0Z|rcsb pdb:4D11|rcsb pdb:5AJN|rcsb pdb:5AJO|rcsb pdb:5AJP|rcsb pdb:5FV9|rcsb pdb:5NDF|rcsb pdb:6E7I|rcsb pdb:6EGS|rcsb pdb:6NQT|reactome:R-HSA-6811436|reactome:R-HSA-913709"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:z7hqeQjq7k5iQZfnLHZ4ioplKPU9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:O15427	intact:EBI-27033185	intact:EBI-7600166|uniprotkb:Q2M1P8|intact:MINT-4526381|uniprotkb:B3KXG8|ensembl:ENSP00000376150.1|ensembl:ENSP00000376152.1|ensembl:ENSP00000462405.1|ensembl:ENSP00000463978.1|ensembl:ENSP00000464112.2|ensembl:ENSP00000464625.2|ensembl:ENSP00000482013.1|ensembl:ENSP00000483212.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:mot4_human(display_long)|uniprotkb:SLC16A3(gene name)|psi-mi:SLC16A3(display_short)|uniprotkb:MCT4(gene name synonym)|uniprotkb:Solute carrier family 16 member 3(gene name synonym)|uniprotkb:MCT3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011521909.1|refseq:NP_004198.1|refseq:NP_001193879.1|refseq:NP_001193880.1|refseq:NP_001035888.1|refseq:NP_001035887.1|refseq:NP_001193881.1|ensembl:ENSG00000141526.18(gene)|ensembl:ENST00000392339.6(transcript)|ensembl:ENST00000392341.6(transcript)|ensembl:ENST00000580189.6(transcript)|ensembl:ENST00000581287.5(transcript)|ensembl:ENST00000582743.6(transcript)|ensembl:ENST00000584689.6(transcript)|ensembl:ENST00000617373.5(transcript)|ensembl:ENST00000619321.2(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0008028""(monocarboxylic acid transmembrane transporter activity)|go:""GO:0015650""(""lactate:proton symporter activity"")|go:""GO:0015718""(monocarboxylic acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035873""(lactate transmembrane transport)|go:""GO:0042867""(pyruvate catabolic process)|go:""GO:0050833""(pyruvate transmembrane transporter activity)|go:""GO:1901475""(pyruvate transmembrane transport)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|interpro:IPR050327|mint:O15427|reactome:R-HSA-210991|reactome:R-HSA-433692|panther:PTHR11360(orthology-group)"	-	-	comment:mint|function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate|comment:homomint	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:Ipq+K2KMGnogWD9ouLcBjZ53ICs9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P18031	intact:EBI-27033185	intact:EBI-968788|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4|ensembl:ENSP00000360683.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N|ensembl:ENSG00000196396.10(gene)|ensembl:ENST00000371621.5(transcript)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0003723""(RNA binding)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0009968""(negative regulation of signal transduction)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030162""(regulation of proteolysis)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031904""(endosome lumen)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033157""(regulation of intracellular protein transport)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035791""(platelet-derived growth factor receptor-beta signaling pathway)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045296""(cadherin binding)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071732""(cellular response to nitric oxide)|go:""GO:0097443""(sorting endosome)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903896""(positive regulation of IRE1-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904753""(negative regulation of vascular associated smooth muscle cell migration)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990264""(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:""GO:2000353""(positive regulation of endothelial cell apoptotic process)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1AAX|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2F6Z|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:2NT7|rcsb pdb:2NTA|rcsb pdb:2QBP|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2QBS|rcsb pdb:2VEU|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2ZMM|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:3EB1|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QDV|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:6OMY|rcsb pdb:6PFW|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:6XE8|rcsb pdb:6XEF|rcsb pdb:6XEA|rcsb pdb:6XED|rcsb pdb:6XEE|rcsb pdb:6XEG|rcsb pdb:7FQM|rcsb pdb:7FQN|rcsb pdb:7FQO|rcsb pdb:7FQP|rcsb pdb:7FQQ|rcsb pdb:7FQR|rcsb pdb:7FQS|rcsb pdb:7FQT|rcsb pdb:7FQU|rcsb pdb:7FQV|rcsb pdb:7FQW|rcsb pdb:7FQX|rcsb pdb:7FQY|rcsb pdb:7FQZ|rcsb pdb:7FRE|rcsb pdb:7FRF|rcsb pdb:7FRG|rcsb pdb:7FRH|rcsb pdb:7FRI|rcsb pdb:7FRJ|rcsb pdb:7FRK|rcsb pdb:7FRL|rcsb pdb:7FRM|rcsb pdb:7FRN|rcsb pdb:7FRO|rcsb pdb:7FRP|rcsb pdb:7FRQ|rcsb pdb:7FRR|rcsb pdb:7FRS|rcsb pdb:7FRT|rcsb pdb:7FRU|rcsb pdb:7GS7|rcsb pdb:7GS8|rcsb pdb:7GS9|rcsb pdb:7GSA|rcsb pdb:7GSB|rcsb pdb:7GSC|rcsb pdb:7GSD|rcsb pdb:7GSE|rcsb pdb:7GSF|rcsb pdb:7GSG|rcsb pdb:7GSH|rcsb pdb:7GSI|rcsb pdb:7GSJ|rcsb pdb:7GSK|rcsb pdb:7GSL|rcsb pdb:7GSM|rcsb pdb:7GSN|rcsb pdb:7GSO|rcsb pdb:7GSQ|rcsb pdb:7GSR|rcsb pdb:7GST|rcsb pdb:7GSU|rcsb pdb:7GSV|rcsb pdb:7GSW|rcsb pdb:7GSX|rcsb pdb:7GSY|rcsb pdb:7GSZ|rcsb pdb:7GT0|rcsb pdb:7GT1|rcsb pdb:7GT2|rcsb pdb:7GT3|rcsb pdb:7GT4|rcsb pdb:7GT5|rcsb pdb:7GTI|rcsb pdb:7GT6|rcsb pdb:7GT7|rcsb pdb:7GT8|rcsb pdb:7GT9|rcsb pdb:7GTA|rcsb pdb:7GTB|rcsb pdb:7GTC|rcsb pdb:7GTD|rcsb pdb:7GTE|rcsb pdb:7GTF|rcsb pdb:7GTG|rcsb pdb:7GTH|rcsb pdb:7GTJ|rcsb pdb:7GTK|rcsb pdb:7GTL|rcsb pdb:7GTM|rcsb pdb:7GTN|rcsb pdb:7GTO|rcsb pdb:7GTP|rcsb pdb:7GTQ|rcsb pdb:7GTR|rcsb pdb:7GTS|rcsb pdb:7GTT|rcsb pdb:7GTU|rcsb pdb:7GTV|rcsb pdb:7GTW|rcsb pdb:7GTX|rcsb pdb:7GTY|rcsb pdb:7GTZ|rcsb pdb:7GU0|rcsb pdb:7GU1|rcsb pdb:7GU2|rcsb pdb:7GU3|rcsb pdb:7GU4|rcsb pdb:7GU5|rcsb pdb:7GU6|rcsb pdb:7GU7|rcsb pdb:7GU8|rcsb pdb:7GU9|rcsb pdb:7GUA|rcsb pdb:7GUB|rcsb pdb:7GUC|rcsb pdb:7KEN|rcsb pdb:7KEY|rcsb pdb:7KLX|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MKZ|rcsb pdb:7MM1|rcsb pdb:7MN7|rcsb pdb:7MN9|rcsb pdb:7MNA|rcsb pdb:7MNB|rcsb pdb:7MNC|rcsb pdb:7MND|rcsb pdb:7MNE|rcsb pdb:7MNF|rcsb pdb:7MOU|rcsb pdb:7MOV|rcsb pdb:7MOW|rcsb pdb:7RIN|rcsb pdb:7S4F|rcsb pdb:8DU7|rcsb pdb:8EXI|rcsb pdb:8EXJ|rcsb pdb:8EXK|rcsb pdb:8EXM|rcsb pdb:8EXN|rcsb pdb:8EYA|rcsb pdb:8EYB|rcsb pdb:8EYC|rcsb pdb:8F88|rcsb pdb:8G65|rcsb pdb:8G67|rcsb pdb:8G68|rcsb pdb:8G69|rcsb pdb:8G6A|rcsb pdb:8SKL|rcsb pdb:8U1E|rcsb pdb:8XOY|rcsb pdb:9C66|rcsb pdb:9CYO|rcsb pdb:9CYP|rcsb pdb:9CYQ|rcsb pdb:9CYR|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-77387|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-9860927|panther:PTHR46047(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P33176	intact:EBI-27033185	intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078.4	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004512.1|ensembl:ENSG00000170759.11(gene)|ensembl:ENST00000302418.5(transcript)|go:""GO:0003777""(microtubule motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007028""(cytoplasm organization)|go:""GO:0007411""(axon guidance)|go:""GO:0008017""(microtubule binding)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031982""(vesicle)|go:""GO:0032230""(positive regulation of synaptic transmission, GABAergic)|go:""GO:0032418""(lysosome localization)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0035617""(stress granule disassembly)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042802""(identical protein binding)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0051642""(centrosome localization)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072383""(plus-end-directed vesicle transport along microtubule)|go:""GO:0098971""(anterograde dendritic transport of neurotransmitter receptor complex)|go:""GO:0098987""(regulation of modification of synapse structure, modulating synaptic transmission)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0160040""(mitocytosis)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990048""(anterograde neuronal dense core vesicle transport)|go:""GO:1990049""(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|rcsb pdb:7RIK|rcsb pdb:8IXA|rcsb pdb:8IXB|rcsb pdb:8IXD|rcsb pdb:8IXE|rcsb pdb:8IXF|rcsb pdb:8IXG|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-9725370|reactome:R-HSA-983189|dip:DIP-29244N|panther:PTHR24115(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q07866	intact:EBI-27033185	intact:EBI-721019|uniprotkb:F8VTM4|uniprotkb:Q7RTQ3|uniprotkb:Q86V77|uniprotkb:Q86V78|uniprotkb:Q86V79|uniprotkb:Q7RTM2|uniprotkb:Q7RTM3|uniprotkb:Q7RTM5|uniprotkb:Q7RTP9|uniprotkb:Q7RTQ5|uniprotkb:Q7RTQ6|uniprotkb:Q86SF5|uniprotkb:Q86TF5|uniprotkb:Q86V74|uniprotkb:Q86V75|uniprotkb:Q86V76|uniprotkb:Q96H62|uniprotkb:A6NF62|ensembl:ENSP00000341154.6|intact:EBI-28976313	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:klc1_human(display_long)|uniprotkb:KLC1(gene name)|psi-mi:KLC1(display_short)|uniprotkb:KLC(gene name synonym)|uniprotkb:KNS2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001123579.1|refseq:NP_005543.2|refseq:NP_891553.2|ensembl:ENSG00000126214.22(gene)|ensembl:ENST00000348520.10(transcript)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0030426""(growth cone)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035617""(stress granule disassembly)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q07866|rcsb pdb:3NF1|rcsb pdb:5OJ8|rcsb pdb:7AI4|rcsb pdb:7AIE|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-9725370|reactome:R-HSA-983189|dip:DIP-40371N|panther:PTHR45783(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:T7SJbB/PScRqj74O/NH4q1KU0YM9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q9NP58	intact:EBI-27033185	intact:EBI-2115230|uniprotkb:O75542|uniprotkb:Q49A66|uniprotkb:Q59GQ5|uniprotkb:Q6ZME6|uniprotkb:Q96ME8|uniprotkb:Q9HAQ6|uniprotkb:Q9HAQ7|ensembl:ENSP00000265316.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:abcb6_human(display_long)|uniprotkb:ABCB6(gene name)|psi-mi:ABCB6(display_short)|uniprotkb:MTABC3(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:UMAT(gene name synonym)|uniprotkb:Mitochondrial ABC transporter 3(gene name synonym)|uniprotkb:Ubiquitously-expressed mammalian ABC half transporter(gene name synonym)|uniprotkb:P-glycoprotein-related protein(gene name synonym)|uniprotkb:ABC-type heme transporter ABCB6(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR24221(orthology-group)|ensembl:ENSG00000115657.14(gene)|ensembl:ENST00000265316.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005740""(mitochondrial envelope)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006778""(porphyrin-containing compound metabolic process)|go:""GO:0006779""(porphyrin-containing compound biosynthetic process)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007420""(brain development)|go:""GO:0015439""(ABC-type heme transporter activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:0015886""(heme transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0020037""(heme binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033013""(tetrapyrrole metabolic process)|go:""GO:0033162""(melanosome membrane)|go:""GO:0035351""(heme transmembrane transport)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0042168""(heme metabolic process)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|go:""GO:0043588""(skin development)|go:""GO:0046906""(tetrapyrrole binding)|go:""GO:0055085""(transmembrane transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098849""(cellular detoxification of cadmium ion)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:1903232""(melanosome assembly)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032410|interpro:IPR036640|interpro:IPR039421|mint:Q9NP58|rcsb pdb:3NH6|rcsb pdb:3NH9|rcsb pdb:3NHA|rcsb pdb:3NHB|rcsb pdb:7D7N|rcsb pdb:7D7R|rcsb pdb:7DNY|rcsb pdb:7DNZ|rcsb pdb:7EKL|rcsb pdb:7EKM|rcsb pdb:8FWK|rcsb pdb:8K7B|rcsb pdb:8K7C|rcsb pdb:8YR3|rcsb pdb:8YR4|reactome:R-HSA-1369007|reactome:R-HSA-5683371|refseq:NP_005680.1|efo:""Orphanet:241""|efo:""Orphanet:90044""|efo:""Orphanet:98938""|efo:""Orphanet:98942""|efo:""Orphanet:98943""|efo:""Orphanet:98944""|efo:""Orphanet:98945""|efo:""Orphanet:98946""|efo:""Orphanet:98947"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:3Zyw4d16oU1oT0eiAcOds3s1ZVQ9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P55011	intact:EBI-27033185	intact:EBI-2801449|uniprotkb:Q8WWH7|uniprotkb:Q8N713|ensembl:ENSP00000262461.2|intact:EBI-28983018	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	"psi-mi:s12a2_human(display_long)|uniprotkb:Na-K-2Cl cotransporter 1(gene name synonym)|uniprotkb:NKCC1(gene name synonym)|uniprotkb:Basolateral Na-K-Cl symporter(gene name synonym)|uniprotkb:SLC12A2(gene name)|psi-mi:SLC12A2(display_short)|uniprotkb:""Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2""(gene name synonym)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000064651.14(gene)|ensembl:ENST00000262461.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0006972""(hyperosmotic response)|go:""GO:0007214""(gamma-aminobutyric acid signaling pathway)|go:""GO:0008511""(""sodium:potassium:chloride symporter activity"")|go:""GO:0008519""(ammonium channel activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010818""(T cell chemotaxis)|go:""GO:0015079""(potassium ion transmembrane transporter activity)|go:""GO:0015377""(""chloride:monoatomic cation symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030321""(transepithelial chloride transport)|go:""GO:0030644""(intracellular chloride ion homeostasis)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031253""(cell projection membrane)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0035865""(cellular response to potassium ion)|go:""GO:0042995""(cell projection)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044297""(cell body)|go:""GO:0044298""(cell body membrane)|go:""GO:0045795""(positive regulation of cell volume)|go:""GO:0046873""(metal ion transmembrane transporter activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0055064""(chloride ion homeostasis)|go:""GO:0055075""(potassium ion homeostasis)|go:""GO:0055078""(sodium ion homeostasis)|go:""GO:0061044""(negative regulation of vascular wound healing)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070634""(transepithelial ammonium transport)|go:""GO:0071944""(cell periphery)|go:""GO:0072488""(ammonium transmembrane transport)|go:""GO:0098658""(inorganic anion import across plasma membrane)|go:""GO:0098659""(inorganic cation import across plasma membrane)|go:""GO:0098719""(sodium ion import across plasma membrane)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902476""(chloride transmembrane transport)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904450""(positive regulation of aspartate secretion)|go:""GO:1904464""(regulation of matrix metallopeptidase secretion)|go:""GO:1990573""(potassium ion import across plasma membrane)|go:""GO:1990869""(cellular response to chemokine)|interpro:IPR002443(Na-K-Cl co-transporter)|interpro:IPR002444(Na-K-Cl co-transporter 1)|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004842(Na-K-Cl cotransporter superfamily)|interpro:IPR013612(Amino acid permease N-terminal)|interpro:IPR018491|mint:P55011|rcsb pdb:6PZT|rcsb pdb:7D10|rcsb pdb:7MXO|rcsb pdb:7N3N|rcsb pdb:7S1X|rcsb pdb:7S1Y|rcsb pdb:7S1Z|rcsb pdb:7SFL|rcsb pdb:7SMP|rcsb pdb:7ZGO|rcsb pdb:8STE|reactome:R-HSA-426117|refseq:NP_001037.1|dip:DIP-43979N|efo:""Orphanet:633021""|efo:""Orphanet:633024""|panther:PTHR11827(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:DJ/f5e8b/aBlnCcWYxYUa/mcoFY9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q6P1M0	intact:EBI-27033185	intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000167114.13(gene)|ensembl:ENST00000300456.5(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0001579""(medium-chain fatty acid transport)|go:""GO:0001676""(long-chain fatty acid metabolic process)|go:""GO:0004467""(long-chain fatty acid-CoA ligase activity)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0007584""(response to nutrient)|go:""GO:0015245""(fatty acid transmembrane transporter activity)|go:""GO:0015908""(fatty acid transport)|go:""GO:0015909""(long-chain fatty acid transport)|go:""GO:0016020""(membrane)|go:""GO:0031526""(brush border membrane)|go:""GO:0031957""(very long-chain fatty acid-CoA ligase activity)|go:""GO:0042760""(very long-chain fatty acid catabolic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043588""(skin development)|go:""GO:0044381""(glucose import in response to insulin stimulus)|go:""GO:0044539""(long-chain fatty acid import into cell)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0047676""(arachidonate-CoA ligase activity)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0090433""(palmitoyl-CoA ligase activity)|go:""GO:0090434""(oleoyl-CoA ligase activity)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901480""(oleate transmembrane transporter activity)|go:""GO:1990379""(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR042099|interpro:IPR045851|mint:Q6P1M0|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:NP_005085.2|refseq:XP_016869711.1|efo:""Orphanet:88621""|panther:PTHR43107(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P61106	intact:EBI-27033185	intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946.4|ensembl:ENSP00000515613.1|ensembl:ENSP00000515614.1|intact:EBI-21352994	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_057406.2|ensembl:ENSG00000119396.12(gene)|ensembl:ENST00000373840.9(transcript)|ensembl:ENST00000703999.1(transcript)|ensembl:ENST00000704000.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001845""(phagolysosome assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005795""(Golgi stack)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019003""(GDP binding)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0031489""(myosin V binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0042175""(nuclear outer membrane-endoplasmic reticulum membrane network)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090382""(phagosome maturation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|interpro:IPR050209|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P33527	intact:EBI-27033185	intact:EBI-3911547|ensembl:ENSP00000382342.3|ensembl:ENSP00000483316.1|uniprotkb:O14819|uniprotkb:Q9UQ99|uniprotkb:P78419|uniprotkb:A3RJX2|uniprotkb:Q59GI9|uniprotkb:O43333|uniprotkb:Q9UQ97|uniprotkb:Q9UQA0|uniprotkb:C9JPJ4	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	"psi-mi:mrp1_human(display_long)|uniprotkb:ABCC1(gene name)|psi-mi:ABCC1(display_short)|uniprotkb:MRP(gene name synonym)|uniprotkb:MRP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 1(gene name synonym)|uniprotkb:""Leukotriene C(4) transporter""(gene name synonym)|uniprotkb:Glutathione-S-conjugate-translocating ATPase ABCC1(gene name synonym)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000103222.20(gene)|ensembl:ENSG00000278183.4(gene)|ensembl:ENST00000399410.8(transcript)|ensembl:ENST00000621144.4(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006691""(leukotriene metabolic process)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0008559""(ABC-type xenobiotic transporter activity)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0015420""(ABC-type vitamin B12 transporter activity)|go:""GO:0015431""(ABC-type glutathione S-conjugate transporter activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:0015889""(cobalamin transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030148""(sphingolipid biosynthetic process)|go:""GO:0034040""(ATPase-coupled lipid transmembrane transporter activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034634""(glutathione transmembrane transporter activity)|go:""GO:0034775""(glutathione transmembrane transport)|go:""GO:0042167""(heme catabolic process)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0042908""(xenobiotic transport)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|go:""GO:0043225""(ATPase-coupled inorganic anion transmembrane transporter activity)|go:""GO:0045332""(phospholipid translocation)|go:""GO:0046624""(sphingolipid transporter activity)|go:""GO:0046943""(carboxylic acid transmembrane transporter activity)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0055085""(transmembrane transport)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070633""(transepithelial transport)|go:""GO:0070729""(cyclic nucleotide transport)|go:""GO:0071716""(leukotriene transport)|go:""GO:0099039""(sphingolipid translocation)|go:""GO:0140115""(export across plasma membrane)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905039""(carboxylic acid transmembrane transport)|go:""GO:1990962""(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005292(""Multi drug resistance-associated protein (MRP)"")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR050173|mint:P33527|rcsb pdb:2CBZ|rcsb pdb:4C3Z|reactome:R-HSA-1660661|reactome:R-HSA-189483|reactome:R-HSA-2142691|reactome:R-HSA-382556|reactome:R-HSA-9707564|reactome:R-HSA-9753281|reactome:R-HSA-9758890|reactome:R-HSA-9818032|refseq:NP_004987.2|efo:""Orphanet:90635""|panther:PTHR24223(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:XGzXibUwQjwbAsg7ueuXS9YxUVc9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q8TCT9	intact:EBI-27033185	intact:EBI-347472|uniprotkb:Q540H8|uniprotkb:Q5JWP2|uniprotkb:Q5JWP3|uniprotkb:Q5JWP4|uniprotkb:Q5JWP5|uniprotkb:Q7Z4F2|uniprotkb:Q86Y35|uniprotkb:Q95H87|uniprotkb:Q9H110|uniprotkb:Q9H111|uniprotkb:Q15K36|uniprotkb:B2RAY5|uniprotkb:E1P5L3|ensembl:ENSP00000343032.5	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:hm13_human(display_long)|uniprotkb:HM13(gene name)|psi-mi:HM13(display_short)|uniprotkb:H13(gene name synonym)|uniprotkb:PSL3(gene name synonym)|uniprotkb:SPP(gene name synonym)|uniprotkb:Signal peptide peptidase(gene name synonym)|uniprotkb:Presenilin-like protein 3(gene name synonym)|uniprotkb:Intramembrane protease 1(gene name synonym)|uniprotkb:IMP1(gene name synonym)|uniprotkb:MSTP086(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_110416.1|refseq:NP_848695.1|refseq:NP_848696.1|refseq:NP_848697.1|panther:PTHR12174(orthology-group)|ensembl:ENSG00000101294.20(gene)|ensembl:ENST00000340852.9(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006465""(signal peptide processing)|go:""GO:0008233""(peptidase activity)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0033619""(membrane protein proteolysis)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0036513""(Derlin-1 retrotranslocation complex)|go:""GO:0042500""(aspartic endopeptidase activity, intramembrane cleaving)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:1904211""(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR007369(Peptidase A22B, signal peptide peptidase)|mint:Q8TCT9|reactome:R-HSA-9707587"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:DxNjJDcc+zomfXAj0TEaByKeNqc9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P05023	intact:EBI-27033185	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|ensembl:ENSP00000295598.5|intact:EBI-10963133	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR43294(orthology-group)|ensembl:ENSG00000163399.16(gene)|ensembl:ENST00000295598.10(transcript)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0005391""(""P-type sodium:potassium-exchanging transporter activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0007231""(osmosensory signaling pathway)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016791""(phosphatase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030315""(T-tubule)|go:""GO:0030424""(axon)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031090""(organelle membrane)|go:""GO:0031402""(sodium ion binding)|go:""GO:0031947""(negative regulation of glucocorticoid biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0045823""(positive regulation of heart contraction)|go:""GO:0045989""(positive regulation of striated muscle contraction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060342""(photoreceptor inner segment membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086009""(membrane repolarization)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903416""(response to glycoside)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990239""(steroid hormone binding)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|interpro:IPR050510|mint:P05023|rcsb pdb:7E1Z|rcsb pdb:7E20|rcsb pdb:7E21|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|efo:""Orphanet:521414""|efo:""Orphanet:564178"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q93050	intact:EBI-27033185	intact:EBI-2891238|uniprotkb:Q8N5G7|uniprotkb:Q9NSX0|intact:EBI-4324496|uniprotkb:B7Z3B7|ensembl:ENSP00000342951.3|ensembl:ENSP00000515539.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:vpp1_human(display_long)|uniprotkb:ATP6V0A1(gene name)|psi-mi:ATP6V0A1(display_short)|uniprotkb:ATP6N1(gene name synonym)|uniprotkb:ATP6N1A(gene name synonym)|uniprotkb:VPP1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"go:""GO:1902600""(proton transmembrane transport)|ensembl:ENSG00000033627.18(gene)|ensembl:ENST00000343619.9(transcript)|ensembl:ENST00000703901.1(transcript)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0042470""(melanosome)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051117""(ATPase binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|mint:Q93050|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:NP_001123492.1|refseq:NP_001123493.1|refseq:NP_005168.2|efo:""Orphanet:528084""|panther:PTHR11629(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:3htDhXCA9potj7i32HoA2j3Sfqw9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P05556	intact:EBI-27033185	intact:EBI-703066|intact:EBI-4289597|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5|ensembl:ENSP00000303351.3|ensembl:ENSP00000379350.2|ensembl:ENSP00000398029.2|ensembl:ENSP00000404546.3|ensembl:ENSP00000502882.1|ensembl:ENSP00000503546.1|ensembl:ENSP00000503916.1|ensembl:ENSP00000504205.1|ensembl:ENSP00000504444.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|ensembl:ENSG00000150093.20(gene)|ensembl:ENST00000302278.8(transcript)|ensembl:ENST00000396033.6(transcript)|ensembl:ENST00000417122.7(transcript)|ensembl:ENST00000437302.6(transcript)|ensembl:ENST00000677999.1(transcript)|ensembl:ENST00000678701.1(transcript)|ensembl:ENST00000678943.1(transcript)|ensembl:ENST00000678952.1(transcript)|dip:DIP-312N|ensembl:ENST00000678989.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001726""(ruffle)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002020""(protease binding)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006968""(cellular defense response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007517""(muscle organ development)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008305""(integrin complex)|go:""GO:0008354""(germ cell migration)|go:""GO:0008542""(visual learning)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010710""(regulation of collagen catabolic process)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0014704""(intercalated disc)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030175""(filopodium)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031623""(receptor internalization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0033631""(cell-cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034665""(integrin alpha1-beta1 complex)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0034667""(integrin alpha3-beta1 complex)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0034674""(integrin alpha5-beta1 complex)|go:""GO:0034675""(integrin alpha6-beta1 complex)|go:""GO:0034677""(integrin alpha7-beta1 complex)|go:""GO:0034678""(integrin alpha8-beta1 complex)|go:""GO:0034679""(integrin alpha9-beta1 complex)|go:""GO:0034680""(integrin alpha10-beta1 complex)|go:""GO:0034681""(integrin alpha11-beta1 complex)|go:""GO:0034682""(integrin alphav-beta1 complex)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043197""(dendritic spine)|go:""GO:0043235""(receptor complex)|go:""GO:0043236""(laminin binding)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045743""(positive regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048626""(myoblast fate specification)|go:""GO:0048675""(axon extension)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051951""(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0055037""(recycling endosome)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060912""(cardiac cell fate specification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097386""(glial cell projection)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150053""(cerebellar climbing fiber to Purkinje cell synapse)|go:""GO:0150103""(reactive gliosis)|go:""GO:1900748""(positive regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901979""(regulation of inward rectifier potassium channel activity)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905806""(regulation of synapse pruning)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|rcsb pdb:7CEB|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEC|rcsb pdb:7NWL|rcsb pdb:7NXD|rcsb pdb:8RPQ|rcsb pdb:9CKV|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9634597|reactome:R-HSA-9679191|reactome:R-HSA-9725554|reactome:R-HSA-9830674|reactome:R-HSA-9860927|panther:PTHR10082(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:O00767	intact:EBI-27033185	intact:EBI-2684237|uniprotkb:Q5W037|uniprotkb:B2R5U0|uniprotkb:Q96KF6|uniprotkb:Q53GR9|uniprotkb:Q9Y695|uniprotkb:Q9BS07|uniprotkb:Q16150|uniprotkb:Q6GSS4|uniprotkb:Q5W038|uniprotkb:D3DR68|ensembl:ENSP00000359380.2	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	"psi-mi:scd_human(display_long)|uniprotkb:""Delta(9)-desaturase""(gene name synonym)|uniprotkb:Fatty acid desaturase(gene name synonym)|uniprotkb:Acyl-CoA desaturase(gene name synonym)|uniprotkb:FADS5(gene name synonym)|uniprotkb:SCD1(gene name synonym)|uniprotkb:SCDOS(gene name synonym)|uniprotkb:SCD(gene name)|psi-mi:SCD(display_short)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_005054.3|ensembl:ENSG00000099194.6(gene)|ensembl:ENST00000370355.3(transcript)|go:""GO:0004768""(stearoyl-CoA 9-desaturase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006636""(unsaturated fatty acid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0032896""(palmitoyl-CoA 9-desaturase activity)|go:""GO:0070542""(response to fatty acid)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1903966""(monounsaturated fatty acid biosynthetic process)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|mint:O00767|rcsb pdb:4ZYO|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|reactome:R-HSA-9841922|panther:PTHR11351(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:GeF7PMgZb07js39m6ykSSmFuIUA9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P02786	intact:EBI-27033185	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224.4|ensembl:ENSP00000376197.3|ensembl:ENSP00000513646.1|ensembl:ENSP00000513654.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:476113""|ensembl:ENSG00000072274.14(gene)|ensembl:ENST00000360110.9(transcript)|ensembl:ENST00000392396.7(transcript)|ensembl:ENST00000698280.1(transcript)|ensembl:ENST00000698291.1(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004998""(transferrin receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010039""(response to iron ion)|go:""GO:0010042""(response to manganese ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010637""(negative regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033572""(transferrin transport)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0046688""(response to copper ion)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0072562""(blood microparticle)|go:""GO:0098944""(postsynaptic recycling endosome membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|interpro:IPR046450|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|rcsb pdb:7ZQS|rcsb pdb:8P0Z|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9725554|refseq:NP_001121620.1|refseq:NP_001300894.1|refseq:NP_001300895.1|refseq:NP_003225.2|dip:DIP-2736N|panther:PTHR10404(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P12236	intact:EBI-27033185	intact:EBI-356254|uniprotkb:Q96C49|ensembl:ENSP00000370808.5|ensembl:ENSP00000518609.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001627.2|ensembl:ENSG00000169100.14(gene)|ensembl:ENSG00000292334.1(gene)|ensembl:ENST00000381401.11(transcript)|ensembl:ENST00000711214.1(transcript)|go:""GO:0005471""(""ATP:ADP antiporter activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005744""(TIM23 mitochondrial import inner membrane translocase complex)|go:""GO:0006915""(apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0140021""(mitochondrial ADP transmembrane transport)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1990544""(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|reactome:R-HSA-9837999|panther:PTHR45635(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q9UP95	intact:EBI-27033185	intact:EBI-7244836|uniprotkb:Q13953|uniprotkb:B7ZAV0|uniprotkb:O75893|uniprotkb:O60632|intact:MINT-1191426|uniprotkb:F5H0S9|uniprotkb:B4DZ82|uniprotkb:B4DF69|uniprotkb:Q96LD5|uniprotkb:F5H3C0|uniprotkb:F5H066|uniprotkb:B4DR04|intact:EBI-11577771|ensembl:ENSP00000318557.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:s12a4_human(display_long)|uniprotkb:SLC12A4(gene name)|psi-mi:SLC12A4(display_short)|uniprotkb:KCC1(gene name synonym)|uniprotkb:Electroneutral potassium-chloride cotransporter 1(gene name synonym)|uniprotkb:Erythroid K-Cl cotransporter 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001139436.1|refseq:NP_001139433.1|refseq:NP_001139434.1|refseq:NP_005063.1|refseq:NP_001139435.1|ensembl:ENSG00000124067.17(gene)|ensembl:ENST00000316341.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0015379""(""potassium:chloride symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0045202""(synapse)|go:""GO:0055064""(chloride ion homeostasis)|go:""GO:0055075""(potassium ion homeostasis)|go:""GO:0071805""(potassium ion transmembrane transport)|go:""GO:1902476""(chloride transmembrane transport)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR000076(K-Cl co-transporter)|interpro:IPR000622(K-Cl Co-transporter, type 1)|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004842(Na-K-Cl cotransporter superfamily)|interpro:IPR018491|mint:Q9UP95|rcsb pdb:6KKR|rcsb pdb:6KKT|rcsb pdb:6KKU|rcsb pdb:7AIP|rcsb pdb:7AIQ|rcsb pdb:7AIR|rcsb pdb:7TTH|rcsb pdb:7TTI|reactome:R-HSA-426117|panther:PTHR11827(orthology-group)"	-	-	"comment:mint|comment:homomint|function:""\""Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity\"""""	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:wyweg+klinikkDDzNhNdIwomyDQ9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q13488	intact:EBI-27033185	intact:EBI-3914669|uniprotkb:Q8WVC5|uniprotkb:O75877|ensembl:ENSP00000265686.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:vpp3_human(display_long)|uniprotkb:TCIRG1(gene name)|psi-mi:TCIRG1(display_short)|uniprotkb:ATP6N1C(gene name synonym)|uniprotkb:ATP6V0A3(gene name synonym)|uniprotkb:Osteoclastic proton pump 116 kDa subunit(gene name synonym)|uniprotkb:T-cell immune regulator 1(gene name synonym)|uniprotkb:T-cell immune response cDNA7 protein(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000110719.11(gene)|ensembl:ENST00000265686.8(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0001503""(ossification)|go:""GO:0002158""(osteoclast proliferation)|go:""GO:0005634""(nucleus)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007039""(protein catabolic process in the vacuole)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010008""(endosome membrane)|go:""GO:0010155""(regulation of proton transport)|go:""GO:0010272""(response to silver ion)|go:""GO:0010467""(gene expression)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0016236""(macroautophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0021554""(optic nerve development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031529""(ruffle organization)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0033365""(protein localization to organelle)|go:""GO:0035709""(memory T cell activation)|go:""GO:0035711""(T-helper 1 cell activation)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0044691""(tooth eruption)|go:""GO:0045453""(bone resorption)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0045851""(pH reduction)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0051117""(ATPase binding)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|go:""GO:0070166""(enamel mineralization)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0090383""(phagosome acidification)|go:""GO:0097188""(dentin mineralization)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|mint:Q13488|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|refseq:NP_006010.2|refseq:NP_006044.1|refseq:XP_005273766.1|refseq:XP_011543028.1|efo:""Orphanet:1782""|efo:""Orphanet:210110""|efo:""Orphanet:486""|efo:""Orphanet:667""|panther:PTHR11629(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:WhJvt8AOkbC24bz4x4CxGyZcuow9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P29317	intact:EBI-27033185	intact:EBI-702104|uniprotkb:Q8N3Z2|ensembl:ENSP00000351209.5|uniprotkb:B5A968|intact:EBI-28989000	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:epha2_human(display_long)|uniprotkb:Tyrosine-protein kinase receptor ECK(gene name synonym)|uniprotkb:Epithelial cell kinase(gene name synonym)|uniprotkb:EPHA2(gene name)|psi-mi:EPHA2(display_short)|uniprotkb:ECK(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000142627.13(gene)|ensembl:ENST00000358432.8(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0002043""(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008288""(boss receptor activity)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009986""(cell surface)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0014028""(notochord formation)|go:""GO:0016477""(cell migration)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019838""(growth factor binding)|go:""GO:0021915""(neural tube development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0043235""(receptor complex)|go:""GO:0043535""(regulation of blood vessel endothelial cell migration)|go:""GO:0045296""(cadherin binding)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0046058""(cAMP metabolic process)|go:""GO:0046849""(bone remodeling)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048320""(axial mesoderm formation)|go:""GO:0048870""(cell motility)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0060035""(notochord cell development)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0060444""(branching involved in mammary gland duct morphogenesis)|go:""GO:0070160""(tight junction)|go:""GO:0070309""(lens fiber cell morphogenesis)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070848""(response to growth factor)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1901491""(negative regulation of lymphangiogenesis)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1904238""(pericyte cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034263|interpro:IPR036116|interpro:IPR050449|mint:P29317|rcsb pdb:1MQB|rcsb pdb:2E8N|rcsb pdb:2K9Y|rcsb pdb:2KSO|rcsb pdb:2X10|rcsb pdb:2X11|rcsb pdb:3C8X|rcsb pdb:3CZU|rcsb pdb:3FL7|rcsb pdb:3HEI|rcsb pdb:3HPN|rcsb pdb:3KKA|rcsb pdb:3MBW|rcsb pdb:3MX0|rcsb pdb:3SKJ|rcsb pdb:4P2K|rcsb pdb:4PDO|rcsb pdb:4TRL|rcsb pdb:5EK7|rcsb pdb:5I9U|rcsb pdb:5I9V|rcsb pdb:5I9W|rcsb pdb:5I9X|rcsb pdb:5I9Y|rcsb pdb:5I9Z|rcsb pdb:5IA0|rcsb pdb:5IA1|rcsb pdb:5IA2|rcsb pdb:5IA3|rcsb pdb:5IA4|rcsb pdb:5IA5|rcsb pdb:5NJZ|rcsb pdb:5NK0|rcsb pdb:5NK1|rcsb pdb:5NK2|rcsb pdb:5NK3|rcsb pdb:5NK4|rcsb pdb:5NK5|rcsb pdb:5NK6|rcsb pdb:5NK7|rcsb pdb:5NK8|rcsb pdb:5NK9|rcsb pdb:5NKA|rcsb pdb:5NKB|rcsb pdb:5NKC|rcsb pdb:5NKD|rcsb pdb:5NKE|rcsb pdb:5NKF|rcsb pdb:5NKG|rcsb pdb:5NKH|rcsb pdb:5NKI|rcsb pdb:5NZ9|rcsb pdb:6B9L|rcsb pdb:6F7M|rcsb pdb:6F7N|rcsb pdb:6FNF|rcsb pdb:6NK1|rcsb pdb:6FNG|rcsb pdb:6FNH|rcsb pdb:6HES|rcsb pdb:6HET|rcsb pdb:6HEU|rcsb pdb:6HEV|rcsb pdb:6HEW|rcsb pdb:6HEX|rcsb pdb:6HEY|rcsb pdb:6NJZ|rcsb pdb:6NK0|rcsb pdb:6NK2|rcsb pdb:6NKP|rcsb pdb:6Q7B|rcsb pdb:6Q7C|rcsb pdb:6Q7D|rcsb pdb:6Q7E|rcsb pdb:6Q7F|rcsb pdb:6Q7G|rcsb pdb:6RW2|rcsb pdb:7B7N|rcsb pdb:7CZE|rcsb pdb:7CZF|rcsb pdb:7KJA|rcsb pdb:7KJB|rcsb pdb:7KJC|rcsb pdb:8BIN|rcsb pdb:8BIO|rcsb pdb:8BK0|rcsb pdb:8BM8|rcsb pdb:8BOC|rcsb pdb:8BOD|rcsb pdb:8BOF|rcsb pdb:8BOG|rcsb pdb:8BOH|rcsb pdb:8BOI|rcsb pdb:8BOK|rcsb pdb:8BOM|rcsb pdb:8QQY|rcsb pdb:8T9B|rcsb pdb:8TRS|rcsb pdb:8TRT|rcsb pdb:8TRV|rcsb pdb:8TV1|rcsb pdb:8TV5|rcsb pdb:8XPV|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_004422.2|efo:""Orphanet:441447""|efo:""Orphanet:98991""|efo:""Orphanet:98993""|efo:""Orphanet:98994""|dip:DIP-96N|panther:PTHR24416(orthology-group)|ensembl:ENSP00000351209.5"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:9VFikLd4ftRmEyBpY0JHdpHINT09606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P52292	intact:EBI-27033185	intact:EBI-349938|uniprotkb:Q9BRU5|intact:EBI-28977049|uniprotkb:B9EJD6|uniprotkb:Q53YE3|ensembl:ENSP00000332455.3|ensembl:ENSP00000438483.2|ensembl:ENSP00000462331.2|ensembl:ENSP00000463602.2|ensembl:ENSP00000504655.1|ensembl:ENSP00000504685.1|intact:EBI-9377406|uniprotkb:Q6NVW7	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033770|imex:IM-29092-103	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENSG00000182481.10(gene)|ensembl:ENST00000330459.8(transcript)|ensembl:ENST00000537025.6(transcript)|ensembl:ENST00000579754.2(transcript)|ensembl:ENST00000584026.6(transcript)|ensembl:ENST00000677086.1(transcript)|ensembl:ENST00000679078.1(transcript)|go:""GO:0000018""(regulation of DNA recombination)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006259""(DNA metabolic process)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0042564""(NLS-dependent protein nuclear import complex)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043657""(host cell)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0075506""(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:""GO:1903902""(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7CRU|rcsb pdb:7N8J|rcsb pdb:7N9H|rcsb pdb:8FZK|rcsb pdb:8GCN|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|reactome:R-HSA-9692916|reactome:R-HSA-9705671|dip:DIP-6205N|panther:PTHR23316(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606	intact-crc:D6AFDA2A214A06B1|rigid:TH+fX1KvMZcXatZbcevgpkpzmi4	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:P40937	intact:EBI-11477981	intact:EBI-712376|ensembl:ENSP00000408295.2|uniprotkb:A8MZ62|uniprotkb:B3KSX8	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:rfc5_human(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033817|imex:IM-29092-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_031396.1|refseq:NP_853556.2|refseq:XP_011536945.1|refseq:XP_011536947.1|ensembl:ENSG00000111445.14(gene)|ensembl:ENST00000454402.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005663""(DNA replication factor C complex)|go:""GO:0006260""(DNA replication)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031390""(Ctf18 RFC-like complex)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:1900264""(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|interpro:IPR047854|interpro:IPR050238|mint:P40937|rcsb pdb:6VVO|rcsb pdb:7Z6H|rcsb pdb:8UI7|rcsb pdb:8UI8|rcsb pdb:8UI9|rcsb pdb:8UII|rcsb pdb:8UMT|rcsb pdb:8UMU|rcsb pdb:8UMV|rcsb pdb:8UMW|rcsb pdb:8UMY|rcsb pdb:8UN0|rcsb pdb:8UNJ|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-9709570|refseq:NP_001123584.1|refseq:NP_001123585.1|dip:DIP-36433N|panther:PTHR11669(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/28	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:F7oadHDk6fkhHn+3rDF9K2JHSl49606	intact-crc:B9CE5F14487A8C95|rigid:suQEek3tPsNTryc456JlKzLb0zI	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q9P2J5	intact:EBI-11477981	intact:EBI-356077|uniprotkb:Q9NSE1|uniprotkb:A7E266|ensembl:ENSP00000377954.2|uniprotkb:A2RRR4|uniprotkb:B4DJ10|uniprotkb:Q2TU79	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:sylc_human(display_long)|uniprotkb:LARS1(gene name)|psi-mi:LARS1(display_short)|uniprotkb:KIAA1352(gene name synonym)|uniprotkb:LARS(gene name synonym)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033817|imex:IM-29092-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"efo:""Orphanet:370088""|ensembl:ENSG00000133706.20(gene)|ensembl:ENST00000394434.7(transcript)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004819""(glutamine-tRNA ligase activity)|go:""GO:0004823""(leucine-tRNA ligase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006418""(tRNA aminoacylation for protein translation)|go:""GO:0006425""(glutaminyl-tRNA aminoacylation)|go:""GO:0006429""(leucyl-tRNA aminoacylation)|go:""GO:0008361""(regulation of cell size)|go:""GO:0012505""(endomembrane system)|go:""GO:0016604""(nuclear body)|go:""GO:0017101""(aminoacyl-tRNA synthetase multienzyme complex)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990253""(cellular response to leucine starvation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR004493(Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR054509|mint:Q9P2J5|rcsb pdb:2WFD|rcsb pdb:6KID|rcsb pdb:6KIE|rcsb pdb:6KQY|rcsb pdb:6KR7|rcsb pdb:6LPF|rcsb pdb:6LR6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-9856649|refseq:NP_001304893.1|refseq:NP_001304894.1|refseq:NP_057544.2|refseq:NP_064502.9|refseq:XP_011535958.1|panther:PTHR45794(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/28	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:nlK4kRCik2LLC3VNl0sryrLLnqA9606	intact-crc:B9CE5F14487A8C95|rigid:suQEek3tPsNTryc456JlKzLb0zI	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q8WWI1	intact:EBI-11477981	intact:EBI-350367|uniprotkb:O15462|uniprotkb:O95346|uniprotkb:Q9UKC1|uniprotkb:Q9UQM5|uniprotkb:Q9Y6A7|uniprotkb:Q5TBK6|uniprotkb:E9PLH4	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:lmo7_human(display_long)|uniprotkb:LMO7(gene name)|psi-mi:LMO7(display_short)|uniprotkb:FBX20(gene name synonym)|uniprotkb:FBXO20(gene name synonym)|uniprotkb:KIAA0858(gene name synonym)|uniprotkb:F-box only protein 20(gene name synonym)|uniprotkb:LOMP(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033817|imex:IM-29092-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_001293009.1|refseq:NP_001317512.1|refseq:NP_005349.3|refseq:NP_056667.2|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0009986""(cell surface)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0023051""(regulation of signaling)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003096(SM22/calponin)|interpro:IPR029978|interpro:IPR031865|interpro:IPR036034|interpro:IPR036872|rcsb pdb:2EAQ|reactome:R-HSA-8951664|reactome:R-HSA-9725370|reactome:R-HSA-983168|mint:Q8WWI1|dip:DIP-33107N|panther:PTHR46767(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/28	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:d8c3oZaqaloIUBqxgvpNI3PP2fU9606	intact-crc:B9CE5F14487A8C95|rigid:suQEek3tPsNTryc456JlKzLb0zI	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:P59998	intact:EBI-11477981	intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|uniprotkb:F6TTL5|ensembl:ENSP00000380431.2	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033817|imex:IM-29092-41	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"efo:""Orphanet:662762""|ensembl:ENSG00000241553.13(gene)|ensembl:ENST00000397261.8(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0019899""(enzyme binding)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042995""(cell projection)|go:""GO:0045010""(actin nucleation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|refseq:NP_001185709.1|refseq:NP_005709.1|dip:DIP-33188N|panther:PTHR22629(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/28	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606	intact-crc:B9CE5F14487A8C95|rigid:suQEek3tPsNTryc456JlKzLb0zI	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1M5	uniprotkb:P61026	intact:EBI-11477991	intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710.4	psi-mi:a0a0f6b1m5_salt1(display_long)|uniprotkb:sifB(gene name)|psi-mi:sifB(display_short)|uniprotkb:STM14_1940(locus name)	psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033901|imex:IM-29092-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001122926.1|interpro:IPR010637(Sif)|mint:A0A0F6B1M5	"refseq:NP_057215.3|ensembl:ENSG00000084733.11(gene)|ensembl:ENST00000264710.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0007409""(axonogenesis)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0019003""(GDP binding)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0031489""(myosin V binding)|go:""GO:0032593""(insulin-responsive compartment)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045200""(establishment of neuroblast polarity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070382""(exocytic vesicle)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0097051""(establishment of protein localization to endoplasmic reticulum membrane)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0099503""(secretory vesicle)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:P61026|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/27	rogid:T51GYRB8ilSWwo+glNdBEDDBNZE588858	rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606	intact-crc:AE2927DB26A3B5A6|rigid:i5t7iEkntVIdSUb1cqbn2J6Qnyk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1M5	uniprotkb:P51153	intact:EBI-11477991	intact:EBI-1780121|ensembl:ENSP00000357564.3|uniprotkb:Q5U0A6|uniprotkb:Q6GPG6|uniprotkb:Q96GU4|uniprotkb:A8K6B5|uniprotkb:D3DV67	psi-mi:a0a0f6b1m5_salt1(display_long)|uniprotkb:sifB(gene name)|psi-mi:sifB(display_short)|uniprotkb:STM14_1940(locus name)	psi-mi:rab13_human(display_long)|uniprotkb:RAB13(gene name)|psi-mi:RAB13(display_short)|uniprotkb:GIG4(orf name)|uniprotkb:Cell growth-inhibiting gene 4 protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033901|imex:IM-29092-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001122926.1|interpro:IPR010637(Sif)|mint:A0A0F6B1M5	"ensembl:ENSG00000143545.10(gene)|ensembl:ENST00000368575.5(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005768""(endosome)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0010737""(protein kinase A signaling)|go:""GO:0015031""(protein transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031175""(neuron projection development)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032593""(insulin-responsive compartment)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035767""(endothelial cell chemotaxis)|go:""GO:0043005""(neuron projection)|go:""GO:0044795""(trans-Golgi network to recycling endosome transport)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0097368""(establishment of Sertoli cell barrier)|go:""GO:1902463""(protein localization to cell leading edge)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:P51153|reactome:R-HSA-1445148|reactome:R-HSA-8873719|reactome:R-HSA-8876198|refseq:NP_002861.1|refseq:NP_001258967.1|dip:DIP-40268N|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/27	rogid:T51GYRB8ilSWwo+glNdBEDDBNZE588858	rogid:XopTW/3AqUPyTi66Nf0HYlkD6Fw9606	intact-crc:AE2927DB26A3B5A6|rigid:i5t7iEkntVIdSUb1cqbn2J6Qnyk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61586	intact:EBI-10760263	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9Y6E2	intact:EBI-10760263	intact:EBI-1051021|uniprotkb:Q9H3F7|uniprotkb:Q3B779|uniprotkb:A4D123|uniprotkb:Q96JW5|ensembl:ENSP00000258761.3|ensembl:ENSP00000397249.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:5mp1_human(display_long)|uniprotkb:Basic leucine zipper and W2 domain-containing protein 2(gene name synonym)|uniprotkb:5MP1(gene name synonym)|uniprotkb:HSPC028(orf name)|uniprotkb:MSTP017(orf name)|uniprotkb:BZW2(gene name)|psi-mi:BZW2(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001153239.1|refseq:NP_054757.1|refseq:XP_006715769.1|refseq:XP_006715770.1|refseq:XP_006715771.1|ensembl:ENSG00000136261.16(gene)|ensembl:ENST00000258761.8(transcript)|ensembl:ENST00000433922.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016020""(membrane)|go:""GO:0045296""(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|interpro:IPR051245|mint:Q9Y6E2|panther:PTHR14208(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:+z22Ykb6e3IM9zk51m6tjuhiEcU9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P55060	intact:EBI-10760263	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|ensembl:ENSP00000262982.2|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000124207.17(gene)|ensembl:ENST00000262982.3(transcript)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060|refseq:NP_001307.2|refseq:NP_001243064.1|refseq:XP_011526901.1|dip:DIP-32573N|panther:PTHR10997(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q5VYK3	intact:EBI-10760263	intact:EBI-521451|uniprotkb:A0A804HJA4|uniprotkb:B3KXF2|uniprotkb:O15074|uniprotkb:Q8WU82	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:ecm29_human(display_long)|uniprotkb:ECPAS(gene name)|psi-mi:ECPAS(display_short)|uniprotkb:ECM29(gene name synonym)|uniprotkb:Ecm29 proteasome adapter and scaffold(gene name synonym)|uniprotkb:KIAA0368(gene name synonym)|uniprotkb:Proteasome-associated protein ECM29 homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:XP_005251908.1|refseq:XP_005251909.1|refseq:XP_005251910.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024372|mint:Q5VYK3|refseq:XP_005251907.1|go:""GO:0000502""(proteasome complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005813""(centrosome)|go:""GO:0016020""(membrane)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0036503""(ERAD pathway)|go:""GO:0043248""(proteasome assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070628""(proteasome binding)|panther:PTHR23346(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:lBqnwI2OO2aNvK1kjEpYOGK4oUI9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P42345	intact:EBI-10760263	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|intact:EBI-28989074|ensembl:ENSP00000354558.4|ensembl:ENSP00000515200.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)|uniprotkb:Tyrosine-protein kinase mTOR(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:269001""|efo:""Orphanet:269008""|efo:""Orphanet:457485""|efo:""Orphanet:99802""|ensembl:ENSG00000198793.14(gene)|ensembl:ENST00000361445.9(transcript)|ensembl:ENST00000703143.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000822""(inositol hexakisphosphate binding)|go:""GO:0001002""(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:""GO:0001003""(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:""GO:0001006""(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:""GO:0001156""(TFIIIC-class transcription factor complex binding)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002296""(T-helper 1 cell lineage commitment)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003179""(heart valve morphogenesis)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006112""(energy reserve metabolic process)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007281""(germ cell development)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009408""(response to heat)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010831""(positive regulation of myotube differentiation)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0016605""(PML body)|go:""GO:0019228""(neuronal action potential)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030425""(dendrite)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031529""(ruffle organization)|go:""GO:0031641""(regulation of myelination)|go:""GO:0031648""(protein destabilization)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0031670""(cellular response to nutrient)|go:""GO:0031929""(TOR signaling)|go:""GO:0031931""(TORC1 complex)|go:""GO:0031932""(TORC2 complex)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0038203""(TORC2 signaling)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043200""(response to amino acid)|go:""GO:0043276""(anoikis)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045670""(regulation of osteoclast differentiation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0045945""(positive regulation of transcription by RNA polymerase III)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046889""(positive regulation of lipid biosynthetic process)|go:""GO:0048266""(behavioral response to pain)|go:""GO:0048511""(rhythmic process)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050882""(voluntary musculoskeletal movement)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055013""(cardiac muscle cell development)|go:""GO:0060048""(cardiac muscle contraction)|go:""GO:0061431""(cellular response to methionine)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071470""(cellular response to osmotic stress)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090559""(regulation of membrane permeability)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1903691""(positive regulation of wound healing, spreading of epidermal cells)|go:""GO:1904059""(regulation of locomotor rhythm)|go:""GO:1904690""(positive regulation of cytoplasmic translational initiation)|go:""GO:1905671""(regulation of lysosome organization)|go:""GO:1905672""(negative regulation of lysosome organization)|go:""GO:1905857""(positive regulation of pentose-phosphate shunt)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990253""(cellular response to leucine starvation)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|interpro:IPR050517|mint:P42345|rcsb pdb:1AUE|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|rcsb pdb:7EPD|rcsb pdb:7OWG|rcsb pdb:7PE7|rcsb pdb:7PE8|rcsb pdb:7PE9|rcsb pdb:7PEA|rcsb pdb:7PEB|rcsb pdb:7PEC|rcsb pdb:7TZO|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8ER6|rcsb pdb:8ER7|rcsb pdb:8ERA|rcsb pdb:8PPZ|rcsb pdb:8RCH|rcsb pdb:8RCK|rcsb pdb:8RCN|rcsb pdb:9F44|rcsb pdb:9F45|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|reactome:R-HSA-9856530|refseq:NP_004949.1|refseq:XP_005263495.1|dip:DIP-790N|panther:PTHR11139(orthology-group)|ensembl:ENSP00000354558.4|ensembl:ENSP00000515200.2"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O15427	intact:EBI-10760263	intact:EBI-7600166|uniprotkb:Q2M1P8|intact:MINT-4526381|uniprotkb:B3KXG8|ensembl:ENSP00000376150.1|ensembl:ENSP00000376152.1|ensembl:ENSP00000462405.1|ensembl:ENSP00000463978.1|ensembl:ENSP00000464112.2|ensembl:ENSP00000464625.2|ensembl:ENSP00000482013.1|ensembl:ENSP00000483212.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:mot4_human(display_long)|uniprotkb:SLC16A3(gene name)|psi-mi:SLC16A3(display_short)|uniprotkb:MCT4(gene name synonym)|uniprotkb:Solute carrier family 16 member 3(gene name synonym)|uniprotkb:MCT3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:XP_011521909.1|refseq:NP_004198.1|refseq:NP_001193879.1|refseq:NP_001193880.1|refseq:NP_001035888.1|refseq:NP_001035887.1|refseq:NP_001193881.1|ensembl:ENSG00000141526.18(gene)|ensembl:ENST00000392339.6(transcript)|ensembl:ENST00000392341.6(transcript)|ensembl:ENST00000580189.6(transcript)|ensembl:ENST00000581287.5(transcript)|ensembl:ENST00000582743.6(transcript)|ensembl:ENST00000584689.6(transcript)|ensembl:ENST00000617373.5(transcript)|ensembl:ENST00000619321.2(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0008028""(monocarboxylic acid transmembrane transporter activity)|go:""GO:0015650""(""lactate:proton symporter activity"")|go:""GO:0015718""(monocarboxylic acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035873""(lactate transmembrane transport)|go:""GO:0042867""(pyruvate catabolic process)|go:""GO:0050833""(pyruvate transmembrane transporter activity)|go:""GO:1901475""(pyruvate transmembrane transport)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|interpro:IPR050327|mint:O15427|reactome:R-HSA-210991|reactome:R-HSA-433692|panther:PTHR11360(orthology-group)"	-	-	comment:mint|function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate|comment:homomint	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Ipq+K2KMGnogWD9ouLcBjZ53ICs9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q6P1A2	intact:EBI-10760263	intact:EBI-11337923|uniprotkb:Q92980|uniprotkb:B7Z3N3|uniprotkb:Q9BW40|uniprotkb:B2RDH0|uniprotkb:Q7KZS1|ensembl:ENSP00000261407.4	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:mboa5_human(display_long)|uniprotkb:LPCAT3(gene name)|psi-mi:LPCAT3(display_short)|uniprotkb:1-acylglycerophosphocholine O-acyltransferase(gene name synonym)|uniprotkb:1-acylglycerophosphoserine O-acyltransferase(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 3(gene name synonym)|uniprotkb:Lysophosphatidylserine acyltransferase(gene name synonym)|uniprotkb:MBOAT5(gene name synonym)|uniprotkb:Membrane-bound O-acyltransferase domain-containing protein 5(gene name synonym)|uniprotkb:OACT5(gene name synonym)|uniprotkb:1-acylglycerophosphoethanolamine O-acyltransferase(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_005759.4|ensembl:ENSG00000111684.11(gene)|ensembl:ENST00000261407.9(transcript)|go:""GO:0003841""(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006656""(phosphatidylcholine biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0030258""(lipid modification)|go:""GO:0034378""(chylomicron assembly)|go:""GO:0034379""(very-low-density lipoprotein particle assembly)|go:""GO:0036150""(phosphatidylserine acyl-chain remodeling)|go:""GO:0036151""(phosphatidylcholine acyl-chain remodeling)|go:""GO:0036152""(phosphatidylethanolamine acyl-chain remodeling)|go:""GO:0036335""(intestinal stem cell homeostasis)|go:""GO:0045540""(regulation of cholesterol biosynthetic process)|go:""GO:0045797""(positive regulation of intestinal cholesterol absorption)|go:""GO:0047144""(2-acylglycerol-3-phosphate O-acyltransferase activity)|go:""GO:0047184""(1-acylglycerophosphocholine O-acyltransferase activity)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0071617""(lysophospholipid acyltransferase activity)|go:""GO:0090158""(endoplasmic reticulum membrane organization)|go:""GO:0106262""(1-acylglycerophosphoethanolamine O-acyltransferase activity)|go:""GO:0106263""(1-acylglycerophosphoserine O-acyltransferase activity)|go:""GO:1903573""(negative regulation of response to endoplasmic reticulum stress)|go:""GO:1905885""(positive regulation of triglyceride transport)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR049941|mint:Q6P1A2|reactome:R-HSA-1482788|reactome:R-HSA-1482801|reactome:R-HSA-1482839|panther:PTHR13906(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:A1i5tPhd5ToMitkCN/Hpyzpxuwk9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q99865	intact:EBI-10760263	intact:EBI-25483168|ensembl:ENSP00000364041.3|ensembl:ENSP00000364043.1|uniprotkb:O75650|uniprotkb:Q6IPW2|uniprotkb:Q9UJJ0	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:spi2a_human(display_long)|uniprotkb:SPIN2A(gene name)|psi-mi:SPIN2A(display_short)|uniprotkb:DXF34(gene name synonym)|uniprotkb:SPIN2(gene name synonym)|uniprotkb:Protein DXF34(gene name synonym)|uniprotkb:Spindlin-like protein 2A(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000147059.9(gene)|ensembl:ENST00000374906.4(transcript)|ensembl:ENST00000374908.1(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007276""(gamete generation)|go:""GO:0035064""(methylated histone binding)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR042567|mint:Q99865|refseq:NP_061876.3|refseq:XP_005262073.3|refseq:XP_005262074.3|refseq:XP_005262076.1|refseq:XP_016885087.1|panther:PTHR10405(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:fd0LwjY2zf4PeaRNs2aUbx8wJG89606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q8WUX1	intact:EBI-10760263	intact:EBI-2801419|uniprotkb:Q6PIW9|uniprotkb:Q8WYU2|uniprotkb:B7WPJ9|uniprotkb:B3KT20|uniprotkb:B5MDE6|uniprotkb:Q96PQ4|ensembl:ENSP00000471683.1|ensembl:ENSP00000481291.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:s38a5_human(display_long)|uniprotkb:JM24(gene name synonym)|uniprotkb:SN2(gene name synonym)|uniprotkb:SNAT5(gene name synonym)|uniprotkb:Solute carrier family 38 member 5(gene name synonym)|uniprotkb:System N transporter 2(gene name synonym)|uniprotkb:PP7194(orf name)|uniprotkb:SLC38A5(gene name)|psi-mi:SLC38A5(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:XP_016885450.1|refseq:NP_277053.2|ensembl:ENSG00000017483.16(gene)|ensembl:ENST00000595796.5(transcript)|ensembl:ENST00000620913.5(transcript)|go:""GO:0005290""(L-histidine transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0006868""(glutamine transport)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015182""(L-asparagine transmembrane transporter activity)|go:""GO:0015186""(L-glutamine transmembrane transporter activity)|go:""GO:0015187""(glycine transmembrane transporter activity)|go:""GO:0015194""(L-serine transmembrane transporter activity)|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0015816""(glycine transport)|go:""GO:0015825""(L-serine transport)|go:""GO:0022858""(alanine transmembrane transporter activity)|go:""GO:0032329""(serine transport)|go:""GO:0032973""(amino acid export across plasma membrane)|go:""GO:0089709""(L-histidine transmembrane transport)|go:""GO:0089718""(amino acid import across plasma membrane)|go:""GO:0140830""(""L-glutamine, sodium:proton antiporter activity"")|go:""GO:0140893""(""neutral amino acid, sodium:proton antiporter activity"")|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1903713""(asparagine transmembrane transport)|go:""GO:1903803""(L-glutamine import across plasma membrane)|go:""GO:1903812""(L-serine import across plasma membrane)|go:""GO:1904557""(L-alanine transmembrane transport)|interpro:IPR013057(Amino acid transporter, transmembrane)|mint:Q8WUX1|reactome:R-HSA-352230|panther:PTHR22950(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:NfYkXIX2MWwchnZA5m66xB5p/8E9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9H2H9	intact:EBI-10760263	intact:EBI-9978441|uniprotkb:Q8NC61|uniprotkb:Q8NCF8|uniprotkb:Q96JX2|uniprotkb:Q9H2Q2|ensembl:ENSP00000381634.4|ensembl:ENSP00000398142.1|ensembl:ENSP00000447853.1|ensembl:ENSP00000449607.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:s38a1_human(display_long)|uniprotkb:SLC38A1(gene name)|psi-mi:SLC38A1(display_short)|uniprotkb:ATA1(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:SAT1(gene name synonym)|uniprotkb:SNAT1(gene name synonym)|uniprotkb:Amino acid transporter A1(gene name synonym)|uniprotkb:N-system amino acid transporter 2(gene name synonym)|uniprotkb:Solute carrier family 38 member 1(gene name synonym)|uniprotkb:System A amino acid transporter 1(gene name synonym)|uniprotkb:System N amino acid transporter 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001070952.1|refseq:NP_001265316.1|refseq:NP_001265317.1|refseq:NP_001265318.1|refseq:NP_109599.3|ensembl:ENSG00000111371.16(gene)|ensembl:ENST00000398637.10(transcript)|ensembl:ENST00000439706.5(transcript)|ensembl:ENST00000546893.5(transcript)|ensembl:ENST00000549049.5(transcript)|go:""GO:0001504""(neurotransmitter uptake)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005283""(""amino acid:sodium symporter activity"")|go:""GO:0005295""(""neutral L-amino acid:sodium symporter activity"")|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0006865""(amino acid transport)|go:""GO:0006868""(glutamine transport)|go:""GO:0007565""(female pregnancy)|go:""GO:0009449""(gamma-aminobutyric acid biosynthetic process)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015186""(L-glutamine transmembrane transporter activity)|go:""GO:0015375""(""glycine:sodium symporter activity"")|go:""GO:0015655""(""alanine:sodium symporter activity"")|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0032228""(regulation of synaptic transmission, GABAergic)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043090""(amino acid import)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098591""(external side of apical plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901036""(positive regulation of L-glutamine import across plasma membrane)|go:""GO:1902475""(L-alpha-amino acid transmembrane transport)|interpro:IPR013057(Amino acid transporter, transmembrane)|mint:Q9H2H9|reactome:R-HSA-210455|reactome:R-HSA-352230|panther:PTHR22950(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:bywv401DbQBHRZvcPc8o8mp8nfE9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q6DD88	intact:EBI-10760263	intact:EBI-6165882|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1|ensembl:ENSP00000381844.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000184743.13(gene)|ensembl:ENST00000398868.8(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0098826""(endoplasmic reticulum tubular network membrane)|go:""GO:1903373""(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|refseq:NP_001276977.1|refseq:NP_056274.3|efo:""Orphanet:36386""|panther:PTHR10751(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P08195	intact:EBI-10760263	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q96G23	intact:EBI-10760263	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688.6|ensembl:ENSP00000357950.5	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418.20(gene)|ensembl:ENST00000271688.10(transcript)|ensembl:ENST00000368954.10(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0030148""(sphingolipid biosynthetic process)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0046513""(ceramide biosynthetic process)|go:""GO:0048681""(negative regulation of axon regeneration)|go:""GO:0050291""(sphingosine N-acyltransferase activity)|go:""GO:1900148""(negative regulation of Schwann cell migration)|go:""GO:1905045""(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|panther:PTHR12560(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9NZM1	intact:EBI-10760263	intact:EBI-1994363|ensembl:ENSP00000352208.4|uniprotkb:Q5VWW2|uniprotkb:Q5VWW3|uniprotkb:Q5VWW4|uniprotkb:Q5VWW5|uniprotkb:Q7Z642|uniprotkb:Q8IWH0|uniprotkb:Q9HBU3|uniprotkb:Q9NZM0|uniprotkb:Q9ULL3|uniprotkb:Q9Y4U4|uniprotkb:B3KQN5	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:myof_human(display_long)|uniprotkb:MYOF(gene name)|psi-mi:MYOF(display_short)|uniprotkb:KIAA1207(gene name synonym)|uniprotkb:FER1L3(gene name synonym)|uniprotkb:Fer-1-like protein 3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000138119.17(gene)|ensembl:ENST00000359263.9(transcript)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0006936""(muscle contraction)|go:""GO:0008015""(blood circulation)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046928""(regulation of neurotransmitter secretion)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|interpro:IPR055072|mint:Q9NZM1|rcsb pdb:2DMH|rcsb pdb:2K2O|rcsb pdb:6EEL|refseq:NP_038479.1|refseq:NP_579899.1|panther:PTHR45911(orthology-group)|efo:""Orphanet:599418"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:YbWzqcootZO0/w6OLRqxZEEAu9U9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P18031	intact:EBI-10760263	intact:EBI-968788|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4|ensembl:ENSP00000360683.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N|ensembl:ENSG00000196396.10(gene)|ensembl:ENST00000371621.5(transcript)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0003723""(RNA binding)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0009968""(negative regulation of signal transduction)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030162""(regulation of proteolysis)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031904""(endosome lumen)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033157""(regulation of intracellular protein transport)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035791""(platelet-derived growth factor receptor-beta signaling pathway)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045296""(cadherin binding)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071732""(cellular response to nitric oxide)|go:""GO:0097443""(sorting endosome)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903896""(positive regulation of IRE1-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904753""(negative regulation of vascular associated smooth muscle cell migration)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990264""(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:""GO:2000353""(positive regulation of endothelial cell apoptotic process)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1AAX|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2F6Z|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:2NT7|rcsb pdb:2NTA|rcsb pdb:2QBP|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2QBS|rcsb pdb:2VEU|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2ZMM|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:3EB1|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QDV|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:6OMY|rcsb pdb:6PFW|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:6XE8|rcsb pdb:6XEF|rcsb pdb:6XEA|rcsb pdb:6XED|rcsb pdb:6XEE|rcsb pdb:6XEG|rcsb pdb:7FQM|rcsb pdb:7FQN|rcsb pdb:7FQO|rcsb pdb:7FQP|rcsb pdb:7FQQ|rcsb pdb:7FQR|rcsb pdb:7FQS|rcsb pdb:7FQT|rcsb pdb:7FQU|rcsb pdb:7FQV|rcsb pdb:7FQW|rcsb pdb:7FQX|rcsb pdb:7FQY|rcsb pdb:7FQZ|rcsb pdb:7FRE|rcsb pdb:7FRF|rcsb pdb:7FRG|rcsb pdb:7FRH|rcsb pdb:7FRI|rcsb pdb:7FRJ|rcsb pdb:7FRK|rcsb pdb:7FRL|rcsb pdb:7FRM|rcsb pdb:7FRN|rcsb pdb:7FRO|rcsb pdb:7FRP|rcsb pdb:7FRQ|rcsb pdb:7FRR|rcsb pdb:7FRS|rcsb pdb:7FRT|rcsb pdb:7FRU|rcsb pdb:7GS7|rcsb pdb:7GS8|rcsb pdb:7GS9|rcsb pdb:7GSA|rcsb pdb:7GSB|rcsb pdb:7GSC|rcsb pdb:7GSD|rcsb pdb:7GSE|rcsb pdb:7GSF|rcsb pdb:7GSG|rcsb pdb:7GSH|rcsb pdb:7GSI|rcsb pdb:7GSJ|rcsb pdb:7GSK|rcsb pdb:7GSL|rcsb pdb:7GSM|rcsb pdb:7GSN|rcsb pdb:7GSO|rcsb pdb:7GSQ|rcsb pdb:7GSR|rcsb pdb:7GST|rcsb pdb:7GSU|rcsb pdb:7GSV|rcsb pdb:7GSW|rcsb pdb:7GSX|rcsb pdb:7GSY|rcsb pdb:7GSZ|rcsb pdb:7GT0|rcsb pdb:7GT1|rcsb pdb:7GT2|rcsb pdb:7GT3|rcsb pdb:7GT4|rcsb pdb:7GT5|rcsb pdb:7GTI|rcsb pdb:7GT6|rcsb pdb:7GT7|rcsb pdb:7GT8|rcsb pdb:7GT9|rcsb pdb:7GTA|rcsb pdb:7GTB|rcsb pdb:7GTC|rcsb pdb:7GTD|rcsb pdb:7GTE|rcsb pdb:7GTF|rcsb pdb:7GTG|rcsb pdb:7GTH|rcsb pdb:7GTJ|rcsb pdb:7GTK|rcsb pdb:7GTL|rcsb pdb:7GTM|rcsb pdb:7GTN|rcsb pdb:7GTO|rcsb pdb:7GTP|rcsb pdb:7GTQ|rcsb pdb:7GTR|rcsb pdb:7GTS|rcsb pdb:7GTT|rcsb pdb:7GTU|rcsb pdb:7GTV|rcsb pdb:7GTW|rcsb pdb:7GTX|rcsb pdb:7GTY|rcsb pdb:7GTZ|rcsb pdb:7GU0|rcsb pdb:7GU1|rcsb pdb:7GU2|rcsb pdb:7GU3|rcsb pdb:7GU4|rcsb pdb:7GU5|rcsb pdb:7GU6|rcsb pdb:7GU7|rcsb pdb:7GU8|rcsb pdb:7GU9|rcsb pdb:7GUA|rcsb pdb:7GUB|rcsb pdb:7GUC|rcsb pdb:7KEN|rcsb pdb:7KEY|rcsb pdb:7KLX|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MKZ|rcsb pdb:7MM1|rcsb pdb:7MN7|rcsb pdb:7MN9|rcsb pdb:7MNA|rcsb pdb:7MNB|rcsb pdb:7MNC|rcsb pdb:7MND|rcsb pdb:7MNE|rcsb pdb:7MNF|rcsb pdb:7MOU|rcsb pdb:7MOV|rcsb pdb:7MOW|rcsb pdb:7RIN|rcsb pdb:7S4F|rcsb pdb:8DU7|rcsb pdb:8EXI|rcsb pdb:8EXJ|rcsb pdb:8EXK|rcsb pdb:8EXM|rcsb pdb:8EXN|rcsb pdb:8EYA|rcsb pdb:8EYB|rcsb pdb:8EYC|rcsb pdb:8F88|rcsb pdb:8G65|rcsb pdb:8G67|rcsb pdb:8G68|rcsb pdb:8G69|rcsb pdb:8G6A|rcsb pdb:8SKL|rcsb pdb:8U1E|rcsb pdb:8XOY|rcsb pdb:9C66|rcsb pdb:9CYO|rcsb pdb:9CYP|rcsb pdb:9CYQ|rcsb pdb:9CYR|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-77387|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-9860927|panther:PTHR46047(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P35232	intact:EBI-10760263	intact:EBI-354213|uniprotkb:Q4VBQ0|ensembl:ENSP00000300408.3|ensembl:ENSP00000393320.3|ensembl:ENSP00000422182.3|ensembl:ENSP00000425035.2|ensembl:ENSP00000426433.3|ensembl:ENSP00000479488.1|ensembl:ENSP00000484113.1|uniprotkb:B4DY47	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:phb1_human(display_long)|uniprotkb:PHB1(gene name)|psi-mi:PHB1(display_short)|uniprotkb:PHB(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001268426.1|refseq:NP_002625.1|ensembl:ENSG00000167085.14(gene)|ensembl:ENST00000300408.8(transcript)|ensembl:ENST00000419140.7(transcript)|ensembl:ENST00000504124.6(transcript)|ensembl:ENST00000511832.6(transcript)|ensembl:ENST00000512041.7(transcript)|ensembl:ENST00000614445.5(transcript)|ensembl:ENST00000617874.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001850""(complement component C3a binding)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031871""(proteinase activated receptor binding)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0035632""(mitochondrial prohibitin complex)|go:""GO:0039529""(RIG-I signaling pathway)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0042113""(B cell activation)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044830""(modulation by host of viral RNA genome replication)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045917""(positive regulation of complement activation)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071897""(DNA biosynthetic process)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:2000323""(negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|panther:PTHR23222(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q99623	intact:EBI-10760263	intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875.1|uniprotkb:B4DP75	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001138303.1|refseq:NP_001254629.1|ensembl:ENSG00000215021.10(gene)|ensembl:ENST00000535923.6(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0009986""(cell surface)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030424""(axon)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0031536""(positive regulation of exit from mitosis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033147""(negative regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0033218""(amide binding)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0033600""(negative regulation of mammary gland epithelial cell proliferation)|go:""GO:0035632""(mitochondrial prohibitin complex)|go:""GO:0039529""(RIG-I signaling pathway)|go:""GO:0042113""(B cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046625""(sphingolipid binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050821""(protein stabilization)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060744""(mammary gland branching involved in thelarche)|go:""GO:0060749""(mammary gland alveolus development)|go:""GO:0060762""(regulation of branching involved in mammary gland duct morphogenesis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071944""(cell periphery)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1900208""(regulation of cardiolipin metabolic process)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902808""(positive regulation of cell cycle G1/S phase transition)|go:""GO:1904959""(regulation of cytochrome-c oxidase activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|rcsb pdb:8J4I|reactome:R-HSA-8949664|reactome:R-HSA-9840373|panther:PTHR23222(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:h4pib54mBeQgOKCe/hib58LM26w9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9NP58	intact:EBI-10760263	intact:EBI-2115230|uniprotkb:O75542|uniprotkb:Q49A66|uniprotkb:Q59GQ5|uniprotkb:Q6ZME6|uniprotkb:Q96ME8|uniprotkb:Q9HAQ6|uniprotkb:Q9HAQ7|ensembl:ENSP00000265316.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:abcb6_human(display_long)|uniprotkb:ABCB6(gene name)|psi-mi:ABCB6(display_short)|uniprotkb:MTABC3(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:UMAT(gene name synonym)|uniprotkb:Mitochondrial ABC transporter 3(gene name synonym)|uniprotkb:Ubiquitously-expressed mammalian ABC half transporter(gene name synonym)|uniprotkb:P-glycoprotein-related protein(gene name synonym)|uniprotkb:ABC-type heme transporter ABCB6(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24221(orthology-group)|ensembl:ENSG00000115657.14(gene)|ensembl:ENST00000265316.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005740""(mitochondrial envelope)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006778""(porphyrin-containing compound metabolic process)|go:""GO:0006779""(porphyrin-containing compound biosynthetic process)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007420""(brain development)|go:""GO:0015439""(ABC-type heme transporter activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:0015886""(heme transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0020037""(heme binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033013""(tetrapyrrole metabolic process)|go:""GO:0033162""(melanosome membrane)|go:""GO:0035351""(heme transmembrane transport)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0042168""(heme metabolic process)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|go:""GO:0043588""(skin development)|go:""GO:0046906""(tetrapyrrole binding)|go:""GO:0055085""(transmembrane transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098849""(cellular detoxification of cadmium ion)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:1903232""(melanosome assembly)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032410|interpro:IPR036640|interpro:IPR039421|mint:Q9NP58|rcsb pdb:3NH6|rcsb pdb:3NH9|rcsb pdb:3NHA|rcsb pdb:3NHB|rcsb pdb:7D7N|rcsb pdb:7D7R|rcsb pdb:7DNY|rcsb pdb:7DNZ|rcsb pdb:7EKL|rcsb pdb:7EKM|rcsb pdb:8FWK|rcsb pdb:8K7B|rcsb pdb:8K7C|rcsb pdb:8YR3|rcsb pdb:8YR4|reactome:R-HSA-1369007|reactome:R-HSA-5683371|refseq:NP_005680.1|efo:""Orphanet:241""|efo:""Orphanet:90044""|efo:""Orphanet:98938""|efo:""Orphanet:98942""|efo:""Orphanet:98943""|efo:""Orphanet:98944""|efo:""Orphanet:98945""|efo:""Orphanet:98946""|efo:""Orphanet:98947"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:3Zyw4d16oU1oT0eiAcOds3s1ZVQ9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q13423	intact:EBI-10760263	intact:EBI-1391318|uniprotkb:Q16796|uniprotkb:Q2TB60|uniprotkb:Q8N3V4|ensembl:ENSP00000264663.5|ensembl:ENSP00000343873.4|ensembl:ENSP00000499249.1|ensembl:ENSP00000499281.1|ensembl:ENSP00000499494.1|ensembl:ENSP00000499527.1|ensembl:ENSP00000499611.1|ensembl:ENSP00000499639.1|intact:EBI-21355735	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:nntm_human(display_long)|uniprotkb:NNT(gene name)|psi-mi:NNT(display_short)|uniprotkb:Nicotinamide nucleotide transhydrogenase(gene name synonym)|uniprotkb:Pyridine nucleotide transhydrogenase(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR10160(orthology-group)|efo:""Orphanet:361""|ensembl:ENSG00000112992.18(gene)|ensembl:ENST00000264663.9(transcript)|ensembl:ENST00000344920.9(transcript)|ensembl:ENST00000653251.1(transcript)|ensembl:ENST00000656666.1(transcript)|ensembl:ENST00000662525.1(transcript)|ensembl:ENST00000669601.1(transcript)|ensembl:ENST00000670904.1(transcript)|ensembl:ENST00000671668.1(transcript)|go:""GO:0003957""(""NAD(P)+ transhydrogenase (Si-specific) activity"")|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006740""(NADPH regeneration)|go:""GO:0008750""(""proton-translocating NAD(P)+ transhydrogenase activity"")|go:""GO:0010918""(positive regulation of mitochondrial membrane potential)|go:""GO:0016020""(membrane)|go:""GO:0032364""(intracellular oxygen homeostasis)|go:""GO:0033273""(response to vitamin)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0098803""(respiratory chain complex)|go:""GO:0098869""(cellular oxidant detoxification)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903285""(positive regulation of hydrogen peroxide catabolic process)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|interpro:IPR024605|interpro:IPR026255|interpro:IPR029035|interpro:IPR034300|interpro:IPR036291|mint:Q13423|rcsb pdb:1DJL|rcsb pdb:1PT9|rcsb pdb:1U31|reactome:R-HSA-71403|refseq:NP_036475.3|refseq:NP_892022.2|refseq:XP_005248331.1|refseq:XP_011512303.1|refseq:XP_016864782.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:iDKBuEy/JvV9q3s4/aHuu58+Gyk9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P31040	intact:EBI-10760263	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q8IW48|uniprotkb:Q59GW8|uniprotkb:A8K5J6|ensembl:ENSP00000264932.6	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)|uniprotkb:Malate dehydrogenase [quinone] flavoprotein subunit(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000073578.18(gene)|ensembl:ENST00000264932.11(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006105""(succinate metabolic process)|go:""GO:0006121""(mitochondrial electron transport, succinate to ubiquinone)|go:""GO:0007399""(nervous system development)|go:""GO:0008177""(""succinate dehydrogenase (quinone) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045273""(""respiratory chain complex II (succinate dehydrogenase)"")|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR030664|interpro:IPR036188|interpro:IPR037099|mint:P31040|rcsb pdb:6VAX|rcsb pdb:8DYD|rcsb pdb:8DYE|rcsb pdb:8GS8|reactome:R-HSA-611105|reactome:R-HSA-71403|reactome:R-HSA-9854311|refseq:NP_001281261.1|refseq:NP_004159.2|efo:""Orphanet:154""|efo:""Orphanet:29072""|efo:""Orphanet:3208""|efo:""Orphanet:44890""|dip:DIP-45851N|panther:PTHR11632(orthology-group)|ensembl:ENSP00000264932.6|ensembl:ENST00000510361.5|ensembl:ENSP00000427703.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P04083	intact:EBI-10760263	intact:EBI-354007|ensembl:ENSP00000257497.6|ensembl:ENSP00000366109.1|uniprotkb:B5BU38	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_000691.1|ensembl:ENSG00000135046.15(gene)|ensembl:ENST00000257497.11(transcript)|ensembl:ENST00000376911.2(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002685""(regulation of leukocyte migration)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007187""(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:""GO:0008289""(lipid binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014839""(myoblast migration involved in skeletal muscle regeneration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031514""(motile cilium)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032652""(regulation of interleukin-1 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0033031""(positive regulation of neutrophil apoptotic process)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045627""(positive regulation of T-helper 1 cell differentiation)|go:""GO:0045629""(negative regulation of T-helper 2 cell differentiation)|go:""GO:0045920""(negative regulation of exocytosis)|go:""GO:0046632""(alpha-beta T cell differentiation)|mint:P04083|go:""GO:0046883""(regulation of hormone secretion)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050482""(arachidonate secretion)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071621""(granulocyte chemotaxis)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|refseq:XP_011516911.1|dip:DIP-32875N|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O14818	intact:EBI-10760263	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|ensembl:ENSP00000359910.4|uniprotkb:Q5JXJ2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)|uniprotkb:Proteasome subunit alpha-4(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_002783.1|ensembl:ENSG00000101182.15(gene)|ensembl:ENST00000370873.9(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019773""(proteasome core complex, alpha-subunit complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR050115|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM3|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29363N|panther:PTHR11599(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9BVC6	intact:EBI-10760263	intact:EBI-1057733|ensembl:ENSP00000227525.3|ensembl:ENSP00000443990.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:tm109_human(display_long)|uniprotkb:TMEM109(gene name)|psi-mi:TMEM109(display_short)|uniprotkb:Mitsugumin-23(gene name synonym)|uniprotkb:Transmembrane protein 109(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_076997.1|ensembl:ENSG00000110108.11(gene)|ensembl:ENST00000227525.8(transcript)|ensembl:ENST00000536171.1(transcript)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0022843""(voltage-gated monoatomic cation channel activity)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0034702""(monoatomic ion channel complex)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071480""(cellular response to gamma radiation)|interpro:IPR039492|mint:Q9BVC6|panther:PTHR14550(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:KsibbFWmzuiZPpo4GqJikbMMaMQ9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P16070	intact:EBI-10760263	intact:EBI-490245|ensembl:ENSP00000398632.2|uniprotkb:P22511|uniprotkb:Q04858|uniprotkb:Q13419|uniprotkb:Q13957|uniprotkb:Q13958|uniprotkb:Q13959|uniprotkb:Q13960|uniprotkb:Q13961|uniprotkb:Q13967|uniprotkb:Q13968|uniprotkb:Q13980|uniprotkb:Q15861|uniprotkb:Q16064|uniprotkb:Q16065|uniprotkb:Q16066|uniprotkb:Q16208|uniprotkb:Q16522|uniprotkb:Q86T72|uniprotkb:Q86Z27|uniprotkb:Q8N694|uniprotkb:Q92493|uniprotkb:Q96J24|uniprotkb:Q9UJ36|uniprotkb:Q9H5A5|uniprotkb:A5YRN9|uniprotkb:Q9UC28|uniprotkb:Q9UC29|uniprotkb:Q9UC30|uniprotkb:Q9UCB0|uniprotkb:D3DR12|uniprotkb:D3DR13|uniprotkb:B6EAT9|uniprotkb:O95370	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:cd44_human(display_long)|uniprotkb:Epican(gene name synonym)|uniprotkb:CDw44(gene name synonym)|uniprotkb:Phagocytic glycoprotein I(gene name synonym)|uniprotkb:Extracellular matrix receptor III(gene name synonym)|uniprotkb:HUTCH-I(gene name synonym)|uniprotkb:Phagocytic glycoprotein 1(gene name synonym)|uniprotkb:GP90 lymphocyte homing/adhesion receptor(gene name synonym)|uniprotkb:Hermes antigen(gene name synonym)|uniprotkb:Hyaluronate receptor(gene name synonym)|uniprotkb:Heparan sulfate proteoglycan(gene name synonym)|uniprotkb:CD44(gene name)|psi-mi:CD44(display_short)|uniprotkb:LHR(gene name synonym)|uniprotkb:MDU2(gene name synonym)|uniprotkb:MDU3(gene name synonym)|uniprotkb:MIC4(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0009986""(cell surface)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|ensembl:ENSG00000026508.21(gene)|ensembl:ENST00000428726.8(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005540""(hyaluronic acid binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005925""(focal adhesion)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0016477""(cell migration)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042995""(cell projection)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0051216""(cartilage development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070487""(monocyte aggregation)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:1900625""(positive regulation of monocyte aggregation)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000392""(regulation of lamellipodium morphogenesis)|interpro:IPR000538(Link)|interpro:IPR001231(CD44 antigen)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR043210|mint:P16070|rcsb pdb:1POZ|rcsb pdb:1UUH|rcsb pdb:2I83|rcsb pdb:4PZ3|rcsb pdb:4PZ4|rcsb pdb:6TXS|reactome:R-HSA-1474228|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2160916|reactome:R-HSA-6798695|reactome:R-HSA-877300|refseq:NP_000601.3|refseq:NP_001001389.1|refseq:NP_001001390.1|refseq:NP_001001391.1|refseq:NP_001001392.1|refseq:NP_001189484.1|refseq:NP_001189485.1|refseq:NP_001189486.1|refseq:XP_011518790.1|dip:DIP-1121N|panther:PTHR10225(orthology-group)|ensembl:ENST00000263398.11|ensembl:ENSP00000263398.6|ensembl:ENST00000278386.10|ensembl:ENSP00000278386.6|ensembl:ENST00000352818.8|ensembl:ENSP00000309732.6|ensembl:ENST00000415148.6|ensembl:ENSP00000389830.2|ensembl:ENSP00000398632.2|ensembl:ENST00000433892.6|ensembl:ENSP00000392331.2|ensembl:ENST00000434472.6|ensembl:ENSP00000404447.2"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:QOb28rF7/ryqfz/ylJFTyL3aoAc9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q01650	intact:EBI-10760263	intact:EBI-6138761|uniprotkb:Q8IV97|uniprotkb:Q9UBN8|uniprotkb:Q9UP15|uniprotkb:Q9UQC0|ensembl:ENSP00000261622.4	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:lat1_human(display_long)|uniprotkb:SLC7A5(gene name)|psi-mi:SLC7A5(display_short)|uniprotkb:CD98LC(gene name synonym)|uniprotkb:LAT1(gene name synonym)|uniprotkb:MPE16(gene name synonym)|uniprotkb:4F2 light chain(gene name synonym)|uniprotkb:CD98 light chain(gene name synonym)|uniprotkb:Integral membrane protein E16(gene name synonym)|uniprotkb:L-type amino acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 7 member 5(gene name synonym)|uniprotkb:y+ system cationic amino acid transporter(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_003477.4|ensembl:ENSG00000103257.10(gene)|ensembl:ENST00000261622.5(transcript)|go:""GO:0002720""(positive regulation of cytokine production involved in immune response)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015196""(L-tryptophan transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015349""(thyroid hormone transmembrane transporter activity)|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032328""(alanine transport)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042908""(xenobiotic transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0089718""(amino acid import across plasma membrane)|go:""GO:0097421""(liver regeneration)|go:""GO:0098591""(external side of apical plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903577""(cellular response to L-arginine)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904556""(L-tryptophan transmembrane transport)|go:""GO:1905460""(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:""GO:1905534""(positive regulation of L-leucine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004760(L-type amino acid transporter)|interpro:IPR050598|mint:Q01650|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|rcsb pdb:8XPU|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-71240|panther:PTHR11785(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:GrXTCUhrHMNCnvscgx1ink2opoU9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P07099	intact:EBI-10760263	intact:EBI-6138796|uniprotkb:B2R8N0|uniprotkb:Q5VTJ6|uniprotkb:Q9NP75|uniprotkb:Q9NPE7|uniprotkb:Q9NQU6|uniprotkb:Q9NQU7|uniprotkb:Q9NQU8|uniprotkb:Q9NQU9|uniprotkb:Q9NQV0|uniprotkb:Q9NQV1|uniprotkb:Q9NQV2|ensembl:ENSP00000272167.5|ensembl:ENSP00000355802.4|ensembl:ENSP00000480004.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:hyep_human(display_long)|uniprotkb:EPHX1(gene name)|psi-mi:EPHX1(display_short)|uniprotkb:EPHX(gene name synonym)|uniprotkb:EPOX(gene name synonym)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000143819.13(gene)|ensembl:ENST00000272167.10(transcript)|ensembl:ENST00000366837.5(transcript)|ensembl:ENST00000614058.4(transcript)|go:""GO:0004301""(epoxide hydrolase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0009636""(response to toxic substance)|go:""GO:0019369""(arachidonate metabolic process)|go:""GO:0033961""(cis-stilbene-oxide hydrolase activity)|go:""GO:0097176""(epoxide metabolic process)|go:""GO:0120253""(hydrocarbon catabolic process)|go:""GO:1903165""(response to polycyclic arene)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|mint:P07099|reactome:R-HSA-211945|refseq:NP_000111.1|refseq:NP_001129490.1|refseq:NP_001278092.1|efo:""Orphanet:238475""|panther:PTHR21661(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:VtIgDuQpQQbLSdFLOBBx9yHHiBE9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9Y4W6	intact:EBI-10760263	intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym)|uniprotkb:AFG3-like protein 2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000141385.12(gene)|ensembl:ENST00000269143.8(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005745""(m-AAA complex)|go:""GO:0006508""(proteolysis)|go:""GO:0007409""(axonogenesis)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0008053""(mitochondrial fusion)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016485""(protein processing)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0021675""(nerve development)|go:""GO:0030163""(protein catabolic process)|go:""GO:0033619""(membrane protein proteolysis)|go:""GO:0034982""(mitochondrial protein processing)|go:""GO:0036444""(calcium import into the mitochondrion)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042407""(cristae formation)|go:""GO:0042552""(myelination)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:0051604""(protein maturation)|go:""GO:0055001""(muscle cell development)|go:""GO:0060013""(righting reflex)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0072753""(cellular response to glutathione)|go:""GO:0110097""(regulation of calcium import into the mitochondrion)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:0141164""(mitochondrial protein quality control)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|interpro:IPR050928|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664|reactome:R-HSA-9837999|refseq:NP_006787.2|efo:""Orphanet:101109""|efo:""Orphanet:313772""|panther:PTHR43655(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P11279	intact:EBI-10760263	intact:EBI-2805407|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40|ensembl:ENSP00000333298.4|uniprotkb:B4DWL3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_005552.3|ensembl:ENSG00000185896.11(gene)|ensembl:ENST00000332556.5(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0001618""(virus receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0044754""(autolysosome)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0061474""(phagolysosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072594""(establishment of protein localization to organelle)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0140507""(granzyme-mediated programmed cell death signaling pathway)|go:""GO:1902513""(regulation of organelle transport along microtubule)|interpro:IPR002000(""Lysosome-associated membrane glycoprotein (Lamp)/CD68"")|interpro:IPR018134|interpro:IPR048524|interpro:IPR048528|mint:P11279|rcsb pdb:8ATH|rcsb pdb:8FY5|rcsb pdb:8FYF|reactome:R-HSA-6798695|dip:DIP-44670N|panther:PTHR11506(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P06576	intact:EBI-10760263	intact:EBI-356231|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803|ensembl:ENSP00000262030.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001677.2|interpro:IPR036121|ensembl:ENSG00000110955.9(gene)|ensembl:ENST00000262030.8(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005886""(plasma membrane)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0006933""(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:""GO:0009986""(cell surface)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0043532""(angiostatin binding)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0045267""(obsolete proton-transporting ATP synthase, catalytic core)|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0051453""(regulation of intracellular pH)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR050053|interpro:IPR055190|mint:P06576|rcsb pdb:8H9E|rcsb pdb:8H9I|rcsb pdb:8H9L|rcsb pdb:8H9P|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KI3|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|reactome:R-HSA-9837999|panther:PTHR15184(orthology-group)|ensembl:ENSP00000262030.3"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q8TCT9	intact:EBI-10760263	intact:EBI-347472|uniprotkb:Q540H8|uniprotkb:Q5JWP2|uniprotkb:Q5JWP3|uniprotkb:Q5JWP4|uniprotkb:Q5JWP5|uniprotkb:Q7Z4F2|uniprotkb:Q86Y35|uniprotkb:Q95H87|uniprotkb:Q9H110|uniprotkb:Q9H111|uniprotkb:Q15K36|uniprotkb:B2RAY5|uniprotkb:E1P5L3|ensembl:ENSP00000343032.5	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:hm13_human(display_long)|uniprotkb:HM13(gene name)|psi-mi:HM13(display_short)|uniprotkb:H13(gene name synonym)|uniprotkb:PSL3(gene name synonym)|uniprotkb:SPP(gene name synonym)|uniprotkb:Signal peptide peptidase(gene name synonym)|uniprotkb:Presenilin-like protein 3(gene name synonym)|uniprotkb:Intramembrane protease 1(gene name synonym)|uniprotkb:IMP1(gene name synonym)|uniprotkb:MSTP086(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_110416.1|refseq:NP_848695.1|refseq:NP_848696.1|refseq:NP_848697.1|panther:PTHR12174(orthology-group)|ensembl:ENSG00000101294.20(gene)|ensembl:ENST00000340852.9(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006465""(signal peptide processing)|go:""GO:0008233""(peptidase activity)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0033619""(membrane protein proteolysis)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0036513""(Derlin-1 retrotranslocation complex)|go:""GO:0042500""(aspartic endopeptidase activity, intramembrane cleaving)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:1904211""(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR007369(Peptidase A22B, signal peptide peptidase)|mint:Q8TCT9|reactome:R-HSA-9707587"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:DxNjJDcc+zomfXAj0TEaByKeNqc9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P02786	intact:EBI-10760263	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224.4|ensembl:ENSP00000376197.3|ensembl:ENSP00000513646.1|ensembl:ENSP00000513654.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:476113""|ensembl:ENSG00000072274.14(gene)|ensembl:ENST00000360110.9(transcript)|ensembl:ENST00000392396.7(transcript)|ensembl:ENST00000698280.1(transcript)|ensembl:ENST00000698291.1(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004998""(transferrin receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010039""(response to iron ion)|go:""GO:0010042""(response to manganese ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010637""(negative regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033572""(transferrin transport)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0046688""(response to copper ion)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0072562""(blood microparticle)|go:""GO:0098944""(postsynaptic recycling endosome membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|interpro:IPR046450|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|rcsb pdb:7ZQS|rcsb pdb:8P0Z|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9725554|refseq:NP_001121620.1|refseq:NP_001300894.1|refseq:NP_001300895.1|refseq:NP_003225.2|dip:DIP-2736N|panther:PTHR10404(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P25705	intact:EBI-10760263	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|ensembl:ENSP00000282050.2|ensembl:ENSP00000381736.5|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|intact:EBI-11032691	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:254913""|ensembl:ENSG00000152234.16(gene)|ensembl:ENST00000282050.6(transcript)|ensembl:ENST00000398752.11(transcript)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0002020""(protease binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0009986""(cell surface)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0043531""(ADP binding)|go:""GO:0043532""(angiostatin binding)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0045121""(membrane raft)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0045471""(response to ethanol)|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0071732""(cellular response to nitric oxide)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|rcsb pdb:8H9E|rcsb pdb:8H9I|rcsb pdb:8H9L|rcsb pdb:8H9P|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KI3|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613|reactome:R-HSA-9837999|refseq:NP_001001935.1|refseq:NP_001001937.1|refseq:NP_001244263.1|refseq:NP_001244264.1|refseq:NP_004037.1|dip:DIP-32871N|panther:PTHR48082(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61026	intact:EBI-10760263	intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710.4	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_057215.3|ensembl:ENSG00000084733.11(gene)|ensembl:ENST00000264710.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0007409""(axonogenesis)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0019003""(GDP binding)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0031489""(myosin V binding)|go:""GO:0032593""(insulin-responsive compartment)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045200""(establishment of neuroblast polarity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070382""(exocytic vesicle)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0097051""(establishment of protein localization to endoplasmic reticulum membrane)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0099503""(secretory vesicle)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:P61026|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9UHG3	intact:EBI-10760263	intact:EBI-2908417|uniprotkb:B2RB14|uniprotkb:O94982|uniprotkb:Q8N4N5|uniprotkb:Q96QM8|uniprotkb:B7Z9P8|ensembl:ENSP00000387654.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:pcyox_human(display_long)|uniprotkb:PCYOX1(gene name)|psi-mi:PCYOX1(display_short)|uniprotkb:KIAA0908(gene name synonym)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Prenylcysteine lyase(gene name synonym)|uniprotkb:UNQ597/PRO1183(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_057381.3|ensembl:ENSG00000116005.12(gene)|ensembl:ENST00000433351.7(transcript)|go:""GO:0001735""(prenylcysteine oxidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0030327""(prenylated protein catabolic process)|go:""GO:0030328""(prenylcysteine catabolic process)|go:""GO:0034361""(very-low-density lipoprotein particle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071949""(FAD binding)|go:""GO:0102149""(farnesylcysteine lyase activity)|interpro:IPR010795(Prenylcysteine lyase)|interpro:IPR017046(Prenylcysteine oxidase)|interpro:IPR036188|mint:Q9UHG3|panther:PTHR15944(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:E7WR6qZZuoGqmWQ+CX6PeZX/yEw9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P51149	intact:EBI-10760263	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062.3|ensembl:ENSP00000501618.1|ensembl:ENSP00000502000.1|ensembl:ENSP00000502088.1|ensembl:ENSP00000502486.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000075785.14(gene)|ensembl:ENST00000265062.8(transcript)|ensembl:ENST00000674589.1(transcript)|ensembl:ENST00000675342.1(transcript)|ensembl:ENST00000675497.1(transcript)|ensembl:ENST00000676214.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0019003""(GDP binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0036466""(synaptic vesicle recycling via endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045453""(bone resorption)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048524""(positive regulation of viral process)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090383""(phagosome acidification)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0097208""(alveolar lamellar body)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:1903542""(negative regulation of exosomal secretion)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1905366""(negative regulation of intralumenal vesicle formation)|go:""GO:1905394""(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:3LAW|rcsb pdb:6IYB|rcsb pdb:6WCW|rcsb pdb:7F6J|rcsb pdb:8KB8|rcsb pdb:8ZQ3|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|refseq:NP_004628.4|efo:""Orphanet:99936""|dip:DIP-39879N|panther:PTHR47981(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9H845	intact:EBI-10760263	intact:EBI-2510719|uniprotkb:Q8WXX3|uniprotkb:D3DNB8|ensembl:ENSP00000312618.7|ensembl:ENSP00000506340.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"dip:DIP-53699N|efo:""Orphanet:99901""|ensembl:ENSG00000177646.20(gene)|ensembl:ENST00000308982.12(transcript)|ensembl:ENST00000681583.1(transcript)|go:""GO:0001676""(long-chain fatty acid metabolic process)|go:""GO:0003995""(acyl-CoA dehydrogenase activity)|go:""GO:0004466""(long-chain fatty acyl-CoA dehydrogenase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0030425""(dendrite)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032981""(mitochondrial respiratory chain complex I assembly)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0051791""(medium-chain fatty acid metabolic process)|go:""GO:0070991""(medium-chain fatty acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|interpro:IPR046373|interpro:IPR049448|mint:Q9H845|rcsb pdb:8PHE|rcsb pdb:8PHF|reactome:R-HSA-6799198|refseq:NP_054768.2|panther:PTHR43884(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q03519	intact:EBI-10760263	intact:EBI-780781|uniprotkb:Q9UQ83|uniprotkb:O95410|uniprotkb:B0V2J8|uniprotkb:Q53FI6|uniprotkb:Q5HY71|uniprotkb:Q96PT8|ensembl:ENSP00000364032.3|ensembl:ENSP00000372599.4|ensembl:ENSP00000372726.4|ensembl:ENSP00000390013.2|ensembl:ENSP00000394101.2|ensembl:ENSP00000513722.1|ensembl:ENSP00000513733.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:tap2_human(display_long)|uniprotkb:ATP-binding cassette sub-family B member 3(gene name synonym)|uniprotkb:Peptide transporter TAP2(gene name synonym)|uniprotkb:Peptide supply factor 2(gene name synonym)|uniprotkb:Peptide transporter PSF2(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 2(gene name synonym)|uniprotkb:TAP2(gene name)|psi-mi:TAP2(display_short)|uniprotkb:ABCB3(gene name synonym)|uniprotkb:PSF2(gene name synonym)|uniprotkb:RING11(gene name synonym)|uniprotkb:Y1(gene name synonym)|uniprotkb:Really interesting new gene 11 protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"dip:DIP-322N|ensembl:ENSG00000204267.19(gene)|ensembl:ENSG00000206235.8(gene)|ensembl:ENSG00000206299.8(gene)|ensembl:ENSG00000228582.9(gene)|ensembl:ENSG00000237599.9(gene)|ensembl:ENST00000374897.4(transcript)|ensembl:ENST00000383118.8(transcript)|ensembl:ENST00000383239.8(transcript)|ensembl:ENST00000419142.6(transcript)|ensembl:ENST00000443713.6(transcript)|ensembl:ENST00000698440.1(transcript)|ensembl:ENST00000698448.1(transcript)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002485""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:""GO:0002489""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent)|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0015031""(protein transport)|go:""GO:0015433""(ABC-type peptide antigen transporter activity)|go:""GO:0015440""(ABC-type peptide transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0023029""(MHC class Ib protein binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0042825""(TAP complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0046967""(cytosol to endoplasmic reticulum transport)|go:""GO:0046968""(peptide antigen transport)|go:""GO:0046978""(TAP1 binding)|go:""GO:0046980""(tapasin binding)|go:""GO:0055085""(transmembrane transport)|go:""GO:1904680""(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03519|rcsb pdb:5U1D|rcsb pdb:8T46|rcsb pdb:8T4E|rcsb pdb:8T4F|rcsb pdb:8T4G|rcsb pdb:8T4H|rcsb pdb:8T4I|rcsb pdb:8T4J|reactome:R-HSA-1236974|reactome:R-HSA-983170|refseq:NP_000535.3|refseq:NP_001276972.1|refseq:NP_061313.2|efo:""Orphanet:34592""|panther:PTHR24221(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:w7pDqjoSODoB8qMag1ycxcapvQ09606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q96KA5	intact:EBI-10760263	intact:EBI-3216282|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1|ensembl:ENSP00000313854.5|ensembl:ENSP00000480372.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:clp1l_human(display_long)|uniprotkb:Cleft lip and palate transmembrane protein 1-like protein(gene name synonym)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_110409.2|ensembl:ENSG00000049656.14(gene)|ensembl:ENSG00000274811.3(gene)|ensembl:ENST00000320895.10(transcript)|ensembl:ENST00000620010.3(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0017128""(phospholipid scramblase activity)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|mint:Q96KA5|panther:PTHR21347(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9HDC9	intact:EBI-10760263	intact:EBI-723950|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1|ensembl:ENSP00000217456.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_065392.1|refseq:XP_005260820.1|ensembl:ENSG00000101474.12(gene)|ensembl:ENST00000217456.3(transcript)|go:""GO:0004064""(arylesterase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016844""(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|panther:PTHR10426(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P05023	intact:EBI-10760263	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|ensembl:ENSP00000295598.5|intact:EBI-10963133	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR43294(orthology-group)|ensembl:ENSG00000163399.16(gene)|ensembl:ENST00000295598.10(transcript)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0005391""(""P-type sodium:potassium-exchanging transporter activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0007231""(osmosensory signaling pathway)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016791""(phosphatase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030315""(T-tubule)|go:""GO:0030424""(axon)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031090""(organelle membrane)|go:""GO:0031402""(sodium ion binding)|go:""GO:0031947""(negative regulation of glucocorticoid biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0045823""(positive regulation of heart contraction)|go:""GO:0045989""(positive regulation of striated muscle contraction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060342""(photoreceptor inner segment membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086009""(membrane repolarization)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903416""(response to glycoside)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990239""(steroid hormone binding)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|interpro:IPR050510|mint:P05023|rcsb pdb:7E1Z|rcsb pdb:7E20|rcsb pdb:7E21|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|efo:""Orphanet:521414""|efo:""Orphanet:564178"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P36542	intact:EBI-10760263	intact:EBI-711768|ensembl:ENSP00000349142.7|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000165629.20(gene)|ensembl:ENST00000356708.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016020""(membrane)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|rcsb pdb:8H9E|rcsb pdb:8H9F|rcsb pdb:8H9I|rcsb pdb:8H9J|rcsb pdb:8H9L|rcsb pdb:8H9M|rcsb pdb:8H9P|rcsb pdb:8H9Q|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|reactome:R-HSA-9837999|refseq:NP_001001973.1|refseq:NP_005165.1|panther:PTHR11693(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q99805	intact:EBI-10760263	intact:EBI-2852254|uniprotkb:Q2TAY5|uniprotkb:A8K399|ensembl:ENSP00000365567.3|ensembl:ENSP00000493515.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:tm9s2_human(display_long)|uniprotkb:TM9SF2(gene name)|psi-mi:TM9SF2(display_short)|uniprotkb:p76(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_004791.1|ensembl:ENSG00000125304.10(gene)|ensembl:ENST00000376387.5(transcript)|ensembl:ENST00000642475.1(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005886""(plasma membrane)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0006688""(glycosphingolipid biosynthetic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0010908""(regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|interpro:IPR004240(""Nonaspanin (TM9SF)"")|mint:Q99805|panther:PTHR10766(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:qg5QSnzX8+4H0Nfab7Ci9n9igc09606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P46977	intact:EBI-10760263	intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472.3|ensembl:ENSP00000436962.1|ensembl:ENSP00000497336.1|uniprotkb:B4DJ24|uniprotkb:E9PNQ1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:370921""|ensembl:ENSG00000134910.14(gene)|ensembl:ENST00000392708.9(transcript)|ensembl:ENST00000529196.5(transcript)|ensembl:ENST00000649491.1(transcript)|go:""GO:0004579""(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0043686""(co-translational protein modification)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0046872""(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|interpro:IPR048307|interpro:IPR054479|mint:P46977|rcsb pdb:6S7O|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_001265432.1|refseq:NP_001265433.1|refseq:NP_689926.1|refseq:XP_011541109.1|panther:PTHR13872(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O60313	intact:EBI-10760263	intact:EBI-1054131|uniprotkb:D3DNW4|uniprotkb:E5KLJ5|uniprotkb:E5KLJ6|uniprotkb:E5KLJ7|uniprotkb:E5KLK1|uniprotkb:E5KLK2|ensembl:ENSP00000354429.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:opa1_human(display_long)|uniprotkb:Optic atrophy protein 1(gene name synonym)|uniprotkb:OPA1(gene name)|psi-mi:OPA1(display_short)|uniprotkb:KIAA0567(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"efo:""Orphanet:1215""|efo:""Orphanet:98673""|efo:""Orphanet:1239""|ensembl:ENSG00000198836.11(gene)|ensembl:ENST00000361828.7(transcript)|go:""GO:0000002""(mitochondrial genome maintenance)|go:""GO:0000266""(mitochondrial fission)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006915""(apoptotic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007007""(inner mitochondrial membrane organization)|go:""GO:0007601""(visual perception)|go:""GO:0008017""(microtubule binding)|go:""GO:0008053""(mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0019896""(axonal transport of mitochondrion)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030425""(dendrite)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0042407""(cristae formation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046039""(GTP metabolic process)|go:""GO:0051259""(protein complex oligomerization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0097749""(membrane tubulation)|go:""GO:0140523""(GTPase-dependent fusogenic activity)|go:""GO:0180020""(membrane bending activity)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990627""(mitochondrial inner membrane fusion)|go:""GO:2000330""(positive regulation of T-helper 17 cell lineage commitment)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR045063|interpro:IPR045817|mint:O60313|rcsb pdb:6JTG|rcsb pdb:8CT1|rcsb pdb:8CT9|rcsb pdb:8EEW|rcsb pdb:8EF7|rcsb pdb:8EFF|rcsb pdb:8EFR|rcsb pdb:8EFS|rcsb pdb:8EFT|reactome:R-HSA-169911|reactome:R-HSA-9837999|refseq:NP_056375.2|refseq:NP_570844.1|refseq:NP_570846.1|refseq:NP_570847.2|refseq:NP_570849.2|refseq:NP_570850.2|panther:PTHR11566(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:1VmujqR2PEGFIgK9mV+8g57wVb89606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61106	intact:EBI-10760263	intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946.4|ensembl:ENSP00000515613.1|ensembl:ENSP00000515614.1|intact:EBI-21352994	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_057406.2|ensembl:ENSG00000119396.12(gene)|ensembl:ENST00000373840.9(transcript)|ensembl:ENST00000703999.1(transcript)|ensembl:ENST00000704000.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001845""(phagolysosome assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005795""(Golgi stack)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019003""(GDP binding)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0031489""(myosin V binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0042175""(nuclear outer membrane-endoplasmic reticulum membrane network)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090382""(phagosome maturation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|interpro:IPR050209|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9UIQ6	intact:EBI-10760263	intact:EBI-2805360|uniprotkb:O00769|uniprotkb:Q9TNQ2|uniprotkb:Q9TNQ3|uniprotkb:Q9UIQ7|uniprotkb:Q59H76|uniprotkb:Q15145|ensembl:ENSP00000231368.5	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:lcap_human(display_long)|uniprotkb:OTASE(gene name synonym)|uniprotkb:Oxytocinase(gene name synonym)|uniprotkb:Insulin-regulated membrane aminopeptidase(gene name synonym)|uniprotkb:Insulin-responsive aminopeptidase(gene name synonym)|uniprotkb:Placental leucine aminopeptidase(gene name synonym)|uniprotkb:LNPEP(gene name)|psi-mi:LNPEP(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_005566.2|refseq:NP_787116.2|ensembl:ENSG00000113441.16(gene)|ensembl:ENST00000231368.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0002480""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007565""(female pregnancy)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0042277""(peptide binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|interpro:IPR045357|interpro:IPR050344|mint:Q9UIQ6|rcsb pdb:4P8Q|rcsb pdb:4PJ6|rcsb pdb:4Z7I|rcsb pdb:5C97|rcsb pdb:5JHQ|rcsb pdb:5MJ6|rcsb pdb:7ZYF|rcsb pdb:8CGP|rcsb pdb:8CGW|rcsb pdb:8P0I|reactome:R-HSA-1236977|reactome:R-HSA-1445148|reactome:R-HSA-983168|panther:PTHR11533(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:IOU7GW8f6aBYAjIUQXFKbU5Hqkw9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9H3N1	intact:EBI-10760263	intact:EBI-1051115|uniprotkb:Q8N487|uniprotkb:Q8NBN5|uniprotkb:Q9Y4T6|uniprotkb:B2R7A4|ensembl:ENSP00000393316.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:tmx1_human(display_long)|uniprotkb:Transmembrane Trx-related protein(gene name synonym)|uniprotkb:TMX1(gene name)|psi-mi:TMX1(display_short)|uniprotkb:TXNDC1(gene name synonym)|uniprotkb:TMX(gene name synonym)|uniprotkb:TXNDC(gene name synonym)|uniprotkb:PSEC0085(orf name)|uniprotkb:UNQ235/PRO268(orf name)|uniprotkb:Thioredoxin domain-containing protein 1(gene name synonym)|uniprotkb:Protein disulfide-isomerase TMX1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_110382.3|ensembl:ENSG00000139921.13(gene)|ensembl:ENST00000457354.7(transcript)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0010868""(negative regulation of triglyceride biosynthetic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:1904294""(positive regulation of ERAD pathway)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR052454|mint:Q9H3N1|rcsb pdb:1X5E|panther:PTHR46107(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:ZJH5N22Dnrk+SXa3Ysqqfu1md/I9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P39656	intact:EBI-10760263	intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457.3|uniprotkb:B4DJE3|uniprotkb:B4DLI2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000244038.11(gene)|ensembl:ENST00000415136.6(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0034097""(response to cytokine)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042110""(T cell activation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548|refseq:NP_005207.2|efo:""Orphanet:300536""|panther:PTHR10830(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O00116	intact:EBI-10760263	intact:EBI-2838732|uniprotkb:A5D8U9|uniprotkb:Q2TU35|ensembl:ENSP00000264167.4	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:adas_human(display_long)|uniprotkb:AGPS(gene name)|psi-mi:AGPS(display_short)|uniprotkb:Aging-associated gene 5 protein(gene name synonym)|uniprotkb:Alkylglycerone-phosphate synthase(gene name synonym)|uniprotkb:AAG5(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000018510.18(gene)|ensembl:ENST00000264167.11(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0008609""(alkylglycerone-phosphate synthase activity)|go:""GO:0008610""(lipid biosynthetic process)|go:""GO:0008611""(ether lipid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0071949""(FAD binding)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR025650|interpro:IPR036318|mint:O00116|reactome:R-HSA-75896|reactome:R-HSA-9033241|reactome:R-HSA-9033500|refseq:NP_003650.1|efo:""Orphanet:309803""|panther:PTHR46568(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:P8f6+j/f+WID0lFZnLIvVN5OSzM9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P27824	intact:EBI-10760263	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000247461.4|ensembl:ENSP00000391646.2|ensembl:ENSP00000421434.2|ensembl:ENSP00000421813.2|ensembl:ENSP00000424063.1|ensembl:ENSP00000424745.2|ensembl:ENSP00000491760.1|ensembl:ENSP00000492372.1|ensembl:ENSP00000492868.1|ensembl:ENSP00000505013.1|ensembl:ENSP00000505202.1|ensembl:ENSP00000505526.1|ensembl:ENSP00000505960.1|ensembl:ENSP00000506003.1|ensembl:ENSP00000506021.1|ensembl:ENSP00000506061.1|ensembl:ENSP00000506078.1|ensembl:ENSP00000506509.1|ensembl:ENSP00000506568.1|ensembl:ENSP00000506583.1|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|ensembl:ENSG00000127022.16(gene)|ensembl:ENSG00000283777.2(gene)|ensembl:ENST00000247461.9(transcript)|ensembl:ENST00000452673.6(transcript)|ensembl:ENST00000502296.6(transcript)|ensembl:ENST00000504734.5(transcript)|ensembl:ENST00000509563.2(transcript)|ensembl:ENST00000513246.6(transcript)|ensembl:ENST00000638425.1(transcript)|ensembl:ENST00000638706.2(transcript)|ensembl:ENST00000639938.1(transcript)|ensembl:ENST00000680013.1(transcript)|ensembl:ENST00000680042.1(transcript)|ensembl:ENST00000680092.1(transcript)|ensembl:ENST00000680618.1(transcript)|ensembl:ENST00000681072.1(transcript)|ensembl:ENST00000681168.1(transcript)|ensembl:ENST00000681476.1(transcript)|ensembl:ENST00000681674.1(transcript)|ensembl:ENST00000681712.1(transcript)|ensembl:ENST00000681733.1(transcript)|ensembl:ENST00000681903.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006457""(protein folding)|go:""GO:0009306""(protein secretion)|go:""GO:0016020""(membrane)|go:""GO:0019082""(viral protein processing)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0036503""(ERAD pathway)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0044322""(endoplasmic reticulum quality control compartment)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098793""(presynapse)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|dip:DIP-457N|panther:PTHR11073(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P16615	intact:EBI-10760263	intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045.2	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	"psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:""Endoplasmic reticulum class 1/2 Ca(2+) ATPase""(gene name synonym)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034088|imex:IM-29092-85	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR42861(orthology-group)|efo:""Orphanet:218""|efo:""Orphanet:79151""|ensembl:ENSG00000174437.18(gene)|ensembl:ENST00000539276.7(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0005388""(P-type calcium transporter activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006984""(ER-nucleus signaling pathway)|go:""GO:0007155""(cell adhesion)|go:""GO:0008544""(epidermis development)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0010882""(regulation of cardiac muscle contraction by calcium ion signaling)|go:""GO:0014801""(longitudinal sarcoplasmic reticulum)|go:""GO:0014883""(transition between fast and slow fiber)|go:""GO:0014898""(cardiac muscle hypertrophy in response to stress)|go:""GO:0016020""(membrane)|go:""GO:0016240""(autophagosome membrane docking)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0032470""(positive regulation of endoplasmic reticulum calcium ion concentration)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0033292""(T-tubule organization)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0070296""(sarcoplasmic reticulum calcium ion transport)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0086036""(regulation of cardiac muscle cell membrane potential)|go:""GO:0086039""(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:""GO:0090534""(calcium ion-transporting ATPase complex)|go:""GO:0097470""(ribbon synapse)|go:""GO:0098909""(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:""GO:0106222""(lncRNA binding)|go:""GO:0140056""(organelle localization by membrane tethering)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1903233""(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:""GO:1903515""(calcium ion transport from cytosol to endoplasmic reticulum)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1990036""(calcium ion import into sarcoplasmic reticulum)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|rcsb pdb:7E7S|rcsb pdb:7W7T|rcsb pdb:7W7U|rcsb pdb:7W7V|rcsb pdb:7W7W|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_005253945.1|refseq:XP_011536704.1|dip:DIP-33868N"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606	intact-crc:1B48D4389B4CBA3A|rigid:2QJuQMbKjXxAdL/eLpj49LT4guE	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B2Z0	uniprotkb:P63244	intact:EBI-27034157	intact:EBI-296739|uniprotkb:P25388|ensembl:ENSP00000426909.1|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	psi-mi:a0a0f6b2z0_salt1(display_long)|uniprotkb:STM14_2428(locus name)	psi-mi:rack1_human(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Receptor of activated protein C kinase 1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034162|imex:IM-29092-105	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:A0A0F6B2Z0|refseq:WP_000492926.1	"ensembl:ENSG00000204628.12(gene)|ensembl:ENST00000512805.6(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007369""(gastrulation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015935""(small ribosomal subunit)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030332""(cyclin binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042998""(positive regulation of Golgi to plasma membrane protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043204""(perikaryon)|go:""GO:0043473""(pigmentation)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045296""(cadherin binding)|refseq:NP_006089.1|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048511""(rhythmic process)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051901""(positive regulation of mitochondrial depolarization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0106070""(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:1900102""(negative regulation of endoplasmic reticulum unfolded protein response)|go:""GO:1903751""(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:1990630""(IRE1-RACK1-PP2A complex)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000543""(positive regulation of gastrulation)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001125""(negative regulation of translational frameshifting)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR045223|mint:P63244|rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|dip:DIP-46736N|panther:PTHR19868(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/24	rogid:h37KSGoIrBoGPZmHVr5lbkxjGXE588858	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	intact-crc:999261E0F9A2AF07|rigid:Tdra6f7Mj+XuovPhZPfkQrFtUvI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:Q9NTJ5	intact:EBI-13953897	intact:EBI-3917235|uniprotkb:Q7LA14|uniprotkb:A8K527|uniprotkb:Q96AX7|uniprotkb:Q9NQ46|uniprotkb:Q9NQ57|uniprotkb:O94935|uniprotkb:Q7LA22|ensembl:ENSP00000373713.4|uniprotkb:B4DK71	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:sac1_human(display_long)|uniprotkb:SACM1L(gene name)|psi-mi:SACM1L(display_short)|uniprotkb:KIAA0851(gene name synonym)|uniprotkb:Suppressor of actin mutations 1-like protein(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)|uniprotkb:SAC1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034190|imex:IM-29092-47	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"refseq:XP_011531802.1|refseq:NP_054735.3|ensembl:ENSG00000211456.14(gene)|ensembl:ENST00000389061.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004438""(phosphatidylinositol-3-phosphate phosphatase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0016791""(phosphatase activity)|go:""GO:0034596""(phosphatidylinositol phosphate 4-phosphatase activity)|go:""GO:0043812""(phosphatidylinositol-4-phosphate phosphatase activity)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|go:""GO:0140268""(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR002013(Synaptojanin, N-terminal)|mint:Q9NTJ5|reactome:R-HSA-1483248|reactome:R-HSA-1660514|refseq:NP_001306001.1|refseq:NP_001306002.1|panther:PTHR45662(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:aaI+D/4SJcwZxWqoxDJ81dA60nU9606	intact-crc:0050DB4D49DAA10D|rigid:Fuf0+N9laHcWtOGRFjdeFsBB3Aw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:P62979	intact:EBI-13953897	intact:EBI-357375|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|ensembl:ENSP00000272317.6|ensembl:ENSP00000383981.3|ensembl:ENSP00000385659.1	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034190|imex:IM-29092-47	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1|ensembl:ENSG00000143947.15(gene)|ensembl:ENST00000272317.11(transcript)|ensembl:ENST00000402285.7(transcript)|ensembl:ENST00000404735.1(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006412""(translation)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019941""(modification-dependent protein catabolic process)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031386""(protein tag activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0032040""(small-subunit processome)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|interpro:IPR050158|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:5YDK|rcsb pdb:6DC6|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7BWD|rcsb pdb:7F0N|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|rcsb pdb:7MQ9|rcsb pdb:7MQA|rcsb pdb:7OOJ|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7WTT|rcsb pdb:7WTU|rcsb pdb:7WTV|rcsb pdb:7WTW|rcsb pdb:7WTX|rcsb pdb:7WTZ|rcsb pdb:7WU0|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8HTC|rcsb pdb:8HTF|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8IVB|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|rcsb pdb:9IPU|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866427|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-909733|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9680350|reactome:R-HSA-9683683|reactome:R-HSA-9692916|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-9725370|reactome:R-HSA-9735869|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-9754678|reactome:R-HSA-9755511|reactome:R-HSA-9758274|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9762114|reactome:R-HSA-977225|reactome:R-HSA-9824878|reactome:R-HSA-9828211|reactome:R-HSA-983168|reactome:R-HSA-9833109|reactome:R-HSA-9861718|panther:PTHR10666(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606	intact-crc:0050DB4D49DAA10D|rigid:Fuf0+N9laHcWtOGRFjdeFsBB3Aw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:Q9NP58	intact:EBI-13953897	intact:EBI-2115230|uniprotkb:O75542|uniprotkb:Q49A66|uniprotkb:Q59GQ5|uniprotkb:Q6ZME6|uniprotkb:Q96ME8|uniprotkb:Q9HAQ6|uniprotkb:Q9HAQ7|ensembl:ENSP00000265316.3	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:abcb6_human(display_long)|uniprotkb:ABCB6(gene name)|psi-mi:ABCB6(display_short)|uniprotkb:MTABC3(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:UMAT(gene name synonym)|uniprotkb:Mitochondrial ABC transporter 3(gene name synonym)|uniprotkb:Ubiquitously-expressed mammalian ABC half transporter(gene name synonym)|uniprotkb:P-glycoprotein-related protein(gene name synonym)|uniprotkb:ABC-type heme transporter ABCB6(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034190|imex:IM-29092-47	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"panther:PTHR24221(orthology-group)|ensembl:ENSG00000115657.14(gene)|ensembl:ENST00000265316.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005740""(mitochondrial envelope)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006778""(porphyrin-containing compound metabolic process)|go:""GO:0006779""(porphyrin-containing compound biosynthetic process)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007420""(brain development)|go:""GO:0015439""(ABC-type heme transporter activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:0015886""(heme transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0020037""(heme binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033013""(tetrapyrrole metabolic process)|go:""GO:0033162""(melanosome membrane)|go:""GO:0035351""(heme transmembrane transport)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0042168""(heme metabolic process)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|go:""GO:0043588""(skin development)|go:""GO:0046906""(tetrapyrrole binding)|go:""GO:0055085""(transmembrane transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098849""(cellular detoxification of cadmium ion)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:1903232""(melanosome assembly)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032410|interpro:IPR036640|interpro:IPR039421|mint:Q9NP58|rcsb pdb:3NH6|rcsb pdb:3NH9|rcsb pdb:3NHA|rcsb pdb:3NHB|rcsb pdb:7D7N|rcsb pdb:7D7R|rcsb pdb:7DNY|rcsb pdb:7DNZ|rcsb pdb:7EKL|rcsb pdb:7EKM|rcsb pdb:8FWK|rcsb pdb:8K7B|rcsb pdb:8K7C|rcsb pdb:8YR3|rcsb pdb:8YR4|reactome:R-HSA-1369007|reactome:R-HSA-5683371|refseq:NP_005680.1|efo:""Orphanet:241""|efo:""Orphanet:90044""|efo:""Orphanet:98938""|efo:""Orphanet:98942""|efo:""Orphanet:98943""|efo:""Orphanet:98944""|efo:""Orphanet:98945""|efo:""Orphanet:98946""|efo:""Orphanet:98947"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:3Zyw4d16oU1oT0eiAcOds3s1ZVQ9606	intact-crc:0050DB4D49DAA10D|rigid:Fuf0+N9laHcWtOGRFjdeFsBB3Aw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:A1L390	intact:EBI-13953897	intact:EBI-4401429|uniprotkb:A1L389|uniprotkb:B5MEC9|uniprotkb:O60339|uniprotkb:Q6GMS3|uniprotkb:Q6P4B1|uniprotkb:Q7L3S3|uniprotkb:Q86SW7|uniprotkb:Q8TEF5|uniprotkb:Q96EW6|uniprotkb:Q9BT82|intact:EBI-28970790|ensembl:ENSP00000247226.8	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:pkhg3_human(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034190|imex:IM-29092-47	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"refseq:XP_016876646.1|refseq:NP_001295076.1|ensembl:ENSG00000126822.18(gene)|ensembl:ENST00000247226.13(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0031267""(small GTPase binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:2000114""(regulation of establishment of cell polarity)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR043324|interpro:IPR055251|mint:A1L390|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013408|panther:PTHR45924(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:+obep09w4klmkB8i13aA5FQW2609606	intact-crc:0050DB4D49DAA10D|rigid:Fuf0+N9laHcWtOGRFjdeFsBB3Aw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:Q9UIQ6	intact:EBI-13953897	intact:EBI-2805360|uniprotkb:O00769|uniprotkb:Q9TNQ2|uniprotkb:Q9TNQ3|uniprotkb:Q9UIQ7|uniprotkb:Q59H76|uniprotkb:Q15145|ensembl:ENSP00000231368.5	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:lcap_human(display_long)|uniprotkb:OTASE(gene name synonym)|uniprotkb:Oxytocinase(gene name synonym)|uniprotkb:Insulin-regulated membrane aminopeptidase(gene name synonym)|uniprotkb:Insulin-responsive aminopeptidase(gene name synonym)|uniprotkb:Placental leucine aminopeptidase(gene name synonym)|uniprotkb:LNPEP(gene name)|psi-mi:LNPEP(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034190|imex:IM-29092-47	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"refseq:NP_005566.2|refseq:NP_787116.2|ensembl:ENSG00000113441.16(gene)|ensembl:ENST00000231368.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0002480""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007565""(female pregnancy)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0042277""(peptide binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|interpro:IPR045357|interpro:IPR050344|mint:Q9UIQ6|rcsb pdb:4P8Q|rcsb pdb:4PJ6|rcsb pdb:4Z7I|rcsb pdb:5C97|rcsb pdb:5JHQ|rcsb pdb:5MJ6|rcsb pdb:7ZYF|rcsb pdb:8CGP|rcsb pdb:8CGW|rcsb pdb:8P0I|reactome:R-HSA-1236977|reactome:R-HSA-1445148|reactome:R-HSA-983168|panther:PTHR11533(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:IOU7GW8f6aBYAjIUQXFKbU5Hqkw9606	intact-crc:0050DB4D49DAA10D|rigid:Fuf0+N9laHcWtOGRFjdeFsBB3Aw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:Q9H2H9	intact:EBI-13953897	intact:EBI-9978441|uniprotkb:Q8NC61|uniprotkb:Q8NCF8|uniprotkb:Q96JX2|uniprotkb:Q9H2Q2|ensembl:ENSP00000381634.4|ensembl:ENSP00000398142.1|ensembl:ENSP00000447853.1|ensembl:ENSP00000449607.1	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:s38a1_human(display_long)|uniprotkb:SLC38A1(gene name)|psi-mi:SLC38A1(display_short)|uniprotkb:ATA1(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:SAT1(gene name synonym)|uniprotkb:SNAT1(gene name synonym)|uniprotkb:Amino acid transporter A1(gene name synonym)|uniprotkb:N-system amino acid transporter 2(gene name synonym)|uniprotkb:Solute carrier family 38 member 1(gene name synonym)|uniprotkb:System A amino acid transporter 1(gene name synonym)|uniprotkb:System N amino acid transporter 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034190|imex:IM-29092-47	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"refseq:NP_001070952.1|refseq:NP_001265316.1|refseq:NP_001265317.1|refseq:NP_001265318.1|refseq:NP_109599.3|ensembl:ENSG00000111371.16(gene)|ensembl:ENST00000398637.10(transcript)|ensembl:ENST00000439706.5(transcript)|ensembl:ENST00000546893.5(transcript)|ensembl:ENST00000549049.5(transcript)|go:""GO:0001504""(neurotransmitter uptake)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005283""(""amino acid:sodium symporter activity"")|go:""GO:0005295""(""neutral L-amino acid:sodium symporter activity"")|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0006865""(amino acid transport)|go:""GO:0006868""(glutamine transport)|go:""GO:0007565""(female pregnancy)|go:""GO:0009449""(gamma-aminobutyric acid biosynthetic process)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015186""(L-glutamine transmembrane transporter activity)|go:""GO:0015375""(""glycine:sodium symporter activity"")|go:""GO:0015655""(""alanine:sodium symporter activity"")|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0032228""(regulation of synaptic transmission, GABAergic)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043090""(amino acid import)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098591""(external side of apical plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901036""(positive regulation of L-glutamine import across plasma membrane)|go:""GO:1902475""(L-alpha-amino acid transmembrane transport)|interpro:IPR013057(Amino acid transporter, transmembrane)|mint:Q9H2H9|reactome:R-HSA-210455|reactome:R-HSA-352230|panther:PTHR22950(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:bywv401DbQBHRZvcPc8o8mp8nfE9606	intact-crc:0050DB4D49DAA10D|rigid:Fuf0+N9laHcWtOGRFjdeFsBB3Aw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:P04114	intact:EBI-13953897	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242.1	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034190|imex:IM-29092-47	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"ensembl:ENSG00000084674.15(gene)|ensembl:ENST00000233242.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006642""(triglyceride mobilization)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007399""(nervous system development)|go:""GO:0008201""(heparin binding)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0009566""(fertilization)|go:""GO:0009615""(response to virus)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010886""(positive regulation of cholesterol storage)|go:""GO:0019433""(triglyceride catabolic process)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031904""(endosome lumen)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0034359""(mature chylomicron)|go:""GO:0034360""(chylomicron remnant)|go:""GO:0034361""(very-low-density lipoprotein particle)|go:""GO:0034362""(low-density lipoprotein particle)|go:""GO:0034363""(intermediate-density lipoprotein particle)|go:""GO:0034374""(low-density lipoprotein particle remodeling)|go:""GO:0034379""(very-low-density lipoprotein particle assembly)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0035473""(lipase binding)|go:""GO:0042158""(lipoprotein biosynthetic process)|go:""GO:0042159""(lipoprotein catabolic process)|go:""GO:0042627""(chylomicron)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045540""(regulation of cholesterol biosynthetic process)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0071402""(cellular response to lipoprotein particle stimulus)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0120020""(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015817(Vitellinogen, open beta-sheet, subdomain 1)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|interpro:IPR052418|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-5686938|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|refseq:NP_000375.2|dip:DIP-44767N|efo:""Orphanet:391665""|panther:PTHR13769(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:KDfhejl4P+qI4MIoZEYk2ZnvMUY9606	intact-crc:0050DB4D49DAA10D|rigid:Fuf0+N9laHcWtOGRFjdeFsBB3Aw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:O95373	intact:EBI-13953897	intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|ensembl:ENSP00000369042.3|intact:EBI-28976968	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034190|imex:IM-29092-47	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"ensembl:ENSG00000205339.10(gene)|ensembl:ENST00000379719.8(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0016020""(membrane)|go:""GO:0030695""(GTPase regulator activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0042393""(histone binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045736""(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0046332""(SMAD binding)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1901331""(positive regulation of odontoblast differentiation)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373|refseq:NP_006382.1|dip:DIP-32574N|panther:PTHR10997(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606	intact-crc:0050DB4D49DAA10D|rigid:Fuf0+N9laHcWtOGRFjdeFsBB3Aw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:P02786	intact:EBI-13953897	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224.4|ensembl:ENSP00000376197.3|ensembl:ENSP00000513646.1|ensembl:ENSP00000513654.1	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034190|imex:IM-29092-47	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"efo:""Orphanet:476113""|ensembl:ENSG00000072274.14(gene)|ensembl:ENST00000360110.9(transcript)|ensembl:ENST00000392396.7(transcript)|ensembl:ENST00000698280.1(transcript)|ensembl:ENST00000698291.1(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004998""(transferrin receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010039""(response to iron ion)|go:""GO:0010042""(response to manganese ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010637""(negative regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033572""(transferrin transport)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0046688""(response to copper ion)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0072562""(blood microparticle)|go:""GO:0098944""(postsynaptic recycling endosome membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|interpro:IPR046450|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|rcsb pdb:7ZQS|rcsb pdb:8P0Z|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9725554|refseq:NP_001121620.1|refseq:NP_001300894.1|refseq:NP_001300895.1|refseq:NP_003225.2|dip:DIP-2736N|panther:PTHR10404(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	intact-crc:0050DB4D49DAA10D|rigid:Fuf0+N9laHcWtOGRFjdeFsBB3Aw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B423	uniprotkb:P22059	intact:EBI-13953897	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	psi-mi:a0a0f6b423_salt1(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM14_2824(locus name)	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034190|imex:IM-29092-47	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR054328|interpro:IPR054329|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|mint:A0A0F6B423"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/01	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg588858	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	intact-crc:0050DB4D49DAA10D|rigid:Fuf0+N9laHcWtOGRFjdeFsBB3Aw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q8N163	intact:EBI-27033646	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|uniprotkb:B2RB79|uniprotkb:D3DSR6|ensembl:ENSP00000310670.4|ensembl:ENSP00000373930.3	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_066997.3|ensembl:ENSG00000158941.17(gene)|ensembl:ENST00000308511.9(transcript)|ensembl:ENST00000389279.7(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005819""(spindle)|go:""GO:0006397""(mRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0008380""(RNA splicing)|go:""GO:0009411""(response to UV)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032784""(regulation of DNA-templated transcription elongation)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0044609""(DBIRD complex)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048511""(rhythmic process)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090311""(regulation of protein deacetylation)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:2000003""(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR045353|interpro:IPR045354|mint:Q8N163|rcsb pdb:8EZ6|reactome:R-HSA-3371453|dip:DIP-38122N"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q9NX95	intact:EBI-27033646	intact:EBI-948293|uniprotkb:B3KU61|uniprotkb:B3KQX3|uniprotkb:A8K354|uniprotkb:Q5R1T1|uniprotkb:Q5R1T2|uniprotkb:Q5R1T3|uniprotkb:Q5Y2M6|uniprotkb:Q8ND49|uniprotkb:Q8TCR6|uniprotkb:Q9P256|intact:EBI-1019860|uniprotkb:Q96D80|ensembl:ENSP00000276646.9|ensembl:ENSP00000386154.2|ensembl:ENSP00000403544.1|ensembl:ENSP00000404369.1|ensembl:ENSP00000407118.1|ensembl:ENSP00000434679.1	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:sybu_human(display_long)|uniprotkb:SYBU(gene name)|psi-mi:SYBU(display_short)|uniprotkb:GOLSYN(gene name synonym)|uniprotkb:KIAA1472(gene name synonym)|uniprotkb:Syntaxin-1-binding protein(gene name synonym)|uniprotkb:Golgi-localized syntaphilin-related protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_001093213.1|refseq:NP_001093214.1|refseq:NP_001093215.1|refseq:NP_001093216.1|refseq:NP_001093217.1|refseq:NP_001093218.1|refseq:NP_001093219.1|refseq:NP_001093220.1|refseq:NP_001093221.1|refseq:NP_001093222.1|refseq:NP_001093223.1|refseq:NP_001093224.1|refseq:NP_001093225.1|refseq:NP_001093226.1|refseq:NP_060256.3|refseq:NP_001317525.1|refseq:XP_016869103.1|refseq:XP_016869104.1|ensembl:ENSG00000147642.17(gene)|ensembl:ENST00000276646.14(transcript)|ensembl:ENST00000408908.6(transcript)|ensembl:ENST00000422135.5(transcript)|ensembl:ENST00000433638.1(transcript)|ensembl:ENST00000440310.5(transcript)|ensembl:ENST00000533171.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0019896""(axonal transport of mitochondrion)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060025""(regulation of synaptic activity)|go:""GO:0060074""(synapse maturation)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990048""(anterograde neuronal dense core vesicle transport)|interpro:IPR028197|mint:Q9NX95|panther:PTHR16208(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:KD7Qn1H+FtUBGWUXnk5b9ARH23Y9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q9BUJ2	intact:EBI-27033646	intact:EBI-1018153|intact:EBI-2563529|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_008971.2|refseq:NP_653333.1|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N|ensembl:ENSG00000105323.18(gene)|ensembl:ENST00000392006.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006396""(RNA processing)|go:""GO:0009615""(response to virus)|go:""GO:0019899""(enzyme binding)|go:""GO:0045202""(synapse)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|rcsb pdb:1ZRJ|panther:PTHR12381(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:IahA7SVR1NmvldrWKQlAwApinQE9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q6PKG0	intact:EBI-27033646	intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_056130.2|refseq:XP_005268461.1|ensembl:ENSG00000155506.19(gene)|ensembl:ENST00000518297.6(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0008190""(eukaryotic initiation factor 4E binding)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008494""(translation activator activity)|rcsb pdb:5C0V|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0031929""(TOR signaling)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0072752""(cellular response to rapamycin)|go:""GO:1990928""(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3|rcsb pdb:7SOO|rcsb pdb:7SOP|rcsb pdb:7SOQ|rcsb pdb:7SOR|rcsb pdb:7SOS|rcsb pdb:7SOT|rcsb pdb:7SOU|rcsb pdb:7SOV|rcsb pdb:7SOW|rcsb pdb:8EY6|rcsb pdb:8EY7|rcsb pdb:8EY8|rcsb pdb:8G90|rcsb pdb:8G91|reactome:R-HSA-9705671|panther:PTHR22792(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q15208	intact:EBI-27033646	intact:EBI-458376|uniprotkb:Q503A1|intact:EBI-25629237|ensembl:ENSP00000229812.7	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:stk38_human(display_long)|uniprotkb:NDR1(gene name synonym)|uniprotkb:STK38(gene name)|psi-mi:STK38(display_short)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_009202.1|refseq:XP_006715051.1|refseq:XP_006715052.1|refseq:NP_001292031.1|panther:PTHR24356(orthology-group)|ensembl:ENSG00000112079.9(gene)|ensembl:ENST00000229812.8(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006974""(DNA damage response)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035861""(site of double-strand break)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036211""(protein modification process)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099173""(postsynapse organization)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140035""(ubiquitin-like protein reader activity)|go:""GO:0140566""(histone reader activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:0141185""(UFM1-modified protein reader activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR050839|mint:Q15208|rcsb pdb:1PSB|rcsb pdb:6BXI|reactome:R-HSA-9013418|reactome:R-HSA-9013422|ensembl:ENSP00000229812.7"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:YHzdDrPEH6YdhOXtcnLWArqftck9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q14CZ7	intact:EBI-27033646	intact:EBI-10234819|uniprotkb:Q9BVD3|ensembl:ENSP00000264669.5	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:fakd3_human(display_long)|uniprotkb:FASTKD3(gene name)|psi-mi:FASTKD3(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_076996.2|refseq:XP_006714561.1|panther:PTHR21228(orthology-group)|ensembl:ENSG00000124279.12(gene)|ensembl:ENST00000264669.10(transcript)|go:""GO:0000963""(mitochondrial RNA processing)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0033617""(mitochondrial cytochrome c oxidase assembly)|go:""GO:0035770""(ribonucleoprotein granule)|go:""GO:0044528""(regulation of mitochondrial mRNA stability)|go:""GO:0070131""(positive regulation of mitochondrial translation)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|interpro:IPR050870|mint:Q14CZ7"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:MhzRoSmzPBUZ43yeB5FNrvjbszo9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q8NHQ1	intact:EBI-27033646	intact:EBI-739624|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8|ensembl:ENSP00000264982.3|ensembl:ENSP00000419231.1	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_077817.2|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|ensembl:ENSG00000114107.9(gene)|ensembl:ENST00000264982.8(transcript)|ensembl:ENST00000484888.5(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0042802""(identical protein binding)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0060271""(cilium assembly)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_016862764.1|panther:PTHR14594(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q9Y421	intact:EBI-27033646	intact:EBI-726146|uniprotkb:Q9BT02|ensembl:ENSP00000263384.6	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:fa32a_human(display_long)|uniprotkb:FAM32A(gene name)|psi-mi:FAM32A(display_short)|uniprotkb:OTAG12(gene name synonym)|uniprotkb:Ovarian tumor-associated gene 12(gene name synonym)|uniprotkb:CGI-144(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_054796.1|ensembl:ENSG00000105058.12(gene)|ensembl:ENST00000263384.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006915""(apoptotic process)|interpro:IPR013865(Protein of unknown function DUF1754, eukaryotic)|mint:Q9Y421|rcsb pdb:6QDV|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:9FMD|reactome:R-HSA-72163|panther:PTHR13282(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:c3pfvC7jOfekPCI13pXodImGcJs9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q9UN81	intact:EBI-27033646	intact:EBI-722458|intact:EBI-8874490|uniprotkb:Q15605	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:lorf1_human(display_long)|uniprotkb:L1RE1(gene name)|psi-mi:L1RE1(display_short)|uniprotkb:LINE retrotransposable element 1(gene name synonym)|uniprotkb:LINE1 retrotransposable element 1(gene name synonym)|uniprotkb:LRE1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"mint:Q9UN81|go:""GO:0000166""(nucleotide binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0032197""(retrotransposition)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004244(Transposase, L1)|interpro:IPR035300|interpro:IPR035301|interpro:IPR042566|interpro:IPR043636|rcsb pdb:2LDY|rcsb pdb:2W7A|rcsb pdb:2YKO|rcsb pdb:2YKP|rcsb pdb:2YKQ|rcsb pdb:6FIA|dip:DIP-48676N|panther:PTHR11505(orthology-group)"	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:C9ED80C33ED37523	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:pefRokDO38574Jo5bl2/49LYvaQ9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:P40926	intact:EBI-27033646	intact:EBI-721232|uniprotkb:O43682|uniprotkb:B4DE44|uniprotkb:E9PDB2|uniprotkb:A8K414|uniprotkb:B2RE78|ensembl:ENSP00000327070.5	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:mdhm_human(display_long)|uniprotkb:MDH2(gene name)|psi-mi:MDH2(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"efo:""Orphanet:29072""|ensembl:ENSG00000146701.12(gene)|ensembl:ENST00000315758.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006108""(malate metabolic process)|go:""GO:0006734""(NADH metabolic process)|go:""GO:0009060""(aerobic respiration)|go:""GO:0016020""(membrane)|go:""GO:0030060""(""L-malate dehydrogenase (NAD+) activity"")|go:""GO:0042802""(identical protein binding)|go:""GO:0043490""(malate-aspartate shuttle)|go:""GO:0046554""(""L-malate dehydrogenase (NADP+) activity"")|go:""GO:0070062""(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010097(Malate dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P40926|rcsb pdb:2DFD|rcsb pdb:4WLE|rcsb pdb:4WLF|rcsb pdb:4WLN|rcsb pdb:4WLO|rcsb pdb:4WLU|rcsb pdb:4WLV|reactome:R-HSA-71403|reactome:R-HSA-9837999|reactome:R-HSA-9856872|refseq:NP_001269332.1|refseq:NP_001269333.1|refseq:NP_005909.2|panther:PTHR11540(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:Ur2aO+2M7e/ftD8RlhPMHBc8/JU9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:P05455	intact:EBI-27033646	intact:EBI-358037|uniprotkb:Q15367|uniprotkb:Q53XJ4|ensembl:ENSP00000260956.4|ensembl:ENSP00000386636.1	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"panther:PTHR22792(orthology-group)|refseq:NP_003133.1|ensembl:ENSG00000138385.16(gene)|ensembl:ENST00000260956.9(transcript)|ensembl:ENST00000409333.1(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0001682""(tRNA 5'-leader removal)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006400""(tRNA modification)|go:""GO:0006409""(tRNA export from nucleus)|go:""GO:0008033""(tRNA processing)|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008334""(histone mRNA metabolic process)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0042780""(tRNA 3'-end processing)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0071045""(nuclear histone mRNA catabolic process)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1990825""(sequence-specific mRNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476|refseq:NP_001281074.1|dip:DIP-29750N"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:O95263	intact:EBI-27033646	intact:EBI-11603452|uniprotkb:Q86XK8|uniprotkb:Q8N3T2|uniprotkb:Q5J7V7|uniprotkb:Q8IUJ7|uniprotkb:Q8IUJ9|uniprotkb:Q8IUJ8|uniprotkb:Q8IUK0|ensembl:ENSP00000264917.6	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:pde8b_human(display_long)|uniprotkb:PDE8B(gene name)|psi-mi:PDE8B(display_short)|uniprotkb:Cell proliferation-inducing gene 22 protein(gene name synonym)|uniprotkb:PIG22(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"efo:""Orphanet:228169""|panther:PTHR11347(orthology-group)|ensembl:ENSG00000113231.14(gene)|ensembl:ENST00000264917.10(transcript)|go:""GO:0001662""(behavioral fear response)|go:""GO:0004115""(3',5'-cyclic-AMP phosphodiesterase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006198""(cAMP catabolic process)|go:""GO:0008542""(visual learning)|go:""GO:0019933""(cAMP-mediated signaling)|go:""GO:0035106""(operant conditioning)|go:""GO:0046872""(metal ion binding)|go:""GO:0047555""(3',5'-cyclic-GMP phosphodiesterase activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0061179""(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090032""(negative regulation of steroid hormone biosynthetic process)|interpro:IPR000014(PAS)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR013938(3'5'-cyclic nucleotide phosphodiesterase PDE8)|interpro:IPR023088|interpro:IPR023174|interpro:IPR035965|interpro:IPR036971|mint:O95263|reactome:R-HSA-418555|refseq:NP_001025022.1|refseq:NP_001025023.1|refseq:NP_001025024.1|refseq:NP_001025025.1|refseq:NP_003710.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:VdMjxtzjSSucRCXecbv2aDlK5Qg9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q12849	intact:EBI-27033646	intact:EBI-1054150|uniprotkb:Q6ZST3|uniprotkb:Q8NBD2|uniprotkb:Q4W5S5|uniprotkb:Q8IWD6|uniprotkb:B3KPW0|intact:EBI-28981368|ensembl:ENSP00000254799.6	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:grsf1_human(display_long)|uniprotkb:GRSF1(gene name)|psi-mi:GRSF1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_002083.3|refseq:NP_001091947.1|refseq:XP_011530199.1|ensembl:ENSG00000132463.15(gene)|ensembl:ENST00000254799.11(transcript)|go:""GO:0000957""(mitochondrial RNA catabolic process)|go:""GO:0000962""(positive regulation of mitochondrial RNA catabolic process)|go:""GO:0002151""(G-quadruplex RNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006397""(mRNA processing)|go:""GO:0008033""(tRNA processing)|go:""GO:0009952""(anterior/posterior pattern specification)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0035770""(ribonucleoprotein granule)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034424|interpro:IPR034425|interpro:IPR034426|interpro:IPR035979|interpro:IPR050666|mint:Q12849|rcsb pdb:2LMI|rcsb pdb:4QU6|rcsb pdb:4QU7|reactome:R-HSA-192823|reactome:R-HSA-9836573|panther:PTHR13976(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:89Xul87okYruMW1PQtPMbBTqX+09606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q8WVV9	intact:EBI-27033646	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625.3	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_001136122.1|refseq:NP_612403.2|panther:PTHR15592(orthology-group)|ensembl:ENSG00000143889.16(gene)|ensembl:ENST00000449105.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006397""(mRNA processing)|go:""GO:0016020""(membrane)|go:""GO:0033120""(positive regulation of RNA splicing)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045202""(synapse)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|interpro:IPR034985|interpro:IPR034986|interpro:IPR034987|interpro:IPR035979|mint:Q8WVV9|rcsb pdb:7EVS"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q53R41	intact:EBI-27033646	intact:EBI-3957005|uniprotkb:Q8N583|uniprotkb:Q8TEA9|uniprotkb:Q96JM5|uniprotkb:Q96N71|uniprotkb:Q9H6T4|ensembl:ENSP00000400513.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:fakd1_human(display_long)|uniprotkb:FASTKD1(gene name)|psi-mi:FASTKD1(display_short)|uniprotkb:KIAA1800(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_078898.3|refseq:NP_001268405.1|refseq:NP_001308975.1|refseq:NP_001308977.1|refseq:NP_001308978.1|ensembl:ENSG00000138399.18(gene)|ensembl:ENST00000453153.7(transcript)|go:""GO:0000959""(mitochondrial RNA metabolic process)|go:""GO:0000963""(mitochondrial RNA processing)|go:""GO:0003723""(RNA binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0035770""(ribonucleoprotein granule)|go:""GO:0044528""(regulation of mitochondrial mRNA stability)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|interpro:IPR050870|mint:Q53R41|refseq:XP_016860400.1|panther:PTHR21228(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:eizlBY2w9CXu4y4WE8R4QOUWoXA9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q96DG6	intact:EBI-27033646	intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658.3	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_620164.1|refseq:XP_016864523.1|refseq:XP_016864524.1|ensembl:ENSG00000164237.9(gene)|ensembl:ENST00000296658.4(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0016787""(hydrolase activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|panther:PTHR46812(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q96I24	intact:EBI-27033646	intact:EBI-954200|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8|ensembl:ENSP00000318177.9|intact:EBI-21357206	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_003925.1|dip:DIP-50124N|ensembl:ENSG00000107164.17(gene)|ensembl:ENST00000319725.10(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005840""(ribosome)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043198""(dendritic shaft)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|panther:PTHR10288(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q13310	intact:EBI-27033646	intact:EBI-372844|uniprotkb:Q6P0N3|ensembl:ENSP00000361948.3|uniprotkb:B1ANQ8|intact:EBI-877641|uniprotkb:Q4VC03	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	"psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:""Inducible poly(A)-binding protein""(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621.15(gene)|ensembl:ENST00000372857.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0006401""(RNA catabolic process)|go:""GO:0006412""(translation)|go:""GO:0007596""(blood coagulation)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0061515""(myeloid cell development)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034364|interpro:IPR035979|interpro:IPR036053|interpro:IPR045305|mint:Q13310|refseq:NP_001129125.1|panther:PTHR24012(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q92615	intact:EBI-27033646	intact:EBI-1052558|uniprotkb:Q5T3R3|uniprotkb:Q5T3R4|uniprotkb:Q5T3R5|uniprotkb:Q68CY4|uniprotkb:A7MD20|intact:EBI-28969094|ensembl:ENSP00000326128.3	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:lar4b_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:LARP4B(gene name)|psi-mi:LARP4B(display_short)|uniprotkb:LARP5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym)|uniprotkb:KIAA0217(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_055970.1|ensembl:ENSG00000107929.16(gene)|ensembl:ENST00000316157.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0045727""(positive regulation of translation)|go:""GO:1905870""(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034900|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:Q92615|rcsb pdb:3PTH|panther:PTHR22792(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:tVFpPu0vhCgdRt0lowfi5GzA8Do9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q9NZB2	intact:EBI-27033646	intact:EBI-1171960|uniprotkb:A6NGU0|uniprotkb:O60649|uniprotkb:Q14688|uniprotkb:Q4VXF4|uniprotkb:Q4VXF5|uniprotkb:Q4VXG2|uniprotkb:Q96I21|uniprotkb:Q9NZB1|uniprotkb:C4AMC6|uniprotkb:Q86V69|intact:EBI-2560129|ensembl:ENSP00000277165.5	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:f120a_human(display_long)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:Oxidative stress-associated SRC activator(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_055427.2|refseq:XP_011516714.1|refseq:NP_001273651.1|refseq:NP_001273652.1|refseq:NP_001273653.1|panther:PTHR15976(orthology-group)|ensembl:ENSG00000048828.18(gene)|ensembl:ENST00000277165.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q9NZB2"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q9HCE1	intact:EBI-27033646	intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028.2|ensembl:ENSP00000358659.1|ensembl:ENSP00000399797.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|ensembl:ENSG00000155363.19(gene)|ensembl:ENST00000357443.2(transcript)|ensembl:ENST00000369645.6(transcript)|ensembl:ENST00000413052.6(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010526""(transposable element silencing)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032574""(5'-3' RNA helicase activity)|go:""GO:0035194""(regulatory ncRNA-mediated post-transcriptional gene silencing)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035279""(miRNA-mediated gene silencing by mRNA destabilization)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0043186""(P granule)|go:""GO:0051607""(defense response to virus)|go:""GO:0061014""(positive regulation of mRNA catabolic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:0141008""(transposable element silencing by mRNA destabilization)|go:""GO:0150011""(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|interpro:IPR047187|interpro:IPR049075|interpro:IPR049077|interpro:IPR049079|interpro:IPR049080|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9725371|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001308253.1|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1|panther:PTHR10887(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q9UH99	intact:EBI-27033646	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|uniprotkb:B0QY62|uniprotkb:Q504T5|ensembl:ENSP00000383992.1|ensembl:ENSP00000385740.1|ensembl:ENSP00000508608.1	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|ensembl:ENSG00000100242.16(gene)|ensembl:ENST00000405510.5(transcript)|ensembl:ENST00000406622.5(transcript)|ensembl:ENST00000689035.1(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0008017""(microtubule binding)|go:""GO:0010008""(endosome membrane)|go:""GO:0021817""(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031022""(nuclear migration along microfilament)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034993""(meiotic nuclear membrane microtubule tethering complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0051642""(centrosome localization)|go:""GO:0090292""(nuclear matrix anchoring at nuclear membrane)|go:""GO:0140444""(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR040994|interpro:IPR045119|mint:Q9UH99|rcsb pdb:3UNP|rcsb pdb:4DXR|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|panther:PTHR12911(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q8N3C0	intact:EBI-27033646	intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249.14(gene)|ensembl:ENST00000369162.7(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006307""(DNA alkylation repair)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0043138""(3'-5' DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0099053""(obsolete activating signal cointegrator 1 complex)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990116""(ribosome-associated ubiquitin-dependent protein catabolic process)|go:""GO:1990391""(DNA repair complex)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR050474|mint:Q8N3C0|rcsb pdb:6YXQ|rcsb pdb:8ALZ|reactome:R-HSA-112126|panther:PTHR24075(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q9NWU5	intact:EBI-27033646	intact:EBI-5461867|uniprotkb:Q5H9Q1|uniprotkb:Q96Q51|uniprotkb:Q9P006|intact:EBI-6137918|uniprotkb:A6NGJ8|ensembl:ENSP00000431040.1	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:rm22_human(display_long)|uniprotkb:MRPL22(gene name)|psi-mi:MRPL22(display_short)|uniprotkb:MRPL25(gene name synonym)|uniprotkb:RPML25(gene name synonym)|uniprotkb:39S ribosomal protein L25, mitochondrial(gene name synonym)|uniprotkb:HSPC158(orf name)|uniprotkb:39S ribosomal protein L22, mitochondrial(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_001014990.1|refseq:NP_054899.2|ensembl:ENSG00000082515.18(gene)|ensembl:ENST00000523037.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005762""(mitochondrial large ribosomal subunit)|go:""GO:0006412""(translation)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR036394|interpro:IPR047867|mint:Q9NWU5|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:7OI6|rcsb pdb:7OI7|rcsb pdb:7OI8|rcsb pdb:7OI9|rcsb pdb:7OIA|rcsb pdb:7OIB|rcsb pdb:7OIC|rcsb pdb:7OID|rcsb pdb:7OIE|rcsb pdb:7PD3|rcsb pdb:7PO4|rcsb pdb:7QH6|rcsb pdb:7QH7|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8OIR|rcsb pdb:8OIT|rcsb pdb:8PK0|rcsb pdb:8QSJ|rcsb pdb:8QU1|rcsb pdb:8QU5|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR13501(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:Nmwjb2QTu0IyJMS0SufI3PsBwmM9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q9Y5B6	intact:EBI-27033646	intact:EBI-2557602|uniprotkb:Q9NYQ0|uniprotkb:Q96DU8|uniprotkb:D3DSE7|ensembl:ENSP00000328992.4|ensembl:ENSP00000458262.2|ensembl:ENSP00000458892.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:paxb1_human(display_long)|uniprotkb:PAXBP1(gene name)|psi-mi:PAXBP1(display_short)|uniprotkb:C21orf66(gene name synonym)|uniprotkb:GC-rich sequence DNA-binding factor 1(gene name synonym)|uniprotkb:GCFC(gene name synonym)|uniprotkb:GCFC1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_037461.2|refseq:NP_057715.2|ensembl:ENSG00000159086.15(gene)|ensembl:ENSG00000263141.5(gene)|ensembl:ENST00000331923.9(transcript)|ensembl:ENST00000573680.5(transcript)|ensembl:ENST00000574159.2(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007517""(muscle organ development)|go:""GO:0014842""(regulation of skeletal muscle satellite cell proliferation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1990226""(histone methyltransferase binding)|go:""GO:2000288""(positive regulation of myoblast proliferation)|interpro:IPR012890(GC-rich sequence DNA-binding factor-like)|interpro:IPR022783|mint:Q9Y5B6|rcsb pdb:8RO2|panther:PTHR12214(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:SYrCt+PvgtLbYgHiN2ZP7yPEnIk9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:O95466	intact:EBI-27033646	intact:EBI-720020|uniprotkb:Q6DKG5|uniprotkb:Q6IBP3|uniprotkb:Q86UH1|uniprotkb:Q8N671|uniprotkb:Q8TDH1|uniprotkb:Q96H10|uniprotkb:D2DGW2|ensembl:ENSP00000329219.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:fmnl1_human(display_long)|uniprotkb:Leukocyte formin(gene name synonym)|uniprotkb:CLL-associated antigen KW-13(gene name synonym)|uniprotkb:FMNL1(gene name)|psi-mi:FMNL1(display_short)|uniprotkb:C17orf1(gene name synonym)|uniprotkb:C17orf1B(gene name synonym)|uniprotkb:FMNL(gene name synonym)|uniprotkb:FRL1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.68	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_005883.2|ensembl:ENSG00000184922.15(gene)|ensembl:ENST00000331495.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032059""(bleb)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR043592|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:O95466|rcsb pdb:4YDH|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:XP_006722126.1|refseq:XP_006722133.1|panther:PTHR45857(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:SN1xgeqb5yPUjiaEv2H/kyDrD4c9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:O00767	intact:EBI-27033646	intact:EBI-2684237|uniprotkb:Q5W037|uniprotkb:B2R5U0|uniprotkb:Q96KF6|uniprotkb:Q53GR9|uniprotkb:Q9Y695|uniprotkb:Q9BS07|uniprotkb:Q16150|uniprotkb:Q6GSS4|uniprotkb:Q5W038|uniprotkb:D3DR68|ensembl:ENSP00000359380.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	"psi-mi:scd_human(display_long)|uniprotkb:""Delta(9)-desaturase""(gene name synonym)|uniprotkb:Fatty acid desaturase(gene name synonym)|uniprotkb:Acyl-CoA desaturase(gene name synonym)|uniprotkb:FADS5(gene name synonym)|uniprotkb:SCD1(gene name synonym)|uniprotkb:SCDOS(gene name synonym)|uniprotkb:SCD(gene name)|psi-mi:SCD(display_short)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_005054.3|ensembl:ENSG00000099194.6(gene)|ensembl:ENST00000370355.3(transcript)|go:""GO:0004768""(stearoyl-CoA 9-desaturase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006636""(unsaturated fatty acid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0032896""(palmitoyl-CoA 9-desaturase activity)|go:""GO:0070542""(response to fatty acid)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1903966""(monounsaturated fatty acid biosynthetic process)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|mint:O00767|rcsb pdb:4ZYO|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|reactome:R-HSA-9841922|panther:PTHR11351(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:GeF7PMgZb07js39m6ykSSmFuIUA9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:D0ZIB5	uniprotkb:Q8WUY3	intact:EBI-27033646	intact:EBI-743880|intact:EBI-28967347|uniprotkb:Q5T304|uniprotkb:B4DQH8|uniprotkb:O15073|uniprotkb:Q58A63|uniprotkb:Q5T476|uniprotkb:Q6T2V6|uniprotkb:Q6T2V7|uniprotkb:Q8N665|uniprotkb:Q5JUB6|uniprotkb:B3KYC4|ensembl:ENSP00000365908.3	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:prun2_human(display_long)|uniprotkb:PRUNE2(gene name)|psi-mi:PRUNE2(display_short)|uniprotkb:C9orf65(gene name synonym)|uniprotkb:BMCC1(gene name synonym)|uniprotkb:BNIPXL(gene name synonym)|uniprotkb:KIAA0367(gene name synonym)|uniprotkb:BNIP2 motif-containing molecule at the C-terminal region 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27034209|imex:IM-29092-87	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_056040.2|refseq:NP_001294976.1|refseq:NP_001294977.1|refseq:NP_001294978.1|refseq:NP_001294979.1|refseq:NP_001294980.1|refseq:XP_011516625.1|ensembl:ENSG00000106772.19(gene)|ensembl:ENST00000376718.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0016462""(pyrophosphatase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR004097(DHHA2)|interpro:IPR022181|interpro:IPR036865|interpro:IPR038222|interpro:IPR038763|mint:Q8WUY3|panther:PTHR12112(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:rK1uzBXTEpJHKZ6p6Y0EgfdLibw9606	intact-crc:31A2CD3CDB764218|rigid:cst3aozrOn5pZluVqolg9NeK1Ik	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P16070	intact:EBI-10760263	intact:EBI-490245|ensembl:ENSP00000398632.2|uniprotkb:P22511|uniprotkb:Q04858|uniprotkb:Q13419|uniprotkb:Q13957|uniprotkb:Q13958|uniprotkb:Q13959|uniprotkb:Q13960|uniprotkb:Q13961|uniprotkb:Q13967|uniprotkb:Q13968|uniprotkb:Q13980|uniprotkb:Q15861|uniprotkb:Q16064|uniprotkb:Q16065|uniprotkb:Q16066|uniprotkb:Q16208|uniprotkb:Q16522|uniprotkb:Q86T72|uniprotkb:Q86Z27|uniprotkb:Q8N694|uniprotkb:Q92493|uniprotkb:Q96J24|uniprotkb:Q9UJ36|uniprotkb:Q9H5A5|uniprotkb:A5YRN9|uniprotkb:Q9UC28|uniprotkb:Q9UC29|uniprotkb:Q9UC30|uniprotkb:Q9UCB0|uniprotkb:D3DR12|uniprotkb:D3DR13|uniprotkb:B6EAT9|uniprotkb:O95370	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:cd44_human(display_long)|uniprotkb:Epican(gene name synonym)|uniprotkb:CDw44(gene name synonym)|uniprotkb:Phagocytic glycoprotein I(gene name synonym)|uniprotkb:Extracellular matrix receptor III(gene name synonym)|uniprotkb:HUTCH-I(gene name synonym)|uniprotkb:Phagocytic glycoprotein 1(gene name synonym)|uniprotkb:GP90 lymphocyte homing/adhesion receptor(gene name synonym)|uniprotkb:Hermes antigen(gene name synonym)|uniprotkb:Hyaluronate receptor(gene name synonym)|uniprotkb:Heparan sulfate proteoglycan(gene name synonym)|uniprotkb:CD44(gene name)|psi-mi:CD44(display_short)|uniprotkb:LHR(gene name synonym)|uniprotkb:MDU2(gene name synonym)|uniprotkb:MDU3(gene name synonym)|uniprotkb:MIC4(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036865|imex:IM-29092-144	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0009986""(cell surface)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|ensembl:ENSG00000026508.21(gene)|ensembl:ENST00000428726.8(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005540""(hyaluronic acid binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005925""(focal adhesion)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0016477""(cell migration)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042995""(cell projection)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0051216""(cartilage development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070487""(monocyte aggregation)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:1900625""(positive regulation of monocyte aggregation)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000392""(regulation of lamellipodium morphogenesis)|interpro:IPR000538(Link)|interpro:IPR001231(CD44 antigen)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR043210|mint:P16070|rcsb pdb:1POZ|rcsb pdb:1UUH|rcsb pdb:2I83|rcsb pdb:4PZ3|rcsb pdb:4PZ4|rcsb pdb:6TXS|reactome:R-HSA-1474228|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2160916|reactome:R-HSA-6798695|reactome:R-HSA-877300|refseq:NP_000601.3|refseq:NP_001001389.1|refseq:NP_001001390.1|refseq:NP_001001391.1|refseq:NP_001001392.1|refseq:NP_001189484.1|refseq:NP_001189485.1|refseq:NP_001189486.1|refseq:XP_011518790.1|dip:DIP-1121N|panther:PTHR10225(orthology-group)|ensembl:ENST00000263398.11|ensembl:ENSP00000263398.6|ensembl:ENST00000278386.10|ensembl:ENSP00000278386.6|ensembl:ENST00000352818.8|ensembl:ENSP00000309732.6|ensembl:ENST00000415148.6|ensembl:ENSP00000389830.2|ensembl:ENSP00000398632.2|ensembl:ENST00000433892.6|ensembl:ENSP00000392331.2|ensembl:ENST00000434472.6|ensembl:ENSP00000404447.2"	-	-	-	figure legend:SF5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:QOb28rF7/ryqfz/ylJFTyL3aoAc9606	intact-crc:2A5555CEC1FFC858|rigid:j9jiqOSEB2fUrqH+bCZFm1XTqTg	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9Y672	intact:EBI-10760263	intact:EBI-11337956|uniprotkb:B3KMU2|uniprotkb:Q9H3I0|uniprotkb:Q5SXR9|ensembl:ENSP00000263440.5	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	"psi-mi:alg6_human(display_long)|uniprotkb:ALG6(gene name)|psi-mi:ALG6(display_short)|uniprotkb:Asparagine-linked glycosylation protein 6 homolog(gene name synonym)|uniprotkb:""Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase""(gene name synonym)|uniprotkb:""Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase""(gene name synonym)|uniprotkb:My046(orf name)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036865|imex:IM-29092-144	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000088035.18(gene)|ensembl:ENST00000263440.6(transcript)|go:""GO:0004583""(dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0006488""(dolichol-linked oligosaccharide biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0042281""(dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity)|go:""GO:0046527""(glucosyltransferase activity)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR004856(ALG6, ALG8 glycosyltransferase)|mint:Q9Y672|reactome:R-HSA-446193|reactome:R-HSA-4724289|refseq:NP_037471.2|panther:PTHR12413(orthology-group)|efo:""Orphanet:79320"""	-	-	-	figure legend:SF5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:8dM/Kd12YNqCTrIOThU+GT0R+BE9606	intact-crc:2A5555CEC1FFC858|rigid:j9jiqOSEB2fUrqH+bCZFm1XTqTg	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P05023	intact:EBI-10760263	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|ensembl:ENSP00000295598.5|intact:EBI-10963133	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036865|imex:IM-29092-144	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR43294(orthology-group)|ensembl:ENSG00000163399.16(gene)|ensembl:ENST00000295598.10(transcript)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0005391""(""P-type sodium:potassium-exchanging transporter activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0007231""(osmosensory signaling pathway)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016791""(phosphatase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030315""(T-tubule)|go:""GO:0030424""(axon)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031090""(organelle membrane)|go:""GO:0031402""(sodium ion binding)|go:""GO:0031947""(negative regulation of glucocorticoid biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0045823""(positive regulation of heart contraction)|go:""GO:0045989""(positive regulation of striated muscle contraction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060342""(photoreceptor inner segment membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086009""(membrane repolarization)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903416""(response to glycoside)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990239""(steroid hormone binding)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|interpro:IPR050510|mint:P05023|rcsb pdb:7E1Z|rcsb pdb:7E20|rcsb pdb:7E21|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|efo:""Orphanet:521414""|efo:""Orphanet:564178"""	-	-	-	figure legend:SF5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:2A5555CEC1FFC858|rigid:j9jiqOSEB2fUrqH+bCZFm1XTqTg	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P20020	intact:EBI-10760263	intact:EBI-5279998|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|ensembl:ENSP00000392043.3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036865|imex:IM-29092-144	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000070961.17(gene)|efo:""Orphanet:528084""|ensembl:ENST00000428670.8(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0003056""(regulation of vascular associated smooth muscle contraction)|go:""GO:0005388""(P-type calcium transporter activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0015085""(calcium ion transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030501""(positive regulation of bone mineralization)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042995""(cell projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051481""(negative regulation of cytosolic calcium ion concentration)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098684""(photoreceptor ribbon synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1990034""(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P20020|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9662360|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_011536709.1|refseq:XP_016874847.1|panther:PTHR24093(orthology-group)"	-	-	-	figure legend:SF5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	intact-crc:2A5555CEC1FFC858|rigid:j9jiqOSEB2fUrqH+bCZFm1XTqTg	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:O15118	intact:EBI-10760263	intact:EBI-2368710|uniprotkb:Q9P130|ensembl:ENSP00000269228.4|uniprotkb:B4DET3	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:npc1_human(display_long)|uniprotkb:NPC1(gene name)|psi-mi:NPC1(display_short)|uniprotkb:Niemann-Pick C1 protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036865|imex:IM-29092-144	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"ensembl:ENSG00000141458.13(gene)|ensembl:ENST00000269228.10(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001889""(liver development)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007628""(adult walking behavior)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008206""(bile acid metabolic process)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010467""(gene expression)|go:""GO:0010878""(cholesterol storage)|go:""GO:0012501""(programmed cell death)|go:""GO:0015485""(cholesterol binding)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0022008""(neurogenesis)|go:""GO:0030299""(intestinal cholesterol absorption)|go:""GO:0030301""(cholesterol transport)|go:""GO:0031579""(membrane raft organization)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032365""(intracellular lipid transport)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0045121""(membrane raft)|go:""GO:0046686""(response to cadmium ion)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0120020""(cholesterol transfer activity)|go:""GO:1904036""(negative regulation of epithelial cell apoptotic process)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:2000900""(cyclodextrin metabolic process)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR004765(Niemann-Pick C type protein)|interpro:IPR032190|interpro:IPR053956|interpro:IPR053958|mint:O15118|rcsb pdb:3GKH|rcsb pdb:3GKI|rcsb pdb:3GKJ|rcsb pdb:3JD8|rcsb pdb:5F18|rcsb pdb:5F1B|rcsb pdb:5HNS|rcsb pdb:5JNX|rcsb pdb:5KWY|rcsb pdb:5U73|rcsb pdb:5U74|rcsb pdb:6UOX|rcsb pdb:6W5R|rcsb pdb:6W5S|rcsb pdb:6W5T|rcsb pdb:6W5U|rcsb pdb:6W5V|rcsb pdb:8EUS|reactome:R-HSA-8964038|refseq:NP_000262.2|dip:DIP-53217N|efo:""Orphanet:216972""|efo:""Orphanet:216975""|efo:""Orphanet:216978""|efo:""Orphanet:216981""|efo:""Orphanet:216986""|panther:PTHR45727(orthology-group)"	-	-	-	figure legend:SF5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:3kG4MGzeShC2D5FsPoZZm1lEGlk9606	intact-crc:2A5555CEC1FFC858|rigid:j9jiqOSEB2fUrqH+bCZFm1XTqTg	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P22059	intact:EBI-10760263	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036865|imex:IM-29092-144	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	-	-	-	figure legend:SF5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	intact-crc:2A5555CEC1FFC858|rigid:j9jiqOSEB2fUrqH+bCZFm1XTqTg	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61586	intact:EBI-10760263	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036865|imex:IM-29092-144	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	-	-	-	figure legend:SF5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:2A5555CEC1FFC858|rigid:j9jiqOSEB2fUrqH+bCZFm1XTqTg	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P62745	intact:EBI-10760263	intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|ensembl:ENSP00000272233.4|uniprotkb:B2R692	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036865|imex:IM-29092-144	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_004031.1|ensembl:ENSG00000143878.10(gene)|ensembl:ENST00000272233.6(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0001525""(angiogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0019003""(GDP binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032154""(cleavage furrow)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|panther:PTHR24072(orthology-group)"	-	-	-	figure legend:SF5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606	intact-crc:2A5555CEC1FFC858|rigid:j9jiqOSEB2fUrqH+bCZFm1XTqTg	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q8NEN9	intact:EBI-27033737	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642.5	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27039025|imex:IM-29092-150	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_776152.1|mint:Q8NEN9|rcsb pdb:7F6J|ensembl:ENSG00000165650.12(gene)|ensembl:ENST00000334464.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0046872""(metal ion binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|interpro:IPR046349|panther:PTHR21519(orthology-group)"	-	-	-	figure legend:SF6A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	intact-crc:A32975908F5D4A10|rigid:pG9dLoon82PRTdWmImss+UUcyOw	false	green fluorescent protein tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q8NEN9	intact:EBI-27033737	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642.5	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27038857|imex:IM-29092-148	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_776152.1|mint:Q8NEN9|rcsb pdb:7F6J|ensembl:ENSG00000165650.12(gene)|ensembl:ENST00000334464.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0046872""(metal ion binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|interpro:IPR046349|panther:PTHR21519(orthology-group)"	-	-	-	figure legend:F6C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	intact-crc:C1CF58CD87F471CA|rigid:pG9dLoon82PRTdWmImss+UUcyOw	false	green fluorescent protein tag:n-n|necessary binding region:270-291	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q8NEN9	intact:EBI-27033737	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642.5	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27054409|imex:IM-29092-162	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_776152.1|mint:Q8NEN9|rcsb pdb:7F6J|ensembl:ENSG00000165650.12(gene)|ensembl:ENST00000334464.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0046872""(metal ion binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|interpro:IPR046349|panther:PTHR21519(orthology-group)"	-	-	-	figure legend:F4B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	intact-crc:1F60FAE026A60997|rigid:pG9dLoon82PRTdWmImss+UUcyOw	false	ha tag:c-c	myc tag:c-c	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:D0ZIB5	uniprotkb:O95466	intact:EBI-27033646	intact:EBI-720020|uniprotkb:Q6DKG5|uniprotkb:Q6IBP3|uniprotkb:Q86UH1|uniprotkb:Q8N671|uniprotkb:Q8TDH1|uniprotkb:Q96H10|uniprotkb:D2DGW2|ensembl:ENSP00000329219.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:fmnl1_human(display_long)|uniprotkb:Leukocyte formin(gene name synonym)|uniprotkb:CLL-associated antigen KW-13(gene name synonym)|uniprotkb:FMNL1(gene name)|psi-mi:FMNL1(display_short)|uniprotkb:C17orf1(gene name synonym)|uniprotkb:C17orf1B(gene name synonym)|uniprotkb:FMNL(gene name synonym)|uniprotkb:FRL1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27035767|imex:IM-29092-97	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_005883.2|ensembl:ENSG00000184922.15(gene)|ensembl:ENST00000331495.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032059""(bleb)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR043592|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:O95466|rcsb pdb:4YDH|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:XP_006722126.1|refseq:XP_006722133.1|panther:PTHR45857(orthology-group)"	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:SN1xgeqb5yPUjiaEv2H/kyDrD4c9606	intact-crc:3A9E37031367411F|rigid:3TmiB+FGHZ3f0mzmXhBBDbnTcCg	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q8NEN9	intact:EBI-27033737	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642.5	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27038813|imex:IM-29092-146	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_776152.1|mint:Q8NEN9|rcsb pdb:7F6J|ensembl:ENSG00000165650.12(gene)|ensembl:ENST00000334464.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0046872""(metal ion binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|interpro:IPR046349|panther:PTHR21519(orthology-group)"	-	-	-	"figure legend:F6B|comment:""\""Deleting the C-terminal 20 amino acids of PipB (Δ272–291) disrupted PipB-PDZD8 binding but alone was not sufficient for the interaction with PDZD8, as deletion of the N-terminal 188 amino acids (Δ1–188) also disrupted PDZD8 binding (Figure 6A).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2021/07/12	2024/11/14	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	intact-crc:5EEE56F3B8B16151|rigid:pG9dLoon82PRTdWmImss+UUcyOw	false	-	necessary binding region:930-1154	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q8NEN9	intact:EBI-27033737	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642.5	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27053884|imex:IM-29092-159	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_776152.1|mint:Q8NEN9|rcsb pdb:7F6J|ensembl:ENSG00000165650.12(gene)|ensembl:ENST00000334464.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0046872""(metal ion binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|interpro:IPR046349|panther:PTHR21519(orthology-group)"	-	-	-	"figure legend:F6a|comment:""\""Deleting the C-terminal 20 amino acids of PipB (Δ272–291) disrupted PipB-PDZD8 binding but alone was not sufficient for the interaction with PDZD8, as deletion of the N-terminal 188 amino acids (Δ1–188) also disrupted PDZD8 binding (Figure 6A).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2021/07/12	2024/11/14	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	intact-crc:E8D630A095CD9662|rigid:pG9dLoon82PRTdWmImss+UUcyOw	false	necessary binding region:1-188|necessary binding region:273-281|sufficient binding region:1-281	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q8NEN9	intact:EBI-27033737	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642.5	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27039048|imex:IM-29092-152	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_776152.1|mint:Q8NEN9|rcsb pdb:7F6J|ensembl:ENSG00000165650.12(gene)|ensembl:ENST00000334464.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0046872""(metal ion binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|interpro:IPR046349|panther:PTHR21519(orthology-group)"	-	-	-	figure legend:F6D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	intact-crc:1D18D494FE1FB96F|rigid:pG9dLoon82PRTdWmImss+UUcyOw	false	green fluorescent protein tag:n-n	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q8NEN9	intact:EBI-27033737	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642.5	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27039057|imex:IM-29092-154	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_776152.1|mint:Q8NEN9|rcsb pdb:7F6J|ensembl:ENSG00000165650.12(gene)|ensembl:ENST00000334464.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0046872""(metal ion binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|interpro:IPR046349|panther:PTHR21519(orthology-group)"	-	-	-	figure legend:F6F|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	intact-crc:076932A179A5F281|rigid:pG9dLoon82PRTdWmImss+UUcyOw	false	ha tag:c-c	myc tag:c-c	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:D0ZIB5	uniprotkb:O95466	intact:EBI-27033646	intact:EBI-720020|uniprotkb:Q6DKG5|uniprotkb:Q6IBP3|uniprotkb:Q86UH1|uniprotkb:Q8N671|uniprotkb:Q8TDH1|uniprotkb:Q96H10|uniprotkb:D2DGW2|ensembl:ENSP00000329219.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:fmnl1_human(display_long)|uniprotkb:Leukocyte formin(gene name synonym)|uniprotkb:CLL-associated antigen KW-13(gene name synonym)|uniprotkb:FMNL1(gene name)|psi-mi:FMNL1(display_short)|uniprotkb:C17orf1(gene name synonym)|uniprotkb:C17orf1B(gene name synonym)|uniprotkb:FMNL(gene name synonym)|uniprotkb:FRL1(gene name synonym)	"psi-mi:""MI:0071""(molecular sieving)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27039083|imex:IM-29092-156	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_005883.2|ensembl:ENSG00000184922.15(gene)|ensembl:ENST00000331495.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032059""(bleb)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR043592|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:O95466|rcsb pdb:4YDH|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:XP_006722126.1|refseq:XP_006722133.1|panther:PTHR45857(orthology-group)"	-	-	-	figure legend:F7A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/12	2024/11/14	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:SN1xgeqb5yPUjiaEv2H/kyDrD4c9606	intact-crc:E840784C7650B45A|rigid:3TmiB+FGHZ3f0mzmXhBBDbnTcCg	false	mutation with no effect:256-256|his tag:?-?	glutathione s tranferase tag:n-n|sufficient binding region:1-385	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:D0ZIB5	uniprotkb:O95466	intact:EBI-27033646	intact:EBI-720020|uniprotkb:Q6DKG5|uniprotkb:Q6IBP3|uniprotkb:Q86UH1|uniprotkb:Q8N671|uniprotkb:Q8TDH1|uniprotkb:Q96H10|uniprotkb:D2DGW2|ensembl:ENSP00000329219.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:fmnl1_human(display_long)|uniprotkb:Leukocyte formin(gene name synonym)|uniprotkb:CLL-associated antigen KW-13(gene name synonym)|uniprotkb:FMNL1(gene name)|psi-mi:FMNL1(display_short)|uniprotkb:C17orf1(gene name synonym)|uniprotkb:C17orf1B(gene name synonym)|uniprotkb:FMNL(gene name synonym)|uniprotkb:FRL1(gene name synonym)	"psi-mi:""MI:0424""(protein kinase assay)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27039129|imex:IM-29092-158	intact-miscore:0.68	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_005883.2|ensembl:ENSG00000184922.15(gene)|ensembl:ENST00000331495.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032059""(bleb)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR043592|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:O95466|rcsb pdb:4YDH|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:XP_006722126.1|refseq:XP_006722133.1|panther:PTHR45857(orthology-group)"	"go:""GO:0004672""(protein kinase activity)|go:""GO:0006468""(protein phosphorylation)"	-	-	figure legend:F7B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/12	2024/11/14	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:SN1xgeqb5yPUjiaEv2H/kyDrD4c9606	intact-crc:603B782BB7AC1369|rigid:3TmiB+FGHZ3f0mzmXhBBDbnTcCg	false	mutation disrupting interaction:256-256|his tag:?-?	glutathione s tranferase tag:n-n|sufficient binding region:1-385	-	-	"psi-mi:""MI:0821""(molecular weight estimation by autoradiography)"	"psi-mi:""MI:0821""(molecular weight estimation by autoradiography)"
uniprotkb:D0ZIB5	uniprotkb:O95466	intact:EBI-27033646	intact:EBI-720020|uniprotkb:Q6DKG5|uniprotkb:Q6IBP3|uniprotkb:Q86UH1|uniprotkb:Q8N671|uniprotkb:Q8TDH1|uniprotkb:Q96H10|uniprotkb:D2DGW2|ensembl:ENSP00000329219.2	psi-mi:stec_salt1(display_long)|uniprotkb:steC(gene name)|psi-mi:steC(display_short)|uniprotkb:Salmonella translocated effector C(gene name synonym)|uniprotkb:STM14_2050(locus name)	psi-mi:fmnl1_human(display_long)|uniprotkb:Leukocyte formin(gene name synonym)|uniprotkb:CLL-associated antigen KW-13(gene name synonym)|uniprotkb:FMNL1(gene name)|psi-mi:FMNL1(display_short)|uniprotkb:C17orf1(gene name synonym)|uniprotkb:C17orf1B(gene name synonym)|uniprotkb:FMNL(gene name synonym)|uniprotkb:FRL1(gene name synonym)	"psi-mi:""MI:0019""(coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27035775|imex:IM-29092-115	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016301""(kinase activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:8JBI|mint:D0ZIB5|refseq:WP_001116926.1"	"refseq:NP_005883.2|ensembl:ENSG00000184922.15(gene)|ensembl:ENST00000331495.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032059""(bleb)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR043592|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:O95466|rcsb pdb:4YDH|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:XP_006722126.1|refseq:XP_006722133.1|panther:PTHR45857(orthology-group)"	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:LTCZ0GJcooxTql4Ae6zYn4jouoY588858	rogid:SN1xgeqb5yPUjiaEv2H/kyDrD4c9606	intact-crc:76C799EB257BD252|rigid:3TmiB+FGHZ3f0mzmXhBBDbnTcCg	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0F6B5H5	uniprotkb:P04083	intact:EBI-27033185	intact:EBI-354007|ensembl:ENSP00000257497.6|ensembl:ENSP00000366109.1|uniprotkb:B5BU38	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	"psi-mi:""MI:0019""(coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036147|imex:IM-29092-13	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_000691.1|ensembl:ENSG00000135046.15(gene)|ensembl:ENST00000257497.11(transcript)|ensembl:ENST00000376911.2(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002685""(regulation of leukocyte migration)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007187""(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:""GO:0008289""(lipid binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014839""(myoblast migration involved in skeletal muscle regeneration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031514""(motile cilium)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032652""(regulation of interleukin-1 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0033031""(positive regulation of neutrophil apoptotic process)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045627""(positive regulation of T-helper 1 cell differentiation)|go:""GO:0045629""(negative regulation of T-helper 2 cell differentiation)|go:""GO:0045920""(negative regulation of exocytosis)|go:""GO:0046632""(alpha-beta T cell differentiation)|mint:P04083|go:""GO:0046883""(regulation of hormone secretion)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050482""(arachidonate secretion)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071621""(granulocyte chemotaxis)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|refseq:XP_011516911.1|dip:DIP-32875N|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/28	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	intact-crc:309860BDA8C0850E|rigid:4JVfB8gEYZE1BfXnIsStAh+oPNs	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0F6AZQ1	uniprotkb:Q8NEN9	intact:EBI-27033737	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642.5	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	"psi-mi:""MI:0019""(coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036153|imex:IM-29092-31	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_776152.1|mint:Q8NEN9|rcsb pdb:7F6J|ensembl:ENSG00000165650.12(gene)|ensembl:ENST00000334464.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0046872""(metal ion binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|interpro:IPR046349|panther:PTHR21519(orthology-group)"	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	intact-crc:FA5557F933334957|rigid:pG9dLoon82PRTdWmImss+UUcyOw	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0F6AZQ1	uniprotkb:P04083	intact:EBI-27033737	intact:EBI-354007|ensembl:ENSP00000257497.6|ensembl:ENSP00000366109.1|uniprotkb:B5BU38	psi-mi:a0a0f6azq1_salt1(display_long)|uniprotkb:pipB(gene name)|psi-mi:pipB(display_short)|uniprotkb:STM14_1233(locus name)	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	"psi-mi:""MI:0019""(coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036159|imex:IM-29092-117	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6AZQ1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|interpro:IPR051082|refseq:WP_001123045.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_000691.1|ensembl:ENSG00000135046.15(gene)|ensembl:ENST00000257497.11(transcript)|ensembl:ENST00000376911.2(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002685""(regulation of leukocyte migration)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007187""(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:""GO:0008289""(lipid binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014839""(myoblast migration involved in skeletal muscle regeneration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031514""(motile cilium)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032652""(regulation of interleukin-1 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0033031""(positive regulation of neutrophil apoptotic process)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045627""(positive regulation of T-helper 1 cell differentiation)|go:""GO:0045629""(negative regulation of T-helper 2 cell differentiation)|go:""GO:0045920""(negative regulation of exocytosis)|go:""GO:0046632""(alpha-beta T cell differentiation)|mint:P04083|go:""GO:0046883""(regulation of hormone secretion)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050482""(arachidonate secretion)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071621""(granulocyte chemotaxis)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|refseq:XP_011516911.1|dip:DIP-32875N|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/28	rogid:6vWnSD0BMnF0eViRr3HaQbMhbFg588858	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	intact-crc:078654A3FC64E869|rigid:cJfAyIRFt7PNkWRfrup2ZdMO068	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P04083	intact:EBI-10760263	intact:EBI-354007|ensembl:ENSP00000257497.6|ensembl:ENSP00000366109.1|uniprotkb:B5BU38	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	"psi-mi:""MI:0019""(coimmunoprecipitation)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27036165|imex:IM-29092-33	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_000691.1|ensembl:ENSG00000135046.15(gene)|ensembl:ENST00000257497.11(transcript)|ensembl:ENST00000376911.2(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002685""(regulation of leukocyte migration)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007187""(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:""GO:0008289""(lipid binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014839""(myoblast migration involved in skeletal muscle regeneration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031514""(motile cilium)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032652""(regulation of interleukin-1 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0033031""(positive regulation of neutrophil apoptotic process)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045627""(positive regulation of T-helper 1 cell differentiation)|go:""GO:0045629""(negative regulation of T-helper 2 cell differentiation)|go:""GO:0045920""(negative regulation of exocytosis)|go:""GO:0046632""(alpha-beta T cell differentiation)|mint:P04083|go:""GO:0046883""(regulation of hormone secretion)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050482""(arachidonate secretion)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071621""(granulocyte chemotaxis)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|refseq:XP_011516911.1|dip:DIP-32875N|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/02/28	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	intact-crc:D229D5A07055670F|rigid:vIbmRWqPpmmP+4ttpWqHihBJA3M	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q29ST3	uniprotkb:Q9H0U4	intact:EBI-15838677	intact:EBI-1045214|uniprotkb:A8K7S1|ensembl:ENSP00000310226.6	psi-mi:drra_legpn(display_long)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:sidM(gene name synonym)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)	psi-mi:rab1b_human(display_long)|uniprotkb:RAB1B(gene name)|psi-mi:RAB1B(display_short)	"psi-mi:""MI:0949""(gdp/gtp exchange assay)"	Vieweg et al. (2020)	pubmed:32227113|imex:IM-28067	taxid:446(legpn)|taxid:446(Legionella pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-25611201|imex:IM-28067-35	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0018117""(protein adenylylation)|go:""GO:0018260""(protein guanylylation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044162""(host cell cytoplasmic vesicle membrane)|go:""GO:0044600""(protein guanylyltransferase activity)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070733""(AMPylase activity)|interpro:IPR028057|interpro:IPR033784|interpro:IPR038346|interpro:IPR048717|interpro:IPR048718|rcsb pdb:3NKU|rcsb pdb:5O74|rcsb pdb:6YX5|refseq:WP_010948166.1|dip:DIP-58604N|mint:Q29ST3"	"refseq:NP_112243.1|dip:DIP-42462N|ensembl:ENSG00000174903.16(gene)|ensembl:ENST00000311481.11(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0019068""(virion assembly)|go:""GO:0030133""(transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:Q9H0U4|rcsb pdb:3JZA|rcsb pdb:3NKV|rcsb pdb:4HLQ|rcsb pdb:4I1O|rcsb pdb:5O74|rcsb pdb:5SZH|rcsb pdb:5SZK|rcsb pdb:6SKU|rcsb pdb:8ALK|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	"go:""GO:0017112"""	-	-	figure legend:Supp. figure 6A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|curation depth:imex curation|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/04/07	2025/03/10	rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE446	rogid:EI6DHq7xCboSkoqGY5NmVY4Iqf09606	intact-crc:E29AA23E8E5F8369	false	-	sufficient binding region:3-174(IPR001806)|his tag:c-c|O-phospho-L-serine:111-111	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8X482	uniprotkb:Q5T0N5-3	intact:EBI-22229752	intact:EBI-4403262|ensembl:ENSP00000359275.2	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	psi-mi:q5t0n5-3(display_long)|uniprotkb:FNBP1L(gene name)|psi-mi:FNBP1L(display_short)|uniprotkb:C1orf39(gene name synonym)|uniprotkb:TOCA1(gene name synonym)|uniprotkb:Transducer of Cdc42-dependent actin assembly protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Campellone et al. (2012)	pubmed:22544751|imex:IM-27780	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25468502|imex:IM-27780-1	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	intact:EBI-714058(isoform-parent)|ensembl:ENSG00000137942.18(gene)|ensembl:ENST00000370253.6(transcript)	-	-	-	figure legend:fig. 6a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/03/05	2024/11/14	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	rogid:MpFSdw9824VChZs3SiA7/yrwyGE9606	intact-crc:9426BB5C5FDAD169|rigid:9SAwwS98Obr5N2at6F/NN4xoKP8	false	his tag:n-n|myc tag:c-c|binding-associated region:134-384	green fluorescent protein tag:?-?|mutation disrupting interaction:518-518	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q8X482	uniprotkb:Q5T0N5-3	intact:EBI-22229752	intact:EBI-4403262|ensembl:ENSP00000359275.2	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	psi-mi:q5t0n5-3(display_long)|uniprotkb:FNBP1L(gene name)|psi-mi:FNBP1L(display_short)|uniprotkb:C1orf39(gene name synonym)|uniprotkb:TOCA1(gene name synonym)|uniprotkb:Transducer of Cdc42-dependent actin assembly protein 1(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Campellone et al. (2012)	pubmed:22544751|imex:IM-27780	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25468524|imex:IM-27780-3	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	intact:EBI-714058(isoform-parent)|ensembl:ENSG00000137942.18(gene)|ensembl:ENST00000370253.6(transcript)	-	-	-	figure legend:fig. 6b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/03/05	2024/11/14	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	rogid:MpFSdw9824VChZs3SiA7/yrwyGE9606	intact-crc:BDDDD80D29BD76E9|rigid:9SAwwS98Obr5N2at6F/NN4xoKP8	false	myc tag:c-c|binding-associated region:134-384|his tag:n-n	his tag:?-?|mutation disrupting interaction:518-518	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q8X482	uniprotkb:Q5T0N5-3	intact:EBI-22229752	intact:EBI-4403262|ensembl:ENSP00000359275.2	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	psi-mi:q5t0n5-3(display_long)|uniprotkb:FNBP1L(gene name)|psi-mi:FNBP1L(display_short)|uniprotkb:C1orf39(gene name synonym)|uniprotkb:TOCA1(gene name synonym)|uniprotkb:Transducer of Cdc42-dependent actin assembly protein 1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Campellone et al. (2012)	pubmed:22544751|imex:IM-27780	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25468561|imex:IM-27780-5	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	intact:EBI-714058(isoform-parent)|ensembl:ENSG00000137942.18(gene)|ensembl:ENST00000370253.6(transcript)	-	-	-	figure legend:fig. 6d|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/03/05	2024/11/14	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	rogid:MpFSdw9824VChZs3SiA7/yrwyGE9606	intact-crc:D2C42110F7666821|rigid:9SAwwS98Obr5N2at6F/NN4xoKP8	false	binding-associated region:80-384	mutation disrupting interaction:518-518|sufficient binding region:481-546	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8X482	uniprotkb:Q9UHR4	intact:EBI-22229752	intact:EBI-2483278|uniprotkb:A4D268|uniprotkb:Q75L21|uniprotkb:Q75L22|uniprotkb:Q96CV4|uniprotkb:Q9H5F5|uniprotkb:Q9Y2M8|ensembl:ENSP00000005260.8	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	psi-mi:bi2l1_human(display_long)|uniprotkb:BAIAP2L1(gene name)|psi-mi:BAIAP2L1(display_short)|uniprotkb:IRTKS(gene name synonym)|uniprotkb:Insulin receptor tyrosine kinase substrate(gene name synonym)|uniprotkb:Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Campellone et al. (2012)	pubmed:22544751|imex:IM-27780	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25468605|imex:IM-27780-7	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	"refseq:NP_061330.2|dip:DIP-53820N|ensembl:ENSG00000006453.14(gene)|ensembl:ENST00000005260.9(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030060|interpro:IPR035592|interpro:IPR036028|mint:Q9UHR4|rcsb pdb:2KXC|rcsb pdb:2LNH|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR14206(orthology-group)"	-	-	-	figure legend:fig. 6f|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/03/05	2025/01/27	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	rogid:ig7xSOv8h6Y4vYE0/n228+ZLWaM9606	intact-crc:447CFCED70C40DEB|rigid:87I9/x/MwMaqS3jWyTZzdBlLmi0	false	biotin tag:?-?|binding-associated region:340-355	glutathione s tranferase tag:?-?|binding-associated region:337-403	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:Q8X482	uniprotkb:Q9UQB8	intact:EBI-22229752	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338.6	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Brain-specific angiogenesis inhibitor 1-associated protein 2(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Campellone et al. (2012)	pubmed:22544751|imex:IM-27780	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25468623|imex:IM-27780-9	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	"ensembl:ENSG00000175866.16(gene)|ensembl:ENST00000321300.10(transcript)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001726""(ruffle)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0007409""(axonogenesis)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016358""(dendrite development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030141""(secretory granule)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030175""(filopodium)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043198""(dendritic shaft)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060076""(excitatory synapse)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0061845""(neuron projection branch point)|go:""GO:0061846""(dendritic spine cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:2000463""(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|panther:PTHR14206(orthology-group)"	-	-	-	figure legend:fig. 6f|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/03/05	2024/12/31	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	intact-crc:0F426FB611DC08DE|rigid:uDBnOUHggDC9kS8o0Std5DXj2lM	false	biotin tag:?-?|binding-associated region:340-355	glutathione s tranferase tag:?-?|binding-associated region:337-403	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:Q8X509	uniprotkb:P62837	intact:EBI-25438289|uniprotkb:A0A0H3JH14|uniprotkb:Q7ADX4|uniprotkb:A0A6M0JRY3	intact:EBI-347677|ensembl:ENSP00000381717.3|ensembl:ENSP00000381718.4|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6	psi-mi:q8x509_eco57(display_long)|uniprotkb:nleG2-3(gene name)|psi-mi:nleG2-3(display_short)|uniprotkb:ECs_2156(orf name)	"psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 2""(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D2""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)"	"psi-mi:""MI:0077""(nuclear magnetic resonance)"	Wu et al. (2010)	pubmed:20585566|imex:IM-27765	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25438287|imex:IM-27765-1	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)|rcsb pdb:2KKX|rcsb pdb:2KKY|refseq:WP_001131658.1|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|refseq:NP_310183.1|mint:Q8X509"	"ensembl:ENSG00000131508.17(gene)|ensembl:ENST00000398733.8(transcript)|ensembl:ENST00000398734.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036211""(protein modification process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|rcsb pdb:7R71|rcsb pdb:8B3I|rcsb pdb:8GBQ|rcsb pdb:8GCB|rcsb pdb:8GRM|rcsb pdb:8JWJ|rcsb pdb:8JWU|rcsb pdb:8VK8|rcsb pdb:8VK9|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:fig. 6a-b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/02/24	2025/01/19	rogid:tSug3VBBQ0q88LIn9xPI2Q/K9iA83334	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:D37B7A3BD5AA9CF1|rigid:UBZMZc79ATq3EK/vweoxpxitdqs	false	binding-associated region:90-191	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P62837	uniprotkb:Q8X4X3	intact:EBI-347677|ensembl:ENSP00000381717.3|ensembl:ENSP00000381718.4|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6	intact:EBI-25438357|uniprotkb:A0A0H3JEU0|uniprotkb:Q7AE95	"psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 2""(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D2""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)"	psi-mi:q8x4x3_eco57(display_long)|uniprotkb:nleG5-1(gene name)|psi-mi:nleG5-1(display_short)|uniprotkb:ECs_1996(orf name)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Wu et al. (2010)	pubmed:20585566|imex:IM-27765	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25438319|imex:IM-27765-3	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000131508.17(gene)|ensembl:ENST00000398733.8(transcript)|ensembl:ENST00000398734.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036211""(protein modification process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|rcsb pdb:7R71|rcsb pdb:8B3I|rcsb pdb:8GBQ|rcsb pdb:8GCB|rcsb pdb:8GRM|rcsb pdb:8JWJ|rcsb pdb:8JWU|rcsb pdb:8VK8|rcsb pdb:8VK9|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|panther:PTHR24068(orthology-group)"	"go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0044403""(biological process involved in symbiotic interaction)|rcsb pdb:6B3N|interpro:IPR010489(Protein of unknown function DUF1076)|interpro:IPR038436|refseq:NP_310023.1|refseq:WP_001143784.1|mint:Q8X4X3"	-	-	-	"figure legend:fig. 7c|comment:""\""To quantify the NleG5-1[1–213] interactions with UBE2D2 variants, we labelled the three UBE2D2 mutant proteins described above with fluorescein-5-maleimide and monitored the change in fluorescence polarization upon titration of NleG5-1[1–213] (Figure 7C). Kd values for NleG5-1[1–213] interactions with UBE2D2 R5A, F62A and K63A mutants were 326±35, 36±2 and 213±9 µM, respectively. Compared to the Kd for NleG5-1[1–213] interaction with wild type UBE2D2, presented above (56±2 µM) the affinity of R5A and K63A mutants were approximately 5 and 3 times lower, respectively, while the affinity of the F62A mutant was slightly higher.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:56.0x10^-6 ~2.0(molar)	2020/02/24	2025/01/19	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rogid:hY+PmA0nI/a+CZ3MdCp0eYm/5DM83334	intact-crc:701686DF39DB4D0D|rigid:pxeRUJB6nVRGIOCkUeAJh1O/FlU	false	mutation increasing interaction rate:62-62|fluorescein-5-maleimide label:?-?|mutation decreasing interaction rate:5-5|mutation decreasing interaction rate:63-63	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:O14745	uniprotkb:B7UMA0	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613.5|uniprotkb:B3KY21|intact:EBI-15579389	intact:EBI-2529418	"psi-mi:nhrf1_human(display_long)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)|uniprotkb:NHERF1(gene name)|psi-mi:NHERF1(display_short)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:NHERF(gene name synonym)|uniprotkb:""Regulatory cofactor of Na(+)/H(+) exchanger""(gene name synonym)|uniprotkb:SLC9A3R1(gene name synonym)"	psi-mi:b7uma0_eco27(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:E2348C_3942(locus name)	"psi-mi:""MI:0089""(protein array)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25435467|imex:IM-27748-1	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109062.12(gene)|ensembl:ENST00000262613.10(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0003096""(renal sodium ion transport)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005902""(microvillus)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0007191""(adenylate cyclase-activating dopamine receptor signaling pathway)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0010642""(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:""GO:0010761""(fibroblast migration)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0010766""(negative regulation of sodium ion transport)|go:""GO:0012505""(endomembrane system)|go:""GO:0015185""(gamma-aminobutyric acid transmembrane transporter activity)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0017081""(chloride channel regulator activity)|go:""GO:0019902""(phosphatase binding)|go:""GO:0022612""(gland morphogenesis)|go:""GO:0030033""(microvillus assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030175""(filopodium)|go:""GO:0030643""(intracellular phosphate ion homeostasis)|go:""GO:0031526""(brush border membrane)|go:""GO:0031528""(microvillus membrane)|go:""GO:0031698""(beta-2 adrenergic receptor binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0031982""(vesicle)|go:""GO:0032426""(stereocilium tip)|go:""GO:0032782""(bile acid secretion)|go:""GO:0034635""(glutathione transport)|go:""GO:0034767""(positive regulation of monoatomic ion transmembrane transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044782""(cilium organization)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045159""(myosin II binding)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045199""(maintenance of epithelial cell apical/basal polarity)|go:""GO:0045859""(regulation of protein kinase activity)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050780""(dopamine receptor binding)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051939""(gamma-aminobutyric acid import)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060158""(phospholipase C-activating dopamine receptor signaling pathway)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070293""(renal absorption)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070851""(growth factor receptor binding)|go:""GO:0071944""(cell periphery)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0090660""(cerebrospinal fluid circulation)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097291""(renal phosphate ion absorption)|go:""GO:0098739""(import across plasma membrane)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:0099103""(channel activator activity)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1903402""(regulation of renal phosphate excretion)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4MPA|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|refseq:NP_004243.1|dip:DIP-29092N|panther:PTHR14191(orthology-group)|efo:""Orphanet:244305"""	interpro:IPR004959(IpaB/EvcA)|refseq:WP_000492694.1|mint:B7UMA0	-	-	-	figure legend:fig. 1a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/02/24	2024/11/14	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	rogid:K4h+E0YhHOWoenZOShinG380h9E574521	intact-crc:FF44B3526F75081C|rigid:9N6zfMUaHftDDUGlHCEeS84Mbig	false	sufficient binding region:14-94|sufficient binding region:154-234	glutathione s tranferase tag:?-?|binding-associated region:154-203	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q15599	uniprotkb:B7UMA0	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-2529418	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:b7uma0_eco27(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:E2348C_3942(locus name)	"psi-mi:""MI:0089""(protein array)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25435535|imex:IM-27748-3	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	interpro:IPR004959(IpaB/EvcA)|refseq:WP_000492694.1|mint:B7UMA0	-	-	-	figure legend:fig. 1a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:K4h+E0YhHOWoenZOShinG380h9E574521	intact-crc:8F7152BC2B99E5CD|rigid:9S3jRUFg3rxHblysBY9bbse5hf8	false	sufficient binding region:11-90|sufficient binding region:150-230	glutathione s tranferase tag:?-?|binding-associated region:154-203	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q15599	uniprotkb:Q8X831	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-16088619|uniprotkb:A0A0H3JEC3|uniprotkb:Q7AGE1	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:q8x831_eco57(display_long)|uniprotkb:nleH1-1(gene name)|psi-mi:nleH1-1(display_short)|uniprotkb:ECs_0848(orf name)	"psi-mi:""MI:0089""(protein array)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25435547|imex:IM-27748-5	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	"refseq:NP_308875.1|refseq:WP_000951026.1|dip:DIP-60658N|go:""GO:0042326""(negative regulation of phosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0140403""(effector-mediated suppression of host innate immune response)|go:""GO:0140416""(transcription regulator inhibitor activity)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4LRJ|mint:Q8X831"	-	-	-	figure legend:fig. 1a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:nxwz4f65gXQxF5wdPpZ+bR7YEkw83334	intact-crc:A2E8B32F6C43BD38|rigid:UmffcJjm+itHsg7q5yNS963nxVc	false	sufficient binding region:150-230	glutathione s tranferase tag:?-?|binding-associated region:144-293	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q15599	uniprotkb:B7UMA0	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-2529418	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:b7uma0_eco27(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:E2348C_3942(locus name)	"psi-mi:""MI:0047""(far western blotting)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25435580|imex:IM-27748-7	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	interpro:IPR004959(IpaB/EvcA)|refseq:WP_000492694.1|mint:B7UMA0	-	-	-	figure legend:fig. 1b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:K4h+E0YhHOWoenZOShinG380h9E574521	intact-crc:E8322D4A7184B109|rigid:9S3jRUFg3rxHblysBY9bbse5hf8	false	his tag:?-?	maltose binding protein tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q15599	uniprotkb:B7UMA0	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-2529418	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:b7uma0_eco27(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:E2348C_3942(locus name)	"psi-mi:""MI:0047""(far western blotting)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25435593|imex:IM-27748-9	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	interpro:IPR004959(IpaB/EvcA)|refseq:WP_000492694.1|mint:B7UMA0	-	-	-	figure legend:fig. 1b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:K4h+E0YhHOWoenZOShinG380h9E574521	intact-crc:26E50A0991A97ED5|rigid:9S3jRUFg3rxHblysBY9bbse5hf8	false	maltose binding protein tag:?-?|sufficient binding region:150-230	maltose binding protein tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q15599	uniprotkb:B7UR60	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-25435618	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	"psi-mi:""MI:0047""(far western blotting)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25435623|imex:IM-27748-11	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	mint:B7UR60|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	intact-crc:623BD8F67AA9F5B0|rigid:uta98I2Rt9s9h2ckdisEtP3ay4M	false	his tag:?-?	maltose binding protein tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q15599	uniprotkb:B7UR60	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-25435618	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	"psi-mi:""MI:0047""(far western blotting)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25435631|imex:IM-27748-13	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	mint:B7UR60|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	intact-crc:4A6D6385552FF1C4|rigid:uta98I2Rt9s9h2ckdisEtP3ay4M	false	maltose binding protein tag:?-?|sufficient binding region:150-230	maltose binding protein tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q15599	uniprotkb:Q8X831	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-16088619|uniprotkb:A0A0H3JEC3|uniprotkb:Q7AGE1	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:q8x831_eco57(display_long)|uniprotkb:nleH1-1(gene name)|psi-mi:nleH1-1(display_short)|uniprotkb:ECs_0848(orf name)	"psi-mi:""MI:0047""(far western blotting)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25435641|imex:IM-27748-15	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	"refseq:NP_308875.1|refseq:WP_000951026.1|dip:DIP-60658N|go:""GO:0042326""(negative regulation of phosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0140403""(effector-mediated suppression of host innate immune response)|go:""GO:0140416""(transcription regulator inhibitor activity)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4LRJ|mint:Q8X831"	-	-	-	figure legend:fig. 1b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:nxwz4f65gXQxF5wdPpZ+bR7YEkw83334	intact-crc:D7C2D6B5353F8CCE|rigid:UmffcJjm+itHsg7q5yNS963nxVc	false	his tag:?-?	maltose binding protein tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B7UR60	uniprotkb:Q15599	intact:EBI-25435618	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25436595|imex:IM-27748-16	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	-	-	-	figure legend:fig. 1e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2020/02/24	2024/11/14	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	intact-crc:2761CE275AC91D13|rigid:uta98I2Rt9s9h2ckdisEtP3ay4M	false	his tag:?-?	his tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q8X831	uniprotkb:Q15599	intact:EBI-16088619|uniprotkb:A0A0H3JEC3|uniprotkb:Q7AGE1	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	psi-mi:q8x831_eco57(display_long)|uniprotkb:nleH1-1(gene name)|psi-mi:nleH1-1(display_short)|uniprotkb:ECs_0848(orf name)	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25436603|imex:IM-27748-18	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_308875.1|refseq:WP_000951026.1|dip:DIP-60658N|go:""GO:0042326""(negative regulation of phosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0140403""(effector-mediated suppression of host innate immune response)|go:""GO:0140416""(transcription regulator inhibitor activity)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4LRJ|mint:Q8X831"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	-	-	-	figure legend:fig. 1e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2020/02/24	2024/11/14	rogid:nxwz4f65gXQxF5wdPpZ+bR7YEkw83334	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	intact-crc:E0B338728E8BF206|rigid:UmffcJjm+itHsg7q5yNS963nxVc	false	glutathione s tranferase tag:?-?	his tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q15599	uniprotkb:B7UR60	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-25435618	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25436623|imex:IM-27748-20	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	mint:B7UR60|refseq:WP_001025663.1	-	-	-	"figure legend:fig.2a|comment:""\""Probing infected cell extracts with anti-EspI and anti NleH1 revealed that while both full-length EspI and EspIΔC7 were found in equal amounts, NleH1ΔC4 was unstable (Fig. 2A and B). Following cell lysis the supernatants were subjected to co-immunoprecipitation with anti-HA antibodies. While NHERF2 did not co-immunoprecipitate EspIΔC7 (Fig. 2A) and NleH1ΔC4 (Fig. 2B), both full-length EspI (Fig. 2A) and NleH1 (Fig. 2B) were co-immunoprecipitated.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	intact-crc:B2FD72278E18A708|rigid:uta98I2Rt9s9h2ckdisEtP3ay4M	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q15599	uniprotkb:Q8X831	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-16088619|uniprotkb:A0A0H3JEC3|uniprotkb:Q7AGE1	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:q8x831_eco57(display_long)|uniprotkb:nleH1-1(gene name)|psi-mi:nleH1-1(display_short)|uniprotkb:ECs_0848(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25436630|imex:IM-27748-22	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	"refseq:NP_308875.1|refseq:WP_000951026.1|dip:DIP-60658N|go:""GO:0042326""(negative regulation of phosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0140403""(effector-mediated suppression of host innate immune response)|go:""GO:0140416""(transcription regulator inhibitor activity)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4LRJ|mint:Q8X831"	-	-	-	"figure legend:fig.2b|comment:""\""Probing infected cell extracts with anti-EspI and anti NleH1 revealed that while both full-length EspI and EspIΔC7 were found in equal amounts, NleH1ΔC4 was unstable (Fig. 2A and B). Following cell lysis the supernatants were subjected to co-immunoprecipitation with anti-HA antibodies. While NHERF2 did not co-immunoprecipitate EspIΔC7 (Fig. 2A) and NleH1ΔC4 (Fig. 2B), both full-length EspI (Fig. 2A) and NleH1 (Fig. 2B) were co-immunoprecipitated.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:nxwz4f65gXQxF5wdPpZ+bR7YEkw83334	intact-crc:C7B7EE10EE050FCC|rigid:UmffcJjm+itHsg7q5yNS963nxVc	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q15599	uniprotkb:B7UR60	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-25435618	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25436646|imex:IM-27748-24	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	mint:B7UR60|refseq:WP_001025663.1	"go:""GO:0005886""(plasma membrane)"	-	-	"figure legend:fig. 3 suppl fig.2|comment:""\""In order to determine if the effectors colocalize with NHERF2, HeLa–NHERF2 cells were transfected with pRK5 (Fig. 3) or pRK5 expressing myc-tagged Map, MapΔC3, NleH1 and NleH1ΔC4 as well as pGFP-EspI and pGFP-EspIΔC7. Analysing the transfected cells by immunofluorescence revealed that Map colocalized with mitochondria (Fig. S1) and NHERF2 (Fig. 3). Plasma membrane-associated EspI and NleH1 colocalized with NHERF2 (Fig. 3). We observed no colocalization of NHERF2 and MapΔC3, EspIΔC7 or NleH1ΔC4 (Fig. S2).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	intact-crc:C3CE4AAF8CD94F23|rigid:uta98I2Rt9s9h2ckdisEtP3ay4M	false	ha tag:?-?	green fluorescent protein tag:?-?	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q15599	uniprotkb:Q8X831	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-16088619|uniprotkb:A0A0H3JEC3|uniprotkb:Q7AGE1	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:q8x831_eco57(display_long)|uniprotkb:nleH1-1(gene name)|psi-mi:nleH1-1(display_short)|uniprotkb:ECs_0848(orf name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25436658|imex:IM-27748-26	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	"refseq:NP_308875.1|refseq:WP_000951026.1|dip:DIP-60658N|go:""GO:0042326""(negative regulation of phosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0140403""(effector-mediated suppression of host innate immune response)|go:""GO:0140416""(transcription regulator inhibitor activity)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4LRJ|mint:Q8X831"	"go:""GO:0005886""(plasma membrane)"	-	-	"figure legend:fig. 3; fig. 6a|comment:""\""In order to determine if the effectors colocalize with NHERF2, HeLa–NHERF2 cells were transfected with pRK5 (Fig. 3) or pRK5 expressing myc-tagged Map, MapΔC3, NleH1 and NleH1ΔC4 as well as pGFP-EspI and pGFP-EspIΔC7. Analysing the transfected cells by immunofluorescence revealed that Map colocalized with mitochondria (Fig. S1) and NHERF2 (Fig. 3). Plasma membrane-associated EspI and NleH1 colocalized with NHERF2 (Fig. 3). We observed no colocalization of NHERF2 and MapΔC3, EspIΔC7 or NleH1ΔC4 (Fig. S2).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:nxwz4f65gXQxF5wdPpZ+bR7YEkw83334	intact-crc:3BCB459CF1552077|rigid:UmffcJjm+itHsg7q5yNS963nxVc	false	ha tag:?-?	myc tag:?-?	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q15599	uniprotkb:B7UMA0	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	intact:EBI-2529418	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	psi-mi:b7uma0_eco27(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:E2348C_3942(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Martinez et al. (2010)	pubmed:20618342|imex:IM-27748	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25436668|imex:IM-27748-28	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	interpro:IPR004959(IpaB/EvcA)|refseq:WP_000492694.1|mint:B7UMA0	"go:""GO:0005739""(mitochondrion)"	-	-	"figure legend:fig. 3 suppl fig. 1|comment:""\""In order to determine if the effectors colocalize with NHERF2, HeLa–NHERF2 cells were transfected with pRK5 (Fig. 3) or pRK5 expressing myc-tagged Map, MapΔC3, NleH1 and NleH1ΔC4 as well as pGFP-EspI and pGFP-EspIΔC7. Analysing the transfected cells by immunofluorescence revealed that Map colocalized with mitochondria (Fig. S1) and NHERF2 (Fig. 3). Plasma membrane-associated EspI and NleH1 colocalized with NHERF2 (Fig. 3). We observed no colocalization of NHERF2 and MapΔC3, EspIΔC7 or NleH1ΔC4 (Fig. S2).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/02/24	2024/11/14	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:K4h+E0YhHOWoenZOShinG380h9E574521	intact-crc:2F25AB795FF20FD9|rigid:9S3jRUFg3rxHblysBY9bbse5hf8	false	ha tag:?-?	myc tag:?-?	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q8X834	uniprotkb:Q04206	intact:EBI-10039193|uniprotkb:A0A7U8R4U9|uniprotkb:Q7AGE2|uniprotkb:A0A6M0JJK4|uniprotkb:A0A6M6W2Q6	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	psi-mi:q8x834_eco57(display_long)|uniprotkb:nleC(gene name)|psi-mi:nleC(display_short)|uniprotkb:ECs_0847(orf name)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Yen et al. (2009)	pubmed:21187904|imex:IM-27757	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25463697|imex:IM-27757-1	intact-miscore:0.59	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025208|go:""GO:0046872""(metal ion binding)|rcsb pdb:4LGI|rcsb pdb:4LGJ|mint:Q8X834|refseq:NP_308874.1"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	-	-	-	"figure legend:fig.4b, 4d|comment:""\""Next, to determine the dependency of this cleavage on host cofactors, purified p65 was mixed with GST-NleC. While both the  p65 only and GST-added control samples showed no change in  total p65 nor the detection of p65-C, the GST-NleC-containing  mixture had less p65, and p65-C was readily detected (Fig. 4B).  Based on these observations, we concluded that NleC could  mediate the direct digestion of p65.\""""|antagonist:""\""EDTA: CHEBI:64758\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/03/03	2025/03/26	rogid:2YRFou+gcur7JjPuYwcTJn7Rrpo83334	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:E6AE1748C4AC7543|rigid:Aa4B/L6wTXHCKeHrhpo3H5iaVEQ	false	glutathione s tranferase tag:?-?|mutation disrupting interaction:196-196	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q8X834	uniprotkb:P19838	intact:EBI-10039193|uniprotkb:A0A7U8R4U9|uniprotkb:Q7AGE2|uniprotkb:A0A6M0JJK4|uniprotkb:A0A6M6W2Q6	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q8x834_eco57(display_long)|uniprotkb:nleC(gene name)|psi-mi:nleC(display_short)|uniprotkb:ECs_0847(orf name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Mühlen et al. (2011)	pubmed:21148319|imex:IM-27769	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25463991|imex:IM-27769-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025208|go:""GO:0046872""(metal ion binding)|rcsb pdb:4LGI|rcsb pdb:4LGJ|mint:Q8X834|refseq:NP_308874.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	-	-	-	figure legend:fig 5a, 6c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/03/03	2025/03/26	rogid:2YRFou+gcur7JjPuYwcTJn7Rrpo83334	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:6A37B0DF1F1602B8|rigid:J9YPPOVdz2hkluO+OtWX+O2kSCU	false	sufficient binding region:1-66|green fluorescent protein tag:?-?|binding-associated region:1-237	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q8X834	uniprotkb:Q04206	intact:EBI-10039193|uniprotkb:A0A7U8R4U9|uniprotkb:Q7AGE2|uniprotkb:A0A6M0JJK4|uniprotkb:A0A6M6W2Q6	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	psi-mi:q8x834_eco57(display_long)|uniprotkb:nleC(gene name)|psi-mi:nleC(display_short)|uniprotkb:ECs_0847(orf name)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Mühlen et al. (2011)	pubmed:21148319|imex:IM-27769	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25463991|imex:IM-27769-1	intact-miscore:0.59	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025208|go:""GO:0046872""(metal ion binding)|rcsb pdb:4LGI|rcsb pdb:4LGJ|mint:Q8X834|refseq:NP_308874.1"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	-	-	-	figure legend:fig 5a, 6c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/03/03	2025/03/26	rogid:2YRFou+gcur7JjPuYwcTJn7Rrpo83334	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:6A37B0DF1F1602B8|rigid:J9YPPOVdz2hkluO+OtWX+O2kSCU	false	sufficient binding region:1-66|green fluorescent protein tag:?-?|binding-associated region:1-237	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P48740-2	uniprotkb:P23827	intact:EBI-26435098|ensembl:ENSP00000296280.7|ensembl:ENSP00000517062.1	intact:EBI-1029159	psi-mi:p48740-2(display_long)|uniprotkb:Mannose-binding protein-associated serine protease(gene name synonym)|uniprotkb:Ra-reactive factor serine protease p100(gene name synonym)|uniprotkb:Serine protease 5(gene name synonym)|uniprotkb:MASP-3(isoform synonym)|uniprotkb:MASP1(gene name)|psi-mi:MASP1(display_short)|uniprotkb:CRARF(gene name synonym)|uniprotkb:CRARF1(gene name synonym)|uniprotkb:PRSS5(gene name synonym)|uniprotkb:Complement factor MASP-3(gene name synonym)|uniprotkb:Complement-activating component of Ra-reactive factor(gene name synonym)|uniprotkb:Mannose-binding lectin-associated serine protease 1(gene name synonym)	psi-mi:ecot_ecoli(display_long)|uniprotkb:eco(gene name)|psi-mi:eco(display_short)|uniprotkb:eti(gene name synonym)|uniprotkb:b2209(locus name)|uniprotkb:JW2197(locus name)	"psi-mi:""MI:0114""(x-ray crystallography)"	Gaboriaud et al. (2012)	imex:IM-29311|pubmed:23861840	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27108908|wwpdb:4IW4|imex:IM-29311-1	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-6380536(isoform-parent)|ensembl:ENSG00000127241.18(gene)|ensembl:ENSG00000291559.1(gene)|ensembl:ENST00000296280.11(transcript)|ensembl:ENST00000707993.1(transcript)	"refseq:NP_416713.1|interpro:IPR005658(Proteinase inhibitor I11, ecotin)|interpro:IPR023084|mint:P23827|interpro:IPR027438|refseq:WP_000849209.1|interpro:IPR036198|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0006952""(defense response)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0042803""(protein homodimerization activity)|rcsb pdb:1AZZ|rcsb pdb:1ECY|rcsb pdb:1ECZ|rcsb pdb:1EZS|rcsb pdb:1EZU|rcsb pdb:1FI8|rcsb pdb:1ID5|rcsb pdb:1IFG|rcsb pdb:1N8O|rcsb pdb:1P0S|rcsb pdb:1SLU|rcsb pdb:1SLV|rcsb pdb:1SLW|rcsb pdb:1SLX|rcsb pdb:1XX9|rcsb pdb:1XXD|rcsb pdb:1XXF|rcsb pdb:4IW4|rcsb pdb:4NIY|rcsb pdb:7CBK|rcsb pdb:7PQN|rcsb pdb:7PQO|panther:PTHR35890(orthology-group)"	-	-	-	figure legend:Table 4|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/17	2024/11/14	rogid:tXsz/6dPTPLuD03oT3LxFm6yDA09606	rogid:ZzO2zrHSsO5iH2kANpN5qFp+S8w83333	intact-crc:E6E705016F4FA07F|rigid:ahWSv0KDuIr+qVPJuOGE7vUzIVU	false	sufficient binding region:450-728	-	2	2	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P48740-2	uniprotkb:P23827	intact:EBI-26435098|ensembl:ENSP00000296280.7|ensembl:ENSP00000517062.1	intact:EBI-1029159	psi-mi:p48740-2(display_long)|uniprotkb:Mannose-binding protein-associated serine protease(gene name synonym)|uniprotkb:Ra-reactive factor serine protease p100(gene name synonym)|uniprotkb:Serine protease 5(gene name synonym)|uniprotkb:MASP-3(isoform synonym)|uniprotkb:MASP1(gene name)|psi-mi:MASP1(display_short)|uniprotkb:CRARF(gene name synonym)|uniprotkb:CRARF1(gene name synonym)|uniprotkb:PRSS5(gene name synonym)|uniprotkb:Complement factor MASP-3(gene name synonym)|uniprotkb:Complement-activating component of Ra-reactive factor(gene name synonym)|uniprotkb:Mannose-binding lectin-associated serine protease 1(gene name synonym)	psi-mi:ecot_ecoli(display_long)|uniprotkb:eco(gene name)|psi-mi:eco(display_short)|uniprotkb:eti(gene name synonym)|uniprotkb:b2209(locus name)|uniprotkb:JW2197(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Gaboriaud et al. (2012)	imex:IM-29311|pubmed:23861840	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27110510|imex:IM-29311-37	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-6380536(isoform-parent)|ensembl:ENSG00000127241.18(gene)|ensembl:ENSG00000291559.1(gene)|ensembl:ENST00000296280.11(transcript)|ensembl:ENST00000707993.1(transcript)	"refseq:NP_416713.1|interpro:IPR005658(Proteinase inhibitor I11, ecotin)|interpro:IPR023084|mint:P23827|interpro:IPR027438|refseq:WP_000849209.1|interpro:IPR036198|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0006952""(defense response)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0042803""(protein homodimerization activity)|rcsb pdb:1AZZ|rcsb pdb:1ECY|rcsb pdb:1ECZ|rcsb pdb:1EZS|rcsb pdb:1EZU|rcsb pdb:1FI8|rcsb pdb:1ID5|rcsb pdb:1IFG|rcsb pdb:1N8O|rcsb pdb:1P0S|rcsb pdb:1SLU|rcsb pdb:1SLV|rcsb pdb:1SLW|rcsb pdb:1SLX|rcsb pdb:1XX9|rcsb pdb:1XXD|rcsb pdb:1XXF|rcsb pdb:4IW4|rcsb pdb:4NIY|rcsb pdb:7CBK|rcsb pdb:7PQN|rcsb pdb:7PQO|panther:PTHR35890(orthology-group)"	-	-	-	figure legend:Figure 3, Table 3.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:601.0x10^-9(molar)	2020/12/17	2024/11/14	rogid:tXsz/6dPTPLuD03oT3LxFm6yDA09606	rogid:ZzO2zrHSsO5iH2kANpN5qFp+S8w83333	intact-crc:C3DB7D180FD13B6E|rigid:ahWSv0KDuIr+qVPJuOGE7vUzIVU	false	sufficient binding region:450-728	-	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O00187	uniprotkb:P23827	intact:EBI-7965040|uniprotkb:Q9UMV3|intact:MINT-7970114|uniprotkb:Q9ULC7|uniprotkb:Q9Y270|uniprotkb:A8MWJ2|uniprotkb:O75754|uniprotkb:Q96QG4|uniprotkb:Q9UBP3|uniprotkb:Q5TEQ5|uniprotkb:Q5TER0|uniprotkb:Q9H498|uniprotkb:Q9UC48|uniprotkb:A8K458|uniprotkb:Q9H499|uniprotkb:Q9BZH0|ensembl:ENSP00000383690.3	intact:EBI-1029159	psi-mi:masp2_human(display_long)|uniprotkb:MASP2(gene name)|psi-mi:MASP2(display_short)|uniprotkb:Mannose-binding protein-associated serine protease 2(gene name synonym)|uniprotkb:MBL-associated serine protease 2(gene name synonym)	psi-mi:ecot_ecoli(display_long)|uniprotkb:eco(gene name)|psi-mi:eco(display_short)|uniprotkb:eti(gene name synonym)|uniprotkb:b2209(locus name)|uniprotkb:JW2197(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Gaboriaud et al. (2012)	imex:IM-29311|pubmed:23861840	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27110517|imex:IM-29311-19	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:331187""|ensembl:ENSG00000009724.18(gene)|ensembl:ENST00000400897.8(transcript)|go:""GO:0001855""(complement component C4b binding)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0008233""(peptidase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR024175|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR043504|interpro:IPR049883|mint:O00187|rcsb pdb:1Q3X|rcsb pdb:1SZB|rcsb pdb:1ZJK|rcsb pdb:3TVJ|rcsb pdb:5JPM|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|reactome:R-HSA-9705671|refseq:NP_006601.2|refseq:NP_631947.1|panther:PTHR24255(orthology-group)"	"refseq:NP_416713.1|interpro:IPR005658(Proteinase inhibitor I11, ecotin)|interpro:IPR023084|mint:P23827|interpro:IPR027438|refseq:WP_000849209.1|interpro:IPR036198|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0006952""(defense response)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0042803""(protein homodimerization activity)|rcsb pdb:1AZZ|rcsb pdb:1ECY|rcsb pdb:1ECZ|rcsb pdb:1EZS|rcsb pdb:1EZU|rcsb pdb:1FI8|rcsb pdb:1ID5|rcsb pdb:1IFG|rcsb pdb:1N8O|rcsb pdb:1P0S|rcsb pdb:1SLU|rcsb pdb:1SLV|rcsb pdb:1SLW|rcsb pdb:1SLX|rcsb pdb:1XX9|rcsb pdb:1XXD|rcsb pdb:1XXF|rcsb pdb:4IW4|rcsb pdb:4NIY|rcsb pdb:7CBK|rcsb pdb:7PQN|rcsb pdb:7PQO|panther:PTHR35890(orthology-group)"	-	comment:mint	-	figure legend:Figure 3, Table 3.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:24.7x10^-9(molar)	2020/12/17	2024/11/14	rogid:S48IDwjdZ8M6vIJD6iM0XplSN609606	rogid:ZzO2zrHSsO5iH2kANpN5qFp+S8w83333	intact-crc:44FD54D35093DDD7|rigid:urXMs5HbUfrMM40dq+KUk1/19xg	false	sufficient binding region:298..298-686..686	-	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
reactome:R-HSA-158234	uniprotkb:P23827	intact:EBI-26356021|reactome:R-HSA-158143|intenz:3.4.21.27	intact:EBI-1029159	psi-mi:f11_human(display_short)|psi-mi:R-HSA-158234(display_long)|intact:FXI complex(complex synonym)|intact:Coagulation factor XIa complex(complex recommended name)|intact:F11 dimer(complex systematic name)|intact:Coagulation factor F11 complex(complex synonym)|intact:FXIa complex(complex synonym)	psi-mi:ecot_ecoli(display_long)|uniprotkb:eco(gene name)|psi-mi:eco(display_short)|uniprotkb:eti(gene name synonym)|uniprotkb:b2209(locus name)|uniprotkb:JW2197(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Gaboriaud et al. (2012)	imex:IM-29311|pubmed:23861840	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27110618|imex:IM-29311-43	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:1302""(stable complex)"	"psi-mi:""MI:0326""(protein)"	"wwpdb:5qtx(exp-evidence)|pubmed:31932224(see-also)|go:""GO:1905370""(serine-type endopeptidase complex)|evidence ontology:""ECO:0000353""|pubmed:12524220(see-also)|go:""GO:0031638""(zymogen activation)|go:""GO:0005615""(extracellular space)|go:""GO:0007597""(blood coagulation, intrinsic pathway)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|efo:""MONDO:0020587""(see-also)|complex portal:CPX-6205(complex-primary)"	"refseq:NP_416713.1|interpro:IPR005658(Proteinase inhibitor I11, ecotin)|interpro:IPR023084|mint:P23827|interpro:IPR027438|refseq:WP_000849209.1|interpro:IPR036198|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0006952""(defense response)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0042803""(protein homodimerization activity)|rcsb pdb:1AZZ|rcsb pdb:1ECY|rcsb pdb:1ECZ|rcsb pdb:1EZS|rcsb pdb:1EZU|rcsb pdb:1FI8|rcsb pdb:1ID5|rcsb pdb:1IFG|rcsb pdb:1N8O|rcsb pdb:1P0S|rcsb pdb:1SLU|rcsb pdb:1SLV|rcsb pdb:1SLW|rcsb pdb:1SLX|rcsb pdb:1XX9|rcsb pdb:1XXD|rcsb pdb:1XXF|rcsb pdb:4IW4|rcsb pdb:4NIY|rcsb pdb:7CBK|rcsb pdb:7PQN|rcsb pdb:7PQO|panther:PTHR35890(orthology-group)"	-	"curated-complex:""\""A serine-type endopeptidase complex of the intrinsic blood coagulation pathway (contact activation pathway). Cleaves Arg-|-Ala and Arg-|-Val bonds of factor IX (P00740) by limited proteolysis to form active factor IXa (CPX-4945) and contributes to factor VIIa-TF complex (CPX-2808) activation. Also binds platelet glycoprotein Ib:IX:V complex. The coagulation pathway is terminated when fibrinogen is cleaved to fibrin which in turn polymerizes to produce a clot.     Its zymogen form is activated by limited proteolysis by factor XIIa (CPX-6209) and thrombin (CPX-6222) to form active factor XIa. Inhibited by antithrombin (SERPINC1, P01008).\""""|complex-assembly:Heterodimer|disease:""\""Factor XI deficiency [MONDO:0020587]: a coagulation disorder characterized by the partial or complete absence of factor XI activity in the blood.\""""|complex-properties:Unlike most coagulation factors, FXIa probably doesn't directly bind calcium."	-	figure legend:Figure 3, Table 3.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.38x10^-9(molar)	2020/12/17	2024/11/14	-	rogid:ZzO2zrHSsO5iH2kANpN5qFp+S8w83333	intact-crc:A7BC10C6AF080E41	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P48740-2	uniprotkb:P23827	intact:EBI-26435098|ensembl:ENSP00000296280.7|ensembl:ENSP00000517062.1	intact:EBI-1029159	psi-mi:p48740-2(display_long)|uniprotkb:Mannose-binding protein-associated serine protease(gene name synonym)|uniprotkb:Ra-reactive factor serine protease p100(gene name synonym)|uniprotkb:Serine protease 5(gene name synonym)|uniprotkb:MASP-3(isoform synonym)|uniprotkb:MASP1(gene name)|psi-mi:MASP1(display_short)|uniprotkb:CRARF(gene name synonym)|uniprotkb:CRARF1(gene name synonym)|uniprotkb:PRSS5(gene name synonym)|uniprotkb:Complement factor MASP-3(gene name synonym)|uniprotkb:Complement-activating component of Ra-reactive factor(gene name synonym)|uniprotkb:Mannose-binding lectin-associated serine protease 1(gene name synonym)	psi-mi:ecot_ecoli(display_long)|uniprotkb:eco(gene name)|psi-mi:eco(display_short)|uniprotkb:eti(gene name synonym)|uniprotkb:b2209(locus name)|uniprotkb:JW2197(locus name)	"psi-mi:""MI:0071""(molecular sieving)"	Gaboriaud et al. (2012)	imex:IM-29311|pubmed:23861840	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27110715|imex:IM-29311-39	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-6380536(isoform-parent)|ensembl:ENSG00000127241.18(gene)|ensembl:ENSG00000291559.1(gene)|ensembl:ENST00000296280.11(transcript)|ensembl:ENST00000707993.1(transcript)	"refseq:NP_416713.1|interpro:IPR005658(Proteinase inhibitor I11, ecotin)|interpro:IPR023084|mint:P23827|interpro:IPR027438|refseq:WP_000849209.1|interpro:IPR036198|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0006952""(defense response)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0042803""(protein homodimerization activity)|rcsb pdb:1AZZ|rcsb pdb:1ECY|rcsb pdb:1ECZ|rcsb pdb:1EZS|rcsb pdb:1EZU|rcsb pdb:1FI8|rcsb pdb:1ID5|rcsb pdb:1IFG|rcsb pdb:1N8O|rcsb pdb:1P0S|rcsb pdb:1SLU|rcsb pdb:1SLV|rcsb pdb:1SLW|rcsb pdb:1SLX|rcsb pdb:1XX9|rcsb pdb:1XXD|rcsb pdb:1XXF|rcsb pdb:4IW4|rcsb pdb:4NIY|rcsb pdb:7CBK|rcsb pdb:7PQN|rcsb pdb:7PQO|panther:PTHR35890(orthology-group)"	-	-	-	figure legend:Figure 4|comment:Peak one.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/17	2024/11/14	rogid:tXsz/6dPTPLuD03oT3LxFm6yDA09606	rogid:ZzO2zrHSsO5iH2kANpN5qFp+S8w83333	intact-crc:49A15425D1680205|rigid:ahWSv0KDuIr+qVPJuOGE7vUzIVU	false	sufficient binding region:450-728	-	2	2	"psi-mi:""MI:0039""(edman degradation)"	"psi-mi:""MI:0039""(edman degradation)"
uniprotkb:P23827-PRO_0000007423	uniprotkb:P48740-2	intact:EBI-27111799	intact:EBI-26435098|ensembl:ENSP00000296280.7|ensembl:ENSP00000517062.1	psi-mi:p23827-pro_0000007423(display_long)|uniprotkb:eco(gene name)|psi-mi:eco(display_short)|uniprotkb:eti(gene name synonym)|uniprotkb:b2209(locus name)|uniprotkb:JW2197(locus name)	psi-mi:p48740-2(display_long)|uniprotkb:Mannose-binding protein-associated serine protease(gene name synonym)|uniprotkb:Ra-reactive factor serine protease p100(gene name synonym)|uniprotkb:Serine protease 5(gene name synonym)|uniprotkb:MASP-3(isoform synonym)|uniprotkb:MASP1(gene name)|psi-mi:MASP1(display_short)|uniprotkb:CRARF(gene name synonym)|uniprotkb:CRARF1(gene name synonym)|uniprotkb:PRSS5(gene name synonym)|uniprotkb:Complement factor MASP-3(gene name synonym)|uniprotkb:Complement-activating component of Ra-reactive factor(gene name synonym)|uniprotkb:Mannose-binding lectin-associated serine protease 1(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Cortesio et al. (2006)	imex:IM-29312|pubmed:16554018	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0570""(protein cleavage)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27111784|imex:IM-29312-21	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-1029159(chain-parent)	intact:EBI-6380536(isoform-parent)|ensembl:ENSG00000127241.18(gene)|ensembl:ENSG00000291559.1(gene)|ensembl:ENST00000296280.11(transcript)|ensembl:ENST00000707993.1(transcript)	-	chain-seq-start:21|chain-seq-end:162	-	figure legend:Table 2|inhibition:Ecotin % inhibition = 98.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/17	2024/11/14	rogid:h73shhX+NPZC1ahdD8pt/IPEBN083333	rogid:tXsz/6dPTPLuD03oT3LxFm6yDA09606	intact-crc:22841A9E61AD7468|rigid:I+20YYfD8KZ2YBktWrTkQful6P4	false	his tag:c-c	sufficient binding region:450-721(IPR001254)|his tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q79GN7	uniprotkb:P05155	intact:EBI-27104360	intact:EBI-1223454|uniprotkb:Q547W3|uniprotkb:Q59EI5|uniprotkb:Q96FE0|uniprotkb:A6NMU0|uniprotkb:A8KAI9|uniprotkb:B2R6L5|uniprotkb:Q16304|uniprotkb:Q7Z455|uniprotkb:Q9UC49|uniprotkb:Q9UCF9|uniprotkb:B4E1F0|uniprotkb:B4E1H2|ensembl:ENSP00000278407.4|ensembl:ENSP00000504807.1	psi-mi:q79gn7_borpe(display_long)|uniprotkb:vag8(gene name)|psi-mi:vag8(display_short)|uniprotkb:BP2315(locus name)	psi-mi:ic1_human(display_long)|uniprotkb:SERPING1(gene name)|psi-mi:SERPING1(display_short)|uniprotkb:C1IN(gene name synonym)|uniprotkb:C1NH(gene name synonym)|uniprotkb:C1 esterase inhibitor(gene name synonym)|uniprotkb:C1-inhibiting factor(gene name synonym)|uniprotkb:Serpin G1(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Wang et al. (2017)	pubmed:28742139|imex:IM-29286	"taxid:257313(borpe)|taxid:257313(""Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27104358|imex:IM-29286-1	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051551|go:""GO:0009279""(cell outer membrane)|refseq:NP_880953.1|refseq:WP_010930866.1|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR036709|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)"	"efo:""Orphanet:100050""|efo:""Orphanet:100051""|refseq:NP_000053.2|refseq:NP_001027466.1|ensembl:ENSG00000149131.17(gene)|ensembl:ENST00000278407.9(transcript)|ensembl:ENST00000676670.1(transcript)|go:""GO:0001869""(negative regulation of complement activation, lectin pathway)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007596""(blood coagulation)|go:""GO:0008015""(blood circulation)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0042730""(fibrinolysis)|go:""GO:0045087""(innate immune response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P05155|rcsb pdb:2OAY|rcsb pdb:5DU3|rcsb pdb:5DUQ|rcsb pdb:7AKV|rcsb pdb:8W18|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-9657689|reactome:R-HSA-977606|dip:DIP-45635N|panther:PTHR11461(orthology-group)"	-	-	-	figure legend:1A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/17	2025/01/01	rogid:1PYDfp3AJnkUkhztQL8kyhBPMC0257313	rogid:Y7cqCZ6Ryz51dsi6jM86EXdfeWc9606	intact-crc:A68B97B730ACFBA6|rigid:pkleNDcsdAG7v4dXC1sus18NtRY	false	sufficient binding region:16-610(IPR011050)|his tag:n-n	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q79GN7	uniprotkb:P05155	intact:EBI-27104360	intact:EBI-1223454|uniprotkb:Q547W3|uniprotkb:Q59EI5|uniprotkb:Q96FE0|uniprotkb:A6NMU0|uniprotkb:A8KAI9|uniprotkb:B2R6L5|uniprotkb:Q16304|uniprotkb:Q7Z455|uniprotkb:Q9UC49|uniprotkb:Q9UCF9|uniprotkb:B4E1F0|uniprotkb:B4E1H2|ensembl:ENSP00000278407.4|ensembl:ENSP00000504807.1	psi-mi:q79gn7_borpe(display_long)|uniprotkb:vag8(gene name)|psi-mi:vag8(display_short)|uniprotkb:BP2315(locus name)	psi-mi:ic1_human(display_long)|uniprotkb:SERPING1(gene name)|psi-mi:SERPING1(display_short)|uniprotkb:C1IN(gene name synonym)|uniprotkb:C1NH(gene name synonym)|uniprotkb:C1 esterase inhibitor(gene name synonym)|uniprotkb:C1-inhibiting factor(gene name synonym)|uniprotkb:Serpin G1(gene name synonym)	"psi-mi:""MI:0071""(molecular sieving)"	Wang et al. (2017)	pubmed:28742139|imex:IM-29286	"taxid:257313(borpe)|taxid:257313(""Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27104389|imex:IM-29286-3	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051551|go:""GO:0009279""(cell outer membrane)|refseq:NP_880953.1|refseq:WP_010930866.1|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR036709|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)"	"efo:""Orphanet:100050""|efo:""Orphanet:100051""|refseq:NP_000053.2|refseq:NP_001027466.1|ensembl:ENSG00000149131.17(gene)|ensembl:ENST00000278407.9(transcript)|ensembl:ENST00000676670.1(transcript)|go:""GO:0001869""(negative regulation of complement activation, lectin pathway)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007596""(blood coagulation)|go:""GO:0008015""(blood circulation)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0042730""(fibrinolysis)|go:""GO:0045087""(innate immune response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P05155|rcsb pdb:2OAY|rcsb pdb:5DU3|rcsb pdb:5DUQ|rcsb pdb:7AKV|rcsb pdb:8W18|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-9657689|reactome:R-HSA-977606|dip:DIP-45635N|panther:PTHR11461(orthology-group)"	-	-	-	figure legend:1B, Supp. figure 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/17	2025/01/01	rogid:1PYDfp3AJnkUkhztQL8kyhBPMC0257313	rogid:Y7cqCZ6Ryz51dsi6jM86EXdfeWc9606	intact-crc:8215D4FA877FC2AD|rigid:pkleNDcsdAG7v4dXC1sus18NtRY	false	sufficient binding region:16-610(IPR011050)|his tag:n-n	-	-	-	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:0113""(western blot)"
uniprotkb:P09871	uniprotkb:Q79GN7	intact:EBI-2810045|uniprotkb:Q9UCU9|uniprotkb:Q9UCV3|uniprotkb:Q9UCU7|uniprotkb:Q9UCV5|uniprotkb:Q9UCV4|uniprotkb:Q9UCU8|uniprotkb:Q9UCV2|uniprotkb:Q9UCV1|uniprotkb:Q9UCV0|uniprotkb:Q9UM14|uniprotkb:D3DUT4|ensembl:ENSP00000328173.3|ensembl:ENSP00000354057.5|ensembl:ENSP00000385035.1	intact:EBI-27104360	psi-mi:c1s_human(display_long)|uniprotkb:C1S(gene name)|psi-mi:C1S(display_short)|uniprotkb:C1 esterase(gene name synonym)|uniprotkb:Complement component 1 subcomponent s(gene name synonym)	psi-mi:q79gn7_borpe(display_long)|uniprotkb:vag8(gene name)|psi-mi:vag8(display_short)|uniprotkb:BP2315(locus name)	"psi-mi:""MI:0807""(comigration in gel electrophoresis)"	Wang et al. (2017)	pubmed:28742139|imex:IM-29286	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:257313(borpe)|taxid:257313(""Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27104407|imex:IM-29286-21	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000182326.17(gene)|ensembl:ENST00000328916.7(transcript)|ensembl:ENST00000360817.10(transcript)|ensembl:ENST00000406697.5(transcript)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0072562""(blood microparticle)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR024175|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR043504|mint:P09871|rcsb pdb:1ELV|rcsb pdb:1NZI|rcsb pdb:4J1Y|rcsb pdb:4LMF|rcsb pdb:4LOR|rcsb pdb:4LOS|rcsb pdb:4LOT|rcsb pdb:6F1C|rcsb pdb:6F1H|rcsb pdb:8GMN|rcsb pdb:8TYP|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|refseq:NP_001333779.1|refseq:NP_001725.1|refseq:NP_958850.1|refseq:XP_005253817.1|efo:""Orphanet:169147""|efo:""Orphanet:75392""|panther:PTHR24255(orthology-group)"	"interpro:IPR051551|go:""GO:0009279""(cell outer membrane)|refseq:NP_880953.1|refseq:WP_010930866.1|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR036709|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)"	-	-	-	figure legend:5B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/17	2025/01/01	rogid:3zz5RwIqLyPO71zdCp5Vx7aVl+Y9606	rogid:1PYDfp3AJnkUkhztQL8kyhBPMC0257313	intact-crc:608D1E314A830681|rigid:o1sZUV+iYvoilaFdt4QzzTX22v0	false	-	sufficient binding region:16-610(IPR011050)|his tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00736	uniprotkb:Q79GN7	intact:EBI-3926504|uniprotkb:A6NJQ8|uniprotkb:Q8J012|uniprotkb:Q68D77	intact:EBI-27104360	psi-mi:c1r_human(display_long)|uniprotkb:C1R(gene name)|psi-mi:C1R(display_short)|uniprotkb:Complement component 1 subcomponent r(gene name synonym)	psi-mi:q79gn7_borpe(display_long)|uniprotkb:vag8(gene name)|psi-mi:vag8(display_short)|uniprotkb:BP2315(locus name)	"psi-mi:""MI:0807""(comigration in gel electrophoresis)"	Wang et al. (2017)	pubmed:28742139|imex:IM-29286	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:257313(borpe)|taxid:257313(""Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27104427|imex:IM-29286-7	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0031638""(zymogen activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0140313""(molecular sequestering activity)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR024175|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR043504|mint:P00736|rcsb pdb:1APQ|rcsb pdb:1GPZ|rcsb pdb:1MD7|rcsb pdb:1MD8|rcsb pdb:2QY0|rcsb pdb:6F1C|rcsb pdb:6F1D|rcsb pdb:6F1H|rcsb pdb:6F39|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|refseq:NP_001724.3|efo:""Orphanet:169147""|efo:""Orphanet:300345""|efo:""Orphanet:75392""|panther:PTHR24255(orthology-group)"	"interpro:IPR051551|go:""GO:0009279""(cell outer membrane)|refseq:NP_880953.1|refseq:WP_010930866.1|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR036709|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)"	-	-	-	figure legend:5 B/C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/17	2025/01/01	rogid:7E+ASC6Hv3CoXdwfWEMwCtYALbw9606	rogid:1PYDfp3AJnkUkhztQL8kyhBPMC0257313	intact-crc:63ECAE203C9EEC53|rigid:52dLJEtTix7izzv3et9/L2998LY	false	-	sufficient binding region:16-610(IPR011050)|his tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05155	uniprotkb:Q79GN7	intact:EBI-1223454|uniprotkb:Q547W3|uniprotkb:Q59EI5|uniprotkb:Q96FE0|uniprotkb:A6NMU0|uniprotkb:A8KAI9|uniprotkb:B2R6L5|uniprotkb:Q16304|uniprotkb:Q7Z455|uniprotkb:Q9UC49|uniprotkb:Q9UCF9|uniprotkb:B4E1F0|uniprotkb:B4E1H2|ensembl:ENSP00000278407.4|ensembl:ENSP00000504807.1	intact:EBI-27104360	psi-mi:ic1_human(display_long)|uniprotkb:SERPING1(gene name)|psi-mi:SERPING1(display_short)|uniprotkb:C1IN(gene name synonym)|uniprotkb:C1NH(gene name synonym)|uniprotkb:C1 esterase inhibitor(gene name synonym)|uniprotkb:C1-inhibiting factor(gene name synonym)|uniprotkb:Serpin G1(gene name synonym)	psi-mi:q79gn7_borpe(display_long)|uniprotkb:vag8(gene name)|psi-mi:vag8(display_short)|uniprotkb:BP2315(locus name)	"psi-mi:""MI:0807""(comigration in gel electrophoresis)"	Wang et al. (2017)	pubmed:28742139|imex:IM-29286	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:257313(borpe)|taxid:257313(""Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27104447|imex:IM-29286-11	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:100050""|efo:""Orphanet:100051""|refseq:NP_000053.2|refseq:NP_001027466.1|ensembl:ENSG00000149131.17(gene)|ensembl:ENST00000278407.9(transcript)|ensembl:ENST00000676670.1(transcript)|go:""GO:0001869""(negative regulation of complement activation, lectin pathway)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007596""(blood coagulation)|go:""GO:0008015""(blood circulation)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0042730""(fibrinolysis)|go:""GO:0045087""(innate immune response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P05155|rcsb pdb:2OAY|rcsb pdb:5DU3|rcsb pdb:5DUQ|rcsb pdb:7AKV|rcsb pdb:8W18|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-9657689|reactome:R-HSA-977606|dip:DIP-45635N|panther:PTHR11461(orthology-group)"	"interpro:IPR051551|go:""GO:0009279""(cell outer membrane)|refseq:NP_880953.1|refseq:WP_010930866.1|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR036709|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)"	-	-	-	figure legend:5 D|comment:Primers for MASP2, in Table 2, only map for the 'reverse' sequence.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/17	2025/01/01	rogid:Y7cqCZ6Ryz51dsi6jM86EXdfeWc9606	rogid:1PYDfp3AJnkUkhztQL8kyhBPMC0257313	intact-crc:33AF841BE86D0AD6|rigid:FCDCnORW7ZgHDi6oiB2DemmaL+g	false	-	sufficient binding region:16-610(IPR011050)|his tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
matrixdb:MULT_83_human	uniprotkb:Q79GN7	intact:EBI-6269273|reactome:R-HSA-173584|reactome:R-HSA-173615|reactome:R-HSA-173617|intenz:3.4.21.42|intenz:3.4.21.41|signor:SIGNOR-C309	intact:EBI-27104360	"psi-mi:c1_human(display_short)|psi-mi:MULT_83_human(display_long)|intact:Complement C1 complex(complex recommended name)|intact:""6xC1QA:6xC1QB:6xC1QC:2xC1R:2xC1S""(complex systematic name)"	psi-mi:q79gn7_borpe(display_long)|uniprotkb:vag8(gene name)|psi-mi:vag8(display_short)|uniprotkb:BP2315(locus name)	"psi-mi:""MI:0807""(comigration in gel electrophoresis)"	Wang et al. (2017)	pubmed:28742139|imex:IM-29286	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:257313(borpe)|taxid:257313(""Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27104538|imex:IM-29286-19	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0586""(inhibitor)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:1302""(stable complex)"	"psi-mi:""MI:0326""(protein)"	"humap:huMAP3_04360.1(subset)|efo:""MONDO:0013419""(see-also)|wwpdb:2wnv(subset)|go:""GO:0005576""(extracellular region)|wwpdb:1PK6(subset)|wwpdb:2jg8(subset)|wwpdb:2jg9(subset)|wwpdb:2wnu(subset)|evidence ontology:""ECO:0005547""|efo:""MONDO:0013343""(see-also)|wwpdb:4LOR(subset)|complex portal:CPX-1920(complex-primary)|wwpdb:6F1C(subset)|pubmed:6250896(see-also)|pubmed:11527969(see-also)|pubmed:28104818(see-also)|go:""GO:0005602""(complement component C1 complex)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0005509""(calcium ion binding)|wwpdb:2QY0(subset)|efo:""MONDO:0007527""(see-also)|pubmed:29311313(see-also)|pubmed:26489954(see-also)"	"interpro:IPR051551|go:""GO:0009279""(cell outer membrane)|refseq:NP_880953.1|refseq:WP_010930866.1|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR036709|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)"	-	"complex-assembly:Hetero 22-mer|disease:""\""Complement component C1q deficiency (C1QD) [MONDO:0013343]: a disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.\""""|disease:""\""Ehlers-Danlos syndrome, periodontal type (EDSPD) [MONDO:0007527]: a form of Ehlers-Danlos syndrome, a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDSPD1 is characterized by the association of typical features of Ehlers-Danlos syndrome with gingival recession and severe early-onset periodontal disease, leading to premature loss of permanent teeth.\""""|disease:""\""Complement component C1s deficiency [MONDO:0013419]: A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.\""""|curated-complex:""\""The first component of the classical serum complement system. In the presence of calcium, the C1q complex (CPX-1919) associates with the C1S-C1R-C1R-C1S tetramer. When C1q binds to an activating target, a conformational change triggers the auto-activation of the associated C1R protease (converting the pro-enzyme into an activated form), which activates C1S. C1S then cleaves the Arg-|-Ala bond in complement component C4 to form C4a and C4b, and the Lys(or Arg)-|-Lys bond in complement component C2 to form C2a and C2b which in turn form C3 convertase complexes C4bC2a-A (CPX-5675) and C4bC2a-B.\""""|complex-properties:2xC1R-2xC1S adopts an extended structure in solution in which the two C1R-C1S dimers are linked by a central interaction between the catalytic domains of C1R. Dimer formation is calcium-dependent, with each heterodimer binding a total of six Ca2+, with a single Ca2+ in each domain. It folds to form a more compact structure to bind to the six collagenous stems of the C1q complex."	-	figure legend:Supp. figure 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/17	2024/11/14	-	rogid:1PYDfp3AJnkUkhztQL8kyhBPMC0257313	intact-crc:3D2E0F65CE10D50D	false	-	sufficient binding region:16-610(IPR011050)|his tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P09871	uniprotkb:Q79GN7	intact:EBI-2810045|uniprotkb:Q9UCU9|uniprotkb:Q9UCV3|uniprotkb:Q9UCU7|uniprotkb:Q9UCV5|uniprotkb:Q9UCV4|uniprotkb:Q9UCU8|uniprotkb:Q9UCV2|uniprotkb:Q9UCV1|uniprotkb:Q9UCV0|uniprotkb:Q9UM14|uniprotkb:D3DUT4|ensembl:ENSP00000328173.3|ensembl:ENSP00000354057.5|ensembl:ENSP00000385035.1	intact:EBI-27104360	psi-mi:c1s_human(display_long)|uniprotkb:C1S(gene name)|psi-mi:C1S(display_short)|uniprotkb:C1 esterase(gene name synonym)|uniprotkb:Complement component 1 subcomponent s(gene name synonym)	psi-mi:q79gn7_borpe(display_long)|uniprotkb:vag8(gene name)|psi-mi:vag8(display_short)|uniprotkb:BP2315(locus name)	"psi-mi:""MI:0435""(protease assay)"	Wang et al. (2017)	pubmed:28742139|imex:IM-29286	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:257313(borpe)|taxid:257313(""Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)"")"	"psi-mi:""MI:0570""(protein cleavage)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-27104478|imex:IM-29286-13	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0840""(stimulator)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000182326.17(gene)|ensembl:ENST00000328916.7(transcript)|ensembl:ENST00000360817.10(transcript)|ensembl:ENST00000406697.5(transcript)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0072562""(blood microparticle)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR024175|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR043504|mint:P09871|rcsb pdb:1ELV|rcsb pdb:1NZI|rcsb pdb:4J1Y|rcsb pdb:4LMF|rcsb pdb:4LOR|rcsb pdb:4LOS|rcsb pdb:4LOT|rcsb pdb:6F1C|rcsb pdb:6F1H|rcsb pdb:8GMN|rcsb pdb:8TYP|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|refseq:NP_001333779.1|refseq:NP_001725.1|refseq:NP_958850.1|refseq:XP_005253817.1|efo:""Orphanet:169147""|efo:""Orphanet:75392""|panther:PTHR24255(orthology-group)"	"interpro:IPR051551|go:""GO:0009279""(cell outer membrane)|refseq:NP_880953.1|refseq:WP_010930866.1|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR036709|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)"	"go:""GO:0004252""(serine-type endopeptidase activity)"	-	-	figure legend:6A|comment:Addition of Vag8 to a purified system consisting of C1-inh, C1s and C2, results in increased cleavage of C2.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/17	2025/01/01	rogid:3zz5RwIqLyPO71zdCp5Vx7aVl+Y9606	rogid:1PYDfp3AJnkUkhztQL8kyhBPMC0257313	intact-crc:05FBC330D157DBFF|rigid:PQUKSkwKtf6FcGQgpPwYu3nLcMA	false	-	sufficient binding region:16-610(IPR011050)|his tag:n-n	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:P9WQP3-PRO_0000000214	uniprotkb:P11226-PRO_0000017401	intact:EBI-26878164	intact:EBI-25427940	"psi-mi:p9wqp3-pro_0000000214(display_long)|uniprotkb:fbpA(gene name)|psi-mi:fbpA(display_short)|uniprotkb:mpt44(gene name synonym)|uniprotkb:MTV026.09c(orf name)|uniprotkb:Rv3804c(locus name)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex A(gene name synonym)|uniprotkb:Fibronectin-binding protein A(gene name synonym)"	psi-mi:p11226-pro_0000017401(display_long)|uniprotkb:Collectin-1(gene name synonym)|uniprotkb:MBP1(gene name synonym)|uniprotkb:Mannan-binding protein(gene name synonym)|uniprotkb:Mannose-binding lectin(gene name synonym)|uniprotkb:MBL2(gene name)|psi-mi:MBL2(display_short)|uniprotkb:COLEC1(gene name synonym)|uniprotkb:MBL(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878129|imex:IM-28818-3	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-26878135(chain-parent)	intact:EBI-5325353(chain-parent)	-	chain-seq-start:44|chain-seq-end:338	chain-seq-start:21|chain-seq-end:248	"figure legend:2B, number 1|comment:""\""weak interaction (Ag85A with MBL).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:Mzt8Fm4pOKzsx7P1aOdMO8CWRag83332	rogid:niwSuVS9f0s8HBqDB7SSsrtneS89606	intact-crc:265A5FF1C5850DEE|rigid:wJVqgTVfNuw8JmKxQFu/En49ICw	false	his tag:c-c	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP3-PRO_0000000214	uniprotkb:O00602-PRO_0000009136	intact:EBI-26878164	intact:EBI-11784425	"psi-mi:p9wqp3-pro_0000000214(display_long)|uniprotkb:fbpA(gene name)|psi-mi:fbpA(display_short)|uniprotkb:mpt44(gene name synonym)|uniprotkb:MTV026.09c(orf name)|uniprotkb:Rv3804c(locus name)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex A(gene name synonym)|uniprotkb:Fibronectin-binding protein A(gene name synonym)"	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878175|imex:IM-28818-21	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-26878135(chain-parent)	intact:EBI-5282479(chain-parent)	-	chain-seq-start:44|chain-seq-end:338	chain-seq-start:30|chain-seq-end:326	figure legend:2B, number 2|comment:Ag85A with Ficolin 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:Mzt8Fm4pOKzsx7P1aOdMO8CWRag83332	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	intact-crc:E44439B786E517EA|rigid:rj5ZQsvw+PtYL6PKj0qW3fLx/1c	false	his tag:c-c	his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP3-PRO_0000000214	uniprotkb:Q15485	intact:EBI-26878164	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744.6	"psi-mi:p9wqp3-pro_0000000214(display_long)|uniprotkb:fbpA(gene name)|psi-mi:fbpA(display_short)|uniprotkb:mpt44(gene name synonym)|uniprotkb:MTV026.09c(orf name)|uniprotkb:Rv3804c(locus name)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex A(gene name synonym)|uniprotkb:Fibronectin-binding protein A(gene name synonym)"	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878185|imex:IM-28818-41	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-26878135(chain-parent)	"refseq:NP_004099.2|refseq:NP_056652.1|panther:PTHR19143(orthology-group)|ensembl:ENSG00000160339.16(gene)|ensembl:ENST00000291744.11(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0008228""(opsonization)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|go:""GO:2001065""(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086"	-	chain-seq-start:44|chain-seq-end:338	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	figure legend:2B, number 3|comment:Ag85A with Ficolin 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:Mzt8Fm4pOKzsx7P1aOdMO8CWRag83332	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	intact-crc:7EB84D7ED03882A1|rigid:ENcDabKR7UQ410z3ScpNmxeKu9c	false	his tag:c-c	his tag:c-c|sufficient binding region:26-313	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP3-PRO_0000000214	uniprotkb:O75636	intact:EBI-26878164	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879.4	"psi-mi:p9wqp3-pro_0000000214(display_long)|uniprotkb:fbpA(gene name)|psi-mi:fbpA(display_short)|uniprotkb:mpt44(gene name synonym)|uniprotkb:MTV026.09c(orf name)|uniprotkb:Rv3804c(locus name)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex A(gene name synonym)|uniprotkb:Fibronectin-binding protein A(gene name synonym)"	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878194|imex:IM-28818-43	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-26878135(chain-parent)	"efo:""Orphanet:331190""|ensembl:ENSG00000142748.14(gene)|ensembl:ENST00000270879.9(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1902679""(negative regulation of RNA biosynthetic process)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|refseq:NP_003656.2|refseq:NP_775628.1|panther:PTHR19143(orthology-group)"	-	chain-seq-start:44|chain-seq-end:338	-	figure legend:2B, number 4|comment:Ag85A with Ficolin 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:Mzt8Fm4pOKzsx7P1aOdMO8CWRag83332	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	intact-crc:3D54EDBA6AA899E4|rigid:lrPubyhgmwqcTkoybAOObXthI5Y	false	his tag:c-c	his tag:c-c|sufficient binding region:22-299	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP1	uniprotkb:P11226-PRO_0000017401	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-25427940	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:p11226-pro_0000017401(display_long)|uniprotkb:Collectin-1(gene name synonym)|uniprotkb:MBP1(gene name synonym)|uniprotkb:Mannan-binding protein(gene name synonym)|uniprotkb:Mannose-binding lectin(gene name synonym)|uniprotkb:MBL2(gene name)|psi-mi:MBL2(display_short)|uniprotkb:COLEC1(gene name synonym)|uniprotkb:MBL(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878214|imex:IM-28818-23	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	intact:EBI-5325353(chain-parent)	-	-	chain-seq-start:21|chain-seq-end:248	"figure legend:2C, 3, number 1|comment:""\""weak interaction (Ag85B with MBL).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:niwSuVS9f0s8HBqDB7SSsrtneS89606	intact-crc:19E449E293F13CE5|rigid:a8BEIwdxTRqTc0e19FCPl24rpjk	false	-	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP1	uniprotkb:O00602-PRO_0000009136	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-11784425	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878254|imex:IM-28818-25	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:2C, 3, number 2|comment:Ag85B with Ficolin 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	intact-crc:EC0CCB51696476EA|rigid:81w4NojGXWr7PfV3tKi5l+LD0sw	false	-	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP1	uniprotkb:Q15485	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744.6	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878260|imex:IM-28818-5	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	"refseq:NP_004099.2|refseq:NP_056652.1|panther:PTHR19143(orthology-group)|ensembl:ENSG00000160339.16(gene)|ensembl:ENST00000291744.11(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0008228""(opsonization)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|go:""GO:2001065""(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086"	-	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	figure legend:2C, 3, number 3|comment:Ag85B with Ficolin 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	intact-crc:895C93F2006F7BA3|rigid:8shUNR4yIHWvmZYzS5Ji2dKoCKc	false	-	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP1	uniprotkb:O75636	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879.4	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878265|imex:IM-28818-7	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	"efo:""Orphanet:331190""|ensembl:ENSG00000142748.14(gene)|ensembl:ENST00000270879.9(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1902679""(negative regulation of RNA biosynthetic process)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|refseq:NP_003656.2|refseq:NP_775628.1|panther:PTHR19143(orthology-group)"	-	-	-	figure legend:2C, 3, number 4|comment:Ag85B with Ficolin 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	intact-crc:67E39676175871CA|rigid:W5F83kFpK9pcJi1AvN5vHvkFkO4	false	-	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP3-PRO_0000000214	uniprotkb:P11226-PRO_0000017401	intact:EBI-26878164	intact:EBI-25427940	"psi-mi:p9wqp3-pro_0000000214(display_long)|uniprotkb:fbpA(gene name)|psi-mi:fbpA(display_short)|uniprotkb:mpt44(gene name synonym)|uniprotkb:MTV026.09c(orf name)|uniprotkb:Rv3804c(locus name)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex A(gene name synonym)|uniprotkb:Fibronectin-binding protein A(gene name synonym)"	psi-mi:p11226-pro_0000017401(display_long)|uniprotkb:Collectin-1(gene name synonym)|uniprotkb:MBP1(gene name synonym)|uniprotkb:Mannan-binding protein(gene name synonym)|uniprotkb:Mannose-binding lectin(gene name synonym)|uniprotkb:MBL2(gene name)|psi-mi:MBL2(display_short)|uniprotkb:COLEC1(gene name synonym)|uniprotkb:MBL(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878480|imex:IM-28818-13	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-26878135(chain-parent)	intact:EBI-5325353(chain-parent)	-	chain-seq-start:44|chain-seq-end:338	chain-seq-start:21|chain-seq-end:248	"figure legend:6|comment:""\""weak interaction (Ag85A with MBL).\""""|comment:""\""Approximately 60% of d‐mannose in solution occurs in the crystallized form of alpha‐d‐pyranose (CHEBI:28729), and the rest occurs in the form of beta‐d‐pyranose (CHEBI:28563).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:Mzt8Fm4pOKzsx7P1aOdMO8CWRag83332	rogid:niwSuVS9f0s8HBqDB7SSsrtneS89606	intact-crc:A51F45F5E3EB43A2	false	his tag:c-c	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP3-PRO_0000000214	uniprotkb:O00602-PRO_0000009136	intact:EBI-26878164	intact:EBI-11784425	"psi-mi:p9wqp3-pro_0000000214(display_long)|uniprotkb:fbpA(gene name)|psi-mi:fbpA(display_short)|uniprotkb:mpt44(gene name synonym)|uniprotkb:MTV026.09c(orf name)|uniprotkb:Rv3804c(locus name)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex A(gene name synonym)|uniprotkb:Fibronectin-binding protein A(gene name synonym)"	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878568|imex:IM-28818-15	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-26878135(chain-parent)	intact:EBI-5282479(chain-parent)	-	chain-seq-start:44|chain-seq-end:338	chain-seq-start:30|chain-seq-end:326	figure legend:6|comment:Ag85A with Ficolin 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:Mzt8Fm4pOKzsx7P1aOdMO8CWRag83332	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	intact-crc:0DD3922C6FF06520|rigid:CWz8fZSRy0y5ZajvKeTKWyVeyV8	false	his tag:c-c	his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP3-PRO_0000000214	uniprotkb:Q15485	intact:EBI-26878164	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744.6	"psi-mi:p9wqp3-pro_0000000214(display_long)|uniprotkb:fbpA(gene name)|psi-mi:fbpA(display_short)|uniprotkb:mpt44(gene name synonym)|uniprotkb:MTV026.09c(orf name)|uniprotkb:Rv3804c(locus name)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex A(gene name synonym)|uniprotkb:Fibronectin-binding protein A(gene name synonym)"	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878582|imex:IM-28818-33	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-26878135(chain-parent)	"refseq:NP_004099.2|refseq:NP_056652.1|panther:PTHR19143(orthology-group)|ensembl:ENSG00000160339.16(gene)|ensembl:ENST00000291744.11(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0008228""(opsonization)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|go:""GO:2001065""(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086"	-	chain-seq-start:44|chain-seq-end:338	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	figure legend:6|comment:Ag85A with Ficolin 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:Mzt8Fm4pOKzsx7P1aOdMO8CWRag83332	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	intact-crc:A4C3071B7AEEA51B|rigid:X23JwOz6SBztap/QrVcZKtnERhA	false	his tag:c-c	his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP3-PRO_0000000214	uniprotkb:O75636	intact:EBI-26878164	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879.4	"psi-mi:p9wqp3-pro_0000000214(display_long)|uniprotkb:fbpA(gene name)|psi-mi:fbpA(display_short)|uniprotkb:mpt44(gene name synonym)|uniprotkb:MTV026.09c(orf name)|uniprotkb:Rv3804c(locus name)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex A(gene name synonym)|uniprotkb:Fibronectin-binding protein A(gene name synonym)"	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878624|imex:IM-28818-51	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	intact:EBI-26878135(chain-parent)	"efo:""Orphanet:331190""|ensembl:ENSG00000142748.14(gene)|ensembl:ENST00000270879.9(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1902679""(negative regulation of RNA biosynthetic process)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|refseq:NP_003656.2|refseq:NP_775628.1|panther:PTHR19143(orthology-group)"	-	chain-seq-start:44|chain-seq-end:338	-	figure legend:6|comment:Ag85A with Ficolin 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:Mzt8Fm4pOKzsx7P1aOdMO8CWRag83332	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	intact-crc:3BD85E4E04C7DDD6	false	his tag:c-c	his tag:c-c|sufficient binding region:22-299	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P02751	uniprotkb:P9WQP3-PRO_0000000214	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-26878164	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:p9wqp3-pro_0000000214(display_long)|uniprotkb:fbpA(gene name)|psi-mi:fbpA(display_short)|uniprotkb:mpt44(gene name synonym)|uniprotkb:MTV026.09c(orf name)|uniprotkb:Rv3804c(locus name)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex A(gene name synonym)|uniprotkb:Fibronectin-binding protein A(gene name synonym)"	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26880710|imex:IM-28818-53	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	intact:EBI-26878135(chain-parent)	-	-	chain-seq-start:44|chain-seq-end:338	figure legend:8B|comment:Fibronectin interacting with Ag85A; Ficolin 3 as competitor/inhibitor.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2025/03/25	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:Mzt8Fm4pOKzsx7P1aOdMO8CWRag83332	intact-crc:42D50C9BEE72AB06|rigid:ZlNzepozXTlaZ9+kgsDE01Ncz3c	false	-	his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P02751	uniprotkb:P9WQP3-PRO_0000000214	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-26878164	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:p9wqp3-pro_0000000214(display_long)|uniprotkb:fbpA(gene name)|psi-mi:fbpA(display_short)|uniprotkb:mpt44(gene name synonym)|uniprotkb:MTV026.09c(orf name)|uniprotkb:Rv3804c(locus name)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex A(gene name synonym)|uniprotkb:Fibronectin-binding protein A(gene name synonym)"	"psi-mi:""MI:0892""(solid phase assay)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26880722|imex:IM-28818-55	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	intact:EBI-26878135(chain-parent)	-	-	chain-seq-start:44|chain-seq-end:338	figure legend:8C|comment:Fibronectin interacting with  Ficolin 3;Ag85A as  a competitor/inhibitor.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2025/03/25	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:Mzt8Fm4pOKzsx7P1aOdMO8CWRag83332	intact-crc:61092CE8F620D75C|rigid:ZlNzepozXTlaZ9+kgsDE01Ncz3c	false	-	his tag:c-c	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P9WQP1	uniprotkb:P11226-PRO_0000017401	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-25427940	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:p11226-pro_0000017401(display_long)|uniprotkb:Collectin-1(gene name synonym)|uniprotkb:MBP1(gene name synonym)|uniprotkb:Mannan-binding protein(gene name synonym)|uniprotkb:Mannose-binding lectin(gene name synonym)|uniprotkb:MBL2(gene name)|psi-mi:MBL2(display_short)|uniprotkb:COLEC1(gene name synonym)|uniprotkb:MBL(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878286|imex:IM-28818-9	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	intact:EBI-5325353(chain-parent)	-	-	chain-seq-start:21|chain-seq-end:248	figure legend:4|comment:Ag85B with MBL|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:niwSuVS9f0s8HBqDB7SSsrtneS89606	intact-crc:7E76830263C1E584|rigid:a8BEIwdxTRqTc0e19FCPl24rpjk	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P9WQP1	uniprotkb:O00602-PRO_0000009136	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-11784425	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878291|imex:IM-28818-11	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:4|comment:Ag85B with Ficolin 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	intact-crc:142AC58017324265|rigid:81w4NojGXWr7PfV3tKi5l+LD0sw	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P9WQP1	uniprotkb:Q15485	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744.6	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878296|imex:IM-28818-29	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	"refseq:NP_004099.2|refseq:NP_056652.1|panther:PTHR19143(orthology-group)|ensembl:ENSG00000160339.16(gene)|ensembl:ENST00000291744.11(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0008228""(opsonization)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|go:""GO:2001065""(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086"	-	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	figure legend:4|comment:Ag85B with Ficolin 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	intact-crc:229156F022309791|rigid:8shUNR4yIHWvmZYzS5Ji2dKoCKc	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P9WQP1	uniprotkb:O75636	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879.4	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878301|imex:IM-28818-31	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	"efo:""Orphanet:331190""|ensembl:ENSG00000142748.14(gene)|ensembl:ENST00000270879.9(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1902679""(negative regulation of RNA biosynthetic process)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|refseq:NP_003656.2|refseq:NP_775628.1|panther:PTHR19143(orthology-group)"	-	-	-	figure legend:4|comment:Ag85B with Ficolin 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	intact-crc:E7D6B66AD8226537|rigid:W5F83kFpK9pcJi1AvN5vHvkFkO4	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P9WQP1	uniprotkb:O00602-PRO_0000009136	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-11784425	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878402|imex:IM-28818-45	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:5, Table 1|comment:Ag85B with Ficolin 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.3x10^-8(molar)	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	intact-crc:2788105D861B12A8|rigid:81w4NojGXWr7PfV3tKi5l+LD0sw	false	-	-	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P9WQP1	uniprotkb:Q15485	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744.6	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878407|imex:IM-28818-47	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	"refseq:NP_004099.2|refseq:NP_056652.1|panther:PTHR19143(orthology-group)|ensembl:ENSG00000160339.16(gene)|ensembl:ENST00000291744.11(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0008228""(opsonization)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|go:""GO:2001065""(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086"	-	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	figure legend:5, table 1|comment:Ag85B with Ficolin 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.2x10^-8(molar)	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	intact-crc:AC86990317316160|rigid:8shUNR4yIHWvmZYzS5Ji2dKoCKc	false	-	-	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P9WQP1	uniprotkb:O75636	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879.4	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26878412|imex:IM-28818-49	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	"efo:""Orphanet:331190""|ensembl:ENSG00000142748.14(gene)|ensembl:ENST00000270879.9(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1902679""(negative regulation of RNA biosynthetic process)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|refseq:NP_003656.2|refseq:NP_775628.1|panther:PTHR19143(orthology-group)"	-	-	-	figure legend:5, Table 1|comment:Ag85B with Ficolin 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.8x10^-8(molar)	2020/12/18	2024/11/14	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	intact-crc:7B8A30D4DA46999A|rigid:W5F83kFpK9pcJi1AvN5vHvkFkO4	false	-	-	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75636	uniprotkb:P9WQP1	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879.4	intact:EBI-26878221|uniprotkb:D6MJP5|uniprotkb:F2GHQ8|uniprotkb:P0C5B9|uniprotkb:P31952|uniprotkb:Q9RMI0	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	"psi-mi:a85b_myctu(display_long)|uniprotkb:fbpB(gene name)|psi-mi:fbpB(display_short)|uniprotkb:30 kDa extracellular protein(gene name synonym)|uniprotkb:""Acyl-CoA:diacylglycerol acyltransferase""(gene name synonym)|uniprotkb:Antigen 85 complex B(gene name synonym)|uniprotkb:Extracellular alpha-antigen(gene name synonym)|uniprotkb:Fibronectin-binding protein B(gene name synonym)|uniprotkb:MTCY180.32(orf name)|uniprotkb:Rv1886c(locus name)"	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Świerzko et al. (2016)	imex:IM-28818|pubmed:27141819	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-26880611|imex:IM-28818-17	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:331190""|ensembl:ENSG00000142748.14(gene)|ensembl:ENST00000270879.9(transcript)|go:""GO:0001867""(complement activation, lectin pathway)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0003823""(antigen binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0043654""(recognition of apoptotic cell)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0072562""(blood microparticle)|go:""GO:0097367""(carbohydrate derivative binding)|go:""GO:1902679""(negative regulation of RNA biosynthetic process)|go:""GO:1903028""(positive regulation of opsonization)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR050373|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|refseq:NP_003656.2|refseq:NP_775628.1|panther:PTHR19143(orthology-group)"	"interpro:IPR050583|go:""GO:0001968""(fibronectin binding)|go:""GO:0004144""(diacylglycerol O-acyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009274""(peptidoglycan-based cell wall)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0035375""(zymogen binding)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050348""(trehalose O-mycolyltransferase activity)|go:""GO:0052572""(response to host immune response)|refseq:NP_216402.1|refseq:WP_003409456.1|rcsb pdb:1F0N|rcsb pdb:1F0P|rcsb pdb:5TRZ|rcsb pdb:5TS1|interpro:IPR029058|interpro:IPR000801(Putative esterase)|panther:PTHR48098(orthology-group)"	-	-	-	"figure legend:7|comment:Ag85B with Ficolin 3|comment:""\""Weak interaction; Text states:-\\""The black arrow (A panel) marks a subtle band suspected to correspond to Ag85.\\""\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.8x10^-8(molar)	2020/12/18	2024/11/14	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rogid:5szrASs87LZuw0JpQGKhPP+lcFU83332	intact-crc:F6CE31FD3DA8D231|rigid:W5F83kFpK9pcJi1AvN5vHvkFkO4	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P0AA10	uniprotkb:Q9BYD3	intact:EBI-543801|uniprotkb:P02410|uniprotkb:Q2M8Y2	intact:EBI-721368|uniprotkb:A6NNV7|uniprotkb:Q9BW07|uniprotkb:Q9H4N2|uniprotkb:Q9Y317|ensembl:ENSP00000253099.5|ensembl:ENSP00000306902.5	psi-mi:rl13_ecoli(display_long)|uniprotkb:rplM(gene name)|psi-mi:rplM(display_short)|uniprotkb:50S ribosomal protein L13(gene name synonym)|uniprotkb:JW3200(locus name)|uniprotkb:b3231(locus name)	psi-mi:rm04_human(display_long)|uniprotkb:MRPL4(gene name)|psi-mi:MRPL4(display_short)|uniprotkb:39S ribosomal protein L4, mitochondrial(gene name synonym)|uniprotkb:CDABP0091(orf name)|uniprotkb:CGI-28(orf name)	"psi-mi:""MI:0410""(3D electron microscopy)"	Sharma et al. (2009)	imex:IM-28866|pubmed:19497863	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-26574923|wwpdb:3IY9|emdb:EMD-5113|imex:IM-28866-3	intact-miscore:0.32	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_417698.1|refseq:WP_000847559.1|dip:DIP-47837N|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003729""(mRNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0008270""(zinc ion binding)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0022625""(cytosolic large ribosomal subunit)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0070180""(large ribosomal subunit rRNA binding)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR005823(Ribosomal protein L13, bacterial-type)|interpro:IPR023563|interpro:IPR036899|rcsb pdb:1ML5|rcsb pdb:2J28|rcsb pdb:2RDO|rcsb pdb:3BBX|rcsb pdb:3IY9|rcsb pdb:3J5L|rcsb pdb:3J7Z|rcsb pdb:3J8G|rcsb pdb:3J9Y|rcsb pdb:3J9Z|rcsb pdb:3JA1|rcsb pdb:3JBU|rcsb pdb:3JBV|rcsb pdb:3JCD|rcsb pdb:3JCE|rcsb pdb:3JCJ|rcsb pdb:3JCN|rcsb pdb:4CSU|rcsb pdb:4U1U|rcsb pdb:4U1V|rcsb pdb:4U20|rcsb pdb:4U24|rcsb pdb:4U25|rcsb pdb:4U26|rcsb pdb:4U27|rcsb pdb:4UY8|rcsb pdb:4V47|rcsb pdb:4V48|rcsb pdb:4V4H|rcsb pdb:4V4Q|rcsb pdb:4V4V|rcsb pdb:4V4W|rcsb pdb:4V50|rcsb pdb:4V52|rcsb pdb:4V53|rcsb pdb:4V54|rcsb pdb:4V55|rcsb pdb:4V56|rcsb pdb:4V57|rcsb pdb:4V5B|rcsb pdb:4V5H|rcsb pdb:4V5Y|rcsb pdb:4V64|rcsb pdb:4V65|rcsb pdb:4V66|rcsb pdb:4V69|rcsb pdb:4V6C|rcsb pdb:4V6D|rcsb pdb:4V6E|rcsb pdb:4V6K|rcsb pdb:4V6L|rcsb pdb:4V6M|rcsb pdb:4V6N|rcsb pdb:4V6O|rcsb pdb:4V6P|rcsb pdb:4V6Q|rcsb pdb:4V6R|rcsb pdb:4V6S|rcsb pdb:4V6T|rcsb pdb:4V6V|rcsb pdb:4V6Y|rcsb pdb:4V6Z|rcsb pdb:4V70|rcsb pdb:4V71|rcsb pdb:4V72|rcsb pdb:4V73|rcsb pdb:4V74|rcsb pdb:4V75|rcsb pdb:4V76|rcsb pdb:4V77|rcsb pdb:4V78|rcsb pdb:4V79|rcsb pdb:4V7A|rcsb pdb:4V7B|rcsb pdb:4V7C|rcsb pdb:4V7D|rcsb pdb:4V7I|rcsb pdb:4V7S|rcsb pdb:4V7T|rcsb pdb:4V7U|rcsb pdb:4V7V|rcsb pdb:4V85|rcsb pdb:4V89|rcsb pdb:4V9C|rcsb pdb:4V9D|rcsb pdb:4V9O|rcsb pdb:4V9P|rcsb pdb:4WF1|rcsb pdb:4WOI|rcsb pdb:4WWW|rcsb pdb:4YBB|rcsb pdb:5ADY|rcsb pdb:5AFI|rcsb pdb:5AKA|rcsb pdb:5GAD|rcsb pdb:5GAE|rcsb pdb:5GAF|rcsb pdb:5GAG|rcsb pdb:5GAH|rcsb pdb:5H5U|rcsb pdb:5IQR|rcsb pdb:5IT8|rcsb pdb:5J5B|rcsb pdb:5J7L|rcsb pdb:5J88|rcsb pdb:5J8A|rcsb pdb:5J91|rcsb pdb:5JC9|rcsb pdb:5JTE|rcsb pdb:5JU8|rcsb pdb:5KCR|rcsb pdb:5KCS|rcsb pdb:5KPS|rcsb pdb:5KPV|rcsb pdb:5KPW|rcsb pdb:5KPX|rcsb pdb:5L3P|rcsb pdb:5LZA|rcsb pdb:5LZB|rcsb pdb:5LZC|rcsb pdb:5LZD|rcsb pdb:5LZE|rcsb pdb:5LZF|rcsb pdb:5MDV|rcsb pdb:5MDW|rcsb pdb:5MDY|rcsb pdb:5MDZ|rcsb pdb:5MGP|rcsb pdb:5NCO|rcsb pdb:5NP6|rcsb pdb:5NWY|rcsb pdb:5O2R|rcsb pdb:5U4I|rcsb pdb:5U9F|rcsb pdb:5U9G|rcsb pdb:5UYK|rcsb pdb:5UYL|rcsb pdb:5UYM|rcsb pdb:5UYN|rcsb pdb:5UYP|rcsb pdb:5UYQ|rcsb pdb:5WDT|rcsb pdb:5WE4|rcsb pdb:5WE6|rcsb pdb:5WF0|rcsb pdb:5WFK|rcsb pdb:5WFS|rcsb pdb:6BU8|rcsb pdb:6BY1|rcsb pdb:6C4I|rcsb pdb:6DNC|rcsb pdb:6ENF|rcsb pdb:6ENJ|rcsb pdb:6ENU|rcsb pdb:6GBZ|rcsb pdb:6GC0|rcsb pdb:6GC4|rcsb pdb:6GC6|rcsb pdb:6GC7|rcsb pdb:6GC8|rcsb pdb:6GWT|rcsb pdb:6GXM|rcsb pdb:6GXN|rcsb pdb:6GXO|rcsb pdb:6GXP|rcsb pdb:6H4N|rcsb pdb:6H58|rcsb pdb:6HRM|rcsb pdb:6I0Y|rcsb pdb:6I7V|rcsb pdb:6O9J|rcsb pdb:6O9K|rcsb pdb:6OFX|rcsb pdb:6OG7|rcsb pdb:6OGF|rcsb pdb:6OGG|rcsb pdb:6OGI|rcsb pdb:6OM6|rcsb pdb:6ORE|rcsb pdb:6ORL|rcsb pdb:6OSK|rcsb pdb:6OSQ|rcsb pdb:6OST|rcsb pdb:6OT3|rcsb pdb:6OUO|rcsb pdb:6PC5|rcsb pdb:6PC6|rcsb pdb:6PC7|rcsb pdb:6PC8|rcsb pdb:6PCH|rcsb pdb:6PCQ|rcsb pdb:6PCR|rcsb pdb:6PCS|rcsb pdb:6PCT|rcsb pdb:6PJ6|rcsb pdb:6Q98|rcsb pdb:6Q9A|rcsb pdb:6QDW|rcsb pdb:6QUL|rcsb pdb:6S0K|rcsb pdb:6SZS|rcsb pdb:6TBV|rcsb pdb:6TC3|rcsb pdb:6U48|rcsb pdb:6VU3|rcsb pdb:6VWL|rcsb pdb:6VWM|rcsb pdb:6VWN|rcsb pdb:6VYQ|rcsb pdb:6VYR|rcsb pdb:6VYS|rcsb pdb:6VYT|rcsb pdb:6VYU|rcsb pdb:6VYW|rcsb pdb:6VYX|rcsb pdb:6VYY|rcsb pdb:6VYZ|rcsb pdb:6VZ2|rcsb pdb:6VZ3|rcsb pdb:6VZ5|rcsb pdb:6VZ7|rcsb pdb:6VZJ|rcsb pdb:6WD0|rcsb pdb:6WD1|rcsb pdb:6WD2|rcsb pdb:6WD3|rcsb pdb:6WD4|rcsb pdb:6WD5|rcsb pdb:6WD6|rcsb pdb:6WD7|rcsb pdb:6WD8|rcsb pdb:6WD9|rcsb pdb:6WDA|rcsb pdb:6WDB|rcsb pdb:6WDC|rcsb pdb:6WDD|rcsb pdb:6WDE|rcsb pdb:6WDF|rcsb pdb:6WDG|rcsb pdb:6WDH|rcsb pdb:6WDI|rcsb pdb:6WDJ|rcsb pdb:6WDK|rcsb pdb:6WDL|rcsb pdb:6WDM|rcsb pdb:6WNT|rcsb pdb:6WNV|rcsb pdb:6WNW|rcsb pdb:6WYV|rcsb pdb:6X6T|rcsb pdb:6X7F|rcsb pdb:6X7K|rcsb pdb:6X9Q|rcsb pdb:6XDQ|rcsb pdb:6XDR|rcsb pdb:6XGF|rcsb pdb:6XII|rcsb pdb:6XIJ|rcsb pdb:6XZ7|rcsb pdb:6XZA|rcsb pdb:6XZB|rcsb pdb:6Y69|rcsb pdb:6YS3|rcsb pdb:6YSR|rcsb pdb:6YSS|rcsb pdb:6YST|rcsb pdb:6YSU|rcsb pdb:6ZTJ|rcsb pdb:6ZTL|rcsb pdb:6ZTM|rcsb pdb:6ZTN|rcsb pdb:6ZTO|rcsb pdb:6ZTP|rcsb pdb:6ZU1|rcsb pdb:7ABZ|rcsb pdb:7AC7|rcsb pdb:7ACJ|rcsb pdb:7ACR|rcsb pdb:7B5K|rcsb pdb:7BL2|rcsb pdb:7BL3|rcsb pdb:7BL4|rcsb pdb:7BL5|rcsb pdb:7BL6|rcsb pdb:7BV8|rcsb pdb:7D6Z|rcsb pdb:7D80|rcsb pdb:7JSS|rcsb pdb:7JSW|rcsb pdb:7JSZ|rcsb pdb:7JT1|rcsb pdb:7JT2|rcsb pdb:7JT3|rcsb pdb:7K00|rcsb pdb:7K50|rcsb pdb:7K51|rcsb pdb:7K52|rcsb pdb:7K53|rcsb pdb:7K54|rcsb pdb:7K55|rcsb pdb:7LV0|rcsb pdb:7LVK|rcsb pdb:7M5D|rcsb pdb:7N1P|rcsb pdb:7N2C|rcsb pdb:7N2U|rcsb pdb:7N2V|rcsb pdb:7N30|rcsb pdb:7N31|rcsb pdb:7NBU|rcsb pdb:7NSO|rcsb pdb:7NSP|rcsb pdb:7NSQ|rcsb pdb:7NWT|rcsb pdb:7NWW|rcsb pdb:7O19|rcsb pdb:7O1A|rcsb pdb:7O1C|rcsb pdb:7ODE|rcsb pdb:7OIF|rcsb pdb:7OIG|rcsb pdb:7OII|rcsb pdb:7OIZ|rcsb pdb:7OJ0|rcsb pdb:7OT5|rcsb pdb:7P3K|rcsb pdb:7PJS|rcsb pdb:7PJT|rcsb pdb:7PJV|rcsb pdb:7PJW|rcsb pdb:7PJX|rcsb pdb:7PJY|rcsb pdb:7PJZ|rcsb pdb:7Q4K|rcsb pdb:7QG8|rcsb pdb:7QGH|rcsb pdb:7QGN|rcsb pdb:7QGR|rcsb pdb:7QQ3|rcsb pdb:7S1G|rcsb pdb:7S1H|rcsb pdb:7S1I|rcsb pdb:7S1J|rcsb pdb:7S1K|rcsb pdb:7SA4|rcsb pdb:7SS9|rcsb pdb:7SSD|rcsb pdb:7SSL|rcsb pdb:7SSN|rcsb pdb:7SSO|rcsb pdb:7SSW|rcsb pdb:7ST2|rcsb pdb:7ST6|rcsb pdb:7ST7|rcsb pdb:7TOS|rcsb pdb:7UG7|rcsb pdb:7UPH|rcsb pdb:7Y7C|rcsb pdb:7Y7D|rcsb pdb:7Y7E|rcsb pdb:7Y7F|rcsb pdb:7Y7G|rcsb pdb:7Y7H|rcsb pdb:7YLA|rcsb pdb:7Z20|rcsb pdb:7ZOD|rcsb pdb:7ZP8|rcsb pdb:7ZQ5|rcsb pdb:7ZQ6|rcsb pdb:7ZTA|rcsb pdb:8A3L|rcsb pdb:8AKN|rcsb pdb:8AM9|rcsb pdb:8ANA|rcsb pdb:8AP4|rcsb pdb:8AYE|rcsb pdb:8B0X|rcsb pdb:8B7Y|rcsb pdb:8BF7|rcsb pdb:8BGE|rcsb pdb:8BGH|rcsb pdb:8BH4|rcsb pdb:8BHJ|rcsb pdb:8BHL|rcsb pdb:8BHN|rcsb pdb:8BHP|rcsb pdb:8BIL|rcsb pdb:8BIM|rcsb pdb:8C8X|rcsb pdb:8C8Y|rcsb pdb:8C8Z|rcsb pdb:8C90|rcsb pdb:8C91|rcsb pdb:8C92|rcsb pdb:8C93|rcsb pdb:8C94|rcsb pdb:8C95|rcsb pdb:8C96|rcsb pdb:8C98|rcsb pdb:8C99|rcsb pdb:8CAM|rcsb pdb:8CEU|rcsb pdb:8CGD|rcsb pdb:8CGK|rcsb pdb:8CGV|rcsb pdb:8E30|rcsb pdb:8E32|rcsb pdb:8E33|rcsb pdb:8E35|rcsb pdb:8E36|rcsb pdb:8E3L|rcsb pdb:8E3M|rcsb pdb:8E3O|rcsb pdb:8E41|rcsb pdb:8E42|rcsb pdb:8E43|rcsb pdb:8E44|rcsb pdb:8E45|rcsb pdb:8E46|rcsb pdb:8E47|rcsb pdb:8E48|rcsb pdb:8E49|rcsb pdb:8EIU|rcsb pdb:8EKC|rcsb pdb:8EMM|rcsb pdb:8FIZ|rcsb pdb:8FTO|rcsb pdb:8G2U|rcsb pdb:8G31|rcsb pdb:8G34|rcsb pdb:8G38|rcsb pdb:8G6W|rcsb pdb:8G6X|rcsb pdb:8G6Y|rcsb pdb:8G7P|rcsb pdb:8G7Q|rcsb pdb:8G7R|rcsb pdb:8G7S|rcsb pdb:8HSP|rcsb pdb:8HTZ|rcsb pdb:8HU1|rcsb pdb:8IFB|rcsb pdb:8IFC|rcsb pdb:8J1Z|rcsb pdb:8P16|rcsb pdb:8P17|rcsb pdb:8P18|rcsb pdb:8PEG|rcsb pdb:8PHJ|rcsb pdb:8PKL|rcsb pdb:8PVA|rcsb pdb:8Q4F|rcsb pdb:8QBT|rcsb pdb:8QK7|rcsb pdb:8QOA|rcsb pdb:8R6C|rcsb pdb:8R8M|rcsb pdb:8RPY|rcsb pdb:8RPZ|rcsb pdb:8RQ0|rcsb pdb:8RQ2|rcsb pdb:8SYL|rcsb pdb:8W51|rcsb pdb:9CL9|rcsb pdb:9FBV|panther:PTHR11545(orthology-group)"	"refseq:NP_057040.2|refseq:NP_666499.1|refseq:NP_666500.1|ensembl:ENSG00000105364.14(gene)|ensembl:ENST00000253099.11(transcript)|ensembl:ENST00000307422.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005762""(mitochondrial large ribosomal subunit)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013005(Ribosomal protein L4/L1e, bacterial-type)|interpro:IPR023574|mint:Q9BYD3|rcsb pdb:3IY9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:7OI6|rcsb pdb:7OI7|rcsb pdb:7OI8|rcsb pdb:7OI9|rcsb pdb:7OIA|rcsb pdb:7OIB|rcsb pdb:7OIC|rcsb pdb:7OID|rcsb pdb:7OIE|rcsb pdb:7PD3|rcsb pdb:7PO4|rcsb pdb:7QH6|rcsb pdb:7QH7|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8K2A|rcsb pdb:8K2B|rcsb pdb:8OIR|rcsb pdb:8OIT|rcsb pdb:8PK0|rcsb pdb:8QSJ|rcsb pdb:8QU1|rcsb pdb:8QU5|rcsb pdb:8XT0|rcsb pdb:8XT1|rcsb pdb:8XT2|rcsb pdb:8XT3|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR10746(orthology-group)"	-	-	-	figure legend:Fig 3, Fig S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/30	2024/11/14	rogid:z77fcwIBr2DCHbFKdrqVqN1bibU83333	rogid:v1MODeAQQcG4MKCE/hvEg2NBwmk9606	intact-crc:A5CC81D6B3101302|rigid:A10WVZX/MLOnSgQltXoXkAhsDLk	false	-	-	1	1	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"
uniprotkb:P0AA10	uniprotkb:Q9NX20	intact:EBI-543801|uniprotkb:P02410|uniprotkb:Q2M8Y2	intact:EBI-2560190|ensembl:ENSP00000300151.4|uniprotkb:Q9HB70|uniprotkb:Q9BYD0	psi-mi:rl13_ecoli(display_long)|uniprotkb:rplM(gene name)|psi-mi:rplM(display_short)|uniprotkb:50S ribosomal protein L13(gene name synonym)|uniprotkb:JW3200(locus name)|uniprotkb:b3231(locus name)	psi-mi:rm16_human(display_long)|uniprotkb:MRPL16(gene name)|psi-mi:MRPL16(display_short)|uniprotkb:39S ribosomal protein L16, mitochondrial(gene name synonym)|uniprotkb:PNAS-111(orf name)	"psi-mi:""MI:0410""(3D electron microscopy)"	Sharma et al. (2009)	imex:IM-28866|pubmed:19497863	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-26574923|wwpdb:3IY9|emdb:EMD-5113|imex:IM-28866-3	intact-miscore:0.32	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_417698.1|refseq:WP_000847559.1|dip:DIP-47837N|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003729""(mRNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0008270""(zinc ion binding)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0022625""(cytosolic large ribosomal subunit)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0070180""(large ribosomal subunit rRNA binding)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR005823(Ribosomal protein L13, bacterial-type)|interpro:IPR023563|interpro:IPR036899|rcsb pdb:1ML5|rcsb pdb:2J28|rcsb pdb:2RDO|rcsb pdb:3BBX|rcsb pdb:3IY9|rcsb pdb:3J5L|rcsb pdb:3J7Z|rcsb pdb:3J8G|rcsb pdb:3J9Y|rcsb pdb:3J9Z|rcsb pdb:3JA1|rcsb pdb:3JBU|rcsb pdb:3JBV|rcsb pdb:3JCD|rcsb pdb:3JCE|rcsb pdb:3JCJ|rcsb pdb:3JCN|rcsb pdb:4CSU|rcsb pdb:4U1U|rcsb pdb:4U1V|rcsb pdb:4U20|rcsb pdb:4U24|rcsb pdb:4U25|rcsb pdb:4U26|rcsb pdb:4U27|rcsb pdb:4UY8|rcsb pdb:4V47|rcsb pdb:4V48|rcsb pdb:4V4H|rcsb pdb:4V4Q|rcsb pdb:4V4V|rcsb pdb:4V4W|rcsb pdb:4V50|rcsb pdb:4V52|rcsb pdb:4V53|rcsb pdb:4V54|rcsb pdb:4V55|rcsb pdb:4V56|rcsb pdb:4V57|rcsb pdb:4V5B|rcsb pdb:4V5H|rcsb pdb:4V5Y|rcsb pdb:4V64|rcsb pdb:4V65|rcsb pdb:4V66|rcsb pdb:4V69|rcsb pdb:4V6C|rcsb pdb:4V6D|rcsb pdb:4V6E|rcsb pdb:4V6K|rcsb pdb:4V6L|rcsb pdb:4V6M|rcsb pdb:4V6N|rcsb pdb:4V6O|rcsb pdb:4V6P|rcsb pdb:4V6Q|rcsb pdb:4V6R|rcsb pdb:4V6S|rcsb pdb:4V6T|rcsb pdb:4V6V|rcsb pdb:4V6Y|rcsb pdb:4V6Z|rcsb pdb:4V70|rcsb pdb:4V71|rcsb pdb:4V72|rcsb pdb:4V73|rcsb pdb:4V74|rcsb pdb:4V75|rcsb pdb:4V76|rcsb pdb:4V77|rcsb pdb:4V78|rcsb pdb:4V79|rcsb pdb:4V7A|rcsb pdb:4V7B|rcsb pdb:4V7C|rcsb pdb:4V7D|rcsb pdb:4V7I|rcsb pdb:4V7S|rcsb pdb:4V7T|rcsb pdb:4V7U|rcsb pdb:4V7V|rcsb pdb:4V85|rcsb pdb:4V89|rcsb pdb:4V9C|rcsb pdb:4V9D|rcsb pdb:4V9O|rcsb pdb:4V9P|rcsb pdb:4WF1|rcsb pdb:4WOI|rcsb pdb:4WWW|rcsb pdb:4YBB|rcsb pdb:5ADY|rcsb pdb:5AFI|rcsb pdb:5AKA|rcsb pdb:5GAD|rcsb pdb:5GAE|rcsb pdb:5GAF|rcsb pdb:5GAG|rcsb pdb:5GAH|rcsb pdb:5H5U|rcsb pdb:5IQR|rcsb pdb:5IT8|rcsb pdb:5J5B|rcsb pdb:5J7L|rcsb pdb:5J88|rcsb pdb:5J8A|rcsb pdb:5J91|rcsb pdb:5JC9|rcsb pdb:5JTE|rcsb pdb:5JU8|rcsb pdb:5KCR|rcsb pdb:5KCS|rcsb pdb:5KPS|rcsb pdb:5KPV|rcsb pdb:5KPW|rcsb pdb:5KPX|rcsb pdb:5L3P|rcsb pdb:5LZA|rcsb pdb:5LZB|rcsb pdb:5LZC|rcsb pdb:5LZD|rcsb pdb:5LZE|rcsb pdb:5LZF|rcsb pdb:5MDV|rcsb pdb:5MDW|rcsb pdb:5MDY|rcsb pdb:5MDZ|rcsb pdb:5MGP|rcsb pdb:5NCO|rcsb pdb:5NP6|rcsb pdb:5NWY|rcsb pdb:5O2R|rcsb pdb:5U4I|rcsb pdb:5U9F|rcsb pdb:5U9G|rcsb pdb:5UYK|rcsb pdb:5UYL|rcsb pdb:5UYM|rcsb pdb:5UYN|rcsb pdb:5UYP|rcsb pdb:5UYQ|rcsb pdb:5WDT|rcsb pdb:5WE4|rcsb pdb:5WE6|rcsb pdb:5WF0|rcsb pdb:5WFK|rcsb pdb:5WFS|rcsb pdb:6BU8|rcsb pdb:6BY1|rcsb pdb:6C4I|rcsb pdb:6DNC|rcsb pdb:6ENF|rcsb pdb:6ENJ|rcsb pdb:6ENU|rcsb pdb:6GBZ|rcsb pdb:6GC0|rcsb pdb:6GC4|rcsb pdb:6GC6|rcsb pdb:6GC7|rcsb pdb:6GC8|rcsb pdb:6GWT|rcsb pdb:6GXM|rcsb pdb:6GXN|rcsb pdb:6GXO|rcsb pdb:6GXP|rcsb pdb:6H4N|rcsb pdb:6H58|rcsb pdb:6HRM|rcsb pdb:6I0Y|rcsb pdb:6I7V|rcsb pdb:6O9J|rcsb pdb:6O9K|rcsb pdb:6OFX|rcsb pdb:6OG7|rcsb pdb:6OGF|rcsb pdb:6OGG|rcsb pdb:6OGI|rcsb pdb:6OM6|rcsb pdb:6ORE|rcsb pdb:6ORL|rcsb pdb:6OSK|rcsb pdb:6OSQ|rcsb pdb:6OST|rcsb pdb:6OT3|rcsb pdb:6OUO|rcsb pdb:6PC5|rcsb pdb:6PC6|rcsb pdb:6PC7|rcsb pdb:6PC8|rcsb pdb:6PCH|rcsb pdb:6PCQ|rcsb pdb:6PCR|rcsb pdb:6PCS|rcsb pdb:6PCT|rcsb pdb:6PJ6|rcsb pdb:6Q98|rcsb pdb:6Q9A|rcsb pdb:6QDW|rcsb pdb:6QUL|rcsb pdb:6S0K|rcsb pdb:6SZS|rcsb pdb:6TBV|rcsb pdb:6TC3|rcsb pdb:6U48|rcsb pdb:6VU3|rcsb pdb:6VWL|rcsb pdb:6VWM|rcsb pdb:6VWN|rcsb pdb:6VYQ|rcsb pdb:6VYR|rcsb pdb:6VYS|rcsb pdb:6VYT|rcsb pdb:6VYU|rcsb pdb:6VYW|rcsb pdb:6VYX|rcsb pdb:6VYY|rcsb pdb:6VYZ|rcsb pdb:6VZ2|rcsb pdb:6VZ3|rcsb pdb:6VZ5|rcsb pdb:6VZ7|rcsb pdb:6VZJ|rcsb pdb:6WD0|rcsb pdb:6WD1|rcsb pdb:6WD2|rcsb pdb:6WD3|rcsb pdb:6WD4|rcsb pdb:6WD5|rcsb pdb:6WD6|rcsb pdb:6WD7|rcsb pdb:6WD8|rcsb pdb:6WD9|rcsb pdb:6WDA|rcsb pdb:6WDB|rcsb pdb:6WDC|rcsb pdb:6WDD|rcsb pdb:6WDE|rcsb pdb:6WDF|rcsb pdb:6WDG|rcsb pdb:6WDH|rcsb pdb:6WDI|rcsb pdb:6WDJ|rcsb pdb:6WDK|rcsb pdb:6WDL|rcsb pdb:6WDM|rcsb pdb:6WNT|rcsb pdb:6WNV|rcsb pdb:6WNW|rcsb pdb:6WYV|rcsb pdb:6X6T|rcsb pdb:6X7F|rcsb pdb:6X7K|rcsb pdb:6X9Q|rcsb pdb:6XDQ|rcsb pdb:6XDR|rcsb pdb:6XGF|rcsb pdb:6XII|rcsb pdb:6XIJ|rcsb pdb:6XZ7|rcsb pdb:6XZA|rcsb pdb:6XZB|rcsb pdb:6Y69|rcsb pdb:6YS3|rcsb pdb:6YSR|rcsb pdb:6YSS|rcsb pdb:6YST|rcsb pdb:6YSU|rcsb pdb:6ZTJ|rcsb pdb:6ZTL|rcsb pdb:6ZTM|rcsb pdb:6ZTN|rcsb pdb:6ZTO|rcsb pdb:6ZTP|rcsb pdb:6ZU1|rcsb pdb:7ABZ|rcsb pdb:7AC7|rcsb pdb:7ACJ|rcsb pdb:7ACR|rcsb pdb:7B5K|rcsb pdb:7BL2|rcsb pdb:7BL3|rcsb pdb:7BL4|rcsb pdb:7BL5|rcsb pdb:7BL6|rcsb pdb:7BV8|rcsb pdb:7D6Z|rcsb pdb:7D80|rcsb pdb:7JSS|rcsb pdb:7JSW|rcsb pdb:7JSZ|rcsb pdb:7JT1|rcsb pdb:7JT2|rcsb pdb:7JT3|rcsb pdb:7K00|rcsb pdb:7K50|rcsb pdb:7K51|rcsb pdb:7K52|rcsb pdb:7K53|rcsb pdb:7K54|rcsb pdb:7K55|rcsb pdb:7LV0|rcsb pdb:7LVK|rcsb pdb:7M5D|rcsb pdb:7N1P|rcsb pdb:7N2C|rcsb pdb:7N2U|rcsb pdb:7N2V|rcsb pdb:7N30|rcsb pdb:7N31|rcsb pdb:7NBU|rcsb pdb:7NSO|rcsb pdb:7NSP|rcsb pdb:7NSQ|rcsb pdb:7NWT|rcsb pdb:7NWW|rcsb pdb:7O19|rcsb pdb:7O1A|rcsb pdb:7O1C|rcsb pdb:7ODE|rcsb pdb:7OIF|rcsb pdb:7OIG|rcsb pdb:7OII|rcsb pdb:7OIZ|rcsb pdb:7OJ0|rcsb pdb:7OT5|rcsb pdb:7P3K|rcsb pdb:7PJS|rcsb pdb:7PJT|rcsb pdb:7PJV|rcsb pdb:7PJW|rcsb pdb:7PJX|rcsb pdb:7PJY|rcsb pdb:7PJZ|rcsb pdb:7Q4K|rcsb pdb:7QG8|rcsb pdb:7QGH|rcsb pdb:7QGN|rcsb pdb:7QGR|rcsb pdb:7QQ3|rcsb pdb:7S1G|rcsb pdb:7S1H|rcsb pdb:7S1I|rcsb pdb:7S1J|rcsb pdb:7S1K|rcsb pdb:7SA4|rcsb pdb:7SS9|rcsb pdb:7SSD|rcsb pdb:7SSL|rcsb pdb:7SSN|rcsb pdb:7SSO|rcsb pdb:7SSW|rcsb pdb:7ST2|rcsb pdb:7ST6|rcsb pdb:7ST7|rcsb pdb:7TOS|rcsb pdb:7UG7|rcsb pdb:7UPH|rcsb pdb:7Y7C|rcsb pdb:7Y7D|rcsb pdb:7Y7E|rcsb pdb:7Y7F|rcsb pdb:7Y7G|rcsb pdb:7Y7H|rcsb pdb:7YLA|rcsb pdb:7Z20|rcsb pdb:7ZOD|rcsb pdb:7ZP8|rcsb pdb:7ZQ5|rcsb pdb:7ZQ6|rcsb pdb:7ZTA|rcsb pdb:8A3L|rcsb pdb:8AKN|rcsb pdb:8AM9|rcsb pdb:8ANA|rcsb pdb:8AP4|rcsb pdb:8AYE|rcsb pdb:8B0X|rcsb pdb:8B7Y|rcsb pdb:8BF7|rcsb pdb:8BGE|rcsb pdb:8BGH|rcsb pdb:8BH4|rcsb pdb:8BHJ|rcsb pdb:8BHL|rcsb pdb:8BHN|rcsb pdb:8BHP|rcsb pdb:8BIL|rcsb pdb:8BIM|rcsb pdb:8C8X|rcsb pdb:8C8Y|rcsb pdb:8C8Z|rcsb pdb:8C90|rcsb pdb:8C91|rcsb pdb:8C92|rcsb pdb:8C93|rcsb pdb:8C94|rcsb pdb:8C95|rcsb pdb:8C96|rcsb pdb:8C98|rcsb pdb:8C99|rcsb pdb:8CAM|rcsb pdb:8CEU|rcsb pdb:8CGD|rcsb pdb:8CGK|rcsb pdb:8CGV|rcsb pdb:8E30|rcsb pdb:8E32|rcsb pdb:8E33|rcsb pdb:8E35|rcsb pdb:8E36|rcsb pdb:8E3L|rcsb pdb:8E3M|rcsb pdb:8E3O|rcsb pdb:8E41|rcsb pdb:8E42|rcsb pdb:8E43|rcsb pdb:8E44|rcsb pdb:8E45|rcsb pdb:8E46|rcsb pdb:8E47|rcsb pdb:8E48|rcsb pdb:8E49|rcsb pdb:8EIU|rcsb pdb:8EKC|rcsb pdb:8EMM|rcsb pdb:8FIZ|rcsb pdb:8FTO|rcsb pdb:8G2U|rcsb pdb:8G31|rcsb pdb:8G34|rcsb pdb:8G38|rcsb pdb:8G6W|rcsb pdb:8G6X|rcsb pdb:8G6Y|rcsb pdb:8G7P|rcsb pdb:8G7Q|rcsb pdb:8G7R|rcsb pdb:8G7S|rcsb pdb:8HSP|rcsb pdb:8HTZ|rcsb pdb:8HU1|rcsb pdb:8IFB|rcsb pdb:8IFC|rcsb pdb:8J1Z|rcsb pdb:8P16|rcsb pdb:8P17|rcsb pdb:8P18|rcsb pdb:8PEG|rcsb pdb:8PHJ|rcsb pdb:8PKL|rcsb pdb:8PVA|rcsb pdb:8Q4F|rcsb pdb:8QBT|rcsb pdb:8QK7|rcsb pdb:8QOA|rcsb pdb:8R6C|rcsb pdb:8R8M|rcsb pdb:8RPY|rcsb pdb:8RPZ|rcsb pdb:8RQ0|rcsb pdb:8RQ2|rcsb pdb:8SYL|rcsb pdb:8W51|rcsb pdb:9CL9|rcsb pdb:9FBV|panther:PTHR11545(orthology-group)"	"refseq:NP_060310.1|ensembl:ENSG00000166902.5(gene)|ensembl:ENST00000300151.5(transcript)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005762""(mitochondrial large ribosomal subunit)|go:""GO:0019843""(rRNA binding)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR000114(Ribosomal protein L16)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR036920|interpro:IPR047873|mint:Q9NX20|rcsb pdb:3IY9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:7OI6|rcsb pdb:7OI7|rcsb pdb:7OI8|rcsb pdb:7OI9|rcsb pdb:7OIA|rcsb pdb:7OIB|rcsb pdb:7OIC|rcsb pdb:7OID|rcsb pdb:7OIE|rcsb pdb:7PD3|rcsb pdb:7PO4|rcsb pdb:7QH6|rcsb pdb:7QH7|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8K2A|rcsb pdb:8K2B|rcsb pdb:8OIR|rcsb pdb:8OIT|rcsb pdb:8PK0|rcsb pdb:8QSJ|rcsb pdb:8QU1|rcsb pdb:8QU5|rcsb pdb:8XT0|rcsb pdb:8XT1|rcsb pdb:8XT2|rcsb pdb:8XT3|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR12220(orthology-group)"	-	-	-	figure legend:Fig 3, Fig S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/30	2024/11/14	rogid:z77fcwIBr2DCHbFKdrqVqN1bibU83333	rogid:5ngQm8RUtN0SGgxJN2mGtWKhHMU9606	intact-crc:A5CC81D6B3101302|rigid:A10WVZX/MLOnSgQltXoXkAhsDLk	false	-	-	1	1	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"
uniprotkb:P0AA10	uniprotkb:Q9P0M9	intact:EBI-543801|uniprotkb:P02410|uniprotkb:Q2M8Y2	intact:EBI-5325236|uniprotkb:B2RE14|ensembl:ENSP00000225969.4	psi-mi:rl13_ecoli(display_long)|uniprotkb:rplM(gene name)|psi-mi:rplM(display_short)|uniprotkb:50S ribosomal protein L13(gene name synonym)|uniprotkb:JW3200(locus name)|uniprotkb:b3231(locus name)	psi-mi:rm27_human(display_long)|uniprotkb:MRPL27(gene name)|psi-mi:MRPL27(display_short)|uniprotkb:39S ribosomal protein L27, mitochondrial(gene name synonym)|uniprotkb:HSPC250(orf name)	"psi-mi:""MI:0410""(3D electron microscopy)"	Sharma et al. (2009)	imex:IM-28866|pubmed:19497863	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-26574923|wwpdb:3IY9|emdb:EMD-5113|imex:IM-28866-3	intact-miscore:0.32	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_417698.1|refseq:WP_000847559.1|dip:DIP-47837N|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003729""(mRNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0008270""(zinc ion binding)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0022625""(cytosolic large ribosomal subunit)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0070180""(large ribosomal subunit rRNA binding)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR005823(Ribosomal protein L13, bacterial-type)|interpro:IPR023563|interpro:IPR036899|rcsb pdb:1ML5|rcsb pdb:2J28|rcsb pdb:2RDO|rcsb pdb:3BBX|rcsb pdb:3IY9|rcsb pdb:3J5L|rcsb pdb:3J7Z|rcsb pdb:3J8G|rcsb pdb:3J9Y|rcsb pdb:3J9Z|rcsb pdb:3JA1|rcsb pdb:3JBU|rcsb pdb:3JBV|rcsb pdb:3JCD|rcsb pdb:3JCE|rcsb pdb:3JCJ|rcsb pdb:3JCN|rcsb pdb:4CSU|rcsb pdb:4U1U|rcsb pdb:4U1V|rcsb pdb:4U20|rcsb pdb:4U24|rcsb pdb:4U25|rcsb pdb:4U26|rcsb pdb:4U27|rcsb pdb:4UY8|rcsb pdb:4V47|rcsb pdb:4V48|rcsb pdb:4V4H|rcsb pdb:4V4Q|rcsb pdb:4V4V|rcsb pdb:4V4W|rcsb pdb:4V50|rcsb pdb:4V52|rcsb pdb:4V53|rcsb pdb:4V54|rcsb pdb:4V55|rcsb pdb:4V56|rcsb pdb:4V57|rcsb pdb:4V5B|rcsb pdb:4V5H|rcsb pdb:4V5Y|rcsb pdb:4V64|rcsb pdb:4V65|rcsb pdb:4V66|rcsb pdb:4V69|rcsb pdb:4V6C|rcsb pdb:4V6D|rcsb pdb:4V6E|rcsb pdb:4V6K|rcsb pdb:4V6L|rcsb pdb:4V6M|rcsb pdb:4V6N|rcsb pdb:4V6O|rcsb pdb:4V6P|rcsb pdb:4V6Q|rcsb pdb:4V6R|rcsb pdb:4V6S|rcsb pdb:4V6T|rcsb pdb:4V6V|rcsb pdb:4V6Y|rcsb pdb:4V6Z|rcsb pdb:4V70|rcsb pdb:4V71|rcsb pdb:4V72|rcsb pdb:4V73|rcsb pdb:4V74|rcsb pdb:4V75|rcsb pdb:4V76|rcsb pdb:4V77|rcsb pdb:4V78|rcsb pdb:4V79|rcsb pdb:4V7A|rcsb pdb:4V7B|rcsb pdb:4V7C|rcsb pdb:4V7D|rcsb pdb:4V7I|rcsb pdb:4V7S|rcsb pdb:4V7T|rcsb pdb:4V7U|rcsb pdb:4V7V|rcsb pdb:4V85|rcsb pdb:4V89|rcsb pdb:4V9C|rcsb pdb:4V9D|rcsb pdb:4V9O|rcsb pdb:4V9P|rcsb pdb:4WF1|rcsb pdb:4WOI|rcsb pdb:4WWW|rcsb pdb:4YBB|rcsb pdb:5ADY|rcsb pdb:5AFI|rcsb pdb:5AKA|rcsb pdb:5GAD|rcsb pdb:5GAE|rcsb pdb:5GAF|rcsb pdb:5GAG|rcsb pdb:5GAH|rcsb pdb:5H5U|rcsb pdb:5IQR|rcsb pdb:5IT8|rcsb pdb:5J5B|rcsb pdb:5J7L|rcsb pdb:5J88|rcsb pdb:5J8A|rcsb pdb:5J91|rcsb pdb:5JC9|rcsb pdb:5JTE|rcsb pdb:5JU8|rcsb pdb:5KCR|rcsb pdb:5KCS|rcsb pdb:5KPS|rcsb pdb:5KPV|rcsb pdb:5KPW|rcsb pdb:5KPX|rcsb pdb:5L3P|rcsb pdb:5LZA|rcsb pdb:5LZB|rcsb pdb:5LZC|rcsb pdb:5LZD|rcsb pdb:5LZE|rcsb pdb:5LZF|rcsb pdb:5MDV|rcsb pdb:5MDW|rcsb pdb:5MDY|rcsb pdb:5MDZ|rcsb pdb:5MGP|rcsb pdb:5NCO|rcsb pdb:5NP6|rcsb pdb:5NWY|rcsb pdb:5O2R|rcsb pdb:5U4I|rcsb pdb:5U9F|rcsb pdb:5U9G|rcsb pdb:5UYK|rcsb pdb:5UYL|rcsb pdb:5UYM|rcsb pdb:5UYN|rcsb pdb:5UYP|rcsb pdb:5UYQ|rcsb pdb:5WDT|rcsb pdb:5WE4|rcsb pdb:5WE6|rcsb pdb:5WF0|rcsb pdb:5WFK|rcsb pdb:5WFS|rcsb pdb:6BU8|rcsb pdb:6BY1|rcsb pdb:6C4I|rcsb pdb:6DNC|rcsb pdb:6ENF|rcsb pdb:6ENJ|rcsb pdb:6ENU|rcsb pdb:6GBZ|rcsb pdb:6GC0|rcsb pdb:6GC4|rcsb pdb:6GC6|rcsb pdb:6GC7|rcsb pdb:6GC8|rcsb pdb:6GWT|rcsb pdb:6GXM|rcsb pdb:6GXN|rcsb pdb:6GXO|rcsb pdb:6GXP|rcsb pdb:6H4N|rcsb pdb:6H58|rcsb pdb:6HRM|rcsb pdb:6I0Y|rcsb pdb:6I7V|rcsb pdb:6O9J|rcsb pdb:6O9K|rcsb pdb:6OFX|rcsb pdb:6OG7|rcsb pdb:6OGF|rcsb pdb:6OGG|rcsb pdb:6OGI|rcsb pdb:6OM6|rcsb pdb:6ORE|rcsb pdb:6ORL|rcsb pdb:6OSK|rcsb pdb:6OSQ|rcsb pdb:6OST|rcsb pdb:6OT3|rcsb pdb:6OUO|rcsb pdb:6PC5|rcsb pdb:6PC6|rcsb pdb:6PC7|rcsb pdb:6PC8|rcsb pdb:6PCH|rcsb pdb:6PCQ|rcsb pdb:6PCR|rcsb pdb:6PCS|rcsb pdb:6PCT|rcsb pdb:6PJ6|rcsb pdb:6Q98|rcsb pdb:6Q9A|rcsb pdb:6QDW|rcsb pdb:6QUL|rcsb pdb:6S0K|rcsb pdb:6SZS|rcsb pdb:6TBV|rcsb pdb:6TC3|rcsb pdb:6U48|rcsb pdb:6VU3|rcsb pdb:6VWL|rcsb pdb:6VWM|rcsb pdb:6VWN|rcsb pdb:6VYQ|rcsb pdb:6VYR|rcsb pdb:6VYS|rcsb pdb:6VYT|rcsb pdb:6VYU|rcsb pdb:6VYW|rcsb pdb:6VYX|rcsb pdb:6VYY|rcsb pdb:6VYZ|rcsb pdb:6VZ2|rcsb pdb:6VZ3|rcsb pdb:6VZ5|rcsb pdb:6VZ7|rcsb pdb:6VZJ|rcsb pdb:6WD0|rcsb pdb:6WD1|rcsb pdb:6WD2|rcsb pdb:6WD3|rcsb pdb:6WD4|rcsb pdb:6WD5|rcsb pdb:6WD6|rcsb pdb:6WD7|rcsb pdb:6WD8|rcsb pdb:6WD9|rcsb pdb:6WDA|rcsb pdb:6WDB|rcsb pdb:6WDC|rcsb pdb:6WDD|rcsb pdb:6WDE|rcsb pdb:6WDF|rcsb pdb:6WDG|rcsb pdb:6WDH|rcsb pdb:6WDI|rcsb pdb:6WDJ|rcsb pdb:6WDK|rcsb pdb:6WDL|rcsb pdb:6WDM|rcsb pdb:6WNT|rcsb pdb:6WNV|rcsb pdb:6WNW|rcsb pdb:6WYV|rcsb pdb:6X6T|rcsb pdb:6X7F|rcsb pdb:6X7K|rcsb pdb:6X9Q|rcsb pdb:6XDQ|rcsb pdb:6XDR|rcsb pdb:6XGF|rcsb pdb:6XII|rcsb pdb:6XIJ|rcsb pdb:6XZ7|rcsb pdb:6XZA|rcsb pdb:6XZB|rcsb pdb:6Y69|rcsb pdb:6YS3|rcsb pdb:6YSR|rcsb pdb:6YSS|rcsb pdb:6YST|rcsb pdb:6YSU|rcsb pdb:6ZTJ|rcsb pdb:6ZTL|rcsb pdb:6ZTM|rcsb pdb:6ZTN|rcsb pdb:6ZTO|rcsb pdb:6ZTP|rcsb pdb:6ZU1|rcsb pdb:7ABZ|rcsb pdb:7AC7|rcsb pdb:7ACJ|rcsb pdb:7ACR|rcsb pdb:7B5K|rcsb pdb:7BL2|rcsb pdb:7BL3|rcsb pdb:7BL4|rcsb pdb:7BL5|rcsb pdb:7BL6|rcsb pdb:7BV8|rcsb pdb:7D6Z|rcsb pdb:7D80|rcsb pdb:7JSS|rcsb pdb:7JSW|rcsb pdb:7JSZ|rcsb pdb:7JT1|rcsb pdb:7JT2|rcsb pdb:7JT3|rcsb pdb:7K00|rcsb pdb:7K50|rcsb pdb:7K51|rcsb pdb:7K52|rcsb pdb:7K53|rcsb pdb:7K54|rcsb pdb:7K55|rcsb pdb:7LV0|rcsb pdb:7LVK|rcsb pdb:7M5D|rcsb pdb:7N1P|rcsb pdb:7N2C|rcsb pdb:7N2U|rcsb pdb:7N2V|rcsb pdb:7N30|rcsb pdb:7N31|rcsb pdb:7NBU|rcsb pdb:7NSO|rcsb pdb:7NSP|rcsb pdb:7NSQ|rcsb pdb:7NWT|rcsb pdb:7NWW|rcsb pdb:7O19|rcsb pdb:7O1A|rcsb pdb:7O1C|rcsb pdb:7ODE|rcsb pdb:7OIF|rcsb pdb:7OIG|rcsb pdb:7OII|rcsb pdb:7OIZ|rcsb pdb:7OJ0|rcsb pdb:7OT5|rcsb pdb:7P3K|rcsb pdb:7PJS|rcsb pdb:7PJT|rcsb pdb:7PJV|rcsb pdb:7PJW|rcsb pdb:7PJX|rcsb pdb:7PJY|rcsb pdb:7PJZ|rcsb pdb:7Q4K|rcsb pdb:7QG8|rcsb pdb:7QGH|rcsb pdb:7QGN|rcsb pdb:7QGR|rcsb pdb:7QQ3|rcsb pdb:7S1G|rcsb pdb:7S1H|rcsb pdb:7S1I|rcsb pdb:7S1J|rcsb pdb:7S1K|rcsb pdb:7SA4|rcsb pdb:7SS9|rcsb pdb:7SSD|rcsb pdb:7SSL|rcsb pdb:7SSN|rcsb pdb:7SSO|rcsb pdb:7SSW|rcsb pdb:7ST2|rcsb pdb:7ST6|rcsb pdb:7ST7|rcsb pdb:7TOS|rcsb pdb:7UG7|rcsb pdb:7UPH|rcsb pdb:7Y7C|rcsb pdb:7Y7D|rcsb pdb:7Y7E|rcsb pdb:7Y7F|rcsb pdb:7Y7G|rcsb pdb:7Y7H|rcsb pdb:7YLA|rcsb pdb:7Z20|rcsb pdb:7ZOD|rcsb pdb:7ZP8|rcsb pdb:7ZQ5|rcsb pdb:7ZQ6|rcsb pdb:7ZTA|rcsb pdb:8A3L|rcsb pdb:8AKN|rcsb pdb:8AM9|rcsb pdb:8ANA|rcsb pdb:8AP4|rcsb pdb:8AYE|rcsb pdb:8B0X|rcsb pdb:8B7Y|rcsb pdb:8BF7|rcsb pdb:8BGE|rcsb pdb:8BGH|rcsb pdb:8BH4|rcsb pdb:8BHJ|rcsb pdb:8BHL|rcsb pdb:8BHN|rcsb pdb:8BHP|rcsb pdb:8BIL|rcsb pdb:8BIM|rcsb pdb:8C8X|rcsb pdb:8C8Y|rcsb pdb:8C8Z|rcsb pdb:8C90|rcsb pdb:8C91|rcsb pdb:8C92|rcsb pdb:8C93|rcsb pdb:8C94|rcsb pdb:8C95|rcsb pdb:8C96|rcsb pdb:8C98|rcsb pdb:8C99|rcsb pdb:8CAM|rcsb pdb:8CEU|rcsb pdb:8CGD|rcsb pdb:8CGK|rcsb pdb:8CGV|rcsb pdb:8E30|rcsb pdb:8E32|rcsb pdb:8E33|rcsb pdb:8E35|rcsb pdb:8E36|rcsb pdb:8E3L|rcsb pdb:8E3M|rcsb pdb:8E3O|rcsb pdb:8E41|rcsb pdb:8E42|rcsb pdb:8E43|rcsb pdb:8E44|rcsb pdb:8E45|rcsb pdb:8E46|rcsb pdb:8E47|rcsb pdb:8E48|rcsb pdb:8E49|rcsb pdb:8EIU|rcsb pdb:8EKC|rcsb pdb:8EMM|rcsb pdb:8FIZ|rcsb pdb:8FTO|rcsb pdb:8G2U|rcsb pdb:8G31|rcsb pdb:8G34|rcsb pdb:8G38|rcsb pdb:8G6W|rcsb pdb:8G6X|rcsb pdb:8G6Y|rcsb pdb:8G7P|rcsb pdb:8G7Q|rcsb pdb:8G7R|rcsb pdb:8G7S|rcsb pdb:8HSP|rcsb pdb:8HTZ|rcsb pdb:8HU1|rcsb pdb:8IFB|rcsb pdb:8IFC|rcsb pdb:8J1Z|rcsb pdb:8P16|rcsb pdb:8P17|rcsb pdb:8P18|rcsb pdb:8PEG|rcsb pdb:8PHJ|rcsb pdb:8PKL|rcsb pdb:8PVA|rcsb pdb:8Q4F|rcsb pdb:8QBT|rcsb pdb:8QK7|rcsb pdb:8QOA|rcsb pdb:8R6C|rcsb pdb:8R8M|rcsb pdb:8RPY|rcsb pdb:8RPZ|rcsb pdb:8RQ0|rcsb pdb:8RQ2|rcsb pdb:8SYL|rcsb pdb:8W51|rcsb pdb:9CL9|rcsb pdb:9FBV|panther:PTHR11545(orthology-group)"	"refseq:NP_057588.1|rcsb pdb:7O9K|ensembl:ENSG00000108826.16(gene)|ensembl:ENST00000225969.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005762""(mitochondrial large ribosomal subunit)|go:""GO:0006412""(translation)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR001684(Ribosomal protein L27)|mint:Q9P0M9|rcsb pdb:3IY9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:7O9M|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:7OI6|rcsb pdb:7OI7|rcsb pdb:7OI8|rcsb pdb:7OI9|rcsb pdb:7OIA|rcsb pdb:7OIB|rcsb pdb:7OIC|rcsb pdb:7OID|rcsb pdb:7OIE|rcsb pdb:7PD3|rcsb pdb:7PO4|rcsb pdb:7QH6|rcsb pdb:7QH7|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8K2A|rcsb pdb:8K2B|rcsb pdb:8OIR|rcsb pdb:8OIT|rcsb pdb:8PK0|rcsb pdb:8QSJ|rcsb pdb:8QU1|rcsb pdb:8QU5|rcsb pdb:8XT0|rcsb pdb:8XT1|rcsb pdb:8XT2|rcsb pdb:8XT3|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR15893(orthology-group)"	-	-	-	figure legend:Fig 3, Fig S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/30	2024/11/14	rogid:z77fcwIBr2DCHbFKdrqVqN1bibU83333	rogid:Tb7r8GeSkNdNN6aY2mvmTR4MFmc9606	intact-crc:A5CC81D6B3101302|rigid:A10WVZX/MLOnSgQltXoXkAhsDLk	false	-	-	1	1	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"
uniprotkb:P0AA10	uniprotkb:O75394	intact:EBI-543801|uniprotkb:P02410|uniprotkb:Q2M8Y2	intact:EBI-11017723|uniprotkb:Q5FVE3|uniprotkb:Q96Q50|uniprotkb:Q53RZ6|ensembl:ENSP00000296102.3	psi-mi:rl13_ecoli(display_long)|uniprotkb:rplM(gene name)|psi-mi:rplM(display_short)|uniprotkb:50S ribosomal protein L13(gene name synonym)|uniprotkb:JW3200(locus name)|uniprotkb:b3231(locus name)	psi-mi:rm33_human(display_long)|uniprotkb:MRPL33(gene name)|psi-mi:MRPL33(display_short)|uniprotkb:C2orf1(gene name synonym)|uniprotkb:39S ribosomal protein L33, mitochondrial(gene name synonym)	"psi-mi:""MI:0410""(3D electron microscopy)"	Sharma et al. (2009)	imex:IM-28866|pubmed:19497863	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-26574923|wwpdb:3IY9|emdb:EMD-5113|imex:IM-28866-3	intact-miscore:0.32	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_417698.1|refseq:WP_000847559.1|dip:DIP-47837N|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003729""(mRNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0008270""(zinc ion binding)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0022625""(cytosolic large ribosomal subunit)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0070180""(large ribosomal subunit rRNA binding)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR005823(Ribosomal protein L13, bacterial-type)|interpro:IPR023563|interpro:IPR036899|rcsb pdb:1ML5|rcsb pdb:2J28|rcsb pdb:2RDO|rcsb pdb:3BBX|rcsb pdb:3IY9|rcsb pdb:3J5L|rcsb pdb:3J7Z|rcsb pdb:3J8G|rcsb pdb:3J9Y|rcsb pdb:3J9Z|rcsb pdb:3JA1|rcsb pdb:3JBU|rcsb pdb:3JBV|rcsb pdb:3JCD|rcsb pdb:3JCE|rcsb pdb:3JCJ|rcsb pdb:3JCN|rcsb pdb:4CSU|rcsb pdb:4U1U|rcsb pdb:4U1V|rcsb pdb:4U20|rcsb pdb:4U24|rcsb pdb:4U25|rcsb pdb:4U26|rcsb pdb:4U27|rcsb pdb:4UY8|rcsb pdb:4V47|rcsb pdb:4V48|rcsb pdb:4V4H|rcsb pdb:4V4Q|rcsb pdb:4V4V|rcsb pdb:4V4W|rcsb pdb:4V50|rcsb pdb:4V52|rcsb pdb:4V53|rcsb pdb:4V54|rcsb pdb:4V55|rcsb pdb:4V56|rcsb pdb:4V57|rcsb pdb:4V5B|rcsb pdb:4V5H|rcsb pdb:4V5Y|rcsb pdb:4V64|rcsb pdb:4V65|rcsb pdb:4V66|rcsb pdb:4V69|rcsb pdb:4V6C|rcsb pdb:4V6D|rcsb pdb:4V6E|rcsb pdb:4V6K|rcsb pdb:4V6L|rcsb pdb:4V6M|rcsb pdb:4V6N|rcsb pdb:4V6O|rcsb pdb:4V6P|rcsb pdb:4V6Q|rcsb pdb:4V6R|rcsb pdb:4V6S|rcsb pdb:4V6T|rcsb pdb:4V6V|rcsb pdb:4V6Y|rcsb pdb:4V6Z|rcsb pdb:4V70|rcsb pdb:4V71|rcsb pdb:4V72|rcsb pdb:4V73|rcsb pdb:4V74|rcsb pdb:4V75|rcsb pdb:4V76|rcsb pdb:4V77|rcsb pdb:4V78|rcsb pdb:4V79|rcsb pdb:4V7A|rcsb pdb:4V7B|rcsb pdb:4V7C|rcsb pdb:4V7D|rcsb pdb:4V7I|rcsb pdb:4V7S|rcsb pdb:4V7T|rcsb pdb:4V7U|rcsb pdb:4V7V|rcsb pdb:4V85|rcsb pdb:4V89|rcsb pdb:4V9C|rcsb pdb:4V9D|rcsb pdb:4V9O|rcsb pdb:4V9P|rcsb pdb:4WF1|rcsb pdb:4WOI|rcsb pdb:4WWW|rcsb pdb:4YBB|rcsb pdb:5ADY|rcsb pdb:5AFI|rcsb pdb:5AKA|rcsb pdb:5GAD|rcsb pdb:5GAE|rcsb pdb:5GAF|rcsb pdb:5GAG|rcsb pdb:5GAH|rcsb pdb:5H5U|rcsb pdb:5IQR|rcsb pdb:5IT8|rcsb pdb:5J5B|rcsb pdb:5J7L|rcsb pdb:5J88|rcsb pdb:5J8A|rcsb pdb:5J91|rcsb pdb:5JC9|rcsb pdb:5JTE|rcsb pdb:5JU8|rcsb pdb:5KCR|rcsb pdb:5KCS|rcsb pdb:5KPS|rcsb pdb:5KPV|rcsb pdb:5KPW|rcsb pdb:5KPX|rcsb pdb:5L3P|rcsb pdb:5LZA|rcsb pdb:5LZB|rcsb pdb:5LZC|rcsb pdb:5LZD|rcsb pdb:5LZE|rcsb pdb:5LZF|rcsb pdb:5MDV|rcsb pdb:5MDW|rcsb pdb:5MDY|rcsb pdb:5MDZ|rcsb pdb:5MGP|rcsb pdb:5NCO|rcsb pdb:5NP6|rcsb pdb:5NWY|rcsb pdb:5O2R|rcsb pdb:5U4I|rcsb pdb:5U9F|rcsb pdb:5U9G|rcsb pdb:5UYK|rcsb pdb:5UYL|rcsb pdb:5UYM|rcsb pdb:5UYN|rcsb pdb:5UYP|rcsb pdb:5UYQ|rcsb pdb:5WDT|rcsb pdb:5WE4|rcsb pdb:5WE6|rcsb pdb:5WF0|rcsb pdb:5WFK|rcsb pdb:5WFS|rcsb pdb:6BU8|rcsb pdb:6BY1|rcsb pdb:6C4I|rcsb pdb:6DNC|rcsb pdb:6ENF|rcsb pdb:6ENJ|rcsb pdb:6ENU|rcsb pdb:6GBZ|rcsb pdb:6GC0|rcsb pdb:6GC4|rcsb pdb:6GC6|rcsb pdb:6GC7|rcsb pdb:6GC8|rcsb pdb:6GWT|rcsb pdb:6GXM|rcsb pdb:6GXN|rcsb pdb:6GXO|rcsb pdb:6GXP|rcsb pdb:6H4N|rcsb pdb:6H58|rcsb pdb:6HRM|rcsb pdb:6I0Y|rcsb pdb:6I7V|rcsb pdb:6O9J|rcsb pdb:6O9K|rcsb pdb:6OFX|rcsb pdb:6OG7|rcsb pdb:6OGF|rcsb pdb:6OGG|rcsb pdb:6OGI|rcsb pdb:6OM6|rcsb pdb:6ORE|rcsb pdb:6ORL|rcsb pdb:6OSK|rcsb pdb:6OSQ|rcsb pdb:6OST|rcsb pdb:6OT3|rcsb pdb:6OUO|rcsb pdb:6PC5|rcsb pdb:6PC6|rcsb pdb:6PC7|rcsb pdb:6PC8|rcsb pdb:6PCH|rcsb pdb:6PCQ|rcsb pdb:6PCR|rcsb pdb:6PCS|rcsb pdb:6PCT|rcsb pdb:6PJ6|rcsb pdb:6Q98|rcsb pdb:6Q9A|rcsb pdb:6QDW|rcsb pdb:6QUL|rcsb pdb:6S0K|rcsb pdb:6SZS|rcsb pdb:6TBV|rcsb pdb:6TC3|rcsb pdb:6U48|rcsb pdb:6VU3|rcsb pdb:6VWL|rcsb pdb:6VWM|rcsb pdb:6VWN|rcsb pdb:6VYQ|rcsb pdb:6VYR|rcsb pdb:6VYS|rcsb pdb:6VYT|rcsb pdb:6VYU|rcsb pdb:6VYW|rcsb pdb:6VYX|rcsb pdb:6VYY|rcsb pdb:6VYZ|rcsb pdb:6VZ2|rcsb pdb:6VZ3|rcsb pdb:6VZ5|rcsb pdb:6VZ7|rcsb pdb:6VZJ|rcsb pdb:6WD0|rcsb pdb:6WD1|rcsb pdb:6WD2|rcsb pdb:6WD3|rcsb pdb:6WD4|rcsb pdb:6WD5|rcsb pdb:6WD6|rcsb pdb:6WD7|rcsb pdb:6WD8|rcsb pdb:6WD9|rcsb pdb:6WDA|rcsb pdb:6WDB|rcsb pdb:6WDC|rcsb pdb:6WDD|rcsb pdb:6WDE|rcsb pdb:6WDF|rcsb pdb:6WDG|rcsb pdb:6WDH|rcsb pdb:6WDI|rcsb pdb:6WDJ|rcsb pdb:6WDK|rcsb pdb:6WDL|rcsb pdb:6WDM|rcsb pdb:6WNT|rcsb pdb:6WNV|rcsb pdb:6WNW|rcsb pdb:6WYV|rcsb pdb:6X6T|rcsb pdb:6X7F|rcsb pdb:6X7K|rcsb pdb:6X9Q|rcsb pdb:6XDQ|rcsb pdb:6XDR|rcsb pdb:6XGF|rcsb pdb:6XII|rcsb pdb:6XIJ|rcsb pdb:6XZ7|rcsb pdb:6XZA|rcsb pdb:6XZB|rcsb pdb:6Y69|rcsb pdb:6YS3|rcsb pdb:6YSR|rcsb pdb:6YSS|rcsb pdb:6YST|rcsb pdb:6YSU|rcsb pdb:6ZTJ|rcsb pdb:6ZTL|rcsb pdb:6ZTM|rcsb pdb:6ZTN|rcsb pdb:6ZTO|rcsb pdb:6ZTP|rcsb pdb:6ZU1|rcsb pdb:7ABZ|rcsb pdb:7AC7|rcsb pdb:7ACJ|rcsb pdb:7ACR|rcsb pdb:7B5K|rcsb pdb:7BL2|rcsb pdb:7BL3|rcsb pdb:7BL4|rcsb pdb:7BL5|rcsb pdb:7BL6|rcsb pdb:7BV8|rcsb pdb:7D6Z|rcsb pdb:7D80|rcsb pdb:7JSS|rcsb pdb:7JSW|rcsb pdb:7JSZ|rcsb pdb:7JT1|rcsb pdb:7JT2|rcsb pdb:7JT3|rcsb pdb:7K00|rcsb pdb:7K50|rcsb pdb:7K51|rcsb pdb:7K52|rcsb pdb:7K53|rcsb pdb:7K54|rcsb pdb:7K55|rcsb pdb:7LV0|rcsb pdb:7LVK|rcsb pdb:7M5D|rcsb pdb:7N1P|rcsb pdb:7N2C|rcsb pdb:7N2U|rcsb pdb:7N2V|rcsb pdb:7N30|rcsb pdb:7N31|rcsb pdb:7NBU|rcsb pdb:7NSO|rcsb pdb:7NSP|rcsb pdb:7NSQ|rcsb pdb:7NWT|rcsb pdb:7NWW|rcsb pdb:7O19|rcsb pdb:7O1A|rcsb pdb:7O1C|rcsb pdb:7ODE|rcsb pdb:7OIF|rcsb pdb:7OIG|rcsb pdb:7OII|rcsb pdb:7OIZ|rcsb pdb:7OJ0|rcsb pdb:7OT5|rcsb pdb:7P3K|rcsb pdb:7PJS|rcsb pdb:7PJT|rcsb pdb:7PJV|rcsb pdb:7PJW|rcsb pdb:7PJX|rcsb pdb:7PJY|rcsb pdb:7PJZ|rcsb pdb:7Q4K|rcsb pdb:7QG8|rcsb pdb:7QGH|rcsb pdb:7QGN|rcsb pdb:7QGR|rcsb pdb:7QQ3|rcsb pdb:7S1G|rcsb pdb:7S1H|rcsb pdb:7S1I|rcsb pdb:7S1J|rcsb pdb:7S1K|rcsb pdb:7SA4|rcsb pdb:7SS9|rcsb pdb:7SSD|rcsb pdb:7SSL|rcsb pdb:7SSN|rcsb pdb:7SSO|rcsb pdb:7SSW|rcsb pdb:7ST2|rcsb pdb:7ST6|rcsb pdb:7ST7|rcsb pdb:7TOS|rcsb pdb:7UG7|rcsb pdb:7UPH|rcsb pdb:7Y7C|rcsb pdb:7Y7D|rcsb pdb:7Y7E|rcsb pdb:7Y7F|rcsb pdb:7Y7G|rcsb pdb:7Y7H|rcsb pdb:7YLA|rcsb pdb:7Z20|rcsb pdb:7ZOD|rcsb pdb:7ZP8|rcsb pdb:7ZQ5|rcsb pdb:7ZQ6|rcsb pdb:7ZTA|rcsb pdb:8A3L|rcsb pdb:8AKN|rcsb pdb:8AM9|rcsb pdb:8ANA|rcsb pdb:8AP4|rcsb pdb:8AYE|rcsb pdb:8B0X|rcsb pdb:8B7Y|rcsb pdb:8BF7|rcsb pdb:8BGE|rcsb pdb:8BGH|rcsb pdb:8BH4|rcsb pdb:8BHJ|rcsb pdb:8BHL|rcsb pdb:8BHN|rcsb pdb:8BHP|rcsb pdb:8BIL|rcsb pdb:8BIM|rcsb pdb:8C8X|rcsb pdb:8C8Y|rcsb pdb:8C8Z|rcsb pdb:8C90|rcsb pdb:8C91|rcsb pdb:8C92|rcsb pdb:8C93|rcsb pdb:8C94|rcsb pdb:8C95|rcsb pdb:8C96|rcsb pdb:8C98|rcsb pdb:8C99|rcsb pdb:8CAM|rcsb pdb:8CEU|rcsb pdb:8CGD|rcsb pdb:8CGK|rcsb pdb:8CGV|rcsb pdb:8E30|rcsb pdb:8E32|rcsb pdb:8E33|rcsb pdb:8E35|rcsb pdb:8E36|rcsb pdb:8E3L|rcsb pdb:8E3M|rcsb pdb:8E3O|rcsb pdb:8E41|rcsb pdb:8E42|rcsb pdb:8E43|rcsb pdb:8E44|rcsb pdb:8E45|rcsb pdb:8E46|rcsb pdb:8E47|rcsb pdb:8E48|rcsb pdb:8E49|rcsb pdb:8EIU|rcsb pdb:8EKC|rcsb pdb:8EMM|rcsb pdb:8FIZ|rcsb pdb:8FTO|rcsb pdb:8G2U|rcsb pdb:8G31|rcsb pdb:8G34|rcsb pdb:8G38|rcsb pdb:8G6W|rcsb pdb:8G6X|rcsb pdb:8G6Y|rcsb pdb:8G7P|rcsb pdb:8G7Q|rcsb pdb:8G7R|rcsb pdb:8G7S|rcsb pdb:8HSP|rcsb pdb:8HTZ|rcsb pdb:8HU1|rcsb pdb:8IFB|rcsb pdb:8IFC|rcsb pdb:8J1Z|rcsb pdb:8P16|rcsb pdb:8P17|rcsb pdb:8P18|rcsb pdb:8PEG|rcsb pdb:8PHJ|rcsb pdb:8PKL|rcsb pdb:8PVA|rcsb pdb:8Q4F|rcsb pdb:8QBT|rcsb pdb:8QK7|rcsb pdb:8QOA|rcsb pdb:8R6C|rcsb pdb:8R8M|rcsb pdb:8RPY|rcsb pdb:8RPZ|rcsb pdb:8RQ0|rcsb pdb:8RQ2|rcsb pdb:8SYL|rcsb pdb:8W51|rcsb pdb:9CL9|rcsb pdb:9FBV|panther:PTHR11545(orthology-group)"	"refseq:NP_004882.1|refseq:NP_663303.1|ensembl:ENSG00000243147.8(gene)|ensembl:ENST00000296102.8(transcript)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005762""(mitochondrial large ribosomal subunit)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR001705(Ribosomal protein L33)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR038584|interpro:IPR052008|mint:O75394|rcsb pdb:3IY9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:7OI7|rcsb pdb:7OI8|rcsb pdb:7OI9|rcsb pdb:7OIA|rcsb pdb:7OIB|rcsb pdb:7OIC|rcsb pdb:7OID|rcsb pdb:7OIE|rcsb pdb:7PD3|rcsb pdb:7PO4|rcsb pdb:7QH6|rcsb pdb:7QH7|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8K2A|rcsb pdb:8K2B|rcsb pdb:8OIR|rcsb pdb:8OIT|rcsb pdb:8PK0|rcsb pdb:8QSJ|rcsb pdb:8QU1|rcsb pdb:8QU5|rcsb pdb:8XT0|rcsb pdb:8XT1|rcsb pdb:8XT2|rcsb pdb:8XT3|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR47037(orthology-group)"	-	-	-	figure legend:Fig 3, Fig S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/30	2024/11/14	rogid:z77fcwIBr2DCHbFKdrqVqN1bibU83333	rogid:91B+WMCkpqQlgAsAkYEXi6VVyZ89606	intact-crc:A5CC81D6B3101302|rigid:A10WVZX/MLOnSgQltXoXkAhsDLk	false	-	-	1	1	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"
uniprotkb:P60880	uniprotkb:P60601	intact:EBI-524785|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|ensembl:ENSP00000254976.3|ensembl:ENSP00000508541.1|ensembl:ENSP00000508837.1|ensembl:ENSP00000508939.1|ensembl:ENSP00000509287.1|ensembl:ENSP00000509312.1|ensembl:ENSP00000509759.1|ensembl:ENSP00000510109.1|ensembl:ENSP00000510219.1|ensembl:ENSP00000510558.1|ensembl:ENSP00000510663.1|uniprotkb:B2RAU4|uniprotkb:Q53EM2|uniprotkb:Q5U0B5|uniprotkb:D3DW16|uniprotkb:D3DW17	intact:EBI-26578057	psi-mi:snp25_human(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:SNAP25(gene name)|psi-mi:SNAP25(display_short)|uniprotkb:SNAP(gene name synonym)	psi-mi:his5_rhopa(display_long)|uniprotkb:IGP synthase glutaminase subunit(gene name synonym)|uniprotkb:IGP synthase subunit HisH(gene name synonym)|uniprotkb:ImGP synthase subunit HisH(gene name synonym)|uniprotkb:RPA0311(locus name)|uniprotkb:hisH(gene name)|psi-mi:hisH(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Ramos-Miguel et al. (2019)	pubmed:30610939|imex:IM-28601	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:258594(rhopa)|taxid:258594(""Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26578093|imex:IM-28601-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000132639.15(gene)|ensembl:ENST00000254976.7(transcript)|ensembl:ENST00000685131.1(transcript)|ensembl:ENST00000687785.1(transcript)|ensembl:ENST00000689757.1(transcript)|ensembl:ENST00000689858.1(transcript)|ensembl:ENST00000690812.1(transcript)|ensembl:ENST00000691161.1(transcript)|ensembl:ENST00000691353.1(transcript)|ensembl:ENST00000691665.1(transcript)|ensembl:ENST00000692411.1(transcript)|ensembl:ENST00000693325.1(transcript)|go:""GO:0001504""(neurotransmitter uptake)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0005249""(voltage-gated potassium channel activity)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006887""(exocytosis)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007409""(axonogenesis)|go:""GO:0007616""(long-term memory)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0008289""(lipid binding)|go:""GO:0008306""(associative learning)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016079""(synaptic vesicle exocytosis)|go:""GO:0016081""(synaptic vesicle docking)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0016197""(endosomal transport)|go:""GO:0017022""(myosin binding)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030175""(filopodium)|go:""GO:0030426""(growth cone)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044295""(axonal growth cone)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0051963""(regulation of synapse assembly)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0070032""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:""GO:0070033""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:""GO:0070044""(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0097470""(ribbon synapse)|go:""GO:0098888""(extrinsic component of presynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099525""(presynaptic dense core vesicle exocytosis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60880|rcsb pdb:1KIL|rcsb pdb:1XTG|rcsb pdb:2N1T|rcsb pdb:3DDA|rcsb pdb:3DDB|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:3ZUR|rcsb pdb:5W7I|rcsb pdb:5W7J|rcsb pdb:6JLH|rcsb pdb:8BAN|rcsb pdb:8BAV|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250968|reactome:R-HSA-5250971|reactome:R-HSA-5250992|reactome:R-HSA-6798695|reactome:R-HSA-888590|reactome:R-HSA-9662360|refseq:NP_001309831.1|refseq:NP_001309832.1|refseq:NP_001309833.1|refseq:NP_001309834.1|refseq:NP_001309835.1|refseq:NP_001309836.1|refseq:NP_001309837.1|refseq:NP_001309838.1|refseq:NP_001309839.1|refseq:NP_003072.2|refseq:NP_570824.1|refseq:XP_005260865.1|refseq:XP_016883510.1|refseq:XP_016883511.1|dip:DIP-34554N|efo:""Orphanet:98914""|panther:PTHR19305(orthology-group)"	"refseq:WP_011155879.1|interpro:IPR029062|interpro:IPR017926|interpro:IPR010139(Imidazole glycerol phosphate synthase, subunit H)|go:""GO:0000105""(L-histidine biosynthetic process)|go:""GO:0000107""(imidazoleglycerol-phosphate synthase activity)|go:""GO:0004359""(glutaminase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0016829""(lyase activity)|mint:P60601"	-	-	-	figure legend:ST2 ST3|curation depth:imex curation|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions	taxid:9606(human-brain-caudate_nucleus)|taxid:9606(Homo sapiens brain, caudate nuclear region)	-	2020/12/30	2025/03/26	rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs9606	rogid:Lw3hkatIndmrLrWNy2d6W8ngU6M258594	intact-crc:B2DA0C6935729C63|rigid:mveF/eKKR/8+XTujVjV5bTZxTE8	false	-	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:B7UR60	uniprotkb:Q13424	intact:EBI-25435618	intact:EBI-717191|intact:EBI-28985258|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40|ensembl:ENSP00000217381.2	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26377591|imex:IM-28455-21	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"efo:""Orphanet:101016""|dip:DIP-966N|ensembl:ENSG00000101400.6(gene)|ensembl:ENST00000217381.3(transcript)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0003117""(regulation of vasoconstriction by circulating norepinephrine)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006936""(muscle contraction)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016013""(syntrophin complex)|go:""GO:0017080""(sodium channel regulator activity)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042383""(sarcolemma)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0060307""(regulation of ventricular cardiac muscle cell membrane repolarization)|go:""GO:0070161""(anchoring junction)|go:""GO:0086005""(ventricular cardiac muscle cell action potential)|go:""GO:1902083""(negative regulation of peptidyl-cysteine S-nitrosylation)|go:""GO:1902305""(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|interpro:IPR055108|mint:Q13424|refseq:NP_003089.1|panther:PTHR10554(orthology-group)"	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2025/02/25	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	intact-crc:9C874DB4EE22EFDA|rigid:P+G3Aria4ASXYXpH49TridDfhSQ	false	-	binding-associated region:79-300	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B7UR60	uniprotkb:Q9NUP9	intact:EBI-25435618	intact:EBI-1171517|ensembl:ENSP00000278193.2	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26377624|imex:IM-28455-23	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"refseq:NP_060832.1|panther:PTHR14063(orthology-group)|ensembl:ENSG00000148943.12(gene)|ensembl:ENST00000278193.7(transcript)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006887""(exocytosis)|go:""GO:0007269""(neurotransmitter secretion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015031""(protein transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0045202""(synapse)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0097016""(L27 domain binding)|go:""GO:0097025""(MPP7-DLG1-LIN7 complex)|go:""GO:0098793""(presynapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|interpro:IPR051109|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|interpro:IPR001478(PDZ/DHR/GLGF)"	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/14	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606	intact-crc:4303F71CA93326E8|rigid:nIKdSbFKriUtE/Yq4PRiT1L/9vo	false	-	binding-associated region:1-194	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B7UR60	uniprotkb:Q5EBL8	intact:EBI-25435618	intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666.4|ensembl:ENSP00000363578.1|ensembl:ENSP00000512017.1|ensembl:ENSP00000512018.1|ensembl:ENSP00000512019.1	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26377632|imex:IM-28455-1	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509.12(gene)|ensembl:ENST00000239666.9(transcript)|ensembl:ENST00000374454.1(transcript)|ensembl:ENST00000473667.6(transcript)|ensembl:ENST00000486461.2(transcript)|ensembl:ENST00000695560.1(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0046930""(pore complex)|go:""GO:0046931""(pore complex assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051109|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837|panther:PTHR14063(orthology-group)|interpro:IPR001478(PDZ/DHR/GLGF)"	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/14	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606	intact-crc:118BAF58A31A3CF2|rigid:no3JaFTsH48zrfgkdarRkH190Ig	false	-	binding-associated region:1-139	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B7UR60	uniprotkb:Q96L92	intact:EBI-25435618	intact:EBI-2514865|uniprotkb:Q9H3K8|uniprotkb:Q4AEJ5|uniprotkb:Q5VWB0|uniprotkb:Q5VWB2|uniprotkb:Q96D79|uniprotkb:Q5VWB1|uniprotkb:Q32Q36|uniprotkb:Q6IPP6|uniprotkb:Q86UB1|ensembl:ENSP00000400333.2	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:snx27_human(display_long)|uniprotkb:SNX27(gene name)|psi-mi:SNX27(display_short)|uniprotkb:KIAA0488(gene name synonym)|uniprotkb:My014(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26377638|imex:IM-28455-3	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"refseq:NP_001317652.1|refseq:NP_112180.4|ensembl:ENSG00000143376.14(gene)|ensembl:ENST00000458013.7(transcript)|go:""GO:0001770""(establishment of natural killer cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007165""(signal transduction)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098837""(postsynaptic recycling endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001683(Phox-like)|interpro:IPR029071|interpro:IPR036034|interpro:IPR036871|interpro:IPR037827|interpro:IPR037833|interpro:IPR037835|mint:Q96L92|rcsb pdb:4HAS|rcsb pdb:5ZN9|rcsb pdb:6SAK|rcsb pdb:7CT1|rcsb pdb:7E0B|rcsb pdb:7P72|rcsb pdb:7PCB|rcsb pdb:8TTT|rcsb pdb:8TTU|rcsb pdb:8TTV|panther:PTHR12431(orthology-group)|interpro:IPR001478(PDZ/DHR/GLGF)"	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/14	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:UsAQwtTpOo87fFo6fQJNAZxrFe09606	intact-crc:9AE06649F4B28242|rigid:CIyUYldJHdhHRXd6rTNXEK2x85A	false	-	binding-associated region:56-167	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B7UR60	uniprotkb:O95487	intact:EBI-25435618	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175.4|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26377646|imex:IM-28455-25	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802.11(gene)|ensembl:ENST00000265175.5(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008270""(zinc ion binding)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0035909""(aorta morphogenesis)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060463""(lung lobe morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061156""(pulmonary artery morphogenesis)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:0090178""(regulation of establishment of planar polarity involved in neural tube closure)|go:""GO:1901301""(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|interpro:IPR050550|mint:O95487|rcsb pdb:3EH1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-9705671|reactome:R-HSA-983170|panther:PTHR13803(orthology-group)|refseq:NP_001287742.1|refseq:NP_001305014.1|refseq:NP_001305015.1|interpro:IPR001478(PDZ/DHR/GLGF)"	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/06	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	intact-crc:02E39992F7FD7A21|rigid:UKgj27WJYDVLh13UDAp2rsO6fio	false	-	binding-associated region:67-292	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B7UR60	uniprotkb:Q13428	intact:EBI-25435618	intact:EBI-396105|uniprotkb:Q6SC72|uniprotkb:Q7Z5W9|uniprotkb:Q96A52|uniprotkb:Q99408|uniprotkb:Q99860|uniprotkb:A0JLU0|uniprotkb:B4E111|ensembl:ENSP00000367028.4|ensembl:ENSP00000421655.2|intact:EBI-28974716	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:tcof_human(display_long)|uniprotkb:TCOF1(gene name)|psi-mi:TCOF1(display_short)|uniprotkb:Treacher Collins syndrome protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26377654|imex:IM-28455-5	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"panther:PTHR20787(orthology-group)|ensembl:ENSG00000070814.22(gene)|ensembl:ENST00000377797.7(transcript)|ensembl:ENST00000504761.6(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001650""(fibrillar center)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006417""(regulation of translation)|go:""GO:0014029""(neural crest formation)|go:""GO:0014032""(neural crest cell development)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0042790""(nucleolar large rRNA transcription by RNA polymerase I)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0097110""(scaffold protein binding)|interpro:IPR003993(Treacher Collins syndrome, treacle)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR017859|mint:Q13428|refseq:NP_000347.2|refseq:NP_001008657.1|refseq:NP_001128715.1|refseq:NP_001128716.1|refseq:NP_001128717.1|refseq:NP_001182070.1|refseq:XP_005268562.1|efo:""Orphanet:861""|dip:DIP-32953N|interpro:IPR001478(PDZ/DHR/GLGF)"	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2025/03/01	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:eRazgHpn5CwQVFH5hRnA/sVp24M9606	intact-crc:1F88CC8E0FDC197B|rigid:XgON+FSIMEMDf7J15OYZfImFjR4	false	-	binding-associated region:356-513	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B7UR60	uniprotkb:Q13424	intact:EBI-25435618	intact:EBI-717191|intact:EBI-28985258|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40|ensembl:ENSP00000217381.2	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26378057|imex:IM-28455-27	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"efo:""Orphanet:101016""|dip:DIP-966N|ensembl:ENSG00000101400.6(gene)|ensembl:ENST00000217381.3(transcript)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0003117""(regulation of vasoconstriction by circulating norepinephrine)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006936""(muscle contraction)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016013""(syntrophin complex)|go:""GO:0017080""(sodium channel regulator activity)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042383""(sarcolemma)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0060307""(regulation of ventricular cardiac muscle cell membrane repolarization)|go:""GO:0070161""(anchoring junction)|go:""GO:0086005""(ventricular cardiac muscle cell action potential)|go:""GO:1902083""(negative regulation of peptidyl-cysteine S-nitrosylation)|go:""GO:1902305""(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|interpro:IPR055108|mint:Q13424|refseq:NP_003089.1|panther:PTHR10554(orthology-group)"	-	-	-	figure legend:fig.1a, fig. 2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2025/02/25	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	intact-crc:FCF7B554B737847B|rigid:P+G3Aria4ASXYXpH49TridDfhSQ	false	necessary binding region:434-440|mutation disrupting interaction:437-437,440-440	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UR60	uniprotkb:O95487	intact:EBI-25435618	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175.4|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26429143|imex:IM-28455-7	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802.11(gene)|ensembl:ENST00000265175.5(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008270""(zinc ion binding)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0035909""(aorta morphogenesis)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060463""(lung lobe morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061156""(pulmonary artery morphogenesis)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:0090178""(regulation of establishment of planar polarity involved in neural tube closure)|go:""GO:1901301""(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|interpro:IPR050550|mint:O95487|rcsb pdb:3EH1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-9705671|reactome:R-HSA-983170|panther:PTHR13803(orthology-group)|refseq:NP_001287742.1|refseq:NP_001305014.1|refseq:NP_001305015.1"	-	-	-	figure legend:fig.1a, fig. 2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/06	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	intact-crc:2D933713E796C823|rigid:UKgj27WJYDVLh13UDAp2rsO6fio	false	necessary binding region:434-440|mutation disrupting interaction:437-437,440-440	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UR60	uniprotkb:Q13428	intact:EBI-25435618	intact:EBI-396105|uniprotkb:Q6SC72|uniprotkb:Q7Z5W9|uniprotkb:Q96A52|uniprotkb:Q99408|uniprotkb:Q99860|uniprotkb:A0JLU0|uniprotkb:B4E111|ensembl:ENSP00000367028.4|ensembl:ENSP00000421655.2|intact:EBI-28974716	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:tcof_human(display_long)|uniprotkb:TCOF1(gene name)|psi-mi:TCOF1(display_short)|uniprotkb:Treacher Collins syndrome protein(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26429152|imex:IM-28455-29	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"panther:PTHR20787(orthology-group)|ensembl:ENSG00000070814.22(gene)|ensembl:ENST00000377797.7(transcript)|ensembl:ENST00000504761.6(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001650""(fibrillar center)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006417""(regulation of translation)|go:""GO:0014029""(neural crest formation)|go:""GO:0014032""(neural crest cell development)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0042790""(nucleolar large rRNA transcription by RNA polymerase I)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0097110""(scaffold protein binding)|interpro:IPR003993(Treacher Collins syndrome, treacle)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR017859|mint:Q13428|refseq:NP_000347.2|refseq:NP_001008657.1|refseq:NP_001128715.1|refseq:NP_001128716.1|refseq:NP_001128717.1|refseq:NP_001182070.1|refseq:XP_005268562.1|efo:""Orphanet:861""|dip:DIP-32953N"	-	-	-	figure legend:fig.1a, fig. 2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2025/03/01	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:eRazgHpn5CwQVFH5hRnA/sVp24M9606	intact-crc:7D42D60687CF0807|rigid:XgON+FSIMEMDf7J15OYZfImFjR4	false	mutation with no effect:437-437,440-440	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5EBL8	uniprotkb:B7UR60	intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666.4|ensembl:ENSP00000363578.1|ensembl:ENSP00000512017.1|ensembl:ENSP00000512018.1|ensembl:ENSP00000512019.1	intact:EBI-25435618	psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26429175|imex:IM-28455-31	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509.12(gene)|ensembl:ENST00000239666.9(transcript)|ensembl:ENST00000374454.1(transcript)|ensembl:ENST00000473667.6(transcript)|ensembl:ENST00000486461.2(transcript)|ensembl:ENST00000695560.1(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0046930""(pore complex)|go:""GO:0046931""(pore complex assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051109|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837|panther:PTHR14063(orthology-group)"	mint:B7UR60|refseq:WP_001025663.1	-	-	-	figure legend:fig.1a, fig. 2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/14	rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	intact-crc:765079D7BF85009D|rigid:no3JaFTsH48zrfgkdarRkH190Ig	false	-	mutation disrupting interaction:437-437,440-440|necessary binding region:434-440	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NUP9	uniprotkb:B7UR60	intact:EBI-1171517|ensembl:ENSP00000278193.2	intact:EBI-25435618	psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26429184|imex:IM-28455-9	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060832.1|panther:PTHR14063(orthology-group)|ensembl:ENSG00000148943.12(gene)|ensembl:ENST00000278193.7(transcript)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006887""(exocytosis)|go:""GO:0007269""(neurotransmitter secretion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015031""(protein transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0045202""(synapse)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0097016""(L27 domain binding)|go:""GO:0097025""(MPP7-DLG1-LIN7 complex)|go:""GO:0098793""(presynapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|interpro:IPR051109|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736"	mint:B7UR60|refseq:WP_001025663.1	-	-	-	figure legend:fig.1a, fig. 2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/14	rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	intact-crc:0B32A5AD5B59AF54|rigid:nIKdSbFKriUtE/Yq4PRiT1L/9vo	false	-	mutation disrupting interaction:437-437,440-440|necessary binding region:434-440	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96L92	uniprotkb:B7UR60	intact:EBI-2514865|uniprotkb:Q9H3K8|uniprotkb:Q4AEJ5|uniprotkb:Q5VWB0|uniprotkb:Q5VWB2|uniprotkb:Q96D79|uniprotkb:Q5VWB1|uniprotkb:Q32Q36|uniprotkb:Q6IPP6|uniprotkb:Q86UB1|ensembl:ENSP00000400333.2	intact:EBI-25435618	psi-mi:snx27_human(display_long)|uniprotkb:SNX27(gene name)|psi-mi:SNX27(display_short)|uniprotkb:KIAA0488(gene name synonym)|uniprotkb:My014(orf name)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26429193|imex:IM-28455-11	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001317652.1|refseq:NP_112180.4|ensembl:ENSG00000143376.14(gene)|ensembl:ENST00000458013.7(transcript)|go:""GO:0001770""(establishment of natural killer cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007165""(signal transduction)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098837""(postsynaptic recycling endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001683(Phox-like)|interpro:IPR029071|interpro:IPR036034|interpro:IPR036871|interpro:IPR037827|interpro:IPR037833|interpro:IPR037835|mint:Q96L92|rcsb pdb:4HAS|rcsb pdb:5ZN9|rcsb pdb:6SAK|rcsb pdb:7CT1|rcsb pdb:7E0B|rcsb pdb:7P72|rcsb pdb:7PCB|rcsb pdb:8TTT|rcsb pdb:8TTU|rcsb pdb:8TTV|panther:PTHR12431(orthology-group)"	mint:B7UR60|refseq:WP_001025663.1	-	-	-	figure legend:fig.1a, fig. 2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/14	rogid:UsAQwtTpOo87fFo6fQJNAZxrFe09606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	intact-crc:02CADD4F32C63C88|rigid:CIyUYldJHdhHRXd6rTNXEK2x85A	false	-	mutation with no effect:437-437,440-440|necessary binding region:434-440	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NUP9	uniprotkb:D2TJZ4	intact:EBI-1171517|ensembl:ENSP00000278193.2	intact:EBI-13953726	psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym)	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26430129|imex:IM-28455-48	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060832.1|panther:PTHR14063(orthology-group)|ensembl:ENSG00000148943.12(gene)|ensembl:ENST00000278193.7(transcript)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006887""(exocytosis)|go:""GO:0007269""(neurotransmitter secretion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015031""(protein transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0045202""(synapse)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0097016""(L27 domain binding)|go:""GO:0097025""(MPP7-DLG1-LIN7 complex)|go:""GO:0098793""(presynapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|interpro:IPR051109|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736"	refseq:WP_012904700.1|mint:D2TJZ4	-	-	-	figure legend:fig.6a|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/14	rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	intact-crc:81B2466544072D87|rigid:0sn2aKxYCjx2Tik9mOmdbj/Cj/k	false	-	necessary binding region:424-430	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96L92	uniprotkb:D2TJZ4	intact:EBI-2514865|uniprotkb:Q9H3K8|uniprotkb:Q4AEJ5|uniprotkb:Q5VWB0|uniprotkb:Q5VWB2|uniprotkb:Q96D79|uniprotkb:Q5VWB1|uniprotkb:Q32Q36|uniprotkb:Q6IPP6|uniprotkb:Q86UB1|ensembl:ENSP00000400333.2	intact:EBI-13953726	psi-mi:snx27_human(display_long)|uniprotkb:SNX27(gene name)|psi-mi:SNX27(display_short)|uniprotkb:KIAA0488(gene name synonym)|uniprotkb:My014(orf name)	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26430138|imex:IM-28455-50	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001317652.1|refseq:NP_112180.4|ensembl:ENSG00000143376.14(gene)|ensembl:ENST00000458013.7(transcript)|go:""GO:0001770""(establishment of natural killer cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007165""(signal transduction)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098837""(postsynaptic recycling endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001683(Phox-like)|interpro:IPR029071|interpro:IPR036034|interpro:IPR036871|interpro:IPR037827|interpro:IPR037833|interpro:IPR037835|mint:Q96L92|rcsb pdb:4HAS|rcsb pdb:5ZN9|rcsb pdb:6SAK|rcsb pdb:7CT1|rcsb pdb:7E0B|rcsb pdb:7P72|rcsb pdb:7PCB|rcsb pdb:8TTT|rcsb pdb:8TTU|rcsb pdb:8TTV|panther:PTHR12431(orthology-group)"	refseq:WP_012904700.1|mint:D2TJZ4	-	-	-	figure legend:fig.6a|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/14	rogid:UsAQwtTpOo87fFo6fQJNAZxrFe09606	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	intact-crc:081413C838916DE0|rigid:04LK6xQlkcfp7L2SyKb6qZSeP1Q	false	-	necessary binding region:424-430	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5EBL8	uniprotkb:D2TJZ4	intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666.4|ensembl:ENSP00000363578.1|ensembl:ENSP00000512017.1|ensembl:ENSP00000512018.1|ensembl:ENSP00000512019.1	intact:EBI-13953726	psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name)	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26430144|imex:IM-28455-52	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509.12(gene)|ensembl:ENST00000239666.9(transcript)|ensembl:ENST00000374454.1(transcript)|ensembl:ENST00000473667.6(transcript)|ensembl:ENST00000486461.2(transcript)|ensembl:ENST00000695560.1(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0046930""(pore complex)|go:""GO:0046931""(pore complex assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051109|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837|panther:PTHR14063(orthology-group)"	refseq:WP_012904700.1|mint:D2TJZ4	-	-	-	figure legend:fig.6a|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/14	rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	intact-crc:429D31D0A059517B|rigid:X9k2a7eiIQi//1tFNusoNVrL7IA	false	-	necessary binding region:424-430	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13424	uniprotkb:D2TJZ4	intact:EBI-717191|intact:EBI-28985258|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40|ensembl:ENSP00000217381.2	intact:EBI-13953726	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26430150|imex:IM-28455-54	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:101016""|dip:DIP-966N|ensembl:ENSG00000101400.6(gene)|ensembl:ENST00000217381.3(transcript)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0003117""(regulation of vasoconstriction by circulating norepinephrine)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006936""(muscle contraction)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016013""(syntrophin complex)|go:""GO:0017080""(sodium channel regulator activity)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042383""(sarcolemma)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0060307""(regulation of ventricular cardiac muscle cell membrane repolarization)|go:""GO:0070161""(anchoring junction)|go:""GO:0086005""(ventricular cardiac muscle cell action potential)|go:""GO:1902083""(negative regulation of peptidyl-cysteine S-nitrosylation)|go:""GO:1902305""(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|interpro:IPR055108|mint:Q13424|refseq:NP_003089.1|panther:PTHR10554(orthology-group)"	refseq:WP_012904700.1|mint:D2TJZ4	-	-	-	figure legend:fig.6a|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2025/02/25	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	intact-crc:E2A8F007AEEE3DB4|rigid:SXbyTkqw8yWETa96RTRhm8oFKd0	false	-	necessary binding region:424-430	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95487	uniprotkb:D2TJZ4	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175.4|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	intact:EBI-13953726	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26430156|imex:IM-28455-62	intact-miscore:0.55	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802.11(gene)|ensembl:ENST00000265175.5(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008270""(zinc ion binding)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0035909""(aorta morphogenesis)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060463""(lung lobe morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061156""(pulmonary artery morphogenesis)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:0090178""(regulation of establishment of planar polarity involved in neural tube closure)|go:""GO:1901301""(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|interpro:IPR050550|mint:O95487|rcsb pdb:3EH1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-9705671|reactome:R-HSA-983170|panther:PTHR13803(orthology-group)|refseq:NP_001287742.1|refseq:NP_001305014.1|refseq:NP_001305015.1"	refseq:WP_012904700.1|mint:D2TJZ4	-	-	-	figure legend:fig.6a|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2024/11/06	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	intact-crc:AD19D76F200C0C10|rigid:kOtDZ4w6f78PZmD68E2rIhIZ1No	false	-	necessary binding region:424-430	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13428	uniprotkb:D2TJZ4	intact:EBI-396105|uniprotkb:Q6SC72|uniprotkb:Q7Z5W9|uniprotkb:Q96A52|uniprotkb:Q99408|uniprotkb:Q99860|uniprotkb:A0JLU0|uniprotkb:B4E111|ensembl:ENSP00000367028.4|ensembl:ENSP00000421655.2|intact:EBI-28974716	intact:EBI-13953726	psi-mi:tcof_human(display_long)|uniprotkb:TCOF1(gene name)|psi-mi:TCOF1(display_short)|uniprotkb:Treacher Collins syndrome protein(gene name synonym)	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:nleA(gene name synonym)|uniprotkb:ROD_03401(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910(""Citrobacter rodentium (strain ICC168)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26430162|imex:IM-28455-56	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR20787(orthology-group)|ensembl:ENSG00000070814.22(gene)|ensembl:ENST00000377797.7(transcript)|ensembl:ENST00000504761.6(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001650""(fibrillar center)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006417""(regulation of translation)|go:""GO:0014029""(neural crest formation)|go:""GO:0014032""(neural crest cell development)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0042790""(nucleolar large rRNA transcription by RNA polymerase I)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0097110""(scaffold protein binding)|interpro:IPR003993(Treacher Collins syndrome, treacle)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR017859|mint:Q13428|refseq:NP_000347.2|refseq:NP_001008657.1|refseq:NP_001128715.1|refseq:NP_001128716.1|refseq:NP_001128717.1|refseq:NP_001182070.1|refseq:XP_005268562.1|efo:""Orphanet:861""|dip:DIP-32953N"	refseq:WP_012904700.1|mint:D2TJZ4	-	-	-	figure legend:fig.6a|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/13	2025/03/01	rogid:eRazgHpn5CwQVFH5hRnA/sVp24M9606	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	intact-crc:2863199156A03372|rigid:OGY5ycjb/8608zeSwL+7HQGXj0Y	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UR60	uniprotkb:Q86UL8	intact:EBI-25435618	intact:EBI-311035|uniprotkb:O60434|uniprotkb:O60510|uniprotkb:Q86UI7|uniprotkb:Q9NP44|uniprotkb:Q9UDQ5|uniprotkb:Q9UDU1|uniprotkb:A4D1C1|uniprotkb:A7E2C3|intact:EBI-28973920|ensembl:ENSP00000346151.4	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:magi2_human(display_long)|uniprotkb:MAGI2(gene name)|psi-mi:MAGI2(display_short)|uniprotkb:KIAA0705(gene name synonym)|uniprotkb:ACVRINP1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein A(gene name synonym)|uniprotkb:AIP1(gene name synonym)	"psi-mi:""MI:0089""(protein array)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26429242|imex:IM-28455-33	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"efo:""Orphanet:656""|ensembl:ENSG00000187391.23(gene)|ensembl:ENST00000354212.9(transcript)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005770""(late endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007165""(signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0031697""(beta-1 adrenergic receptor binding)|go:""GO:0032926""(negative regulation of activin receptor signaling pathway)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036057""(slit diaphragm)|go:""GO:0038180""(nerve growth factor signaling pathway)|go:""GO:0043113""(receptor clustering)|go:""GO:0045202""(synapse)|go:""GO:0046332""(SMAD binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0070699""(type II activin receptor binding)|go:""GO:0072015""(podocyte development)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097546""(ciliary base)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR036020|interpro:IPR036034|mint:Q86UL8|rcsb pdb:1UEP|rcsb pdb:1UEQ|rcsb pdb:1UEW|rcsb pdb:1UJV|rcsb pdb:1WFV|reactome:R-HSA-373753|refseq:NP_001288057.1|refseq:NP_036433.2|panther:PTHR10316(orthology-group)"	-	-	-	figure legend:fig. 1b,1c table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2024/11/14	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:/uTMSMqB1wrlyHj2P9OVVBCpWcY9606	intact-crc:94A24F7D88141E9D|rigid:Efgpnx/x/qL8cfcrLXi9Afgr4y8	false	binding-associated region:391-440|glutathione s tranferase tag:?-?	his tag:?-?|binding-associated region:599-743	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:B7UR60	uniprotkb:Q5TCQ9	intact:EBI-25435618	intact:EBI-310506|uniprotkb:Q5TCR0|uniprotkb:Q9H2V6|uniprotkb:Q5TCQ8|uniprotkb:Q9H5Y8|uniprotkb:Q9HBC4|intact:EBI-2512710|intact:EBI-991068|uniprotkb:Q9HCD8|uniprotkb:A0A024R0E9|uniprotkb:A0A024R0H3|ensembl:ENSP00000304604.9	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:magi3_human(display_long)|uniprotkb:MAGI3(gene name)|psi-mi:MAGI3(display_short)|uniprotkb:KIAA1634(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 3(gene name synonym)	"psi-mi:""MI:0089""(protein array)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26429833|imex:IM-28455-13	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"refseq:NP_001136254.1|refseq:NP_690864.2|refseq:XP_005270794.1|ensembl:ENSG00000081026.19(gene)|ensembl:ENST00000307546.14(transcript)|go:""GO:0004385""(guanylate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0030054""(cell junction)|go:""GO:0035556""(intracellular signal transduction)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR036020|interpro:IPR036034|mint:Q5TCQ9|rcsb pdb:3SOE|panther:PTHR10316(orthology-group)"	-	-	-	figure legend:fig. 1b,1c table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2024/11/14	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:muK+zH3ww4Ve8aJ74iU2be8hRa09606	intact-crc:7A89556891574AEC|rigid:gql4iS+HpNlfXC/jjgafV5k9FDY	false	binding-associated region:391-440|glutathione s tranferase tag:?-?	binding-associated region:429-579|his tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:B7UR60	uniprotkb:Q15599	intact:EBI-25435618	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	"psi-mi:""MI:0089""(protein array)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26429856|imex:IM-28455-37	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	-	-	-	figure legend:fig. 1b,1c table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2024/11/14	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	intact-crc:C7FB1042A2BB763A|rigid:uta98I2Rt9s9h2ckdisEtP3ay4M	false	binding-associated region:391-440|glutathione s tranferase tag:?-?	binding-associated region:149-337|his tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:B7UR60	uniprotkb:Q13425	intact:EBI-25435618	intact:EBI-80411|uniprotkb:Q9BY09|ensembl:ENSP00000338191.4	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	"psi-mi:""MI:0089""(protein array)"	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26429985|imex:IM-28455-60	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B7UR60|refseq:WP_001025663.1	"refseq:NP_006741.1|panther:PTHR10554(orthology-group)|ensembl:ENSG00000168807.17(gene)|ensembl:ENST00000336278.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016020""(membrane)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045202""(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|interpro:IPR055108|mint:Q13425|rcsb pdb:2VRF"	-	-	-	figure legend:fig. 1b,1c table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2024/11/14	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	intact-crc:2F1BB8C83FC62DCC|rigid:5tP+GQIYpBLxyqkERQl+OWKrV2A	false	binding-associated region:391-440|glutathione s tranferase tag:?-?	binding-associated region:111-265|his tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:P0A2N1	uniprotkb:Q13164	intact:EBI-26434604|uniprotkb:P21456	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|ensembl:ENSP00000311005.5|ensembl:ENSP00000378966.4|ensembl:ENSP00000378968.3|intact:EBI-28979986	psi-mi:spvc_salen(display_long)|uniprotkb:spvC(gene name)|psi-mi:spvC(display_short)|uniprotkb:mkaD(gene name synonym)|uniprotkb:vsdD(gene name synonym)|uniprotkb:Secreted effector protein SpvC(gene name synonym)|uniprotkb:27.5 kDa virulence protein(gene name synonym)	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Zhu et al. (2007)	imex:IM-28467|pubmed:18060821	taxid:149539(Salmonella enteritidis)|taxid:149539(Salmonella enteritidis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26434617|imex:IM-28467-1	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|refseq:WP_001122242.1|interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|interpro:IPR038498|mint:P0A2N1"	"refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|refseq:XP_011522259.1|ensembl:ENSG00000166484.20(gene)|ensembl:ENST00000308406.9(transcript)|ensembl:ENST00000395602.8(transcript)|ensembl:ENST00000395604.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0016605""(PML body)|go:""GO:0030154""(cell differentiation)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0034115""(negative regulation of heterotypic cell-cell adhesion)|go:""GO:0034392""(negative regulation of smooth muscle cell apoptotic process)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071499""(cellular response to laminar fluid shear stress)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|rcsb pdb:7PUS|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|panther:PTHR24055(orthology-group)|ensembl:ENST00000299612.11|ensembl:ENSP00000299612.7|ensembl:ENSP00000311005.5|ensembl:ENSP00000378966.4|ensembl:ENSP00000378968.3"	pdbe:2q8y	-	-	figure legend:table 1 fig.2 suppl. fig 1A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2024/11/14	rogid:MezetuISvipnkk4GUAaruDCjolg149539	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	intact-crc:9CEC31DF67A69F6F|rigid:QE88anCvC0q/XCN3DjfpJnIaSSc	false	mutation with no effect:136-136	binding-associated region:215-223|O-phospho-L-threonine:219-219|O4'-phospho-L-tyrosine:221-221	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8VSP9	uniprotkb:P28482	intact:EBI-6506625|uniprotkb:Q2ET10|uniprotkb:Q2ET14|uniprotkb:Q6XW10|uniprotkb:Q7BEG0|uniprotkb:Q99Q87	intact:EBI-959949|uniprotkb:A8CZ64|ensembl:ENSP00000215832.7|ensembl:ENSP00000381803.3	psi-mi:ospf_shifl(display_long)|uniprotkb:ospF(gene name)|psi-mi:ospF(display_short)|uniprotkb:mkaD(gene name synonym)|uniprotkb:Effector protein OspF(gene name synonym)|uniprotkb:pWR501_0013(orf name)|uniprotkb:SFLP011(orf name)|uniprotkb:CP0010(locus name)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Zhu et al. (2007)	imex:IM-28467|pubmed:18060821	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0414""(enzymatic reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435196|imex:IM-28467-21	intact-miscore:0.67	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|refseq:NP_858143.1|refseq:YP_006960239.1|refseq:WP_001121867.1|interpro:IPR038498|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|rcsb pdb:3I0U|refseq:WP_010921598.1|mint:Q8VSP9"	"efo:""Orphanet:261330""|dip:DIP-519N|ensembl:ENSG00000100030.15(gene)|ensembl:ENST00000215832.11(transcript)|ensembl:ENST00000398822.7(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007611""(learning or memory)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0014044""(Schwann cell development)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019858""(cytosine metabolic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030641""(regulation of cellular pH)|go:""GO:0030878""(thyroid gland development)|go:""GO:0031143""(pseudopodium)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042473""(outer ear morphogenesis)|go:""GO:0042552""(myelination)|go:""GO:0042802""(identical protein binding)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0043401""(steroid hormone receptor signaling pathway)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060324""(face development)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0060440""(trachea formation)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0061308""(cardiac neural crest cell development involved in heart development)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070849""(response to epidermal growth factor)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:P28482|rcsb pdb:1PME|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|rcsb pdb:7AUV|rcsb pdb:7E73|rcsb pdb:7E75|rcsb pdb:7NQQ|rcsb pdb:7NQW|rcsb pdb:7NR3|rcsb pdb:7NR5|rcsb pdb:7NR8|rcsb pdb:7NR9|rcsb pdb:7OPM|rcsb pdb:7W5O|rcsb pdb:7X4U|rcsb pdb:7XC1|rcsb pdb:8AO2|rcsb pdb:8AO3|rcsb pdb:8AO4|rcsb pdb:8AO5|rcsb pdb:8AO6|rcsb pdb:8AO7|rcsb pdb:8AO8|rcsb pdb:8AO9|rcsb pdb:8AOA|rcsb pdb:8AOB|rcsb pdb:8AOC|rcsb pdb:8AOD|rcsb pdb:8AOE|rcsb pdb:8AOF|rcsb pdb:8AOG|rcsb pdb:8AOH|rcsb pdb:8AOI|rcsb pdb:8AOJ|rcsb pdb:8PSR|rcsb pdb:8PST|rcsb pdb:8PSW|rcsb pdb:8PSY|rcsb pdb:8PT0|rcsb pdb:8PT1|rcsb pdb:8PT3|rcsb pdb:8PT5|rcsb pdb:8U8J|rcsb pdb:8U8K|rcsb pdb:8ZJV|reactome:R-HSA-111995|reactome:R-HSA-112409|reactome:R-HSA-112411|reactome:R-HSA-1181150|reactome:R-HSA-1295596|reactome:R-HSA-1502540|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-877300|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-9725371|reactome:R-HSA-9732724|reactome:R-HSA-9768919|reactome:R-HSA-982772|reactome:R-HSA-9842640|reactome:R-HSA-9856649|refseq:NP_002736.3|refseq:NP_620407.1|panther:PTHR24055(orthology-group)"	-	-	-	"figure legend:fig.1 a,b,c|comment:""\""As shown in Figure 1B, a mass loss of 98 dalton from the Erk2 phosphopeptide was observed as a result of OspF treatment, and an additional mass of 77 dalton was regained after subsequent incubation with cysteamine. Results of tandem mass spectrometry analysis indicate that the 77 dalton mass increase occurred on the “threonine” residue (Figure 1C), consistent with the hypothesized addition reaction of the unsaturated Cα = Cβ bond with cysteamine\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2025/02/26	rogid:mSCbX2cDlV97OQC/v4kEJtqiOIU623	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	intact-crc:4C314EA702F00ADF|rigid:cUYenOUdAYrOkg10xnBDJQ2dcd8	false	-	binding-associated region:179-191|modified L-threonine residue:185-185|O4'-phospho-L-tyrosine:187-187	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q8VSP9	uniprotkb:P28482	intact:EBI-6506625|uniprotkb:Q2ET10|uniprotkb:Q2ET14|uniprotkb:Q6XW10|uniprotkb:Q7BEG0|uniprotkb:Q99Q87	intact:EBI-959949|uniprotkb:A8CZ64|ensembl:ENSP00000215832.7|ensembl:ENSP00000381803.3	psi-mi:ospf_shifl(display_long)|uniprotkb:ospF(gene name)|psi-mi:ospF(display_short)|uniprotkb:mkaD(gene name synonym)|uniprotkb:Effector protein OspF(gene name synonym)|uniprotkb:pWR501_0013(orf name)|uniprotkb:SFLP011(orf name)|uniprotkb:CP0010(locus name)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Zhu et al. (2007)	imex:IM-28467|pubmed:18060821	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435224|imex:IM-28467-3	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|refseq:NP_858143.1|refseq:YP_006960239.1|refseq:WP_001121867.1|interpro:IPR038498|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|rcsb pdb:3I0U|refseq:WP_010921598.1|mint:Q8VSP9"	"efo:""Orphanet:261330""|dip:DIP-519N|ensembl:ENSG00000100030.15(gene)|ensembl:ENST00000215832.11(transcript)|ensembl:ENST00000398822.7(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007611""(learning or memory)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0014044""(Schwann cell development)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019858""(cytosine metabolic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030641""(regulation of cellular pH)|go:""GO:0030878""(thyroid gland development)|go:""GO:0031143""(pseudopodium)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042473""(outer ear morphogenesis)|go:""GO:0042552""(myelination)|go:""GO:0042802""(identical protein binding)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0043401""(steroid hormone receptor signaling pathway)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060324""(face development)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0060440""(trachea formation)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0061308""(cardiac neural crest cell development involved in heart development)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070849""(response to epidermal growth factor)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:P28482|rcsb pdb:1PME|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|rcsb pdb:7AUV|rcsb pdb:7E73|rcsb pdb:7E75|rcsb pdb:7NQQ|rcsb pdb:7NQW|rcsb pdb:7NR3|rcsb pdb:7NR5|rcsb pdb:7NR8|rcsb pdb:7NR9|rcsb pdb:7OPM|rcsb pdb:7W5O|rcsb pdb:7X4U|rcsb pdb:7XC1|rcsb pdb:8AO2|rcsb pdb:8AO3|rcsb pdb:8AO4|rcsb pdb:8AO5|rcsb pdb:8AO6|rcsb pdb:8AO7|rcsb pdb:8AO8|rcsb pdb:8AO9|rcsb pdb:8AOA|rcsb pdb:8AOB|rcsb pdb:8AOC|rcsb pdb:8AOD|rcsb pdb:8AOE|rcsb pdb:8AOF|rcsb pdb:8AOG|rcsb pdb:8AOH|rcsb pdb:8AOI|rcsb pdb:8AOJ|rcsb pdb:8PSR|rcsb pdb:8PST|rcsb pdb:8PSW|rcsb pdb:8PSY|rcsb pdb:8PT0|rcsb pdb:8PT1|rcsb pdb:8PT3|rcsb pdb:8PT5|rcsb pdb:8U8J|rcsb pdb:8U8K|rcsb pdb:8ZJV|reactome:R-HSA-111995|reactome:R-HSA-112409|reactome:R-HSA-112411|reactome:R-HSA-1181150|reactome:R-HSA-1295596|reactome:R-HSA-1502540|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-877300|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-9725371|reactome:R-HSA-9732724|reactome:R-HSA-9768919|reactome:R-HSA-982772|reactome:R-HSA-9842640|reactome:R-HSA-9856649|refseq:NP_002736.3|refseq:NP_620407.1|panther:PTHR24055(orthology-group)"	-	-	-	figure legend:fig. 3b,d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/13	2025/02/26	rogid:mSCbX2cDlV97OQC/v4kEJtqiOIU623	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	intact-crc:F13DEB6167D6CAFD|rigid:cUYenOUdAYrOkg10xnBDJQ2dcd8	false	flag tag:?-?|necessary binding region:1-24|mutation disrupting interaction:8-8,10-10|mutation disrupting interaction:8-8,10-10,12-12	myc tag:?-?|mutation with no effect:318-318,321-321	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q8VSP9	uniprotkb:P28482	intact:EBI-6506625|uniprotkb:Q2ET10|uniprotkb:Q2ET14|uniprotkb:Q6XW10|uniprotkb:Q7BEG0|uniprotkb:Q99Q87	intact:EBI-959949|uniprotkb:A8CZ64|ensembl:ENSP00000215832.7|ensembl:ENSP00000381803.3	psi-mi:ospf_shifl(display_long)|uniprotkb:ospF(gene name)|psi-mi:ospF(display_short)|uniprotkb:mkaD(gene name synonym)|uniprotkb:Effector protein OspF(gene name synonym)|uniprotkb:pWR501_0013(orf name)|uniprotkb:SFLP011(orf name)|uniprotkb:CP0010(locus name)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Zhu et al. (2007)	imex:IM-28467|pubmed:18060821	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435272|imex:IM-28467-7	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|refseq:NP_858143.1|refseq:YP_006960239.1|refseq:WP_001121867.1|interpro:IPR038498|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|rcsb pdb:3I0U|refseq:WP_010921598.1|mint:Q8VSP9"	"efo:""Orphanet:261330""|dip:DIP-519N|ensembl:ENSG00000100030.15(gene)|ensembl:ENST00000215832.11(transcript)|ensembl:ENST00000398822.7(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007611""(learning or memory)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0014044""(Schwann cell development)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019858""(cytosine metabolic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030641""(regulation of cellular pH)|go:""GO:0030878""(thyroid gland development)|go:""GO:0031143""(pseudopodium)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042473""(outer ear morphogenesis)|go:""GO:0042552""(myelination)|go:""GO:0042802""(identical protein binding)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0043401""(steroid hormone receptor signaling pathway)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060324""(face development)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0060440""(trachea formation)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0061308""(cardiac neural crest cell development involved in heart development)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070849""(response to epidermal growth factor)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:P28482|rcsb pdb:1PME|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|rcsb pdb:7AUV|rcsb pdb:7E73|rcsb pdb:7E75|rcsb pdb:7NQQ|rcsb pdb:7NQW|rcsb pdb:7NR3|rcsb pdb:7NR5|rcsb pdb:7NR8|rcsb pdb:7NR9|rcsb pdb:7OPM|rcsb pdb:7W5O|rcsb pdb:7X4U|rcsb pdb:7XC1|rcsb pdb:8AO2|rcsb pdb:8AO3|rcsb pdb:8AO4|rcsb pdb:8AO5|rcsb pdb:8AO6|rcsb pdb:8AO7|rcsb pdb:8AO8|rcsb pdb:8AO9|rcsb pdb:8AOA|rcsb pdb:8AOB|rcsb pdb:8AOC|rcsb pdb:8AOD|rcsb pdb:8AOE|rcsb pdb:8AOF|rcsb pdb:8AOG|rcsb pdb:8AOH|rcsb pdb:8AOI|rcsb pdb:8AOJ|rcsb pdb:8PSR|rcsb pdb:8PST|rcsb pdb:8PSW|rcsb pdb:8PSY|rcsb pdb:8PT0|rcsb pdb:8PT1|rcsb pdb:8PT3|rcsb pdb:8PT5|rcsb pdb:8U8J|rcsb pdb:8U8K|rcsb pdb:8ZJV|reactome:R-HSA-111995|reactome:R-HSA-112409|reactome:R-HSA-112411|reactome:R-HSA-1181150|reactome:R-HSA-1295596|reactome:R-HSA-1502540|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-877300|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-9725371|reactome:R-HSA-9732724|reactome:R-HSA-9768919|reactome:R-HSA-982772|reactome:R-HSA-9842640|reactome:R-HSA-9856649|refseq:NP_002736.3|refseq:NP_620407.1|panther:PTHR24055(orthology-group)"	-	-	-	figure legend:fig. 3c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2025/02/26	rogid:mSCbX2cDlV97OQC/v4kEJtqiOIU623	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	intact-crc:6A500C78A5740A2C|rigid:cUYenOUdAYrOkg10xnBDJQ2dcd8	false	glutathione s tranferase tag:?-?|binding-associated region:1-26	myc tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P0A2M9	uniprotkb:P28482	intact:EBI-15676035|uniprotkb:P21456	intact:EBI-959949|uniprotkb:A8CZ64|ensembl:ENSP00000215832.7|ensembl:ENSP00000381803.3	psi-mi:spvc_salty(display_long)|uniprotkb:spvC(gene name)|psi-mi:spvC(display_short)|uniprotkb:27.5 kDa virulence protein(gene name synonym)|uniprotkb:Secreted effector protein SpvC(gene name synonym)|uniprotkb:mkaD(gene name synonym)|uniprotkb:vsdD(gene name synonym)|uniprotkb:PSLT038(locus name)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Zhu et al. (2007)	imex:IM-28467|pubmed:18060821	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26436095|imex:IM-28467-17	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P0A2M9|refseq:NP_490528.1|refseq:WP_001122242.1|dip:DIP-46403N|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|interpro:IPR038498|rcsb pdb:2P1W|rcsb pdb:2Q8Y|rcsb pdb:2Z8M|rcsb pdb:2Z8N|rcsb pdb:2Z8O|rcsb pdb:2Z8P|rcsb pdb:4H43|rcsb pdb:4HAH"	"efo:""Orphanet:261330""|dip:DIP-519N|ensembl:ENSG00000100030.15(gene)|ensembl:ENST00000215832.11(transcript)|ensembl:ENST00000398822.7(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007611""(learning or memory)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0014044""(Schwann cell development)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019858""(cytosine metabolic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030641""(regulation of cellular pH)|go:""GO:0030878""(thyroid gland development)|go:""GO:0031143""(pseudopodium)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042473""(outer ear morphogenesis)|go:""GO:0042552""(myelination)|go:""GO:0042802""(identical protein binding)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0043401""(steroid hormone receptor signaling pathway)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060324""(face development)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0060440""(trachea formation)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0061308""(cardiac neural crest cell development involved in heart development)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070849""(response to epidermal growth factor)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:P28482|rcsb pdb:1PME|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|rcsb pdb:7AUV|rcsb pdb:7E73|rcsb pdb:7E75|rcsb pdb:7NQQ|rcsb pdb:7NQW|rcsb pdb:7NR3|rcsb pdb:7NR5|rcsb pdb:7NR8|rcsb pdb:7NR9|rcsb pdb:7OPM|rcsb pdb:7W5O|rcsb pdb:7X4U|rcsb pdb:7XC1|rcsb pdb:8AO2|rcsb pdb:8AO3|rcsb pdb:8AO4|rcsb pdb:8AO5|rcsb pdb:8AO6|rcsb pdb:8AO7|rcsb pdb:8AO8|rcsb pdb:8AO9|rcsb pdb:8AOA|rcsb pdb:8AOB|rcsb pdb:8AOC|rcsb pdb:8AOD|rcsb pdb:8AOE|rcsb pdb:8AOF|rcsb pdb:8AOG|rcsb pdb:8AOH|rcsb pdb:8AOI|rcsb pdb:8AOJ|rcsb pdb:8PSR|rcsb pdb:8PST|rcsb pdb:8PSW|rcsb pdb:8PSY|rcsb pdb:8PT0|rcsb pdb:8PT1|rcsb pdb:8PT3|rcsb pdb:8PT5|rcsb pdb:8U8J|rcsb pdb:8U8K|rcsb pdb:8ZJV|reactome:R-HSA-111995|reactome:R-HSA-112409|reactome:R-HSA-112411|reactome:R-HSA-1181150|reactome:R-HSA-1295596|reactome:R-HSA-1502540|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-877300|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-9725371|reactome:R-HSA-9732724|reactome:R-HSA-9768919|reactome:R-HSA-982772|reactome:R-HSA-9842640|reactome:R-HSA-9856649|refseq:NP_002736.3|refseq:NP_620407.1|panther:PTHR24055(orthology-group)"	-	crc64:77625271D78F8814	-	figure legend:suppl fig 4a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2025/02/26	rogid:MezetuISvipnkk4GUAaruDCjolg99287	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	intact-crc:805582A3597F85FB|rigid:/5517FYB5Ed3ink/cC+MMNlrNnc	false	mutation disrupting interaction:136-136|mutation causing an interaction:136-136|mutation disrupting interaction:106-106|mutation disrupting interaction:106-106|mutation disrupting interaction:106-106,136-136	biotin tag:?-?|binding-associated region:179-191	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P0A2M9	uniprotkb:P28482	intact:EBI-15676035|uniprotkb:P21456	intact:EBI-959949|uniprotkb:A8CZ64|ensembl:ENSP00000215832.7|ensembl:ENSP00000381803.3	psi-mi:spvc_salty(display_long)|uniprotkb:spvC(gene name)|psi-mi:spvC(display_short)|uniprotkb:27.5 kDa virulence protein(gene name synonym)|uniprotkb:Secreted effector protein SpvC(gene name synonym)|uniprotkb:mkaD(gene name synonym)|uniprotkb:vsdD(gene name synonym)|uniprotkb:PSLT038(locus name)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Zhu et al. (2007)	imex:IM-28467|pubmed:18060821	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0203""(dephosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435854|imex:IM-28467-9	intact-miscore:0.68	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P0A2M9|refseq:NP_490528.1|refseq:WP_001122242.1|dip:DIP-46403N|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|interpro:IPR038498|rcsb pdb:2P1W|rcsb pdb:2Q8Y|rcsb pdb:2Z8M|rcsb pdb:2Z8N|rcsb pdb:2Z8O|rcsb pdb:2Z8P|rcsb pdb:4H43|rcsb pdb:4HAH"	"efo:""Orphanet:261330""|dip:DIP-519N|ensembl:ENSG00000100030.15(gene)|ensembl:ENST00000215832.11(transcript)|ensembl:ENST00000398822.7(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007611""(learning or memory)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0014044""(Schwann cell development)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019858""(cytosine metabolic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030641""(regulation of cellular pH)|go:""GO:0030878""(thyroid gland development)|go:""GO:0031143""(pseudopodium)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042473""(outer ear morphogenesis)|go:""GO:0042552""(myelination)|go:""GO:0042802""(identical protein binding)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0043401""(steroid hormone receptor signaling pathway)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060324""(face development)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0060440""(trachea formation)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0061308""(cardiac neural crest cell development involved in heart development)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070849""(response to epidermal growth factor)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:P28482|rcsb pdb:1PME|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|rcsb pdb:7AUV|rcsb pdb:7E73|rcsb pdb:7E75|rcsb pdb:7NQQ|rcsb pdb:7NQW|rcsb pdb:7NR3|rcsb pdb:7NR5|rcsb pdb:7NR8|rcsb pdb:7NR9|rcsb pdb:7OPM|rcsb pdb:7W5O|rcsb pdb:7X4U|rcsb pdb:7XC1|rcsb pdb:8AO2|rcsb pdb:8AO3|rcsb pdb:8AO4|rcsb pdb:8AO5|rcsb pdb:8AO6|rcsb pdb:8AO7|rcsb pdb:8AO8|rcsb pdb:8AO9|rcsb pdb:8AOA|rcsb pdb:8AOB|rcsb pdb:8AOC|rcsb pdb:8AOD|rcsb pdb:8AOE|rcsb pdb:8AOF|rcsb pdb:8AOG|rcsb pdb:8AOH|rcsb pdb:8AOI|rcsb pdb:8AOJ|rcsb pdb:8PSR|rcsb pdb:8PST|rcsb pdb:8PSW|rcsb pdb:8PSY|rcsb pdb:8PT0|rcsb pdb:8PT1|rcsb pdb:8PT3|rcsb pdb:8PT5|rcsb pdb:8U8J|rcsb pdb:8U8K|rcsb pdb:8ZJV|reactome:R-HSA-111995|reactome:R-HSA-112409|reactome:R-HSA-112411|reactome:R-HSA-1181150|reactome:R-HSA-1295596|reactome:R-HSA-1502540|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-877300|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-9725371|reactome:R-HSA-9732724|reactome:R-HSA-9768919|reactome:R-HSA-982772|reactome:R-HSA-9842640|reactome:R-HSA-9856649|refseq:NP_002736.3|refseq:NP_620407.1|panther:PTHR24055(orthology-group)"	-	crc64:77625271D78F8814	-	figure legend:table 2 fig.6c suppl table1 suppl.fig. 6,7|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2025/02/26	rogid:MezetuISvipnkk4GUAaruDCjolg99287	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	intact-crc:2534A8F02A5469C0|rigid:/5517FYB5Ed3ink/cC+MMNlrNnc	false	maltose binding protein tag:?-?|mutation with no effect:134-134|mutation decreasing interaction:134-134|mutation decreasing interaction:160-160|mutation disrupting interaction:160-160|mutation disrupting interaction:100-100|mutation disrupting interaction:148-148|mutation disrupting interaction:213-213|mutation disrupting interaction:104-104|mutation disrupting interaction:136-136|mutation disrupting interaction:136-136|mutation disrupting interaction:106-106|mutation decreasing interaction:201-201|mutation with no effect:158-158|mutation with no effect:106-106|mutation disrupting interaction:220-220	binding-associated region:179-191|O4'-phospho-L-tyrosine:187-187	-	-	"psi-mi:""MI:1323""(tag visualisation by alkaline phosphatase activity)"	"psi-mi:""MI:1323""(tag visualisation by alkaline phosphatase activity)"
uniprotkb:Q8VSP9	uniprotkb:P28482	intact:EBI-6506625|uniprotkb:Q2ET10|uniprotkb:Q2ET14|uniprotkb:Q6XW10|uniprotkb:Q7BEG0|uniprotkb:Q99Q87	intact:EBI-959949|uniprotkb:A8CZ64|ensembl:ENSP00000215832.7|ensembl:ENSP00000381803.3	psi-mi:ospf_shifl(display_long)|uniprotkb:ospF(gene name)|psi-mi:ospF(display_short)|uniprotkb:mkaD(gene name synonym)|uniprotkb:Effector protein OspF(gene name synonym)|uniprotkb:pWR501_0013(orf name)|uniprotkb:SFLP011(orf name)|uniprotkb:CP0010(locus name)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Zhu et al. (2007)	imex:IM-28467|pubmed:18060821	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0203""(dephosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26436042|imex:IM-28467-11	intact-miscore:0.67	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|refseq:NP_858143.1|refseq:YP_006960239.1|refseq:WP_001121867.1|interpro:IPR038498|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|rcsb pdb:3I0U|refseq:WP_010921598.1|mint:Q8VSP9"	"efo:""Orphanet:261330""|dip:DIP-519N|ensembl:ENSG00000100030.15(gene)|ensembl:ENST00000215832.11(transcript)|ensembl:ENST00000398822.7(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007611""(learning or memory)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0014044""(Schwann cell development)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019858""(cytosine metabolic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030641""(regulation of cellular pH)|go:""GO:0030878""(thyroid gland development)|go:""GO:0031143""(pseudopodium)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042473""(outer ear morphogenesis)|go:""GO:0042552""(myelination)|go:""GO:0042802""(identical protein binding)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0043401""(steroid hormone receptor signaling pathway)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060324""(face development)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0060440""(trachea formation)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0061308""(cardiac neural crest cell development involved in heart development)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070849""(response to epidermal growth factor)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:P28482|rcsb pdb:1PME|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|rcsb pdb:7AUV|rcsb pdb:7E73|rcsb pdb:7E75|rcsb pdb:7NQQ|rcsb pdb:7NQW|rcsb pdb:7NR3|rcsb pdb:7NR5|rcsb pdb:7NR8|rcsb pdb:7NR9|rcsb pdb:7OPM|rcsb pdb:7W5O|rcsb pdb:7X4U|rcsb pdb:7XC1|rcsb pdb:8AO2|rcsb pdb:8AO3|rcsb pdb:8AO4|rcsb pdb:8AO5|rcsb pdb:8AO6|rcsb pdb:8AO7|rcsb pdb:8AO8|rcsb pdb:8AO9|rcsb pdb:8AOA|rcsb pdb:8AOB|rcsb pdb:8AOC|rcsb pdb:8AOD|rcsb pdb:8AOE|rcsb pdb:8AOF|rcsb pdb:8AOG|rcsb pdb:8AOH|rcsb pdb:8AOI|rcsb pdb:8AOJ|rcsb pdb:8PSR|rcsb pdb:8PST|rcsb pdb:8PSW|rcsb pdb:8PSY|rcsb pdb:8PT0|rcsb pdb:8PT1|rcsb pdb:8PT3|rcsb pdb:8PT5|rcsb pdb:8U8J|rcsb pdb:8U8K|rcsb pdb:8ZJV|reactome:R-HSA-111995|reactome:R-HSA-112409|reactome:R-HSA-112411|reactome:R-HSA-1181150|reactome:R-HSA-1295596|reactome:R-HSA-1502540|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-877300|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-9725371|reactome:R-HSA-9732724|reactome:R-HSA-9768919|reactome:R-HSA-982772|reactome:R-HSA-9842640|reactome:R-HSA-9856649|refseq:NP_002736.3|refseq:NP_620407.1|panther:PTHR24055(orthology-group)"	-	-	-	figure legend:fig. 5c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2025/02/26	rogid:mSCbX2cDlV97OQC/v4kEJtqiOIU623	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	intact-crc:22A6F77A3E2758B8|rigid:cUYenOUdAYrOkg10xnBDJQ2dcd8	false	glutathione s tranferase tag:?-?	binding-associated region:179-191|O4'-phospho-L-tyrosine:187-187	-	-	"psi-mi:""MI:1323""(tag visualisation by alkaline phosphatase activity)"	"psi-mi:""MI:1323""(tag visualisation by alkaline phosphatase activity)"
uniprotkb:Q8VSP9	uniprotkb:Q16539	intact:EBI-6506625|uniprotkb:Q2ET10|uniprotkb:Q2ET14|uniprotkb:Q6XW10|uniprotkb:Q7BEG0|uniprotkb:Q99Q87	intact:EBI-73946|uniprotkb:A8K6P4|uniprotkb:B0LPH0|uniprotkb:A6ZJ92|uniprotkb:O60776|uniprotkb:Q13083|uniprotkb:Q14084|uniprotkb:Q8TDX0|uniprotkb:B5TY32|ensembl:ENSP00000229794.4	psi-mi:ospf_shifl(display_long)|uniprotkb:ospF(gene name)|psi-mi:ospF(display_short)|uniprotkb:mkaD(gene name synonym)|uniprotkb:Effector protein OspF(gene name synonym)|uniprotkb:pWR501_0013(orf name)|uniprotkb:SFLP011(orf name)|uniprotkb:CP0010(locus name)	psi-mi:mk14_human(display_long)|uniprotkb:Mitogen-activated protein kinase p38 alpha(gene name synonym)|uniprotkb:Cytokine suppressive anti-inflammatory drug-binding protein(gene name synonym)|uniprotkb:MAX-interacting protein 2(gene name synonym)|uniprotkb:MAP kinase MXI2(gene name synonym)|uniprotkb:SAPK2A(gene name synonym)|uniprotkb:MAPK14(gene name)|psi-mi:MAPK14(display_short)|uniprotkb:CSBP(gene name synonym)|uniprotkb:CSBP1(gene name synonym)|uniprotkb:CSBP2(gene name synonym)|uniprotkb:CSPB1(gene name synonym)|uniprotkb:MXI2(gene name synonym)|uniprotkb:Stress-activated protein kinase 2a(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Zhu et al. (2007)	imex:IM-28467|pubmed:18060821	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0203""(dephosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26436068|imex:IM-28467-13	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|refseq:NP_858143.1|refseq:YP_006960239.1|refseq:WP_001121867.1|interpro:IPR038498|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|rcsb pdb:3I0U|refseq:WP_010921598.1|mint:Q8VSP9"	"refseq:NP_001306.1|refseq:NP_620581.1|refseq:NP_620582.1|refseq:NP_620583.1|panther:PTHR24055(orthology-group)|dip:DIP-30987N|ensembl:ENSG00000112062.13(gene)|ensembl:ENST00000229794.9(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0000922""(spindle pole)|go:""GO:0001502""(cartilage condensation)|go:""GO:0001525""(angiogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001890""(placenta development)|go:""GO:0002021""(response to dietary excess)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0004708""(MAP kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007178""(cell surface receptor protein serine/threonine kinase signaling pathway)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010831""(positive regulation of myotube differentiation)|go:""GO:0016607""(nuclear speck)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019395""(fatty acid oxidation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030168""(platelet activation)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0031098""(stress-activated protein kinase signaling cascade)|go:""GO:0031281""(positive regulation of cyclase activity)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032868""(response to insulin)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046323""(D-glucose import)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048273""(mitogen-activated protein kinase p38 binding)|go:""GO:0048863""(stem cell differentiation)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051525""(NFAT protein binding)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060348""(bone development)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0071493""(cellular response to UV-B)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0090336""(positive regulation of brown fat cell differentiation)|go:""GO:0090398""(cellular senescence)|go:""GO:0090400""(stress-induced premature senescence)|go:""GO:0098586""(cellular response to virus)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099179""(regulation of synaptic membrane adhesion)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1900015""(regulation of cytokine production involved in inflammatory response)|go:""GO:1901741""(positive regulation of myoblast fusion)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038784|interpro:IPR050117|mint:Q16539|rcsb pdb:1A9U|rcsb pdb:1BL6|rcsb pdb:1BL7|rcsb pdb:1BMK|rcsb pdb:1DI9|rcsb pdb:1IAN|rcsb pdb:1KV1|rcsb pdb:1KV2|rcsb pdb:1M7Q|rcsb pdb:1OUK|rcsb pdb:1OUY|rcsb pdb:1OVE|rcsb pdb:1OZ1|rcsb pdb:1R39|rcsb pdb:1R3C|rcsb pdb:1W7H|rcsb pdb:1W82|rcsb pdb:1W83|rcsb pdb:1W84|rcsb pdb:1WBN|rcsb pdb:1WBO|rcsb pdb:1WBS|rcsb pdb:1WBT|rcsb pdb:1WBV|rcsb pdb:1WBW|rcsb pdb:1WFC|rcsb pdb:1YQJ|rcsb pdb:1ZYJ|rcsb pdb:1ZZ2|rcsb pdb:1ZZL|rcsb pdb:2BAJ|rcsb pdb:2BAK|rcsb pdb:2BAL|rcsb pdb:2BAQ|rcsb pdb:2FSL|rcsb pdb:2FSM|rcsb pdb:2FSO|rcsb pdb:2FST|rcsb pdb:2GFS|rcsb pdb:2I0H|rcsb pdb:2LGC|rcsb pdb:2NPQ|rcsb pdb:2OKR|rcsb pdb:2ONL|rcsb pdb:2QD9|rcsb pdb:2RG5|rcsb pdb:2RG6|rcsb pdb:2Y8O|rcsb pdb:2YIS|rcsb pdb:2YIW|rcsb pdb:2YIX|rcsb pdb:2ZAZ|rcsb pdb:2ZB0|rcsb pdb:2ZB1|rcsb pdb:3BV2|rcsb pdb:3BV3|rcsb pdb:3BX5|rcsb pdb:3C5U|rcsb pdb:3CTQ|rcsb pdb:3D7Z|rcsb pdb:3D83|rcsb pdb:3DS6|rcsb pdb:3DT1|rcsb pdb:3E92|rcsb pdb:3E93|rcsb pdb:3FC1|rcsb pdb:3FI4|rcsb pdb:3FKL|rcsb pdb:3FKN|rcsb pdb:3FKO|rcsb pdb:3FL4|rcsb pdb:3FLN|rcsb pdb:3FLQ|rcsb pdb:3FLS|rcsb pdb:3FLW|rcsb pdb:3FLY|rcsb pdb:3FLZ|rcsb pdb:3FMH|rcsb pdb:3FMJ|rcsb pdb:3FMK|rcsb pdb:3FML|rcsb pdb:3FMM|rcsb pdb:3FMN|rcsb pdb:3FSF|rcsb pdb:3FSK|rcsb pdb:3GC7|rcsb pdb:3GCP|rcsb pdb:3GCQ|rcsb pdb:3GCS|rcsb pdb:3GCU|rcsb pdb:3GCV|rcsb pdb:3GFE|rcsb pdb:3GI3|rcsb pdb:3HA8|rcsb pdb:3HEC|rcsb pdb:3HEG|rcsb pdb:3HL7|rcsb pdb:3HLL|rcsb pdb:3HP2|rcsb pdb:3HP5|rcsb pdb:3HRB|rcsb pdb:3HUB|rcsb pdb:3HUC|rcsb pdb:3HV3|rcsb pdb:3HV4|rcsb pdb:3HV5|rcsb pdb:3HV6|rcsb pdb:3HV7|rcsb pdb:3HVC|rcsb pdb:3IPH|rcsb pdb:3ITZ|rcsb pdb:3IW5|rcsb pdb:3IW6|rcsb pdb:3IW7|rcsb pdb:3IW8|rcsb pdb:3K3I|rcsb pdb:3K3J|rcsb pdb:3KF7|rcsb pdb:3KQ7|rcsb pdb:3L8S|rcsb pdb:3L8X|rcsb pdb:3LFA|rcsb pdb:3LFB|rcsb pdb:3LFC|rcsb pdb:3LFD|rcsb pdb:3LFE|rcsb pdb:3LFF|rcsb pdb:3LHJ|rcsb pdb:3MGY|rcsb pdb:3MH0|rcsb pdb:3MH1|rcsb pdb:3MH2|rcsb pdb:3MH3|rcsb pdb:3MPA|rcsb pdb:3MPT|rcsb pdb:3MVL|rcsb pdb:3MVM|rcsb pdb:3MW1|rcsb pdb:3NEW|rcsb pdb:3NNU|rcsb pdb:3NNV|rcsb pdb:3NNW|rcsb pdb:3NNX|rcsb pdb:3NWW|rcsb pdb:3O8P|rcsb pdb:3O8T|rcsb pdb:3O8U|rcsb pdb:3OBG|rcsb pdb:3OBJ|rcsb pdb:3OC1|rcsb pdb:3OCG|rcsb pdb:3OD6|rcsb pdb:3ODY|rcsb pdb:3ODZ|rcsb pdb:3OEF|rcsb pdb:3PG3|rcsb pdb:3QUD|rcsb pdb:3QUE|rcsb pdb:3RIN|rcsb pdb:3ROC|rcsb pdb:3S3I|rcsb pdb:3S4Q|rcsb pdb:3U8W|rcsb pdb:3UVP|rcsb pdb:3UVQ|rcsb pdb:3UVR|rcsb pdb:3ZS5|rcsb pdb:3ZSG|rcsb pdb:3ZSH|rcsb pdb:3ZSI|rcsb pdb:3ZYA|rcsb pdb:4A9Y|rcsb pdb:4AA0|rcsb pdb:4AA4|rcsb pdb:4AA5|rcsb pdb:4AAC|rcsb pdb:4DLI|rcsb pdb:4DLJ|rcsb pdb:4E5A|rcsb pdb:4E5B|rcsb pdb:4E6A|rcsb pdb:4E6C|rcsb pdb:4E8A|rcsb pdb:4EH2|rcsb pdb:4EH3|rcsb pdb:4EH4|rcsb pdb:4EH5|rcsb pdb:4EH6|rcsb pdb:4EH7|rcsb pdb:4EH8|rcsb pdb:4EH9|rcsb pdb:4EHV|rcsb pdb:4EWQ|rcsb pdb:4F9W|rcsb pdb:4F9Y|rcsb pdb:4FA2|rcsb pdb:4GEO|rcsb pdb:4KIN|rcsb pdb:4KIP|rcsb pdb:4KIQ|rcsb pdb:4L8M|rcsb pdb:4R3C|rcsb pdb:4ZTH|rcsb pdb:5ETA|rcsb pdb:5ETC|rcsb pdb:5ETF|rcsb pdb:5ETI|rcsb pdb:5ML5|rcsb pdb:5MTX|rcsb pdb:5MTY|rcsb pdb:5MZ3|rcsb pdb:5N63|rcsb pdb:5N64|rcsb pdb:5N65|rcsb pdb:5N66|rcsb pdb:5N67|rcsb pdb:5N68|rcsb pdb:5O8U|rcsb pdb:5O8V|rcsb pdb:5OMG|rcsb pdb:5OMH|rcsb pdb:5TBE|rcsb pdb:5TCO|rcsb pdb:5WJJ|rcsb pdb:5XYX|rcsb pdb:5XYY|rcsb pdb:6ANL|rcsb pdb:6HWT|rcsb pdb:6HWU|rcsb pdb:6HWV|rcsb pdb:6M95|rcsb pdb:6M9L|rcsb pdb:6OHD|rcsb pdb:6QDZ|rcsb pdb:6QE1|rcsb pdb:6QYX|rcsb pdb:6RFO|rcsb pdb:6SFI|rcsb pdb:6SFJ|rcsb pdb:6SFK|rcsb pdb:6SFO|rcsb pdb:6TCA|rcsb pdb:6ZQS|rcsb pdb:6ZWP|rcsb pdb:8A8M|rcsb pdb:8VXE|reactome:R-HSA-168638|reactome:R-HSA-171007|reactome:R-HSA-198753|reactome:R-HSA-2151209|reactome:R-HSA-2559580|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-4420097|reactome:R-HSA-450302|reactome:R-HSA-450341|reactome:R-HSA-450604|reactome:R-HSA-525793|reactome:R-HSA-5668599|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-9662834|reactome:R-HSA-9824585|ensembl:ENSP00000229794.4|ensembl:ENST00000229795.8|ensembl:ENSP00000229795.3|ensembl:ENST00000310795.8|ensembl:ENSP00000308669.4"	-	-	-	figure legend:fig. 5c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2024/11/06	rogid:mSCbX2cDlV97OQC/v4kEJtqiOIU623	rogid:oI6EOrCDVMQ6FDVBHSiYYoKZHns9606	intact-crc:75FBD818B907B8AD|rigid:BIBD8lJL1a7PMZRimTbKwkHaQjU	false	glutathione s tranferase tag:?-?	binding-associated region:179-191|O4'-phospho-L-tyrosine:182-182	-	-	"psi-mi:""MI:1323""(tag visualisation by alkaline phosphatase activity)"	"psi-mi:""MI:1323""(tag visualisation by alkaline phosphatase activity)"
uniprotkb:Q8VSP9	uniprotkb:P28482	intact:EBI-6506625|uniprotkb:Q2ET10|uniprotkb:Q2ET14|uniprotkb:Q6XW10|uniprotkb:Q7BEG0|uniprotkb:Q99Q87	intact:EBI-959949|uniprotkb:A8CZ64|ensembl:ENSP00000215832.7|ensembl:ENSP00000381803.3	psi-mi:ospf_shifl(display_long)|uniprotkb:ospF(gene name)|psi-mi:ospF(display_short)|uniprotkb:mkaD(gene name synonym)|uniprotkb:Effector protein OspF(gene name synonym)|uniprotkb:pWR501_0013(orf name)|uniprotkb:SFLP011(orf name)|uniprotkb:CP0010(locus name)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	"psi-mi:""MI:0071""(molecular sieving)"	Zhu et al. (2007)	imex:IM-28467|pubmed:18060821	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26436085|imex:IM-28467-15	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|refseq:NP_858143.1|refseq:YP_006960239.1|refseq:WP_001121867.1|interpro:IPR038498|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|rcsb pdb:3I0U|refseq:WP_010921598.1|mint:Q8VSP9"	"efo:""Orphanet:261330""|dip:DIP-519N|ensembl:ENSG00000100030.15(gene)|ensembl:ENST00000215832.11(transcript)|ensembl:ENST00000398822.7(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007611""(learning or memory)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0014044""(Schwann cell development)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019858""(cytosine metabolic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030641""(regulation of cellular pH)|go:""GO:0030878""(thyroid gland development)|go:""GO:0031143""(pseudopodium)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042473""(outer ear morphogenesis)|go:""GO:0042552""(myelination)|go:""GO:0042802""(identical protein binding)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0043401""(steroid hormone receptor signaling pathway)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060324""(face development)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0060440""(trachea formation)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0061308""(cardiac neural crest cell development involved in heart development)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070849""(response to epidermal growth factor)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:P28482|rcsb pdb:1PME|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|rcsb pdb:7AUV|rcsb pdb:7E73|rcsb pdb:7E75|rcsb pdb:7NQQ|rcsb pdb:7NQW|rcsb pdb:7NR3|rcsb pdb:7NR5|rcsb pdb:7NR8|rcsb pdb:7NR9|rcsb pdb:7OPM|rcsb pdb:7W5O|rcsb pdb:7X4U|rcsb pdb:7XC1|rcsb pdb:8AO2|rcsb pdb:8AO3|rcsb pdb:8AO4|rcsb pdb:8AO5|rcsb pdb:8AO6|rcsb pdb:8AO7|rcsb pdb:8AO8|rcsb pdb:8AO9|rcsb pdb:8AOA|rcsb pdb:8AOB|rcsb pdb:8AOC|rcsb pdb:8AOD|rcsb pdb:8AOE|rcsb pdb:8AOF|rcsb pdb:8AOG|rcsb pdb:8AOH|rcsb pdb:8AOI|rcsb pdb:8AOJ|rcsb pdb:8PSR|rcsb pdb:8PST|rcsb pdb:8PSW|rcsb pdb:8PSY|rcsb pdb:8PT0|rcsb pdb:8PT1|rcsb pdb:8PT3|rcsb pdb:8PT5|rcsb pdb:8U8J|rcsb pdb:8U8K|rcsb pdb:8ZJV|reactome:R-HSA-111995|reactome:R-HSA-112409|reactome:R-HSA-112411|reactome:R-HSA-1181150|reactome:R-HSA-1295596|reactome:R-HSA-1502540|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-877300|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-9725371|reactome:R-HSA-9732724|reactome:R-HSA-9768919|reactome:R-HSA-982772|reactome:R-HSA-9842640|reactome:R-HSA-9856649|refseq:NP_002736.3|refseq:NP_620407.1|panther:PTHR24055(orthology-group)"	-	-	-	figure legend:suppl.fig 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2025/02/26	rogid:mSCbX2cDlV97OQC/v4kEJtqiOIU623	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	intact-crc:0DE83A65D630807A|rigid:cUYenOUdAYrOkg10xnBDJQ2dcd8	false	binding-associated region:1-24|glutathione s tranferase tag:?-?	his tag:?-?	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:P0A2M9	uniprotkb:Q13164	intact:EBI-15676035|uniprotkb:P21456	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|ensembl:ENSP00000311005.5|ensembl:ENSP00000378966.4|ensembl:ENSP00000378968.3|intact:EBI-28979986	psi-mi:spvc_salty(display_long)|uniprotkb:spvC(gene name)|psi-mi:spvC(display_short)|uniprotkb:27.5 kDa virulence protein(gene name synonym)|uniprotkb:Secreted effector protein SpvC(gene name synonym)|uniprotkb:mkaD(gene name synonym)|uniprotkb:vsdD(gene name synonym)|uniprotkb:PSLT038(locus name)	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Zhu et al. (2007)	imex:IM-28467|pubmed:18060821	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26436139|imex:IM-28467-19	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P0A2M9|refseq:NP_490528.1|refseq:WP_001122242.1|dip:DIP-46403N|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|interpro:IPR038498|rcsb pdb:2P1W|rcsb pdb:2Q8Y|rcsb pdb:2Z8M|rcsb pdb:2Z8N|rcsb pdb:2Z8O|rcsb pdb:2Z8P|rcsb pdb:4H43|rcsb pdb:4HAH"	"refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|refseq:XP_011522259.1|ensembl:ENSG00000166484.20(gene)|ensembl:ENST00000308406.9(transcript)|ensembl:ENST00000395602.8(transcript)|ensembl:ENST00000395604.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0016605""(PML body)|go:""GO:0030154""(cell differentiation)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0034115""(negative regulation of heterotypic cell-cell adhesion)|go:""GO:0034392""(negative regulation of smooth muscle cell apoptotic process)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071499""(cellular response to laminar fluid shear stress)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|rcsb pdb:7PUS|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|panther:PTHR24055(orthology-group)|ensembl:ENST00000299612.11|ensembl:ENSP00000299612.7|ensembl:ENSP00000311005.5|ensembl:ENSP00000378966.4|ensembl:ENSP00000378968.3"	-	crc64:77625271D78F8814	-	figure legend:suppl.fig 4b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:102.0x10^-6(molar)	2020/10/13	2024/11/14	rogid:MezetuISvipnkk4GUAaruDCjolg99287	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	intact-crc:0814185F9CE36742|rigid:ngh8iClDj5w0dntT/v6Iyo3vOdc	false	mutation causing an interaction:136-136|mutation disrupting interaction:136-136,106-106	binding-associated region:213-225	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q2GHU2	uniprotkb:Q86SE9	intact:EBI-26585631	intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500.5|ensembl:ENSP00000445704.1|ensembl:ENSP00000479492.1	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26585629|imex:IM-28642-1	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q2GHU2	"refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|ensembl:ENSG00000180628.15(gene)|ensembl:ENST00000336126.6(transcript)|ensembl:ENST00000543648.5(transcript)|ensembl:ENST00000614189.4(transcript)|go:""GO:0000805""(X chromosome)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0140862""(histone H2AK119 ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR051507|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|panther:PTHR45893(orthology-group)"	-	-	-	figure legend:fig.2 table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/12/02	2025/01/27	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606	intact-crc:DAB11C57111B302C|rigid:A0H/eTxEptyOTe9UuwWFLhqEkvQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q2GHU2	uniprotkb:P06241	intact:EBI-26585631	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671.3|ensembl:ENSP00000357656.2	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26585659|imex:IM-28642-3	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q2GHU2	"refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|ensembl:ENSG00000010810.18(gene)|ensembl:ENST00000354650.7(transcript)|ensembl:ENST00000368667.6(transcript)|go:""GO:0000304""(response to singlet oxygen)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001764""(neuron migration)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0003015""(heart process)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007216""(G protein-coupled glutamate receptor signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0007612""(learning)|go:""GO:0007631""(feeding behavior)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010467""(gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010730""(negative regulation of hydrogen peroxide biosynthetic process)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030425""(dendrite)|go:""GO:0030900""(forebrain development)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031802""(type 5 metabotropic glutamate receptor binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0038026""(reelin-mediated signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0043204""(perikaryon)|go:""GO:0043274""(phospholipase binding)|go:""GO:0044297""(cell body)|go:""GO:0044325""(transmembrane transporter binding)|interpro:IPR035750|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045471""(response to ethanol)|go:""GO:0046872""(metal ion binding)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050798""(activated T cell proliferation)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050900""(leukocyte migration)|go:""GO:0050966""(detection of mechanical stimulus involved in sensory perception of pain)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070851""(growth factor receptor binding)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097386""(glial cell projection)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1900449""(regulation of glutamate receptor signaling pathway)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902951""(negative regulation of dendritic spine maintenance)|go:""GO:1904645""(response to amyloid-beta)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:1905430""(cellular response to glycine)|go:""GO:1905477""(positive regulation of protein localization to membrane)|go:""GO:1905664""(regulation of calcium ion import across plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|interpro:IPR047924|interpro:IPR050198|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|rcsb pdb:7A2J|rcsb pdb:7A2K|rcsb pdb:7A2L|rcsb pdb:7A2M|rcsb pdb:7A2N|rcsb pdb:7A2O|rcsb pdb:7A2P|rcsb pdb:7A2Q|rcsb pdb:7A2R|rcsb pdb:7A2S|rcsb pdb:7A2T|rcsb pdb:7A2U|rcsb pdb:7A2V|rcsb pdb:7A2W|rcsb pdb:7A2X|rcsb pdb:7A2Y|rcsb pdb:7A2Z|rcsb pdb:7UD6|rcsb pdb:8KDX|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9680350|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9856530|dip:DIP-33876N|panther:PTHR24418(orthology-group)"	-	-	-	figure legend:fig.2 table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/12/02	2025/03/10	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	intact-crc:9C13E30CED2221FF|rigid:+QhjIMUSVILY+O/ld9eT4FmaYLM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q2GHU2	uniprotkb:P17706	intact:EBI-26585631	intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955|ensembl:ENSP00000311857.3	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26585678|imex:IM-28642-5	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q2GHU2	"ensembl:ENSG00000175354.20(gene)|ensembl:ENST00000309660.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031904""(endosome lumen)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042532""(negative regulation of tyrosine phosphorylation of STAT protein)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0045650""(negative regulation of macrophage differentiation)|go:""GO:0045722""(positive regulation of gluconeogenesis)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050922""(negative regulation of chemotaxis)|go:""GO:0060334""(regulation of type II interferon-mediated signaling pathway)|go:""GO:0060336""(negative regulation of type II interferon-mediated signaling pathway)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0070104""(negative regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902206""(negative regulation of interleukin-2-mediated signaling pathway)|go:""GO:1902215""(negative regulation of interleukin-4-mediated signaling pathway)|go:""GO:1902227""(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:""GO:1902233""(negative regulation of positive thymic T cell selection)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903899""(positive regulation of PERK-mediated unfolded protein response)|go:""GO:2000587""(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P17706|rcsb pdb:1L8K|rcsb pdb:6ZZ4|rcsb pdb:7F5N|rcsb pdb:7F5O|rcsb pdb:7UAD|rcsb pdb:8U0H|rcsb pdb:8UH6|rcsb pdb:9C54|rcsb pdb:9C55|rcsb pdb:9C56|reactome:R-HSA-6807004|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-9833482|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1|efo:""Orphanet:85408""|efo:""Orphanet:85410""|panther:PTHR46047(orthology-group)"	-	-	-	figure legend:fig.2 table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/12/02	2024/11/14	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606	intact-crc:8CC2B1F0262033AE|rigid:L5PqbWQrn3ch28GQ2OVgeTrB6vg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01518	uniprotkb:Q2GHU2	intact:EBI-2808398|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1|ensembl:ENSP00000361878.2|ensembl:ENSP00000361883.3|ensembl:ENSP00000361891.3	intact:EBI-26585631	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26585682|imex:IM-28642-21	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_005270425.1|ensembl:ENSG00000131236.18(gene)|ensembl:ENST00000372792.7(transcript)|ensembl:ENST00000372797.7(transcript)|ensembl:ENST00000372805.8(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001667""(ameboidal-type cell migration)|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007165""(signal transduction)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0019933""(cAMP-mediated signaling)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098885""(modification of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR036222|interpro:IPR036223|interpro:IPR053950|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|dip:DIP-62063N|panther:PTHR10652(orthology-group)"	mint:Q2GHU2	-	crc64:7789D1FAC0D1AB7B	-	figure legend:fig.2 table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/12/02	2025/02/28	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:A949E35E67516C99|rigid:DM4aYs0zj2G6zQ86nJmc3S9Mz5I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q2GHU2	uniprotkb:P15814	intact:EBI-26585631	intact:EBI-1222221|uniprotkb:Q0P681|ensembl:ENSP00000329312.2	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:igll1_human(display_long)|uniprotkb:IGLL1(gene name)|psi-mi:IGLL1(display_short)|uniprotkb:IGL1(gene name synonym)|uniprotkb:Immunoglobulin-related protein 14.1(gene name synonym)|uniprotkb:Immunoglobulin omega polypeptide(gene name synonym)|uniprotkb:Ig lambda-5(gene name synonym)|uniprotkb:CD179 antigen-like family member B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26587344|imex:IM-28642-7	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q2GHU2	"efo:""Orphanet:33110""|ensembl:ENSG00000128322.7(gene)|ensembl:ENST00000330377.3(transcript)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006955""(immune response)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0071735""(IgG immunoglobulin complex)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050160|mint:P15814|rcsb pdb:2H32|rcsb pdb:2H3N|rcsb pdb:2LKQ|reactome:R-HSA-202733|refseq:NP_064455.1|refseq:NP_690594.1|panther:PTHR23266(orthology-group)"	-	-	-	figure legend:fig.2 table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/12/02	2024/11/14	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:BpOlZ3iBc9geHAdkkOm+Z5yCsiU9606	intact-crc:213BE2E81FDDFEFD|rigid:gJEJWeS8Cx/bfZRUGZg56JFSeFw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01518	uniprotkb:Q2GHU2	intact:EBI-2808398|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1|ensembl:ENSP00000361878.2|ensembl:ENSP00000361883.3|ensembl:ENSP00000361891.3	intact:EBI-26585631	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26587348|imex:IM-28642-9	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_005270425.1|ensembl:ENSG00000131236.18(gene)|ensembl:ENST00000372792.7(transcript)|ensembl:ENST00000372797.7(transcript)|ensembl:ENST00000372805.8(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001667""(ameboidal-type cell migration)|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007165""(signal transduction)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0019933""(cAMP-mediated signaling)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098885""(modification of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR036222|interpro:IPR036223|interpro:IPR053950|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|dip:DIP-62063N|panther:PTHR10652(orthology-group)"	mint:Q2GHU2	-	crc64:7789D1FAC0D1AB7B	-	figure legend:fig.3 table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/12/02	2025/02/28	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:DCA61C63D4F7AEF9|rigid:DM4aYs0zj2G6zQ86nJmc3S9Mz5I	false	beta gal tag:n-n	green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P15814	uniprotkb:Q2GHU2	intact:EBI-1222221|uniprotkb:Q0P681|ensembl:ENSP00000329312.2	intact:EBI-26585631	psi-mi:igll1_human(display_long)|uniprotkb:IGLL1(gene name)|psi-mi:IGLL1(display_short)|uniprotkb:IGL1(gene name synonym)|uniprotkb:Immunoglobulin-related protein 14.1(gene name synonym)|uniprotkb:Immunoglobulin omega polypeptide(gene name synonym)|uniprotkb:Ig lambda-5(gene name synonym)|uniprotkb:CD179 antigen-like family member B(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26587367|imex:IM-28642-23	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000128322.7(gene)|ensembl:ENST00000330377.3(transcript)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006955""(immune response)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0071735""(IgG immunoglobulin complex)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050160|mint:P15814|rcsb pdb:2H32|rcsb pdb:2H3N|rcsb pdb:2LKQ|reactome:R-HSA-202733|refseq:NP_064455.1|refseq:NP_690594.1|panther:PTHR23266(orthology-group)"	mint:Q2GHU2	-	-	-	figure legend:fig.3a table1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/12/02	2024/11/14	rogid:BpOlZ3iBc9geHAdkkOm+Z5yCsiU9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:8F98AB96D9DD44D9|rigid:gJEJWeS8Cx/bfZRUGZg56JFSeFw	false	beta gal tag:n-n	green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q86SE9	uniprotkb:Q2GHU2	intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500.5|ensembl:ENSP00000445704.1|ensembl:ENSP00000479492.1	intact:EBI-26585631	psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26587378|imex:IM-28642-11	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|ensembl:ENSG00000180628.15(gene)|ensembl:ENST00000336126.6(transcript)|ensembl:ENST00000543648.5(transcript)|ensembl:ENST00000614189.4(transcript)|go:""GO:0000805""(X chromosome)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0140862""(histone H2AK119 ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR051507|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|panther:PTHR45893(orthology-group)"	mint:Q2GHU2	-	-	-	figure legend:fig.3 table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/12/02	2025/01/27	rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:D98C615418EC489C|rigid:A0H/eTxEptyOTe9UuwWFLhqEkvQ	false	beta gal tag:n-n	green fluorescent protein tag:n-n|sufficient binding region:127-285	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q2GHU2	uniprotkb:P06241	intact:EBI-26585631	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671.3|ensembl:ENSP00000357656.2	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26587389|imex:IM-28642-25	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q2GHU2	"refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|ensembl:ENSG00000010810.18(gene)|ensembl:ENST00000354650.7(transcript)|ensembl:ENST00000368667.6(transcript)|go:""GO:0000304""(response to singlet oxygen)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001764""(neuron migration)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0003015""(heart process)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007216""(G protein-coupled glutamate receptor signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0007612""(learning)|go:""GO:0007631""(feeding behavior)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010467""(gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010730""(negative regulation of hydrogen peroxide biosynthetic process)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030425""(dendrite)|go:""GO:0030900""(forebrain development)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031802""(type 5 metabotropic glutamate receptor binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0038026""(reelin-mediated signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0043204""(perikaryon)|go:""GO:0043274""(phospholipase binding)|go:""GO:0044297""(cell body)|go:""GO:0044325""(transmembrane transporter binding)|interpro:IPR035750|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045471""(response to ethanol)|go:""GO:0046872""(metal ion binding)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050798""(activated T cell proliferation)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050900""(leukocyte migration)|go:""GO:0050966""(detection of mechanical stimulus involved in sensory perception of pain)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070851""(growth factor receptor binding)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097386""(glial cell projection)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1900449""(regulation of glutamate receptor signaling pathway)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902951""(negative regulation of dendritic spine maintenance)|go:""GO:1904645""(response to amyloid-beta)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:1905430""(cellular response to glycine)|go:""GO:1905477""(positive regulation of protein localization to membrane)|go:""GO:1905664""(regulation of calcium ion import across plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|interpro:IPR047924|interpro:IPR050198|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|rcsb pdb:7A2J|rcsb pdb:7A2K|rcsb pdb:7A2L|rcsb pdb:7A2M|rcsb pdb:7A2N|rcsb pdb:7A2O|rcsb pdb:7A2P|rcsb pdb:7A2Q|rcsb pdb:7A2R|rcsb pdb:7A2S|rcsb pdb:7A2T|rcsb pdb:7A2U|rcsb pdb:7A2V|rcsb pdb:7A2W|rcsb pdb:7A2X|rcsb pdb:7A2Y|rcsb pdb:7A2Z|rcsb pdb:7UD6|rcsb pdb:8KDX|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9680350|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9856530|dip:DIP-33876N|panther:PTHR24418(orthology-group)"	-	-	-	figure legend:fig.3 table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/12/02	2025/03/10	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	intact-crc:D0145B5398D7E9AD|rigid:+QhjIMUSVILY+O/ld9eT4FmaYLM	false	green fluorescent protein tag:n-n	beta gal tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q2GHU2	uniprotkb:P17706	intact:EBI-26585631	intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955|ensembl:ENSP00000311857.3	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26587400|imex:IM-28642-13	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q2GHU2	"ensembl:ENSG00000175354.20(gene)|ensembl:ENST00000309660.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031904""(endosome lumen)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042532""(negative regulation of tyrosine phosphorylation of STAT protein)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0045650""(negative regulation of macrophage differentiation)|go:""GO:0045722""(positive regulation of gluconeogenesis)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050922""(negative regulation of chemotaxis)|go:""GO:0060334""(regulation of type II interferon-mediated signaling pathway)|go:""GO:0060336""(negative regulation of type II interferon-mediated signaling pathway)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0070104""(negative regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902206""(negative regulation of interleukin-2-mediated signaling pathway)|go:""GO:1902215""(negative regulation of interleukin-4-mediated signaling pathway)|go:""GO:1902227""(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:""GO:1902233""(negative regulation of positive thymic T cell selection)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903899""(positive regulation of PERK-mediated unfolded protein response)|go:""GO:2000587""(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P17706|rcsb pdb:1L8K|rcsb pdb:6ZZ4|rcsb pdb:7F5N|rcsb pdb:7F5O|rcsb pdb:7UAD|rcsb pdb:8U0H|rcsb pdb:8UH6|rcsb pdb:9C54|rcsb pdb:9C55|rcsb pdb:9C56|reactome:R-HSA-6807004|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-9833482|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1|efo:""Orphanet:85408""|efo:""Orphanet:85410""|panther:PTHR46047(orthology-group)"	-	-	-	figure legend:fig.3 table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/12/02	2024/11/14	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606	intact-crc:368601A5BD4B77E3|rigid:L5PqbWQrn3ch28GQ2OVgeTrB6vg	false	green fluorescent protein tag:n-n	beta gal tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P06241	uniprotkb:Q2GHU2	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671.3|ensembl:ENSP00000357656.2	intact:EBI-26585631	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26595542|imex:IM-28642-15	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|ensembl:ENSG00000010810.18(gene)|ensembl:ENST00000354650.7(transcript)|ensembl:ENST00000368667.6(transcript)|go:""GO:0000304""(response to singlet oxygen)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001764""(neuron migration)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0003015""(heart process)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007216""(G protein-coupled glutamate receptor signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0007612""(learning)|go:""GO:0007631""(feeding behavior)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010467""(gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010730""(negative regulation of hydrogen peroxide biosynthetic process)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030425""(dendrite)|go:""GO:0030900""(forebrain development)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031802""(type 5 metabotropic glutamate receptor binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0038026""(reelin-mediated signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0043204""(perikaryon)|go:""GO:0043274""(phospholipase binding)|go:""GO:0044297""(cell body)|go:""GO:0044325""(transmembrane transporter binding)|interpro:IPR035750|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045471""(response to ethanol)|go:""GO:0046872""(metal ion binding)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050798""(activated T cell proliferation)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050900""(leukocyte migration)|go:""GO:0050966""(detection of mechanical stimulus involved in sensory perception of pain)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070851""(growth factor receptor binding)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097386""(glial cell projection)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1900449""(regulation of glutamate receptor signaling pathway)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902951""(negative regulation of dendritic spine maintenance)|go:""GO:1904645""(response to amyloid-beta)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:1905430""(cellular response to glycine)|go:""GO:1905477""(positive regulation of protein localization to membrane)|go:""GO:1905664""(regulation of calcium ion import across plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|interpro:IPR047924|interpro:IPR050198|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|rcsb pdb:7A2J|rcsb pdb:7A2K|rcsb pdb:7A2L|rcsb pdb:7A2M|rcsb pdb:7A2N|rcsb pdb:7A2O|rcsb pdb:7A2P|rcsb pdb:7A2Q|rcsb pdb:7A2R|rcsb pdb:7A2S|rcsb pdb:7A2T|rcsb pdb:7A2U|rcsb pdb:7A2V|rcsb pdb:7A2W|rcsb pdb:7A2X|rcsb pdb:7A2Y|rcsb pdb:7A2Z|rcsb pdb:7UD6|rcsb pdb:8KDX|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9680350|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9856530|dip:DIP-33876N|panther:PTHR24418(orthology-group)"	mint:Q2GHU2	-	-	-	figure legend:fig.4a,5a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/12/02	2025/03/10	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:25F41F62CFDB8353|rigid:+QhjIMUSVILY+O/ld9eT4FmaYLM	false	-	green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:1200""(immunocytochemistry)"	"psi-mi:""MI:1200""(immunocytochemistry)"
uniprotkb:P17706	uniprotkb:Q2GHU2	intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955|ensembl:ENSP00000311857.3	intact:EBI-26585631	psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26595553|imex:IM-28642-17	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000175354.20(gene)|ensembl:ENST00000309660.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031904""(endosome lumen)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042532""(negative regulation of tyrosine phosphorylation of STAT protein)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0045650""(negative regulation of macrophage differentiation)|go:""GO:0045722""(positive regulation of gluconeogenesis)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050922""(negative regulation of chemotaxis)|go:""GO:0060334""(regulation of type II interferon-mediated signaling pathway)|go:""GO:0060336""(negative regulation of type II interferon-mediated signaling pathway)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0070104""(negative regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902206""(negative regulation of interleukin-2-mediated signaling pathway)|go:""GO:1902215""(negative regulation of interleukin-4-mediated signaling pathway)|go:""GO:1902227""(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:""GO:1902233""(negative regulation of positive thymic T cell selection)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903899""(positive regulation of PERK-mediated unfolded protein response)|go:""GO:2000587""(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P17706|rcsb pdb:1L8K|rcsb pdb:6ZZ4|rcsb pdb:7F5N|rcsb pdb:7F5O|rcsb pdb:7UAD|rcsb pdb:8U0H|rcsb pdb:8UH6|rcsb pdb:9C54|rcsb pdb:9C55|rcsb pdb:9C56|reactome:R-HSA-6807004|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-9833482|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1|efo:""Orphanet:85408""|efo:""Orphanet:85410""|panther:PTHR46047(orthology-group)"	mint:Q2GHU2	-	-	-	figure legend:fig.4b,5b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/12/02	2024/11/14	rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:8DCF4CFD66EAFBD4|rigid:L5PqbWQrn3ch28GQ2OVgeTrB6vg	false	-	green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:1200""(immunocytochemistry)"	"psi-mi:""MI:1200""(immunocytochemistry)"
uniprotkb:Q01518	uniprotkb:Q2GHU2	intact:EBI-2808398|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1|ensembl:ENSP00000361878.2|ensembl:ENSP00000361883.3|ensembl:ENSP00000361891.3	intact:EBI-26585631	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26595559|imex:IM-28642-19	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_005270425.1|ensembl:ENSG00000131236.18(gene)|ensembl:ENST00000372792.7(transcript)|ensembl:ENST00000372797.7(transcript)|ensembl:ENST00000372805.8(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001667""(ameboidal-type cell migration)|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007165""(signal transduction)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0019933""(cAMP-mediated signaling)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098885""(modification of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR036222|interpro:IPR036223|interpro:IPR053950|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|dip:DIP-62063N|panther:PTHR10652(orthology-group)"	mint:Q2GHU2	-	crc64:7789D1FAC0D1AB7B	-	figure legend:fig.4c,5c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/12/02	2025/02/28	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:962422505B3589D9|rigid:DM4aYs0zj2G6zQ86nJmc3S9Mz5I	false	-	green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:1200""(immunocytochemistry)"	"psi-mi:""MI:1200""(immunocytochemistry)"
uniprotkb:Q01518	uniprotkb:Q2GHU2	intact:EBI-2808398|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1|ensembl:ENSP00000361878.2|ensembl:ENSP00000361883.3|ensembl:ENSP00000361891.3	intact:EBI-26585631	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26595595|imex:IM-28642-27	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_005270425.1|ensembl:ENSG00000131236.18(gene)|ensembl:ENST00000372792.7(transcript)|ensembl:ENST00000372797.7(transcript)|ensembl:ENST00000372805.8(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001667""(ameboidal-type cell migration)|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007165""(signal transduction)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0019933""(cAMP-mediated signaling)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098885""(modification of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR036222|interpro:IPR036223|interpro:IPR053950|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|dip:DIP-62063N|panther:PTHR10652(orthology-group)"	mint:Q2GHU2	-	crc64:7789D1FAC0D1AB7B	-	figure legend:fig.6j-l,7c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens THP-1 acute monocytic leukemia cell)	-	2020/12/02	2025/02/28	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:9D0BEF2A2CFF3792|rigid:DM4aYs0zj2G6zQ86nJmc3S9Mz5I	false	-	-	-	-	"psi-mi:""MI:1200""(immunocytochemistry)"	"psi-mi:""MI:1200""(immunocytochemistry)"
uniprotkb:P17706	uniprotkb:Q2GHU2	intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955|ensembl:ENSP00000311857.3	intact:EBI-26585631	psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26595608|imex:IM-28642-29	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000175354.20(gene)|ensembl:ENST00000309660.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031904""(endosome lumen)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042532""(negative regulation of tyrosine phosphorylation of STAT protein)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0045650""(negative regulation of macrophage differentiation)|go:""GO:0045722""(positive regulation of gluconeogenesis)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050922""(negative regulation of chemotaxis)|go:""GO:0060334""(regulation of type II interferon-mediated signaling pathway)|go:""GO:0060336""(negative regulation of type II interferon-mediated signaling pathway)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0070104""(negative regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902206""(negative regulation of interleukin-2-mediated signaling pathway)|go:""GO:1902215""(negative regulation of interleukin-4-mediated signaling pathway)|go:""GO:1902227""(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:""GO:1902233""(negative regulation of positive thymic T cell selection)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903899""(positive regulation of PERK-mediated unfolded protein response)|go:""GO:2000587""(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P17706|rcsb pdb:1L8K|rcsb pdb:6ZZ4|rcsb pdb:7F5N|rcsb pdb:7F5O|rcsb pdb:7UAD|rcsb pdb:8U0H|rcsb pdb:8UH6|rcsb pdb:9C54|rcsb pdb:9C55|rcsb pdb:9C56|reactome:R-HSA-6807004|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-9833482|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1|efo:""Orphanet:85408""|efo:""Orphanet:85410""|panther:PTHR46047(orthology-group)"	mint:Q2GHU2	-	-	-	figure legend:fig.6g-i, 7b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens THP-1 acute monocytic leukemia cell)	-	2020/12/02	2024/11/14	rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:3AD765BAC160BF9F|rigid:L5PqbWQrn3ch28GQ2OVgeTrB6vg	false	-	-	-	-	"psi-mi:""MI:1200""(immunocytochemistry)"	"psi-mi:""MI:1200""(immunocytochemistry)"
uniprotkb:P06241	uniprotkb:Q2GHU2	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671.3|ensembl:ENSP00000357656.2	intact:EBI-26585631	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26595614|imex:IM-28642-31	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|ensembl:ENSG00000010810.18(gene)|ensembl:ENST00000354650.7(transcript)|ensembl:ENST00000368667.6(transcript)|go:""GO:0000304""(response to singlet oxygen)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001764""(neuron migration)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0003015""(heart process)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007216""(G protein-coupled glutamate receptor signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0007612""(learning)|go:""GO:0007631""(feeding behavior)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010467""(gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010730""(negative regulation of hydrogen peroxide biosynthetic process)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030425""(dendrite)|go:""GO:0030900""(forebrain development)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031802""(type 5 metabotropic glutamate receptor binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0038026""(reelin-mediated signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0043204""(perikaryon)|go:""GO:0043274""(phospholipase binding)|go:""GO:0044297""(cell body)|go:""GO:0044325""(transmembrane transporter binding)|interpro:IPR035750|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045471""(response to ethanol)|go:""GO:0046872""(metal ion binding)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050798""(activated T cell proliferation)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050900""(leukocyte migration)|go:""GO:0050966""(detection of mechanical stimulus involved in sensory perception of pain)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070851""(growth factor receptor binding)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097386""(glial cell projection)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1900449""(regulation of glutamate receptor signaling pathway)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902951""(negative regulation of dendritic spine maintenance)|go:""GO:1904645""(response to amyloid-beta)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:1905430""(cellular response to glycine)|go:""GO:1905477""(positive regulation of protein localization to membrane)|go:""GO:1905664""(regulation of calcium ion import across plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|interpro:IPR047924|interpro:IPR050198|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|rcsb pdb:7A2J|rcsb pdb:7A2K|rcsb pdb:7A2L|rcsb pdb:7A2M|rcsb pdb:7A2N|rcsb pdb:7A2O|rcsb pdb:7A2P|rcsb pdb:7A2Q|rcsb pdb:7A2R|rcsb pdb:7A2S|rcsb pdb:7A2T|rcsb pdb:7A2U|rcsb pdb:7A2V|rcsb pdb:7A2W|rcsb pdb:7A2X|rcsb pdb:7A2Y|rcsb pdb:7A2Z|rcsb pdb:7UD6|rcsb pdb:8KDX|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9680350|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9856530|dip:DIP-33876N|panther:PTHR24418(orthology-group)"	mint:Q2GHU2	-	-	-	figure legend:fig.6d-f, 7a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens THP-1 acute monocytic leukemia cell)	-	2020/12/02	2025/03/10	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:615F739A63160EB5|rigid:+QhjIMUSVILY+O/ld9eT4FmaYLM	false	-	-	-	-	"psi-mi:""MI:1200""(immunocytochemistry)"	"psi-mi:""MI:1200""(immunocytochemistry)"
uniprotkb:Q86SE9	uniprotkb:Q2GHU2	intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500.5|ensembl:ENSP00000445704.1|ensembl:ENSP00000479492.1	intact:EBI-26585631	psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26595618|imex:IM-28642-33	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|ensembl:ENSG00000180628.15(gene)|ensembl:ENST00000336126.6(transcript)|ensembl:ENST00000543648.5(transcript)|ensembl:ENST00000614189.4(transcript)|go:""GO:0000805""(X chromosome)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0140862""(histone H2AK119 ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR051507|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|panther:PTHR45893(orthology-group)"	mint:Q2GHU2	-	-	-	figure legend:fig.6a-c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens THP-1 acute monocytic leukemia cell)	-	2020/12/02	2025/01/27	rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	intact-crc:0BCDD51CA1B00D67|rigid:A0H/eTxEptyOTe9UuwWFLhqEkvQ	false	-	-	-	-	"psi-mi:""MI:1200""(immunocytochemistry)"	"psi-mi:""MI:1200""(immunocytochemistry)"
uniprotkb:Q2GL86	uniprotkb:P07237	intact:EBI-26435798	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801.4	psi-mi:q2gl86_anapz(display_long)|uniprotkb:APH_0248(locus name)	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Green et al. (2020)	pubmed:31992623|imex:IM-28466	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435803|imex:IM-28466-1	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_011450388.1|mint:Q2GL86	"panther:PTHR18929(orthology-group)|ensembl:ENSG00000185624.16(gene)|ensembl:ENST00000331483.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0003779""(actin binding)|go:""GO:0004656""(procollagen-proline 4-dioxygenase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0016222""(procollagen-proline 4-dioxygenase complex)|go:""GO:0016972""(thiol oxidase activity)|go:""GO:0018401""(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:""GO:0019899""(enzyme binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030070""(insulin processing)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035722""(interleukin-12-mediated signaling pathway)|go:""GO:0038155""(interleukin-23-mediated signaling pathway)|go:""GO:0042470""(melanosome)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902175""(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|rcsb pdb:7ZSC|rcsb pdb:8EOJ|rcsb pdb:8GDY|reactome:R-HSA-1650814|reactome:R-HSA-264876|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8964041|reactome:R-HSA-9020591|reactome:R-HSA-9020933|refseq:NP_000909.2|efo:""Orphanet:2050""|efo:""Orphanet:216796""|dip:DIP-32979N"	-	-	-	figure legend:f1a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/24	rogid:5GJtPfOT8FV2sm0NkPlURGCY7Ok212042	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	intact-crc:BC5189AA99C2A53A|rigid:05XD3SyFwanOz3LRrP85aOD4Z3I	false	green fluorescent protein tag:?-?|necessary binding region:113-124	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P07237	uniprotkb:Q2GL86	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801.4	intact:EBI-26435798	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	psi-mi:q2gl86_anapz(display_long)|uniprotkb:APH_0248(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Green et al. (2020)	pubmed:31992623|imex:IM-28466	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435814|imex:IM-28466-3	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR18929(orthology-group)|ensembl:ENSG00000185624.16(gene)|ensembl:ENST00000331483.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0003779""(actin binding)|go:""GO:0004656""(procollagen-proline 4-dioxygenase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0016222""(procollagen-proline 4-dioxygenase complex)|go:""GO:0016972""(thiol oxidase activity)|go:""GO:0018401""(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:""GO:0019899""(enzyme binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030070""(insulin processing)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035722""(interleukin-12-mediated signaling pathway)|go:""GO:0038155""(interleukin-23-mediated signaling pathway)|go:""GO:0042470""(melanosome)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902175""(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|rcsb pdb:7ZSC|rcsb pdb:8EOJ|rcsb pdb:8GDY|reactome:R-HSA-1650814|reactome:R-HSA-264876|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8964041|reactome:R-HSA-9020591|reactome:R-HSA-9020933|refseq:NP_000909.2|efo:""Orphanet:2050""|efo:""Orphanet:216796""|dip:DIP-32979N"	refseq:WP_011450388.1|mint:Q2GL86	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/30	2025/03/24	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	rogid:5GJtPfOT8FV2sm0NkPlURGCY7Ok212042	intact-crc:FC86330F8BF5A7B6|rigid:05XD3SyFwanOz3LRrP85aOD4Z3I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43865	uniprotkb:Q2GL86	intact:EBI-2371423|uniprotkb:Q2TAJ6|uniprotkb:Q502W8|uniprotkb:Q5VSM0|uniprotkb:Q6P171|uniprotkb:Q96PK4|uniprotkb:Q9UG84|ensembl:ENSP00000358814.5|uniprotkb:B4E168	intact:EBI-26435798	"psi-mi:sahh2_human(display_long)|uniprotkb:AHCYL1(gene name)|psi-mi:AHCYL1(display_short)|uniprotkb:DCAL(gene name synonym)|uniprotkb:XPVKONA(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 2(gene name synonym)|uniprotkb:DC-expressed AHCY-like molecule(gene name synonym)|uniprotkb:Putative adenosylhomocysteinase 2(gene name synonym)|uniprotkb:""IP(3)Rs binding protein released with IP(3)""(gene name synonym)|uniprotkb:IRBIT(gene name synonym)"	psi-mi:q2gl86_anapz(display_long)|uniprotkb:APH_0248(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Green et al. (2020)	pubmed:31992623|imex:IM-28466	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435878|imex:IM-28466-5	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168710.18(gene)|ensembl:ENST00000369799.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0010765""(positive regulation of sodium ion transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0031440""(regulation of mRNA 3'-end processing)|go:""GO:0032412""(regulation of monoatomic ion transmembrane transporter activity)|go:""GO:0033353""(S-adenosylmethionine cycle)|go:""GO:0038166""(angiotensin-activated signaling pathway)|go:""GO:0042045""(epithelial fluid transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0044070""(regulation of monoatomic anion transport)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:O43865|rcsb pdb:3MTG|reactome:R-HSA-112043|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|refseq:NP_001229602.1|refseq:NP_001229603.1|refseq:NP_001229604.1|refseq:NP_001229605.1|refseq:NP_006612.2|panther:PTHR23420(orthology-group)"	refseq:WP_011450388.1|mint:Q2GL86	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/30	2024/11/14	rogid:uwZ+P9SdKadoVn01p/b8qHp6egk9606	rogid:5GJtPfOT8FV2sm0NkPlURGCY7Ok212042	intact-crc:EF5594AE12C1A5FD|rigid:NlVa/Yk4sZu+KujygrTuI0hzHx4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6K9	uniprotkb:Q2GL86	intact:EBI-81279|ensembl:ENSP00000390368.3|ensembl:ENSP00000394934.2|ensembl:ENSP00000395205.2|ensembl:ENSP00000471166.1|ensembl:ENSP00000479662.1|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1	intact:EBI-26435798	psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym)	psi-mi:q2gl86_anapz(display_long)|uniprotkb:APH_0248(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Green et al. (2020)	pubmed:31992623|imex:IM-28466	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435882|imex:IM-28466-7	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000269335.7(gene)|ensembl:ENST00000422680.6(transcript)|ensembl:ENST00000440286.6(transcript)|ensembl:ENST00000445622.6(transcript)|ensembl:ENST00000594239.6(transcript)|ensembl:ENST00000611071.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000922""(spindle pole)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0006974""(DNA damage response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008385""(IkappaB kinase complex)|go:""GO:0009615""(response to virus)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043276""(anoikis)|go:""GO:0045087""(innate immune response)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0072686""(mitotic spindle)|go:""GO:1990450""(linear polyubiquitin binding)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|interpro:IPR051301|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6XX0|rcsb pdb:6YEK|rcsb pdb:7T2U|rcsb pdb:7TV4|rcsb pdb:9AZJ|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9705671|reactome:R-HSA-975144|reactome:R-HSA-9758274|reactome:R-HSA-9833482|reactome:R-HSA-9860276|reactome:R-HSA-9860927|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_003630.1|panther:PTHR31553(orthology-group)|efo:""Orphanet:319612""|efo:""Orphanet:464""|efo:""Orphanet:69088""|efo:""Orphanet:98813""|dip:DIP-27528N"	refseq:WP_011450388.1|mint:Q2GL86	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/30	2025/03/26	rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606	rogid:5GJtPfOT8FV2sm0NkPlURGCY7Ok212042	intact-crc:9B3C935A67C90855|rigid:Gdk988WtwlqPfrr9m6soCK2Gj8A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75807	uniprotkb:Q2GL86	intact:EBI-714746|uniprotkb:Q6IA96|uniprotkb:Q9NVU6|intact:EBI-28977765|ensembl:ENSP00000200453.4|uniprotkb:B4DKQ3	intact:EBI-26435798	psi-mi:pr15a_human(display_long)|uniprotkb:Myeloid differentiation primary response protein MyD116 homolog(gene name synonym)|uniprotkb:PPP1R15A(gene name)|psi-mi:PPP1R15A(display_short)|uniprotkb:GADD34(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD34(gene name synonym)	psi-mi:q2gl86_anapz(display_long)|uniprotkb:APH_0248(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Green et al. (2020)	pubmed:31992623|imex:IM-28466	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435886|imex:IM-28466-9	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055145.3|ensembl:ENSG00000087074.9(gene)|ensembl:ENST00000200453.6(transcript)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0016020""(membrane)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0032058""(positive regulation of translational initiation in response to stress)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0043558""(regulation of translational initiation in response to stress)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|interpro:IPR019523|interpro:IPR051254|mint:O75807|rcsb pdb:4XPN|rcsb pdb:7NXV|rcsb pdb:7NZM|rcsb pdb:8QZZ|reactome:R-HSA-2173788|reactome:R-HSA-9648895|panther:PTHR16489(orthology-group)"	refseq:WP_011450388.1|mint:Q2GL86	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/30	2024/11/14	rogid:2pmlIgM2OX5qK5Bvb1p9x9ZERLw9606	rogid:5GJtPfOT8FV2sm0NkPlURGCY7Ok212042	intact-crc:ADE0C27848A7A57A|rigid:wJhs4XjQZu+y1YEJGFzTtFYrBwg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P12956	uniprotkb:Q2GL86	intact:EBI-353208|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|ensembl:ENSP00000352257.4|ensembl:ENSP00000353192.3|ensembl:ENSP00000384257.1|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8|intact:EBI-21355587	intact:EBI-26435798	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:q2gl86_anapz(display_long)|uniprotkb:APH_0248(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Green et al. (2020)	pubmed:31992623|imex:IM-28466	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435893|imex:IM-28466-11	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001460.1|refseq:NP_001275905.1|ensembl:ENSG00000196419.13(gene)|ensembl:ENST00000359308.8(transcript)|ensembl:ENST00000360079.8(transcript)|ensembl:ENST00000405878.5(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000725""(recombinational repair)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000783""(nuclear telomere cap complex)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006266""(obsolete DNA ligation)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030332""(cyclin binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0043564""(""Ku70:Ku80 complex"")|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045621""(positive regulation of lymphocyte differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0051575""(5'-deoxyribose-5-phosphate lyase activity)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0071475""(cellular hyperosmotic salinity response)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097680""(double-strand break repair via classical nonhomologous end joining)|rcsb pdb:8ASC|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|interpro:IPR047087|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7Z6O|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:7ZT6|rcsb pdb:7ZVT|rcsb pdb:7ZWA|rcsb pdb:7ZYG|rcsb pdb:8AG4|rcsb pdb:8AG5|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|refseq:NP_001275906.1|dip:DIP-24188N|panther:PTHR12604(orthology-group)"	refseq:WP_011450388.1|mint:Q2GL86	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/30	2025/02/20	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rogid:5GJtPfOT8FV2sm0NkPlURGCY7Ok212042	intact-crc:5DF046E10BF3EDBA|rigid:zpWyCH5GqOPxoSIXsISRTViuDQY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UJ78	uniprotkb:Q2GL86	intact:EBI-7228860|uniprotkb:Q5T6E1|uniprotkb:B2R6V1|uniprotkb:Q5T6E4|uniprotkb:Q9UBW0|intact:MINT-1188987|intact:MINT-4714895|uniprotkb:Q9NZY5|uniprotkb:Q5T6E2|uniprotkb:Q9UJ77|uniprotkb:Q96IY6|intact:EBI-28970275|ensembl:ENSP00000337034.4	intact:EBI-26435798	psi-mi:zmym5_human(display_long)|uniprotkb:ZMYM5(gene name)|psi-mi:ZMYM5(display_short)|uniprotkb:ZNF198L1(gene name synonym)|uniprotkb:ZNF237(gene name synonym)|uniprotkb:Zinc finger protein 198-like 1(gene name synonym)|uniprotkb:Zinc finger protein 237(gene name synonym)|uniprotkb:HSPC050(orf name)	psi-mi:q2gl86_anapz(display_long)|uniprotkb:APH_0248(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Green et al. (2020)	pubmed:31992623|imex:IM-28466	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435900|imex:IM-28466-13	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001034738.1|refseq:NP_001136156.1|uniprotkb:Q5T6E3(q5t6e3_human)|refseq:NP_001034739.1|refseq:XP_005266650.1|refseq:XP_005266651.1|refseq:XP_006719957.1|ensembl:ENSG00000132950.19(gene)|ensembl:ENST00000337963.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0005634""(nucleus)|go:""GO:0008270""(zinc ion binding)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR051284|mint:Q9UJ78|rcsb pdb:2DAS|panther:PTHR45736(orthology-group)"	refseq:WP_011450388.1|mint:Q2GL86	-	comment:mint|comment:homomint	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/10/30	2024/11/14	rogid:ZujAso8yp2Fu1WlvlR3G5vwOYaE9606	rogid:5GJtPfOT8FV2sm0NkPlURGCY7Ok212042	intact-crc:2AF6F4BEA41E1A09|rigid:s3DJC6dna+OGS3/GlVXIxTiiSSk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q2GL86	uniprotkb:P07237	intact:EBI-26435798	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801.4	psi-mi:q2gl86_anapz(display_long)|uniprotkb:APH_0248(locus name)	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Green et al. (2020)	pubmed:31992623|imex:IM-28466	"taxid:212042(anapz)|taxid:212042(""Anaplasma phagocytophilum (strain HZ)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26435970|imex:IM-28466-17	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_011450388.1|mint:Q2GL86	"panther:PTHR18929(orthology-group)|ensembl:ENSG00000185624.16(gene)|ensembl:ENST00000331483.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0003779""(actin binding)|go:""GO:0004656""(procollagen-proline 4-dioxygenase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0016222""(procollagen-proline 4-dioxygenase complex)|go:""GO:0016972""(thiol oxidase activity)|go:""GO:0018401""(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:""GO:0019899""(enzyme binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030070""(insulin processing)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035722""(interleukin-12-mediated signaling pathway)|go:""GO:0038155""(interleukin-23-mediated signaling pathway)|go:""GO:0042470""(melanosome)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902175""(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|rcsb pdb:7ZSC|rcsb pdb:8EOJ|rcsb pdb:8GDY|reactome:R-HSA-1650814|reactome:R-HSA-264876|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8964041|reactome:R-HSA-9020591|reactome:R-HSA-9020933|refseq:NP_000909.2|efo:""Orphanet:2050""|efo:""Orphanet:216796""|dip:DIP-32979N"	-	-	-	figure legend:f7a F7b F8a F8b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/10/30	2025/03/24	rogid:5GJtPfOT8FV2sm0NkPlURGCY7Ok212042	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	intact-crc:F70208F7F5F0FAFE|rigid:05XD3SyFwanOz3LRrP85aOD4Z3I	false	green fluorescent protein tag:?-?|mutation with no effect:117-117|mutation with no effect:116-116|mutation with no effect:121-121|mutation decreasing interaction strength:118-118|mutation decreasing interaction strength:122-122|mutation decreasing interaction strength:119-119|mutation decreasing interaction strength:120-120|mutation decreasing interaction strength:122-122|mutation decreasing interaction strength:122-122|mutation decreasing interaction strength:123-123|mutation with no effect:123-123|mutation with no effect:123-123|mutation decreasing interaction strength:124-124|mutation with no effect:124-124|mutation decreasing interaction strength:124-124	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q7VLE8	uniprotkb:P41240	intact:EBI-26445163	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003.9|ensembl:ENSP00000414764.2|ensembl:ENSP00000454906.1	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.59	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653.17(gene)|ensembl:ENST00000220003.14(transcript)|ensembl:ENST00000439220.6(transcript)|ensembl:ENST00000567571.5(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010989""(negative regulation of low-density lipoprotein particle clearance)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0042997""(negative regulation of Golgi to plasma membrane protein transport)|go:""GO:0045779""(negative regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369|panther:PTHR24418(orthology-group)|refseq:NP_001120662.1|refseq:NP_004374.1"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q7VLE8	uniprotkb:O43639	intact:EBI-26445163	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|uniprotkb:D3DVK1|ensembl:ENSP00000233154.4|ensembl:ENSP00000377018.2	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051.14(gene)|ensembl:ENST00000233154.9(transcript)|ensembl:ENST00000393349.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0007015""(actin filament organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007172""(signal complex assembly)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016477""(cell migration)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036493""(positive regulation of translation in response to endoplasmic reticulum stress)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0060996""(dendritic spine development)|go:""GO:0097110""(scaffold protein binding)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|interpro:IPR051184|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1|panther:PTHR19969(orthology-group)|ensembl:ENSP00000233154.4|ensembl:ENSP00000377018.2"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q7VLE8	uniprotkb:P16333	intact:EBI-26445163	intact:EBI-389883|uniprotkb:B7Z751|intact:EBI-3448658|uniprotkb:D3DNE3|ensembl:ENSP00000288986.2|ensembl:ENSP00000417273.1	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:Cytoplasmic protein NCK1(gene name synonym)|uniprotkb:NCK adapter protein 1(gene name synonym)|uniprotkb:SH2/SH3 adapter protein NCK-alpha(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"refseq:NP_001177725.1|refseq:NP_006144.1|refseq:NP_001278928.1|ensembl:ENSG00000158092.7(gene)|ensembl:ENST00000288986.6(transcript)|ensembl:ENST00000481752.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007015""(actin filament organization)|go:""GO:0007172""(signal complex assembly)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036493""(positive regulation of translation in response to endoplasmic reticulum stress)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0071074""(eukaryotic initiation factor eIF2 binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903676""(positive regulation of cap-dependent translational initiation)|go:""GO:1903679""(positive regulation of cap-independent translational initiation)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1903912""(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|interpro:IPR051184|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-9833482|reactome:R-HSA-983695|dip:DIP-639N|panther:PTHR19969(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q7VLE8	uniprotkb:Q06124	intact:EBI-26445163	intact:EBI-297779|uniprotkb:Q96HD7|uniprotkb:A8K1D9|ensembl:ENSP00000340944.3|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"efo:""Orphanet:2499""|efo:""Orphanet:500""|efo:""Orphanet:648""|efo:""Orphanet:86834""|ensembl:ENSG00000179295.19(gene)|ensembl:ENST00000351677.7(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007409""(axonogenesis)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0009755""(hormone-mediated signaling pathway)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021697""(cerebellar cortex formation)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030220""(platelet formation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031666""(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0032528""(microvillus organization)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0033629""(negative regulation of cell adhesion mediated by integrin)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035265""(organ growth)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0036302""(atrioventricular canal development)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0042445""(hormone metabolic process)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0045296""(cadherin binding)|go:""GO:0045778""(positive regulation of ossification)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0046676""(negative regulation of insulin secretion)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0046887""(positive regulation of hormone secretion)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048011""(neurotrophin TRK receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048806""(genitalia development)|go:""GO:0048839""(inner ear development)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051428""(peptide hormone receptor binding)|go:""GO:0051463""(negative regulation of cortisol secretion)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060125""(negative regulation of growth hormone secretion)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0061582""(intestinal epithelial cell migration)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:Q06124|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|rcsb pdb:4DGP|rcsb pdb:4DGX|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|rcsb pdb:5EHR|rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|rcsb pdb:7R75|rcsb pdb:7R7D|rcsb pdb:7R7I|rcsb pdb:7R7L|rcsb pdb:7RCT|rcsb pdb:7TVJ|rcsb pdb:7VXG|rcsb pdb:7XHQ|rcsb pdb:8B5Y|rcsb pdb:8CBH|rcsb pdb:8GWW|rcsb pdb:8RZW|rcsb pdb:8RZY|rcsb pdb:8S01|rcsb pdb:8S04|rcsb pdb:8S06|rcsb pdb:8S07|rcsb pdb:8S0H|rcsb pdb:8S0I|rcsb pdb:8S0J|rcsb pdb:8S0K|rcsb pdb:8S0O|rcsb pdb:8S0P|rcsb pdb:8S0Q|rcsb pdb:8S0S|rcsb pdb:8T6D|rcsb pdb:8T6G|rcsb pdb:8T7Q|rcsb pdb:8T8Q|rcsb pdb:8U7W|rcsb pdb:8U7X|rcsb pdb:8WFY|rcsb pdb:8WX7|rcsb pdb:9BLG|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6811558|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-9028731|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-936964|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9702518|reactome:R-HSA-9703648|reactome:R-HSA-9705671|refseq:NP_001317366.1|refseq:NP_002825.3|refseq:NP_542168.1|dip:DIP-516N|ensembl:ENSP00000340944.3|ensembl:ENST00000392597.5|ensembl:ENSP00000376376.1|ensembl:ENST00000635625.1|ensembl:ENSP00000489597.1|panther:PTHR46559(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q7VLE8	uniprotkb:P62993	intact:EBI-26445163	intact:EBI-401755|uniprotkb:P29354|uniprotkb:Q14450|uniprotkb:Q63057|uniprotkb:Q63059|ensembl:ENSP00000339007.4|ensembl:ENSP00000376345.1|ensembl:ENSP00000376347.1|ensembl:ENSP00000496913.1	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:grb2_human(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)|uniprotkb:ASH(gene name synonym)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)|uniprotkb:Protein Ash(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"refseq:NP_002077.1|refseq:NP_987102.1|ensembl:ENSG00000177885.15(gene)|ensembl:ENST00000316804.10(transcript)|ensembl:ENST00000392562.5(transcript)|ensembl:ENST00000392564.5(transcript)|ensembl:ENST00000648046.1(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005091""(guanyl-nucleotide exchange factor adaptor activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005168""(neurotrophin TRKA receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014044""(Schwann cell development)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031623""(receptor internalization)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042110""(T cell activation)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042552""(myelination)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060670""(branching involved in labyrinthine layer morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070436""(Grb2-EGFR complex)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|mint:P62993|rcsb pdb:1AZE|rcsb pdb:1BM2|rcsb pdb:1BMB|rcsb pdb:1CJ1|rcsb pdb:1FHS|rcsb pdb:1FYR|rcsb pdb:1GCQ|rcsb pdb:1GFC|rcsb pdb:1GFD|rcsb pdb:1GHU|rcsb pdb:1GRI|rcsb pdb:1IO6|rcsb pdb:1JYQ|rcsb pdb:1JYR|rcsb pdb:1JYU|rcsb pdb:1QG1|rcsb pdb:1TZE|rcsb pdb:1X0N|rcsb pdb:1ZFP|rcsb pdb:2AOA|rcsb pdb:2AOB|rcsb pdb:2H46|rcsb pdb:2H5K|rcsb pdb:2HUW|rcsb pdb:2VVK|rcsb pdb:2VWF|rcsb pdb:2W0Z|rcsb pdb:3C7I|rcsb pdb:3IMD|rcsb pdb:3IMJ|rcsb pdb:3IN7|rcsb pdb:3IN8|rcsb pdb:3KFJ|rcsb pdb:3MXC|rcsb pdb:3MXY|rcsb pdb:3N7Y|rcsb pdb:3N84|rcsb pdb:3N8M|rcsb pdb:3OV1|rcsb pdb:3OVE|rcsb pdb:3S8L|rcsb pdb:3S8N|rcsb pdb:3S8O|rcsb pdb:3WA4|rcsb pdb:4P9V|rcsb pdb:4P9Z|rcsb pdb:5CDW|rcsb pdb:6ICG|rcsb pdb:6ICH|rcsb pdb:6SDF|rcsb pdb:6VK2|rcsb pdb:6WM1|rcsb pdb:6WO2|rcsb pdb:7MPH|rcsb pdb:8DGO|reactome:R-HSA-109704|reactome:R-HSA-112412|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-167044|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2029482|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354194|reactome:R-HSA-375165|reactome:R-HSA-388841|reactome:R-HSA-389359|reactome:R-HSA-391160|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8853659|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8865999|reactome:R-HSA-8875360|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8983432|reactome:R-HSA-9013420|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028335|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9645135|reactome:R-HSA-9664422|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9680350|reactome:R-HSA-9702518|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9725370|reactome:R-HSA-983695|reactome:R-HSA-9842663|dip:DIP-29229N|panther:PTHR46037(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:SLnslQ7NHbnuK06nMVuRvJpoOA49606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q7VLE8	uniprotkb:Q08211	intact:EBI-26445163	intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520.3	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"refseq:NP_001348.2|dip:DIP-31504N|ensembl:ENSG00000135829.17(gene)|ensembl:ENST00000367549.4(transcript)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001069""(regulatory region RNA binding)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005726""(perichromatin fibrils)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010501""(obsolete RNA secondary structure unwinding)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016442""(RISC complex)|go:""GO:0016604""(nuclear body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017111""(ribonucleoside triphosphate phosphatase activity)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0032741""(positive regulation of interleukin-18 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033679""(3'-5' DNA/RNA helicase activity)|go:""GO:0034458""(3'-5' RNA helicase activity)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035197""(siRNA binding)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0039695""(DNA-templated viral transcription)|go:""GO:0043022""(ribosome binding)|go:""GO:0043138""(3'-5' DNA helicase activity)|go:""GO:0044806""(obsolete G-quadruplex DNA unwinding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045142""(triplex DNA binding)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046833""(positive regulation of RNA export from nucleus)|go:""GO:0046872""(metal ion binding)|go:""GO:0047429""(nucleoside triphosphate diphosphatase activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048511""(rhythmic process)|go:""GO:0050434""(positive regulation of viral transcription)|go:""GO:0050684""(regulation of mRNA processing)|go:""GO:0050691""(regulation of defense response to virus by host)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051028""(mRNA transport)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060760""(positive regulation of response to cytokine stimulus)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070578""(RISC-loading complex)|go:""GO:0070922""(RISC complex assembly)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0070937""(CRD-mediated mRNA stability complex)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071360""(cellular response to exogenous dsRNA)|go:""GO:0097165""(nuclear stress granule)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1905172""(RISC complex binding)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|go:""GO:1990825""(sequence-specific mRNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|go:""GO:2000765""(regulation of cytoplasmic translation)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|interpro:IPR048333|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|rcsb pdb:8SZP|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|reactome:R-HSA-9833482|panther:PTHR18934(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q7VLE8	uniprotkb:P62266	intact:EBI-26445163	intact:EBI-353072|uniprotkb:P39028|uniprotkb:Q6IB08|ensembl:ENSP00000296674.8|ensembl:ENSP00000498621.1	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:rs23_human(display_long)|uniprotkb:RPS23(gene name)|psi-mi:RPS23(display_short)|uniprotkb:40S ribosomal protein S23(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"refseq:NP_001016.1|ensembl:ENSG00000186468.13(gene)|ensembl:ENST00000296674.13(transcript)|ensembl:ENST00000651545.1(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0006412""(translation)|go:""GO:0016020""(membrane)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0032040""(small-subunit processome)|go:""GO:0034063""(stress granule assembly)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0045202""(synapse)|go:""GO:1990145""(maintenance of translational fidelity)|interpro:IPR005680(Ribosomal protein S23, eukaryotic/archaeal)|interpro:IPR006032(Ribosomal protein S12/S23)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P62266|rcsb pdb:4CXG|rcsb pdb:4CXH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7WTS|rcsb pdb:7WTT|rcsb pdb:7WTU|rcsb pdb:7WTV|rcsb pdb:7WTW|rcsb pdb:7WTX|rcsb pdb:7WTZ|rcsb pdb:7WU0|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9629569|reactome:R-HSA-9633012|reactome:R-HSA-9735869|reactome:R-HSA-9754678|reactome:R-HSA-975956|reactome:R-HSA-975957|panther:PTHR11652(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:MWZPvSL/G45ocaxA5AXKCkDQxNU9606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q7VLE8	uniprotkb:P23246	intact:EBI-26445163	intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748.5	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"efo:""Orphanet:319308""|ensembl:ENSG00000116560.12(gene)|ensembl:ENST00000357214.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0042382""(paraspeckles)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042754""(negative regulation of circadian rhythm)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1902177""(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|rcsb pdb:7PU5|rcsb pdb:7SP0|rcsb pdb:7UJ1|rcsb pdb:7UK1|reactome:R-HSA-8849468|reactome:R-HSA-9635465|refseq:NP_005057.1|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N|panther:PTHR23189(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q7VLE8	uniprotkb:Q15233	intact:EBI-26445163	intact:EBI-350527|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3|ensembl:ENSP00000276079.8|ensembl:ENSP00000362947.1|ensembl:ENSP00000406673.2|ensembl:ENSP00000410299.2|ensembl:ENSP00000415777.2|ensembl:ENSP00000503031.1|ensembl:ENSP00000503233.1|ensembl:ENSP00000504314.1|ensembl:ENSP00000504351.1	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"efo:""Orphanet:319308""|efo:""Orphanet:466791""|ensembl:ENSG00000147140.17(gene)|ensembl:ENST00000276079.13(transcript)|ensembl:ENST00000373841.5(transcript)|ensembl:ENST00000420903.6(transcript)|ensembl:ENST00000450092.6(transcript)|ensembl:ENST00000454976.2(transcript)|ensembl:ENST00000677274.1(transcript)|ensembl:ENST00000677446.1(transcript)|ensembl:ENST00000677612.1(transcript)|ensembl:ENST00000678231.1(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0042382""(paraspeckles)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903377""(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|rcsb pdb:7PU5|refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|dip:DIP-29951N|panther:PTHR23189(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q7VLE8	uniprotkb:O43143	intact:EBI-26445163	intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741.4	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym)|uniprotkb:Splicing factor Prp43(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"refseq:NP_001349.2|ensembl:ENSG00000109606.13(gene)|ensembl:ENST00000336812.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005689""(U12-type spliceosomal complex)|go:""GO:0005730""(nucleolus)|go:""GO:0006397""(mRNA processing)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0008380""(RNA splicing)|go:""GO:0009636""(response to toxic substance)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043279""(response to alkaloid)|go:""GO:0051607""(defense response to virus)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|interpro:IPR048333|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|rcsb pdb:8EJM|rcsb pdb:8RO2|reactome:R-HSA-72163|dip:DIP-38211N|panther:PTHR18934(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q7VLE8	uniprotkb:Q14444	intact:EBI-26445163	intact:EBI-1047080|uniprotkb:Q15074|intact:EBI-1171814|uniprotkb:Q6IMN4|uniprotkb:A6NMY7|uniprotkb:Q6IMN7|uniprotkb:Q9BV09|intact:EBI-2562858|ensembl:ENSP00000340329.4|ensembl:ENSP00000434150.1|intact:EBI-3449178|uniprotkb:D3DR06	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	psi-mi:capr1_human(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445161|imex:IM-28484-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	"ensembl:ENSG00000135387.21(gene)|ensembl:ENST00000341394.9(transcript)|ensembl:ENST00000532820.5(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007416""(synapse assembly)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030425""(dendrite)|go:""GO:0031252""(cell leading edge)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0045202""(synapse)|go:""GO:0048699""(generation of neurons)|go:""GO:0050775""(positive regulation of dendrite morphogenesis)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0106288""(regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|interpro:IPR022070|interpro:IPR028816|interpro:IPR041637|mint:Q14444|rcsb pdb:4WBE|rcsb pdb:4WBP|rcsb pdb:6TA7|rcsb pdb:7XHG|rcsb pdb:8TH7|refseq:NP_005889.3|refseq:NP_976240.1|refseq:XP_016873238.1|efo:""Orphanet:528084""|panther:PTHR22922(orthology-group)"	-	-	-	figure legend:table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2025/03/21	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606	intact-crc:DAC1089CD3B5FE89|rigid:7sWTJjNSCc/Zgvjat4q0Ljuhs+k	false	myc tag:?-?|binding-associated region:2349-2643	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:P41240	uniprotkb:Q7VLE8	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003.9|ensembl:ENSP00000414764.2|ensembl:ENSP00000454906.1	intact:EBI-26445163	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445207|imex:IM-28484-3	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653.17(gene)|ensembl:ENST00000220003.14(transcript)|ensembl:ENST00000439220.6(transcript)|ensembl:ENST00000567571.5(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010989""(negative regulation of low-density lipoprotein particle clearance)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0042997""(negative regulation of Golgi to plasma membrane protein transport)|go:""GO:0045779""(negative regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369|panther:PTHR24418(orthology-group)|refseq:NP_001120662.1|refseq:NP_004374.1"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	-	-	-	figure legend:fig. 3 a-e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2024/11/14	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	intact-crc:1E9FC7DFC2C806E5|rigid:85sxEUympoaby8ljyKHdd5PiS4Q	false	flag tag:?-?|binding-associated region:82..82-171..171	strep tag:?-?|binding-associated region:2469-2545|mutation decreasing interaction:2469-2469,2545-2545	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:O43639	uniprotkb:Q7VLE8	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|uniprotkb:D3DVK1|ensembl:ENSP00000233154.4|ensembl:ENSP00000377018.2	intact:EBI-26445163	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445220|imex:IM-28484-5	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051.14(gene)|ensembl:ENST00000233154.9(transcript)|ensembl:ENST00000393349.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0007015""(actin filament organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007172""(signal complex assembly)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016477""(cell migration)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036493""(positive regulation of translation in response to endoplasmic reticulum stress)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0060996""(dendritic spine development)|go:""GO:0097110""(scaffold protein binding)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|interpro:IPR051184|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1|panther:PTHR19969(orthology-group)|ensembl:ENSP00000233154.4|ensembl:ENSP00000377018.2"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	-	-	-	figure legend:fig. 3b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2024/11/14	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	intact-crc:56A8A0262D94D486|rigid:O220Ng2mBXAvMgIV2Ps6xhe0TsQ	false	flag tag:?-?	strep tag:?-?|binding-associated region:2469-2545|mutation increasing interaction:2469-2469,2545-2545	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P62993	uniprotkb:Q7VLE8	intact:EBI-401755|uniprotkb:P29354|uniprotkb:Q14450|uniprotkb:Q63057|uniprotkb:Q63059|ensembl:ENSP00000339007.4|ensembl:ENSP00000376345.1|ensembl:ENSP00000376347.1|ensembl:ENSP00000496913.1	intact:EBI-26445163	psi-mi:grb2_human(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)|uniprotkb:ASH(gene name synonym)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)|uniprotkb:Protein Ash(gene name synonym)	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445233|imex:IM-28484-7	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002077.1|refseq:NP_987102.1|ensembl:ENSG00000177885.15(gene)|ensembl:ENST00000316804.10(transcript)|ensembl:ENST00000392562.5(transcript)|ensembl:ENST00000392564.5(transcript)|ensembl:ENST00000648046.1(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005091""(guanyl-nucleotide exchange factor adaptor activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005168""(neurotrophin TRKA receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014044""(Schwann cell development)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031623""(receptor internalization)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042110""(T cell activation)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042552""(myelination)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060670""(branching involved in labyrinthine layer morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070436""(Grb2-EGFR complex)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|mint:P62993|rcsb pdb:1AZE|rcsb pdb:1BM2|rcsb pdb:1BMB|rcsb pdb:1CJ1|rcsb pdb:1FHS|rcsb pdb:1FYR|rcsb pdb:1GCQ|rcsb pdb:1GFC|rcsb pdb:1GFD|rcsb pdb:1GHU|rcsb pdb:1GRI|rcsb pdb:1IO6|rcsb pdb:1JYQ|rcsb pdb:1JYR|rcsb pdb:1JYU|rcsb pdb:1QG1|rcsb pdb:1TZE|rcsb pdb:1X0N|rcsb pdb:1ZFP|rcsb pdb:2AOA|rcsb pdb:2AOB|rcsb pdb:2H46|rcsb pdb:2H5K|rcsb pdb:2HUW|rcsb pdb:2VVK|rcsb pdb:2VWF|rcsb pdb:2W0Z|rcsb pdb:3C7I|rcsb pdb:3IMD|rcsb pdb:3IMJ|rcsb pdb:3IN7|rcsb pdb:3IN8|rcsb pdb:3KFJ|rcsb pdb:3MXC|rcsb pdb:3MXY|rcsb pdb:3N7Y|rcsb pdb:3N84|rcsb pdb:3N8M|rcsb pdb:3OV1|rcsb pdb:3OVE|rcsb pdb:3S8L|rcsb pdb:3S8N|rcsb pdb:3S8O|rcsb pdb:3WA4|rcsb pdb:4P9V|rcsb pdb:4P9Z|rcsb pdb:5CDW|rcsb pdb:6ICG|rcsb pdb:6ICH|rcsb pdb:6SDF|rcsb pdb:6VK2|rcsb pdb:6WM1|rcsb pdb:6WO2|rcsb pdb:7MPH|rcsb pdb:8DGO|reactome:R-HSA-109704|reactome:R-HSA-112412|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-167044|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2029482|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354194|reactome:R-HSA-375165|reactome:R-HSA-388841|reactome:R-HSA-389359|reactome:R-HSA-391160|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8853659|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8865999|reactome:R-HSA-8875360|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8983432|reactome:R-HSA-9013420|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028335|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9645135|reactome:R-HSA-9664422|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9680350|reactome:R-HSA-9702518|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9725370|reactome:R-HSA-983695|reactome:R-HSA-9842663|dip:DIP-29229N|panther:PTHR46037(orthology-group)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	-	-	-	figure legend:fig. 3c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2024/11/14	rogid:SLnslQ7NHbnuK06nMVuRvJpoOA49606	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	intact-crc:FF601895F8242BB8|rigid:qX2HYa6jS8PuqVUU8rQTamhMeIg	false	flag tag:?-?	strep tag:?-?|binding-associated region:2469-2545|mutation with no effect:2469-2469,2545-2545	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P41240	uniprotkb:Q7VLE8	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003.9|ensembl:ENSP00000414764.2|ensembl:ENSP00000454906.1	intact:EBI-26445163	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	"psi-mi:""MI:0096""(pull down)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445249|imex:IM-28484-9	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653.17(gene)|ensembl:ENST00000220003.14(transcript)|ensembl:ENST00000439220.6(transcript)|ensembl:ENST00000567571.5(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010989""(negative regulation of low-density lipoprotein particle clearance)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0042997""(negative regulation of Golgi to plasma membrane protein transport)|go:""GO:0045779""(negative regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369|panther:PTHR24418(orthology-group)|refseq:NP_001120662.1|refseq:NP_004374.1"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	-	-	-	figure legend:fig. 3 e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/10/30	2024/11/14	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	intact-crc:A44C2B5B67EE8867|rigid:85sxEUympoaby8ljyKHdd5PiS4Q	false	flag tag:?-?|binding-associated region:82..82-171..171	strep tag:?-?|binding-associated region:2469-2545|mutation decreasing interaction:2469-2469,2545-2545	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P06493	uniprotkb:Q7VLE8	intact:EBI-444308|ensembl:ENSP00000378699.3|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4	intact:EBI-26445163	psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym)	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	"psi-mi:""MI:0424""(protein kinase assay)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	"psi-mi:""MI:0217""(phosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445287|imex:IM-28484-10	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0840""(stimulator)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000170312.17(gene)|ensembl:ENST00000395284.8(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000307""(cyclin-dependent protein kinase holoenzyme complex)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003682""(chromatin binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004693""(cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005876""(spindle microtubule)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0007077""(mitotic nuclear membrane disassembly)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007344""(pronuclear fusion)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010971""(positive regulation of G2/M transition of mitotic cell cycle)|go:""GO:0014038""(regulation of Schwann cell differentiation)|go:""GO:0014075""(response to amine)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0016477""(cell migration)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0030261""(chromosome condensation)|go:""GO:0030332""(cyclin binding)|go:""GO:0030496""(midbody)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0034501""(protein localization to kinetochore)|go:""GO:0035173""(histone kinase activity)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045471""(response to ethanol)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046686""(response to cadmium ion)|go:""GO:0046688""(response to copper ion)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048511""(rhythmic process)|go:""GO:0048678""(response to axon injury)|go:""GO:0051301""(cell division)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0062033""(positive regulation of mitotic sister chromatid segregation)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090166""(Golgi disassembly)|go:""GO:0097121""(cyclin A1-CDK1 complex)|go:""GO:0097122""(cyclin A2-CDK1 complex)|go:""GO:0097125""(cyclin B1-CDK1 complex)|go:""GO:0097472""(cyclin-dependent protein kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140833""(RNA polymerase II CTD heptapeptide repeat Y1 kinase activity)|go:""GO:0140834""(RNA polymerase II CTD heptapeptide repeat S2 kinase activity)|go:""GO:0140835""(RNA polymerase II CTD heptapeptide repeat T4 kinase activity)|go:""GO:0140836""(RNA polymerase II CTD heptapeptide repeat S5 kinase activity)|go:""GO:0140837""(RNA polymerase II CTD heptapeptide repeat S7 kinase activity)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902423""(regulation of attachment of mitotic spindle microtubules to kinetochore)|go:""GO:1902850""(microtubule cytoskeleton organization involved in mitosis)|go:""GO:1905448""(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050108|mint:P06493|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|rcsb pdb:6GU7|rcsb pdb:6TWN|rcsb pdb:7NJ0|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|reactome:R-HSA-9833482|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N|panther:PTHR24056(orthology-group)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	-	-	-	"figure legend:fig. 5a|comment:""\""To investigate whether YL2 could directly activate Csk, a  tyrosine kinase assay that measures phosphorylation of a poly  (Glu-Tyr) peptide was performed with recombinant Csk and recombinant YL2, YL2-DM, or L1. Increasing concentrations of  YL2 increased Csk activity in a dose-dependent manner (Fig. 5).  When 65 nM Csk and 50 nM YL2 were incubated together, therewas a 10-fold increase in Csk activity (Fig. 5A). YL2 itself had no  kinase activity, and YL2-DM did not stimulate Csk activity\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/30	2025/02/27	rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	intact-crc:ACA409107D2CE80A|rigid:KFFIGURjrjMFlw6OK/X4OkcgYRw	false	binding-associated region:6-20	binding-associated region:2349-2643|mutation disrupting interaction:2469-2469,2545-2545	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:P41240	uniprotkb:Q7VLE8	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003.9|ensembl:ENSP00000414764.2|ensembl:ENSP00000454906.1	intact:EBI-26445163	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	psi-mi:q7vle8_haedu(display_long)|uniprotkb:lspA1(gene name)|psi-mi:lspA1(display_short)|uniprotkb:HD_1505(locus name)	"psi-mi:""MI:0424""(protein kinase assay)"	Dodd et al. (2014)	pubmed:24902122|imex:IM-28484	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:233412(haedu)|taxid:233412(""Haemophilus ducreyi (strain 35000HP / ATCC 700724)"")"	"psi-mi:""MI:0217""(phosphorylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26445300|imex:IM-28484-12	intact-miscore:0.59	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653.17(gene)|ensembl:ENST00000220003.14(transcript)|ensembl:ENST00000439220.6(transcript)|ensembl:ENST00000567571.5(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010989""(negative regulation of low-density lipoprotein particle clearance)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0042997""(negative regulation of Golgi to plasma membrane protein transport)|go:""GO:0045779""(negative regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369|panther:PTHR24418(orthology-group)|refseq:NP_001120662.1|refseq:NP_004374.1"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|mint:Q7VLE8|refseq:WP_010945345.1|interpro:IPR024973|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR025157|interpro:IPR038765|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR006473(Peptidase C58, yopT)"	-	-	-	"figure legend:fig. 5b|comment:""\""To investigate whether YL2 could directly activate Csk, a  tyrosine kinase assay that measures phosphorylation of a poly  (Glu-Tyr) peptide was performed with recombinant Csk and recombinant YL2, YL2-DM, or L1. Increasing concentrations of  YL2 increased Csk activity in a dose-dependent manner (Fig. 5).  When 65 nM Csk and 50 nM YL2 were incubated together, therewas a 10-fold increase in Csk activity (Fig. 5A). YL2 itself had no  kinase activity, and YL2-DM did not stimulate Csk activity\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/30	2024/11/14	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	rogid:u12Gr1AcrUX1rcp3WgGDhgzgpfo233412	intact-crc:1A0224CF69911C5C|rigid:85sxEUympoaby8ljyKHdd5PiS4Q	false	-	binding-associated region:2349-2643	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q04884	uniprotkb:P13688	intact:EBI-26495102	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	psi-mi:opah_neigo(display_long)|uniprotkb:opaH(gene name)|psi-mi:opaH(display_short)	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Martin et al. (2016)	pubmed:27442026|imex:IM-28538	taxid:485(neigo)|taxid:485(Neisseria gonorrhoeae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26495100|imex:IM-28538-1	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR003394(Porin, opacity type)|mint:Q04884|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|rcsb pdb:2MAF|rcsb pdb:2MLH|rcsb pdb:8QWQ|reactome:R-HSA-202733"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)"	-	-	-	"figure legend:fig. 3a|comment:""\""To determine if Opa proteins retain their ability to interact with receptors in vitro, pull-down assays were performed with Opa proteins reconstituted into small unilamellar liposomes (less than 100 nm).\""""|comment:Opa60 and OpaD proteoliposome pellets contained both NCCM1 and 3, indicating that these Opa proteins retain their ability to interact with both NCCM1 and 3 when recombinantly expressed and reconstituted into liposomes. For NCCM1, weaker bands are observed for Opa50 and OpaTrp compared to Opa60 and OpaD, indicating that there is some non-specific interaction of NCCM1 with the liposomes. For NCCM3, a band is also observed in the pellet with both OpaTrp and Opa50, indicating non-specific interactions are occurring.|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/13	2024/11/14	rogid:VAY4+NXS07xZEkQP+AjL1/i2YpQ485	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	intact-crc:ACBE5562B1EAE429|rigid:DcmqN2qrHPEMmas2NDa9GWlHWek	false	-	binding-associated region:35-141|glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q04883	uniprotkb:P13688	intact:EBI-26495131	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	psi-mi:opad_neigo(display_long)|uniprotkb:opaD(gene name)|psi-mi:opaD(display_short)	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Martin et al. (2016)	pubmed:27442026|imex:IM-28538	taxid:485(neigo)|taxid:485(Neisseria gonorrhoeae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26495142|imex:IM-28538-3	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR003394(Porin, opacity type)|mint:Q04883|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|reactome:R-HSA-202733"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)"	-	-	-	"figure legend:fig. 3a|comment:""\""To determine if Opa proteins retain their ability to interact with receptors in vitro, pull-down assays were performed with Opa proteins reconstituted into small unilamellar liposomes (less than 100 nm).\""""|comment:Opa60 and OpaD proteoliposome pellets contained both NCCM1 and 3, indicating that these Opa proteins retain their ability to interact with both NCCM1 and 3 when recombinantly expressed and reconstituted into liposomes. For NCCM1, weaker bands are observed for Opa50 and OpaTrp compared to Opa60 and OpaD, indicating that there is some non-specific interaction of NCCM1 with the liposomes. For NCCM3, a band is also observed in the pellet with both OpaTrp and Opa50, indicating non-specific interactions are occurring.|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/13	2024/11/14	rogid:RAidSbUALYol48WGeHFv2SRePU4485	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	intact-crc:74F5D40E83CC0232|rigid:E0hdJHoOOEHYhIaVd6tgiY/gW+s	false	-	binding-associated region:35-141|glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q04884	uniprotkb:P40198	intact:EBI-26495102	intact:EBI-12851752|uniprotkb:G5E978|uniprotkb:Q3KPH9|ensembl:ENSP00000349971.3	psi-mi:opah_neigo(display_long)|uniprotkb:opaH(gene name)|psi-mi:opaH(display_short)	psi-mi:ceam3_human(display_long)|uniprotkb:CEACAM3(gene name)|psi-mi:CEACAM3(display_short)|uniprotkb:CD66D(gene name synonym)|uniprotkb:CGM1(gene name synonym)|uniprotkb:Carcinoembryonic antigen CGM1(gene name synonym)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Martin et al. (2016)	pubmed:27442026|imex:IM-28538	taxid:485(neigo)|taxid:485(Neisseria gonorrhoeae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26495152|imex:IM-28538-5	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR003394(Porin, opacity type)|mint:Q04884|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|rcsb pdb:2MAF|rcsb pdb:2MLH|rcsb pdb:8QWQ|reactome:R-HSA-202733"	"efo:""Orphanet:586""|panther:PTHR44427(orthology-group)|ensembl:ENSG00000170956.17(gene)|ensembl:ENST00000357396.8(transcript)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0009986""(cell surface)|go:""GO:0035579""(specific granule membrane)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P40198|rcsb pdb:6AVZ|rcsb pdb:6AW0|rcsb pdb:6AW1|rcsb pdb:6AW3|reactome:R-HSA-202733|reactome:R-HSA-6798695|refseq:NP_001264092.1|refseq:NP_001806.2"	-	-	-	"figure legend:fig. 3b|comment:""\""To determine if Opa proteins retain their ability to interact with receptors in vitro, pull-down assays were performed with Opa proteins reconstituted into small unilamellar liposomes (less than 100 nm).\""""|comment:Opa60 and OpaD proteoliposome pellets contained both NCCM1 and 3, indicating that these Opa proteins retain their ability to interact with both NCCM1 and 3 when recombinantly expressed and reconstituted into liposomes. For NCCM1, weaker bands are observed for Opa50 and OpaTrp compared to Opa60 and OpaD, indicating that there is some non-specific interaction of NCCM1 with the liposomes. For NCCM3, a band is also observed in the pellet with both OpaTrp and Opa50, indicating non-specific interactions are occurring.|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/13	2024/11/14	rogid:VAY4+NXS07xZEkQP+AjL1/i2YpQ485	rogid:Ziog7tYFiTOSwfKXaS9o3u/kirg9606	intact-crc:F339B9D8CFF7794F|rigid:+MDx8uR1Cl8f6KwMuUCTtyAWXXY	false	-	binding-associated region:35-142|glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q04883	uniprotkb:P40198	intact:EBI-26495131	intact:EBI-12851752|uniprotkb:G5E978|uniprotkb:Q3KPH9|ensembl:ENSP00000349971.3	psi-mi:opad_neigo(display_long)|uniprotkb:opaD(gene name)|psi-mi:opaD(display_short)	psi-mi:ceam3_human(display_long)|uniprotkb:CEACAM3(gene name)|psi-mi:CEACAM3(display_short)|uniprotkb:CD66D(gene name synonym)|uniprotkb:CGM1(gene name synonym)|uniprotkb:Carcinoembryonic antigen CGM1(gene name synonym)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Martin et al. (2016)	pubmed:27442026|imex:IM-28538	taxid:485(neigo)|taxid:485(Neisseria gonorrhoeae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26495163|imex:IM-28538-7	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR003394(Porin, opacity type)|mint:Q04883|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|reactome:R-HSA-202733"	"efo:""Orphanet:586""|panther:PTHR44427(orthology-group)|ensembl:ENSG00000170956.17(gene)|ensembl:ENST00000357396.8(transcript)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0009986""(cell surface)|go:""GO:0035579""(specific granule membrane)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P40198|rcsb pdb:6AVZ|rcsb pdb:6AW0|rcsb pdb:6AW1|rcsb pdb:6AW3|reactome:R-HSA-202733|reactome:R-HSA-6798695|refseq:NP_001264092.1|refseq:NP_001806.2"	-	-	-	"figure legend:fig. 3b|comment:""\""To determine if Opa proteins retain their ability to interact with receptors in vitro, pull-down assays were performed with Opa proteins reconstituted into small unilamellar liposomes (less than 100 nm).\""""|comment:Opa60 and OpaD proteoliposome pellets contained both NCCM1 and 3, indicating that these Opa proteins retain their ability to interact with both NCCM1 and 3 when recombinantly expressed and reconstituted into liposomes. For NCCM1, weaker bands are observed for Opa50 and OpaTrp compared to Opa60 and OpaD, indicating that there is some non-specific interaction of NCCM1 with the liposomes. For NCCM3, a band is also observed in the pellet with both OpaTrp and Opa50, indicating non-specific interactions are occurring.|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/13	2024/11/14	rogid:RAidSbUALYol48WGeHFv2SRePU4485	rogid:Ziog7tYFiTOSwfKXaS9o3u/kirg9606	intact-crc:2B7238B4FDD19F54|rigid:+1JSnIgHja6UngC/RwW/M0zdlaU	false	-	binding-associated region:35-142|glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P13688	uniprotkb:Q04884	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-26495102	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:opah_neigo(display_long)|uniprotkb:opaH(gene name)|psi-mi:opaH(display_short)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Martin et al. (2016)	pubmed:27442026|imex:IM-28538	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:485(neigo)|taxid:485(Neisseria gonorrhoeae)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26495198|imex:IM-28538-8	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)"	"interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR003394(Porin, opacity type)|mint:Q04884|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|rcsb pdb:2MAF|rcsb pdb:2MLH|rcsb pdb:8QWQ|reactome:R-HSA-202733"	-	-	-	figure legend:fig 4a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.6x10^-9 ~0.6(molar)	2020/11/13	2024/11/14	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:VAY4+NXS07xZEkQP+AjL1/i2YpQ485	intact-crc:096ADF74CF39CD79|rigid:DcmqN2qrHPEMmas2NDa9GWlHWek	false	mutation:139-139|binding-associated region:35-141|fluorescent dye label:139-139	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P13688	uniprotkb:Q04883	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-26495131	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:opad_neigo(display_long)|uniprotkb:opaD(gene name)|psi-mi:opaD(display_short)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Martin et al. (2016)	pubmed:27442026|imex:IM-28538	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:485(neigo)|taxid:485(Neisseria gonorrhoeae)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26495210|imex:IM-28538-10	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)"	"interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR003394(Porin, opacity type)|mint:Q04883|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|reactome:R-HSA-202733"	-	-	-	figure legend:fig 4b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.6x10^-9 ~1.3(molar)	2020/11/13	2024/11/14	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:RAidSbUALYol48WGeHFv2SRePU4485	intact-crc:C7647976994FFF8B|rigid:E0hdJHoOOEHYhIaVd6tgiY/gW+s	false	mutation:139-139|binding-associated region:35-141|fluorescent dye label:139-139	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P40198	uniprotkb:Q04884	intact:EBI-12851752|uniprotkb:G5E978|uniprotkb:Q3KPH9|ensembl:ENSP00000349971.3	intact:EBI-26495102	psi-mi:ceam3_human(display_long)|uniprotkb:CEACAM3(gene name)|psi-mi:CEACAM3(display_short)|uniprotkb:CD66D(gene name synonym)|uniprotkb:CGM1(gene name synonym)|uniprotkb:Carcinoembryonic antigen CGM1(gene name synonym)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 3(gene name synonym)	psi-mi:opah_neigo(display_long)|uniprotkb:opaH(gene name)|psi-mi:opaH(display_short)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Martin et al. (2016)	pubmed:27442026|imex:IM-28538	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:485(neigo)|taxid:485(Neisseria gonorrhoeae)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26495221|imex:IM-28538-12	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:586""|panther:PTHR44427(orthology-group)|ensembl:ENSG00000170956.17(gene)|ensembl:ENST00000357396.8(transcript)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0009986""(cell surface)|go:""GO:0035579""(specific granule membrane)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P40198|rcsb pdb:6AVZ|rcsb pdb:6AW0|rcsb pdb:6AW1|rcsb pdb:6AW3|reactome:R-HSA-202733|reactome:R-HSA-6798695|refseq:NP_001264092.1|refseq:NP_001806.2"	"interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR003394(Porin, opacity type)|mint:Q04884|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|rcsb pdb:2MAF|rcsb pdb:2MLH|rcsb pdb:8QWQ|reactome:R-HSA-202733"	-	-	-	figure legend:fig 4c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.3x10^-9 ~2.8(molar)	2020/11/13	2024/11/14	rogid:Ziog7tYFiTOSwfKXaS9o3u/kirg9606	rogid:VAY4+NXS07xZEkQP+AjL1/i2YpQ485	intact-crc:BF5F00CD511B5458|rigid:+MDx8uR1Cl8f6KwMuUCTtyAWXXY	false	mutation:139-139|binding-associated region:35-142|fluorescent dye label:139-139	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P40198	uniprotkb:Q04883	intact:EBI-12851752|uniprotkb:G5E978|uniprotkb:Q3KPH9|ensembl:ENSP00000349971.3	intact:EBI-26495131	psi-mi:ceam3_human(display_long)|uniprotkb:CEACAM3(gene name)|psi-mi:CEACAM3(display_short)|uniprotkb:CD66D(gene name synonym)|uniprotkb:CGM1(gene name synonym)|uniprotkb:Carcinoembryonic antigen CGM1(gene name synonym)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 3(gene name synonym)	psi-mi:opad_neigo(display_long)|uniprotkb:opaD(gene name)|psi-mi:opaD(display_short)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Martin et al. (2016)	pubmed:27442026|imex:IM-28538	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:485(neigo)|taxid:485(Neisseria gonorrhoeae)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26495232|imex:IM-28538-14	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:586""|panther:PTHR44427(orthology-group)|ensembl:ENSG00000170956.17(gene)|ensembl:ENST00000357396.8(transcript)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0009986""(cell surface)|go:""GO:0035579""(specific granule membrane)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P40198|rcsb pdb:6AVZ|rcsb pdb:6AW0|rcsb pdb:6AW1|rcsb pdb:6AW3|reactome:R-HSA-202733|reactome:R-HSA-6798695|refseq:NP_001264092.1|refseq:NP_001806.2"	"interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR003394(Porin, opacity type)|mint:Q04883|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|reactome:R-HSA-202733"	-	-	-	figure legend:fig 4d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.8x10^-9 ~2.2(molar)	2020/11/13	2024/11/14	rogid:Ziog7tYFiTOSwfKXaS9o3u/kirg9606	rogid:RAidSbUALYol48WGeHFv2SRePU4485	intact-crc:715766CF076D66AA|rigid:+1JSnIgHja6UngC/RwW/M0zdlaU	false	mutation:139-139|binding-associated region:35-142|fluorescent dye label:139-139	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P13688	uniprotkb:Q04884	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-26495102	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:opah_neigo(display_long)|uniprotkb:opaH(gene name)|psi-mi:opaH(display_short)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Martin et al. (2016)	pubmed:27442026|imex:IM-28538	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:485(neigo)|taxid:485(Neisseria gonorrhoeae)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26495264|imex:IM-28538-16	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)"	"interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR003394(Porin, opacity type)|mint:Q04884|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|rcsb pdb:2MAF|rcsb pdb:2MLH|rcsb pdb:8QWQ|reactome:R-HSA-202733"	-	-	-	figure legend:suppl fig 9a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.0x10^-9 ~2.1(molar)	2020/11/13	2024/11/14	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:VAY4+NXS07xZEkQP+AjL1/i2YpQ485	intact-crc:C2BCC3FACDC162FC|rigid:DcmqN2qrHPEMmas2NDa9GWlHWek	false	mutation:139-139|binding-associated region:35-141|fluorescent dye label:139-139	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P40198	uniprotkb:Q04884	intact:EBI-12851752|uniprotkb:G5E978|uniprotkb:Q3KPH9|ensembl:ENSP00000349971.3	intact:EBI-26495102	psi-mi:ceam3_human(display_long)|uniprotkb:CEACAM3(gene name)|psi-mi:CEACAM3(display_short)|uniprotkb:CD66D(gene name synonym)|uniprotkb:CGM1(gene name synonym)|uniprotkb:Carcinoembryonic antigen CGM1(gene name synonym)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 3(gene name synonym)	psi-mi:opah_neigo(display_long)|uniprotkb:opaH(gene name)|psi-mi:opaH(display_short)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Martin et al. (2016)	pubmed:27442026|imex:IM-28538	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:485(neigo)|taxid:485(Neisseria gonorrhoeae)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26495465|imex:IM-28538-18	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:586""|panther:PTHR44427(orthology-group)|ensembl:ENSG00000170956.17(gene)|ensembl:ENST00000357396.8(transcript)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0009986""(cell surface)|go:""GO:0035579""(specific granule membrane)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P40198|rcsb pdb:6AVZ|rcsb pdb:6AW0|rcsb pdb:6AW1|rcsb pdb:6AW3|reactome:R-HSA-202733|reactome:R-HSA-6798695|refseq:NP_001264092.1|refseq:NP_001806.2"	"interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR003394(Porin, opacity type)|mint:Q04884|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|rcsb pdb:2MAF|rcsb pdb:2MLH|rcsb pdb:8QWQ|reactome:R-HSA-202733"	-	-	-	figure legend:suppl fig 9b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:20.0x10^-9 ~6.5(molar)	2020/11/13	2024/11/14	rogid:Ziog7tYFiTOSwfKXaS9o3u/kirg9606	rogid:VAY4+NXS07xZEkQP+AjL1/i2YpQ485	intact-crc:DD8ED5FBB0206FFE|rigid:+MDx8uR1Cl8f6KwMuUCTtyAWXXY	false	mutation:139-139|binding-associated region:35-142|fluorescent dye label:139-139	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P18206	uniprotkb:P18010	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	intact:EBI-7640410|intact:MINT-6174234|uniprotkb:Q8VSH8	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	psi-mi:ipaa_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)|uniprotkb:CP0125(locus name)|uniprotkb:70 kDa antigen(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Park et al. (2011)	pubmed:21525010|imex:IM-28531	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26494529|imex:IM-28531-1	intact-miscore:0.76	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	"refseq:NP_085287.1|interpro:IPR015138(Salmonella invasion protein A)|refseq:NP_858258.1|interpro:IPR023225|refseq:YP_009062482.1|refseq:WP_005063225.1|mint:P18010|interpro:IPR040658|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0017166""(vinculin binding)|go:""GO:0030836""(positive regulation of actin filament depolymerization)|rcsb pdb:2GDC|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3RF3|rcsb pdb:5NL1"	pdbe:3RF3	-	function:Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex ipaA-vinculin induces F-actin depolymerization along with the occasional formation of actin filament bundles|comment:mint	figure legend:table 1-2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/18	2025/02/28	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	rogid:4+8tCJOGJJMiLIFxkqnnF4Jr6w0623	intact-crc:0FCFB2FAFEAF8D25|rigid:CnsVdxtkVYkDpUWGQttk1Ddtuok	false	binding-associated region:1-258	binding-associated region:488-512	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P18206	uniprotkb:P18010	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	intact:EBI-7640410|intact:MINT-6174234|uniprotkb:Q8VSH8	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	psi-mi:ipaa_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)|uniprotkb:CP0125(locus name)|uniprotkb:70 kDa antigen(gene name synonym)	"psi-mi:""MI:0276""(blue native page)"	Park et al. (2011)	pubmed:21525010|imex:IM-28531	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26494594|imex:IM-28531-3	intact-miscore:0.76	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	"refseq:NP_085287.1|interpro:IPR015138(Salmonella invasion protein A)|refseq:NP_858258.1|interpro:IPR023225|refseq:YP_009062482.1|refseq:WP_005063225.1|mint:P18010|interpro:IPR040658|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0017166""(vinculin binding)|go:""GO:0030836""(positive regulation of actin filament depolymerization)|rcsb pdb:2GDC|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3RF3|rcsb pdb:5NL1"	-	-	function:Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex ipaA-vinculin induces F-actin depolymerization along with the occasional formation of actin filament bundles|comment:mint	figure legend:fig. 2a - 2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/18	2025/02/28	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	rogid:4+8tCJOGJJMiLIFxkqnnF4Jr6w0623	intact-crc:02FA4A846C88A282|rigid:CnsVdxtkVYkDpUWGQttk1Ddtuok	false	binding-associated region:1-258	binding-associated region:488-512|mutation disrupting interaction:499-499,503-503|maltose binding protein tag:n-n	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:P18010	uniprotkb:P18206	intact:EBI-7640410|intact:MINT-6174234|uniprotkb:Q8VSH8	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:ipaa_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)|uniprotkb:CP0125(locus name)|uniprotkb:70 kDa antigen(gene name synonym)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0276""(blue native page)"	Park et al. (2011)	pubmed:21525010|imex:IM-28531	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26494647|imex:IM-28531-7	intact-miscore:0.76	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_085287.1|interpro:IPR015138(Salmonella invasion protein A)|refseq:NP_858258.1|interpro:IPR023225|refseq:YP_009062482.1|refseq:WP_005063225.1|mint:P18010|interpro:IPR040658|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0017166""(vinculin binding)|go:""GO:0030836""(positive regulation of actin filament depolymerization)|rcsb pdb:2GDC|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3RF3|rcsb pdb:5NL1"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	-	function:Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex ipaA-vinculin induces F-actin depolymerization along with the occasional formation of actin filament bundles|comment:mint	-	figure legend:fig.4a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/18	2025/02/28	rogid:4+8tCJOGJJMiLIFxkqnnF4Jr6w0623	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:59DA97CDE055E399|rigid:CnsVdxtkVYkDpUWGQttk1Ddtuok	false	binding-associated region:488-512	binding-associated region:1-258	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:P18010	uniprotkb:P18206	intact:EBI-7640410|intact:MINT-6174234|uniprotkb:Q8VSH8	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:ipaa_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)|uniprotkb:CP0125(locus name)|uniprotkb:70 kDa antigen(gene name synonym)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0276""(blue native page)"	Park et al. (2011)	pubmed:21525010|imex:IM-28531	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26494647|imex:IM-28531-7	intact-miscore:0.76	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_085287.1|interpro:IPR015138(Salmonella invasion protein A)|refseq:NP_858258.1|interpro:IPR023225|refseq:YP_009062482.1|refseq:WP_005063225.1|mint:P18010|interpro:IPR040658|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0017166""(vinculin binding)|go:""GO:0030836""(positive regulation of actin filament depolymerization)|rcsb pdb:2GDC|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3RF3|rcsb pdb:5NL1"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	-	function:Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex ipaA-vinculin induces F-actin depolymerization along with the occasional formation of actin filament bundles|comment:mint	-	figure legend:fig.4a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/18	2025/02/28	rogid:4+8tCJOGJJMiLIFxkqnnF4Jr6w0623	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:59DA97CDE055E399|rigid:CnsVdxtkVYkDpUWGQttk1Ddtuok	false	binding-associated region:488-512	binding-associated region:879-1066	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:P18010	uniprotkb:P18206	intact:EBI-7640410|intact:MINT-6174234|uniprotkb:Q8VSH8	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:ipaa_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)|uniprotkb:CP0125(locus name)|uniprotkb:70 kDa antigen(gene name synonym)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Park et al. (2011)	pubmed:21525010|imex:IM-28531	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26494637|imex:IM-28531-5	intact-miscore:0.76	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_085287.1|interpro:IPR015138(Salmonella invasion protein A)|refseq:NP_858258.1|interpro:IPR023225|refseq:YP_009062482.1|refseq:WP_005063225.1|mint:P18010|interpro:IPR040658|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0017166""(vinculin binding)|go:""GO:0030836""(positive regulation of actin filament depolymerization)|rcsb pdb:2GDC|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3RF3|rcsb pdb:5NL1"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	-	function:Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex ipaA-vinculin induces F-actin depolymerization along with the occasional formation of actin filament bundles|comment:mint	-	figure legend:fig. 2c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.054x10^-9(molar)	2020/11/18	2025/02/28	rogid:4+8tCJOGJJMiLIFxkqnnF4Jr6w0623	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:CA0E045482F8C1FA|rigid:CnsVdxtkVYkDpUWGQttk1Ddtuok	false	binding-associated region:488-512|mutation decreasing interaction:495-495	binding-associated region:1-258	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q04206	uniprotkb:B3CTB0	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	intact:EBI-26357538	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:b3ctb0_oriti(display_long)|uniprotkb:OTT_1149(locus name)|uniprotkb:OTT_1496(locus name)|uniprotkb:OTT_1912(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357549|imex:IM-28371-1	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	mint:B3CTB0|refseq:WP_012461684.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	-	-	-	figure legend:F8|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2025/03/26	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rogid:FwuChLb9svxQPVSXV64trbMs7/c334380	intact-crc:16A7BC67251A0569|rigid:PmBkEwnr1Y/vlcwzy9FCCBRpo64	false	-	flag tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q04206	uniprotkb:B3CRR2	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	intact:EBI-26357571	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:b3crr2_oriti(display_long)|uniprotkb:OTT_0753(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357580|imex:IM-28371-3	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	mint:B3CRR2|refseq:WP_012461365.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	-	-	-	figure legend:F8|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2025/03/26	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rogid:/+kMBD+4JlGdPh2Mxthf507gJIE334380	intact-crc:7C5FFB13685ED124|rigid:hWydt1DlXDiJwe4WJxXHiAGpsLs	false	-	flag tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B3CRR2	uniprotkb:Q04206	intact:EBI-26357571	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	psi-mi:b3crr2_oriti(display_long)|uniprotkb:OTT_0753(locus name)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357604|imex:IM-28371-7	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B3CRR2|refseq:WP_012461365.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	-	-	-	figure legend:F9 F15|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2025/03/26	rogid:/+kMBD+4JlGdPh2Mxthf507gJIE334380	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:6CB1FF65B073D33D|rigid:uiTSJAGaELLa5aiO6sPKaFKHNRc	false	flag tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B3CRR2	uniprotkb:Q14974	intact:EBI-26357571	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|ensembl:ENSP00000290158.3|ensembl:ENSP00000464042.2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864	psi-mi:b3crr2_oriti(display_long)|uniprotkb:OTT_0753(locus name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357604|imex:IM-28371-7	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B3CRR2|refseq:WP_012461365.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	"ensembl:ENSG00000108424.11(gene)|ensembl:ENST00000290158.9(transcript)|ensembl:ENST00000583648.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006404""(RNA import into nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0006610""(ribosomal protein import into nucleus)|go:""GO:0007079""(mitotic chromosome movement towards spindle pole)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035580""(specific granule lumen)|go:""GO:0040001""(establishment of mitotic spindle localization)|go:""GO:0042564""(NLS-dependent protein nuclear import complex)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:8GCN|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-68616|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249|reactome:R-HSA-9692916|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|panther:PTHR10527(orthology-group)"	-	-	-	figure legend:F9 F15|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2025/03/26	rogid:/+kMBD+4JlGdPh2Mxthf507gJIE334380	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	intact-crc:6CB1FF65B073D33D|rigid:uiTSJAGaELLa5aiO6sPKaFKHNRc	false	flag tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B3CRR2	uniprotkb:O14980	intact:EBI-26357571	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863.2|ensembl:ENSP00000385559.1|ensembl:ENSP00000385942.2|ensembl:ENSP00000503167.1|ensembl:ENSP00000503419.1|ensembl:ENSP00000503482.1|ensembl:ENSP00000503572.1|ensembl:ENSP00000503809.1|ensembl:ENSP00000504087.1|ensembl:ENSP00000504198.1|ensembl:ENSP00000504247.1|ensembl:ENSP00000504543.1|ensembl:ENSP00000504594.1|ensembl:ENSP00000504848.1	psi-mi:b3crr2_oriti(display_long)|uniprotkb:OTT_0753(locus name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357604|imex:IM-28371-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B3CRR2|refseq:WP_012461365.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	"efo:""Orphanet:98838""|ensembl:ENSG00000082898.19(gene)|ensembl:ENST00000401558.7(transcript)|ensembl:ENST00000404992.6(transcript)|ensembl:ENST00000406957.5(transcript)|ensembl:ENST00000676553.1(transcript)|ensembl:ENST00000676667.1(transcript)|ensembl:ENST00000677150.1(transcript)|ensembl:ENST00000677239.1(transcript)|ensembl:ENST00000677417.1(transcript)|ensembl:ENST00000677813.1(transcript)|ensembl:ENST00000677814.1(transcript)|ensembl:ENST00000677928.1(transcript)|ensembl:ENST00000677933.1(transcript)|ensembl:ENST00000678182.1(transcript)|ensembl:ENST00000678790.1(transcript)|go:""GO:0000054""(ribosomal subunit export from nucleus)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0000776""(kinetochore)|go:""GO:0003723""(RNA binding)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005642""(annulate lamellae)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015030""(Cajal body)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032434""(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|interpro:IPR045065|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|rcsb pdb:7B51|rcsb pdb:9B62|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|reactome:R-HSA-9768919|reactome:R-HSA-9828806|reactome:R-HSA-9856649|refseq:NP_003391.1|refseq:XP_006712157.1|refseq:XP_011531399.1|dip:DIP-33678N|panther:PTHR11223(orthology-group)|ensembl:ENSP00000384863.2|ensembl:ENSP00000385942.2|ensembl:ENSP00000385559.1|ensembl:ENSP00000504247.1|ensembl:ENSP00000503809.1|ensembl:ENSP00000503167.1|ensembl:ENSP00000504087.1|ensembl:ENSP00000503572.1|ensembl:ENSP00000504543.1|ensembl:ENSP00000504848.1|ensembl:ENSP00000504198.1|ensembl:ENSP00000503482.1|ensembl:ENSP00000504594.1|ensembl:ENSP00000503419.1"	-	-	-	figure legend:F9 F15|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2025/03/26	rogid:/+kMBD+4JlGdPh2Mxthf507gJIE334380	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	intact-crc:6CB1FF65B073D33D|rigid:uiTSJAGaELLa5aiO6sPKaFKHNRc	false	flag tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B3CTB0	uniprotkb:Q04206	intact:EBI-26357538	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	psi-mi:b3ctb0_oriti(display_long)|uniprotkb:OTT_1149(locus name)|uniprotkb:OTT_1496(locus name)|uniprotkb:OTT_1912(locus name)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357616|imex:IM-28371-9	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B3CTB0|refseq:WP_012461684.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	-	-	-	figure legend:F9 F15|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2025/03/26	rogid:FwuChLb9svxQPVSXV64trbMs7/c334380	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:F5E4E23436719594|rigid:8HbS7BTYC1ZVODgFVgkQDDWaFas	false	necessary binding region:22-121,168-202|flag tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B3CTB0	uniprotkb:Q14974	intact:EBI-26357538	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|ensembl:ENSP00000290158.3|ensembl:ENSP00000464042.2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864	psi-mi:b3ctb0_oriti(display_long)|uniprotkb:OTT_1149(locus name)|uniprotkb:OTT_1496(locus name)|uniprotkb:OTT_1912(locus name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357616|imex:IM-28371-9	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B3CTB0|refseq:WP_012461684.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	"ensembl:ENSG00000108424.11(gene)|ensembl:ENST00000290158.9(transcript)|ensembl:ENST00000583648.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006404""(RNA import into nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0006610""(ribosomal protein import into nucleus)|go:""GO:0007079""(mitotic chromosome movement towards spindle pole)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035580""(specific granule lumen)|go:""GO:0040001""(establishment of mitotic spindle localization)|go:""GO:0042564""(NLS-dependent protein nuclear import complex)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:8GCN|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-68616|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249|reactome:R-HSA-9692916|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|panther:PTHR10527(orthology-group)"	-	-	-	figure legend:F9 F15|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2025/03/26	rogid:FwuChLb9svxQPVSXV64trbMs7/c334380	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	intact-crc:F5E4E23436719594|rigid:8HbS7BTYC1ZVODgFVgkQDDWaFas	false	necessary binding region:22-121,168-202|flag tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B3CTB0	uniprotkb:O14980	intact:EBI-26357538	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863.2|ensembl:ENSP00000385559.1|ensembl:ENSP00000385942.2|ensembl:ENSP00000503167.1|ensembl:ENSP00000503419.1|ensembl:ENSP00000503482.1|ensembl:ENSP00000503572.1|ensembl:ENSP00000503809.1|ensembl:ENSP00000504087.1|ensembl:ENSP00000504198.1|ensembl:ENSP00000504247.1|ensembl:ENSP00000504543.1|ensembl:ENSP00000504594.1|ensembl:ENSP00000504848.1	psi-mi:b3ctb0_oriti(display_long)|uniprotkb:OTT_1149(locus name)|uniprotkb:OTT_1496(locus name)|uniprotkb:OTT_1912(locus name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357616|imex:IM-28371-9	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B3CTB0|refseq:WP_012461684.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	"efo:""Orphanet:98838""|ensembl:ENSG00000082898.19(gene)|ensembl:ENST00000401558.7(transcript)|ensembl:ENST00000404992.6(transcript)|ensembl:ENST00000406957.5(transcript)|ensembl:ENST00000676553.1(transcript)|ensembl:ENST00000676667.1(transcript)|ensembl:ENST00000677150.1(transcript)|ensembl:ENST00000677239.1(transcript)|ensembl:ENST00000677417.1(transcript)|ensembl:ENST00000677813.1(transcript)|ensembl:ENST00000677814.1(transcript)|ensembl:ENST00000677928.1(transcript)|ensembl:ENST00000677933.1(transcript)|ensembl:ENST00000678182.1(transcript)|ensembl:ENST00000678790.1(transcript)|go:""GO:0000054""(ribosomal subunit export from nucleus)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0000776""(kinetochore)|go:""GO:0003723""(RNA binding)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005642""(annulate lamellae)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015030""(Cajal body)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032434""(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|interpro:IPR045065|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|rcsb pdb:7B51|rcsb pdb:9B62|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|reactome:R-HSA-9768919|reactome:R-HSA-9828806|reactome:R-HSA-9856649|refseq:NP_003391.1|refseq:XP_006712157.1|refseq:XP_011531399.1|dip:DIP-33678N|panther:PTHR11223(orthology-group)|ensembl:ENSP00000384863.2|ensembl:ENSP00000385942.2|ensembl:ENSP00000385559.1|ensembl:ENSP00000504247.1|ensembl:ENSP00000503809.1|ensembl:ENSP00000503167.1|ensembl:ENSP00000504087.1|ensembl:ENSP00000503572.1|ensembl:ENSP00000504543.1|ensembl:ENSP00000504848.1|ensembl:ENSP00000504198.1|ensembl:ENSP00000503482.1|ensembl:ENSP00000504594.1|ensembl:ENSP00000503419.1"	-	-	-	figure legend:F9 F15|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2025/03/26	rogid:FwuChLb9svxQPVSXV64trbMs7/c334380	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	intact-crc:F5E4E23436719594|rigid:8HbS7BTYC1ZVODgFVgkQDDWaFas	false	necessary binding region:22-121,168-202|flag tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B3CRR2	uniprotkb:Q04206	intact:EBI-26357571	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	psi-mi:b3crr2_oriti(display_long)|uniprotkb:OTT_0753(locus name)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357829|imex:IM-28371-11	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B3CRR2|refseq:WP_012461365.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	-	-	-	figure legend:F15|comment:These results suggest that, while an intact ankyrin repeat domain is required for Ank1 to bind p65, ankyrin repeats two and three functioning in tandem are the most critical.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2025/03/26	rogid:/+kMBD+4JlGdPh2Mxthf507gJIE334380	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:65B3E72D33DCC714|rigid:0CxjQFM0diwp60YAWbdSnxGFWYI	false	flag tag:n-n|necessary binding region:56-121,167-201	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B3CRR2	uniprotkb:O14980	intact:EBI-26357571	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863.2|ensembl:ENSP00000385559.1|ensembl:ENSP00000385942.2|ensembl:ENSP00000503167.1|ensembl:ENSP00000503419.1|ensembl:ENSP00000503482.1|ensembl:ENSP00000503572.1|ensembl:ENSP00000503809.1|ensembl:ENSP00000504087.1|ensembl:ENSP00000504198.1|ensembl:ENSP00000504247.1|ensembl:ENSP00000504543.1|ensembl:ENSP00000504594.1|ensembl:ENSP00000504848.1	psi-mi:b3crr2_oriti(display_long)|uniprotkb:OTT_0753(locus name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357829|imex:IM-28371-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B3CRR2|refseq:WP_012461365.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	"efo:""Orphanet:98838""|ensembl:ENSG00000082898.19(gene)|ensembl:ENST00000401558.7(transcript)|ensembl:ENST00000404992.6(transcript)|ensembl:ENST00000406957.5(transcript)|ensembl:ENST00000676553.1(transcript)|ensembl:ENST00000676667.1(transcript)|ensembl:ENST00000677150.1(transcript)|ensembl:ENST00000677239.1(transcript)|ensembl:ENST00000677417.1(transcript)|ensembl:ENST00000677813.1(transcript)|ensembl:ENST00000677814.1(transcript)|ensembl:ENST00000677928.1(transcript)|ensembl:ENST00000677933.1(transcript)|ensembl:ENST00000678182.1(transcript)|ensembl:ENST00000678790.1(transcript)|go:""GO:0000054""(ribosomal subunit export from nucleus)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0000776""(kinetochore)|go:""GO:0003723""(RNA binding)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005642""(annulate lamellae)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015030""(Cajal body)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032434""(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|interpro:IPR045065|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|rcsb pdb:7B51|rcsb pdb:9B62|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|reactome:R-HSA-9768919|reactome:R-HSA-9828806|reactome:R-HSA-9856649|refseq:NP_003391.1|refseq:XP_006712157.1|refseq:XP_011531399.1|dip:DIP-33678N|panther:PTHR11223(orthology-group)|ensembl:ENSP00000384863.2|ensembl:ENSP00000385942.2|ensembl:ENSP00000385559.1|ensembl:ENSP00000504247.1|ensembl:ENSP00000503809.1|ensembl:ENSP00000503167.1|ensembl:ENSP00000504087.1|ensembl:ENSP00000503572.1|ensembl:ENSP00000504543.1|ensembl:ENSP00000504848.1|ensembl:ENSP00000504198.1|ensembl:ENSP00000503482.1|ensembl:ENSP00000504594.1|ensembl:ENSP00000503419.1"	-	-	-	figure legend:F15|comment:These results suggest that, while an intact ankyrin repeat domain is required for Ank1 to bind p65, ankyrin repeats two and three functioning in tandem are the most critical.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2025/03/26	rogid:/+kMBD+4JlGdPh2Mxthf507gJIE334380	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	intact-crc:65B3E72D33DCC714|rigid:0CxjQFM0diwp60YAWbdSnxGFWYI	false	flag tag:n-n|necessary binding region:56-121,167-201	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B3CRR2	uniprotkb:Q14974	intact:EBI-26357571	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|ensembl:ENSP00000290158.3|ensembl:ENSP00000464042.2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864	psi-mi:b3crr2_oriti(display_long)|uniprotkb:OTT_0753(locus name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Evans et al. (2018)	imex:IM-28371|pubmed:29734393	"taxid:334380(Rickettsia tsutsugamushi)|taxid:334380(""Orientia tsutsugamushi (strain Ikeda)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26357857|imex:IM-28371-13	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:B3CRR2|refseq:WP_012461365.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR018272	"ensembl:ENSG00000108424.11(gene)|ensembl:ENST00000290158.9(transcript)|ensembl:ENST00000583648.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006404""(RNA import into nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0006610""(ribosomal protein import into nucleus)|go:""GO:0007079""(mitotic chromosome movement towards spindle pole)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035580""(specific granule lumen)|go:""GO:0040001""(establishment of mitotic spindle localization)|go:""GO:0042564""(NLS-dependent protein nuclear import complex)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:8GCN|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-68616|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249|reactome:R-HSA-9692916|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|panther:PTHR10527(orthology-group)"	-	-	-	"figure legend:F15|comment:""\""With the exception of ankyrin repeat 1, Flag-tagged Ank1 required an intact ankyrin repeat domain and the ISR to optimally interact with importin β1 (Fig 15).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/23	2024/11/07	rogid:/+kMBD+4JlGdPh2Mxthf507gJIE334380	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	intact-crc:D1CAECF815B3658B|rigid:krmkMhqoKimGh2cnycI99QbUhBA	false	sufficient binding region:56-157,167-201|flag tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P18206	uniprotkb:B0BXR4	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	intact:EBI-26356597	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	psi-mi:b0bxr4_ricro(display_long)|uniprotkb:Protein PS 120(gene name synonym)|uniprotkb:RrIowa_0797(locus name)|uniprotkb:120 kDa antigen(gene name synonym)	"psi-mi:""MI:0404""(comigration in non denaturing gel electrophoresis)"	Park et al. (2011)	imex:IM-28367|pubmed:21841197	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:452659(""Rickettsia rickettsii (strain Iowa)"")|taxid:452659(""Rickettsia rickettsii (strain Iowa)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26356594|imex:IM-28367-1	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	"go:""GO:0005737""(cytoplasm)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:4LQ8|mint:B0BXR4|interpro:IPR020954"	-	-	-	figure legend:fig.1b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/24	2025/02/28	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	rogid:R0jw7TMXduV9zNPEwqzvax73Kdo452659	intact-crc:6E3A171DA012F610|rigid:AWCsBluivQ6HglsvQ5JZk+g9EhU	false	sufficient binding region:1-258	sufficient binding region:774-1008|sufficient binding region:411-585	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:P18206	uniprotkb:B0BXR4	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	intact:EBI-26356597	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	psi-mi:b0bxr4_ricro(display_long)|uniprotkb:Protein PS 120(gene name synonym)|uniprotkb:RrIowa_0797(locus name)|uniprotkb:120 kDa antigen(gene name synonym)	"psi-mi:""MI:0404""(comigration in non denaturing gel electrophoresis)"	Park et al. (2011)	imex:IM-28367|pubmed:21841197	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:452659(""Rickettsia rickettsii (strain Iowa)"")|taxid:452659(""Rickettsia rickettsii (strain Iowa)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26356611|imex:IM-28367-3	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	"go:""GO:0005737""(cytoplasm)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:4LQ8|mint:B0BXR4|interpro:IPR020954"	-	-	-	figure legend:fig. 1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/24	2025/02/28	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	rogid:R0jw7TMXduV9zNPEwqzvax73Kdo452659	intact-crc:78B52EB1A7ACEB34|rigid:AWCsBluivQ6HglsvQ5JZk+g9EhU	false	binding-associated region:1-258	maltose binding protein tag:?-?|binding-associated region:413-431|binding-associated region:814-832	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:B0BXR4	uniprotkb:P18206	intact:EBI-26356597	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:b0bxr4_ricro(display_long)|uniprotkb:Protein PS 120(gene name synonym)|uniprotkb:RrIowa_0797(locus name)|uniprotkb:120 kDa antigen(gene name synonym)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0404""(comigration in non denaturing gel electrophoresis)"	Park et al. (2011)	imex:IM-28367|pubmed:21841197	"taxid:452659(""Rickettsia rickettsii (strain Iowa)"")|taxid:452659(""Rickettsia rickettsii (strain Iowa)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26356802|imex:IM-28367-5	intact-miscore:0.65	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0503""(self)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:4LQ8|mint:B0BXR4|interpro:IPR020954"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	-	-	-	"figure legend:fig. 2a|comment:""\""Indeed, native gel analyses  showed that the nearly full-length sca4 (residues 21–1008) as  well as the domains harboring the VBSs (residues 411–585 and  774–1008) readily displaced the Vt tail domain from pre-existing Vh1Vt complexes by forming a new Vh1sca4-VBS complex (Fig. 2A).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/24	2025/02/28	rogid:R0jw7TMXduV9zNPEwqzvax73Kdo452659	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:07F7F27610B9D375|rigid:AWCsBluivQ6HglsvQ5JZk+g9EhU	false	binding-associated region:774-1008,411-585	binding-associated region:879-1134	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:B0BXR4	uniprotkb:P18206	intact:EBI-26356597	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:b0bxr4_ricro(display_long)|uniprotkb:Protein PS 120(gene name synonym)|uniprotkb:RrIowa_0797(locus name)|uniprotkb:120 kDa antigen(gene name synonym)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0404""(comigration in non denaturing gel electrophoresis)"	Park et al. (2011)	imex:IM-28367|pubmed:21841197	"taxid:452659(""Rickettsia rickettsii (strain Iowa)"")|taxid:452659(""Rickettsia rickettsii (strain Iowa)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26356802|imex:IM-28367-5	intact-miscore:0.65	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0503""(self)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:4LQ8|mint:B0BXR4|interpro:IPR020954"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	-	-	-	"figure legend:fig. 2a|comment:""\""Indeed, native gel analyses  showed that the nearly full-length sca4 (residues 21–1008) as  well as the domains harboring the VBSs (residues 411–585 and  774–1008) readily displaced the Vt tail domain from pre-existing Vh1Vt complexes by forming a new Vh1sca4-VBS complex (Fig. 2A).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/24	2025/02/28	rogid:R0jw7TMXduV9zNPEwqzvax73Kdo452659	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:07F7F27610B9D375|rigid:AWCsBluivQ6HglsvQ5JZk+g9EhU	false	binding-associated region:774-1008,411-585	binding-associated region:1-258	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:B0BXR4	uniprotkb:P18206	intact:EBI-26356597	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:b0bxr4_ricro(display_long)|uniprotkb:Protein PS 120(gene name synonym)|uniprotkb:RrIowa_0797(locus name)|uniprotkb:120 kDa antigen(gene name synonym)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0114""(x-ray crystallography)"	Park et al. (2011)	imex:IM-28367|pubmed:21841197	"taxid:452659(""Rickettsia rickettsii (strain Iowa)"")|taxid:452659(""Rickettsia rickettsii (strain Iowa)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26356850|imex:IM-28367-9	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:4LQ8|mint:B0BXR4|interpro:IPR020954"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	pdbe:3TJ5	-	-	figure legend:table 1,2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/24	2025/02/28	rogid:R0jw7TMXduV9zNPEwqzvax73Kdo452659	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:940553CD6140A353|rigid:AWCsBluivQ6HglsvQ5JZk+g9EhU	false	binding-associated region:412-434	binding-associated region:1-258	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B0BXR4	uniprotkb:P18206	intact:EBI-26356597	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:b0bxr4_ricro(display_long)|uniprotkb:Protein PS 120(gene name synonym)|uniprotkb:RrIowa_0797(locus name)|uniprotkb:120 kDa antigen(gene name synonym)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0114""(x-ray crystallography)"	Park et al. (2011)	imex:IM-28367|pubmed:21841197	"taxid:452659(""Rickettsia rickettsii (strain Iowa)"")|taxid:452659(""Rickettsia rickettsii (strain Iowa)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26356859|imex:IM-28367-11	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:4LQ8|mint:B0BXR4|interpro:IPR020954"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	pdbe:3TJ6	-	-	figure legend:table 1,2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/24	2025/02/28	rogid:R0jw7TMXduV9zNPEwqzvax73Kdo452659	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:9892358158829071|rigid:AWCsBluivQ6HglsvQ5JZk+g9EhU	false	binding-associated region:812-835	binding-associated region:1-258	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B0BXR4	uniprotkb:P18206	intact:EBI-26356597	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:b0bxr4_ricro(display_long)|uniprotkb:Protein PS 120(gene name synonym)|uniprotkb:RrIowa_0797(locus name)|uniprotkb:120 kDa antigen(gene name synonym)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0071""(molecular sieving)"	Park et al. (2011)	imex:IM-28367|pubmed:21841197	"taxid:452659(""Rickettsia rickettsii (strain Iowa)"")|taxid:452659(""Rickettsia rickettsii (strain Iowa)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26356876|imex:IM-28367-13	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:4LQ8|mint:B0BXR4|interpro:IPR020954"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	-	-	-	figure legend:suppl. fig. 1,2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/24	2025/02/28	rogid:R0jw7TMXduV9zNPEwqzvax73Kdo452659	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:3AC05BA35AC22F0D|rigid:AWCsBluivQ6HglsvQ5JZk+g9EhU	false	binding-associated region:411-1008	binding-associated region:1-258	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0H3MBG2	uniprotkb:P63172	intact:EBI-26359442	intact:EBI-1176455|uniprotkb:Q15763|uniprotkb:Q5VTU4|ensembl:ENSP00000356056.3	psi-mi:a0a0h3mbg2_chlt2(display_long)|uniprotkb:CTL0223(locus name)	psi-mi:dylt1_human(display_long)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym)|uniprotkb:Protein CW-1(gene name synonym)|uniprotkb:DYNLT1(gene name)|psi-mi:DYNLT1(display_short)|uniprotkb:TCTEL1(gene name synonym)|uniprotkb:TCTEX1(gene name synonym)|uniprotkb:TCTEX-1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Mital et al. (2015)	pubmed:25944661|imex:IM-28380	"taxid:471472(chlt2)|taxid:471472(""Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359449|imex:IM-28380-1	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|mint:A0A0H3MBG2|refseq:WP_009873457.1|refseq:YP_001654313.1"	"refseq:NP_006510.1|panther:PTHR21255(orthology-group)|dip:DIP-35251N|ensembl:ENSG00000146425.11(gene)|ensembl:ENST00000367089.8(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007399""(nervous system development)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0019060""(intracellular transport of viral protein in host cell)|go:""GO:0030286""(dynein complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043657""(host cell)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051301""(cell division)|go:""GO:0075521""(microtubule-dependent intracellular transport of viral material towards nucleus)|go:""GO:0099503""(secretory vesicle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|mint:P63172|rcsb pdb:5JPW|rcsb pdb:8J07|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGI|reactome:R-HSA-6798695"	-	-	-	figure legend:nfa|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/09/25	2025/02/28	rogid:Av5SaOpnI7Dq1oDrDOnTGbE1+7w471472	rogid:RKVyHgf4iNjcY6GfLdIukFOFE+s9606	intact-crc:7194EBFEF241EAA5|rigid:vOJpYC4WZ/qNRvmXf2i9wo/l6YU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H3MBG2	uniprotkb:P63172	intact:EBI-26359442	intact:EBI-1176455|uniprotkb:Q15763|uniprotkb:Q5VTU4|ensembl:ENSP00000356056.3	psi-mi:a0a0h3mbg2_chlt2(display_long)|uniprotkb:CTL0223(locus name)	psi-mi:dylt1_human(display_long)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym)|uniprotkb:Protein CW-1(gene name synonym)|uniprotkb:DYNLT1(gene name)|psi-mi:DYNLT1(display_short)|uniprotkb:TCTEL1(gene name synonym)|uniprotkb:TCTEX1(gene name synonym)|uniprotkb:TCTEX-1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Mital et al. (2015)	pubmed:25944661|imex:IM-28380	"taxid:471472(chlt2)|taxid:471472(""Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359453|imex:IM-28380-3	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|mint:A0A0H3MBG2|refseq:WP_009873457.1|refseq:YP_001654313.1"	"refseq:NP_006510.1|panther:PTHR21255(orthology-group)|dip:DIP-35251N|ensembl:ENSG00000146425.11(gene)|ensembl:ENST00000367089.8(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007399""(nervous system development)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0019060""(intracellular transport of viral protein in host cell)|go:""GO:0030286""(dynein complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043657""(host cell)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051301""(cell division)|go:""GO:0075521""(microtubule-dependent intracellular transport of viral material towards nucleus)|go:""GO:0099503""(secretory vesicle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|mint:P63172|rcsb pdb:5JPW|rcsb pdb:8J07|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGI|reactome:R-HSA-6798695"	-	-	-	figure legend:f1a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/09/25	2025/02/28	rogid:Av5SaOpnI7Dq1oDrDOnTGbE1+7w471472	rogid:RKVyHgf4iNjcY6GfLdIukFOFE+s9606	intact-crc:97F46370EC0BF589|rigid:vOJpYC4WZ/qNRvmXf2i9wo/l6YU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0H3MBG2	uniprotkb:P63172	intact:EBI-26359442	intact:EBI-1176455|uniprotkb:Q15763|uniprotkb:Q5VTU4|ensembl:ENSP00000356056.3	psi-mi:a0a0h3mbg2_chlt2(display_long)|uniprotkb:CTL0223(locus name)	psi-mi:dylt1_human(display_long)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym)|uniprotkb:Protein CW-1(gene name synonym)|uniprotkb:DYNLT1(gene name)|psi-mi:DYNLT1(display_short)|uniprotkb:TCTEL1(gene name synonym)|uniprotkb:TCTEX1(gene name synonym)|uniprotkb:TCTEX-1(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Mital et al. (2015)	pubmed:25944661|imex:IM-28380	"taxid:471472(chlt2)|taxid:471472(""Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359474|imex:IM-28380-5	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|mint:A0A0H3MBG2|refseq:WP_009873457.1|refseq:YP_001654313.1"	"refseq:NP_006510.1|panther:PTHR21255(orthology-group)|dip:DIP-35251N|ensembl:ENSG00000146425.11(gene)|ensembl:ENST00000367089.8(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007399""(nervous system development)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0019060""(intracellular transport of viral protein in host cell)|go:""GO:0030286""(dynein complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043657""(host cell)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051301""(cell division)|go:""GO:0075521""(microtubule-dependent intracellular transport of viral material towards nucleus)|go:""GO:0099503""(secretory vesicle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|mint:P63172|rcsb pdb:5JPW|rcsb pdb:8J07|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGI|reactome:R-HSA-6798695"	-	-	-	figure legend:f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/25	2025/02/28	rogid:Av5SaOpnI7Dq1oDrDOnTGbE1+7w471472	rogid:RKVyHgf4iNjcY6GfLdIukFOFE+s9606	intact-crc:5A74AC8E7B16E09C|rigid:vOJpYC4WZ/qNRvmXf2i9wo/l6YU	false	mcherry fluorescent protein tag:c-c	green fluorescent protein tag:c-c	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3MBG2	uniprotkb:P63172	intact:EBI-26359442	intact:EBI-1176455|uniprotkb:Q15763|uniprotkb:Q5VTU4|ensembl:ENSP00000356056.3	psi-mi:a0a0h3mbg2_chlt2(display_long)|uniprotkb:CTL0223(locus name)	psi-mi:dylt1_human(display_long)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym)|uniprotkb:Protein CW-1(gene name synonym)|uniprotkb:DYNLT1(gene name)|psi-mi:DYNLT1(display_short)|uniprotkb:TCTEL1(gene name synonym)|uniprotkb:TCTEX1(gene name synonym)|uniprotkb:TCTEX-1(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Mital et al. (2015)	pubmed:25944661|imex:IM-28380	"taxid:471472(chlt2)|taxid:471472(""Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359501|imex:IM-28380-7	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|mint:A0A0H3MBG2|refseq:WP_009873457.1|refseq:YP_001654313.1"	"refseq:NP_006510.1|panther:PTHR21255(orthology-group)|dip:DIP-35251N|ensembl:ENSG00000146425.11(gene)|ensembl:ENST00000367089.8(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007399""(nervous system development)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0019060""(intracellular transport of viral protein in host cell)|go:""GO:0030286""(dynein complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043657""(host cell)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051301""(cell division)|go:""GO:0075521""(microtubule-dependent intracellular transport of viral material towards nucleus)|go:""GO:0099503""(secretory vesicle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|mint:P63172|rcsb pdb:5JPW|rcsb pdb:8J07|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGI|reactome:R-HSA-6798695"	"go:""GO:0016234""(inclusion body)"	-	-	figure legend:f3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/25	2025/02/28	rogid:Av5SaOpnI7Dq1oDrDOnTGbE1+7w471472	rogid:RKVyHgf4iNjcY6GfLdIukFOFE+s9606	intact-crc:0A0BD5C48C708281|rigid:vOJpYC4WZ/qNRvmXf2i9wo/l6YU	false	-	green fluorescent protein tag:c-c	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:A0A0H3MBG2	uniprotkb:P63172	intact:EBI-26359442	intact:EBI-1176455|uniprotkb:Q15763|uniprotkb:Q5VTU4|ensembl:ENSP00000356056.3	psi-mi:a0a0h3mbg2_chlt2(display_long)|uniprotkb:CTL0223(locus name)	psi-mi:dylt1_human(display_long)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym)|uniprotkb:Protein CW-1(gene name synonym)|uniprotkb:DYNLT1(gene name)|psi-mi:DYNLT1(display_short)|uniprotkb:TCTEL1(gene name synonym)|uniprotkb:TCTEX1(gene name synonym)|uniprotkb:TCTEX-1(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Mital et al. (2015)	pubmed:25944661|imex:IM-28380	"taxid:471472(chlt2)|taxid:471472(""Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359518|imex:IM-28380-9	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|mint:A0A0H3MBG2|refseq:WP_009873457.1|refseq:YP_001654313.1"	"refseq:NP_006510.1|panther:PTHR21255(orthology-group)|dip:DIP-35251N|ensembl:ENSG00000146425.11(gene)|ensembl:ENST00000367089.8(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007399""(nervous system development)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0019060""(intracellular transport of viral protein in host cell)|go:""GO:0030286""(dynein complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043657""(host cell)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051301""(cell division)|go:""GO:0075521""(microtubule-dependent intracellular transport of viral material towards nucleus)|go:""GO:0099503""(secretory vesicle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|mint:P63172|rcsb pdb:5JPW|rcsb pdb:8J07|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGI|reactome:R-HSA-6798695"	-	-	-	figure legend:f2a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/25	2025/02/28	rogid:Av5SaOpnI7Dq1oDrDOnTGbE1+7w471472	rogid:RKVyHgf4iNjcY6GfLdIukFOFE+s9606	intact-crc:15ACA35FE6F0C205|rigid:vOJpYC4WZ/qNRvmXf2i9wo/l6YU	false	mcherry fluorescent protein tag:c-c	green fluorescent protein tag:c-c	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:Q5ZXN6	uniprotkb:Q494U1	intact:EBI-26359852	intact:EBI-10241513|ensembl:ENSP00000368720.3|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	"psi-mi:""MI:0089""(protein array)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359874|imex:IM-28385-41	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"ensembl:ENSG00000187583.11(gene)|ensembl:ENST00000379410.8(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1901981""(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|mint:Q494U1|refseq:NP_001153656.1|refseq:NP_115505.2|panther:PTHR46882(orthology-group)"	-	-	-	figure legend:f1b f1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	intact-crc:A3C4A84DFAA7F1B1|rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	fluorescent protein tag:c-c	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q86WP2	intact:EBI-26359852	intact:EBI-2349758|ensembl:ENSP00000421202.2|uniprotkb:A6NKW3|uniprotkb:Q6NSH6|uniprotkb:Q9H785|uniprotkb:Q9H0D4|uniprotkb:Q9NSN4|intact:EBI-28972285	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:gpbp1_human(display_long)|uniprotkb:GPBP1(gene name)|psi-mi:GPBP1(display_short)|uniprotkb:GPBP(gene name synonym)|uniprotkb:SSH6(gene name synonym)|uniprotkb:GC-rich promoter-binding protein 1(gene name synonym)|uniprotkb:Vascular wall-linked protein(gene name synonym)	"psi-mi:""MI:0089""(protein array)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359945|imex:IM-28385-43	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"ensembl:ENSG00000062194.16(gene)|ensembl:ENST00000506184.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR028128|mint:Q86WP2|refseq:NP_001120707.2|refseq:NP_001120708.1|refseq:NP_001190175.1|refseq:NP_075064.1|refseq:XP_016865245.1|refseq:XP_016865246.1|refseq:XP_016865247.1|refseq:XP_016865248.1|panther:PTHR14339(orthology-group)"	-	-	-	figure legend:f1b f1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:YpnFRXC1FDOxqNl2Dq67tJRNO6o9606	intact-crc:9443489723C4D93E|rigid:yoCB7W4qY4K+QGhpLysXJUQnOYo	false	fluorescent protein tag:c-c	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:P98187	intact:EBI-26359852	intact:EBI-1049983|ensembl:ENSP00000477567.1	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:cp4f8_human(display_long)|uniprotkb:CYPIVF8(gene name synonym)|uniprotkb:CYP4F8(gene name)|psi-mi:CYP4F8(display_short)	"psi-mi:""MI:0089""(protein array)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359954|imex:IM-28385-21	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"refseq:NP_009184.1|ensembl:ENSG00000186526.13(gene)|ensembl:ENST00000612078.5(transcript)|go:""GO:0004497""(monooxygenase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006690""(icosanoid metabolic process)|go:""GO:0006693""(prostaglandin metabolic process)|go:""GO:0016712""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:""GO:0018685""(alkane 1-monooxygenase activity)|go:""GO:0020037""(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR036396|interpro:IPR050196|mint:P98187|reactome:R-HSA-211935|reactome:R-HSA-211979|reactome:R-HSA-2142691|panther:PTHR24291(orthology-group)"	-	-	-	figure legend:f1b f1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:Um8FlQYWmjdBW61eG5LNPDdBaW89606	intact-crc:FEF8628A39EB5F67|rigid:JgQoImfijVJ7Z+lN2b3n6JkoKLc	false	fluorescent protein tag:c-c	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q9H4M7	intact:EBI-26359852	intact:EBI-716549|uniprotkb:Q8N4M8|uniprotkb:Q8N658|ensembl:ENSP00000263265.5	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:pkha4_human(display_long)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 1(gene name synonym)|uniprotkb:PLEKHA4(gene name)|psi-mi:PLEKHA4(display_short)|uniprotkb:PEPP1(gene name synonym)	"psi-mi:""MI:0089""(protein array)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359964|imex:IM-28385-1	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"refseq:NP_001154826.1|refseq:NP_065955.2|ensembl:ENSG00000105559.13(gene)|ensembl:ENST00000263265.11(transcript)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043325""(phosphatidylinositol-3,4-bisphosphate binding)|go:""GO:0080025""(phosphatidylinositol-3,5-bisphosphate binding)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:2000096""(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR040392|mint:Q9H4M7|rcsb pdb:1UPQ|rcsb pdb:1UPR|rcsb pdb:8OIO|reactome:R-HSA-1660499|panther:PTHR12752(orthology-group)"	-	-	-	figure legend:f1b f1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:gBeBdIcJIF2fJe6r+Ea2gmiKiTQ9606	intact-crc:0674B2A35E3BAEEC|rigid:4j4JG3yIkSI9dmUv8ce3lOioauU	false	fluorescent protein tag:c-c	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q8N3F8	intact:EBI-26359852	intact:EBI-1056885|uniprotkb:Q5TI16|uniprotkb:Q7RTP5|uniprotkb:Q8N3N8|uniprotkb:Q9BVL9|uniprotkb:Q9BY92|uniprotkb:Q9UH43|uniprotkb:Q9UH44|uniprotkb:Q9UH45|ensembl:ENSP00000215957.6	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:milk1_human(display_long)|uniprotkb:MICALL1(gene name)|psi-mi:MICALL1(display_short)|uniprotkb:KIAA1668(gene name synonym)|uniprotkb:MIRAB13(gene name synonym)|uniprotkb:Molecule interacting with Rab13(gene name synonym)	"psi-mi:""MI:0089""(protein array)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359973|imex:IM-28385-3	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"refseq:NP_203744.1|ensembl:ENSG00000100139.14(gene)|ensembl:ENST00000215957.10(transcript)|go:""GO:0005770""(late endosome)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0010009""(cytoplasmic side of endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032458""(slow endocytic recycling)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:0097320""(plasma membrane tubulation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR022735|interpro:IPR036872|interpro:IPR050540|mint:Q8N3F8|rcsb pdb:2KSP"	-	-	-	figure legend:f1b f1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:G64P9EtjEfLIVLYkb+w3vCWaT0w9606	intact-crc:D1CA8A5856D7FDCB|rigid:PdqN5Q9YlDA7F6QLubEzzeNF/0I	false	fluorescent protein tag:c-c	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:P22694	intact:EBI-26359852	intact:EBI-2679622|uniprotkb:Q59GC0|uniprotkb:Q5BNF2|uniprotkb:Q8IYR5|uniprotkb:Q14VH1|uniprotkb:Q5BNF3|uniprotkb:Q96B09|uniprotkb:Q8IZQ0|uniprotkb:Q5BNE9|uniprotkb:B4E2Q1|uniprotkb:Q7Z3M1|uniprotkb:Q5BNF1|uniprotkb:Q5CZ92|uniprotkb:Q5T1K3|uniprotkb:Q5BNF0|uniprotkb:B4DKB0|uniprotkb:B1APG4|ensembl:ENSP00000359723.2	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:kapcb_human(display_long)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short)	"psi-mi:""MI:0089""(protein array)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359983|imex:IM-28385-45	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"efo:""Orphanet:289""|ensembl:ENSG00000142875.21(gene)|ensembl:ENST00000370689.6(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003091""(renal water homeostasis)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004691""(cAMP-dependent protein kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0007188""(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034380""(high-density lipoprotein particle assembly)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070613""(regulation of protein processing)|go:""GO:0097546""(ciliary base)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P22694|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8963896|reactome:R-HSA-9010642|reactome:R-HSA-9634597|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9856530|refseq:NP_001229786.1|refseq:NP_001229787.1|refseq:NP_001229788.1|refseq:NP_001229789.1|refseq:NP_001229790.1|refseq:NP_001229791.1|refseq:NP_001287844.1|refseq:NP_001287845.1|refseq:NP_001287846.1|refseq:NP_002722.1|refseq:NP_891993.1|refseq:NP_997461.1|refseq:XP_005271076.1|refseq:XP_006710821.1|panther:PTHR24353(orthology-group)"	-	-	-	figure legend:f1b f1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:FEzsjRJZlkFu5+KK4abzu7oAY9E9606	intact-crc:A37735B8C3E2FAE1|rigid:Z46Kic97YEwgZpQB7Chbbt2DGCQ	false	fluorescent protein tag:c-c	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q16643	intact:EBI-26359852	intact:EBI-351394|uniprotkb:Q9UFZ5|uniprotkb:B2RBG0|intact:EBI-4404710|uniprotkb:A8MV58|ensembl:ENSP00000308532.5	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:dreb_human(display_long)|uniprotkb:DBN1(gene name)|psi-mi:DBN1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:D0S117E(gene name synonym)	"psi-mi:""MI:0089""(protein array)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359991|imex:IM-28385-23	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"refseq:NP_004386.2|refseq:NP_543157.1|refseq:XP_005265884.1|ensembl:ENSG00000113758.14(gene)|ensembl:ENST00000309007.9(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005921""(gap junction)|go:""GO:0007015""(actin filament organization)|go:""GO:0010643""(cell communication by chemical coupling)|go:""GO:0010644""(cell communication by electrical coupling)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0031915""(positive regulation of synaptic plasticity)|go:""GO:0032507""(maintenance of protein location in cell)|go:""GO:0042641""(actomyosin)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0048168""(regulation of neuronal synaptic plasticity)|go:""GO:0048699""(generation of neurons)|go:""GO:0050773""(regulation of dendrite development)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0061351""(neural precursor cell proliferation)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:1902685""(positive regulation of receptor localization to synapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|mint:Q16643|rcsb pdb:5Y1Z|rcsb pdb:5ZZ9|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:XP_016864629.1"	-	-	-	figure legend:f1b f1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:0+VPJM5mTuG2jzmzGG3iLswmCUc9606	intact-crc:5ABDEB3ACA768319|rigid:CGwPknqU4eHKHXnRabmn3CoiTzI	false	fluorescent protein tag:c-c	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q8TBK6	intact:EBI-26359852	intact:EBI-597063|uniprotkb:Q9NXR4|ensembl:ENSP00000423276.1	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:zch10_human(display_long)|uniprotkb:ZCCHC10(gene name)|psi-mi:ZCCHC10(display_short)	"psi-mi:""MI:0089""(protein array)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26359999|imex:IM-28385-5	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"refseq:NP_060135.1|ensembl:ENSG00000155329.12(gene)|ensembl:ENST00000509437.6(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0008270""(zinc ion binding)|interpro:IPR036875|interpro:IPR039715|mint:Q8TBK6|refseq:NP_001287746.1|refseq:NP_001287747.1|refseq:NP_001287748.1|refseq:NP_001287751.1|refseq:NP_001295056.1|refseq:NP_001295057.1|refseq:NP_001295058.1|refseq:NP_001295059.1|refseq:NP_001287745.1|panther:PTHR13491(orthology-group)"	-	-	-	figure legend:f1b f1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:WcCfa6tnoaA9NGta4vXKUY3VnxI9606	intact-crc:4A2D7328A9439052|rigid:cs0Xb4fA7s1jnHDY4jttm7GTZsw	false	fluorescent protein tag:c-c	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q494U1	uniprotkb:Q5ZWZ3	intact:EBI-10241513|ensembl:ENSP00000368720.3|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2	intact:EBI-6417967	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:q5zwz3_legph(display_long)|uniprotkb:lpg0940(locus name)	"psi-mi:""MI:0089""(protein array)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26361239|imex:IM-28385-53	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000187583.11(gene)|ensembl:ENST00000379410.8(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1901981""(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|mint:Q494U1|refseq:NP_001153656.1|refseq:NP_115505.2|panther:PTHR46882(orthology-group)"	interpro:IPR041463|rcsb pdb:3TNF|refseq:WP_010946675.1|dip:DIP-59799N|mint:Q5ZWZ3|refseq:YP_094974.1	-	-	-	figure legend:SF7|comment:Positive control|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rogid:AyBH7iPqbJYlEKGIubXHtBV/M+U272624	intact-crc:DDF4AD3EF576B7B5|rigid:vBRez76pwvRXUdBfCMRqcGGFEao	false	fluorescent protein tag:c-c	glutathione s tranferase tag:c-c	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q494U1	intact:EBI-26359852	intact:EBI-10241513|ensembl:ENSP00000368720.3|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26360575|imex:IM-28385-7	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"ensembl:ENSG00000187583.11(gene)|ensembl:ENST00000379410.8(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1901981""(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|mint:Q494U1|refseq:NP_001153656.1|refseq:NP_115505.2|panther:PTHR46882(orthology-group)"	-	-	-	figure legend:f2a f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	intact-crc:B1BDCC43099D2B6E|rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	fluorescent protein tag:c-c	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q86WP2	intact:EBI-26359852	intact:EBI-2349758|ensembl:ENSP00000421202.2|uniprotkb:A6NKW3|uniprotkb:Q6NSH6|uniprotkb:Q9H785|uniprotkb:Q9H0D4|uniprotkb:Q9NSN4|intact:EBI-28972285	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:gpbp1_human(display_long)|uniprotkb:GPBP1(gene name)|psi-mi:GPBP1(display_short)|uniprotkb:GPBP(gene name synonym)|uniprotkb:SSH6(gene name synonym)|uniprotkb:GC-rich promoter-binding protein 1(gene name synonym)|uniprotkb:Vascular wall-linked protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26360608|imex:IM-28385-9	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"ensembl:ENSG00000062194.16(gene)|ensembl:ENST00000506184.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR028128|mint:Q86WP2|refseq:NP_001120707.2|refseq:NP_001120708.1|refseq:NP_001190175.1|refseq:NP_075064.1|refseq:XP_016865245.1|refseq:XP_016865246.1|refseq:XP_016865247.1|refseq:XP_016865248.1|panther:PTHR14339(orthology-group)"	-	-	-	figure legend:f2a f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:YpnFRXC1FDOxqNl2Dq67tJRNO6o9606	intact-crc:D4937DF0D198B950|rigid:yoCB7W4qY4K+QGhpLysXJUQnOYo	false	fluorescent protein tag:c-c	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q8TBK6	intact:EBI-26359852	intact:EBI-597063|uniprotkb:Q9NXR4|ensembl:ENSP00000423276.1	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:zch10_human(display_long)|uniprotkb:ZCCHC10(gene name)|psi-mi:ZCCHC10(display_short)	"psi-mi:""MI:0096""(pull down)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26360616|imex:IM-28385-25	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"refseq:NP_060135.1|ensembl:ENSG00000155329.12(gene)|ensembl:ENST00000509437.6(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0008270""(zinc ion binding)|interpro:IPR036875|interpro:IPR039715|mint:Q8TBK6|refseq:NP_001287746.1|refseq:NP_001287747.1|refseq:NP_001287748.1|refseq:NP_001287751.1|refseq:NP_001295056.1|refseq:NP_001295057.1|refseq:NP_001295058.1|refseq:NP_001295059.1|refseq:NP_001287745.1|panther:PTHR13491(orthology-group)"	-	-	-	figure legend:f2a f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:WcCfa6tnoaA9NGta4vXKUY3VnxI9606	intact-crc:FC8BD6F06D02CAB6|rigid:cs0Xb4fA7s1jnHDY4jttm7GTZsw	false	fluorescent protein tag:c-c	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q8N3F8	intact:EBI-26359852	intact:EBI-1056885|uniprotkb:Q5TI16|uniprotkb:Q7RTP5|uniprotkb:Q8N3N8|uniprotkb:Q9BVL9|uniprotkb:Q9BY92|uniprotkb:Q9UH43|uniprotkb:Q9UH44|uniprotkb:Q9UH45|ensembl:ENSP00000215957.6	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:milk1_human(display_long)|uniprotkb:MICALL1(gene name)|psi-mi:MICALL1(display_short)|uniprotkb:KIAA1668(gene name synonym)|uniprotkb:MIRAB13(gene name synonym)|uniprotkb:Molecule interacting with Rab13(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26360624|imex:IM-28385-27	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"refseq:NP_203744.1|ensembl:ENSG00000100139.14(gene)|ensembl:ENST00000215957.10(transcript)|go:""GO:0005770""(late endosome)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0010009""(cytoplasmic side of endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032458""(slow endocytic recycling)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:0097320""(plasma membrane tubulation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR022735|interpro:IPR036872|interpro:IPR050540|mint:Q8N3F8|rcsb pdb:2KSP"	-	-	-	figure legend:f2a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:G64P9EtjEfLIVLYkb+w3vCWaT0w9606	intact-crc:076B35B7D6891327|rigid:PdqN5Q9YlDA7F6QLubEzzeNF/0I	false	fluorescent protein tag:c-c	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q9H4M7	intact:EBI-26359852	intact:EBI-716549|uniprotkb:Q8N4M8|uniprotkb:Q8N658|ensembl:ENSP00000263265.5	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:pkha4_human(display_long)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 1(gene name synonym)|uniprotkb:PLEKHA4(gene name)|psi-mi:PLEKHA4(display_short)|uniprotkb:PEPP1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26360632|imex:IM-28385-29	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"refseq:NP_001154826.1|refseq:NP_065955.2|ensembl:ENSG00000105559.13(gene)|ensembl:ENST00000263265.11(transcript)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043325""(phosphatidylinositol-3,4-bisphosphate binding)|go:""GO:0080025""(phosphatidylinositol-3,5-bisphosphate binding)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:2000096""(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR040392|mint:Q9H4M7|rcsb pdb:1UPQ|rcsb pdb:1UPR|rcsb pdb:8OIO|reactome:R-HSA-1660499|panther:PTHR12752(orthology-group)"	-	-	-	figure legend:f2a f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:gBeBdIcJIF2fJe6r+Ea2gmiKiTQ9606	intact-crc:BC7CE7D21A3DAFB5|rigid:4j4JG3yIkSI9dmUv8ce3lOioauU	false	fluorescent protein tag:c-c	glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q494U1	intact:EBI-26359852	intact:EBI-10241513|ensembl:ENSP00000368720.3|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26360640|imex:IM-28385-31	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"ensembl:ENSG00000187583.11(gene)|ensembl:ENST00000379410.8(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1901981""(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|mint:Q494U1|refseq:NP_001153656.1|refseq:NP_115505.2|panther:PTHR46882(orthology-group)"	-	-	-	figure legend:f3a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	intact-crc:55C9D0F326D4C1E4|rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	glutathione s tranferase tag:n-n	fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZXN6	uniprotkb:Q494U1	intact:EBI-26359852	intact:EBI-10241513|ensembl:ENSP00000368720.3|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26360858|imex:IM-28385-33	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"ensembl:ENSG00000187583.11(gene)|ensembl:ENST00000379410.8(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1901981""(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|mint:Q494U1|refseq:NP_001153656.1|refseq:NP_115505.2|panther:PTHR46882(orthology-group)"	-	-	-	figure legend:f3b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	intact-crc:A59C0BA0DBCFDA91|rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	glutathione s tranferase tag:n-n	fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q5ZXN6	uniprotkb:Q494U1	intact:EBI-26359852	intact:EBI-10241513|ensembl:ENSP00000368720.3|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26361077|imex:IM-28385-47	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"ensembl:ENSG00000187583.11(gene)|ensembl:ENST00000379410.8(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1901981""(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|mint:Q494U1|refseq:NP_001153656.1|refseq:NP_115505.2|panther:PTHR46882(orthology-group)"	-	-	-	figure legend:f3c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	intact-crc:4F1116E023973719|rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	fluorescent protein tag:c-c	green fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q5ZXN6	uniprotkb:Q494U1	intact:EBI-26359852	intact:EBI-10241513|ensembl:ENSP00000368720.3|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26361104|imex:IM-28385-11	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"ensembl:ENSG00000187583.11(gene)|ensembl:ENST00000379410.8(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1901981""(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|mint:Q494U1|refseq:NP_001153656.1|refseq:NP_115505.2|panther:PTHR46882(orthology-group)"	"go:""GO:0005886""(plasma membrane)"	-	-	figure legend:f5|comment:HaloTag-AnkXH229A accumulated less on the plasma membrane|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	intact-crc:506D2137B7842F53|rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	fluorescent protein tag:c-c|mutation decreasing interaction:229-229	-	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q5ZXN6	uniprotkb:Q494U1	intact:EBI-26359852	intact:EBI-10241513|ensembl:ENSP00000368720.3|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26361118|imex:IM-28385-13	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094731.1|go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044605""(phosphocholine transferase activity)|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|rcsb pdb:6SKU|interpro:IPR054037|refseq:WP_010946432.1|mint:Q5ZXN6|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR050016"	"ensembl:ENSG00000187583.11(gene)|ensembl:ENST00000379410.8(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:1901612""(cardiolipin binding)|go:""GO:1901981""(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|mint:Q494U1|refseq:NP_001153656.1|refseq:NP_115505.2|panther:PTHR46882(orthology-group)"	"go:""GO:0005634""(nucleus)"	-	-	figure legend:f6|comment:In turn, the mCherry-AnkX491-809 fragment showed a speckled distribution in the nucleus and extensively co-localized with PLEKHN1.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/09/28	2024/11/14	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	intact-crc:46EFA1AD86307968|rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	mcherry fluorescent protein tag:c-c|binding-associated region:491-809	-	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q5ZRP9	uniprotkb:P51148	intact:EBI-26364295	intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689.5|ensembl:ENSP00000377440.3|intact:EBI-21355794	psi-mi:q5zrp9_legph(display_long)|uniprotkb:vipD(gene name)|psi-mi:vipD(display_short)|uniprotkb:lpg2831(locus name)	psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Lucas et al. (2014)	pubmed:25114243|imex:IM-28402	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26364308|imex:IM-28402-1	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_096826.1|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|rcsb pdb:4AKF|rcsb pdb:4KYI|interpro:IPR054392|mint:Q5ZRP9|refseq:WP_010948518.1|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|interpro:IPR052580"	"refseq:NP_004574.2|refseq:NP_958842.1|refseq:NP_001238968.1|ensembl:ENSG00000108774.15(gene)|ensembl:ENST00000346213.9(transcript)|ensembl:ENST00000393860.7(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0012505""(endomembrane system)|go:""GO:0019003""(GDP binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042470""(melanosome)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51148|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9820960|refseq:XP_011523392.1|refseq:XP_011523393.1|panther:PTHR24073(orthology-group)"	pdbe:4kyi	-	-	"figure legend:f1 f2 t1 sf1|comment:""\""he final model for the VipD19–564-Rab5c18–182(Q80L)-GppNHp structure was refined at 3.1 Å, with values for Rfactor and Rfree of 0.23 and 0.28, respectively\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/05	2024/11/14	rogid:+GMms/JxD2Ftf8LsGcwSINkoIaY272624	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	intact-crc:D5820DC1ECB5CF5B|rigid:4AOfcuQ06NmTWIifJKHTT/wuLwA	false	binding-associated region:19-564	mutation:80-80|binding-associated region:18-182	2	2	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5ZRP9	uniprotkb:P51148	intact:EBI-26364295	intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689.5|ensembl:ENSP00000377440.3|intact:EBI-21355794	psi-mi:q5zrp9_legph(display_long)|uniprotkb:vipD(gene name)|psi-mi:vipD(display_short)|uniprotkb:lpg2831(locus name)	psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Lucas et al. (2014)	pubmed:25114243|imex:IM-28402	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26364339|imex:IM-28402-3	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_096826.1|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|rcsb pdb:4AKF|rcsb pdb:4KYI|interpro:IPR054392|mint:Q5ZRP9|refseq:WP_010948518.1|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|interpro:IPR052580"	"refseq:NP_004574.2|refseq:NP_958842.1|refseq:NP_001238968.1|ensembl:ENSG00000108774.15(gene)|ensembl:ENST00000346213.9(transcript)|ensembl:ENST00000393860.7(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0012505""(endomembrane system)|go:""GO:0019003""(GDP binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042470""(melanosome)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51148|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9820960|refseq:XP_011523392.1|refseq:XP_011523393.1|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:f4a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/05	2024/11/14	rogid:+GMms/JxD2Ftf8LsGcwSINkoIaY272624	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	intact-crc:692D3D90A1700144|rigid:4AOfcuQ06NmTWIifJKHTT/wuLwA	false	mutation disrupting interaction:442-442|glutathione s tranferase tag:n-n|mutation decreasing interaction:449-449|mutation disrupting interaction:453-453|mutation decreasing interaction:461-461|mutation decreasing interaction:473-473|mutation with no effect:476-476|mutation decreasing interaction:479-479|mutation with no effect:484-484	mutation:80-80|binding-associated region:18-182	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q5ZRP9	uniprotkb:P51148	intact:EBI-26364295	intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689.5|ensembl:ENSP00000377440.3|intact:EBI-21355794	psi-mi:q5zrp9_legph(display_long)|uniprotkb:vipD(gene name)|psi-mi:vipD(display_short)|uniprotkb:lpg2831(locus name)	psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Lucas et al. (2014)	pubmed:25114243|imex:IM-28402	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26364372|imex:IM-28402-5	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_096826.1|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|rcsb pdb:4AKF|rcsb pdb:4KYI|interpro:IPR054392|mint:Q5ZRP9|refseq:WP_010948518.1|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|interpro:IPR052580"	"refseq:NP_004574.2|refseq:NP_958842.1|refseq:NP_001238968.1|ensembl:ENSG00000108774.15(gene)|ensembl:ENST00000346213.9(transcript)|ensembl:ENST00000393860.7(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0012505""(endomembrane system)|go:""GO:0019003""(GDP binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042470""(melanosome)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51148|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9820960|refseq:XP_011523392.1|refseq:XP_011523393.1|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:f4b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/05	2024/11/14	rogid:+GMms/JxD2Ftf8LsGcwSINkoIaY272624	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	intact-crc:FE0212AB685461BB|rigid:4AOfcuQ06NmTWIifJKHTT/wuLwA	false	-	mutation disrupting interaction:58-58|mutation with no effect:73-73|mutation decreasing interaction:75-75|mutation decreasing interaction:82-82|mutation disrupting interaction:83-83|mutation decreasing interaction:89-89|mutation with no effect:80-80|binding-associated region:18-182|glutathione s tranferase tag:n-n|mutation with no effect:90-90|mutation disrupting interaction:92-92	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q5ZRP9	uniprotkb:Q9UL26	intact:EBI-26364295	intact:EBI-399456|uniprotkb:Q8TF12|uniprotkb:Q9H4E6|uniprotkb:B3KR86|uniprotkb:E1P605|ensembl:ENSP00000244040.3	psi-mi:q5zrp9_legph(display_long)|uniprotkb:vipD(gene name)|psi-mi:vipD(display_short)|uniprotkb:lpg2831(locus name)	psi-mi:rb22a_human(display_long)|uniprotkb:RAB22A(gene name)|psi-mi:RAB22A(display_short)|uniprotkb:RAB22(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Lucas et al. (2014)	pubmed:25114243|imex:IM-28402	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26364446|imex:IM-28402-7	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_096826.1|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|rcsb pdb:4AKF|rcsb pdb:4KYI|interpro:IPR054392|mint:Q5ZRP9|refseq:WP_010948518.1|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|interpro:IPR052580"	"refseq:NP_065724.1|ensembl:ENSG00000124209.4(gene)|ensembl:ENST00000244040.4(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0007032""(endosome organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0012505""(endomembrane system)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0019003""(GDP binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097494""(regulation of vesicle size)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9UL26|reactome:R-HSA-8873719|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:f4C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/05	2024/11/14	rogid:+GMms/JxD2Ftf8LsGcwSINkoIaY272624	rogid:K6gpzvSza/iYmgPSX0RHLH6y7qM9606	intact-crc:8D2DA63563823F2F|rigid:pNA68tF37DxZHa0qOs5w0vlQxfI	false	mutation disrupting interaction:442-442|glutathione s tranferase tag:n-n|mutation disrupting interaction:449-449|mutation decreasing interaction:453-453|mutation disrupting interaction:461-461|mutation decreasing interaction:473-473|mutation with no effect:476-476|mutation decreasing interaction:479-479|mutation with no effect:484-484	mutation:64-64|binding-associated region:18-182	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q5ZRP9	uniprotkb:P51148	intact:EBI-26364295	intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689.5|ensembl:ENSP00000377440.3|intact:EBI-21355794	psi-mi:q5zrp9_legph(display_long)|uniprotkb:vipD(gene name)|psi-mi:vipD(display_short)|uniprotkb:lpg2831(locus name)	psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Lucas et al. (2014)	pubmed:25114243|imex:IM-28402	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26364594|imex:IM-28402-9	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_096826.1|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|rcsb pdb:4AKF|rcsb pdb:4KYI|interpro:IPR054392|mint:Q5ZRP9|refseq:WP_010948518.1|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|interpro:IPR052580"	"refseq:NP_004574.2|refseq:NP_958842.1|refseq:NP_001238968.1|ensembl:ENSG00000108774.15(gene)|ensembl:ENST00000346213.9(transcript)|ensembl:ENST00000393860.7(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0012505""(endomembrane system)|go:""GO:0019003""(GDP binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042470""(melanosome)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51148|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9820960|refseq:XP_011523392.1|refseq:XP_011523393.1|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:f7b f7c sf6|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.11x10^-6(molar)	2020/10/05	2024/11/14	rogid:+GMms/JxD2Ftf8LsGcwSINkoIaY272624	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	intact-crc:768EC09A4CC376AE|rigid:4AOfcuQ06NmTWIifJKHTT/wuLwA	false	glutathione s tranferase tag:n-n	mutation:80-80|binding-associated region:18-182|mutation decreasing interaction:92-92	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5ZRP9	uniprotkb:P51148	intact:EBI-26364295	intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689.5|ensembl:ENSP00000377440.3|intact:EBI-21355794	psi-mi:q5zrp9_legph(display_long)|uniprotkb:vipD(gene name)|psi-mi:vipD(display_short)|uniprotkb:lpg2831(locus name)	psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Lucas et al. (2014)	pubmed:25114243|imex:IM-28402	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26364674|imex:IM-28402-15	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_096826.1|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|rcsb pdb:4AKF|rcsb pdb:4KYI|interpro:IPR054392|mint:Q5ZRP9|refseq:WP_010948518.1|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|interpro:IPR052580"	"refseq:NP_004574.2|refseq:NP_958842.1|refseq:NP_001238968.1|ensembl:ENSG00000108774.15(gene)|ensembl:ENST00000346213.9(transcript)|ensembl:ENST00000393860.7(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0012505""(endomembrane system)|go:""GO:0019003""(GDP binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042470""(melanosome)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51148|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9820960|refseq:XP_011523392.1|refseq:XP_011523393.1|panther:PTHR24073(orthology-group)"	"go:""GO:0005768""(endosome)"	-	-	figure legend:f5|caution:The figure shows Rab5a-Q79L, not Rab5c-Q80L, but the text refers to Rab5c-Q80L. We believe it is probably a typo error and curated the interaction with Rab5c.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2020/10/05	2024/11/14	rogid:+GMms/JxD2Ftf8LsGcwSINkoIaY272624	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	intact-crc:F12FDDB2BD76DCF8|rigid:4AOfcuQ06NmTWIifJKHTT/wuLwA	false	mutation disrupting interaction:442-442|mcherry fluorescent protein tag:n-n|mutation with no effect:476-476|mutation with no effect:461-461	green fluorescent protein tag:n-n|mutation:80-80|binding-associated region:18-182	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q5ZRP9	uniprotkb:P51148	intact:EBI-26364295	intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689.5|ensembl:ENSP00000377440.3|intact:EBI-21355794	psi-mi:q5zrp9_legph(display_long)|uniprotkb:vipD(gene name)|psi-mi:vipD(display_short)|uniprotkb:lpg2831(locus name)	psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym)	"psi-mi:""MI:0071""(molecular sieving)"	Lucas et al. (2014)	pubmed:25114243|imex:IM-28402	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26364713|imex:IM-28402-17	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_096826.1|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|rcsb pdb:4AKF|rcsb pdb:4KYI|interpro:IPR054392|mint:Q5ZRP9|refseq:WP_010948518.1|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|interpro:IPR052580"	"refseq:NP_004574.2|refseq:NP_958842.1|refseq:NP_001238968.1|ensembl:ENSG00000108774.15(gene)|ensembl:ENST00000346213.9(transcript)|ensembl:ENST00000393860.7(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0012505""(endomembrane system)|go:""GO:0019003""(GDP binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042470""(melanosome)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51148|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9820960|refseq:XP_011523392.1|refseq:XP_011523393.1|panther:PTHR24073(orthology-group)"	-	-	-	"figure legend:sf3|comment:""\""Small angle X-ray scattering (SAXS) and gel filtration chromatography analysis suggest a heterodimeric VipD1–621–Rab5c18–182(Q80L) complex in solution, indicating that N18 was not involved in any oligomer formation (Fig. 6 A and B and Fig. S3).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/05	2024/11/14	rogid:+GMms/JxD2Ftf8LsGcwSINkoIaY272624	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	intact-crc:8FDF55007F6168DF|rigid:4AOfcuQ06NmTWIifJKHTT/wuLwA	false	binding-associated region:1-621	mutation:80-80|binding-associated region:18-182	2	2	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5ZRP9	uniprotkb:P51148	intact:EBI-26364295	intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689.5|ensembl:ENSP00000377440.3|intact:EBI-21355794	psi-mi:q5zrp9_legph(display_long)|uniprotkb:vipD(gene name)|psi-mi:vipD(display_short)|uniprotkb:lpg2831(locus name)	psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym)	"psi-mi:""MI:0826""(x ray scattering)"	Lucas et al. (2014)	pubmed:25114243|imex:IM-28402	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26364761|imex:IM-28402-23	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_096826.1|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|rcsb pdb:4AKF|rcsb pdb:4KYI|interpro:IPR054392|mint:Q5ZRP9|refseq:WP_010948518.1|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|interpro:IPR052580"	"refseq:NP_004574.2|refseq:NP_958842.1|refseq:NP_001238968.1|ensembl:ENSG00000108774.15(gene)|ensembl:ENST00000346213.9(transcript)|ensembl:ENST00000393860.7(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0012505""(endomembrane system)|go:""GO:0019003""(GDP binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042470""(melanosome)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51148|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9820960|refseq:XP_011523392.1|refseq:XP_011523393.1|panther:PTHR24073(orthology-group)"	-	-	-	"figure legend:f6|comment:""\""Small angle X-ray scattering (SAXS) and gel filtration chromatography analysis suggest a heterodimeric VipD1–621–Rab5c18–182(Q80L) complex in solution, indicating that N18 was not involved in any oligomer formation (Fig. 6 A and B and Fig. S3).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/05	2024/11/14	rogid:+GMms/JxD2Ftf8LsGcwSINkoIaY272624	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	intact-crc:440C75D45C84DED7|rigid:4AOfcuQ06NmTWIifJKHTT/wuLwA	false	binding-associated region:19-564	mutation:80-80|binding-associated region:18-182	2	2	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15418	uniprotkb:A1JU68	intact:EBI-963034|uniprotkb:A6NGG4|intact:EBI-1383804|uniprotkb:A8K9K7|uniprotkb:B7Z5J0|uniprotkb:Q5SVM5|uniprotkb:Q5SVM8|uniprotkb:Q5SVM9|uniprotkb:Q96C05|uniprotkb:Q9BQK2|uniprotkb:B2RDY8|uniprotkb:E9PRI4|ensembl:ENSP00000363283.2|ensembl:ENSP00000486881.1	intact:EBI-26365850	psi-mi:ks6a1_human(display_long)|uniprotkb:RPS6KA1(gene name)|psi-mi:RPS6KA1(display_short)|uniprotkb:RSK1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:MAPKAPK1A(gene name synonym)|uniprotkb:Ribosomal S6 kinase 1(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1a(gene name synonym)	psi-mi:a1ju68_yere8(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:YEP0010(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Höfling et al. (2013)	imex:IM-28412|pubmed:25513777	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:393305(yere8)|taxid:393305(""Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26365713|imex:IM-28412-1	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001006666.1|refseq:NP_002944.2|refseq:NP_001317370.1|dip:DIP-29987N|ensembl:ENSG00000117676.14(gene)|ensembl:ENSG00000281877.3(gene)|ensembl:ENST00000374168.7(transcript)|ensembl:ENST00000629832.3(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004712""(protein serine/threonine/tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043555""(regulation of translation in response to stress)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045202""(synapse)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0072574""(hepatocyte proliferation)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000491""(positive regulation of hepatic stellate cell activation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041906|mint:Q15418|rcsb pdb:2WNT|rcsb pdb:2Z7Q|rcsb pdb:2Z7R|rcsb pdb:2Z7S|rcsb pdb:3RNY|rcsb pdb:3TEI|rcsb pdb:4H3P|rcsb pdb:4NIF|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:6TWY|rcsb pdb:7P74|rcsb pdb:7PC8|rcsb pdb:7QQL|rcsb pdb:8WF4|rcsb pdb:8XOV|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907|reactome:R-HSA-9856649|panther:PTHR24351(orthology-group)"	"go:""GO:0005576""(extracellular region)|mint:A1JU68|interpro:IPR001611(Leucine-rich repeat)|refseq:WP_011117630.1|refseq:YP_001004064.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR051071"	-	-	-	figure legend:f2a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/10/06	2025/02/03	rogid:kx+9PwIH4KR0iTxpv6epDKNqHBE9606	rogid:VVqEgBCKVWBYcComxe+/RinGpF0393305	intact-crc:D375B3A8D7595380|rigid:Oh+3vI7s3cvW4YWOHf84o83wmmQ	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q16513	uniprotkb:A1JU68	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552.3	intact:EBI-26365850	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:a1ju68_yere8(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:YEP0010(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Höfling et al. (2013)	imex:IM-28412|pubmed:25513777	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:393305(yere8)|taxid:393305(""Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26365815|imex:IM-28412-3	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243.20(gene)|ensembl:ENST00000370521.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004698""(calcium,diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004699""(diacylglycerol-dependent, calcium-independent serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0010631""(epithelial cell migration)|go:""GO:0016301""(kinase activity)|go:""GO:0016604""(nuclear body)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030496""(midbody)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045296""(cadherin binding)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051301""(cell division)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|reactome:R-HSA-9856530|panther:PTHR24356(orthology-group)"	"go:""GO:0005576""(extracellular region)|mint:A1JU68|interpro:IPR001611(Leucine-rich repeat)|refseq:WP_011117630.1|refseq:YP_001004064.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR051071"	-	-	-	figure legend:f2a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/10/06	2025/02/03	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	rogid:VVqEgBCKVWBYcComxe+/RinGpF0393305	intact-crc:0D345E91C6BAAAD2|rigid:Oh+3vI7s3cvW4YWOHf84o83wmmQ	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A1JU68	uniprotkb:Q16513	intact:EBI-26365850	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552.3	psi-mi:a1ju68_yere8(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:YEP0010(locus name)	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Höfling et al. (2013)	imex:IM-28412|pubmed:25513777	"taxid:393305(yere8)|taxid:393305(""Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26365820|imex:IM-28412-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|mint:A1JU68|interpro:IPR001611(Leucine-rich repeat)|refseq:WP_011117630.1|refseq:YP_001004064.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR051071"	"refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243.20(gene)|ensembl:ENST00000370521.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004698""(calcium,diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004699""(diacylglycerol-dependent, calcium-independent serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0010631""(epithelial cell migration)|go:""GO:0016301""(kinase activity)|go:""GO:0016604""(nuclear body)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030496""(midbody)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045296""(cadherin binding)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051301""(cell division)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|reactome:R-HSA-9856530|panther:PTHR24356(orthology-group)"	-	-	-	figure legend:f2a f3d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/10/06	2025/02/03	rogid:VVqEgBCKVWBYcComxe+/RinGpF0393305	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	intact-crc:824D94E4E30179C0|rigid:Oh+3vI7s3cvW4YWOHf84o83wmmQ	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A1JU68	uniprotkb:Q15418	intact:EBI-26365850	intact:EBI-963034|uniprotkb:A6NGG4|intact:EBI-1383804|uniprotkb:A8K9K7|uniprotkb:B7Z5J0|uniprotkb:Q5SVM5|uniprotkb:Q5SVM8|uniprotkb:Q5SVM9|uniprotkb:Q96C05|uniprotkb:Q9BQK2|uniprotkb:B2RDY8|uniprotkb:E9PRI4|ensembl:ENSP00000363283.2|ensembl:ENSP00000486881.1	psi-mi:a1ju68_yere8(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:YEP0010(locus name)	psi-mi:ks6a1_human(display_long)|uniprotkb:RPS6KA1(gene name)|psi-mi:RPS6KA1(display_short)|uniprotkb:RSK1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:MAPKAPK1A(gene name synonym)|uniprotkb:Ribosomal S6 kinase 1(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1a(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Höfling et al. (2013)	imex:IM-28412|pubmed:25513777	"taxid:393305(yere8)|taxid:393305(""Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26365820|imex:IM-28412-5	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|mint:A1JU68|interpro:IPR001611(Leucine-rich repeat)|refseq:WP_011117630.1|refseq:YP_001004064.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR051071"	"refseq:NP_001006666.1|refseq:NP_002944.2|refseq:NP_001317370.1|dip:DIP-29987N|ensembl:ENSG00000117676.14(gene)|ensembl:ENSG00000281877.3(gene)|ensembl:ENST00000374168.7(transcript)|ensembl:ENST00000629832.3(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004712""(protein serine/threonine/tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043555""(regulation of translation in response to stress)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045202""(synapse)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0072574""(hepatocyte proliferation)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000491""(positive regulation of hepatic stellate cell activation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041906|mint:Q15418|rcsb pdb:2WNT|rcsb pdb:2Z7Q|rcsb pdb:2Z7R|rcsb pdb:2Z7S|rcsb pdb:3RNY|rcsb pdb:3TEI|rcsb pdb:4H3P|rcsb pdb:4NIF|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:6TWY|rcsb pdb:7P74|rcsb pdb:7PC8|rcsb pdb:7QQL|rcsb pdb:8WF4|rcsb pdb:8XOV|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907|reactome:R-HSA-9856649|panther:PTHR24351(orthology-group)"	-	-	-	figure legend:f2a f3d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/10/06	2025/02/03	rogid:VVqEgBCKVWBYcComxe+/RinGpF0393305	rogid:kx+9PwIH4KR0iTxpv6epDKNqHBE9606	intact-crc:824D94E4E30179C0|rigid:Oh+3vI7s3cvW4YWOHf84o83wmmQ	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q16512	uniprotkb:A1JU68	intact:EBI-602382|intact:EBI-1384186|intact:EBI-748186|uniprotkb:A8K7W5|uniprotkb:B2R9R4|uniprotkb:B3KVN3|uniprotkb:Q504U4|uniprotkb:Q8IUV5|uniprotkb:Q9UD44|uniprotkb:Q15143|ensembl:ENSP00000242783.7	intact:EBI-26365850	psi-mi:pkn1_human(display_long)|uniprotkb:PKN1(gene name)|psi-mi:PKN1(display_short)|uniprotkb:PKN(gene name synonym)|uniprotkb:PRK1(gene name synonym)|uniprotkb:PRKCL1(gene name synonym)|uniprotkb:PAK1(gene name synonym)|uniprotkb:Protease-activated kinase 1(gene name synonym)|uniprotkb:Protein kinase C-like 1(gene name synonym)|uniprotkb:Protein kinase C-like PKN(gene name synonym)|uniprotkb:Protein kinase PKN-alpha(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 1(gene name synonym)|uniprotkb:Serine-threonine protein kinase N(gene name synonym)	psi-mi:a1ju68_yere8(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:YEP0010(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Höfling et al. (2013)	imex:IM-28412|pubmed:25513777	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:393305(yere8)|taxid:393305(""Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26365825|imex:IM-28412-7	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002732.3|refseq:NP_998725.1|dip:DIP-34240N|ensembl:ENSG00000123143.13(gene)|ensembl:ENST00000242783.11(transcript)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001783""(B cell apoptotic process)|go:""GO:0002634""(regulation of germinal center formation)|go:""GO:0002637""(regulation of immunoglobulin production)|go:""GO:0003014""(renal system process)|go:""GO:0003682""(chromatin binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004697""(diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004698""(calcium,diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004699""(diacylglycerol-dependent, calcium-independent serine/threonine kinase activity)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006972""(hyperosmotic response)|go:""GO:0007165""(signal transduction)|go:""GO:0010631""(epithelial cell migration)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030496""(midbody)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042393""(histone binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0048536""(spleen development)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0060765""(regulation of androgen receptor signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037317|interpro:IPR037784|mint:Q16512|rcsb pdb:1CXZ|rcsb pdb:1URF|rcsb pdb:2RMK|rcsb pdb:4NKG|rcsb pdb:4OTD|rcsb pdb:4OTG|rcsb pdb:4OTH|rcsb pdb:4OTI|reactome:R-HSA-5625740|reactome:R-HSA-5625886|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|panther:PTHR24356(orthology-group)"	"go:""GO:0005576""(extracellular region)|mint:A1JU68|interpro:IPR001611(Leucine-rich repeat)|refseq:WP_011117630.1|refseq:YP_001004064.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR051071"	-	-	-	figure legend:f2c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/10/06	2025/02/28	rogid:4g0klnFDUlztO05MH9R4sECDTtU9606	rogid:VVqEgBCKVWBYcComxe+/RinGpF0393305	intact-crc:020B2B98B4194638|rigid:QpHW47RIfr0fZbN/fiJwf4MXDys	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P51812	uniprotkb:A1JU68	intact:EBI-1046616|uniprotkb:Q4VAP3|uniprotkb:Q59H26|uniprotkb:Q5JPK8|uniprotkb:Q7Z3Z7|ensembl:ENSP00000368884.3|uniprotkb:B2R9V4	intact:EBI-26365850	psi-mi:ks6a3_human(display_long)|uniprotkb:Insulin-stimulated protein kinase 1(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1b(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 3(gene name synonym)|uniprotkb:MAPKAPK1B(gene name synonym)|uniprotkb:Ribosomal S6 kinase 2(gene name synonym)|uniprotkb:pp90RSK2(gene name synonym)|uniprotkb:RPS6KA3(gene name)|psi-mi:RPS6KA3(display_short)|uniprotkb:ISPK1(gene name synonym)|uniprotkb:RSK2(gene name synonym)	psi-mi:a1ju68_yere8(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:YEP0010(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Höfling et al. (2013)	imex:IM-28412|pubmed:25513777	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:393305(yere8)|taxid:393305(""Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26365830|imex:IM-28412-9	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000177189.14(gene)|ensembl:ENST00000379565.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001501""(skeletal system development)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007417""(central nervous system development)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043555""(regulation of translation in response to stress)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045202""(synapse)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041905|interpro:IPR041906|mint:P51812|rcsb pdb:4D9T|rcsb pdb:4D9U|rcsb pdb:4JG6|rcsb pdb:4JG7|rcsb pdb:4JG8|rcsb pdb:4NUS|rcsb pdb:4NW5|rcsb pdb:4NW6|rcsb pdb:5D9K|rcsb pdb:5D9L|rcsb pdb:7OPO|rcsb pdb:8EQ5|rcsb pdb:8XEY|rcsb pdb:8XFY|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907|refseq:NP_004577.1|dip:DIP-38247N|efo:""Orphanet:192""|efo:""Orphanet:276630""|efo:""Orphanet:777""|panther:PTHR24351(orthology-group)"	"go:""GO:0005576""(extracellular region)|mint:A1JU68|interpro:IPR001611(Leucine-rich repeat)|refseq:WP_011117630.1|refseq:YP_001004064.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR051071"	-	-	-	figure legend:f2c f3d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/10/06	2025/02/28	rogid:zkX8NPvSEjVEap7TxboH2SKy9zg9606	rogid:VVqEgBCKVWBYcComxe+/RinGpF0393305	intact-crc:B2A09CEB274E6B84|rigid:3mp9LTUDzfT9F+sCrBpryBq6foU	false	-	necessary binding region:334-367	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q15418	uniprotkb:A1JU68	intact:EBI-963034|uniprotkb:A6NGG4|intact:EBI-1383804|uniprotkb:A8K9K7|uniprotkb:B7Z5J0|uniprotkb:Q5SVM5|uniprotkb:Q5SVM8|uniprotkb:Q5SVM9|uniprotkb:Q96C05|uniprotkb:Q9BQK2|uniprotkb:B2RDY8|uniprotkb:E9PRI4|ensembl:ENSP00000363283.2|ensembl:ENSP00000486881.1	intact:EBI-26365850	psi-mi:ks6a1_human(display_long)|uniprotkb:RPS6KA1(gene name)|psi-mi:RPS6KA1(display_short)|uniprotkb:RSK1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:MAPKAPK1A(gene name synonym)|uniprotkb:Ribosomal S6 kinase 1(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1a(gene name synonym)	psi-mi:a1ju68_yere8(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:YEP0010(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Höfling et al. (2013)	imex:IM-28412|pubmed:25513777	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:393305(yere8)|taxid:393305(""Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26365836|imex:IM-28412-11	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001006666.1|refseq:NP_002944.2|refseq:NP_001317370.1|dip:DIP-29987N|ensembl:ENSG00000117676.14(gene)|ensembl:ENSG00000281877.3(gene)|ensembl:ENST00000374168.7(transcript)|ensembl:ENST00000629832.3(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004712""(protein serine/threonine/tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043555""(regulation of translation in response to stress)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045202""(synapse)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0072574""(hepatocyte proliferation)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000491""(positive regulation of hepatic stellate cell activation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041906|mint:Q15418|rcsb pdb:2WNT|rcsb pdb:2Z7Q|rcsb pdb:2Z7R|rcsb pdb:2Z7S|rcsb pdb:3RNY|rcsb pdb:3TEI|rcsb pdb:4H3P|rcsb pdb:4NIF|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:6TWY|rcsb pdb:7P74|rcsb pdb:7PC8|rcsb pdb:7QQL|rcsb pdb:8WF4|rcsb pdb:8XOV|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907|reactome:R-HSA-9856649|panther:PTHR24351(orthology-group)"	"go:""GO:0005576""(extracellular region)|mint:A1JU68|interpro:IPR001611(Leucine-rich repeat)|refseq:WP_011117630.1|refseq:YP_001004064.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR051071"	-	-	-	"figure legend:f3d f4a f4b|comment:""\""Incubation with the full-length rYopM led to significantly enhanced phosphorylation of RSK at S380 compared with the medium and mock controls as well as to the incubation with the interaction-deficient truncated rYopM∆C protein (Fig. 4B and C).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/10/06	2025/02/03	rogid:kx+9PwIH4KR0iTxpv6epDKNqHBE9606	rogid:VVqEgBCKVWBYcComxe+/RinGpF0393305	intact-crc:0FD88789BE9D66F5|rigid:ESdpSw/IYfgHMW649oR/XwCRC9o	false	phosphorylated residue:380-380	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q16512	uniprotkb:A1JU68	intact:EBI-602382|intact:EBI-1384186|intact:EBI-748186|uniprotkb:A8K7W5|uniprotkb:B2R9R4|uniprotkb:B3KVN3|uniprotkb:Q504U4|uniprotkb:Q8IUV5|uniprotkb:Q9UD44|uniprotkb:Q15143|ensembl:ENSP00000242783.7	intact:EBI-26365850	psi-mi:pkn1_human(display_long)|uniprotkb:PKN1(gene name)|psi-mi:PKN1(display_short)|uniprotkb:PKN(gene name synonym)|uniprotkb:PRK1(gene name synonym)|uniprotkb:PRKCL1(gene name synonym)|uniprotkb:PAK1(gene name synonym)|uniprotkb:Protease-activated kinase 1(gene name synonym)|uniprotkb:Protein kinase C-like 1(gene name synonym)|uniprotkb:Protein kinase C-like PKN(gene name synonym)|uniprotkb:Protein kinase PKN-alpha(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 1(gene name synonym)|uniprotkb:Serine-threonine protein kinase N(gene name synonym)	psi-mi:a1ju68_yere8(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:YEP0010(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Höfling et al. (2013)	imex:IM-28412|pubmed:25513777	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:393305(yere8)|taxid:393305(""Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26369419|imex:IM-28412-12	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002732.3|refseq:NP_998725.1|dip:DIP-34240N|ensembl:ENSG00000123143.13(gene)|ensembl:ENST00000242783.11(transcript)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001783""(B cell apoptotic process)|go:""GO:0002634""(regulation of germinal center formation)|go:""GO:0002637""(regulation of immunoglobulin production)|go:""GO:0003014""(renal system process)|go:""GO:0003682""(chromatin binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004697""(diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004698""(calcium,diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004699""(diacylglycerol-dependent, calcium-independent serine/threonine kinase activity)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006972""(hyperosmotic response)|go:""GO:0007165""(signal transduction)|go:""GO:0010631""(epithelial cell migration)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030496""(midbody)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042393""(histone binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0048536""(spleen development)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0060765""(regulation of androgen receptor signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037317|interpro:IPR037784|mint:Q16512|rcsb pdb:1CXZ|rcsb pdb:1URF|rcsb pdb:2RMK|rcsb pdb:4NKG|rcsb pdb:4OTD|rcsb pdb:4OTG|rcsb pdb:4OTH|rcsb pdb:4OTI|reactome:R-HSA-5625740|reactome:R-HSA-5625886|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|panther:PTHR24356(orthology-group)"	"go:""GO:0005576""(extracellular region)|mint:A1JU68|interpro:IPR001611(Leucine-rich repeat)|refseq:WP_011117630.1|refseq:YP_001004064.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR051071"	-	-	-	figure legend:f2c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-a_549)|taxid:9606(Homo sapiens A549 lung carcinoma cell)	-	2020/10/06	2025/02/28	rogid:4g0klnFDUlztO05MH9R4sECDTtU9606	rogid:VVqEgBCKVWBYcComxe+/RinGpF0393305	intact-crc:44B4BF39660E7D67|rigid:QpHW47RIfr0fZbN/fiJwf4MXDys	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P51812	uniprotkb:A1JU68	intact:EBI-1046616|uniprotkb:Q4VAP3|uniprotkb:Q59H26|uniprotkb:Q5JPK8|uniprotkb:Q7Z3Z7|ensembl:ENSP00000368884.3|uniprotkb:B2R9V4	intact:EBI-26365850	psi-mi:ks6a3_human(display_long)|uniprotkb:Insulin-stimulated protein kinase 1(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1b(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 3(gene name synonym)|uniprotkb:MAPKAPK1B(gene name synonym)|uniprotkb:Ribosomal S6 kinase 2(gene name synonym)|uniprotkb:pp90RSK2(gene name synonym)|uniprotkb:RPS6KA3(gene name)|psi-mi:RPS6KA3(display_short)|uniprotkb:ISPK1(gene name synonym)|uniprotkb:RSK2(gene name synonym)	psi-mi:a1ju68_yere8(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:YEP0010(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Höfling et al. (2013)	imex:IM-28412|pubmed:25513777	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:393305(yere8)|taxid:393305(""Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26369423|imex:IM-28412-14	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000177189.14(gene)|ensembl:ENST00000379565.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001501""(skeletal system development)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007417""(central nervous system development)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043555""(regulation of translation in response to stress)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045202""(synapse)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041905|interpro:IPR041906|mint:P51812|rcsb pdb:4D9T|rcsb pdb:4D9U|rcsb pdb:4JG6|rcsb pdb:4JG7|rcsb pdb:4JG8|rcsb pdb:4NUS|rcsb pdb:4NW5|rcsb pdb:4NW6|rcsb pdb:5D9K|rcsb pdb:5D9L|rcsb pdb:7OPO|rcsb pdb:8EQ5|rcsb pdb:8XEY|rcsb pdb:8XFY|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907|refseq:NP_004577.1|dip:DIP-38247N|efo:""Orphanet:192""|efo:""Orphanet:276630""|efo:""Orphanet:777""|panther:PTHR24351(orthology-group)"	"go:""GO:0005576""(extracellular region)|mint:A1JU68|interpro:IPR001611(Leucine-rich repeat)|refseq:WP_011117630.1|refseq:YP_001004064.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR051071"	-	-	-	figure legend:f2c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-a_549)|taxid:9606(Homo sapiens A549 lung carcinoma cell)	-	2020/10/06	2025/02/28	rogid:zkX8NPvSEjVEap7TxboH2SKy9zg9606	rogid:VVqEgBCKVWBYcComxe+/RinGpF0393305	intact-crc:2905BF447B8C3C1F|rigid:3mp9LTUDzfT9F+sCrBpryBq6foU	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q9ZFS6	uniprotkb:P14780	intact:EBI-26361542	intact:EBI-1382326|uniprotkb:Q3LR70|uniprotkb:Q8N725|uniprotkb:Q9H4Z1|uniprotkb:B2R7V9|uniprotkb:Q9UCJ9|uniprotkb:Q9UCL1|uniprotkb:Q9UDK2|ensembl:ENSP00000361405.3	psi-mi:q9zfs6_staau(display_long)|uniprotkb:ERS329596_02062(orf name)|uniprotkb:SAMEA1531725_02062(orf name)|uniprotkb:set3(gene name)|psi-mi:set3(display_short)|uniprotkb:NCTC7878_00467(orf name)	psi-mi:mmp9_human(display_long)|uniprotkb:MMP9(gene name)|psi-mi:MMP9(display_short)|uniprotkb:CLG4B(gene name synonym)|uniprotkb:92 kDa type IV collagenase(gene name synonym)|uniprotkb:92 kDa gelatinase(gene name synonym)|uniprotkb:Gelatinase B(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Kurisaka et al. (2018)	imex:IM-28387|pubmed:29328525	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26361569|imex:IM-28387-1	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:1M4V|rcsb pdb:2R61|rcsb pdb:2Z8L|go:""GO:0005576""(extracellular region)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|refseq:WP_000784258.1|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)"	"ensembl:ENSG00000100985.7(gene)|ensembl:ENST00000372330.3(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006915""(apoptotic process)|go:""GO:0007566""(embryo implantation)|go:""GO:0008233""(peptidase activity)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016477""(cell migration)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030574""(collagen catabolic process)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045742""(positive regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071492""(cellular response to UV-A)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0150077""(regulation of neuroinflammatory response)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904645""(response to amyloid-beta)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000697""(negative regulation of epithelial cell differentiation involved in kidney development)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|go:""GO:2001258""(negative regulation of cation channel activity)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036375|interpro:IPR036943|mint:P14780|rcsb pdb:1GKC|rcsb pdb:1GKD|rcsb pdb:1ITV|rcsb pdb:1L6J|rcsb pdb:2OVX|rcsb pdb:2OVZ|rcsb pdb:2OW0|rcsb pdb:2OW1|rcsb pdb:2OW2|rcsb pdb:4H1Q|rcsb pdb:4H2E|rcsb pdb:4H3X|rcsb pdb:4H82|rcsb pdb:4HMA|rcsb pdb:4JIJ|rcsb pdb:4JQG|rcsb pdb:4WZV|rcsb pdb:4XCT|rcsb pdb:5CUH|rcsb pdb:5I12|rcsb pdb:5TH6|rcsb pdb:5TH9|rcsb pdb:5UE3|rcsb pdb:5UE4|rcsb pdb:6ESM|rcsb pdb:8K5V|rcsb pdb:8K5W|rcsb pdb:8K5X|rcsb pdb:8K5Y|reactome:R-HSA-1433557|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-2022090|reactome:R-HSA-3928665|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-9009391|refseq:NP_004985.2|dip:DIP-29518N|panther:PTHR10201(orthology-group)|efo:""Orphanet:1040"""	-	-	-	"figure legend:f2a f4b f5 f7b|comment:""\""he pull‐down assay using GST‐SSL5‐agarose in combination with zymography or western blotting showed that immobilized SSL5 bound to MMP‐9 derived from CHO‐K1 cells but did not bind to MMP‐9 from Lec2 mutant cells (Fig. 5).\""""|comment:""\""Pull‐down assay clearly showed that GST‐SSL5‐agarose failed to coprecipitate neuraminidase‐treated MMP‐9 (Fig. 4b).\""""|comment:""\""The pull‐down assay with GST‐SSL5‐agarose showed that MMP‐9 from benzyl‐GalNAc‐treated THP‐1 cells possessed weaker reactivity with GST‐SSL5 (Fig. 7b), suggesting that O‐gycans of MMP‐9 play a crucial role in its binding to GST‐SSL5.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/29	2024/11/14	rogid:4DgBnyO+rEHxGvitZFwkdvOV1xA1280	rogid:0PnzH1KPp4SKRWfRGotPA2eSHZk9606	intact-crc:AADCE29C407FF580|rigid:AcMf2qR/4dpoQy/nbUeG3xwGTOs	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q9ZFS6	uniprotkb:P14780	intact:EBI-26361542	intact:EBI-1382326|uniprotkb:Q3LR70|uniprotkb:Q8N725|uniprotkb:Q9H4Z1|uniprotkb:B2R7V9|uniprotkb:Q9UCJ9|uniprotkb:Q9UCL1|uniprotkb:Q9UDK2|ensembl:ENSP00000361405.3	psi-mi:q9zfs6_staau(display_long)|uniprotkb:ERS329596_02062(orf name)|uniprotkb:SAMEA1531725_02062(orf name)|uniprotkb:set3(gene name)|psi-mi:set3(display_short)|uniprotkb:NCTC7878_00467(orf name)	psi-mi:mmp9_human(display_long)|uniprotkb:MMP9(gene name)|psi-mi:MMP9(display_short)|uniprotkb:CLG4B(gene name synonym)|uniprotkb:92 kDa type IV collagenase(gene name synonym)|uniprotkb:92 kDa gelatinase(gene name synonym)|uniprotkb:Gelatinase B(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Kurisaka et al. (2018)	imex:IM-28387|pubmed:29328525	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26361608|imex:IM-28387-3	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:1M4V|rcsb pdb:2R61|rcsb pdb:2Z8L|go:""GO:0005576""(extracellular region)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|refseq:WP_000784258.1|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)"	"ensembl:ENSG00000100985.7(gene)|ensembl:ENST00000372330.3(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006915""(apoptotic process)|go:""GO:0007566""(embryo implantation)|go:""GO:0008233""(peptidase activity)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016477""(cell migration)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030574""(collagen catabolic process)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045742""(positive regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071492""(cellular response to UV-A)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0150077""(regulation of neuroinflammatory response)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904645""(response to amyloid-beta)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000697""(negative regulation of epithelial cell differentiation involved in kidney development)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|go:""GO:2001258""(negative regulation of cation channel activity)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036375|interpro:IPR036943|mint:P14780|rcsb pdb:1GKC|rcsb pdb:1GKD|rcsb pdb:1ITV|rcsb pdb:1L6J|rcsb pdb:2OVX|rcsb pdb:2OVZ|rcsb pdb:2OW0|rcsb pdb:2OW1|rcsb pdb:2OW2|rcsb pdb:4H1Q|rcsb pdb:4H2E|rcsb pdb:4H3X|rcsb pdb:4H82|rcsb pdb:4HMA|rcsb pdb:4JIJ|rcsb pdb:4JQG|rcsb pdb:4WZV|rcsb pdb:4XCT|rcsb pdb:5CUH|rcsb pdb:5I12|rcsb pdb:5TH6|rcsb pdb:5TH9|rcsb pdb:5UE3|rcsb pdb:5UE4|rcsb pdb:6ESM|rcsb pdb:8K5V|rcsb pdb:8K5W|rcsb pdb:8K5X|rcsb pdb:8K5Y|reactome:R-HSA-1433557|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-2022090|reactome:R-HSA-3928665|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-9009391|refseq:NP_004985.2|dip:DIP-29518N|panther:PTHR10201(orthology-group)|efo:""Orphanet:1040"""	-	-	-	"figure legend:f6b|comment:""\""The pull‐down assay showed that both the intact and de‐N‐glycosylated MMP‐9 were similarly coprecipitated with GST‐SSL5‐agarose (Fig. 6b).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/29	2024/11/14	rogid:4DgBnyO+rEHxGvitZFwkdvOV1xA1280	rogid:0PnzH1KPp4SKRWfRGotPA2eSHZk9606	intact-crc:C8545C7908A21C3E|rigid:AcMf2qR/4dpoQy/nbUeG3xwGTOs	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P04004	uniprotkb:M4QGE0	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	intact:EBI-26442833	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:m4qge0_morca(display_long)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442794|imex:IM-28479-1	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR045584|mint:M4QGE0|interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR005594(YadA-like, C-terminal)"	-	-	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:f7scb6lCKxK9ImbgVk2Oc5myxdg480	intact-crc:A345C387C8F553D7|rigid:TuiBWw78M3MUlag7axoVROPl3M8	false	necessary binding region:352-374	his tag:?-?|sufficient binding region:30-180	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P04004	uniprotkb:M4QTB3	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	intact:EBI-26442845	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:m4qtb3_morca(display_long)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442854|imex:IM-28479-3	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR045584|mint:M4QTB3|interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR005594(YadA-like, C-terminal)"	-	-	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:J3BY7fjr789wEx9cLQI0goOOV3I480	intact-crc:33EE10AA152E3F50|rigid:kePJD63DzvIpUVDoWkVSg+TC08Y	false	necessary binding region:352-374	his tag:?-?|binding-associated region:30-186	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P04004	uniprotkb:M4QK36	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	intact:EBI-26442860	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:m4qk36_morca(display_long)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442869|imex:IM-28479-21	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR045584|mint:M4QK36|interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR005594(YadA-like, C-terminal)"	-	-	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:YVHRyWo9hnlHdeDRX80sWCu6M0c480	intact-crc:309D5C1B367F7DEA|rigid:sge4rqKmt0kmrHa1F4c+j/wkpA0	false	necessary binding region:352-374	his tag:?-?|binding-associated region:30-200	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P04004	uniprotkb:O54407	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	intact:EBI-26442875	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:o54407_morca(display_long)|uniprotkb:uspA2(gene name)|psi-mi:uspA2(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442885|imex:IM-28479-5	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR045584|mint:O54407|interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR005594(YadA-like, C-terminal)"	-	-	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:NhevIjHKgWnjxidydA7tZn7S3M4480	intact-crc:9986CB01636E2E45|rigid:nDqL5q97l42ag2jhbCc2Af6NUcw	false	necessary binding region:352-374	his tag:?-?|binding-associated region:33-200	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:M4QTD3	uniprotkb:P04004	intact:EBI-26442891	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:m4qtd3_morca(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442900|imex:IM-28479-7	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR045584|mint:M4QTD3|interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR005594(YadA-like, C-terminal)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:l0UCsULv2iqxjJXz4h8riJo1aB8480	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:2F53891B288DF71F|rigid:ZOdGHRVuvp0tuwcWaIHD2cQd+e0	false	his tag:?-?|binding-associated region:30-206	necessary binding region:352-374	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:M4QG97	uniprotkb:P04004	intact:EBI-26442906	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:m4qg97_morca(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442913|imex:IM-28479-9	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR045584|mint:M4QG97|interpro:IPR005594(YadA-like, C-terminal)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:/AWUTtLi1XktFYh424FUcZlLBqw480	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:F0F2A9EF4FE92210|rigid:QBF532Q1h6RRo5FLv2v9K3UHUfI	false	his tag:?-?|sufficient binding region:30-180	necessary binding region:352-374	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q9XD55	uniprotkb:P04004	intact:EBI-26442919	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:q9xd55_morca(display_long)|uniprotkb:uspA2(gene name)|psi-mi:uspA2(display_short)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442930|imex:IM-28479-11	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR045584|mint:Q9XD55|interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR005594(YadA-like, C-terminal)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:iyS2PrO3SlpU93PB7IQs3jAWBHA480	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:BEC900457DEA9E3D|rigid:qWzIleqsxppHDVuTvz02DtVRfGw	false	his tag:?-?|binding-associated region:30-177	necessary binding region:352-374	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:M4QGE9	uniprotkb:P04004	intact:EBI-26442936	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:m4qge9_morca(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442944|imex:IM-28479-13	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR045584|mint:M4QGE9|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR005594(YadA-like, C-terminal)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:PGIMbTxzwVaHsDGftr/GEbpjkdo480	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:F848453D3937CBA7|rigid:EBbIZ02/jXDxa8FXrUu+BwQ2R/k	false	his tag:?-?|binding-associated region:30-177	necessary binding region:352-374	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:M4QK13	uniprotkb:P04004	intact:EBI-26442950	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:m4qk13_morca(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442959|imex:IM-28479-15	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|interpro:IPR045584|mint:M4QK13|interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR005594(YadA-like, C-terminal)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:VlNEGjixPKLmvGWhlL29j3X7EzE480	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:1182B2018A9F4CF0|rigid:W3eb2sy2sTipPxeWNxvKKpiPVHg	false	his tag:?-?|binding-associated region:30-165	necessary binding region:352-374	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:M4QIL3	uniprotkb:P04004	intact:EBI-26442965	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:m4qil3_morca(display_long)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442978|imex:IM-28479-17	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005594(YadA-like, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|interpro:IPR045584|mint:M4QIL3|interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR040630|interpro:IPR008635(Haemagluttinin motif)"	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	-	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:fITK71Xyh8VgCsrGbu2frYv0Kzs480	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:9C7000A8D3662A23|rigid:n4GuvfwPgUVLLn5M5n7v6LokUGo	false	his tag:?-?|binding-associated region:49-389	necessary binding region:352-374	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0421""(identification by antibody)"
intact:EBI-26443006	uniprotkb:P04004	-	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218.4	psi-mi:d5va98_morcb(display_short)|psi-mi:EBI-26443006(display_long)|uniprotkb:uspA2H(gene name)|psi-mi:uspA2H(display_short)|uniprotkb:MCR_0329(locus name)	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Su et al. (2013)	pubmed:23474333|imex:IM-28479	"taxid:1236608(""Moraxella catarrhalis (strain BBH18)"")|taxid:1236608(""Moraxella catarrhalis (strain BBH18)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26442997|imex:IM-28479-19	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:D5VA98(uniprot-removed-ac)	"refseq:NP_000629.3|ensembl:ENSG00000109072.14(gene)|ensembl:ENST00000226218.9(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048237""(rough endoplasmic reticulum lumen)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0051258""(protein polymerization)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061302""(smooth muscle cell-matrix adhesion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097421""(liver regeneration)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:1904090""(peptidase inhibitor complex)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|interpro:IPR051298|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|rcsb pdb:7RJ9|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N|panther:PTHR22917(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	"figure legend:FIG. 4|antagonist:""\""heparin CHEBI:28304\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/03	2025/03/10	rogid:hV2s41Y6PY5SNRTHjYrXAVMBoZA1236608	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	intact-crc:C86B801A3163014F|rigid:ZjnukMrLx9UPoxEJXDMkUW0+bmU	false	his tag:?-?|binding-associated region:50-498	necessary binding region:352-374	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0421""(identification by antibody)"
uniprotkb:Q824H6	uniprotkb:Q05397	intact:EBI-26494126	intact:EBI-702142|uniprotkb:Q14291|uniprotkb:Q9UD85|intact:EBI-11047590|uniprotkb:B4E2N6|uniprotkb:F5H4S4|ensembl:ENSP00000429474.1|ensembl:ENSP00000429911.1|uniprotkb:J3QT16|uniprotkb:Q8IYN9	psi-mi:q824h6_chlcv(display_long)|uniprotkb:CCA_00170(locus name)	psi-mi:fak1_human(display_long)|uniprotkb:PTK2(gene name)|psi-mi:PTK2(display_short)|uniprotkb:FAK(gene name synonym)|uniprotkb:FAK1(gene name synonym)|uniprotkb:pp125FAK(gene name synonym)|uniprotkb:Protein-tyrosine kinase 2(gene name synonym)|uniprotkb:Focal adhesion kinase-related nonkinase(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 71(gene name synonym)|uniprotkb:p125FAK(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Thwaites et al. (2014)	pubmed:25193659|imex:IM-28529	"taxid:227941(Chlamydia caviae)|taxid:227941(""Chlamydophila caviae (strain ATCC VR-813 / DSM 19441 / GPIC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26494109|imex:IM-28529-1	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_011006142.1|interpro:IPR011443(Protein of unknown function DUF1547)|mint:Q824H6|rcsb pdb:6FQ4	"refseq:NP_722560.1|refseq:NP_001186578.1|ensembl:ENSG00000169398.20(gene)|ensembl:ENST00000521059.5(transcript)|ensembl:ENST00000522684.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001725""(stress fiber)|go:""GO:0001890""(placenta development)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003779""(actin binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007172""(signal complex assembly)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0010632""(regulation of epithelial cell migration)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0016477""(cell migration)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035995""(detection of muscle stretch)|go:""GO:0036064""(ciliary basal body)|go:""GO:0038007""(netrin-activated signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0043197""(dendritic spine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048870""(cell motility)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060396""(growth hormone receptor signaling pathway)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900024""(regulation of substrate adhesion-dependent cell spreading)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR029071|interpro:IPR035963|interpro:IPR036137|interpro:IPR041390|interpro:IPR041784|interpro:IPR049385|mint:Q05397|rcsb pdb:1K04|rcsb pdb:1K05|rcsb pdb:1MP8|rcsb pdb:1OW6|rcsb pdb:1OW7|rcsb pdb:1OW8|rcsb pdb:2ETM|rcsb pdb:2IJM|rcsb pdb:3B71|rcsb pdb:3BZ3|rcsb pdb:3PXK|rcsb pdb:3S9O|rcsb pdb:4EBV|rcsb pdb:4EBW|rcsb pdb:4GU6|rcsb pdb:4GU9|rcsb pdb:4I4E|rcsb pdb:4I4F|rcsb pdb:4K8A|rcsb pdb:4K9Y|rcsb pdb:4KAB|rcsb pdb:4KAO|rcsb pdb:4NY0|rcsb pdb:4Q9S|rcsb pdb:6I8Z|rcsb pdb:6LES|rcsb pdb:6PW8|rcsb pdb:6YOJ|rcsb pdb:6YQ1|rcsb pdb:6YR9|rcsb pdb:6YT6|rcsb pdb:6YVS|rcsb pdb:6YVY|rcsb pdb:6YXV|rcsb pdb:7PI4|rcsb pdb:7W7Z|rcsb pdb:7W8B|rcsb pdb:7W8I|rcsb pdb:7W9U|reactome:R-HSA-111465|reactome:R-HSA-2029482|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-8874081|reactome:R-HSA-9009391|reactome:R-HSA-9634638|reactome:R-HSA-9664422|reactome:R-HSA-9860927|refseq:XP_016869162.1|panther:PTHR24418(orthology-group)"	"go:""GO:0001725""(stress fiber)|go:""GO:0005925""(focal adhesion)"	-	-	figure legend:fig.2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2020/11/12	2024/11/14	rogid:Z7bsNZEPluTO9rgq0EwdFcPhqaI227941	rogid:8q4JfaNYtMdXVLU77d1EtSP0lVg9606	intact-crc:967A8622F2184487|rigid:sop8jRUD89USLlwk4+hXfkWpgnQ	false	binding-associated region:640-740	O4'-phospho-L-tyrosine:397-397	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q824H6	uniprotkb:Q05397	intact:EBI-26494126	intact:EBI-702142|uniprotkb:Q14291|uniprotkb:Q9UD85|intact:EBI-11047590|uniprotkb:B4E2N6|uniprotkb:F5H4S4|ensembl:ENSP00000429474.1|ensembl:ENSP00000429911.1|uniprotkb:J3QT16|uniprotkb:Q8IYN9	psi-mi:q824h6_chlcv(display_long)|uniprotkb:CCA_00170(locus name)	psi-mi:fak1_human(display_long)|uniprotkb:PTK2(gene name)|psi-mi:PTK2(display_short)|uniprotkb:FAK(gene name synonym)|uniprotkb:FAK1(gene name synonym)|uniprotkb:pp125FAK(gene name synonym)|uniprotkb:Protein-tyrosine kinase 2(gene name synonym)|uniprotkb:Focal adhesion kinase-related nonkinase(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 71(gene name synonym)|uniprotkb:p125FAK(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Thwaites et al. (2014)	pubmed:25193659|imex:IM-28529	"taxid:227941(Chlamydia caviae)|taxid:227941(""Chlamydophila caviae (strain ATCC VR-813 / DSM 19441 / GPIC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26494268|imex:IM-28529-3	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_011006142.1|interpro:IPR011443(Protein of unknown function DUF1547)|mint:Q824H6|rcsb pdb:6FQ4	"refseq:NP_722560.1|refseq:NP_001186578.1|ensembl:ENSG00000169398.20(gene)|ensembl:ENST00000521059.5(transcript)|ensembl:ENST00000522684.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001725""(stress fiber)|go:""GO:0001890""(placenta development)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003779""(actin binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007172""(signal complex assembly)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0010632""(regulation of epithelial cell migration)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0016477""(cell migration)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035995""(detection of muscle stretch)|go:""GO:0036064""(ciliary basal body)|go:""GO:0038007""(netrin-activated signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0043197""(dendritic spine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048870""(cell motility)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060396""(growth hormone receptor signaling pathway)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900024""(regulation of substrate adhesion-dependent cell spreading)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR029071|interpro:IPR035963|interpro:IPR036137|interpro:IPR041390|interpro:IPR041784|interpro:IPR049385|mint:Q05397|rcsb pdb:1K04|rcsb pdb:1K05|rcsb pdb:1MP8|rcsb pdb:1OW6|rcsb pdb:1OW7|rcsb pdb:1OW8|rcsb pdb:2ETM|rcsb pdb:2IJM|rcsb pdb:3B71|rcsb pdb:3BZ3|rcsb pdb:3PXK|rcsb pdb:3S9O|rcsb pdb:4EBV|rcsb pdb:4EBW|rcsb pdb:4GU6|rcsb pdb:4GU9|rcsb pdb:4I4E|rcsb pdb:4I4F|rcsb pdb:4K8A|rcsb pdb:4K9Y|rcsb pdb:4KAB|rcsb pdb:4KAO|rcsb pdb:4NY0|rcsb pdb:4Q9S|rcsb pdb:6I8Z|rcsb pdb:6LES|rcsb pdb:6PW8|rcsb pdb:6YOJ|rcsb pdb:6YQ1|rcsb pdb:6YR9|rcsb pdb:6YT6|rcsb pdb:6YVS|rcsb pdb:6YVY|rcsb pdb:6YXV|rcsb pdb:7PI4|rcsb pdb:7W7Z|rcsb pdb:7W8B|rcsb pdb:7W8I|rcsb pdb:7W9U|reactome:R-HSA-111465|reactome:R-HSA-2029482|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-8874081|reactome:R-HSA-9009391|reactome:R-HSA-9634638|reactome:R-HSA-9664422|reactome:R-HSA-9860927|refseq:XP_016869162.1|panther:PTHR24418(orthology-group)"	-	-	-	figure legend:fig 5c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/12	2024/11/14	rogid:Z7bsNZEPluTO9rgq0EwdFcPhqaI227941	rogid:8q4JfaNYtMdXVLU77d1EtSP0lVg9606	intact-crc:D79B9F8589CCA0C1|rigid:sop8jRUD89USLlwk4+hXfkWpgnQ	false	biotin tag:n-n|binding-associated region:655-680|mutation disrupting interaction:660-660,663-664	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q05397	uniprotkb:Q824H6	intact:EBI-702142|uniprotkb:Q14291|uniprotkb:Q9UD85|intact:EBI-11047590|uniprotkb:B4E2N6|uniprotkb:F5H4S4|ensembl:ENSP00000429474.1|ensembl:ENSP00000429911.1|uniprotkb:J3QT16|uniprotkb:Q8IYN9	intact:EBI-26494126	psi-mi:fak1_human(display_long)|uniprotkb:PTK2(gene name)|psi-mi:PTK2(display_short)|uniprotkb:FAK(gene name synonym)|uniprotkb:FAK1(gene name synonym)|uniprotkb:pp125FAK(gene name synonym)|uniprotkb:Protein-tyrosine kinase 2(gene name synonym)|uniprotkb:Focal adhesion kinase-related nonkinase(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 71(gene name synonym)|uniprotkb:p125FAK(gene name synonym)	psi-mi:q824h6_chlcv(display_long)|uniprotkb:CCA_00170(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Thwaites et al. (2014)	pubmed:25193659|imex:IM-28529	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227941(Chlamydia caviae)|taxid:227941(""Chlamydophila caviae (strain ATCC VR-813 / DSM 19441 / GPIC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26498300|imex:IM-28529-4	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_722560.1|refseq:NP_001186578.1|ensembl:ENSG00000169398.20(gene)|ensembl:ENST00000521059.5(transcript)|ensembl:ENST00000522684.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001725""(stress fiber)|go:""GO:0001890""(placenta development)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003779""(actin binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007172""(signal complex assembly)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0010632""(regulation of epithelial cell migration)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0016477""(cell migration)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035995""(detection of muscle stretch)|go:""GO:0036064""(ciliary basal body)|go:""GO:0038007""(netrin-activated signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0043197""(dendritic spine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048870""(cell motility)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060396""(growth hormone receptor signaling pathway)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900024""(regulation of substrate adhesion-dependent cell spreading)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR029071|interpro:IPR035963|interpro:IPR036137|interpro:IPR041390|interpro:IPR041784|interpro:IPR049385|mint:Q05397|rcsb pdb:1K04|rcsb pdb:1K05|rcsb pdb:1MP8|rcsb pdb:1OW6|rcsb pdb:1OW7|rcsb pdb:1OW8|rcsb pdb:2ETM|rcsb pdb:2IJM|rcsb pdb:3B71|rcsb pdb:3BZ3|rcsb pdb:3PXK|rcsb pdb:3S9O|rcsb pdb:4EBV|rcsb pdb:4EBW|rcsb pdb:4GU6|rcsb pdb:4GU9|rcsb pdb:4I4E|rcsb pdb:4I4F|rcsb pdb:4K8A|rcsb pdb:4K9Y|rcsb pdb:4KAB|rcsb pdb:4KAO|rcsb pdb:4NY0|rcsb pdb:4Q9S|rcsb pdb:6I8Z|rcsb pdb:6LES|rcsb pdb:6PW8|rcsb pdb:6YOJ|rcsb pdb:6YQ1|rcsb pdb:6YR9|rcsb pdb:6YT6|rcsb pdb:6YVS|rcsb pdb:6YVY|rcsb pdb:6YXV|rcsb pdb:7PI4|rcsb pdb:7W7Z|rcsb pdb:7W8B|rcsb pdb:7W8I|rcsb pdb:7W9U|reactome:R-HSA-111465|reactome:R-HSA-2029482|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-8874081|reactome:R-HSA-9009391|reactome:R-HSA-9634638|reactome:R-HSA-9664422|reactome:R-HSA-9860927|refseq:XP_016869162.1|panther:PTHR24418(orthology-group)"	refseq:WP_011006142.1|interpro:IPR011443(Protein of unknown function DUF1547)|mint:Q824H6|rcsb pdb:6FQ4	-	-	-	"figure legend:fig. 4f|comment:""\""TarP-LD interaction with FAT was evaluated and directly compared with paxillin LD2 and TarP-mutLD. A positive control Cya18-Zip/Cya25-Zip was included. By measuring β-gal production, it was clear that Cya18-TarP-LD/Cya25-FAT or Cya18-Pax-LD2/Cya25-FAT-co-expressing bacteria exhibited activity that differed significantly from the negative control strain (Fig. 4F; p < 0.01 ANOVA and Tukey-Kramer post hoc test). Importantly, the Leu-to-Ala substitution mutant did not interact with FAT.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	"taxid:316385(ecodh)|taxid:316385(""Escherichia coli (strain K12 / DH10B)"")"	-	2020/11/12	2024/11/14	rogid:8q4JfaNYtMdXVLU77d1EtSP0lVg9606	rogid:Z7bsNZEPluTO9rgq0EwdFcPhqaI227941	intact-crc:6C8BD4944CDBDD80|rigid:sop8jRUD89USLlwk4+hXfkWpgnQ	false	binding-associated region:904..904-1052..1052	binding-associated region:640-740|mutation disrupting interaction:660-660,663-664	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q932F7	uniprotkb:P08603	intact:EBI-26369465	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	psi-mi:sdre_staam(display_long)|uniprotkb:sdrE(gene name)|psi-mi:sdrE(display_short)|uniprotkb:SAV0563(locus name)	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Zhang et al. (2017)	pubmed:28258151|imex:IM-28434	"taxid:158878(staam)|taxid:158878(""Staphylococcus aureus (strain Mu50 / ATCC 700699)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26369488|imex:IM-28434-1	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR050972|rcsb pdb:5WTA|rcsb pdb:5WTB|mint:Q932F7|refseq:WP_000610237.1|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR019931|interpro:IPR033764|interpro:IPR041171|interpro:IPR005877(YSIRK Gram-positive signal peptide)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	pdbe:5wtb	-	-	figure legend:F3A F3D T1 SF2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/16	2025/01/22	rogid:7whrWG4mQYp7Cw6oDDq01h3nOdw158878	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	intact-crc:41691586B0343026|rigid:b9mvI93Z8/0tpq6x2HDfRA2OE5c	false	his tag:n-n|binding-associated region:270-599	binding-associated region:1206-1226	2	2	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q932F7	uniprotkb:P08603	intact:EBI-26369465	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	psi-mi:sdre_staam(display_long)|uniprotkb:sdrE(gene name)|psi-mi:sdrE(display_short)|uniprotkb:SAV0563(locus name)	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Zhang et al. (2017)	pubmed:28258151|imex:IM-28434	"taxid:158878(staam)|taxid:158878(""Staphylococcus aureus (strain Mu50 / ATCC 700699)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26369518|imex:IM-28434-5	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR050972|rcsb pdb:5WTA|rcsb pdb:5WTB|mint:Q932F7|refseq:WP_000610237.1|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR019931|interpro:IPR033764|interpro:IPR041171|interpro:IPR005877(YSIRK Gram-positive signal peptide)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	-	-	-	figure legend:F1E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.4x10^-6(molar)	2020/10/16	2025/01/22	rogid:7whrWG4mQYp7Cw6oDDq01h3nOdw158878	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	intact-crc:80BE3AF83EE953B9|rigid:b9mvI93Z8/0tpq6x2HDfRA2OE5c	false	binding-associated region:270-599|his tag:n-n	sufficient binding region:1206-1226|glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q932F7	uniprotkb:P08603	intact:EBI-26369465	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	psi-mi:sdre_staam(display_long)|uniprotkb:sdrE(gene name)|psi-mi:sdrE(display_short)|uniprotkb:SAV0563(locus name)	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Zhang et al. (2017)	pubmed:28258151|imex:IM-28434	"taxid:158878(staam)|taxid:158878(""Staphylococcus aureus (strain Mu50 / ATCC 700699)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26369498|imex:IM-28434-3	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR050972|rcsb pdb:5WTA|rcsb pdb:5WTB|mint:Q932F7|refseq:WP_000610237.1|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR019931|interpro:IPR033764|interpro:IPR041171|interpro:IPR005877(YSIRK Gram-positive signal peptide)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	-	-	-	figure legend:F1B F1C F1D F3B F3C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/16	2025/01/22	rogid:7whrWG4mQYp7Cw6oDDq01h3nOdw158878	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	intact-crc:2114251910E54274|rigid:b9mvI93Z8/0tpq6x2HDfRA2OE5c	false	mutation decreasing interaction:334-334|mutation decreasing interaction:335-335|mutation decreasing interaction:419-419|mutation disrupting interaction:588-588|binding-associated region:270-599	mutation disrupting interaction:1208-1208|mutation increasing interaction:1210-1210|mutation decreasing interaction:1211-1211|mutation increasing interaction:1212-1212|mutation increasing interaction:1213-1213|mutation increasing interaction:1214-1214|mutation with no effect:1215-1215|mutation increasing interaction:1216-1216|mutation with no effect:1217-1217|mutation disrupting interaction:1206-1206|mutation decreasing interaction:1207-1207|mutation increasing interaction:1218-1218|mutation with no effect:1219-1219|mutation with no effect:1220-1220|mutation with no effect:1222-1222|mutation increasing interaction:1223-1223|mutation increasing interaction:1224-1224|mutation increasing interaction:1225-1225|mutation decreasing interaction:1226-1226|mutation decreasing interaction:1209-1209|sufficient binding region:1206-1226|glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q932F7	uniprotkb:P08603	intact:EBI-26369465	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	psi-mi:sdre_staam(display_long)|uniprotkb:sdrE(gene name)|psi-mi:sdrE(display_short)|uniprotkb:SAV0563(locus name)	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	"psi-mi:""MI:0071""(molecular sieving)"	Zhang et al. (2017)	pubmed:28258151|imex:IM-28434	"taxid:158878(staam)|taxid:158878(""Staphylococcus aureus (strain Mu50 / ATCC 700699)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26369649|imex:IM-28434-7	intact-miscore:0.65	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR050972|rcsb pdb:5WTA|rcsb pdb:5WTB|mint:Q932F7|refseq:WP_000610237.1|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR019931|interpro:IPR033764|interpro:IPR041171|interpro:IPR005877(YSIRK Gram-positive signal peptide)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	-	-	-	figure legend:SF2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/16	2025/01/22	rogid:7whrWG4mQYp7Cw6oDDq01h3nOdw158878	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	intact-crc:C4946DE8A1836212|rigid:b9mvI93Z8/0tpq6x2HDfRA2OE5c	false	binding-associated region:270-599	binding-associated region:1206-1226	2	2	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0H3NF08	uniprotkb:O00161	intact:EBI-27055528	intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_003816.2|refseq:NP_570710.1|refseq:XP_016878183.1|ensembl:ENSG00000092531.10(gene)|ensembl:ENST00000249647.8(transcript)|go:""GO:0002553""(histamine secretion by mast cell)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006887""(exocytosis)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006903""(vesicle targeting)|go:""GO:0015031""(protein transport)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042581""(specific granule)|go:""GO:0042582""(azurophil granule)|go:""GO:0043005""(neuron projection)|go:""GO:0061025""(membrane fusion)|go:""GO:0070032""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0098793""(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR19305(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P50402	intact:EBI-27055528	intact:EBI-489887|ensembl:ENSP00000358857.4|ensembl:ENSP00000507533.1|uniprotkb:Q6FI02	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000102119.12(gene)|ensembl:ENST00000369842.9(transcript)|ensembl:ENST00000683627.1(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006936""(muscle contraction)|go:""GO:0007517""(muscle organ development)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071763""(nuclear membrane organization)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0160045""(TMEM240-body)|go:""GO:1990000""(amyloid fibril formation)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|refseq:NP_000108.1|efo:""Orphanet:98863""|dip:DIP-34638N|panther:PTHR15171(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8N766	intact:EBI-27055528	intact:EBI-1044442|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62|ensembl:ENSP00000420608.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:480898""|ensembl:ENSG00000127463.16(gene)|ensembl:ENST00000477853.6(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072546""(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|rcsb pdb:8EOI|rcsb pdb:8J0N|rcsb pdb:8J0O|rcsb pdb:8S9S|rcsb pdb:9C7V|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|refseq:NP_055862.1|panther:PTHR21573(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P08195	intact:EBI-27055528	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q96AC1	intact:EBI-27055528	intact:EBI-4399465|uniprotkb:Q14840|uniprotkb:Q86TY7|uniprotkb:B5TJY2|ensembl:ENSP00000340391.3|ensembl:ENSP00000378993.2|intact:EBI-21355423	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ferm2_human(display_long)|uniprotkb:FERMT2(gene name)|psi-mi:FERMT2(display_short)|uniprotkb:KIND2(gene name synonym)|uniprotkb:MIG2(gene name synonym)|uniprotkb:PLEKHC1(gene name synonym)|uniprotkb:Kindlin-2(gene name synonym)|uniprotkb:Mitogen-inducible gene 2 protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001128471.1|refseq:NP_001128472.1|refseq:NP_006823.1|ensembl:ENSG00000073712.15(gene)|ensembl:ENST00000341590.8(transcript)|ensembl:ENST00000395631.6(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031674""(I band)|go:""GO:0033622""(integrin activation)|go:""GO:0033625""(positive regulation of integrin activation)|go:""GO:0034334""(adherens junction maintenance)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046332""(SMAD binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0051015""(actin filament binding)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060173""(limb development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902414""(protein localization to cell junction)|go:""GO:1902462""(positive regulation of mesenchymal stem cell proliferation)|go:""GO:1903691""(positive regulation of wound healing, spreading of epidermal cells)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR037837|interpro:IPR037843|interpro:IPR040790|mint:Q96AC1|rcsb pdb:2LGX|rcsb pdb:2LKO|rcsb pdb:2MSU|rcsb pdb:4F7H|rcsb pdb:6U4N|rcsb pdb:6XTJ|reactome:R-HSA-446353|reactome:R-HSA-9013149|reactome:R-HSA-9013423|panther:PTHR16160(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:nmlzKrHEw/aEw6C8i9+G/80jbuE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q7KZI7	intact:EBI-27055528	intact:EBI-516560|uniprotkb:Q15449|uniprotkb:Q15524|uniprotkb:Q5XGA3|uniprotkb:Q68A18|uniprotkb:Q96HB3|uniprotkb:Q96RG0|ensembl:ENSP00000385751.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mark2_human(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001034558.2|refseq:NP_001156768.1|refseq:NP_001156769.1|refseq:NP_004945.4|refseq:NP_059672.2|ensembl:ENSG00000072518.23(gene)|ensembl:ENST00000402010.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0001764""(neuron migration)|go:""GO:0003723""(RNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008289""(lipid binding)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0030425""(dendrite)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0050770""(regulation of axonogenesis)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051646""(mitochondrion localization)|go:""GO:0061564""(axon development)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071963""(establishment or maintenance of cell polarity regulating cell shape)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097427""(microtubule bundle)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1904526""(regulation of microtubule binding)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:Q7KZI7|rcsb pdb:3IEC|rcsb pdb:5EAK|rcsb pdb:5KZ7|rcsb pdb:5KZ8|rcsb pdb:8TXY|dip:DIP-31321N|panther:PTHR24346(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:yfUqSCu4bgkncBd6hRRg5pKkArc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O60716	intact:EBI-27055528	intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	"psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:""p120(cas)""(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000198561.16(gene)|ensembl:ENST00000399050.10(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009986""(cell surface)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016342""(catenin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030426""(growth cone)|go:""GO:0030496""(midbody)|go:""GO:0043197""(dendritic spine)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045296""(cadherin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098831""(presynaptic active zone cytoplasmic component)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0150107""(positive regulation of protein localization to cell-cell junction)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9833576|refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|efo:""Orphanet:1997""|dip:DIP-33850N|panther:PTHR10372(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:HgMvbcDKedE291TIvIOqLFT3srw9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q15758	intact:EBI-27055528	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|ensembl:ENSG00000105281.13(gene)|ensembl:ENST00000542575.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0006868""(glutamine transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010585""(glutamine secretion)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015183""(L-aspartate transmembrane transporter activity)|go:""GO:0015186""(L-glutamine transmembrane transporter activity)|go:""GO:0015194""(L-serine transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0016020""(membrane)|go:""GO:0022834""(ligand-gated channel activity)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070207""(protein homotrimerization)|go:""GO:0140009""(L-aspartate import across plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1903803""(L-glutamine import across plasma membrane)|interpro:IPR001991(""Sodium:dicarboxylate symporter"")|interpro:IPR018107|interpro:IPR036458|interpro:IPR050746|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|rcsb pdb:7BCQ|rcsb pdb:7BCS|rcsb pdb:7BCT|rcsb pdb:8OUD|rcsb pdb:8OUH|rcsb pdb:8OUJ|rcsb pdb:8QRO|rcsb pdb:8QRP|rcsb pdb:8QRQ|rcsb pdb:8QRR|rcsb pdb:8QRS|rcsb pdb:8QRU|rcsb pdb:8QRV|rcsb pdb:8QRW|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|panther:PTHR11958(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q86YQ8	intact:EBI-27055528	intact:EBI-1642325|uniprotkb:Q2TB41|intact:EBI-2835651|uniprotkb:Q86VY2|ensembl:ENSP00000329748.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:cpne8_human(display_long)|uniprotkb:CPNE8(gene name)|psi-mi:CPNE8(display_short)|uniprotkb:Copine VIII(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_705898.1|refseq:XP_016874340.1|ensembl:ENSG00000139117.14(gene)|ensembl:ENST00000331366.10(transcript)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071277""(cellular response to calcium ion)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010734(Copine)|interpro:IPR035892|interpro:IPR036465|interpro:IPR037768|interpro:IPR045052|mint:Q86YQ8|reactome:R-HSA-9013148|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013409|panther:PTHR10857(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:xTDQ9oRlt7RUyxsTJiRfMjVdbkI9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q16625	intact:EBI-27055528	intact:EBI-2903088|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4|ensembl:ENSP00000347379.2|ensembl:ENSP00000379719.2|ensembl:ENSP00000505426.1|ensembl:ENSP00000505541.1|ensembl:ENSP00000506162.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000197822.12(gene)|ensembl:ENST00000355237.6(transcript)|ensembl:ENST00000396442.7(transcript)|ensembl:ENST00000680027.1(transcript)|ensembl:ENST00000681041.1(transcript)|ensembl:ENST00000681586.1(transcript)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010827""(regulation of D-glucose transmembrane transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070160""(tight junction)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:1902463""(protein localization to cell leading edge)|go:""GO:1905605""(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|mint:Q16625|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|refseq:XP_016864402.1|refseq:XP_016864403.1|dip:DIP-42791N|efo:""Orphanet:1229""|panther:PTHR23288(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P27448	intact:EBI-27055528	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9NSK0	intact:EBI-27055528	intact:EBI-949319|intact:EBI-28986540|uniprotkb:Q66K28|uniprotkb:B3KPI3|uniprotkb:B3KSQ3|uniprotkb:B3KNY4|uniprotkb:Q96EG6|uniprotkb:B4DME9|ensembl:ENSP00000340221.5|ensembl:ENSP00000377620.2|ensembl:ENSP00000418031.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:klc4_human(display_long)|uniprotkb:Kinesin-like protein 8(gene name synonym)|uniprotkb:KLC4(gene name)|psi-mi:KLC4(display_short)|uniprotkb:KNSL8(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_612352.1|refseq:NP_958929.1|refseq:NP_958930.1|refseq:NP_958931.1|refseq:NP_001275963.1|refseq:NP_001275964.1|ensembl:ENSG00000137171.15(gene)|ensembl:ENST00000347162.10(transcript)|ensembl:ENST00000394056.6(transcript)|ensembl:ENST00000479388.5(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0019894""(kinesin binding)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q9NSK0|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|panther:PTHR45783(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:8wcjm5q5W1xiMTe50m3hpL4jy609606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q12959	intact:EBI-27055528	intact:EBI-357481|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21|ensembl:ENSP00000391732.2|ensembl:ENSP00000407531.1|ensembl:ENSP00000499437.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:199306""|ensembl:ENSG00000075711.21(gene)|ensembl:ENST00000419354.5(transcript)|ensembl:ENST00000448528.6(transcript)|ensembl:ENST00000670935.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001658""(branching involved in ureteric bud morphogenesis)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0001772""(immunological synapse)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0002088""(lens development in camera-type eye)|go:""GO:0004385""(guanylate kinase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0005604""(basement membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007399""(nervous system development)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0014704""(intercalated disc)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030054""(cell junction)|go:""GO:0030432""(peristalsis)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031253""(cell projection membrane)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0031579""(membrane raft organization)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031641""(regulation of myelination)|go:""GO:0033268""(node of Ranvier)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042383""(sarcolemma)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042982""(amyloid precursor protein metabolic process)|go:""GO:0043005""(neuron projection)|go:""GO:0043113""(receptor clustering)|go:""GO:0043219""(lateral loop)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048608""(reproductive structure development)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0048745""(smooth muscle tissue development)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0051660""(establishment of centrosome localization)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060022""(hard palate development)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0097016""(L27 domain binding)|go:""GO:0097025""(MPP7-DLG1-LIN7 complex)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097120""(receptor localization to synapse)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0098915""(membrane repolarization during ventricular cardiac muscle cell action potential)|go:""GO:0098919""(structural constituent of postsynaptic density)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099645""(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:1902305""(regulation of sodium ion transmembrane transport)|go:""GO:1902473""(regulation of protein localization to synapse)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903286""(regulation of potassium ion import)|go:""GO:1903753""(negative regulation of p38MAPK cascade)|go:""GO:1903764""(regulation of potassium ion export across plasma membrane)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313(""Membrane-associated guanylate kinase (MAGUK) scaffold protein"")|interpro:IPR019583|interpro:IPR036034|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036892|interpro:IPR050614|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|rcsb pdb:7PC3|rcsb pdb:8CN1|rcsb pdb:8CN3|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_001277912.1|refseq:NP_004078.2|refseq:XP_005269346.1|refseq:XP_011510804.1|refseq:XP_011510805.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861299.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|panther:PTHR23119(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8WUY9	intact:EBI-27055528	intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|uniprotkb:B4DUT4|ensembl:ENSP00000265036.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499.13(gene)|ensembl:ENST00000265036.10(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0016477""(cell migration)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0035556""(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|mint:Q8WUY9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|panther:PTHR16206(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9P0L0	intact:EBI-27055528	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_003565.4|refseq:NP_919415.2|ensembl:ENSG00000101558.14(gene)|ensembl:ENST00000400000.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031982""(vesicle)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035627""(ceramide transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0061025""(membrane fusion)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0090114""(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|dip:DIP-41135N|panther:PTHR10809(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q5JTV8	intact:EBI-27055528	intact:EBI-2559665|ensembl:ENSP00000476687.1|uniprotkb:Q9H8Y6|uniprotkb:Q8IZ65|uniprotkb:Q5JTV6|uniprotkb:B0QZ57|uniprotkb:Q9Y3X5|uniprotkb:Q9HAJ1|uniprotkb:Q9NV52|uniprotkb:A8K630|intact:EBI-40264785|uniprotkb:A0A0A0MSK5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:toip1_human(display_long)|uniprotkb:TOR1AIP1(gene name)|psi-mi:TOR1AIP1(display_short)|uniprotkb:Lamin-associated protein 1B(gene name synonym)|uniprotkb:LAP1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000143337.19(gene)|ensembl:ENST00000606911.7(transcript)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0051117""(ATPase binding)|go:""GO:0071763""(nuclear membrane organization)|go:""GO:0090435""(protein localization to nuclear envelope)|interpro:IPR008662(Lamina-associated polypeptide 1C)|interpro:IPR038599|interpro:IPR046753|interpro:IPR046754|mint:Q5JTV8|rcsb pdb:4TVS|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_001254507.1|refseq:NP_056417.2|dip:DIP-56692N|efo:""Orphanet:424261""|panther:PTHR18843(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:qFH5HTm3fcIwmGL486H8IqZHG489606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O95721	intact:EBI-27055528	intact:EBI-490676|ensembl:ENSP00000215730.6	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:snp29_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-29(gene name synonym)|uniprotkb:Soluble 29 kDa NSF attachment protein(gene name synonym)|uniprotkb:SNAP29(gene name)|psi-mi:SNAP29(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000099940.12(gene)|ensembl:ENST00000215730.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005776""(autophagosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006903""(vesicle targeting)|go:""GO:0015031""(protein transport)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0016240""(autophagosome membrane docking)|go:""GO:0019905""(syntaxin binding)|go:""GO:0020018""(ciliary pocket membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0061025""(membrane fusion)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098793""(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|mint:O95721|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-6798695|reactome:R-HSA-6811438|refseq:NP_004773.1|efo:""Orphanet:66631""|dip:DIP-56475N|panther:PTHR19305(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:4HyjERPnEDdBgiGt70N9oyrMN1k9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P29317	intact:EBI-27055528	intact:EBI-702104|uniprotkb:Q8N3Z2|ensembl:ENSP00000351209.5|uniprotkb:B5A968|intact:EBI-28989000	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:epha2_human(display_long)|uniprotkb:Tyrosine-protein kinase receptor ECK(gene name synonym)|uniprotkb:Epithelial cell kinase(gene name synonym)|uniprotkb:EPHA2(gene name)|psi-mi:EPHA2(display_short)|uniprotkb:ECK(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000142627.13(gene)|ensembl:ENST00000358432.8(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0002043""(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008288""(boss receptor activity)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009986""(cell surface)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0014028""(notochord formation)|go:""GO:0016477""(cell migration)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019838""(growth factor binding)|go:""GO:0021915""(neural tube development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0043235""(receptor complex)|go:""GO:0043535""(regulation of blood vessel endothelial cell migration)|go:""GO:0045296""(cadherin binding)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0046058""(cAMP metabolic process)|go:""GO:0046849""(bone remodeling)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048320""(axial mesoderm formation)|go:""GO:0048870""(cell motility)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0060035""(notochord cell development)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0060444""(branching involved in mammary gland duct morphogenesis)|go:""GO:0070160""(tight junction)|go:""GO:0070309""(lens fiber cell morphogenesis)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070848""(response to growth factor)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1901491""(negative regulation of lymphangiogenesis)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1904238""(pericyte cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034263|interpro:IPR036116|interpro:IPR050449|mint:P29317|rcsb pdb:1MQB|rcsb pdb:2E8N|rcsb pdb:2K9Y|rcsb pdb:2KSO|rcsb pdb:2X10|rcsb pdb:2X11|rcsb pdb:3C8X|rcsb pdb:3CZU|rcsb pdb:3FL7|rcsb pdb:3HEI|rcsb pdb:3HPN|rcsb pdb:3KKA|rcsb pdb:3MBW|rcsb pdb:3MX0|rcsb pdb:3SKJ|rcsb pdb:4P2K|rcsb pdb:4PDO|rcsb pdb:4TRL|rcsb pdb:5EK7|rcsb pdb:5I9U|rcsb pdb:5I9V|rcsb pdb:5I9W|rcsb pdb:5I9X|rcsb pdb:5I9Y|rcsb pdb:5I9Z|rcsb pdb:5IA0|rcsb pdb:5IA1|rcsb pdb:5IA2|rcsb pdb:5IA3|rcsb pdb:5IA4|rcsb pdb:5IA5|rcsb pdb:5NJZ|rcsb pdb:5NK0|rcsb pdb:5NK1|rcsb pdb:5NK2|rcsb pdb:5NK3|rcsb pdb:5NK4|rcsb pdb:5NK5|rcsb pdb:5NK6|rcsb pdb:5NK7|rcsb pdb:5NK8|rcsb pdb:5NK9|rcsb pdb:5NKA|rcsb pdb:5NKB|rcsb pdb:5NKC|rcsb pdb:5NKD|rcsb pdb:5NKE|rcsb pdb:5NKF|rcsb pdb:5NKG|rcsb pdb:5NKH|rcsb pdb:5NKI|rcsb pdb:5NZ9|rcsb pdb:6B9L|rcsb pdb:6F7M|rcsb pdb:6F7N|rcsb pdb:6FNF|rcsb pdb:6NK1|rcsb pdb:6FNG|rcsb pdb:6FNH|rcsb pdb:6HES|rcsb pdb:6HET|rcsb pdb:6HEU|rcsb pdb:6HEV|rcsb pdb:6HEW|rcsb pdb:6HEX|rcsb pdb:6HEY|rcsb pdb:6NJZ|rcsb pdb:6NK0|rcsb pdb:6NK2|rcsb pdb:6NKP|rcsb pdb:6Q7B|rcsb pdb:6Q7C|rcsb pdb:6Q7D|rcsb pdb:6Q7E|rcsb pdb:6Q7F|rcsb pdb:6Q7G|rcsb pdb:6RW2|rcsb pdb:7B7N|rcsb pdb:7CZE|rcsb pdb:7CZF|rcsb pdb:7KJA|rcsb pdb:7KJB|rcsb pdb:7KJC|rcsb pdb:8BIN|rcsb pdb:8BIO|rcsb pdb:8BK0|rcsb pdb:8BM8|rcsb pdb:8BOC|rcsb pdb:8BOD|rcsb pdb:8BOF|rcsb pdb:8BOG|rcsb pdb:8BOH|rcsb pdb:8BOI|rcsb pdb:8BOK|rcsb pdb:8BOM|rcsb pdb:8QQY|rcsb pdb:8T9B|rcsb pdb:8TRS|rcsb pdb:8TRT|rcsb pdb:8TRV|rcsb pdb:8TV1|rcsb pdb:8TV5|rcsb pdb:8XPV|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_004422.2|efo:""Orphanet:441447""|efo:""Orphanet:98991""|efo:""Orphanet:98993""|efo:""Orphanet:98994""|dip:DIP-96N|panther:PTHR24416(orthology-group)|ensembl:ENSP00000351209.5"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:9VFikLd4ftRmEyBpY0JHdpHINT09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q15019	intact:EBI-27055528	intact:EBI-741220|intact:EBI-28986019|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3|ensembl:ENSP00000353157.3|ensembl:ENSP00000375832.2|ensembl:ENSP00000375834.2|ensembl:ENSP00000385172.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001269901.1|refseq:NP_001269902.1|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:NP_001307960.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSG00000168385.18(gene)|ensembl:ENST00000360051.7(transcript)|ensembl:ENST00000391971.7(transcript)|ensembl:ENST00000391973.6(transcript)|ensembl:ENST00000402092.6(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0002036""(regulation of L-glutamate import across plasma membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005886""(plasma membrane)|go:""GO:0005930""(axoneme)|go:""GO:0005940""(septin ring)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008104""(protein localization)|go:""GO:0009986""(cell surface)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0030154""(cell differentiation)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0030496""(midbody)|go:""GO:0031105""(septin complex)|go:""GO:0032153""(cell division site)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042802""(identical protein binding)|go:""GO:0045171""(intercellular bridge)|go:""GO:0045296""(cadherin binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060170""(ciliary membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0061640""(cytoskeleton-dependent cytokinesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097227""(sperm annulus)|go:""GO:0097730""(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|rcsb pdb:7M6J|reactome:R-HSA-5620912|refseq:XP_016859694.1|refseq:XP_016859695.1|dip:DIP-38220N|panther:PTHR18884(orthology-group)"	-	-	crc64:12CCBBE30806F92F	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q07065	intact:EBI-27055528	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265.4|intact:EBI-21353377	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_006816.2|ensembl:ENSG00000136026.14(gene)|ensembl:ENST00000378026.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005811""(lipid droplet)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042599""(lamellar body)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270|panther:PTHR45161(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q92597	intact:EBI-27055528	intact:EBI-716486|uniprotkb:O15207|uniprotkb:Q9NYR6|uniprotkb:Q9UK29|uniprotkb:Q6IBG2|uniprotkb:B3KR80|uniprotkb:B7Z446|ensembl:ENSP00000319977.8|ensembl:ENSP00000404854.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ndrg1_human(display_long)|uniprotkb:N-myc downstream-regulated gene 1 protein(gene name synonym)|uniprotkb:Differentiation-related gene 1 protein(gene name synonym)|uniprotkb:Reducing agents and tunicamycin-responsive protein(gene name synonym)|uniprotkb:Nickel-specific induction protein Cap43(gene name synonym)|uniprotkb:Rit42(gene name synonym)|uniprotkb:NDRG1(gene name)|psi-mi:NDRG1(display_short)|uniprotkb:CAP43(gene name synonym)|uniprotkb:DRG1(gene name synonym)|uniprotkb:RTP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000104419.17(gene)|ensembl:ENST00000323851.13(transcript)|ensembl:ENST00000414097.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007165""(signal transduction)|go:""GO:0008017""(microtubule binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010038""(response to metal ion)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032287""(peripheral nervous system myelin maintenance)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045576""(mast cell activation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|interpro:IPR004142(Ndr)|interpro:IPR029058|mint:Q92597|rcsb pdb:6ZMM|reactome:R-HSA-6803205|refseq:NP_001128714.1|refseq:NP_001245361.1|refseq:NP_001245362.1|refseq:NP_006087.2|efo:""Orphanet:99950""|panther:PTHR11034(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:zeyNRbcgqPcHXkqwE42s1e9uEqI9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P63027	intact:EBI-27055528	intact:EBI-520113|uniprotkb:P19065|uniprotkb:Q9BUC2|ensembl:ENSP00000314214.6	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:vamp2_human(display_long)|uniprotkb:Synaptobrevin-2(gene name synonym)|uniprotkb:VAMP2(gene name)|psi-mi:VAMP2(display_short)|uniprotkb:SYB2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_055047.2|ensembl:ENSG00000220205.10(gene)|ensembl:ENST00000316509.11(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0009749""(response to glucose)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016079""(synaptic vesicle exocytosis)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043308""(eosinophil degranulation)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0045202""(synapse)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0060203""(clathrin-sculpted glutamate transport vesicle membrane)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0061025""(membrane fusion)|go:""GO:0061202""(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070032""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:""GO:0070033""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:""GO:0070044""(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:""GO:0070083""(clathrin-sculpted monoamine transport vesicle membrane)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:1902259""(regulation of delayed rectifier potassium channel activity)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:P63027|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:7UDC|reactome:R-HSA-1445148|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-199992|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-449836|reactome:R-HSA-5250955|reactome:R-HSA-5250958|reactome:R-HSA-5250981|reactome:R-HSA-5250982|reactome:R-HSA-5250989|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|dip:DIP-39072N|panther:PTHR45701(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:uuuJXsI5sr7fzjxuBhSYDHJZp9M9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q14160	intact:EBI-27055528	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000349486.2|ensembl:ENSP00000484041.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_056171.3|refseq:NP_874365.3|ensembl:ENSG00000180900.20(gene)|ensembl:ENSG00000274287.4(gene)|ensembl:ENST00000356994.7(transcript)|ensembl:ENST00000612204.4(transcript)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001843""(neural tube closure)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016080""(synaptic vesicle targeting)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0034750""(Scrib-APC-beta-catenin complex)|go:""GO:0035089""(establishment of apical/basal cell polarity)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042060""(wound healing)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043615""(astrocyte cell migration)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060561""(apoptotic process involved in morphogenesis)|go:""GO:0060603""(mammary gland duct morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098793""(presynapse)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098968""(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099147""(extrinsic component of postsynaptic density membrane)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|interpro:IPR050614|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|rcsb pdb:7QRS|rcsb pdb:7QRT|rcsb pdb:7QS8|rcsb pdb:7QS9|rcsb pdb:7QSA|rcsb pdb:7QSB|rcsb pdb:7QTO|rcsb pdb:7QTP|rcsb pdb:7QTU|rcsb pdb:8B82|rcsb pdb:8B87|rcsb pdb:8B8O|rcsb pdb:8B9T|rcsb pdb:8BIA|rcsb pdb:8BJ0|rcsb pdb:8CD3|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270|dip:DIP-31259N|panther:PTHR23119(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:xHNrql5wX2JZV+9YxFGM7gm1/CY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q04721	intact:EBI-27055528	intact:EBI-2652733|uniprotkb:Q5T3X7|uniprotkb:Q99734|uniprotkb:Q9H240|ensembl:ENSP00000256646.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:notc2_human(display_long)|uniprotkb:NOTCH2(gene name)|psi-mi:NOTCH2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:261629""|efo:""Orphanet:955""|ensembl:ENSG00000134250.21(gene)|ensembl:ENST00000256646.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001709""(cell fate determination)|go:""GO:0001947""(heart looping)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0002315""(marginal zone B cell differentiation)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0006915""(apoptotic process)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007411""(axon guidance)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009986""(cell surface)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010838""(positive regulation of keratinocyte proliferation)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035622""(intrahepatic bile duct development)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042060""(wound healing)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043011""(myeloid dendritic cell differentiation)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0046849""(bone remodeling)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0060413""(atrial septum morphogenesis)|go:""GO:0060674""(placenta blood vessel development)|go:""GO:0061073""(ciliary body morphogenesis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0072014""(proximal tubule development)|go:""GO:0072015""(podocyte development)|go:""GO:0072104""(glomerular capillary formation)|go:""GO:0072574""(hepatocyte proliferation)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1990705""(cholangiocyte proliferation)|go:""GO:2001204""(regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022336|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:Q04721|rcsb pdb:2OO4|rcsb pdb:5MWB|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-2197563|reactome:R-HSA-2979096|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013695|refseq:NP_001186930.1|refseq:NP_077719.2|ensembl:ENSP00000256646.2|panther:PTHR45836(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:aXdQSGMwNJ7K0tA2kc3rRFysbIc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P29966	intact:EBI-27055528	intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_002347.5|ensembl:ENSG00000277443.3(gene)|ensembl:ENST00000612661.2(transcript)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006915""(apoptotic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007015""(actin filament organization)|go:""GO:0007417""(central nervous system development)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0021915""(neural tube development)|go:""GO:0022008""(neurogenesis)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042585""(germinal vesicle)|go:""GO:0042802""(identical protein binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997|panther:PTHR14353(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P54105	intact:EBI-27055528	intact:EBI-724693|uniprotkb:Q0VDK6|uniprotkb:Q9NRD2|uniprotkb:Q9NRD3|uniprotkb:B2RCS9|ensembl:ENSP00000433919.1|ensembl:ENSP00000434311.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:icln_human(display_long)|uniprotkb:Chloride conductance regulatory protein ICln(gene name synonym)|uniprotkb:Chloride channel, nucleotide sensitive 1A(gene name synonym)|uniprotkb:Chloride ion current inducer protein(gene name synonym)|uniprotkb:Reticulocyte pICln(gene name synonym)|uniprotkb:CLNS1A(gene name)|psi-mi:CLNS1A(display_short)|uniprotkb:ICLN(gene name synonym)|uniprotkb:CLCI(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001284.1|refseq:NP_001298128.1|refseq:NP_001298129.1|refseq:NP_001298130.1|refseq:NP_001298131.1|ensembl:ENSG00000074201.9(gene)|ensembl:ENST00000525428.6(transcript)|ensembl:ENST00000528364.1(transcript)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006821""(chloride transport)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0034709""(methylosome)|go:""GO:0034715""(pICln-Sm protein complex)|go:""GO:0045292""(mRNA cis splicing, via spliceosome)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR003521(Nucleotide-sensitive chloride conductance regulator)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039924|mint:P54105|rcsb pdb:6V0O|reactome:R-HSA-191859|dip:DIP-44185N|panther:PTHR21399(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:dGx9UwPj9VBp1CiPTRCXnT3IYt89606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P18031	intact:EBI-27055528	intact:EBI-968788|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4|ensembl:ENSP00000360683.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N|ensembl:ENSG00000196396.10(gene)|ensembl:ENST00000371621.5(transcript)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0003723""(RNA binding)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0009968""(negative regulation of signal transduction)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030162""(regulation of proteolysis)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031904""(endosome lumen)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033157""(regulation of intracellular protein transport)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035791""(platelet-derived growth factor receptor-beta signaling pathway)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045296""(cadherin binding)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071732""(cellular response to nitric oxide)|go:""GO:0097443""(sorting endosome)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903896""(positive regulation of IRE1-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904753""(negative regulation of vascular associated smooth muscle cell migration)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990264""(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:""GO:2000353""(positive regulation of endothelial cell apoptotic process)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1AAX|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2F6Z|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:2NT7|rcsb pdb:2NTA|rcsb pdb:2QBP|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2QBS|rcsb pdb:2VEU|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2ZMM|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:3EB1|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QDV|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:6OMY|rcsb pdb:6PFW|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:6XE8|rcsb pdb:6XEF|rcsb pdb:6XEA|rcsb pdb:6XED|rcsb pdb:6XEE|rcsb pdb:6XEG|rcsb pdb:7FQM|rcsb pdb:7FQN|rcsb pdb:7FQO|rcsb pdb:7FQP|rcsb pdb:7FQQ|rcsb pdb:7FQR|rcsb pdb:7FQS|rcsb pdb:7FQT|rcsb pdb:7FQU|rcsb pdb:7FQV|rcsb pdb:7FQW|rcsb pdb:7FQX|rcsb pdb:7FQY|rcsb pdb:7FQZ|rcsb pdb:7FRE|rcsb pdb:7FRF|rcsb pdb:7FRG|rcsb pdb:7FRH|rcsb pdb:7FRI|rcsb pdb:7FRJ|rcsb pdb:7FRK|rcsb pdb:7FRL|rcsb pdb:7FRM|rcsb pdb:7FRN|rcsb pdb:7FRO|rcsb pdb:7FRP|rcsb pdb:7FRQ|rcsb pdb:7FRR|rcsb pdb:7FRS|rcsb pdb:7FRT|rcsb pdb:7FRU|rcsb pdb:7GS7|rcsb pdb:7GS8|rcsb pdb:7GS9|rcsb pdb:7GSA|rcsb pdb:7GSB|rcsb pdb:7GSC|rcsb pdb:7GSD|rcsb pdb:7GSE|rcsb pdb:7GSF|rcsb pdb:7GSG|rcsb pdb:7GSH|rcsb pdb:7GSI|rcsb pdb:7GSJ|rcsb pdb:7GSK|rcsb pdb:7GSL|rcsb pdb:7GSM|rcsb pdb:7GSN|rcsb pdb:7GSO|rcsb pdb:7GSQ|rcsb pdb:7GSR|rcsb pdb:7GST|rcsb pdb:7GSU|rcsb pdb:7GSV|rcsb pdb:7GSW|rcsb pdb:7GSX|rcsb pdb:7GSY|rcsb pdb:7GSZ|rcsb pdb:7GT0|rcsb pdb:7GT1|rcsb pdb:7GT2|rcsb pdb:7GT3|rcsb pdb:7GT4|rcsb pdb:7GT5|rcsb pdb:7GTI|rcsb pdb:7GT6|rcsb pdb:7GT7|rcsb pdb:7GT8|rcsb pdb:7GT9|rcsb pdb:7GTA|rcsb pdb:7GTB|rcsb pdb:7GTC|rcsb pdb:7GTD|rcsb pdb:7GTE|rcsb pdb:7GTF|rcsb pdb:7GTG|rcsb pdb:7GTH|rcsb pdb:7GTJ|rcsb pdb:7GTK|rcsb pdb:7GTL|rcsb pdb:7GTM|rcsb pdb:7GTN|rcsb pdb:7GTO|rcsb pdb:7GTP|rcsb pdb:7GTQ|rcsb pdb:7GTR|rcsb pdb:7GTS|rcsb pdb:7GTT|rcsb pdb:7GTU|rcsb pdb:7GTV|rcsb pdb:7GTW|rcsb pdb:7GTX|rcsb pdb:7GTY|rcsb pdb:7GTZ|rcsb pdb:7GU0|rcsb pdb:7GU1|rcsb pdb:7GU2|rcsb pdb:7GU3|rcsb pdb:7GU4|rcsb pdb:7GU5|rcsb pdb:7GU6|rcsb pdb:7GU7|rcsb pdb:7GU8|rcsb pdb:7GU9|rcsb pdb:7GUA|rcsb pdb:7GUB|rcsb pdb:7GUC|rcsb pdb:7KEN|rcsb pdb:7KEY|rcsb pdb:7KLX|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MKZ|rcsb pdb:7MM1|rcsb pdb:7MN7|rcsb pdb:7MN9|rcsb pdb:7MNA|rcsb pdb:7MNB|rcsb pdb:7MNC|rcsb pdb:7MND|rcsb pdb:7MNE|rcsb pdb:7MNF|rcsb pdb:7MOU|rcsb pdb:7MOV|rcsb pdb:7MOW|rcsb pdb:7RIN|rcsb pdb:7S4F|rcsb pdb:8DU7|rcsb pdb:8EXI|rcsb pdb:8EXJ|rcsb pdb:8EXK|rcsb pdb:8EXM|rcsb pdb:8EXN|rcsb pdb:8EYA|rcsb pdb:8EYB|rcsb pdb:8EYC|rcsb pdb:8F88|rcsb pdb:8G65|rcsb pdb:8G67|rcsb pdb:8G68|rcsb pdb:8G69|rcsb pdb:8G6A|rcsb pdb:8SKL|rcsb pdb:8U1E|rcsb pdb:8XOY|rcsb pdb:9C66|rcsb pdb:9CYO|rcsb pdb:9CYP|rcsb pdb:9CYQ|rcsb pdb:9CYR|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-77387|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-9860927|panther:PTHR46047(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O96013	intact:EBI-27055528	intact:EBI-713738|uniprotkb:Q8N4E1|uniprotkb:Q8NCH5|uniprotkb:Q8NDE3|uniprotkb:Q9BU33|uniprotkb:Q9ULS8|uniprotkb:B4DGG6|ensembl:ENSP00000351049.2|ensembl:ENSP00000353625.3|ensembl:ENSP00000469413.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pak4_human(display_long)|uniprotkb:p21-activated kinase 4(gene name synonym)|uniprotkb:PAK4(gene name)|psi-mi:PAK4(display_short)|uniprotkb:KIAA1142(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001014831.1|refseq:NP_001014832.1|refseq:NP_001014834.1|refseq:NP_001014835.1|refseq:NP_005875.1|ensembl:ENSG00000130669.17(gene)|ensembl:ENST00000358301.7(transcript)|ensembl:ENST00000360442.8(transcript)|ensembl:ENST00000593690.5(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006915""(apoptotic process)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007165""(signal transduction)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016477""(cell migration)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0060996""(dendritic spine development)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|rcsb pdb:4O0X|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|interpro:IPR051931|mint:O96013|rcsb pdb:2BVA|rcsb pdb:2CDZ|rcsb pdb:2J0I|rcsb pdb:2OV2|rcsb pdb:2Q0N|rcsb pdb:2X4Z|rcsb pdb:4APP|rcsb pdb:4FIE|rcsb pdb:4FIF|rcsb pdb:4FIG|rcsb pdb:4FIH|rcsb pdb:4FII|rcsb pdb:4FIJ|rcsb pdb:4JDH|rcsb pdb:4JDI|rcsb pdb:4JDJ|rcsb pdb:4JDK|rcsb pdb:4L67|rcsb pdb:4NJD|rcsb pdb:4O0V|rcsb pdb:4O0Y|rcsb pdb:4XBR|rcsb pdb:4XBU|rcsb pdb:5BMS|rcsb pdb:5I0B|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:5VED|rcsb pdb:5VEE|rcsb pdb:5VEF|rcsb pdb:5XVA|rcsb pdb:5XVF|rcsb pdb:5XVG|rcsb pdb:5ZJW|rcsb pdb:6WLX|rcsb pdb:6WLY|rcsb pdb:7CMB|rcsb pdb:7CP3|rcsb pdb:7CP4|rcsb pdb:7S46|rcsb pdb:7S47|rcsb pdb:7S48|rcsb pdb:8AHG|rcsb pdb:8AHH|rcsb pdb:8AHI|rcsb pdb:8YHK|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|refseq:XP_011524618.1|refseq:XP_011524619.1|refseq:XP_011524620.1|refseq:XP_011524621.1|refseq:XP_011524622.1|dip:DIP-39742N|panther:PTHR48015(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:8i8hHt/Taj+czkueFRAMhdiMkYw9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8IZ21	intact:EBI-27055528	intact:EBI-3938822|uniprotkb:Q68DD4|uniprotkb:B9ZVW0|uniprotkb:Q9H395|uniprotkb:Q9H6X0|uniprotkb:Q8N384|uniprotkb:Q6NUN6|uniprotkb:Q9H8W6|uniprotkb:D3DPM3|uniprotkb:A2APK6|ensembl:ENSP00000362945.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:phar4_human(display_long)|uniprotkb:PHACTR4(gene name)|psi-mi:PHACTR4(display_short)|uniprotkb:PRO2963(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001041648.1|refseq:NP_076412.3|refseq:XP_016857657.1|refseq:XP_016857662.1|dip:DIP-47323N|ensembl:ENSG00000204138.13(gene)|ensembl:ENST00000373839.8(transcript)|go:""GO:0001755""(neural crest cell migration)|go:""GO:0001843""(neural tube closure)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0043085""(positive regulation of catalytic activity)|go:""GO:0048484""(enteric nervous system development)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0061386""(closure of optic fissure)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:2001045""(negative regulation of integrin-mediated signaling pathway)|interpro:IPR004018(RPEL repeat)|mint:Q8IZ21|panther:PTHR12751(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:RaPU7amt8Ztkr4p8+PMGSs5Pw4I9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q15334	intact:EBI-27055528	intact:EBI-299979|uniprotkb:O00188|uniprotkb:Q58F11|uniprotkb:Q86UK6|uniprotkb:A7MBM7|ensembl:ENSP00000321537.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:l2gl1_human(display_long)|uniprotkb:DLG4(gene name synonym)|uniprotkb:LLGL1(gene name)|psi-mi:LLGL1(display_short)|uniprotkb:Human homolog to the D-lgl gene protein(gene name synonym)|uniprotkb:Hugl-1(gene name synonym)|uniprotkb:HUGL(gene name synonym)|uniprotkb:HUGL1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000131899.13(gene)|ensembl:ENST00000316843.9(transcript)|go:""GO:0000137""(Golgi cis cisterna)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0007409""(axonogenesis)|go:""GO:0008593""(regulation of Notch signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030424""(axon)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032878""(regulation of establishment or maintenance of cell polarity)|go:""GO:0045159""(myosin II binding)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0051294""(establishment of spindle orientation)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR000664(""Lethal(2) giant larvae protein"")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q15334|refseq:NP_004131.3|panther:PTHR10241(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:VqlrgKVnWmXyx1lvnpRe9hRQD0Q9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P20020	intact:EBI-27055528	intact:EBI-5279998|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|ensembl:ENSP00000392043.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000070961.17(gene)|efo:""Orphanet:528084""|ensembl:ENST00000428670.8(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0003056""(regulation of vascular associated smooth muscle contraction)|go:""GO:0005388""(P-type calcium transporter activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0015085""(calcium ion transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030501""(positive regulation of bone mineralization)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042995""(cell projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051481""(negative regulation of cytosolic calcium ion concentration)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098684""(photoreceptor ribbon synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1990034""(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P20020|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9662360|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_011536709.1|refseq:XP_016874847.1|panther:PTHR24093(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O95292	intact:EBI-27055528	intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR10809(orthology-group)|dip:DIP-39816N|efo:""Orphanet:209335""|efo:""Orphanet:803""|ensembl:ENSG00000124164.16(gene)|ensembl:ENST00000475243.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019899""(enzyme binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0044830""(modulation by host of viral RNA genome replication)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046725""(negative regulation by virus of viral protein levels in host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0090114""(COPII-coated vesicle budding)|go:""GO:0090158""(endoplasmic reticulum membrane organization)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|refseq:NP_001182606.1|refseq:NP_004729.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9ULE6	intact:EBI-27055528	intact:EBI-3957166|uniprotkb:B2RMS1|uniprotkb:B9EGC6|uniprotkb:Q5JTK7|uniprotkb:Q5JTK8|ensembl:ENST00000263563|ensembl:ENSP00000263563.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pald_human(display_long)|uniprotkb:PALD1(gene name)|psi-mi:PALD1(display_short)|uniprotkb:KIAA1274(gene name synonym)|uniprotkb:PALD(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011537939.1|refseq:XP_011537940.1|refseq:NP_055246.2|refseq:XP_016871561.1|ensembl:ENSG00000107719.10(gene)|ensembl:ENST00000263563.7(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR029021|interpro:IPR050561|mint:Q9ULE6|panther:PTHR23339(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Qn2qNHC/kC0rsLk68yNNZUrFmc49606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q658P3	intact:EBI-27055528	intact:EBI-3933105|uniprotkb:Q86SF6|uniprotkb:Q9NVB5|uniprotkb:A8K6E3|uniprotkb:Q8TF03|uniprotkb:Q8TDP3|uniprotkb:Q4VBR2|uniprotkb:Q8NEW6|uniprotkb:Q53SQ8|uniprotkb:Q7Z389|uniprotkb:Q4ZG36|ensembl:ENSP00000376818.2|ensembl:ENSP00000376819.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:stea3_human(display_long)|uniprotkb:STEAP3(gene name)|psi-mi:STEAP3(display_short)|uniprotkb:TSAP6(gene name synonym)|uniprotkb:Dudulin-2(gene name synonym)|uniprotkb:Six-transmembrane epithelial antigen of prostate 3(gene name synonym)|uniprotkb:Tumor suppressor-activated pathway protein 6(gene name synonym)|uniprotkb:pHyde(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000115107.20(gene)|ensembl:ENST00000393106.6(transcript)|ensembl:ENST00000393107.2(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005886""(plasma membrane)|go:""GO:0006826""(iron ion transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0008823""(""cupric reductase (NADH) activity"")|go:""GO:0009306""(protein secretion)|go:""GO:0010008""(endosome membrane)|go:""GO:0015677""(copper ion import)|go:""GO:0020037""(heme binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0052851""(""ferric-chelate reductase (NADPH) activity"")|go:""GO:0071949""(FAD binding)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR028939|interpro:IPR036291|interpro:IPR051267|mint:Q658P3|rcsb pdb:2VNS|rcsb pdb:2VQ3|reactome:R-HSA-6803204|reactome:R-HSA-9013148|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9035034|reactome:R-HSA-917977|refseq:NP_001008410.1|refseq:NP_060704.2|refseq:NP_619543.2|refseq:NP_878919.2|refseq:XP_006712677.1|refseq:XP_006712678.1|refseq:XP_011509705.1|efo:""Orphanet:300298""|panther:PTHR14239(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:fZmXHidOHx0fIw1WYbsyliQcZVA9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9HB21	intact:EBI-27055528	intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986.3|ensembl:ENSP00000376547.3|ensembl:ENSP00000394416.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:XP_005270073.1|refseq:XP_005270078.1|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679.15(gene)|ensembl:ENST00000368990.8(transcript)|ensembl:ENST00000392799.7(transcript)|ensembl:ENST00000433307.2(transcript)|go:""GO:0001553""(luteinization)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008209""(androgen metabolic process)|go:""GO:0008210""(estrogen metabolic process)|go:""GO:0009791""(post-embryonic development)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0031529""(ruffle organization)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033327""(Leydig cell differentiation)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0043325""(phosphatidylinositol-3,4-bisphosphate binding)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060021""(roof of mouth development)|go:""GO:0060325""(face morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070301""(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR051707|mint:Q9HB21|rcsb pdb:1EAZ|reactome:R-HSA-1660499|panther:PTHR14336(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P51149	intact:EBI-27055528	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062.3|ensembl:ENSP00000501618.1|ensembl:ENSP00000502000.1|ensembl:ENSP00000502088.1|ensembl:ENSP00000502486.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000075785.14(gene)|ensembl:ENST00000265062.8(transcript)|ensembl:ENST00000674589.1(transcript)|ensembl:ENST00000675342.1(transcript)|ensembl:ENST00000675497.1(transcript)|ensembl:ENST00000676214.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0019003""(GDP binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0036466""(synaptic vesicle recycling via endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045453""(bone resorption)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048524""(positive regulation of viral process)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090383""(phagosome acidification)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0097208""(alveolar lamellar body)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:1903542""(negative regulation of exosomal secretion)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1905366""(negative regulation of intralumenal vesicle formation)|go:""GO:1905394""(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:3LAW|rcsb pdb:6IYB|rcsb pdb:6WCW|rcsb pdb:7F6J|rcsb pdb:8KB8|rcsb pdb:8ZQ3|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|refseq:NP_004628.4|efo:""Orphanet:99936""|dip:DIP-39879N|panther:PTHR47981(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P05023	intact:EBI-27055528	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|ensembl:ENSP00000295598.5|intact:EBI-10963133	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR43294(orthology-group)|ensembl:ENSG00000163399.16(gene)|ensembl:ENST00000295598.10(transcript)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0005391""(""P-type sodium:potassium-exchanging transporter activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0007231""(osmosensory signaling pathway)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016791""(phosphatase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030315""(T-tubule)|go:""GO:0030424""(axon)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031090""(organelle membrane)|go:""GO:0031402""(sodium ion binding)|go:""GO:0031947""(negative regulation of glucocorticoid biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0045823""(positive regulation of heart contraction)|go:""GO:0045989""(positive regulation of striated muscle contraction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060342""(photoreceptor inner segment membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086009""(membrane repolarization)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903416""(response to glycoside)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990239""(steroid hormone binding)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|interpro:IPR050510|mint:P05023|rcsb pdb:7E1Z|rcsb pdb:7E20|rcsb pdb:7E21|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|efo:""Orphanet:521414""|efo:""Orphanet:564178"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9ULK5	intact:EBI-27055528	intact:EBI-1054279|uniprotkb:Q5T212|uniprotkb:D3DVE9|ensembl:ENSP00000357040.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:vang2_human(display_long)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Strabismus 1(gene name synonym)|uniprotkb:Loop-tail protein 1 homolog(gene name synonym)|uniprotkb:VANGL2(gene name)|psi-mi:VANGL2(display_short)|uniprotkb:KIAA1215(gene name synonym)|uniprotkb:STB1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:563609""|efo:""Orphanet:563612""|ensembl:ENSG00000162738.8(gene)|ensembl:ENST00000368061.3(transcript)|go:""GO:0001736""(establishment of planar polarity)|go:""GO:0001843""(neural tube closure)|go:""GO:0001947""(heart looping)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0035787""(cell migration involved in kidney development)|go:""GO:0036514""(dopaminergic neuron axon guidance)|go:""GO:0036515""(serotonergic neuron axon guidance)|go:""GO:0045176""(apical protein localization)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q9ULK5|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7R2M|rcsb pdb:7R2T|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_065068.1|refseq:XP_005245414.1|refseq:XP_011508106.1|panther:PTHR20886(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:x6JAZMeK90S/m6+oSp/W1tN1Cjc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q14254	intact:EBI-27055528	intact:EBI-348613|ensembl:ENSP00000378368.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:flot2_human(display_long)|uniprotkb:FLOT2(gene name)|psi-mi:FLOT2(display_short)|uniprotkb:ESA1(gene name synonym)|uniprotkb:M17S1(gene name synonym)|uniprotkb:Epidermal surface antigen(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004466.2|ensembl:ENSG00000132589.16(gene)|ensembl:ENST00000394908.9(transcript)|go:""GO:0001931""(uropod)|go:""GO:0002020""(protease binding)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0008544""(epidermis development)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016600""(flotillin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031982""(vesicle)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0044860""(protein localization to plasma membrane raft)|go:""GO:0045661""(regulation of myoblast differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098937""(anterograde dendritic transport)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1902992""(negative regulation of amyloid precursor protein catabolic process)|go:""GO:1903905""(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:Q14254|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9696264|reactome:R-HSA-9696273|refseq:XP_016879883.1|refseq:XP_016879884.1|panther:PTHR13806(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:P9htlLzTYk+eDKKesqCEPe/1BJA9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q86Y07	intact:EBI-27055528	intact:EBI-1207615|uniprotkb:Q49AK9|uniprotkb:Q53EU9|uniprotkb:Q86Y08|uniprotkb:Q86Y09|uniprotkb:Q86Y10|uniprotkb:Q86Y11|uniprotkb:Q86Y12|uniprotkb:Q8IXI5|uniprotkb:Q99987|uniprotkb:Q53S39|uniprotkb:Q53S77|uniprotkb:Q53TU1|uniprotkb:B4DKL0|uniprotkb:D6W5D4|uniprotkb:D6W5D6|ensembl:ENSP00000342381.4|ensembl:ENSP00000408002.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:vrk2_human(display_long)|uniprotkb:VRK2(gene name)|psi-mi:VRK2(display_short)|uniprotkb:Vaccinia-related kinase 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011531394.1|refseq:XP_006712153.1|refseq:XP_006712154.1|refseq:XP_006712155.1|refseq:XP_006712156.1|refseq:NP_001123952.1|refseq:NP_001123953.1|refseq:NP_001123954.1|refseq:NP_001123955.1|refseq:NP_006287.2|refseq:NP_001275765.1|refseq:NP_001275766.1|refseq:NP_001275767.1|refseq:NP_001275768.1|ensembl:ENSG00000028116.18(gene)|ensembl:ENST00000340157.9(transcript)|ensembl:ENST00000435505.6(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000659""(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR050235|mint:Q86Y07|rcsb pdb:2V62|rcsb pdb:5UU1|rcsb pdb:6NCG|rcsb pdb:8Q1Z|rcsb pdb:9FET|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:XP_005264597.1|panther:PTHR11909(orthology-group)|refseq:XP_016860347.1|refseq:XP_016860348.1|refseq:XP_016860349.1|refseq:XP_016860350.1|refseq:XP_016860351.1|refseq:XP_016860352.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:sDftNP5rKcTUJgpJAcbJsNzag0I9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q15006	intact:EBI-27055528	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_055488.1|ensembl:ENSG00000104412.8(gene)|ensembl:ENST00000220853.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0042406""(extrinsic component of endoplasmic reticulum membrane)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072546""(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|interpro:IPR055217|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|rcsb pdb:8EOI|rcsb pdb:8J0N|rcsb pdb:8J0O|rcsb pdb:8S9S|rcsb pdb:9C7V|panther:PTHR12760(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P51648	intact:EBI-27055528	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643.6|ensembl:ENSP00000461916.2|ensembl:ENSP00000463637.1|ensembl:ENSP00000500092.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR43570(orthology-group)|efo:""Orphanet:816""|ensembl:ENSG00000072210.19(gene)|ensembl:ENST00000176643.11(transcript)|ensembl:ENST00000579855.5(transcript)|ensembl:ENST00000581518.6(transcript)|ensembl:ENST00000672357.1(transcript)|go:""GO:0004028""(3-chloroallyl aldehyde dehydrogenase activity)|go:""GO:0004029""(""aldehyde dehydrogenase (NAD+) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006081""(aldehyde metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006714""(sesquiterpenoid metabolic process)|go:""GO:0007417""(central nervous system development)|go:""GO:0007422""(peripheral nervous system development)|go:""GO:0008544""(epidermis development)|go:""GO:0033306""(phytol metabolic process)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046458""(hexadecanal metabolic process)|go:""GO:0046577""(long-chain-alcohol oxidase activity)|go:""GO:0050061""(""long-chain fatty aldehyde dehydrogenase (NAD+) activity"")|go:""GO:0052814""(""medium-chain fatty aldehyde dehydrogenase (NAD+) activity"")|interpro:IPR012394(""Aldehyde dehydrogenase NAD(P)-dependent"")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9845614|refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q86X29	intact:EBI-27055528	intact:EBI-1056946|uniprotkb:O00112|uniprotkb:O00426|uniprotkb:Q6ZT80|uniprotkb:Q9UQL3|uniprotkb:E9PHD4|uniprotkb:Q8NBM0|uniprotkb:Q9BT33|uniprotkb:A6NDW3|ensembl:ENSP00000480821.1|intact:EBI-10982122|uniprotkb:B4DKL4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:lsr_human(display_long)|uniprotkb:Angulin-1(gene name synonym)|uniprotkb:ILDR3(gene name synonym)|uniprotkb:LSR(gene name)|psi-mi:LSR(display_short)|uniprotkb:LISCH(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_991403.1|refseq:NP_001247418.1|refseq:NP_001247419.1|refseq:NP_057009.3|refseq:NP_991404.1|ensembl:ENSG00000105699.17(gene)|ensembl:ENST00000621372.4(transcript)|go:""GO:0001889""(liver development)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0030054""(cell junction)|go:""GO:0034361""(very-low-density lipoprotein particle)|go:""GO:0034362""(low-density lipoprotein particle)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042627""(chylomicron)|go:""GO:0060856""(establishment of blood-brain barrier)|go:""GO:0061436""(establishment of skin barrier)|go:""GO:0061689""(tricellular tight junction)|go:""GO:0061833""(protein localization to tricellular tight junction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070160""(tight junction)|go:""GO:1904274""(tricellular tight junction assembly)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008664(LISCH7)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR051874|mint:Q86X29|reactome:R-HSA-8964038|reactome:R-HSA-8964046|panther:PTHR15923(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:jCmNdVxzNBHEpWjKNqyq5e6yEjs9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O00429	intact:EBI-27055528	intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|ensembl:ENSP00000450399.1|uniprotkb:G8JLD5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:330050""|efo:""Orphanet:98673""|ensembl:ENSG00000087470.21(gene)|ensembl:ENST00000549701.6(transcript)|go:""GO:0000266""(mitochondrial fission)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005777""(peroxisome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005903""(brush border)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006897""(endocytosis)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0008289""(lipid binding)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016559""(peroxisome fission)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0048312""(intracellular distribution of mitochondria)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048511""(rhythmic process)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051259""(protein complex oligomerization)|go:""GO:0060047""(heart contraction)|go:""GO:0070585""(protein localization to mitochondrion)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0090141""(positive regulation of mitochondrial fission)|go:""GO:0090149""(mitochondrial membrane fission)|go:""GO:0160040""(mitocytosis)|go:""GO:1900063""(regulation of peroxisome organization)|go:""GO:1901524""(regulation of mitophagy)|go:""GO:1903578""(regulation of ATP metabolic process)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR045063|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|rcsb pdb:8T1H|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|dip:DIP-42704N|panther:PTHR11566(orthology-group)"	-	-	crc64:F9521A376B785B71	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9BZF1	intact:EBI-27055528	intact:EBI-2684038|uniprotkb:Q52LQ3|uniprotkb:Q9P277|uniprotkb:Q8WXP8|uniprotkb:A8K1T2|uniprotkb:E9PE66|uniprotkb:E9PE68|uniprotkb:Q68D75|ensembl:ENSP00000261183.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:osbl8_human(display_long)|uniprotkb:OSBP10(gene name synonym)|uniprotkb:KIAA1451(gene name synonym)|uniprotkb:ORP8(gene name synonym)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001003712.1|refseq:NP_065892.1|refseq:XP_005268678.1|refseq:XP_006719287.1|refseq:NP_001306581.1|refseq:NP_001306584.1|dip:DIP-56130N|ensembl:ENSG00000091039.17(gene)|ensembl:ENST00000261183.8(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005548""(phospholipid transporter activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0010891""(negative regulation of triglyceride storage)|go:""GO:0015485""(cholesterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0016020""(membrane)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032541""(cortical endoplasmic reticulum)|go:""GO:0036150""(phosphatidylserine acyl-chain remodeling)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0090204""(protein localization to nuclear pore)|go:""GO:0140343""(phosphatidylserine transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q9BZF1|rcsb pdb:1V88|rcsb pdb:5U77|rcsb pdb:5U78|rcsb pdb:8P7A|reactome:R-HSA-1482801|panther:PTHR10972(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:KwZ5DFeGTIM3p/yP3XBNgr/v3O09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q86W92	intact:EBI-27055528	intact:EBI-1045582|uniprotkb:O75336|uniprotkb:Q86X70|uniprotkb:Q9NY03|uniprotkb:Q9ULJ0|ensembl:ENSP00000314724.8	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:lipb1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1(gene name synonym)|uniprotkb:PPFIBP1(gene name)|psi-mi:PPFIBP1(display_short)|uniprotkb:KIAA1230(gene name synonym)|uniprotkb:hSGT2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001185844.1|refseq:NP_001185845.1|refseq:NP_003613.3|refseq:NP_803193.2|dip:DIP-42195N|ensembl:ENSG00000110841.14(gene)|ensembl:ENST00000318304.12(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0048786""(presynaptic active zone)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q86W92|reactome:R-HSA-388844|reactome:R-HSA-9725370|panther:PTHR12587(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:PIoFJHaX4lvBJ0EYcascPgJP8bI9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9UKE5	intact:EBI-27055528	intact:EBI-1051794|intact:EBI-1762540|uniprotkb:O60298|uniprotkb:Q8WUY7|uniprotkb:Q9UKD8|uniprotkb:Q9UKD9|uniprotkb:Q9UKE0|uniprotkb:Q9UKE1|uniprotkb:Q9UKE2|uniprotkb:Q9UKE3|uniprotkb:Q9UKE4|intact:EBI-1968916|uniprotkb:A8K4U1|uniprotkb:D3DNQ6|uniprotkb:A7E2A3|ensembl:ENSP00000399511.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:tnik_human(display_long)|uniprotkb:TNIK(gene name)|psi-mi:TNIK(display_short)|uniprotkb:KIAA0551(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000154310.17(gene)|ensembl:ENST00000436636.7(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030033""(microvillus assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0048814""(regulation of dendrite morphogenesis)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR051700|mint:Q9UKE5|rcsb pdb:2X7F|rcsb pdb:5AX9|rcsb pdb:5CWZ|rcsb pdb:5D7A|rcsb pdb:6RA5|rcsb pdb:6RA7|rcsb pdb:7XZQ|rcsb pdb:7XZR|rcsb pdb:8WM0|rcsb pdb:8X88|reactome:R-HSA-2559580|refseq:NP_001155032.1|refseq:NP_001155033.1|refseq:NP_001155034.1|refseq:NP_001155035.1|refseq:NP_001155036.1|refseq:NP_001155037.1|refseq:NP_001155038.1|refseq:NP_055843.1|dip:DIP-37562N|efo:""Orphanet:88616""|panther:PTHR48015(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:b+FNQZpz2ZX+wcVH9wuqOgZQ/cE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P49802	intact:EBI-27055528	intact:EBI-1754797|uniprotkb:Q8TD66|uniprotkb:Q8TD67|uniprotkb:Q9UNU7|uniprotkb:Q9Y6B9|uniprotkb:Q5T3H4|uniprotkb:Q8WW09|ensembl:ENSP00000404399.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:rgs7_human(display_long)|uniprotkb:RGS7(gene name)|psi-mi:RGS7(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001269702.1|refseq:NP_001269704.1|refseq:NP_001269707.1|refseq:NP_002915.3|ensembl:ENSG00000182901.18(gene)|ensembl:ENST00000440928.6(transcript)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0031681""(G-protein beta-subunit binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0043005""(neuron projection)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045471""(response to ethanol)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:1901381""(positive regulation of potassium ion transmembrane transport)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036284|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|interpro:IPR040759|interpro:IPR044926|interpro:IPR047016|interpro:IPR047017|mint:P49802|rcsb pdb:2A72|rcsb pdb:2D9J|rcsb pdb:7EWP|rcsb pdb:7EWR|rcsb pdb:7SHF|reactome:R-HSA-418594|reactome:R-HSA-6814122|refseq:XP_005273275.1|dip:DIP-40869N|panther:PTHR45746(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:epeNPVu00d27S9hlaKto1/bKwhI9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O15126	intact:EBI-27055528	intact:EBI-954338|uniprotkb:O43587|uniprotkb:Q96BX1|uniprotkb:Q96QK5|uniprotkb:Q6FG23|ensembl:ENSP00000481022.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:scam1_human(display_long)|uniprotkb:SCAMP1(gene name)|psi-mi:SCAMP1(display_short)|uniprotkb:SCAMP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004857.4|refseq:NP_001277158.1|ensembl:ENSG00000085365.18(gene)|ensembl:ENST00000621999.5(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0055038""(recycling endosome membrane)|interpro:IPR007273(SCAMP)|mint:O15126|reactome:R-HSA-6798695|panther:PTHR10687(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Utuf4fnpMHS2yG4zfccdB2enfxI9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9C0B5	intact:EBI-27055528	intact:EBI-2799626|uniprotkb:Q8TAK8|uniprotkb:Q9H923|uniprotkb:Q9UFI7|uniprotkb:Q6ZMF0|uniprotkb:Q2TGF0|ensembl:ENSP00000287169.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:zdhc5_human(display_long)|uniprotkb:KIAA1748(gene name synonym)|uniprotkb:ZNF375(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 5(gene name synonym)|uniprotkb:Zinc finger protein 375(gene name synonym)|uniprotkb:ZDHHC5(gene name)|psi-mi:ZDHHC5(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011543201.1|refseq:XP_011543202.1|refseq:XP_011543203.1|refseq:NP_056272.2|ensembl:ENSG00000156599.11(gene)|ensembl:ENST00000287169.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0016020""(membrane)|go:""GO:0016409""(palmitoyltransferase activity)|go:""GO:0018345""(protein palmitoylation)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0030425""(dendrite)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0062208""(positive regulation of pattern recognition receptor signaling pathway)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099091""(postsynaptic specialization, intracellular component)|go:""GO:0140639""(positive regulation of pyroptotic inflammatory response)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905171""(positive regulation of protein localization to phagocytic vesicle)|interpro:IPR001594(Zinc finger, DHHC-type)|mint:Q9C0B5|reactome:R-HSA-9694548|panther:PTHR12349(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:4EKCQeKXifPU/7fv6uPuHE7b1rU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y2A7	intact:EBI-27055528	intact:EBI-389845|uniprotkb:O60329|uniprotkb:Q53QN5|uniprotkb:Q53S94|uniprotkb:Q53Y35|ensembl:ENSP00000355348.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:nckp1_human(display_long)|uniprotkb:NCKAP1(gene name)|psi-mi:NCKAP1(display_short)|uniprotkb:HEM2(gene name synonym)|uniprotkb:KIAA0587(gene name synonym)|uniprotkb:NAP1(gene name synonym)|uniprotkb:p125Nap1(gene name synonym)|uniprotkb:Membrane-associated protein HEM-2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR12093(orthology-group)|refseq:NP_038464.1|refseq:NP_995314.1|ensembl:ENSG00000061676.16(gene)|ensembl:ENST00000361354.9(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001726""(ruffle)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006915""(apoptotic process)|go:""GO:0007417""(central nervous system development)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031209""(SCAR complex)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031941""(filamentous actin)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000601""(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR019137|mint:Q9Y2A7|rcsb pdb:3P8C|rcsb pdb:4N78|rcsb pdb:7USC|rcsb pdb:7USD|rcsb pdb:7USE|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|dip:DIP-31119N"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:xj4ySr6cf374UbE/gfuxMx1X0tw9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q12955	intact:EBI-27055528	intact:EBI-2691178|uniprotkb:Q5VXD5|intact:EBI-7224084|intact:MINT-1182900|uniprotkb:Q13484|uniprotkb:B4DIL1|uniprotkb:E9PE32|uniprotkb:Q5CZH9|uniprotkb:Q7Z3G4|uniprotkb:B1AQT2|uniprotkb:Q9H0P5|ensembl:ENSP00000280772.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ank3_human(display_long)|uniprotkb:Ankyrin-G(gene name synonym)|uniprotkb:ANK3(gene name)|psi-mi:ANK3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:356996""|dip:DIP-49017N|ensembl:ENSG00000151150.22(gene)|ensembl:ENST00000280772.7(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007409""(axonogenesis)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010650""(positive regulation of cell communication by electrical coupling)|go:""GO:0010765""(positive regulation of sodium ion transport)|go:""GO:0010960""(magnesium ion homeostasis)|go:""GO:0014704""(intercalated disc)|go:""GO:0014731""(spectrin-associated cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019228""(neuronal action potential)|go:""GO:0030018""(Z disc)|go:""GO:0030315""(T-tubule)|go:""GO:0030425""(dendrite)|go:""GO:0030507""(spectrin binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0033268""(node of Ranvier)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0042383""(sarcolemma)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043034""(costamere)|go:""GO:0043194""(axon initial segment)|go:""GO:0043266""(regulation of potassium ion transport)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0045838""(positive regulation of membrane potential)|go:""GO:0071286""(cellular response to magnesium ion)|go:""GO:0071709""(membrane assembly)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0072660""(maintenance of protein location in plasma membrane)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0099612""(protein localization to axon)|go:""GO:1900827""(positive regulation of membrane depolarization during cardiac muscle cell action potential)|go:""GO:1902260""(negative regulation of delayed rectifier potassium channel activity)|go:""GO:2000651""(positive regulation of sodium ion transmembrane transporter activity)|go:""GO:2001259""(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR036770|interpro:IPR037971|interpro:IPR040745|interpro:IPR051165|mint:Q12955|rcsb pdb:4O6X|reactome:R-HSA-445095|reactome:R-HSA-6807878|refseq:NP_001140.2|refseq:NP_001191332.1|refseq:NP_001191333.1|refseq:NP_066267.2|panther:PTHR24133(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:k03Sz+VxForOlnJt8P9i8KAFzss9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P98172	intact:EBI-27055528	intact:EBI-538287|uniprotkb:D3DVU0|ensembl:ENSP00000204961.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:efnb1_human(display_long)|uniprotkb:EPH-related receptor tyrosine kinase ligand 2(gene name synonym)|uniprotkb:EFL3(gene name synonym)|uniprotkb:EFNB1(gene name)|psi-mi:EFNB1(display_short)|uniprotkb:EFL-3(gene name synonym)|uniprotkb:EPLG2(gene name synonym)|uniprotkb:LERK2(gene name synonym)|uniprotkb:ELK ligand(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR11304(orthology-group)|ensembl:ENSG00000090776.6(gene)|ensembl:ENST00000204961.5(transcript)|go:""GO:0001755""(neural crest cell migration)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007411""(axon guidance)|go:""GO:0009880""(embryonic pattern specification)|go:""GO:0009986""(cell surface)|go:""GO:0031295""(T cell costimulation)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P98172|rcsb pdb:6THG|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|refseq:NP_004420.1|efo:""Orphanet:1520"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:s9RYPWXKQ2QMzvfGluiliH3YC3s9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P14923	intact:EBI-27055528	intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113.5|ensembl:ENSP00000377507.1|ensembl:ENSP00000377508.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:158687""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:34217""|ensembl:ENSG00000173801.17(gene)|ensembl:ENST00000310706.9(transcript)|ensembl:ENST00000393930.5(transcript)|ensembl:ENST00000393931.8(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0002159""(desmosome assembly)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0014704""(intercalated disc)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030018""(Z disc)|go:""GO:0030057""(desmosome)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0043588""(skin development)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050982""(detection of mechanical stimulus)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071603""(endothelial cell-cell adhesion)|go:""GO:0071665""(gamma-catenin-TCF7L2 complex)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0086073""(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:""GO:0086083""(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0106006""(cytoskeletal protein-membrane anchor activity)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9833576|refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_016880079.1|dip:DIP-36235N|panther:PTHR45976(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q5T2T1	intact:EBI-27055528	intact:EBI-2514004|uniprotkb:B2RCC9|uniprotkb:Q5T2T0|uniprotkb:B5MDZ3|uniprotkb:Q8IY28|uniprotkb:D3DRW3|uniprotkb:B4DWL9|ensembl:ENSP00000337907.5|ensembl:ENSP00000364871.3|ensembl:ENSP00000364884.1|ensembl:ENSP00000507917.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mpp7_human(display_long)|uniprotkb:MPP7(gene name)|psi-mi:MPP7(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011517639.1|refseq:NP_775767.2|refseq:NP_001305099.1|ensembl:ENSG00000150054.19(gene)|ensembl:ENST00000337532.9(transcript)|ensembl:ENST00000375719.7(transcript)|ensembl:ENST00000375732.5(transcript)|ensembl:ENST00000683449.1(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005938""(cell cortex)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030054""(cell junction)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0097025""(MPP7-DLG1-LIN7 complex)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035599|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|interpro:IPR050716|mint:Q5T2T1|rcsb pdb:3LRA|rcsb pdb:3O46|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|panther:PTHR23122(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:QYVCkD5zsnTsCd7YsYsbQY8L7fU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P05556	intact:EBI-27055528	intact:EBI-703066|intact:EBI-4289597|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5|ensembl:ENSP00000303351.3|ensembl:ENSP00000379350.2|ensembl:ENSP00000398029.2|ensembl:ENSP00000404546.3|ensembl:ENSP00000502882.1|ensembl:ENSP00000503546.1|ensembl:ENSP00000503916.1|ensembl:ENSP00000504205.1|ensembl:ENSP00000504444.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|ensembl:ENSG00000150093.20(gene)|ensembl:ENST00000302278.8(transcript)|ensembl:ENST00000396033.6(transcript)|ensembl:ENST00000417122.7(transcript)|ensembl:ENST00000437302.6(transcript)|ensembl:ENST00000677999.1(transcript)|ensembl:ENST00000678701.1(transcript)|ensembl:ENST00000678943.1(transcript)|ensembl:ENST00000678952.1(transcript)|dip:DIP-312N|ensembl:ENST00000678989.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001726""(ruffle)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002020""(protease binding)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006968""(cellular defense response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007517""(muscle organ development)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008305""(integrin complex)|go:""GO:0008354""(germ cell migration)|go:""GO:0008542""(visual learning)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010710""(regulation of collagen catabolic process)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0014704""(intercalated disc)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030175""(filopodium)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031623""(receptor internalization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0033631""(cell-cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034665""(integrin alpha1-beta1 complex)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0034667""(integrin alpha3-beta1 complex)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0034674""(integrin alpha5-beta1 complex)|go:""GO:0034675""(integrin alpha6-beta1 complex)|go:""GO:0034677""(integrin alpha7-beta1 complex)|go:""GO:0034678""(integrin alpha8-beta1 complex)|go:""GO:0034679""(integrin alpha9-beta1 complex)|go:""GO:0034680""(integrin alpha10-beta1 complex)|go:""GO:0034681""(integrin alpha11-beta1 complex)|go:""GO:0034682""(integrin alphav-beta1 complex)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043197""(dendritic spine)|go:""GO:0043235""(receptor complex)|go:""GO:0043236""(laminin binding)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045743""(positive regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048626""(myoblast fate specification)|go:""GO:0048675""(axon extension)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051951""(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0055037""(recycling endosome)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060912""(cardiac cell fate specification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097386""(glial cell projection)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150053""(cerebellar climbing fiber to Purkinje cell synapse)|go:""GO:0150103""(reactive gliosis)|go:""GO:1900748""(positive regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901979""(regulation of inward rectifier potassium channel activity)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905806""(regulation of synapse pruning)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|rcsb pdb:7CEB|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEC|rcsb pdb:7NWL|rcsb pdb:7NXD|rcsb pdb:8RPQ|rcsb pdb:9CKV|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9634597|reactome:R-HSA-9679191|reactome:R-HSA-9725554|reactome:R-HSA-9830674|reactome:R-HSA-9860927|panther:PTHR10082(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q99618	intact:EBI-27055528	intact:EBI-739534|uniprotkb:A8K5V6|uniprotkb:D3DUS6|ensembl:ENSP00000442068.1|ensembl:ENSP00000446339.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:cdca3_human(display_long)|uniprotkb:CDCA3(gene name)|psi-mi:CDCA3(display_short)|uniprotkb:Trigger of mitotic entry protein 1(gene name synonym)|uniprotkb:Gene-rich cluster protein C8(gene name synonym)|uniprotkb:C8(gene name synonym)|uniprotkb:GRCC8(gene name synonym)|uniprotkb:TOME1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_112589.1|ensembl:ENSG00000111665.12(gene)|ensembl:ENST00000535406.5(transcript)|ensembl:ENST00000538862.7(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005912""(adherens junction)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0051301""(cell division)|interpro:IPR038832|mint:Q99618|refseq:NP_001284532.1|refseq:NP_001284533.1|refseq:NP_001317948.1|panther:PTHR34756(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:UmhACVP83jo9/xqP7qDSSvKgiAo9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:A0FGR8	intact:EBI-27055528	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0006897""(endocytosis)|go:""GO:0008429""(phosphatidylethanolamine binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0044232""(organelle membrane contact site)|go:""GO:0045296""(cadherin binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0140268""(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|interpro:IPR051634|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-9845576|panther:PTHR45761(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q92575	intact:EBI-27055528	intact:EBI-723441|uniprotkb:Q4ZG56|uniprotkb:Q8IYM5|intact:EBI-28978946|uniprotkb:A8K9W4|ensembl:ENSP00000272638.9	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ubxn4_human(display_long)|uniprotkb:Erasin(gene name synonym)|uniprotkb:UBXN4(gene name)|psi-mi:UBXN4(display_short)|uniprotkb:KIAA0242(gene name synonym)|uniprotkb:UBXDC1(gene name synonym)|uniprotkb:UBXD2(gene name synonym)|uniprotkb:UBX domain-containing protein 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_055422.1|ensembl:ENSG00000144224.17(gene)|ensembl:ENST00000272638.14(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0036503""(ERAD pathway)|interpro:IPR001012(UBX)|interpro:IPR029071|interpro:IPR036249|mint:Q92575|rcsb pdb:2KXJ|panther:PTHR46424(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:rWCmtHlje9EFw7YVQQNJBBH4bLE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8IWC1	intact:EBI-27055528	intact:EBI-1050284|uniprotkb:A6NCZ7|uniprotkb:A2A2J0|uniprotkb:A6NHR4|uniprotkb:Q5JXI5|uniprotkb:Q5JXI6|uniprotkb:Q9H9M8|uniprotkb:Q6P2S1|uniprotkb:B4DWD2|uniprotkb:H7BY77|ensembl:ENSP00000318086.9	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ma7d3_human(display_long)|uniprotkb:MAP7D3(gene name)|psi-mi:MAP7D3(display_short)|uniprotkb:MDP3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001166987.1|refseq:NP_001166988.1|refseq:NP_078873.2|ensembl:ENSG00000129680.16(gene)|ensembl:ENST00000316077.14(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015631""(tubulin binding)|go:""GO:0016020""(membrane)|go:""GO:0046785""(microtubule polymerization)|interpro:IPR008604(E-MAP-115)|interpro:IPR051483|mint:Q8IWC1|panther:PTHR15073(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:9WwXvs5DT9zh5c7DC27VuemEeU09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q01974	intact:EBI-27055528	intact:EBI-6422642|ensembl:ENSP00000364860.3|uniprotkb:Q59GF5|uniprotkb:Q9HB61|uniprotkb:Q9HAY7|uniprotkb:Q5SPI5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ror2_human(display_long)|uniprotkb:NTRKR2(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase, receptor-related 2(gene name synonym)|uniprotkb:ROR2(gene name)|psi-mi:ROR2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000169071.15(gene)|ensembl:ENST00000375708.4(transcript)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009986""(cell surface)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014002""(astrocyte development)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0030282""(bone mineralization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030539""(male genitalia development)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043235""(receptor complex)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051968""(positive regulation of synaptic transmission, glutamatergic)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0150045""(regulation of synaptic signaling by nitric oxide)|go:""GO:1905517""(macrophage migration)|interpro:IPR000001(Kringle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR016247(Tyrosine-protein kinase transmembrane receptor ROR)|interpro:IPR018056|interpro:IPR020067|interpro:IPR036179|interpro:IPR036790|interpro:IPR038178|interpro:IPR050122|mint:Q01974|rcsb pdb:3ZZW|rcsb pdb:4GT4|rcsb pdb:6OSH|rcsb pdb:6OSN|rcsb pdb:6OSV|rcsb pdb:9FSE|reactome:R-HSA-4086400|reactome:R-HSA-5140745|refseq:NP_001305133.1|refseq:NP_004551.2|efo:""Orphanet:1507""|efo:""Orphanet:572385""|panther:PTHR24416(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:gEEAvjiYUC5dWEtyCE0eb0K+MTU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9P0I2	intact:EBI-27055528	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046.2|ensembl:ENSP00000474771.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_060917.1|ensembl:ENSG00000125037.13(gene)|ensembl:ENST00000245046.7(transcript)|ensembl:ENST00000470827.3(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072546""(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|mint:Q9P0I2|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|rcsb pdb:8EOI|rcsb pdb:8J0N|rcsb pdb:8J0O|rcsb pdb:8S9S|rcsb pdb:9C7V|reactome:R-HSA-8980692|panther:PTHR13116(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q15836	intact:EBI-27055528	intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666.6	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004772.1|ensembl:ENSG00000049245.13(gene)|ensembl:ENST00000054666.11(transcript)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0030133""(transport vesicle)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061025""(membrane fusion)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:1903531""(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-56422N|panther:PTHR45701(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P35613	intact:EBI-27055528	intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|ensembl:ENSG00000172270.22(gene)|ensembl:ENST00000333511.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0003407""(neural retina development)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007566""(embryo implantation)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045494""(photoreceptor cell maintenance)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0046689""(response to mercury ion)|go:""GO:0046697""(decidualization)|go:""GO:0051591""(response to cAMP)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:1904466""(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:3QR2|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|rcsb pdb:7DAA|rcsb pdb:7DCE|rcsb pdb:7XY8|rcsb pdb:8XEJ|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-9749641|refseq:XP_016882662.1|dip:DIP-50310N|panther:PTHR10075(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8NDI1	intact:EBI-27055528	intact:EBI-2689720|uniprotkb:Q9NWI9|uniprotkb:Q6QNV2|uniprotkb:Q6NX72|uniprotkb:Q53TV6|uniprotkb:Q6PIT3|uniprotkb:Q53TG7|uniprotkb:Q580X2|uniprotkb:O94977|ensembl:ENSP00000263991.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ehbp1_human(display_long)|uniprotkb:KIAA0903(gene name synonym)|uniprotkb:NACSIN(gene name synonym)|uniprotkb:EHBP1(gene name)|psi-mi:EHBP1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011531015.1|refseq:XP_011531016.1|refseq:XP_011531017.1|refseq:NP_001136086.1|refseq:NP_001136087.1|refseq:NP_001136088.1|refseq:NP_056067.2|refseq:XP_016859136.1|refseq:XP_016859137.1|refseq:XP_016859138.1|refseq:XP_005264282.1|refseq:XP_005264283.1|refseq:XP_005264284.1|rcsb pdb:6ZSJ|ensembl:ENSG00000115504.15(gene)|ensembl:ENST00000263991.9(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0015031""(protein transport)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR019448|interpro:IPR022735|interpro:IPR036872|interpro:IPR050540|mint:Q8NDI1|rcsb pdb:2D89|rcsb pdb:6ZSH|rcsb pdb:6ZSI|refseq:XP_016859132.1|refseq:XP_016859133.1|refseq:XP_016859140.1|panther:PTHR23167(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:sDcegXBYi8eQp7KReaysxBy3Ogc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P49757	intact:EBI-27055528	intact:EBI-915016|uniprotkb:Q6NUQ7|uniprotkb:Q86SY1|uniprotkb:Q8WW73|uniprotkb:Q9UBG1|uniprotkb:Q9UEQ4|uniprotkb:Q9UKE8|uniprotkb:Q9UKE9|uniprotkb:Q9UKF0|uniprotkb:Q9UQJ4|uniprotkb:B4E2B1|ensembl:ENSP00000347169.3|ensembl:ENSP00000451300.1|uniprotkb:B1P2N7|uniprotkb:B1P2N8|uniprotkb:B1P2N9|uniprotkb:B1P2N5|uniprotkb:B1P2N6|intact:EBI-28966915	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:numb_human(display_long)|uniprotkb:Protein S171(gene name synonym)|uniprotkb:NUMB(gene name)|psi-mi:NUMB(display_short)|uniprotkb:C14orf41(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001307043.1|refseq:NP_001005743.1|refseq:NP_001005744.1|refseq:NP_001005745.1|refseq:NP_003735.3|ensembl:ENSG00000133961.22(gene)|ensembl:ENST00000355058.7(transcript)|ensembl:ENST00000555238.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005925""(focal adhesion)|go:""GO:0007409""(axonogenesis)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0010008""(endosome membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0021670""(lateral ventricle development)|go:""GO:0021849""(neuroblast division in subventricular zone)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034332""(adherens junction organization)|go:""GO:0045177""(apical part of cell)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P49757|rcsb pdb:5NJJ|rcsb pdb:5NJK|reactome:R-HSA-2122948|reactome:R-HSA-437239|reactome:R-HSA-5610780|reactome:R-HSA-5632684|reactome:R-HSA-9725554|dip:DIP-37981N|panther:PTHR47368(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:X+CHBhp67o6ROnf86RCtXlCAaF49606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9NNW5	intact:EBI-27055528	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:wdr6_human(display_long)|uniprotkb:WD repeat-containing protein 6(gene name synonym)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_060501.3|panther:PTHR14344(orthology-group)|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252.19(gene)|ensembl:ENST00000608424.6(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002130""(wobble position ribose methylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0030488""(tRNA methylation)|go:""GO:0070314""(G1 to G0 transition)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR051973|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9ULF5	intact:EBI-27055528	intact:EBI-2823223|uniprotkb:A8K5C6|uniprotkb:Q3MJA4|uniprotkb:Q6DKH6|uniprotkb:Q68CR5|uniprotkb:Q9Y3Z1|uniprotkb:B4DGU0|ensembl:ENSP00000352655.5|ensembl:ENSP00000386766.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:s39aa_human(display_long)|uniprotkb:SLC39A10(gene name)|psi-mi:SLC39A10(display_short)|uniprotkb:KIAA1265(gene name synonym)|uniprotkb:ZIP10(gene name synonym)|uniprotkb:Solute carrier family 39 member 10(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 10(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011509806.1|refseq:XP_011509807.1|refseq:XP_011509808.1|refseq:NP_001120729.1|refseq:NP_065075.1|refseq:XP_005246746.2|ensembl:ENSG00000196950.14(gene)|ensembl:ENST00000359634.10(transcript)|ensembl:ENST00000409086.7(transcript)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0002903""(negative regulation of B cell apoptotic process)|go:""GO:0005385""(zinc ion transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030003""(intracellular monoatomic cation homeostasis)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0050861""(positive regulation of B cell receptor signaling pathway)|go:""GO:0071577""(zinc ion transmembrane transport)|go:""GO:0071578""(zinc ion import across plasma membrane)|go:""GO:0140410""(""monoatomic cation:bicarbonate symporter activity"")|interpro:IPR003689(Zinc/iron permease)|interpro:IPR050799|mint:Q9ULF5|reactome:R-HSA-442380|panther:PTHR12191(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:j7A/tPe/lJCOscfBZhF1mSe99k09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q7Z2K8	intact:EBI-27055528	intact:EBI-11152848|uniprotkb:Q96PZ4|uniprotkb:Q8ND74|uniprotkb:C9JM70|ensembl:ENSP00000305839.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:grin1_human(display_long)|uniprotkb:GPRIN1(gene name)|psi-mi:GPRIN1(display_short)|uniprotkb:KIAA1893(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_443131.2|ensembl:ENSG00000169258.7(gene)|ensembl:ENST00000303991.5(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0030426""(growth cone)|go:""GO:0031175""(neuron projection development)|go:""GO:0051219""(phosphoprotein binding)|interpro:IPR026646|interpro:IPR032745|mint:Q7Z2K8|reactome:R-HSA-9022699|panther:PTHR15718(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:jrKC+dySA+Jej1vv29IWm01SUsY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P53985	intact:EBI-27055528	intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|ensembl:ENSP00000358640.4|ensembl:ENSP00000397106.2|ensembl:ENSP00000399104.2|ensembl:ENSP00000416167.2|ensembl:ENSP00000441065.1|ensembl:ENSP00000485688.1|ensembl:ENSP00000486000.1|ensembl:ENSP00000505879.1|uniprotkb:Q49A45	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000155380.13(gene)|ensembl:ENSG00000281917.4(gene)|ensembl:ENST00000369626.8(transcript)|ensembl:ENST00000429288.2(transcript)|ensembl:ENST00000443580.6(transcript)|ensembl:ENST00000458229.6(transcript)|ensembl:ENST00000538576.5(transcript)|ensembl:ENST00000628110.2(transcript)|ensembl:ENST00000630362.4(transcript)|ensembl:ENST00000679803.1(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007098""(centrosome cycle)|go:""GO:0008028""(monocarboxylic acid transmembrane transporter activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0015129""(lactate transmembrane transporter activity)|go:""GO:0015130""(mevalonate transmembrane transporter activity)|go:""GO:0015141""(succinate transmembrane transporter activity)|go:""GO:0015650""(""lactate:proton symporter activity"")|go:""GO:0015718""(monocarboxylic acid transport)|go:""GO:0015728""(mevalonate transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0030054""(cell junction)|go:""GO:0032094""(response to food)|go:""GO:0035879""(plasma membrane lactate transport)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042867""(pyruvate catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0046943""(carboxylic acid transmembrane transporter activity)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0051780""(behavioral response to nutrient)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0071422""(succinate transmembrane transport)|go:""GO:0097159""(obsolete organic cyclic compound binding)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901475""(pyruvate transmembrane transport)|go:""GO:1905039""(carboxylic acid transmembrane transport)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|interpro:IPR050327|mint:P53985|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|rcsb pdb:7YR5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-9749641|refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|efo:""Orphanet:165991""|efo:""Orphanet:171690""|efo:""Orphanet:438075""|panther:PTHR11360(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q5VV42	intact:EBI-27055528	intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695.4|ensembl:ENSP00000367873.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	"psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:""tRNA-t(6)A37 methylthiotransferase""(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_060244.2|ensembl:ENSG00000145996.11(gene)|ensembl:ENST00000274695.8(transcript)|ensembl:ENST00000378610.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0016020""(membrane)|go:""GO:0035598""(""tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase activity"")|go:""GO:0035600""(tRNA methylthiolation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0061712""(""obsolete tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase"")|go:""GO:1990145""(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315|panther:PTHR11918(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q16513	intact:EBI-27055528	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243.20(gene)|ensembl:ENST00000370521.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004698""(calcium,diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004699""(diacylglycerol-dependent, calcium-independent serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0010631""(epithelial cell migration)|go:""GO:0016301""(kinase activity)|go:""GO:0016604""(nuclear body)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030496""(midbody)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045296""(cadherin binding)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051301""(cell division)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|reactome:R-HSA-9856530|panther:PTHR24356(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O43402	intact:EBI-27055528	intact:EBI-741841|uniprotkb:C9JB21|ensembl:ENSP00000253457.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_006058.1|refseq:NP_001135760.1|ensembl:ENSG00000131148.9(gene)|ensembl:ENST00000253457.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0016020""(membrane)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072546""(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|mint:O43402|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|rcsb pdb:8EOI|rcsb pdb:8J0N|rcsb pdb:8J0O|rcsb pdb:8S9S|rcsb pdb:9C7V|panther:PTHR12941(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O95573	intact:EBI-27055528	intact:EBI-1190822|uniprotkb:Q60I92|uniprotkb:Q8IUM9|intact:EBI-21359981|ensembl:ENSP00000350012.3|ensembl:ENSP00000375918.3|ensembl:ENSP00000504861.1|ensembl:ENSP00000504907.1|ensembl:ENSP00000505400.1|ensembl:ENSP00000505654.1|ensembl:ENSP00000505793.1|ensembl:ENSP00000505856.1|ensembl:ENSP00000505940.1|ensembl:ENSP00000506361.1|ensembl:ENSP00000506468.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:acsl3_human(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:ACSL3(gene name)|psi-mi:ACSL3(display_short)|uniprotkb:ACS3(gene name synonym)|uniprotkb:FACL3(gene name synonym)|uniprotkb:LACS3(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase 3(gene name synonym)|uniprotkb:Medium-chain acyl-CoA ligase Acsl3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004448.2|refseq:NP_976251.1|refseq:XP_016859073.1|panther:PTHR43272(orthology-group)|ensembl:ENSG00000123983.15(gene)|ensembl:ENST00000357430.8(transcript)|ensembl:ENST00000392066.7(transcript)|ensembl:ENST00000679514.1(transcript)|ensembl:ENST00000679558.1(transcript)|ensembl:ENST00000680147.1(transcript)|ensembl:ENST00000680251.1(transcript)|ensembl:ENST00000680395.1(transcript)|ensembl:ENST00000680684.1(transcript)|ensembl:ENST00000680921.1(transcript)|ensembl:ENST00000681383.1(transcript)|ensembl:ENST00000681697.1(transcript)|go:""GO:0001676""(long-chain fatty acid metabolic process)|go:""GO:0004467""(long-chain fatty acid-CoA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0031956""(medium-chain fatty acid-CoA ligase activity)|go:""GO:0034379""(very-low-density lipoprotein particle assembly)|go:""GO:0035336""(long-chain fatty-acyl-CoA metabolic process)|go:""GO:0035338""(long-chain fatty-acyl-CoA biosynthetic process)|go:""GO:0042998""(positive regulation of Golgi to plasma membrane protein transport)|go:""GO:0044539""(long-chain fatty acid import into cell)|go:""GO:0047676""(arachidonate-CoA ligase activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051047""(positive regulation of secretion)|go:""GO:0090433""(palmitoyl-CoA ligase activity)|go:""GO:2001247""(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR042099|mint:O95573|reactome:R-HSA-434313|reactome:R-HSA-75876"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:L5tCBPOlL45uh0aUFi4algZQ5nY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8IUW5	intact:EBI-27055528	intact:EBI-11343385|uniprotkb:Q8NBK1|ensembl:ENSP00000313385.4|ensembl:ENSP00000398778.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:rell1_human(display_long)|uniprotkb:RELL1(gene name)|psi-mi:RELL1(display_short)|uniprotkb:PSEC0162(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001078868.1|refseq:NP_001078869.1|ensembl:ENSG00000181826.10(gene)|ensembl:ENST00000314117.8(transcript)|ensembl:ENST00000454158.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:1900745""(positive regulation of p38MAPK cascade)|interpro:IPR022248|interpro:IPR042315|mint:Q8IUW5|panther:PTHR31037(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:in0yR+RiPdt1RmVWn5x9ad0kcws9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P52799	intact:EBI-27055528	intact:EBI-7532268|intact:MINT-3019741|uniprotkb:Q5JV56|ensembl:ENSP00000493716.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:efnb2_human(display_long)|uniprotkb:EFNB2(gene name)|psi-mi:EFNB2(display_short)|uniprotkb:EPLG5(gene name synonym)|uniprotkb:HTKL(gene name synonym)|uniprotkb:LERK5(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 5(gene name synonym)|uniprotkb:HTK ligand(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004084.1|ensembl:ENSG00000125266.8(gene)|ensembl:ENST00000646441.1(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001945""(lymph vessel development)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007411""(axon guidance)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010839""(negative regulation of keratinocyte proliferation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0030425""(dendrite)|go:""GO:0031295""(T cell costimulation)|go:""GO:0034332""(adherens junction organization)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043616""(keratinocyte proliferation)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048514""(blood vessel morphogenesis)|go:""GO:0048845""(venous blood vessel morphogenesis)|go:""GO:0050920""(regulation of chemotaxis)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0072178""(nephric duct morphogenesis)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099054""(presynapse assembly)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1903849""(positive regulation of aorta morphogenesis)|go:""GO:2000727""(positive regulation of cardiac muscle cell differentiation)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P52799|rcsb pdb:2HLE|rcsb pdb:2I85|rcsb pdb:2VSK|rcsb pdb:2VSM|rcsb pdb:2WO2|rcsb pdb:3GXU|rcsb pdb:4UF7|rcsb pdb:6P7Y|rcsb pdb:6PDL|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|dip:DIP-46378N|panther:PTHR11304(orthology-group)"	-	-	comment:mint|function:Binds to the receptor tyrosine kinases EPHB4 and EPHA3. May play a role in constraining the orientation of longitudinally projecting axons	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Ie9xTJNgMD4VdbCiT9rJf1XCgqE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9HAU0	intact:EBI-27055528	intact:EBI-945934|uniprotkb:Q86ST7|uniprotkb:A0JP03|uniprotkb:Q8N3K6|uniprotkb:Q96DY9|uniprotkb:Q9BVR4|uniprotkb:Q9C0H7|uniprotkb:Q9H924|uniprotkb:Q9NVK8|uniprotkb:B4DGS1|uniprotkb:F5H0I0|uniprotkb:E9PHQ3|uniprotkb:Q6NSF8|ensembl:ENSP00000299275.6	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pkha5_human(display_long)|uniprotkb:PLEKHA5(gene name)|psi-mi:PLEKHA5(display_short)|uniprotkb:KIAA1686(gene name synonym)|uniprotkb:PEPP2(gene name synonym)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001137293.2|refseq:NP_061885.2|refseq:NP_001177789.2|refseq:NP_001243399.1|refseq:NP_001243716.1|refseq:XP_005253457.1|ensembl:ENSG00000052126.17(gene)|ensembl:ENST00000299275.10(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0010314""(phosphatidylinositol-5-phosphate binding)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0061458""(reproductive system development)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0080025""(phosphatidylinositol-3,5-bisphosphate binding)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|mint:Q9HAU0|rcsb pdb:2DKP|reactome:R-HSA-1660499|refseq:XP_016874992.1|refseq:XP_011519019.1|panther:PTHR12752(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:22W2zdIwTLw4nNRh0dHasYDCLK49606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O75396	intact:EBI-27055528	intact:EBI-1058865|uniprotkb:A8K1G0|ensembl:ENSP00000463393.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004883.3|ensembl:ENSG00000265808.4(gene)|ensembl:ENST00000578049.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0015031""(protein transport)|go:""GO:0030133""(transport vesicle)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042470""(melanosome)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048280""(vesicle fusion with Golgi apparatus)|go:""GO:1902902""(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:8HR0|reactome:R-HSA-1236974|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|dip:DIP-50458N|panther:PTHR45837(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:DRKtD169T9eYZ2kFufLapidvcKs9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q92667	intact:EBI-27055528	intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736.3|ensembl:ENSP00000443139.1|ensembl:ENSP00000459895.1|ensembl:ENSP00000459968.1|ensembl:ENSP00000478212.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|panther:PTHR22948(orthology-group)|ensembl:ENSG00000121057.13(gene)|ensembl:ENST00000337714.8(transcript)|ensembl:ENST00000539273.5(transcript)|ensembl:ENST00000571629.5(transcript)|ensembl:ENST00000572557.5(transcript)|ensembl:ENST00000621116.4(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|interpro:IPR047367|interpro:IPR047368|interpro:IPR050621|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q96J84	intact:EBI-27055528	intact:EBI-3988456|uniprotkb:Q5W0F8|uniprotkb:Q5XKC6|uniprotkb:Q7Z696|uniprotkb:Q7Z7N8|uniprotkb:Q8TB15|uniprotkb:Q9H9N1|uniprotkb:Q9NVA5|ensembl:ENSP00000352138.6	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:kirr1_human(display_long)|uniprotkb:KIRREL1(gene name)|psi-mi:KIRREL1(display_short)|uniprotkb:KIRREL(gene name synonym)|uniprotkb:Kin of irregular chiasm-like protein 1(gene name synonym)|uniprotkb:NEPH1(gene name synonym)|uniprotkb:Nephrin-like protein 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001273278.1|refseq:NP_060710.3|refseq:XP_005245362.1|ensembl:ENSG00000183853.18(gene)|ensembl:ENST00000359209.11(transcript)|go:""GO:0003094""(glomerular filtration)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0017022""(myosin binding)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031253""(cell projection membrane)|go:""GO:0043198""(dendritic shaft)|go:""GO:0045121""(membrane raft)|go:""GO:0045217""(cell-cell junction maintenance)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0097017""(renal protein absorption)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR051275|mint:Q96J84|reactome:R-HSA-373753|panther:PTHR11640(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:AZjf1PpCzbkuNJngJUPYa7bWYAo9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9H2J7	intact:EBI-27055528	intact:EBI-11343466|uniprotkb:E7ESJ5|uniprotkb:B7Z2P7|uniprotkb:A8K592|uniprotkb:Q9H9F5|ensembl:ENSP00000266682.5|ensembl:ENSP00000505286.1|ensembl:ENSP00000505485.1|ensembl:ENSP00000505789.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:s6a15_human(display_long)|uniprotkb:SLC6A15(gene name)|psi-mi:SLC6A15(display_short)|uniprotkb:B0AT2(gene name synonym)|uniprotkb:NTT73(gene name synonym)|uniprotkb:SBAT1(gene name synonym)|uniprotkb:Sodium- and chloride-dependent neurotransmitter transporter NTT73(gene name synonym)|uniprotkb:Sodium-coupled branched-chain amino-acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 6 member 15(gene name synonym)|uniprotkb:Transporter v7-3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001139807.1|refseq:NP_060527.2|refseq:NP_877499.1|panther:PTHR11616(orthology-group)|ensembl:ENSG00000072041.18(gene)|ensembl:ENST00000266682.10(transcript)|ensembl:ENST00000680963.1(transcript)|ensembl:ENST00000681106.1(transcript)|ensembl:ENST00000681721.1(transcript)|go:""GO:0005295""(""neutral L-amino acid:sodium symporter activity"")|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005326""(neurotransmitter transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015657""(""branched-chain amino acid:sodium symporter activity"")|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015824""(proline transport)|go:""GO:0016020""(membrane)|go:""GO:0035725""(sodium ion transmembrane transport)|interpro:IPR000175(""Sodium:neurotransmitter symporter"")|interpro:IPR002438(""Sodium:neurotransmitter symporter, orphan"")|interpro:IPR037272|interpro:IPR042934|mint:Q9H2J7|reactome:R-HSA-352230|reactome:R-HSA-442660"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:MubTClioe24j6+ldJKeHsmuzg1U9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P08240	intact:EBI-27055528	intact:EBI-726981|uniprotkb:Q9BVJ4|uniprotkb:A6NIB3|uniprotkb:B2R5Z8|uniprotkb:B4E0H3|uniprotkb:E9PJS4|ensembl:ENSP00000328023.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:srpra_human(display_long)|uniprotkb:SRPRA(gene name)|psi-mi:SRPRA(display_short)|uniprotkb:Docking protein alpha(gene name synonym)|uniprotkb:SRPR(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001171313.1|refseq:NP_003130.2|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000182934.12(gene)|ensembl:ENST00000332118.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005047""(signal recognition particle binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005785""(signal recognition particle receptor complex)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006613""(cotranslational protein targeting to membrane)|go:""GO:0006617""(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045047""(protein targeting to ER)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR007222(Signal recognition particle receptor, alpha subunit, N-terminal)|interpro:IPR011012(Longin-like)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101|mint:P08240|rcsb pdb:2FH5|rcsb pdb:2GO5|rcsb pdb:5L3Q|rcsb pdb:6Y32|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|panther:PTHR43134(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:4ag/lxPfDGSDWhpnuwQynTvCpuU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q15738	intact:EBI-27055528	intact:EBI-4280135|uniprotkb:D3DWT6|uniprotkb:O00344|ensembl:ENSP00000359297.3|ensembl:ENSP00000391854.1|ensembl:ENSP00000517980.1|ensembl:ENSP00000517982.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:nsdhl_human(display_long)|uniprotkb:NSDHL(gene name)|psi-mi:NSDHL(display_short)|uniprotkb:H105E3(gene name synonym)|uniprotkb:Protein H105e3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000147383.11(gene)|ensembl:ENSG00000292192.1(gene)|ensembl:ENST00000370274.8(transcript)|ensembl:ENST00000440023.5(transcript)|ensembl:ENST00000709998.1(transcript)|ensembl:ENST00000710000.1(transcript)|go:""GO:0000252""(""3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity"")|go:""GO:0001942""(hair follicle development)|go:""GO:0003854""(""3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity"")|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0102175""(""3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity"")|interpro:IPR002225(3-beta hydroxysteroid dehydrogenase/isomerase)|interpro:IPR036291|interpro:IPR050177|mint:Q15738|rcsb pdb:6JKG|rcsb pdb:6JKH|reactome:R-HSA-191273|refseq:NP_001123237.1|refseq:NP_057006.1|refseq:XP_011529480.1|efo:""Orphanet:139""|efo:""Orphanet:251383""|panther:PTHR10366(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Hfd2Gvro+f9sk/Wn2Dxsgh1nbfo9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q01650	intact:EBI-27055528	intact:EBI-6138761|uniprotkb:Q8IV97|uniprotkb:Q9UBN8|uniprotkb:Q9UP15|uniprotkb:Q9UQC0|ensembl:ENSP00000261622.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:lat1_human(display_long)|uniprotkb:SLC7A5(gene name)|psi-mi:SLC7A5(display_short)|uniprotkb:CD98LC(gene name synonym)|uniprotkb:LAT1(gene name synonym)|uniprotkb:MPE16(gene name synonym)|uniprotkb:4F2 light chain(gene name synonym)|uniprotkb:CD98 light chain(gene name synonym)|uniprotkb:Integral membrane protein E16(gene name synonym)|uniprotkb:L-type amino acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 7 member 5(gene name synonym)|uniprotkb:y+ system cationic amino acid transporter(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_003477.4|ensembl:ENSG00000103257.10(gene)|ensembl:ENST00000261622.5(transcript)|go:""GO:0002720""(positive regulation of cytokine production involved in immune response)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015196""(L-tryptophan transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015349""(thyroid hormone transmembrane transporter activity)|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032328""(alanine transport)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042908""(xenobiotic transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0089718""(amino acid import across plasma membrane)|go:""GO:0097421""(liver regeneration)|go:""GO:0098591""(external side of apical plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903577""(cellular response to L-arginine)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904556""(L-tryptophan transmembrane transport)|go:""GO:1905460""(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:""GO:1905534""(positive regulation of L-leucine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004760(L-type amino acid transporter)|interpro:IPR050598|mint:Q01650|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|rcsb pdb:8XPU|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-71240|panther:PTHR11785(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:GrXTCUhrHMNCnvscgx1ink2opoU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P43121	intact:EBI-27055528	intact:EBI-2339969|uniprotkb:Q6ZTR2|uniprotkb:Q6PHR3|uniprotkb:O95812|uniprotkb:Q59E86|intact:EBI-25626468|ensembl:ENSP00000264036.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:muc18_human(display_long)|uniprotkb:MCAM(gene name)|psi-mi:MCAM(display_short)|uniprotkb:MUC18(gene name synonym)|uniprotkb:Melanoma-associated antigen MUC18(gene name synonym)|uniprotkb:Melanoma cell adhesion molecule(gene name synonym)|uniprotkb:Melanoma-associated antigen A32(gene name synonym)|uniprotkb:S-endo 1 endothelial-associated antigen(gene name synonym)|uniprotkb:Cell surface glycoprotein P1H12(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_006491.2|dip:DIP-52791N|ensembl:ENSG00000076706.17(gene)|ensembl:ENST00000264036.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0003094""(glomerular filtration)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0061042""(vascular wound healing)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR051116|mint:P43121|rcsb pdb:6LYN|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR11973(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:f2hDslNdU/yJ8Ni66Wnsr1YE7Uw9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O14936	intact:EBI-27055528	intact:EBI-1215506|uniprotkb:Q5VT18|uniprotkb:Q5VT19|uniprotkb:Q66T42|uniprotkb:A6NES1|uniprotkb:O43215|uniprotkb:Q17RI4|uniprotkb:Q59HA0|uniprotkb:Q5VT16|uniprotkb:Q5VT17|uniprotkb:Q9BYH6|uniprotkb:Q9NYB2|uniprotkb:Q9NYB3|uniprotkb:B7ZKY0|ensembl:ENSP00000367405.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:cskp_human(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:777""|ensembl:ENSG00000147044.23(gene)|ensembl:ENST00000378163.7(transcript)|go:""GO:0001953""(negative regulation of cell-matrix adhesion)|go:""GO:0004385""(guanylate kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0008104""(protein localization)|go:""GO:0010839""(negative regulation of keratinocyte proliferation)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0031982""(vesicle)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0042043""(neurexin family protein binding)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046928""(regulation of neurotransmitter secretion)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0060170""(ciliary membrane)|go:""GO:0061045""(negative regulation of wound healing)|go:""GO:0070509""(calcium ion import)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0090288""(negative regulation of cellular response to growth factor stimulus)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|interpro:IPR050716|mint:O14936|rcsb pdb:1KGD|rcsb pdb:1KWA|rcsb pdb:1ZL8|rcsb pdb:3C0G|rcsb pdb:3C0H|rcsb pdb:3C0I|rcsb pdb:3MFR|rcsb pdb:3MFS|rcsb pdb:3MFT|rcsb pdb:3MFU|rcsb pdb:3TAC|rcsb pdb:6KMH|rcsb pdb:7OAI|rcsb pdb:7OAJ|rcsb pdb:7OAK|rcsb pdb:7OAL|reactome:R-HSA-212676|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-6794361|reactome:R-HSA-9609736|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001119526.1|refseq:NP_001119527.1|refseq:NP_003679.2|dip:DIP-38727N|efo:""Orphanet:163937""|efo:""Orphanet:1934""|panther:PTHR23122(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:zTaBgQexJON3EVgJq9FHjf+aSCY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q5T0W9	intact:EBI-27055528	intact:EBI-2556565|uniprotkb:Q96DQ2|uniprotkb:Q2M1P3|ensembl:ENSP00000304078.7	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:fa83b_human(display_long)|uniprotkb:C6orf143(gene name synonym)|uniprotkb:FAM83B(gene name)|psi-mi:FAM83B(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001010872.1|refseq:XP_011512696.1|refseq:XP_011512697.1|refseq:XP_006715085.1|refseq:XP_016865967.1|ensembl:ENSG00000168143.9(gene)|ensembl:ENST00000306858.8(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0036312""(phosphatidylinositol 3-kinase regulatory subunit binding)|go:""GO:0036313""(phosphatidylinositol 3-kinase catalytic subunit binding)|go:""GO:0045742""(positive regulation of epidermal growth factor receptor signaling pathway)|interpro:IPR012461(Protein of unknown function DUF1669)|interpro:IPR050944|mint:Q5T0W9|rcsb pdb:5LZK|rcsb pdb:5QHI|rcsb pdb:5QHJ|rcsb pdb:5QHK|rcsb pdb:5QHL|rcsb pdb:5QHM|rcsb pdb:5QHN|rcsb pdb:5QHO|rcsb pdb:5QHP|rcsb pdb:5QHQ|rcsb pdb:5QHR|rcsb pdb:5QHS|reactome:R-HSA-177929|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|panther:PTHR16181(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:WzQTBg74ImTqkPDdKRM0YVcGXPY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8N511	intact:EBI-27055528	intact:EBI-10265825|ensembl:ENSP00000292114.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:tm199_human(display_long)|uniprotkb:TMEM199(gene name)|psi-mi:TMEM199(display_short)|uniprotkb:C17orf32(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000244045.13(gene)|ensembl:ENST00000292114.8(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0008142""(oxysterol binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0030663""(COPI-coated vesicle membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0070072""(vacuolar proton-transporting V-type ATPase complex assembly)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR021013|mint:Q8N511|refseq:NP_689677.1|efo:""Orphanet:466703""|panther:PTHR31394(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:rk4iRiCiPucGTNfFJWXGKL01xh09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O75410	intact:EBI-27055528	intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|uniprotkb:D3DSX6|ensembl:ENSP00000321703.4|uniprotkb:B4E302	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000147526.20(gene)|ensembl:ENST00000317827.9(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0016020""(membrane)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030496""(midbody)|go:""GO:0035259""(nuclear glucocorticoid receptor binding)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0042975""(peroxisome proliferator activated receptor binding)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0051301""(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542936.1|refseq:XP_011542938.1|refseq:XP_011542939.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|efo:""Orphanet:251576""|efo:""Orphanet:251579""|panther:PTHR13924(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9NZZ3	intact:EBI-27055528	intact:EBI-751303|uniprotkb:Q5VXW2|uniprotkb:Q96AV2|uniprotkb:Q9HB68|uniprotkb:Q9NYS4|uniprotkb:Q9Y323|uniprotkb:B4DIR6|uniprotkb:B2RD95|ensembl:ENSP00000223500.7	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:chmp5_human(display_long)|uniprotkb:Chromatin-modifying protein 5(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 60(gene name synonym)|uniprotkb:SNF7 domain-containing protein 2(gene name synonym)|uniprotkb:CHMP5(gene name)|psi-mi:CHMP5(display_short)|uniprotkb:C9orf83(gene name synonym)|uniprotkb:SNF7DC2(gene name synonym)|uniprotkb:CGI-34(orf name)|uniprotkb:HSPC177(orf name)|uniprotkb:PNAS-2(orf name)|uniprotkb:PNAS-114(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_057494.3|refseq:NP_001182465.1|ensembl:ENSG00000086065.14(gene)|ensembl:ENST00000223500.9(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0000776""(kinetochore)|go:""GO:0000815""(ESCRT III complex)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0001919""(regulation of receptor recycling)|go:""GO:0005643""(nuclear pore)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005771""(multivesicular body)|go:""GO:0005828""(kinetochore microtubule)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0006914""(autophagy)|go:""GO:0006997""(nucleus organization)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015031""(protein transport)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030496""(midbody)|go:""GO:0031468""(nuclear membrane reassembly)|go:""GO:0032511""(late endosome to vacuole transport via multivesicular body sorting pathway)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0045296""(cadherin binding)|go:""GO:0046755""(viral budding)|go:""GO:0046761""(viral budding from plasma membrane)|go:""GO:0051469""(vesicle fusion with vacuole)|go:""GO:0061763""(multivesicular body-lysosome fusion)|go:""GO:0061952""(midbody abscission)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071225""(cellular response to muramyl dipeptide)|go:""GO:0071985""(multivesicular body sorting pathway)|go:""GO:0090148""(membrane fission)|go:""GO:0097352""(autophagosome maturation)|go:""GO:1901673""(regulation of mitotic spindle assembly)|go:""GO:1902774""(late endosome to lysosome transport)|go:""GO:1904903""(ESCRT III complex disassembly)|go:""GO:1904930""(amphisome membrane)|interpro:IPR005024(Snf7)|mint:Q9NZZ3|rcsb pdb:2LXM|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM2|rcsb pdb:4TXR|reactome:R-HSA-162588|reactome:R-HSA-917729|dip:DIP-50420N|panther:PTHR22761(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:VqeFh9Sg3XIfJuZBF59GgMgY53c9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9H2H9	intact:EBI-27055528	intact:EBI-9978441|uniprotkb:Q8NC61|uniprotkb:Q8NCF8|uniprotkb:Q96JX2|uniprotkb:Q9H2Q2|ensembl:ENSP00000381634.4|ensembl:ENSP00000398142.1|ensembl:ENSP00000447853.1|ensembl:ENSP00000449607.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:s38a1_human(display_long)|uniprotkb:SLC38A1(gene name)|psi-mi:SLC38A1(display_short)|uniprotkb:ATA1(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:SAT1(gene name synonym)|uniprotkb:SNAT1(gene name synonym)|uniprotkb:Amino acid transporter A1(gene name synonym)|uniprotkb:N-system amino acid transporter 2(gene name synonym)|uniprotkb:Solute carrier family 38 member 1(gene name synonym)|uniprotkb:System A amino acid transporter 1(gene name synonym)|uniprotkb:System N amino acid transporter 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001070952.1|refseq:NP_001265316.1|refseq:NP_001265317.1|refseq:NP_001265318.1|refseq:NP_109599.3|ensembl:ENSG00000111371.16(gene)|ensembl:ENST00000398637.10(transcript)|ensembl:ENST00000439706.5(transcript)|ensembl:ENST00000546893.5(transcript)|ensembl:ENST00000549049.5(transcript)|go:""GO:0001504""(neurotransmitter uptake)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005283""(""amino acid:sodium symporter activity"")|go:""GO:0005295""(""neutral L-amino acid:sodium symporter activity"")|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0006865""(amino acid transport)|go:""GO:0006868""(glutamine transport)|go:""GO:0007565""(female pregnancy)|go:""GO:0009449""(gamma-aminobutyric acid biosynthetic process)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015186""(L-glutamine transmembrane transporter activity)|go:""GO:0015375""(""glycine:sodium symporter activity"")|go:""GO:0015655""(""alanine:sodium symporter activity"")|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0032228""(regulation of synaptic transmission, GABAergic)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043090""(amino acid import)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098591""(external side of apical plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901036""(positive regulation of L-glutamine import across plasma membrane)|go:""GO:1902475""(L-alpha-amino acid transmembrane transport)|interpro:IPR013057(Amino acid transporter, transmembrane)|mint:Q9H2H9|reactome:R-HSA-210455|reactome:R-HSA-352230|panther:PTHR22950(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:bywv401DbQBHRZvcPc8o8mp8nfE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q13586	intact:EBI-27055528	intact:EBI-448878|uniprotkb:Q8N382|uniprotkb:E9PQJ4|ensembl:ENSP00000300737.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR15136(orthology-group)|efo:""Orphanet:2593""|efo:""Orphanet:317430""|efo:""Orphanet:3204""|dip:DIP-31121N|ensembl:ENSG00000167323.13(gene)|ensembl:ENST00000300737.8(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0002115""(store-operated calcium entry)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005513""(detection of calcium ion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0032237""(activation of store-operated calcium channel activity)|go:""GO:0032541""(cortical endoplasmic reticulum)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045762""(positive regulation of adenylate cyclase activity)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0070166""(enamel mineralization)|go:""GO:2001256""(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|mint:Q13586|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|refseq:NP_003147.2"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y5M8	intact:EBI-27055528	intact:EBI-355393|uniprotkb:Q8N2D8|uniprotkb:Q6P595|ensembl:ENSP00000418401.1|ensembl:ENSP00000503923.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:srprb_human(display_long)|uniprotkb:SRPRB(gene name)|psi-mi:SRPRB(display_short)|uniprotkb:PSEC0230(orf name)|uniprotkb:Protein APMCF1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_067026.3|ensembl:ENSG00000144867.13(gene)|ensembl:ENST00000466490.7(transcript)|ensembl:ENST00000678299.1(transcript)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005785""(signal recognition particle receptor complex)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0006617""(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:""GO:0016020""(membrane)|go:""GO:0045047""(protein targeting to ER)|interpro:IPR019009|interpro:IPR024156|interpro:IPR027417|mint:Q9Y5M8|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|dip:DIP-50218N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:pHUdnCvOhMRYIJg//OJ+SlCard49606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9HCM4	intact:EBI-27055528	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|ensembl:ENSG00000115109.14(gene)|ensembl:ENST00000263713.10(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001839""(neural plate morphogenesis)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0003383""(apical constriction)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006931""(substrate-dependent cell migration, cell attachment to substrate)|go:""GO:0007398""(ectoderm development)|go:""GO:0007492""(endoderm development)|go:""GO:0007509""(mesoderm migration involved in gastrulation)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009826""(unidimensional cell growth)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032525""(somite rostral/caudal axis specification)|go:""GO:0032587""(ruffle membrane)|go:""GO:0048319""(axial mesoderm morphogenesis)|go:""GO:0048339""(paraxial mesoderm development)|go:""GO:0048617""(embryonic foregut morphogenesis)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0070201""(regulation of establishment of protein localization)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|mint:Q9HCM4|reactome:R-HSA-6794361|refseq:NP_001317239.1|panther:PTHR23280(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q96AG4	intact:EBI-27055528	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|uniprotkb:B2RE83|ensembl:ENSP00000225972.7	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_060979.2|ensembl:ENSG00000108829.10(gene)|ensembl:ENST00000225972.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045296""(cadherin binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050216|mint:Q96AG4|panther:PTHR45752(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q7L576	intact:EBI-27055528	intact:EBI-1048143|uniprotkb:Q14467|uniprotkb:Q5IED0|uniprotkb:Q6ZSX1|uniprotkb:Q9BSD9|uniprotkb:Q9BVC7|uniprotkb:A8K6D9|ensembl:ENSP00000478779.1|ensembl:ENSP00000481038.1|ensembl:ENSP00000499947.1|ensembl:ENSP00000500331.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:cyfp1_human(display_long)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)|uniprotkb:p140sra-1(gene name synonym)|uniprotkb:CYFIP1(gene name)|psi-mi:CYFIP1(display_short)|uniprotkb:KIAA0068(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001028200.1|refseq:NP_055423.1|refseq:NP_001274739.1|ensembl:ENSG00000273749.5(gene)|ensembl:ENSG00000288461.1(gene)|ensembl:ENST00000610365.4(transcript)|ensembl:ENST00000617928.5(transcript)|ensembl:ENST00000671714.1(transcript)|ensembl:ENST00000672091.1(transcript)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001726""(ruffle)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006417""(regulation of translation)|go:""GO:0007411""(axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0030027""(lamellipodium)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030371""(translation repressor activity)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0031209""(SCAR complex)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031529""(ruffle organization)|go:""GO:0031641""(regulation of myelination)|go:""GO:0032433""(filopodium tip)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043195""(terminal bouton)|go:""GO:0043197""(dendritic spine)|go:""GO:0044294""(dendritic growth cone)|go:""GO:0044295""(axonal growth cone)|go:""GO:0045202""(synapse)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048675""(axon extension)|go:""GO:0050890""(cognition)|go:""GO:0051015""(actin filament binding)|go:""GO:0051388""(positive regulation of neurotrophin TRK receptor signaling pathway)|go:""GO:0051602""(response to electrical stimulus)|go:""GO:0060076""(excitatory synapse)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090724""(central region of growth cone)|go:""GO:0090725""(peripheral region of growth cone)|go:""GO:0097484""(dendrite extension)|go:""GO:0099563""(modification of synaptic structure)|go:""GO:0099578""(regulation of translation at postsynapse, modulating synaptic transmission)|go:""GO:1900006""(positive regulation of dendrite development)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1903422""(negative regulation of synaptic vesicle recycling)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:2000601""(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7L576|rcsb pdb:3P8C|rcsb pdb:4N78|rcsb pdb:7USC|rcsb pdb:7USD|rcsb pdb:7USE|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001311049.1|refseq:NP_001311052.1|dip:DIP-38873N|panther:PTHR12195(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:cEF+RA9JRXz8Mbsl/s89Up2ONRc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9HDC5	intact:EBI-27055528	intact:EBI-465137|uniprotkb:B2RTZ0|ensembl:ENSP00000344488.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_065698.1|refseq:XP_005251331.1|refseq:XP_005251332.1|refseq:NP_001304759.1|panther:PTHR23085(orthology-group)|ensembl:ENSG00000104369.5(gene)|ensembl:ENST00000342232.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007517""(muscle organ development)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0014701""(junctional sarcoplasmic reticulum membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0030018""(Z disc)|go:""GO:0030314""(junctional membrane complex)|go:""GO:0060314""(regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0060402""(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|rcsb pdb:7RW4"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P04843	intact:EBI-27055528	intact:EBI-355963|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0|ensembl:ENSP00000296255.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:402020""|ensembl:ENSG00000163902.12(gene)|ensembl:ENST00000296255.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0042470""(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_002941.1|dip:DIP-38152N|panther:PTHR21049(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q86XL3	intact:EBI-27055528	intact:EBI-1773621|uniprotkb:O75176|uniprotkb:Q6P6A5|uniprotkb:Q96DH4|uniprotkb:Q8TAZ9|uniprotkb:A8KAG3|uniprotkb:B3KN97|uniprotkb:B3KSF8|ensembl:ENSP00000350686.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ankl2_human(display_long)|uniprotkb:ANKLE2(gene name)|psi-mi:ANKLE2(display_short)|uniprotkb:KIAA0692(gene name synonym)|uniprotkb:LEM domain-containing protein 4(gene name synonym)|uniprotkb:LEM4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:2512""|ensembl:ENSG00000176915.15(gene)|ensembl:ENST00000357997.10(transcript)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007084""(mitotic nuclear membrane reassembly)|go:""GO:0007417""(central nervous system development)|go:""GO:0016020""(membrane)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0042326""(negative regulation of phosphorylation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0050790""(regulation of catalytic activity)|go:""GO:0051301""(cell division)|go:""GO:0051721""(protein phosphatase 2A binding)|interpro:IPR002110(Ankyrin)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR011320(Ribonuclease HI, N-terminal)|interpro:IPR035006|interpro:IPR036770|interpro:IPR037056|mint:Q86XL3|reactome:R-HSA-2995383|reactome:R-HSA-9013404|reactome:R-HSA-9013408|refseq:NP_055929.1|refseq:XP_011533089.1|refseq:XP_011533090.1|panther:PTHR12349(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Gaa+XAC6xNVobxZhMlzCHvVDFgk9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P19367	intact:EBI-27055528	intact:EBI-713162|ensembl:ENSP00000352398.6|uniprotkb:Q5VTC3|uniprotkb:Q96HC8|uniprotkb:Q9NNZ4|uniprotkb:O43443|uniprotkb:O43444|uniprotkb:O75574|uniprotkb:Q9NNZ5|uniprotkb:E9PCK0	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:hxk1_human(display_long)|uniprotkb:Hexokinase type I(gene name synonym)|uniprotkb:Brain form hexokinase(gene name synonym)|uniprotkb:HK1(gene name)|psi-mi:HK1(display_short)|uniprotkb:Hexokinase-A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000156515.25(gene)|ensembl:ENST00000359426.7(transcript)|go:""GO:0001678""(intracellular glucose homeostasis)|go:""GO:0002720""(positive regulation of cytokine production involved in immune response)|go:""GO:0004340""(glucokinase activity)|go:""GO:0004396""(hexokinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005536""(D-glucose binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006002""(fructose 6-phosphate metabolic process)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006013""(mannose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0008865""(fructokinase activity)|go:""GO:0009298""(GDP-mannose biosynthetic process)|go:""GO:0019158""(mannokinase activity)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0042834""(peptidoglycan binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0046835""(carbohydrate phosphorylation)|go:""GO:0047931""(glucosamine kinase activity)|go:""GO:0051156""(glucose 6-phosphate metabolic process)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0061728""(GDP-mannose biosynthetic process from mannose)|go:""GO:0072655""(establishment of protein localization to mitochondrion)|go:""GO:0072656""(maintenance of protein location in mitochondrion)|go:""GO:0141199""(obsolete GDP-mannose biosynthetic process from glucose)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:P19367|rcsb pdb:1CZA|rcsb pdb:1DGK|rcsb pdb:1HKB|rcsb pdb:1HKC|rcsb pdb:1QHA|rcsb pdb:4F9O|rcsb pdb:4FOE|rcsb pdb:4FOI|rcsb pdb:4FPA|rcsb pdb:4FPB|reactome:R-HSA-446205|reactome:R-HSA-5619056|reactome:R-HSA-70171|refseq:NP_000179.2|refseq:NP_001309293.1|refseq:NP_277031.1|refseq:NP_277032.1|refseq:NP_277033.1|refseq:NP_277035.2|refseq:XP_011538034.1|efo:""Orphanet:90031""|efo:""Orphanet:99953""|dip:DIP-56245N|ensembl:ENST00000298649.8|ensembl:ENSP00000298649.3|ensembl:ENSP00000352398.6|ensembl:ENST00000436817.6|ensembl:ENSP00000415949.2|ensembl:ENST00000643399.2|ensembl:ENSP00000494664.1|panther:PTHR19443(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:cvNEGlnCikx3E17kNYTSI39EUfU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q12923	intact:EBI-27055528	intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENSG00000163629.13(gene)|ensembl:ENST00000411767.7(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|interpro:IPR000299(Band 4.1, N-terminal)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0036312""(phosphatidylinositol 3-kinase regulatory subunit binding)|go:""GO:0044297""(cell body)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097237""(cellular response to toxic substance)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1904890""(negative regulation of excitatory synapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|interpro:IPR052074|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|rcsb pdb:7QCX|rcsb pdb:7QCY|rcsb pdb:7XTY|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-40449N|panther:PTHR46900(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P04439	intact:EBI-27055528	intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155|ensembl:ENSP00000366005.5|ensembl:ENSP00000379873.1|ensembl:ENSP00000516612.1|ensembl:ENSP00000516614.1|ensembl:ENSP00000516616.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:179""|ensembl:ENSG00000206503.15(gene)|ensembl:ENST00000376809.10(transcript)|ensembl:ENST00000396634.5(transcript)|ensembl:ENST00000706901.1(transcript)|ensembl:ENST00000706903.1(transcript)|ensembl:ENST00000706905.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002419""(T cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002485""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0003723""(RNA binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0062061""(TAP complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2000568""(positive regulation of memory T cell activation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WJ5|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7MLE|rcsb pdb:7PHR|rcsb pdb:7QPD|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7STF|rcsb pdb:7UC5|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|rcsb pdb:8DVG|rcsb pdb:8RYM|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_001229687.1|refseq:NP_002107.3|ensembl:ENSP00000366005.5|ensembl:ENSP00000379873.1|ensembl:ENSP00000516612.1|ensembl:ENSP00000516614.1|ensembl:ENSP00000516616.1|panther:PTHR16675(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y385	intact:EBI-27055528	intact:EBI-988826|uniprotkb:Q5W0N4|uniprotkb:Q9BZ32|uniprotkb:Q9NQL3|uniprotkb:Q9NY66|uniprotkb:Q9P011|uniprotkb:Q9P0S0|uniprotkb:Q9UF10|uniprotkb:A8K3F9|uniprotkb:Q53F25|ensembl:ENSP00000451261.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ub2j1_human(display_long)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:Yeast ubiquitin-conjugating enzyme UBC6 homolog E(gene name synonym)|uniprotkb:UBE2J1(gene name)|psi-mi:UBE2J1(display_short)|uniprotkb:NCUBE1(gene name synonym)|uniprotkb:CGI-76(orf name)|uniprotkb:HSPC153(orf name)|uniprotkb:HSPC205(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme J1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_057105.2|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR050113|mint:Q9Y385|reactome:R-HSA-983168|ensembl:ENSG00000198833.7(gene)|ensembl:ENST00000435041.3(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007286""(spermatid development)|go:""GO:0010935""(regulation of macrophage cytokine production)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0036503""(ERAD pathway)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:1904153""(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|dip:DIP-45598N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:nc3+V3Qxy1ZDhTWgTPLakJukxPM9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P48729	intact:EBI-27055528	intact:EBI-1383726|uniprotkb:Q96HD2|uniprotkb:Q5U046|uniprotkb:Q5U047|uniprotkb:Q6FGA2|uniprotkb:Q4JJA0|uniprotkb:Q9UDK3|uniprotkb:D3DQG0|uniprotkb:D3DQG1|uniprotkb:Q71TU5|intact:EBI-11048253|ensembl:ENSP00000367074.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:kc1a_human(display_long)|uniprotkb:CSNK1A1(gene name)|psi-mi:CSNK1A1(display_short)|uniprotkb:CK1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001020276.1|refseq:NP_001883.4|refseq:NP_001258670.1|refseq:NP_001258671.1|ensembl:ENSG00000113712.19(gene)|ensembl:ENST00000377843.8(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007030""(Golgi organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016607""(nuclear speck)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019082""(viral protein processing)|go:""GO:0030877""(beta-catenin destruction complex)|go:""GO:0031670""(cellular response to nutrient)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0051301""(cell division)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050235|mint:P48729|rcsb pdb:5FQD|rcsb pdb:6GZD|rcsb pdb:7WTT|rcsb pdb:8G66|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5635838|reactome:R-HSA-9694631|dip:DIP-40367N|panther:PTHR11909(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q7Z434	intact:EBI-27055528	intact:EBI-995373|uniprotkb:Q3I0Y2|uniprotkb:Q5T7I6|uniprotkb:Q86VY7|uniprotkb:Q9H1H3|uniprotkb:Q9H4Y1|uniprotkb:Q9H8D3|uniprotkb:Q9ULE9|uniprotkb:Q2HWT5|uniprotkb:A8K6X0|uniprotkb:F5H6C8|uniprotkb:B2BD33|uniprotkb:B2BD34|uniprotkb:M1P2Z0|ensembl:ENSP00000401980.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mavs_human(display_long)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001193420.1|refseq:NP_065797.2|dip:DIP-35445N|ensembl:ENSG00000088888.18(gene)|ensembl:ENST00000428216.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0002230""(positive regulation of defense response to virus by host)|go:""GO:0002735""(positive regulation of myeloid dendritic cell cytokine production)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0039552""(RIG-I binding)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050700""(CARD domain binding)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060760""(positive regulation of response to cytokine stimulus)|go:""GO:0070585""(protein localization to mitochondrion)|go:""GO:0071360""(cellular response to exogenous dsRNA)|go:""GO:0071651""(""positive regulation of chemokine (C-C motif) ligand 5 production"")|go:""GO:0071660""(positive regulation of IP-10 production)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900063""(regulation of peroxisome organization)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR011029(DEATH-like)|interpro:IPR031964|interpro:IPR042144|interpro:IPR052787|mint:Q7Z434|rcsb pdb:2MS7|rcsb pdb:2MS8|rcsb pdb:2VGQ|rcsb pdb:3J6C|rcsb pdb:3J6J|rcsb pdb:3RC5|rcsb pdb:4P4H|rcsb pdb:4Z8M|rcsb pdb:5JEK|rcsb pdb:7DNI|rcsb pdb:8WKW|reactome:R-HSA-168928|reactome:R-HSA-5689896|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|reactome:R-HSA-9692916|reactome:R-HSA-9705671|reactome:R-HSA-9833109|reactome:R-HSA-9833482|panther:PTHR21446(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P07947	intact:EBI-27055528	intact:EBI-515331|uniprotkb:A6NLB3|uniprotkb:D3DUH1|ensembl:ENSP00000324740.4|ensembl:ENSP00000462468.1|intact:EBI-28995389	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:yes_human(display_long)|uniprotkb:p61-Yes(gene name synonym)|uniprotkb:Proto-oncogene c-Yes(gene name synonym)|uniprotkb:YES1(gene name)|psi-mi:YES1(display_short)|uniprotkb:YES(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_016881449.1|refseq:NP_005424.1|ensembl:ENSG00000176105.14(gene)|ensembl:ENST00000314574.5(transcript)|ensembl:ENST00000584307.5(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0010827""(regulation of D-glucose transmembrane transport)|go:""GO:0019899""(enzyme binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031295""(T cell costimulation)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036211""(protein modification process)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0043114""(regulation of vascular permeability)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050900""(leukocyte migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0140801""(histone H2AXY142 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035751|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P07947|rcsb pdb:2HDA|reactome:R-HSA-1227986|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2682334|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-8940973|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9680350|dip:DIP-33849N|panther:PTHR24418(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Wo+NWxPVSmF8W6ZHQmTPpg3YuY09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q96HN2	intact:EBI-27055528	intact:EBI-1056923|uniprotkb:O94917|uniprotkb:B4DIZ5|uniprotkb:D9N155|ensembl:ENSP00000315931.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	"psi-mi:sahh3_human(display_long)|uniprotkb:AHCYL2(gene name)|psi-mi:AHCYL2(display_short)|uniprotkb:KIAA0828(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 3(gene name synonym)|uniprotkb:S-adenosylhomocysteine hydrolase-like protein 2(gene name synonym)|uniprotkb:""IP(3)Rs binding protein released with IP(3) 2""(gene name synonym)|uniprotkb:Long-IRBIT(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001124192.1|refseq:NP_001124194.2|refseq:NP_001124195.1|refseq:NP_056143.1|ensembl:ENSG00000158467.17(gene)|ensembl:ENST00000325006.8(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0016787""(hydrolase activity)|go:""GO:0033353""(S-adenosylmethionine cycle)|go:""GO:0043005""(neuron projection)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:Q96HN2|rcsb pdb:3GVP|reactome:R-HSA-425381|panther:PTHR23420(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:OOrDmlSeGOWqnAhYQcNa4tF5pk09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q96S66	intact:EBI-27055528	intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|intact:EBI-40264131|ensembl:ENSP00000349456.2|ensembl:ENSP00000358986.3|ensembl:ENSP00000502251.1|ensembl:ENSP00000502457.1|ensembl:ENSP00000502648.1|ensembl:ENSP00000502836.1|ensembl:ENSP00000508473.1|ensembl:ENSP00000508563.1|ensembl:ENSP00000508607.1|ensembl:ENSP00000508816.1|ensembl:ENSP00000508884.1|ensembl:ENSP00000508952.1|ensembl:ENSP00000508982.1|ensembl:ENSP00000509013.1|ensembl:ENSP00000509036.1|ensembl:ENSP00000509218.1|ensembl:ENSP00000509330.1|ensembl:ENSP00000509420.1|ensembl:ENSP00000509451.1|ensembl:ENSP00000509533.1|ensembl:ENSP00000509544.1|ensembl:ENSP00000509584.1|ensembl:ENSP00000509782.1|ensembl:ENSP00000509936.1|ensembl:ENSP00000509960.1|ensembl:ENSP00000509990.1|ensembl:ENSP00000510067.1|ensembl:ENSP00000510137.1|ensembl:ENSP00000510142.1|ensembl:ENSP00000510291.1|ensembl:ENSP00000510352.1|ensembl:ENSP00000510582.1|ensembl:ENSP00000510602.1|ensembl:ENSP00000510666.1|ensembl:ENSP00000510675.1|ensembl:ENSP00000510715.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:clcc1_human(display_long)|uniprotkb:ER anion channel 1(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein(gene name synonym)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940.17(gene)|ensembl:ENST00000356970.6(transcript)|ensembl:ENST00000369969.7(transcript)|ensembl:ENST00000674849.1(transcript)|ensembl:ENST00000675508.1(transcript)|ensembl:ENST00000675654.1(transcript)|ensembl:ENST00000675956.1(transcript)|ensembl:ENST00000685014.1(transcript)|ensembl:ENST00000685104.1(transcript)|ensembl:ENST00000685497.1(transcript)|ensembl:ENST00000685540.1(transcript)|ensembl:ENST00000686078.1(transcript)|ensembl:ENST00000686776.1(transcript)|ensembl:ENST00000686821.1(transcript)|ensembl:ENST00000687328.1(transcript)|ensembl:ENST00000687449.1(transcript)|ensembl:ENST00000687591.1(transcript)|ensembl:ENST00000687865.1(transcript)|ensembl:ENST00000688285.1(transcript)|ensembl:ENST00000688778.1(transcript)|ensembl:ENST00000689189.1(transcript)|ensembl:ENST00000689351.1(transcript)|ensembl:ENST00000689359.1(transcript)|ensembl:ENST00000689991.1(transcript)|ensembl:ENST00000690509.1(transcript)|ensembl:ENST00000690756.1(transcript)|ensembl:ENST00000690781.1(transcript)|ensembl:ENST00000690874.1(transcript)|ensembl:ENST00000691513.1(transcript)|ensembl:ENST00000691556.1(transcript)|ensembl:ENST00000691731.1(transcript)|ensembl:ENST00000692404.1(transcript)|ensembl:ENST00000692511.1(transcript)|ensembl:ENST00000692795.1(transcript)|ensembl:ENST00000693089.1(transcript)|ensembl:ENST00000693336.1(transcript)|ensembl:ENST00000693673.1(transcript)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0034707""(chloride channel complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|interpro:IPR009231(Mid-1-related chloride channel)|mint:Q96S66|panther:PTHR34093(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q14318	intact:EBI-27055528	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|uniprotkb:C8C9T5|ensembl:ENSP00000222308.4|ensembl:ENSP00000472302.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_036313.3|refseq:XP_011526165.1|refseq:NP_001295302.1|ensembl:ENSG00000105701.16(gene)|ensembl:ENST00000222308.8(transcript)|ensembl:ENST00000596558.6(transcript)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005740""(mitochondrial envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006915""(apoptotic process)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0021904""(dorsal/ventral neural tube patterning)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0043010""(camera-type eye development)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0048665""(neuron fate specification)|go:""GO:0070585""(protein localization to mitochondrion)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|go:""GO:1901524""(regulation of mitophagy)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR046357|interpro:IPR050754|mint:Q14318|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|dip:DIP-42200N|panther:PTHR46512(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q92738	intact:EBI-27055528	intact:EBI-8684930|uniprotkb:Q15400|uniprotkb:Q7L0K9|uniprotkb:A8KA79|intact:MINT-1518588|uniprotkb:Q5VV10|ensembl:ENSP00000476462.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:us6nl_human(display_long)|uniprotkb:USP6NL(gene name)|psi-mi:USP6NL(display_short)|uniprotkb:KIAA0019(gene name synonym)|uniprotkb:Related to the N-terminus of tre(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_055503.1|refseq:NP_001073960.1|ensembl:ENSG00000148429.15(gene)|ensembl:ENST00000609104.6(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007030""(Golgi organization)|go:""GO:0019068""(virion assembly)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0035526""(retrograde transport, plasma membrane to Golgi)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|interpro:IPR050302|mint:Q92738|reactome:R-HSA-6811440|panther:PTHR22957(orthology-group)"	-	-	comment:mint|function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:R6Zcg3PPIbqU3k8dozBFa3POnzE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O95490	intact:EBI-27055528	intact:EBI-2865302|uniprotkb:Q9UKY5|uniprotkb:B1ALT9|uniprotkb:B1ALU0|uniprotkb:Q9UKY6|uniprotkb:B1ALT8|uniprotkb:O94882|uniprotkb:Q5VX76|uniprotkb:A5XEI2|uniprotkb:B1ALU2|uniprotkb:B1ALU4|uniprotkb:B1ALU5|uniprotkb:B1ALU6|ensembl:ENSP00000359752.3|ensembl:ENSP00000359763.1|intact:EBI-28986872	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:agrl2_human(display_long)|uniprotkb:ADGRL2(gene name)|psi-mi:ADGRL2(display_short)|uniprotkb:Calcium-independent alpha-latrotoxin receptor 2(gene name synonym)|uniprotkb:KIAA0786(gene name synonym)|uniprotkb:LEC1(gene name synonym)|uniprotkb:LPHH1(gene name synonym)|uniprotkb:LPHN2(gene name synonym)|uniprotkb:Latrophilin homolog 1(gene name synonym)|uniprotkb:Latrophilin-2(gene name synonym)|uniprotkb:Lectomedin-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_036434.1|refseq:XP_005270723.1|refseq:NP_001284633.1|refseq:NP_001284634.1|refseq:NP_001284635.1|refseq:NP_001317574.1|refseq:XP_016856276.1|ensembl:ENSG00000117114.21(gene)|ensembl:ENST00000370717.6(transcript)|ensembl:ENST00000370728.5(transcript)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016524""(latrotoxin receptor activity)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR017981|interpro:IPR017983|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159|interpro:IPR046338|mint:O95490|panther:PTHR12011(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:WkTs1zEQmAT82KxUL2+V7KG74UQ9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q13613	intact:EBI-27055528	intact:EBI-11320553|ensembl:ENSP00000359417.3|uniprotkb:A0A024RC07|uniprotkb:Q9UEM0|uniprotkb:Q9UBX6|uniprotkb:Q9UQD5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mtmr1_human(display_long)|uniprotkb:MTMR1(gene name)|psi-mi:MTMR1(display_short)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Myotubularin-related protein 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000063601.17(gene)|ensembl:ENST00000370390.7(transcript)|go:""GO:0004438""(phosphatidylinositol-3-phosphate phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|go:""GO:0052629""(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:""GO:0060304""(regulation of phosphatidylinositol dephosphorylation)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004182(GRAM)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR030564|interpro:IPR030587|interpro:IPR037857|mint:Q13613|rcsb pdb:5C16|reactome:R-HSA-1660499|reactome:R-HSA-9035034|refseq:NP_003819.1|refseq:XP_006724918.1|panther:PTHR10807(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:IVRpk4aChsv/2Kxc5LYA+yOU6Vw9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q96Q42	intact:EBI-27055528	intact:EBI-1044902|uniprotkb:Q8N1E0|uniprotkb:Q96PC4|uniprotkb:Q96Q41|uniprotkb:Q9H973|uniprotkb:Q9HCK9|uniprotkb:Q53TT1|uniprotkb:Q53TV2|ensembl:ENSP00000264276.6|ensembl:ENSP00000505043.1|ensembl:ENSP00000505092.1|ensembl:ENSP00000505187.1|ensembl:ENSP00000505218.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:als2_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein(gene name synonym)|uniprotkb:ALS2(gene name)|psi-mi:ALS2(display_short)|uniprotkb:KIAA1563(gene name synonym)|uniprotkb:ALS2CR6(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:247604""|efo:""Orphanet:293168""|efo:""Orphanet:300605""|ensembl:ENSG00000003393.16(gene)|ensembl:ENST00000264276.11(transcript)|ensembl:ENST00000679435.1(transcript)|ensembl:ENST00000679516.1(transcript)|ensembl:ENST00000680163.1(transcript)|ensembl:ENST00000680861.1(transcript)|go:""GO:0001662""(behavioral fear response)|go:""GO:0001726""(ruffle)|go:""GO:0001881""(receptor recycling)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007032""(endosome organization)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008104""(protein localization)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016197""(endosomal transport)|go:""GO:0030027""(lamellipodium)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0035249""(synaptic transmission, glutamatergic)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043197""(dendritic spine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051036""(regulation of endosome size)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR003409(MORN motif)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037191|interpro:IPR051984|mint:Q96Q42|reactome:R-HSA-8876198|reactome:R-HSA-9013149|refseq:NP_001129217.1|refseq:NP_065970.2|refseq:XP_006712717.1|panther:PTHR46089(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:/CbIkwBlU9LPad9mVvtQAgsHwmk9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q03001	intact:EBI-27055528	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783|uniprotkb:E7ERU0	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:314381""|efo:""Orphanet:412181""|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005882""(intermediate filament)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008017""(microtubule binding)|go:""GO:0008090""(retrograde axonal transport)|go:""GO:0009611""(response to wounding)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0030018""(Z disc)|go:""GO:0030056""(hemidesmosome)|go:""GO:0030424""(axon)|go:""GO:0031252""(cell leading edge)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031581""(hemidesmosome assembly)|go:""GO:0031673""(H zone)|go:""GO:0035371""(microtubule plus-end)|go:""GO:0042060""(wound healing)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0048870""(cell motility)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|interpro:IPR049538|mint:Q03001|rcsb pdb:3GJO|rcsb pdb:7OLG|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_001714.1|refseq:NP_056363.2|refseq:NP_899236.1|refseq:XP_016866713.1|dip:DIP-33131N|panther:PTHR23169(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q13480	intact:EBI-27055528	intact:EBI-517684|uniprotkb:Q4W5G2|uniprotkb:Q6P1W2|uniprotkb:A8K152|ensembl:ENSP00000262994.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:gab1_human(display_long)|uniprotkb:Growth factor receptor bound protein 2-associated protein 1(gene name synonym)|uniprotkb:GRB2-associated binder 1(gene name synonym)|uniprotkb:GAB1(gene name)|psi-mi:GAB1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_002030.2|refseq:NP_997006.1|panther:PTHR45960(orthology-group)|ensembl:ENSG00000109458.10(gene)|ensembl:ENST00000262994.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005911""(cell-cell junction)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035728""(response to hepatocyte growth factor)|go:""GO:0035767""(endothelial cell chemotaxis)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0045766""(positive regulation of angiogenesis)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR046355|mint:Q13480|rcsb pdb:4QSY|reactome:R-HSA-109704|reactome:R-HSA-1236382|reactome:R-HSA-1257604|reactome:R-HSA-180292|reactome:R-HSA-1963642|reactome:R-HSA-2219530|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853659|reactome:R-HSA-8865999|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-9664565|reactome:R-HSA-9665348"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:AIK39gZJknpy3vQK/GraIpBbgzU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9H3Q1	intact:EBI-27055528	intact:EBI-744665|uniprotkb:O95828|uniprotkb:Q96FT3|uniprotkb:B3KUS7|ensembl:ENSP00000338258.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:borg4_human(display_long)|uniprotkb:Binder of Rho GTPases 4(gene name synonym)|uniprotkb:CDC42EP4(gene name)|psi-mi:CDC42EP4(display_short)|uniprotkb:BORG4(gene name synonym)|uniprotkb:CEP4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_036253.2|refseq:XP_005257239.1|ensembl:ENSG00000179604.10(gene)|ensembl:ENST00000335793.4(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0012505""(endomembrane system)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0071346""(cellular response to type II interferon)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR029273|interpro:IPR051296|mint:Q9H3Q1|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|panther:PTHR15344(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:HC1q85v0D6AOKZ82FKaBdAEv1mE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O95248	intact:EBI-27055528	intact:EBI-2322878|uniprotkb:A6PVG9|uniprotkb:O60228|uniprotkb:Q5JXD8|uniprotkb:Q5PPM2|uniprotkb:Q96GR9|uniprotkb:Q9UGB8|uniprotkb:A0A024R4Z9|uniprotkb:G5E933|ensembl:ENSP00000510414.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mtmr5_human(display_long)|uniprotkb:SBF1(gene name)|psi-mi:SBF1(display_short)|uniprotkb:MTMR5(gene name synonym)|uniprotkb:SET-binding factor 1(gene name synonym)|uniprotkb:Inactive phosphatidylinositol 3-phosphatase 5(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000100241.22(gene)|ensembl:ENST00000689129.1(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007286""(spermatid development)|go:""GO:0008138""(protein tyrosine/serine/threonine phosphatase activity)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0043005""(neuron projection)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR001194(DENN)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004182(GRAM)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022096|interpro:IPR029021|interpro:IPR030564|interpro:IPR037516|interpro:IPR043153|mint:O95248|reactome:R-HSA-1483248|reactome:R-HSA-8876198|refseq:NP_002963.2|efo:""Orphanet:363981""|panther:PTHR10807(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:VTuIGKsw1QF3CSAFzIFnufmVGU09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q5SQN1	intact:EBI-27055528	intact:EBI-10244848|uniprotkb:Q8TB31|uniprotkb:Q9BT10|uniprotkb:Q5TBZ3|uniprotkb:Q96FE1|uniprotkb:Q8N558|uniprotkb:Q8WV46|uniprotkb:Q96CQ3|uniprotkb:Q8TCW8|uniprotkb:Q96NU3|uniprotkb:Q5HYB5|uniprotkb:Q96I66|uniprotkb:Q9BVB2|uniprotkb:B6EDE0	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:snp47_human(display_long)|uniprotkb:SNAP47(gene name)|psi-mi:SNAP47(display_short)|uniprotkb:C1orf142(gene name synonym)|uniprotkb:Epididymis luminal protein 170(gene name synonym)|uniprotkb:HEL170(gene name synonym)|uniprotkb:SVAP1(gene name synonym)|uniprotkb:Synaptosomal-associated 47 kDa protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0012505""(endomembrane system)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0019905""(syntaxin binding)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0098793""(presynapse)|refseq:NP_001310864.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR000727(Target SNARE coiled-coil region)|refseq:NP_444280.2|refseq:XP_016855720.1|refseq:XP_016855721.1|panther:PTHR19305(orthology-group)|interpro:IPR004182(GRAM)|mint:Q5SQN1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:hKGKMfU5GPf/qU+vuwByphqX3NA9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q5EBL8	intact:EBI-27055528	intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666.4|ensembl:ENSP00000363578.1|ensembl:ENSP00000512017.1|ensembl:ENSP00000512018.1|ensembl:ENSP00000512019.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509.12(gene)|ensembl:ENST00000239666.9(transcript)|ensembl:ENST00000374454.1(transcript)|ensembl:ENST00000473667.6(transcript)|ensembl:ENST00000486461.2(transcript)|ensembl:ENST00000695560.1(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0046930""(pore complex)|go:""GO:0046931""(pore complex assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051109|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837|panther:PTHR14063(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9HAD4	intact:EBI-27055528	intact:EBI-2819137|uniprotkb:Q8NDA7|uniprotkb:Q9NV62|uniprotkb:Q8IWG3|uniprotkb:Q7Z792|uniprotkb:Q8IXA9|uniprotkb:B4DT55|ensembl:ENSP00000296679.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:wdr41_human(display_long)|uniprotkb:WDR41(gene name)|psi-mi:WDR41(display_short)|uniprotkb:MSTP048(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_060738.2|ensembl:ENSG00000164253.14(gene)|ensembl:ENST00000296679.9(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0006914""(autophagy)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0032045""(guanyl-nucleotide exchange factor complex)|go:""GO:0045920""(negative regulation of exocytosis)|go:""GO:0050777""(negative regulation of immune response)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR040102|mint:Q9HAD4|rcsb pdb:6LT0|rcsb pdb:6V4U|rcsb pdb:7MGE|rcsb pdb:8W3V|panther:PTHR22805(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:DrOZwpzvIfPWDIrWKfgEFDy3uPU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9BQA1	intact:EBI-27055528	intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym)|uniprotkb:Methylosome protein 50(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_077007.1|refseq:NP_001303993.1|refseq:NP_001303991.1|refseq:NP_001303992.1|ensembl:ENSG00000116455.14(gene)|ensembl:ENST00000235090.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007309""(oocyte axis specification)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008327""(methyl-CpG binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0031465""(Cul4B-RING E3 ubiquitin ligase complex)|go:""GO:0034709""(methylosome)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0060528""(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:""GO:0060767""(epithelial cell proliferation involved in prostate gland development)|go:""GO:0060770""(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR052139|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7BO7|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|rcsb pdb:7MX7|rcsb pdb:7MXA|rcsb pdb:7MXC|rcsb pdb:8VEX|rcsb pdb:7MXG|rcsb pdb:7MXN|rcsb pdb:7S0U|rcsb pdb:7S1P|rcsb pdb:7S1Q|rcsb pdb:7S1R|rcsb pdb:7S1S|rcsb pdb:7SER|rcsb pdb:7SES|rcsb pdb:7U30|rcsb pdb:7UOH|rcsb pdb:7UY1|rcsb pdb:7UYF|rcsb pdb:7ZUP|rcsb pdb:7ZUQ|rcsb pdb:7ZUU|rcsb pdb:7ZUY|rcsb pdb:7ZV2|rcsb pdb:7ZVL|rcsb pdb:7ZVU|rcsb pdb:8CSG|rcsb pdb:8CTB|rcsb pdb:8CYI|rcsb pdb:8G1U|rcsb pdb:8VEO|rcsb pdb:8VET|rcsb pdb:8VEU|rcsb pdb:8VEW|rcsb pdb:8VEY|rcsb pdb:9C10|rcsb pdb:9EYU|rcsb pdb:9EYV|rcsb pdb:9EYW|rcsb pdb:9EYX|reactome:R-HSA-191859|reactome:R-HSA-3214858|dip:DIP-38172N|panther:PTHR46853(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:0q4wunYtHalObC8r1wphhelIpr49606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P09543	intact:EBI-27055528	intact:EBI-1059219|intact:EBI-1188262|ensembl:ENSP00000377470.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:cn37_human(display_long)|uniprotkb:CNP(gene name)|psi-mi:CNP(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_149124.3|refseq:XP_011522642.1|ensembl:ENSG00000173786.17(gene)|ensembl:ENST00000393892.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004113""(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005874""(microtubule)|go:""GO:0005902""(microvillus)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007409""(axonogenesis)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0009214""(cyclic nucleotide catabolic process)|go:""GO:0009636""(response to toxic substance)|go:""GO:0016020""(membrane)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030551""(cyclic nucleotide binding)|go:""GO:0030900""(forebrain development)|go:""GO:0031143""(pseudopodium)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0042470""(melanosome)|go:""GO:0045202""(synapse)|go:""GO:0046902""(regulation of mitochondrial membrane permeability)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|interpro:IPR047325|mint:P09543|rcsb pdb:1WOJ|refseq:NP_001317145.1|panther:PTHR10156(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:TpzVM789s3qQKK7B00Vo92s31bY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q92625	intact:EBI-27055528	intact:EBI-1048612|uniprotkb:Q5JYI9|uniprotkb:Q5SYR2|uniprotkb:Q86WQ7|uniprotkb:A2RUC1|ensembl:ENSP00000353518.3|uniprotkb:B4DQW8	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ans1a_human(display_long)|uniprotkb:Odin(gene name synonym)|uniprotkb:ANKS1A(gene name)|psi-mi:ANKS1A(display_short)|uniprotkb:ANKS1(gene name synonym)|uniprotkb:KIAA0229(gene name synonym)|uniprotkb:ODIN(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_056060.2|ensembl:ENSG00000064999.16(gene)|ensembl:ENST00000360359.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006929""(substrate-dependent cell migration)|go:""GO:0016322""(neuron remodeling)|go:""GO:0043005""(neuron projection)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033635|interpro:IPR036770|interpro:IPR041880|interpro:IPR041882|mint:Q92625|rcsb pdb:2LMR|rcsb pdb:2MYQ|rcsb pdb:6F7O|panther:PTHR24174(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:VTw7RU5nIxHSxvQdBUT/YFlQzU89606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P08238	intact:EBI-27055664	intact:EBI-352572|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0|ensembl:ENSP00000325875.3|ensembl:ENSP00000360609.1|ensembl:ENSP00000360709.5|ensembl:ENSP00000481908.1|intact:EBI-26518782	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:HSPC3(gene name synonym)|uniprotkb:Heat shock protein family C member 3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_031381.2|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|ensembl:ENSG00000096384.20(gene)|ensembl:ENST00000353801.7(transcript)|ensembl:ENST00000371554.2(transcript)|ensembl:ENST00000371646.10(transcript)|ensembl:ENST00000620073.4(transcript)|go:""GO:0001890""(placenta development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007004""(telomere maintenance via telomerase)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019062""(virion attachment to host cell)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030235""(nitric-oxide synthase regulator activity)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030911""(TPR domain binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|rcsb pdb:8GFT|go:""GO:0032991""(protein-containing complex)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034751""(aryl hydrocarbon receptor complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042277""(peptide binding)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043008""(ATP-dependent protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044294""(dendritic growth cone)|go:""GO:0044295""(axonal growth cone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:0071353""(cellular response to interleukin-4)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0120293""(dynein axonemal particle)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1901799""(negative regulation of proteasomal protein catabolic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1905323""(telomerase holoenzyme complex assembly)|go:""GO:1990226""(histone methyltransferase binding)|go:""GO:1990565""(HSP90-CDC37 chaperone complex)|go:""GO:2000010""(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|rcsb pdb:7ULJ|rcsb pdb:7Z37|rcsb pdb:7Z38|rcsb pdb:7ZR0|rcsb pdb:7ZR5|rcsb pdb:7ZR6|rcsb pdb:7ZUB|rcsb pdb:8EOA|rcsb pdb:8EOB|rcsb pdb:8GAE|rcsb pdb:8QMO|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|reactome:R-HSA-9705671|reactome:R-HSA-9820962|reactome:R-HSA-9834752|dip:DIP-413N|panther:PTHR11528(orthology-group)|ensembl:ENSP00000325875.3|ensembl:ENSP00000360609.1|ensembl:ENSP00000360709.5|ensembl:ENSP00000481908.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:wOsW7C10v2oMsM+REE38K6PAan09606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q9Y265	intact:EBI-27055664	intact:EBI-353675|uniprotkb:P82276|ensembl:ENSP00000318297.5|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_003698.1|ensembl:ENSG00000175792.12(gene)|ensembl:ENST00000322623.10(transcript)|go:""GO:0000492""(box C/D snoRNP assembly)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000786""(nucleosome)|go:""GO:0000812""(Swr1 complex)|go:""GO:0001094""(TFIID-class transcription factor complex binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006282""(regulation of DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007283""(spermatogenesis)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017025""(TBP-class protein binding)|go:""GO:0031011""(Ino80 complex)|go:""GO:0033044""(regulation of chromosome organization)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043531""(ADP binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0050821""(protein stabilization)|go:""GO:0051117""(ATPase binding)|go:""GO:0051301""(cell division)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060382""(regulation of DNA strand elongation)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071339""(MLL1 complex)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090671""(telomerase RNA localization to Cajal body)|go:""GO:0097255""(R2TP complex)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0120293""(dynein axonemal particle)|interpro:IPR027238|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1904507""(positive regulation of telomere maintenance in response to DNA damage)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000779""(regulation of double-strand break repair)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027417|interpro:IPR041048|interpro:IPR042487|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|rcsb pdb:7OLE|rcsb pdb:7P6X|rcsb pdb:7ZI4|rcsb pdb:8QR1|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|rcsb pdb:8XVG|rcsb pdb:8XVT|rcsb pdb:9C57|rcsb pdb:9C62|rcsb pdb:9EMA|rcsb pdb:9EMC|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|refseq:NP_001306013.1|dip:DIP-29937N|panther:PTHR11093(orthology-group)|ensembl:ENSP00000318297.5"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q9Y230	intact:EBI-27055664	intact:EBI-352939|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|intact:EBI-1058527|ensembl:ENSP00000473172.1|uniprotkb:B3KQ59|uniprotkb:E7ETE5	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_006657.1|refseq:NP_001308120.1|ensembl:ENSG00000183207.15(gene)|ensembl:ENST00000595090.6(transcript)|go:""GO:0000492""(box C/D snoRNP assembly)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000786""(nucleosome)|go:""GO:0000791""(euchromatin)|go:""GO:0000812""(Swr1 complex)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0001094""(TFIID-class transcription factor complex binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006282""(regulation of DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006457""(protein folding)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017025""(TBP-class protein binding)|go:""GO:0031011""(Ino80 complex)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0033044""(regulation of chromosome organization)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043531""(ADP binding)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060382""(regulation of DNA strand elongation)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071169""(establishment of protein localization to chromatin)|go:""GO:0071339""(MLL1 complex)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0090671""(telomerase RNA localization to Cajal body)|go:""GO:0097255""(R2TP complex)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0120293""(dynein axonemal particle)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140585""(promoter-enhancer loop anchoring activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1904507""(positive regulation of telomere maintenance in response to DNA damage)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000779""(regulation of double-strand break repair)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|rcsb pdb:7OLE|rcsb pdb:7P6X|rcsb pdb:7ZI4|rcsb pdb:8QR1|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|rcsb pdb:8XVG|rcsb pdb:8XVT|rcsb pdb:9C57|rcsb pdb:9C62|rcsb pdb:9EMA|rcsb pdb:9EMC|reactome:R-HSA-171319|reactome:R-HSA-3214847|refseq:XP_011524632.1|dip:DIP-28153N|panther:PTHR11093(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P07900	intact:EBI-27055664	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9|ensembl:ENSP00000216281.8	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)|uniprotkb:Heat shock protein family C member 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001017963.2|refseq:NP_005339.3|ensembl:ENSG00000080824.19(gene)|ensembl:ENST00000216281.13(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0002134""(UTP binding)|go:""GO:0002135""(CTP binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0002230""(positive regulation of defense response to virus by host)|go:""GO:0003009""(skeletal muscle contraction)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006457""(protein folding)|go:""GO:0006839""(mitochondrial transport)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007004""(telomere maintenance via telomerase)|go:""GO:0009408""(response to heat)|go:""GO:0009409""(response to cold)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009651""(response to salt stress)|go:""GO:0009986""(cell surface)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010659""(cardiac muscle cell apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017098""(sulfonylurea receptor binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030235""(nitric-oxide synthase regulator activity)|go:""GO:0030911""(TPR domain binding)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031526""(brush border membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0032273""(positive regulation of protein polymerization)|go:""GO:0032564""(dATP binding)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042220""(response to cocaine)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043209""(myelin sheath)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043335""(protein unfolding)|go:""GO:0043627""(response to estrogen)|go:""GO:0044294""(dendritic growth cone)|go:""GO:0044295""(axonal growth cone)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045040""(protein insertion into mitochondrial outer membrane)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045793""(positive regulation of cell size)|go:""GO:0046677""(response to antibiotic)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051020""(GTPase binding)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0060452""(positive regulation of cardiac muscle contraction)|go:""GO:0061684""(chaperone-mediated autophagy)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097226""(sperm mitochondrial sheath)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098586""(cellular response to virus)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1902988""(neurofibrillary tangle assembly)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1905323""(telomerase holoenzyme complex assembly)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|rcsb pdb:1UY8|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2BYH|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2VCJ|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:3B24|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:3K99|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:3T0H|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:4YKZ|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|rcsb pdb:5LO1|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6CYH|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN4|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7DMC|rcsb pdb:7KRJ|rcsb pdb:7KW7|rcsb pdb:7L7I|rcsb pdb:7L7J|rcsb pdb:7LSZ|rcsb pdb:7LT0|rcsb pdb:7RXZ|rcsb pdb:7RY0|rcsb pdb:7RY1|rcsb pdb:7S8Y|rcsb pdb:7S8Z|rcsb pdb:7S90|rcsb pdb:7S95|rcsb pdb:7S98|rcsb pdb:7S99|rcsb pdb:7S9F|rcsb pdb:7S9G|rcsb pdb:7S9H|rcsb pdb:7S9I|rcsb pdb:7UR3|rcsb pdb:8AGI|rcsb pdb:8AGJ|rcsb pdb:8AGL|rcsb pdb:8B7I|rcsb pdb:8B7J|rcsb pdb:8FFV|rcsb pdb:8FFW|rcsb pdb:8KI4|rcsb pdb:8SBT|rcsb pdb:8W4V|rcsb pdb:8W8K|rcsb pdb:8X2R|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|reactome:R-HSA-9705671|reactome:R-HSA-9820962|reactome:R-HSA-9834752|dip:DIP-27595N|ensembl:ENSP00000335153.7|ensembl:ENSP00000216281.8|ensembl:ENST00000334701.11|panther:PTHR11528(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P78371	intact:EBI-27055664	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300.6	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"panther:PTHR11353(orthology-group)|refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226.13(gene)|ensembl:ENST00000299300.11(transcript)|go:""GO:0002199""(zona pellucida receptor complex)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044297""(cell body)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090666""(scaRNA localization to Cajal body)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR053374|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7TUB|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHD|rcsb pdb:8SHE|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P51798	intact:EBI-27055664	intact:EBI-4402346|uniprotkb:A6NEJ7|uniprotkb:A8K5T9|uniprotkb:Q9NYX5|uniprotkb:A8K7X1|uniprotkb:B3KPN3|uniprotkb:E9PDB9|ensembl:ENSP00000372193.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:clcn7_human(display_long)|uniprotkb:CLCN7(gene name)|psi-mi:CLCN7(display_short)|uniprotkb:Chloride channel protein 7(gene name synonym)|uniprotkb:Chloride channel 7 alpha subunit(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000103249.19(gene)|ensembl:ENST00000382745.9(transcript)|go:""GO:0005247""(voltage-gated chloride channel activity)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0015108""(chloride transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0016020""(membrane)|go:""GO:0030321""(transepithelial chloride transport)|go:""GO:0034707""(chloride channel complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002249(Chloride channel CLC-7)|interpro:IPR014743(Chloride channel, core)|interpro:IPR046342|interpro:IPR051280|mint:P51798|rcsb pdb:7BXU|rcsb pdb:7CQ5|rcsb pdb:7CQ6|rcsb pdb:7CQ7|rcsb pdb:7JM7|rcsb pdb:8HVT|reactome:R-HSA-2672351|refseq:NP_001107803.1|refseq:NP_001278.1|efo:""Orphanet:210110""|efo:""Orphanet:53""|efo:""Orphanet:667""|panther:PTHR11689(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:ze820JsKN1GtxH/lcPnPWN78k1I9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q9Y2Z0	intact:EBI-27055664	intact:EBI-307008|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6|ensembl:ENSP00000367208.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001124384.1|refseq:NP_006695.1|ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000343788.10(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007051""(spindle organization)|go:""GO:0014841""(skeletal muscle satellite cell proliferation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032991""(protein-containing complex)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0106222""(lncRNA binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|reactome:R-HSA-9660826|refseq:NP_001307760.1|dip:DIP-53799N|panther:PTHR45862(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P51149	intact:EBI-27055664	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062.3|ensembl:ENSP00000501618.1|ensembl:ENSP00000502000.1|ensembl:ENSP00000502088.1|ensembl:ENSP00000502486.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000075785.14(gene)|ensembl:ENST00000265062.8(transcript)|ensembl:ENST00000674589.1(transcript)|ensembl:ENST00000675342.1(transcript)|ensembl:ENST00000675497.1(transcript)|ensembl:ENST00000676214.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0019003""(GDP binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0036466""(synaptic vesicle recycling via endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045453""(bone resorption)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048524""(positive regulation of viral process)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090383""(phagosome acidification)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0097208""(alveolar lamellar body)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:1903542""(negative regulation of exosomal secretion)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1905366""(negative regulation of intralumenal vesicle formation)|go:""GO:1905394""(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:3LAW|rcsb pdb:6IYB|rcsb pdb:6WCW|rcsb pdb:7F6J|rcsb pdb:8KB8|rcsb pdb:8ZQ3|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|refseq:NP_004628.4|efo:""Orphanet:99936""|dip:DIP-39879N|panther:PTHR47981(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O15498	intact:EBI-27055664	intact:EBI-4402903|uniprotkb:Q53F01|uniprotkb:Q6FGU9|uniprotkb:Q6IB15|uniprotkb:B4DR94|ensembl:ENSP00000223369.2|ensembl:ENSP00000504623.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ykt6_human(display_long)|uniprotkb:YKT6(gene name)|psi-mi:YKT6(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_006546.1|refseq:XP_016867171.1|ensembl:ENSG00000106636.9(gene)|ensembl:ENST00000223369.3(transcript)|ensembl:ENST00000679020.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006903""(vesicle targeting)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0030133""(transport vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045296""(cadherin binding)|go:""GO:0097440""(apical dendrite)|go:""GO:0097441""(basal dendrite)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR045848|mint:O15498|rcsb pdb:6J74|rcsb pdb:6J7F|rcsb pdb:6J7X|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9013423|panther:PTHR45806(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:pkTOoQ9XXEVYHKNvqOMCU6x4nZg9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q7Z3T8	intact:EBI-27055664	intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|uniprotkb:Q5H9U2|ensembl:ENSP00000337159.5|ensembl:ENSP00000423663.1|ensembl:ENSP00000426848.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000039319.17(gene)|ensembl:ENST00000338008.9(transcript)|ensembl:ENST00000505560.5(transcript)|ensembl:ENST00000510158.5(transcript)|go:""GO:0005545""(1-phosphatidylinositol binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0007165""(signal transduction)|go:""GO:0016050""(vesicle organization)|go:""GO:0016197""(endosomal transport)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0031901""(early endosome membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|mint:Q7Z3T8|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_005248689.1|refseq:XP_011542055.1|refseq:XP_016865580.1|refseq:XP_016865581.1|panther:PTHR46319(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q99729	intact:EBI-27055664	intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_004490.2|refseq:NP_112556.2|mint:Q99729|dip:DIP-50394N|go:""GO:0000785""(chromatin)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016556""(mRNA modification)|go:""GO:0030425""(dendrite)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045293""(mRNA editing complex)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071598""(neuronal ribonucleoprotein granule)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0141166""(chromosomal 5-methylcytosine DNA demethylation pathway)|go:""GO:1904580""(regulation of intracellular mRNA localization)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000623""(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|panther:PTHR48033(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q3SXY8	intact:EBI-27055664	intact:EBI-11343438|uniprotkb:Q8TCL5|uniprotkb:Q504W8|uniprotkb:G3V1S8|uniprotkb:D3DN29|ensembl:ENSP00000377769.3|ensembl:ENSP00000420780.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ar13b_human(display_long)|uniprotkb:ARL13B(gene name)|psi-mi:ARL13B(display_short)|uniprotkb:ADP-ribosylation factor-like protein 2-like 1(gene name synonym)|uniprotkb:ARL2L1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000169379.17(gene)|ensembl:ENST00000394222.8(transcript)|ensembl:ENST00000471138.5(transcript)|go:""GO:0001947""(heart looping)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0005930""(axoneme)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0009953""(dorsal/ventral pattern formation)|go:""GO:0021532""(neural tube patterning)|go:""GO:0021830""(interneuron migration from the subpallium to the cortex)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0031514""(motile cilium)|go:""GO:0060170""(ciliary membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0070986""(left/right axis specification)|go:""GO:0097500""(receptor localization to non-motile cilium)|go:""GO:0097730""(non-motile cilium)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR051995|mint:Q3SXY8|reactome:R-HSA-5624958|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:NP_001167621.1|refseq:NP_001167622.1|refseq:NP_659433.2|refseq:NP_878899.1|refseq:XP_016861342.1|panther:PTHR46090(orthology-group)|efo:""Orphanet:475"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:4+UUoBstGIB4bfg75vAxWj0ppd89606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O95721	intact:EBI-27055664	intact:EBI-490676|ensembl:ENSP00000215730.6	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:snp29_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-29(gene name synonym)|uniprotkb:Soluble 29 kDa NSF attachment protein(gene name synonym)|uniprotkb:SNAP29(gene name)|psi-mi:SNAP29(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000099940.12(gene)|ensembl:ENST00000215730.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005776""(autophagosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006903""(vesicle targeting)|go:""GO:0015031""(protein transport)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0016240""(autophagosome membrane docking)|go:""GO:0019905""(syntaxin binding)|go:""GO:0020018""(ciliary pocket membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0061025""(membrane fusion)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098793""(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|mint:O95721|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-6798695|reactome:R-HSA-6811438|refseq:NP_004773.1|efo:""Orphanet:66631""|dip:DIP-56475N|panther:PTHR19305(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:4HyjERPnEDdBgiGt70N9oyrMN1k9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P31689	intact:EBI-27055664	intact:EBI-347834|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9|ensembl:ENSP00000369127.3	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000086061.16(gene)|ensembl:ENST00000330899.5(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007283""(spermatogenesis)|go:""GO:0009408""(response to heat)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042026""(protein refolding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043508""(negative regulation of JUN kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051223""(regulation of protein transport)|go:""GO:0055131""(C3HC4-type RING finger domain binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070585""(protein localization to mitochondrion)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:1903748""(negative regulation of establishment of protein localization to mitochondrion)|go:""GO:1905259""(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|rcsb pdb:6E8M|rcsb pdb:8E2O|reactome:R-HSA-3371497|reactome:R-HSA-9841251|refseq:NP_001530.1|panther:PTHR43888(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P23528	intact:EBI-27055664	intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629.5|ensembl:ENSP00000432660.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_005498.1|ensembl:ENSG00000172757.13(gene)|ensembl:ENST00000308162.10(transcript)|ensembl:ENST00000525451.6(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0009615""(response to virus)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030043""(actin filament fragmentation)|go:""GO:0030426""(growth cone)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032587""(ruffle membrane)|go:""GO:0040019""(positive regulation of embryonic development)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0051293""(establishment of spindle localization)|go:""GO:0061001""(regulation of dendritic spine morphogenesis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|dip:DIP-33000N|panther:PTHR11913(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q9Y277	intact:EBI-27055664	intact:EBI-354196|uniprotkb:Q9UIS0|ensembl:ENSP00000022615.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:vdac3_human(display_long)|uniprotkb:VDAC3(gene name)|psi-mi:VDAC3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001129166.1|refseq:NP_005653.3|ensembl:ENSG00000078668.14(gene)|ensembl:ENST00000022615.9(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0001662""(behavioral fear response)|go:""GO:0005244""(voltage-gated monoatomic ion channel activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0007270""(neuron-neuron synaptic transmission)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007612""(learning)|go:""GO:0008308""(voltage-gated monoatomic anion channel activity)|go:""GO:0015288""(porin activity)|go:""GO:0015853""(adenine transport)|go:""GO:0016020""(membrane)|go:""GO:0045202""(synapse)|go:""GO:0046930""(pore complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120317""(sperm mitochondrial sheath assembly)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|mint:Q9Y277|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-8949215|panther:PTHR11743(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:En6g89Dp+C4s1ArGYJyVfUBVsO09606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O00161	intact:EBI-27055664	intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647.3	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_003816.2|refseq:NP_570710.1|refseq:XP_016878183.1|ensembl:ENSG00000092531.10(gene)|ensembl:ENST00000249647.8(transcript)|go:""GO:0002553""(histamine secretion by mast cell)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006887""(exocytosis)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006903""(vesicle targeting)|go:""GO:0015031""(protein transport)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042581""(specific granule)|go:""GO:0042582""(azurophil granule)|go:""GO:0043005""(neuron projection)|go:""GO:0061025""(membrane fusion)|go:""GO:0070032""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0098793""(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR19305(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P07910	intact:EBI-27055664	intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|ensembl:ENSP00000404848.2|ensembl:ENSP00000451291.1|ensembl:ENSP00000452276.1|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000092199.19(gene)|ensembl:ENST00000420743.6(transcript)|ensembl:ENST00000554455.5(transcript)|ensembl:ENST00000557201.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000785""(chromatin)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005697""(telomerase holoenzyme complex)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008380""(RNA splicing)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0070034""(telomerase RNA binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1990247""(N6-methyladenosine-containing RNA reader activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|interpro:IPR051186|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|refseq:XP_006720188.1|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|efo:""Orphanet:528084""|dip:DIP-29854N|panther:PTHR13968(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P54886	intact:EBI-27055664	intact:EBI-1210304|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44|ensembl:ENSP00000360268.2	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000059573.9(gene)|ensembl:ENST00000371224.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004349""(glutamate 5-kinase activity)|go:""GO:0004350""(glutamate-5-semialdehyde dehydrogenase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006536""(glutamate metabolic process)|go:""GO:0006561""(proline biosynthetic process)|go:""GO:0006592""(ornithine biosynthetic process)|go:""GO:0009266""(response to temperature stimulus)|go:""GO:0019240""(citrulline biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539|reactome:R-HSA-9837999|refseq:NP_001017423.1|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|refseq:NP_002851.2|efo:""Orphanet:35664""|efo:""Orphanet:447753""|efo:""Orphanet:447757""|efo:""Orphanet:447760""|efo:""Orphanet:90348""|panther:PTHR11063(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P51991	intact:EBI-27055664	intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309.2|ensembl:ENSP00000416340.1|ensembl:ENSP00000503593.1|ensembl:ENSP00000504135.1|ensembl:ENSP00000504152.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144.23(gene)|ensembl:ENST00000392524.7(transcript)|ensembl:ENST00000435711.5(transcript)|ensembl:ENST00000676629.1(transcript)|ensembl:ENST00000678111.1(transcript)|ensembl:ENST00000679159.1(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203|panther:PTHR48026(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P68371	intact:EBI-27055664	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"efo:""Orphanet:65""|ensembl:ENSG00000188229.6(gene)|ensembl:ENST00000340384.5(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0005879""(axonemal microtubule)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0036126""(sperm flagellum)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0045171""(intercellular bridge)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072686""(mitotic spindle)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|rcsb pdb:7UN1|rcsb pdb:7UNG|rcsb pdb:8J07|rcsb pdb:8SH7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9833482|refseq:NP_006079.1|panther:PTHR11588(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O60884	intact:EBI-27055664	intact:EBI-352957|uniprotkb:O14711|uniprotkb:B2R7L7|ensembl:ENSP00000314030.5|intact:EBI-21358170	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_005871.1|ensembl:ENSG00000069345.12(gene)|ensembl:ENST00000317089.10(transcript)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|rcsb pdb:7ZHS|reactome:R-HSA-3371497|dip:DIP-33143N|panther:PTHR43888(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P21796	intact:EBI-27055664	intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|ensembl:ENSP00000265333.3|ensembl:ENSP00000378484.3|ensembl:ENSP00000378487.2|uniprotkb:B3KVK4|uniprotkb:D3DQ93	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym)|uniprotkb:Voltage-dependent anion-selective channel protein 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000213585.11(gene)|ensembl:ENST00000265333.8(transcript)|ensembl:ENST00000395044.7(transcript)|ensembl:ENST00000395047.6(transcript)|go:""GO:0001662""(behavioral fear response)|go:""GO:0005244""(voltage-gated monoatomic ion channel activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005757""(mitochondrial permeability transition pore complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006820""(monoatomic anion transport)|go:""GO:0006869""(lipid transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007270""(neuron-neuron synaptic transmission)|go:""GO:0007612""(learning)|go:""GO:0008142""(oxysterol binding)|go:""GO:0008308""(voltage-gated monoatomic anion channel activity)|go:""GO:0015288""(porin activity)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0036444""(calcium import into the mitochondrion)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0046930""(pore complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097001""(ceramide binding)|go:""GO:0110099""(negative regulation of calcium import into the mitochondrion)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1990542""(mitochondrial transmembrane transport)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|rcsb pdb:7QI2|rcsb pdb:8J0O|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215|refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|panther:PTHR11743(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q6IAA8	intact:EBI-27055664	intact:EBI-715385|uniprotkb:Q8WZ09|uniprotkb:Q9NWT0|ensembl:ENSP00000278671.5	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ltor1_human(display_long)|uniprotkb:LAMTOR1(gene name)|psi-mi:LAMTOR1(display_short)|uniprotkb:PP7157(orf name)|uniprotkb:p27Kip1-releasing factor from RhoA(gene name synonym)|uniprotkb:C11orf59(gene name synonym)|uniprotkb:Lipid raft adaptor protein p18(gene name synonym)|uniprotkb:Protein associated with DRMs and endosomes(gene name synonym)|uniprotkb:PDRO(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_060377.1|dip:DIP-39650N|ensembl:ENSG00000149357.10(gene)|ensembl:ENST00000278671.10(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001919""(regulation of receptor recycling)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007032""(endosome organization)|go:""GO:0007040""(lysosome organization)|go:""GO:0008104""(protein localization)|go:""GO:0010874""(regulation of cholesterol efflux)|go:""GO:0016197""(endosomal transport)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0032418""(lysosome localization)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045121""(membrane raft)|go:""GO:0051020""(GTPase binding)|go:""GO:0060620""(regulation of cholesterol import)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071986""(Ragulator complex)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0150032""(positive regulation of protein localization to lysosome)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990877""(FNIP-folliculin RagC/D GAP)|interpro:IPR028209|mint:Q6IAA8|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6B9X|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|rcsb pdb:6WJ2|rcsb pdb:6WJ3|rcsb pdb:7T3A|rcsb pdb:7T3B|rcsb pdb:7T3C|rcsb pdb:7UX2|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8DHB|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6798695|reactome:R-HSA-8943724|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9639288|panther:PTHR13401(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:qOdH2HiC+MXwRS2+L8/XgkTRDeo9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q15836	intact:EBI-27055664	intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666.6	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_004772.1|ensembl:ENSG00000049245.13(gene)|ensembl:ENST00000054666.11(transcript)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0030133""(transport vesicle)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061025""(membrane fusion)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:1903531""(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-56422N|panther:PTHR45701(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O43175	intact:EBI-27055664	intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|uniprotkb:B2RD08|ensembl:ENSP00000493175.1|ensembl:ENSP00000493382.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"efo:""Orphanet:583607""|efo:""Orphanet:79351""|ensembl:ENSG00000092621.13(gene)|ensembl:ENST00000641023.2(transcript)|ensembl:ENST00000641597.1(transcript)|go:""GO:0004617""(phosphoglycerate dehydrogenase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0006544""(glycine metabolic process)|go:""GO:0006564""(L-serine biosynthetic process)|go:""GO:0006566""(threonine metabolic process)|go:""GO:0007420""(brain development)|go:""GO:0009055""(electron transfer activity)|go:""GO:0009448""(gamma-aminobutyric acid metabolic process)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0019530""(taurine metabolic process)|go:""GO:0021510""(spinal cord development)|go:""GO:0021782""(glial cell development)|go:""GO:0021915""(neural tube development)|go:""GO:0030060""(""L-malate dehydrogenase (NAD+) activity"")|go:""GO:0031175""(neuron projection development)|go:""GO:0051287""(NAD binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070314""(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR045626|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|rcsb pdb:7DKM|rcsb pdb:7EWH|rcsb pdb:7VA1|reactome:R-HSA-977347|refseq:NP_006614.2|panther:PTHR42938(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q99618	intact:EBI-27055664	intact:EBI-739534|uniprotkb:A8K5V6|uniprotkb:D3DUS6|ensembl:ENSP00000442068.1|ensembl:ENSP00000446339.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:cdca3_human(display_long)|uniprotkb:CDCA3(gene name)|psi-mi:CDCA3(display_short)|uniprotkb:Trigger of mitotic entry protein 1(gene name synonym)|uniprotkb:Gene-rich cluster protein C8(gene name synonym)|uniprotkb:C8(gene name synonym)|uniprotkb:GRCC8(gene name synonym)|uniprotkb:TOME1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_112589.1|ensembl:ENSG00000111665.12(gene)|ensembl:ENST00000535406.5(transcript)|ensembl:ENST00000538862.7(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005912""(adherens junction)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0051301""(cell division)|interpro:IPR038832|mint:Q99618|refseq:NP_001284532.1|refseq:NP_001284533.1|refseq:NP_001317948.1|panther:PTHR34756(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:UmhACVP83jo9/xqP7qDSSvKgiAo9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P31948	intact:EBI-27055664	intact:EBI-1054052|uniprotkb:Q5TZU9|intact:EBI-4404694|uniprotkb:B4DM70|uniprotkb:F5H0T1|uniprotkb:G3XAD8|uniprotkb:Q3ZCU9|ensembl:ENSP00000305958.5	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:stip1_human(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:STIP1(gene name)|psi-mi:STIP1(display_short)|uniprotkb:Transformation-sensitive protein IEF SSP 3521(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-11(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_006810.1|refseq:NP_001269581.1|refseq:NP_001269582.1|dip:DIP-41085N|ensembl:ENSG00000168439.17(gene)|ensembl:ENST00000305218.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0032991""(protein-containing complex)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0120293""(dynein axonemal particle)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR041243|mint:P31948|rcsb pdb:1ELR|rcsb pdb:1ELW|rcsb pdb:2LNI|rcsb pdb:2NC9|rcsb pdb:3ESK|rcsb pdb:3FWV|rcsb pdb:7KW7|reactome:R-HSA-3371497|reactome:R-HSA-9696273|panther:PTHR22904(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:/encEzabIj7I9YdYaYY2UvRG3Pg9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q86Y82	intact:EBI-27055664	intact:EBI-2691717|uniprotkb:B1AJQ7|uniprotkb:O95564|ensembl:ENSP00000363054.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:stx12_human(display_long)|uniprotkb:STX12(gene name)|psi-mi:STX12(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_803173.1|dip:DIP-44225N|ensembl:ENSG00000117758.14(gene)|ensembl:ENST00000373943.9(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000149""(SNARE binding)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0012505""(endomembrane system)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032456""(endocytic recycling)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045121""(membrane raft)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048278""(vesicle docking)|go:""GO:0050821""(protein stabilization)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0098837""(postsynaptic recycling endosome)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR045242|mint:Q86Y82|rcsb pdb:2DNX|panther:PTHR19957(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:kSTOaE08HK8SpI19dBZRZbOVCGw9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:A0A1W2PQS6	intact:EBI-27055664	intact:EBI-27056243|ensembl:ENSP00000491891.1|ensembl:ENSP00000492441.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:a0a1w2pqs6_human(display_long)|uniprotkb:40S ribosomal protein S10(gene name synonym)|uniprotkb:RPS10-NUDT3(gene name)|psi-mi:RPS10-NUDT3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000270800.4(gene)|ensembl:ENST00000639725.1(transcript)|ensembl:ENST00000639877.1(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0016462""(pyrophosphatase activity)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036388|interpro:IPR037447|interpro:IPR047198|refseq:NP_001189399.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:Ao3eAepmo782rGKLMnJBL9TP6wU9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O15400	intact:EBI-27055664	intact:EBI-3221827|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579|ensembl:ENSP00000356918.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N|go:""GO:0005765""(lysosomal membrane)|ensembl:ENSG00000079950.14(gene)|ensembl:ENST00000367941.7(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0012505""(endomembrane system)|go:""GO:0019869""(chloride channel inhibitor activity)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0042582""(azurophil granule)|go:""GO:0048278""(vesicle docking)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051640""(organelle localization)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070820""(tertiary granule)|go:""GO:0070925""(organelle assembly)|go:""GO:1902685""(positive regulation of receptor localization to synapse)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR045242|mint:O15400|panther:PTHR19957(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:lFaq26g0qeP7ObMMKexuZamQgps9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q9UEU0	intact:EBI-27055664	intact:EBI-723716|uniprotkb:O43547|uniprotkb:Q96J28|ensembl:ENSP00000450731.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:vti1b_human(display_long)|uniprotkb:Vesicle transport v-SNARE protein Vti1-like 1(gene name synonym)|uniprotkb:Vti1-rp1(gene name synonym)|uniprotkb:VTI1B(gene name)|psi-mi:VTI1B(display_short)|uniprotkb:VTI1(gene name synonym)|uniprotkb:VTI1L(gene name synonym)|uniprotkb:VTI1L1(gene name synonym)|uniprotkb:VTI2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_006361.1|ensembl:ENSG00000100568.11(gene)|ensembl:ENST00000554659.6(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0019869""(chloride channel inhibitor activity)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048280""(vesicle fusion with Golgi apparatus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061025""(membrane fusion)|go:""GO:0098954""(presynaptic endosome membrane)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR038407|mint:Q9UEU0|rcsb pdb:2V8S|reactome:R-HSA-114608|panther:PTHR21230(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:jJgdeKpTRzoaVS5zj+cPGKj05OM9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P78310	intact:EBI-27055664	intact:EBI-747931|uniprotkb:O00694|uniprotkb:Q8WWT6|uniprotkb:Q8WWT7|uniprotkb:Q8WWT8|uniprotkb:Q9UKV4|uniprotkb:B2R8V8|ensembl:ENSP00000284878.7|uniprotkb:B7WPI3|uniprotkb:D3YHP0	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:cxar_human(display_long)|uniprotkb:Coxsackievirus B-adenovirus receptor(gene name synonym)|uniprotkb:HCVADR(gene name synonym)|uniprotkb:CVB3-binding protein(gene name synonym)|uniprotkb:CXADR(gene name)|psi-mi:CXADR(display_short)|uniprotkb:CAR(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001329.1|refseq:NP_001193992.1|refseq:NP_001193993.1|refseq:NP_001193994.1|ensembl:ENSG00000154639.19(gene)|ensembl:ENST00000284878.12(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007507""(heart development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008354""(germ cell migration)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0014704""(intercalated disc)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030175""(filopodium)|go:""GO:0030426""(growth cone)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034109""(homotypic cell-cell adhesion)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0044297""(cell body)|go:""GO:0045121""(membrane raft)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0046629""(gamma-delta T cell activation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0055013""(cardiac muscle cell development)|go:""GO:0070633""(transepithelial transport)|go:""GO:0071253""(connexin binding)|go:""GO:0086067""(AV node cell to bundle of His cell communication)|go:""GO:0086072""(AV node cell-bundle of His cell adhesion involved in cell communication)|go:""GO:0086082""(cell adhesive protein binding involved in AV node cell-bundle of His cell communication)|go:""GO:0098904""(regulation of AV node cell action potential)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR052307|mint:P78310|rcsb pdb:1EAJ|rcsb pdb:1F5W|rcsb pdb:1JEW|rcsb pdb:1KAC|rcsb pdb:1P69|rcsb pdb:1P6A|rcsb pdb:1RSF|rcsb pdb:2J12|rcsb pdb:2J1K|rcsb pdb:2NPL|rcsb pdb:2W9L|rcsb pdb:2WBW|rcsb pdb:3J6L|rcsb pdb:3J6M|rcsb pdb:3J6N|rcsb pdb:3J6O|rcsb pdb:7DPZ|rcsb pdb:7DQ1|rcsb pdb:7VXZ|rcsb pdb:7VYK|rcsb pdb:7VYL|rcsb pdb:7VYM|rcsb pdb:7W14|reactome:R-HSA-198933|reactome:R-HSA-202733|refseq:NP_001193995.1|refseq:XP_011527781.1|panther:PTHR44468(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:rISYMOJkhS94FeOElTtG8w5p4hI9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q9UNK0	intact:EBI-27055664	intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255.2	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_004844.1|ensembl:ENSG00000170310.15(gene)|ensembl:ENST00000306357.9(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0012505""(endomembrane system)|go:""GO:0019869""(chloride channel inhibitor activity)|go:""GO:0019905""(syntaxin binding)|go:""GO:0031201""(SNARE complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048278""(vesicle docking)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|interpro:IPR045242|mint:Q9UNK0|dip:DIP-47274N|panther:PTHR19957(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:jdsUOdy99aWRb94ndPtawff7z/o9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q9BVA1	intact:EBI-27055664	intact:EBI-355665|uniprotkb:A8K068|ensembl:ENSP00000259818.6	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:tbb2b_human(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"efo:""Orphanet:1766""|efo:""Orphanet:300573""|efo:""Orphanet:45358""|efo:""Orphanet:467166""|ensembl:ENSG00000137285.11(gene)|ensembl:ENST00000259818.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001764""(neuron migration)|go:""GO:0003924""(GTPase activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005874""(microtubule)|go:""GO:0007017""(microtubule-based process)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0045171""(intercellular bridge)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0072686""(mitotic spindle)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:1902669""(positive regulation of axon guidance)|go:""GO:1990403""(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BVA1|rcsb pdb:6E7C|rcsb pdb:7ZCW|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9833482|refseq:NP_821080.1|panther:PTHR11588(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:sluQMryNuOvp6xlV558+agiRwvE9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P61221	intact:EBI-27055664	intact:EBI-2510446|uniprotkb:Q6NR76|uniprotkb:O88793|uniprotkb:Q13181|uniprotkb:Q99K66|uniprotkb:Q13864|uniprotkb:Q96AL0|uniprotkb:Q96B10|ensembl:ENSP00000296577.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:abce1_human(display_long)|uniprotkb:ABCE1(gene name)|psi-mi:ABCE1(display_short)|uniprotkb:RLI(gene name synonym)|uniprotkb:RNASEL1(gene name synonym)|uniprotkb:RNASELI(gene name synonym)|uniprotkb:RNS4I(gene name synonym)|uniprotkb:RNase L inhibitor(gene name synonym)|uniprotkb:Ribonuclease 4 inhibitor(gene name synonym)|uniprotkb:2'-5'-oligoadenylate-binding protein(gene name synonym)|uniprotkb:HuHP68(gene name synonym)|uniprotkb:OK/SW-cl.40(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001035809.1|refseq:NP_002931.2|ensembl:ENSG00000164163.11(gene)|ensembl:ENST00000296577.9(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006415""(translational termination)|go:""GO:0006417""(regulation of translation)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017111""(ribonucleoside triphosphate phosphatase activity)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043273""(CTPase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0060698""(endoribonuclease inhibitor activity)|go:""GO:0060702""(negative regulation of endoribonuclease activity)|go:""GO:0072344""(rescue of stalled ribosome)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007209(Possible metal-binding region in RNase L inhibitor, RLI)|interpro:IPR013283(ABC transporter, ABCE)|interpro:IPR017871|interpro:IPR017896|interpro:IPR017900|interpro:IPR027417|interpro:IPR034348|mint:P61221|rcsb pdb:6ZME|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-8983711|reactome:R-HSA-909733|panther:PTHR19248(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:+6ykpRtI4p94M3TuoTzFBvdCsC09606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q02790	intact:EBI-27055664	intact:EBI-1047444|uniprotkb:D3DUQ1|uniprotkb:Q9UCP1|uniprotkb:Q9UCV7|ensembl:ENSP00000001008.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:fkbp4_human(display_long)|uniprotkb:FK506-binding protein 4(gene name synonym)|uniprotkb:HSP-binding immunophilin(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:52 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBP59(gene name synonym)|uniprotkb:Immunophilin FKBP52(gene name synonym)|uniprotkb:FKBP4(gene name)|psi-mi:FKBP4(display_short)|uniprotkb:FKBP52(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:59 kDa immunophilin(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_002005.1|ensembl:ENSG00000004478.8(gene)|ensembl:ENST00000001008.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005528""(FK506 binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0006463""(steroid hormone receptor complex assembly)|go:""GO:0006825""(copper ion transport)|go:""GO:0007566""(embryo implantation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030850""(prostate gland development)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031111""(negative regulation of microtubule polymerization or depolymerization)|go:""GO:0031115""(negative regulation of microtubule polymerization)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0032767""(copper-dependent protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035259""(nuclear glucocorticoid receptor binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044295""(axonal growth cone)|go:""GO:0046661""(male sex differentiation)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR046357|interpro:IPR050754|mint:Q02790|rcsb pdb:1N1A|rcsb pdb:1P5Q|rcsb pdb:1Q1C|rcsb pdb:1QZ2|rcsb pdb:4DRJ|rcsb pdb:4LAV|rcsb pdb:4LAW|rcsb pdb:4LAX|rcsb pdb:4LAY|rcsb pdb:4TW8|rcsb pdb:6RCY|rcsb pdb:8FFV|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|dip:DIP-50866N|panther:PTHR10516(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:N0vDRDgcQ2x8xiWKdX9Zt+cHcsQ9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P04844	intact:EBI-27055664	intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530.6|ensembl:ENSP00000517679.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001129243.1|refseq:NP_002942.2|refseq:NP_001311235.1|refseq:NP_001311234.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1|ensembl:ENSG00000118705.18(gene)|ensembl:ENSG00000291973.1(gene)|ensembl:ENST00000237530.11(transcript)|ensembl:ENST00000709412.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0036211""(protein modification process)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|panther:PTHR12640(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q8NDI1	intact:EBI-27055664	intact:EBI-2689720|uniprotkb:Q9NWI9|uniprotkb:Q6QNV2|uniprotkb:Q6NX72|uniprotkb:Q53TV6|uniprotkb:Q6PIT3|uniprotkb:Q53TG7|uniprotkb:Q580X2|uniprotkb:O94977|ensembl:ENSP00000263991.5	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ehbp1_human(display_long)|uniprotkb:KIAA0903(gene name synonym)|uniprotkb:NACSIN(gene name synonym)|uniprotkb:EHBP1(gene name)|psi-mi:EHBP1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:XP_011531015.1|refseq:XP_011531016.1|refseq:XP_011531017.1|refseq:NP_001136086.1|refseq:NP_001136087.1|refseq:NP_001136088.1|refseq:NP_056067.2|refseq:XP_016859136.1|refseq:XP_016859137.1|refseq:XP_016859138.1|refseq:XP_005264282.1|refseq:XP_005264283.1|refseq:XP_005264284.1|rcsb pdb:6ZSJ|ensembl:ENSG00000115504.15(gene)|ensembl:ENST00000263991.9(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0015031""(protein transport)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR019448|interpro:IPR022735|interpro:IPR036872|interpro:IPR050540|mint:Q8NDI1|rcsb pdb:2D89|rcsb pdb:6ZSH|rcsb pdb:6ZSI|refseq:XP_016859132.1|refseq:XP_016859133.1|refseq:XP_016859140.1|panther:PTHR23167(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:sDcegXBYi8eQp7KReaysxBy3Ogc9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q9UHA4	intact:EBI-27055664	intact:EBI-1038192|uniprotkb:Q9H364|uniprotkb:J3KMX4|uniprotkb:B2R4A1|ensembl:ENSP00000424183.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ltor3_human(display_long)|uniprotkb:MAP2K1IP1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase 1-interacting protein 1(gene name synonym)|uniprotkb:LAMTOR3(gene name)|psi-mi:LAMTOR3(display_short)|uniprotkb:PRO2783(orf name)|uniprotkb:MEK-binding partner 1(gene name synonym)|uniprotkb:MAPKSP1(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase scaffold protein 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_068805.1|refseq:NP_001230665.1|ensembl:ENSG00000109270.13(gene)|ensembl:ENST00000499666.7(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008104""(protein localization)|go:""GO:0010008""(endosome membrane)|go:""GO:0019209""(kinase activator activity)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0035579""(specific granule membrane)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071986""(Ragulator complex)|go:""GO:1902414""(protein localization to cell junction)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990877""(FNIP-folliculin RagC/D GAP)|interpro:IPR015019(Mitogen-activated protein kinase kinase 1 interacting)|mint:Q9UHA4|rcsb pdb:1SKO|rcsb pdb:2ZL1|rcsb pdb:3CPT|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6B9X|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|rcsb pdb:6WJ2|rcsb pdb:6WJ3|rcsb pdb:7T3A|rcsb pdb:7T3B|rcsb pdb:7T3C|rcsb pdb:7UX2|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8DHB|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-8943724|reactome:R-HSA-9639288|panther:PTHR13378(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:0QvFsMOMU2EZyUVVVUqBij+gsKw9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q15907	intact:EBI-27055664	intact:EBI-722234|uniprotkb:Q2YDT2|uniprotkb:Q8NI07|uniprotkb:B2R7I4|uniprotkb:D6W671|uniprotkb:A5YM50|uniprotkb:Q5U0I1|uniprotkb:Q6FHR0|uniprotkb:Q6FI42|uniprotkb:B4DMK0|ensembl:ENSP00000333547.5	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:rb11b_human(display_long)|uniprotkb:GTP-binding protein YPT3(gene name synonym)|uniprotkb:RAB11B(gene name)|psi-mi:RAB11B(display_short)|uniprotkb:YPT3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_004209.2|ensembl:ENSG00000185236.12(gene)|ensembl:ENST00000328024.11(transcript)|go:""GO:0001881""(receptor recycling)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0019003""(GDP binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031489""(myosin V binding)|go:""GO:0032402""(melanosome transport)|go:""GO:0032456""(endocytic recycling)|go:""GO:0033572""(transferrin transport)|go:""GO:0035773""(insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0044070""(regulation of monoatomic anion transport)|go:""GO:0045054""(constitutive secretory pathway)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071468""(cellular response to acidic pH)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:2000008""(regulation of protein localization to cell surface)|go:""GO:2001135""(regulation of endocytic recycling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050209|mint:Q15907|rcsb pdb:2F9L|rcsb pdb:2F9M|rcsb pdb:4OJK|reactome:R-HSA-8854214|reactome:R-HSA-8873719|dip:DIP-50898N|panther:PTHR47979(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:+fsu7NPmd5fgoe0TE67IcISlscA9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O15126	intact:EBI-27055664	intact:EBI-954338|uniprotkb:O43587|uniprotkb:Q96BX1|uniprotkb:Q96QK5|uniprotkb:Q6FG23|ensembl:ENSP00000481022.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:scam1_human(display_long)|uniprotkb:SCAMP1(gene name)|psi-mi:SCAMP1(display_short)|uniprotkb:SCAMP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_004857.4|refseq:NP_001277158.1|ensembl:ENSG00000085365.18(gene)|ensembl:ENST00000621999.5(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0055038""(recycling endosome membrane)|interpro:IPR007273(SCAMP)|mint:O15126|reactome:R-HSA-6798695|panther:PTHR10687(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:Utuf4fnpMHS2yG4zfccdB2enfxI9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q9Y2Q5	intact:EBI-27055664	intact:EBI-2643704|uniprotkb:Q5VY99|uniprotkb:Q5VY97|uniprotkb:Q5VY98|ensembl:ENSP00000357288.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ltor2_human(display_long)|uniprotkb:LAMTOR2(gene name)|psi-mi:LAMTOR2(display_short)|uniprotkb:MAPBPIP(gene name synonym)|uniprotkb:Late endosomal/lysosomal Mp1-interacting protein(gene name synonym)|uniprotkb:Roadblock domain-containing protein 3(gene name synonym)|uniprotkb:Endosomal adaptor protein p14(gene name synonym)|uniprotkb:HSPC003(orf name)|uniprotkb:ROBLD3(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2(gene name synonym)|uniprotkb:Mitogen-activated protein-binding protein-interacting protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"dip:DIP-57000N|efo:""Orphanet:90023""|go:""GO:0070821""(tertiary granule membrane)|ensembl:ENSG00000116586.12(gene)|ensembl:ENST00000368305.9(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0008104""(protein localization)|go:""GO:0010008""(endosome membrane)|go:""GO:0010761""(fibroblast migration)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0035579""(specific granule membrane)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071986""(Ragulator complex)|go:""GO:0150116""(regulation of cell-substrate junction organization)|go:""GO:1902414""(protein localization to cell junction)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990877""(FNIP-folliculin RagC/D GAP)|interpro:IPR004942(Dynein light chain-related)|interpro:IPR037587|mint:Q9Y2Q5|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6B9X|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|rcsb pdb:6WJ2|rcsb pdb:6WJ3|rcsb pdb:7T3A|rcsb pdb:7T3B|rcsb pdb:7T3C|rcsb pdb:7UX2|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8DHB|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-8943724|reactome:R-HSA-9639288|refseq:NP_001138736.1|refseq:NP_054736.1|panther:PTHR13323(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:3durREyQgqI8N4q7RMVh9drah3s9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q15084	intact:EBI-27055664	intact:EBI-1043087|uniprotkb:Q6ZSH5|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7|ensembl:ENSP00000272227.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|refseq:NP_005733.1|ensembl:ENSG00000143870.13(gene)|ensembl:ENST00000272227.8(transcript)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006457""(protein folding)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0070062""(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|rcsb pdb:8CPQ|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|panther:PTHR45815(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q01844	intact:EBI-27055664	intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|uniprotkb:B0QYK1|uniprotkb:Q96MN4|ensembl:ENSP00000381031.2|intact:EBI-28987207|intact:EBI-10985407	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"efo:""Orphanet:209916""|efo:""Orphanet:319""|efo:""Orphanet:370334""|efo:""Orphanet:83469""|efo:""Orphanet:97338""|ensembl:ENSG00000182944.18(gene)|ensembl:ENST00000397938.7(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|refseq:NP_001156757.1|refseq:NP_001156758.1|refseq:NP_001156759.1|refseq:NP_005234.1|refseq:NP_053733.2|dip:DIP-34449N|panther:PTHR23238(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P50454	intact:EBI-27055664	intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|intact:EBI-25629313|ensembl:ENSP00000350894.4|ensembl:ENSP00000434412.1|ensembl:ENSP00000434657.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000149257.16(gene)|ensembl:ENST00000358171.8(transcript)|ensembl:ENST00000524558.5(transcript)|ensembl:ENST00000533603.5(transcript)|go:""GO:0003433""(chondrocyte development involved in endochondral bone morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0032964""(collagen biosynthetic process)|go:""GO:0045121""(membrane raft)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051604""(protein maturation)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|refseq:NP_001193943.1|refseq:NP_001226.2|refseq:XP_011543629.1|efo:""Orphanet:216812""|panther:PTHR11461(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P11586	intact:EBI-27055664	intact:EBI-709638|uniprotkb:Q86VC9|uniprotkb:Q9BVP5|uniprotkb:B2R5Y2|uniprotkb:G3V2B8|ensembl:ENSP00000498336.1|ensembl:ENSP00000498511.1|intact:EBI-21358459|uniprotkb:A0A024R652|uniprotkb:A0A384N5Y3	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:c1tc_human(display_long)|uniprotkb:MTHFD1(gene name)|psi-mi:MTHFD1(display_short)|uniprotkb:MTHFC(gene name synonym)|uniprotkb:MTHFD(gene name synonym)|uniprotkb:Epididymis secretory sperm binding protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"efo:""Orphanet:658813""|dip:DIP-33682N|ensembl:ENSG00000100714.18(gene)|ensembl:ENST00000651537.1(transcript)|ensembl:ENST00000652337.1(transcript)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001843""(neural tube closure)|go:""GO:0004329""(formate-tetrahydrofolate ligase activity)|go:""GO:0004477""(methenyltetrahydrofolate cyclohydrolase activity)|go:""GO:0004486""(""methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity"")|go:""GO:0004487""(""methylenetetrahydrofolate dehydrogenase (NAD+) activity"")|go:""GO:0004488""(""methylenetetrahydrofolate dehydrogenase (NADP+) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006555""(methionine metabolic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0007507""(heart development)|go:""GO:0009069""(serine family amino acid metabolic process)|go:""GO:0009070""(serine family amino acid biosynthetic process)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0009152""(purine ribonucleotide biosynthetic process)|go:""GO:0009257""(10-formyltetrahydrofolate biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019346""(transsulfuration)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0048702""(embryonic neurocranium morphogenesis)|go:""GO:0048703""(embryonic viscerocranium morphogenesis)|go:""GO:0061053""(somite development)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR020867|interpro:IPR027417|interpro:IPR036291|interpro:IPR046346|mint:P11586|rcsb pdb:1A4I|rcsb pdb:1DIA|rcsb pdb:1DIB|rcsb pdb:1DIG|rcsb pdb:6ECP|rcsb pdb:6ECQ|rcsb pdb:6ECR|reactome:R-HSA-196757|refseq:NP_005947.3|panther:PTHR48099(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:6ZizfpjVcaL5WNxKXL7qJpw59PI9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q16543	intact:EBI-27055664	intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005.1|intact:EBI-21355356	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_008996.1|ensembl:ENSG00000105401.10(gene)|ensembl:ENST00000222005.7(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006605""(protein targeting)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0060334""(regulation of type II interferon-mediated signaling pathway)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1990565""(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|rcsb pdb:7Z37|rcsb pdb:7Z38|rcsb pdb:7ZR0|rcsb pdb:7ZR5|rcsb pdb:7ZR6|rcsb pdb:8GAE|rcsb pdb:8GFT|rcsb pdb:8U1L|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|dip:DIP-27560N|panther:PTHR12800(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:iajhitd2iEmd17KfpU/nMaKc4049606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P29966	intact:EBI-27055664	intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_002347.5|ensembl:ENSG00000277443.3(gene)|ensembl:ENST00000612661.2(transcript)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006915""(apoptotic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007015""(actin filament organization)|go:""GO:0007417""(central nervous system development)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0021915""(neural tube development)|go:""GO:0022008""(neurogenesis)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042585""(germinal vesicle)|go:""GO:0042802""(identical protein binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997|panther:PTHR14353(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q96AG4	intact:EBI-27055664	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|uniprotkb:B2RE83|ensembl:ENSP00000225972.7	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_060979.2|ensembl:ENSG00000108829.10(gene)|ensembl:ENST00000225972.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045296""(cadherin binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050216|mint:Q96AG4|panther:PTHR45752(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P12236	intact:EBI-27055664	intact:EBI-356254|uniprotkb:Q96C49|ensembl:ENSP00000370808.5|ensembl:ENSP00000518609.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001627.2|ensembl:ENSG00000169100.14(gene)|ensembl:ENSG00000292334.1(gene)|ensembl:ENST00000381401.11(transcript)|ensembl:ENST00000711214.1(transcript)|go:""GO:0005471""(""ATP:ADP antiporter activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005744""(TIM23 mitochondrial import inner membrane translocase complex)|go:""GO:0006915""(apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0140021""(mitochondrial ADP transmembrane transport)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1990544""(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|reactome:R-HSA-9837999|panther:PTHR45635(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P50225	intact:EBI-27055664	intact:EBI-2814403|uniprotkb:Q9UGG7|uniprotkb:Q9BVU6|uniprotkb:Q92818|uniprotkb:Q86U58|uniprotkb:Q2NL71|ensembl:ENSP00000321988.7|ensembl:ENSP00000457912.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:st1a1_human(display_long)|uniprotkb:SULT1A1(gene name)|psi-mi:SULT1A1(display_short)|uniprotkb:STP(gene name synonym)|uniprotkb:STP1(gene name synonym)|uniprotkb:Aryl sulfotransferase 1(gene name synonym)|uniprotkb:HAST1/HAST2(gene name synonym)|uniprotkb:Phenol sulfotransferase 1(gene name synonym)|uniprotkb:Phenol-sulfating phenol sulfotransferase 1(gene name synonym)|uniprotkb:ST1A3(gene name synonym)|uniprotkb:Thermostable phenol sulfotransferase(gene name synonym)|uniprotkb:OK/SW-cl.88(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001046.2|refseq:NP_803565.1|refseq:NP_803566.1|refseq:NP_803878.1|refseq:NP_803880.1|ensembl:ENSG00000196502.15(gene)|ensembl:ENST00000314752.12(transcript)|ensembl:ENST00000569554.5(transcript)|go:""GO:0004062""(aryl sulfotransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006068""(ethanol catabolic process)|go:""GO:0006584""(catecholamine metabolic process)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0008146""(sulfotransferase activity)|go:""GO:0008210""(estrogen metabolic process)|go:""GO:0009308""(amine metabolic process)|go:""GO:0009812""(flavonoid metabolic process)|go:""GO:0047894""(flavonol 3-sulfotransferase activity)|go:""GO:0050294""(steroid sulfotransferase activity)|go:""GO:0050427""(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|go:""GO:0050656""(3'-phosphoadenosine 5'-phosphosulfate binding)|go:""GO:0051923""(sulfation)|interpro:IPR000863(Sulphotransferase)|interpro:IPR027417|mint:P50225|rcsb pdb:1LS6|rcsb pdb:1Z28|rcsb pdb:2D06|rcsb pdb:3QVU|rcsb pdb:3QVV|rcsb pdb:3U3J|rcsb pdb:3U3K|rcsb pdb:3U3M|rcsb pdb:3U3O|rcsb pdb:3U3R|rcsb pdb:4GRA|reactome:R-HSA-156584|reactome:R-HSA-9753281|refseq:XP_016879102.1|refseq:XP_016879095.1|refseq:XP_016879100.1|refseq:XP_016879101.1|panther:PTHR11783(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:FweXcoVwTFvo9HJhsoiXfxx2nbo9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P05023	intact:EBI-27055664	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|ensembl:ENSP00000295598.5|intact:EBI-10963133	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"panther:PTHR43294(orthology-group)|ensembl:ENSG00000163399.16(gene)|ensembl:ENST00000295598.10(transcript)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0005391""(""P-type sodium:potassium-exchanging transporter activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0007231""(osmosensory signaling pathway)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016791""(phosphatase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030315""(T-tubule)|go:""GO:0030424""(axon)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031090""(organelle membrane)|go:""GO:0031402""(sodium ion binding)|go:""GO:0031947""(negative regulation of glucocorticoid biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0045823""(positive regulation of heart contraction)|go:""GO:0045989""(positive regulation of striated muscle contraction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060342""(photoreceptor inner segment membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086009""(membrane repolarization)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903416""(response to glycoside)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990239""(steroid hormone binding)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|interpro:IPR050510|mint:P05023|rcsb pdb:7E1Z|rcsb pdb:7E20|rcsb pdb:7E21|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|efo:""Orphanet:521414""|efo:""Orphanet:564178"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P53007	intact:EBI-27055664	intact:EBI-359163|uniprotkb:Q9BSK6|uniprotkb:A8K8E8|ensembl:ENSP00000215882.5	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:txtp_human(display_long)|uniprotkb:SLC25A1(gene name)|psi-mi:SLC25A1(display_short)|uniprotkb:SLC20A3(gene name synonym)|uniprotkb:Citrate transport protein(gene name synonym)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 1(gene name synonym)|uniprotkb:Mitochondrial citrate carrier(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"efo:""Orphanet:356978""|efo:""Orphanet:98914""|ensembl:ENSG00000100075.10(gene)|ensembl:ENST00000215882.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006843""(mitochondrial citrate transmembrane transport)|go:""GO:0015137""(citrate transmembrane transporter activity)|go:""GO:0015142""(tricarboxylic acid transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071913""(citrate secondary active transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|interpro:IPR049563|mint:P53007|reactome:R-HSA-428643|refseq:NP_005975.1|panther:PTHR45788(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:MB0RrMAQme4F8M4IivU1AqUxlgA9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P80723	intact:EBI-27055664	intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281.3|ensembl:ENSP00000482066.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788.9(gene)|ensembl:ENST00000322611.4(transcript)|ensembl:ENST00000616743.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0007356""(thorax and anterior abdomen determination)|go:""GO:0008406""(gonad development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016605""(PML body)|go:""GO:0016607""(nuclear speck)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030054""(cell junction)|go:""GO:0030426""(growth cone)|go:""GO:0031982""(vesicle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0060231""(mesenchymal to epithelial transition)|go:""GO:0060421""(positive regulation of heart growth)|go:""GO:0060539""(diaphragm development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072075""(metanephric mesenchyme development)|go:""GO:0072112""(podocyte differentiation)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:2001076""(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034|panther:PTHR23212(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:X+L20HKimV3J+vLnQljg+x78+e09606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q14126	intact:EBI-27055664	intact:EBI-2556545|uniprotkb:Q4KKU6|ensembl:ENSP00000261590.8	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:dsg2_human(display_long)|uniprotkb:CDHF5(gene name synonym)|uniprotkb:HDGC(gene name synonym)|uniprotkb:Cadherin family member 5(gene name synonym)|uniprotkb:DSG2(gene name)|psi-mi:DSG2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"dip:DIP-46250N|efo:""Orphanet:154""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|ensembl:ENSG00000046604.15(gene)|ensembl:ENST00000261590.13(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0002934""(desmosome organization)|go:""GO:0003165""(Purkinje myocyte development)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0009986""(cell surface)|go:""GO:0014704""(intercalated disc)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0030054""(cell junction)|go:""GO:0030057""(desmosome)|go:""GO:0032570""(response to progesterone)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0086073""(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:""GO:0086083""(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR050971|mint:Q14126|rcsb pdb:2YQG|rcsb pdb:5ERD|rcsb pdb:5J5J|rcsb pdb:6QNT|rcsb pdb:6QNU|rcsb pdb:6SIT|rcsb pdb:7A7D|rcsb pdb:7AGF|rcsb pdb:7AGG|rcsb pdb:8QJX|rcsb pdb:8QJY|rcsb pdb:8QK3|reactome:R-HSA-351906|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:NP_001934.2|panther:PTHR24025(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:LCSf84WRgh5lTrze5IEzFaBeuEc9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q99714	intact:EBI-27055664	intact:EBI-79964|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9|ensembl:ENSP00000168216.6	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	"psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:""3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))""(gene name synonym)|uniprotkb:""3alpha(or 20beta)-hydroxysteroid dehydrogenase""(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"panther:PTHR43658(orthology-group)|efo:""Orphanet:391428""|efo:""Orphanet:391457""|efo:""Orphanet:85295""|ensembl:ENSG00000072506.14(gene)|ensembl:ENST00000168216.11(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003857""(3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0004303""(""estradiol 17-beta-dehydrogenase [NAD(P)+] activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005886""(plasma membrane)|go:""GO:0006550""(isoleucine catabolic process)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008207""(C21-steroid hormone metabolic process)|go:""GO:0008209""(androgen metabolic process)|go:""GO:0008210""(estrogen metabolic process)|go:""GO:0008709""(""cholate 7-alpha-dehydrogenase (NAD+) activity"")|go:""GO:0030283""(""testosterone dehydrogenase [NAD(P)+] activity"")|go:""GO:0030678""(mitochondrial ribonuclease P complex)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0043527""(tRNA methyltransferase complex)|go:""GO:0044594""(""17-beta-hydroxysteroid dehydrogenase (NAD+) activity"")|go:""GO:0047015""(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:""GO:0047035""(""testosterone dehydrogenase (NAD+) activity"")|go:""GO:0047044""(""androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity"")|go:""GO:0051289""(protein homotetramerization)|go:""GO:0062173""(brexanolone metabolic process)|go:""GO:0070901""(mitochondrial tRNA methylation)|go:""GO:0097745""(mitochondrial tRNA 5'-end processing)|go:""GO:0106281""(""chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity"")|go:""GO:0106282""(""isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity"")|go:""GO:0106283""(""ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity"")|go:""GO:1990180""(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1SO8|rcsb pdb:1U7T|rcsb pdb:2O23|rcsb pdb:7ONU|rcsb pdb:8CBK|rcsb pdb:8CBL|rcsb pdb:8CBM|rcsb pdb:8CBO|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|reactome:R-HSA-9837999|refseq:NP_001032900.1|refseq:NP_004484.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q8TEV9	intact:EBI-27055664	intact:EBI-2961718|uniprotkb:A5PKZ5|uniprotkb:Q3ZCN0|uniprotkb:Q6PJL3|ensembl:ENSP00000385025.3|ensembl:ENSP00000492062.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:smcr8_human(display_long)|uniprotkb:SMCR8(gene name)|psi-mi:SMCR8(display_short)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 8 protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_658988.2|ensembl:ENSG00000176994.11(gene)|ensembl:ENSG00000283741.2(gene)|ensembl:ENST00000406438.5(transcript)|ensembl:ENST00000639332.2(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006914""(autophagy)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0019901""(protein kinase binding)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0032045""(guanyl-nucleotide exchange factor complex)|go:""GO:0042995""(cell projection)|go:""GO:0045920""(negative regulation of exocytosis)|go:""GO:0050777""(negative regulation of immune response)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:1901098""(positive regulation of autophagosome maturation)|go:""GO:1902902""(negative regulation of autophagosome assembly)|go:""GO:1903432""(regulation of TORC1 signaling)|go:""GO:1990316""(Atg1/ULK1 kinase complex)|interpro:IPR037520|interpro:IPR037521|mint:Q8TEV9|rcsb pdb:6LT0|rcsb pdb:6V4U|rcsb pdb:7EL6|rcsb pdb:7MGE|rcsb pdb:7O2W|panther:PTHR31334(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:w+qVoh0JXrz6HImAj8sYNYGklBg9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P54577	intact:EBI-27055664	intact:EBI-1048893|uniprotkb:O43276|uniprotkb:Q53EN1|uniprotkb:B3KWK4|uniprotkb:D3DPQ4|ensembl:ENSP00000362576.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:syyc_human(display_long)|uniprotkb:YARS1(gene name)|psi-mi:YARS1(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:YARS(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000134684.13(gene)|ensembl:ENST00000373477.9(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004831""(tyrosine-tRNA ligase activity)|go:""GO:0005153""(interleukin-8 receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006437""(tyrosyl-tRNA aminoacylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0016604""(nuclear body)|go:""GO:0036094""(small molecule binding)|go:""GO:0042594""(response to starvation)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR051270|mint:P54577|rcsb pdb:1N3L|rcsb pdb:1NTG|rcsb pdb:1Q11|rcsb pdb:4Q93|rcsb pdb:4QBT|rcsb pdb:5THH|rcsb pdb:5THL|rcsb pdb:7ROU|reactome:R-HSA-379716|refseq:NP_003671.1|dip:DIP-50415N|efo:""Orphanet:100045""|panther:PTHR11586(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:y/0Qs8iOgW5w5LVLWnCvowVpEu89606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P05455	intact:EBI-27055664	intact:EBI-358037|uniprotkb:Q15367|uniprotkb:Q53XJ4|ensembl:ENSP00000260956.4|ensembl:ENSP00000386636.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"panther:PTHR22792(orthology-group)|refseq:NP_003133.1|ensembl:ENSG00000138385.16(gene)|ensembl:ENST00000260956.9(transcript)|ensembl:ENST00000409333.1(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0001682""(tRNA 5'-leader removal)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006400""(tRNA modification)|go:""GO:0006409""(tRNA export from nucleus)|go:""GO:0008033""(tRNA processing)|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008334""(histone mRNA metabolic process)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0042780""(tRNA 3'-end processing)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0071045""(nuclear histone mRNA catabolic process)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1990825""(sequence-specific mRNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476|refseq:NP_001281074.1|dip:DIP-29750N"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q9UHD1	intact:EBI-27055664	intact:EBI-2550959|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49|ensembl:ENSP00000319255.6|ensembl:ENSP00000496744.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001137545.1|refseq:NP_036256.2|ensembl:ENSG00000110172.12(gene)|ensembl:ENSG00000285023.2(gene)|ensembl:ENST00000320585.11(transcript)|ensembl:ENST00000646618.2(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0043531""(ADP binding)|go:""GO:0051298""(centrosome duplication)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:1900034""(regulation of cellular response to heat)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|mint:Q9UHD1|rcsb pdb:2YRT|panther:PTHR12621(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P61106	intact:EBI-27055664	intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946.4|ensembl:ENSP00000515613.1|ensembl:ENSP00000515614.1|intact:EBI-21352994	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055978|imex:IM-29147-7	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_057406.2|ensembl:ENSG00000119396.12(gene)|ensembl:ENST00000373840.9(transcript)|ensembl:ENST00000703999.1(transcript)|ensembl:ENST00000704000.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001845""(phagolysosome assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005795""(Golgi stack)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019003""(GDP binding)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0031489""(myosin V binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0042175""(nuclear outer membrane-endoplasmic reticulum membrane network)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090382""(phagosome maturation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|interpro:IPR050209|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606	intact-crc:DF34FC0A9E82F93D|rigid:Z4aOkwcgxrgDqw8RXCHLmoQ4NNk	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P42166	intact:EBI-10726196	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_003267.1|ensembl:ENSG00000120802.15(gene)|ensembl:ENST00000266732.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0045296""(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|interpro:IPR051656|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F|rcsb pdb:8FN7|rcsb pdb:8FND|rcsb pdb:8FNG|rcsb pdb:8FNH|rcsb pdb:8FNJ|rcsb pdb:8FNL|rcsb pdb:8FNM|rcsb pdb:8FNN|rcsb pdb:8FNO|rcsb pdb:8FNP|rcsb pdb:8FNQ|panther:PTHR12019(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9BSJ8	intact:EBI-10726196	intact:EBI-355956|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548|ensembl:ENSP00000377612.5|intact:EBI-21360363	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001171725.1|refseq:NP_056107.1|ensembl:ENSG00000139641.13(gene)|ensembl:ENST00000394048.10(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0008429""(phosphatidylethanolamine binding)|go:""GO:0016020""(membrane)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:0120014""(phospholipid transfer activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|interpro:IPR051634|mint:Q9BSJ8|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9845576|dip:DIP-57197N|panther:PTHR45761(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q14739	intact:EBI-10726196	intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163.4|ensembl:ENSP00000339883.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	"psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:""3-beta-hydroxysterol Delta (14)-reductase""(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:1426""|efo:""Orphanet:448267""|efo:""Orphanet:779""|dip:DIP-5987N|ensembl:ENSG00000143815.15(gene)|ensembl:ENST00000272163.9(transcript)|ensembl:ENST00000338179.6(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0030223""(neutrophil differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0050613""(Delta14-sterol reductase activity)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0070087""(chromo shadow domain binding)|go:""GO:0070402""(NADPH binding)|go:""GO:0140463""(chromatin-protein adaptor activity)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|panther:PTHR21257(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O15173	intact:EBI-10726196	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425.4|ensembl:ENSP00000429301.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_006311.2|ensembl:ENSG00000164040.18(gene)|ensembl:ENST00000296425.10(transcript)|ensembl:ENST00000520121.6(transcript)|go:""GO:0003707""(nuclear steroid receptor activity)|go:""GO:0005496""(steroid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0012505""(endomembrane system)|go:""GO:0015232""(heme transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0060612""(adipose tissue development)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|interpro:IPR050577|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9707616|panther:PTHR10281(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9Y2U8	intact:EBI-10726196	intact:EBI-2561428|uniprotkb:Q9NT47|uniprotkb:Q9NYA5|ensembl:ENSP00000308369.2|intact:EBI-40264392	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:man1_human(display_long)|uniprotkb:MAN1(gene name synonym)|uniprotkb:LEM domain-containing protein 3(gene name synonym)|uniprotkb:LEMD3(gene name)|psi-mi:LEMD3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000174106.3(gene)|ensembl:ENST00000308330.3(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0016020""(membrane)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032926""(negative regulation of activin receptor signaling pathway)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018996|interpro:IPR034394|interpro:IPR035979|interpro:IPR041885|interpro:IPR052277|mint:Q9Y2U8|rcsb pdb:2CH0|rcsb pdb:5ZOJ|rcsb pdb:5ZOK|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001161086.1|refseq:NP_055134.2|efo:""Orphanet:166119""|efo:""Orphanet:1879""|efo:""Orphanet:94063""|panther:PTHR48036(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:8AILzxAZLbxCAzlJ7oPg9WybOmY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q07065	intact:EBI-10726196	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265.4|intact:EBI-21353377	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_006816.2|ensembl:ENSG00000136026.14(gene)|ensembl:ENST00000378026.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005811""(lipid droplet)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042599""(lamellar body)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270|panther:PTHR45161(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P28288	intact:EBI-10726196	intact:EBI-80992|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|ensembl:ENSP00000359233.4|uniprotkb:D3DT46	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001116146.1|refseq:NP_002849.1|ensembl:ENSG00000117528.14(gene)|ensembl:ENST00000370214.9(transcript)|go:""GO:0000038""(very long-chain fatty acid metabolic process)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0007031""(peroxisome organization)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0015910""(long-chain fatty acid import into peroxisome)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0042760""(very long-chain fatty acid catabolic process)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0047617""(fatty acyl-CoA hydrolase activity)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:1903512""(phytanic acid metabolic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR050835|mint:P28288|rcsb pdb:8Z0F|rcsb pdb:8Z9X|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798|panther:PTHR11384(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P04843	intact:EBI-10726196	intact:EBI-355963|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0|ensembl:ENSP00000296255.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:402020""|ensembl:ENSG00000163902.12(gene)|ensembl:ENST00000296255.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0042470""(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_002941.1|dip:DIP-38152N|panther:PTHR21049(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O95573	intact:EBI-10726196	intact:EBI-1190822|uniprotkb:Q60I92|uniprotkb:Q8IUM9|intact:EBI-21359981|ensembl:ENSP00000350012.3|ensembl:ENSP00000375918.3|ensembl:ENSP00000504861.1|ensembl:ENSP00000504907.1|ensembl:ENSP00000505400.1|ensembl:ENSP00000505654.1|ensembl:ENSP00000505793.1|ensembl:ENSP00000505856.1|ensembl:ENSP00000505940.1|ensembl:ENSP00000506361.1|ensembl:ENSP00000506468.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:acsl3_human(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:ACSL3(gene name)|psi-mi:ACSL3(display_short)|uniprotkb:ACS3(gene name synonym)|uniprotkb:FACL3(gene name synonym)|uniprotkb:LACS3(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase 3(gene name synonym)|uniprotkb:Medium-chain acyl-CoA ligase Acsl3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_004448.2|refseq:NP_976251.1|refseq:XP_016859073.1|panther:PTHR43272(orthology-group)|ensembl:ENSG00000123983.15(gene)|ensembl:ENST00000357430.8(transcript)|ensembl:ENST00000392066.7(transcript)|ensembl:ENST00000679514.1(transcript)|ensembl:ENST00000679558.1(transcript)|ensembl:ENST00000680147.1(transcript)|ensembl:ENST00000680251.1(transcript)|ensembl:ENST00000680395.1(transcript)|ensembl:ENST00000680684.1(transcript)|ensembl:ENST00000680921.1(transcript)|ensembl:ENST00000681383.1(transcript)|ensembl:ENST00000681697.1(transcript)|go:""GO:0001676""(long-chain fatty acid metabolic process)|go:""GO:0004467""(long-chain fatty acid-CoA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0031956""(medium-chain fatty acid-CoA ligase activity)|go:""GO:0034379""(very-low-density lipoprotein particle assembly)|go:""GO:0035336""(long-chain fatty-acyl-CoA metabolic process)|go:""GO:0035338""(long-chain fatty-acyl-CoA biosynthetic process)|go:""GO:0042998""(positive regulation of Golgi to plasma membrane protein transport)|go:""GO:0044539""(long-chain fatty acid import into cell)|go:""GO:0047676""(arachidonate-CoA ligase activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051047""(positive regulation of secretion)|go:""GO:0090433""(palmitoyl-CoA ligase activity)|go:""GO:2001247""(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR042099|mint:O95573|reactome:R-HSA-434313|reactome:R-HSA-75876"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:L5tCBPOlL45uh0aUFi4algZQ5nY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P49257	intact:EBI-10726196	intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047.4|intact:EBI-21355115	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000074695.6(gene)|ensembl:ENST00000251047.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006457""(protein folding)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007596""(blood coagulation)|go:""GO:0010638""(positive regulation of organelle organization)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0030017""(sarcomere)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903215""(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR051136|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|rcsb pdb:8JP4|rcsb pdb:8JP5|rcsb pdb:8JP6|rcsb pdb:8JP7|rcsb pdb:8JP8|rcsb pdb:8JP9|rcsb pdb:8JPG|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-948021|refseq:NP_005561.1|efo:""Orphanet:35909""|dip:DIP-42188N|panther:PTHR12223(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P30519	intact:EBI-10726196	intact:EBI-712096|uniprotkb:I3L430|uniprotkb:O60605|uniprotkb:A8MT35|uniprotkb:D3DUD5|ensembl:ENSP00000219700.6|ensembl:ENSP00000381595.3|ensembl:ENSP00000385100.2|ensembl:ENSP00000391637.1|ensembl:ENSP00000394103.3|ensembl:ENSP00000459214.1|ensembl:ENSP00000478785.1|ensembl:ENSP00000481295.1|ensembl:ENSP00000481811.1|ensembl:ENSP00000483319.2|ensembl:ENSP00000484422.1|ensembl:ENSP00000484423.1|ensembl:ENSP00000484467.1|ensembl:ENSP00000487673.1|ensembl:ENSP00000488579.1|ensembl:ENSP00000488880.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:hmox2_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)|uniprotkb:HO2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001273196.1|refseq:NP_001273197.1|refseq:NP_001273198.1|refseq:NP_001273199.1|refseq:NP_001273200.1|refseq:NP_001120676.1|refseq:NP_001120677.1|refseq:NP_001120678.1|refseq:NP_002125.3|refseq:XP_016878685.1|refseq:XP_016878686.1|dip:DIP-53564N|ensembl:ENSG00000103415.12(gene)|ensembl:ENSG00000277424.4(gene)|ensembl:ENST00000219700.10(transcript)|ensembl:ENST00000398595.7(transcript)|ensembl:ENST00000406590.6(transcript)|ensembl:ENST00000414777.5(transcript)|ensembl:ENST00000458134.7(transcript)|ensembl:ENST00000570646.6(transcript)|ensembl:ENST00000612525.4(transcript)|ensembl:ENST00000615778.4(transcript)|ensembl:ENST00000619528.4(transcript)|ensembl:ENST00000619913.4(transcript)|ensembl:ENST00000620445.3(transcript)|ensembl:ENST00000621065.4(transcript)|ensembl:ENST00000622146.4(transcript)|ensembl:ENST00000631540.1(transcript)|ensembl:ENST00000631677.1(transcript)|ensembl:ENST00000632458.1(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0004392""(""heme oxygenase (decyclizing) activity"")|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006788""(heme oxidation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042167""(heme catabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:P30519|rcsb pdb:2Q32|rcsb pdb:2QPP|rcsb pdb:2RGZ|rcsb pdb:4WMH|rcsb pdb:5UC8|rcsb pdb:5UC9|rcsb pdb:5UCA|reactome:R-HSA-189483|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-917937|reactome:R-HSA-9707564|panther:PTHR10720(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:yTwXdEjnQgfiFBvl5fhcCwDOJWo9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P50402	intact:EBI-10726196	intact:EBI-489887|ensembl:ENSP00000358857.4|ensembl:ENSP00000507533.1|uniprotkb:Q6FI02	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000102119.12(gene)|ensembl:ENST00000369842.9(transcript)|ensembl:ENST00000683627.1(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006936""(muscle contraction)|go:""GO:0007517""(muscle organ development)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071763""(nuclear membrane organization)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0160045""(TMEM240-body)|go:""GO:1990000""(amyloid fibril formation)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|refseq:NP_000108.1|efo:""Orphanet:98863""|dip:DIP-34638N|panther:PTHR15171(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q5JTV8	intact:EBI-10726196	intact:EBI-2559665|ensembl:ENSP00000476687.1|uniprotkb:Q9H8Y6|uniprotkb:Q8IZ65|uniprotkb:Q5JTV6|uniprotkb:B0QZ57|uniprotkb:Q9Y3X5|uniprotkb:Q9HAJ1|uniprotkb:Q9NV52|uniprotkb:A8K630|intact:EBI-40264785|uniprotkb:A0A0A0MSK5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:toip1_human(display_long)|uniprotkb:TOR1AIP1(gene name)|psi-mi:TOR1AIP1(display_short)|uniprotkb:Lamin-associated protein 1B(gene name synonym)|uniprotkb:LAP1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000143337.19(gene)|ensembl:ENST00000606911.7(transcript)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0051117""(ATPase binding)|go:""GO:0071763""(nuclear membrane organization)|go:""GO:0090435""(protein localization to nuclear envelope)|interpro:IPR008662(Lamina-associated polypeptide 1C)|interpro:IPR038599|interpro:IPR046753|interpro:IPR046754|mint:Q5JTV8|rcsb pdb:4TVS|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_001254507.1|refseq:NP_056417.2|dip:DIP-56692N|efo:""Orphanet:424261""|panther:PTHR18843(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:qFH5HTm3fcIwmGL486H8IqZHG489606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O15498	intact:EBI-10726196	intact:EBI-4402903|uniprotkb:Q53F01|uniprotkb:Q6FGU9|uniprotkb:Q6IB15|uniprotkb:B4DR94|ensembl:ENSP00000223369.2|ensembl:ENSP00000504623.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ykt6_human(display_long)|uniprotkb:YKT6(gene name)|psi-mi:YKT6(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_006546.1|refseq:XP_016867171.1|ensembl:ENSG00000106636.9(gene)|ensembl:ENST00000223369.3(transcript)|ensembl:ENST00000679020.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006903""(vesicle targeting)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0030133""(transport vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045296""(cadherin binding)|go:""GO:0097440""(apical dendrite)|go:""GO:0097441""(basal dendrite)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR045848|mint:O15498|rcsb pdb:6J74|rcsb pdb:6J7F|rcsb pdb:6J7X|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9013423|panther:PTHR45806(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:pkTOoQ9XXEVYHKNvqOMCU6x4nZg9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q7Z2W4	intact:EBI-10726196	intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_064504.2|refseq:NP_078901.3|dip:DIP-37896N|ensembl:ENSG00000105939.14(gene)|ensembl:ENST00000242351.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0009615""(response to virus)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0061014""(positive regulation of mRNA catabolic process)|go:""GO:1900246""(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|interpro:IPR051712|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|rcsb pdb:7KZH|rcsb pdb:7TGQ|reactome:R-HSA-6802952|panther:PTHR45740(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O95292	intact:EBI-10726196	intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR10809(orthology-group)|dip:DIP-39816N|efo:""Orphanet:209335""|efo:""Orphanet:803""|ensembl:ENSG00000124164.16(gene)|ensembl:ENST00000475243.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019899""(enzyme binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0044830""(modulation by host of viral RNA genome replication)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046725""(negative regulation by virus of viral protein levels in host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0090114""(COPII-coated vesicle budding)|go:""GO:0090158""(endoplasmic reticulum membrane organization)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|refseq:NP_001182606.1|refseq:NP_004729.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P49411	intact:EBI-10726196	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:254925""|ensembl:ENSG00000178952.11(gene)|ensembl:ENST00000313511.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045202""(synapse)|go:""GO:0045471""(response to ethanol)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070125""(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|interpro:IPR050055|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|reactome:R-HSA-9754560|refseq:NP_003312.3|refseq:XP_016879108.1|panther:PTHR43721(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:gmW0HIoZ+8MccQHJ44Lcu2uwCss9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P18031	intact:EBI-10726196	intact:EBI-968788|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4|ensembl:ENSP00000360683.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N|ensembl:ENSG00000196396.10(gene)|ensembl:ENST00000371621.5(transcript)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0003723""(RNA binding)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0009968""(negative regulation of signal transduction)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030162""(regulation of proteolysis)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031904""(endosome lumen)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033157""(regulation of intracellular protein transport)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035791""(platelet-derived growth factor receptor-beta signaling pathway)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045296""(cadherin binding)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071732""(cellular response to nitric oxide)|go:""GO:0097443""(sorting endosome)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903896""(positive regulation of IRE1-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904753""(negative regulation of vascular associated smooth muscle cell migration)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990264""(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:""GO:2000353""(positive regulation of endothelial cell apoptotic process)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1AAX|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2F6Z|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:2NT7|rcsb pdb:2NTA|rcsb pdb:2QBP|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2QBS|rcsb pdb:2VEU|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2ZMM|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:3EB1|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QDV|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:6OMY|rcsb pdb:6PFW|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:6XE8|rcsb pdb:6XEF|rcsb pdb:6XEA|rcsb pdb:6XED|rcsb pdb:6XEE|rcsb pdb:6XEG|rcsb pdb:7FQM|rcsb pdb:7FQN|rcsb pdb:7FQO|rcsb pdb:7FQP|rcsb pdb:7FQQ|rcsb pdb:7FQR|rcsb pdb:7FQS|rcsb pdb:7FQT|rcsb pdb:7FQU|rcsb pdb:7FQV|rcsb pdb:7FQW|rcsb pdb:7FQX|rcsb pdb:7FQY|rcsb pdb:7FQZ|rcsb pdb:7FRE|rcsb pdb:7FRF|rcsb pdb:7FRG|rcsb pdb:7FRH|rcsb pdb:7FRI|rcsb pdb:7FRJ|rcsb pdb:7FRK|rcsb pdb:7FRL|rcsb pdb:7FRM|rcsb pdb:7FRN|rcsb pdb:7FRO|rcsb pdb:7FRP|rcsb pdb:7FRQ|rcsb pdb:7FRR|rcsb pdb:7FRS|rcsb pdb:7FRT|rcsb pdb:7FRU|rcsb pdb:7GS7|rcsb pdb:7GS8|rcsb pdb:7GS9|rcsb pdb:7GSA|rcsb pdb:7GSB|rcsb pdb:7GSC|rcsb pdb:7GSD|rcsb pdb:7GSE|rcsb pdb:7GSF|rcsb pdb:7GSG|rcsb pdb:7GSH|rcsb pdb:7GSI|rcsb pdb:7GSJ|rcsb pdb:7GSK|rcsb pdb:7GSL|rcsb pdb:7GSM|rcsb pdb:7GSN|rcsb pdb:7GSO|rcsb pdb:7GSQ|rcsb pdb:7GSR|rcsb pdb:7GST|rcsb pdb:7GSU|rcsb pdb:7GSV|rcsb pdb:7GSW|rcsb pdb:7GSX|rcsb pdb:7GSY|rcsb pdb:7GSZ|rcsb pdb:7GT0|rcsb pdb:7GT1|rcsb pdb:7GT2|rcsb pdb:7GT3|rcsb pdb:7GT4|rcsb pdb:7GT5|rcsb pdb:7GTI|rcsb pdb:7GT6|rcsb pdb:7GT7|rcsb pdb:7GT8|rcsb pdb:7GT9|rcsb pdb:7GTA|rcsb pdb:7GTB|rcsb pdb:7GTC|rcsb pdb:7GTD|rcsb pdb:7GTE|rcsb pdb:7GTF|rcsb pdb:7GTG|rcsb pdb:7GTH|rcsb pdb:7GTJ|rcsb pdb:7GTK|rcsb pdb:7GTL|rcsb pdb:7GTM|rcsb pdb:7GTN|rcsb pdb:7GTO|rcsb pdb:7GTP|rcsb pdb:7GTQ|rcsb pdb:7GTR|rcsb pdb:7GTS|rcsb pdb:7GTT|rcsb pdb:7GTU|rcsb pdb:7GTV|rcsb pdb:7GTW|rcsb pdb:7GTX|rcsb pdb:7GTY|rcsb pdb:7GTZ|rcsb pdb:7GU0|rcsb pdb:7GU1|rcsb pdb:7GU2|rcsb pdb:7GU3|rcsb pdb:7GU4|rcsb pdb:7GU5|rcsb pdb:7GU6|rcsb pdb:7GU7|rcsb pdb:7GU8|rcsb pdb:7GU9|rcsb pdb:7GUA|rcsb pdb:7GUB|rcsb pdb:7GUC|rcsb pdb:7KEN|rcsb pdb:7KEY|rcsb pdb:7KLX|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MKZ|rcsb pdb:7MM1|rcsb pdb:7MN7|rcsb pdb:7MN9|rcsb pdb:7MNA|rcsb pdb:7MNB|rcsb pdb:7MNC|rcsb pdb:7MND|rcsb pdb:7MNE|rcsb pdb:7MNF|rcsb pdb:7MOU|rcsb pdb:7MOV|rcsb pdb:7MOW|rcsb pdb:7RIN|rcsb pdb:7S4F|rcsb pdb:8DU7|rcsb pdb:8EXI|rcsb pdb:8EXJ|rcsb pdb:8EXK|rcsb pdb:8EXM|rcsb pdb:8EXN|rcsb pdb:8EYA|rcsb pdb:8EYB|rcsb pdb:8EYC|rcsb pdb:8F88|rcsb pdb:8G65|rcsb pdb:8G67|rcsb pdb:8G68|rcsb pdb:8G69|rcsb pdb:8G6A|rcsb pdb:8SKL|rcsb pdb:8U1E|rcsb pdb:8XOY|rcsb pdb:9C66|rcsb pdb:9CYO|rcsb pdb:9CYP|rcsb pdb:9CYQ|rcsb pdb:9CYR|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-77387|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-9860927|panther:PTHR46047(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9P0L0	intact:EBI-10726196	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_003565.4|refseq:NP_919415.2|ensembl:ENSG00000101558.14(gene)|ensembl:ENST00000400000.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031982""(vesicle)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035627""(ceramide transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0061025""(membrane fusion)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0090114""(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|dip:DIP-41135N|panther:PTHR10809(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8N766	intact:EBI-10726196	intact:EBI-1044442|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62|ensembl:ENSP00000420608.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:480898""|ensembl:ENSG00000127463.16(gene)|ensembl:ENST00000477853.6(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072546""(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|rcsb pdb:8EOI|rcsb pdb:8J0N|rcsb pdb:8J0O|rcsb pdb:8S9S|rcsb pdb:9C7V|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|refseq:NP_055862.1|panther:PTHR21573(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q86Y07	intact:EBI-10726196	intact:EBI-1207615|uniprotkb:Q49AK9|uniprotkb:Q53EU9|uniprotkb:Q86Y08|uniprotkb:Q86Y09|uniprotkb:Q86Y10|uniprotkb:Q86Y11|uniprotkb:Q86Y12|uniprotkb:Q8IXI5|uniprotkb:Q99987|uniprotkb:Q53S39|uniprotkb:Q53S77|uniprotkb:Q53TU1|uniprotkb:B4DKL0|uniprotkb:D6W5D4|uniprotkb:D6W5D6|ensembl:ENSP00000342381.4|ensembl:ENSP00000408002.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:vrk2_human(display_long)|uniprotkb:VRK2(gene name)|psi-mi:VRK2(display_short)|uniprotkb:Vaccinia-related kinase 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:XP_011531394.1|refseq:XP_006712153.1|refseq:XP_006712154.1|refseq:XP_006712155.1|refseq:XP_006712156.1|refseq:NP_001123952.1|refseq:NP_001123953.1|refseq:NP_001123954.1|refseq:NP_001123955.1|refseq:NP_006287.2|refseq:NP_001275765.1|refseq:NP_001275766.1|refseq:NP_001275767.1|refseq:NP_001275768.1|ensembl:ENSG00000028116.18(gene)|ensembl:ENST00000340157.9(transcript)|ensembl:ENST00000435505.6(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000659""(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR050235|mint:Q86Y07|rcsb pdb:2V62|rcsb pdb:5UU1|rcsb pdb:6NCG|rcsb pdb:8Q1Z|rcsb pdb:9FET|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:XP_005264597.1|panther:PTHR11909(orthology-group)|refseq:XP_016860347.1|refseq:XP_016860348.1|refseq:XP_016860349.1|refseq:XP_016860350.1|refseq:XP_016860351.1|refseq:XP_016860352.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:sDftNP5rKcTUJgpJAcbJsNzag0I9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96A33	intact:EBI-10726196	intact:EBI-720151|uniprotkb:Q96D00|uniprotkb:Q96JZ7|uniprotkb:Q9H3E4|uniprotkb:Q9NRG3|uniprotkb:B2RAS8|uniprotkb:D3DU20|ensembl:ENSP00000225726.5|ensembl:ENSP00000384888.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ccd47_human(display_long)|uniprotkb:CCDC47(gene name)|psi-mi:CCDC47(display_short)|uniprotkb:Calumin(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 47(gene name synonym)|uniprotkb:GK001(orf name)|uniprotkb:MSTP041(orf name)|uniprotkb:PSEC0077(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_064583.2|refseq:XP_005257584.1|ensembl:ENSG00000108588.15(gene)|ensembl:ENST00000225726.10(transcript)|ensembl:ENST00000403162.7(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006983""(ER overload response)|go:""GO:0009791""(post-embryonic development)|go:""GO:0016020""(membrane)|go:""GO:0030867""(rough endoplasmic reticulum membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0036503""(ERAD pathway)|go:""GO:0043022""(ribosome binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045048""(protein insertion into ER membrane)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0160063""(multi-pass transmembrane protein insertion into ER membrane)|go:""GO:0160064""(multi-pass translocon complex)|interpro:IPR012879(Protein of unknown function DUF1682)|mint:Q96A33|rcsb pdb:6W6L|panther:PTHR12883(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:DdZFzZrrc4culfYoex0Czf/X6SQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P08195	intact:EBI-10726196	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P51648	intact:EBI-10726196	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643.6|ensembl:ENSP00000461916.2|ensembl:ENSP00000463637.1|ensembl:ENSP00000500092.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR43570(orthology-group)|efo:""Orphanet:816""|ensembl:ENSG00000072210.19(gene)|ensembl:ENST00000176643.11(transcript)|ensembl:ENST00000579855.5(transcript)|ensembl:ENST00000581518.6(transcript)|ensembl:ENST00000672357.1(transcript)|go:""GO:0004028""(3-chloroallyl aldehyde dehydrogenase activity)|go:""GO:0004029""(""aldehyde dehydrogenase (NAD+) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006081""(aldehyde metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006714""(sesquiterpenoid metabolic process)|go:""GO:0007417""(central nervous system development)|go:""GO:0007422""(peripheral nervous system development)|go:""GO:0008544""(epidermis development)|go:""GO:0033306""(phytol metabolic process)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046458""(hexadecanal metabolic process)|go:""GO:0046577""(long-chain-alcohol oxidase activity)|go:""GO:0050061""(""long-chain fatty aldehyde dehydrogenase (NAD+) activity"")|go:""GO:0052814""(""medium-chain fatty aldehyde dehydrogenase (NAD+) activity"")|interpro:IPR012394(""Aldehyde dehydrogenase NAD(P)-dependent"")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9845614|refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9Y394	intact:EBI-10726196	intact:EBI-1387800|uniprotkb:Q9UKU2|uniprotkb:B2R896|ensembl:ENSP00000216500.5|ensembl:ENSP00000451882.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:dhrs7_human(display_long)|uniprotkb:DHRS7(gene name)|psi-mi:DHRS7(display_short)|uniprotkb:RETSDR4(gene name synonym)|uniprotkb:SDR34C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 34C member 1(gene name synonym)|uniprotkb:CGI-86(orf name)|uniprotkb:UNQ285/PRO3448(orf name)|uniprotkb:DHRS7A(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase 4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_057113.1|refseq:NP_001309209.1|panther:PTHR44269(orthology-group)|ensembl:ENSG00000100612.14(gene)|ensembl:ENST00000216500.9(transcript)|ensembl:ENST00000557185.6(transcript)|go:""GO:0004090""(""carbonyl reductase (NADPH) activity"")|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0052650""(""all-trans-retinol dehydrogenase (NADP+) activity"")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|interpro:IPR053011|mint:Q9Y394"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:OcTvozRJMb/lmA0bzcIcNpWIbYE9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P08240	intact:EBI-10726196	intact:EBI-726981|uniprotkb:Q9BVJ4|uniprotkb:A6NIB3|uniprotkb:B2R5Z8|uniprotkb:B4E0H3|uniprotkb:E9PJS4|ensembl:ENSP00000328023.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:srpra_human(display_long)|uniprotkb:SRPRA(gene name)|psi-mi:SRPRA(display_short)|uniprotkb:Docking protein alpha(gene name synonym)|uniprotkb:SRPR(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001171313.1|refseq:NP_003130.2|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000182934.12(gene)|ensembl:ENST00000332118.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005047""(signal recognition particle binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005785""(signal recognition particle receptor complex)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006613""(cotranslational protein targeting to membrane)|go:""GO:0006617""(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045047""(protein targeting to ER)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR007222(Signal recognition particle receptor, alpha subunit, N-terminal)|interpro:IPR011012(Longin-like)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101|mint:P08240|rcsb pdb:2FH5|rcsb pdb:2GO5|rcsb pdb:5L3Q|rcsb pdb:6Y32|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|panther:PTHR43134(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:4ag/lxPfDGSDWhpnuwQynTvCpuU9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9BZF1	intact:EBI-10726196	intact:EBI-2684038|uniprotkb:Q52LQ3|uniprotkb:Q9P277|uniprotkb:Q8WXP8|uniprotkb:A8K1T2|uniprotkb:E9PE66|uniprotkb:E9PE68|uniprotkb:Q68D75|ensembl:ENSP00000261183.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:osbl8_human(display_long)|uniprotkb:OSBP10(gene name synonym)|uniprotkb:KIAA1451(gene name synonym)|uniprotkb:ORP8(gene name synonym)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001003712.1|refseq:NP_065892.1|refseq:XP_005268678.1|refseq:XP_006719287.1|refseq:NP_001306581.1|refseq:NP_001306584.1|dip:DIP-56130N|ensembl:ENSG00000091039.17(gene)|ensembl:ENST00000261183.8(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005548""(phospholipid transporter activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0010891""(negative regulation of triglyceride storage)|go:""GO:0015485""(cholesterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0016020""(membrane)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032541""(cortical endoplasmic reticulum)|go:""GO:0036150""(phosphatidylserine acyl-chain remodeling)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0090204""(protein localization to nuclear pore)|go:""GO:0140343""(phosphatidylserine transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q9BZF1|rcsb pdb:1V88|rcsb pdb:5U77|rcsb pdb:5U78|rcsb pdb:8P7A|reactome:R-HSA-1482801|panther:PTHR10972(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:KwZ5DFeGTIM3p/yP3XBNgr/v3O09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9HBM0	intact:EBI-10726196	intact:EBI-11337963|uniprotkb:Q9NVW0|uniprotkb:Q9UF91|uniprotkb:Q9H2F4|uniprotkb:Q9NT70|uniprotkb:Q9H2U5|uniprotkb:Q6P1Q3|ensembl:ENSP00000410083.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:veza_human(display_long)|uniprotkb:VEZT(gene name)|psi-mi:VEZT(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_060069.3|refseq:XP_006719553.1|refseq:XP_016875091.1|ensembl:ENSG00000028203.19(gene)|ensembl:ENST00000436874.6(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0002142""(stereocilia ankle link complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0017022""(myosin binding)|go:""GO:0060171""(stereocilium membrane)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR026858|interpro:IPR026859|mint:Q9HBM0|panther:PTHR15989(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:RYaab97a5nn3YOaR7O7/rb9AjXk9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q14677	intact:EBI-10726196	intact:EBI-1171113|uniprotkb:Q8NAF1|uniprotkb:Q96E05|uniprotkb:D3DQJ6|uniprotkb:B7Z6F8|intact:EBI-28971708|ensembl:ENSP00000388340.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:epn4_human(display_long)|uniprotkb:CLINT1(gene name)|psi-mi:CLINT1(display_short)|uniprotkb:ENTH(gene name synonym)|uniprotkb:EPN4(gene name synonym)|uniprotkb:EPNR(gene name synonym)|uniprotkb:KIAA0171(gene name synonym)|uniprotkb:Epsin-4(gene name synonym)|uniprotkb:Epsin-related protein(gene name synonym)|uniprotkb:Enthoprotin(gene name synonym)|uniprotkb:Clathrin-interacting protein localized in the trans-Golgi region(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001182484.1|refseq:NP_001182485.1|refseq:NP_055481.1|panther:PTHR12276(orthology-group)|dip:DIP-45604N|ensembl:ENSG00000113282.14(gene)|ensembl:ENST00000411809.7(transcript)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0016020""(membrane)|go:""GO:0030125""(clathrin vesicle coat)|go:""GO:0030276""(clathrin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q14677|rcsb pdb:1XGW|rcsb pdb:2QY7|rcsb pdb:2V8S|reactome:R-HSA-432722"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:cflzNAWnEQR6zTr4d+hwfy1doC49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8N511	intact:EBI-10726196	intact:EBI-10265825|ensembl:ENSP00000292114.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tm199_human(display_long)|uniprotkb:TMEM199(gene name)|psi-mi:TMEM199(display_short)|uniprotkb:C17orf32(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000244045.13(gene)|ensembl:ENST00000292114.8(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0008142""(oxysterol binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0030663""(COPI-coated vesicle membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0070072""(vacuolar proton-transporting V-type ATPase complex assembly)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR021013|mint:Q8N511|refseq:NP_689677.1|efo:""Orphanet:466703""|panther:PTHR31394(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:rk4iRiCiPucGTNfFJWXGKL01xh09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P50851	intact:EBI-10726196	intact:EBI-1052167|uniprotkb:Q9H2U3|uniprotkb:Q9H2U4|uniprotkb:Q8NFQ0|uniprotkb:Q4W5J4|uniprotkb:Q4W5L6|ensembl:ENSP00000349629.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:lrba_human(display_long)|uniprotkb:CDC4-like protein(gene name synonym)|uniprotkb:Beige-like protein(gene name synonym)|uniprotkb:LRBA(gene name)|psi-mi:LRBA(display_short)|uniprotkb:BGL(gene name synonym)|uniprotkb:CDC4L(gene name synonym)|uniprotkb:LBA(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"dip:DIP-50531N|ensembl:ENSG00000198589.15(gene)|ensembl:ENST00000357115.9(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0034497""(protein localization to phagophore assembly site)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR010508(Protein of unknown function DUF1088)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|interpro:IPR046851|interpro:IPR046852|interpro:IPR050865|mint:P50851|rcsb pdb:1T77|refseq:NP_001186211.2|refseq:NP_006717.2|refseq:XP_011530736.1|efo:""Orphanet:445018""|panther:PTHR13743(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:FSUTaFKy63UUratp7X29LN/f1F49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9P035	intact:EBI-10726196	intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|ensembl:ENSP00000261875.5|uniprotkb:B4DRF4|intact:EBI-28973764	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_057479.2|ensembl:ENSG00000074696.13(gene)|ensembl:ENST00000261875.10(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0018812""(3-hydroxyacyl-CoA dehydratase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030148""(sphingolipid biosynthetic process)|go:""GO:0030497""(fatty acid elongation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042761""(very long-chain fatty acid biosynthetic process)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0046726""(positive regulation by virus of viral protein levels in host cell)|go:""GO:0102158""(""very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"")|go:""GO:1902532""(negative regulation of intracellular signal transduction)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876|panther:PTHR11035(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O75976	intact:EBI-10726196	intact:EBI-3916308|uniprotkb:B7Z7T9|uniprotkb:B7ZAU4|uniprotkb:F5GZH6|uniprotkb:Q86SH9|uniprotkb:O15377|uniprotkb:Q86XE6|ensembl:ENSP00000225719.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:cbpd_human(display_long)|uniprotkb:CPD(gene name)|psi-mi:CPD(display_short)|uniprotkb:Metallocarboxypeptidase D(gene name synonym)|uniprotkb:gp180(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001295.2|refseq:NP_001186704.1|ensembl:ENSG00000108582.12(gene)|ensembl:ENST00000225719.9(transcript)|go:""GO:0004181""(metallocarboxypeptidase activity)|go:""GO:0004185""(serine-type carboxypeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006518""(peptide metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0016485""(protein processing)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR033848|interpro:IPR034224|interpro:IPR050753|mint:O75976|rcsb pdb:5AQ0|reactome:R-HSA-432722|reactome:R-HSA-9696264|reactome:R-HSA-9696273|panther:PTHR11532(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:PC6PFm4D7KoT4utNwyIe57VUwbY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O75396	intact:EBI-10726196	intact:EBI-1058865|uniprotkb:A8K1G0|ensembl:ENSP00000463393.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_004883.3|ensembl:ENSG00000265808.4(gene)|ensembl:ENST00000578049.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0015031""(protein transport)|go:""GO:0030133""(transport vesicle)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042470""(melanosome)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048280""(vesicle fusion with Golgi apparatus)|go:""GO:1902902""(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:8HR0|reactome:R-HSA-1236974|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|dip:DIP-50458N|panther:PTHR45837(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:DRKtD169T9eYZ2kFufLapidvcKs9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P02786	intact:EBI-10726196	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224.4|ensembl:ENSP00000376197.3|ensembl:ENSP00000513646.1|ensembl:ENSP00000513654.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:476113""|ensembl:ENSG00000072274.14(gene)|ensembl:ENST00000360110.9(transcript)|ensembl:ENST00000392396.7(transcript)|ensembl:ENST00000698280.1(transcript)|ensembl:ENST00000698291.1(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004998""(transferrin receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010039""(response to iron ion)|go:""GO:0010042""(response to manganese ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010637""(negative regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033572""(transferrin transport)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0046688""(response to copper ion)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0072562""(blood microparticle)|go:""GO:0098944""(postsynaptic recycling endosome membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|interpro:IPR046450|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|rcsb pdb:7ZQS|rcsb pdb:8P0Z|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9725554|refseq:NP_001121620.1|refseq:NP_001300894.1|refseq:NP_001300895.1|refseq:NP_003225.2|dip:DIP-2736N|panther:PTHR10404(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q86UE4	intact:EBI-10726196	intact:EBI-1046588|uniprotkb:Q8TCX3|uniprotkb:Q6PK07|ensembl:ENSP00000338235.3|uniprotkb:Q05DH2|uniprotkb:Q52QU9	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:lyric_human(display_long)|uniprotkb:Lysine-rich CEACAM1 co-isolated protein(gene name synonym)|uniprotkb:3D3/LYRIC(gene name synonym)|uniprotkb:Metastasis adhesion protein(gene name synonym)|uniprotkb:Astrocyte elevated gene-1 protein(gene name synonym)|uniprotkb:MTDH(gene name)|psi-mi:MTDH(display_short)|uniprotkb:AEG1(gene name synonym)|uniprotkb:LYRIC(gene name synonym)|uniprotkb:Metadherin(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000147649.10(gene)|ensembl:ENST00000336273.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046581""(intercellular canaliculus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR031402|interpro:IPR052305|mint:Q86UE4|rcsb pdb:4QMG|refseq:NP_848927.2|panther:PTHR23251(orthology-group)|ensembl:ENSP00000338235.3"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:daZhKhAOeoKGjfl0IXt1fZXn/I09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9H8Y8	intact:EBI-10726196	intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|uniprotkb:B4DKT0|intact:EBI-28970723|ensembl:ENSP00000234160.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806.13(gene)|ensembl:ENST00000234160.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0006996""(organelle organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016020""(membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0061951""(establishment of protein localization to plasma membrane)|go:""GO:0070925""(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658|panther:PTHR12893(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:xSy3HsObmteg/doer5eLoZiz+fU9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96S66	intact:EBI-10726196	intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|intact:EBI-40264131|ensembl:ENSP00000349456.2|ensembl:ENSP00000358986.3|ensembl:ENSP00000502251.1|ensembl:ENSP00000502457.1|ensembl:ENSP00000502648.1|ensembl:ENSP00000502836.1|ensembl:ENSP00000508473.1|ensembl:ENSP00000508563.1|ensembl:ENSP00000508607.1|ensembl:ENSP00000508816.1|ensembl:ENSP00000508884.1|ensembl:ENSP00000508952.1|ensembl:ENSP00000508982.1|ensembl:ENSP00000509013.1|ensembl:ENSP00000509036.1|ensembl:ENSP00000509218.1|ensembl:ENSP00000509330.1|ensembl:ENSP00000509420.1|ensembl:ENSP00000509451.1|ensembl:ENSP00000509533.1|ensembl:ENSP00000509544.1|ensembl:ENSP00000509584.1|ensembl:ENSP00000509782.1|ensembl:ENSP00000509936.1|ensembl:ENSP00000509960.1|ensembl:ENSP00000509990.1|ensembl:ENSP00000510067.1|ensembl:ENSP00000510137.1|ensembl:ENSP00000510142.1|ensembl:ENSP00000510291.1|ensembl:ENSP00000510352.1|ensembl:ENSP00000510582.1|ensembl:ENSP00000510602.1|ensembl:ENSP00000510666.1|ensembl:ENSP00000510675.1|ensembl:ENSP00000510715.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:clcc1_human(display_long)|uniprotkb:ER anion channel 1(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein(gene name synonym)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940.17(gene)|ensembl:ENST00000356970.6(transcript)|ensembl:ENST00000369969.7(transcript)|ensembl:ENST00000674849.1(transcript)|ensembl:ENST00000675508.1(transcript)|ensembl:ENST00000675654.1(transcript)|ensembl:ENST00000675956.1(transcript)|ensembl:ENST00000685014.1(transcript)|ensembl:ENST00000685104.1(transcript)|ensembl:ENST00000685497.1(transcript)|ensembl:ENST00000685540.1(transcript)|ensembl:ENST00000686078.1(transcript)|ensembl:ENST00000686776.1(transcript)|ensembl:ENST00000686821.1(transcript)|ensembl:ENST00000687328.1(transcript)|ensembl:ENST00000687449.1(transcript)|ensembl:ENST00000687591.1(transcript)|ensembl:ENST00000687865.1(transcript)|ensembl:ENST00000688285.1(transcript)|ensembl:ENST00000688778.1(transcript)|ensembl:ENST00000689189.1(transcript)|ensembl:ENST00000689351.1(transcript)|ensembl:ENST00000689359.1(transcript)|ensembl:ENST00000689991.1(transcript)|ensembl:ENST00000690509.1(transcript)|ensembl:ENST00000690756.1(transcript)|ensembl:ENST00000690781.1(transcript)|ensembl:ENST00000690874.1(transcript)|ensembl:ENST00000691513.1(transcript)|ensembl:ENST00000691556.1(transcript)|ensembl:ENST00000691731.1(transcript)|ensembl:ENST00000692404.1(transcript)|ensembl:ENST00000692511.1(transcript)|ensembl:ENST00000692795.1(transcript)|ensembl:ENST00000693089.1(transcript)|ensembl:ENST00000693336.1(transcript)|ensembl:ENST00000693673.1(transcript)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0034707""(chloride channel complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|interpro:IPR009231(Mid-1-related chloride channel)|mint:Q96S66|panther:PTHR34093(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q13586	intact:EBI-10726196	intact:EBI-448878|uniprotkb:Q8N382|uniprotkb:E9PQJ4|ensembl:ENSP00000300737.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR15136(orthology-group)|efo:""Orphanet:2593""|efo:""Orphanet:317430""|efo:""Orphanet:3204""|dip:DIP-31121N|ensembl:ENSG00000167323.13(gene)|ensembl:ENST00000300737.8(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0002115""(store-operated calcium entry)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005513""(detection of calcium ion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0032237""(activation of store-operated calcium channel activity)|go:""GO:0032541""(cortical endoplasmic reticulum)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045762""(positive regulation of adenylate cyclase activity)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0070166""(enamel mineralization)|go:""GO:2001256""(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|mint:Q13586|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|refseq:NP_003147.2"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O75787	intact:EBI-10726196	intact:EBI-2512037|uniprotkb:Q8NG15|uniprotkb:Q8NBP3|uniprotkb:Q5QTQ7|uniprotkb:Q9UG89|uniprotkb:Q96FV6|uniprotkb:Q9H2P8|uniprotkb:Q96LB5|uniprotkb:Q6T7F5|uniprotkb:B7Z9I3|ensembl:ENSP00000490083.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	"psi-mi:renr_human(display_long)|uniprotkb:ATP6AP2(gene name)|psi-mi:ATP6AP2(display_short)|uniprotkb:ATP6IP2(gene name synonym)|uniprotkb:CAPER(gene name synonym)|uniprotkb:ELDF10(gene name synonym)|uniprotkb:Renin/prorenin receptor(gene name synonym)|uniprotkb:""ATPase H(+)-transporting lysosomal accessory protein 2""(gene name synonym)|uniprotkb:""ATPase H(+)-transporting lysosomal-interacting protein 2""(gene name synonym)|uniprotkb:Vacuolar ATP synthase membrane sector-associated protein M8-9(gene name synonym)|uniprotkb:N14F(gene name synonym)|uniprotkb:Embryonic liver differentiation factor 10(gene name synonym)|uniprotkb:HT028(orf name)|uniprotkb:MSTP009(orf name)|uniprotkb:PSEC0072(orf name)|uniprotkb:ER-localized type I transmembrane adapter(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:363654""|efo:""Orphanet:93952""|ensembl:ENSG00000182220.15(gene)|ensembl:ENST00000636580.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0002003""(angiotensin maturation)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0021626""(central nervous system maturation)|go:""GO:0021903""(rostrocaudal neural tube patterning)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030424""(axon)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0032591""(dendritic spine membrane)|go:""GO:0032914""(positive regulation of transforming growth factor beta1 production)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0048069""(eye pigmentation)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0051452""(intracellular pH reduction)|go:""GO:0060323""(head morphogenesis)|go:""GO:0061795""(Golgi lumen acidification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR012493(Renin receptor-like)|mint:O75787|rcsb pdb:3LBS|rcsb pdb:3LC8|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:NP_005756.2|panther:PTHR13351(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:v4lEPX23LdYqPi8dQX4MZG+tQZg9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q92575	intact:EBI-10726196	intact:EBI-723441|uniprotkb:Q4ZG56|uniprotkb:Q8IYM5|intact:EBI-28978946|uniprotkb:A8K9W4|ensembl:ENSP00000272638.9	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ubxn4_human(display_long)|uniprotkb:Erasin(gene name synonym)|uniprotkb:UBXN4(gene name)|psi-mi:UBXN4(display_short)|uniprotkb:KIAA0242(gene name synonym)|uniprotkb:UBXDC1(gene name synonym)|uniprotkb:UBXD2(gene name synonym)|uniprotkb:UBX domain-containing protein 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_055422.1|ensembl:ENSG00000144224.17(gene)|ensembl:ENST00000272638.14(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0036503""(ERAD pathway)|interpro:IPR001012(UBX)|interpro:IPR029071|interpro:IPR036249|mint:Q92575|rcsb pdb:2KXJ|panther:PTHR46424(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:rWCmtHlje9EFw7YVQQNJBBH4bLE9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P04844	intact:EBI-10726196	intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530.6|ensembl:ENSP00000517679.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001129243.1|refseq:NP_002942.2|refseq:NP_001311235.1|refseq:NP_001311234.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1|ensembl:ENSG00000118705.18(gene)|ensembl:ENSG00000291973.1(gene)|ensembl:ENST00000237530.11(transcript)|ensembl:ENST00000709412.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0036211""(protein modification process)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|panther:PTHR12640(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P05556	intact:EBI-10726196	intact:EBI-703066|intact:EBI-4289597|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5|ensembl:ENSP00000303351.3|ensembl:ENSP00000379350.2|ensembl:ENSP00000398029.2|ensembl:ENSP00000404546.3|ensembl:ENSP00000502882.1|ensembl:ENSP00000503546.1|ensembl:ENSP00000503916.1|ensembl:ENSP00000504205.1|ensembl:ENSP00000504444.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|ensembl:ENSG00000150093.20(gene)|ensembl:ENST00000302278.8(transcript)|ensembl:ENST00000396033.6(transcript)|ensembl:ENST00000417122.7(transcript)|ensembl:ENST00000437302.6(transcript)|ensembl:ENST00000677999.1(transcript)|ensembl:ENST00000678701.1(transcript)|ensembl:ENST00000678943.1(transcript)|ensembl:ENST00000678952.1(transcript)|dip:DIP-312N|ensembl:ENST00000678989.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001726""(ruffle)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002020""(protease binding)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006968""(cellular defense response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007517""(muscle organ development)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008305""(integrin complex)|go:""GO:0008354""(germ cell migration)|go:""GO:0008542""(visual learning)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010710""(regulation of collagen catabolic process)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0014704""(intercalated disc)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030175""(filopodium)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031623""(receptor internalization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0033631""(cell-cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034665""(integrin alpha1-beta1 complex)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0034667""(integrin alpha3-beta1 complex)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0034674""(integrin alpha5-beta1 complex)|go:""GO:0034675""(integrin alpha6-beta1 complex)|go:""GO:0034677""(integrin alpha7-beta1 complex)|go:""GO:0034678""(integrin alpha8-beta1 complex)|go:""GO:0034679""(integrin alpha9-beta1 complex)|go:""GO:0034680""(integrin alpha10-beta1 complex)|go:""GO:0034681""(integrin alpha11-beta1 complex)|go:""GO:0034682""(integrin alphav-beta1 complex)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043197""(dendritic spine)|go:""GO:0043235""(receptor complex)|go:""GO:0043236""(laminin binding)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045743""(positive regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048626""(myoblast fate specification)|go:""GO:0048675""(axon extension)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051951""(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0055037""(recycling endosome)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060912""(cardiac cell fate specification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097386""(glial cell projection)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150053""(cerebellar climbing fiber to Purkinje cell synapse)|go:""GO:0150103""(reactive gliosis)|go:""GO:1900748""(positive regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901979""(regulation of inward rectifier potassium channel activity)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905806""(regulation of synapse pruning)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|rcsb pdb:7CEB|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEC|rcsb pdb:7NWL|rcsb pdb:7NXD|rcsb pdb:8RPQ|rcsb pdb:9CKV|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9634597|reactome:R-HSA-9679191|reactome:R-HSA-9725554|reactome:R-HSA-9830674|reactome:R-HSA-9860927|panther:PTHR10082(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8TCJ2	intact:EBI-10726196	intact:EBI-2256290|ensembl:ENSP00000295770.2|uniprotkb:Q96JZ4|uniprotkb:Q96KY7	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:stt3b_human(display_long)|uniprotkb:STT3B(gene name)|psi-mi:STT3B(display_short)|uniprotkb:SIMP(gene name synonym)|uniprotkb:Source of immunodominant MHC-associated peptides homolog(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000163527.11(gene)|ensembl:ENST00000295770.4(transcript)|go:""GO:0004579""(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0006516""(glycoprotein catabolic process)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036503""(ERAD pathway)|go:""GO:0043686""(co-translational protein modification)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0046872""(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|interpro:IPR048307|interpro:IPR048999|mint:Q8TCJ2|rcsb pdb:6S7T|refseq:NP_849193.1|efo:""Orphanet:370924""|panther:PTHR13872(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:4F+9LbIZTFRoczuphd1jzuhnFDo9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P27824	intact:EBI-10726196	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000247461.4|ensembl:ENSP00000391646.2|ensembl:ENSP00000421434.2|ensembl:ENSP00000421813.2|ensembl:ENSP00000424063.1|ensembl:ENSP00000424745.2|ensembl:ENSP00000491760.1|ensembl:ENSP00000492372.1|ensembl:ENSP00000492868.1|ensembl:ENSP00000505013.1|ensembl:ENSP00000505202.1|ensembl:ENSP00000505526.1|ensembl:ENSP00000505960.1|ensembl:ENSP00000506003.1|ensembl:ENSP00000506021.1|ensembl:ENSP00000506061.1|ensembl:ENSP00000506078.1|ensembl:ENSP00000506509.1|ensembl:ENSP00000506568.1|ensembl:ENSP00000506583.1|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|ensembl:ENSG00000127022.16(gene)|ensembl:ENSG00000283777.2(gene)|ensembl:ENST00000247461.9(transcript)|ensembl:ENST00000452673.6(transcript)|ensembl:ENST00000502296.6(transcript)|ensembl:ENST00000504734.5(transcript)|ensembl:ENST00000509563.2(transcript)|ensembl:ENST00000513246.6(transcript)|ensembl:ENST00000638425.1(transcript)|ensembl:ENST00000638706.2(transcript)|ensembl:ENST00000639938.1(transcript)|ensembl:ENST00000680013.1(transcript)|ensembl:ENST00000680042.1(transcript)|ensembl:ENST00000680092.1(transcript)|ensembl:ENST00000680618.1(transcript)|ensembl:ENST00000681072.1(transcript)|ensembl:ENST00000681168.1(transcript)|ensembl:ENST00000681476.1(transcript)|ensembl:ENST00000681674.1(transcript)|ensembl:ENST00000681712.1(transcript)|ensembl:ENST00000681733.1(transcript)|ensembl:ENST00000681903.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006457""(protein folding)|go:""GO:0009306""(protein secretion)|go:""GO:0016020""(membrane)|go:""GO:0019082""(viral protein processing)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0036503""(ERAD pathway)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0044322""(endoplasmic reticulum quality control compartment)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098793""(presynapse)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|dip:DIP-457N|panther:PTHR11073(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P54886	intact:EBI-10726196	intact:EBI-1210304|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44|ensembl:ENSP00000360268.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000059573.9(gene)|ensembl:ENST00000371224.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004349""(glutamate 5-kinase activity)|go:""GO:0004350""(glutamate-5-semialdehyde dehydrogenase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006536""(glutamate metabolic process)|go:""GO:0006561""(proline biosynthetic process)|go:""GO:0006592""(ornithine biosynthetic process)|go:""GO:0009266""(response to temperature stimulus)|go:""GO:0019240""(citrulline biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539|reactome:R-HSA-9837999|refseq:NP_001017423.1|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|refseq:NP_002851.2|efo:""Orphanet:35664""|efo:""Orphanet:447753""|efo:""Orphanet:447757""|efo:""Orphanet:447760""|efo:""Orphanet:90348""|panther:PTHR11063(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P14625	intact:EBI-10726196	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)|uniprotkb:HSPC4(gene name synonym)|uniprotkb:Heat shock protein family C member 4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR11528(orthology-group)|refseq:NP_003290.1|ensembl:ENSG00000166598.16(gene)|ensembl:ENST00000299767.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030496""(midbody)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|reactome:R-HSA-8957275|go:""GO:0031247""(actin rod assembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033018""(sarcoplasmic reticulum lumen)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042470""(melanosome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051208""(sequestering of calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071287""(cellular response to manganese ion)|go:""GO:0071318""(cellular response to ATP)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|rcsb pdb:7ULL|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|dip:DIP-36060N"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P68371	intact:EBI-10726196	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:65""|ensembl:ENSG00000188229.6(gene)|ensembl:ENST00000340384.5(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0005879""(axonemal microtubule)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0036126""(sperm flagellum)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0045171""(intercellular bridge)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072686""(mitotic spindle)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|rcsb pdb:7UN1|rcsb pdb:7UNG|rcsb pdb:8J07|rcsb pdb:8SH7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9833482|refseq:NP_006079.1|panther:PTHR11588(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q15836	intact:EBI-10726196	intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666.6	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_004772.1|ensembl:ENSG00000049245.13(gene)|ensembl:ENST00000054666.11(transcript)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0030133""(transport vesicle)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061025""(membrane fusion)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:1903531""(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-56422N|panther:PTHR45701(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q15006	intact:EBI-10726196	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_055488.1|ensembl:ENSG00000104412.8(gene)|ensembl:ENST00000220853.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0042406""(extrinsic component of endoplasmic reticulum membrane)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072546""(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|interpro:IPR055217|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|rcsb pdb:8EOI|rcsb pdb:8J0N|rcsb pdb:8J0O|rcsb pdb:8S9S|rcsb pdb:9C7V|panther:PTHR12760(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q15904	intact:EBI-10726196	intact:EBI-714667|uniprotkb:Q8NBT4|uniprotkb:Q9H0C7|uniprotkb:A6ZKI4|ensembl:ENSP00000358777.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:vas1_human(display_long)|uniprotkb:V-ATPase S1 accessory protein(gene name synonym)|uniprotkb:V-ATPase Ac45 subunit(gene name synonym)|uniprotkb:Protein XAP-3(gene name synonym)|uniprotkb:ATP6AP1(gene name)|psi-mi:ATP6AP1(display_short)|uniprotkb:ATP6IP1(gene name synonym)|uniprotkb:ATP6S1(gene name synonym)|uniprotkb:VATPS1(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:Vacuolar proton pump subunit S1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:XP_011529481.1|ensembl:ENSG00000071553.18(gene)|ensembl:ENST00000369762.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016469""(proton-transporting two-sector ATPase complex)|go:""GO:0030641""(regulation of cellular pH)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0036035""(osteoclast development)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0051452""(intracellular pH reduction)|go:""GO:0061795""(Golgi lumen acidification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:0141109""(transporter activator activity)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR008388(ATPase, V1 complex, subunit S1)|interpro:IPR046755|interpro:IPR046756|mint:Q15904|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|rcsb pdb:7UNF|reactome:R-HSA-77387|reactome:R-HSA-8980692|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:NP_001174.2|panther:PTHR12471(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:c5zqmRYvzBfRy1BdJteDGueEjY49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q7KZF4	intact:EBI-10726196	intact:EBI-1044112|uniprotkb:Q13122|uniprotkb:Q96AG0|ensembl:ENSP00000346762.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_055205.2|dip:DIP-29613N|rcsb pdb:3BDL|ensembl:ENSG00000197157.11(gene)|ensembl:ENST00000354725.8(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0010564""(regulation of cell cycle process)|go:""GO:0010587""(miRNA catabolic process)|go:""GO:0016020""(membrane)|rcsb pdb:3OMC|go:""GO:0016894""(endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031332""(RNAi effector complex)|go:""GO:0042470""(melanosome)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097433""(dense body)|go:""GO:1905172""(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071(""Staphylococcal nuclease (SNase-like), OB-fold"")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|interpro:IPR047386|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|rcsb pdb:7KNW|rcsb pdb:7KNX|reactome:R-HSA-6802952|panther:PTHR12302(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9Y385	intact:EBI-10726196	intact:EBI-988826|uniprotkb:Q5W0N4|uniprotkb:Q9BZ32|uniprotkb:Q9NQL3|uniprotkb:Q9NY66|uniprotkb:Q9P011|uniprotkb:Q9P0S0|uniprotkb:Q9UF10|uniprotkb:A8K3F9|uniprotkb:Q53F25|ensembl:ENSP00000451261.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ub2j1_human(display_long)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:Yeast ubiquitin-conjugating enzyme UBC6 homolog E(gene name synonym)|uniprotkb:UBE2J1(gene name)|psi-mi:UBE2J1(display_short)|uniprotkb:NCUBE1(gene name synonym)|uniprotkb:CGI-76(orf name)|uniprotkb:HSPC153(orf name)|uniprotkb:HSPC205(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme J1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_057105.2|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR050113|mint:Q9Y385|reactome:R-HSA-983168|ensembl:ENSG00000198833.7(gene)|ensembl:ENST00000435041.3(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007286""(spermatid development)|go:""GO:0010935""(regulation of macrophage cytokine production)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0036503""(ERAD pathway)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:1904153""(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|dip:DIP-45598N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:nc3+V3Qxy1ZDhTWgTPLakJukxPM9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O75915	intact:EBI-10726196	intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_006398.1|ensembl:ENSG00000144746.7(gene)|ensembl:ENST00000273258.4(transcript)|go:""GO:0002037""(negative regulation of L-glutamate import across plasma membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0007611""(learning or memory)|go:""GO:0008631""(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:""GO:0010917""(negative regulation of mitochondrial membrane potential)|go:""GO:0015031""(protein transport)|go:""GO:0015813""(L-glutamate transmembrane transport)|go:""GO:0016020""(membrane)|go:""GO:0032874""(positive regulation of stress-activated MAPK cascade)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0051051""(negative regulation of transport)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098712""(L-glutamate import across plasma membrane)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|panther:PTHR12859(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q00325	intact:EBI-10726196	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|uniprotkb:Q7Z7N7|uniprotkb:B3KS34|ensembl:ENSP00000228318.3|ensembl:ENSP00000447310.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:s25a3_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Phosphate carrier protein, mitochondrial(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR45671(orthology-group)|ensembl:ENSG00000075415.15(gene)|ensembl:ENST00000228318.8(transcript)|ensembl:ENST00000551917.5(transcript)|go:""GO:0005315""(phosphate transmembrane transporter activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0015317""(""phosphate:proton symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0035435""(phosphate ion transmembrane transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990547""(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|efo:""Orphanet:91130"""	-	-	crc64:78714C85931B22D5	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9Y5M8	intact:EBI-10726196	intact:EBI-355393|uniprotkb:Q8N2D8|uniprotkb:Q6P595|ensembl:ENSP00000418401.1|ensembl:ENSP00000503923.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:srprb_human(display_long)|uniprotkb:SRPRB(gene name)|psi-mi:SRPRB(display_short)|uniprotkb:PSEC0230(orf name)|uniprotkb:Protein APMCF1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_067026.3|ensembl:ENSG00000144867.13(gene)|ensembl:ENST00000466490.7(transcript)|ensembl:ENST00000678299.1(transcript)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005785""(signal recognition particle receptor complex)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0006617""(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:""GO:0016020""(membrane)|go:""GO:0045047""(protein targeting to ER)|interpro:IPR019009|interpro:IPR024156|interpro:IPR027417|mint:Q9Y5M8|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|dip:DIP-50218N|panther:PTHR11485(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:pHUdnCvOhMRYIJg//OJ+SlCard49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q71U36	intact:EBI-10726196	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|ensembl:ENSP00000301071.7|ensembl:ENSP00000439020.2|ensembl:ENSP00000520499.1|uniprotkb:G3V1U9|intact:EBI-10989786	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:171680""|efo:""Orphanet:45358""|efo:""Orphanet:467166""|efo:""Orphanet:994""|ensembl:ENSG00000167552.16(gene)|ensembl:ENST00000295766.9(transcript)|ensembl:ENST00000301071.12(transcript)|ensembl:ENST00000715688.1(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000793""(condensed chromosome)|go:""GO:0001764""(neuron migration)|go:""GO:0001964""(startle response)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005879""(axonemal microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007017""(microtubule-based process)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007613""(memory)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0008542""(visual learning)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0010001""(glial cell differentiation)|go:""GO:0010467""(gene expression)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016787""(hydrolase activity)|go:""GO:0021542""(dentate gyrus development)|go:""GO:0021696""(cerebellar cortex morphogenesis)|go:""GO:0021859""(pyramidal neuron differentiation)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0030705""(cytoskeleton-dependent intracellular transport)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035641""(locomotory exploration behavior)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048853""(forebrain morphogenesis)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050807""(regulation of synapse organization)|go:""GO:0050808""(synapse organization)|go:""GO:0051301""(cell division)|mint:Q71U36|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0055037""(recycling endosome)|rcsb pdb:5JCO|go:""GO:0061744""(motor behavior)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0140058""(neuron projection arborization)|go:""GO:1902065""(response to L-glutamate)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|rcsb pdb:7UN1|rcsb pdb:7UNG|rcsb pdb:8J07|rcsb pdb:8SH7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9833482|refseq:NP_001257328.1|refseq:NP_001257329.1|refseq:NP_006000.2|dip:DIP-32773N|panther:PTHR11588(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8WUY9	intact:EBI-10726196	intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|uniprotkb:B4DUT4|ensembl:ENSP00000265036.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499.13(gene)|ensembl:ENST00000265036.10(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0016477""(cell migration)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0035556""(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|mint:Q8WUY9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|panther:PTHR16206(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P23528	intact:EBI-10726196	intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629.5|ensembl:ENSP00000432660.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_005498.1|ensembl:ENSG00000172757.13(gene)|ensembl:ENST00000308162.10(transcript)|ensembl:ENST00000525451.6(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0009615""(response to virus)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030043""(actin filament fragmentation)|go:""GO:0030426""(growth cone)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032587""(ruffle membrane)|go:""GO:0040019""(positive regulation of embryonic development)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0051293""(establishment of spindle localization)|go:""GO:0061001""(regulation of dendritic spine morphogenesis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|dip:DIP-33000N|panther:PTHR11913(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P51572	intact:EBI-10726196	intact:EBI-77683|uniprotkb:Q13836|uniprotkb:Q96CF0|uniprotkb:D3DWV5|uniprotkb:B3KQ79|ensembl:ENSP00000343458.6|ensembl:ENSP00000494052.1|ensembl:ENSP00000499882.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:bap31_human(display_long)|uniprotkb:BCAP31(gene name)|psi-mi:BCAP31(display_short)|uniprotkb:BAP31(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:6C6-AG tumor-associated antigen(gene name synonym)|uniprotkb:DXS1357E(gene name synonym)|uniprotkb:Protein CDM(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR12701(orthology-group)|efo:""Orphanet:369939""|efo:""Orphanet:369942""|ensembl:ENSG00000185825.17(gene)|ensembl:ENST00000345046.12(transcript)|ensembl:ENST00000647529.1(transcript)|ensembl:ENST00000672675.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016020""(membrane)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070973""(protein localization to endoplasmic reticulum exit site)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1904154""(positive regulation of retrograde protein transport, ER to cytosol)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:P51572|rcsb pdb:4JZL|rcsb pdb:4JZP|rcsb pdb:8XWX|reactome:R-HSA-111465|reactome:R-HSA-75153|reactome:R-HSA-8980692|reactome:R-HSA-983170|reactome:R-HSA-9833110|refseq:NP_001132913.1|refseq:NP_001132929.1|refseq:NP_001243376.1|refseq:NP_005736.3"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:m0aN00PLZJDWA/K1vEbla1W9+S89606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O95721	intact:EBI-10726196	intact:EBI-490676|ensembl:ENSP00000215730.6	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:snp29_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-29(gene name synonym)|uniprotkb:Soluble 29 kDa NSF attachment protein(gene name synonym)|uniprotkb:SNAP29(gene name)|psi-mi:SNAP29(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000099940.12(gene)|ensembl:ENST00000215730.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005776""(autophagosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006903""(vesicle targeting)|go:""GO:0015031""(protein transport)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0016240""(autophagosome membrane docking)|go:""GO:0019905""(syntaxin binding)|go:""GO:0020018""(ciliary pocket membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0061025""(membrane fusion)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098793""(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|mint:O95721|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-6798695|reactome:R-HSA-6811438|refseq:NP_004773.1|efo:""Orphanet:66631""|dip:DIP-56475N|panther:PTHR19305(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:4HyjERPnEDdBgiGt70N9oyrMN1k9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8N5K1	intact:EBI-10726196	intact:EBI-1045797|uniprotkb:Q7Z3D5|ensembl:ENSP00000273986.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:cisd2_human(display_long)|uniprotkb:CDGSH2(gene name synonym)|uniprotkb:ERIS(gene name synonym)|uniprotkb:ZCD2(gene name synonym)|uniprotkb:Endoplasmic reticulum intermembrane small protein(gene name synonym)|uniprotkb:MitoNEET-related 1 protein(gene name synonym)|uniprotkb:CISD2(gene name)|psi-mi:CISD2(display_short)|uniprotkb:Nutrient-deprivation autophagy factor-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:3463""|ensembl:ENSG00000145354.12(gene)|ensembl:ENST00000273986.10(transcript)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0003723""(RNA binding)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|interpro:IPR018967|interpro:IPR019610|interpro:IPR042216|interpro:IPR045131|mint:Q8N5K1|rcsb pdb:3FNV|rcsb pdb:4OO7|rcsb pdb:4OOA|rcsb pdb:7P0P|refseq:NP_001008389.1|panther:PTHR13680(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:YxickLtFNLILnuUDAXl1QqFadD09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q5VV42	intact:EBI-10726196	intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695.4|ensembl:ENSP00000367873.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	"psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:""tRNA-t(6)A37 methylthiotransferase""(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_060244.2|ensembl:ENSG00000145996.11(gene)|ensembl:ENST00000274695.8(transcript)|ensembl:ENST00000378610.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0016020""(membrane)|go:""GO:0035598""(""tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase activity"")|go:""GO:0035600""(tRNA methylthiolation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0061712""(""obsolete tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase"")|go:""GO:1990145""(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315|panther:PTHR11918(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O15126	intact:EBI-10726196	intact:EBI-954338|uniprotkb:O43587|uniprotkb:Q96BX1|uniprotkb:Q96QK5|uniprotkb:Q6FG23|ensembl:ENSP00000481022.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:scam1_human(display_long)|uniprotkb:SCAMP1(gene name)|psi-mi:SCAMP1(display_short)|uniprotkb:SCAMP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_004857.4|refseq:NP_001277158.1|ensembl:ENSG00000085365.18(gene)|ensembl:ENST00000621999.5(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0055038""(recycling endosome membrane)|interpro:IPR007273(SCAMP)|mint:O15126|reactome:R-HSA-6798695|panther:PTHR10687(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:Utuf4fnpMHS2yG4zfccdB2enfxI9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q658Y4	intact:EBI-10726196	intact:EBI-3045545|uniprotkb:Q8TE89|uniprotkb:Q658T5|uniprotkb:B6YY23|ensembl:ENSP00000335082.7	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:f91a1_human(display_long)|uniprotkb:FAM91A1(gene name)|psi-mi:FAM91A1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_659400.2|refseq:NP_001304846.1|refseq:NP_001304847.1|ensembl:ENSG00000176853.16(gene)|ensembl:ENST00000334705.12(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0099041""(vesicle tethering to Golgi)|interpro:IPR028091|interpro:IPR028097|interpro:IPR039199|mint:Q658Y4|rcsb pdb:8JJ9|rcsb pdb:8XFB|rcsb pdb:8Z9M|reactome:R-HSA-9013407|panther:PTHR28441(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:0Fq4tmA02p3P6sxVWlt0RA24hrc9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96AG4	intact:EBI-10726196	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|uniprotkb:B2RE83|ensembl:ENSP00000225972.7	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_060979.2|ensembl:ENSG00000108829.10(gene)|ensembl:ENST00000225972.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045296""(cadherin binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050216|mint:Q96AG4|panther:PTHR45752(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9H3P7	intact:EBI-10726196	intact:EBI-1791792|ensembl:ENSP00000355777.5|uniprotkb:Q5VTJ0|uniprotkb:Q6P9F1|uniprotkb:Q8IZC5|uniprotkb:Q8N4D6|uniprotkb:Q9H6U3|uniprotkb:B2RB29	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:gcp60_human(display_long)|uniprotkb:GOCAP1(gene name synonym)|uniprotkb:GOLPH1(gene name synonym)|uniprotkb:ACBD3(gene name)|psi-mi:ACBD3(display_short)|uniprotkb:GCP60(gene name synonym)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000182827.9(gene)|ensembl:ENST00000366812.6(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006694""(steroid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR009038(GOLD)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|interpro:IPR036598|interpro:IPR052269|mint:Q9H3P7|rcsb pdb:2N72|rcsb pdb:2N73|rcsb pdb:5LZ1|rcsb pdb:5LZ3|rcsb pdb:5LZ6|rcsb pdb:5TDQ|rcsb pdb:6HLN|rcsb pdb:6HLT|rcsb pdb:6HLV|rcsb pdb:6HLW|rcsb pdb:6HM8|rcsb pdb:6HMV|reactome:R-HSA-432722|refseq:NP_073572.2|dip:DIP-40673N|panther:PTHR22973(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:jAaMXnoXG6RGj+lAgIYk1inXA6o9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O95210	intact:EBI-10726196	intact:EBI-2947137|intact:EBI-28977817|uniprotkb:B3KVZ9|ensembl:ENSP00000237642.6	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:stbd1_human(display_long)|uniprotkb:STBD1(gene name)|psi-mi:STBD1(display_short)|uniprotkb:Glycophagy cargo receptor STBD1(gene name synonym)|uniprotkb:GENX-3414(orf name)|uniprotkb:Genethonin-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_003934.1|ensembl:ENSG00000118804.9(gene)|ensembl:ENST00000237642.7(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030315""(T-tubule)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061723""(glycophagy)|go:""GO:0061753""(substrate localization to autophagosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:2001069""(glycogen binding)|go:""GO:2001070""(starch binding)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR034838|mint:O95210|rcsb pdb:8X8A|rcsb pdb:8X8K|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|panther:PTHR15048(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:nCP8UCnge2HywBnBiNfBW1GLJ0U9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q13190	intact:EBI-10726196	intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|uniprotkb:F8W8Q9|ensembl:ENSP00000294179.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_003155.2|refseq:NP_001231595.1|ensembl:ENSG00000162236.13(gene)|ensembl:ENST00000294179.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0006906""(vesicle fusion)|go:""GO:0012505""(endomembrane system)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031982""(vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045296""(cadherin binding)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048278""(vesicle docking)|go:""GO:0048280""(vesicle fusion with Golgi apparatus)|go:""GO:0090166""(Golgi disassembly)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|interpro:IPR045242|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001317223.1|dip:DIP-56987N|panther:PTHR19957(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P51149	intact:EBI-10726196	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062.3|ensembl:ENSP00000501618.1|ensembl:ENSP00000502000.1|ensembl:ENSP00000502088.1|ensembl:ENSP00000502486.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000075785.14(gene)|ensembl:ENST00000265062.8(transcript)|ensembl:ENST00000674589.1(transcript)|ensembl:ENST00000675342.1(transcript)|ensembl:ENST00000675497.1(transcript)|ensembl:ENST00000676214.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0019003""(GDP binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0036466""(synaptic vesicle recycling via endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045453""(bone resorption)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048524""(positive regulation of viral process)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090383""(phagosome acidification)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0097208""(alveolar lamellar body)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:1903542""(negative regulation of exosomal secretion)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1905366""(negative regulation of intralumenal vesicle formation)|go:""GO:1905394""(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:3LAW|rcsb pdb:6IYB|rcsb pdb:6WCW|rcsb pdb:7F6J|rcsb pdb:8KB8|rcsb pdb:8ZQ3|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|refseq:NP_004628.4|efo:""Orphanet:99936""|dip:DIP-39879N|panther:PTHR47981(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96NT0	intact:EBI-10726196	intact:EBI-2810325|uniprotkb:Q9BR88|ensembl:ENSP00000259229.2|uniprotkb:B4DJ47	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:cc115_human(display_long)|uniprotkb:CCDC115(gene name)|psi-mi:CCDC115(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000136710.10(gene)|ensembl:ENST00000259229.7(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0016020""(membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070072""(vacuolar proton-transporting V-type ATPase complex assembly)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR040357|mint:Q96NT0|reactome:R-HSA-8980692|refseq:NP_001308047.1|refseq:NP_001308048.1|refseq:NP_115733.2|efo:""Orphanet:468684""|panther:PTHR31996(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:cUCb36pVMieoV7ZwXQPtD/kIAXY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9NRW7	intact:EBI-10726196	intact:EBI-1782543|ensembl:ENSP00000495563.1|uniprotkb:Q15715|uniprotkb:Q9Y4Z6|uniprotkb:Q5T4P6|uniprotkb:D3DUZ9|uniprotkb:F5H8K1|uniprotkb:Q53FR8	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:vps45_human(display_long)|uniprotkb:VPS45(gene name)|psi-mi:VPS45(display_short)|uniprotkb:VPS45A(gene name synonym)|uniprotkb:VPS45B(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000136631.16(gene)|ensembl:ENST00000644510.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:Q9NRW7|reactome:R-HSA-6811438|reactome:R-HSA-9754560|reactome:R-HSA-983231|refseq:NP_001266282.1|refseq:NP_001266283.1|refseq:NP_009190.2|dip:DIP-46823N|efo:""Orphanet:369852""|panther:PTHR11679(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:EO8eXkh8EW/0AN2p5OqHL4yvXV09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q86VP6	intact:EBI-10726196	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_060918.2|ensembl:ENSG00000111530.13(gene)|ensembl:ENST00000545606.6(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0010265""(SCF complex assembly)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017025""(TBP-class protein binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031461""(cullin-RING ubiquitin ligase complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0045899""(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013932(""TATA-binding protein interacting (TIP20)"")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|rcsb pdb:7Z8R|rcsb pdb:7Z8T|rcsb pdb:7Z8V|rcsb pdb:7ZBW|rcsb pdb:7ZBZ|rcsb pdb:8CDJ|rcsb pdb:8CDK|rcsb pdb:8H3Q|rcsb pdb:8OR0|rcsb pdb:8OR2|rcsb pdb:8OR3|rcsb pdb:8OR4|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|dip:DIP-31608N|panther:PTHR12696(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P16615	intact:EBI-10726196	intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	"psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:""Endoplasmic reticulum class 1/2 Ca(2+) ATPase""(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR42861(orthology-group)|efo:""Orphanet:218""|efo:""Orphanet:79151""|ensembl:ENSG00000174437.18(gene)|ensembl:ENST00000539276.7(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0005388""(P-type calcium transporter activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006984""(ER-nucleus signaling pathway)|go:""GO:0007155""(cell adhesion)|go:""GO:0008544""(epidermis development)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0010882""(regulation of cardiac muscle contraction by calcium ion signaling)|go:""GO:0014801""(longitudinal sarcoplasmic reticulum)|go:""GO:0014883""(transition between fast and slow fiber)|go:""GO:0014898""(cardiac muscle hypertrophy in response to stress)|go:""GO:0016020""(membrane)|go:""GO:0016240""(autophagosome membrane docking)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0032470""(positive regulation of endoplasmic reticulum calcium ion concentration)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0033292""(T-tubule organization)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0070296""(sarcoplasmic reticulum calcium ion transport)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0086036""(regulation of cardiac muscle cell membrane potential)|go:""GO:0086039""(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:""GO:0090534""(calcium ion-transporting ATPase complex)|go:""GO:0097470""(ribbon synapse)|go:""GO:0098909""(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:""GO:0106222""(lncRNA binding)|go:""GO:0140056""(organelle localization by membrane tethering)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1903233""(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:""GO:1903515""(calcium ion transport from cytosol to endoplasmic reticulum)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1990036""(calcium ion import into sarcoplasmic reticulum)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|rcsb pdb:7E7S|rcsb pdb:7W7T|rcsb pdb:7W7U|rcsb pdb:7W7V|rcsb pdb:7W7W|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_005253945.1|refseq:XP_011536704.1|dip:DIP-33868N"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q53EU6	intact:EBI-10726196	intact:EBI-11337979|uniprotkb:Q6GPI6|uniprotkb:Q68CJ4|uniprotkb:Q96NA3|ensembl:ENSP00000264409.4|ensembl:ENSP00000378651.2|ensembl:ENSP00000482571.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	"psi-mi:gpat3_human(display_long)|uniprotkb:GPAT3(gene name)|psi-mi:GPAT3(display_short)|uniprotkb:1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10(gene name synonym)|uniprotkb:1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9(gene name synonym)|uniprotkb:AGPAT9(gene name synonym)|uniprotkb:""Acyl-CoA:glycerol-3-phosphate acyltransferase 3""(gene name synonym)|uniprotkb:Lung cancer metastasis-associated protein 1(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase theta(gene name synonym)|uniprotkb:MAG-1(gene name synonym)|uniprotkb:MAG1(gene name synonym)|uniprotkb:HMFN0839(orf name)|uniprotkb:UNQ2753/PRO6492(orf name)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001243350.1|refseq:NP_001243351.1|refseq:NP_116106.2|refseq:XP_016864270.1|ensembl:ENSG00000138678.11(gene)|ensembl:ENST00000264409.5(transcript)|ensembl:ENST00000395226.6(transcript)|ensembl:ENST00000611707.4(transcript)|go:""GO:0003841""(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:""GO:0004366""(glycerol-3-phosphate O-acyltransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006072""(glycerol-3-phosphate metabolic process)|go:""GO:0006654""(phosphatidic acid biosynthetic process)|go:""GO:0016024""(CDP-diacylglycerol biosynthetic process)|go:""GO:0019432""(triglyceride biosynthetic process)|go:""GO:0032006""(regulation of TOR signaling)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR045252|mint:Q53EU6|reactome:R-HSA-1483166|panther:PTHR23063(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:LofyvxRlpiC9Y80bR/S4/i1Y7UQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9BZH6	intact:EBI-10726196	intact:EBI-2009923|uniprotkb:Q5VWA1|uniprotkb:Q9P2J6|ensembl:ENSP00000263461.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:wdr11_human(display_long)|uniprotkb:WDR11(gene name)|psi-mi:WDR11(display_short)|uniprotkb:KIAA1351(gene name synonym)|uniprotkb:BRWD2(gene name synonym)|uniprotkb:WDR15(gene name synonym)|uniprotkb:Bromodomain and WD repeat-containing protein 2(gene name synonym)|uniprotkb:WD repeat-containing protein 15(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR14593(orthology-group)|efo:""Orphanet:432""|efo:""Orphanet:478""|efo:""Orphanet:95496""|ensembl:ENSG00000120008.16(gene)|ensembl:ENST00000263461.11(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005930""(axoneme)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007507""(heart development)|go:""GO:0008589""(regulation of smoothened signaling pathway)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0036064""(ciliary basal body)|go:""GO:0060271""(cilium assembly)|go:""GO:0060322""(head development)|go:""GO:0099041""(vesicle tethering to Golgi)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR039694|mint:Q9BZH6|rcsb pdb:8XFB|rcsb pdb:8Z9M|reactome:R-HSA-9013407|refseq:NP_060587.8"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:Kl337t8mCHvvkb8oi0z8Ohl72a09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8NBN3	intact:EBI-10726196	intact:EBI-2687855|uniprotkb:Q9P103|uniprotkb:Q9Y3Y7|uniprotkb:Q9BS46|uniprotkb:Q6NT77|uniprotkb:Q8NCA4|ensembl:ENSP00000374484.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tm87a_human(display_long)|uniprotkb:Elkin1(gene name synonym)|uniprotkb:PSEC0094(orf name)|uniprotkb:TMEM87A(gene name)|psi-mi:TMEM87A(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001273416.1|refseq:NP_001103973.1|refseq:NP_056312.2|ensembl:ENSG00000103978.17(gene)|ensembl:ENST00000389834.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001726""(ruffle)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0050976""(detection of mechanical stimulus involved in sensory perception of touch)|go:""GO:0071260""(cellular response to mechanical stimulus)|interpro:IPR009637(Transmembrane receptor, eukaryota)|interpro:IPR053937|interpro:IPR054101|mint:Q8NBN3|rcsb pdb:8CTJ|rcsb pdb:8HSI|rcsb pdb:8HTT|rcsb pdb:8KB4|reactome:R-HSA-8980692|panther:PTHR21229(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:GdHPH2U8wRKfLAAUi0q2lw4ZtCA9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9Y6I9	intact:EBI-10726196	intact:EBI-10329860|uniprotkb:Q9UKD7|uniprotkb:B3KN87|ensembl:ENSP00000340969.5|ensembl:ENSP00000378497.1|ensembl:ENSP00000396628.1|ensembl:ENSP00000398802.1|ensembl:ENSP00000408186.1|ensembl:ENSP00000477946.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tx264_human(display_long)|uniprotkb:TEX264(gene name)|psi-mi:TEX264(display_short)|uniprotkb:Putative secreted protein Zsig11(gene name synonym)|uniprotkb:ZSIG11(gene name synonym)|uniprotkb:UNQ337/PRO536(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:XP_011532107.1|refseq:NP_001123356.1|refseq:NP_001230654.1|refseq:NP_001230655.1|refseq:NP_001230656.1|refseq:NP_001265124.1|refseq:NP_057010.1|refseq:XP_006713258.1|refseq:XP_006713260.1|ensembl:ENSG00000164081.13(gene)|ensembl:ENST00000341333.10(transcript)|ensembl:ENST00000395057.5(transcript)|ensembl:ENST00000415259.5(transcript)|ensembl:ENST00000416589.5(transcript)|ensembl:ENST00000457573.5(transcript)|ensembl:ENST00000611400.4(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005657""(replication fork)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0061709""(reticulophagy)|go:""GO:0106300""(protein-DNA covalent cross-linking repair)|interpro:IPR011256(Regulatory factor, effector, bacterial)|mint:Q9Y6I9|rcsb pdb:7VEC|rcsb pdb:7VED|reactome:R-HSA-114608|panther:PTHR15949(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:Agv5w3SF9VdUL0o2qXZ7erRtyJ09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O75410	intact:EBI-10726196	intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|uniprotkb:D3DSX6|ensembl:ENSP00000321703.4|uniprotkb:B4E302	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000147526.20(gene)|ensembl:ENST00000317827.9(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0016020""(membrane)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030496""(midbody)|go:""GO:0035259""(nuclear glucocorticoid receptor binding)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0042975""(peroxisome proliferator activated receptor binding)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0051301""(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542936.1|refseq:XP_011542938.1|refseq:XP_011542939.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|efo:""Orphanet:251576""|efo:""Orphanet:251579""|panther:PTHR13924(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9HD20	intact:EBI-10726196	intact:EBI-3940599|uniprotkb:B3KTA7|uniprotkb:B3KPJ2|uniprotkb:Q9H6C6|uniprotkb:Q6NT90|uniprotkb:Q6ZMG7|ensembl:ENSP00000349877.6	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:at131_human(display_long)|uniprotkb:ATP13A1(gene name)|psi-mi:ATP13A1(display_short)|uniprotkb:ATP13A(gene name synonym)|uniprotkb:KIAA1825(gene name synonym)|uniprotkb:CGI-152(orf name)|uniprotkb:Endoplasmic reticulum P5A-ATPase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_065143.2|ensembl:ENSG00000105726.17(gene)|ensembl:ENST00000357324.11(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0015031""(protein transport)|go:""GO:0015410""(ABC-type manganese transporter activity)|go:""GO:0015662""(P-type ion transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019829""(ATPase-coupled monoatomic cation transmembrane transporter activity)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0055085""(transmembrane transport)|go:""GO:0140567""(membrane protein dislocase activity)|go:""GO:0140569""(extraction of mislocalized protein from ER membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006544(""P-type ATPase of unknown pump specificity (type V)"")|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|interpro:IPR047820|mint:Q9HD20|reactome:R-HSA-936837|panther:PTHR45630(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:p4PEgZhH5QhoHI+InDMbLvdIBP09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8TBA6	intact:EBI-10726196	intact:EBI-11278147|uniprotkb:O95287|uniprotkb:Q03962|uniprotkb:Q2TS49|uniprotkb:Q9UQQ7|uniprotkb:C9JRU1|ensembl:ENSP00000163416.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:goga5_human(display_long)|uniprotkb:GOLGA5(gene name)|psi-mi:GOLGA5(display_short)|uniprotkb:Cell proliferation-inducing gene 31 protein(gene name synonym)|uniprotkb:Golgin-84(gene name synonym)|uniprotkb:Protein Ret-II(gene name synonym)|uniprotkb:RET-fused gene 5 protein(gene name synonym)|uniprotkb:RETII(gene name synonym)|uniprotkb:RFG5(gene name synonym)|uniprotkb:PIG31(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:146""|ensembl:ENSG00000066455.13(gene)|ensembl:ENST00000163416.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000301""(retrograde transport, vesicle recycling within Golgi)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0007030""(Golgi organization)|go:""GO:0016020""(membrane)|go:""GO:0030133""(transport vesicle)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031985""(Golgi cisterna)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048193""(Golgi vesicle transport)|interpro:IPR019177|mint:Q8TBA6|reactome:R-HSA-6811438|refseq:NP_005104.3|refseq:XP_011535722.1|panther:PTHR13815(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:PtiO2qhE4u4CFxYqL+bqph4lmT09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O75694	intact:EBI-10726196	intact:EBI-1050769|uniprotkb:Q9UBE9|uniprotkb:Q9UFL5|intact:EBI-28983292|ensembl:ENSP00000231498.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:nu155_human(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0791(gene name synonym)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000113569.17(gene)|ensembl:ENST00000231498.8(transcript)|go:""GO:0000972""(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0016020""(membrane)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035196""(miRNA processing)|go:""GO:0036228""(protein localization to nuclear inner membrane)|go:""GO:0044611""(nuclear pore inner ring)|go:""GO:0086014""(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|interpro:IPR042538|mint:O75694|rcsb pdb:5A9Q|rcsb pdb:5IJN|rcsb pdb:5IJO|rcsb pdb:7EYE|rcsb pdb:7EYF|rcsb pdb:7EYQ|rcsb pdb:7PER|rcsb pdb:7R1Y|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9705671|refseq:NP_004289.1|refseq:NP_705618.1|efo:""Orphanet:334""|panther:PTHR10350(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:k6LjWvJdqtT78G4Wu12rJX/2WHo9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9Y679	intact:EBI-10726196	intact:EBI-1058701|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8|ensembl:ENSP00000366748.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_853553.1|ensembl:ENSG00000115307.17(gene)|ensembl:ENST00000377526.4(transcript)|go:""GO:0005776""(autophagosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034389""(lipid droplet organization)|go:""GO:0036503""(ERAD pathway)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140042""(lipid droplet formation)|go:""GO:1990044""(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR048056|mint:Q9Y679|rcsb pdb:2EKF|rcsb pdb:7LEW|panther:PTHR15486(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q15005	intact:EBI-10726196	intact:EBI-1043352|uniprotkb:Q15507|uniprotkb:Q3KQT0|uniprotkb:Q641R4|uniprotkb:Q6FG65|uniprotkb:Q6IRX0|uniprotkb:Q6P1P4|uniprotkb:Q96HU9|ensembl:ENSP00000263672.6	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:spcs2_human(display_long)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym)|uniprotkb:SPCS2(gene name)|psi-mi:SPCS2(display_short)|uniprotkb:KIAA0102(gene name synonym)|uniprotkb:SPC25(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_055567.2|dip:DIP-47276N|ensembl:ENSG00000118363.13(gene)|ensembl:ENST00000263672.11(transcript)|go:""GO:0005787""(signal peptidase complex)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006465""(signal peptide processing)|go:""GO:0045047""(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|mint:Q15005|rcsb pdb:7P2P|rcsb pdb:7P2Q|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|reactome:R-HSA-9828806|panther:PTHR13085(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:3POhDKvg+aoZiz2XRTC+m77XTAw9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8NEN9	intact:EBI-10726196	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_776152.1|mint:Q8NEN9|rcsb pdb:7F6J|ensembl:ENSG00000165650.12(gene)|ensembl:ENST00000334464.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0046872""(metal ion binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|interpro:IPR046349|panther:PTHR21519(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96A49	intact:EBI-10726196	intact:EBI-10770179|uniprotkb:Q68CP1|uniprotkb:Q96C60|uniprotkb:Q96JQ6|uniprotkb:Q96T20|ensembl:ENSP00000369500.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:syap1_human(display_long)|uniprotkb:SYAP1(gene name)|psi-mi:SYAP1(display_short)|uniprotkb:BSD domain-containing signal transducer and Akt interactor protein(gene name synonym)|uniprotkb:PRO3113(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_116185.2|ensembl:ENSG00000169895.6(gene)|ensembl:ENST00000380155.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0038203""(TORC2 signaling)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043204""(perikaryon)|go:""GO:0045202""(synapse)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0048172""(regulation of short-term neuronal synaptic plasticity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:1990314""(cellular response to insulin-like growth factor stimulus)|interpro:IPR005607(BSD)|interpro:IPR035925|interpro:IPR051494|mint:Q96A49|rcsb pdb:1X3A|panther:PTHR16019(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:+gHfLl7YaR8geuci2/cAYP8CiKA9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P35610	intact:EBI-10726196	intact:EBI-6621955|uniprotkb:A6NC40|uniprotkb:A8K3P4|uniprotkb:A9Z1V7|uniprotkb:B4DU95|uniprotkb:Q5T0X4|uniprotkb:Q8N1E4|ensembl:ENSP00000356591.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	"psi-mi:soat1_human(display_long)|uniprotkb:SOAT1(gene name)|psi-mi:SOAT1(display_short)|uniprotkb:ACACT(gene name synonym)|uniprotkb:ACACT1(gene name synonym)|uniprotkb:ACAT(gene name synonym)|uniprotkb:ACAT1(gene name synonym)|uniprotkb:SOAT(gene name synonym)|uniprotkb:STAT(gene name synonym)|uniprotkb:""Acyl-coenzyme A:cholesterol acyltransferase 1""(gene name synonym)|uniprotkb:Cholesterol acyltransferase 1(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:XP_011508213.1|refseq:NP_001239440.1|refseq:NP_001239441.1|refseq:NP_003092.4|ensembl:ENSG00000057252.13(gene)|ensembl:ENST00000367619.8(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0004772""(sterol O-acyltransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0010742""(macrophage derived foam cell differentiation)|go:""GO:0010878""(cholesterol storage)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0034379""(very-low-density lipoprotein particle assembly)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0034736""(cholesterol O-acyltransferase activity)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042986""(positive regulation of amyloid precursor protein biosynthetic process)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|interpro:IPR030687|mint:P35610|rcsb pdb:6L47|rcsb pdb:6L48|rcsb pdb:6P2J|rcsb pdb:6P2P|rcsb pdb:6VUM|reactome:R-HSA-8964038|panther:PTHR10408(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:jX8d8x9ZYOdpE2Vg+C5ECuX9zQQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P39656	intact:EBI-10726196	intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457.3|uniprotkb:B4DJE3|uniprotkb:B4DLI2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000244038.11(gene)|ensembl:ENST00000415136.6(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0034097""(response to cytokine)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042110""(T cell activation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548|refseq:NP_005207.2|efo:""Orphanet:300536""|panther:PTHR10830(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P00387	intact:EBI-10726196	intact:EBI-1046040|uniprotkb:O75675|uniprotkb:Q8TDL8|uniprotkb:Q8WTS8|uniprotkb:Q9UEN4|uniprotkb:Q9UEN5|uniprotkb:Q9UL55|uniprotkb:Q9UL56|uniprotkb:B1AHF2|uniprotkb:B7Z7L3|ensembl:ENSP00000338461.6	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:nb5r3_human(display_long)|uniprotkb:Diaphorase-1(gene name synonym)|uniprotkb:CYB5R3(gene name)|psi-mi:CYB5R3(display_short)|uniprotkb:DIA1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000100243.22(gene)|ensembl:ENST00000352397.10(transcript)|go:""GO:0004128""(""cytochrome-b5 reductase activity, acting on NAD(P)H"")|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005833""(hemoglobin complex)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0008015""(blood circulation)|go:""GO:0016020""(membrane)|go:""GO:0016208""(AMP binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043531""(ADP binding)|go:""GO:0051287""(NAD binding)|go:""GO:0071949""(FAD binding)|go:""GO:1903958""(nitric-oxide synthase complex)|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834(""NADH:cytochrome b5 reductase (CBR)"")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|mint:P00387|rcsb pdb:1UMK|rcsb pdb:7THG|rcsb pdb:7TNV|rcsb pdb:7TSW|rcsb pdb:7W3O|reactome:R-HSA-196836|reactome:R-HSA-211945|reactome:R-HSA-6798695|refseq:NP_000389.1|refseq:NP_001123291.1|refseq:NP_001165131.1|refseq:NP_001165132.1|refseq:NP_015565.1|dip:DIP-50463N|efo:""Orphanet:621""|panther:PTHR19370(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:Q8JTO6AXZ8LE4FXZAzOw2p4b6HY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q86UL3	intact:EBI-10726196	intact:EBI-3925330|uniprotkb:Q86V89|ensembl:ENSP00000380184.3|uniprotkb:Q2TU73	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	"psi-mi:gpat4_human(display_long)|uniprotkb:GPAT4(gene name)|psi-mi:GPAT4(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 6(gene name synonym)|uniprotkb:AGPAT6(gene name synonym)|uniprotkb:""Acyl-CoA:glycerol-3-phosphate acyltransferase 4""(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase zeta(gene name synonym)|uniprotkb:TSARG7(gene name synonym)|uniprotkb:Testis spermatogenesis apoptosis-related protein 7(gene name synonym)|uniprotkb:UNQ551/PRO1108(orf name)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:XP_011542694.1|refseq:XP_011542695.1|refseq:XP_011542696.1|refseq:NP_848934.1|ensembl:ENSG00000158669.11(gene)|ensembl:ENST00000396987.7(transcript)|go:""GO:0002071""(glandular epithelial cell maturation)|go:""GO:0003841""(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:""GO:0004366""(glycerol-3-phosphate O-acyltransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006637""(acyl-CoA metabolic process)|go:""GO:0006654""(phosphatidic acid biosynthetic process)|go:""GO:0006656""(phosphatidylcholine biosynthetic process)|go:""GO:0007595""(lactation)|go:""GO:0008610""(lipid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016024""(CDP-diacylglycerol biosynthetic process)|go:""GO:0019432""(triglyceride biosynthetic process)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0046339""(diacylglycerol metabolic process)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR045252|mint:Q86UL3|reactome:R-HSA-1483166|refseq:XP_016868531.1|panther:PTHR23063(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:0j/B1lxhVshCx6yA7HNCsemsuD49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q15084	intact:EBI-10726196	intact:EBI-1043087|uniprotkb:Q6ZSH5|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7|ensembl:ENSP00000272227.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|refseq:NP_005733.1|ensembl:ENSG00000143870.13(gene)|ensembl:ENST00000272227.8(transcript)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006457""(protein folding)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0070062""(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|rcsb pdb:8CPQ|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|panther:PTHR45815(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P67812	intact:EBI-10726196	intact:EBI-1042500|uniprotkb:O75957|uniprotkb:P21378|uniprotkb:B4DUL4|uniprotkb:H0YK72|uniprotkb:H0YK83|uniprotkb:Q53FQ8|uniprotkb:B2RAD7|ensembl:ENSP00000268220.7	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:sc11a_human(display_long)|uniprotkb:SEC11A(gene name)|psi-mi:SEC11A(display_short)|uniprotkb:SPC18(gene name synonym)|uniprotkb:SPCS4A(gene name synonym)|uniprotkb:SEC11 homolog A(gene name synonym)|uniprotkb:SEC11-like protein 1(gene name synonym)|uniprotkb:Microsomal signal peptidase 18 kDa subunit(gene name synonym)|uniprotkb:Endopeptidase SP18(gene name synonym)|uniprotkb:SEC11L1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_055115.1|refseq:NP_001258847.1|refseq:NP_001258848.1|refseq:NP_001258849.1|refseq:NP_001258850.1|refseq:NP_001258851.1|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019533|interpro:IPR019756|interpro:IPR019758|ensembl:ENSG00000140612.14(gene)|ensembl:ENST00000268220.12(transcript)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005787""(signal peptidase complex)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006465""(signal peptide processing)|go:""GO:0008233""(peptidase activity)|go:""GO:0009615""(response to virus)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR036286|mint:P67812|rcsb pdb:7P2P|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|reactome:R-HSA-9828806|dip:DIP-50359N|panther:PTHR10806(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:zaXzKdryO7BUa6mNJF2DsvIxIJU9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9P0I2	intact:EBI-10726196	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046.2|ensembl:ENSP00000474771.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_060917.1|ensembl:ENSG00000125037.13(gene)|ensembl:ENST00000245046.7(transcript)|ensembl:ENST00000470827.3(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072546""(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|mint:Q9P0I2|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|rcsb pdb:8EOI|rcsb pdb:8J0N|rcsb pdb:8J0O|rcsb pdb:8S9S|rcsb pdb:9C7V|reactome:R-HSA-8980692|panther:PTHR13116(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9BTX1	intact:EBI-10726196	intact:EBI-2552800|uniprotkb:Q9NVZ7|uniprotkb:Q9H9T6|uniprotkb:Q9NSG3|uniprotkb:Q9NSG4|uniprotkb:Q8NB76|uniprotkb:B4DHA3|uniprotkb:B4DQQ5|uniprotkb:G3XA81|ensembl:ENSP00000360483.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ndc1_human(display_long)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:TMEM48(gene name synonym)|uniprotkb:Transmembrane protein 48(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001162023.1|refseq:NP_060557.3|ensembl:ENSG00000058804.12(gene)|ensembl:ENST00000371429.4(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006999""(nuclear pore organization)|go:""GO:0007129""(homologous chromosome pairing at meiosis)|go:""GO:0007283""(spermatogenesis)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031965""(nuclear membrane)|go:""GO:0051028""(mRNA transport)|go:""GO:0051292""(nuclear pore complex assembly)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0070762""(nuclear pore transmembrane ring)|interpro:IPR019049|mint:Q9BTX1|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9705671|panther:PTHR13269(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:0HbFqC4o16ELLTSUfqACs1BD05I9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9UIQ6	intact:EBI-10726196	intact:EBI-2805360|uniprotkb:O00769|uniprotkb:Q9TNQ2|uniprotkb:Q9TNQ3|uniprotkb:Q9UIQ7|uniprotkb:Q59H76|uniprotkb:Q15145|ensembl:ENSP00000231368.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:lcap_human(display_long)|uniprotkb:OTASE(gene name synonym)|uniprotkb:Oxytocinase(gene name synonym)|uniprotkb:Insulin-regulated membrane aminopeptidase(gene name synonym)|uniprotkb:Insulin-responsive aminopeptidase(gene name synonym)|uniprotkb:Placental leucine aminopeptidase(gene name synonym)|uniprotkb:LNPEP(gene name)|psi-mi:LNPEP(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_005566.2|refseq:NP_787116.2|ensembl:ENSG00000113441.16(gene)|ensembl:ENST00000231368.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0002480""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007565""(female pregnancy)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0042277""(peptide binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|interpro:IPR045357|interpro:IPR050344|mint:Q9UIQ6|rcsb pdb:4P8Q|rcsb pdb:4PJ6|rcsb pdb:4Z7I|rcsb pdb:5C97|rcsb pdb:5JHQ|rcsb pdb:5MJ6|rcsb pdb:7ZYF|rcsb pdb:8CGP|rcsb pdb:8CGW|rcsb pdb:8P0I|reactome:R-HSA-1236977|reactome:R-HSA-1445148|reactome:R-HSA-983168|panther:PTHR11533(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:IOU7GW8f6aBYAjIUQXFKbU5Hqkw9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8WVM8	intact:EBI-10726196	intact:EBI-722569|uniprotkb:O60754|uniprotkb:O94990|uniprotkb:Q7Z529|uniprotkb:Q9BZI3|uniprotkb:Q9UNL3|uniprotkb:Q9Y6A8|uniprotkb:A8K2Z5|uniprotkb:B7Z4U7|uniprotkb:B7Z594|ensembl:ENSP00000390783.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:scfd1_human(display_long)|uniprotkb:Syntaxin-binding protein 1-like 2(gene name synonym)|uniprotkb:SLY1 homolog(gene name synonym)|uniprotkb:FKSG23(orf name)|uniprotkb:SCFD1(gene name)|psi-mi:SCFD1(display_short)|uniprotkb:KIAA0917(gene name synonym)|uniprotkb:STXBP1L2(gene name synonym)|uniprotkb:C14orf163(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001269961.1|refseq:NP_057190.2|refseq:NP_001244305.1|refseq:NP_878255.1|ensembl:ENSG00000092108.22(gene)|ensembl:ENST00000458591.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0009636""(response to toxic substance)|go:""GO:0019905""(syntaxin binding)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0051223""(regulation of protein transport)|go:""GO:0060628""(regulation of ER to Golgi vesicle-mediated transport)|go:""GO:1902902""(negative regulation of autophagosome assembly)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:Q8WVM8|reactome:R-HSA-204005|reactome:R-HSA-8980692|panther:PTHR11679(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:7cD2Z6zhuKLCd3ERB+pVNRdVexY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9H3N1	intact:EBI-10726196	intact:EBI-1051115|uniprotkb:Q8N487|uniprotkb:Q8NBN5|uniprotkb:Q9Y4T6|uniprotkb:B2R7A4|ensembl:ENSP00000393316.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tmx1_human(display_long)|uniprotkb:Transmembrane Trx-related protein(gene name synonym)|uniprotkb:TMX1(gene name)|psi-mi:TMX1(display_short)|uniprotkb:TXNDC1(gene name synonym)|uniprotkb:TMX(gene name synonym)|uniprotkb:TXNDC(gene name synonym)|uniprotkb:PSEC0085(orf name)|uniprotkb:UNQ235/PRO268(orf name)|uniprotkb:Thioredoxin domain-containing protein 1(gene name synonym)|uniprotkb:Protein disulfide-isomerase TMX1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_110382.3|ensembl:ENSG00000139921.13(gene)|ensembl:ENST00000457354.7(transcript)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0010868""(negative regulation of triglyceride biosynthetic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:1904294""(positive regulation of ERAD pathway)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR052454|mint:Q9H3N1|rcsb pdb:1X5E|panther:PTHR46107(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:ZJH5N22Dnrk+SXa3Ysqqfu1md/I9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q53GQ0	intact:EBI-10726196	intact:EBI-2963255|uniprotkb:A8K9B0|uniprotkb:Q9Y6G8|uniprotkb:Q96JU2|uniprotkb:D3DR23|uniprotkb:Q96EA9|ensembl:ENSP00000278353.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:dhb12_human(display_long)|uniprotkb:HSD17B12(gene name)|psi-mi:HSD17B12(display_short)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 12(gene name synonym)|uniprotkb:3-ketoacyl-CoA reductase(gene name synonym)|uniprotkb:SDR12C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 1(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 12(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_057226.1|ensembl:ENSG00000149084.13(gene)|ensembl:ENST00000278353.10(transcript)|go:""GO:0001968""(fibronectin binding)|go:""GO:0004303""(""estradiol 17-beta-dehydrogenase [NAD(P)+] activity"")|go:""GO:0005518""(collagen binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006703""(estrogen biosynthetic process)|go:""GO:0008201""(heparin binding)|go:""GO:0009923""(fatty acid elongase complex)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0019367""(fatty acid elongation, saturated fatty acid)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035338""(long-chain fatty-acyl-CoA biosynthetic process)|go:""GO:0141040""(very-long-chain 3-oxoacyl-CoA reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|interpro:IPR051019|mint:Q53GQ0|reactome:R-HSA-193048|reactome:R-HSA-75876|panther:PTHR43899(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:2R2pFY0c9yRuCvLU2J8n2urR+0o9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q14318	intact:EBI-10726196	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|uniprotkb:C8C9T5|ensembl:ENSP00000222308.4|ensembl:ENSP00000472302.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_036313.3|refseq:XP_011526165.1|refseq:NP_001295302.1|ensembl:ENSG00000105701.16(gene)|ensembl:ENST00000222308.8(transcript)|ensembl:ENST00000596558.6(transcript)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005740""(mitochondrial envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006915""(apoptotic process)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0021904""(dorsal/ventral neural tube patterning)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0043010""(camera-type eye development)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0048665""(neuron fate specification)|go:""GO:0070585""(protein localization to mitochondrion)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|go:""GO:1901524""(regulation of mitophagy)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR046357|interpro:IPR050754|mint:Q14318|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|dip:DIP-42200N|panther:PTHR46512(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O43402	intact:EBI-10726196	intact:EBI-741841|uniprotkb:C9JB21|ensembl:ENSP00000253457.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_006058.1|refseq:NP_001135760.1|ensembl:ENSG00000131148.9(gene)|ensembl:ENST00000253457.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0016020""(membrane)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072546""(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|mint:O43402|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|rcsb pdb:8EOI|rcsb pdb:8J0N|rcsb pdb:8J0O|rcsb pdb:8S9S|rcsb pdb:9C7V|panther:PTHR12941(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q15738	intact:EBI-10726196	intact:EBI-4280135|uniprotkb:D3DWT6|uniprotkb:O00344|ensembl:ENSP00000359297.3|ensembl:ENSP00000391854.1|ensembl:ENSP00000517980.1|ensembl:ENSP00000517982.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:nsdhl_human(display_long)|uniprotkb:NSDHL(gene name)|psi-mi:NSDHL(display_short)|uniprotkb:H105E3(gene name synonym)|uniprotkb:Protein H105e3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000147383.11(gene)|ensembl:ENSG00000292192.1(gene)|ensembl:ENST00000370274.8(transcript)|ensembl:ENST00000440023.5(transcript)|ensembl:ENST00000709998.1(transcript)|ensembl:ENST00000710000.1(transcript)|go:""GO:0000252""(""3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity"")|go:""GO:0001942""(hair follicle development)|go:""GO:0003854""(""3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity"")|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0102175""(""3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity"")|interpro:IPR002225(3-beta hydroxysteroid dehydrogenase/isomerase)|interpro:IPR036291|interpro:IPR050177|mint:Q15738|rcsb pdb:6JKG|rcsb pdb:6JKH|reactome:R-HSA-191273|refseq:NP_001123237.1|refseq:NP_057006.1|refseq:XP_011529480.1|efo:""Orphanet:139""|efo:""Orphanet:251383""|panther:PTHR10366(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:Hfd2Gvro+f9sk/Wn2Dxsgh1nbfo9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9Y6M7	intact:EBI-10726196	intact:EBI-1044546|uniprotkb:O60350|uniprotkb:Q6AHZ9|uniprotkb:Q9HC88|uniprotkb:Q9UIB9|uniprotkb:A6NIA8|uniprotkb:B2CI53|uniprotkb:B5M451|uniprotkb:B5M452|uniprotkb:B5M453|uniprotkb:B6DY52|uniprotkb:B6DY53|uniprotkb:C9JST9|uniprotkb:B5M449|uniprotkb:D3K174|uniprotkb:D3K175|intact:EBI-10982200|intact:EBI-11577841|ensembl:ENSP00000295736.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	"psi-mi:s4a7_human(display_long)|uniprotkb:Sodium bicarbonate cotransporter 2(gene name synonym)|uniprotkb:Sodium bicarbonate cotransporter 2b(gene name synonym)|uniprotkb:Solute carrier family 4 member 7(gene name synonym)|uniprotkb:SLC4A7(gene name)|psi-mi:SLC4A7(display_short)|uniprotkb:BT(gene name synonym)|uniprotkb:NBC2(gene name synonym)|uniprotkb:NBC2B(gene name synonym)|uniprotkb:NBC3(gene name synonym)|uniprotkb:SBC2(gene name synonym)|uniprotkb:SLC4A6(gene name synonym)|uniprotkb:NBCn1(gene name synonym)|uniprotkb:""Electroneutral Na/HCO(3) cotransporter""(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_003606.3|refseq:NP_001245308.1|refseq:NP_001245309.1|refseq:NP_001308032.1|refseq:NP_001308033.1|refseq:NP_001308034.1|refseq:NP_001308035.1|refseq:NP_001308036.1|refseq:NP_001308037.1|refseq:XP_016863017.1|refseq:XP_016863018.1|ensembl:ENSG00000033867.18(gene)|ensembl:ENST00000295736.9(transcript)|go:""GO:0005452""(""solute:inorganic anion antiporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006221""(pyrimidine nucleotide biosynthetic process)|go:""GO:0008509""(monoatomic anion transmembrane transporter activity)|go:""GO:0008510""(""sodium:bicarbonate symporter activity"")|go:""GO:0015701""(bicarbonate transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0032420""(stereocilium)|go:""GO:0051453""(regulation of intracellular pH)|go:""GO:0055085""(transmembrane transport)|go:""GO:0060117""(auditory receptor cell development)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0090383""(phagosome acidification)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|mint:Q9Y6M7|reactome:R-HSA-425381|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9035034|panther:PTHR11453(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:vsq90qG3qxPyZgkoyvS0MPamvOg9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P31689	intact:EBI-10726196	intact:EBI-347834|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9|ensembl:ENSP00000369127.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000086061.16(gene)|ensembl:ENST00000330899.5(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007283""(spermatogenesis)|go:""GO:0009408""(response to heat)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042026""(protein refolding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043508""(negative regulation of JUN kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051223""(regulation of protein transport)|go:""GO:0055131""(C3HC4-type RING finger domain binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070585""(protein localization to mitochondrion)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:1903748""(negative regulation of establishment of protein localization to mitochondrion)|go:""GO:1905259""(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|rcsb pdb:6E8M|rcsb pdb:8E2O|reactome:R-HSA-3371497|reactome:R-HSA-9841251|refseq:NP_001530.1|panther:PTHR43888(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9UHN6	intact:EBI-10726196	intact:EBI-2876905|uniprotkb:B2RTQ6|uniprotkb:Q8NBP6|uniprotkb:Q5T841|uniprotkb:Q5T840|uniprotkb:Q9P2D5|uniprotkb:Q5T839|uniprotkb:Q5T838|uniprotkb:A6H8W9|ensembl:ENSP00000366243.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ceip2_human(display_long)|uniprotkb:CEMIP2(gene name)|psi-mi:CEMIP2(display_short)|uniprotkb:KIAA1412(gene name synonym)|uniprotkb:TMEM2(gene name synonym)|uniprotkb:Transmembrane protein 2(gene name synonym)|uniprotkb:Cell migration-inducing hyaluronidase 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001129292.1|refseq:NP_037522.1|ensembl:ENSG00000135048.14(gene)|ensembl:ENST00000377044.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903670""(regulation of sprouting angiogenesis)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR019316|interpro:IPR039473|interpro:IPR039477|interpro:IPR052252|mint:Q9UHN6|rcsb pdb:8C6I|refseq:XP_005251926.1|panther:PTHR15535(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:LVdpEH7Df1biSXHseli56Y9l9XQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P63010	intact:EBI-10726196	intact:EBI-432924|ensembl:ENSP00000482315.1|uniprotkb:A6NJP3|uniprotkb:P21851|uniprotkb:Q96J19|intact:EBI-8011909|intact:MINT-8395045|uniprotkb:Q7Z451|intact:EBI-28970775	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ap2b1_human(display_long)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000006125.18(gene)|ensembl:ENST00000621914.4(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0005048""(signal sequence binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030131""(clathrin adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0035904""(aorta development)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0060976""(coronary vasculature development)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|rcsb pdb:2IV8|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:P63010|rcsb pdb:1E42|rcsb pdb:2G30|rcsb pdb:2IV9|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:4UQI|rcsb pdb:5M5R|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6QH7|rcsb pdb:6URI|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|rcsb pdb:6YAI|rcsb pdb:7OG1|rcsb pdb:7OHO|rcsb pdb:7OM8|rcsb pdb:7Z5C|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|refseq:NP_001025177.1|refseq:NP_001273.1|refseq:XP_005257994.1|refseq:XP_005257995.1|refseq:XP_011522757.1|refseq:XP_016879773.1|refseq:XP_016879775.1|dip:DIP-33098N|panther:PTHR11134(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:Q5oFhdE1hcmqu7xLG3MteCu0Zcg9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96HY6	intact:EBI-10726196	intact:EBI-1054024|uniprotkb:A6NIU5|uniprotkb:Q9BW47|uniprotkb:C9JSZ5|ensembl:ENSP00000346483.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ddrgk_human(display_long)|uniprotkb:DDRGK1(gene name)|psi-mi:DDRGK1(display_short)|uniprotkb:C20orf116(gene name synonym)|uniprotkb:UFBP1(gene name synonym)|uniprotkb:UFM1-binding and PCI domain-containing protein 1(gene name synonym)|uniprotkb:Dashurin(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:93352""|ensembl:ENSG00000198171.13(gene)|ensembl:ENST00000354488.8(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0033146""(regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051216""(cartilage development)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061709""(reticulophagy)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0071569""(protein ufmylation)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0140501""(positive regulation of reticulophagy)|go:""GO:0141185""(UFM1-modified protein reader activity)|go:""GO:1900100""(positive regulation of plasma cell differentiation)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|go:""GO:1902808""(positive regulation of cell cycle G1/S phase transition)|go:""GO:1903052""(positive regulation of proteolysis involved in protein catabolic process)|go:""GO:1903721""(positive regulation of I-kappaB phosphorylation)|go:""GO:1903895""(negative regulation of IRE1-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1905050""(positive regulation of metallopeptidase activity)|go:""GO:1905552""(positive regulation of protein localization to endoplasmic reticulum)|go:""GO:1905636""(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:""GO:1990592""(protein K69-linked ufmylation)|interpro:IPR019153|interpro:IPR036388|interpro:IPR036390|interpro:IPR050899|mint:Q96HY6|rcsb pdb:7W3N|rcsb pdb:8B9X|rcsb pdb:8C0D|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|reactome:R-HSA-8980692|refseq:NP_076424.1|panther:PTHR48176(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:a34FmuGjW3zh9eliKvmntHGU6qw9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9H2J7	intact:EBI-10726196	intact:EBI-11343466|uniprotkb:E7ESJ5|uniprotkb:B7Z2P7|uniprotkb:A8K592|uniprotkb:Q9H9F5|ensembl:ENSP00000266682.5|ensembl:ENSP00000505286.1|ensembl:ENSP00000505485.1|ensembl:ENSP00000505789.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:s6a15_human(display_long)|uniprotkb:SLC6A15(gene name)|psi-mi:SLC6A15(display_short)|uniprotkb:B0AT2(gene name synonym)|uniprotkb:NTT73(gene name synonym)|uniprotkb:SBAT1(gene name synonym)|uniprotkb:Sodium- and chloride-dependent neurotransmitter transporter NTT73(gene name synonym)|uniprotkb:Sodium-coupled branched-chain amino-acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 6 member 15(gene name synonym)|uniprotkb:Transporter v7-3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001139807.1|refseq:NP_060527.2|refseq:NP_877499.1|panther:PTHR11616(orthology-group)|ensembl:ENSG00000072041.18(gene)|ensembl:ENST00000266682.10(transcript)|ensembl:ENST00000680963.1(transcript)|ensembl:ENST00000681106.1(transcript)|ensembl:ENST00000681721.1(transcript)|go:""GO:0005295""(""neutral L-amino acid:sodium symporter activity"")|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005326""(neurotransmitter transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015657""(""branched-chain amino acid:sodium symporter activity"")|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015824""(proline transport)|go:""GO:0016020""(membrane)|go:""GO:0035725""(sodium ion transmembrane transport)|interpro:IPR000175(""Sodium:neurotransmitter symporter"")|interpro:IPR002438(""Sodium:neurotransmitter symporter, orphan"")|interpro:IPR037272|interpro:IPR042934|mint:Q9H2J7|reactome:R-HSA-352230|reactome:R-HSA-442660"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:MubTClioe24j6+ldJKeHsmuzg1U9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P11586	intact:EBI-10726196	intact:EBI-709638|uniprotkb:Q86VC9|uniprotkb:Q9BVP5|uniprotkb:B2R5Y2|uniprotkb:G3V2B8|ensembl:ENSP00000498336.1|ensembl:ENSP00000498511.1|intact:EBI-21358459|uniprotkb:A0A024R652|uniprotkb:A0A384N5Y3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:c1tc_human(display_long)|uniprotkb:MTHFD1(gene name)|psi-mi:MTHFD1(display_short)|uniprotkb:MTHFC(gene name synonym)|uniprotkb:MTHFD(gene name synonym)|uniprotkb:Epididymis secretory sperm binding protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:658813""|dip:DIP-33682N|ensembl:ENSG00000100714.18(gene)|ensembl:ENST00000651537.1(transcript)|ensembl:ENST00000652337.1(transcript)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001843""(neural tube closure)|go:""GO:0004329""(formate-tetrahydrofolate ligase activity)|go:""GO:0004477""(methenyltetrahydrofolate cyclohydrolase activity)|go:""GO:0004486""(""methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity"")|go:""GO:0004487""(""methylenetetrahydrofolate dehydrogenase (NAD+) activity"")|go:""GO:0004488""(""methylenetetrahydrofolate dehydrogenase (NADP+) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006555""(methionine metabolic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0007507""(heart development)|go:""GO:0009069""(serine family amino acid metabolic process)|go:""GO:0009070""(serine family amino acid biosynthetic process)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0009152""(purine ribonucleotide biosynthetic process)|go:""GO:0009257""(10-formyltetrahydrofolate biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019346""(transsulfuration)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0048702""(embryonic neurocranium morphogenesis)|go:""GO:0048703""(embryonic viscerocranium morphogenesis)|go:""GO:0061053""(somite development)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR020867|interpro:IPR027417|interpro:IPR036291|interpro:IPR046346|mint:P11586|rcsb pdb:1A4I|rcsb pdb:1DIA|rcsb pdb:1DIB|rcsb pdb:1DIG|rcsb pdb:6ECP|rcsb pdb:6ECQ|rcsb pdb:6ECR|reactome:R-HSA-196757|refseq:NP_005947.3|panther:PTHR48099(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:6ZizfpjVcaL5WNxKXL7qJpw59PI9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8NHP6	intact:EBI-10726196	intact:EBI-2812848|uniprotkb:Q8N3H2|uniprotkb:Q8NA83|ensembl:ENSP00000369860.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001170946.1|refseq:NP_689794.1|ensembl:ENSG00000130150.12(gene)|ensembl:ENST00000380492.8(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0044232""(organelle membrane contact site)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|go:""GO:0140042""(lipid droplet formation)|go:""GO:0140284""(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|interpro:IPR053012|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|panther:PTHR46384(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9NX40	intact:EBI-10726196	intact:EBI-2683029|uniprotkb:C9K030|uniprotkb:Q9BZE8|uniprotkb:G8JLN7|ensembl:ENSP00000264312.7|ensembl:ENSP00000370882.3|ensembl:ENSP00000423002.1|ensembl:ENSP00000423909.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ocad1_human(display_long)|uniprotkb:OCIA(gene name synonym)|uniprotkb:Ovarian carcinoma immunoreactive antigen(gene name synonym)|uniprotkb:OCIAD1(gene name)|psi-mi:OCIAD1(display_short)|uniprotkb:ASRIJ(gene name synonym)|uniprotkb:Ovarian cancer immunoreactive antigen domain containing 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001073309.1|refseq:NP_001073311.2|refseq:NP_001073308.1|refseq:NP_001073310.1|refseq:NP_060300.1|refseq:XP_016863818.1|ensembl:ENSG00000109180.15(gene)|ensembl:ENST00000264312.12(transcript)|ensembl:ENST00000381473.7(transcript)|ensembl:ENST00000508293.5(transcript)|ensembl:ENST00000513391.2(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006897""(endocytosis)|go:""GO:0016020""(membrane)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|go:""GO:2000736""(regulation of stem cell differentiation)|interpro:IPR009764(Ovarian carcinoma immunoreactive antigen)|interpro:IPR040187|mint:Q9NX40|panther:PTHR13336(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:e3Ojv8LBlgj056bssUZjEC+MB+Q9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O00400	intact:EBI-10726196	intact:EBI-11135403|uniprotkb:D3DNK4|uniprotkb:B2R5Q2|ensembl:ENSP00000352456.3|ensembl:ENSP00000496241.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:acatn_human(display_long)|uniprotkb:SLC33A1(gene name)|psi-mi:SLC33A1(display_short)|uniprotkb:ACATN(gene name synonym)|uniprotkb:AT1(gene name synonym)|uniprotkb:Solute carrier family 33 member 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000169359.16(gene)|ensembl:ENST00000359479.7(transcript)|ensembl:ENST00000643144.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0008521""(acetyl-CoA transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0035348""(acetyl-CoA transmembrane transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0055085""(transmembrane transport)|interpro:IPR004752(AmpG-related permease)|interpro:IPR024371|interpro:IPR036259|mint:O00400|reactome:R-HSA-425397|reactome:R-HSA-5619061|refseq:NP_001177921.1|refseq:NP_004724.1|panther:PTHR12778(orthology-group)|efo:""Orphanet:171863""|efo:""Orphanet:300313"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:Gd55GgRVwnjfcEF2rsE1upo/+gc9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P61221	intact:EBI-10726196	intact:EBI-2510446|uniprotkb:Q6NR76|uniprotkb:O88793|uniprotkb:Q13181|uniprotkb:Q99K66|uniprotkb:Q13864|uniprotkb:Q96AL0|uniprotkb:Q96B10|ensembl:ENSP00000296577.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:abce1_human(display_long)|uniprotkb:ABCE1(gene name)|psi-mi:ABCE1(display_short)|uniprotkb:RLI(gene name synonym)|uniprotkb:RNASEL1(gene name synonym)|uniprotkb:RNASELI(gene name synonym)|uniprotkb:RNS4I(gene name synonym)|uniprotkb:RNase L inhibitor(gene name synonym)|uniprotkb:Ribonuclease 4 inhibitor(gene name synonym)|uniprotkb:2'-5'-oligoadenylate-binding protein(gene name synonym)|uniprotkb:HuHP68(gene name synonym)|uniprotkb:OK/SW-cl.40(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001035809.1|refseq:NP_002931.2|ensembl:ENSG00000164163.11(gene)|ensembl:ENST00000296577.9(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006415""(translational termination)|go:""GO:0006417""(regulation of translation)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017111""(ribonucleoside triphosphate phosphatase activity)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043273""(CTPase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0060698""(endoribonuclease inhibitor activity)|go:""GO:0060702""(negative regulation of endoribonuclease activity)|go:""GO:0072344""(rescue of stalled ribosome)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007209(Possible metal-binding region in RNase L inhibitor, RLI)|interpro:IPR013283(ABC transporter, ABCE)|interpro:IPR017871|interpro:IPR017896|interpro:IPR017900|interpro:IPR027417|interpro:IPR034348|mint:P61221|rcsb pdb:6ZME|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-8983711|reactome:R-HSA-909733|panther:PTHR19248(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:+6ykpRtI4p94M3TuoTzFBvdCsC09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9NZJ5	intact:EBI-10726196	intact:EBI-766076|uniprotkb:A0AVH2|uniprotkb:A0AVH1|uniprotkb:B2RCU9|uniprotkb:Q53QY0|uniprotkb:Q53SB1|uniprotkb:O95846|ensembl:ENSP00000307235.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:e2ak3_human(display_long)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)|uniprotkb:EIF2AK3(gene name)|psi-mi:EIF2AK3(display_short)|uniprotkb:PEK(gene name synonym)|uniprotkb:PERK(gene name synonym)|uniprotkb:Protein tyrosine kinase EIF2AK3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000172071.15(gene)|ensembl:ENST00000303236.9(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001503""(ossification)|go:""GO:0001525""(angiogenesis)|go:""GO:0002063""(chondrocyte development)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006983""(ER overload response)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010998""(regulation of translational initiation by eIF2 alpha phosphorylation)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030282""(bone mineralization)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031018""(endocrine pancreas development)|go:""GO:0031642""(negative regulation of myelination)|go:""GO:0032055""(negative regulation of translation in response to stress)|go:""GO:0032057""(negative regulation of translational initiation in response to stress)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036492""(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:""GO:0036499""(PERK-mediated unfolded protein response)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0045943""(positive regulation of transcription by RNA polymerase I)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0060734""(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:""GO:0070417""(cellular response to cold)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902235""(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990737""(response to manganese-induced endoplasmic reticulum stress)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050339|mint:Q9NZJ5|rcsb pdb:4G31|rcsb pdb:4G34|rcsb pdb:4M7I|rcsb pdb:4X7H|rcsb pdb:4X7J|rcsb pdb:4X7K|rcsb pdb:4X7L|rcsb pdb:4X7N|rcsb pdb:4X7O|rcsb pdb:4YZS|rcsb pdb:5SV7|rcsb pdb:7MF0|rcsb pdb:8EQ9|rcsb pdb:8EQD|rcsb pdb:8EQE|reactome:R-HSA-381042|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9755511|refseq:NP_004827.4|efo:""Orphanet:1667""|panther:PTHR11042(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:sjPIYQzmbvq1fvSgn0HR781yf9w9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9H0U3	intact:EBI-10726196	intact:EBI-2798816|uniprotkb:B2RAR4|uniprotkb:Q53G00|uniprotkb:Q8NBN6|uniprotkb:D3DTE3|ensembl:ENSP00000354649.6|ensembl:ENSP00000480732.1|uniprotkb:Q6P577	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:magt1_human(display_long)|uniprotkb:IAG2(gene name synonym)|uniprotkb:Implantation-associated protein(gene name synonym)|uniprotkb:MAGT1(gene name)|psi-mi:MAGT1(display_short)|uniprotkb:Magnesium transporter protein 1(gene name synonym)|uniprotkb:PSEC0084(orf name)|uniprotkb:UNQ628/PRO1244(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000102158.22(gene)|ensembl:ENST00000358075.11(transcript)|ensembl:ENST00000618282.5(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0015095""(magnesium ion transmembrane transporter activity)|go:""GO:0015693""(magnesium ion transport)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0050890""(cognition)|go:""GO:0055085""(transmembrane transport)|interpro:IPR021149|interpro:IPR036249|mint:Q9H0U3|rcsb pdb:6S7T|reactome:R-HSA-446203|reactome:R-HSA-5223345|reactome:R-HSA-6798695|reactome:R-HSA-9694548|refseq:NP_115497.4|efo:""Orphanet:317476""|panther:PTHR12692(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:M7/LTAlkuCCyeqlTlcJkfu2HU9k9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P29317	intact:EBI-10726196	intact:EBI-702104|uniprotkb:Q8N3Z2|ensembl:ENSP00000351209.5|uniprotkb:B5A968|intact:EBI-28989000	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:epha2_human(display_long)|uniprotkb:Tyrosine-protein kinase receptor ECK(gene name synonym)|uniprotkb:Epithelial cell kinase(gene name synonym)|uniprotkb:EPHA2(gene name)|psi-mi:EPHA2(display_short)|uniprotkb:ECK(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000142627.13(gene)|ensembl:ENST00000358432.8(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0002043""(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008288""(boss receptor activity)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009986""(cell surface)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0014028""(notochord formation)|go:""GO:0016477""(cell migration)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019838""(growth factor binding)|go:""GO:0021915""(neural tube development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0043235""(receptor complex)|go:""GO:0043535""(regulation of blood vessel endothelial cell migration)|go:""GO:0045296""(cadherin binding)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0046058""(cAMP metabolic process)|go:""GO:0046849""(bone remodeling)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048320""(axial mesoderm formation)|go:""GO:0048870""(cell motility)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0060035""(notochord cell development)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0060444""(branching involved in mammary gland duct morphogenesis)|go:""GO:0070160""(tight junction)|go:""GO:0070309""(lens fiber cell morphogenesis)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070848""(response to growth factor)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1901491""(negative regulation of lymphangiogenesis)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1904238""(pericyte cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034263|interpro:IPR036116|interpro:IPR050449|mint:P29317|rcsb pdb:1MQB|rcsb pdb:2E8N|rcsb pdb:2K9Y|rcsb pdb:2KSO|rcsb pdb:2X10|rcsb pdb:2X11|rcsb pdb:3C8X|rcsb pdb:3CZU|rcsb pdb:3FL7|rcsb pdb:3HEI|rcsb pdb:3HPN|rcsb pdb:3KKA|rcsb pdb:3MBW|rcsb pdb:3MX0|rcsb pdb:3SKJ|rcsb pdb:4P2K|rcsb pdb:4PDO|rcsb pdb:4TRL|rcsb pdb:5EK7|rcsb pdb:5I9U|rcsb pdb:5I9V|rcsb pdb:5I9W|rcsb pdb:5I9X|rcsb pdb:5I9Y|rcsb pdb:5I9Z|rcsb pdb:5IA0|rcsb pdb:5IA1|rcsb pdb:5IA2|rcsb pdb:5IA3|rcsb pdb:5IA4|rcsb pdb:5IA5|rcsb pdb:5NJZ|rcsb pdb:5NK0|rcsb pdb:5NK1|rcsb pdb:5NK2|rcsb pdb:5NK3|rcsb pdb:5NK4|rcsb pdb:5NK5|rcsb pdb:5NK6|rcsb pdb:5NK7|rcsb pdb:5NK8|rcsb pdb:5NK9|rcsb pdb:5NKA|rcsb pdb:5NKB|rcsb pdb:5NKC|rcsb pdb:5NKD|rcsb pdb:5NKE|rcsb pdb:5NKF|rcsb pdb:5NKG|rcsb pdb:5NKH|rcsb pdb:5NKI|rcsb pdb:5NZ9|rcsb pdb:6B9L|rcsb pdb:6F7M|rcsb pdb:6F7N|rcsb pdb:6FNF|rcsb pdb:6NK1|rcsb pdb:6FNG|rcsb pdb:6FNH|rcsb pdb:6HES|rcsb pdb:6HET|rcsb pdb:6HEU|rcsb pdb:6HEV|rcsb pdb:6HEW|rcsb pdb:6HEX|rcsb pdb:6HEY|rcsb pdb:6NJZ|rcsb pdb:6NK0|rcsb pdb:6NK2|rcsb pdb:6NKP|rcsb pdb:6Q7B|rcsb pdb:6Q7C|rcsb pdb:6Q7D|rcsb pdb:6Q7E|rcsb pdb:6Q7F|rcsb pdb:6Q7G|rcsb pdb:6RW2|rcsb pdb:7B7N|rcsb pdb:7CZE|rcsb pdb:7CZF|rcsb pdb:7KJA|rcsb pdb:7KJB|rcsb pdb:7KJC|rcsb pdb:8BIN|rcsb pdb:8BIO|rcsb pdb:8BK0|rcsb pdb:8BM8|rcsb pdb:8BOC|rcsb pdb:8BOD|rcsb pdb:8BOF|rcsb pdb:8BOG|rcsb pdb:8BOH|rcsb pdb:8BOI|rcsb pdb:8BOK|rcsb pdb:8BOM|rcsb pdb:8QQY|rcsb pdb:8T9B|rcsb pdb:8TRS|rcsb pdb:8TRT|rcsb pdb:8TRV|rcsb pdb:8TV1|rcsb pdb:8TV5|rcsb pdb:8XPV|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_004422.2|efo:""Orphanet:441447""|efo:""Orphanet:98991""|efo:""Orphanet:98993""|efo:""Orphanet:98994""|dip:DIP-96N|panther:PTHR24416(orthology-group)|ensembl:ENSP00000351209.5"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:9VFikLd4ftRmEyBpY0JHdpHINT09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8NFQ8	intact:EBI-10726196	intact:EBI-524567|ensembl:ENSP00000356584.3|ensembl:ENSP00000477486.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:toip2_human(display_long)|uniprotkb:Lumenal domain-like LAP1(gene name synonym)|uniprotkb:TOR1AIP2(gene name)|psi-mi:TOR1AIP2(display_short)|uniprotkb:LULL1(gene name synonym)|uniprotkb:IFRG15(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000169905.13(gene)|ensembl:ENST00000367612.7(transcript)|ensembl:ENST00000609928.6(transcript)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0051117""(ATPase binding)|go:""GO:0061024""(membrane organization)|go:""GO:0090435""(protein localization to nuclear envelope)|interpro:IPR008662(Lamina-associated polypeptide 1C)|interpro:IPR038599|interpro:IPR046753|interpro:IPR046754|mint:Q8NFQ8|rcsb pdb:5J1S|rcsb pdb:5J1T|refseq:XP_005244996.1|refseq:XP_016855963.1|refseq:XP_016855964.1|refseq:NP_001186189.1|refseq:NP_659471.1|panther:PTHR18843(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:HjY3sLjzR1jmKq2EqIKRvY3GxKc9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9NZ01	intact:EBI-10726196	intact:EBI-2877718|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55|ensembl:ENSP00000215567.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000099797.15(gene)|ensembl:ENST00000215567.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006665""(sphingolipid metabolic process)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0017099""(very-long-chain fatty acyl-CoA dehydrogenase activity)|go:""GO:0030497""(fatty acid elongation)|go:""GO:0035338""(long-chain fatty-acyl-CoA biosynthetic process)|go:""GO:0042761""(very long-chain fatty acid biosynthetic process)|go:""GO:0102758""(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|interpro:IPR049127|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_001308099.1|refseq:NP_612510.1|efo:""Orphanet:88616""|panther:PTHR10556(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O15260	intact:EBI-10726196	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|uniprotkb:B7Z6A4|ensembl:ENSP00000361057.3|ensembl:ENSP00000486049.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_149351.1|refseq:NP_001267718.1|refseq:NP_001267721.1|ensembl:ENSG00000148248.14(gene)|ensembl:ENSG00000280951.3(gene)|ensembl:ENST00000371989.8(transcript)|ensembl:ENST00000629578.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0010638""(positive regulation of organelle organization)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032368""(regulation of lipid transport)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:0097020""(COPII receptor activity)|go:""GO:0140353""(lipid export from cell)|interpro:IPR002995(Surfeit locus 4)|interpro:IPR045214|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|panther:PTHR23427(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P30101	intact:EBI-10726196	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000167004.14(gene)|ensembl:ENST00000300289.10(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004629""(phospholipase C activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0009986""(cell surface)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061779""(Tapasin-ERp57 complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|rcsb pdb:7QNG|rcsb pdb:7QPD|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|refseq:NP_005304.3|dip:DIP-29132N|panther:PTHR18929(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9Y2H6	intact:EBI-10726196	intact:EBI-2810266|uniprotkb:Q6EVH4|uniprotkb:Q6N020|uniprotkb:B4DYG1|uniprotkb:Q5JVF8|uniprotkb:Q5HYC9|uniprotkb:Q6ZME4|uniprotkb:Q6P9D5|uniprotkb:Q6EVH3|uniprotkb:Q5JVF9|uniprotkb:Q9H1W1|ensembl:ENSP00000417257.1|ensembl:ENSP00000441831.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:fnd3a_human(display_long)|uniprotkb:FNDC3A(gene name)|psi-mi:FNDC3A(display_short)|uniprotkb:FNDC3(gene name synonym)|uniprotkb:HUGO(gene name synonym)|uniprotkb:KIAA0970(gene name synonym)|uniprotkb:Human gene expressed in odontoblasts(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001073141.1|refseq:NP_055738.3|refseq:XP_011533299.1|refseq:NP_001265367.1|ensembl:ENSG00000102531.16(gene)|ensembl:ENST00000492622.6(transcript)|ensembl:ENST00000541916.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007286""(spermatid development)|go:""GO:0009566""(fertilization)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060009""(Sertoli cell development)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR050617|mint:Q9Y2H6|rcsb pdb:1WK0|rcsb pdb:1X3D|rcsb pdb:1X4X|rcsb pdb:1X5X|rcsb pdb:2CRM|rcsb pdb:2CRZ|refseq:XP_016875929.1|refseq:XP_016875930.1|refseq:XP_016875931.1|panther:PTHR24099(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:7gFZgxAfa590PH85SnEF3oeSNSI9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P50454	intact:EBI-10726196	intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|intact:EBI-25629313|ensembl:ENSP00000350894.4|ensembl:ENSP00000434412.1|ensembl:ENSP00000434657.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000149257.16(gene)|ensembl:ENST00000358171.8(transcript)|ensembl:ENST00000524558.5(transcript)|ensembl:ENST00000533603.5(transcript)|go:""GO:0003433""(chondrocyte development involved in endochondral bone morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0032964""(collagen biosynthetic process)|go:""GO:0045121""(membrane raft)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051604""(protein maturation)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|refseq:NP_001193943.1|refseq:NP_001226.2|refseq:XP_011543629.1|efo:""Orphanet:216812""|panther:PTHR11461(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96SK2	intact:EBI-10726196	intact:EBI-10963859|uniprotkb:Q6PF00|uniprotkb:Q96SL6|uniprotkb:A4D1L1|uniprotkb:Q8NCH3|uniprotkb:Q49A50|ensembl:ENSP00000380747.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tm209_human(display_long)|uniprotkb:TMEM209(gene name)|psi-mi:TMEM209(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001288092.1|refseq:NP_116231.2|refseq:XP_005250712.1|refseq:XP_011514948.1|ensembl:ENSG00000146842.17(gene)|ensembl:ENST00000397622.7(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0016020""(membrane)|interpro:IPR019176|mint:Q96SK2|panther:PTHR21780(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:LJ052UMkTP09EJVErI5qnsGxmJs9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9HD26	intact:EBI-10726196	intact:EBI-349832|uniprotkb:A6NM30|uniprotkb:Q59FS4|uniprotkb:Q969U8|ensembl:ENSP00000357484.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:gopc_human(display_long)|uniprotkb:CAL(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000047932.14(gene)|ensembl:ENST00000368498.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0010360""(negative regulation of anion channel activity)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030425""(dendrite)|go:""GO:0030660""(Golgi-associated vesicle membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045176""(apical protein localization)|go:""GO:0140313""(molecular sequestering activity)|go:""GO:2000009""(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR038879|mint:Q9HD26|rcsb pdb:2DC2|rcsb pdb:2LOB|rcsb pdb:4E34|rcsb pdb:4E35|rcsb pdb:4JOE|rcsb pdb:4JOF|rcsb pdb:4JOG|rcsb pdb:4JOH|rcsb pdb:4JOJ|rcsb pdb:4JOK|rcsb pdb:4JOP|rcsb pdb:4JOR|rcsb pdb:4K6Y|rcsb pdb:4K72|rcsb pdb:4K75|rcsb pdb:4K76|rcsb pdb:4K78|rcsb pdb:4NMO|rcsb pdb:4NMP|rcsb pdb:4NMQ|rcsb pdb:4NMR|rcsb pdb:4NMS|rcsb pdb:4NMT|rcsb pdb:4NMV|rcsb pdb:4Q6H|rcsb pdb:4Q6S|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6OV7|rcsb pdb:6V84|rcsb pdb:6XNJ|rcsb pdb:7JZO|rcsb pdb:7JZP|rcsb pdb:7JZQ|rcsb pdb:7JZR|reactome:R-HSA-5627083|reactome:R-HSA-9013406|refseq:NP_001017408.1|refseq:NP_065132.1|panther:PTHR16528(orthology-group)|efo:""Orphanet:171709"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:bXzu5wvJifZwB+Q52cgC4tZQl/k9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q92783	intact:EBI-10726196	intact:EBI-752333|ensembl:ENSP00000366746.3|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000136738.15(gene)|ensembl:ENST00000377524.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0016236""(macroautophagy)|go:""GO:0031901""(early endosome membrane)|go:""GO:0033565""(ESCRT-0 complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0090148""(membrane fission)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903551""(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|interpro:IPR047492|interpro:IPR047528|interpro:IPR050670|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|refseq:NP_003464.1|dip:DIP-37761N|panther:PTHR45929(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9UBM7	intact:EBI-10726196	intact:EBI-1054468|uniprotkb:O60492|uniprotkb:O60717|uniprotkb:B2R6Z2|ensembl:ENSP00000347717.4|ensembl:ENSP00000384739.2|ensembl:ENSP00000435668.2|ensembl:ENSP00000435707.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	"psi-mi:dhcr7_human(display_long)|uniprotkb:""Sterol Delta(7)-reductase""(gene name synonym)|uniprotkb:DHCR7(gene name)|psi-mi:DHCR7(display_short)|uniprotkb:D7SR(gene name synonym)|uniprotkb:Delta7-sterol reductase(gene name synonym)|uniprotkb:Sterol reductase SR-2(gene name synonym)|uniprotkb:Cholesterol-5,6-epoxide hydrolase subunit DHCR7(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:818""|ensembl:ENSG00000172893.18(gene)|ensembl:ENST00000355527.8(transcript)|ensembl:ENST00000407721.6(transcript)|ensembl:ENST00000525346.6(transcript)|ensembl:ENST00000526780.6(transcript)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0033489""(cholesterol biosynthetic process via desmosterol)|go:""GO:0033490""(cholesterol biosynthetic process via lathosterol)|go:""GO:0047598""(7-dehydrocholesterol reductase activity)|go:""GO:0050661""(NADP binding)|go:""GO:0160020""(positive regulation of ferroptosis)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR018083|mint:Q9UBM7|reactome:R-HSA-2426168|reactome:R-HSA-6807047|reactome:R-HSA-6807062|refseq:NP_001157289.1|refseq:NP_001351.2|panther:PTHR21257(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:op53bBpGaOM0Ysy4Bn5q6qXcKgI9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9BU23	intact:EBI-10726196	intact:EBI-10298556|uniprotkb:Q96C62|uniprotkb:Q13392|uniprotkb:Q8WU74|uniprotkb:Q6ZNR2|uniprotkb:A6NEZ0|ensembl:ENSP00000424381.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:lmf2_human(display_long)|uniprotkb:LMF2(gene name)|psi-mi:LMF2(display_short)|uniprotkb:TMEM112B(gene name synonym)|uniprotkb:TMEM153(gene name synonym)|uniprotkb:Transmembrane protein 112B(gene name synonym)|uniprotkb:Transmembrane protein 153(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_149977.2|refseq:XP_005262012.1|ensembl:ENSG00000100258.18(gene)|ensembl:ENST00000474879.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0051604""(protein maturation)|interpro:IPR009613(Protein of unknown function DUF1222)|mint:Q9BU23|reactome:R-HSA-8963889|panther:PTHR14463(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:xI+AYnn8Oj5BWzpTBzJi4K83wck9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9HCU5	intact:EBI-10726196	intact:EBI-2553896|uniprotkb:Q9UH94|uniprotkb:Q53SZ8|ensembl:ENSP00000260643.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:sec12_human(display_long)|uniprotkb:SEC12(gene name synonym)|uniprotkb:PREB(gene name)|psi-mi:PREB(display_short)|uniprotkb:Prolactin regulatory element-binding protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_037520.1|refseq:NP_001317414.1|refseq:NP_001317415.1|ensembl:ENSG00000138073.14(gene)|ensembl:ENST00000260643.7(transcript)|go:""GO:0003400""(regulation of COPII vesicle coating)|go:""GO:0003677""(DNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0016020""(membrane)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0051020""(GTPase binding)|go:""GO:0070971""(endoplasmic reticulum exit site)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR045260|mint:Q9HCU5|rcsb pdb:5TF2|reactome:R-HSA-204005|reactome:R-HSA-381038|reactome:R-HSA-5694530|panther:PTHR23284(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:3xjABrP1KtfZUMb/BSbe8ZN6dJ49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P05023	intact:EBI-10726196	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|ensembl:ENSP00000295598.5|intact:EBI-10963133	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR43294(orthology-group)|ensembl:ENSG00000163399.16(gene)|ensembl:ENST00000295598.10(transcript)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0005391""(""P-type sodium:potassium-exchanging transporter activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0007231""(osmosensory signaling pathway)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016791""(phosphatase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030315""(T-tubule)|go:""GO:0030424""(axon)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031090""(organelle membrane)|go:""GO:0031402""(sodium ion binding)|go:""GO:0031947""(negative regulation of glucocorticoid biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0045823""(positive regulation of heart contraction)|go:""GO:0045989""(positive regulation of striated muscle contraction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060342""(photoreceptor inner segment membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086009""(membrane repolarization)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903416""(response to glycoside)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990239""(steroid hormone binding)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|interpro:IPR050510|mint:P05023|rcsb pdb:7E1Z|rcsb pdb:7E20|rcsb pdb:7E21|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|efo:""Orphanet:521414""|efo:""Orphanet:564178"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O43399	intact:EBI-10726196	intact:EBI-782604|uniprotkb:Q5U0E0|uniprotkb:Q5JWU6|uniprotkb:Q9H3Z6|intact:EBI-1043547|uniprotkb:O43398|uniprotkb:Q5JWU5|uniprotkb:Q5JWU8|uniprotkb:E1P5G7|uniprotkb:B4DPJ6|ensembl:ENSP00000343547.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tpd54_human(display_long)|uniprotkb:Tumor protein D52-like 2(gene name synonym)|uniprotkb:TPD52L2(gene name)|psi-mi:TPD52L2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001230821.1|refseq:NP_003279.2|refseq:NP_955393.1|refseq:NP_955395.1|refseq:NP_955394.1|refseq:NP_955392.1|ensembl:ENSG00000101150.18(gene)|ensembl:ENST00000346249.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|interpro:IPR012341(Six-hairpin glycosidase)|mint:O43399|panther:PTHR19307(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:asqRlZnmqIzXCJ5TAHjxKcj046g9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9NXE4	intact:EBI-10726196	intact:EBI-372102|ensembl:ENSP00000386531.1|ensembl:ENSP00000517885.1|uniprotkb:Q6FI76|uniprotkb:Q6P1P7|uniprotkb:Q6ZT43|uniprotkb:Q9H0M2|uniprotkb:Q9NW20|uniprotkb:Q9NWL2|uniprotkb:Q9P2C9|uniprotkb:B4DWK7|uniprotkb:E9PCE6|intact:EBI-1058838|uniprotkb:B4DRB8|uniprotkb:E7ESA2|uniprotkb:B4DM23|uniprotkb:B4DQ31|uniprotkb:B4E0L6|uniprotkb:B1PBA3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:nsma3_human(display_long)|uniprotkb:SKNY(gene name synonym)|uniprotkb:SMPD4(gene name)|psi-mi:SMPD4(display_short)|uniprotkb:Neutral sphingomyelinase 3(gene name synonym)|uniprotkb:Neutral sphingomyelinase III(gene name synonym)|uniprotkb:KIAA1418(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000136699.20(gene)|ensembl:ENSG00000292130.1(gene)|ensembl:ENST00000409031.5(transcript)|ensembl:ENST00000709809.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004767""(sphingomyelin phosphodiesterase activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0006685""(sphingomyelin catabolic process)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0042383""(sarcolemma)|go:""GO:0046475""(glycerophospholipid catabolic process)|go:""GO:0046513""(ceramide biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050290""(sphingomyelin phosphodiesterase D activity)|go:""GO:0071356""(cellular response to tumor necrosis factor)|interpro:IPR024129|mint:Q9NXE4|reactome:R-HSA-9840310|refseq:NP_001164554.1|refseq:NP_060221.2|refseq:NP_060421.2|refseq:XP_011509747.1|refseq:XP_016859937.1|refseq:XP_016859938.1|panther:PTHR12988(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:/OGzQcEQfrn7jgedtceXIuns7449606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9NW15	intact:EBI-10726196	intact:EBI-11349452|ensembl:ENSP00000292246.3|uniprotkb:B7WP12|uniprotkb:A8K8K3|uniprotkb:Q8IXX9|uniprotkb:C9JHS1|uniprotkb:B4DNK2|uniprotkb:B3KY93|uniprotkb:B4DJ83|uniprotkb:B3KTZ1|uniprotkb:A8MV74	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ano10_human(display_long)|uniprotkb:ANO10(gene name)|psi-mi:ANO10(display_short)|uniprotkb:TMEM16K(gene name synonym)|uniprotkb:Transmembrane protein 16K(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000160746.13(gene)|ensembl:ENST00000292246.8(transcript)|go:""GO:0005227""(calcium-activated cation channel activity)|go:""GO:0005229""(intracellularly calcium-gated chloride channel activity)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:1902476""(chloride transmembrane transport)|interpro:IPR007632(Protein of unknown function DUF590)|interpro:IPR049452|mint:Q9NW15|rcsb pdb:5OC9|rcsb pdb:6R65|rcsb pdb:6R7X|rcsb pdb:6R7Y|rcsb pdb:6R7Z|reactome:R-HSA-2672351|reactome:R-HSA-9733458|refseq:NP_001191760.1|refseq:NP_001191761.1|refseq:NP_001191762.1|refseq:NP_001191763.1|refseq:NP_001333392.1|refseq:NP_001333393.1|refseq:NP_001333394.1|refseq:NP_001333395.1|refseq:NP_001333396.1|refseq:NP_001333397.1|refseq:NP_001333398.1|refseq:NP_060545.3|refseq:XP_016862211.1|panther:PTHR12308(orthology-group)|efo:""Orphanet:284289"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:XRfkrBqltkpquCUp5CyaWn7pKJo9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q16795	intact:EBI-10726196	intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_004993.1|dip:DIP-38526N|ensembl:ENSG00000139180.11(gene)|ensembl:ENST00000266544.10(transcript)|go:""GO:0003954""(NADH dehydrogenase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006120""(mitochondrial electron transport, NADH to ubiquinone)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0006814""(sodium ion transport)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008137""(""NADH dehydrogenase (ubiquinone) activity"")|go:""GO:0009060""(aerobic respiration)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032981""(mitochondrial respiratory chain complex I assembly)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045271""(respiratory chain complex I)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|interpro:IPR051207|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|panther:PTHR12126(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q6P996	intact:EBI-10726196	intact:EBI-1049813|uniprotkb:Q4F6X7|uniprotkb:O00236|uniprotkb:Q6PID7|uniprotkb:Q86YF1|uniprotkb:Q8N4Q9|uniprotkb:Q8TBS5|ensembl:ENSP00000379691.4|ensembl:ENSP00000484595.1|uniprotkb:B4DR55|uniprotkb:B4DSL3|uniprotkb:E7EMH5|uniprotkb:E7EPL4|uniprotkb:H3BNZ1|intact:EBI-10982185	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:pdxd1_human(display_long)|uniprotkb:PDXDC1(gene name)|psi-mi:PDXDC1(display_short)|uniprotkb:KIAA0251(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001272373.1|refseq:NP_001272374.1|refseq:NP_001272376.1|refseq:NP_001272377.1|refseq:NP_001272379.1|refseq:NP_055842.2|refseq:XP_006725291.1|refseq:XP_006726663.1|refseq:XP_006725288.1|refseq:XP_006726660.1|ensembl:ENSG00000179889.21(gene)|ensembl:ENSG00000275498.5(gene)|ensembl:ENST00000396410.9(transcript)|ensembl:ENST00000618389.4(transcript)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0016831""(carboxy-lyase activity)|go:""GO:0019752""(carboxylic acid metabolic process)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR050477|interpro:IPR055102|interpro:IPR055103|mint:Q6P996|panther:PTHR42735(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:59DMMTVwe8bQCfqtUSZcV+nhEDQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9BUF5	intact:EBI-10726196	intact:EBI-356735|uniprotkb:Q9HA42|uniprotkb:B3KM76|ensembl:ENSP00000318697.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:tbb6_human(display_long)|uniprotkb:TUBB6(gene name)|psi-mi:TUBB6(display_short)|uniprotkb:Tubulin beta class V(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_115914.1|refseq:NP_001290453.1|refseq:NP_001290454.1|refseq:NP_001290455.1|refseq:NP_001290456.1|refseq:NP_001290457.1|refseq:NP_001290458.1|refseq:NP_001290459.1|ensembl:ENSG00000176014.13(gene)|ensembl:ENST00000317702.10(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0003924""(GTPase activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005874""(microtubule)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0045171""(intercellular bridge)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072686""(mitotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BUF5|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9833482|panther:PTHR11588(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:/IC9o8wSAOu+lNgq44Qqu5hEof49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96CS3	intact:EBI-10726196	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942.6	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:faf2_human(display_long)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_055428.1|ensembl:ENSG00000113194.13(gene)|ensembl:ENST00000261942.7(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005811""(lipid droplet)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034098""(VCP-NPL4-UFD1 AAA ATPase complex)|go:""GO:0034389""(lipid droplet organization)|go:""GO:0035473""(lipase binding)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035617""(stress granule disassembly)|go:""GO:0036503""(ERAD pathway)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0055102""(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|interpro:IPR049483|interpro:IPR050730|interpro:IPR054109|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|dip:DIP-46261N|panther:PTHR23322(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96N66	intact:EBI-10726196	intact:EBI-6116499|uniprotkb:A9C4B6|uniprotkb:B0V3I5|uniprotkb:B4DQ87|uniprotkb:Q05DF0|uniprotkb:Q7L5N2|uniprotkb:Q99908|uniprotkb:Q9BPV2|uniprotkb:Q9BRE9|ensembl:ENSP00000245615.1|ensembl:ENSP00000478041.1|ensembl:ENSP00000478088.1|ensembl:ENSP00000478965.1|ensembl:ENSP00000481455.1|ensembl:ENSP00000482252.1|ensembl:ENSP00000482625.1|ensembl:ENSP00000484199.1|ensembl:ENSP00000484933.1|ensembl:ENSP00000484954.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:mboa7_human(display_long)|uniprotkb:OACT7(gene name synonym)|uniprotkb:MBOAT7(gene name)|psi-mi:MBOAT7(display_short)|uniprotkb:BB1(gene name synonym)|uniprotkb:LENG4(gene name synonym)|uniprotkb:1-acylglycerophosphatidylinositol O-acyltransferase(gene name synonym)|uniprotkb:Bladder and breast carcinoma-overexpressed gene 1 protein(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 4(gene name synonym)|uniprotkb:Lysophosphatidylinositol acyltransferase(gene name synonym)|uniprotkb:Membrane-bound O-acyltransferase domain-containing protein 7(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:88616""|ensembl:ENSG00000125505.17(gene)|ensembl:ENSG00000273592.4(gene)|ensembl:ENSG00000274194.4(gene)|ensembl:ENSG00000275118.4(gene)|ensembl:ENSG00000276935.4(gene)|ensembl:ENSG00000277025.4(gene)|ensembl:ENSG00000277733.4(gene)|ensembl:ENSG00000277923.4(gene)|ensembl:ENSG00000278322.4(gene)|ensembl:ENSG00000278519.4(gene)|ensembl:ENST00000245615.6(transcript)|ensembl:ENST00000613506.4(transcript)|ensembl:ENST00000613746.4(transcript)|ensembl:ENST00000615453.4(transcript)|ensembl:ENST00000617012.4(transcript)|ensembl:ENST00000618378.4(transcript)|ensembl:ENST00000619842.4(transcript)|ensembl:ENST00000619855.4(transcript)|ensembl:ENST00000621612.4(transcript)|ensembl:ENST00000621875.4(transcript)|go:""GO:0003841""(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0008374""(O-acyltransferase activity)|go:""GO:0016020""(membrane)|go:""GO:0021591""(ventricular system development)|go:""GO:0021819""(layer formation in cerebral cortex)|go:""GO:0030258""(lipid modification)|go:""GO:0036149""(phosphatidylinositol acyl-chain remodeling)|go:""GO:0036151""(phosphatidylcholine acyl-chain remodeling)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0047144""(2-acylglycerol-3-phosphate O-acyltransferase activity)|go:""GO:0071617""(lysophospholipid acyltransferase activity)|go:""GO:0090207""(regulation of triglyceride metabolic process)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR049941|mint:Q96N66|rcsb pdb:8ERC|reactome:R-HSA-1482922|refseq:NP_001139528.1|refseq:NP_001139554.1|refseq:NP_001139555.1|refseq:NP_077274.3|refseq:XP_011525601.1|refseq:XP_011525602.1|panther:PTHR13906(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:NdxbWV63CtA/flzPPhYadlBQksU9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P78406	intact:EBI-10726196	intact:EBI-724495|uniprotkb:O15306|uniprotkb:Q3SYL7|uniprotkb:Q5TCH8|uniprotkb:Q6V708|uniprotkb:Q9H100|uniprotkb:Q9NQM6|uniprotkb:A8K882|ensembl:ENSP00000360286.2|ensembl:ENSP00000379181.2|ensembl:ENSP00000379182.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:rae1l_human(display_long)|uniprotkb:mRNA-associated protein mrnp 41(gene name synonym)|uniprotkb:Rae1 protein homolog(gene name synonym)|uniprotkb:RAE1(gene name)|psi-mi:RAE1(display_short)|uniprotkb:MRNP41(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001015885.1|refseq:NP_003601.1|refseq:XP_005260639.2|refseq:XP_005260640.1|refseq:XP_011527390.1|refseq:XP_011527391.1|ensembl:ENSG00000101146.13(gene)|ensembl:ENST00000371242.6(transcript)|ensembl:ENST00000395840.6(transcript)|ensembl:ENST00000395841.7(transcript)|go:""GO:0000972""(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:""GO:0001650""(fibrillar center)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0008017""(microtubule binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0051301""(cell division)|go:""GO:0060236""(regulation of mitotic spindle organization)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0097431""(mitotic spindle pole)|interpro:IPR001680(WD40 repeat)|rcsb pdb:7VPH|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P78406|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:7F60|rcsb pdb:7F90|rcsb pdb:7VPG|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9705671|dip:DIP-41063N|panther:PTHR10971(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:JK4Y5p3WUcHFXBXyhhqCnDnG49c9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P53007	intact:EBI-10726196	intact:EBI-359163|uniprotkb:Q9BSK6|uniprotkb:A8K8E8|ensembl:ENSP00000215882.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:txtp_human(display_long)|uniprotkb:SLC25A1(gene name)|psi-mi:SLC25A1(display_short)|uniprotkb:SLC20A3(gene name synonym)|uniprotkb:Citrate transport protein(gene name synonym)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 1(gene name synonym)|uniprotkb:Mitochondrial citrate carrier(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:356978""|efo:""Orphanet:98914""|ensembl:ENSG00000100075.10(gene)|ensembl:ENST00000215882.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006843""(mitochondrial citrate transmembrane transport)|go:""GO:0015137""(citrate transmembrane transporter activity)|go:""GO:0015142""(tricarboxylic acid transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071913""(citrate secondary active transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|interpro:IPR049563|mint:P53007|reactome:R-HSA-428643|refseq:NP_005975.1|panther:PTHR45788(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:MB0RrMAQme4F8M4IivU1AqUxlgA9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9UNK0	intact:EBI-10726196	intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_004844.1|ensembl:ENSG00000170310.15(gene)|ensembl:ENST00000306357.9(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0012505""(endomembrane system)|go:""GO:0019869""(chloride channel inhibitor activity)|go:""GO:0019905""(syntaxin binding)|go:""GO:0031201""(SNARE complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048278""(vesicle docking)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|interpro:IPR045242|mint:Q9UNK0|dip:DIP-47274N|panther:PTHR19957(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:jdsUOdy99aWRb94ndPtawff7z/o9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96QT4	intact:EBI-10726196	intact:EBI-8042878|uniprotkb:Q86VJ4|uniprotkb:Q8NBW2|uniprotkb:Q6ZMF5|uniprotkb:Q9NXQ2|uniprotkb:Q9BXB2|intact:MINT-2815126|intact:EBI-28970210|ensembl:ENSP00000495860.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:trpm7_human(display_long)|uniprotkb:TRPM7(gene name)|psi-mi:TRPM7(display_short)|uniprotkb:CHAK1(gene name synonym)|uniprotkb:LTRPC7(gene name synonym)|uniprotkb:Long transient receptor potential channel 7(gene name synonym)|uniprotkb:Channel-kinase 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:140957""|efo:""Orphanet:90020""|panther:PTHR13800(orthology-group)|ensembl:ENSG00000092439.16(gene)|ensembl:ENST00000646667.1(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0003779""(actin binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005385""(zinc ion transmembrane transporter activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006829""(zinc ion transport)|go:""GO:0010960""(magnesium ion homeostasis)|go:""GO:0010961""(intracellular magnesium ion homeostasis)|go:""GO:0015095""(magnesium ion transmembrane transporter activity)|go:""GO:0015693""(magnesium ion transport)|go:""GO:0016340""(calcium-dependent cell-matrix adhesion)|go:""GO:0017022""(myosin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055080""(monoatomic cation homeostasis)|go:""GO:0070266""(necroptotic process)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0098655""(monoatomic cation transmembrane transport)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR004166(MHCK/EF2 kinase)|interpro:IPR005821(Ion transport)|interpro:IPR011009(Protein kinase-like)|interpro:IPR029601|interpro:IPR032415|interpro:IPR037162|interpro:IPR041491|interpro:IPR050927|mint:Q96QT4|reactome:R-HSA-3295583|refseq:NP_001288141.1|refseq:NP_060142.3"	-	-	"function:""\""Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1)\""""|comment:mint|function:""\""Defects in TRPM7 influences susceptibility to amyotrophic lateral sclerosis-parkinsonism/dementia complex type 1 [MIM:105500]; also called amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam or Guam disease. Amyotrophic lateral sclerosis-parkinsonism/dementia complex type 1 is a neurodengenerative disorder with unusually high incidence among the Chamorro people of the Western Pacific Islands of Guam. Both amyotrophic lateral sclerosis and parkinsonism-dementia are chronic, progressive, and uniformly fatal disorders in this population. Both diseases are known to occur in the same kindred, the same sibship, and even the same individual\"""""	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:IS+9n5E30il3gw+TXN1nbwV4ORk9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P35613	intact:EBI-10726196	intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|ensembl:ENSG00000172270.22(gene)|ensembl:ENST00000333511.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0003407""(neural retina development)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007566""(embryo implantation)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045494""(photoreceptor cell maintenance)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0046689""(response to mercury ion)|go:""GO:0046697""(decidualization)|go:""GO:0051591""(response to cAMP)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:1904466""(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:3QR2|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|rcsb pdb:7DAA|rcsb pdb:7DCE|rcsb pdb:7XY8|rcsb pdb:8XEJ|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-9749641|refseq:XP_016882662.1|dip:DIP-50310N|panther:PTHR10075(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P61106	intact:EBI-10726196	intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946.4|ensembl:ENSP00000515613.1|ensembl:ENSP00000515614.1|intact:EBI-21352994	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_057406.2|ensembl:ENSG00000119396.12(gene)|ensembl:ENST00000373840.9(transcript)|ensembl:ENST00000703999.1(transcript)|ensembl:ENST00000704000.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001845""(phagolysosome assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005795""(Golgi stack)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019003""(GDP binding)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0031489""(myosin V binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0042175""(nuclear outer membrane-endoplasmic reticulum membrane network)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090382""(phagosome maturation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|interpro:IPR050209|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O95782	intact:EBI-10726196	intact:EBI-353552|uniprotkb:Q96CI7|uniprotkb:Q96PP6|uniprotkb:Q96PP7|uniprotkb:Q9H070|ensembl:ENSP00000351926.4|intact:EBI-28973302	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ap2a1_human(display_long)|uniprotkb:AP2A1(gene name)|psi-mi:AP2A1(display_short)|uniprotkb:ADTAA(gene name synonym)|uniprotkb:CLAPA1(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_055018.2|refseq:NP_570603.2|ensembl:ENSG00000196961.13(gene)|ensembl:ENST00000359032.10(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0006897""(endocytosis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030130""(clathrin coat of trans-Golgi network vesicle)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0032433""(filopodium tip)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098843""(postsynaptic endocytic zone)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900126""(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR050840|mint:O95782|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|dip:DIP-33164N|panther:PTHR22780(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:egkaIAhvIi1FqNr+8KEFeJaYZcc9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q86UP2	intact:EBI-10726196	intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3|ensembl:ENSP00000378725.3|ensembl:ENSP00000432149.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001072989.1|refseq:NP_004977.2|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|ensembl:ENSG00000126777.18(gene)|ensembl:ENST00000395314.8(transcript)|ensembl:ENST00000459737.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0045296""(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:XP_011535053.1|refseq:XP_011535055.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N|panther:PTHR18864(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P13667	intact:EBI-10726196	intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055983|imex:IM-29147-9	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_004902.1|ensembl:ENSG00000155660.11(gene)|ensembl:ENST00000652332.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006457""(protein folding)|go:""GO:0009306""(protein secretion)|go:""GO:0009986""(cell surface)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0061077""(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV|panther:PTHR18929(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606	intact-crc:0865CF2C7762FE0B|rigid:AH8jKW+6WNlehdM2+FWQX9BVuOM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q969F9	uniprotkb:A0A0H3NFP4	intact:EBI-16781620|uniprotkb:A8K6G6|uniprotkb:Q8WTV6|uniprotkb:Q96AP1|uniprotkb:Q96MR3|uniprotkb:Q9H608|ensembl:ENSP00000296051.2	intact:EBI-27055396	psi-mi:hps3_human(display_long)|uniprotkb:Hermansky-Pudlak syndrome 3 protein(gene name synonym)|uniprotkb:HPS3(gene name)|psi-mi:HPS3(display_short)	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:""MI:0096""(pull down)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27056484|imex:IM-29147-31	intact-miscore:0.47	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:231512""|ensembl:ENSG00000163755.9(gene)|ensembl:ENST00000296051.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0031084""(BLOC-2 complex)|go:""GO:0046907""(intracellular transport)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:1903232""(melanosome assembly)|interpro:IPR017216(BLOC-2 complex, Hps3 subunit)|interpro:IPR029437|interpro:IPR029438|mint:Q969F9|refseq:NP_001295187.1|refseq:NP_115759.2|panther:PTHR28633(orthology-group)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	-	-	figure legend:F3B-E SF7A-B SF6|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2021/07/28	2024/11/14	rogid:v6pL0ap1hoLI7VbA0j1M2ZEwlgw9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	intact-crc:2FBBF600BC0368AF|rigid:9tD1w70K8WKDOc9m4Dz6U+JQsq4	false	red fluorescent protein tag:n-n	green fluorescent protein tag:c-c|necessary binding region:41-100,271-324|mutation with no effect:201-201|mutation with no effect:130-130|mutation with no effect:201-201,130-130	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q969F9	uniprotkb:A0A0H3NFP4	intact:EBI-16781620|uniprotkb:A8K6G6|uniprotkb:Q8WTV6|uniprotkb:Q96AP1|uniprotkb:Q96MR3|uniprotkb:Q9H608|ensembl:ENSP00000296051.2	intact:EBI-27055396	psi-mi:hps3_human(display_long)|uniprotkb:Hermansky-Pudlak syndrome 3 protein(gene name synonym)|uniprotkb:HPS3(gene name)|psi-mi:HPS3(display_short)	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:""MI:0096""(pull down)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27056580|imex:IM-29147-11	intact-miscore:0.47	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:231512""|ensembl:ENSG00000163755.9(gene)|ensembl:ENST00000296051.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0031084""(BLOC-2 complex)|go:""GO:0046907""(intracellular transport)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:1903232""(melanosome assembly)|interpro:IPR017216(BLOC-2 complex, Hps3 subunit)|interpro:IPR029437|interpro:IPR029438|mint:Q969F9|refseq:NP_001295187.1|refseq:NP_115759.2|panther:PTHR28633(orthology-group)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	-	-	figure legend:F2D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2021/07/28	2024/11/14	rogid:v6pL0ap1hoLI7VbA0j1M2ZEwlgw9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	intact-crc:7DFAB7AE84545887|rigid:9tD1w70K8WKDOc9m4Dz6U+JQsq4	false	green fluorescent protein tag:c-c	red fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9UPZ3	uniprotkb:A0A0H3NFP4	intact:EBI-10962552|uniprotkb:Q8N4U0|uniprotkb:D3DQY0|uniprotkb:O95942|uniprotkb:A8K8S1|uniprotkb:A8K6J8|uniprotkb:D3DQX9|ensembl:ENSP00000265967.5|ensembl:ENSP00000500370.1	intact:EBI-27055396	psi-mi:hps5_human(display_long)|uniprotkb:Hermansky-Pudlak syndrome 5 protein(gene name synonym)|uniprotkb:HPS5(gene name)|psi-mi:HPS5(display_short)|uniprotkb:AIBP63(gene name synonym)|uniprotkb:Alpha-integrin-binding protein 63(gene name synonym)|uniprotkb:KIAA1017(gene name synonym)|uniprotkb:Ruby-eye protein 2 homolog(gene name synonym)	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:""MI:0096""(pull down)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27056600|imex:IM-29147-13	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:231512""|ensembl:ENSG00000110756.18(gene)|ensembl:ENSG00000288445.2(gene)|ensembl:ENST00000349215.8(transcript)|ensembl:ENST00000671838.2(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0007596""(blood coagulation)|go:""GO:0031084""(BLOC-2 complex)|go:""GO:0046907""(intracellular transport)|go:""GO:0048066""(developmental pigmentation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:1903232""(melanosome assembly)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035431|interpro:IPR036322|mint:Q9UPZ3|refseq:NP_009147.3|refseq:NP_852608.1|refseq:NP_852609.1|refseq:XP_016872638.1|refseq:XP_016872639.1|refseq:XP_016872643.1|panther:PTHR23287(orthology-group)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	-	-	figure legend:F2D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2021/07/28	2024/11/14	rogid:L0sGn/+uTenUeRFEWs/pTbPGDrE9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	intact-crc:BEEE0ED6D58984AF|rigid:7x/cTXbusMX3hPJpmWYv+HxGJ4c	false	green fluorescent protein tag:c-c	red fluorescent protein tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q96AC1	uniprotkb:A0A0H3NFP4	intact:EBI-4399465|uniprotkb:Q14840|uniprotkb:Q86TY7|uniprotkb:B5TJY2|ensembl:ENSP00000340391.3|ensembl:ENSP00000378993.2|intact:EBI-21355423	intact:EBI-27055396	psi-mi:ferm2_human(display_long)|uniprotkb:FERMT2(gene name)|psi-mi:FERMT2(display_short)|uniprotkb:KIND2(gene name synonym)|uniprotkb:MIG2(gene name synonym)|uniprotkb:PLEKHC1(gene name synonym)|uniprotkb:Kindlin-2(gene name synonym)|uniprotkb:Mitogen-inducible gene 2 protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 1(gene name synonym)	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:""MI:0096""(pull down)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27056608|imex:IM-29147-33	intact-miscore:0.47	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001128471.1|refseq:NP_001128472.1|refseq:NP_006823.1|ensembl:ENSG00000073712.15(gene)|ensembl:ENST00000341590.8(transcript)|ensembl:ENST00000395631.6(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031674""(I band)|go:""GO:0033622""(integrin activation)|go:""GO:0033625""(positive regulation of integrin activation)|go:""GO:0034334""(adherens junction maintenance)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046332""(SMAD binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0051015""(actin filament binding)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060173""(limb development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902414""(protein localization to cell junction)|go:""GO:1902462""(positive regulation of mesenchymal stem cell proliferation)|go:""GO:1903691""(positive regulation of wound healing, spreading of epidermal cells)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR037837|interpro:IPR037843|interpro:IPR040790|mint:Q96AC1|rcsb pdb:2LGX|rcsb pdb:2LKO|rcsb pdb:2MSU|rcsb pdb:4F7H|rcsb pdb:6U4N|rcsb pdb:6XTJ|reactome:R-HSA-446353|reactome:R-HSA-9013149|reactome:R-HSA-9013423|panther:PTHR16160(orthology-group)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	-	-	figure legend:F2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2021/07/28	2024/11/14	rogid:nmlzKrHEw/aEw6C8i9+G/80jbuE9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	intact-crc:516E06CEF36EE1B4|rigid:4L/qXdDvl89BImO2gpu4gDscs7o	false	ha tag:?-?	green fluorescent protein tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q03135	uniprotkb:A0A0H3NFP4	intact:EBI-603614|uniprotkb:Q9UGP1|uniprotkb:Q9UNG1|uniprotkb:Q9UQH6|ensembl:ENSP00000339191.2	intact:EBI-27055396	psi-mi:cav1_human(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:""MI:0096""(pull down)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27056626|imex:IM-29147-15	intact-miscore:0.47	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105974.13(gene)|ensembl:ENST00000341049.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001525""(angiogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0001960""(negative regulation of cytokine-mediated signaling pathway)|go:""GO:0002067""(glandular epithelial cell differentiation)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0002095""(caveolar macromolecular signaling complex)|go:""GO:0002931""(response to ischemia)|go:""GO:0003057""(regulation of the force of heart contraction by chemical signal)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005113""(patched binding)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0005938""(cell cortex)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006940""(regulation of smooth muscle contraction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007595""(lactation)|go:""GO:0008104""(protein localization)|go:""GO:0008142""(oxysterol binding)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009617""(response to bacterium)|go:""GO:0010524""(positive regulation of calcium ion transport into cytosol)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0015031""(protein transport)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0016050""(vesicle organization)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0019065""(receptor-mediated endocytosis of virus by host cell)|go:""GO:0019217""(regulation of fatty acid metabolic process)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019915""(lipid storage)|go:""GO:0030154""(cell differentiation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030857""(negative regulation of epithelial cell differentiation)|go:""GO:0030879""(mammary gland development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032507""(maintenance of protein location in cell)|go:""GO:0032570""(response to progesterone)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033484""(intracellular nitric oxide homeostasis)|go:""GO:0034141""(positive regulation of toll-like receptor 3 signaling pathway)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038166""(angiotensin-activated signaling pathway)|go:""GO:0042310""(vasoconstriction)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043627""(response to estrogen)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044860""(protein localization to plasma membrane raft)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045019""(negative regulation of nitric oxide biosynthetic process)|go:""GO:0045121""(membrane raft)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048550""(negative regulation of pinocytosis)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051899""(membrane depolarization)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060355""(positive regulation of cell adhesion molecule production)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070320""(inward rectifier potassium channel inhibitor activity)|go:""GO:0070836""(caveola assembly)|go:""GO:0071218""(cellular response to misfolded protein)|go:""GO:0071360""(cellular response to exogenous dsRNA)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0071455""(cellular response to hyperoxia)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0098903""(regulation of membrane repolarization during action potential)|go:""GO:0098909""(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900027""(regulation of ruffle assembly)|go:""GO:1901380""(negative regulation of potassium ion transmembrane transport)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1903598""(positive regulation of gap junction assembly)|go:""GO:1903609""(negative regulation of inward rectifier potassium channel activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000535""(regulation of entry of bacterium into host cell)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR018361|mint:Q03135|rcsb pdb:7SC0|reactome:R-HSA-163560|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-210991|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9617828|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001744.2|dip:DIP-5960N|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:275777""|efo:""Orphanet:528""|panther:PTHR10844(orthology-group)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	-	-	figure legend:F2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2021/07/28	2025/02/28	rogid:+JhGp5YmhT3JLeTgHHBTHu9r34c9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	intact-crc:95990ABCD672BD81|rigid:Lo3mreZaUqIgQZgkd09QFib9WmU	false	ha tag:?-?	green fluorescent protein tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q92609	uniprotkb:A0A0H3NFP4	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|uniprotkb:C9JP52|ensembl:ENSP00000253692.6|ensembl:ENSP00000398127.4	intact:EBI-27055396	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:""MI:0096""(pull down)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27056634|imex:IM-29147-35	intact-miscore:0.47	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1|ensembl:ENSG00000131374.15(gene)|ensembl:ENST00000253692.11(transcript)|ensembl:ENST00000429383.8(transcript)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005776""(autophagosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0035612""(AP-2 adaptor complex binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042594""(response to starvation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:1905394""(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|panther:PTHR22957(orthology-group)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	-	-	figure legend:F2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2021/07/28	2024/11/14	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	intact-crc:422A9C70D349AFF7|rigid:KxhKRLE0Ep7jilCFdqrL8HjY4kM	false	ha tag:?-?	green fluorescent protein tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q14254	uniprotkb:A0A0H3NFP4	intact:EBI-348613|ensembl:ENSP00000378368.3	intact:EBI-27055396	psi-mi:flot2_human(display_long)|uniprotkb:FLOT2(gene name)|psi-mi:FLOT2(display_short)|uniprotkb:ESA1(gene name synonym)|uniprotkb:M17S1(gene name synonym)|uniprotkb:Epidermal surface antigen(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 1(gene name synonym)	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:""MI:0096""(pull down)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27056642|imex:IM-29147-37	intact-miscore:0.47	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004466.2|ensembl:ENSG00000132589.16(gene)|ensembl:ENST00000394908.9(transcript)|go:""GO:0001931""(uropod)|go:""GO:0002020""(protease binding)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0008544""(epidermis development)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016600""(flotillin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031982""(vesicle)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0044860""(protein localization to plasma membrane raft)|go:""GO:0045661""(regulation of myoblast differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098937""(anterograde dendritic transport)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1902992""(negative regulation of amyloid precursor protein catabolic process)|go:""GO:1903905""(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:Q14254|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9696264|reactome:R-HSA-9696273|refseq:XP_016879883.1|refseq:XP_016879884.1|panther:PTHR13806(orthology-group)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	-	-	figure legend:F2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2021/07/28	2024/11/14	rogid:P9htlLzTYk+eDKKesqCEPe/1BJA9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	intact-crc:E85A2C8E7C2120E7|rigid:E8jCTtKjaEsjzUiBms+ZZHtS0vg	false	ha tag:?-?	green fluorescent protein tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9P0K7	uniprotkb:A0A0H3NFP4	intact:EBI-1023749|uniprotkb:Q6V1W9|uniprotkb:Q7Z5I4|uniprotkb:Q7Z733|uniprotkb:Q9P2L2|uniprotkb:Q9Y3T5|uniprotkb:E9PED3|intact:EBI-2555698|ensembl:ENSP00000265109.3|ensembl:ENSP00000388725.2|ensembl:ENSP00000422942.1	intact:EBI-27055396	psi-mi:rai14_human(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:RAI14(gene name)|psi-mi:RAI14(display_short)|uniprotkb:KIAA1334(gene name synonym)|uniprotkb:NORPEG(gene name synonym)	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:""MI:0096""(pull down)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27056650|imex:IM-29147-17	intact-miscore:0.47	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138992.1|refseq:NP_001138993.1|refseq:NP_001138994.1|refseq:NP_001138995.1|refseq:NP_001138997.1|refseq:NP_056392.2|refseq:XP_011512319.1|refseq:XP_011512320.1|refseq:XP_011512321.1|refseq:XP_011512322.1|refseq:XP_011512323.1|refseq:XP_011512324.1|refseq:XP_006714532.1|refseq:XP_016864824.1|ensembl:ENSG00000039560.14(gene)|ensembl:ENST00000265109.8(transcript)|ensembl:ENST00000428746.6(transcript)|ensembl:ENST00000503673.5(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030154""(cell differentiation)|go:""GO:0070161""(anchoring junction)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR042420|mint:Q9P0K7|panther:PTHR24129(orthology-group)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	-	-	figure legend:F2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2021/07/28	2024/11/14	rogid:m5hQYx6HEi9QEAey1UiNpeAp6tw9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	intact-crc:8A15238DE7F5E5F5|rigid:AN7QvwR5hWw9gy1rP9A72L/pgmw	false	ha tag:?-?	green fluorescent protein tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9UPZ3	uniprotkb:A0A0H3NFP4	intact:EBI-10962552|uniprotkb:Q8N4U0|uniprotkb:D3DQY0|uniprotkb:O95942|uniprotkb:A8K8S1|uniprotkb:A8K6J8|uniprotkb:D3DQX9|ensembl:ENSP00000265967.5|ensembl:ENSP00000500370.1	intact:EBI-27055396	psi-mi:hps5_human(display_long)|uniprotkb:Hermansky-Pudlak syndrome 5 protein(gene name synonym)|uniprotkb:HPS5(gene name)|psi-mi:HPS5(display_short)|uniprotkb:AIBP63(gene name synonym)|uniprotkb:Alpha-integrin-binding protein 63(gene name synonym)|uniprotkb:KIAA1017(gene name synonym)|uniprotkb:Ruby-eye protein 2 homolog(gene name synonym)	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27056670|imex:IM-29147-19	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:231512""|ensembl:ENSG00000110756.18(gene)|ensembl:ENSG00000288445.2(gene)|ensembl:ENST00000349215.8(transcript)|ensembl:ENST00000671838.2(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0007596""(blood coagulation)|go:""GO:0031084""(BLOC-2 complex)|go:""GO:0046907""(intracellular transport)|go:""GO:0048066""(developmental pigmentation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:1903232""(melanosome assembly)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035431|interpro:IPR036322|mint:Q9UPZ3|refseq:NP_009147.3|refseq:NP_852608.1|refseq:NP_852609.1|refseq:XP_016872638.1|refseq:XP_016872639.1|refseq:XP_016872643.1|panther:PTHR23287(orthology-group)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	-	-	-	figure legend:F5E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela-T-Rex)|taxid:9606(Homo sapiens HeLa-T-Rex epitheloid cervical carcinoma cell)	-	2021/07/28	2024/11/14	rogid:L0sGn/+uTenUeRFEWs/pTbPGDrE9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	intact-crc:D442DE6155CB57E8|rigid:7x/cTXbusMX3hPJpmWYv+HxGJ4c	false	flag tag:?-?	ha tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0H3NFP4	uniprotkb:P35580	intact:EBI-27055396	intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45|ensembl:ENSP00000269243.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|interpro:IPR002928(Myosin tail)|ensembl:ENSG00000133026.14(gene)|ensembl:ENST00000269243.8(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0016459""(myosin complex)|go:""GO:0016460""(myosin II complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030048""(actin filament-based movement)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|go:""GO:0030496""(midbody)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032982""(myosin filament)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0042641""(actomyosin)|go:""GO:0043531""(ADP binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097513""(myosin II filament)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N|panther:PTHR45615(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P60660	intact:EBI-27055396	intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9|ensembl:ENSP00000446955.2|ensembl:ENSP00000448101.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_066299.2|refseq:NP_524147.2|ensembl:ENSG00000092841.19(gene)|ensembl:ENST00000548293.5(transcript)|ensembl:ENST00000550697.6(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0006936""(muscle contraction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0016020""(membrane)|go:""GO:0016459""(myosin complex)|go:""GO:0016460""(myosin II complex)|go:""GO:0016461""(unconventional myosin complex)|go:""GO:0030049""(muscle filament sliding)|go:""GO:0031982""(vesicle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR050230|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|panther:PTHR23048(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O14950	intact:EBI-27055396	intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500.5|ensembl:ENSP00000383037.5|ensembl:ENSP00000463559.1|ensembl:ENSP00000464464.1|ensembl:ENSP00000496809.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680.14(gene)|ensembl:ENST00000237500.10(transcript)|ensembl:ENST00000400175.9(transcript)|ensembl:ENST00000581193.5(transcript)|ensembl:ENST00000584539.1(transcript)|ensembl:ENST00000648965.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016460""(myosin II complex)|go:""GO:0030016""(myofibril)|go:""GO:0030018""(Z disc)|go:""GO:0032036""(myosin heavy chain binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|interpro:IPR050403|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|panther:PTHR23049(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P55884	intact:EBI-27055396	intact:EBI-366696|uniprotkb:Q2NL77|uniprotkb:Q9UMF9|uniprotkb:A4D208|intact:EBI-25643250|ensembl:ENSP00000354125.4|ensembl:ENSP00000380206.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:eif3b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:Prt1 homolog(gene name synonym)|uniprotkb:EIF3B(gene name)|psi-mi:EIF3B(display_short)|uniprotkb:EIF3S9(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR14068(orthology-group)|refseq:NP_001032360.1|refseq:NP_003742.2|ensembl:ENSG00000106263.19(gene)|ensembl:ENST00000360876.9(transcript)|ensembl:ENST00000397011.2(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0045202""(synapse)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071541""(eukaryotic translation initiation factor 3 complex, eIF3m)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0075525""(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:P55884|rcsb pdb:2KRB|rcsb pdb:2NLW|rcsb pdb:5K1H|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8XXN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_011513901.1|refseq:XP_011513902.1|refseq:XP_016868241.1|dip:DIP-31113N"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:MxQFPvmuOcO/S+4NqzToozWr8K89606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P98175	intact:EBI-27055396	intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|ensembl:ENSP00000366829.3|uniprotkb:A0A0A0MR66	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:2886""|ensembl:ENSG00000182872.16(gene)|ensembl:ENST00000377604.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048025""(negative regulation of mRNA splicing, via spliceosome)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1905288""(vascular associated smooth muscle cell apoptotic process)|go:""GO:1905461""(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:""GO:1990874""(vascular associated smooth muscle cell proliferation)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_001191397.1|refseq:NP_005667.2|refseq:NP_690595.1|panther:PTHR13948(orthology-group)|ensembl:ENST00000329236.8|ensembl:ENSP00000328848.8|ensembl:ENST00000345781.10|ensembl:ENSP00000329659.6|ensembl:ENSP00000366829.3|ensembl:ENST00000628161.2|ensembl:ENSP00000486115.1"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8TCT9	intact:EBI-27055396	intact:EBI-347472|uniprotkb:Q540H8|uniprotkb:Q5JWP2|uniprotkb:Q5JWP3|uniprotkb:Q5JWP4|uniprotkb:Q5JWP5|uniprotkb:Q7Z4F2|uniprotkb:Q86Y35|uniprotkb:Q95H87|uniprotkb:Q9H110|uniprotkb:Q9H111|uniprotkb:Q15K36|uniprotkb:B2RAY5|uniprotkb:E1P5L3|ensembl:ENSP00000343032.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:hm13_human(display_long)|uniprotkb:HM13(gene name)|psi-mi:HM13(display_short)|uniprotkb:H13(gene name synonym)|uniprotkb:PSL3(gene name synonym)|uniprotkb:SPP(gene name synonym)|uniprotkb:Signal peptide peptidase(gene name synonym)|uniprotkb:Presenilin-like protein 3(gene name synonym)|uniprotkb:Intramembrane protease 1(gene name synonym)|uniprotkb:IMP1(gene name synonym)|uniprotkb:MSTP086(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_110416.1|refseq:NP_848695.1|refseq:NP_848696.1|refseq:NP_848697.1|panther:PTHR12174(orthology-group)|ensembl:ENSG00000101294.20(gene)|ensembl:ENST00000340852.9(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006465""(signal peptide processing)|go:""GO:0008233""(peptidase activity)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0033619""(membrane protein proteolysis)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0036513""(Derlin-1 retrotranslocation complex)|go:""GO:0042500""(aspartic endopeptidase activity, intramembrane cleaving)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:1904211""(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR007369(Peptidase A22B, signal peptide peptidase)|mint:Q8TCT9|reactome:R-HSA-9707587"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:DxNjJDcc+zomfXAj0TEaByKeNqc9606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q14152	intact:EBI-27055396	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|uniprotkb:B4DYS1|uniprotkb:F5H335|ensembl:ENSP00000358140.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR14005(orthology-group)|refseq:NP_003741.1|ensembl:ENSG00000107581.14(gene)|ensembl:ENST00000369144.8(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0002188""(translation reinitiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0043614""(multi-eIF complex)|go:""GO:0071540""(eukaryotic translation initiation factor 3 complex, eIF3e)|go:""GO:0071541""(eukaryotic translation initiation factor 3 complex, eIF3m)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0075525""(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|interpro:IPR054711|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8RG0|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O14735	intact:EBI-27055396	intact:EBI-358858|uniprotkb:Q6FGU1|uniprotkb:Q6ZN70|ensembl:ENSP00000219789.6|ensembl:ENSP00000454453.1|ensembl:ENSP00000457339.1|uniprotkb:B4DUV0|uniprotkb:H3BTV1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:cdipt_human(display_long)|uniprotkb:CDIPT(gene name)|psi-mi:CDIPT(display_short)|uniprotkb:PIS(gene name synonym)|uniprotkb:PIS1(gene name synonym)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001273514.1|refseq:NP_006310.1|ensembl:ENSG00000103502.14(gene)|ensembl:ENST00000219789.11(transcript)|ensembl:ENST00000569956.5(transcript)|ensembl:ENST00000570016.5(transcript)|go:""GO:0003881""(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|interpro:IPR048254|mint:O14735|reactome:R-HSA-1483226|dip:DIP-54492N|panther:PTHR15362(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:SIs1nKd3UxZREA2Sxl4MxxBNYvM9606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q6IS14	intact:EBI-27055396	intact:EBI-6151859|ensembl:ENSP00000430706.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:if5al_human(display_long)|uniprotkb:Eukaryotic initiation factor 5A isoform 1-like(gene name synonym)|uniprotkb:EIF5AL1(gene name)|psi-mi:EIF5AL1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001093162.1|ensembl:ENSG00000253626.4(gene)|ensembl:ENST00000520547.4(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006414""(translational elongation)|go:""GO:0043022""(ribosome binding)|go:""GO:0045901""(positive regulation of translational elongation)|go:""GO:0045905""(positive regulation of translational termination)|interpro:IPR001884(""Eukaryotic initiation factor 5A hypusine (eIF-5A)"")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|interpro:IPR048670|mint:Q6IS14|panther:PTHR11673(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:sV7lnYqekOx0EisZGSpo8EWAl+09606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O14617	intact:EBI-27055396	intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:664511""|dip:DIP-46793N|ensembl:ENSG00000065000.20(gene)|ensembl:ENST00000345016.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016182""(synaptic vesicle budding from endosome)|go:""GO:0016183""(synaptic vesicle coating)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0032438""(melanosome organization)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0043195""(terminal bouton)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046907""(intracellular transport)|go:""GO:0048007""(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0048499""(synaptic vesicle membrane organization)|go:""GO:0051138""(positive regulation of NK T cell differentiation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140916""(zinc ion import into lysosome)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|refseq:NP_001248755.1|refseq:NP_003929.4|efo:""Orphanet:1000""|efo:""Orphanet:54""|panther:PTHR22781(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9P0J0	intact:EBI-27055396	intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|ensembl:ENSP00000423673.1|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000186010.19(gene)|ensembl:ENST00000507754.9(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0009060""(aerobic respiration)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032981""(mitochondrial respiratory chain complex I assembly)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045039""(protein insertion into mitochondrial inner membrane)|go:""GO:0045271""(respiratory chain complex I)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098803""(respiratory chain complex)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9837999|refseq:NP_057049.5|efo:""Orphanet:146""|dip:DIP-31180N|panther:PTHR12966(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9BXS4	intact:EBI-27055396	intact:EBI-7054441|uniprotkb:Q4VBP9|uniprotkb:O75393|intact:MINT-8201752|uniprotkb:Q96KX7|uniprotkb:Q5T705|uniprotkb:B3KQL7|ensembl:ENSP00000234831.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:tmm59_human(display_long)|uniprotkb:TMEM59(gene name)|psi-mi:TMEM59(display_short)|uniprotkb:C1orf8(gene name synonym)|uniprotkb:Liver membrane-bound protein(gene name synonym)|uniprotkb:HSPC001(orf name)|uniprotkb:UNQ169/PRO195(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001291972.1|refseq:NP_001291978.1|refseq:NP_001291979.1|refseq:NP_001291980.1|refseq:NP_001291981.1|refseq:NP_001291995.1|refseq:NP_004863.2|ensembl:ENSG00000116209.12(gene)|ensembl:ENST00000234831.10(transcript)|go:""GO:0000137""(Golgi cis cisterna)|go:""GO:0000138""(Golgi trans cisterna)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0005886""(plasma membrane)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006914""(autophagy)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0031902""(late endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|interpro:IPR022065|mint:Q9BXS4|reactome:R-HSA-9013407|reactome:R-HSA-9696273|panther:PTHR28652(orthology-group)"	-	-	comment:mint	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:yA2dq3FVXnxw9Peh6f3UBqGzFpM9606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P30049	intact:EBI-27055396	intact:EBI-1049505|uniprotkb:Q6FG90|uniprotkb:D6W5Y3|ensembl:ENSP00000215375.1|ensembl:ENSP00000378995.1|ensembl:ENSP00000464863.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:atpd_human(display_long)|uniprotkb:ATP5F1D(gene name)|psi-mi:ATP5F1D(display_short)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:ATP5D(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055452|imex:IM-29147-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000099624.8(gene)|ensembl:ENST00000215375.7(transcript)|ensembl:ENST00000395633.5(transcript)|ensembl:ENST00000591660.5(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0009060""(aerobic respiration)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0033615""(mitochondrial proton-transporting ATP synthase complex assembly)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046688""(response to copper ion)|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|interpro:IPR036794|interpro:IPR048937|mint:P30049|rcsb pdb:8H9F|rcsb pdb:8H9J|rcsb pdb:8H9M|rcsb pdb:8H9Q|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|refseq:NP_001001975.1|refseq:NP_001678.1|efo:""Orphanet:254913""|panther:PTHR13822(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:OA8if7wpjwV6hkkaLqPyz6YDljc9606	intact-crc:475842C32714F1CB|rigid:XHql29f+IJuBkGAzhZQX1lVY2/o	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P98175	intact:EBI-10726177	intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|ensembl:ENSP00000366829.3|uniprotkb:A0A0A0MR66	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055516|imex:IM-29147-3	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:2886""|ensembl:ENSG00000182872.16(gene)|ensembl:ENST00000377604.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048025""(negative regulation of mRNA splicing, via spliceosome)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1905288""(vascular associated smooth muscle cell apoptotic process)|go:""GO:1905461""(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:""GO:1990874""(vascular associated smooth muscle cell proliferation)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_001191397.1|refseq:NP_005667.2|refseq:NP_690595.1|panther:PTHR13948(orthology-group)|ensembl:ENST00000329236.8|ensembl:ENSP00000328848.8|ensembl:ENST00000345781.10|ensembl:ENSP00000329659.6|ensembl:ENSP00000366829.3|ensembl:ENST00000628161.2|ensembl:ENSP00000486115.1"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2024/11/14	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606	intact-crc:8346E736E53814DE|rigid:5DBwk7Hy1RqpEfO6zClPsuo5C0c	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9Y2W1	intact:EBI-10726177	intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634.5|ensembl:ENSP00000433825.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055516|imex:IM-29147-3	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_005110.2|refseq:NP_001308400.1|refseq:NP_001308402.1|ensembl:ENSG00000054118.15(gene)|ensembl:ENST00000354618.10(transcript)|ensembl:ENST00000469141.6(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016592""(mediator complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0042753""(positive regulation of circadian rhythm)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|panther:PTHR15268(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2024/11/14	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606	intact-crc:8346E736E53814DE|rigid:5DBwk7Hy1RqpEfO6zClPsuo5C0c	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9NWB6	intact:EBI-10726177	intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055516|imex:IM-29147-3	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_060481.3|ensembl:ENSG00000134884.15(gene)|ensembl:ENST00000400198.8(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0045296""(cadherin binding)|interpro:IPR033371|mint:Q9NWB6|panther:PTHR31711(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2024/11/14	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606	intact-crc:8346E736E53814DE|rigid:5DBwk7Hy1RqpEfO6zClPsuo5C0c	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O14980	intact:EBI-27055528	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863.2|ensembl:ENSP00000385559.1|ensembl:ENSP00000385942.2|ensembl:ENSP00000503167.1|ensembl:ENSP00000503419.1|ensembl:ENSP00000503482.1|ensembl:ENSP00000503572.1|ensembl:ENSP00000503809.1|ensembl:ENSP00000504087.1|ensembl:ENSP00000504198.1|ensembl:ENSP00000504247.1|ensembl:ENSP00000504543.1|ensembl:ENSP00000504594.1|ensembl:ENSP00000504848.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:98838""|ensembl:ENSG00000082898.19(gene)|ensembl:ENST00000401558.7(transcript)|ensembl:ENST00000404992.6(transcript)|ensembl:ENST00000406957.5(transcript)|ensembl:ENST00000676553.1(transcript)|ensembl:ENST00000676667.1(transcript)|ensembl:ENST00000677150.1(transcript)|ensembl:ENST00000677239.1(transcript)|ensembl:ENST00000677417.1(transcript)|ensembl:ENST00000677813.1(transcript)|ensembl:ENST00000677814.1(transcript)|ensembl:ENST00000677928.1(transcript)|ensembl:ENST00000677933.1(transcript)|ensembl:ENST00000678182.1(transcript)|ensembl:ENST00000678790.1(transcript)|go:""GO:0000054""(ribosomal subunit export from nucleus)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0000776""(kinetochore)|go:""GO:0003723""(RNA binding)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005642""(annulate lamellae)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015030""(Cajal body)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032434""(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|interpro:IPR045065|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|rcsb pdb:7B51|rcsb pdb:9B62|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|reactome:R-HSA-9768919|reactome:R-HSA-9828806|reactome:R-HSA-9856649|refseq:NP_003391.1|refseq:XP_006712157.1|refseq:XP_011531399.1|dip:DIP-33678N|panther:PTHR11223(orthology-group)|ensembl:ENSP00000384863.2|ensembl:ENSP00000385942.2|ensembl:ENSP00000385559.1|ensembl:ENSP00000504247.1|ensembl:ENSP00000503809.1|ensembl:ENSP00000503167.1|ensembl:ENSP00000504087.1|ensembl:ENSP00000503572.1|ensembl:ENSP00000504543.1|ensembl:ENSP00000504848.1|ensembl:ENSP00000504198.1|ensembl:ENSP00000503482.1|ensembl:ENSP00000504594.1|ensembl:ENSP00000503419.1"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q92616	intact:EBI-27055528	intact:EBI-356221|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692|ensembl:ENSP00000300648.6	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_006827.1|ensembl:ENSG00000089154.11(gene)|ensembl:ENST00000300648.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0006417""(regulation of translation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016020""(membrane)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0055106""(ubiquitin-protein transferase regulator activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0140469""(GCN2-mediated signaling)|go:""GO:0160127""(protein-RNA covalent cross-linking repair)|go:""GO:0170011""(stalled ribosome sensor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|panther:PTHR23346(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:aXrR83M54Nh1pnmdgL71NurSSfI9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O14654	intact:EBI-27055528	intact:EBI-356594|ensembl:ENSP00000505547.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_003595.1|ensembl:ENSG00000133124.12(gene)|ensembl:ENST00000564206.2(transcript)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|mint:O14654|reactome:R-HSA-2428928|panther:PTHR10614(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P35580	intact:EBI-27055528	intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45|ensembl:ENSP00000269243.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|interpro:IPR002928(Myosin tail)|ensembl:ENSG00000133026.14(gene)|ensembl:ENST00000269243.8(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0016459""(myosin complex)|go:""GO:0016460""(myosin II complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030048""(actin filament-based movement)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|go:""GO:0030496""(midbody)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032982""(myosin filament)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0042641""(actomyosin)|go:""GO:0043531""(ADP binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097513""(myosin II filament)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N|panther:PTHR45615(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9NVI1	intact:EBI-27055528	intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842.8|ensembl:ENSP00000512832.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000140525.20(gene)|ensembl:ENST00000310775.12(transcript)|ensembl:ENST00000696719.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0036297""(interstrand cross-link repair)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:1990391""(DNA repair complex)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|rcsb pdb:7ZF1|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-6783310|reactome:R-HSA-6796648|refseq:NP_001106849.1|refseq:NP_060663.2|refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|efo:""Orphanet:84""|dip:DIP-29381N|panther:PTHR21818(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9HAV4	intact:EBI-27055528	intact:EBI-517949|uniprotkb:Q5JTE6|uniprotkb:Q96G48|uniprotkb:Q96HN3|uniprotkb:Q9BWM6|uniprotkb:Q9BZV5|uniprotkb:Q9H9M4|uniprotkb:Q9NT89|uniprotkb:Q9NW39|uniprotkb:Q9ULC9|ensembl:ENSP00000265351.7	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:xpo5_human(display_long)|uniprotkb:Ran-binding protein 21(gene name synonym)|uniprotkb:XPO5(gene name)|psi-mi:XPO5(display_short)|uniprotkb:KIAA1291(gene name synonym)|uniprotkb:RANBP21(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_065801.1|ensembl:ENSG00000124571.18(gene)|ensembl:ENST00000265351.12(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0010586""(miRNA metabolic process)|go:""GO:0016442""(RISC complex)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035281""(pre-miRNA export from nucleus)|go:""GO:0042565""(RNA nuclear export complex)|go:""GO:0070883""(pre-miRNA binding)|go:""GO:1905172""(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR045065|interpro:IPR045478|mint:Q9HAV4|rcsb pdb:3A6P|rcsb pdb:5YU6|rcsb pdb:5YU7|reactome:R-HSA-203927|dip:DIP-34547N|panther:PTHR11223(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:wuUAxvyCl/u7CRtQLMK9McSoUrM9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P20020	intact:EBI-27055528	intact:EBI-5279998|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|ensembl:ENSP00000392043.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000070961.17(gene)|efo:""Orphanet:528084""|ensembl:ENST00000428670.8(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0003056""(regulation of vascular associated smooth muscle contraction)|go:""GO:0005388""(P-type calcium transporter activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0015085""(calcium ion transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030501""(positive regulation of bone mineralization)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042995""(cell projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051481""(negative regulation of cytosolic calcium ion concentration)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098684""(photoreceptor ribbon synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1990034""(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P20020|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9662360|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_011536709.1|refseq:XP_016874847.1|panther:PTHR24093(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q13451	intact:EBI-27055528	intact:EBI-306914|ensembl:ENSP00000349811.3|ensembl:ENSP00000441205.1|ensembl:ENSP00000444810.1|uniprotkb:Q5TGM6|uniprotkb:F5H7R1|uniprotkb:Q59EB8	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:fkbp5_human(display_long)|uniprotkb:FKBP5(gene name)|psi-mi:FKBP5(display_short)|uniprotkb:AIG6(gene name synonym)|uniprotkb:FKBP51(gene name synonym)|uniprotkb:FK506-binding protein 5(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:54 kDa progesterone receptor-associated immunophilin(gene name synonym)|uniprotkb:FKBP54(gene name synonym)|uniprotkb:FF1 antigen(gene name synonym)|uniprotkb:HSP90-binding immunophilin(gene name synonym)|uniprotkb:Androgen-regulated protein 6(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001139247.1|refseq:NP_001139248.1|refseq:NP_004108.1|ensembl:ENSG00000096060.15(gene)|ensembl:ENST00000357266.9(transcript)|ensembl:ENST00000536438.5(transcript)|ensembl:ENST00000539068.5(transcript)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005528""(FK506 binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0009617""(response to bacterium)|go:""GO:0016020""(membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042220""(response to cocaine)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097305""(response to alcohol)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR046357|interpro:IPR050754|mint:Q13451|rcsb pdb:1KT0|rcsb pdb:3O5P|rcsb pdb:3O5D|rcsb pdb:3O5E|rcsb pdb:3O5F|rcsb pdb:3O5G|rcsb pdb:3O5I|rcsb pdb:3O5J|rcsb pdb:3O5K|rcsb pdb:3O5L|rcsb pdb:3O5M|rcsb pdb:3O5O|rcsb pdb:3O5Q|rcsb pdb:3O5R|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRK|rcsb pdb:4DRM|rcsb pdb:4DRN|rcsb pdb:4DRO|rcsb pdb:4DRP|rcsb pdb:4DRQ|rcsb pdb:4JFI|rcsb pdb:4JFJ|rcsb pdb:4JFK|rcsb pdb:4JFL|rcsb pdb:4JFM|rcsb pdb:4R0X|rcsb pdb:4TW6|rcsb pdb:4TW7|rcsb pdb:4TX0|rcsb pdb:4W9O|rcsb pdb:4W9P|rcsb pdb:4W9Q|rcsb pdb:5BXJ|rcsb pdb:5DIT|rcsb pdb:5DIU|rcsb pdb:5DIV|rcsb pdb:5NJX|rcsb pdb:5OBK|rcsb pdb:5OMP|rcsb pdb:6SAF|rcsb pdb:6TX4|rcsb pdb:6TX5|rcsb pdb:6TX6|rcsb pdb:6TX7|rcsb pdb:6TX8|rcsb pdb:6TX9|rcsb pdb:6TXX|rcsb pdb:7A6W|rcsb pdb:7A6X|rcsb pdb:7AOT|rcsb pdb:7AOU|rcsb pdb:7APQ|rcsb pdb:7APS|rcsb pdb:7APT|rcsb pdb:7APW|rcsb pdb:7AWF|rcsb pdb:7AWX|rcsb pdb:7B9Y|rcsb pdb:7B9Z|rcsb pdb:7BA0|rcsb pdb:7ETT|rcsb pdb:7ETU|rcsb pdb:7ETV|rcsb pdb:7L7I|rcsb pdb:7R0L|rcsb pdb:8BA6|rcsb pdb:8BAJ|rcsb pdb:8CCA|rcsb pdb:8CCB|rcsb pdb:8CCC|rcsb pdb:8CCD|rcsb pdb:8CCE|rcsb pdb:8CCF|rcsb pdb:8CCG|rcsb pdb:8CCH|rcsb pdb:8CHN|rcsb pdb:8CHP|rcsb pdb:8CHQ|rcsb pdb:8CHR|rcsb pdb:8FFW|rcsb pdb:8PC2|rcsb pdb:8PJ8|rcsb pdb:8PJA|rcsb pdb:8R5K|rcsb pdb:9EU6|rcsb pdb:9EU7|rcsb pdb:9EU8|rcsb pdb:9EU9|rcsb pdb:9EUA|rcsb pdb:9EUB|rcsb pdb:9EUC|rcsb pdb:9EUD|rcsb pdb:9EUE|rcsb pdb:9EY3|rcsb pdb:9EY4|reactome:R-HSA-3371497|reactome:R-HSA-8939211|reactome:R-HSA-9022699|refseq:NP_001139249.1|dip:DIP-27597N|panther:PTHR10516(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:m2Bnn01E13sovh3BwG71Pgqjdx89606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y2Z0	intact:EBI-27055528	intact:EBI-307008|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6|ensembl:ENSP00000367208.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001124384.1|refseq:NP_006695.1|ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000343788.10(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007051""(spindle organization)|go:""GO:0014841""(skeletal muscle satellite cell proliferation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032991""(protein-containing complex)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0106222""(lncRNA binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|reactome:R-HSA-9660826|refseq:NP_001307760.1|dip:DIP-53799N|panther:PTHR45862(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q15021	intact:EBI-27055528	intact:EBI-1044041|uniprotkb:Q8N6U3|uniprotkb:D3DUR4|ensembl:ENSP00000325017.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:cnd1_human(display_long)|uniprotkb:NCAPD2(gene name)|psi-mi:NCAPD2(display_short)|uniprotkb:CAPD2(gene name synonym)|uniprotkb:KIAA0159(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit D2(gene name synonym)|uniprotkb:Chromosome condensation-related SMC-associated protein 1(gene name synonym)|uniprotkb:Chromosome-associated protein D2(gene name synonym)|uniprotkb:XCAP-D2 homolog(gene name synonym)|uniprotkb:CNAP1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_055680.3|ensembl:ENSG00000010292.13(gene)|ensembl:ENST00000315579.10(transcript)|go:""GO:0000779""(condensed chromosome, centromeric region)|go:""GO:0000793""(condensed chromosome)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000796""(condensin complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007076""(mitotic chromosome condensation)|go:""GO:0010032""(meiotic chromosome condensation)|go:""GO:0016020""(membrane)|go:""GO:0042393""(histone binding)|go:""GO:0051301""(cell division)|go:""GO:0051984""(positive regulation of chromosome segregation)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:1905821""(positive regulation of chromosome condensation)|interpro:IPR007673(Non-SMC condensin subunit, XCAP-D2/Cnd1)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024324|interpro:IPR026971|interpro:IPR032682|mint:Q15021|reactome:R-HSA-2514853|panther:PTHR14222(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:lFz1E3CjOD76OsuGtokfR7Ujvnw9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P35579	intact:EBI-27055528	intact:EBI-350338|uniprotkb:O60805|uniprotkb:Q86T83|intact:EBI-1054343|intact:EBI-25631636|uniprotkb:A8K6E4|uniprotkb:Q60FE2|ensembl:ENSP00000216181.6	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:182050""|efo:""Orphanet:477742""|efo:""Orphanet:90635""|ensembl:ENSG00000100345.23(gene)|ensembl:ENST00000216181.11(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000212""(meiotic spindle organization)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0001931""(uropod)|go:""GO:0003723""(RNA binding)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005826""(actomyosin contractile ring)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016604""(nuclear body)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030220""(platelet formation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032418""(lysosome localization)|go:""GO:0032506""(cytokinetic process)|go:""GO:0032796""(uropod organization)|go:""GO:0032982""(myosin filament)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042641""(actomyosin)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043531""(ADP binding)|go:""GO:0043534""(blood vessel endothelial cell migration)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051015""(actin filament binding)|go:""GO:0051295""(establishment of meiotic spindle localization)|go:""GO:0060471""(cortical granule exocytosis)|go:""GO:0060473""(cortical granule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097513""(myosin II filament)|go:""GO:1903919""(negative regulation of actin filament severing)|go:""GO:1903923""(positive regulation of protein processing in phagocytic vesicle)|go:""GO:1905684""(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|reactome:R-HSA-9725370|refseq:NP_002464.1|refseq:XP_011528499.1|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|panther:PTHR45615(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q14160	intact:EBI-27055528	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000349486.2|ensembl:ENSP00000484041.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_056171.3|refseq:NP_874365.3|ensembl:ENSG00000180900.20(gene)|ensembl:ENSG00000274287.4(gene)|ensembl:ENST00000356994.7(transcript)|ensembl:ENST00000612204.4(transcript)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001843""(neural tube closure)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016080""(synaptic vesicle targeting)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0034750""(Scrib-APC-beta-catenin complex)|go:""GO:0035089""(establishment of apical/basal cell polarity)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042060""(wound healing)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043615""(astrocyte cell migration)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060561""(apoptotic process involved in morphogenesis)|go:""GO:0060603""(mammary gland duct morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098793""(presynapse)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098968""(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099147""(extrinsic component of postsynaptic density membrane)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|interpro:IPR050614|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|rcsb pdb:7QRS|rcsb pdb:7QRT|rcsb pdb:7QS8|rcsb pdb:7QS9|rcsb pdb:7QSA|rcsb pdb:7QSB|rcsb pdb:7QTO|rcsb pdb:7QTP|rcsb pdb:7QTU|rcsb pdb:8B82|rcsb pdb:8B87|rcsb pdb:8B8O|rcsb pdb:8B9T|rcsb pdb:8BIA|rcsb pdb:8BJ0|rcsb pdb:8CD3|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270|dip:DIP-31259N|panther:PTHR23119(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:xHNrql5wX2JZV+9YxFGM7gm1/CY9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q5VYK3	intact:EBI-27055528	intact:EBI-521451|uniprotkb:A0A804HJA4|uniprotkb:B3KXF2|uniprotkb:O15074|uniprotkb:Q8WU82	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ecm29_human(display_long)|uniprotkb:ECPAS(gene name)|psi-mi:ECPAS(display_short)|uniprotkb:ECM29(gene name synonym)|uniprotkb:Ecm29 proteasome adapter and scaffold(gene name synonym)|uniprotkb:KIAA0368(gene name synonym)|uniprotkb:Proteasome-associated protein ECM29 homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_005251908.1|refseq:XP_005251909.1|refseq:XP_005251910.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024372|mint:Q5VYK3|refseq:XP_005251907.1|go:""GO:0000502""(proteasome complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005813""(centrosome)|go:""GO:0016020""(membrane)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0036503""(ERAD pathway)|go:""GO:0043248""(proteasome assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070628""(proteasome binding)|panther:PTHR23346(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:lBqnwI2OO2aNvK1kjEpYOGK4oUI9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q92973	intact:EBI-27055528	intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712.5|intact:EBI-21356909	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000083312.19(gene)|ensembl:ENST00000337273.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|rcsb pdb:7VPW|rcsb pdb:8SGH|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933|refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|panther:PTHR10527(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9BTT6	intact:EBI-27055528	intact:EBI-713489|uniprotkb:Q9HAC0|uniprotkb:Q9NVF1|uniprotkb:Q5TGN3|ensembl:ENSP00000359925.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:lrrc1_human(display_long)|uniprotkb:LAP and no PDZ protein(gene name synonym)|uniprotkb:LANO adapter protein(gene name synonym)|uniprotkb:LRRC1(gene name)|psi-mi:LRRC1(display_short)|uniprotkb:LANO(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_060684.4|refseq:XP_011513028.1|ensembl:ENSG00000137269.15(gene)|ensembl:ENST00000370888.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050614|mint:Q9BTT6|reactome:R-HSA-9696270|panther:PTHR48051(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:FJ/8+gehIT2j2bJ8gYpkDht+//I9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y4R8	intact:EBI-27055528	intact:EBI-1043674|uniprotkb:O75168|uniprotkb:Q7LDV4|uniprotkb:Q9BR21|intact:EBI-725566|intact:EBI-1047721|uniprotkb:D3DU73|ensembl:ENSP00000262319.6	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:telo2_human(display_long)|uniprotkb:TELO2(gene name)|psi-mi:TELO2(display_short)|uniprotkb:KIAA0683(gene name synonym)|uniprotkb:Protein clk-2 homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:488642""|dip:DIP-40568N|ensembl:ENSG00000100726.15(gene)|ensembl:ENST00000262319.11(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0110078""(TTT Hsp90 cochaperone complex)|go:""GO:2000003""(positive regulation of DNA damage checkpoint)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019337|interpro:IPR038528|interpro:IPR051970|mint:Q9Y4R8|rcsb pdb:4PSI|rcsb pdb:7F4U|rcsb pdb:7OLE|refseq:NP_057195.2|refseq:XP_016879403.1|panther:PTHR15830(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:AnKk5b5Bc/tzEEz+p68m5uQUZVY9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y2L1	intact:EBI-27055528	intact:EBI-373539|uniprotkb:A6NI21|uniprotkb:Q5W0P7|uniprotkb:Q5W0P8|uniprotkb:Q658Z7|uniprotkb:Q7Z481|uniprotkb:Q8WWI2|uniprotkb:Q9UG36|uniprotkb:B2RBL2|ensembl:ENSP00000366997.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:rrp44_human(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Protein DIS3 homolog(gene name synonym)|uniprotkb:KIAA1008(gene name synonym)|uniprotkb:RRP44(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001121698.1|refseq:NP_055768.3|ensembl:ENSG00000083520.15(gene)|ensembl:ENST00000377767.9(transcript)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000176""(""nuclear exosome (RNase complex)"")|go:""GO:0000177""(""cytoplasmic exosome (RNase complex)"")|go:""GO:0000178""(""exosome (RNase complex)"")|go:""GO:0000288""(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:0003723""(RNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006364""(rRNA processing)|go:""GO:0006396""(RNA processing)|go:""GO:0006401""(RNA catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016075""(rRNA catabolic process)|go:""GO:0071031""(nuclear mRNA surveillance of mRNA 3'-end processing)|go:""GO:0071034""(CUT catabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|interpro:IPR050180|mint:Q9Y2L1|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|panther:PTHR23355(orthology-group)|ensembl:ENSP00000366997.4|ensembl:ENST00000377780.8|ensembl:ENSP00000367011.4"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:cHOcZh1JkvywNK4Tq2DUvPMm6kc9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P68133	intact:EBI-27055528	intact:EBI-367510|uniprotkb:P02568|uniprotkb:P99020|uniprotkb:Q5T8M9|ensembl:ENSP00000355645.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:acts_human(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:171430""|efo:""Orphanet:171433""|efo:""Orphanet:171436""|efo:""Orphanet:171439""|efo:""Orphanet:2020""|efo:""Orphanet:447977""|efo:""Orphanet:97240""|efo:""Orphanet:97244""|efo:""Orphanet:98904""|panther:PTHR11937(orthology-group)|ensembl:ENSG00000143632.15(gene)|ensembl:ENST00000366684.7(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005865""(striated muscle thin filament)|go:""GO:0005884""(actin filament)|go:""GO:0006936""(muscle contraction)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016787""(hydrolase activity)|go:""GO:0017022""(myosin binding)|go:""GO:0030017""(sarcomere)|go:""GO:0030027""(lamellipodium)|go:""GO:0030175""(filopodium)|go:""GO:0030240""(skeletal muscle thin filament assembly)|go:""GO:0035865""(cellular response to potassium ion)|go:""GO:0043503""(skeletal muscle fiber adaptation)|go:""GO:0043531""(ADP binding)|go:""GO:0044297""(cell body)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0048741""(skeletal muscle fiber development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0090131""(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68133|rcsb pdb:7RNS|rcsb pdb:7RNU|rcsb pdb:7RNV|rcsb pdb:9DUU|rcsb pdb:9DUV|reactome:R-HSA-390522|refseq:NP_001091.1"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9NUU7	intact:EBI-27055528	intact:EBI-740301|uniprotkb:Q53FM0|uniprotkb:B2RPL0|uniprotkb:B4DRZ7|ensembl:ENSP00000306117.7	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:dd19a_human(display_long)|uniprotkb:DEAD box protein 19A(gene name synonym)|uniprotkb:DDX19-like protein(gene name synonym)|uniprotkb:DDX19A(gene name)|psi-mi:DDX19A(display_short)|uniprotkb:DDX19L(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_060802.1|refseq:NP_001307451.1|refseq:NP_001307454.1|refseq:NP_001307455.1|refseq:NP_001307456.1|ensembl:ENSG00000168872.17(gene)|ensembl:ENST00000302243.12(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0010043""(response to zinc ion)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9NUU7|panther:PTHR47958(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Uvjex/lODTGHjNguDqyaquwkNaw9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O14617	intact:EBI-27055528	intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:664511""|dip:DIP-46793N|ensembl:ENSG00000065000.20(gene)|ensembl:ENST00000345016.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016182""(synaptic vesicle budding from endosome)|go:""GO:0016183""(synaptic vesicle coating)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0032438""(melanosome organization)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0043195""(terminal bouton)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046907""(intracellular transport)|go:""GO:0048007""(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0048499""(synaptic vesicle membrane organization)|go:""GO:0051138""(positive regulation of NK T cell differentiation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140916""(zinc ion import into lysosome)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|refseq:NP_001248755.1|refseq:NP_003929.4|efo:""Orphanet:1000""|efo:""Orphanet:54""|panther:PTHR22781(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q29RF7	intact:EBI-27055528	intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427.8	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|panther:PTHR12663(orthology-group)|refseq:XP_016863417.1|dip:DIP-35419N|ensembl:ENSG00000121892.15(gene)|ensembl:ENST00000303538.13(transcript)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0008156""(negative regulation of DNA replication)|go:""GO:0051301""(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q96T76	intact:EBI-27055528	intact:EBI-1044169|uniprotkb:Q9BYS9|uniprotkb:Q17RZ8|uniprotkb:Q5T455|uniprotkb:Q66K82|uniprotkb:Q7L4W8|uniprotkb:Q969Z1|uniprotkb:Q96DF1|uniprotkb:Q96MR1|uniprotkb:Q96RK5|uniprotkb:Q96SK1|uniprotkb:Q9BUE2|uniprotkb:D3DR55|uniprotkb:B0QZ75|uniprotkb:B3KPE5|uniprotkb:B4DQX2|uniprotkb:B4E2I3|uniprotkb:F8W9Y2|ensembl:ENSP00000359818.1|ensembl:ENSP00000412698.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mms19_human(display_long)|uniprotkb:MMS19(gene name)|psi-mi:MMS19(display_short)|uniprotkb:MMS19L(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_071757.4|refseq:NP_001276332.1|refseq:NP_001276333.1|refseq:NP_001276334.1|refseq:NP_001317057.1|refseq:XP_016872013.1|ensembl:ENSG00000155229.21(gene)|ensembl:ENST00000370782.6(transcript)|ensembl:ENST00000438925.7(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005675""(transcription factor TFIIH holo complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0007059""(chromosome segregation)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0071817""(MMXD complex)|go:""GO:0097361""(cytosolic [4Fe-4S] assembly targeting complex)|go:""GO:0097428""(obsolete protein maturation by iron-sulfur cluster transfer)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|mint:Q96T76|reactome:R-HSA-2564830|panther:PTHR12891(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:sujw9MQiwau6A0dumVM7gXVMGjE9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q7Z4H3	intact:EBI-27055528	intact:EBI-6163836|uniprotkb:Q5TDQ4|uniprotkb:Q6NZ49|uniprotkb:Q9BTT2|uniprotkb:Q9BV31|uniprotkb:Q9Y3D1|ensembl:ENSP00000381220.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:hddc2_human(display_long)|uniprotkb:CGI-130(orf name)|uniprotkb:HDDC2(gene name)|psi-mi:HDDC2(display_short)|uniprotkb:C6orf74(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 2(gene name synonym)|uniprotkb:NS5ATP2(gene name synonym)|uniprotkb:HD domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_057147.2|ensembl:ENSG00000111906.18(gene)|ensembl:ENST00000398153.7(transcript)|go:""GO:0002953""(5'-deoxynucleotidase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR039356|mint:Q7Z4H3|rcsb pdb:4DMB|rcsb pdb:4L1J|rcsb pdb:4L7E|rcsb pdb:4L7W|panther:PTHR11845(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:8f3lTUUoG5pAau6LGaxmi1qS6lU9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O14950	intact:EBI-27055528	intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500.5|ensembl:ENSP00000383037.5|ensembl:ENSP00000463559.1|ensembl:ENSP00000464464.1|ensembl:ENSP00000496809.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680.14(gene)|ensembl:ENST00000237500.10(transcript)|ensembl:ENST00000400175.9(transcript)|ensembl:ENST00000581193.5(transcript)|ensembl:ENST00000584539.1(transcript)|ensembl:ENST00000648965.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016460""(myosin II complex)|go:""GO:0030016""(myofibril)|go:""GO:0030018""(Z disc)|go:""GO:0032036""(myosin heavy chain binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|interpro:IPR050403|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|panther:PTHR23049(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O75155	intact:EBI-27055528	intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712.13(gene)|ensembl:ENST00000456430.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0010265""(SCF complex assembly)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017025""(TBP-class protein binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013932(""TATA-binding protein interacting (TIP20)"")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155|panther:PTHR12696(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9BSD7	intact:EBI-27055528	intact:EBI-2689235|ensembl:ENSP00000355587.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ntpcr_human(display_long)|uniprotkb:Nucleoside triphosphate phosphohydrolase(gene name synonym)|uniprotkb:NTPCR(gene name)|psi-mi:NTPCR(display_short)|uniprotkb:C1orf57(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_115700.1|refseq:NP_001316382.1|ensembl:ENSG00000135778.12(gene)|ensembl:ENST00000366628.10(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017111""(ribonucleoside triphosphate phosphatase activity)|go:""GO:0043273""(CTPase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004948(Protein of unknown function DUF265)|interpro:IPR027417|mint:Q9BSD7|rcsb pdb:2I3B|panther:PTHR43146(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:tJoP+XQzoa4urq6g1rdZhMWO49g9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P84095	intact:EBI-27055528	intact:EBI-446579|uniprotkb:P35238|uniprotkb:Q8NI04|ensembl:ENSP00000339467.4|ensembl:ENSP00000380175.1|ensembl:ENSP00000380176.1|ensembl:ENSP00000436932.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:rhog_human(display_long)|uniprotkb:RHOG(gene name)|psi-mi:RHOG(display_short)|uniprotkb:ARHG(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001656.2|ensembl:ENSG00000177105.10(gene)|ensembl:ENST00000351018.5(transcript)|ensembl:ENST00000396978.1(transcript)|ensembl:ENST00000396979.1(transcript)|ensembl:ENST00000533217.1(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0042995""(cell projection)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1900027""(regulation of ruffle assembly)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR042734|mint:P84095|rcsb pdb:6UKA|rcsb pdb:7Y4A|rcsb pdb:8XM7|rcsb pdb:8ZJ2|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-5625970|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-9013408|refseq:XP_005252973.1|refseq:XP_016873208.1|panther:PTHR24072(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:9PItVl1k5j6JhIDqwqcov1E/N8w9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9NXH9	intact:EBI-27055528	intact:EBI-748900|uniprotkb:O76103|uniprotkb:Q548Y5|uniprotkb:Q8WVA6|intact:EBI-21355876|ensembl:ENSP00000350352.4|ensembl:ENSP00000416149.1|ensembl:ENSP00000466967.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	"psi-mi:trm1_human(display_long)|uniprotkb:""tRNA(guanine-26,N(2)-N(2)) methyltransferase""(gene name synonym)|uniprotkb:tRNA 2,2-dimethylguanosine-26 methyltransferase(gene name synonym)|uniprotkb:""tRNA(m(2,2)G26)dimethyltransferase""(gene name synonym)|uniprotkb:TRMT1(gene name)|psi-mi:TRMT1(display_short)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:528084""|ensembl:ENSG00000104907.13(gene)|ensembl:ENST00000357720.9(transcript)|ensembl:ENST00000437766.5(transcript)|ensembl:ENST00000592062.5(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002940""(tRNA N2-guanine methylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006400""(tRNA modification)|go:""GO:0046872""(metal ion binding)|go:""GO:0160104""(""tRNA (guanine(26)-N2)-dimethyltransferase activity"")|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002905(N2,N2-dimethylguanosine tRNA methyltransferase)|interpro:IPR029063|interpro:IPR036855|interpro:IPR042296|mint:Q9NXH9|rcsb pdb:9DW6|reactome:R-HSA-6782315|refseq:NP_001129507.1|refseq:NP_001136026.1|refseq:NP_060192.1|refseq:XP_016882433.1|refseq:XP_016882434.1|panther:PTHR10631(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:ty0oTgEETLwZTnDb1RFHkrkCQsU9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q6P1J9	intact:EBI-27055528	intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000134371.15(gene)|ensembl:ENST00000367435.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001711""(endodermal cell fate commitment)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016593""(Cdc73/Paf1 complex)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0031442""(positive regulation of mRNA 3'-end processing)|go:""GO:0031648""(protein destabilization)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045638""(negative regulation of myeloid cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:1902808""(positive regulation of cell cycle G1/S phase transition)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|rcsb pdb:7OOP|rcsb pdb:7OPC|rcsb pdb:7OPD|rcsb pdb:7UNC|rcsb pdb:7UND|rcsb pdb:8A3Y|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_078805.3|dip:DIP-37884N|efo:""Orphanet:99880""|efo:""Orphanet:143""|efo:""Orphanet:99879""|ensembl:ENSP00000356405.4|panther:PTHR12466(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y5A9	intact:EBI-27055528	intact:EBI-2878081|uniprotkb:B4E1G7|uniprotkb:A6NKG4|uniprotkb:Q5VSZ9|uniprotkb:Q8TDH0|uniprotkb:Q9BUJ5|uniprotkb:A8K966|uniprotkb:D3DPM8|ensembl:ENSP00000362918.3|ensembl:ENSP00000444660.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ythd2_human(display_long)|uniprotkb:HGRG8(gene name synonym)|uniprotkb:CLL-associated antigen KW-14(gene name synonym)|uniprotkb:High-glucose-regulated protein 8(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-2(gene name synonym)|uniprotkb:YTHDF2(gene name)|psi-mi:YTHDF2(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001166299.1|refseq:NP_001166599.1|refseq:NP_057342.2|ensembl:ENSG00000198492.16(gene)|ensembl:ENST00000373812.8(transcript)|ensembl:ENST00000542507.5(transcript)|go:""GO:0000932""(P-body)|go:""GO:0001556""(oocyte maturation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0006959""(humoral immune response)|go:""GO:0007276""(gamete generation)|go:""GO:0007284""(spermatogonial cell division)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0034063""(stress granule assembly)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0045087""(innate immune response)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0048598""(embryonic morphogenesis)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0061157""(mRNA destabilization)|go:""GO:0062153""(C5-methylcytidine-containing RNA reader activity)|go:""GO:0070925""(organelle assembly)|go:""GO:0071425""(hematopoietic stem cell proliferation)|go:""GO:0098508""(endothelial to hematopoietic transition)|go:""GO:1902036""(regulation of hematopoietic stem cell differentiation)|go:""GO:1903538""(regulation of meiotic cell cycle process involved in oocyte maturation)|go:""GO:1903679""(positive regulation of cap-independent translational initiation)|go:""GO:1990247""(N6-methyladenosine-containing RNA reader activity)|go:""GO:2000232""(regulation of rRNA processing)|go:""GO:2000737""(negative regulation of stem cell differentiation)|interpro:IPR007275(YT521-B-like protein)|interpro:IPR045168|mint:Q9Y5A9|rcsb pdb:4RDN|rcsb pdb:4RDO|rcsb pdb:4WQN|rcsb pdb:7A1V|rcsb pdb:7BIK|rcsb pdb:7R5F|rcsb pdb:7R5L|rcsb pdb:7R5W|rcsb pdb:7YWB|rcsb pdb:7YX6|rcsb pdb:7YXE|rcsb pdb:7Z26|rcsb pdb:7Z4U|rcsb pdb:7Z54|rcsb pdb:7Z5M|rcsb pdb:7Z7B|rcsb pdb:7Z7F|rcsb pdb:7Z8P|rcsb pdb:7Z8W|rcsb pdb:7Z8X|rcsb pdb:7Z92|rcsb pdb:7Z93|rcsb pdb:7ZG4|panther:PTHR12357(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:PF4C2t/728HqnrTyBQDJydH0G709606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8TC12	intact:EBI-27055528	intact:EBI-2823756|uniprotkb:Q0QD40|uniprotkb:B4DDW0|uniprotkb:A8K062|uniprotkb:B2RB26|uniprotkb:A6NDK3|uniprotkb:Q6IAH5|uniprotkb:Q9NRW0|uniprotkb:Q9Y391|ensembl:ENSP00000370750.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:rdh11_human(display_long)|uniprotkb:RDH11(gene name)|psi-mi:RDH11(display_short)|uniprotkb:ARSDR1(gene name synonym)|uniprotkb:PSDR1(gene name synonym)|uniprotkb:Androgen-regulated short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:HCV core-binding protein HCBP12(gene name synonym)|uniprotkb:Prostate short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:Retinal reductase 1(gene name synonym)|uniprotkb:SDR7C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 7C member 1(gene name synonym)|uniprotkb:CGI-82(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000072042.13(gene)|ensembl:ENST00000381346.9(transcript)|go:""GO:0001523""(retinoid metabolic process)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0004745""(""all-trans-retinol dehydrogenase (NAD+) activity"")|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007601""(visual perception)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0033721""(""aldehyde dehydrogenase (NADP+) activity"")|go:""GO:0042572""(retinol metabolic process)|go:""GO:0042574""(retinal metabolic process)|go:""GO:0052650""(""all-trans-retinol dehydrogenase (NADP+) activity"")|go:""GO:0102354""(11-cis-retinol dehydrogenase activity)|go:""GO:0110095""(cellular detoxification of aldehyde)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q8TC12|reactome:R-HSA-2453902|reactome:R-HSA-5365859|reactome:R-HSA-975634|refseq:NP_001239579.1|refseq:NP_057110.3|efo:""Orphanet:436245""|panther:PTHR24320(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:elUutgO+T5gnwthTzc4WDetnuug9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P09525	intact:EBI-27055528	intact:EBI-2556852|uniprotkb:Q9BWK1|uniprotkb:Q96F33|uniprotkb:B4DDF9|intact:EBI-10250835|intact:EBI-13351437|uniprotkb:Q6LES2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:anxa4_human(display_long)|uniprotkb:ANX4(gene name synonym)|uniprotkb:Annexin-4(gene name synonym)|uniprotkb:Annexin IV(gene name synonym)|uniprotkb:Lipocortin IV(gene name synonym)|uniprotkb:Endonexin I(gene name synonym)|uniprotkb:Chromobindin-4(gene name synonym)|uniprotkb:Protein II(gene name synonym)|uniprotkb:P32.5(gene name synonym)|uniprotkb:Placental anticoagulant protein II(gene name synonym)|uniprotkb:PP4-X(gene name synonym)|uniprotkb:35-beta calcimedin(gene name synonym)|uniprotkb:Carbohydrate-binding protein p33/p41(gene name synonym)|uniprotkb:ANXA4(gene name)|psi-mi:ANXA4(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001144.1|refseq:NP_001307627.1|refseq:NP_001307629.1|refseq:NP_001307631.1|refseq:XP_016859432.1|refseq:XP_016859433.1|interpro:IPR001464(Annexin)|interpro:IPR002391(Annexin, type IV)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P09525|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0004859""(phospholipase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007165""(signal transduction)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0009986""(cell surface)|go:""GO:0012506""(vesicle membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|rcsb pdb:2ZOC|panther:PTHR10502(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:9FM1bXFxch8Srj1njfDiNXtowDU9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9BRX2	intact:EBI-27055528	intact:EBI-1043580|uniprotkb:Q9GZS6|uniprotkb:Q9Y306|ensembl:ENSP00000274311.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pelo_human(display_long)|uniprotkb:PELO(gene name)|psi-mi:PELO(display_short)|uniprotkb:Protein Dom34 homolog(gene name synonym)|uniprotkb:CGI-17(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_057030.3|ensembl:ENSG00000152684.11(gene)|ensembl:ENST00000274311.3(transcript)|go:""GO:0001833""(inner cell mass cell proliferation)|go:""GO:0005737""(cytoplasm)|go:""GO:0006417""(regulation of translation)|go:""GO:0007492""(endoderm development)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0043022""(ribosome binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051276""(chromosome organization)|go:""GO:0051301""(cell division)|go:""GO:0060231""(mesenchymal to epithelial transition)|go:""GO:0060589""(nucleoside-triphosphatase regulator activity)|go:""GO:0070481""(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:""GO:0070651""(nonfunctional rRNA decay)|go:""GO:0070966""(nuclear-transcribed mRNA catabolic process, no-go decay)|go:""GO:0071025""(RNA surveillance)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0170011""(stalled ribosome sensor activity)|go:""GO:1990533""(Dom34-Hbs1 complex)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|mint:Q9BRX2|rcsb pdb:1X52|rcsb pdb:5EO3|rcsb pdb:5LZW|rcsb pdb:5LZX|rcsb pdb:5LZY|rcsb pdb:5LZZ|panther:PTHR10853(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:EZIi8JN2tu0u4oH06fOus3LKjoo9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P11172	intact:EBI-27055528	intact:EBI-723452|uniprotkb:O00758|uniprotkb:O00759|uniprotkb:O00760|uniprotkb:Q16862|uniprotkb:Q9H3Q2|uniprotkb:Q9UG49|uniprotkb:B5LY68|uniprotkb:B5LY72|ensembl:ENSP00000232607.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:umps_human(display_long)|uniprotkb:UMPS(gene name)|psi-mi:UMPS(display_short)|uniprotkb:OK/SW-cl.21(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000114491.14(gene)|ensembl:ENST00000232607.7(transcript)|go:""GO:0004588""(orotate phosphoribosyltransferase activity)|go:""GO:0004590""(orotidine-5'-phosphate decarboxylase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|rcsb pdb:2JGY|go:""GO:0005829""(cytosol)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006222""(UMP biosynthetic process)|go:""GO:0006225""(UDP biosynthetic process)|go:""GO:0007565""(female pregnancy)|go:""GO:0007595""(lactation)|go:""GO:0019856""(pyrimidine nucleobase biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR001754(Orotidine 5'-phosphate decarboxylase, core)|interpro:IPR004467(Orotate phosphoribosyl transferase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR014732(Orotidine 5'-phosphate decarboxylase, subfamily 1, core)|interpro:IPR018089|interpro:IPR023031|interpro:IPR029057|mint:P11172|rcsb pdb:2EAW|rcsb pdb:2P1F|rcsb pdb:2QCC|rcsb pdb:2QCD|rcsb pdb:2QCE|rcsb pdb:2QCF|rcsb pdb:2QCG|rcsb pdb:2QCH|rcsb pdb:2QCL|rcsb pdb:2QCM|rcsb pdb:2QCN|rcsb pdb:2V30|rcsb pdb:2WNS|rcsb pdb:3BGG|rcsb pdb:3BGJ|rcsb pdb:3BK0|rcsb pdb:3BVJ|rcsb pdb:3DBP|rcsb pdb:3EWU|rcsb pdb:3EWW|rcsb pdb:3EWX|rcsb pdb:3EWY|rcsb pdb:3EWZ|rcsb pdb:3EX1|rcsb pdb:3EX2|rcsb pdb:3EX3|rcsb pdb:3EX4|rcsb pdb:3EX6|rcsb pdb:3G3D|rcsb pdb:3G3M|rcsb pdb:3L0K|rcsb pdb:3L0N|rcsb pdb:3MI2|rcsb pdb:3MO7|rcsb pdb:3MW7|rcsb pdb:4HIB|rcsb pdb:4HKP|rcsb pdb:6YVK|rcsb pdb:6YVL|rcsb pdb:6YVM|rcsb pdb:6YVN|rcsb pdb:6YVO|rcsb pdb:6YWT|rcsb pdb:6YWU|rcsb pdb:6ZWY|rcsb pdb:6ZWZ|rcsb pdb:6ZX0|rcsb pdb:6ZX1|rcsb pdb:6ZX2|rcsb pdb:6ZX3|rcsb pdb:7AM9|rcsb pdb:7ASQ|rcsb pdb:7OQF|rcsb pdb:7OQI|rcsb pdb:7OQK|rcsb pdb:7OQM|rcsb pdb:7OQN|rcsb pdb:7OTU|rcsb pdb:7OUZ|rcsb pdb:7OV0|rcsb pdb:7Q1H|reactome:R-HSA-500753|refseq:NP_000364.1|dip:DIP-29595N|efo:""Orphanet:30""|panther:PTHR19278(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:8HKx6eTv3pMPMJQzUhhFjyGXGZI9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O94906	intact:EBI-27055528	intact:EBI-536755|uniprotkb:O95109|uniprotkb:Q5VXS5|uniprotkb:Q9H3Z1|uniprotkb:Q9H4T9|uniprotkb:Q9H4U8|uniprotkb:Q9NTE6|uniprotkb:B2RAR5|uniprotkb:B3KMC6|ensembl:ENSP00000266079.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:prp6_human(display_long)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:PRPF6(gene name)|psi-mi:PRPF6(display_short)|uniprotkb:C20orf14(gene name synonym)|uniprotkb:Androgen receptor N-terminal domain-transactivating protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR11246(orthology-group)|ensembl:ENSG00000101161.8(gene)|ensembl:ENST00000266079.5(transcript)|go:""GO:0000244""(spliceosomal tri-snRNP complex assembly)|go:""GO:0000245""(spliceosomal complex assembly)|go:""GO:0000375""(RNA splicing, via transesterification reactions)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005682""(U5 snRNP)|go:""GO:0006403""(RNA localization)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR045075|mint:O94906|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8Q7N|rcsb pdb:8Q7Q|rcsb pdb:8Q7V|rcsb pdb:8Q7W|rcsb pdb:8Q7X|rcsb pdb:8Q91|rcsb pdb:8QO9|rcsb pdb:8QOZ|rcsb pdb:8QP8|rcsb pdb:8QP9|rcsb pdb:8QPA|rcsb pdb:8QPB|rcsb pdb:8QPE|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RC0|rcsb pdb:8RM5|rcsb pdb:8Y6O|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_036601.2|dip:DIP-29006N|efo:""Orphanet:791""|ensembl:ENSP00000266079.4"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:M5ovIXl+1ob6VSKbXZUGU73J7Jk9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9BXJ9	intact:EBI-27055528	intact:EBI-1042540|uniprotkb:Q52LG9|uniprotkb:Q8IWH4|uniprotkb:Q8NEV2|uniprotkb:Q9H8P6|uniprotkb:D3DNY6|ensembl:ENSP00000296543.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:naa15_human(display_long)|uniprotkb:NAA15(gene name)|psi-mi:NAA15(display_short)|uniprotkb:GA19(gene name synonym)|uniprotkb:NATH(gene name synonym)|uniprotkb:TBDN100(gene name synonym)|uniprotkb:Gastric cancer antigen Ga19(gene name synonym)|uniprotkb:N-terminal acetyltransferase(gene name synonym)|uniprotkb:Protein tubedown-1(gene name synonym)|uniprotkb:Tbdn100(gene name synonym)|uniprotkb:NARG1(gene name synonym)|uniprotkb:NMDA receptor-regulated protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:528084""|ensembl:ENSG00000164134.14(gene)|ensembl:ENST00000296543.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006474""(N-terminal protein amino acid acetylation)|go:""GO:0010698""(acetyltransferase activator activity)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0030154""(cell differentiation)|go:""GO:0031415""(NatA complex)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0050821""(protein stabilization)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|mint:Q9BXJ9|rcsb pdb:6C95|rcsb pdb:6C9M|rcsb pdb:6PPL|rcsb pdb:6PW9|rcsb pdb:9F1B|rcsb pdb:9F1C|rcsb pdb:9F1D|rcsb pdb:9FPZ|refseq:NP_476516.1|panther:PTHR22767(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:BGW5jQRBYXuf75thzj6cWvL2A5Y9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O00232	intact:EBI-27055528	intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|uniprotkb:A6NP15|ensembl:ENSP00000348442.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:528084""|efo:""Orphanet:529962""|interpro:IPR036388|ensembl:ENSG00000197170.10(gene)|ensembl:ENST00000356126.8(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005838""(proteasome regulatory particle)|go:""GO:0008541""(proteasome regulatory particle, lid subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|interpro:IPR054559|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-5676590|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|refseq:NP_001303270.1|refseq:NP_002807.1|refseq:NP_777360.1|dip:DIP-27549N|panther:PTHR10855(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q6UB35	intact:EBI-27055528	intact:EBI-1046835|uniprotkb:Q2TBF3|uniprotkb:Q8WVW0|uniprotkb:Q96HG8|uniprotkb:Q9H789|uniprotkb:Q9UFU8|ensembl:ENSP00000356290.3|intact:EBI-28986171	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:c1tm_human(display_long)|uniprotkb:MTHFD1L(gene name)|psi-mi:MTHFD1L(display_short)|uniprotkb:FTHFSDC1(gene name synonym)|uniprotkb:Formyltetrahydrofolate synthetase(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001229696.1|refseq:NP_001229697.1|refseq:NP_001229698.1|refseq:NP_056255.2|ensembl:ENSG00000120254.16(gene)|ensembl:ENST00000367321.8(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0004329""(formate-tetrahydrofolate ligase activity)|go:""GO:0004488""(""methylenetetrahydrofolate dehydrogenase (NADP+) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006760""(folic acid-containing compound metabolic process)|go:""GO:0009257""(10-formyltetrahydrofolate biosynthetic process)|go:""GO:0015942""(formate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048702""(embryonic neurocranium morphogenesis)|go:""GO:0048703""(embryonic viscerocranium morphogenesis)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR027417|interpro:IPR036291|interpro:IPR046346|mint:Q6UB35|reactome:R-HSA-196757|panther:PTHR48099(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:lJRND1kcMEF99+fT1b+X8hfuLHM9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O43324	intact:EBI-27055528	intact:EBI-1048486|uniprotkb:Q5THS2|ensembl:ENSP00000369038.5|uniprotkb:C9JLK5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mca3_human(display_long)|uniprotkb:Multisynthase complex auxiliary component p18(gene name synonym)|uniprotkb:Elongation factor p18(gene name synonym)|uniprotkb:EEF1E1(gene name)|psi-mi:EEF1E1(display_short)|uniprotkb:P18(gene name synonym)|uniprotkb:AIMP3(gene name synonym)|uniprotkb:Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001129122.1|refseq:NP_004271.1|ensembl:ENSG00000124802.12(gene)|ensembl:ENST00000379715.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0017101""(aminoacyl-tRNA synthetase multienzyme complex)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043517""(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2001235""(positive regulation of apoptotic signaling pathway)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036282|interpro:IPR042450|interpro:IPR053836|interpro:IPR053837|mint:O43324|rcsb pdb:2UZ8|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5BMU|rcsb pdb:5Y6L|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-9856649|dip:DIP-50581N|panther:PTHR44490(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:4AuJouC9q6uAH/4EH8SKSPHyEZU9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8NI60	intact:EBI-27055528	intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:139485""|ensembl:ENSG00000163050.18(gene)|ensembl:ENST00000366777.4(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0016310""(phosphorylation)|go:""GO:0043531""(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034646|interpro:IPR051409|mint:Q8NI60|rcsb pdb:4PED|rcsb pdb:5I35|rcsb pdb:7UDP|rcsb pdb:7UDQ|reactome:R-HSA-2142789|refseq:NP_064632.2|refseq:XP_005273258.1|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_016857341.1|panther:PTHR43851(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y263	intact:EBI-27055528	intact:EBI-1994037|ensembl:ENSP00000380460.3|uniprotkb:Q53EU5|uniprotkb:Q5VY33|uniprotkb:Q9NUL8|uniprotkb:Q9NVE9|uniprotkb:Q9UF53|uniprotkb:Q9Y5L1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:plap_human(display_long)|uniprotkb:PLAA(gene name)|psi-mi:PLAA(display_short)|uniprotkb:PLAP(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000137055.15(gene)|ensembl:ENST00000397292.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006644""(phospholipid metabolic process)|go:""GO:0006693""(prostaglandin metabolic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0010992""(ubiquitin recycling)|go:""GO:0016005""(phospholipase A2 activator activity)|go:""GO:0016236""(macroautophagy)|go:""GO:0032430""(positive regulation of phospholipase A2 activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0045202""(synapse)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:1900045""(negative regulation of protein K63-linked ubiquitination)|go:""GO:1903423""(positive regulation of synaptic vesicle recycling)|go:""GO:1903861""(positive regulation of dendrite extension)|go:""GO:2001224""(positive regulation of neuron migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013535(PUL)|interpro:IPR015155(""PFU (PLAA family ubiquitin binding)"")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036322|interpro:IPR038122|mint:Q9Y263|rcsb pdb:2K89|rcsb pdb:2K8A|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:3EBB|refseq:NP_001026859.1|panther:PTHR19849(orthology-group)|efo:""Orphanet:521426"""	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:SoClA00UzZpX9vV1cJWvefY6eY89606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P62158	intact:EBI-27055528	intact:EBI-397435|uniprotkb:P02593|uniprotkb:Q53S29|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:calm_human(display_short)|psi-mi:P62158(display_long)|uniprotkb:CALM1(gene name)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:1304""(molecule set)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:""GO:0002027""(regulation of heart rate)|go:""GO:0005513""(detection of calcium ion)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0030017""(sarcomere)|go:""GO:0030801""(obsolete positive regulation of cyclic nucleotide metabolic process)|go:""GO:0032516""(obsolete positive regulation of phosphoprotein phosphatase activity)|go:""GO:0035307""(obsolete positive regulation of protein dephosphorylation)|go:""GO:0051343""(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005876""(spindle microtubule)|go:""GO:0000922""(spindle pole)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0006936""(muscle contraction)|go:""GO:0060315""(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0002576""(platelet degranulation)|go:""GO:0060316""(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0050999""(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:""GO:0010801""(negative regulation of peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031954""(positive regulation of protein autophosphorylation)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0000165""(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:5COC|go:""GO:0021762""(substantia nigra development)|go:""GO:0070062""(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|rcsb pdb:4GOW|rcsb pdb:4Q57|go:""GO:0043647""(inositol phosphate metabolic process)|go:""GO:0022400""(regulation of opsin-mediated signaling pathway)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0005576""(extracellular region)|go:""GO:0031997""(obsolete N-terminal myristoylation domain binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0010880""(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031432""(titin binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051592""(response to calcium ion)|go:""GO:0055117""(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:""GO:0005088""|go:""GO:0007223""(Wnt signaling pathway, calcium modulating pathway)|go:""GO:0008440""(inositol-1,4,5-trisphosphate 3-kinase activity)|go:""GO:0015276""(ligand-gated monoatomic ion channel activity)|go:""GO:0005634""(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:4UMO|rcsb pdb:4V0C|go:""GO:0031982""(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|refseq:NP_001292555.1|rcsb pdb:4OVN|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|rcsb pdb:5DBR|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0001975""(response to amphetamine)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0030235""(nitric-oxide synthase regulator activity)|go:""GO:0030426""(growth cone)|go:""GO:0051000""(positive regulation of nitric-oxide synthase activity)|go:""GO:0051412""(response to corticosterone)|go:""GO:1901841""(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:""GO:0032991""(protein-containing complex)|go:""GO:0006479""(protein methylation)|go:""GO:0014069""(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0043388""(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:""GO:0034704""(calcium channel complex)|go:""GO:0010856""(adenylate cyclase activator activity)|go:""GO:0051186""(obsolete cofactor metabolic process)|go:""GO:0075206""(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:""GO:0060314""(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:""GO:1902494""(catalytic complex)|go:""GO:0043234""|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0030819""(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:""GO:0019722""(calcium-mediated signaling)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:""GO:0005623""(obsolete cell)|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|rcsb pdb:6HR1|rcsb pdb:6OS4|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0016032""(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	-	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P06132	intact:EBI-27055528	intact:EBI-2871776|uniprotkb:Q9BUZ0|uniprotkb:Q16863|uniprotkb:Q6IB28|uniprotkb:Q53YB8|uniprotkb:A8K762|uniprotkb:Q16883|uniprotkb:Q53ZP6|ensembl:ENSP00000246337.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:dcup_human(display_long)|uniprotkb:UROD(gene name)|psi-mi:UROD(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:443062""|efo:""Orphanet:95159""|ensembl:ENSG00000126088.14(gene)|ensembl:ENST00000246337.9(transcript)|go:""GO:0004853""(uroporphyrinogen decarboxylase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006778""(porphyrin-containing compound metabolic process)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|interpro:IPR038071|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0006784""(heme A biosynthetic process)|go:""GO:0006785""(heme B biosynthetic process)|go:""GO:0006787""(porphyrin-containing compound catabolic process)|go:""GO:0048034""(heme O biosynthetic process)|interpro:IPR000257(""Uroporphyrinogen decarboxylase (URO-D)"")|interpro:IPR006361(Uroporphyrinogen decarboxylase HemE)|mint:P06132|rcsb pdb:1JPH|rcsb pdb:1JPI|rcsb pdb:1JPK|rcsb pdb:1R3Q|rcsb pdb:1R3R|rcsb pdb:1R3S|rcsb pdb:1R3T|rcsb pdb:1R3V|rcsb pdb:1R3W|rcsb pdb:1R3Y|rcsb pdb:1URO|rcsb pdb:2Q6Z|rcsb pdb:2Q71|rcsb pdb:3GVQ|rcsb pdb:3GVR|rcsb pdb:3GVV|rcsb pdb:3GVW|rcsb pdb:3GW0|rcsb pdb:3GW3|reactome:R-HSA-189451|refseq:NP_000365.3|panther:PTHR21091(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:z7CP0Z1yVLMjDRwXMe4ENFXu1aM9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9BTT0	intact:EBI-27055528	intact:EBI-2685059|uniprotkb:Q5TB18|uniprotkb:Q8N1S4|uniprotkb:Q8WWW9|uniprotkb:B4E0I6|uniprotkb:E9PEA6|uniprotkb:Q5TB20|ensembl:ENSP00000463154.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:an32e_human(display_long)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:ANP32E(gene name)|psi-mi:ANP32E(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001129950.1|refseq:NP_001129951.1|refseq:NP_112182.1|refseq:NP_001267488.1|refseq:NP_001267489.1|ensembl:ENSG00000143401.15(gene)|ensembl:ENST00000583931.6(transcript)|go:""GO:0000812""(Swr1 complex)|go:""GO:0005634""(nucleus)|go:""GO:0006325""(chromatin organization)|go:""GO:0019212""(phosphatase inhibitor activity)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0042393""(histone binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098895""(postsynaptic endosome membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140713""(histone chaperone activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR045081|mint:Q9BTT0|rcsb pdb:4CAY|rcsb pdb:4NFT|panther:PTHR11375(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:byeFwwxqINXwewx0Gx/QXSyes8g9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q01469	intact:EBI-27055528	intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258.6	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001435.1|go:""GO:0005654""(nucleoplasm)|ensembl:ENSG00000164687.11(gene)|ensembl:ENST00000297258.11(transcript)|go:""GO:0001972""(retinoic acid binding)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005504""(fatty acid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006656""(phosphatidylcholine biosynthetic process)|go:""GO:0008289""(lipid binding)|go:""GO:0008544""(epidermis development)|go:""GO:0010829""(negative regulation of D-glucose transmembrane transport)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015908""(fatty acid transport)|go:""GO:0015909""(long-chain fatty acid transport)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031392""(regulation of prostaglandin biosynthetic process)|go:""GO:0035360""(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0045202""(synapse)|go:""GO:0051930""(regulation of sensory perception of pain)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098921""(retrograde trans-synaptic signaling by endocannabinoid)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0099178""(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1990379""(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|rcsb pdb:7FWI|rcsb pdb:7FXD|rcsb pdb:7FY0|rcsb pdb:7FYD|rcsb pdb:7G01|rcsb pdb:7G04|rcsb pdb:7G0B|rcsb pdb:7G0E|rcsb pdb:7G1Q|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695|reactome:R-HSA-9725554|panther:PTHR11955(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O94822	intact:EBI-27055528	intact:EBI-1044684|uniprotkb:A6NL41|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|ensembl:ENSP00000354977.4|ensembl:ENSP00000373846.3|ensembl:ENSP00000517021.1|ensembl:ENSP00000517022.1|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:J3KPL4|intact:EBI-11051127	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000198862.14(gene)|go:""GO:0051865""(protein autoubiquitination)|ensembl:ENSG00000291534.1(gene)|ensembl:ENST00000361371.10(transcript)|ensembl:ENST00000389194.7(transcript)|ensembl:ENST00000707893.1(transcript)|ensembl:ENST00000707894.1(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:1990112""(RQC complex)|go:""GO:1990116""(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|interpro:IPR054476|interpro:IPR054477|interpro:IPR054478|mint:O94822|rcsb pdb:3J92|reactome:R-HSA-983168|refseq:NP_001307695.1|refseq:NP_056380.2|panther:PTHR12389(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q15773	intact:EBI-27055528	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630.5|ensembl:ENSP00000403941.1|ensembl:ENSP00000446317.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_005430.1|ensembl:ENSG00000089693.11(gene)|ensembl:ENST00000203630.10(transcript)|ensembl:ENST00000435120.5(transcript)|ensembl:ENST00000539187.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016020""(membrane)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR019376|mint:Q15773|panther:PTHR13105(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8NF91	intact:EBI-27055528	intact:EBI-928867|uniprotkb:E7EQI5|uniprotkb:Q5JV22|uniprotkb:O94890|uniprotkb:Q5JV19|uniprotkb:Q8N9P7|uniprotkb:Q8TCP1|uniprotkb:Q8WWW6|uniprotkb:Q8WWW7|uniprotkb:Q8WXF6|uniprotkb:Q96N17|uniprotkb:Q9C0A7|uniprotkb:Q9H525|uniprotkb:Q9H526|uniprotkb:Q9NS36|uniprotkb:Q9NU50|uniprotkb:Q9UJ06|uniprotkb:Q9UJ07|uniprotkb:Q9ULF8|ensembl:ENSP00000356224.5|uniprotkb:B3W695|uniprotkb:H0Y4C0|uniprotkb:Q3ZCV0	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:syne1_human(display_long)|uniprotkb:SYNE1(gene name)|psi-mi:SYNE1(display_short)|uniprotkb:KIAA0796(gene name synonym)|uniprotkb:KIAA1262(gene name synonym)|uniprotkb:KIAA1756(gene name synonym)|uniprotkb:MYNE1(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 1(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 1(gene name synonym)|uniprotkb:Myocyte nuclear envelope protein 1(gene name synonym)|uniprotkb:C6orf98(gene name synonym)|uniprotkb:Enaptin(gene name synonym)|uniprotkb:KASH domain-containing protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000131018.25(gene)|ensembl:ENST00000367255.10(transcript)|go:""GO:0000932""(P-body)|go:""GO:0002053""(positive regulation of mesenchymal cell proliferation)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006997""(nucleus organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007283""(spermatogenesis)|go:""GO:0009416""(response to light stimulus)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030017""(sarcomere)|go:""GO:0030496""(midbody)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034993""(meiotic nuclear membrane microtubule tethering complex)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044327""(dendritic spine head)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048814""(regulation of dendrite morphogenesis)|go:""GO:0051015""(actin filament binding)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0061886""(negative regulation of mini excitatory postsynaptic potential)|go:""GO:0090292""(nuclear matrix anchoring at nuclear membrane)|go:""GO:0098843""(postsynaptic endocytic zone)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:0140444""(cytoskeleton-nuclear membrane anchor activity)|go:""GO:1903353""(regulation of nucleus organization)|go:""GO:2001054""(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR036872|interpro:IPR047290|interpro:IPR047291|mint:Q8NF91|rcsb pdb:4DXR|rcsb pdb:6R15|rcsb pdb:6XF2|reactome:R-HSA-1221632|refseq:NP_001334631.1|refseq:NP_149062.1|refseq:NP_892006.3|efo:""Orphanet:319332""|efo:""Orphanet:88644""|efo:""Orphanet:98853""|panther:PTHR14514(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:6nWMBf60nycHwNcMMQJL5JqanEc9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9UI12	intact:EBI-27055528	intact:EBI-724719|uniprotkb:Q6PK44|uniprotkb:Q9H3E3|uniprotkb:Q9Y300|uniprotkb:B3KMR0|ensembl:ENSP00000352522.2|ensembl:ENSP00000379995.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:vath_human(display_long)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 50/57 kDa subunits(gene name synonym)|uniprotkb:Vacuolar proton pump subunit SFD(gene name synonym)|uniprotkb:Protein VMA13 homolog(gene name synonym)|uniprotkb:Nef-binding protein 1(gene name synonym)|uniprotkb:ATP6V1H(gene name)|psi-mi:ATP6V1H(display_short)|uniprotkb:CGI-11(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_057025.2|refseq:NP_998784.1|refseq:NP_998785.1|refseq:XP_006716518.1|ensembl:ENSG00000047249.18(gene)|ensembl:ENST00000359530.7(transcript)|ensembl:ENST00000396774.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000221""(vacuolar proton-transporting V-type ATPase, V1 domain)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0051452""(intracellular pH reduction)|go:""GO:0061795""(Golgi lumen acidification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0098850""(extrinsic component of synaptic vesicle membrane)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|mint:Q9UI12|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7FDA|rcsb pdb:7FDB|rcsb pdb:7FDC|rcsb pdb:7U4T|rcsb pdb:7UNF|reactome:R-HSA-1222556|reactome:R-HSA-167590|reactome:R-HSA-182218|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9636467|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-9857377|panther:PTHR10698(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:n2fyA8m4qnlSmS3R1xBBE3RRV9A9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q13616	intact:EBI-27055528	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804.3|ensembl:ENSP00000387160.1|ensembl:ENSP00000473318.1|ensembl:ENSP00000499255.1|ensembl:ENSP00000499277.1|ensembl:ENSP00000499398.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_003583.2|refseq:XP_005250117.1|ensembl:ENSG00000055130.18(gene)|ensembl:ENST00000325222.9(transcript)|ensembl:ENST00000409469.5(transcript)|ensembl:ENST00000602748.5(transcript)|ensembl:ENST00000662716.1(transcript)|ensembl:ENST00000663044.1(transcript)|ensembl:ENST00000665936.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019005""(SCF ubiquitin ligase complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031146""(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0031461""(cullin-RING ubiquitin ligase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0160072""(ubiquitin ligase complex scaffold activity)|go:""GO:1990452""(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|interpro:IPR045093|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|rcsb pdb:7Z8R|rcsb pdb:7Z8T|rcsb pdb:7Z8V|rcsb pdb:7ZBW|rcsb pdb:7ZBZ|rcsb pdb:8CAF|rcsb pdb:8CDJ|rcsb pdb:8CDK|rcsb pdb:8OR0|rcsb pdb:8OR2|rcsb pdb:8OR3|rcsb pdb:8OR4|rcsb pdb:9JKB|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-9725371|reactome:R-HSA-9762114|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|dip:DIP-17013N|panther:PTHR11932(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:S4R3E9	intact:EBI-27055528	intact:EBI-27055574|ensembl:ENSP00000474249.1|ensembl:ENSP00000494020.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:s4r3e9_human(display_long)|uniprotkb:Neddylin(gene name synonym)|uniprotkb:NEDD8-MDP1(gene name)|psi-mi:NEDD8-MDP1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	ensembl:ENSG00000255526.6(gene)|ensembl:ENSG00000285425.1(gene)|ensembl:ENST00000605847.5(transcript)|ensembl:ENST00000642609.1(transcript)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|interpro:IPR050158	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:ZPdm9CNEFoVn2RFmJkbN3w1Htv09606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8NEZ5	intact:EBI-27055528	intact:EBI-2510137|uniprotkb:Q9H824|uniprotkb:Q6PIL5|uniprotkb:Q9UKC0|uniprotkb:Q0D2P8|uniprotkb:Q8IXW3|ensembl:ENSP00000307833.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:fbx22_human(display_long)|uniprotkb:FBXO22(gene name)|psi-mi:FBXO22(display_short)|uniprotkb:FBX22(gene name synonym)|uniprotkb:F-box protein FBX22p44(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_011519749.1|refseq:NP_036302.1|refseq:NP_671717.1|ensembl:ENSG00000167196.14(gene)|ensembl:ENST00000308275.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0030018""(Z disc)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0048742""(regulation of skeletal muscle fiber development)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR019494|interpro:IPR036047|mint:Q8NEZ5|reactome:R-HSA-8951664|reactome:R-HSA-983168|panther:PTHR14939(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:hOnBb3SK/OM+oGU8RdxmUb8MVDE9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P62308	intact:EBI-27055528	intact:EBI-624585|uniprotkb:Q15357|uniprotkb:Q6IB86|intact:EBI-1056206|uniprotkb:D6W5G6|ensembl:ENSP00000272348.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ruxg_human(display_long)|uniprotkb:SNRPG(gene name)|psi-mi:SNRPG(display_short)|uniprotkb:PBSCG(gene name synonym)|uniprotkb:Sm protein G(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_003087.1|ensembl:ENSG00000143977.14(gene)|ensembl:ENST00000272348.7(transcript)|go:""GO:0000245""(spliceosomal complex assembly)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005682""(U5 snRNP)|go:""GO:0005683""(U7 snRNP)|go:""GO:0005684""(U2-type spliceosomal complex)|go:""GO:0005685""(U1 snRNP)|go:""GO:0005686""(U2 snRNP)|go:""GO:0005687""(U4 snRNP)|go:""GO:0005689""(U12-type spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0008380""(RNA splicing)|go:""GO:0030532""(small nuclear ribonucleoprotein complex)|go:""GO:0034709""(methylosome)|go:""GO:0034719""(SMN-Sm protein complex)|go:""GO:0036261""(7-methylguanosine cap hypermethylation)|go:""GO:0043186""(P granule)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0071004""(U2-type prespliceosome)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071011""(precatalytic spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0097526""(spliceosomal tri-snRNP complex)|go:""GO:1903241""(U2-type prespliceosome assembly)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|interpro:IPR047575|mint:P62308|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|rcsb pdb:7EVO|rcsb pdb:7QTT|rcsb pdb:7VPX|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8Q7V|rcsb pdb:8H6L|rcsb pdb:8HK1|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8Q7Q|rcsb pdb:8Q7W|rcsb pdb:8Q7X|rcsb pdb:8Q91|rcsb pdb:8QO9|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RC0|rcsb pdb:8RM5|rcsb pdb:8RO2|rcsb pdb:8Y6O|rcsb pdb:8Y7E|rcsb pdb:9FMD|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-9754678|dip:DIP-34627N|panther:PTHR10553(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:bwbnMaq7QstuUpgUyJtFqzF5J/I9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q04323	intact:EBI-27055528	intact:EBI-1058647|intact:EBI-25600858|uniprotkb:Q9BV93|uniprotkb:Q9BVV5|intact:EBI-1993649|ensembl:ENSP00000303991.5|intact:EBI-25624438	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ubxn1_human(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001273006.1|refseq:NP_001273007.1|refseq:NP_056937.2|refseq:XP_005274090.1|ensembl:ENSG00000162191.14(gene)|ensembl:ENST00000301935.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0034098""(VCP-NPL4-UFD1 AAA ATPase complex)|go:""GO:0036435""(K48-linked polyubiquitin modification-dependent protein binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051117""(ATPase binding)|go:""GO:0071796""(K6-linked polyubiquitin modification-dependent protein binding)|go:""GO:1903094""(negative regulation of protein K48-linked deubiquitination)|go:""GO:1904293""(negative regulation of ERAD pathway)|go:""GO:1904855""(proteasome regulatory particle binding)|go:""GO:2000157""(negative regulation of ubiquitin-specific protease activity)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR041923|mint:Q04323|reactome:R-HSA-532668|reactome:R-HSA-5693565|refseq:XP_016873363.1|dip:DIP-29467N|panther:PTHR46340(orthology-group)"	-	-	crc64:E4E0C8BBAC93F2BB	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:KdHMRM9FSd6VT6MvJTxzdjARlRw9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y679	intact:EBI-27055528	intact:EBI-1058701|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8|ensembl:ENSP00000366748.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_853553.1|ensembl:ENSG00000115307.17(gene)|ensembl:ENST00000377526.4(transcript)|go:""GO:0005776""(autophagosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034389""(lipid droplet organization)|go:""GO:0036503""(ERAD pathway)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140042""(lipid droplet formation)|go:""GO:1990044""(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR048056|mint:Q9Y679|rcsb pdb:2EKF|rcsb pdb:7LEW|panther:PTHR15486(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q13526	intact:EBI-27055528	intact:EBI-714158|uniprotkb:Q53X75|uniprotkb:A8K4V9|ensembl:ENSP00000247970.5|ensembl:ENSP00000466962.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pin1_human(display_long)|uniprotkb:Rotamase Pin1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)|uniprotkb:PIN1(gene name)|psi-mi:PIN1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_006212.1|ensembl:ENSG00000127445.14(gene)|ensembl:ENST00000247970.9(transcript)|ensembl:ENST00000588695.5(transcript)|go:""GO:0000413""(protein peptidyl-prolyl isomerization)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016607""(nuclear speck)|go:""GO:0016859""(cis-trans isomerase activity)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030496""(midbody)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031434""(mitogen-activated protein kinase kinase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048156""(tau protein binding)|go:""GO:0050808""(synapse organization)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0050816""(phosphothreonine residue binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0060392""(negative regulation of SMAD protein signal transduction)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|go:""GO:1900180""(regulation of protein localization to nucleus)|go:""GO:1902430""(negative regulation of amyloid-beta formation)|go:""GO:1990757""(ubiquitin ligase activator activity)|go:""GO:2000146""(negative regulation of cell motility)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR023058|interpro:IPR036020|interpro:IPR046357|interpro:IPR051370|mint:Q13526|rcsb pdb:1F8A|rcsb pdb:1I6C|rcsb pdb:1I8G|rcsb pdb:1I8H|rcsb pdb:1NMV|rcsb pdb:1NMW|rcsb pdb:1PIN|rcsb pdb:1ZCN|rcsb pdb:2F21|rcsb pdb:2ITK|rcsb pdb:2KBU|rcsb pdb:2KCF|rcsb pdb:2LB3|rcsb pdb:2M8I|rcsb pdb:2M8J|rcsb pdb:2M9E|rcsb pdb:2M9F|rcsb pdb:2M9I|rcsb pdb:2M9J|rcsb pdb:2N1O|rcsb pdb:2Q5A|rcsb pdb:2RUC|rcsb pdb:2RUD|rcsb pdb:2RUQ|rcsb pdb:2RUR|rcsb pdb:2XP3|rcsb pdb:2XP4|rcsb pdb:2XP5|rcsb pdb:2XP6|rcsb pdb:2XP7|rcsb pdb:2XP8|rcsb pdb:2XP9|rcsb pdb:2XPA|rcsb pdb:2XPB|rcsb pdb:2ZQS|rcsb pdb:2ZQT|rcsb pdb:2ZQU|rcsb pdb:2ZQV|rcsb pdb:2ZR4|rcsb pdb:2ZR5|rcsb pdb:2ZR6|rcsb pdb:3I6C|rcsb pdb:3IK8|rcsb pdb:3IKD|rcsb pdb:3IKG|rcsb pdb:3JYJ|rcsb pdb:3KAB|rcsb pdb:3KAC|rcsb pdb:3KAD|rcsb pdb:3KAF|rcsb pdb:3KAG|rcsb pdb:3KAH|rcsb pdb:3KAI|rcsb pdb:3KCE|rcsb pdb:3NTP|rcsb pdb:3ODK|rcsb pdb:3OOB|rcsb pdb:3TC5|rcsb pdb:3TCZ|rcsb pdb:3TDB|rcsb pdb:3WH0|rcsb pdb:4GWT|rcsb pdb:4GWV|rcsb pdb:4QIB|rcsb pdb:4TNS|rcsb pdb:4TYO|rcsb pdb:4U84|rcsb pdb:4U85|rcsb pdb:4U86|rcsb pdb:5B3W|rcsb pdb:5B3X|rcsb pdb:5B3Y|rcsb pdb:5B3Z|rcsb pdb:5BMY|rcsb pdb:5GPH|rcsb pdb:5UY9|rcsb pdb:5VTI|rcsb pdb:5VTJ|rcsb pdb:5VTK|rcsb pdb:6DUN|rcsb pdb:6O33|rcsb pdb:6O34|rcsb pdb:6SVC|rcsb pdb:6SVE|rcsb pdb:6SVH|rcsb pdb:6VAJ|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7EFJ|rcsb pdb:7EFX|rcsb pdb:7EKV|rcsb pdb:7F0M|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJA|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7OQ9|rcsb pdb:7OQA|rcsb pdb:7SA5|rcsb pdb:7SUQ|rcsb pdb:7SUR|rcsb pdb:8C2G|rcsb pdb:8C3C|rcsb pdb:8SG2|rcsb pdb:9INR|rcsb pdb:9IT1|reactome:R-HSA-1169408|reactome:R-HSA-5668599|reactome:R-HSA-6804756|reactome:R-HSA-6811555|reactome:R-HSA-936440|dip:DIP-29306N|panther:PTHR10657(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:FICkSpcBgvSDFW4iY1Etik85xNo9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O95372	intact:EBI-27055528	intact:EBI-715999|uniprotkb:Q7Z4Z2|ensembl:ENSP00000363638.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:lypa2_human(display_long)|uniprotkb:Lysophospholipase II(gene name synonym)|uniprotkb:LYPLA2(gene name)|psi-mi:LYPLA2(display_short)|uniprotkb:APT2(gene name synonym)|uniprotkb:Palmitoyl-protein hydrolase(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_009191.1|ensembl:ENSG00000011009.12(gene)|ensembl:ENST00000374514.8(transcript)|go:""GO:0002084""(protein depalmitoylation)|go:""GO:0004622""(lysophospholipase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005795""(Golgi stack)|go:""GO:0005829""(cytosol)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0007411""(axon guidance)|go:""GO:0008474""(""palmitoyl-(protein) hydrolase activity"")|go:""GO:0045296""(cadherin binding)|go:""GO:0046464""(acylglycerol catabolic process)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905344""(prostaglandin catabolic process)|interpro:IPR003140(Phospholipase/carboxylesterase)|interpro:IPR029058|interpro:IPR050565|mint:O95372|rcsb pdb:5SYN|rcsb pdb:6BJE|reactome:R-HSA-373760|panther:PTHR10655(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:yJ0IGnOIc6UvuzuLdZb8WzlN9aY9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y4X5	intact:EBI-27055528	intact:EBI-2514233|uniprotkb:Q9UEN0|uniprotkb:Q9H3T6|uniprotkb:O76026|uniprotkb:Q9UP39|uniprotkb:B2R6U3|ensembl:ENSP00000369217.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ari1_human(display_long)|uniprotkb:Protein ariadne-1 homolog(gene name synonym)|uniprotkb:ARIH1(gene name)|psi-mi:ARIH1(display_short)|uniprotkb:ARI(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:UBCH7BP(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-binding protein 1(gene name synonym)|uniprotkb:UbcH7-binding protein(gene name synonym)|uniprotkb:UbcM4-interacting protein(gene name synonym)|uniprotkb:HHARI(gene name synonym)|uniprotkb:H7-AP2(gene name synonym)|uniprotkb:Monocyte protein 6(gene name synonym)|uniprotkb:HUSSY-27(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000166233.15(gene)|ensembl:ENST00000379887.9(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0015030""(Cajal body)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0019787""(ubiquitin-like protein transferase activity)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0039585""(PKR/eIFalpha signaling)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0097413""(Lewy body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|interpro:IPR031127|interpro:IPR044066|interpro:IPR045840|interpro:IPR048962|mint:Q9Y4X5|rcsb pdb:1WD2|rcsb pdb:2M9Y|rcsb pdb:4KBL|rcsb pdb:4KC9|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5S|reactome:R-HSA-1169408|reactome:R-HSA-9833110|reactome:R-HSA-9833482|refseq:NP_005735.2|dip:DIP-53626N|panther:PTHR11685(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:4au2wa0c7NccURO3aKdmKN0U3PE9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q5JVF3	intact:EBI-27055528	intact:EBI-1051701|uniprotkb:A6NK09|uniprotkb:Q3ZCX1|uniprotkb:Q5TC57|uniprotkb:Q5TC58|uniprotkb:Q9H7K1|uniprotkb:Q9HBZ7|uniprotkb:Q9NUK6|uniprotkb:Q9NVY1|uniprotkb:Q9NW44|uniprotkb:Q9NWH3|ensembl:ENSP00000337405.4|ensembl:ENSP00000364626.1|ensembl:ENSP00000364628.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pcid2_human(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short)|uniprotkb:HT004(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001120674.1|refseq:NP_001120675.1|refseq:NP_060856.2|refseq:NP_001245142.1|refseq:NP_001307584.1|refseq:NP_001307585.1|refseq:NP_001307586.1|refseq:NP_001307589.1|refseq:XP_016876153.1|dip:DIP-50497N|ensembl:ENSG00000126226.22(gene)|ensembl:ENST00000337344.9(transcript)|ensembl:ENST00000375477.5(transcript)|ensembl:ENST00000375479.6(transcript)|go:""GO:0000973""(post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0015031""(protein transport)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0044615""(nuclear pore nuclear basket)|go:""GO:0045579""(positive regulation of B cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048536""(spleen development)|go:""GO:0060633""(negative regulation of transcription initiation by RNA polymerase II)|go:""GO:0070390""(transcription export complex 2)|go:""GO:0070828""(heterochromatin organization)|go:""GO:0090267""(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:""GO:1905457""(negative regulation of lymphoid progenitor cell differentiation)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR045114|mint:Q5JVF3|rcsb pdb:3T5X|panther:PTHR12732(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q92615	intact:EBI-27055528	intact:EBI-1052558|uniprotkb:Q5T3R3|uniprotkb:Q5T3R4|uniprotkb:Q5T3R5|uniprotkb:Q68CY4|uniprotkb:A7MD20|intact:EBI-28969094|ensembl:ENSP00000326128.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:lar4b_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:LARP4B(gene name)|psi-mi:LARP4B(display_short)|uniprotkb:LARP5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym)|uniprotkb:KIAA0217(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_055970.1|ensembl:ENSG00000107929.16(gene)|ensembl:ENST00000316157.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0045727""(positive regulation of translation)|go:""GO:1905870""(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034900|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:Q92615|rcsb pdb:3PTH|panther:PTHR22792(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:tVFpPu0vhCgdRt0lowfi5GzA8Do9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q92879	intact:EBI-27055528	intact:EBI-713032|uniprotkb:Q4LE52|uniprotkb:Q9NP83|uniprotkb:Q9NR06|uniprotkb:D3DQS0|uniprotkb:B4E2U5|uniprotkb:F8W940|ensembl:ENSP00000351409.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:celf1_human(display_long)|uniprotkb:Bruno-like protein 2(gene name synonym)|uniprotkb:RNA-binding protein BRUNOL-2(gene name synonym)|uniprotkb:CUG triplet repeat RNA-binding protein 1(gene name synonym)|uniprotkb:Deadenylation factor CUG-BP(gene name synonym)|uniprotkb:50 kDa nuclear polyadenylated RNA-binding protein(gene name synonym)|uniprotkb:Embryo deadenylation element-binding protein homolog(gene name synonym)|uniprotkb:CELF1(gene name)|psi-mi:CELF1(display_short)|uniprotkb:BRUNOL2(gene name synonym)|uniprotkb:CUGBP(gene name synonym)|uniprotkb:NAB50(gene name synonym)|uniprotkb:CUGBP1(gene name synonym)|uniprotkb:CUG-BP- and ETR-3-like factor 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000149187.19(gene)|ensembl:ENST00000358597.7(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000900""(mRNA regulatory element binding translation repressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006376""(mRNA splice site recognition)|go:""GO:0006397""(mRNA processing)|go:""GO:0007281""(germ cell development)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009792""(embryo development ending in birth or egg hatching)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016441""(post-transcriptional gene silencing)|go:""GO:0035194""(regulatory ncRNA-mediated post-transcriptional gene silencing)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0042835""(BRE binding)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0061157""(mRNA destabilization)|go:""GO:0097356""(perinucleolar compartment)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034196|interpro:IPR034198|interpro:IPR034199|interpro:IPR035979|mint:Q92879|rcsb pdb:2CPZ|rcsb pdb:2DHS|rcsb pdb:2RQ4|rcsb pdb:2RQC|rcsb pdb:3NMR|rcsb pdb:3NNA|rcsb pdb:3NNC|rcsb pdb:3NNH|refseq:XP_011518161.1|refseq:NP_001020767.1|refseq:NP_001166110.1|refseq:NP_001166111.1|refseq:NP_006551.1|refseq:NP_941989.1|refseq:XP_016872613.1|refseq:XP_016872614.1|refseq:XP_016872615.1|refseq:XP_016872616.1|refseq:XP_016872617.1|refseq:XP_016872618.1|refseq:XP_016872619.1|refseq:XP_016872620.1|refseq:XP_016872621.1|refseq:XP_016872622.1|refseq:XP_016872623.1|refseq:XP_016872624.1|panther:PTHR24012(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:MUTvmDd0BGmmliUR0FEiHnZq0v49606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9NWB6	intact:EBI-27055528	intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_060481.3|ensembl:ENSG00000134884.15(gene)|ensembl:ENST00000400198.8(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0045296""(cadherin binding)|interpro:IPR033371|mint:Q9NWB6|panther:PTHR31711(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9H4A6	intact:EBI-27055528	intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070.6	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_071413.1|ensembl:ENSG00000113384.14(gene)|ensembl:ENST00000265070.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0009101""(glycoprotein biosynthetic process)|go:""GO:0009306""(protein secretion)|go:""GO:0010467""(gene expression)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0016477""(cell migration)|go:""GO:0019899""(enzyme binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0031985""(Golgi cisterna)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045053""(protein retention in Golgi apparatus)|go:""GO:0048194""(Golgi vesicle budding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0060352""(cell adhesion molecule production)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0072752""(cellular response to rapamycin)|go:""GO:0090161""(Golgi ribbon formation)|go:""GO:0090164""(asymmetric Golgi ribbon formation)|go:""GO:0140312""(cargo adaptor activity)|go:""GO:0140450""(protein targeting to Golgi apparatus)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1|panther:PTHR12704(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9UBD5	intact:EBI-27055528	intact:EBI-374916|uniprotkb:A2A2T5|uniprotkb:Q13565|uniprotkb:Q53GY6|uniprotkb:Q5T159|uniprotkb:Q6IUY7|uniprotkb:Q86TN5|uniprotkb:Q9UG44|uniprotkb:Q9UNT6|uniprotkb:B4E025|ensembl:ENSP00000376586.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:orc3_human(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:LATHEO(gene name synonym)|uniprotkb:Origin recognition complex subunit Latheo(gene name synonym)|uniprotkb:ORC3L(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR12748(orthology-group)|refseq:NP_036513.2|refseq:NP_862820.1|refseq:NP_001184188.1|ensembl:ENSG00000135336.17(gene)|ensembl:ENST00000392844.8(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0000808""(origin recognition complex)|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005656""(nuclear pre-replicative complex)|go:""GO:0005664""(nuclear origin of replication recognition complex)|go:""GO:0006260""(DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016604""(nuclear body)|go:""GO:0031261""(DNA replication preinitiation complex)|go:""GO:0061351""(neural precursor cell proliferation)|interpro:IPR020795|interpro:IPR040855|interpro:IPR045663|interpro:IPR045667|mint:Q9UBD5|rcsb pdb:5UJ8|rcsb pdb:5UJM|rcsb pdb:7CTE|rcsb pdb:7CTF|rcsb pdb:7CTG|rcsb pdb:7JPO|rcsb pdb:7JPP|rcsb pdb:7JPQ|rcsb pdb:7JPR|rcsb pdb:7JPS|rcsb pdb:8S0C|rcsb pdb:8S0D|rcsb pdb:8S0E|rcsb pdb:8S0F|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-68616|reactome:R-HSA-68689|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|dip:DIP-31735N"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:ldvEZZ/fRPP3yHQJJIhf0zxYeLM9606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9BUQ8	intact:EBI-27055528	intact:EBI-540096|uniprotkb:B2R600|uniprotkb:O43188|intact:EBI-2557638|uniprotkb:B4DH15|ensembl:ENSP00000310723.2|intact:EBI-21357842	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ddx23_human(display_long)|uniprotkb:DEAD box protein 23(gene name synonym)|uniprotkb:100 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:U5-100kD(gene name synonym)|uniprotkb:PRP28 homolog(gene name synonym)|uniprotkb:DDX23(gene name)|psi-mi:DDX23(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055586|imex:IM-29147-21	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004809.2|ensembl:ENSG00000174243.11(gene)|ensembl:ENST00000308025.8(transcript)|go:""GO:0000354""(cis assembly of pre-catalytic spliceosome)|go:""GO:0000375""(RNA splicing, via transesterification reactions)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000785""(chromatin)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005682""(U5 snRNP)|go:""GO:0005730""(nucleolus)|go:""GO:0008380""(RNA splicing)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0062176""(R-loop processing)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9BUQ8|rcsb pdb:3JCR|rcsb pdb:4NHO|rcsb pdb:6AH0|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8Q7W|rcsb pdb:8Q7X|rcsb pdb:8Q91|rcsb pdb:8QOZ|rcsb pdb:8QP8|rcsb pdb:8QP9|rcsb pdb:8QPA|rcsb pdb:8QPB|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RC0|rcsb pdb:8RM5|rcsb pdb:8Y6O|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-34974N|panther:PTHR47958(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/27	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:tEDp48akFaCjRBBXB4jtyrAsLQ89606	intact-crc:CFDBE407A69C9CED	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P35580	intact:EBI-27055664	intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45|ensembl:ENSP00000269243.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|interpro:IPR002928(Myosin tail)|ensembl:ENSG00000133026.14(gene)|ensembl:ENST00000269243.8(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0016459""(myosin complex)|go:""GO:0016460""(myosin II complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030048""(actin filament-based movement)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|go:""GO:0030496""(midbody)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032982""(myosin filament)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0042641""(actomyosin)|go:""GO:0043531""(ADP binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097513""(myosin II filament)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N|panther:PTHR45615(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P60660	intact:EBI-27055664	intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9|ensembl:ENSP00000446955.2|ensembl:ENSP00000448101.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_066299.2|refseq:NP_524147.2|ensembl:ENSG00000092841.19(gene)|ensembl:ENST00000548293.5(transcript)|ensembl:ENST00000550697.6(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0006936""(muscle contraction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0016020""(membrane)|go:""GO:0016459""(myosin complex)|go:""GO:0016460""(myosin II complex)|go:""GO:0016461""(unconventional myosin complex)|go:""GO:0030049""(muscle filament sliding)|go:""GO:0031982""(vesicle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR050230|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|panther:PTHR23048(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O14950	intact:EBI-27055664	intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500.5|ensembl:ENSP00000383037.5|ensembl:ENSP00000463559.1|ensembl:ENSP00000464464.1|ensembl:ENSP00000496809.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680.14(gene)|ensembl:ENST00000237500.10(transcript)|ensembl:ENST00000400175.9(transcript)|ensembl:ENST00000581193.5(transcript)|ensembl:ENST00000584539.1(transcript)|ensembl:ENST00000648965.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016460""(myosin II complex)|go:""GO:0030016""(myofibril)|go:""GO:0030018""(Z disc)|go:""GO:0032036""(myosin heavy chain binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|interpro:IPR050403|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|panther:PTHR23049(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P35579	intact:EBI-27055664	intact:EBI-350338|uniprotkb:O60805|uniprotkb:Q86T83|intact:EBI-1054343|intact:EBI-25631636|uniprotkb:A8K6E4|uniprotkb:Q60FE2|ensembl:ENSP00000216181.6	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"efo:""Orphanet:182050""|efo:""Orphanet:477742""|efo:""Orphanet:90635""|ensembl:ENSG00000100345.23(gene)|ensembl:ENST00000216181.11(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000212""(meiotic spindle organization)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0001931""(uropod)|go:""GO:0003723""(RNA binding)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005826""(actomyosin contractile ring)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016604""(nuclear body)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030220""(platelet formation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032418""(lysosome localization)|go:""GO:0032506""(cytokinetic process)|go:""GO:0032796""(uropod organization)|go:""GO:0032982""(myosin filament)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042641""(actomyosin)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043531""(ADP binding)|go:""GO:0043534""(blood vessel endothelial cell migration)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051015""(actin filament binding)|go:""GO:0051295""(establishment of meiotic spindle localization)|go:""GO:0060471""(cortical granule exocytosis)|go:""GO:0060473""(cortical granule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097513""(myosin II filament)|go:""GO:1903919""(negative regulation of actin filament severing)|go:""GO:1903923""(positive regulation of protein processing in phagocytic vesicle)|go:""GO:1905684""(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|reactome:R-HSA-9725370|refseq:NP_002464.1|refseq:XP_011528499.1|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|panther:PTHR45615(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P98175	intact:EBI-27055664	intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|ensembl:ENSP00000366829.3|uniprotkb:A0A0A0MR66	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"efo:""Orphanet:2886""|ensembl:ENSG00000182872.16(gene)|ensembl:ENST00000377604.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048025""(negative regulation of mRNA splicing, via spliceosome)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1905288""(vascular associated smooth muscle cell apoptotic process)|go:""GO:1905461""(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:""GO:1990874""(vascular associated smooth muscle cell proliferation)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_001191397.1|refseq:NP_005667.2|refseq:NP_690595.1|panther:PTHR13948(orthology-group)|ensembl:ENST00000329236.8|ensembl:ENSP00000328848.8|ensembl:ENST00000345781.10|ensembl:ENSP00000329659.6|ensembl:ENSP00000366829.3|ensembl:ENST00000628161.2|ensembl:ENSP00000486115.1"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P61026	intact:EBI-27055664	intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_057215.3|ensembl:ENSG00000084733.11(gene)|ensembl:ENST00000264710.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0007409""(axonogenesis)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0019003""(GDP binding)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0031489""(myosin V binding)|go:""GO:0032593""(insulin-responsive compartment)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045200""(establishment of neuroblast polarity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070382""(exocytic vesicle)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0097051""(establishment of protein localization to endoplasmic reticulum membrane)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0099503""(secretory vesicle)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:P61026|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P55884	intact:EBI-27055664	intact:EBI-366696|uniprotkb:Q2NL77|uniprotkb:Q9UMF9|uniprotkb:A4D208|intact:EBI-25643250|ensembl:ENSP00000354125.4|ensembl:ENSP00000380206.2	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:eif3b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:Prt1 homolog(gene name synonym)|uniprotkb:EIF3B(gene name)|psi-mi:EIF3B(display_short)|uniprotkb:EIF3S9(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"panther:PTHR14068(orthology-group)|refseq:NP_001032360.1|refseq:NP_003742.2|ensembl:ENSG00000106263.19(gene)|ensembl:ENST00000360876.9(transcript)|ensembl:ENST00000397011.2(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0045202""(synapse)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071541""(eukaryotic translation initiation factor 3 complex, eIF3m)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0075525""(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:P55884|rcsb pdb:2KRB|rcsb pdb:2NLW|rcsb pdb:5K1H|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8XXN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_011513901.1|refseq:XP_011513902.1|refseq:XP_016868241.1|dip:DIP-31113N"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:MxQFPvmuOcO/S+4NqzToozWr8K89606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q7L576	intact:EBI-27055664	intact:EBI-1048143|uniprotkb:Q14467|uniprotkb:Q5IED0|uniprotkb:Q6ZSX1|uniprotkb:Q9BSD9|uniprotkb:Q9BVC7|uniprotkb:A8K6D9|ensembl:ENSP00000478779.1|ensembl:ENSP00000481038.1|ensembl:ENSP00000499947.1|ensembl:ENSP00000500331.1	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:cyfp1_human(display_long)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)|uniprotkb:p140sra-1(gene name synonym)|uniprotkb:CYFIP1(gene name)|psi-mi:CYFIP1(display_short)|uniprotkb:KIAA0068(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001028200.1|refseq:NP_055423.1|refseq:NP_001274739.1|ensembl:ENSG00000273749.5(gene)|ensembl:ENSG00000288461.1(gene)|ensembl:ENST00000610365.4(transcript)|ensembl:ENST00000617928.5(transcript)|ensembl:ENST00000671714.1(transcript)|ensembl:ENST00000672091.1(transcript)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001726""(ruffle)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006417""(regulation of translation)|go:""GO:0007411""(axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0030027""(lamellipodium)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030371""(translation repressor activity)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0031209""(SCAR complex)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031529""(ruffle organization)|go:""GO:0031641""(regulation of myelination)|go:""GO:0032433""(filopodium tip)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043195""(terminal bouton)|go:""GO:0043197""(dendritic spine)|go:""GO:0044294""(dendritic growth cone)|go:""GO:0044295""(axonal growth cone)|go:""GO:0045202""(synapse)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048675""(axon extension)|go:""GO:0050890""(cognition)|go:""GO:0051015""(actin filament binding)|go:""GO:0051388""(positive regulation of neurotrophin TRK receptor signaling pathway)|go:""GO:0051602""(response to electrical stimulus)|go:""GO:0060076""(excitatory synapse)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090724""(central region of growth cone)|go:""GO:0090725""(peripheral region of growth cone)|go:""GO:0097484""(dendrite extension)|go:""GO:0099563""(modification of synaptic structure)|go:""GO:0099578""(regulation of translation at postsynapse, modulating synaptic transmission)|go:""GO:1900006""(positive regulation of dendrite development)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1903422""(negative regulation of synaptic vesicle recycling)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:2000601""(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7L576|rcsb pdb:3P8C|rcsb pdb:4N78|rcsb pdb:7USC|rcsb pdb:7USD|rcsb pdb:7USE|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001311049.1|refseq:NP_001311052.1|dip:DIP-38873N|panther:PTHR12195(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:cEF+RA9JRXz8Mbsl/s89Up2ONRc9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q99623	intact:EBI-27055664	intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875.1|uniprotkb:B4DP75	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001138303.1|refseq:NP_001254629.1|ensembl:ENSG00000215021.10(gene)|ensembl:ENST00000535923.6(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0009986""(cell surface)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030424""(axon)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0031536""(positive regulation of exit from mitosis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033147""(negative regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0033218""(amide binding)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0033600""(negative regulation of mammary gland epithelial cell proliferation)|go:""GO:0035632""(mitochondrial prohibitin complex)|go:""GO:0039529""(RIG-I signaling pathway)|go:""GO:0042113""(B cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046625""(sphingolipid binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050821""(protein stabilization)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060744""(mammary gland branching involved in thelarche)|go:""GO:0060749""(mammary gland alveolus development)|go:""GO:0060762""(regulation of branching involved in mammary gland duct morphogenesis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071944""(cell periphery)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1900208""(regulation of cardiolipin metabolic process)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902808""(positive regulation of cell cycle G1/S phase transition)|go:""GO:1904959""(regulation of cytochrome-c oxidase activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|rcsb pdb:8J4I|reactome:R-HSA-8949664|reactome:R-HSA-9840373|panther:PTHR23222(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:h4pib54mBeQgOKCe/hib58LM26w9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:Q14152	intact:EBI-27055664	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|uniprotkb:B4DYS1|uniprotkb:F5H335|ensembl:ENSP00000358140.3	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"panther:PTHR14005(orthology-group)|refseq:NP_003741.1|ensembl:ENSG00000107581.14(gene)|ensembl:ENST00000369144.8(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0002188""(translation reinitiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0043614""(multi-eIF complex)|go:""GO:0071540""(eukaryotic translation initiation factor 3 complex, eIF3e)|go:""GO:0071541""(eukaryotic translation initiation factor 3 complex, eIF3m)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0075525""(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|interpro:IPR054711|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8RG0|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P63010	intact:EBI-27055664	intact:EBI-432924|ensembl:ENSP00000482315.1|uniprotkb:A6NJP3|uniprotkb:P21851|uniprotkb:Q96J19|intact:EBI-8011909|intact:MINT-8395045|uniprotkb:Q7Z451|intact:EBI-28970775	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ap2b1_human(display_long)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000006125.18(gene)|ensembl:ENST00000621914.4(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0005048""(signal sequence binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030131""(clathrin adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0035904""(aorta development)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0060976""(coronary vasculature development)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|rcsb pdb:2IV8|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:P63010|rcsb pdb:1E42|rcsb pdb:2G30|rcsb pdb:2IV9|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:4UQI|rcsb pdb:5M5R|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6QH7|rcsb pdb:6URI|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|rcsb pdb:6YAI|rcsb pdb:7OG1|rcsb pdb:7OHO|rcsb pdb:7OM8|rcsb pdb:7Z5C|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|refseq:NP_001025177.1|refseq:NP_001273.1|refseq:XP_005257994.1|refseq:XP_005257995.1|refseq:XP_011522757.1|refseq:XP_016879773.1|refseq:XP_016879775.1|dip:DIP-33098N|panther:PTHR11134(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:Q5oFhdE1hcmqu7xLG3MteCu0Zcg9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P60228	intact:EBI-27055664	intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|ensembl:ENSP00000220849.5|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"ensembl:ENSG00000104408.11(gene)|ensembl:ENST00000220849.10(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000785""(chromatin)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0016605""(PML body)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071540""(eukaryotic translation initiation factor 3 complex, eIF3e)|go:""GO:1902416""(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8RG0|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001559.1|dip:DIP-32691N|panther:PTHR10317(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:s09LicCa0mb9WwO7esZvVdvUonY9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O14617	intact:EBI-27055664	intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055.4	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"efo:""Orphanet:664511""|dip:DIP-46793N|ensembl:ENSG00000065000.20(gene)|ensembl:ENST00000345016.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016182""(synaptic vesicle budding from endosome)|go:""GO:0016183""(synaptic vesicle coating)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0032438""(melanosome organization)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0043195""(terminal bouton)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046907""(intracellular transport)|go:""GO:0048007""(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0048499""(synaptic vesicle membrane organization)|go:""GO:0051138""(positive regulation of NK T cell differentiation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140916""(zinc ion import into lysosome)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|refseq:NP_001248755.1|refseq:NP_003929.4|efo:""Orphanet:1000""|efo:""Orphanet:54""|panther:PTHR22781(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O43795	intact:EBI-27055664	intact:EBI-351119|uniprotkb:O43794|uniprotkb:Q7Z6L5|ensembl:ENSP00000306382.4|ensembl:ENSP00000376132.3	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:myo1b_human(display_long)|uniprotkb:MYO1B(gene name)|psi-mi:MYO1B(display_short)|uniprotkb:Myosin I alpha(gene name synonym)|uniprotkb:MYH-1c(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_001123630.1|refseq:NP_001155291.1|refseq:NP_036355.2|refseq:XP_005246629.1|ensembl:ENSG00000128641.19(gene)|ensembl:ENST00000304164.8(transcript)|ensembl:ENST00000392318.8(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005903""(brush border)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016459""(myosin complex)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030175""(filopodium)|go:""GO:0045177""(apical part of cell)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O43795|panther:PTHR13140(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:FYYccaCMhkmUdTdtq4M8zdpFpV89606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:P61006	intact:EBI-27055664	intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935.2|intact:EBI-21356948	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_005361.2|ensembl:ENSG00000167461.12(gene)|rcsb pdb:6YX5|ensembl:ENST00000300935.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0007409""(axonogenesis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0010008""(endosome membrane)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0019003""(GDP binding)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030496""(midbody)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031489""(myosin V binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0048210""(Golgi vesicle fusion to target membrane)|go:""GO:0051223""(regulation of protein transport)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060170""(ciliary membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0097546""(ciliary base)|go:""GO:0097730""(non-motile cilium)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098969""(neurotransmitter receptor transport to postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099003""(vesicle-mediated transport in synapse)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-43703N|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O00203	intact:EBI-27055664	intact:EBI-1044383|uniprotkb:O00580|uniprotkb:Q7Z393|uniprotkb:Q9HD66|uniprotkb:E5RJ68|intact:EBI-10969499|ensembl:ENSP00000255194.7	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ap3b1_human(display_long)|uniprotkb:Adaptor protein complex AP-3 subunit beta-1(gene name synonym)|uniprotkb:Beta-3A-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta-1 large chain(gene name synonym)|uniprotkb:AP3B1(gene name)|psi-mi:AP3B1(display_short)|uniprotkb:ADTB3A(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"efo:""Orphanet:664500""|dip:DIP-24208N|ensembl:ENSG00000132842.16(gene)|ensembl:ENST00000255194.11(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003016""(respiratory system process)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006954""(inflammatory response)|go:""GO:0007040""(lysosome organization)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0007596""(blood coagulation)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030131""(clathrin adaptor complex)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0030851""(granulocyte differentiation)|go:""GO:0032438""(melanosome organization)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0036211""(protein modification process)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046907""(intracellular transport)|go:""GO:0048007""(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0051138""(positive regulation of NK T cell differentiation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0090152""(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:""GO:0098773""(skin epidermis development)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990742""(microvesicle)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|interpro:IPR029394|mint:O00203|reactome:R-HSA-432722|reactome:R-HSA-6802952|refseq:NP_001258698.1|refseq:NP_003655.3|panther:PTHR11134(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:+06UuQo62p9ALS7DiX+yKg7YRyg9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NJM6	uniprotkb:O95782	intact:EBI-27055664	intact:EBI-353552|uniprotkb:Q96CI7|uniprotkb:Q96PP6|uniprotkb:Q96PP7|uniprotkb:Q9H070|ensembl:ENSP00000351926.4|intact:EBI-28973302	psi-mi:a0a0h3njm6_salts(display_long)|uniprotkb:sopD2(gene name)|psi-mi:sopD2(display_short)|uniprotkb:G1W50_22020(orf name)|uniprotkb:G1W92_21480(orf name)|uniprotkb:G1X04_11385(orf name)|uniprotkb:G1X42_21485(orf name)|uniprotkb:SL1344_0909(locus name)	psi-mi:ap2a1_human(display_long)|uniprotkb:AP2A1(gene name)|psi-mi:AP2A1(display_short)|uniprotkb:ADTAA(gene name synonym)|uniprotkb:CLAPA1(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055677|imex:IM-29147-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033644""(host cell membrane)|mint:A0A0H3NJM6|refseq:WP_001145561.1|interpro:IPR022747"	"refseq:NP_055018.2|refseq:NP_570603.2|ensembl:ENSG00000196961.13(gene)|ensembl:ENST00000359032.10(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0006897""(endocytosis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030130""(clathrin coat of trans-Golgi network vesicle)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0032433""(filopodium tip)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098843""(postsynaptic endocytic zone)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900126""(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR050840|mint:O95782|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|dip:DIP-33164N|panther:PTHR22780(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:zKyqrp2xybQfHRFCoWRwoFTznTA216597	rogid:egkaIAhvIi1FqNr+8KEFeJaYZcc9606	intact-crc:13CD9BA4F96D9C07|rigid:8VTipIcXFUTskM/YBF28n2zPjzU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P35580	intact:EBI-10726196	intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45|ensembl:ENSP00000269243.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|interpro:IPR002928(Myosin tail)|ensembl:ENSG00000133026.14(gene)|ensembl:ENST00000269243.8(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0016459""(myosin complex)|go:""GO:0016460""(myosin II complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030048""(actin filament-based movement)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|go:""GO:0030496""(midbody)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032982""(myosin filament)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0042641""(actomyosin)|go:""GO:0043531""(ADP binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097513""(myosin II filament)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N|panther:PTHR45615(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O00410	intact:EBI-10726196	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219.3|ensembl:ENSP00000418393.1|ensembl:ENSP00000499125.1|intact:EBI-21353074	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_002262.3|refseq:XP_005254109.1|refseq:XP_005254110.1|ensembl:ENSG00000065150.21(gene)|ensembl:ENST00000357602.7(transcript)|ensembl:ENST00000490680.5(transcript)|ensembl:ENST00000651721.2(transcript)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003723""(RNA binding)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0006610""(ribosomal protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0045736""(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0071230""(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|refseq:XP_016876051.1|dip:DIP-41042N|panther:PTHR10527(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q99623	intact:EBI-10726196	intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875.1|uniprotkb:B4DP75	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001138303.1|refseq:NP_001254629.1|ensembl:ENSG00000215021.10(gene)|ensembl:ENST00000535923.6(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0009986""(cell surface)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030424""(axon)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0031536""(positive regulation of exit from mitosis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033147""(negative regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0033218""(amide binding)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0033600""(negative regulation of mammary gland epithelial cell proliferation)|go:""GO:0035632""(mitochondrial prohibitin complex)|go:""GO:0039529""(RIG-I signaling pathway)|go:""GO:0042113""(B cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046625""(sphingolipid binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050821""(protein stabilization)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060744""(mammary gland branching involved in thelarche)|go:""GO:0060749""(mammary gland alveolus development)|go:""GO:0060762""(regulation of branching involved in mammary gland duct morphogenesis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071944""(cell periphery)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1900208""(regulation of cardiolipin metabolic process)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902808""(positive regulation of cell cycle G1/S phase transition)|go:""GO:1904959""(regulation of cytochrome-c oxidase activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|rcsb pdb:8J4I|reactome:R-HSA-8949664|reactome:R-HSA-9840373|panther:PTHR23222(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:h4pib54mBeQgOKCe/hib58LM26w9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O14950	intact:EBI-10726196	intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500.5|ensembl:ENSP00000383037.5|ensembl:ENSP00000463559.1|ensembl:ENSP00000464464.1|ensembl:ENSP00000496809.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680.14(gene)|ensembl:ENST00000237500.10(transcript)|ensembl:ENST00000400175.9(transcript)|ensembl:ENST00000581193.5(transcript)|ensembl:ENST00000584539.1(transcript)|ensembl:ENST00000648965.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016460""(myosin II complex)|go:""GO:0030016""(myofibril)|go:""GO:0030018""(Z disc)|go:""GO:0032036""(myosin heavy chain binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|interpro:IPR050403|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|panther:PTHR23049(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P07099	intact:EBI-10726196	intact:EBI-6138796|uniprotkb:B2R8N0|uniprotkb:Q5VTJ6|uniprotkb:Q9NP75|uniprotkb:Q9NPE7|uniprotkb:Q9NQU6|uniprotkb:Q9NQU7|uniprotkb:Q9NQU8|uniprotkb:Q9NQU9|uniprotkb:Q9NQV0|uniprotkb:Q9NQV1|uniprotkb:Q9NQV2|ensembl:ENSP00000272167.5|ensembl:ENSP00000355802.4|ensembl:ENSP00000480004.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:hyep_human(display_long)|uniprotkb:EPHX1(gene name)|psi-mi:EPHX1(display_short)|uniprotkb:EPHX(gene name synonym)|uniprotkb:EPOX(gene name synonym)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000143819.13(gene)|ensembl:ENST00000272167.10(transcript)|ensembl:ENST00000366837.5(transcript)|ensembl:ENST00000614058.4(transcript)|go:""GO:0004301""(epoxide hydrolase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0009636""(response to toxic substance)|go:""GO:0019369""(arachidonate metabolic process)|go:""GO:0033961""(cis-stilbene-oxide hydrolase activity)|go:""GO:0097176""(epoxide metabolic process)|go:""GO:0120253""(hydrocarbon catabolic process)|go:""GO:1903165""(response to polycyclic arene)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|mint:P07099|reactome:R-HSA-211945|refseq:NP_000111.1|refseq:NP_001129490.1|refseq:NP_001278092.1|efo:""Orphanet:238475""|panther:PTHR21661(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:VtIgDuQpQQbLSdFLOBBx9yHHiBE9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O60518	intact:EBI-10726196	intact:EBI-1055771|uniprotkb:Q5T7X4|uniprotkb:Q7Z3V2|uniprotkb:Q96E78|ensembl:ENSP00000259569.5	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:rnbp6_human(display_long)|uniprotkb:RANBP6(gene name)|psi-mi:RANBP6(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_036548.1|ensembl:ENSG00000137040.10(gene)|ensembl:ENST00000259569.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0045202""(synapse)|go:""GO:0061608""(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|interpro:IPR041389|interpro:IPR041653|mint:O60518|refseq:NP_001230131.1|refseq:NP_001230132.1|panther:PTHR10527(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:3yh3vq2Bj+aqE9zWUU9LET7en6g9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P55884	intact:EBI-10726196	intact:EBI-366696|uniprotkb:Q2NL77|uniprotkb:Q9UMF9|uniprotkb:A4D208|intact:EBI-25643250|ensembl:ENSP00000354125.4|ensembl:ENSP00000380206.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:eif3b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:Prt1 homolog(gene name synonym)|uniprotkb:EIF3B(gene name)|psi-mi:EIF3B(display_short)|uniprotkb:EIF3S9(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR14068(orthology-group)|refseq:NP_001032360.1|refseq:NP_003742.2|ensembl:ENSG00000106263.19(gene)|ensembl:ENST00000360876.9(transcript)|ensembl:ENST00000397011.2(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0045202""(synapse)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071541""(eukaryotic translation initiation factor 3 complex, eIF3m)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0075525""(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:P55884|rcsb pdb:2KRB|rcsb pdb:2NLW|rcsb pdb:5K1H|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8XXN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_011513901.1|refseq:XP_011513902.1|refseq:XP_016868241.1|dip:DIP-31113N"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:MxQFPvmuOcO/S+4NqzToozWr8K89606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q13423	intact:EBI-10726196	intact:EBI-1391318|uniprotkb:Q16796|uniprotkb:Q2TB60|uniprotkb:Q8N3V4|ensembl:ENSP00000264663.5|ensembl:ENSP00000343873.4|ensembl:ENSP00000499249.1|ensembl:ENSP00000499281.1|ensembl:ENSP00000499494.1|ensembl:ENSP00000499527.1|ensembl:ENSP00000499611.1|ensembl:ENSP00000499639.1|intact:EBI-21355735	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:nntm_human(display_long)|uniprotkb:NNT(gene name)|psi-mi:NNT(display_short)|uniprotkb:Nicotinamide nucleotide transhydrogenase(gene name synonym)|uniprotkb:Pyridine nucleotide transhydrogenase(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR10160(orthology-group)|efo:""Orphanet:361""|ensembl:ENSG00000112992.18(gene)|ensembl:ENST00000264663.9(transcript)|ensembl:ENST00000344920.9(transcript)|ensembl:ENST00000653251.1(transcript)|ensembl:ENST00000656666.1(transcript)|ensembl:ENST00000662525.1(transcript)|ensembl:ENST00000669601.1(transcript)|ensembl:ENST00000670904.1(transcript)|ensembl:ENST00000671668.1(transcript)|go:""GO:0003957""(""NAD(P)+ transhydrogenase (Si-specific) activity"")|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006740""(NADPH regeneration)|go:""GO:0008750""(""proton-translocating NAD(P)+ transhydrogenase activity"")|go:""GO:0010918""(positive regulation of mitochondrial membrane potential)|go:""GO:0016020""(membrane)|go:""GO:0032364""(intracellular oxygen homeostasis)|go:""GO:0033273""(response to vitamin)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0098803""(respiratory chain complex)|go:""GO:0098869""(cellular oxidant detoxification)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903285""(positive regulation of hydrogen peroxide catabolic process)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|interpro:IPR024605|interpro:IPR026255|interpro:IPR029035|interpro:IPR034300|interpro:IPR036291|mint:Q13423|rcsb pdb:1DJL|rcsb pdb:1PT9|rcsb pdb:1U31|reactome:R-HSA-71403|refseq:NP_036475.3|refseq:NP_892022.2|refseq:XP_005248331.1|refseq:XP_011512303.1|refseq:XP_016864782.1"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:iDKBuEy/JvV9q3s4/aHuu58+Gyk9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P31040	intact:EBI-10726196	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q8IW48|uniprotkb:Q59GW8|uniprotkb:A8K5J6|ensembl:ENSP00000264932.6	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)|uniprotkb:Malate dehydrogenase [quinone] flavoprotein subunit(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000073578.18(gene)|ensembl:ENST00000264932.11(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006105""(succinate metabolic process)|go:""GO:0006121""(mitochondrial electron transport, succinate to ubiquinone)|go:""GO:0007399""(nervous system development)|go:""GO:0008177""(""succinate dehydrogenase (quinone) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045273""(""respiratory chain complex II (succinate dehydrogenase)"")|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR030664|interpro:IPR036188|interpro:IPR037099|mint:P31040|rcsb pdb:6VAX|rcsb pdb:8DYD|rcsb pdb:8DYE|rcsb pdb:8GS8|reactome:R-HSA-611105|reactome:R-HSA-71403|reactome:R-HSA-9854311|refseq:NP_001281261.1|refseq:NP_004159.2|efo:""Orphanet:154""|efo:""Orphanet:29072""|efo:""Orphanet:3208""|efo:""Orphanet:44890""|dip:DIP-45851N|panther:PTHR11632(orthology-group)|ensembl:ENSP00000264932.6|ensembl:ENST00000510361.5|ensembl:ENSP00000427703.1"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q14152	intact:EBI-10726196	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|uniprotkb:B4DYS1|uniprotkb:F5H335|ensembl:ENSP00000358140.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"panther:PTHR14005(orthology-group)|refseq:NP_003741.1|ensembl:ENSG00000107581.14(gene)|ensembl:ENST00000369144.8(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0002188""(translation reinitiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0043614""(multi-eIF complex)|go:""GO:0071540""(eukaryotic translation initiation factor 3 complex, eIF3e)|go:""GO:0071541""(eukaryotic translation initiation factor 3 complex, eIF3m)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0075525""(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|interpro:IPR054711|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8RG0|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P21796	intact:EBI-10726196	intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|ensembl:ENSP00000265333.3|ensembl:ENSP00000378484.3|ensembl:ENSP00000378487.2|uniprotkb:B3KVK4|uniprotkb:D3DQ93	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym)|uniprotkb:Voltage-dependent anion-selective channel protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000213585.11(gene)|ensembl:ENST00000265333.8(transcript)|ensembl:ENST00000395044.7(transcript)|ensembl:ENST00000395047.6(transcript)|go:""GO:0001662""(behavioral fear response)|go:""GO:0005244""(voltage-gated monoatomic ion channel activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005757""(mitochondrial permeability transition pore complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006820""(monoatomic anion transport)|go:""GO:0006869""(lipid transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007270""(neuron-neuron synaptic transmission)|go:""GO:0007612""(learning)|go:""GO:0008142""(oxysterol binding)|go:""GO:0008308""(voltage-gated monoatomic anion channel activity)|go:""GO:0015288""(porin activity)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0036444""(calcium import into the mitochondrion)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0046930""(pore complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097001""(ceramide binding)|go:""GO:0110099""(negative regulation of calcium import into the mitochondrion)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1990542""(mitochondrial transmembrane transport)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|rcsb pdb:7QI2|rcsb pdb:8J0O|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215|refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|panther:PTHR11743(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9NX40	intact:EBI-10726196	intact:EBI-2683029|uniprotkb:C9K030|uniprotkb:Q9BZE8|uniprotkb:G8JLN7|ensembl:ENSP00000264312.7|ensembl:ENSP00000370882.3|ensembl:ENSP00000423002.1|ensembl:ENSP00000423909.2	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ocad1_human(display_long)|uniprotkb:OCIA(gene name synonym)|uniprotkb:Ovarian carcinoma immunoreactive antigen(gene name synonym)|uniprotkb:OCIAD1(gene name)|psi-mi:OCIAD1(display_short)|uniprotkb:ASRIJ(gene name synonym)|uniprotkb:Ovarian cancer immunoreactive antigen domain containing 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001073309.1|refseq:NP_001073311.2|refseq:NP_001073308.1|refseq:NP_001073310.1|refseq:NP_060300.1|refseq:XP_016863818.1|ensembl:ENSG00000109180.15(gene)|ensembl:ENST00000264312.12(transcript)|ensembl:ENST00000381473.7(transcript)|ensembl:ENST00000508293.5(transcript)|ensembl:ENST00000513391.2(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006897""(endocytosis)|go:""GO:0016020""(membrane)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|go:""GO:2000736""(regulation of stem cell differentiation)|interpro:IPR009764(Ovarian carcinoma immunoreactive antigen)|interpro:IPR040187|mint:Q9NX40|panther:PTHR13336(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:e3Ojv8LBlgj056bssUZjEC+MB+Q9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9P0J0	intact:EBI-10726196	intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|ensembl:ENSP00000423673.1|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000186010.19(gene)|ensembl:ENST00000507754.9(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0009060""(aerobic respiration)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032981""(mitochondrial respiratory chain complex I assembly)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045039""(protein insertion into mitochondrial inner membrane)|go:""GO:0045271""(respiratory chain complex I)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098803""(respiratory chain complex)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9837999|refseq:NP_057049.5|efo:""Orphanet:146""|dip:DIP-31180N|panther:PTHR12966(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96A26	intact:EBI-10726196	intact:EBI-6123466|uniprotkb:Q9NRN6|uniprotkb:Q9UJX8|ensembl:ENSP00000419088.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:f162a_human(display_long)|uniprotkb:FAM162A(gene name)|psi-mi:FAM162A(display_short)|uniprotkb:C3orf28(gene name synonym)|uniprotkb:E2IG5(gene name synonym)|uniprotkb:E2-induced gene 5 protein(gene name synonym)|uniprotkb:Growth and transformation-dependent protein(gene name synonym)|uniprotkb:DC16(orf name)|uniprotkb:FWP001(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_055182.3|ensembl:ENSG00000114023.16(gene)|ensembl:ENST00000477892.5(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR009432(Protein of unknown function DUF1075)|mint:Q96A26|panther:PTHR13674(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:CjOkqa9wFwEOorjQt5oI7/EJ6709606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O75915	intact:EBI-10726196	intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_006398.1|ensembl:ENSG00000144746.7(gene)|ensembl:ENST00000273258.4(transcript)|go:""GO:0002037""(negative regulation of L-glutamate import across plasma membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0007611""(learning or memory)|go:""GO:0008631""(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:""GO:0010917""(negative regulation of mitochondrial membrane potential)|go:""GO:0015031""(protein transport)|go:""GO:0015813""(L-glutamate transmembrane transport)|go:""GO:0016020""(membrane)|go:""GO:0032874""(positive regulation of stress-activated MAPK cascade)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0051051""(negative regulation of transport)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098712""(L-glutamate import across plasma membrane)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|panther:PTHR12859(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P32189	intact:EBI-10726196	intact:EBI-3926629|ensembl:ENSP00000401720.2|uniprotkb:Q9UMP1|uniprotkb:Q9UMP0|uniprotkb:Q8IVR5|uniprotkb:B2R833|uniprotkb:A6NJP5|uniprotkb:Q6IQ27	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	"psi-mi:glpk_human(display_long)|uniprotkb:GK(gene name)|psi-mi:GK(display_short)|uniprotkb:""ATP:glycerol 3-phosphotransferase""(gene name synonym)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000198814.14(gene)|ensembl:ENST00000427190.6(transcript)|go:""GO:0004370""(glycerol kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006071""(glycerol metabolic process)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0019432""(triglyceride biosynthetic process)|go:""GO:0019563""(glycerol catabolic process)|go:""GO:0046167""(glycerol-3-phosphate biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000577(Carbohydrate kinase, FGGY)|interpro:IPR005999(Glycerol kinase)|interpro:IPR018483|interpro:IPR018484|interpro:IPR018485|interpro:IPR042018|interpro:IPR043129|mint:P32189|reactome:R-HSA-75109|refseq:NP_000158.1|refseq:NP_001121599.1|refseq:NP_001191948.1|refseq:NP_976325.1|efo:""Orphanet:284411""|efo:""Orphanet:284414""|panther:PTHR10196(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:LYCwq0sERytXdjbxIiDoDHcRaI89606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9BZZ5	intact:EBI-10726196	intact:EBI-1048422|uniprotkb:O15441|uniprotkb:Q9Y4J7|uniprotkb:D3DR21|uniprotkb:G3V1C3|uniprotkb:B4DRJ2|uniprotkb:B4DGR0|ensembl:ENSP00000431391.1|uniprotkb:B4E283	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:api5_human(display_long)|uniprotkb:Fibroblast growth factor 2-interacting factor(gene name synonym)|uniprotkb:Protein XAGL(gene name synonym)|uniprotkb:Antiapoptosis clone 11 protein(gene name synonym)|uniprotkb:Cell migration-inducing gene 8 protein(gene name synonym)|uniprotkb:API5(gene name)|psi-mi:API5(display_short)|uniprotkb:MIG8(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001136402.1|refseq:NP_001136403.1|refseq:NP_006586.1|refseq:NP_001230676.1|ensembl:ENSG00000166181.13(gene)|ensembl:ENST00000531273.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0017134""(fibroblast growth factor binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044346""(fibroblast apoptotic process)|go:""GO:2000270""(negative regulation of fibroblast apoptotic process)|interpro:IPR008383(Apoptosis inhibitory 5)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BZZ5|rcsb pdb:3U0R|rcsb pdb:3V6A|rcsb pdb:6L4O|panther:PTHR12758(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:WYNbM5GNolgFNszccnMEanszDgU9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P60228	intact:EBI-10726196	intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|ensembl:ENSP00000220849.5|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000104408.11(gene)|ensembl:ENST00000220849.10(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000785""(chromatin)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0016605""(PML body)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071540""(eukaryotic translation initiation factor 3 complex, eIF3e)|go:""GO:1902416""(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8RG0|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001559.1|dip:DIP-32691N|panther:PTHR10317(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:s09LicCa0mb9WwO7esZvVdvUonY9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P10606	intact:EBI-10726196	intact:EBI-1053725|uniprotkb:Q96J18|uniprotkb:Q99610|uniprotkb:Q53YB7|ensembl:ENSP00000258424.2|ensembl:ENSP00000517083.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:cox5b_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Vb(gene name synonym)|uniprotkb:COX5B(gene name)|psi-mi:COX5B(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001853.2|ensembl:ENSG00000135940.7(gene)|ensembl:ENSG00000291596.1(gene)|ensembl:ENST00000258424.3(transcript)|ensembl:ENST00000708077.1(transcript)|go:""GO:0004129""(cytochrome-c oxidase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006123""(mitochondrial electron transport, cytochrome c to oxygen)|go:""GO:0007585""(respiratory gaseous exchange by respiratory system)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0045277""(respiratory chain complex IV)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR036972|mint:P10606|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|reactome:R-HSA-9837999|reactome:R-HSA-9864848|panther:PTHR10122(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:EG8kMS2jKMWzQQokTXS2bYk4fHc9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P45880	intact:EBI-10726196	intact:EBI-354022|uniprotkb:Q5VWK1|uniprotkb:Q5VWK3|uniprotkb:Q6IB40|uniprotkb:Q7L3J5|uniprotkb:Q9BWK8|uniprotkb:Q9Y5I6|ensembl:ENSP00000361686.3|ensembl:ENSP00000443092.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:vdac2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001171712.1|refseq:NP_001171752.1|refseq:NP_003366.2|ensembl:ENSG00000165637.14(gene)|ensembl:ENST00000332211.11(transcript)|ensembl:ENST00000543351.5(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005244""(voltage-gated monoatomic ion channel activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006820""(monoatomic anion transport)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0008142""(oxysterol binding)|go:""GO:0008308""(voltage-gated monoatomic anion channel activity)|go:""GO:0015288""(porin activity)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032272""(negative regulation of protein polymerization)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045121""(membrane raft)|go:""GO:0045332""(phospholipid translocation)|go:""GO:0046930""(pore complex)|go:""GO:0097001""(ceramide binding)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097345""(mitochondrial outer membrane permeabilization)|go:""GO:1990542""(mitochondrial transmembrane transport)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|mint:P45880|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-8949215|refseq:NP_001311017.1|panther:PTHR11743(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:seQxCd19Z2HmpXcwb48osAuuafA9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O00232	intact:EBI-10726196	intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|uniprotkb:A6NP15|ensembl:ENSP00000348442.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:528084""|efo:""Orphanet:529962""|interpro:IPR036388|ensembl:ENSG00000197170.10(gene)|ensembl:ENST00000356126.8(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005838""(proteasome regulatory particle)|go:""GO:0008541""(proteasome regulatory particle, lid subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|interpro:IPR054559|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-5676590|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|refseq:NP_001303270.1|refseq:NP_002807.1|refseq:NP_777360.1|dip:DIP-27549N|panther:PTHR10855(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P61006	intact:EBI-10726196	intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935.2|intact:EBI-21356948	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_005361.2|ensembl:ENSG00000167461.12(gene)|rcsb pdb:6YX5|ensembl:ENST00000300935.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0007409""(axonogenesis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0010008""(endosome membrane)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0019003""(GDP binding)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030496""(midbody)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031489""(myosin V binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0048210""(Golgi vesicle fusion to target membrane)|go:""GO:0051223""(regulation of protein transport)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060170""(ciliary membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0097546""(ciliary base)|go:""GO:0097730""(non-motile cilium)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098969""(neurotransmitter receptor transport to postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099003""(vesicle-mediated transport in synapse)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-43703N|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:O14617	intact:EBI-10726196	intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:664511""|dip:DIP-46793N|ensembl:ENSG00000065000.20(gene)|ensembl:ENST00000345016.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016182""(synaptic vesicle budding from endosome)|go:""GO:0016183""(synaptic vesicle coating)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0032438""(melanosome organization)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0043195""(terminal bouton)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046907""(intracellular transport)|go:""GO:0048007""(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0048499""(synaptic vesicle membrane organization)|go:""GO:0051138""(positive regulation of NK T cell differentiation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140916""(zinc ion import into lysosome)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|refseq:NP_001248755.1|refseq:NP_003929.4|efo:""Orphanet:1000""|efo:""Orphanet:54""|panther:PTHR22781(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q53H12	intact:EBI-10726196	intact:EBI-2269837|uniprotkb:Q75KN1|uniprotkb:Q96GC3|uniprotkb:Q9NP48|ensembl:ENSP00000458417.2|ensembl:ENSP00000496789.1|ensembl:ENSP00000497280.1|ensembl:ENSP00000498112.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:agk_human(display_long)|uniprotkb:AGK(gene name)|psi-mi:AGK(display_short)|uniprotkb:MULK(gene name synonym)|uniprotkb:Multiple substrate lipid kinase(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000006530.18(gene)|ensembl:ENSG00000262327.7(gene)|ensembl:ENST00000575872.2(transcript)|ensembl:ENST00000648068.1(transcript)|ensembl:ENST00000649286.2(transcript)|ensembl:ENST00000650547.1(transcript)|go:""GO:0001729""(ceramide kinase activity)|go:""GO:0004143""(ATP-dependent diacylglycerol kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005829""(cytosol)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042721""(TIM22 mitochondrial import inner membrane insertion complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045039""(protein insertion into mitochondrial inner membrane)|go:""GO:0046486""(glycerolipid metabolic process)|go:""GO:0046513""(ceramide biosynthetic process)|go:""GO:0046834""(lipid phosphorylation)|go:""GO:0047620""(acylglycerol kinase activity)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR045579|interpro:IPR050187|mint:Q53H12|rcsb pdb:7CGP|reactome:R-HSA-1483206|reactome:R-HSA-6802952|refseq:NP_060708.1|refseq:XP_011514699.1|efo:""Orphanet:1369""|efo:""Orphanet:98994""|panther:PTHR12358(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:aUz/aYnkviiUE/ijNEddfOQmjZQ9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q96KA5	intact:EBI-10726196	intact:EBI-3216282|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1|ensembl:ENSP00000313854.5|ensembl:ENSP00000480372.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:clp1l_human(display_long)|uniprotkb:Cleft lip and palate transmembrane protein 1-like protein(gene name synonym)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_110409.2|ensembl:ENSG00000049656.14(gene)|ensembl:ENSG00000274811.3(gene)|ensembl:ENST00000320895.10(transcript)|ensembl:ENST00000620010.3(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0017128""(phospholipid scramblase activity)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|mint:Q96KA5|panther:PTHR21347(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q13620	intact:EBI-10726196	intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084.1|ensembl:ENSP00000505176.1|ensembl:ENSP00000506259.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:85293""|ensembl:ENSG00000158290.19(gene)|ensembl:ENST00000680673.1(transcript)|ensembl:ENST00000681253.1(transcript)|ensembl:ENST00000681652.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0010467""(gene expression)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031175""(neuron projection development)|go:""GO:0031464""(Cul4A-RING E3 ubiquitin ligase complex)|go:""GO:0031465""(Cul4B-RING E3 ubiquitin ligase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070914""(UV-damage excision repair)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|interpro:IPR045093|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|rcsb pdb:8EI1|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|refseq:NP_001073341.1|refseq:NP_003579.3|refseq:XP_011529702.1|dip:DIP-31609N|panther:PTHR11932(orthology-group)|ensembl:ENST00000371322.11|ensembl:ENSP00000360373.5|ensembl:ENST00000371323.3|ensembl:ENSP00000360374.3|ensembl:ENSP00000505084.1|ensembl:ENSP00000506259.1|ensembl:ENSP00000505176.1"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q15836	intact:EBI-10726196	intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666.6	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_004772.1|ensembl:ENSG00000049245.13(gene)|ensembl:ENST00000054666.11(transcript)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0030133""(transport vesicle)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061025""(membrane fusion)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:1903531""(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-56422N|panther:PTHR45701(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q07812	intact:EBI-10726196	intact:EBI-516580|uniprotkb:P55269|uniprotkb:Q07814|uniprotkb:Q07815|uniprotkb:Q8WZ49|uniprotkb:Q9NR76|uniprotkb:Q9UQD6|uniprotkb:Q9NYG7|uniprotkb:Q9UCZ6|uniprotkb:Q9UCZ7|uniprotkb:A8K4W1|intact:EBI-8995042|ensembl:ENSP00000263262.9	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:bax_human(display_long)|uniprotkb:BAX(gene name)|psi-mi:BAX(display_short)|uniprotkb:BCL2L4(gene name synonym)|uniprotkb:Bcl-2-like protein 4(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_004315.1|refseq:NP_620116.1|refseq:NP_620118.1|refseq:NP_620119.2|refseq:XP_016882566.1|refseq:NP_001278357.1|refseq:NP_001278360.1|ensembl:ENSG00000087088.21(gene)|ensembl:ENST00000345358.12(transcript)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0001764""(neuron migration)|go:""GO:0001777""(T cell homeostatic proliferation)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001783""(B cell apoptotic process)|go:""GO:0001822""(kidney development)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002262""(myeloid cell homeostasis)|go:""GO:0002352""(B cell negative selection)|go:""GO:0002358""(B cell homeostatic proliferation)|go:""GO:0002904""(positive regulation of B cell apoptotic process)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005757""(mitochondrial permeability transition pore complex)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006687""(glycosphingolipid metabolic process)|go:""GO:0006808""(regulation of nitrogen utilization)|go:""GO:0006915""(apoptotic process)|go:""GO:0007281""(germ cell development)|go:""GO:0008053""(mitochondrial fusion)|go:""GO:0008289""(lipid binding)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0008637""(apoptotic mitochondrial changes)|go:""GO:0009566""(fertilization)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009651""(response to salt stress)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010524""(positive regulation of calcium ion transport into cytosol)|go:""GO:0010917""(negative regulation of mitochondrial membrane potential)|go:""GO:0015267""(channel activity)|go:""GO:0016020""(membrane)|go:""GO:0021854""(hypothalamus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0032471""(negative regulation of endoplasmic reticulum calcium ion concentration)|go:""GO:0032976""(release of matrix enzymes from mitochondria)|go:""GO:0033599""(regulation of mammary gland epithelial cell proliferation)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035234""(ectopic germ cell programmed cell death)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0045136""(development of secondary sexual characteristics)|go:""GO:0046666""(retinal cell programmed cell death)|go:""GO:0046930""(pore complex)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048087""(positive regulation of developmental pigmentation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048515""(spermatid differentiation)|go:""GO:0048597""(post-embryonic camera-type eye morphogenesis)|go:""GO:0048678""(response to axon injury)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0051204""(protein insertion into mitochondrial membrane)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0060011""(Sertoli cell proliferation)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0060057""(apoptotic process involved in mammary gland involution)|go:""GO:0060058""(positive regulation of apoptotic process involved in mammary gland involution)|go:""GO:0060068""(vagina development)|go:""GO:0060402""(calcium ion transport into cytosol)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070242""(thymocyte apoptotic process)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097136""(Bcl-2 family protein complex)|go:""GO:0097144""(BAX complex)|go:""GO:0097145""(BAK complex)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:0098586""(cellular response to virus)|go:""GO:1902110""(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902262""(apoptotic process involved in blood vessel morphogenesis)|go:""GO:1902263""(apoptotic process involved in embryonic digit morphogenesis)|go:""GO:1902445""(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)|go:""GO:1902512""(positive regulation of apoptotic DNA fragmentation)|go:""GO:1903896""(positive regulation of IRE1-mediated unfolded protein response)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|go:""GO:1990117""(B cell receptor apoptotic signaling pathway)|go:""GO:2000243""(positive regulation of reproductive process)|go:""GO:2000673""(positive regulation of motor neuron apoptotic process)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR036834|interpro:IPR046371|mint:Q07812|rcsb pdb:1F16|rcsb pdb:2G5B|rcsb pdb:2K7W|rcsb pdb:2LR1|rcsb pdb:3PK1|rcsb pdb:3PL7|rcsb pdb:4BD2|rcsb pdb:4BD6|rcsb pdb:4BD7|rcsb pdb:4BD8|rcsb pdb:4BDU|rcsb pdb:4S0O|rcsb pdb:4S0P|rcsb pdb:4UF2|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIG|rcsb pdb:4ZIH|rcsb pdb:4ZII|rcsb pdb:5W5X|rcsb pdb:5W5Z|rcsb pdb:5W60|rcsb pdb:5W61|rcsb pdb:6EB6|rcsb pdb:6L8V|rcsb pdb:6L95|rcsb pdb:6TRR|rcsb pdb:6XY6|rcsb pdb:7ADT|rcsb pdb:8G1T|rcsb pdb:8SPE|rcsb pdb:8SPF|rcsb pdb:8SPZ|rcsb pdb:8SRX|rcsb pdb:8SRY|rcsb pdb:8SVK|reactome:R-HSA-111457|reactome:R-HSA-114294|reactome:R-HSA-5620971|reactome:R-HSA-6803204|reactome:R-HSA-6804114|reactome:R-HSA-8878166|reactome:R-HSA-9603505|dip:DIP-232N|panther:PTHR11256(orthology-group)|ensembl:ENST00000293288.12|ensembl:ENSP00000293288.8|ensembl:ENSP00000263262.9|ensembl:ENST00000354470.7|ensembl:ENSP00000346461.3|ensembl:ENST00000356483.8|ensembl:ENSP00000348871.4|ensembl:ENST00000415969.6|ensembl:ENSP00000389971.2|ensembl:ENST00000515540.5|ensembl:ENSP00000426328.1"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:+Fz2No3HFxN4vZ+KGhDcgPQhpLo9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q16850	intact:EBI-10726196	intact:EBI-2680495|intact:EBI-21358836|uniprotkb:A0A0C4DFL7|uniprotkb:O00770|uniprotkb:Q99868|uniprotkb:Q8N1A8|uniprotkb:O00772|uniprotkb:Q16784|uniprotkb:B2RAI4|uniprotkb:B4DJ55|uniprotkb:A4D1F8|ensembl:ENSP00000003100.8	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:cp51a_human(display_long)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450 51A1(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:Cytochrome P450LI(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:CYP51A1(gene name)|psi-mi:CYP51A1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"efo:""Orphanet:521432""|ensembl:ENSG00000001630.18(gene)|ensembl:ENST00000003100.13(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006694""(steroid biosynthetic process)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0008398""(sterol 14-demethylase activity)|go:""GO:0016020""(membrane)|go:""GO:0016125""(sterol metabolic process)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016712""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:""GO:0020037""(heme binding)|go:""GO:0033488""(cholesterol biosynthetic process via 24,25-dihydrolanosterol)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0050709""(negative regulation of protein secretion)|go:""GO:1900222""(negative regulation of amyloid-beta clearance)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002403(Cytochrome P450, E-class, group IV)|interpro:IPR017972|interpro:IPR036396|interpro:IPR050529|mint:Q16850|rcsb pdb:3JUS|rcsb pdb:3JUV|rcsb pdb:3LD6|rcsb pdb:4UHI|rcsb pdb:4UHL|rcsb pdb:6Q2T|rcsb pdb:6UEZ|rcsb pdb:8SBI|rcsb pdb:8SS0|reactome:R-HSA-191273|reactome:R-HSA-211976|reactome:R-HSA-2426168|reactome:R-HSA-9619665|refseq:NP_000777.1|refseq:NP_001139624.1|panther:PTHR24286(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:yrFu9QoUi7oRnhwLxzbC3e/jhUE9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:P30519	intact:EBI-10726196	intact:EBI-712096|uniprotkb:I3L430|uniprotkb:O60605|uniprotkb:A8MT35|uniprotkb:D3DUD5|ensembl:ENSP00000219700.6|ensembl:ENSP00000381595.3|ensembl:ENSP00000385100.2|ensembl:ENSP00000391637.1|ensembl:ENSP00000394103.3|ensembl:ENSP00000459214.1|ensembl:ENSP00000478785.1|ensembl:ENSP00000481295.1|ensembl:ENSP00000481811.1|ensembl:ENSP00000483319.2|ensembl:ENSP00000484422.1|ensembl:ENSP00000484423.1|ensembl:ENSP00000484467.1|ensembl:ENSP00000487673.1|ensembl:ENSP00000488579.1|ensembl:ENSP00000488880.1	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:hmox2_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)|uniprotkb:HO2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001273196.1|refseq:NP_001273197.1|refseq:NP_001273198.1|refseq:NP_001273199.1|refseq:NP_001273200.1|refseq:NP_001120676.1|refseq:NP_001120677.1|refseq:NP_001120678.1|refseq:NP_002125.3|refseq:XP_016878685.1|refseq:XP_016878686.1|dip:DIP-53564N|ensembl:ENSG00000103415.12(gene)|ensembl:ENSG00000277424.4(gene)|ensembl:ENST00000219700.10(transcript)|ensembl:ENST00000398595.7(transcript)|ensembl:ENST00000406590.6(transcript)|ensembl:ENST00000414777.5(transcript)|ensembl:ENST00000458134.7(transcript)|ensembl:ENST00000570646.6(transcript)|ensembl:ENST00000612525.4(transcript)|ensembl:ENST00000615778.4(transcript)|ensembl:ENST00000619528.4(transcript)|ensembl:ENST00000619913.4(transcript)|ensembl:ENST00000620445.3(transcript)|ensembl:ENST00000621065.4(transcript)|ensembl:ENST00000622146.4(transcript)|ensembl:ENST00000631540.1(transcript)|ensembl:ENST00000631677.1(transcript)|ensembl:ENST00000632458.1(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0004392""(""heme oxygenase (decyclizing) activity"")|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006788""(heme oxidation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042167""(heme catabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:P30519|rcsb pdb:2Q32|rcsb pdb:2QPP|rcsb pdb:2RGZ|rcsb pdb:4WMH|rcsb pdb:5UC8|rcsb pdb:5UC9|rcsb pdb:5UCA|reactome:R-HSA-189483|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-917937|reactome:R-HSA-9707564|panther:PTHR10720(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:yTwXdEjnQgfiFBvl5fhcCwDOJWo9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q8TC12	intact:EBI-10726196	intact:EBI-2823756|uniprotkb:Q0QD40|uniprotkb:B4DDW0|uniprotkb:A8K062|uniprotkb:B2RB26|uniprotkb:A6NDK3|uniprotkb:Q6IAH5|uniprotkb:Q9NRW0|uniprotkb:Q9Y391|ensembl:ENSP00000370750.4	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:rdh11_human(display_long)|uniprotkb:RDH11(gene name)|psi-mi:RDH11(display_short)|uniprotkb:ARSDR1(gene name synonym)|uniprotkb:PSDR1(gene name synonym)|uniprotkb:Androgen-regulated short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:HCV core-binding protein HCBP12(gene name synonym)|uniprotkb:Prostate short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:Retinal reductase 1(gene name synonym)|uniprotkb:SDR7C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 7C member 1(gene name synonym)|uniprotkb:CGI-82(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000072042.13(gene)|ensembl:ENST00000381346.9(transcript)|go:""GO:0001523""(retinoid metabolic process)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0004745""(""all-trans-retinol dehydrogenase (NAD+) activity"")|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007601""(visual perception)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0033721""(""aldehyde dehydrogenase (NADP+) activity"")|go:""GO:0042572""(retinol metabolic process)|go:""GO:0042574""(retinal metabolic process)|go:""GO:0052650""(""all-trans-retinol dehydrogenase (NADP+) activity"")|go:""GO:0102354""(11-cis-retinol dehydrogenase activity)|go:""GO:0110095""(cellular detoxification of aldehyde)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q8TC12|reactome:R-HSA-2453902|reactome:R-HSA-5365859|reactome:R-HSA-975634|refseq:NP_001239579.1|refseq:NP_057110.3|efo:""Orphanet:436245""|panther:PTHR24320(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:elUutgO+T5gnwthTzc4WDetnuug9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NB75	uniprotkb:Q9BTX1	intact:EBI-10726196	intact:EBI-2552800|uniprotkb:Q9NVZ7|uniprotkb:Q9H9T6|uniprotkb:Q9NSG3|uniprotkb:Q9NSG4|uniprotkb:Q8NB76|uniprotkb:B4DHA3|uniprotkb:B4DQQ5|uniprotkb:G3XA81|ensembl:ENSP00000360483.3	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:ndc1_human(display_long)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:TMEM48(gene name synonym)|uniprotkb:Transmembrane protein 48(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055718|imex:IM-29147-25	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"refseq:NP_001162023.1|refseq:NP_060557.3|ensembl:ENSG00000058804.12(gene)|ensembl:ENST00000371429.4(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006999""(nuclear pore organization)|go:""GO:0007129""(homologous chromosome pairing at meiosis)|go:""GO:0007283""(spermatogenesis)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031965""(nuclear membrane)|go:""GO:0051028""(mRNA transport)|go:""GO:0051292""(nuclear pore complex assembly)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0070762""(nuclear pore transmembrane ring)|interpro:IPR019049|mint:Q9BTX1|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9705671|panther:PTHR13269(orthology-group)"	-	-	-	figure legend:ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:0HbFqC4o16ELLTSUfqACs1BD05I9606	intact-crc:F93186F3365E08CE|rigid:qeB2nAKmUYymuNXLVWhc98aROzM	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O14654	intact:EBI-27055396	intact:EBI-356594|ensembl:ENSP00000505547.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_003595.1|ensembl:ENSG00000133124.12(gene)|ensembl:ENST00000564206.2(transcript)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|mint:O14654|reactome:R-HSA-2428928|panther:PTHR10614(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9Y2J2	intact:EBI-27055396	intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158.2|uniprotkb:B7Z4I5|uniprotkb:F5GX05	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397.18(gene)|ensembl:ENST00000341928.7(transcript)|go:""GO:0002175""(protein localization to paranode region of axon)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006915""(apoptotic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0030054""(cell junction)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0030913""(paranodal junction assembly)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0033270""(paranode region of axon)|go:""GO:0043217""(myelin maintenance)|go:""GO:0044224""(juxtaparanode region of axon)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0071205""(protein localization to juxtaparanode region of axon)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098696""(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0106006""(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N|panther:PTHR23280(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O43491	intact:EBI-27055396	intact:EBI-1052044|uniprotkb:Q5T4F0|uniprotkb:B4DHI8|uniprotkb:Q68DV2|uniprotkb:E9PPD9|ensembl:ENSP00000338481.3|ensembl:ENSP00000357110.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:e41l2_human(display_long)|uniprotkb:Generally expressed protein 4.1(gene name synonym)|uniprotkb:EPB41L2(gene name)|psi-mi:EPB41L2(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001422.1|refseq:NP_001129026.1|refseq:NP_001129027.1|refseq:NP_001239589.1|refseq:XP_011533832.1|refseq:XP_011533836.1|refseq:XP_016865844.1|refseq:XP_016865848.1|refseq:XP_016865849.1|refseq:XP_016865850.1|refseq:XP_016865851.1|dip:DIP-17034N|ensembl:ENSG00000079819.20(gene)|ensembl:ENST00000337057.8(transcript)|ensembl:ENST00000368128.6(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0008091""(spectrin)|go:""GO:0030054""(cell junction)|go:""GO:0030507""(spectrin binding)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0042731""(PH domain binding)|go:""GO:0051301""(cell division)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904778""(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|mint:O43491|reactome:R-HSA-6794361|panther:PTHR23280(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:QvhY6g+bBqTBR8oHl/php27Wb7Y9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q96RT1	intact:EBI-27055396	intact:EBI-993903|uniprotkb:Q86W38|uniprotkb:Q9NR18|uniprotkb:Q9NW48|uniprotkb:Q9ULJ5|uniprotkb:A0AVR1|uniprotkb:B4E3F1|uniprotkb:B7ZLV9|uniprotkb:E9PCR8|uniprotkb:Q1RMD0|uniprotkb:E7EQW9|ensembl:ENSP00000284037.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:erbin_human(display_long)|uniprotkb:ERBIN(gene name)|psi-mi:ERBIN(display_short)|uniprotkb:Densin-180-like protein(gene name synonym)|uniprotkb:ERBB2IP(gene name synonym)|uniprotkb:Erbb2-interacting protein(gene name synonym)|uniprotkb:KIAA1225(gene name synonym)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Protein LAP2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:656912""|ensembl:ENSG00000112851.16(gene)|ensembl:ENST00000284037.10(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005176""(ErbB-2 class receptor binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005604""(basement membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030054""(cell junction)|go:""GO:0030056""(hemidesmosome)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0045175""(basal protein localization)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0070433""(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071638""(negative regulation of monocyte chemotactic protein-1 production)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099572""(postsynaptic specialization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|interpro:IPR050614|mint:Q96RT1|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1N7T|rcsb pdb:2H3L|rcsb pdb:2QBW|rcsb pdb:3CH8|rcsb pdb:6Q0M|rcsb pdb:6Q0N|rcsb pdb:6Q0U|rcsb pdb:6UBH|rcsb pdb:7LUL|reactome:R-HSA-1227986|reactome:R-HSA-8863795|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|refseq:NP_001006600.1|refseq:NP_001240626.1|refseq:NP_001240627.1|refseq:NP_001240628.1|refseq:NP_001240630.1|refseq:NP_061165.1|panther:PTHR45752(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:kITHWAgafb7t7RFgzs5ff7XCL3Y9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P55196	intact:EBI-27055396	intact:EBI-365875|uniprotkb:O75089|uniprotkb:Q5TIG6|uniprotkb:O75087|uniprotkb:O75088|uniprotkb:Q9NSN7|uniprotkb:Q9NU92|uniprotkb:Q5TIG7|uniprotkb:Q59FP0|ensembl:ENSP00000404595.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:afad_human(display_long)|uniprotkb:AFDN(gene name)|psi-mi:AFDN(display_short)|uniprotkb:AF6(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 6 protein(gene name synonym)|uniprotkb:Afadin adherens junction formation factor(gene name synonym)|uniprotkb:MLLT4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:XP_005267053.1|rcsb pdb:5A6C|rcsb pdb:7QCR|refseq:NP_001035089.1|refseq:NP_001193937.1|refseq:NP_001278893.1|reactome:R-HSA-418990|ensembl:ENSG00000130396.22(gene)|ensembl:ENST00000447894.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016607""(nuclear speck)|go:""GO:0022409""(positive regulation of cell-cell adhesion)|go:""GO:0030054""(cell junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045296""(cadherin binding)|go:""GO:0046930""(pore complex)|go:""GO:0046931""(pore complex assembly)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0061951""(establishment of protein localization to plasma membrane)|go:""GO:0070160""(tight junction)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0090557""(establishment of endothelial intestinal barrier)|go:""GO:2000049""(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR028842|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977|mint:P55196|rcsb pdb:1T2M|rcsb pdb:1XZ9|rcsb pdb:2AIN|rcsb pdb:2EXG|panther:PTHR10398(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:x7kK5K1+wAFZFdVopvQ/l496J5U9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q03001	intact:EBI-27055396	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783|uniprotkb:E7ERU0	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:314381""|efo:""Orphanet:412181""|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005882""(intermediate filament)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008017""(microtubule binding)|go:""GO:0008090""(retrograde axonal transport)|go:""GO:0009611""(response to wounding)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0030018""(Z disc)|go:""GO:0030056""(hemidesmosome)|go:""GO:0030424""(axon)|go:""GO:0031252""(cell leading edge)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031581""(hemidesmosome assembly)|go:""GO:0031673""(H zone)|go:""GO:0035371""(microtubule plus-end)|go:""GO:0042060""(wound healing)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0048870""(cell motility)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|interpro:IPR049538|mint:Q03001|rcsb pdb:3GJO|rcsb pdb:7OLG|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_001714.1|refseq:NP_056363.2|refseq:NP_899236.1|refseq:XP_016866713.1|dip:DIP-33131N|panther:PTHR23169(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q14739	intact:EBI-27055396	intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163.4|ensembl:ENSP00000339883.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:""3-beta-hydroxysterol Delta (14)-reductase""(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:1426""|efo:""Orphanet:448267""|efo:""Orphanet:779""|dip:DIP-5987N|ensembl:ENSG00000143815.15(gene)|ensembl:ENST00000272163.9(transcript)|ensembl:ENST00000338179.6(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0030223""(neutrophil differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0050613""(Delta14-sterol reductase activity)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0070087""(chromo shadow domain binding)|go:""GO:0070402""(NADPH binding)|go:""GO:0140463""(chromatin-protein adaptor activity)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|panther:PTHR21257(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O15498	intact:EBI-27055396	intact:EBI-4402903|uniprotkb:Q53F01|uniprotkb:Q6FGU9|uniprotkb:Q6IB15|uniprotkb:B4DR94|ensembl:ENSP00000223369.2|ensembl:ENSP00000504623.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ykt6_human(display_long)|uniprotkb:YKT6(gene name)|psi-mi:YKT6(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_006546.1|refseq:XP_016867171.1|ensembl:ENSG00000106636.9(gene)|ensembl:ENST00000223369.3(transcript)|ensembl:ENST00000679020.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006903""(vesicle targeting)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0030133""(transport vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045296""(cadherin binding)|go:""GO:0097440""(apical dendrite)|go:""GO:0097441""(basal dendrite)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR045848|mint:O15498|rcsb pdb:6J74|rcsb pdb:6J7F|rcsb pdb:6J7X|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9013423|panther:PTHR45806(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:pkTOoQ9XXEVYHKNvqOMCU6x4nZg9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P42166	intact:EBI-27055396	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_003267.1|ensembl:ENSG00000120802.15(gene)|ensembl:ENST00000266732.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0045296""(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|interpro:IPR051656|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F|rcsb pdb:8FN7|rcsb pdb:8FND|rcsb pdb:8FNG|rcsb pdb:8FNH|rcsb pdb:8FNJ|rcsb pdb:8FNL|rcsb pdb:8FNM|rcsb pdb:8FNN|rcsb pdb:8FNO|rcsb pdb:8FNP|rcsb pdb:8FNQ|panther:PTHR12019(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P55011	intact:EBI-27055396	intact:EBI-2801449|uniprotkb:Q8WWH7|uniprotkb:Q8N713|ensembl:ENSP00000262461.2|intact:EBI-28983018	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:s12a2_human(display_long)|uniprotkb:Na-K-2Cl cotransporter 1(gene name synonym)|uniprotkb:NKCC1(gene name synonym)|uniprotkb:Basolateral Na-K-Cl symporter(gene name synonym)|uniprotkb:SLC12A2(gene name)|psi-mi:SLC12A2(display_short)|uniprotkb:""Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2""(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000064651.14(gene)|ensembl:ENST00000262461.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0006972""(hyperosmotic response)|go:""GO:0007214""(gamma-aminobutyric acid signaling pathway)|go:""GO:0008511""(""sodium:potassium:chloride symporter activity"")|go:""GO:0008519""(ammonium channel activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010818""(T cell chemotaxis)|go:""GO:0015079""(potassium ion transmembrane transporter activity)|go:""GO:0015377""(""chloride:monoatomic cation symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030321""(transepithelial chloride transport)|go:""GO:0030644""(intracellular chloride ion homeostasis)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031253""(cell projection membrane)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0035865""(cellular response to potassium ion)|go:""GO:0042995""(cell projection)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044297""(cell body)|go:""GO:0044298""(cell body membrane)|go:""GO:0045795""(positive regulation of cell volume)|go:""GO:0046873""(metal ion transmembrane transporter activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0055064""(chloride ion homeostasis)|go:""GO:0055075""(potassium ion homeostasis)|go:""GO:0055078""(sodium ion homeostasis)|go:""GO:0061044""(negative regulation of vascular wound healing)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070634""(transepithelial ammonium transport)|go:""GO:0071944""(cell periphery)|go:""GO:0072488""(ammonium transmembrane transport)|go:""GO:0098658""(inorganic anion import across plasma membrane)|go:""GO:0098659""(inorganic cation import across plasma membrane)|go:""GO:0098719""(sodium ion import across plasma membrane)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902476""(chloride transmembrane transport)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904450""(positive regulation of aspartate secretion)|go:""GO:1904464""(regulation of matrix metallopeptidase secretion)|go:""GO:1990573""(potassium ion import across plasma membrane)|go:""GO:1990869""(cellular response to chemokine)|interpro:IPR002443(Na-K-Cl co-transporter)|interpro:IPR002444(Na-K-Cl co-transporter 1)|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004842(Na-K-Cl cotransporter superfamily)|interpro:IPR013612(Amino acid permease N-terminal)|interpro:IPR018491|mint:P55011|rcsb pdb:6PZT|rcsb pdb:7D10|rcsb pdb:7MXO|rcsb pdb:7N3N|rcsb pdb:7S1X|rcsb pdb:7S1Y|rcsb pdb:7S1Z|rcsb pdb:7SFL|rcsb pdb:7SMP|rcsb pdb:7ZGO|rcsb pdb:8STE|reactome:R-HSA-426117|refseq:NP_001037.1|dip:DIP-43979N|efo:""Orphanet:633021""|efo:""Orphanet:633024""|panther:PTHR11827(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:DJ/f5e8b/aBlnCcWYxYUa/mcoFY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P29317	intact:EBI-27055396	intact:EBI-702104|uniprotkb:Q8N3Z2|ensembl:ENSP00000351209.5|uniprotkb:B5A968|intact:EBI-28989000	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:epha2_human(display_long)|uniprotkb:Tyrosine-protein kinase receptor ECK(gene name synonym)|uniprotkb:Epithelial cell kinase(gene name synonym)|uniprotkb:EPHA2(gene name)|psi-mi:EPHA2(display_short)|uniprotkb:ECK(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000142627.13(gene)|ensembl:ENST00000358432.8(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0002043""(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008288""(boss receptor activity)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009986""(cell surface)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0014028""(notochord formation)|go:""GO:0016477""(cell migration)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019838""(growth factor binding)|go:""GO:0021915""(neural tube development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0043235""(receptor complex)|go:""GO:0043535""(regulation of blood vessel endothelial cell migration)|go:""GO:0045296""(cadherin binding)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0046058""(cAMP metabolic process)|go:""GO:0046849""(bone remodeling)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048320""(axial mesoderm formation)|go:""GO:0048870""(cell motility)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0060035""(notochord cell development)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0060444""(branching involved in mammary gland duct morphogenesis)|go:""GO:0070160""(tight junction)|go:""GO:0070309""(lens fiber cell morphogenesis)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070848""(response to growth factor)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1901491""(negative regulation of lymphangiogenesis)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1904238""(pericyte cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034263|interpro:IPR036116|interpro:IPR050449|mint:P29317|rcsb pdb:1MQB|rcsb pdb:2E8N|rcsb pdb:2K9Y|rcsb pdb:2KSO|rcsb pdb:2X10|rcsb pdb:2X11|rcsb pdb:3C8X|rcsb pdb:3CZU|rcsb pdb:3FL7|rcsb pdb:3HEI|rcsb pdb:3HPN|rcsb pdb:3KKA|rcsb pdb:3MBW|rcsb pdb:3MX0|rcsb pdb:3SKJ|rcsb pdb:4P2K|rcsb pdb:4PDO|rcsb pdb:4TRL|rcsb pdb:5EK7|rcsb pdb:5I9U|rcsb pdb:5I9V|rcsb pdb:5I9W|rcsb pdb:5I9X|rcsb pdb:5I9Y|rcsb pdb:5I9Z|rcsb pdb:5IA0|rcsb pdb:5IA1|rcsb pdb:5IA2|rcsb pdb:5IA3|rcsb pdb:5IA4|rcsb pdb:5IA5|rcsb pdb:5NJZ|rcsb pdb:5NK0|rcsb pdb:5NK1|rcsb pdb:5NK2|rcsb pdb:5NK3|rcsb pdb:5NK4|rcsb pdb:5NK5|rcsb pdb:5NK6|rcsb pdb:5NK7|rcsb pdb:5NK8|rcsb pdb:5NK9|rcsb pdb:5NKA|rcsb pdb:5NKB|rcsb pdb:5NKC|rcsb pdb:5NKD|rcsb pdb:5NKE|rcsb pdb:5NKF|rcsb pdb:5NKG|rcsb pdb:5NKH|rcsb pdb:5NKI|rcsb pdb:5NZ9|rcsb pdb:6B9L|rcsb pdb:6F7M|rcsb pdb:6F7N|rcsb pdb:6FNF|rcsb pdb:6NK1|rcsb pdb:6FNG|rcsb pdb:6FNH|rcsb pdb:6HES|rcsb pdb:6HET|rcsb pdb:6HEU|rcsb pdb:6HEV|rcsb pdb:6HEW|rcsb pdb:6HEX|rcsb pdb:6HEY|rcsb pdb:6NJZ|rcsb pdb:6NK0|rcsb pdb:6NK2|rcsb pdb:6NKP|rcsb pdb:6Q7B|rcsb pdb:6Q7C|rcsb pdb:6Q7D|rcsb pdb:6Q7E|rcsb pdb:6Q7F|rcsb pdb:6Q7G|rcsb pdb:6RW2|rcsb pdb:7B7N|rcsb pdb:7CZE|rcsb pdb:7CZF|rcsb pdb:7KJA|rcsb pdb:7KJB|rcsb pdb:7KJC|rcsb pdb:8BIN|rcsb pdb:8BIO|rcsb pdb:8BK0|rcsb pdb:8BM8|rcsb pdb:8BOC|rcsb pdb:8BOD|rcsb pdb:8BOF|rcsb pdb:8BOG|rcsb pdb:8BOH|rcsb pdb:8BOI|rcsb pdb:8BOK|rcsb pdb:8BOM|rcsb pdb:8QQY|rcsb pdb:8T9B|rcsb pdb:8TRS|rcsb pdb:8TRT|rcsb pdb:8TRV|rcsb pdb:8TV1|rcsb pdb:8TV5|rcsb pdb:8XPV|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_004422.2|efo:""Orphanet:441447""|efo:""Orphanet:98991""|efo:""Orphanet:98993""|efo:""Orphanet:98994""|dip:DIP-96N|panther:PTHR24416(orthology-group)|ensembl:ENSP00000351209.5"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:9VFikLd4ftRmEyBpY0JHdpHINT09606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P28288	intact:EBI-27055396	intact:EBI-80992|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|ensembl:ENSP00000359233.4|uniprotkb:D3DT46	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001116146.1|refseq:NP_002849.1|ensembl:ENSG00000117528.14(gene)|ensembl:ENST00000370214.9(transcript)|go:""GO:0000038""(very long-chain fatty acid metabolic process)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0007031""(peroxisome organization)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0015910""(long-chain fatty acid import into peroxisome)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0042760""(very long-chain fatty acid catabolic process)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0047617""(fatty acyl-CoA hydrolase activity)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:1903512""(phytanic acid metabolic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR050835|mint:P28288|rcsb pdb:8Z0F|rcsb pdb:8Z9X|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798|panther:PTHR11384(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9Y6M7	intact:EBI-27055396	intact:EBI-1044546|uniprotkb:O60350|uniprotkb:Q6AHZ9|uniprotkb:Q9HC88|uniprotkb:Q9UIB9|uniprotkb:A6NIA8|uniprotkb:B2CI53|uniprotkb:B5M451|uniprotkb:B5M452|uniprotkb:B5M453|uniprotkb:B6DY52|uniprotkb:B6DY53|uniprotkb:C9JST9|uniprotkb:B5M449|uniprotkb:D3K174|uniprotkb:D3K175|intact:EBI-10982200|intact:EBI-11577841|ensembl:ENSP00000295736.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:s4a7_human(display_long)|uniprotkb:Sodium bicarbonate cotransporter 2(gene name synonym)|uniprotkb:Sodium bicarbonate cotransporter 2b(gene name synonym)|uniprotkb:Solute carrier family 4 member 7(gene name synonym)|uniprotkb:SLC4A7(gene name)|psi-mi:SLC4A7(display_short)|uniprotkb:BT(gene name synonym)|uniprotkb:NBC2(gene name synonym)|uniprotkb:NBC2B(gene name synonym)|uniprotkb:NBC3(gene name synonym)|uniprotkb:SBC2(gene name synonym)|uniprotkb:SLC4A6(gene name synonym)|uniprotkb:NBCn1(gene name synonym)|uniprotkb:""Electroneutral Na/HCO(3) cotransporter""(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_003606.3|refseq:NP_001245308.1|refseq:NP_001245309.1|refseq:NP_001308032.1|refseq:NP_001308033.1|refseq:NP_001308034.1|refseq:NP_001308035.1|refseq:NP_001308036.1|refseq:NP_001308037.1|refseq:XP_016863017.1|refseq:XP_016863018.1|ensembl:ENSG00000033867.18(gene)|ensembl:ENST00000295736.9(transcript)|go:""GO:0005452""(""solute:inorganic anion antiporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006221""(pyrimidine nucleotide biosynthetic process)|go:""GO:0008509""(monoatomic anion transmembrane transporter activity)|go:""GO:0008510""(""sodium:bicarbonate symporter activity"")|go:""GO:0015701""(bicarbonate transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0032420""(stereocilium)|go:""GO:0051453""(regulation of intracellular pH)|go:""GO:0055085""(transmembrane transport)|go:""GO:0060117""(auditory receptor cell development)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0090383""(phagosome acidification)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|mint:Q9Y6M7|reactome:R-HSA-425381|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9035034|panther:PTHR11453(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:vsq90qG3qxPyZgkoyvS0MPamvOg9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9UEY8	intact:EBI-27055396	intact:EBI-2838698|uniprotkb:Q9UEY7|uniprotkb:O43243|uniprotkb:Q92773|uniprotkb:Q5VU09|uniprotkb:D3DRA8|ensembl:ENSP00000348381.4|intact:EBI-28975834	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:addg_human(display_long)|uniprotkb:ADD3(gene name)|psi-mi:ADD3(display_short)|uniprotkb:ADDL(gene name synonym)|uniprotkb:Adducin-like protein 70(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000148700.15(gene)|ensembl:ENST00000356080.9(transcript)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005938""(cell cortex)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051495""(positive regulation of cytoskeleton organization)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|interpro:IPR051017|mint:Q9UEY8|reactome:R-HSA-5223345|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_001112.2|refseq:NP_001307520.1|refseq:NP_001307521.1|refseq:NP_001307522.1|refseq:NP_001307523.1|refseq:NP_058432.1|refseq:NP_063968.1|efo:""Orphanet:210141""|panther:PTHR10672(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:10ZAHAI90VaVf/xUxFcNVX5cIts9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q969F9	intact:EBI-27055396	intact:EBI-16781620|uniprotkb:A8K6G6|uniprotkb:Q8WTV6|uniprotkb:Q96AP1|uniprotkb:Q96MR3|uniprotkb:Q9H608|ensembl:ENSP00000296051.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:hps3_human(display_long)|uniprotkb:Hermansky-Pudlak syndrome 3 protein(gene name synonym)|uniprotkb:HPS3(gene name)|psi-mi:HPS3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.47	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:231512""|ensembl:ENSG00000163755.9(gene)|ensembl:ENST00000296051.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0031084""(BLOC-2 complex)|go:""GO:0046907""(intracellular transport)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:1903232""(melanosome assembly)|interpro:IPR017216(BLOC-2 complex, Hps3 subunit)|interpro:IPR029437|interpro:IPR029438|mint:Q969F9|refseq:NP_001295187.1|refseq:NP_115759.2|panther:PTHR28633(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:v6pL0ap1hoLI7VbA0j1M2ZEwlgw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q14126	intact:EBI-27055396	intact:EBI-2556545|uniprotkb:Q4KKU6|ensembl:ENSP00000261590.8	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:dsg2_human(display_long)|uniprotkb:CDHF5(gene name synonym)|uniprotkb:HDGC(gene name synonym)|uniprotkb:Cadherin family member 5(gene name synonym)|uniprotkb:DSG2(gene name)|psi-mi:DSG2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"dip:DIP-46250N|efo:""Orphanet:154""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|ensembl:ENSG00000046604.15(gene)|ensembl:ENST00000261590.13(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0002934""(desmosome organization)|go:""GO:0003165""(Purkinje myocyte development)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0009986""(cell surface)|go:""GO:0014704""(intercalated disc)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0030054""(cell junction)|go:""GO:0030057""(desmosome)|go:""GO:0032570""(response to progesterone)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0086073""(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:""GO:0086083""(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR050971|mint:Q14126|rcsb pdb:2YQG|rcsb pdb:5ERD|rcsb pdb:5J5J|rcsb pdb:6QNT|rcsb pdb:6QNU|rcsb pdb:6SIT|rcsb pdb:7A7D|rcsb pdb:7AGF|rcsb pdb:7AGG|rcsb pdb:8QJX|rcsb pdb:8QJY|rcsb pdb:8QK3|reactome:R-HSA-351906|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:NP_001934.2|panther:PTHR24025(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:LCSf84WRgh5lTrze5IEzFaBeuEc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q15758	intact:EBI-27055396	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|ensembl:ENSG00000105281.13(gene)|ensembl:ENST00000542575.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0006868""(glutamine transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010585""(glutamine secretion)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015183""(L-aspartate transmembrane transporter activity)|go:""GO:0015186""(L-glutamine transmembrane transporter activity)|go:""GO:0015194""(L-serine transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0016020""(membrane)|go:""GO:0022834""(ligand-gated channel activity)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070207""(protein homotrimerization)|go:""GO:0140009""(L-aspartate import across plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1903803""(L-glutamine import across plasma membrane)|interpro:IPR001991(""Sodium:dicarboxylate symporter"")|interpro:IPR018107|interpro:IPR036458|interpro:IPR050746|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|rcsb pdb:7BCQ|rcsb pdb:7BCS|rcsb pdb:7BCT|rcsb pdb:8OUD|rcsb pdb:8OUH|rcsb pdb:8OUJ|rcsb pdb:8QRO|rcsb pdb:8QRP|rcsb pdb:8QRQ|rcsb pdb:8QRR|rcsb pdb:8QRS|rcsb pdb:8QRU|rcsb pdb:8QRV|rcsb pdb:8QRW|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|panther:PTHR11958(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P50851	intact:EBI-27055396	intact:EBI-1052167|uniprotkb:Q9H2U3|uniprotkb:Q9H2U4|uniprotkb:Q8NFQ0|uniprotkb:Q4W5J4|uniprotkb:Q4W5L6|ensembl:ENSP00000349629.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lrba_human(display_long)|uniprotkb:CDC4-like protein(gene name synonym)|uniprotkb:Beige-like protein(gene name synonym)|uniprotkb:LRBA(gene name)|psi-mi:LRBA(display_short)|uniprotkb:BGL(gene name synonym)|uniprotkb:CDC4L(gene name synonym)|uniprotkb:LBA(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"dip:DIP-50531N|ensembl:ENSG00000198589.15(gene)|ensembl:ENST00000357115.9(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0034497""(protein localization to phagophore assembly site)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR010508(Protein of unknown function DUF1088)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|interpro:IPR046851|interpro:IPR046852|interpro:IPR050865|mint:P50851|rcsb pdb:1T77|refseq:NP_001186211.2|refseq:NP_006717.2|refseq:XP_011530736.1|efo:""Orphanet:445018""|panther:PTHR13743(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:FSUTaFKy63UUratp7X29LN/f1F49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9Y2U8	intact:EBI-27055396	intact:EBI-2561428|uniprotkb:Q9NT47|uniprotkb:Q9NYA5|ensembl:ENSP00000308369.2|intact:EBI-40264392	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:man1_human(display_long)|uniprotkb:MAN1(gene name synonym)|uniprotkb:LEM domain-containing protein 3(gene name synonym)|uniprotkb:LEMD3(gene name)|psi-mi:LEMD3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000174106.3(gene)|ensembl:ENST00000308330.3(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0016020""(membrane)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032926""(negative regulation of activin receptor signaling pathway)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018996|interpro:IPR034394|interpro:IPR035979|interpro:IPR041885|interpro:IPR052277|mint:Q9Y2U8|rcsb pdb:2CH0|rcsb pdb:5ZOJ|rcsb pdb:5ZOK|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001161086.1|refseq:NP_055134.2|efo:""Orphanet:166119""|efo:""Orphanet:1879""|efo:""Orphanet:94063""|panther:PTHR48036(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:8AILzxAZLbxCAzlJ7oPg9WybOmY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P35611	intact:EBI-27055396	intact:EBI-2809187|uniprotkb:Q16156|uniprotkb:Q14729|uniprotkb:A2A3P0|uniprotkb:Q13734|uniprotkb:Q9UJB6|uniprotkb:D3DVR3|uniprotkb:D3DVR4|uniprotkb:D3DVR5|uniprotkb:Q86XM2|ensembl:ENSP00000381197.1|uniprotkb:B4DI79|uniprotkb:A2A3N8|intact:EBI-28966889	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:adda_human(display_long)|uniprotkb:ADD1(gene name)|psi-mi:ADD1(display_short)|uniprotkb:ADDA(gene name synonym)|uniprotkb:Erythrocyte adducin subunit alpha(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001273574.1|refseq:XP_005247994.1|refseq:NP_001110.2|refseq:NP_054908.2|refseq:NP_054909.2|refseq:NP_789771.1|ensembl:ENSG00000087274.19(gene)|ensembl:ENST00000398129.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016604""(nuclear body)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030507""(spectrin binding)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:1903142""(positive regulation of establishment of endothelial barrier)|go:""GO:1903393""(positive regulation of adherens junction organization)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|interpro:IPR051017|mint:P35611|reactome:R-HSA-264870|reactome:R-HSA-381038|reactome:R-HSA-5223345|refseq:XP_016863193.1|refseq:XP_016863195.1|refseq:XP_016863196.1|refseq:XP_016863197.1|refseq:XP_016863198.1|refseq:XP_016863199.1|panther:PTHR10672(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:aXiCTFAzsmSxxV4OAr22SDyjAxI9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P14923	intact:EBI-27055396	intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113.5|ensembl:ENSP00000377507.1|ensembl:ENSP00000377508.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:158687""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:34217""|ensembl:ENSG00000173801.17(gene)|ensembl:ENST00000310706.9(transcript)|ensembl:ENST00000393930.5(transcript)|ensembl:ENST00000393931.8(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0002159""(desmosome assembly)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0014704""(intercalated disc)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030018""(Z disc)|go:""GO:0030057""(desmosome)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0043588""(skin development)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050982""(detection of mechanical stimulus)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071603""(endothelial cell-cell adhesion)|go:""GO:0071665""(gamma-catenin-TCF7L2 complex)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0086073""(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:""GO:0086083""(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0106006""(cytoskeletal protein-membrane anchor activity)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9833576|refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_016880079.1|dip:DIP-36235N|panther:PTHR45976(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8TAA9	intact:EBI-27055396	intact:EBI-682393|uniprotkb:Q86WG8|uniprotkb:Q8N559|uniprotkb:Q5T1D3|uniprotkb:Q5T1D4|ensembl:ENSP00000310800.3|ensembl:ENSP00000347672.2|ensembl:ENSP00000358522.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:vang1_human(display_long)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Strabismus 2(gene name synonym)|uniprotkb:Loop-tail protein 2 homolog(gene name synonym)|uniprotkb:VANGL1(gene name)|psi-mi:VANGL1(display_short)|uniprotkb:STB2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:3027""|ensembl:ENSG00000173218.15(gene)|ensembl:ENST00000310260.7(transcript)|ensembl:ENST00000355485.7(transcript)|ensembl:ENST00000369509.1(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0043473""(pigmentation)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0120197""(mucociliary clearance)|interpro:IPR009539(Strabismus)|mint:Q8TAA9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001165882.1|refseq:NP_001165883.1|refseq:NP_620409.1|panther:PTHR20886(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:TRLqwMf+W5eZcgW8gT5S1zM9VzU9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P51798	intact:EBI-27055396	intact:EBI-4402346|uniprotkb:A6NEJ7|uniprotkb:A8K5T9|uniprotkb:Q9NYX5|uniprotkb:A8K7X1|uniprotkb:B3KPN3|uniprotkb:E9PDB9|ensembl:ENSP00000372193.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:clcn7_human(display_long)|uniprotkb:CLCN7(gene name)|psi-mi:CLCN7(display_short)|uniprotkb:Chloride channel protein 7(gene name synonym)|uniprotkb:Chloride channel 7 alpha subunit(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000103249.19(gene)|ensembl:ENST00000382745.9(transcript)|go:""GO:0005247""(voltage-gated chloride channel activity)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0015108""(chloride transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0016020""(membrane)|go:""GO:0030321""(transepithelial chloride transport)|go:""GO:0034707""(chloride channel complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002249(Chloride channel CLC-7)|interpro:IPR014743(Chloride channel, core)|interpro:IPR046342|interpro:IPR051280|mint:P51798|rcsb pdb:7BXU|rcsb pdb:7CQ5|rcsb pdb:7CQ6|rcsb pdb:7CQ7|rcsb pdb:7JM7|rcsb pdb:8HVT|reactome:R-HSA-2672351|refseq:NP_001107803.1|refseq:NP_001278.1|efo:""Orphanet:210110""|efo:""Orphanet:53""|efo:""Orphanet:667""|panther:PTHR11689(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:ze820JsKN1GtxH/lcPnPWN78k1I9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9NNW5	intact:EBI-27055396	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:wdr6_human(display_long)|uniprotkb:WD repeat-containing protein 6(gene name synonym)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_060501.3|panther:PTHR14344(orthology-group)|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252.19(gene)|ensembl:ENST00000608424.6(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002130""(wobble position ribose methylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0030488""(tRNA methylation)|go:""GO:0070314""(G1 to G0 transition)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR051973|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P13639	intact:EBI-27055396	intact:EBI-352560|uniprotkb:A0A384N6H1|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000167658.16(gene)|ensembl:ENST00000309311.7(transcript)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0016235""(aggresome)|go:""GO:0019901""(protein kinase binding)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043022""(ribosome binding)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:8XSX|rcsb pdb:8Y0W|rcsb pdb:8Y0X|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725|refseq:NP_001952.1|efo:""Orphanet:101112""|panther:PTHR42908(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q02952	intact:EBI-27055396	intact:EBI-2562430|intact:EBI-2680946|uniprotkb:O00310|uniprotkb:O00498|uniprotkb:Q4LE68|uniprotkb:Q5SZ80|uniprotkb:Q5TGN1|uniprotkb:Q68D82|uniprotkb:Q99970|ensembl:ENSP00000253332.1|ensembl:ENSP00000384537.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:aka12_human(display_long)|uniprotkb:AKAP12(gene name)|psi-mi:AKAP12(display_short)|uniprotkb:AKAP250(gene name synonym)|uniprotkb:A-kinase anchor protein 250 kDa(gene name synonym)|uniprotkb:Gravin(gene name synonym)|uniprotkb:Myasthenia gravis autoantigen(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_005091.2|refseq:NP_653080.1|ensembl:ENSG00000131016.17(gene)|ensembl:ENST00000253332.5(transcript)|ensembl:ENST00000402676.7(transcript)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0010738""(regulation of protein kinase A signaling)|go:""GO:0010739""(positive regulation of protein kinase A signaling)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0035733""(hepatic stellate cell activation)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0051018""(protein kinase A binding)|go:""GO:0051602""(response to electrical stimulus)|go:""GO:0051770""(obsolete positive regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0061870""(positive regulation of hepatic stellate cell migration)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0090036""(regulation of protein kinase C signaling)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:1900143""(positive regulation of oligodendrocyte apoptotic process)|interpro:IPR001573(Protein kinase A anchoring region)|interpro:IPR018459|interpro:IPR028540|mint:Q02952|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:XP_005267292.1|refseq:XP_016867006.1|panther:PTHR23209(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:vx4mziqb4PDChwfwSzb7mPrCn4w9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q7Z2W4	intact:EBI-27055396	intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_064504.2|refseq:NP_078901.3|dip:DIP-37896N|ensembl:ENSG00000105939.14(gene)|ensembl:ENST00000242351.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0009615""(response to virus)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0061014""(positive regulation of mRNA catabolic process)|go:""GO:1900246""(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|interpro:IPR051712|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|rcsb pdb:7KZH|rcsb pdb:7TGQ|reactome:R-HSA-6802952|panther:PTHR45740(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P51149	intact:EBI-27055396	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062.3|ensembl:ENSP00000501618.1|ensembl:ENSP00000502000.1|ensembl:ENSP00000502088.1|ensembl:ENSP00000502486.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000075785.14(gene)|ensembl:ENST00000265062.8(transcript)|ensembl:ENST00000674589.1(transcript)|ensembl:ENST00000675342.1(transcript)|ensembl:ENST00000675497.1(transcript)|ensembl:ENST00000676214.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0019003""(GDP binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0036466""(synaptic vesicle recycling via endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045453""(bone resorption)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048524""(positive regulation of viral process)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0061724""(lipophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090383""(phagosome acidification)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0097208""(alveolar lamellar body)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099638""(endosome to plasma membrane protein transport)|go:""GO:1903542""(negative regulation of exosomal secretion)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1905366""(negative regulation of intralumenal vesicle formation)|go:""GO:1905394""(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:3LAW|rcsb pdb:6IYB|rcsb pdb:6WCW|rcsb pdb:7F6J|rcsb pdb:8KB8|rcsb pdb:8ZQ3|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|refseq:NP_004628.4|efo:""Orphanet:99936""|dip:DIP-39879N|panther:PTHR47981(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9P0K7	intact:EBI-27055396	intact:EBI-1023749|uniprotkb:Q6V1W9|uniprotkb:Q7Z5I4|uniprotkb:Q7Z733|uniprotkb:Q9P2L2|uniprotkb:Q9Y3T5|uniprotkb:E9PED3|intact:EBI-2555698|ensembl:ENSP00000265109.3|ensembl:ENSP00000388725.2|ensembl:ENSP00000422942.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:rai14_human(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:RAI14(gene name)|psi-mi:RAI14(display_short)|uniprotkb:KIAA1334(gene name synonym)|uniprotkb:NORPEG(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.47	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001138992.1|refseq:NP_001138993.1|refseq:NP_001138994.1|refseq:NP_001138995.1|refseq:NP_001138997.1|refseq:NP_056392.2|refseq:XP_011512319.1|refseq:XP_011512320.1|refseq:XP_011512321.1|refseq:XP_011512322.1|refseq:XP_011512323.1|refseq:XP_011512324.1|refseq:XP_006714532.1|refseq:XP_016864824.1|ensembl:ENSG00000039560.14(gene)|ensembl:ENST00000265109.8(transcript)|ensembl:ENST00000428746.6(transcript)|ensembl:ENST00000503673.5(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030154""(cell differentiation)|go:""GO:0070161""(anchoring junction)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR042420|mint:Q9P0K7|panther:PTHR24129(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:m5hQYx6HEi9QEAey1UiNpeAp6tw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O60716	intact:EBI-27055396	intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	"psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:""p120(cas)""(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000198561.16(gene)|ensembl:ENST00000399050.10(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009986""(cell surface)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016342""(catenin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030426""(growth cone)|go:""GO:0030496""(midbody)|go:""GO:0043197""(dendritic spine)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045296""(cadherin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098831""(presynaptic active zone cytoplasmic component)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0150107""(positive regulation of protein localization to cell-cell junction)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9833576|refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|efo:""Orphanet:1997""|dip:DIP-33850N|panther:PTHR10372(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:HgMvbcDKedE291TIvIOqLFT3srw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q14160	intact:EBI-27055396	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000349486.2|ensembl:ENSP00000484041.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_056171.3|refseq:NP_874365.3|ensembl:ENSG00000180900.20(gene)|ensembl:ENSG00000274287.4(gene)|ensembl:ENST00000356994.7(transcript)|ensembl:ENST00000612204.4(transcript)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001843""(neural tube closure)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016080""(synaptic vesicle targeting)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0034750""(Scrib-APC-beta-catenin complex)|go:""GO:0035089""(establishment of apical/basal cell polarity)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042060""(wound healing)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043615""(astrocyte cell migration)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060561""(apoptotic process involved in morphogenesis)|go:""GO:0060603""(mammary gland duct morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098793""(presynapse)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098968""(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099147""(extrinsic component of postsynaptic density membrane)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|interpro:IPR050614|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|rcsb pdb:7QRS|rcsb pdb:7QRT|rcsb pdb:7QS8|rcsb pdb:7QS9|rcsb pdb:7QSA|rcsb pdb:7QSB|rcsb pdb:7QTO|rcsb pdb:7QTP|rcsb pdb:7QTU|rcsb pdb:8B82|rcsb pdb:8B87|rcsb pdb:8B8O|rcsb pdb:8B9T|rcsb pdb:8BIA|rcsb pdb:8BJ0|rcsb pdb:8CD3|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270|dip:DIP-31259N|panther:PTHR23119(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:xHNrql5wX2JZV+9YxFGM7gm1/CY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q04721	intact:EBI-27055396	intact:EBI-2652733|uniprotkb:Q5T3X7|uniprotkb:Q99734|uniprotkb:Q9H240|ensembl:ENSP00000256646.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:notc2_human(display_long)|uniprotkb:NOTCH2(gene name)|psi-mi:NOTCH2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:261629""|efo:""Orphanet:955""|ensembl:ENSG00000134250.21(gene)|ensembl:ENST00000256646.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001709""(cell fate determination)|go:""GO:0001947""(heart looping)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0002315""(marginal zone B cell differentiation)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0006915""(apoptotic process)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007411""(axon guidance)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009986""(cell surface)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010838""(positive regulation of keratinocyte proliferation)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035622""(intrahepatic bile duct development)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042060""(wound healing)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043011""(myeloid dendritic cell differentiation)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0046849""(bone remodeling)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0060413""(atrial septum morphogenesis)|go:""GO:0060674""(placenta blood vessel development)|go:""GO:0061073""(ciliary body morphogenesis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0072014""(proximal tubule development)|go:""GO:0072015""(podocyte development)|go:""GO:0072104""(glomerular capillary formation)|go:""GO:0072574""(hepatocyte proliferation)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1990705""(cholangiocyte proliferation)|go:""GO:2001204""(regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022336|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:Q04721|rcsb pdb:2OO4|rcsb pdb:5MWB|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-2197563|reactome:R-HSA-2979096|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013695|refseq:NP_001186930.1|refseq:NP_077719.2|ensembl:ENSP00000256646.2|panther:PTHR45836(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:aXdQSGMwNJ7K0tA2kc3rRFysbIc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q12959	intact:EBI-27055396	intact:EBI-357481|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21|ensembl:ENSP00000391732.2|ensembl:ENSP00000407531.1|ensembl:ENSP00000499437.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:199306""|ensembl:ENSG00000075711.21(gene)|ensembl:ENST00000419354.5(transcript)|ensembl:ENST00000448528.6(transcript)|ensembl:ENST00000670935.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001658""(branching involved in ureteric bud morphogenesis)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0001772""(immunological synapse)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0002088""(lens development in camera-type eye)|go:""GO:0004385""(guanylate kinase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0005604""(basement membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007399""(nervous system development)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0014704""(intercalated disc)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030054""(cell junction)|go:""GO:0030432""(peristalsis)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031253""(cell projection membrane)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0031579""(membrane raft organization)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031641""(regulation of myelination)|go:""GO:0033268""(node of Ranvier)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042383""(sarcolemma)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042982""(amyloid precursor protein metabolic process)|go:""GO:0043005""(neuron projection)|go:""GO:0043113""(receptor clustering)|go:""GO:0043219""(lateral loop)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048608""(reproductive structure development)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0048745""(smooth muscle tissue development)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0051660""(establishment of centrosome localization)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060022""(hard palate development)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0097016""(L27 domain binding)|go:""GO:0097025""(MPP7-DLG1-LIN7 complex)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097120""(receptor localization to synapse)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0098915""(membrane repolarization during ventricular cardiac muscle cell action potential)|go:""GO:0098919""(structural constituent of postsynaptic density)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099645""(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:1902305""(regulation of sodium ion transmembrane transport)|go:""GO:1902473""(regulation of protein localization to synapse)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903286""(regulation of potassium ion import)|go:""GO:1903753""(negative regulation of p38MAPK cascade)|go:""GO:1903764""(regulation of potassium ion export across plasma membrane)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313(""Membrane-associated guanylate kinase (MAGUK) scaffold protein"")|interpro:IPR019583|interpro:IPR036034|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036892|interpro:IPR050614|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|rcsb pdb:7PC3|rcsb pdb:8CN1|rcsb pdb:8CN3|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_001277912.1|refseq:NP_004078.2|refseq:XP_005269346.1|refseq:XP_011510804.1|refseq:XP_011510805.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861299.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|panther:PTHR23119(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O00161	intact:EBI-27055396	intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_003816.2|refseq:NP_570710.1|refseq:XP_016878183.1|ensembl:ENSG00000092531.10(gene)|ensembl:ENST00000249647.8(transcript)|go:""GO:0002553""(histamine secretion by mast cell)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006887""(exocytosis)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006903""(vesicle targeting)|go:""GO:0015031""(protein transport)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042581""(specific granule)|go:""GO:0042582""(azurophil granule)|go:""GO:0043005""(neuron projection)|go:""GO:0061025""(membrane fusion)|go:""GO:0070032""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0098793""(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR19305(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8WUY9	intact:EBI-27055396	intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|uniprotkb:B4DUT4|ensembl:ENSP00000265036.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499.13(gene)|ensembl:ENST00000265036.10(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0016477""(cell migration)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0035556""(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|mint:Q8WUY9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|panther:PTHR16206(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q92841	intact:EBI-27055396	intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_006377.2|dip:DIP-29843N|ensembl:ENSG00000100201.23(gene)|ensembl:ENST00000403230.3(transcript)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0002376""(immune system process)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006364""(rRNA processing)|go:""GO:0006396""(RNA processing)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0010586""(miRNA metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051607""(defense response to virus)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2001014""(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR046330|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|panther:PTHR47958(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q7Z3T8	intact:EBI-27055396	intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|uniprotkb:Q5H9U2|ensembl:ENSP00000337159.5|ensembl:ENSP00000423663.1|ensembl:ENSP00000426848.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000039319.17(gene)|ensembl:ENST00000338008.9(transcript)|ensembl:ENST00000505560.5(transcript)|ensembl:ENST00000510158.5(transcript)|go:""GO:0005545""(1-phosphatidylinositol binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0007165""(signal transduction)|go:""GO:0016050""(vesicle organization)|go:""GO:0016197""(endosomal transport)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0031901""(early endosome membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|mint:Q7Z3T8|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_005248689.1|refseq:XP_011542055.1|refseq:XP_016865580.1|refseq:XP_016865581.1|panther:PTHR46319(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O15126	intact:EBI-27055396	intact:EBI-954338|uniprotkb:O43587|uniprotkb:Q96BX1|uniprotkb:Q96QK5|uniprotkb:Q6FG23|ensembl:ENSP00000481022.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:scam1_human(display_long)|uniprotkb:SCAMP1(gene name)|psi-mi:SCAMP1(display_short)|uniprotkb:SCAMP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_004857.4|refseq:NP_001277158.1|ensembl:ENSG00000085365.18(gene)|ensembl:ENST00000621999.5(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0055038""(recycling endosome membrane)|interpro:IPR007273(SCAMP)|mint:O15126|reactome:R-HSA-6798695|panther:PTHR10687(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:Utuf4fnpMHS2yG4zfccdB2enfxI9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9BZH6	intact:EBI-27055396	intact:EBI-2009923|uniprotkb:Q5VWA1|uniprotkb:Q9P2J6|ensembl:ENSP00000263461.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:wdr11_human(display_long)|uniprotkb:WDR11(gene name)|psi-mi:WDR11(display_short)|uniprotkb:KIAA1351(gene name synonym)|uniprotkb:BRWD2(gene name synonym)|uniprotkb:WDR15(gene name synonym)|uniprotkb:Bromodomain and WD repeat-containing protein 2(gene name synonym)|uniprotkb:WD repeat-containing protein 15(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR14593(orthology-group)|efo:""Orphanet:432""|efo:""Orphanet:478""|efo:""Orphanet:95496""|ensembl:ENSG00000120008.16(gene)|ensembl:ENST00000263461.11(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005930""(axoneme)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007507""(heart development)|go:""GO:0008589""(regulation of smoothened signaling pathway)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0036064""(ciliary basal body)|go:""GO:0060271""(cilium assembly)|go:""GO:0060322""(head development)|go:""GO:0099041""(vesicle tethering to Golgi)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR039694|mint:Q9BZH6|rcsb pdb:8XFB|rcsb pdb:8Z9M|reactome:R-HSA-9013407|refseq:NP_060587.8"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:Kl337t8mCHvvkb8oi0z8Ohl72a09606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9BSJ8	intact:EBI-27055396	intact:EBI-355956|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548|ensembl:ENSP00000377612.5|intact:EBI-21360363	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001171725.1|refseq:NP_056107.1|ensembl:ENSG00000139641.13(gene)|ensembl:ENST00000394048.10(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0008429""(phosphatidylethanolamine binding)|go:""GO:0016020""(membrane)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:0120014""(phospholipid transfer activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|interpro:IPR051634|mint:Q9BSJ8|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9845576|dip:DIP-57197N|panther:PTHR45761(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q14677	intact:EBI-27055396	intact:EBI-1171113|uniprotkb:Q8NAF1|uniprotkb:Q96E05|uniprotkb:D3DQJ6|uniprotkb:B7Z6F8|intact:EBI-28971708|ensembl:ENSP00000388340.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:epn4_human(display_long)|uniprotkb:CLINT1(gene name)|psi-mi:CLINT1(display_short)|uniprotkb:ENTH(gene name synonym)|uniprotkb:EPN4(gene name synonym)|uniprotkb:EPNR(gene name synonym)|uniprotkb:KIAA0171(gene name synonym)|uniprotkb:Epsin-4(gene name synonym)|uniprotkb:Epsin-related protein(gene name synonym)|uniprotkb:Enthoprotin(gene name synonym)|uniprotkb:Clathrin-interacting protein localized in the trans-Golgi region(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001182484.1|refseq:NP_001182485.1|refseq:NP_055481.1|panther:PTHR12276(orthology-group)|dip:DIP-45604N|ensembl:ENSG00000113282.14(gene)|ensembl:ENST00000411809.7(transcript)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0016020""(membrane)|go:""GO:0030125""(clathrin vesicle coat)|go:""GO:0030276""(clathrin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q14677|rcsb pdb:1XGW|rcsb pdb:2QY7|rcsb pdb:2V8S|reactome:R-HSA-432722"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:cflzNAWnEQR6zTr4d+hwfy1doC49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P08195	intact:EBI-27055396	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P31943	intact:EBI-27055396	intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168.5|ensembl:ENSP00000377082.4|ensembl:ENSP00000397797.2|ensembl:ENSP00000421695.2|ensembl:ENSP00000424087.2|ensembl:ENSP00000425343.2|ensembl:ENSP00000426518.2|ensembl:ENSP00000429661.2|ensembl:ENSP00000492076.2|ensembl:ENSP00000518308.1|ensembl:ENSP00000518309.1|ensembl:ENSP00000518316.1|ensembl:ENSP00000518317.1|ensembl:ENSP00000518318.1|ensembl:ENSP00000518319.1|ensembl:ENSP00000518321.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:662207""|ensembl:ENSG00000169045.19(gene)|ensembl:ENSG00000284254.4(gene)|ensembl:ENST00000356731.9(transcript)|ensembl:ENST00000393432.9(transcript)|ensembl:ENST00000442819.6(transcript)|ensembl:ENST00000505811.6(transcript)|ensembl:ENST00000513225.6(transcript)|ensembl:ENST00000515158.6(transcript)|ensembl:ENST00000515714.6(transcript)|ensembl:ENST00000521116.6(transcript)|ensembl:ENST00000638505.3(transcript)|ensembl:ENST00000710500.1(transcript)|ensembl:ENST00000710502.1(transcript)|ensembl:ENST00000710510.1(transcript)|ensembl:ENST00000710511.1(transcript)|ensembl:ENST00000710512.1(transcript)|ensembl:ENST00000710513.1(transcript)|ensembl:ENST00000710515.1(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|interpro:IPR050666|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|rcsb pdb:7ZUG|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001244222.1|refseq:NP_005511.1|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1|panther:PTHR13976(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q16625	intact:EBI-27055396	intact:EBI-2903088|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4|ensembl:ENSP00000347379.2|ensembl:ENSP00000379719.2|ensembl:ENSP00000505426.1|ensembl:ENSP00000505541.1|ensembl:ENSP00000506162.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000197822.12(gene)|ensembl:ENST00000355237.6(transcript)|ensembl:ENST00000396442.7(transcript)|ensembl:ENST00000680027.1(transcript)|ensembl:ENST00000681041.1(transcript)|ensembl:ENST00000681586.1(transcript)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010827""(regulation of D-glucose transmembrane transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070160""(tight junction)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:1902463""(protein localization to cell leading edge)|go:""GO:1905605""(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|mint:Q16625|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|refseq:XP_016864402.1|refseq:XP_016864403.1|dip:DIP-42791N|efo:""Orphanet:1229""|panther:PTHR23288(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9H2J7	intact:EBI-27055396	intact:EBI-11343466|uniprotkb:E7ESJ5|uniprotkb:B7Z2P7|uniprotkb:A8K592|uniprotkb:Q9H9F5|ensembl:ENSP00000266682.5|ensembl:ENSP00000505286.1|ensembl:ENSP00000505485.1|ensembl:ENSP00000505789.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:s6a15_human(display_long)|uniprotkb:SLC6A15(gene name)|psi-mi:SLC6A15(display_short)|uniprotkb:B0AT2(gene name synonym)|uniprotkb:NTT73(gene name synonym)|uniprotkb:SBAT1(gene name synonym)|uniprotkb:Sodium- and chloride-dependent neurotransmitter transporter NTT73(gene name synonym)|uniprotkb:Sodium-coupled branched-chain amino-acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 6 member 15(gene name synonym)|uniprotkb:Transporter v7-3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001139807.1|refseq:NP_060527.2|refseq:NP_877499.1|panther:PTHR11616(orthology-group)|ensembl:ENSG00000072041.18(gene)|ensembl:ENST00000266682.10(transcript)|ensembl:ENST00000680963.1(transcript)|ensembl:ENST00000681106.1(transcript)|ensembl:ENST00000681721.1(transcript)|go:""GO:0005295""(""neutral L-amino acid:sodium symporter activity"")|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005326""(neurotransmitter transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015657""(""branched-chain amino acid:sodium symporter activity"")|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015824""(proline transport)|go:""GO:0016020""(membrane)|go:""GO:0035725""(sodium ion transmembrane transport)|interpro:IPR000175(""Sodium:neurotransmitter symporter"")|interpro:IPR002438(""Sodium:neurotransmitter symporter, orphan"")|interpro:IPR037272|interpro:IPR042934|mint:Q9H2J7|reactome:R-HSA-352230|reactome:R-HSA-442660"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:MubTClioe24j6+ldJKeHsmuzg1U9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P0CG47	intact:EBI-27055396	intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697.3|ensembl:ENSP00000379178.1|ensembl:ENSP00000379180.1|ensembl:ENSP00000478771.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:101023""|efo:""Orphanet:155878""|efo:""Orphanet:99771""|efo:""Orphanet:99772""|ensembl:ENSG00000170315.14(gene)|ensembl:ENST00000302182.8(transcript)|ensembl:ENST00000395837.1(transcript)|ensembl:ENST00000395839.5(transcript)|ensembl:ENST00000614404.1(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007141""(male meiosis I)|go:""GO:0007144""(female meiosis I)|go:""GO:0008585""(female gonad development)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019941""(modification-dependent protein catabolic process)|go:""GO:0021888""(hypothalamus gonadotrophin-releasing hormone neuron development)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031386""(protein tag activity)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043523""(regulation of neuron apoptotic process)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0060613""(fat pad development)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:0097009""(energy homeostasis)|go:""GO:1902255""(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:1902527""(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR050158|mint:P0CG47|rcsb pdb:2KHW|rcsb pdb:2MBB|rcsb pdb:2MRO|rcsb pdb:2MSG|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:6XQC|rcsb pdb:6XZ1|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7BU0|rcsb pdb:7CAP|rcsb pdb:7DNI|rcsb pdb:7DNJ|rcsb pdb:7E8I|rcsb pdb:7F7X|rcsb pdb:7JMS|rcsb pdb:7LYC|rcsb pdb:7M2K|rcsb pdb:7MC9|rcsb pdb:7MEY|rcsb pdb:7MYF|rcsb pdb:7MYH|rcsb pdb:7NBB|rcsb pdb:7NPO|rcsb pdb:7OJE|rcsb pdb:7OJX|rcsb pdb:7QO4|rcsb pdb:7QO5|rcsb pdb:7RBR|rcsb pdb:7RMA|rcsb pdb:7UD5|rcsb pdb:7US1|rcsb pdb:7UV5|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:7W3U|rcsb pdb:7W54|rcsb pdb:7XCR|rcsb pdb:7XCT|rcsb pdb:7YQK|rcsb pdb:8A67|rcsb pdb:8BS9|rcsb pdb:8C07|rcsb pdb:8C61|rcsb pdb:8CMR|rcsb pdb:8DMQ|rcsb pdb:8DMS|rcsb pdb:8DU4|rcsb pdb:8EFW|rcsb pdb:8EFX|rcsb pdb:8EHO|rcsb pdb:8G6G|rcsb pdb:8G6H|rcsb pdb:8G6Q|rcsb pdb:8G6S|rcsb pdb:8GRM|rcsb pdb:8H1T|rcsb pdb:8HQY|rcsb pdb:8IC9|rcsb pdb:8ITP|rcsb pdb:8J1P|rcsb pdb:8OYP|rcsb pdb:8Q00|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8TXV|rcsb pdb:8TXW|rcsb pdb:8TXX|rcsb pdb:8V25|rcsb pdb:8V26|rcsb pdb:8V27|rcsb pdb:8V28|rcsb pdb:8W31|rcsb pdb:8WG5|rcsb pdb:8XEP|rcsb pdb:9AVT|rcsb pdb:9AVW|rcsb pdb:9AZJ|rcsb pdb:9B0Z|rcsb pdb:9B12|rcsb pdb:9C5E|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866427|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-909733|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9680350|reactome:R-HSA-9683683|reactome:R-HSA-9692916|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-9725370|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-9755511|reactome:R-HSA-9758274|reactome:R-HSA-9762114|reactome:R-HSA-977225|reactome:R-HSA-9824878|reactome:R-HSA-9828211|reactome:R-HSA-983168|reactome:R-HSA-9833109|reactome:R-HSA-9861718|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|refseq:NP_061828.1|panther:PTHR10666(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q15019	intact:EBI-27055396	intact:EBI-741220|intact:EBI-28986019|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3|ensembl:ENSP00000353157.3|ensembl:ENSP00000375832.2|ensembl:ENSP00000375834.2|ensembl:ENSP00000385172.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001269901.1|refseq:NP_001269902.1|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:NP_001307960.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSG00000168385.18(gene)|ensembl:ENST00000360051.7(transcript)|ensembl:ENST00000391971.7(transcript)|ensembl:ENST00000391973.6(transcript)|ensembl:ENST00000402092.6(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0002036""(regulation of L-glutamate import across plasma membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005886""(plasma membrane)|go:""GO:0005930""(axoneme)|go:""GO:0005940""(septin ring)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008104""(protein localization)|go:""GO:0009986""(cell surface)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0030154""(cell differentiation)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0030496""(midbody)|go:""GO:0031105""(septin complex)|go:""GO:0032153""(cell division site)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042802""(identical protein binding)|go:""GO:0045171""(intercellular bridge)|go:""GO:0045296""(cadherin binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060170""(ciliary membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0061640""(cytoskeleton-dependent cytokinesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097227""(sperm annulus)|go:""GO:0097730""(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|rcsb pdb:7M6J|reactome:R-HSA-5620912|refseq:XP_016859694.1|refseq:XP_016859695.1|dip:DIP-38220N|panther:PTHR18884(orthology-group)"	-	-	crc64:12CCBBE30806F92F	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P05023	intact:EBI-27055396	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|ensembl:ENSP00000295598.5|intact:EBI-10963133	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR43294(orthology-group)|ensembl:ENSG00000163399.16(gene)|ensembl:ENST00000295598.10(transcript)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0005391""(""P-type sodium:potassium-exchanging transporter activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0007231""(osmosensory signaling pathway)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016791""(phosphatase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030315""(T-tubule)|go:""GO:0030424""(axon)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031090""(organelle membrane)|go:""GO:0031402""(sodium ion binding)|go:""GO:0031947""(negative regulation of glucocorticoid biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0045823""(positive regulation of heart contraction)|go:""GO:0045989""(positive regulation of striated muscle contraction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060342""(photoreceptor inner segment membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086009""(membrane repolarization)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903416""(response to glycoside)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990239""(steroid hormone binding)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|interpro:IPR050510|mint:P05023|rcsb pdb:7E1Z|rcsb pdb:7E20|rcsb pdb:7E21|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|efo:""Orphanet:521414""|efo:""Orphanet:564178"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q86X29	intact:EBI-27055396	intact:EBI-1056946|uniprotkb:O00112|uniprotkb:O00426|uniprotkb:Q6ZT80|uniprotkb:Q9UQL3|uniprotkb:E9PHD4|uniprotkb:Q8NBM0|uniprotkb:Q9BT33|uniprotkb:A6NDW3|ensembl:ENSP00000480821.1|intact:EBI-10982122|uniprotkb:B4DKL4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lsr_human(display_long)|uniprotkb:Angulin-1(gene name synonym)|uniprotkb:ILDR3(gene name synonym)|uniprotkb:LSR(gene name)|psi-mi:LSR(display_short)|uniprotkb:LISCH(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_991403.1|refseq:NP_001247418.1|refseq:NP_001247419.1|refseq:NP_057009.3|refseq:NP_991404.1|ensembl:ENSG00000105699.17(gene)|ensembl:ENST00000621372.4(transcript)|go:""GO:0001889""(liver development)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0030054""(cell junction)|go:""GO:0034361""(very-low-density lipoprotein particle)|go:""GO:0034362""(low-density lipoprotein particle)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042627""(chylomicron)|go:""GO:0060856""(establishment of blood-brain barrier)|go:""GO:0061436""(establishment of skin barrier)|go:""GO:0061689""(tricellular tight junction)|go:""GO:0061833""(protein localization to tricellular tight junction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070160""(tight junction)|go:""GO:1904274""(tricellular tight junction assembly)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008664(LISCH7)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR051874|mint:Q86X29|reactome:R-HSA-8964038|reactome:R-HSA-8964046|panther:PTHR15923(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:jCmNdVxzNBHEpWjKNqyq5e6yEjs9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q92597	intact:EBI-27055396	intact:EBI-716486|uniprotkb:O15207|uniprotkb:Q9NYR6|uniprotkb:Q9UK29|uniprotkb:Q6IBG2|uniprotkb:B3KR80|uniprotkb:B7Z446|ensembl:ENSP00000319977.8|ensembl:ENSP00000404854.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ndrg1_human(display_long)|uniprotkb:N-myc downstream-regulated gene 1 protein(gene name synonym)|uniprotkb:Differentiation-related gene 1 protein(gene name synonym)|uniprotkb:Reducing agents and tunicamycin-responsive protein(gene name synonym)|uniprotkb:Nickel-specific induction protein Cap43(gene name synonym)|uniprotkb:Rit42(gene name synonym)|uniprotkb:NDRG1(gene name)|psi-mi:NDRG1(display_short)|uniprotkb:CAP43(gene name synonym)|uniprotkb:DRG1(gene name synonym)|uniprotkb:RTP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000104419.17(gene)|ensembl:ENST00000323851.13(transcript)|ensembl:ENST00000414097.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007165""(signal transduction)|go:""GO:0008017""(microtubule binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010038""(response to metal ion)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032287""(peripheral nervous system myelin maintenance)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045576""(mast cell activation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|interpro:IPR004142(Ndr)|interpro:IPR029058|mint:Q92597|rcsb pdb:6ZMM|reactome:R-HSA-6803205|refseq:NP_001128714.1|refseq:NP_001245361.1|refseq:NP_001245362.1|refseq:NP_006087.2|efo:""Orphanet:99950""|panther:PTHR11034(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:zeyNRbcgqPcHXkqwE42s1e9uEqI9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P05556	intact:EBI-27055396	intact:EBI-703066|intact:EBI-4289597|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5|ensembl:ENSP00000303351.3|ensembl:ENSP00000379350.2|ensembl:ENSP00000398029.2|ensembl:ENSP00000404546.3|ensembl:ENSP00000502882.1|ensembl:ENSP00000503546.1|ensembl:ENSP00000503916.1|ensembl:ENSP00000504205.1|ensembl:ENSP00000504444.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|ensembl:ENSG00000150093.20(gene)|ensembl:ENST00000302278.8(transcript)|ensembl:ENST00000396033.6(transcript)|ensembl:ENST00000417122.7(transcript)|ensembl:ENST00000437302.6(transcript)|ensembl:ENST00000677999.1(transcript)|ensembl:ENST00000678701.1(transcript)|ensembl:ENST00000678943.1(transcript)|ensembl:ENST00000678952.1(transcript)|dip:DIP-312N|ensembl:ENST00000678989.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001726""(ruffle)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002020""(protease binding)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006968""(cellular defense response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007517""(muscle organ development)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008305""(integrin complex)|go:""GO:0008354""(germ cell migration)|go:""GO:0008542""(visual learning)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010710""(regulation of collagen catabolic process)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0014704""(intercalated disc)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030175""(filopodium)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031623""(receptor internalization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0033631""(cell-cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034665""(integrin alpha1-beta1 complex)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0034667""(integrin alpha3-beta1 complex)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0034674""(integrin alpha5-beta1 complex)|go:""GO:0034675""(integrin alpha6-beta1 complex)|go:""GO:0034677""(integrin alpha7-beta1 complex)|go:""GO:0034678""(integrin alpha8-beta1 complex)|go:""GO:0034679""(integrin alpha9-beta1 complex)|go:""GO:0034680""(integrin alpha10-beta1 complex)|go:""GO:0034681""(integrin alpha11-beta1 complex)|go:""GO:0034682""(integrin alphav-beta1 complex)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043197""(dendritic spine)|go:""GO:0043235""(receptor complex)|go:""GO:0043236""(laminin binding)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045743""(positive regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048626""(myoblast fate specification)|go:""GO:0048675""(axon extension)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051951""(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0055037""(recycling endosome)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060912""(cardiac cell fate specification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097386""(glial cell projection)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150053""(cerebellar climbing fiber to Purkinje cell synapse)|go:""GO:0150103""(reactive gliosis)|go:""GO:1900748""(positive regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901979""(regulation of inward rectifier potassium channel activity)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905806""(regulation of synapse pruning)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|rcsb pdb:7CEB|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEC|rcsb pdb:7NWL|rcsb pdb:7NXD|rcsb pdb:8RPQ|rcsb pdb:9CKV|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9634597|reactome:R-HSA-9679191|reactome:R-HSA-9725554|reactome:R-HSA-9830674|reactome:R-HSA-9860927|panther:PTHR10082(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q14254	intact:EBI-27055396	intact:EBI-348613|ensembl:ENSP00000378368.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:flot2_human(display_long)|uniprotkb:FLOT2(gene name)|psi-mi:FLOT2(display_short)|uniprotkb:ESA1(gene name synonym)|uniprotkb:M17S1(gene name synonym)|uniprotkb:Epidermal surface antigen(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.47	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_004466.2|ensembl:ENSG00000132589.16(gene)|ensembl:ENST00000394908.9(transcript)|go:""GO:0001931""(uropod)|go:""GO:0002020""(protease binding)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0008544""(epidermis development)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016600""(flotillin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031982""(vesicle)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0044860""(protein localization to plasma membrane raft)|go:""GO:0045661""(regulation of myoblast differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098937""(anterograde dendritic transport)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1902992""(negative regulation of amyloid precursor protein catabolic process)|go:""GO:1903905""(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:Q14254|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9696264|reactome:R-HSA-9696273|refseq:XP_016879883.1|refseq:XP_016879884.1|panther:PTHR13806(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:P9htlLzTYk+eDKKesqCEPe/1BJA9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P22087	intact:EBI-27055396	intact:EBI-358318|uniprotkb:O75259|uniprotkb:Q6IAT5|uniprotkb:Q9UPI6|uniprotkb:B5BUE8|ensembl:ENSP00000221801.2|ensembl:ENSP00000487390.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:fbrl_human(display_long)|uniprotkb:FBL(gene name)|psi-mi:FBL(display_short)|uniprotkb:FIB1(gene name synonym)|uniprotkb:FLRN(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:34 kDa nucleolar scleroderma antigen(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR10335(orthology-group)|refseq:NP_001427.2|ensembl:ENSG00000105202.9(gene)|ensembl:ENSG00000280548.4(gene)|ensembl:ENST00000221801.8(transcript)|ensembl:ENST00000625241.3(transcript)|go:""GO:0000494""(""box C/D sno(s)RNA 3'-end processing"")|go:""GO:0001094""(TFIID-class transcription factor complex binding)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001650""(fibrillar center)|go:""GO:0001652""(granular component)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006364""(rRNA processing)|go:""GO:0008649""(rRNA methyltransferase activity)|go:""GO:0015030""(Cajal body)|go:""GO:0016020""(membrane)|go:""GO:0031167""(rRNA methylation)|go:""GO:0031428""(box C/D methylation guide snoRNP complex)|go:""GO:0032040""(small-subunit processome)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0048254""(snoRNA localization)|go:""GO:0051117""(ATPase binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0180021""(U6 snRNA 2'-O-ribose methyltransferase activity)|go:""GO:1990259""(histone H2A Q104 methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P22087|rcsb pdb:2IPX|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|rcsb pdb:7SE6|rcsb pdb:7SE7|rcsb pdb:7SE8|rcsb pdb:7SE9|rcsb pdb:7SEA|rcsb pdb:7SEB|rcsb pdb:7SEC|rcsb pdb:7SED|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-27569N"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:8m8FDRSxGNKNXpJMcWWbcHL3uss9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P62136	intact:EBI-27055396	intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR11668(orthology-group)|refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|ensembl:ENSG00000172531.16(gene)|ensembl:ENST00000376745.9(transcript)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005977""(glycogen metabolic process)|go:""GO:0005981""(regulation of glycogen catabolic process)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0016311""(dephosphorylation)|go:""GO:0016791""(phosphatase activity)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0030324""(lung development)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0042587""(glycogen granule)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0043153""(entrainment of circadian clock by photoperiod)|go:""GO:0043197""(dendritic spine)|go:""GO:0043204""(perikaryon)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|rcsb pdb:6ALZ|go:""GO:0043558""(regulation of translational initiation in response to stress)|go:""GO:0045725""(positive regulation of glycogen biosynthetic process)|go:""GO:0046914""(transition metal ion binding)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0051301""(cell division)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|go:""GO:2001241""(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186(""Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase"")|interpro:IPR029052|interpro:IPR031675|interpro:IPR050341|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|rcsb pdb:7QFB|rcsb pdb:7QM2|rcsb pdb:7T0Y|rcsb pdb:7TVF|rcsb pdb:7TXH|rcsb pdb:7UPI|rcsb pdb:8DWK|rcsb pdb:8DWL|rcsb pdb:8SW5|rcsb pdb:8SW6|rcsb pdb:8U5G|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|reactome:R-HSA-9828806|dip:DIP-221N|dip:DIP-38195N"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q86W92	intact:EBI-27055396	intact:EBI-1045582|uniprotkb:O75336|uniprotkb:Q86X70|uniprotkb:Q9NY03|uniprotkb:Q9ULJ0|ensembl:ENSP00000314724.8	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lipb1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1(gene name synonym)|uniprotkb:PPFIBP1(gene name)|psi-mi:PPFIBP1(display_short)|uniprotkb:KIAA1230(gene name synonym)|uniprotkb:hSGT2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001185844.1|refseq:NP_001185845.1|refseq:NP_003613.3|refseq:NP_803193.2|dip:DIP-42195N|ensembl:ENSG00000110841.14(gene)|ensembl:ENST00000318304.12(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0048786""(presynaptic active zone)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q86W92|reactome:R-HSA-388844|reactome:R-HSA-9725370|panther:PTHR12587(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:PIoFJHaX4lvBJ0EYcascPgJP8bI9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O95721	intact:EBI-27055396	intact:EBI-490676|ensembl:ENSP00000215730.6	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:snp29_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-29(gene name synonym)|uniprotkb:Soluble 29 kDa NSF attachment protein(gene name synonym)|uniprotkb:SNAP29(gene name)|psi-mi:SNAP29(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000099940.12(gene)|ensembl:ENST00000215730.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005776""(autophagosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006903""(vesicle targeting)|go:""GO:0015031""(protein transport)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0016240""(autophagosome membrane docking)|go:""GO:0019905""(syntaxin binding)|go:""GO:0020018""(ciliary pocket membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0061025""(membrane fusion)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098793""(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|mint:O95721|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-6798695|reactome:R-HSA-6811438|refseq:NP_004773.1|efo:""Orphanet:66631""|dip:DIP-56475N|panther:PTHR19305(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:4HyjERPnEDdBgiGt70N9oyrMN1k9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q658P3	intact:EBI-27055396	intact:EBI-3933105|uniprotkb:Q86SF6|uniprotkb:Q9NVB5|uniprotkb:A8K6E3|uniprotkb:Q8TF03|uniprotkb:Q8TDP3|uniprotkb:Q4VBR2|uniprotkb:Q8NEW6|uniprotkb:Q53SQ8|uniprotkb:Q7Z389|uniprotkb:Q4ZG36|ensembl:ENSP00000376818.2|ensembl:ENSP00000376819.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:stea3_human(display_long)|uniprotkb:STEAP3(gene name)|psi-mi:STEAP3(display_short)|uniprotkb:TSAP6(gene name synonym)|uniprotkb:Dudulin-2(gene name synonym)|uniprotkb:Six-transmembrane epithelial antigen of prostate 3(gene name synonym)|uniprotkb:Tumor suppressor-activated pathway protein 6(gene name synonym)|uniprotkb:pHyde(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000115107.20(gene)|ensembl:ENST00000393106.6(transcript)|ensembl:ENST00000393107.2(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005886""(plasma membrane)|go:""GO:0006826""(iron ion transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0008823""(""cupric reductase (NADH) activity"")|go:""GO:0009306""(protein secretion)|go:""GO:0010008""(endosome membrane)|go:""GO:0015677""(copper ion import)|go:""GO:0020037""(heme binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0052851""(""ferric-chelate reductase (NADPH) activity"")|go:""GO:0071949""(FAD binding)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR028939|interpro:IPR036291|interpro:IPR051267|mint:Q658P3|rcsb pdb:2VNS|rcsb pdb:2VQ3|reactome:R-HSA-6803204|reactome:R-HSA-9013148|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9035034|reactome:R-HSA-917977|refseq:NP_001008410.1|refseq:NP_060704.2|refseq:NP_619543.2|refseq:NP_878919.2|refseq:XP_006712677.1|refseq:XP_006712678.1|refseq:XP_011509705.1|efo:""Orphanet:300298""|panther:PTHR14239(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:fZmXHidOHx0fIw1WYbsyliQcZVA9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q13596	intact:EBI-27055396	intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528.15(gene)|ensembl:ENST00000559844.6(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990460""(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|interpro:IPR036871|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|rcsb pdb:8A1G|rcsb pdb:8ABQ|rcsb pdb:8AFZ|dip:DIP-398N|panther:PTHR10555(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P29966	intact:EBI-27055396	intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_002347.5|ensembl:ENSG00000277443.3(gene)|ensembl:ENST00000612661.2(transcript)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006915""(apoptotic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007015""(actin filament organization)|go:""GO:0007417""(central nervous system development)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0021915""(neural tube development)|go:""GO:0022008""(neurogenesis)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042585""(germinal vesicle)|go:""GO:0042802""(identical protein binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997|panther:PTHR14353(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P98172	intact:EBI-27055396	intact:EBI-538287|uniprotkb:D3DVU0|ensembl:ENSP00000204961.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:efnb1_human(display_long)|uniprotkb:EPH-related receptor tyrosine kinase ligand 2(gene name synonym)|uniprotkb:EFL3(gene name synonym)|uniprotkb:EFNB1(gene name)|psi-mi:EFNB1(display_short)|uniprotkb:EFL-3(gene name synonym)|uniprotkb:EPLG2(gene name synonym)|uniprotkb:LERK2(gene name synonym)|uniprotkb:ELK ligand(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR11304(orthology-group)|ensembl:ENSG00000090776.6(gene)|ensembl:ENST00000204961.5(transcript)|go:""GO:0001755""(neural crest cell migration)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007411""(axon guidance)|go:""GO:0009880""(embryonic pattern specification)|go:""GO:0009986""(cell surface)|go:""GO:0031295""(T cell costimulation)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P98172|rcsb pdb:6THG|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|refseq:NP_004420.1|efo:""Orphanet:1520"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:s9RYPWXKQ2QMzvfGluiliH3YC3s9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q96AC1	intact:EBI-27055396	intact:EBI-4399465|uniprotkb:Q14840|uniprotkb:Q86TY7|uniprotkb:B5TJY2|ensembl:ENSP00000340391.3|ensembl:ENSP00000378993.2|intact:EBI-21355423	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ferm2_human(display_long)|uniprotkb:FERMT2(gene name)|psi-mi:FERMT2(display_short)|uniprotkb:KIND2(gene name synonym)|uniprotkb:MIG2(gene name synonym)|uniprotkb:PLEKHC1(gene name synonym)|uniprotkb:Kindlin-2(gene name synonym)|uniprotkb:Mitogen-inducible gene 2 protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.47	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001128471.1|refseq:NP_001128472.1|refseq:NP_006823.1|ensembl:ENSG00000073712.15(gene)|ensembl:ENST00000341590.8(transcript)|ensembl:ENST00000395631.6(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031674""(I band)|go:""GO:0033622""(integrin activation)|go:""GO:0033625""(positive regulation of integrin activation)|go:""GO:0034334""(adherens junction maintenance)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046332""(SMAD binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0051015""(actin filament binding)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060173""(limb development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902414""(protein localization to cell junction)|go:""GO:1902462""(positive regulation of mesenchymal stem cell proliferation)|go:""GO:1903691""(positive regulation of wound healing, spreading of epidermal cells)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR037837|interpro:IPR037843|interpro:IPR040790|mint:Q96AC1|rcsb pdb:2LGX|rcsb pdb:2LKO|rcsb pdb:2MSU|rcsb pdb:4F7H|rcsb pdb:6U4N|rcsb pdb:6XTJ|reactome:R-HSA-446353|reactome:R-HSA-9013149|reactome:R-HSA-9013423|panther:PTHR16160(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:nmlzKrHEw/aEw6C8i9+G/80jbuE9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O14964	intact:EBI-27055396	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201.4|ensembl:ENSP00000504106.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_004703.1|ensembl:ENSG00000185359.14(gene)|ensembl:ENST00000329138.9(transcript)|ensembl:ENST00000676546.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010324""(membrane invagination)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010642""(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:""GO:0016197""(endosomal transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033565""(ESCRT-0 complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0042176""(regulation of protein catabolic process)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043405""(regulation of MAP kinase activity)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0090148""(membrane fission)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:1903543""(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|dip:DIP-29050N|panther:PTHR46275(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P48029	intact:EBI-27055396	intact:EBI-11334871|uniprotkb:Q66I36|uniprotkb:E9PFC0|uniprotkb:B4DIA3|uniprotkb:Q13032|uniprotkb:B2KY47|ensembl:ENSP00000253122.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:sc6a8_human(display_long)|uniprotkb:SLC6A8(gene name)|psi-mi:SLC6A8(display_short)|uniprotkb:Solute carrier family 6 member 8(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000130821.17(gene)|ensembl:ENST00000253122.10(transcript)|go:""GO:0005308""(creatine transmembrane transporter activity)|go:""GO:0005309""(""creatine:sodium symporter activity"")|go:""GO:0005332""(""gamma-aminobutyric acid:sodium:chloride symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006600""(creatine metabolic process)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0006936""(muscle contraction)|go:""GO:0015881""(creatine transmembrane transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0071705""(nitrogen compound transport)|interpro:IPR000175(""Sodium:neurotransmitter symporter"")|interpro:IPR002984(""Sodium:neurotransmitter symporter, creatine"")|interpro:IPR037272|mint:P48029|reactome:R-HSA-71288|refseq:NP_001136277.1|refseq:NP_001136278.1|refseq:NP_005620.1|panther:PTHR11616(orthology-group)|efo:""Orphanet:52503"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:S4nrtZRMk26EWdnV/Ydet+81k/E9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P20020	intact:EBI-27055396	intact:EBI-5279998|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|ensembl:ENSP00000392043.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000070961.17(gene)|efo:""Orphanet:528084""|ensembl:ENST00000428670.8(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0003056""(regulation of vascular associated smooth muscle contraction)|go:""GO:0005388""(P-type calcium transporter activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0015085""(calcium ion transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030501""(positive regulation of bone mineralization)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042995""(cell projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051481""(negative regulation of cytosolic calcium ion concentration)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098684""(photoreceptor ribbon synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1990034""(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P20020|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9662360|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_011536709.1|refseq:XP_016874847.1|panther:PTHR24093(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P27986	intact:EBI-27055396	intact:EBI-79464|intact:EBI-28974553|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19|ensembl:ENSP00000428056.1|ensembl:ENSP00000429277.1|ensembl:ENSP00000513316.1|ensembl:ENSP00000513333.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:3163""|efo:""Orphanet:33110""|efo:""Orphanet:397596""|panther:PTHR10155(orthology-group)|dip:DIP-119N|ensembl:ENST00000320694.13|ensembl:ENSP00000323512.8|ensembl:ENST00000336483.10|ensembl:ENSP00000338554.5|ensembl:ENSP00000513333.1|ensembl:ENSP00000428056.1|ensembl:ENSP00000429277.1|ensembl:ENST00000523872.1|ensembl:ENSP00000430098.1|ensembl:ENSP00000513316.1|ensembl:ENST00000697461.1|ensembl:ENSP00000513319.1|ensembl:ENST00000697467.1|ensembl:ENSP00000513325.1|interpro:IPR044124|ensembl:ENSG00000145675.16(gene)|ensembl:ENST00000517643.2(transcript)|ensembl:ENST00000521381.6(transcript)|ensembl:ENST00000521657.6(transcript)|ensembl:ENST00000697458.1(transcript)|go:""GO:0001678""(intracellular glucose homeostasis)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0001953""(negative regulation of cell-matrix adhesion)|go:""GO:0002687""(positive regulation of leukocyte migration)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005168""(neurotrophin TRKA receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005942""(phosphatidylinositol 3-kinase complex)|go:""GO:0005943""(phosphatidylinositol 3-kinase complex, class IA)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006955""(immune response)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0019209""(kinase activator activity)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0033120""(positive regulation of RNA splicing)|go:""GO:0034143""(regulation of toll-like receptor 4 signaling pathway)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034644""(cellular response to UV)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035014""(phosphatidylinositol 3-kinase regulator activity)|go:""GO:0035655""(interleukin-18-mediated signaling pathway)|go:""GO:0036312""(phosphatidylinositol 3-kinase regulatory subunit binding)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043125""(ErbB-3 class receptor binding)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0043559""(insulin binding)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0046935""(1-phosphatidylinositol-3-kinase regulator activity)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|rcsb pdb:4L23|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0052742""(phosphatidylinositol kinase activity)|go:""GO:0060396""(growth hormone receptor signaling pathway)|go:""GO:0061470""(T follicular helper cell differentiation)|go:""GO:0097529""(myeloid leukocyte migration)|go:""GO:0120183""(positive regulation of focal adhesion disassembly)|go:""GO:0140767""(enzyme-substrate adaptor activity)|go:""GO:0141038""(phosphatidylinositol 3-kinase activator activity)|go:""GO:1900103""(positive regulation of endoplasmic reticulum unfolded protein response)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1990578""(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:2V1Y|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|rcsb pdb:5SX9|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|rcsb pdb:7CIO|rcsb pdb:7LM2|rcsb pdb:7LQ1|rcsb pdb:7MYN|rcsb pdb:7MYO|rcsb pdb:7PG5|rcsb pdb:7PG6|rcsb pdb:7RNS|rcsb pdb:7TZ7|rcsb pdb:8AM0|rcsb pdb:8DCP|rcsb pdb:8DCX|rcsb pdb:8DD4|rcsb pdb:8DD8|rcsb pdb:8GUB|rcsb pdb:8H36|rcsb pdb:8H37|rcsb pdb:8ILR|rcsb pdb:8ILS|rcsb pdb:8ILV|rcsb pdb:8SBC|rcsb pdb:8SBJ|rcsb pdb:8TDU|rcsb pdb:8TGD|rcsb pdb:8TS7|rcsb pdb:8TS8|rcsb pdb:8TS9|rcsb pdb:8TSA|rcsb pdb:8TSB|rcsb pdb:8TSC|rcsb pdb:8TSD|rcsb pdb:8TU6|rcsb pdb:8V8H|rcsb pdb:8V8I|rcsb pdb:8V8J|rcsb pdb:8V8U|rcsb pdb:8V8V|rcsb pdb:8W9A|rcsb pdb:8W9B|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-180292|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-198203|reactome:R-HSA-201556|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9680350|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9725370|reactome:R-HSA-983695|reactome:R-HSA-9842640|reactome:R-HSA-9842663|refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|refseq:XP_005248599.1|refseq:XP_016865074.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q658Y4	intact:EBI-27055396	intact:EBI-3045545|uniprotkb:Q8TE89|uniprotkb:Q658T5|uniprotkb:B6YY23|ensembl:ENSP00000335082.7	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:f91a1_human(display_long)|uniprotkb:FAM91A1(gene name)|psi-mi:FAM91A1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_659400.2|refseq:NP_001304846.1|refseq:NP_001304847.1|ensembl:ENSG00000176853.16(gene)|ensembl:ENST00000334705.12(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0099041""(vesicle tethering to Golgi)|interpro:IPR028091|interpro:IPR028097|interpro:IPR039199|mint:Q658Y4|rcsb pdb:8JJ9|rcsb pdb:8XFB|rcsb pdb:8Z9M|reactome:R-HSA-9013407|panther:PTHR28441(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:0Fq4tmA02p3P6sxVWlt0RA24hrc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9ULK5	intact:EBI-27055396	intact:EBI-1054279|uniprotkb:Q5T212|uniprotkb:D3DVE9|ensembl:ENSP00000357040.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:vang2_human(display_long)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Strabismus 1(gene name synonym)|uniprotkb:Loop-tail protein 1 homolog(gene name synonym)|uniprotkb:VANGL2(gene name)|psi-mi:VANGL2(display_short)|uniprotkb:KIAA1215(gene name synonym)|uniprotkb:STB1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:563609""|efo:""Orphanet:563612""|ensembl:ENSG00000162738.8(gene)|ensembl:ENST00000368061.3(transcript)|go:""GO:0001736""(establishment of planar polarity)|go:""GO:0001843""(neural tube closure)|go:""GO:0001947""(heart looping)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0035787""(cell migration involved in kidney development)|go:""GO:0036514""(dopaminergic neuron axon guidance)|go:""GO:0036515""(serotonergic neuron axon guidance)|go:""GO:0045176""(apical protein localization)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q9ULK5|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7R2M|rcsb pdb:7R2T|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_065068.1|refseq:XP_005245414.1|refseq:XP_011508106.1|panther:PTHR20886(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:x6JAZMeK90S/m6+oSp/W1tN1Cjc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q15366	intact:EBI-27055396	intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|uniprotkb:B4DXP5|ensembl:ENSP00000408949.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|ensembl:ENSG00000197111.16(gene)|ensembl:ENST00000439930.7(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0039694""(viral RNA genome replication)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045087""(innate immune response)|go:""GO:0050687""(negative regulation of defense response to virus)|go:""GO:0051607""(defense response to virus)|go:""GO:0070062""(extracellular exosome)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0106222""(lncRNA binding)|go:""GO:0140585""(promoter-enhancer loop anchoring activity)|go:""GO:0140588""(chromatin looping)|go:""GO:0160049""(negative regulation of cGAS/STING signaling pathway)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440|reactome:R-HSA-9692916|dip:DIP-58934N|panther:PTHR10288(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P20700	intact:EBI-27055396	intact:EBI-968218|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6|ensembl:ENSP00000261366.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:2514""|efo:""Orphanet:99027""|dip:DIP-34897N|ensembl:ENSG00000113368.12(gene)|ensembl:ENST00000261366.10(transcript)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043274""(phospholipase binding)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|rcsb pdb:3UMN|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:5BNW|rcsb pdb:5VVX|rcsb pdb:7DTG|reactome:R-HSA-1221632|reactome:R-HSA-2559584|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|panther:PTHR45721(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P49757	intact:EBI-27055396	intact:EBI-915016|uniprotkb:Q6NUQ7|uniprotkb:Q86SY1|uniprotkb:Q8WW73|uniprotkb:Q9UBG1|uniprotkb:Q9UEQ4|uniprotkb:Q9UKE8|uniprotkb:Q9UKE9|uniprotkb:Q9UKF0|uniprotkb:Q9UQJ4|uniprotkb:B4E2B1|ensembl:ENSP00000347169.3|ensembl:ENSP00000451300.1|uniprotkb:B1P2N7|uniprotkb:B1P2N8|uniprotkb:B1P2N9|uniprotkb:B1P2N5|uniprotkb:B1P2N6|intact:EBI-28966915	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:numb_human(display_long)|uniprotkb:Protein S171(gene name synonym)|uniprotkb:NUMB(gene name)|psi-mi:NUMB(display_short)|uniprotkb:C14orf41(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001307043.1|refseq:NP_001005743.1|refseq:NP_001005744.1|refseq:NP_001005745.1|refseq:NP_003735.3|ensembl:ENSG00000133961.22(gene)|ensembl:ENST00000355058.7(transcript)|ensembl:ENST00000555238.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005925""(focal adhesion)|go:""GO:0007409""(axonogenesis)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0010008""(endosome membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0021670""(lateral ventricle development)|go:""GO:0021849""(neuroblast division in subventricular zone)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034332""(adherens junction organization)|go:""GO:0045177""(apical part of cell)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P49757|rcsb pdb:5NJJ|rcsb pdb:5NJK|reactome:R-HSA-2122948|reactome:R-HSA-437239|reactome:R-HSA-5610780|reactome:R-HSA-5632684|reactome:R-HSA-9725554|dip:DIP-37981N|panther:PTHR47368(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:X+CHBhp67o6ROnf86RCtXlCAaF49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q15836	intact:EBI-27055396	intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666.6	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_004772.1|ensembl:ENSG00000049245.13(gene)|ensembl:ENST00000054666.11(transcript)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0030133""(transport vesicle)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061025""(membrane fusion)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:1903531""(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-56422N|panther:PTHR45701(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P51809	intact:EBI-27055396	intact:EBI-1052205|uniprotkb:Q53GY7|uniprotkb:Q7Z409|uniprotkb:Q9H4A7|ensembl:ENSP00000286448.6|ensembl:ENSP00000518622.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:vamp7_human(display_long)|uniprotkb:SYBL1(gene name synonym)|uniprotkb:Synaptobrevin-like protein 1(gene name synonym)|uniprotkb:Tetanus-insensitive VAMP(gene name synonym)|uniprotkb:VAMP7(gene name)|psi-mi:VAMP7(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000124333.16(gene)|ensembl:ENSG00000292366.1(gene)|ensembl:ENST00000286448.12(transcript)|ensembl:ENST00000711260.1(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0030027""(lamellipodium)|go:""GO:0030141""(secretory granule)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031143""(pseudopodium)|go:""GO:0031201""(SNARE complex)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043308""(eosinophil degranulation)|go:""GO:0043312""(neutrophil degranulation)|go:""GO:0043320""(natural killer cell degranulation)|go:""GO:0045202""(synapse)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903595""(positive regulation of histamine secretion by mast cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR051097|mint:P51809|rcsb pdb:2DMW|reactome:R-HSA-199992|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9020591|refseq:NP_001138621.1|refseq:NP_001172112.1|refseq:NP_005629.1|efo:""Orphanet:251510""|panther:PTHR21136(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:iGCiTvDrgrPOV7mOfivnbt02zV89606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q7KZI7	intact:EBI-27055396	intact:EBI-516560|uniprotkb:Q15449|uniprotkb:Q15524|uniprotkb:Q5XGA3|uniprotkb:Q68A18|uniprotkb:Q96HB3|uniprotkb:Q96RG0|ensembl:ENSP00000385751.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:mark2_human(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001034558.2|refseq:NP_001156768.1|refseq:NP_001156769.1|refseq:NP_004945.4|refseq:NP_059672.2|ensembl:ENSG00000072518.23(gene)|ensembl:ENST00000402010.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0001764""(neuron migration)|go:""GO:0003723""(RNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008289""(lipid binding)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0030425""(dendrite)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0050770""(regulation of axonogenesis)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051646""(mitochondrion localization)|go:""GO:0061564""(axon development)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071963""(establishment or maintenance of cell polarity regulating cell shape)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097427""(microtubule bundle)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1904526""(regulation of microtubule binding)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:Q7KZI7|rcsb pdb:3IEC|rcsb pdb:5EAK|rcsb pdb:5KZ7|rcsb pdb:5KZ8|rcsb pdb:8TXY|dip:DIP-31321N|panther:PTHR24346(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:yfUqSCu4bgkncBd6hRRg5pKkArc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9UHD8	intact:EBI-27055396	intact:EBI-851542|uniprotkb:Q96QF3|uniprotkb:Q96QF4|uniprotkb:Q96QF5|uniprotkb:Q9HA04|uniprotkb:Q9UG40|uniprotkb:Q9Y5W4|uniprotkb:A8K2V3|uniprotkb:B3KPM0|uniprotkb:B4DTL9|uniprotkb:B4E0N2|uniprotkb:B4E274|uniprotkb:B7Z654|ensembl:ENSP00000391249.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:sept9_human(display_long)|uniprotkb:SEPTIN9(gene name)|psi-mi:SEPTIN9(display_short)|uniprotkb:KIAA0991(gene name synonym)|uniprotkb:MLL septin-like fusion protein MSF-A(gene name synonym)|uniprotkb:MSF(gene name synonym)|uniprotkb:Ovarian/Breast septin(gene name synonym)|uniprotkb:SEPT9(gene name synonym)|uniprotkb:Septin D1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR18884(orthology-group)|ensembl:ENSG00000184640.20(gene)|ensembl:ENST00000427177.6(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005874""(microtubule)|go:""GO:0005930""(axoneme)|go:""GO:0005940""(septin ring)|go:""GO:0008104""(protein localization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0031105""(septin complex)|go:""GO:0032153""(cell division site)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061640""(cytoskeleton-dependent cytokinesis)|go:""GO:0097730""(non-motile cilium)|go:""GO:1902857""(positive regulation of non-motile cilium assembly)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q9UHD8|rcsb pdb:4YQF|rcsb pdb:5CYO|rcsb pdb:5CYP|refseq:NP_001106963.1|refseq:NP_001106964.1|refseq:NP_001106965.1|refseq:NP_001106966.1|refseq:NP_001106967.1|refseq:NP_001106968.1|refseq:NP_001280624.1|refseq:NP_001280625.1|refseq:NP_001280626.1|refseq:NP_001280627.1|refseq:NP_006631.2|refseq:XP_005257019.1|refseq:XP_006721706.1|refseq:XP_006721707.1|refseq:XP_011522509.1|refseq:XP_011522510.1|refseq:XP_016879520.1|refseq:XP_016879521.1|dip:DIP-36697N|efo:""Orphanet:2901"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:YzUn6hS5tAX/U+SJ8YzqzWW/dQI9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q14156	intact:EBI-27055396	intact:EBI-1049330|uniprotkb:Q2VPK2|uniprotkb:Q63HL7|uniprotkb:Q68DX1|uniprotkb:Q6IQ18|uniprotkb:A7MD19|ensembl:ENSP00000254624.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:efr3a_human(display_long)|uniprotkb:KIAA0143(gene name synonym)|uniprotkb:Protein EFR3-like(gene name synonym)|uniprotkb:EFR3A(gene name)|psi-mi:EFR3A(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000132294.15(gene)|ensembl:ENST00000254624.10(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR049152|interpro:IPR051851|mint:Q14156|refseq:NP_055952.2|refseq:NP_001310482.1|refseq:NP_001310483.1|refseq:NP_001310484.1|refseq:NP_001310485.1|refseq:NP_001310486.1|refseq:NP_001310487.1|panther:PTHR12444(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:WWG8LKAY6O+CbAZdUzEZeo4wUc09606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P50402	intact:EBI-27055396	intact:EBI-489887|ensembl:ENSP00000358857.4|ensembl:ENSP00000507533.1|uniprotkb:Q6FI02	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000102119.12(gene)|ensembl:ENST00000369842.9(transcript)|ensembl:ENST00000683627.1(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006936""(muscle contraction)|go:""GO:0007517""(muscle organ development)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071763""(nuclear membrane organization)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0160045""(TMEM240-body)|go:""GO:1990000""(amyloid fibril formation)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|refseq:NP_000108.1|efo:""Orphanet:98863""|dip:DIP-34638N|panther:PTHR15171(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O75886	intact:EBI-27055396	intact:EBI-373258|uniprotkb:Q7LDQ0|uniprotkb:Q9UF58|uniprotkb:A8K8A0|uniprotkb:D3DPA1|ensembl:ENSP00000263904.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:stam2_human(display_long)|uniprotkb:STAM2(gene name)|psi-mi:STAM2(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Hrs-binding protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_005834.4|ensembl:ENSG00000115145.10(gene)|ensembl:ENST00000263904.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0016236""(macroautophagy)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031901""(early endosome membrane)|go:""GO:0033565""(ESCRT-0 complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0090148""(membrane fission)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035675|interpro:IPR036028|interpro:IPR047493|interpro:IPR050670|mint:O75886|rcsb pdb:1X2Q|rcsb pdb:1X5B|rcsb pdb:2L0T|rcsb pdb:5CRV|rcsb pdb:5IXF|reactome:R-HSA-182971|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|panther:PTHR45929(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:e5brcAWS5So29SdnZV3cAm/dZAk9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P23528	intact:EBI-27055396	intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629.5|ensembl:ENSP00000432660.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_005498.1|ensembl:ENSG00000172757.13(gene)|ensembl:ENST00000308162.10(transcript)|ensembl:ENST00000525451.6(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0009615""(response to virus)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030043""(actin filament fragmentation)|go:""GO:0030426""(growth cone)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032587""(ruffle membrane)|go:""GO:0040019""(positive regulation of embryonic development)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0051293""(establishment of spindle localization)|go:""GO:0061001""(regulation of dendritic spine morphogenesis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|dip:DIP-33000N|panther:PTHR11913(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O96013	intact:EBI-27055396	intact:EBI-713738|uniprotkb:Q8N4E1|uniprotkb:Q8NCH5|uniprotkb:Q8NDE3|uniprotkb:Q9BU33|uniprotkb:Q9ULS8|uniprotkb:B4DGG6|ensembl:ENSP00000351049.2|ensembl:ENSP00000353625.3|ensembl:ENSP00000469413.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:pak4_human(display_long)|uniprotkb:p21-activated kinase 4(gene name synonym)|uniprotkb:PAK4(gene name)|psi-mi:PAK4(display_short)|uniprotkb:KIAA1142(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001014831.1|refseq:NP_001014832.1|refseq:NP_001014834.1|refseq:NP_001014835.1|refseq:NP_005875.1|ensembl:ENSG00000130669.17(gene)|ensembl:ENST00000358301.7(transcript)|ensembl:ENST00000360442.8(transcript)|ensembl:ENST00000593690.5(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006915""(apoptotic process)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007165""(signal transduction)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016477""(cell migration)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0060996""(dendritic spine development)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|rcsb pdb:4O0X|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|interpro:IPR051931|mint:O96013|rcsb pdb:2BVA|rcsb pdb:2CDZ|rcsb pdb:2J0I|rcsb pdb:2OV2|rcsb pdb:2Q0N|rcsb pdb:2X4Z|rcsb pdb:4APP|rcsb pdb:4FIE|rcsb pdb:4FIF|rcsb pdb:4FIG|rcsb pdb:4FIH|rcsb pdb:4FII|rcsb pdb:4FIJ|rcsb pdb:4JDH|rcsb pdb:4JDI|rcsb pdb:4JDJ|rcsb pdb:4JDK|rcsb pdb:4L67|rcsb pdb:4NJD|rcsb pdb:4O0V|rcsb pdb:4O0Y|rcsb pdb:4XBR|rcsb pdb:4XBU|rcsb pdb:5BMS|rcsb pdb:5I0B|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:5VED|rcsb pdb:5VEE|rcsb pdb:5VEF|rcsb pdb:5XVA|rcsb pdb:5XVF|rcsb pdb:5XVG|rcsb pdb:5ZJW|rcsb pdb:6WLX|rcsb pdb:6WLY|rcsb pdb:7CMB|rcsb pdb:7CP3|rcsb pdb:7CP4|rcsb pdb:7S46|rcsb pdb:7S47|rcsb pdb:7S48|rcsb pdb:8AHG|rcsb pdb:8AHH|rcsb pdb:8AHI|rcsb pdb:8YHK|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|refseq:XP_011524618.1|refseq:XP_011524619.1|refseq:XP_011524620.1|refseq:XP_011524621.1|refseq:XP_011524622.1|dip:DIP-39742N|panther:PTHR48015(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:8i8hHt/Taj+czkueFRAMhdiMkYw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P43121	intact:EBI-27055396	intact:EBI-2339969|uniprotkb:Q6ZTR2|uniprotkb:Q6PHR3|uniprotkb:O95812|uniprotkb:Q59E86|intact:EBI-25626468|ensembl:ENSP00000264036.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:muc18_human(display_long)|uniprotkb:MCAM(gene name)|psi-mi:MCAM(display_short)|uniprotkb:MUC18(gene name synonym)|uniprotkb:Melanoma-associated antigen MUC18(gene name synonym)|uniprotkb:Melanoma cell adhesion molecule(gene name synonym)|uniprotkb:Melanoma-associated antigen A32(gene name synonym)|uniprotkb:S-endo 1 endothelial-associated antigen(gene name synonym)|uniprotkb:Cell surface glycoprotein P1H12(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_006491.2|dip:DIP-52791N|ensembl:ENSG00000076706.17(gene)|ensembl:ENST00000264036.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0003094""(glomerular filtration)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0061042""(vascular wound healing)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR051116|mint:P43121|rcsb pdb:6LYN|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR11973(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:f2hDslNdU/yJ8Ni66Wnsr1YE7Uw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q5JTV8	intact:EBI-27055396	intact:EBI-2559665|ensembl:ENSP00000476687.1|uniprotkb:Q9H8Y6|uniprotkb:Q8IZ65|uniprotkb:Q5JTV6|uniprotkb:B0QZ57|uniprotkb:Q9Y3X5|uniprotkb:Q9HAJ1|uniprotkb:Q9NV52|uniprotkb:A8K630|intact:EBI-40264785|uniprotkb:A0A0A0MSK5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:toip1_human(display_long)|uniprotkb:TOR1AIP1(gene name)|psi-mi:TOR1AIP1(display_short)|uniprotkb:Lamin-associated protein 1B(gene name synonym)|uniprotkb:LAP1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000143337.19(gene)|ensembl:ENST00000606911.7(transcript)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0051117""(ATPase binding)|go:""GO:0071763""(nuclear membrane organization)|go:""GO:0090435""(protein localization to nuclear envelope)|interpro:IPR008662(Lamina-associated polypeptide 1C)|interpro:IPR038599|interpro:IPR046753|interpro:IPR046754|mint:Q5JTV8|rcsb pdb:4TVS|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_001254507.1|refseq:NP_056417.2|dip:DIP-56692N|efo:""Orphanet:424261""|panther:PTHR18843(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:qFH5HTm3fcIwmGL486H8IqZHG489606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q07666	intact:EBI-27055396	intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829.7	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|panther:PTHR11208(orthology-group)|ensembl:ENSG00000121774.18(gene)|ensembl:ENST00000327300.12(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0016020""(membrane)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046831""(regulation of RNA export from nucleus)|go:""GO:0046833""(positive regulation of RNA export from nucleus)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070618""(Grb2-Sos complex)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|interpro:IPR045071|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|rcsb pdb:7Z89|rcsb pdb:7Z8A|rcsb pdb:7Z9A|rcsb pdb:7Z9B|rcsb pdb:7ZAB|rcsb pdb:7ZAC|rcsb pdb:7ZAF|rcsb pdb:7ZAM|reactome:R-HSA-8849468"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9UIQ6	intact:EBI-27055396	intact:EBI-2805360|uniprotkb:O00769|uniprotkb:Q9TNQ2|uniprotkb:Q9TNQ3|uniprotkb:Q9UIQ7|uniprotkb:Q59H76|uniprotkb:Q15145|ensembl:ENSP00000231368.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lcap_human(display_long)|uniprotkb:OTASE(gene name synonym)|uniprotkb:Oxytocinase(gene name synonym)|uniprotkb:Insulin-regulated membrane aminopeptidase(gene name synonym)|uniprotkb:Insulin-responsive aminopeptidase(gene name synonym)|uniprotkb:Placental leucine aminopeptidase(gene name synonym)|uniprotkb:LNPEP(gene name)|psi-mi:LNPEP(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_005566.2|refseq:NP_787116.2|ensembl:ENSG00000113441.16(gene)|ensembl:ENST00000231368.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0002480""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007565""(female pregnancy)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0042277""(peptide binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|interpro:IPR045357|interpro:IPR050344|mint:Q9UIQ6|rcsb pdb:4P8Q|rcsb pdb:4PJ6|rcsb pdb:4Z7I|rcsb pdb:5C97|rcsb pdb:5JHQ|rcsb pdb:5MJ6|rcsb pdb:7ZYF|rcsb pdb:8CGP|rcsb pdb:8CGW|rcsb pdb:8P0I|reactome:R-HSA-1236977|reactome:R-HSA-1445148|reactome:R-HSA-983168|panther:PTHR11533(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:IOU7GW8f6aBYAjIUQXFKbU5Hqkw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O15173	intact:EBI-27055396	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425.4|ensembl:ENSP00000429301.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_006311.2|ensembl:ENSG00000164040.18(gene)|ensembl:ENST00000296425.10(transcript)|ensembl:ENST00000520121.6(transcript)|go:""GO:0003707""(nuclear steroid receptor activity)|go:""GO:0005496""(steroid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0012505""(endomembrane system)|go:""GO:0015232""(heme transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0060612""(adipose tissue development)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|interpro:IPR050577|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9707616|panther:PTHR10281(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O95372	intact:EBI-27055396	intact:EBI-715999|uniprotkb:Q7Z4Z2|ensembl:ENSP00000363638.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lypa2_human(display_long)|uniprotkb:Lysophospholipase II(gene name synonym)|uniprotkb:LYPLA2(gene name)|psi-mi:LYPLA2(display_short)|uniprotkb:APT2(gene name synonym)|uniprotkb:Palmitoyl-protein hydrolase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_009191.1|ensembl:ENSG00000011009.12(gene)|ensembl:ENST00000374514.8(transcript)|go:""GO:0002084""(protein depalmitoylation)|go:""GO:0004622""(lysophospholipase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005795""(Golgi stack)|go:""GO:0005829""(cytosol)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0007411""(axon guidance)|go:""GO:0008474""(""palmitoyl-(protein) hydrolase activity"")|go:""GO:0045296""(cadherin binding)|go:""GO:0046464""(acylglycerol catabolic process)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905344""(prostaglandin catabolic process)|interpro:IPR003140(Phospholipase/carboxylesterase)|interpro:IPR029058|interpro:IPR050565|mint:O95372|rcsb pdb:5SYN|rcsb pdb:6BJE|reactome:R-HSA-373760|panther:PTHR10655(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:yJ0IGnOIc6UvuzuLdZb8WzlN9aY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O95490	intact:EBI-27055396	intact:EBI-2865302|uniprotkb:Q9UKY5|uniprotkb:B1ALT9|uniprotkb:B1ALU0|uniprotkb:Q9UKY6|uniprotkb:B1ALT8|uniprotkb:O94882|uniprotkb:Q5VX76|uniprotkb:A5XEI2|uniprotkb:B1ALU2|uniprotkb:B1ALU4|uniprotkb:B1ALU5|uniprotkb:B1ALU6|ensembl:ENSP00000359752.3|ensembl:ENSP00000359763.1|intact:EBI-28986872	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:agrl2_human(display_long)|uniprotkb:ADGRL2(gene name)|psi-mi:ADGRL2(display_short)|uniprotkb:Calcium-independent alpha-latrotoxin receptor 2(gene name synonym)|uniprotkb:KIAA0786(gene name synonym)|uniprotkb:LEC1(gene name synonym)|uniprotkb:LPHH1(gene name synonym)|uniprotkb:LPHN2(gene name synonym)|uniprotkb:Latrophilin homolog 1(gene name synonym)|uniprotkb:Latrophilin-2(gene name synonym)|uniprotkb:Lectomedin-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_036434.1|refseq:XP_005270723.1|refseq:NP_001284633.1|refseq:NP_001284634.1|refseq:NP_001284635.1|refseq:NP_001317574.1|refseq:XP_016856276.1|ensembl:ENSG00000117114.21(gene)|ensembl:ENST00000370717.6(transcript)|ensembl:ENST00000370728.5(transcript)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016524""(latrotoxin receptor activity)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR017981|interpro:IPR017983|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159|interpro:IPR046338|mint:O95490|panther:PTHR12011(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:WkTs1zEQmAT82KxUL2+V7KG74UQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q12923	intact:EBI-27055396	intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENSG00000163629.13(gene)|ensembl:ENST00000411767.7(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|interpro:IPR000299(Band 4.1, N-terminal)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0036312""(phosphatidylinositol 3-kinase regulatory subunit binding)|go:""GO:0044297""(cell body)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097237""(cellular response to toxic substance)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1904890""(negative regulation of excitatory synapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|interpro:IPR052074|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|rcsb pdb:7QCX|rcsb pdb:7QCY|rcsb pdb:7XTY|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-40449N|panther:PTHR46900(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q07157	intact:EBI-27055396	intact:EBI-79553|uniprotkb:B4E3K1|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6|ensembl:ENSP00000281537.7|ensembl:ENSP00000484535.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein ZO-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_003248.3|refseq:NP_783297.2|panther:PTHR13865(orthology-group)|ensembl:ENSG00000104067.17(gene)|ensembl:ENSG00000277401.4(gene)|ensembl:ENST00000346128.10(transcript)|ensembl:ENST00000621049.4(transcript)|go:""GO:0002102""(podosome)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005921""(gap junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034334""(adherens junction maintenance)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0036305""(ameloblast differentiation)|go:""GO:0042995""(cell projection)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043296""(apical junction complex)|go:""GO:0045177""(apical part of cell)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0070160""(tight junction)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0090557""(establishment of endothelial intestinal barrier)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1901888""(regulation of cell junction assembly)|go:""GO:1902396""(protein localization to bicellular tight junction)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1905605""(positive regulation of blood-brain barrier permeability)|go:""GO:2000049""(positive regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035597|interpro:IPR036028|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|reactome:R-HSA-9705677"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O75976	intact:EBI-27055396	intact:EBI-3916308|uniprotkb:B7Z7T9|uniprotkb:B7ZAU4|uniprotkb:F5GZH6|uniprotkb:Q86SH9|uniprotkb:O15377|uniprotkb:Q86XE6|ensembl:ENSP00000225719.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:cbpd_human(display_long)|uniprotkb:CPD(gene name)|psi-mi:CPD(display_short)|uniprotkb:Metallocarboxypeptidase D(gene name synonym)|uniprotkb:gp180(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001295.2|refseq:NP_001186704.1|ensembl:ENSG00000108582.12(gene)|ensembl:ENST00000225719.9(transcript)|go:""GO:0004181""(metallocarboxypeptidase activity)|go:""GO:0004185""(serine-type carboxypeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006518""(peptide metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0016485""(protein processing)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR033848|interpro:IPR034224|interpro:IPR050753|mint:O75976|rcsb pdb:5AQ0|reactome:R-HSA-432722|reactome:R-HSA-9696264|reactome:R-HSA-9696273|panther:PTHR11532(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:PC6PFm4D7KoT4utNwyIe57VUwbY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9HB21	intact:EBI-27055396	intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986.3|ensembl:ENSP00000376547.3|ensembl:ENSP00000394416.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:XP_005270073.1|refseq:XP_005270078.1|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679.15(gene)|ensembl:ENST00000368990.8(transcript)|ensembl:ENST00000392799.7(transcript)|ensembl:ENST00000433307.2(transcript)|go:""GO:0001553""(luteinization)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008209""(androgen metabolic process)|go:""GO:0008210""(estrogen metabolic process)|go:""GO:0009791""(post-embryonic development)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0031529""(ruffle organization)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033327""(Leydig cell differentiation)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0043325""(phosphatidylinositol-3,4-bisphosphate binding)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060021""(roof of mouth development)|go:""GO:0060325""(face morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070301""(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR051707|mint:Q9HB21|rcsb pdb:1EAZ|reactome:R-HSA-1660499|panther:PTHR14336(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q13151	intact:EBI-27055396	intact:EBI-724092|intact:EBI-1043661|uniprotkb:Q6IB18|ensembl:ENSP00000316042.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_006796.1|ensembl:ENSG00000177733.8(gene)|ensembl:ENST00000314940.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0006954""(inflammatory response)|go:""GO:0019901""(protein kinase binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0045202""(synapse)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|panther:PTHR48024(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P36542	intact:EBI-27055396	intact:EBI-711768|ensembl:ENSP00000349142.7|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000165629.20(gene)|ensembl:ENST00000356708.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016020""(membrane)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|rcsb pdb:8H9E|rcsb pdb:8H9F|rcsb pdb:8H9I|rcsb pdb:8H9J|rcsb pdb:8H9L|rcsb pdb:8H9M|rcsb pdb:8H9P|rcsb pdb:8H9Q|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|reactome:R-HSA-9837999|refseq:NP_001001973.1|refseq:NP_005165.1|panther:PTHR11693(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q00325	intact:EBI-27055396	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|uniprotkb:Q7Z7N7|uniprotkb:B3KS34|ensembl:ENSP00000228318.3|ensembl:ENSP00000447310.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:s25a3_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Phosphate carrier protein, mitochondrial(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR45671(orthology-group)|ensembl:ENSG00000075415.15(gene)|ensembl:ENST00000228318.8(transcript)|ensembl:ENST00000551917.5(transcript)|go:""GO:0005315""(phosphate transmembrane transporter activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0015317""(""phosphate:proton symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0035435""(phosphate ion transmembrane transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990547""(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|efo:""Orphanet:91130"""	-	-	crc64:78714C85931B22D5	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:A0FGR8	intact:EBI-27055396	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0006897""(endocytosis)|go:""GO:0008429""(phosphatidylethanolamine binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0044232""(organelle membrane contact site)|go:""GO:0045296""(cadherin binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0140268""(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|interpro:IPR051634|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-9845576|panther:PTHR45761(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q15334	intact:EBI-27055396	intact:EBI-299979|uniprotkb:O00188|uniprotkb:Q58F11|uniprotkb:Q86UK6|uniprotkb:A7MBM7|ensembl:ENSP00000321537.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:l2gl1_human(display_long)|uniprotkb:DLG4(gene name synonym)|uniprotkb:LLGL1(gene name)|psi-mi:LLGL1(display_short)|uniprotkb:Human homolog to the D-lgl gene protein(gene name synonym)|uniprotkb:Hugl-1(gene name synonym)|uniprotkb:HUGL(gene name synonym)|uniprotkb:HUGL1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000131899.13(gene)|ensembl:ENST00000316843.9(transcript)|go:""GO:0000137""(Golgi cis cisterna)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0007409""(axonogenesis)|go:""GO:0008593""(regulation of Notch signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030424""(axon)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032878""(regulation of establishment or maintenance of cell polarity)|go:""GO:0045159""(myosin II binding)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0051294""(establishment of spindle orientation)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR000664(""Lethal(2) giant larvae protein"")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q15334|refseq:NP_004131.3|panther:PTHR10241(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:VqlrgKVnWmXyx1lvnpRe9hRQD0Q9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P51648	intact:EBI-27055396	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643.6|ensembl:ENSP00000461916.2|ensembl:ENSP00000463637.1|ensembl:ENSP00000500092.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR43570(orthology-group)|efo:""Orphanet:816""|ensembl:ENSG00000072210.19(gene)|ensembl:ENST00000176643.11(transcript)|ensembl:ENST00000579855.5(transcript)|ensembl:ENST00000581518.6(transcript)|ensembl:ENST00000672357.1(transcript)|go:""GO:0004028""(3-chloroallyl aldehyde dehydrogenase activity)|go:""GO:0004029""(""aldehyde dehydrogenase (NAD+) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006081""(aldehyde metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006714""(sesquiterpenoid metabolic process)|go:""GO:0007417""(central nervous system development)|go:""GO:0007422""(peripheral nervous system development)|go:""GO:0008544""(epidermis development)|go:""GO:0033306""(phytol metabolic process)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046458""(hexadecanal metabolic process)|go:""GO:0046577""(long-chain-alcohol oxidase activity)|go:""GO:0050061""(""long-chain fatty aldehyde dehydrogenase (NAD+) activity"")|go:""GO:0052814""(""medium-chain fatty aldehyde dehydrogenase (NAD+) activity"")|interpro:IPR012394(""Aldehyde dehydrogenase NAD(P)-dependent"")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9845614|refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P78310	intact:EBI-27055396	intact:EBI-747931|uniprotkb:O00694|uniprotkb:Q8WWT6|uniprotkb:Q8WWT7|uniprotkb:Q8WWT8|uniprotkb:Q9UKV4|uniprotkb:B2R8V8|ensembl:ENSP00000284878.7|uniprotkb:B7WPI3|uniprotkb:D3YHP0	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:cxar_human(display_long)|uniprotkb:Coxsackievirus B-adenovirus receptor(gene name synonym)|uniprotkb:HCVADR(gene name synonym)|uniprotkb:CVB3-binding protein(gene name synonym)|uniprotkb:CXADR(gene name)|psi-mi:CXADR(display_short)|uniprotkb:CAR(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001329.1|refseq:NP_001193992.1|refseq:NP_001193993.1|refseq:NP_001193994.1|ensembl:ENSG00000154639.19(gene)|ensembl:ENST00000284878.12(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007507""(heart development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008354""(germ cell migration)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0014704""(intercalated disc)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030175""(filopodium)|go:""GO:0030426""(growth cone)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034109""(homotypic cell-cell adhesion)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0044297""(cell body)|go:""GO:0045121""(membrane raft)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0046629""(gamma-delta T cell activation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0055013""(cardiac muscle cell development)|go:""GO:0070633""(transepithelial transport)|go:""GO:0071253""(connexin binding)|go:""GO:0086067""(AV node cell to bundle of His cell communication)|go:""GO:0086072""(AV node cell-bundle of His cell adhesion involved in cell communication)|go:""GO:0086082""(cell adhesive protein binding involved in AV node cell-bundle of His cell communication)|go:""GO:0098904""(regulation of AV node cell action potential)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR052307|mint:P78310|rcsb pdb:1EAJ|rcsb pdb:1F5W|rcsb pdb:1JEW|rcsb pdb:1KAC|rcsb pdb:1P69|rcsb pdb:1P6A|rcsb pdb:1RSF|rcsb pdb:2J12|rcsb pdb:2J1K|rcsb pdb:2NPL|rcsb pdb:2W9L|rcsb pdb:2WBW|rcsb pdb:3J6L|rcsb pdb:3J6M|rcsb pdb:3J6N|rcsb pdb:3J6O|rcsb pdb:7DPZ|rcsb pdb:7DQ1|rcsb pdb:7VXZ|rcsb pdb:7VYK|rcsb pdb:7VYL|rcsb pdb:7VYM|rcsb pdb:7W14|reactome:R-HSA-198933|reactome:R-HSA-202733|refseq:NP_001193995.1|refseq:XP_011527781.1|panther:PTHR44468(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:rISYMOJkhS94FeOElTtG8w5p4hI9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q01650	intact:EBI-27055396	intact:EBI-6138761|uniprotkb:Q8IV97|uniprotkb:Q9UBN8|uniprotkb:Q9UP15|uniprotkb:Q9UQC0|ensembl:ENSP00000261622.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lat1_human(display_long)|uniprotkb:SLC7A5(gene name)|psi-mi:SLC7A5(display_short)|uniprotkb:CD98LC(gene name synonym)|uniprotkb:LAT1(gene name synonym)|uniprotkb:MPE16(gene name synonym)|uniprotkb:4F2 light chain(gene name synonym)|uniprotkb:CD98 light chain(gene name synonym)|uniprotkb:Integral membrane protein E16(gene name synonym)|uniprotkb:L-type amino acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 7 member 5(gene name synonym)|uniprotkb:y+ system cationic amino acid transporter(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_003477.4|ensembl:ENSG00000103257.10(gene)|ensembl:ENST00000261622.5(transcript)|go:""GO:0002720""(positive regulation of cytokine production involved in immune response)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015196""(L-tryptophan transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015349""(thyroid hormone transmembrane transporter activity)|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032328""(alanine transport)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042908""(xenobiotic transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0089718""(amino acid import across plasma membrane)|go:""GO:0097421""(liver regeneration)|go:""GO:0098591""(external side of apical plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903577""(cellular response to L-arginine)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904556""(L-tryptophan transmembrane transport)|go:""GO:1905460""(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:""GO:1905534""(positive regulation of L-leucine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004760(L-type amino acid transporter)|interpro:IPR050598|mint:Q01650|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|rcsb pdb:8XPU|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-71240|panther:PTHR11785(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:GrXTCUhrHMNCnvscgx1ink2opoU9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P43243	intact:EBI-27055396	intact:EBI-352602|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5|ensembl:ENSP00000378284.3|ensembl:ENSP00000482895.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000015479.20(gene)|ensembl:ENST00000394805.8(transcript)|ensembl:ENST00000618441.5(transcript)|go:""GO:0001825""(blastocyst formation)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003170""(heart valve development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005634""(nucleus)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_001181885.1|refseq:NP_001269207.1|refseq:NP_061322.2|refseq:NP_954659.1|efo:""Orphanet:600""|efo:""Orphanet:803""|panther:PTHR15592(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P68371	intact:EBI-27055396	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:65""|ensembl:ENSG00000188229.6(gene)|ensembl:ENST00000340384.5(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0005879""(axonemal microtubule)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0036126""(sperm flagellum)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0045171""(intercellular bridge)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072686""(mitotic spindle)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|rcsb pdb:7UN1|rcsb pdb:7UNG|rcsb pdb:8J07|rcsb pdb:8SH7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9833482|refseq:NP_006079.1|panther:PTHR11588(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9ULE6	intact:EBI-27055396	intact:EBI-3957166|uniprotkb:B2RMS1|uniprotkb:B9EGC6|uniprotkb:Q5JTK7|uniprotkb:Q5JTK8|ensembl:ENST00000263563|ensembl:ENSP00000263563.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:pald_human(display_long)|uniprotkb:PALD1(gene name)|psi-mi:PALD1(display_short)|uniprotkb:KIAA1274(gene name synonym)|uniprotkb:PALD(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:XP_011537939.1|refseq:XP_011537940.1|refseq:NP_055246.2|refseq:XP_016871561.1|ensembl:ENSG00000107719.10(gene)|ensembl:ENST00000263563.7(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR029021|interpro:IPR050561|mint:Q9ULE6|panther:PTHR23339(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:Qn2qNHC/kC0rsLk68yNNZUrFmc49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9BZF1	intact:EBI-27055396	intact:EBI-2684038|uniprotkb:Q52LQ3|uniprotkb:Q9P277|uniprotkb:Q8WXP8|uniprotkb:A8K1T2|uniprotkb:E9PE66|uniprotkb:E9PE68|uniprotkb:Q68D75|ensembl:ENSP00000261183.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:osbl8_human(display_long)|uniprotkb:OSBP10(gene name synonym)|uniprotkb:KIAA1451(gene name synonym)|uniprotkb:ORP8(gene name synonym)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001003712.1|refseq:NP_065892.1|refseq:XP_005268678.1|refseq:XP_006719287.1|refseq:NP_001306581.1|refseq:NP_001306584.1|dip:DIP-56130N|ensembl:ENSG00000091039.17(gene)|ensembl:ENST00000261183.8(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005548""(phospholipid transporter activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0010891""(negative regulation of triglyceride storage)|go:""GO:0015485""(cholesterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0016020""(membrane)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032541""(cortical endoplasmic reticulum)|go:""GO:0036150""(phosphatidylserine acyl-chain remodeling)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0090204""(protein localization to nuclear pore)|go:""GO:0140343""(phosphatidylserine transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q9BZF1|rcsb pdb:1V88|rcsb pdb:5U77|rcsb pdb:5U78|rcsb pdb:8P7A|reactome:R-HSA-1482801|panther:PTHR10972(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:KwZ5DFeGTIM3p/yP3XBNgr/v3O09606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8NBN3	intact:EBI-27055396	intact:EBI-2687855|uniprotkb:Q9P103|uniprotkb:Q9Y3Y7|uniprotkb:Q9BS46|uniprotkb:Q6NT77|uniprotkb:Q8NCA4|ensembl:ENSP00000374484.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:tm87a_human(display_long)|uniprotkb:Elkin1(gene name synonym)|uniprotkb:PSEC0094(orf name)|uniprotkb:TMEM87A(gene name)|psi-mi:TMEM87A(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001273416.1|refseq:NP_001103973.1|refseq:NP_056312.2|ensembl:ENSG00000103978.17(gene)|ensembl:ENST00000389834.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001726""(ruffle)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0050976""(detection of mechanical stimulus involved in sensory perception of touch)|go:""GO:0071260""(cellular response to mechanical stimulus)|interpro:IPR009637(Transmembrane receptor, eukaryota)|interpro:IPR053937|interpro:IPR054101|mint:Q8NBN3|rcsb pdb:8CTJ|rcsb pdb:8HSI|rcsb pdb:8HTT|rcsb pdb:8KB4|reactome:R-HSA-8980692|panther:PTHR21229(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:GdHPH2U8wRKfLAAUi0q2lw4ZtCA9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q92692	intact:EBI-27055396	intact:EBI-718419|uniprotkb:A8K5L5|uniprotkb:O75455|uniprotkb:Q96J29|uniprotkb:Q6IBI6|ensembl:ENSP00000252483.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:nect2_human(display_long)|uniprotkb:NECTIN2(gene name)|psi-mi:NECTIN2(display_short)|uniprotkb:HVEB(gene name synonym)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:PRR2(gene name synonym)|uniprotkb:PVRL2(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001036189.1|refseq:NP_002847.1|ensembl:ENSG00000130202.10(gene)|ensembl:ENST00000252483.10(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001675""(acrosome assembly)|go:""GO:0002860""(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0002891""(positive regulation of immunoglobulin mediated immune response)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007286""(spermatid development)|go:""GO:0007289""(spermatid nucleus differentiation)|go:""GO:0009566""(fertilization)|go:""GO:0009986""(cell surface)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0019064""(fusion of virus membrane with host plasma membrane)|go:""GO:0030382""(sperm mitochondrion organization)|go:""GO:0033005""(positive regulation of mast cell activation)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042271""(susceptibility to natural killer cell mediated cytotoxicity)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043296""(apical junction complex)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0044406""(adhesion of symbiont to host)|go:""GO:0044782""(cilium organization)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046596""(regulation of viral entry into host cell)|go:""GO:0046814""(coreceptor-mediated virion attachment to host cell)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051654""(establishment of mitochondrion localization)|go:""GO:0060370""(susceptibility to T cell mediated cytotoxicity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR052659|mint:Q92692|rcsb pdb:3R0N|rcsb pdb:4DFH|rcsb pdb:4DFI|rcsb pdb:4HZA|rcsb pdb:5V52|rcsb pdb:8X6B|reactome:R-HSA-198933|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41043N|panther:PTHR47387(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:xGLJch8JXc+urj11GXKFPgBLYuc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9UJF2	intact:EBI-27055396	intact:EBI-359444|uniprotkb:O95174|uniprotkb:Q5TFU9|uniprotkb:F8W755|uniprotkb:Q2TB22|ensembl:ENSP00000420558.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ngap_human(display_long)|uniprotkb:RASAL2(gene name)|psi-mi:RASAL2(display_short)|uniprotkb:NGAP(gene name synonym)|uniprotkb:RAS protein activator-like 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_004832.1|refseq:NP_733793.2|ensembl:ENSG00000075391.18(gene)|ensembl:ENST00000462775.5(transcript)|go:""GO:0002021""(response to dietary excess)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0009749""(response to glucose)|go:""GO:0010467""(gene expression)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0060612""(adipose tissue development)|go:""GO:2000257""(regulation of protein activation cascade)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR039360|mint:Q9UJF2|reactome:R-HSA-5658442|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-27570N|panther:PTHR10194(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:nWiB+5VCXMzJXDsyu5G5QkhyQV49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q96RD7	intact:EBI-27055396	intact:EBI-7037612|uniprotkb:Q543A0|uniprotkb:O75968|uniprotkb:Q6UW26|uniprotkb:Q96L77|uniprotkb:Q96RS5|intact:MINT-3379479|uniprotkb:Q96AM9|ensembl:ENSP00000227638.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:panx1_human(display_long)|uniprotkb:PANX1(gene name)|psi-mi:PANX1(display_short)|uniprotkb:MRS1(gene name synonym)|uniprotkb:UNQ2529/PRO6028(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:488191""|dip:DIP-43936N|ensembl:ENSG00000110218.9(gene)|ensembl:ENST00000227638.8(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0002931""(response to ischemia)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005243""(gap junction channel activity)|go:""GO:0005253""(monoatomic anion channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005347""(ATP transmembrane transporter activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005921""(gap junction)|go:""GO:0006812""(monoatomic cation transport)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0015867""(ATP transport)|go:""GO:0016020""(membrane)|go:""GO:0022829""(wide pore channel activity)|go:""GO:0022840""(leak channel activity)|go:""GO:0032059""(bleb)|go:""GO:0032730""(positive regulation of interleukin-1 alpha production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033198""(response to ATP)|go:""GO:0042802""(identical protein binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0048477""(oogenesis)|go:""GO:0051015""(actin filament binding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098656""(monoatomic anion transmembrane transport)|interpro:IPR000990(Innexin)|interpro:IPR039099|mint:Q96RD7|rcsb pdb:6LTN|rcsb pdb:6LTO|rcsb pdb:6M02|rcsb pdb:6M66|rcsb pdb:6M67|rcsb pdb:6M68|rcsb pdb:6V6D|rcsb pdb:6WBF|rcsb pdb:6WBG|rcsb pdb:6WBI|rcsb pdb:6WBK|rcsb pdb:6WBL|rcsb pdb:6WBM|rcsb pdb:6WBN|rcsb pdb:7DWB|rcsb pdb:7F8J|rcsb pdb:7F8N|rcsb pdb:7F8O|rcsb pdb:7WSV|rcsb pdb:8GTS|rcsb pdb:8GTT|rcsb pdb:8GYO|reactome:R-HSA-112303|reactome:R-HSA-844456|reactome:R-HSA-9856530|refseq:NP_056183.2|panther:PTHR15759(orthology-group)"	-	-	comment:mint|function:Structural component of the gap junctions	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:4RTDyFKsL6d8oA8AsJT285+Yz1M9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P53985	intact:EBI-27055396	intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|ensembl:ENSP00000358640.4|ensembl:ENSP00000397106.2|ensembl:ENSP00000399104.2|ensembl:ENSP00000416167.2|ensembl:ENSP00000441065.1|ensembl:ENSP00000485688.1|ensembl:ENSP00000486000.1|ensembl:ENSP00000505879.1|uniprotkb:Q49A45	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000155380.13(gene)|ensembl:ENSG00000281917.4(gene)|ensembl:ENST00000369626.8(transcript)|ensembl:ENST00000429288.2(transcript)|ensembl:ENST00000443580.6(transcript)|ensembl:ENST00000458229.6(transcript)|ensembl:ENST00000538576.5(transcript)|ensembl:ENST00000628110.2(transcript)|ensembl:ENST00000630362.4(transcript)|ensembl:ENST00000679803.1(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007098""(centrosome cycle)|go:""GO:0008028""(monocarboxylic acid transmembrane transporter activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0015129""(lactate transmembrane transporter activity)|go:""GO:0015130""(mevalonate transmembrane transporter activity)|go:""GO:0015141""(succinate transmembrane transporter activity)|go:""GO:0015650""(""lactate:proton symporter activity"")|go:""GO:0015718""(monocarboxylic acid transport)|go:""GO:0015728""(mevalonate transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0030054""(cell junction)|go:""GO:0032094""(response to food)|go:""GO:0035879""(plasma membrane lactate transport)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042867""(pyruvate catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0046943""(carboxylic acid transmembrane transporter activity)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0051780""(behavioral response to nutrient)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0071422""(succinate transmembrane transport)|go:""GO:0097159""(obsolete organic cyclic compound binding)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901475""(pyruvate transmembrane transport)|go:""GO:1905039""(carboxylic acid transmembrane transport)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|interpro:IPR050327|mint:P53985|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|rcsb pdb:7YR5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-9749641|refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|efo:""Orphanet:165991""|efo:""Orphanet:171690""|efo:""Orphanet:438075""|panther:PTHR11360(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9UHA4	intact:EBI-27055396	intact:EBI-1038192|uniprotkb:Q9H364|uniprotkb:J3KMX4|uniprotkb:B2R4A1|ensembl:ENSP00000424183.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ltor3_human(display_long)|uniprotkb:MAP2K1IP1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase 1-interacting protein 1(gene name synonym)|uniprotkb:LAMTOR3(gene name)|psi-mi:LAMTOR3(display_short)|uniprotkb:PRO2783(orf name)|uniprotkb:MEK-binding partner 1(gene name synonym)|uniprotkb:MAPKSP1(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase scaffold protein 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_068805.1|refseq:NP_001230665.1|ensembl:ENSG00000109270.13(gene)|ensembl:ENST00000499666.7(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008104""(protein localization)|go:""GO:0010008""(endosome membrane)|go:""GO:0019209""(kinase activator activity)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0035579""(specific granule membrane)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071986""(Ragulator complex)|go:""GO:1902414""(protein localization to cell junction)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990877""(FNIP-folliculin RagC/D GAP)|interpro:IPR015019(Mitogen-activated protein kinase kinase 1 interacting)|mint:Q9UHA4|rcsb pdb:1SKO|rcsb pdb:2ZL1|rcsb pdb:3CPT|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6B9X|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|rcsb pdb:6WJ2|rcsb pdb:6WJ3|rcsb pdb:7T3A|rcsb pdb:7T3B|rcsb pdb:7T3C|rcsb pdb:7UX2|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8DHB|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-8943724|reactome:R-HSA-9639288|panther:PTHR13378(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:0QvFsMOMU2EZyUVVVUqBij+gsKw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P52799	intact:EBI-27055396	intact:EBI-7532268|intact:MINT-3019741|uniprotkb:Q5JV56|ensembl:ENSP00000493716.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:efnb2_human(display_long)|uniprotkb:EFNB2(gene name)|psi-mi:EFNB2(display_short)|uniprotkb:EPLG5(gene name synonym)|uniprotkb:HTKL(gene name synonym)|uniprotkb:LERK5(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 5(gene name synonym)|uniprotkb:HTK ligand(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_004084.1|ensembl:ENSG00000125266.8(gene)|ensembl:ENST00000646441.1(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001945""(lymph vessel development)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007411""(axon guidance)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010839""(negative regulation of keratinocyte proliferation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0030425""(dendrite)|go:""GO:0031295""(T cell costimulation)|go:""GO:0034332""(adherens junction organization)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043616""(keratinocyte proliferation)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048514""(blood vessel morphogenesis)|go:""GO:0048845""(venous blood vessel morphogenesis)|go:""GO:0050920""(regulation of chemotaxis)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0072178""(nephric duct morphogenesis)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099054""(presynapse assembly)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1903849""(positive regulation of aorta morphogenesis)|go:""GO:2000727""(positive regulation of cardiac muscle cell differentiation)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P52799|rcsb pdb:2HLE|rcsb pdb:2I85|rcsb pdb:2VSK|rcsb pdb:2VSM|rcsb pdb:2WO2|rcsb pdb:3GXU|rcsb pdb:4UF7|rcsb pdb:6P7Y|rcsb pdb:6PDL|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|dip:DIP-46378N|panther:PTHR11304(orthology-group)"	-	-	comment:mint|function:Binds to the receptor tyrosine kinases EPHB4 and EPHA3. May play a role in constraining the orientation of longitudinally projecting axons	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:Ie9xTJNgMD4VdbCiT9rJf1XCgqE9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O15260	intact:EBI-27055396	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|uniprotkb:B7Z6A4|ensembl:ENSP00000361057.3|ensembl:ENSP00000486049.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_149351.1|refseq:NP_001267718.1|refseq:NP_001267721.1|ensembl:ENSG00000148248.14(gene)|ensembl:ENSG00000280951.3(gene)|ensembl:ENST00000371989.8(transcript)|ensembl:ENST00000629578.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0010638""(positive regulation of organelle organization)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032368""(regulation of lipid transport)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:0097020""(COPII receptor activity)|go:""GO:0140353""(lipid export from cell)|interpro:IPR002995(Surfeit locus 4)|interpro:IPR045214|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|panther:PTHR23427(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P35613	intact:EBI-27055396	intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|ensembl:ENSG00000172270.22(gene)|ensembl:ENST00000333511.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0003407""(neural retina development)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007566""(embryo implantation)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045494""(photoreceptor cell maintenance)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0046689""(response to mercury ion)|go:""GO:0046697""(decidualization)|go:""GO:0051591""(response to cAMP)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:1904466""(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:3QR2|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|rcsb pdb:7DAA|rcsb pdb:7DCE|rcsb pdb:7XY8|rcsb pdb:8XEJ|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-9749641|refseq:XP_016882662.1|dip:DIP-50310N|panther:PTHR10075(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8IZ21	intact:EBI-27055396	intact:EBI-3938822|uniprotkb:Q68DD4|uniprotkb:B9ZVW0|uniprotkb:Q9H395|uniprotkb:Q9H6X0|uniprotkb:Q8N384|uniprotkb:Q6NUN6|uniprotkb:Q9H8W6|uniprotkb:D3DPM3|uniprotkb:A2APK6|ensembl:ENSP00000362945.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:phar4_human(display_long)|uniprotkb:PHACTR4(gene name)|psi-mi:PHACTR4(display_short)|uniprotkb:PRO2963(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001041648.1|refseq:NP_076412.3|refseq:XP_016857657.1|refseq:XP_016857662.1|dip:DIP-47323N|ensembl:ENSG00000204138.13(gene)|ensembl:ENST00000373839.8(transcript)|go:""GO:0001755""(neural crest cell migration)|go:""GO:0001843""(neural tube closure)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0043085""(positive regulation of catalytic activity)|go:""GO:0048484""(enteric nervous system development)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0061386""(closure of optic fissure)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:2001045""(negative regulation of integrin-mediated signaling pathway)|interpro:IPR004018(RPEL repeat)|mint:Q8IZ21|panther:PTHR12751(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:RaPU7amt8Ztkr4p8+PMGSs5Pw4I9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q5T0W9	intact:EBI-27055396	intact:EBI-2556565|uniprotkb:Q96DQ2|uniprotkb:Q2M1P3|ensembl:ENSP00000304078.7	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:fa83b_human(display_long)|uniprotkb:C6orf143(gene name synonym)|uniprotkb:FAM83B(gene name)|psi-mi:FAM83B(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001010872.1|refseq:XP_011512696.1|refseq:XP_011512697.1|refseq:XP_006715085.1|refseq:XP_016865967.1|ensembl:ENSG00000168143.9(gene)|ensembl:ENST00000306858.8(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0036312""(phosphatidylinositol 3-kinase regulatory subunit binding)|go:""GO:0036313""(phosphatidylinositol 3-kinase catalytic subunit binding)|go:""GO:0045742""(positive regulation of epidermal growth factor receptor signaling pathway)|interpro:IPR012461(Protein of unknown function DUF1669)|interpro:IPR050944|mint:Q5T0W9|rcsb pdb:5LZK|rcsb pdb:5QHI|rcsb pdb:5QHJ|rcsb pdb:5QHK|rcsb pdb:5QHL|rcsb pdb:5QHM|rcsb pdb:5QHN|rcsb pdb:5QHO|rcsb pdb:5QHP|rcsb pdb:5QHQ|rcsb pdb:5QHR|rcsb pdb:5QHS|reactome:R-HSA-177929|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|panther:PTHR16181(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:WzQTBg74ImTqkPDdKRM0YVcGXPY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q5TH69	intact:EBI-27055396	intact:EBI-5235513|uniprotkb:Q76MU8|uniprotkb:Q8N4Y4|uniprotkb:Q96CH9|uniprotkb:Q96P46|uniprotkb:Q9ULH6|ensembl:ENSP00000251691.4|uniprotkb:C5NM88	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:big3_human(display_long)|uniprotkb:ARFGEF3(gene name)|psi-mi:ARFGEF3(display_short)|uniprotkb:BIG3(gene name synonym)|uniprotkb:C6orf92(gene name synonym)|uniprotkb:KIAA1244(gene name synonym)|uniprotkb:ARFGEF family member 3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_065073.3|ensembl:ENSG00000112379.9(gene)|ensembl:ENST00000251691.5(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032012""(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032629|interpro:IPR046455|mint:Q5TH69|panther:PTHR10663(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:aIEMWbaJHhD/6xtohTJxz6xbNVY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9Y6M5	intact:EBI-27055396	intact:EBI-10982148|uniprotkb:Q0VAK9|uniprotkb:Q9BZF6|ensembl:ENSP00000355968.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:znt1_human(display_long)|uniprotkb:Zinc transporter 1(gene name synonym)|uniprotkb:SLC30A1(gene name)|psi-mi:SLC30A1(display_short)|uniprotkb:Solute carrier family 30 member 1(gene name synonym)|uniprotkb:ZNT1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_067017.2|ensembl:ENSG00000170385.10(gene)|ensembl:ENST00000367001.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005385""(zinc ion transmembrane transporter activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006829""(zinc ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0010312""(detoxification of zinc ion)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0030315""(T-tubule)|go:""GO:0030425""(dendrite)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0046872""(metal ion binding)|go:""GO:0046929""(negative regulation of neurotransmitter secretion)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0062111""(zinc ion import into organelle)|go:""GO:0070509""(calcium ion import)|go:""GO:0070574""(cadmium ion transmembrane transport)|go:""GO:0071577""(zinc ion transmembrane transport)|go:""GO:0071584""(negative regulation of zinc ion transmembrane import)|go:""GO:0071585""(detoxification of cadmium ion)|go:""GO:0090281""(negative regulation of calcium ion import)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0099573""(glutamatergic postsynaptic density)|go:""GO:0140826""(""zinc:proton antiporter activity"")|go:""GO:0140882""(zinc export across plasma membrane)|go:""GO:1902897""(regulation of postsynaptic density protein 95 clustering)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|mint:Q9Y6M5|rcsb pdb:8J2G|rcsb pdb:8ZSB|rcsb pdb:8ZSZ|reactome:R-HSA-435368|panther:PTHR45820(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:XL8LmzhYwIWnN1yPFHnDkoJg2TE9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q02978	intact:EBI-27055396	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|uniprotkb:F5GY65|ensembl:ENSP00000225665.7	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:29072""|ensembl:ENSG00000108528.14(gene)|ensembl:ENST00000225665.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006869""(lipid transport)|go:""GO:0015116""(sulfate transmembrane transporter activity)|go:""GO:0015117""(thiosulfate transmembrane transporter activity)|go:""GO:0015131""(oxaloacetate transmembrane transporter activity)|go:""GO:0015140""(malate transmembrane transporter activity)|go:""GO:0015141""(succinate transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015367""(""oxoglutarate:malate antiporter activity"")|go:""GO:0015709""(thiosulfate transport)|go:""GO:0015729""(oxaloacetate transport)|go:""GO:0035435""(phosphate ion transmembrane transport)|go:""GO:0043490""(malate-aspartate shuttle)|go:""GO:0071422""(succinate transmembrane transport)|go:""GO:0071423""(malate transmembrane transport)|go:""GO:1902358""(sulfate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR050391|mint:Q02978|reactome:R-HSA-428643|reactome:R-HSA-9856872|refseq:NP_003553.2|panther:PTHR45618(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8IUW5	intact:EBI-27055396	intact:EBI-11343385|uniprotkb:Q8NBK1|ensembl:ENSP00000313385.4|ensembl:ENSP00000398778.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:rell1_human(display_long)|uniprotkb:RELL1(gene name)|psi-mi:RELL1(display_short)|uniprotkb:PSEC0162(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001078868.1|refseq:NP_001078869.1|ensembl:ENSG00000181826.10(gene)|ensembl:ENST00000314117.8(transcript)|ensembl:ENST00000454158.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:1900745""(positive regulation of p38MAPK cascade)|interpro:IPR022248|interpro:IPR042315|mint:Q8IUW5|panther:PTHR31037(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:in0yR+RiPdt1RmVWn5x9ad0kcws9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q96QD8	intact:EBI-27055396	intact:EBI-723083|uniprotkb:Q6ZMG2|uniprotkb:Q9HAV3|uniprotkb:Q9NVA8|uniprotkb:Q9P2G5|uniprotkb:Q6IA88|ensembl:ENSP00000256689.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:s38a2_human(display_long)|uniprotkb:ATA2(gene name synonym)|uniprotkb:KIAA1382(gene name synonym)|uniprotkb:SAT2(gene name synonym)|uniprotkb:SNAT2(gene name synonym)|uniprotkb:Amino acid transporter A2(gene name synonym)|uniprotkb:System A amino acid transporter 2(gene name synonym)|uniprotkb:System N amino acid transporter 2(gene name synonym)|uniprotkb:System A transporter 1(gene name synonym)|uniprotkb:Solute carrier family 38 member 2(gene name synonym)|uniprotkb:Protein 40-9-1(gene name synonym)|uniprotkb:SLC38A2(gene name)|psi-mi:SLC38A2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_061849.2|refseq:NP_001294865.1|ensembl:ENSG00000134294.14(gene)|ensembl:ENST00000256689.10(transcript)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005283""(""amino acid:sodium symporter activity"")|go:""GO:0005295""(""neutral L-amino acid:sodium symporter activity"")|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0006868""(glutamine transport)|go:""GO:0007565""(female pregnancy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015172""(acidic amino acid transmembrane transporter activity)|go:""GO:0015186""(L-glutamine transmembrane transporter activity)|go:""GO:0015194""(L-serine transmembrane transporter activity)|go:""GO:0015655""(""alanine:sodium symporter activity"")|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0015824""(proline transport)|go:""GO:0015825""(L-serine transport)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031460""(glycine betaine transport)|go:""GO:0032328""(alanine transport)|go:""GO:0033120""(positive regulation of RNA splicing)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043090""(amino acid import)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0080135""(regulation of cellular response to stress)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1903294""(regulation of glutamate secretion, neurotransmission)|go:""GO:1903803""(L-glutamine import across plasma membrane)|go:""GO:1903812""(L-serine import across plasma membrane)|go:""GO:1903841""(""cellular response to arsenite(3-)"")|go:""GO:1904271""(L-proline import across plasma membrane)|interpro:IPR013057(Amino acid transporter, transmembrane)|mint:Q96QD8|reactome:R-HSA-210500|reactome:R-HSA-352230|panther:PTHR22950(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:2L7TtYR3hQkSrpC/Ig4ODtgCad09606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9HCM4	intact:EBI-27055396	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|ensembl:ENSG00000115109.14(gene)|ensembl:ENST00000263713.10(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001839""(neural plate morphogenesis)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0003383""(apical constriction)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006931""(substrate-dependent cell migration, cell attachment to substrate)|go:""GO:0007398""(ectoderm development)|go:""GO:0007492""(endoderm development)|go:""GO:0007509""(mesoderm migration involved in gastrulation)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009826""(unidimensional cell growth)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032525""(somite rostral/caudal axis specification)|go:""GO:0032587""(ruffle membrane)|go:""GO:0048319""(axial mesoderm morphogenesis)|go:""GO:0048339""(paraxial mesoderm development)|go:""GO:0048617""(embryonic foregut morphogenesis)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0070201""(regulation of establishment of protein localization)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|mint:Q9HCM4|reactome:R-HSA-6794361|refseq:NP_001317239.1|panther:PTHR23280(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P02786	intact:EBI-27055396	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224.4|ensembl:ENSP00000376197.3|ensembl:ENSP00000513646.1|ensembl:ENSP00000513654.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:476113""|ensembl:ENSG00000072274.14(gene)|ensembl:ENST00000360110.9(transcript)|ensembl:ENST00000392396.7(transcript)|ensembl:ENST00000698280.1(transcript)|ensembl:ENST00000698291.1(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004998""(transferrin receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010039""(response to iron ion)|go:""GO:0010042""(response to manganese ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010637""(negative regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033572""(transferrin transport)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0046688""(response to copper ion)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0072562""(blood microparticle)|go:""GO:0098944""(postsynaptic recycling endosome membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|interpro:IPR046450|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|rcsb pdb:7ZQS|rcsb pdb:8P0Z|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9725554|refseq:NP_001121620.1|refseq:NP_001300894.1|refseq:NP_001300895.1|refseq:NP_003225.2|dip:DIP-2736N|panther:PTHR10404(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q14978	intact:EBI-27055396	intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197.17(gene)|ensembl:ENST00000605788.6(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001650""(fibrillar center)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006364""(rRNA processing)|go:""GO:0006417""(regulation of translation)|go:""GO:0007000""(nucleolus organization)|go:""GO:0014029""(neural crest formation)|go:""GO:0014032""(neural crest cell development)|go:""GO:0015030""(Cajal body)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0140678""(molecular function inhibitor activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|interpro:IPR039191|mint:Q14978|panther:PTHR23216(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q6WKZ4	intact:EBI-27055396	intact:EBI-1043591|uniprotkb:Q6AZK4|uniprotkb:Q6WKZ2|uniprotkb:Q6WKZ6|uniprotkb:Q86YV4|uniprotkb:Q8TDL1|uniprotkb:Q9H642|ensembl:ENSP00000331342.4|uniprotkb:J3KNP0|uniprotkb:Q307T1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:rfip1_human(display_long)|uniprotkb:Rab-coupling protein(gene name synonym)|uniprotkb:RAB11FIP1(gene name)|psi-mi:RAB11FIP1(display_short)|uniprotkb:RCP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001002814.2|refseq:NP_079427.4|ensembl:ENSG00000156675.16(gene)|ensembl:ENST00000330843.9(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0015031""(protein transport)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0055037""(recycling endosome)|go:""GO:0070164""(negative regulation of adiponectin secretion)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR019018|interpro:IPR035892|interpro:IPR037245|interpro:IPR037789|mint:Q6WKZ4|rcsb pdb:4D0G|panther:PTHR15746(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:5q5W3XNBpdXFd6Ikjaj86SZ/5Zw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9C0B5	intact:EBI-27055396	intact:EBI-2799626|uniprotkb:Q8TAK8|uniprotkb:Q9H923|uniprotkb:Q9UFI7|uniprotkb:Q6ZMF0|uniprotkb:Q2TGF0|ensembl:ENSP00000287169.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:zdhc5_human(display_long)|uniprotkb:KIAA1748(gene name synonym)|uniprotkb:ZNF375(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 5(gene name synonym)|uniprotkb:Zinc finger protein 375(gene name synonym)|uniprotkb:ZDHHC5(gene name)|psi-mi:ZDHHC5(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:XP_011543201.1|refseq:XP_011543202.1|refseq:XP_011543203.1|refseq:NP_056272.2|ensembl:ENSG00000156599.11(gene)|ensembl:ENST00000287169.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0016020""(membrane)|go:""GO:0016409""(palmitoyltransferase activity)|go:""GO:0018345""(protein palmitoylation)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0030425""(dendrite)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0062208""(positive regulation of pattern recognition receptor signaling pathway)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099091""(postsynaptic specialization, intracellular component)|go:""GO:0140639""(positive regulation of pyroptotic inflammatory response)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905171""(positive regulation of protein localization to phagocytic vesicle)|interpro:IPR001594(Zinc finger, DHHC-type)|mint:Q9C0B5|reactome:R-HSA-9694548|panther:PTHR12349(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:4EKCQeKXifPU/7fv6uPuHE7b1rU9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O15400	intact:EBI-27055396	intact:EBI-3221827|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579|ensembl:ENSP00000356918.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N|go:""GO:0005765""(lysosomal membrane)|ensembl:ENSG00000079950.14(gene)|ensembl:ENST00000367941.7(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0012505""(endomembrane system)|go:""GO:0019869""(chloride channel inhibitor activity)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0042582""(azurophil granule)|go:""GO:0048278""(vesicle docking)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051640""(organelle localization)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070820""(tertiary granule)|go:""GO:0070925""(organelle assembly)|go:""GO:1902685""(positive regulation of receptor localization to synapse)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR045242|mint:O15400|panther:PTHR19957(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:lFaq26g0qeP7ObMMKexuZamQgps9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P48729	intact:EBI-27055396	intact:EBI-1383726|uniprotkb:Q96HD2|uniprotkb:Q5U046|uniprotkb:Q5U047|uniprotkb:Q6FGA2|uniprotkb:Q4JJA0|uniprotkb:Q9UDK3|uniprotkb:D3DQG0|uniprotkb:D3DQG1|uniprotkb:Q71TU5|intact:EBI-11048253|ensembl:ENSP00000367074.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:kc1a_human(display_long)|uniprotkb:CSNK1A1(gene name)|psi-mi:CSNK1A1(display_short)|uniprotkb:CK1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001020276.1|refseq:NP_001883.4|refseq:NP_001258670.1|refseq:NP_001258671.1|ensembl:ENSG00000113712.19(gene)|ensembl:ENST00000377843.8(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007030""(Golgi organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016607""(nuclear speck)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019082""(viral protein processing)|go:""GO:0030877""(beta-catenin destruction complex)|go:""GO:0031670""(cellular response to nutrient)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0051301""(cell division)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050235|mint:P48729|rcsb pdb:5FQD|rcsb pdb:6GZD|rcsb pdb:7WTT|rcsb pdb:8G66|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5635838|reactome:R-HSA-9694631|dip:DIP-40367N|panther:PTHR11909(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q6IAA8	intact:EBI-27055396	intact:EBI-715385|uniprotkb:Q8WZ09|uniprotkb:Q9NWT0|ensembl:ENSP00000278671.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ltor1_human(display_long)|uniprotkb:LAMTOR1(gene name)|psi-mi:LAMTOR1(display_short)|uniprotkb:PP7157(orf name)|uniprotkb:p27Kip1-releasing factor from RhoA(gene name synonym)|uniprotkb:C11orf59(gene name synonym)|uniprotkb:Lipid raft adaptor protein p18(gene name synonym)|uniprotkb:Protein associated with DRMs and endosomes(gene name synonym)|uniprotkb:PDRO(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_060377.1|dip:DIP-39650N|ensembl:ENSG00000149357.10(gene)|ensembl:ENST00000278671.10(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001919""(regulation of receptor recycling)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007032""(endosome organization)|go:""GO:0007040""(lysosome organization)|go:""GO:0008104""(protein localization)|go:""GO:0010874""(regulation of cholesterol efflux)|go:""GO:0016197""(endosomal transport)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0032418""(lysosome localization)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045121""(membrane raft)|go:""GO:0051020""(GTPase binding)|go:""GO:0060620""(regulation of cholesterol import)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071986""(Ragulator complex)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0150032""(positive regulation of protein localization to lysosome)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990877""(FNIP-folliculin RagC/D GAP)|interpro:IPR028209|mint:Q6IAA8|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:6B9X|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|rcsb pdb:6WJ2|rcsb pdb:6WJ3|rcsb pdb:7T3A|rcsb pdb:7T3B|rcsb pdb:7T3C|rcsb pdb:7UX2|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8DHB|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6798695|reactome:R-HSA-8943724|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9639288|panther:PTHR13401(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:qOdH2HiC+MXwRS2+L8/XgkTRDeo9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9Y2A7	intact:EBI-27055396	intact:EBI-389845|uniprotkb:O60329|uniprotkb:Q53QN5|uniprotkb:Q53S94|uniprotkb:Q53Y35|ensembl:ENSP00000355348.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:nckp1_human(display_long)|uniprotkb:NCKAP1(gene name)|psi-mi:NCKAP1(display_short)|uniprotkb:HEM2(gene name synonym)|uniprotkb:KIAA0587(gene name synonym)|uniprotkb:NAP1(gene name synonym)|uniprotkb:p125Nap1(gene name synonym)|uniprotkb:Membrane-associated protein HEM-2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"panther:PTHR12093(orthology-group)|refseq:NP_038464.1|refseq:NP_995314.1|ensembl:ENSG00000061676.16(gene)|ensembl:ENST00000361354.9(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001726""(ruffle)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006915""(apoptotic process)|go:""GO:0007417""(central nervous system development)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031209""(SCAR complex)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031941""(filamentous actin)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000601""(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR019137|mint:Q9Y2A7|rcsb pdb:3P8C|rcsb pdb:4N78|rcsb pdb:7USC|rcsb pdb:7USD|rcsb pdb:7USE|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|dip:DIP-31119N"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:xj4ySr6cf374UbE/gfuxMx1X0tw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P13861	intact:EBI-27055396	intact:EBI-2556122|uniprotkb:Q16823|intact:EBI-6116682|uniprotkb:Q9BUB1|intact:EBI-10961724|ensembl:ENSP00000265563.8|ensembl:ENSP00000394041.1|ensembl:ENSP00000516459.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"dip:DIP-552N|refseq:XP_011532244.1|refseq:NP_004148.1|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:XP_016862304.1|ensembl:ENSG00000114302.17(gene)|ensembl:ENST00000265563.13(transcript)|ensembl:ENST00000454963.5(transcript)|ensembl:ENST00000706574.1(transcript)|go:""GO:0004862""(cAMP-dependent protein kinase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0008603""(cAMP-dependent protein kinase regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030552""(cAMP binding)|go:""GO:0031588""(nucleotide-activated protein kinase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097546""(ciliary base)|go:""GO:0141162""(negative regulation of cAMP/PKA signal transduction)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR050503|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|rcsb pdb:8S8O|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9856530|panther:PTHR11635(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9NZ01	intact:EBI-27055396	intact:EBI-2877718|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55|ensembl:ENSP00000215567.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000099797.15(gene)|ensembl:ENST00000215567.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006665""(sphingolipid metabolic process)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0017099""(very-long-chain fatty acyl-CoA dehydrogenase activity)|go:""GO:0030497""(fatty acid elongation)|go:""GO:0035338""(long-chain fatty-acyl-CoA biosynthetic process)|go:""GO:0042761""(very long-chain fatty acid biosynthetic process)|go:""GO:0102758""(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|interpro:IPR049127|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_001308099.1|refseq:NP_612510.1|efo:""Orphanet:88616""|panther:PTHR10556(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P17301	intact:EBI-27055396	intact:EBI-702960|uniprotkb:Q14595|ensembl:ENSP00000296585.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ita2_human(display_long)|uniprotkb:Platelet membrane glycoprotein Ia(gene name synonym)|uniprotkb:Collagen receptor(gene name synonym)|uniprotkb:VLA-2 subunit alpha(gene name synonym)|uniprotkb:CD49 antigen-like family member B(gene name synonym)|uniprotkb:ITGA2(gene name)|psi-mi:ITGA2(display_short)|uniprotkb:CD49B(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:853""|ensembl:ENSG00000164171.11(gene)|ensembl:ENST00000296585.10(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002687""(positive regulation of leukocyte migration)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006929""(substrate-dependent cell migration)|go:""GO:0006971""(hypotonic response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007565""(female pregnancy)|go:""GO:0007596""(blood coagulation)|go:""GO:0008305""(integrin complex)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0014075""(response to amine)|go:""GO:0014850""(response to muscle activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030879""(mammary gland development)|go:""GO:0031346""(positive regulation of cell projection organization)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0033591""(response to L-ascorbic acid)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0038064""(collagen receptor activity)|go:""GO:0038065""(collagen-activated signaling pathway)|go:""GO:0043236""(laminin binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0043679""(axon terminus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045178""(basal part of cell)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045987""(positive regulation of smooth muscle contraction)|go:""GO:0046872""(metal ion binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050927""(positive regulation of positive chemotaxis)|go:""GO:0050966""(detection of mechanical stimulus involved in sensory perception of pain)|go:""GO:0051971""(positive regulation of transmission of nerve impulse)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0070365""(hepatocyte differentiation)|go:""GO:0071107""(response to parathyroid hormone)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|interpro:IPR048285|interpro:IPR048286|mint:P17301|rcsb pdb:1AOX|rcsb pdb:1DZI|rcsb pdb:1V7P|rcsb pdb:4BJ3|rcsb pdb:5HJ2|rcsb pdb:5THP|rcsb pdb:6ND8|rcsb pdb:6ND9|rcsb pdb:6NDA|rcsb pdb:6NDB|rcsb pdb:6NDC|rcsb pdb:6NDD|rcsb pdb:6NDE|rcsb pdb:6NDF|rcsb pdb:6NDG|rcsb pdb:6NDH|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-447041|reactome:R-HSA-75892|reactome:R-HSA-8874081|refseq:NP_002194.2|dip:DIP-67N|panther:PTHR23220(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:eT9f2vINJKqOgbGP+0BiXcVxiEs9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P18031	intact:EBI-27055396	intact:EBI-968788|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4|ensembl:ENSP00000360683.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N|ensembl:ENSG00000196396.10(gene)|ensembl:ENST00000371621.5(transcript)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0003723""(RNA binding)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0009968""(negative regulation of signal transduction)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030162""(regulation of proteolysis)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031904""(endosome lumen)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033157""(regulation of intracellular protein transport)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035791""(platelet-derived growth factor receptor-beta signaling pathway)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045296""(cadherin binding)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071732""(cellular response to nitric oxide)|go:""GO:0097443""(sorting endosome)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903896""(positive regulation of IRE1-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904753""(negative regulation of vascular associated smooth muscle cell migration)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990264""(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:""GO:2000353""(positive regulation of endothelial cell apoptotic process)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1AAX|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2F6Z|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:2NT7|rcsb pdb:2NTA|rcsb pdb:2QBP|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2QBS|rcsb pdb:2VEU|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2ZMM|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:3EB1|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QDV|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:6OMY|rcsb pdb:6PFW|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:6XE8|rcsb pdb:6XEF|rcsb pdb:6XEA|rcsb pdb:6XED|rcsb pdb:6XEE|rcsb pdb:6XEG|rcsb pdb:7FQM|rcsb pdb:7FQN|rcsb pdb:7FQO|rcsb pdb:7FQP|rcsb pdb:7FQQ|rcsb pdb:7FQR|rcsb pdb:7FQS|rcsb pdb:7FQT|rcsb pdb:7FQU|rcsb pdb:7FQV|rcsb pdb:7FQW|rcsb pdb:7FQX|rcsb pdb:7FQY|rcsb pdb:7FQZ|rcsb pdb:7FRE|rcsb pdb:7FRF|rcsb pdb:7FRG|rcsb pdb:7FRH|rcsb pdb:7FRI|rcsb pdb:7FRJ|rcsb pdb:7FRK|rcsb pdb:7FRL|rcsb pdb:7FRM|rcsb pdb:7FRN|rcsb pdb:7FRO|rcsb pdb:7FRP|rcsb pdb:7FRQ|rcsb pdb:7FRR|rcsb pdb:7FRS|rcsb pdb:7FRT|rcsb pdb:7FRU|rcsb pdb:7GS7|rcsb pdb:7GS8|rcsb pdb:7GS9|rcsb pdb:7GSA|rcsb pdb:7GSB|rcsb pdb:7GSC|rcsb pdb:7GSD|rcsb pdb:7GSE|rcsb pdb:7GSF|rcsb pdb:7GSG|rcsb pdb:7GSH|rcsb pdb:7GSI|rcsb pdb:7GSJ|rcsb pdb:7GSK|rcsb pdb:7GSL|rcsb pdb:7GSM|rcsb pdb:7GSN|rcsb pdb:7GSO|rcsb pdb:7GSQ|rcsb pdb:7GSR|rcsb pdb:7GST|rcsb pdb:7GSU|rcsb pdb:7GSV|rcsb pdb:7GSW|rcsb pdb:7GSX|rcsb pdb:7GSY|rcsb pdb:7GSZ|rcsb pdb:7GT0|rcsb pdb:7GT1|rcsb pdb:7GT2|rcsb pdb:7GT3|rcsb pdb:7GT4|rcsb pdb:7GT5|rcsb pdb:7GTI|rcsb pdb:7GT6|rcsb pdb:7GT7|rcsb pdb:7GT8|rcsb pdb:7GT9|rcsb pdb:7GTA|rcsb pdb:7GTB|rcsb pdb:7GTC|rcsb pdb:7GTD|rcsb pdb:7GTE|rcsb pdb:7GTF|rcsb pdb:7GTG|rcsb pdb:7GTH|rcsb pdb:7GTJ|rcsb pdb:7GTK|rcsb pdb:7GTL|rcsb pdb:7GTM|rcsb pdb:7GTN|rcsb pdb:7GTO|rcsb pdb:7GTP|rcsb pdb:7GTQ|rcsb pdb:7GTR|rcsb pdb:7GTS|rcsb pdb:7GTT|rcsb pdb:7GTU|rcsb pdb:7GTV|rcsb pdb:7GTW|rcsb pdb:7GTX|rcsb pdb:7GTY|rcsb pdb:7GTZ|rcsb pdb:7GU0|rcsb pdb:7GU1|rcsb pdb:7GU2|rcsb pdb:7GU3|rcsb pdb:7GU4|rcsb pdb:7GU5|rcsb pdb:7GU6|rcsb pdb:7GU7|rcsb pdb:7GU8|rcsb pdb:7GU9|rcsb pdb:7GUA|rcsb pdb:7GUB|rcsb pdb:7GUC|rcsb pdb:7KEN|rcsb pdb:7KEY|rcsb pdb:7KLX|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MKZ|rcsb pdb:7MM1|rcsb pdb:7MN7|rcsb pdb:7MN9|rcsb pdb:7MNA|rcsb pdb:7MNB|rcsb pdb:7MNC|rcsb pdb:7MND|rcsb pdb:7MNE|rcsb pdb:7MNF|rcsb pdb:7MOU|rcsb pdb:7MOV|rcsb pdb:7MOW|rcsb pdb:7RIN|rcsb pdb:7S4F|rcsb pdb:8DU7|rcsb pdb:8EXI|rcsb pdb:8EXJ|rcsb pdb:8EXK|rcsb pdb:8EXM|rcsb pdb:8EXN|rcsb pdb:8EYA|rcsb pdb:8EYB|rcsb pdb:8EYC|rcsb pdb:8F88|rcsb pdb:8G65|rcsb pdb:8G67|rcsb pdb:8G68|rcsb pdb:8G69|rcsb pdb:8G6A|rcsb pdb:8SKL|rcsb pdb:8U1E|rcsb pdb:8XOY|rcsb pdb:9C66|rcsb pdb:9CYO|rcsb pdb:9CYP|rcsb pdb:9CYQ|rcsb pdb:9CYR|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-77387|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-9860927|panther:PTHR46047(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P04844	intact:EBI-27055396	intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530.6|ensembl:ENSP00000517679.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001129243.1|refseq:NP_002942.2|refseq:NP_001311235.1|refseq:NP_001311234.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1|ensembl:ENSG00000118705.18(gene)|ensembl:ENSG00000291973.1(gene)|ensembl:ENST00000237530.11(transcript)|ensembl:ENST00000709412.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0036211""(protein modification process)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|panther:PTHR12640(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q92783	intact:EBI-27055396	intact:EBI-752333|ensembl:ENSP00000366746.3|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000136738.15(gene)|ensembl:ENST00000377524.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0016236""(macroautophagy)|go:""GO:0031901""(early endosome membrane)|go:""GO:0033565""(ESCRT-0 complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0090148""(membrane fission)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903551""(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|interpro:IPR047492|interpro:IPR047528|interpro:IPR050670|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|refseq:NP_003464.1|dip:DIP-37761N|panther:PTHR45929(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P07947	intact:EBI-27055396	intact:EBI-515331|uniprotkb:A6NLB3|uniprotkb:D3DUH1|ensembl:ENSP00000324740.4|ensembl:ENSP00000462468.1|intact:EBI-28995389	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:yes_human(display_long)|uniprotkb:p61-Yes(gene name synonym)|uniprotkb:Proto-oncogene c-Yes(gene name synonym)|uniprotkb:YES1(gene name)|psi-mi:YES1(display_short)|uniprotkb:YES(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:XP_016881449.1|refseq:NP_005424.1|ensembl:ENSG00000176105.14(gene)|ensembl:ENST00000314574.5(transcript)|ensembl:ENST00000584307.5(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0010827""(regulation of D-glucose transmembrane transport)|go:""GO:0019899""(enzyme binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031295""(T cell costimulation)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036211""(protein modification process)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0043114""(regulation of vascular permeability)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050900""(leukocyte migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0140801""(histone H2AXY142 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035751|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P07947|rcsb pdb:2HDA|reactome:R-HSA-1227986|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2682334|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-8940973|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9680350|dip:DIP-33849N|panther:PTHR24418(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:Wo+NWxPVSmF8W6ZHQmTPpg3YuY09606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P54709	intact:EBI-27055396	intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001670.1|dip:DIP-50717N|ensembl:ENSG00000069849.11(gene)|ensembl:ENST00000286371.8(transcript)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042470""(melanosome)|go:""GO:0050821""(protein stabilization)|go:""GO:0051117""(ATPase binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071805""(potassium ion transmembrane transport)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0086009""(membrane repolarization)|go:""GO:1901018""(positive regulation of potassium ion transmembrane transporter activity)|go:""GO:1903278""(positive regulation of sodium ion export across plasma membrane)|go:""GO:1903288""(positive regulation of potassium ion import across plasma membrane)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|panther:PTHR11523(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q03135	intact:EBI-27055396	intact:EBI-603614|uniprotkb:Q9UGP1|uniprotkb:Q9UNG1|uniprotkb:Q9UQH6|ensembl:ENSP00000339191.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:cav1_human(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.47	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000105974.13(gene)|ensembl:ENST00000341049.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001525""(angiogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0001960""(negative regulation of cytokine-mediated signaling pathway)|go:""GO:0002067""(glandular epithelial cell differentiation)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0002095""(caveolar macromolecular signaling complex)|go:""GO:0002931""(response to ischemia)|go:""GO:0003057""(regulation of the force of heart contraction by chemical signal)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005113""(patched binding)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0005938""(cell cortex)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006940""(regulation of smooth muscle contraction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007595""(lactation)|go:""GO:0008104""(protein localization)|go:""GO:0008142""(oxysterol binding)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009617""(response to bacterium)|go:""GO:0010524""(positive regulation of calcium ion transport into cytosol)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0015031""(protein transport)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0016050""(vesicle organization)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0019065""(receptor-mediated endocytosis of virus by host cell)|go:""GO:0019217""(regulation of fatty acid metabolic process)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019915""(lipid storage)|go:""GO:0030154""(cell differentiation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030857""(negative regulation of epithelial cell differentiation)|go:""GO:0030879""(mammary gland development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032507""(maintenance of protein location in cell)|go:""GO:0032570""(response to progesterone)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033484""(intracellular nitric oxide homeostasis)|go:""GO:0034141""(positive regulation of toll-like receptor 3 signaling pathway)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038166""(angiotensin-activated signaling pathway)|go:""GO:0042310""(vasoconstriction)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043627""(response to estrogen)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044860""(protein localization to plasma membrane raft)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045019""(negative regulation of nitric oxide biosynthetic process)|go:""GO:0045121""(membrane raft)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048550""(negative regulation of pinocytosis)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051899""(membrane depolarization)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060355""(positive regulation of cell adhesion molecule production)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070320""(inward rectifier potassium channel inhibitor activity)|go:""GO:0070836""(caveola assembly)|go:""GO:0071218""(cellular response to misfolded protein)|go:""GO:0071360""(cellular response to exogenous dsRNA)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0071455""(cellular response to hyperoxia)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0098903""(regulation of membrane repolarization during action potential)|go:""GO:0098909""(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900027""(regulation of ruffle assembly)|go:""GO:1901380""(negative regulation of potassium ion transmembrane transport)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1903598""(positive regulation of gap junction assembly)|go:""GO:1903609""(negative regulation of inward rectifier potassium channel activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000535""(regulation of entry of bacterium into host cell)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR018361|mint:Q03135|rcsb pdb:7SC0|reactome:R-HSA-163560|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-210991|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9617828|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001744.2|dip:DIP-5960N|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:275777""|efo:""Orphanet:528""|panther:PTHR10844(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:+JhGp5YmhT3JLeTgHHBTHu9r34c9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8TBA6	intact:EBI-27055396	intact:EBI-11278147|uniprotkb:O95287|uniprotkb:Q03962|uniprotkb:Q2TS49|uniprotkb:Q9UQQ7|uniprotkb:C9JRU1|ensembl:ENSP00000163416.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:goga5_human(display_long)|uniprotkb:GOLGA5(gene name)|psi-mi:GOLGA5(display_short)|uniprotkb:Cell proliferation-inducing gene 31 protein(gene name synonym)|uniprotkb:Golgin-84(gene name synonym)|uniprotkb:Protein Ret-II(gene name synonym)|uniprotkb:RET-fused gene 5 protein(gene name synonym)|uniprotkb:RETII(gene name synonym)|uniprotkb:RFG5(gene name synonym)|uniprotkb:PIG31(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:146""|ensembl:ENSG00000066455.13(gene)|ensembl:ENST00000163416.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000301""(retrograde transport, vesicle recycling within Golgi)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0007030""(Golgi organization)|go:""GO:0016020""(membrane)|go:""GO:0030133""(transport vesicle)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031985""(Golgi cisterna)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048193""(Golgi vesicle transport)|interpro:IPR019177|mint:Q8TBA6|reactome:R-HSA-6811438|refseq:NP_005104.3|refseq:XP_011535722.1|panther:PTHR13815(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:PtiO2qhE4u4CFxYqL+bqph4lmT09606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9HAU0	intact:EBI-27055396	intact:EBI-945934|uniprotkb:Q86ST7|uniprotkb:A0JP03|uniprotkb:Q8N3K6|uniprotkb:Q96DY9|uniprotkb:Q9BVR4|uniprotkb:Q9C0H7|uniprotkb:Q9H924|uniprotkb:Q9NVK8|uniprotkb:B4DGS1|uniprotkb:F5H0I0|uniprotkb:E9PHQ3|uniprotkb:Q6NSF8|ensembl:ENSP00000299275.6	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:pkha5_human(display_long)|uniprotkb:PLEKHA5(gene name)|psi-mi:PLEKHA5(display_short)|uniprotkb:KIAA1686(gene name synonym)|uniprotkb:PEPP2(gene name synonym)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001137293.2|refseq:NP_061885.2|refseq:NP_001177789.2|refseq:NP_001243399.1|refseq:NP_001243716.1|refseq:XP_005253457.1|ensembl:ENSG00000052126.17(gene)|ensembl:ENST00000299275.10(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0010314""(phosphatidylinositol-5-phosphate binding)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0061458""(reproductive system development)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0080025""(phosphatidylinositol-3,5-bisphosphate binding)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|mint:Q9HAU0|rcsb pdb:2DKP|reactome:R-HSA-1660499|refseq:XP_016874992.1|refseq:XP_011519019.1|panther:PTHR12752(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:22W2zdIwTLw4nNRh0dHasYDCLK49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P78504	intact:EBI-27055396	intact:EBI-2847071|uniprotkb:O14902|uniprotkb:A0AV43|uniprotkb:O15122|uniprotkb:Q15816|uniprotkb:B4DYR1|uniprotkb:E9PCF9|ensembl:ENSP00000254958.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:jag1_human(display_long)|uniprotkb:JAG1(gene name)|psi-mi:JAG1(display_short)|uniprotkb:JAGL1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000101384.12(gene)|ensembl:ENST00000254958.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001709""(cell fate determination)|go:""GO:0001953""(negative regulation of cell-matrix adhesion)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0002085""(inhibition of neuroepithelial cell differentiation)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003215""(cardiac right ventricle morphogenesis)|go:""GO:0005112""(Notch binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008083""(growth factor activity)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0035909""(aorta morphogenesis)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042491""(inner ear auditory receptor cell differentiation)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045446""(endothelial cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045602""(negative regulation of endothelial cell differentiation)|go:""GO:0045639""(positive regulation of myeloid cell differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050678""(regulation of epithelial cell proliferation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0061073""(ciliary body morphogenesis)|go:""GO:0061101""(neuroendocrine cell differentiation)|go:""GO:0061156""(pulmonary artery morphogenesis)|go:""GO:0061309""(cardiac neural crest cell development involved in outflow tract morphogenesis)|go:""GO:0061444""(endocardial cushion cell development)|go:""GO:0062043""(positive regulation of cardiac epithelial to mesenchymal transition)|go:""GO:0072006""(nephron development)|go:""GO:0072015""(podocyte development)|go:""GO:0072017""(distal tubule development)|go:""GO:0072070""(loop of Henle development)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:2000737""(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001774(""Delta/Serrate/lag-2 (DSL) protein"")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026219|interpro:IPR049883|mint:P78504|rcsb pdb:2KB9|rcsb pdb:2VJ2|rcsb pdb:4CBZ|rcsb pdb:4CC0|rcsb pdb:4CC1|rcsb pdb:4XI7|rcsb pdb:5BO1|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-8941856|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9013507|reactome:R-HSA-9013700|reactome:R-HSA-9831926|refseq:NP_000205.1|refseq:XP_016883196.1|dip:DIP-46371N|efo:""Orphanet:261600""|efo:""Orphanet:261619""|efo:""Orphanet:3303""|panther:PTHR24044(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:kaBPZjsO7mchlR6vYIknqvTluos9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8NDI1	intact:EBI-27055396	intact:EBI-2689720|uniprotkb:Q9NWI9|uniprotkb:Q6QNV2|uniprotkb:Q6NX72|uniprotkb:Q53TV6|uniprotkb:Q6PIT3|uniprotkb:Q53TG7|uniprotkb:Q580X2|uniprotkb:O94977|ensembl:ENSP00000263991.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ehbp1_human(display_long)|uniprotkb:KIAA0903(gene name synonym)|uniprotkb:NACSIN(gene name synonym)|uniprotkb:EHBP1(gene name)|psi-mi:EHBP1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:XP_011531015.1|refseq:XP_011531016.1|refseq:XP_011531017.1|refseq:NP_001136086.1|refseq:NP_001136087.1|refseq:NP_001136088.1|refseq:NP_056067.2|refseq:XP_016859136.1|refseq:XP_016859137.1|refseq:XP_016859138.1|refseq:XP_005264282.1|refseq:XP_005264283.1|refseq:XP_005264284.1|rcsb pdb:6ZSJ|ensembl:ENSG00000115504.15(gene)|ensembl:ENST00000263991.9(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0015031""(protein transport)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR019448|interpro:IPR022735|interpro:IPR036872|interpro:IPR050540|mint:Q8NDI1|rcsb pdb:2D89|rcsb pdb:6ZSH|rcsb pdb:6ZSI|refseq:XP_016859132.1|refseq:XP_016859133.1|refseq:XP_016859140.1|panther:PTHR23167(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:sDcegXBYi8eQp7KReaysxBy3Ogc9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q02487	intact:EBI-27055396	intact:EBI-3048545|ensembl:ENSP00000280904.6	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:dsc2_human(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:CDHF2(gene name synonym)|uniprotkb:DSC3(gene name synonym)|uniprotkb:Cadherin family member 2(gene name synonym)|uniprotkb:Desmocollin-3(gene name synonym)|uniprotkb:Desmosomal glycoprotein II(gene name synonym)|uniprotkb:Desmosomal glycoprotein III(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000134755.19(gene)|ensembl:ENST00000280904.11(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0014704""(intercalated disc)|go:""GO:0030057""(desmosome)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0086042""(cardiac muscle cell-cardiac muscle cell adhesion)|go:""GO:0086073""(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:""GO:0086083""(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:1900745""(positive regulation of p38MAPK cascade)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR050971|mint:Q02487|rcsb pdb:5ERP|rcsb pdb:5J5J|rcsb pdb:7A7D|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_004940.1|refseq:NP_077740.1|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|panther:PTHR24025(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:EUXe5KbkWaO5wRalhRX+pf7jkOQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q5T2T1	intact:EBI-27055396	intact:EBI-2514004|uniprotkb:B2RCC9|uniprotkb:Q5T2T0|uniprotkb:B5MDZ3|uniprotkb:Q8IY28|uniprotkb:D3DRW3|uniprotkb:B4DWL9|ensembl:ENSP00000337907.5|ensembl:ENSP00000364871.3|ensembl:ENSP00000364884.1|ensembl:ENSP00000507917.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:mpp7_human(display_long)|uniprotkb:MPP7(gene name)|psi-mi:MPP7(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:XP_011517639.1|refseq:NP_775767.2|refseq:NP_001305099.1|ensembl:ENSG00000150054.19(gene)|ensembl:ENST00000337532.9(transcript)|ensembl:ENST00000375719.7(transcript)|ensembl:ENST00000375732.5(transcript)|ensembl:ENST00000683449.1(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005938""(cell cortex)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030054""(cell junction)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0097025""(MPP7-DLG1-LIN7 complex)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035599|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|interpro:IPR050716|mint:Q5T2T1|rcsb pdb:3LRA|rcsb pdb:3O46|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|panther:PTHR23122(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:QYVCkD5zsnTsCd7YsYsbQY8L7fU9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q15043	intact:EBI-27055396	intact:EBI-6116466|uniprotkb:A6NH98|uniprotkb:B4DIW3|uniprotkb:B6EU88|uniprotkb:D3DSR4|uniprotkb:Q6ZME8|uniprotkb:Q96BB3|ensembl:ENSP00000289952.5|ensembl:ENSP00000370635.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:s39ae_human(display_long)|uniprotkb:SLC39A14(gene name)|psi-mi:SLC39A14(display_short)|uniprotkb:KIAA0062(gene name synonym)|uniprotkb:ZIP14(gene name synonym)|uniprotkb:LIV-1 subfamily of ZIP zinc transporter 4(gene name synonym)|uniprotkb:Solute carrier family 39 member 14(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 14(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000104635.15(gene)|ensembl:ENST00000289952.9(transcript)|ensembl:ENST00000381237.6(transcript)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0005381""(iron ion transmembrane transporter activity)|go:""GO:0005384""(manganese ion transmembrane transporter activity)|go:""GO:0005385""(zinc ion transmembrane transporter activity)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0010817""(regulation of hormone levels)|go:""GO:0015086""(cadmium ion transmembrane transporter activity)|go:""GO:0015093""(ferrous iron transmembrane transporter activity)|go:""GO:0015296""(""monoatomic anion:monoatomic cation symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030003""(intracellular monoatomic cation homeostasis)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0033212""(iron import into cell)|go:""GO:0034755""(iron ion transmembrane transport)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0055071""(manganese ion homeostasis)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071421""(manganese ion transmembrane transport)|go:""GO:0071577""(zinc ion transmembrane transport)|go:""GO:0071578""(zinc ion import across plasma membrane)|go:""GO:0098662""(inorganic cation transmembrane transport)|go:""GO:0098739""(import across plasma membrane)|go:""GO:0140410""(""monoatomic cation:bicarbonate symporter activity"")|interpro:IPR003689(Zinc/iron permease)|interpro:IPR050799|mint:Q15043|reactome:R-HSA-442380|refseq:NP_001121903.1|refseq:NP_001128625.1|refseq:NP_056174.2|refseq:XP_005273522.1|refseq:XP_005273523.1|refseq:XP_006716387.1|refseq:XP_011542780.1|refseq:XP_016868783.1|refseq:XP_016868784.1|efo:""Orphanet:521406""|panther:PTHR12191(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:tpJl2FORU2if7SOPN8ZDwPvF+HM9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O60493	intact:EBI-27055396	intact:EBI-727209|uniprotkb:Q4TT31|uniprotkb:O60718|uniprotkb:Q5JXJ7|uniprotkb:Q5JXJ8|uniprotkb:Q96AP9|uniprotkb:Q9C0J5|uniprotkb:Q9NU45|intact:EBI-1056609|uniprotkb:A8K0B1|uniprotkb:Q4TT29|uniprotkb:E1P5E4|uniprotkb:E1P5E5|ensembl:ENSP00000230085.8	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:snx3_human(display_long)|uniprotkb:Protein SDP3(gene name synonym)|uniprotkb:SNX3(gene name)|psi-mi:SNX3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_003786.1|refseq:NP_690040.1|ensembl:ENSG00000112335.15(gene)|ensembl:ENST00000230085.13(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0009617""(response to bacterium)|go:""GO:0010008""(endosome membrane)|go:""GO:0010314""(phosphatidylinositol-5-phosphate binding)|go:""GO:0010324""(membrane invagination)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0015031""(protein transport)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022615""(protein to membrane docking)|go:""GO:0030111""(regulation of Wnt signaling pathway)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030904""(retromer complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032009""(early phagosome)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0034499""(late endosome to Golgi transport)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051224""(negative regulation of protein transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070676""(intralumenal vesicle formation)|go:""GO:0080025""(phosphatidylinositol-3,5-bisphosphate binding)|go:""GO:1905394""(retromer complex binding)|go:""GO:2000642""(negative regulation of early endosome to late endosome transport)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR042137|interpro:IPR051074|mint:O60493|rcsb pdb:2MXC|rcsb pdb:2YPS|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:7BLO|reactome:R-HSA-3238698|reactome:R-HSA-5689880|refseq:NP_001287858.1|panther:PTHR45963(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:M/QKs79zhWobkEdFuxrJTnrrUes9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q96AG4	intact:EBI-27055396	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|uniprotkb:B2RE83|ensembl:ENSP00000225972.7	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_060979.2|ensembl:ENSG00000108829.10(gene)|ensembl:ENST00000225972.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045296""(cadherin binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050216|mint:Q96AG4|panther:PTHR45752(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q6WCQ1	intact:EBI-27055396	intact:EBI-1022605|uniprotkb:Q3KQZ5|uniprotkb:Q5FB94|uniprotkb:Q6DHW2|uniprotkb:Q7Z5Y2|uniprotkb:Q8N390|uniprotkb:Q96G40|ensembl:ENSP00000342379.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:mprip_human(display_long)|uniprotkb:MRIP(gene name synonym)|uniprotkb:Rho-interacting protein 3(gene name synonym)|uniprotkb:p116Rip(gene name synonym)|uniprotkb:MPRIP(gene name)|psi-mi:MPRIP(display_short)|uniprotkb:KIAA0864(gene name synonym)|uniprotkb:RHOIP3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_055949.2|refseq:NP_958431.2|ensembl:ENSG00000133030.22(gene)|ensembl:ENST00000341712.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0045296""(cadherin binding)|go:""GO:0051015""(actin filament binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|interpro:IPR052223|mint:Q6WCQ1|reactome:R-HSA-6802952|panther:PTHR17271(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:QoGbbg2ehuQogDM1Dlxzw6xj59s9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q01974	intact:EBI-27055396	intact:EBI-6422642|ensembl:ENSP00000364860.3|uniprotkb:Q59GF5|uniprotkb:Q9HB61|uniprotkb:Q9HAY7|uniprotkb:Q5SPI5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ror2_human(display_long)|uniprotkb:NTRKR2(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase, receptor-related 2(gene name synonym)|uniprotkb:ROR2(gene name)|psi-mi:ROR2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000169071.15(gene)|ensembl:ENST00000375708.4(transcript)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009986""(cell surface)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014002""(astrocyte development)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0030282""(bone mineralization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030539""(male genitalia development)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043235""(receptor complex)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051968""(positive regulation of synaptic transmission, glutamatergic)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0150045""(regulation of synaptic signaling by nitric oxide)|go:""GO:1905517""(macrophage migration)|interpro:IPR000001(Kringle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR016247(Tyrosine-protein kinase transmembrane receptor ROR)|interpro:IPR018056|interpro:IPR020067|interpro:IPR036179|interpro:IPR036790|interpro:IPR038178|interpro:IPR050122|mint:Q01974|rcsb pdb:3ZZW|rcsb pdb:4GT4|rcsb pdb:6OSH|rcsb pdb:6OSN|rcsb pdb:6OSV|rcsb pdb:9FSE|reactome:R-HSA-4086400|reactome:R-HSA-5140745|refseq:NP_001305133.1|refseq:NP_004551.2|efo:""Orphanet:1507""|efo:""Orphanet:572385""|panther:PTHR24416(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:gEEAvjiYUC5dWEtyCE0eb0K+MTU9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q99618	intact:EBI-27055396	intact:EBI-739534|uniprotkb:A8K5V6|uniprotkb:D3DUS6|ensembl:ENSP00000442068.1|ensembl:ENSP00000446339.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:cdca3_human(display_long)|uniprotkb:CDCA3(gene name)|psi-mi:CDCA3(display_short)|uniprotkb:Trigger of mitotic entry protein 1(gene name synonym)|uniprotkb:Gene-rich cluster protein C8(gene name synonym)|uniprotkb:C8(gene name synonym)|uniprotkb:GRCC8(gene name synonym)|uniprotkb:TOME1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_112589.1|ensembl:ENSG00000111665.12(gene)|ensembl:ENST00000535406.5(transcript)|ensembl:ENST00000538862.7(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005912""(adherens junction)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0051301""(cell division)|interpro:IPR038832|mint:Q99618|refseq:NP_001284532.1|refseq:NP_001284533.1|refseq:NP_001317948.1|panther:PTHR34756(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:UmhACVP83jo9/xqP7qDSSvKgiAo9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9BVP2	intact:EBI-27055396	intact:EBI-641642|uniprotkb:Q96SV6|uniprotkb:Q96SV7|uniprotkb:Q9UJY0|intact:EBI-2559594|intact:EBI-718302|uniprotkb:B2RDC1|uniprotkb:Q5PU80|intact:EBI-28973725|ensembl:ENSP00000395772.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:gnl3_human(display_long)|uniprotkb:Nucleolar GTP-binding protein 3(gene name synonym)|uniprotkb:Nucleostemin(gene name synonym)|uniprotkb:E2-induced gene 3 protein(gene name synonym)|uniprotkb:Novel nucleolar protein 47(gene name synonym)|uniprotkb:GNL3(gene name)|psi-mi:GNL3(display_short)|uniprotkb:E2IG3(gene name synonym)|uniprotkb:NS(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_055181.3|refseq:NP_996561.1|refseq:NP_996562.1|ensembl:ENSG00000163938.17(gene)|ensembl:ENST00000418458.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0017145""(stem cell division)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0030496""(midbody)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0033235""(positive regulation of protein sumoylation)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904816""(positive regulation of protein localization to chromosome, telomeric region)|interpro:IPR006073(GTP1/OBG)|interpro:IPR014813(GNL3L/Grn1 putative GTPase)|interpro:IPR027417|interpro:IPR030378|interpro:IPR050755|mint:Q9BVP2|rcsb pdb:8FKP|rcsb pdb:8FKR|rcsb pdb:8FKT|rcsb pdb:8FKU|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|rcsb pdb:8FKZ|rcsb pdb:8FL0|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8INK|rcsb pdb:8IPD|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR1|rcsb pdb:8IR3|reactome:R-HSA-6791226|panther:PTHR11089(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:c1DgvQoZ51edxvnCa6GFhfNRR7M9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8IZP0	intact:EBI-27055396	intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6|ensembl:ENSP00000365312.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|refseq:NP_001171596.1|refseq:NP_001171587.1|ensembl:ENSG00000136754.18(gene)|ensembl:ENST00000376142.6(transcript)|go:""GO:0001756""(somitogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0014069""(postsynaptic density)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030426""(growth cone)|go:""GO:0031209""(SCAR complex)|go:""GO:0032433""(filopodium tip)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0045296""(cadherin binding)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:0098858""(actin-based cell projection)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|rcsb pdb:7LXE|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|dip:DIP-31118N|panther:PTHR10460(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q07960	intact:EBI-27055396	intact:EBI-602762|uniprotkb:D3DQQ6|ensembl:ENSP00000310491.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:rhg01_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-related small GTPase protein activator(gene name synonym)|uniprotkb:p50-RhoGAP(gene name synonym)|uniprotkb:CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP1(gene name)|psi-mi:ARHGAP1(display_short)|uniprotkb:CDC42GAP(gene name synonym)|uniprotkb:RHOGAP1(gene name synonym)|uniprotkb:GTPase-activating protein rhoGAP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_004299.1|ensembl:ENSG00000175220.12(gene)|ensembl:ENST00000311956.9(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0010008""(endosome membrane)|go:""GO:0016197""(endosomal transport)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0033572""(transferrin transport)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0070062""(extracellular exosome)|reactome:R-HSA-9696270|go:""GO:2001136""(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|interpro:IPR049592|mint:Q07960|rcsb pdb:1AM4|rcsb pdb:1GRN|rcsb pdb:1OW3|rcsb pdb:1RGP|rcsb pdb:1TX4|rcsb pdb:2NGR|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:6R3V|rcsb pdb:7QSC|rcsb pdb:7QTM|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|refseq:XP_011518397.1|dip:DIP-6081N|panther:PTHR45808(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:ceA3oLsnddhLiSbylS89P64mYBo9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P04439	intact:EBI-27055396	intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155|ensembl:ENSP00000366005.5|ensembl:ENSP00000379873.1|ensembl:ENSP00000516612.1|ensembl:ENSP00000516614.1|ensembl:ENSP00000516616.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"efo:""Orphanet:179""|ensembl:ENSG00000206503.15(gene)|ensembl:ENST00000376809.10(transcript)|ensembl:ENST00000396634.5(transcript)|ensembl:ENST00000706901.1(transcript)|ensembl:ENST00000706903.1(transcript)|ensembl:ENST00000706905.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002419""(T cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002485""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0003723""(RNA binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0062061""(TAP complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2000568""(positive regulation of memory T cell activation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WJ5|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7MLE|rcsb pdb:7PHR|rcsb pdb:7QPD|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7STF|rcsb pdb:7UC5|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|rcsb pdb:8DVG|rcsb pdb:8RYM|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_001229687.1|refseq:NP_002107.3|ensembl:ENSP00000366005.5|ensembl:ENSP00000379873.1|ensembl:ENSP00000516612.1|ensembl:ENSP00000516614.1|ensembl:ENSP00000516616.1|panther:PTHR16675(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P49006	intact:EBI-27055396	intact:EBI-4289961|uniprotkb:Q5TEE6|uniprotkb:Q6NXS5|uniprotkb:D3DPQ0|ensembl:ENSP00000362638.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:mrp_human(display_long)|uniprotkb:MARCKSL1(gene name)|psi-mi:MARCKSL1(display_short)|uniprotkb:MLP(gene name synonym)|uniprotkb:MRP(gene name synonym)|uniprotkb:MARCKS-like protein 1(gene name synonym)|uniprotkb:Macrophage myristoylated alanine-rich C kinase substrate(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_075385.1|ensembl:ENSG00000175130.7(gene)|ensembl:ENST00000329421.8(transcript)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0007015""(actin filament organization)|go:""GO:0007417""(central nervous system development)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P49006|panther:PTHR14353(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:nkq8hGJINvCHlZJ3alKkDP+wCxk9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P80723	intact:EBI-27055396	intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281.3|ensembl:ENSP00000482066.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788.9(gene)|ensembl:ENST00000322611.4(transcript)|ensembl:ENST00000616743.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0007356""(thorax and anterior abdomen determination)|go:""GO:0008406""(gonad development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016605""(PML body)|go:""GO:0016607""(nuclear speck)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030054""(cell junction)|go:""GO:0030426""(growth cone)|go:""GO:0031982""(vesicle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0060231""(mesenchymal to epithelial transition)|go:""GO:0060421""(positive regulation of heart growth)|go:""GO:0060539""(diaphragm development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072075""(metanephric mesenchyme development)|go:""GO:0072112""(podocyte differentiation)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:2001076""(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034|panther:PTHR23212(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:X+L20HKimV3J+vLnQljg+x78+e09606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:O00213	intact:EBI-27055396	intact:EBI-81694|uniprotkb:Q96A93|uniprotkb:A6NH82|uniprotkb:A6NL69|ensembl:ENSP00000477213.1|uniprotkb:D3DQT2|uniprotkb:B7Z2Y0|uniprotkb:A1E379|uniprotkb:B7Z1J5|uniprotkb:B7Z1J6|uniprotkb:Q7Z324|uniprotkb:V9GYK0|uniprotkb:V9GYT4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:apbb1_human(display_long)|uniprotkb:APBB1(gene name)|psi-mi:APBB1(display_short)|uniprotkb:FE65(gene name synonym)|uniprotkb:RIR(gene name synonym)|uniprotkb:Protein Fe65(gene name synonym)|uniprotkb:Amyloid-beta A4 precursor protein-binding family B member 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001244254.1|refseq:XP_016873130.1|ensembl:ENSG00000166313.20(gene)|ensembl:ENST00000609360.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006325""(chromatin organization)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006915""(apoptotic process)|go:""GO:0006939""(smooth muscle contraction)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0007409""(axonogenesis)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016607""(nuclear speck)|go:""GO:0030027""(lamellipodium)|go:""GO:0030426""(growth cone)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042393""(histone binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045202""(synapse)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070064""(proline-rich region binding)|go:""GO:1902807""(negative regulation of cell cycle G1/S phase transition)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR039576|mint:O00213|rcsb pdb:2E45|rcsb pdb:2HO2|rcsb pdb:2IDH|rcsb pdb:2OEI|rcsb pdb:3D8D|rcsb pdb:3D8E|rcsb pdb:3D8F|rcsb pdb:3DXC|rcsb pdb:3DXD|rcsb pdb:3DXE|rcsb pdb:5NQH|reactome:R-HSA-5693565|refseq:NP_001244248.1|refseq:NP_001155.1|refseq:NP_663722.1|refseq:NP_001244252.1|refseq:NP_001244255.1|panther:PTHR14058(orthology-group)|refseq:NP_001244249.1|refseq:NP_001244250.1|refseq:XP_011518342.1|dip:DIP-30903N"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:3vC/0PYrQRCoZLpyDN1xhXmVsD89606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P23229	intact:EBI-27055396	intact:EBI-2436548|uniprotkb:Q9UCT1|uniprotkb:B2RMU9|uniprotkb:B4DG69|uniprotkb:B4DKB8|uniprotkb:Q08443|uniprotkb:Q0MRC7|uniprotkb:Q14646|uniprotkb:Q16508|uniprotkb:Q53RX7|uniprotkb:Q59HB7|uniprotkb:Q86VL6|uniprotkb:Q9UN03|uniprotkb:G5E9H1|uniprotkb:C4AM96|ensembl:ENSP00000406694.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ita6_human(display_long)|uniprotkb:ITGA6(gene name)|psi-mi:ITGA6(display_short)|uniprotkb:VLA-6(gene name synonym)|uniprotkb:CD49 antigen-like family member F(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000091409.17(gene)|ensembl:ENST00000442250.6(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010668""(ectodermal cell differentiation)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0030175""(filopodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0031994""(insulin-like growth factor I binding)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034675""(integrin alpha6-beta1 complex)|go:""GO:0034676""(integrin alpha6-beta4 complex)|go:""GO:0035878""(nail development)|go:""GO:0038132""(neuregulin binding)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043236""(laminin binding)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0050900""(leukocyte migration)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR048285|interpro:IPR048286|mint:P23229|rcsb pdb:7CEB|rcsb pdb:7CEC|reactome:R-HSA-2022090|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|reactome:R-HSA-9725554|refseq:NP_000201.2|refseq:NP_001073286.1|refseq:NP_001303235.1|efo:""Orphanet:79403""|panther:PTHR23220(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:YyoW/gnP6QH8w7M9UxzVxMTkpOg9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P07948	intact:EBI-27055396	intact:EBI-79452|uniprotkb:A0AVQ5|intact:EBI-6868890|ensembl:ENSP00000428924.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lyn_human(display_long)|uniprotkb:JTK8(gene name synonym)|uniprotkb:Lck/Yes-related novel protein tyrosine kinase(gene name synonym)|uniprotkb:V-yes-1 Yamaguchi sarcoma viral related oncogene homolog(gene name synonym)|uniprotkb:p53Lyn(gene name synonym)|uniprotkb:p56Lyn(gene name synonym)|uniprotkb:LYN(gene name)|psi-mi:LYN(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001104567.1|refseq:NP_002341.1|panther:PTHR24418(orthology-group)|refseq:XP_016868905.1|dip:DIP-1056N|ensembl:ENSG00000254087.8(gene)|ensembl:ENST00000519728.6(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002431""(Fc receptor mediated stimulatory signaling pathway)|go:""GO:0002513""(tolerance induction to self antigen)|go:""GO:0002553""(histamine secretion by mast cell)|go:""GO:0002576""(platelet degranulation)|go:""GO:0002762""(negative regulation of myeloid leukocyte differentiation)|go:""GO:0002768""(immune response-regulating cell surface receptor signaling pathway)|go:""GO:0002774""(Fc receptor mediated inhibitory signaling pathway)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0002902""(regulation of B cell apoptotic process)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005161""(platelet-derived growth factor receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006914""(autophagy)|go:""GO:0006974""(DNA damage response)|go:""GO:0006991""(response to sterol depletion)|go:""GO:0007165""(signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009725""(response to hormone)|go:""GO:0009743""(response to carbohydrate)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0015908""(fatty acid transport)|go:""GO:0016301""(kinase activity)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030222""(eosinophil differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0031175""(neuron projection development)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032868""(response to insulin)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034136""(negative regulation of toll-like receptor 2 signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0034144""(negative regulation of toll-like receptor 4 signaling pathway)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0038043""(interleukin-5-mediated signaling pathway)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0038159""(C-X-C chemokine receptor CXCR4 signaling pathway)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0043208""(glycosphingolipid binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043304""(regulation of mast cell degranulation)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048678""(response to axon injury)|go:""GO:0050777""(negative regulation of immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050855""(regulation of B cell receptor signaling pathway)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060369""(positive regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070447""(positive regulation of oligodendrocyte progenitor proliferation)|go:""GO:0070667""(negative regulation of mast cell proliferation)|go:""GO:0070668""(positive regulation of mast cell proliferation)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0090025""(regulation of monocyte chemotaxis)|go:""GO:0090330""(regulation of platelet aggregation)|go:""GO:0097028""(dendritic cell differentiation)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099091""(postsynaptic specialization, intracellular component)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0141038""(phosphatidylinositol 3-kinase activator activity)|go:""GO:0150076""(neuroinflammatory response)|go:""GO:1902532""(negative regulation of intracellular signal transduction)|go:""GO:1902961""(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:""GO:2000670""(positive regulation of dendritic cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035748|interpro:IPR035852|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P07948|rcsb pdb:1W1F|rcsb pdb:1WA7|rcsb pdb:3A4O|rcsb pdb:5XY1|rcsb pdb:6NMW|rcsb pdb:8WFF|reactome:R-HSA-114604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2454202|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5690714|reactome:R-HSA-69231|reactome:R-HSA-75892|reactome:R-HSA-9006335|reactome:R-HSA-9027276|reactome:R-HSA-9027277|reactome:R-HSA-9027283|reactome:R-HSA-9027284|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983695"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:SqXPSC+g2ZuGHy6TAPV4HcpXe6U9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9ULF5	intact:EBI-27055396	intact:EBI-2823223|uniprotkb:A8K5C6|uniprotkb:Q3MJA4|uniprotkb:Q6DKH6|uniprotkb:Q68CR5|uniprotkb:Q9Y3Z1|uniprotkb:B4DGU0|ensembl:ENSP00000352655.5|ensembl:ENSP00000386766.3	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:s39aa_human(display_long)|uniprotkb:SLC39A10(gene name)|psi-mi:SLC39A10(display_short)|uniprotkb:KIAA1265(gene name synonym)|uniprotkb:ZIP10(gene name synonym)|uniprotkb:Solute carrier family 39 member 10(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 10(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:XP_011509806.1|refseq:XP_011509807.1|refseq:XP_011509808.1|refseq:NP_001120729.1|refseq:NP_065075.1|refseq:XP_005246746.2|ensembl:ENSG00000196950.14(gene)|ensembl:ENST00000359634.10(transcript)|ensembl:ENST00000409086.7(transcript)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0002903""(negative regulation of B cell apoptotic process)|go:""GO:0005385""(zinc ion transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030003""(intracellular monoatomic cation homeostasis)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0050861""(positive regulation of B cell receptor signaling pathway)|go:""GO:0071577""(zinc ion transmembrane transport)|go:""GO:0071578""(zinc ion import across plasma membrane)|go:""GO:0140410""(""monoatomic cation:bicarbonate symporter activity"")|interpro:IPR003689(Zinc/iron permease)|interpro:IPR050799|mint:Q9ULF5|reactome:R-HSA-442380|panther:PTHR12191(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:j7A/tPe/lJCOscfBZhF1mSe99k09606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q07065	intact:EBI-27055396	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265.4|intact:EBI-21353377	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_006816.2|ensembl:ENSG00000136026.14(gene)|ensembl:ENST00000378026.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005811""(lipid droplet)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042599""(lamellar body)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270|panther:PTHR45161(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9H2H9	intact:EBI-27055396	intact:EBI-9978441|uniprotkb:Q8NC61|uniprotkb:Q8NCF8|uniprotkb:Q96JX2|uniprotkb:Q9H2Q2|ensembl:ENSP00000381634.4|ensembl:ENSP00000398142.1|ensembl:ENSP00000447853.1|ensembl:ENSP00000449607.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:s38a1_human(display_long)|uniprotkb:SLC38A1(gene name)|psi-mi:SLC38A1(display_short)|uniprotkb:ATA1(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:SAT1(gene name synonym)|uniprotkb:SNAT1(gene name synonym)|uniprotkb:Amino acid transporter A1(gene name synonym)|uniprotkb:N-system amino acid transporter 2(gene name synonym)|uniprotkb:Solute carrier family 38 member 1(gene name synonym)|uniprotkb:System A amino acid transporter 1(gene name synonym)|uniprotkb:System N amino acid transporter 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001070952.1|refseq:NP_001265316.1|refseq:NP_001265317.1|refseq:NP_001265318.1|refseq:NP_109599.3|ensembl:ENSG00000111371.16(gene)|ensembl:ENST00000398637.10(transcript)|ensembl:ENST00000439706.5(transcript)|ensembl:ENST00000546893.5(transcript)|ensembl:ENST00000549049.5(transcript)|go:""GO:0001504""(neurotransmitter uptake)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005283""(""amino acid:sodium symporter activity"")|go:""GO:0005295""(""neutral L-amino acid:sodium symporter activity"")|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0006865""(amino acid transport)|go:""GO:0006868""(glutamine transport)|go:""GO:0007565""(female pregnancy)|go:""GO:0009449""(gamma-aminobutyric acid biosynthetic process)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015186""(L-glutamine transmembrane transporter activity)|go:""GO:0015375""(""glycine:sodium symporter activity"")|go:""GO:0015655""(""alanine:sodium symporter activity"")|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0032228""(regulation of synaptic transmission, GABAergic)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043090""(amino acid import)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098591""(external side of apical plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901036""(positive regulation of L-glutamine import across plasma membrane)|go:""GO:1902475""(L-alpha-amino acid transmembrane transport)|interpro:IPR013057(Amino acid transporter, transmembrane)|mint:Q9H2H9|reactome:R-HSA-210455|reactome:R-HSA-352230|panther:PTHR22950(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:bywv401DbQBHRZvcPc8o8mp8nfE9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8N9N7	intact:EBI-27055396	intact:EBI-4290511|uniprotkb:Q7Z2Z6|uniprotkb:Q8N1T6|ensembl:ENSP00000326817.2|ensembl:ENSP00000380319.3|ensembl:ENSP00000455445.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:lrc57_human(display_long)|uniprotkb:LRRC57(gene name)|psi-mi:LRRC57(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_694992.2|ensembl:ENSG00000180979.10(gene)|ensembl:ENST00000323443.6(transcript)|ensembl:ENST00000397130.8(transcript)|ensembl:ENST00000563454.5(transcript)|go:""GO:0016020""(membrane)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050216|mint:Q8N9N7|panther:PTHR16083(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:0AwiIo1X4p5m32JCTCQswlwyH6k9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9P2D6	intact:EBI-27055396	intact:EBI-2685819|uniprotkb:Q5JXK0|uniprotkb:Q9H0F2|uniprotkb:Q68DW0|uniprotkb:Q6P081|uniprotkb:Q9NXL5|uniprotkb:Q9NU48|uniprotkb:A2RRQ5|uniprotkb:Q5JXK1|uniprotkb:Q9NUQ5|uniprotkb:Q3C0H3|ensembl:ENSP00000359510.4|ensembl:ENSP00000410768.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:f135a_human(display_long)|uniprotkb:KIAA1411(gene name synonym)|uniprotkb:FAM135A(gene name)|psi-mi:FAM135A(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	refseq:NP_001099001.1|refseq:NP_001156001.1|refseq:NP_065870.3|ensembl:ENSG00000082269.17(gene)|ensembl:ENST00000370479.7(transcript)|ensembl:ENST00000418814.7(transcript)|interpro:IPR007751(Protein of unknown function DUF676, hydrolase-like)|interpro:IPR022122|interpro:IPR029058|interpro:IPR044294|mint:Q9P2D6|reactome:R-HSA-9696273|refseq:NP_001317931.1|refseq:NP_001317926.1|refseq:NP_001317930.1|refseq:XP_016866614.1|refseq:XP_016866615.1|refseq:XP_016866616.1|panther:PTHR12482(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:eOitcL5fc1tMBNKlAubhp3KrrXY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9H3P7	intact:EBI-27055396	intact:EBI-1791792|ensembl:ENSP00000355777.5|uniprotkb:Q5VTJ0|uniprotkb:Q6P9F1|uniprotkb:Q8IZC5|uniprotkb:Q8N4D6|uniprotkb:Q9H6U3|uniprotkb:B2RB29	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:gcp60_human(display_long)|uniprotkb:GOCAP1(gene name synonym)|uniprotkb:GOLPH1(gene name synonym)|uniprotkb:ACBD3(gene name)|psi-mi:ACBD3(display_short)|uniprotkb:GCP60(gene name synonym)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000182827.9(gene)|ensembl:ENST00000366812.6(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006694""(steroid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR009038(GOLD)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|interpro:IPR036598|interpro:IPR052269|mint:Q9H3P7|rcsb pdb:2N72|rcsb pdb:2N73|rcsb pdb:5LZ1|rcsb pdb:5LZ3|rcsb pdb:5LZ6|rcsb pdb:5TDQ|rcsb pdb:6HLN|rcsb pdb:6HLT|rcsb pdb:6HLV|rcsb pdb:6HLW|rcsb pdb:6HM8|rcsb pdb:6HMV|reactome:R-HSA-432722|refseq:NP_073572.2|dip:DIP-40673N|panther:PTHR22973(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:jAaMXnoXG6RGj+lAgIYk1inXA6o9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q8TDN6	intact:EBI-27055396	intact:EBI-1052326|uniprotkb:Q3ZTT4|uniprotkb:Q8N453|uniprotkb:Q96DH1|uniprotkb:A8K0P5|ensembl:ENSP00000338862.5	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:brx1_human(display_long)|uniprotkb:BRIX1(gene name)|psi-mi:BRIX1(display_short)|uniprotkb:BXDC2(gene name synonym)|uniprotkb:BRIX(gene name synonym)|uniprotkb:Brix domain-containing protein 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_060791.3|ensembl:ENSG00000113460.13(gene)|ensembl:ENST00000336767.6(transcript)|go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0003723""(RNA binding)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0006364""(rRNA processing)|go:""GO:0019843""(rRNA binding)|interpro:IPR007109(Brix)|interpro:IPR026532|mint:Q8TDN6|rcsb pdb:8FKP|rcsb pdb:8FKQ|rcsb pdb:8FKR|rcsb pdb:8FKS|rcsb pdb:8FKT|rcsb pdb:8FKU|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|panther:PTHR13634(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:Xa2UDOXgdmWyJ7qBZsdInDt9Vaw9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9UHD1	intact:EBI-27055396	intact:EBI-2550959|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49|ensembl:ENSP00000319255.6|ensembl:ENSP00000496744.1	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001137545.1|refseq:NP_036256.2|ensembl:ENSG00000110172.12(gene)|ensembl:ENSG00000285023.2(gene)|ensembl:ENST00000320585.11(transcript)|ensembl:ENST00000646618.2(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0043531""(ADP binding)|go:""GO:0051298""(centrosome duplication)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:1900034""(regulation of cellular response to heat)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|mint:Q9UHD1|rcsb pdb:2YRT|panther:PTHR12621(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q9Y5Y0	intact:EBI-27055396	intact:EBI-9681535|ensembl:ENSP00000355938.4|uniprotkb:Q1HE16|uniprotkb:Q86XY9|uniprotkb:Q9NVR9	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:flvc1_human(display_long)|uniprotkb:Feline leukemia virus subgroup C receptor-related protein 1(gene name synonym)|uniprotkb:FLVCR1(gene name)|psi-mi:FLVCR1(display_short)|uniprotkb:FLVCR(gene name synonym)|uniprotkb:Heme transporter FLVCR1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"ensembl:ENSG00000162769.13(gene)|ensembl:ENST00000366971.9(transcript)|go:""GO:0001568""(blood vessel development)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0006839""(mitochondrial transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0008654""(phospholipid biosynthetic process)|go:""GO:0015220""(choline transmembrane transporter activity)|go:""GO:0015232""(heme transmembrane transporter activity)|go:""GO:0015871""(choline transport)|go:""GO:0015886""(heme transport)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0034228""(ethanolamine transmembrane transporter activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0043249""(erythrocyte maturation)|go:""GO:0046620""(regulation of organ growth)|go:""GO:0048536""(spleen development)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0060323""(head morphogenesis)|go:""GO:0097037""(heme export)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|interpro:IPR049680|mint:Q9Y5Y0|rcsb pdb:8QCS|rcsb pdb:8QCT|rcsb pdb:8R8T|rcsb pdb:8UBW|rcsb pdb:8UBX|rcsb pdb:8UBY|rcsb pdb:8UBZ|rcsb pdb:8UC0|reactome:R-HSA-189451|reactome:R-HSA-917937|refseq:NP_054772.1|panther:PTHR10924(orthology-group)|efo:""Orphanet:88628"""	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:bb6L2akAjb64NgdW94M2I3uMhxQ9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:P52569	intact:EBI-27055396	intact:EBI-2858278|uniprotkb:O15291|uniprotkb:Q6NSZ7|uniprotkb:O15292|uniprotkb:Q14CQ6|uniprotkb:B7ZL54|uniprotkb:Q86TC6|ensembl:ENSP00000419140.2|ensembl:ENSP00000430464.1|ensembl:ENSP00000492016.2	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:ctr2_human(display_long)|uniprotkb:SLC7A2(gene name)|psi-mi:SLC7A2(display_short)|uniprotkb:ATRC2(gene name synonym)|uniprotkb:CAT2(gene name synonym)|uniprotkb:Solute carrier family 7 member 2(gene name synonym)|uniprotkb:Low affinity cationic amino acid transporter 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_001008539.3|refseq:NP_001158243.1|refseq:NP_003037.4|refseq:XP_005273667.1|refseq:XP_005273668.1|refseq:XP_005273669.1|ensembl:ENSG00000003989.18(gene)|ensembl:ENST00000494857.6(transcript)|ensembl:ENST00000522656.5(transcript)|ensembl:ENST00000640220.1(transcript)|go:""GO:0000064""(L-ornithine transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015174""(basic amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015189""(L-lysine transmembrane transporter activity)|go:""GO:0015807""(L-amino acid transport)|go:""GO:0030054""(cell junction)|go:""GO:0061459""(L-arginine transmembrane transporter activity)|go:""GO:0089718""(amino acid import across plasma membrane)|go:""GO:0097638""(L-arginine import across plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902475""(L-alpha-amino acid transmembrane transport)|go:""GO:1903352""(L-ornithine transmembrane transport)|go:""GO:1903826""(L-arginine transmembrane transport)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004755(Cationic amino acid transport permease)|interpro:IPR029485|mint:P52569|reactome:R-HSA-352230|refseq:XP_016869235.1|refseq:XP_016869236.1|panther:PTHR43243(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:sTEceBwq7KUpaNgBKVX2+ss/oKU9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NFP4	uniprotkb:Q92609	intact:EBI-27055396	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|uniprotkb:C9JP52|ensembl:ENSP00000253692.6|ensembl:ENSP00000398127.4	psi-mi:a0a0h3nfp4_salts(display_long)|uniprotkb:G1X13_21010(orf name)|uniprotkb:G1X17_21810(orf name)|uniprotkb:G1X23_21380(orf name)|uniprotkb:G1X29_21185(orf name)|uniprotkb:G1X32_21435(orf name)|uniprotkb:G1X38_21730(orf name)|uniprotkb:G1X42_14115(orf name)|uniprotkb:G1X47_21160(orf name)|uniprotkb:G1X49_21660(orf name)|uniprotkb:G1X51_20890(orf name)|uniprotkb:G1X52_21170(orf name)|uniprotkb:G1X66_20845(orf name)|uniprotkb:G1X68_22695(orf name)|uniprotkb:G1X69_21750(orf name)|uniprotkb:G1X71_21485(orf name)|uniprotkb:G1X76_21135(orf name)|uniprotkb:G1X80_21270(orf name)|uniprotkb:SL1344_1161(locus name)|uniprotkb:G1X84_21180(orf name)|uniprotkb:G1X85_20705(orf name)|uniprotkb:G1X86_21475(orf name)|uniprotkb:G1X94_20995(orf name)|uniprotkb:G1X96_21480(orf name)|uniprotkb:G1X99_21695(orf name)|uniprotkb:G1Y02_21175(orf name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:G1W50_21000(orf name)|uniprotkb:G1W53_20875(orf name)|uniprotkb:G1W54_21465(orf name)|uniprotkb:G1W56_24125(orf name)|uniprotkb:G1W63_20545(orf name)|uniprotkb:G1W64_21175(orf name)|uniprotkb:G1W86_21290(orf name)|uniprotkb:G1W87_19730(orf name)|uniprotkb:G1W89_20040(orf name)|uniprotkb:G1W92_14115(orf name)|uniprotkb:G1X03_21510(orf name)|uniprotkb:G1X04_03720(orf name)|uniprotkb:G1X09_21020(orf name)|uniprotkb:G1X10_21400(orf name)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055788|imex:IM-29147-27	intact-miscore:0.47	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR044928|mint:A0A0H3NFP4|refseq:WP_001520468.1|interpro:IPR010637(Sif)	"refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1|ensembl:ENSG00000131374.15(gene)|ensembl:ENST00000253692.11(transcript)|ensembl:ENST00000429383.8(transcript)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005776""(autophagosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0035612""(AP-2 adaptor complex binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042594""(response to starvation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:1905394""(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|panther:PTHR22957(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/26	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk216597	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:1E880C0156645844|rigid:erCdf40oZ0wMLMNEiqphvmgHmco	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9UHD1	intact:EBI-10726177	intact:EBI-2550959|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49|ensembl:ENSP00000319255.6|ensembl:ENSP00000496744.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001137545.1|refseq:NP_036256.2|ensembl:ENSG00000110172.12(gene)|ensembl:ENSG00000285023.2(gene)|ensembl:ENST00000320585.11(transcript)|ensembl:ENST00000646618.2(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0043531""(ADP binding)|go:""GO:0051298""(centrosome duplication)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:1900034""(regulation of cellular response to heat)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|mint:Q9UHD1|rcsb pdb:2YRT|panther:PTHR12621(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9Y5Y0	intact:EBI-10726177	intact:EBI-9681535|ensembl:ENSP00000355938.4|uniprotkb:Q1HE16|uniprotkb:Q86XY9|uniprotkb:Q9NVR9	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:flvc1_human(display_long)|uniprotkb:Feline leukemia virus subgroup C receptor-related protein 1(gene name synonym)|uniprotkb:FLVCR1(gene name)|psi-mi:FLVCR1(display_short)|uniprotkb:FLVCR(gene name synonym)|uniprotkb:Heme transporter FLVCR1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000162769.13(gene)|ensembl:ENST00000366971.9(transcript)|go:""GO:0001568""(blood vessel development)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0006839""(mitochondrial transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0008654""(phospholipid biosynthetic process)|go:""GO:0015220""(choline transmembrane transporter activity)|go:""GO:0015232""(heme transmembrane transporter activity)|go:""GO:0015871""(choline transport)|go:""GO:0015886""(heme transport)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0034228""(ethanolamine transmembrane transporter activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0043249""(erythrocyte maturation)|go:""GO:0046620""(regulation of organ growth)|go:""GO:0048536""(spleen development)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0060323""(head morphogenesis)|go:""GO:0097037""(heme export)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|interpro:IPR049680|mint:Q9Y5Y0|rcsb pdb:8QCS|rcsb pdb:8QCT|rcsb pdb:8R8T|rcsb pdb:8UBW|rcsb pdb:8UBX|rcsb pdb:8UBY|rcsb pdb:8UBZ|rcsb pdb:8UC0|reactome:R-HSA-189451|reactome:R-HSA-917937|refseq:NP_054772.1|panther:PTHR10924(orthology-group)|efo:""Orphanet:88628"""	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:bb6L2akAjb64NgdW94M2I3uMhxQ9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P52569	intact:EBI-10726177	intact:EBI-2858278|uniprotkb:O15291|uniprotkb:Q6NSZ7|uniprotkb:O15292|uniprotkb:Q14CQ6|uniprotkb:B7ZL54|uniprotkb:Q86TC6|ensembl:ENSP00000419140.2|ensembl:ENSP00000430464.1|ensembl:ENSP00000492016.2	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:ctr2_human(display_long)|uniprotkb:SLC7A2(gene name)|psi-mi:SLC7A2(display_short)|uniprotkb:ATRC2(gene name synonym)|uniprotkb:CAT2(gene name synonym)|uniprotkb:Solute carrier family 7 member 2(gene name synonym)|uniprotkb:Low affinity cationic amino acid transporter 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001008539.3|refseq:NP_001158243.1|refseq:NP_003037.4|refseq:XP_005273667.1|refseq:XP_005273668.1|refseq:XP_005273669.1|ensembl:ENSG00000003989.18(gene)|ensembl:ENST00000494857.6(transcript)|ensembl:ENST00000522656.5(transcript)|ensembl:ENST00000640220.1(transcript)|go:""GO:0000064""(L-ornithine transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015174""(basic amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015189""(L-lysine transmembrane transporter activity)|go:""GO:0015807""(L-amino acid transport)|go:""GO:0030054""(cell junction)|go:""GO:0061459""(L-arginine transmembrane transporter activity)|go:""GO:0089718""(amino acid import across plasma membrane)|go:""GO:0097638""(L-arginine import across plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902475""(L-alpha-amino acid transmembrane transport)|go:""GO:1903352""(L-ornithine transmembrane transport)|go:""GO:1903826""(L-arginine transmembrane transport)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004755(Cationic amino acid transport permease)|interpro:IPR029485|mint:P52569|reactome:R-HSA-352230|refseq:XP_016869235.1|refseq:XP_016869236.1|panther:PTHR43243(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:sTEceBwq7KUpaNgBKVX2+ss/oKU9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q8TDN6	intact:EBI-10726177	intact:EBI-1052326|uniprotkb:Q3ZTT4|uniprotkb:Q8N453|uniprotkb:Q96DH1|uniprotkb:A8K0P5|ensembl:ENSP00000338862.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:brx1_human(display_long)|uniprotkb:BRIX1(gene name)|psi-mi:BRIX1(display_short)|uniprotkb:BXDC2(gene name synonym)|uniprotkb:BRIX(gene name synonym)|uniprotkb:Brix domain-containing protein 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_060791.3|ensembl:ENSG00000113460.13(gene)|ensembl:ENST00000336767.6(transcript)|go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0003723""(RNA binding)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0006364""(rRNA processing)|go:""GO:0019843""(rRNA binding)|interpro:IPR007109(Brix)|interpro:IPR026532|mint:Q8TDN6|rcsb pdb:8FKP|rcsb pdb:8FKQ|rcsb pdb:8FKR|rcsb pdb:8FKS|rcsb pdb:8FKT|rcsb pdb:8FKU|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|panther:PTHR13634(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:Xa2UDOXgdmWyJ7qBZsdInDt9Vaw9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q92609	intact:EBI-10726177	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|uniprotkb:C9JP52|ensembl:ENSP00000253692.6|ensembl:ENSP00000398127.4	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1|ensembl:ENSG00000131374.15(gene)|ensembl:ENST00000253692.11(transcript)|ensembl:ENST00000429383.8(transcript)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005776""(autophagosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0035612""(AP-2 adaptor complex binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042594""(response to starvation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:1905394""(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|panther:PTHR22957(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P0CG47	intact:EBI-10726177	intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697.3|ensembl:ENSP00000379178.1|ensembl:ENSP00000379180.1|ensembl:ENSP00000478771.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:101023""|efo:""Orphanet:155878""|efo:""Orphanet:99771""|efo:""Orphanet:99772""|ensembl:ENSG00000170315.14(gene)|ensembl:ENST00000302182.8(transcript)|ensembl:ENST00000395837.1(transcript)|ensembl:ENST00000395839.5(transcript)|ensembl:ENST00000614404.1(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007141""(male meiosis I)|go:""GO:0007144""(female meiosis I)|go:""GO:0008585""(female gonad development)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019941""(modification-dependent protein catabolic process)|go:""GO:0021888""(hypothalamus gonadotrophin-releasing hormone neuron development)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031386""(protein tag activity)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043523""(regulation of neuron apoptotic process)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0060613""(fat pad development)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:0097009""(energy homeostasis)|go:""GO:1902255""(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:1902527""(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR050158|mint:P0CG47|rcsb pdb:2KHW|rcsb pdb:2MBB|rcsb pdb:2MRO|rcsb pdb:2MSG|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:6XQC|rcsb pdb:6XZ1|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7BU0|rcsb pdb:7CAP|rcsb pdb:7DNI|rcsb pdb:7DNJ|rcsb pdb:7E8I|rcsb pdb:7F7X|rcsb pdb:7JMS|rcsb pdb:7LYC|rcsb pdb:7M2K|rcsb pdb:7MC9|rcsb pdb:7MEY|rcsb pdb:7MYF|rcsb pdb:7MYH|rcsb pdb:7NBB|rcsb pdb:7NPO|rcsb pdb:7OJE|rcsb pdb:7OJX|rcsb pdb:7QO4|rcsb pdb:7QO5|rcsb pdb:7RBR|rcsb pdb:7RMA|rcsb pdb:7UD5|rcsb pdb:7US1|rcsb pdb:7UV5|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:7W3U|rcsb pdb:7W54|rcsb pdb:7XCR|rcsb pdb:7XCT|rcsb pdb:7YQK|rcsb pdb:8A67|rcsb pdb:8BS9|rcsb pdb:8C07|rcsb pdb:8C61|rcsb pdb:8CMR|rcsb pdb:8DMQ|rcsb pdb:8DMS|rcsb pdb:8DU4|rcsb pdb:8EFW|rcsb pdb:8EFX|rcsb pdb:8EHO|rcsb pdb:8G6G|rcsb pdb:8G6H|rcsb pdb:8G6Q|rcsb pdb:8G6S|rcsb pdb:8GRM|rcsb pdb:8H1T|rcsb pdb:8HQY|rcsb pdb:8IC9|rcsb pdb:8ITP|rcsb pdb:8J1P|rcsb pdb:8OYP|rcsb pdb:8Q00|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8TXV|rcsb pdb:8TXW|rcsb pdb:8TXX|rcsb pdb:8V25|rcsb pdb:8V26|rcsb pdb:8V27|rcsb pdb:8V28|rcsb pdb:8W31|rcsb pdb:8WG5|rcsb pdb:8XEP|rcsb pdb:9AVT|rcsb pdb:9AVW|rcsb pdb:9AZJ|rcsb pdb:9B0Z|rcsb pdb:9B12|rcsb pdb:9C5E|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866427|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-909733|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9680350|reactome:R-HSA-9683683|reactome:R-HSA-9692916|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-9725370|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-9755511|reactome:R-HSA-9758274|reactome:R-HSA-9762114|reactome:R-HSA-977225|reactome:R-HSA-9824878|reactome:R-HSA-9828211|reactome:R-HSA-983168|reactome:R-HSA-9833109|reactome:R-HSA-9861718|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|refseq:NP_061828.1|panther:PTHR10666(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q92841	intact:EBI-10726177	intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536.2	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_006377.2|dip:DIP-29843N|ensembl:ENSG00000100201.23(gene)|ensembl:ENST00000403230.3(transcript)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0002376""(immune system process)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006364""(rRNA processing)|go:""GO:0006396""(RNA processing)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0010586""(miRNA metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051607""(defense response to virus)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2001014""(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR046330|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|panther:PTHR47958(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q07065	intact:EBI-10726177	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265.4|intact:EBI-21353377	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_006816.2|ensembl:ENSG00000136026.14(gene)|ensembl:ENST00000378026.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005811""(lipid droplet)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042599""(lamellar body)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270|panther:PTHR45161(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9P035	intact:EBI-10726177	intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|ensembl:ENSP00000261875.5|uniprotkb:B4DRF4|intact:EBI-28973764	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_057479.2|ensembl:ENSG00000074696.13(gene)|ensembl:ENST00000261875.10(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0018812""(3-hydroxyacyl-CoA dehydratase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030148""(sphingolipid biosynthetic process)|go:""GO:0030497""(fatty acid elongation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042761""(very long-chain fatty acid biosynthetic process)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0046726""(positive regulation by virus of viral protein levels in host cell)|go:""GO:0102158""(""very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"")|go:""GO:1902532""(negative regulation of intracellular signal transduction)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876|panther:PTHR11035(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P07910	intact:EBI-10726177	intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|ensembl:ENSP00000404848.2|ensembl:ENSP00000451291.1|ensembl:ENSP00000452276.1|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000092199.19(gene)|ensembl:ENST00000420743.6(transcript)|ensembl:ENST00000554455.5(transcript)|ensembl:ENST00000557201.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000785""(chromatin)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005697""(telomerase holoenzyme complex)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008380""(RNA splicing)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0070034""(telomerase RNA binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1990247""(N6-methyladenosine-containing RNA reader activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|interpro:IPR051186|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|refseq:XP_006720188.1|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|efo:""Orphanet:528084""|dip:DIP-29854N|panther:PTHR13968(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P54886	intact:EBI-10726177	intact:EBI-1210304|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44|ensembl:ENSP00000360268.2	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000059573.9(gene)|ensembl:ENST00000371224.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004349""(glutamate 5-kinase activity)|go:""GO:0004350""(glutamate-5-semialdehyde dehydrogenase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006536""(glutamate metabolic process)|go:""GO:0006561""(proline biosynthetic process)|go:""GO:0006592""(ornithine biosynthetic process)|go:""GO:0009266""(response to temperature stimulus)|go:""GO:0019240""(citrulline biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539|reactome:R-HSA-9837999|refseq:NP_001017423.1|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|refseq:NP_002851.2|efo:""Orphanet:35664""|efo:""Orphanet:447753""|efo:""Orphanet:447757""|efo:""Orphanet:447760""|efo:""Orphanet:90348""|panther:PTHR11063(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9P258	intact:EBI-10726177	intact:EBI-352547|uniprotkb:Q8IVL9|uniprotkb:Q9BSN6|uniprotkb:Q9NPV8|ensembl:ENSP00000364582.3|ensembl:ENSP00000364585.4|ensembl:ENSP00000486099.1|ensembl:ENSP00000486447.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:rcc2_human(display_long)|uniprotkb:RCC2(gene name)|psi-mi:RCC2(display_short)|uniprotkb:KIAA1470(gene name synonym)|uniprotkb:TD60(gene name synonym)|uniprotkb:Telophase disk protein of 60 kDa(gene name synonym)|uniprotkb:RCC1-like protein TD-60(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001129676.1|refseq:NP_061185.1|ensembl:ENSG00000179051.14(gene)|ensembl:ENSG00000281540.3(gene)|ensembl:ENST00000375433.3(transcript)|ensembl:ENST00000375436.9(transcript)|ensembl:ENST00000628984.1(transcript)|ensembl:ENST00000631021.3(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008017""(microtubule binding)|go:""GO:0010762""(regulation of fibroblast migration)|go:""GO:0010971""(positive regulation of G2/M transition of mitotic cell cycle)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034260""(negative regulation of GTPase activity)|go:""GO:0034506""(chromosome, centromeric core domain)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0051301""(cell division)|go:""GO:0051895""(negative regulation of focal adhesion assembly)|go:""GO:0051987""(positive regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0072356""(chromosome passenger complex localization to kinetochore)|go:""GO:1900025""(negative regulation of substrate adhesion-dependent cell spreading)|go:""GO:1900027""(regulation of ruffle assembly)|go:""GO:1990023""(mitotic spindle midzone)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR028641|mint:Q9P258|rcsb pdb:5GWN|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|panther:PTHR46207(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:z9+0avftBLs4Q3ODFHLEmJtd57A9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q86UE4	intact:EBI-10726177	intact:EBI-1046588|uniprotkb:Q8TCX3|uniprotkb:Q6PK07|ensembl:ENSP00000338235.3|uniprotkb:Q05DH2|uniprotkb:Q52QU9	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:lyric_human(display_long)|uniprotkb:Lysine-rich CEACAM1 co-isolated protein(gene name synonym)|uniprotkb:3D3/LYRIC(gene name synonym)|uniprotkb:Metastasis adhesion protein(gene name synonym)|uniprotkb:Astrocyte elevated gene-1 protein(gene name synonym)|uniprotkb:MTDH(gene name)|psi-mi:MTDH(display_short)|uniprotkb:AEG1(gene name synonym)|uniprotkb:LYRIC(gene name synonym)|uniprotkb:Metadherin(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000147649.10(gene)|ensembl:ENST00000336273.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046581""(intercellular canaliculus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR031402|interpro:IPR052305|mint:Q86UE4|rcsb pdb:4QMG|refseq:NP_848927.2|panther:PTHR23251(orthology-group)|ensembl:ENSP00000338235.3"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:daZhKhAOeoKGjfl0IXt1fZXn/I09606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q96PK6	intact:EBI-10726177	intact:EBI-954272|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484|ensembl:ENSP00000311747.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001185765.1|refseq:NP_006319.1|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|ensembl:ENSG00000239306.5(gene)|ensembl:ENST00000310137.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0007369""(gastrulation)|go:""GO:0009725""(response to hormone)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0045087""(innate immune response)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046600""(negative regulation of centriole replication)|go:""GO:0098534""(centriole assembly)|go:""GO:1902151""(regulation of response to DNA integrity checkpoint signaling)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:1990935""(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|interpro:IPR035979|interpro:IPR050907|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|panther:PTHR23147(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P04080	intact:EBI-10726177	intact:EBI-1051966|ensembl:ENSP00000291568.6	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:cytb_human(display_long)|uniprotkb:Stefin-B(gene name synonym)|uniprotkb:Liver thiol proteinase inhibitor(gene name synonym)|uniprotkb:CPI-B(gene name synonym)|uniprotkb:CSTB(gene name)|psi-mi:CSTB(display_short)|uniprotkb:CST6(gene name synonym)|uniprotkb:STFB(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000160213.10(gene)|ensembl:ENST00000291568.7(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0010466""(negative regulation of peptidase activity)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|interpro:IPR018073|interpro:IPR046350|mint:P04080|rcsb pdb:1STF|rcsb pdb:2OCT|rcsb pdb:4N6V|reactome:R-HSA-6798695|refseq:NP_000091.1|efo:""Orphanet:248""|efo:""Orphanet:308""|panther:PTHR11414(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:KwR0XgOq6SeHdqxriNE8xIUMmUo9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P23528	intact:EBI-10726177	intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629.5|ensembl:ENSP00000432660.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_005498.1|ensembl:ENSG00000172757.13(gene)|ensembl:ENST00000308162.10(transcript)|ensembl:ENST00000525451.6(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0009615""(response to virus)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030043""(actin filament fragmentation)|go:""GO:0030426""(growth cone)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032587""(ruffle membrane)|go:""GO:0040019""(positive regulation of embryonic development)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0051293""(establishment of spindle localization)|go:""GO:0061001""(regulation of dendritic spine morphogenesis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|dip:DIP-33000N|panther:PTHR11913(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P30048	intact:EBI-10726177	intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|ensembl:ENSP00000298510.2|uniprotkb:E9PH29	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_006784.1|ensembl:ENSG00000165672.7(gene)|ensembl:ENST00000298510.4(transcript)|go:""GO:0001893""(maternal placenta development)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0018171""(peptidyl-cysteine oxidation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033673""(negative regulation of kinase activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0102039""(NADH-dependent peroxiredoxin activity)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|interpro:IPR050217|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|refseq:NP_001289201.1|dip:DIP-33600N|panther:PTHR10681(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:+J/zV8u0jGCSzTGXafxgecTv/149606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9Y277	intact:EBI-10726177	intact:EBI-354196|uniprotkb:Q9UIS0|ensembl:ENSP00000022615.4	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:vdac3_human(display_long)|uniprotkb:VDAC3(gene name)|psi-mi:VDAC3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001129166.1|refseq:NP_005653.3|ensembl:ENSG00000078668.14(gene)|ensembl:ENST00000022615.9(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0001662""(behavioral fear response)|go:""GO:0005244""(voltage-gated monoatomic ion channel activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0007270""(neuron-neuron synaptic transmission)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007612""(learning)|go:""GO:0008308""(voltage-gated monoatomic anion channel activity)|go:""GO:0015288""(porin activity)|go:""GO:0015853""(adenine transport)|go:""GO:0016020""(membrane)|go:""GO:0045202""(synapse)|go:""GO:0046930""(pore complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120317""(sperm mitochondrial sheath assembly)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|mint:Q9Y277|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-8949215|panther:PTHR11743(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:En6g89Dp+C4s1ArGYJyVfUBVsO09606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9BSJ8	intact:EBI-10726177	intact:EBI-355956|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548|ensembl:ENSP00000377612.5|intact:EBI-21360363	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001171725.1|refseq:NP_056107.1|ensembl:ENSG00000139641.13(gene)|ensembl:ENST00000394048.10(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0008429""(phosphatidylethanolamine binding)|go:""GO:0016020""(membrane)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:0120014""(phospholipid transfer activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|interpro:IPR051634|mint:Q9BSJ8|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9845576|dip:DIP-57197N|panther:PTHR45761(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P10599	intact:EBI-10726177	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|ensembl:ENSP00000363641.5|uniprotkb:Q9UDG5|intact:EBI-1042712	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000136810.13(gene)|ensembl:ENST00000374517.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003723""(RNA binding)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0009314""(response to radiation)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0046826""(negative regulation of protein export from nucleus)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071731""(response to nitric oxide)|go:""GO:2000170""(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9818027|refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|panther:PTHR10438(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P00390	intact:EBI-10726177	intact:EBI-720325|uniprotkb:C8KIM0|uniprotkb:C8KIL8|uniprotkb:C8KIL9|uniprotkb:Q7Z5C9|uniprotkb:Q9NP63|uniprotkb:D3DSV3|ensembl:ENSP00000221130.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:gshr_human(display_long)|uniprotkb:GLUR(gene name synonym)|uniprotkb:GRD1(gene name synonym)|uniprotkb:GSR(gene name)|psi-mi:GSR(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:90030""|ensembl:ENSG00000104687.14(gene)|ensembl:ENST00000221130.11(transcript)|go:""GO:0004362""(""glutathione-disulfide reductase (NADPH) activity"")|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0009055""(electron transfer activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0050661""(NADP binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006322(Glutathione reductase, animal and bacterial)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|interpro:IPR046952|mint:P00390|rcsb pdb:1ALG|rcsb pdb:1BWC|rcsb pdb:1DNC|rcsb pdb:1GRA|rcsb pdb:1GRB|rcsb pdb:1GRE|rcsb pdb:1GRF|rcsb pdb:1GRG|rcsb pdb:1GRH|rcsb pdb:1GRT|rcsb pdb:1GSN|rcsb pdb:1K4Q|rcsb pdb:1XAN|rcsb pdb:2AAQ|rcsb pdb:2GH5|rcsb pdb:2GRT|rcsb pdb:3DJG|rcsb pdb:3DJJ|rcsb pdb:3DK4|rcsb pdb:3DK8|rcsb pdb:3DK9|rcsb pdb:3GRS|rcsb pdb:3GRT|rcsb pdb:3SQP|rcsb pdb:4GR1|rcsb pdb:4GRT|rcsb pdb:5GRT|reactome:R-HSA-2408550|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-9818027|refseq:NP_000628.2|refseq:NP_001182031.1|refseq:NP_001182032.1|refseq:NP_001182033.1|panther:PTHR42737(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:7vVXBCpDFlu835Jcm+ZeGReIA+Q9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P50402	intact:EBI-10726177	intact:EBI-489887|ensembl:ENSP00000358857.4|ensembl:ENSP00000507533.1|uniprotkb:Q6FI02	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000102119.12(gene)|ensembl:ENST00000369842.9(transcript)|ensembl:ENST00000683627.1(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006936""(muscle contraction)|go:""GO:0007517""(muscle organ development)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071763""(nuclear membrane organization)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0160045""(TMEM240-body)|go:""GO:1990000""(amyloid fibril formation)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|refseq:NP_000108.1|efo:""Orphanet:98863""|dip:DIP-34638N|panther:PTHR15171(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P36542	intact:EBI-10726177	intact:EBI-711768|ensembl:ENSP00000349142.7|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000165629.20(gene)|ensembl:ENST00000356708.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016020""(membrane)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|rcsb pdb:8H9E|rcsb pdb:8H9F|rcsb pdb:8H9I|rcsb pdb:8H9J|rcsb pdb:8H9L|rcsb pdb:8H9M|rcsb pdb:8H9P|rcsb pdb:8H9Q|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|reactome:R-HSA-9837999|refseq:NP_001001973.1|refseq:NP_005165.1|panther:PTHR11693(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q07666	intact:EBI-10726177	intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829.7	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|panther:PTHR11208(orthology-group)|ensembl:ENSG00000121774.18(gene)|ensembl:ENST00000327300.12(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0016020""(membrane)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046831""(regulation of RNA export from nucleus)|go:""GO:0046833""(positive regulation of RNA export from nucleus)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070618""(Grb2-Sos complex)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|interpro:IPR045071|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|rcsb pdb:7Z89|rcsb pdb:7Z8A|rcsb pdb:7Z9A|rcsb pdb:7Z9B|rcsb pdb:7ZAB|rcsb pdb:7ZAC|rcsb pdb:7ZAF|rcsb pdb:7ZAM|reactome:R-HSA-8849468"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9UEY8	intact:EBI-10726177	intact:EBI-2838698|uniprotkb:Q9UEY7|uniprotkb:O43243|uniprotkb:Q92773|uniprotkb:Q5VU09|uniprotkb:D3DRA8|ensembl:ENSP00000348381.4|intact:EBI-28975834	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:addg_human(display_long)|uniprotkb:ADD3(gene name)|psi-mi:ADD3(display_short)|uniprotkb:ADDL(gene name synonym)|uniprotkb:Adducin-like protein 70(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000148700.15(gene)|ensembl:ENST00000356080.9(transcript)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005938""(cell cortex)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051495""(positive regulation of cytoskeleton organization)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|interpro:IPR051017|mint:Q9UEY8|reactome:R-HSA-5223345|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_001112.2|refseq:NP_001307520.1|refseq:NP_001307521.1|refseq:NP_001307522.1|refseq:NP_001307523.1|refseq:NP_058432.1|refseq:NP_063968.1|efo:""Orphanet:210141""|panther:PTHR10672(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:10ZAHAI90VaVf/xUxFcNVX5cIts9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P20700	intact:EBI-10726177	intact:EBI-968218|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6|ensembl:ENSP00000261366.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:2514""|efo:""Orphanet:99027""|dip:DIP-34897N|ensembl:ENSG00000113368.12(gene)|ensembl:ENST00000261366.10(transcript)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043274""(phospholipase binding)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|rcsb pdb:3UMN|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:5BNW|rcsb pdb:5VVX|rcsb pdb:7DTG|reactome:R-HSA-1221632|reactome:R-HSA-2559584|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|panther:PTHR45721(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P27824	intact:EBI-10726177	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000247461.4|ensembl:ENSP00000391646.2|ensembl:ENSP00000421434.2|ensembl:ENSP00000421813.2|ensembl:ENSP00000424063.1|ensembl:ENSP00000424745.2|ensembl:ENSP00000491760.1|ensembl:ENSP00000492372.1|ensembl:ENSP00000492868.1|ensembl:ENSP00000505013.1|ensembl:ENSP00000505202.1|ensembl:ENSP00000505526.1|ensembl:ENSP00000505960.1|ensembl:ENSP00000506003.1|ensembl:ENSP00000506021.1|ensembl:ENSP00000506061.1|ensembl:ENSP00000506078.1|ensembl:ENSP00000506509.1|ensembl:ENSP00000506568.1|ensembl:ENSP00000506583.1|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|ensembl:ENSG00000127022.16(gene)|ensembl:ENSG00000283777.2(gene)|ensembl:ENST00000247461.9(transcript)|ensembl:ENST00000452673.6(transcript)|ensembl:ENST00000502296.6(transcript)|ensembl:ENST00000504734.5(transcript)|ensembl:ENST00000509563.2(transcript)|ensembl:ENST00000513246.6(transcript)|ensembl:ENST00000638425.1(transcript)|ensembl:ENST00000638706.2(transcript)|ensembl:ENST00000639938.1(transcript)|ensembl:ENST00000680013.1(transcript)|ensembl:ENST00000680042.1(transcript)|ensembl:ENST00000680092.1(transcript)|ensembl:ENST00000680618.1(transcript)|ensembl:ENST00000681072.1(transcript)|ensembl:ENST00000681168.1(transcript)|ensembl:ENST00000681476.1(transcript)|ensembl:ENST00000681674.1(transcript)|ensembl:ENST00000681712.1(transcript)|ensembl:ENST00000681733.1(transcript)|ensembl:ENST00000681903.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006457""(protein folding)|go:""GO:0009306""(protein secretion)|go:""GO:0016020""(membrane)|go:""GO:0019082""(viral protein processing)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0036503""(ERAD pathway)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0044322""(endoplasmic reticulum quality control compartment)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098793""(presynapse)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|dip:DIP-457N|panther:PTHR11073(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9Y6M7	intact:EBI-10726177	intact:EBI-1044546|uniprotkb:O60350|uniprotkb:Q6AHZ9|uniprotkb:Q9HC88|uniprotkb:Q9UIB9|uniprotkb:A6NIA8|uniprotkb:B2CI53|uniprotkb:B5M451|uniprotkb:B5M452|uniprotkb:B5M453|uniprotkb:B6DY52|uniprotkb:B6DY53|uniprotkb:C9JST9|uniprotkb:B5M449|uniprotkb:D3K174|uniprotkb:D3K175|intact:EBI-10982200|intact:EBI-11577841|ensembl:ENSP00000295736.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	"psi-mi:s4a7_human(display_long)|uniprotkb:Sodium bicarbonate cotransporter 2(gene name synonym)|uniprotkb:Sodium bicarbonate cotransporter 2b(gene name synonym)|uniprotkb:Solute carrier family 4 member 7(gene name synonym)|uniprotkb:SLC4A7(gene name)|psi-mi:SLC4A7(display_short)|uniprotkb:BT(gene name synonym)|uniprotkb:NBC2(gene name synonym)|uniprotkb:NBC2B(gene name synonym)|uniprotkb:NBC3(gene name synonym)|uniprotkb:SBC2(gene name synonym)|uniprotkb:SLC4A6(gene name synonym)|uniprotkb:NBCn1(gene name synonym)|uniprotkb:""Electroneutral Na/HCO(3) cotransporter""(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_003606.3|refseq:NP_001245308.1|refseq:NP_001245309.1|refseq:NP_001308032.1|refseq:NP_001308033.1|refseq:NP_001308034.1|refseq:NP_001308035.1|refseq:NP_001308036.1|refseq:NP_001308037.1|refseq:XP_016863017.1|refseq:XP_016863018.1|ensembl:ENSG00000033867.18(gene)|ensembl:ENST00000295736.9(transcript)|go:""GO:0005452""(""solute:inorganic anion antiporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006221""(pyrimidine nucleotide biosynthetic process)|go:""GO:0008509""(monoatomic anion transmembrane transporter activity)|go:""GO:0008510""(""sodium:bicarbonate symporter activity"")|go:""GO:0015701""(bicarbonate transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0032420""(stereocilium)|go:""GO:0051453""(regulation of intracellular pH)|go:""GO:0055085""(transmembrane transport)|go:""GO:0060117""(auditory receptor cell development)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0090383""(phagosome acidification)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|mint:Q9Y6M7|reactome:R-HSA-425381|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9035034|panther:PTHR11453(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:vsq90qG3qxPyZgkoyvS0MPamvOg9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:O15173	intact:EBI-10726177	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425.4|ensembl:ENSP00000429301.2	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_006311.2|ensembl:ENSG00000164040.18(gene)|ensembl:ENST00000296425.10(transcript)|ensembl:ENST00000520121.6(transcript)|go:""GO:0003707""(nuclear steroid receptor activity)|go:""GO:0005496""(steroid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0012505""(endomembrane system)|go:""GO:0015232""(heme transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0060612""(adipose tissue development)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|interpro:IPR050577|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9707616|panther:PTHR10281(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q00325	intact:EBI-10726177	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|uniprotkb:Q7Z7N7|uniprotkb:B3KS34|ensembl:ENSP00000228318.3|ensembl:ENSP00000447310.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:s25a3_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Phosphate carrier protein, mitochondrial(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"panther:PTHR45671(orthology-group)|ensembl:ENSG00000075415.15(gene)|ensembl:ENST00000228318.8(transcript)|ensembl:ENST00000551917.5(transcript)|go:""GO:0005315""(phosphate transmembrane transporter activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0015317""(""phosphate:proton symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0035435""(phosphate ion transmembrane transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990547""(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|efo:""Orphanet:91130"""	-	-	crc64:78714C85931B22D5	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q13011	intact:EBI-10726177	intact:EBI-711968|uniprotkb:Q8WVX0|uniprotkb:Q96EZ9|ensembl:ENSP00000221418.3|ensembl:ENSP00000489530.1|uniprotkb:A8K745	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:ech1_human(display_long)|uniprotkb:ECH1(gene name)|psi-mi:ECH1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000104823.9(gene)|ensembl:ENSG00000282853.2(gene)|ensembl:ENST00000221418.9(transcript)|ensembl:ENST00000634245.2(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0016020""(membrane)|go:""GO:0051750""(""delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity"")|go:""GO:0070062""(extracellular exosome)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|interpro:IPR045002|mint:Q13011|rcsb pdb:2VRE|rcsb pdb:8SK6|reactome:R-HSA-9033241|reactome:R-HSA-9837999|refseq:NP_001389.2|panther:PTHR43149(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:gh0bwdUu9tkSTHWuySCaTXIQGzI9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P21796	intact:EBI-10726177	intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|ensembl:ENSP00000265333.3|ensembl:ENSP00000378484.3|ensembl:ENSP00000378487.2|uniprotkb:B3KVK4|uniprotkb:D3DQ93	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym)|uniprotkb:Voltage-dependent anion-selective channel protein 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000213585.11(gene)|ensembl:ENST00000265333.8(transcript)|ensembl:ENST00000395044.7(transcript)|ensembl:ENST00000395047.6(transcript)|go:""GO:0001662""(behavioral fear response)|go:""GO:0005244""(voltage-gated monoatomic ion channel activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005757""(mitochondrial permeability transition pore complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006820""(monoatomic anion transport)|go:""GO:0006869""(lipid transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007270""(neuron-neuron synaptic transmission)|go:""GO:0007612""(learning)|go:""GO:0008142""(oxysterol binding)|go:""GO:0008308""(voltage-gated monoatomic anion channel activity)|go:""GO:0015288""(porin activity)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0036444""(calcium import into the mitochondrion)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0046930""(pore complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097001""(ceramide binding)|go:""GO:0110099""(negative regulation of calcium import into the mitochondrion)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1990542""(mitochondrial transmembrane transport)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|rcsb pdb:7QI2|rcsb pdb:8J0O|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215|refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|panther:PTHR11743(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P68371	intact:EBI-10726177	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289.4	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:65""|ensembl:ENSG00000188229.6(gene)|ensembl:ENST00000340384.5(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0005879""(axonemal microtubule)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0036126""(sperm flagellum)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0045171""(intercellular bridge)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072686""(mitotic spindle)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|rcsb pdb:7UN1|rcsb pdb:7UNG|rcsb pdb:8J07|rcsb pdb:8SH7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9833482|refseq:NP_006079.1|panther:PTHR11588(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P08195	intact:EBI-10726177	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122.2|intact:EBI-21352943|uniprotkb:J3KPF3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:4F2 cell-surface antigen heavy chain(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003.19(gene)|ensembl:ENST00000377890.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015821""(methionine transport)|go:""GO:0015823""(phenylalanine transport)|go:""GO:0015824""(proline transport)|go:""GO:0015827""(tryptophan transport)|go:""GO:0015828""(tyrosine transport)|go:""GO:0015829""(valine transport)|go:""GO:0016020""(membrane)|rcsb pdb:8QEY|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|rcsb pdb:8WNS|rcsb pdb:8WNT|rcsb pdb:8WNY|rcsb pdb:8XPU|go:""GO:0042470""(melanosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0044225""(apical pole of neuron)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0070327""(thyroid hormone transport)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1902024""(L-histidine transport)|go:""GO:1903801""(L-leucine import across plasma membrane)|go:""GO:1904273""(L-alanine import across plasma membrane)|go:""GO:1990184""(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7B00|rcsb pdb:7CCS|rcsb pdb:7CMH|rcsb pdb:7CMI|rcsb pdb:7DF1|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|rcsb pdb:7EPZ|rcsb pdb:7P9U|rcsb pdb:7P9V|rcsb pdb:8A6L|rcsb pdb:8G0M|rcsb pdb:8IDA|rcsb pdb:8J8L|rcsb pdb:8J8M|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240|panther:PTHR46673(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9NQC3	intact:EBI-10726177	intact:EBI-715945|intact:EBI-1753019|uniprotkb:Q9Y2Y7|uniprotkb:O94962|uniprotkb:Q9BXG5|uniprotkb:Q9H212|uniprotkb:Q9H3I3|uniprotkb:Q9UQ42|uniprotkb:Q9Y293|uniprotkb:Q9Y5U6|intact:EBI-1958210|intact:EBI-1056082|uniprotkb:Q7L7Q8|uniprotkb:Q96B16|intact:EBI-28967519|uniprotkb:Q7L7Q5|uniprotkb:Q7L7Q6|uniprotkb:Q8IUA4|ensembl:ENSP00000337838.6	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:rtn4_human(display_long)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:XP_005264491.1|refseq:XP_016860007.1|refseq:XP_016860008.1|dip:DIP-42003N|ensembl:ENSG00000115310.19(gene)|ensembl:ENST00000337526.11(transcript)|go:""GO:0001825""(blastocyst formation)|go:""GO:0002523""(leukocyte migration involved in inflammatory response)|go:""GO:0003723""(RNA binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007413""(axonal fasciculation)|go:""GO:0007420""(brain development)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0014069""(postsynaptic density)|go:""GO:0021801""(cerebral cortex radial glia-guided migration)|go:""GO:0022009""(central nervous system vasculogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030517""(negative regulation of axon extension)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0033601""(positive regulation of mammary gland epithelial cell proliferation)|go:""GO:0034165""(positive regulation of toll-like receptor 9 signaling pathway)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0035441""(cell migration involved in vasculogenesis)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050821""(protein stabilization)|go:""GO:0051292""(nuclear pore complex assembly)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0061462""(protein localization to lysosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|go:""GO:0071787""(endoplasmic reticulum tubular network formation)|go:""GO:0090156""(intracellular sphingolipid homeostasis)|go:""GO:0098826""(endoplasmic reticulum tubular network membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0120078""(cell adhesion involved in sprouting angiogenesis)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902430""(negative regulation of amyloid-beta formation)|go:""GO:1902624""(positive regulation of neutrophil migration)|go:""GO:1905523""(positive regulation of macrophage migration)|go:""GO:1905552""(positive regulation of protein localization to endoplasmic reticulum)|go:""GO:1905580""(positive regulation of ERBB3 signaling pathway)|go:""GO:1905653""(positive regulation of artery morphogenesis)|go:""GO:1990809""(endoplasmic reticulum tubular network membrane organization)|go:""GO:2000172""(regulation of branching morphogenesis of a nerve)|go:""GO:2000347""(positive regulation of hepatocyte proliferation)|go:""GO:2001213""(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|interpro:IPR046964|mint:Q9NQC3|rcsb pdb:2G31|rcsb pdb:2JV5|reactome:R-HSA-193634|refseq:NP_001308788.1|refseq:NP_001308789.1|refseq:NP_001308790.1|refseq:NP_001308791.1|refseq:NP_001308792.1|refseq:NP_001308833.1|refseq:NP_008939.1|refseq:NP_065393.1|refseq:NP_722550.1|refseq:NP_997403.1|refseq:NP_997404.1|panther:PTHR45799(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:uhivTNOPdC7+q81CliY0Ozu0EwA9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q02978	intact:EBI-10726177	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|uniprotkb:F5GY65|ensembl:ENSP00000225665.7	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:29072""|ensembl:ENSG00000108528.14(gene)|ensembl:ENST00000225665.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006869""(lipid transport)|go:""GO:0015116""(sulfate transmembrane transporter activity)|go:""GO:0015117""(thiosulfate transmembrane transporter activity)|go:""GO:0015131""(oxaloacetate transmembrane transporter activity)|go:""GO:0015140""(malate transmembrane transporter activity)|go:""GO:0015141""(succinate transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015367""(""oxoglutarate:malate antiporter activity"")|go:""GO:0015709""(thiosulfate transport)|go:""GO:0015729""(oxaloacetate transport)|go:""GO:0035435""(phosphate ion transmembrane transport)|go:""GO:0043490""(malate-aspartate shuttle)|go:""GO:0071422""(succinate transmembrane transport)|go:""GO:0071423""(malate transmembrane transport)|go:""GO:1902358""(sulfate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR050391|mint:Q02978|reactome:R-HSA-428643|reactome:R-HSA-9856872|refseq:NP_003553.2|panther:PTHR45618(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P00492	intact:EBI-10726177	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556.7	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000165704.15(gene)|ensembl:ENST00000298556.8(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001975""(response to amphetamine)|go:""GO:0004422""(hypoxanthine phosphoribosyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006166""(purine ribonucleoside salvage)|go:""GO:0006178""(guanine salvage)|go:""GO:0007625""(grooming behavior)|go:""GO:0007626""(locomotory behavior)|go:""GO:0021756""(striatum development)|go:""GO:0021895""(cerebral cortex neuron differentiation)|go:""GO:0021954""(central nervous system neuron development)|go:""GO:0032263""(GMP salvage)|go:""GO:0032264""(IMP salvage)|go:""GO:0042417""(dopamine metabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043103""(hypoxanthine salvage)|go:""GO:0044209""(AMP salvage)|go:""GO:0045964""(positive regulation of dopamine metabolic process)|go:""GO:0046038""(GMP catabolic process)|go:""GO:0046040""(IMP metabolic process)|go:""GO:0046083""(adenine metabolic process)|go:""GO:0046100""(hypoxanthine metabolic process)|go:""GO:0046651""(lymphocyte proliferation)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0052657""(guanine phosphoribosyltransferase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071542""(dopaminergic neuron differentiation)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|interpro:IPR050408|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|rcsb pdb:7SAN|rcsb pdb:8TPY|reactome:R-HSA-74217|reactome:R-HSA-9734281|reactome:R-HSA-9748787|refseq:NP_000185.1|efo:""Orphanet:510""|efo:""Orphanet:79233""|panther:PTHR43340(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P04637	intact:EBI-10726177	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5|ensembl:ENSP00000269305.4|ensembl:ENSP00000391478.2|ensembl:ENSP00000424104.2|ensembl:ENSP00000426252.2|ensembl:ENSP00000519624.1|ensembl:ENSP00000519626.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:1333""|efo:""Orphanet:145""|efo:""Orphanet:1501""|efo:""Orphanet:210159""|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:251899""|efo:""Orphanet:2807""|efo:""Orphanet:293199""|efo:""Orphanet:3318""|efo:""Orphanet:524""|efo:""Orphanet:585909""|efo:""Orphanet:668""|efo:""Orphanet:67038""|efo:""Orphanet:70573""|efo:""Orphanet:96253""|efo:""Orphanet:99756""|efo:""Orphanet:99757""|panther:PTHR11447(orthology-group)|efo:""Orphanet:52688""|ensembl:ENSG00000141510.19(gene)|ensembl:ENST00000269305.9(transcript)|ensembl:ENST00000445888.6(transcript)|ensembl:ENST00000503591.2(transcript)|ensembl:ENST00000508793.6(transcript)|ensembl:ENST00000714357.1(transcript)|ensembl:ENST00000714359.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000423""(mitophagy)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001094""(TFIID-class transcription factor complex binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001756""(somitogenesis)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0002020""(protease binding)|go:""GO:0002039""(p53 binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002309""(T cell proliferation involved in immune response)|go:""GO:0002326""(B cell lineage commitment)|go:""GO:0002360""(T cell lineage commitment)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005507""(copper ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005657""(replication fork)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006914""(autophagy)|go:""GO:0006974""(DNA damage response)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0006978""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:0006983""(ER overload response)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007369""(gastrulation)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007406""(negative regulation of neuroblast proliferation)|go:""GO:0008104""(protein localization)|go:""GO:0008156""(negative regulation of DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0009299""(mRNA transcription)|go:""GO:0009303""(rRNA transcription)|go:""GO:0009651""(response to salt stress)|go:""GO:0010165""(response to X-ray)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010659""(cardiac muscle cell apoptotic process)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016032""(viral process)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016605""(PML body)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019661""(glucose catabolic process to lactate via pyruvate)|go:""GO:0019899""(enzyme binding)|go:""GO:0021549""(cerebellum development)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034103""(regulation of tissue remodeling)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035033""(histone deacetylase regulator activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035794""(positive regulation of mitochondrial membrane permeability)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036310""(ATP-dependent DNA/DNA annealing activity)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043073""(germ cell nucleus)|go:""GO:0043153""(entrainment of circadian clock by photoperiod)|go:""GO:0043504""(mitochondrial DNA repair)|go:""GO:0043516""(regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045899""(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048512""(circadian behavior)|go:""GO:0048539""(bone marrow development)|go:""GO:0048568""(embryonic organ development)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051097""(negative regulation of helicase activity)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051276""(chromosome organization)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070242""(thymocyte apoptotic process)|go:""GO:0070245""(positive regulation of thymocyte apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071494""(cellular response to UV-C)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0072331""(signal transduction by p53 class mediator)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0072717""(cellular response to actinomycin D)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090399""(replicative senescence)|go:""GO:0090403""(oxidative stress-induced premature senescence)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097252""(oligodendrocyte apoptotic process)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901525""(negative regulation of mitophagy)|go:""GO:1902108""(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902253""(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:1902749""(regulation of cell cycle G2/M phase transition)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903451""(negative regulation of G1 to G0 transition)|go:""GO:1903799""(negative regulation of miRNA processing)|go:""GO:1904024""(negative regulation of glucose catabolic process to lactate via pyruvate)|go:""GO:1905856""(negative regulation of pentose-phosphate shunt)|go:""GO:1990144""(intrinsic apoptotic signaling pathway in response to hypoxia)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000269""(regulation of fibroblast apoptotic process)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2000647""(negative regulation of stem cell proliferation)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872(""p53 transactivation domain (TAD)"")|interpro:IPR036674|interpro:IPR040926|mint:P04637|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|rcsb pdb:2AHI|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3Q06|rcsb pdb:3SAK|rcsb pdb:3TG5|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGL|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:5BUA|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6XRE|rcsb pdb:6ZNC|rcsb pdb:7B46|rcsb pdb:7B47|rcsb pdb:7B48|rcsb pdb:7B49|rcsb pdb:7B4A|rcsb pdb:7B4B|rcsb pdb:7B4C|rcsb pdb:7B4D|rcsb pdb:7B4E|rcsb pdb:7B4F|rcsb pdb:7B4G|rcsb pdb:7B4H|rcsb pdb:7B4N|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7DVD|rcsb pdb:7EAX|rcsb pdb:7EDS|rcsb pdb:7EEU|rcsb pdb:7EL4|rcsb pdb:7NMI|rcsb pdb:7RM4|rcsb pdb:7V97|rcsb pdb:7XZX|rcsb pdb:7XZZ|rcsb pdb:7YGI|rcsb pdb:8A31|rcsb pdb:8A32|rcsb pdb:8A92|rcsb pdb:8CG7|rcsb pdb:8DC4|rcsb pdb:8DC6|rcsb pdb:8DC7|rcsb pdb:8DC8|rcsb pdb:8E7A|rcsb pdb:8E7B|rcsb pdb:8F2H|rcsb pdb:8F2I|rcsb pdb:8GCR|rcsb pdb:8HLL|rcsb pdb:8HLM|rcsb pdb:8HLN|rcsb pdb:8J8N|rcsb pdb:8OXM|rcsb pdb:8OXO|rcsb pdb:8QWK|rcsb pdb:8QWL|rcsb pdb:8QWM|rcsb pdb:8QWN|rcsb pdb:8QWO|rcsb pdb:8QWP|rcsb pdb:8R1F|rcsb pdb:8R1G|rcsb pdb:8UQR|rcsb pdb:8WD2|rcsb pdb:8XP5|rcsb pdb:9C5S|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-9723905|reactome:R-HSA-9725370|reactome:R-HSA-9758274|reactome:R-HSA-9819196|reactome:R-HSA-983231|reactome:R-HSA-9833482|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|refseq:NP_001119590.1|refseq:NP_001263624.1|refseq:NP_001263625.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|ensembl:ENSP00000269305.4|ensembl:ENST00000420246.6|ensembl:ENSP00000391127.2|ensembl:ENSP00000391478.2|ensembl:ENST00000455263.6|ensembl:ENSP00000398846.2|ensembl:ENSP00000426252.2|ensembl:ENST00000504290.5|ensembl:ENSP00000484409.1|ensembl:ENST00000504937.5|ensembl:ENSP00000481179.1|ensembl:ENSP00000424104.2|ensembl:ENST00000509690.6|ensembl:ENSP00000425104.2|ensembl:ENST00000510385.5|ensembl:ENSP00000478499.1|ensembl:ENST00000610292.4|ensembl:ENSP00000478219.1|ensembl:ENST00000610538.4|ensembl:ENSP00000480868.1|ensembl:ENST00000619485.4|ensembl:ENSP00000482537.1|ensembl:ENST00000620739.4|ensembl:ENSP00000481638.1|ensembl:ENST00000622645.4|ensembl:ENSP00000482222.1|ensembl:ENSP00000519624.1|ensembl:ENSP00000519626.1"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P51991	intact:EBI-10726177	intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309.2|ensembl:ENSP00000416340.1|ensembl:ENSP00000503593.1|ensembl:ENSP00000504135.1|ensembl:ENSP00000504152.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144.23(gene)|ensembl:ENST00000392524.7(transcript)|ensembl:ENST00000435711.5(transcript)|ensembl:ENST00000676629.1(transcript)|ensembl:ENST00000678111.1(transcript)|ensembl:ENST00000679159.1(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203|panther:PTHR48026(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P50454	intact:EBI-10726177	intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|intact:EBI-25629313|ensembl:ENSP00000350894.4|ensembl:ENSP00000434412.1|ensembl:ENSP00000434657.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000149257.16(gene)|ensembl:ENST00000358171.8(transcript)|ensembl:ENST00000524558.5(transcript)|ensembl:ENST00000533603.5(transcript)|go:""GO:0003433""(chondrocyte development involved in endochondral bone morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0032964""(collagen biosynthetic process)|go:""GO:0045121""(membrane raft)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051604""(protein maturation)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|refseq:NP_001193943.1|refseq:NP_001226.2|refseq:XP_011543629.1|efo:""Orphanet:216812""|panther:PTHR11461(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P53007	intact:EBI-10726177	intact:EBI-359163|uniprotkb:Q9BSK6|uniprotkb:A8K8E8|ensembl:ENSP00000215882.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:txtp_human(display_long)|uniprotkb:SLC25A1(gene name)|psi-mi:SLC25A1(display_short)|uniprotkb:SLC20A3(gene name synonym)|uniprotkb:Citrate transport protein(gene name synonym)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 1(gene name synonym)|uniprotkb:Mitochondrial citrate carrier(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:356978""|efo:""Orphanet:98914""|ensembl:ENSG00000100075.10(gene)|ensembl:ENST00000215882.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006843""(mitochondrial citrate transmembrane transport)|go:""GO:0015137""(citrate transmembrane transporter activity)|go:""GO:0015142""(tricarboxylic acid transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071913""(citrate secondary active transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|interpro:IPR049563|mint:P53007|reactome:R-HSA-428643|refseq:NP_005975.1|panther:PTHR45788(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:MB0RrMAQme4F8M4IivU1AqUxlgA9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q7KZF4	intact:EBI-10726177	intact:EBI-1044112|uniprotkb:Q13122|uniprotkb:Q96AG0|ensembl:ENSP00000346762.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_055205.2|dip:DIP-29613N|rcsb pdb:3BDL|ensembl:ENSG00000197157.11(gene)|ensembl:ENST00000354725.8(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0010564""(regulation of cell cycle process)|go:""GO:0010587""(miRNA catabolic process)|go:""GO:0016020""(membrane)|rcsb pdb:3OMC|go:""GO:0016894""(endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031332""(RNAi effector complex)|go:""GO:0042470""(melanosome)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097433""(dense body)|go:""GO:1905172""(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071(""Staphylococcal nuclease (SNase-like), OB-fold"")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|interpro:IPR047386|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|rcsb pdb:7KNW|rcsb pdb:7KNX|reactome:R-HSA-6802952|panther:PTHR12302(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9H9B4	intact:EBI-10726177	intact:EBI-355861|uniprotkb:Q9HA53|uniprotkb:B3KPW3|uniprotkb:D3DQN2|ensembl:ENSP00000316905.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:sfxn1_human(display_long)|uniprotkb:SFXN1(gene name)|psi-mi:SFXN1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_073591.2|ensembl:ENSG00000164466.13(gene)|ensembl:ENST00000321442.10(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0006826""(iron ion transport)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0015180""(L-alanine transmembrane transporter activity)|go:""GO:0015194""(L-serine transmembrane transporter activity)|go:""GO:0015808""(L-alanine transport)|go:""GO:0015825""(L-serine transport)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0140300""(serine import into mitochondrion)|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q9H9B4|refseq:NP_001309906.1|panther:PTHR11153(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:n/i6d8Rt+xMOvu3BrZfc0VP0+Wk9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P18031	intact:EBI-10726177	intact:EBI-968788|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4|ensembl:ENSP00000360683.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N|ensembl:ENSG00000196396.10(gene)|ensembl:ENST00000371621.5(transcript)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0003723""(RNA binding)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0009968""(negative regulation of signal transduction)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030162""(regulation of proteolysis)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031904""(endosome lumen)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033157""(regulation of intracellular protein transport)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035791""(platelet-derived growth factor receptor-beta signaling pathway)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045296""(cadherin binding)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071732""(cellular response to nitric oxide)|go:""GO:0097443""(sorting endosome)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903896""(positive regulation of IRE1-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904753""(negative regulation of vascular associated smooth muscle cell migration)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990264""(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:""GO:2000353""(positive regulation of endothelial cell apoptotic process)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1AAX|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2F6Z|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:2NT7|rcsb pdb:2NTA|rcsb pdb:2QBP|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2QBS|rcsb pdb:2VEU|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2ZMM|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:3EB1|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QDV|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:6OMY|rcsb pdb:6PFW|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:6XE8|rcsb pdb:6XEF|rcsb pdb:6XEA|rcsb pdb:6XED|rcsb pdb:6XEE|rcsb pdb:6XEG|rcsb pdb:7FQM|rcsb pdb:7FQN|rcsb pdb:7FQO|rcsb pdb:7FQP|rcsb pdb:7FQQ|rcsb pdb:7FQR|rcsb pdb:7FQS|rcsb pdb:7FQT|rcsb pdb:7FQU|rcsb pdb:7FQV|rcsb pdb:7FQW|rcsb pdb:7FQX|rcsb pdb:7FQY|rcsb pdb:7FQZ|rcsb pdb:7FRE|rcsb pdb:7FRF|rcsb pdb:7FRG|rcsb pdb:7FRH|rcsb pdb:7FRI|rcsb pdb:7FRJ|rcsb pdb:7FRK|rcsb pdb:7FRL|rcsb pdb:7FRM|rcsb pdb:7FRN|rcsb pdb:7FRO|rcsb pdb:7FRP|rcsb pdb:7FRQ|rcsb pdb:7FRR|rcsb pdb:7FRS|rcsb pdb:7FRT|rcsb pdb:7FRU|rcsb pdb:7GS7|rcsb pdb:7GS8|rcsb pdb:7GS9|rcsb pdb:7GSA|rcsb pdb:7GSB|rcsb pdb:7GSC|rcsb pdb:7GSD|rcsb pdb:7GSE|rcsb pdb:7GSF|rcsb pdb:7GSG|rcsb pdb:7GSH|rcsb pdb:7GSI|rcsb pdb:7GSJ|rcsb pdb:7GSK|rcsb pdb:7GSL|rcsb pdb:7GSM|rcsb pdb:7GSN|rcsb pdb:7GSO|rcsb pdb:7GSQ|rcsb pdb:7GSR|rcsb pdb:7GST|rcsb pdb:7GSU|rcsb pdb:7GSV|rcsb pdb:7GSW|rcsb pdb:7GSX|rcsb pdb:7GSY|rcsb pdb:7GSZ|rcsb pdb:7GT0|rcsb pdb:7GT1|rcsb pdb:7GT2|rcsb pdb:7GT3|rcsb pdb:7GT4|rcsb pdb:7GT5|rcsb pdb:7GTI|rcsb pdb:7GT6|rcsb pdb:7GT7|rcsb pdb:7GT8|rcsb pdb:7GT9|rcsb pdb:7GTA|rcsb pdb:7GTB|rcsb pdb:7GTC|rcsb pdb:7GTD|rcsb pdb:7GTE|rcsb pdb:7GTF|rcsb pdb:7GTG|rcsb pdb:7GTH|rcsb pdb:7GTJ|rcsb pdb:7GTK|rcsb pdb:7GTL|rcsb pdb:7GTM|rcsb pdb:7GTN|rcsb pdb:7GTO|rcsb pdb:7GTP|rcsb pdb:7GTQ|rcsb pdb:7GTR|rcsb pdb:7GTS|rcsb pdb:7GTT|rcsb pdb:7GTU|rcsb pdb:7GTV|rcsb pdb:7GTW|rcsb pdb:7GTX|rcsb pdb:7GTY|rcsb pdb:7GTZ|rcsb pdb:7GU0|rcsb pdb:7GU1|rcsb pdb:7GU2|rcsb pdb:7GU3|rcsb pdb:7GU4|rcsb pdb:7GU5|rcsb pdb:7GU6|rcsb pdb:7GU7|rcsb pdb:7GU8|rcsb pdb:7GU9|rcsb pdb:7GUA|rcsb pdb:7GUB|rcsb pdb:7GUC|rcsb pdb:7KEN|rcsb pdb:7KEY|rcsb pdb:7KLX|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MKZ|rcsb pdb:7MM1|rcsb pdb:7MN7|rcsb pdb:7MN9|rcsb pdb:7MNA|rcsb pdb:7MNB|rcsb pdb:7MNC|rcsb pdb:7MND|rcsb pdb:7MNE|rcsb pdb:7MNF|rcsb pdb:7MOU|rcsb pdb:7MOV|rcsb pdb:7MOW|rcsb pdb:7RIN|rcsb pdb:7S4F|rcsb pdb:8DU7|rcsb pdb:8EXI|rcsb pdb:8EXJ|rcsb pdb:8EXK|rcsb pdb:8EXM|rcsb pdb:8EXN|rcsb pdb:8EYA|rcsb pdb:8EYB|rcsb pdb:8EYC|rcsb pdb:8F88|rcsb pdb:8G65|rcsb pdb:8G67|rcsb pdb:8G68|rcsb pdb:8G69|rcsb pdb:8G6A|rcsb pdb:8SKL|rcsb pdb:8U1E|rcsb pdb:8XOY|rcsb pdb:9C66|rcsb pdb:9CYO|rcsb pdb:9CYP|rcsb pdb:9CYQ|rcsb pdb:9CYR|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-77387|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-9860927|panther:PTHR46047(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q12959	intact:EBI-10726177	intact:EBI-357481|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21|ensembl:ENSP00000391732.2|ensembl:ENSP00000407531.1|ensembl:ENSP00000499437.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:199306""|ensembl:ENSG00000075711.21(gene)|ensembl:ENST00000419354.5(transcript)|ensembl:ENST00000448528.6(transcript)|ensembl:ENST00000670935.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001658""(branching involved in ureteric bud morphogenesis)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0001772""(immunological synapse)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0002088""(lens development in camera-type eye)|go:""GO:0004385""(guanylate kinase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0005604""(basement membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007399""(nervous system development)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0014704""(intercalated disc)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030054""(cell junction)|go:""GO:0030432""(peristalsis)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031253""(cell projection membrane)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0031579""(membrane raft organization)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031641""(regulation of myelination)|go:""GO:0033268""(node of Ranvier)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042383""(sarcolemma)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042982""(amyloid precursor protein metabolic process)|go:""GO:0043005""(neuron projection)|go:""GO:0043113""(receptor clustering)|go:""GO:0043219""(lateral loop)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048608""(reproductive structure development)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0048745""(smooth muscle tissue development)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0051660""(establishment of centrosome localization)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060022""(hard palate development)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0097016""(L27 domain binding)|go:""GO:0097025""(MPP7-DLG1-LIN7 complex)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097120""(receptor localization to synapse)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0098915""(membrane repolarization during ventricular cardiac muscle cell action potential)|go:""GO:0098919""(structural constituent of postsynaptic density)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099645""(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:1902305""(regulation of sodium ion transmembrane transport)|go:""GO:1902473""(regulation of protein localization to synapse)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903286""(regulation of potassium ion import)|go:""GO:1903753""(negative regulation of p38MAPK cascade)|go:""GO:1903764""(regulation of potassium ion export across plasma membrane)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313(""Membrane-associated guanylate kinase (MAGUK) scaffold protein"")|interpro:IPR019583|interpro:IPR036034|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036892|interpro:IPR050614|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|rcsb pdb:7PC3|rcsb pdb:8CN1|rcsb pdb:8CN3|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_001277912.1|refseq:NP_004078.2|refseq:XP_005269346.1|refseq:XP_011510804.1|refseq:XP_011510805.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861299.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|panther:PTHR23119(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P12236	intact:EBI-10726177	intact:EBI-356254|uniprotkb:Q96C49|ensembl:ENSP00000370808.5|ensembl:ENSP00000518609.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001627.2|ensembl:ENSG00000169100.14(gene)|ensembl:ENSG00000292334.1(gene)|ensembl:ENST00000381401.11(transcript)|ensembl:ENST00000711214.1(transcript)|go:""GO:0005471""(""ATP:ADP antiporter activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005744""(TIM23 mitochondrial import inner membrane translocase complex)|go:""GO:0006915""(apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0140021""(mitochondrial ADP transmembrane transport)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1990544""(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|reactome:R-HSA-9837999|panther:PTHR45635(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P35080	intact:EBI-10726177	intact:EBI-473138|uniprotkb:Q8WVF9|uniprotkb:Q9HBK2|uniprotkb:B2R4C8|uniprotkb:Q4VBQ4|uniprotkb:D3DNI4|ensembl:ENSP00000239940.7	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:prof2_human(display_long)|uniprotkb:PFN2(gene name)|psi-mi:PFN2(display_short)|uniprotkb:Profilin II(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_002619.1|refseq:NP_444252.1|ensembl:ENSG00000070087.15(gene)|ensembl:ENST00000239940.12(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0003785""(actin monomer binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0010633""(negative regulation of epithelial cell migration)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030837""(negative regulation of actin filament polymerization)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032233""(positive regulation of actin filament bundle assembly)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0050821""(protein stabilization)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098885""(modification of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099140""(presynaptic actin cytoskeleton organization)|go:""GO:0099171""(presynaptic modulation of chemical synaptic transmission)|go:""GO:1900028""(negative regulation of ruffle assembly)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|interpro:IPR048278|mint:P35080|rcsb pdb:1D1J|reactome:R-HSA-376176|reactome:R-HSA-5663220|panther:PTHR13936(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:064T9afVEb7WrgJPLVbKByJDUXc9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:O95292	intact:EBI-10726177	intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"panther:PTHR10809(orthology-group)|dip:DIP-39816N|efo:""Orphanet:209335""|efo:""Orphanet:803""|ensembl:ENSG00000124164.16(gene)|ensembl:ENST00000475243.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019899""(enzyme binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0044830""(modulation by host of viral RNA genome replication)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046725""(negative regulation by virus of viral protein levels in host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0090114""(COPII-coated vesicle budding)|go:""GO:0090158""(endoplasmic reticulum membrane organization)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|refseq:NP_001182606.1|refseq:NP_004729.1"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P04843	intact:EBI-10726177	intact:EBI-355963|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0|ensembl:ENSP00000296255.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:402020""|ensembl:ENSG00000163902.12(gene)|ensembl:ENST00000296255.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0042470""(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_002941.1|dip:DIP-38152N|panther:PTHR21049(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q16527	intact:EBI-10726177	intact:EBI-2959737|uniprotkb:Q93030|ensembl:ENSP00000310901.5|ensembl:ENSP00000450056.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:csrp2_human(display_long)|uniprotkb:CSRP2(gene name)|psi-mi:CSRP2(display_short)|uniprotkb:LMO5(gene name synonym)|uniprotkb:SMLIM(gene name synonym)|uniprotkb:Cysteine-rich protein 2(gene name synonym)|uniprotkb:LIM domain only protein 5(gene name synonym)|uniprotkb:Smooth muscle cell LIM protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001312.1|refseq:NP_001287894.1|ensembl:ENSG00000175183.10(gene)|ensembl:ENST00000311083.10(transcript)|ensembl:ENST00000546966.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0030018""(Z disc)|go:""GO:0030154""(cell differentiation)|go:""GO:0042805""(actinin binding)|go:""GO:0045214""(sarcomere organization)|go:""GO:0046872""(metal ion binding)|go:""GO:0060537""(muscle tissue development)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q16527|panther:PTHR24215(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:nyQ01E4UJb21IE/mZhZjXakJoyo9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P00367	intact:EBI-10726177	intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865.4|uniprotkb:B3KV55|uniprotkb:B4DGN5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:35878""|ensembl:ENSG00000148672.10(gene)|ensembl:ENST00000277865.5(transcript)|go:""GO:0004352""(""glutamate dehydrogenase (NAD+) activity"")|go:""GO:0004353""(""glutamate dehydrogenase [NAD(P)+] activity"")|go:""GO:0004354""(""glutamate dehydrogenase (NADP+) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006538""(glutamate catabolic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043531""(ADP binding)|go:""GO:0070403""(NAD+ binding)|go:""GO:0070728""(L-leucine binding)|go:""GO:0072350""(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|interpro:IPR046346|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|rcsb pdb:7UZM|rcsb pdb:8KGY|rcsb pdb:8SK8|rcsb pdb:8W4J|reactome:R-HSA-2151201|reactome:R-HSA-8964539|reactome:R-HSA-9837999|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|refseq:NP_005262.1|panther:PTHR11606(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P84103	intact:EBI-10726177	intact:EBI-372557|uniprotkb:P23152|uniprotkb:O08831|uniprotkb:B4E241|ensembl:ENSP00000362820.5|ensembl:ENSP00000482833.1|intact:EBI-11020748|uniprotkb:Q5R3K0	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:srsf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP20(gene name synonym)|uniprotkb:SRSF3(gene name)|psi-mi:SRSF3(display_short)|uniprotkb:SRP20(gene name synonym)|uniprotkb:SFRS3(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000112081.18(gene)|ensembl:ENST00000373715.11(transcript)|ensembl:ENST00000620941.2(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0031053""(primary miRNA processing)|go:""GO:0043274""(phospholipase binding)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0070878""(primary miRNA binding)|go:""GO:0160134""(protein-RNA sequence-specific adaptor activity)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR050907|mint:P84103|rcsb pdb:2I2Y|rcsb pdb:2I38|rcsb pdb:9ASQ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|panther:PTHR23147(orthology-group)|refseq:NP_003008.1|dip:DIP-32961N"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:BcfyCj2cNNTH1igANKpvh4IHDVU9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P14625	intact:EBI-10726177	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767.4	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)|uniprotkb:HSPC4(gene name synonym)|uniprotkb:Heat shock protein family C member 4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"panther:PTHR11528(orthology-group)|refseq:NP_003290.1|ensembl:ENSG00000166598.16(gene)|ensembl:ENST00000299767.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030496""(midbody)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|reactome:R-HSA-8957275|go:""GO:0031247""(actin rod assembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033018""(sarcoplasmic reticulum lumen)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042470""(melanosome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051208""(sequestering of calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071287""(cellular response to manganese ion)|go:""GO:0071318""(cellular response to ATP)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|rcsb pdb:7ULL|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|dip:DIP-36060N"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q15084	intact:EBI-10726177	intact:EBI-1043087|uniprotkb:Q6ZSH5|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7|ensembl:ENSP00000272227.4	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|refseq:NP_005733.1|ensembl:ENSG00000143870.13(gene)|ensembl:ENST00000272227.8(transcript)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006457""(protein folding)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0070062""(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|rcsb pdb:8CPQ|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|panther:PTHR45815(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:O00161	intact:EBI-10726177	intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_003816.2|refseq:NP_570710.1|refseq:XP_016878183.1|ensembl:ENSG00000092531.10(gene)|ensembl:ENST00000249647.8(transcript)|go:""GO:0002553""(histamine secretion by mast cell)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006887""(exocytosis)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006903""(vesicle targeting)|go:""GO:0015031""(protein transport)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042581""(specific granule)|go:""GO:0042582""(azurophil granule)|go:""GO:0043005""(neuron projection)|go:""GO:0061025""(membrane fusion)|go:""GO:0070032""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0098793""(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR19305(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P11586	intact:EBI-10726177	intact:EBI-709638|uniprotkb:Q86VC9|uniprotkb:Q9BVP5|uniprotkb:B2R5Y2|uniprotkb:G3V2B8|ensembl:ENSP00000498336.1|ensembl:ENSP00000498511.1|intact:EBI-21358459|uniprotkb:A0A024R652|uniprotkb:A0A384N5Y3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:c1tc_human(display_long)|uniprotkb:MTHFD1(gene name)|psi-mi:MTHFD1(display_short)|uniprotkb:MTHFC(gene name synonym)|uniprotkb:MTHFD(gene name synonym)|uniprotkb:Epididymis secretory sperm binding protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:658813""|dip:DIP-33682N|ensembl:ENSG00000100714.18(gene)|ensembl:ENST00000651537.1(transcript)|ensembl:ENST00000652337.1(transcript)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001843""(neural tube closure)|go:""GO:0004329""(formate-tetrahydrofolate ligase activity)|go:""GO:0004477""(methenyltetrahydrofolate cyclohydrolase activity)|go:""GO:0004486""(""methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity"")|go:""GO:0004487""(""methylenetetrahydrofolate dehydrogenase (NAD+) activity"")|go:""GO:0004488""(""methylenetetrahydrofolate dehydrogenase (NADP+) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006555""(methionine metabolic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0007507""(heart development)|go:""GO:0009069""(serine family amino acid metabolic process)|go:""GO:0009070""(serine family amino acid biosynthetic process)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0009152""(purine ribonucleotide biosynthetic process)|go:""GO:0009257""(10-formyltetrahydrofolate biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019346""(transsulfuration)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0048702""(embryonic neurocranium morphogenesis)|go:""GO:0048703""(embryonic viscerocranium morphogenesis)|go:""GO:0061053""(somite development)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR020867|interpro:IPR027417|interpro:IPR036291|interpro:IPR046346|mint:P11586|rcsb pdb:1A4I|rcsb pdb:1DIA|rcsb pdb:1DIB|rcsb pdb:1DIG|rcsb pdb:6ECP|rcsb pdb:6ECQ|rcsb pdb:6ECR|reactome:R-HSA-196757|refseq:NP_005947.3|panther:PTHR48099(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:6ZizfpjVcaL5WNxKXL7qJpw59PI9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P51572	intact:EBI-10726177	intact:EBI-77683|uniprotkb:Q13836|uniprotkb:Q96CF0|uniprotkb:D3DWV5|uniprotkb:B3KQ79|ensembl:ENSP00000343458.6|ensembl:ENSP00000494052.1|ensembl:ENSP00000499882.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:bap31_human(display_long)|uniprotkb:BCAP31(gene name)|psi-mi:BCAP31(display_short)|uniprotkb:BAP31(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:6C6-AG tumor-associated antigen(gene name synonym)|uniprotkb:DXS1357E(gene name synonym)|uniprotkb:Protein CDM(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"panther:PTHR12701(orthology-group)|efo:""Orphanet:369939""|efo:""Orphanet:369942""|ensembl:ENSG00000185825.17(gene)|ensembl:ENST00000345046.12(transcript)|ensembl:ENST00000647529.1(transcript)|ensembl:ENST00000672675.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016020""(membrane)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070973""(protein localization to endoplasmic reticulum exit site)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1904154""(positive regulation of retrograde protein transport, ER to cytosol)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:P51572|rcsb pdb:4JZL|rcsb pdb:4JZP|rcsb pdb:8XWX|reactome:R-HSA-111465|reactome:R-HSA-75153|reactome:R-HSA-8980692|reactome:R-HSA-983170|reactome:R-HSA-9833110|refseq:NP_001132913.1|refseq:NP_001132929.1|refseq:NP_001243376.1|refseq:NP_005736.3"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:m0aN00PLZJDWA/K1vEbla1W9+S89606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9NZ01	intact:EBI-10726177	intact:EBI-2877718|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55|ensembl:ENSP00000215567.4	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000099797.15(gene)|ensembl:ENST00000215567.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006665""(sphingolipid metabolic process)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0017099""(very-long-chain fatty acyl-CoA dehydrogenase activity)|go:""GO:0030497""(fatty acid elongation)|go:""GO:0035338""(long-chain fatty-acyl-CoA biosynthetic process)|go:""GO:0042761""(very long-chain fatty acid biosynthetic process)|go:""GO:0102758""(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|interpro:IPR049127|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_001308099.1|refseq:NP_612510.1|efo:""Orphanet:88616""|panther:PTHR10556(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9H2J7	intact:EBI-10726177	intact:EBI-11343466|uniprotkb:E7ESJ5|uniprotkb:B7Z2P7|uniprotkb:A8K592|uniprotkb:Q9H9F5|ensembl:ENSP00000266682.5|ensembl:ENSP00000505286.1|ensembl:ENSP00000505485.1|ensembl:ENSP00000505789.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:s6a15_human(display_long)|uniprotkb:SLC6A15(gene name)|psi-mi:SLC6A15(display_short)|uniprotkb:B0AT2(gene name synonym)|uniprotkb:NTT73(gene name synonym)|uniprotkb:SBAT1(gene name synonym)|uniprotkb:Sodium- and chloride-dependent neurotransmitter transporter NTT73(gene name synonym)|uniprotkb:Sodium-coupled branched-chain amino-acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 6 member 15(gene name synonym)|uniprotkb:Transporter v7-3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001139807.1|refseq:NP_060527.2|refseq:NP_877499.1|panther:PTHR11616(orthology-group)|ensembl:ENSG00000072041.18(gene)|ensembl:ENST00000266682.10(transcript)|ensembl:ENST00000680963.1(transcript)|ensembl:ENST00000681106.1(transcript)|ensembl:ENST00000681721.1(transcript)|go:""GO:0005295""(""neutral L-amino acid:sodium symporter activity"")|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005326""(neurotransmitter transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0006865""(amino acid transport)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015657""(""branched-chain amino acid:sodium symporter activity"")|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0015820""(L-leucine transport)|go:""GO:0015824""(proline transport)|go:""GO:0016020""(membrane)|go:""GO:0035725""(sodium ion transmembrane transport)|interpro:IPR000175(""Sodium:neurotransmitter symporter"")|interpro:IPR002438(""Sodium:neurotransmitter symporter, orphan"")|interpro:IPR037272|interpro:IPR042934|mint:Q9H2J7|reactome:R-HSA-352230|reactome:R-HSA-442660"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:MubTClioe24j6+ldJKeHsmuzg1U9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9Y285	intact:EBI-10726177	intact:EBI-725361|uniprotkb:Q9NSD8|uniprotkb:Q9Y4W8|uniprotkb:B4E363|ensembl:ENSP00000320309.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:syfa_human(display_long)|uniprotkb:CML33(gene name synonym)|uniprotkb:FARSA(gene name)|psi-mi:FARSA(display_short)|uniprotkb:FARS(gene name synonym)|uniprotkb:FARSLA(gene name synonym)|uniprotkb:FARSL(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_004452.1|dip:DIP-53610N|ensembl:ENSG00000179115.11(gene)|ensembl:ENST00000314606.9(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004826""(phenylalanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006432""(phenylalanyl-tRNA aminoacylation)|go:""GO:0009328""(phenylalanine-tRNA ligase complex)|go:""GO:0016020""(membrane)|go:""GO:0051290""(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|interpro:IPR045864|mint:Q9Y285|rcsb pdb:3L4G|reactome:R-HSA-379716|panther:PTHR11538(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:FpOCk4Mzmsb2CnIUwUKg5nRg7/U9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q96AB3	intact:EBI-10726177	intact:EBI-372799|ensembl:ENSP00000401726.1|uniprotkb:Q9H5G0|uniprotkb:Q6ZN91	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:isoc2_human(display_long)|uniprotkb:ISOC2(gene name)|psi-mi:ISOC2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000063241.8(gene)|ensembl:ENST00000425675.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0031648""(protein destabilization)|interpro:IPR000868(Isochorismatase hydrolase)|interpro:IPR036380|interpro:IPR050993|mint:Q96AB3|refseq:NP_001129673.1|refseq:NP_001129674.1|refseq:NP_078986.1|panther:PTHR14119(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:/529kybU6ZrjgYKx6adgIJCb3fE9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P09936	intact:EBI-10726177	intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440.4|ensembl:ENSP00000422542.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000154277.13(gene)|ensembl:ENST00000284440.9(transcript)|ensembl:ENST00000503431.5(transcript)|go:""GO:0002176""(male germ cell proliferation)|go:""GO:0002931""(response to ischemia)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0007412""(axon target recognition)|go:""GO:0007628""(adult walking behavior)|go:""GO:0008242""(omega peptidase activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019896""(axonal transport of mitochondrion)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031694""(alpha-2A adrenergic receptor binding)|go:""GO:0042755""(eating behavior)|go:""GO:0043022""(ribosome binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0050905""(neuromuscular process)|go:""GO:0055001""(muscle cell development)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|rcsb pdb:7ZM0|rcsb pdb:8DY8|rcsb pdb:8EDE|rcsb pdb:8PW1|rcsb pdb:8XI7|reactome:R-HSA-5689603|refseq:NP_004172.2|dip:DIP-36620N|efo:""Orphanet:2828""|efo:""Orphanet:352654""|panther:PTHR10589(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P55265	intact:EBI-10726177	intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459.4	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"dip:DIP-29310N|ensembl:ENSG00000160710.19(gene)|ensembl:ENST00000368474.9(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002566""(somatic diversification of immune receptors via somatic mutation)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003726""(double-stranded RNA adenosine deaminase activity)|go:""GO:0004000""(adenosine deaminase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006382""(adenosine to inosine editing)|go:""GO:0006396""(RNA processing)|go:""GO:0006397""(mRNA processing)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0008251""(tRNA-specific adenosine deaminase activity)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0016553""(base conversion or substitution editing)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0031054""(pre-miRNA processing)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0044530""(supraspliceosomal complex)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0060216""(definitive hemopoiesis)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|go:""GO:0070922""(RISC complex assembly)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098586""(cellular response to virus)|go:""GO:1900369""(negative regulation of post-transcriptional gene silencing by regulatory ncRNA)|go:""GO:1903944""(negative regulation of hepatocyte apoptotic process)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|rcsb pdb:7ZJ1|rcsb pdb:7ZLQ|rcsb pdb:8GBC|rcsb pdb:8GBD|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|reactome:R-HSA-9833482|refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|efo:""Orphanet:225154""|efo:""Orphanet:41""|efo:""Orphanet:51""|panther:PTHR10910(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9NSD9	intact:EBI-10726177	intact:EBI-353803|uniprotkb:B4DFM0|uniprotkb:O95708|uniprotkb:Q9NZZ6|ensembl:ENSP00000281828.6|uniprotkb:Q4ZFX1|uniprotkb:Q57ZJ5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:syfb_human(display_long)|uniprotkb:FARSB(gene name)|psi-mi:FARSB(display_short)|uniprotkb:FARSLB(gene name synonym)|uniprotkb:FRSB(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:HSPC173(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000116120.11(gene)|ensembl:ENST00000281828.8(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004826""(phenylalanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0006432""(phenylalanyl-tRNA aminoacylation)|go:""GO:0009328""(phenylalanine-tRNA ligase complex)|go:""GO:0016020""(membrane)|go:""GO:0051290""(protein heterotetramerization)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|interpro:IPR040659|interpro:IPR041616|interpro:IPR045060|interpro:IPR045864|mint:Q9NSD9|rcsb pdb:3L4G|reactome:R-HSA-379716|refseq:NP_005678.3|refseq:XP_006712232.1|refseq:XP_011508768.1|refseq:XP_016858599.1|efo:""Orphanet:178506""|dip:DIP-32869N|panther:PTHR10947(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:YgMUMEiw+jAUaDK5KomMWi66vn09606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P34897	intact:EBI-10726177	intact:EBI-352908|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43|ensembl:ENSP00000333667.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1|rcsb pdb:5V7I|ensembl:ENSG00000182199.11(gene)|ensembl:ENST00000328923.8(transcript)|go:""GO:0002082""(regulation of oxidative phosphorylation)|go:""GO:0003682""(chromatin binding)|go:""GO:0004372""(glycine hydroxymethyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006544""(glycine metabolic process)|go:""GO:0006563""(L-serine metabolic process)|go:""GO:0006564""(L-serine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008732""(L-allo-threonine aldolase activity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016597""(amino acid binding)|go:""GO:0019264""(glycine biosynthetic process from serine)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0034340""(response to type I interferon)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0042802""(identical protein binding)|go:""GO:0046653""(tetrahydrofolate metabolic process)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070129""(regulation of mitochondrial translation)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0070552""(BRISC complex)|go:""GO:1903715""(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|interpro:IPR049943|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|rcsb pdb:7BYI|rcsb pdb:8AQL|rcsb pdb:8FJT|rcsb pdb:8FJU|rcsb pdb:8GKS|rcsb pdb:8GKT|rcsb pdb:8GKU|rcsb pdb:8GKW|rcsb pdb:8GKY|rcsb pdb:8GKZ|rcsb pdb:8QI7|rcsb pdb:8SSJ|rcsb pdb:8T4O|rcsb pdb:8T4P|rcsb pdb:8TLC|rcsb pdb:9BOX|reactome:R-HSA-196757|reactome:R-HSA-9013408|reactome:R-HSA-9837999|panther:PTHR11680(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q53GQ0	intact:EBI-10726177	intact:EBI-2963255|uniprotkb:A8K9B0|uniprotkb:Q9Y6G8|uniprotkb:Q96JU2|uniprotkb:D3DR23|uniprotkb:Q96EA9|ensembl:ENSP00000278353.4	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:dhb12_human(display_long)|uniprotkb:HSD17B12(gene name)|psi-mi:HSD17B12(display_short)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 12(gene name synonym)|uniprotkb:3-ketoacyl-CoA reductase(gene name synonym)|uniprotkb:SDR12C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 1(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 12(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_057226.1|ensembl:ENSG00000149084.13(gene)|ensembl:ENST00000278353.10(transcript)|go:""GO:0001968""(fibronectin binding)|go:""GO:0004303""(""estradiol 17-beta-dehydrogenase [NAD(P)+] activity"")|go:""GO:0005518""(collagen binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006703""(estrogen biosynthetic process)|go:""GO:0008201""(heparin binding)|go:""GO:0009923""(fatty acid elongase complex)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0019367""(fatty acid elongation, saturated fatty acid)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035338""(long-chain fatty-acyl-CoA biosynthetic process)|go:""GO:0141040""(very-long-chain 3-oxoacyl-CoA reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|interpro:IPR051019|mint:Q53GQ0|reactome:R-HSA-193048|reactome:R-HSA-75876|panther:PTHR43899(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:2R2pFY0c9yRuCvLU2J8n2urR+0o9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P29966	intact:EBI-10726177	intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_002347.5|ensembl:ENSG00000277443.3(gene)|ensembl:ENST00000612661.2(transcript)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006915""(apoptotic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007015""(actin filament organization)|go:""GO:0007417""(central nervous system development)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0021915""(neural tube development)|go:""GO:0022008""(neurogenesis)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042585""(germinal vesicle)|go:""GO:0042802""(identical protein binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997|panther:PTHR14353(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P53985	intact:EBI-10726177	intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|ensembl:ENSP00000358640.4|ensembl:ENSP00000397106.2|ensembl:ENSP00000399104.2|ensembl:ENSP00000416167.2|ensembl:ENSP00000441065.1|ensembl:ENSP00000485688.1|ensembl:ENSP00000486000.1|ensembl:ENSP00000505879.1|uniprotkb:Q49A45	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000155380.13(gene)|ensembl:ENSG00000281917.4(gene)|ensembl:ENST00000369626.8(transcript)|ensembl:ENST00000429288.2(transcript)|ensembl:ENST00000443580.6(transcript)|ensembl:ENST00000458229.6(transcript)|ensembl:ENST00000538576.5(transcript)|ensembl:ENST00000628110.2(transcript)|ensembl:ENST00000630362.4(transcript)|ensembl:ENST00000679803.1(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007098""(centrosome cycle)|go:""GO:0008028""(monocarboxylic acid transmembrane transporter activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0015129""(lactate transmembrane transporter activity)|go:""GO:0015130""(mevalonate transmembrane transporter activity)|go:""GO:0015141""(succinate transmembrane transporter activity)|go:""GO:0015650""(""lactate:proton symporter activity"")|go:""GO:0015718""(monocarboxylic acid transport)|go:""GO:0015728""(mevalonate transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0030054""(cell junction)|go:""GO:0032094""(response to food)|go:""GO:0035879""(plasma membrane lactate transport)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042867""(pyruvate catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0046943""(carboxylic acid transmembrane transporter activity)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0051780""(behavioral response to nutrient)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0071422""(succinate transmembrane transport)|go:""GO:0097159""(obsolete organic cyclic compound binding)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901475""(pyruvate transmembrane transport)|go:""GO:1905039""(carboxylic acid transmembrane transport)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|interpro:IPR050327|mint:P53985|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|rcsb pdb:7YR5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-9749641|refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|efo:""Orphanet:165991""|efo:""Orphanet:171690""|efo:""Orphanet:438075""|panther:PTHR11360(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P31930	intact:EBI-10726177	intact:EBI-1052596|uniprotkb:Q96DD2|uniprotkb:B2R7R8|ensembl:ENSP00000203407.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:qcr1_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 1(gene name synonym)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:UQCRC1(gene name)|psi-mi:UQCRC1(display_short)|uniprotkb:Core protein I(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_003356.2|ensembl:ENSG00000010256.12(gene)|ensembl:ENST00000203407.6(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006122""(mitochondrial electron transport, ubiquinol to cytochrome c)|go:""GO:0008121""(ubiquinol-cytochrome-c reductase activity)|go:""GO:0009060""(aerobic respiration)|go:""GO:0014823""(response to activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043279""(response to alkaloid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045275""(respiratory chain complex III)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|go:""GO:0098803""(respiratory chain complex)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR050361|mint:P31930|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-9865881|panther:PTHR11851(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:7Yrm6OhOmgfHF5mAX3hT3DMGnkc9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P11182	intact:EBI-10726177	intact:EBI-359002|uniprotkb:Q5VVL8|uniprotkb:B2R811|intact:EBI-1058407|ensembl:ENSP00000359151.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	"psi-mi:odb2_human(display_long)|uniprotkb:DBT(gene name)|psi-mi:DBT(display_short)|uniprotkb:BCATE2(gene name synonym)|uniprotkb:""Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase""(gene name synonym)|uniprotkb:Dihydrolipoamide branched chain transacylase(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex(gene name synonym)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase complex component E2(gene name synonym)|uniprotkb:52 kDa mitochondrial autoantigen of primary biliary cirrhosis(gene name synonym)|uniprotkb:Branched chain 2-oxo-acid dehydrogenase complex component E2(gene name synonym)|uniprotkb:BCKDHE2(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:268145""|efo:""Orphanet:268162""|efo:""Orphanet:268173""|efo:""Orphanet:268184""|ensembl:ENSG00000137992.15(gene)|ensembl:ENST00000370132.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016407""(acetyltransferase activity)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|go:""GO:0031405""(lipoic acid binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0043754""(""dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity"")|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|go:""GO:0160157""(branched-chain alpha-ketoacid dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|interpro:IPR050743|mint:P11182|rcsb pdb:1K8M|rcsb pdb:1K8O|rcsb pdb:1ZWV|rcsb pdb:2COO|rcsb pdb:3RNM|reactome:R-HSA-70895|reactome:R-HSA-9013407|reactome:R-HSA-9837999|reactome:R-HSA-9857492|reactome:R-HSA-9859138|reactome:R-HSA-9865113|reactome:R-HSA-9865125|reactome:R-HSA-9907570|reactome:R-HSA-9912481|reactome:R-HSA-9912529|refseq:NP_001909.3|panther:PTHR43178(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:GUKAKuwtHU7k0JHSgC7E8oOKpUk9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P30101	intact:EBI-10726177	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000167004.14(gene)|ensembl:ENST00000300289.10(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004629""(phospholipase C activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0009986""(cell surface)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061779""(Tapasin-ERp57 complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|rcsb pdb:7QNG|rcsb pdb:7QPD|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|refseq:NP_005304.3|dip:DIP-29132N|panther:PTHR18929(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9HCU5	intact:EBI-10726177	intact:EBI-2553896|uniprotkb:Q9UH94|uniprotkb:Q53SZ8|ensembl:ENSP00000260643.2	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:sec12_human(display_long)|uniprotkb:SEC12(gene name synonym)|uniprotkb:PREB(gene name)|psi-mi:PREB(display_short)|uniprotkb:Prolactin regulatory element-binding protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_037520.1|refseq:NP_001317414.1|refseq:NP_001317415.1|ensembl:ENSG00000138073.14(gene)|ensembl:ENST00000260643.7(transcript)|go:""GO:0003400""(regulation of COPII vesicle coating)|go:""GO:0003677""(DNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0016020""(membrane)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0051020""(GTPase binding)|go:""GO:0070971""(endoplasmic reticulum exit site)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR045260|mint:Q9HCU5|rcsb pdb:5TF2|reactome:R-HSA-204005|reactome:R-HSA-381038|reactome:R-HSA-5694530|panther:PTHR23284(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:3xjABrP1KtfZUMb/BSbe8ZN6dJ49606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q15185	intact:EBI-10726177	intact:EBI-1049387|uniprotkb:Q8WU70|intact:EBI-9357271|uniprotkb:B4DHP2|uniprotkb:B4DP11|uniprotkb:B4DP21|uniprotkb:A8K7D0|ensembl:ENSP00000262033.6|intact:EBI-25629407	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:tebp_human(display_long)|uniprotkb:Cytosolic prostaglandin E2 synthase(gene name synonym)|uniprotkb:Telomerase-binding protein p23(gene name synonym)|uniprotkb:Progesterone receptor complex p23(gene name synonym)|uniprotkb:PTGES3(gene name)|psi-mi:PTGES3(display_short)|uniprotkb:P23(gene name synonym)|uniprotkb:TEBP(gene name synonym)|uniprotkb:Hsp90 co-chaperone(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001269530.1|refseq:NP_001269531.1|refseq:NP_001269532.1|refseq:NP_001269533.1|refseq:NP_001269534.1|ensembl:ENSG00000110958.16(gene)|ensembl:ENST00000262033.11(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0003720""(telomerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005697""(telomerase holoenzyme complex)|go:""GO:0005829""(cytosol)|go:""GO:0005978""(glycogen biosynthetic process)|go:""GO:0006457""(protein folding)|go:""GO:0007004""(telomere maintenance via telomerase)|go:""GO:0007165""(signal transduction)|go:""GO:0019371""(cyclooxygenase pathway)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042921""(nuclear receptor-mediated glucocorticoid signaling pathway)|go:""GO:0043588""(skin development)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0050220""(prostaglandin-E synthase activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0060430""(lung saccule development)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1905323""(telomerase holoenzyme complex assembly)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR045250|mint:Q15185|rcsb pdb:1EJF|rcsb pdb:7KRJ|rcsb pdb:7L7I|rcsb pdb:7L7J|reactome:R-HSA-2162123|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|refseq:NP_006592.3|dip:DIP-279N|panther:PTHR22932(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:6NuM7BPG39XzwqdKBCr74uuumCo9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:O75396	intact:EBI-10726177	intact:EBI-1058865|uniprotkb:A8K1G0|ensembl:ENSP00000463393.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_004883.3|ensembl:ENSG00000265808.4(gene)|ensembl:ENST00000578049.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0015031""(protein transport)|go:""GO:0030133""(transport vesicle)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042470""(melanosome)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048280""(vesicle fusion with Golgi apparatus)|go:""GO:1902902""(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:8HR0|reactome:R-HSA-1236974|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|dip:DIP-50458N|panther:PTHR45837(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:DRKtD169T9eYZ2kFufLapidvcKs9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P09622	intact:EBI-10726177	intact:EBI-353366|ensembl:ENSP00000205402.3|ensembl:ENSP00000390667.1|uniprotkb:Q14131|uniprotkb:Q14167|uniprotkb:Q59EV8|uniprotkb:Q8WTS4|uniprotkb:B2R5X0|uniprotkb:B4DHG0|uniprotkb:B4DT69	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:dldh_human(display_long)|uniprotkb:DLD(gene name)|psi-mi:DLD(display_short)|uniprotkb:GCSL(gene name synonym)|uniprotkb:LAD(gene name synonym)|uniprotkb:PHE3(gene name synonym)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Glycine cleavage system L protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000091140.15(gene)|ensembl:ENST00000205402.10(transcript)|ensembl:ENST00000417551.5(transcript)|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006086""(pyruvate decarboxylation to acetyl-CoA)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0006120""(mitochondrial electron transport, NADH to ubiquinone)|go:""GO:0006508""(proteolysis)|go:""GO:0007369""(gastrulation)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0031514""(motile cilium)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0043159""(acrosomal matrix)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|go:""GO:0045254""(pyruvate dehydrogenase complex)|go:""GO:0048240""(sperm capacitation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0160157""(branched-chain alpha-ketoacid dehydrogenase complex)|go:""GO:0160167""(oxoadipate dehydrogenase complex)|go:""GO:1902493""(acetyltransferase complex)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|interpro:IPR050151|mint:P09622|rcsb pdb:1ZMC|rcsb pdb:1ZMD|rcsb pdb:1ZY8|rcsb pdb:2F5Z|rcsb pdb:3RNM|rcsb pdb:5J5Z|rcsb pdb:5NHG|rcsb pdb:6HG8|rcsb pdb:6I4P|rcsb pdb:6I4Q|rcsb pdb:6I4R|rcsb pdb:6I4S|rcsb pdb:6I4T|rcsb pdb:6I4U|rcsb pdb:6I4Z|rcsb pdb:7PSC|rcsb pdb:7ZYT|reactome:R-HSA-204174|reactome:R-HSA-5362517|reactome:R-HSA-6783984|reactome:R-HSA-70895|reactome:R-HSA-9837999|reactome:R-HSA-9853506|reactome:R-HSA-9858328|reactome:R-HSA-9859138|reactome:R-HSA-9861559|reactome:R-HSA-9865113|reactome:R-HSA-9907570|reactome:R-HSA-9912481|reactome:R-HSA-9912529|refseq:NP_000099.2|refseq:NP_001276679.1|refseq:NP_001276680.1|refseq:NP_001276681.1|efo:""Orphanet:2394""|dip:DIP-29027N|panther:PTHR22912(orthology-group)"	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:7613492C516F3835	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:7Yf9KyBWf18686aOXVUwab65rl89606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P49257	intact:EBI-10726177	intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047.4|intact:EBI-21355115	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000074695.6(gene)|ensembl:ENST00000251047.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006457""(protein folding)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007596""(blood coagulation)|go:""GO:0010638""(positive regulation of organelle organization)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0030017""(sarcomere)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903215""(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR051136|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|rcsb pdb:8JP4|rcsb pdb:8JP5|rcsb pdb:8JP6|rcsb pdb:8JP7|rcsb pdb:8JP8|rcsb pdb:8JP9|rcsb pdb:8JPG|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-948021|refseq:NP_005561.1|efo:""Orphanet:35909""|dip:DIP-42188N|panther:PTHR12223(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P24390	intact:EBI-10726177	intact:EBI-1043076|uniprotkb:B2R6N4|uniprotkb:Q54A39|uniprotkb:Q8NBW7|ensembl:ENSP00000329471.2	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:erd21_human(display_long)|uniprotkb:KDELR1(gene name)|psi-mi:KDELR1(display_short)|uniprotkb:ERD2.1(gene name synonym)|uniprotkb:KDEL endoplasmic reticulum protein retention receptor 1(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM23(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_006792.1|dip:DIP-48668N|ensembl:ENSG00000105438.9(gene)|ensembl:ENST00000330720.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005046""(KDEL sequence binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0006621""(protein retention in ER lumen)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0015031""(protein transport)|go:""GO:0030133""(transport vesicle)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030663""(COPI-coated vesicle membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0046923""(ER retention sequence binding)|go:""GO:0070231""(T cell apoptotic process)|interpro:IPR000133(ER lumen protein retaining receptor)|mint:P24390|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR10585(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:V+4Hb765BqjFuT1/ewZWs9gNQ/M9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P04844	intact:EBI-10726177	intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530.6|ensembl:ENSP00000517679.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001129243.1|refseq:NP_002942.2|refseq:NP_001311235.1|refseq:NP_001311234.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1|ensembl:ENSG00000118705.18(gene)|ensembl:ENSG00000291973.1(gene)|ensembl:ENST00000237530.11(transcript)|ensembl:ENST00000709412.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0036211""(protein modification process)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|panther:PTHR12640(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:O95210	intact:EBI-10726177	intact:EBI-2947137|intact:EBI-28977817|uniprotkb:B3KVZ9|ensembl:ENSP00000237642.6	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:stbd1_human(display_long)|uniprotkb:STBD1(gene name)|psi-mi:STBD1(display_short)|uniprotkb:Glycophagy cargo receptor STBD1(gene name synonym)|uniprotkb:GENX-3414(orf name)|uniprotkb:Genethonin-1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_003934.1|ensembl:ENSG00000118804.9(gene)|ensembl:ENST00000237642.7(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030315""(T-tubule)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061723""(glycophagy)|go:""GO:0061753""(substrate localization to autophagosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:2001069""(glycogen binding)|go:""GO:2001070""(starch binding)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR034838|mint:O95210|rcsb pdb:8X8A|rcsb pdb:8X8K|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|panther:PTHR15048(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:nCP8UCnge2HywBnBiNfBW1GLJ0U9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q8TAA9	intact:EBI-10726177	intact:EBI-682393|uniprotkb:Q86WG8|uniprotkb:Q8N559|uniprotkb:Q5T1D3|uniprotkb:Q5T1D4|ensembl:ENSP00000310800.3|ensembl:ENSP00000347672.2|ensembl:ENSP00000358522.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:vang1_human(display_long)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Strabismus 2(gene name synonym)|uniprotkb:Loop-tail protein 2 homolog(gene name synonym)|uniprotkb:VANGL1(gene name)|psi-mi:VANGL1(display_short)|uniprotkb:STB2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:3027""|ensembl:ENSG00000173218.15(gene)|ensembl:ENST00000310260.7(transcript)|ensembl:ENST00000355485.7(transcript)|ensembl:ENST00000369509.1(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0043473""(pigmentation)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0120197""(mucociliary clearance)|interpro:IPR009539(Strabismus)|mint:Q8TAA9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001165882.1|refseq:NP_001165883.1|refseq:NP_620409.1|panther:PTHR20886(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:TRLqwMf+W5eZcgW8gT5S1zM9VzU9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q15907	intact:EBI-10726177	intact:EBI-722234|uniprotkb:Q2YDT2|uniprotkb:Q8NI07|uniprotkb:B2R7I4|uniprotkb:D6W671|uniprotkb:A5YM50|uniprotkb:Q5U0I1|uniprotkb:Q6FHR0|uniprotkb:Q6FI42|uniprotkb:B4DMK0|ensembl:ENSP00000333547.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:rb11b_human(display_long)|uniprotkb:GTP-binding protein YPT3(gene name synonym)|uniprotkb:RAB11B(gene name)|psi-mi:RAB11B(display_short)|uniprotkb:YPT3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_004209.2|ensembl:ENSG00000185236.12(gene)|ensembl:ENST00000328024.11(transcript)|go:""GO:0001881""(receptor recycling)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0019003""(GDP binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031489""(myosin V binding)|go:""GO:0032402""(melanosome transport)|go:""GO:0032456""(endocytic recycling)|go:""GO:0033572""(transferrin transport)|go:""GO:0035773""(insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0044070""(regulation of monoatomic anion transport)|go:""GO:0045054""(constitutive secretory pathway)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071468""(cellular response to acidic pH)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:2000008""(regulation of protein localization to cell surface)|go:""GO:2001135""(regulation of endocytic recycling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050209|mint:Q15907|rcsb pdb:2F9L|rcsb pdb:2F9M|rcsb pdb:4OJK|reactome:R-HSA-8854214|reactome:R-HSA-8873719|dip:DIP-50898N|panther:PTHR47979(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:+fsu7NPmd5fgoe0TE67IcISlscA9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9UBX3	intact:EBI-10726177	intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|ensembl:ENSG00000183048.12(gene)|ensembl:ENST00000350690.10(transcript)|go:""GO:0005310""(dicarboxylic acid transmembrane transporter activity)|go:""GO:0005315""(phosphate transmembrane transporter activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006835""(dicarboxylic acid transport)|go:""GO:0006869""(lipid transport)|go:""GO:0015116""(sulfate transmembrane transporter activity)|go:""GO:0015117""(thiosulfate transmembrane transporter activity)|go:""GO:0015131""(oxaloacetate transmembrane transporter activity)|go:""GO:0015140""(malate transmembrane transporter activity)|go:""GO:0015141""(succinate transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015709""(thiosulfate transport)|go:""GO:0015729""(oxaloacetate transport)|go:""GO:0035435""(phosphate ion transmembrane transport)|go:""GO:0046166""(glyceraldehyde-3-phosphate biosynthetic process)|go:""GO:0070221""(""sulfide oxidation, using sulfide:quinone oxidoreductase"")|go:""GO:0071422""(succinate transmembrane transport)|go:""GO:0071423""(malate transmembrane transport)|go:""GO:1902358""(sulfate transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|interpro:IPR050391|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643|panther:PTHR45618(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q96AP4	intact:EBI-10726177	intact:EBI-744706|uniprotkb:Q5TD92|uniprotkb:Q6PJH7|uniprotkb:Q96NV6|ensembl:ENSP00000357565.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:zup1_human(display_long)|uniprotkb:ZUP1(gene name)|psi-mi:ZUP1(display_short)|uniprotkb:C6orf113(gene name synonym)|uniprotkb:Lys-63-specific deubiquitinase ZUFSP(gene name synonym)|uniprotkb:ZUFSP(gene name synonym)|uniprotkb:Zinc finger with UFM1-specific peptidase domain protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_659499.2|refseq:XP_011533867.1|ensembl:ENSG00000153975.10(gene)|ensembl:ENST00000368576.8(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0046872""(metal ion binding)|interpro:IPR012462(Peptidase C78, ubiquitin fold modifier-specific peptidase 1 and 2)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR050688|mint:Q96AP4|rcsb pdb:6EI1|rcsb pdb:6FGE|panther:PTHR24403(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:GSe4doWK2dhUjZ+9YEwKuwecimM9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P80723	intact:EBI-10726177	intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281.3|ensembl:ENSP00000482066.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788.9(gene)|ensembl:ENST00000322611.4(transcript)|ensembl:ENST00000616743.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0007356""(thorax and anterior abdomen determination)|go:""GO:0008406""(gonad development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016605""(PML body)|go:""GO:0016607""(nuclear speck)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030054""(cell junction)|go:""GO:0030426""(growth cone)|go:""GO:0031982""(vesicle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0060231""(mesenchymal to epithelial transition)|go:""GO:0060421""(positive regulation of heart growth)|go:""GO:0060539""(diaphragm development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072075""(metanephric mesenchyme development)|go:""GO:0072112""(podocyte differentiation)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:2001076""(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034|panther:PTHR23212(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:X+L20HKimV3J+vLnQljg+x78+e09606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q96EY1	intact:EBI-10726177	intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375.4|ensembl:ENSP00000477570.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|ensembl:ENSG00000103423.14(gene)|ensembl:ENSG00000276726.4(gene)|ensembl:ENST00000262375.11(transcript)|ensembl:ENST00000612103.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0005133""(type II interferon receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006264""(mitochondrial DNA replication)|go:""GO:0006457""(protein folding)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006924""(activation-induced cell death of T cells)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009408""(response to heat)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030695""(GTPase regulator activity)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034341""(response to type II interferon)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0060336""(negative regulation of type II interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071340""(skeletal muscle acetylcholine-gated channel clustering)|go:""GO:0090398""(cellular senescence)|go:""GO:0106137""(IkappaB kinase complex binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR051938|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|rcsb pdb:7X89|dip:DIP-33870N|panther:PTHR44145(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9H2H9	intact:EBI-10726177	intact:EBI-9978441|uniprotkb:Q8NC61|uniprotkb:Q8NCF8|uniprotkb:Q96JX2|uniprotkb:Q9H2Q2|ensembl:ENSP00000381634.4|ensembl:ENSP00000398142.1|ensembl:ENSP00000447853.1|ensembl:ENSP00000449607.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:s38a1_human(display_long)|uniprotkb:SLC38A1(gene name)|psi-mi:SLC38A1(display_short)|uniprotkb:ATA1(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:SAT1(gene name synonym)|uniprotkb:SNAT1(gene name synonym)|uniprotkb:Amino acid transporter A1(gene name synonym)|uniprotkb:N-system amino acid transporter 2(gene name synonym)|uniprotkb:Solute carrier family 38 member 1(gene name synonym)|uniprotkb:System A amino acid transporter 1(gene name synonym)|uniprotkb:System N amino acid transporter 1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001070952.1|refseq:NP_001265316.1|refseq:NP_001265317.1|refseq:NP_001265318.1|refseq:NP_109599.3|ensembl:ENSG00000111371.16(gene)|ensembl:ENST00000398637.10(transcript)|ensembl:ENST00000439706.5(transcript)|ensembl:ENST00000546893.5(transcript)|ensembl:ENST00000549049.5(transcript)|go:""GO:0001504""(neurotransmitter uptake)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005283""(""amino acid:sodium symporter activity"")|go:""GO:0005295""(""neutral L-amino acid:sodium symporter activity"")|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0006865""(amino acid transport)|go:""GO:0006868""(glutamine transport)|go:""GO:0007565""(female pregnancy)|go:""GO:0009449""(gamma-aminobutyric acid biosynthetic process)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015175""(neutral L-amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015186""(L-glutamine transmembrane transporter activity)|go:""GO:0015375""(""glycine:sodium symporter activity"")|go:""GO:0015655""(""alanine:sodium symporter activity"")|go:""GO:0015804""(neutral amino acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030424""(axon)|go:""GO:0032228""(regulation of synaptic transmission, GABAergic)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043090""(amino acid import)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098591""(external side of apical plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901036""(positive regulation of L-glutamine import across plasma membrane)|go:""GO:1902475""(L-alpha-amino acid transmembrane transport)|interpro:IPR013057(Amino acid transporter, transmembrane)|mint:Q9H2H9|reactome:R-HSA-210455|reactome:R-HSA-352230|panther:PTHR22950(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:bywv401DbQBHRZvcPc8o8mp8nfE9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:O95881	intact:EBI-10726177	intact:EBI-2564581|uniprotkb:B3KQS0|uniprotkb:Q5T1T4|uniprotkb:Q96H50|ensembl:ENSP00000360688.4|ensembl:ENSP00000520430.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:txd12_human(display_long)|uniprotkb:TXNDC12(gene name)|psi-mi:TXNDC12(display_short)|uniprotkb:TLP19(gene name synonym)|uniprotkb:Thioredoxin-like protein p19(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 19(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 18(gene name synonym)|uniprotkb:hTLP19(gene name synonym)|uniprotkb:UNQ713/PRO1376(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_056997.1|ensembl:ENSG00000117862.14(gene)|ensembl:ENST00000371626.9(transcript)|ensembl:ENST00000715260.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0019153""(""protein-disulfide reductase (glutathione) activity"")|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR037462|interpro:IPR051099|mint:O95881|rcsb pdb:1SEN|rcsb pdb:2K8V|panther:PTHR15337(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:lgsrfn2RsfqJlKY0WWgUnvmMImM9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9NPH2	intact:EBI-10726177	intact:EBI-720563|intact:EBI-1050340|uniprotkb:Q7Z525|uniprotkb:Q9BT65|uniprotkb:Q9H2Y2|uniprotkb:Q9NSU0|uniprotkb:Q9NVW7|uniprotkb:Q6NXT5|uniprotkb:B3KRT1|uniprotkb:G5E9U0|ensembl:ENSP00000337746.7	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:ino1_human(display_long)|uniprotkb:INO1(gene name synonym)|uniprotkb:ISYNA1(gene name)|psi-mi:ISYNA1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase A1(gene name synonym)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001164409.1|refseq:NP_057452.1|refseq:NP_001240318.1|ensembl:ENSG00000105655.19(gene)|ensembl:ENST00000338128.13(transcript)|go:""GO:0004512""(inositol-3-phosphate synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006021""(inositol biosynthetic process)|go:""GO:0008654""(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|mint:Q9NPH2|reactome:R-HSA-1855183|panther:PTHR11510(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:46Ryo/iaI6hmbkuetMsJSyrm3FU9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P06730	intact:EBI-10726177	intact:EBI-73440|uniprotkb:Q96E95|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298|ensembl:ENSP00000389624.2	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001124150.1|refseq:NP_001124151.1|refseq:NP_001317946.1|refseq:NP_001959.1|panther:PTHR11960(orthology-group)|dip:DIP-22N|ensembl:ENST00000280892.10|ensembl:ENSP00000280892.6|ensembl:ENSP00000389624.2|ensembl:ENST00000505992.1|ensembl:ENSP00000425561.1|ensembl:ENSG00000151247.13(gene)|ensembl:ENST00000450253.7(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000339""(RNA cap binding)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000932""(P-body)|go:""GO:0001662""(behavioral fear response)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006413""(translational initiation)|go:""GO:0006417""(regulation of translation)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016442""(RISC complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0019899""(enzyme binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0031370""(eukaryotic initiation factor 4G binding)|go:""GO:0033391""(chromatoid body)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0098794""(postsynapse)|go:""GO:0098808""(mRNA cap binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099578""(regulation of translation at postsynapse, modulating synaptic transmission)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR001040(""Eukaryotic translation initiation factor 4E (eIF-4E)"")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|rcsb pdb:5ZML|rcsb pdb:7D6Y|rcsb pdb:7D8B|rcsb pdb:7EZW|rcsb pdb:7F07|rcsb pdb:7MEU|rcsb pdb:7XTP|rcsb pdb:8SX4|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q96AG4	intact:EBI-10726177	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|uniprotkb:B2RE83|ensembl:ENSP00000225972.7	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_060979.2|ensembl:ENSG00000108829.10(gene)|ensembl:ENST00000225972.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045296""(cadherin binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050216|mint:Q96AG4|panther:PTHR45752(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P61619	intact:EBI-10726177	intact:EBI-358919|uniprotkb:Q5JPF8|uniprotkb:P38378|uniprotkb:P57726|uniprotkb:Q8N3U3|uniprotkb:Q8NC71|uniprotkb:Q9BU16|uniprotkb:Q9Y2R3|uniprotkb:Q8N0Z4|ensembl:ENSP00000243253.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:s61a1_human(display_long)|uniprotkb:SEC61A1(gene name)|psi-mi:SEC61A1(display_short)|uniprotkb:SEC61A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_037468.1|ensembl:ENSG00000058262.11(gene)|ensembl:ENST00000243253.8(transcript)|go:""GO:0005048""(signal sequence binding)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005784""(Sec61 translocon complex)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006613""(cotranslational protein targeting to membrane)|go:""GO:0006614""(SRP-dependent cotranslational protein targeting to membrane)|go:""GO:0006616""(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0031204""(post-translational protein targeting to membrane, translocation)|go:""GO:0039019""(pronephric nephron development)|go:""GO:0043022""(ribosome binding)|go:""GO:0045047""(protein targeting to ER)|go:""GO:0045048""(protein insertion into ER membrane)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|mint:P61619|rcsb pdb:6W6L|rcsb pdb:8B6L|rcsb pdb:8DNV|rcsb pdb:8DNW|rcsb pdb:8DNX|rcsb pdb:8DNY|rcsb pdb:8DNZ|rcsb pdb:8DO0|rcsb pdb:8DO1|rcsb pdb:8DO2|rcsb pdb:8DO3|reactome:R-HSA-1236974|reactome:R-HSA-1799339|panther:PTHR10906(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:C+EzS02H/FYMX2nyfksXpRMs8G09606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9BQ39	intact:EBI-10726177	intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_076950.1|ensembl:ENSG00000107625.14(gene)|ensembl:ENST00000373585.8(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|interpro:IPR050079|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1|panther:PTHR47958(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P84157	intact:EBI-10726177	intact:EBI-5660715|uniprotkb:Q0P5W3|ensembl:ENSP00000348050.2	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:mxra7_human(display_long)|uniprotkb:MXRA7(gene name)|psi-mi:MXRA7(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001008528.1|refseq:NP_001008529.1|refseq:NP_940932.2|ensembl:ENSG00000182534.14(gene)|ensembl:ENST00000355797.7(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0016020""(membrane)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR026622|mint:P84157|panther:PTHR21845(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:5D8yzaF60a+81r61M5IhmtNhiNM9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q5JTV8	intact:EBI-10726177	intact:EBI-2559665|ensembl:ENSP00000476687.1|uniprotkb:Q9H8Y6|uniprotkb:Q8IZ65|uniprotkb:Q5JTV6|uniprotkb:B0QZ57|uniprotkb:Q9Y3X5|uniprotkb:Q9HAJ1|uniprotkb:Q9NV52|uniprotkb:A8K630|intact:EBI-40264785|uniprotkb:A0A0A0MSK5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:toip1_human(display_long)|uniprotkb:TOR1AIP1(gene name)|psi-mi:TOR1AIP1(display_short)|uniprotkb:Lamin-associated protein 1B(gene name synonym)|uniprotkb:LAP1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000143337.19(gene)|ensembl:ENST00000606911.7(transcript)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0051117""(ATPase binding)|go:""GO:0071763""(nuclear membrane organization)|go:""GO:0090435""(protein localization to nuclear envelope)|interpro:IPR008662(Lamina-associated polypeptide 1C)|interpro:IPR038599|interpro:IPR046753|interpro:IPR046754|mint:Q5JTV8|rcsb pdb:4TVS|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_001254507.1|refseq:NP_056417.2|dip:DIP-56692N|efo:""Orphanet:424261""|panther:PTHR18843(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:qFH5HTm3fcIwmGL486H8IqZHG489606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q8WUY9	intact:EBI-10726177	intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|uniprotkb:B4DUT4|ensembl:ENSP00000265036.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499.13(gene)|ensembl:ENST00000265036.10(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0016477""(cell migration)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0035556""(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|mint:Q8WUY9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|panther:PTHR16206(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P02545	intact:EBI-10726177	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292.6|ensembl:ENSP00000357283.4|ensembl:ENSP00000502256.1|ensembl:ENSP00000506771.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:154""|efo:""Orphanet:157973""|efo:""Orphanet:1662""|efo:""Orphanet:168796""|efo:""Orphanet:2229""|efo:""Orphanet:2348""|efo:""Orphanet:280365""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:300751""|efo:""Orphanet:363618""|efo:""Orphanet:54260""|efo:""Orphanet:740""|efo:""Orphanet:79084""|efo:""Orphanet:79474""|efo:""Orphanet:90153""|efo:""Orphanet:98853""|efo:""Orphanet:98855""|efo:""Orphanet:98856""|efo:""Orphanet:675396""|ensembl:ENSG00000160789.25(gene)|ensembl:ENST00000361308.9(transcript)|ensembl:ENST00000368300.9(transcript)|ensembl:ENST00000675939.1(transcript)|ensembl:ENST00000683032.1(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005882""(intermediate filament)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0007517""(muscle organ development)|go:""GO:0008104""(protein localization)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030951""(establishment or maintenance of microtubule cytoskeleton polarity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072201""(negative regulation of mesenchymal cell proliferation)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1900180""(regulation of protein localization to nucleus)|go:""GO:1903243""(negative regulation of cardiac muscle hypertrophy in response to stress)|go:""GO:1990683""(DNA double-strand break attachment to nuclear envelope)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|rcsb pdb:7CRG|rcsb pdb:7D9N|rcsb pdb:7WZZ|rcsb pdb:7X1B|rcsb pdb:7X5D|rcsb pdb:7YVD|rcsb pdb:7Z21|rcsb pdb:8I33|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|dip:DIP-32948N|dip:DIP-58162N|panther:PTHR45721(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P22314	intact:EBI-10726177	intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413.6|ensembl:ENSP00000366568.4	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:1145""|efo:""Orphanet:596753""|ensembl:ENSG00000130985.17(gene)|ensembl:ENST00000335972.11(transcript)|ensembl:ENST00000377351.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004839""(ubiquitin activating enzyme activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|interpro:IPR045886|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|rcsb pdb:7PYV|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|panther:PTHR10953(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P09234	intact:EBI-10726177	intact:EBI-766589|uniprotkb:Q5TAL3|ensembl:ENSP00000244520.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:ru1c_human(display_long)|uniprotkb:SNRPC(gene name)|psi-mi:SNRPC(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_003084.1|ensembl:ENSG00000124562.10(gene)|ensembl:ENST00000244520.10(transcript)|go:""GO:0000243""(commitment complex)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0000395""(mRNA 5'-splice site recognition)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005685""(U1 snRNP)|go:""GO:0008270""(zinc ion binding)|go:""GO:0015030""(Cajal body)|go:""GO:0030627""(pre-mRNA 5'-splice site binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0071004""(U2-type prespliceosome)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013085(Zinc finger, U1-C type)|interpro:IPR017340(U1 small nuclear ribonucleoprotein C)|interpro:IPR036236|mint:P09234|rcsb pdb:2VRD|rcsb pdb:3CW1|rcsb pdb:4PJO|rcsb pdb:6ELD|rcsb pdb:6QX9|rcsb pdb:7VPX|reactome:R-HSA-72163|dip:DIP-34235N|panther:PTHR31148(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:igW6pKnj1LJmvvs7PIWx03ip6Is9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:O15260	intact:EBI-10726177	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|uniprotkb:B7Z6A4|ensembl:ENSP00000361057.3|ensembl:ENSP00000486049.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_149351.1|refseq:NP_001267718.1|refseq:NP_001267721.1|ensembl:ENSG00000148248.14(gene)|ensembl:ENSG00000280951.3(gene)|ensembl:ENST00000371989.8(transcript)|ensembl:ENST00000629578.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0010638""(positive regulation of organelle organization)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032368""(regulation of lipid transport)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:0097020""(COPII receptor activity)|go:""GO:0140353""(lipid export from cell)|interpro:IPR002995(Surfeit locus 4)|interpro:IPR045214|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|panther:PTHR23427(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P46977	intact:EBI-10726177	intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472.3|ensembl:ENSP00000436962.1|ensembl:ENSP00000497336.1|uniprotkb:B4DJ24|uniprotkb:E9PNQ1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:370921""|ensembl:ENSG00000134910.14(gene)|ensembl:ENST00000392708.9(transcript)|ensembl:ENST00000529196.5(transcript)|ensembl:ENST00000649491.1(transcript)|go:""GO:0004579""(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0043686""(co-translational protein modification)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0046872""(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|interpro:IPR048307|interpro:IPR054479|mint:P46977|rcsb pdb:6S7O|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_001265432.1|refseq:NP_001265433.1|refseq:NP_689926.1|refseq:XP_011541109.1|panther:PTHR13872(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q5BKZ1	intact:EBI-10726177	intact:EBI-2560158|ensembl:ENSP00000340796.4|uniprotkb:Q6NSA2|uniprotkb:B4DLN0|uniprotkb:Q7Z638|uniprotkb:Q7Z6C2|uniprotkb:Q5VW97|uniprotkb:Q5VW96|uniprotkb:Q5VW94|uniprotkb:Q5VW93|uniprotkb:A8MYX1|uniprotkb:B4E179	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:zn326_human(display_long)|uniprotkb:ZNF326(gene name)|psi-mi:ZNF326(display_short)|uniprotkb:ZIRD(gene name synonym)|uniprotkb:Zinc finger protein 326(gene name synonym)|uniprotkb:Zinc finger protein interacting with mRNPs and DBC1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_892020.1|refseq:NP_892021.1|ensembl:ENSG00000162664.17(gene)|ensembl:ENST00000340281.9(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016363""(nuclear matrix)|go:""GO:0032784""(regulation of DNA-templated transcription elongation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0044609""(DBIRD complex)|go:""GO:0046872""(metal ion binding)|interpro:IPR007071(""A-kinase anchoring protein 95 (AKAP95)"")|interpro:IPR034736|mint:Q5BKZ1|refseq:XP_011539592.1|refseq:XP_005270836.1|refseq:NP_001307114.1|refseq:NP_861446.2|panther:PTHR12190(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:y4ZeI0cWMpNA2nQN/hDk6Zn7XRA9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q96S66	intact:EBI-10726177	intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|intact:EBI-40264131|ensembl:ENSP00000349456.2|ensembl:ENSP00000358986.3|ensembl:ENSP00000502251.1|ensembl:ENSP00000502457.1|ensembl:ENSP00000502648.1|ensembl:ENSP00000502836.1|ensembl:ENSP00000508473.1|ensembl:ENSP00000508563.1|ensembl:ENSP00000508607.1|ensembl:ENSP00000508816.1|ensembl:ENSP00000508884.1|ensembl:ENSP00000508952.1|ensembl:ENSP00000508982.1|ensembl:ENSP00000509013.1|ensembl:ENSP00000509036.1|ensembl:ENSP00000509218.1|ensembl:ENSP00000509330.1|ensembl:ENSP00000509420.1|ensembl:ENSP00000509451.1|ensembl:ENSP00000509533.1|ensembl:ENSP00000509544.1|ensembl:ENSP00000509584.1|ensembl:ENSP00000509782.1|ensembl:ENSP00000509936.1|ensembl:ENSP00000509960.1|ensembl:ENSP00000509990.1|ensembl:ENSP00000510067.1|ensembl:ENSP00000510137.1|ensembl:ENSP00000510142.1|ensembl:ENSP00000510291.1|ensembl:ENSP00000510352.1|ensembl:ENSP00000510582.1|ensembl:ENSP00000510602.1|ensembl:ENSP00000510666.1|ensembl:ENSP00000510675.1|ensembl:ENSP00000510715.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:clcc1_human(display_long)|uniprotkb:ER anion channel 1(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein(gene name synonym)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940.17(gene)|ensembl:ENST00000356970.6(transcript)|ensembl:ENST00000369969.7(transcript)|ensembl:ENST00000674849.1(transcript)|ensembl:ENST00000675508.1(transcript)|ensembl:ENST00000675654.1(transcript)|ensembl:ENST00000675956.1(transcript)|ensembl:ENST00000685014.1(transcript)|ensembl:ENST00000685104.1(transcript)|ensembl:ENST00000685497.1(transcript)|ensembl:ENST00000685540.1(transcript)|ensembl:ENST00000686078.1(transcript)|ensembl:ENST00000686776.1(transcript)|ensembl:ENST00000686821.1(transcript)|ensembl:ENST00000687328.1(transcript)|ensembl:ENST00000687449.1(transcript)|ensembl:ENST00000687591.1(transcript)|ensembl:ENST00000687865.1(transcript)|ensembl:ENST00000688285.1(transcript)|ensembl:ENST00000688778.1(transcript)|ensembl:ENST00000689189.1(transcript)|ensembl:ENST00000689351.1(transcript)|ensembl:ENST00000689359.1(transcript)|ensembl:ENST00000689991.1(transcript)|ensembl:ENST00000690509.1(transcript)|ensembl:ENST00000690756.1(transcript)|ensembl:ENST00000690781.1(transcript)|ensembl:ENST00000690874.1(transcript)|ensembl:ENST00000691513.1(transcript)|ensembl:ENST00000691556.1(transcript)|ensembl:ENST00000691731.1(transcript)|ensembl:ENST00000692404.1(transcript)|ensembl:ENST00000692511.1(transcript)|ensembl:ENST00000692795.1(transcript)|ensembl:ENST00000693089.1(transcript)|ensembl:ENST00000693336.1(transcript)|ensembl:ENST00000693673.1(transcript)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0034707""(chloride channel complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|interpro:IPR009231(Mid-1-related chloride channel)|mint:Q96S66|panther:PTHR34093(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:O75694	intact:EBI-10726177	intact:EBI-1050769|uniprotkb:Q9UBE9|uniprotkb:Q9UFL5|intact:EBI-28983292|ensembl:ENSP00000231498.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:nu155_human(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0791(gene name synonym)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"ensembl:ENSG00000113569.17(gene)|ensembl:ENST00000231498.8(transcript)|go:""GO:0000972""(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0016020""(membrane)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035196""(miRNA processing)|go:""GO:0036228""(protein localization to nuclear inner membrane)|go:""GO:0044611""(nuclear pore inner ring)|go:""GO:0086014""(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|interpro:IPR042538|mint:O75694|rcsb pdb:5A9Q|rcsb pdb:5IJN|rcsb pdb:5IJO|rcsb pdb:7EYE|rcsb pdb:7EYF|rcsb pdb:7EYQ|rcsb pdb:7PER|rcsb pdb:7R1Y|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9705671|refseq:NP_004289.1|refseq:NP_705618.1|efo:""Orphanet:334""|panther:PTHR10350(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:k6LjWvJdqtT78G4Wu12rJX/2WHo9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P04181	intact:EBI-10726177	intact:EBI-721662|uniprotkb:Q68CS0|uniprotkb:Q16068|uniprotkb:Q16069|uniprotkb:Q9UD03|intact:EBI-1237002|uniprotkb:Q6IAV9|uniprotkb:D3DRF0|ensembl:ENSP00000357838.5	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:oat_human(display_long)|uniprotkb:Ornithine--oxo-acid aminotransferase(gene name synonym)|uniprotkb:OAT(gene name)|psi-mi:OAT(display_short)|uniprotkb:Ornithine delta-aminotransferase(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:414""|ensembl:ENSG00000065154.12(gene)|ensembl:ENST00000368845.6(transcript)|go:""GO:0004587""(ornithine aminotransferase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0007601""(visual perception)|go:""GO:0010121""(arginine catabolic process to proline via ornithine)|go:""GO:0019544""(arginine catabolic process to glutamate)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR010164(Ornithine aminotransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR049704|interpro:IPR050103|mint:P04181|rcsb pdb:1GBN|rcsb pdb:1OAT|rcsb pdb:2BYJ|rcsb pdb:2BYL|rcsb pdb:2CAN|rcsb pdb:2OAT|rcsb pdb:5VWO|rcsb pdb:6HX7|rcsb pdb:6OIA|rcsb pdb:6V8C|rcsb pdb:6V8D|rcsb pdb:7JX9|rcsb pdb:7LK0|rcsb pdb:7LK1|rcsb pdb:7LNM|rcsb pdb:7LOM|rcsb pdb:7LON|rcsb pdb:7T9Z|rcsb pdb:7TA0|rcsb pdb:7TA1|rcsb pdb:7TED|rcsb pdb:7TEV|rcsb pdb:7TFP|rcsb pdb:8EZ1|rcsb pdb:8V9M|reactome:R-HSA-8964539|refseq:NP_000265.1|refseq:NP_001165285.1|refseq:NP_001309894.1|refseq:NP_001309895.1|refseq:NP_001309896.1|refseq:NP_001309897.1|refseq:NP_001309898.1|refseq:NP_001309899.1|refseq:NP_001309900.1|panther:PTHR11986(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:j+e5fOgz5Yv7lLp2NV8Uq+eR6909606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q9Y383	intact:EBI-10726177	intact:EBI-352851|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500|ensembl:ENSP00000347005.4	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|ensembl:ENSG00000146963.18(gene)|ensembl:ENST00000354926.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005685""(U1 snRNP)|go:""GO:0006376""(mRNA splice site recognition)|go:""GO:0016607""(nuclear speck)|go:""GO:0019899""(enzyme binding)|go:""GO:0071004""(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|dip:DIP-32513N|panther:PTHR12375(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:P61586	intact:EBI-10726177	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NG92	uniprotkb:Q8TBA6	intact:EBI-10726177	intact:EBI-11278147|uniprotkb:O95287|uniprotkb:Q03962|uniprotkb:Q2TS49|uniprotkb:Q9UQQ7|uniprotkb:C9JRU1|ensembl:ENSP00000163416.2	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:goga5_human(display_long)|uniprotkb:GOLGA5(gene name)|psi-mi:GOLGA5(display_short)|uniprotkb:Cell proliferation-inducing gene 31 protein(gene name synonym)|uniprotkb:Golgin-84(gene name synonym)|uniprotkb:Protein Ret-II(gene name synonym)|uniprotkb:RET-fused gene 5 protein(gene name synonym)|uniprotkb:RETII(gene name synonym)|uniprotkb:RFG5(gene name synonym)|uniprotkb:PIG31(orf name)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055968|imex:IM-29147-5	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:146""|ensembl:ENSG00000066455.13(gene)|ensembl:ENST00000163416.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000301""(retrograde transport, vesicle recycling within Golgi)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0007030""(Golgi organization)|go:""GO:0016020""(membrane)|go:""GO:0030133""(transport vesicle)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031985""(Golgi cisterna)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048193""(Golgi vesicle transport)|interpro:IPR019177|mint:Q8TBA6|reactome:R-HSA-6811438|refseq:NP_005104.3|refseq:XP_011535722.1|panther:PTHR13815(orthology-group)"	-	-	-	figure legend:ST2|comment:The interactor LOC101060252 wasn't inserted because doesn't have a UNIPROT Identifier.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:PtiO2qhE4u4CFxYqL+bqph4lmT09606	intact-crc:127611B3C7709562|rigid:FgFLs8L/Yqc0RtoGQ6zq6IaqU30	false	tandem tag:n-n	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P33176	intact:EBI-27055528	intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004512.1|ensembl:ENSG00000170759.11(gene)|ensembl:ENST00000302418.5(transcript)|go:""GO:0003777""(microtubule motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007028""(cytoplasm organization)|go:""GO:0007411""(axon guidance)|go:""GO:0008017""(microtubule binding)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031982""(vesicle)|go:""GO:0032230""(positive regulation of synaptic transmission, GABAergic)|go:""GO:0032418""(lysosome localization)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0035617""(stress granule disassembly)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042802""(identical protein binding)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0051642""(centrosome localization)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072383""(plus-end-directed vesicle transport along microtubule)|go:""GO:0098971""(anterograde dendritic transport of neurotransmitter receptor complex)|go:""GO:0098987""(regulation of modification of synapse structure, modulating synaptic transmission)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0160040""(mitocytosis)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990048""(anterograde neuronal dense core vesicle transport)|go:""GO:1990049""(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|rcsb pdb:7RIK|rcsb pdb:8IXA|rcsb pdb:8IXB|rcsb pdb:8IXD|rcsb pdb:8IXE|rcsb pdb:8IXF|rcsb pdb:8IXG|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-9725370|reactome:R-HSA-983189|dip:DIP-29244N|panther:PTHR24115(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y2J2	intact:EBI-27055528	intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158.2|uniprotkb:B7Z4I5|uniprotkb:F5GX05	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397.18(gene)|ensembl:ENST00000341928.7(transcript)|go:""GO:0002175""(protein localization to paranode region of axon)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006915""(apoptotic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0030054""(cell junction)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0030913""(paranodal junction assembly)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0033270""(paranode region of axon)|go:""GO:0043217""(myelin maintenance)|go:""GO:0044224""(juxtaparanode region of axon)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0071205""(protein localization to juxtaparanode region of axon)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098696""(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0106006""(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N|panther:PTHR23280(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O14654	intact:EBI-27055528	intact:EBI-356594|ensembl:ENSP00000505547.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.42	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_003595.1|ensembl:ENSG00000133124.12(gene)|ensembl:ENST00000564206.2(transcript)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|mint:O14654|reactome:R-HSA-2428928|panther:PTHR10614(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P42166	intact:EBI-27055528	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_003267.1|ensembl:ENSG00000120802.15(gene)|ensembl:ENST00000266732.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0045296""(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|interpro:IPR051656|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F|rcsb pdb:8FN7|rcsb pdb:8FND|rcsb pdb:8FNG|rcsb pdb:8FNH|rcsb pdb:8FNJ|rcsb pdb:8FNL|rcsb pdb:8FNM|rcsb pdb:8FNN|rcsb pdb:8FNO|rcsb pdb:8FNP|rcsb pdb:8FNQ|panther:PTHR12019(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y2U8	intact:EBI-27055528	intact:EBI-2561428|uniprotkb:Q9NT47|uniprotkb:Q9NYA5|ensembl:ENSP00000308369.2|intact:EBI-40264392	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:man1_human(display_long)|uniprotkb:MAN1(gene name synonym)|uniprotkb:LEM domain-containing protein 3(gene name synonym)|uniprotkb:LEMD3(gene name)|psi-mi:LEMD3(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000174106.3(gene)|ensembl:ENST00000308330.3(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0016020""(membrane)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032926""(negative regulation of activin receptor signaling pathway)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018996|interpro:IPR034394|interpro:IPR035979|interpro:IPR041885|interpro:IPR052277|mint:Q9Y2U8|rcsb pdb:2CH0|rcsb pdb:5ZOJ|rcsb pdb:5ZOK|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001161086.1|refseq:NP_055134.2|efo:""Orphanet:166119""|efo:""Orphanet:1879""|efo:""Orphanet:94063""|panther:PTHR48036(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:8AILzxAZLbxCAzlJ7oPg9WybOmY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P11171	intact:EBI-27055528	intact:EBI-1050906|uniprotkb:P11176|uniprotkb:Q14245|uniprotkb:Q5TB35|uniprotkb:Q5VXN8|uniprotkb:Q8IXV9|uniprotkb:Q9Y578|uniprotkb:Q9Y579|uniprotkb:B1ALH8|uniprotkb:B1ALH9|uniprotkb:D3DPM9|uniprotkb:D3DPN0|ensembl:ENSP00000345259.4|ensembl:ENSP00000362904.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:epb41_human(display_long)|uniprotkb:Band 4.1(gene name synonym)|uniprotkb:EPB4.1(gene name synonym)|uniprotkb:4.1R(gene name synonym)|uniprotkb:EPB41(gene name)|psi-mi:EPB41(display_short)|uniprotkb:E41P(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"dip:DIP-17032N|ensembl:ENSG00000159023.23(gene)|ensembl:ENST00000343067.9(transcript)|ensembl:ENST00000373798.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005545""(1-phosphatidylinositol binding)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0014731""(spectrin-associated cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030507""(spectrin binding)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045171""(intercellular bridge)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051301""(cell division)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0072686""(mitotic spindle)|go:""GO:1904478""(regulation of intestinal absorption)|go:""GO:1904778""(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR021187|interpro:IPR029071|interpro:IPR035963|mint:P11171|rcsb pdb:1GG3|rcsb pdb:2RQ1|rcsb pdb:3QIJ|reactome:R-HSA-6794361|refseq:NP_001159477.1|refseq:NP_001159478.1|refseq:NP_004428.1|refseq:NP_976217.1|refseq:XP_005245818.1|refseq:XP_005245821.1|refseq:XP_016856078.1|efo:""Orphanet:288""|panther:PTHR23280(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:ZCaM+kjScfGP23wRkFRwVyxOyvk9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P55196	intact:EBI-27055528	intact:EBI-365875|uniprotkb:O75089|uniprotkb:Q5TIG6|uniprotkb:O75087|uniprotkb:O75088|uniprotkb:Q9NSN7|uniprotkb:Q9NU92|uniprotkb:Q5TIG7|uniprotkb:Q59FP0|ensembl:ENSP00000404595.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:afad_human(display_long)|uniprotkb:AFDN(gene name)|psi-mi:AFDN(display_short)|uniprotkb:AF6(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 6 protein(gene name synonym)|uniprotkb:Afadin adherens junction formation factor(gene name synonym)|uniprotkb:MLLT4(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:XP_005267053.1|rcsb pdb:5A6C|rcsb pdb:7QCR|refseq:NP_001035089.1|refseq:NP_001193937.1|refseq:NP_001278893.1|reactome:R-HSA-418990|ensembl:ENSG00000130396.22(gene)|ensembl:ENST00000447894.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016607""(nuclear speck)|go:""GO:0022409""(positive regulation of cell-cell adhesion)|go:""GO:0030054""(cell junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045296""(cadherin binding)|go:""GO:0046930""(pore complex)|go:""GO:0046931""(pore complex assembly)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0061951""(establishment of protein localization to plasma membrane)|go:""GO:0070160""(tight junction)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0090557""(establishment of endothelial intestinal barrier)|go:""GO:2000049""(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR028842|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977|mint:P55196|rcsb pdb:1T2M|rcsb pdb:1XZ9|rcsb pdb:2AIN|rcsb pdb:2EXG|panther:PTHR10398(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:x7kK5K1+wAFZFdVopvQ/l496J5U9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q07866	intact:EBI-27055528	intact:EBI-721019|uniprotkb:F8VTM4|uniprotkb:Q7RTQ3|uniprotkb:Q86V77|uniprotkb:Q86V78|uniprotkb:Q86V79|uniprotkb:Q7RTM2|uniprotkb:Q7RTM3|uniprotkb:Q7RTM5|uniprotkb:Q7RTP9|uniprotkb:Q7RTQ5|uniprotkb:Q7RTQ6|uniprotkb:Q86SF5|uniprotkb:Q86TF5|uniprotkb:Q86V74|uniprotkb:Q86V75|uniprotkb:Q86V76|uniprotkb:Q96H62|uniprotkb:A6NF62|ensembl:ENSP00000341154.6|intact:EBI-28976313	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:klc1_human(display_long)|uniprotkb:KLC1(gene name)|psi-mi:KLC1(display_short)|uniprotkb:KLC(gene name synonym)|uniprotkb:KNS2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001123579.1|refseq:NP_005543.2|refseq:NP_891553.2|ensembl:ENSG00000126214.22(gene)|ensembl:ENST00000348520.10(transcript)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0030426""(growth cone)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035617""(stress granule disassembly)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q07866|rcsb pdb:3NF1|rcsb pdb:5OJ8|rcsb pdb:7AI4|rcsb pdb:7AIE|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-9725370|reactome:R-HSA-983189|dip:DIP-40371N|panther:PTHR45783(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:T7SJbB/PScRqj74O/NH4q1KU0YM9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O43491	intact:EBI-27055528	intact:EBI-1052044|uniprotkb:Q5T4F0|uniprotkb:B4DHI8|uniprotkb:Q68DV2|uniprotkb:E9PPD9|ensembl:ENSP00000338481.3|ensembl:ENSP00000357110.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:e41l2_human(display_long)|uniprotkb:Generally expressed protein 4.1(gene name synonym)|uniprotkb:EPB41L2(gene name)|psi-mi:EPB41L2(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001422.1|refseq:NP_001129026.1|refseq:NP_001129027.1|refseq:NP_001239589.1|refseq:XP_011533832.1|refseq:XP_011533836.1|refseq:XP_016865844.1|refseq:XP_016865848.1|refseq:XP_016865849.1|refseq:XP_016865850.1|refseq:XP_016865851.1|dip:DIP-17034N|ensembl:ENSG00000079819.20(gene)|ensembl:ENST00000337057.8(transcript)|ensembl:ENST00000368128.6(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0008091""(spectrin)|go:""GO:0030054""(cell junction)|go:""GO:0030507""(spectrin binding)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0042731""(PH domain binding)|go:""GO:0051301""(cell division)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904778""(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|mint:O43491|reactome:R-HSA-6794361|panther:PTHR23280(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:QvhY6g+bBqTBR8oHl/php27Wb7Y9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9H0B6	intact:EBI-27055528	intact:EBI-726994|uniprotkb:Q9H9C8|uniprotkb:Q9HA20|uniprotkb:B2RDY4|uniprotkb:A8MXL7|ensembl:ENSP00000314837.5|ensembl:ENSP00000377631.2|ensembl:ENSP00000399403.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:klc2_human(display_long)|uniprotkb:KLC2(gene name)|psi-mi:KLC2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000174996.12(gene)|ensembl:ENST00000316924.9(transcript)|ensembl:ENST00000394067.7(transcript)|ensembl:ENST00000417856.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0016020""(membrane)|go:""GO:0016938""(kinesin I complex)|go:""GO:0019894""(kinesin binding)|go:""GO:0032418""(lysosome localization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045296""(cadherin binding)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q9H0B6|rcsb pdb:3CEQ|rcsb pdb:3EDT|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_001128246.1|refseq:NP_001128247.1|refseq:NP_001128248.1|refseq:NP_001305663.1|refseq:NP_073733.1|refseq:XP_005274240.1|efo:""Orphanet:320406""|dip:DIP-40381N|panther:PTHR45783(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:VjzT5tI182sjUbhjxC1bK9GSMHo9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q14739	intact:EBI-27055528	intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163.4|ensembl:ENSP00000339883.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	"psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:""3-beta-hydroxysterol Delta (14)-reductase""(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:1426""|efo:""Orphanet:448267""|efo:""Orphanet:779""|dip:DIP-5987N|ensembl:ENSG00000143815.15(gene)|ensembl:ENST00000272163.9(transcript)|ensembl:ENST00000338179.6(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0030223""(neutrophil differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0050613""(Delta14-sterol reductase activity)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0070087""(chromo shadow domain binding)|go:""GO:0070402""(NADPH binding)|go:""GO:0140463""(chromatin-protein adaptor activity)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|panther:PTHR21257(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9UHN6	intact:EBI-27055528	intact:EBI-2876905|uniprotkb:B2RTQ6|uniprotkb:Q8NBP6|uniprotkb:Q5T841|uniprotkb:Q5T840|uniprotkb:Q9P2D5|uniprotkb:Q5T839|uniprotkb:Q5T838|uniprotkb:A6H8W9|ensembl:ENSP00000366243.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ceip2_human(display_long)|uniprotkb:CEMIP2(gene name)|psi-mi:CEMIP2(display_short)|uniprotkb:KIAA1412(gene name synonym)|uniprotkb:TMEM2(gene name synonym)|uniprotkb:Transmembrane protein 2(gene name synonym)|uniprotkb:Cell migration-inducing hyaluronidase 2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001129292.1|refseq:NP_037522.1|ensembl:ENSG00000135048.14(gene)|ensembl:ENST00000377044.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903670""(regulation of sprouting angiogenesis)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR019316|interpro:IPR039473|interpro:IPR039477|interpro:IPR052252|mint:Q9UHN6|rcsb pdb:8C6I|refseq:XP_005251926.1|panther:PTHR15535(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:LVdpEH7Df1biSXHseli56Y9l9XQ9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O60282	intact:EBI-27055528	intact:EBI-717170|uniprotkb:O95079|uniprotkb:Q2YDC5|ensembl:ENSP00000393379.1|ensembl:ENSP00000503013.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:kif5c_human(display_long)|uniprotkb:Kinesin-1(gene name synonym)|uniprotkb:Kinesin heavy chain neuron-specific 2(gene name synonym)|uniprotkb:KIF5C(gene name)|psi-mi:KIF5C(display_short)|uniprotkb:KIAA0531(gene name synonym)|uniprotkb:NKHC2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004513.1|refseq:XP_016859551.1|refseq:XP_011509459.1|ensembl:ENSG00000168280.18(gene)|ensembl:ENST00000435030.6(transcript)|ensembl:ENST00000677891.1(transcript)|go:""GO:0003777""(microtubule motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0006996""(organelle organization)|go:""GO:0007411""(axon guidance)|go:""GO:0008017""(microtubule binding)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034190""(apolipoprotein receptor binding)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044295""(axonal growth cone)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0051028""(mRNA transport)|go:""GO:0098964""(anterograde dendritic transport of messenger ribonucleoprotein complex)|go:""GO:0098971""(anterograde dendritic transport of neurotransmitter receptor complex)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:0150034""(distal axon)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:O60282|reactome:R-HSA-264876|panther:PTHR24115(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:4TqyBBhm1/nyaCSyz66oisPiwpA9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O15498	intact:EBI-27055528	intact:EBI-4402903|uniprotkb:Q53F01|uniprotkb:Q6FGU9|uniprotkb:Q6IB15|uniprotkb:B4DR94|ensembl:ENSP00000223369.2|ensembl:ENSP00000504623.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:ykt6_human(display_long)|uniprotkb:YKT6(gene name)|psi-mi:YKT6(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_006546.1|refseq:XP_016867171.1|ensembl:ENSG00000106636.9(gene)|ensembl:ENST00000223369.3(transcript)|ensembl:ENST00000679020.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006903""(vesicle targeting)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0030133""(transport vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045296""(cadherin binding)|go:""GO:0097440""(apical dendrite)|go:""GO:0097441""(basal dendrite)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR045848|mint:O15498|rcsb pdb:6J74|rcsb pdb:6J7F|rcsb pdb:6J7X|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9013423|panther:PTHR45806(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:pkTOoQ9XXEVYHKNvqOMCU6x4nZg9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9UEY8	intact:EBI-27055528	intact:EBI-2838698|uniprotkb:Q9UEY7|uniprotkb:O43243|uniprotkb:Q92773|uniprotkb:Q5VU09|uniprotkb:D3DRA8|ensembl:ENSP00000348381.4|intact:EBI-28975834	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:addg_human(display_long)|uniprotkb:ADD3(gene name)|psi-mi:ADD3(display_short)|uniprotkb:ADDL(gene name synonym)|uniprotkb:Adducin-like protein 70(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000148700.15(gene)|ensembl:ENST00000356080.9(transcript)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005938""(cell cortex)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051495""(positive regulation of cytoskeleton organization)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|interpro:IPR051017|mint:Q9UEY8|reactome:R-HSA-5223345|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_001112.2|refseq:NP_001307520.1|refseq:NP_001307521.1|refseq:NP_001307522.1|refseq:NP_001307523.1|refseq:NP_058432.1|refseq:NP_063968.1|efo:""Orphanet:210141""|panther:PTHR10672(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:10ZAHAI90VaVf/xUxFcNVX5cIts9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q7Z2W4	intact:EBI-27055528	intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_064504.2|refseq:NP_078901.3|dip:DIP-37896N|ensembl:ENSG00000105939.14(gene)|ensembl:ENST00000242351.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0009615""(response to virus)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0061014""(positive regulation of mRNA catabolic process)|go:""GO:1900246""(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|interpro:IPR051712|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|rcsb pdb:7KZH|rcsb pdb:7TGQ|reactome:R-HSA-6802952|panther:PTHR45740(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:O15173	intact:EBI-27055528	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425.4|ensembl:ENSP00000429301.2	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_006311.2|ensembl:ENSG00000164040.18(gene)|ensembl:ENST00000296425.10(transcript)|ensembl:ENST00000520121.6(transcript)|go:""GO:0003707""(nuclear steroid receptor activity)|go:""GO:0005496""(steroid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0012505""(endomembrane system)|go:""GO:0015232""(heme transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0060612""(adipose tissue development)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|interpro:IPR050577|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9707616|panther:PTHR10281(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9Y6M7	intact:EBI-27055528	intact:EBI-1044546|uniprotkb:O60350|uniprotkb:Q6AHZ9|uniprotkb:Q9HC88|uniprotkb:Q9UIB9|uniprotkb:A6NIA8|uniprotkb:B2CI53|uniprotkb:B5M451|uniprotkb:B5M452|uniprotkb:B5M453|uniprotkb:B6DY52|uniprotkb:B6DY53|uniprotkb:C9JST9|uniprotkb:B5M449|uniprotkb:D3K174|uniprotkb:D3K175|intact:EBI-10982200|intact:EBI-11577841|ensembl:ENSP00000295736.5	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	"psi-mi:s4a7_human(display_long)|uniprotkb:Sodium bicarbonate cotransporter 2(gene name synonym)|uniprotkb:Sodium bicarbonate cotransporter 2b(gene name synonym)|uniprotkb:Solute carrier family 4 member 7(gene name synonym)|uniprotkb:SLC4A7(gene name)|psi-mi:SLC4A7(display_short)|uniprotkb:BT(gene name synonym)|uniprotkb:NBC2(gene name synonym)|uniprotkb:NBC2B(gene name synonym)|uniprotkb:NBC3(gene name synonym)|uniprotkb:SBC2(gene name synonym)|uniprotkb:SLC4A6(gene name synonym)|uniprotkb:NBCn1(gene name synonym)|uniprotkb:""Electroneutral Na/HCO(3) cotransporter""(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_003606.3|refseq:NP_001245308.1|refseq:NP_001245309.1|refseq:NP_001308032.1|refseq:NP_001308033.1|refseq:NP_001308034.1|refseq:NP_001308035.1|refseq:NP_001308036.1|refseq:NP_001308037.1|refseq:XP_016863017.1|refseq:XP_016863018.1|ensembl:ENSG00000033867.18(gene)|ensembl:ENST00000295736.9(transcript)|go:""GO:0005452""(""solute:inorganic anion antiporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006221""(pyrimidine nucleotide biosynthetic process)|go:""GO:0008509""(monoatomic anion transmembrane transporter activity)|go:""GO:0008510""(""sodium:bicarbonate symporter activity"")|go:""GO:0015701""(bicarbonate transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0032420""(stereocilium)|go:""GO:0051453""(regulation of intracellular pH)|go:""GO:0055085""(transmembrane transport)|go:""GO:0060117""(auditory receptor cell development)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0090383""(phagosome acidification)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|mint:Q9Y6M7|reactome:R-HSA-425381|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9035034|panther:PTHR11453(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:vsq90qG3qxPyZgkoyvS0MPamvOg9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P55011	intact:EBI-27055528	intact:EBI-2801449|uniprotkb:Q8WWH7|uniprotkb:Q8N713|ensembl:ENSP00000262461.2|intact:EBI-28983018	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	"psi-mi:s12a2_human(display_long)|uniprotkb:Na-K-2Cl cotransporter 1(gene name synonym)|uniprotkb:NKCC1(gene name synonym)|uniprotkb:Basolateral Na-K-Cl symporter(gene name synonym)|uniprotkb:SLC12A2(gene name)|psi-mi:SLC12A2(display_short)|uniprotkb:""Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2""(gene name synonym)"	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000064651.14(gene)|ensembl:ENST00000262461.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0006972""(hyperosmotic response)|go:""GO:0007214""(gamma-aminobutyric acid signaling pathway)|go:""GO:0008511""(""sodium:potassium:chloride symporter activity"")|go:""GO:0008519""(ammonium channel activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010818""(T cell chemotaxis)|go:""GO:0015079""(potassium ion transmembrane transporter activity)|go:""GO:0015377""(""chloride:monoatomic cation symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030321""(transepithelial chloride transport)|go:""GO:0030644""(intracellular chloride ion homeostasis)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031253""(cell projection membrane)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0035865""(cellular response to potassium ion)|go:""GO:0042995""(cell projection)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044297""(cell body)|go:""GO:0044298""(cell body membrane)|go:""GO:0045795""(positive regulation of cell volume)|go:""GO:0046873""(metal ion transmembrane transporter activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0055064""(chloride ion homeostasis)|go:""GO:0055075""(potassium ion homeostasis)|go:""GO:0055078""(sodium ion homeostasis)|go:""GO:0061044""(negative regulation of vascular wound healing)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070634""(transepithelial ammonium transport)|go:""GO:0071944""(cell periphery)|go:""GO:0072488""(ammonium transmembrane transport)|go:""GO:0098658""(inorganic anion import across plasma membrane)|go:""GO:0098659""(inorganic cation import across plasma membrane)|go:""GO:0098719""(sodium ion import across plasma membrane)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902476""(chloride transmembrane transport)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904450""(positive regulation of aspartate secretion)|go:""GO:1904464""(regulation of matrix metallopeptidase secretion)|go:""GO:1990573""(potassium ion import across plasma membrane)|go:""GO:1990869""(cellular response to chemokine)|interpro:IPR002443(Na-K-Cl co-transporter)|interpro:IPR002444(Na-K-Cl co-transporter 1)|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004842(Na-K-Cl cotransporter superfamily)|interpro:IPR013612(Amino acid permease N-terminal)|interpro:IPR018491|mint:P55011|rcsb pdb:6PZT|rcsb pdb:7D10|rcsb pdb:7MXO|rcsb pdb:7N3N|rcsb pdb:7S1X|rcsb pdb:7S1Y|rcsb pdb:7S1Z|rcsb pdb:7SFL|rcsb pdb:7SMP|rcsb pdb:7ZGO|rcsb pdb:8STE|reactome:R-HSA-426117|refseq:NP_001037.1|dip:DIP-43979N|efo:""Orphanet:633021""|efo:""Orphanet:633024""|panther:PTHR11827(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:DJ/f5e8b/aBlnCcWYxYUa/mcoFY9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P35611	intact:EBI-27055528	intact:EBI-2809187|uniprotkb:Q16156|uniprotkb:Q14729|uniprotkb:A2A3P0|uniprotkb:Q13734|uniprotkb:Q9UJB6|uniprotkb:D3DVR3|uniprotkb:D3DVR4|uniprotkb:D3DVR5|uniprotkb:Q86XM2|ensembl:ENSP00000381197.1|uniprotkb:B4DI79|uniprotkb:A2A3N8|intact:EBI-28966889	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:adda_human(display_long)|uniprotkb:ADD1(gene name)|psi-mi:ADD1(display_short)|uniprotkb:ADDA(gene name synonym)|uniprotkb:Erythrocyte adducin subunit alpha(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001273574.1|refseq:XP_005247994.1|refseq:NP_001110.2|refseq:NP_054908.2|refseq:NP_054909.2|refseq:NP_789771.1|ensembl:ENSG00000087274.19(gene)|ensembl:ENST00000398129.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016604""(nuclear body)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030507""(spectrin binding)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:1903142""(positive regulation of establishment of endothelial barrier)|go:""GO:1903393""(positive regulation of adherens junction organization)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|interpro:IPR051017|mint:P35611|reactome:R-HSA-264870|reactome:R-HSA-381038|reactome:R-HSA-5223345|refseq:XP_016863193.1|refseq:XP_016863195.1|refseq:XP_016863196.1|refseq:XP_016863197.1|refseq:XP_016863198.1|refseq:XP_016863199.1|panther:PTHR10672(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:aXiCTFAzsmSxxV4OAr22SDyjAxI9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P28288	intact:EBI-27055528	intact:EBI-80992|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|ensembl:ENSP00000359233.4|uniprotkb:D3DT46	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001116146.1|refseq:NP_002849.1|ensembl:ENSG00000117528.14(gene)|ensembl:ENST00000370214.9(transcript)|go:""GO:0000038""(very long-chain fatty acid metabolic process)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0007031""(peroxisome organization)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0015910""(long-chain fatty acid import into peroxisome)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0042760""(very long-chain fatty acid catabolic process)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0047617""(fatty acyl-CoA hydrolase activity)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:1903512""(phytanic acid metabolic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR050835|mint:P28288|rcsb pdb:8Z0F|rcsb pdb:8Z9X|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798|panther:PTHR11384(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9H2G2	intact:EBI-27055528	intact:EBI-1022272|uniprotkb:O00211|uniprotkb:Q6P1Z4|uniprotkb:Q86WU7|uniprotkb:Q86WW1|uniprotkb:Q92603|uniprotkb:Q9NQL0|uniprotkb:Q9NQL1|uniprotkb:D3DRA0|uniprotkb:D3DRA1|ensembl:ENSP00000358770.3	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:slk_human(display_long)|uniprotkb:STE20-related serine/threonine-protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:CTCL tumor antigen se20-9(gene name synonym)|uniprotkb:SLK(gene name)|psi-mi:SLK(display_short)|uniprotkb:KIAA0204(gene name synonym)|uniprotkb:STK2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_055535.2|refseq:NP_001291672.1|ensembl:ENSG00000065613.15(gene)|ensembl:ENST00000369755.4(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|interpro:IPR051585|mint:Q9H2G2|rcsb pdb:2J51|rcsb pdb:2JFL|rcsb pdb:2JFM|rcsb pdb:2UV2|rcsb pdb:4USF|rcsb pdb:6HVD|rcsb pdb:8BEM|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|panther:PTHR48012(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:T9Ej6CkWUmqEmPLcptvF2/f1Q+09606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q8TAA9	intact:EBI-27055528	intact:EBI-682393|uniprotkb:Q86WG8|uniprotkb:Q8N559|uniprotkb:Q5T1D3|uniprotkb:Q5T1D4|ensembl:ENSP00000310800.3|ensembl:ENSP00000347672.2|ensembl:ENSP00000358522.1	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:vang1_human(display_long)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Strabismus 2(gene name synonym)|uniprotkb:Loop-tail protein 2 homolog(gene name synonym)|uniprotkb:VANGL1(gene name)|psi-mi:VANGL1(display_short)|uniprotkb:STB2(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:3027""|ensembl:ENSG00000173218.15(gene)|ensembl:ENST00000310260.7(transcript)|ensembl:ENST00000355485.7(transcript)|ensembl:ENST00000369509.1(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0043473""(pigmentation)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0120197""(mucociliary clearance)|interpro:IPR009539(Strabismus)|mint:Q8TAA9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001165882.1|refseq:NP_001165883.1|refseq:NP_620409.1|panther:PTHR20886(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:TRLqwMf+W5eZcgW8gT5S1zM9VzU9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q9BSJ8	intact:EBI-27055528	intact:EBI-355956|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548|ensembl:ENSP00000377612.5|intact:EBI-21360363	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001171725.1|refseq:NP_056107.1|ensembl:ENSG00000139641.13(gene)|ensembl:ENST00000394048.10(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0008429""(phosphatidylethanolamine binding)|go:""GO:0016020""(membrane)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:0120014""(phospholipid transfer activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|interpro:IPR051634|mint:Q9BSJ8|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9845576|dip:DIP-57197N|panther:PTHR45761(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:Q14126	intact:EBI-27055528	intact:EBI-2556545|uniprotkb:Q4KKU6|ensembl:ENSP00000261590.8	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:dsg2_human(display_long)|uniprotkb:CDHF5(gene name synonym)|uniprotkb:HDGC(gene name synonym)|uniprotkb:Cadherin family member 5(gene name synonym)|uniprotkb:DSG2(gene name)|psi-mi:DSG2(display_short)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"dip:DIP-46250N|efo:""Orphanet:154""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|ensembl:ENSG00000046604.15(gene)|ensembl:ENST00000261590.13(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0002934""(desmosome organization)|go:""GO:0003165""(Purkinje myocyte development)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0009986""(cell surface)|go:""GO:0014704""(intercalated disc)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0030054""(cell junction)|go:""GO:0030057""(desmosome)|go:""GO:0032570""(response to progesterone)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0086073""(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:""GO:0086083""(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR050971|mint:Q14126|rcsb pdb:2YQG|rcsb pdb:5ERD|rcsb pdb:5J5J|rcsb pdb:6QNT|rcsb pdb:6QNU|rcsb pdb:6SIT|rcsb pdb:7A7D|rcsb pdb:7AGF|rcsb pdb:7AGG|rcsb pdb:8QJX|rcsb pdb:8QJY|rcsb pdb:8QK3|reactome:R-HSA-351906|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:NP_001934.2|panther:PTHR24025(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:LCSf84WRgh5lTrze5IEzFaBeuEc9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3NF08	uniprotkb:P51798	intact:EBI-27055528	intact:EBI-4402346|uniprotkb:A6NEJ7|uniprotkb:A8K5T9|uniprotkb:Q9NYX5|uniprotkb:A8K7X1|uniprotkb:B3KPN3|uniprotkb:E9PDB9|ensembl:ENSP00000372193.4	psi-mi:a0a0h3nf08_salts(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:G1W50_04775(orf name)|uniprotkb:G1W53_06125(orf name)|uniprotkb:G1W54_06530(orf name)|uniprotkb:G1W56_02980(orf name)|uniprotkb:G1W63_08870(orf name)|uniprotkb:G1W64_02720(orf name)|uniprotkb:G1W86_05560(orf name)|uniprotkb:G1W87_02720(orf name)|uniprotkb:G1W89_02720(orf name)|uniprotkb:G1W92_02495(orf name)|uniprotkb:G1X03_08760(orf name)|uniprotkb:G1X04_16645(orf name)|uniprotkb:G1X09_02720(orf name)|uniprotkb:G1X10_06140(orf name)|uniprotkb:G1X13_02720(orf name)|uniprotkb:G1X17_02720(orf name)|uniprotkb:G1X23_06125(orf name)|uniprotkb:G1X29_02720(orf name)|uniprotkb:G1X32_06215(orf name)|uniprotkb:G1X38_06520(orf name)|uniprotkb:G1X42_02495(orf name)|uniprotkb:G1X47_17605(orf name)|uniprotkb:G1X49_08855(orf name)|uniprotkb:G1X51_02720(orf name)|uniprotkb:G1X52_02725(orf name)|uniprotkb:G1X66_06520(orf name)|uniprotkb:G1X68_03425(orf name)|uniprotkb:G1X69_02985(orf name)|uniprotkb:G1X71_02725(orf name)|uniprotkb:G1X76_06190(orf name)|uniprotkb:G1X80_06190(orf name)|uniprotkb:G1X84_06220(orf name)|uniprotkb:G1X85_06530(orf name)|uniprotkb:G1X86_03360(orf name)|uniprotkb:G1X94_06200(orf name)|uniprotkb:G1X96_03365(orf name)|uniprotkb:G1X99_02720(orf name)|uniprotkb:G1Y02_06220(orf name)|uniprotkb:SL1344_2763(locus name)	psi-mi:clcn7_human(display_long)|uniprotkb:CLCN7(gene name)|psi-mi:CLCN7(display_short)|uniprotkb:Chloride channel protein 7(gene name synonym)|uniprotkb:Chloride channel 7 alpha subunit(gene name synonym)	"psi-mi:""MI:1314""(proximity-dependent biotin identification)"	D'Costa et al. (2019)	imex:IM-29147|pubmed:31611645	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:2364""(proximity)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27055973|imex:IM-29147-29	intact-miscore:0.27	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|mint:A0A0H3NF08|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000103249.19(gene)|ensembl:ENST00000382745.9(transcript)|go:""GO:0005247""(voltage-gated chloride channel activity)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0015108""(chloride transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0016020""(membrane)|go:""GO:0030321""(transepithelial chloride transport)|go:""GO:0034707""(chloride channel complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002249(Chloride channel CLC-7)|interpro:IPR014743(Chloride channel, core)|interpro:IPR046342|interpro:IPR051280|mint:P51798|rcsb pdb:7BXU|rcsb pdb:7CQ5|rcsb pdb:7CQ6|rcsb pdb:7CQ7|rcsb pdb:7JM7|rcsb pdb:8HVT|reactome:R-HSA-2672351|refseq:NP_001107803.1|refseq:NP_001278.1|efo:""Orphanet:210110""|efo:""Orphanet:53""|efo:""Orphanet:667""|panther:PTHR11689(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293lp-In T-REx)|taxid:9606(Homo sapiens HEK293flp-in T-REX embryonic kidney cell)	-	2021/07/28	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE216597	rogid:ze820JsKN1GtxH/lcPnPWN78k1I9606	intact-crc:B4D67A34DC27405C|rigid:vmWcmu9eKxTCnuo3EWGwgDXvNmI	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q8NEN9	intact:EBI-27033185	intact:EBI-4289868|uniprotkb:Q86WE5|uniprotkb:Q9UFF1|uniprotkb:Q86WE0|ensembl:ENSP00000334642.5	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:pdzd8_human(display_long)|uniprotkb:PDZD8(gene name)|psi-mi:PDZD8(display_short)|uniprotkb:PDZK8(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-84/NY-SAR-104(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033211|imex:IM-29092-121	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_776152.1|mint:Q8NEN9|rcsb pdb:7F6J|ensembl:ENSG00000165650.12(gene)|ensembl:ENST00000334464.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0046872""(metal ion binding)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|interpro:IPR046349|panther:PTHR21519(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:J/uE/PwFeE+ZL58Qi2jAWaEf23s9606	intact-crc:7B0A2A5EDC8DD87F|rigid:7HbZyCgMAoUqFPS5nT3Xh8HD9RU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q16555	intact:EBI-27033185	intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|uniprotkb:A8K5H2|uniprotkb:B4DR31|ensembl:ENSP00000309539.5	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033211|imex:IM-29092-121	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000092964.18(gene)|ensembl:ENST00000311151.9(transcript)|go:""GO:0004157""(dihydropyrimidinase activity)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|go:""GO:0006897""(endocytosis)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0016812""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides"")|go:""GO:0030154""(cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR032466|interpro:IPR050378|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|rcsb pdb:7X68|rcsb pdb:8DNM|reactome:R-HSA-399956|reactome:R-HSA-437239|refseq:NP_001184222.1|refseq:NP_001231533.1|refseq:NP_001377.1|efo:""Orphanet:178469""|panther:PTHR11647(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606	intact-crc:7B0A2A5EDC8DD87F|rigid:7HbZyCgMAoUqFPS5nT3Xh8HD9RU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q9C0I1	intact:EBI-27033185	intact:EBI-2829520|uniprotkb:Q6PFW3|uniprotkb:Q9NX27|uniprotkb:Q96QU2|uniprotkb:Q69YJ4|ensembl:ENSP00000371577.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:mtmrc_human(display_long)|uniprotkb:MTMR12(gene name)|psi-mi:MTMR12(display_short)|uniprotkb:KIAA1682(gene name synonym)|uniprotkb:PIP3AP(gene name synonym)|uniprotkb:Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit(gene name synonym)|uniprotkb:Inactive phosphatidylinositol 3-phosphatase 12(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033211|imex:IM-29092-121	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001035536.1|refseq:NP_001281272.1|refseq:NP_001281273.1|ensembl:ENSG00000150712.11(gene)|ensembl:ENST00000382142.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0030017""(sarcomere)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022587|interpro:IPR029021|interpro:IPR030564|interpro:IPR030576|mint:Q9C0I1|reactome:R-HSA-1660516|panther:PTHR10807(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2024/11/14	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:qd9tvo8NLF+Y6jVs9YnqCeyR6hw9606	intact-crc:7B0A2A5EDC8DD87F|rigid:7HbZyCgMAoUqFPS5nT3Xh8HD9RU	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q7KZI7	intact:EBI-27033185	intact:EBI-516560|uniprotkb:Q15449|uniprotkb:Q15524|uniprotkb:Q5XGA3|uniprotkb:Q68A18|uniprotkb:Q96HB3|uniprotkb:Q96RG0|ensembl:ENSP00000385751.2	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:mark2_human(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001034558.2|refseq:NP_001156768.1|refseq:NP_001156769.1|refseq:NP_004945.4|refseq:NP_059672.2|ensembl:ENSG00000072518.23(gene)|ensembl:ENST00000402010.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0001764""(neuron migration)|go:""GO:0003723""(RNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008289""(lipid binding)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0030425""(dendrite)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0050770""(regulation of axonogenesis)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051646""(mitochondrion localization)|go:""GO:0061564""(axon development)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071963""(establishment or maintenance of cell polarity regulating cell shape)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097427""(microtubule bundle)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1904526""(regulation of microtubule binding)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:Q7KZI7|rcsb pdb:3IEC|rcsb pdb:5EAK|rcsb pdb:5KZ7|rcsb pdb:5KZ8|rcsb pdb:8TXY|dip:DIP-31321N|panther:PTHR24346(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:yfUqSCu4bgkncBd6hRRg5pKkArc9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q9H0B6	intact:EBI-27033185	intact:EBI-726994|uniprotkb:Q9H9C8|uniprotkb:Q9HA20|uniprotkb:B2RDY4|uniprotkb:A8MXL7|ensembl:ENSP00000314837.5|ensembl:ENSP00000377631.2|ensembl:ENSP00000399403.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:klc2_human(display_long)|uniprotkb:KLC2(gene name)|psi-mi:KLC2(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000174996.12(gene)|ensembl:ENST00000316924.9(transcript)|ensembl:ENST00000394067.7(transcript)|ensembl:ENST00000417856.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0016020""(membrane)|go:""GO:0016938""(kinesin I complex)|go:""GO:0019894""(kinesin binding)|go:""GO:0032418""(lysosome localization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045296""(cadherin binding)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q9H0B6|rcsb pdb:3CEQ|rcsb pdb:3EDT|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_001128246.1|refseq:NP_001128247.1|refseq:NP_001128248.1|refseq:NP_001305663.1|refseq:NP_073733.1|refseq:XP_005274240.1|efo:""Orphanet:320406""|dip:DIP-40381N|panther:PTHR45783(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:VjzT5tI182sjUbhjxC1bK9GSMHo9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q14997	intact:EBI-27033185	intact:EBI-1236916|uniprotkb:Q1XBG4|uniprotkb:Q1XBG5|uniprotkb:Q1XBG6|uniprotkb:Q2M1Z0|uniprotkb:Q6IPR2|uniprotkb:Q86XF8|ensembl:ENSP00000384211.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:psme4_human(display_long)|uniprotkb:PSME4(gene name)|psi-mi:PSME4(display_short)|uniprotkb:KIAA0077(gene name synonym)|uniprotkb:Proteasome activator PA200(gene name synonym)|uniprotkb:BLM10(gene name synonym)|uniprotkb:Protein BLM10 homolog(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_055429.2|ensembl:ENSG00000068878.15(gene)|ensembl:ENST00000404125.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006974""(DNA damage response)|go:""GO:0010499""(proteasomal ubiquitin-independent protein catabolic process)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0016607""(nuclear speck)|go:""GO:0035092""(sperm DNA condensation)|go:""GO:0070577""(lysine-acetylated histone binding)|go:""GO:0070628""(proteasome binding)|go:""GO:1990111""(spermatoproteasome complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021843|interpro:IPR032430|interpro:IPR035309|mint:Q14997|rcsb pdb:6KWX|rcsb pdb:6KWY|rcsb pdb:6REY|rcsb pdb:7NAQ|rcsb pdb:8CVS|reactome:R-HSA-9907900|dip:DIP-38203N|panther:PTHR32170(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:wKVv+GwMVpoOZZS1eNP+rDe85tE9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q7Z3C6	intact:EBI-27033185	intact:EBI-727146|uniprotkb:Q6P0N7|uniprotkb:Q7Z317|uniprotkb:Q7Z320|uniprotkb:Q8NDK6|uniprotkb:Q8WU65|uniprotkb:Q9BVL5|uniprotkb:Q9H6L1|uniprotkb:Q9HAG7|uniprotkb:Q3ZAQ6|ensembl:ENSP00000355173.4|ensembl:ENSP00000379983.2|ensembl:ENSP00000386710.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:atg9a_human(display_long)|uniprotkb:APG9-like 1(gene name synonym)|uniprotkb:ATG9A(gene name)|psi-mi:ATG9A(display_short)|uniprotkb:APG9L1(gene name synonym)|uniprotkb:mATG9(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001070666.1|refseq:NP_076990.4|go:""GO:0000423""(mitophagy)|go:""GO:0005739""(mitochondrion)|ensembl:ENSG00000198925.12(gene)|ensembl:ENST00000361242.9(transcript)|ensembl:ENST00000396761.6(transcript)|ensembl:ENST00000409618.5(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0005768""(endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0016020""(membrane)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0034497""(protein localization to phagophore assembly site)|go:""GO:0034727""(piecemeal microautophagy of the nucleus)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061709""(reticulophagy)|go:""GO:0097300""(programmed necrotic cell death)|interpro:IPR007241(Autophagy protein 99)|mint:Q7Z3C6|rcsb pdb:6WQZ|rcsb pdb:6WR4|rcsb pdb:7JLO|rcsb pdb:7JLP|rcsb pdb:7JLQ|rcsb pdb:8KBZ|rcsb pdb:8KC3|rcsb pdb:8Y1L|reactome:R-HSA-1632852|reactome:R-HSA-5205685|panther:PTHR13038(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:arvq+TjXETr14g/FkOITnLfYVh89606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P61421	intact:EBI-27033185	intact:EBI-954063|uniprotkb:P12953|uniprotkb:Q02547|ensembl:ENSP00000290949.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:va0d1_human(display_long)|uniprotkb:Vacuolar proton pump subunit d 1(gene name synonym)|uniprotkb:V-ATPase AC39 subunit(gene name synonym)|uniprotkb:V-ATPase 40 kDa accessory protein(gene name synonym)|uniprotkb:32 kDa accessory protein(gene name synonym)|uniprotkb:ATP6V0D1(gene name)|psi-mi:ATP6V0D1(display_short)|uniprotkb:ATP6D(gene name synonym)|uniprotkb:VPATPD(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004682.2|dip:DIP-47435N|ensembl:ENSG00000159720.13(gene)|ensembl:ENST00000290949.8(transcript)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007034""(vacuolar transport)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0033181""(plasma membrane proton-transporting V-type ATPase complex)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0043679""(axon terminus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|mint:P61421|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|rcsb pdb:7UNF|reactome:R-HSA-1222556|reactome:R-HSA-381038|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-9857377|panther:PTHR11028(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:3a/yIxEF9LMwAZUR3npGQrw8xNo9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P53007	intact:EBI-27033185	intact:EBI-359163|uniprotkb:Q9BSK6|uniprotkb:A8K8E8|ensembl:ENSP00000215882.5	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:txtp_human(display_long)|uniprotkb:SLC25A1(gene name)|psi-mi:SLC25A1(display_short)|uniprotkb:SLC20A3(gene name synonym)|uniprotkb:Citrate transport protein(gene name synonym)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 1(gene name synonym)|uniprotkb:Mitochondrial citrate carrier(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:356978""|efo:""Orphanet:98914""|ensembl:ENSG00000100075.10(gene)|ensembl:ENST00000215882.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006843""(mitochondrial citrate transmembrane transport)|go:""GO:0015137""(citrate transmembrane transporter activity)|go:""GO:0015142""(tricarboxylic acid transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071913""(citrate secondary active transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|interpro:IPR049563|mint:P53007|reactome:R-HSA-428643|refseq:NP_005975.1|panther:PTHR45788(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:MB0RrMAQme4F8M4IivU1AqUxlgA9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q08AM6	intact:EBI-27033185	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776.5	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR16023(orthology-group)|efo:""Orphanet:3472""|efo:""Orphanet:497906""|ensembl:ENSG00000103043.15(gene)|ensembl:ENST00000261776.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0007165""(signal transduction)|go:""GO:0010008""(endosome membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070772""(PAS complex)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|refseq:NP_060522.3"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P61764	intact:EBI-27033185	intact:EBI-960169|uniprotkb:Q28208|uniprotkb:Q62759|uniprotkb:Q64320|uniprotkb:Q96TG8|uniprotkb:B1AM97|ensembl:ENSP00000362396.2|uniprotkb:Q68CM6	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:stxb1_human(display_long)|uniprotkb:STXBP1(gene name)|psi-mi:STXBP1(display_short)|uniprotkb:UNC18A(gene name synonym)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:N-Sec1(gene name synonym)|uniprotkb:p67(gene name synonym)|uniprotkb:MUNC18-1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:495818""|efo:""Orphanet:599373""|ensembl:ENSG00000136854.26(gene)|ensembl:ENST00000373299.5(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0002576""(platelet degranulation)|go:""GO:0003006""(developmental process involved in reproduction)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0007274""(neuromuscular synaptic transmission)|go:""GO:0007412""(axon target recognition)|go:""GO:0010807""(regulation of synaptic vesicle priming)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0016188""(synaptic vesicle maturation)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030141""(secretory granule)|go:""GO:0030424""(axon)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031630""(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0032229""(negative regulation of synaptic transmission, GABAergic)|go:""GO:0032355""(response to estradiol)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0035542""(regulation of SNARE complex assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043306""(positive regulation of mast cell degranulation)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045956""(positive regulation of calcium ion-dependent exocytosis)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0060292""(long-term synaptic depression)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098688""(parallel fiber to Purkinje cell synapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098831""(presynaptic active zone cytoplasmic component)|go:""GO:0098888""(extrinsic component of presynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0099525""(presynaptic dense core vesicle exocytosis)|go:""GO:0106022""(positive regulation of vesicle docking)|go:""GO:1903296""(positive regulation of glutamate secretion, neurotransmission)|go:""GO:2000367""(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:P61764|rcsb pdb:6L03|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-422356|reactome:R-HSA-6794361|reactome:R-HSA-888590|refseq:NP_001027392.1|refseq:NP_003156.1|panther:PTHR11679(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:yUYi89hDkfMdQ1BdH52swZQFCLk9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P33176	intact:EBI-27033185	intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078.4	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_004512.1|ensembl:ENSG00000170759.11(gene)|ensembl:ENST00000302418.5(transcript)|go:""GO:0003777""(microtubule motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007028""(cytoplasm organization)|go:""GO:0007411""(axon guidance)|go:""GO:0008017""(microtubule binding)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031982""(vesicle)|go:""GO:0032230""(positive regulation of synaptic transmission, GABAergic)|go:""GO:0032418""(lysosome localization)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0035617""(stress granule disassembly)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042802""(identical protein binding)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0051642""(centrosome localization)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072383""(plus-end-directed vesicle transport along microtubule)|go:""GO:0098971""(anterograde dendritic transport of neurotransmitter receptor complex)|go:""GO:0098987""(regulation of modification of synapse structure, modulating synaptic transmission)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0160040""(mitocytosis)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990048""(anterograde neuronal dense core vesicle transport)|go:""GO:1990049""(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|rcsb pdb:7RIK|rcsb pdb:8IXA|rcsb pdb:8IXB|rcsb pdb:8IXD|rcsb pdb:8IXE|rcsb pdb:8IXF|rcsb pdb:8IXG|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-9725370|reactome:R-HSA-983189|dip:DIP-29244N|panther:PTHR24115(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q07866	intact:EBI-27033185	intact:EBI-721019|uniprotkb:F8VTM4|uniprotkb:Q7RTQ3|uniprotkb:Q86V77|uniprotkb:Q86V78|uniprotkb:Q86V79|uniprotkb:Q7RTM2|uniprotkb:Q7RTM3|uniprotkb:Q7RTM5|uniprotkb:Q7RTP9|uniprotkb:Q7RTQ5|uniprotkb:Q7RTQ6|uniprotkb:Q86SF5|uniprotkb:Q86TF5|uniprotkb:Q86V74|uniprotkb:Q86V75|uniprotkb:Q86V76|uniprotkb:Q96H62|uniprotkb:A6NF62|ensembl:ENSP00000341154.6|intact:EBI-28976313	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:klc1_human(display_long)|uniprotkb:KLC1(gene name)|psi-mi:KLC1(display_short)|uniprotkb:KLC(gene name synonym)|uniprotkb:KNS2(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001123579.1|refseq:NP_005543.2|refseq:NP_891553.2|ensembl:ENSG00000126214.22(gene)|ensembl:ENST00000348520.10(transcript)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0030426""(growth cone)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035617""(stress granule disassembly)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q07866|rcsb pdb:3NF1|rcsb pdb:5OJ8|rcsb pdb:7AI4|rcsb pdb:7AIE|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-9725370|reactome:R-HSA-983189|dip:DIP-40371N|panther:PTHR45783(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:T7SJbB/PScRqj74O/NH4q1KU0YM9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q9NP58	intact:EBI-27033185	intact:EBI-2115230|uniprotkb:O75542|uniprotkb:Q49A66|uniprotkb:Q59GQ5|uniprotkb:Q6ZME6|uniprotkb:Q96ME8|uniprotkb:Q9HAQ6|uniprotkb:Q9HAQ7|ensembl:ENSP00000265316.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:abcb6_human(display_long)|uniprotkb:ABCB6(gene name)|psi-mi:ABCB6(display_short)|uniprotkb:MTABC3(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:UMAT(gene name synonym)|uniprotkb:Mitochondrial ABC transporter 3(gene name synonym)|uniprotkb:Ubiquitously-expressed mammalian ABC half transporter(gene name synonym)|uniprotkb:P-glycoprotein-related protein(gene name synonym)|uniprotkb:ABC-type heme transporter ABCB6(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR24221(orthology-group)|ensembl:ENSG00000115657.14(gene)|ensembl:ENST00000265316.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005740""(mitochondrial envelope)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006778""(porphyrin-containing compound metabolic process)|go:""GO:0006779""(porphyrin-containing compound biosynthetic process)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007420""(brain development)|go:""GO:0015439""(ABC-type heme transporter activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:0015886""(heme transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0020037""(heme binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033013""(tetrapyrrole metabolic process)|go:""GO:0033162""(melanosome membrane)|go:""GO:0035351""(heme transmembrane transport)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0042168""(heme metabolic process)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|go:""GO:0043588""(skin development)|go:""GO:0046906""(tetrapyrrole binding)|go:""GO:0055085""(transmembrane transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098849""(cellular detoxification of cadmium ion)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:1903232""(melanosome assembly)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032410|interpro:IPR036640|interpro:IPR039421|mint:Q9NP58|rcsb pdb:3NH6|rcsb pdb:3NH9|rcsb pdb:3NHA|rcsb pdb:3NHB|rcsb pdb:7D7N|rcsb pdb:7D7R|rcsb pdb:7DNY|rcsb pdb:7DNZ|rcsb pdb:7EKL|rcsb pdb:7EKM|rcsb pdb:8FWK|rcsb pdb:8K7B|rcsb pdb:8K7C|rcsb pdb:8YR3|rcsb pdb:8YR4|reactome:R-HSA-1369007|reactome:R-HSA-5683371|refseq:NP_005680.1|efo:""Orphanet:241""|efo:""Orphanet:90044""|efo:""Orphanet:98938""|efo:""Orphanet:98942""|efo:""Orphanet:98943""|efo:""Orphanet:98944""|efo:""Orphanet:98945""|efo:""Orphanet:98946""|efo:""Orphanet:98947"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:3Zyw4d16oU1oT0eiAcOds3s1ZVQ9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P55011	intact:EBI-27033185	intact:EBI-2801449|uniprotkb:Q8WWH7|uniprotkb:Q8N713|ensembl:ENSP00000262461.2|intact:EBI-28983018	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	"psi-mi:s12a2_human(display_long)|uniprotkb:Na-K-2Cl cotransporter 1(gene name synonym)|uniprotkb:NKCC1(gene name synonym)|uniprotkb:Basolateral Na-K-Cl symporter(gene name synonym)|uniprotkb:SLC12A2(gene name)|psi-mi:SLC12A2(display_short)|uniprotkb:""Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2""(gene name synonym)"	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000064651.14(gene)|ensembl:ENST00000262461.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0006972""(hyperosmotic response)|go:""GO:0007214""(gamma-aminobutyric acid signaling pathway)|go:""GO:0008511""(""sodium:potassium:chloride symporter activity"")|go:""GO:0008519""(ammonium channel activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0010818""(T cell chemotaxis)|go:""GO:0015079""(potassium ion transmembrane transporter activity)|go:""GO:0015377""(""chloride:monoatomic cation symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030321""(transepithelial chloride transport)|go:""GO:0030644""(intracellular chloride ion homeostasis)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031253""(cell projection membrane)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0035865""(cellular response to potassium ion)|go:""GO:0042995""(cell projection)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044297""(cell body)|go:""GO:0044298""(cell body membrane)|go:""GO:0045795""(positive regulation of cell volume)|go:""GO:0046873""(metal ion transmembrane transporter activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0055064""(chloride ion homeostasis)|go:""GO:0055075""(potassium ion homeostasis)|go:""GO:0055078""(sodium ion homeostasis)|go:""GO:0061044""(negative regulation of vascular wound healing)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070634""(transepithelial ammonium transport)|go:""GO:0071944""(cell periphery)|go:""GO:0072488""(ammonium transmembrane transport)|go:""GO:0098658""(inorganic anion import across plasma membrane)|go:""GO:0098659""(inorganic cation import across plasma membrane)|go:""GO:0098719""(sodium ion import across plasma membrane)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902476""(chloride transmembrane transport)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904450""(positive regulation of aspartate secretion)|go:""GO:1904464""(regulation of matrix metallopeptidase secretion)|go:""GO:1990573""(potassium ion import across plasma membrane)|go:""GO:1990869""(cellular response to chemokine)|interpro:IPR002443(Na-K-Cl co-transporter)|interpro:IPR002444(Na-K-Cl co-transporter 1)|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004842(Na-K-Cl cotransporter superfamily)|interpro:IPR013612(Amino acid permease N-terminal)|interpro:IPR018491|mint:P55011|rcsb pdb:6PZT|rcsb pdb:7D10|rcsb pdb:7MXO|rcsb pdb:7N3N|rcsb pdb:7S1X|rcsb pdb:7S1Y|rcsb pdb:7S1Z|rcsb pdb:7SFL|rcsb pdb:7SMP|rcsb pdb:7ZGO|rcsb pdb:8STE|reactome:R-HSA-426117|refseq:NP_001037.1|dip:DIP-43979N|efo:""Orphanet:633021""|efo:""Orphanet:633024""|panther:PTHR11827(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:DJ/f5e8b/aBlnCcWYxYUa/mcoFY9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q6P1M0	intact:EBI-27033185	intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000167114.13(gene)|ensembl:ENST00000300456.5(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0001579""(medium-chain fatty acid transport)|go:""GO:0001676""(long-chain fatty acid metabolic process)|go:""GO:0004467""(long-chain fatty acid-CoA ligase activity)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0007584""(response to nutrient)|go:""GO:0015245""(fatty acid transmembrane transporter activity)|go:""GO:0015908""(fatty acid transport)|go:""GO:0015909""(long-chain fatty acid transport)|go:""GO:0016020""(membrane)|go:""GO:0031526""(brush border membrane)|go:""GO:0031957""(very long-chain fatty acid-CoA ligase activity)|go:""GO:0042760""(very long-chain fatty acid catabolic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043588""(skin development)|go:""GO:0044381""(glucose import in response to insulin stimulus)|go:""GO:0044539""(long-chain fatty acid import into cell)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0047676""(arachidonate-CoA ligase activity)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0090433""(palmitoyl-CoA ligase activity)|go:""GO:0090434""(oleoyl-CoA ligase activity)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901480""(oleate transmembrane transporter activity)|go:""GO:1990379""(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR042099|interpro:IPR045851|mint:Q6P1M0|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:NP_005085.2|refseq:XP_016869711.1|efo:""Orphanet:88621""|panther:PTHR43107(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P61106	intact:EBI-27033185	intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946.4|ensembl:ENSP00000515613.1|ensembl:ENSP00000515614.1|intact:EBI-21352994	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_057406.2|ensembl:ENSG00000119396.12(gene)|ensembl:ENST00000373840.9(transcript)|ensembl:ENST00000703999.1(transcript)|ensembl:ENST00000704000.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001845""(phagolysosome assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005795""(Golgi stack)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019003""(GDP binding)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0031489""(myosin V binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0042175""(nuclear outer membrane-endoplasmic reticulum membrane network)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090382""(phagosome maturation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|interpro:IPR050209|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P33527	intact:EBI-27033185	intact:EBI-3911547|ensembl:ENSP00000382342.3|ensembl:ENSP00000483316.1|uniprotkb:O14819|uniprotkb:Q9UQ99|uniprotkb:P78419|uniprotkb:A3RJX2|uniprotkb:Q59GI9|uniprotkb:O43333|uniprotkb:Q9UQ97|uniprotkb:Q9UQA0|uniprotkb:C9JPJ4	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	"psi-mi:mrp1_human(display_long)|uniprotkb:ABCC1(gene name)|psi-mi:ABCC1(display_short)|uniprotkb:MRP(gene name synonym)|uniprotkb:MRP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 1(gene name synonym)|uniprotkb:""Leukotriene C(4) transporter""(gene name synonym)|uniprotkb:Glutathione-S-conjugate-translocating ATPase ABCC1(gene name synonym)"	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000103222.20(gene)|ensembl:ENSG00000278183.4(gene)|ensembl:ENST00000399410.8(transcript)|ensembl:ENST00000621144.4(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006691""(leukotriene metabolic process)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0008559""(ABC-type xenobiotic transporter activity)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0015420""(ABC-type vitamin B12 transporter activity)|go:""GO:0015431""(ABC-type glutathione S-conjugate transporter activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:0015889""(cobalamin transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030148""(sphingolipid biosynthetic process)|go:""GO:0034040""(ATPase-coupled lipid transmembrane transporter activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034634""(glutathione transmembrane transporter activity)|go:""GO:0034775""(glutathione transmembrane transport)|go:""GO:0042167""(heme catabolic process)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0042908""(xenobiotic transport)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|go:""GO:0043225""(ATPase-coupled inorganic anion transmembrane transporter activity)|go:""GO:0045332""(phospholipid translocation)|go:""GO:0046624""(sphingolipid transporter activity)|go:""GO:0046943""(carboxylic acid transmembrane transporter activity)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0055085""(transmembrane transport)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070633""(transepithelial transport)|go:""GO:0070729""(cyclic nucleotide transport)|go:""GO:0071716""(leukotriene transport)|go:""GO:0099039""(sphingolipid translocation)|go:""GO:0140115""(export across plasma membrane)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905039""(carboxylic acid transmembrane transport)|go:""GO:1990962""(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005292(""Multi drug resistance-associated protein (MRP)"")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR050173|mint:P33527|rcsb pdb:2CBZ|rcsb pdb:4C3Z|reactome:R-HSA-1660661|reactome:R-HSA-189483|reactome:R-HSA-2142691|reactome:R-HSA-382556|reactome:R-HSA-9707564|reactome:R-HSA-9753281|reactome:R-HSA-9758890|reactome:R-HSA-9818032|refseq:NP_004987.2|efo:""Orphanet:90635""|panther:PTHR24223(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:XGzXibUwQjwbAsg7ueuXS9YxUVc9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q8TCT9	intact:EBI-27033185	intact:EBI-347472|uniprotkb:Q540H8|uniprotkb:Q5JWP2|uniprotkb:Q5JWP3|uniprotkb:Q5JWP4|uniprotkb:Q5JWP5|uniprotkb:Q7Z4F2|uniprotkb:Q86Y35|uniprotkb:Q95H87|uniprotkb:Q9H110|uniprotkb:Q9H111|uniprotkb:Q15K36|uniprotkb:B2RAY5|uniprotkb:E1P5L3|ensembl:ENSP00000343032.5	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:hm13_human(display_long)|uniprotkb:HM13(gene name)|psi-mi:HM13(display_short)|uniprotkb:H13(gene name synonym)|uniprotkb:PSL3(gene name synonym)|uniprotkb:SPP(gene name synonym)|uniprotkb:Signal peptide peptidase(gene name synonym)|uniprotkb:Presenilin-like protein 3(gene name synonym)|uniprotkb:Intramembrane protease 1(gene name synonym)|uniprotkb:IMP1(gene name synonym)|uniprotkb:MSTP086(orf name)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_110416.1|refseq:NP_848695.1|refseq:NP_848696.1|refseq:NP_848697.1|panther:PTHR12174(orthology-group)|ensembl:ENSG00000101294.20(gene)|ensembl:ENST00000340852.9(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006465""(signal peptide processing)|go:""GO:0008233""(peptidase activity)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0033619""(membrane protein proteolysis)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0036513""(Derlin-1 retrotranslocation complex)|go:""GO:0042500""(aspartic endopeptidase activity, intramembrane cleaving)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:1904211""(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR007369(Peptidase A22B, signal peptide peptidase)|mint:Q8TCT9|reactome:R-HSA-9707587"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:DxNjJDcc+zomfXAj0TEaByKeNqc9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P05023	intact:EBI-27033185	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|ensembl:ENSP00000295598.5|intact:EBI-10963133	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"panther:PTHR43294(orthology-group)|ensembl:ENSG00000163399.16(gene)|ensembl:ENST00000295598.10(transcript)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0005391""(""P-type sodium:potassium-exchanging transporter activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0007231""(osmosensory signaling pathway)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016791""(phosphatase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030315""(T-tubule)|go:""GO:0030424""(axon)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031090""(organelle membrane)|go:""GO:0031402""(sodium ion binding)|go:""GO:0031947""(negative regulation of glucocorticoid biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0045823""(positive regulation of heart contraction)|go:""GO:0045989""(positive regulation of striated muscle contraction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060342""(photoreceptor inner segment membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086009""(membrane repolarization)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1902600""(proton transmembrane transport)|go:""GO:1903416""(response to glycoside)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990239""(steroid hormone binding)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|interpro:IPR050510|mint:P05023|rcsb pdb:7E1Z|rcsb pdb:7E20|rcsb pdb:7E21|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|efo:""Orphanet:521414""|efo:""Orphanet:564178"""	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q93050	intact:EBI-27033185	intact:EBI-2891238|uniprotkb:Q8N5G7|uniprotkb:Q9NSX0|intact:EBI-4324496|uniprotkb:B7Z3B7|ensembl:ENSP00000342951.3|ensembl:ENSP00000515539.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:vpp1_human(display_long)|uniprotkb:ATP6V0A1(gene name)|psi-mi:ATP6V0A1(display_short)|uniprotkb:ATP6N1(gene name synonym)|uniprotkb:ATP6N1A(gene name synonym)|uniprotkb:VPP1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"go:""GO:1902600""(proton transmembrane transport)|ensembl:ENSG00000033627.18(gene)|ensembl:ENST00000343619.9(transcript)|ensembl:ENST00000703901.1(transcript)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0042470""(melanosome)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051117""(ATPase binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|mint:Q93050|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:NP_001123492.1|refseq:NP_001123493.1|refseq:NP_005168.2|efo:""Orphanet:528084""|panther:PTHR11629(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:3htDhXCA9potj7i32HoA2j3Sfqw9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P05556	intact:EBI-27033185	intact:EBI-703066|intact:EBI-4289597|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5|ensembl:ENSP00000303351.3|ensembl:ENSP00000379350.2|ensembl:ENSP00000398029.2|ensembl:ENSP00000404546.3|ensembl:ENSP00000502882.1|ensembl:ENSP00000503546.1|ensembl:ENSP00000503916.1|ensembl:ENSP00000504205.1|ensembl:ENSP00000504444.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|ensembl:ENSG00000150093.20(gene)|ensembl:ENST00000302278.8(transcript)|ensembl:ENST00000396033.6(transcript)|ensembl:ENST00000417122.7(transcript)|ensembl:ENST00000437302.6(transcript)|ensembl:ENST00000677999.1(transcript)|ensembl:ENST00000678701.1(transcript)|ensembl:ENST00000678943.1(transcript)|ensembl:ENST00000678952.1(transcript)|dip:DIP-312N|ensembl:ENST00000678989.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001726""(ruffle)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002020""(protease binding)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006968""(cellular defense response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007517""(muscle organ development)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008305""(integrin complex)|go:""GO:0008354""(germ cell migration)|go:""GO:0008542""(visual learning)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010710""(regulation of collagen catabolic process)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0014704""(intercalated disc)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030175""(filopodium)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031623""(receptor internalization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0033631""(cell-cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034665""(integrin alpha1-beta1 complex)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0034667""(integrin alpha3-beta1 complex)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0034674""(integrin alpha5-beta1 complex)|go:""GO:0034675""(integrin alpha6-beta1 complex)|go:""GO:0034677""(integrin alpha7-beta1 complex)|go:""GO:0034678""(integrin alpha8-beta1 complex)|go:""GO:0034679""(integrin alpha9-beta1 complex)|go:""GO:0034680""(integrin alpha10-beta1 complex)|go:""GO:0034681""(integrin alpha11-beta1 complex)|go:""GO:0034682""(integrin alphav-beta1 complex)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043197""(dendritic spine)|go:""GO:0043235""(receptor complex)|go:""GO:0043236""(laminin binding)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045743""(positive regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048626""(myoblast fate specification)|go:""GO:0048675""(axon extension)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051951""(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0055037""(recycling endosome)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060912""(cardiac cell fate specification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097386""(glial cell projection)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150053""(cerebellar climbing fiber to Purkinje cell synapse)|go:""GO:0150103""(reactive gliosis)|go:""GO:1900748""(positive regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901979""(regulation of inward rectifier potassium channel activity)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905806""(regulation of synapse pruning)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|rcsb pdb:7CEB|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEC|rcsb pdb:7NWL|rcsb pdb:7NXD|rcsb pdb:8RPQ|rcsb pdb:9CKV|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9634597|reactome:R-HSA-9679191|reactome:R-HSA-9725554|reactome:R-HSA-9830674|reactome:R-HSA-9860927|panther:PTHR10082(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:O00767	intact:EBI-27033185	intact:EBI-2684237|uniprotkb:Q5W037|uniprotkb:B2R5U0|uniprotkb:Q96KF6|uniprotkb:Q53GR9|uniprotkb:Q9Y695|uniprotkb:Q9BS07|uniprotkb:Q16150|uniprotkb:Q6GSS4|uniprotkb:Q5W038|uniprotkb:D3DR68|ensembl:ENSP00000359380.2	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	"psi-mi:scd_human(display_long)|uniprotkb:""Delta(9)-desaturase""(gene name synonym)|uniprotkb:Fatty acid desaturase(gene name synonym)|uniprotkb:Acyl-CoA desaturase(gene name synonym)|uniprotkb:FADS5(gene name synonym)|uniprotkb:SCD1(gene name synonym)|uniprotkb:SCDOS(gene name synonym)|uniprotkb:SCD(gene name)|psi-mi:SCD(display_short)"	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_005054.3|ensembl:ENSG00000099194.6(gene)|ensembl:ENST00000370355.3(transcript)|go:""GO:0004768""(stearoyl-CoA 9-desaturase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006636""(unsaturated fatty acid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0032896""(palmitoyl-CoA 9-desaturase activity)|go:""GO:0070542""(response to fatty acid)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1903966""(monounsaturated fatty acid biosynthetic process)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|mint:O00767|rcsb pdb:4ZYO|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|reactome:R-HSA-9841922|panther:PTHR11351(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:GeF7PMgZb07js39m6ykSSmFuIUA9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P02786	intact:EBI-27033185	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224.4|ensembl:ENSP00000376197.3|ensembl:ENSP00000513646.1|ensembl:ENSP00000513654.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"efo:""Orphanet:476113""|ensembl:ENSG00000072274.14(gene)|ensembl:ENST00000360110.9(transcript)|ensembl:ENST00000392396.7(transcript)|ensembl:ENST00000698280.1(transcript)|ensembl:ENST00000698291.1(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004998""(transferrin receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010039""(response to iron ion)|go:""GO:0010042""(response to manganese ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010637""(negative regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033572""(transferrin transport)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0046688""(response to copper ion)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0072562""(blood microparticle)|go:""GO:0098944""(postsynaptic recycling endosome membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|interpro:IPR046450|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|rcsb pdb:7ZQS|rcsb pdb:8P0Z|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9725554|refseq:NP_001121620.1|refseq:NP_001300894.1|refseq:NP_001300895.1|refseq:NP_003225.2|dip:DIP-2736N|panther:PTHR10404(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q9UP95	intact:EBI-27033185	intact:EBI-7244836|uniprotkb:Q13953|uniprotkb:B7ZAV0|uniprotkb:O75893|uniprotkb:O60632|intact:MINT-1191426|uniprotkb:F5H0S9|uniprotkb:B4DZ82|uniprotkb:B4DF69|uniprotkb:Q96LD5|uniprotkb:F5H3C0|uniprotkb:F5H066|uniprotkb:B4DR04|intact:EBI-11577771|ensembl:ENSP00000318557.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:s12a4_human(display_long)|uniprotkb:SLC12A4(gene name)|psi-mi:SLC12A4(display_short)|uniprotkb:KCC1(gene name synonym)|uniprotkb:Electroneutral potassium-chloride cotransporter 1(gene name synonym)|uniprotkb:Erythroid K-Cl cotransporter 1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001139436.1|refseq:NP_001139433.1|refseq:NP_001139434.1|refseq:NP_005063.1|refseq:NP_001139435.1|ensembl:ENSG00000124067.17(gene)|ensembl:ENST00000316341.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0015379""(""potassium:chloride symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0045202""(synapse)|go:""GO:0055064""(chloride ion homeostasis)|go:""GO:0055075""(potassium ion homeostasis)|go:""GO:0071805""(potassium ion transmembrane transport)|go:""GO:1902476""(chloride transmembrane transport)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR000076(K-Cl co-transporter)|interpro:IPR000622(K-Cl Co-transporter, type 1)|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004842(Na-K-Cl cotransporter superfamily)|interpro:IPR018491|mint:Q9UP95|rcsb pdb:6KKR|rcsb pdb:6KKT|rcsb pdb:6KKU|rcsb pdb:7AIP|rcsb pdb:7AIQ|rcsb pdb:7AIR|rcsb pdb:7TTH|rcsb pdb:7TTI|reactome:R-HSA-426117|panther:PTHR11827(orthology-group)"	-	-	"comment:mint|comment:homomint|function:""\""Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity\"""""	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:wyweg+klinikkDDzNhNdIwomyDQ9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:Q13488	intact:EBI-27033185	intact:EBI-3914669|uniprotkb:Q8WVC5|uniprotkb:O75877|ensembl:ENSP00000265686.3	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:vpp3_human(display_long)|uniprotkb:TCIRG1(gene name)|psi-mi:TCIRG1(display_short)|uniprotkb:ATP6N1C(gene name synonym)|uniprotkb:ATP6V0A3(gene name synonym)|uniprotkb:Osteoclastic proton pump 116 kDa subunit(gene name synonym)|uniprotkb:T-cell immune regulator 1(gene name synonym)|uniprotkb:T-cell immune response cDNA7 protein(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000110719.11(gene)|ensembl:ENST00000265686.8(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0001503""(ossification)|go:""GO:0002158""(osteoclast proliferation)|go:""GO:0005634""(nucleus)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007039""(protein catabolic process in the vacuole)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010008""(endosome membrane)|go:""GO:0010155""(regulation of proton transport)|go:""GO:0010272""(response to silver ion)|go:""GO:0010467""(gene expression)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0016236""(macroautophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0021554""(optic nerve development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031529""(ruffle organization)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0033365""(protein localization to organelle)|go:""GO:0035709""(memory T cell activation)|go:""GO:0035711""(T-helper 1 cell activation)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0044691""(tooth eruption)|go:""GO:0045453""(bone resorption)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0045851""(pH reduction)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0051117""(ATPase binding)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|go:""GO:0070166""(enamel mineralization)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0090383""(phagosome acidification)|go:""GO:0097188""(dentin mineralization)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|mint:Q13488|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|refseq:NP_006010.2|refseq:NP_006044.1|refseq:XP_005273766.1|refseq:XP_011543028.1|efo:""Orphanet:1782""|efo:""Orphanet:210110""|efo:""Orphanet:486""|efo:""Orphanet:667""|panther:PTHR11629(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:WhJvt8AOkbC24bz4x4CxGyZcuow9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P29317	intact:EBI-27033185	intact:EBI-702104|uniprotkb:Q8N3Z2|ensembl:ENSP00000351209.5|uniprotkb:B5A968|intact:EBI-28989000	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:epha2_human(display_long)|uniprotkb:Tyrosine-protein kinase receptor ECK(gene name synonym)|uniprotkb:Epithelial cell kinase(gene name synonym)|uniprotkb:EPHA2(gene name)|psi-mi:EPHA2(display_short)|uniprotkb:ECK(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"ensembl:ENSG00000142627.13(gene)|ensembl:ENST00000358432.8(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0002043""(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008288""(boss receptor activity)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009986""(cell surface)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0014028""(notochord formation)|go:""GO:0016477""(cell migration)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019838""(growth factor binding)|go:""GO:0021915""(neural tube development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0043235""(receptor complex)|go:""GO:0043535""(regulation of blood vessel endothelial cell migration)|go:""GO:0045296""(cadherin binding)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0046058""(cAMP metabolic process)|go:""GO:0046849""(bone remodeling)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048320""(axial mesoderm formation)|go:""GO:0048870""(cell motility)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0060035""(notochord cell development)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0060444""(branching involved in mammary gland duct morphogenesis)|go:""GO:0070160""(tight junction)|go:""GO:0070309""(lens fiber cell morphogenesis)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070848""(response to growth factor)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1901491""(negative regulation of lymphangiogenesis)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1904238""(pericyte cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034263|interpro:IPR036116|interpro:IPR050449|mint:P29317|rcsb pdb:1MQB|rcsb pdb:2E8N|rcsb pdb:2K9Y|rcsb pdb:2KSO|rcsb pdb:2X10|rcsb pdb:2X11|rcsb pdb:3C8X|rcsb pdb:3CZU|rcsb pdb:3FL7|rcsb pdb:3HEI|rcsb pdb:3HPN|rcsb pdb:3KKA|rcsb pdb:3MBW|rcsb pdb:3MX0|rcsb pdb:3SKJ|rcsb pdb:4P2K|rcsb pdb:4PDO|rcsb pdb:4TRL|rcsb pdb:5EK7|rcsb pdb:5I9U|rcsb pdb:5I9V|rcsb pdb:5I9W|rcsb pdb:5I9X|rcsb pdb:5I9Y|rcsb pdb:5I9Z|rcsb pdb:5IA0|rcsb pdb:5IA1|rcsb pdb:5IA2|rcsb pdb:5IA3|rcsb pdb:5IA4|rcsb pdb:5IA5|rcsb pdb:5NJZ|rcsb pdb:5NK0|rcsb pdb:5NK1|rcsb pdb:5NK2|rcsb pdb:5NK3|rcsb pdb:5NK4|rcsb pdb:5NK5|rcsb pdb:5NK6|rcsb pdb:5NK7|rcsb pdb:5NK8|rcsb pdb:5NK9|rcsb pdb:5NKA|rcsb pdb:5NKB|rcsb pdb:5NKC|rcsb pdb:5NKD|rcsb pdb:5NKE|rcsb pdb:5NKF|rcsb pdb:5NKG|rcsb pdb:5NKH|rcsb pdb:5NKI|rcsb pdb:5NZ9|rcsb pdb:6B9L|rcsb pdb:6F7M|rcsb pdb:6F7N|rcsb pdb:6FNF|rcsb pdb:6NK1|rcsb pdb:6FNG|rcsb pdb:6FNH|rcsb pdb:6HES|rcsb pdb:6HET|rcsb pdb:6HEU|rcsb pdb:6HEV|rcsb pdb:6HEW|rcsb pdb:6HEX|rcsb pdb:6HEY|rcsb pdb:6NJZ|rcsb pdb:6NK0|rcsb pdb:6NK2|rcsb pdb:6NKP|rcsb pdb:6Q7B|rcsb pdb:6Q7C|rcsb pdb:6Q7D|rcsb pdb:6Q7E|rcsb pdb:6Q7F|rcsb pdb:6Q7G|rcsb pdb:6RW2|rcsb pdb:7B7N|rcsb pdb:7CZE|rcsb pdb:7CZF|rcsb pdb:7KJA|rcsb pdb:7KJB|rcsb pdb:7KJC|rcsb pdb:8BIN|rcsb pdb:8BIO|rcsb pdb:8BK0|rcsb pdb:8BM8|rcsb pdb:8BOC|rcsb pdb:8BOD|rcsb pdb:8BOF|rcsb pdb:8BOG|rcsb pdb:8BOH|rcsb pdb:8BOI|rcsb pdb:8BOK|rcsb pdb:8BOM|rcsb pdb:8QQY|rcsb pdb:8T9B|rcsb pdb:8TRS|rcsb pdb:8TRT|rcsb pdb:8TRV|rcsb pdb:8TV1|rcsb pdb:8TV5|rcsb pdb:8XPV|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_004422.2|efo:""Orphanet:441447""|efo:""Orphanet:98991""|efo:""Orphanet:98993""|efo:""Orphanet:98994""|dip:DIP-96N|panther:PTHR24416(orthology-group)|ensembl:ENSP00000351209.5"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:9VFikLd4ftRmEyBpY0JHdpHINT09606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P52292	intact:EBI-27033185	intact:EBI-349938|uniprotkb:Q9BRU5|intact:EBI-28977049|uniprotkb:B9EJD6|uniprotkb:Q53YE3|ensembl:ENSP00000332455.3|ensembl:ENSP00000438483.2|ensembl:ENSP00000462331.2|ensembl:ENSP00000463602.2|ensembl:ENSP00000504655.1|ensembl:ENSP00000504685.1|intact:EBI-9377406|uniprotkb:Q6NVW7	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENSG00000182481.10(gene)|ensembl:ENST00000330459.8(transcript)|ensembl:ENST00000537025.6(transcript)|ensembl:ENST00000579754.2(transcript)|ensembl:ENST00000584026.6(transcript)|ensembl:ENST00000677086.1(transcript)|ensembl:ENST00000679078.1(transcript)|go:""GO:0000018""(regulation of DNA recombination)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006259""(DNA metabolic process)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0042564""(NLS-dependent protein nuclear import complex)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043657""(host cell)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0075506""(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:""GO:1903902""(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7CRU|rcsb pdb:7N8J|rcsb pdb:7N9H|rcsb pdb:8FZK|rcsb pdb:8GCN|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|reactome:R-HSA-9692916|reactome:R-HSA-9705671|dip:DIP-6205N|panther:PTHR23316(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B5H5	uniprotkb:P12236	intact:EBI-27033185	intact:EBI-356254|uniprotkb:Q96C49|ensembl:ENSP00000370808.5|ensembl:ENSP00000518609.1	psi-mi:a0a0f6b5h5_salt1(display_long)|uniprotkb:pipB2(gene name)|psi-mi:pipB2(display_short)|uniprotkb:STM14_3350(locus name)	psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033251|imex:IM-29092-1	intact-miscore:0.46	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A0A0F6B5H5|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|interpro:IPR048984|refseq:WP_001738474.1|interpro:IPR001646(Pentapeptide repeat)"	"refseq:NP_001627.2|ensembl:ENSG00000169100.14(gene)|ensembl:ENSG00000292334.1(gene)|ensembl:ENST00000381401.11(transcript)|ensembl:ENST00000711214.1(transcript)|go:""GO:0005471""(""ATP:ADP antiporter activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005744""(TIM23 mitochondrial import inner membrane translocase complex)|go:""GO:0006915""(apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0140021""(mitochondrial ADP transmembrane transport)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1990544""(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|reactome:R-HSA-9837999|panther:PTHR45635(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/25	rogid:grcWpu0wnTnhuSBfXroAR2AqgrE588858	rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606	intact-crc:3AF88AE1A5F9E145|rigid:x6nW0wBuZpm6yDWm37lrHW0T3Xo	false	tandem tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q9Y2W1	intact:EBI-11477981	intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634.5|ensembl:ENSP00000433825.1	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_005110.2|refseq:NP_001308400.1|refseq:NP_001308402.1|ensembl:ENSG00000054118.15(gene)|ensembl:ENST00000354618.10(transcript)|ensembl:ENST00000469141.6(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016592""(mediator complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0042753""(positive regulation of circadian rhythm)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|panther:PTHR15268(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q9P253	intact:EBI-11477981	intact:EBI-1053363|uniprotkb:Q8TCG0|uniprotkb:Q96DI3|uniprotkb:Q9H268|ensembl:ENSP00000220509.5	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:vps18_human(display_long)|uniprotkb:VPS18(gene name)|psi-mi:VPS18(display_short)|uniprotkb:KIAA1475(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_065908.1|ensembl:ENSG00000104142.11(gene)|ensembl:ENST00000220509.10(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0005884""(actin filament)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007032""(endosome organization)|go:""GO:0007040""(lysosome organization)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030897""(HOPS complex)|go:""GO:0031902""(late endosome membrane)|go:""GO:0033147""(negative regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0033263""(CORVET complex)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0035542""(regulation of SNARE complex assembly)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048284""(organelle fusion)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)|mint:Q9P253|reactome:R-HSA-9754560|panther:PTHR23323(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:/MgSM2SvqrSP9a2BA5IFOvPrwHc9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q9NYF8	intact:EBI-11477981	intact:EBI-437804|ensembl:ENSP00000435210.1|uniprotkb:Q86WY0|uniprotkb:Q14673|uniprotkb:Q86WU6|uniprotkb:B7ZM58|uniprotkb:A2RU75|uniprotkb:E1P586	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:bclf1_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 1(gene name synonym)|uniprotkb:BCLAF1(gene name)|psi-mi:BCLAF1(display_short)|uniprotkb:BTF(gene name synonym)|uniprotkb:KIAA0164(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"ensembl:ENSG00000029363.17(gene)|ensembl:ENST00000531224.6(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0016592""(mediator complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR029199|mint:Q9NYF8|rcsb pdb:7RJN|rcsb pdb:7RJR|refseq:NP_001070908.1|refseq:NP_001070909.1|refseq:NP_055554.1|refseq:NP_001287967.1|panther:PTHR15268(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:v6qbjyjKVCv0B/olkjQfTPKWqBw9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q96JC1	intact:EBI-11477981	intact:EBI-1050197|uniprotkb:O94869|uniprotkb:Q7Z3V3|uniprotkb:Q96B93|uniprotkb:Q96RM0|uniprotkb:Q71SQ6|ensembl:ENSP00000335193.5	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:vps39_human(display_long)|uniprotkb:KIAA0770(gene name synonym)|uniprotkb:VPS39(gene name)|psi-mi:VPS39(display_short)|uniprotkb:VAM6(gene name synonym)|uniprotkb:TLP(gene name synonym)|uniprotkb:TRAP1-like protein(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_056104.2|refseq:NP_001288067.1|ensembl:ENSG00000166887.16(gene)|ensembl:ENST00000348544.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006914""(autophagy)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030897""(HOPS complex)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0035542""(regulation of SNARE complex assembly)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:1902501""(lysosomal HOPS complex)|go:""GO:1902774""(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001180(Citron-like)|interpro:IPR019452|interpro:IPR019453|interpro:IPR032914|mint:Q96JC1|rcsb pdb:6ZE9|reactome:R-HSA-9754560|panther:PTHR12894(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:BeY8ZDCOyTvZqA0WpdWnmz+giYk9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q9NYL2	intact:EBI-11477981	intact:EBI-602273|uniprotkb:Q53SX1|uniprotkb:Q580W8|uniprotkb:Q59GY5|uniprotkb:Q86YW8|uniprotkb:Q9HCC4|uniprotkb:Q9HCC5|uniprotkb:Q9HDD2|uniprotkb:Q9NYE9|intact:EBI-1058916|ensembl:ENSP00000364361.3|ensembl:ENSP00000387259.2|uniprotkb:B3KPG2	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:m3k20_human(display_long)|uniprotkb:Human cervical cancer suppressor gene 4 protein(gene name synonym)|uniprotkb:Leucine zipper- and sterile alpha motif-containing kinase(gene name synonym)|uniprotkb:MLK-like mitogen-activated protein triple kinase(gene name synonym)|uniprotkb:MLTK(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase MLT(gene name synonym)|uniprotkb:Mixed lineage kinase-related kinase(gene name synonym)|uniprotkb:Sterile alpha motif- and leucine zipper-containing kinase AZK(gene name synonym)|uniprotkb:ZAK(gene name synonym)|uniprotkb:HCCS4(orf name)|uniprotkb:MLK7(gene name synonym)|uniprotkb:Mixed lineage kinase 7(gene name synonym)|uniprotkb:MAP3K20(gene name)|psi-mi:MAP3K20(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"ensembl:ENSG00000091436.17(gene)|ensembl:ENST00000375213.8(transcript)|ensembl:ENST00000409176.6(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006954""(inflammatory response)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007254""(JNK cascade)|go:""GO:0008219""(cell death)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030154""(cell differentiation)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0031098""(stress-activated protein kinase signaling cascade)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0043022""(ribosome binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043068""(positive regulation of programmed cell death)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0060173""(limb development)|go:""GO:0070181""(small ribosomal subunit rRNA binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070303""(negative regulation of stress-activated protein kinase signaling cascade)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071493""(cellular response to UV-B)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140469""(GCN2-mediated signaling)|go:""GO:0170011""(stalled ribosome sensor activity)|go:""GO:1902010""(negative regulation of translation in response to endoplasmic reticulum stress)|go:""GO:1904291""(positive regulation of mitotic DNA damage checkpoint)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:7YAW|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR051681|mint:Q9NYL2|rcsb pdb:5HES|rcsb pdb:5X5O|rcsb pdb:6JUT|rcsb pdb:6JUU|rcsb pdb:7YAZ|refseq:NP_057737.2|refseq:NP_598407.1|refseq:XP_005246697.1|refseq:XP_016859812.1|refseq:XP_016859813.1|efo:""Orphanet:2020""|efo:""Orphanet:488232""|panther:PTHR43289(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:r8AGxedcm7rLHlwHGc0wKwzHXbM9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:P49754	intact:EBI-11477981	intact:EBI-2130459|uniprotkb:Q99851|uniprotkb:Q99852|uniprotkb:Q86TP8|uniprotkb:E9PF36|ensembl:ENSP00000309457.4	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:vps41_human(display_long)|uniprotkb:VPS41(gene name)|psi-mi:VPS41(display_short)|uniprotkb:S53(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"ensembl:ENSG00000006715.16(gene)|ensembl:ENST00000310301.9(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0008017""(microtubule binding)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010008""(endosome membrane)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030897""(HOPS complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0035542""(regulation of SNARE complex assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048193""(Golgi vesicle transport)|go:""GO:1902501""(lysosomal HOPS complex)|go:""GO:1902774""(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322|interpro:IPR045111|mint:P49754|reactome:R-HSA-9754560|refseq:NP_055211.2|refseq:NP_542198.2|efo:""Orphanet:95434""|panther:PTHR12616(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:ehH/zcBGZBo+HKWXQRxDgr0KcgI9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:P43243	intact:EBI-11477981	intact:EBI-352602|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5|ensembl:ENSP00000378284.3|ensembl:ENSP00000482895.1	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"ensembl:ENSG00000015479.20(gene)|ensembl:ENST00000394805.8(transcript)|ensembl:ENST00000618441.5(transcript)|go:""GO:0001825""(blastocyst formation)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003170""(heart valve development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005634""(nucleus)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_001181885.1|refseq:NP_001269207.1|refseq:NP_061322.2|refseq:NP_954659.1|efo:""Orphanet:600""|efo:""Orphanet:803""|panther:PTHR15592(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:P98175	intact:EBI-11477981	intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|ensembl:ENSP00000366829.3|uniprotkb:A0A0A0MR66	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"efo:""Orphanet:2886""|ensembl:ENSG00000182872.16(gene)|ensembl:ENST00000377604.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048025""(negative regulation of mRNA splicing, via spliceosome)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1905288""(vascular associated smooth muscle cell apoptotic process)|go:""GO:1905461""(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:""GO:1990874""(vascular associated smooth muscle cell proliferation)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_001191397.1|refseq:NP_005667.2|refseq:NP_690595.1|panther:PTHR13948(orthology-group)|ensembl:ENST00000329236.8|ensembl:ENSP00000328848.8|ensembl:ENST00000345781.10|ensembl:ENSP00000329659.6|ensembl:ENSP00000366829.3|ensembl:ENST00000628161.2|ensembl:ENSP00000486115.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:O60583	intact:EBI-11477981	intact:EBI-2836757|uniprotkb:Q5I1Y0|uniprotkb:A8KA48|uniprotkb:Q29R66|uniprotkb:Q53SR4|uniprotkb:O60582|ensembl:ENSP00000264157.5|uniprotkb:D3DP73|uniprotkb:D3DP74	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:ccnt2_human(display_long)|uniprotkb:CCNT2(gene name)|psi-mi:CCNT2(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"ensembl:ENSG00000082258.13(gene)|ensembl:ENST00000264157.10(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0008024""(cyclin/CDK positive transcription elongation factor complex)|go:""GO:0019085""(early viral transcription)|go:""GO:0019086""(late viral transcription)|go:""GO:0019901""(protein kinase binding)|go:""GO:0032786""(positive regulation of DNA-templated transcription, elongation)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051147""(regulation of muscle cell differentiation)|go:""GO:0051301""(cell division)|go:""GO:0061575""(cyclin-dependent protein serine/threonine kinase activator activity)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0097322""(7SK snRNA binding)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|interpro:IPR047321|interpro:IPR047322|mint:O60583|rcsb pdb:2IVX|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|refseq:NP_001232.1|refseq:NP_490595.1|panther:PTHR10026(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:v1mUPCNA+Plg8UioUhIj1LL52fI9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q9H270	intact:EBI-11477981	intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"efo:""Orphanet:466934""|go:""GO:0000166""(nucleotide binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007032""(endosome organization)|go:""GO:0007033""(vacuole organization)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030897""(HOPS complex)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031902""(late endosome membrane)|go:""GO:0033147""(negative regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0033263""(CORVET complex)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0035542""(regulation of SNARE complex assembly)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0048284""(organelle fusion)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:1902115""(regulation of organelle assembly)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|reactome:R-HSA-9754560|refseq:NP_001277114.1|refseq:NP_068375.3|panther:PTHR23323(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q8N163	intact:EBI-11477981	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|uniprotkb:B2RB79|uniprotkb:D3DSR6|ensembl:ENSP00000310670.4|ensembl:ENSP00000373930.3	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_066997.3|ensembl:ENSG00000158941.17(gene)|ensembl:ENST00000308511.9(transcript)|ensembl:ENST00000389279.7(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005819""(spindle)|go:""GO:0006397""(mRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0008380""(RNA splicing)|go:""GO:0009411""(response to UV)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032784""(regulation of DNA-templated transcription elongation)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0044609""(DBIRD complex)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048511""(rhythmic process)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090311""(regulation of protein deacetylation)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:2000003""(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR045353|interpro:IPR045354|mint:Q8N163|rcsb pdb:8EZ6|reactome:R-HSA-3371453|dip:DIP-38122N"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q01804	intact:EBI-11477981	intact:EBI-1054396|uniprotkb:Q147U2|uniprotkb:Q1ZYK1|uniprotkb:Q6PG39|uniprotkb:Q96MQ5|uniprotkb:Q9NT94|uniprotkb:Q9UPV6|uniprotkb:B4DYS4|ensembl:ENSP00000395487.2	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:otud4_human(display_long)|uniprotkb:HIN-1(gene name synonym)|uniprotkb:HIV-1-induced protein HIN-1(gene name synonym)|uniprotkb:OTUD4(gene name)|psi-mi:OTUD4(display_short)|uniprotkb:KIAA1046(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:XP_005263136.1|refseq:NP_001096123.1|refseq:NP_059963.1|ensembl:ENSG00000164164.17(gene)|ensembl:ENST00000447906.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006307""(DNA alkylation repair)|go:""GO:0006508""(proteolysis)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0035871""(protein K11-linked deubiquitination)|go:""GO:0045087""(innate immune response)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061578""(K63-linked deubiquitinase activity)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1903093""(regulation of protein K48-linked deubiquitination)|go:""GO:2000660""(negative regulation of interleukin-1-mediated signaling pathway)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR038765|interpro:IPR050704|mint:Q01804|panther:PTHR12419(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:humMGfho0HKWE4zhO7+G00gIJfc9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q5SW79	intact:EBI-11477981	intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500.1|ensembl:ENSP00000483344.1	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702.17(gene)|ensembl:ENSG00000276725.4(gene)|ensembl:ENST00000366542.6(transcript)|ensembl:ENST00000612450.4(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0120103""(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029300|interpro:IPR051176|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N|panther:PTHR15715(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:P52756	intact:EBI-11477981	intact:EBI-714003|uniprotkb:Q93021|uniprotkb:Q9BU14|uniprotkb:Q9UKY8|uniprotkb:Q9UL24|uniprotkb:B2RA45|uniprotkb:B4DM16|uniprotkb:B4DMF9|uniprotkb:B4DZ63|uniprotkb:Q9HDA6|ensembl:ENSP00000343054.3|intact:EBI-16431417	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:rbm5_human(display_long)|uniprotkb:RNA-binding motif protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor LUCA15(gene name synonym)|uniprotkb:Protein G15(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-9(gene name synonym)|uniprotkb:RBM5(gene name)|psi-mi:RBM5(display_short)|uniprotkb:H37(orf name)|uniprotkb:LUCA15(orf name)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_005769.1|ensembl:ENSG00000003756.17(gene)|ensembl:ENST00000347869.8(transcript)|go:""GO:0000245""(spliceosomal complex assembly)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006396""(RNA processing)|go:""GO:0006915""(apoptotic process)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034991|interpro:IPR034993|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P52756|rcsb pdb:2LK0|rcsb pdb:2LK1|rcsb pdb:2LKZ|rcsb pdb:5MF9|rcsb pdb:5MFY|rcsb pdb:7PCV|rcsb pdb:7PDV|reactome:R-HSA-72163|refseq:XP_016860992.1|dip:DIP-47277N|panther:PTHR13948(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:LsPTpaKrGY2xtpYofHbFVXjSi/A9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:O43290	intact:EBI-11477981	intact:EBI-607761|uniprotkb:A6NDN1|uniprotkb:Q53GB5|ensembl:ENSP00000310448.5	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:snut1_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 110 kDa protein(gene name synonym)|uniprotkb:SART1(gene name)|psi-mi:SART1(display_short)|uniprotkb:SNU66 homolog(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_005137.1|ensembl:ENSG00000175467.15(gene)|ensembl:ENST00000312397.10(transcript)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000481""(maturation of 5S rRNA)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0015030""(Cajal body)|go:""GO:0016607""(nuclear speck)|go:""GO:0045292""(mRNA cis splicing, via spliceosome)|go:""GO:0045585""(positive regulation of cytotoxic T cell differentiation)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|interpro:IPR005011(SART-1 protein)|interpro:IPR045347|mint:O43290|rcsb pdb:4PYU|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8Q7N|rcsb pdb:8QO9|rcsb pdb:8QOZ|rcsb pdb:8QP8|rcsb pdb:8QP9|rcsb pdb:8QPA|rcsb pdb:8QPB|rcsb pdb:8QPE|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RM5|rcsb pdb:8Y6O|reactome:R-HSA-72163|dip:DIP-33360N|panther:PTHR14152(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:egvWHy7UXW+MkGtGEW984yvRU9k9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:O43143	intact:EBI-11477981	intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741.4	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym)|uniprotkb:Splicing factor Prp43(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_001349.2|ensembl:ENSG00000109606.13(gene)|ensembl:ENST00000336812.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005689""(U12-type spliceosomal complex)|go:""GO:0005730""(nucleolus)|go:""GO:0006397""(mRNA processing)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0008380""(RNA splicing)|go:""GO:0009636""(response to toxic substance)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043279""(response to alkaloid)|go:""GO:0051607""(defense response to virus)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|interpro:IPR048333|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|rcsb pdb:8EJM|rcsb pdb:8RO2|reactome:R-HSA-72163|dip:DIP-38211N|panther:PTHR18934(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q96AX1	intact:EBI-11477981	intact:EBI-2527283|uniprotkb:Q547V4|uniprotkb:Q9H5Q0|ensembl:ENSP00000267199.3	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:vp33a_human(display_long)|uniprotkb:VPS33A(gene name)|psi-mi:VPS33A(display_short)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"ensembl:ENSG00000139719.12(gene)|ensembl:ENST00000267199.9(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030220""(platelet formation)|go:""GO:0030897""(HOPS complex)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032400""(melanosome localization)|go:""GO:0032418""(lysosome localization)|go:""GO:0033263""(CORVET complex)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0035542""(regulation of SNARE complex assembly)|go:""GO:0035751""(regulation of lysosomal lumen pH)|go:""GO:0048070""(regulation of developmental pigmentation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0097352""(autophagosome maturation)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q96AX1|rcsb pdb:4BX8|rcsb pdb:4BX9|reactome:R-HSA-9754560|refseq:NP_075067.2|efo:""Orphanet:505248""|panther:PTHR11679(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:dtPjiiMZ60tlBdhBPrYBHkXAUpE9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q9UII4	intact:EBI-11477981	intact:EBI-2339540|uniprotkb:B2RTQ1|uniprotkb:Q69G20|ensembl:ENSP00000264350.3|intact:EBI-28975860	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:herc5_human(display_long)|uniprotkb:HERC5(gene name)|psi-mi:HERC5(display_short)|uniprotkb:CEB1(gene name synonym)|uniprotkb:CEBP1(gene name synonym)|uniprotkb:HECT domain and RCC1-like domain-containing protein 5(gene name synonym)|uniprotkb:Cyclin-E-binding protein 1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_057407.2|dip:DIP-44200N|ensembl:ENSG00000138646.9(gene)|ensembl:ENST00000264350.8(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032020""(ISG15-protein conjugation)|go:""GO:0039585""(PKR/eIFalpha signaling)|go:""GO:0042296""(ISG15 transferase activity)|go:""GO:0045087""(innate immune response)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050688""(regulation of defense response to virus)|go:""GO:0051607""(defense response to virus)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000569(HECT)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR035983|interpro:IPR051709|mint:Q9UII4|rcsb pdb:8Y4Z|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-936440|reactome:R-HSA-983168|reactome:R-HSA-9833110|reactome:R-HSA-9833482|panther:PTHR45622(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:IGuce5qcdMB8PC5u6b6A57FODKY9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q15233	intact:EBI-11477981	intact:EBI-350527|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3|ensembl:ENSP00000276079.8|ensembl:ENSP00000362947.1|ensembl:ENSP00000406673.2|ensembl:ENSP00000410299.2|ensembl:ENSP00000415777.2|ensembl:ENSP00000503031.1|ensembl:ENSP00000503233.1|ensembl:ENSP00000504314.1|ensembl:ENSP00000504351.1	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"efo:""Orphanet:319308""|efo:""Orphanet:466791""|ensembl:ENSG00000147140.17(gene)|ensembl:ENST00000276079.13(transcript)|ensembl:ENST00000373841.5(transcript)|ensembl:ENST00000420903.6(transcript)|ensembl:ENST00000450092.6(transcript)|ensembl:ENST00000454976.2(transcript)|ensembl:ENST00000677274.1(transcript)|ensembl:ENST00000677446.1(transcript)|ensembl:ENST00000677612.1(transcript)|ensembl:ENST00000678231.1(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0042382""(paraspeckles)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903377""(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|rcsb pdb:7PU5|refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|dip:DIP-29951N|panther:PTHR23189(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q15646	intact:EBI-11477981	intact:EBI-3918068|uniprotkb:Q9Y6K7|uniprotkb:O75686|uniprotkb:Q17R95|uniprotkb:Q9Y6K6|ensembl:ENSP00000257570.4|uniprotkb:B2RAZ2|uniprotkb:I1YDD2	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:oasl_human(display_long)|uniprotkb:OASL(gene name)|psi-mi:OASL(display_short)|uniprotkb:TRIP14(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 14(gene name synonym)|uniprotkb:p59 OASL(gene name synonym)|uniprotkb:2'-5'-OAS-related protein(gene name synonym)|uniprotkb:59 kDa 2'-5'-oligoadenylate synthase-like protein(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"refseq:NP_003724.1|ensembl:ENSG00000135114.14(gene)|ensembl:ENST00000257570.10(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0070106""(interleukin-27-mediated signaling pathway)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1900246""(positive regulation of RIG-I signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR029071|interpro:IPR043518|interpro:IPR043519|mint:Q15646|rcsb pdb:1WH3|rcsb pdb:4XQ7|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:NP_001248754.1|refseq:NP_937856.1|refseq:XP_016875630.1|panther:PTHR11258(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:8xjzLMgnkgdKUeTlp9hrr3iQIiM9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:P51532	intact:EBI-11477981	intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896.4|ensembl:ENSP00000395654.1	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"efo:""Orphanet:1465""|efo:""Orphanet:231108""|efo:""Orphanet:370396""|efo:""Orphanet:466962""|ensembl:ENSG00000127616.22(gene)|ensembl:ENST00000344626.10(transcript)|ensembl:ENST00000429416.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0001188""(RNA polymerase I preinitiation complex assembly)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001650""(fibrillar center)|go:""GO:0002039""(p53 binding)|go:""GO:0003407""(neural retina development)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006337""(nucleosome disassembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007399""(nervous system development)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0016787""(hydrolase activity)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042393""(histone binding)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0071564""(npBAF complex)|go:""GO:0071565""(nBAF complex)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140092""(bBAF complex)|go:""GO:0140288""(GBAF complex)|go:""GO:0140658""(ATP-dependent chromatin remodeler activity)|go:""GO:0140750""(nucleosome array spacer activity)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:1902661""(positive regulation of glucose mediated signaling pathway)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|interpro:IPR049730|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|rcsb pdb:7TAB|rcsb pdb:7TD9|rcsb pdb:7VDT|rcsb pdb:7VDV|rcsb pdb:7VRB|rcsb pdb:7Y8R|rcsb pdb:8EB1|rcsb pdb:8G1Q|rcsb pdb:8QJR|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665|reactome:R-HSA-9824585|reactome:R-HSA-9845323|refseq:NP_001122316.1|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|refseq:NP_003063.2|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|dip:DIP-24249N|ensembl:ENSP00000343896.4|ensembl:ENSP00000395654.1|ensembl:ENST00000444061.8|ensembl:ENSP00000392837.2|ensembl:ENST00000541122.6|ensembl:ENSP00000445036.2|ensembl:ENST00000589677.5|ensembl:ENSP00000464778.1|ensembl:ENST00000590574.6|ensembl:ENSP00000466963.1|ensembl:ENST00000643296.1|ensembl:ENSP00000496635.1|ensembl:ENST00000644737.1|ensembl:ENSP00000495548.1|ensembl:ENST00000645460.1|ensembl:ENSP00000494463.1|ensembl:ENST00000646484.1|ensembl:ENSP00000495536.1|ensembl:ENST00000646510.1|ensembl:ENSP00000494772.1|ensembl:ENST00000647230.1|ensembl:ENSP00000494676.1|panther:PTHR10799(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:P06748	intact:EBI-11477981	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0F6B063	uniprotkb:Q06787	intact:EBI-11477981	intact:EBI-366305|uniprotkb:Q5PQZ6|uniprotkb:Q16578|uniprotkb:Q99054|uniprotkb:A6NNH4|uniprotkb:D3DWT0|uniprotkb:D3DWT1|uniprotkb:D3DWT2|uniprotkb:G8JL90|ensembl:ENSP00000359506.5	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:fmr1_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|uniprotkb:Fragile X messenger ribonucleoprotein(gene name synonym)|uniprotkb:Protein FMR-1(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Walch et al. (2021)	pubmed:34237247|imex:IM-29092	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-27033283|imex:IM-29092-61	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"efo:""Orphanet:261483""|efo:""Orphanet:449291""|efo:""Orphanet:642691""|efo:""Orphanet:908""|efo:""Orphanet:93256""|ensembl:ENSG00000102081.16(gene)|ensembl:ENST00000370475.9(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0002151""(G-quadruplex RNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006397""(mRNA processing)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0007215""(glutamate receptor signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008017""(microtubule binding)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008380""(RNA splicing)|go:""GO:0010369""(chromocenter)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015030""(Cajal body)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030371""(translation repressor activity)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0032433""(filopodium tip)|go:""GO:0033592""(RNA strand annealing activity)|go:""GO:0034046""(""poly(G) binding"")|go:""GO:0034063""(stress granule assembly)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035197""(siRNA binding)|go:""GO:0035198""(miRNA binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042995""(cell projection)|go:""GO:0043005""(neuron projection)|go:""GO:0043022""(ribosome binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0043204""(perikaryon)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0043679""(axon terminus)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044830""(modulation by host of viral RNA genome replication)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045202""(synapse)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0046928""(regulation of neurotransmitter secretion)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0048170""(positive regulation of long-term neuronal synaptic plasticity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048513""(animal organ development)|go:""GO:0051028""(mRNA transport)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0060965""(negative regulation of miRNA-mediated gene silencing)|go:""GO:0060998""(regulation of dendritic spine development)|go:""GO:0060999""(positive regulation of dendritic spine development)|go:""GO:0070840""(dynein complex binding)|go:""GO:0071598""(neuronal ribonucleoprotein granule)|go:""GO:0097386""(glial cell projection)|go:""GO:0098586""(cellular response to virus)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098908""(regulation of neuronal action potential)|go:""GO:0099577""(regulation of translation at presynapse, modulating synaptic transmission)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|go:""GO:1900453""(negative regulation of long-term synaptic depression)|go:""GO:1901254""(positive regulation of intracellular transport of viral material)|go:""GO:1901386""(negative regulation of voltage-gated calcium channel activity)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|go:""GO:1902737""(dendritic filopodium)|go:""GO:1990247""(N6-methyladenosine-containing RNA reader activity)|go:""GO:1990812""(growth cone filopodium)|go:""GO:1990825""(sequence-specific mRNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000301""(negative regulation of synaptic vesicle exocytosis)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|go:""GO:2000766""(negative regulation of cytoplasmic translation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|interpro:IPR047431|interpro:IPR047436|interpro:IPR047438|interpro:IPR047440|mint:Q06787|rcsb pdb:2BKD|rcsb pdb:2FMR|rcsb pdb:2LA5|rcsb pdb:2QND|rcsb pdb:4OVA|rcsb pdb:4QVZ|rcsb pdb:4QW2|rcsb pdb:5DE5|rcsb pdb:5DE8|rcsb pdb:5DEA|rcsb pdb:5UWJ|rcsb pdb:5UWO|refseq:NP_001172004.1|refseq:NP_001172005.1|refseq:NP_001172010.1|refseq:NP_001172011.1|refseq:NP_002015.1|dip:DIP-29509N|panther:PTHR10603(orthology-group)"	-	-	-	figure legend:ST2 F3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2021/07/12	2025/03/23	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:+iN/J/MbxTcRwgDezYseEDwLep49606	intact-crc:8CDA0EDD1A095919|rigid:KhKAtWEm/rK3fS7soWV18KO66VY	false	tandem tag:136-137	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q92888	uniprotkb:Q7DB74	intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532.3	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym)	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7864798|mint:MINT-7909075|imex:IM-15070-8	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|panther:PTHR45872(orthology-group)|ensembl:ENSG00000076928.20(gene)|ensembl:ENST00000354532.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|interpro:IPR044926|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:MINT-7909077(identity)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7909078(identity)	-	-	comment:mint	figure legend:f4a|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/06/21	2024/11/14	rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	intact-crc:8B3EA49F08AE1E05|rigid:YaIENMSkEIOxlUW7iehPAo1wN1U	false	binding-associated region:421-760(MINT-7909082)|flag tag:?-?(MINT-7909079)	myc tag:?-?(MINT-7909085)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q92888	uniprotkb:Q7DB74	intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532.3	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym)	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7864852|mint:MINT-7909421|imex:IM-15070-9	intact-miscore:0.60	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|panther:PTHR45872(orthology-group)|ensembl:ENSG00000076928.20(gene)|ensembl:ENST00000354532.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|interpro:IPR044926|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:MINT-7909423(identity)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7909429(identity)	-	-	comment:mint	figure legend:f5a|comment:homomint|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/06/21	2024/11/14	rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	intact-crc:EBF34417A8BA4C3F|rigid:XTfgBMeR2/y/isIbSLfDTENG6BA	false	binding-associated region:421-760(MINT-7909424)|flag tag:?-?(MINT-7909426)	myc tag:?-?(MINT-7909430)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q92888	uniprotkb:Q7DB74	intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532.3	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym)	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7864879|mint:MINT-7909440|imex:IM-15070-10	intact-miscore:0.60	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|panther:PTHR45872(orthology-group)|ensembl:ENSG00000076928.20(gene)|ensembl:ENST00000354532.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|interpro:IPR044926|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:MINT-7909442(identity)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7909448(identity)	-	-	comment:mint	figure legend:f5a|comment:homomint|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/06/21	2024/11/14	rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	intact-crc:A23A80587A328F8D|rigid:snSQzt03b438U8SdGSD6CvNI1KI	false	binding-associated region:421-760(MINT-7909445)|flag tag:?-?(MINT-7909443)	myc tag:?-?(MINT-7909449)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:O15085	uniprotkb:Q7DB74	intact:EBI-311099|intact:EBI-28988539|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2|ensembl:ENSP00000354644.2	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym)	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7865085|mint:MINT-7949812|imex:IM-15070-15	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055599.1|refseq:NP_937879.1|ensembl:ENSG00000132694.20(gene)|ensembl:ENST00000361409.2(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006941""(striated muscle contraction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|interpro:IPR044926|mint:O15085|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|dip:DIP-31622N|panther:PTHR45872(orthology-group)|mint:MINT-7949814(identity)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7949824(identity)	-	-	comment:mint	figure legend:f5d|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/06/21	2024/11/14	rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	intact-crc:D3C4308BF568160F|rigid:rVnhyOUvRGcMVJHkUIviThALJsA	false	flag tag:?-?(MINT-7949819)|mutation decreasing interaction:748-748(MINT-7949815)|binding-associated region:734-1079(MINT-7949821)|mutation decreasing interaction:741-741(MINT-7949817)	myc tag:?-?(MINT-7949825)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q7DB74	uniprotkb:O15085	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	intact:EBI-311099|intact:EBI-28988539|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2|ensembl:ENSP00000354644.2	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7865179|mint:MINT-7949847|imex:IM-15070-17	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7949862(identity)	"refseq:NP_055599.1|refseq:NP_937879.1|ensembl:ENSG00000132694.20(gene)|ensembl:ENST00000361409.2(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006941""(striated muscle contraction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|interpro:IPR044926|mint:O15085|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|dip:DIP-31622N|panther:PTHR45872(orthology-group)|mint:MINT-7949850(identity)"	-	comment:mint	-	figure legend:f5d|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/06/21	2024/11/14	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606	intact-crc:C65C1DF0903CCEF1|rigid:rVnhyOUvRGcMVJHkUIviThALJsA	false	myc tag:?-?(MINT-7949863)	mutation decreasing interaction:876-876(MINT-7949857)|binding-associated region:734-1079(MINT-7949853)|mutation decreasing interaction:873-873(MINT-7949855)|mutation decreasing interaction:872-872(MINT-7949859)|flag tag:?-?(MINT-7949851)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q7DB74	uniprotkb:O15085	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	intact:EBI-311099|intact:EBI-28988539|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2|ensembl:ENSP00000354644.2	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7865130|mint:MINT-7949829|imex:IM-15070-16	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7949843(identity)	"refseq:NP_055599.1|refseq:NP_937879.1|ensembl:ENSG00000132694.20(gene)|ensembl:ENST00000361409.2(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006941""(striated muscle contraction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|interpro:IPR044926|mint:O15085|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|dip:DIP-31622N|panther:PTHR45872(orthology-group)|mint:MINT-7949831(identity)"	-	comment:mint	-	figure legend:f5d|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/06/21	2024/11/14	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606	intact-crc:841CBD837D33F464|rigid:rVnhyOUvRGcMVJHkUIviThALJsA	false	myc tag:?-?(MINT-7949844)	mutation decreasing interaction:869-869(MINT-7949832)|mutation decreasing interaction:868-868(MINT-7949834)|mutation decreasing interaction:867-867(MINT-7949836)|flag tag:?-?(MINT-7949840)|binding-associated region:734-1079(MINT-7949838)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q92888	uniprotkb:Q7DB74	intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532.3	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym)	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	"psi-mi:""MI:0096""(pull down)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7865258|mint:MINT-7909090|imex:IM-15070-7	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|panther:PTHR45872(orthology-group)|ensembl:ENSG00000076928.20(gene)|ensembl:ENST00000354532.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|interpro:IPR044926|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:MINT-7909092(identity)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7909098(identity)	-	-	comment:mint	figure legend:f4d|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	-	2010/06/21	2024/11/14	rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	intact-crc:DF1532677446922C|rigid:YaIENMSkEIOxlUW7iehPAo1wN1U	false	glutathione s tranferase tag:?-?(MINT-7909095)|binding-associated region:421-760(MINT-7909093)	flag tag:?-?(MINT-7909099)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q92888	uniprotkb:Q7DB74	intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532.3	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym)	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	"psi-mi:""MI:0096""(pull down)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7865287|mint:MINT-7909110|imex:IM-15070-3	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|panther:PTHR45872(orthology-group)|ensembl:ENSG00000076928.20(gene)|ensembl:ENST00000354532.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|interpro:IPR044926|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:MINT-7909112(identity)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7909118(identity)	-	-	comment:mint	figure legend:f4c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/21	2024/11/14	rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	intact-crc:055D044728E7C048|rigid:YaIENMSkEIOxlUW7iehPAo1wN1U	false	maltose binding protein tag:?-?(MINT-7909136)|binding-associated region:421-760(MINT-7909115)	flag tag:?-?(MINT-7909119)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9NZN5	uniprotkb:Q7DB74	intact:EBI-821440|uniprotkb:O15086|uniprotkb:Q6P526|ensembl:ENSP00000380942.2	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	psi-mi:arhgc_human(display_long)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	"psi-mi:""MI:0096""(pull down)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7865324|mint:MINT-7949690|imex:IM-15070-4	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001185594.1|refseq:NP_056128.1|refseq:XP_011541022.1|refseq:XP_016872910.1|refseq:NP_001288013.1|dip:DIP-37887N|ensembl:ENSG00000196914.9(gene)|ensembl:ENST00000397843.7(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016020""(membrane)|rcsb pdb:2OS6|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037801|interpro:IPR037884|interpro:IPR041020|interpro:IPR044926|mint:Q9NZN5|rcsb pdb:1TXD|rcsb pdb:1X86|rcsb pdb:2OMJ|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|panther:PTHR45872(orthology-group)|mint:MINT-7949692(identity)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7949698(identity)	-	-	comment:mint	figure legend:f4c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/21	2024/11/14	rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	intact-crc:4B14C1C3E9853048|rigid:ASd0bS7BuhTRPFtfmNYYrK2AzFo	false	binding-associated region:787-1132(MINT-7949695)|maltose binding protein tag:?-?(MINT-7949693)	flag tag:?-?(MINT-7949699)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q7DB74	uniprotkb:O15085	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	intact:EBI-311099|intact:EBI-28988539|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2|ensembl:ENSP00000354644.2	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7865361|mint:MINT-7949704|imex:IM-15070-5	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7949706(identity)	"refseq:NP_055599.1|refseq:NP_937879.1|ensembl:ENSG00000132694.20(gene)|ensembl:ENST00000361409.2(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006941""(striated muscle contraction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|interpro:IPR044926|mint:O15085|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|dip:DIP-31622N|panther:PTHR45872(orthology-group)|mint:MINT-7949710(identity)"	-	comment:mint	-	figure legend:f4c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/06/21	2024/11/14	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606	intact-crc:80252818F982FB67|rigid:rVnhyOUvRGcMVJHkUIviThALJsA	false	flag tag:?-?(MINT-7949707)	maltose binding protein tag:?-?(MINT-7949713)|binding-associated region:734-1079(MINT-7949711)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q92888	uniprotkb:Q7DB74	intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532.3	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym)	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7865426|mint:MINT-7909139|imex:IM-15070-2	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|panther:PTHR45872(orthology-group)|ensembl:ENSG00000076928.20(gene)|ensembl:ENST00000354532.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|interpro:IPR044926|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:MINT-7909141(identity)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7909147(identity)	"go:""GO:0005886""(plasma membrane)"	-	comment:mint	figure legend:f6a|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:10090(mouse-raw264_7)|taxid:10090(Mus musculus monocyte macrophage cell line RAW264)	-	2010/06/21	2024/11/14	rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	intact-crc:04F4C1052B432FD3|rigid:YaIENMSkEIOxlUW7iehPAo1wN1U	false	flag tag:?-?(MINT-7909142)	green fluorescent protein tag:?-?(MINT-7909148)	-	-	"psi-mi:""MI:0707""(anti tag immunostaining)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q92888	uniprotkb:Q7DB74	intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532.3	intact:EBI-7864788|intact:MINT-7909067|uniprotkb:Q7A9P8|uniprotkb:A0A0H3JIR6|uniprotkb:A0A6M0JLB9	psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym)	psi-mi:q7db74_eco57(display_long)|uniprotkb:espH(gene name)|psi-mi:espH(display_short)|uniprotkb:ECs_4564(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Dong et al. (2010)	pubmed:20300064|imex:IM-15070|mint:MINT-7909059|doi:10.1038/emboj.2010.33	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7865471|mint:MINT-7909159|imex:IM-15070-1	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|panther:PTHR45872(orthology-group)|ensembl:ENSG00000076928.20(gene)|ensembl:ENST00000354532.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|interpro:IPR044926|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:MINT-7909161(identity)"	mint:Q7DB74|refseq:WP_001302249.1|refseq:NP_312591.1|mint:MINT-7909167(identity)	-	-	comment:mint	figure legend:f6b f6c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:10090(mouse-raw264_7)|taxid:10090(Mus musculus monocyte macrophage cell line RAW264)	-	2010/06/21	2024/11/14	rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606	rogid:pOFJ4el6t8lZJVfYlIV73rdhP/U83334	intact-crc:437E8BAF73F29285|rigid:YaIENMSkEIOxlUW7iehPAo1wN1U	false	flag tag:?-?(MINT-7909164)|binding-associated region:421-760(MINT-7909162)	myc tag:?-?(MINT-7909168)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398022|mint:MINT-7991103|imex:IM-15630-1	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991105(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991106(identity)"	-	-	comment:mint	comment:mint|figure legend:f2a f5a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:8DFB3BC8CD85C864|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	his tag:?-?(MINT-7991108)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398057|mint:MINT-7991126|imex:IM-15630-3	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991128(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991130(identity)"	-	-	comment:mint	figure legend:f2a|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:4D284710777E73E6|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:546-572(MINT-7991133)|glutathione s tranferase tag:?-?(MINT-7991150)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398037|mint:MINT-7991114|imex:IM-15630-2	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991120(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991116(identity)"	-	-	comment:mint	figure legend:f2a|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:11F582C8C0974377|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:481-515(MINT-7991123)|glutathione s tranferase tag:?-?(MINT-7991117)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398077|mint:MINT-7991138|imex:IM-15630-4	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991144(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991140(identity)"	-	-	comment:mint	figure legend:f2a|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:47FCDCD8AAF624E7|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:573-603(MINT-7991141)|glutathione s tranferase tag:?-?(MINT-7991147)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398097|mint:MINT-7991153|imex:IM-15630-5	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991155(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991157(identity)"	-	-	comment:mint	figure legend:f2a|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:738EFB0AE2E77F1C|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:699-736(MINT-7991160)|glutathione s tranferase tag:?-?(MINT-7991158)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398117|mint:MINT-7991165|imex:IM-15630-6	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991173(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991167(identity)"	-	-	comment:mint	figure legend:f2a|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:7323B0812EFC96AF|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:737-774(MINT-7991168)|glutathione s tranferase tag:?-?(MINT-7991170)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398204|mint:MINT-7991227|imex:IM-15630-9	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991233(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991229(identity)"	-	-	comment:mint	figure legend:f2c|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:D32421AC78199834|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:512-550(MINT-7991236)|glutathione s tranferase tag:?-?(MINT-7991230)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398183|mint:MINT-7991189|imex:IM-15630-8	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991195(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991191(identity)"	-	-	comment:mint	comment:mint|figure legend:f2c f6a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:408BBCBE0EDBB1A7|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	his tag:?-?(MINT-7991192)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398137|mint:MINT-7991177|imex:IM-15630-7	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991179(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991181(identity)"	-	-	comment:mint	figure legend:f2a|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:70215DFE6393339A|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:775-810(MINT-7991184)|glutathione s tranferase tag:?-?(MINT-7991182)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398282|mint:MINT-7991279|imex:IM-15630-12	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991281(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991283(identity)"	-	-	comment:mint	figure legend:f2c|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:3608D4B5B5C31582|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:763-800(MINT-7991286)|glutathione s tranferase tag:?-?(MINT-7991284)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398242|mint:MINT-7991253|imex:IM-15630-10	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991255(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991257(identity)"	-	-	comment:mint	figure legend:f2c|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:F587E92A1F9D9377|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:610-636(MINT-7991260)|glutathione s tranferase tag:?-?(MINT-7991258)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398262|mint:MINT-7991266|imex:IM-15630-11	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991275(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991268(identity)"	-	-	comment:mint	figure legend:f2c|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:4B4C46D683014715|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:637-672(MINT-7991269)|glutathione s tranferase tag:?-?(MINT-7991272)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398302|mint:MINT-7991292|imex:IM-15630-13	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991301(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991294(identity)"	-	-	comment:mint	figure legend:f2c|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:FCE5365AF754D7C5|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:801-838(MINT-7991295)|glutathione s tranferase tag:?-?(MINT-7991298)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398322|mint:MINT-7991305|imex:IM-15630-14	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991307(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991309(identity)"	-	-	comment:mint	figure legend:f2c|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:E50FCED7DD090565|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:839-874(MINT-7991312)|glutathione s tranferase tag:?-?(MINT-7991310)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398342|mint:MINT-7991622|imex:IM-15630-15	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991628(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991624(identity)"	-	-	comment:mint	figure legend:f7b|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:2F4DF68A34BF658F|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:790-800(MINT-7991632)|glutathione s tranferase tag:?-?(MINT-7991625)	-	-	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398389|mint:MINT-7991345|imex:IM-15630-17	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991347(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991349(identity)"	-	-	comment:mint	figure legend:f2b|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:7DC0ADA0935FD229|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:481-515(MINT-7991352)|glutathione s tranferase tag:?-?(MINT-7991350)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398409|mint:MINT-7991360|imex:IM-15630-18	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991369(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991362(identity)"	-	-	comment:mint	figure legend:f2b|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:211D687824B6E2B8|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:546-572(MINT-7991365)|glutathione s tranferase tag:?-?(MINT-7991363)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q53682	uniprotkb:P02751	intact:EBI-8398005|intact:MINT-7991086	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398371|mint:MINT-7991321|imex:IM-15630-16	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991323(identity)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991327(identity)"	-	comment:mint	-	comment:mint|figure legend:f2b f5b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:C42E8E32B83923EE|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	his tag:?-?(MINT-7991324)	his tag:?-?(MINT-7991332)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398429|mint:MINT-7991375|imex:IM-15630-19	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991377(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991379(identity)"	-	-	comment:mint	figure legend:f2b|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:2BC9F3B0F93EB5B9|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:573-603(MINT-7991382)|glutathione s tranferase tag:?-?(MINT-7991380)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398449|mint:MINT-7991390|imex:IM-15630-20	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991399(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991392(identity)"	-	-	comment:mint	figure legend:f2b|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:1FBBD462B12FEE42|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:699-736(MINT-7991393)|glutathione s tranferase tag:?-?(MINT-7991396)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398469|mint:MINT-7991405|imex:IM-15630-21	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991407(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991409(identity)"	-	-	comment:mint	figure legend:f2b|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:1F169FE97D3407F1|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:737-774(MINT-7991412)|glutathione s tranferase tag:?-?(MINT-7991410)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398509|mint:MINT-7991435|imex:IM-15630-23	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991441(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991437(identity)"	-	-	comment:mint	comment:mint|figure legend:f2d f6b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:E36FA3F8F56CE032|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	his tag:?-?(MINT-7991438)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398489|mint:MINT-7991420|imex:IM-15630-22	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991429(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991422(identity)"	-	-	comment:mint	figure legend:f2b|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:1C147296305BA2C4|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:775-810(MINT-7991423)|glutathione s tranferase tag:?-?(MINT-7991426)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398524|mint:MINT-7991447|imex:IM-15630-24	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991449(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991451(identity)"	-	-	comment:mint	figure legend:f2d|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:BF110EC42BD5492E|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:512-550(MINT-7991454)|glutathione s tranferase tag:?-?(MINT-7991452)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398564|mint:MINT-7991477|imex:IM-15630-26	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991479(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991481(identity)"	-	-	comment:mint	figure legend:f2d|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:277969BED0CD960F|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:637-672(MINT-7991484)|glutathione s tranferase tag:?-?(MINT-7991482)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398584|mint:MINT-7991492|imex:IM-15630-27	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991501(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991494(identity)"	-	-	comment:mint	figure legend:f2d|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:5A3DFBDDE60FC498|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:763-800(MINT-7991495)|glutathione s tranferase tag:?-?(MINT-7991498)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398544|mint:MINT-7991462|imex:IM-15630-25	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991471(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991464(identity)"	-	-	comment:mint	figure legend:f2d|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:99B2C6424C51426D|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:610-636(MINT-7991465)|glutathione s tranferase tag:?-?(MINT-7991468)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398604|mint:MINT-7991507|imex:IM-15630-28	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991509(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991511(identity)"	-	-	comment:mint	figure legend:f2d|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:90D01932A49806DF|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:801-838(MINT-7991514)|glutathione s tranferase tag:?-?(MINT-7991512)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398624|mint:MINT-7991522|imex:IM-15630-29	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991531(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991524(identity)"	-	-	comment:mint	figure legend:f2d|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:893AE1BF8EC5D47F|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:839-874(MINT-7991525)|glutathione s tranferase tag:?-?(MINT-7991528)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0049""(filter binding)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398644|mint:MINT-7991636|imex:IM-15630-30	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991638(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991640(identity)"	-	-	comment:mint	comment:domino|comment:mint|figure legend:f7d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:76D956B23E2C2EE3|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	-	binding-associated region:790-800(MINT-7991641)|glutathione s tranferase tag:?-?(MINT-7991644)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398673|mint:MINT-7991540|imex:IM-15630-31	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991542(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991544(identity)"	-	-	comment:mint	figure legend:f3a|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:17.8x10^-9(molar)	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:8C0A67CFA4A26C41|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	binding-associated region:52-272(MINT-7991555)	binding-associated region:763-800(MINT-7991547)|glutathione s tranferase tag:?-?(MINT-7991545)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:P14738	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398697|mint:MINT-7991558|imex:IM-15630-32	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991567(identity)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1|mint:MINT-7991560(identity)"	-	-	comment:mint	figure legend:f3b|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	temp interaction:41.8x10^-9(molar)	2010/08/19	2025/03/31	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	intact-crc:46E78520E6369E35|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	binding-associated region:52-272(MINT-7991574)	binding-associated region:801-838(MINT-7991561)|glutathione s tranferase tag:?-?(MINT-7991564)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398721|mint:MINT-7991577|imex:IM-15630-33	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991580(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991584(identity)"	-	-	comment:mint	figure legend:f3c|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	temp interaction:68.0x10^-9(molar)	2010/08/19	2025/03/25	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:88164A4D72001BD3|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	binding-associated region:52-272(MINT-7991581)	binding-associated region:699-736(MINT-7991587)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Provenza et al. (2010)	pubmed:20875085|imex:IM-15630|mint:MINT-7991081|mint:fj-10-0581.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8398742|mint:MINT-7991594|imex:IM-15630-34	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-7991602(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-7991597(identity)"	-	-	comment:mint	figure legend:f3d|comment:domino|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	temp interaction:103.2x10^-9(molar)	2010/08/19	2025/03/25	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:E57DCAF4317CC721|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	binding-associated region:52-272(MINT-7991603)	binding-associated region:737-774(MINT-7991598)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q306T3	uniprotkb:P05067	intact:EBI-8294101|intact:MINT-7992757	intact:EBI-77613|uniprotkb:P09000|uniprotkb:P78438|uniprotkb:Q13764|uniprotkb:Q13778|uniprotkb:Q13793|intact:EBI-28985182|uniprotkb:Q6GSC0|uniprotkb:Q8WZ99|uniprotkb:Q9UC33|uniprotkb:Q9UCC8|uniprotkb:Q9UCD1|uniprotkb:Q9UQ58|uniprotkb:Q16011|uniprotkb:Q16014|uniprotkb:Q16019|uniprotkb:Q16020|uniprotkb:Q9BT38|uniprotkb:Q9UCA9|uniprotkb:Q9UCB6|uniprotkb:B4DII8|uniprotkb:B2R5V1|uniprotkb:D3DSD1|uniprotkb:D3DSD2|uniprotkb:D3DSD3|ensembl:ENSP00000284981.4	psi-mi:q306t3_9actn(display_long)	"psi-mi:a4_human(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:""Amyloid-beta (A4) precursor protein""(gene name synonym)"	"psi-mi:""MI:0435""(protease assay)"	Yoo et al. (2010)	pubmed:20828565|imex:IM-15619|mint:MINT-7992747|doi:10.1016/j.febslet.2010.08.048	taxid:353796(streptomyces sp. kk565)|taxid:353796(Streptomyces sp. KK565)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8294151|mint:MINT-7992778|imex:IM-15619-2	intact-miscore:0.54	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|interpro:IPR007484(Peptidase M28)|interpro:IPR041756|interpro:IPR045175|mint:Q306T3|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0008235""(metalloexopeptidase activity)|mint:MINT-7992784(identity)"	"interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR020901|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|interpro:IPR036880|interpro:IPR037071|mint:P05067|rcsb pdb:1AAP|rcsb pdb:1AMB|rcsb pdb:1AMC|rcsb pdb:1AML|rcsb pdb:1BA4|rcsb pdb:1BA6|rcsb pdb:1BJB|rcsb pdb:1BJC|rcsb pdb:1BRC|rcsb pdb:1CA0|rcsb pdb:1HZ3|rcsb pdb:1IYT|rcsb pdb:1MWP|rcsb pdb:1OWT|rcsb pdb:1QCM|rcsb pdb:1QWP|rcsb pdb:1QXC|rcsb pdb:1QYT|rcsb pdb:1TAW|rcsb pdb:1TKN|rcsb pdb:1X11|rcsb pdb:1Z0Q|rcsb pdb:1ZE7|rcsb pdb:1ZE9|rcsb pdb:1ZJD|rcsb pdb:2BEG|rcsb pdb:2BP4|rcsb pdb:2FJZ|rcsb pdb:2FK1|rcsb pdb:2FK2|rcsb pdb:2FK3|rcsb pdb:2FKL|rcsb pdb:2FMA|rcsb pdb:2G47|rcsb pdb:2IPU|rcsb pdb:2LFM|rcsb pdb:2LLM|rcsb pdb:2LMN|rcsb pdb:2LMO|rcsb pdb:2LMP|rcsb pdb:2LMQ|rcsb pdb:2LNQ|rcsb pdb:2LOH|rcsb pdb:2LP1|rcsb pdb:2LZ3|rcsb pdb:2LZ4|rcsb pdb:2M4J|rcsb pdb:2M9R|rcsb pdb:2M9S|rcsb pdb:2MGT|rcsb pdb:2MJ1|rcsb pdb:2MPZ|rcsb pdb:2MVX|rcsb pdb:2MXU|rcsb pdb:2NAO|rcsb pdb:2OTK|rcsb pdb:2R0W|rcsb pdb:2WK3|rcsb pdb:2Y29|rcsb pdb:2Y2A|rcsb pdb:2Y3J|rcsb pdb:2Y3K|rcsb pdb:2Y3L|rcsb pdb:3AYU|rcsb pdb:3BAE|rcsb pdb:3BKJ|rcsb pdb:3DXC|rcsb pdb:3DXD|rcsb pdb:3DXE|rcsb pdb:3GCI|rcsb pdb:3IFL|rcsb pdb:3IFN|rcsb pdb:3IFO|rcsb pdb:3IFP|rcsb pdb:3JQ5|rcsb pdb:3JQL|rcsb pdb:3JTI|rcsb pdb:3KTM|rcsb pdb:3L33|rcsb pdb:3L81|rcsb pdb:3MOQ|rcsb pdb:3MXC|rcsb pdb:3MXY|rcsb pdb:3NYJ|rcsb pdb:3NYL|rcsb pdb:3OVJ|rcsb pdb:3OW9|rcsb pdb:3PZZ|rcsb pdb:3Q2X|rcsb pdb:3SV1|rcsb pdb:3U0T|rcsb pdb:3UMH|rcsb pdb:3UMI|rcsb pdb:3UMK|rcsb pdb:4HIX|rcsb pdb:4JFN|rcsb pdb:4M1C|rcsb pdb:4MDR|rcsb pdb:4MVI|rcsb pdb:4MVK|panther:PTHR23103(orthology-group)|rcsb pdb:4MVL|rcsb pdb:4NGE|rcsb pdb:4OJF|rcsb pdb:4ONF|rcsb pdb:4ONG|rcsb pdb:4PQD|rcsb pdb:4PWQ|rcsb pdb:4XXD|rcsb pdb:5AEF|rcsb pdb:5AM8|rcsb pdb:5AMB|rcsb pdb:5BUO|rcsb pdb:5C67|rcsb pdb:5CSZ|rcsb pdb:5HOW|rcsb pdb:5HOX|rcsb pdb:5HOY|rcsb pdb:5KK3|rcsb pdb:5LFY|rcsb pdb:5LV0|rcsb pdb:5MY4|efo:""Orphanet:100006""|efo:""Orphanet:1020""|efo:""Orphanet:324703""|efo:""Orphanet:324708""|efo:""Orphanet:324713""|efo:""Orphanet:324718""|efo:""Orphanet:324723""|rcsb pdb:5MYO|rcsb pdb:5MYX|rcsb pdb:5ONP|rcsb pdb:5ONQ|rcsb pdb:5OQV|rcsb pdb:5TXD|rcsb pdb:5VOS|rcsb pdb:5VZY|rcsb pdb:5W3P|rcsb pdb:6CO3|rcsb pdb:6GFI|rcsb pdb:6ITU|rcsb pdb:6IYC|rcsb pdb:6NB9|rcsb pdb:6O4J|rcsb pdb:6OC9|rcsb pdb:6OIZ|rcsb pdb:6RHY|rcsb pdb:6SHS|rcsb pdb:6SZF|rcsb pdb:6TI5|rcsb pdb:6TI6|rcsb pdb:6TI7|rcsb pdb:6W0O|rcsb pdb:6WXM|rcsb pdb:6XOV|rcsb pdb:6YHF|rcsb pdb:6YHI|rcsb pdb:6YHO|rcsb pdb:6YHP|rcsb pdb:6YHX|rcsb pdb:7B3J|rcsb pdb:7B3K|rcsb pdb:7E6P|rcsb pdb:7F29|rcsb pdb:7JXN|rcsb pdb:7JXO|rcsb pdb:7O1Q|rcsb pdb:7OW1|rcsb pdb:7OXN|rcsb pdb:7Q4B|rcsb pdb:7Q4M|rcsb pdb:7RTZ|rcsb pdb:7U4P|rcsb pdb:7WFY|rcsb pdb:7WVY|rcsb pdb:7Y3J|rcsb pdb:7Y8Q|rcsb pdb:8AZS|rcsb pdb:8AZT|rcsb pdb:8B9Q|rcsb pdb:8B9R|rcsb pdb:8BFA|rcsb pdb:8BFB|dip:DIP-574N|rcsb pdb:8BFZ|rcsb pdb:8BG0|rcsb pdb:8C3H|rcsb pdb:8EZD|rcsb pdb:8EZE|rcsb pdb:8FF2|rcsb pdb:8FF3|rcsb pdb:8H8Q|rcsb pdb:8I4O|rcsb pdb:8KEW|rcsb pdb:8KF1|rcsb pdb:8KF3|rcsb pdb:8KF4|rcsb pdb:8KF5|rcsb pdb:8KF6|rcsb pdb:8OL2|rcsb pdb:8OL3|rcsb pdb:8OL5|rcsb pdb:8OL6|rcsb pdb:8OL7|rcsb pdb:8OLG|rcsb pdb:8OLN|rcsb pdb:8OLO|rcsb pdb:8OLQ|rcsb pdb:8OT1|rcsb pdb:8OT3|rcsb pdb:8OT4|rcsb pdb:8OTF|rcsb pdb:8OVK|rcsb pdb:8OVM|rcsb pdb:8OWD|rcsb pdb:8OWE|rcsb pdb:8OWJ|rcsb pdb:8OWK|rcsb pdb:8QN6|rcsb pdb:8QN7|rcsb pdb:8SEJ|rcsb pdb:8SEK|rcsb pdb:8SEL|rcsb pdb:8T82|rcsb pdb:8T89|rcsb pdb:8X52|rcsb pdb:8X53|rcsb pdb:8X54|rcsb pdb:9CZN|rcsb pdb:9CZP|ensembl:ENSG00000142192.22(gene)|ensembl:ENST00000346798.8(transcript)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001967""(suckling behavior)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005641""(nuclear envelope lumen)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006417""(regulation of translation)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006897""(endocytosis)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007155""(cell adhesion)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007409""(axonogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0007611""(learning or memory)|go:""GO:0007612""(learning)|go:""GO:0007617""(mating behavior)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008088""(axo-dendritic transport)|go:""GO:0008201""(heparin binding)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0008542""(visual learning)|go:""GO:0009986""(cell surface)|go:""GO:0010467""(gene expression)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0010971""(positive regulation of G2/M transition of mitotic cell cycle)|go:""GO:0014005""(microglia development)|go:""GO:0016020""(membrane)|go:""GO:0016199""(axon midline choice point recognition)|go:""GO:0016322""(neuron remodeling)|go:""GO:0016358""(dendrite development)|go:""GO:0019899""(enzyme binding)|go:""GO:0030111""(regulation of Wnt signaling pathway)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030546""(signaling receptor activator activity)|go:""GO:0030900""(forebrain development)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031175""(neuron projection development)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031904""(endosome lumen)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035235""(ionotropic glutamate receptor signaling pathway)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043204""(perikaryon)|go:""GO:0043235""(receptor complex)|go:""GO:0045121""(membrane raft)|go:""GO:0045177""(apical part of cell)|go:""GO:0045202""(synapse)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046914""(transition metal ion binding)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048143""(astrocyte activation)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|interpro:IPR013803(Amyloidogenic glycoprotein, amyloid-beta peptide)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048669""(collateral sprouting in absence of injury)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050803""(regulation of synapse structure or activity)|go:""GO:0050808""(synapse organization)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0050890""(cognition)|go:""GO:0051124""(synaptic assembly at neuromuscular junction)|go:""GO:0051233""(spindle midzone)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051425""(PTB domain binding)|go:""GO:0051563""(smooth endoplasmic reticulum calcium ion homeostasis)|go:""GO:0055037""(recycling endosome)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0098815""(modulation of excitatory postsynaptic potential)|go:""GO:0098989""(NMDA selective glutamate receptor signaling pathway)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0180011""(cytosolic mRNA polyadenylation)|go:""GO:1900272""(negative regulation of long-term synaptic potentiation)|go:""GO:1900273""(positive regulation of long-term synaptic potentiation)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905606""(regulation of presynapse assembly)|go:""GO:1905607""(negative regulation of presynapse assembly)|go:""GO:1905908""(positive regulation of amyloid fibril formation)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990535""(neuron projection maintenance)|go:""GO:2000406""(positive regulation of T cell migration)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-114608|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-432720|reactome:R-HSA-444473|reactome:R-HSA-445989|reactome:R-HSA-844456|reactome:R-HSA-879415|reactome:R-HSA-8862803|reactome:R-HSA-8957275|reactome:R-HSA-933542|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-977225|reactome:R-HSA-9837999|refseq:NP_000475.1|refseq:NP_001129488.1|refseq:NP_001129601.1|refseq:NP_001129602.1|refseq:NP_001129603.1|refseq:NP_001191230.1|refseq:NP_001191231.1|refseq:NP_001191232.1|refseq:NP_958816.1|refseq:NP_958817.1|mint:MINT-7992780(identity)"	-	comment:mint	-	figure legend:f2d|comment:mint|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/31	2025/03/05	rogid:0DjqaCed71gVSEpirPUsPlbjYOs353796	rogid:HatR8w8+mNjtjr7s5+bAwaStpmk9606	intact-crc:B726B0E2550A5721|rigid:PuhyNwvzYLyqrRmPqq+QYhH20Zs	false	binding-associated region:39-320(MINT-7992785)	binding-associated region:672-713(MINT-7992781)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:P05067	uniprotkb:Q306T3	intact:EBI-77613|uniprotkb:P09000|uniprotkb:P78438|uniprotkb:Q13764|uniprotkb:Q13778|uniprotkb:Q13793|intact:EBI-28985182|uniprotkb:Q6GSC0|uniprotkb:Q8WZ99|uniprotkb:Q9UC33|uniprotkb:Q9UCC8|uniprotkb:Q9UCD1|uniprotkb:Q9UQ58|uniprotkb:Q16011|uniprotkb:Q16014|uniprotkb:Q16019|uniprotkb:Q16020|uniprotkb:Q9BT38|uniprotkb:Q9UCA9|uniprotkb:Q9UCB6|uniprotkb:B4DII8|uniprotkb:B2R5V1|uniprotkb:D3DSD1|uniprotkb:D3DSD2|uniprotkb:D3DSD3|ensembl:ENSP00000284981.4	intact:EBI-8294101|intact:MINT-7992757	"psi-mi:a4_human(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:""Amyloid-beta (A4) precursor protein""(gene name synonym)"	psi-mi:q306t3_9actn(display_long)	"psi-mi:""MI:0435""(protease assay)"	Yoo et al. (2010)	pubmed:20828565|imex:IM-15619|mint:MINT-7992747|doi:10.1016/j.febslet.2010.08.048	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:353796(streptomyces sp. kk565)|taxid:353796(Streptomyces sp. KK565)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8294113|mint:MINT-7992752|imex:IM-15619-1	intact-miscore:0.54	-	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR020901|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|interpro:IPR036880|interpro:IPR037071|mint:P05067|rcsb pdb:1AAP|rcsb pdb:1AMB|rcsb pdb:1AMC|rcsb pdb:1AML|rcsb pdb:1BA4|rcsb pdb:1BA6|rcsb pdb:1BJB|rcsb pdb:1BJC|rcsb pdb:1BRC|rcsb pdb:1CA0|rcsb pdb:1HZ3|rcsb pdb:1IYT|rcsb pdb:1MWP|rcsb pdb:1OWT|rcsb pdb:1QCM|rcsb pdb:1QWP|rcsb pdb:1QXC|rcsb pdb:1QYT|rcsb pdb:1TAW|rcsb pdb:1TKN|rcsb pdb:1X11|rcsb pdb:1Z0Q|rcsb pdb:1ZE7|rcsb pdb:1ZE9|rcsb pdb:1ZJD|rcsb pdb:2BEG|rcsb pdb:2BP4|rcsb pdb:2FJZ|rcsb pdb:2FK1|rcsb pdb:2FK2|rcsb pdb:2FK3|rcsb pdb:2FKL|rcsb pdb:2FMA|rcsb pdb:2G47|rcsb pdb:2IPU|rcsb pdb:2LFM|rcsb pdb:2LLM|rcsb pdb:2LMN|rcsb pdb:2LMO|rcsb pdb:2LMP|rcsb pdb:2LMQ|rcsb pdb:2LNQ|rcsb pdb:2LOH|rcsb pdb:2LP1|rcsb pdb:2LZ3|rcsb pdb:2LZ4|rcsb pdb:2M4J|rcsb pdb:2M9R|rcsb pdb:2M9S|rcsb pdb:2MGT|rcsb pdb:2MJ1|rcsb pdb:2MPZ|rcsb pdb:2MVX|rcsb pdb:2MXU|rcsb pdb:2NAO|rcsb pdb:2OTK|rcsb pdb:2R0W|rcsb pdb:2WK3|rcsb pdb:2Y29|rcsb pdb:2Y2A|rcsb pdb:2Y3J|rcsb pdb:2Y3K|rcsb pdb:2Y3L|rcsb pdb:3AYU|rcsb pdb:3BAE|rcsb pdb:3BKJ|rcsb pdb:3DXC|rcsb pdb:3DXD|rcsb pdb:3DXE|rcsb pdb:3GCI|rcsb pdb:3IFL|rcsb pdb:3IFN|rcsb pdb:3IFO|rcsb pdb:3IFP|rcsb pdb:3JQ5|rcsb pdb:3JQL|rcsb pdb:3JTI|rcsb pdb:3KTM|rcsb pdb:3L33|rcsb pdb:3L81|rcsb pdb:3MOQ|rcsb pdb:3MXC|rcsb pdb:3MXY|rcsb pdb:3NYJ|rcsb pdb:3NYL|rcsb pdb:3OVJ|rcsb pdb:3OW9|rcsb pdb:3PZZ|rcsb pdb:3Q2X|rcsb pdb:3SV1|rcsb pdb:3U0T|rcsb pdb:3UMH|rcsb pdb:3UMI|rcsb pdb:3UMK|rcsb pdb:4HIX|rcsb pdb:4JFN|rcsb pdb:4M1C|rcsb pdb:4MDR|rcsb pdb:4MVI|rcsb pdb:4MVK|panther:PTHR23103(orthology-group)|rcsb pdb:4MVL|rcsb pdb:4NGE|rcsb pdb:4OJF|rcsb pdb:4ONF|rcsb pdb:4ONG|rcsb pdb:4PQD|rcsb pdb:4PWQ|rcsb pdb:4XXD|rcsb pdb:5AEF|rcsb pdb:5AM8|rcsb pdb:5AMB|rcsb pdb:5BUO|rcsb pdb:5C67|rcsb pdb:5CSZ|rcsb pdb:5HOW|rcsb pdb:5HOX|rcsb pdb:5HOY|rcsb pdb:5KK3|rcsb pdb:5LFY|rcsb pdb:5LV0|rcsb pdb:5MY4|efo:""Orphanet:100006""|efo:""Orphanet:1020""|efo:""Orphanet:324703""|efo:""Orphanet:324708""|efo:""Orphanet:324713""|efo:""Orphanet:324718""|efo:""Orphanet:324723""|rcsb pdb:5MYO|rcsb pdb:5MYX|rcsb pdb:5ONP|rcsb pdb:5ONQ|rcsb pdb:5OQV|rcsb pdb:5TXD|rcsb pdb:5VOS|rcsb pdb:5VZY|rcsb pdb:5W3P|rcsb pdb:6CO3|rcsb pdb:6GFI|rcsb pdb:6ITU|rcsb pdb:6IYC|rcsb pdb:6NB9|rcsb pdb:6O4J|rcsb pdb:6OC9|rcsb pdb:6OIZ|rcsb pdb:6RHY|rcsb pdb:6SHS|rcsb pdb:6SZF|rcsb pdb:6TI5|rcsb pdb:6TI6|rcsb pdb:6TI7|rcsb pdb:6W0O|rcsb pdb:6WXM|rcsb pdb:6XOV|rcsb pdb:6YHF|rcsb pdb:6YHI|rcsb pdb:6YHO|rcsb pdb:6YHP|rcsb pdb:6YHX|rcsb pdb:7B3J|rcsb pdb:7B3K|rcsb pdb:7E6P|rcsb pdb:7F29|rcsb pdb:7JXN|rcsb pdb:7JXO|rcsb pdb:7O1Q|rcsb pdb:7OW1|rcsb pdb:7OXN|rcsb pdb:7Q4B|rcsb pdb:7Q4M|rcsb pdb:7RTZ|rcsb pdb:7U4P|rcsb pdb:7WFY|rcsb pdb:7WVY|rcsb pdb:7Y3J|rcsb pdb:7Y8Q|rcsb pdb:8AZS|rcsb pdb:8AZT|rcsb pdb:8B9Q|rcsb pdb:8B9R|rcsb pdb:8BFA|rcsb pdb:8BFB|dip:DIP-574N|rcsb pdb:8BFZ|rcsb pdb:8BG0|rcsb pdb:8C3H|rcsb pdb:8EZD|rcsb pdb:8EZE|rcsb pdb:8FF2|rcsb pdb:8FF3|rcsb pdb:8H8Q|rcsb pdb:8I4O|rcsb pdb:8KEW|rcsb pdb:8KF1|rcsb pdb:8KF3|rcsb pdb:8KF4|rcsb pdb:8KF5|rcsb pdb:8KF6|rcsb pdb:8OL2|rcsb pdb:8OL3|rcsb pdb:8OL5|rcsb pdb:8OL6|rcsb pdb:8OL7|rcsb pdb:8OLG|rcsb pdb:8OLN|rcsb pdb:8OLO|rcsb pdb:8OLQ|rcsb pdb:8OT1|rcsb pdb:8OT3|rcsb pdb:8OT4|rcsb pdb:8OTF|rcsb pdb:8OVK|rcsb pdb:8OVM|rcsb pdb:8OWD|rcsb pdb:8OWE|rcsb pdb:8OWJ|rcsb pdb:8OWK|rcsb pdb:8QN6|rcsb pdb:8QN7|rcsb pdb:8SEJ|rcsb pdb:8SEK|rcsb pdb:8SEL|rcsb pdb:8T82|rcsb pdb:8T89|rcsb pdb:8X52|rcsb pdb:8X53|rcsb pdb:8X54|rcsb pdb:9CZN|rcsb pdb:9CZP|ensembl:ENSG00000142192.22(gene)|ensembl:ENST00000346798.8(transcript)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001967""(suckling behavior)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005641""(nuclear envelope lumen)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006417""(regulation of translation)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006897""(endocytosis)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007155""(cell adhesion)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007409""(axonogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0007611""(learning or memory)|go:""GO:0007612""(learning)|go:""GO:0007617""(mating behavior)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008088""(axo-dendritic transport)|go:""GO:0008201""(heparin binding)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0008542""(visual learning)|go:""GO:0009986""(cell surface)|go:""GO:0010467""(gene expression)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0010971""(positive regulation of G2/M transition of mitotic cell cycle)|go:""GO:0014005""(microglia development)|go:""GO:0016020""(membrane)|go:""GO:0016199""(axon midline choice point recognition)|go:""GO:0016322""(neuron remodeling)|go:""GO:0016358""(dendrite development)|go:""GO:0019899""(enzyme binding)|go:""GO:0030111""(regulation of Wnt signaling pathway)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030546""(signaling receptor activator activity)|go:""GO:0030900""(forebrain development)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031175""(neuron projection development)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031904""(endosome lumen)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035235""(ionotropic glutamate receptor signaling pathway)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043204""(perikaryon)|go:""GO:0043235""(receptor complex)|go:""GO:0045121""(membrane raft)|go:""GO:0045177""(apical part of cell)|go:""GO:0045202""(synapse)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046914""(transition metal ion binding)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048143""(astrocyte activation)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|interpro:IPR013803(Amyloidogenic glycoprotein, amyloid-beta peptide)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048669""(collateral sprouting in absence of injury)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050803""(regulation of synapse structure or activity)|go:""GO:0050808""(synapse organization)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0050890""(cognition)|go:""GO:0051124""(synaptic assembly at neuromuscular junction)|go:""GO:0051233""(spindle midzone)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051425""(PTB domain binding)|go:""GO:0051563""(smooth endoplasmic reticulum calcium ion homeostasis)|go:""GO:0055037""(recycling endosome)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0098815""(modulation of excitatory postsynaptic potential)|go:""GO:0098989""(NMDA selective glutamate receptor signaling pathway)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0180011""(cytosolic mRNA polyadenylation)|go:""GO:1900272""(negative regulation of long-term synaptic potentiation)|go:""GO:1900273""(positive regulation of long-term synaptic potentiation)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905606""(regulation of presynapse assembly)|go:""GO:1905607""(negative regulation of presynapse assembly)|go:""GO:1905908""(positive regulation of amyloid fibril formation)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990535""(neuron projection maintenance)|go:""GO:2000406""(positive regulation of T cell migration)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-114608|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-432720|reactome:R-HSA-444473|reactome:R-HSA-445989|reactome:R-HSA-844456|reactome:R-HSA-879415|reactome:R-HSA-8862803|reactome:R-HSA-8957275|reactome:R-HSA-933542|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-977225|reactome:R-HSA-9837999|refseq:NP_000475.1|refseq:NP_001129488.1|refseq:NP_001129601.1|refseq:NP_001129602.1|refseq:NP_001129603.1|refseq:NP_001191230.1|refseq:NP_001191231.1|refseq:NP_001191232.1|refseq:NP_958816.1|refseq:NP_958817.1|mint:MINT-7992754(identity)"	"interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|interpro:IPR007484(Peptidase M28)|interpro:IPR041756|interpro:IPR045175|mint:Q306T3|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0008235""(metalloexopeptidase activity)|mint:MINT-7992767(identity)"	-	-	comment:mint	figure legend:f2c|comment:mint|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/31	2025/03/05	rogid:HatR8w8+mNjtjr7s5+bAwaStpmk9606	rogid:0DjqaCed71gVSEpirPUsPlbjYOs353796	intact-crc:6DF00C3AE93F8ECB|rigid:PuhyNwvzYLyqrRmPqq+QYhH20Zs	false	binding-associated region:672-711(MINT-7992775)	binding-associated region:39-320(MINT-7992771)	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05067	uniprotkb:Q306T3	intact:EBI-77613|uniprotkb:P09000|uniprotkb:P78438|uniprotkb:Q13764|uniprotkb:Q13778|uniprotkb:Q13793|intact:EBI-28985182|uniprotkb:Q6GSC0|uniprotkb:Q8WZ99|uniprotkb:Q9UC33|uniprotkb:Q9UCC8|uniprotkb:Q9UCD1|uniprotkb:Q9UQ58|uniprotkb:Q16011|uniprotkb:Q16014|uniprotkb:Q16019|uniprotkb:Q16020|uniprotkb:Q9BT38|uniprotkb:Q9UCA9|uniprotkb:Q9UCB6|uniprotkb:B4DII8|uniprotkb:B2R5V1|uniprotkb:D3DSD1|uniprotkb:D3DSD2|uniprotkb:D3DSD3|ensembl:ENSP00000284981.4	intact:EBI-8294101|intact:MINT-7992757	"psi-mi:a4_human(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:""Amyloid-beta (A4) precursor protein""(gene name synonym)"	psi-mi:q306t3_9actn(display_long)	"psi-mi:""MI:0435""(protease assay)"	Yoo et al. (2010)	pubmed:20828565|imex:IM-15619|mint:MINT-7992747|doi:10.1016/j.febslet.2010.08.048	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:353796(streptomyces sp. kk565)|taxid:353796(Streptomyces sp. KK565)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8294168|mint:MINT-7992796|imex:IM-15619-3	intact-miscore:0.54	-	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR020901|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|interpro:IPR036880|interpro:IPR037071|mint:P05067|rcsb pdb:1AAP|rcsb pdb:1AMB|rcsb pdb:1AMC|rcsb pdb:1AML|rcsb pdb:1BA4|rcsb pdb:1BA6|rcsb pdb:1BJB|rcsb pdb:1BJC|rcsb pdb:1BRC|rcsb pdb:1CA0|rcsb pdb:1HZ3|rcsb pdb:1IYT|rcsb pdb:1MWP|rcsb pdb:1OWT|rcsb pdb:1QCM|rcsb pdb:1QWP|rcsb pdb:1QXC|rcsb pdb:1QYT|rcsb pdb:1TAW|rcsb pdb:1TKN|rcsb pdb:1X11|rcsb pdb:1Z0Q|rcsb pdb:1ZE7|rcsb pdb:1ZE9|rcsb pdb:1ZJD|rcsb pdb:2BEG|rcsb pdb:2BP4|rcsb pdb:2FJZ|rcsb pdb:2FK1|rcsb pdb:2FK2|rcsb pdb:2FK3|rcsb pdb:2FKL|rcsb pdb:2FMA|rcsb pdb:2G47|rcsb pdb:2IPU|rcsb pdb:2LFM|rcsb pdb:2LLM|rcsb pdb:2LMN|rcsb pdb:2LMO|rcsb pdb:2LMP|rcsb pdb:2LMQ|rcsb pdb:2LNQ|rcsb pdb:2LOH|rcsb pdb:2LP1|rcsb pdb:2LZ3|rcsb pdb:2LZ4|rcsb pdb:2M4J|rcsb pdb:2M9R|rcsb pdb:2M9S|rcsb pdb:2MGT|rcsb pdb:2MJ1|rcsb pdb:2MPZ|rcsb pdb:2MVX|rcsb pdb:2MXU|rcsb pdb:2NAO|rcsb pdb:2OTK|rcsb pdb:2R0W|rcsb pdb:2WK3|rcsb pdb:2Y29|rcsb pdb:2Y2A|rcsb pdb:2Y3J|rcsb pdb:2Y3K|rcsb pdb:2Y3L|rcsb pdb:3AYU|rcsb pdb:3BAE|rcsb pdb:3BKJ|rcsb pdb:3DXC|rcsb pdb:3DXD|rcsb pdb:3DXE|rcsb pdb:3GCI|rcsb pdb:3IFL|rcsb pdb:3IFN|rcsb pdb:3IFO|rcsb pdb:3IFP|rcsb pdb:3JQ5|rcsb pdb:3JQL|rcsb pdb:3JTI|rcsb pdb:3KTM|rcsb pdb:3L33|rcsb pdb:3L81|rcsb pdb:3MOQ|rcsb pdb:3MXC|rcsb pdb:3MXY|rcsb pdb:3NYJ|rcsb pdb:3NYL|rcsb pdb:3OVJ|rcsb pdb:3OW9|rcsb pdb:3PZZ|rcsb pdb:3Q2X|rcsb pdb:3SV1|rcsb pdb:3U0T|rcsb pdb:3UMH|rcsb pdb:3UMI|rcsb pdb:3UMK|rcsb pdb:4HIX|rcsb pdb:4JFN|rcsb pdb:4M1C|rcsb pdb:4MDR|rcsb pdb:4MVI|rcsb pdb:4MVK|panther:PTHR23103(orthology-group)|rcsb pdb:4MVL|rcsb pdb:4NGE|rcsb pdb:4OJF|rcsb pdb:4ONF|rcsb pdb:4ONG|rcsb pdb:4PQD|rcsb pdb:4PWQ|rcsb pdb:4XXD|rcsb pdb:5AEF|rcsb pdb:5AM8|rcsb pdb:5AMB|rcsb pdb:5BUO|rcsb pdb:5C67|rcsb pdb:5CSZ|rcsb pdb:5HOW|rcsb pdb:5HOX|rcsb pdb:5HOY|rcsb pdb:5KK3|rcsb pdb:5LFY|rcsb pdb:5LV0|rcsb pdb:5MY4|efo:""Orphanet:100006""|efo:""Orphanet:1020""|efo:""Orphanet:324703""|efo:""Orphanet:324708""|efo:""Orphanet:324713""|efo:""Orphanet:324718""|efo:""Orphanet:324723""|rcsb pdb:5MYO|rcsb pdb:5MYX|rcsb pdb:5ONP|rcsb pdb:5ONQ|rcsb pdb:5OQV|rcsb pdb:5TXD|rcsb pdb:5VOS|rcsb pdb:5VZY|rcsb pdb:5W3P|rcsb pdb:6CO3|rcsb pdb:6GFI|rcsb pdb:6ITU|rcsb pdb:6IYC|rcsb pdb:6NB9|rcsb pdb:6O4J|rcsb pdb:6OC9|rcsb pdb:6OIZ|rcsb pdb:6RHY|rcsb pdb:6SHS|rcsb pdb:6SZF|rcsb pdb:6TI5|rcsb pdb:6TI6|rcsb pdb:6TI7|rcsb pdb:6W0O|rcsb pdb:6WXM|rcsb pdb:6XOV|rcsb pdb:6YHF|rcsb pdb:6YHI|rcsb pdb:6YHO|rcsb pdb:6YHP|rcsb pdb:6YHX|rcsb pdb:7B3J|rcsb pdb:7B3K|rcsb pdb:7E6P|rcsb pdb:7F29|rcsb pdb:7JXN|rcsb pdb:7JXO|rcsb pdb:7O1Q|rcsb pdb:7OW1|rcsb pdb:7OXN|rcsb pdb:7Q4B|rcsb pdb:7Q4M|rcsb pdb:7RTZ|rcsb pdb:7U4P|rcsb pdb:7WFY|rcsb pdb:7WVY|rcsb pdb:7Y3J|rcsb pdb:7Y8Q|rcsb pdb:8AZS|rcsb pdb:8AZT|rcsb pdb:8B9Q|rcsb pdb:8B9R|rcsb pdb:8BFA|rcsb pdb:8BFB|dip:DIP-574N|rcsb pdb:8BFZ|rcsb pdb:8BG0|rcsb pdb:8C3H|rcsb pdb:8EZD|rcsb pdb:8EZE|rcsb pdb:8FF2|rcsb pdb:8FF3|rcsb pdb:8H8Q|rcsb pdb:8I4O|rcsb pdb:8KEW|rcsb pdb:8KF1|rcsb pdb:8KF3|rcsb pdb:8KF4|rcsb pdb:8KF5|rcsb pdb:8KF6|rcsb pdb:8OL2|rcsb pdb:8OL3|rcsb pdb:8OL5|rcsb pdb:8OL6|rcsb pdb:8OL7|rcsb pdb:8OLG|rcsb pdb:8OLN|rcsb pdb:8OLO|rcsb pdb:8OLQ|rcsb pdb:8OT1|rcsb pdb:8OT3|rcsb pdb:8OT4|rcsb pdb:8OTF|rcsb pdb:8OVK|rcsb pdb:8OVM|rcsb pdb:8OWD|rcsb pdb:8OWE|rcsb pdb:8OWJ|rcsb pdb:8OWK|rcsb pdb:8QN6|rcsb pdb:8QN7|rcsb pdb:8SEJ|rcsb pdb:8SEK|rcsb pdb:8SEL|rcsb pdb:8T82|rcsb pdb:8T89|rcsb pdb:8X52|rcsb pdb:8X53|rcsb pdb:8X54|rcsb pdb:9CZN|rcsb pdb:9CZP|ensembl:ENSG00000142192.22(gene)|ensembl:ENST00000346798.8(transcript)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001967""(suckling behavior)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005641""(nuclear envelope lumen)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006417""(regulation of translation)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006897""(endocytosis)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007155""(cell adhesion)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007409""(axonogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0007611""(learning or memory)|go:""GO:0007612""(learning)|go:""GO:0007617""(mating behavior)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008088""(axo-dendritic transport)|go:""GO:0008201""(heparin binding)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0008542""(visual learning)|go:""GO:0009986""(cell surface)|go:""GO:0010467""(gene expression)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0010971""(positive regulation of G2/M transition of mitotic cell cycle)|go:""GO:0014005""(microglia development)|go:""GO:0016020""(membrane)|go:""GO:0016199""(axon midline choice point recognition)|go:""GO:0016322""(neuron remodeling)|go:""GO:0016358""(dendrite development)|go:""GO:0019899""(enzyme binding)|go:""GO:0030111""(regulation of Wnt signaling pathway)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030546""(signaling receptor activator activity)|go:""GO:0030900""(forebrain development)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031175""(neuron projection development)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031904""(endosome lumen)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035235""(ionotropic glutamate receptor signaling pathway)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043204""(perikaryon)|go:""GO:0043235""(receptor complex)|go:""GO:0045121""(membrane raft)|go:""GO:0045177""(apical part of cell)|go:""GO:0045202""(synapse)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046914""(transition metal ion binding)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048143""(astrocyte activation)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|interpro:IPR013803(Amyloidogenic glycoprotein, amyloid-beta peptide)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048669""(collateral sprouting in absence of injury)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050803""(regulation of synapse structure or activity)|go:""GO:0050808""(synapse organization)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0050890""(cognition)|go:""GO:0051124""(synaptic assembly at neuromuscular junction)|go:""GO:0051233""(spindle midzone)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051425""(PTB domain binding)|go:""GO:0051563""(smooth endoplasmic reticulum calcium ion homeostasis)|go:""GO:0055037""(recycling endosome)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0098815""(modulation of excitatory postsynaptic potential)|go:""GO:0098989""(NMDA selective glutamate receptor signaling pathway)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0180011""(cytosolic mRNA polyadenylation)|go:""GO:1900272""(negative regulation of long-term synaptic potentiation)|go:""GO:1900273""(positive regulation of long-term synaptic potentiation)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905606""(regulation of presynapse assembly)|go:""GO:1905607""(negative regulation of presynapse assembly)|go:""GO:1905908""(positive regulation of amyloid fibril formation)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990535""(neuron projection maintenance)|go:""GO:2000406""(positive regulation of T cell migration)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-114608|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-432720|reactome:R-HSA-444473|reactome:R-HSA-445989|reactome:R-HSA-844456|reactome:R-HSA-879415|reactome:R-HSA-8862803|reactome:R-HSA-8957275|reactome:R-HSA-933542|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-977225|reactome:R-HSA-9837999|refseq:NP_000475.1|refseq:NP_001129488.1|refseq:NP_001129601.1|refseq:NP_001129602.1|refseq:NP_001129603.1|refseq:NP_001191230.1|refseq:NP_001191231.1|refseq:NP_001191232.1|refseq:NP_958816.1|refseq:NP_958817.1|mint:MINT-7992802(identity)"	"interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|interpro:IPR007484(Peptidase M28)|interpro:IPR041756|interpro:IPR045175|mint:Q306T3|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0008235""(metalloexopeptidase activity)|mint:MINT-7992798(identity)"	-	-	comment:mint	figure legend:f3a|comment:mint|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/08/31	2025/03/05	rogid:HatR8w8+mNjtjr7s5+bAwaStpmk9606	rogid:0DjqaCed71gVSEpirPUsPlbjYOs353796	intact-crc:8133C6C88255F4D1|rigid:PuhyNwvzYLyqrRmPqq+QYhH20Zs	false	binding-associated region:672-713(MINT-7992803)	binding-associated region:39-320(MINT-7992799)	-	-	"psi-mi:""MI:0072""(monoclonal antibody western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05067	uniprotkb:P01556	intact:EBI-77613|uniprotkb:P09000|uniprotkb:P78438|uniprotkb:Q13764|uniprotkb:Q13778|uniprotkb:Q13793|intact:EBI-28985182|uniprotkb:Q6GSC0|uniprotkb:Q8WZ99|uniprotkb:Q9UC33|uniprotkb:Q9UCC8|uniprotkb:Q9UCD1|uniprotkb:Q9UQ58|uniprotkb:Q16011|uniprotkb:Q16014|uniprotkb:Q16019|uniprotkb:Q16020|uniprotkb:Q9BT38|uniprotkb:Q9UCA9|uniprotkb:Q9UCB6|uniprotkb:B4DII8|uniprotkb:B2R5V1|uniprotkb:D3DSD1|uniprotkb:D3DSD2|uniprotkb:D3DSD3|ensembl:ENSP00000284981.4	intact:EBI-1038383|uniprotkb:Q9JQ02	"psi-mi:a4_human(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:""Amyloid-beta (A4) precursor protein""(gene name synonym)"	psi-mi:chtb_vibch(display_long)|uniprotkb:ctxB(gene name)|psi-mi:ctxB(display_short)|uniprotkb:toxB(gene name synonym)|uniprotkb:VC_1456(locus name)|uniprotkb:Cholera enterotoxin B chain(gene name synonym)|uniprotkb:Cholera enterotoxin gamma chain(gene name synonym)|uniprotkb:Choleragenoid(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Singh et al. (2010)	pubmed:20828568|imex:IM-15846|mint:MINT-7993285|doi:10.1016/j.febslet.2010.08.050	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:243277(vibch)|taxid:243277(Vibrio cholerae)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8296391|mint:MINT-7993537|imex:IM-15846-1	intact-miscore:0.27	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR020901|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|interpro:IPR036880|interpro:IPR037071|mint:P05067|rcsb pdb:1AAP|rcsb pdb:1AMB|rcsb pdb:1AMC|rcsb pdb:1AML|rcsb pdb:1BA4|rcsb pdb:1BA6|rcsb pdb:1BJB|rcsb pdb:1BJC|rcsb pdb:1BRC|rcsb pdb:1CA0|rcsb pdb:1HZ3|rcsb pdb:1IYT|rcsb pdb:1MWP|rcsb pdb:1OWT|rcsb pdb:1QCM|rcsb pdb:1QWP|rcsb pdb:1QXC|rcsb pdb:1QYT|rcsb pdb:1TAW|rcsb pdb:1TKN|rcsb pdb:1X11|rcsb pdb:1Z0Q|rcsb pdb:1ZE7|rcsb pdb:1ZE9|rcsb pdb:1ZJD|rcsb pdb:2BEG|rcsb pdb:2BP4|rcsb pdb:2FJZ|rcsb pdb:2FK1|rcsb pdb:2FK2|rcsb pdb:2FK3|rcsb pdb:2FKL|rcsb pdb:2FMA|rcsb pdb:2G47|rcsb pdb:2IPU|rcsb pdb:2LFM|rcsb pdb:2LLM|rcsb pdb:2LMN|rcsb pdb:2LMO|rcsb pdb:2LMP|rcsb pdb:2LMQ|rcsb pdb:2LNQ|rcsb pdb:2LOH|rcsb pdb:2LP1|rcsb pdb:2LZ3|rcsb pdb:2LZ4|rcsb pdb:2M4J|rcsb pdb:2M9R|rcsb pdb:2M9S|rcsb pdb:2MGT|rcsb pdb:2MJ1|rcsb pdb:2MPZ|rcsb pdb:2MVX|rcsb pdb:2MXU|rcsb pdb:2NAO|rcsb pdb:2OTK|rcsb pdb:2R0W|rcsb pdb:2WK3|rcsb pdb:2Y29|rcsb pdb:2Y2A|rcsb pdb:2Y3J|rcsb pdb:2Y3K|rcsb pdb:2Y3L|rcsb pdb:3AYU|rcsb pdb:3BAE|rcsb pdb:3BKJ|rcsb pdb:3DXC|rcsb pdb:3DXD|rcsb pdb:3DXE|rcsb pdb:3GCI|rcsb pdb:3IFL|rcsb pdb:3IFN|rcsb pdb:3IFO|rcsb pdb:3IFP|rcsb pdb:3JQ5|rcsb pdb:3JQL|rcsb pdb:3JTI|rcsb pdb:3KTM|rcsb pdb:3L33|rcsb pdb:3L81|rcsb pdb:3MOQ|rcsb pdb:3MXC|rcsb pdb:3MXY|rcsb pdb:3NYJ|rcsb pdb:3NYL|rcsb pdb:3OVJ|rcsb pdb:3OW9|rcsb pdb:3PZZ|rcsb pdb:3Q2X|rcsb pdb:3SV1|rcsb pdb:3U0T|rcsb pdb:3UMH|rcsb pdb:3UMI|rcsb pdb:3UMK|rcsb pdb:4HIX|rcsb pdb:4JFN|rcsb pdb:4M1C|rcsb pdb:4MDR|rcsb pdb:4MVI|rcsb pdb:4MVK|panther:PTHR23103(orthology-group)|rcsb pdb:4MVL|rcsb pdb:4NGE|rcsb pdb:4OJF|rcsb pdb:4ONF|rcsb pdb:4ONG|rcsb pdb:4PQD|rcsb pdb:4PWQ|rcsb pdb:4XXD|rcsb pdb:5AEF|rcsb pdb:5AM8|rcsb pdb:5AMB|rcsb pdb:5BUO|rcsb pdb:5C67|rcsb pdb:5CSZ|rcsb pdb:5HOW|rcsb pdb:5HOX|rcsb pdb:5HOY|rcsb pdb:5KK3|rcsb pdb:5LFY|rcsb pdb:5LV0|rcsb pdb:5MY4|efo:""Orphanet:100006""|efo:""Orphanet:1020""|efo:""Orphanet:324703""|efo:""Orphanet:324708""|efo:""Orphanet:324713""|efo:""Orphanet:324718""|efo:""Orphanet:324723""|rcsb pdb:5MYO|rcsb pdb:5MYX|rcsb pdb:5ONP|rcsb pdb:5ONQ|rcsb pdb:5OQV|rcsb pdb:5TXD|rcsb pdb:5VOS|rcsb pdb:5VZY|rcsb pdb:5W3P|rcsb pdb:6CO3|rcsb pdb:6GFI|rcsb pdb:6ITU|rcsb pdb:6IYC|rcsb pdb:6NB9|rcsb pdb:6O4J|rcsb pdb:6OC9|rcsb pdb:6OIZ|rcsb pdb:6RHY|rcsb pdb:6SHS|rcsb pdb:6SZF|rcsb pdb:6TI5|rcsb pdb:6TI6|rcsb pdb:6TI7|rcsb pdb:6W0O|rcsb pdb:6WXM|rcsb pdb:6XOV|rcsb pdb:6YHF|rcsb pdb:6YHI|rcsb pdb:6YHO|rcsb pdb:6YHP|rcsb pdb:6YHX|rcsb pdb:7B3J|rcsb pdb:7B3K|rcsb pdb:7E6P|rcsb pdb:7F29|rcsb pdb:7JXN|rcsb pdb:7JXO|rcsb pdb:7O1Q|rcsb pdb:7OW1|rcsb pdb:7OXN|rcsb pdb:7Q4B|rcsb pdb:7Q4M|rcsb pdb:7RTZ|rcsb pdb:7U4P|rcsb pdb:7WFY|rcsb pdb:7WVY|rcsb pdb:7Y3J|rcsb pdb:7Y8Q|rcsb pdb:8AZS|rcsb pdb:8AZT|rcsb pdb:8B9Q|rcsb pdb:8B9R|rcsb pdb:8BFA|rcsb pdb:8BFB|dip:DIP-574N|rcsb pdb:8BFZ|rcsb pdb:8BG0|rcsb pdb:8C3H|rcsb pdb:8EZD|rcsb pdb:8EZE|rcsb pdb:8FF2|rcsb pdb:8FF3|rcsb pdb:8H8Q|rcsb pdb:8I4O|rcsb pdb:8KEW|rcsb pdb:8KF1|rcsb pdb:8KF3|rcsb pdb:8KF4|rcsb pdb:8KF5|rcsb pdb:8KF6|rcsb pdb:8OL2|rcsb pdb:8OL3|rcsb pdb:8OL5|rcsb pdb:8OL6|rcsb pdb:8OL7|rcsb pdb:8OLG|rcsb pdb:8OLN|rcsb pdb:8OLO|rcsb pdb:8OLQ|rcsb pdb:8OT1|rcsb pdb:8OT3|rcsb pdb:8OT4|rcsb pdb:8OTF|rcsb pdb:8OVK|rcsb pdb:8OVM|rcsb pdb:8OWD|rcsb pdb:8OWE|rcsb pdb:8OWJ|rcsb pdb:8OWK|rcsb pdb:8QN6|rcsb pdb:8QN7|rcsb pdb:8SEJ|rcsb pdb:8SEK|rcsb pdb:8SEL|rcsb pdb:8T82|rcsb pdb:8T89|rcsb pdb:8X52|rcsb pdb:8X53|rcsb pdb:8X54|rcsb pdb:9CZN|rcsb pdb:9CZP|ensembl:ENSG00000142192.22(gene)|ensembl:ENST00000346798.8(transcript)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001967""(suckling behavior)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005641""(nuclear envelope lumen)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006417""(regulation of translation)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006897""(endocytosis)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007155""(cell adhesion)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007409""(axonogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0007611""(learning or memory)|go:""GO:0007612""(learning)|go:""GO:0007617""(mating behavior)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008088""(axo-dendritic transport)|go:""GO:0008201""(heparin binding)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0008542""(visual learning)|go:""GO:0009986""(cell surface)|go:""GO:0010467""(gene expression)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0010971""(positive regulation of G2/M transition of mitotic cell cycle)|go:""GO:0014005""(microglia development)|go:""GO:0016020""(membrane)|go:""GO:0016199""(axon midline choice point recognition)|go:""GO:0016322""(neuron remodeling)|go:""GO:0016358""(dendrite development)|go:""GO:0019899""(enzyme binding)|go:""GO:0030111""(regulation of Wnt signaling pathway)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030546""(signaling receptor activator activity)|go:""GO:0030900""(forebrain development)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031175""(neuron projection development)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031904""(endosome lumen)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035235""(ionotropic glutamate receptor signaling pathway)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043204""(perikaryon)|go:""GO:0043235""(receptor complex)|go:""GO:0045121""(membrane raft)|go:""GO:0045177""(apical part of cell)|go:""GO:0045202""(synapse)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046914""(transition metal ion binding)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048143""(astrocyte activation)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|interpro:IPR013803(Amyloidogenic glycoprotein, amyloid-beta peptide)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048669""(collateral sprouting in absence of injury)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050803""(regulation of synapse structure or activity)|go:""GO:0050808""(synapse organization)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0050890""(cognition)|go:""GO:0051124""(synaptic assembly at neuromuscular junction)|go:""GO:0051233""(spindle midzone)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051425""(PTB domain binding)|go:""GO:0051563""(smooth endoplasmic reticulum calcium ion homeostasis)|go:""GO:0055037""(recycling endosome)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0098815""(modulation of excitatory postsynaptic potential)|go:""GO:0098989""(NMDA selective glutamate receptor signaling pathway)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0180011""(cytosolic mRNA polyadenylation)|go:""GO:1900272""(negative regulation of long-term synaptic potentiation)|go:""GO:1900273""(positive regulation of long-term synaptic potentiation)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905606""(regulation of presynapse assembly)|go:""GO:1905607""(negative regulation of presynapse assembly)|go:""GO:1905908""(positive regulation of amyloid fibril formation)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990535""(neuron projection maintenance)|go:""GO:2000406""(positive regulation of T cell migration)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-114608|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-432720|reactome:R-HSA-444473|reactome:R-HSA-445989|reactome:R-HSA-844456|reactome:R-HSA-879415|reactome:R-HSA-8862803|reactome:R-HSA-8957275|reactome:R-HSA-933542|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-977225|reactome:R-HSA-9837999|refseq:NP_000475.1|refseq:NP_001129488.1|refseq:NP_001129601.1|refseq:NP_001129602.1|refseq:NP_001129603.1|refseq:NP_001191230.1|refseq:NP_001191231.1|refseq:NP_001191232.1|refseq:NP_958816.1|refseq:NP_958817.1|mint:MINT-7993540(identity)"	"refseq:NP_231099.1|go:""GO:0005534""(galactose binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042531""(positive regulation of tyrosine phosphorylation of STAT protein)|go:""GO:0042597""(periplasmic space)|go:""GO:0046812""(host cell surface binding)|go:""GO:0090729""(toxin activity)|go:""GO:1902494""(catalytic complex)|interpro:IPR001835(Heat-labile enterotoxin, B chain)|interpro:IPR008992(Enterotoxin, bacterial)|rcsb pdb:1CHP|rcsb pdb:1CHQ|rcsb pdb:1CT1|rcsb pdb:1FGB|rcsb pdb:1G8Z|rcsb pdb:1JR0|rcsb pdb:1MD2|rcsb pdb:1RCV|rcsb pdb:1RD9|rcsb pdb:1RDP|rcsb pdb:1RF2|rcsb pdb:1S5B|rcsb pdb:1S5C|rcsb pdb:1S5D|rcsb pdb:1S5E|rcsb pdb:1S5F|rcsb pdb:1XTC|rcsb pdb:2CHB|rcsb pdb:3CHB|rcsb pdb:3EFX|rcsb pdb:5ELC|rcsb pdb:5ELE|rcsb pdb:5ELF|rcsb pdb:5LZG|rcsb pdb:5LZJ|rcsb pdb:6HJD|rcsb pdb:6HMW|rcsb pdb:6HMY|rcsb pdb:6HSV|rcsb pdb:7LVB|rcsb pdb:8OXS|rcsb pdb:8QRE|refseq:WP_000593522.1|mint:P01556|dip:DIP-6256N|mint:MINT-7993552(identity)"	"go:""GO:0045121""(membrane raft)"	-	-	figure legend:f3b|comment:mint|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells)	-	2010/09/01	2025/03/31	rogid:HatR8w8+mNjtjr7s5+bAwaStpmk9606	rogid:i5ZR7CiY2sBXsmmn1mNNPRMV9JU243277	intact-crc:8CDD402600A26FE9|rigid:FvUNMWJQIEj/facZ7zoHQxise2E	false	binding-associated region:672-713(MINT-7993541)|tag:?-?(MINT-7993543)	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P00747	uniprotkb:Q99SU7	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-7689378|intact:MINT-8304126	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:sak_staan(display_long)|uniprotkb:sak(gene name)|psi-mi:sak(display_short)|uniprotkb:SA1758(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Singh et al. (2012)	pubmed:22321644|imex:IM-16821|mint:MINT-8304097|mint:d-11-02066|doi:10.1016/j.febslet.2012.01.046	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:158879(staan)|taxid:158879(""Staphylococcus aureus (strain N315)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7689389|mint:MINT-8304536|imex:IM-16821-1	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)|mint:MINT-8304539(identity)"	"interpro:IPR004093(Staphylokinase/Streptokinase)|refseq:WP_000920042.1|interpro:IPR036120|mint:Q99SU7|go:""GO:0005576""(extracellular region)|mint:MINT-8304538(identity)"	-	-	comment:mint	comment:mint|figure legend:t2 sf1 sf2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:11.0x10^-6(molar)	2012/01/23	2025/03/31	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:+l+QJDA9qk5Ix/Cx60Pzmw41P5s158879	intact-crc:9C1553B312F43F7D|rigid:7sCjHISAjewgrLL/Fqj1abJYqs8	false	biotin tag:?-?(MINT-8304544)	mutation disrupting interaction:69-69(MINT-8304549)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00747	uniprotkb:Q99SU7	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-7689378|intact:MINT-8304126	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:sak_staan(display_long)|uniprotkb:sak(gene name)|psi-mi:sak(display_short)|uniprotkb:SA1758(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Singh et al. (2012)	pubmed:22321644|imex:IM-16821|mint:MINT-8304097|mint:d-11-02066|doi:10.1016/j.febslet.2012.01.046	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:158879(staan)|taxid:158879(""Staphylococcus aureus (strain N315)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7689409|mint:MINT-8304553|imex:IM-16821-2	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)|mint:MINT-8304560(identity)"	"interpro:IPR004093(Staphylokinase/Streptokinase)|refseq:WP_000920042.1|interpro:IPR036120|mint:Q99SU7|go:""GO:0005576""(extracellular region)|mint:MINT-8304556(identity)"	-	-	comment:mint	comment:mint|figure legend:t2 sf1 sf2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:11.0x10^-6(molar)	2012/01/23	2025/03/31	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:+l+QJDA9qk5Ix/Cx60Pzmw41P5s158879	intact-crc:4B46BACE84F22232|rigid:7sCjHISAjewgrLL/Fqj1abJYqs8	false	biotin tag:?-?(MINT-8304561)	mutation disrupting interaction:72-72(MINT-8304557)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00747	uniprotkb:Q99SU7	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-7689378|intact:MINT-8304126	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:sak_staan(display_long)|uniprotkb:sak(gene name)|psi-mi:sak(display_short)|uniprotkb:SA1758(locus name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Singh et al. (2012)	pubmed:22321644|imex:IM-16821|mint:MINT-8304097|mint:d-11-02066|doi:10.1016/j.febslet.2012.01.046	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:158879(staan)|taxid:158879(""Staphylococcus aureus (strain N315)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7689446|mint:MINT-8304567|imex:IM-16821-3	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)|mint:MINT-8304574(identity)"	"interpro:IPR004093(Staphylokinase/Streptokinase)|refseq:WP_000920042.1|interpro:IPR036120|mint:Q99SU7|go:""GO:0005576""(extracellular region)|mint:MINT-8304570(identity)"	-	-	comment:mint	comment:mint|figure legend:t2 sf2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:60.0x10^-6(molar)	2012/01/23	2025/03/31	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:+l+QJDA9qk5Ix/Cx60Pzmw41P5s158879	intact-crc:D6865C874DB09831|rigid:7sCjHISAjewgrLL/Fqj1abJYqs8	false	biotin tag:?-?(MINT-8304575)	mutation decreasing interaction:72-72(MINT-8304571)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00747	uniprotkb:Q99SU7	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-7689378|intact:MINT-8304126	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:sak_staan(display_long)|uniprotkb:sak(gene name)|psi-mi:sak(display_short)|uniprotkb:SA1758(locus name)	"psi-mi:""MI:0415""(enzymatic study)"	Singh et al. (2012)	pubmed:22321644|imex:IM-16821|mint:MINT-8304097|mint:d-11-02066|doi:10.1016/j.febslet.2012.01.046	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:158879(staan)|taxid:158879(""Staphylococcus aureus (strain N315)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7689476|mint:MINT-8304582|imex:IM-16821-4	intact-miscore:0.56	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0840""(stimulator)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)|mint:MINT-8304589(identity)"	"interpro:IPR004093(Staphylokinase/Streptokinase)|refseq:WP_000920042.1|interpro:IPR036120|mint:Q99SU7|go:""GO:0005576""(extracellular region)|mint:MINT-8304585(identity)"	-	-	comment:mint	comment:mint|figure legend:t1 f2a f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	km:0.7x10^-6(molar)	2012/01/23	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:+l+QJDA9qk5Ix/Cx60Pzmw41P5s158879	intact-crc:94FE0E716F0191CB|rigid:7sCjHISAjewgrLL/Fqj1abJYqs8	false	-	-	-	-	"psi-mi:""MI:0823""(predetermined feature)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99SU7	uniprotkb:P00747	intact:EBI-7689378|intact:MINT-8304126	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:sak_staan(display_long)|uniprotkb:sak(gene name)|psi-mi:sak(display_short)|uniprotkb:SA1758(locus name)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0415""(enzymatic study)"	Singh et al. (2012)	pubmed:22321644|imex:IM-16821|mint:MINT-8304097|mint:d-11-02066|doi:10.1016/j.febslet.2012.01.046	"taxid:158879(staan)|taxid:158879(""Staphylococcus aureus (strain N315)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7689488|mint:MINT-8304600|imex:IM-16821-5	intact-miscore:0.56	-	"psi-mi:""MI:0840""(stimulator)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004093(Staphylokinase/Streptokinase)|refseq:WP_000920042.1|interpro:IPR036120|mint:Q99SU7|go:""GO:0005576""(extracellular region)|mint:MINT-8304605(identity)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)|mint:MINT-8304603(identity)"	-	comment:mint	-	comment:mint|figure legend:t1 f2a f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	km:2.0x10^-6(molar)	2012/01/23	2024/11/14	rogid:+l+QJDA9qk5Ix/Cx60Pzmw41P5s158879	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:E70EB5AE9AAF74AD|rigid:7sCjHISAjewgrLL/Fqj1abJYqs8	false	mutation decreasing interaction:69-69(MINT-8304610)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0823""(predetermined feature)"
uniprotkb:Q99SU7	uniprotkb:P00747	intact:EBI-7689378|intact:MINT-8304126	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:sak_staan(display_long)|uniprotkb:sak(gene name)|psi-mi:sak(display_short)|uniprotkb:SA1758(locus name)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0415""(enzymatic study)"	Singh et al. (2012)	pubmed:22321644|imex:IM-16821|mint:MINT-8304097|mint:d-11-02066|doi:10.1016/j.febslet.2012.01.046	"taxid:158879(staan)|taxid:158879(""Staphylococcus aureus (strain N315)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7689505|mint:MINT-8304613|imex:IM-16821-6	intact-miscore:0.56	-	"psi-mi:""MI:0840""(stimulator)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004093(Staphylokinase/Streptokinase)|refseq:WP_000920042.1|interpro:IPR036120|mint:Q99SU7|go:""GO:0005576""(extracellular region)|mint:MINT-8304618(identity)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)|mint:MINT-8304616(identity)"	-	comment:mint	-	comment:mint|figure legend:t1 f2a f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	km:1.9x10^-6(molar)	2012/01/23	2024/11/14	rogid:+l+QJDA9qk5Ix/Cx60Pzmw41P5s158879	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:E977C3FE5C0FBD30|rigid:7sCjHISAjewgrLL/Fqj1abJYqs8	false	mutation decreasing interaction:72-72(MINT-8304619)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0823""(predetermined feature)"
uniprotkb:Q99SU7	uniprotkb:P00747	intact:EBI-7689378|intact:MINT-8304126	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:sak_staan(display_long)|uniprotkb:sak(gene name)|psi-mi:sak(display_short)|uniprotkb:SA1758(locus name)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0415""(enzymatic study)"	Singh et al. (2012)	pubmed:22321644|imex:IM-16821|mint:MINT-8304097|mint:d-11-02066|doi:10.1016/j.febslet.2012.01.046	"taxid:158879(staan)|taxid:158879(""Staphylococcus aureus (strain N315)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7689554|mint:MINT-8304642|imex:IM-16821-8	intact-miscore:0.56	-	"psi-mi:""MI:0840""(stimulator)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004093(Staphylokinase/Streptokinase)|refseq:WP_000920042.1|interpro:IPR036120|mint:Q99SU7|go:""GO:0005576""(extracellular region)|mint:MINT-8304647(identity)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)|mint:MINT-8304645(identity)"	-	comment:mint	-	comment:mint|figure legend:t1 f2a f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	km:4.2x10^-6(molar)	2012/01/23	2024/11/14	rogid:+l+QJDA9qk5Ix/Cx60Pzmw41P5s158879	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:6EBF36D4BB0A3064|rigid:7sCjHISAjewgrLL/Fqj1abJYqs8	false	mutation decreasing interaction:71-71(MINT-8304653)|mutation decreasing interaction:72-72(MINT-8304648)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A7GBG3	uniprotkb:P63027	intact:EBI-7604673|intact:MINT-8297602|uniprotkb:Q79AH9	intact:EBI-520113|uniprotkb:P19065|uniprotkb:Q9BUC2|ensembl:ENSP00000314214.6	psi-mi:bxf_clobl(display_long)|uniprotkb:F(gene name)|psi-mi:F(display_short)|uniprotkb:Bontoxilysin-F(gene name synonym)|uniprotkb:boNT/F(gene name synonym)|uniprotkb:bont(gene name synonym)|uniprotkb:CLI_0851(locus name)	psi-mi:vamp2_human(display_long)|uniprotkb:Synaptobrevin-2(gene name synonym)|uniprotkb:VAMP2(gene name)|psi-mi:VAMP2(display_short)|uniprotkb:SYB2(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Kalb et al. (2012)	pubmed:22172278|imex:IM-16752|mint:MINT-8297613|doi:10.1016/j.febslet.2011.11.033	"taxid:441772(clobl)|taxid:441772(""Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7604668|mint:MINT-8297663|imex:IM-16752-1	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A7GBG3|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR012500(Clostridium neurotoxin, translocation)|refseq:WP_011987710.1|interpro:IPR036248|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008289""(lipid binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044231""(host cell presynaptic membrane)|go:""GO:0090729""(toxin activity)|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3FUQ|rcsb pdb:3RSJ|mint:MINT-8297665(identity)"	"refseq:NP_055047.2|ensembl:ENSG00000220205.10(gene)|ensembl:ENST00000316509.11(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0009749""(response to glucose)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016079""(synaptic vesicle exocytosis)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043308""(eosinophil degranulation)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0045202""(synapse)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0060203""(clathrin-sculpted glutamate transport vesicle membrane)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0061025""(membrane fusion)|go:""GO:0061202""(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070032""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:""GO:0070033""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:""GO:0070044""(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:""GO:0070083""(clathrin-sculpted monoamine transport vesicle membrane)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:1902259""(regulation of delayed rectifier potassium channel activity)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:P63027|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:7UDC|reactome:R-HSA-1445148|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-199992|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-449836|reactome:R-HSA-5250955|reactome:R-HSA-5250958|reactome:R-HSA-5250981|reactome:R-HSA-5250982|reactome:R-HSA-5250989|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|dip:DIP-39072N|panther:PTHR45701(orthology-group)|mint:MINT-8297666(identity)"	-	comment:mint	-	figure legend:f1a f1b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2025/03/31	rogid:PUSLjCpFP271xW5Us+YdTAAnC/8441772	rogid:uuuJXsI5sr7fzjxuBhSYDHJZp9M9606	intact-crc:473268825DCBA7AC|rigid:t1/kceteUm9Je77UKWw96yRik4Y	false	glutathione s tranferase tag:?-?(MINT-8297668)	uncategorized protein modification:58-59(MINT-8297675)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:D2KHQ9	uniprotkb:P63027	intact:EBI-7604762|intact:MINT-8297604	intact:EBI-520113|uniprotkb:P19065|uniprotkb:Q9BUC2|ensembl:ENSP00000314214.6	psi-mi:d2khq9_clobo(display_long)	psi-mi:vamp2_human(display_long)|uniprotkb:Synaptobrevin-2(gene name synonym)|uniprotkb:VAMP2(gene name)|psi-mi:VAMP2(display_short)|uniprotkb:SYB2(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Kalb et al. (2012)	pubmed:22172278|imex:IM-16752|mint:MINT-8297613|doi:10.1016/j.febslet.2011.11.033	taxid:1491(clobo)|taxid:1491(Clostridium botulinum)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7604757|mint:MINT-8297679|imex:IM-16752-2	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:D2KHQ9|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR012500(Clostridium neurotoxin, translocation)|refseq:WP_021107080.1|interpro:IPR036248|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0090729""(toxin activity)|mint:MINT-8297681(identity)"	"refseq:NP_055047.2|ensembl:ENSG00000220205.10(gene)|ensembl:ENST00000316509.11(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0009749""(response to glucose)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016079""(synaptic vesicle exocytosis)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043308""(eosinophil degranulation)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0045202""(synapse)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0060203""(clathrin-sculpted glutamate transport vesicle membrane)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0061025""(membrane fusion)|go:""GO:0061202""(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070032""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:""GO:0070033""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:""GO:0070044""(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:""GO:0070083""(clathrin-sculpted monoamine transport vesicle membrane)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:1902259""(regulation of delayed rectifier potassium channel activity)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:P63027|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:7UDC|reactome:R-HSA-1445148|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-199992|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-449836|reactome:R-HSA-5250955|reactome:R-HSA-5250958|reactome:R-HSA-5250981|reactome:R-HSA-5250982|reactome:R-HSA-5250989|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|dip:DIP-39072N|panther:PTHR45701(orthology-group)|mint:MINT-8297685(identity)"	-	comment:mint	-	figure legend:f2a f2b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2025/03/05	rogid:quu0HvEq0TNppW93skiJ98mmLmw1491	rogid:uuuJXsI5sr7fzjxuBhSYDHJZp9M9606	intact-crc:FB0D61BBECF2D2BD|rigid:5SE7JUCetv+tn0JD/NahXy85d3A	false	glutathione s tranferase tag:?-?(MINT-8297682)	uncategorized protein modification:58-59(MINT-8297686)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:D2KHQ9	uniprotkb:P63027	intact:EBI-7604762|intact:MINT-8297604	intact:EBI-520113|uniprotkb:P19065|uniprotkb:Q9BUC2|ensembl:ENSP00000314214.6	psi-mi:d2khq9_clobo(display_long)	psi-mi:vamp2_human(display_long)|uniprotkb:Synaptobrevin-2(gene name synonym)|uniprotkb:VAMP2(gene name)|psi-mi:VAMP2(display_short)|uniprotkb:SYB2(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Kalb et al. (2012)	pubmed:22172278|imex:IM-16752|mint:MINT-8297613|doi:10.1016/j.febslet.2011.11.033	taxid:1491(clobo)|taxid:1491(Clostridium botulinum)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7604813|mint:MINT-8297699|imex:IM-16752-3	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:D2KHQ9|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR012500(Clostridium neurotoxin, translocation)|refseq:WP_021107080.1|interpro:IPR036248|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0090729""(toxin activity)|mint:MINT-8297705(identity)"	"refseq:NP_055047.2|ensembl:ENSG00000220205.10(gene)|ensembl:ENST00000316509.11(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0009749""(response to glucose)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016079""(synaptic vesicle exocytosis)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043308""(eosinophil degranulation)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0045202""(synapse)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0060203""(clathrin-sculpted glutamate transport vesicle membrane)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0061025""(membrane fusion)|go:""GO:0061202""(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070032""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:""GO:0070033""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:""GO:0070044""(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:""GO:0070083""(clathrin-sculpted monoamine transport vesicle membrane)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:1902259""(regulation of delayed rectifier potassium channel activity)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:P63027|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:7UDC|reactome:R-HSA-1445148|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-199992|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-449836|reactome:R-HSA-5250955|reactome:R-HSA-5250958|reactome:R-HSA-5250981|reactome:R-HSA-5250982|reactome:R-HSA-5250989|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|dip:DIP-39072N|panther:PTHR45701(orthology-group)|mint:MINT-8297701(identity)"	-	comment:mint	-	comment:mint|figure legend:f2c f2d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2025/03/05	rogid:quu0HvEq0TNppW93skiJ98mmLmw1491	rogid:uuuJXsI5sr7fzjxuBhSYDHJZp9M9606	intact-crc:79013CFDB0B0F4D6|rigid:5SE7JUCetv+tn0JD/NahXy85d3A	false	glutathione s tranferase tag:?-?(MINT-8297706)	binding-associated region:32-70(MINT-8297712)|uncategorized protein modification:58-59(MINT-8297702)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0083""(peptide synthesis)"
uniprotkb:A7GBG3	uniprotkb:P63027	intact:EBI-7604673|intact:MINT-8297602|uniprotkb:Q79AH9	intact:EBI-520113|uniprotkb:P19065|uniprotkb:Q9BUC2|ensembl:ENSP00000314214.6	psi-mi:bxf_clobl(display_long)|uniprotkb:F(gene name)|psi-mi:F(display_short)|uniprotkb:Bontoxilysin-F(gene name synonym)|uniprotkb:boNT/F(gene name synonym)|uniprotkb:bont(gene name synonym)|uniprotkb:CLI_0851(locus name)	psi-mi:vamp2_human(display_long)|uniprotkb:Synaptobrevin-2(gene name synonym)|uniprotkb:VAMP2(gene name)|psi-mi:VAMP2(display_short)|uniprotkb:SYB2(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Kalb et al. (2012)	pubmed:22172278|imex:IM-16752|mint:MINT-8297613|doi:10.1016/j.febslet.2011.11.033	"taxid:441772(clobl)|taxid:441772(""Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7604871|mint:MINT-8297715|imex:IM-16752-4	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:A7GBG3|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR012500(Clostridium neurotoxin, translocation)|refseq:WP_011987710.1|interpro:IPR036248|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008289""(lipid binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044231""(host cell presynaptic membrane)|go:""GO:0090729""(toxin activity)|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3FUQ|rcsb pdb:3RSJ|mint:MINT-8297723(identity)"	"refseq:NP_055047.2|ensembl:ENSG00000220205.10(gene)|ensembl:ENST00000316509.11(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0009749""(response to glucose)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016079""(synaptic vesicle exocytosis)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043308""(eosinophil degranulation)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0045202""(synapse)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0060203""(clathrin-sculpted glutamate transport vesicle membrane)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0061025""(membrane fusion)|go:""GO:0061202""(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070032""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:""GO:0070033""(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:""GO:0070044""(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:""GO:0070083""(clathrin-sculpted monoamine transport vesicle membrane)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:1902259""(regulation of delayed rectifier potassium channel activity)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:P63027|rcsb pdb:3FIE|rcsb pdb:3FII|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:7UDC|reactome:R-HSA-1445148|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-199992|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-264876|reactome:R-HSA-422356|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-449836|reactome:R-HSA-5250955|reactome:R-HSA-5250958|reactome:R-HSA-5250981|reactome:R-HSA-5250982|reactome:R-HSA-5250989|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-9609523|reactome:R-HSA-9662360|dip:DIP-39072N|panther:PTHR45701(orthology-group)|mint:MINT-8297717(identity)"	-	comment:mint	-	figure legend:f1c f1d|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/02	2025/03/31	rogid:PUSLjCpFP271xW5Us+YdTAAnC/8441772	rogid:uuuJXsI5sr7fzjxuBhSYDHJZp9M9606	intact-crc:AC3F9BA81E0DFC2E|rigid:t1/kceteUm9Je77UKWw96yRik4Y	false	glutathione s tranferase tag:?-?(MINT-8297724)	binding-associated region:32-70(MINT-8297718)|uncategorized protein modification:58-59(MINT-8297720)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0083""(peptide synthesis)"
uniprotkb:P01009	uniprotkb:P24664	intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068.4|ensembl:ENSP00000376802.4|ensembl:ENSP00000376803.4|ensembl:ENSP00000385960.4|ensembl:ENSP00000390299.1|ensembl:ENSP00000408474.1|ensembl:ENSP00000416066.1|ensembl:ENSP00000416354.3|ensembl:ENSP00000490054.1	intact:EBI-7572597|intact:MINT-8289191	psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym)	psi-mi:tryp_sacer(display_long)|uniprotkb:SET(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Vukoti et al. (2011)	pubmed:22115549|imex:IM-16735|mint:MINT-8288865|mint:d-11-01536|doi:10.1016/j.febslet.2011.11.015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1836(sacer)|taxid:1836(Saccharopolyspora erythraea)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7572609|mint:MINT-8288913|imex:IM-16735-2	intact-miscore:0.44	-	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:178396""|efo:""Orphanet:586""|efo:""Orphanet:60""|dip:DIP-35493N|ensembl:ENSG00000197249.14(gene)|ensembl:ENST00000355814.8(transcript)|ensembl:ENST00000393087.9(transcript)|ensembl:ENST00000393088.8(transcript)|ensembl:ENST00000404814.8(transcript)|ensembl:ENST00000437397.5(transcript)|ensembl:ENST00000440909.5(transcript)|ensembl:ENST00000448921.5(transcript)|ensembl:ENST00000449399.7(transcript)|ensembl:ENST00000636712.1(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006953""(acute-phase response)|go:""GO:0007596""(blood coagulation)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1D5S|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:8P4J|rcsb pdb:8P4U|rcsb pdb:8PI2|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275|refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|panther:PTHR11461(orthology-group)|mint:MINT-8288917(identity)"	"interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR018114|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR033116|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|interpro:IPR050430|rcsb pdb:4M7G|rcsb pdb:5DK1|interpro:IPR043504|mint:P24664|mint:MINT-8288915(identity)"	-	-	comment:mint	figure legend:f3|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/08	2025/03/10	rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606	rogid:Nu+9iEmKolwMZ/1Wt9hJhpOjjIc1836	intact-crc:2EA863A931797E03|rigid:KBYEiobUbbg3TWQQK4S9nmvWOmU	false	uncategorized protein modification:358-359(MINT-8288918)	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:P02671	intact:EBI-6252260	intact:EBI-348571|uniprotkb:Q9BX62|uniprotkb:Q9UCH2|uniprotkb:A8K3E4|ensembl:ENSP00000498441.1|uniprotkb:Q4QQH7|uniprotkb:D3DP14|uniprotkb:D3DP15	-	psi-mi:fiba_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short)	psi-mi:crlkekhc(display_short)|psi-mi:EBI-6252260(display_long)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Houimel et al. (2012)	pubmed:22100634|imex:IM-17881	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0917""(matrixdb)"	intact:EBI-6252258|imex:IM-17881-1	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0327""(peptide)"	"reactome:R-HSA-216083|ensembl:ENSG00000171560.18(gene)|ensembl:ENST00000651975.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043152""(induction of bacterial agglutination)|go:""GO:0045087""(innate immune response)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0046872""(metal ion binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051258""(protein polymerization)|go:""GO:0051592""(response to calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0072377""(blood coagulation, common pathway)|go:""GO:0072378""(blood coagulation, fibrin clot formation)|go:""GO:0072562""(blood microparticle)|go:""GO:0090277""(positive regulation of peptide hormone secretion)|reactome:R-HSA-354192|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903561""(extracellular vesicle)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR021996|interpro:IPR036056|interpro:IPR037579|mint:P02671|rcsb pdb:1BBR|rcsb pdb:1DM4|rcsb pdb:1FPH|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZD|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:1YCP|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3AT0|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4F27|rcsb pdb:5CFA|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-977225|refseq:NP_000499.1|refseq:NP_068657.1|dip:DIP-29643N|efo:""Orphanet:101041""|efo:""Orphanet:248408""|efo:""Orphanet:93562""|efo:""Orphanet:98880""|efo:""Orphanet:98881""|panther:PTHR47221(orthology-group)"	-	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/24	2025/01/22	rogid:khlQGVpd+6qZLTrsT9KxlxgjMR09606	rogid:6+o96XmgGPLDbLoblJ5G6wK0P5g83333	intact-crc:29624937778555BD|rigid:h3N+/Dq5UBVacJSZTFwXc+0pCIE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-6252260	reactome:R-HSA-114618	-	intact:EBI-6397384|reactome:R-HSA-114617|matrixdb:MULT_23_human|wwpdb:3ghg|wwpdb:3bvh|signor:SIGNOR-C311	psi-mi:crlkekhc(display_short)|psi-mi:EBI-6252260(display_long)	"psi-mi:fibrinogen_human(display_short)|psi-mi:R-HSA-114618(display_long)|intact:Fibrinogen complex(complex recommended name)|intact:FIBA-FIBB-FIBG complex(complex synonym)|intact:""2xFGA:2xFGB:2xFGG""(complex systematic name)"	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Houimel et al. (2012)	pubmed:22100634|imex:IM-17881	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0917""(matrixdb)"	intact:EBI-6252277|imex:IM-17881-4	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0327""(peptide)"	"psi-mi:""MI:1302""(stable complex)"	-	"intact:EBI-1034460(exp-evidence)|pubmed:12356313(see-also)|humap:huMAP3_06675.1(subset)|evidence ontology:""ECO:0000353""|complex portal:CPX-1922(complex-primary)|efo:""MONDO:0007099""(see-also)|efo:""MONDO:0008737""(see-also)|efo:""MONDO:0014452""(see-also)|pubmed:12524220(see-also)|pubmed:16846481(see-also)|pubmed:19296670(see-also)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005615""(extracellular space)|go:""GO:0072378""(blood coagulation, fibrin clot formation)|pubmed:18294856(see-also)"	-	-	"complex-properties:""\""Two alpha-beta-gamma fibrinogen heterotrimers are linked to each other by 29 disulfide bonds in a molecule with bilateral symmetry. The 2 heterotrimers are in a head to head conformation with the N-termini in a small central domain. Alpha-thrombin removes small peptides from the amino termini of the alpha and beta chains, exposing sets of \\""knobs\\"" that interact noncovalently with ever-present \\""holes\\"" on neighbouring molecules to form oligomers termed protofibrils. As polymerization progresses, factor XIIIa (CPX-6231) incorporates covalent cross-links, initially between the carboxy-terminal segments of gamma chains, but eventually also including alpha chains.     MW: 340-kDa\""""|disease:""\""Familial afibrinogenemia [MONDO:0008737]: a coagulation disorder characterized by bleeding symptoms due to a complete absence of circulating fibrinogen.\""""|disease:""\""Familial renal amyloidosis [MONDO:0007099]: a type of hereditary amyloidosis. Hereditary amyloidosis is characterized by the deposit of an abnormal protein called amyloid in multiple organs of the body where it should not be, which causes disruption of organ tissue structure and function. Clinical features include extensive visceral amyloid deposits, renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash. There is no involvement of the nervous system. Fibrinogen Aα-chain amyloidosis (A Fib) is a subtype of hereditary amyloidosis.\""""|disease:""\""Familial dysfibrinogenemia [MONDO:0014452]: a coagulation disorder characterized by a bleeding tendency due to a functional anomaly of circulating fibrinogen.\""""|curated-complex:""\""Glycoprotein complex that forms fibrin clots as the last step of the coagulation pathway. Fibrinogen heterohexamers (this complex) are activated by minor proteolysis of alpha and beta chains by alpha-thrombin complex (CPX-6222) to form so-called fibrin monomers (CPX-6225). Fibrin clot (CPX-6230) formation is catalysed by factor XIIIa (CPX-6231). Clots are dissolved mainly by the proteolytic action of plasmin (P00747).\""""|complex-assembly:Heterohexamer"	figure legend:3A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/24	2024/11/14	rogid:6+o96XmgGPLDbLoblJ5G6wK0P5g83333	-	intact-crc:486B1D01F2DFDFDA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P01024	intact:EBI-6252260	intact:EBI-905851|uniprotkb:A7E236|ensembl:ENSP00000245907.4	-	psi-mi:co3_human(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)|uniprotkb:CPAMD1(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1(gene name synonym)	psi-mi:crlkekhc(display_short)|psi-mi:EBI-6252260(display_long)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Houimel et al. (2012)	pubmed:22100634|imex:IM-17881	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0917""(matrixdb)"	intact:EBI-6252281|imex:IM-17881-2	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0327""(peptide)"	"efo:""Orphanet:280133""|efo:""Orphanet:544472""|ensembl:ENSG00000125730.18(gene)|ensembl:ENST00000245907.11(transcript)|go:""GO:0001798""(positive regulation of type IIa hypersensitivity)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001970""(positive regulation of activation of membrane attack complex)|go:""GO:0002430""(complement receptor mediated signaling pathway)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007165""(signal transduction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0009617""(response to bacterium)|go:""GO:0009986""(cell surface)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010828""(positive regulation of D-glucose transmembrane transport)|go:""GO:0010866""(regulation of triglyceride biosynthetic process)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0016322""(neuron remodeling)|go:""GO:0031715""(C5L2 anaphylatoxin chemotactic receptor binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035846""(oviduct epithelium development)|go:""GO:0042113""(B cell activation)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0097278""(complement-dependent cytotoxicity)|go:""GO:0150062""(complement-mediated synapse pruning)|go:""GO:0150064""(vertebrate eye-specific patterning)|go:""GO:2000427""(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|interpro:IPR047565|interpro:IPR048848|interpro:IPR049466|interpro:IPR050473|mint:P01024|rcsb pdb:1C3D|rcsb pdb:1GHQ|rcsb pdb:1W2S|rcsb pdb:2A73|rcsb pdb:2A74|rcsb pdb:2GOX|rcsb pdb:2I07|rcsb pdb:2ICE|rcsb pdb:2ICF|rcsb pdb:2NOJ|rcsb pdb:2QKI|rcsb pdb:2WII|rcsb pdb:2WIN|rcsb pdb:2WY7|rcsb pdb:2WY8|rcsb pdb:2XQW|rcsb pdb:2XWB|rcsb pdb:2XWJ|rcsb pdb:3D5R|rcsb pdb:3D5S|rcsb pdb:3G6J|rcsb pdb:3L3O|rcsb pdb:3L5N|rcsb pdb:3NMS|rcsb pdb:3OED|rcsb pdb:3OHX|rcsb pdb:3OXU|rcsb pdb:3RJ3|rcsb pdb:3T4A|rcsb pdb:4HW5|rcsb pdb:4HWJ|rcsb pdb:4I6O|rcsb pdb:4M76|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5FO7|rcsb pdb:5FO8|rcsb pdb:5FO9|rcsb pdb:5FOA|rcsb pdb:5FOB|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:6EHG|rcsb pdb:6RMT|rcsb pdb:6RMU|rcsb pdb:6RUR|rcsb pdb:6RUV|rcsb pdb:6S0B|rcsb pdb:6YO6|rcsb pdb:7AKK|rcsb pdb:7BAG|rcsb pdb:7NOZ|rcsb pdb:7PI6|rcsb pdb:7QIV|rcsb pdb:7TV9|rcsb pdb:7UE9|rcsb pdb:7ZGK|rcsb pdb:8ENU|rcsb pdb:8EOK|rcsb pdb:8HK2|rcsb pdb:8I9L|rcsb pdb:8OQ3|rcsb pdb:8OVB|rcsb pdb:8UH2|rcsb pdb:8UIN|reactome:R-HSA-173736|reactome:R-HSA-174577|reactome:R-HSA-198933|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-418594|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9660826|reactome:R-HSA-977606|refseq:NP_000055.2|dip:DIP-35180N|panther:PTHR11412(orthology-group)"	-	-	-	-	figure legend:3A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/24	2025/01/26	rogid:6Axa89cCPpUXFsLnd7sCurZzLYI9606	rogid:6+o96XmgGPLDbLoblJ5G6wK0P5g83333	intact-crc:F08B8A8DC42DBA80|rigid:Ms3o+94UOP3AsPNcD2ZMis4dFSQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
matrixdb:MULT_82_human	intact:EBI-6252260	intact:EBI-6264901|reactome:R-HSA-173579|wwpdb:1PK6|wwpdb:2wnv|wwpdb:2jg8|wwpdb:2jg9|wwpdb:2wnu|reactome:R-HSA-173588|signor:SIGNOR-C308	-	"psi-mi:c1q_human(display_short)|psi-mi:MULT_82_human(display_long)|intact:Complement component C1q complex(complex recommended name)|intact:C1q(complex synonym)|intact:Complement 1q(complex synonym)|intact:C1QA-C1QB-C1QC complex(complex synonym)|intact:""6xC1QA:6xC1QB:6xC1QC""(complex systematic name)"	psi-mi:crlkekhc(display_short)|psi-mi:EBI-6252260(display_long)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Houimel et al. (2012)	pubmed:22100634|imex:IM-17881	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0917""(matrixdb)"	intact:EBI-6252287|imex:IM-17881-5	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:1302""(stable complex)"	"psi-mi:""MI:0327""(peptide)"	"go:""GO:0005509""(calcium ion binding)|pubmed:28601358(see-also)|pubmed:22536204(see-also)|intact:EBI-6264878(exp-evidence)|go:""GO:0019865""(immunoglobulin binding)|efo:""MONDO:0013343""(see-also)|evidence ontology:""ECO:0000353""|complex portal:CPX-1919(complex-primary)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0005576""(extracellular region)|pubmed:20548024(see-also)|pubmed:29449492(see-also)|pubmed:18250442(see-also)|go:""GO:0062167""(complement component C1q complex)|pubmed:31165008(see-also)|pubmed:27914690(see-also)|pubmed:26489954(see-also)"	-	-	"disease:""\""Complement component C1q deficiency (C1QD) [MONDO:0013343]: a disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.\""""|complex-properties:The complex comprises of six heterotrimeric collagen-like triple helices, formed from triplets of the A, B, and C chains, that associate in their N-terminal half to form a stalk, then diverge to form individual stems, each terminating in a C-terminal globular domain. Each of the six heterotrimeric globular heads or domains is made up of the globular domains from one A, one B, and one C chain, each of which in turn has its own ligand specificity. The six collagen-like stalks appear to be fibril-like and exist in the central region. The collagen-like region and the globular heads can independently interact with a multiplicity of biological structures including pathogen-associated and cell associated molecules, also each of the individual globular head domains is capable of independently interacting with specific ligands. Chains A and B are disulfide-linked whilst the C chain forms a disulfide bond with the C chain of the next strand.     Molecular weight 460 kDa.|curated-complex:""\""Recognition unit of the classical pathway of complement which associates with the Ca2+ - dependent C1r(2)-C1s(2) tetramer to form C1 (CPX-1920), the first component of the classical complement system. The complex's role in C1 is the recognition of immune complexes, or other molecules, which trigger the classical pathway of the complement system. Independent of complement activation C1q appears to have additional roles in homeostasis and cellular development, superoxide (O2-) production by neutrophils, blood coagulation and neurological synapse pruning.\""""|complex-assembly:Heterooctadecamer"	-	figure legend:3A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/24	2024/11/14	-	rogid:6+o96XmgGPLDbLoblJ5G6wK0P5g83333	intact-crc:4F58E4EF9FF2796C	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P11215	intact:EBI-6252260	intact:EBI-2568251|uniprotkb:Q4VAK0|uniprotkb:Q4VAK2|ensembl:ENSP00000441691.3|uniprotkb:Q4VAK1	-	psi-mi:itam_human(display_long)|uniprotkb:ITGAM(gene name)|psi-mi:ITGAM(display_short)|uniprotkb:CD11B(gene name synonym)|uniprotkb:CR3A(gene name synonym)|uniprotkb:Cell surface glycoprotein MAC-1 subunit alpha(gene name synonym)|uniprotkb:CR-3 alpha chain(gene name synonym)|uniprotkb:Leukocyte adhesion receptor MO1(gene name synonym)|uniprotkb:Neutrophil adherence receptor(gene name synonym)|uniprotkb:CD11 antigen-like family member B(gene name synonym)	psi-mi:crlkekhc(display_short)|psi-mi:EBI-6252260(display_long)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Houimel et al. (2012)	pubmed:22100634|imex:IM-17881	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0917""(matrixdb)"	intact:EBI-6252477|imex:IM-17881-3	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0327""(peptide)"	"ensembl:ENSG00000169896.18(gene)|ensembl:ENST00000544665.9(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0002430""(complement receptor mediated signaling pathway)|go:""GO:0002931""(response to ischemia)|go:""GO:0005178""(integrin binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010668""(ectodermal cell differentiation)|go:""GO:0030900""(forebrain development)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034688""(integrin alphaM-beta2 complex)|go:""GO:0035579""(specific granule membrane)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0043315""(positive regulation of neutrophil degranulation)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045087""(innate immune response)|go:""GO:0045963""(negative regulation of dopamine metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:0140459""(response to Gram-positive bacterium)|go:""GO:0150062""(complement-mediated synapse pruning)|go:""GO:0150064""(vertebrate eye-specific patterning)|go:""GO:1904151""(positive regulation of microglial cell mediated cytotoxicity)|go:""GO:1904643""(response to curcumin)|go:""GO:2000363""(positive regulation of prostaglandin-E synthase activity)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|interpro:IPR048285|interpro:IPR048633|mint:P11215|rcsb pdb:1BHO|rcsb pdb:1BHQ|rcsb pdb:1IDN|rcsb pdb:1IDO|rcsb pdb:1JLM|rcsb pdb:1M1U|rcsb pdb:1MF7|rcsb pdb:1N9Z|rcsb pdb:1NA5|rcsb pdb:2LKE|rcsb pdb:2LKJ|rcsb pdb:3Q3G|rcsb pdb:3QA3|rcsb pdb:4M76|rcsb pdb:4XW2|rcsb pdb:6RHW|rcsb pdb:7AKK|rcsb pdb:7P2D|rcsb pdb:7USL|rcsb pdb:7USM|rcsb pdb:8CE6|rcsb pdb:8CE9|rcsb pdb:8VOH|rcsb pdb:8VOI|reactome:R-HSA-166016|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000623.2|refseq:NP_001139280.1|efo:""Orphanet:536""|panther:PTHR23220(orthology-group)"	-	-	-	-	figure legend:6B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	ic50:3.35x10^-6 ~0.1(molar)	2012/07/24	2024/11/14	rogid:LdazC8w25LRfb+vgr/kGcKmIkYo9606	rogid:6+o96XmgGPLDbLoblJ5G6wK0P5g83333	intact-crc:B115CD365E9C53DC	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53971	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-20719966	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53971_strdy(display_long)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Schwarz-Linek et al. (2001)	pubmed:11377428|imex:IM-27571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1334(Streptococcus dysgalactiae)|taxid:1334(Streptococcus dysgalactiae)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20730028|imex:IM-27571-1	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|interpro:IPR041033|interpro:IPR019931|rcsb pdb:1O9A|interpro:IPR008454(Collagen-binding surface protein Cna-like, B region)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR013783(Immunoglobulin-like fold)"	-	-	-	figure legend:Fig 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/09/06	2025/03/25	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:3RdoEmgD0ZqhIsILQPNdDiNo1rg1334	intact-crc:B42FDA5A81410796|rigid:7eteQ6LrU5rgbOOpTDkyANhBGJo	false	binding-associated region:49-140	binding-associated region:1031-1066	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q53971	uniprotkb:P02751	intact:EBI-20719966	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q53971_strdy(display_long)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0077""(nuclear magnetic resonance)"	Schwarz-Linek et al. (2001)	pubmed:11377428|imex:IM-27571	taxid:1334(Streptococcus dysgalactiae)|taxid:1334(Streptococcus dysgalactiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20730036|imex:IM-27571-3	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|interpro:IPR041033|interpro:IPR019931|rcsb pdb:1O9A|interpro:IPR008454(Collagen-binding surface protein Cna-like, B region)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR013783(Immunoglobulin-like fold)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:Fig 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/09/06	2025/03/25	rogid:3RdoEmgD0ZqhIsILQPNdDiNo1rg1334	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:EFF2F52E4890F918|rigid:7eteQ6LrU5rgbOOpTDkyANhBGJo	false	binding-associated region:1031-1066	binding-associated region:49-140|15n label:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53971	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-20719966	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53971_strdy(display_long)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)	"psi-mi:""MI:1103""(solution state nmr)"	Schwarz-Linek et al. (2003)	imex:IM-26856|pubmed:12736686	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1334(Streptococcus dysgalactiae)|taxid:1334(Streptococcus dysgalactiae)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20719963|imex:IM-26856-1|wwpdb:1O9A	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|interpro:IPR041033|interpro:IPR019931|rcsb pdb:1O9A|interpro:IPR008454(Collagen-binding surface protein Cna-like, B region)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR013783(Immunoglobulin-like fold)"	-	-	-	figure legend:Fig 1, Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/16	2025/03/25	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:3RdoEmgD0ZqhIsILQPNdDiNo1rg1334	intact-crc:6C5F718BE2E2A694|rigid:7eteQ6LrU5rgbOOpTDkyANhBGJo	false	binding-associated region:48-140	binding-associated region:1031-1066	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q53971	uniprotkb:P02751	intact:EBI-20719966	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q53971_strdy(display_long)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Schwarz-Linek et al. (2003)	imex:IM-26856|pubmed:12736686	taxid:1334(Streptococcus dysgalactiae)|taxid:1334(Streptococcus dysgalactiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20729936|imex:IM-26856-3	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|interpro:IPR041033|interpro:IPR019931|rcsb pdb:1O9A|interpro:IPR008454(Collagen-binding surface protein Cna-like, B region)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR013783(Immunoglobulin-like fold)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:Fig 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/16	2025/03/25	rogid:3RdoEmgD0ZqhIsILQPNdDiNo1rg1334	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:1DA9C5F52936883C|rigid:7eteQ6LrU5rgbOOpTDkyANhBGJo	false	binding-associated region:1042-1066	binding-associated region:46-138	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P14738	uniprotkb:P02751	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Schwarz-Linek et al. (2003)	imex:IM-26856|pubmed:12736686	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20729941|imex:IM-26856-5	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	comment:mint	-	figure legend:Fig 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/16	2025/03/25	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:F481BE2CCDE2DF45|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	binding-associated region:531-549	binding-associated region:91-180	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P14738	uniprotkb:P02751	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Schwarz-Linek et al. (2003)	imex:IM-26856|pubmed:12736686	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20729946|imex:IM-26856-7	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	comment:mint	-	figure legend:Fig 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/16	2025/03/25	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:602B7E3DEB3A4F87|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	binding-associated region:837-858	binding-associated region:181-273	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P14738	uniprotkb:P02751	intact:EBI-8398157|intact:MINT-7991198|uniprotkb:Q2G1T8	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:fnba_staa8(display_long)|uniprotkb:fnbA(gene name)|psi-mi:fnbA(display_short)|uniprotkb:SAOUHSC_02803(locus name)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Schwarz-Linek et al. (2003)	imex:IM-26856|pubmed:12736686	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20729951|imex:IM-26856-9	intact-miscore:0.79	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0001968""(fibronectin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0098630""(aggregation of unicellular organisms)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR019931|interpro:IPR041171|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:4B5Z|rcsb pdb:4B60|refseq:YP_501262.1|refseq:WP_000794582.1|dip:DIP-46263N|mint:P14738|refseq:WP_011447070.1"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	comment:mint	-	figure legend:Fig 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/16	2025/03/25	rogid:4RGcezImp+nfT+g5uurgpGhEtpQ93061	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:EF8EA9E55ABAB816|rigid:442+mqVYF0Ve1UWi83jESkY07MM	false	binding-associated region:741-762	binding-associated region:91-180	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q01924	uniprotkb:P02751	intact:EBI-20729956	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q01924_strpy(display_long)|uniprotkb:Sfb(gene name)|psi-mi:Sfb(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Schwarz-Linek et al. (2003)	imex:IM-26856|pubmed:12736686	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20729964|imex:IM-26856-11	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR023849|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR013552(Fibronectin-binding, signal sequence)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:Fig 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/16	2025/03/25	rogid:Tx6NffQs013cRFmtAP3bP0vkRFY1314	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:121547F360CB0757|rigid:NwZ52OUrF3dT5y8Sk+xiYTd9CG0	false	binding-associated region:429-450	binding-associated region:181-273	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q01924	uniprotkb:P02751	intact:EBI-20729956	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q01924_strpy(display_long)|uniprotkb:Sfb(gene name)|psi-mi:Sfb(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Schwarz-Linek et al. (2003)	imex:IM-26856|pubmed:12736686	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20729974|imex:IM-26856-13	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR023849|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR013552(Fibronectin-binding, signal sequence)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:Fig 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/16	2025/03/25	rogid:Tx6NffQs013cRFmtAP3bP0vkRFY1314	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:5817D30B736A66AB|rigid:NwZ52OUrF3dT5y8Sk+xiYTd9CG0	false	binding-associated region:560-577	binding-associated region:91-180	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q01924	uniprotkb:P02751	intact:EBI-20729956	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q01924_strpy(display_long)|uniprotkb:Sfb(gene name)|psi-mi:Sfb(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Schwarz-Linek et al. (2003)	imex:IM-26856|pubmed:12736686	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20729979|imex:IM-26856-15	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR023849|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR013552(Fibronectin-binding, signal sequence)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:Fig 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/16	2025/03/25	rogid:Tx6NffQs013cRFmtAP3bP0vkRFY1314	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:4941CD067F8A379E|rigid:NwZ52OUrF3dT5y8Sk+xiYTd9CG0	false	binding-associated region:567-591	binding-associated region:46-138	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q01924	uniprotkb:P02751	intact:EBI-20729956	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q01924_strpy(display_long)|uniprotkb:Sfb(gene name)|psi-mi:Sfb(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Schwarz-Linek et al. (2003)	imex:IM-26856|pubmed:12736686	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20729984|imex:IM-26856-17	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR023849|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR013552(Fibronectin-binding, signal sequence)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:Fig 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/16	2025/03/25	rogid:Tx6NffQs013cRFmtAP3bP0vkRFY1314	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:C68F93008E417322|rigid:NwZ52OUrF3dT5y8Sk+xiYTd9CG0	false	binding-associated region:542-591	binding-associated region:46-273	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q01924	uniprotkb:P02751	intact:EBI-20729956	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q01924_strpy(display_long)|uniprotkb:Sfb(gene name)|psi-mi:Sfb(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Schwarz-Linek et al. (2003)	imex:IM-26856|pubmed:12736686	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-20729989|imex:IM-26856-19	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR023849|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR013552(Fibronectin-binding, signal sequence)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:Fig 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/08/16	2025/03/25	rogid:Tx6NffQs013cRFmtAP3bP0vkRFY1314	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:894503AC558DA2DB|rigid:NwZ52OUrF3dT5y8Sk+xiYTd9CG0	false	binding-associated region:431-467	binding-associated region:46-273	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q12866	uniprotkb:Q83FA5	intact:EBI-2804911|uniprotkb:Q9HBB4|ensembl:ENSP00000295408.4	intact:EBI-21284971	psi-mi:mertk_human(display_long)|uniprotkb:MER(gene name synonym)|uniprotkb:Proto-oncogene c-Mer(gene name synonym)|uniprotkb:Receptor tyrosine kinase MerTK(gene name synonym)|uniprotkb:MERTK(gene name)|psi-mi:MERTK(display_short)	psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21284983|imex:IM-26899-103	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000153208.19(gene)|ensembl:ENST00000295408.9(transcript)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001779""(natural killer cell differentiation)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006909""(phagocytosis)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007399""(nervous system development)|go:""GO:0008288""(boss receptor activity)|go:""GO:0016477""(cell migration)|go:""GO:0030168""(platelet activation)|go:""GO:0032940""(secretion by cell)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0043235""(receptor complex)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0051250""(negative regulation of lymphocyte activation)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0060068""(vagina development)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:2000107""(negative regulation of leukocyte apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036179|interpro:IPR050122|mint:Q12866|rcsb pdb:2DBJ|rcsb pdb:2P0C|rcsb pdb:3BPR|rcsb pdb:3BRB|rcsb pdb:3TCP|rcsb pdb:4M3Q|rcsb pdb:4MH7|rcsb pdb:4MHA|rcsb pdb:5K0K|rcsb pdb:5K0X|rcsb pdb:5TC0|rcsb pdb:5TD2|rcsb pdb:5U6C|rcsb pdb:6MEP|rcsb pdb:7AAX|rcsb pdb:7AAY|rcsb pdb:7AAZ|rcsb pdb:7AB0|rcsb pdb:7AB1|rcsb pdb:7AB2|rcsb pdb:7AVX|rcsb pdb:7AVY|rcsb pdb:7AVZ|rcsb pdb:7AW0|rcsb pdb:7AW1|rcsb pdb:7AW2|rcsb pdb:7AW3|rcsb pdb:7AW4|rcsb pdb:7CQE|rcsb pdb:7DXL|rcsb pdb:7M5Z|rcsb pdb:7OAM|rcsb pdb:7OLS|rcsb pdb:7OLV|rcsb pdb:7OLX|rcsb pdb:7XHY|rcsb pdb:9BHI|rcsb pdb:9BHJ|rcsb pdb:9BHK|reactome:R-HSA-202733|refseq:NP_006334.2|efo:""Orphanet:791""|ensembl:ENSP00000295408.4|panther:PTHR24416(orthology-group)"	mint:Q83FA5|refseq:NP_819096.1|refseq:WP_010957340.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:d1TXRqQHZG+X91BEM32fecg/0bU9606	rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377	intact-crc:E9DA32274F7D3E98|rigid:m4dbB/Ncfj5XqfnDBcy+sB6bT9s	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NZJ5	uniprotkb:Q83FA5	intact:EBI-766076|uniprotkb:A0AVH2|uniprotkb:A0AVH1|uniprotkb:B2RCU9|uniprotkb:Q53QY0|uniprotkb:Q53SB1|uniprotkb:O95846|ensembl:ENSP00000307235.3	intact:EBI-21284971	psi-mi:e2ak3_human(display_long)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)|uniprotkb:EIF2AK3(gene name)|psi-mi:EIF2AK3(display_short)|uniprotkb:PEK(gene name synonym)|uniprotkb:PERK(gene name synonym)|uniprotkb:Protein tyrosine kinase EIF2AK3(gene name synonym)	psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21284977|imex:IM-26899-101	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000172071.15(gene)|ensembl:ENST00000303236.9(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001503""(ossification)|go:""GO:0001525""(angiogenesis)|go:""GO:0002063""(chondrocyte development)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006983""(ER overload response)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010998""(regulation of translational initiation by eIF2 alpha phosphorylation)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030282""(bone mineralization)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031018""(endocrine pancreas development)|go:""GO:0031642""(negative regulation of myelination)|go:""GO:0032055""(negative regulation of translation in response to stress)|go:""GO:0032057""(negative regulation of translational initiation in response to stress)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036492""(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:""GO:0036499""(PERK-mediated unfolded protein response)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0045943""(positive regulation of transcription by RNA polymerase I)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0060734""(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:""GO:0070417""(cellular response to cold)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902235""(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990737""(response to manganese-induced endoplasmic reticulum stress)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050339|mint:Q9NZJ5|rcsb pdb:4G31|rcsb pdb:4G34|rcsb pdb:4M7I|rcsb pdb:4X7H|rcsb pdb:4X7J|rcsb pdb:4X7K|rcsb pdb:4X7L|rcsb pdb:4X7N|rcsb pdb:4X7O|rcsb pdb:4YZS|rcsb pdb:5SV7|rcsb pdb:7MF0|rcsb pdb:8EQ9|rcsb pdb:8EQD|rcsb pdb:8EQE|reactome:R-HSA-381042|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9755511|refseq:NP_004827.4|efo:""Orphanet:1667""|panther:PTHR11042(orthology-group)"	mint:Q83FA5|refseq:NP_819096.1|refseq:WP_010957340.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:sjPIYQzmbvq1fvSgn0HR781yf9w9606	rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377	intact-crc:8144BEE11463AB7B|rigid:K9LKn8FuvoGZY1xuRLgy+ArSpd0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P63146	uniprotkb:Q83F71	intact:EBI-712629|uniprotkb:P23567|uniprotkb:Q4PJ15|uniprotkb:Q9D0J6|uniprotkb:B2R503|uniprotkb:D3DQA2|ensembl:ENSP00000265339.2	intact:EBI-21284995	psi-mi:ube2b_human(display_long)|uniprotkb:Ubiquitin-protein ligase B(gene name synonym)|uniprotkb:Ubiquitin carrier protein B(gene name synonym)|uniprotkb:RAD6 homolog B(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa(gene name synonym)|uniprotkb:UBE2B(gene name)|psi-mi:UBE2B(display_short)|uniprotkb:RAD6B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme B(gene name synonym)|uniprotkb:UBCH1(gene name synonym)	psi-mi:q83f71_coxbu(display_long)|uniprotkb:CBU_0077(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285008|imex:IM-26899-1	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003328.1|ensembl:ENSG00000119048.9(gene)|ensembl:ENST00000265339.7(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000785""(chromatin)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001741""(XY body)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005657""(replication fork)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006301""(postreplication repair)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007288""(sperm axoneme assembly)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009411""(response to UV)|go:""GO:0010845""(positive regulation of reciprocal meiotic recombination)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0033503""(HULC complex)|go:""GO:0035234""(ectopic germ cell programmed cell death)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045141""(meiotic telomere clustering)|go:""GO:0050821""(protein stabilization)|go:""GO:0051026""(chiasma assembly)|go:""GO:0051093""(negative regulation of developmental process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070193""(synaptonemal complex organization)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:1901874""(negative regulation of post-translational protein modification)|go:""GO:2000242""(negative regulation of reproductive process)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR050113|mint:P63146|rcsb pdb:1JAS|rcsb pdb:2Y4W|rcsb pdb:2YB6|rcsb pdb:2YBF|reactome:R-HSA-110314|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|dip:DIP-29832N|panther:PTHR24067(orthology-group)"	"mint:Q83F71|go:""GO:0016020""(membrane)|refseq:NP_819130.1|refseq:WP_010957363.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:JvcUPH+3qQXicPsIRFnW19NOc3c9606	rogid:JKMfHyEgVdel7cHzOgnLRUH7JWo227377	intact-crc:ACFBE5EEDCE1F908|rigid:Fh16LEJbF/27rBzwUYgfNuwUxWk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P11310	uniprotkb:Q83F71	intact:EBI-514381|uniprotkb:Q9NYF1|uniprotkb:Q5T4U4|ensembl:ENSP00000359878.5	intact:EBI-21284995	psi-mi:acadm_human(display_long)|uniprotkb:Medium chain acyl-CoA dehydrogenase(gene name synonym)|uniprotkb:ACADM(gene name)|psi-mi:ACADM(display_short)	psi-mi:q83f71_coxbu(display_long)|uniprotkb:CBU_0077(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285002|imex:IM-26899-541	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:42""|ensembl:ENSG00000117054.15(gene)|ensembl:ENST00000370841.9(transcript)|go:""GO:0001889""(liver development)|go:""GO:0003995""(acyl-CoA dehydrogenase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005978""(glycogen biosynthetic process)|go:""GO:0006111""(regulation of gluconeogenesis)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0009409""(response to cold)|go:""GO:0009791""(post-embryonic development)|go:""GO:0019254""(carnitine metabolic process, CoA-linked)|go:""GO:0030424""(axon)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033539""(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:""GO:0042594""(response to starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045329""(carnitine biosynthetic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0051791""(medium-chain fatty acid metabolic process)|go:""GO:0051793""(medium-chain fatty acid catabolic process)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0070991""(medium-chain fatty acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|interpro:IPR046373|interpro:IPR050741|mint:P11310|rcsb pdb:1EGC|rcsb pdb:1EGD|rcsb pdb:1EGE|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:4P13|rcsb pdb:8SGP|reactome:R-HSA-1989781|reactome:R-HSA-77288|reactome:R-HSA-77346|reactome:R-HSA-77348|refseq:NP_000007.1|refseq:NP_001120800.1|panther:PTHR48083(orthology-group)|dip:DIP-34281N"	"mint:Q83F71|go:""GO:0016020""(membrane)|refseq:NP_819130.1|refseq:WP_010957363.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:rfmTmYKNQr6R6ikvfYovZIctoz49606	rogid:JKMfHyEgVdel7cHzOgnLRUH7JWo227377	intact-crc:84FE1F12203DB061|rigid:mME0wb4+1HJKUzL3WnxTQjAL+Co	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O60337	uniprotkb:Q820B6	intact:EBI-2684600|uniprotkb:A5PKZ4|uniprotkb:O14670|uniprotkb:Q86X77|uniprotkb:D3DTC8|intact:EBI-28971061|uniprotkb:B4DKJ2|uniprotkb:B4DT33|ensembl:ENSP00000274140.4	intact:EBI-21285020	psi-mi:marh6_human(display_long)|uniprotkb:MARCHF6(gene name)|psi-mi:MARCHF6(display_short)|uniprotkb:Doa10 homolog(gene name synonym)|uniprotkb:KIAA0597(gene name synonym)|uniprotkb:MARCH6(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 6(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein VI(gene name synonym)|uniprotkb:Protein TEB-4(gene name synonym)|uniprotkb:RING finger protein 176(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF6(gene name synonym)|uniprotkb:RNF176(gene name synonym)|uniprotkb:TEB4(gene name synonym)	psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285036|imex:IM-26899-3	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:86814""|dip:DIP-56134N|ensembl:ENSG00000145495.17(gene)|ensembl:ENST00000274140.10(transcript)|go:""GO:0000835""(ER ubiquitin ligase complex)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019899""(enzyme binding)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0036503""(ERAD pathway)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044322""(endoplasmic reticulum quality control compartment)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1904380""(endoplasmic reticulum mannose trimming)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O60337|reactome:R-HSA-901032|refseq:NP_001257589.1|refseq:NP_001257590.1|refseq:NP_005876.2|panther:PTHR13145(orthology-group)"	"mint:Q820B6|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/27	rogid:ow2W2xIcL82tgIHRS0SxlY4Ffjs9606	rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377	intact-crc:DE1F10E30108A8E5|rigid:rd+zFykkyOZ8tv+zGxg0mhZx9Qs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95388	uniprotkb:Q83F71	intact:EBI-1050638|uniprotkb:Q9HCS3|uniprotkb:A8KAG6|uniprotkb:Q5JBS8|uniprotkb:E7EMM5|uniprotkb:Q5JBS6|uniprotkb:Q5JBS7|ensembl:ENSP00000250160.5	intact:EBI-21284995	psi-mi:ccn4_human(display_long)|uniprotkb:CCN4(gene name)|psi-mi:CCN4(display_short)|uniprotkb:WISP1(gene name synonym)|uniprotkb:WNT1-inducible-signaling pathway protein 1(gene name synonym)|uniprotkb:Wnt-1-induced secreted protein(gene name synonym)	psi-mi:q83f71_coxbu(display_long)|uniprotkb:CBU_0077(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285014|imex:IM-26899-301	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191798.1|refseq:NP_003873.1|refseq:NP_543028.1|refseq:NP_001191799.1|ensembl:ENSG00000104415.14(gene)|ensembl:ENST00000250160.11(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0005178""(integrin binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008201""(heparin binding)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0060348""(bone development)|go:""GO:0090303""(positive regulation of wound healing)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR006208(Cystine knot)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012395(IGFBP-related, CNN)|interpro:IPR017891|interpro:IPR036383|interpro:IPR043973|interpro:IPR050941|mint:O95388|panther:PTHR11348(orthology-group)"	"mint:Q83F71|go:""GO:0016020""(membrane)|refseq:NP_819130.1|refseq:WP_010957363.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ZHPmZwRC/cRYTsWrXTLBoMZiI8k9606	rogid:JKMfHyEgVdel7cHzOgnLRUH7JWo227377	intact-crc:DE72AD6F0828122E|rigid:nsA/OP3BiXmldHJE7lQD8IXjd0U	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08758	uniprotkb:Q820B6	intact:EBI-296601|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|ensembl:ENSP00000296511.5|uniprotkb:D3DNW7	intact:EBI-21285020	psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym)	psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285030|imex:IM-26899-303	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001145.1|ensembl:ENSG00000164111.15(gene)|ensembl:ENST00000296511.10(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0004859""(phospholipase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007596""(blood coagulation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0050819""(negative regulation of coagulation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072563""(endothelial microparticle)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|rcsb pdb:8GYC|rcsb pdb:8H0J|rcsb pdb:8H9Z|reactome:R-HSA-114608|panther:PTHR10502(orthology-group)"	"mint:Q820B6|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606	rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377	intact-crc:C61BA973361E7354|rigid:aod9T7pvkEIgZefAST7fYrN+0ug	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6P4A8	uniprotkb:Q83FA5	intact:EBI-2861204|uniprotkb:Q9BVV3|uniprotkb:Q9H625|uniprotkb:A8K4E9|ensembl:ENSP00000240617.5	intact:EBI-21284971	psi-mi:plbl1_human(display_long)|uniprotkb:PLBD1(gene name)|psi-mi:PLBD1(display_short)|uniprotkb:LAMA-like protein 1(gene name synonym)|uniprotkb:Lamina ancestor homolog 1(gene name synonym)|uniprotkb:Phospholipase B domain-containing protein 1(gene name synonym)	psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21284989|imex:IM-26899-201	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079105.4|ensembl:ENSG00000121316.11(gene)|ensembl:ENST00000240617.10(transcript)|go:""GO:0004620""(phospholipase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005829""(cytosol)|go:""GO:0009395""(phospholipid catabolic process)|interpro:IPR007000(Laminin A)|interpro:IPR043040|interpro:IPR043041|interpro:IPR043042|mint:Q6P4A8|reactome:R-HSA-1482788|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1483115|panther:PTHR12370(orthology-group)"	mint:Q83FA5|refseq:NP_819096.1|refseq:WP_010957340.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:6ZbYKlwkiOBkyp3kckZ4QkLCj689606	rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377	intact-crc:26A0A3E3AE8C4733|rigid:iQAKggyD/1M0RcrA571j9OphqpE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P49257	uniprotkb:Q820B6	intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047.4|intact:EBI-21355115	intact:EBI-21285020	psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym)	psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285048|imex:IM-26899-321	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000074695.6(gene)|ensembl:ENST00000251047.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006457""(protein folding)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007596""(blood coagulation)|go:""GO:0010638""(positive regulation of organelle organization)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0030017""(sarcomere)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903215""(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR051136|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|rcsb pdb:8JP4|rcsb pdb:8JP5|rcsb pdb:8JP6|rcsb pdb:8JP7|rcsb pdb:8JP8|rcsb pdb:8JP9|rcsb pdb:8JPG|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-948021|refseq:NP_005561.1|efo:""Orphanet:35909""|dip:DIP-42188N|panther:PTHR12223(orthology-group)"	"mint:Q820B6|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/05	rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606	rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377	intact-crc:14D1CE8514E1992E|rigid:dTgVVUj5pJCREXZhGsgMOTy0rKk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P23515	uniprotkb:Q820B6	intact:EBI-20720752|ensembl:ENSP00000247271.4|ensembl:ENSP00000517225.1|uniprotkb:E1P659	intact:EBI-21285020	psi-mi:omgp_human(display_long)|uniprotkb:OMG(gene name)|psi-mi:OMG(display_short)|uniprotkb:OMGP(gene name synonym)	psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285054|imex:IM-26899-323	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000126861.5(gene)|ensembl:ENSG00000291720.1(gene)|ensembl:ENST00000247271.5(transcript)|ensembl:ENST00000708440.1(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0031102""(neuron projection regeneration)|go:""GO:0098552""(side of membrane)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR051071|mint:P23515|reactome:R-HSA-193634|refseq:NP_002535.3|panther:PTHR47114(orthology-group)"	"mint:Q820B6|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:tTKo2vTV2DB2ocBMyTnhwef0w+k9606	rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377	intact-crc:AC8365FFAF3BB582|rigid:r0Y+f1ANDfZ54Za/aDQzPkY0A1I	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P46782	uniprotkb:Q820B6	intact:EBI-350569|uniprotkb:Q96BN0|uniprotkb:B2R4T2|ensembl:ENSP00000196551.3|ensembl:ENSP00000470114.1|ensembl:ENSP00000472985.1|intact:EBI-21354748	intact:EBI-21285020	psi-mi:rs5_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)|uniprotkb:40S ribosomal protein S5(gene name synonym)	psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285066|imex:IM-26899-5	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001000.2|ensembl:ENSG00000083845.9(gene)|ensembl:ENST00000196551.8(transcript)|ensembl:ENST00000596046.1(transcript)|ensembl:ENST00000601521.5(transcript)|go:""GO:0000028""(ribosomal small subunit assembly)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0006413""(translational initiation)|go:""GO:0006450""(regulation of translational fidelity)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0032040""(small-subunit processome)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0045202""(synapse)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823|mint:P46782|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7WTT|rcsb pdb:7WTU|rcsb pdb:7WTV|rcsb pdb:7WTW|rcsb pdb:7WTX|rcsb pdb:7WTZ|rcsb pdb:7WU0|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9735869|reactome:R-HSA-9754678|reactome:R-HSA-975956|reactome:R-HSA-975957|panther:PTHR11205(orthology-group)"	"mint:Q820B6|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:SoCJdf2InngZZtlz5qD1k5CEfEo9606	rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377	intact-crc:2D4D2671AA5921D8|rigid:YUUvHygy9RkSNbX3mY4/s+77yec	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q93062	uniprotkb:Q820B6	intact:EBI-740322|uniprotkb:Q92516|uniprotkb:Q92517|uniprotkb:Q92518|uniprotkb:Q96J26|uniprotkb:D3DSU9|ensembl:ENSP00000318102.4|ensembl:ENSP00000380486.4	intact:EBI-21285020	psi-mi:rbpms_human(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285060|imex:IM-26899-441	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001008710.1|refseq:NP_001008711.1|refseq:NP_001008712.1|refseq:NP_006858.1|ensembl:ENSG00000157110.16(gene)|ensembl:ENST00000320203.8(transcript)|ensembl:ENST00000397323.9(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000932""(P-body)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0097157""(pre-mRNA intronic binding)|go:""GO:1990715""(mRNA CDS binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q93062|rcsb pdb:5CYJ|rcsb pdb:5DET|refseq:XP_016868475.1|panther:PTHR10501(orthology-group)"	"mint:Q820B6|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:3PsLJDzqs+19eVFeQlN+yLielYM9606	rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377	intact-crc:7AEBE24B81680612|rigid:uV56NwlhJbF17nUVpjz/yU1Zl4E	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NTM9	uniprotkb:Q820B6	intact:EBI-714918|uniprotkb:Q5TCZ8|uniprotkb:Q9Y321|ensembl:ENSP00000359507.5	intact:EBI-21285020	psi-mi:cutc_human(display_long)|uniprotkb:CUTC(gene name)|psi-mi:CUTC(display_short)|uniprotkb:CGI-32(orf name)	psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285042|imex:IM-26899-621	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057044.2|ensembl:ENSG00000119929.13(gene)|ensembl:ENST00000370476.10(transcript)|go:""GO:0005507""(copper ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006825""(copper ion transport)|go:""GO:0051262""(protein tetramerization)|go:""GO:0055070""(copper ion homeostasis)|interpro:IPR005627(CutC)|interpro:IPR036822|mint:Q9NTM9|rcsb pdb:3IWP|reactome:R-HSA-936837|panther:PTHR12598(orthology-group)"	"mint:Q820B6|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:MkxQTQ5IGq+/IZzPy3wSurdtB6w9606	rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377	intact-crc:99B10FEF90321D14|rigid:bcebAC2jLu5CACqhbTxp8UW8CiQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9C030	uniprotkb:Q820B6	intact:EBI-21285078|ensembl:ENSP00000278302.5|uniprotkb:A8K2A7|uniprotkb:B4DDQ5|uniprotkb:Q86WZ8|uniprotkb:Q9HCR1	intact:EBI-21285020	psi-mi:trim6_human(display_long)|uniprotkb:TRIM6(gene name)|psi-mi:TRIM6(display_short)|uniprotkb:RNF89(gene name synonym)|uniprotkb:RING finger protein 89(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM6(gene name synonym)	psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285143|imex:IM-26899-443	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000121236.21(gene)|ensembl:ENST00000278302.9(transcript)|go:""GO:0002230""(positive regulation of defense response to virus by host)|go:""GO:0002720""(positive regulation of cytokine production involved in immune response)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0010994""(free ubiquitin chain polymerization)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046596""(regulation of viral entry into host cell)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000679""(positive regulation of transcription regulatory region DNA binding)|go:""GO:2000737""(negative regulation of stem cell differentiation)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR035828|interpro:IPR043136|interpro:IPR050143|mint:Q9C030|reactome:R-HSA-877300|refseq:NP_001003818.1|refseq:NP_001185573.1|refseq:NP_001185574.1|refseq:NP_477514.1|panther:PTHR24103(orthology-group)"	"mint:Q820B6|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:7zeiA3CcNpnvDcv1wI+2jZRw+1Q9606	rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377	intact-crc:61ACD5C2EF460635|rigid:5C5bFPBMo+QQPPj5WZfh5b4pnkQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y5X3	uniprotkb:Q820B6	intact:EBI-715760|uniprotkb:Q52LC4|uniprotkb:B7ZKN3|uniprotkb:Q9BWP0|uniprotkb:D3DW26|uniprotkb:Q7KZN0|ensembl:ENSP00000366988.3|ensembl:ENSP00000366998.3	intact:EBI-21285020	psi-mi:snx5_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short)	psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285072|imex:IM-26899-721	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055241.1|refseq:NP_689413.1|ensembl:ENSG00000089006.17(gene)|ensembl:ENST00000377759.9(transcript)|ensembl:ENST00000377768.7(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001891""(phagocytic cup)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006907""(pinocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010314""(phosphatidylinositol-5-phosphate binding)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0034452""(dynactin binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0045776""(negative regulation of blood pressure)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070685""(macropinocytic cup)|go:""GO:0080025""(phosphatidylinositol-3,5-bisphosphate binding)|go:""GO:0097422""(tubular endosome)|go:""GO:0098559""(cytoplasmic side of early endosome membrane)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|interpro:IPR042135|mint:Q9Y5X3|rcsb pdb:1SYS|rcsb pdb:5TGH|rcsb pdb:5TGI|rcsb pdb:5TGJ|rcsb pdb:5WY2|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6N5Z|rcsb pdb:8A1G|rcsb pdb:8ABQ|rcsb pdb:8AFZ|reactome:R-HSA-432722|panther:PTHR45850(orthology-group)"	"mint:Q820B6|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:VR2oUxQ4M2bm5zKeHQlao046QL09606	rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377	intact-crc:15ACEDB27C7878A7|rigid:z4DrhUOs5WhDnxThcjrh4CsMcaM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P20020	uniprotkb:Q83DF6	intact:EBI-5279998|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|ensembl:ENSP00000392043.3	intact:EBI-21285191	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285206|imex:IM-26899-623	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000070961.17(gene)|efo:""Orphanet:528084""|ensembl:ENST00000428670.8(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0003056""(regulation of vascular associated smooth muscle contraction)|go:""GO:0005388""(P-type calcium transporter activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0015085""(calcium ion transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030501""(positive regulation of bone mineralization)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042995""(cell projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051481""(negative regulation of cytosolic calcium ion concentration)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098684""(photoreceptor ribbon synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1990034""(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P20020|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9662360|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_011536709.1|refseq:XP_016874847.1|panther:PTHR24093(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:C88A57DC7E494316|rigid:677j1EcJol8wZp4tJSBQye8NAvQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UGI8	uniprotkb:Q83E81	intact:EBI-2561654|uniprotkb:Q9HAJ9|uniprotkb:Q9GZQ1|uniprotkb:A4D0U6|ensembl:ENSP00000350937.4	intact:EBI-21285176	psi-mi:tes_human(display_long)|uniprotkb:TESS(gene name synonym)|uniprotkb:TES(gene name)|psi-mi:TES(display_short)	psi-mi:q83e81_coxbu(display_long)|uniprotkb:CBU_0447(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285185|imex:IM-26899-7	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056456.1|refseq:NP_690042.1|ensembl:ENSG00000135269.18(gene)|ensembl:ENST00000358204.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0030054""(cell junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045296""(cadherin binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR033724|interpro:IPR034958|interpro:IPR034959|interpro:IPR034960|interpro:IPR047120|mint:Q9UGI8|rcsb pdb:2IYB|rcsb pdb:2XQN|panther:PTHR24211(orthology-group)"	mint:Q83E81|interpro:IPR051165|refseq:NP_819484.1|refseq:WP_010957582.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770|panther:PTHR24193(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:19bO7/55OMgcMT5lx1404AluskE9606	rogid:sPpsju+FHsaThB3KcXKrHhNwlxc227377	intact-crc:4A1ED9AF4DECD6CD|rigid:Ebz7tVre6PTHjPZx/xsGyEtYm3s	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5VV63	uniprotkb:Q83DF6	intact:EBI-2682407|uniprotkb:Q6ZSN4|uniprotkb:Q6T256|uniprotkb:Q5JSE8|uniprotkb:Q86WX2|uniprotkb:O60283|uniprotkb:Q5T5Y9|intact:EBI-28971977|ensembl:ENSP00000347152.3	intact:EBI-21285191	psi-mi:atrn1_human(display_long)|uniprotkb:KIAA0534(gene name synonym)|uniprotkb:ATRNL1(gene name)|psi-mi:ATRNL1(display_short)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285218|imex:IM-26899-329	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_997186.1|refseq:NP_001263211.1|ensembl:ENSG00000107518.18(gene)|ensembl:ENST00000355044.8(transcript)|go:""GO:0005112""(Notch binding)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001304(C-type lectin)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR016201(Plexin-like fold)|interpro:IPR034011|interpro:IPR035914|interpro:IPR051568|mint:Q5VV63|panther:PTHR24044(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:4qYka2D3uDPSg1Fh6WBMMP1MLtE9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:77D4E92AE18C0912|rigid:IjASExPzoS0K+/XI+Soi9RiXQwE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95477	uniprotkb:Q83DF6	intact:EBI-784112|uniprotkb:Q96S56|uniprotkb:Q96T85|uniprotkb:Q9NQV4|uniprotkb:Q9UN06|uniprotkb:Q9UN07|uniprotkb:Q9UN08|uniprotkb:Q9UN09|uniprotkb:Q5VX33|ensembl:ENSP00000363868.3	intact:EBI-21285191	psi-mi:abca1_human(display_long)|uniprotkb:ATP-binding cassette transporter 1(gene name synonym)|uniprotkb:Cholesterol efflux regulatory protein(gene name synonym)|uniprotkb:ABCA1(gene name)|psi-mi:ABCA1(display_short)|uniprotkb:ABC1(gene name synonym)|uniprotkb:CERP(gene name synonym)|uniprotkb:ATP-binding cassette sub-family A member 1(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285200|imex:IM-26899-545	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-29211N|ensembl:ENSG00000165029.17(gene)|ensembl:ENST00000374736.8(transcript)|go:""GO:0002790""(peptide secretion)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005548""(phospholipid transporter activity)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007040""(lysosome organization)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0008035""(high-density lipoprotein particle binding)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0009306""(protein secretion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010745""(negative regulation of macrophage derived foam cell differentiation)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0010887""(negative regulation of cholesterol storage)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016197""(endosomal transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019905""(syntaxin binding)|go:""GO:0023061""(signal release)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032489""(regulation of Cdc42 protein signal transduction)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0033552""(response to vitamin B3)|go:""GO:0033700""(phospholipid efflux)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0034186""(apolipoprotein A-I binding)|go:""GO:0034188""(apolipoprotein A-I receptor activity)|go:""GO:0034380""(high-density lipoprotein particle assembly)|go:""GO:0034616""(response to laminar fluid shear stress)|go:""GO:0042158""(lipoprotein biosynthetic process)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043691""(reverse cholesterol transport)|go:""GO:0045121""(membrane raft)|go:""GO:0045332""(phospholipid translocation)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0046623""(sphingolipid floppase activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051117""(ATPase binding)|go:""GO:0055091""(phospholipid homeostasis)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071397""(cellular response to cholesterol)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0090107""(regulation of high-density lipoprotein particle assembly)|go:""GO:0090108""(positive regulation of high-density lipoprotein particle assembly)|go:""GO:0090554""(phosphatidylcholine floppase activity)|go:""GO:0090556""(phosphatidylserine floppase activity)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0120020""(cholesterol transfer activity)|go:""GO:0140115""(export across plasma membrane)|go:""GO:0140328""(floppase activity)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR026082|interpro:IPR027417|mint:O95477|rcsb pdb:5XJY|rcsb pdb:7ROQ|rcsb pdb:7TBW|rcsb pdb:7TBY|rcsb pdb:7TBZ|rcsb pdb:7TC0|rcsb pdb:7TDT|reactome:R-HSA-1989781|reactome:R-HSA-5682113|reactome:R-HSA-8963896|reactome:R-HSA-9029569|refseq:NP_005493.2|efo:""Orphanet:31150""|efo:""Orphanet:425""|panther:PTHR19229(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:DtErjp3P9x9wQEBDIbWae+OkfRc9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:DF0CB0829C947FB0|rigid:IPSxuxrYz9IcPrzN4UTw4Tf2Yag	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UIF8	uniprotkb:Q83EM2	intact:EBI-741542|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8|ensembl:ENSP00000376534.2	intact:EBI-21285149	psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym)	psi-mi:q83em2_coxbu(display_long)|uniprotkb:CBU_0295(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285157|imex:IM-26899-543	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_038478.2|refseq:NP_001276904.1|rcsb pdb:4CUP|rcsb pdb:4CUQ|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ7|rcsb pdb:5CQ6|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5E9Y|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBN|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|ensembl:ENSG00000123636.20(gene)|ensembl:ENST00000392783.7(transcript)|rcsb pdb:5PC9|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006338""(chromatin remodeling)|rcsb pdb:5PCA|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|rcsb pdb:5PCB|rcsb pdb:5PCC|go:""GO:0046872""(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PCG|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5PD2|rcsb pdb:5PD3|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PDX|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PEQ|rcsb pdb:5PER|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PFM|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|rcsb pdb:7Q42|rcsb pdb:7WIN|panther:PTHR45915(orthology-group)"	mint:Q83EM2|interpro:IPR050767|refseq:NP_819338.1|refseq:WP_010957484.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|panther:PTHR11102(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606	rogid:93t8PoA8XuYP8WAnEuBgVdP88/U227377	intact-crc:A632FA6D3AB3FF1D|rigid:I3j3qGhKibKQuwN0VT3U4jnDOBM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UIF8	uniprotkb:Q83DF6	intact:EBI-741542|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8|ensembl:ENSP00000376534.2	intact:EBI-21285191	psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285224|imex:IM-26899-331	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_038478.2|refseq:NP_001276904.1|rcsb pdb:4CUP|rcsb pdb:4CUQ|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ7|rcsb pdb:5CQ6|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5E9Y|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBN|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|ensembl:ENSG00000123636.20(gene)|ensembl:ENST00000392783.7(transcript)|rcsb pdb:5PC9|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006338""(chromatin remodeling)|rcsb pdb:5PCA|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|rcsb pdb:5PCB|rcsb pdb:5PCC|go:""GO:0046872""(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PCG|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5PD2|rcsb pdb:5PD3|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PDX|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PEQ|rcsb pdb:5PER|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PFM|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|rcsb pdb:7Q42|rcsb pdb:7WIN|panther:PTHR45915(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:4023DF5677CC00DC|rigid:QagPTBg/LibE4OUIFHkQkuJQD9Q	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y5K8	uniprotkb:Q83DF6	intact:EBI-2684998|uniprotkb:Q9Y688|uniprotkb:B2RE33|ensembl:ENSP00000216442.7|ensembl:ENSP00000451167.1	intact:EBI-21285191	psi-mi:vatd_human(display_long)|uniprotkb:ATP6M(gene name synonym)|uniprotkb:VATD(gene name synonym)|uniprotkb:V-ATPase 28 kDa accessory protein(gene name synonym)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)|uniprotkb:ATP6V1D(gene name)|psi-mi:ATP6V1D(display_short)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285212|imex:IM-26899-327	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057078.1|ensembl:ENSG00000100554.12(gene)|ensembl:ENST00000216442.12(transcript)|ensembl:ENST00000554087.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000221""(vacuolar proton-transporting V-type ATPase, V1 domain)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0035579""(specific granule membrane)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0051452""(intracellular pH reduction)|go:""GO:0060271""(cilium assembly)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0061795""(Golgi lumen acidification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0098850""(extrinsic component of synaptic vesicle membrane)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|mint:Q9Y5K8|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|rcsb pdb:7UNF|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|panther:PTHR11671(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:UBGjCKLxcq9lkUY/Vh6+Kr2i+uk9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:03E40D89054935AF|rigid:J1qgi+out/wNCLsFu3LFHdnayi8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99496	uniprotkb:Q83ED7	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480.3|ensembl:ENSP00000520426.1	intact:EBI-21285163	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:q83ed7_coxbu(display_long)|uniprotkb:CBU_0388(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285170|imex:IM-26899-325	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000121481.12(gene)|ensembl:ENST00000367510.8(transcript)|ensembl:ENST00000715230.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000791""(euchromatin)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001739""(sex chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0007281""(germ cell development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0010467""(gene expression)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0071339""(MLL1 complex)|go:""GO:0071535""(RING-like zinc finger domain binding)|go:""GO:0140862""(histone H2AK119 ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|rcsb pdb:8GRM|rcsb pdb:8PP7|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|panther:PTHR46076(orthology-group)"	"mint:Q83ED7|go:""GO:0042025""(host cell nucleus)|refseq:NP_819427.1|refseq:WP_010957544.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/27	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:szWBjlt2UW4YQjhWye714QtnMk4227377	intact-crc:6096A475AFC6A053|rigid:Ho5LrArnwW9fMnkxxZKQ1n5ydtI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75936	uniprotkb:Q83DF6	intact:EBI-715662|uniprotkb:Q6IBJ2|uniprotkb:B2R8L7|uniprotkb:D3DQZ1|ensembl:ENSP00000263182.3|ensembl:ENSP00000433772.1|ensembl:ENSP00000434918.1|ensembl:ENSP00000435781.1	intact:EBI-21285191	psi-mi:bodg_human(display_long)|uniprotkb:Gamma-butyrobetaine,2-oxoglutarate dioxygenase(gene name synonym)|uniprotkb:Gamma-butyrobetaine hydroxylase(gene name synonym)|uniprotkb:BBOX1(gene name)|psi-mi:BBOX1(display_short)|uniprotkb:BBH(gene name synonym)|uniprotkb:BBOX(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285230|imex:IM-26899-641	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003977.1|refseq:XP_005253216.1|refseq:XP_005253217.1|refseq:XP_005253218.1|refseq:XP_011518704.1|refseq:XP_016873892.1|ensembl:ENSG00000129151.9(gene)|ensembl:ENST00000263182.8(transcript)|ensembl:ENST00000525090.1(transcript)|ensembl:ENST00000528583.5(transcript)|ensembl:ENST00000529202.5(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008336""(gamma-butyrobetaine dioxygenase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0045329""(carnitine biosynthetic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR010376(Protein of unknown function DUF971)|interpro:IPR012775(Gamma-butyrobetaine,2-oxoglutarate dioxygenase)|interpro:IPR038492|interpro:IPR042098|interpro:IPR050411|mint:O75936|rcsb pdb:3MS5|rcsb pdb:3N6W|rcsb pdb:3O2G|rcsb pdb:4BG1|rcsb pdb:4BGK|rcsb pdb:4BGM|rcsb pdb:4BHF|rcsb pdb:4BHG|rcsb pdb:4BHI|rcsb pdb:4C5W|rcsb pdb:4C8R|rcsb pdb:4CWD|reactome:R-HSA-71262|panther:PTHR10696(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:oEjzTzRRvj9ygqEj2pca6MxK1Jo9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:01397820244D537B|rigid:voSMywqU1l/hNmm0ZYi9fBibqzc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y6G5	uniprotkb:Q83DF6	intact:EBI-1550310|uniprotkb:Q9P077|uniprotkb:D3DT07|ensembl:ENSP00000274458.4	intact:EBI-21285191	psi-mi:comda_human(display_long)|uniprotkb:COMMD10(gene name)|psi-mi:COMMD10(display_short)|uniprotkb:HSPC305(orf name)|uniprotkb:PTD002(orf name)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285248|imex:IM-26899-643	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057228.1|refseq:NP_001295009.1|ensembl:ENSG00000145781.9(gene)|ensembl:ENST00000274458.9(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|interpro:IPR017920|interpro:IPR037361|mint:Q9Y6G5|rcsb pdb:8ESD|rcsb pdb:8F2R|rcsb pdb:8F2U|rcsb pdb:8P0W|reactome:R-HSA-8951664|panther:PTHR12333(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:yRozKabxLJMAEbM9QfLGOQCzRxE9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:642D8306E4F7D186|rigid:4UKp1/AC9Y+jJsERxnVtKp8xW4g	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P10515	uniprotkb:Q83DF6	intact:EBI-2959723|uniprotkb:Q16783|uniprotkb:Q53EP3|ensembl:ENSP00000280346.7|ensembl:ENSP00000518862.1	intact:EBI-21285191	psi-mi:odp2_human(display_long)|uniprotkb:DLAT(gene name)|psi-mi:DLAT(display_short)|uniprotkb:DLTA(gene name synonym)|uniprotkb:70 kDa mitochondrial autoantigen of primary biliary cirrhosis(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:M2 antigen complex 70 kDa subunit(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285260|imex:IM-26899-547	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-29496N|ensembl:ENSG00000150768.18(gene)|ensembl:ENST00000280346.11(transcript)|ensembl:ENST00000713569.1(transcript)|go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006086""(pyruvate decarboxylation to acetyl-CoA)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045254""(pyruvate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|interpro:IPR045257|mint:P10515|rcsb pdb:1FYC|rcsb pdb:1Y8N|rcsb pdb:1Y8O|rcsb pdb:1Y8P|rcsb pdb:2DNE|rcsb pdb:2PNR|rcsb pdb:2Q8I|rcsb pdb:3B8K|rcsb pdb:3CRK|rcsb pdb:3CRL|rcsb pdb:6CT0|rcsb pdb:6H55|rcsb pdb:8PIU|reactome:R-HSA-204174|reactome:R-HSA-5362517|reactome:R-HSA-9857492|reactome:R-HSA-9861559|refseq:NP_001922.2|efo:""Orphanet:79244""|panther:PTHR23151(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/10	rogid:Owh80Cm4CXvo2rPKUhLGc/U47co9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:5ACFF22CDBF941DB|rigid:F4s1DOT6hDDJbWJqw5RjKY/tTHg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O94921	uniprotkb:Q83DF6	intact:EBI-1043945|uniprotkb:Q75N06|uniprotkb:Q75N22|uniprotkb:Q8N764|uniprotkb:Q9H3D7|uniprotkb:Q9UDR0|uniprotkb:A6NK51|uniprotkb:A4D1E6|uniprotkb:A8WFP6|uniprotkb:B4DHG5|uniprotkb:B4DNM2|ensembl:ENSP00000369390.3	intact:EBI-21285191	psi-mi:cdk14_human(display_long)|uniprotkb:CDK14(gene name)|psi-mi:CDK14(display_short)|uniprotkb:KIAA0834(gene name synonym)|uniprotkb:PFTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PFTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 14(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285242|imex:IM-26899-333	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036527.1|refseq:XP_005250495.1|refseq:XP_005250496.1|refseq:NP_001274064.1|refseq:NP_001274065.1|refseq:NP_001274066.1|refseq:XP_011514608.1|ensembl:ENSG00000058091.17(gene)|ensembl:ENST00000380050.8(transcript)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000307""(cyclin-dependent protein kinase holoenzyme complex)|go:""GO:0000308""(cytoplasmic cyclin-dependent protein kinase holoenzyme complex)|go:""GO:0004693""(cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030332""(cyclin binding)|go:""GO:0051301""(cell division)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1901987""(regulation of cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050108|mint:O94921|refseq:XP_016867809.1|refseq:XP_016867810.1|refseq:XP_016867811.1|dip:DIP-39618N|panther:PTHR24056(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:7qBB2uRgR1pz0G9qLYJ7i+GGMuk9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:CD13B5A76B49411C|rigid:o61UukmNpy5eB7jwBjGnd7M3y6Q	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00918	uniprotkb:Q83DF6	intact:EBI-724062|uniprotkb:Q6FI12|uniprotkb:Q96ET9|uniprotkb:B2R7G8|ensembl:ENSP00000285379.4	intact:EBI-21285191	psi-mi:cah2_human(display_long)|uniprotkb:Carbonic anhydrase II(gene name synonym)|uniprotkb:Carbonate dehydratase II(gene name synonym)|uniprotkb:Carbonic anhydrase C(gene name synonym)|uniprotkb:CA2(gene name)|psi-mi:CA2(display_short)|uniprotkb:Cyanamide hydratase CA2(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285236|imex:IM-26899-105	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2785""|ensembl:ENSG00000104267.10(gene)|ensembl:ENST00000285379.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0004064""(arylesterase activity)|go:""GO:0004089""(carbonate dehydratase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0015670""(carbon dioxide transport)|go:""GO:0018820""(cyanamide hydratase activity)|go:""GO:0032230""(positive regulation of synaptic transmission, GABAergic)|go:""GO:0032849""(positive regulation of cellular pH reduction)|go:""GO:0038166""(angiotensin-activated signaling pathway)|go:""GO:0043209""(myelin sheath)|go:""GO:0044070""(regulation of monoatomic anion transport)|go:""GO:0045177""(apical part of cell)|go:""GO:0046903""(secretion)|go:""GO:0051453""(regulation of intracellular pH)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:2001150""(positive regulation of dipeptide transmembrane transport)|go:""GO:2001225""(regulation of chloride transport)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR018338|interpro:IPR023561|interpro:IPR036398|mint:P00918|rcsb pdb:12CA|rcsb pdb:1A42|rcsb pdb:1AM6|rcsb pdb:1AVN|rcsb pdb:1BCD|rcsb pdb:1BIC|rcsb pdb:1BN1|rcsb pdb:1BN3|rcsb pdb:1BN4|rcsb pdb:1BNM|rcsb pdb:1BNN|rcsb pdb:1BNQ|rcsb pdb:1BNT|rcsb pdb:1BNU|rcsb pdb:1BNV|rcsb pdb:1BNW|rcsb pdb:1BV3|rcsb pdb:1CA2|rcsb pdb:1CA3|rcsb pdb:1CAH|rcsb pdb:1CAI|rcsb pdb:1CAJ|rcsb pdb:1CAK|rcsb pdb:1CAL|rcsb pdb:1CAM|rcsb pdb:1CAN|rcsb pdb:1CAO|rcsb pdb:1CAY|rcsb pdb:1CAZ|rcsb pdb:1CCS|rcsb pdb:1CCT|rcsb pdb:1CCU|rcsb pdb:1CIL|rcsb pdb:1CIM|rcsb pdb:1CIN|rcsb pdb:1CNB|rcsb pdb:1CNC|rcsb pdb:1CNG|rcsb pdb:1CNH|rcsb pdb:1CNI|rcsb pdb:1CNJ|rcsb pdb:1CNK|rcsb pdb:1CNW|rcsb pdb:1CNX|rcsb pdb:1CNY|rcsb pdb:1CRA|rcsb pdb:1CVA|rcsb pdb:1CVB|rcsb pdb:1CVC|rcsb pdb:1CVD|rcsb pdb:1CVE|rcsb pdb:1CVF|rcsb pdb:1CVH|rcsb pdb:1DCA|rcsb pdb:1DCB|rcsb pdb:1EOU|rcsb pdb:1F2W|rcsb pdb:1FQL|rcsb pdb:1FQM|rcsb pdb:1FQN|rcsb pdb:1FQR|rcsb pdb:1FR4|rcsb pdb:1FR7|rcsb pdb:1FSN|rcsb pdb:1FSQ|rcsb pdb:1FSR|rcsb pdb:1G0E|rcsb pdb:1G0F|rcsb pdb:1G1D|rcsb pdb:1G3Z|rcsb pdb:1G45|rcsb pdb:1G46|rcsb pdb:1G48|rcsb pdb:1G4J|rcsb pdb:1G4O|rcsb pdb:1G52|rcsb pdb:1G53|rcsb pdb:1G54|rcsb pdb:1H4N|rcsb pdb:1H9N|rcsb pdb:1H9Q|rcsb pdb:1HCA|rcsb pdb:1HEA|rcsb pdb:1HEB|rcsb pdb:1HEC|rcsb pdb:1HED|rcsb pdb:1HVA|rcsb pdb:1I8Z|rcsb pdb:1I90|rcsb pdb:1I91|rcsb pdb:1I9L|rcsb pdb:1I9M|rcsb pdb:1I9N|rcsb pdb:1I9O|rcsb pdb:1I9P|rcsb pdb:1I9Q|rcsb pdb:1IF4|rcsb pdb:1IF5|rcsb pdb:1IF6|rcsb pdb:1IF7|rcsb pdb:1IF8|rcsb pdb:1IF9|rcsb pdb:1KWQ|rcsb pdb:1KWR|rcsb pdb:1LG5|rcsb pdb:1LG6|rcsb pdb:1LGD|rcsb pdb:1LUG|rcsb pdb:1LZV|rcsb pdb:1MOO|rcsb pdb:1MUA|rcsb pdb:1OKL|rcsb pdb:1OKM|rcsb pdb:1OKN|rcsb pdb:1OQ5|rcsb pdb:1RAY|rcsb pdb:1RAZ|rcsb pdb:1RZA|rcsb pdb:1RZB|rcsb pdb:1RZC|rcsb pdb:1RZD|rcsb pdb:1RZE|rcsb pdb:1T9N|rcsb pdb:1TB0|rcsb pdb:1TBT|rcsb pdb:1TE3|rcsb pdb:1TEQ|rcsb pdb:1TEU|rcsb pdb:1TG3|rcsb pdb:1TG9|rcsb pdb:1TH9|rcsb pdb:1THK|rcsb pdb:1TTM|rcsb pdb:1UGA|rcsb pdb:1UGB|rcsb pdb:1UGC|rcsb pdb:1UGD|rcsb pdb:1UGE|rcsb pdb:1UGF|rcsb pdb:1UGG|rcsb pdb:1XEG|rcsb pdb:1XEV|rcsb pdb:1XPZ|rcsb pdb:1XQ0|rcsb pdb:1YDA|rcsb pdb:1YDB|rcsb pdb:1YDC|rcsb pdb:1YDD|rcsb pdb:1YO0|rcsb pdb:1YO1|rcsb pdb:1YO2|rcsb pdb:1Z9Y|rcsb pdb:1ZE8|rcsb pdb:1ZSC|rcsb pdb:1ZFK|rcsb pdb:1ZFQ|rcsb pdb:1ZGE|rcsb pdb:1ZGF|rcsb pdb:1ZH9|rcsb pdb:1ZSA|rcsb pdb:1ZSB|rcsb pdb:2ABE|rcsb pdb:2AW1|rcsb pdb:2AX2|rcsb pdb:2CA2|rcsb pdb:2CBA|rcsb pdb:2CBB|rcsb pdb:2CBC|rcsb pdb:2CBD|rcsb pdb:2CBE|rcsb pdb:2EU2|rcsb pdb:2EU3|rcsb pdb:2EZ7|rcsb pdb:2F14|rcsb pdb:2FMG|rcsb pdb:2FMZ|rcsb pdb:2FNK|rcsb pdb:2FNM|rcsb pdb:2FNN|rcsb pdb:2FOQ|rcsb pdb:2FOS|rcsb pdb:2FOU|rcsb pdb:2FOV|rcsb pdb:2GD8|rcsb pdb:2GEH|rcsb pdb:2H15|rcsb pdb:2H4N|rcsb pdb:2HD6|rcsb pdb:2HKK|rcsb pdb:2HL4|rcsb pdb:2HNC|rcsb pdb:2HOC|rcsb pdb:2QP6|rcsb pdb:2ILI|rcsb pdb:2NNG|rcsb pdb:2NNO|rcsb pdb:2NNS|rcsb pdb:2NNV|rcsb pdb:2NWO|rcsb pdb:2NWP|rcsb pdb:2NWY|rcsb pdb:2NWZ|rcsb pdb:2NXR|rcsb pdb:2NXS|rcsb pdb:2NXT|rcsb pdb:2O4Z|rcsb pdb:2OSF|rcsb pdb:2OSM|rcsb pdb:2POU|rcsb pdb:2POV|rcsb pdb:2POW|rcsb pdb:2Q1B|rcsb pdb:2Q1Q|rcsb pdb:2Q38|rcsb pdb:2QO8|rcsb pdb:2QOA|rcsb pdb:2VVA|rcsb pdb:2VVB|rcsb pdb:2WD2|rcsb pdb:2WD3|rcsb pdb:2WEG|rcsb pdb:2WEH|rcsb pdb:2WEJ|rcsb pdb:2WEO|rcsb pdb:2X7S|rcsb pdb:2X7T|rcsb pdb:2X7U|rcsb pdb:3B4F|rcsb pdb:3BET|rcsb pdb:3BL0|rcsb pdb:3BL1|rcsb pdb:3C7P|rcsb pdb:3CA2|rcsb pdb:3CAJ|rcsb pdb:3CYU|rcsb pdb:3D8W|rcsb pdb:3D92|rcsb pdb:3D93|rcsb pdb:3D9Z|rcsb pdb:3DAZ|rcsb pdb:3DBU|rcsb pdb:3DC3|rcsb pdb:3DC9|rcsb pdb:3DCC|rcsb pdb:3DCS|rcsb pdb:3DCW|rcsb pdb:3DD0|rcsb pdb:3DD8|rcsb pdb:3DV7|rcsb pdb:3DVB|rcsb pdb:3DVC|rcsb pdb:3DVD|rcsb pdb:3EFI|rcsb pdb:3EFT|rcsb pdb:3F4X|rcsb pdb:3F8E|rcsb pdb:3FFP|rcsb pdb:3GZ0|rcsb pdb:3HFP|rcsb pdb:3HKN|rcsb pdb:3HKQ|rcsb pdb:3HKT|rcsb pdb:3HKU|rcsb pdb:3HLJ|rcsb pdb:3HS4|rcsb pdb:3IBI|rcsb pdb:3IBL|rcsb pdb:3IBN|rcsb pdb:3IBU|rcsb pdb:3IEO|rcsb pdb:3IGP|rcsb pdb:3K2F|rcsb pdb:3K34|rcsb pdb:3K7K|rcsb pdb:3KIG|rcsb pdb:3KKX|rcsb pdb:3KNE|rcsb pdb:3KOI|rcsb pdb:3KOK|rcsb pdb:3KON|rcsb pdb:3KS3|rcsb pdb:3KWA|rcsb pdb:3L14|rcsb pdb:3M04|rcsb pdb:3M14|rcsb pdb:3M1J|rcsb pdb:3M1K|rcsb pdb:3M1Q|rcsb pdb:3M1W|rcsb pdb:3M2N|rcsb pdb:3M2X|rcsb pdb:3M2Y|rcsb pdb:3M2Z|rcsb pdb:3M3X|rcsb pdb:3M40|rcsb pdb:3M5E|rcsb pdb:3M5S|rcsb pdb:3M5T|rcsb pdb:3M67|rcsb pdb:3M96|rcsb pdb:3M98|rcsb pdb:3MHC|rcsb pdb:3MHI|rcsb pdb:3MHL|rcsb pdb:3MHM|rcsb pdb:3MHO|rcsb pdb:3ML2|rcsb pdb:3MMF|rcsb pdb:3MNA|rcsb pdb:3MNH|rcsb pdb:3MNI|rcsb pdb:3MNJ|rcsb pdb:3MNK|rcsb pdb:3MNU|rcsb pdb:3MWO|rcsb pdb:3MYQ|rcsb pdb:3MZC|rcsb pdb:3N0N|rcsb pdb:3N2P|rcsb pdb:3N3J|rcsb pdb:3N4B|rcsb pdb:3NB5|rcsb pdb:3NI5|rcsb pdb:3NJ9|rcsb pdb:3OIK|rcsb pdb:3OIL|rcsb pdb:3OIM|rcsb pdb:3OKU|rcsb pdb:3OKV|rcsb pdb:3OY0|rcsb pdb:3OYQ|rcsb pdb:3OYS|rcsb pdb:3P3H|rcsb pdb:3P3J|rcsb pdb:3P44|rcsb pdb:3P4V|rcsb pdb:3P55|rcsb pdb:3P58|rcsb pdb:3P5A|rcsb pdb:3P5L|rcsb pdb:3PJJ|rcsb pdb:3PO6|rcsb pdb:3PYK|rcsb pdb:3QYK|rcsb pdb:3R16|rcsb pdb:3R17|rcsb pdb:3RG3|rcsb pdb:3RG4|rcsb pdb:3RGE|rcsb pdb:3RJ7|rcsb pdb:3RLD|rcsb pdb:3RYJ|rcsb pdb:3RYV|rcsb pdb:3RYX|rcsb pdb:3RYY|rcsb pdb:3RYZ|rcsb pdb:3RZ0|rcsb pdb:3RZ1|rcsb pdb:3RZ5|rcsb pdb:3RZ7|rcsb pdb:3RZ8|rcsb pdb:3S71|rcsb pdb:3S72|rcsb pdb:3S73|rcsb pdb:3S74|rcsb pdb:3S75|rcsb pdb:3S76|rcsb pdb:3S77|rcsb pdb:3S78|rcsb pdb:3S8X|rcsb pdb:3S9T|rcsb pdb:3SAP|rcsb pdb:3SAX|rcsb pdb:3SBH|rcsb pdb:3SBI|rcsb pdb:3T5U|rcsb pdb:3T5Z|rcsb pdb:3T82|rcsb pdb:3T83|rcsb pdb:3T84|rcsb pdb:3T85|rcsb pdb:3TMJ|rcsb pdb:3TVN|rcsb pdb:3TVO|rcsb pdb:3U3A|rcsb pdb:3U45|rcsb pdb:3U47|rcsb pdb:3U7C|rcsb pdb:3V2J|rcsb pdb:3V2M|rcsb pdb:3V3F|rcsb pdb:3V3G|rcsb pdb:3V3H|rcsb pdb:3V3I|rcsb pdb:3V3J|rcsb pdb:3V5G|rcsb pdb:3V7X|rcsb pdb:3VBD|rcsb pdb:3ZP9|rcsb pdb:4BCW|rcsb pdb:4BF1|rcsb pdb:4BF6|rcsb pdb:4CA2|rcsb pdb:4CAC|rcsb pdb:4CQ0|rcsb pdb:4DZ7|rcsb pdb:4DZ9|rcsb pdb:4E3D|rcsb pdb:4E3F|rcsb pdb:4E3G|rcsb pdb:4E3H|rcsb pdb:4E49|rcsb pdb:4E4A|rcsb pdb:4E5Q|rcsb pdb:4FIK|rcsb pdb:4FL7|rcsb pdb:4FPT|rcsb pdb:4FRC|rcsb pdb:4FU5|rcsb pdb:4FVN|rcsb pdb:4FVO|rcsb pdb:4G0C|rcsb pdb:4GL1|rcsb pdb:4HBA|rcsb pdb:4HEW|rcsb pdb:4HEY|rcsb pdb:4HEZ|rcsb pdb:4HF3|rcsb pdb:4HT0|rcsb pdb:4IDR|rcsb pdb:4ILX|rcsb pdb:4ITO|rcsb pdb:4ITP|rcsb pdb:4IWZ|rcsb pdb:4JS6|rcsb pdb:4JSA|rcsb pdb:4JSS|rcsb pdb:4JSW|rcsb pdb:4JSZ|rcsb pdb:4K0S|rcsb pdb:4K0T|rcsb pdb:4K0Z|rcsb pdb:4K13|rcsb pdb:4K1Q|rcsb pdb:4KAP|rcsb pdb:4KNI|rcsb pdb:4KNJ|rcsb pdb:4KUV|rcsb pdb:4KUW|rcsb pdb:4KUY|rcsb pdb:4KV0|rcsb pdb:4L5U|rcsb pdb:4L5V|rcsb pdb:4L5W|rcsb pdb:4LHI|rcsb pdb:4LP6|rcsb pdb:4M2R|rcsb pdb:4M2U|rcsb pdb:4M2V|rcsb pdb:4M2W|rcsb pdb:4MDG|rcsb pdb:4MDL|rcsb pdb:4MDM|rcsb pdb:4MLT|rcsb pdb:4MLX|rcsb pdb:4MO8|rcsb pdb:4MTY|rcsb pdb:4N0X|rcsb pdb:4N16|rcsb pdb:4PQ7|rcsb pdb:4PXX|rcsb pdb:4PYX|rcsb pdb:4PYY|rcsb pdb:4PZH|rcsb pdb:4Q06|rcsb pdb:4Q07|rcsb pdb:4Q08|rcsb pdb:4Q09|rcsb pdb:4Q49|rcsb pdb:4Q6D|rcsb pdb:4Q6E|rcsb pdb:4Q78|rcsb pdb:4Q7P|rcsb pdb:4Q7S|rcsb pdb:4Q7V|rcsb pdb:4Q7W|rcsb pdb:4Q81|rcsb pdb:4Q83|rcsb pdb:4Q87|rcsb pdb:4Q8X|rcsb pdb:4Q8Y|rcsb pdb:4Q8Z|rcsb pdb:4Q90|rcsb pdb:4Q99|rcsb pdb:4Q9Y|rcsb pdb:4QEF|rcsb pdb:4QIY|rcsb pdb:4QJM|rcsb pdb:4QK1|rcsb pdb:4QK2|rcsb pdb:4QK3|rcsb pdb:4QSA|rcsb pdb:4QSB|rcsb pdb:4QSI|rcsb pdb:4QTL|rcsb pdb:4QY3|rcsb pdb:4R59|rcsb pdb:4R5A|rcsb pdb:4R5B|rcsb pdb:4RFC|rcsb pdb:4RFD|rcsb pdb:4RH2|rcsb pdb:4RIU|rcsb pdb:4RIV|rcsb pdb:4RN4|rcsb pdb:4RUX|rcsb pdb:4RUY|rcsb pdb:4RUZ|rcsb pdb:4WL4|rcsb pdb:4WW6|rcsb pdb:4XE1|rcsb pdb:4Y0J|rcsb pdb:4YGJ|rcsb pdb:4YGK|rcsb pdb:4YGL|rcsb pdb:4YGN|rcsb pdb:4YVY|rcsb pdb:4YWP|rcsb pdb:4YX4|rcsb pdb:4YXI|rcsb pdb:4YXO|rcsb pdb:4YXU|rcsb pdb:4YYT|rcsb pdb:4Z0Q|rcsb pdb:4Z1E|rcsb pdb:4Z1J|rcsb pdb:4Z1K|rcsb pdb:4Z1N|rcsb pdb:4ZAO|rcsb pdb:4ZWI|rcsb pdb:4ZWX|rcsb pdb:4ZWY|rcsb pdb:4ZWZ|rcsb pdb:4ZX0|rcsb pdb:4ZX1|rcsb pdb:5A6H|rcsb pdb:5AMD|rcsb pdb:5AMG|rcsb pdb:5AML|rcsb pdb:5BNL|rcsb pdb:5BRU|rcsb pdb:5BRV|rcsb pdb:5BRW|rcsb pdb:5BYI|rcsb pdb:5C8I|rcsb pdb:5CA2|rcsb pdb:5CAC|rcsb pdb:5CLU|rcsb pdb:5DOG|rcsb pdb:5DOH|rcsb pdb:5DRS|rcsb pdb:5DSK|rcsb pdb:5DSL|rcsb pdb:5DSM|rcsb pdb:5DSO|rcsb pdb:5DSP|rcsb pdb:5DSQ|rcsb pdb:5DSR|rcsb pdb:5E28|rcsb pdb:5E2K|rcsb pdb:5E2R|rcsb pdb:5E2S|rcsb pdb:5EH5|rcsb pdb:5EH7|rcsb pdb:5EH8|rcsb pdb:5EHE|rcsb pdb:5EHV|rcsb pdb:5EHW|rcsb pdb:5EIJ|rcsb pdb:5EKH|rcsb pdb:5EKJ|rcsb pdb:5EKM|rcsb pdb:5EOI|rcsb pdb:5FDC|rcsb pdb:5FDI|rcsb pdb:5FLO|rcsb pdb:5FLP|rcsb pdb:5FLQ|rcsb pdb:5FLR|rcsb pdb:5FLS|rcsb pdb:5FLT|rcsb pdb:5FNG|rcsb pdb:5FNH|rcsb pdb:5FNI|rcsb pdb:5FNJ|rcsb pdb:5FNK|rcsb pdb:5FNL|rcsb pdb:5FNM|rcsb pdb:5G01|rcsb pdb:5G03|rcsb pdb:5G0B|rcsb pdb:5G0C|rcsb pdb:5GMN|rcsb pdb:5J8Z|rcsb pdb:5JDV|rcsb pdb:5JE7|rcsb pdb:5JEG|rcsb pdb:5JEH|rcsb pdb:5JEP|rcsb pdb:5JES|rcsb pdb:5JG3|rcsb pdb:5JG5|rcsb pdb:5JGS|rcsb pdb:5JGT|rcsb pdb:5JMZ|rcsb pdb:5JN3|rcsb pdb:5JN7|rcsb pdb:5JQ0|rcsb pdb:5JQT|rcsb pdb:5L3O|rcsb pdb:5L6K|rcsb pdb:5L6T|rcsb pdb:5L70|rcsb pdb:5L9E|rcsb pdb:5LJQ|rcsb pdb:5LJT|rcsb pdb:5LL4|rcsb pdb:5LL8|rcsb pdb:5LLC|rcsb pdb:5LLE|rcsb pdb:5LLG|rcsb pdb:5LLH|rcsb pdb:5LMD|rcsb pdb:5LVS|rcsb pdb:5M78|rcsb pdb:5MJN|rcsb pdb:5N0D|rcsb pdb:5N0E|rcsb pdb:5N1R|rcsb pdb:5N1S|rcsb pdb:5N24|rcsb pdb:5N25|rcsb pdb:5NEA|rcsb pdb:5NEE|rcsb pdb:5NXG|rcsb pdb:5NXI|rcsb pdb:5NXM|rcsb pdb:5NXO|rcsb pdb:5NXP|rcsb pdb:5NXV|rcsb pdb:5NXW|rcsb pdb:5NY1|rcsb pdb:5NY3|rcsb pdb:5NY6|rcsb pdb:5NYA|rcsb pdb:5O07|rcsb pdb:5OGN|rcsb pdb:5OGO|rcsb pdb:5OGP|rcsb pdb:5SZ0|rcsb pdb:5SZ1|rcsb pdb:5SZ2|rcsb pdb:5SZ3|rcsb pdb:5SZ4|rcsb pdb:5SZ5|rcsb pdb:5SZ6|rcsb pdb:5SZ7|rcsb pdb:5T71|rcsb pdb:5T72|rcsb pdb:5T74|rcsb pdb:5T75|rcsb pdb:5TFX|rcsb pdb:5TH4|rcsb pdb:5THI|rcsb pdb:5THJ|rcsb pdb:5THN|rcsb pdb:5TI0|rcsb pdb:5TXY|rcsb pdb:5TY1|rcsb pdb:5TY8|rcsb pdb:5TY9|rcsb pdb:5TYA|rcsb pdb:5U0D|rcsb pdb:5U0E|rcsb pdb:5U0F|rcsb pdb:5U0G|rcsb pdb:5ULN|rcsb pdb:5UMC|rcsb pdb:5VGY|rcsb pdb:5W8B|rcsb pdb:5WEX|rcsb pdb:5WG7|rcsb pdb:5WGP|rcsb pdb:5WLR|rcsb pdb:5WLT|rcsb pdb:5WLU|rcsb pdb:5WLV|rcsb pdb:5Y2R|rcsb pdb:5Y2S|rcsb pdb:5YUI|rcsb pdb:5YUJ|rcsb pdb:5YUK|rcsb pdb:5ZXW|rcsb pdb:6B4D|rcsb pdb:6B59|rcsb pdb:6B5A|rcsb pdb:6BBS|rcsb pdb:6BC9|rcsb pdb:6BCC|rcsb pdb:6C7W|rcsb pdb:6C7X|rcsb pdb:6CA2|rcsb pdb:6CEH|rcsb pdb:6CJV|rcsb pdb:6D1L|rcsb pdb:6D1M|rcsb pdb:6E8P|rcsb pdb:6E8X|rcsb pdb:6E91|rcsb pdb:6E92|rcsb pdb:6EBE|rcsb pdb:6ECZ|rcsb pdb:6EDA|rcsb pdb:6EEA|rcsb pdb:6EEH|rcsb pdb:6EEO|rcsb pdb:6EQU|rcsb pdb:6FJI|rcsb pdb:6FJJ|rcsb pdb:6G3Q|rcsb pdb:6G6T|rcsb pdb:6GCY|rcsb pdb:6GDC|rcsb pdb:6GM9|rcsb pdb:6GOT|rcsb pdb:6KM4|rcsb pdb:6KM5|rcsb pdb:6GXB|rcsb pdb:6GXE|rcsb pdb:6H29|rcsb pdb:6H2Z|rcsb pdb:6H33|rcsb pdb:6H34|rcsb pdb:6H3Q|rcsb pdb:6H6S|rcsb pdb:6HD2|rcsb pdb:6HQX|rcsb pdb:6HR3|rcsb pdb:6HX5|rcsb pdb:6HXD|rcsb pdb:6HZX|rcsb pdb:6I0W|rcsb pdb:6I1U|rcsb pdb:6I2F|rcsb pdb:6I3E|rcsb pdb:6IC2|rcsb pdb:6KLZ|rcsb pdb:6KM0|rcsb pdb:6KM1|rcsb pdb:6KM2|rcsb pdb:6KM3|rcsb pdb:6KM6|rcsb pdb:6LUU|rcsb pdb:6LUV|rcsb pdb:6LUW|rcsb pdb:6LUX|rcsb pdb:6LUY|rcsb pdb:6LUZ|rcsb pdb:6LV1|rcsb pdb:6LV2|rcsb pdb:6LV3|rcsb pdb:6LV4|rcsb pdb:6LV5|rcsb pdb:6LV6|rcsb pdb:6LV7|rcsb pdb:6LV8|rcsb pdb:6LV9|rcsb pdb:6LVA|rcsb pdb:6MBV|rcsb pdb:6MBY|rcsb pdb:6NLV|rcsb pdb:6NM0|rcsb pdb:6ODZ|rcsb pdb:6OE0|rcsb pdb:6OE1|rcsb pdb:6OTI|rcsb pdb:6OTK|rcsb pdb:6OTM|rcsb pdb:6OTO|rcsb pdb:6OTP|rcsb pdb:6OTQ|rcsb pdb:6OUB|rcsb pdb:6OUD|rcsb pdb:6OUE|rcsb pdb:6OUF|rcsb pdb:6OUH|rcsb pdb:6OUI|rcsb pdb:6OUJ|rcsb pdb:6OUK|rcsb pdb:6OUM|rcsb pdb:6PDV|rcsb pdb:6PEA|rcsb pdb:6PGX|rcsb pdb:6Q3O|rcsb pdb:6Q9T|rcsb pdb:6QEB|rcsb pdb:6QL1|rcsb pdb:6QL2|rcsb pdb:6QL3|rcsb pdb:6R6F|rcsb pdb:6R6J|rcsb pdb:6RFH|rcsb pdb:6RG3|rcsb pdb:6RG4|rcsb pdb:6RG5|rcsb pdb:6RH4|rcsb pdb:6RHJ|rcsb pdb:6RHK|rcsb pdb:6RIG|rcsb pdb:6RIT|rcsb pdb:6RJJ|rcsb pdb:6RKN|rcsb pdb:6RL9|rcsb pdb:6RM1|rcsb pdb:6RMP|rcsb pdb:6RMX|rcsb pdb:6RMY|rcsb pdb:6RNP|rcsb pdb:6ROB|rcsb pdb:6ROE|rcsb pdb:6ROF|rcsb pdb:6RQI|rcsb pdb:6RRG|rcsb pdb:6RRI|rcsb pdb:6RS5|rcsb pdb:6RSZ|rcsb pdb:6RVF|rcsb pdb:6RVK|rcsb pdb:6RVL|rcsb pdb:6RW1|rcsb pdb:6RZX|rcsb pdb:6S03|rcsb pdb:6S9G|rcsb pdb:6S9Z|rcsb pdb:6SAC|rcsb pdb:6SAS|rcsb pdb:6SAY|rcsb pdb:6SB7|rcsb pdb:6SBH|rcsb pdb:6SBL|rcsb pdb:6SBM|rcsb pdb:6SD7|rcsb pdb:6SDH|rcsb pdb:6SDI|rcsb pdb:6SDJ|rcsb pdb:6SDL|rcsb pdb:6SDS|rcsb pdb:6SEY|rcsb pdb:6SFQ|rcsb pdb:6SFU|rcsb pdb:6SG0|rcsb pdb:6SG6|rcsb pdb:6SX9|rcsb pdb:6SYB|rcsb pdb:6SYS|rcsb pdb:6T4N|rcsb pdb:6T4O|rcsb pdb:6T4P|rcsb pdb:6T5C|rcsb pdb:6T7U|rcsb pdb:6T81|rcsb pdb:6T9Z|rcsb pdb:6U4Q|rcsb pdb:6U4T|rcsb pdb:6UFB|rcsb pdb:6UFC|rcsb pdb:6UFD|rcsb pdb:6UGN|rcsb pdb:6UGO|rcsb pdb:6UGP|rcsb pdb:6UGQ|rcsb pdb:6UGR|rcsb pdb:6UGZ|rcsb pdb:6UH0|rcsb pdb:6UX1|rcsb pdb:6UZU|rcsb pdb:6VJ3|rcsb pdb:6VKG|rcsb pdb:6WKA|rcsb pdb:6WQ4|rcsb pdb:6WQ5|rcsb pdb:6WQ7|rcsb pdb:6WQ8|rcsb pdb:6WQ9|rcsb pdb:6XVH|rcsb pdb:6XWZ|rcsb pdb:6XXT|rcsb pdb:6YH4|rcsb pdb:6YH5|rcsb pdb:6YH6|rcsb pdb:6YH7|rcsb pdb:6YH8|rcsb pdb:6YH9|rcsb pdb:6YHA|rcsb pdb:6YHB|rcsb pdb:6YHC|rcsb pdb:6YJ3|rcsb pdb:6YKC|rcsb pdb:6YKH|rcsb pdb:6YMA|rcsb pdb:6YMB|rcsb pdb:6YO2|rcsb pdb:6YO4|rcsb pdb:6YO7|rcsb pdb:6YOI|rcsb pdb:6YOK|rcsb pdb:6YOL|rcsb pdb:6YPW|rcsb pdb:6YQT|rcsb pdb:6YQU|rcsb pdb:6YRI|rcsb pdb:6YZJ|rcsb pdb:6YZK|rcsb pdb:6YZL|rcsb pdb:6YZM|rcsb pdb:6YZN|rcsb pdb:6YZO|rcsb pdb:6YZP|rcsb pdb:6YZQ|rcsb pdb:6YZR|rcsb pdb:6YZS|rcsb pdb:6YZT|rcsb pdb:6YZU|rcsb pdb:6YZV|rcsb pdb:6YZW|rcsb pdb:6YZX|rcsb pdb:6Z04|rcsb pdb:6ZR8|rcsb pdb:7A6V|rcsb pdb:7AEQ|rcsb pdb:7AES|rcsb pdb:7AGN|rcsb pdb:7ASJ|rcsb pdb:7BFA|rcsb pdb:7BG5|rcsb pdb:7BHH|rcsb pdb:7BI5|rcsb pdb:7CA2|rcsb pdb:7JNR|rcsb pdb:7JNV|rcsb pdb:7JNW|rcsb pdb:7JNX|rcsb pdb:7JNZ|rcsb pdb:7JO0|rcsb pdb:7JO1|rcsb pdb:7JO2|rcsb pdb:7JO3|rcsb pdb:7JOB|rcsb pdb:7JOC|rcsb pdb:7K6I|rcsb pdb:7K6J|rcsb pdb:7K6K|rcsb pdb:7K6L|rcsb pdb:7K6T|rcsb pdb:7K6U|rcsb pdb:7K6X|rcsb pdb:7K6Z|rcsb pdb:7M23|rcsb pdb:7M24|rcsb pdb:7M26|rcsb pdb:7MU3|rcsb pdb:7NH6|rcsb pdb:7NH8|rcsb pdb:7NTB|rcsb pdb:7NZR|rcsb pdb:7NZS|rcsb pdb:7NZT|rcsb pdb:7NZU|rcsb pdb:7NZW|rcsb pdb:7NZX|rcsb pdb:7OK8|rcsb pdb:7ONV|rcsb pdb:7ORP|rcsb pdb:7ORQ|rcsb pdb:7OYM|rcsb pdb:7OYN|rcsb pdb:7OYO|rcsb pdb:7OYP|rcsb pdb:7OYQ|rcsb pdb:7OYR|rcsb pdb:7Q0C|rcsb pdb:7Q0E|rcsb pdb:7QBH|rcsb pdb:7QGX|rcsb pdb:7QGY|rcsb pdb:7QGZ|rcsb pdb:7QNV|rcsb pdb:7QRK|rcsb pdb:7QSE|rcsb pdb:7RRE|rcsb pdb:7QSI|rcsb pdb:7QZX|rcsb pdb:7R1X|rcsb pdb:7RNY|rcsb pdb:7RNZ|rcsb pdb:7RRF|rcsb pdb:7SUW|rcsb pdb:7SUY|rcsb pdb:7SV1|rcsb pdb:7SV8|rcsb pdb:7U5W|rcsb pdb:7U5X|rcsb pdb:7Y2A|rcsb pdb:7Y2C|rcsb pdb:7Y2E|rcsb pdb:7Y2F|rcsb pdb:7Y2G|rcsb pdb:7Y2H|rcsb pdb:7Y2I|rcsb pdb:7Y2J|rcsb pdb:7Y2K|rcsb pdb:7Y2L|rcsb pdb:7Y2M|rcsb pdb:7Y2N|rcsb pdb:7Y2O|rcsb pdb:7Y2Q|rcsb pdb:7Y2R|rcsb pdb:7Y2S|rcsb pdb:7Y2T|rcsb pdb:7Y2U|rcsb pdb:7Y2V|rcsb pdb:7Y2W|rcsb pdb:7Y2X|rcsb pdb:7YWT|rcsb pdb:7ZL6|rcsb pdb:7ZWB|rcsb pdb:8AA6|rcsb pdb:8AAE|rcsb pdb:8B29|rcsb pdb:8BJX|rcsb pdb:8BOE|rcsb pdb:8BZZ|rcsb pdb:8C0Q|rcsb pdb:8C0R|rcsb pdb:8CA2|rcsb pdb:8CR0|rcsb pdb:8DJ9|rcsb pdb:8EM3|rcsb pdb:8EMU|rcsb pdb:8EXC|rcsb pdb:8EXG|rcsb pdb:8EYL|rcsb pdb:8FAL|rcsb pdb:8FAU|rcsb pdb:8FQX|rcsb pdb:8FQY|rcsb pdb:8FQZ|rcsb pdb:8FR1|rcsb pdb:8FR2|rcsb pdb:8FR4|rcsb pdb:8IGF|rcsb pdb:8J2O|rcsb pdb:8JEE|rcsb pdb:8OGD|rcsb pdb:8OGE|rcsb pdb:8OGF|rcsb pdb:8OKE|rcsb pdb:8OKG|rcsb pdb:8OKJ|rcsb pdb:8OKO|rcsb pdb:8OKP|rcsb pdb:8OKQ|rcsb pdb:8OKT|rcsb pdb:8OLA|rcsb pdb:8OLF|rcsb pdb:8OLI|rcsb pdb:8OLK|rcsb pdb:8OLM|rcsb pdb:8OMB|rcsb pdb:8OMH|rcsb pdb:8OMN|rcsb pdb:8OMP|rcsb pdb:8OO8|rcsb pdb:8OTP|rcsb pdb:8OUB|rcsb pdb:8P6U|rcsb pdb:8PHL|rcsb pdb:8PHM|rcsb pdb:8Q0C|rcsb pdb:8QF7|rcsb pdb:8QF9|rcsb pdb:8QFK|rcsb pdb:8QH8|rcsb pdb:8QHG|rcsb pdb:8QHJ|rcsb pdb:8QHO|rcsb pdb:8QKZ|rcsb pdb:8QQA|rcsb pdb:8QUF|rcsb pdb:8R1I|rcsb pdb:8RAR|rcsb pdb:8RBP|rcsb pdb:8RJ2|rcsb pdb:8SAF|rcsb pdb:8SAG|rcsb pdb:8SD1|rcsb pdb:8SD6|rcsb pdb:8SD7|rcsb pdb:8SD8|rcsb pdb:8SD9|rcsb pdb:8SF1|rcsb pdb:8WEP|rcsb pdb:8WER|rcsb pdb:8WES|rcsb pdb:8ZWV|rcsb pdb:9CA2|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-1475029|refseq:NP_000058.1|panther:PTHR18952(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:Er5rv/L2XS7uyrm/fPxFFsN+EsU9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:565EAC72E85D8D0E|rigid:SUsW/LV0bql9AbWP9EH6clpLE+g	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O15075	uniprotkb:Q83DF6	intact:EBI-2684263|uniprotkb:Q5VZZ1|uniprotkb:B7Z3E9|uniprotkb:Q5VZY8|uniprotkb:Q5VZZ0|ensembl:ENSP00000353846.3	intact:EBI-21285191	psi-mi:dclk1_human(display_long)|uniprotkb:DCAMKL1(gene name synonym)|uniprotkb:DCDC3A(gene name synonym)|uniprotkb:KIAA0369(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 1(gene name synonym)|uniprotkb:Doublecortin-like kinase 1(gene name synonym)|uniprotkb:Doublecortin domain-containing protein 3A(gene name synonym)|uniprotkb:DCLK1(gene name)|psi-mi:DCLK1(display_short)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285254|imex:IM-26899-107	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001182344.1|refseq:NP_001182345.1|refseq:NP_004725.1|refseq:NP_001317000.1|refseq:NP_001317001.1|ensembl:ENSG00000133083.15(gene)|ensembl:ENST00000360631.8(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007399""(nervous system development)|go:""GO:0007417""(central nervous system development)|go:""GO:0009615""(response to virus)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016197""(endosomal transport)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030900""(forebrain development)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048675""(axon extension)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036572|mint:O15075|rcsb pdb:1MFW|rcsb pdb:1MG4|rcsb pdb:1UF0|rcsb pdb:5JZJ|rcsb pdb:5JZN|rcsb pdb:6KYQ|rcsb pdb:6KYR|rcsb pdb:7F3G|rcsb pdb:7KX6|rcsb pdb:7KX8|rcsb pdb:7KXW|panther:PTHR24347(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:zCZrL4FeF69gU85zd6h/LE0nDI49606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:EA8E615A91F19275|rigid:p3agzkJALbXnOK8ScPRLQ/b2PGs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14766	uniprotkb:Q83DF6	intact:EBI-947693|uniprotkb:A1L3V1|uniprotkb:P22064|uniprotkb:Q53SD8|uniprotkb:Q53SF3|uniprotkb:Q53SG1|uniprotkb:Q59HF7|uniprotkb:Q8TD95|ensembl:ENSP00000386043.2	intact:EBI-21285191	psi-mi:ltbp1_human(display_long)|uniprotkb:LTBP1(gene name)|psi-mi:LTBP1(display_short)|uniprotkb:Transforming growth factor beta-1-binding protein 1(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285296|imex:IM-26899-447	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000049323.16(gene)|ensembl:ENST00000404816.7(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035583""(sequestering of TGFbeta in extracellular matrix)|go:""GO:0035592""(establishment of protein localization to extracellular region)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050436""(microfibril binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0141069""(receptor ligand inhibitor activity)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q14766|rcsb pdb:1KSQ|reactome:R-HSA-2129379|reactome:R-HSA-2173789|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000618.3|refseq:NP_001159736.1|refseq:NP_001159737.1|refseq:NP_001159738.1|refseq:NP_996826.2|refseq:XP_011531155.1|dip:DIP-50011N|efo:""Orphanet:90349""|panther:PTHR24034(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:OgHGfOcQWdQuLUT85Xg04lfggcs9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:9F251532986D10D1|rigid:ubPnm4xFNpISXSENZVf0wjpAaG0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99538	uniprotkb:Q83DF6	intact:EBI-2511794|ensembl:ENSP00000334052.4|ensembl:ENSP00000376911.2|uniprotkb:Q9BTY1|uniprotkb:O00123|intact:EBI-10963477|uniprotkb:Q86TV2|uniprotkb:Q86TV3	intact:EBI-21285191	psi-mi:lgmn_human(display_long)|uniprotkb:LGMN(gene name)|psi-mi:LGMN(display_short)|uniprotkb:PRSC1(gene name synonym)|uniprotkb:Asparaginyl endopeptidase(gene name synonym)|uniprotkb:Protease, cysteine 1(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285290|imex:IM-26899-109	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100600.15(gene)|ensembl:ENST00000334869.9(transcript)|ensembl:ENST00000393218.6(transcript)|go:""GO:0003014""(renal system process)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006624""(vacuolar protein processing)|go:""GO:0007613""(memory)|go:""GO:0008233""(peptidase activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008306""(associative learning)|go:""GO:0010447""(response to acidic pH)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0032801""(receptor catabolic process)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0036021""(endolysosome lumen)|go:""GO:0040015""(negative regulation of multicellular organism growth)|go:""GO:0042359""(vitamin D metabolic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0051604""(protein maturation)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|go:""GO:0097061""(dendritic spine organization)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097264""(self proteolysis)|go:""GO:1900273""(positive regulation of long-term synaptic potentiation)|go:""GO:1901185""(negative regulation of ERBB signaling pathway)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR043577|interpro:IPR046427|interpro:IPR048501|mint:Q99538|rcsb pdb:4AW9|rcsb pdb:4AWA|rcsb pdb:4AWB|rcsb pdb:4FGU|rcsb pdb:4N6N|rcsb pdb:4N6O|rcsb pdb:5LU8|rcsb pdb:5LU9|rcsb pdb:5LUA|rcsb pdb:5LUB|rcsb pdb:7FQH|rcsb pdb:7FQI|rcsb pdb:7FQJ|rcsb pdb:7FQK|rcsb pdb:7FQL|rcsb pdb:7O50|rcsb pdb:8AE4|rcsb pdb:8AE5|reactome:R-HSA-1679131|reactome:R-HSA-196791|reactome:R-HSA-2132295|refseq:NP_001008530.1|refseq:NP_005597.3|refseq:XP_005267919.1|refseq:XP_005267920.1|refseq:XP_016876952.1|refseq:XP_016876953.1|refseq:XP_016876954.1|refseq:XP_016876955.1|refseq:XP_016876956.1|panther:PTHR12000(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:W2jPq8/peH5iXt1wmbm8lFnkJwM9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:1B2E0123331DAAF0|rigid:4FANyorWpONCi+Bh5Djt5E9Us10	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O00505	uniprotkb:Q83DF6	intact:EBI-358297|intact:EBI-28976892|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|ensembl:ENSP00000261667.3|intact:EBI-742146|uniprotkb:Q8IYQ9|intact:EBI-21359997	intact:EBI-21285191	psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285284|imex:IM-26899-445	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR23316(orthology-group)|ensembl:ENSG00000102753.10(gene)|ensembl:ENST00000261667.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0042564""(NLS-dependent protein nuclear import complex)|go:""GO:0043657""(host cell)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0075732""(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276|refseq:NP_002258.2|dip:DIP-27586N|efo:""Orphanet:171612"""	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:3A47235348046E88|rigid:2z6fMftN89WjgDDEDeP7TNJeJaE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q92820	uniprotkb:Q83DF6	intact:EBI-3045534|ensembl:ENSP00000260118.6	intact:EBI-21285191	psi-mi:ggh_human(display_long)|uniprotkb:GGH(gene name)|psi-mi:GGH(display_short)|uniprotkb:Conjugase(gene name synonym)|uniprotkb:GH(gene name synonym)|uniprotkb:Gamma-Glu-X carboxypeptidase(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285272|imex:IM-26899-203	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:1L9X|ensembl:ENSG00000137563.13(gene)|ensembl:ENST00000260118.7(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005773""(vacuole)|go:""GO:0008238""(exopeptidase activity)|go:""GO:0008242""(omega peptidase activity)|go:""GO:0034722""(gamma-glutamyl-peptidase activity)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042470""(melanosome)|go:""GO:0046900""(tetrahydrofolylpolyglutamate metabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904724""(tertiary granule lumen)|interpro:IPR011697(Peptidase C26)|interpro:IPR015527(Peptidase C26, gamma-glutamyl hydrolase)|interpro:IPR029062|mint:Q92820|reactome:R-HSA-6798695|refseq:NP_003869.1|panther:PTHR11315(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:QjPbv+fLXWnf6gmW2PsXVuyatR49606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:7C868714C8D45BA4|rigid:4BxTSWaFx/U43BqJOC771VxcVpo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O14979	uniprotkb:Q83DF6	intact:EBI-299727|uniprotkb:Q6SPF2|uniprotkb:Q7KZ74|uniprotkb:Q7KZ75|uniprotkb:Q96IM0|uniprotkb:Q96S43|ensembl:ENSP00000295470.5|ensembl:ENSP00000422040.1|ensembl:ENSP00000483254.1	intact:EBI-21285191	psi-mi:hnrdl_human(display_long)|uniprotkb:HNRNPDL(gene name)|psi-mi:HNRNPDL(display_short)|uniprotkb:AU-rich element RNA-binding factor(gene name synonym)|uniprotkb:HNRPDL(gene name synonym)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:JKTBP(gene name synonym)|uniprotkb:Protein laAUF1(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285278|imex:IM-26899-549	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000152795.18(gene)|ensembl:ENST00000295470.10(transcript)|ensembl:ENST00000502762.4(transcript)|ensembl:ENST00000621267.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0010468""(regulation of gene expression)|go:""GO:0034046""(""poly(G) binding"")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034847|interpro:IPR035979|mint:O14979|rcsb pdb:7ZIR|reactome:R-HSA-8950505|refseq:NP_001193929.1|refseq:NP_112740.1|efo:""Orphanet:55596""|panther:PTHR48033(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:oOnEEar8AtKO5G6ldehucaRr4kM9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:BB5AA408517A4057|rigid:PiMvt6LpSdjN1jkOLNp3EHLUcRE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P30273	uniprotkb:Q83DF6	intact:EBI-515289|uniprotkb:Q5VTW4|ensembl:ENSP00000289902.1	intact:EBI-21285191	psi-mi:fcerg_human(display_long)|uniprotkb:IgE Fc receptor subunit gamma(gene name synonym)|uniprotkb:Fc-epsilon RI-gamma(gene name synonym)|uniprotkb:FCER1G(gene name)|psi-mi:FCER1G(display_short)|uniprotkb:Fc receptor gamma-chain(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285266|imex:IM-26899-335	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004097.1|ensembl:ENSG00000158869.11(gene)|ensembl:ENST00000289902.2(transcript)|go:""GO:0002283""(neutrophil activation involved in immune response)|go:""GO:0002292""(T cell differentiation involved in immune response)|go:""GO:0002431""(Fc receptor mediated stimulatory signaling pathway)|go:""GO:0005886""(plasma membrane)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010543""(regulation of platelet activation)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019767""(IgE receptor activity)|go:""GO:0019863""(IgE binding)|go:""GO:0019864""(IgG binding)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0031623""(receptor internalization)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032998""(Fc-epsilon receptor I complex)|go:""GO:0033001""(Fc-gamma receptor III complex)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0038156""(interleukin-3-mediated signaling pathway)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045087""(innate immune response)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR042340|mint:P30273|rcsb pdb:7Q5T|reactome:R-HSA-114604|reactome:R-HSA-202733|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5621480|reactome:R-HSA-6798695|reactome:R-HSA-75892|dip:DIP-29514N|panther:PTHR16803(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:sYW44kyg+jmeUmR9vWSSPdyq4N49606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:BE58A1EC5B520BFC|rigid:r/2hWduE2qCHACX66ES5kQb4+y0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8N0U8	uniprotkb:Q83DF6	intact:EBI-11337915|uniprotkb:E7ETM5|uniprotkb:Q6AHW9|uniprotkb:B4E222|uniprotkb:Q6TEK6|ensembl:ENSP00000353998.2|ensembl:ENSP00000497394.1	intact:EBI-21285191	psi-mi:vkorl_human(display_long)|uniprotkb:VKORC1L1(gene name)|psi-mi:VKORC1L1(display_short)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285378|imex:IM-26899-561	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001271271.1|refseq:NP_775788.2|ensembl:ENSG00000196715.7(gene)|ensembl:ENST00000360768.5(transcript)|ensembl:ENST00000648179.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0017187""(peptidyl-glutamic acid carboxylation)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0042373""(vitamin K metabolic process)|go:""GO:0047057""(""vitamin-K-epoxide reductase (warfarin-sensitive) activity"")|go:""GO:0048038""(quinone binding)|interpro:IPR012932(Vitamin K epoxide reductase)|interpro:IPR038354|interpro:IPR042406|mint:Q8N0U8|reactome:R-HSA-6806664|panther:PTHR14519(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:0gdoyZTMoqEjTsPOfeUNSlH4M7k9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:A4067805F76C72FE|rigid:PdfEnjmcGa+uuKy6mjRRG6RbZbw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8IYB4	uniprotkb:Q83DF6	intact:EBI-15749355|intact:EBI-28986271|uniprotkb:B7Z2A5|uniprotkb:B7Z305|uniprotkb:B7Z318|uniprotkb:B7Z5Z5|uniprotkb:B7Z8P2|uniprotkb:E7EUV8|uniprotkb:E7EUZ0|uniprotkb:E9PEC1|uniprotkb:E9PH97|uniprotkb:Q9NQD1|uniprotkb:Q9P2U3|uniprotkb:Q9P2U4|ensembl:ENSP00000419975.1	intact:EBI-21285191	psi-mi:pex5r_human(display_long)|uniprotkb:PEX5L(gene name)|psi-mi:PEX5L(display_short)|uniprotkb:PEX5R(gene name synonym)|uniprotkb:PXR2(gene name synonym)|uniprotkb:PEX2-related protein(gene name synonym)|uniprotkb:PEX5-like protein(gene name synonym)|uniprotkb:Peroxin-5-related protein(gene name synonym)|uniprotkb:Peroxisome biogenesis factor 5-like(gene name synonym)|uniprotkb:Tetratricopeptide repeat-containing Rab8b-interacting protein(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285320|imex:IM-26899-221	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001243679.1|refseq:NP_001243680.1|refseq:NP_001243681.1|refseq:NP_001243682.1|refseq:NP_001243683.1|refseq:NP_001243684.1|refseq:NP_001243685.1|refseq:NP_057643.1|refseq:XP_011511189.1|refseq:XP_011511193.1|refseq:XP_011511194.1|refseq:XP_016862095.1|refseq:XP_016862096.1|refseq:XP_016862097.1|refseq:XP_016862098.1|refseq:XP_016862099.1|refseq:XP_016862100.1|dip:DIP-58547N|panther:PTHR10130(orthology-group)|ensembl:ENSG00000114757.19(gene)|ensembl:ENST00000467460.6(transcript)|go:""GO:0000268""(peroxisome targeting sequence binding)|go:""GO:0005052""(peroxisome matrix targeting signal-1 binding)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0016560""(protein import into peroxisome matrix, docking)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043235""(receptor complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|mint:Q8IYB4"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ToCqEYoApcFXqlRyDgfd/tchKRM9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:C7E2248AB3C3869F|rigid:xV1OgKjvlZl+Mb4RgPTKLoRNpyw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q1EHB4	uniprotkb:Q83DF6	intact:EBI-21285338|ensembl:ENSP00000379326.3|uniprotkb:Q86UC7	intact:EBI-21285191	psi-mi:sc5ac_human(display_long)|uniprotkb:SLC5A12(gene name)|psi-mi:SLC5A12(display_short)|uniprotkb:SMCT2(gene name synonym)|uniprotkb:Electroneutral sodium monocarboxylate cotransporter(gene name synonym)|uniprotkb:Low-affinity sodium-lactate cotransporter(gene name synonym)|uniprotkb:Solute carrier family 5 member 12(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285360|imex:IM-26899-553	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000148942.15(gene)|ensembl:ENST00000396005.8(transcript)|go:""GO:0005343""(""organic acid:sodium symporter activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006814""(sodium ion transport)|go:""GO:0015129""(lactate transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|go:""GO:0015718""(monocarboxylic acid transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140161""(""monocarboxylate:sodium symporter activity"")|interpro:IPR001734(Na+/solute symporter)|interpro:IPR038377|interpro:IPR042700|interpro:IPR051163|mint:Q1EHB4|reactome:R-HSA-427601|refseq:NP_848593.2|panther:PTHR42985(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:yIZjC3TzY1kdEvq2qDj/CKb2jVc9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:06DF1B4A085B3CC7|rigid:jU5GF9N2FxEsIsbk2i+zDc6YCeU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UKK3	uniprotkb:Q83DF6	intact:EBI-2623021|uniprotkb:Q5QNZ9|uniprotkb:O75903|uniprotkb:Q14682|uniprotkb:Q9H1M6|ensembl:ENSP00000371419.3	intact:EBI-21285191	"psi-mi:parp4_human(display_long)|uniprotkb:ADPRTL1(gene name synonym)|uniprotkb:KIAA0177(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:193 kDa vault protein(gene name synonym)|uniprotkb:PARP-related/IalphaI-related H5/proline-rich(gene name synonym)|uniprotkb:""Vault poly(ADP-ribose) polymerase""(gene name synonym)|uniprotkb:PARP4(gene name)|psi-mi:PARP4(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 4(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 4(gene name synonym)"	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285314|imex:IM-26899-449	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011533234.1|refseq:NP_006428.2|ensembl:ENSG00000102699.6(gene)|ensembl:ENST00000381989.4(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005876""(spindle microtubule)|go:""GO:0006281""(DNA repair)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016020""(membrane)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0036211""(protein modification process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140806""(NAD+-protein-aspartate ADP-ribosyltransferase activity)|go:""GO:0140822""(NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity)|go:""GO:0140844""(NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity)|go:""GO:0140867""(NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity)|go:""GO:1990404""(NAD+-protein mono-ADP-ribosyltransferase activity)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001357(BRCT)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004102(""Poly(ADP-ribose) polymerase, regulatory region"")|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR031273|interpro:IPR036420|interpro:IPR036465|interpro:IPR036616|mint:Q9UKK3|rcsb pdb:8SWY|rcsb pdb:8SWZ|rcsb pdb:8SX1|rcsb pdb:8SX2|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|panther:PTHR46530(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:d1n+oei4ZSmqUnvJzMe6RLq2XOc9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:233DF3F8F499EC47|rigid:55uEzh09onA0Q2aNoJTWMYBOdYg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q93045	uniprotkb:Q83DF6	intact:EBI-714194|uniprotkb:O14952|uniprotkb:Q6PK68|uniprotkb:A8K9M2|uniprotkb:G3V110|ensembl:ENSP00000220876.7	intact:EBI-21285191	psi-mi:stmn2_human(display_long)|uniprotkb:Superior cervical ganglion-10 protein(gene name synonym)|uniprotkb:STMN2(gene name)|psi-mi:STMN2(display_short)|uniprotkb:SCG10(gene name synonym)|uniprotkb:SCGN10(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285366|imex:IM-26899-9	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_008960.2|refseq:NP_001186143.1|ensembl:ENSG00000104435.14(gene)|ensembl:ENST00000220876.12(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007019""(microtubule depolymerization)|go:""GO:0007026""(negative regulation of microtubule depolymerization)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0015631""(tubulin binding)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030426""(growth cone)|go:""GO:0031110""(regulation of microtubule polymerization or depolymerization)|go:""GO:0031115""(negative regulation of microtubule polymerization)|go:""GO:0031117""(positive regulation of microtubule depolymerization)|go:""GO:0031175""(neuron projection development)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|interpro:IPR000956(Stathmin)|interpro:IPR030514|interpro:IPR036002|mint:Q93045|reactome:R-HSA-9696273|panther:PTHR10104(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:tM3wU+n2JiO1Cp4YeaAOYgBCDDA9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:0C462DF4089AA4DD|rigid:64c2KOSD5lONZ083Sf6rF4g0k80	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NX40	uniprotkb:Q83DF6	intact:EBI-2683029|uniprotkb:C9K030|uniprotkb:Q9BZE8|uniprotkb:G8JLN7|ensembl:ENSP00000264312.7|ensembl:ENSP00000370882.3|ensembl:ENSP00000423002.1|ensembl:ENSP00000423909.2	intact:EBI-21285191	psi-mi:ocad1_human(display_long)|uniprotkb:OCIA(gene name synonym)|uniprotkb:Ovarian carcinoma immunoreactive antigen(gene name synonym)|uniprotkb:OCIAD1(gene name)|psi-mi:OCIAD1(display_short)|uniprotkb:ASRIJ(gene name synonym)|uniprotkb:Ovarian cancer immunoreactive antigen domain containing 1(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285302|imex:IM-26899-337	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001073309.1|refseq:NP_001073311.2|refseq:NP_001073308.1|refseq:NP_001073310.1|refseq:NP_060300.1|refseq:XP_016863818.1|ensembl:ENSG00000109180.15(gene)|ensembl:ENST00000264312.12(transcript)|ensembl:ENST00000381473.7(transcript)|ensembl:ENST00000508293.5(transcript)|ensembl:ENST00000513391.2(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006897""(endocytosis)|go:""GO:0016020""(membrane)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|go:""GO:2000736""(regulation of stem cell differentiation)|interpro:IPR009764(Ovarian carcinoma immunoreactive antigen)|interpro:IPR040187|mint:Q9NX40|panther:PTHR13336(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:e3Ojv8LBlgj056bssUZjEC+MB+Q9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:DB64DEEFB5440FBD|rigid:4InJ3OPdicngjsNpg7ezCF0MgSA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00439	uniprotkb:Q83DF6	intact:EBI-2861444|uniprotkb:Q16717|uniprotkb:Q8TC14|ensembl:ENSP00000448059.1	intact:EBI-21285191	psi-mi:ph4h_human(display_long)|uniprotkb:PAH(gene name)|psi-mi:PAH(display_short)|uniprotkb:Phe-4-monooxygenase(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285308|imex:IM-26899-339	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-58927N|ensembl:ENSG00000171759.10(gene)|ensembl:ENST00000553106.6(transcript)|go:""GO:0004505""(phenylalanine 4-monooxygenase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006559""(L-phenylalanine catabolic process)|go:""GO:0006571""(tyrosine biosynthetic process)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0042423""(catecholamine biosynthetic process)|interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR005961(Phenylalanine-4-hydroxylase, tetrameric form)|interpro:IPR018301|interpro:IPR019773|interpro:IPR019774|interpro:IPR036329|interpro:IPR036951|interpro:IPR041912|interpro:IPR045865|mint:P00439|rcsb pdb:1DMW|rcsb pdb:1J8T|rcsb pdb:1J8U|rcsb pdb:1KW0|rcsb pdb:1LRM|rcsb pdb:1MMK|rcsb pdb:1MMT|rcsb pdb:1PAH|rcsb pdb:1TDW|rcsb pdb:1TG2|rcsb pdb:2PAH|rcsb pdb:3PAH|rcsb pdb:4ANP|rcsb pdb:4PAH|rcsb pdb:5FII|rcsb pdb:5PAH|rcsb pdb:6HPO|rcsb pdb:6HYC|rcsb pdb:6N1K|rcsb pdb:6PAH|reactome:R-HSA-2160456|reactome:R-HSA-8964208|refseq:NP_000268.1|efo:""Orphanet:2209""|efo:""Orphanet:293284""|efo:""Orphanet:79253""|efo:""Orphanet:79254""|efo:""Orphanet:79651""|panther:PTHR11473(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:byO1PdD6RTWtUZOt5A9/N/Gl4Do9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:78F6EB55CA799B1B|rigid:Dc5LJB5XIrKoCFt7aRoRAF4NFi4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O15173	uniprotkb:Q83DF6	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425.4|ensembl:ENSP00000429301.2	intact:EBI-21285191	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285326|imex:IM-26899-451	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006311.2|ensembl:ENSG00000164040.18(gene)|ensembl:ENST00000296425.10(transcript)|ensembl:ENST00000520121.6(transcript)|go:""GO:0003707""(nuclear steroid receptor activity)|go:""GO:0005496""(steroid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0012505""(endomembrane system)|go:""GO:0015232""(heme transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0060612""(adipose tissue development)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|interpro:IPR050577|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9707616|panther:PTHR10281(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:9265B14C907B4422|rigid:7b4z6nCmq84hE/+ZrGPxKKQl9mM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P48382	uniprotkb:Q83DF6	intact:EBI-923266|uniprotkb:Q5VWC3|uniprotkb:D3DV19|ensembl:ENSP00000290524.4|ensembl:ENSP00000357864.2|ensembl:ENSP00000389130.2|uniprotkb:B7Z848|uniprotkb:E9PFU4	intact:EBI-21285191	psi-mi:rfx5_human(display_long)|uniprotkb:RFX5(gene name)|psi-mi:RFX5(display_short)|uniprotkb:Regulatory factor X 5(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285332|imex:IM-26899-551	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143390.18(gene)|ensembl:ENST00000290524.8(transcript)|ensembl:ENST00000368870.6(transcript)|ensembl:ENST00000452671.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045348""(positive regulation of MHC class II biosynthetic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR029298|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|mint:P48382|rcsb pdb:2KW3|rcsb pdb:3V30|refseq:NP_000440.1|refseq:NP_001020774.1|refseq:XP_005245462.1|refseq:XP_005245463.1|refseq:XP_011508149.1|refseq:XP_011508150.1|refseq:XP_011508151.1|refseq:XP_011508152.1|efo:""Orphanet:572""|panther:PTHR12619(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:kElLakR+ct4K8Mw6q91im3K8Zh89606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:7E8DCCA1D63DACEC|rigid:lUYBOwaqdRdQK+vgnz4NRX25mTo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8IXX5	uniprotkb:Q83DF6	intact:EBI-2841953|uniprotkb:A8K5W1|uniprotkb:Q6NW15|uniprotkb:Q96E06|ensembl:ENSP00000356211.3	intact:EBI-21285191	psi-mi:t183a_human(display_long)|uniprotkb:TMEM183A(gene name)|psi-mi:TMEM183A(display_short)|uniprotkb:C1orf37(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285372|imex:IM-26899-741	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_612400.3|ensembl:ENSG00000163444.12(gene)|ensembl:ENST00000367242.4(transcript)|go:""GO:0016020""(membrane)|go:""GO:0019005""(SCF ubiquitin ligase complex)|go:""GO:0031647""(regulation of protein stability)|interpro:IPR026509|interpro:IPR036047|mint:Q8IXX5|panther:PTHR20988(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:XNJR0b9RbNBEXSE9ohP+TfVtxzM9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:7511C16331067210|rigid:CcEnP/Z5j291L7IA0z3ExJlNoQU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8N5P1	uniprotkb:Q83DF6	intact:EBI-5280267|uniprotkb:Q9BZ75|ensembl:ENSP00000386488.1	intact:EBI-21285191	psi-mi:zc3h8_human(display_long)|uniprotkb:ZC3H8(gene name)|psi-mi:ZC3H8(display_short)|uniprotkb:ZC3HDC8(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285396|imex:IM-26899-223	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115883.2|ensembl:ENSG00000144161.14(gene)|ensembl:ENST00000409573.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0001162""(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0008023""(transcription elongation factor complex)|go:""GO:0015030""(Cajal body)|go:""GO:0016604""(nuclear body)|go:""GO:0033085""(negative regulation of T cell differentiation in thymus)|go:""GO:0035363""(histone locus body)|go:""GO:0042795""(snRNA transcription by RNA polymerase II)|go:""GO:0042796""(snRNA transcription by RNA polymerase III)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045945""(positive regulation of transcription by RNA polymerase III)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046872""(metal ion binding)|go:""GO:0070245""(positive regulation of thymocyte apoptotic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR045124|interpro:IPR054361|mint:Q8N5P1|reactome:R-HSA-6807505|panther:PTHR13119(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ltW8I583M/LV8XKPzLRvojXc+AA9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:62CD3681841F976C|rigid:knQPKVk2a+q+j5Q+5mQSv5lRqzg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8WU90	uniprotkb:Q83DF6	intact:EBI-1042636|uniprotkb:Q5QTQ4|uniprotkb:Q8WZ06|uniprotkb:Q9NUZ3|uniprotkb:Q9P079|uniprotkb:Q9NZ37|uniprotkb:B4DMW2|uniprotkb:D3DPG7|ensembl:ENSP00000338788.6	intact:EBI-21285191	psi-mi:zc3hf_human(display_long)|uniprotkb:ZC3H15(gene name)|psi-mi:ZC3H15(display_short)|uniprotkb:DFRP1(gene name synonym)|uniprotkb:LEREPO4(gene name synonym)|uniprotkb:DRG family-regulatory protein 1(gene name synonym)|uniprotkb:Likely ortholog of mouse immediate early response erythropoietin 4(gene name synonym)|uniprotkb:HSPC303(orf name)|uniprotkb:HT010(orf name)|uniprotkb:MSTP012(orf name)|uniprotkb:PP730(orf name)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285390|imex:IM-26899-11	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060941.2|ensembl:ENSG00000065548.19(gene)|ensembl:ENST00000337859.11(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR032378|interpro:IPR036855|mint:Q8WU90|reactome:R-HSA-9629569|panther:PTHR12681(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:MrcssHMHDoQKqsIXdhfMWOnHlBY9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:5DC45FC6981CDF44|rigid:tMxZdX80/zCXH89j4y4pBhxo2gs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75132	uniprotkb:Q83DF6	intact:EBI-2860059|uniprotkb:B2RZH1|uniprotkb:Q9UGG8|uniprotkb:Q1ECU0|ensembl:ENSP00000216268.4	intact:EBI-21285191	psi-mi:zbed4_human(display_long)|uniprotkb:ZBED4(gene name)|psi-mi:ZBED4(display_short)|uniprotkb:KIAA0637(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285384|imex:IM-26899-645	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055653.2|ensembl:ENSG00000100426.8(gene)|ensembl:ENST00000216268.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0042802""(identical protein binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046983""(protein dimerization activity)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|interpro:IPR052035|mint:O75132|panther:PTHR46481(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:T1pqiOcpLeOA25QudngK1xk+xaA9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:605140EDE73FE4A1|rigid:+p+H+wxZpfDuSlGf8rxwuQP18Ss	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H6R6	uniprotkb:Q83DF6	intact:EBI-725179|uniprotkb:Q53G45|uniprotkb:Q96IV7|uniprotkb:Q9H605|uniprotkb:D3DRB6|ensembl:ENSP00000358413.3|ensembl:ENSP00000507009.1|ensembl:ENSP00000507661.1	intact:EBI-21285191	psi-mi:zdhc6_human(display_long)|uniprotkb:Zinc finger DHHC domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger protein 376(gene name synonym)|uniprotkb:Transmembrane protein H4(gene name synonym)|uniprotkb:ZDHHC6(gene name)|psi-mi:ZDHHC6(display_short)|uniprotkb:ZNF376(gene name synonym)|uniprotkb:Stearoyltransferase ZDHHC6(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285402|imex:IM-26899-225	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_071939.1|refseq:XP_005270108.1|refseq:XP_006718011.1|ensembl:ENSG00000023041.12(gene)|ensembl:ENST00000369405.7(transcript)|ensembl:ENST00000683895.1(transcript)|ensembl:ENST00000684507.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0010636""(positive regulation of mitochondrial fusion)|go:""GO:0016409""(palmitoyltransferase activity)|go:""GO:0018345""(protein palmitoylation)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0140438""(protein stearoylation)|go:""GO:0140439""(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR039859|mint:Q9H6R6|refseq:NP_001290063.1|refseq:XP_016872050.1|refseq:XP_016872051.1|refseq:XP_016872052.1|panther:PTHR22883(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:GLUdVccZzQNxx/i8l0yMS/p6GXo9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:F23C712D428E4C62|rigid:zhv3Cf1fIoRGvkk4ADu7KV/29vw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NR11	uniprotkb:Q83DF6	intact:EBI-3916142|uniprotkb:Q9P0J4|uniprotkb:Q9BZD8|uniprotkb:Q658J3	intact:EBI-21285191	psi-mi:zn302_human(display_long)|uniprotkb:ZNF302(gene name)|psi-mi:ZNF302(display_short)|uniprotkb:ZNF135L(gene name synonym)|uniprotkb:ZNF140L(gene name synonym)|uniprotkb:ZNF327(gene name synonym)|uniprotkb:Zinc finger protein 135-like(gene name synonym)|uniprotkb:Zinc finger protein 140-like(gene name synonym)|uniprotkb:Zinc finger protein 327(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285408|imex:IM-26899-743	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR036051|interpro:IPR036236|refseq:NP_001012320.1|refseq:NP_060913.2|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001276116.1|refseq:NP_001276117.1|refseq:NP_001276118.1|refseq:NP_001276110.1|refseq:NP_001276111.1|refseq:NP_001276119.1|refseq:NP_001276112.1|refseq:NP_001276113.1|refseq:NP_001276120.1|refseq:NP_001276114.1|refseq:NP_001276115.1|refseq:NP_001276121.1|refseq:NP_061145.2|mint:Q9NR11|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|reactome:R-HSA-212436|panther:PTHR24377(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:FihdHXyOLfG5HUdPhyThDDsJHkA9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:67C3F5A84E5E94CE|rigid:mdO1rgTGCnO19QRRZxdlwyiNfqc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q83DE4	uniprotkb:Q13137	intact:EBI-21285423	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5|ensembl:ENSP00000258947.3	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285435|imex:IM-26899-453	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	"refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|refseq:NP_001248324.1|ensembl:ENSG00000136436.16(gene)|ensembl:ENST00000258947.8(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005776""(autophagosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016032""(viral process)|go:""GO:0016605""(PML body)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034341""(response to type II interferon)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0098792""(xenophagy)|go:""GO:1901098""(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|interpro:IPR051002|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|rcsb pdb:7EAA|dip:DIP-57534N|panther:PTHR31915(orthology-group)"	-	-	crc64:609B121DA1A9DCB8	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/10	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:D82C928DB3ABCB5D|rigid:0Wk3ugIC7O1MWcWd1gq46Y8wqGo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8NAN2	uniprotkb:Q83DE4	intact:EBI-13943438|ensembl:ENSP00000518551.1|uniprotkb:Q6MZG0	intact:EBI-21285423	psi-mi:miga1_human(display_long)|uniprotkb:MIGA1(gene name)|psi-mi:MIGA1(display_short)|uniprotkb:FAM73A(gene name synonym)|uniprotkb:Protein FAM73A(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285447|imex:IM-26899-341	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000180488.17(gene)|ensembl:ENST00000710932.1(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0008053""(mitochondrial fusion)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046982""(protein heterodimerization activity)|interpro:IPR019392|mint:Q8NAN2|reactome:R-HSA-1483166|refseq:NP_001257313.1|refseq:NP_940951.1|panther:PTHR21508(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ZIDtgENE8en73tFnADIVIal9wcg9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:7D1E546826FD2C6A|rigid:JL31FQj0DDusidun8UNouSNBd0o	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75123	uniprotkb:Q83DF6	intact:EBI-18560922|ensembl:ENSP00000445979.1|ensembl:ENSP00000487869.1|uniprotkb:A4FU80|uniprotkb:B4DGP3|uniprotkb:E7ENV5	intact:EBI-21285191	psi-mi:zn623_human(display_long)|uniprotkb:ZNF623(gene name)|psi-mi:ZNF623(display_short)|uniprotkb:KIAA0628(gene name synonym)	psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285417|imex:IM-26899-745	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000183309.12(gene)|ensembl:ENSG00000276340.4(gene)|ensembl:ENST00000501748.3(transcript)|ensembl:ENST00000633071.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O75123|refseq:NP_001075949.1|refseq:NP_001248772.1|refseq:NP_055604.3|refseq:XP_006716771.1|panther:PTHR24377(orthology-group)"	mint:Q83DF6|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ZPDs42UpkZdzLtqeMEZie5uUhdA9606	rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377	intact-crc:721129A3B2760FB6|rigid:h4LwyiGdqoFQi0GlNn6buSQ8ZDo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y3M2	uniprotkb:Q83DE4	intact:EBI-947308|uniprotkb:Q66GT6|uniprotkb:Q9UIK9|uniprotkb:B2R4S2|ensembl:ENSP00000216029.3|ensembl:ENSP00000380026.2|ensembl:ENSP00000412260.2|ensembl:ENSP00000413934.2	intact:EBI-21285423	psi-mi:cby1_human(display_long)|uniprotkb:CBY1(gene name)|psi-mi:CBY1(display_short)|uniprotkb:C22orf2(gene name synonym)|uniprotkb:CBY(gene name synonym)|uniprotkb:HRIHFB2025(orf name)|uniprotkb:ARB1(gene name synonym)|uniprotkb:PGEA1(gene name synonym)|uniprotkb:PKD2 interactor, Golgi and endoplasmic reticulum-associated 1(gene name synonym)|uniprotkb:PIGEA-14(gene name synonym)|uniprotkb:Cytosolic leucine-rich protein(gene name synonym)|uniprotkb:ARPP-binding protein(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285441|imex:IM-26899-563	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100211.12(gene)|ensembl:ENST00000216029.8(transcript)|ensembl:ENST00000396811.6(transcript)|ensembl:ENST00000411557.6(transcript)|ensembl:ENST00000416285.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008104""(protein localization)|go:""GO:0016607""(nuclear speck)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0033504""(floor plate development)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060271""(cilium assembly)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|interpro:IPR028118|mint:Q9Y3M2|rcsb pdb:4WRQ|reactome:R-HSA-3769402|refseq:NP_001002880.2|refseq:NP_056188.1|dip:DIP-29651N|efo:""Orphanet:475""|panther:PTHR21533(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:RqvyVBe3nAEf0bYnToiVsM5hLhc9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:D4FDA078BAC58FB0|rigid:vFnPTlXRna1ZE9gghKtkET9gbDk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15389	uniprotkb:Q83DE4	intact:EBI-2922365|uniprotkb:Q5HYA0|ensembl:ENSP00000428340.1	intact:EBI-21285423	psi-mi:angp1_human(display_long)|uniprotkb:ANGPT1(gene name)|psi-mi:ANGPT1(display_short)|uniprotkb:KIAA0003(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285429|imex:IM-26899-13	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000154188.10(gene)|ensembl:ENST00000517746.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0002719""(negative regulation of cytokine production involved in immune response)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007171""(activation of transmembrane receptor protein tyrosine kinase activity)|go:""GO:0007596""(blood coagulation)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014842""(regulation of skeletal muscle satellite cell proliferation)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030210""(heparin proteoglycan biosynthetic process)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0045121""(membrane raft)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0048014""(Tie signaling pathway)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050820""(positive regulation of coagulation)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0072012""(glomerulus vasculature development)|go:""GO:1905605""(positive regulation of blood-brain barrier permeability)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|go:""GO:2000446""(regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037579|mint:Q15389|rcsb pdb:4EPU|rcsb pdb:4JYO|rcsb pdb:4K0V|reactome:R-HSA-210993|reactome:R-HSA-5673001|refseq:NP_001137.2|refseq:NP_001186788.1|refseq:NP_001300980.1|efo:""Orphanet:599418""|panther:PTHR19143(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:UQX0FGhzdmPbYOvuvmXxBdkEgjk9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:7F11850570932315|rigid:ynj5TnB5OoYuzNGp5ngOZZw0310	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96SU4	uniprotkb:Q83DE4	intact:EBI-2511368|ensembl:ENSP00000407168.1|uniprotkb:Q6IA67|uniprotkb:Q9H9X2|uniprotkb:Q96SK4|uniprotkb:B1AKJ8|uniprotkb:Q5TFC0|uniprotkb:Q8NB17|uniprotkb:Q8TAS8|uniprotkb:D3DQ31|uniprotkb:B3KPQ4|uniprotkb:Q86YQ3	intact:EBI-21285423	psi-mi:osbl9_human(display_long)|uniprotkb:OSBPL9(gene name)|psi-mi:OSBPL9(display_short)|uniprotkb:ORP9(gene name synonym)|uniprotkb:OSBP4(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285477|imex:IM-26899-747	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000117859.19(gene)|ensembl:ENST00000428468.6(transcript)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032934""(sterol binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0120015""(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q96SU4|reactome:R-HSA-192105|refseq:XP_011538905.1|refseq:XP_011538906.1|refseq:NP_078862.4|refseq:NP_683702.1|refseq:NP_683703.1|refseq:NP_683705.1|refseq:NP_683706.3|refseq:NP_683704.2|refseq:NP_683707.3|refseq:XP_006710386.1|refseq:XP_006710387.1|refseq:XP_006710388.1|refseq:XP_006710389.1|refseq:NP_001317509.1|refseq:XP_016855708.1|refseq:XP_016855709.1|refseq:XP_016855710.1|panther:PTHR10972(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:2XLQ0JD4BEKGoyiwd/63YTmyVlE9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:E48BFA82D7858E7F|rigid:BSEP4+hnDpDexj1yX/jPJ6BXK5M	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q03112	uniprotkb:Q83DE4	intact:EBI-1384862|uniprotkb:Q16122|uniprotkb:Q99917|uniprotkb:C9JAK0|uniprotkb:Q5HYI1|uniprotkb:Q6MZS6|uniprotkb:Q8NEI5|uniprotkb:A1L4F3|uniprotkb:A8KA00|uniprotkb:B7Z8W7|uniprotkb:B7ZLQ3|uniprotkb:B7ZLQ4|uniprotkb:D3DNP7|ensembl:ENSP00000417899.1|intact:EBI-8475192|intact:MINT-8417693|uniprotkb:E7EQ57|uniprotkb:Q13465|uniprotkb:Q13466|uniprotkb:Q6FH90	intact:EBI-21285423	psi-mi:mecom_human(display_long)|uniprotkb:MECOM(gene name)|psi-mi:MECOM(display_short)|uniprotkb:EVI1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein homolog(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein(gene name synonym)|uniprotkb:Myelodysplasia syndrome-associated protein 1(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:PRDM3(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285465|imex:IM-26899-17	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005232.2|refseq:XP_005247272.1|ensembl:ENSG00000085276.19(gene)|ensembl:ENST00000494292.6(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0032259""(methylation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0046872""(metal ion binding)|go:""GO:0046974""(histone H3K9 methyltransferase activity)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070828""(heterochromatin organization)|go:""GO:0071425""(hematopoietic stem cell proliferation)|go:""GO:0140938""(histone H3 methyltransferase activity)|go:""GO:0140947""(histone H3K9me2 methyltransferase activity)|go:""GO:0140948""(histone H3K9 monomethyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044411|interpro:IPR046341|interpro:IPR050331|mint:Q03112|rcsb pdb:6BW3|reactome:R-HSA-3214841|reactome:R-HSA-8943724|reactome:R-HSA-9830364|refseq:NP_001098547.3|refseq:NP_001098548.2|refseq:NP_001157471.1|refseq:NP_001157472.1|refseq:NP_001192123.1|refseq:NP_004982.2|refseq:XP_005247276.1|refseq:XP_005247277.1|refseq:XP_005247278.1|refseq:XP_005247280.1|refseq:XP_016861363.1|refseq:XP_016861364.1|refseq:XP_016861365.1|dip:DIP-38639N|panther:PTHR24393(orthology-group)|efo:""Orphanet:402020""|efo:""Orphanet:71289"""	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:MAlEIuVZS4+BNoy50jejv2O30WA9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:49D268EE068A4882|rigid:eNQSCi1Sr4jE3nm1UCUlkgjxfkQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O14786	uniprotkb:Q83DE4	intact:EBI-1187100|uniprotkb:O60461|uniprotkb:Q96IH5|uniprotkb:Q5T7F2|uniprotkb:Q5T7F3|uniprotkb:B0LPG9|uniprotkb:Q86T59|uniprotkb:Q5T7F1|uniprotkb:Q96I90|ensembl:ENSP00000265371.3|ensembl:ENSP00000364001.2	intact:EBI-21285423	psi-mi:nrp1_human(display_long)|uniprotkb:Vascular endothelial cell growth factor 165 receptor(gene name synonym)|uniprotkb:NRP1(gene name)|psi-mi:NRP1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:VEGF165R(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285471|imex:IM-26899-111	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001019800.1|refseq:NP_001019799.1|refseq:NP_003864.4|panther:PTHR46806(orthology-group)|refseq:NP_001316997.1|dip:DIP-5743N|rcsb pdb:2QQN|ensembl:ENSG00000099250.18(gene)|ensembl:ENST00000265371.8(transcript)|ensembl:ENST00000374867.7(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001569""(branching involved in blood vessel morphogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001755""(neural crest cell migration)|go:""GO:0001764""(neuron migration)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002116""(semaphorin receptor complex)|go:""GO:0003148""(outflow tract septum morphogenesis)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005883""(neurofilament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007411""(axon guidance)|go:""GO:0007413""(axonal fasciculation)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008201""(heparin binding)|go:""GO:0009611""(response to wounding)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|rcsb pdb:3I97|go:""GO:0015026""(coreceptor activity)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0019838""(growth factor binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0021612""(facial nerve structural organization)|go:""GO:0021637""(trigeminal nerve structural organization)|go:""GO:0021649""(vestibulocochlear nerve structural organization)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021828""(gonadotrophin-releasing hormone neuronal migration to the hypothalamus)|go:""GO:0030424""(axon)|go:""GO:0030947""(regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031290""(retinal ganglion cell axon guidance)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032489""(regulation of Cdc42 protein signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035767""(endothelial cell chemotaxis)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0036486""(ventral trunk neural crest cell migration)|go:""GO:0038085""(vascular endothelial growth factor binding)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0038190""(VEGF-activated neuropilin signaling pathway)|go:""GO:0043005""(neuron projection)|go:""GO:0043235""(receptor complex)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048842""(positive regulation of axon extension involved in axon guidance)|go:""GO:0048843""(negative regulation of axon extension involved in axon guidance)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0048846""(axon extension involved in axon guidance)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0060385""(axonogenesis involved in innervation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0060666""(dichotomous subdivision of terminal units involved in salivary gland branching)|go:""GO:0060978""(angiogenesis involved in coronary vascular morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061299""(retina vasculature morphogenesis in camera-type eye)|go:""GO:0061441""(renal artery morphogenesis)|go:""GO:0061549""(sympathetic ganglion development)|go:""GO:0061551""(trigeminal ganglion development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071679""(commissural neuron axon guidance)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0097102""(endothelial tip cell fate specification)|go:""GO:0097374""(sensory neuron axon guidance)|go:""GO:0097443""(sorting endosome)|go:""GO:0097475""(motor neuron migration)|go:""GO:0097490""(sympathetic neuron projection extension)|go:""GO:0097491""(sympathetic neuron projection guidance)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099173""(postsynapse organization)|go:""GO:0150018""(basal dendrite development)|go:""GO:0150020""(basal dendrite arborization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1902946""(protein localization to early endosome)|go:""GO:1903375""(facioacoustic ganglion development)|go:""GO:1904835""(dorsal root ganglion morphogenesis)|go:""GO:1905040""(otic placode development)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000859(CUB)|interpro:IPR000998(MAM)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014648(Neuropilin)|interpro:IPR022579|interpro:IPR035914|interpro:IPR050633|mint:O14786|rcsb pdb:1KEX|rcsb pdb:2QQI|rcsb pdb:2QQM|rcsb pdb:4DEQ|rcsb pdb:4RN5|rcsb pdb:5C7G|rcsb pdb:5IJR|rcsb pdb:5IYY|rcsb pdb:5J1X|rcsb pdb:5JGI|rcsb pdb:5JGQ|rcsb pdb:5JHK|rcsb pdb:5L73|rcsb pdb:6FMC|rcsb pdb:6FMF|rcsb pdb:6TKK|rcsb pdb:7JJC|rcsb pdb:7O1N|rcsb pdb:7P5U|rcsb pdb:8C5G|rcsb pdb:8PFE|rcsb pdb:9EOU|reactome:R-HSA-194306|reactome:R-HSA-376176|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-445144|reactome:R-HSA-447041|reactome:R-HSA-9694614"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/27	rogid:q8i8R/AetWNGkscqBWAJPHhmF+E9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:68FAA3386114ED80|rigid:Qnf4i42DM2iiAqeBpWtjFSJK3Bw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96PY5	uniprotkb:Q83DE4	intact:EBI-3438448|uniprotkb:Q8N3E0|uniprotkb:Q4ZG52|uniprotkb:Q14CC9|uniprotkb:B2RZH5	intact:EBI-21285423	psi-mi:fmnl2_human(display_long)|uniprotkb:FMNL2(gene name)|psi-mi:FMNL2(display_short)|uniprotkb:FHOD2(gene name synonym)|uniprotkb:KIAA1902(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 2(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285453|imex:IM-26899-15	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR043592|refseq:NP_443137.2|interpro:IPR016024(Armadillo-type fold)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR014768(GTPase-binding/formin homology 3)|mint:Q96PY5|interpro:IPR042201|interpro:IPR011989(Armadillo-like helical)|go:""GO:0005829""(cytosol)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016477""(cell migration)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0051015""(actin filament binding)|rcsb pdb:4YC7|reactome:R-HSA-5663220|reactome:R-HSA-9013106|reactome:R-HSA-9013148|panther:PTHR45857(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:My1jgXVf11giGBKinod/inR4HH49606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:75447DB44049BE35|rigid:BLjntn/o5sh8JBC8fxURcuEdHw0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NUP9	uniprotkb:Q83DE4	intact:EBI-1171517|ensembl:ENSP00000278193.2	intact:EBI-21285423	psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285459|imex:IM-26899-647	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060832.1|panther:PTHR14063(orthology-group)|ensembl:ENSG00000148943.12(gene)|ensembl:ENST00000278193.7(transcript)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006887""(exocytosis)|go:""GO:0007269""(neurotransmitter secretion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015031""(protein transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0045202""(synapse)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0097016""(L27 domain binding)|go:""GO:0097025""(MPP7-DLG1-LIN7 complex)|go:""GO:0098793""(presynapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|interpro:IPR051109|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:6973A7657A6A812F|rigid:hSTd/VycxbFX5I0w0139tjMI0AU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P62714	uniprotkb:Q83DE4	intact:EBI-1044367|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5|ensembl:ENSP00000221138.4	intact:EBI-21285423	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285483|imex:IM-26899-113	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001009552.1|dip:DIP-42325N|ensembl:ENSG00000104695.13(gene)|ensembl:ENST00000221138.9(transcript)|go:""GO:0000159""(protein phosphatase type 2A complex)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000922""(spindle pole)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008637""(apoptotic mitochondrial changes)|go:""GO:0010288""(response to lead ion)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035970""(peptidyl-threonine dephosphorylation)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0046580""(negative regulation of Ras protein signal transduction)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046872""(metal ion binding)|go:""GO:0048156""(tau protein binding)|go:""GO:0070262""(peptidyl-serine dephosphorylation)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1904528""(positive regulation of microtubule binding)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186(""Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase"")|interpro:IPR029052|interpro:IPR047129|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-9833482|panther:PTHR45619(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/27	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:909FE8A938B2F01F|rigid:+QHX2poJGJQPN1OJ9hvwKoqC/jQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H2B2	uniprotkb:Q83DE4	intact:EBI-751132|uniprotkb:Q9P2K4|uniprotkb:B4DEU3|ensembl:ENSP00000255224.2	intact:EBI-21285423	psi-mi:syt4_human(display_long)|uniprotkb:Synaptotagmin IV(gene name synonym)|uniprotkb:SYT4(gene name)|psi-mi:SYT4(display_short)|uniprotkb:KIAA1342(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285507|imex:IM-26899-229	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_065834.1|ensembl:ENSG00000132872.12(gene)|ensembl:ENST00000255224.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000149""(SNARE binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006906""(vesicle fusion)|go:""GO:0007613""(memory)|go:""GO:0014049""(positive regulation of glutamate secretion)|go:""GO:0014059""(regulation of dopamine secretion)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017158""(regulation of calcium ion-dependent exocytosis)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030154""(cell differentiation)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0032127""(dense core granule membrane)|go:""GO:0033604""(negative regulation of catecholamine secretion)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045202""(synapse)|go:""GO:0045955""(negative regulation of calcium ion-dependent exocytosis)|go:""GO:0045956""(positive regulation of calcium ion-dependent exocytosis)|go:""GO:0048174""(negative regulation of short-term neuronal synaptic plasticity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050709""(negative regulation of protein secretion)|go:""GO:0061891""(calcium ion sensor activity)|go:""GO:0070382""(exocytic vesicle)|go:""GO:0097449""(astrocyte projection)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098992""(neuronal dense core vesicle)|go:""GO:0099012""(neuronal dense core vesicle membrane)|go:""GO:0099502""(calcium-dependent activation of synaptic vesicle fusion)|go:""GO:0099519""(dense core granule cytoskeletal transport)|go:""GO:0150035""(regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission)|go:""GO:0150044""(regulation of postsynaptic dense core vesicle exocytosis)|go:""GO:1903861""(positive regulation of dendrite extension)|go:""GO:1905415""(positive regulation of dense core granule exocytosis)|go:""GO:1905433""(negative regulation of retrograde trans-synaptic signaling by neuropeptide)|go:""GO:1990742""(microvesicle)|go:""GO:2000301""(negative regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR035892|mint:Q9H2B2|rcsb pdb:1UGK|panther:PTHR10024(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:YPZsSWN/mncWeC+vGJ2YYWbHZfU9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:1F6639736F0DC3D7|rigid:2Tq+DshoPtDb1Inn2+968xrOuIE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9P0K7	uniprotkb:Q83DE4	intact:EBI-1023749|uniprotkb:Q6V1W9|uniprotkb:Q7Z5I4|uniprotkb:Q7Z733|uniprotkb:Q9P2L2|uniprotkb:Q9Y3T5|uniprotkb:E9PED3|intact:EBI-2555698|ensembl:ENSP00000265109.3|ensembl:ENSP00000388725.2|ensembl:ENSP00000422942.1	intact:EBI-21285423	psi-mi:rai14_human(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:RAI14(gene name)|psi-mi:RAI14(display_short)|uniprotkb:KIAA1334(gene name synonym)|uniprotkb:NORPEG(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285495|imex:IM-26899-649	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138992.1|refseq:NP_001138993.1|refseq:NP_001138994.1|refseq:NP_001138995.1|refseq:NP_001138997.1|refseq:NP_056392.2|refseq:XP_011512319.1|refseq:XP_011512320.1|refseq:XP_011512321.1|refseq:XP_011512322.1|refseq:XP_011512323.1|refseq:XP_011512324.1|refseq:XP_006714532.1|refseq:XP_016864824.1|ensembl:ENSG00000039560.14(gene)|ensembl:ENST00000265109.8(transcript)|ensembl:ENST00000428746.6(transcript)|ensembl:ENST00000503673.5(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030154""(cell differentiation)|go:""GO:0070161""(anchoring junction)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR042420|mint:Q9P0K7|panther:PTHR24129(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:m5hQYx6HEi9QEAey1UiNpeAp6tw9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:4DFFE1B497C86244|rigid:/wShsi0zAgeJgtzadFgVS/fBv9Q	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P62191	uniprotkb:Q83DE4	intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|uniprotkb:Q6NW36|uniprotkb:B4DR63|ensembl:ENSP00000261303.8	intact:EBI-21285423	psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285489|imex:IM-26899-227	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002793.2|ensembl:ENSG00000100764.14(gene)|ensembl:ENST00000261303.13(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|refseq:NP_001317141.1|refseq:XP_016876959.1|panther:PTHR23073(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:60C3841C235102D5|rigid:R7OMSz+56r4qIZ3eHLqjGiFtu04	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8NHS9	uniprotkb:Q83DE4	intact:EBI-7067260|ensembl:ENSP00000380354.3|ensembl:ENSP00000459329.1|ensembl:ENSP00000459580.1|ensembl:ENSP00000460187.1|intact:MINT-8201601|uniprotkb:D3DTI9|uniprotkb:J3KN63|uniprotkb:Q96JT4|uniprotkb:Q969H3|uniprotkb:B4DXB1	intact:EBI-21285423	psi-mi:spt22_human(display_long)|uniprotkb:SPATA22(gene name)|psi-mi:SPATA22(display_short)|uniprotkb:Testis development protein NYD-SP20(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285501|imex:IM-26899-749	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000141255.13(gene)|ensembl:ENST00000397168.7(transcript)|ensembl:ENST00000572969.6(transcript)|ensembl:ENST00000573128.5(transcript)|ensembl:ENST00000575375.5(transcript)|go:""GO:0000711""(meiotic DNA repair synthesis)|go:""GO:0005694""(chromosome)|go:""GO:0007129""(homologous chromosome pairing at meiosis)|go:""GO:0009566""(fertilization)|go:""GO:0048137""(spermatocyte division)|go:""GO:0051445""(regulation of meiotic cell cycle)|go:""GO:0061458""(reproductive system development)|interpro:IPR033536|mint:Q8NHS9|refseq:NP_001164167.1|refseq:NP_001164169.1|refseq:NP_115987.2|refseq:NP_001164168.1|refseq:NP_001164166.1|refseq:NP_001164170.1|refseq:NP_001308265.1|refseq:NP_001308266.1|panther:PTHR35258(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	comment:mint|comment:homomint	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:6SGHXJywVk383ITHBKxLAhAfXuE9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:029330C98E6C4C4C|rigid:yh+SmbInX4RQAn3qysZ00od6BuQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q68CP9	uniprotkb:Q83D60	intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044.6	intact:EBI-21285556	psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285580|imex:IM-26899-345	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000189079.18(gene)|ensembl:ENST00000334344.11(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006337""(nucleosome disassembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|interpro:IPR003150(DNA-binding RFX)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0042592""(homeostatic process)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0048568""(embryonic organ development)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|interpro:IPR052406|mint:Q68CP9|rcsb pdb:7VDV|rcsb pdb:7Y8R|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_001334768.1|refseq:NP_689854.2|dip:DIP-33391N|efo:""Orphanet:1465"""	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/17	rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:08A27AEFDFB31E9A|rigid:+TsiYi8O1ve39fliPp/FgOP8wPs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96LL4	uniprotkb:Q83D60	intact:EBI-751596|uniprotkb:Q96LJ9|ensembl:ENSP00000297324.4	intact:EBI-21285556	psi-mi:ch048_human(display_long)|uniprotkb:C8orf48(gene name)|psi-mi:C8orf48(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285592|imex:IM-26899-347	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001007091.1|ensembl:ENSG00000164743.5(gene)|ensembl:ENST00000297324.5(transcript)|interpro:IPR027932|mint:Q96LL4|panther:PTHR35256(orthology-group)	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:JPB4E+42Jc1w9k0ExNOu0GOi9AQ9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:D6C47FD19DD4F05D|rigid:U5sKulx4QWIjFOEb9gySTEL/2A0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8WW43	uniprotkb:Q83D60	intact:EBI-2606497|uniprotkb:Q6UWQ1|uniprotkb:Q9H0S0|uniprotkb:A8K589|uniprotkb:Q564N3|ensembl:ENSP00000261879.5	intact:EBI-21285556	psi-mi:aph1b_human(display_long)|uniprotkb:APH1B(gene name)|psi-mi:APH1B(display_short)|uniprotkb:PSFL(gene name synonym)|uniprotkb:Aph-1beta(gene name synonym)|uniprotkb:Presenilin-stabilization factor-like(gene name synonym)|uniprotkb:UNQ688/PRO1328(orf name)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285574|imex:IM-26899-751	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_112591.2|refseq:NP_001139118.1|ensembl:ENSG00000138613.14(gene)|ensembl:ENST00000261879.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007220""(Notch receptor processing)|go:""GO:0010008""(endosome membrane)|go:""GO:0010950""(positive regulation of endopeptidase activity)|go:""GO:0016020""(membrane)|go:""GO:0016485""(protein processing)|go:""GO:0030133""(transport vesicle)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031293""(membrane protein intracellular domain proteolysis)|go:""GO:0034205""(amyloid-beta formation)|go:""GO:0042987""(amyloid precursor protein catabolic process)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0070765""(gamma-secretase complex)|interpro:IPR009294(Aph-1)|mint:Q8WW43|rcsb pdb:8OQY|rcsb pdb:8OQZ|reactome:R-HSA-1251985|reactome:R-HSA-193692|reactome:R-HSA-205043|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3928665|reactome:R-HSA-9013507|reactome:R-HSA-9013700|reactome:R-HSA-9017802|reactome:R-HSA-977225|reactome:R-HSA-9839383|panther:PTHR12889(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:w8GOGnbWB3OPYAAfOxy/YCzlXPo9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:3A308DF88B7F97C9|rigid:m+jeODlH/zaxu4Xg0simF6VUsv0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96K75	uniprotkb:Q83DE4	intact:EBI-6660752|uniprotkb:Q5JPJ3|ensembl:ENSP00000295208.2|ensembl:ENSP00000405509.1|ensembl:ENSP00000511953.1|ensembl:ENSP00000513894.1|ensembl:ENSP00000513895.1|ensembl:ENSP00000513896.1|ensembl:ENSP00000513897.1	intact:EBI-21285423	psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285513|imex:IM-26899-19	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_116177.1|refseq:XP_006712869.1|refseq:NP_001304934.1|ensembl:ENSG00000144026.14(gene)|ensembl:ENST00000295208.7(transcript)|ensembl:ENST00000411425.1(transcript)|ensembl:ENST00000695481.2(transcript)|ensembl:ENST00000698720.1(transcript)|ensembl:ENST00000698721.1(transcript)|ensembl:ENST00000698722.1(transcript)|ensembl:ENST00000698723.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|panther:PTHR24377(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:2E8617D3B18AA0AB|rigid:s5pEWxoijKNhHtQMjxUJSrsj1n8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BZE7	uniprotkb:Q83D60	intact:EBI-10303102|uniprotkb:Q96M68|uniprotkb:Q5JYU9|ensembl:ENSP00000249079.2|ensembl:ENSP00000384618.1|ensembl:ENSP00000384667.1	intact:EBI-21285556	psi-mi:evg1_human(display_long)|uniprotkb:C22orf23(gene name)|psi-mi:C22orf23(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285586|imex:IM-26899-233	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001193991.1|refseq:NP_115950.3|ensembl:ENSG00000128346.11(gene)|ensembl:ENST00000249079.6(transcript)|ensembl:ENST00000403026.5(transcript)|ensembl:ENST00000403305.6(transcript)|interpro:IPR007914(Protein of unknown function UPF0193)|mint:Q9BZE7|panther:PTHR28348(orthology-group)	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:1/If0SoE7GFjWPn/KgsZ/nF0kfA9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:7039CFC9815C2571|rigid:lisFoAX3E0zza6ytc1pVY/Prp6I	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q02252	uniprotkb:Q83D60	intact:EBI-2107242|uniprotkb:Q9UKM8|uniprotkb:B2R609|uniprotkb:B4DFS8|uniprotkb:J3KNU8|ensembl:ENSP00000450436.1	intact:EBI-21285556	psi-mi:mmsa_human(display_long)|uniprotkb:MMSDH(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 6 member A1(gene name synonym)|uniprotkb:ALDH6A1(gene name)|psi-mi:ALDH6A1(display_short)|uniprotkb:Malonate-semialdehyde dehydrogenase [acylating](gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285562|imex:IM-26899-231	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR43866(orthology-group)|efo:""Orphanet:289307""|ensembl:ENSG00000119711.13(gene)|ensembl:ENST00000553458.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004491""(""methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006210""(thymine catabolic process)|go:""GO:0006573""(valine metabolic process)|go:""GO:0006574""(valine catabolic process)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0018478""(""malonate-semialdehyde dehydrogenase (acetylating) activity"")|go:""GO:0019859""(thymine metabolic process)|go:""GO:0050873""(brown fat cell differentiation)|interpro:IPR010061(Methylmalonate-semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q02252|rcsb pdb:8XXQ|reactome:R-HSA-70895|refseq:NP_001265522.1|refseq:NP_005580.1"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:9tRJSF7S26Z8N2WYcURXRoOLfFw9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:55B766FB070C91FF|rigid:oet4n0j6mWd6tiTSsWnzel81X/Q	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q92527	uniprotkb:Q83D60	intact:EBI-725852|uniprotkb:Q96QN1|uniprotkb:Q9UDM3|uniprotkb:B4DYF5|ensembl:ENSP00000265224.4	intact:EBI-21285556	psi-mi:ankr7_human(display_long)|uniprotkb:Testis-specific protein TSA806(gene name synonym)|uniprotkb:ANKRD7(gene name)|psi-mi:ANKRD7(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285568|imex:IM-26899-123	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_062618.2|ensembl:ENSG00000106013.15(gene)|ensembl:ENST00000265224.9(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR050657|mint:Q92527|panther:PTHR24147(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:uytbHTgjbeon7IxDmO/PD8ZcXtM9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:375D08AE91951879|rigid:QGOWZYWxjXqT6fsKDxTwfWV+uE4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y6W3	uniprotkb:Q83D60	intact:EBI-1765641|ensembl:ENSP00000253693.2	intact:EBI-21285556	psi-mi:can7_human(display_long)|uniprotkb:CAPN7(gene name)|psi-mi:CAPN7(display_short)|uniprotkb:PALBH(gene name synonym)|uniprotkb:PalB homolog(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285598|imex:IM-26899-651	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055111.1|ensembl:ENSG00000131375.10(gene)|ensembl:ENST00000253693.7(transcript)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004198""(calcium-dependent cysteine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090541""(MIT domain binding)|go:""GO:0097264""(self proteolysis)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR007330(MIT)|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR036181|interpro:IPR036213|interpro:IPR038765|interpro:IPR051297|mint:Q9Y6W3|rcsb pdb:2QFE|rcsb pdb:8UC6|reactome:R-HSA-1474228|panther:PTHR46143(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:tRDBeVQRu1tuCDWtSrve/Y9lWsg9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:6644655202CFEA06|rigid:DyutS351B8hRDyyp+xK8AdyZP3M	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14966	uniprotkb:Q83DE4	intact:EBI-742207|uniprotkb:B5MDV1|uniprotkb:Q5XJ05|uniprotkb:Q53R34|uniprotkb:Q68DP3|uniprotkb:Q6P2H2|uniprotkb:Q7Z3T7|uniprotkb:Q8NF92|uniprotkb:Q8TCA1|uniprotkb:Q9H2G1|uniprotkb:Q9NP37|uniprotkb:B7ZLD1|uniprotkb:A0A096LPH6|ensembl:ENSP00000264447.4|ensembl:ENSP00000386433.1	intact:EBI-21285423	psi-mi:zn638_human(display_long)|uniprotkb:ZNF638(gene name)|psi-mi:ZNF638(display_short)|uniprotkb:NP220(gene name synonym)|uniprotkb:ZFML(gene name synonym)|uniprotkb:Zinc finger matrin-like protein(gene name synonym)|uniprotkb:Nuclear protein 220(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se33-1(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285550|imex:IM-26899-121	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001014972.1|refseq:NP_055312.2|refseq:NP_001239541.1|refseq:NP_001239542.1|dip:DIP-42386N|ensembl:ENSG00000075292.20(gene)|ensembl:ENST00000264447.9(transcript)|ensembl:ENST00000409544.5(transcript)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043484""(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR033096|interpro:IPR035979|interpro:IPR036236|mint:Q14966|rcsb pdb:6SXW|reactome:R-HSA-381340|panther:PTHR15592(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:KkoO3Hgmx9CwI4LgVmk2ankakIY9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:47CDF44C6C91DAD5|rigid:FjIfhat8ElR1ifZnOyjlVgrdRoo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96ND8	uniprotkb:Q83DE4	intact:EBI-21285519|ensembl:ENSP00000291598.7|ensembl:ENSP00000388502.2|uniprotkb:O14850|uniprotkb:Q2NKK3	intact:EBI-21285423	psi-mi:zn583_human(display_long)|uniprotkb:ZNF583(gene name)|psi-mi:ZNF583(display_short)|uniprotkb:Zinc finger protein L3-5(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285544|imex:IM-26899-343	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000198440.9(gene)|ensembl:ENST00000291598.11(transcript)|ensembl:ENST00000333201.13(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96ND8|reactome:R-HSA-212436|refseq:NP_001153332.1|refseq:NP_001153333.1|refseq:NP_689691.2|refseq:XP_011524819.1|refseq:XP_016881839.1|panther:PTHR24377(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:K5sTOQhO2w/s5N/S+t9aFNGP/Ns9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:0CDBD2681B606656|rigid:+yL4MNs50rgEnydBlD4VfoBYthw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P12259	uniprotkb:Q83D60	intact:EBI-9640912|uniprotkb:A8K6E8|uniprotkb:Q14285|uniprotkb:Q5R346|uniprotkb:Q8WWQ6|uniprotkb:Q6UPU6|uniprotkb:Q2EHR5|uniprotkb:Q5R347|ensembl:ENSP00000356771.3	intact:EBI-21285556	psi-mi:fa5_human(display_long)|uniprotkb:F5(gene name)|psi-mi:F5(display_short)|uniprotkb:Activated protein C cofactor(gene name synonym)|uniprotkb:Proaccelerin, labile factor(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285652|imex:IM-26899-239	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-47331N|ensembl:ENSG00000198734.12(gene)|ensembl:ENST00000367797.9(transcript)|go:""GO:0005507""(copper ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007596""(blood coagulation)|go:""GO:0008015""(blood circulation)|go:""GO:0016020""(membrane)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0032571""(response to vitamin K)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR024715|interpro:IPR033138|interpro:IPR050633|mint:P12259|rcsb pdb:1CZS|rcsb pdb:1CZT|rcsb pdb:1CZV|rcsb pdb:3P6Z|rcsb pdb:3P70|rcsb pdb:3S9C|rcsb pdb:7KVE|rcsb pdb:7KVF|rcsb pdb:7KXY|rcsb pdb:7TPP|rcsb pdb:8FDG|rcsb pdb:8TN9|rcsb pdb:9CTH|reactome:R-HSA-114608|reactome:R-HSA-140875|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-8957275|refseq:NP_000121.2|efo:""Orphanet:131""|efo:""Orphanet:326""|efo:""Orphanet:329217""|efo:""Orphanet:391320""|panther:PTHR24543(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:i1+4mzlwzNvSHZ2CketeTEvnJEQ9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:61BD57266F41930B|rigid:nTivqtnHuL9ph/1RxTza4T4lQ28	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q58WW2	uniprotkb:Q83D60	intact:EBI-2559044|ensembl:ENSP00000311949.6|uniprotkb:Q8TB19|uniprotkb:Q8IXH3|uniprotkb:A2A295|uniprotkb:Q7L8I0|uniprotkb:B4DNB8	intact:EBI-21285556	psi-mi:dcaf6_human(display_long)|uniprotkb:DCAF6(gene name)|psi-mi:DCAF6(display_short)|uniprotkb:IQWD1(gene name synonym)|uniprotkb:Nuclear receptor interaction protein(gene name synonym)|uniprotkb:IQ motif and WD repeat-containing protein 1(gene name synonym)|uniprotkb:Androgen receptor complex-associated protein(gene name synonym)|uniprotkb:MSTP055(orf name)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285628|imex:IM-26899-655	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143164.16(gene)|ensembl:ENST00000312263.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR045151|mint:Q58WW2|rcsb pdb:3I7O|reactome:R-HSA-8951664|refseq:NP_001017977.1|refseq:NP_001185885.1|refseq:NP_001185886.1|refseq:NP_060912.2|dip:DIP-44678N|panther:PTHR15574(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/25	rogid:1CtoPWPj6fdryvDlC46pXiUguDc9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:5C36515FE5689471|rigid:SL2YGhKlOaBwieGivUD22hIBeA4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BT78	uniprotkb:Q83D60	intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|uniprotkb:B3KST5|ensembl:ENSP00000264389.2	intact:EBI-21285556	psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285622|imex:IM-26899-457	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057213.2|refseq:NP_001244935.1|refseq:NP_001317656.1|dip:DIP-34516N|ensembl:ENSG00000138663.9(gene)|ensembl:ENST00000264389.7(transcript)|go:""GO:0000338""(protein deneddylation)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0016607""(nuclear speck)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0030054""(cell junction)|go:""GO:0045116""(protein neddylation)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR041406|interpro:IPR054559|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:8H38|rcsb pdb:8H3A|rcsb pdb:8H3F|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|panther:PTHR10855(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/26	rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:D646F48ED94B4E54|rigid:wOEf7H3omLaZgFxS7esWxwzJ+XY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P78371	uniprotkb:Q83D60	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300.6	intact:EBI-21285556	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 2(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285610|imex:IM-26899-653	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11353(orthology-group)|refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226.13(gene)|ensembl:ENST00000299300.11(transcript)|go:""GO:0002199""(zona pellucida receptor complex)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044297""(cell body)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090666""(scaRNA localization to Cajal body)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR053374|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7TUB|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHD|rcsb pdb:8SHE|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/26	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:D8914959D5F12EF9|rigid:Tlk7Df2M/I+gg1vW7QVn0YHXn8k	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O00399	uniprotkb:Q83D60	intact:EBI-2559415|ensembl:ENSP00000221114.3|uniprotkb:B2RAC1	intact:EBI-21285556	psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285634|imex:IM-26899-565	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000104671.8(gene)|ensembl:ENST00000221114.8(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0070840""(dynein complex binding)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|refseq:NP_006562.1|panther:PTHR13072(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/28	rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:132871E96CA20E59|rigid:EfaYGRCh3l3nsqovsatet4tcr0M	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O00299	uniprotkb:Q83D60	intact:EBI-347404|uniprotkb:Q15089|uniprotkb:Q502X1|ensembl:ENSP00000364934.2|ensembl:ENSP00000364935.2|ensembl:ENSP00000364940.3|ensembl:ENSP00000372896.2|ensembl:ENSP00000372897.2|ensembl:ENSP00000379229.1|ensembl:ENSP00000382926.3|ensembl:ENSP00000382931.1|ensembl:ENSP00000391395.1|ensembl:ENSP00000398056.2|ensembl:ENSP00000400280.1|ensembl:ENSP00000400532.1|ensembl:ENSP00000401292.2|ensembl:ENSP00000404037.1|ensembl:ENSP00000404589.1|ensembl:ENSP00000406088.1|ensembl:ENSP00000406335.2|ensembl:ENSP00000406968.1|ensembl:ENSP00000407429.2|ensembl:ENSP00000407791.2|ensembl:ENSP00000408094.1|ensembl:ENSP00000408357.1|ensembl:ENSP00000409247.1|ensembl:ENSP00000409979.1|ensembl:ENSP00000410965.1|ensembl:ENSP00000412217.1|ensembl:ENSP00000413330.1|ensembl:ENSP00000416211.1|ensembl:ENSP00000477623.1|ensembl:ENSP00000478930.1|ensembl:ENSP00000479501.1|ensembl:ENSP00000479808.1|ensembl:ENSP00000480256.1|ensembl:ENSP00000482255.1|ensembl:ENSP00000484581.1	intact:EBI-21285556	psi-mi:clic1_human(display_long)|uniprotkb:CLIC1(gene name)|psi-mi:CLIC1(display_short)|uniprotkb:NCC27(gene name synonym)|uniprotkb:Nuclear chloride ion channel 27(gene name synonym)|uniprotkb:Chloride channel ABP(gene name synonym)|uniprotkb:Regulatory nuclear chloride ion channel protein(gene name synonym)|uniprotkb:G6(gene name synonym)|uniprotkb:Glutaredoxin-like oxidoreductase CLIC1(gene name synonym)|uniprotkb:Glutathione-dependent dehydroascorbate reductase CLIC1(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285616|imex:IM-26899-125	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001279.2|refseq:NP_001274522.1|refseq:NP_001274523.1|panther:PTHR43920(orthology-group)|ensembl:ENSG00000206394.8(gene)|ensembl:ENSG00000213719.8(gene)|ensembl:ENSG00000223639.6(gene)|ensembl:ENSG00000226248.6(gene)|ensembl:ENSG00000226417.6(gene)|ensembl:ENSG00000226651.6(gene)|ensembl:ENSG00000230685.6(gene)|ensembl:ENST00000375779.6(transcript)|ensembl:ENST00000375780.6(transcript)|ensembl:ENST00000375784.8(transcript)|ensembl:ENST00000383404.6(transcript)|ensembl:ENST00000383405.6(transcript)|ensembl:ENST00000395892.5(transcript)|ensembl:ENST00000400052.7(transcript)|ensembl:ENST00000400058.5(transcript)|ensembl:ENST00000415179.5(transcript)|ensembl:ENST00000418285.6(transcript)|ensembl:ENST00000420458.5(transcript)|ensembl:ENST00000422167.6(transcript)|ensembl:ENST00000423055.5(transcript)|ensembl:ENST00000423143.5(transcript)|ensembl:ENST00000423804.5(transcript)|ensembl:ENST00000425464.6(transcript)|ensembl:ENST00000431921.5(transcript)|ensembl:ENST00000433916.5(transcript)|ensembl:ENST00000434202.5(transcript)|ensembl:ENST00000435242.5(transcript)|ensembl:ENST00000438708.5(transcript)|ensembl:ENST00000438750.5(transcript)|ensembl:ENST00000442045.5(transcript)|ensembl:ENST00000447338.5(transcript)|ensembl:ENST00000447369.5(transcript)|ensembl:ENST00000451546.5(transcript)|ensembl:ENST00000456863.6(transcript)|ensembl:ENST00000457485.6(transcript)|ensembl:ENST00000614673.1(transcript)|ensembl:ENST00000614982.1(transcript)|ensembl:ENST00000616760.1(transcript)|ensembl:ENST00000618288.1(transcript)|ensembl:ENST00000619727.1(transcript)|ensembl:ENST00000621055.1(transcript)|ensembl:ENST00000622613.1(transcript)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0006821""(chloride transport)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031982""(vesicle)|go:""GO:0034707""(chloride channel complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0072562""(blood microparticle)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030259|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|interpro:IPR053823|mint:O00299|rcsb pdb:1K0M|rcsb pdb:1K0N|rcsb pdb:1K0O|rcsb pdb:1RK4|rcsb pdb:3O3T|rcsb pdb:3P8W|rcsb pdb:3P90|rcsb pdb:3QR6|rcsb pdb:3SWL|rcsb pdb:3TGZ|rcsb pdb:3UVH|rcsb pdb:4IQA|rcsb pdb:4JZQ|rcsb pdb:4K0G|rcsb pdb:4K0N|rcsb pdb:7F8R|rcsb pdb:7FBQ"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:HVux62IcNdqcPgqmlGlIyZTLpFo9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:93D6BB3F75978649|rigid:T24+LUhe6DOeg5Y+CuowJSooCCk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5TID7	uniprotkb:Q83D60	intact:EBI-7267656|uniprotkb:Q8TC48|uniprotkb:O60780|intact:MINT-1193587|uniprotkb:Q53FD5|uniprotkb:Q5TID9|ensembl:ENSP00000356780.3	intact:EBI-21285556	psi-mi:cc181_human(display_long)|uniprotkb:CCDC181(gene name)|psi-mi:CCDC181(display_short)|uniprotkb:C1orf114(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285604|imex:IM-26899-455	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011508129.1|refseq:NP_067002.1|refseq:XP_005245440.1|refseq:XP_016857427.1|refseq:XP_016857428.1|refseq:XP_016857429.1|refseq:NP_001287897.1|refseq:NP_001287898.1|panther:PTHR14320(orthology-group)|ensembl:ENSG00000117477.13(gene)|ensembl:ENST00000367806.8(transcript)|go:""GO:0002177""(manchette)|go:""GO:0005737""(cytoplasm)|go:""GO:0005874""(microtubule)|go:""GO:0008017""(microtubule binding)|go:""GO:0036126""(sperm flagellum)|interpro:IPR026687|mint:Q5TID7"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	comment:mint|comment:homomint	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:z5m86YqgyvVxXNxAwByvwx8iYNI9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:21E907C0A4919DB8|rigid:0z0GCGwCJBSSUI4rMNP+XL9aFsU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TC29	uniprotkb:Q83D60	intact:EBI-9246952|uniprotkb:A8K8Y0|uniprotkb:D3DRV2|ensembl:ENSP00000331044.4|ensembl:ENSP00000432930.1	intact:EBI-21285556	psi-mi:enkur_human(display_long)|uniprotkb:ENKUR(gene name)|psi-mi:ENKUR(display_short)|uniprotkb:C10orf63(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285646|imex:IM-26899-237	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001257312.1|refseq:NP_659447.1|refseq:XP_011517650.1|ensembl:ENST00000331161.9(transcript)|ensembl:ENST00000496261.6(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005879""(axonemal microtubule)|ensembl:ENSG00000151023.17(gene)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0036126""(sperm flagellum)|go:""GO:0061966""(establishment of left/right asymmetry)|go:""GO:0097228""(sperm principal piece)|go:""GO:0097728""(9+0 motile cilium)|go:""GO:0097729""(9+2 motile cilium)|go:""GO:0160112""(axonemal B tubule inner sheath)|interpro:IPR027012|interpro:IPR052102|mint:Q8TC29|rcsb pdb:7UNG|rcsb pdb:8J07|panther:PTHR21490(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:N9U7aJBZ/aBSi1boD3iQZfyWAbA9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:0318F916FDEE587A|rigid:QOOjQ7Xvhd2VhH63Ir61jAVmtnM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TCE6	uniprotkb:Q83D60	intact:EBI-725416|uniprotkb:Q9NXW4|uniprotkb:B1AMV6|uniprotkb:B4DDC3|uniprotkb:D3DRC8|ensembl:ENSP00000354688.2	intact:EBI-21285556	psi-mi:den10_human(display_long)|uniprotkb:DENND10(gene name)|psi-mi:DENND10(display_short)|uniprotkb:FAM45A(gene name synonym)|uniprotkb:Protein FAM45A(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285658|imex:IM-26899-21	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_996892.1|refseq:NP_001290040.1|refseq:NP_001290041.1|refseq:NP_001290042.1|refseq:XP_016871750.1|refseq:XP_016871751.1|refseq:XP_016871752.1|ensembl:ENSG00000119979.18(gene)|ensembl:ENST00000361432.3(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005770""(late endosome)|go:""GO:0015031""(protein transport)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032509""(endosome transport via multivesicular body sorting pathway)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR037516|interpro:IPR042431|mint:Q8TCE6|rcsb pdb:8P0V|panther:PTHR28544(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:y2TwrFW/ss6WtsUMVIVRCG8lEKk9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:67FF14D1BDE54073|rigid:CRC0QfaenXbT9ZEB5DYZRM8zBzo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5JVL4	uniprotkb:Q83D60	intact:EBI-743105|uniprotkb:Q5XKM4|uniprotkb:Q6E1U7|uniprotkb:Q6E1U8|uniprotkb:Q8WUL2|uniprotkb:Q9NVW6|uniprotkb:B4DMU3|uniprotkb:F5GZD8|intact:EBI-11099619|ensembl:ENSP00000360107.4	intact:EBI-21285556	psi-mi:efhc1_human(display_long)|uniprotkb:EFHC1(gene name)|psi-mi:EFHC1(display_short)|uniprotkb:Myoclonin-1(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285640|imex:IM-26899-235	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1941""|efo:""Orphanet:307""|ensembl:ENSG00000096093.16(gene)|ensembl:ENST00000371068.11(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0000922""(spindle pole)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005813""(centrosome)|go:""GO:0005879""(axonemal microtubule)|go:""GO:0005930""(axoneme)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0036126""(sperm flagellum)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0051302""(regulation of cell division)|go:""GO:0060285""(cilium-dependent cell motility)|go:""GO:0072686""(mitotic spindle)|go:""GO:0160111""(axonemal A tubule inner sheath)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|mint:Q5JVL4|rcsb pdb:7UNG|rcsb pdb:8J07|refseq:NP_001165891.1|refseq:NP_060570.2|panther:PTHR12086(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:l5I5K4Lgihe08j5BuPBk4uDY+qk9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:22F03389D1BF63DD|rigid:0I1OEHD17+5v0ClLdq5V/RPS5Q4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NXN4	uniprotkb:Q83D60	intact:EBI-10316460|ensembl:ENSP00000358451.4|uniprotkb:Q96DZ0	intact:EBI-21285556	psi-mi:gdap2_human(display_long)|uniprotkb:GDAP2(gene name)|psi-mi:GDAP2(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285682|imex:IM-26899-131	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000196505.11(gene)|ensembl:ENST00000369443.10(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0032526""(response to retinoic acid)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR035793|interpro:IPR036865|interpro:IPR043472|mint:Q9NXN4|rcsb pdb:4UML|refseq:NP_001129061.1|refseq:NP_060156.1|panther:PTHR11106(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:2fjIQzKGImu2CwNw2ul5gti/28g9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:DD9485896118CEB5|rigid:a89t1FSvlGWGh/UMdVF4fI3ASiI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8WYA0	uniprotkb:Q83D60	intact:EBI-11321879|uniprotkb:Q8NB51|uniprotkb:Q9UNY8|uniprotkb:Q2YDY1|uniprotkb:Q9BSV2|ensembl:ENSP00000242591.5|ensembl:ENSP00000449718.1	intact:EBI-21285556	psi-mi:ift81_human(display_long)|uniprotkb:IFT81(gene name)|psi-mi:IFT81(display_short)|uniprotkb:CDV1(gene name synonym)|uniprotkb:Carnitine deficiency-associated protein expressed in ventricle 1(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285706|imex:IM-26899-661	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_016874706.1|ensembl:ENSG00000122970.16(gene)|ensembl:ENST00000242591.10(transcript)|ensembl:ENST00000552912.5(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005929""(cilium)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008589""(regulation of smoothened signaling pathway)|go:""GO:0015631""(tubulin binding)|go:""GO:0030992""(intraciliary transport particle B)|go:""GO:0031514""(motile cilium)|go:""GO:0035720""(intraciliary anterograde transport)|go:""GO:0035735""(intraciliary transport involved in cilium assembly)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042073""(intraciliary transport)|go:""GO:0060271""(cilium assembly)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097228""(sperm principal piece)|go:""GO:0097542""(ciliary tip)|go:""GO:0120316""(sperm flagellum assembly)|interpro:IPR029600|interpro:IPR041146|interpro:IPR043016|mint:Q8WYA0|reactome:R-HSA-5620924|panther:PTHR15614(orthology-group)|refseq:NP_001137251.1|refseq:NP_001334875.1|refseq:NP_054774.2|refseq:NP_113661.2"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:2+081wYMeK1gK+kuJRx3DFuiaGU9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:68B789DFC8215564|rigid:1BeFVSzvfWgRt/h6q4f+BXs0Cy4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5TBA9	uniprotkb:Q83D60	intact:EBI-2816917|uniprotkb:Q9Y3N6|ensembl:ENSP00000445043.2|intact:EBI-28984104	intact:EBI-21285556	psi-mi:fry_human(display_long)|uniprotkb:FRY(gene name)|psi-mi:FRY(display_short)|uniprotkb:C13orf14(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285670|imex:IM-26899-127	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_075463.2|ensembl:ENSG00000073910.23(gene)|ensembl:ENST00000542859.6(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0000922""(spindle pole)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005813""(centrosome)|go:""GO:0005938""(cell cortex)|go:""GO:0030427""(site of polarized growth)|go:""GO:0031175""(neuron projection development)|go:""GO:1904428""(negative regulation of tubulin deacetylation)|interpro:IPR025481|interpro:IPR025614|interpro:IPR029473|interpro:IPR039867|interpro:IPR045842|mint:Q5TBA9|panther:PTHR12295(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:XSGKUpD+VVyYJ1ew69qbPQnoJWg9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:4186255300D4BD03|rigid:imlLBFnUrLm+NVt/aXIYSTIviug	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NP50	uniprotkb:Q83D60	intact:EBI-741906|uniprotkb:Q9BSZ8|uniprotkb:D3DUV8|ensembl:ENSP00000337477.4|ensembl:ENSP00000393279.2|ensembl:ENSP00000479093.1|ensembl:ENSP00000488570.1	intact:EBI-21285556	psi-mi:shcaf_human(display_long)|uniprotkb:SINHCAF(gene name)|psi-mi:SINHCAF(display_short)|uniprotkb:C12orf14(gene name synonym)|uniprotkb:FAM60A(gene name synonym)|uniprotkb:Protein FAM60A(gene name synonym)|uniprotkb:Tera protein homolog(gene name synonym)|uniprotkb:L4(orf name)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285664|imex:IM-26899-461	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001129283.1|refseq:NP_001129284.1|refseq:NP_067061.1|refseq:XP_016875247.1|refseq:XP_016875248.1|refseq:XP_016875249.1|refseq:XP_016875250.1|refseq:XP_016875251.1|ensembl:ENSG00000139146.14(gene)|ensembl:ENSG00000276371.2(gene)|ensembl:ENST00000337682.9(transcript)|ensembl:ENST00000454658.6(transcript)|ensembl:ENST00000617411.2(transcript)|ensembl:ENST00000633702.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0005634""(nucleus)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0070822""(Sin3-type complex)|go:""GO:1902455""(negative regulation of stem cell population maintenance)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR026065|mint:Q9NP50|refseq:XP_011519105.1|panther:PTHR13422(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:LVESO8KQhobNYQduBQ/iAmNaNTM9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:E34908BDDF0E07A2|rigid:UJqXZov6x8YBXcn0B7qOGuDBNCk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q83D60	uniprotkb:P50395	intact:EBI-21285556	intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|uniprotkb:Q5SX88|ensembl:ENSP00000369538.4	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285688|imex:IM-26899-753	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	"refseq:NP_001108628.1|refseq:NP_001485.2|dip:DIP-50593N|ensembl:ENSG00000057608.18(gene)|ensembl:ENST00000380191.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005093""(Rab GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031982""(vesicle)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0045202""(synapse)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902018""(negative regulation of cilium assembly)|go:""GO:1903565""(negative regulation of protein localization to cilium)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|panther:PTHR11787(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/28	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606	intact-crc:C9E824C327026226|rigid:aYKuzChPjJuXwRm6QLGFVVUuPsU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13123	uniprotkb:Q83D60	intact:EBI-713456|uniprotkb:Q6IPD8|ensembl:ENSP00000396301.2	intact:EBI-21285556	psi-mi:red_human(display_long)|uniprotkb:Protein RER(gene name synonym)|uniprotkb:IK factor(gene name synonym)|uniprotkb:Cytokine IK(gene name synonym)|uniprotkb:IK(gene name)|psi-mi:IK(display_short)|uniprotkb:RED(gene name synonym)|uniprotkb:RER(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285712|imex:IM-26899-23	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006074.2|ensembl:ENSG00000113141.19(gene)|ensembl:ENST00000417647.7(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000922""(spindle pole)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0016607""(nuclear speck)|go:""GO:0034501""(protein localization to kinetochore)|go:""GO:0042802""(identical protein binding)|go:""GO:0071005""(U2-type precatalytic spliceosome)|interpro:IPR012492(RED-like, C-terminal)|interpro:IPR012916(RED-like, N-terminal)|interpro:IPR039896|mint:Q13123|rcsb pdb:5O9Z|rcsb pdb:6Q8I|rcsb pdb:8QO9|rcsb pdb:8QZS|reactome:R-HSA-72163|panther:PTHR12765(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:EBUQl+Gj0ozHP85Uh4xc9q2Vr6Y9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:47E56C12B924BAF2|rigid:5M0PxBJlIH/Dlby/jw9f6QOmTi0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P04066	uniprotkb:Q83D60	intact:EBI-2512153|ensembl:ENSP00000363603.3|uniprotkb:Q14335|uniprotkb:Q8NAC2|uniprotkb:Q3LID0|uniprotkb:Q14334|uniprotkb:B2RBG3	intact:EBI-21285556	psi-mi:fuco_human(display_long)|uniprotkb:FUCA1(gene name)|psi-mi:FUCA1(display_short)|uniprotkb:Alpha-L-fucoside fucohydrolase 1(gene name synonym)|uniprotkb:Alpha-L-fucosidase I(gene name synonym)|uniprotkb:Nbla10230(orf name)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285676|imex:IM-26899-129	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000179163.12(gene)|ensembl:ENST00000374479.4(transcript)|go:""GO:0004560""(alpha-L-fucosidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0006004""(fucose metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016139""(glycoside catabolic process)|go:""GO:0019377""(glycolipid catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000933(""Glycoside hydrolase, family 29 (alpha-L-fucosidase)"")|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR016286(Alpha-L-fucosidase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018526|interpro:IPR031919|mint:P04066|rcsb pdb:7PLS|rcsb pdb:7PM4|reactome:R-HSA-6798695|reactome:R-HSA-975578|refseq:NP_000138.2|efo:""Orphanet:349""|panther:PTHR10030(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:hzGxBObvRAGMJxL+I9shJUo+nLg9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:0C7D17CD1BAFA840|rigid:T4JsdWxe1iahMlCZK/Pspfri+/0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NSE4	uniprotkb:Q83D60	intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889.2	intact:EBI-21285556	psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285700|imex:IM-26899-659	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:436174""|ensembl:ENSG00000067704.10(gene)|ensembl:ENST00000366922.3(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004822""(isoleucine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006418""(tRNA aminoacylation for protein translation)|go:""GO:0006428""(isoleucyl-tRNA aminoacylation)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|interpro:IPR050081|mint:Q9NSE4|reactome:R-HSA-379726|reactome:R-HSA-9837999|refseq:NP_060530.3|panther:PTHR42765(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:08096F9C6F3AD715|rigid:JaivoSuemMz+vo3ANQhZZ/e27nM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q86X45	uniprotkb:Q83D60	intact:EBI-9379658|uniprotkb:Q13648|uniprotkb:Q4G183|ensembl:ENSP00000429791.1|ensembl:ENSP00000484634.1	intact:EBI-21285556	psi-mi:daa11_human(display_long)|uniprotkb:DNAAF11(gene name)|psi-mi:DNAAF11(display_short)|uniprotkb:LRRC6(gene name synonym)|uniprotkb:LRTP(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 6(gene name synonym)|uniprotkb:Leucine-rich testis-specific protein(gene name synonym)|uniprotkb:Protein tilB homolog(gene name synonym)|uniprotkb:TSLRP(gene name synonym)|uniprotkb:Testis-specific leucine-rich repeat protein(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285724|imex:IM-26899-463	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:244""|ensembl:ENSG00000129295.10(gene)|ensembl:ENST00000519595.5(transcript)|ensembl:ENST00000620350.5(transcript)|go:""GO:0003341""(cilium movement)|go:""GO:0003351""(epithelial cilium movement involved in extracellular fluid movement)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0008584""(male gonad development)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0031514""(motile cilium)|go:""GO:0036158""(outer dynein arm assembly)|go:""GO:0036159""(inner dynein arm assembly)|go:""GO:0044458""(motile cilium assembly)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0060287""(epithelial cilium movement involved in determination of left/right asymmetry)|go:""GO:0061458""(reproductive system development)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0070286""(axonemal dynein complex assembly)|go:""GO:0090651""(apical cytoplasm)|go:""GO:0090660""(cerebrospinal fluid circulation)|go:""GO:0120229""(protein localization to motile cilium)|go:""GO:0120293""(dynein axonemal particle)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR007052(CS domain)|interpro:IPR032675|mint:Q86X45|refseq:NP_001308890.1|refseq:NP_001308891.1|refseq:NP_001308892.1|refseq:NP_001308893.1|refseq:NP_001308894.1|refseq:NP_001308895.1|refseq:NP_036604.2|panther:PTHR18849(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:+KWpDTd1pD7UAK4rVDo5We0inVw9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:56E6B3A684BF2414|rigid:pps4RPiD79F2yvOXBPrx+9q8cDs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P53990	uniprotkb:Q83D60	intact:EBI-945994|intact:EBI-4324656|uniprotkb:A8KAH5|uniprotkb:Q9BQ81|uniprotkb:Q9BWN2|uniprotkb:Q3SYM4|uniprotkb:J3QLU7	intact:EBI-21285556	psi-mi:ist1_human(display_long)|uniprotkb:IST1(gene name)|psi-mi:IST1(display_short)|uniprotkb:Putative MAPK-activating protein PM28(gene name synonym)|uniprotkb:KIAA0174(gene name synonym)|uniprotkb:Charged multivesicular body protein 8(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285718|imex:IM-26899-349	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055576.2|refseq:NP_001257904.1|refseq:NP_001257906.1|refseq:NP_001257905.1|refseq:NP_001257907.1|go:""GO:0000785""(chromatin)|go:""GO:0005576""(extracellular region)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0008104""(protein localization)|go:""GO:0015031""(protein transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030496""(midbody)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0048668""(collateral sprouting)|go:""GO:0048672""(positive regulation of collateral sprouting)|go:""GO:0051301""(cell division)|go:""GO:0061640""(cytoskeleton-dependent cytokinesis)|go:""GO:0061952""(midbody abscission)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090541""(MIT domain binding)|go:""GO:0090543""(Flemming body)|go:""GO:1904903""(ESCRT III complex disassembly)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|interpro:IPR042277|rcsb pdb:3FRR|rcsb pdb:3FRS|rcsb pdb:3JC1|rcsb pdb:4U7E|rcsb pdb:4U7I|rcsb pdb:4U7Y|rcsb pdb:4WZX|rcsb pdb:6E8G|rcsb pdb:6TZ4|rcsb pdb:6TZ5|rcsb pdb:6TZA|rcsb pdb:7S7J|rcsb pdb:8UC6|reactome:R-HSA-6798695|reactome:R-HSA-9668328|mint:P53990|dip:DIP-42546N|ensembl:ENST00000329908.12|ensembl:ENSP00000330408.8|ensembl:ENSG00000182149.21|ensembl:ENST00000378798.9|ensembl:ENSP00000368075.5|ensembl:ENST00000378799.11|ensembl:ENSP00000368076.6|ensembl:ENST00000535424.5|ensembl:ENSP00000438399.1|ensembl:ENST00000538850.5|ensembl:ENSP00000463711.1|ensembl:ENST00000541571.6|ensembl:ENSP00000455860.1|ensembl:ENST00000544564.5|ensembl:ENSP00000457844.1|ensembl:ENST00000606369.5|ensembl:ENSP00000475853.1|panther:PTHR12161(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:RbWwKZ+sftO2x3UkFz8zAxVi2CU9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:0486DFC5C5E90394|rigid:eqQASWaMPPyDWSmest4l7rFj5t4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96M11	uniprotkb:Q83D60	intact:EBI-720016|uniprotkb:Q96BX9|uniprotkb:B3KXI8|ensembl:ENSP00000348815.3|ensembl:ENSP00000414884.2|ensembl:ENSP00000436833.1	intact:EBI-21285556	psi-mi:hyls1_human(display_long)|uniprotkb:HYLS1(gene name)|psi-mi:HYLS1(display_short)|uniprotkb:HLS(gene name synonym)|uniprotkb:Hydrolethalus syndrome protein 1(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285694|imex:IM-26899-657	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2189""|efo:""Orphanet:475""|ensembl:ENSG00000198331.11(gene)|ensembl:ENST00000356438.7(transcript)|ensembl:ENST00000425380.7(transcript)|ensembl:ENST00000526028.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0060271""(cilium assembly)|go:""GO:0097730""(non-motile cilium)|interpro:IPR026227|interpro:IPR027918|interpro:IPR052319|mint:Q96M11|refseq:NP_001128265.1|refseq:NP_659451.1|refseq:XP_005271487.1|refseq:XP_006718840.1|refseq:XP_011540961.1|refseq:XP_016872809.1|refseq:XP_016872810.1|panther:PTHR34174(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:6qsYE/EnF7/lGKFARgoQtUurYrk9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:009150CA7F3563E8|rigid:8hbp7OMtsXAB+0CvPqaEqgqDVj8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P51955	uniprotkb:Q83D60	intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966.4	intact:EBI-21285556	psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285761|imex:IM-26899-25	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000117650.13(gene)|ensembl:ENST00000366999.9(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000922""(spindle pole)|go:""GO:0001824""(blastocyst development)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030496""(midbody)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046602""(regulation of mitotic centrosome separation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051299""(centrosome separation)|go:""GO:0051301""(cell division)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1903126""(negative regulation of centriole-centriole cohesion)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR051131|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|refseq:XP_005273204.1|efo:""Orphanet:791""|panther:PTHR43671(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:7iozc82+IF+sGyerzvp571Uc1RM9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:25CAA27394F1FA76|rigid:4Kk5vKrDWEcJ2aNoyeSS8nh5N6s	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6P1N2	uniprotkb:Q83D60	intact:EBI-21285736	intact:EBI-21285556	psi-mi:q6p1n2_human(display_long)|uniprotkb:MTIF2(gene name)|psi-mi:MTIF2(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285749|imex:IM-26899-241	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR053905|mint:Q6P1N2|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|refseq:NP_001005369.1|refseq:NP_002444.2|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR044145"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:1tWvOfEeLJfg31GeKiTLztjnehU9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:536935C63AD656DC|rigid:rAy/j8Q5yofJ+dX+Dhg/xzq5dGg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P01106	uniprotkb:Q83D60	intact:EBI-447544|intact:EBI-1058440|uniprotkb:P01107|uniprotkb:Q14026|ensembl:ENSP00000478887.2|uniprotkb:A8WFE7|uniprotkb:A0A024R9L7|uniprotkb:A0A087WUS5|uniprotkb:H0YBT0	intact:EBI-21285556	psi-mi:myc_human(display_long)|uniprotkb:BHLHE39(gene name synonym)|uniprotkb:Transcription factor p64(gene name synonym)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short)|uniprotkb:Proto-oncogene c-Myc(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 39(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285755|imex:IM-26899-755	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR45851(orthology-group)|ensembl:ENSG00000136997.22(gene)|ensembl:ENST00000621592.8(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001658""(branching involved in ureteric bud morphogenesis)|go:""GO:0002053""(positive regulation of mesenchymal cell proliferation)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006974""(DNA damage response)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010564""(regulation of cell cycle process)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016072""(rRNA metabolic process)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032873""(negative regulation of stress-activated MAPK cascade)|go:""GO:0032986""(protein-DNA complex disassembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044027""(negative regulation of gene expression via chromosomal CpG island methylation)|go:""GO:0044346""(fibroblast apoptotic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045656""(negative regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0051276""(chromosome organization)|go:""GO:0051782""(negative regulation of cell division)|go:""GO:0060633""(negative regulation of transcription initiation by RNA polymerase II)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070848""(response to growth factor)|go:""GO:0070888""(E-box binding)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071943""(Myc-Max complex)|go:""GO:0090096""(positive regulation of metanephric cap mesenchymal cell proliferation)|go:""GO:0090571""(RNA polymerase II transcription repressor complex)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:1902255""(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904672""(regulation of somatic stem cell population maintenance)|go:""GO:1905761""(SCF ubiquitin ligase complex binding)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|interpro:IPR050433|mint:P01106|rcsb pdb:1A93|rcsb pdb:1EE4|rcsb pdb:1MV0|rcsb pdb:1NKP|rcsb pdb:2A93|rcsb pdb:2OR9|rcsb pdb:4Y7R|rcsb pdb:5I4Z|rcsb pdb:5I50|rcsb pdb:6C4U|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|rcsb pdb:7T1Y|rcsb pdb:7T1Z|rcsb pdb:8J2Q|rcsb pdb:8OTS|rcsb pdb:8OTT|rcsb pdb:8Q1N|rcsb pdb:8WLG|rcsb pdb:8X8S|rcsb pdb:8X8V|reactome:R-HSA-1362277|reactome:R-HSA-201556|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-4411364|reactome:R-HSA-5687128|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8866911|reactome:R-HSA-8951430|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-9818749|refseq:NP_002458.2|efo:""Orphanet:480541""|efo:""Orphanet:543""|efo:""Orphanet:99861""|dip:DIP-28143N|ensembl:ENST00000377970.6|ensembl:ENSP00000367207.3|ensembl:ENST00000524013.2|ensembl:ENSP00000430235.2|ensembl:ENSP00000478887.2|ensembl:ENST00000652288.1|ensembl:ENSP00000499105.1|ensembl:ENST00000707113.1|ensembl:ENSP00000516742.1|ensembl:ENST00000707114.1|ensembl:ENSP00000516743.1|ensembl:ENST00000707115.1|ensembl:ENSP00000516744.1|ensembl:ENST00000707116.1|ensembl:ENSP00000516745.1"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/20	rogid:jNEC0lQUsHEP4yrhP/+BtWmCQc09606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:001EDD008817555C|rigid:L1Ab3jpiDlKNFPkUwtA9aj+iZlc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96GC5	uniprotkb:Q83D60	intact:EBI-5325315|uniprotkb:Q49AK7|uniprotkb:Q4U2Q4|uniprotkb:Q9P091|uniprotkb:Q9Y5J0|uniprotkb:B4DN34|intact:EBI-10967301|ensembl:ENSP00000308717.7	intact:EBI-21285556	psi-mi:rm48_human(display_long)|uniprotkb:MRPL48(gene name)|psi-mi:MRPL48(display_short)|uniprotkb:39S ribosomal protein L48, mitochondrial(gene name synonym)|uniprotkb:CGI-118(orf name)|uniprotkb:HSPC290(orf name)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285730|imex:IM-26899-663	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057139.1|refseq:NP_001305427.1|refseq:NP_001305428.1|refseq:NP_001305429.1|ensembl:ENSG00000175581.14(gene)|ensembl:ENST00000310614.12(transcript)|go:""GO:0005739""(mitochondrion)|mint:Q96GC5|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005761""(mitochondrial ribosome)|go:""GO:0005762""(mitochondrial large ribosomal subunit)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR027486|interpro:IPR027487|interpro:IPR036838|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:7OI7|rcsb pdb:7OI8|rcsb pdb:7OI9|rcsb pdb:7OIA|rcsb pdb:7OIB|rcsb pdb:7OIC|rcsb pdb:7OID|rcsb pdb:7OIE|rcsb pdb:7PD3|rcsb pdb:7PO4|rcsb pdb:7QH7|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8K2A|rcsb pdb:8K2B|rcsb pdb:8OIR|rcsb pdb:8OIT|rcsb pdb:8PK0|rcsb pdb:8QSJ|rcsb pdb:8QU5|rcsb pdb:8XT0|rcsb pdb:8XT1|rcsb pdb:8XT2|rcsb pdb:8XT3|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR13473(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:xCdGuctoVF3DrDHZedpDi+IOxxQ9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:CC893FBC0B70CF21|rigid:l4QxqotMAJinkEuou2uDWsoloeU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P18669	uniprotkb:Q83D60	intact:EBI-717905|uniprotkb:Q9BWC0|ensembl:ENSP00000359991.4	intact:EBI-21285556	psi-mi:pgam1_human(display_long)|uniprotkb:Phosphoglycerate mutase isozyme B(gene name synonym)|uniprotkb:BPG-dependent PGAM 1(gene name synonym)|uniprotkb:PGAM1(gene name)|psi-mi:PGAM1(display_short)|uniprotkb:CDABP0006(orf name)|uniprotkb:PGAMA(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285773|imex:IM-26899-351	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002620.1|ensembl:ENSG00000171314.9(gene)|ensembl:ENST00000334828.6(transcript)|go:""GO:0004082""(bisphosphoglycerate mutase activity)|go:""GO:0004619""(phosphoglycerate mutase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0016020""(membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0046538""(obsolete 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:P18669|rcsb pdb:1YFK|rcsb pdb:1YJX|rcsb pdb:4GPI|rcsb pdb:4GPZ|rcsb pdb:5Y2I|rcsb pdb:5Y2U|rcsb pdb:5Y35|rcsb pdb:5Y64|rcsb pdb:5Y65|rcsb pdb:5ZRM|rcsb pdb:5ZS8|rcsb pdb:6ISN|rcsb pdb:7XB7|rcsb pdb:7XB8|rcsb pdb:7XB9|rcsb pdb:8IT4|rcsb pdb:8IT5|rcsb pdb:8IT6|rcsb pdb:8IT7|rcsb pdb:8IT8|rcsb pdb:8ITB|rcsb pdb:8ITC|rcsb pdb:8ITD|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263|panther:PTHR11931(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:GI6jwRrX08owCyzx8KnRU8QP2rg9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:A20D8E689DF2AD7D|rigid:gk3GFq1Q5rHzmAMxs1b1M/d2+lk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q12857	uniprotkb:Q83D60	intact:EBI-2795262|uniprotkb:Q8TA97|uniprotkb:Q9H3X9|uniprotkb:Q9P2A9|uniprotkb:B4DRJ3|uniprotkb:B4DS53|uniprotkb:F5H0R0|uniprotkb:F8W8W3|ensembl:ENSP00000384523.3	intact:EBI-21285556	psi-mi:nfia_human(display_long)|uniprotkb:NFIA(gene name)|psi-mi:NFIA(display_short)|uniprotkb:KIAA1439(gene name synonym)|uniprotkb:Nuclear factor I/A(gene name synonym)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:TGGCA-binding protein(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285767|imex:IM-26899-567	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:401986""|ensembl:ENSG00000162599.18(gene)|ensembl:ENST00000403491.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0009611""(response to wounding)|go:""GO:0010458""(exit from mitosis)|go:""GO:0010467""(gene expression)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0019079""(viral genome replication)|go:""GO:0021780""(glial cell fate specification)|go:""GO:0030054""(cell junction)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0035108""(limb morphogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048665""(neuron fate specification)|go:""GO:0051216""(cartilage development)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0060074""(synapse maturation)|go:""GO:0061351""(neural precursor cell proliferation)|go:""GO:0072189""(ureter development)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR000647(CTF/NF-I)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR019548|interpro:IPR019739|interpro:IPR020604|mint:Q12857|reactome:R-HSA-73980|reactome:R-HSA-749476|refseq:NP_001128145.1|refseq:NP_001138983.1|refseq:NP_001138984.1|refseq:NP_005586.1|panther:PTHR11492(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:4NbJmVObdwd3x/axUAh/ESky6Yw9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:402B64A201A5D409|rigid:8gGm86m7PteL2sIjMg5v+CYuPOY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15181	uniprotkb:Q83D60	intact:EBI-712298|uniprotkb:Q2M348|uniprotkb:Q5SQT7|uniprotkb:Q6P7P4|uniprotkb:Q9UQJ5|uniprotkb:Q9Y5B1|ensembl:ENSP00000362329.2	intact:EBI-21285556	psi-mi:ipyr_human(display_long)|uniprotkb:Pyrophosphate phospho-hydrolase(gene name synonym)|uniprotkb:PPA1(gene name)|psi-mi:PPA1(display_short)|uniprotkb:IOPPP(gene name synonym)|uniprotkb:PP(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285797|imex:IM-26899-665	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066952.1|ensembl:ENSG00000180817.12(gene)|ensembl:ENST00000373232.8(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004427""(inorganic diphosphate phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006796""(phosphate-containing compound metabolic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q15181|rcsb pdb:6C45|rcsb pdb:7BTN|rcsb pdb:7CMO|rcsb pdb:8J7Q|reactome:R-HSA-379716|reactome:R-HSA-71737|panther:PTHR10286(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:1094gn9aeisgfDUhIroRn2iqom49606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:A33BE1100FEAA39B|rigid:M6EgQ2oJYwwvK82GNwBY+QTAZp0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O00469	uniprotkb:Q83D60	intact:EBI-1047459|uniprotkb:Q59ED2|uniprotkb:Q8N170|intact:EBI-2559757|ensembl:ENSP00000353170.3|ensembl:ENSP00000515354.1|uniprotkb:B3KWS3	intact:EBI-21285556	psi-mi:plod2_human(display_long)|uniprotkb:Lysyl hydroxylase 2(gene name synonym)|uniprotkb:PLOD2(gene name)|psi-mi:PLOD2(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285785|imex:IM-26899-353	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000152952.14(gene)|ensembl:ENST00000360060.7(transcript)|ensembl:ENST00000703523.1(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0005506""(iron ion binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0008475""(procollagen-lysine 5-dioxygenase activity)|go:""GO:0017185""(peptidyl-lysine hydroxylation)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030867""(rough endoplasmic reticulum membrane)|go:""GO:0031418""(L-ascorbic acid binding)|go:""GO:0036211""(protein modification process)|go:""GO:0046947""(hydroxylysine biosynthetic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123(""2OG-Fe(II) oxygenase"")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|interpro:IPR044861|interpro:IPR050757|mint:O00469|reactome:R-HSA-1650814|refseq:NP_000926.2|refseq:NP_891988.1|efo:""Orphanet:2771""|panther:PTHR10730(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:sNgFtZzNoKBCz7KUhTBfMG/xxas9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:22E033A571191257|rigid:L0f/mUh/8UKd58zRdHFTUhc0prc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P54277	uniprotkb:Q83D60	intact:EBI-2893308|uniprotkb:D3DPI1|uniprotkb:Q4VAL4|uniprotkb:Q5FBZ8|uniprotkb:Q5FBZ3|uniprotkb:Q5FBZ6|ensembl:ENSP00000406490.3	intact:EBI-21285556	psi-mi:pms1_human(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:PMSL1(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS1(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285791|imex:IM-26899-133	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000064933.19(gene)|ensembl:ENST00000441310.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0006298""(mismatch repair)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030983""(mismatched DNA binding)|go:""GO:0032389""(MutLalpha complex)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR036890|interpro:IPR036910|interpro:IPR038973|mint:P54277|rcsb pdb:2CS1|refseq:NP_000525.1|refseq:NP_001121615.1|refseq:NP_001121616.1|refseq:NP_001276337.1|refseq:NP_001307974.1|refseq:NP_001307975.1|refseq:NP_001307976.1|refseq:NP_001307977.1|refseq:XP_016859833.1|refseq:XP_016859837.1|efo:""Orphanet:144""|panther:PTHR10073(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:URnCj+2/Inh5Wsc1UFHYh1gowFQ9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:A28F9718AB059831|rigid:SRUUDuspvdZQdiC6hEi0tsK9OiM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5JRX3	uniprotkb:Q83D60	intact:EBI-2432778|uniprotkb:B4E0J8|uniprotkb:E7ES23|uniprotkb:B3KMJ6|uniprotkb:O95204|uniprotkb:Q2M2G6|uniprotkb:Q4VBR1|uniprotkb:Q5JRW7|uniprotkb:Q7L5Z7|uniprotkb:Q9BSI6|uniprotkb:Q9BVJ5|uniprotkb:Q9UPP8|uniprotkb:C9JSL2|ensembl:ENSP00000224949.4	intact:EBI-21285556	psi-mi:prep_human(display_long)|uniprotkb:PITRM1(gene name)|psi-mi:PITRM1(display_short)|uniprotkb:KIAA1104(gene name synonym)|uniprotkb:MP1(gene name synonym)|uniprotkb:Pitrilysin metalloproteinase 1(gene name synonym)|uniprotkb:PREP(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285779|imex:IM-26899-27	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229236.1|refseq:NP_001229238.1|refseq:NP_055704.2|ensembl:ENSG00000107959.17(gene)|ensembl:ENST00000224949.9(transcript)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006508""(proteolysis)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016485""(protein processing)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR013578(Peptidase M16C associated)|interpro:IPR055130|mint:Q5JRX3|rcsb pdb:4L3T|rcsb pdb:4NGE|rcsb pdb:4RPU|rcsb pdb:6XOS|rcsb pdb:6XOT|rcsb pdb:6XOU|rcsb pdb:6XOV|rcsb pdb:6XOW|reactome:R-HSA-1268020|dip:DIP-52900N|panther:PTHR43016(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:1kEY/XJB5fwgNRoM9u9ZGT+VrS09606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:F11F4536B9D54014|rigid:DFGF+X6QcG/CnhozoDIq70n0zhE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96HL8	uniprotkb:Q83D60	intact:EBI-722667|uniprotkb:B7WPL6|intact:EBI-749123|uniprotkb:A8K8E7|uniprotkb:Q9H5X4|uniprotkb:Q9Y3V5|uniprotkb:Q8NEL2|uniprotkb:B7WNJ4|ensembl:ENSP00000348471.5|ensembl:ENSP00000384269.1|intact:EBI-28983457	intact:EBI-21285556	psi-mi:sh3y1_human(display_long)|uniprotkb:SH3YL1(gene name)|psi-mi:SH3YL1(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285833|imex:IM-26899-355	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001153069.1|refseq:NP_001269611.1|refseq:NP_001269616.1|refseq:NP_056492.2|ensembl:ENSG00000035115.22(gene)|ensembl:ENST00000356150.10(transcript)|ensembl:ENST00000405430.5(transcript)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:1900027""(regulation of ruffle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR035511|interpro:IPR036028|interpro:IPR051702|mint:Q96HL8|rcsb pdb:2D8H|panther:PTHR15629(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:xet0gjUb2Hgt8wCxwQyMs2AYmig9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:6B2172B5CCAFD6D0|rigid:/5ucmPKKful3gjzVtVn6P1YdBvo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UNP9	uniprotkb:Q83D60	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769.5	intact:EBI-21285556	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285803|imex:IM-26899-243	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006103.1|refseq:NP_001181936.1|ensembl:ENSG00000084072.17(gene)|ensembl:ENST00000324379.10(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006457""(protein folding)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0016018""(cyclosporin A binding)|go:""GO:0016607""(nuclear speck)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:7ZEV|rcsb pdb:7ZEW|rcsb pdb:7ZEX|rcsb pdb:7ZEY|rcsb pdb:7ZEZ|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:9FMD|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163|refseq:NP_982281.1|refseq:XP_016855540.1|dip:DIP-34757N"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/21	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:BA73912F435FAEA2|rigid:Ys7GfTvJwmBH8iSN/2XhiHKXDjk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P62241	uniprotkb:Q83D60	intact:EBI-351811|uniprotkb:Q6IRL7|uniprotkb:P09058|ensembl:ENSP00000379888.3	intact:EBI-21285556	psi-mi:rs8_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short)|uniprotkb:40S ribosomal protein S8(gene name synonym)|uniprotkb:OK/SW-cl.83(orf name)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285827|imex:IM-26899-671	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001003.1|ensembl:ENSG00000142937.12(gene)|ensembl:ENST00000396651.8(transcript)|go:""GO:0000462""(""maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0016020""(membrane)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0032040""(small-subunit processome)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:P62241|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7QVP|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7WTS|rcsb pdb:7WTT|rcsb pdb:7WTU|rcsb pdb:7WTV|rcsb pdb:7WTW|rcsb pdb:7WTX|rcsb pdb:7WTZ|rcsb pdb:7WU0|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9735869|reactome:R-HSA-9754678|reactome:R-HSA-975956|reactome:R-HSA-975957|panther:PTHR10394(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:3rpCBdQyRWR+TCKnupbnCp30jKE9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:4C3B158F2882D89A|rigid:fGOWwgb/IxAapbECVrbiMVW7pOE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14671	uniprotkb:Q83D60	intact:EBI-948453|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3|ensembl:ENSP00000257075.5	intact:EBI-21285556	psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285815|imex:IM-26899-667	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-29082N|efo:""Orphanet:589515""|efo:""Orphanet:642747""|ensembl:ENSG00000134644.16(gene)|ensembl:ENST00000257075.9(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006417""(regulation of translation)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016441""(post-transcriptional gene silencing)|go:""GO:0030424""(axon)|go:""GO:0035196""(miRNA processing)|go:""GO:0035198""(miRNA binding)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0048863""(stem cell differentiation)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051983""(regulation of chromosome segregation)|go:""GO:0060964""(regulation of miRNA-mediated gene silencing)|go:""GO:0061157""(mRNA destabilization)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:1900246""(positive regulation of RIG-I signaling pathway)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|refseq:NP_001018494.1|refseq:NP_055491.1|panther:PTHR12537(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/28	rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:6CFB00B2203478D9|rigid:CuB1xthZtaiZAVDvZtWJcAkJ9t8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14157	uniprotkb:Q83D60	intact:EBI-347762|ensembl:ENSP00000355343.2|ensembl:ENSP00000389445.1|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4	intact:EBI-21285556	psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym)|uniprotkb:RNA polymerase II degradation factor UBAP2L(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285893|imex:IM-26899-359	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143569.20(gene)|ensembl:ENST00000361546.6(transcript)|ensembl:ENST00000428931.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0031519""(PcG protein complex)|go:""GO:0034063""(stress granule assembly)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|go:""GO:0062029""(positive regulation of stress granule assembly)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|interpro:IPR051833|mint:Q14157|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_011508518.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|panther:PTHR16308(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:E8FBD23BEBF10A52|rigid:314Fv6TjrWvv/afKL9QU7GHJz3c	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8IYM9	uniprotkb:Q83D60	intact:EBI-954123|uniprotkb:Q15521|uniprotkb:Q05CQ0|ensembl:ENSP00000369299.3	intact:EBI-21285556	psi-mi:tri22_human(display_long)|uniprotkb:RING finger protein 94(gene name synonym)|uniprotkb:50 kDa-stimulated trans-acting factor(gene name synonym)|uniprotkb:Staf-50(gene name synonym)|uniprotkb:Tripartite motif-containing protein 22(gene name synonym)|uniprotkb:TRIM22(gene name)|psi-mi:TRIM22(display_short)|uniprotkb:RNF94(gene name synonym)|uniprotkb:STAF50(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM22(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285887|imex:IM-26899-137	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001186502.1|refseq:NP_006065.2|ensembl:ENSG00000132274.17(gene)|ensembl:ENST00000379965.8(transcript)|go:""GO:0002230""(positive regulation of defense response to virus by host)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006955""(immune response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009615""(response to virus)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0015030""(Cajal body)|go:""GO:0016604""(nuclear body)|go:""GO:0016607""(nuclear speck)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045087""(innate immune response)|go:""GO:0046596""(regulation of viral entry into host cell)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051607""(defense response to virus)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR035827|interpro:IPR043136|interpro:IPR050143|mint:Q8IYM9|reactome:R-HSA-877300|panther:PTHR24103(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:8CNTleevg3ll6+eu/3p28ysv1M09606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:16D6FC4F3F88A684|rigid:Vq/dJV32mwNW06U89e/H8cOiXgg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15431	uniprotkb:Q83D60	intact:EBI-2555298|uniprotkb:Q5VXJ6|uniprotkb:O14963|ensembl:ENSP00000358531.1|ensembl:ENSP00000358535.3|ensembl:ENSP00000480997.1	intact:EBI-21285556	psi-mi:sycp1_human(display_long)|uniprotkb:SCP1(gene name synonym)|uniprotkb:Cancer/testis antigen 8(gene name synonym)|uniprotkb:SYCP1(gene name)|psi-mi:SYCP1(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285869|imex:IM-26899-757	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003167.2|refseq:NP_001269470.1|refseq:XP_006710922.1|refseq:XP_016857673.1|ensembl:ENSG00000198765.12(gene)|ensembl:ENST00000369518.1(transcript)|ensembl:ENST00000369522.8(transcript)|ensembl:ENST00000618516.4(transcript)|go:""GO:0000711""(meiotic DNA repair synthesis)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000795""(synaptonemal complex)|go:""GO:0000801""(central element)|go:""GO:0000802""(transverse filament)|go:""GO:0001673""(male germ cell nucleus)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005694""(chromosome)|go:""GO:0007129""(homologous chromosome pairing at meiosis)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007131""(reciprocal meiotic recombination)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030849""(autosome)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0035092""(sperm DNA condensation)|go:""GO:0051026""(chiasma assembly)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0051301""(cell division)|go:""GO:0051878""(lateral element assembly)|interpro:IPR008827(Synaptonemal complex 1)|mint:Q15431|rcsb pdb:4YTO|rcsb pdb:6F5X|rcsb pdb:6F62|rcsb pdb:6F63|rcsb pdb:6F64|reactome:R-HSA-1221632|panther:PTHR46918(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:jvR0EZ6l7soQDldrQCBEbGcueB89606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:AB5BD4D26119FE6E|rigid:pkA1rTnae9liyKAcRd8nTiVx2sc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P49746	uniprotkb:Q83D60	intact:EBI-2530931|uniprotkb:B1AVR8|uniprotkb:Q8WV34|ensembl:ENSP00000357362.3|uniprotkb:B4DQ20	intact:EBI-21285556	psi-mi:tsp3_human(display_long)|uniprotkb:THBS3(gene name)|psi-mi:THBS3(display_short)|uniprotkb:TSP3(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285875|imex:IM-26899-571	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009043.1|refseq:NP_001239536.1|refseq:NP_001239537.1|ensembl:ENSG00000169231.13(gene)|ensembl:ENST00000368378.7(transcript)|go:""GO:0003417""(growth plate cartilage development)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0060346""(bone trabecula formation)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017897|interpro:IPR018097|interpro:IPR024665|interpro:IPR028507|interpro:IPR028974|interpro:IPR046970|interpro:IPR048287|interpro:IPR049883|mint:P49746|reactome:R-HSA-186797|panther:PTHR10199(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:v41BoGII7o5DU7gHTLSm328R+9w9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:62235193A9B451F3|rigid:Az31C67DUmUBiNtXKBxNcqH2JKE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q92547	uniprotkb:Q83D60	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810.5	intact:EBI-21285556	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285881|imex:IM-26899-465	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_008958.2|ensembl:ENSG00000163781.14(gene)|ensembl:ENST00000260810.10(transcript)|go:""GO:0000076""(DNA replication checkpoint signaling)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000922""(spindle pole)|go:""GO:0001673""(male germ cell nucleus)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006259""(DNA metabolic process)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006281""(DNA repair)|go:""GO:0006974""(DNA damage response)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0010212""(response to ionizing radiation)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016604""(nuclear body)|go:""GO:0016605""(PML body)|go:""GO:0033314""(mitotic DNA replication checkpoint signaling)|go:""GO:0035825""(homologous recombination)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042802""(identical protein binding)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0051276""(chromosome organization)|go:""GO:0070532""(BRCA1-B complex)|go:""GO:0090734""(site of DNA damage)|go:""GO:0097680""(double-strand break repair via classical nonhomologous end joining)|go:""GO:0097681""(double-strand break repair via alternative nonhomologous end joining)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140463""(chromatin-protein adaptor activity)|go:""GO:0141112""(broken chromosome clustering)|go:""GO:1990166""(protein localization to site of double-strand break)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|interpro:IPR049542|interpro:IPR049936|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9709570|refseq:XP_016861125.1|dip:DIP-24263N|panther:PTHR13561(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:E19475C07FDF7A6F|rigid:wlEgMLqbmRnZqB7UQK6khm4gbmo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TCU3	uniprotkb:Q83D60	intact:EBI-21285839|ensembl:ENSP00000297524.3|uniprotkb:Q05C37|uniprotkb:Q08AH9|uniprotkb:Q96N84	intact:EBI-21285556	psi-mi:s7a13_human(display_long)|uniprotkb:SLC7A13(gene name)|psi-mi:SLC7A13(display_short)|uniprotkb:AGT1(gene name synonym)|uniprotkb:XAT2(gene name synonym)|uniprotkb:Sodium-independent aspartate/glutamate transporter 1(gene name synonym)|uniprotkb:X-amino acid transporter 2(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285857|imex:IM-26899-357	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164893.9(gene)|ensembl:ENST00000297524.8(transcript)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015810""(aspartate transmembrane transport)|go:""GO:0015811""(L-cystine transport)|go:""GO:0015813""(L-glutamate transmembrane transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0046982""(protein heterodimerization activity)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR050598|mint:Q8TCU3|refseq:NP_620172.2|panther:PTHR11785(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:W8HPrBO1TnsueOONPohwDYH1z9c9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:E265B75CF64FC18C|rigid:6rq0Axz9Ukd0YVUIYvoIyUiulYM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P20618	uniprotkb:Q83D60	intact:EBI-372273|ensembl:ENSP00000262193.6|uniprotkb:Q9BWA8|uniprotkb:B5BU76	intact:EBI-21285556	psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym)|uniprotkb:Proteasome subunit beta-6(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285809|imex:IM-26899-135	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000008018.9(gene)|ensembl:ENST00000262193.7(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019774""(proteasome core complex, beta-subunit complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|panther:PTHR32194(orthology-group)|refseq:NP_002784.1|dip:DIP-31193N"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/05	rogid:DfIS480BUnqbXus9/KoojdkWgw09606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:6A9E3917FE29EB42|rigid:OvG/fPP+B8r0IGfELYMtMxM1R6A	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8NHS9	uniprotkb:Q83D60	intact:EBI-7067260|ensembl:ENSP00000380354.3|ensembl:ENSP00000459329.1|ensembl:ENSP00000459580.1|ensembl:ENSP00000460187.1|intact:MINT-8201601|uniprotkb:D3DTI9|uniprotkb:J3KN63|uniprotkb:Q96JT4|uniprotkb:Q969H3|uniprotkb:B4DXB1	intact:EBI-21285556	psi-mi:spt22_human(display_long)|uniprotkb:SPATA22(gene name)|psi-mi:SPATA22(display_short)|uniprotkb:Testis development protein NYD-SP20(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285863|imex:IM-26899-569	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000141255.13(gene)|ensembl:ENST00000397168.7(transcript)|ensembl:ENST00000572969.6(transcript)|ensembl:ENST00000573128.5(transcript)|ensembl:ENST00000575375.5(transcript)|go:""GO:0000711""(meiotic DNA repair synthesis)|go:""GO:0005694""(chromosome)|go:""GO:0007129""(homologous chromosome pairing at meiosis)|go:""GO:0009566""(fertilization)|go:""GO:0048137""(spermatocyte division)|go:""GO:0051445""(regulation of meiotic cell cycle)|go:""GO:0061458""(reproductive system development)|interpro:IPR033536|mint:Q8NHS9|refseq:NP_001164167.1|refseq:NP_001164169.1|refseq:NP_115987.2|refseq:NP_001164168.1|refseq:NP_001164166.1|refseq:NP_001164170.1|refseq:NP_001308265.1|refseq:NP_001308266.1|panther:PTHR35258(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	comment:mint|comment:homomint	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:6SGHXJywVk383ITHBKxLAhAfXuE9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:D02E6C01D8246059|rigid:a7X7uM+Q9RHwA4LqeZOYk7pxKi8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P49802	uniprotkb:Q83D60	intact:EBI-1754797|uniprotkb:Q8TD66|uniprotkb:Q8TD67|uniprotkb:Q9UNU7|uniprotkb:Q9Y6B9|uniprotkb:Q5T3H4|uniprotkb:Q8WW09|ensembl:ENSP00000404399.2	intact:EBI-21285556	psi-mi:rgs7_human(display_long)|uniprotkb:RGS7(gene name)|psi-mi:RGS7(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285821|imex:IM-26899-669	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269702.1|refseq:NP_001269704.1|refseq:NP_001269707.1|refseq:NP_002915.3|ensembl:ENSG00000182901.18(gene)|ensembl:ENST00000440928.6(transcript)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0031681""(G-protein beta-subunit binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0043005""(neuron projection)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045471""(response to ethanol)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:1901381""(positive regulation of potassium ion transmembrane transport)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036284|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|interpro:IPR040759|interpro:IPR044926|interpro:IPR047016|interpro:IPR047017|mint:P49802|rcsb pdb:2A72|rcsb pdb:2D9J|rcsb pdb:7EWP|rcsb pdb:7EWR|rcsb pdb:7SHF|reactome:R-HSA-418594|reactome:R-HSA-6814122|refseq:XP_005273275.1|dip:DIP-40869N|panther:PTHR45746(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:epeNPVu00d27S9hlaKto1/bKwhI9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:135C6285D764322F|rigid:HBFX7OQnp4clvuCTuIcXYrvP/tA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NZV7	uniprotkb:Q83D60	intact:EBI-11962760|uniprotkb:Q2M3K1|ensembl:ENSP00000468984.1|ensembl:ENSP00000470326.1|ensembl:ENSP00000472306.1	intact:EBI-21285556	psi-mi:zim2_human(display_long)|uniprotkb:ZIM2(gene name)|psi-mi:ZIM2(display_short)|uniprotkb:ZNF656(gene name synonym)|uniprotkb:Zinc finger protein 656(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285911|imex:IM-26899-673	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001139798.1|refseq:NP_001139799.1|refseq:NP_056178.3|ensembl:ENSG00000269699.8(gene)|ensembl:ENST00000593711.6(transcript)|ensembl:ENST00000599935.5(transcript)|ensembl:ENST00000601070.5(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q9NZV7|reactome:R-HSA-212436|panther:PTHR23232(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:m5QQuE7S1ZDsqhxEzm9Z1z80i089606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:FC2536A6263D7DDD|rigid:46arGFwUjOYd6bZZufX7Z2twebo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBW7	uniprotkb:Q83D60	intact:EBI-2797576|ensembl:ENSP00000372324.2|ensembl:ENSP00000372327.2|ensembl:ENSP00000479904.1|intact:EBI-25598824|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898	intact:EBI-21285556	psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285917|imex:IM-26899-675	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000121741.17(gene)|ensembl:ENST00000382871.3(transcript)|ensembl:ENST00000382874.6(transcript)|ensembl:ENST00000610343.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016605""(PML body)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|interpro:IPR051284|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|refseq:XP_005266577.1|refseq:XP_011533526.1|refseq:XP_016876218.1|efo:""Orphanet:528084""|panther:PTHR45736(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:0C18929B7CD3F8F2|rigid:V1C2fEBWAyD9nhn6UKIoHHd5YVU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9GZX5	uniprotkb:Q83D60	intact:EBI-396421|uniprotkb:Q9HAQ4|uniprotkb:Q96G73|ensembl:ENSP00000243644.3	intact:EBI-21285556	psi-mi:zn350_human(display_long)|uniprotkb:Zinc finger protein ZBRK1(gene name synonym)|uniprotkb:Zinc finger and BRCA1-interacting protein with a KRAB domain 1(gene name synonym)|uniprotkb:KRAB zinc finger protein ZFQR(gene name synonym)|uniprotkb:ZNF350(gene name)|psi-mi:ZNF350(display_short)|uniprotkb:ZBRK1(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285929|imex:IM-26899-29	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067645.3|ensembl:ENSG00000256683.7(gene)|ensembl:ENST00000243644.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001162""(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016604""(nuclear body)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR050527|mint:Q9GZX5|reactome:R-HSA-212436|reactome:R-HSA-3899300|refseq:XP_016882587.1|refseq:XP_016882588.1|refseq:XP_016882589.1|panther:PTHR24404(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:n3L44uqErawnnBhZCDI2B7hnZxQ9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:58EBFDAC3EEECD2F|rigid:LZqHk4sRw42KCtphLSMo6D+2tCs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q03188	uniprotkb:Q83D57	intact:EBI-295799|uniprotkb:Q9P0M5|ensembl:ENSP00000273853.6|uniprotkb:Q8IW27|uniprotkb:Q6PIR0	intact:EBI-21285947	psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym)	psi-mi:q83d57_coxbu(display_long)|uniprotkb:CBU_0885(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285953|imex:IM-26899-139	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001803.2|ensembl:ENSG00000145241.11(gene)|ensembl:ENST00000273853.11(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0000779""(condensed chromosome, centromeric region)|go:""GO:0000939""(inner kinetochore)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005829""(cytosol)|go:""GO:0007059""(chromosome segregation)|go:""GO:0016604""(nuclear body)|go:""GO:0019237""(centromeric DNA binding)|go:""GO:0030496""(midbody)|go:""GO:0042802""(identical protein binding)|go:""GO:0051301""(cell division)|go:""GO:0051315""(attachment of mitotic spindle microtubules to kinetochore)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0051455""(spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:7PII|rcsb pdb:7QOO|rcsb pdb:7R5R|rcsb pdb:7XHN|rcsb pdb:7XHO|rcsb pdb:7YWX|rcsb pdb:7YYH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|panther:PTHR16684(orthology-group)"	mint:Q83D57|refseq:NP_819902.2|refseq:WP_010957867.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606	rogid:nmEtkvTQxaroeu4VK6t674RWCg0227377	intact-crc:C09FB5CDEE7E5494|rigid:RrBuDFSn1nyDQ12uYRZLns1Obmc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6P1N2	uniprotkb:Q83D60	intact:EBI-21285736	intact:EBI-21285556	psi-mi:q6p1n2_human(display_long)|uniprotkb:MTIF2(gene name)|psi-mi:MTIF2(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285941|imex:IM-26899-363	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR053905|mint:Q6P1N2|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|refseq:NP_001005369.1|refseq:NP_002444.2|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR044145"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:1tWvOfEeLJfg31GeKiTLztjnehU9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:536935C63AD656DC|rigid:rAy/j8Q5yofJ+dX+Dhg/xzq5dGg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9P1Z0	uniprotkb:Q83D60	intact:EBI-2564133|uniprotkb:B3KVL6|uniprotkb:Q7Z697|uniprotkb:Q86XJ4|uniprotkb:Q8N4V8|ensembl:ENSP00000307858.4|ensembl:ENSP00000369973.4|ensembl:ENSP00000492232.1|ensembl:ENSP00000492616.1	intact:EBI-21285556	psi-mi:zbtb4_human(display_long)|uniprotkb:ZBTB4(gene name)|psi-mi:ZBTB4(display_short)|uniprotkb:KIAA1538(gene name synonym)|uniprotkb:KAISO-like zinc finger protein 1(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285905|imex:IM-26899-759	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011522274.1|refseq:NP_001122305.1|refseq:NP_065950.2|ensembl:ENSG00000174282.12(gene)|ensembl:ENSG00000283868.2(gene)|ensembl:ENST00000311403.4(transcript)|ensembl:ENST00000380599.9(transcript)|ensembl:ENST00000639670.2(transcript)|ensembl:ENST00000639962.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006974""(DNA damage response)|go:""GO:0008327""(methyl-CpG binding)|go:""GO:0010428""(methyl-CpNpG binding)|go:""GO:0016604""(nuclear body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9P1Z0|refseq:XP_006721626.1|refseq:XP_006721627.1|panther:PTHR24388(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:CZJEikI46aYaPyxTb/FJnxTD5eM9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:E377716ECEC673C7|rigid:uMyEF4PrdCoItnK9/vnoDqCXt3Q	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P40818	uniprotkb:Q83D60	intact:EBI-1050865|uniprotkb:Q2TB31|uniprotkb:Q7Z3U2|uniprotkb:Q86VA0|uniprotkb:Q8IWI7|uniprotkb:B4DKA8|ensembl:ENSP00000302239.4|ensembl:ENSP00000379721.3	intact:EBI-21285556	psi-mi:ubp8_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:USP8(gene name)|psi-mi:USP8(display_short)|uniprotkb:KIAA0055(gene name synonym)|uniprotkb:UBPY(gene name synonym)|uniprotkb:Ubiquitin isopeptidase Y(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285899|imex:IM-26899-361	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-40365N|ensembl:ENSG00000138592.14(gene)|ensembl:ENST00000307179.9(transcript)|ensembl:ENST00000396444.7(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007032""(endosome organization)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0010008""(endosome membrane)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030496""(midbody)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0043197""(dendritic spine)|go:""GO:0045296""(cadherin binding)|go:""GO:0061578""(K63-linked deubiquitinase activity)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099576""(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:""GO:1905166""(negative regulation of lysosomal protein catabolic process)|go:""GO:1905908""(positive regulation of amyloid fibril formation)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990380""(K48-linked deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|interpro:IPR048498|interpro:IPR050185|mint:P40818|rcsb pdb:1WHB|rcsb pdb:2A9U|rcsb pdb:2GFO|rcsb pdb:2GWF|rcsb pdb:3N3K|rcsb pdb:6F09|rcsb pdb:8ADM|rcsb pdb:8XPN|rcsb pdb:8Y9A|reactome:R-HSA-1358803|reactome:R-HSA-4641263|reactome:R-HSA-5689880|reactome:R-HSA-6807004|refseq:NP_001122082.1|refseq:NP_001269978.1|refseq:NP_005145.3|refseq:XP_006720824.1|refseq:XP_011520495.1|efo:""Orphanet:401795""|efo:""Orphanet:96253""|panther:PTHR21646(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/27	rogid:hpBBzyA4lc9is80ZFJBr1fyEyOM9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:3014DD964728937A|rigid:0Vs8kxSd2CKY+5GX/Y2v4KJnDBc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7Z4V0	uniprotkb:Q83D60	intact:EBI-11962468|uniprotkb:A2A3J4|uniprotkb:A8K9L5|uniprotkb:Q5T426|uniprotkb:Q658Q4|uniprotkb:Q6ZN65|ensembl:ENSP00000354663.3|ensembl:ENSP00000387546.1|ensembl:ENSP00000406934.2|ensembl:ENSP00000412363.1	intact:EBI-21285556	psi-mi:zn438_human(display_long)|uniprotkb:ZNF438(gene name)|psi-mi:ZNF438(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285935|imex:IM-26899-245	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137238.1|refseq:NP_001137239.1|refseq:NP_001137240.1|refseq:NP_001137241.1|refseq:NP_001137242.1|refseq:NP_001137243.1|refseq:NP_877432.1|refseq:XP_006717456.1|refseq:XP_006717459.1|refseq:XP_006717461.1|refseq:XP_006717462.1|refseq:XP_011517673.1|refseq:XP_011517674.1|refseq:XP_011517675.1|refseq:XP_011517676.1|refseq:XP_011517678.1|refseq:XP_011517679.1|refseq:XP_016871353.1|refseq:XP_016871354.1|refseq:XP_016871355.1|refseq:XP_016871356.1|refseq:XP_016871357.1|refseq:XP_016871358.1|refseq:XP_016871359.1|refseq:XP_016871360.1|refseq:XP_016871361.1|refseq:XP_016871362.1|refseq:XP_016871363.1|ensembl:ENSG00000183621.15(gene)|ensembl:ENST00000361310.7(transcript)|ensembl:ENST00000413025.5(transcript)|ensembl:ENST00000436087.7(transcript)|ensembl:ENST00000442986.5(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z4V0|panther:PTHR24408(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:QreFTL8bKUgoRzL37basyvBZTSk9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:893056CE6E57B292|rigid:S5dMrzqIKsTeOTjxPkyE0WN7w6E	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13360	uniprotkb:Q83D60	intact:EBI-3921570|uniprotkb:Q96ER2|uniprotkb:B4DY57|uniprotkb:I3L0I4|uniprotkb:E9PDG0|ensembl:ENSP00000468531.1|ensembl:ENSP00000507083.1	intact:EBI-21285556	psi-mi:zn177_human(display_long)|uniprotkb:ZNF177(gene name)|psi-mi:ZNF177(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285923|imex:IM-26899-677	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001166121.1|refseq:NP_003442.2|refseq:NP_001189354.1|refseq:NP_001166122.1|ensembl:ENSG00000188629.14(gene)|ensembl:ENST00000589262.5(transcript)|ensembl:ENST00000683217.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0072562""(blood microparticle)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR050752|mint:Q13360|panther:PTHR24381(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:AQY71Gzch2ezw8lEB06fROw3QjM9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:1675E3E4776C05EC|rigid:zS+rsNK8Q63/Uyej29KEtvI/dro	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P20810	uniprotkb:Q83D09	intact:EBI-1268770|uniprotkb:G5E9D3|uniprotkb:O95360|uniprotkb:Q96D08|uniprotkb:Q9H1Z5|uniprotkb:Q7Z4K0|uniprotkb:Q05DE8|uniprotkb:G5E946|intact:EBI-11042429|uniprotkb:B7Z468	intact:EBI-21285965	psi-mi:ical_human(display_long)|uniprotkb:CAST(gene name)|psi-mi:CAST(display_short)|uniprotkb:Calpain inhibitor(gene name synonym)|uniprotkb:Sperm BS-17 component(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286001|imex:IM-26899-761	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003723""(RNA binding)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0010859""(calcium-dependent cysteine-type endopeptidase inhibitor activity)|go:""GO:0016020""(membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0097340""(obsolete inhibition of cysteine-type endopeptidase activity)|go:""GO:1990709""(presynaptic active zone organization)|go:""GO:2000675""(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR001259(Proteinase inhibitor I27, calpastatin)|interpro:IPR026998|mint:P20810|reactome:R-HSA-1474228|reactome:R-HSA-8862803|refseq:NP_001035905.1|refseq:NP_001035906.1|refseq:NP_001035907.1|refseq:NP_001035908.1|refseq:NP_001035909.1|refseq:NP_001271141.1|refseq:NP_001317560.1|refseq:NP_001741.4|refseq:NP_775083.1|refseq:XP_006714759.1|refseq:XP_006714764.1|refseq:XP_006714766.1|refseq:XP_006714767.1|refseq:XP_016865402.1|efo:""Orphanet:444138""|panther:PTHR10077(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:sDc8/o13gLhr18fYsz/grYg13Lo9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:E4F3B5388CA6B349|rigid:9tdBSrqJW1FSM3w4OpfYVWphAxc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00325	uniprotkb:Q83D09	intact:EBI-2838677|uniprotkb:Q4ZGI9|uniprotkb:Q13711|uniprotkb:Q96KI7|ensembl:ENSP00000306606.8|uniprotkb:A8MYN5|uniprotkb:B4DRS9|uniprotkb:B4DVC3	intact:EBI-21285965	psi-mi:adh1b_human(display_long)|uniprotkb:ADH1B(gene name)|psi-mi:ADH1B(display_short)|uniprotkb:ADH2(gene name synonym)|uniprotkb:Alcohol dehydrogenase subunit beta(gene name synonym)|uniprotkb:Alcohol dehydrogenase 1B(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285970|imex:IM-26899-31	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000659.2|refseq:NP_001273579.1|ensembl:ENSG00000196616.15(gene)|ensembl:ENST00000305046.13(transcript)|go:""GO:0001523""(retinoid metabolic process)|go:""GO:0004022""(""alcohol dehydrogenase (NAD+) activity"")|go:""GO:0004745""(""all-trans-retinol dehydrogenase (NAD+) activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042572""(retinol metabolic process)|go:""GO:0042573""(retinoic acid metabolic process)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|mint:P00325|rcsb pdb:1DEH|rcsb pdb:1HDX|rcsb pdb:1HDY|rcsb pdb:1HDZ|rcsb pdb:1HSZ|rcsb pdb:1HTB|rcsb pdb:1U3U|rcsb pdb:1U3V|rcsb pdb:3HUD|reactome:R-HSA-71384|panther:PTHR43880(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:BYRRhJ4ehC5GphMAq8BFQ2EpNss9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:8DA5149DFE295655|rigid:EuhZ179q4bvO364XMcV8Vmk2Ibk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8IYB9	uniprotkb:Q83D57	intact:EBI-2682172|uniprotkb:Q7Z3I0|intact:EBI-12135433|ensembl:ENSP00000477392.1	intact:EBI-21285947	psi-mi:zn595_human(display_long)|uniprotkb:ZNF595(gene name)|psi-mi:ZNF595(display_short)	psi-mi:q83d57_coxbu(display_long)|uniprotkb:CBU_0885(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285959|imex:IM-26899-365	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001272981.1|refseq:NP_001272982.1|refseq:NP_001272983.1|refseq:NP_872330.1|ensembl:ENSG00000272602.6(gene)|ensembl:ENST00000610261.6(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q8IYB9|reactome:R-HSA-212436|panther:PTHR24377(orthology-group)"	mint:Q83D57|refseq:NP_819902.2|refseq:WP_010957867.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:bw/THTDnw6TEGPE5oJ2kXLiw5Mg9606	rogid:nmEtkvTQxaroeu4VK6t674RWCg0227377	intact-crc:FEF3DE635DBA1398|rigid:BGw4Xg1wlS9MLjV2UUu0oaQ41is	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q1RMZ1	uniprotkb:Q83D09	intact:EBI-21285976|ensembl:ENSP00000297145.4|uniprotkb:Q8N3D0|uniprotkb:Q96MV7	intact:EBI-21285965	psi-mi:samtr_human(display_long)|uniprotkb:SAMTOR(gene name)|psi-mi:SAMTOR(display_short)|uniprotkb:BMT2(gene name synonym)|uniprotkb:C7orf60(gene name synonym)|uniprotkb:Probable methyltransferase BMT2 homolog(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21285995|imex:IM-26899-141	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164603.12(gene)|ensembl:ENST00000297145.9(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1903432""(regulation of TORC1 signaling)|go:""GO:1904047""(S-adenosyl-L-methionine binding)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904263""(positive regulation of TORC1 signaling)|interpro:IPR021867|interpro:IPR029063|mint:Q1RMZ1|reactome:R-HSA-9639288|refseq:NP_689769.2|panther:PTHR21008(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:l8SMJSLuDy0JmAPhAdrG0PdFORI9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:7B29DA0E6A94D8AE|rigid:Tkl5PTtSPT5R0ZQlfPWkt8gvSGo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8N3F9	uniprotkb:Q83D09	intact:EBI-21286031|ensembl:ENSP00000315106.6|uniprotkb:Q86SM2	intact:EBI-21285965	psi-mi:g137c_human(display_long)|uniprotkb:GPR137C(gene name)|psi-mi:GPR137C(display_short)|uniprotkb:TM7SF1L2(gene name synonym)|uniprotkb:Transmembrane 7 superfamily member 1-like 2 protein(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286043|imex:IM-26899-145	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000180998.12(gene)|ensembl:ENST00000321662.11(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:1904263""(positive regulation of TORC1 signaling)|interpro:IPR029723|mint:Q8N3F9|refseq:NP_001093122.1|panther:PTHR15146(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:VAwg00VU+uorrcXewn8A2oJYV6E9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:750550990299CD29|rigid:lg36fVrx0VHPxSnKD1qkyL6O2uw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q32MH5	uniprotkb:Q83D09	intact:EBI-2866142|uniprotkb:Q4G0R7|uniprotkb:Q32MH6|uniprotkb:Q5XJ16|uniprotkb:Q9P2H7|uniprotkb:Q9NV24|uniprotkb:A8KA52|uniprotkb:Q6PDA3|uniprotkb:B4DEP5|uniprotkb:B4DF40|uniprotkb:F5H8G0|ensembl:ENSP00000261844.7|ensembl:ENSP00000484641.1	intact:EBI-21285965	psi-mi:atosa_human(display_long)|uniprotkb:ATOSA(gene name)|psi-mi:ATOSA(display_short)|uniprotkb:FAM214A(gene name synonym)|uniprotkb:KIAA1370(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286019|imex:IM-26899-247	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273424.1|refseq:XP_011520091.1|refseq:NP_062546.2|refseq:XP_005254604.1|refseq:XP_005254605.1|ensembl:ENSG00000047346.13(gene)|ensembl:ENST00000261844.11(transcript)|ensembl:ENST00000619572.5(transcript)|go:""GO:0005634""(nucleus)|interpro:IPR025261|interpro:IPR033473|interpro:IPR051506|mint:Q32MH5|panther:PTHR13199(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:MaU58q95wEB3FxQaY/ri5QKm06M9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:324F690DAA515C86|rigid:j8RZ/Qe63FdMRsQHN5NS8pHAkho	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P45985	uniprotkb:Q83D09	intact:EBI-447868|uniprotkb:D3DTS5|uniprotkb:Q5U0B8|uniprotkb:B2R7N7|uniprotkb:B3KYB2|uniprotkb:Q6FHX4|uniprotkb:Q6P9H2|uniprotkb:Q6PIE6|ensembl:ENSP00000262445.5|intact:EBI-28973354	intact:EBI-21285965	psi-mi:mp2k4_human(display_long)|uniprotkb:JNK-activating kinase 1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase kinase 1(gene name synonym)|uniprotkb:SAPK/ERK kinase 1(gene name synonym)|uniprotkb:MAP2K4(gene name)|psi-mi:MAP2K4(display_short)|uniprotkb:JNKK1(gene name synonym)|uniprotkb:MKK4(gene name synonym)|uniprotkb:PRKMK4(gene name synonym)|uniprotkb:SERK1(gene name synonym)|uniprotkb:MEK4(gene name synonym)|uniprotkb:MAPK/ERK kinase 4(gene name synonym)|uniprotkb:SKK1(gene name synonym)|uniprotkb:SEK1(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 1(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286067|imex:IM-26899-769	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003001.1|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0072709""(cellular response to sorbitol)|go:""GO:0090398""(cellular senescence)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|ensembl:ENSG00000065559.15(gene)|ensembl:ENST00000353533.10(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0008545""(JUN kinase kinase activity)|go:""GO:0009611""(response to wounding)|go:""GO:0030424""(axon)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034390""(smooth muscle cell apoptotic process)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036481""(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0043204""(perikaryon)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0051770""(obsolete positive regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061049""(cell growth involved in cardiac muscle cell development)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P45985|rcsb pdb:3ALN|rcsb pdb:3ALO|rcsb pdb:3VUT|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-5210891|reactome:R-HSA-5684264|refseq:NP_001268364.1|panther:PTHR48013(orthology-group)|ensembl:ENSP00000262445.5|ensembl:ENST00000415385.7|ensembl:ENSP00000410402.3"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:/ndhkIbnc9oTm68r4DwDUyfXDF89606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:C0BF267ACECF9DA5|rigid:pYErYbsb8c3x/ROVjcoqCZMhkrM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8IUZ0	uniprotkb:Q83D09	intact:EBI-9477875|uniprotkb:B7Z366|uniprotkb:G5E9T5|uniprotkb:Q9NXM6|uniprotkb:H0YLN4|uniprotkb:B3KVX1|uniprotkb:F5H1J4|ensembl:ENSP00000260382.4	intact:EBI-21285965	psi-mi:lrc49_human(display_long)|uniprotkb:LRRC49(gene name)|psi-mi:LRRC49(display_short)|uniprotkb:CSTPP2(gene name synonym)|uniprotkb:Centriolar satellite-associated tubulin polyglutamylase complex regulator 2(gene name synonym)|uniprotkb:Tubulin polyglutamylase complex subunit 4(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286055|imex:IM-26899-767	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011520017.1|refseq:XP_016877847.1|refseq:NP_001271286.1|refseq:NP_001185946.1|refseq:NP_001185947.1|refseq:NP_060161.2|ensembl:ENSG00000137821.12(gene)|ensembl:ENST00000260382.10(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005874""(microtubule)|go:""GO:0034451""(centriolar satellite)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR025875|interpro:IPR032675|interpro:IPR050576|mint:Q8IUZ0|reactome:R-HSA-8955332|panther:PTHR45973(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:6e+i7lca3hMpmbOQuv8GkDVEfoM9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:5397B362A59A3B95|rigid:ZrfgY0xDzQuabSkz8WGMt3E4mE0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UJC3	uniprotkb:Q83D09	intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8K8E9|ensembl:ENSP00000360252.3|uniprotkb:A8MU44|uniprotkb:B4DX15|intact:EBI-10969618	intact:EBI-21285965	psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286049|imex:IM-26899-467	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056972.1|ensembl:ENSG00000134709.13(gene)|ensembl:ENST00000371208.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005874""(microtubule)|go:""GO:0007030""(Golgi organization)|go:""GO:0007032""(endosome organization)|go:""GO:0007040""(lysosome organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0015031""(protein transport)|go:""GO:0030705""(cytoskeleton-dependent intracellular transport)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0051959""(dynein light intermediate chain binding)|go:""GO:0070695""(FHF complex)|go:""GO:1905198""(manchette assembly)|go:""GO:1905719""(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3|panther:PTHR18947(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:2D68B5A361545A8D|rigid:jtGwjOUXN4uyItWKVbk7gbPMBGw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P24530	uniprotkb:Q83D09	intact:EBI-6624656|uniprotkb:A2A2Z8|uniprotkb:A8K3T4|uniprotkb:O15343|uniprotkb:Q59GB1|uniprotkb:Q5W0G9|uniprotkb:Q8NHM6|uniprotkb:Q8NHM7|uniprotkb:Q8NHM8|uniprotkb:Q8NHM9|uniprotkb:Q9UD23|uniprotkb:Q9UQK3|ensembl:ENSP00000487082.2|ensembl:ENSP00000493527.1|ensembl:ENSP00000493895.1|ensembl:ENSP00000494278.1	intact:EBI-21285965	psi-mi:ednrb_human(display_long)|uniprotkb:EDNRB(gene name)|psi-mi:EDNRB(display_short)|uniprotkb:ETRB(gene name synonym)|uniprotkb:Endothelin receptor non-selective type(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286007|imex:IM-26899-763	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:388""|efo:""Orphanet:895""|efo:""Orphanet:897""|rcsb pdb:8IY5|rcsb pdb:8IY6|rcsb pdb:8XGR|rcsb pdb:8XVE|rcsb pdb:8XVH|rcsb pdb:8XWP|rcsb pdb:8XWQ|rcsb pdb:8ZRT|reactome:R-HSA-375276|ensembl:ENSG00000136160.17(gene)|ensembl:ENST00000475537.2(transcript)|ensembl:ENST00000646605.1(transcript)|ensembl:ENST00000646607.2(transcript)|ensembl:ENST00000646948.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001755""(neural crest cell migration)|go:""GO:0002001""(renin secretion into blood stream)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0004962""(endothelin receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006885""(regulation of pH)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007194""(negative regulation of adenylate cyclase activity)|go:""GO:0007200""(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007399""(nervous system development)|go:""GO:0007422""(peripheral nervous system development)|go:""GO:0007497""(posterior midgut development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010467""(gene expression)|go:""GO:0014043""(negative regulation of neuron maturation)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0014826""(vein smooth muscle contraction)|go:""GO:0017046""(peptide hormone binding)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0030202""(heparin proteoglycan metabolic process)|go:""GO:0030318""(melanocyte differentiation)|go:""GO:0031620""(regulation of fever generation)|go:""GO:0031702""(type 1 angiotensin receptor binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032341""(aldosterone metabolic process)|go:""GO:0035645""(enteric smooth muscle cell differentiation)|go:""GO:0035810""(positive regulation of urine volume)|go:""GO:0035812""(renal sodium excretion)|go:""GO:0042045""(epithelial fluid transport)|go:""GO:0042310""(vasoconstriction)|go:""GO:0042311""(vasodilation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0048066""(developmental pigmentation)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0048265""(response to pain)|go:""GO:0048484""(enteric nervous system development)|go:""GO:0050678""(regulation of epithelial cell proliferation)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060406""(positive regulation of penile erection)|go:""GO:0061028""(establishment of endothelial barrier)|go:""GO:0070294""(renal sodium ion absorption)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0072112""(podocyte differentiation)|go:""GO:0086100""(endothelin receptor signaling pathway)|go:""GO:0097018""(renal albumin absorption)|go:""GO:0097402""(neuroblast migration)|go:""GO:0160093""(chordate pharynx development)|go:""GO:1904383""(response to sodium phosphate)|go:""GO:1990839""(response to endothelin)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000499(Endothelin receptor)|interpro:IPR001112(Endothelin B receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR051193|mint:P24530|rcsb pdb:5GLH|rcsb pdb:5GLI|rcsb pdb:5X93|rcsb pdb:5XPR|rcsb pdb:6IGK|rcsb pdb:6IGL|rcsb pdb:6LRY|rcsb pdb:8HBD|rcsb pdb:8HCX|reactome:R-HSA-416476|reactome:R-HSA-9856649|refseq:NP_000106.1|refseq:NP_001116131.1|refseq:NP_001188326.1|refseq:NP_003982.1|panther:PTHR46099(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:EVPfuNkUH6NzN8Jo1EjipkRmqSU9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:6D07031654B8BE6C|rigid:i8kmD8Pap5xoboLJ4h4HvJ7WInk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O60739	uniprotkb:Q83D09	intact:EBI-1043343|uniprotkb:Q9UQF8|ensembl:ENSP00000232905.3	intact:EBI-21285965	psi-mi:eif1b_human(display_long)|uniprotkb:Protein translation factor SUI1 homolog GC20(gene name synonym)|uniprotkb:EIF1B(gene name)|psi-mi:EIF1B(display_short)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286013|imex:IM-26899-143	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005866.1|ensembl:ENSG00000114784.4(gene)|ensembl:ENST00000232905.4(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0043024""(ribosomal small subunit binding)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005874(Eukaryotic translation initiation factor SUI1)|interpro:IPR036877|mint:O60739|panther:PTHR10388(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:0nnqCaTD/q0KhGcITR0LD7WLET09606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:F2582001BE099992|rigid:rw5O6tnIyE4XcCDKbDSJ/delB9w	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y680	uniprotkb:Q83D09	intact:EBI-3918971|uniprotkb:Q96DA4|uniprotkb:Q9Y6B0|uniprotkb:Q86U65|uniprotkb:Q6V3B2|uniprotkb:Q4ZG70|ensembl:ENSP00000413152.2	intact:EBI-21285965	psi-mi:fkbp7_human(display_long)|uniprotkb:FKBP7(gene name)|psi-mi:FKBP7(display_short)|uniprotkb:FKBP23(gene name synonym)|uniprotkb:23 kDa FK506-binding protein(gene name synonym)|uniprotkb:FK506-binding protein 7(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:UNQ670/PRO1304(orf name)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286025|imex:IM-26899-765	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001128684.1|refseq:NP_851939.1|ensembl:ENSG00000079150.19(gene)|ensembl:ENST00000424785.7(transcript)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005528""(FK506 binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR046357|interpro:IPR052273|mint:Q9Y680|panther:PTHR46222(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:HJ80Z7OSdidxr1a/p1IYSkVMGGY9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:E58FCDFA90606DA2|rigid:tKt1ILLay6oHU46BKrOmRLfp02U	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9P0M9	uniprotkb:Q83D09	intact:EBI-5325236|uniprotkb:B2RE14|ensembl:ENSP00000225969.4	intact:EBI-21285965	psi-mi:rm27_human(display_long)|uniprotkb:MRPL27(gene name)|psi-mi:MRPL27(display_short)|uniprotkb:39S ribosomal protein L27, mitochondrial(gene name synonym)|uniprotkb:HSPC250(orf name)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286073|imex:IM-26899-367	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057588.1|rcsb pdb:7O9K|ensembl:ENSG00000108826.16(gene)|ensembl:ENST00000225969.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005762""(mitochondrial large ribosomal subunit)|go:""GO:0006412""(translation)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR001684(Ribosomal protein L27)|mint:Q9P0M9|rcsb pdb:3IY9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:7O9M|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:7OI6|rcsb pdb:7OI7|rcsb pdb:7OI8|rcsb pdb:7OI9|rcsb pdb:7OIA|rcsb pdb:7OIB|rcsb pdb:7OIC|rcsb pdb:7OID|rcsb pdb:7OIE|rcsb pdb:7PD3|rcsb pdb:7PO4|rcsb pdb:7QH6|rcsb pdb:7QH7|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8K2A|rcsb pdb:8K2B|rcsb pdb:8OIR|rcsb pdb:8OIT|rcsb pdb:8PK0|rcsb pdb:8QSJ|rcsb pdb:8QU1|rcsb pdb:8QU5|rcsb pdb:8XT0|rcsb pdb:8XT1|rcsb pdb:8XT2|rcsb pdb:8XT3|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR15893(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:Tb7r8GeSkNdNN6aY2mvmTR4MFmc9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:2A87D9EFA7D0BDE5|rigid:ohyKnpKBA4F1sIsSdMMifTp6SfI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P33908	uniprotkb:Q83D09	intact:EBI-12586254|ensembl:ENSP00000357453.3|uniprotkb:E7EU32|uniprotkb:Q6P052|uniprotkb:Q9NU44|uniprotkb:Q9UJI3	intact:EBI-21285965	"psi-mi:ma1a1_human(display_long)|uniprotkb:MAN1A1(gene name)|psi-mi:MAN1A1(display_short)|uniprotkb:""Man(9)-alpha-mannosidase""(gene name synonym)|uniprotkb:Mannosidase alpha class 1A member 1(gene name synonym)|uniprotkb:Processing alpha-1,2-mannosidase IA(gene name synonym)"	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286061|imex:IM-26899-469	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111885.7(gene)|ensembl:ENST00000368468.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004571""(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006486""(protein glycosylation)|go:""GO:0015923""(mannosidase activity)|go:""GO:0016020""(membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0036503""(ERAD pathway)|go:""GO:0045047""(protein targeting to ER)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904381""(Golgi apparatus mannose trimming)|go:""GO:1904382""(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR050749|mint:P33908|reactome:R-HSA-6811438|reactome:R-HSA-964827|panther:PTHR11742(orthology-group)|refseq:NP_005898.2"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:fmBa7NZdVy2Ou9DtEO2K1/T0AHw9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:C783655666F0E0EE|rigid:lKP3qZiuvxsy1ciDiiUCr5wzns4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5T2W1	uniprotkb:Q83D09	intact:EBI-349819|uniprotkb:O60450|uniprotkb:Q5T5P6|uniprotkb:Q9BQ41|uniprotkb:B4DPB9|uniprotkb:E7EU02|ensembl:ENSP00000342143.2|ensembl:ENSP00000394485.1	intact:EBI-21285965	"psi-mi:nhrf3_human(display_long)|uniprotkb:PDZK1(gene name)|psi-mi:PDZK1(display_short)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:""Na(+)/H(+) exchanger regulatory factor 3""(gene name synonym)|uniprotkb:CAP70(gene name synonym)|uniprotkb:NHERF3(gene name synonym)|uniprotkb:PDZD1(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym)"	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286097|imex:IM-26899-147	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188254.1|refseq:NP_002605.2|refseq:NP_001188255.1|ensembl:ENSG00000174827.14(gene)|ensembl:ENST00000344770.6(transcript)|ensembl:ENST00000417171.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005124""(scavenger receptor binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0015879""(carnitine transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0031526""(brush border membrane)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032414""(positive regulation of ion transmembrane transporter activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044070""(regulation of monoatomic anion transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:1904064""(positive regulation of cation transmembrane transport)|go:""GO:1905477""(positive regulation of protein localization to membrane)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051067|mint:Q5T2W1|rcsb pdb:2EEI|rcsb pdb:2EEJ|rcsb pdb:2VSP|rcsb pdb:3TMH|rcsb pdb:4Q2P|rcsb pdb:6EZI|refseq:XP_016856953.1|panther:PTHR14191(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:sU0SZ8m9Or0LFmLo9dh6B7RBJWs9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:2D67FC684B51C2DF|rigid:agw6Gkzglq28fUXdlC2V6Wi+nw4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O15355	uniprotkb:Q83D09	intact:EBI-725702|ensembl:ENSP00000342778.4	intact:EBI-21285965	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286103|imex:IM-26899-33	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_817092.1|dip:DIP-29404N|ensembl:ENSG00000115241.11(gene)|ensembl:ENST00000344034.5(transcript)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0035970""(peptidyl-threonine dephosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|panther:PTHR13832(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/01	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:A32BCDD53D7CC951|rigid:uMqRvA+74R5rYxYbcTqwVG8fhRs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96BW5	uniprotkb:Q83D09	intact:EBI-4291023|uniprotkb:B0YJ77|uniprotkb:B3KTF5|uniprotkb:D3DRU0|uniprotkb:Q9BY46|ensembl:ENSP00000367239.1|ensembl:ENSP00000439485.1	intact:EBI-21285965	psi-mi:pter_human(display_long)|uniprotkb:Phosphotriesterase-related protein(gene name synonym)|uniprotkb:PTER(gene name)|psi-mi:PTER(display_short)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286109|imex:IM-26899-251	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001001484.1|refseq:NP_109589.2|refseq:NP_001248765.1|refseq:NP_001248766.1|refseq:NP_001248767.1|ensembl:ENSG00000165983.15(gene)|ensembl:ENST00000378000.5(transcript)|ensembl:ENST00000535784.7(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009056""(catabolic process)|go:""GO:0019530""(taurine metabolic process)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0032098""(regulation of appetite)|go:""GO:0070062""(extracellular exosome)|go:""GO:0141215""(N-acetyltaurine hydrolase activity)|interpro:IPR001559(Aryldialkylphosphatase)|interpro:IPR017947|interpro:IPR032466|mint:Q96BW5|refseq:XP_016872418.1|refseq:XP_016872419.1|panther:PTHR10819(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:znA1p3a8Ksrqx2dDHiAegKP5JaY9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:39535A7E8220340B|rigid:gOsU8/1C29ji/3MUj8uT7T9CdF4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y2A7	uniprotkb:Q83D09	intact:EBI-389845|uniprotkb:O60329|uniprotkb:Q53QN5|uniprotkb:Q53S94|uniprotkb:Q53Y35|ensembl:ENSP00000355348.3	intact:EBI-21285965	psi-mi:nckp1_human(display_long)|uniprotkb:NCKAP1(gene name)|psi-mi:NCKAP1(display_short)|uniprotkb:HEM2(gene name synonym)|uniprotkb:KIAA0587(gene name synonym)|uniprotkb:NAP1(gene name synonym)|uniprotkb:p125Nap1(gene name synonym)|uniprotkb:Membrane-associated protein HEM-2(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286079|imex:IM-26899-369	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR12093(orthology-group)|refseq:NP_038464.1|refseq:NP_995314.1|ensembl:ENSG00000061676.16(gene)|ensembl:ENST00000361354.9(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001726""(ruffle)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006915""(apoptotic process)|go:""GO:0007417""(central nervous system development)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031209""(SCAR complex)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031941""(filamentous actin)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000601""(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR019137|mint:Q9Y2A7|rcsb pdb:3P8C|rcsb pdb:4N78|rcsb pdb:7USC|rcsb pdb:7USD|rcsb pdb:7USE|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|dip:DIP-31119N"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/01	rogid:xj4ySr6cf374UbE/gfuxMx1X0tw9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:50FAA5D5349F7709|rigid:+itzX9GOtgkliwdRuwiK3zebxjM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P51003	uniprotkb:Q83D09	intact:EBI-359376|uniprotkb:Q86SX4|uniprotkb:Q86TV0|uniprotkb:Q8IYF5|uniprotkb:Q9BVU2|ensembl:ENSP00000216277.8	intact:EBI-21285965	psi-mi:papoa_human(display_long)|uniprotkb:PAPOLA(gene name)|psi-mi:PAPOLA(display_short)|uniprotkb:PAP(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase alpha(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286091|imex:IM-26899-573	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_116021.2|refseq:NP_001238935.1|refseq:NP_001238936.1|refseq:NP_001280556.1|refseq:NP_001280557.1|refseq:NP_001280561.1|ensembl:ENSG00000090060.19(gene)|ensembl:ENST00000216277.13(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0030145""(manganese ion binding)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0180010""(co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway)|go:""GO:0180011""(cytosolic mRNA polyadenylation)|go:""GO:1990817""(""poly(A) RNA polymerase activity"")|interpro:IPR007010(""Poly(A) polymerase, RNA-binding region"")|interpro:IPR007012(""Poly(A) polymerase, central region"")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR014492(""Poly(A) polymerase"")|interpro:IPR043519|interpro:IPR048840|mint:P51003|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-27610N|dip:DIP-40865N|panther:PTHR10682(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/27	rogid:rRMBZRE1yFjnO+pnz5g4k+u7hwo9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:6F53A3DCC963FE92|rigid:fxlKj41Xm/K92AlaxH3uYNP0N3s	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UQ80	uniprotkb:Q83D09	intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886.6	intact:EBI-21285965	psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286085|imex:IM-26899-249	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006182.2|ensembl:ENSG00000170515.14(gene)|ensembl:ENST00000303305.11(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006364""(rRNA processing)|go:""GO:0006417""(regulation of translation)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR018349|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|interpro:IPR047113|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:8K2C|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|reactome:R-HSA-6798695|dip:DIP-31275N|panther:PTHR10804(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/27	rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:8DBA14D2240C30A5|rigid:2Cx9ji5CNRGHf9ct5P+Emiy5pIs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P41220	uniprotkb:Q83D09	intact:EBI-712388|intact:EBI-1050416|uniprotkb:Q6I9U5|ensembl:ENSP00000235382.5	intact:EBI-21285965	psi-mi:rgs2_human(display_long)|uniprotkb:G0/G1 switch regulatory protein 8(gene name synonym)|uniprotkb:RGS2(gene name)|psi-mi:RGS2(display_short)|uniprotkb:G0S8(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 31 protein(gene name synonym)|uniprotkb:GIG31(orf name)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286115|imex:IM-26899-575	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002914.1|ensembl:ENSG00000116741.8(gene)|ensembl:ENST00000235382.7(transcript)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010519""(negative regulation of phospholipase activity)|go:""GO:0010614""(negative regulation of cardiac muscle hypertrophy)|go:""GO:0010855""(adenylate cyclase inhibitor activity)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0045471""(response to ethanol)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0050873""(brown fat cell differentiation)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060087""(relaxation of vascular associated smooth muscle)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0060452""(positive regulation of cardiac muscle contraction)|go:""GO:0061052""(negative regulation of cell growth involved in cardiac muscle cell development)|go:""GO:0071877""(regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway)|go:""GO:1900924""(negative regulation of glycine import across plasma membrane)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR034947|interpro:IPR036305|interpro:IPR044926|mint:P41220|rcsb pdb:2AF0|rcsb pdb:2V4Z|rcsb pdb:4EKC|rcsb pdb:4EKD|reactome:R-HSA-416476|dip:DIP-44289N|panther:PTHR10845(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:7tdfhNRRyaPKS2taH6iurdHCZ+s9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:64F026CF0E044906|rigid:gfWKBbLVsbohGyzKngG4Sx69nxM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NQG5	uniprotkb:Q83D09	intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532.4	intact:EBI-21285965	psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286121|imex:IM-26899-35	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067038.1|ensembl:ENSG00000101413.12(gene)|ensembl:ENST00000373433.9(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001111""(RNA polymerase II promoter clearance)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010564""(regulation of cell cycle process)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0042802""(identical protein binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0097550""(transcription preinitiation complex)|go:""GO:0099122""(RNA polymerase II C-terminal domain binding)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|interpro:IPR047882|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|rcsb pdb:9B9L|reactome:R-HSA-6807505|dip:DIP-61537N|panther:PTHR12460(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/27	rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:080713E334E1912D|rigid:F8egyHraxMj4DDcQZxH1SlA8VIo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NY72	uniprotkb:Q83D09	intact:EBI-17247926|uniprotkb:A5H1I5|uniprotkb:Q17RL3|uniprotkb:Q9ULR2|ensembl:ENSP00000299333.3|ensembl:ENSP00000376523.2|ensembl:ENSP00000432785.1|ensembl:ENSP00000499439.1|ensembl:ENSP00000499755.1	intact:EBI-21285965	psi-mi:scn3b_human(display_long)|uniprotkb:SCN3B(gene name)|psi-mi:SCN3B(display_short)|uniprotkb:KIAA1158(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286133|imex:IM-26899-149	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR10546(orthology-group)|efo:""Orphanet:130""|efo:""Orphanet:334""|ensembl:ENSG00000166257.10(gene)|ensembl:ENST00000299333.8(transcript)|ensembl:ENST00000392770.6(transcript)|ensembl:ENST00000530277.5(transcript)|ensembl:ENST00000657123.1(transcript)|ensembl:ENST00000657191.1(transcript)|go:""GO:0001518""(voltage-gated sodium channel complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006814""(sodium ion transport)|go:""GO:0007399""(nervous system development)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010765""(positive regulation of sodium ion transport)|go:""GO:0016020""(membrane)|go:""GO:0017080""(sodium channel regulator activity)|go:""GO:0019871""(sodium channel inhibitor activity)|go:""GO:0030018""(Z disc)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051899""(membrane depolarization)|go:""GO:0060048""(cardiac muscle contraction)|go:""GO:0060371""(regulation of atrial cardiac muscle cell membrane depolarization)|go:""GO:0060373""(regulation of ventricular cardiac muscle cell membrane depolarization)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086005""(ventricular cardiac muscle cell action potential)|go:""GO:0086006""(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:""GO:0086010""(membrane depolarization during action potential)|go:""GO:0086012""(membrane depolarization during cardiac muscle cell action potential)|go:""GO:0086014""(atrial cardiac muscle cell action potential)|go:""GO:0086015""(SA node cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR027098|interpro:IPR036179|mint:Q9NY72|rcsb pdb:4L1D|rcsb pdb:7TJ8|rcsb pdb:7TJ9|reactome:R-HSA-445095|reactome:R-HSA-5576892|refseq:NP_001035241.1|refseq:NP_060870.1|refseq:XP_011541199.1"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:JibaGARh6xabzhHZEf16XAaUgOg9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:B5EE9BA894AA2F84|rigid:JZ8mJzl+F7ziEoyorwBxIaYOrgw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96CM3	uniprotkb:Q83D09	intact:EBI-7825200|uniprotkb:E9PML2|uniprotkb:Q96K56|intact:MINT-8052462|intact:EBI-11113381|ensembl:ENSP00000298317.4	intact:EBI-21285965	psi-mi:rusd4_human(display_long)|uniprotkb:RPUSD4(gene name)|psi-mi:RPUSD4(display_short)|uniprotkb:RNA pseudouridylate synthase domain-containing protein 4(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286127|imex:IM-26899-471	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_116184.2|refseq:NP_001138299.1|ensembl:ENSG00000165526.9(gene)|ensembl:ENST00000298317.9(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009982""(pseudouridine synthase activity)|go:""GO:0031118""(rRNA pseudouridine synthesis)|go:""GO:0035770""(ribonucleoprotein granule)|go:""GO:0070131""(positive regulation of mitochondrial translation)|go:""GO:0070902""(mitochondrial tRNA pseudouridine synthesis)|go:""GO:0106029""(tRNA pseudouridine synthase activity)|go:""GO:1990400""(mitochondrial ribosomal large subunit rRNA binding)|go:""GO:1990481""(mRNA pseudouridine synthesis)|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR006224(Pseudouridine synthase, conserved site)|interpro:IPR020103|interpro:IPR050188|mint:Q96CM3|rcsb pdb:5UBA|panther:PTHR21600(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	comment:mint	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/28	rogid:UxJTvd9B7xEGEh9W7niR/AAOdLM9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:779288F2DDCC5486|rigid:pU3QXjSrceLg7jJRWnYFhw/jhvY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P35555	uniprotkb:B5QSC8	intact:EBI-2505934|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6|ensembl:ENSP00000325527.5	intact:EBI-21286181	psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym)	psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286209|imex:IM-26899-681	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1885""|efo:""Orphanet:2084""|efo:""Orphanet:2462""|efo:""Orphanet:2623""|efo:""Orphanet:2833""|efo:""Orphanet:284963""|efo:""Orphanet:284979""|efo:""Orphanet:300382""|efo:""Orphanet:3449""|efo:""Orphanet:91387""|efo:""Orphanet:969""|dip:DIP-29985N|ensembl:ENSG00000166147.16(gene)|ensembl:ENST00000316623.10(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001527""(microfibril)|go:""GO:0001656""(metanephros development)|go:""GO:0005178""(integrin binding)|go:""GO:0005179""(hormone activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010467""(gene expression)|go:""GO:0030023""(extracellular matrix constituent conferring elasticity)|go:""GO:0031012""(extracellular matrix)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035582""(sequestering of BMP in extracellular matrix)|go:""GO:0035583""(sequestering of TGFbeta in extracellular matrix)|go:""GO:0042802""(identical protein binding)|go:""GO:0043010""(camera-type eye development)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0048286""(lung alveolus development)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:1990314""(cellular response to insulin-like growth factor stimulus)|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|interpro:IPR049388|interpro:IPR049883|interpro:IPR052080|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|panther:PTHR24039(orthology-group)"	"mint:B5QSC8|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/28	rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606	rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377	intact-crc:838CF29313217D21|rigid:7zJeBA7nOENsbxn4DvQGXfyBWBg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H8H3	uniprotkb:B5QSC8	intact:EBI-1390168|uniprotkb:Q9H7R3|uniprotkb:Q9UHZ7|uniprotkb:Q9Y422|ensembl:ENSP00000331787.4|ensembl:ENSP00000447542.1|ensembl:ENSP00000448785.1	intact:EBI-21286181	psi-mi:tmt1a_human(display_long)|uniprotkb:TMT1A(gene name)|psi-mi:TMT1A(display_short)|uniprotkb:METTL7A(gene name synonym)|uniprotkb:Methyltransferase-like protein 7A(gene name synonym)|uniprotkb:Protein AAM-B(gene name synonym)|uniprotkb:Thiol methyltransferase 1A(gene name synonym)|uniprotkb:PRO0066(orf name)|uniprotkb:UNQ1902/PRO4348(orf name)|uniprotkb:N6-adenosine-methyltransferase TMT1A(gene name synonym)	psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286221|imex:IM-26899-577	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_054752.3|refseq:XP_006719395.1|ensembl:ENSG00000185432.12(gene)|ensembl:ENST00000332160.5(transcript)|ensembl:ENST00000547104.1(transcript)|ensembl:ENST00000548553.1(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001734""(""mRNA m(6)A methyltransferase activity"")|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0008173""(RNA methyltransferase activity)|go:""GO:0016020""(membrane)|go:""GO:0018708""(thiol S-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0042476""(odontogenesis)|go:""GO:0180035""(lncRNA processing)|go:""GO:1904724""(tertiary granule lumen)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|interpro:IPR052356|mint:Q9H8H3|reactome:R-HSA-6798695|panther:PTHR42912(orthology-group)"	"mint:B5QSC8|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:b8PnE+BClVn1MzOlg0uIaqDSOaU9606	rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377	intact-crc:171A06C11ED0E0AB|rigid:/QPQcpHWaAagTAXKs7z8nSAOtfo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95171	uniprotkb:Q83C21	intact:EBI-7543896|uniprotkb:B7Z797|intact:MINT-8162407|intact:UNK-5430852|uniprotkb:Q86X00|intact:UNK-5458327|uniprotkb:Q53H61|uniprotkb:F5H651|uniprotkb:Q5W0S8|uniprotkb:Q5W0S9|intact:MINT-3975264|ensembl:ENSP00000302579.5	intact:EBI-21286157	psi-mi:scel_human(display_long)|uniprotkb:SCEL(gene name)|psi-mi:SCEL(display_short)	psi-mi:q83c21_coxbu(display_long)|uniprotkb:CBU_1314(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286175|imex:IM-26899-477	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_659001.2|refseq:NP_001154178.1|refseq:NP_003834.3|ensembl:ENSG00000136155.17(gene)|ensembl:ENST00000349847.4(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0008544""(epidermis development)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0009792""(embryo development ending in birth or egg hatching)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR052621|mint:O95171|panther:PTHR15468(orthology-group)"	mint:Q83C21|refseq:NP_820305.2|refseq:WP_010958144.1	-	comment:mint|function:May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/22	rogid:1sNj7h14CEpm44d5qulY/tWlYgE9606	rogid:DIFe5BH2MWRB3uuIhKXumw9z8+w227377	intact-crc:F186BAD6FC2F0B22|rigid:ndPUKDlOUA61iEIMN6+XnDGzYyI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P22307	uniprotkb:Q83D09	intact:EBI-1050999|uniprotkb:Q15432|uniprotkb:Q16622|uniprotkb:Q99430|uniprotkb:Q5VVZ1|uniprotkb:D3DQ37|uniprotkb:Q6NXF4|uniprotkb:B4DHP6|uniprotkb:A6NM69|uniprotkb:B4DGJ9|uniprotkb:C9JC79|uniprotkb:E1B6W5|uniprotkb:F2Z3J1|ensembl:ENSP00000360569.3	intact:EBI-21285965	psi-mi:scp2_human(display_long)|uniprotkb:Propanoyl-CoA C-acyltransferase(gene name synonym)|uniprotkb:Sterol carrier protein X(gene name synonym)|uniprotkb:SCP-chi(gene name synonym)|uniprotkb:SCPX(gene name synonym)|uniprotkb:SCP2(gene name)|psi-mi:SCP2(display_short)|uniprotkb:Acetyl-CoA C-myristoyltransferase(gene name synonym)|uniprotkb:Non-specific lipid-transfer protein(gene name synonym)|uniprotkb:SCP-2/3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:SCP-2/thiolase(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286139|imex:IM-26899-679	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:163684""|ensembl:ENSG00000116171.19(gene)|ensembl:ENST00000371514.8(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0003988""(acetyl-CoA C-acyltransferase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0006694""(steroid biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0006701""(progesterone biosynthetic process)|go:""GO:0008206""(bile acid metabolic process)|go:""GO:0008526""(phosphatidylinositol transfer activity)|go:""GO:0015485""(cholesterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0016020""(membrane)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032385""(positive regulation of intracellular cholesterol transport)|go:""GO:0032959""(inositol trisphosphate biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033540""(fatty acid beta-oxidation using acyl-CoA oxidase)|go:""GO:0033814""(propanoyl-CoA C-acyltransferase activity)|go:""GO:0036042""(long-chain fatty acyl-CoA binding)|go:""GO:0036109""(alpha-linolenic acid metabolic process)|go:""GO:0045940""(positive regulation of steroid metabolic process)|go:""GO:0050632""(propionyl-CoA C2-trimethyltridecanoyltransferase activity)|go:""GO:0050633""(acetyl-CoA C-myristoyltransferase activity)|go:""GO:0070538""(oleic acid binding)|go:""GO:0071071""(regulation of phospholipid biosynthetic process)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0120019""(phosphatidylcholine transfer activity)|go:""GO:0120020""(cholesterol transfer activity)|go:""GO:1901373""(lipid hydroperoxide transport)|interpro:IPR003033(Sterol-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR036527|interpro:IPR055140|mint:P22307|rcsb pdb:1QND|rcsb pdb:2C0L|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-9033241|reactome:R-HSA-9033500|refseq:NP_001007099.1|refseq:NP_001007100.1|refseq:NP_001007101.1|refseq:NP_001007251.1|refseq:NP_001180528.1|refseq:NP_001180546.1|refseq:NP_002970.2|refseq:XP_016857535.1|panther:PTHR24314(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:Vwnu7RuD/2qhcH55Fl9v2TMErtc9606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:E1246C6D8894046B|rigid:vCBOa7rzNaWM+UTAwS/5Y7E5yBg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBS4	uniprotkb:B5QSC8	intact:EBI-713113|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6|ensembl:ENSP00000265028.3|ensembl:ENSP00000414398.1	intact:EBI-21286181	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286203|imex:IM-26899-373	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090520.12(gene)|ensembl:ENST00000265028.8(transcript)|ensembl:ENST00000439351.5(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006457""(protein folding)|go:""GO:0016020""(membrane)|go:""GO:0016556""(mRNA modification)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051604""(protein maturation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0101031""(protein folding chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|interpro:IPR051736|mint:Q9UBS4|reactome:R-HSA-381038|refseq:NP_057390.1|efo:""Orphanet:730""|dip:DIP-29678N|panther:PTHR44298(orthology-group)"	"mint:B5QSC8|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/01	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377	intact-crc:A591DD69B9A81F21|rigid:6CQRbD8fYUXhsGSNTTzGPcOJgEs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UIF8	uniprotkb:B5QSC8	intact:EBI-741542|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8|ensembl:ENSP00000376534.2	intact:EBI-21286181	psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym)	psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286191|imex:IM-26899-371	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_038478.2|refseq:NP_001276904.1|rcsb pdb:4CUP|rcsb pdb:4CUQ|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ7|rcsb pdb:5CQ6|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5E9Y|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBN|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|ensembl:ENSG00000123636.20(gene)|ensembl:ENST00000392783.7(transcript)|rcsb pdb:5PC9|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006338""(chromatin remodeling)|rcsb pdb:5PCA|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|rcsb pdb:5PCB|rcsb pdb:5PCC|go:""GO:0046872""(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PCG|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5PD2|rcsb pdb:5PD3|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PDX|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PEQ|rcsb pdb:5PER|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PFM|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|rcsb pdb:7Q42|rcsb pdb:7WIN|panther:PTHR45915(orthology-group)"	"mint:B5QSC8|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606	rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377	intact-crc:5617D0F167F4627C|rigid:1vlq7GDPBDZ8HCt4LdHzet0EKoU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8N4F4	uniprotkb:Q83D09	intact:EBI-740525|ensembl:ENSP00000480336.1|uniprotkb:A0A087WWM3|uniprotkb:C9JC66	intact:EBI-21285965	psi-mi:s22ao_human(display_long)|uniprotkb:SLC22A24(gene name)|psi-mi:SLC22A24(display_short)|uniprotkb:Solute carrier family 22 member 24(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286145|imex:IM-26899-473	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_775857.2|ensembl:ENSG00000197658.9(gene)|ensembl:ENST00000612278.4(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0008202""(steroid metabolic process)|go:""GO:0015711""(organic anion transport)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0035382""(sterol transmembrane transport)|interpro:IPR005828(General substrate transporter)|interpro:IPR020846|interpro:IPR036259|mint:Q8N4F4|refseq:NP_001129978.2|panther:PTHR24064(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:p413cx5Lhyt5J082RAt1u82SJ609606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:D80D4D48220C021C|rigid:Ml7w3DS8XSGAbQ6+QoaeVF/9/Ec	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75534	uniprotkb:B5QSC8	intact:EBI-719186|uniprotkb:O94961|uniprotkb:Q5TF04|uniprotkb:Q5TF05|uniprotkb:Q68DI9|uniprotkb:Q9Y2S4|uniprotkb:E9PGZ0|uniprotkb:Q68DF1|intact:EBI-1059183|uniprotkb:A8K281|ensembl:ENSP00000351329.4|ensembl:ENSP00000407724.3|ensembl:ENSP00000432958.1|ensembl:ENSP00000508874.1|ensembl:ENSP00000509808.1|ensembl:ENSP00000510208.1|uniprotkb:G5E9Q2|intact:EBI-21358614	intact:EBI-21286181	psi-mi:csde1_human(display_long)|uniprotkb:Protein UNR(gene name synonym)|uniprotkb:N-ras upstream gene protein(gene name synonym)|uniprotkb:CSDE1(gene name)|psi-mi:CSDE1(display_short)|uniprotkb:D1S155E(gene name synonym)|uniprotkb:KIAA0885(gene name synonym)|uniprotkb:NRU(gene name synonym)|uniprotkb:UNR(gene name synonym)	psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286197|imex:IM-26899-153	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001007554.1|refseq:NP_001123995.1|refseq:NP_001229820.1|refseq:NP_001229821.1|refseq:NP_001229822.1|refseq:NP_009089.4|ensembl:ENSG00000009307.17(gene)|ensembl:ENST00000358528.9(transcript)|ensembl:ENST00000438362.7(transcript)|ensembl:ENST00000534699.5(transcript)|ensembl:ENST00000689217.1(transcript)|ensembl:ENST00000689989.1(transcript)|ensembl:ENST00000692719.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0008584""(male gonad development)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0034063""(stress granule assembly)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0070937""(CRD-mediated mRNA stability complex)|go:""GO:0070966""(nuclear-transcribed mRNA catabolic process, no-go decay)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0106002""(mCRD-mediated mRNA stability complex)|go:""GO:0106222""(lncRNA binding)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1905172""(RISC complex binding)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|interpro:IPR024642|mint:O75534|rcsb pdb:1WFQ|rcsb pdb:1X65|rcsb pdb:2YTV|rcsb pdb:2YTX|rcsb pdb:2YTY|panther:PTHR12913(orthology-group)"	"mint:B5QSC8|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:fpL1bONjNXyXjIO/akUIIoeEGTc9606	rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377	intact-crc:3F7CE36CD05CE62B|rigid:job8K3BVcpZQlM7F+wlDdGUZr0U	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y5V3	uniprotkb:B5QSC8	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333.8|ensembl:ENSP00000364874.1|ensembl:ENSP00000364927.3	intact:EBI-21286181	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286215|imex:IM-26899-375	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSG00000179222.18(gene)|ensembl:ENST00000326587.12(transcript)|ensembl:ENST00000375722.5(transcript)|ensembl:ENST00000375772.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0090190""(positive regulation of branching involved in ureteric bud morphogenesis)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:2001235""(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|reactome:R-HSA-9768919|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|panther:PTHR11736(orthology-group)"	"mint:B5QSC8|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377	intact-crc:629A015A9EA8E3E7|rigid:2CuChbD/6TdyUhcQfRlSUmM1yEQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P62191	uniprotkb:Q83C21	intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|uniprotkb:Q6NW36|uniprotkb:B4DR63|ensembl:ENSP00000261303.8	intact:EBI-21286157	psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym)	psi-mi:q83c21_coxbu(display_long)|uniprotkb:CBU_1314(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286169|imex:IM-26899-37	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002793.2|ensembl:ENSG00000100764.14(gene)|ensembl:ENST00000261303.13(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|refseq:NP_001317141.1|refseq:XP_016876959.1|panther:PTHR23073(orthology-group)"	mint:Q83C21|refseq:NP_820305.2|refseq:WP_010958144.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606	rogid:DIFe5BH2MWRB3uuIhKXumw9z8+w227377	intact-crc:6192917C9E10F9A2|rigid:aUpbIu5iSAzRA0heiLW6jgEWi3Y	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9P2E3	uniprotkb:Q83D09	intact:EBI-308745|uniprotkb:Q9BQM7|uniprotkb:Q9BQM8|uniprotkb:Q9H8C1|uniprotkb:Q9H9S2|uniprotkb:Q9NUM1|uniprotkb:Q9NWW1|ensembl:ENSP00000360817.1|ensembl:ENSP00000379412.1	intact:EBI-21285965	psi-mi:znfx1_human(display_long)|uniprotkb:ZNFX1(gene name)|psi-mi:ZNFX1(display_short)|uniprotkb:KIAA1404(gene name synonym)	psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286151|imex:IM-26899-475	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066363.1|ensembl:ENSG00000124201.15(gene)|ensembl:ENST00000371752.5(transcript)|ensembl:ENST00000396105.6(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0031380""(nuclear RNA-directed RNA polymerase complex)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0051607""(defense response to virus)|interpro:IPR000967(Zinc finger, NF-X1-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|interpro:IPR045055|interpro:IPR046439|interpro:IPR047187|mint:Q9P2E3|refseq:XP_006723899.1|panther:PTHR10887(orthology-group)"	mint:Q83D09|refseq:NP_819950.2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:2vNUbYE3//YGh0eabKbzldLESF49606	rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377	intact-crc:6047374AC7316AB9|rigid:QdwKX7hrIYYXf3tqMwFUAQIe6Kg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P25788	uniprotkb:Q83C21	intact:EBI-348380|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6|ensembl:ENSP00000216455.4	intact:EBI-21286157	psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym)|uniprotkb:Proteasome subunit alpha-7(gene name synonym)	psi-mi:q83c21_coxbu(display_long)|uniprotkb:CBU_1314(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286163|imex:IM-26899-151	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567.13(gene)|ensembl:ENST00000216455.9(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019773""(proteasome core complex, alpha-subunit complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045202""(synapse)|go:""GO:0052548""(regulation of endopeptidase activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR050115|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7E55|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM3|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29366N|panther:PTHR11599(orthology-group)"	mint:Q83C21|refseq:NP_820305.2|refseq:WP_010958144.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/05	rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606	rogid:DIFe5BH2MWRB3uuIhKXumw9z8+w227377	intact-crc:E77CDA0918D8CB10|rigid:Fe0xPj6fhFmTl++WO3hixYlIiyQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O14818	uniprotkb:Q83BF4	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|ensembl:ENSP00000359910.4|uniprotkb:Q5JXJ2	intact:EBI-21286294	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)|uniprotkb:Proteasome subunit alpha-4(gene name synonym)	psi-mi:q83bf4_coxbu(display_long)|uniprotkb:CBU_1556(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286301|imex:IM-26899-377	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002783.1|ensembl:ENSG00000101182.15(gene)|ensembl:ENST00000370873.9(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019773""(proteasome core complex, alpha-subunit complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR050115|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM3|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29363N|panther:PTHR11599(orthology-group)"	"mint:Q83BF4|go:""GO:0016020""(membrane)|refseq:NP_820539.1|refseq:WP_010958299.1"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/05	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	rogid:FPvBIpxYSACDYC5jEm0L73i9Pfs227377	intact-crc:B57D806BDE1047D3|rigid:11523wBLtCtYbQmaJ8bAbeTMvyo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75976	uniprotkb:Q83BP6	intact:EBI-3916308|uniprotkb:B7Z7T9|uniprotkb:B7ZAU4|uniprotkb:F5GZH6|uniprotkb:Q86SH9|uniprotkb:O15377|uniprotkb:Q86XE6|ensembl:ENSP00000225719.4	intact:EBI-21286233	psi-mi:cbpd_human(display_long)|uniprotkb:CPD(gene name)|psi-mi:CPD(display_short)|uniprotkb:Metallocarboxypeptidase D(gene name synonym)|uniprotkb:gp180(gene name synonym)	psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286246|imex:IM-26899-479	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001295.2|refseq:NP_001186704.1|ensembl:ENSG00000108582.12(gene)|ensembl:ENST00000225719.9(transcript)|go:""GO:0004181""(metallocarboxypeptidase activity)|go:""GO:0004185""(serine-type carboxypeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006518""(peptide metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0016485""(protein processing)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR033848|interpro:IPR034224|interpro:IPR050753|mint:O75976|rcsb pdb:5AQ0|reactome:R-HSA-432722|reactome:R-HSA-9696264|reactome:R-HSA-9696273|panther:PTHR11532(orthology-group)"	mint:Q83BP6|refseq:WP_043881121.1|interpro:IPR050767|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|panther:PTHR11102(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:PC6PFm4D7KoT4utNwyIe57VUwbY9606	rogid:2oEsUhx4PQz+RmbufdyjTkr9UPM227377	intact-crc:79268E553BB51425|rigid:OwLjpJW9D9/EYTM2xInmV+GPpb4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UIJ7	uniprotkb:Q83B01	intact:EBI-3916527|ensembl:ENSP00000371230.3|uniprotkb:Q5VYW6|uniprotkb:Q9NPB4|uniprotkb:Q9H576|uniprotkb:D3DRI1|uniprotkb:Q9HC01|uniprotkb:B4DP58|uniprotkb:E7ET30	intact:EBI-21286307	psi-mi:kad3_human(display_long)|uniprotkb:AK3(gene name)|psi-mi:AK3(display_short)|uniprotkb:AK3L1(gene name synonym)|uniprotkb:AK6(gene name synonym)|uniprotkb:AKL3L(gene name synonym)|uniprotkb:Adenylate kinase 3(gene name synonym)|uniprotkb:Adenylate kinase 3 alpha-like 1(gene name synonym)|uniprotkb:Adenylate kinase isozyme 3(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286315|imex:IM-26899-581	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000147853.17(gene)|ensembl:ENST00000381809.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006172""(ADP biosynthetic process)|go:""GO:0007596""(blood coagulation)|go:""GO:0009142""(nucleoside triphosphate biosynthetic process)|go:""GO:0016874""(ligase activity)|go:""GO:0046033""(AMP metabolic process)|go:""GO:0046039""(GTP metabolic process)|go:""GO:0046041""(ITP metabolic process)|go:""GO:0046051""(UTP metabolic process)|go:""GO:0046899""(nucleoside triphosphate adenylate kinase activity)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028586|interpro:IPR033690|interpro:IPR036193|mint:Q9UIJ7|rcsb pdb:1ZD8|rcsb pdb:6ZJB|rcsb pdb:6ZJD|rcsb pdb:6ZJE|reactome:R-HSA-983231|refseq:NP_001186781.1|refseq:NP_001186782.1|refseq:NP_001186784.1|refseq:NP_001186785.1|refseq:NP_057366.2|panther:PTHR23359(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:NDt9xiBjW8L9uXYnyZhVYpVybfA9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:190F9646370C02C9|rigid:kSYNWJcKrJbUfiz+ajQ6iyKLmVM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13804	uniprotkb:Q83BP6	intact:EBI-1052886|uniprotkb:B4DT43|uniprotkb:Q53XN3|ensembl:ENSP00000452762.1|ensembl:ENSP00000510473.1	intact:EBI-21286233	psi-mi:etfa_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short)	psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286258|imex:IM-26899-253	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:394529""|efo:""Orphanet:394532""|dip:DIP-6161N|ensembl:ENSG00000140374.17(gene)|ensembl:ENST00000557943.6(transcript)|ensembl:ENST00000690610.1(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0009055""(electron transfer activity)|go:""GO:0009063""(amino acid catabolic process)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0033539""(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:""GO:0045251""(electron transfer flavoprotein complex)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR018206|interpro:IPR029035|interpro:IPR033947|mint:P13804|rcsb pdb:1EFV|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:2A1U|reactome:R-HSA-611105|refseq:NP_000117.1|refseq:NP_001121188.1|panther:PTHR43153(orthology-group)"	mint:Q83BP6|refseq:WP_043881121.1|interpro:IPR050767|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|panther:PTHR11102(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/01	rogid:J2PUTTVN+nd8eHe6TXga+37CiPw9606	rogid:2oEsUhx4PQz+RmbufdyjTkr9UPM227377	intact-crc:FD731A5A3022FB19|rigid:V5omMIdHdoJlUx0vfW29TZtUw68	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95409	uniprotkb:B5QSC8	intact:EBI-7737399|uniprotkb:Q9H309|uniprotkb:Q5VYA9|intact:MINT-2798893|ensembl:ENSP00000365514.3	intact:EBI-21286181	psi-mi:zic2_human(display_long)|uniprotkb:ZIC2(gene name)|psi-mi:ZIC2(display_short)|uniprotkb:Zinc finger protein of the cerebellum 2(gene name synonym)	psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286227|imex:IM-26899-683	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:220386""|efo:""Orphanet:280195""|efo:""Orphanet:280200""|efo:""Orphanet:93924""|efo:""Orphanet:93925""|efo:""Orphanet:93926""|ensembl:ENSG00000043355.12(gene)|ensembl:ENST00000376335.8(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007417""(central nervous system development)|go:""GO:0007420""(brain development)|go:""GO:0007601""(visual perception)|go:""GO:0016604""(nuclear body)|go:""GO:0030154""(cell differentiation)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643|interpro:IPR043359|mint:O95409|reactome:R-HSA-9823739|refseq:NP_009060.2|panther:PTHR19818(orthology-group)"	"mint:B5QSC8|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)"	-	"comment:mint|function:Involved in cerebellar development|function:""\""Defects in ZIC2 are a cause of holoprosencephaly type 5 (HPE5) [MIM:609637]. Holoprosencephaly (HPE) [MIM:236100] is the most common structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability. Although severe facial anomalies are common in HPE, patients with ZINC2 mutations have relatively normal faces\"""""	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:nap4bAVrW71xdewBlwUIcvLk/vw9606	rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377	intact-crc:56D3EDF1BD16174F|rigid:bHoiISSXKgWzjO0cMSnJsx8FwZo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P06756	uniprotkb:Q83BP6	intact:EBI-298282|uniprotkb:A0AV67|uniprotkb:Q53SK4|uniprotkb:Q59EB7|uniprotkb:Q6LD15|uniprotkb:D3DPG8|uniprotkb:B0LPF4|uniprotkb:B7Z883|uniprotkb:E7EWZ6|uniprotkb:B7ZLX0|intact:EBI-10984285|ensembl:ENSP00000261023.3	intact:EBI-21286233	psi-mi:itav_human(display_long)|uniprotkb:ITGAV(gene name)|psi-mi:ITGAV(display_short)|uniprotkb:VNRA(gene name synonym)|uniprotkb:Vitronectin receptor subunit alpha(gene name synonym)|uniprotkb:MSK8(gene name synonym)|uniprotkb:Vitronectin receptor(gene name synonym)|uniprotkb:VTNR(gene name synonym)	psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286270|imex:IM-26899-255	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138472.1|refseq:NP_002201.1|refseq:NP_001138471.1|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035579""(specific granule membrane)|dip:DIP-31785N|ensembl:ENSG00000138448.13(gene)|ensembl:ENST00000261023.8(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001846""(opsonin binding)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002020""(protease binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005245""(voltage-gated calcium channel activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008305""(integrin complex)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010745""(negative regulation of macrophage derived foam cell differentiation)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031527""(filopodium membrane)|go:""GO:0031528""(microvillus membrane)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0032369""(negative regulation of lipid transport)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034682""(integrin alphav-beta1 complex)|go:""GO:0034683""(integrin alphav-beta3 complex)|go:""GO:0034684""(integrin alphav-beta5 complex)|go:""GO:0034685""(integrin alphav-beta6 complex)|go:""GO:0034686""(integrin alphav-beta8 complex)|go:""GO:0035866""(alphav-beta3 integrin-PKCalpha complex)|go:""GO:0035867""(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:""GO:0035868""(alphav-beta3 integrin-HMGB1 complex)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050748""(negative regulation of lipoprotein metabolic process)|go:""GO:0050764""(regulation of phagocytosis)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051057""(positive regulation of small GTPase mediated signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0071604""(transforming growth factor beta production)|go:""GO:0085017""(entry into host cell by a symbiont-containing vacuole)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|go:""GO:1905598""(negative regulation of low-density lipoprotein receptor activity)|go:""GO:1990430""(extracellular matrix protein binding)|go:""GO:2000536""(negative regulation of entry of bacterium into host cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR048285|interpro:IPR048286|mint:P06756|rcsb pdb:1JV2|rcsb pdb:1L5G|rcsb pdb:1M1X|rcsb pdb:1U8C|rcsb pdb:3IJE|rcsb pdb:4G1E|rcsb pdb:4G1M|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4O02|rcsb pdb:4UM8|rcsb pdb:4UM9|rcsb pdb:5FFG|rcsb pdb:5FFO|rcsb pdb:5NEM|rcsb pdb:5NER|rcsb pdb:5NET|rcsb pdb:5NEU|rcsb pdb:6AVQ|rcsb pdb:6AVR|rcsb pdb:6AVU|rcsb pdb:6DJP|rcsb pdb:6MK0|rcsb pdb:6MSL|rcsb pdb:6MSU|rcsb pdb:6NAJ|rcsb pdb:6OM1|rcsb pdb:6OM2|rcsb pdb:6UJA|rcsb pdb:6UJB|rcsb pdb:6UJC|rcsb pdb:7Y1T|rcsb pdb:8IJ5|rcsb pdb:8TCF|rcsb pdb:8TCG|rcsb pdb:8VS6|rcsb pdb:8VSD|reactome:R-HSA-1236973|reactome:R-HSA-1566948|reactome:R-HSA-210990|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-9860927|panther:PTHR23220(orthology-group)"	mint:Q83BP6|refseq:WP_043881121.1|interpro:IPR050767|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|panther:PTHR11102(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/28	rogid:3XbANVuHd/2LJX6zckEV6xx09mY9606	rogid:2oEsUhx4PQz+RmbufdyjTkr9UPM227377	intact-crc:3292985F87B663F7|rigid:vmnKKW7vsjPlrjxF184vHk2acMw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q08211	uniprotkb:Q83BP6	intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520.3	intact:EBI-21286233	psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym)	psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286252|imex:IM-26899-771	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001348.2|dip:DIP-31504N|ensembl:ENSG00000135829.17(gene)|ensembl:ENST00000367549.4(transcript)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001069""(regulatory region RNA binding)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005726""(perichromatin fibrils)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010501""(obsolete RNA secondary structure unwinding)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016442""(RISC complex)|go:""GO:0016604""(nuclear body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017111""(ribonucleoside triphosphate phosphatase activity)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0032741""(positive regulation of interleukin-18 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033679""(3'-5' DNA/RNA helicase activity)|go:""GO:0034458""(3'-5' RNA helicase activity)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035197""(siRNA binding)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0039695""(DNA-templated viral transcription)|go:""GO:0043022""(ribosome binding)|go:""GO:0043138""(3'-5' DNA helicase activity)|go:""GO:0044806""(obsolete G-quadruplex DNA unwinding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045142""(triplex DNA binding)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046833""(positive regulation of RNA export from nucleus)|go:""GO:0046872""(metal ion binding)|go:""GO:0047429""(nucleoside triphosphate diphosphatase activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048511""(rhythmic process)|go:""GO:0050434""(positive regulation of viral transcription)|go:""GO:0050684""(regulation of mRNA processing)|go:""GO:0050691""(regulation of defense response to virus by host)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051028""(mRNA transport)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060760""(positive regulation of response to cytokine stimulus)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070578""(RISC-loading complex)|go:""GO:0070922""(RISC complex assembly)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0070937""(CRD-mediated mRNA stability complex)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071360""(cellular response to exogenous dsRNA)|go:""GO:0097165""(nuclear stress granule)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1905172""(RISC complex binding)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|go:""GO:1990825""(sequence-specific mRNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|go:""GO:2000765""(regulation of cytoplasmic translation)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|interpro:IPR048333|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|rcsb pdb:8SZP|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|reactome:R-HSA-9833482|panther:PTHR18934(orthology-group)"	mint:Q83BP6|refseq:WP_043881121.1|interpro:IPR050767|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|panther:PTHR11102(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/28	rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606	rogid:2oEsUhx4PQz+RmbufdyjTkr9UPM227377	intact-crc:3E64D3011509F3A7|rigid:OBLJDF6fPW+f33IB93XiSzZtvmA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02458	uniprotkb:Q83BP6	intact:EBI-2431412|uniprotkb:A6NGA0|uniprotkb:Q14047|uniprotkb:Q14056|uniprotkb:Q14058|uniprotkb:Q16672|uniprotkb:Q1JQ82|uniprotkb:Q12985|uniprotkb:Q14009|uniprotkb:Q14044|uniprotkb:Q14045|uniprotkb:Q14046|uniprotkb:Q9UE41|uniprotkb:Q9UE42|uniprotkb:Q9UE43|uniprotkb:Q6LBY2|uniprotkb:Q6LBY3|uniprotkb:Q96IT5|uniprotkb:Q99227|uniprotkb:Q9UE38|uniprotkb:Q9UE39|uniprotkb:Q9UE40|uniprotkb:Q2V4X7|uniprotkb:Q6LBY1|ensembl:ENSP00000369889.3	intact:EBI-21286233	psi-mi:co2a1_human(display_long)|uniprotkb:COL2A1(gene name)|psi-mi:COL2A1(display_short)|uniprotkb:Alpha-1 type II collagen(gene name synonym)	psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286240|imex:IM-26899-155	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000139219.19(gene)|ensembl:ENST00000380518.8(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001502""(cartilage condensation)|go:""GO:0001894""(tissue homeostasis)|go:""GO:0001958""(endochondral ossification)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0005576""(extracellular region)|go:""GO:0005585""(collagen type II trimer)|go:""GO:0005592""(collagen type XI trimer)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006029""(proteoglycan metabolic process)|go:""GO:0007417""(central nervous system development)|go:""GO:0007601""(visual perception)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030903""(notochord development)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042472""(inner ear morphogenesis)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0051216""(cartilage development)|go:""GO:0060021""(roof of mouth development)|go:""GO:0060174""(limb bud formation)|go:""GO:0060272""(embryonic skeletal joint morphogenesis)|go:""GO:0060351""(cartilage development involved in endochondral bone morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071599""(otic vesicle development)|go:""GO:0071773""(cellular response to BMP stimulus)|go:""GO:0097065""(anterior head development)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|mint:P02458|rcsb pdb:1U5M|rcsb pdb:2FSE|rcsb pdb:2SEB|rcsb pdb:5NIR|rcsb pdb:5OCX|rcsb pdb:5OCY|rcsb pdb:6BIN|rcsb pdb:6HG7|rcsb pdb:6NIX|rcsb pdb:7NZE|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_001835.3|refseq:NP_149162.2|efo:""Orphanet:137678""|efo:""Orphanet:166100""|efo:""Orphanet:1856""|efo:""Orphanet:209867""|efo:""Orphanet:2380""|efo:""Orphanet:459051""|efo:""Orphanet:485""|efo:""Orphanet:85166""|efo:""Orphanet:85198""|efo:""Orphanet:86820""|efo:""Orphanet:90653""|efo:""Orphanet:93279""|efo:""Orphanet:93296""|efo:""Orphanet:93297""|efo:""Orphanet:93315""|efo:""Orphanet:93316""|efo:""Orphanet:93346""|efo:""Orphanet:94068""|panther:PTHR24023(orthology-group)"	mint:Q83BP6|refseq:WP_043881121.1|interpro:IPR050767|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|panther:PTHR11102(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:T3mQ7b4d6vjE0vl3Kaa09PdldN89606	rogid:2oEsUhx4PQz+RmbufdyjTkr9UPM227377	intact-crc:0FE9CD13114B4860|rigid:NguyLIqfkgQd2GDVUDtw7TN9orw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8NCW5	uniprotkb:Q83B01	intact:EBI-2564619|uniprotkb:B4DGY3|uniprotkb:Q496C6|uniprotkb:Q5T3I2|ensembl:ENSP00000357218.3|ensembl:ENSP00000505349.1|ensembl:ENSP00000505899.1|ensembl:ENSP00000505913.1|ensembl:ENSP00000506192.1|ensembl:ENSP00000506275.1	intact:EBI-21286307	"psi-mi:nnre_human(display_long)|uniprotkb:NAXE(gene name)|psi-mi:NAXE(display_short)|uniprotkb:AIBP(gene name synonym)|uniprotkb:APOA1BP(gene name synonym)|uniprotkb:Apolipoprotein A-I-binding protein(gene name synonym)|uniprotkb:""NAD(P)HX epimerase""(gene name synonym)|uniprotkb:YJEFN1(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 1(gene name synonym)"	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286321|imex:IM-26899-379	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000163382.13(gene)|ensembl:ENST00000368235.8(transcript)|ensembl:ENST00000679702.1(transcript)|ensembl:ENST00000680004.1(transcript)|ensembl:ENST00000680269.1(transcript)|ensembl:ENST00000681054.1(transcript)|ensembl:ENST00000681523.1(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006869""(lipid transport)|go:""GO:0010874""(regulation of cholesterol efflux)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0031580""(membrane raft distribution)|go:""GO:0042802""(identical protein binding)|go:""GO:0044297""(cell body)|go:""GO:0046496""(nicotinamide nucleotide metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0052856""(""NAD(P)HX epimerase activity"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0110051""(metabolite repair)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR032976|interpro:IPR036652|mint:Q8NCW5|reactome:R-HSA-197264|refseq:NP_658985.2|efo:""Orphanet:555407""|panther:PTHR13232(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:Sbye6Tfjl+zVbAgoFH2zdfqe3709606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:0DE371FDBD9B7368|rigid:7l1sDHaF59xQ8pdpzVoyZhcM6F8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43451	uniprotkb:Q83BP6	intact:EBI-2829774|uniprotkb:Q86UM5|uniprotkb:Q75ME7|uniprotkb:Q0VAX6|ensembl:ENSP00000417515.2|uniprotkb:E7ER45	intact:EBI-21286233	psi-mi:mga_human(display_long)|uniprotkb:MGAM(gene name)|psi-mi:MGAM(display_short)|uniprotkb:MGA(gene name synonym)|uniprotkb:MGAML(gene name synonym)|uniprotkb:Alpha-1,4-glucosidase(gene name synonym)	psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286276|imex:IM-26899-775	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004659.2|ensembl:ENSG00000257335.8(gene)|ensembl:ENST00000475668.6(transcript)|go:""GO:0000025""(maltose catabolic process)|go:""GO:0003824""(catalytic activity)|go:""GO:0004339""(glucan 1,4-alpha-glucosidase activity)|go:""GO:0004558""(alpha-1,4-glucosidase activity)|go:""GO:0004574""(oligo-1,6-glucosidase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005983""(starch catabolic process)|go:""GO:0016160""(amylase activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901027""(dextrin catabolic process)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR000519(P-type trefoil)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017957|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|interpro:IPR044913|interpro:IPR048395|mint:O43451|rcsb pdb:2QLY|rcsb pdb:2QMJ|rcsb pdb:3CTT|rcsb pdb:3L4T|rcsb pdb:3L4U|rcsb pdb:3L4V|rcsb pdb:3L4W|rcsb pdb:3L4X|rcsb pdb:3L4Y|rcsb pdb:3L4Z|rcsb pdb:3TON|rcsb pdb:3TOP|reactome:R-HSA-189085|reactome:R-HSA-6798695|refseq:XP_011514974.1|refseq:XP_011514975.1|refseq:XP_016868261.1|refseq:XP_011514973.1|refseq:XP_006716231.1|refseq:XP_011514972.1|panther:PTHR22762(orthology-group)"	mint:Q83BP6|refseq:WP_043881121.1|interpro:IPR050767|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|panther:PTHR11102(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:YHyyyj0ELDf6xmuOts5HJUEpkR89606	rogid:2oEsUhx4PQz+RmbufdyjTkr9UPM227377	intact-crc:2EC9C18169104984|rigid:ix7kPyNAraNO/2QnGWUcDlM8Bhw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75368	uniprotkb:Q83BP6	intact:EBI-2854777|uniprotkb:Q5JT50|uniprotkb:Q3SYL1|uniprotkb:Q9H0N8|uniprotkb:Q6FIE8|ensembl:ENSP00000362308.5	intact:EBI-21286233	psi-mi:sh3l1_human(display_long)|uniprotkb:SH3BGRL(gene name)|psi-mi:SH3BGRL(display_short)|uniprotkb:SH3 domain-binding glutamic acid-rich-like protein 1(gene name synonym)	psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286282|imex:IM-26899-579	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003013.1|ensembl:ENSG00000131171.13(gene)|ensembl:ENST00000373212.6(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140517""(protein-RNA adaptor activity)|go:""GO:1904690""(positive regulation of cytoplasmic translational initiation)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR006993(SH3-binding, glutamic acid-rich protein)|interpro:IPR036249|interpro:IPR051033|mint:O75368|rcsb pdb:1U6T|rcsb pdb:1WRY|panther:PTHR12232(orthology-group)"	mint:Q83BP6|refseq:WP_043881121.1|interpro:IPR050767|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|panther:PTHR11102(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:28tq7yUUsqq+eH3MIo4DoDo/UlA9606	rogid:2oEsUhx4PQz+RmbufdyjTkr9UPM227377	intact-crc:71165CA4BCB597BB|rigid:w/8aIIZHsfntw2vjchqnTrAsFnk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NUM4	uniprotkb:Q83BP6	intact:EBI-10490807|uniprotkb:Q53FL9|uniprotkb:A4D108|uniprotkb:Q8N4L0|ensembl:ENSP00000379901.2|ensembl:ENSP00000379902.3|ensembl:ENSP00000401302.2|ensembl:ENSP00000515905.1	intact:EBI-21286233	psi-mi:t106b_human(display_long)|uniprotkb:TMEM106B(gene name)|psi-mi:TMEM106B(display_short)	psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286288|imex:IM-26899-481	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106460.20(gene)|ensembl:ENST00000396667.7(transcript)|ensembl:ENST00000396668.8(transcript)|ensembl:ENST00000444443.6(transcript)|ensembl:ENST00000704455.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0007040""(lysosome organization)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032418""(lysosome localization)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0051117""(ATPase binding)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:1900006""(positive regulation of dendrite development)|go:""GO:1905146""(lysosomal protein catabolic process)|go:""GO:1905671""(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)|interpro:IPR048509|interpro:IPR048511|mint:Q9NUM4|rcsb pdb:7QVC|rcsb pdb:7QVF|rcsb pdb:7QWG|rcsb pdb:7QWL|rcsb pdb:7QWM|rcsb pdb:7SAQ|rcsb pdb:7SAR|rcsb pdb:7SAS|rcsb pdb:7TMC|rcsb pdb:7U10|rcsb pdb:7U11|rcsb pdb:7U12|rcsb pdb:7U13|rcsb pdb:7U14|rcsb pdb:7U15|rcsb pdb:7U16|rcsb pdb:7U17|rcsb pdb:7U18|rcsb pdb:7X83|rcsb pdb:7X84|rcsb pdb:8B7D|rcsb pdb:8F9K|rcsb pdb:8J7N|rcsb pdb:8J7P|rcsb pdb:8OTD|rcsb pdb:8OTE|refseq:NP_001127704.1|refseq:NP_060844.2|refseq:XP_005249846.1|efo:""Orphanet:100070""|efo:""Orphanet:100069""|efo:""Orphanet:275864""|ensembl:ENSP00000379901.2|ensembl:ENSP00000379902.3|ensembl:ENSP00000401302.2|ensembl:ENSP00000515905.1|panther:PTHR28556(orthology-group)"	mint:Q83BP6|refseq:WP_043881121.1|interpro:IPR050767|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|panther:PTHR11102(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:RdOP7hFA+H8Tjb/iLZrdShpfJmg9606	rogid:2oEsUhx4PQz+RmbufdyjTkr9UPM227377	intact-crc:952C17E9E0F484C8|rigid:cCpdtZdSWeTRAl3sox4+t5bfY/0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8N128	uniprotkb:Q83BP6	intact:EBI-11043819|uniprotkb:Q68CT2|ensembl:ENSP00000371843.3|ensembl:ENSP00000451508.2|ensembl:ENSP00000514409.1|ensembl:ENSP00000514410.1	intact:EBI-21286233	psi-mi:f177a_human(display_long)|uniprotkb:FAM177A1(gene name)|psi-mi:FAM177A1(display_short)|uniprotkb:C14orf24(gene name synonym)	psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286264|imex:IM-26899-773	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001072987.1|refseq:NP_001275951.1|refseq:NP_775878.2|ensembl:ENSG00000151327.14(gene)|ensembl:ENST00000382406.7(transcript)|ensembl:ENST00000555211.6(transcript)|ensembl:ENST00000699514.1(transcript)|ensembl:ENST00000699515.1(transcript)|interpro:IPR028260|mint:Q8N128|panther:PTHR31206(orthology-group)	mint:Q83BP6|refseq:WP_043881121.1|interpro:IPR050767|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|panther:PTHR11102(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:DFER5JEcKi3kORvFi+DLZ3Ec2PQ9606	rogid:2oEsUhx4PQz+RmbufdyjTkr9UPM227377	intact-crc:372B5880BE72F134|rigid:kBvA/Wh8r6YnluikstlTX2Xe0GE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9C005	uniprotkb:Q83B01	intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066.3|ensembl:ENSP00000345837.5	intact:EBI-21286307	psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286357|imex:IM-26899-39	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115963.1|refseq:NP_001308138.1|dip:DIP-34476N|ensembl:ENSG00000162961.14(gene)|ensembl:ENST00000295066.3(transcript)|ensembl:ENST00000342166.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0016197""(endosomal transport)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0071339""(MLL1 complex)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|interpro:IPR049629|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|rcsb pdb:7UD5|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:E45EA0D8274F65E4|rigid:s9gxxhJuj77qftnrAmhYHJTyUrs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P40227	uniprotkb:Q83B01	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|intact:EBI-5912031|uniprotkb:A6NCD2|ensembl:ENSP00000275603.4|intact:EBI-26518976	intact:EBI-21286307	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 6A(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286327|imex:IM-26899-157	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11353(orthology-group)|refseq:NP_001753.1|refseq:NP_001009186.1|ensembl:ENSG00000146731.11(gene)|ensembl:ENST00000275603.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071987""(WD40-repeat domain binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904851""(positive regulation of establishment of protein localization to telomere)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR053374|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7TUB|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHD|rcsb pdb:8SHE|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|dip:DIP-33558N"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/26	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:8CFE64D9E16D7968|rigid:XoTQmkiORfo1/84wC7Fk1f/OnxI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BWU1	uniprotkb:Q83B01	intact:EBI-394593|uniprotkb:Q5JQZ7|uniprotkb:Q5JR00|uniprotkb:Q8TC78|uniprotkb:Q9UPX2|intact:EBI-28987871|ensembl:ENSP00000357907.3	intact:EBI-21286307	psi-mi:cdk19_human(display_long)|uniprotkb:CDK19(gene name)|psi-mi:CDK19(display_short)|uniprotkb:CDC2-related protein kinase 6(gene name synonym)|uniprotkb:Death-preventing kinase(gene name synonym)|uniprotkb:Cyclin-dependent kinase 11(gene name synonym)|uniprotkb:CDK11(gene name synonym)|uniprotkb:KIAA1028(gene name synonym)|uniprotkb:CDC2L6(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 6(gene name synonym)|uniprotkb:Cell division protein kinase 19(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286333|imex:IM-26899-381	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24056(orthology-group)|ensembl:ENSG00000155111.15(gene)|ensembl:ENST00000368911.8(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004693""(cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1990508""(CKM complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050108|mint:Q9BWU1|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110|refseq:NP_001287889.1|refseq:NP_001287892.1|refseq:NP_001287893.1|refseq:NP_055891.1|efo:""Orphanet:442835""|dip:DIP-29013N"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/17	rogid:80Ngzl9uqRnqMjGnO5v7j72eY7E9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:E33286BA5F66D7F7|rigid:Lewodt4NYLOlyzuzbJewc3XRDtE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q0VDF9	uniprotkb:Q83B01	intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623.3	intact:EBI-21286307	psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym)|uniprotkb:Heat shock protein family A member 14(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286369|imex:IM-26899-483	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057383.2|ensembl:ENSG00000187522.16(gene)|ensembl:ENST00000378372.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N|panther:PTHR19375(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/05	rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:44BF09F2A0322AF6|rigid:FWVbS9yMvt6dQY1NN+DxLig0E6Q	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBP4	uniprotkb:Q83B01	intact:EBI-954409|uniprotkb:Q9ULB7|uniprotkb:A8K1I2|uniprotkb:D3DQW1|ensembl:ENSP00000314910.4|ensembl:ENSP00000379762.2|ensembl:ENSP00000506835.1	intact:EBI-21286307	psi-mi:dkk3_human(display_long)|uniprotkb:REIC(gene name synonym)|uniprotkb:UNQ258/PRO295(orf name)|uniprotkb:DKK3(gene name)|psi-mi:DKK3(display_short)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286351|imex:IM-26899-383	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001018067.1|refseq:NP_037385.2|refseq:NP_056965.3|refseq:XP_006718241.1|refseq:NP_001317149.1|ensembl:ENSG00000050165.19(gene)|ensembl:ENST00000326932.8(transcript)|ensembl:ENST00000396505.7(transcript)|ensembl:ENST00000683431.1(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030325""(adrenal gland development)|go:""GO:0032348""(negative regulation of aldosterone biosynthetic process)|go:""GO:0039706""(co-receptor binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048019""(receptor antagonist activity)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1902613""(negative regulation of anti-Mullerian hormone signaling pathway)|go:""GO:2000065""(negative regulation of cortisol biosynthetic process)|interpro:IPR006796(Dickkopf, N-terminal cysteine-rich)|interpro:IPR039863|interpro:IPR047300|interpro:IPR047301|mint:Q9UBP4|panther:PTHR12113(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:pnbEZP5fAWw3Qxg1gB1sjP0Oyeo9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:AFC646AB243F4CE3|rigid:iTJLNNhnsXsWJWxA0SJo2IMGk30	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHY8	uniprotkb:Q83B01	intact:EBI-396453|uniprotkb:Q76LN0|uniprotkb:Q99690|uniprotkb:Q5EBN3|ensembl:ENSP00000385112.3|intact:EBI-28984869	intact:EBI-21286307	psi-mi:fez2_human(display_long)|uniprotkb:FEZ2(gene name)|psi-mi:FEZ2(display_short)|uniprotkb:Zygin-2(gene name synonym)|uniprotkb:Zygin II(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286363|imex:IM-26899-161	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001036013.1|refseq:NP_005093.2|ensembl:ENSG00000171055.15(gene)|ensembl:ENST00000405912.8(transcript)|go:""GO:0005737""(cytoplasm)|mint:Q9UHY8|go:""GO:0007165""(signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0007411""(axon guidance)|go:""GO:0030424""(axon)|go:""GO:1902902""(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|panther:PTHR12394(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:n5uH+vdgrrvmI+PYkcMUEnAzxwE9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:899C24BEEE295180|rigid:Cw2SYO6AqdYhgFWF8z0WDgLcqEI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14562	uniprotkb:Q83B01	intact:EBI-2511477|ensembl:ENSP00000262415.2|ensembl:ENSP00000496923.1	intact:EBI-21286307	psi-mi:dhx8_human(display_long)|uniprotkb:DHX8(gene name)|psi-mi:DHX8(display_short)|uniprotkb:DDX8(gene name synonym)|uniprotkb:DEAH box protein 8(gene name synonym)|uniprotkb:RNA helicase HRH1(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286345|imex:IM-26899-159	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000067596.12(gene)|ensembl:ENST00000262415.8(transcript)|ensembl:ENST00000650571.1(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0008380""(RNA splicing)|go:""GO:0016604""(nuclear body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR003029(S1, RNA binding)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044762|interpro:IPR048333|interpro:IPR049588|interpro:IPR049621|mint:Q14562|rcsb pdb:2EQS|rcsb pdb:3I4U|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:6HYS|rcsb pdb:6HYT|rcsb pdb:6HYU|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:9FMD|reactome:R-HSA-72163|refseq:NP_004932.1|refseq:NP_001289552.1|panther:PTHR18934(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ZUmh+KApFNV5NKCq6dizDgnw/Dw9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:976437FFA42B4C17|rigid:9YBxwe3yUftBuztZR3DQVvIQPMI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13616	uniprotkb:Q83B01	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804.3|ensembl:ENSP00000387160.1|ensembl:ENSP00000473318.1|ensembl:ENSP00000499255.1|ensembl:ENSP00000499277.1|ensembl:ENSP00000499398.1	intact:EBI-21286307	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286339|imex:IM-26899-583	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003583.2|refseq:XP_005250117.1|ensembl:ENSG00000055130.18(gene)|ensembl:ENST00000325222.9(transcript)|ensembl:ENST00000409469.5(transcript)|ensembl:ENST00000602748.5(transcript)|ensembl:ENST00000662716.1(transcript)|ensembl:ENST00000663044.1(transcript)|ensembl:ENST00000665936.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019005""(SCF ubiquitin ligase complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031146""(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0031461""(cullin-RING ubiquitin ligase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0160072""(ubiquitin ligase complex scaffold activity)|go:""GO:1990452""(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|interpro:IPR045093|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|rcsb pdb:7Z8R|rcsb pdb:7Z8T|rcsb pdb:7Z8V|rcsb pdb:7ZBW|rcsb pdb:7ZBZ|rcsb pdb:8CAF|rcsb pdb:8CDJ|rcsb pdb:8CDK|rcsb pdb:8OR0|rcsb pdb:8OR2|rcsb pdb:8OR3|rcsb pdb:8OR4|rcsb pdb:9JKB|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-9725371|reactome:R-HSA-9762114|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|dip:DIP-17013N|panther:PTHR11932(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/28	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:19A7C2BBD36912E9|rigid:/6jiFn5yNGqnkP0BZvfURoNjVC8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A5PLN9	uniprotkb:Q83B01	intact:EBI-2857298|uniprotkb:Q49A23|uniprotkb:Q4JHG0|uniprotkb:Q17RZ9|uniprotkb:Q6MZG4|uniprotkb:Q8TCM2|uniprotkb:Q9H8I3|ensembl:ENSP00000382367.3	intact:EBI-21286307	psi-mi:tpc13_human(display_long)|uniprotkb:TRAPPC13(gene name)|psi-mi:TRAPPC13(display_short)|uniprotkb:C5orf44(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286399|imex:IM-26899-685	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001087224.1|refseq:NP_001087225.1|refseq:NP_079217.2|refseq:NP_001230666.1|ensembl:ENSG00000113597.19(gene)|ensembl:ENST00000399438.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006901""(vesicle coating)|go:""GO:0099022""(vesicle tethering)|go:""GO:1990071""(TRAPPII protein complex)|go:""GO:1990072""(TRAPPIII protein complex)|interpro:IPR010378(Protein of unknown function DUF974)|mint:A5PLN9|reactome:R-HSA-8876198|dip:DIP-48284N|panther:PTHR13134(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:av9WiddXfzAIr65RDo2AXQfWtVk9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:C7B7545A323A2A05|rigid:Hoiyp0ZUuIzQSSVlMdv6ySC0cdU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P11166	uniprotkb:Q83B01	intact:EBI-717153|uniprotkb:A8K9S6|uniprotkb:O75535|uniprotkb:Q147X2|uniprotkb:B2R620|uniprotkb:D3DPX0|uniprotkb:Q0P512|ensembl:ENSP00000416293.2	intact:EBI-21286307	psi-mi:gtr1_human(display_long)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)|uniprotkb:HepG2 glucose transporter(gene name synonym)|uniprotkb:SLC2A1(gene name)|psi-mi:SLC2A1(display_short)|uniprotkb:GLUT1(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286393|imex:IM-26899-43	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:168577""|efo:""Orphanet:1942""|efo:""Orphanet:53583""|efo:""Orphanet:64280""|efo:""Orphanet:71277""|efo:""Orphanet:86911""|efo:""Orphanet:98811""|dip:DIP-23N|ensembl:ENSG00000117394.24(gene)|ensembl:ENST00000426263.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001674""(female germ cell nucleus)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0001939""(female pronucleus)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0007417""(central nervous system development)|go:""GO:0007565""(female pregnancy)|go:""GO:0014704""(intercalated disc)|go:""GO:0015911""(long-chain fatty acid import across plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019852""(L-ascorbic acid metabolic process)|go:""GO:0019900""(kinase binding)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030018""(Z disc)|go:""GO:0030496""(midbody)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0032868""(response to insulin)|go:""GO:0033300""(dehydroascorbic acid transmembrane transporter activity)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|go:""GO:0045494""(photoreceptor cell maintenance)|go:""GO:0046323""(D-glucose import)|go:""GO:0055056""(D-glucose transmembrane transporter activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070837""(dehydroascorbic acid transport)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071474""(cellular hyperosmotic response)|go:""GO:0072562""(blood microparticle)|go:""GO:0098708""(D-glucose import across plasma membrane)|go:""GO:0098793""(presynapse)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1904016""(response to Thyroglobulin triiodothyronine)|go:""GO:1904659""(D-glucose transmembrane transport)|go:""GO:1990350""(glucose transporter complex)|interpro:IPR002439(""Glucose transporter, type 1 (GLUT1)"")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|interpro:IPR045263|mint:P11166|rcsb pdb:4PYP|rcsb pdb:5EQG|rcsb pdb:5EQH|rcsb pdb:5EQI|rcsb pdb:6THA|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-422356|reactome:R-HSA-5619043|reactome:R-HSA-5653890|refseq:NP_006507.2|panther:PTHR23503(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/10	rogid:72DLUG1CFkqcf92goIZBZ4+zuls9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:40EB0EF3FC0204B0|rigid:WY5Oc046/NVgDKeKObkfHJWbDl8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P53779	uniprotkb:Q83B01	intact:EBI-713543|uniprotkb:A6NFS3|uniprotkb:Q15707|uniprotkb:Q49AP1|uniprotkb:A6NG28|uniprotkb:B3KQ94|ensembl:ENSP00000424154.3|ensembl:ENSP00000492204.1|ensembl:ENSP00000492292.1|ensembl:ENSP00000492903.1|ensembl:ENSP00000493013.1|ensembl:ENSP00000493045.1|ensembl:ENSP00000493072.1|ensembl:ENSP00000493275.1|ensembl:ENSP00000493290.1|ensembl:ENSP00000493363.1|ensembl:ENSP00000493375.1|ensembl:ENSP00000493408.1|ensembl:ENSP00000493435.1|ensembl:ENSP00000493450.1	intact:EBI-21286307	psi-mi:mk10_human(display_long)|uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)|uniprotkb:MAP kinase p49 3F12(gene name synonym)|uniprotkb:MAPK10(gene name)|psi-mi:MAPK10(display_short)|uniprotkb:JNK3(gene name synonym)|uniprotkb:JNK3A(gene name synonym)|uniprotkb:PRKM10(gene name synonym)|uniprotkb:Stress-activated protein kinase 1b(gene name synonym)|uniprotkb:SAPK1B(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286375|imex:IM-26899-41	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2382""|ensembl:ENSG00000109339.24(gene)|ensembl:ENST00000515400.3(transcript)|ensembl:ENST00000515650.2(transcript)|ensembl:ENST00000638313.1(transcript)|ensembl:ENST00000641051.1(transcript)|ensembl:ENST00000641066.1(transcript)|ensembl:ENST00000641157.1(transcript)|ensembl:ENST00000641207.1(transcript)|ensembl:ENST00000641341.1(transcript)|ensembl:ENST00000641462.2(transcript)|ensembl:ENST00000641647.1(transcript)|ensembl:ENST00000641823.1(transcript)|ensembl:ENST00000641902.1(transcript)|ensembl:ENST00000641952.1(transcript)|ensembl:ENST00000641983.1(transcript)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004708""(MAP kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0009416""(response to light stimulus)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0048511""(rhythmic process)|go:""GO:0090398""(cellular senescence)|go:""GO:0106310""(protein serine kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR050117|mint:P53779|rcsb pdb:1JNK|rcsb pdb:1PMN|rcsb pdb:1PMU|rcsb pdb:1PMV|rcsb pdb:2B1P|rcsb pdb:2EXC|rcsb pdb:2O0U|rcsb pdb:2O2U|rcsb pdb:2OK1|rcsb pdb:2P33|rcsb pdb:2R9S|rcsb pdb:2WAJ|rcsb pdb:2ZDT|rcsb pdb:2ZDU|rcsb pdb:3CGF|rcsb pdb:3CGO|rcsb pdb:3DA6|rcsb pdb:3FI2|rcsb pdb:3FI3|rcsb pdb:3FV8|rcsb pdb:3G90|rcsb pdb:3G9L|rcsb pdb:3G9N|rcsb pdb:3KVX|rcsb pdb:3OXI|rcsb pdb:3OY1|rcsb pdb:3PTG|rcsb pdb:3RTP|rcsb pdb:3TTI|rcsb pdb:3TTJ|rcsb pdb:3V6R|rcsb pdb:3V6S|rcsb pdb:4H36|rcsb pdb:4H39|rcsb pdb:4H3B|rcsb pdb:4KKE|rcsb pdb:4KKG|rcsb pdb:4KKH|rcsb pdb:4U79|rcsb pdb:4W4V|rcsb pdb:4W4W|rcsb pdb:4W4X|rcsb pdb:4W4Y|rcsb pdb:4WHZ|rcsb pdb:4Y46|rcsb pdb:4X21|rcsb pdb:4Y5H|rcsb pdb:4Z9L|rcsb pdb:6EKD|rcsb pdb:6EMH|rcsb pdb:6EQ9|rcsb pdb:7KSI|rcsb pdb:7KSJ|rcsb pdb:7KSK|rcsb pdb:7ORE|rcsb pdb:7ORF|rcsb pdb:7S1N|rcsb pdb:7YL1|rcsb pdb:8BZP|rcsb pdb:8ENJ|rcsb pdb:8WGF|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-450341|refseq:NP_001304996.1|refseq:NP_001304997.1|refseq:NP_001304998.1|refseq:NP_002744.1|refseq:NP_620446.1|refseq:NP_620448.1|refseq:XP_005263186.1|refseq:XP_005263187.1|refseq:XP_005263192.1|refseq:XP_006714331.1|refseq:XP_011530419.1|refseq:XP_011530420.1|refseq:XP_011530422.1|refseq:XP_011530423.1|refseq:XP_016863908.1|refseq:XP_016863909.1|refseq:XP_016863910.1|refseq:XP_016863912.1|refseq:XP_016863913.1|refseq:XP_016863914.1|refseq:XP_016863915.1|refseq:XP_016863918.1|refseq:XP_016863919.1|refseq:XP_016863920.1|refseq:XP_016863921.1|dip:DIP-1015N|panther:PTHR24055(orthology-group)|ensembl:ENST00000395157.9|ensembl:ENSP00000378586.4|ensembl:ENST00000395166.6|ensembl:ENSP00000378595.1|ensembl:ENSP00000424154.3|ensembl:ENSP00000492204.1|ensembl:ENST00000638225.1|ensembl:ENSP00000491866.1|ensembl:ENSP00000492292.1|ensembl:ENST00000639175.1|ensembl:ENSP00000491160.1|ensembl:ENST00000639234.1|ensembl:ENSP00000491306.1|ensembl:ENST00000639242.1|ensembl:ENSP00000491089.1|ensembl:ENST00000640858.1|ensembl:ENSP00000491122.1|ensembl:ENST00000640970.1|ensembl:ENSP00000492231.1|ensembl:ENST00000641050.1|ensembl:ENSP00000493270.1|ensembl:ENSP00000493275.1|ensembl:ENSP00000493072.1|ensembl:ENST00000641110.1|ensembl:ENSP00000493163.1|ensembl:ENSP00000493363.1|ensembl:ENST00000641170.1|ensembl:ENSP00000493237.1|ensembl:ENSP00000493450.1|ensembl:ENST00000641274.1|ensembl:ENSP00000492929.1|ensembl:ENST00000641283.1|ensembl:ENSP00000493444.1|ensembl:ENST00000641287.1|ensembl:ENSP00000493100.1|ensembl:ENST00000641297.1|ensembl:ENSP00000493092.1|ensembl:ENSP00000493290.1|ensembl:ENST00000641391.1|ensembl:ENSP00000493008.1|ensembl:ENST00000641410.1|ensembl:ENSP00000493208.1|ensembl:ENSP00000493435.1|ensembl:ENSP00000493375.1|ensembl:ENST00000641657.1|ensembl:ENSP00000493105.1|ensembl:ENST00000641724.1|ensembl:ENSP00000493038.1|ensembl:ENST00000641737.1|ensembl:ENSP00000493177.1|ensembl:ENST00000641803.1|ensembl:ENSP00000493049.1|ensembl:ENSP00000493408.1|ensembl:ENST00000641862.1|ensembl:ENSP00000493396.1|ensembl:ENSP00000492903.1|ensembl:ENST00000641911.1|ensembl:ENSP00000493374.1|ensembl:ENST00000641943.1|ensembl:ENSP00000492941.1|ensembl:ENSP00000493013.1|ensembl:ENSP00000493045.1|ensembl:ENST00000642009.1|ensembl:ENSP00000493168.1|ensembl:ENST00000642015.1|ensembl:ENSP00000493040.1|ensembl:ENST00000642038.1|ensembl:ENSP00000492942.1|ensembl:ENST00000642103.1|ensembl:ENSP00000493001.1"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/20	rogid:dzYzsLACbyCktFnxNeBXEf02BdA9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:DC5636CA5ED3C5D1|rigid:+NdfihVfGv2hJAD3SwTEV6aPNV4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y2L5	uniprotkb:Q83B01	intact:EBI-2820056|uniprotkb:A0JP15|uniprotkb:B3KME5|uniprotkb:Q9H0L2|ensembl:ENSP00000283351.4	intact:EBI-21286307	psi-mi:tppc8_human(display_long)|uniprotkb:TRAPPC8(gene name)|psi-mi:TRAPPC8(display_short)|uniprotkb:KIAA1012(gene name synonym)|uniprotkb:Protein TRS85 homolog(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286405|imex:IM-26899-45	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055754.2|dip:DIP-48280N|ensembl:ENSG00000153339.15(gene)|ensembl:ENST00000283351.10(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0030008""(TRAPP complex)|go:""GO:0032964""(collagen biosynthetic process)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0099022""(vesicle tethering)|go:""GO:1990072""(TRAPPIII protein complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024420|mint:Q9Y2L5|reactome:R-HSA-8876198|panther:PTHR12975(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ofBTdvGAgN6zCUIydAmlZ0BpGsw9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:7E1856DABB1C58BD|rigid:dYWam1/+vpOjYbTa/WT459gGaWY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NP72	uniprotkb:Q83B01	intact:EBI-722247|uniprotkb:Q53FX8|uniprotkb:Q6FIH1|uniprotkb:B3KMC7|uniprotkb:D3DRW1|intact:EBI-2859793|uniprotkb:Q56UN9|uniprotkb:B7Z333|ensembl:ENSP00000349415.7|ensembl:ENSP00000507542.1	intact:EBI-21286307	psi-mi:rab18_human(display_long)|uniprotkb:RAB18(gene name)|psi-mi:RAB18(display_short)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286387|imex:IM-26899-163	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2510""|ensembl:ENSG00000099246.19(gene)|ensembl:ENST00000356940.11(transcript)|ensembl:ENST00000682082.1(transcript)|go:""GO:0001654""(eye development)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0007420""(brain development)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019003""(GDP binding)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0034389""(lipid droplet organization)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR025662|interpro:IPR027417|interpro:IPR050227|mint:Q9NP72|rcsb pdb:1X3S|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-8873719|reactome:R-HSA-8876198|refseq:NP_001243339.1|refseq:NP_001243340.1|refseq:NP_001243341.1|refseq:NP_001243344.1|refseq:NP_067075.1|dip:DIP-60514N|panther:PTHR24073(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:xw6DaP3FsJo34UZC/jqjJEWfSeg9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:49341F24FE9B53A5|rigid:C9x3kaxWGBg1f4y4ff056bvoIA0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43396	uniprotkb:Q83B01	intact:EBI-1048857|ensembl:ENSP00000217515.5|ensembl:ENSP00000464918.1	intact:EBI-21286307	psi-mi:txnl1_human(display_long)|uniprotkb:32 kDa thioredoxin-related protein(gene name synonym)|uniprotkb:TXNL1(gene name)|psi-mi:TXNL1(display_short)|uniprotkb:TRP32(gene name synonym)|uniprotkb:TXL(gene name synonym)|uniprotkb:TXNL(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286411|imex:IM-26899-485	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004777.1|ensembl:ENSG00000091164.13(gene)|ensembl:ENST00000217515.11(transcript)|ensembl:ENST00000590954.5(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010400(Protein of unknown function DUF1000)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR037047|mint:O43396|rcsb pdb:1GH2|rcsb pdb:1WWY|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:XP_016881582.1|panther:PTHR46115(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:v3qpLTWgZZ1f4Tz/ixVYlSPv7Ro9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:96B697171CD796A3|rigid:HDvvd31/ErzVuSKv1Gx+8dHd3L4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BYG3	uniprotkb:Q83B01	intact:EBI-2561019|uniprotkb:Q8TB66|uniprotkb:A8K788|uniprotkb:Q96ED4|ensembl:ENSP00000285814.4	intact:EBI-21286307	psi-mi:mk67i_human(display_long)|uniprotkb:NIFK(gene name)|psi-mi:NIFK(display_short)|uniprotkb:MKI67IP(gene name synonym)|uniprotkb:NOPP34(gene name synonym)|uniprotkb:Nucleolar phosphoprotein Nopp34(gene name synonym)|uniprotkb:Nucleolar protein interacting with the FHA domain of pKI-67(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286381|imex:IM-26899-585	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115766.3|rcsb pdb:8FKU|ensembl:ENSG00000155438.12(gene)|ensembl:ENST00000285814.9(transcript)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0009303""(rRNA transcription)|go:""GO:0016072""(rRNA metabolic process)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021043|interpro:IPR035979|mint:Q9BYG3|rcsb pdb:2AFF|rcsb pdb:8FKP|rcsb pdb:8FKQ|rcsb pdb:8FKR|rcsb pdb:8FKS|rcsb pdb:8FKT|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|rcsb pdb:8FKZ|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR3|dip:DIP-28134N|panther:PTHR46754(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/25	rogid:DUc8AnzFxJjbK+cTW5H83GQcf6o9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:A8739F2E93FD3AE1|rigid:iPTx8B9DOmpclAawJa4Aiht/jz8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8WVV9	uniprotkb:Q83AV9	intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625.3	intact:EBI-21286417	psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name)	psi-mi:q83av9_coxbu(display_long)|uniprotkb:CBU_1769(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286433|imex:IM-26899-777	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001136122.1|refseq:NP_612403.2|panther:PTHR15592(orthology-group)|ensembl:ENSG00000143889.16(gene)|ensembl:ENST00000449105.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006397""(mRNA processing)|go:""GO:0016020""(membrane)|go:""GO:0033120""(positive regulation of RNA splicing)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045202""(synapse)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|interpro:IPR034985|interpro:IPR034986|interpro:IPR034987|interpro:IPR035979|mint:Q8WVV9|rcsb pdb:7EVS"	"mint:Q83AV9|go:""GO:0016787""(hydrolase activity)|rcsb pdb:3TRD|refseq:NP_820749.1|refseq:WP_005770384.1|interpro:IPR029058|interpro:IPR000073(Alpha/beta hydrolase fold-1)|panther:PTHR12277(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606	rogid:6GMlP2RFT4dV4vFunFZAsH4xxhI227377	intact-crc:4157CE99F11E926F|rigid:dnc1cEvwRU+F2Baghs1fTr1bWKk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O00399	uniprotkb:Q83A33	intact:EBI-2559415|ensembl:ENSP00000221114.3|uniprotkb:B2RAC1	intact:EBI-21286457	psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286472|imex:IM-26899-47	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000104671.8(gene)|ensembl:ENST00000221114.8(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0070840""(dynein complex binding)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|refseq:NP_006562.1|panther:PTHR13072(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/28	rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:E8440BCFC991AB54|rigid:sqWORM+nQHm1D/7ovttVOd/5+x0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q86VG3	uniprotkb:Q83A33	intact:EBI-3923037|uniprotkb:Q96DD6|uniprotkb:D3DR18|ensembl:ENSP00000334848.5|ensembl:ENSP00000403937.3|ensembl:ENSP00000431374.2|ensembl:ENSP00000432685.2|ensembl:ENSP00000433407.2|ensembl:ENSP00000483671.1|ensembl:ENSP00000503448.1|ensembl:ENSP00000504720.1	intact:EBI-21286457	psi-mi:iftap_human(display_long)|uniprotkb:IFTAP(gene name)|psi-mi:IFTAP(display_short)|uniprotkb:C11orf74(gene name synonym)|uniprotkb:NWC(gene name synonym)|uniprotkb:Protein HEPIS(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286466|imex:IM-26899-487	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011518187.1|refseq:XP_006718201.1|ensembl:ENSG00000166352.18(gene)|ensembl:ENST00000334307.10(transcript)|ensembl:ENST00000446510.6(transcript)|ensembl:ENST00000530697.6(transcript)|ensembl:ENST00000531554.6(transcript)|ensembl:ENST00000532470.3(transcript)|ensembl:ENST00000617650.5(transcript)|ensembl:ENST00000676979.1(transcript)|ensembl:ENST00000678060.1(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007340""(acrosome reaction)|go:""GO:0097731""(9+0 non-motile cilium)|go:""GO:0120160""(intraciliary transport particle A binding)|interpro:IPR040028|mint:Q86VG3|refseq:NP_001263651.1|refseq:NP_001263652.1|refseq:NP_001263653.1|refseq:NP_001263654.1|refseq:NP_001263655.1|refseq:NP_001263656.1|refseq:NP_620142.2|panther:PTHR35543(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:oLcIB5xXVb7erU+hZ8Bgt//y/4A9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:2038203A05D70D3B|rigid:Z1cvvBFPc301BH7OaXgKqHVJCKo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96TA2	uniprotkb:Q83AV9	intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV9|uniprotkb:D3DRV8|uniprotkb:B4DNM1|ensembl:ENSP00000318480.3|intact:EBI-10989776	intact:EBI-21286417	psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name)	psi-mi:q83av9_coxbu(display_long)|uniprotkb:CBU_1769(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286451|imex:IM-26899-587	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136758.21(gene)|ensembl:ENST00000326799.7(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010636""(positive regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034214""(protein hexamerization)|go:""GO:0034982""(mitochondrial protein processing)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664|reactome:R-HSA-9837999|reactome:R-HSA-9840373|refseq:NP_001240795.1|refseq:NP_055078.1|refseq:NP_647473.1|efo:""Orphanet:98676""|panther:PTHR23076(orthology-group)"	"mint:Q83AV9|go:""GO:0016787""(hydrolase activity)|rcsb pdb:3TRD|refseq:NP_820749.1|refseq:WP_005770384.1|interpro:IPR029058|interpro:IPR000073(Alpha/beta hydrolase fold-1)|panther:PTHR12277(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606	rogid:6GMlP2RFT4dV4vFunFZAsH4xxhI227377	intact-crc:C62788B322380FF8|rigid:gK+3dlTv4YWMqBxSElDXsh9kJos	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UNK0	uniprotkb:Q83AV9	intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255.2	intact:EBI-21286417	psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short)	psi-mi:q83av9_coxbu(display_long)|uniprotkb:CBU_1769(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286445|imex:IM-26899-779	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004844.1|ensembl:ENSG00000170310.15(gene)|ensembl:ENST00000306357.9(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0012505""(endomembrane system)|go:""GO:0019869""(chloride channel inhibitor activity)|go:""GO:0019905""(syntaxin binding)|go:""GO:0031201""(SNARE complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048278""(vesicle docking)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|interpro:IPR045242|mint:Q9UNK0|dip:DIP-47274N|panther:PTHR19957(orthology-group)"	"mint:Q83AV9|go:""GO:0016787""(hydrolase activity)|rcsb pdb:3TRD|refseq:NP_820749.1|refseq:WP_005770384.1|interpro:IPR029058|interpro:IPR000073(Alpha/beta hydrolase fold-1)|panther:PTHR12277(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/05	rogid:jdsUOdy99aWRb94ndPtawff7z/o9606	rogid:6GMlP2RFT4dV4vFunFZAsH4xxhI227377	intact-crc:082EA5CC0A354098|rigid:DdBvFwFNzAmk9PgZZe3VDVANUTY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P42568	uniprotkb:Q83AV9	intact:EBI-716132|uniprotkb:B1AMQ2|uniprotkb:D3DRJ8|intact:EBI-749963|uniprotkb:B2R7B3|uniprotkb:B7Z755|uniprotkb:Q8IVB0|intact:EBI-11060385|ensembl:ENSP00000369695.4	intact:EBI-21286417	psi-mi:af9_human(display_long)|uniprotkb:ALL1-fused gene from chromosome 9 protein(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein(gene name synonym)|uniprotkb:YEATS domain-containing protein 3(gene name synonym)|uniprotkb:MLLT3(gene name)|psi-mi:MLLT3(display_short)|uniprotkb:AF9(gene name synonym)|uniprotkb:YEATS3(gene name synonym)	psi-mi:q83av9_coxbu(display_long)|uniprotkb:CBU_1769(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286439|imex:IM-26899-385	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-56409N|ensembl:ENSG00000171843.17(gene)|ensembl:ENST00000380338.9(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005829""(cytosol)|go:""GO:0007379""(segment specification)|go:""GO:0008023""(transcription elongation factor complex)|go:""GO:0009952""(anterior/posterior pattern specification)|go:""GO:0010467""(gene expression)|go:""GO:0042393""(histone binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070577""(lysine-acetylated histone binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0140030""(modification-dependent protein binding)|go:""GO:1902275""(regulation of chromatin organization)|go:""GO:2000035""(regulation of stem cell division)|go:""GO:2000096""(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR038704|interpro:IPR040930|interpro:IPR052790|interpro:IPR055129|mint:P42568|rcsb pdb:2LM0|rcsb pdb:2MV7|rcsb pdb:2N4Q|rcsb pdb:2NDF|rcsb pdb:2NDG|rcsb pdb:4TMP|rcsb pdb:5HJB|rcsb pdb:5HJD|rcsb pdb:5YYF|rcsb pdb:6B7G|rcsb pdb:6L5Z|rcsb pdb:6LS6|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:7EIC|rcsb pdb:7EID|rcsb pdb:7VKG|rcsb pdb:7VKH|rcsb pdb:8PJ7|rcsb pdb:8TLV|rcsb pdb:8TLW|rcsb pdb:8TLX|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|refseq:NP_001273620.1|refseq:NP_004520.2|efo:""Orphanet:402017""|panther:PTHR47827(orthology-group)"	"mint:Q83AV9|go:""GO:0016787""(hydrolase activity)|rcsb pdb:3TRD|refseq:NP_820749.1|refseq:WP_005770384.1|interpro:IPR029058|interpro:IPR000073(Alpha/beta hydrolase fold-1)|panther:PTHR12277(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/01	rogid:Z+g2iDUI+CzIrL7bMjY11hYKywQ9606	rogid:6GMlP2RFT4dV4vFunFZAsH4xxhI227377	intact-crc:0BE002C9DF52C1D5|rigid:Jw4jRKtY/dOJpF72TvKqJQ772kw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UKF6	uniprotkb:Q83AV9	intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112.3	intact:EBI-21286417	psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym)	psi-mi:q83av9_coxbu(display_long)|uniprotkb:CBU_1769(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286427|imex:IM-26899-165	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|dip:DIP-42501N|ensembl:ENSG00000119203.14(gene)|ensembl:ENST00000238112.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0004534""(5'-3' RNA exonuclease activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005847""(mRNA cleavage and polyadenylation specificity factor complex)|go:""GO:0006398""(mRNA 3'-end processing by stem-loop binding and cleavage)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0046872""(metal ion binding)|go:""GO:0180010""(co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|interpro:IPR050698|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|rcsb pdb:8T1Q|rcsb pdb:8T1R|reactome:R-HSA-159231|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_057291.1|panther:PTHR11203(orthology-group)"	"mint:Q83AV9|go:""GO:0016787""(hydrolase activity)|rcsb pdb:3TRD|refseq:NP_820749.1|refseq:WP_005770384.1|interpro:IPR029058|interpro:IPR000073(Alpha/beta hydrolase fold-1)|panther:PTHR12277(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/27	rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606	rogid:6GMlP2RFT4dV4vFunFZAsH4xxhI227377	intact-crc:6B6AC888F7E7876D|rigid:b9O1evsuniJKni/3c2y9LlanW2Q	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14240	uniprotkb:Q83A33	intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381.5	intact:EBI-21286457	psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286478|imex:IM-26899-167	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24031(orthology-group)|efo:""Orphanet:528084""|ensembl:ENSG00000156976.17(gene)|ensembl:ENST00000323963.10(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1900260""(negative regulation of RNA-dependent RNA polymerase activity)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865|refseq:NP_001958.2"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/12/30	rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:A0286DD45A8D49C6|rigid:Un1eZGeCoxsMR/JMKMjHGxk53So	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q86X45	uniprotkb:Q83A11	intact:EBI-9379658|uniprotkb:Q13648|uniprotkb:Q4G183|ensembl:ENSP00000429791.1|ensembl:ENSP00000484634.1	intact:EBI-21286600	psi-mi:daa11_human(display_long)|uniprotkb:DNAAF11(gene name)|psi-mi:DNAAF11(display_short)|uniprotkb:LRRC6(gene name synonym)|uniprotkb:LRTP(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 6(gene name synonym)|uniprotkb:Leucine-rich testis-specific protein(gene name synonym)|uniprotkb:Protein tilB homolog(gene name synonym)|uniprotkb:TSLRP(gene name synonym)|uniprotkb:Testis-specific leucine-rich repeat protein(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286661|imex:IM-26899-783	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:244""|ensembl:ENSG00000129295.10(gene)|ensembl:ENST00000519595.5(transcript)|ensembl:ENST00000620350.5(transcript)|go:""GO:0003341""(cilium movement)|go:""GO:0003351""(epithelial cilium movement involved in extracellular fluid movement)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0008584""(male gonad development)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0031514""(motile cilium)|go:""GO:0036158""(outer dynein arm assembly)|go:""GO:0036159""(inner dynein arm assembly)|go:""GO:0044458""(motile cilium assembly)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0060287""(epithelial cilium movement involved in determination of left/right asymmetry)|go:""GO:0061458""(reproductive system development)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0070286""(axonemal dynein complex assembly)|go:""GO:0090651""(apical cytoplasm)|go:""GO:0090660""(cerebrospinal fluid circulation)|go:""GO:0120229""(protein localization to motile cilium)|go:""GO:0120293""(dynein axonemal particle)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR007052(CS domain)|interpro:IPR032675|mint:Q86X45|refseq:NP_001308890.1|refseq:NP_001308891.1|refseq:NP_001308892.1|refseq:NP_001308893.1|refseq:NP_001308894.1|refseq:NP_001308895.1|refseq:NP_036604.2|panther:PTHR18849(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:+KWpDTd1pD7UAK4rVDo5We0inVw9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:FD57C4661F01B111|rigid:C5QMJe8cVqOAq86QD7CFINKZpkI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6P1N2	uniprotkb:Q83A33	intact:EBI-21285736	intact:EBI-21286457	psi-mi:q6p1n2_human(display_long)|uniprotkb:MTIF2(gene name)|psi-mi:MTIF2(display_short)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286508|imex:IM-26899-387	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR053905|mint:Q6P1N2|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|refseq:NP_001005369.1|refseq:NP_002444.2|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR044145"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:1tWvOfEeLJfg31GeKiTLztjnehU9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:A8054FE09FE5F3D1|rigid:NyhX23l9wOLxFz450p0SkgbVaXY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P17301	uniprotkb:Q83A33	intact:EBI-702960|uniprotkb:Q14595|ensembl:ENSP00000296585.5	intact:EBI-21286457	psi-mi:ita2_human(display_long)|uniprotkb:Platelet membrane glycoprotein Ia(gene name synonym)|uniprotkb:Collagen receptor(gene name synonym)|uniprotkb:VLA-2 subunit alpha(gene name synonym)|uniprotkb:CD49 antigen-like family member B(gene name synonym)|uniprotkb:ITGA2(gene name)|psi-mi:ITGA2(display_short)|uniprotkb:CD49B(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286490|imex:IM-26899-687	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:853""|ensembl:ENSG00000164171.11(gene)|ensembl:ENST00000296585.10(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002687""(positive regulation of leukocyte migration)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006929""(substrate-dependent cell migration)|go:""GO:0006971""(hypotonic response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007565""(female pregnancy)|go:""GO:0007596""(blood coagulation)|go:""GO:0008305""(integrin complex)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0014075""(response to amine)|go:""GO:0014850""(response to muscle activity)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030879""(mammary gland development)|go:""GO:0031346""(positive regulation of cell projection organization)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0033591""(response to L-ascorbic acid)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0038064""(collagen receptor activity)|go:""GO:0038065""(collagen-activated signaling pathway)|go:""GO:0043236""(laminin binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0043679""(axon terminus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045178""(basal part of cell)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045987""(positive regulation of smooth muscle contraction)|go:""GO:0046872""(metal ion binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050927""(positive regulation of positive chemotaxis)|go:""GO:0050966""(detection of mechanical stimulus involved in sensory perception of pain)|go:""GO:0051971""(positive regulation of transmission of nerve impulse)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0070365""(hepatocyte differentiation)|go:""GO:0071107""(response to parathyroid hormone)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|interpro:IPR048285|interpro:IPR048286|mint:P17301|rcsb pdb:1AOX|rcsb pdb:1DZI|rcsb pdb:1V7P|rcsb pdb:4BJ3|rcsb pdb:5HJ2|rcsb pdb:5THP|rcsb pdb:6ND8|rcsb pdb:6ND9|rcsb pdb:6NDA|rcsb pdb:6NDB|rcsb pdb:6NDC|rcsb pdb:6NDD|rcsb pdb:6NDE|rcsb pdb:6NDF|rcsb pdb:6NDG|rcsb pdb:6NDH|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-447041|reactome:R-HSA-75892|reactome:R-HSA-8874081|refseq:NP_002194.2|dip:DIP-67N|panther:PTHR23220(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/27	rogid:eT9f2vINJKqOgbGP+0BiXcVxiEs9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:093361EE2FBC3BFB|rigid:pVJOgr/dPY9p39ZY2PYBTtTtbBA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q0VDF9	uniprotkb:Q83A11	intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623.3	intact:EBI-21286600	psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym)|uniprotkb:Heat shock protein family A member 14(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286643|imex:IM-26899-595	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057383.2|ensembl:ENSG00000187522.16(gene)|ensembl:ENST00000378372.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N|panther:PTHR19375(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/05	rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:A49C7CB298007FF0|rigid:0kzJz0Zm2yCo6PT+HLT9rNx32YM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8IVG5	uniprotkb:Q83A33	intact:EBI-2855510|uniprotkb:Q2TV75|uniprotkb:Q8IWI4|uniprotkb:Q2TV71|uniprotkb:A4D1G8|uniprotkb:A0PJG8|uniprotkb:Q8N3L9|uniprotkb:Q2UZV8|uniprotkb:A0JP23|uniprotkb:Q8N875|uniprotkb:A0JP24|uniprotkb:D6W5Q6|ensembl:ENSP00000326247.4|ensembl:ENSP00000391387.2|ensembl:ENSP00000391699.2|ensembl:ENSP00000396137.2|ensembl:ENSP00000405760.1|ensembl:ENSP00000408796.1|ensembl:ENSP00000410062.2|ensembl:ENSP00000514494.1	intact:EBI-21286457	psi-mi:sam9l_human(display_long)|uniprotkb:SAMD9L(gene name)|psi-mi:SAMD9L(display_short)|uniprotkb:C7orf6(gene name synonym)|uniprotkb:DRIF2(gene name synonym)|uniprotkb:KIAA2005(gene name synonym)|uniprotkb:UEF(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286526|imex:IM-26899-391	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:631106""|efo:""Orphanet:2585""|efo:""Orphanet:619367""|ensembl:ENSG00000177409.12(gene)|ensembl:ENST00000318238.9(transcript)|ensembl:ENST00000411955.5(transcript)|ensembl:ENST00000414791.6(transcript)|ensembl:ENST00000437805.5(transcript)|ensembl:ENST00000439952.6(transcript)|ensembl:ENST00000446033.2(transcript)|ensembl:ENST00000446959.6(transcript)|ensembl:ENST00000699641.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8IVG5|refseq:NP_001290425.1|refseq:NP_001290426.1|refseq:NP_001290427.1|refseq:NP_001290429.1|refseq:NP_689916.2|refseq:XP_005250250.1|refseq:XP_006715953.1|refseq:XP_011514205.1|refseq:XP_016867311.1|refseq:XP_016867312.1|panther:PTHR16155(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:LeLNrbdYVE3Ch9qGEB0dmf24wMU9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:626675AB5DCA5BF4|rigid:u8f6iQlPvQtCaHnIXVr4OtRDaFY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q08AH3	uniprotkb:Q83A11	intact:EBI-21286556|ensembl:ENSP00000219054.6|ensembl:ENSP00000379411.2|ensembl:ENSP00000459451.1|ensembl:ENSP00000460349.1|uniprotkb:B3KTT9|uniprotkb:O75202	intact:EBI-21286600	psi-mi:acs2a_human(display_long)|uniprotkb:Benzoate--CoA ligase(gene name synonym)|uniprotkb:ACSM2A(gene name)|psi-mi:ACSM2A(display_short)|uniprotkb:ACSM2(gene name synonym)|uniprotkb:MACS2(gene name synonym)|uniprotkb:Acyl-CoA synthetase medium-chain family member 2A(gene name synonym)|uniprotkb:Butyrate--CoA ligase 2A(gene name synonym)|uniprotkb:Butyryl-coenzyme A synthetase 2A(gene name synonym)|uniprotkb:Middle-chain acyl-CoA synthetase 2A(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286607|imex:IM-26899-593	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000183747.12(gene)|ensembl:ENST00000219054.10(transcript)|ensembl:ENST00000396104.2(transcript)|ensembl:ENST00000573854.6(transcript)|ensembl:ENST00000575690.5(transcript)|go:""GO:0004321""(fatty-acyl-CoA synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0006637""(acyl-CoA metabolic process)|go:""GO:0015645""(fatty acid ligase activity)|go:""GO:0018858""(benzoate-CoA ligase activity)|go:""GO:0031956""(medium-chain fatty acid-CoA ligase activity)|go:""GO:0036112""(medium-chain fatty-acyl-CoA metabolic process)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0046872""(metal ion binding)|go:""GO:0070328""(triglyceride homeostasis)|go:""GO:0102391""(decanoate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|interpro:IPR045851|interpro:IPR051087|mint:Q08AH3|rcsb pdb:2VZE|rcsb pdb:2WD9|rcsb pdb:3B7W|rcsb pdb:3C5E|rcsb pdb:3DAY|rcsb pdb:3EQ6|rcsb pdb:3GPC|reactome:R-HSA-177128|reactome:R-HSA-9749641|refseq:NP_001295101.1|refseq:NP_001295883.1|refseq:XP_016878412.1|panther:PTHR43605(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:DwWZXd/Ir5INoGoRwyGGGasUlnw9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:E451F057F7F21BA8|rigid:Fzfe96jtU4CCjGPTJK5eZoKo9rY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHA3	uniprotkb:Q83A33	intact:EBI-749321|uniprotkb:Q561V8|uniprotkb:Q8N6S8|uniprotkb:Q96B04|uniprotkb:Q96C76|uniprotkb:Q96HJ1|uniprotkb:B2RD72|ensembl:ENSP00000260443.4	intact:EBI-21286457	psi-mi:rlp24_human(display_long)|uniprotkb:Ribosomal protein L24-like(gene name synonym)|uniprotkb:RSL24D1(gene name)|psi-mi:RSL24D1(display_short)|uniprotkb:RPL24L(gene name synonym)|uniprotkb:My024(orf name)|uniprotkb:C15orf15(gene name synonym)|uniprotkb:Ribosomal L24 domain-containing protein 1(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286520|imex:IM-26899-389	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057388.1|ensembl:ENSG00000137876.11(gene)|ensembl:ENST00000260443.9(transcript)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005840""(ribosome)|go:""GO:0006412""(translation)|go:""GO:0042273""(ribosomal large subunit biogenesis)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:Q9UHA3|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:8FKP|rcsb pdb:8FKQ|rcsb pdb:8FKR|rcsb pdb:8FKS|rcsb pdb:8FKT|rcsb pdb:8FKU|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|rcsb pdb:8FKZ|rcsb pdb:8FL0|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FL9|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLC|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8FLF|rcsb pdb:8IDT|rcsb pdb:8IDY|rcsb pdb:8IE3|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8INK|rcsb pdb:8IPD|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR1|rcsb pdb:8IR3|panther:PTHR10792(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:dP0x5J6G4bPc/7sbV1LIxLNLDn09606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:EA352F50EAA6C31D|rigid:xhEpTlWiA0tATHq0mEo4hxR00CE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13017	uniprotkb:Q83A11	intact:EBI-7237884|uniprotkb:Q05BU8|uniprotkb:Q59ER0|uniprotkb:Q6DHZ3|uniprotkb:Q05BE8|uniprotkb:D3DS90|uniprotkb:A8KAA1|intact:MINT-1191615|uniprotkb:D3DS89|uniprotkb:A1L375|uniprotkb:A1L376|ensembl:ENSP00000371897.1|ensembl:ENSP00000441692.2	intact:EBI-21286600	psi-mi:rhg05_human(display_long)|uniprotkb:ARHGAP5(gene name)|psi-mi:ARHGAP5(display_short)|uniprotkb:RHOGAP5(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 5(gene name synonym)|uniprotkb:p190-B(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286613|imex:IM-26899-491	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001164.2|refseq:NP_001025226.1|refseq:XP_005267692.1|refseq:XP_005267693.1|refseq:XP_016876776.1|refseq:XP_016876777.1|ensembl:ENSG00000100852.14(gene)|ensembl:ENST00000345122.8(transcript)|ensembl:ENST00000539826.6(transcript)|go:""GO:0002053""(positive regulation of mesenchymal cell proliferation)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008361""(regulation of cell size)|go:""GO:0010631""(epithelial cell migration)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0030879""(mammary gland development)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|interpro:IPR045786|interpro:IPR051978|mint:Q13017|rcsb pdb:2EE4|rcsb pdb:2EE5|rcsb pdb:5U4V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|panther:PTHR46005(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	function:GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of p120GAP|comment:mint|comment:homomint	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:CcK8+6n27QR+L45eRsmnJP82TQE9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:E2BC96CEB7208F90|rigid:hn0GtHDaGbe0HfuGAqWWwtVkfF0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y4Y9	uniprotkb:Q83A11	intact:EBI-373007|ensembl:ENSP00000410758.2	intact:EBI-21286600	psi-mi:lsm5_human(display_long)|uniprotkb:LSM5(gene name)|psi-mi:LSM5(display_short)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286667|imex:IM-26899-57	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR20971(orthology-group)|ensembl:ENSG00000106355.10(gene)|ensembl:ENST00000450169.7(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005688""(U6 snRNP)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0009617""(response to bacterium)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0120115""(Lsm2-8 complex)|go:""GO:1990726""(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR033871|interpro:IPR047575|mint:Q9Y4Y9|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8QO9|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RM5|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_001124182.1|refseq:NP_001132971.1|refseq:NP_036454.1|dip:DIP-31162N"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/14	rogid:EeF2r4qY+BFrZTyTCT+i4ccskf49606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:F5C4D4BAEA2A47EF|rigid:Hihiq1cO/tD+MDEvgVxrL+UxyDY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TAF3	uniprotkb:Q83A33	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491.5	intact:EBI-21286457	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286550|imex:IM-26899-591	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50841N|efo:""Orphanet:401800""|ensembl:ENSG00000114742.14(gene)|ensembl:ENST00000302313.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043588""(skin development)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:1902525""(regulation of protein monoubiquitination)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|interpro:IPR051246|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|refseq:NP_065890.1|panther:PTHR19862(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:468DB85C08492747|rigid:x8n86EoLhVAxPifCn3xVbYXUAF4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P30085	uniprotkb:Q83A11	intact:EBI-1053384|uniprotkb:Q53GB7|uniprotkb:Q5SVZ0|uniprotkb:Q96C07|uniprotkb:Q9UBQ8|uniprotkb:Q9UIA2|ensembl:ENSP00000514114.1|uniprotkb:B4DPU7|uniprotkb:E9PGI8|intact:EBI-14470672|uniprotkb:B2R6S5	intact:EBI-21286600	psi-mi:kcy_human(display_long)|uniprotkb:CMPK(gene name synonym)|uniprotkb:Deoxycytidylate kinase(gene name synonym)|uniprotkb:Uridine monophosphate/cytidine monophosphate kinase(gene name synonym)|uniprotkb:CMPK1(gene name)|psi-mi:CMPK1(display_short)|uniprotkb:CMK(gene name synonym)|uniprotkb:UCK(gene name synonym)|uniprotkb:UMK(gene name synonym)|uniprotkb:UMPK(gene name synonym)|uniprotkb:Nucleoside-diphosphate kinase(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286625|imex:IM-26899-51	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001129612.1|refseq:NP_057392.1|ensembl:ENSG00000162368.15(gene)|ensembl:ENST00000699075.1(transcript)|go:""GO:0004127""(""(d)CMP kinase activity"")|go:""GO:0004550""(nucleoside diphosphate kinase activity)|go:""GO:0004849""(uridine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006225""(UDP biosynthetic process)|go:""GO:0009220""(pyrimidine ribonucleotide biosynthetic process)|go:""GO:0015949""(nucleobase-containing small molecule interconversion)|go:""GO:0033862""(UMP kinase activity)|go:""GO:0036430""(CMP kinase activity)|go:""GO:0036431""(dCMP kinase activity)|go:""GO:0046705""(CDP biosynthetic process)|go:""GO:0050145""(nucleoside monophosphate kinase activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006266(UMP-CMP kinase)|interpro:IPR027417|interpro:IPR033690|mint:P30085|rcsb pdb:1TEV|rcsb pdb:7E9V|reactome:R-HSA-499943|panther:PTHR23359(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:NUl0+m77fVbeIbhsbRekyl45k0w9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:49DA98EEC2C8EC8E|rigid:PvHPOnB3T36+UfNXDlDFojgUE4o	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBS4	uniprotkb:Q83A11	intact:EBI-713113|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6|ensembl:ENSP00000265028.3|ensembl:ENSP00000414398.1	intact:EBI-21286600	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286631|imex:IM-26899-259	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090520.12(gene)|ensembl:ENST00000265028.8(transcript)|ensembl:ENST00000439351.5(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006457""(protein folding)|go:""GO:0016020""(membrane)|go:""GO:0016556""(mRNA modification)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051604""(protein maturation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0101031""(protein folding chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|interpro:IPR051736|mint:Q9UBS4|reactome:R-HSA-381038|refseq:NP_057390.1|efo:""Orphanet:730""|dip:DIP-29678N|panther:PTHR44298(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/01	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:46A7FE10E11AECCC|rigid:OQkxe3/2fP3AN6bNbQcMVISD8aA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H0F5	uniprotkb:Q83A33	intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748|ensembl:ENSP00000259605.6	intact:EBI-21286457	psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286514|imex:IM-26899-49	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1|ensembl:ENSG00000137075.18(gene)|ensembl:ENST00000259605.11(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008584""(male gonad development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0036126""(sperm flagellum)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:7OJX|panther:PTHR46171(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:1EAC6261C74D6FB8|rigid:BJicUcaEQyoCjLBfcjejDFmBLnk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43451	uniprotkb:Q83A33	intact:EBI-2829774|uniprotkb:Q86UM5|uniprotkb:Q75ME7|uniprotkb:Q0VAX6|ensembl:ENSP00000417515.2|uniprotkb:E7ER45	intact:EBI-21286457	psi-mi:mga_human(display_long)|uniprotkb:MGAM(gene name)|psi-mi:MGAM(display_short)|uniprotkb:MGA(gene name synonym)|uniprotkb:MGAML(gene name synonym)|uniprotkb:Alpha-1,4-glucosidase(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286502|imex:IM-26899-257	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004659.2|ensembl:ENSG00000257335.8(gene)|ensembl:ENST00000475668.6(transcript)|go:""GO:0000025""(maltose catabolic process)|go:""GO:0003824""(catalytic activity)|go:""GO:0004339""(glucan 1,4-alpha-glucosidase activity)|go:""GO:0004558""(alpha-1,4-glucosidase activity)|go:""GO:0004574""(oligo-1,6-glucosidase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005983""(starch catabolic process)|go:""GO:0016160""(amylase activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901027""(dextrin catabolic process)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR000519(P-type trefoil)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017957|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|interpro:IPR044913|interpro:IPR048395|mint:O43451|rcsb pdb:2QLY|rcsb pdb:2QMJ|rcsb pdb:3CTT|rcsb pdb:3L4T|rcsb pdb:3L4U|rcsb pdb:3L4V|rcsb pdb:3L4W|rcsb pdb:3L4X|rcsb pdb:3L4Y|rcsb pdb:3L4Z|rcsb pdb:3TON|rcsb pdb:3TOP|reactome:R-HSA-189085|reactome:R-HSA-6798695|refseq:XP_011514974.1|refseq:XP_011514975.1|refseq:XP_016868261.1|refseq:XP_011514973.1|refseq:XP_006716231.1|refseq:XP_011514972.1|panther:PTHR22762(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:YHyyyj0ELDf6xmuOts5HJUEpkR89606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:1CE758A370B05DE6|rigid:s8yus+jqDYjGBGaA2L9ybg/cTlk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P01116	uniprotkb:Q83A11	intact:EBI-367415|uniprotkb:P01118|uniprotkb:Q96D10|uniprotkb:B0LPF9|uniprotkb:A8K8Z5|ensembl:ENSP00000256078.5	intact:EBI-21286600	psi-mi:rask_human(display_long)|uniprotkb:KRAS(gene name)|psi-mi:KRAS(display_short)|uniprotkb:RASK2(gene name synonym)|uniprotkb:KRAS2(gene name synonym)|uniprotkb:K-Ras 2(gene name synonym)|uniprotkb:Ki-Ras(gene name synonym)|uniprotkb:c-K-ras(gene name synonym)|uniprotkb:c-Ki-ras(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286649|imex:IM-26899-493	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1333""|efo:""Orphanet:1340""|efo:""Orphanet:144""|efo:""Orphanet:146""|efo:""Orphanet:2396""|efo:""Orphanet:251615""|efo:""Orphanet:2612""|efo:""Orphanet:268114""|efo:""Orphanet:3339""|efo:""Orphanet:648""|efo:""Orphanet:86834""|ensembl:ENSG00000133703.14(gene)|ensembl:ENST00000256078.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0008542""(visual learning)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010467""(gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019003""(GDP binding)|go:""GO:0021897""(forebrain astrocyte development)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030857""(negative regulation of epithelial cell differentiation)|go:""GO:0032228""(regulation of synaptic transmission, GABAergic)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060441""(epithelial tube branching involved in lung morphogenesis)|go:""GO:0060509""(type I pneumocyte differentiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01116|rcsb pdb:1D8D|rcsb pdb:1D8E|rcsb pdb:1KZO|rcsb pdb:1KZP|rcsb pdb:1N4P|rcsb pdb:1N4Q|rcsb pdb:1N4R|rcsb pdb:1N4S|rcsb pdb:2MSC|rcsb pdb:2MSD|rcsb pdb:2MSE|rcsb pdb:3GFT|rcsb pdb:4DSN|rcsb pdb:4DSO|rcsb pdb:4EPR|rcsb pdb:4EPT|rcsb pdb:4EPV|rcsb pdb:4EPW|rcsb pdb:4EPX|rcsb pdb:4EPY|rcsb pdb:4L8G|rcsb pdb:4LDJ|rcsb pdb:4LPK|rcsb pdb:4LRW|rcsb pdb:4LUC|rcsb pdb:4LV6|rcsb pdb:4LYF|rcsb pdb:4LYH|rcsb pdb:4LYJ|rcsb pdb:4M1O|rcsb pdb:4M1S|rcsb pdb:4M1T|rcsb pdb:4M1W|rcsb pdb:4M1Y|rcsb pdb:4M21|rcsb pdb:4M22|rcsb pdb:4NMM|rcsb pdb:4OBE|rcsb pdb:4PZY|rcsb pdb:4PZZ|rcsb pdb:4Q01|rcsb pdb:4Q02|rcsb pdb:4Q03|rcsb pdb:4QL3|rcsb pdb:4TQ9|rcsb pdb:4TQA|rcsb pdb:4WA7|rcsb pdb:5F2E|rcsb pdb:5KYK|rcsb pdb:5MLA|rcsb pdb:5MLB|rcsb pdb:5O2S|rcsb pdb:5O2T|rcsb pdb:5OCG|rcsb pdb:5OCO|rcsb pdb:5OCT|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5UFE|rcsb pdb:5UFQ|rcsb pdb:5UK9|rcsb pdb:5UQW|rcsb pdb:5US4|rcsb pdb:5USJ|rcsb pdb:5V6S|rcsb pdb:5V6V|rcsb pdb:5V71|rcsb pdb:5V9L|rcsb pdb:5V9O|rcsb pdb:5V9U|rcsb pdb:5VBM|rcsb pdb:5VP7|rcsb pdb:5VPI|rcsb pdb:5VPY|rcsb pdb:5VPZ|rcsb pdb:5VQ0|rcsb pdb:5VQ1|rcsb pdb:5VQ2|rcsb pdb:5VQ6|rcsb pdb:5VQ8|rcsb pdb:5W22|rcsb pdb:5WHA|rcsb pdb:5WHB|rcsb pdb:5WHD|rcsb pdb:5WHE|rcsb pdb:5WLB|rcsb pdb:5WPM|rcsb pdb:5XCO|rcsb pdb:5YXZ|rcsb pdb:5YY1|rcsb pdb:6ARK|rcsb pdb:6ASA|rcsb pdb:6ASE|rcsb pdb:6B0V|rcsb pdb:6B0Y|rcsb pdb:6BOF|rcsb pdb:6BP1|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CU6|rcsb pdb:6E6F|rcsb pdb:6E6G|rcsb pdb:6EPL|rcsb pdb:6EPM|rcsb pdb:6EPN|rcsb pdb:6EPO|rcsb pdb:6EPP|rcsb pdb:6F76|rcsb pdb:6FA1|rcsb pdb:6FA2|rcsb pdb:6FA3|rcsb pdb:6FA4|rcsb pdb:6GJ5|rcsb pdb:6GJ6|rcsb pdb:6GJ7|rcsb pdb:6GJ8|rcsb pdb:6GOD|rcsb pdb:6GOE|rcsb pdb:6GOF|rcsb pdb:6GOG|rcsb pdb:6GOM|rcsb pdb:6GQT|rcsb pdb:6GQW|rcsb pdb:6GQX|rcsb pdb:6GQY|rcsb pdb:6H46|rcsb pdb:6H47|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6M9W|rcsb pdb:6MBQ|rcsb pdb:6MBT|rcsb pdb:6MBU|rcsb pdb:6MNX|rcsb pdb:6MQG|rcsb pdb:6MQN|rcsb pdb:6MS9|rcsb pdb:6MTA|rcsb pdb:6N2J|rcsb pdb:6N2K|rcsb pdb:6O36|rcsb pdb:6O46|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6OB2|rcsb pdb:6OB3|rcsb pdb:6OIM|rcsb pdb:6P0Z|rcsb pdb:6P8W|rcsb pdb:6P8X|rcsb pdb:6P8Y|rcsb pdb:6P8Z|rcsb pdb:6PGO|rcsb pdb:6PGP|rcsb pdb:6PQ3|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6QUU|rcsb pdb:6QUV|rcsb pdb:6QUW|rcsb pdb:6QUX|rcsb pdb:6T5B|rcsb pdb:6T5U|rcsb pdb:6T5V|rcsb pdb:6TAM|rcsb pdb:6TAN|rcsb pdb:6USX|rcsb pdb:6USZ|rcsb pdb:6UT0|rcsb pdb:6V5L|rcsb pdb:6V65|rcsb pdb:6V6F|rcsb pdb:6VC8|rcsb pdb:6VJJ|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:6WGN|rcsb pdb:6WS2|rcsb pdb:6WS4|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6YR8|rcsb pdb:6YXW|rcsb pdb:6ZL5|rcsb pdb:6ZLI|rcsb pdb:7A1W|rcsb pdb:7A1X|rcsb pdb:7A1Y|rcsb pdb:7A47|rcsb pdb:7ACA|rcsb pdb:7ACF|rcsb pdb:7ACH|rcsb pdb:7ACQ|rcsb pdb:7C40|rcsb pdb:7C41|rcsb pdb:7EW9|rcsb pdb:7EWA|rcsb pdb:7EWB|rcsb pdb:7EYX|rcsb pdb:7F0W|rcsb pdb:7KFZ|rcsb pdb:7KMR|rcsb pdb:7KYZ|rcsb pdb:7LC1|rcsb pdb:7LC2|rcsb pdb:7LGI|rcsb pdb:7LZ5|rcsb pdb:7MDP|rcsb pdb:7MQU|rcsb pdb:7NY8|rcsb pdb:7O70|rcsb pdb:7OK3|rcsb pdb:7OK4|rcsb pdb:7OO7|rcsb pdb:7Q9U|rcsb pdb:7R0M|rcsb pdb:7R0N|rcsb pdb:7R0Q|rcsb pdb:7ROV|rcsb pdb:7RP2|rcsb pdb:7RP3|rcsb pdb:7RP4|rcsb pdb:7RPZ|rcsb pdb:7RSC|rcsb pdb:7RSE|rcsb pdb:7RT1|rcsb pdb:7RT2|rcsb pdb:7RT3|rcsb pdb:7RT4|rcsb pdb:7RT5|rcsb pdb:7SCW|rcsb pdb:7SCX|rcsb pdb:7STF|rcsb pdb:7T1F|rcsb pdb:7T47|rcsb pdb:7TLE|rcsb pdb:7TLG|rcsb pdb:7TLK|rcsb pdb:7U8H|rcsb pdb:7VVB|rcsb pdb:7W5R|rcsb pdb:7YCC|rcsb pdb:7YCE|rcsb pdb:7YUZ|rcsb pdb:7YV1|rcsb pdb:8AFB|rcsb pdb:8AFC|rcsb pdb:8AFD|rcsb pdb:8AQ5|rcsb pdb:8AQ7|rcsb pdb:8AZR|rcsb pdb:8AZV|rcsb pdb:8AZX|rcsb pdb:8AZY|rcsb pdb:8AZZ|rcsb pdb:8B00|rcsb pdb:8B69|rcsb pdb:8B6I|rcsb pdb:8B78|rcsb pdb:8BE3|rcsb pdb:8BE4|rcsb pdb:8BE5|rcsb pdb:8BLR|rcsb pdb:8CPR|rcsb pdb:8CX5|rcsb pdb:8DGS|rcsb pdb:8DGT|rcsb pdb:8DNI|rcsb pdb:8DNJ|rcsb pdb:8DNK|rcsb pdb:8DVG|rcsb pdb:8EBZ|rcsb pdb:8ECR|rcsb pdb:8EDY|rcsb pdb:8EER|rcsb pdb:8EIE|rcsb pdb:8EPW|rcsb pdb:8EZG|rcsb pdb:8F0M|rcsb pdb:8FMI|rcsb pdb:8FMJ|rcsb pdb:8FMK|rcsb pdb:8G42|rcsb pdb:8G47|rcsb pdb:8G4F|rcsb pdb:8G4H|rcsb pdb:8G9P|rcsb pdb:8G9Q|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8JGD|rcsb pdb:8JHL|rcsb pdb:8JJS|rcsb pdb:8ONV|rcsb pdb:8PI0|rcsb pdb:8QU8|rcsb pdb:8QUG|rcsb pdb:8QVU|rcsb pdb:8QW6|rcsb pdb:8QW7|rcsb pdb:8R7W|rcsb pdb:8R7X|rcsb pdb:8S8C|rcsb pdb:8STM|rcsb pdb:8STN|rcsb pdb:8T4V|rcsb pdb:8T71|rcsb pdb:8T72|rcsb pdb:8T73|rcsb pdb:8T74|rcsb pdb:8T75|rcsb pdb:8TBF|rcsb pdb:8TBH|rcsb pdb:8TBJ|rcsb pdb:8TBK|rcsb pdb:8TBL|rcsb pdb:8TBM|rcsb pdb:8TBN|rcsb pdb:8TVK|rcsb pdb:8TXE|rcsb pdb:8TXG|rcsb pdb:8TXH|rcsb pdb:8TXJ|rcsb pdb:8TXK|rcsb pdb:8TY2|rcsb pdb:8TY8|rcsb pdb:8TY9|rcsb pdb:8UDR|rcsb pdb:8UN3|rcsb pdb:8UN4|rcsb pdb:8UN5|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8X6R|rcsb pdb:9AX6|rcsb pdb:9BFY|rcsb pdb:9BG1|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-4086398|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5658442|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-8951936|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9753510|reactome:R-HSA-9753512|refseq:NP_004976.2|refseq:NP_203524.1|refseq:XP_006719132.1|refseq:XP_011518955.1|dip:DIP-33951N|panther:PTHR24070(orthology-group)|ensembl:ENSP00000256078.5|ensembl:ENST00000311936.8|ensembl:ENSP00000308495.3|ensembl:ENST00000685328.1|ensembl:ENSP00000508921.1|ensembl:ENST00000688940.1|ensembl:ENSP00000509238.1"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ujXYEgifbSf/thk1UOTW7sKWkX89606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:B0DE63D322D475E9|rigid:0LH8uij0dSTkpW/b7qNKJzckulE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P40818	uniprotkb:Q83A33	intact:EBI-1050865|uniprotkb:Q2TB31|uniprotkb:Q7Z3U2|uniprotkb:Q86VA0|uniprotkb:Q8IWI7|uniprotkb:B4DKA8|ensembl:ENSP00000302239.4|ensembl:ENSP00000379721.3	intact:EBI-21286457	psi-mi:ubp8_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:USP8(gene name)|psi-mi:USP8(display_short)|uniprotkb:KIAA0055(gene name synonym)|uniprotkb:UBPY(gene name synonym)|uniprotkb:Ubiquitin isopeptidase Y(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286544|imex:IM-26899-393	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-40365N|ensembl:ENSG00000138592.14(gene)|ensembl:ENST00000307179.9(transcript)|ensembl:ENST00000396444.7(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007032""(endosome organization)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0010008""(endosome membrane)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030496""(midbody)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0043197""(dendritic spine)|go:""GO:0045296""(cadherin binding)|go:""GO:0061578""(K63-linked deubiquitinase activity)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099576""(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:""GO:1905166""(negative regulation of lysosomal protein catabolic process)|go:""GO:1905908""(positive regulation of amyloid fibril formation)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990380""(K48-linked deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|interpro:IPR048498|interpro:IPR050185|mint:P40818|rcsb pdb:1WHB|rcsb pdb:2A9U|rcsb pdb:2GFO|rcsb pdb:2GWF|rcsb pdb:3N3K|rcsb pdb:6F09|rcsb pdb:8ADM|rcsb pdb:8XPN|rcsb pdb:8Y9A|reactome:R-HSA-1358803|reactome:R-HSA-4641263|reactome:R-HSA-5689880|reactome:R-HSA-6807004|refseq:NP_001122082.1|refseq:NP_001269978.1|refseq:NP_005145.3|refseq:XP_006720824.1|refseq:XP_011520495.1|efo:""Orphanet:401795""|efo:""Orphanet:96253""|panther:PTHR21646(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/27	rogid:hpBBzyA4lc9is80ZFJBr1fyEyOM9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:CB78A7B0E21B3677|rigid:WtV+mmcLI21539mDxbylBGGwNf0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P06858	uniprotkb:Q83A11	intact:EBI-715909|uniprotkb:Q16282|uniprotkb:Q16283|uniprotkb:Q96FC4|uniprotkb:B2R5T9|ensembl:ENSP00000497642.1	intact:EBI-21286600	psi-mi:lipl_human(display_long)|uniprotkb:LPL(gene name)|psi-mi:LPL(display_short)|uniprotkb:LIPD(gene name synonym)|uniprotkb:Phospholipase A1(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286655|imex:IM-26899-55	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000175445.17(gene)|ensembl:ENST00000650287.1(transcript)|go:""GO:0004465""(lipoprotein lipase activity)|go:""GO:0004620""(phospholipase activity)|go:""GO:0004806""(triacylglycerol lipase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0006644""(phospholipid metabolic process)|go:""GO:0008201""(heparin binding)|go:""GO:0008970""(phospholipase A1 activity)|go:""GO:0009617""(response to bacterium)|go:""GO:0009749""(response to glucose)|go:""GO:0009986""(cell surface)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010886""(positive regulation of cholesterol storage)|go:""GO:0010890""(positive regulation of triglyceride storage)|go:""GO:0019433""(triglyceride catabolic process)|go:""GO:0031670""(cellular response to nutrient)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0034361""(very-low-density lipoprotein particle)|go:""GO:0034371""(chylomicron remodeling)|go:""GO:0034372""(very-low-density lipoprotein particle remodeling)|go:""GO:0034375""(high-density lipoprotein particle remodeling)|go:""GO:0042627""(chylomicron)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0052739""(obsolete phosphatidylserine 1-acylhydrolase activity)|go:""GO:0055096""(low-density lipoprotein particle mediated signaling)|go:""GO:0070328""(triglyceride homeostasis)|go:""GO:0071398""(cellular response to fatty acid)|go:""GO:0071813""(lipoprotein particle binding)|go:""GO:1902494""(catalytic complex)|go:""GO:1904179""(positive regulation of adipose tissue development)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|interpro:IPR000734(Lipase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR002330(Lipoprotein lipase)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR029058|interpro:IPR033906|interpro:IPR036392|mint:P06858|rcsb pdb:6E7K|rcsb pdb:6OAU|rcsb pdb:6OAZ|rcsb pdb:6OB0|rcsb pdb:6WN4|reactome:R-HSA-381340|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-9841922|refseq:NP_000228.1|efo:""Orphanet:309015""|panther:PTHR11610(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:PM82k8/f6nyAUhaTSvIUvjVkbYU9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:D0F3956662175ACB|rigid:pQnQMMnLcirG2hWGLV0SS8DnDH8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NR56	uniprotkb:Q83A33	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	intact:EBI-21286457	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286496|imex:IM-26899-489	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:DE746C403B6A24E5|rigid:3jHl2w7+yttAedsS5rm34VfVw38	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P52566	uniprotkb:Q83A11	intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945.4|ensembl:ENSP00000440560.1|ensembl:ENSP00000444860.1	intact:EBI-21286600	psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286619|imex:IM-26899-689	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001166.3|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|ensembl:ENSG00000111348.9(gene)|ensembl:ENST00000228945.9(transcript)|ensembl:ENST00000541546.5(transcript)|ensembl:ENST00000541644.5(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005094""(Rho GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071461""(cellular response to redox state)|go:""GO:1901164""(negative regulation of trophoblast cell migration)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|dip:DIP-40959N|panther:PTHR10980(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:DD7261C0213CD30E|rigid:HFTYKzMKVSN2aaGenLsvXzqLfJA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y2L5	uniprotkb:Q83A33	intact:EBI-2820056|uniprotkb:A0JP15|uniprotkb:B3KME5|uniprotkb:Q9H0L2|ensembl:ENSP00000283351.4	intact:EBI-21286457	psi-mi:tppc8_human(display_long)|uniprotkb:TRAPPC8(gene name)|psi-mi:TRAPPC8(display_short)|uniprotkb:KIAA1012(gene name synonym)|uniprotkb:Protein TRS85 homolog(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286538|imex:IM-26899-589	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055754.2|dip:DIP-48280N|ensembl:ENSG00000153339.15(gene)|ensembl:ENST00000283351.10(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0030008""(TRAPP complex)|go:""GO:0032964""(collagen biosynthetic process)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0099022""(vesicle tethering)|go:""GO:1990072""(TRAPPIII protein complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024420|mint:Q9Y2L5|reactome:R-HSA-8876198|panther:PTHR12975(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ofBTdvGAgN6zCUIydAmlZ0BpGsw9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:CEE62E7CBDA33DB3|rigid:v0vfl6yFBiaOd3zRu7ylZPcNsjo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P11021	uniprotkb:Q83A33	intact:EBI-354921|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61|ensembl:ENSP00000324173.6	intact:EBI-21286457	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286484|imex:IM-26899-781	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005338.1|ensembl:ENSG00000044574.9(gene)|ensembl:ENST00000324460.7(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006983""(ER overload response)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021589""(cerebellum structural organization)|go:""GO:0021680""(cerebellar Purkinje cell layer development)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030291""(protein serine/threonine kinase inhibitor activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031204""(post-translational protein targeting to membrane, translocation)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035437""(maintenance of protein localization in endoplasmic reticulum)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042026""(protein refolding)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042470""(melanosome)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060904""(regulation of protein folding in endoplasmic reticulum)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071353""(cellular response to interleukin-4)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1903891""(regulation of ATF6-mediated unfolded protein response)|go:""GO:1903894""(regulation of IRE1-mediated unfolded protein response)|go:""GO:1903895""(negative regulation of IRE1-mediated unfolded protein response)|go:""GO:1903897""(regulation of PERK-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|rcsb pdb:7N1R|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-8874177|reactome:R-HSA-983170|dip:DIP-33189N|panther:PTHR19375(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/25	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:B4B15A1163FE4DA6|rigid:q7xvQYnf6GTdMZLnQWFYhePfbds	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BS91	uniprotkb:Q83A33	intact:EBI-18915901|ensembl:ENSP00000417654.1|uniprotkb:D3DN66|uniprotkb:Q69YY6|uniprotkb:Q6ZMD6|uniprotkb:Q9NWM9|intact:EBI-28986451	intact:EBI-21286457	psi-mi:s35a5_human(display_long)|uniprotkb:Solute carrier family 35 member A5(gene name synonym)|uniprotkb:UNQ164/PRO190(orf name)|uniprotkb:SLC35A5(gene name)|psi-mi:SLC35A5(display_short)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286532|imex:IM-26899-169	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000138459.9(gene)|ensembl:ENST00000492406.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0015165""(pyrimidine nucleotide-sugar transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0055085""(transmembrane transport)|interpro:IPR007271(Nucleotide-sugar transporter)|mint:Q9BS91|refseq:NP_060415.1|refseq:XP_011511250.1|panther:PTHR10231(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:7ncNOFrwj0vIiVZFQNjshXlHU409606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:CADE655C3FFE2DCC|rigid:8UI47S57peLL+NyyR358dUYsnZI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P35555	uniprotkb:Q83A11	intact:EBI-2505934|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6|ensembl:ENSP00000325527.5	intact:EBI-21286600	psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286637|imex:IM-26899-53	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1885""|efo:""Orphanet:2084""|efo:""Orphanet:2462""|efo:""Orphanet:2623""|efo:""Orphanet:2833""|efo:""Orphanet:284963""|efo:""Orphanet:284979""|efo:""Orphanet:300382""|efo:""Orphanet:3449""|efo:""Orphanet:91387""|efo:""Orphanet:969""|dip:DIP-29985N|ensembl:ENSG00000166147.16(gene)|ensembl:ENST00000316623.10(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001527""(microfibril)|go:""GO:0001656""(metanephros development)|go:""GO:0005178""(integrin binding)|go:""GO:0005179""(hormone activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010467""(gene expression)|go:""GO:0030023""(extracellular matrix constituent conferring elasticity)|go:""GO:0031012""(extracellular matrix)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035582""(sequestering of BMP in extracellular matrix)|go:""GO:0035583""(sequestering of TGFbeta in extracellular matrix)|go:""GO:0042802""(identical protein binding)|go:""GO:0043010""(camera-type eye development)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0048286""(lung alveolus development)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:1990314""(cellular response to insulin-like growth factor stimulus)|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|interpro:IPR049388|interpro:IPR049883|interpro:IPR052080|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|panther:PTHR24039(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/28	rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:EE33101E6B2EC526|rigid:+gemyHZCOFt6uevb+oG7XGms4jw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P31491	uniprotkb:Q04206	intact:EBI-2840013	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	psi-mi:yera_yerpe(display_long)|uniprotkb:yerA(gene name)|psi-mi:yerA(display_short)|uniprotkb:YPCD1.05c(locus name)|uniprotkb:y5069(locus name)|uniprotkb:y0078(locus name)|uniprotkb:YP_pCD82(locus name)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592190|imex:IM-26497-101	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395142.1|refseq:NP_857763.1|refseq:NP_857968.1|interpro:IPR005416(Type III secretion chaperone SycE, Gram-negative bacterial)|interpro:IPR010261(Tir chaperone)|go:""GO:0030254""(protein secretion by the type III secretion system)|rcsb pdb:1JYA|rcsb pdb:1K6Z|refseq:WP_002213403.1|mint:P31491"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2025/03/26	rogid:qrGc2l9rhnr0MEOXqSUh/YZ9d6E632	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:B5402F950F14A5F7|rigid:/CGYaWoWj3nE2V3fYEgKcdTEDcw	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P69976	uniprotkb:Q04206	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592198|imex:IM-26497-1	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2025/03/26	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:7A5B0EAC34C2C1A7|rigid:jeWbOKx11xz2QQbLllkaURGyn0E	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A2U2H0Y9	uniprotkb:Q04206	intact:EBI-20592206|uniprotkb:A0A380PFV1|uniprotkb:Q0WAD5|uniprotkb:Q74RA0|uniprotkb:Q7CKZ6|uniprotkb:A0A384L2L7	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	psi-mi:a0a2u2h0y9_yerpe(display_long)|uniprotkb:YPO3877(locus name)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592217|imex:IM-26497-241	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050263|go:""GO:0007155""(cell adhesion)|go:""GO:0009289""(pilus)|interpro:IPR039458|refseq:WP_002211997.1|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|refseq:YP_002348753.1|mint:A0A2U2H0Y9"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2025/03/26	rogid:Z2vEIx26i3KjVJslLNlEQhiBB84632	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:80684C9F624CE122|rigid:nv6JLmf4ht7Hldm/Xjo3DlQlXSA	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A384KL23	uniprotkb:Q04206	intact:EBI-20592225|uniprotkb:A0A3G5LCU0|uniprotkb:A0A2S9PAT5|uniprotkb:Q0WCX0|uniprotkb:A0A5P8YLR8	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	psi-mi:a0a384kl23_yerpe(display_long)|uniprotkb:YPO2940(locus name)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592236|imex:IM-26497-103	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050263|go:""GO:0009289""(pilus)|go:""GO:0043709""(cell adhesion involved in single-species biofilm formation)|interpro:IPR000259(Fimbrial protein)|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|panther:PTHR33420(orthology-group)|refseq:YP_002347868.1|mint:A0A384KL23"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	-	-	-	figure legend:st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2025/03/26	rogid:MuYUsndYAjFtJ9rQDWl+Jk24p2c632	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:FB30FFD242261C1E|rigid:bWLcm69osQYP7c7Psjj5YMq6Y2Y	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P61417	uniprotkb:O15162	intact:EBI-20592244|uniprotkb:P21209	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592260|imex:IM-26497-41	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	intact-crc:15E67BB32FA462BF|rigid:XDB8J41aYSXNZc/UsNz/HatDMls	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q56973	uniprotkb:O15162	intact:EBI-20592268	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	psi-mi:yscb_yerpe(display_long)|uniprotkb:yscB(gene name)|psi-mi:yscB(display_short)|uniprotkb:Yop proteins translocation protein B(gene name synonym)|uniprotkb:YPCD1.51(locus name)|uniprotkb:YP_pCD32(locus name)|uniprotkb:y0030(locus name)|uniprotkb:y5027(locus name)	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592286|imex:IM-26497-301	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|rcsb pdb:1XKP|refseq:NP_395185.1|refseq:NP_857731.1|refseq:NP_857926.1|refseq:WP_002212925.1|interpro:IPR013353(Type III secretion system chaperone YscB)|interpro:IPR010261(Tir chaperone)|mint:Q56973"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:Vy7YorWh6UR5bH680AS7SaUyWKs632	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	intact-crc:A5CB4B421214947F|rigid:7nuMpnqtjPvoF0h14V8pJYK+kII	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P69974	uniprotkb:O15162	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592294|imex:IM-26497-181	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	intact-crc:50ED3415877AEF04|rigid:kvov8BIuJVuyYWG//UR65ugqhHU	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q8ZG77	uniprotkb:O15162	intact:EBI-20592302|uniprotkb:Q0WGY2|uniprotkb:Q74VI2|uniprotkb:Q8D056	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	psi-mi:ompa_yerpe(display_long)|uniprotkb:Outer membrane porin A(gene name synonym)|uniprotkb:y2735(locus name)|uniprotkb:ompA(gene name)|psi-mi:ompA(display_short)|uniprotkb:ompA1(gene name synonym)|uniprotkb:YPO1435(locus name)|uniprotkb:YP_1326(locus name)	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592328|imex:IM-26497-183	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050330|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|refseq:WP_002213066.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR002368(Outer membrane protein, OmpA)|panther:PTHR30128(orthology-group)|refseq:YP_002346456.1|mint:Q8ZG77"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	-	-	-	figure legend:st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:q86tZqya2906j6c/oL0NQ6Kmy84632	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	intact-crc:7E80E468D806106C|rigid:unDGp+G0mCIYeYLbKVa9YA2UTWU	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q56973	uniprotkb:Q9NSC5	intact:EBI-20592268	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|ensembl:ENSP00000376162.2|ensembl:ENSP00000439937.1|ensembl:ENSP00000446026.1|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|intact:EBI-10175777|uniprotkb:B2RA10	psi-mi:yscb_yerpe(display_long)|uniprotkb:yscB(gene name)|psi-mi:yscB(display_short)|uniprotkb:Yop proteins translocation protein B(gene name synonym)|uniprotkb:YPCD1.51(locus name)|uniprotkb:YP_pCD32(locus name)|uniprotkb:y0030(locus name)|uniprotkb:y5027(locus name)	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592336|imex:IM-26497-781	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|rcsb pdb:1XKP|refseq:NP_395185.1|refseq:NP_857731.1|refseq:NP_857926.1|refseq:WP_002212925.1|interpro:IPR013353(Type III secretion system chaperone YscB)|interpro:IPR010261(Tir chaperone)|mint:Q56973"	"refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128.19(gene)|ensembl:ENST00000392351.8(transcript)|ensembl:ENST00000539827.5(transcript)|ensembl:ENST00000542541.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0007216""(G protein-coupled glutamate receptor signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030425""(dendrite)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0035256""(G protein-coupled glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045178""(basal part of cell)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2001256""(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|interpro:IPR045027|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|panther:PTHR10918(orthology-group)"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:Vy7YorWh6UR5bH680AS7SaUyWKs632	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	intact-crc:6B95F54298F1FA36|rigid:EHFlq3xccako5YRCfrWJ7Dy3fz0	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A3N4B5W9	uniprotkb:Q9NSC5	intact:EBI-20592344|uniprotkb:A0A0H2W7W4|uniprotkb:Q74QP5|uniprotkb:Q7CGM7|uniprotkb:A0A384KXH8	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|ensembl:ENSP00000376162.2|ensembl:ENSP00000439937.1|ensembl:ENSP00000446026.1|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|intact:EBI-10175777|uniprotkb:B2RA10	psi-mi:a0a3n4b5w9_yerpe(display_long)|uniprotkb:YPO1006(locus name)	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592354|imex:IM-26497-243	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|go:""GO:0005576""(extracellular region)|refseq:WP_002214025.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR001611(Leucine-rich repeat)|panther:PTHR47114(orthology-group)|refseq:YP_002346051.1|mint:A0A3N4B5W9"	"refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128.19(gene)|ensembl:ENST00000392351.8(transcript)|ensembl:ENST00000539827.5(transcript)|ensembl:ENST00000542541.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0007216""(G protein-coupled glutamate receptor signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030425""(dendrite)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0035256""(G protein-coupled glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045178""(basal part of cell)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2001256""(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|interpro:IPR045027|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|panther:PTHR10918(orthology-group)"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:J2v9cU/a7BimPcEvtvodoAcWK2g632	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	intact-crc:4ADFAD70738C6297|rigid:LSThQfpaW/DDN9FrSFwvXmoCNbE	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A1U8QN96	uniprotkb:Q86X55	intact:EBI-20592362|uniprotkb:O68745|uniprotkb:Q74YN8|uniprotkb:Q7ARE5	intact:EBI-2339854|uniprotkb:A6NN38|ensembl:ENSP00000325690.4	psi-mi:a0a1u8qn96_yerpe(display_long)|uniprotkb:YPMT1.27c(locus name)	psi-mi:carm1_human(display_long)|uniprotkb:CARM1(gene name)|psi-mi:CARM1(display_short)|uniprotkb:PRMT4(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 4(gene name synonym)|uniprotkb:Coactivator-associated arginine methyltransferase 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592379|imex:IM-26497-43	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055085""(transmembrane transport)|interpro:IPR015854(ABC transporter, lipoprotein release, LolD)|refseq:NP_395365.2|refseq:YP_093906.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR027417|interpro:IPR025662|mint:A0A1U8QN96"	"refseq:NP_954592.1|refseq:XP_005259765.1|dip:DIP-44071N|ensembl:ENSG00000142453.13(gene)|ensembl:ENST00000327064.9(transcript)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008276""(protein methyltransferase activity)|interpro:IPR011993(Pleckstrin homology-type)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008469""(histone arginine N-methyltransferase activity)|go:""GO:0016274""(protein-arginine N-methyltransferase activity)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032259""(methylation)|go:""GO:0033146""(regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0035242""(protein-arginine omega-N asymmetric methyltransferase activity)|go:""GO:0035642""(histone H3R17 methyltransferase activity)|go:""GO:0042054""(histone methyltransferase activity)|go:""GO:0043596""(nuclear replication fork)|go:""GO:0044020""(histone H4R3 methyltransferase activity)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0045943""(positive regulation of transcription by RNA polymerase I)|go:""GO:0051591""(response to cAMP)|go:""GO:0062122""(histone H3K37 methyltransferase activity)|go:""GO:0070577""(lysine-acetylated histone binding)|go:""GO:0070611""(histone H3R2 methyltransferase activity)|go:""GO:0071932""(replication fork reversal)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140592""(histone H3R8 methyltransferase activity)|go:""GO:0140759""(histone H3K56 methyltransferase activity)|go:""GO:0140903""(histone H3R26 methyltransferase activity)|go:""GO:0140984""(histone H4K12 methyltransferase activity)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|go:""GO:1990259""(histone H2A Q104 methyltransferase activity)|go:""GO:2000171""(negative regulation of dendrite development)|interpro:IPR020989|interpro:IPR025799|interpro:IPR029063|interpro:IPR055135|mint:Q86X55|rcsb pdb:2Y1W|rcsb pdb:2Y1X|rcsb pdb:4IKP|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5DXJ|rcsb pdb:5U4X|rcsb pdb:6ARJ|rcsb pdb:6ARV|rcsb pdb:6D2L|rcsb pdb:6DVR|rcsb pdb:6IZQ|rcsb pdb:6S70|rcsb pdb:6S71|rcsb pdb:6S74|rcsb pdb:6S77|rcsb pdb:6S79|rcsb pdb:6S7A|rcsb pdb:6S7B|rcsb pdb:6S7C|rcsb pdb:7FAI|rcsb pdb:7FAJ|rcsb pdb:7U9I|rcsb pdb:8G2H|rcsb pdb:8G2I|rcsb pdb:8SIG|rcsb pdb:8SIH|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-6804114|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|panther:PTHR11006(orthology-group)"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2025/01/07	rogid:FqRfJOD7v8FxU5HP/gF/YtZLhBY632	rogid:1x1bUjqcA/ZpmrSsSM545ReYH2A9606	intact-crc:BCC0F8C0954859C8|rigid:svwfJlJ1QsNVCSZhRvNSCdaIQtw	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q56975	uniprotkb:O43681	intact:EBI-6413916|uniprotkb:Q74YX9|uniprotkb:Q7BTX7|uniprotkb:A0A384KEC2|uniprotkb:A0A0H2W058|uniprotkb:A0A380SBC7|uniprotkb:A0A3G5L0Z0|uniprotkb:A0A9Y2Y7E4|uniprotkb:A0A2U2GUL2	intact:EBI-2515857|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109|ensembl:ENSP00000349887.3|ensembl:ENSP00000466379.1	psi-mi:q56975_yerpe(display_long)|uniprotkb:yscD(gene name)|psi-mi:yscD(display_short)|uniprotkb:YPCD1.53(locus name)|uniprotkb:Y0028(gene name synonym)	psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592387|imex:IM-26497-3	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|rcsb pdb:4A0E|interpro:IPR053946|interpro:IPR053947|mint:Q56975|refseq:WP_002212919.1|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012843(Type III secretion system YscD/HrpQ)|refseq:NP_395187.1|refseq:NP_857729.1|refseq:NP_857924.1|interpro:IPR032030|interpro:IPR032034"	"ensembl:ENSG00000198356.12(gene)|ensembl:ENST00000357332.8(transcript)|ensembl:ENST00000591090.5(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0015105""(arsenite transmembrane transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032977""(membrane insertase activity)|go:""GO:0043529""(GET complex)|go:""GO:0045048""(protein insertion into ER membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|rcsb pdb:8CQZ|rcsb pdb:8CR1|rcsb pdb:8CR2|reactome:R-HSA-9609523|refseq:NP_004308.2|efo:""Orphanet:154""|panther:PTHR10803(orthology-group)"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:/RZ00PckilfW1XiwoyHOfRpTuiI632	rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606	intact-crc:DE74712DA23592FC|rigid:MK4arSJGVAdc5HccDmCQMs5LPdE	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P69974	uniprotkb:Q13077	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994.3|ensembl:ENSP00000443183.1	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592395|imex:IM-26497-141	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	"refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558.11(gene)|ensembl:ENST00000373887.8(transcript)|ensembl:ENST00000540010.1(transcript)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:2001236""(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR032070|interpro:IPR037306|interpro:IPR049342|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|panther:PTHR10131(orthology-group)"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606	intact-crc:FB68715DDE5D085B|rigid:63rWJJIm3ad1eOOI1zu6qqGK2Cs	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9RI12	uniprotkb:P50552	intact:EBI-2849107|uniprotkb:O68717	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|ensembl:ENSP00000245932.5|intact:EBI-28992147	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592403|imex:IM-26497-5	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	"refseq:NP_003361.1|ensembl:ENSG00000125753.15(gene)|ensembl:ENST00000245932.11(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007411""(axon guidance)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031527""(filopodium membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|mint:P50552|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR038023|rcsb pdb:1EGX|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:8GAT|rcsb pdb:8GAU|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N|panther:PTHR11202(orthology-group)"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2025/02/28	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	intact-crc:8673C758AFDFE96C|rigid:4Z5QmUj15MM5D/iOO3yGcpUQ41o	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:O68704	uniprotkb:O00339	intact:EBI-20592411|uniprotkb:A0A3G5L121|uniprotkb:A0A384LBT1|uniprotkb:Q7ARJ5|uniprotkb:A0A2S9PEG7|uniprotkb:A0A5P8YM58	intact:EBI-949020|uniprotkb:A8K106|uniprotkb:E7EW74|uniprotkb:E9PD48|uniprotkb:E9PGL2|uniprotkb:Q6UWA5|uniprotkb:Q7Z5X1|uniprotkb:Q8NDE6|uniprotkb:Q96FT5|uniprotkb:Q9NSZ1|ensembl:ENSP00000254898.6|ensembl:ENSP00000430487.1	psi-mi:o68704_yerpe(display_long)|uniprotkb:yopK(gene name)|psi-mi:yopK(display_short)|uniprotkb:yopQ(gene name synonym)|uniprotkb:Y0066(gene name synonym)|uniprotkb:YPCD1.19c(locus name)	psi-mi:matn2_human(display_long)|uniprotkb:MATN2(gene name)|psi-mi:MATN2(display_short)|uniprotkb:UNQ193/PRO219(orf name)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592423|imex:IM-26497-185	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|refseq:NP_395154.1|refseq:NP_857759.1|refseq:NP_857959.1|refseq:WP_002213007.1|interpro:IPR016505(Type III secreted protein YopQ)|mint:O68704"	"dip:DIP-47267N|refseq:NP_002371.3|refseq:NP_085072.2|refseq:NP_001304677.1|ensembl:ENSG00000132561.14(gene)|ensembl:ENST00000254898.7(transcript)|ensembl:ENST00000520016.5(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008347""(glial cell migration)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031104""(dendrite regeneration)|go:""GO:0048678""(response to axon injury)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0120216""(matrilin complex)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR019466|interpro:IPR026823|interpro:IPR036337|interpro:IPR036465|interpro:IPR049883|interpro:IPR050525|mint:O00339|panther:PTHR24020(orthology-group)"	-	-	-	figure legend:st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:v8uTxKoDAiSSSQ1kseuCf0e8QgE632	rogid:umvJixncdhOkQvywPNFjPo1Aqx89606	intact-crc:FFD0C8A6CFD5CBD6|rigid:kqfIEzO/7SNMVbtYQPqjPMuHIm0	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P68590	uniprotkb:Q15276	intact:EBI-2845098|uniprotkb:Q00929	intact:EBI-447043|uniprotkb:O95369|uniprotkb:Q8IVX3|uniprotkb:B2RAG7|ensembl:ENSP00000445408.2	psi-mi:yopr_yerpe(display_long)|uniprotkb:yscH(gene name)|psi-mi:yscH(display_short)|uniprotkb:lcrP(gene name synonym)|uniprotkb:Yersinia outer protein R(gene name synonym)|uniprotkb:Yersinia secretion protein H(gene name synonym)|uniprotkb:yopR(gene name synonym)|uniprotkb:YPCD1.57(locus name)|uniprotkb:YP_pCD26(locus name)|uniprotkb:y0024(locus name)|uniprotkb:y5021(locus name)	psi-mi:rabe1_human(display_long)|uniprotkb:Rabaptin-5(gene name synonym)|uniprotkb:Rabaptin-5alpha(gene name synonym)|uniprotkb:Rabaptin-4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-17(gene name synonym)|uniprotkb:RABEP1(gene name)|psi-mi:RABEP1(display_short)|uniprotkb:RABPT5(gene name synonym)|uniprotkb:RABPT5A(gene name synonym)|uniprotkb:RAB5EP(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592431|imex:IM-26497-143	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013349(Type III secretion system effector YopR)|refseq:NP_395191.1|refseq:NP_857725.1|refseq:NP_857920.1|go:""GO:0005576""(extracellular region)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|rcsb pdb:1Z21|refseq:WP_002212915.1|mint:P68590|interpro:IPR041814"	"refseq:NP_001278510.1|refseq:NP_001077054.1|refseq:NP_004694.2|dip:DIP-29350N|rcsb pdb:1TU3|ensembl:ENSG00000029725.17(gene)|ensembl:ENST00000537505.6(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006915""(apoptotic process)|go:""GO:0008083""(growth factor activity)|go:""GO:0015031""(protein transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055037""(recycling endosome)|go:""GO:0061025""(membrane fusion)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1903441""(protein localization to ciliary membrane)|interpro:IPR003914(Rabaptin)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR018514|mint:Q15276|rcsb pdb:1P4U|rcsb pdb:1X79|rcsb pdb:4N3Y|rcsb pdb:4N3Z|rcsb pdb:4Q9U|reactome:R-HSA-8854214|panther:PTHR31179(orthology-group)"	-	-	-	figure legend:st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2025/02/26	rogid:vLBOGgil8yDmtkZgVzl8ti6IGok632	rogid:FDHgN8w6jbAPC3iQfeLY6sdLkrs9606	intact-crc:066D0C9368E4EBF2|rigid:dFaB6KWbrbzY26N027aBuGiaGQI	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:O68743	uniprotkb:O43294	intact:EBI-2849869|uniprotkb:A0A384L9N9|uniprotkb:Q74YP1|uniprotkb:Q7ARA6|uniprotkb:Q7BT23|uniprotkb:Q65AP4|uniprotkb:A0A1U8QGX5|uniprotkb:A0A5P8YM11|uniprotkb:A0A2U2H133	intact:EBI-1051449|uniprotkb:Q9BPW3|uniprotkb:Q9Y2V5|uniprotkb:B2R8D5|ensembl:ENSP00000378332.3	psi-mi:o68743_yerpe(display_long)|uniprotkb:YPMT1.25Ac(gene name)|psi-mi:YPMT1.25Ac(display_short)	psi-mi:tgfi1_human(display_long)|uniprotkb:TGFB1I1(gene name)|psi-mi:TGFB1I1(display_short)|uniprotkb:ARA55(gene name synonym)|uniprotkb:Hydrogen peroxide-inducible clone 5 protein(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 55 kDa(gene name synonym)|uniprotkb:Androgen receptor coactivator 55 kDa protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592439|imex:IM-26497-105	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_857662.1|refseq:NP_395362.1|refseq:YP_093903.1|refseq:WP_000176291.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:O68743"	"refseq:NP_001035919.1|refseq:NP_001158191.1|refseq:NP_057011.2|dip:DIP-5931N|ensembl:ENSG00000140682.19(gene)|ensembl:ENST00000394863.8(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0016363""(nuclear matrix)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045165""(cell fate commitment)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048495""(Roundabout binding)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0070411""(I-SMAD binding)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|interpro:IPR047075|mint:O43294|panther:PTHR24216(orthology-group)"	-	-	-	figure legend:st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:/jUgpNFZ2rE3SwY62pqgY9qM8xs632	rogid:ekkGbwdFenBhBn0HzJjd4Szi61U9606	intact-crc:6B48CD79C704AD95|rigid:KAHFaw4jaWGDlNHoMkJw56+D/eA	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A380PHX5	uniprotkb:Q9BRF8	intact:EBI-20592447|uniprotkb:A0A0H2W9V8|uniprotkb:Q74PA8|uniprotkb:Q7CFN2|uniprotkb:A0A384KIL4	intact:EBI-11305102|uniprotkb:Q9H9M9|uniprotkb:Q6MZY9|uniprotkb:Q9NUT6|uniprotkb:B4DQ68|ensembl:ENSP00000371193.4	psi-mi:a0a380phx5_yerpe(display_long)|uniprotkb:YPO4110(locus name)	psi-mi:cpped_human(display_long)|uniprotkb:CPPED1(gene name)|psi-mi:CPPED1(display_short)|uniprotkb:CSTP1(gene name synonym)|uniprotkb:Calcineurin-like phosphoesterase domain-containing protein 1(gene name synonym)|uniprotkb:Complete S-transactivated protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20976146|imex:IM-26497-783	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|refseq:WP_002215571.1|interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|interpro:IPR035906|interpro:IPR043429|panther:PTHR30614(orthology-group)|refseq:YP_002348961.1|mint:A0A380PHX5"	"refseq:NP_001092925.1|refseq:NP_060810.2|ensembl:ENSG00000103381.12(gene)|ensembl:ENST00000381774.9(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0046872""(metal ion binding)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR041867|interpro:IPR051918|mint:Q9BRF8|reactome:R-HSA-6798695|panther:PTHR43143(orthology-group)"	-	-	-	figure legend:f1d st5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/04	2024/11/14	rogid:YPcZDpMnrJjsb3Dz7RiNnm7cFl4632	rogid:5bdWSCd8D97nsTvUbxWdeStJJb89606	intact-crc:9544663E8D8E3F57|rigid:y+PiCB2ekUZerqMjz6VdxJNv1Zo	false	glutathione s tranferase tag:n-n	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9RI12	uniprotkb:P50552	intact:EBI-2849107|uniprotkb:O68717	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|ensembl:ENSP00000245932.5|intact:EBI-28992147	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592475|imex:IM-26497-247	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	"refseq:NP_003361.1|ensembl:ENSG00000125753.15(gene)|ensembl:ENST00000245932.11(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007411""(axon guidance)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031527""(filopodium membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|mint:P50552|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR038023|rcsb pdb:1EGX|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:8GAT|rcsb pdb:8GAU|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N|panther:PTHR11202(orthology-group)"	-	-	-	figure legend:f5a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2018/05/04	2025/02/28	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	intact-crc:4A2C89A9F559EFE5|rigid:4Z5QmUj15MM5D/iOO3yGcpUQ41o	false	myc tag:?-?	green fluorescent protein tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9RI12	uniprotkb:P50552	intact:EBI-2849107|uniprotkb:O68717	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|ensembl:ENSP00000245932.5|intact:EBI-28992147	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20592483|imex:IM-26497-381	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	"refseq:NP_003361.1|ensembl:ENSG00000125753.15(gene)|ensembl:ENST00000245932.11(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007411""(axon guidance)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031527""(filopodium membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|mint:P50552|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR038023|rcsb pdb:1EGX|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:8GAT|rcsb pdb:8GAU|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N|panther:PTHR11202(orthology-group)"	-	-	-	figure legend:f5a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2018/05/04	2025/02/28	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	intact-crc:4B05DA8594CF4FE5|rigid:4Z5QmUj15MM5D/iOO3yGcpUQ41o	false	myc tag:?-?	green fluorescent protein tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P01889	uniprotkb:P31491	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	intact:EBI-2840013	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:yera_yerpe(display_long)|uniprotkb:yerA(gene name)|psi-mi:yerA(display_short)|uniprotkb:YPCD1.05c(locus name)|uniprotkb:y5069(locus name)|uniprotkb:y0078(locus name)|uniprotkb:YP_pCD82(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20816934|imex:IM-26497-382	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"refseq:NP_395142.1|refseq:NP_857763.1|refseq:NP_857968.1|interpro:IPR005416(Type III secretion chaperone SycE, Gram-negative bacterial)|interpro:IPR010261(Tir chaperone)|go:""GO:0030254""(protein secretion by the type III secretion system)|rcsb pdb:1JYA|rcsb pdb:1K6Z|refseq:WP_002213403.1|mint:P31491"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	rogid:qrGc2l9rhnr0MEOXqSUh/YZ9d6E632	intact-crc:11D349E0945D6707|rigid:FsqeY3Nqa1fXq5NTSZ3wG8PHQAk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q04206	uniprotkb:P31491	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	intact:EBI-2840013	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:yera_yerpe(display_long)|uniprotkb:yerA(gene name)|psi-mi:yerA(display_short)|uniprotkb:YPCD1.05c(locus name)|uniprotkb:y5069(locus name)|uniprotkb:y0078(locus name)|uniprotkb:YP_pCD82(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20816940|imex:IM-26497-482	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	"refseq:NP_395142.1|refseq:NP_857763.1|refseq:NP_857968.1|interpro:IPR005416(Type III secretion chaperone SycE, Gram-negative bacterial)|interpro:IPR010261(Tir chaperone)|go:""GO:0030254""(protein secretion by the type III secretion system)|rcsb pdb:1JYA|rcsb pdb:1K6Z|refseq:WP_002213403.1|mint:P31491"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rogid:qrGc2l9rhnr0MEOXqSUh/YZ9d6E632	intact-crc:2EEF1C48E1A419CF|rigid:/CGYaWoWj3nE2V3fYEgKcdTEDcw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q04206	uniprotkb:P31493	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	intact:EBI-20816946	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:yope_yerpe(display_long)|uniprotkb:yopE(gene name)|psi-mi:yopE(display_short)|uniprotkb:yop25(gene name synonym)|uniprotkb:YPCD1.06(locus name)|uniprotkb:y5068(locus name)|uniprotkb:y0077(locus name)|uniprotkb:YP_pCD81(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20816968|imex:IM-26497-522	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	"mint:P31493|refseq:NP_395143.1|refseq:NP_857762.1|refseq:NP_857967.1|refseq:WP_002229754.1|interpro:IPR003537(Yersinia virulence determinant YopE)|interpro:IPR014773(Yersinia virulence determinant YopE, C-terminal)|interpro:IPR037168|interpro:IPR015110(YopE, N terminal)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0050765""(negative regulation of phagocytosis)|rcsb pdb:1HY5"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rogid:I6+hhcn5d6JJwwIs/uBMeVTlRsQ632	intact-crc:52595640C1B0704F|rigid:Yn65Frigp6bKUcmkyCqpL/gV+Rk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BTA9	uniprotkb:Q7ARJ6	intact:EBI-749118|intact:EBI-947208|uniprotkb:C9JBT9|uniprotkb:Q5JU75|uniprotkb:Q5JU77|uniprotkb:Q53EN9|uniprotkb:Q5VXK0|uniprotkb:Q5VXK2|uniprotkb:Q8TCK1|uniprotkb:Q96DP3|uniprotkb:Q96FW6|uniprotkb:Q96JI3|uniprotkb:A8K2A9|intact:EBI-1105304|uniprotkb:D3DRW5|uniprotkb:D3DRW6|uniprotkb:D3DRW7|ensembl:ENSP00000346986.4	intact:EBI-20817003|uniprotkb:Q74YW6|uniprotkb:Q9ZGW5	psi-mi:wac_human(display_long)|uniprotkb:WAC(gene name)|psi-mi:WAC(display_short)|uniprotkb:KIAA1844(gene name synonym)	psi-mi:q7arj6_yerpe(display_long)|uniprotkb:Y0068(gene name)|psi-mi:Y0068(display_short)|uniprotkb:YPCD1.16c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817018|imex:IM-26497-622	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000095787.26(gene)|ensembl:ENST00000354911.9(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006974""(DNA damage response)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016607""(nuclear speck)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:1904263""(positive regulation of TORC1 signaling)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|interpro:IPR038867|mint:Q9BTA9|reactome:R-HSA-8866654|refseq:NP_057712.2|refseq:NP_567822.1|refseq:NP_567823.1|refseq:XP_011517793.1|efo:""Orphanet:284169""|efo:""Orphanet:466950""|panther:PTHR15911(orthology-group)"	"mint:Q7ARJ6|interpro:IPR051839|refseq:NP_395152.1|refseq:NP_857960.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR002514(Transposase IS3/IS911)|panther:PTHR33215(orthology-group)|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:TuCxRb98Y5EGRbK1RRNMi/VnXV89606	rogid:gt/5xlzvpxY6kMqRM2g1FkNFUuY632	intact-crc:D3C4A1AB6F95B1D8|rigid:GRyv0iZLrkog066097ZEqjmZmPM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15025	uniprotkb:P31493	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|ensembl:ENSP00000317891.7|ensembl:ENSP00000428187.1|ensembl:ENSP00000428404.2|ensembl:ENSP00000430279.2|ensembl:ENSP00000430760.1|uniprotkb:B7Z699|uniprotkb:Q6N077|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-20816946	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:yope_yerpe(display_long)|uniprotkb:yopE(gene name)|psi-mi:yopE(display_short)|uniprotkb:yop25(gene name synonym)|uniprotkb:YPCD1.06(locus name)|uniprotkb:y5068(locus name)|uniprotkb:y0077(locus name)|uniprotkb:YP_pCD81(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20816974|imex:IM-26497-722	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000145901.17(gene)|ensembl:ENST00000315050.11(transcript)|ensembl:ENST00000520695.6(transcript)|ensembl:ENST00000521001.2(transcript)|ensembl:ENST00000521591.6(transcript)|ensembl:ENST00000522226.5(transcript)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006412""(translation)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0009101""(glycoprotein biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:1903003""(positive regulation of protein deubiquitination)|mint:Q15025|rcsb pdb:7EAL|rcsb pdb:7EAO|rcsb pdb:7EB9|rcsb pdb:8YFK|rcsb pdb:8YFM|rcsb pdb:8YFN|reactome:R-HSA-5689896|refseq:NP_001239314.1|refseq:NP_001239315.1|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:NP_006049.3|refseq:XP_006714814.1|refseq:XP_006714815.1|dip:DIP-27577N|efo:""Orphanet:536""|panther:PTHR31882(orthology-group)"	"mint:P31493|refseq:NP_395143.1|refseq:NP_857762.1|refseq:NP_857967.1|refseq:WP_002229754.1|interpro:IPR003537(Yersinia virulence determinant YopE)|interpro:IPR014773(Yersinia virulence determinant YopE, C-terminal)|interpro:IPR037168|interpro:IPR015110(YopE, N terminal)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0050765""(negative regulation of phagocytosis)|rcsb pdb:1HY5"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:I6+hhcn5d6JJwwIs/uBMeVTlRsQ632	intact-crc:BB20E300CAD4B253|rigid:aJb107kzJwRiuFZjrVPaKahehP0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43815	uniprotkb:Q7ARJ6	intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918.4|uniprotkb:Q53TQ8|uniprotkb:Q9NP38	intact:EBI-20817003|uniprotkb:Q74YW6|uniprotkb:Q9ZGW5	psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short)	psi-mi:q7arj6_yerpe(display_long)|uniprotkb:Y0068(gene name)|psi-mi:Y0068(display_short)|uniprotkb:YPCD1.16c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817024|imex:IM-26497-384	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003153.2|ensembl:ENSG00000115808.13(gene)|ensembl:ENST00000263918.9(transcript)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016358""(dendrite development)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030425""(dendrite)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR051488|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|reactome:R-HSA-9700645|reactome:R-HSA-9725370|panther:PTHR15653(orthology-group)"	"mint:Q7ARJ6|interpro:IPR051839|refseq:NP_395152.1|refseq:NP_857960.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR002514(Transposase IS3/IS911)|panther:PTHR33215(orthology-group)|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606	rogid:gt/5xlzvpxY6kMqRM2g1FkNFUuY632	intact-crc:F47D979BC65F5C29|rigid:0F0pbAcwAXwcmupUvTNGjkQP5go	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9HBI0	uniprotkb:Q7ARJ8	intact:EBI-3921217|uniprotkb:Q9NSG1|uniprotkb:Q9BQX5|uniprotkb:B4DDW5|uniprotkb:E7EVM6|ensembl:ENSP00000391453.1|ensembl:ENSP00000391583.2	intact:EBI-20816980|uniprotkb:A0A2U2GUY9|uniprotkb:A0A0H2W1K2|uniprotkb:Q74YW1|uniprotkb:Q9ZGW2|uniprotkb:A0A384KFE6|uniprotkb:A0A5P8YM89	psi-mi:parvg_human(display_long)|uniprotkb:PARVG(gene name)|psi-mi:PARVG(display_short)	psi-mi:q7arj8_yerpe(display_long)|uniprotkb:Y0075(gene name)|psi-mi:Y0075(display_short)|uniprotkb:YPCD1.08c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20816997|imex:IM-26497-682	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001131077.1|refseq:NP_071424.1|refseq:XP_005261759.1|ensembl:ENSG00000138964.18(gene)|ensembl:ENST00000422871.5(transcript)|ensembl:ENST00000444313.8(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0071963""(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI0|panther:PTHR12114(orthology-group)"	mint:Q7ARJ8|interpro:IPR051803|refseq:NP_395145.1|refseq:NP_857965.1|refseq:WP_002213360.1|interpro:IPR028344|interpro:IPR007712(Plasmid stabilization system)|interpro:IPR035093|panther:PTHR33755(orthology-group)	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:s8zEh4PNxhegxr87YnUxAmrb3BE9606	rogid:Lo9W+mBHiIzqaTNdrA7oTjS/384632	intact-crc:83113AA38D856CF1|rigid:eD7P1hxflR+fcTVGiSuZfIDRlIU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O00339	uniprotkb:O68704	intact:EBI-949020|uniprotkb:A8K106|uniprotkb:E7EW74|uniprotkb:E9PD48|uniprotkb:E9PGL2|uniprotkb:Q6UWA5|uniprotkb:Q7Z5X1|uniprotkb:Q8NDE6|uniprotkb:Q96FT5|uniprotkb:Q9NSZ1|ensembl:ENSP00000254898.6|ensembl:ENSP00000430487.1	intact:EBI-20592411|uniprotkb:A0A3G5L121|uniprotkb:A0A384LBT1|uniprotkb:Q7ARJ5|uniprotkb:A0A2S9PEG7|uniprotkb:A0A5P8YM58	psi-mi:matn2_human(display_long)|uniprotkb:MATN2(gene name)|psi-mi:MATN2(display_short)|uniprotkb:UNQ193/PRO219(orf name)	psi-mi:o68704_yerpe(display_long)|uniprotkb:yopK(gene name)|psi-mi:yopK(display_short)|uniprotkb:yopQ(gene name synonym)|uniprotkb:Y0066(gene name synonym)|uniprotkb:YPCD1.19c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817036|imex:IM-26497-724	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-47267N|refseq:NP_002371.3|refseq:NP_085072.2|refseq:NP_001304677.1|ensembl:ENSG00000132561.14(gene)|ensembl:ENST00000254898.7(transcript)|ensembl:ENST00000520016.5(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008347""(glial cell migration)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031104""(dendrite regeneration)|go:""GO:0048678""(response to axon injury)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0120216""(matrilin complex)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR019466|interpro:IPR026823|interpro:IPR036337|interpro:IPR036465|interpro:IPR049883|interpro:IPR050525|mint:O00339|panther:PTHR24020(orthology-group)"	"go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|refseq:NP_395154.1|refseq:NP_857759.1|refseq:NP_857959.1|refseq:WP_002213007.1|interpro:IPR016505(Type III secreted protein YopQ)|mint:O68704"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:umvJixncdhOkQvywPNFjPo1Aqx89606	rogid:v8uTxKoDAiSSSQ1kseuCf0e8QgE632	intact-crc:22708B159C675FD4|rigid:kqfIEzO/7SNMVbtYQPqjPMuHIm0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:O68704	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20592411|uniprotkb:A0A3G5L121|uniprotkb:A0A384LBT1|uniprotkb:Q7ARJ5|uniprotkb:A0A2S9PEG7|uniprotkb:A0A5P8YM58	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:o68704_yerpe(display_long)|uniprotkb:yopK(gene name)|psi-mi:yopK(display_short)|uniprotkb:yopQ(gene name synonym)|uniprotkb:Y0066(gene name synonym)|uniprotkb:YPCD1.19c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817030|imex:IM-26497-684	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	"go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|refseq:NP_395154.1|refseq:NP_857759.1|refseq:NP_857959.1|refseq:WP_002213007.1|interpro:IPR016505(Type III secreted protein YopQ)|mint:O68704"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:v8uTxKoDAiSSSQ1kseuCf0e8QgE632	intact-crc:5A1B507368958931|rigid:hKaQ+wlVE2w/830KRaa/SPKSFyA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UI14	uniprotkb:O68703	intact:EBI-712367|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1|ensembl:ENSP00000222008.5	intact:EBI-20817042	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:yopt_yerpe(display_long)|uniprotkb:yopT(gene name)|psi-mi:yopT(display_short)|uniprotkb:YPCD1.20(locus name)|uniprotkb:y5059(locus name)|uniprotkb:y0065(locus name)|uniprotkb:YP_pCD67(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817060|imex:IM-26497-422	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006414.2|ensembl:ENSG00000105404.11(gene)|ensembl:ENST00000222008.11(transcript)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0051020""(GTPase binding)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|panther:PTHR19317(orthology-group)"	"mint:O68703|refseq:NP_395155.1|refseq:NP_857758.1|refseq:NP_857958.1|refseq:WP_002213006.1|interpro:IPR038765|interpro:IPR003951(Peptidase C58, Yersinia/Haemophilus virulence surface antigen)|interpro:IPR006473(Peptidase C58, yopT)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:Ad5U2DWO67mf3ky3TfJu4C9RBA0632	intact-crc:8B18003ED9275088|rigid:FQYXHZ5/9vwezeHEKidGdGzUP/w	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:Q9ZGW6	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20817066	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:syct_yerpe(display_long)|uniprotkb:sycT(gene name)|psi-mi:sycT(display_short)|uniprotkb:YPCD1.21(locus name)|uniprotkb:y5058(locus name)|uniprotkb:y0064(locus name)|uniprotkb:YP_pCD66(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817080|imex:IM-26497-742	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"mint:Q9ZGW6|refseq:NP_395156.1|refseq:NP_857957.1|refseq:WP_002213004.1|interpro:IPR010261(Tir chaperone)|go:""GO:0030254""(protein secretion by the type III secretion system)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:WVrSA98bDkiXT2u6mpIJKrWPA0U632	intact-crc:E1DED455D8ABBE3E|rigid:YkpEUlUiQv350w43PNBG36+mN2Q	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P16144	uniprotkb:Q9ZGW6	intact:EBI-948678|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97|ensembl:ENSP00000200181.3	intact:EBI-20817066	psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short)	psi-mi:syct_yerpe(display_long)|uniprotkb:sycT(gene name)|psi-mi:sycT(display_short)|uniprotkb:YPCD1.21(locus name)|uniprotkb:y5058(locus name)|uniprotkb:y0064(locus name)|uniprotkb:YP_pCD66(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817086|imex:IM-26497-582	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-40182N|efo:""Orphanet:1114""|efo:""Orphanet:158684""|efo:""Orphanet:251393""|efo:""Orphanet:79402""|efo:""Orphanet:79403""|ensembl:ENSG00000132470.14(gene)|ensembl:ENST00000200181.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006914""(autophagy)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009611""(response to wounding)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030054""(cell junction)|go:""GO:0030056""(hemidesmosome)|go:""GO:0031252""(cell leading edge)|go:""GO:0031581""(hemidesmosome assembly)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032290""(peripheral nervous system myelin formation)|go:""GO:0035878""(nail development)|go:""GO:0043235""(receptor complex)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0046847""(filopodium assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048870""(cell motility)|go:""GO:0061450""(trophoblast cell migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|reactome:R-HSA-9725554|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1|panther:PTHR10082(orthology-group)"	"mint:Q9ZGW6|refseq:NP_395156.1|refseq:NP_857957.1|refseq:WP_002213004.1|interpro:IPR010261(Tir chaperone)|go:""GO:0030254""(protein secretion by the type III secretion system)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/01/24	rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606	rogid:WVrSA98bDkiXT2u6mpIJKrWPA0U632	intact-crc:6B6800FA2A2AA666|rigid:kff2nHUU70HISTeyH554A98fcjQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P46379	uniprotkb:O68699	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2863258|uniprotkb:Q74YX3|uniprotkb:Q7ARJ1|uniprotkb:A0A0H2W168|uniprotkb:A0A380SDE6|uniprotkb:A0A2S9PED1	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:o68699_yerpe(display_long)|uniprotkb:yopD(gene name)|psi-mi:yopD(display_short)|uniprotkb:Y0053(gene name synonym)|uniprotkb:YPCD1.28c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817092|imex:IM-26497-424	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	refseq:NP_857754.1|refseq:NP_857949.1|interpro:IPR008898(YopD)|refseq:NP_395162.1|mint:O68699|refseq:WP_002212987.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:wIJgJUGGHZSulW8aNQiZGgZyrc4632	intact-crc:B1D1FE338D9DC8CA|rigid:Ktog9cPVyUrPuOZKxaRtbl6fi0k	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NXV2	uniprotkb:P69955	intact:EBI-1056857|uniprotkb:D3DU96|ensembl:ENSP00000301738.4	intact:EBI-2869506|uniprotkb:Q663K6|uniprotkb:P31487|uniprotkb:Q56976	psi-mi:kctd5_human(display_long)|uniprotkb:KCTD5(gene name)|psi-mi:KCTD5(display_short)	psi-mi:lcrd_yerpe(display_long)|uniprotkb:lcrD(gene name)|psi-mi:lcrD(display_short)|uniprotkb:YPCD1.34c(locus name)|uniprotkb:y5044(locus name)|uniprotkb:y0047(locus name)|uniprotkb:YP_pCD49(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817122|imex:IM-26497-524	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_061865.1|ensembl:ENSG00000167977.9(gene)|ensembl:ENST00000301738.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0097602""(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q9NXV2|rcsb pdb:3DRX|rcsb pdb:3DRY|rcsb pdb:3DRZ|rcsb pdb:8U7Z|rcsb pdb:8U80|rcsb pdb:8U81|rcsb pdb:8U82|rcsb pdb:8U83|rcsb pdb:8U84|panther:PTHR14958(orthology-group)"	"interpro:IPR042193|interpro:IPR042194|interpro:IPR042196|refseq:NP_395168.1|refseq:NP_857748.1|refseq:NP_857943.1|interpro:IPR001712(Type III secretion system FHIPEP)|interpro:IPR006302(Type III secretion protein HrcV)|interpro:IPR025505|refseq:WP_002212971.1|mint:P69955|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|panther:PTHR30161(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:KzXA4jgTKUY/EE1ORX+nMLCPfro9606	rogid:rl4HwZ4Omc0YS+FLax8Y+fsuI5E632	intact-crc:7E6135337B1D7E48|rigid:n+gXMDkAeQhucuRH0/QtVPCAn5U	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q16799	uniprotkb:O68698	intact:EBI-742130|uniprotkb:Q16800|uniprotkb:Q16801|uniprotkb:Q5BKZ4|intact:EBI-2801527|uniprotkb:Q9BQ59|ensembl:ENSP00000267484.5	intact:EBI-20817098|uniprotkb:A0A2U2GWD9|uniprotkb:A0A0H2W063|uniprotkb:Q74YX4|uniprotkb:Q7ARJ0|uniprotkb:A0A384KVL0|uniprotkb:A0A380SCR5	psi-mi:rtn1_human(display_long)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)	psi-mi:o68698_yerpe(display_long)|uniprotkb:yopB(gene name)|psi-mi:yopB(display_short)|uniprotkb:Y0052(gene name synonym)|uniprotkb:YPCD1.29c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817116|imex:IM-26497-386	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066959.1|refseq:NP_996734.1|ensembl:ENSG00000139970.18(gene)|ensembl:ENST00000267484.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007420""(brain development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030425""(dendrite)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0071787""(endoplasmic reticulum tubular network formation)|go:""GO:1902430""(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|interpro:IPR046964|mint:Q16799|panther:PTHR45799(orthology-group)"	"mint:O68698|refseq:NP_395163.1|refseq:NP_857753.1|refseq:NP_857948.1|refseq:WP_002212985.1|interpro:IPR006972(""Secretion system effector C (SseC) like protein"")|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:oBpsOfx4vuPEjlUg5McyYDfqKzo9606	rogid:R1Z4CvUk+wgb7Wv6WS5up1v8kYw632	intact-crc:F571ECBE5FFAEFDE|rigid:MS4Mc2Ueim7GPlnBB7aY04Y1Nu4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BZL4	uniprotkb:P61417	intact:EBI-721802|uniprotkb:Q59FK8|uniprotkb:Q6ZPD1|uniprotkb:Q7L8F7|uniprotkb:Q9H5H5|uniprotkb:Q9NT00|uniprotkb:Q96HW1|uniprotkb:B4DME2|ensembl:ENSP00000263433.1	intact:EBI-20592244|uniprotkb:P21209	psi-mi:pp12c_human(display_long)|uniprotkb:LENG3(gene name synonym)|uniprotkb:MBS85(gene name synonym)|uniprotkb:Protein phosphatase 1 myosin-binding subunit of 85 kDa(gene name synonym)|uniprotkb:PPP1R12C(gene name)|psi-mi:PPP1R12C(display_short)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817158|imex:IM-26497-426	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060077.1|refseq:NP_001258547.1|refseq:XP_005259070.1|ensembl:ENSG00000125503.13(gene)|ensembl:ENST00000263433.8(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0007165""(signal transduction)|go:""GO:0017020""(myosin phosphatase regulator activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0048812""(neuron projection morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR031775|interpro:IPR036770|interpro:IPR051226|mint:Q9BZL4|panther:PTHR24179(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:q24mbt02IydCWtQyNXmNVWav/i89606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:0C6196FF2CED1A27|rigid:xpQBD+2F54tvgW4QmT8AAtAVtYo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13573	uniprotkb:P69955	intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531.8	intact:EBI-2869506|uniprotkb:Q663K6|uniprotkb:P31487|uniprotkb:Q56976	psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short)	psi-mi:lcrd_yerpe(display_long)|uniprotkb:lcrD(gene name)|psi-mi:lcrD(display_short)|uniprotkb:YPCD1.34c(locus name)|uniprotkb:y5044(locus name)|uniprotkb:y0047(locus name)|uniprotkb:YP_pCD49(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817134|imex:IM-26497-584	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036377.1|ensembl:ENSG00000100603.14(gene)|ensembl:ENST00000261531.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005112""(Notch binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016604""(nuclear body)|go:""GO:0016607""(nuclear speck)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0048385""(regulation of retinoic acid receptor signaling pathway)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0070562""(regulation of vitamin D receptor signaling pathway)|go:""GO:0070564""(positive regulation of vitamin D receptor signaling pathway)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071300""(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8RO2|rcsb pdb:9FMD|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|dip:DIP-34800N|panther:PTHR12096(orthology-group)"	"interpro:IPR042193|interpro:IPR042194|interpro:IPR042196|refseq:NP_395168.1|refseq:NP_857748.1|refseq:NP_857943.1|interpro:IPR001712(Type III secretion system FHIPEP)|interpro:IPR006302(Type III secretion protein HrcV)|interpro:IPR025505|refseq:WP_002212971.1|mint:P69955|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|panther:PTHR30161(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/21	rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606	rogid:rl4HwZ4Omc0YS+FLax8Y+fsuI5E632	intact-crc:C2E214E1E429CDC5|rigid:UjXwbmTALAU1mFh7CPQ2VgB2YaE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P28290	uniprotkb:P61417	intact:EBI-722905|uniprotkb:Q8N7H2|uniprotkb:Q7Z7L2|uniprotkb:Q8N1L3|uniprotkb:Q8N263|uniprotkb:Q8NEN5|uniprotkb:Q96E36|uniprotkb:Q68DA6|uniprotkb:Q96PW1|uniprotkb:A8K6T0|ensembl:ENSP00000388731.2|intact:EBI-28986959	intact:EBI-20592244|uniprotkb:P21209	psi-mi:itpi2_human(display_long)|uniprotkb:ITPRID2(gene name)|psi-mi:ITPRID2(display_short)|uniprotkb:CS1(gene name synonym)|uniprotkb:Cleavage signal-1 protein(gene name synonym)|uniprotkb:ITPR-interacting domain-containing protein 2(gene name synonym)|uniprotkb:KIAA1927(gene name synonym)|uniprotkb:KRAP(gene name synonym)|uniprotkb:Ki-ras-induced actin-interacting protein(gene name synonym)|uniprotkb:SSFA2(gene name synonym)|uniprotkb:Sperm-specific antigen 2(gene name synonym)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817164|imex:IM-26497-528	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123917.1|refseq:NP_006742.2|refseq:NP_001274432.1|refseq:NP_001274433.1|ensembl:ENSG00000138434.17(gene)|ensembl:ENST00000431877.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0051015""(actin filament binding)|interpro:IPR029325|interpro:IPR029326|interpro:IPR043444|mint:P28290|dip:DIP-47271N|panther:PTHR17469(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:oLYBDg++fr2C4VnIkkP5xhll5dw9606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:762D1659168D3338|rigid:jd45GKmhhVGqNkwrEuYdM8N6mpI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13137	uniprotkb:P61417	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5|ensembl:ENSP00000258947.3	intact:EBI-20592244|uniprotkb:P21209	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817146|imex:IM-26497-624	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|refseq:NP_001248324.1|ensembl:ENSG00000136436.16(gene)|ensembl:ENST00000258947.8(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005776""(autophagosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016032""(viral process)|go:""GO:0016605""(PML body)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034341""(response to type II interferon)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0098792""(xenophagy)|go:""GO:1901098""(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|interpro:IPR051002|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|rcsb pdb:7EAA|dip:DIP-57534N|panther:PTHR31915(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	crc64:609B121DA1A9DCB8	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/10	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:12DFD03B610B3525|rigid:rrCiEPjHimEGfJJNAA+BKcXshM8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P54259	uniprotkb:P61417	intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076.3|ensembl:ENSP00000379915.2	intact:EBI-20592244|uniprotkb:P21209	psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817140|imex:IM-26497-388	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111676.15(gene)|ensembl:ENST00000356654.8(transcript)|ensembl:ENST00000396684.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001906""(cell killing)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008584""(male gonad development)|go:""GO:0009791""(post-embryonic development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0032094""(response to food)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0070161""(anchoring junction)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724|refseq:NP_001007027.1|refseq:NP_001931.2|dip:DIP-29423N|efo:""Orphanet:101""|panther:PTHR13859(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	crc64:B47603486C672637	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/01/27	rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:C7E0572D283434EF|rigid:uDBTsAcR9Rx/3BZjVGgYyFnp35U	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q06323	uniprotkb:P69955	intact:EBI-712149|uniprotkb:H0YNE3|uniprotkb:Q9UEF4|ensembl:ENSP00000206451.6|ensembl:ENSP00000495095.1|uniprotkb:Q6IBM2|uniprotkb:A6NJG9	intact:EBI-2869506|uniprotkb:Q663K6|uniprotkb:P31487|uniprotkb:Q56976	psi-mi:psme1_human(display_long)|uniprotkb:Proteasome activator 28 subunit alpha(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 1(gene name synonym)|uniprotkb:11S regulator complex subunit alpha(gene name synonym)|uniprotkb:Interferon gamma up-regulated I-5111 protein(gene name synonym)|uniprotkb:PSME1(gene name)|psi-mi:PSME1(display_short)|uniprotkb:IFI5111(gene name synonym)	psi-mi:lcrd_yerpe(display_long)|uniprotkb:lcrD(gene name)|psi-mi:lcrD(display_short)|uniprotkb:YPCD1.34c(locus name)|uniprotkb:y5044(locus name)|uniprotkb:y0047(locus name)|uniprotkb:YP_pCD49(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817128|imex:IM-26497-526	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006254.1|ensembl:ENSG00000092010.15(gene)|ensembl:ENSG00000284916.2(gene)|ensembl:ENST00000206451.11(transcript)|ensembl:ENST00000645537.2(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008537""(proteasome activator complex)|go:""GO:0019884""(antigen processing and presentation of exogenous antigen)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q06323|rcsb pdb:1AVO|rcsb pdb:7DR6|rcsb pdb:7DRW|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:8CXB|reactome:R-HSA-9907900|refseq:NP_001268457.1|panther:PTHR10660(orthology-group)"	"interpro:IPR042193|interpro:IPR042194|interpro:IPR042196|refseq:NP_395168.1|refseq:NP_857748.1|refseq:NP_857943.1|interpro:IPR001712(Type III secretion system FHIPEP)|interpro:IPR006302(Type III secretion protein HrcV)|interpro:IPR025505|refseq:WP_002212971.1|mint:P69955|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|panther:PTHR30161(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:kyTjI3VP2S7Bvwq4R0pJudnlOC09606	rogid:rl4HwZ4Omc0YS+FLax8Y+fsuI5E632	intact-crc:05D56254BD9278CF|rigid:4o6NZvcUWd1JWnIKIY0LrUy6hjw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05783	uniprotkb:P61417	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	intact:EBI-20592244|uniprotkb:P21209	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817152|imex:IM-26497-484	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:4F66BCCDBFD1F7D0|rigid:RlF3uennZNdw/I0NAyrMoDpX24w	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P04792	uniprotkb:P61417	intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|uniprotkb:B2R4N8|ensembl:ENSP00000248553.6	intact:EBI-20592244|uniprotkb:P21209	psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym)|uniprotkb:Heat shock protein family B member 1(gene name synonym)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817182|imex:IM-26497-744	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106211.11(gene)|ensembl:ENST00000248553.7(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001533""(cornified envelope)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008426""(protein kinase C inhibitor activity)|go:""GO:0009408""(response to heat)|go:""GO:0009615""(response to virus)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042026""(protein refolding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1904115""(axon cytoplasm)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|refseq:NP_001531.1|efo:""Orphanet:139525""|efo:""Orphanet:99940""|dip:DIP-412N|panther:PTHR45640(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	crc64:1B4DC44A6F6606D5	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:CE44E4B22179B0E3|rigid:GdBhAg0ow1ZkfGqBNrOtKKaMNa8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O60504	uniprotkb:P61417	intact:EBI-741237|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4|ensembl:ENSP00000240123.7	intact:EBI-20592244|uniprotkb:P21209	psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817176|imex:IM-26497-486	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1|ensembl:ENSG00000120896.14(gene)|ensembl:ENST00000240123.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0017166""(vinculin binding)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0051495""(positive regulation of cytoskeleton organization)|go:""GO:0051496""(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|interpro:IPR050384|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|panther:PTHR14167(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:BF4E645460180C33|rigid:ezqES2bZQwvlRtnqnp85OJGEDH4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P12814	uniprotkb:P61417	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403.6	intact:EBI-20592244|uniprotkb:P21209	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817170|imex:IM-26497-390	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:140957""|ensembl:ENSG00000072110.17(gene)|ensembl:ENST00000193403.11(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007015""(actin filament organization)|go:""GO:0017166""(vinculin binding)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030220""(platelet formation)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031143""(pseudopodium)|go:""GO:0036344""(platelet morphogenesis)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0042995""(cell projection)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051639""(actin filament network formation)|go:""GO:0055001""(muscle cell development)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099186""(structural constituent of postsynapse)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034|refseq:NP_001093.1|refseq:NP_001123476.1|refseq:NP_001123477.1|dip:DIP-33184N|panther:PTHR11915(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:D2039357F75A787C|rigid:nA6/B0LbAiqbqCsF4bN8/Mgr3aU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q12805	uniprotkb:P61416	intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|uniprotkb:B4DW75|ensembl:ENSP00000347596.3|ensembl:ENSP00000378058.2	intact:EBI-20817212|uniprotkb:O68696	psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817227|imex:IM-26497-626	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24039(orthology-group)|ensembl:ENSG00000115380.20(gene)|ensembl:ENST00000355426.8(transcript)|ensembl:ENST00000394555.6(transcript)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007601""(visual perception)|go:""GO:0008083""(growth factor activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0043010""(camera-type eye development)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1|efo:""Orphanet:75376""|efo:""Orphanet:98977"""	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:7D4CD17AF918B93C|rigid:mdjgbft/DCMDY6gwaTUkmx0YNJY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P28799	uniprotkb:P61417	intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|uniprotkb:Q53Y88|uniprotkb:Q540U8|ensembl:ENSP00000053867.2|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1	intact:EBI-20592244|uniprotkb:P21209	psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817200|imex:IM-26497-488	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314629""|ensembl:ENSG00000030582.19(gene)|ensembl:ENST00000053867.8(transcript)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0002282""(microglial cell activation involved in immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0007040""(lysosome organization)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0007165""(signal transduction)|go:""GO:0008083""(growth factor activity)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0060266""(negative regulation of respiratory burst involved in inflammatory response)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106016""(positive regulation of inflammatory response to wounding)|go:""GO:1900426""(positive regulation of defense response to bacterium)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1903334""(positive regulation of protein folding)|go:""GO:1903979""(negative regulation of microglial cell activation)|go:""GO:1905247""(positive regulation of aspartic-type peptidase activity)|go:""GO:1905673""(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|rcsb pdb:8T8R|rcsb pdb:8T8S|reactome:R-HSA-6798695|refseq:NP_002078.1|refseq:XP_005257310.1|dip:DIP-41742N|efo:""Orphanet:100069""|efo:""Orphanet:100070""|efo:""Orphanet:275864""|panther:PTHR12274(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/27	rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:B0C6AF230E3DDF0B|rigid:5XwOLTRXGk6h2Z+yiGx1kwm9xqU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O15162	uniprotkb:P61417	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	intact:EBI-20592244|uniprotkb:P21209	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817206|imex:IM-26497-686	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:AA1DFB2799D74041|rigid:XDB8J41aYSXNZc/UsNz/HatDMls	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O14964	uniprotkb:P61416	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201.4|ensembl:ENSP00000504106.1	intact:EBI-20817212|uniprotkb:O68696	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817239|imex:IM-26497-586	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004703.1|ensembl:ENSG00000185359.14(gene)|ensembl:ENST00000329138.9(transcript)|ensembl:ENST00000676546.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010324""(membrane invagination)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010642""(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:""GO:0016197""(endosomal transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033565""(ESCRT-0 complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0042176""(regulation of protein catabolic process)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043405""(regulation of MAP kinase activity)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0090148""(membrane fission)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:1903543""(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|dip:DIP-29050N|panther:PTHR46275(orthology-group)"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/27	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:4C072D0ACE625BE9|rigid:cPLFxaVnJ7kU/p4K7Li9sySI+yg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:P61417	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20592244|uniprotkb:P21209	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817188|imex:IM-26497-428	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:E2AD41E71F362048|rigid:QSK4mveEnUvCWvu8e9GIRtd3SL0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14764	uniprotkb:P61417	intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977.5|ensembl:ENSP00000378760.1	intact:EBI-20592244|uniprotkb:P21209	psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym)	psi-mi:yscy_yerpe(display_long)|uniprotkb:yscY(gene name)|psi-mi:yscY(display_short)|uniprotkb:Yop proteins translocation protein Y(gene name synonym)|uniprotkb:YPCD1.35c(locus name)|uniprotkb:YP_pCD48(locus name)|uniprotkb:y0046(locus name)|uniprotkb:y5043(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817194|imex:IM-26497-530	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364.19(gene)|ensembl:ENST00000357402.10(transcript)|ensembl:ENST00000395353.5(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0008283""(cell population proliferation)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031953""(negative regulation of protein autophosphorylation)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051028""(mRNA transport)|go:""GO:0061099""(negative regulation of protein tyrosine kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072376""(protein activation cascade)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695|refseq:NP_001280133.1|refseq:NP_001280134.1|panther:PTHR14165(orthology-group)"	"go:""GO:0005737""(cytoplasm)|interpro:IPR016684(Type III secretion system chaperone, YscY)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_395169.1|refseq:NP_857747.1|refseq:NP_857942.1|refseq:WP_002229791.1|mint:P61417"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606	rogid:NG8XAy+y7ivfKSWWeiU+/MeE+R4632	intact-crc:CFCA15D902AA4381|rigid:mN9AdqQKgD9CTcseISbzXIWDnNw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:P61416	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20817212|uniprotkb:O68696	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817233|imex:IM-26497-746	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:2943E15C7AE09D2F|rigid:x5ACwtjOCCbwmKFGEeJPKpPNTLI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P61289	uniprotkb:P61416	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794.1|intact:EBI-21352060	intact:EBI-20817212|uniprotkb:O68696	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817245|imex:IM-26497-442	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467.12(gene)|ensembl:ENST00000590720.6(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0002039""(p53 binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008537""(proteasome activator complex)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|rcsb pdb:7YQC|rcsb pdb:7YQD|reactome:R-HSA-9907900|panther:PTHR10660(orthology-group)"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:A9A3E4FD86F88321|rigid:ZNRg36FhGIaINt1OvrHQ4bcvAoc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6PKC3	uniprotkb:P61416	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	intact:EBI-20817212|uniprotkb:O68696	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817257|imex:IM-26497-688	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:408A1E04C5C89133|rigid:BfXXMsvsVBvigvKfmFVYpTvQCG4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6UWE0	uniprotkb:P61416	intact:EBI-720984|uniprotkb:Q5VVV0|uniprotkb:Q8NB40|uniprotkb:Q96GT5|uniprotkb:Q96MX5|uniprotkb:Q96MZ7|ensembl:ENSP00000300417.6|ensembl:ENSP00000322937.4|ensembl:ENSP00000362419.1|ensembl:ENSP00000502167.1|intact:EBI-21356892	intact:EBI-20817212|uniprotkb:O68696	psi-mi:lrsm1_human(display_long)|uniprotkb:Leucine-rich repeat and sterile alpha motif-containing protein 1(gene name synonym)|uniprotkb:Tsg101-associated ligase(gene name synonym)|uniprotkb:LRSAM1(gene name)|psi-mi:LRSAM1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:UNQ6496/PRO21356(orf name)|uniprotkb:RING-type E3 ubiquitin transferase LRSAM1(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817263|imex:IM-26497-690	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:300319""|ensembl:ENSG00000148356.15(gene)|ensembl:ENST00000300417.11(transcript)|ensembl:ENST00000323301.8(transcript)|ensembl:ENST00000373322.1(transcript)|ensembl:ENST00000675448.1(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0016020""(membrane)|go:""GO:0030163""(protein catabolic process)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0046755""(viral budding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070086""(ubiquitin-dependent endocytosis)|go:""GO:1904417""(positive regulation of xenophagy)|go:""GO:2000786""(positive regulation of autophagosome assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032675|interpro:IPR050216|mint:Q6UWE0|reactome:R-HSA-983168|refseq:NP_001005373.1|refseq:NP_001005374.1|refseq:NP_001177652.1|refseq:NP_612370.3|refseq:XP_016870772.1|panther:PTHR16083(orthology-group)"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:qkwPqOsfNjZBB2Xp6YAA9FbEZxM9606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:EAC7D7AD07A65CCA|rigid:7mZO7wQnCvFMzj2j8pze3U+OXLs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5VU43	uniprotkb:P61416	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360.3|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	intact:EBI-20817212|uniprotkb:O68696	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817275|imex:IM-26497-444	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|ensembl:ENSG00000178104.22(gene)|ensembl:ENST00000369354.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0007098""(centrosome cycle)|go:""GO:0019899""(enzyme binding)|go:""GO:0030016""(myofibril)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|interpro:IPR052593|mint:Q5VU43|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|panther:PTHR46501(orthology-group)"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:2A99C0D1AC4DD8C0|rigid:PW0SzY20ZMRMlXZ+Yuv7Ua6T4MQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:P61416	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20817212|uniprotkb:O68696	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817293|imex:IM-26497-546	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:DCF664E30F3C1488|rigid:JL+O/HZrvZdYdWo/f5RSe2DhLjg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96EP0	uniprotkb:P61416	intact:EBI-948111|uniprotkb:Q9H5F1|uniprotkb:Q9NWD2|uniprotkb:Q86VI2|uniprotkb:Q8TEI0|uniprotkb:Q96GB4|uniprotkb:Q96NF1|uniprotkb:A0A962|ensembl:ENSP00000315112.6|ensembl:ENSP00000496609.1	intact:EBI-20817212|uniprotkb:O68696	psi-mi:rnf31_human(display_long)|uniprotkb:Zinc in-between-RING-finger ubiquitin-associated domain protein(gene name synonym)|uniprotkb:RNF31(gene name)|psi-mi:RNF31(display_short)|uniprotkb:ZIBRA(gene name synonym)|uniprotkb:HOIL-1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF31(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817251|imex:IM-26497-542	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:6KC5|rcsb pdb:6KC6|rcsb pdb:6SC5|rcsb pdb:6SC6|rcsb pdb:6SC7|rcsb pdb:6SC8|rcsb pdb:6SC9|rcsb pdb:7TV4|rcsb pdb:7UY2|rcsb pdb:7UYJ|rcsb pdb:7UYK|rcsb pdb:7V8F|rcsb pdb:7V8G|rcsb pdb:9AZJ|rcsb pdb:9B0B|rcsb pdb:9B0Z|rcsb pdb:9B12|reactome:R-HSA-5357786|ensembl:ENSG00000092098.18(gene)|ensembl:ENSG00000285152.2(gene)|ensembl:ENST00000324103.11(transcript)|ensembl:ENST00000647495.2(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0036435""(K48-linked polyubiquitin modification-dependent protein binding)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0071797""(LUBAC complex)|go:""GO:0097039""(protein linear polyubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:1904417""(positive regulation of xenophagy)|go:""GO:1990450""(linear polyubiquitin binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018997|interpro:IPR026254|interpro:IPR032065|interpro:IPR036339|interpro:IPR036443|interpro:IPR040641|interpro:IPR041031|interpro:IPR044066|interpro:IPR047539|interpro:IPR047540|interpro:IPR047541|interpro:IPR047542|interpro:IPR047543|mint:Q96EP0|rcsb pdb:2CT7|rcsb pdb:4DBG|rcsb pdb:4JUY|rcsb pdb:4LJO|rcsb pdb:4LJP|rcsb pdb:4LJQ|rcsb pdb:4OWF|rcsb pdb:4OYJ|rcsb pdb:4OYK|rcsb pdb:4P09|rcsb pdb:4P0A|rcsb pdb:4P0B|rcsb pdb:5EDV|rcsb pdb:5LJN|rcsb pdb:5X0W|rcsb pdb:6GZY|reactome:R-HSA-5357905|reactome:R-HSA-5357956|refseq:NP_001297261.1|refseq:NP_060469.4|dip:DIP-44034N|efo:""Orphanet:329173""|panther:PTHR16004(orthology-group)"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:5QylozByg2G8/5LnkorkdY5fPec9606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:637F6B4D645E9AAE|rigid:yPsPW1XEhO4uvWz65V0/kbvRG/k	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TD31	uniprotkb:P61416	intact:EBI-949834|uniprotkb:Q9NRK8|uniprotkb:Q9NWY9|uniprotkb:Q9NXJ4|uniprotkb:Q9NXK3|uniprotkb:Q9Y6W1|uniprotkb:Q9Y6W2|uniprotkb:Q5SQ82|uniprotkb:Q5STE9|uniprotkb:A2ABH6|uniprotkb:Q2TB67|uniprotkb:E9PE84|ensembl:ENSP00000365442.5|ensembl:ENSP00000372832.4|ensembl:ENSP00000373019.4|ensembl:ENSP00000383205.3|ensembl:ENSP00000393042.2|ensembl:ENSP00000408012.2	intact:EBI-20817212|uniprotkb:O68696	psi-mi:cchcr_human(display_long)|uniprotkb:Alpha-helical coiled-coil rod protein(gene name synonym)|uniprotkb:Putative gene 8 protein(gene name synonym)|uniprotkb:CCHCR1(gene name)|psi-mi:CCHCR1(display_short)|uniprotkb:C6orf18(gene name synonym)|uniprotkb:HCR(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817269|imex:IM-26497-628	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001099033.1|refseq:NP_001099034.1|refseq:NP_061925.2|refseq:XP_011513005.1|refseq:XP_016866451.1|refseq:XP_016866452.1|refseq:XP_016866453.1|refseq:XP_016866454.1|refseq:XP_016866455.1|refseq:XP_016866456.1|refseq:XP_016866457.1|dip:DIP-40394N|ensembl:ENSG00000204536.15(gene)|ensembl:ENSG00000206355.11(gene)|ensembl:ENSG00000206457.10(gene)|ensembl:ENSG00000234114.8(gene)|ensembl:ENST00000376266.9(transcript)|ensembl:ENST00000383341.8(transcript)|ensembl:ENST00000383527.8(transcript)|ensembl:ENST00000400352.7(transcript)|ensembl:ENST00000416163.6(transcript)|ensembl:ENST00000425620.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0030154""(cell differentiation)|go:""GO:0042802""(identical protein binding)|interpro:IPR009800(Alpha helical coiled-coil rod)|mint:Q8TD31|panther:PTHR46822(orthology-group)"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/01/27	rogid:wgzA1VMrSlj7h29Hpmg5L0IOAJU9606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:1598DC107E82C91E|rigid:BBLv1EE5pFf8L94P+nOTVlHlcVc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05783	uniprotkb:P61416	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	intact:EBI-20817212|uniprotkb:O68696	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817281|imex:IM-26497-392	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:713D99C9AFDBC310|rigid:CNP7sfKntn1iNmCMafgzseqlFFg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99816	uniprotkb:P61416	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968.3	intact:EBI-20817212|uniprotkb:O68696	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:yscx_yerpe(display_long)|uniprotkb:yscX(gene name)|psi-mi:yscX(display_short)|uniprotkb:YPCD1.36c(locus name)|uniprotkb:y5042(locus name)|uniprotkb:y0045(locus name)|uniprotkb:YP_pCD47(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817287|imex:IM-26497-544	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006283.1|dip:DIP-31809N|panther:PTHR23306(orthology-group)|rcsb pdb:1M4P|ensembl:ENSG00000074319.13(gene)|ensembl:ENST00000251968.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000813""(ESCRT I complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006858""(extracellular transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0019076""(viral release from host cell)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0036211""(protein modification process)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043405""(regulation of MAP kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046755""(viral budding)|go:""GO:0046790""(virion binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0051301""(cell division)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090148""(membrane fission)|go:""GO:0090543""(Flemming body)|go:""GO:0097352""(autophagosome maturation)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903551""(regulation of extracellular exosome assembly)|go:""GO:1903774""(positive regulation of viral budding via host ESCRT complex)|go:""GO:1990182""(exosomal secretion)|go:""GO:2000397""(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|interpro:IPR052070|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|rcsb pdb:7NLC|rcsb pdb:7ZLX|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710"	"mint:P61416|refseq:NP_857941.1|refseq:NP_395170.1|refseq:NP_857746.1|refseq:WP_002212969.1|interpro:IPR012672(Type III secretion system YscX)|go:""GO:0005576""(extracellular region)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:ZyyICdyyTSj/3G4GhPJnpwtIlZQ632	intact-crc:4ACB102343A47438|rigid:ocvwjE9Dbp6v5iMK5tuo+IXjqcg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BR76	uniprotkb:P69968	intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211.5|ensembl:ENSP00000377471.1	intact:EBI-20817299|uniprotkb:P16161|uniprotkb:Q663K2	psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:tyea_yerpe(display_long)|uniprotkb:YPCD1.38c(locus name)|uniprotkb:y5040(locus name)|uniprotkb:y0043(locus name)|uniprotkb:YP_pCD45(locus name)|uniprotkb:tyeA(gene name)|psi-mi:tyeA(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817359|imex:IM-26497-694	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725.14(gene)|ensembl:ENST00000341356.10(transcript)|ensembl:ENST00000393893.5(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007015""(actin filament organization)|go:""GO:0016477""(cell migration)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031529""(ruffle organization)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0034316""(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0035767""(endothelial cell chemotaxis)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071672""(negative regulation of smooth muscle cell chemotaxis)|go:""GO:0071933""(Arp2/3 complex binding)|go:""GO:0071944""(cell periphery)|go:""GO:0090135""(actin filament branching)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1902463""(protein localization to cell leading edge)|go:""GO:2000394""(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BR76|dip:DIP-33176N|panther:PTHR10856(orthology-group)"	mint:P69968|refseq:NP_395172.1|refseq:NP_857744.1|refseq:NP_857939.1|refseq:WP_002212965.1|interpro:IPR015144(TyeA)|interpro:IPR013351(Type III secretion system effector delivery regulator TyeA)|interpro:IPR038347|rcsb pdb:1XL3	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/05	rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606	rogid:zI9wEJBIrVcC8DxDaY7ODlj1bH8632	intact-crc:C13ABA09520A66A0|rigid:D5Xfep+PXDFOPIgMNDg2dpgE6a0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UNH7	uniprotkb:P69968	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	intact:EBI-20817299|uniprotkb:P16161|uniprotkb:Q663K2	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	psi-mi:tyea_yerpe(display_long)|uniprotkb:YPCD1.38c(locus name)|uniprotkb:y5040(locus name)|uniprotkb:y0043(locus name)|uniprotkb:YP_pCD45(locus name)|uniprotkb:tyeA(gene name)|psi-mi:tyeA(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817341|imex:IM-26497-634	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	mint:P69968|refseq:NP_395172.1|refseq:NP_857744.1|refseq:NP_857939.1|refseq:WP_002212965.1|interpro:IPR015144(TyeA)|interpro:IPR013351(Type III secretion system effector delivery regulator TyeA)|interpro:IPR038347|rcsb pdb:1XL3	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/17	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	rogid:zI9wEJBIrVcC8DxDaY7ODlj1bH8632	intact-crc:61481B8271B08485|rigid:af17o5nNJUQrC2toEkqxNhEWw20	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BS26	uniprotkb:P69968	intact:EBI-541644|uniprotkb:O60319|uniprotkb:Q5VWZ7|uniprotkb:Q6UW14|uniprotkb:Q8WX67|intact:EBI-1054855|uniprotkb:Q4VXC1|ensembl:ENSP00000262455.6	intact:EBI-20817299|uniprotkb:P16161|uniprotkb:Q663K2	psi-mi:erp44_human(display_long)|uniprotkb:ERP44(gene name)|psi-mi:ERP44(display_short)|uniprotkb:UNQ532/PRO1075(orf name)|uniprotkb:TXNDC4(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 4(gene name synonym)|uniprotkb:KIAA0573(gene name synonym)	psi-mi:tyea_yerpe(display_long)|uniprotkb:YPCD1.38c(locus name)|uniprotkb:y5040(locus name)|uniprotkb:y0043(locus name)|uniprotkb:YP_pCD45(locus name)|uniprotkb:tyeA(gene name)|psi-mi:tyeA(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817347|imex:IM-26497-642	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055866.1|ensembl:ENSG00000023318.9(gene)|ensembl:ENST00000262455.7(transcript)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0009100""(glycoprotein metabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035580""(specific granule lumen)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041862|interpro:IPR041870|interpro:IPR052643|mint:Q9BS26|rcsb pdb:2R2J|rcsb pdb:5GU6|rcsb pdb:5GU7|rcsb pdb:5HQP|rcsb pdb:5XWM|reactome:R-HSA-6798695|panther:PTHR46295(orthology-group)"	mint:P69968|refseq:NP_395172.1|refseq:NP_857744.1|refseq:NP_857939.1|refseq:WP_002212965.1|interpro:IPR015144(TyeA)|interpro:IPR013351(Type III secretion system effector delivery regulator TyeA)|interpro:IPR038347|rcsb pdb:1XL3	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:TpwaFRifveb03iRPS2pEZve1kLA9606	rogid:zI9wEJBIrVcC8DxDaY7ODlj1bH8632	intact-crc:1E506DB6A46F568F|rigid:SIF/3rRGt1kAcW4IXvf1pQ5pCwc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99814	uniprotkb:P69968	intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734.3	intact:EBI-20817299|uniprotkb:P16161|uniprotkb:Q663K2	psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym)	psi-mi:tyea_yerpe(display_long)|uniprotkb:YPCD1.38c(locus name)|uniprotkb:y5040(locus name)|uniprotkb:y0043(locus name)|uniprotkb:YP_pCD45(locus name)|uniprotkb:tyeA(gene name)|psi-mi:tyeA(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817329|imex:IM-26497-632	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000116016.14(gene)|ensembl:ENST00000263734.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001525""(angiogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0002070""(epithelial cell maturation)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0016607""(nuclear speck)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030324""(lung development)|go:""GO:0042415""(norepinephrine metabolic process)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0043129""(surfactant homeostasis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048625""(myoblast fate commitment)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|rcsb pdb:7Q5V|rcsb pdb:7Q5X|rcsb pdb:7UJV|rcsb pdb:8CK3|rcsb pdb:8CK4|rcsb pdb:8CK8|rcsb pdb:8Q5S|rcsb pdb:8Q64|rcsb pdb:8Q6D|rcsb pdb:8Q6E|reactome:R-HSA-1234158|reactome:R-HSA-1234174|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|refseq:NP_001421.2|efo:""Orphanet:247511""|efo:""Orphanet:276621""|efo:""Orphanet:324299""|dip:DIP-32857N|panther:PTHR23043(orthology-group)"	mint:P69968|refseq:NP_395172.1|refseq:NP_857744.1|refseq:NP_857939.1|refseq:WP_002212965.1|interpro:IPR015144(TyeA)|interpro:IPR013351(Type III secretion system effector delivery regulator TyeA)|interpro:IPR038347|rcsb pdb:1XL3	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606	rogid:zI9wEJBIrVcC8DxDaY7ODlj1bH8632	intact-crc:34BB25172F73BBA5|rigid:EaV2IsCD/1tVBJE61gv7akVdWzc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H0C5	uniprotkb:P68640	intact:EBI-935503|uniprotkb:A6NMI8|uniprotkb:Q9BX71|uniprotkb:Q9NWN4|ensembl:ENSP00000261721.4	intact:EBI-20817365|uniprotkb:P16160	psi-mi:btbd1_human(display_long)|uniprotkb:BTBD1(gene name)|psi-mi:BTBD1(display_short)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 8(gene name synonym)|uniprotkb:NS5ATP8(gene name synonym)	psi-mi:yopn_yerpe(display_long)|uniprotkb:yopN(gene name)|psi-mi:yopN(display_short)|uniprotkb:lcrE(gene name synonym)|uniprotkb:YPCD1.39c(locus name)|uniprotkb:y5039(locus name)|uniprotkb:y0042(locus name)|uniprotkb:YP_pCD44(locus name)|uniprotkb:LcrE(gene name synonym)|uniprotkb:Yop4b(gene name synonym)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817388|imex:IM-26497-394	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001011885.1|refseq:NP_079514.1|ensembl:ENSG00000064726.10(gene)|ensembl:ENST00000261721.9(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007517""(muscle organ development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0022008""(neurogenesis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:0043393""(regulation of protein binding)|go:""GO:0097602""(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR012983(PHR)|interpro:IPR038648|mint:Q9H0C5|reactome:R-HSA-8951664|reactome:R-HSA-983168|panther:PTHR45774(orthology-group)"	"mint:P68640|refseq:NP_857743.1|refseq:NP_857938.1|refseq:NP_395173.1|refseq:WP_002212958.1|interpro:IPR010812(Hypersensitivity response secretion HrpJ)|interpro:IPR013401(Type III secretion regulator, YopN/LcrE/InvE/MxiC)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0050709""(negative regulation of protein secretion)|rcsb pdb:1XKP|rcsb pdb:1XL3"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:fRSh7JVRI2O2o8m7WCEjydcX1QM9606	rogid:MKix/cQFqtaeWtEMcnieRrRgypM632	intact-crc:0B0383F7EB867E66|rigid:1R/EAov27QXilhFr7zE0sMWYu2M	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P15880	uniprotkb:P69968	intact:EBI-443446|ensembl:ENSP00000341885.4|ensembl:ENSP00000517575.1|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82	intact:EBI-20817299|uniprotkb:P16161|uniprotkb:Q663K2	psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:40S ribosomal protein S2(gene name synonym)	psi-mi:tyea_yerpe(display_long)|uniprotkb:YPCD1.38c(locus name)|uniprotkb:y5040(locus name)|uniprotkb:y0043(locus name)|uniprotkb:YP_pCD45(locus name)|uniprotkb:tyeA(gene name)|psi-mi:tyeA(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817317|imex:IM-26497-630	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000140988.16(gene)|ensembl:ENSG00000291931.1(gene)|ensembl:ENST00000343262.9(transcript)|ensembl:ENST00000709238.1(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0016020""(membrane)|go:""GO:0017134""(fibroblast growth factor binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0045296""(cadherin binding)|go:""GO:0051443""(positive regulation of ubiquitin-protein transferase activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7QVP|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7WTV|rcsb pdb:7WTW|rcsb pdb:7WTX|rcsb pdb:7WTZ|rcsb pdb:7WU0|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9735869|reactome:R-HSA-9754678|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002943.2|panther:PTHR13718(orthology-group)|ensembl:ENSP00000341885.4|ensembl:ENSP00000517575.1"	mint:P69968|refseq:NP_395172.1|refseq:NP_857744.1|refseq:NP_857939.1|refseq:WP_002212965.1|interpro:IPR015144(TyeA)|interpro:IPR013351(Type III secretion system effector delivery regulator TyeA)|interpro:IPR038347|rcsb pdb:1XL3	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606	rogid:zI9wEJBIrVcC8DxDaY7ODlj1bH8632	intact-crc:D07E3285EA10E26D|rigid:8YKQlUz1tXVVqZsLTDG17aX+95k	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96PU8	uniprotkb:Q83A11	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094.3	intact:EBI-21286600	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)|uniprotkb:Protein quaking(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286691|imex:IM-26899-59	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000112531.17(gene)|ensembl:ENST00000361752.8(transcript)|go:""GO:0001570""(vasculogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007286""(spermatid development)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010717""(regulation of epithelial to mesenchymal transition)|go:""GO:0014004""(microglia differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031643""(positive regulation of myelination)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0035198""(miRNA binding)|go:""GO:0035886""(vascular associated smooth muscle cell differentiation)|go:""GO:0042552""(myelination)|go:""GO:0042759""(long-chain fatty acid biosynthetic process)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045649""(regulation of macrophage differentiation)|go:""GO:0045650""(negative regulation of macrophage differentiation)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0048710""(regulation of astrocyte differentiation)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0051028""(mRNA transport)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0160089""(""internal N(7)-methylguanine-containing RNA reader activity"")|go:""GO:0160091""(spliceosome-depend formation of circular RNA)|go:""GO:1905869""(negative regulation of 3'-UTR-mediated mRNA stabilization)|go:""GO:1990764""(myofibroblast contraction)|go:""GO:2000626""(negative regulation of miRNA catabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|interpro:IPR045071|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952|refseq:NP_001288014.1|refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:XP_011534561.1|efo:""Orphanet:251671""|ensembl:ENST00000275262.11|ensembl:ENSP00000275262.7|ensembl:ENST00000361195.6|ensembl:ENSP00000354867.2|ensembl:ENSP00000355094.3|ensembl:ENST00000361758.8|ensembl:ENSP00000354951.4|ensembl:ENST00000392127.6|ensembl:ENSP00000375973.2|ensembl:ENST00000424802.7|ensembl:ENSP00000408382.3|ensembl:ENST00000453779.6|ensembl:ENSP00000408775.2|panther:PTHR11208(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:0E39A6994061CBFA|rigid:1Vo3ByC/a8MYYiDTHfje6xu4f0g	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TAF3	uniprotkb:Q83A11	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491.5	intact:EBI-21286600	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286745|imex:IM-26899-693	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50841N|efo:""Orphanet:401800""|ensembl:ENSG00000114742.14(gene)|ensembl:ENST00000302313.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043588""(skin development)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:1902525""(regulation of protein monoubiquitination)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|interpro:IPR051246|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|refseq:NP_065890.1|panther:PTHR19862(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:1650B5BA36C4174F|rigid:MD+VMM+Xjaa41NKEwpbePvTPaWs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75436	uniprotkb:Q83A11	intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|uniprotkb:B2RDD3|uniprotkb:A8MZ56|ensembl:ENSP00000263559.6|ensembl:ENSP00000362480.1	intact:EBI-21286600	psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286739|imex:IM-26899-787	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N|ensembl:ENSG00000122958.15(gene)|ensembl:ENST00000263559.11(transcript)|ensembl:ENST00000373382.5(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030906""(retromer, cargo-selective complex)|go:""GO:0031982""(vesicle)|go:""GO:0032456""(endocytic recycling)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0097422""(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:7BLO|reactome:R-HSA-3238698|panther:PTHR12233(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/25	rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:2C22149EC51758B9|rigid:jFYYeg4AjlMzUhaMh8yGB1OcyU8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y3A6	uniprotkb:Q83A11	intact:EBI-7560959|uniprotkb:D3DT38|intact:MINT-3085589|uniprotkb:B2R703|uniprotkb:Q96AX8|uniprotkb:B1AKT4|ensembl:ENSP00000359305.3	intact:EBI-21286600	psi-mi:tmed5_human(display_long)|uniprotkb:TMED5(gene name)|psi-mi:TMED5(display_short)|uniprotkb:p24 family protein gamma-2(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:CGI-100(orf name)|uniprotkb:UNQ397/PRO733(orf name)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286715|imex:IM-26899-263	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001161302.1|refseq:NP_057124.3|ensembl:ENSG00000117500.13(gene)|ensembl:ENST00000370282.8(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090161""(Golgi ribbon formation)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q9Y3A6|reactome:R-HSA-3238698|panther:PTHR22811(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	comment:mint|comment:homomint	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/27	rogid:3XAcqSucHNP4F3ilaBFRMSQ1B8Q9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:DDFA8DCD208965EB|rigid:KH4TMMEnqBDrFOQygwRIVFlmg1Q	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O14818	uniprotkb:Q83A11	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|ensembl:ENSP00000359910.4|uniprotkb:Q5JXJ2	intact:EBI-21286600	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)|uniprotkb:Proteasome subunit alpha-4(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286685|imex:IM-26899-785	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002783.1|ensembl:ENSG00000101182.15(gene)|ensembl:ENST00000370873.9(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019773""(proteasome core complex, alpha-subunit complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR050115|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM3|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29363N|panther:PTHR11599(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/05	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:C9BAA286F50B9B99|rigid:g6fZeT05hdGYDRj+PbQWbsxvVp0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y320	uniprotkb:Q83A11	intact:EBI-6447886|uniprotkb:B7Z4R4|uniprotkb:Q8NBP9|uniprotkb:Q5J7Q7|uniprotkb:Q561W0|uniprotkb:Q53G73|uniprotkb:Q9H3L1|intact:EBI-7128726|intact:MINT-6945923|ensembl:ENSP00000278422.4	intact:EBI-21286600	psi-mi:tmx2_human(display_long)|uniprotkb:Cell proliferation-inducing gene 26 protein(gene name synonym)|uniprotkb:TXNDC14(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 14(gene name synonym)|uniprotkb:CGI-31(orf name)|uniprotkb:My009(orf name)|uniprotkb:PIG26(orf name)|uniprotkb:PSEC0045(orf name)|uniprotkb:UNQ237/PRO270(orf name)|uniprotkb:TMX2(gene name)|psi-mi:TMX2(display_short)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286721|imex:IM-26899-597	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137484.1|refseq:NP_057043.1|ensembl:ENSG00000213593.11(gene)|ensembl:ENST00000278422.9(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007420""(brain development)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037463|interpro:IPR039101|mint:Q9Y320|rcsb pdb:2DJ0|panther:PTHR15853(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:5YbR806GhogQ2yI3r9uo8i97MzY9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:D1097925BE7D5B31|rigid:A8yf6pgm50AAh4o4ZA118lqcwf4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TCU3	uniprotkb:Q83A11	intact:EBI-21285839|ensembl:ENSP00000297524.3|uniprotkb:Q05C37|uniprotkb:Q08AH9|uniprotkb:Q96N84	intact:EBI-21286600	psi-mi:s7a13_human(display_long)|uniprotkb:SLC7A13(gene name)|psi-mi:SLC7A13(display_short)|uniprotkb:AGT1(gene name synonym)|uniprotkb:XAT2(gene name synonym)|uniprotkb:Sodium-independent aspartate/glutamate transporter 1(gene name synonym)|uniprotkb:X-amino acid transporter 2(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286709|imex:IM-26899-397	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164893.9(gene)|ensembl:ENST00000297524.8(transcript)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015810""(aspartate transmembrane transport)|go:""GO:0015811""(L-cystine transport)|go:""GO:0015813""(L-glutamate transmembrane transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0046982""(protein heterodimerization activity)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR050598|mint:Q8TCU3|refseq:NP_620172.2|panther:PTHR11785(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:W8HPrBO1TnsueOONPohwDYH1z9c9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:49D4C09C6DF15489|rigid:KWSuenLRpAmDKTahEzkfP3DLtlY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9C040	uniprotkb:Q83A11	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|uniprotkb:D3DP09|ensembl:ENSP00000415812.2|ensembl:ENSP00000501586.1|ensembl:ENSP00000501612.1|ensembl:ENSP00000501652.1|ensembl:ENSP00000501662.1|ensembl:ENSP00000501792.1|ensembl:ENSP00000501822.1|ensembl:ENSP00000501951.1|ensembl:ENSP00000501994.1|ensembl:ENSP00000502089.1|ensembl:ENSP00000502114.1|ensembl:ENSP00000502159.1|ensembl:ENSP00000502273.1|ensembl:ENSP00000502348.1|ensembl:ENSP00000502356.1|ensembl:ENSP00000502519.1|ensembl:ENSP00000502543.1|ensembl:ENSP00000502676.1	intact:EBI-21286600	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286733|imex:IM-26899-267	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109654.16(gene)|ensembl:ENST00000437508.7(transcript)|ensembl:ENST00000674874.1(transcript)|ensembl:ENST00000674876.1(transcript)|ensembl:ENST00000674976.1(transcript)|ensembl:ENST00000675054.1(transcript)|ensembl:ENST00000675159.1(transcript)|ensembl:ENST00000675293.1(transcript)|ensembl:ENST00000675315.1(transcript)|ensembl:ENST00000675384.1(transcript)|ensembl:ENST00000675745.1(transcript)|ensembl:ENST00000675835.1(transcript)|ensembl:ENST00000676172.1(transcript)|ensembl:ENST00000676252.1(transcript)|ensembl:ENST00000676264.1(transcript)|ensembl:ENST00000676348.1(transcript)|ensembl:ENST00000676374.1(transcript)|ensembl:ENST00000676423.1(transcript)|ensembl:ENST00000676458.1(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030371""(translation repressor activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043523""(regulation of neuron apoptotic process)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|interpro:IPR050952|mint:Q9C040|rcsb pdb:7B2R|rcsb pdb:7B96|rcsb pdb:7QRV|rcsb pdb:7ZJ3|rcsb pdb:8A38|rcsb pdb:8AMS|reactome:R-HSA-877300|refseq:NP_001123539.1|refseq:NP_056086.2|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|efo:""Orphanet:397968""|panther:PTHR24104(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:F455264D32BA8558|rigid:D/z8uVXsWVRSm0BFoBjYQSdP5Xg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q86UE4	uniprotkb:Q83A11	intact:EBI-1046588|uniprotkb:Q8TCX3|uniprotkb:Q6PK07|ensembl:ENSP00000338235.3|uniprotkb:Q05DH2|uniprotkb:Q52QU9	intact:EBI-21286600	psi-mi:lyric_human(display_long)|uniprotkb:Lysine-rich CEACAM1 co-isolated protein(gene name synonym)|uniprotkb:3D3/LYRIC(gene name synonym)|uniprotkb:Metastasis adhesion protein(gene name synonym)|uniprotkb:Astrocyte elevated gene-1 protein(gene name synonym)|uniprotkb:MTDH(gene name)|psi-mi:MTDH(display_short)|uniprotkb:AEG1(gene name synonym)|uniprotkb:LYRIC(gene name synonym)|uniprotkb:Metadherin(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286679|imex:IM-26899-171	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000147649.10(gene)|ensembl:ENST00000336273.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046581""(intercellular canaliculus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR031402|interpro:IPR052305|mint:Q86UE4|rcsb pdb:4QMG|refseq:NP_848927.2|panther:PTHR23251(orthology-group)|ensembl:ENSP00000338235.3"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:daZhKhAOeoKGjfl0IXt1fZXn/I09606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:E7985A5770C921D8|rigid:9Gmxkz40QLtVM5FHtifxFjRwgRg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75970	uniprotkb:Q83A11	intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|uniprotkb:B2RTS3|ensembl:ENSP00000320006.7|intact:EBI-10961605	intact:EBI-21286600	psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286673|imex:IM-26899-261	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000107186.17(gene)|ensembl:ENST00000319217.12(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0030425""(dendrite)|go:""GO:0045177""(apical part of cell)|go:""GO:0120192""(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|interpro:IPR051342|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:NP_003820.2|refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:XP_016870742.1|efo:""Orphanet:269505""|panther:PTHR19964(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:8778A91FE79BE9B7|rigid:TazseQ3p2rSrJzT8JyTpcPzlu1A	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96EE3	uniprotkb:Q83A11	intact:EBI-922818|ensembl:ENSP00000262124.10|uniprotkb:Q8NFU6|uniprotkb:Q96MH3|uniprotkb:Q9C069|uniprotkb:A8K5B1	intact:EBI-21286600	psi-mi:seh1_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit SEH1(gene name synonym)|uniprotkb:SEH1L(gene name)|psi-mi:SEH1L(display_short)|uniprotkb:SEC13L(gene name synonym)|uniprotkb:SEH1(gene name synonym)|uniprotkb:SEC13-like protein(gene name synonym)|uniprotkb:GATOR2 complex protein SEH1(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286703|imex:IM-26899-691	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000085415.16(gene)|ensembl:ENST00000262124.15(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006999""(nuclear pore organization)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0015031""(protein transport)|go:""GO:0031080""(nuclear pore outer ring)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035859""(Seh1-associated complex)|reactome:R-HSA-3232142|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0051028""(mRNA transport)|go:""GO:0051301""(cell division)|go:""GO:0051315""(attachment of mitotic spindle microtubules to kinetochore)|go:""GO:0061700""(GATOR2 complex)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904263""(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001013455.1|refseq:NP_112493.2|interpro:IPR020472|interpro:IPR036322|interpro:IPR037363|mint:Q96EE3|rcsb pdb:5A9Q|rcsb pdb:7PEQ|rcsb pdb:7R5J|rcsb pdb:7R5K|rcsb pdb:7UHY|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-9705671|panther:PTHR11024(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:I/aUTa3zTawK6QwtkrUkO8B51W49606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:1C9CBA748EB6CE67|rigid:exO1mUKsun3zBaBe+OvecG8A3wU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8IX03	uniprotkb:Q83A11	intact:EBI-715828|uniprotkb:B4DK05|uniprotkb:O94946|uniprotkb:Q6MZX4|uniprotkb:Q6Y2F8|uniprotkb:Q7Z4G8|uniprotkb:Q8WVM4|uniprotkb:Q9BT29|ensembl:ENSP00000265293.4	intact:EBI-21286600	psi-mi:kibra_human(display_long)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Kidney and brain protein(gene name synonym)|uniprotkb:HBeAg-binding protein 3(gene name synonym)|uniprotkb:WWC1(gene name)|psi-mi:WWC1(display_short)|uniprotkb:KIAA0869(gene name synonym)|uniprotkb:KIBRA(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286751|imex:IM-26899-599	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001155134.1|refseq:NP_056053.1|refseq:NP_001155133.1|dip:DIP-35287N|ensembl:ENSG00000113645.15(gene)|ensembl:ENST00000265293.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0032386""(regulation of intracellular transport)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035329""(hippo signaling)|go:""GO:0035330""(regulation of hippo signaling)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0046621""(negative regulation of organ growth)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0099092""(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR036020|interpro:IPR037771|interpro:IPR051105|mint:Q8IX03|rcsb pdb:2Z0U|rcsb pdb:6FB4|rcsb pdb:6FD0|rcsb pdb:6FJC|rcsb pdb:6FJD|reactome:R-HSA-2028269|reactome:R-HSA-9013508|panther:PTHR14791(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:AGllK9/JguvRQEPw79FYfSgPjiU9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:D934E82C9BCEE29D|rigid:YyNNNNN7eRv/MQOaaJZAUwr7cms	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y2L5	uniprotkb:Q83A11	intact:EBI-2820056|uniprotkb:A0JP15|uniprotkb:B3KME5|uniprotkb:Q9H0L2|ensembl:ENSP00000283351.4	intact:EBI-21286600	psi-mi:tppc8_human(display_long)|uniprotkb:TRAPPC8(gene name)|psi-mi:TRAPPC8(display_short)|uniprotkb:KIAA1012(gene name synonym)|uniprotkb:Protein TRS85 homolog(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286727|imex:IM-26899-265	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055754.2|dip:DIP-48280N|ensembl:ENSG00000153339.15(gene)|ensembl:ENST00000283351.10(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0030008""(TRAPP complex)|go:""GO:0032964""(collagen biosynthetic process)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0099022""(vesicle tethering)|go:""GO:1990072""(TRAPPIII protein complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024420|mint:Q9Y2L5|reactome:R-HSA-8876198|panther:PTHR12975(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ofBTdvGAgN6zCUIydAmlZ0BpGsw9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:9E3B239A832E0DBB|rigid:f94hRJDUOAkhsI+9A5ZW4LNddhQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95104	uniprotkb:Q83A11	intact:EBI-2854897|uniprotkb:Q6P1M5|uniprotkb:Q8N3I8|uniprotkb:Q9ULP8|uniprotkb:Q0P5W8|uniprotkb:Q9UFM1|uniprotkb:C9JLZ0|ensembl:ENSP00000286835.7	intact:EBI-21286600	psi-mi:scaf4_human(display_long)|uniprotkb:SCAF4(gene name)|psi-mi:SCAF4(display_short)|uniprotkb:Splicing factor, arginine/serine-rich 15(gene name synonym)|uniprotkb:SFRS15(gene name synonym)|uniprotkb:KIAA1172(gene name synonym)|uniprotkb:CTD-binding SR-like protein RA4(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286697|imex:IM-26899-395	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034369|interpro:IPR035979|interpro:IPR051485|mint:O95104|rcsb pdb:6XKB|refseq:NP_001138916.1|refseq:NP_001138917.1|ensembl:ENSG00000156304.15(gene)|ensembl:ENST00000286835.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:1990269""(RNA polymerase II C-terminal domain phosphoserine binding)|go:""GO:2000805""(""negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled"")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|refseq:NP_065757.1|panther:PTHR23140(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:l++VfjjY/kfVHl+bhXTWsyyL4Zc9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:A5346C618ED054DA|rigid:DwSWvL/KJ1MFRBZtkXitDT9KW6k	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15072	uniprotkb:Q83A11	intact:EBI-11914212|uniprotkb:Q2TB94|ensembl:ENSP00000392095.1|ensembl:ENSP00000400391.1	intact:EBI-21286600	psi-mi:ozf_human(display_long)|uniprotkb:ZNF146(gene name)|psi-mi:ZNF146(display_short)|uniprotkb:OZF(gene name synonym)|uniprotkb:Only zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 146(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21286757|imex:IM-26899-695	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001093108.1|refseq:NP_001093109.1|refseq:NP_009076.2|refseq:XP_005259271.1|refseq:XP_016882733.1|refseq:XP_016882734.1|refseq:XP_016882735.1|refseq:XP_016882736.1|ensembl:ENSG00000167635.12(gene)|ensembl:ENST00000443387.3(transcript)|ensembl:ENST00000456324.5(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008201""(heparin binding)|go:""GO:0008270""(zinc ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q15072|panther:PTHR24377(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:N83ODeBIXcmLguIQ9eBIknUDsCs9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:1033095D6479C334|rigid:pd9CCl2P5Xh2ELn0sQUJSYoB9uA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P51955	uniprotkb:Q83D60	intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966.4	intact:EBI-21285556	psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288423|imex:IM-26899-833	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000117650.13(gene)|ensembl:ENST00000366999.9(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000922""(spindle pole)|go:""GO:0001824""(blastocyst development)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030496""(midbody)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046602""(regulation of mitotic centrosome separation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051299""(centrosome separation)|go:""GO:0051301""(cell division)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1903126""(negative regulation of centriole-centriole cohesion)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR051131|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|refseq:XP_005273204.1|efo:""Orphanet:791""|panther:PTHR43671(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:7iozc82+IF+sGyerzvp571Uc1RM9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:AF0D15E1301D76F5|rigid:4Kk5vKrDWEcJ2aNoyeSS8nh5N6s	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5JVL4	uniprotkb:Q83D60	intact:EBI-743105|uniprotkb:Q5XKM4|uniprotkb:Q6E1U7|uniprotkb:Q6E1U8|uniprotkb:Q8WUL2|uniprotkb:Q9NVW6|uniprotkb:B4DMU3|uniprotkb:F5GZD8|intact:EBI-11099619|ensembl:ENSP00000360107.4	intact:EBI-21285556	psi-mi:efhc1_human(display_long)|uniprotkb:EFHC1(gene name)|psi-mi:EFHC1(display_short)|uniprotkb:Myoclonin-1(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288399|imex:IM-26899-97	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1941""|efo:""Orphanet:307""|ensembl:ENSG00000096093.16(gene)|ensembl:ENST00000371068.11(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0000922""(spindle pole)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005813""(centrosome)|go:""GO:0005879""(axonemal microtubule)|go:""GO:0005930""(axoneme)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0036126""(sperm flagellum)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0051302""(regulation of cell division)|go:""GO:0060285""(cilium-dependent cell motility)|go:""GO:0072686""(mitotic spindle)|go:""GO:0160111""(axonemal A tubule inner sheath)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|mint:Q5JVL4|rcsb pdb:7UNG|rcsb pdb:8J07|refseq:NP_001165891.1|refseq:NP_060570.2|panther:PTHR12086(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:l5I5K4Lgihe08j5BuPBk4uDY+qk9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:2CC8B775116D783F|rigid:0I1OEHD17+5v0ClLdq5V/RPS5Q4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96ND8	uniprotkb:Q83DE4	intact:EBI-21285519|ensembl:ENSP00000291598.7|ensembl:ENSP00000388502.2|uniprotkb:O14850|uniprotkb:Q2NKK3	intact:EBI-21285423	psi-mi:zn583_human(display_long)|uniprotkb:ZNF583(gene name)|psi-mi:ZNF583(display_short)|uniprotkb:Zinc finger protein L3-5(gene name synonym)	psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288375|imex:IM-26899-733	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000198440.9(gene)|ensembl:ENST00000291598.11(transcript)|ensembl:ENST00000333201.13(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96ND8|reactome:R-HSA-212436|refseq:NP_001153332.1|refseq:NP_001153333.1|refseq:NP_689691.2|refseq:XP_011524819.1|refseq:XP_016881839.1|panther:PTHR24377(orthology-group)"	mint:Q83DE4|refseq:NP_819814.1|refseq:WP_010957806.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:K5sTOQhO2w/s5N/S+t9aFNGP/Ns9606	rogid:XVA7R483yYdpYkhCnAqOzU8u000227377	intact-crc:326B0B26148BBD0C|rigid:+yL4MNs50rgEnydBlD4VfoBYthw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5JRX3	uniprotkb:Q83D60	intact:EBI-2432778|uniprotkb:B4E0J8|uniprotkb:E7ES23|uniprotkb:B3KMJ6|uniprotkb:O95204|uniprotkb:Q2M2G6|uniprotkb:Q4VBR1|uniprotkb:Q5JRW7|uniprotkb:Q7L5Z7|uniprotkb:Q9BSI6|uniprotkb:Q9BVJ5|uniprotkb:Q9UPP8|uniprotkb:C9JSL2|ensembl:ENSP00000224949.4	intact:EBI-21285556	psi-mi:prep_human(display_long)|uniprotkb:PITRM1(gene name)|psi-mi:PITRM1(display_short)|uniprotkb:KIAA1104(gene name synonym)|uniprotkb:MP1(gene name synonym)|uniprotkb:Pitrilysin metalloproteinase 1(gene name synonym)|uniprotkb:PREP(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288429|imex:IM-26899-99	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229236.1|refseq:NP_001229238.1|refseq:NP_055704.2|ensembl:ENSG00000107959.17(gene)|ensembl:ENST00000224949.9(transcript)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006508""(proteolysis)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016485""(protein processing)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR013578(Peptidase M16C associated)|interpro:IPR055130|mint:Q5JRX3|rcsb pdb:4L3T|rcsb pdb:4NGE|rcsb pdb:4RPU|rcsb pdb:6XOS|rcsb pdb:6XOT|rcsb pdb:6XOU|rcsb pdb:6XOV|rcsb pdb:6XOW|reactome:R-HSA-1268020|dip:DIP-52900N|panther:PTHR43016(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:1kEY/XJB5fwgNRoM9u9ZGT+VrS09606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:23C5FDA1AD09F881|rigid:DFGF+X6QcG/CnhozoDIq70n0zhE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q68CP9	uniprotkb:Q83D60	intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044.6	intact:EBI-21285556	psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288381|imex:IM-26899-829	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000189079.18(gene)|ensembl:ENST00000334344.11(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006337""(nucleosome disassembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|interpro:IPR003150(DNA-binding RFX)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0042592""(homeostatic process)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0048568""(embryonic organ development)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|interpro:IPR052406|mint:Q68CP9|rcsb pdb:7VDV|rcsb pdb:7Y8R|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_001334768.1|refseq:NP_689854.2|dip:DIP-33391N|efo:""Orphanet:1465"""	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/17	rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:B9FC44BCC76D9CF5|rigid:+TsiYi8O1ve39fliPp/FgOP8wPs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q58WW2	uniprotkb:Q83D60	intact:EBI-2559044|ensembl:ENSP00000311949.6|uniprotkb:Q8TB19|uniprotkb:Q8IXH3|uniprotkb:A2A295|uniprotkb:Q7L8I0|uniprotkb:B4DNB8	intact:EBI-21285556	psi-mi:dcaf6_human(display_long)|uniprotkb:DCAF6(gene name)|psi-mi:DCAF6(display_short)|uniprotkb:IQWD1(gene name synonym)|uniprotkb:Nuclear receptor interaction protein(gene name synonym)|uniprotkb:IQ motif and WD repeat-containing protein 1(gene name synonym)|uniprotkb:Androgen receptor complex-associated protein(gene name synonym)|uniprotkb:MSTP055(orf name)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288387|imex:IM-26899-633	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143164.16(gene)|ensembl:ENST00000312263.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR045151|mint:Q58WW2|rcsb pdb:3I7O|reactome:R-HSA-8951664|refseq:NP_001017977.1|refseq:NP_001185885.1|refseq:NP_001185886.1|refseq:NP_060912.2|dip:DIP-44678N|panther:PTHR15574(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/25	rogid:1CtoPWPj6fdryvDlC46pXiUguDc9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:877EF99E4C0BCBC9|rigid:SL2YGhKlOaBwieGivUD22hIBeA4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NSE4	uniprotkb:Q83D60	intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889.2	intact:EBI-21285556	psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288417|imex:IM-26899-555	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:436174""|ensembl:ENSG00000067704.10(gene)|ensembl:ENST00000366922.3(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004822""(isoleucine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006418""(tRNA aminoacylation for protein translation)|go:""GO:0006428""(isoleucyl-tRNA aminoacylation)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|interpro:IPR050081|mint:Q9NSE4|reactome:R-HSA-379726|reactome:R-HSA-9837999|refseq:NP_060530.3|panther:PTHR42765(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:E188B710BD651370|rigid:JaivoSuemMz+vo3ANQhZZ/e27nM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UNP9	uniprotkb:Q83D60	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769.5	intact:EBI-21285556	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288435|imex:IM-26899-557	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006103.1|refseq:NP_001181936.1|ensembl:ENSG00000084072.17(gene)|ensembl:ENST00000324379.10(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006457""(protein folding)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0016018""(cyclosporin A binding)|go:""GO:0016607""(nuclear speck)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:7ZEV|rcsb pdb:7ZEW|rcsb pdb:7ZEX|rcsb pdb:7ZEY|rcsb pdb:7ZEZ|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:9FMD|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163|refseq:NP_982281.1|refseq:XP_016855540.1|dip:DIP-34757N"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/21	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:C8D85D53DE89FC25|rigid:Ys7GfTvJwmBH8iSN/2XhiHKXDjk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBW7	uniprotkb:Q83D60	intact:EBI-2797576|ensembl:ENSP00000372324.2|ensembl:ENSP00000372327.2|ensembl:ENSP00000479904.1|intact:EBI-25598824|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898	intact:EBI-21285556	psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288447|imex:IM-26899-835	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000121741.17(gene)|ensembl:ENST00000382871.3(transcript)|ensembl:ENST00000382874.6(transcript)|ensembl:ENST00000610343.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016605""(PML body)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|interpro:IPR051284|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|refseq:XP_005266577.1|refseq:XP_011533526.1|refseq:XP_016876218.1|efo:""Orphanet:528084""|panther:PTHR45736(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:C1EB165B206CEB04|rigid:V1C2fEBWAyD9nhn6UKIoHHd5YVU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NXN4	uniprotkb:Q83D60	intact:EBI-10316460|ensembl:ENSP00000358451.4|uniprotkb:Q96DZ0	intact:EBI-21285556	psi-mi:gdap2_human(display_long)|uniprotkb:GDAP2(gene name)|psi-mi:GDAP2(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288411|imex:IM-26899-831	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000196505.11(gene)|ensembl:ENST00000369443.10(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0032526""(response to retinoic acid)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR035793|interpro:IPR036865|interpro:IPR043472|mint:Q9NXN4|rcsb pdb:4UML|refseq:NP_001129061.1|refseq:NP_060156.1|panther:PTHR11106(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:2fjIQzKGImu2CwNw2ul5gti/28g9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:7D03DF9B4056EF6F|rigid:a89t1FSvlGWGh/UMdVF4fI3ASiI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NP50	uniprotkb:Q83D60	intact:EBI-741906|uniprotkb:Q9BSZ8|uniprotkb:D3DUV8|ensembl:ENSP00000337477.4|ensembl:ENSP00000393279.2|ensembl:ENSP00000479093.1|ensembl:ENSP00000488570.1	intact:EBI-21285556	psi-mi:shcaf_human(display_long)|uniprotkb:SINHCAF(gene name)|psi-mi:SINHCAF(display_short)|uniprotkb:C12orf14(gene name synonym)|uniprotkb:FAM60A(gene name synonym)|uniprotkb:Protein FAM60A(gene name synonym)|uniprotkb:Tera protein homolog(gene name synonym)|uniprotkb:L4(orf name)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288405|imex:IM-26899-539	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001129283.1|refseq:NP_001129284.1|refseq:NP_067061.1|refseq:XP_016875247.1|refseq:XP_016875248.1|refseq:XP_016875249.1|refseq:XP_016875250.1|refseq:XP_016875251.1|ensembl:ENSG00000139146.14(gene)|ensembl:ENSG00000276371.2(gene)|ensembl:ENST00000337682.9(transcript)|ensembl:ENST00000454658.6(transcript)|ensembl:ENST00000617411.2(transcript)|ensembl:ENST00000633702.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0005634""(nucleus)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0070822""(Sin3-type complex)|go:""GO:1902455""(negative regulation of stem cell population maintenance)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR026065|mint:Q9NP50|refseq:XP_011519105.1|panther:PTHR13422(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:LVESO8KQhobNYQduBQ/iAmNaNTM9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:16717D170B70665A|rigid:UJqXZov6x8YBXcn0B7qOGuDBNCk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P49802	uniprotkb:Q83D60	intact:EBI-1754797|uniprotkb:Q8TD66|uniprotkb:Q8TD67|uniprotkb:Q9UNU7|uniprotkb:Q9Y6B9|uniprotkb:Q5T3H4|uniprotkb:Q8WW09|ensembl:ENSP00000404399.2	intact:EBI-21285556	psi-mi:rgs7_human(display_long)|uniprotkb:RGS7(gene name)|psi-mi:RGS7(display_short)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288441|imex:IM-26899-205	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269702.1|refseq:NP_001269704.1|refseq:NP_001269707.1|refseq:NP_002915.3|ensembl:ENSG00000182901.18(gene)|ensembl:ENST00000440928.6(transcript)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0031681""(G-protein beta-subunit binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0043005""(neuron projection)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045471""(response to ethanol)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:1901381""(positive regulation of potassium ion transmembrane transport)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036284|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|interpro:IPR040759|interpro:IPR044926|interpro:IPR047016|interpro:IPR047017|mint:P49802|rcsb pdb:2A72|rcsb pdb:2D9J|rcsb pdb:7EWP|rcsb pdb:7EWR|rcsb pdb:7SHF|reactome:R-HSA-418594|reactome:R-HSA-6814122|refseq:XP_005273275.1|dip:DIP-40869N|panther:PTHR45746(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:epeNPVu00d27S9hlaKto1/bKwhI9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:A14437F3654A9C97|rigid:HBFX7OQnp4clvuCTuIcXYrvP/tA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O00399	uniprotkb:Q83D60	intact:EBI-2559415|ensembl:ENSP00000221114.3|uniprotkb:B2RAC1	intact:EBI-21285556	psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym)	psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288393|imex:IM-26899-95	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000104671.8(gene)|ensembl:ENST00000221114.8(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0070840""(dynein complex binding)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|refseq:NP_006562.1|panther:PTHR13072(orthology-group)"	mint:Q83D60|refseq:NP_819899.1|refseq:WP_010957865.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/28	rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606	rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377	intact-crc:B1ACB69D6FAEBD98|rigid:EfaYGRCh3l3nsqovsatet4tcr0M	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8NCW5	uniprotkb:Q83B01	intact:EBI-2564619|uniprotkb:B4DGY3|uniprotkb:Q496C6|uniprotkb:Q5T3I2|ensembl:ENSP00000357218.3|ensembl:ENSP00000505349.1|ensembl:ENSP00000505899.1|ensembl:ENSP00000505913.1|ensembl:ENSP00000506192.1|ensembl:ENSP00000506275.1	intact:EBI-21286307	"psi-mi:nnre_human(display_long)|uniprotkb:NAXE(gene name)|psi-mi:NAXE(display_short)|uniprotkb:AIBP(gene name synonym)|uniprotkb:APOA1BP(gene name synonym)|uniprotkb:Apolipoprotein A-I-binding protein(gene name synonym)|uniprotkb:""NAD(P)HX epimerase""(gene name synonym)|uniprotkb:YJEFN1(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 1(gene name synonym)"	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288459|imex:IM-26899-735	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000163382.13(gene)|ensembl:ENST00000368235.8(transcript)|ensembl:ENST00000679702.1(transcript)|ensembl:ENST00000680004.1(transcript)|ensembl:ENST00000680269.1(transcript)|ensembl:ENST00000681054.1(transcript)|ensembl:ENST00000681523.1(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006869""(lipid transport)|go:""GO:0010874""(regulation of cholesterol efflux)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0031580""(membrane raft distribution)|go:""GO:0042802""(identical protein binding)|go:""GO:0044297""(cell body)|go:""GO:0046496""(nicotinamide nucleotide metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0052856""(""NAD(P)HX epimerase activity"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0110051""(metabolite repair)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR032976|interpro:IPR036652|mint:Q8NCW5|reactome:R-HSA-197264|refseq:NP_658985.2|efo:""Orphanet:555407""|panther:PTHR13232(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:Sbye6Tfjl+zVbAgoFH2zdfqe3709606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:C3E26847819400ED|rigid:7l1sDHaF59xQ8pdpzVoyZhcM6F8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q0VDF9	uniprotkb:Q83B01	intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623.3	intact:EBI-21286307	psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym)|uniprotkb:Heat shock protein family A member 14(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288477|imex:IM-26899-435	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057383.2|ensembl:ENSG00000187522.16(gene)|ensembl:ENST00000378372.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N|panther:PTHR19375(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/05	rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:AFECD8EE0AD1B688|rigid:FWVbS9yMvt6dQY1NN+DxLig0E6Q	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBP4	uniprotkb:Q83B01	intact:EBI-954409|uniprotkb:Q9ULB7|uniprotkb:A8K1I2|uniprotkb:D3DQW1|ensembl:ENSP00000314910.4|ensembl:ENSP00000379762.2|ensembl:ENSP00000506835.1	intact:EBI-21286307	psi-mi:dkk3_human(display_long)|uniprotkb:REIC(gene name synonym)|uniprotkb:UNQ258/PRO295(orf name)|uniprotkb:DKK3(gene name)|psi-mi:DKK3(display_short)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288471|imex:IM-26899-115	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001018067.1|refseq:NP_037385.2|refseq:NP_056965.3|refseq:XP_006718241.1|refseq:NP_001317149.1|ensembl:ENSG00000050165.19(gene)|ensembl:ENST00000326932.8(transcript)|ensembl:ENST00000396505.7(transcript)|ensembl:ENST00000683431.1(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030325""(adrenal gland development)|go:""GO:0032348""(negative regulation of aldosterone biosynthetic process)|go:""GO:0039706""(co-receptor binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048019""(receptor antagonist activity)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1902613""(negative regulation of anti-Mullerian hormone signaling pathway)|go:""GO:2000065""(negative regulation of cortisol biosynthetic process)|interpro:IPR006796(Dickkopf, N-terminal cysteine-rich)|interpro:IPR039863|interpro:IPR047300|interpro:IPR047301|mint:Q9UBP4|panther:PTHR12113(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:pnbEZP5fAWw3Qxg1gB1sjP0Oyeo9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:4B0CE4C553EED09C|rigid:iTJLNNhnsXsWJWxA0SJo2IMGk30	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UIJ7	uniprotkb:Q83B01	intact:EBI-3916527|ensembl:ENSP00000371230.3|uniprotkb:Q5VYW6|uniprotkb:Q9NPB4|uniprotkb:Q9H576|uniprotkb:D3DRI1|uniprotkb:Q9HC01|uniprotkb:B4DP58|uniprotkb:E7ET30	intact:EBI-21286307	psi-mi:kad3_human(display_long)|uniprotkb:AK3(gene name)|psi-mi:AK3(display_short)|uniprotkb:AK3L1(gene name synonym)|uniprotkb:AK6(gene name synonym)|uniprotkb:AKL3L(gene name synonym)|uniprotkb:Adenylate kinase 3(gene name synonym)|uniprotkb:Adenylate kinase 3 alpha-like 1(gene name synonym)|uniprotkb:Adenylate kinase isozyme 3(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288453|imex:IM-26899-313	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000147853.17(gene)|ensembl:ENST00000381809.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006172""(ADP biosynthetic process)|go:""GO:0007596""(blood coagulation)|go:""GO:0009142""(nucleoside triphosphate biosynthetic process)|go:""GO:0016874""(ligase activity)|go:""GO:0046033""(AMP metabolic process)|go:""GO:0046039""(GTP metabolic process)|go:""GO:0046041""(ITP metabolic process)|go:""GO:0046051""(UTP metabolic process)|go:""GO:0046899""(nucleoside triphosphate adenylate kinase activity)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028586|interpro:IPR033690|interpro:IPR036193|mint:Q9UIJ7|rcsb pdb:1ZD8|rcsb pdb:6ZJB|rcsb pdb:6ZJD|rcsb pdb:6ZJE|reactome:R-HSA-983231|refseq:NP_001186781.1|refseq:NP_001186782.1|refseq:NP_001186784.1|refseq:NP_001186785.1|refseq:NP_057366.2|panther:PTHR23359(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:NDt9xiBjW8L9uXYnyZhVYpVybfA9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:9334AD2DBCC3ABB7|rigid:kSYNWJcKrJbUfiz+ajQ6iyKLmVM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P53779	uniprotkb:Q83B01	intact:EBI-713543|uniprotkb:A6NFS3|uniprotkb:Q15707|uniprotkb:Q49AP1|uniprotkb:A6NG28|uniprotkb:B3KQ94|ensembl:ENSP00000424154.3|ensembl:ENSP00000492204.1|ensembl:ENSP00000492292.1|ensembl:ENSP00000492903.1|ensembl:ENSP00000493013.1|ensembl:ENSP00000493045.1|ensembl:ENSP00000493072.1|ensembl:ENSP00000493275.1|ensembl:ENSP00000493290.1|ensembl:ENSP00000493363.1|ensembl:ENSP00000493375.1|ensembl:ENSP00000493408.1|ensembl:ENSP00000493435.1|ensembl:ENSP00000493450.1	intact:EBI-21286307	psi-mi:mk10_human(display_long)|uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)|uniprotkb:MAP kinase p49 3F12(gene name synonym)|uniprotkb:MAPK10(gene name)|psi-mi:MAPK10(display_short)|uniprotkb:JNK3(gene name synonym)|uniprotkb:JNK3A(gene name synonym)|uniprotkb:PRKM10(gene name synonym)|uniprotkb:Stress-activated protein kinase 1b(gene name synonym)|uniprotkb:SAPK1B(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288483|imex:IM-26899-315	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2382""|ensembl:ENSG00000109339.24(gene)|ensembl:ENST00000515400.3(transcript)|ensembl:ENST00000515650.2(transcript)|ensembl:ENST00000638313.1(transcript)|ensembl:ENST00000641051.1(transcript)|ensembl:ENST00000641066.1(transcript)|ensembl:ENST00000641157.1(transcript)|ensembl:ENST00000641207.1(transcript)|ensembl:ENST00000641341.1(transcript)|ensembl:ENST00000641462.2(transcript)|ensembl:ENST00000641647.1(transcript)|ensembl:ENST00000641823.1(transcript)|ensembl:ENST00000641902.1(transcript)|ensembl:ENST00000641952.1(transcript)|ensembl:ENST00000641983.1(transcript)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004708""(MAP kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0009416""(response to light stimulus)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0048511""(rhythmic process)|go:""GO:0090398""(cellular senescence)|go:""GO:0106310""(protein serine kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR050117|mint:P53779|rcsb pdb:1JNK|rcsb pdb:1PMN|rcsb pdb:1PMU|rcsb pdb:1PMV|rcsb pdb:2B1P|rcsb pdb:2EXC|rcsb pdb:2O0U|rcsb pdb:2O2U|rcsb pdb:2OK1|rcsb pdb:2P33|rcsb pdb:2R9S|rcsb pdb:2WAJ|rcsb pdb:2ZDT|rcsb pdb:2ZDU|rcsb pdb:3CGF|rcsb pdb:3CGO|rcsb pdb:3DA6|rcsb pdb:3FI2|rcsb pdb:3FI3|rcsb pdb:3FV8|rcsb pdb:3G90|rcsb pdb:3G9L|rcsb pdb:3G9N|rcsb pdb:3KVX|rcsb pdb:3OXI|rcsb pdb:3OY1|rcsb pdb:3PTG|rcsb pdb:3RTP|rcsb pdb:3TTI|rcsb pdb:3TTJ|rcsb pdb:3V6R|rcsb pdb:3V6S|rcsb pdb:4H36|rcsb pdb:4H39|rcsb pdb:4H3B|rcsb pdb:4KKE|rcsb pdb:4KKG|rcsb pdb:4KKH|rcsb pdb:4U79|rcsb pdb:4W4V|rcsb pdb:4W4W|rcsb pdb:4W4X|rcsb pdb:4W4Y|rcsb pdb:4WHZ|rcsb pdb:4Y46|rcsb pdb:4X21|rcsb pdb:4Y5H|rcsb pdb:4Z9L|rcsb pdb:6EKD|rcsb pdb:6EMH|rcsb pdb:6EQ9|rcsb pdb:7KSI|rcsb pdb:7KSJ|rcsb pdb:7KSK|rcsb pdb:7ORE|rcsb pdb:7ORF|rcsb pdb:7S1N|rcsb pdb:7YL1|rcsb pdb:8BZP|rcsb pdb:8ENJ|rcsb pdb:8WGF|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-450341|refseq:NP_001304996.1|refseq:NP_001304997.1|refseq:NP_001304998.1|refseq:NP_002744.1|refseq:NP_620446.1|refseq:NP_620448.1|refseq:XP_005263186.1|refseq:XP_005263187.1|refseq:XP_005263192.1|refseq:XP_006714331.1|refseq:XP_011530419.1|refseq:XP_011530420.1|refseq:XP_011530422.1|refseq:XP_011530423.1|refseq:XP_016863908.1|refseq:XP_016863909.1|refseq:XP_016863910.1|refseq:XP_016863912.1|refseq:XP_016863913.1|refseq:XP_016863914.1|refseq:XP_016863915.1|refseq:XP_016863918.1|refseq:XP_016863919.1|refseq:XP_016863920.1|refseq:XP_016863921.1|dip:DIP-1015N|panther:PTHR24055(orthology-group)|ensembl:ENST00000395157.9|ensembl:ENSP00000378586.4|ensembl:ENST00000395166.6|ensembl:ENSP00000378595.1|ensembl:ENSP00000424154.3|ensembl:ENSP00000492204.1|ensembl:ENST00000638225.1|ensembl:ENSP00000491866.1|ensembl:ENSP00000492292.1|ensembl:ENST00000639175.1|ensembl:ENSP00000491160.1|ensembl:ENST00000639234.1|ensembl:ENSP00000491306.1|ensembl:ENST00000639242.1|ensembl:ENSP00000491089.1|ensembl:ENST00000640858.1|ensembl:ENSP00000491122.1|ensembl:ENST00000640970.1|ensembl:ENSP00000492231.1|ensembl:ENST00000641050.1|ensembl:ENSP00000493270.1|ensembl:ENSP00000493275.1|ensembl:ENSP00000493072.1|ensembl:ENST00000641110.1|ensembl:ENSP00000493163.1|ensembl:ENSP00000493363.1|ensembl:ENST00000641170.1|ensembl:ENSP00000493237.1|ensembl:ENSP00000493450.1|ensembl:ENST00000641274.1|ensembl:ENSP00000492929.1|ensembl:ENST00000641283.1|ensembl:ENSP00000493444.1|ensembl:ENST00000641287.1|ensembl:ENSP00000493100.1|ensembl:ENST00000641297.1|ensembl:ENSP00000493092.1|ensembl:ENSP00000493290.1|ensembl:ENST00000641391.1|ensembl:ENSP00000493008.1|ensembl:ENST00000641410.1|ensembl:ENSP00000493208.1|ensembl:ENSP00000493435.1|ensembl:ENSP00000493375.1|ensembl:ENST00000641657.1|ensembl:ENSP00000493105.1|ensembl:ENST00000641724.1|ensembl:ENSP00000493038.1|ensembl:ENST00000641737.1|ensembl:ENSP00000493177.1|ensembl:ENST00000641803.1|ensembl:ENSP00000493049.1|ensembl:ENSP00000493408.1|ensembl:ENST00000641862.1|ensembl:ENSP00000493396.1|ensembl:ENSP00000492903.1|ensembl:ENST00000641911.1|ensembl:ENSP00000493374.1|ensembl:ENST00000641943.1|ensembl:ENSP00000492941.1|ensembl:ENSP00000493013.1|ensembl:ENSP00000493045.1|ensembl:ENST00000642009.1|ensembl:ENSP00000493168.1|ensembl:ENST00000642015.1|ensembl:ENSP00000493040.1|ensembl:ENST00000642038.1|ensembl:ENSP00000492942.1|ensembl:ENST00000642103.1|ensembl:ENSP00000493001.1"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/03/20	rogid:dzYzsLACbyCktFnxNeBXEf02BdA9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:9515A95227DC722A|rigid:+NdfihVfGv2hJAD3SwTEV6aPNV4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43396	uniprotkb:Q83B01	intact:EBI-1048857|ensembl:ENSP00000217515.5|ensembl:ENSP00000464918.1	intact:EBI-21286307	psi-mi:txnl1_human(display_long)|uniprotkb:32 kDa thioredoxin-related protein(gene name synonym)|uniprotkb:TXNL1(gene name)|psi-mi:TXNL1(display_short)|uniprotkb:TRP32(gene name synonym)|uniprotkb:TXL(gene name synonym)|uniprotkb:TXNL(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288489|imex:IM-26899-837	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004777.1|ensembl:ENSG00000091164.13(gene)|ensembl:ENST00000217515.11(transcript)|ensembl:ENST00000590954.5(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010400(Protein of unknown function DUF1000)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR037047|mint:O43396|rcsb pdb:1GH2|rcsb pdb:1WWY|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:XP_016881582.1|panther:PTHR46115(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:v3qpLTWgZZ1f4Tz/ixVYlSPv7Ro9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:7D78E57DD994D646|rigid:HDvvd31/ErzVuSKv1Gx+8dHd3L4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14562	uniprotkb:Q83B01	intact:EBI-2511477|ensembl:ENSP00000262415.2|ensembl:ENSP00000496923.1	intact:EBI-21286307	psi-mi:dhx8_human(display_long)|uniprotkb:DHX8(gene name)|psi-mi:DHX8(display_short)|uniprotkb:DDX8(gene name synonym)|uniprotkb:DEAH box protein 8(gene name synonym)|uniprotkb:RNA helicase HRH1(gene name synonym)	psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288465|imex:IM-26899-207	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000067596.12(gene)|ensembl:ENST00000262415.8(transcript)|ensembl:ENST00000650571.1(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0008380""(RNA splicing)|go:""GO:0016604""(nuclear body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR003029(S1, RNA binding)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044762|interpro:IPR048333|interpro:IPR049588|interpro:IPR049621|mint:Q14562|rcsb pdb:2EQS|rcsb pdb:3I4U|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:6HYS|rcsb pdb:6HYT|rcsb pdb:6HYU|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:9FMD|reactome:R-HSA-72163|refseq:NP_004932.1|refseq:NP_001289552.1|panther:PTHR18934(orthology-group)"	mint:Q83B01|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:ZUmh+KApFNV5NKCq6dizDgnw/Dw9606	rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377	intact-crc:42D48FFA184B5F4D|rigid:9YBxwe3yUftBuztZR3DQVvIQPMI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75970	uniprotkb:Q83A11	intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|uniprotkb:B2RTS3|ensembl:ENSP00000320006.7|intact:EBI-10961605	intact:EBI-21286600	psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288519|imex:IM-26899-841	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000107186.17(gene)|ensembl:ENST00000319217.12(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0030425""(dendrite)|go:""GO:0045177""(apical part of cell)|go:""GO:0120192""(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|interpro:IPR051342|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:NP_003820.2|refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:XP_016870742.1|efo:""Orphanet:269505""|panther:PTHR19964(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:4B3D6A76D02B983D|rigid:TazseQ3p2rSrJzT8JyTpcPzlu1A	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q0VDF9	uniprotkb:Q83A11	intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623.3	intact:EBI-21286600	psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym)|uniprotkb:Heat shock protein family A member 14(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288513|imex:IM-26899-839	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057383.2|ensembl:ENSG00000187522.16(gene)|ensembl:ENST00000378372.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N|panther:PTHR19375(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/05	rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:728A3C8453D2FB30|rigid:0kzJz0Zm2yCo6PT+HLT9rNx32YM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75436	uniprotkb:Q83A11	intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|uniprotkb:B2RDD3|uniprotkb:A8MZ56|ensembl:ENSP00000263559.6|ensembl:ENSP00000362480.1	intact:EBI-21286600	psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288531|imex:IM-26899-737	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N|ensembl:ENSG00000122958.15(gene)|ensembl:ENST00000263559.11(transcript)|ensembl:ENST00000373382.5(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030906""(retromer, cargo-selective complex)|go:""GO:0031982""(vesicle)|go:""GO:0032456""(endocytic recycling)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0097422""(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:7BLO|reactome:R-HSA-3238698|panther:PTHR12233(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/02/25	rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:A3127FB3B64CBC06|rigid:jFYYeg4AjlMzUhaMh8yGB1OcyU8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TAF3	uniprotkb:Q83A33	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491.5	intact:EBI-21286457	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288507|imex:IM-26899-637	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50841N|efo:""Orphanet:401800""|ensembl:ENSG00000114742.14(gene)|ensembl:ENST00000302313.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043588""(skin development)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:1902525""(regulation of protein monoubiquitination)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|interpro:IPR051246|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|refseq:NP_065890.1|panther:PTHR19862(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:17ADF0E94ED0BDDB|rigid:x8n86EoLhVAxPifCn3xVbYXUAF4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O00399	uniprotkb:Q83A33	intact:EBI-2559415|ensembl:ENSP00000221114.3|uniprotkb:B2RAC1	intact:EBI-21286457	psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288495|imex:IM-26899-635	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000104671.8(gene)|ensembl:ENST00000221114.8(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0070840""(dynein complex binding)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|refseq:NP_006562.1|panther:PTHR13072(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2025/01/28	rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:6EB4A8E215C5BC30|rigid:sqWORM+nQHm1D/7ovttVOd/5+x0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H0F5	uniprotkb:Q83A33	intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748|ensembl:ENSP00000259605.6	intact:EBI-21286457	psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym)	psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288501|imex:IM-26899-437	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1|ensembl:ENSG00000137075.18(gene)|ensembl:ENST00000259605.11(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008584""(male gonad development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0036126""(sperm flagellum)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:7OJX|panther:PTHR46171(orthology-group)"	"mint:Q83A33|go:""GO:0005524""(ATP binding)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|panther:PTHR13504(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606	rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377	intact-crc:EABC13D81A8E16CC|rigid:BJicUcaEQyoCjLBfcjejDFmBLnk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y320	uniprotkb:Q83A11	intact:EBI-6447886|uniprotkb:B7Z4R4|uniprotkb:Q8NBP9|uniprotkb:Q5J7Q7|uniprotkb:Q561W0|uniprotkb:Q53G73|uniprotkb:Q9H3L1|intact:EBI-7128726|intact:MINT-6945923|ensembl:ENSP00000278422.4	intact:EBI-21286600	psi-mi:tmx2_human(display_long)|uniprotkb:Cell proliferation-inducing gene 26 protein(gene name synonym)|uniprotkb:TXNDC14(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 14(gene name synonym)|uniprotkb:CGI-31(orf name)|uniprotkb:My009(orf name)|uniprotkb:PIG26(orf name)|uniprotkb:PSEC0045(orf name)|uniprotkb:UNQ237/PRO270(orf name)|uniprotkb:TMX2(gene name)|psi-mi:TMX2(display_short)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288525|imex:IM-26899-209	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137484.1|refseq:NP_057043.1|ensembl:ENSG00000213593.11(gene)|ensembl:ENST00000278422.9(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007420""(brain development)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037463|interpro:IPR039101|mint:Q9Y320|rcsb pdb:2DJ0|panther:PTHR15853(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:5YbR806GhogQ2yI3r9uo8i97MzY9606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:037608CA0D9D76E1|rigid:A8yf6pgm50AAh4o4ZA118lqcwf4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TAF3	uniprotkb:Q83A11	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491.5	intact:EBI-21286600	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2016)	imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-21288537|imex:IM-26899-317	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50841N|efo:""Orphanet:401800""|ensembl:ENSG00000114742.14(gene)|ensembl:ENST00000302313.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043588""(skin development)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:1902525""(regulation of protein monoubiquitination)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|interpro:IPR051246|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|refseq:NP_065890.1|panther:PTHR19862(orthology-group)"	mint:Q83A11|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/07/06	2024/11/14	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377	intact-crc:DFB0CBC286141A4F|rigid:MD+VMM+Xjaa41NKEwpbePvTPaWs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UII2	uniprotkb:P69968	intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203.5|ensembl:ENSP00000494248.1	intact:EBI-20817299|uniprotkb:P16161|uniprotkb:Q663K2	"psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:""Inhibitor of F(1)F(o)-ATPase""(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short)"	psi-mi:tyea_yerpe(display_long)|uniprotkb:YPCD1.38c(locus name)|uniprotkb:y5040(locus name)|uniprotkb:y0043(locus name)|uniprotkb:YP_pCD45(locus name)|uniprotkb:tyeA(gene name)|psi-mi:tyeA(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817353|imex:IM-26497-692	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770.18(gene)|ensembl:ENSG00000285390.2(gene)|ensembl:ENST00000335514.10(transcript)|ensembl:ENST00000647074.2(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0009986""(cell surface)|go:""GO:0019899""(enzyme binding)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042030""(ATPase inhibitor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043532""(angiostatin binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051346""(negative regulation of hydrolase activity)|go:""GO:0051882""(mitochondrial depolarization)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0140260""(mitochondrial proton-transporting ATP synthase complex binding)|go:""GO:1901030""(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1903052""(positive regulation of proteolysis involved in protein catabolic process)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|go:""GO:1903578""(regulation of ATP metabolic process)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1905707""(negative regulation of mitochondrial ATP synthesis coupled proton transport)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|rcsb pdb:8H9E|rcsb pdb:8H9L|rcsb pdb:8H9S|rcsb pdb:8H9U|rcsb pdb:8KI3|panther:PTHR23407(orthology-group)"	mint:P69968|refseq:NP_395172.1|refseq:NP_857744.1|refseq:NP_857939.1|refseq:WP_002212965.1|interpro:IPR015144(TyeA)|interpro:IPR013351(Type III secretion system effector delivery regulator TyeA)|interpro:IPR038347|rcsb pdb:1XL3	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606	rogid:zI9wEJBIrVcC8DxDaY7ODlj1bH8632	intact-crc:C77BEAA7E62812B5|rigid:aiQJQmj+lYLYrOh8vzG2FXDBHCM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43707	uniprotkb:P69968	intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|uniprotkb:A4K467|ensembl:ENSP00000252699.2|ensembl:ENSP00000489220.1	intact:EBI-20817299|uniprotkb:P16161|uniprotkb:Q663K2	psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)	psi-mi:tyea_yerpe(display_long)|uniprotkb:YPCD1.38c(locus name)|uniprotkb:y5040(locus name)|uniprotkb:y0043(locus name)|uniprotkb:YP_pCD45(locus name)|uniprotkb:tyeA(gene name)|psi-mi:tyeA(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817323|imex:IM-26497-446	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:656""|ensembl:ENSG00000130402.14(gene)|ensembl:ENSG00000282844.2(gene)|ensembl:ENST00000252699.7(transcript)|ensembl:ENST00000634960.2(transcript)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001725""(stress fiber)|go:""GO:0001882""(nucleoside binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030050""(vesicle transport along actin filament)|go:""GO:0030054""(cell junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031143""(pseudopodium)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032417""(""positive regulation of sodium:proton antiporter activity"")|go:""GO:0032991""(protein-containing complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0042995""(cell projection)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051015""(actin filament binding)|go:""GO:0055001""(muscle cell development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|go:""GO:1900025""(negative regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|refseq:NP_004915.2|dip:DIP-33179N|panther:PTHR11915(orthology-group)"	mint:P69968|refseq:NP_395172.1|refseq:NP_857744.1|refseq:NP_857939.1|refseq:WP_002212965.1|interpro:IPR015144(TyeA)|interpro:IPR013351(Type III secretion system effector delivery regulator TyeA)|interpro:IPR038347|rcsb pdb:1XL3	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/28	rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606	rogid:zI9wEJBIrVcC8DxDaY7ODlj1bH8632	intact-crc:230A8AD23B55F608|rigid:2fnOb0+fZYumuG8NP/d/q7/PWaU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NZU5	uniprotkb:P69968	intact:EBI-5774016|ensembl:ENSP00000157600.3|uniprotkb:B4DG80	intact:EBI-20817299|uniprotkb:P16161|uniprotkb:Q663K2	psi-mi:lmcd1_human(display_long)|uniprotkb:LMCD1(gene name)|psi-mi:LMCD1(display_short)|uniprotkb:Dyxin(gene name synonym)	psi-mi:tyea_yerpe(display_long)|uniprotkb:YPCD1.38c(locus name)|uniprotkb:y5040(locus name)|uniprotkb:y0043(locus name)|uniprotkb:YP_pCD45(locus name)|uniprotkb:tyeA(gene name)|psi-mi:tyeA(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817335|imex:IM-26497-448	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"reactome:R-HSA-5683826|ensembl:ENSG00000071282.12(gene)|ensembl:ENST00000157600.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010611""(regulation of cardiac muscle hypertrophy)|go:""GO:0070886""(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR033724|interpro:IPR047120|mint:Q9NZU5|refseq:NP_055398.1|refseq:NP_001265162.1|refseq:NP_001265163.1|refseq:NP_001265164.1|panther:PTHR24211(orthology-group)"	mint:P69968|refseq:NP_395172.1|refseq:NP_857744.1|refseq:NP_857939.1|refseq:WP_002212965.1|interpro:IPR015144(TyeA)|interpro:IPR013351(Type III secretion system effector delivery regulator TyeA)|interpro:IPR038347|rcsb pdb:1XL3	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:m4j8sHWGlkjQimelP5ffZ31Lyeo9606	rogid:zI9wEJBIrVcC8DxDaY7ODlj1bH8632	intact-crc:B42885232313CDE3|rigid:UjmnTQ0qvaJ8hm6cB/lbpeUuHeM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43294	uniprotkb:P68640	intact:EBI-1051449|uniprotkb:Q9BPW3|uniprotkb:Q9Y2V5|uniprotkb:B2R8D5|ensembl:ENSP00000378332.3	intact:EBI-20817365|uniprotkb:P16160	psi-mi:tgfi1_human(display_long)|uniprotkb:TGFB1I1(gene name)|psi-mi:TGFB1I1(display_short)|uniprotkb:ARA55(gene name synonym)|uniprotkb:Hydrogen peroxide-inducible clone 5 protein(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 55 kDa(gene name synonym)|uniprotkb:Androgen receptor coactivator 55 kDa protein(gene name synonym)	psi-mi:yopn_yerpe(display_long)|uniprotkb:yopN(gene name)|psi-mi:yopN(display_short)|uniprotkb:lcrE(gene name synonym)|uniprotkb:YPCD1.39c(locus name)|uniprotkb:y5039(locus name)|uniprotkb:y0042(locus name)|uniprotkb:YP_pCD44(locus name)|uniprotkb:LcrE(gene name synonym)|uniprotkb:Yop4b(gene name synonym)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817396|imex:IM-26497-588	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035919.1|refseq:NP_001158191.1|refseq:NP_057011.2|dip:DIP-5931N|ensembl:ENSG00000140682.19(gene)|ensembl:ENST00000394863.8(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0016363""(nuclear matrix)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045165""(cell fate commitment)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048495""(Roundabout binding)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0070411""(I-SMAD binding)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|interpro:IPR047075|mint:O43294|panther:PTHR24216(orthology-group)"	"mint:P68640|refseq:NP_857743.1|refseq:NP_857938.1|refseq:NP_395173.1|refseq:WP_002212958.1|interpro:IPR010812(Hypersensitivity response secretion HrpJ)|interpro:IPR013401(Type III secretion regulator, YopN/LcrE/InvE/MxiC)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0050709""(negative regulation of protein secretion)|rcsb pdb:1XKP|rcsb pdb:1XL3"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:ekkGbwdFenBhBn0HzJjd4Szi61U9606	rogid:MKix/cQFqtaeWtEMcnieRrRgypM632	intact-crc:ADBF578CE1055935|rigid:c6M3wfDANhej5/imXjBf3xa3eUI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05783	uniprotkb:P68640	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	intact:EBI-20817365|uniprotkb:P16160	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:yopn_yerpe(display_long)|uniprotkb:yopN(gene name)|psi-mi:yopN(display_short)|uniprotkb:lcrE(gene name synonym)|uniprotkb:YPCD1.39c(locus name)|uniprotkb:y5039(locus name)|uniprotkb:y0042(locus name)|uniprotkb:YP_pCD44(locus name)|uniprotkb:LcrE(gene name synonym)|uniprotkb:Yop4b(gene name synonym)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817402|imex:IM-26497-726	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	"mint:P68640|refseq:NP_857743.1|refseq:NP_857938.1|refseq:NP_395173.1|refseq:WP_002212958.1|interpro:IPR010812(Hypersensitivity response secretion HrpJ)|interpro:IPR013401(Type III secretion regulator, YopN/LcrE/InvE/MxiC)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0050709""(negative regulation of protein secretion)|rcsb pdb:1XKP|rcsb pdb:1XL3"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:MKix/cQFqtaeWtEMcnieRrRgypM632	intact-crc:6E58D91A13B25FF3|rigid:K9sJJqLMu/QraD+MHnna6sLsGNo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:P68640	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20817365|uniprotkb:P16160	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:yopn_yerpe(display_long)|uniprotkb:yopN(gene name)|psi-mi:yopN(display_short)|uniprotkb:lcrE(gene name synonym)|uniprotkb:YPCD1.39c(locus name)|uniprotkb:y5039(locus name)|uniprotkb:y0042(locus name)|uniprotkb:YP_pCD44(locus name)|uniprotkb:LcrE(gene name synonym)|uniprotkb:Yop4b(gene name synonym)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817420|imex:IM-26497-590	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	"mint:P68640|refseq:NP_857743.1|refseq:NP_857938.1|refseq:NP_395173.1|refseq:WP_002212958.1|interpro:IPR010812(Hypersensitivity response secretion HrpJ)|interpro:IPR013401(Type III secretion regulator, YopN/LcrE/InvE/MxiC)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0050709""(negative regulation of protein secretion)|rcsb pdb:1XKP|rcsb pdb:1XL3"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:MKix/cQFqtaeWtEMcnieRrRgypM632	intact-crc:C3932430B355886B|rigid:aidtzf0yTO79FAiAaGJ2bP2ZbQw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:P68640	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20817365|uniprotkb:P16160	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:yopn_yerpe(display_long)|uniprotkb:yopN(gene name)|psi-mi:yopN(display_short)|uniprotkb:lcrE(gene name synonym)|uniprotkb:YPCD1.39c(locus name)|uniprotkb:y5039(locus name)|uniprotkb:y0042(locus name)|uniprotkb:YP_pCD44(locus name)|uniprotkb:LcrE(gene name synonym)|uniprotkb:Yop4b(gene name synonym)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817408|imex:IM-26497-548	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"mint:P68640|refseq:NP_857743.1|refseq:NP_857938.1|refseq:NP_395173.1|refseq:WP_002212958.1|interpro:IPR010812(Hypersensitivity response secretion HrpJ)|interpro:IPR013401(Type III secretion regulator, YopN/LcrE/InvE/MxiC)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0050709""(negative regulation of protein secretion)|rcsb pdb:1XKP|rcsb pdb:1XL3"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:MKix/cQFqtaeWtEMcnieRrRgypM632	intact-crc:3626A18FC68901CC|rigid:R5W4I08HmTWXLx0aMWvjn1TDKNU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBX5	uniprotkb:Q7ARI8	intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008.4	intact:EBI-20817426|uniprotkb:A0A0H2W055|uniprotkb:Q74YX5|uniprotkb:Q7BTX3|uniprotkb:A0A384L914|uniprotkb:A0A3N4BJZ3	psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name)	psi-mi:sctn_yerpe(display_long)|uniprotkb:sctN(gene name)|psi-mi:sctN(display_short)|uniprotkb:yscN(gene name synonym)|uniprotkb:Y0041(locus name)|uniprotkb:YPCD1.40(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817454|imex:IM-26497-490	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000140092.16(gene)|ensembl:ENST00000342058.9(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0031012""(extracellular matrix)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046903""(secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000121""(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379|refseq:NP_006320.2|dip:DIP-44301N|efo:""Orphanet:280598""|efo:""Orphanet:90348""|efo:""Orphanet:90349""|panther:PTHR24034(orthology-group)"	"mint:Q7ARI8|interpro:IPR050053|interpro:IPR040627|refseq:NP_395174.1|refseq:NP_857742.1|refseq:NP_857937.1|refseq:WP_002212955.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020003|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR013380(Type III secretion system H+-transporting two-sector ATPase)|interpro:IPR027417|panther:PTHR15184(orthology-group)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/26	rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606	rogid:zHMewjOGsZtAqhlSKb3uM+9wACQ632	intact-crc:A09BC96F4D2BC950|rigid:mjud5UohljvCUoF6ZBzSfL/rUks	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O60711	uniprotkb:P68640	intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512.2	intact:EBI-20817365|uniprotkb:P16160	psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym)	psi-mi:yopn_yerpe(display_long)|uniprotkb:yopN(gene name)|psi-mi:yopN(display_short)|uniprotkb:lcrE(gene name synonym)|uniprotkb:YPCD1.39c(locus name)|uniprotkb:y5039(locus name)|uniprotkb:y0042(locus name)|uniprotkb:YP_pCD44(locus name)|uniprotkb:LcrE(gene name synonym)|uniprotkb:Yop4b(gene name synonym)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817414|imex:IM-26497-748	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137467.1|refseq:NP_004802.1|refseq:NP_001294880.1|ensembl:ENSG00000110031.13(gene)|ensembl:ENST00000395074.7(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042995""(cell projection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|panther:PTHR24216(orthology-group)"	"mint:P68640|refseq:NP_857743.1|refseq:NP_857938.1|refseq:NP_395173.1|refseq:WP_002212958.1|interpro:IPR010812(Hypersensitivity response secretion HrpJ)|interpro:IPR013401(Type III secretion regulator, YopN/LcrE/InvE/MxiC)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0050709""(negative regulation of protein secretion)|rcsb pdb:1XKP|rcsb pdb:1XL3"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606	rogid:MKix/cQFqtaeWtEMcnieRrRgypM632	intact-crc:490CB04BD1964717|rigid:av7mHxvzzDdjSOuqG3k6IhUpuuA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y3M2	uniprotkb:O30878	intact:EBI-947308|uniprotkb:Q66GT6|uniprotkb:Q9UIK9|uniprotkb:B2R4S2|ensembl:ENSP00000216029.3|ensembl:ENSP00000380026.2|ensembl:ENSP00000412260.2|ensembl:ENSP00000413934.2	intact:EBI-2855471|uniprotkb:Q74YX6|uniprotkb:Q7BTX4|uniprotkb:A0A384KF34|uniprotkb:A0A2U2GWF0|uniprotkb:A0A0H2W1I5|uniprotkb:A0A5P8YM42	psi-mi:cby1_human(display_long)|uniprotkb:CBY1(gene name)|psi-mi:CBY1(display_short)|uniprotkb:C22orf2(gene name synonym)|uniprotkb:CBY(gene name synonym)|uniprotkb:HRIHFB2025(orf name)|uniprotkb:ARB1(gene name synonym)|uniprotkb:PGEA1(gene name synonym)|uniprotkb:PKD2 interactor, Golgi and endoplasmic reticulum-associated 1(gene name synonym)|uniprotkb:PIGEA-14(gene name synonym)|uniprotkb:Cytosolic leucine-rich protein(gene name synonym)|uniprotkb:ARPP-binding protein(gene name synonym)	psi-mi:o30878_yerpe(display_long)|uniprotkb:yscO(gene name)|psi-mi:yscO(display_short)|uniprotkb:Y0040(gene name synonym)|uniprotkb:YPCD1.41(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817502|imex:IM-26497-398	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100211.12(gene)|ensembl:ENST00000216029.8(transcript)|ensembl:ENST00000396811.6(transcript)|ensembl:ENST00000411557.6(transcript)|ensembl:ENST00000416285.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008104""(protein localization)|go:""GO:0016607""(nuclear speck)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0033504""(floor plate development)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060271""(cilium assembly)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|interpro:IPR028118|mint:Q9Y3M2|rcsb pdb:4WRQ|reactome:R-HSA-3769402|refseq:NP_001002880.2|refseq:NP_056188.1|dip:DIP-29651N|efo:""Orphanet:475""|panther:PTHR21533(orthology-group)"	interpro:IPR053716|refseq:NP_857741.1|refseq:NP_857936.1|interpro:IPR009929(Type III secretion sytem,YscO)|refseq:NP_395175.1|refseq:WP_002212952.1|mint:O30878	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:RqvyVBe3nAEf0bYnToiVsM5hLhc9606	rogid:ZIfa4PBw2xobcDNWibYatDtfFcI632	intact-crc:9976B8DB0DC3E2B4|rigid:7mGi6w7zdgFs6U56bvSk3CSULGo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05783	uniprotkb:O30878	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	intact:EBI-2855471|uniprotkb:Q74YX6|uniprotkb:Q7BTX4|uniprotkb:A0A384KF34|uniprotkb:A0A2U2GWF0|uniprotkb:A0A0H2W1I5|uniprotkb:A0A5P8YM42	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:o30878_yerpe(display_long)|uniprotkb:yscO(gene name)|psi-mi:yscO(display_short)|uniprotkb:Y0040(gene name synonym)|uniprotkb:YPCD1.41(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817508|imex:IM-26497-452	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	interpro:IPR053716|refseq:NP_857741.1|refseq:NP_857936.1|interpro:IPR009929(Type III secretion sytem,YscO)|refseq:NP_395175.1|refseq:WP_002212952.1|mint:O30878	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:ZIfa4PBw2xobcDNWibYatDtfFcI632	intact-crc:1A5D9E9CD9587CD5|rigid:ZH1EydKMNLljU0bSKu3AXmX/1kk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O15162	uniprotkb:Q7ARI8	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	intact:EBI-20817426|uniprotkb:A0A0H2W055|uniprotkb:Q74YX5|uniprotkb:Q7BTX3|uniprotkb:A0A384L914|uniprotkb:A0A3N4BJZ3	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	psi-mi:sctn_yerpe(display_long)|uniprotkb:sctN(gene name)|psi-mi:sctN(display_short)|uniprotkb:yscN(gene name synonym)|uniprotkb:Y0041(locus name)|uniprotkb:YPCD1.40(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817460|imex:IM-26497-644	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	"mint:Q7ARI8|interpro:IPR050053|interpro:IPR040627|refseq:NP_395174.1|refseq:NP_857742.1|refseq:NP_857937.1|refseq:WP_002212955.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020003|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR013380(Type III secretion system H+-transporting two-sector ATPase)|interpro:IPR027417|panther:PTHR15184(orthology-group)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:zHMewjOGsZtAqhlSKb3uM+9wACQ632	intact-crc:AB4C10FDA25A4E48|rigid:bLCjXE+ehv6F5PIbM32ZxjzF9vM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O60504	uniprotkb:Q7ARI8	intact:EBI-741237|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4|ensembl:ENSP00000240123.7	intact:EBI-20817426|uniprotkb:A0A0H2W055|uniprotkb:Q74YX5|uniprotkb:Q7BTX3|uniprotkb:A0A384L914|uniprotkb:A0A3N4BJZ3	psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short)	psi-mi:sctn_yerpe(display_long)|uniprotkb:sctN(gene name)|psi-mi:sctN(display_short)|uniprotkb:yscN(gene name synonym)|uniprotkb:Y0041(locus name)|uniprotkb:YPCD1.40(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817466|imex:IM-26497-550	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1|ensembl:ENSG00000120896.14(gene)|ensembl:ENST00000240123.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0017166""(vinculin binding)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0051495""(positive regulation of cytoskeleton organization)|go:""GO:0051496""(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|interpro:IPR050384|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|panther:PTHR14167(orthology-group)"	"mint:Q7ARI8|interpro:IPR050053|interpro:IPR040627|refseq:NP_395174.1|refseq:NP_857742.1|refseq:NP_857937.1|refseq:WP_002212955.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020003|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR013380(Type III secretion system H+-transporting two-sector ATPase)|interpro:IPR027417|panther:PTHR15184(orthology-group)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606	rogid:zHMewjOGsZtAqhlSKb3uM+9wACQ632	intact-crc:BE1F8F8E5B95023A|rigid:fnuZDlVHIKqMzHzmXsLW7A2tBBE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q12805	uniprotkb:Q7ARI8	intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|uniprotkb:B4DW75|ensembl:ENSP00000347596.3|ensembl:ENSP00000378058.2	intact:EBI-20817426|uniprotkb:A0A0H2W055|uniprotkb:Q74YX5|uniprotkb:Q7BTX3|uniprotkb:A0A384L914|uniprotkb:A0A3N4BJZ3	psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym)	psi-mi:sctn_yerpe(display_long)|uniprotkb:sctN(gene name)|psi-mi:sctN(display_short)|uniprotkb:yscN(gene name synonym)|uniprotkb:Y0041(locus name)|uniprotkb:YPCD1.40(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817472|imex:IM-26497-592	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24039(orthology-group)|ensembl:ENSG00000115380.20(gene)|ensembl:ENST00000355426.8(transcript)|ensembl:ENST00000394555.6(transcript)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007601""(visual perception)|go:""GO:0008083""(growth factor activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0043010""(camera-type eye development)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1|efo:""Orphanet:75376""|efo:""Orphanet:98977"""	"mint:Q7ARI8|interpro:IPR050053|interpro:IPR040627|refseq:NP_395174.1|refseq:NP_857742.1|refseq:NP_857937.1|refseq:WP_002212955.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020003|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR013380(Type III secretion system H+-transporting two-sector ATPase)|interpro:IPR027417|panther:PTHR15184(orthology-group)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606	rogid:zHMewjOGsZtAqhlSKb3uM+9wACQ632	intact-crc:42461FA4D29F83F5|rigid:FnaKPC02I7Kr/e7hbMSZQoP/kFE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q12805	uniprotkb:O30878	intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|uniprotkb:B4DW75|ensembl:ENSP00000347596.3|ensembl:ENSP00000378058.2	intact:EBI-2855471|uniprotkb:Q74YX6|uniprotkb:Q7BTX4|uniprotkb:A0A384KF34|uniprotkb:A0A2U2GWF0|uniprotkb:A0A0H2W1I5|uniprotkb:A0A5P8YM42	psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym)	psi-mi:o30878_yerpe(display_long)|uniprotkb:yscO(gene name)|psi-mi:yscO(display_short)|uniprotkb:Y0040(gene name synonym)|uniprotkb:YPCD1.41(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817484|imex:IM-26497-396	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24039(orthology-group)|ensembl:ENSG00000115380.20(gene)|ensembl:ENST00000355426.8(transcript)|ensembl:ENST00000394555.6(transcript)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007601""(visual perception)|go:""GO:0008083""(growth factor activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0043010""(camera-type eye development)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1|efo:""Orphanet:75376""|efo:""Orphanet:98977"""	interpro:IPR053716|refseq:NP_857741.1|refseq:NP_857936.1|interpro:IPR009929(Type III secretion sytem,YscO)|refseq:NP_395175.1|refseq:WP_002212952.1|mint:O30878	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606	rogid:ZIfa4PBw2xobcDNWibYatDtfFcI632	intact-crc:162CD62F8F9B06F9|rigid:/y6SvWQjGmQG2aFbKoT40mPAaa4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96BY2	uniprotkb:O30878	intact:EBI-739825|uniprotkb:Q9H833|uniprotkb:Q9HAS1|uniprotkb:B2RDF6|ensembl:ENSP00000298894.4|ensembl:ENSP00000451594.1|ensembl:ENSP00000482284.1|ensembl:ENSP00000486260.1	intact:EBI-2855471|uniprotkb:Q74YX6|uniprotkb:Q7BTX4|uniprotkb:A0A384KF34|uniprotkb:A0A2U2GWF0|uniprotkb:A0A0H2W1I5|uniprotkb:A0A5P8YM42	psi-mi:moap1_human(display_long)|uniprotkb:MOAP1(gene name)|psi-mi:MOAP1(display_short)|uniprotkb:PNMA4(gene name synonym)|uniprotkb:Paraneoplastic antigen Ma4(gene name synonym)	psi-mi:o30878_yerpe(display_long)|uniprotkb:yscO(gene name)|psi-mi:yscO(display_short)|uniprotkb:Y0040(gene name synonym)|uniprotkb:YPCD1.41(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817496|imex:IM-26497-750	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_071434.2|ensembl:ENSG00000165943.5(gene)|ensembl:ENSG00000278268.2(gene)|ensembl:ENST00000298894.5(transcript)|ensembl:ENST00000556883.1(transcript)|ensembl:ENST00000616515.2(transcript)|ensembl:ENST00000627896.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0051204""(protein insertion into mitochondrial membrane)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:2000786""(positive regulation of autophagosome assembly)|interpro:IPR026523|interpro:IPR048270|interpro:IPR048271|mint:Q96BY2|rcsb pdb:7LGC|dip:DIP-49959N|panther:PTHR23095(orthology-group)"	interpro:IPR053716|refseq:NP_857741.1|refseq:NP_857936.1|interpro:IPR009929(Type III secretion sytem,YscO)|refseq:NP_395175.1|refseq:WP_002212952.1|mint:O30878	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/01/09	rogid:wQSSosC82m35M8s+YamN1i73wi49606	rogid:ZIfa4PBw2xobcDNWibYatDtfFcI632	intact-crc:570105B58C444872|rigid:Tu365qRdUaCJ18PYsSr6D3O81qs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15834	uniprotkb:O30878	intact:EBI-739674|uniprotkb:Q96HA0|uniprotkb:B2R598|ensembl:ENSP00000311695.2	intact:EBI-2855471|uniprotkb:Q74YX6|uniprotkb:Q7BTX4|uniprotkb:A0A384KF34|uniprotkb:A0A2U2GWF0|uniprotkb:A0A0H2W1I5|uniprotkb:A0A5P8YM42	psi-mi:cc85b_human(display_long)|uniprotkb:CCDC85B(gene name)|psi-mi:CCDC85B(display_short)|uniprotkb:Hepatitis delta antigen-interacting protein A(gene name synonym)|uniprotkb:DIPA(gene name synonym)	psi-mi:o30878_yerpe(display_long)|uniprotkb:yscO(gene name)|psi-mi:yscO(display_short)|uniprotkb:Y0040(gene name synonym)|uniprotkb:YPCD1.41(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817490|imex:IM-26497-450	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006839.2|ensembl:ENSG00000175602.4(gene)|ensembl:ENST00000312579.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005912""(adherens junction)|go:""GO:0030154""(cell differentiation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070097""(delta-catenin binding)|interpro:IPR019359|mint:Q15834|panther:PTHR13546(orthology-group)"	interpro:IPR053716|refseq:NP_857741.1|refseq:NP_857936.1|interpro:IPR009929(Type III secretion sytem,YscO)|refseq:NP_395175.1|refseq:WP_002212952.1|mint:O30878	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:DUMY8gDRLRjC4Iu+z7SVBZ6sQkY9606	rogid:ZIfa4PBw2xobcDNWibYatDtfFcI632	intact-crc:656FEFB98A4BC7D7|rigid:/M4OGqPqy3ofdrzcdQANlJ1a74g	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:Q7ARI8	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20817426|uniprotkb:A0A0H2W055|uniprotkb:Q74YX5|uniprotkb:Q7BTX3|uniprotkb:A0A384L914|uniprotkb:A0A3N4BJZ3	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:sctn_yerpe(display_long)|uniprotkb:sctN(gene name)|psi-mi:sctN(display_short)|uniprotkb:yscN(gene name synonym)|uniprotkb:Y0041(locus name)|uniprotkb:YPCD1.40(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817478|imex:IM-26497-552	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"mint:Q7ARI8|interpro:IPR050053|interpro:IPR040627|refseq:NP_395174.1|refseq:NP_857742.1|refseq:NP_857937.1|refseq:WP_002212955.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020003|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR013380(Type III secretion system H+-transporting two-sector ATPase)|interpro:IPR027417|panther:PTHR15184(orthology-group)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:zHMewjOGsZtAqhlSKb3uM+9wACQ632	intact-crc:16492F825167A7E6|rigid:Q1s/4HC0689YtLlhl2qDLybDLY4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y228	uniprotkb:P69986	intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991.1|ensembl:ENSP00000355992.3	intact:EBI-2853106|uniprotkb:Q663J2|uniprotkb:P40300	psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym)	psi-mi:yscu_yerpe(display_long)|uniprotkb:yscU(gene name)|psi-mi:yscU(display_short)|uniprotkb:YPCD1.47(locus name)|uniprotkb:y5031(locus name)|uniprotkb:YP_pCD36(locus name)|uniprotkb:y0034(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817547|imex:IM-26497-556	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790.15(gene)|ensembl:ENST00000367024.5(transcript)|ensembl:ENST00000367025.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0060090""(molecular adaptor activity)|interpro:IPR051176|mint:Q9Y228|panther:PTHR15715(orthology-group)"	"interpro:IPR029025|refseq:NP_395181.1|refseq:NP_857735.1|refseq:NP_857930.1|interpro:IPR006307(Type III secretion protein HrpY/HrcU)|interpro:IPR006135(Type III secretion exporter)|refseq:WP_002212936.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|rcsb pdb:2JLH|rcsb pdb:2JLI|rcsb pdb:2JLJ|mint:P69986|panther:PTHR30531(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606	rogid:O8SgavBEJ4hqiIu/b2FwNUny9OM632	intact-crc:F674C8363DA5F869|rigid:hFn4x+zRwGP1qyKLBPPCb1FnEcA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15025	uniprotkb:P69982	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|ensembl:ENSP00000317891.7|ensembl:ENSP00000428187.1|ensembl:ENSP00000428404.2|ensembl:ENSP00000430279.2|ensembl:ENSP00000430760.1|uniprotkb:B7Z699|uniprotkb:Q6N077|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-20817514|uniprotkb:P40298|uniprotkb:P42715|uniprotkb:Q663J4	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:yscs_yerpe(display_long)|uniprotkb:yscS(gene name)|psi-mi:yscS(display_short)|uniprotkb:YPCD1.45(locus name)|uniprotkb:y5033(locus name)|uniprotkb:y0036(locus name)|uniprotkb:YP_pCD38(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817535|imex:IM-26497-554	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000145901.17(gene)|ensembl:ENST00000315050.11(transcript)|ensembl:ENST00000520695.6(transcript)|ensembl:ENST00000521001.2(transcript)|ensembl:ENST00000521591.6(transcript)|ensembl:ENST00000522226.5(transcript)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006412""(translation)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0009101""(glycoprotein biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:1903003""(positive regulation of protein deubiquitination)|mint:Q15025|rcsb pdb:7EAL|rcsb pdb:7EAO|rcsb pdb:7EB9|rcsb pdb:8YFK|rcsb pdb:8YFM|rcsb pdb:8YFN|reactome:R-HSA-5689896|refseq:NP_001239314.1|refseq:NP_001239315.1|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:NP_006049.3|refseq:XP_006714814.1|refseq:XP_006714815.1|dip:DIP-27577N|efo:""Orphanet:536""|panther:PTHR31882(orthology-group)"	"mint:P69982|refseq:NP_395179.1|refseq:NP_857737.1|refseq:NP_857932.1|refseq:WP_002212945.1|interpro:IPR002191(Bacterial export protein FliQ, family 3)|interpro:IPR006306(Type III secretion protein HrpO)|panther:PTHR34040(orthology-group)|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:9NWcWVjPyhhw62xv8k9uB0Xa2PQ632	intact-crc:5D2EEF9959E5CD40|rigid:VhH/R3WYDa+z9y0NrGbfxpG5r/w	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99816	uniprotkb:O68694	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968.3	intact:EBI-20817553|uniprotkb:A0A5P8YNP2|uniprotkb:A0A0H2VZ64|uniprotkb:Q74YX7|uniprotkb:Q7ARI6|uniprotkb:A0A384LFB5|uniprotkb:A0A2U2GVN5	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:o68694_yerpe(display_long)|uniprotkb:virG(gene name)|psi-mi:virG(display_short)|uniprotkb:yscW(gene name synonym)|uniprotkb:Y0033(gene name synonym)|uniprotkb:YPCD1.48(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817571|imex:IM-26497-454	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006283.1|dip:DIP-31809N|panther:PTHR23306(orthology-group)|rcsb pdb:1M4P|ensembl:ENSG00000074319.13(gene)|ensembl:ENST00000251968.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000813""(ESCRT I complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006858""(extracellular transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0019076""(viral release from host cell)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0036211""(protein modification process)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043405""(regulation of MAP kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046755""(viral budding)|go:""GO:0046790""(virion binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0051301""(cell division)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090148""(membrane fission)|go:""GO:0090543""(Flemming body)|go:""GO:0097352""(autophagosome maturation)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903551""(regulation of extracellular exosome assembly)|go:""GO:1903774""(positive regulation of viral budding via host ESCRT complex)|go:""GO:1990182""(exosomal secretion)|go:""GO:2000397""(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|interpro:IPR052070|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|rcsb pdb:7NLC|rcsb pdb:7ZLX|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710"	mint:O68694|interpro:IPR053740|refseq:NP_395182.1|refseq:NP_857734.1|refseq:NP_857929.3|refseq:WP_002222527.1|interpro:IPR039366	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:bdRR5Vdw7vONCFLqc2mRrsSKCn0632	intact-crc:529E98E52599A219|rigid:dM49jWQgpeoqqI19ubN185wqOQQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q04206	uniprotkb:P69982	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	intact:EBI-20817514|uniprotkb:P40298|uniprotkb:P42715|uniprotkb:Q663J4	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:yscs_yerpe(display_long)|uniprotkb:yscS(gene name)|psi-mi:yscS(display_short)|uniprotkb:YPCD1.45(locus name)|uniprotkb:y5033(locus name)|uniprotkb:y0036(locus name)|uniprotkb:YP_pCD38(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817541|imex:IM-26497-752	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	"mint:P69982|refseq:NP_395179.1|refseq:NP_857737.1|refseq:NP_857932.1|refseq:WP_002212945.1|interpro:IPR002191(Bacterial export protein FliQ, family 3)|interpro:IPR006306(Type III secretion protein HrpO)|panther:PTHR34040(orthology-group)|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rogid:9NWcWVjPyhhw62xv8k9uB0Xa2PQ632	intact-crc:B4575AD952810F5C|rigid:uU7M481Vsa07gDMx9D+F7WXaxnA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHD9	uniprotkb:Q56975	intact:EBI-947187|uniprotkb:O94798|uniprotkb:Q9H3W6|uniprotkb:Q9HAZ4|uniprotkb:Q5D027|ensembl:ENSP00000345195.5|intact:EBI-28967571	intact:EBI-6413916|uniprotkb:Q74YX9|uniprotkb:Q7BTX7|uniprotkb:A0A384KEC2|uniprotkb:A0A0H2W058|uniprotkb:A0A380SBC7|uniprotkb:A0A3G5L0Z0|uniprotkb:A0A9Y2Y7E4|uniprotkb:A0A2U2GUL2	psi-mi:ubql2_human(display_long)|uniprotkb:UBQLN2(gene name)|psi-mi:UBQLN2(display_short)|uniprotkb:PLIC2(gene name synonym)|uniprotkb:HRIHFB2157(orf name)|uniprotkb:N4BP4(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 2(gene name synonym)|uniprotkb:Ubiquitin-like product Chap1/Dsk2(gene name synonym)|uniprotkb:DSK2 homolog(gene name synonym)|uniprotkb:Chap1(gene name synonym)	psi-mi:q56975_yerpe(display_long)|uniprotkb:yscD(gene name)|psi-mi:yscD(display_short)|uniprotkb:YPCD1.53(locus name)|uniprotkb:Y0028(gene name synonym)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817613|imex:IM-26497-604	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000188021.9(gene)|ensembl:ENST00000338222.7(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005776""(autophagosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900186""(negative regulation of clathrin-dependent endocytosis)|go:""GO:1904021""(negative regulation of G protein-coupled receptor internalization)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015496(Ubiquilin)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029071|mint:Q9UHD9|rcsb pdb:1J8C|rcsb pdb:2NBV|rcsb pdb:6MUN|rcsb pdb:7F7X|reactome:R-HSA-8856825|refseq:NP_038472.2|dip:DIP-42116N|efo:""Orphanet:803""|panther:PTHR10677(orthology-group)"	"go:""GO:0016020""(membrane)|rcsb pdb:4A0E|interpro:IPR053946|interpro:IPR053947|mint:Q56975|refseq:WP_002212919.1|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012843(Type III secretion system YscD/HrpQ)|refseq:NP_395187.1|refseq:NP_857729.1|refseq:NP_857924.1|interpro:IPR032030|interpro:IPR032034"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/17	rogid:tElcz7gHFkKFVDTz3PXeNcaBP7U9606	rogid:/RZ00PckilfW1XiwoyHOfRpTuiI632	intact-crc:876F01EEDD1796C3|rigid:TQhjltBn+HexcNGs9bKKzBbBuLs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O15162	uniprotkb:Q56973	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	intact:EBI-20592268	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	psi-mi:yscb_yerpe(display_long)|uniprotkb:yscB(gene name)|psi-mi:yscB(display_short)|uniprotkb:Yop proteins translocation protein B(gene name synonym)|uniprotkb:YPCD1.51(locus name)|uniprotkb:YP_pCD32(locus name)|uniprotkb:y0030(locus name)|uniprotkb:y5027(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817595|imex:IM-26497-646	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|rcsb pdb:1XKP|refseq:NP_395185.1|refseq:NP_857731.1|refseq:NP_857926.1|refseq:WP_002212925.1|interpro:IPR013353(Type III secretion system chaperone YscB)|interpro:IPR010261(Tir chaperone)|mint:Q56973"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:Vy7YorWh6UR5bH680AS7SaUyWKs632	intact-crc:E5499FEBEF8357D1|rigid:7nuMpnqtjPvoF0h14V8pJYK+kII	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:Q56973	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20592268	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:yscb_yerpe(display_long)|uniprotkb:yscB(gene name)|psi-mi:yscB(display_short)|uniprotkb:Yop proteins translocation protein B(gene name synonym)|uniprotkb:YPCD1.51(locus name)|uniprotkb:YP_pCD32(locus name)|uniprotkb:y0030(locus name)|uniprotkb:y5027(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817583|imex:IM-26497-558	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|rcsb pdb:1XKP|refseq:NP_395185.1|refseq:NP_857731.1|refseq:NP_857926.1|refseq:WP_002212925.1|interpro:IPR013353(Type III secretion system chaperone YscB)|interpro:IPR010261(Tir chaperone)|mint:Q56973"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:Vy7YorWh6UR5bH680AS7SaUyWKs632	intact-crc:584CA0941CBEBE7F|rigid:dNqDv3u5+7WjxfgWrysGNAB/ACs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43681	uniprotkb:Q56975	intact:EBI-2515857|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109|ensembl:ENSP00000349887.3|ensembl:ENSP00000466379.1	intact:EBI-6413916|uniprotkb:Q74YX9|uniprotkb:Q7BTX7|uniprotkb:A0A384KEC2|uniprotkb:A0A0H2W058|uniprotkb:A0A380SBC7|uniprotkb:A0A3G5L0Z0|uniprotkb:A0A9Y2Y7E4|uniprotkb:A0A2U2GUL2	psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym)	psi-mi:q56975_yerpe(display_long)|uniprotkb:yscD(gene name)|psi-mi:yscD(display_short)|uniprotkb:YPCD1.53(locus name)|uniprotkb:Y0028(gene name synonym)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817619|imex:IM-26497-696	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000198356.12(gene)|ensembl:ENST00000357332.8(transcript)|ensembl:ENST00000591090.5(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0015105""(arsenite transmembrane transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032977""(membrane insertase activity)|go:""GO:0043529""(GET complex)|go:""GO:0045048""(protein insertion into ER membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|rcsb pdb:8CQZ|rcsb pdb:8CR1|rcsb pdb:8CR2|reactome:R-HSA-9609523|refseq:NP_004308.2|efo:""Orphanet:154""|panther:PTHR10803(orthology-group)"	"go:""GO:0016020""(membrane)|rcsb pdb:4A0E|interpro:IPR053946|interpro:IPR053947|mint:Q56975|refseq:WP_002212919.1|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012843(Type III secretion system YscD/HrpQ)|refseq:NP_395187.1|refseq:NP_857729.1|refseq:NP_857924.1|interpro:IPR032030|interpro:IPR032034"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606	rogid:/RZ00PckilfW1XiwoyHOfRpTuiI632	intact-crc:ED20CF8848D3994E|rigid:MK4arSJGVAdc5HccDmCQMs5LPdE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8IY31	uniprotkb:P28808	intact:EBI-744203|uniprotkb:Q5GLZ2|uniprotkb:Q9BUG5|intact:EBI-2561300|uniprotkb:J3QL09|ensembl:ENSP00000378809.3|ensembl:ENSP00000463138.1	intact:EBI-2860941	psi-mi:ift20_human(display_long)|uniprotkb:IFT20(gene name)|psi-mi:IFT20(display_short)	psi-mi:lcrf_yerpe(display_long)|uniprotkb:lcrF(gene name)|psi-mi:lcrF(display_short)|uniprotkb:virF(gene name synonym)|uniprotkb:YPCD1.49(locus name)|uniprotkb:y5029(locus name)|uniprotkb:y0032(locus name)|uniprotkb:YP_pCD34(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817577|imex:IM-26497-602	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001254706.1|refseq:NP_001254707.1|refseq:NP_777547.1|refseq:NP_001254703.1|refseq:NP_001254704.1|refseq:NP_001254705.1|ensembl:ENSG00000109083.14(gene)|ensembl:ENST00000395418.8(transcript)|ensembl:ENST00000585313.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001736""(establishment of planar polarity)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001822""(kidney development)|go:""GO:0002046""(opsin binding)|go:""GO:0002177""(manchette)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005902""(microvillus)|go:""GO:0005929""(cilium)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008542""(visual learning)|go:""GO:0030990""(intraciliary transport particle)|go:""GO:0030992""(intraciliary transport particle B)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031514""(motile cilium)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0032420""(stereocilium)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0035720""(intraciliary anterograde transport)|go:""GO:0035845""(photoreceptor cell outer segment organization)|go:""GO:0036064""(ciliary basal body)|go:""GO:0036372""(opsin transport)|go:""GO:0043005""(neuron projection)|go:""GO:0044292""(dendrite terminus)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045724""(positive regulation of cilium assembly)|go:""GO:0051642""(centrosome localization)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060122""(inner ear receptor cell stereocilium organization)|go:""GO:0060271""(cilium assembly)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0061351""(neural precursor cell proliferation)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090102""(cochlea development)|go:""GO:0097542""(ciliary tip)|go:""GO:0097546""(ciliary base)|go:""GO:0097730""(non-motile cilium)|go:""GO:1902017""(regulation of cilium assembly)|go:""GO:1902636""(kinociliary basal body)|go:""GO:2000583""(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR028172|mint:Q8IY31|reactome:R-HSA-5620924|panther:PTHR31978(orthology-group)"	"refseq:NP_395183.1|refseq:NP_857733.1|refseq:NP_857928.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR018062|interpro:IPR018060|interpro:IPR020449|interpro:IPR054015|mint:P28808|refseq:WP_002212931.1|interpro:IPR050204|interpro:IPR037923|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0043565""(sequence-specific DNA binding)|panther:PTHR43280(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:/sGgagcq0b/YoxjD4Psc7D6jY2Q9606	rogid:yVpO1P2FvEEro9oVZYYjR90kz/M632	intact-crc:D2466079B997FCEB|rigid:c7L2GK/PJwBN98Untw5LKaPLGtc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P21333	uniprotkb:Q56975	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45|ensembl:ENSP00000358866.3	intact:EBI-6413916|uniprotkb:Q74YX9|uniprotkb:Q7BTX7|uniprotkb:A0A384KEC2|uniprotkb:A0A0H2W058|uniprotkb:A0A380SBC7|uniprotkb:A0A3G5L0Z0|uniprotkb:A0A9Y2Y7E4|uniprotkb:A0A2U2GUL2	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:q56975_yerpe(display_long)|uniprotkb:yscD(gene name)|psi-mi:yscD(display_short)|uniprotkb:YPCD1.53(locus name)|uniprotkb:Y0028(gene name synonym)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817607|imex:IM-26497-648	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1826""|efo:""Orphanet:2301""|efo:""Orphanet:2484""|efo:""Orphanet:482606""|efo:""Orphanet:555877""|efo:""Orphanet:75497""|efo:""Orphanet:88630""|efo:""Orphanet:90650""|efo:""Orphanet:90652""|efo:""Orphanet:98892""|efo:""Orphanet:99811""|ensembl:ENSG00000196924.19(gene)|ensembl:ENST00000369850.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002102""(podosome)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007195""(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:""GO:0007597""(blood coagulation, intrinsic pathway)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016479""(negative regulation of transcription by RNA polymerase I)|go:""GO:0019900""(kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031523""(Myb complex)|go:""GO:0032233""(positive regulation of actin filament bundle assembly)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043204""(perikaryon)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0044295""(axonal growth cone)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0046332""(SMAD binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050808""(synapse organization)|go:""GO:0050821""(protein stabilization)|go:""GO:0051015""(actin filament binding)|go:""GO:0051020""(GTPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090042""(tubulin deacetylation)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0097368""(establishment of Sertoli cell barrier)|go:""GO:0097440""(apical dendrite)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901381""(positive regulation of potassium ion transmembrane transport)|go:""GO:1902396""(protein localization to bicellular tight junction)|go:""GO:1905000""(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:""GO:1905031""(regulation of membrane repolarization during cardiac muscle cell action potential)|go:""GO:1990779""(glycoprotein Ib-IX-V complex)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|go:""GO:2001224""(positive regulation of neuron migration)|rcsb pdb:6EW1|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|rcsb pdb:7SC4|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|rcsb pdb:7SFT|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|refseq:NP_001104026.1|refseq:NP_001447.2|dip:DIP-1136N|panther:PTHR38537(orthology-group)"	"go:""GO:0016020""(membrane)|rcsb pdb:4A0E|interpro:IPR053946|interpro:IPR053947|mint:Q56975|refseq:WP_002212919.1|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012843(Type III secretion system YscD/HrpQ)|refseq:NP_395187.1|refseq:NP_857729.1|refseq:NP_857924.1|interpro:IPR032030|interpro:IPR032034"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rogid:/RZ00PckilfW1XiwoyHOfRpTuiI632	intact-crc:4F19209974791177|rigid:gXkT+i3g5RNtDqN+1YDWAZPWPfY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NSC5	uniprotkb:Q56973	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|ensembl:ENSP00000376162.2|ensembl:ENSP00000439937.1|ensembl:ENSP00000446026.1|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-20592268	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:yscb_yerpe(display_long)|uniprotkb:yscB(gene name)|psi-mi:yscB(display_short)|uniprotkb:Yop proteins translocation protein B(gene name synonym)|uniprotkb:YPCD1.51(locus name)|uniprotkb:YP_pCD32(locus name)|uniprotkb:y0030(locus name)|uniprotkb:y5027(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817601|imex:IM-26497-492	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128.19(gene)|ensembl:ENST00000392351.8(transcript)|ensembl:ENST00000539827.5(transcript)|ensembl:ENST00000542541.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0007216""(G protein-coupled glutamate receptor signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030425""(dendrite)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0035256""(G protein-coupled glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045178""(basal part of cell)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2001256""(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|interpro:IPR045027|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|panther:PTHR10918(orthology-group)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|rcsb pdb:1XKP|refseq:NP_395185.1|refseq:NP_857731.1|refseq:NP_857926.1|refseq:WP_002212925.1|interpro:IPR013353(Type III secretion system chaperone YscB)|interpro:IPR010261(Tir chaperone)|mint:Q56973"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:Vy7YorWh6UR5bH680AS7SaUyWKs632	intact-crc:EEA92AF539BA3E79|rigid:EHFlq3xccako5YRCfrWJ7Dy3fz0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99816	uniprotkb:Q56973	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968.3	intact:EBI-20592268	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:yscb_yerpe(display_long)|uniprotkb:yscB(gene name)|psi-mi:yscB(display_short)|uniprotkb:Yop proteins translocation protein B(gene name synonym)|uniprotkb:YPCD1.51(locus name)|uniprotkb:YP_pCD32(locus name)|uniprotkb:y0030(locus name)|uniprotkb:y5027(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817589|imex:IM-26497-754	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006283.1|dip:DIP-31809N|panther:PTHR23306(orthology-group)|rcsb pdb:1M4P|ensembl:ENSG00000074319.13(gene)|ensembl:ENST00000251968.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000813""(ESCRT I complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006858""(extracellular transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0019076""(viral release from host cell)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0036211""(protein modification process)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043405""(regulation of MAP kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046755""(viral budding)|go:""GO:0046790""(virion binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0051301""(cell division)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090148""(membrane fission)|go:""GO:0090543""(Flemming body)|go:""GO:0097352""(autophagosome maturation)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903551""(regulation of extracellular exosome assembly)|go:""GO:1903774""(positive regulation of viral budding via host ESCRT complex)|go:""GO:1990182""(exosomal secretion)|go:""GO:2000397""(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|interpro:IPR052070|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|rcsb pdb:7NLC|rcsb pdb:7ZLX|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710"	"go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|rcsb pdb:1XKP|refseq:NP_395185.1|refseq:NP_857731.1|refseq:NP_857926.1|refseq:WP_002212925.1|interpro:IPR013353(Type III secretion system chaperone YscB)|interpro:IPR010261(Tir chaperone)|mint:Q56973"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:Vy7YorWh6UR5bH680AS7SaUyWKs632	intact-crc:3BC451EB25FA5768|rigid:MKj7rFfXEMpEyaEg9DUFm0jUxDY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O14964	uniprotkb:O68692	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201.4|ensembl:ENSP00000504106.1	intact:EBI-9026446|uniprotkb:Q74YY0|uniprotkb:Q7ARI1|uniprotkb:A0A0H2W050|uniprotkb:A0A384KN33|uniprotkb:A0A380SD15|uniprotkb:A0A2U2GUL9	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:ysce_yerpe(display_long)|uniprotkb:Y0027(gene name synonym)|uniprotkb:yscE(gene name)|psi-mi:yscE(display_short)|uniprotkb:Yersinia secretion component E(gene name synonym)|uniprotkb:Yop proteins translocation protein E(gene name synonym)|uniprotkb:EGX46_00100(orf name)|uniprotkb:YPCD1.54(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817625|imex:IM-26497-756	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004703.1|ensembl:ENSG00000185359.14(gene)|ensembl:ENST00000329138.9(transcript)|ensembl:ENST00000676546.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010324""(membrane invagination)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010642""(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:""GO:0016197""(endosomal transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033565""(ESCRT-0 complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0042176""(regulation of protein catabolic process)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043405""(regulation of MAP kinase activity)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0090148""(membrane fission)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:1903543""(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|dip:DIP-29050N|panther:PTHR46275(orthology-group)"	"interpro:IPR012671(Type III secretion system YseE)|refseq:NP_395188.1|refseq:NP_857728.1|refseq:NP_857923.1|refseq:WP_002212917.1|go:""GO:0005737""(cytoplasm)|rcsb pdb:1ZW0|rcsb pdb:2P58|mint:O68692"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/27	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:zjJMODiv6+B4d9gyFwNzwbujILU632	intact-crc:D1887BD4C8633748|rigid:Y7OVN+8mSeFoXmfNKwwXZjcjVYk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96FS4	uniprotkb:O68690	intact:EBI-1054981|uniprotkb:O14518|uniprotkb:O60484|uniprotkb:O60618|uniprotkb:Q2YD83|ensembl:ENSP00000377771.3|ensembl:ENSP00000436269.1	intact:EBI-9026429|uniprotkb:Q74YY2|uniprotkb:Q7ARH9|uniprotkb:A0A0H2VZ57|uniprotkb:A0A380SCA3|uniprotkb:A0A2S9PEH8	psi-mi:sipa1_human(display_long)|uniprotkb:GTPase-activating protein Spa-1(gene name synonym)|uniprotkb:p130 SPA-1(gene name synonym)|uniprotkb:SIPA1(gene name)|psi-mi:SIPA1(display_short)|uniprotkb:SPA1(gene name synonym)	psi-mi:yscg_yerpe(display_long)|uniprotkb:Y0025(gene name synonym)|uniprotkb:yscG(gene name)|psi-mi:yscG(display_short)|uniprotkb:Yersinia secretion component G(gene name synonym)|uniprotkb:Yop proteins translocation protein G(gene name synonym)|uniprotkb:EGX46_00090(orf name)|uniprotkb:YPCD1.56(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817631|imex:IM-26497-456	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006738.3|refseq:NP_694985.29|refseq:XP_011543516.1|refseq:XP_005274246.1|ensembl:ENSG00000213445.10(gene)|ensembl:ENST00000394224.3(transcript)|ensembl:ENST00000534313.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003382""(epithelial cell morphogenesis)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042631""(cellular response to water deprivation)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0090162""(establishment of epithelial cell polarity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035974|interpro:IPR036034|interpro:IPR050989|mint:Q96FS4|reactome:R-HSA-392517|panther:PTHR15711(orthology-group)"	"interpro:IPR013348(Type III secretion system YscG)|refseq:NP_395190.1|refseq:NP_857726.1|refseq:NP_857921.1|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_002229801.1|go:""GO:0005737""(cytoplasm)|rcsb pdb:2P58|mint:O68690"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:N5g/PMrgPEjYn5Cqv5uo0cAMPJI9606	rogid:oQuF6ZUvUCFAcBLv2sa9l3KSi4I632	intact-crc:9F628C8B6E607C6F|rigid:ptfz6qjq3+Yos2VW/jRlUGNeZtE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:P69970	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-2862764|uniprotkb:Q663I1|uniprotkb:Q00933	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:ysci_yerpe(display_long)|uniprotkb:yscI(gene name)|psi-mi:yscI(display_short)|uniprotkb:lcrO(gene name synonym)|uniprotkb:Low calcium response locus protein O(gene name synonym)|uniprotkb:YPCD1.58(locus name)|uniprotkb:y5020(locus name)|uniprotkb:y0023(locus name)|uniprotkb:YP_pCD25(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817643|imex:IM-26497-494	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	"interpro:IPR012670(Type III secretion system YscI/HrpB)|refseq:NP_395192.1|refseq:NP_857724.1|refseq:NP_857919.1|mint:P69970|refseq:WP_002212914.1|go:""GO:0030254""(protein secretion by the type III secretion system)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:9PW6IwgfB1tJdJQ+NpneS6g3hHg632	intact-crc:9AF7F439377C6241|rigid:1TAW1Shn74GPKbbPY3tHJB8Lxog	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15276	uniprotkb:P68590	intact:EBI-447043|uniprotkb:O95369|uniprotkb:Q8IVX3|uniprotkb:B2RAG7|ensembl:ENSP00000445408.2	intact:EBI-2845098|uniprotkb:Q00929	psi-mi:rabe1_human(display_long)|uniprotkb:Rabaptin-5(gene name synonym)|uniprotkb:Rabaptin-5alpha(gene name synonym)|uniprotkb:Rabaptin-4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-17(gene name synonym)|uniprotkb:RABEP1(gene name)|psi-mi:RABEP1(display_short)|uniprotkb:RABPT5(gene name synonym)|uniprotkb:RABPT5A(gene name synonym)|uniprotkb:RAB5EP(gene name synonym)	psi-mi:yopr_yerpe(display_long)|uniprotkb:yscH(gene name)|psi-mi:yscH(display_short)|uniprotkb:lcrP(gene name synonym)|uniprotkb:Yersinia outer protein R(gene name synonym)|uniprotkb:Yersinia secretion protein H(gene name synonym)|uniprotkb:yopR(gene name synonym)|uniprotkb:YPCD1.57(locus name)|uniprotkb:YP_pCD26(locus name)|uniprotkb:y0024(locus name)|uniprotkb:y5021(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817637|imex:IM-26497-650	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001278510.1|refseq:NP_001077054.1|refseq:NP_004694.2|dip:DIP-29350N|rcsb pdb:1TU3|ensembl:ENSG00000029725.17(gene)|ensembl:ENST00000537505.6(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006915""(apoptotic process)|go:""GO:0008083""(growth factor activity)|go:""GO:0015031""(protein transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055037""(recycling endosome)|go:""GO:0061025""(membrane fusion)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1903441""(protein localization to ciliary membrane)|interpro:IPR003914(Rabaptin)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR018514|mint:Q15276|rcsb pdb:1P4U|rcsb pdb:1X79|rcsb pdb:4N3Y|rcsb pdb:4N3Z|rcsb pdb:4Q9U|reactome:R-HSA-8854214|panther:PTHR31179(orthology-group)"	"interpro:IPR013349(Type III secretion system effector YopR)|refseq:NP_395191.1|refseq:NP_857725.1|refseq:NP_857920.1|go:""GO:0005576""(extracellular region)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|rcsb pdb:1Z21|refseq:WP_002212915.1|mint:P68590|interpro:IPR041814"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/26	rogid:FDHgN8w6jbAPC3iQfeLY6sdLkrs9606	rogid:vLBOGgil8yDmtkZgVzl8ti6IGok632	intact-crc:952FB0E7053A5E71|rigid:dFaB6KWbrbzY26N027aBuGiaGQI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P12757	uniprotkb:P69976	intact:EBI-2902468|uniprotkb:A6NGT1|uniprotkb:O00464|uniprotkb:P12756|uniprotkb:Q07501|uniprotkb:B4DT50|ensembl:ENSP00000259119.4|ensembl:ENSP00000415243.3|ensembl:ENSP00000516712.1	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:skil_human(display_long)|uniprotkb:SKIL(gene name)|psi-mi:SKIL(display_short)|uniprotkb:SNO(gene name synonym)|uniprotkb:Ski-related protein(gene name synonym)|uniprotkb:Ski-related oncogene(gene name synonym)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817715|imex:IM-26497-560	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138569.1|refseq:NP_001138570.1|refseq:NP_005405.2|refseq:NP_001234937.1|refseq:XP_005247778.1|refseq:XP_006713798.1|dip:DIP-42138N|ensembl:ENSG00000136603.15(gene)|ensembl:ENST00000259119.9(transcript)|ensembl:ENST00000458537.7(transcript)|ensembl:ENST00000465590.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001825""(blastocyst formation)|go:""GO:0002260""(lymphocyte homeostasis)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0016605""(PML body)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0046332""(SMAD binding)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050772""(positive regulation of axonogenesis)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070306""(lens fiber cell differentiation)|go:""GO:0070848""(response to growth factor)|go:""GO:1902043""(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1902231""(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR037000|mint:P12757|rcsb pdb:3EQ5|rcsb pdb:5C4V|reactome:R-HSA-2173795|panther:PTHR10005(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/01/22	rogid:CktHHQJKOG+DaY5zwy1U+2YeTmw9606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:3C44518D54A98D3D|rigid:10RNCCRwe5zj1Oc2v/ImBt70K3E	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96EP0	uniprotkb:P69974	intact:EBI-948111|uniprotkb:Q9H5F1|uniprotkb:Q9NWD2|uniprotkb:Q86VI2|uniprotkb:Q8TEI0|uniprotkb:Q96GB4|uniprotkb:Q96NF1|uniprotkb:A0A962|ensembl:ENSP00000315112.6|ensembl:ENSP00000496609.1	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	psi-mi:rnf31_human(display_long)|uniprotkb:Zinc in-between-RING-finger ubiquitin-associated domain protein(gene name synonym)|uniprotkb:RNF31(gene name)|psi-mi:RNF31(display_short)|uniprotkb:ZIBRA(gene name synonym)|uniprotkb:HOIL-1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF31(gene name synonym)	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817649|imex:IM-26497-652	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:6KC5|rcsb pdb:6KC6|rcsb pdb:6SC5|rcsb pdb:6SC6|rcsb pdb:6SC7|rcsb pdb:6SC8|rcsb pdb:6SC9|rcsb pdb:7TV4|rcsb pdb:7UY2|rcsb pdb:7UYJ|rcsb pdb:7UYK|rcsb pdb:7V8F|rcsb pdb:7V8G|rcsb pdb:9AZJ|rcsb pdb:9B0B|rcsb pdb:9B0Z|rcsb pdb:9B12|reactome:R-HSA-5357786|ensembl:ENSG00000092098.18(gene)|ensembl:ENSG00000285152.2(gene)|ensembl:ENST00000324103.11(transcript)|ensembl:ENST00000647495.2(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0036435""(K48-linked polyubiquitin modification-dependent protein binding)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0071797""(LUBAC complex)|go:""GO:0097039""(protein linear polyubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:1904417""(positive regulation of xenophagy)|go:""GO:1990450""(linear polyubiquitin binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018997|interpro:IPR026254|interpro:IPR032065|interpro:IPR036339|interpro:IPR036443|interpro:IPR040641|interpro:IPR041031|interpro:IPR044066|interpro:IPR047539|interpro:IPR047540|interpro:IPR047541|interpro:IPR047542|interpro:IPR047543|mint:Q96EP0|rcsb pdb:2CT7|rcsb pdb:4DBG|rcsb pdb:4JUY|rcsb pdb:4LJO|rcsb pdb:4LJP|rcsb pdb:4LJQ|rcsb pdb:4OWF|rcsb pdb:4OYJ|rcsb pdb:4OYK|rcsb pdb:4P09|rcsb pdb:4P0A|rcsb pdb:4P0B|rcsb pdb:5EDV|rcsb pdb:5LJN|rcsb pdb:5X0W|rcsb pdb:6GZY|reactome:R-HSA-5357905|reactome:R-HSA-5357956|refseq:NP_001297261.1|refseq:NP_060469.4|dip:DIP-44034N|efo:""Orphanet:329173""|panther:PTHR16004(orthology-group)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:5QylozByg2G8/5LnkorkdY5fPec9606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:DC126F871C363F67|rigid:Yl1Zqpr8jvW07KM+iiVn6Wehu1M	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:P69976	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817751|imex:IM-26497-402	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:1F2D2A215740D8C1|rigid:Y6XyhVl/CD28tGPZ1pN2hLEB5uY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05783	uniprotkb:P69974	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817667|imex:IM-26497-654	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:CE509D03D7B366D9|rigid:GH8s8YSjipvOfPsAjJYW5DW5LBY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q4LDE5	uniprotkb:P69974	intact:EBI-2798103|ensembl:ENSP00000363593.2|uniprotkb:Q96JU7|uniprotkb:Q5VTE5|uniprotkb:Q5D213|uniprotkb:Q0P675|uniprotkb:Q9H284|uniprotkb:Q5T938|uniprotkb:Q9H8J9|uniprotkb:Q5VTE4|uniprotkb:Q7Z3G3|uniprotkb:Q7Z387|uniprotkb:Q8NBT9	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	psi-mi:svep1_human(display_long)|uniprotkb:C9orf13(gene name synonym)|uniprotkb:CCP22(gene name synonym)|uniprotkb:SELOB(gene name synonym)|uniprotkb:CCP module-containing protein 22(gene name synonym)|uniprotkb:Polydom(gene name synonym)|uniprotkb:Selectin-like osteoblast-derived protein(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-38(gene name synonym)|uniprotkb:SVEP1(gene name)|psi-mi:SVEP1(display_short)	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817679|imex:IM-26497-498	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165124.19(gene)|ensembl:ENST00000374469.6(transcript)|go:""GO:0003017""(lymph circulation)|go:""GO:0003682""(chromatin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008544""(epidermis development)|go:""GO:0010467""(gene expression)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0016020""(membrane)|go:""GO:0036303""(lymph vessel morphogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0048014""(Tie signaling pathway)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0120193""(tight junction organization)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001759(Pentaxin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003410(Hyalin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011641(GCC2 and GCC3)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR035976|interpro:IPR036465|interpro:IPR049883|interpro:IPR050350|mint:Q4LDE5|refseq:NP_699197.3|panther:PTHR19325(orthology-group)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:Eql8u2cebsRMv79rjBrmS/0b9Ec9606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:C31A35F3EDA7B931|rigid:SJoJjTmC/d/9KO7PSYqbaSp2020	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q16891	uniprotkb:P69974	intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262.3	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name)	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817661|imex:IM-26497-460	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|panther:PTHR15415(orthology-group)|ensembl:ENSG00000132305.22(gene)|ensembl:ENST00000410111.8(transcript)|go:""GO:0001401""(SAM complex)|go:""GO:0003723""(RNA binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0007007""(inner mitochondrial membrane organization)|go:""GO:0016020""(membrane)|go:""GO:0042407""(cristae formation)|go:""GO:0044284""(mitochondrial crista junction)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:0061617""(MICOS complex)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0140275""(MIB complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|refseq:XP_016858683.1|dip:DIP-32517N"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:FB9B89E386C6C9FC|rigid:f5GyXXPkV6SgsyuvafjyO2g7OwA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8N2Y8	uniprotkb:P69976	intact:EBI-722486|uniprotkb:A2RU62|uniprotkb:O15080|uniprotkb:Q5W134|uniprotkb:Q641Q6|uniprotkb:Q6P1W7|uniprotkb:A7E2A9|ensembl:ENSP00000355177.3|ensembl:ENSP00000393922.1|intact:EBI-28984356	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:rusc2_human(display_long)|uniprotkb:Interacting protein of Rab1(gene name synonym)|uniprotkb:RUN and SH3 domain-containing protein 2(gene name synonym)|uniprotkb:RUSC2(gene name)|psi-mi:RUSC2(display_short)|uniprotkb:KIAA0375(gene name synonym)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817709|imex:IM-26497-704	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001129471.1|ensembl:ENSG00000198853.12(gene)|ensembl:ENST00000361226.8(transcript)|ensembl:ENST00000455600.1(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR004012(RUN)|interpro:IPR036028|interpro:IPR037213|interpro:IPR047342|interpro:IPR047343|mint:Q8N2Y8|rcsb pdb:6IF2|refseq:NP_055621.1|panther:PTHR15591(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:gsqwJAaLhTQY9djQ3GBVXlCPuYQ9606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:18FBAC97FC029F6D|rigid:NFDC1X7P+NwSQbZjiOZ4QwXt9UI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O15162	uniprotkb:P69974	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817691|imex:IM-26497-698	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:2B2BDAE9F1B5D148|rigid:kvov8BIuJVuyYWG//UR65ugqhHU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02792	uniprotkb:P69976	intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0|ensembl:ENSP00000366525.2	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817739|imex:IM-26497-758	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:157846""|efo:""Orphanet:163""|efo:""Orphanet:254704""|efo:""Orphanet:440731""|ensembl:ENSG00000087086.16(gene)|ensembl:ENST00000331825.11(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005776""(autophagosome)|go:""GO:0005829""(cytosol)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008199""(ferric iron binding)|go:""GO:0016020""(membrane)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0044754""(autolysosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070288""(ferritin complex)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|refseq:NP_000137.2|dip:DIP-31248N|panther:PTHR11431(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:97BFDD5748573F0A|rigid:4W89uH5CAjLjebJmc3R17YXtwfk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BTD8	uniprotkb:P69976	intact:EBI-746862|ensembl:ENSP00000262633.3|uniprotkb:O00320|uniprotkb:Q8N5R7|uniprotkb:Q9BU66	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:rbm42_human(display_long)|uniprotkb:RNA-binding motif protein 42(gene name synonym)|uniprotkb:RBM42(gene name)|psi-mi:RBM42(display_short)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817703|imex:IM-26497-462	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR034215|ensembl:ENSG00000126254.12(gene)|ensembl:ENST00000262633.9(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0048025""(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR050825|mint:Q9BTD8|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8QP8|rcsb pdb:8QP9|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8R08|rcsb pdb:8R0A|reactome:R-HSA-72163|refseq:NP_001306042.1|refseq:NP_077297.2|panther:PTHR47640(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:lZboYvefRzyEBdGJKGGrWJEyV0g9606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:BC77F3FAD589B8CF|rigid:3BA7mMymCKrsUDF76mG6GxH3JmE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q03014	uniprotkb:P69974	intact:EBI-747421|uniprotkb:Q96CE9|ensembl:ENSP00000282728.5|uniprotkb:B1AQ17	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	psi-mi:hhex_human(display_long)|uniprotkb:HEX(gene name synonym)|uniprotkb:PRH(gene name synonym)|uniprotkb:PRHX(gene name synonym)|uniprotkb:HHEX(gene name)|psi-mi:HHEX(display_short)|uniprotkb:Homeobox protein PRH(gene name synonym)|uniprotkb:Proline-rich homeodomain protein(gene name synonym)	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817655|imex:IM-26497-458	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000152804.11(gene)|refseq:NP_002720.1|ensembl:ENST00000282728.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0008190""(eukaryotic initiation factor 4E binding)|go:""GO:0008301""(DNA binding, bending)|go:""GO:0009952""(anterior/posterior pattern specification)|go:""GO:0010621""(negative regulation of transcription by transcription factor localization)|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0016604""(nuclear body)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0017025""(TBP-class protein binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045736""(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070663""(regulation of leukocyte proliferation)|go:""GO:0071103""(DNA conformation change)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR051000|mint:Q03014|rcsb pdb:2E1O|panther:PTHR24324(orthology-group)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:TzAdimtpe4BiHU8+dLnbcznkHDA9606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:0318302F3FB10A80|rigid:vJksW/Z5bfWGqzSfidlzy97t4Jk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q4LDE5	uniprotkb:P69976	intact:EBI-2798103|ensembl:ENSP00000363593.2|uniprotkb:Q96JU7|uniprotkb:Q5VTE5|uniprotkb:Q5D213|uniprotkb:Q0P675|uniprotkb:Q9H284|uniprotkb:Q5T938|uniprotkb:Q9H8J9|uniprotkb:Q5VTE4|uniprotkb:Q7Z3G3|uniprotkb:Q7Z387|uniprotkb:Q8NBT9	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:svep1_human(display_long)|uniprotkb:C9orf13(gene name synonym)|uniprotkb:CCP22(gene name synonym)|uniprotkb:SELOB(gene name synonym)|uniprotkb:CCP module-containing protein 22(gene name synonym)|uniprotkb:Polydom(gene name synonym)|uniprotkb:Selectin-like osteoblast-derived protein(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-38(gene name synonym)|uniprotkb:SVEP1(gene name)|psi-mi:SVEP1(display_short)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817721|imex:IM-26497-606	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165124.19(gene)|ensembl:ENST00000374469.6(transcript)|go:""GO:0003017""(lymph circulation)|go:""GO:0003682""(chromatin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008544""(epidermis development)|go:""GO:0010467""(gene expression)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0016020""(membrane)|go:""GO:0036303""(lymph vessel morphogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0048014""(Tie signaling pathway)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0120193""(tight junction organization)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001759(Pentaxin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003410(Hyalin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011641(GCC2 and GCC3)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR035976|interpro:IPR036465|interpro:IPR049883|interpro:IPR050350|mint:Q4LDE5|refseq:NP_699197.3|panther:PTHR19325(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:Eql8u2cebsRMv79rjBrmS/0b9Ec9606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:BFAC7FFBCDB3D0B1|rigid:Dm4BfbPW1w8oxvXJIiSd/Ov1k/Y	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBX5	uniprotkb:P69976	intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008.4	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817757|imex:IM-26497-706	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000140092.16(gene)|ensembl:ENST00000342058.9(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0031012""(extracellular matrix)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046903""(secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000121""(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379|refseq:NP_006320.2|dip:DIP-44301N|efo:""Orphanet:280598""|efo:""Orphanet:90348""|efo:""Orphanet:90349""|panther:PTHR24034(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/26	rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:5C4A49733ED03FD0|rigid:yKG2VopbNtkAkRmplvNYyVpekB4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13227	uniprotkb:P69976	intact:EBI-713355|uniprotkb:Q6FHM8|ensembl:ENSP00000370104.2|ensembl:ENSP00000379841.4|ensembl:ENSP00000500255.1|ensembl:ENSP00000500677.1|uniprotkb:B4DXA1	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:gps2_human(display_long)|uniprotkb:GPS2(gene name)|psi-mi:GPS2(display_short)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817745|imex:IM-26497-562	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004480.1|ensembl:ENSG00000132522.16(gene)|ensembl:ENSG00000288325.1(gene)|ensembl:ENST00000380728.7(transcript)|ensembl:ENST00000389167.9(transcript)|ensembl:ENST00000672046.1(transcript)|ensembl:ENST00000673265.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007254""(JNK cascade)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030332""(cyclin binding)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0035360""(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:""GO:0045598""(regulation of fat cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0098780""(response to mitochondrial depolarisation)|go:""GO:1900045""(negative regulation of protein K63-linked ubiquitination)|interpro:IPR026094|mint:Q13227|rcsb pdb:2L5G|reactome:R-HSA-1989781|reactome:R-HSA-3214815|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9841922|dip:DIP-34427N|panther:PTHR22654(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/01/24	rogid:zMNwbPfMT2dBTxgcwiMD92QHJtM9606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:83825ECFBD7C0275|rigid:LC12y8iopXY3lvSZeectjSmqvE8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P48634	uniprotkb:P69976	intact:EBI-347545|uniprotkb:Q05BK4|uniprotkb:Q4LE37|uniprotkb:Q8MGQ9|uniprotkb:O95875|uniprotkb:Q5SQ29|uniprotkb:Q5SQ30|uniprotkb:Q5ST84|uniprotkb:Q5STX6|uniprotkb:Q5STX7|uniprotkb:Q68DW9|uniprotkb:Q6P9P7|uniprotkb:Q6PIN1|uniprotkb:Q96QC6|uniprotkb:B0UZL3|uniprotkb:B0UZE9|uniprotkb:B0UX77|ensembl:ENSP00000365175.4|ensembl:ENSP00000365201.2|ensembl:ENSP00000372947.2|ensembl:ENSP00000372956.4|ensembl:ENSP00000387477.2|ensembl:ENSP00000387910.1|ensembl:ENSP00000396812.2|ensembl:ENSP00000400540.2|ensembl:ENSP00000404619.1|ensembl:ENSP00000408226.1|ensembl:ENSP00000409444.2|ensembl:ENSP00000413977.2|ensembl:ENSP00000415182.1|ensembl:ENSP00000415363.1	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:prc2a_human(display_long)|uniprotkb:HLA-B-associated transcript 2(gene name synonym)|uniprotkb:PRRC2A(gene name)|psi-mi:PRRC2A(display_short)|uniprotkb:G2(gene name synonym)|uniprotkb:Protein G2(gene name synonym)|uniprotkb:BAT2(gene name synonym)|uniprotkb:Large proline-rich protein BAT2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2A(gene name synonym)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817733|imex:IM-26497-466	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_542417.2|refseq:NP_004629.3|ensembl:ENSG00000204469.13(gene)|ensembl:ENSG00000206427.11(gene)|ensembl:ENSG00000225164.9(gene)|ensembl:ENSG00000225748.9(gene)|ensembl:ENSG00000226618.9(gene)|ensembl:ENSG00000231370.9(gene)|ensembl:ENSG00000231825.9(gene)|ensembl:ENST00000376007.8(transcript)|ensembl:ENST00000376033.3(transcript)|ensembl:ENST00000383455.2(transcript)|ensembl:ENST00000383464.8(transcript)|ensembl:ENST00000414956.1(transcript)|ensembl:ENST00000416335.1(transcript)|ensembl:ENST00000422962.1(transcript)|ensembl:ENST00000428775.1(transcript)|ensembl:ENST00000430737.6(transcript)|ensembl:ENST00000432252.1(transcript)|ensembl:ENST00000435971.6(transcript)|ensembl:ENST00000439762.6(transcript)|ensembl:ENST00000454306.6(transcript)|ensembl:ENST00000458561.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:P48634|panther:PTHR14038(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:6XZhA7FHJ4ckoWPf1yI/OnaNwjo9606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:18A12C48E348C4B8|rigid:b1liaTwrWmRA2+VOPJllNBpJ/7Y	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:P69974	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817685|imex:IM-26497-400	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:639B60297754B141|rigid:LzDjE+wfLkp/IYn5nVI0yXR33pQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8NEU8	uniprotkb:P69976	intact:EBI-741261|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5|ensembl:ENSP00000258530.3	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817727|imex:IM-26497-464	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060641.2|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1|refseq:XP_016875042.1|ensembl:ENSG00000136044.12(gene)|ensembl:ENST00000258530.8(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0002024""(diet induced thermogenesis)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0009631""(cold acclimation)|go:""GO:0010008""(endosome membrane)|go:""GO:0010762""(regulation of fibroblast migration)|go:""GO:0016020""(membrane)|go:""GO:0023052""(signaling)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032009""(early phagosome)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033211""(adiponectin-activated signaling pathway)|go:""GO:0034143""(regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0036186""(early phagosome membrane)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044354""(macropinosome)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045088""(regulation of innate immune response)|go:""GO:0046322""(negative regulation of fatty acid oxidation)|go:""GO:0046325""(negative regulation of D-glucose import)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1900016""(negative regulation of cytokine production involved in inflammatory response)|go:""GO:1900077""(negative regulation of cellular response to insulin stimulus)|go:""GO:1905303""(positive regulation of macropinocytosis)|go:""GO:1905451""(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000178""(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004148(BAR)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR047181|interpro:IPR047236|interpro:IPR047237|interpro:IPR047239|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|panther:PTHR46415(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:5B76F27F1A31C4E9|rigid:ttiBfWk534MB0L3pjtCRn2j6g5c	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q13077	uniprotkb:P69974	intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994.3|ensembl:ENSP00000443183.1	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym)	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817697|imex:IM-26497-702	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558.11(gene)|ensembl:ENST00000373887.8(transcript)|ensembl:ENST00000540010.1(transcript)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:2001236""(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR032070|interpro:IPR037306|interpro:IPR049342|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956|panther:PTHR10131(orthology-group)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:0C1B665F6F90FE81|rigid:63rWJJIm3ad1eOOI1zu6qqGK2Cs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q12805	uniprotkb:P69974	intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|uniprotkb:B4DW75|ensembl:ENSP00000347596.3|ensembl:ENSP00000378058.2	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym)	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817673|imex:IM-26497-496	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24039(orthology-group)|ensembl:ENSG00000115380.20(gene)|ensembl:ENST00000355426.8(transcript)|ensembl:ENST00000394555.6(transcript)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007601""(visual perception)|go:""GO:0008083""(growth factor activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0043010""(camera-type eye development)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1|efo:""Orphanet:75376""|efo:""Orphanet:98977"""	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:C221D5B081701CF5|rigid:AcpdPDVcQ3FSbUE8OqmigCvNwag	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q04206	uniprotkb:P69976	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817763|imex:IM-26497-564	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:2072961A2E59BB74|rigid:jeWbOKx11xz2QQbLllkaURGyn0E	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P63172	uniprotkb:Q9RI13	intact:EBI-1176455|uniprotkb:Q15763|uniprotkb:Q5VTU4|ensembl:ENSP00000356056.3	intact:EBI-20817769|uniprotkb:A0A3G5L5B2	psi-mi:dylt1_human(display_long)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym)|uniprotkb:Protein CW-1(gene name synonym)|uniprotkb:DYNLT1(gene name)|psi-mi:DYNLT1(display_short)|uniprotkb:TCTEL1(gene name synonym)|uniprotkb:TCTEX1(gene name synonym)|uniprotkb:TCTEX-1(gene name synonym)	psi-mi:q9ri13_yerpe(display_long)|uniprotkb:yopP(gene name)|psi-mi:yopP(display_short)|uniprotkb:yopJ(gene name synonym)|uniprotkb:YPCD1.71c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817776|imex:IM-26497-502	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006510.1|panther:PTHR21255(orthology-group)|dip:DIP-35251N|ensembl:ENSG00000146425.11(gene)|ensembl:ENST00000367089.8(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007399""(nervous system development)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0019060""(intracellular transport of viral protein in host cell)|go:""GO:0030286""(dynein complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043657""(host cell)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051301""(cell division)|go:""GO:0075521""(microtubule-dependent intracellular transport of viral material towards nucleus)|go:""GO:0099503""(secretory vesicle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|mint:P63172|rcsb pdb:5JPW|rcsb pdb:8J07|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGI|reactome:R-HSA-6798695"	"mint:Q9RI13|refseq:NP_395205.1|refseq:WP_002213287.1|interpro:IPR005083(Serine/Threonine acetyltransferase, YopJ)|go:""GO:0000822""(inositol hexakisphosphate binding)|go:""GO:0016413""(O-acetyltransferase activity)|go:""GO:0090729""(toxin activity)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/28	rogid:RKVyHgf4iNjcY6GfLdIukFOFE+s9606	rogid:nAlKx8BsKAZt6rVrH2O34+3cdqs632	intact-crc:6AFA5DAFBED46C52|rigid:BLwSUt4iBqLzkHK/A7c2hnWghIc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P39023	uniprotkb:Q9RI12	intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001.3	intact:EBI-2849107|uniprotkb:O68717	psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name)|uniprotkb:60S ribosomal protein L3(gene name synonym)	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817782|imex:IM-26497-608	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000958.1|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR1|rcsb pdb:8IR3|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8OJ8|rcsb pdb:8QFD|rcsb pdb:8QOI|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9G8M|rcsb pdb:9GMO|ensembl:ENSG00000100316.16(gene)|ensembl:ENST00000216146.9(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0022625""(cytosolic large ribosomal subunit)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0032991""(protein-containing complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071353""(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|interpro:IPR044892|interpro:IPR045077|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:7F5S|rcsb pdb:7QVP|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8A3D|rcsb pdb:8FKP|rcsb pdb:8FKQ|rcsb pdb:8FKR|rcsb pdb:8FKS|rcsb pdb:8FKT|rcsb pdb:8FKU|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|rcsb pdb:8FKZ|rcsb pdb:8FL0|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FL9|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLC|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8FLF|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IDT|rcsb pdb:8IDY|rcsb pdb:8IE3|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8INK|rcsb pdb:8IPD|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|panther:PTHR11363(orthology-group)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	intact-crc:CD4A38D81B26BCEB|rigid:Dbn9PPNF8SQfePGFu8dZ/wWQ4Zk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q86X55	uniprotkb:A0A1U8QN96	intact:EBI-2339854|uniprotkb:A6NN38|ensembl:ENSP00000325690.4	intact:EBI-20592362|uniprotkb:O68745|uniprotkb:Q74YN8|uniprotkb:Q7ARE5	psi-mi:carm1_human(display_long)|uniprotkb:CARM1(gene name)|psi-mi:CARM1(display_short)|uniprotkb:PRMT4(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 4(gene name synonym)|uniprotkb:Coactivator-associated arginine methyltransferase 1(gene name synonym)	psi-mi:a0a1u8qn96_yerpe(display_long)|uniprotkb:YPMT1.27c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817866|imex:IM-26497-760	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_954592.1|refseq:XP_005259765.1|dip:DIP-44071N|ensembl:ENSG00000142453.13(gene)|ensembl:ENST00000327064.9(transcript)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008276""(protein methyltransferase activity)|interpro:IPR011993(Pleckstrin homology-type)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008469""(histone arginine N-methyltransferase activity)|go:""GO:0016274""(protein-arginine N-methyltransferase activity)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032259""(methylation)|go:""GO:0033146""(regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0035242""(protein-arginine omega-N asymmetric methyltransferase activity)|go:""GO:0035642""(histone H3R17 methyltransferase activity)|go:""GO:0042054""(histone methyltransferase activity)|go:""GO:0043596""(nuclear replication fork)|go:""GO:0044020""(histone H4R3 methyltransferase activity)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0045943""(positive regulation of transcription by RNA polymerase I)|go:""GO:0051591""(response to cAMP)|go:""GO:0062122""(histone H3K37 methyltransferase activity)|go:""GO:0070577""(lysine-acetylated histone binding)|go:""GO:0070611""(histone H3R2 methyltransferase activity)|go:""GO:0071932""(replication fork reversal)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140592""(histone H3R8 methyltransferase activity)|go:""GO:0140759""(histone H3K56 methyltransferase activity)|go:""GO:0140903""(histone H3R26 methyltransferase activity)|go:""GO:0140984""(histone H4K12 methyltransferase activity)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|go:""GO:1990259""(histone H2A Q104 methyltransferase activity)|go:""GO:2000171""(negative regulation of dendrite development)|interpro:IPR020989|interpro:IPR025799|interpro:IPR029063|interpro:IPR055135|mint:Q86X55|rcsb pdb:2Y1W|rcsb pdb:2Y1X|rcsb pdb:4IKP|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5DXJ|rcsb pdb:5U4X|rcsb pdb:6ARJ|rcsb pdb:6ARV|rcsb pdb:6D2L|rcsb pdb:6DVR|rcsb pdb:6IZQ|rcsb pdb:6S70|rcsb pdb:6S71|rcsb pdb:6S74|rcsb pdb:6S77|rcsb pdb:6S79|rcsb pdb:6S7A|rcsb pdb:6S7B|rcsb pdb:6S7C|rcsb pdb:7FAI|rcsb pdb:7FAJ|rcsb pdb:7U9I|rcsb pdb:8G2H|rcsb pdb:8G2I|rcsb pdb:8SIG|rcsb pdb:8SIH|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-6804114|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|panther:PTHR11006(orthology-group)"	"go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055085""(transmembrane transport)|interpro:IPR015854(ABC transporter, lipoprotein release, LolD)|refseq:NP_395365.2|refseq:YP_093906.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR027417|interpro:IPR025662|mint:A0A1U8QN96"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/01/07	rogid:1x1bUjqcA/ZpmrSsSM545ReYH2A9606	rogid:FqRfJOD7v8FxU5HP/gF/YtZLhBY632	intact-crc:542BA8B30B58E219|rigid:svwfJlJ1QsNVCSZhRvNSCdaIQtw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43294	uniprotkb:O68743	intact:EBI-1051449|uniprotkb:Q9BPW3|uniprotkb:Q9Y2V5|uniprotkb:B2R8D5|ensembl:ENSP00000378332.3	intact:EBI-2849869|uniprotkb:A0A384L9N9|uniprotkb:Q74YP1|uniprotkb:Q7ARA6|uniprotkb:Q7BT23|uniprotkb:Q65AP4|uniprotkb:A0A1U8QGX5|uniprotkb:A0A5P8YM11|uniprotkb:A0A2U2H133	psi-mi:tgfi1_human(display_long)|uniprotkb:TGFB1I1(gene name)|psi-mi:TGFB1I1(display_short)|uniprotkb:ARA55(gene name synonym)|uniprotkb:Hydrogen peroxide-inducible clone 5 protein(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 55 kDa(gene name synonym)|uniprotkb:Androgen receptor coactivator 55 kDa protein(gene name synonym)	psi-mi:o68743_yerpe(display_long)|uniprotkb:YPMT1.25Ac(gene name)|psi-mi:YPMT1.25Ac(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817860|imex:IM-26497-662	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035919.1|refseq:NP_001158191.1|refseq:NP_057011.2|dip:DIP-5931N|ensembl:ENSG00000140682.19(gene)|ensembl:ENST00000394863.8(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0016363""(nuclear matrix)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045165""(cell fate commitment)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048495""(Roundabout binding)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0070411""(I-SMAD binding)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|interpro:IPR047075|mint:O43294|panther:PTHR24216(orthology-group)"	"refseq:NP_857662.1|refseq:NP_395362.1|refseq:YP_093903.1|refseq:WP_000176291.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:O68743"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:ekkGbwdFenBhBn0HzJjd4Szi61U9606	rogid:/jUgpNFZ2rE3SwY62pqgY9qM8xs632	intact-crc:8F4FB4475AB3FEFC|rigid:KAHFaw4jaWGDlNHoMkJw56+D/eA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:A0A2U2H157	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20817836|uniprotkb:A0A380PI74|uniprotkb:O68741|uniprotkb:Q74YP3|uniprotkb:A0A1U8QXE4|uniprotkb:A0A384L3Y2|uniprotkb:Q7ARE8	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:a0a2u2h157_yerpe(display_long)|uniprotkb:YPMT1.24c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817854|imex:IM-26497-406	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"refseq:YP_093901.1|refseq:NP_395360.1|refseq:WP_002211787.1|interpro:IPR027417|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:A0A2U2H157"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:ZBT2DT2+eVDyZqugi1iJGAPK7yE632	intact-crc:5761DCDE0245A4EC|rigid:sD1pE/a4GAh/IunaJYCUFUFxBms	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P36404	uniprotkb:A0A2U2H1V0	intact:EBI-752365|ensembl:ENSP00000246747.4|ensembl:ENSP00000436021.1|uniprotkb:Q9BUK8|uniprotkb:G3V184	intact:EBI-20817872|uniprotkb:A0A5P8YNF6|uniprotkb:A0A380PIB3|uniprotkb:A0A0H2W0F6|uniprotkb:Q74YL4|uniprotkb:A0A384KI65|uniprotkb:Q9RID3	psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short)	psi-mi:a0a2u2h1v0_yerpe(display_long)|uniprotkb:YMT1.42Ac(gene name)|psi-mi:YMT1.42Ac(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817887|imex:IM-26497-504	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000213465.8(gene)|ensembl:ENST00000246747.9(transcript)|ensembl:ENST00000529384.5(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006110""(regulation of glycolytic process)|go:""GO:0006457""(protein folding)|go:""GO:0007098""(centrosome cycle)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019003""(GDP binding)|go:""GO:0031113""(regulation of microtubule polymerization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0034260""(negative regulation of GTPase activity)|go:""GO:0051457""(maintenance of protein location in nucleus)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:1903715""(regulation of aerobic respiration)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|interpro:IPR045873|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002|refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|panther:PTHR45697(orthology-group)"	"refseq:NP_395383.1|refseq:YP_093929.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:A0A2U2H1V0"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/28	rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606	rogid:Y6BwO6B/qYza7nE/Xxp1jMICjfY632	intact-crc:CEFF5AAA87ADC5AC|rigid:e4YKmi1IIZPkaCCEwvsPW6F0GEw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P60709	uniprotkb:Q9RI12	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|ensembl:ENSP00000494269.1|ensembl:ENSP00000494750.1|ensembl:ENSP00000495995.2|ensembl:ENSP00000501862.1|ensembl:ENSP00000502821.1|uniprotkb:Q96HG5	intact:EBI-2849107|uniprotkb:O68717	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817794|imex:IM-26497-658	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:673556""|efo:""Orphanet:674653""|ensembl:ENSG00000075624.17(gene)|ensembl:ENST00000493945.6(transcript)|ensembl:ENST00000642480.2(transcript)|ensembl:ENST00000646664.1(transcript)|ensembl:ENST00000674681.1(transcript)|ensembl:ENST00000675515.1(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0000786""(nucleosome)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007409""(axonogenesis)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019894""(kinesin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0022898""(regulation of transmembrane transporter activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030424""(axon)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0035060""(brahma complex)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045176""(apical protein localization)|go:""GO:0045202""(synapse)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048156""(tau protein binding)|go:""GO:0048870""(cell motility)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051621""(regulation of norepinephrine uptake)|go:""GO:0051623""(positive regulation of norepinephrine uptake)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070160""(tight junction)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071564""(npBAF complex)|go:""GO:0071565""(nBAF complex)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0072562""(blood microparticle)|go:""GO:0072749""(cellular response to cytochalasin B)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140092""(bBAF complex)|go:""GO:0140288""(GBAF complex)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000779""(regulation of double-strand break repair)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|rcsb pdb:7P1H|rcsb pdb:7QJ6|rcsb pdb:7QJ9|rcsb pdb:7VDV|rcsb pdb:7W28|rcsb pdb:7W29|rcsb pdb:7Y8R|rcsb pdb:7ZTC|rcsb pdb:7ZTD|rcsb pdb:8COG|rcsb pdb:8DNH|rcsb pdb:8IB8|rcsb pdb:8OI8|rcsb pdb:8OID|rcsb pdb:8QR1|rcsb pdb:8RTT|rcsb pdb:8RTY|rcsb pdb:8RU2|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|rcsb pdb:8XVT|rcsb pdb:9C57|rcsb pdb:9C62|rcsb pdb:9C6N|rcsb pdb:9FJM|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-9824585|reactome:R-HSA-983231|reactome:R-HSA-9845323|refseq:NP_001092.1|efo:""Orphanet:2995""|efo:""Orphanet:64755""|efo:""Orphanet:79107""|dip:DIP-29686N|panther:PTHR11937(orthology-group)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/27	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	intact-crc:4C4FFC8C99100459|rigid:DMGu9jzpPec88tfy1lIVmu8TkUw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08670	uniprotkb:A0A380SDB2	intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|ensembl:ENSP00000224237.5|ensembl:ENSP00000446007.1|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4	intact:EBI-20817806|uniprotkb:Q74YY9|uniprotkb:Q9RI11|uniprotkb:A0A0H2W149|uniprotkb:A0A384KFS7	psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short)	psi-mi:a0a380sdb2_yerpe(display_long)|uniprotkb:Y0008(gene name)|psi-mi:Y0008(display_short)|uniprotkb:YPCD1.73c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817817|imex:IM-26497-404	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:675396""|ensembl:ENSG00000026025.16(gene)|ensembl:ENST00000224237.9(transcript)|ensembl:ENST00000544301.7(transcript)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005212""(structural constituent of eye lens)|go:""GO:0005737""(cytoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0014002""(astrocyte development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030424""(axon)|go:""GO:0031175""(neuron projection development)|go:""GO:0031252""(cell leading edge)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0045109""(intermediate filament organization)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070307""(lens fiber cell development)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071225""(cellular response to muramyl dipeptide)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0097110""(scaffold protein binding)|go:""GO:1990254""(keratin filament binding)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|interpro:IPR050405|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|rcsb pdb:8RVE|rcsb pdb:8TRQ|rcsb pdb:8TRR|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:NP_003371.2|refseq:XP_006717563.1|efo:""Orphanet:98984""|dip:DIP-32507N|panther:PTHR45652(orthology-group)"	mint:A0A380SDB2|refseq:NP_395207.1|refseq:WP_002229809.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606	rogid:QzeTh7SrtYQ1M2durlp37wxVh9Y632	intact-crc:53117339D3E921FB|rigid:kaommTZ8zVCEMs2ROWsHIyP1bJ0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P50552	uniprotkb:Q9RI12	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|ensembl:ENSP00000245932.5|intact:EBI-28992147	intact:EBI-2849107|uniprotkb:O68717	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817800|imex:IM-26497-660	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003361.1|ensembl:ENSG00000125753.15(gene)|ensembl:ENST00000245932.11(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007411""(axon guidance)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031527""(filopodium membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|mint:P50552|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR038023|rcsb pdb:1EGX|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:8GAT|rcsb pdb:8GAU|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N|panther:PTHR11202(orthology-group)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/28	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	intact-crc:06D6027C3789B698|rigid:4Z5QmUj15MM5D/iOO3yGcpUQ41o	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UI08	uniprotkb:Q9RI12	intact:EBI-346653|uniprotkb:O95884|uniprotkb:Q7Z522|uniprotkb:Q8TBV1|uniprotkb:Q9UF25|uniprotkb:A8K105|uniprotkb:Q9UIC2|uniprotkb:B7Z3I5|ensembl:ENSP00000384720.2	intact:EBI-2849107|uniprotkb:O68717	psi-mi:evl_human(display_long)|uniprotkb:EVL(gene name)|psi-mi:EVL(display_short)|uniprotkb:RNB6(gene name synonym)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym)	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817788|imex:IM-26497-656	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057421.1|refseq:NP_001317150.1|panther:PTHR11202(orthology-group)|ensembl:ENSG00000196405.13(gene)|ensembl:ENST00000402714.6(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007015""(actin filament organization)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007411""(axon guidance)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010633""(negative regulation of epithelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:1900028""(negative regulation of ruffle assembly)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR038023|mint:Q9UI08|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-5663220"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:ZYA6pfvqC68sm/0egUg4hBif/Pc9606	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	intact-crc:8663E103676F1528|rigid:Xc1fkga7CcPABIkiXlUr1eK2dEY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:Q9RI07	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20817823	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:q9ri07_yerpe(display_long)|uniprotkb:Y0001(gene name)|psi-mi:Y0001(display_short)|uniprotkb:YPCD1.82c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817830|imex:IM-26497-468	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	mint:Q9RI07|interpro:IPR050900|interpro:IPR025948	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:HdBSwcWHdANPG9E/NcpIzrdCyzU632	intact-crc:2FDFEAA58A1F780A|rigid:B31gtnYIVW0yA/7H2llnP36QCwM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14764	uniprotkb:A0A2U2H1V0	intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977.5|ensembl:ENSP00000378760.1	intact:EBI-20817872|uniprotkb:A0A5P8YNF6|uniprotkb:A0A380PIB3|uniprotkb:A0A0H2W0F6|uniprotkb:Q74YL4|uniprotkb:A0A384KI65|uniprotkb:Q9RID3	psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym)	psi-mi:a0a2u2h1v0_yerpe(display_long)|uniprotkb:YMT1.42Ac(gene name)|psi-mi:YMT1.42Ac(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817905|imex:IM-26497-568	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364.19(gene)|ensembl:ENST00000357402.10(transcript)|ensembl:ENST00000395353.5(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0008283""(cell population proliferation)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031953""(negative regulation of protein autophosphorylation)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051028""(mRNA transport)|go:""GO:0061099""(negative regulation of protein tyrosine kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072376""(protein activation cascade)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695|refseq:NP_001280133.1|refseq:NP_001280134.1|panther:PTHR14165(orthology-group)"	"refseq:NP_395383.1|refseq:YP_093929.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:A0A2U2H1V0"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606	rogid:Y6BwO6B/qYza7nE/Xxp1jMICjfY632	intact-crc:FB3B407F9142A04C|rigid:OfwvVMR1TU0T4DH1IjB/kLQPLqg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BTE7	uniprotkb:A0A2U2H1V0	intact:EBI-3924013|uniprotkb:Q3ZTT2|ensembl:ENSP00000260247.5	intact:EBI-20817872|uniprotkb:A0A5P8YNF6|uniprotkb:A0A380PIB3|uniprotkb:A0A0H2W0F6|uniprotkb:Q74YL4|uniprotkb:A0A384KI65|uniprotkb:Q9RID3	psi-mi:dcnl5_human(display_long)|uniprotkb:DCUN1D5(gene name)|psi-mi:DCUN1D5(display_short)|uniprotkb:DCUN1 domain-containing protein 5(gene name synonym)|uniprotkb:Defective in cullin neddylation protein 1-like protein 5(gene name synonym)|uniprotkb:SCCRO5(gene name synonym)|uniprotkb:Squamous cell carcinoma-related oncogene 5(gene name synonym)	psi-mi:a0a2u2h1v0_yerpe(display_long)|uniprotkb:YMT1.42Ac(gene name)|psi-mi:YMT1.42Ac(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817899|imex:IM-26497-708	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115675.1|ensembl:ENSG00000137692.12(gene)|ensembl:ENST00000260247.10(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006974""(DNA damage response)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0032182""(ubiquitin-like protein binding)|go:""GO:0045116""(protein neddylation)|go:""GO:0097602""(cullin family protein binding)|go:""GO:2000434""(regulation of protein neddylation)|go:""GO:2000436""(positive regulation of protein neddylation)|interpro:IPR005176(Protein of unknown function DUF298)|interpro:IPR014764(Defective in cullin neddylation)|interpro:IPR042460|mint:Q9BTE7|reactome:R-HSA-8951664|panther:PTHR12281(orthology-group)"	"refseq:NP_395383.1|refseq:YP_093929.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:A0A2U2H1V0"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:EDYg7Tn8nZY4IPid4ZckCJ3e20M9606	rogid:Y6BwO6B/qYza7nE/Xxp1jMICjfY632	intact-crc:1B09CDCFA75B704B|rigid:c4kXgGwVBe1kbxDTj2PvxiJrAu8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P04233	uniprotkb:A0A2U2H1V0	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-20817872|uniprotkb:A0A5P8YNF6|uniprotkb:A0A380PIB3|uniprotkb:A0A0H2W0F6|uniprotkb:Q74YL4|uniprotkb:A0A384KI65|uniprotkb:Q9RID3	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:a0a2u2h1v0_yerpe(display_long)|uniprotkb:YMT1.42Ac(gene name)|psi-mi:YMT1.42Ac(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817893|imex:IM-26497-566	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"refseq:NP_395383.1|refseq:YP_093929.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:A0A2U2H1V0"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:Y6BwO6B/qYza7nE/Xxp1jMICjfY632	intact-crc:4D7D280B4764284D|rigid:aRQKHqJH35N3140y9va7OpJHdxw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:A0A3N4B9D7	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20818027|uniprotkb:A0A5P8YKV3|uniprotkb:Q0WJ72|uniprotkb:Q7CGD5	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:a0a3n4b9d7_yerpe(display_long)|uniprotkb:YPO0594(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818038|imex:IM-26497-664	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	mint:A0A3N4B9D7|interpro:IPR028274|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|refseq:YP_002345666.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:3oVm75D0MQU2owEK0RohZhgxDb4632	intact-crc:4995E420D4ED0A99|rigid:TrpDISZSXDQMHD9E76AqxRQBycU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P63167	uniprotkb:A0A5P8YMP8	intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577.6|ensembl:ENSP00000376296.2|ensembl:ENSP00000376297.2|ensembl:ENSP00000446614.1|ensembl:ENSP00000447907.1	intact:EBI-20817929|uniprotkb:Q65AE9|uniprotkb:A0A0H2VZS6|uniprotkb:A0A1U8QEN6|uniprotkb:O68783|uniprotkb:Q74YF8|uniprotkb:A0A384KAA6|uniprotkb:Q7ARB2	psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym)	psi-mi:a0a5p8ymp8_yerpe(display_long)|uniprotkb:YPMT1.75c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817948|imex:IM-26497-506	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|ensembl:ENSG00000088986.11(gene)|ensembl:ENST00000242577.11(transcript)|ensembl:ENST00000392508.2(transcript)|ensembl:ENST00000392509.6(transcript)|ensembl:ENST00000548342.5(transcript)|ensembl:ENST00000549989.1(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0016020""(membrane)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030286""(dynein complex)|go:""GO:0035721""(intraciliary retrograde transport)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042326""(negative regulation of phosphorylation)|go:""GO:0044458""(motile cilium assembly)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0060703""(deoxyribonuclease inhibitor activity)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0072686""(mitotic spindle)|go:""GO:0097542""(ciliary tip)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0110027""(negative regulation of DNA strand resection involved in replication fork processing)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGG|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|dip:DIP-33150N|panther:PTHR11886(orthology-group)"	"mint:A0A5P8YMP8|interpro:IPR051083|refseq:NP_395421.1|refseq:YP_094000.1|interpro:IPR000477(""RNA-directed DNA polymerase (reverse transcriptase)"")|interpro:IPR043502|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/28	rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606	rogid:+zbD2yE31CmjDqnFGaueJX7Q0Hg632	intact-crc:BC9CAE1E8F144484|rigid:rz1Qp9hnHCnrieHGiDYFD1idX9E	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBX5	uniprotkb:A0A2U2H1V0	intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008.4	intact:EBI-20817872|uniprotkb:A0A5P8YNF6|uniprotkb:A0A380PIB3|uniprotkb:A0A0H2W0F6|uniprotkb:Q74YL4|uniprotkb:A0A384KI65|uniprotkb:Q9RID3	psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name)	psi-mi:a0a2u2h1v0_yerpe(display_long)|uniprotkb:YMT1.42Ac(gene name)|psi-mi:YMT1.42Ac(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817917|imex:IM-26497-408	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000140092.16(gene)|ensembl:ENST00000342058.9(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0031012""(extracellular matrix)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046903""(secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000121""(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379|refseq:NP_006320.2|dip:DIP-44301N|efo:""Orphanet:280598""|efo:""Orphanet:90348""|efo:""Orphanet:90349""|panther:PTHR24034(orthology-group)"	"refseq:NP_395383.1|refseq:YP_093929.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:A0A2U2H1V0"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/26	rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606	rogid:Y6BwO6B/qYza7nE/Xxp1jMICjfY632	intact-crc:768574434682EE86|rigid:4xDulvK/LDt/+FdcS0XY4SusQSw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:A0A2U2H1V0	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20817872|uniprotkb:A0A5P8YNF6|uniprotkb:A0A380PIB3|uniprotkb:A0A0H2W0F6|uniprotkb:Q74YL4|uniprotkb:A0A384KI65|uniprotkb:Q9RID3	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:a0a2u2h1v0_yerpe(display_long)|uniprotkb:YMT1.42Ac(gene name)|psi-mi:YMT1.42Ac(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817923|imex:IM-26497-710	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"refseq:NP_395383.1|refseq:YP_093929.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:A0A2U2H1V0"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:Y6BwO6B/qYza7nE/Xxp1jMICjfY632	intact-crc:65618B3D660450F4|rigid:0JRDLoXv0/36DvnMzawD+e10S60	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96IT1	uniprotkb:A0A5P8YD56	intact:EBI-743906|uniprotkb:Q8TBS2|ensembl:ENSP00000294753.4|ensembl:ENSP00000507236.1|ensembl:ENSP00000517489.1|ensembl:ENSP00000517491.1	intact:EBI-20818090|uniprotkb:Q7CGQ8|uniprotkb:Q0WI80	psi-mi:zn496_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 17(gene name synonym)|uniprotkb:ZNF496(gene name)|psi-mi:ZNF496(display_short)|uniprotkb:ZKSCAN17(gene name synonym)	psi-mi:a0a5p8yd56_yerpe(display_long)|uniprotkb:YPO0962(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818105|imex:IM-26497-668	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_116141.1|refseq:XP_005273385.1|ensembl:ENSG00000162714.13(gene)|ensembl:ENSG00000291884.1(gene)|ensembl:ENST00000294753.8(transcript)|ensembl:ENST00000682384.1(transcript)|ensembl:ENST00000709063.1(transcript)|ensembl:ENST00000709067.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q96IT1|reactome:R-HSA-212436|panther:PTHR23226(orthology-group)"	mint:A0A5P8YD56|refseq:WP_002210005.1|interpro:IPR018769	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:rc+LTwSYrhXPLq9te9gIOqj2XnY9606	rogid:zbx8L1KjEhi8izH50nQjaxLF+Fk632	intact-crc:1442EAA17F34AB9B|rigid:LSJta83/puqT3xv5GzgSxglbJwI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q12846	uniprotkb:Q7CLC8	intact:EBI-744942|uniprotkb:Q15525|uniprotkb:Q6FHE8|uniprotkb:A8MXY0|ensembl:ENSP00000317714.3	intact:EBI-20817991|uniprotkb:A0A2U2H3P9|uniprotkb:A0A0H2W2D4|uniprotkb:Q74Y72|uniprotkb:A0A384L9W3|uniprotkb:A0A075EJ32	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:q7clc8_yerpe(display_long)|uniprotkb:glpF(gene name)|psi-mi:glpF(display_short)|uniprotkb:YPO0091(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818021|imex:IM-26497-716	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004595.2|refseq:NP_001259025.1|ensembl:ENSG00000103496.15(gene)|ensembl:ENST00000313843.8(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0000322""(storage vacuole)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005768""(endosome)|go:""GO:0005773""(vacuole)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006887""(exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0016230""(sphingomyelin phosphodiesterase activator activity)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0030027""(lamellipodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0032420""(stereocilium)|go:""GO:0032589""(neuron projection membrane)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0036477""(somatodendritic compartment)|go:""GO:0042581""(specific granule)|go:""GO:0043085""(positive regulation of catalytic activity)|go:""GO:0043197""(dendritic spine)|go:""GO:0043219""(lateral loop)|go:""GO:0043311""(positive regulation of eosinophil degranulation)|go:""GO:0045202""(synapse)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0048278""(vesicle docking)|go:""GO:0048284""(organelle fusion)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050921""(positive regulation of chemotaxis)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903575""(cornified envelope assembly)|go:""GO:2000010""(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR045242|mint:Q12846|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|panther:PTHR19957(orthology-group)"	"mint:Q7CLC8|interpro:IPR050363|interpro:IPR023271|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|refseq:YP_002345183.1|panther:PTHR43829(orthology-group)|refseq:WP_002208954.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015254""(glycerol channel activity)|go:""GO:0015793""(glycerol transmembrane transport)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	rogid:GvE0BhNEzuLdjFLI83rUxSmBe7Y632	intact-crc:B4AF2454AAF940DF|rigid:XOeW76ecOdjNNYgFpmuHl/6CnqQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P55268	uniprotkb:A0A3N4B5W9	intact:EBI-2529769|uniprotkb:Q16321|ensembl:ENSP00000307156.4|ensembl:ENSP00000388325.1	intact:EBI-20592344|uniprotkb:A0A0H2W7W4|uniprotkb:Q74QP5|uniprotkb:Q7CGM7|uniprotkb:A0A384KXH8	psi-mi:lamb2_human(display_long)|uniprotkb:Laminin-4 subunit beta(gene name synonym)|uniprotkb:Laminin-7 subunit beta(gene name synonym)|uniprotkb:Laminin-9 subunit beta(gene name synonym)|uniprotkb:Laminin-11 subunit beta(gene name synonym)|uniprotkb:Laminin-14 subunit beta(gene name synonym)|uniprotkb:Laminin-15 subunit beta(gene name synonym)|uniprotkb:S-laminin subunit beta(gene name synonym)|uniprotkb:LAMB2(gene name)|psi-mi:LAMB2(display_short)|uniprotkb:LAMS(gene name synonym)|uniprotkb:Laminin-3 subunit beta(gene name synonym)|uniprotkb:Laminin B1s chain(gene name synonym)	psi-mi:a0a3n4b5w9_yerpe(display_long)|uniprotkb:YPO1006(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818111|imex:IM-26497-574	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000172037.14(gene)|ensembl:ENST00000305544.9(transcript)|ensembl:ENST00000418109.5(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005608""(laminin-3 complex)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007155""(cell adhesion)|go:""GO:0007411""(axon guidance)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0007601""(visual perception)|go:""GO:0014002""(astrocyte development)|go:""GO:0014044""(Schwann cell development)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0043083""(synaptic cleft)|go:""GO:0043260""(laminin-11 complex)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0048677""(axon extension involved in regeneration)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072249""(metanephric podocyte development)|go:""GO:0072274""(metanephric glomerular basement membrane development)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:0110011""(regulation of basement membrane organization)|go:""GO:0150043""(structural constituent of synapse-associated extracellular matrix)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|interpro:IPR050440|mint:P55268|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|refseq:NP_002283.3|refseq:XP_005265184.1|dip:DIP-42106N|efo:""Orphanet:2670""|efo:""Orphanet:98915""|panther:PTHR24035(orthology-group)"	"interpro:IPR051071|go:""GO:0005576""(extracellular region)|refseq:WP_002214025.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR001611(Leucine-rich repeat)|panther:PTHR47114(orthology-group)|refseq:YP_002346051.1|mint:A0A3N4B5W9"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:LY1lt2hyTcFN+x4GtvfzufChDF89606	rogid:J2v9cU/a7BimPcEvtvodoAcWK2g632	intact-crc:CDAB2963CFB3AA84|rigid:xUlL3zXpgWImR+EwGSgioV3Bl/I	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75094	uniprotkb:A0A3N4B9D7	intact:EBI-2622593|uniprotkb:Q9UFH5|uniprotkb:O95804|uniprotkb:A6H8U9|ensembl:ENSP00000430333.2|uniprotkb:J3KNP3	intact:EBI-20818027|uniprotkb:A0A5P8YKV3|uniprotkb:Q0WJ72|uniprotkb:Q7CGD5	psi-mi:slit3_human(display_long)|uniprotkb:KIAA0814(gene name synonym)|uniprotkb:MEGF5(gene name synonym)|uniprotkb:SLIL2(gene name synonym)|uniprotkb:Multiple epidermal growth factor-like domains protein 5(gene name synonym)|uniprotkb:UNQ691/PRO1336(orf name)|uniprotkb:SLIT3(gene name)|psi-mi:SLIT3(display_short)	psi-mi:a0a3n4b9d7_yerpe(display_long)|uniprotkb:YPO0594(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818044|imex:IM-26497-416	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003053.1|refseq:NP_001258875.1|ensembl:ENSG00000184347.16(gene)|ensembl:ENST00000519560.6(transcript)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005739""(mitochondrion)|go:""GO:0007411""(axon guidance)|go:""GO:0008201""(heparin binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0048495""(Roundabout binding)|go:""GO:0048846""(axon extension involved in axon guidance)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051414""(response to cortisol)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0061364""(apoptotic process involved in luteolysis)|go:""GO:0070100""(negative regulation of chemokine-mediated signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|interpro:IPR051355|mint:O75094|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428542|panther:PTHR45836(orthology-group)"	mint:A0A3N4B9D7|interpro:IPR028274|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|refseq:YP_002345666.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:Qazwnc23w/tZ8NsF8G3ZLSEF1SE9606	rogid:3oVm75D0MQU2owEK0RohZhgxDb4632	intact-crc:ACA0CBAE5C7FD48E|rigid:f9SZk6c5qrm60Xr3WF7JTdmwT14	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q12805	uniprotkb:A0A3N4B9D7	intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|uniprotkb:B4DW75|ensembl:ENSP00000347596.3|ensembl:ENSP00000378058.2	intact:EBI-20818027|uniprotkb:A0A5P8YKV3|uniprotkb:Q0WJ72|uniprotkb:Q7CGD5	psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym)	psi-mi:a0a3n4b9d7_yerpe(display_long)|uniprotkb:YPO0594(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818050|imex:IM-26497-470	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24039(orthology-group)|ensembl:ENSG00000115380.20(gene)|ensembl:ENST00000355426.8(transcript)|ensembl:ENST00000394555.6(transcript)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007601""(visual perception)|go:""GO:0008083""(growth factor activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0043010""(camera-type eye development)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1|efo:""Orphanet:75376""|efo:""Orphanet:98977"""	mint:A0A3N4B9D7|interpro:IPR028274|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|refseq:YP_002345666.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606	rogid:3oVm75D0MQU2owEK0RohZhgxDb4632	intact-crc:C540038ABD2ADA12|rigid:fDNxJbs6E9gcJM20Dt4g1JyltUs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P12814	uniprotkb:A0A384L505	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403.6	intact:EBI-20818062|uniprotkb:A0A3G5LB56|uniprotkb:Q0WIY5|uniprotkb:A0A2S9PLV5|uniprotkb:A0A5P8YMC7	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:a0a384l505_yerpe(display_long)|uniprotkb:YPO0687(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818072|imex:IM-26497-508	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:140957""|ensembl:ENSG00000072110.17(gene)|ensembl:ENST00000193403.11(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007015""(actin filament organization)|go:""GO:0017166""(vinculin binding)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030220""(platelet formation)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031143""(pseudopodium)|go:""GO:0036344""(platelet morphogenesis)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0042995""(cell projection)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051639""(actin filament network formation)|go:""GO:0055001""(muscle cell development)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099186""(structural constituent of postsynapse)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034|refseq:NP_001093.1|refseq:NP_001123476.1|refseq:NP_001123477.1|dip:DIP-33184N|panther:PTHR11915(orthology-group)"	mint:A0A384L505|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:YP_002345753.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	rogid:HYXNRCad/zff+hmqUZxQEEjWdPU632	intact-crc:2B1496FD16C5E668|rigid:R8tSmMfDehbubUXu+nNozmye5w0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P06753	uniprotkb:A0A5P8YD56	intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|uniprotkb:Q5VU66|uniprotkb:Q5VU72|ensembl:ENSP00000498577.1|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3|intact:EBI-11063811	intact:EBI-20818090|uniprotkb:Q7CGQ8|uniprotkb:Q0WI80	psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym)	psi-mi:a0a5p8yd56_yerpe(display_long)|uniprotkb:YPO0962(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818099|imex:IM-26497-718	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:171433""|efo:""Orphanet:171439""|efo:""Orphanet:171881""|efo:""Orphanet:178342""|efo:""Orphanet:2020""|efo:""Orphanet:476406""|ensembl:ENSG00000143549.22(gene)|ensembl:ENST00000651641.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005862""(muscle thin filament tropomyosin)|go:""GO:0005884""(actin filament)|go:""GO:0006936""(muscle contraction)|go:""GO:0007015""(actin filament organization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|reactome:R-HSA-9725370|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_001036818.1|refseq:NP_001265118.1|refseq:NP_001265120.1|refseq:NP_689476.2|refseq:NP_705935.1|panther:PTHR19269(orthology-group)"	mint:A0A5P8YD56|refseq:WP_002210005.1|interpro:IPR018769	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606	rogid:zbx8L1KjEhi8izH50nQjaxLF+Fk632	intact-crc:A9D1495115B4A52D|rigid:7KY2+dtoCIiQ0EplDdS605+hu4c	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P17980	uniprotkb:A0A3N4B9D7	intact:EBI-359720|uniprotkb:Q3B757|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1|ensembl:ENSP00000298852.3|ensembl:ENSP00000481029.1	intact:EBI-20818027|uniprotkb:A0A5P8YKV3|uniprotkb:Q0WJ72|uniprotkb:Q7CGD5	psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym)	psi-mi:a0a3n4b9d7_yerpe(display_long)|uniprotkb:YPO0594(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818056|imex:IM-26497-666	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002795.2|ensembl:ENSG00000165916.9(gene)|ensembl:ENST00000298852.8(transcript)|ensembl:ENST00000619920.4(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0000932""(P-body)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043921""(modulation by host of viral transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-27555N|panther:PTHR23073(orthology-group)"	mint:A0A3N4B9D7|interpro:IPR028274|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|refseq:YP_002345666.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606	rogid:3oVm75D0MQU2owEK0RohZhgxDb4632	intact-crc:E03F05AA2A3A66C1|rigid:V7mPQ9NMXagraFU7XjGru717yZc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O15162	uniprotkb:A0A5P8YMP8	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	intact:EBI-20817929|uniprotkb:Q65AE9|uniprotkb:A0A0H2VZS6|uniprotkb:A0A1U8QEN6|uniprotkb:O68783|uniprotkb:Q74YF8|uniprotkb:A0A384KAA6|uniprotkb:Q7ARB2	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	psi-mi:a0a5p8ymp8_yerpe(display_long)|uniprotkb:YPMT1.75c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817960|imex:IM-26497-412	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	"mint:A0A5P8YMP8|interpro:IPR051083|refseq:NP_395421.1|refseq:YP_094000.1|interpro:IPR000477(""RNA-directed DNA polymerase (reverse transcriptase)"")|interpro:IPR043502|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:+zbD2yE31CmjDqnFGaueJX7Q0Hg632	intact-crc:E0C1A063598B1DF3|rigid:hZcEDsjb+QXaUru1GEWvLlxuFkw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:A0A384L505	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20818062|uniprotkb:A0A3G5LB56|uniprotkb:Q0WIY5|uniprotkb:A0A2S9PLV5|uniprotkb:A0A5P8YMC7	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:a0a384l505_yerpe(display_long)|uniprotkb:YPO0687(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818078|imex:IM-26497-472	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	mint:A0A384L505|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:YP_002345753.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:HYXNRCad/zff+hmqUZxQEEjWdPU632	intact-crc:714C7BA3B54586FB|rigid:KihseyzvXz88z7DSivueyJ/chzc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:A0A2U2H1V0	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20817872|uniprotkb:A0A5P8YNF6|uniprotkb:A0A380PIB3|uniprotkb:A0A0H2W0F6|uniprotkb:Q74YL4|uniprotkb:A0A384KI65|uniprotkb:Q9RID3	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:a0a2u2h1v0_yerpe(display_long)|uniprotkb:YMT1.42Ac(gene name)|psi-mi:YMT1.42Ac(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817911|imex:IM-26497-570	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	"refseq:NP_395383.1|refseq:YP_093929.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:A0A2U2H1V0"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:Y6BwO6B/qYza7nE/Xxp1jMICjfY632	intact-crc:7567D90A54C92F9C|rigid:bq5s1WaE1LXCcMBa7TU5Z8hkjmY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:A0A5P8YMP8	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20817929|uniprotkb:Q65AE9|uniprotkb:A0A0H2VZS6|uniprotkb:A0A1U8QEN6|uniprotkb:O68783|uniprotkb:Q74YF8|uniprotkb:A0A384KAA6|uniprotkb:Q7ARB2	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:a0a5p8ymp8_yerpe(display_long)|uniprotkb:YPMT1.75c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817954|imex:IM-26497-410	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	"mint:A0A5P8YMP8|interpro:IPR051083|refseq:NP_395421.1|refseq:YP_094000.1|interpro:IPR000477(""RNA-directed DNA polymerase (reverse transcriptase)"")|interpro:IPR043502|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:+zbD2yE31CmjDqnFGaueJX7Q0Hg632	intact-crc:5FF1D7F7FEA68853|rigid:4ZO7aJmHTXX/z3htkcrrrK/66zk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:Q9RIC2	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20817966|uniprotkb:A0A3G5LAG2|uniprotkb:A0A2S9PC24|uniprotkb:Q7BTT3|uniprotkb:A0A384LEY1|uniprotkb:A0A5P8YM61	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:q9ric2_yerpe(display_long)|uniprotkb:YPMT1.76A(gene name)|psi-mi:YPMT1.76A(display_short)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817979|imex:IM-26497-572	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	refseq:NP_395423.1|refseq:NP_857703.3|mint:Q9RIC2	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:AYcKfmXasgfGudSJnqoveyUnb4k632	intact-crc:88D9CDCF930FAFEB|rigid:JzOijl/FE0FfBZdlHrJmxgtYd0M	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:A0A384L505	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20818062|uniprotkb:A0A3G5LB56|uniprotkb:Q0WIY5|uniprotkb:A0A2S9PLV5|uniprotkb:A0A5P8YMC7	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:a0a384l505_yerpe(display_long)|uniprotkb:YPO0687(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818084|imex:IM-26497-610	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	mint:A0A384L505|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:YP_002345753.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:HYXNRCad/zff+hmqUZxQEEjWdPU632	intact-crc:886183CA46242D73|rigid:vGTj0/l3Z7iH9GmYla+sVqOt1SE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y228	uniprotkb:Q7CLC8	intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991.1|ensembl:ENSP00000355992.3	intact:EBI-20817991|uniprotkb:A0A2U2H3P9|uniprotkb:A0A0H2W2D4|uniprotkb:Q74Y72|uniprotkb:A0A384L9W3|uniprotkb:A0A075EJ32	psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym)	psi-mi:q7clc8_yerpe(display_long)|uniprotkb:glpF(gene name)|psi-mi:glpF(display_short)|uniprotkb:YPO0091(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818015|imex:IM-26497-414	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790.15(gene)|ensembl:ENST00000367024.5(transcript)|ensembl:ENST00000367025.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0060090""(molecular adaptor activity)|interpro:IPR051176|mint:Q9Y228|panther:PTHR15715(orthology-group)"	"mint:Q7CLC8|interpro:IPR050363|interpro:IPR023271|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|refseq:YP_002345183.1|panther:PTHR43829(orthology-group)|refseq:WP_002208954.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015254""(glycerol channel activity)|go:""GO:0015793""(glycerol transmembrane transport)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606	rogid:GvE0BhNEzuLdjFLI83rUxSmBe7Y632	intact-crc:D42E05564A3DC4E0|rigid:ZvDv6ERPBp1QLPvbOlVr+sgFAKA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P55268	uniprotkb:P26926	intact:EBI-2529769|uniprotkb:Q16321|ensembl:ENSP00000307156.4|ensembl:ENSP00000388325.1	intact:EBI-1036581|uniprotkb:O68774|uniprotkb:Q9RIB9	psi-mi:lamb2_human(display_long)|uniprotkb:Laminin-4 subunit beta(gene name synonym)|uniprotkb:Laminin-7 subunit beta(gene name synonym)|uniprotkb:Laminin-9 subunit beta(gene name synonym)|uniprotkb:Laminin-11 subunit beta(gene name synonym)|uniprotkb:Laminin-14 subunit beta(gene name synonym)|uniprotkb:Laminin-15 subunit beta(gene name synonym)|uniprotkb:S-laminin subunit beta(gene name synonym)|uniprotkb:LAMB2(gene name)|psi-mi:LAMB2(display_short)|uniprotkb:LAMS(gene name synonym)|uniprotkb:Laminin-3 subunit beta(gene name synonym)|uniprotkb:Laminin B1s chain(gene name synonym)	psi-mi:caf1m_yerpe(display_long)|uniprotkb:caf1M(gene name)|psi-mi:caf1M(display_short)|uniprotkb:YPMT1.82(locus name)|uniprotkb:YP_pMT084(locus name)|uniprotkb:Capsule protein fraction 1(gene name synonym)|uniprotkb:Y1098(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20817985|imex:IM-26497-712	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000172037.14(gene)|ensembl:ENST00000305544.9(transcript)|ensembl:ENST00000418109.5(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005608""(laminin-3 complex)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007155""(cell adhesion)|go:""GO:0007411""(axon guidance)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0007601""(visual perception)|go:""GO:0014002""(astrocyte development)|go:""GO:0014044""(Schwann cell development)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0043083""(synaptic cleft)|go:""GO:0043260""(laminin-11 complex)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0048677""(axon extension involved in regeneration)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072249""(metanephric podocyte development)|go:""GO:0072274""(metanephric glomerular basement membrane development)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:0110011""(regulation of basement membrane organization)|go:""GO:0150043""(structural constituent of synapse-associated extracellular matrix)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|interpro:IPR050440|mint:P55268|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|refseq:NP_002283.3|refseq:XP_005265184.1|dip:DIP-42106N|efo:""Orphanet:2670""|efo:""Orphanet:98915""|panther:PTHR24035(orthology-group)"	"refseq:NP_395428.1|refseq:NP_857694.1|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0071555""(cell wall organization)|interpro:IPR001829(Pili assembly chaperone, bacterial)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016147(Pili assembly chaperone, N-terminal, bacterial)|interpro:IPR016148(Pili assembly chaperone, C-terminal, bacterial)|interpro:IPR018046|interpro:IPR036316|interpro:IPR050643|rcsb pdb:1P5U|rcsb pdb:1P5V|rcsb pdb:1Z9S|rcsb pdb:2OS7|rcsb pdb:3DOS|rcsb pdb:3DPB|rcsb pdb:3DSN|rcsb pdb:4AY0|rcsb pdb:4AYF|rcsb pdb:4AZ8|rcsb pdb:4B0M|refseq:WP_002211762.1|dip:DIP-35244N|mint:P26926|panther:PTHR30251(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:LY1lt2hyTcFN+x4GtvfzufChDF89606	rogid:/NMyqMayfxLXO+4MVg01FP+f8j4632	intact-crc:32BDC746ABF06169|rigid:R0t8U/BvVLZBm1HRumaXWap8Ef8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9P2W9	uniprotkb:Q7CLC8	intact:EBI-725334|uniprotkb:Q596L3|uniprotkb:Q5TZP5|ensembl:ENSP00000305810.2	intact:EBI-20817991|uniprotkb:A0A2U2H3P9|uniprotkb:A0A0H2W2D4|uniprotkb:Q74Y72|uniprotkb:A0A384L9W3|uniprotkb:A0A075EJ32	psi-mi:stx18_human(display_long)|uniprotkb:Cell growth-inhibiting gene 9 protein(gene name synonym)|uniprotkb:STX18(gene name)|psi-mi:STX18(display_short)|uniprotkb:GIG9(orf name)	psi-mi:q7clc8_yerpe(display_long)|uniprotkb:glpF(gene name)|psi-mi:glpF(display_short)|uniprotkb:YPO0091(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818009|imex:IM-26497-714	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_058626.1|refseq:NP_001333211.1|refseq:NP_001333210.1|refseq:NP_001333229.1|dip:DIP-37617N|ensembl:ENSG00000168818.10(gene)|ensembl:ENST00000306200.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031201""(SNARE complex)|go:""GO:0090158""(endoplasmic reticulum membrane organization)|go:""GO:1902117""(positive regulation of organelle assembly)|go:""GO:1902953""(positive regulation of ER to Golgi vesicle-mediated transport)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR019529|mint:Q9P2W9|reactome:R-HSA-6811434|panther:PTHR15959(orthology-group)"	"mint:Q7CLC8|interpro:IPR050363|interpro:IPR023271|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|refseq:YP_002345183.1|panther:PTHR43829(orthology-group)|refseq:WP_002208954.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015254""(glycerol channel activity)|go:""GO:0015793""(glycerol transmembrane transport)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/05	rogid:QpvkckDM1D5Jaty6AmK3vEwRZts9606	rogid:GvE0BhNEzuLdjFLI83rUxSmBe7Y632	intact-crc:9AB7715211B55539|rigid:bqaSGaec3l+jlLS1GWCyH1kErMs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NSC5	uniprotkb:A0A3N4B5W9	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|ensembl:ENSP00000376162.2|ensembl:ENSP00000439937.1|ensembl:ENSP00000446026.1|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-20592344|uniprotkb:A0A0H2W7W4|uniprotkb:Q74QP5|uniprotkb:Q7CGM7|uniprotkb:A0A384KXH8	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:a0a3n4b5w9_yerpe(display_long)|uniprotkb:YPO1006(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818129|imex:IM-26497-510	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128.19(gene)|ensembl:ENST00000392351.8(transcript)|ensembl:ENST00000539827.5(transcript)|ensembl:ENST00000542541.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0007216""(G protein-coupled glutamate receptor signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030425""(dendrite)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0035256""(G protein-coupled glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045178""(basal part of cell)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2001256""(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|interpro:IPR045027|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|panther:PTHR10918(orthology-group)"	"interpro:IPR051071|go:""GO:0005576""(extracellular region)|refseq:WP_002214025.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR001611(Leucine-rich repeat)|panther:PTHR47114(orthology-group)|refseq:YP_002346051.1|mint:A0A3N4B5W9"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:J2v9cU/a7BimPcEvtvodoAcWK2g632	intact-crc:8EECDCE4A2B29628|rigid:LSThQfpaW/DDN9FrSFwvXmoCNbE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A9UHW6	uniprotkb:A0A0H2W443	intact:EBI-373498|uniprotkb:Q8N4Q5|intact:EBI-946774|uniprotkb:B4DUM7|uniprotkb:Q9HBL5|ensembl:ENSP00000321625.8|ensembl:ENSP00000484245.1	intact:EBI-20818144|uniprotkb:A0A384KVQ9|uniprotkb:Q74W32|uniprotkb:Q7CH33|uniprotkb:Q0WHV6	psi-mi:mi4gd_human(display_long)|uniprotkb:SLIP1(gene name synonym)|uniprotkb:SLBP-interacting protein 1(gene name synonym)|uniprotkb:MIF4GD(gene name)|psi-mi:MIF4GD(display_short)	psi-mi:a0a0h2w443_yerpe(display_long)|uniprotkb:YPO1088(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818165|imex:IM-26497-512	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229427.1|refseq:NP_001229429.1|refseq:NP_001229430.1|refseq:NP_065730.2|refseq:XP_011523354.1|refseq:XP_005257589.1|refseq:XP_005257590.1|ensembl:ENSG00000125457.15(gene)|ensembl:ENST00000325102.13(transcript)|ensembl:ENST00000618645.5(transcript)|go:""GO:0002191""(cap-dependent translational initiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0008494""(translation activator activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0062073""(histone mRNA stem-loop binding complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR051367|mint:A9UHW6|refseq:XP_016880382.1|refseq:XP_016880383.1|refseq:XP_005257587.1|panther:PTHR23254(orthology-group)"	"mint:A0A0H2W443|interpro:IPR014057(Addiction module antidote protein, HI1420)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|refseq:YP_002346132.1|go:""GO:0003677""(DNA binding)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:fVJrdaWCxDp4EBdc1QyA0lECSGE9606	rogid:SMD/VqWJoCGU3hcPKWAbpZhhEHU632	intact-crc:2F88C93BFFC89CB8|rigid:HPwoLF5SiAQEG3bBNIpt8SwxscM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P01903	uniprotkb:A0A3N4B5W9	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608.2|ensembl:ENSP00000372746.2|ensembl:ENSP00000378786.2|ensembl:ENSP00000402951.2|ensembl:ENSP00000404533.2|ensembl:ENSP00000405295.2|ensembl:ENSP00000410443.2|ensembl:ENSP00000479287.1	intact:EBI-20592344|uniprotkb:A0A0H2W7W4|uniprotkb:Q74QP5|uniprotkb:Q7CGM7|uniprotkb:A0A384KXH8	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	psi-mi:a0a3n4b5w9_yerpe(display_long)|uniprotkb:YPO1006(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818117|imex:IM-26497-762	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-6063N|efo:""Orphanet:505""|ensembl:ENSG00000204287.14(gene)|ensembl:ENSG00000206308.11(gene)|ensembl:ENSG00000226260.9(gene)|ensembl:ENSG00000227993.9(gene)|ensembl:ENSG00000228987.9(gene)|ensembl:ENSG00000230726.9(gene)|ensembl:ENSG00000234794.9(gene)|ensembl:ENSG00000277263.1(gene)|ensembl:ENST00000383127.6(transcript)|ensembl:ENST00000383259.6(transcript)|ensembl:ENST00000395388.7(transcript)|ensembl:ENST00000411524.6(transcript)|ensembl:ENST00000414698.6(transcript)|ensembl:ENST00000416883.6(transcript)|ensembl:ENST00000442960.6(transcript)|ensembl:ENST00000613328.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050890""(cognition)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01903|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:1ZGL|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:7N19|rcsb pdb:7NZE|rcsb pdb:7O00|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8CMB|rcsb pdb:8CMC|rcsb pdb:8CMD|rcsb pdb:8CME|rcsb pdb:8CMF|rcsb pdb:8CMG|rcsb pdb:8CMH|rcsb pdb:8CMI|rcsb pdb:8EUQ|rcsb pdb:8PJE|rcsb pdb:8PJF|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:9B7B|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_061984.2|panther:PTHR19944(orthology-group)"	"interpro:IPR051071|go:""GO:0005576""(extracellular region)|refseq:WP_002214025.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR001611(Leucine-rich repeat)|panther:PTHR47114(orthology-group)|refseq:YP_002346051.1|mint:A0A3N4B5W9"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	rogid:J2v9cU/a7BimPcEvtvodoAcWK2g632	intact-crc:E585BC2DD21644CC|rigid:7L8ha5xWuT3kTl4qTzVazSI5DMI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8WV41	uniprotkb:A0A0H2W443	intact:EBI-2481535|uniprotkb:B1NM17|ensembl:ENSP00000311427.6	intact:EBI-20818144|uniprotkb:A0A384KVQ9|uniprotkb:Q74W32|uniprotkb:Q7CH33|uniprotkb:Q0WHV6	psi-mi:snx33_human(display_long)|uniprotkb:SNX33(gene name)|psi-mi:SNX33(display_short)|uniprotkb:SH3PX3(gene name synonym)|uniprotkb:SH3PXD3C(gene name synonym)|uniprotkb:SNX30(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3(gene name synonym)	psi-mi:a0a0h2w443_yerpe(display_long)|uniprotkb:YPO1088(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818159|imex:IM-26497-474	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_695003.1|refseq:NP_001305075.1|ensembl:ENSG00000173548.9(gene)|ensembl:ENST00000308527.6(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0007032""(endosome organization)|go:""GO:0016020""(membrane)|go:""GO:0016197""(endosomal transport)|go:""GO:0017038""(protein import)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0042802""(identical protein binding)|go:""GO:0044351""(macropinocytosis)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0051044""(positive regulation of membrane protein ectodomain proteolysis)|go:""GO:0097320""(plasma membrane tubulation)|go:""GO:2000009""(negative regulation of protein localization to cell surface)|go:""GO:2000010""(positive regulation of protein localization to cell surface)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR036028|interpro:IPR036871|interpro:IPR037427|mint:Q8WV41|rcsb pdb:4AKV|panther:PTHR45827(orthology-group)"	"mint:A0A0H2W443|interpro:IPR014057(Addiction module antidote protein, HI1420)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|refseq:YP_002346132.1|go:""GO:0003677""(DNA binding)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:rhvspe+J40o9M1MJtpUIyeQFLRs9606	rogid:SMD/VqWJoCGU3hcPKWAbpZhhEHU632	intact-crc:3044762F9EFC1CCB|rigid:leIpgQnOyVsaHpncU+ByiUoBpp0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5VU43	uniprotkb:A0A5P8YD14	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360.3|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	intact:EBI-20818135|uniprotkb:A0A2U2H3R1|uniprotkb:Q74RY4|uniprotkb:Q7CGZ9|uniprotkb:A0A0H2W6L5|uniprotkb:A0A384KZ06	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:a0a5p8yd14_yerpe(display_long)|uniprotkb:YPO1017(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818138|imex:IM-26497-418	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|ensembl:ENSG00000178104.22(gene)|ensembl:ENST00000369354.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0007098""(centrosome cycle)|go:""GO:0019899""(enzyme binding)|go:""GO:0030016""(myofibril)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|interpro:IPR052593|mint:Q5VU43|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|panther:PTHR46501(orthology-group)"	"mint:A0A5P8YD14|interpro:IPR022204|refseq:WP_002228047.1|refseq:YP_002346061.1|interpro:IPR012902(Prepilin-type cleavage/methylation, N-terminal)|go:""GO:0016020""(membrane)"	-	-	caution:This sequence has been withdrawn from Uniprot.	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	rogid:80c2lMMJcsNRKeOU36iLY3LEic4632	intact-crc:66CCE6E4C7DC1E03|rigid:LYGaW3clfoaRaymqYLce0DJTrZ0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:A0A5P8YDN2	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20818191|uniprotkb:A0A3G5L2M3|uniprotkb:Q0WHF3|uniprotkb:A0A2S9PL27|uniprotkb:A0A384KKI1|uniprotkb:A0A6B3T5S2	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:a0a5p8ydn2_yerpe(display_long)|uniprotkb:YPO1255(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818200|imex:IM-26497-476	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	mint:A0A5P8YDN2|refseq:WP_002208841.1|refseq:YP_002346285.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:YutlDnuv1N3lfXtKC/A0XETr/k0632	intact-crc:DB93D4341E406952|rigid:6oxaP7zLKm1BFQc6kLQpn/ZG/+8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:A0A6M0NPF9	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20818171|uniprotkb:A0A3G5L8D9|uniprotkb:Q74W41|uniprotkb:A0A2S9PB81|uniprotkb:A0A384LPY7|uniprotkb:A0A6B3T911	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:a0a6m0npf9_yerpe(display_long)|uniprotkb:YPO1095(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818179|imex:IM-26497-670	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	mint:A0A6M0NPF9|refseq:WP_002215946.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:nrwho6zJJ1+rbE169axnK77H68I632	intact-crc:24DCF16F350084C1|rigid:kD8gnZvdGuW1mO4hHkDXliMWf/s	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05141	uniprotkb:A0A3N4B5W9	intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671.4	intact:EBI-20592344|uniprotkb:A0A0H2W7W4|uniprotkb:Q74QP5|uniprotkb:Q7CGM7|uniprotkb:A0A384KXH8	psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym)	psi-mi:a0a3n4b5w9_yerpe(display_long)|uniprotkb:YPO1006(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818123|imex:IM-26497-720	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001143.2|ensembl:ENSG00000005022.6(gene)|ensembl:ENST00000317881.9(transcript)|go:""GO:0000295""(adenine nucleotide transmembrane transporter activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005471""(""ATP:ADP antiporter activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005757""(mitochondrial permeability transition pore complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0007059""(chromosome segregation)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0015078""(proton transmembrane transporter activity)|go:""GO:0015207""(adenine transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0017077""(oxidative phosphorylation uncoupler activity)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0046902""(regulation of mitochondrial membrane permeability)|go:""GO:0051503""(adenine nucleotide transport)|go:""GO:0071817""(MMXD complex)|go:""GO:0140021""(mitochondrial ADP transmembrane transport)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1901526""(positive regulation of mitophagy)|go:""GO:1990544""(mitochondrial ATP transmembrane transport)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990845""(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|reactome:R-HSA-180897|reactome:R-HSA-83936|reactome:R-HSA-9837999|dip:DIP-33873N|panther:PTHR45635(orthology-group)"	"interpro:IPR051071|go:""GO:0005576""(extracellular region)|refseq:WP_002214025.1|interpro:IPR032675|interpro:IPR032674|interpro:IPR001611(Leucine-rich repeat)|panther:PTHR47114(orthology-group)|refseq:YP_002346051.1|mint:A0A3N4B5W9"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/28	rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606	rogid:J2v9cU/a7BimPcEvtvodoAcWK2g632	intact-crc:E87414F6C3A51DB3|rigid:ArF4X5HNXIDdvBXg5QUR66cB6LY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P46379	uniprotkb:A0A6M0NPF9	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-20818171|uniprotkb:A0A3G5L8D9|uniprotkb:Q74W41|uniprotkb:A0A2S9PB81|uniprotkb:A0A384LPY7|uniprotkb:A0A6B3T911	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:a0a6m0npf9_yerpe(display_long)|uniprotkb:YPO1095(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818185|imex:IM-26497-728	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	mint:A0A6M0NPF9|refseq:WP_002215946.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:nrwho6zJJ1+rbE169axnK77H68I632	intact-crc:9352EB22264AC929|rigid:H2eNkAByvrDbchgPLFZUmSBMxmA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:Q8ZG77	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20592302|uniprotkb:Q0WGY2|uniprotkb:Q74VI2|uniprotkb:Q8D056	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:ompa_yerpe(display_long)|uniprotkb:Outer membrane porin A(gene name synonym)|uniprotkb:y2735(locus name)|uniprotkb:ompA(gene name)|psi-mi:ompA(display_short)|uniprotkb:ompA1(gene name synonym)|uniprotkb:YPO1435(locus name)|uniprotkb:YP_1326(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818235|imex:IM-26497-612	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"interpro:IPR050330|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|refseq:WP_002213066.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR002368(Outer membrane protein, OmpA)|panther:PTHR30128(orthology-group)|refseq:YP_002346456.1|mint:Q8ZG77"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:q86tZqya2906j6c/oL0NQ6Kmy84632	intact-crc:CB1DF364F2F822CA|rigid:Z5mcK2u9eYA+CyPvKp842Aow+tQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H0F6	uniprotkb:Q8ZG77	intact:EBI-3942966|uniprotkb:D3DWL3|uniprotkb:Q8IXF5|uniprotkb:Q8IXF6|uniprotkb:A6NEG3|uniprotkb:Q8TB25|uniprotkb:Q9BUE4|uniprotkb:Q8N2E7|uniprotkb:C0L3L2|ensembl:ENSP00000381698.2	intact:EBI-20592302|uniprotkb:Q0WGY2|uniprotkb:Q74VI2|uniprotkb:Q8D056	psi-mi:shrpn_human(display_long)|uniprotkb:SHARPIN(gene name)|psi-mi:SHARPIN(display_short)|uniprotkb:SIPL1(gene name synonym)|uniprotkb:Shank-associated RH domain-interacting protein(gene name synonym)|uniprotkb:Shank-interacting protein-like 1(gene name synonym)|uniprotkb:PSEC0216(orf name)	psi-mi:ompa_yerpe(display_long)|uniprotkb:Outer membrane porin A(gene name synonym)|uniprotkb:y2735(locus name)|uniprotkb:ompA(gene name)|psi-mi:ompA(display_short)|uniprotkb:ompA1(gene name synonym)|uniprotkb:YPO1435(locus name)|uniprotkb:YP_1326(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818247|imex:IM-26497-766	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_112236.3|refseq:XP_016869377.1|dip:DIP-57842N|ensembl:ENSG00000179526.17(gene)|ensembl:ENST00000398712.7(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0030262""(apoptotic nuclear changes)|go:""GO:0030425""(dendrite)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031424""(keratinization)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0071797""(LUBAC complex)|go:""GO:0097039""(protein linear polyubiquitination)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000348""(regulation of CD40 signaling pathway)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR031912|interpro:IPR036443|interpro:IPR051628|mint:Q9H0F6|rcsb pdb:4EMO|rcsb pdb:5X0W|rcsb pdb:8K6P|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-6794361"	"interpro:IPR050330|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|refseq:WP_002213066.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR002368(Outer membrane protein, OmpA)|panther:PTHR30128(orthology-group)|refseq:YP_002346456.1|mint:Q8ZG77"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:+RGl3JO1zsGCdaInDn20yhNZs0E9606	rogid:q86tZqya2906j6c/oL0NQ6Kmy84632	intact-crc:D676D42BC9AB7CF3|rigid:aKCVllSZWO01wlid53zXUBixSkU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P54259	uniprotkb:Q8ZG77	intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076.3|ensembl:ENSP00000379915.2	intact:EBI-20592302|uniprotkb:Q0WGY2|uniprotkb:Q74VI2|uniprotkb:Q8D056	psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym)	psi-mi:ompa_yerpe(display_long)|uniprotkb:Outer membrane porin A(gene name synonym)|uniprotkb:y2735(locus name)|uniprotkb:ompA(gene name)|psi-mi:ompA(display_short)|uniprotkb:ompA1(gene name synonym)|uniprotkb:YPO1435(locus name)|uniprotkb:YP_1326(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818229|imex:IM-26497-730	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111676.15(gene)|ensembl:ENST00000356654.8(transcript)|ensembl:ENST00000396684.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001906""(cell killing)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008584""(male gonad development)|go:""GO:0009791""(post-embryonic development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0032094""(response to food)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0070161""(anchoring junction)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724|refseq:NP_001007027.1|refseq:NP_001931.2|dip:DIP-29423N|efo:""Orphanet:101""|panther:PTHR13859(orthology-group)"	"interpro:IPR050330|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|refseq:WP_002213066.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR002368(Outer membrane protein, OmpA)|panther:PTHR30128(orthology-group)|refseq:YP_002346456.1|mint:Q8ZG77"	-	crc64:B47603486C672637	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/01/27	rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606	rogid:q86tZqya2906j6c/oL0NQ6Kmy84632	intact-crc:1BE56011B026BFCA|rigid:i6+nCl7Ccjp9Gi5bhSyt6NFF6FU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O14545	uniprotkb:P31522	intact:EBI-1396921|ensembl:ENSP00000257604.5|ensembl:ENSP00000396526.2|uniprotkb:A8K5L6|uniprotkb:B4DI89|intact:EBI-28969419	intact:EBI-20818206|uniprotkb:Q0WHB0	psi-mi:trad1_human(display_long)|uniprotkb:TRAFD1(gene name)|psi-mi:TRAFD1(display_short)|uniprotkb:FLN29(gene name synonym)|uniprotkb:Protein FLN29(gene name synonym)	psi-mi:psaa_yerpe(display_long)|uniprotkb:psaA(gene name)|psi-mi:psaA(display_short)|uniprotkb:Adhesin(gene name synonym)|uniprotkb:Antigen 4(gene name synonym)|uniprotkb:YPO1303(locus name)|uniprotkb:YP_1289(locus name)|uniprotkb:y2882(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818223|imex:IM-26497-764	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137378.1|refseq:NP_006691.1|ensembl:ENSG00000135148.12(gene)|ensembl:ENST00000257604.9(transcript)|ensembl:ENST00000412615.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0046872""(metal ion binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR049439|interpro:IPR051986|mint:O14545|rcsb pdb:2D9K|panther:PTHR16295(orthology-group)"	"mint:P31522|interpro:IPR053731|interpro:IPR048725|refseq:WP_002208794.1|refseq:YP_002346328.1|go:""GO:0009289""(pilus)|rcsb pdb:4F8L|rcsb pdb:4F8N|rcsb pdb:4F8O|rcsb pdb:4F8P|rcsb pdb:5LN4"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:hDY19qxNvWdsjDOoUEpuYfe0cdA9606	rogid:OfHbxyDCt84OqDdpWDr4uy7aggw632	intact-crc:89736E4E9912C1E3|rigid:ovti35r5Qp4dTiE5exGRwGaiZjo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P10253	uniprotkb:Q8ZG77	intact:EBI-2830238|uniprotkb:Q8IWE7|uniprotkb:Q09GN4|uniprotkb:Q16302|uniprotkb:Q14351|ensembl:ENSP00000305692.3|ensembl:ENSP00000374665.3|ensembl:ENSP00000458306.2|ensembl:ENSP00000460543.2|ensembl:ENSP00000516980.1|ensembl:ENSP00000516982.1|ensembl:ENSP00000519347.1|ensembl:ENSP00000519348.1	intact:EBI-20592302|uniprotkb:Q0WGY2|uniprotkb:Q74VI2|uniprotkb:Q8D056	psi-mi:lyag_human(display_long)|uniprotkb:GAA(gene name)|psi-mi:GAA(display_short)|uniprotkb:Acid maltase(gene name synonym)|uniprotkb:Aglucosidase alfa(gene name synonym)	psi-mi:ompa_yerpe(display_long)|uniprotkb:Outer membrane porin A(gene name synonym)|uniprotkb:y2735(locus name)|uniprotkb:ompA(gene name)|psi-mi:ompA(display_short)|uniprotkb:ompA1(gene name synonym)|uniprotkb:YPO1435(locus name)|uniprotkb:YP_1326(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818241|imex:IM-26497-420	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:308552""|efo:""Orphanet:420429""|ensembl:ENSG00000171298.15(gene)|ensembl:ENSG00000291507.1(gene)|ensembl:ENST00000302262.8(transcript)|ensembl:ENST00000390015.7(transcript)|ensembl:ENST00000570803.6(transcript)|ensembl:ENST00000577106.6(transcript)|ensembl:ENST00000707779.1(transcript)|ensembl:ENST00000707781.1(transcript)|ensembl:ENST00000714057.1(transcript)|ensembl:ENST00000714058.1(transcript)|go:""GO:0000023""(maltose metabolic process)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002086""(diaphragm contraction)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0004558""(alpha-1,4-glucosidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0005985""(sucrose metabolic process)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0007040""(lysosome organization)|go:""GO:0007626""(locomotory behavior)|go:""GO:0009888""(tissue development)|go:""GO:0016020""(membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035904""(aorta development)|go:""GO:0043181""(vacuolar sequestering)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0050884""(neuromuscular process controlling posture)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0060048""(cardiac muscle contraction)|go:""GO:0061723""(glycophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090599""(alpha-glucosidase activity)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0120282""(autolysosome lumen)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR000519(P-type trefoil)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017957|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|interpro:IPR044913|interpro:IPR048395|mint:P10253|rcsb pdb:5KZW|rcsb pdb:5KZX|rcsb pdb:5NN3|rcsb pdb:5NN4|rcsb pdb:5NN5|rcsb pdb:5NN6|rcsb pdb:5NN8|rcsb pdb:7P2Z|rcsb pdb:7P32|reactome:R-HSA-5357609|reactome:R-HSA-6798695|reactome:R-HSA-70221|refseq:NP_000143.2|refseq:NP_001073271.1|refseq:NP_001073272.1|refseq:XP_005257250.1|refseq:XP_005257251.1|panther:PTHR22762(orthology-group)"	"interpro:IPR050330|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|refseq:WP_002213066.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR002368(Outer membrane protein, OmpA)|panther:PTHR30128(orthology-group)|refseq:YP_002346456.1|mint:Q8ZG77"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:LqHRnythO4WRf8H74OqWoImqZJA9606	rogid:q86tZqya2906j6c/oL0NQ6Kmy84632	intact-crc:B17347EBE42606D2|rigid:GGqR/gCGcPPhCFQrQvlVnnnzWGI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43707	uniprotkb:Q8D0P1	intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|uniprotkb:A4K467|ensembl:ENSP00000252699.2|ensembl:ENSP00000489220.1	intact:EBI-2856506|uniprotkb:Q8ZFL9|uniprotkb:Q0WGA3	psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)	psi-mi:chey_yerpe(display_long)|uniprotkb:cheY(gene name)|psi-mi:cheY(display_short)|uniprotkb:YPO1680(locus name)|uniprotkb:y1842(locus name)|uniprotkb:YP_1810(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818271|imex:IM-26497-616	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:656""|ensembl:ENSG00000130402.14(gene)|ensembl:ENSG00000282844.2(gene)|ensembl:ENST00000252699.7(transcript)|ensembl:ENST00000634960.2(transcript)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001725""(stress fiber)|go:""GO:0001882""(nucleoside binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030050""(vesicle transport along actin filament)|go:""GO:0030054""(cell junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031143""(pseudopodium)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032417""(""positive regulation of sodium:proton antiporter activity"")|go:""GO:0032991""(protein-containing complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0042995""(cell projection)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051015""(actin filament binding)|go:""GO:0055001""(muscle cell development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|go:""GO:1900025""(negative regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|refseq:NP_004915.2|dip:DIP-33179N|panther:PTHR11915(orthology-group)"	"mint:Q8D0P1|interpro:IPR011006(CheY-like)|interpro:IPR001789(Signal transduction response regulator, receiver region)|refseq:WP_002210873.1|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|interpro:IPR052048|refseq:YP_002346685.1|panther:PTHR43228(orthology-group)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/28	rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606	rogid:wf5r24m07Zgglm31fBnlvBt1VVY632	intact-crc:B112FFFF2CFD99D7|rigid:JjyfZk1jHtVQyZ+X6EFxq1qUHHk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q08117	uniprotkb:Q8ZG77	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	intact:EBI-20592302|uniprotkb:Q0WGY2|uniprotkb:Q74VI2|uniprotkb:Q8D056	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:ompa_yerpe(display_long)|uniprotkb:Outer membrane porin A(gene name synonym)|uniprotkb:y2735(locus name)|uniprotkb:ompA(gene name)|psi-mi:ompA(display_short)|uniprotkb:ompA1(gene name synonym)|uniprotkb:YPO1435(locus name)|uniprotkb:YP_1326(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818259|imex:IM-26497-732	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"interpro:IPR050330|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|refseq:WP_002213066.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR002368(Outer membrane protein, OmpA)|panther:PTHR30128(orthology-group)|refseq:YP_002346456.1|mint:Q8ZG77"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:q86tZqya2906j6c/oL0NQ6Kmy84632	intact-crc:00945C783FA14C34|rigid:IOSBerH4OxVmEwq0XWFCEBBU6Mk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O15162	uniprotkb:Q8ZG77	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	intact:EBI-20592302|uniprotkb:Q0WGY2|uniprotkb:Q74VI2|uniprotkb:Q8D056	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	psi-mi:ompa_yerpe(display_long)|uniprotkb:Outer membrane porin A(gene name synonym)|uniprotkb:y2735(locus name)|uniprotkb:ompA(gene name)|psi-mi:ompA(display_short)|uniprotkb:ompA1(gene name synonym)|uniprotkb:YPO1435(locus name)|uniprotkb:YP_1326(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818265|imex:IM-26497-430	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	"interpro:IPR050330|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|refseq:WP_002213066.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR002368(Outer membrane protein, OmpA)|panther:PTHR30128(orthology-group)|refseq:YP_002346456.1|mint:Q8ZG77"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:q86tZqya2906j6c/oL0NQ6Kmy84632	intact-crc:7618CC1B01C5CB64|rigid:unDGp+G0mCIYeYLbKVa9YA2UTWU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P48634	uniprotkb:Q8ZG77	intact:EBI-347545|uniprotkb:Q05BK4|uniprotkb:Q4LE37|uniprotkb:Q8MGQ9|uniprotkb:O95875|uniprotkb:Q5SQ29|uniprotkb:Q5SQ30|uniprotkb:Q5ST84|uniprotkb:Q5STX6|uniprotkb:Q5STX7|uniprotkb:Q68DW9|uniprotkb:Q6P9P7|uniprotkb:Q6PIN1|uniprotkb:Q96QC6|uniprotkb:B0UZL3|uniprotkb:B0UZE9|uniprotkb:B0UX77|ensembl:ENSP00000365175.4|ensembl:ENSP00000365201.2|ensembl:ENSP00000372947.2|ensembl:ENSP00000372956.4|ensembl:ENSP00000387477.2|ensembl:ENSP00000387910.1|ensembl:ENSP00000396812.2|ensembl:ENSP00000400540.2|ensembl:ENSP00000404619.1|ensembl:ENSP00000408226.1|ensembl:ENSP00000409444.2|ensembl:ENSP00000413977.2|ensembl:ENSP00000415182.1|ensembl:ENSP00000415363.1	intact:EBI-20592302|uniprotkb:Q0WGY2|uniprotkb:Q74VI2|uniprotkb:Q8D056	psi-mi:prc2a_human(display_long)|uniprotkb:HLA-B-associated transcript 2(gene name synonym)|uniprotkb:PRRC2A(gene name)|psi-mi:PRRC2A(display_short)|uniprotkb:G2(gene name synonym)|uniprotkb:Protein G2(gene name synonym)|uniprotkb:BAT2(gene name synonym)|uniprotkb:Large proline-rich protein BAT2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2A(gene name synonym)	psi-mi:ompa_yerpe(display_long)|uniprotkb:Outer membrane porin A(gene name synonym)|uniprotkb:y2735(locus name)|uniprotkb:ompA(gene name)|psi-mi:ompA(display_short)|uniprotkb:ompA1(gene name synonym)|uniprotkb:YPO1435(locus name)|uniprotkb:YP_1326(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818253|imex:IM-26497-614	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_542417.2|refseq:NP_004629.3|ensembl:ENSG00000204469.13(gene)|ensembl:ENSG00000206427.11(gene)|ensembl:ENSG00000225164.9(gene)|ensembl:ENSG00000225748.9(gene)|ensembl:ENSG00000226618.9(gene)|ensembl:ENSG00000231370.9(gene)|ensembl:ENSG00000231825.9(gene)|ensembl:ENST00000376007.8(transcript)|ensembl:ENST00000376033.3(transcript)|ensembl:ENST00000383455.2(transcript)|ensembl:ENST00000383464.8(transcript)|ensembl:ENST00000414956.1(transcript)|ensembl:ENST00000416335.1(transcript)|ensembl:ENST00000422962.1(transcript)|ensembl:ENST00000428775.1(transcript)|ensembl:ENST00000430737.6(transcript)|ensembl:ENST00000432252.1(transcript)|ensembl:ENST00000435971.6(transcript)|ensembl:ENST00000439762.6(transcript)|ensembl:ENST00000454306.6(transcript)|ensembl:ENST00000458561.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:P48634|panther:PTHR14038(orthology-group)"	"interpro:IPR050330|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0015288""(porin activity)|go:""GO:0046930""(pore complex)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|refseq:WP_002213066.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR002368(Outer membrane protein, OmpA)|panther:PTHR30128(orthology-group)|refseq:YP_002346456.1|mint:Q8ZG77"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:6XZhA7FHJ4ckoWPf1yI/OnaNwjo9606	rogid:q86tZqya2906j6c/oL0NQ6Kmy84632	intact-crc:392470B2332CB714|rigid:NOPmDsOhQK23B4lr8a7m+abp3KQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:A0A2U2GVX8	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-2864277|uniprotkb:Q74U22|uniprotkb:Q0WF66|uniprotkb:Q7CID4|uniprotkb:A0A384LJV4	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:a0a2u2gvx8_yerpe(display_long)|uniprotkb:YPO2090(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818277|imex:IM-26497-576	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	interpro:IPR008713(Bacteriophage Lambda NinG)|mint:A0A2U2GVX8|refseq:WP_002211735.1|refseq:YP_002347072.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:NfYXK1H8rOYnW6x1pX4uF9a1Ztk632	intact-crc:47BCD16CEF43BC08|rigid:mWVz87svytI57qJqnO1X9pvVdA4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15853	uniprotkb:A0A384KL23	intact:EBI-1055994|uniprotkb:Q15851|uniprotkb:Q15852|uniprotkb:O00671|uniprotkb:O00709|uniprotkb:Q05750|uniprotkb:Q07952|uniprotkb:Q6FI33|ensembl:ENSP00000222305.2|uniprotkb:Q6YI47	intact:EBI-20592225|uniprotkb:A0A3G5LCU0|uniprotkb:A0A2S9PAT5|uniprotkb:Q0WCX0|uniprotkb:A0A5P8YLR8	psi-mi:usf2_human(display_long)|uniprotkb:USF2(gene name)|psi-mi:USF2(display_short)|uniprotkb:FOS-interacting protein(gene name synonym)|uniprotkb:Upstream transcription factor 2(gene name synonym)|uniprotkb:Major late transcription factor 2(gene name synonym)|uniprotkb:BHLHB12(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 12(gene name synonym)	psi-mi:a0a384kl23_yerpe(display_long)|uniprotkb:YPO2940(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818488|imex:IM-26497-534	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003358.1|refseq:NP_997174.1|ensembl:ENSG00000105698.16(gene)|ensembl:ENST00000222305.8(transcript)|go:""GO:0000430""(regulation of transcription from RNA polymerase II promoter by glucose)|go:""GO:0000432""(positive regulation of transcription from RNA polymerase II promoter by glucose)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007595""(lactation)|go:""GO:0010255""(glucose mediated signaling pathway)|go:""GO:0019086""(late viral transcription)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR051732|mint:Q15853|rcsb pdb:8IA3|reactome:R-HSA-9018519|refseq:NP_001308079.1|panther:PTHR46117(orthology-group)"	"interpro:IPR050263|go:""GO:0009289""(pilus)|go:""GO:0043709""(cell adhesion involved in single-species biofilm formation)|interpro:IPR000259(Fimbrial protein)|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|panther:PTHR33420(orthology-group)|refseq:YP_002347868.1|mint:A0A384KL23"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:lEFfsCJcH99GmZndMiaVI3I4EaA9606	rogid:MuYUsndYAjFtJ9rQDWl+Jk24p2c632	intact-crc:313DB536EA15565D|rigid:37izPVs6P6rY3J/5eegLEBl9AVU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96NU1	uniprotkb:A0A5P8YHS1	intact:EBI-14067109|ensembl:ENSP00000342313.3|uniprotkb:A2AA76|uniprotkb:I7FV78|uniprotkb:I7FV81|uniprotkb:I7G0Z6|uniprotkb:Q5SV96|uniprotkb:Q5SV99|uniprotkb:Q5SVA0|uniprotkb:Q8N195|uniprotkb:Q8TB59	intact:EBI-20818378|uniprotkb:Q0WD22|uniprotkb:Q74S82|uniprotkb:Q7CJM8|uniprotkb:A0A0H2W6J0|uniprotkb:A0A384LKH3	psi-mi:sam11_human(display_long)|uniprotkb:SAMD11(gene name)|psi-mi:SAMD11(display_short)	psi-mi:a0a5p8yhs1_yerpe(display_long)|uniprotkb:YPO2881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818425|imex:IM-26497-676	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000187634.13(gene)|ensembl:ENST00000342066.8(transcript)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0035102""(PRC1 complex)|go:""GO:0042393""(histone binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046548""(retinal rod cell development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96NU1|refseq:NP_689699.2|panther:PTHR12247(orthology-group)"	mint:A0A5P8YHS1|refseq:WP_002209819.1|interpro:IPR013360(Pilus biogenesis/stability type IV, PilW)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002347816.1|interpro:IPR051012	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:xiTMZ5GCBP6+S1JfvGRfZGM+tIM9606	rogid:Cw3Q4dQP076SRhjDt2I5Ae0VRYU632	intact-crc:89B817DC21E99CF9|rigid:Nmn6j+q0lRU7Sowhy4UdBTa7GNs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O94876	uniprotkb:Q0WEL2	intact:EBI-2820525|uniprotkb:Q8IXM8|uniprotkb:Q68E06|uniprotkb:A8K5Y3|uniprotkb:B4DE04|ensembl:ENSP00000376930.3	intact:EBI-20818322|uniprotkb:A0A3G5L4J1|uniprotkb:A0A2S9PLW7|uniprotkb:A0A5P8YFM4	psi-mi:tmcc1_human(display_long)|uniprotkb:TMCC1(gene name)|psi-mi:TMCC1(display_short)|uniprotkb:KIAA0779(gene name synonym)	psi-mi:q0wel2_yerpe(display_long)|uniprotkb:rstB(gene name)|psi-mi:rstB(display_short)|uniprotkb:uspT(gene name synonym)|uniprotkb:YPO2309(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818366|imex:IM-26497-578	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011510874.1|refseq:XP_011510875.1|refseq:XP_011510878.1|refseq:XP_011510881.1|refseq:XP_011510884.1|refseq:NP_001017395.2|refseq:NP_001121696.1|refseq:XP_006713605.1|refseq:XP_006713606.1|refseq:XP_006713607.1|ensembl:ENSG00000172765.19(gene)|ensembl:ENST00000393238.8(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016197""(endosomal transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0090148""(membrane fission)|go:""GO:0097750""(endosome membrane tubulation)|go:""GO:0140284""(endoplasmic reticulum-endosome membrane contact site)|go:""GO:0140285""(endosome fission)|interpro:IPR019394|mint:O94876|refseq:XP_016861420.1|refseq:XP_016861421.1|refseq:XP_016861422.1|panther:PTHR17613(orthology-group)"	"mint:Q0WEL2|interpro:IPR050980|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR036890|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR036097|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:YP_002347276.1|panther:PTHR44936(orthology-group)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005886""(plasma membrane)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:gxHP7LGKWajp9+7rW6Llm1pNhTY9606	rogid:jhi7t3mjsVwEdX1tKg452Dw+4dU632	intact-crc:1E0D48E874ADF613|rigid:KV69wdtCyNVpFYLskeconnEU7BM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P61289	uniprotkb:A0A380PIN9	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794.1|intact:EBI-21352060	intact:EBI-20818560|uniprotkb:A0A3G5L991|uniprotkb:A0A2S9PKB5|uniprotkb:Q0W9Y3|uniprotkb:A0A6B3T4U3	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:a0a380pin9_yerpe(display_long)|uniprotkb:YPO4044(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818573|imex:IM-26497-440	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467.12(gene)|ensembl:ENST00000590720.6(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0002039""(p53 binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008537""(proteasome activator complex)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|rcsb pdb:7YQC|rcsb pdb:7YQD|reactome:R-HSA-9907900|panther:PTHR10660(orthology-group)"	"mint:A0A380PIN9|interpro:IPR050263|refseq:WP_002209597.1|interpro:IPR000259(Fimbrial protein)|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|refseq:YP_002348905.1|panther:PTHR33420(orthology-group)|go:""GO:0009289""(pilus)|go:""GO:0043709""(cell adhesion involved in single-species biofilm formation)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:TxZIZTi9HZF5P8+cfyPxRyrvDsY632	intact-crc:39DB9363D5ED3118|rigid:gwDCIYR9GAFG6uld/APYR7c0Nqw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A7MCY6	uniprotkb:A0A5P8YHS1	intact:EBI-359969|uniprotkb:Q14DW3|uniprotkb:O94873|uniprotkb:B2RZG6|ensembl:ENSP00000354777.3|ensembl:ENSP00000462339.2	intact:EBI-20818378|uniprotkb:Q0WD22|uniprotkb:Q74S82|uniprotkb:Q7CJM8|uniprotkb:A0A0H2W6J0|uniprotkb:A0A384LKH3	psi-mi:tbkb1_human(display_long)|uniprotkb:TBKBP1(gene name)|psi-mi:TBKBP1(display_short)|uniprotkb:SINTBAD(gene name synonym)|uniprotkb:KIAA0775(gene name synonym)	psi-mi:a0a5p8yhs1_yerpe(display_long)|uniprotkb:YPO2881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818443|imex:IM-26497-734	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055541.1|refseq:XP_005257916.1|refseq:XP_005257917.1|refseq:XP_005257918.1|refseq:XP_005257919.1|dip:DIP-27604N|ensembl:ENSG00000198933.11(gene)|ensembl:ENST00000361722.7(transcript)|ensembl:ENST00000578982.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:1902554""(serine/threonine protein kinase complex)|interpro:IPR024581|interpro:IPR041641|interpro:IPR051891|mint:A7MCY6|panther:PTHR14432(orthology-group)"	mint:A0A5P8YHS1|refseq:WP_002209819.1|interpro:IPR013360(Pilus biogenesis/stability type IV, PilW)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002347816.1|interpro:IPR051012	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:Hf7hEVRztbT681BKO7sMjh1EwX09606	rogid:Cw3Q4dQP076SRhjDt2I5Ae0VRYU632	intact-crc:F8C39063C0662899|rigid:zZvbloP99NrYk6ua/qpUiX1G6As	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q08379	uniprotkb:A0A5P8YHS1	intact:EBI-618309|intact:EBI-28970132|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|ensembl:ENSP00000416097.4|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-20818378|uniprotkb:Q0WD22|uniprotkb:Q74S82|uniprotkb:Q7CJM8|uniprotkb:A0A0H2W6J0|uniprotkb:A0A384LKH3	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:a0a5p8yhs1_yerpe(display_long)|uniprotkb:YPO2881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818407|imex:IM-26497-674	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004477.3|ensembl:ENSG00000167110.19(gene)|ensembl:ENST00000421699.8(transcript)|go:""GO:0000137""(Golgi cis cisterna)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000922""(spindle pole)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005874""(microtubule)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007030""(Golgi organization)|go:""GO:0007098""(centrosome cycle)|go:""GO:0008017""(microtubule binding)|go:""GO:0008356""(asymmetric cell division)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0015031""(protein transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0060050""(positive regulation of protein glycosylation)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090161""(Golgi ribbon formation)|go:""GO:0090166""(Golgi disassembly)|go:""GO:0090306""(meiotic spindle assembly)|go:""GO:0090307""(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|dip:DIP-34271N|panther:PTHR10881(orthology-group)"	mint:A0A5P8YHS1|refseq:WP_002209819.1|interpro:IPR013360(Pilus biogenesis/stability type IV, PilW)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002347816.1|interpro:IPR051012	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:Cw3Q4dQP076SRhjDt2I5Ae0VRYU632	intact-crc:39546B8BE6E07603|rigid:SgoEp9ThDCUo1deJgVZcbPFXEFw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q08117	uniprotkb:A0A5P8YHS1	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	intact:EBI-20818378|uniprotkb:Q0WD22|uniprotkb:Q74S82|uniprotkb:Q7CJM8|uniprotkb:A0A0H2W6J0|uniprotkb:A0A384LKH3	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:a0a5p8yhs1_yerpe(display_long)|uniprotkb:YPO2881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818401|imex:IM-26497-516	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	mint:A0A5P8YHS1|refseq:WP_002209819.1|interpro:IPR013360(Pilus biogenesis/stability type IV, PilW)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002347816.1|interpro:IPR051012	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:Cw3Q4dQP076SRhjDt2I5Ae0VRYU632	intact-crc:77C9094480656E0F|rigid:oNm1qMeKdpIwvOP1N/T8y75XXY8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q15834	uniprotkb:A0A2S9PCS4	intact:EBI-739674|uniprotkb:Q96HA0|uniprotkb:B2R598|ensembl:ENSP00000311695.2	intact:EBI-20818283|uniprotkb:A0A5P8YF53|uniprotkb:Q7CIE7|uniprotkb:Q0WF47	psi-mi:cc85b_human(display_long)|uniprotkb:CCDC85B(gene name)|psi-mi:CCDC85B(display_short)|uniprotkb:Hepatitis delta antigen-interacting protein A(gene name synonym)|uniprotkb:DIPA(gene name synonym)	psi-mi:a0a2s9pcs4_yerpe(display_long)|uniprotkb:YPO2113(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818298|imex:IM-26497-672	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006839.2|ensembl:ENSG00000175602.4(gene)|ensembl:ENST00000312579.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005912""(adherens junction)|go:""GO:0030154""(cell differentiation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070097""(delta-catenin binding)|interpro:IPR019359|mint:Q15834|panther:PTHR13546(orthology-group)"	mint:A0A2S9PCS4|refseq:YP_002347091.1|refseq:WP_002211716.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:DUMY8gDRLRjC4Iu+z7SVBZ6sQkY9606	rogid:z9HRzlORUfpYWzcmHkjF6B/X3ec632	intact-crc:21F860AAE4D7E78B|rigid:F15yXTENuniDuNijvFDN2DITXxQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q16799	uniprotkb:Q0WEL2	intact:EBI-742130|uniprotkb:Q16800|uniprotkb:Q16801|uniprotkb:Q5BKZ4|intact:EBI-2801527|uniprotkb:Q9BQ59|ensembl:ENSP00000267484.5	intact:EBI-20818322|uniprotkb:A0A3G5L4J1|uniprotkb:A0A2S9PLW7|uniprotkb:A0A5P8YFM4	psi-mi:rtn1_human(display_long)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)	psi-mi:q0wel2_yerpe(display_long)|uniprotkb:rstB(gene name)|psi-mi:rstB(display_short)|uniprotkb:uspT(gene name synonym)|uniprotkb:YPO2309(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818372|imex:IM-26497-580	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066959.1|refseq:NP_996734.1|ensembl:ENSG00000139970.18(gene)|ensembl:ENST00000267484.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007420""(brain development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030425""(dendrite)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0071787""(endoplasmic reticulum tubular network formation)|go:""GO:1902430""(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|interpro:IPR046964|mint:Q16799|panther:PTHR45799(orthology-group)"	"mint:Q0WEL2|interpro:IPR050980|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR036890|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR036097|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:YP_002347276.1|panther:PTHR44936(orthology-group)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005886""(plasma membrane)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:oBpsOfx4vuPEjlUg5McyYDfqKzo9606	rogid:jhi7t3mjsVwEdX1tKg452Dw+4dU632	intact-crc:DF1816101E7E49B8|rigid:Vx3/zCGeGTkHPu1eTUB/QkpqUp8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:Q7CKI5	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20818506|uniprotkb:Q74X65	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:nlpi_yerpe(display_long)|uniprotkb:nlpI(gene name)|psi-mi:nlpI(display_short)|uniprotkb:YPO3489(locus name)|uniprotkb:YP_0594(locus name)|uniprotkb:y0695(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818530|imex:IM-26497-478	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"mint:Q7CKI5|interpro:IPR050498|refseq:WP_002209260.1|interpro:IPR023605|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002348378.1|panther:PTHR12558(orthology-group)|go:""GO:0005886""(plasma membrane)|go:""GO:0051301""(cell division)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:yLU4XUkO7AJbsp+IPOecoVeJMrg632	intact-crc:29A777FA6A3B7EFF|rigid:gkV5O1V8iVFwT/BRtJAzTEp80Yg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:A0A5P8YHS1	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20818378|uniprotkb:Q0WD22|uniprotkb:Q74S82|uniprotkb:Q7CJM8|uniprotkb:A0A0H2W6J0|uniprotkb:A0A384LKH3	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:a0a5p8yhs1_yerpe(display_long)|uniprotkb:YPO2881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818431|imex:IM-26497-520	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	mint:A0A5P8YHS1|refseq:WP_002209819.1|interpro:IPR013360(Pilus biogenesis/stability type IV, PilW)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002347816.1|interpro:IPR051012	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:Cw3Q4dQP076SRhjDt2I5Ae0VRYU632	intact-crc:62D0F504F554B6EC|rigid:ozyeUVCqSxyAQu5KBY8v3f2sYHk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H0F6	uniprotkb:A0A5P8YI02	intact:EBI-3942966|uniprotkb:D3DWL3|uniprotkb:Q8IXF5|uniprotkb:Q8IXF6|uniprotkb:A6NEG3|uniprotkb:Q8TB25|uniprotkb:Q9BUE4|uniprotkb:Q8N2E7|uniprotkb:C0L3L2|ensembl:ENSP00000381698.2	intact:EBI-20818455|uniprotkb:A0A3G5LEL3|uniprotkb:Q0WCZ9|uniprotkb:A0A2S9PGR0|uniprotkb:A0A384KE26|uniprotkb:A0A6B3T6X1	psi-mi:shrpn_human(display_long)|uniprotkb:SHARPIN(gene name)|psi-mi:SHARPIN(display_short)|uniprotkb:SIPL1(gene name synonym)|uniprotkb:Shank-associated RH domain-interacting protein(gene name synonym)|uniprotkb:Shank-interacting protein-like 1(gene name synonym)|uniprotkb:PSEC0216(orf name)	psi-mi:a0a5p8yi02_yerpe(display_long)|uniprotkb:ail(gene name)|psi-mi:ail(display_short)|uniprotkb:YPO2905(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818470|imex:IM-26497-596	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_112236.3|refseq:XP_016869377.1|dip:DIP-57842N|ensembl:ENSG00000179526.17(gene)|ensembl:ENST00000398712.7(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0030262""(apoptotic nuclear changes)|go:""GO:0030425""(dendrite)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031424""(keratinization)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0071797""(LUBAC complex)|go:""GO:0097039""(protein linear polyubiquitination)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000348""(regulation of CD40 signaling pathway)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR031912|interpro:IPR036443|interpro:IPR051628|mint:Q9H0F6|rcsb pdb:4EMO|rcsb pdb:5X0W|rcsb pdb:8K6P|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-6794361"	"mint:A0A5P8YI02|interpro:IPR051723|interpro:IPR027385|refseq:WP_002227864.1|interpro:IPR000758(Virulence-related outer membrane protein)|interpro:IPR011250(Outer membrane protein, beta-barrel)|refseq:YP_002347839.1|panther:PTHR35892(orthology-group)|go:""GO:0009279""(cell outer membrane)|go:""GO:0044384""(host outer membrane)|rcsb pdb:5VJ8"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:+RGl3JO1zsGCdaInDn20yhNZs0E9606	rogid:tELQ/peG5Qb0HEs9Spa5/KQ+1r4632	intact-crc:A70AAC52423ACF48|rigid:iGg/TDlTHzOgCP9y05hVm/x54t8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9ULS5	uniprotkb:Q0WEL2	intact:EBI-2800326|uniprotkb:Q8IWB2|ensembl:ENSP00000261226.4	intact:EBI-20818322|uniprotkb:A0A3G5L4J1|uniprotkb:A0A2S9PLW7|uniprotkb:A0A5P8YFM4	psi-mi:tmcc3_human(display_long)|uniprotkb:KIAA1145(gene name synonym)|uniprotkb:TMCC3(gene name)|psi-mi:TMCC3(display_short)	psi-mi:q0wel2_yerpe(display_long)|uniprotkb:rstB(gene name)|psi-mi:rstB(display_short)|uniprotkb:uspT(gene name synonym)|uniprotkb:YPO2309(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818348|imex:IM-26497-618	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_065749.2|ensembl:ENSG00000057704.13(gene)|ensembl:ENST00000261226.9(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0012505""(endomembrane system)|go:""GO:0042802""(identical protein binding)|go:""GO:0071889""(14-3-3 protein binding)|interpro:IPR019394|mint:Q9ULS5|refseq:NP_001287965.1|panther:PTHR17613(orthology-group)"	"mint:Q0WEL2|interpro:IPR050980|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR036890|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR036097|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:YP_002347276.1|panther:PTHR44936(orthology-group)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005886""(plasma membrane)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:60igKcQ3YW+Bvz/cDjtnwAS8azc9606	rogid:jhi7t3mjsVwEdX1tKg452Dw+4dU632	intact-crc:050371341E322489|rigid:dHGvWdbsLy06wFre+DlSFTCVgwU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O60711	uniprotkb:A0A2S9PCS4	intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512.2	intact:EBI-20818283|uniprotkb:A0A5P8YF53|uniprotkb:Q7CIE7|uniprotkb:Q0WF47	psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym)	psi-mi:a0a2s9pcs4_yerpe(display_long)|uniprotkb:YPO2113(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818304|imex:IM-26497-514	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137467.1|refseq:NP_004802.1|refseq:NP_001294880.1|ensembl:ENSG00000110031.13(gene)|ensembl:ENST00000395074.7(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042995""(cell projection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|panther:PTHR24216(orthology-group)"	mint:A0A2S9PCS4|refseq:YP_002347091.1|refseq:WP_002211716.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606	rogid:z9HRzlORUfpYWzcmHkjF6B/X3ec632	intact-crc:10174D48259B6A43|rigid:Cf2JSpZrgm9Pf+9aZMeKvVO687U	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H0F6	uniprotkb:A0A5P8YHS1	intact:EBI-3942966|uniprotkb:D3DWL3|uniprotkb:Q8IXF5|uniprotkb:Q8IXF6|uniprotkb:A6NEG3|uniprotkb:Q8TB25|uniprotkb:Q9BUE4|uniprotkb:Q8N2E7|uniprotkb:C0L3L2|ensembl:ENSP00000381698.2	intact:EBI-20818378|uniprotkb:Q0WD22|uniprotkb:Q74S82|uniprotkb:Q7CJM8|uniprotkb:A0A0H2W6J0|uniprotkb:A0A384LKH3	psi-mi:shrpn_human(display_long)|uniprotkb:SHARPIN(gene name)|psi-mi:SHARPIN(display_short)|uniprotkb:SIPL1(gene name synonym)|uniprotkb:Shank-associated RH domain-interacting protein(gene name synonym)|uniprotkb:Shank-interacting protein-like 1(gene name synonym)|uniprotkb:PSEC0216(orf name)	psi-mi:a0a5p8yhs1_yerpe(display_long)|uniprotkb:YPO2881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818437|imex:IM-26497-438	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_112236.3|refseq:XP_016869377.1|dip:DIP-57842N|ensembl:ENSG00000179526.17(gene)|ensembl:ENST00000398712.7(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0030262""(apoptotic nuclear changes)|go:""GO:0030425""(dendrite)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031424""(keratinization)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0071797""(LUBAC complex)|go:""GO:0097039""(protein linear polyubiquitination)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000348""(regulation of CD40 signaling pathway)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR031912|interpro:IPR036443|interpro:IPR051628|mint:Q9H0F6|rcsb pdb:4EMO|rcsb pdb:5X0W|rcsb pdb:8K6P|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-6794361"	mint:A0A5P8YHS1|refseq:WP_002209819.1|interpro:IPR013360(Pilus biogenesis/stability type IV, PilW)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002347816.1|interpro:IPR051012	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:+RGl3JO1zsGCdaInDn20yhNZs0E9606	rogid:Cw3Q4dQP076SRhjDt2I5Ae0VRYU632	intact-crc:640756CF5D0E55E5|rigid:Jk0HUa9AhLbydOrWSThAlJfhzjw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P63172	uniprotkb:A0A384KL23	intact:EBI-1176455|uniprotkb:Q15763|uniprotkb:Q5VTU4|ensembl:ENSP00000356056.3	intact:EBI-20592225|uniprotkb:A0A3G5LCU0|uniprotkb:A0A2S9PAT5|uniprotkb:Q0WCX0|uniprotkb:A0A5P8YLR8	psi-mi:dylt1_human(display_long)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym)|uniprotkb:Protein CW-1(gene name synonym)|uniprotkb:DYNLT1(gene name)|psi-mi:DYNLT1(display_short)|uniprotkb:TCTEL1(gene name synonym)|uniprotkb:TCTEX1(gene name synonym)|uniprotkb:TCTEX-1(gene name synonym)	psi-mi:a0a384kl23_yerpe(display_long)|uniprotkb:YPO2940(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818494|imex:IM-26497-536	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006510.1|panther:PTHR21255(orthology-group)|dip:DIP-35251N|ensembl:ENSG00000146425.11(gene)|ensembl:ENST00000367089.8(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007399""(nervous system development)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0019060""(intracellular transport of viral protein in host cell)|go:""GO:0030286""(dynein complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043657""(host cell)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051301""(cell division)|go:""GO:0075521""(microtubule-dependent intracellular transport of viral material towards nucleus)|go:""GO:0099503""(secretory vesicle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|mint:P63172|rcsb pdb:5JPW|rcsb pdb:8J07|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGI|reactome:R-HSA-6798695"	"interpro:IPR050263|go:""GO:0009289""(pilus)|go:""GO:0043709""(cell adhesion involved in single-species biofilm formation)|interpro:IPR000259(Fimbrial protein)|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|panther:PTHR33420(orthology-group)|refseq:YP_002347868.1|mint:A0A384KL23"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/28	rogid:RKVyHgf4iNjcY6GfLdIukFOFE+s9606	rogid:MuYUsndYAjFtJ9rQDWl+Jk24p2c632	intact-crc:3EBB9D501A1EFC68|rigid:CVmM7rFfHMi/vTmBA2HhoK0gtnQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:A0A2S9PCS4	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20818283|uniprotkb:A0A5P8YF53|uniprotkb:Q7CIE7|uniprotkb:Q0WF47	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:a0a2s9pcs4_yerpe(display_long)|uniprotkb:YPO2113(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818292|imex:IM-26497-432	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	mint:A0A2S9PCS4|refseq:YP_002347091.1|refseq:WP_002211716.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:z9HRzlORUfpYWzcmHkjF6B/X3ec632	intact-crc:6045999BDD93AC76|rigid:LD9BMt5M6VejRmTsaraDva+A1pk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6PKC3	uniprotkb:A0A5P8YHS1	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	intact:EBI-20818378|uniprotkb:Q0WD22|uniprotkb:Q74S82|uniprotkb:Q7CJM8|uniprotkb:A0A0H2W6J0|uniprotkb:A0A384LKH3	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:a0a5p8yhs1_yerpe(display_long)|uniprotkb:YPO2881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818449|imex:IM-26497-532	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	mint:A0A5P8YHS1|refseq:WP_002209819.1|interpro:IPR013360(Pilus biogenesis/stability type IV, PilW)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002347816.1|interpro:IPR051012	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:Cw3Q4dQP076SRhjDt2I5Ae0VRYU632	intact-crc:AAD145D7A6C0C00F|rigid:OHlKYkJ/oLk0p2a7MI84CSqx4Oc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q04206	uniprotkb:A0A384KL23	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	intact:EBI-20592225|uniprotkb:A0A3G5LCU0|uniprotkb:A0A2S9PAT5|uniprotkb:Q0WCX0|uniprotkb:A0A5P8YLR8	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:a0a384kl23_yerpe(display_long)|uniprotkb:YPO2940(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818500|imex:IM-26497-538	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	"interpro:IPR050263|go:""GO:0009289""(pilus)|go:""GO:0043709""(cell adhesion involved in single-species biofilm formation)|interpro:IPR000259(Fimbrial protein)|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|panther:PTHR33420(orthology-group)|refseq:YP_002347868.1|mint:A0A384KL23"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rogid:MuYUsndYAjFtJ9rQDWl+Jk24p2c632	intact-crc:79A62780BB27E6FA|rigid:bWLcm69osQYP7c7Psjj5YMq6Y2Y	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y228	uniprotkb:Q0WEL2	intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991.1|ensembl:ENSP00000355992.3	intact:EBI-20818322|uniprotkb:A0A3G5L4J1|uniprotkb:A0A2S9PLW7|uniprotkb:A0A5P8YFM4	psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym)	psi-mi:q0wel2_yerpe(display_long)|uniprotkb:rstB(gene name)|psi-mi:rstB(display_short)|uniprotkb:uspT(gene name synonym)|uniprotkb:YPO2309(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818354|imex:IM-26497-436	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790.15(gene)|ensembl:ENST00000367024.5(transcript)|ensembl:ENST00000367025.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0060090""(molecular adaptor activity)|interpro:IPR051176|mint:Q9Y228|panther:PTHR15715(orthology-group)"	"mint:Q0WEL2|interpro:IPR050980|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR036890|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR036097|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:YP_002347276.1|panther:PTHR44936(orthology-group)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005886""(plasma membrane)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606	rogid:jhi7t3mjsVwEdX1tKg452Dw+4dU632	intact-crc:D16F107FBEE9564E|rigid:xyUdNNppDRGvTEz9zUEm3yDyq7o	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H0C5	uniprotkb:Q7CKI5	intact:EBI-935503|uniprotkb:A6NMI8|uniprotkb:Q9BX71|uniprotkb:Q9NWN4|ensembl:ENSP00000261721.4	intact:EBI-20818506|uniprotkb:Q74X65	psi-mi:btbd1_human(display_long)|uniprotkb:BTBD1(gene name)|psi-mi:BTBD1(display_short)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 8(gene name synonym)|uniprotkb:NS5ATP8(gene name synonym)	psi-mi:nlpi_yerpe(display_long)|uniprotkb:nlpI(gene name)|psi-mi:nlpI(display_short)|uniprotkb:YPO3489(locus name)|uniprotkb:YP_0594(locus name)|uniprotkb:y0695(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818524|imex:IM-26497-680	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001011885.1|refseq:NP_079514.1|ensembl:ENSG00000064726.10(gene)|ensembl:ENST00000261721.9(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007517""(muscle organ development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0022008""(neurogenesis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:0043393""(regulation of protein binding)|go:""GO:0097602""(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR012983(PHR)|interpro:IPR038648|mint:Q9H0C5|reactome:R-HSA-8951664|reactome:R-HSA-983168|panther:PTHR45774(orthology-group)"	"mint:Q7CKI5|interpro:IPR050498|refseq:WP_002209260.1|interpro:IPR023605|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002348378.1|panther:PTHR12558(orthology-group)|go:""GO:0005886""(plasma membrane)|go:""GO:0051301""(cell division)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:fRSh7JVRI2O2o8m7WCEjydcX1QM9606	rogid:yLU4XUkO7AJbsp+IPOecoVeJMrg632	intact-crc:1482558247340155|rigid:KaCA/3fwLsH9EnMEFQSqBpksBMo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8N196	uniprotkb:A0A2U2H0Y9	intact:EBI-946167|ensembl:ENSP00000316842.4	intact:EBI-20592206|uniprotkb:A0A380PFV1|uniprotkb:Q0WAD5|uniprotkb:Q74RA0|uniprotkb:Q7CKZ6|uniprotkb:A0A384L2L7	psi-mi:six5_human(display_long)|uniprotkb:SIX5(gene name)|psi-mi:SIX5(display_short)|uniprotkb:DMAHP(gene name synonym)|uniprotkb:DM locus-associated homeodomain protein(gene name synonym)|uniprotkb:Sine oculis homeobox homolog 5(gene name synonym)	psi-mi:a0a2u2h0y9_yerpe(display_long)|uniprotkb:YPO3877(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818542|imex:IM-26497-638	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000177045.11(gene)|ensembl:ENST00000317578.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0002088""(lens development in camera-type eye)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007286""(spermatid development)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0160024""(Leydig cell proliferation)|go:""GO:1902723""(negative regulation of skeletal muscle satellite cell proliferation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR031701|mint:Q8N196|refseq:NP_787071.2|efo:""Orphanet:107""|panther:PTHR10390(orthology-group)"	"interpro:IPR050263|go:""GO:0007155""(cell adhesion)|go:""GO:0009289""(pilus)|interpro:IPR039458|refseq:WP_002211997.1|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|refseq:YP_002348753.1|mint:A0A2U2H0Y9"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:/6UktdCF3v6kReBhbokaJOJyKe49606	rogid:Z2vEIx26i3KjVJslLNlEQhiBB84632	intact-crc:86D24EF226262D72|rigid:5CR/U9HB5WWmd9EqFKpEt754xGc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43294	uniprotkb:Q0WF42	intact:EBI-1051449|uniprotkb:Q9BPW3|uniprotkb:Q9Y2V5|uniprotkb:B2R8D5|ensembl:ENSP00000378332.3	intact:EBI-20818310	psi-mi:tgfi1_human(display_long)|uniprotkb:TGFB1I1(gene name)|psi-mi:TGFB1I1(display_short)|uniprotkb:ARA55(gene name synonym)|uniprotkb:Hydrogen peroxide-inducible clone 5 protein(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 55 kDa(gene name synonym)|uniprotkb:Androgen receptor coactivator 55 kDa protein(gene name synonym)	psi-mi:q0wf42_yerpe(display_long)|uniprotkb:YPO2118(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818316|imex:IM-26497-434	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035919.1|refseq:NP_001158191.1|refseq:NP_057011.2|dip:DIP-5931N|ensembl:ENSG00000140682.19(gene)|ensembl:ENST00000394863.8(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0016363""(nuclear matrix)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045165""(cell fate commitment)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048495""(Roundabout binding)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0070411""(I-SMAD binding)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|interpro:IPR047075|mint:O43294|panther:PTHR24216(orthology-group)"	mint:Q0WF42|interpro:IPR014915(Protein of unknown function DUF1799, phage-related)|refseq:YP_002347096.1|refseq:WP_002214476.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:ekkGbwdFenBhBn0HzJjd4Szi61U9606	rogid:Rz3IsvH6QubU+He6h5M0jH/1rp4632	intact-crc:4B4E39D3B0228F54|rigid:Yq4YWoET8Z+Lkf56NWQ9SRu1SIk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05783	uniprotkb:A0A5P8YHS1	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	intact:EBI-20818378|uniprotkb:Q0WD22|uniprotkb:Q74S82|uniprotkb:Q7CJM8|uniprotkb:A0A0H2W6J0|uniprotkb:A0A384LKH3	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:a0a5p8yhs1_yerpe(display_long)|uniprotkb:YPO2881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818419|imex:IM-26497-770	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	mint:A0A5P8YHS1|refseq:WP_002209819.1|interpro:IPR013360(Pilus biogenesis/stability type IV, PilW)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002347816.1|interpro:IPR051012	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:Cw3Q4dQP076SRhjDt2I5Ae0VRYU632	intact-crc:93FB46EFFA95C2F4|rigid:YkijtLBTkLBsNATBxSyqBUFDgNQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P05783	uniprotkb:A0A5P8YI02	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	intact:EBI-20818455|uniprotkb:A0A3G5LEL3|uniprotkb:Q0WCZ9|uniprotkb:A0A2S9PGR0|uniprotkb:A0A384KE26|uniprotkb:A0A6B3T6X1	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:a0a5p8yi02_yerpe(display_long)|uniprotkb:ail(gene name)|psi-mi:ail(display_short)|uniprotkb:YPO2905(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818482|imex:IM-26497-772	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	"mint:A0A5P8YI02|interpro:IPR051723|interpro:IPR027385|refseq:WP_002227864.1|interpro:IPR000758(Virulence-related outer membrane protein)|interpro:IPR011250(Outer membrane protein, beta-barrel)|refseq:YP_002347839.1|panther:PTHR35892(orthology-group)|go:""GO:0009279""(cell outer membrane)|go:""GO:0044384""(host outer membrane)|rcsb pdb:5VJ8"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:tELQ/peG5Qb0HEs9Spa5/KQ+1r4632	intact-crc:EA876DDE44BF736E|rigid:X91UZCy6O1bWsKNNDytB2DwCvbs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q12846	uniprotkb:Q0WEL2	intact:EBI-744942|uniprotkb:Q15525|uniprotkb:Q6FHE8|uniprotkb:A8MXY0|ensembl:ENSP00000317714.3	intact:EBI-20818322|uniprotkb:A0A3G5L4J1|uniprotkb:A0A2S9PLW7|uniprotkb:A0A5P8YFM4	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:q0wel2_yerpe(display_long)|uniprotkb:rstB(gene name)|psi-mi:rstB(display_short)|uniprotkb:uspT(gene name synonym)|uniprotkb:YPO2309(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818360|imex:IM-26497-620	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004595.2|refseq:NP_001259025.1|ensembl:ENSG00000103496.15(gene)|ensembl:ENST00000313843.8(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0000322""(storage vacuole)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005768""(endosome)|go:""GO:0005773""(vacuole)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006887""(exocytosis)|go:""GO:0006906""(vesicle fusion)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0016230""(sphingomyelin phosphodiesterase activator activity)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0030027""(lamellipodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0032420""(stereocilium)|go:""GO:0032589""(neuron projection membrane)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035493""(SNARE complex assembly)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0036477""(somatodendritic compartment)|go:""GO:0042581""(specific granule)|go:""GO:0043085""(positive regulation of catalytic activity)|go:""GO:0043197""(dendritic spine)|go:""GO:0043219""(lateral loop)|go:""GO:0043311""(positive regulation of eosinophil degranulation)|go:""GO:0045202""(synapse)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0048278""(vesicle docking)|go:""GO:0048284""(organelle fusion)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050921""(positive regulation of chemotaxis)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903575""(cornified envelope assembly)|go:""GO:2000010""(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR045242|mint:Q12846|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|panther:PTHR19957(orthology-group)"	"mint:Q0WEL2|interpro:IPR050980|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR036890|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR036097|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:YP_002347276.1|panther:PTHR44936(orthology-group)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005886""(plasma membrane)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	rogid:jhi7t3mjsVwEdX1tKg452Dw+4dU632	intact-crc:B1EE317D5E2DD271|rigid:19p9RgxPyi6ky383jZop0M+dCsY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q04206	uniprotkb:A0A2U2H0Y9	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	intact:EBI-20592206|uniprotkb:A0A380PFV1|uniprotkb:Q0WAD5|uniprotkb:Q74RA0|uniprotkb:Q7CKZ6|uniprotkb:A0A384L2L7	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:a0a2u2h0y9_yerpe(display_long)|uniprotkb:YPO3877(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818554|imex:IM-26497-598	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	"interpro:IPR050263|go:""GO:0007155""(cell adhesion)|go:""GO:0009289""(pilus)|interpro:IPR039458|refseq:WP_002211997.1|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|refseq:YP_002348753.1|mint:A0A2U2H0Y9"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rogid:Z2vEIx26i3KjVJslLNlEQhiBB84632	intact-crc:31F5DD4A67962EF6|rigid:nv6JLmf4ht7Hldm/Xjo3DlQlXSA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NYJ8	uniprotkb:A0A2U2H0Y9	intact:EBI-358708|uniprotkb:O94838|uniprotkb:Q6I9W8|uniprotkb:Q76N06|uniprotkb:Q9UFP7|uniprotkb:E1P5A0|uniprotkb:B2RCC4|ensembl:ENSP00000356426.1|ensembl:ENSP00000490618.1	intact:EBI-20592206|uniprotkb:A0A380PFV1|uniprotkb:Q0WAD5|uniprotkb:Q74RA0|uniprotkb:Q7CKZ6|uniprotkb:A0A384L2L7	psi-mi:tab2_human(display_long)|uniprotkb:TAB2(gene name)|psi-mi:TAB2(display_short)|uniprotkb:KIAA0733(gene name synonym)|uniprotkb:MAP3K7IP2(gene name synonym)|uniprotkb:TAK1-binding protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase 7-interacting protein 2(gene name synonym)|uniprotkb:TGF-beta-activated kinase 1-binding protein 2(gene name synonym)	psi-mi:a0a2u2h0y9_yerpe(display_long)|uniprotkb:YPO3877(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818548|imex:IM-26497-774	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000055208.20(gene)|ensembl:ENST00000367456.5(transcript)|ensembl:ENST00000637181.2(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0007507""(heart development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010008""(endosome membrane)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR036443|interpro:IPR041911|mint:Q9NYJ8|rcsb pdb:2DAE|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1|rcsb pdb:9AVT|rcsb pdb:9AVW|reactome:R-HSA-1251985|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-9705671|reactome:R-HSA-975163|refseq:NP_001278963.1|refseq:NP_001278964.1|refseq:NP_055908.1|refseq:XP_011533935.1|refseq:XP_016866080.1|refseq:XP_016866081.1|efo:""Orphanet:664401""|efo:""Orphanet:664404""|dip:DIP-27525N|panther:PTHR46253(orthology-group)"	"interpro:IPR050263|go:""GO:0007155""(cell adhesion)|go:""GO:0009289""(pilus)|interpro:IPR039458|refseq:WP_002211997.1|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|refseq:YP_002348753.1|mint:A0A2U2H0Y9"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:hMWL5GobXJSsm8ToWVBF/ZwPX3M9606	rogid:Z2vEIx26i3KjVJslLNlEQhiBB84632	intact-crc:C096812BB2A20793|rigid:EnutsX82awZo1l8/ZvIg/QtARU0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P46379	uniprotkb:A0A5P8YI02	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-20818455|uniprotkb:A0A3G5LEL3|uniprotkb:Q0WCZ9|uniprotkb:A0A2S9PGR0|uniprotkb:A0A384KE26|uniprotkb:A0A6B3T6X1	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:a0a5p8yi02_yerpe(display_long)|uniprotkb:ail(gene name)|psi-mi:ail(display_short)|uniprotkb:YPO2905(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818476|imex:IM-26497-678	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"mint:A0A5P8YI02|interpro:IPR051723|interpro:IPR027385|refseq:WP_002227864.1|interpro:IPR000758(Virulence-related outer membrane protein)|interpro:IPR011250(Outer membrane protein, beta-barrel)|refseq:YP_002347839.1|panther:PTHR35892(orthology-group)|go:""GO:0009279""(cell outer membrane)|go:""GO:0044384""(host outer membrane)|rcsb pdb:5VJ8"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:tELQ/peG5Qb0HEs9Spa5/KQ+1r4632	intact-crc:79E92A1CB2541B4F|rigid:c9k7BI8VRwCd7fonxSHYHaWtp70	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q16570	uniprotkb:A0A2U2H0Y9	intact:EBI-16355853|ensembl:ENSP00000357104.1|uniprotkb:A8YPG5|uniprotkb:O75898|uniprotkb:Q16300|uniprotkb:Q8WWE3|uniprotkb:Q9UJP0|uniprotkb:Q9UKZ5|uniprotkb:Q9UKZ6|uniprotkb:Q9UQE1	intact:EBI-20592206|uniprotkb:A0A380PFV1|uniprotkb:Q0WAD5|uniprotkb:Q74RA0|uniprotkb:Q7CKZ6|uniprotkb:A0A384L2L7	psi-mi:ackr1_human(display_long)|uniprotkb:ACKR1(gene name)|psi-mi:ACKR1(display_short)|uniprotkb:DARC(gene name synonym)|uniprotkb:Duffy antigen/chemokine receptor(gene name synonym)|uniprotkb:FY(gene name synonym)|uniprotkb:Fy glycoprotein(gene name synonym)|uniprotkb:GPD(gene name synonym)|uniprotkb:Glycoprotein D(gene name synonym)|uniprotkb:Plasmodium vivax receptor(gene name synonym)	psi-mi:a0a2u2h0y9_yerpe(display_long)|uniprotkb:YPO3877(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818536|imex:IM-26497-636	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000213088.14(gene)|ensembl:ENST00000368122.4(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0019957""(C-C chemokine binding)|go:""GO:0032642""(regulation of chemokine production)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0070098""(chemokine-mediated signaling pathway)|interpro:IPR005384(Duffy antigen/chemokine receptor)|mint:Q16570|rcsb pdb:4NUU|rcsb pdb:4NUV|rcsb pdb:7P93|rcsb pdb:8A44|rcsb pdb:8JPS|reactome:R-HSA-375276|dip:DIP-3783N|refseq:NP_001116423.1|refseq:NP_002027.2|panther:PTHR14181(orthology-group)"	"interpro:IPR050263|go:""GO:0007155""(cell adhesion)|go:""GO:0009289""(pilus)|interpro:IPR039458|refseq:WP_002211997.1|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|refseq:YP_002348753.1|mint:A0A2U2H0Y9"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:87dtLZQ17bIsJ5+TpomwHbzZlBY9606	rogid:Z2vEIx26i3KjVJslLNlEQhiBB84632	intact-crc:8518AF012311FCD7|rigid:Z31H1ldjl+ymfjxYalh56I0YlsM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43765	uniprotkb:Q0WEL2	intact:EBI-347996|uniprotkb:Q9BTZ9|ensembl:ENSP00000221566.1|ensembl:ENSP00000503397.1|ensembl:ENSP00000504495.1|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-20818322|uniprotkb:A0A3G5L4J1|uniprotkb:A0A2S9PLW7|uniprotkb:A0A5P8YFM4	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:q0wel2_yerpe(display_long)|uniprotkb:rstB(gene name)|psi-mi:rstB(display_short)|uniprotkb:uspT(gene name synonym)|uniprotkb:YPO2309(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818342|imex:IM-26497-768	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000104969.11(gene)|ensembl:ENST00000221566.7(transcript)|ensembl:ENST00000676943.1(transcript)|ensembl:ENST00000677149.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072380""(TRC complex)|go:""GO:1904288""(BAT3 complex binding)|go:""GO:1904293""(negative regulation of ERAD pathway)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000059""(negative regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|interpro:IPR047150|mint:O43765|rcsb pdb:2VYI|rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|refseq:NP_003012.1|refseq:XP_011526480.1|panther:PTHR45831(orthology-group)"	"mint:Q0WEL2|interpro:IPR050980|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR036890|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR036097|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:YP_002347276.1|panther:PTHR44936(orthology-group)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005886""(plasma membrane)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:jhi7t3mjsVwEdX1tKg452Dw+4dU632	intact-crc:2DC792D6CFA3CFC9|rigid:KecE+orJEdjV3sNg88rjddNpZ3o	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P28799	uniprotkb:A0A5P8YHS1	intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|uniprotkb:Q53Y88|uniprotkb:Q540U8|ensembl:ENSP00000053867.2|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1	intact:EBI-20818378|uniprotkb:Q0WD22|uniprotkb:Q74S82|uniprotkb:Q7CJM8|uniprotkb:A0A0H2W6J0|uniprotkb:A0A384LKH3	psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)	psi-mi:a0a5p8yhs1_yerpe(display_long)|uniprotkb:YPO2881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818413|imex:IM-26497-518	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314629""|ensembl:ENSG00000030582.19(gene)|ensembl:ENST00000053867.8(transcript)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0002282""(microglial cell activation involved in immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0007040""(lysosome organization)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0007165""(signal transduction)|go:""GO:0008083""(growth factor activity)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0060266""(negative regulation of respiratory burst involved in inflammatory response)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106016""(positive regulation of inflammatory response to wounding)|go:""GO:1900426""(positive regulation of defense response to bacterium)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1903334""(positive regulation of protein folding)|go:""GO:1903979""(negative regulation of microglial cell activation)|go:""GO:1905247""(positive regulation of aspartic-type peptidase activity)|go:""GO:1905673""(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|rcsb pdb:8T8R|rcsb pdb:8T8S|reactome:R-HSA-6798695|refseq:NP_002078.1|refseq:XP_005257310.1|dip:DIP-41742N|efo:""Orphanet:100069""|efo:""Orphanet:100070""|efo:""Orphanet:275864""|panther:PTHR12274(orthology-group)"	mint:A0A5P8YHS1|refseq:WP_002209819.1|interpro:IPR013360(Pilus biogenesis/stability type IV, PilW)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002347816.1|interpro:IPR051012	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/27	rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606	rogid:Cw3Q4dQP076SRhjDt2I5Ae0VRYU632	intact-crc:2F9984CEC92D0D50|rigid:IZi5wM3c1szsRp4CmMAWC97+ACo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P12814	uniprotkb:A0A5P8YHS1	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403.6	intact:EBI-20818378|uniprotkb:Q0WD22|uniprotkb:Q74S82|uniprotkb:Q7CJM8|uniprotkb:A0A0H2W6J0|uniprotkb:A0A384LKH3	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:a0a5p8yhs1_yerpe(display_long)|uniprotkb:YPO2881(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818395|imex:IM-26497-594	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:140957""|ensembl:ENSG00000072110.17(gene)|ensembl:ENST00000193403.11(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007015""(actin filament organization)|go:""GO:0017166""(vinculin binding)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030220""(platelet formation)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031143""(pseudopodium)|go:""GO:0036344""(platelet morphogenesis)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0042995""(cell projection)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051639""(actin filament network formation)|go:""GO:0055001""(muscle cell development)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099186""(structural constituent of postsynapse)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034|refseq:NP_001093.1|refseq:NP_001123476.1|refseq:NP_001123477.1|dip:DIP-33184N|panther:PTHR11915(orthology-group)"	mint:A0A5P8YHS1|refseq:WP_002209819.1|interpro:IPR013360(Pilus biogenesis/stability type IV, PilW)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:YP_002347816.1|interpro:IPR051012	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	rogid:Cw3Q4dQP076SRhjDt2I5Ae0VRYU632	intact-crc:BF953AF3B93CB16C|rigid:b7/32XYhuXMm049PoO2ZAb0TkUA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P21333	uniprotkb:A0A380PIN9	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45|ensembl:ENSP00000358866.3	intact:EBI-20818560|uniprotkb:A0A3G5L991|uniprotkb:A0A2S9PKB5|uniprotkb:Q0W9Y3|uniprotkb:A0A6B3T4U3	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:a0a380pin9_yerpe(display_long)|uniprotkb:YPO4044(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818579|imex:IM-26497-480	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1826""|efo:""Orphanet:2301""|efo:""Orphanet:2484""|efo:""Orphanet:482606""|efo:""Orphanet:555877""|efo:""Orphanet:75497""|efo:""Orphanet:88630""|efo:""Orphanet:90650""|efo:""Orphanet:90652""|efo:""Orphanet:98892""|efo:""Orphanet:99811""|ensembl:ENSG00000196924.19(gene)|ensembl:ENST00000369850.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002102""(podosome)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007195""(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:""GO:0007597""(blood coagulation, intrinsic pathway)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016479""(negative regulation of transcription by RNA polymerase I)|go:""GO:0019900""(kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031523""(Myb complex)|go:""GO:0032233""(positive regulation of actin filament bundle assembly)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043204""(perikaryon)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0044295""(axonal growth cone)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0046332""(SMAD binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050808""(synapse organization)|go:""GO:0050821""(protein stabilization)|go:""GO:0051015""(actin filament binding)|go:""GO:0051020""(GTPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090042""(tubulin deacetylation)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0097368""(establishment of Sertoli cell barrier)|go:""GO:0097440""(apical dendrite)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901381""(positive regulation of potassium ion transmembrane transport)|go:""GO:1902396""(protein localization to bicellular tight junction)|go:""GO:1905000""(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:""GO:1905031""(regulation of membrane repolarization during cardiac muscle cell action potential)|go:""GO:1990779""(glycoprotein Ib-IX-V complex)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|go:""GO:2001224""(positive regulation of neuron migration)|rcsb pdb:6EW1|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|rcsb pdb:7SC4|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|rcsb pdb:7SFT|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|refseq:NP_001104026.1|refseq:NP_001447.2|dip:DIP-1136N|panther:PTHR38537(orthology-group)"	"mint:A0A380PIN9|interpro:IPR050263|refseq:WP_002209597.1|interpro:IPR000259(Fimbrial protein)|interpro:IPR036937|interpro:IPR008966(Adhesion, bacterial)|refseq:YP_002348905.1|panther:PTHR33420(orthology-group)|go:""GO:0009289""(pilus)|go:""GO:0043709""(cell adhesion involved in single-species biofilm formation)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/25	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rogid:TxZIZTi9HZF5P8+cfyPxRyrvDsY632	intact-crc:E859A9C09ED1F1BF|rigid:l3pm/5duUJYK5Iqn4H+ww/6Z82A	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:A0A380PHX5	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20592447|uniprotkb:A0A0H2W9V8|uniprotkb:Q74PA8|uniprotkb:Q7CFN2|uniprotkb:A0A384KIL4	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:a0a380phx5_yerpe(display_long)|uniprotkb:YPO4110(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818597|imex:IM-26497-600	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|refseq:WP_002215571.1|interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|interpro:IPR035906|interpro:IPR043429|panther:PTHR30614(orthology-group)|refseq:YP_002348961.1|mint:A0A380PHX5"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:YPcZDpMnrJjsb3Dz7RiNnm7cFl4632	intact-crc:3BDE90AAD12C287F|rigid:Hxdtu2Lwel9pi6GeQG+xYepr1ew	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UHV2	uniprotkb:P17811	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633.4	intact:EBI-20818652	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:pla_yerpe(display_long)|uniprotkb:pla(gene name)|psi-mi:pla(display_short)|uniprotkb:Coagulase/fibrinolysin(gene name synonym)|uniprotkb:YPPCP1.07(locus name)|uniprotkb:YP_pPCP08(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818674|imex:IM-26497-740	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037508.2|ensembl:ENSG00000197019.5(gene)|ensembl:ENST00000357949.5(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016528""(sarcoplasm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR009263(SERTA)|interpro:IPR052262|mint:Q9UHV2|panther:PTHR16277(orthology-group)"	"mint:P17811|interpro:IPR053724|refseq:NP_395233.1|refseq:NP_857784.1|refseq:WP_002218234.1|refseq:YP_006960975.1|interpro:IPR020080|interpro:IPR020079|interpro:IPR000036(Peptidase A26, omptin)|go:""GO:0004190""(aspartic-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0009279""(cell outer membrane)|rcsb pdb:2X4M|rcsb pdb:2X55|rcsb pdb:2X56|rcsb pdb:4DCB"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:DWXa3kP4mDYakumIOl6Z4qErTBY632	intact-crc:4695DC83A265B9CD|rigid:rHOZiEOkKy0brOOhp0H7wP7QGxk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y228	uniprotkb:A0A380PHX5	intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991.1|ensembl:ENSP00000355992.3	intact:EBI-20592447|uniprotkb:A0A0H2W9V8|uniprotkb:Q74PA8|uniprotkb:Q7CFN2|uniprotkb:A0A384KIL4	psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym)	psi-mi:a0a380phx5_yerpe(display_long)|uniprotkb:YPO4110(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818603|imex:IM-26497-500	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790.15(gene)|ensembl:ENST00000367024.5(transcript)|ensembl:ENST00000367025.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0060090""(molecular adaptor activity)|interpro:IPR051176|mint:Q9Y228|panther:PTHR15715(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|refseq:WP_002215571.1|interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|interpro:IPR035906|interpro:IPR043429|panther:PTHR30614(orthology-group)|refseq:YP_002348961.1|mint:A0A380PHX5"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606	rogid:YPcZDpMnrJjsb3Dz7RiNnm7cFl4632	intact-crc:EDB4F2FED22FDA1E|rigid:5cpY9Rruu67vTi9ku7N2VoFclt4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9HBI0	uniprotkb:Q9S1D9	intact:EBI-3921217|uniprotkb:Q9NSG1|uniprotkb:Q9BQX5|uniprotkb:B4DDW5|uniprotkb:E7EVM6|ensembl:ENSP00000391453.1|ensembl:ENSP00000391583.2	intact:EBI-20818680|uniprotkb:A0A2S9PAX6|uniprotkb:A0A0H2W1U7|uniprotkb:Q74YE4|uniprotkb:A0A380SBF5	psi-mi:parvg_human(display_long)|uniprotkb:PARVG(gene name)|psi-mi:PARVG(display_short)	psi-mi:q9s1d9_yerpe(display_long)|uniprotkb:YPPCP1.08c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818695|imex:IM-26497-780	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001131077.1|refseq:NP_071424.1|refseq:XP_005261759.1|ensembl:ENSG00000138964.18(gene)|ensembl:ENST00000422871.5(transcript)|ensembl:ENST00000444313.8(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0071963""(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI0|panther:PTHR12114(orthology-group)"	"mint:Q9S1D9|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_395234.1|refseq:WP_002213446.1|refseq:YP_006960976.1|interpro:IPR010982(Lambda repressor-like, DNA-binding)|go:""GO:0003677""(DNA binding)"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:s8zEh4PNxhegxr87YnUxAmrb3BE9606	rogid:h9bekaCcofCX6flvtQzs2J7O1zU632	intact-crc:47DF8375F87EB8A6|rigid:YL9WeTWNMg760F4wJ0TlkFPdTek	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBX5	uniprotkb:Q57285	intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008.4	intact:EBI-20818609|uniprotkb:A0A3G5KZ07|uniprotkb:A0A2S9PAX4|uniprotkb:Q7BTY1|uniprotkb:A0A5P8YMD1	psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name)	psi-mi:q57285_yerpe(display_long)|uniprotkb:pim(gene name)|psi-mi:pim(display_short)|uniprotkb:YPPCP1.04(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818634|imex:IM-26497-778	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000140092.16(gene)|ensembl:ENST00000342058.9(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0031012""(extracellular matrix)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046903""(secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000121""(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379|refseq:NP_006320.2|dip:DIP-44301N|efo:""Orphanet:280598""|efo:""Orphanet:90348""|efo:""Orphanet:90349""|panther:PTHR24034(orthology-group)"	mint:Q57285|interpro:IPR031911|refseq:NP_395230.1|refseq:NP_857782.1|refseq:YP_006960972.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/26	rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606	rogid:LBRIOLdlpB56mJ4XoJQi7ZT86v4632	intact-crc:9EFB04B84037B93E|rigid:DKuO0Kfflau2s4DIUM7R761NF4k	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P17980	uniprotkb:Q57285	intact:EBI-359720|uniprotkb:Q3B757|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1|ensembl:ENSP00000298852.3|ensembl:ENSP00000481029.1	intact:EBI-20818609|uniprotkb:A0A3G5KZ07|uniprotkb:A0A2S9PAX4|uniprotkb:Q7BTY1|uniprotkb:A0A5P8YMD1	psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym)	psi-mi:q57285_yerpe(display_long)|uniprotkb:pim(gene name)|psi-mi:pim(display_short)|uniprotkb:YPPCP1.04(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818646|imex:IM-26497-540	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002795.2|ensembl:ENSG00000165916.9(gene)|ensembl:ENST00000298852.8(transcript)|ensembl:ENST00000619920.4(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0000932""(P-body)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043921""(modulation by host of viral transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-27555N|panther:PTHR23073(orthology-group)"	mint:Q57285|interpro:IPR031911|refseq:NP_395230.1|refseq:NP_857782.1|refseq:YP_006960972.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606	rogid:LBRIOLdlpB56mJ4XoJQi7ZT86v4632	intact-crc:E077E1864EFD941A|rigid:QGRIKHVT3OvueImRPpe+ynGW33Y	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q12805	uniprotkb:Q57285	intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|uniprotkb:B4DW75|ensembl:ENSP00000347596.3|ensembl:ENSP00000378058.2	intact:EBI-20818609|uniprotkb:A0A3G5KZ07|uniprotkb:A0A2S9PAX4|uniprotkb:Q7BTY1|uniprotkb:A0A5P8YMD1	psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym)	psi-mi:q57285_yerpe(display_long)|uniprotkb:pim(gene name)|psi-mi:pim(display_short)|uniprotkb:YPPCP1.04(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818622|imex:IM-26497-736	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24039(orthology-group)|ensembl:ENSG00000115380.20(gene)|ensembl:ENST00000355426.8(transcript)|ensembl:ENST00000394555.6(transcript)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007601""(visual perception)|go:""GO:0008083""(growth factor activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0043010""(camera-type eye development)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1|efo:""Orphanet:75376""|efo:""Orphanet:98977"""	mint:Q57285|interpro:IPR031911|refseq:NP_395230.1|refseq:NP_857782.1|refseq:YP_006960972.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606	rogid:LBRIOLdlpB56mJ4XoJQi7ZT86v4632	intact-crc:7C26D273DF83F39B|rigid:fqlbmb1kDL2Ed5SGjEpiDII0a7E	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H0F6	uniprotkb:Q57285	intact:EBI-3942966|uniprotkb:D3DWL3|uniprotkb:Q8IXF5|uniprotkb:Q8IXF6|uniprotkb:A6NEG3|uniprotkb:Q8TB25|uniprotkb:Q9BUE4|uniprotkb:Q8N2E7|uniprotkb:C0L3L2|ensembl:ENSP00000381698.2	intact:EBI-20818609|uniprotkb:A0A3G5KZ07|uniprotkb:A0A2S9PAX4|uniprotkb:Q7BTY1|uniprotkb:A0A5P8YMD1	psi-mi:shrpn_human(display_long)|uniprotkb:SHARPIN(gene name)|psi-mi:SHARPIN(display_short)|uniprotkb:SIPL1(gene name synonym)|uniprotkb:Shank-associated RH domain-interacting protein(gene name synonym)|uniprotkb:Shank-interacting protein-like 1(gene name synonym)|uniprotkb:PSEC0216(orf name)	psi-mi:q57285_yerpe(display_long)|uniprotkb:pim(gene name)|psi-mi:pim(display_short)|uniprotkb:YPPCP1.04(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818628|imex:IM-26497-700	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_112236.3|refseq:XP_016869377.1|dip:DIP-57842N|ensembl:ENSG00000179526.17(gene)|ensembl:ENST00000398712.7(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0030262""(apoptotic nuclear changes)|go:""GO:0030425""(dendrite)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031424""(keratinization)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0071797""(LUBAC complex)|go:""GO:0097039""(protein linear polyubiquitination)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000348""(regulation of CD40 signaling pathway)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR031912|interpro:IPR036443|interpro:IPR051628|mint:Q9H0F6|rcsb pdb:4EMO|rcsb pdb:5X0W|rcsb pdb:8K6P|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-6794361"	mint:Q57285|interpro:IPR031911|refseq:NP_395230.1|refseq:NP_857782.1|refseq:YP_006960972.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/03/26	rogid:+RGl3JO1zsGCdaInDn20yhNZs0E9606	rogid:LBRIOLdlpB56mJ4XoJQi7ZT86v4632	intact-crc:3542C51A672889B1|rigid:JWY+bbbXe2b6tDaQZv7E3ku0iHc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:A0A380PHX5	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20592447|uniprotkb:A0A0H2W9V8|uniprotkb:Q74PA8|uniprotkb:Q7CFN2|uniprotkb:A0A384KIL4	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:a0a380phx5_yerpe(display_long)|uniprotkb:YPO4110(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818591|imex:IM-26497-776	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|refseq:WP_002215571.1|interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|interpro:IPR035906|interpro:IPR043429|panther:PTHR30614(orthology-group)|refseq:YP_002348961.1|mint:A0A380PHX5"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:YPcZDpMnrJjsb3Dz7RiNnm7cFl4632	intact-crc:4C73E0CE21A3D6FA|rigid:3olAYIg4ntCsSw2gqaxTkhTcDZg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O95967	uniprotkb:Q57285	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	intact:EBI-20818609|uniprotkb:A0A3G5KZ07|uniprotkb:A0A2S9PAX4|uniprotkb:Q7BTY1|uniprotkb:A0A5P8YMD1	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:q57285_yerpe(display_long)|uniprotkb:pim(gene name)|psi-mi:pim(display_short)|uniprotkb:YPPCP1.04(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818640|imex:IM-26497-738	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	mint:Q57285|interpro:IPR031911|refseq:NP_395230.1|refseq:NP_857782.1|refseq:YP_006960972.1	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2024/11/14	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:LBRIOLdlpB56mJ4XoJQi7ZT86v4632	intact-crc:2829E2555C7BD788|rigid:zAO28kI7fQdli7MXG9QFwaVErzk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q03252	uniprotkb:A0A380PHX5	intact:EBI-2830427|uniprotkb:O75292|uniprotkb:Q14734|uniprotkb:Q96DF6|intact:EBI-11044751|ensembl:ENSP00000327054.3|intact:EBI-20728818	intact:EBI-20592447|uniprotkb:A0A0H2W9V8|uniprotkb:Q74PA8|uniprotkb:Q7CFN2|uniprotkb:A0A384KIL4	psi-mi:lmnb2_human(display_long)|uniprotkb:LMNB2(gene name)|psi-mi:LMNB2(display_short)|uniprotkb:LMN2(gene name synonym)	psi-mi:a0a380phx5_yerpe(display_long)|uniprotkb:YPO4110(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Yang et al. (2011)	pubmed:21911467|imex:IM-26497|doi:10.1128/IAI.05622-11	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-20818585|imex:IM-26497-640	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:457265""|efo:""Orphanet:79087""|ensembl:ENSG00000176619.13(gene)|ensembl:ENST00000325327.4(transcript)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005882""(intermediate filament)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0090435""(protein localization to nuclear envelope)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:Q03252|rcsb pdb:2LLL|refseq:NP_116126.3|dip:DIP-57724N|panther:PTHR45721(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|refseq:WP_002215571.1|interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|interpro:IPR035906|interpro:IPR043429|panther:PTHR30614(orthology-group)|refseq:YP_002348961.1|mint:A0A380PHX5"	-	-	-	figure legend:ST2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2018/05/04	2025/02/28	rogid:Jt7rEo5Br8HidU+VAc0L6rtBU889606	rogid:YPcZDpMnrJjsb3Dz7RiNnm7cFl4632	intact-crc:822D4259565D2F6E|rigid:wXatKYP6zIWEAC6xJCPHpiq+4lo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q16595	-	intact:EBI-949340|uniprotkb:O15545|uniprotkb:O95656|uniprotkb:Q15294|uniprotkb:Q5VZ01|uniprotkb:A8MXJ6|uniprotkb:C9JJ89|ensembl:ENSP00000419243.2	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:frda_human(display_long)|uniprotkb:Friedreich ataxia protein(gene name synonym)|uniprotkb:FXN(gene name)|psi-mi:FXN(display_short)|uniprotkb:FRDA(gene name synonym)|uniprotkb:X25(gene name synonym)	"psi-mi:""MI:2339""(electron microscopy 3D single particle reconstruction)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21926826|imex:IM-27175-1|emdb:EMD-0560|pdbe:6NZU	intact-miscore:0.49	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"efo:""Orphanet:95""|ensembl:ENSG00000165060.15(gene)|ensembl:ENST00000484259.3(transcript)|go:""GO:0004322""(ferroxidase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007628""(adult walking behavior)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008199""(ferric iron binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009792""(embryo development ending in birth or egg hatching)|go:""GO:0010039""(response to iron ion)|go:""GO:0010722""(regulation of ferrochelatase activity)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0018283""(iron incorporation into metallo-sulfur cluster)|go:""GO:0019230""(proprioception)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0034551""(mitochondrial respiratory chain complex III assembly)|go:""GO:0034986""(iron chaperone activity)|go:""GO:0035265""(organ growth)|go:""GO:0040015""(negative regulation of multicellular organism growth)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043085""(positive regulation of catalytic activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0046621""(negative regulation of organ growth)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0051349""(positive regulation of lyase activity)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1904231""(positive regulation of succinate dehydrogenase activity)|go:""GO:1904234""(positive regulation of aconitate hydratase activity)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|mint:Q16595|rcsb pdb:1EKG|rcsb pdb:1LY7|rcsb pdb:3S4M|rcsb pdb:3S5D|rcsb pdb:3S5E|rcsb pdb:3S5F|rcsb pdb:3T3J|rcsb pdb:3T3K|rcsb pdb:3T3L|rcsb pdb:3T3T|rcsb pdb:3T3X|rcsb pdb:5KZ5|rcsb pdb:6NZU|rcsb pdb:8PK8|rcsb pdb:8PK9|reactome:R-HSA-1268020|reactome:R-HSA-1362409|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_000135.2|refseq:NP_001155178.1|refseq:NP_852090.1|panther:PTHR16821(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 1, Fig. 1a, b, Supplementary Figure 4|3d-resolution:3.2Å|comment:More specifically, the interaction detection method is Cryo-EM with 3D refinement|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:enHzDdgfTff5Y6To5z6k+6rpRMk9606	intact-crc:EBA10576486EEE55	false	binding-associated region:?-?|sufficient binding region:1-74|binding-associated region:37-37	binding-associated region:?-?|sufficient binding region:81-210|binding-associated region:?-?	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q16595	-	intact:EBI-949340|uniprotkb:O15545|uniprotkb:O95656|uniprotkb:Q15294|uniprotkb:Q5VZ01|uniprotkb:A8MXJ6|uniprotkb:C9JJ89|ensembl:ENSP00000419243.2	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:frda_human(display_long)|uniprotkb:Friedreich ataxia protein(gene name synonym)|uniprotkb:FXN(gene name)|psi-mi:FXN(display_short)|uniprotkb:FRDA(gene name synonym)|uniprotkb:X25(gene name synonym)	"psi-mi:""MI:2339""(electron microscopy 3D single particle reconstruction)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21926826|imex:IM-27175-1|emdb:EMD-0560|pdbe:6NZU	intact-miscore:0.49	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"efo:""Orphanet:95""|ensembl:ENSG00000165060.15(gene)|ensembl:ENST00000484259.3(transcript)|go:""GO:0004322""(ferroxidase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007628""(adult walking behavior)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008199""(ferric iron binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009792""(embryo development ending in birth or egg hatching)|go:""GO:0010039""(response to iron ion)|go:""GO:0010722""(regulation of ferrochelatase activity)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0018283""(iron incorporation into metallo-sulfur cluster)|go:""GO:0019230""(proprioception)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0034551""(mitochondrial respiratory chain complex III assembly)|go:""GO:0034986""(iron chaperone activity)|go:""GO:0035265""(organ growth)|go:""GO:0040015""(negative regulation of multicellular organism growth)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043085""(positive regulation of catalytic activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0046621""(negative regulation of organ growth)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0051349""(positive regulation of lyase activity)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1904231""(positive regulation of succinate dehydrogenase activity)|go:""GO:1904234""(positive regulation of aconitate hydratase activity)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|mint:Q16595|rcsb pdb:1EKG|rcsb pdb:1LY7|rcsb pdb:3S4M|rcsb pdb:3S5D|rcsb pdb:3S5E|rcsb pdb:3S5F|rcsb pdb:3T3J|rcsb pdb:3T3K|rcsb pdb:3T3L|rcsb pdb:3T3T|rcsb pdb:3T3X|rcsb pdb:5KZ5|rcsb pdb:6NZU|rcsb pdb:8PK8|rcsb pdb:8PK9|reactome:R-HSA-1268020|reactome:R-HSA-1362409|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_000135.2|refseq:NP_001155178.1|refseq:NP_852090.1|panther:PTHR16821(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 1, Fig. 1a, b, Supplementary Figure 4|3d-resolution:3.2Å|comment:More specifically, the interaction detection method is Cryo-EM with 3D refinement|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:enHzDdgfTff5Y6To5z6k+6rpRMk9606	intact-crc:EBA10576486EEE55	false	binding-associated region:?-?|sufficient binding region:1-74|binding-associated region:37-37	sufficient binding region:81-210|binding-associated region:?-?|binding-associated region:?-?	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9H1K1	-	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623.9	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	"psi-mi:""MI:2339""(electron microscopy 3D single particle reconstruction)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21926826|imex:IM-27175-1|emdb:EMD-0560|pdbe:6NZU	intact-miscore:0.57	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"dip:DIP-39616N|efo:""Orphanet:43115""|ensembl:ENSG00000136003.16(gene)|ensembl:ENST00000311893.14(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1902958""(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:""GO:1904234""(positive regulation of aconitate hydratase activity)|go:""GO:1904439""(negative regulation of iron ion import across plasma membrane)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-9694301|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001306971.1|refseq:NP_055116.1|refseq:NP_998760.1|panther:PTHR10093(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 1, Fig. 1a, b, Supplementary Figure 4|3d-resolution:3.2Å|comment:More specifically, the interaction detection method is Cryo-EM with 3D refinement|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	intact-crc:EBA10576486EEE55	false	binding-associated region:?-?|sufficient binding region:1-74|binding-associated region:37-37	binding-associated region:?-?|sufficient binding region:35-157|binding-associated region:?-?	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9H1K1	-	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623.9	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	"psi-mi:""MI:2339""(electron microscopy 3D single particle reconstruction)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21926826|imex:IM-27175-1|emdb:EMD-0560|pdbe:6NZU	intact-miscore:0.57	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"dip:DIP-39616N|efo:""Orphanet:43115""|ensembl:ENSG00000136003.16(gene)|ensembl:ENST00000311893.14(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1902958""(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:""GO:1904234""(positive regulation of aconitate hydratase activity)|go:""GO:1904439""(negative regulation of iron ion import across plasma membrane)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-9694301|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001306971.1|refseq:NP_055116.1|refseq:NP_998760.1|panther:PTHR10093(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 1, Fig. 1a, b, Supplementary Figure 4|3d-resolution:3.2Å|comment:More specifically, the interaction detection method is Cryo-EM with 3D refinement|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	intact-crc:EBA10576486EEE55	false	binding-associated region:?-?|sufficient binding region:1-74|binding-associated region:37-37	sufficient binding region:35-157|binding-associated region:?-?|binding-associated region:?-?	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9HD34	-	intact:EBI-3920810|uniprotkb:A8K543|uniprotkb:Q5XKP1|ensembl:ENSP00000418787.1	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:lyrm4_human(display_long)|uniprotkb:LYRM4(gene name)|psi-mi:LYRM4(display_short)|uniprotkb:C6orf149(gene name synonym)|uniprotkb:ISD11(gene name synonym)|uniprotkb:CGI-203(orf name)	"psi-mi:""MI:2339""(electron microscopy 3D single particle reconstruction)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21926826|imex:IM-27175-1|emdb:EMD-0560|pdbe:6NZU	intact-miscore:0.49	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"ensembl:ENSG00000214113.11(gene)|ensembl:ENST00000330636.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0016604""(nuclear body)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1990221""(L-cysteine desulfurase complex)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR045297|interpro:IPR051522|mint:Q9HD34|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6ODD|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001158313.1|refseq:NP_065141.3|efo:""Orphanet:397593""|panther:PTHR13166(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 1, Fig. 1a, b, Supplementary Figure 4|3d-resolution:3.2Å|comment:More specifically, the interaction detection method is Cryo-EM with 3D refinement|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:42Smt00XZS1ZIumThh+hX/ARM7M9606	intact-crc:EBA10576486EEE55	false	binding-associated region:?-?|sufficient binding region:1-74|binding-associated region:37-37	binding-associated region:?-?|sufficient binding region:1-91|his tag:?-?|binding-associated region:?-?	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9HD34	-	intact:EBI-3920810|uniprotkb:A8K543|uniprotkb:Q5XKP1|ensembl:ENSP00000418787.1	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:lyrm4_human(display_long)|uniprotkb:LYRM4(gene name)|psi-mi:LYRM4(display_short)|uniprotkb:C6orf149(gene name synonym)|uniprotkb:ISD11(gene name synonym)|uniprotkb:CGI-203(orf name)	"psi-mi:""MI:2339""(electron microscopy 3D single particle reconstruction)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21926826|imex:IM-27175-1|emdb:EMD-0560|pdbe:6NZU	intact-miscore:0.49	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"ensembl:ENSG00000214113.11(gene)|ensembl:ENST00000330636.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0016604""(nuclear body)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1990221""(L-cysteine desulfurase complex)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR045297|interpro:IPR051522|mint:Q9HD34|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6ODD|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001158313.1|refseq:NP_065141.3|efo:""Orphanet:397593""|panther:PTHR13166(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 1, Fig. 1a, b, Supplementary Figure 4|3d-resolution:3.2Å|comment:More specifically, the interaction detection method is Cryo-EM with 3D refinement|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:42Smt00XZS1ZIumThh+hX/ARM7M9606	intact-crc:EBA10576486EEE55	false	binding-associated region:?-?|sufficient binding region:1-74|binding-associated region:37-37	his tag:?-?|sufficient binding region:1-91|binding-associated region:?-?|binding-associated region:?-?	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9Y697-2	-	intact:EBI-10962075|ensembl:ENSP00000363198.1|ensembl:ENSP00000380570.1	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:q9y697-2(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:NIFS(gene name synonym)|uniprotkb:HUSSY-08(orf name)	"psi-mi:""MI:2339""(electron microscopy 3D single particle reconstruction)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21926826|imex:IM-27175-1|emdb:EMD-0560|pdbe:6NZU	intact-miscore:0.32	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	intact:EBI-1751791(isoform-parent)|uniprotkb:Q9Y697-2(isoform-parent)|ensembl:ENSG00000244005.13(gene)|ensembl:ENST00000374085.5(transcript)|ensembl:ENST00000397425.5(transcript)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 1, Fig. 1a, b, Supplementary Figure 4|3d-resolution:3.2Å|comment:More specifically, the interaction detection method is Cryo-EM with 3D refinement|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:uDJY7pQiWR7uKc3pax0jWAGPCcw9606	intact-crc:EBA10576486EEE55	false	binding-associated region:?-?|sufficient binding region:1-74|binding-associated region:37-37	sufficient binding region:1-397|binding-associated region:198-198|binding-associated region:?-?|binding-associated region:?-?|binding-associated region:?-?	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9Y697-2	-	intact:EBI-10962075|ensembl:ENSP00000363198.1|ensembl:ENSP00000380570.1	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:q9y697-2(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:NIFS(gene name synonym)|uniprotkb:HUSSY-08(orf name)	"psi-mi:""MI:2339""(electron microscopy 3D single particle reconstruction)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21926826|imex:IM-27175-1|emdb:EMD-0560|pdbe:6NZU	intact-miscore:0.32	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	intact:EBI-1751791(isoform-parent)|uniprotkb:Q9Y697-2(isoform-parent)|ensembl:ENSG00000244005.13(gene)|ensembl:ENST00000374085.5(transcript)|ensembl:ENST00000397425.5(transcript)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 1, Fig. 1a, b, Supplementary Figure 4|3d-resolution:3.2Å|comment:More specifically, the interaction detection method is Cryo-EM with 3D refinement|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:uDJY7pQiWR7uKc3pax0jWAGPCcw9606	intact-crc:EBA10576486EEE55	false	binding-associated region:?-?|sufficient binding region:1-74|binding-associated region:37-37	sufficient binding region:1-397|binding-associated region:198-198|binding-associated region:?-?|binding-associated region:?-?|binding-associated region:?-?	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H1K1	intact:EBI-21926813	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623.9	-	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21926930|imex:IM-27175-3	intact-miscore:0.57	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-39616N|efo:""Orphanet:43115""|ensembl:ENSG00000136003.16(gene)|ensembl:ENST00000311893.14(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1902958""(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:""GO:1904234""(positive regulation of aconitate hydratase activity)|go:""GO:1904439""(negative regulation of iron ion import across plasma membrane)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-9694301|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001306971.1|refseq:NP_055116.1|refseq:NP_998760.1|panther:PTHR10093(orthology-group)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	"figure legend:Table 1, Supplementary Figure 1d|caution:""\""Impact of FXN mutations is on the whole of SDAU complex (NFS1-ISD11-ACP-ISCU); SDAU is not a functional complex without FXN so we couldn't have the possibility of generating a complex portal identifier so as to be taken as a participant\""""|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease"	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.32x10^-6 ~0.94(molar)	2019/07/19	2025/01/28	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	intact-crc:673E20A18D030FDC|rigid:e86O6aqYqrYSam4/t/UJBT97f3M	false	sufficient binding region:35-167|biotin tag:?-?	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q16595	-	intact:EBI-949340|uniprotkb:O15545|uniprotkb:O95656|uniprotkb:Q15294|uniprotkb:Q5VZ01|uniprotkb:A8MXJ6|uniprotkb:C9JJ89|ensembl:ENSP00000419243.2	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:frda_human(display_long)|uniprotkb:Friedreich ataxia protein(gene name synonym)|uniprotkb:FXN(gene name)|psi-mi:FXN(display_short)|uniprotkb:FRDA(gene name synonym)|uniprotkb:X25(gene name synonym)	"psi-mi:""MI:0826""(x ray scattering)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21942347|imex:IM-27175-7	intact-miscore:0.49	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"efo:""Orphanet:95""|ensembl:ENSG00000165060.15(gene)|ensembl:ENST00000484259.3(transcript)|go:""GO:0004322""(ferroxidase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007628""(adult walking behavior)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008199""(ferric iron binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009792""(embryo development ending in birth or egg hatching)|go:""GO:0010039""(response to iron ion)|go:""GO:0010722""(regulation of ferrochelatase activity)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0018283""(iron incorporation into metallo-sulfur cluster)|go:""GO:0019230""(proprioception)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0034551""(mitochondrial respiratory chain complex III assembly)|go:""GO:0034986""(iron chaperone activity)|go:""GO:0035265""(organ growth)|go:""GO:0040015""(negative regulation of multicellular organism growth)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043085""(positive regulation of catalytic activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0046621""(negative regulation of organ growth)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0051349""(positive regulation of lyase activity)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1904231""(positive regulation of succinate dehydrogenase activity)|go:""GO:1904234""(positive regulation of aconitate hydratase activity)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|mint:Q16595|rcsb pdb:1EKG|rcsb pdb:1LY7|rcsb pdb:3S4M|rcsb pdb:3S5D|rcsb pdb:3S5E|rcsb pdb:3S5F|rcsb pdb:3T3J|rcsb pdb:3T3K|rcsb pdb:3T3L|rcsb pdb:3T3T|rcsb pdb:3T3X|rcsb pdb:5KZ5|rcsb pdb:6NZU|rcsb pdb:8PK8|rcsb pdb:8PK9|reactome:R-HSA-1268020|reactome:R-HSA-1362409|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_000135.2|refseq:NP_001155178.1|refseq:NP_852090.1|panther:PTHR16821(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 4, Supplementary Figure 7|3d-resolution:0.99 Å|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:enHzDdgfTff5Y6To5z6k+6rpRMk9606	intact-crc:B8FA86C090832D55	false	sufficient binding region:1-74	sufficient binding region:81-210	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9H1K1	-	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623.9	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	"psi-mi:""MI:0826""(x ray scattering)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21942347|imex:IM-27175-7	intact-miscore:0.57	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"dip:DIP-39616N|efo:""Orphanet:43115""|ensembl:ENSG00000136003.16(gene)|ensembl:ENST00000311893.14(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1902958""(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:""GO:1904234""(positive regulation of aconitate hydratase activity)|go:""GO:1904439""(negative regulation of iron ion import across plasma membrane)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-9694301|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001306971.1|refseq:NP_055116.1|refseq:NP_998760.1|panther:PTHR10093(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 4, Supplementary Figure 7|3d-resolution:0.99 Å|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	intact-crc:B8FA86C090832D55	false	sufficient binding region:1-74	sufficient binding region:35-157	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9HD34	-	intact:EBI-3920810|uniprotkb:A8K543|uniprotkb:Q5XKP1|ensembl:ENSP00000418787.1	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:lyrm4_human(display_long)|uniprotkb:LYRM4(gene name)|psi-mi:LYRM4(display_short)|uniprotkb:C6orf149(gene name synonym)|uniprotkb:ISD11(gene name synonym)|uniprotkb:CGI-203(orf name)	"psi-mi:""MI:0826""(x ray scattering)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21942347|imex:IM-27175-7	intact-miscore:0.49	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"ensembl:ENSG00000214113.11(gene)|ensembl:ENST00000330636.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0016604""(nuclear body)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1990221""(L-cysteine desulfurase complex)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR045297|interpro:IPR051522|mint:Q9HD34|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6ODD|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001158313.1|refseq:NP_065141.3|efo:""Orphanet:397593""|panther:PTHR13166(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 4, Supplementary Figure 7|3d-resolution:0.99 Å|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:42Smt00XZS1ZIumThh+hX/ARM7M9606	intact-crc:B8FA86C090832D55	false	sufficient binding region:1-74	his tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9Y697	-	intact:EBI-1751791|uniprotkb:E1P5R8|uniprotkb:Q6P0L8|uniprotkb:Q9NTZ5|uniprotkb:Q9Y481|uniprotkb:B3KMA5|uniprotkb:B4DXK9|uniprotkb:F5GYK5|ensembl:ENSP00000363205.3	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:nfs1_human(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:NIFS(gene name synonym)|uniprotkb:HUSSY-08(orf name)	"psi-mi:""MI:0826""(x ray scattering)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21942347|imex:IM-27175-7	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"ensembl:ENSG00000244005.13(gene)|ensembl:ENST00000374092.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006777""(Mo-molybdopterin cofactor biosynthetic process)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0018283""(iron incorporation into metallo-sulfur cluster)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0031071""(cysteine desulfurase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043545""(molybdopterin cofactor metabolic process)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0051536""(iron-sulfur cluster binding)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR016454(Cysteine desulphurase, NifS)|interpro:IPR020578|mint:Q9Y697|rcsb pdb:5KZ5|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-947581|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001185918.1|refseq:NP_066923.3|efo:""Orphanet:397593""|panther:PTHR11601(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 4, Supplementary Figure 7|3d-resolution:0.99 Å|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:tSeWDc9Ch78CnCC2Co+vzC2CWvg9606	intact-crc:B8FA86C090832D55	false	sufficient binding region:1-74	sufficient binding region:56-457	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9H1K1	-	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623.9	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	"psi-mi:""MI:0826""(x ray scattering)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21942391|imex:IM-27175-9	intact-miscore:0.57	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"dip:DIP-39616N|efo:""Orphanet:43115""|ensembl:ENSG00000136003.16(gene)|ensembl:ENST00000311893.14(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1902958""(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:""GO:1904234""(positive regulation of aconitate hydratase activity)|go:""GO:1904439""(negative regulation of iron ion import across plasma membrane)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-9694301|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001306971.1|refseq:NP_055116.1|refseq:NP_998760.1|panther:PTHR10093(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 4, Supplementary Figure 7|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	intact-crc:14DC7A80C5A80C82	false	sufficient binding region:1-74	sufficient binding region:35-157	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9HD34	-	intact:EBI-3920810|uniprotkb:A8K543|uniprotkb:Q5XKP1|ensembl:ENSP00000418787.1	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:lyrm4_human(display_long)|uniprotkb:LYRM4(gene name)|psi-mi:LYRM4(display_short)|uniprotkb:C6orf149(gene name synonym)|uniprotkb:ISD11(gene name synonym)|uniprotkb:CGI-203(orf name)	"psi-mi:""MI:0826""(x ray scattering)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21942391|imex:IM-27175-9	intact-miscore:0.49	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"ensembl:ENSG00000214113.11(gene)|ensembl:ENST00000330636.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0016604""(nuclear body)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1990221""(L-cysteine desulfurase complex)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR045297|interpro:IPR051522|mint:Q9HD34|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6ODD|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001158313.1|refseq:NP_065141.3|efo:""Orphanet:397593""|panther:PTHR13166(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 4, Supplementary Figure 7|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:42Smt00XZS1ZIumThh+hX/ARM7M9606	intact-crc:14DC7A80C5A80C82	false	sufficient binding region:1-74	his tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-21926813	uniprotkb:Q9Y697	-	intact:EBI-1751791|uniprotkb:E1P5R8|uniprotkb:Q6P0L8|uniprotkb:Q9NTZ5|uniprotkb:Q9Y481|uniprotkb:B3KMA5|uniprotkb:B4DXK9|uniprotkb:F5GYK5|ensembl:ENSP00000363205.3	psi-mi:a0a437hbf4_ecolx(display_short)|psi-mi:EBI-21926813(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:DQL48_09575(orf name)	psi-mi:nfs1_human(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:NIFS(gene name synonym)|uniprotkb:HUSSY-08(orf name)	"psi-mi:""MI:0826""(x ray scattering)"	Fox et al. (2019)	pubmed:31101807|imex:IM-27175	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-21942391|imex:IM-27175-9	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A437HBF4(uniprot-removed-ac)	"ensembl:ENSG00000244005.13(gene)|ensembl:ENST00000374092.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006777""(Mo-molybdopterin cofactor biosynthetic process)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0018283""(iron incorporation into metallo-sulfur cluster)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0031071""(cysteine desulfurase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043545""(molybdopterin cofactor metabolic process)|go:""GO:0044571""([2Fe-2S] cluster assembly)|go:""GO:0044572""([4Fe-4S] cluster assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0051536""(iron-sulfur cluster binding)|go:""GO:0099128""(mitochondrial [2Fe-2S] assembly complex)|go:""GO:1990229""(iron-sulfur cluster assembly complex)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR016454(Cysteine desulphurase, NifS)|interpro:IPR020578|mint:Q9Y697|rcsb pdb:5KZ5|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|rcsb pdb:7RTK|rcsb pdb:8PK8|rcsb pdb:8PK9|rcsb pdb:8PKA|rcsb pdb:8TVT|reactome:R-HSA-1362409|reactome:R-HSA-947581|reactome:R-HSA-9854311|reactome:R-HSA-9865881|refseq:NP_001185918.1|refseq:NP_066923.3|efo:""Orphanet:397593""|panther:PTHR11601(orthology-group)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Supplementary Table 4, Supplementary Figure 7|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/19	2025/01/28	rogid:QLE13yoHfia69IvwhdD61xR/Ejw562	rogid:tSeWDc9Ch78CnCC2Co+vzC2CWvg9606	intact-crc:14DC7A80C5A80C82	false	sufficient binding region:1-74	sufficient binding region:56-457	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P18177	uniprotkb:P63000	intact:EBI-8536569|uniprotkb:M4NW36|intact:MINT-2634250	intact:EBI-413628|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q9BTB4|uniprotkb:Q5JAA8|ensembl:ENSP00000258737.7	psi-mi:tcdb_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Genth et al. (2006)	mint:MINT-5218701|pubmed:16730714|imex:IM-10937	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0559""(glycosylation reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8536562|mint:MINT-2634266|imex:IM-10937-1	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046527""(glucosyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|rcsb pdb:2BVL|rcsb pdb:2BVM|rcsb pdb:4NC2|rcsb pdb:4NP4|rcsb pdb:5UQM|rcsb pdb:5UQN|rcsb pdb:5UQT|rcsb pdb:6AR6|rcsb pdb:6C0B|rcsb pdb:6OQ5|rcsb pdb:6OQ6|rcsb pdb:6OQ7|rcsb pdb:6OQ8|rcsb pdb:7LOU|rcsb pdb:7LOV|rcsb pdb:7ML7|rcsb pdb:7N8X|rcsb pdb:7N95|rcsb pdb:7N97|rcsb pdb:7N9Q|rcsb pdb:7N9R|rcsb pdb:7N9S|rcsb pdb:7N9Y|rcsb pdb:7S0Y|rcsb pdb:7SO5|rcsb pdb:7SO7|rcsb pdb:8QEN|rcsb pdb:8QEO|rcsb pdb:8Y9B|rcsb pdb:9BJA|refseq:WP_009902069.1|interpro:IPR024770|interpro:IPR020974|interpro:IPR018337|interpro:IPR024772|interpro:IPR024769|interpro:IPR029044|interpro:IPR038383|mint:P18177|mint:MINT-2634268(identity)"	"efo:""Orphanet:500159""|ensembl:ENSG00000136238.20(gene)|ensembl:ENST00000348035.9(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006954""(inflammatory response)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009611""(response to wounding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031529""(ruffle organization)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032707""(negative regulation of interleukin-23 production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042470""(melanosome)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045428""(regulation of nitric oxide biosynthetic process)|go:""GO:0045730""(respiratory burst)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048870""(cell motility)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051668""(localization within membrane)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060263""(regulation of respiratory burst)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0097178""(ruffle assembly)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902622""(regulation of neutrophil migration)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:7DPA|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|rcsb pdb:7SJ4|rcsb pdb:7USD|rcsb pdb:7USE|rcsb pdb:8I5V|rcsb pdb:8I5W|rcsb pdb:8Q0N|rcsb pdb:8WEJ|rcsb pdb:8ZJ2|rcsb pdb:8ZJI|rcsb pdb:8ZJJ|rcsb pdb:8ZJK|rcsb pdb:8ZJL|rcsb pdb:8ZJM|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-9748787|reactome:R-HSA-983231|refseq:NP_008839.2|refseq:NP_061485.1|dip:DIP-29260N|panther:PTHR24072(orthology-group)|ensembl:ENSP00000258737.7|ensembl:ENST00000356142.4|ensembl:ENSP00000348461.4|mint:MINT-2634267(identity)"	-	"comment:mint|function:Cytotoxin|comment:""\""Stoichiometry: 1.0\"""""	"comment:""\""Stoichiometry: 1.0\"""""	figure legend:F4|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/06/21	2024/11/14	rogid:K4BbX+DMm7uUt0CrM1ONCFqaPwc1496	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:38920DF52BD09480|rigid:qRTjd63f1Fg40szAqix4aetLz3k	false	-	-	1	1	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UI95	uniprotkb:P18011	intact:EBI-77889|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3|ensembl:ENSP00000235310.2|ensembl:ENSP00000365855.3|ensembl:ENSP00000365882.4|ensembl:ENSP00000400982.2	intact:EBI-490239	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	psi-mi:scte_shifl(display_long)|uniprotkb:sctE(gene name)|psi-mi:sctE(display_short)|uniprotkb:62 kDa antigen(gene name synonym)|uniprotkb:Invasin IpaB(gene name synonym)|uniprotkb:ipaB(gene name synonym)|uniprotkb:CP0128(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Iwai et al. (2007)	imex:IM-11936|pubmed:17719540	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1535589|imex:IM-11936-15	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11842(orthology-group)|efo:""Orphanet:84""|ensembl:ENSG00000116670.17(gene)|ensembl:ENST00000235310.7(transcript)|ensembl:ENST00000376667.7(transcript)|ensembl:ENST00000376692.9(transcript)|ensembl:ENST00000456915.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002208""(somatic diversification of immunoglobulins involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006302""(double-strand break repair)|go:""GO:0007015""(actin filament organization)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|rcsb pdb:6WS0|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016035""(zeta DNA polymerase complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0042772""(DNA damage response, signal transduction resulting in transcription)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051301""(cell division)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000678""(negative regulation of transcription regulatory region DNA binding)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|interpro:IPR045091|mint:Q9UI95|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0042025""(host cell nucleus)|go:""GO:0043657""(host cell)|interpro:IPR003895(Salmonella/Shigella invasin protein B)|interpro:IPR006972(""Secretion system effector C (SseC) like protein"")|interpro:IPR032391|rcsb pdb:3GZ1|rcsb pdb:3GZ2|rcsb pdb:3U0C|rcsb pdb:5WKQ|rcsb pdb:6KEA|refseq:NP_858261.1|refseq:NP_085290.1|refseq:YP_009062485.1|refseq:WP_010921663.1|dip:DIP-45233N"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2007/09/21	2024/11/06	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	rogid:+VZIF6Bf6eIW6pUUylqTLn/yfW4623	intact-crc:D1893923B691ED9F|rigid:6ksXe3KkoTwXoxUU++/PBiB3/3A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UI95	uniprotkb:P18011	intact:EBI-77889|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3|ensembl:ENSP00000235310.2|ensembl:ENSP00000365855.3|ensembl:ENSP00000365882.4|ensembl:ENSP00000400982.2	intact:EBI-490239	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	psi-mi:scte_shifl(display_long)|uniprotkb:sctE(gene name)|psi-mi:sctE(display_short)|uniprotkb:62 kDa antigen(gene name synonym)|uniprotkb:Invasin IpaB(gene name synonym)|uniprotkb:ipaB(gene name synonym)|uniprotkb:CP0128(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Iwai et al. (2007)	imex:IM-11936|pubmed:17719540	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1535600|imex:IM-11936-1	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11842(orthology-group)|efo:""Orphanet:84""|ensembl:ENSG00000116670.17(gene)|ensembl:ENST00000235310.7(transcript)|ensembl:ENST00000376667.7(transcript)|ensembl:ENST00000376692.9(transcript)|ensembl:ENST00000456915.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002208""(somatic diversification of immunoglobulins involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006302""(double-strand break repair)|go:""GO:0007015""(actin filament organization)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|rcsb pdb:6WS0|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016035""(zeta DNA polymerase complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0042772""(DNA damage response, signal transduction resulting in transcription)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051301""(cell division)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000678""(negative regulation of transcription regulatory region DNA binding)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|interpro:IPR045091|mint:Q9UI95|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0042025""(host cell nucleus)|go:""GO:0043657""(host cell)|interpro:IPR003895(Salmonella/Shigella invasin protein B)|interpro:IPR006972(""Secretion system effector C (SseC) like protein"")|interpro:IPR032391|rcsb pdb:3GZ1|rcsb pdb:3GZ2|rcsb pdb:3U0C|rcsb pdb:5WKQ|rcsb pdb:6KEA|refseq:NP_858261.1|refseq:NP_085290.1|refseq:YP_009062485.1|refseq:WP_010921663.1|dip:DIP-45233N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:1A & Supp S5A & 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2007/09/21	2024/11/06	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	rogid:+VZIF6Bf6eIW6pUUylqTLn/yfW4623	intact-crc:8D0D795C27315B7F|rigid:6ksXe3KkoTwXoxUU++/PBiB3/3A	false	-	necessary binding region:61-70	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P18011	uniprotkb:Q9UI95	intact:EBI-490239	intact:EBI-77889|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3|ensembl:ENSP00000235310.2|ensembl:ENSP00000365855.3|ensembl:ENSP00000365882.4|ensembl:ENSP00000400982.2	psi-mi:scte_shifl(display_long)|uniprotkb:sctE(gene name)|psi-mi:sctE(display_short)|uniprotkb:62 kDa antigen(gene name synonym)|uniprotkb:Invasin IpaB(gene name synonym)|uniprotkb:ipaB(gene name synonym)|uniprotkb:CP0128(locus name)	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Iwai et al. (2007)	imex:IM-11936|pubmed:17719540	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1535647|imex:IM-11936-11	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0042025""(host cell nucleus)|go:""GO:0043657""(host cell)|interpro:IPR003895(Salmonella/Shigella invasin protein B)|interpro:IPR006972(""Secretion system effector C (SseC) like protein"")|interpro:IPR032391|rcsb pdb:3GZ1|rcsb pdb:3GZ2|rcsb pdb:3U0C|rcsb pdb:5WKQ|rcsb pdb:6KEA|refseq:NP_858261.1|refseq:NP_085290.1|refseq:YP_009062485.1|refseq:WP_010921663.1|dip:DIP-45233N"	"panther:PTHR11842(orthology-group)|efo:""Orphanet:84""|ensembl:ENSG00000116670.17(gene)|ensembl:ENST00000235310.7(transcript)|ensembl:ENST00000376667.7(transcript)|ensembl:ENST00000376692.9(transcript)|ensembl:ENST00000456915.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002208""(somatic diversification of immunoglobulins involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006302""(double-strand break repair)|go:""GO:0007015""(actin filament organization)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|rcsb pdb:6WS0|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016035""(zeta DNA polymerase complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0042772""(DNA damage response, signal transduction resulting in transcription)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051301""(cell division)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000678""(negative regulation of transcription regulatory region DNA binding)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|interpro:IPR045091|mint:Q9UI95|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/21	2024/11/06	rogid:+VZIF6Bf6eIW6pUUylqTLn/yfW4623	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	intact-crc:5DDD50CBE550D1B8|rigid:6ksXe3KkoTwXoxUU++/PBiB3/3A	false	-	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q9UI95	uniprotkb:P18011	intact:EBI-77889|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3|ensembl:ENSP00000235310.2|ensembl:ENSP00000365855.3|ensembl:ENSP00000365882.4|ensembl:ENSP00000400982.2	intact:EBI-490239	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	psi-mi:scte_shifl(display_long)|uniprotkb:sctE(gene name)|psi-mi:sctE(display_short)|uniprotkb:62 kDa antigen(gene name synonym)|uniprotkb:Invasin IpaB(gene name synonym)|uniprotkb:ipaB(gene name synonym)|uniprotkb:CP0128(locus name)	"psi-mi:""MI:0096""(pull down)"	Iwai et al. (2007)	imex:IM-11936|pubmed:17719540	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1535660|imex:IM-11936-12	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11842(orthology-group)|efo:""Orphanet:84""|ensembl:ENSG00000116670.17(gene)|ensembl:ENST00000235310.7(transcript)|ensembl:ENST00000376667.7(transcript)|ensembl:ENST00000376692.9(transcript)|ensembl:ENST00000456915.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002208""(somatic diversification of immunoglobulins involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006302""(double-strand break repair)|go:""GO:0007015""(actin filament organization)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|rcsb pdb:6WS0|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016035""(zeta DNA polymerase complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0042772""(DNA damage response, signal transduction resulting in transcription)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051301""(cell division)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000678""(negative regulation of transcription regulatory region DNA binding)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|interpro:IPR045091|mint:Q9UI95|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0042025""(host cell nucleus)|go:""GO:0043657""(host cell)|interpro:IPR003895(Salmonella/Shigella invasin protein B)|interpro:IPR006972(""Secretion system effector C (SseC) like protein"")|interpro:IPR032391|rcsb pdb:3GZ1|rcsb pdb:3GZ2|rcsb pdb:3U0C|rcsb pdb:5WKQ|rcsb pdb:6KEA|refseq:NP_858261.1|refseq:NP_085290.1|refseq:YP_009062485.1|refseq:WP_010921663.1|dip:DIP-45233N"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/21	2024/11/06	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	rogid:+VZIF6Bf6eIW6pUUylqTLn/yfW4623	intact-crc:BCDA4454866D023F|rigid:6ksXe3KkoTwXoxUU++/PBiB3/3A	false	maltose binding protein tag:?-?	sufficient binding region:1-312	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q9UI95	uniprotkb:P18011	intact:EBI-77889|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3|ensembl:ENSP00000235310.2|ensembl:ENSP00000365855.3|ensembl:ENSP00000365882.4|ensembl:ENSP00000400982.2	intact:EBI-490239	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	psi-mi:scte_shifl(display_long)|uniprotkb:sctE(gene name)|psi-mi:sctE(display_short)|uniprotkb:62 kDa antigen(gene name synonym)|uniprotkb:Invasin IpaB(gene name synonym)|uniprotkb:ipaB(gene name synonym)|uniprotkb:CP0128(locus name)	"psi-mi:""MI:0096""(pull down)"	Iwai et al. (2007)	imex:IM-11936|pubmed:17719540	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1536022|imex:IM-11936-13	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11842(orthology-group)|efo:""Orphanet:84""|ensembl:ENSG00000116670.17(gene)|ensembl:ENST00000235310.7(transcript)|ensembl:ENST00000376667.7(transcript)|ensembl:ENST00000376692.9(transcript)|ensembl:ENST00000456915.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002208""(somatic diversification of immunoglobulins involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006302""(double-strand break repair)|go:""GO:0007015""(actin filament organization)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|rcsb pdb:6WS0|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016035""(zeta DNA polymerase complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0042772""(DNA damage response, signal transduction resulting in transcription)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051301""(cell division)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000678""(negative regulation of transcription regulatory region DNA binding)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|interpro:IPR045091|mint:Q9UI95|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0042025""(host cell nucleus)|go:""GO:0043657""(host cell)|interpro:IPR003895(Salmonella/Shigella invasin protein B)|interpro:IPR006972(""Secretion system effector C (SseC) like protein"")|interpro:IPR032391|rcsb pdb:3GZ1|rcsb pdb:3GZ2|rcsb pdb:3U0C|rcsb pdb:5WKQ|rcsb pdb:6KEA|refseq:NP_858261.1|refseq:NP_085290.1|refseq:YP_009062485.1|refseq:WP_010921663.1|dip:DIP-45233N"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	figure legend:1B, Supp 5C and Supp 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/21	2024/11/06	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	rogid:+VZIF6Bf6eIW6pUUylqTLn/yfW4623	intact-crc:C5655E8DF6C92028|rigid:6ksXe3KkoTwXoxUU++/PBiB3/3A	false	maltose binding protein tag:?-?|sufficient binding region:150-211	sufficient binding region:1-312|mutation decreasing interaction:61-61	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q9UI95	uniprotkb:P18011	intact:EBI-77889|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3|ensembl:ENSP00000235310.2|ensembl:ENSP00000365855.3|ensembl:ENSP00000365882.4|ensembl:ENSP00000400982.2	intact:EBI-490239	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	psi-mi:scte_shifl(display_long)|uniprotkb:sctE(gene name)|psi-mi:sctE(display_short)|uniprotkb:62 kDa antigen(gene name synonym)|uniprotkb:Invasin IpaB(gene name synonym)|uniprotkb:ipaB(gene name synonym)|uniprotkb:CP0128(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Iwai et al. (2007)	imex:IM-11936|pubmed:17719540	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1535693|imex:IM-11936-3	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11842(orthology-group)|efo:""Orphanet:84""|ensembl:ENSG00000116670.17(gene)|ensembl:ENST00000235310.7(transcript)|ensembl:ENST00000376667.7(transcript)|ensembl:ENST00000376692.9(transcript)|ensembl:ENST00000456915.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002208""(somatic diversification of immunoglobulins involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006302""(double-strand break repair)|go:""GO:0007015""(actin filament organization)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|rcsb pdb:6WS0|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016035""(zeta DNA polymerase complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0042772""(DNA damage response, signal transduction resulting in transcription)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051301""(cell division)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000678""(negative regulation of transcription regulatory region DNA binding)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|interpro:IPR045091|mint:Q9UI95|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0042025""(host cell nucleus)|go:""GO:0043657""(host cell)|interpro:IPR003895(Salmonella/Shigella invasin protein B)|interpro:IPR006972(""Secretion system effector C (SseC) like protein"")|interpro:IPR032391|rcsb pdb:3GZ1|rcsb pdb:3GZ2|rcsb pdb:3U0C|rcsb pdb:5WKQ|rcsb pdb:6KEA|refseq:NP_858261.1|refseq:NP_085290.1|refseq:YP_009062485.1|refseq:WP_010921663.1|dip:DIP-45233N"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2007/09/21	2024/11/06	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	rogid:+VZIF6Bf6eIW6pUUylqTLn/yfW4623	intact-crc:0226F87E96D22BA5|rigid:6ksXe3KkoTwXoxUU++/PBiB3/3A	false	-	flag tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q9UI95	uniprotkb:P18011	intact:EBI-77889|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3|ensembl:ENSP00000235310.2|ensembl:ENSP00000365855.3|ensembl:ENSP00000365882.4|ensembl:ENSP00000400982.2	intact:EBI-490239	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	psi-mi:scte_shifl(display_long)|uniprotkb:sctE(gene name)|psi-mi:sctE(display_short)|uniprotkb:62 kDa antigen(gene name synonym)|uniprotkb:Invasin IpaB(gene name synonym)|uniprotkb:ipaB(gene name synonym)|uniprotkb:CP0128(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Iwai et al. (2007)	imex:IM-11936|pubmed:17719540	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1535754|imex:IM-11936-14	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11842(orthology-group)|efo:""Orphanet:84""|ensembl:ENSG00000116670.17(gene)|ensembl:ENST00000235310.7(transcript)|ensembl:ENST00000376667.7(transcript)|ensembl:ENST00000376692.9(transcript)|ensembl:ENST00000456915.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002208""(somatic diversification of immunoglobulins involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006302""(double-strand break repair)|go:""GO:0007015""(actin filament organization)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|rcsb pdb:6WS0|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016035""(zeta DNA polymerase complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0042772""(DNA damage response, signal transduction resulting in transcription)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051301""(cell division)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000678""(negative regulation of transcription regulatory region DNA binding)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|interpro:IPR045091|mint:Q9UI95|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0033644""(host cell membrane)|go:""GO:0042025""(host cell nucleus)|go:""GO:0043657""(host cell)|interpro:IPR003895(Salmonella/Shigella invasin protein B)|interpro:IPR006972(""Secretion system effector C (SseC) like protein"")|interpro:IPR032391|rcsb pdb:3GZ1|rcsb pdb:3GZ2|rcsb pdb:3U0C|rcsb pdb:5WKQ|rcsb pdb:6KEA|refseq:NP_858261.1|refseq:NP_085290.1|refseq:YP_009062485.1|refseq:WP_010921663.1|dip:DIP-45233N"	"go:""GO:0051701""(biological process involved in interaction with host)|go:""GO:0008315""(G2/MI transition of meiotic cell cycle)|go:""GO:0005634""(nucleus)"	-	-	figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2007/09/21	2024/11/06	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	rogid:+VZIF6Bf6eIW6pUUylqTLn/yfW4623	intact-crc:C33CE762A6C60013|rigid:6ksXe3KkoTwXoxUU++/PBiB3/3A	false	myc tag:?-?	green fluorescent protein tag:?-?|sufficient binding region:1-312	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q6XVZ2	uniprotkb:P18206	intact:EBI-7255868|intact:MINT-2842473	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:q6xvz2_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0049""(filter binding)"	Ramarao et al. (2007)	pubmed:17289036|imex:IM-11268|mint:MINT-5219605	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7255876|mint:MINT-4651424|imex:IM-11268-1	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR040658|interpro:IPR015138(Salmonella invasion protein A)|interpro:IPR023225|mint:Q6XVZ2|refseq:WP_005059309.1|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|rcsb pdb:2HSQ|mint:MINT-4651425(identity)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)|mint:MINT-4651426(identity)"	-	comment:mint	-	figure legend:F1C|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/11	2025/02/28	rogid:aC7VgMnktLLeAWbmm0FCl/CuQbQ623	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:46E5B2475EC4B786|rigid:Ox186rtcV4JPmu+ad+AhgFvFrUQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0086""(polyclonal antibody western blot)"
uniprotkb:P08581	uniprotkb:P0DQD2	intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860.3	intact:EBI-1379295|uniprotkb:Q9EXG1|uniprotkb:P25147	psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym)	psi-mi:inlb_lismo(display_long)|uniprotkb:inlB(gene name)|psi-mi:inlB(display_short)|uniprotkb:Invasion protein InlB(gene name synonym)|uniprotkb:lmo0434(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Niemann et al. (2007)	imex:IM-12053|pubmed:17662939	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:169963(lismo)|taxid:169963(""Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1379290|imex:IM-12053-1	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105976.16(gene)|ensembl:ENST00000397752.8(transcript)|go:""GO:0001886""(endothelial cell morphogenesis)|go:""GO:0001889""(liver development)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006909""(phagocytosis)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0031016""(pancreas development)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0061436""(establishment of skin barrier)|go:""GO:0070495""(negative regulation of thrombin-activated receptor signaling pathway)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0098794""(postsynapse)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1901299""(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:""GO:1905098""(negative regulation of guanyl-nucleotide exchange factor activity)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|rcsb pdb:3U6H|rcsb pdb:3U6I|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|rcsb pdb:7V3R|rcsb pdb:7V3S|rcsb pdb:7Y4T|rcsb pdb:7Y4U|rcsb pdb:8AN8|rcsb pdb:8ANS|rcsb pdb:8AU3|rcsb pdb:8AU5|rcsb pdb:8AW1|rcsb pdb:8GVJ|rcsb pdb:8K78|rcsb pdb:8OUU|rcsb pdb:8OUV|rcsb pdb:8OV7|rcsb pdb:8OVZ|rcsb pdb:8OW3|rcsb pdb:8OWG|rcsb pdb:9C1R|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|reactome:R-HSA-9734091|reactome:R-HSA-9825892|refseq:NP_000236.2|refseq:NP_001120972.1|efo:""Orphanet:319298""|efo:""Orphanet:33402""|efo:""Orphanet:47044""|efo:""Orphanet:488265""|efo:""Orphanet:90636""|dip:DIP-6023N|panther:PTHR24416(orthology-group)"	"rcsb pdb:4CIL|rcsb pdb:4AW4|interpro:IPR042229|rcsb pdb:1H6T|rcsb pdb:2UZX|rcsb pdb:2UZY|rcsb pdb:2WQU|rcsb pdb:2WQV|rcsb pdb:2WQW|rcsb pdb:2WQX|rcsb pdb:2Y5P|rcsb pdb:2Y5Q|rcsb pdb:7NMS|rcsb pdb:7PV8|rcsb pdb:7PV9|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0008289""(lipid binding)|go:""GO:0009274""(peptidoglycan-based cell wall)|rcsb pdb:8QP7|panther:PTHR18849(orthology-group)|interpro:IPR050836|rcsb pdb:6DBF|rcsb pdb:6DBG|refseq:NP_463963.1|refseq:WP_010989463.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR013378(Listeria/Bacterioides repeat)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR025875|interpro:IPR025987|interpro:IPR032675|interpro:IPR038200|reactome:R-HSA-8875360|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	figure legend:Figure 1E & 1F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/07/31	2025/03/05	rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606	rogid:HDUmWzNu4ALiX1YiQ3vjqvUDStc169963	intact-crc:805C57F6A5994160|rigid:Jg6X1fXCripGfU+KPiAvqJXmbJI	false	his tag:c-c|necessary binding region:567-741(IPR002909)	sufficient binding region:36-321(IPR001611)|glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08581	uniprotkb:P0DQD2	intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860.3	intact:EBI-1379295|uniprotkb:Q9EXG1|uniprotkb:P25147	psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym)	psi-mi:inlb_lismo(display_long)|uniprotkb:inlB(gene name)|psi-mi:inlB(display_short)|uniprotkb:Invasion protein InlB(gene name synonym)|uniprotkb:lmo0434(locus name)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Niemann et al. (2007)	imex:IM-12053|pubmed:17662939	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:169963(lismo)|taxid:169963(""Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1379437|imex:IM-12053-2	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105976.16(gene)|ensembl:ENST00000397752.8(transcript)|go:""GO:0001886""(endothelial cell morphogenesis)|go:""GO:0001889""(liver development)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006909""(phagocytosis)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0031016""(pancreas development)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0061436""(establishment of skin barrier)|go:""GO:0070495""(negative regulation of thrombin-activated receptor signaling pathway)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0098794""(postsynapse)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1901299""(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:""GO:1905098""(negative regulation of guanyl-nucleotide exchange factor activity)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|rcsb pdb:3U6H|rcsb pdb:3U6I|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|rcsb pdb:7V3R|rcsb pdb:7V3S|rcsb pdb:7Y4T|rcsb pdb:7Y4U|rcsb pdb:8AN8|rcsb pdb:8ANS|rcsb pdb:8AU3|rcsb pdb:8AU5|rcsb pdb:8AW1|rcsb pdb:8GVJ|rcsb pdb:8K78|rcsb pdb:8OUU|rcsb pdb:8OUV|rcsb pdb:8OV7|rcsb pdb:8OVZ|rcsb pdb:8OW3|rcsb pdb:8OWG|rcsb pdb:9C1R|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|reactome:R-HSA-9734091|reactome:R-HSA-9825892|refseq:NP_000236.2|refseq:NP_001120972.1|efo:""Orphanet:319298""|efo:""Orphanet:33402""|efo:""Orphanet:47044""|efo:""Orphanet:488265""|efo:""Orphanet:90636""|dip:DIP-6023N|panther:PTHR24416(orthology-group)"	"rcsb pdb:4CIL|rcsb pdb:4AW4|interpro:IPR042229|rcsb pdb:1H6T|rcsb pdb:2UZX|rcsb pdb:2UZY|rcsb pdb:2WQU|rcsb pdb:2WQV|rcsb pdb:2WQW|rcsb pdb:2WQX|rcsb pdb:2Y5P|rcsb pdb:2Y5Q|rcsb pdb:7NMS|rcsb pdb:7PV8|rcsb pdb:7PV9|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0008289""(lipid binding)|go:""GO:0009274""(peptidoglycan-based cell wall)|rcsb pdb:8QP7|panther:PTHR18849(orthology-group)|interpro:IPR050836|rcsb pdb:6DBF|rcsb pdb:6DBG|refseq:NP_463963.1|refseq:WP_010989463.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR013378(Listeria/Bacterioides repeat)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR025875|interpro:IPR025987|interpro:IPR032675|interpro:IPR038200|reactome:R-HSA-8875360|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	figure legend:Figure 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/07/31	2025/03/05	rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606	rogid:HDUmWzNu4ALiX1YiQ3vjqvUDStc169963	intact-crc:B145136BE1476408|rigid:Jg6X1fXCripGfU+KPiAvqJXmbJI	false	his tag:c-c|necessary binding region:25-928(IPR002909)	sufficient binding region:36-241(IPR001611)|glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P0DQD2	uniprotkb:P08581	intact:EBI-1379295|uniprotkb:Q9EXG1|uniprotkb:P25147	intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860.3	psi-mi:inlb_lismo(display_long)|uniprotkb:inlB(gene name)|psi-mi:inlB(display_short)|uniprotkb:Invasion protein InlB(gene name synonym)|uniprotkb:lmo0434(locus name)	psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Niemann et al. (2007)	imex:IM-12053|pubmed:17662939	"taxid:169963(lismo)|taxid:169963(""Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1379320|wwpdb:2uzx|wwpdb:2uzy|imex:IM-12053-3	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:4CIL|rcsb pdb:4AW4|interpro:IPR042229|rcsb pdb:1H6T|rcsb pdb:2UZX|rcsb pdb:2UZY|rcsb pdb:2WQU|rcsb pdb:2WQV|rcsb pdb:2WQW|rcsb pdb:2WQX|rcsb pdb:2Y5P|rcsb pdb:2Y5Q|rcsb pdb:7NMS|rcsb pdb:7PV8|rcsb pdb:7PV9|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0008289""(lipid binding)|go:""GO:0009274""(peptidoglycan-based cell wall)|rcsb pdb:8QP7|panther:PTHR18849(orthology-group)|interpro:IPR050836|rcsb pdb:6DBF|rcsb pdb:6DBG|refseq:NP_463963.1|refseq:WP_010989463.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR013378(Listeria/Bacterioides repeat)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR025875|interpro:IPR025987|interpro:IPR032675|interpro:IPR038200|reactome:R-HSA-8875360|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)"	"ensembl:ENSG00000105976.16(gene)|ensembl:ENST00000397752.8(transcript)|go:""GO:0001886""(endothelial cell morphogenesis)|go:""GO:0001889""(liver development)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006909""(phagocytosis)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0031016""(pancreas development)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0061436""(establishment of skin barrier)|go:""GO:0070495""(negative regulation of thrombin-activated receptor signaling pathway)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0098794""(postsynapse)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1901299""(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:""GO:1905098""(negative regulation of guanyl-nucleotide exchange factor activity)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|rcsb pdb:3U6H|rcsb pdb:3U6I|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|rcsb pdb:7V3R|rcsb pdb:7V3S|rcsb pdb:7Y4T|rcsb pdb:7Y4U|rcsb pdb:8AN8|rcsb pdb:8ANS|rcsb pdb:8AU3|rcsb pdb:8AU5|rcsb pdb:8AW1|rcsb pdb:8GVJ|rcsb pdb:8K78|rcsb pdb:8OUU|rcsb pdb:8OUV|rcsb pdb:8OV7|rcsb pdb:8OVZ|rcsb pdb:8OW3|rcsb pdb:8OWG|rcsb pdb:9C1R|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|reactome:R-HSA-9734091|reactome:R-HSA-9825892|refseq:NP_000236.2|refseq:NP_001120972.1|efo:""Orphanet:319298""|efo:""Orphanet:33402""|efo:""Orphanet:47044""|efo:""Orphanet:488265""|efo:""Orphanet:90636""|dip:DIP-6023N|panther:PTHR24416(orthology-group)"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	"figure legend:Figure 2 & Supp. Table 1|3d-resolution:""\""2.8A (Deglycosylated), 4.0 (glycosylated)\""""|3d-structure:A contact between the concave face of the InlB LRR region and Met Ig1 forms the primary interface, the secondary, less extensive contact involves the InlB IR region and the Sema domain of Met.|full coverage:Only protein-protein interactions|curation depth:imex curation"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/07/31	2025/03/05	rogid:HDUmWzNu4ALiX1YiQ3vjqvUDStc169963	rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606	intact-crc:6CA0FE65C92ACDEB|rigid:Jg6X1fXCripGfU+KPiAvqJXmbJI	false	sufficient binding region:36-321(IPR001611)|binding-associated region:170-170|binding-associated region:170-170	his tag:c-c|necessary binding region:25-741(IPR002909)|binding-associated region:600-600|binding-associated region:599-599	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08581	uniprotkb:P0DQD2	intact:EBI-1039152|uniprotkb:O60366|uniprotkb:Q12875|uniprotkb:Q9UDX7|uniprotkb:Q9UPL8|uniprotkb:A1L467|uniprotkb:B5A932|uniprotkb:E7EQ94|ensembl:ENSP00000380860.3	intact:EBI-1379295|uniprotkb:Q9EXG1|uniprotkb:P25147	psi-mi:met_human(display_long)|uniprotkb:MET(gene name)|psi-mi:MET(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym)	psi-mi:inlb_lismo(display_long)|uniprotkb:inlB(gene name)|psi-mi:inlB(display_short)|uniprotkb:Invasion protein InlB(gene name synonym)|uniprotkb:lmo0434(locus name)	"psi-mi:""MI:0028""(cosedimentation in solution)"	Niemann et al. (2007)	imex:IM-12053|pubmed:17662939	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:169963(lismo)|taxid:169963(""Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-1379353|imex:IM-12053-4	intact-miscore:0.62	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105976.16(gene)|ensembl:ENST00000397752.8(transcript)|go:""GO:0001886""(endothelial cell morphogenesis)|go:""GO:0001889""(liver development)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006909""(phagocytosis)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0031016""(pancreas development)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0061436""(establishment of skin barrier)|go:""GO:0070495""(negative regulation of thrombin-activated receptor signaling pathway)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0098794""(postsynapse)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1901299""(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:""GO:1905098""(negative regulation of guanyl-nucleotide exchange factor activity)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR031148|interpro:IPR036352|mint:P08581|rcsb pdb:1FYR|rcsb pdb:1R0P|rcsb pdb:1R1W|rcsb pdb:1SHY|rcsb pdb:1SSL|rcsb pdb:2G15|rcsb pdb:2RFN|rcsb pdb:2RFS|rcsb pdb:2UZX|rcsb pdb:2UZY|rcsb pdb:2WD1|rcsb pdb:2WGJ|rcsb pdb:2WKM|rcsb pdb:3A4P|rcsb pdb:3BUX|rcsb pdb:3C1X|rcsb pdb:3CCN|rcsb pdb:3CD8|rcsb pdb:3CE3|rcsb pdb:3CTH|rcsb pdb:3CTJ|rcsb pdb:3DKC|rcsb pdb:3DKF|rcsb pdb:3DKG|rcsb pdb:3EFJ|rcsb pdb:3EFK|rcsb pdb:3F66|rcsb pdb:3F82|rcsb pdb:3I5N|rcsb pdb:3L8V|rcsb pdb:3LQ8|rcsb pdb:3Q6U|rcsb pdb:3Q6W|rcsb pdb:3QTI|rcsb pdb:3R7O|rcsb pdb:3RHK|rcsb pdb:3U6H|rcsb pdb:3U6I|rcsb pdb:3VW8|rcsb pdb:3ZBX|rcsb pdb:3ZC5|rcsb pdb:3ZCL|rcsb pdb:3ZXZ|rcsb pdb:3ZZE|rcsb pdb:4AOI|rcsb pdb:4AP7|rcsb pdb:4DEG|rcsb pdb:4DEH|rcsb pdb:4DEI|rcsb pdb:4EEV|rcsb pdb:4GG5|rcsb pdb:4GG7|rcsb pdb:4IWD|rcsb pdb:4K3J|rcsb pdb:4KNB|rcsb pdb:4MXC|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:4R1V|rcsb pdb:4R1Y|rcsb pdb:4XMO|rcsb pdb:4XYF|rcsb pdb:5DG5|rcsb pdb:5EOB|rcsb pdb:5EYC|rcsb pdb:5EYD|rcsb pdb:5HLW|rcsb pdb:5HNI|rcsb pdb:5HO6|rcsb pdb:5HOA|rcsb pdb:5HOR|rcsb pdb:5HTI|rcsb pdb:5LSP|rcsb pdb:5T3Q|rcsb pdb:5UAB|rcsb pdb:5UAD|rcsb pdb:5YA5|rcsb pdb:6GCU|rcsb pdb:6I04|rcsb pdb:6SD9|rcsb pdb:6SDC|rcsb pdb:6SDD|rcsb pdb:6SDE|rcsb pdb:6UBW|rcsb pdb:6WVZ|rcsb pdb:7B3Q|rcsb pdb:7B3T|rcsb pdb:7B3V|rcsb pdb:7B3W|rcsb pdb:7B3Z|rcsb pdb:7B40|rcsb pdb:7B41|rcsb pdb:7B42|rcsb pdb:7B43|rcsb pdb:7B44|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|rcsb pdb:7V3R|rcsb pdb:7V3S|rcsb pdb:7Y4T|rcsb pdb:7Y4U|rcsb pdb:8AN8|rcsb pdb:8ANS|rcsb pdb:8AU3|rcsb pdb:8AU5|rcsb pdb:8AW1|rcsb pdb:8GVJ|rcsb pdb:8K78|rcsb pdb:8OUU|rcsb pdb:8OUV|rcsb pdb:8OV7|rcsb pdb:8OVZ|rcsb pdb:8OW3|rcsb pdb:8OWG|rcsb pdb:9C1R|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-416550|reactome:R-HSA-5673001|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875360|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|reactome:R-HSA-9022699|reactome:R-HSA-9734091|reactome:R-HSA-9825892|refseq:NP_000236.2|refseq:NP_001120972.1|efo:""Orphanet:319298""|efo:""Orphanet:33402""|efo:""Orphanet:47044""|efo:""Orphanet:488265""|efo:""Orphanet:90636""|dip:DIP-6023N|panther:PTHR24416(orthology-group)"	"rcsb pdb:4CIL|rcsb pdb:4AW4|interpro:IPR042229|rcsb pdb:1H6T|rcsb pdb:2UZX|rcsb pdb:2UZY|rcsb pdb:2WQU|rcsb pdb:2WQV|rcsb pdb:2WQW|rcsb pdb:2WQX|rcsb pdb:2Y5P|rcsb pdb:2Y5Q|rcsb pdb:7NMS|rcsb pdb:7PV8|rcsb pdb:7PV9|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0008289""(lipid binding)|go:""GO:0009274""(peptidoglycan-based cell wall)|rcsb pdb:8QP7|panther:PTHR18849(orthology-group)|interpro:IPR050836|rcsb pdb:6DBF|rcsb pdb:6DBG|refseq:NP_463963.1|refseq:WP_010989463.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR013378(Listeria/Bacterioides repeat)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR025875|interpro:IPR025987|interpro:IPR032675|interpro:IPR038200|reactome:R-HSA-8875360|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like)"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	"figure legend:Figure 6|comment:""\""Equimolar mixtures of InlB321 and Met928 produced a 1:1 complex.\""""|full coverage:Only protein-protein interactions|curation depth:imex curation"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/07/31	2025/03/05	rogid:Xhr+H4h5JjKYOhEqtgK7PNh1brs9606	rogid:HDUmWzNu4ALiX1YiQ3vjqvUDStc169963	intact-crc:B0F826D50716F1E4|rigid:Jg6X1fXCripGfU+KPiAvqJXmbJI	false	his tag:c-c|necessary binding region:25-928	sufficient binding region:36-321(IPR001611)|glutathione s tranferase tag:?-?	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P18010	uniprotkb:P18206	intact:EBI-7640410|intact:MINT-6174234|uniprotkb:Q8VSH8	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:ipaa_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)|uniprotkb:CP0125(locus name)|uniprotkb:70 kDa antigen(gene name synonym)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0114""(x-ray crystallography)"	Nhieu et al. (2007)	pubmed:17932491|imex:IM-14056|mint:MINT-6174226	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7640404|mint:MINT-6174248|imex:IM-14056-3	intact-miscore:0.76	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_085287.1|interpro:IPR015138(Salmonella invasion protein A)|refseq:NP_858258.1|interpro:IPR023225|refseq:YP_009062482.1|refseq:WP_005063225.1|mint:P18010|interpro:IPR040658|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0017166""(vinculin binding)|go:""GO:0030836""(positive regulation of actin filament depolymerization)|rcsb pdb:2GDC|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3RF3|rcsb pdb:5NL1|mint:MINT-6174251(identity)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)|mint:MINT-6174250(identity)"	-	function:Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex ipaA-vinculin induces F-actin depolymerization along with the occasional formation of actin filament bundles|comment:mint	-	comment:The crystal structure was solved to 3.2 A resolution.|figure legend:F1 F2 T1 T2|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/02/04	2025/02/28	rogid:4+8tCJOGJJMiLIFxkqnnF4Jr6w0623	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:1D443CE47009102A|rigid:CnsVdxtkVYkDpUWGQttk1Ddtuok	false	binding-associated region:558-587(MINT-6174272)	binding-associated region:127-258(MINT-6174254)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P18010	uniprotkb:P18206	intact:EBI-7640410|intact:MINT-6174234|uniprotkb:Q8VSH8	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:ipaa_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)|uniprotkb:CP0125(locus name)|uniprotkb:70 kDa antigen(gene name synonym)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0892""(solid phase assay)"	Nhieu et al. (2007)	pubmed:17932491|imex:IM-14056|mint:MINT-6174226	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7640456|mint:MINT-6174283|imex:IM-14056-1	intact-miscore:0.76	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_085287.1|interpro:IPR015138(Salmonella invasion protein A)|refseq:NP_858258.1|interpro:IPR023225|refseq:YP_009062482.1|refseq:WP_005063225.1|mint:P18010|interpro:IPR040658|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0017166""(vinculin binding)|go:""GO:0030836""(positive regulation of actin filament depolymerization)|rcsb pdb:2GDC|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3RF3|rcsb pdb:5NL1|mint:MINT-6174289(identity)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)|mint:MINT-6174285(identity)"	-	function:Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex ipaA-vinculin induces F-actin depolymerization along with the occasional formation of actin filament bundles|comment:mint	-	figure legend:F5|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/02/04	2025/02/28	rogid:4+8tCJOGJJMiLIFxkqnnF4Jr6w0623	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:3A598AE50461C48D|rigid:CnsVdxtkVYkDpUWGQttk1Ddtuok	false	binding-associated region:559-633(MINT-6174290)	binding-associated region:127-258(MINT-6174286)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P18206	uniprotkb:P18010	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	intact:EBI-7640410|intact:MINT-6174234|uniprotkb:Q8VSH8	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	psi-mi:ipaa_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)|uniprotkb:CP0125(locus name)|uniprotkb:70 kDa antigen(gene name synonym)	"psi-mi:""MI:0892""(solid phase assay)"	Nhieu et al. (2007)	pubmed:17932491|imex:IM-14056|mint:MINT-6174226	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7640476|mint:MINT-6174296|imex:IM-14056-2	intact-miscore:0.76	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)|mint:MINT-6174298(identity)"	"refseq:NP_085287.1|interpro:IPR015138(Salmonella invasion protein A)|refseq:NP_858258.1|interpro:IPR023225|refseq:YP_009062482.1|refseq:WP_005063225.1|mint:P18010|interpro:IPR040658|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0017166""(vinculin binding)|go:""GO:0030836""(positive regulation of actin filament depolymerization)|rcsb pdb:2GDC|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3RF3|rcsb pdb:5NL1|mint:MINT-6174302(identity)"	-	-	function:Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex ipaA-vinculin induces F-actin depolymerization along with the occasional formation of actin filament bundles|comment:mint	figure legend:F5|kinetics:kd 3.1 nanomolar|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/02/04	2025/02/28	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	rogid:4+8tCJOGJJMiLIFxkqnnF4Jr6w0623	intact-crc:BBC9EE9430C40EE4|rigid:CnsVdxtkVYkDpUWGQttk1Ddtuok	false	binding-associated region:1-258(MINT-6174299)	binding-associated region:559-633(MINT-6174303)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0H2X3D0	uniprotkb:P05814	intact:EBI-7483161|intact:MINT-5010371	intact:EBI-1642112|uniprotkb:Q4VAZ9|uniprotkb:Q9UCM5|ensembl:ENSP00000341030.3	psi-mi:a0a0h2x3d0_chlta(display_long)|uniprotkb:htrA(gene name)|psi-mi:htrA(display_short)|uniprotkb:CTA_0897(locus name)	psi-mi:casb_human(display_long)|uniprotkb:CSN2(gene name)|psi-mi:CSN2(display_short)|uniprotkb:CASB(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Huston et al. (2007)	pubmed:17604025|imex:IM-10998|mint:MINT-5220085	"taxid:315277(chlta)|taxid:315277(""Chlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7483155|mint:MINT-5010409|imex:IM-10998-1	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_011324883.1|interpro:IPR036034|uniprotkb:Q3KKL6(uniprot-removed-ac)|interpro:IPR041489|mint:A0A0H2X3D0|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0042597""(periplasmic space)|mint:MINT-5010410(identity)"	"refseq:NP_001882.1|refseq:NP_001289699.1|refseq:XP_016863249.1|ensembl:ENSG00000135222.7(gene)|ensembl:ENST00000353151.4(transcript)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007595""(lactation)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR001588(Casein, alpha/beta)|interpro:IPR016345(Casein, beta)|interpro:IPR031305|mint:P05814|reactome:R-HSA-1251985|panther:PTHR11500(orthology-group)|mint:MINT-5010411(identity)"	-	comment:mint	-	figure legend:F1|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/13	2024/11/14	rogid:Q38QHC/WxzJ4MqQ4Y8COu5V4obg315277	rogid:C7aq7sKFs3i5GOrPLzA0ZWDVefk9606	intact-crc:C499EDEFE33BEC70|rigid:hIKlgdndRSGlfkAuCbihCHkDAow	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13688	uniprotkb:Q8GH87	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-7936357|intact:MINT-6798492	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936430|mint:MINT-6798548|imex:IM-9563-10	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798554(identity)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798550(identity)"	-	-	comment:mint	figure legend:f4c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-8(molar)	2008/11/10	2024/11/14	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	intact-crc:74819FFCEBC687C9|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	-	binding-associated region:527-665(MINT-6798551)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8GH87	uniprotkb:P13688	intact:EBI-7936357|intact:MINT-6798492	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	"psi-mi:""MI:0071""(molecular sieving)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936388|mint:MINT-6798525|imex:IM-9563-11	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798527(identity)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798533(identity)"	-	comment:mint	-	figure legend:f4a|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2024/11/14	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	intact-crc:8578ABEDC5AD0D7F|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	binding-associated region:527-665(MINT-6798528)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13688	uniprotkb:Q8GH87	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-7936357|intact:MINT-6798492	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936501|mint:MINT-6798612|imex:IM-9563-7	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798620(identity)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798614(identity)"	-	-	comment:mint	figure legend:f5c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2025/03/26	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	intact-crc:793BC314B333B8A7|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	-	binding-associated region:577-715(MINT-6798617)|mutation decreasing interaction:636-636(MINT-6798615)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13688	uniprotkb:Q8GH87	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-7936357|intact:MINT-6798492	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936521|mint:MINT-6798654|imex:IM-9563-8	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798662(identity)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798656(identity)"	-	-	comment:mint	figure legend:f5c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2025/03/26	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	intact-crc:D155CDB7D23BCD11|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	-	binding-associated region:577-715(MINT-6798657)|mutation disrupting interaction:640-640(MINT-6798659)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13688	uniprotkb:Q8GH87	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-7936357|intact:MINT-6798492	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936481|mint:MINT-6798566|imex:IM-9563-6	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798572(identity)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798568(identity)"	-	-	comment:mint	figure legend:f5c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2025/03/26	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	intact-crc:10AF5EBBC5CD49EB|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	-	binding-associated region:577-715(MINT-6798569)|mutation disrupting interaction:633-633(MINT-6798578)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13688	uniprotkb:Q8GH87	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-7936357|intact:MINT-6798492	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936541|mint:MINT-6798675|imex:IM-9563-9	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798683(identity)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798677(identity)"	-	-	comment:mint	figure legend:f5c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2025/03/26	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	intact-crc:C8203C2D37F9C30B|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	-	binding-associated region:577-715(MINT-6798680)|mutation disrupting interaction:636-636(MINT-6798686)|mutation disrupting interaction:640-640(MINT-6798678)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8GH87	uniprotkb:P13688	intact:EBI-7936357|intact:MINT-6798492	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	"psi-mi:""MI:0028""(cosedimentation in solution)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936456|mint:MINT-6798537|imex:IM-9563-1	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798539(identity)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798543(identity)"	-	comment:mint	-	figure legend:f4b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2024/11/14	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	intact-crc:9D9A1383B6F9E720|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	binding-associated region:527-665(MINT-6798540)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13688	uniprotkb:Q8GH87	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-7936357|intact:MINT-6798492	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	"psi-mi:""MI:0047""(far western blotting)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936576|mint:MINT-6798586|imex:IM-9563-2	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798594(identity)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798588(identity)"	-	-	comment:mint	figure legend:f5c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2024/11/14	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	intact-crc:0FAFA39226562755|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	-	binding-associated region:527-665(MINT-6798591)|mutation disrupting interaction:622-622(MINT-6798589)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13688	uniprotkb:Q8GH87	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-7936357|intact:MINT-6798492	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	"psi-mi:""MI:0047""(far western blotting)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936596|mint:MINT-6798599|imex:IM-9563-3	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798607(identity)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798601(identity)"	-	-	comment:mint	figure legend:f5c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2024/11/14	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	intact-crc:03A64EFB502C5722|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	-	binding-associated region:527-665(MINT-6798602)|mutation decreasing interaction:586-586(MINT-6798604)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8GH87	uniprotkb:P13688	intact:EBI-7936357|intact:MINT-6798492	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936624|mint:MINT-6798690|imex:IM-9563-4	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798692(identity)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798700(identity)"	-	comment:mint	-	figure legend:f5c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2024/11/14	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	intact-crc:1318849DFBF455D6|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	binding-associated region:527-665(MINT-6798695)|mutation disrupting interaction:590-590(MINT-6798697)|mutation disrupting interaction:586-586(MINT-6798693)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P13688	uniprotkb:Q8GH87	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-7936357|intact:MINT-6798492	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	"psi-mi:""MI:0047""(far western blotting)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936658|mint:MINT-6798709|imex:IM-9563-5	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798719(identity)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798711(identity)"	-	-	comment:mint	figure legend:f5c|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2024/11/14	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	intact-crc:ABC8405831242294|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	-	binding-associated region:527-665(MINT-6798714)|mutation disrupting interaction:590-590(MINT-6798712)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P13688	uniprotkb:Q8GH87	intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559.6	intact:EBI-7936357|intact:MINT-6798492	psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 1(gene name synonym)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym)	psi-mi:q8gh87_morca(display_long)|uniprotkb:uspa1(gene name)|psi-mi:uspa1(display_short)	"psi-mi:""MI:0826""(x ray scattering)"	Conners et al. (2008)	pubmed:18497748|imex:IM-9563|mint:MINT-6798483|doi:10.1038/emboj.2008.101	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480(morca)|taxid:480(Moraxella catarrhalis)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7936688|mint:MINT-6798724|imex:IM-9563-13	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|refseq:XP_011525508.1|dip:DIP-42683N|ensembl:ENSG00000079385.23(gene)|ensembl:ENST00000161559.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001568""(blood vessel development)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0015125""(bile acid transmembrane transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019900""(kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030853""(negative regulation of granulocyte differentiation)|go:""GO:0031005""(filamin binding)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032692""(negative regulation of interleukin-1 production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042058""(regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045601""(regulation of endothelial cell differentiation)|go:""GO:0045717""(negative regulation of fatty acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903385""(regulation of homophilic cell adhesion)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000346""(negative regulation of hepatocyte proliferation)|go:""GO:2001214""(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|rcsb pdb:7MU8|rcsb pdb:7RPP|rcsb pdb:8CXJ|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-9854909|panther:PTHR44427(orthology-group)|mint:MINT-6798730(identity)"	"interpro:IPR010494(Protein of unknown function DUF1079)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR005594(YadA-like, C-terminal)|interpro:IPR008378(Ubiquitous surface protein)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|mint:Q8GH87|interpro:IPR045584|mint:MINT-6798726(identity)"	-	-	comment:mint	figure legend:f6|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2024/11/14	rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606	rogid:35+C2Vfu/DI7rdU2sYkxx7soFDg480	intact-crc:EA481A42A54FA257|rigid:+682UJqrlKhUeR74/a6irS6KJ6E	false	-	binding-associated region:527-665(MINT-6798727)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P0A0I7	uniprotkb:P00533	intact:EBI-7213562|uniprotkb:P13131|intact:MINT-4300843	intact:EBI-297353|uniprotkb:Q9BZS2|uniprotkb:Q9GZX1|uniprotkb:Q9H2C9|uniprotkb:Q9H3C9|uniprotkb:Q9UMD7|uniprotkb:Q9UMD8|uniprotkb:Q9UMG5|uniprotkb:O00688|uniprotkb:O00732|uniprotkb:P06268|uniprotkb:Q14225|uniprotkb:Q92795|intact:EBI-28985169|uniprotkb:Q68GS5|ensembl:ENSP00000275493.2	psi-mi:agra_staau(display_long)|uniprotkb:agrA(gene name)|psi-mi:agrA(display_short)|uniprotkb:agr(gene name synonym)	psi-mi:egfr_human(display_long)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:ERBB(gene name synonym)|uniprotkb:HER1(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Gómez et al. (2007)	pubmed:17255933|imex:IM-10950|mint:MINT-5219556	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7213556|mint:MINT-4300861|imex:IM-10950-1	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011006(CheY-like)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR007492(LytTr DNA-binding region)|refseq:WP_000688492.1|mint:P0A0I7|go:""GO:0000156""(phosphorelay response regulator activity)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|rcsb pdb:3BS1|rcsb pdb:4G4K|interpro:IPR046947|mint:MINT-4300863(identity)"	"ensembl:ENSG00000146648.21(gene)|ensembl:ENST00000275493.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001503""(ossification)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001942""(hair follicle development)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007435""(salivary gland morphogenesis)|go:""GO:0007494""(midgut development)|go:""GO:0007611""(learning or memory)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016101""(diterpenoid metabolic process)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0022008""(neurogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0033594""(response to hydroxyisoflavone)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038134""(ERBB2-EGFR signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042311""(vasodilation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042698""(ovulation cycle)|go:""GO:0042743""(hydrogen peroxide metabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0043586""(tongue development)|go:""GO:0045121""(membrane raft)|go:""GO:0045296""(cadherin binding)|go:""GO:0045737""(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048143""(astrocyte activation)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048408""(epidermal growth factor binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048546""(digestive tract morphogenesis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051015""(actin filament binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051205""(protein insertion into membrane)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051968""(positive regulation of synaptic transmission, glutamatergic)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060571""(morphogenesis of an epithelial fold)|go:""GO:0061029""(eyelid development in camera-type eye)|go:""GO:0070141""(response to UV-A)|go:""GO:0070257""(positive regulation of mucus secretion)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070435""(Shc-EGFR complex)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097421""(liver regeneration)|go:""GO:0097489""(multivesicular body, internal vesicle lumen)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900020""(positive regulation of protein kinase C activity)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|go:""GO:1902722""(positive regulation of prolactin secretion)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905208""(negative regulation of cardiocyte differentiation)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|interpro:IPR049328|interpro:IPR050122|mint:P00533|rcsb pdb:1IVO|rcsb pdb:1M14|rcsb pdb:1M17|rcsb pdb:1MOX|rcsb pdb:1NQL|rcsb pdb:1XKK|rcsb pdb:1YY9|rcsb pdb:1Z9I|rcsb pdb:2EB2|rcsb pdb:2EB3|rcsb pdb:2GS2|rcsb pdb:2GS6|rcsb pdb:2GS7|rcsb pdb:2ITN|rcsb pdb:2ITO|rcsb pdb:2ITP|rcsb pdb:2ITQ|rcsb pdb:2ITT|rcsb pdb:2ITU|rcsb pdb:2ITV|rcsb pdb:2ITW|rcsb pdb:2ITX|rcsb pdb:2ITY|rcsb pdb:2ITZ|rcsb pdb:2KS1|rcsb pdb:2J5E|rcsb pdb:2J5F|rcsb pdb:2J6M|rcsb pdb:2JIT|rcsb pdb:2JIU|rcsb pdb:2JIV|rcsb pdb:2M0B|rcsb pdb:2M20|rcsb pdb:2N5S|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:2RGP|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BEL|rcsb pdb:3BUO|rcsb pdb:3C09|rcsb pdb:3G5V|rcsb pdb:3G5Y|rcsb pdb:3GOP|rcsb pdb:3GT8|rcsb pdb:3IKA|rcsb pdb:3LZB|rcsb pdb:3NJP|rcsb pdb:3OB2|rcsb pdb:3OP0|rcsb pdb:3P0Y|rcsb pdb:3PFV|rcsb pdb:3POZ|rcsb pdb:3QWQ|rcsb pdb:3UG1|rcsb pdb:3UG2|rcsb pdb:3VJN|rcsb pdb:3VJO|rcsb pdb:3VRP|rcsb pdb:3VRR|rcsb pdb:3W2O|rcsb pdb:3W2P|rcsb pdb:3W2Q|rcsb pdb:3W2R|rcsb pdb:3W2S|rcsb pdb:3W32|rcsb pdb:3W33|rcsb pdb:4G5J|rcsb pdb:4G5P|rcsb pdb:4HJO|rcsb pdb:4I1Z|rcsb pdb:4I20|rcsb pdb:4I21|rcsb pdb:4I22|rcsb pdb:4I23|rcsb pdb:4I24|rcsb pdb:4JQ7|rcsb pdb:4JQ8|rcsb pdb:4JR3|rcsb pdb:4JRV|rcsb pdb:4KRL|rcsb pdb:4KRM|rcsb pdb:4KRO|rcsb pdb:4KRP|rcsb pdb:4LI5|rcsb pdb:4LL0|rcsb pdb:4LQM|rcsb pdb:4LRM|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4R5S|rcsb pdb:4RIW|rcsb pdb:4RIX|rcsb pdb:4RIY|rcsb pdb:4RJ4|rcsb pdb:4RJ5|rcsb pdb:4RJ6|rcsb pdb:4RJ7|rcsb pdb:4RJ8|rcsb pdb:4TKS|rcsb pdb:4UIP|rcsb pdb:4UV7|rcsb pdb:4WD5|rcsb pdb:4WKQ|rcsb pdb:4WRG|rcsb pdb:4ZAU|rcsb pdb:4ZJV|rcsb pdb:4ZSE|rcsb pdb:5C8K|rcsb pdb:5C8M|rcsb pdb:5C8N|rcsb pdb:5CAL|rcsb pdb:5CAN|rcsb pdb:5CAO|rcsb pdb:5CAP|rcsb pdb:5CAQ|rcsb pdb:5CAS|rcsb pdb:5CAU|rcsb pdb:5CAV|rcsb pdb:5CNN|rcsb pdb:5CNO|rcsb pdb:5CZH|rcsb pdb:5CZI|rcsb pdb:5D41|rcsb pdb:5EDP|rcsb pdb:5EDQ|rcsb pdb:5EDR|rcsb pdb:5EM5|rcsb pdb:5EM6|rcsb pdb:5EM7|rcsb pdb:5EM8|rcsb pdb:5FED|rcsb pdb:5FEE|rcsb pdb:5FEQ|rcsb pdb:5GMP|rcsb pdb:5GNK|rcsb pdb:5GTY|rcsb pdb:5GTZ|rcsb pdb:5HCX|rcsb pdb:5HCY|rcsb pdb:5HCZ|rcsb pdb:5HG5|rcsb pdb:5HG7|rcsb pdb:5HG8|rcsb pdb:5HG9|rcsb pdb:5HIB|rcsb pdb:5HIC|rcsb pdb:5J9Y|rcsb pdb:5J9Z|rcsb pdb:5JEB|rcsb pdb:5LV6|rcsb pdb:5SX4|rcsb pdb:5SX5|rcsb pdb:5U8L|rcsb pdb:5UG8|rcsb pdb:5UG9|rcsb pdb:5UGA|rcsb pdb:5UGB|rcsb pdb:5UGC|rcsb pdb:5UWD|rcsb pdb:5WB7|rcsb pdb:5WB8|rcsb pdb:5X26|rcsb pdb:5X27|rcsb pdb:5X28|rcsb pdb:5X2A|rcsb pdb:5X2C|rcsb pdb:5X2F|rcsb pdb:5X2K|rcsb pdb:5XDK|rcsb pdb:5XDL|rcsb pdb:5XGM|rcsb pdb:5XGN|rcsb pdb:5XWD|rcsb pdb:5Y25|rcsb pdb:5Y9T|rcsb pdb:5YU9|rcsb pdb:5ZTO|rcsb pdb:5ZWJ|rcsb pdb:6ARU|rcsb pdb:6B3S|rcsb pdb:6D8E|rcsb pdb:6DUK|rcsb pdb:6JRJ|rcsb pdb:6JRK|rcsb pdb:6JRX|rcsb pdb:6JWL|rcsb pdb:6JX0|rcsb pdb:6JX4|rcsb pdb:6JXT|rcsb pdb:6JZ0|rcsb pdb:6LUB|rcsb pdb:6LUD|rcsb pdb:6P1D|rcsb pdb:6P1L|rcsb pdb:6P8Q|rcsb pdb:6S89|rcsb pdb:6S8A|rcsb pdb:6S9B|rcsb pdb:6S9C|rcsb pdb:6S9D|rcsb pdb:6TFU|rcsb pdb:6TFV|rcsb pdb:6TFW|rcsb pdb:6TFY|rcsb pdb:6TFZ|rcsb pdb:6TG0|rcsb pdb:6TG1|rcsb pdb:6V5N|rcsb pdb:6V5P|rcsb pdb:6V66|rcsb pdb:6V6K|rcsb pdb:6V6O|rcsb pdb:6VH4|rcsb pdb:6VHN|rcsb pdb:6VHP|rcsb pdb:6WA2|rcsb pdb:6WAK|rcsb pdb:6WXN|rcsb pdb:6XL4|rcsb pdb:6Z4B|rcsb pdb:6Z4D|rcsb pdb:7A2A|rcsb pdb:7A6I|rcsb pdb:7A6J|rcsb pdb:7A6K|rcsb pdb:7AEI|rcsb pdb:7AEM|rcsb pdb:7B85|rcsb pdb:7ER2|rcsb pdb:7JXI|rcsb pdb:7JXK|rcsb pdb:7JXL|rcsb pdb:7JXM|rcsb pdb:7JXP|rcsb pdb:7JXQ|rcsb pdb:7JXW|rcsb pdb:7K1H|rcsb pdb:7K1I|rcsb pdb:7KXZ|rcsb pdb:7KY0|rcsb pdb:7LEN|rcsb pdb:7LFR|rcsb pdb:7LFS|rcsb pdb:7LG8|rcsb pdb:7LGS|rcsb pdb:7LTX|rcsb pdb:7OM4|rcsb pdb:7OXB|rcsb pdb:7SI1|rcsb pdb:7SYD|rcsb pdb:7SYE|rcsb pdb:7SZ0|rcsb pdb:7SZ1|rcsb pdb:8A2B|rcsb pdb:7SZ5|rcsb pdb:7SZ7|rcsb pdb:7T4I|rcsb pdb:7T4J|rcsb pdb:7TVD|rcsb pdb:7U98|rcsb pdb:7U99|rcsb pdb:7U9A|rcsb pdb:7UKV|rcsb pdb:7UKW|rcsb pdb:7VRA|rcsb pdb:7VRE|rcsb pdb:7ZYM|rcsb pdb:7ZYN|rcsb pdb:7ZYP|rcsb pdb:7ZYQ|rcsb pdb:8A27|rcsb pdb:8A2A|rcsb pdb:8A2D|rcsb pdb:8D73|rcsb pdb:8D76|rcsb pdb:8DSW|rcsb pdb:8EME|rcsb pdb:8F1H|rcsb pdb:8F1W|rcsb pdb:8F1X|rcsb pdb:8F1Y|rcsb pdb:8F1Z|rcsb pdb:8FV3|rcsb pdb:8FV4|rcsb pdb:8G63|rcsb pdb:8GB4|rcsb pdb:8GK5|rcsb pdb:8H7X|rcsb pdb:8HGO|rcsb pdb:8HGP|rcsb pdb:8HGS|rcsb pdb:8HV1|rcsb pdb:8HV2|rcsb pdb:8HV3|rcsb pdb:8HV4|rcsb pdb:8HV5|rcsb pdb:8HV6|rcsb pdb:8HV7|rcsb pdb:8HV8|rcsb pdb:8HV9|rcsb pdb:8HVA|rcsb pdb:8HY7|rcsb pdb:8KFQ|rcsb pdb:8PNZ|rcsb pdb:8PO0|rcsb pdb:8PO1|rcsb pdb:8PO2|rcsb pdb:8PO3|rcsb pdb:8PO4|rcsb pdb:8S1M|rcsb pdb:8SC7|rcsb pdb:8TJL|rcsb pdb:8TO3|rcsb pdb:8TO4|rcsb pdb:8UKV|rcsb pdb:8UKW|rcsb pdb:8UKX|rcsb pdb:8WD4|rcsb pdb:9EWT|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-212718|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-445144|reactome:R-HSA-5637810|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8857538|reactome:R-HSA-8863795|reactome:R-HSA-8866910|reactome:R-HSA-9009391|reactome:R-HSA-9013507|reactome:R-HSA-9609690|reactome:R-HSA-9634638|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9820960|refseq:NP_005219.2|refseq:NP_958439.1|refseq:NP_958440.1|refseq:NP_958441.1|dip:DIP-405N|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:294023""|ensembl:ENSP00000275493.2|ensembl:ENST00000342916.7|ensembl:ENSP00000342376.3|ensembl:ENST00000344576.7|ensembl:ENSP00000345973.2|ensembl:ENST00000420316.6|ensembl:ENSP00000413843.2|panther:PTHR24416(orthology-group)|mint:MINT-4300862(identity)"	-	comment:mint|function:Required for high-level post-exponential phase expression of a series of secreted proteins	-	figure legend:F4B|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-1haeo)|taxid:9606(Homo sapiens 1HAEo airway epithelial cell)	-	2007/02/19	2025/03/24	rogid:7J2uM2k5NCstZOLIGG/+W5F/shs1280	rogid:gXB5slVTC+z8DdqqXIzXG7lDwk09606	intact-crc:3E655E6239269AD0|rigid:MXcXkQ+WYzpHUhs31q+FTLl7tug	false	-	mutation disrupting interaction:17-17(MINT-4300927)|mutation decreasing interaction:5-5(MINT-4300930)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P0A0I7	uniprotkb:P00533	intact:EBI-7213562|uniprotkb:P13131|intact:MINT-4300843	intact:EBI-297353|uniprotkb:Q9BZS2|uniprotkb:Q9GZX1|uniprotkb:Q9H2C9|uniprotkb:Q9H3C9|uniprotkb:Q9UMD7|uniprotkb:Q9UMD8|uniprotkb:Q9UMG5|uniprotkb:O00688|uniprotkb:O00732|uniprotkb:P06268|uniprotkb:Q14225|uniprotkb:Q92795|intact:EBI-28985169|uniprotkb:Q68GS5|ensembl:ENSP00000275493.2	psi-mi:agra_staau(display_long)|uniprotkb:agrA(gene name)|psi-mi:agrA(display_short)|uniprotkb:agr(gene name synonym)	psi-mi:egfr_human(display_long)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:ERBB(gene name synonym)|uniprotkb:HER1(gene name synonym)	"psi-mi:""MI:0428""(imaging technique)"	Gómez et al. (2007)	pubmed:17255933|imex:IM-10950|mint:MINT-5219556	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7213963|mint:MINT-4300934|imex:IM-10950-2	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011006(CheY-like)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR007492(LytTr DNA-binding region)|refseq:WP_000688492.1|mint:P0A0I7|go:""GO:0000156""(phosphorelay response regulator activity)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|rcsb pdb:3BS1|rcsb pdb:4G4K|interpro:IPR046947|mint:MINT-4300944(identity)"	"ensembl:ENSG00000146648.21(gene)|ensembl:ENST00000275493.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001503""(ossification)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001942""(hair follicle development)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007435""(salivary gland morphogenesis)|go:""GO:0007494""(midgut development)|go:""GO:0007611""(learning or memory)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016101""(diterpenoid metabolic process)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0022008""(neurogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0033594""(response to hydroxyisoflavone)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038134""(ERBB2-EGFR signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042311""(vasodilation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042698""(ovulation cycle)|go:""GO:0042743""(hydrogen peroxide metabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0043586""(tongue development)|go:""GO:0045121""(membrane raft)|go:""GO:0045296""(cadherin binding)|go:""GO:0045737""(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048143""(astrocyte activation)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048408""(epidermal growth factor binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048546""(digestive tract morphogenesis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051015""(actin filament binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051205""(protein insertion into membrane)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051968""(positive regulation of synaptic transmission, glutamatergic)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060571""(morphogenesis of an epithelial fold)|go:""GO:0061029""(eyelid development in camera-type eye)|go:""GO:0070141""(response to UV-A)|go:""GO:0070257""(positive regulation of mucus secretion)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070435""(Shc-EGFR complex)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097421""(liver regeneration)|go:""GO:0097489""(multivesicular body, internal vesicle lumen)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900020""(positive regulation of protein kinase C activity)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|go:""GO:1902722""(positive regulation of prolactin secretion)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905208""(negative regulation of cardiocyte differentiation)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|interpro:IPR049328|interpro:IPR050122|mint:P00533|rcsb pdb:1IVO|rcsb pdb:1M14|rcsb pdb:1M17|rcsb pdb:1MOX|rcsb pdb:1NQL|rcsb pdb:1XKK|rcsb pdb:1YY9|rcsb pdb:1Z9I|rcsb pdb:2EB2|rcsb pdb:2EB3|rcsb pdb:2GS2|rcsb pdb:2GS6|rcsb pdb:2GS7|rcsb pdb:2ITN|rcsb pdb:2ITO|rcsb pdb:2ITP|rcsb pdb:2ITQ|rcsb pdb:2ITT|rcsb pdb:2ITU|rcsb pdb:2ITV|rcsb pdb:2ITW|rcsb pdb:2ITX|rcsb pdb:2ITY|rcsb pdb:2ITZ|rcsb pdb:2KS1|rcsb pdb:2J5E|rcsb pdb:2J5F|rcsb pdb:2J6M|rcsb pdb:2JIT|rcsb pdb:2JIU|rcsb pdb:2JIV|rcsb pdb:2M0B|rcsb pdb:2M20|rcsb pdb:2N5S|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:2RGP|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BEL|rcsb pdb:3BUO|rcsb pdb:3C09|rcsb pdb:3G5V|rcsb pdb:3G5Y|rcsb pdb:3GOP|rcsb pdb:3GT8|rcsb pdb:3IKA|rcsb pdb:3LZB|rcsb pdb:3NJP|rcsb pdb:3OB2|rcsb pdb:3OP0|rcsb pdb:3P0Y|rcsb pdb:3PFV|rcsb pdb:3POZ|rcsb pdb:3QWQ|rcsb pdb:3UG1|rcsb pdb:3UG2|rcsb pdb:3VJN|rcsb pdb:3VJO|rcsb pdb:3VRP|rcsb pdb:3VRR|rcsb pdb:3W2O|rcsb pdb:3W2P|rcsb pdb:3W2Q|rcsb pdb:3W2R|rcsb pdb:3W2S|rcsb pdb:3W32|rcsb pdb:3W33|rcsb pdb:4G5J|rcsb pdb:4G5P|rcsb pdb:4HJO|rcsb pdb:4I1Z|rcsb pdb:4I20|rcsb pdb:4I21|rcsb pdb:4I22|rcsb pdb:4I23|rcsb pdb:4I24|rcsb pdb:4JQ7|rcsb pdb:4JQ8|rcsb pdb:4JR3|rcsb pdb:4JRV|rcsb pdb:4KRL|rcsb pdb:4KRM|rcsb pdb:4KRO|rcsb pdb:4KRP|rcsb pdb:4LI5|rcsb pdb:4LL0|rcsb pdb:4LQM|rcsb pdb:4LRM|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4R5S|rcsb pdb:4RIW|rcsb pdb:4RIX|rcsb pdb:4RIY|rcsb pdb:4RJ4|rcsb pdb:4RJ5|rcsb pdb:4RJ6|rcsb pdb:4RJ7|rcsb pdb:4RJ8|rcsb pdb:4TKS|rcsb pdb:4UIP|rcsb pdb:4UV7|rcsb pdb:4WD5|rcsb pdb:4WKQ|rcsb pdb:4WRG|rcsb pdb:4ZAU|rcsb pdb:4ZJV|rcsb pdb:4ZSE|rcsb pdb:5C8K|rcsb pdb:5C8M|rcsb pdb:5C8N|rcsb pdb:5CAL|rcsb pdb:5CAN|rcsb pdb:5CAO|rcsb pdb:5CAP|rcsb pdb:5CAQ|rcsb pdb:5CAS|rcsb pdb:5CAU|rcsb pdb:5CAV|rcsb pdb:5CNN|rcsb pdb:5CNO|rcsb pdb:5CZH|rcsb pdb:5CZI|rcsb pdb:5D41|rcsb pdb:5EDP|rcsb pdb:5EDQ|rcsb pdb:5EDR|rcsb pdb:5EM5|rcsb pdb:5EM6|rcsb pdb:5EM7|rcsb pdb:5EM8|rcsb pdb:5FED|rcsb pdb:5FEE|rcsb pdb:5FEQ|rcsb pdb:5GMP|rcsb pdb:5GNK|rcsb pdb:5GTY|rcsb pdb:5GTZ|rcsb pdb:5HCX|rcsb pdb:5HCY|rcsb pdb:5HCZ|rcsb pdb:5HG5|rcsb pdb:5HG7|rcsb pdb:5HG8|rcsb pdb:5HG9|rcsb pdb:5HIB|rcsb pdb:5HIC|rcsb pdb:5J9Y|rcsb pdb:5J9Z|rcsb pdb:5JEB|rcsb pdb:5LV6|rcsb pdb:5SX4|rcsb pdb:5SX5|rcsb pdb:5U8L|rcsb pdb:5UG8|rcsb pdb:5UG9|rcsb pdb:5UGA|rcsb pdb:5UGB|rcsb pdb:5UGC|rcsb pdb:5UWD|rcsb pdb:5WB7|rcsb pdb:5WB8|rcsb pdb:5X26|rcsb pdb:5X27|rcsb pdb:5X28|rcsb pdb:5X2A|rcsb pdb:5X2C|rcsb pdb:5X2F|rcsb pdb:5X2K|rcsb pdb:5XDK|rcsb pdb:5XDL|rcsb pdb:5XGM|rcsb pdb:5XGN|rcsb pdb:5XWD|rcsb pdb:5Y25|rcsb pdb:5Y9T|rcsb pdb:5YU9|rcsb pdb:5ZTO|rcsb pdb:5ZWJ|rcsb pdb:6ARU|rcsb pdb:6B3S|rcsb pdb:6D8E|rcsb pdb:6DUK|rcsb pdb:6JRJ|rcsb pdb:6JRK|rcsb pdb:6JRX|rcsb pdb:6JWL|rcsb pdb:6JX0|rcsb pdb:6JX4|rcsb pdb:6JXT|rcsb pdb:6JZ0|rcsb pdb:6LUB|rcsb pdb:6LUD|rcsb pdb:6P1D|rcsb pdb:6P1L|rcsb pdb:6P8Q|rcsb pdb:6S89|rcsb pdb:6S8A|rcsb pdb:6S9B|rcsb pdb:6S9C|rcsb pdb:6S9D|rcsb pdb:6TFU|rcsb pdb:6TFV|rcsb pdb:6TFW|rcsb pdb:6TFY|rcsb pdb:6TFZ|rcsb pdb:6TG0|rcsb pdb:6TG1|rcsb pdb:6V5N|rcsb pdb:6V5P|rcsb pdb:6V66|rcsb pdb:6V6K|rcsb pdb:6V6O|rcsb pdb:6VH4|rcsb pdb:6VHN|rcsb pdb:6VHP|rcsb pdb:6WA2|rcsb pdb:6WAK|rcsb pdb:6WXN|rcsb pdb:6XL4|rcsb pdb:6Z4B|rcsb pdb:6Z4D|rcsb pdb:7A2A|rcsb pdb:7A6I|rcsb pdb:7A6J|rcsb pdb:7A6K|rcsb pdb:7AEI|rcsb pdb:7AEM|rcsb pdb:7B85|rcsb pdb:7ER2|rcsb pdb:7JXI|rcsb pdb:7JXK|rcsb pdb:7JXL|rcsb pdb:7JXM|rcsb pdb:7JXP|rcsb pdb:7JXQ|rcsb pdb:7JXW|rcsb pdb:7K1H|rcsb pdb:7K1I|rcsb pdb:7KXZ|rcsb pdb:7KY0|rcsb pdb:7LEN|rcsb pdb:7LFR|rcsb pdb:7LFS|rcsb pdb:7LG8|rcsb pdb:7LGS|rcsb pdb:7LTX|rcsb pdb:7OM4|rcsb pdb:7OXB|rcsb pdb:7SI1|rcsb pdb:7SYD|rcsb pdb:7SYE|rcsb pdb:7SZ0|rcsb pdb:7SZ1|rcsb pdb:8A2B|rcsb pdb:7SZ5|rcsb pdb:7SZ7|rcsb pdb:7T4I|rcsb pdb:7T4J|rcsb pdb:7TVD|rcsb pdb:7U98|rcsb pdb:7U99|rcsb pdb:7U9A|rcsb pdb:7UKV|rcsb pdb:7UKW|rcsb pdb:7VRA|rcsb pdb:7VRE|rcsb pdb:7ZYM|rcsb pdb:7ZYN|rcsb pdb:7ZYP|rcsb pdb:7ZYQ|rcsb pdb:8A27|rcsb pdb:8A2A|rcsb pdb:8A2D|rcsb pdb:8D73|rcsb pdb:8D76|rcsb pdb:8DSW|rcsb pdb:8EME|rcsb pdb:8F1H|rcsb pdb:8F1W|rcsb pdb:8F1X|rcsb pdb:8F1Y|rcsb pdb:8F1Z|rcsb pdb:8FV3|rcsb pdb:8FV4|rcsb pdb:8G63|rcsb pdb:8GB4|rcsb pdb:8GK5|rcsb pdb:8H7X|rcsb pdb:8HGO|rcsb pdb:8HGP|rcsb pdb:8HGS|rcsb pdb:8HV1|rcsb pdb:8HV2|rcsb pdb:8HV3|rcsb pdb:8HV4|rcsb pdb:8HV5|rcsb pdb:8HV6|rcsb pdb:8HV7|rcsb pdb:8HV8|rcsb pdb:8HV9|rcsb pdb:8HVA|rcsb pdb:8HY7|rcsb pdb:8KFQ|rcsb pdb:8PNZ|rcsb pdb:8PO0|rcsb pdb:8PO1|rcsb pdb:8PO2|rcsb pdb:8PO3|rcsb pdb:8PO4|rcsb pdb:8S1M|rcsb pdb:8SC7|rcsb pdb:8TJL|rcsb pdb:8TO3|rcsb pdb:8TO4|rcsb pdb:8UKV|rcsb pdb:8UKW|rcsb pdb:8UKX|rcsb pdb:8WD4|rcsb pdb:9EWT|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-212718|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-445144|reactome:R-HSA-5637810|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8857538|reactome:R-HSA-8863795|reactome:R-HSA-8866910|reactome:R-HSA-9009391|reactome:R-HSA-9013507|reactome:R-HSA-9609690|reactome:R-HSA-9634638|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9820960|refseq:NP_005219.2|refseq:NP_958439.1|refseq:NP_958440.1|refseq:NP_958441.1|dip:DIP-405N|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:294023""|ensembl:ENSP00000275493.2|ensembl:ENST00000342916.7|ensembl:ENSP00000342376.3|ensembl:ENST00000344576.7|ensembl:ENSP00000345973.2|ensembl:ENST00000420316.6|ensembl:ENSP00000413843.2|panther:PTHR24416(orthology-group)|mint:MINT-4300935(identity)"	-	comment:mint|function:Required for high-level post-exponential phase expression of a series of secreted proteins	-	figure legend:F4C|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-1haeo)|taxid:9606(Homo sapiens 1HAEo airway epithelial cell)	-	2007/02/19	2025/03/24	rogid:7J2uM2k5NCstZOLIGG/+W5F/shs1280	rogid:gXB5slVTC+z8DdqqXIzXG7lDwk09606	intact-crc:01E42EB5FAE782BF|rigid:MXcXkQ+WYzpHUhs31q+FTLl7tug	false	-	mutation disrupting interaction:17-17(MINT-4300939)	-	-	"psi-mi:""MI:0661""(experimental participant identification)"	"psi-mi:""MI:0661""(experimental participant identification)"
uniprotkb:P63104	uniprotkb:Q933J5	intact:EBI-347088|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6NUR9|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1	intact:EBI-7205718|intact:MINT-4300998	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:q933j5_pseai(display_long)|uniprotkb:exoS(gene name)|psi-mi:exoS(display_short)	"psi-mi:""MI:0114""(x-ray crystallography)"	Ottmann et al. (2007)	pubmed:17235285|imex:IM-11232|mint:MINT-5219528	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:287(pseai)|taxid:287(Pseudomonas aeruginosa)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7205709|mint:MINT-4300987|imex:IM-11232-1	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164924.18(gene)|ensembl:ENST00000353245.7(transcript)|ensembl:ENST00000395951.7(transcript)|ensembl:ENST00000395953.6(transcript)|ensembl:ENST00000395956.7(transcript)|ensembl:ENST00000395957.6(transcript)|ensembl:ENST00000395958.6(transcript)|ensembl:ENST00000419477.6(transcript)|ensembl:ENST00000457309.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001525""(angiogenesis)|go:""GO:0003016""(respiratory system process)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008039""(synaptic target recognition)|go:""GO:0008104""(protein localization)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030324""(lung development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031982""(vesicle)|go:""GO:0035148""(tube formation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0072562""(blood microparticle)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090168""(Golgi reassembly)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63104|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5J31|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|rcsb pdb:7MFD|rcsb pdb:7MFE|rcsb pdb:7MFF|rcsb pdb:7Q16|rcsb pdb:7ZIT|rcsb pdb:8A9G|rcsb pdb:8AH2|rcsb pdb:8QDV|rcsb pdb:8WE2|rcsb pdb:8WF6|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|efo:""Orphanet:178469""|panther:PTHR18860(orthology-group)|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1|ensembl:ENST00000522542.5|ensembl:ENSP00000430072.1|mint:MINT-4300989(identity)"	"refseq:WP_023091063.1|interpro:IPR003540(Binary exotoxin A)|interpro:IPR014773(Yersinia virulence determinant YopE, C-terminal)|interpro:IPR003537(Yersinia virulence determinant YopE)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0016779""(nucleotidyltransferase activity)|interpro:IPR037168|mint:Q933J5|interpro:IPR050999|mint:MINT-4300988(identity)"	-	-	comment:mint	figure legend:F3|figure legend:F4|figure legend:F2|figure legend:F1|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/02/20	2025/03/24	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:iKT+x7tF+bPnEf/RRme4pK4XNjg287	intact-crc:1B02025344FDE7D6|rigid:reehNF7Jy1UwbRAKXCvTMa4cZjE	false	-	binding-associated region:353-453(MINT-4301010)	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06886	uniprotkb:Q8WLQ7	intact:EBI-7247529|intact:MINT-4328940	intact:EBI-7247555|intact:MINT-4328984	psi-mi:tsst_staau(display_long)|uniprotkb:tst(gene name)|psi-mi:tst(display_short)	psi-mi:q8wlq7_human(display_long)|uniprotkb:HLA-DR4(gene name)|psi-mi:HLA-DR4(display_short)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Moza et al. (2007)	pubmed:17268555|imex:IM-11190|mint:MINT-5219593	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7247522|mint:MINT-4328977|imex:IM-11190-1	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)|mint:P06886|go:""GO:0005576""(extracellular region)|go:""GO:0090729""(toxin activity)|rcsb pdb:1AW7|rcsb pdb:1QIL|rcsb pdb:1TS2|rcsb pdb:1TS3|rcsb pdb:1TS4|rcsb pdb:1TS5|rcsb pdb:2IJ0|rcsb pdb:2QIL|rcsb pdb:2TSS|rcsb pdb:3TSS|rcsb pdb:4OHJ|rcsb pdb:4TSS|rcsb pdb:5TSS|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|mint:MINT-4328980(identity)"	"interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|mint:Q8WLQ7|go:""GO:0006955""(immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0042613""(MHC class II protein complex)|interpro:IPR050160|mint:MINT-4328978(identity)"	-	comment:mint|function:Responsible for the symptoms of toxic shock syndrome	"comment:""\""fragmentation type: fragment\""""|comment:mint"	figure legend:F4A|kinetics:kd 1 micromolar|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/02	2024/11/14	rogid:gUTEEBSLOkleiFIZMFrkDj2DSEM1280	rogid:wP8QqVlPatLizathIfoeGDL3KKU9606	intact-crc:5A838C131A266420|rigid:Rro7zrS3yYDSNHY4eR7Mir5ZlNU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01733	uniprotkb:P06886	intact:EBI-6165888|uniprotkb:A0A5A7|uniprotkb:A0A0A6YYD5|ensembl:ENSP00000477916.1|ensembl:ENSP00000487964.1	intact:EBI-7247529|intact:MINT-4328940	psi-mi:tvbl3_human(display_long)|uniprotkb:T-cell receptor beta chain V region YT35(gene name synonym)|uniprotkb:TCRBV12S3(gene name synonym)|uniprotkb:TRBV12-3(gene name)|psi-mi:TRBV12-3(display_short)|uniprotkb:TCRBV8S1(gene name synonym)	psi-mi:tsst_staau(display_long)|uniprotkb:tst(gene name)|psi-mi:tst(display_short)	"psi-mi:""MI:0114""(x-ray crystallography)"	Moza et al. (2007)	pubmed:17268555|imex:IM-11190|mint:MINT-5219593	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7247585|mint:MINT-4328965|imex:IM-11190-2	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000274752.1(gene)|ensembl:ENSG00000282208.1(gene)|ensembl:ENST00000620569.1(transcript)|ensembl:ENST00000633292.1(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0042101""(T cell receptor complex)|go:""GO:0042287""(MHC protein binding)|go:""GO:0042605""(peptide antigen binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050413|mint:P01733|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-389948|panther:PTHR23268(orthology-group)|mint:MINT-4328966(identity)"	"interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)|mint:P06886|go:""GO:0005576""(extracellular region)|go:""GO:0090729""(toxin activity)|rcsb pdb:1AW7|rcsb pdb:1QIL|rcsb pdb:1TS2|rcsb pdb:1TS3|rcsb pdb:1TS4|rcsb pdb:1TS5|rcsb pdb:2IJ0|rcsb pdb:2QIL|rcsb pdb:2TSS|rcsb pdb:3TSS|rcsb pdb:4OHJ|rcsb pdb:4TSS|rcsb pdb:5TSS|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|mint:MINT-4328967(identity)"	-	-	comment:mint|function:Responsible for the symptoms of toxic shock syndrome	figure legend:F2|figure legend:F1|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/02	2024/11/14	rogid:Q1iF+Ih5FyVl9ty4wDJUaAVh/V89606	rogid:gUTEEBSLOkleiFIZMFrkDj2DSEM1280	intact-crc:DE4A71C2C596F750|rigid:van2UUTb3S14BswOsmaHg7XJPcY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q846V4	uniprotkb:P00734	intact:EBI-989571	intact:EBI-297094|ensembl:ENSP00000308541.5|uniprotkb:B2R7F7|uniprotkb:B4E1A7|uniprotkb:Q4QZ40|uniprotkb:Q53H04|uniprotkb:Q53H06|uniprotkb:Q7Z7P3|uniprotkb:Q9UCA1|uniprotkb:Q69EZ7	psi-mi:q846v4_staau(display_long)	psi-mi:thrb_human(display_long)|uniprotkb:F2(gene name)|psi-mi:F2(display_short)|uniprotkb:Coagulation factor II(gene name synonym)	"psi-mi:""MI:0017""(classical fluorescence spectroscopy)"	Panizzi et al. (2006)	imex:IM-14519|pubmed:16230340	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-989914|imex:IM-14519-1	intact-miscore:0.73	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR014874(Staphylcoagulse-N)|interpro:IPR001443(Staphylocoagulase)|rcsb pdb:1NU7|rcsb pdb:1NU9|interpro:IPR043071|interpro:IPR043072	"ensembl:ENSG00000180210.15(gene)|ensembl:ENST00000311907.10(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007596""(blood coagulation)|go:""GO:0008083""(growth factor activity)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010544""(negative regulation of platelet activation)|go:""GO:0030168""(platelet activation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0042730""(fibrinolysis)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048712""(negative regulation of astrocyte differentiation)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051838""(cytolysis by host of symbiont cells)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070493""(thrombin-activated receptor signaling pathway)|go:""GO:0070945""(neutrophil-mediated killing of gram-negative bacterium)|go:""GO:0072562""(blood microparticle)|go:""GO:1900016""(negative regulation of cytokine production involved in inflammatory response)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1900738""(positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:1990806""(ligand-gated ion channel signaling pathway)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000001(Kringle)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003966(Peptidase S1A, prothrombin/thrombin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR018992|interpro:IPR033116|interpro:IPR035972|interpro:IPR037111|interpro:IPR038178|interpro:IPR043504|interpro:IPR051659|mint:P00734|rcsb pdb:1A2C|rcsb pdb:1A3B|rcsb pdb:1A3E|rcsb pdb:1A46|rcsb pdb:1A4W|rcsb pdb:1A5G|rcsb pdb:1A61|rcsb pdb:1ABI|rcsb pdb:1ABJ|rcsb pdb:1AD8|rcsb pdb:1AE8|rcsb pdb:1AFE|rcsb pdb:1AHT|rcsb pdb:1AI8|rcsb pdb:1AIX|rcsb pdb:1AWF|rcsb pdb:1AWH|rcsb pdb:1AY6|rcsb pdb:1B5G|rcsb pdb:1B7X|rcsb pdb:1BA8|rcsb pdb:1BB0|rcsb pdb:1BCU|rcsb pdb:1BHX|rcsb pdb:1BMM|rcsb pdb:1BMN|rcsb pdb:1BTH|rcsb pdb:1C1U|rcsb pdb:1C1V|rcsb pdb:1C1W|rcsb pdb:1C4U|rcsb pdb:1C4V|rcsb pdb:1C4Y|rcsb pdb:1C5L|rcsb pdb:1C5N|rcsb pdb:1C5O|rcsb pdb:1CA8|rcsb pdb:1D3D|rcsb pdb:1D3P|rcsb pdb:1D3Q|rcsb pdb:1D3T|rcsb pdb:1D4P|rcsb pdb:1D6W|rcsb pdb:1D9I|rcsb pdb:1DE7|rcsb pdb:1DIT|rcsb pdb:1DM4|rcsb pdb:1DOJ|rcsb pdb:1DWB|rcsb pdb:1DWC|rcsb pdb:1DWD|rcsb pdb:1DWE|rcsb pdb:1DX5|rcsb pdb:1E0F|rcsb pdb:1EB1|rcsb pdb:1EOJ|rcsb pdb:1EOL|rcsb pdb:1FPC|rcsb pdb:1FPH|rcsb pdb:1G30|rcsb pdb:1G32|rcsb pdb:1G37|rcsb pdb:1GHV|rcsb pdb:1GHW|rcsb pdb:1GHX|rcsb pdb:1GHY|rcsb pdb:1GJ4|rcsb pdb:1GJ5|rcsb pdb:1H8D|rcsb pdb:1H8I|rcsb pdb:1HAG|rcsb pdb:1HAH|rcsb pdb:1HAI|rcsb pdb:1HAO|rcsb pdb:1HAP|rcsb pdb:1HBT|rcsb pdb:1HDT|rcsb pdb:1HGT|rcsb pdb:1HLT|rcsb pdb:1HUT|rcsb pdb:1HXE|rcsb pdb:1HXF|rcsb pdb:1IHS|rcsb pdb:1IHT|rcsb pdb:1JMO|rcsb pdb:1JOU|rcsb pdb:1JWT|rcsb pdb:1K21|rcsb pdb:1K22|rcsb pdb:1KTS|rcsb pdb:1KTT|rcsb pdb:1LHC|rcsb pdb:1LHD|rcsb pdb:1LHE|rcsb pdb:1LHF|rcsb pdb:1LHG|rcsb pdb:1MH0|rcsb pdb:1MU6|rcsb pdb:1MU8|rcsb pdb:1MUE|rcsb pdb:1NM6|rcsb pdb:1NO9|rcsb pdb:1NRN|rcsb pdb:1NRO|rcsb pdb:1NRP|rcsb pdb:1NRQ|rcsb pdb:1NRR|rcsb pdb:1NRS|rcsb pdb:1NT1|rcsb pdb:1NU7|rcsb pdb:1NU9|rcsb pdb:1NY2|rcsb pdb:1NZQ|rcsb pdb:1O0D|rcsb pdb:1O2G|rcsb pdb:1O5G|rcsb pdb:1OOK|rcsb pdb:1OYT|rcsb pdb:1P8V|rcsb pdb:1PPB|rcsb pdb:1QBV|rcsb pdb:1QHR|rcsb pdb:1QJ1|rcsb pdb:1QJ6|rcsb pdb:1QJ7|rcsb pdb:1QUR|rcsb pdb:1RD3|rcsb pdb:1RIW|rcsb pdb:1SB1|rcsb pdb:1SFQ|rcsb pdb:1SG8|rcsb pdb:1SGI|rcsb pdb:1SHH|rcsb pdb:1SL3|rcsb pdb:1SR5|rcsb pdb:1T4U|rcsb pdb:1T4V|rcsb pdb:1TA2|rcsb pdb:1TA6|rcsb pdb:1TB6|rcsb pdb:1TBZ|rcsb pdb:1THP|rcsb pdb:1THR|rcsb pdb:1THS|rcsb pdb:1TMB|rcsb pdb:1TMT|rcsb pdb:1TMU|rcsb pdb:1TOM|rcsb pdb:1TQ0|rcsb pdb:1TQ7|rcsb pdb:1TWX|rcsb pdb:1UMA|rcsb pdb:1UVS|rcsb pdb:1VR1|rcsb pdb:1VZQ|rcsb pdb:1W7G|rcsb pdb:1WAY|rcsb pdb:1WBG|rcsb pdb:1XM1|rcsb pdb:1XMN|rcsb pdb:1YPE|rcsb pdb:1YPG|rcsb pdb:1YPJ|rcsb pdb:1YPK|rcsb pdb:1YPL|rcsb pdb:1YPM|rcsb pdb:1Z71|rcsb pdb:1Z8I|rcsb pdb:1Z8J|rcsb pdb:1ZGI|rcsb pdb:1ZGV|rcsb pdb:1ZRB|rcsb pdb:2A0Q|rcsb pdb:2A2X|rcsb pdb:2A45|rcsb pdb:2AFQ|rcsb pdb:2ANK|rcsb pdb:2ANM|rcsb pdb:2B5T|rcsb pdb:2BDY|rcsb pdb:2BVR|rcsb pdb:2BVS|rcsb pdb:2BVX|rcsb pdb:2BXT|rcsb pdb:2BXU|rcsb pdb:2C8W|rcsb pdb:2C8X|rcsb pdb:2C8Y|rcsb pdb:2C8Z|rcsb pdb:2C90|rcsb pdb:2C93|rcsb pdb:2CF8|rcsb pdb:2CF9|rcsb pdb:2CN0|rcsb pdb:2FEQ|rcsb pdb:2FES|rcsb pdb:2GDE|rcsb pdb:2GP9|rcsb pdb:2H9T|rcsb pdb:2HGT|rcsb pdb:2HNT|rcsb pdb:2HPP|rcsb pdb:2HPQ|rcsb pdb:2HWL|rcsb pdb:2JH0|rcsb pdb:2JH5|rcsb pdb:2JH6|rcsb pdb:2OD3|rcsb pdb:2PGB|rcsb pdb:2PGQ|rcsb pdb:2PKS|rcsb pdb:2PW8|rcsb pdb:2R2M|rcsb pdb:2THF|rcsb pdb:2UUF|rcsb pdb:2UUJ|rcsb pdb:2UUK|rcsb pdb:2V3H|rcsb pdb:2V3O|rcsb pdb:2ZC9|rcsb pdb:2ZDA|rcsb pdb:2ZDV|rcsb pdb:2ZF0|rcsb pdb:2ZFF|rcsb pdb:2ZFP|rcsb pdb:2ZFQ|rcsb pdb:2ZFR|rcsb pdb:2ZG0|rcsb pdb:2ZGB|rcsb pdb:2ZGX|rcsb pdb:2ZHE|rcsb pdb:2ZHF|rcsb pdb:2ZHQ|rcsb pdb:2ZHW|rcsb pdb:2ZI2|rcsb pdb:2ZIQ|rcsb pdb:2ZNK|rcsb pdb:2ZO3|rcsb pdb:3B23|rcsb pdb:3B9F|rcsb pdb:3BEF|rcsb pdb:3BEI|rcsb pdb:3BF6|rcsb pdb:3BIU|rcsb pdb:3BIV|rcsb pdb:3BV9|rcsb pdb:3C1K|rcsb pdb:3C27|rcsb pdb:3D49|rcsb pdb:3DA9|rcsb pdb:3DD2|rcsb pdb:3DHK|rcsb pdb:3DT0|rcsb pdb:3DUX|rcsb pdb:3E6P|rcsb pdb:3EE0|rcsb pdb:3EGK|rcsb pdb:3EQ0|rcsb pdb:3F68|rcsb pdb:3GIC|rcsb pdb:3GIS|rcsb pdb:3HAT|rcsb pdb:3HKJ|rcsb pdb:3HTC|rcsb pdb:3JZ1|rcsb pdb:3JZ2|rcsb pdb:3K65|rcsb pdb:3LDX|rcsb pdb:3LU9|rcsb pdb:3NXP|rcsb pdb:3P17|rcsb pdb:3P6Z|rcsb pdb:3P70|rcsb pdb:3PMH|rcsb pdb:3PO1|rcsb pdb:3QDZ|rcsb pdb:3QGN|rcsb pdb:3QLP|rcsb pdb:3QTO|rcsb pdb:3QTV|rcsb pdb:3QWC|rcsb pdb:3QX5|rcsb pdb:3R3G|rcsb pdb:3RLW|rcsb pdb:3RLY|rcsb pdb:3RM0|rcsb pdb:3RM2|rcsb pdb:3RML|rcsb pdb:3RMM|rcsb pdb:3RMN|rcsb pdb:3RMO|rcsb pdb:3S7H|rcsb pdb:3S7K|rcsb pdb:3SHA|rcsb pdb:3SHC|rcsb pdb:3SI3|rcsb pdb:3SI4|rcsb pdb:3SQE|rcsb pdb:3SQH|rcsb pdb:3SV2|rcsb pdb:3T5F|rcsb pdb:3TU7|rcsb pdb:3U69|rcsb pdb:3U8O|rcsb pdb:3U8R|rcsb pdb:3U8T|rcsb pdb:3U98|rcsb pdb:3U9A|rcsb pdb:3UTU|rcsb pdb:3UWJ|rcsb pdb:3VXE|rcsb pdb:3VXF|rcsb pdb:4AX9|rcsb pdb:4AYV|rcsb pdb:4AYY|rcsb pdb:4AZ2|rcsb pdb:4BAH|rcsb pdb:4BAK|rcsb pdb:4BAM|rcsb pdb:4BAN|rcsb pdb:4BAO|rcsb pdb:4BAQ|rcsb pdb:4BOH|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4DIH|rcsb pdb:4DII|rcsb pdb:4DT7|rcsb pdb:4DY7|rcsb pdb:4E05|rcsb pdb:4E06|rcsb pdb:4E7R|rcsb pdb:4H6S|rcsb pdb:4H6T|rcsb pdb:4HFP|rcsb pdb:4HTC|rcsb pdb:4HZH|rcsb pdb:4I7Y|rcsb pdb:4LOY|rcsb pdb:4LXB|rcsb pdb:4LZ1|rcsb pdb:4LZ4|rcsb pdb:4MLF|rcsb pdb:4NZQ|rcsb pdb:4O03|rcsb pdb:4RKJ|rcsb pdb:4RKO|rcsb pdb:4RN6|rcsb pdb:4THN|rcsb pdb:4UD9|rcsb pdb:4UDW|rcsb pdb:4UE7|rcsb pdb:4UEH|rcsb pdb:4UFD|rcsb pdb:4UFE|rcsb pdb:4UFF|rcsb pdb:4UFG|rcsb pdb:4YES|rcsb pdb:5A2M|rcsb pdb:5AF9|rcsb pdb:5AFY|rcsb pdb:5AFZ|rcsb pdb:5AHG|rcsb pdb:5CMX|rcsb pdb:5DO4|rcsb pdb:5E8E|rcsb pdb:5EDK|rcsb pdb:5EDM|rcsb pdb:5EW1|rcsb pdb:5EW2|rcsb pdb:5GDS|rcsb pdb:5GIM|rcsb pdb:5JDU|rcsb pdb:5JFD|rcsb pdb:5JZY|rcsb pdb:5L6N|rcsb pdb:5MJT|rcsb pdb:5MLS|rcsb pdb:5MM6|rcsb pdb:5NHU|rcsb pdb:5TO3|rcsb pdb:5Z5W|rcsb pdb:5Z5X|rcsb pdb:6BJR|rcsb pdb:6C2W|rcsb pdb:6EO6|rcsb pdb:6EO7|rcsb pdb:6EO8|rcsb pdb:6EO9|rcsb pdb:6V5T|rcsb pdb:7KME|rcsb pdb:7TPP|rcsb pdb:8BWW|rcsb pdb:8KME|rcsb pdb:8UF7|rcsb pdb:9CTH|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-202733|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-416476|reactome:R-HSA-456926|reactome:R-HSA-76009|reactome:R-HSA-9657688|reactome:R-HSA-9672391|reactome:R-HSA-977606|refseq:NP_000497.1|refseq:NP_001298186.1|dip:DIP-6115N|efo:""Orphanet:325""|efo:""Orphanet:329217""|panther:PTHR24254(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:2, 3|comment:Analogues of ProT were competed out by SC.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/15	2024/11/14	rogid:aga3B8obxTGTXoLegjcxl/MIrDY1280	rogid:f6OQ6v3WbFpxr7N6GhfZOHjSsTQ9606	intact-crc:342E9018235582EE|rigid:NM/8xFacvvlontHXf3A0+Un73FI	false	sufficient binding region:1-325|his tag:c-c	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q846V4	uniprotkb:P00734	intact:EBI-989571	intact:EBI-297094|ensembl:ENSP00000308541.5|uniprotkb:B2R7F7|uniprotkb:B4E1A7|uniprotkb:Q4QZ40|uniprotkb:Q53H04|uniprotkb:Q53H06|uniprotkb:Q7Z7P3|uniprotkb:Q9UCA1|uniprotkb:Q69EZ7	psi-mi:q846v4_staau(display_long)	psi-mi:thrb_human(display_long)|uniprotkb:F2(gene name)|psi-mi:F2(display_short)|uniprotkb:Coagulation factor II(gene name synonym)	"psi-mi:""MI:0405""(competition binding)"	Panizzi et al. (2006)	imex:IM-14519|pubmed:16230340	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-990036|imex:IM-14519-2	intact-miscore:0.73	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR014874(Staphylcoagulse-N)|interpro:IPR001443(Staphylocoagulase)|rcsb pdb:1NU7|rcsb pdb:1NU9|interpro:IPR043071|interpro:IPR043072	"ensembl:ENSG00000180210.15(gene)|ensembl:ENST00000311907.10(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007596""(blood coagulation)|go:""GO:0008083""(growth factor activity)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010544""(negative regulation of platelet activation)|go:""GO:0030168""(platelet activation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0042730""(fibrinolysis)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048712""(negative regulation of astrocyte differentiation)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051838""(cytolysis by host of symbiont cells)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070493""(thrombin-activated receptor signaling pathway)|go:""GO:0070945""(neutrophil-mediated killing of gram-negative bacterium)|go:""GO:0072562""(blood microparticle)|go:""GO:1900016""(negative regulation of cytokine production involved in inflammatory response)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1900738""(positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:1990806""(ligand-gated ion channel signaling pathway)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000001(Kringle)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003966(Peptidase S1A, prothrombin/thrombin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR018992|interpro:IPR033116|interpro:IPR035972|interpro:IPR037111|interpro:IPR038178|interpro:IPR043504|interpro:IPR051659|mint:P00734|rcsb pdb:1A2C|rcsb pdb:1A3B|rcsb pdb:1A3E|rcsb pdb:1A46|rcsb pdb:1A4W|rcsb pdb:1A5G|rcsb pdb:1A61|rcsb pdb:1ABI|rcsb pdb:1ABJ|rcsb pdb:1AD8|rcsb pdb:1AE8|rcsb pdb:1AFE|rcsb pdb:1AHT|rcsb pdb:1AI8|rcsb pdb:1AIX|rcsb pdb:1AWF|rcsb pdb:1AWH|rcsb pdb:1AY6|rcsb pdb:1B5G|rcsb pdb:1B7X|rcsb pdb:1BA8|rcsb pdb:1BB0|rcsb pdb:1BCU|rcsb pdb:1BHX|rcsb pdb:1BMM|rcsb pdb:1BMN|rcsb pdb:1BTH|rcsb pdb:1C1U|rcsb pdb:1C1V|rcsb pdb:1C1W|rcsb pdb:1C4U|rcsb pdb:1C4V|rcsb pdb:1C4Y|rcsb pdb:1C5L|rcsb pdb:1C5N|rcsb pdb:1C5O|rcsb pdb:1CA8|rcsb pdb:1D3D|rcsb pdb:1D3P|rcsb pdb:1D3Q|rcsb pdb:1D3T|rcsb pdb:1D4P|rcsb pdb:1D6W|rcsb pdb:1D9I|rcsb pdb:1DE7|rcsb pdb:1DIT|rcsb pdb:1DM4|rcsb pdb:1DOJ|rcsb pdb:1DWB|rcsb pdb:1DWC|rcsb pdb:1DWD|rcsb pdb:1DWE|rcsb pdb:1DX5|rcsb pdb:1E0F|rcsb pdb:1EB1|rcsb pdb:1EOJ|rcsb pdb:1EOL|rcsb pdb:1FPC|rcsb pdb:1FPH|rcsb pdb:1G30|rcsb pdb:1G32|rcsb pdb:1G37|rcsb pdb:1GHV|rcsb pdb:1GHW|rcsb pdb:1GHX|rcsb pdb:1GHY|rcsb pdb:1GJ4|rcsb pdb:1GJ5|rcsb pdb:1H8D|rcsb pdb:1H8I|rcsb pdb:1HAG|rcsb pdb:1HAH|rcsb pdb:1HAI|rcsb pdb:1HAO|rcsb pdb:1HAP|rcsb pdb:1HBT|rcsb pdb:1HDT|rcsb pdb:1HGT|rcsb pdb:1HLT|rcsb pdb:1HUT|rcsb pdb:1HXE|rcsb pdb:1HXF|rcsb pdb:1IHS|rcsb pdb:1IHT|rcsb pdb:1JMO|rcsb pdb:1JOU|rcsb pdb:1JWT|rcsb pdb:1K21|rcsb pdb:1K22|rcsb pdb:1KTS|rcsb pdb:1KTT|rcsb pdb:1LHC|rcsb pdb:1LHD|rcsb pdb:1LHE|rcsb pdb:1LHF|rcsb pdb:1LHG|rcsb pdb:1MH0|rcsb pdb:1MU6|rcsb pdb:1MU8|rcsb pdb:1MUE|rcsb pdb:1NM6|rcsb pdb:1NO9|rcsb pdb:1NRN|rcsb pdb:1NRO|rcsb pdb:1NRP|rcsb pdb:1NRQ|rcsb pdb:1NRR|rcsb pdb:1NRS|rcsb pdb:1NT1|rcsb pdb:1NU7|rcsb pdb:1NU9|rcsb pdb:1NY2|rcsb pdb:1NZQ|rcsb pdb:1O0D|rcsb pdb:1O2G|rcsb pdb:1O5G|rcsb pdb:1OOK|rcsb pdb:1OYT|rcsb pdb:1P8V|rcsb pdb:1PPB|rcsb pdb:1QBV|rcsb pdb:1QHR|rcsb pdb:1QJ1|rcsb pdb:1QJ6|rcsb pdb:1QJ7|rcsb pdb:1QUR|rcsb pdb:1RD3|rcsb pdb:1RIW|rcsb pdb:1SB1|rcsb pdb:1SFQ|rcsb pdb:1SG8|rcsb pdb:1SGI|rcsb pdb:1SHH|rcsb pdb:1SL3|rcsb pdb:1SR5|rcsb pdb:1T4U|rcsb pdb:1T4V|rcsb pdb:1TA2|rcsb pdb:1TA6|rcsb pdb:1TB6|rcsb pdb:1TBZ|rcsb pdb:1THP|rcsb pdb:1THR|rcsb pdb:1THS|rcsb pdb:1TMB|rcsb pdb:1TMT|rcsb pdb:1TMU|rcsb pdb:1TOM|rcsb pdb:1TQ0|rcsb pdb:1TQ7|rcsb pdb:1TWX|rcsb pdb:1UMA|rcsb pdb:1UVS|rcsb pdb:1VR1|rcsb pdb:1VZQ|rcsb pdb:1W7G|rcsb pdb:1WAY|rcsb pdb:1WBG|rcsb pdb:1XM1|rcsb pdb:1XMN|rcsb pdb:1YPE|rcsb pdb:1YPG|rcsb pdb:1YPJ|rcsb pdb:1YPK|rcsb pdb:1YPL|rcsb pdb:1YPM|rcsb pdb:1Z71|rcsb pdb:1Z8I|rcsb pdb:1Z8J|rcsb pdb:1ZGI|rcsb pdb:1ZGV|rcsb pdb:1ZRB|rcsb pdb:2A0Q|rcsb pdb:2A2X|rcsb pdb:2A45|rcsb pdb:2AFQ|rcsb pdb:2ANK|rcsb pdb:2ANM|rcsb pdb:2B5T|rcsb pdb:2BDY|rcsb pdb:2BVR|rcsb pdb:2BVS|rcsb pdb:2BVX|rcsb pdb:2BXT|rcsb pdb:2BXU|rcsb pdb:2C8W|rcsb pdb:2C8X|rcsb pdb:2C8Y|rcsb pdb:2C8Z|rcsb pdb:2C90|rcsb pdb:2C93|rcsb pdb:2CF8|rcsb pdb:2CF9|rcsb pdb:2CN0|rcsb pdb:2FEQ|rcsb pdb:2FES|rcsb pdb:2GDE|rcsb pdb:2GP9|rcsb pdb:2H9T|rcsb pdb:2HGT|rcsb pdb:2HNT|rcsb pdb:2HPP|rcsb pdb:2HPQ|rcsb pdb:2HWL|rcsb pdb:2JH0|rcsb pdb:2JH5|rcsb pdb:2JH6|rcsb pdb:2OD3|rcsb pdb:2PGB|rcsb pdb:2PGQ|rcsb pdb:2PKS|rcsb pdb:2PW8|rcsb pdb:2R2M|rcsb pdb:2THF|rcsb pdb:2UUF|rcsb pdb:2UUJ|rcsb pdb:2UUK|rcsb pdb:2V3H|rcsb pdb:2V3O|rcsb pdb:2ZC9|rcsb pdb:2ZDA|rcsb pdb:2ZDV|rcsb pdb:2ZF0|rcsb pdb:2ZFF|rcsb pdb:2ZFP|rcsb pdb:2ZFQ|rcsb pdb:2ZFR|rcsb pdb:2ZG0|rcsb pdb:2ZGB|rcsb pdb:2ZGX|rcsb pdb:2ZHE|rcsb pdb:2ZHF|rcsb pdb:2ZHQ|rcsb pdb:2ZHW|rcsb pdb:2ZI2|rcsb pdb:2ZIQ|rcsb pdb:2ZNK|rcsb pdb:2ZO3|rcsb pdb:3B23|rcsb pdb:3B9F|rcsb pdb:3BEF|rcsb pdb:3BEI|rcsb pdb:3BF6|rcsb pdb:3BIU|rcsb pdb:3BIV|rcsb pdb:3BV9|rcsb pdb:3C1K|rcsb pdb:3C27|rcsb pdb:3D49|rcsb pdb:3DA9|rcsb pdb:3DD2|rcsb pdb:3DHK|rcsb pdb:3DT0|rcsb pdb:3DUX|rcsb pdb:3E6P|rcsb pdb:3EE0|rcsb pdb:3EGK|rcsb pdb:3EQ0|rcsb pdb:3F68|rcsb pdb:3GIC|rcsb pdb:3GIS|rcsb pdb:3HAT|rcsb pdb:3HKJ|rcsb pdb:3HTC|rcsb pdb:3JZ1|rcsb pdb:3JZ2|rcsb pdb:3K65|rcsb pdb:3LDX|rcsb pdb:3LU9|rcsb pdb:3NXP|rcsb pdb:3P17|rcsb pdb:3P6Z|rcsb pdb:3P70|rcsb pdb:3PMH|rcsb pdb:3PO1|rcsb pdb:3QDZ|rcsb pdb:3QGN|rcsb pdb:3QLP|rcsb pdb:3QTO|rcsb pdb:3QTV|rcsb pdb:3QWC|rcsb pdb:3QX5|rcsb pdb:3R3G|rcsb pdb:3RLW|rcsb pdb:3RLY|rcsb pdb:3RM0|rcsb pdb:3RM2|rcsb pdb:3RML|rcsb pdb:3RMM|rcsb pdb:3RMN|rcsb pdb:3RMO|rcsb pdb:3S7H|rcsb pdb:3S7K|rcsb pdb:3SHA|rcsb pdb:3SHC|rcsb pdb:3SI3|rcsb pdb:3SI4|rcsb pdb:3SQE|rcsb pdb:3SQH|rcsb pdb:3SV2|rcsb pdb:3T5F|rcsb pdb:3TU7|rcsb pdb:3U69|rcsb pdb:3U8O|rcsb pdb:3U8R|rcsb pdb:3U8T|rcsb pdb:3U98|rcsb pdb:3U9A|rcsb pdb:3UTU|rcsb pdb:3UWJ|rcsb pdb:3VXE|rcsb pdb:3VXF|rcsb pdb:4AX9|rcsb pdb:4AYV|rcsb pdb:4AYY|rcsb pdb:4AZ2|rcsb pdb:4BAH|rcsb pdb:4BAK|rcsb pdb:4BAM|rcsb pdb:4BAN|rcsb pdb:4BAO|rcsb pdb:4BAQ|rcsb pdb:4BOH|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4DIH|rcsb pdb:4DII|rcsb pdb:4DT7|rcsb pdb:4DY7|rcsb pdb:4E05|rcsb pdb:4E06|rcsb pdb:4E7R|rcsb pdb:4H6S|rcsb pdb:4H6T|rcsb pdb:4HFP|rcsb pdb:4HTC|rcsb pdb:4HZH|rcsb pdb:4I7Y|rcsb pdb:4LOY|rcsb pdb:4LXB|rcsb pdb:4LZ1|rcsb pdb:4LZ4|rcsb pdb:4MLF|rcsb pdb:4NZQ|rcsb pdb:4O03|rcsb pdb:4RKJ|rcsb pdb:4RKO|rcsb pdb:4RN6|rcsb pdb:4THN|rcsb pdb:4UD9|rcsb pdb:4UDW|rcsb pdb:4UE7|rcsb pdb:4UEH|rcsb pdb:4UFD|rcsb pdb:4UFE|rcsb pdb:4UFF|rcsb pdb:4UFG|rcsb pdb:4YES|rcsb pdb:5A2M|rcsb pdb:5AF9|rcsb pdb:5AFY|rcsb pdb:5AFZ|rcsb pdb:5AHG|rcsb pdb:5CMX|rcsb pdb:5DO4|rcsb pdb:5E8E|rcsb pdb:5EDK|rcsb pdb:5EDM|rcsb pdb:5EW1|rcsb pdb:5EW2|rcsb pdb:5GDS|rcsb pdb:5GIM|rcsb pdb:5JDU|rcsb pdb:5JFD|rcsb pdb:5JZY|rcsb pdb:5L6N|rcsb pdb:5MJT|rcsb pdb:5MLS|rcsb pdb:5MM6|rcsb pdb:5NHU|rcsb pdb:5TO3|rcsb pdb:5Z5W|rcsb pdb:5Z5X|rcsb pdb:6BJR|rcsb pdb:6C2W|rcsb pdb:6EO6|rcsb pdb:6EO7|rcsb pdb:6EO8|rcsb pdb:6EO9|rcsb pdb:6V5T|rcsb pdb:7KME|rcsb pdb:7TPP|rcsb pdb:8BWW|rcsb pdb:8KME|rcsb pdb:8UF7|rcsb pdb:9CTH|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-202733|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-416476|reactome:R-HSA-456926|reactome:R-HSA-76009|reactome:R-HSA-9657688|reactome:R-HSA-9672391|reactome:R-HSA-977606|refseq:NP_000497.1|refseq:NP_001298186.1|dip:DIP-6115N|efo:""Orphanet:325""|efo:""Orphanet:329217""|panther:PTHR24254(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:6|comment:Analogues of ProT were competed out by SC.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/15	2024/11/14	rogid:aga3B8obxTGTXoLegjcxl/MIrDY1280	rogid:f6OQ6v3WbFpxr7N6GhfZOHjSsTQ9606	intact-crc:2D614CE1AA950508|rigid:NM/8xFacvvlontHXf3A0+Un73FI	false	sufficient binding region:1-325	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q846V4	uniprotkb:P00734	intact:EBI-989571	intact:EBI-297094|ensembl:ENSP00000308541.5|uniprotkb:B2R7F7|uniprotkb:B4E1A7|uniprotkb:Q4QZ40|uniprotkb:Q53H04|uniprotkb:Q53H06|uniprotkb:Q7Z7P3|uniprotkb:Q9UCA1|uniprotkb:Q69EZ7	psi-mi:q846v4_staau(display_long)	psi-mi:thrb_human(display_long)|uniprotkb:F2(gene name)|psi-mi:F2(display_short)|uniprotkb:Coagulation factor II(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Panizzi et al. (2006)	imex:IM-14519|pubmed:16230340	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-990051|imex:IM-14519-3	intact-miscore:0.73	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0503""(self)"	"psi-mi:""MI:0684""(ancillary)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR014874(Staphylcoagulse-N)|interpro:IPR001443(Staphylocoagulase)|rcsb pdb:1NU7|rcsb pdb:1NU9|interpro:IPR043071|interpro:IPR043072	"ensembl:ENSG00000180210.15(gene)|ensembl:ENST00000311907.10(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007596""(blood coagulation)|go:""GO:0008083""(growth factor activity)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010544""(negative regulation of platelet activation)|go:""GO:0030168""(platelet activation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0042730""(fibrinolysis)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048712""(negative regulation of astrocyte differentiation)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051838""(cytolysis by host of symbiont cells)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070493""(thrombin-activated receptor signaling pathway)|go:""GO:0070945""(neutrophil-mediated killing of gram-negative bacterium)|go:""GO:0072562""(blood microparticle)|go:""GO:1900016""(negative regulation of cytokine production involved in inflammatory response)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1900738""(positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:1990806""(ligand-gated ion channel signaling pathway)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000001(Kringle)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003966(Peptidase S1A, prothrombin/thrombin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR018992|interpro:IPR033116|interpro:IPR035972|interpro:IPR037111|interpro:IPR038178|interpro:IPR043504|interpro:IPR051659|mint:P00734|rcsb pdb:1A2C|rcsb pdb:1A3B|rcsb pdb:1A3E|rcsb pdb:1A46|rcsb pdb:1A4W|rcsb pdb:1A5G|rcsb pdb:1A61|rcsb pdb:1ABI|rcsb pdb:1ABJ|rcsb pdb:1AD8|rcsb pdb:1AE8|rcsb pdb:1AFE|rcsb pdb:1AHT|rcsb pdb:1AI8|rcsb pdb:1AIX|rcsb pdb:1AWF|rcsb pdb:1AWH|rcsb pdb:1AY6|rcsb pdb:1B5G|rcsb pdb:1B7X|rcsb pdb:1BA8|rcsb pdb:1BB0|rcsb pdb:1BCU|rcsb pdb:1BHX|rcsb pdb:1BMM|rcsb pdb:1BMN|rcsb pdb:1BTH|rcsb pdb:1C1U|rcsb pdb:1C1V|rcsb pdb:1C1W|rcsb pdb:1C4U|rcsb pdb:1C4V|rcsb pdb:1C4Y|rcsb pdb:1C5L|rcsb pdb:1C5N|rcsb pdb:1C5O|rcsb pdb:1CA8|rcsb pdb:1D3D|rcsb pdb:1D3P|rcsb pdb:1D3Q|rcsb pdb:1D3T|rcsb pdb:1D4P|rcsb pdb:1D6W|rcsb pdb:1D9I|rcsb pdb:1DE7|rcsb pdb:1DIT|rcsb pdb:1DM4|rcsb pdb:1DOJ|rcsb pdb:1DWB|rcsb pdb:1DWC|rcsb pdb:1DWD|rcsb pdb:1DWE|rcsb pdb:1DX5|rcsb pdb:1E0F|rcsb pdb:1EB1|rcsb pdb:1EOJ|rcsb pdb:1EOL|rcsb pdb:1FPC|rcsb pdb:1FPH|rcsb pdb:1G30|rcsb pdb:1G32|rcsb pdb:1G37|rcsb pdb:1GHV|rcsb pdb:1GHW|rcsb pdb:1GHX|rcsb pdb:1GHY|rcsb pdb:1GJ4|rcsb pdb:1GJ5|rcsb pdb:1H8D|rcsb pdb:1H8I|rcsb pdb:1HAG|rcsb pdb:1HAH|rcsb pdb:1HAI|rcsb pdb:1HAO|rcsb pdb:1HAP|rcsb pdb:1HBT|rcsb pdb:1HDT|rcsb pdb:1HGT|rcsb pdb:1HLT|rcsb pdb:1HUT|rcsb pdb:1HXE|rcsb pdb:1HXF|rcsb pdb:1IHS|rcsb pdb:1IHT|rcsb pdb:1JMO|rcsb pdb:1JOU|rcsb pdb:1JWT|rcsb pdb:1K21|rcsb pdb:1K22|rcsb pdb:1KTS|rcsb pdb:1KTT|rcsb pdb:1LHC|rcsb pdb:1LHD|rcsb pdb:1LHE|rcsb pdb:1LHF|rcsb pdb:1LHG|rcsb pdb:1MH0|rcsb pdb:1MU6|rcsb pdb:1MU8|rcsb pdb:1MUE|rcsb pdb:1NM6|rcsb pdb:1NO9|rcsb pdb:1NRN|rcsb pdb:1NRO|rcsb pdb:1NRP|rcsb pdb:1NRQ|rcsb pdb:1NRR|rcsb pdb:1NRS|rcsb pdb:1NT1|rcsb pdb:1NU7|rcsb pdb:1NU9|rcsb pdb:1NY2|rcsb pdb:1NZQ|rcsb pdb:1O0D|rcsb pdb:1O2G|rcsb pdb:1O5G|rcsb pdb:1OOK|rcsb pdb:1OYT|rcsb pdb:1P8V|rcsb pdb:1PPB|rcsb pdb:1QBV|rcsb pdb:1QHR|rcsb pdb:1QJ1|rcsb pdb:1QJ6|rcsb pdb:1QJ7|rcsb pdb:1QUR|rcsb pdb:1RD3|rcsb pdb:1RIW|rcsb pdb:1SB1|rcsb pdb:1SFQ|rcsb pdb:1SG8|rcsb pdb:1SGI|rcsb pdb:1SHH|rcsb pdb:1SL3|rcsb pdb:1SR5|rcsb pdb:1T4U|rcsb pdb:1T4V|rcsb pdb:1TA2|rcsb pdb:1TA6|rcsb pdb:1TB6|rcsb pdb:1TBZ|rcsb pdb:1THP|rcsb pdb:1THR|rcsb pdb:1THS|rcsb pdb:1TMB|rcsb pdb:1TMT|rcsb pdb:1TMU|rcsb pdb:1TOM|rcsb pdb:1TQ0|rcsb pdb:1TQ7|rcsb pdb:1TWX|rcsb pdb:1UMA|rcsb pdb:1UVS|rcsb pdb:1VR1|rcsb pdb:1VZQ|rcsb pdb:1W7G|rcsb pdb:1WAY|rcsb pdb:1WBG|rcsb pdb:1XM1|rcsb pdb:1XMN|rcsb pdb:1YPE|rcsb pdb:1YPG|rcsb pdb:1YPJ|rcsb pdb:1YPK|rcsb pdb:1YPL|rcsb pdb:1YPM|rcsb pdb:1Z71|rcsb pdb:1Z8I|rcsb pdb:1Z8J|rcsb pdb:1ZGI|rcsb pdb:1ZGV|rcsb pdb:1ZRB|rcsb pdb:2A0Q|rcsb pdb:2A2X|rcsb pdb:2A45|rcsb pdb:2AFQ|rcsb pdb:2ANK|rcsb pdb:2ANM|rcsb pdb:2B5T|rcsb pdb:2BDY|rcsb pdb:2BVR|rcsb pdb:2BVS|rcsb pdb:2BVX|rcsb pdb:2BXT|rcsb pdb:2BXU|rcsb pdb:2C8W|rcsb pdb:2C8X|rcsb pdb:2C8Y|rcsb pdb:2C8Z|rcsb pdb:2C90|rcsb pdb:2C93|rcsb pdb:2CF8|rcsb pdb:2CF9|rcsb pdb:2CN0|rcsb pdb:2FEQ|rcsb pdb:2FES|rcsb pdb:2GDE|rcsb pdb:2GP9|rcsb pdb:2H9T|rcsb pdb:2HGT|rcsb pdb:2HNT|rcsb pdb:2HPP|rcsb pdb:2HPQ|rcsb pdb:2HWL|rcsb pdb:2JH0|rcsb pdb:2JH5|rcsb pdb:2JH6|rcsb pdb:2OD3|rcsb pdb:2PGB|rcsb pdb:2PGQ|rcsb pdb:2PKS|rcsb pdb:2PW8|rcsb pdb:2R2M|rcsb pdb:2THF|rcsb pdb:2UUF|rcsb pdb:2UUJ|rcsb pdb:2UUK|rcsb pdb:2V3H|rcsb pdb:2V3O|rcsb pdb:2ZC9|rcsb pdb:2ZDA|rcsb pdb:2ZDV|rcsb pdb:2ZF0|rcsb pdb:2ZFF|rcsb pdb:2ZFP|rcsb pdb:2ZFQ|rcsb pdb:2ZFR|rcsb pdb:2ZG0|rcsb pdb:2ZGB|rcsb pdb:2ZGX|rcsb pdb:2ZHE|rcsb pdb:2ZHF|rcsb pdb:2ZHQ|rcsb pdb:2ZHW|rcsb pdb:2ZI2|rcsb pdb:2ZIQ|rcsb pdb:2ZNK|rcsb pdb:2ZO3|rcsb pdb:3B23|rcsb pdb:3B9F|rcsb pdb:3BEF|rcsb pdb:3BEI|rcsb pdb:3BF6|rcsb pdb:3BIU|rcsb pdb:3BIV|rcsb pdb:3BV9|rcsb pdb:3C1K|rcsb pdb:3C27|rcsb pdb:3D49|rcsb pdb:3DA9|rcsb pdb:3DD2|rcsb pdb:3DHK|rcsb pdb:3DT0|rcsb pdb:3DUX|rcsb pdb:3E6P|rcsb pdb:3EE0|rcsb pdb:3EGK|rcsb pdb:3EQ0|rcsb pdb:3F68|rcsb pdb:3GIC|rcsb pdb:3GIS|rcsb pdb:3HAT|rcsb pdb:3HKJ|rcsb pdb:3HTC|rcsb pdb:3JZ1|rcsb pdb:3JZ2|rcsb pdb:3K65|rcsb pdb:3LDX|rcsb pdb:3LU9|rcsb pdb:3NXP|rcsb pdb:3P17|rcsb pdb:3P6Z|rcsb pdb:3P70|rcsb pdb:3PMH|rcsb pdb:3PO1|rcsb pdb:3QDZ|rcsb pdb:3QGN|rcsb pdb:3QLP|rcsb pdb:3QTO|rcsb pdb:3QTV|rcsb pdb:3QWC|rcsb pdb:3QX5|rcsb pdb:3R3G|rcsb pdb:3RLW|rcsb pdb:3RLY|rcsb pdb:3RM0|rcsb pdb:3RM2|rcsb pdb:3RML|rcsb pdb:3RMM|rcsb pdb:3RMN|rcsb pdb:3RMO|rcsb pdb:3S7H|rcsb pdb:3S7K|rcsb pdb:3SHA|rcsb pdb:3SHC|rcsb pdb:3SI3|rcsb pdb:3SI4|rcsb pdb:3SQE|rcsb pdb:3SQH|rcsb pdb:3SV2|rcsb pdb:3T5F|rcsb pdb:3TU7|rcsb pdb:3U69|rcsb pdb:3U8O|rcsb pdb:3U8R|rcsb pdb:3U8T|rcsb pdb:3U98|rcsb pdb:3U9A|rcsb pdb:3UTU|rcsb pdb:3UWJ|rcsb pdb:3VXE|rcsb pdb:3VXF|rcsb pdb:4AX9|rcsb pdb:4AYV|rcsb pdb:4AYY|rcsb pdb:4AZ2|rcsb pdb:4BAH|rcsb pdb:4BAK|rcsb pdb:4BAM|rcsb pdb:4BAN|rcsb pdb:4BAO|rcsb pdb:4BAQ|rcsb pdb:4BOH|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4DIH|rcsb pdb:4DII|rcsb pdb:4DT7|rcsb pdb:4DY7|rcsb pdb:4E05|rcsb pdb:4E06|rcsb pdb:4E7R|rcsb pdb:4H6S|rcsb pdb:4H6T|rcsb pdb:4HFP|rcsb pdb:4HTC|rcsb pdb:4HZH|rcsb pdb:4I7Y|rcsb pdb:4LOY|rcsb pdb:4LXB|rcsb pdb:4LZ1|rcsb pdb:4LZ4|rcsb pdb:4MLF|rcsb pdb:4NZQ|rcsb pdb:4O03|rcsb pdb:4RKJ|rcsb pdb:4RKO|rcsb pdb:4RN6|rcsb pdb:4THN|rcsb pdb:4UD9|rcsb pdb:4UDW|rcsb pdb:4UE7|rcsb pdb:4UEH|rcsb pdb:4UFD|rcsb pdb:4UFE|rcsb pdb:4UFF|rcsb pdb:4UFG|rcsb pdb:4YES|rcsb pdb:5A2M|rcsb pdb:5AF9|rcsb pdb:5AFY|rcsb pdb:5AFZ|rcsb pdb:5AHG|rcsb pdb:5CMX|rcsb pdb:5DO4|rcsb pdb:5E8E|rcsb pdb:5EDK|rcsb pdb:5EDM|rcsb pdb:5EW1|rcsb pdb:5EW2|rcsb pdb:5GDS|rcsb pdb:5GIM|rcsb pdb:5JDU|rcsb pdb:5JFD|rcsb pdb:5JZY|rcsb pdb:5L6N|rcsb pdb:5MJT|rcsb pdb:5MLS|rcsb pdb:5MM6|rcsb pdb:5NHU|rcsb pdb:5TO3|rcsb pdb:5Z5W|rcsb pdb:5Z5X|rcsb pdb:6BJR|rcsb pdb:6C2W|rcsb pdb:6EO6|rcsb pdb:6EO7|rcsb pdb:6EO8|rcsb pdb:6EO9|rcsb pdb:6V5T|rcsb pdb:7KME|rcsb pdb:7TPP|rcsb pdb:8BWW|rcsb pdb:8KME|rcsb pdb:8UF7|rcsb pdb:9CTH|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-202733|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-416476|reactome:R-HSA-456926|reactome:R-HSA-76009|reactome:R-HSA-9657688|reactome:R-HSA-9672391|reactome:R-HSA-977606|refseq:NP_000497.1|refseq:NP_001298186.1|dip:DIP-6115N|efo:""Orphanet:325""|efo:""Orphanet:329217""|panther:PTHR24254(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:4, 5|comment:Increasing concentration of SC resulted in increased self cleavage of ProThrombin.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/15	2024/11/14	rogid:aga3B8obxTGTXoLegjcxl/MIrDY1280	rogid:f6OQ6v3WbFpxr7N6GhfZOHjSsTQ9606	intact-crc:DD08504B8DA78E35|rigid:NM/8xFacvvlontHXf3A0+Un73FI	false	sufficient binding region:1-325	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00734	uniprotkb:Q846V4	intact:EBI-297094|ensembl:ENSP00000308541.5|uniprotkb:B2R7F7|uniprotkb:B4E1A7|uniprotkb:Q4QZ40|uniprotkb:Q53H04|uniprotkb:Q53H06|uniprotkb:Q7Z7P3|uniprotkb:Q9UCA1|uniprotkb:Q69EZ7	intact:EBI-989571	psi-mi:thrb_human(display_long)|uniprotkb:F2(gene name)|psi-mi:F2(display_short)|uniprotkb:Coagulation factor II(gene name synonym)	psi-mi:q846v4_staau(display_long)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Panizzi et al. (2006)	imex:IM-14520|pubmed:16230339	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-989577|imex:IM-14520-1	intact-miscore:0.73	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000180210.15(gene)|ensembl:ENST00000311907.10(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007596""(blood coagulation)|go:""GO:0008083""(growth factor activity)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010544""(negative regulation of platelet activation)|go:""GO:0030168""(platelet activation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0042730""(fibrinolysis)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048712""(negative regulation of astrocyte differentiation)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051838""(cytolysis by host of symbiont cells)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070493""(thrombin-activated receptor signaling pathway)|go:""GO:0070945""(neutrophil-mediated killing of gram-negative bacterium)|go:""GO:0072562""(blood microparticle)|go:""GO:1900016""(negative regulation of cytokine production involved in inflammatory response)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1900738""(positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:1990806""(ligand-gated ion channel signaling pathway)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000001(Kringle)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003966(Peptidase S1A, prothrombin/thrombin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR018992|interpro:IPR033116|interpro:IPR035972|interpro:IPR037111|interpro:IPR038178|interpro:IPR043504|interpro:IPR051659|mint:P00734|rcsb pdb:1A2C|rcsb pdb:1A3B|rcsb pdb:1A3E|rcsb pdb:1A46|rcsb pdb:1A4W|rcsb pdb:1A5G|rcsb pdb:1A61|rcsb pdb:1ABI|rcsb pdb:1ABJ|rcsb pdb:1AD8|rcsb pdb:1AE8|rcsb pdb:1AFE|rcsb pdb:1AHT|rcsb pdb:1AI8|rcsb pdb:1AIX|rcsb pdb:1AWF|rcsb pdb:1AWH|rcsb pdb:1AY6|rcsb pdb:1B5G|rcsb pdb:1B7X|rcsb pdb:1BA8|rcsb pdb:1BB0|rcsb pdb:1BCU|rcsb pdb:1BHX|rcsb pdb:1BMM|rcsb pdb:1BMN|rcsb pdb:1BTH|rcsb pdb:1C1U|rcsb pdb:1C1V|rcsb pdb:1C1W|rcsb pdb:1C4U|rcsb pdb:1C4V|rcsb pdb:1C4Y|rcsb pdb:1C5L|rcsb pdb:1C5N|rcsb pdb:1C5O|rcsb pdb:1CA8|rcsb pdb:1D3D|rcsb pdb:1D3P|rcsb pdb:1D3Q|rcsb pdb:1D3T|rcsb pdb:1D4P|rcsb pdb:1D6W|rcsb pdb:1D9I|rcsb pdb:1DE7|rcsb pdb:1DIT|rcsb pdb:1DM4|rcsb pdb:1DOJ|rcsb pdb:1DWB|rcsb pdb:1DWC|rcsb pdb:1DWD|rcsb pdb:1DWE|rcsb pdb:1DX5|rcsb pdb:1E0F|rcsb pdb:1EB1|rcsb pdb:1EOJ|rcsb pdb:1EOL|rcsb pdb:1FPC|rcsb pdb:1FPH|rcsb pdb:1G30|rcsb pdb:1G32|rcsb pdb:1G37|rcsb pdb:1GHV|rcsb pdb:1GHW|rcsb pdb:1GHX|rcsb pdb:1GHY|rcsb pdb:1GJ4|rcsb pdb:1GJ5|rcsb pdb:1H8D|rcsb pdb:1H8I|rcsb pdb:1HAG|rcsb pdb:1HAH|rcsb pdb:1HAI|rcsb pdb:1HAO|rcsb pdb:1HAP|rcsb pdb:1HBT|rcsb pdb:1HDT|rcsb pdb:1HGT|rcsb pdb:1HLT|rcsb pdb:1HUT|rcsb pdb:1HXE|rcsb pdb:1HXF|rcsb pdb:1IHS|rcsb pdb:1IHT|rcsb pdb:1JMO|rcsb pdb:1JOU|rcsb pdb:1JWT|rcsb pdb:1K21|rcsb pdb:1K22|rcsb pdb:1KTS|rcsb pdb:1KTT|rcsb pdb:1LHC|rcsb pdb:1LHD|rcsb pdb:1LHE|rcsb pdb:1LHF|rcsb pdb:1LHG|rcsb pdb:1MH0|rcsb pdb:1MU6|rcsb pdb:1MU8|rcsb pdb:1MUE|rcsb pdb:1NM6|rcsb pdb:1NO9|rcsb pdb:1NRN|rcsb pdb:1NRO|rcsb pdb:1NRP|rcsb pdb:1NRQ|rcsb pdb:1NRR|rcsb pdb:1NRS|rcsb pdb:1NT1|rcsb pdb:1NU7|rcsb pdb:1NU9|rcsb pdb:1NY2|rcsb pdb:1NZQ|rcsb pdb:1O0D|rcsb pdb:1O2G|rcsb pdb:1O5G|rcsb pdb:1OOK|rcsb pdb:1OYT|rcsb pdb:1P8V|rcsb pdb:1PPB|rcsb pdb:1QBV|rcsb pdb:1QHR|rcsb pdb:1QJ1|rcsb pdb:1QJ6|rcsb pdb:1QJ7|rcsb pdb:1QUR|rcsb pdb:1RD3|rcsb pdb:1RIW|rcsb pdb:1SB1|rcsb pdb:1SFQ|rcsb pdb:1SG8|rcsb pdb:1SGI|rcsb pdb:1SHH|rcsb pdb:1SL3|rcsb pdb:1SR5|rcsb pdb:1T4U|rcsb pdb:1T4V|rcsb pdb:1TA2|rcsb pdb:1TA6|rcsb pdb:1TB6|rcsb pdb:1TBZ|rcsb pdb:1THP|rcsb pdb:1THR|rcsb pdb:1THS|rcsb pdb:1TMB|rcsb pdb:1TMT|rcsb pdb:1TMU|rcsb pdb:1TOM|rcsb pdb:1TQ0|rcsb pdb:1TQ7|rcsb pdb:1TWX|rcsb pdb:1UMA|rcsb pdb:1UVS|rcsb pdb:1VR1|rcsb pdb:1VZQ|rcsb pdb:1W7G|rcsb pdb:1WAY|rcsb pdb:1WBG|rcsb pdb:1XM1|rcsb pdb:1XMN|rcsb pdb:1YPE|rcsb pdb:1YPG|rcsb pdb:1YPJ|rcsb pdb:1YPK|rcsb pdb:1YPL|rcsb pdb:1YPM|rcsb pdb:1Z71|rcsb pdb:1Z8I|rcsb pdb:1Z8J|rcsb pdb:1ZGI|rcsb pdb:1ZGV|rcsb pdb:1ZRB|rcsb pdb:2A0Q|rcsb pdb:2A2X|rcsb pdb:2A45|rcsb pdb:2AFQ|rcsb pdb:2ANK|rcsb pdb:2ANM|rcsb pdb:2B5T|rcsb pdb:2BDY|rcsb pdb:2BVR|rcsb pdb:2BVS|rcsb pdb:2BVX|rcsb pdb:2BXT|rcsb pdb:2BXU|rcsb pdb:2C8W|rcsb pdb:2C8X|rcsb pdb:2C8Y|rcsb pdb:2C8Z|rcsb pdb:2C90|rcsb pdb:2C93|rcsb pdb:2CF8|rcsb pdb:2CF9|rcsb pdb:2CN0|rcsb pdb:2FEQ|rcsb pdb:2FES|rcsb pdb:2GDE|rcsb pdb:2GP9|rcsb pdb:2H9T|rcsb pdb:2HGT|rcsb pdb:2HNT|rcsb pdb:2HPP|rcsb pdb:2HPQ|rcsb pdb:2HWL|rcsb pdb:2JH0|rcsb pdb:2JH5|rcsb pdb:2JH6|rcsb pdb:2OD3|rcsb pdb:2PGB|rcsb pdb:2PGQ|rcsb pdb:2PKS|rcsb pdb:2PW8|rcsb pdb:2R2M|rcsb pdb:2THF|rcsb pdb:2UUF|rcsb pdb:2UUJ|rcsb pdb:2UUK|rcsb pdb:2V3H|rcsb pdb:2V3O|rcsb pdb:2ZC9|rcsb pdb:2ZDA|rcsb pdb:2ZDV|rcsb pdb:2ZF0|rcsb pdb:2ZFF|rcsb pdb:2ZFP|rcsb pdb:2ZFQ|rcsb pdb:2ZFR|rcsb pdb:2ZG0|rcsb pdb:2ZGB|rcsb pdb:2ZGX|rcsb pdb:2ZHE|rcsb pdb:2ZHF|rcsb pdb:2ZHQ|rcsb pdb:2ZHW|rcsb pdb:2ZI2|rcsb pdb:2ZIQ|rcsb pdb:2ZNK|rcsb pdb:2ZO3|rcsb pdb:3B23|rcsb pdb:3B9F|rcsb pdb:3BEF|rcsb pdb:3BEI|rcsb pdb:3BF6|rcsb pdb:3BIU|rcsb pdb:3BIV|rcsb pdb:3BV9|rcsb pdb:3C1K|rcsb pdb:3C27|rcsb pdb:3D49|rcsb pdb:3DA9|rcsb pdb:3DD2|rcsb pdb:3DHK|rcsb pdb:3DT0|rcsb pdb:3DUX|rcsb pdb:3E6P|rcsb pdb:3EE0|rcsb pdb:3EGK|rcsb pdb:3EQ0|rcsb pdb:3F68|rcsb pdb:3GIC|rcsb pdb:3GIS|rcsb pdb:3HAT|rcsb pdb:3HKJ|rcsb pdb:3HTC|rcsb pdb:3JZ1|rcsb pdb:3JZ2|rcsb pdb:3K65|rcsb pdb:3LDX|rcsb pdb:3LU9|rcsb pdb:3NXP|rcsb pdb:3P17|rcsb pdb:3P6Z|rcsb pdb:3P70|rcsb pdb:3PMH|rcsb pdb:3PO1|rcsb pdb:3QDZ|rcsb pdb:3QGN|rcsb pdb:3QLP|rcsb pdb:3QTO|rcsb pdb:3QTV|rcsb pdb:3QWC|rcsb pdb:3QX5|rcsb pdb:3R3G|rcsb pdb:3RLW|rcsb pdb:3RLY|rcsb pdb:3RM0|rcsb pdb:3RM2|rcsb pdb:3RML|rcsb pdb:3RMM|rcsb pdb:3RMN|rcsb pdb:3RMO|rcsb pdb:3S7H|rcsb pdb:3S7K|rcsb pdb:3SHA|rcsb pdb:3SHC|rcsb pdb:3SI3|rcsb pdb:3SI4|rcsb pdb:3SQE|rcsb pdb:3SQH|rcsb pdb:3SV2|rcsb pdb:3T5F|rcsb pdb:3TU7|rcsb pdb:3U69|rcsb pdb:3U8O|rcsb pdb:3U8R|rcsb pdb:3U8T|rcsb pdb:3U98|rcsb pdb:3U9A|rcsb pdb:3UTU|rcsb pdb:3UWJ|rcsb pdb:3VXE|rcsb pdb:3VXF|rcsb pdb:4AX9|rcsb pdb:4AYV|rcsb pdb:4AYY|rcsb pdb:4AZ2|rcsb pdb:4BAH|rcsb pdb:4BAK|rcsb pdb:4BAM|rcsb pdb:4BAN|rcsb pdb:4BAO|rcsb pdb:4BAQ|rcsb pdb:4BOH|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4DIH|rcsb pdb:4DII|rcsb pdb:4DT7|rcsb pdb:4DY7|rcsb pdb:4E05|rcsb pdb:4E06|rcsb pdb:4E7R|rcsb pdb:4H6S|rcsb pdb:4H6T|rcsb pdb:4HFP|rcsb pdb:4HTC|rcsb pdb:4HZH|rcsb pdb:4I7Y|rcsb pdb:4LOY|rcsb pdb:4LXB|rcsb pdb:4LZ1|rcsb pdb:4LZ4|rcsb pdb:4MLF|rcsb pdb:4NZQ|rcsb pdb:4O03|rcsb pdb:4RKJ|rcsb pdb:4RKO|rcsb pdb:4RN6|rcsb pdb:4THN|rcsb pdb:4UD9|rcsb pdb:4UDW|rcsb pdb:4UE7|rcsb pdb:4UEH|rcsb pdb:4UFD|rcsb pdb:4UFE|rcsb pdb:4UFF|rcsb pdb:4UFG|rcsb pdb:4YES|rcsb pdb:5A2M|rcsb pdb:5AF9|rcsb pdb:5AFY|rcsb pdb:5AFZ|rcsb pdb:5AHG|rcsb pdb:5CMX|rcsb pdb:5DO4|rcsb pdb:5E8E|rcsb pdb:5EDK|rcsb pdb:5EDM|rcsb pdb:5EW1|rcsb pdb:5EW2|rcsb pdb:5GDS|rcsb pdb:5GIM|rcsb pdb:5JDU|rcsb pdb:5JFD|rcsb pdb:5JZY|rcsb pdb:5L6N|rcsb pdb:5MJT|rcsb pdb:5MLS|rcsb pdb:5MM6|rcsb pdb:5NHU|rcsb pdb:5TO3|rcsb pdb:5Z5W|rcsb pdb:5Z5X|rcsb pdb:6BJR|rcsb pdb:6C2W|rcsb pdb:6EO6|rcsb pdb:6EO7|rcsb pdb:6EO8|rcsb pdb:6EO9|rcsb pdb:6V5T|rcsb pdb:7KME|rcsb pdb:7TPP|rcsb pdb:8BWW|rcsb pdb:8KME|rcsb pdb:8UF7|rcsb pdb:9CTH|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-202733|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-416476|reactome:R-HSA-456926|reactome:R-HSA-76009|reactome:R-HSA-9657688|reactome:R-HSA-9672391|reactome:R-HSA-977606|refseq:NP_000497.1|refseq:NP_001298186.1|dip:DIP-6115N|efo:""Orphanet:325""|efo:""Orphanet:329217""|panther:PTHR24254(orthology-group)"	interpro:IPR014874(Staphylcoagulse-N)|interpro:IPR001443(Staphylocoagulase)|rcsb pdb:1NU7|rcsb pdb:1NU9|interpro:IPR043071|interpro:IPR043072	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:4A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/15	2024/11/14	rogid:f6OQ6v3WbFpxr7N6GhfZOHjSsTQ9606	rogid:aga3B8obxTGTXoLegjcxl/MIrDY1280	intact-crc:F50F84F44B741CC8|rigid:NM/8xFacvvlontHXf3A0+Un73FI	false	-	sufficient binding region:1-325	1	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00734	uniprotkb:Q846V4	intact:EBI-297094|ensembl:ENSP00000308541.5|uniprotkb:B2R7F7|uniprotkb:B4E1A7|uniprotkb:Q4QZ40|uniprotkb:Q53H04|uniprotkb:Q53H06|uniprotkb:Q7Z7P3|uniprotkb:Q9UCA1|uniprotkb:Q69EZ7	intact:EBI-989571	psi-mi:thrb_human(display_long)|uniprotkb:F2(gene name)|psi-mi:F2(display_short)|uniprotkb:Coagulation factor II(gene name synonym)	psi-mi:q846v4_staau(display_long)	"psi-mi:""MI:0404""(comigration in non denaturing gel electrophoresis)"	Panizzi et al. (2006)	imex:IM-14520|pubmed:16230339	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-989711|imex:IM-14520-2	intact-miscore:0.73	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000180210.15(gene)|ensembl:ENST00000311907.10(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006953""(acute-phase response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007596""(blood coagulation)|go:""GO:0008083""(growth factor activity)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010544""(negative regulation of platelet activation)|go:""GO:0030168""(platelet activation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0042730""(fibrinolysis)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048712""(negative regulation of astrocyte differentiation)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051838""(cytolysis by host of symbiont cells)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070493""(thrombin-activated receptor signaling pathway)|go:""GO:0070945""(neutrophil-mediated killing of gram-negative bacterium)|go:""GO:0072562""(blood microparticle)|go:""GO:1900016""(negative regulation of cytokine production involved in inflammatory response)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1900738""(positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:1990806""(ligand-gated ion channel signaling pathway)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000001(Kringle)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003966(Peptidase S1A, prothrombin/thrombin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR018992|interpro:IPR033116|interpro:IPR035972|interpro:IPR037111|interpro:IPR038178|interpro:IPR043504|interpro:IPR051659|mint:P00734|rcsb pdb:1A2C|rcsb pdb:1A3B|rcsb pdb:1A3E|rcsb pdb:1A46|rcsb pdb:1A4W|rcsb pdb:1A5G|rcsb pdb:1A61|rcsb pdb:1ABI|rcsb pdb:1ABJ|rcsb pdb:1AD8|rcsb pdb:1AE8|rcsb pdb:1AFE|rcsb pdb:1AHT|rcsb pdb:1AI8|rcsb pdb:1AIX|rcsb pdb:1AWF|rcsb pdb:1AWH|rcsb pdb:1AY6|rcsb pdb:1B5G|rcsb pdb:1B7X|rcsb pdb:1BA8|rcsb pdb:1BB0|rcsb pdb:1BCU|rcsb pdb:1BHX|rcsb pdb:1BMM|rcsb pdb:1BMN|rcsb pdb:1BTH|rcsb pdb:1C1U|rcsb pdb:1C1V|rcsb pdb:1C1W|rcsb pdb:1C4U|rcsb pdb:1C4V|rcsb pdb:1C4Y|rcsb pdb:1C5L|rcsb pdb:1C5N|rcsb pdb:1C5O|rcsb pdb:1CA8|rcsb pdb:1D3D|rcsb pdb:1D3P|rcsb pdb:1D3Q|rcsb pdb:1D3T|rcsb pdb:1D4P|rcsb pdb:1D6W|rcsb pdb:1D9I|rcsb pdb:1DE7|rcsb pdb:1DIT|rcsb pdb:1DM4|rcsb pdb:1DOJ|rcsb pdb:1DWB|rcsb pdb:1DWC|rcsb pdb:1DWD|rcsb pdb:1DWE|rcsb pdb:1DX5|rcsb pdb:1E0F|rcsb pdb:1EB1|rcsb pdb:1EOJ|rcsb pdb:1EOL|rcsb pdb:1FPC|rcsb pdb:1FPH|rcsb pdb:1G30|rcsb pdb:1G32|rcsb pdb:1G37|rcsb pdb:1GHV|rcsb pdb:1GHW|rcsb pdb:1GHX|rcsb pdb:1GHY|rcsb pdb:1GJ4|rcsb pdb:1GJ5|rcsb pdb:1H8D|rcsb pdb:1H8I|rcsb pdb:1HAG|rcsb pdb:1HAH|rcsb pdb:1HAI|rcsb pdb:1HAO|rcsb pdb:1HAP|rcsb pdb:1HBT|rcsb pdb:1HDT|rcsb pdb:1HGT|rcsb pdb:1HLT|rcsb pdb:1HUT|rcsb pdb:1HXE|rcsb pdb:1HXF|rcsb pdb:1IHS|rcsb pdb:1IHT|rcsb pdb:1JMO|rcsb pdb:1JOU|rcsb pdb:1JWT|rcsb pdb:1K21|rcsb pdb:1K22|rcsb pdb:1KTS|rcsb pdb:1KTT|rcsb pdb:1LHC|rcsb pdb:1LHD|rcsb pdb:1LHE|rcsb pdb:1LHF|rcsb pdb:1LHG|rcsb pdb:1MH0|rcsb pdb:1MU6|rcsb pdb:1MU8|rcsb pdb:1MUE|rcsb pdb:1NM6|rcsb pdb:1NO9|rcsb pdb:1NRN|rcsb pdb:1NRO|rcsb pdb:1NRP|rcsb pdb:1NRQ|rcsb pdb:1NRR|rcsb pdb:1NRS|rcsb pdb:1NT1|rcsb pdb:1NU7|rcsb pdb:1NU9|rcsb pdb:1NY2|rcsb pdb:1NZQ|rcsb pdb:1O0D|rcsb pdb:1O2G|rcsb pdb:1O5G|rcsb pdb:1OOK|rcsb pdb:1OYT|rcsb pdb:1P8V|rcsb pdb:1PPB|rcsb pdb:1QBV|rcsb pdb:1QHR|rcsb pdb:1QJ1|rcsb pdb:1QJ6|rcsb pdb:1QJ7|rcsb pdb:1QUR|rcsb pdb:1RD3|rcsb pdb:1RIW|rcsb pdb:1SB1|rcsb pdb:1SFQ|rcsb pdb:1SG8|rcsb pdb:1SGI|rcsb pdb:1SHH|rcsb pdb:1SL3|rcsb pdb:1SR5|rcsb pdb:1T4U|rcsb pdb:1T4V|rcsb pdb:1TA2|rcsb pdb:1TA6|rcsb pdb:1TB6|rcsb pdb:1TBZ|rcsb pdb:1THP|rcsb pdb:1THR|rcsb pdb:1THS|rcsb pdb:1TMB|rcsb pdb:1TMT|rcsb pdb:1TMU|rcsb pdb:1TOM|rcsb pdb:1TQ0|rcsb pdb:1TQ7|rcsb pdb:1TWX|rcsb pdb:1UMA|rcsb pdb:1UVS|rcsb pdb:1VR1|rcsb pdb:1VZQ|rcsb pdb:1W7G|rcsb pdb:1WAY|rcsb pdb:1WBG|rcsb pdb:1XM1|rcsb pdb:1XMN|rcsb pdb:1YPE|rcsb pdb:1YPG|rcsb pdb:1YPJ|rcsb pdb:1YPK|rcsb pdb:1YPL|rcsb pdb:1YPM|rcsb pdb:1Z71|rcsb pdb:1Z8I|rcsb pdb:1Z8J|rcsb pdb:1ZGI|rcsb pdb:1ZGV|rcsb pdb:1ZRB|rcsb pdb:2A0Q|rcsb pdb:2A2X|rcsb pdb:2A45|rcsb pdb:2AFQ|rcsb pdb:2ANK|rcsb pdb:2ANM|rcsb pdb:2B5T|rcsb pdb:2BDY|rcsb pdb:2BVR|rcsb pdb:2BVS|rcsb pdb:2BVX|rcsb pdb:2BXT|rcsb pdb:2BXU|rcsb pdb:2C8W|rcsb pdb:2C8X|rcsb pdb:2C8Y|rcsb pdb:2C8Z|rcsb pdb:2C90|rcsb pdb:2C93|rcsb pdb:2CF8|rcsb pdb:2CF9|rcsb pdb:2CN0|rcsb pdb:2FEQ|rcsb pdb:2FES|rcsb pdb:2GDE|rcsb pdb:2GP9|rcsb pdb:2H9T|rcsb pdb:2HGT|rcsb pdb:2HNT|rcsb pdb:2HPP|rcsb pdb:2HPQ|rcsb pdb:2HWL|rcsb pdb:2JH0|rcsb pdb:2JH5|rcsb pdb:2JH6|rcsb pdb:2OD3|rcsb pdb:2PGB|rcsb pdb:2PGQ|rcsb pdb:2PKS|rcsb pdb:2PW8|rcsb pdb:2R2M|rcsb pdb:2THF|rcsb pdb:2UUF|rcsb pdb:2UUJ|rcsb pdb:2UUK|rcsb pdb:2V3H|rcsb pdb:2V3O|rcsb pdb:2ZC9|rcsb pdb:2ZDA|rcsb pdb:2ZDV|rcsb pdb:2ZF0|rcsb pdb:2ZFF|rcsb pdb:2ZFP|rcsb pdb:2ZFQ|rcsb pdb:2ZFR|rcsb pdb:2ZG0|rcsb pdb:2ZGB|rcsb pdb:2ZGX|rcsb pdb:2ZHE|rcsb pdb:2ZHF|rcsb pdb:2ZHQ|rcsb pdb:2ZHW|rcsb pdb:2ZI2|rcsb pdb:2ZIQ|rcsb pdb:2ZNK|rcsb pdb:2ZO3|rcsb pdb:3B23|rcsb pdb:3B9F|rcsb pdb:3BEF|rcsb pdb:3BEI|rcsb pdb:3BF6|rcsb pdb:3BIU|rcsb pdb:3BIV|rcsb pdb:3BV9|rcsb pdb:3C1K|rcsb pdb:3C27|rcsb pdb:3D49|rcsb pdb:3DA9|rcsb pdb:3DD2|rcsb pdb:3DHK|rcsb pdb:3DT0|rcsb pdb:3DUX|rcsb pdb:3E6P|rcsb pdb:3EE0|rcsb pdb:3EGK|rcsb pdb:3EQ0|rcsb pdb:3F68|rcsb pdb:3GIC|rcsb pdb:3GIS|rcsb pdb:3HAT|rcsb pdb:3HKJ|rcsb pdb:3HTC|rcsb pdb:3JZ1|rcsb pdb:3JZ2|rcsb pdb:3K65|rcsb pdb:3LDX|rcsb pdb:3LU9|rcsb pdb:3NXP|rcsb pdb:3P17|rcsb pdb:3P6Z|rcsb pdb:3P70|rcsb pdb:3PMH|rcsb pdb:3PO1|rcsb pdb:3QDZ|rcsb pdb:3QGN|rcsb pdb:3QLP|rcsb pdb:3QTO|rcsb pdb:3QTV|rcsb pdb:3QWC|rcsb pdb:3QX5|rcsb pdb:3R3G|rcsb pdb:3RLW|rcsb pdb:3RLY|rcsb pdb:3RM0|rcsb pdb:3RM2|rcsb pdb:3RML|rcsb pdb:3RMM|rcsb pdb:3RMN|rcsb pdb:3RMO|rcsb pdb:3S7H|rcsb pdb:3S7K|rcsb pdb:3SHA|rcsb pdb:3SHC|rcsb pdb:3SI3|rcsb pdb:3SI4|rcsb pdb:3SQE|rcsb pdb:3SQH|rcsb pdb:3SV2|rcsb pdb:3T5F|rcsb pdb:3TU7|rcsb pdb:3U69|rcsb pdb:3U8O|rcsb pdb:3U8R|rcsb pdb:3U8T|rcsb pdb:3U98|rcsb pdb:3U9A|rcsb pdb:3UTU|rcsb pdb:3UWJ|rcsb pdb:3VXE|rcsb pdb:3VXF|rcsb pdb:4AX9|rcsb pdb:4AYV|rcsb pdb:4AYY|rcsb pdb:4AZ2|rcsb pdb:4BAH|rcsb pdb:4BAK|rcsb pdb:4BAM|rcsb pdb:4BAN|rcsb pdb:4BAO|rcsb pdb:4BAQ|rcsb pdb:4BOH|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4DIH|rcsb pdb:4DII|rcsb pdb:4DT7|rcsb pdb:4DY7|rcsb pdb:4E05|rcsb pdb:4E06|rcsb pdb:4E7R|rcsb pdb:4H6S|rcsb pdb:4H6T|rcsb pdb:4HFP|rcsb pdb:4HTC|rcsb pdb:4HZH|rcsb pdb:4I7Y|rcsb pdb:4LOY|rcsb pdb:4LXB|rcsb pdb:4LZ1|rcsb pdb:4LZ4|rcsb pdb:4MLF|rcsb pdb:4NZQ|rcsb pdb:4O03|rcsb pdb:4RKJ|rcsb pdb:4RKO|rcsb pdb:4RN6|rcsb pdb:4THN|rcsb pdb:4UD9|rcsb pdb:4UDW|rcsb pdb:4UE7|rcsb pdb:4UEH|rcsb pdb:4UFD|rcsb pdb:4UFE|rcsb pdb:4UFF|rcsb pdb:4UFG|rcsb pdb:4YES|rcsb pdb:5A2M|rcsb pdb:5AF9|rcsb pdb:5AFY|rcsb pdb:5AFZ|rcsb pdb:5AHG|rcsb pdb:5CMX|rcsb pdb:5DO4|rcsb pdb:5E8E|rcsb pdb:5EDK|rcsb pdb:5EDM|rcsb pdb:5EW1|rcsb pdb:5EW2|rcsb pdb:5GDS|rcsb pdb:5GIM|rcsb pdb:5JDU|rcsb pdb:5JFD|rcsb pdb:5JZY|rcsb pdb:5L6N|rcsb pdb:5MJT|rcsb pdb:5MLS|rcsb pdb:5MM6|rcsb pdb:5NHU|rcsb pdb:5TO3|rcsb pdb:5Z5W|rcsb pdb:5Z5X|rcsb pdb:6BJR|rcsb pdb:6C2W|rcsb pdb:6EO6|rcsb pdb:6EO7|rcsb pdb:6EO8|rcsb pdb:6EO9|rcsb pdb:6V5T|rcsb pdb:7KME|rcsb pdb:7TPP|rcsb pdb:8BWW|rcsb pdb:8KME|rcsb pdb:8UF7|rcsb pdb:9CTH|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-202733|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-416476|reactome:R-HSA-456926|reactome:R-HSA-76009|reactome:R-HSA-9657688|reactome:R-HSA-9672391|reactome:R-HSA-977606|refseq:NP_000497.1|refseq:NP_001298186.1|dip:DIP-6115N|efo:""Orphanet:325""|efo:""Orphanet:329217""|panther:PTHR24254(orthology-group)"	interpro:IPR014874(Staphylcoagulse-N)|interpro:IPR001443(Staphylocoagulase)|rcsb pdb:1NU7|rcsb pdb:1NU9|interpro:IPR043071|interpro:IPR043072	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:4B bottom panel|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/15	2024/11/14	rogid:f6OQ6v3WbFpxr7N6GhfZOHjSsTQ9606	rogid:aga3B8obxTGTXoLegjcxl/MIrDY1280	intact-crc:033D5084957A8250|rigid:NM/8xFacvvlontHXf3A0+Un73FI	false	-	sufficient binding region:1-325	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P18206	uniprotkb:Q6XVZ2	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	intact:EBI-7255868|intact:MINT-2842473	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	psi-mi:q6xvz2_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)	"psi-mi:""MI:0114""(x-ray crystallography)"	Hamiaux et al. (2006)	mint:MINT-5218803|pubmed:16826238|imex:IM-10964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8563178|mint:MINT-2842480|imex:IM-10964-2	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)|mint:MINT-2842482(identity)"	"interpro:IPR040658|interpro:IPR015138(Salmonella invasion protein A)|interpro:IPR023225|mint:Q6XVZ2|refseq:WP_005059309.1|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|rcsb pdb:2HSQ|mint:MINT-2842481(identity)"	-	"comment:""\""Stoichiometry: 1.0\"""""	"comment:mint|comment:""\""Stoichiometry: 1.0\"""""	figure legend:F1|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/04	2025/02/28	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	rogid:aC7VgMnktLLeAWbmm0FCl/CuQbQ623	intact-crc:0F08427E5F84493C|rigid:Ox186rtcV4JPmu+ad+AhgFvFrUQ	false	binding-associated region:2-258(MINT-2842491)	binding-associated region:560-633(MINT-2842515)	1	1	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6XVZ2	uniprotkb:P18206	intact:EBI-7255868|intact:MINT-2842473	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	psi-mi:q6xvz2_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	"psi-mi:""MI:0051""(fluorescence technology)"	Hamiaux et al. (2006)	mint:MINT-5218803|pubmed:16826238|imex:IM-10964	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8563239|mint:MINT-2842543|imex:IM-10964-3	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR040658|interpro:IPR015138(Salmonella invasion protein A)|interpro:IPR023225|mint:Q6XVZ2|refseq:WP_005059309.1|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|rcsb pdb:2HSQ|mint:MINT-2842551(identity)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)|mint:MINT-2842544(identity)"	-	"comment:mint|comment:""\""Stoichiometry: 1.0\"""""	"comment:""\""Stoichiometry: 1.0\"""""	figure legend:F2|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/04	2025/02/28	rogid:aC7VgMnktLLeAWbmm0FCl/CuQbQ623	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	intact-crc:57B7DE4D73853792|rigid:Ox186rtcV4JPmu+ad+AhgFvFrUQ	false	binding-associated region:560-633(MINT-2842556)	binding-associated region:1-250(MINT-2842545)	1	1	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P18206	uniprotkb:Q6XVZ2	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	intact:EBI-7255868|intact:MINT-2842473	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	psi-mi:q6xvz2_shifl(display_long)|uniprotkb:ipaA(gene name)|psi-mi:ipaA(display_short)	"psi-mi:""MI:0071""(molecular sieving)"	Hamiaux et al. (2006)	mint:MINT-5218803|pubmed:16826238|imex:IM-10964	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8563208|mint:MINT-2842518|imex:IM-10964-1	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)|mint:MINT-2842526(identity)"	"interpro:IPR040658|interpro:IPR015138(Salmonella invasion protein A)|interpro:IPR023225|mint:Q6XVZ2|refseq:WP_005059309.1|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|rcsb pdb:2HSQ|mint:MINT-2842519(identity)"	-	"comment:""\""Stoichiometry: 1.0\"""""	"comment:mint|comment:""\""Stoichiometry: 1.0\"""""	figure legend:F3|figure legend:SF1|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/04	2025/02/28	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	rogid:aC7VgMnktLLeAWbmm0FCl/CuQbQ623	intact-crc:E47DF80F19C409EC|rigid:Ox186rtcV4JPmu+ad+AhgFvFrUQ	false	binding-associated region:1-250(MINT-2842527)	binding-associated region:560-633(MINT-2842520)	1	1	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O52162	uniprotkb:Q15750	intact:EBI-8570450|intact:MINT-2842725	intact:EBI-358643|uniprotkb:Q2PP09|intact:EBI-3959873|uniprotkb:Q8IZW2|ensembl:ENSP00000216160.6	psi-mi:o52162_yeren(display_long)	psi-mi:tab1_human(display_long)|uniprotkb:TAB1(gene name)|psi-mi:TAB1(display_short)|uniprotkb:MAP3K7IP1(gene name synonym)|uniprotkb:TGF-beta-activated kinase 1-binding protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase 7-interacting protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Thiefes et al. (2006)	mint:MINT-5218828|pubmed:16845370|imex:IM-11373	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8570444|mint:MINT-2842701|imex:IM-11373-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016746""(acyltransferase activity)|refseq:WP_010891200.1|mint:O52162|interpro:IPR005083(Serine/Threonine acetyltransferase, YopJ)|mint:MINT-2842702(identity)"	"refseq:NP_006107.1|refseq:NP_705717.1|ensembl:ENSG00000100324.14(gene)|ensembl:ENST00000216160.11(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003279""(cardiac septum development)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0010008""(endosome membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030324""(lung development)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035904""(aorta development)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0048273""(mitogen-activated protein kinase p38 binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060976""(coronary vasculature development)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0141111""(positive regulation of cGAS/STING signaling pathway)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q15750|rcsb pdb:2J4O|rcsb pdb:2POM|rcsb pdb:2POP|rcsb pdb:2YDS|rcsb pdb:2YIY|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4GS6|rcsb pdb:4KA3|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5DIY|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5NZZ|rcsb pdb:5O90|rcsb pdb:5V5N|rcsb pdb:5VVU|rcsb pdb:7NTH|rcsb pdb:7NTI|rcsb pdb:8GW3|rcsb pdb:8XI8|reactome:R-HSA-168638|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-9705671|reactome:R-HSA-975163|dip:DIP-27524N|panther:PTHR13832(orthology-group)|mint:MINT-2842708(identity)"	-	"comment:mint|comment:""\""Stoichiometry: 1.0\"""""	"comment:""\""Stoichiometry: 1.0\"""""	figure legend:F5|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/04	2025/03/31	rogid:8BTTl/yicORTNcxztg3QkjBMS9E630	rogid:28+bzs6bpXJTun4XukxC/7oAYSs9606	intact-crc:911D44FF3BDC4EAD|rigid:+jdr6NbA5dqSnQZUIkhLyEelxy4	false	glutathione s tranferase tag:?-?(MINT-2842732)	myc tag:?-?(MINT-2842715)	1	1	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O52162	uniprotkb:P45985	intact:EBI-8570450|intact:MINT-2842725	intact:EBI-447868|uniprotkb:D3DTS5|uniprotkb:Q5U0B8|uniprotkb:B2R7N7|uniprotkb:B3KYB2|uniprotkb:Q6FHX4|uniprotkb:Q6P9H2|uniprotkb:Q6PIE6|ensembl:ENSP00000262445.5|intact:EBI-28973354	psi-mi:o52162_yeren(display_long)	psi-mi:mp2k4_human(display_long)|uniprotkb:JNK-activating kinase 1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase kinase 1(gene name synonym)|uniprotkb:SAPK/ERK kinase 1(gene name synonym)|uniprotkb:MAP2K4(gene name)|psi-mi:MAP2K4(display_short)|uniprotkb:JNKK1(gene name synonym)|uniprotkb:MKK4(gene name synonym)|uniprotkb:PRKMK4(gene name synonym)|uniprotkb:SERK1(gene name synonym)|uniprotkb:MEK4(gene name synonym)|uniprotkb:MAPK/ERK kinase 4(gene name synonym)|uniprotkb:SKK1(gene name synonym)|uniprotkb:SEK1(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Thiefes et al. (2006)	mint:MINT-5218828|pubmed:16845370|imex:IM-11373	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8570478|mint:MINT-2842738|imex:IM-11373-2	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016746""(acyltransferase activity)|refseq:WP_010891200.1|mint:O52162|interpro:IPR005083(Serine/Threonine acetyltransferase, YopJ)|mint:MINT-2842739(identity)"	"refseq:NP_003001.1|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0072709""(cellular response to sorbitol)|go:""GO:0090398""(cellular senescence)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|ensembl:ENSG00000065559.15(gene)|ensembl:ENST00000353533.10(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0008545""(JUN kinase kinase activity)|go:""GO:0009611""(response to wounding)|go:""GO:0030424""(axon)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034390""(smooth muscle cell apoptotic process)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036481""(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0043204""(perikaryon)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0051770""(obsolete positive regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061049""(cell growth involved in cardiac muscle cell development)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P45985|rcsb pdb:3ALN|rcsb pdb:3ALO|rcsb pdb:3VUT|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-5210891|reactome:R-HSA-5684264|refseq:NP_001268364.1|panther:PTHR48013(orthology-group)|ensembl:ENSP00000262445.5|ensembl:ENST00000415385.7|ensembl:ENSP00000410402.3|mint:MINT-2842746(identity)"	-	"comment:mint|comment:""\""Stoichiometry: 1.0\"""""	"comment:""\""Stoichiometry: 1.0\"""""	figure legend:F5|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/04	2025/03/31	rogid:8BTTl/yicORTNcxztg3QkjBMS9E630	rogid:/ndhkIbnc9oTm68r4DwDUyfXDF89606	intact-crc:309851F8AFF52859|rigid:Fzs3Do7CmwO9bod5uRhb/rkuYaw	false	glutathione s tranferase tag:?-?(MINT-2842743)	myc tag:?-?(MINT-2842751)	1	1	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5YB85	uniprotkb:P02452	intact:EBI-982988	intact:EBI-982999|uniprotkb:O76045|uniprotkb:P78441|uniprotkb:Q13896|uniprotkb:Q13902|uniprotkb:Q13903|uniprotkb:Q14037|uniprotkb:Q14992|uniprotkb:Q15176|uniprotkb:Q15201|uniprotkb:Q16050|uniprotkb:Q59F64|uniprotkb:Q7KZ30|uniprotkb:Q7KZ34|uniprotkb:Q8IVI5|uniprotkb:Q8N473|uniprotkb:Q9UML6|uniprotkb:Q9UMM7|ensembl:ENSP00000225964.6	psi-mi:q5yb85_strsg(display_long)	psi-mi:co1a1_human(display_long)|uniprotkb:Alpha-1 type I collagen(gene name synonym)|uniprotkb:COL1A1(gene name)|psi-mi:COL1A1(display_short)	"psi-mi:""MI:0049""(filter binding)"	Nitsche et al. (2006)	imex:IM-14490|pubmed:16278217	taxid:1320(strsg)|taxid:1320(Streptococcus sp. group G)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-983027|imex:IM-14490-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR019950|interpro:IPR003345(M protein repeat)|interpro:IPR049895|interpro:IPR049896|interpro:IPR019931|go:""GO:0005576""(extracellular region)"	"ensembl:ENSG00000108821.14(gene)|ensembl:ENST00000225964.10(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001503""(ossification)|go:""GO:0001568""(blood vessel development)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001957""(intramembranous ossification)|go:""GO:0001958""(endochondral ossification)|go:""GO:0002020""(protease binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005584""(collagen type I trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007601""(visual perception)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0015031""(protein transport)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030141""(secretory granule)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032355""(response to estradiol)|go:""GO:0032868""(response to insulin)|go:""GO:0032964""(collagen biosynthetic process)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034505""(tooth mineralization)|go:""GO:0038063""(collagen-activated tyrosine kinase receptor signaling pathway)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042802""(identical protein binding)|go:""GO:0043588""(skin development)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0048706""(embryonic skeletal system development)|go:""GO:0051591""(response to cAMP)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060346""(bone trabecula formation)|go:""GO:0060351""(cartilage development involved in endochondral bone morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071306""(cellular response to vitamin E)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:1902618""(cellular response to fluoride)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|mint:P02452|rcsb pdb:1Q7D|rcsb pdb:2LLP|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:5CVB|rcsb pdb:5K31|rcsb pdb:5OU8|rcsb pdb:5OU9|rcsb pdb:7E7B|rcsb pdb:7E7D|reactome:R-HSA-114604|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-8874081|reactome:R-HSA-8940973|reactome:R-HSA-8948216|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000079.2|dip:DIP-36077N|efo:""Orphanet:31112""|efo:""Orphanet:314029""|efo:""Orphanet:287""|efo:""Orphanet:1310""|efo:""Orphanet:1899""|efo:""Orphanet:216796""|efo:""Orphanet:216804""|efo:""Orphanet:216812""|efo:""Orphanet:216820""|efo:""Orphanet:230857""|panther:PTHR24023(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	comment:The FOG 1-C fragment lacking the COOH-terminal membrane anchor domain was used to minimize potential self-aggregation by hydrophobic interactions.|figure legend:2 A and Table 1|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/07	2025/02/28	rogid:zqO5BCkA1htFH0hZG6lRlWBvSCI1320	rogid:7tMYoZQIXMoLjRyYc/uiKYKCifY9606	intact-crc:EAE5C8BF77F0E55C|rigid:IfLFdusB5JQA+RtCRSiZ1KwrlF8	false	glutathione s tranferase tag:n-n|sufficient binding region:30-522|radiolabel:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:P08123	uniprotkb:Q5YB85	intact:EBI-983038|uniprotkb:P02464|uniprotkb:Q13897|uniprotkb:Q13997|uniprotkb:Q7Z5S6|uniprotkb:Q9UEB6|uniprotkb:Q9UEF9|uniprotkb:Q9UM83|uniprotkb:Q9UMI1|uniprotkb:Q9UML5|uniprotkb:Q9UMM6|uniprotkb:Q9UPH0|uniprotkb:Q13998|uniprotkb:Q14038|uniprotkb:Q14057|uniprotkb:Q15177|uniprotkb:Q15947|uniprotkb:Q16480|uniprotkb:Q16511|ensembl:ENSP00000297268.6	intact:EBI-982988	psi-mi:co1a2_human(display_long)|uniprotkb:Alpha-2 type I collagen(gene name synonym)|uniprotkb:COL1A2(gene name)|psi-mi:COL1A2(display_short)	psi-mi:q5yb85_strsg(display_long)	"psi-mi:""MI:0049""(filter binding)"	Nitsche et al. (2006)	imex:IM-14490|pubmed:16278217	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1320(strsg)|taxid:1320(Streptococcus sp. group G)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-983055|imex:IM-14490-2	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164692.19(gene)|ensembl:ENST00000297268.11(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001568""(blood vessel development)|go:""GO:0002020""(protease binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005584""(collagen type I trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030282""(bone mineralization)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032963""(collagen metabolic process)|go:""GO:0042476""(odontogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0046332""(SMAD binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070208""(protein heterotrimerization)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0085029""(extracellular matrix assembly)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|mint:P08123|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:6JEC|reactome:R-HSA-114604|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2173796|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-430116|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-8874081|reactome:R-HSA-8948216|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000080.2|dip:DIP-36079N|efo:""Orphanet:1899""|efo:""Orphanet:216796""|efo:""Orphanet:216804""|efo:""Orphanet:216812""|efo:""Orphanet:216820""|efo:""Orphanet:230851""|efo:""Orphanet:230857""|efo:""Orphanet:314029""|panther:PTHR24023(orthology-group)"	"interpro:IPR019950|interpro:IPR003345(M protein repeat)|interpro:IPR049895|interpro:IPR049896|interpro:IPR019931|go:""GO:0005576""(extracellular region)"	"psi-mi:""MI:0469""(intact)"	-	-	comment:The FOG 1-C fragment lacking the COOH-terminal membrane anchor domain was used to minimize potential self-aggregation by hydrophobic interactions.|figure legend:2 A and Table 1|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/07	2025/02/28	rogid:vRxr0tOWziIyQf9or1gC6sDlN8I9606	rogid:zqO5BCkA1htFH0hZG6lRlWBvSCI1320	intact-crc:AD0BF75C4F522119|rigid:m+hMZydU0ouB/DfMQ8vgFUFGITI	false	-	sufficient binding region:30-522|radiolabel:?-?|glutathione s tranferase tag:n-n	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q9ZFS5	intact:EBI-987754	intact:EBI-986955	-	psi-mi:q9zfs5_staau(display_long)|uniprotkb:set1(gene name)|psi-mi:set1(display_short)|uniprotkb:NCTC7878_00468(orf name)|uniprotkb:SAMEA1531725_02063(orf name)|uniprotkb:ERS329596_02063(orf name)	psi-mi:q569j1_human(display_short)|psi-mi:EBI-987754(display_long)|uniprotkb:IGHA1(gene name)|psi-mi:IGHA1(display_short)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Wines et al. (2006)	imex:IM-14492|pubmed:16293625	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-985594|imex:IM-14492-1	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000769829.1|rcsb pdb:1V1O|rcsb pdb:1V1P|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)|go:""GO:0005576""(extracellular region)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)"	uniprotkb:Q569J1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	"figure legend:1|kinetics:KD 6.8 plus or minus 0.8 E-9 M|comment:""\""The igha1 protein was fused to the human transferrin receptor (TfR).\""""|comment:The TfR-IgA Fc fusion protein was expressed in insect cells as a baculovirus expression vector was used.|caution:For the IgA1 Fc sequence the authors state there are two differences in sequence and have mapped L271M against the sequence corresponding to NG_001019 and R392H against the sequence corresponding to BC092449, which is a longer sequence.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/08	2024/11/14	rogid:wRzROcZsmUWT87giekpGNq1HpJs1280	rogid:+FgZJ0IBBJfh2rdkPSTOwC+qjBI9606	intact-crc:F4827295BC6C58D5|rigid:k+8W6TT8qI8zjheoGMb6dOQxnCU	false	-	fusion protein:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9ZFS5	intact:EBI-987754	intact:EBI-986955	-	psi-mi:q9zfs5_staau(display_long)|uniprotkb:set1(gene name)|psi-mi:set1(display_short)|uniprotkb:NCTC7878_00468(orf name)|uniprotkb:SAMEA1531725_02063(orf name)|uniprotkb:ERS329596_02063(orf name)	psi-mi:q569j1_human(display_short)|psi-mi:EBI-987754(display_long)|uniprotkb:IGHA1(gene name)|psi-mi:IGHA1(display_short)	"psi-mi:""MI:0054""(fluorescence-activated cell sorting)"	Wines et al. (2006)	imex:IM-14492|pubmed:16293625	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-987052|imex:IM-14492-2	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000769829.1|rcsb pdb:1V1O|rcsb pdb:1V1P|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)|go:""GO:0005576""(extracellular region)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)"	uniprotkb:Q569J1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	"figure legend:2 B and D, 4|comment:""\""The igha1 protein was fused to the human transferrin receptor (TfR).\""""|caution:For the IgA1 Fc sequence the authors state there are two differences in sequence and have mapped L271M against the sequence corresponding to NG_001019 and R392H against the sequence corresponding to BC092449, which is a longer sequence.|comment:The TfR-IgA Fc fusion protein was expressed in insect cells as a baculovirus expression vector was used.|comment:""\""The Fc region of the human IgA1 derived from Dakiki cells was fused to the N-terminal region of the transferrin receptor which is a type II integral membrane protein. This fusion protein was expressed on the surface of CHOP cells (CHO cells expressing the early genes of the polyoma virus).\""""|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/08	2024/11/14	rogid:wRzROcZsmUWT87giekpGNq1HpJs1280	rogid:+FgZJ0IBBJfh2rdkPSTOwC+qjBI9606	intact-crc:BB377C76FA7112B2|rigid:k+8W6TT8qI8zjheoGMb6dOQxnCU	false	-	mutation decreasing interaction:463-463|mutation decreasing interaction:278-278,279-279|mutation disrupting interaction:461-464|fusion protein:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6V4L5	uniprotkb:P00747	intact:EBI-984118	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:q6v4l5_strpy(display_long)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0405""(competition binding)"	Sanderson-Smith et al. (2006)	imex:IM-14501|pubmed:16319056	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-984104|imex:IM-14501-1	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR049895|interpro:IPR049896|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR021965|go:""GO:0005576""(extracellular region)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	"figure legend:Figure 3 Figure 4 Table 2|comment:The circulating form of plasminogen was isolated from Human plasma which has a Glutamic acid residue attached to the N-termini of the plasminogen protein.|kinetics:""\""Effective concentration of competitor (unlabelled Q6V4L5) required to inhibit binding by 50% (EC50) was 22.06 micro Molar.\""""|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/09	2024/11/14	rogid:p5i6BFFFDKWta1ql3AvDofxyd1w1314	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:46B8D3C4390069F8|rigid:gC179yZqrnFdjx2qMlH2vrFqde4	false	his tag:c-c	biotin tag:?-?|experimental feature:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6V4L9	uniprotkb:P00747	intact:EBI-984197	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:q6v4l9_strpy(display_long)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0405""(competition binding)"	Sanderson-Smith et al. (2006)	imex:IM-14501|pubmed:16319056	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-984208|imex:IM-14501-2	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR049895|interpro:IPR049896|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR003345(M protein repeat)|interpro:IPR021965|go:""GO:0005576""(extracellular region)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	"figure legend:Figure 3 Figure 4 Table 2|comment:The circulating form of plasminogen was isolated from Human plasma which has a Glutamic acid residue attached to the N-termini of the plasminogen protein.|kinetics:""\""Effective concentration of competitor (unlabelled Q6V4L9) required to inhibit binding by 50% (EC50) was 0.68 micro Molar.\""""|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/09	2024/11/14	rogid:3ys+HcZmTHyIIM3VaSCJaDUTR1E1314	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:58C2A1F79987C0DA|rigid:trgUs1/ADqLpqkiJIgNUMdIfF3Y	false	his tag:c-c	biotin tag:?-?|experimental feature:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00747	uniprotkb:Q6V4L4	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-984286	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:q6v4l4_strpy(display_long)	"psi-mi:""MI:0405""(competition binding)"	Sanderson-Smith et al. (2006)	imex:IM-14501|pubmed:16319056	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-984297|imex:IM-14501-3	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"interpro:IPR049895|interpro:IPR049896|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR021965|go:""GO:0005576""(extracellular region)"	"psi-mi:""MI:0469""(intact)"	-	-	"figure legend:Figure 3 Figure 4 Table 2|comment:The circulating form of plasminogen was isolated from Human plasma which has a Glutamic acid residue attached to the N-termini of the plasminogen protein.|kinetics:""\""Effective concentration of competitor (unlabelled  Q6V4L4) required to inhibit binding by 50% (EC50) was 1.96 micro Molar.\""""|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/09	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:3G94Ge5R75z91MX+oRVZCqSUk4o1314	intact-crc:893A79C1DD926056|rigid:f77HH30/NoDLLPnzoE2k5MgspWA	false	biotin tag:?-?|experimental feature:n-n	his tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00747	uniprotkb:Q6V4L1	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-984250	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:q6v4l1_strpy(display_long)	"psi-mi:""MI:0405""(competition binding)"	Sanderson-Smith et al. (2006)	imex:IM-14501|pubmed:16319056	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-984342|imex:IM-14501-4	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"interpro:IPR049895|interpro:IPR049896|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR003345(M protein repeat)|interpro:IPR021965|go:""GO:0005576""(extracellular region)"	"psi-mi:""MI:0469""(intact)"	-	-	"figure legend:Figure 3 Figure 4 Table 2|comment:The circulating form of plasminogen was isolated from Human plasma which has a Glutamic acid residue attached to the N-termini of the plasminogen protein.|kinetics:""\""Effective concentration of competitor (unlabelled  Q6V4L1) required to inhibit binding by 50% (EC50) was 0.81 micro Molar.\""""|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/09	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:tx0OppuORsf6ZuTXYnFyrc5b/0E1314	intact-crc:2D5BE5793607133F|rigid:adFw701Kr97BBgMb/WXsbcluf74	false	biotin tag:?-?|experimental feature:n-n	his tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6V4K9	uniprotkb:P00747	intact:EBI-984399	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:q6v4k9_strpy(display_long)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0405""(competition binding)"	Sanderson-Smith et al. (2006)	imex:IM-14501|pubmed:16319056	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-984408|imex:IM-14501-5	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR049895|interpro:IPR049896|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR021965|go:""GO:0005576""(extracellular region)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	"figure legend:Figure 3 Figure 4 Table 2|comment:The circulating form of plasminogen was isolated from Human plasma which has a Glutamic acid residue attached to the N-termini of the plasminogen protein.|kinetics:""\""Effective concentration of competitor (unlabelled  Q6V4K9) required to inhibit binding by 50% (EC50) was 5.77 micro Molar.\""""|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/09	2024/11/14	rogid:dXLl0BwN3F94sVdoolwrLpWLsKs1314	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:20EF254E4BD3BD0B|rigid:oTqqpLfIV1dg79nvpth3x6S4Kg0	false	his tag:c-c	biotin tag:?-?|experimental feature:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6V4L5	uniprotkb:P00747	intact:EBI-984118	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:q6v4l5_strpy(display_long)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0049""(filter binding)"	Sanderson-Smith et al. (2006)	imex:IM-14501|pubmed:16319056	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-984184|imex:IM-14501-6	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR049895|interpro:IPR049896|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR021965|go:""GO:0005576""(extracellular region)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Figure 2C|comment:The circulating form of plasminogen was isolated from Human plasma which has a Glutamic acid residue attached to the N-termini of the plasminogen protein.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/09	2024/11/14	rogid:p5i6BFFFDKWta1ql3AvDofxyd1w1314	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:E1DB04808CD249D5|rigid:gC179yZqrnFdjx2qMlH2vrFqde4	false	his tag:c-c|glutathione s tranferase tag:n-n	biotin tag:?-?|experimental feature:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00747	uniprotkb:Q6V4L9	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-984197	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:q6v4l9_strpy(display_long)	"psi-mi:""MI:0049""(filter binding)"	Sanderson-Smith et al. (2006)	imex:IM-14501|pubmed:16319056	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-984232|imex:IM-14501-7	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"interpro:IPR049895|interpro:IPR049896|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR003345(M protein repeat)|interpro:IPR021965|go:""GO:0005576""(extracellular region)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Figure 2C|comment:The circulating form of plasminogen was isolated from Human plasma which has a Glutamic acid residue attached to the N-termini of the plasminogen protein.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/09	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:3ys+HcZmTHyIIM3VaSCJaDUTR1E1314	intact-crc:E7D92F9E0387C263|rigid:trgUs1/ADqLpqkiJIgNUMdIfF3Y	false	biotin tag:?-?|experimental feature:n-n	glutathione s tranferase tag:n-n|his tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00747	uniprotkb:Q6V4L1	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-984250	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:q6v4l1_strpy(display_long)	"psi-mi:""MI:0049""(filter binding)"	Sanderson-Smith et al. (2006)	imex:IM-14501|pubmed:16319056	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-984263|imex:IM-14501-8	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"interpro:IPR049895|interpro:IPR049896|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR003345(M protein repeat)|interpro:IPR021965|go:""GO:0005576""(extracellular region)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Figure 2C|comment:The circulating form of plasminogen was isolated from Human plasma which has a Glutamic acid residue attached to the N-termini of the plasminogen protein.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/09	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:tx0OppuORsf6ZuTXYnFyrc5b/0E1314	intact-crc:73DAE27509E130B8|rigid:adFw701Kr97BBgMb/WXsbcluf74	false	biotin tag:?-?|experimental feature:n-n	glutathione s tranferase tag:n-n|his tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00747	uniprotkb:Q6V4L4	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-984286	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:q6v4l4_strpy(display_long)	"psi-mi:""MI:0049""(filter binding)"	Sanderson-Smith et al. (2006)	imex:IM-14501|pubmed:16319056	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1314(strpy)|taxid:1314(Streptococcus pyogenes)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-984320|imex:IM-14501-9	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"interpro:IPR049895|interpro:IPR049896|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR021965|go:""GO:0005576""(extracellular region)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Figure 2C|comment:The circulating form of plasminogen was isolated from Human plasma which has a Glutamic acid residue attached to the N-termini of the plasminogen protein.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/09	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:3G94Ge5R75z91MX+oRVZCqSUk4o1314	intact-crc:A95B7D3DED9E978E|rigid:f77HH30/NoDLLPnzoE2k5MgspWA	false	biotin tag:?-?|experimental feature:n-n	glutathione s tranferase tag:n-n|his tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02976	uniprotkb:P02741	intact:EBI-7340383|intact:MINT-1206155|psi-mi:MINT-5231072|uniprotkb:Q2G1N8	intact:EBI-1395983|ensembl:ENSP00000255030.5|uniprotkb:A8K078|uniprotkb:Q08AK3|uniprotkb:Q8WW75|uniprotkb:D3DVD9|uniprotkb:D3DVE0	psi-mi:spa_staa8(display_long)|uniprotkb:spa(gene name)|psi-mi:spa(display_short)|uniprotkb:SAOUHSC_00069(locus name)|uniprotkb:Staphylococcal protein A(gene name synonym)	psi-mi:crp_human(display_long)|uniprotkb:CRP(gene name)|psi-mi:CRP(display_short)|uniprotkb:PTX1(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Das et al. (2004)	pubmed:15474020|imex:IM-13907|mint:MINT-5217226	"taxid:93061(staa8)|taxid:93061(""Staphylococcus aureus (strain NCTC 8325)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7340408|mint:MINT-50620|imex:IM-13907-1	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P02976|interpro:IPR018392|refseq:YP_498670.1|interpro:IPR003132(Protein A, Ig-binding)|interpro:IPR005038(Octapeptide repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR009063(Immunoglobulin/albumin-binding)|refseq:WP_000728764.1|interpro:IPR036779|interpro:IPR019931|go:""GO:0005576""(extracellular region)|go:""GO:0019864""(IgG binding)|rcsb pdb:1DEE|rcsb pdb:4Y4Y|rcsb pdb:4Y5Z|rcsb pdb:5U3D|rcsb pdb:5U4Y|rcsb pdb:5U5F|rcsb pdb:5U5M|rcsb pdb:5U6A|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6K3M|rcsb pdb:6K64|rcsb pdb:6K65|rcsb pdb:6K68|rcsb pdb:6K6A|rcsb pdb:6K6B|rcsb pdb:6SOW|rcsb pdb:8DA3|rcsb pdb:8DA4|rcsb pdb:8DA5|rcsb pdb:8DA6|rcsb pdb:8DA7|rcsb pdb:8DA8|rcsb pdb:8DA9|rcsb pdb:8DAA|rcsb pdb:8DAB|rcsb pdb:8DAC|mint:MINT-1206199(identity)"	"ensembl:ENSG00000132693.12(gene)|ensembl:ENST00000255030.9(transcript)|go:""GO:0001849""(complement component C1q complex binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006953""(acute-phase response)|go:""GO:0006954""(inflammatory response)|go:""GO:0008228""(opsonization)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010745""(negative regulation of macrophage derived foam cell differentiation)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0030169""(low-density lipoprotein particle binding)|go:""GO:0032677""(regulation of interleukin-8 production)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0032945""(negative regulation of mononuclear cell proliferation)|go:""GO:0033265""(choline binding)|go:""GO:0042310""(vasoconstriction)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|interpro:IPR051005|mint:P02741|rcsb pdb:1B09|rcsb pdb:1GNH|rcsb pdb:1LJ7|rcsb pdb:3L2Y|rcsb pdb:3PVN|rcsb pdb:3PVO|rcsb pdb:7PK9|rcsb pdb:7PKB|rcsb pdb:7PKD|rcsb pdb:7PKE|rcsb pdb:7PKF|rcsb pdb:7PKG|rcsb pdb:7PKH|rcsb pdb:7TBA|rcsb pdb:8WV4|rcsb pdb:8WV5|reactome:R-HSA-173623|refseq:NP_000558.2|refseq:NP_001315986.1|refseq:NP_001315987.1|dip:DIP-39125N|panther:PTHR45869(orthology-group)|mint:MINT-1206205(identity)"	-	"comment:mint|comment:""\""Stoichiometry: 1.0\"""""	"comment:""\""Stoichiometry: 1.0\"""""	"figure legend:F3|comment:""\""SHORTLABEL: it's an ELISA\""""|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/12/02	2024/11/14	rogid:m02uruh6f2k4nBjFlfu+Eu1IcRs93061	rogid:R7vKMSGKD4ETbUKVGL9IiL8jzjE9606	intact-crc:00CD7D6DFE0D33A1|rigid:l+v9jWXl4oC8RLrzIflkTuU2QtI	false	tag:?-?(MINT-1206200)	-	-	-	"psi-mi:""MI:0086""(polyclonal antibody western blot)"	"psi-mi:""MI:0086""(polyclonal antibody western blot)"
uniprotkb:Q9GZQ8	uniprotkb:P50335	intact:EBI-373144|uniprotkb:Q6NW02|ensembl:ENSP00000268607.5|ensembl:ENSP00000498476.1|intact:EBI-28979688	intact:EBI-42490111	psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym)|uniprotkb:Microtubule-associated proteins 1A/1B light chain 3B(gene name synonym)	psi-mi:yhjj_salty(display_long)|uniprotkb:yhjJ(gene name)|psi-mi:yhjJ(display_short)|uniprotkb:STM3613(locus name)	"psi-mi:""MI:0096""(pull down)"	Sudhakar et al. (2019)	pubmed:30909843|imex:IM-29742	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-42490109|imex:IM-29742-1	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_073729.1|ensembl:ENSG00000140941.14(gene)|ensembl:ENST00000268607.10(transcript)|ensembl:ENST00000650688.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0000423""(mitophagy)|go:""GO:0005739""(mitochondrion)|go:""GO:0005776""(autophagosome)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005930""(axoneme)|go:""GO:0006914""(autophagy)|go:""GO:0006995""(cellular response to nitrogen starvation)|go:""GO:0008017""(microtubule binding)|go:""GO:0008429""(phosphatidylethanolamine binding)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0012505""(endomembrane system)|go:""GO:0016236""(macroautophagy)|go:""GO:0031090""(organelle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0097001""(ceramide binding)|go:""GO:0097352""(autophagosome maturation)|interpro:IPR004241(""Light chain 3 (LC3)"")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:3VTV|rcsb pdb:2ZJD|rcsb pdb:3VTW|rcsb pdb:3VTU|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|rcsb pdb:7ELG|rcsb pdb:7GA8|rcsb pdb:7GA9|rcsb pdb:7GAA|rcsb pdb:7GAB|rcsb pdb:7GAC|rcsb pdb:7GAD|rcsb pdb:7GAE|rcsb pdb:7GAF|rcsb pdb:7GAG|rcsb pdb:7GAH|rcsb pdb:7GAI|rcsb pdb:7GAJ|rcsb pdb:7GAK|rcsb pdb:7GAL|rcsb pdb:7GAM|rcsb pdb:7GAN|rcsb pdb:7GAO|rcsb pdb:7GAP|rcsb pdb:7GAQ|rcsb pdb:7GAR|rcsb pdb:7GAS|rcsb pdb:7GAU|rcsb pdb:8Q53|rcsb pdb:8Q7K|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|reactome:R-HSA-9754560|reactome:R-HSA-9755511|dip:DIP-29760N|panther:PTHR10969(orthology-group)"	"mint:P50335|refseq:NP_462514.1|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0042597""(periplasmic space)|go:""GO:0046872""(metal ion binding)|panther:PTHR43690(orthology-group)|interpro:IPR050626|refseq:WP_001163182.1|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR007863(Peptidase M16, C-terminal)"	-	-	-	figure legend:fig. 4 a,b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2023/04/18	2025/01/08	rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606	rogid:yPJh5qjmLWYoMs1ncWscq0Janxc99287	intact-crc:448D11B91233AEF0|rigid:lEcq9OArlih7XHXmg/Z4R0ytg6A	false	glutathione s tranferase tag:?-?	his tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:O14763	uniprotkb:P0DUJ7	intact:EBI-518882|uniprotkb:Q6UXM8|uniprotkb:Q7Z360|uniprotkb:O14720|uniprotkb:O15508|uniprotkb:O15517|uniprotkb:O15531|uniprotkb:Q9BVE0|ensembl:ENSP00000276431.4	intact:EBI-42494616	psi-mi:tr10b_human(display_long)|uniprotkb:Death receptor 5(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 2(gene name synonym)|uniprotkb:UNQ160/PRO186(orf name)|uniprotkb:TNFRSF10B(gene name)|psi-mi:TNFRSF10B(display_short)|uniprotkb:DR5(gene name synonym)|uniprotkb:KILLER(gene name synonym)|uniprotkb:TRAILR2(gene name synonym)|uniprotkb:TRICK2(gene name synonym)|uniprotkb:ZTNFR9(gene name synonym)	psi-mi:ssek3_salts(display_long)|uniprotkb:sseK3(gene name)|psi-mi:sseK3(display_short)|uniprotkb:Salmonella secreted effector K3(gene name synonym)|uniprotkb:SL1344_1928(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Newson et al. (2019)	imex:IM-29759|pubmed:30902834	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-42494614|imex:IM-29759-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:494547""|efo:""Orphanet:494550""|efo:""Orphanet:500464""|efo:""Orphanet:500478""|efo:""Orphanet:500481""|efo:""Orphanet:502363""|efo:""Orphanet:502366""|ensembl:ENSG00000120889.13(gene)|ensembl:ENST00000276431.9(transcript)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007250""(activation of NF-kappaB-inducing kinase activity)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009986""(cell surface)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0036463""(TRAIL receptor activity)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045569""(TRAIL binding)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0071260""(cellular response to mechanical stimulus)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|interpro:IPR052491|mint:O14763|rcsb pdb:1D0G|rcsb pdb:1D4V|rcsb pdb:1DU3|rcsb pdb:1ZA3|rcsb pdb:2H9G|rcsb pdb:3X3F|rcsb pdb:4I9X|rcsb pdb:4N90|rcsb pdb:4OD2|rcsb pdb:6NHW|rcsb pdb:6NHY|rcsb pdb:6T3J|rcsb pdb:8DPX|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|refseq:NP_003833.4|refseq:NP_671716.2|dip:DIP-33566N|panther:PTHR46330(orthology-group)"	"mint:P0DUJ7|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0030145""(manganese ion binding)|go:""GO:0034053""(obsolete symbiont-mediated perturbation of host defense-related programmed cell death)|go:""GO:0043657""(host cell)|go:""GO:0044177""(host cell Golgi apparatus)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6CGI|rcsb pdb:6DUS|rcsb pdb:6EYR|rcsb pdb:6EYT|refseq:WP_000492926.1"	-	-	-	figure legend:fig. 5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/05/08	2024/11/14	rogid:V021Tohje+gkHyYH6iOOnN/IBJ49606	rogid:h37KSGoIrBoGPZmHVr5lbkxjGXE216597	intact-crc:A5563DA830FC4735|rigid:Q1iMG/aZqTmriCT2dqQJVDzLkhs	false	flag tag:n-n|binding-associated region:339-422	green fluorescent protein tag:?-?|mutation disrupting interaction:258-258	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P0DUJ7	uniprotkb:Q15628	intact:EBI-42494616	intact:EBI-359215|uniprotkb:Q52NZ1|uniprotkb:B2RDS3|uniprotkb:B3KQZ9|ensembl:ENSP00000341268.4	psi-mi:ssek3_salts(display_long)|uniprotkb:sseK3(gene name)|psi-mi:sseK3(display_short)|uniprotkb:Salmonella secreted effector K3(gene name synonym)|uniprotkb:SL1344_1928(locus name)	psi-mi:tradd_human(display_long)|uniprotkb:TRADD(gene name)|psi-mi:TRADD(display_short)|uniprotkb:TNFRSF1A-associated via death domain(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Newson et al. (2019)	imex:IM-29759|pubmed:30902834	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-42494649|imex:IM-29759-3	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P0DUJ7|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0030145""(manganese ion binding)|go:""GO:0034053""(obsolete symbiont-mediated perturbation of host defense-related programmed cell death)|go:""GO:0043657""(host cell)|go:""GO:0044177""(host cell Golgi apparatus)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|rcsb pdb:6CGI|rcsb pdb:6DUS|rcsb pdb:6EYR|rcsb pdb:6EYT|refseq:WP_000492926.1"	"panther:PTHR14913(orthology-group)|refseq:NP_003780.1|refseq:NP_001310481.1|refseq:XP_005256270.1|refseq:XP_016879304.1|dip:DIP-285N|ensembl:ENSG00000102871.16(gene)|ensembl:ENST00000345057.9(transcript)|go:""GO:0002947""(tumor necrosis factor receptor superfamily complex)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051798""(positive regulation of hair follicle development)|go:""GO:0070513""(death domain binding)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR009095(TRADD, N-terminal)|interpro:IPR011029(DEATH-like)|interpro:IPR035712|interpro:IPR036729|mint:Q15628|rcsb pdb:1F2H|rcsb pdb:1F3V|rcsb pdb:5XME|rcsb pdb:6AC0|rcsb pdb:7CSQ|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9693928"	-	-	-	figure legend:fig. 6|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/05/08	2025/03/26	rogid:h37KSGoIrBoGPZmHVr5lbkxjGXE216597	rogid:waTMnn0uXSbf7bracJUScX9ckEc9606	intact-crc:6F8BAB581ABAF640|rigid:2ogWpILzVchgE+oyAtycf0+QyZc	false	green fluorescent protein tag:?-?|mutation disrupting interaction:258-258	flag tag:n-n|binding-associated region:179-289	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P00811	wwpdb:7P2P	intact:EBI-1134803|uniprotkb:Q2M6F2	intact:EBI-9026864|emdb:EMD-13171|intenz:3.4.21.89	psi-mi:ampc_ecoli(display_long)|uniprotkb:Cephalosporinase(gene name synonym)|uniprotkb:ampC(gene name)|psi-mi:ampC(display_short)|uniprotkb:ampA(gene name synonym)|uniprotkb:b4150(locus name)|uniprotkb:JW4111(locus name)	"psi-mi:spc_human(display_short)|psi-mi:7P2P(display_long)|intact:Signal peptidase complex, SEC11A variant(complex recommended name)|intact:""SEC11A:SPCS1:SPCS2:SPCS3""(complex systematic name)"	"psi-mi:""MI:0435""(protease assay)"	Liaci et al. (2021)	pubmed:34388369|imex:IM-29326	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0570""(protein cleavage)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-27117168|imex:IM-29326-17	intact-miscore:0.44	-	"psi-mi:""MI:1343""(enzyme regulator)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:1302""(stable complex)"	"rcsb pdb:4JXS|rcsb pdb:4JXV|rcsb pdb:4JXW|rcsb pdb:4KZ3|rcsb pdb:4KZ4|rcsb pdb:4KZ5|rcsb pdb:4KZ6|rcsb pdb:4KZ7|rcsb pdb:4KZ8|rcsb pdb:4KZ9|rcsb pdb:4KZA|rcsb pdb:4KZB|refseq:NP_418574.1|interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR001586(Beta-lactamase, class C active site)|rcsb pdb:1C3B|rcsb pdb:1FCM|rcsb pdb:1FCN|rcsb pdb:1FCO|rcsb pdb:1FSW|rcsb pdb:1FSY|rcsb pdb:1GA9|rcsb pdb:1I5Q|rcsb pdb:1IEL|rcsb pdb:1IEM|rcsb pdb:1KDS|rcsb pdb:1KDW|rcsb pdb:1KE0|rcsb pdb:1KE3|rcsb pdb:1KE4|rcsb pdb:1KVL|rcsb pdb:1KVM|rcsb pdb:1L0D|rcsb pdb:1L0E|rcsb pdb:4OKP|rcsb pdb:4OLD|rcsb pdb:1L0F|rcsb pdb:1L0G|rcsb pdb:1L2S|rcsb pdb:1LL5|rcsb pdb:1LL9|rcsb pdb:1LLB|rcsb pdb:1MXO|rcsb pdb:1MY8|rcsb pdb:1O07|rcsb pdb:1PI4|rcsb pdb:1PI5|rcsb pdb:1XGI|rcsb pdb:1XGJ|rcsb pdb:2BLS|rcsb pdb:2FFY|rcsb pdb:2HDQ|rcsb pdb:2HDR|rcsb pdb:2HDS|rcsb pdb:2HDU|rcsb pdb:2I72|rcsb pdb:2P9V|rcsb pdb:2PU2|rcsb pdb:2PU4|rcsb pdb:2R9W|rcsb pdb:2R9X|rcsb pdb:2RCX|rcsb pdb:3BLS|rcsb pdb:3BM6|rcsb pdb:3FKV|rcsb pdb:3FKW|rcsb pdb:3GQZ|rcsb pdb:3GR2|rcsb pdb:3GRJ|rcsb pdb:3GSG|rcsb pdb:3GTC|rcsb pdb:3GV9|rcsb pdb:3GVB|rcsb pdb:3IWI|rcsb pdb:3IWO|rcsb pdb:3IWQ|rcsb pdb:3IXB|rcsb pdb:3IXD|rcsb pdb:3IXG|rcsb pdb:3IXH|rcsb pdb:3O86|rcsb pdb:3O87|rcsb pdb:3O88|rcsb pdb:4OLG|rcsb pdb:4E3I|rcsb pdb:4E3J|rcsb pdb:4E3K|rcsb pdb:4E3L|rcsb pdb:4E3M|rcsb pdb:4E3N|rcsb pdb:4E3O|rcsb pdb:6T3D|rcsb pdb:6YEN|rcsb pdb:6YEO|rcsb pdb:6YPD|rcsb pdb:6DPT|rcsb pdb:6DPX|rcsb pdb:6DPY|rcsb pdb:9C6P|rcsb pdb:9C81|rcsb pdb:9C83|rcsb pdb:9C84|rcsb pdb:4LV0|rcsb pdb:4LV1|rcsb pdb:4LV2|rcsb pdb:4LV3|rcsb pdb:6DPZ|rcsb pdb:4JXG|rcsb pdb:4KEN|rcsb pdb:4KG2|rcsb pdb:4KG5|rcsb pdb:4KG6|panther:PTHR46825(orthology-group)|refseq:WP_001336292.1|rcsb pdb:6T5Y|rcsb pdb:6T7L|rcsb pdb:6TBW|rcsb pdb:6TPM|rcsb pdb:6T35|go:""GO:0008800""(beta-lactamase activity)|go:""GO:0017001""(antibiotic catabolic process)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0046677""(response to antibiotic)|rcsb pdb:9DHL|interpro:IPR050491|rcsb pdb:5JOC|rcsb pdb:6WHF|rcsb pdb:6X9Y|rcsb pdb:6XG1|rcsb pdb:6XFS"	"go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|complex portal:CPX-2847(complex-primary)|intact:EBI-27112849(exp-evidence)|evidence ontology:""ECO:0000353""|pubmed:34388369(see-also)|go:""GO:0006465""(signal peptide processing)|go:""GO:0005787""(signal peptidase complex)|reactome:R-HSA-264960(see-also)"	-	-	"complex-properties:""\""SEC11 interacts with SPCS3 to form a globular luminal body consisting solely of beta sheets. The transmembrane domains of SPC2 and SEC11 on one side and SPCS1 and SPCS3 on the other form two distinct three-helix bundles, which frame a characteristic 15A-wide, lipid-filled window in the membrane.  SPCS1 and SPCS2 form a clamp-like structure that orients the transmembrane segments of SEC11 and SPCS3. Substrate selectivity is achieved through the combination of two key binding determinants - a shallow, hydrophobic signal peptide scissile region-binding pocket and membrane shaping by the complex which only allows allows signal peptides. with short a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids to diffuse into the transmembrane window and to access the c-region-binding pocket,\""""|complex-assembly:Heterotetramer|curated-complex:""\""Catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. The complex cleaves the signal peptides of most secretory and many membrane proteins as soon as the lumenal domain of the translocating polypeptide is large enough to expose its cleavage site to the enzyme, during the translocation of the protein through the translocon pore into the endoplasmic reticulum. The complex specifically cleaves N- terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids\"""""	figure legend:Fig. 1D, 4B, 7N|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/28	2024/11/14	rogid:pWZ8uTHmgbg7fRMML3qvvhjTTa883333	-	intact-crc:678C93D25B8EF776	false	-	mutation decreasing interaction rate:97-97,116-116|mutation decreasing interaction rate:116-116|mutation with no effect:121-121|mutation disrupting interaction rate:122-122|necessary binding region:166..166-179|mutation disrupting interaction rate:56-56	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P00811	wwpdb:7p2q	intact:EBI-1134803|uniprotkb:Q2M6F2	intact:EBI-27113052|emdb:EMD-13172	psi-mi:ampc_ecoli(display_long)|uniprotkb:Cephalosporinase(gene name synonym)|uniprotkb:ampC(gene name)|psi-mi:ampC(display_short)|uniprotkb:ampA(gene name synonym)|uniprotkb:b4150(locus name)|uniprotkb:JW4111(locus name)	"psi-mi:spc_human-1(display_short)|psi-mi:7p2q(display_long)|intact:""SEC11C:SPCS1:SPCS2:SPCS3""(complex systematic name)|intact:Signal peptidase complex, SEC11C variant(complex recommended name)"	"psi-mi:""MI:0435""(protease assay)"	Liaci et al. (2021)	pubmed:34388369|imex:IM-29326	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0570""(protein cleavage)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-27120001|imex:IM-29326-19	intact-miscore:0.44	-	"psi-mi:""MI:1343""(enzyme regulator)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:1302""(stable complex)"	"rcsb pdb:4JXS|rcsb pdb:4JXV|rcsb pdb:4JXW|rcsb pdb:4KZ3|rcsb pdb:4KZ4|rcsb pdb:4KZ5|rcsb pdb:4KZ6|rcsb pdb:4KZ7|rcsb pdb:4KZ8|rcsb pdb:4KZ9|rcsb pdb:4KZA|rcsb pdb:4KZB|refseq:NP_418574.1|interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR001586(Beta-lactamase, class C active site)|rcsb pdb:1C3B|rcsb pdb:1FCM|rcsb pdb:1FCN|rcsb pdb:1FCO|rcsb pdb:1FSW|rcsb pdb:1FSY|rcsb pdb:1GA9|rcsb pdb:1I5Q|rcsb pdb:1IEL|rcsb pdb:1IEM|rcsb pdb:1KDS|rcsb pdb:1KDW|rcsb pdb:1KE0|rcsb pdb:1KE3|rcsb pdb:1KE4|rcsb pdb:1KVL|rcsb pdb:1KVM|rcsb pdb:1L0D|rcsb pdb:1L0E|rcsb pdb:4OKP|rcsb pdb:4OLD|rcsb pdb:1L0F|rcsb pdb:1L0G|rcsb pdb:1L2S|rcsb pdb:1LL5|rcsb pdb:1LL9|rcsb pdb:1LLB|rcsb pdb:1MXO|rcsb pdb:1MY8|rcsb pdb:1O07|rcsb pdb:1PI4|rcsb pdb:1PI5|rcsb pdb:1XGI|rcsb pdb:1XGJ|rcsb pdb:2BLS|rcsb pdb:2FFY|rcsb pdb:2HDQ|rcsb pdb:2HDR|rcsb pdb:2HDS|rcsb pdb:2HDU|rcsb pdb:2I72|rcsb pdb:2P9V|rcsb pdb:2PU2|rcsb pdb:2PU4|rcsb pdb:2R9W|rcsb pdb:2R9X|rcsb pdb:2RCX|rcsb pdb:3BLS|rcsb pdb:3BM6|rcsb pdb:3FKV|rcsb pdb:3FKW|rcsb pdb:3GQZ|rcsb pdb:3GR2|rcsb pdb:3GRJ|rcsb pdb:3GSG|rcsb pdb:3GTC|rcsb pdb:3GV9|rcsb pdb:3GVB|rcsb pdb:3IWI|rcsb pdb:3IWO|rcsb pdb:3IWQ|rcsb pdb:3IXB|rcsb pdb:3IXD|rcsb pdb:3IXG|rcsb pdb:3IXH|rcsb pdb:3O86|rcsb pdb:3O87|rcsb pdb:3O88|rcsb pdb:4OLG|rcsb pdb:4E3I|rcsb pdb:4E3J|rcsb pdb:4E3K|rcsb pdb:4E3L|rcsb pdb:4E3M|rcsb pdb:4E3N|rcsb pdb:4E3O|rcsb pdb:6T3D|rcsb pdb:6YEN|rcsb pdb:6YEO|rcsb pdb:6YPD|rcsb pdb:6DPT|rcsb pdb:6DPX|rcsb pdb:6DPY|rcsb pdb:9C6P|rcsb pdb:9C81|rcsb pdb:9C83|rcsb pdb:9C84|rcsb pdb:4LV0|rcsb pdb:4LV1|rcsb pdb:4LV2|rcsb pdb:4LV3|rcsb pdb:6DPZ|rcsb pdb:4JXG|rcsb pdb:4KEN|rcsb pdb:4KG2|rcsb pdb:4KG5|rcsb pdb:4KG6|panther:PTHR46825(orthology-group)|refseq:WP_001336292.1|rcsb pdb:6T5Y|rcsb pdb:6T7L|rcsb pdb:6TBW|rcsb pdb:6TPM|rcsb pdb:6T35|go:""GO:0008800""(beta-lactamase activity)|go:""GO:0017001""(antibiotic catabolic process)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0046677""(response to antibiotic)|rcsb pdb:9DHL|interpro:IPR050491|rcsb pdb:5JOC|rcsb pdb:6WHF|rcsb pdb:6X9Y|rcsb pdb:6XG1|rcsb pdb:6XFS"	"go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|intact:EBI-27112857(exp-evidence)|evidence ontology:""ECO:0000353""|pubmed:34388369(see-also)|go:""GO:0006465""(signal peptide processing)|go:""GO:0005787""(signal peptidase complex)|reactome:R-HSA-264960(see-also)|complex portal:CPX-7205(complex-primary)"	-	-	"complex-properties:""\""SEC11 interacts with SPCS3 to form a globular luminal body consisting solely of beta sheets. The transmembrane domains of SPC2 and SEC11 on one side and SPCS1 and SPCS3 on the other form two distinct three-helix bundles, which frame a characteristic 15A-wide, lipid-filled window in the membrane.  SPCS1 and SPCS2 form a clamp-like structure that orients the transmembrane segments of SEC11 and SPCS3. Substrate selectivity is achieved through the combination of two key binding determinants - a shallow, hydrophobic signal peptide scissile region-binding pocket and membrane shaping by the complex which only allows allows signal peptides. with short a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids to diffuse into the transmembrane window and to access the c-region-binding pocket,\""""|complex-assembly:Heterotetramer|curated-complex:""\""Catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. The complex cleaves the signal peptides of most secretory and many membrane proteins as soon as the lumenal domain of the translocating polypeptide is large enough to expose its cleavage site to the enzyme, during the translocation of the protein through the translocon pore into the endoplasmic reticulum. The complex specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids\"""""	figure legend:Fig. 1D, 4B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/28	2024/11/14	rogid:pWZ8uTHmgbg7fRMML3qvvhjTTa883333	-	intact-crc:76F51B8FADA6BF83	false	-	mutation decreasing interaction rate:109-109,128-128|mutation decreasing interaction rate:128-128|mutation with no effect:133-133|mutation disrupting interaction rate:134-134|mutation disrupting interaction rate:68-68|necessary binding region:178..178-192	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:C8UFK8	uniprotkb:P16333	intact:EBI-28952948	intact:EBI-389883|uniprotkb:B7Z751|intact:EBI-3448658|uniprotkb:D3DNE3|ensembl:ENSP00000288986.2|ensembl:ENSP00000417273.1	psi-mi:tir_eco1a(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:ECO111_3745(locus name)|uniprotkb:Secreted effector protein Tir(gene name synonym)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:Cytoplasmic protein NCK1(gene name synonym)|uniprotkb:NCK adapter protein 1(gene name synonym)|uniprotkb:SH2/SH3 adapter protein NCK-alpha(gene name synonym)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Kliche et al. (2021)	pubmed:33436498|imex:IM-29390	"taxid:585396(""Escherichia coli O111:H- (strain 11128 / EHEC)"")|taxid:585396(""Escherichia coli O111:H- (strain 11128 / EHEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-28952935|imex:IM-29390-25	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|refseq:WP_001369484.1|interpro:IPR037003|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633"	"refseq:NP_001177725.1|refseq:NP_006144.1|refseq:NP_001278928.1|ensembl:ENSG00000158092.7(gene)|ensembl:ENST00000288986.6(transcript)|ensembl:ENST00000481752.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007015""(actin filament organization)|go:""GO:0007172""(signal complex assembly)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036493""(positive regulation of translation in response to endoplasmic reticulum stress)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0071074""(eukaryotic initiation factor eIF2 binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903676""(positive regulation of cap-dependent translational initiation)|go:""GO:1903679""(positive regulation of cap-independent translational initiation)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1903912""(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|interpro:IPR051184|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-9833482|reactome:R-HSA-983695|dip:DIP-639N|panther:PTHR19969(orthology-group)"	-	-	-	figure legend:3A, Table 2|curation depth:imex curation|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.06x10^-6(molar)	2021/12/07	2024/11/14	rogid:TxzdCOzqT34oqJsmXiY+Tfr2OJE585396	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	intact-crc:77A9C74D83246032|rigid:InydjguwGJkvNx56sbN43YwFTzs	false	fluorescein isothiocyanate label:n-n|sufficient binding region:471-480|O4'-phospho-L-tyrosine:474-474	sufficient binding region:275-377(IPR035882)	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q83DR9	uniprotkb:Q9ULW5	intact:EBI-44437167	intact:EBI-958239|uniprotkb:Q6NXS7|uniprotkb:Q3L6K5|uniprotkb:B2RAA6|intact:EBI-11079157|ensembl:ENSP00000210187.6	psi-mi:q83dr9_coxbu(display_long)|uniprotkb:CBU_0626(locus name)	psi-mi:rab26_human(display_long)|uniprotkb:RAB26(gene name)|psi-mi:RAB26(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Siadous et al. (2021)	pubmed:32116095|imex:IM-29787	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-44437163|imex:IM-29787-1	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_819656.1|refseq:WP_010957698.1|mint:Q83DR9	"refseq:NP_055168.2|refseq:NP_001294982.1|ensembl:ENSG00000167964.13(gene)|ensembl:ENST00000210187.11(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0019002""(GMP binding)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0035272""(exocrine system development)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0140251""(regulation protein catabolic process at presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:Q9ULW5|rcsb pdb:2G6B|reactome:R-HSA-8873719|panther:PTHR47978(orthology-group)"	-	-	-	figure legend:fig. 5a,c suppl. fig 6b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-u2os)|taxid:9606(Homo sapiens U2OS osteosarcoma cell)	-	2023/05/17	2024/11/14	rogid:a3cfOQBiPrzetDKU+JG6t2tOS3k227377	rogid:kcmXxyYkndHxM/lz+XdGXI1qTzY9606	intact-crc:3B3B61C69D01E857|rigid:jvjbfgqWoD75fsYURo4KLbss3uY	false	ha tag:n-n|mutation with no effect:425-425	green fluorescent protein tag:n-n|mutation with no effect:77-77|mutation decreasing interaction:123-123|mutation increasing interaction:177-177	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9ULW5	uniprotkb:Q83DR9	intact:EBI-958239|uniprotkb:Q6NXS7|uniprotkb:Q3L6K5|uniprotkb:B2RAA6|intact:EBI-11079157|ensembl:ENSP00000210187.6	intact:EBI-44437167	psi-mi:rab26_human(display_long)|uniprotkb:RAB26(gene name)|psi-mi:RAB26(display_short)	psi-mi:q83dr9_coxbu(display_long)|uniprotkb:CBU_0626(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Siadous et al. (2021)	pubmed:32116095|imex:IM-29787	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-44437205|imex:IM-29787-3	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055168.2|refseq:NP_001294982.1|ensembl:ENSG00000167964.13(gene)|ensembl:ENST00000210187.11(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0019002""(GMP binding)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0035272""(exocrine system development)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0140251""(regulation protein catabolic process at presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:Q9ULW5|rcsb pdb:2G6B|reactome:R-HSA-8873719|panther:PTHR47978(orthology-group)"	refseq:NP_819656.1|refseq:WP_010957698.1|mint:Q83DR9	"go:""GO:0005765""(lysosomal membrane)"	-	-	figure legend:fig. 5 b,d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-u2os)|taxid:9606(Homo sapiens U2OS osteosarcoma cell)	-	2023/05/17	2024/11/14	rogid:kcmXxyYkndHxM/lz+XdGXI1qTzY9606	rogid:a3cfOQBiPrzetDKU+JG6t2tOS3k227377	intact-crc:299A6510B4A669CD|rigid:jvjbfgqWoD75fsYURo4KLbss3uY	false	green fluorescent protein tag:n-n|mutation disrupting interaction:123-123|mutation with no effect:177-177|mutation with no effect:77-77	mcherry fluorescent protein tag:n-n|sufficient binding region:370-695	-	-	"psi-mi:""MI:1201""(anti-tag immunocytochemistry)"	"psi-mi:""MI:1201""(anti-tag immunocytochemistry)"
uniprotkb:Q9ULW5	uniprotkb:Q83DR9	intact:EBI-958239|uniprotkb:Q6NXS7|uniprotkb:Q3L6K5|uniprotkb:B2RAA6|intact:EBI-11079157|ensembl:ENSP00000210187.6	intact:EBI-44437167	psi-mi:rab26_human(display_long)|uniprotkb:RAB26(gene name)|psi-mi:RAB26(display_short)	psi-mi:q83dr9_coxbu(display_long)|uniprotkb:CBU_0626(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Siadous et al. (2021)	pubmed:32116095|imex:IM-29787	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:227377(coxbu)|taxid:227377(""Coxiella burnetii (strain RSA 493 / Nine Mile phase I)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-44438732|imex:IM-29787-5	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055168.2|refseq:NP_001294982.1|ensembl:ENSG00000167964.13(gene)|ensembl:ENST00000210187.11(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0017157""(regulation of exocytosis)|go:""GO:0019002""(GMP binding)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0035272""(exocrine system development)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0140251""(regulation protein catabolic process at presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:Q9ULW5|rcsb pdb:2G6B|reactome:R-HSA-8873719|panther:PTHR47978(orthology-group)"	refseq:NP_819656.1|refseq:WP_010957698.1|mint:Q83DR9	"go:""GO:0005765""(lysosomal membrane)"	-	-	figure legend:fig. 8;  suppl. fig.7|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-u2os)|taxid:9606(Homo sapiens U2OS osteosarcoma cell)	-	2023/05/17	2024/11/14	rogid:kcmXxyYkndHxM/lz+XdGXI1qTzY9606	rogid:a3cfOQBiPrzetDKU+JG6t2tOS3k227377	intact-crc:D840495932D87D46|rigid:jvjbfgqWoD75fsYURo4KLbss3uY	false	green fluorescent protein tag:n-n|mutation disrupting interaction:123-123|mutation with no effect:177-177|mutation with no effect:77-77	ha tag:n-n|sufficient binding region:370-695	-	-	"psi-mi:""MI:1201""(anti-tag immunocytochemistry)"	"psi-mi:""MI:1201""(anti-tag immunocytochemistry)"
uniprotkb:Q5ZT54	uniprotkb:Q96QK1	intact:EBI-44436815	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138.7	psi-mi:q5zt54_legph(display_long)|uniprotkb:lpg2311(locus name)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Healy et al. (2023)	pubmed:37172566|imex:IM-29774	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-44436814|imex:IM-29774-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_010948017.1|rcsb pdb:5OSI|rcsb pdb:5OT4|refseq:YP_096320.1	"efo:""Orphanet:411602""|dip:DIP-29076N|rcsb pdb:8R0J|rcsb pdb:8RKS|reactome:R-HSA-3238698|ensembl:ENSG00000069329.19(gene)|ensembl:ENST00000299138.12(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007040""(lysosome organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030906""(retromer, cargo-selective complex)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031648""(protein destabilization)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032463""(negative regulation of protein homooligomerization)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0045056""(transcytosis)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050882""(voluntary musculoskeletal movement)|go:""GO:0051246""(regulation of protein metabolic process)|go:""GO:0060161""(positive regulation of dopamine receptor signaling pathway)|go:""GO:0061357""(positive regulation of Wnt protein secretion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090141""(positive regulation of mitochondrial fission)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090326""(positive regulation of locomotion involved in locomotory behavior)|go:""GO:0097422""(tubular endosome)|go:""GO:0098691""(dopaminergic synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099003""(vesicle-mediated transport in synapse)|go:""GO:0099073""(mitochondrion-derived vesicle)|go:""GO:0099074""(mitochondrion to lysosome vesicle-mediated transport)|go:""GO:0099639""(neurotransmitter receptor transport, endosome to plasma membrane)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902823""(negative regulation of late endosome to lysosome transport)|go:""GO:1902950""(regulation of dendritic spine maintenance)|go:""GO:1903181""(positive regulation of dopamine biosynthetic process)|go:""GO:1903828""(negative regulation of protein localization)|go:""GO:1904377""(positive regulation of protein localization to cell periphery)|go:""GO:1905166""(negative regulation of lysosomal protein catabolic process)|go:""GO:1905606""(regulation of presynapse assembly)|go:""GO:2000331""(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q96QK1|rcsb pdb:2R17|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|rcsb pdb:8R02|refseq:NP_060676.2|panther:PTHR11099(orthology-group)"	-	-	-	figure legend:Supp. Fig. 1H|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/05/17	2025/02/28	rogid:xFWw/eyT0hL16OVYj5aIF9+ncXI272624	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:B8EE4F0A01CCF1EB|rigid:+VWiIq16Qjw5wJuNp+rh+LecZxA	false	mcherry fluorescent protein tag:?-?|sufficient binding region:1-200	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q5ZT54	uniprotkb:O75436	intact:EBI-44436815	intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|uniprotkb:B2RDD3|uniprotkb:A8MZ56|ensembl:ENSP00000263559.6|ensembl:ENSP00000362480.1	psi-mi:q5zt54_legph(display_long)|uniprotkb:lpg2311(locus name)	psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Healy et al. (2023)	pubmed:37172566|imex:IM-29774	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-44436814|imex:IM-29774-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_010948017.1|rcsb pdb:5OSI|rcsb pdb:5OT4|refseq:YP_096320.1	"refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N|ensembl:ENSG00000122958.15(gene)|ensembl:ENST00000263559.11(transcript)|ensembl:ENST00000373382.5(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030906""(retromer, cargo-selective complex)|go:""GO:0031982""(vesicle)|go:""GO:0032456""(endocytic recycling)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0097422""(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:7BLO|reactome:R-HSA-3238698|panther:PTHR12233(orthology-group)"	-	-	-	figure legend:Supp. Fig. 1H|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/05/17	2025/02/28	rogid:xFWw/eyT0hL16OVYj5aIF9+ncXI272624	rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606	intact-crc:B8EE4F0A01CCF1EB|rigid:+VWiIq16Qjw5wJuNp+rh+LecZxA	false	mcherry fluorescent protein tag:?-?|sufficient binding region:1-200	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q5ZT54	uniprotkb:Q9UBQ0	intact:EBI-44436815	intact:EBI-718596|uniprotkb:Q502Y5|uniprotkb:Q9H0W0|uniprotkb:Q9NRP1|uniprotkb:Q6FIF8|uniprotkb:Q6IAH3|uniprotkb:Q9NRU7|ensembl:ENSP00000447058.1	psi-mi:q5zt54_legph(display_long)|uniprotkb:lpg2311(locus name)	psi-mi:vps29_human(display_long)|uniprotkb:Vesicle protein sorting 29(gene name synonym)|uniprotkb:PEP11 homolog(gene name synonym)|uniprotkb:VPS29(gene name)|psi-mi:VPS29(display_short)|uniprotkb:DC7(orf name)|uniprotkb:DC15(orf name)|uniprotkb:MDS007(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Healy et al. (2023)	pubmed:37172566|imex:IM-29774	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-44436814|imex:IM-29774-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_010948017.1|rcsb pdb:5OSI|rcsb pdb:5OT4|refseq:YP_096320.1	"refseq:NP_057310.1|refseq:NP_476528.1|ensembl:ENSG00000111237.19(gene)|ensembl:ENST00000549578.6(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0030904""(retromer complex)|go:""GO:0030906""(retromer, cargo-selective complex)|go:""GO:0032456""(endocytic recycling)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|interpro:IPR000979(Protein of unknown function UPF0025)|interpro:IPR024654|interpro:IPR028661|interpro:IPR029052|mint:Q9UBQ0|rcsb pdb:1W24|rcsb pdb:2R17|rcsb pdb:5GTU|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:5WYH|rcsb pdb:6XS5|rcsb pdb:6XS7|rcsb pdb:6XS9|rcsb pdb:6XSA|rcsb pdb:7BLN|rcsb pdb:8ESE|rcsb pdb:8P0V|rcsb pdb:8P0X|rcsb pdb:8R02|rcsb pdb:8R0J|rcsb pdb:8RKS|rcsb pdb:8SYM|rcsb pdb:8SYN|rcsb pdb:8SYO|reactome:R-HSA-3238698|dip:DIP-29077N|panther:PTHR11124(orthology-group)"	-	-	-	figure legend:Supp. Fig. 1H|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2023/05/17	2025/02/28	rogid:xFWw/eyT0hL16OVYj5aIF9+ncXI272624	rogid:xjo28jAH7expkdli0DENjzLXpjw9606	intact-crc:B8EE4F0A01CCF1EB|rigid:+VWiIq16Qjw5wJuNp+rh+LecZxA	false	mcherry fluorescent protein tag:?-?|sufficient binding region:1-200	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9H0U4	uniprotkb:Q5ZSM7	intact:EBI-1045214|uniprotkb:A8K7S1|ensembl:ENSP00000310226.6	intact:EBI-6666756	psi-mi:rab1b_human(display_long)|uniprotkb:RAB1B(gene name)|psi-mi:RAB1B(display_short)	psi-mi:q5zsm7_legph(display_long)|uniprotkb:lepB(gene name)|psi-mi:lepB(display_short)|uniprotkb:lpg2490(locus name)	"psi-mi:""MI:0114""(x-ray crystallography)"	Mihai et al. (2013)	pubmed:23288104|imex:IM-20541	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-6666777|wwpdb:4I1O|imex:IM-20541-2	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_112243.1|dip:DIP-42462N|ensembl:ENSG00000174903.16(gene)|ensembl:ENST00000311481.11(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0019068""(virion assembly)|go:""GO:0030133""(transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:Q9H0U4|rcsb pdb:3JZA|rcsb pdb:3NKV|rcsb pdb:4HLQ|rcsb pdb:4I1O|rcsb pdb:5O74|rcsb pdb:5SZH|rcsb pdb:5SZK|rcsb pdb:6SKU|rcsb pdb:8ALK|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	"refseq:YP_096497.1|refseq:WP_010948192.1|interpro:IPR040484|interpro:IPR040519|interpro:IPR041585|go:""GO:0016020""(membrane)|rcsb pdb:4I1M|rcsb pdb:4I1O|rcsb pdb:4IRU|mint:Q5ZSM7"	-	-	-	"figure legend:table 1 fig 2 fig 4|3d-resolution:2.7A|3d-r-factors:""\""R-Value: 0.219 R-Free: 0.249\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/09	2025/03/10	rogid:EI6DHq7xCboSkoqGY5NmVY4Iqf09606	rogid:9Eok8GTspDcE6F+y9iArZYGArc8272624	intact-crc:3B0B750172E54FA0|rigid:TWGFfOs1VGrJB/2y8qBLqr7UtE8	false	binding-associated region:3-174	binding-associated region:317-618	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UM99	uniprotkb:P29350	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-78260|intact:EBI-28977917|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67|ensembl:ENSP00000326010.9	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Yan et al. (2012)	pubmed:23001144|imex:IM-20917	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0974""(InnateDB)"	intact:EBI-6674865|imex:IM-20917-1	intact-miscore:0.57	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"panther:PTHR46257(orthology-group)|dip:DIP-31002N|interpro:IPR036860|efo:""Orphanet:3243""|efo:""Orphanet:538863""|efo:""Orphanet:538866""|efo:""Orphanet:538869""|efo:""Orphanet:538872""|ensembl:ENSG00000111679.17(gene)|ensembl:ENST00000318974.14(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002924""(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033007""(negative regulation of mast cell activation involved in immune response)|go:""GO:0033630""(positive regulation of cell adhesion mediated by integrin)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042105""(alpha-beta T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050732""(negative regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905867""(epididymis development)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR052123|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:3PS5|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|rcsb pdb:8YHI|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-201556|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9705671|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|refseq:XP_011519290.1"	-	-	-	figure legend:Fig. 1A, 1C, 1G, 2B|agonist:interaction requires pervanadate|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2013/05/16	2025/03/31	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	intact-crc:21AB687B03F639ED|rigid:aGuqMsA5V3opR84ZFK8vvKok7mo	false	mutation decreasing interaction:483-483|mutation decreasing interaction:511-511|necessary binding region:336-550|mutation decreasing interaction:483-483,511-511|flag tag:?-?	mutation decreasing interaction:453-453|ha tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:B7UM99	uniprotkb:P29350	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-78260|intact:EBI-28977917|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67|ensembl:ENSP00000326010.9	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Yan et al. (2012)	pubmed:23001144|imex:IM-20917	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0974""(InnateDB)"	intact:EBI-6674885|imex:IM-20917-2	intact-miscore:0.57	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"panther:PTHR46257(orthology-group)|dip:DIP-31002N|interpro:IPR036860|efo:""Orphanet:3243""|efo:""Orphanet:538863""|efo:""Orphanet:538866""|efo:""Orphanet:538869""|efo:""Orphanet:538872""|ensembl:ENSG00000111679.17(gene)|ensembl:ENST00000318974.14(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002924""(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033007""(negative regulation of mast cell activation involved in immune response)|go:""GO:0033630""(positive regulation of cell adhesion mediated by integrin)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042105""(alpha-beta T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050732""(negative regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905867""(epididymis development)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR052123|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:3PS5|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|rcsb pdb:8YHI|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-201556|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9705671|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|refseq:XP_011519290.1"	-	-	-	figure legend:Fig. 1B|agonist:pervanadate|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2013/05/16	2025/03/31	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	intact-crc:39A17CAC800183D2|rigid:aGuqMsA5V3opR84ZFK8vvKok7mo	false	flag tag:?-?	ha tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P29350	uniprotkb:Q7DB77	intact:EBI-78260|intact:EBI-28977917|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67|ensembl:ENSP00000326010.9	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Yan et al. (2012)	pubmed:23001144|imex:IM-20917	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0974""(InnateDB)"	intact:EBI-6676123|imex:IM-20917-3	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR46257(orthology-group)|dip:DIP-31002N|interpro:IPR036860|efo:""Orphanet:3243""|efo:""Orphanet:538863""|efo:""Orphanet:538866""|efo:""Orphanet:538869""|efo:""Orphanet:538872""|ensembl:ENSG00000111679.17(gene)|ensembl:ENST00000318974.14(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002924""(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033007""(negative regulation of mast cell activation involved in immune response)|go:""GO:0033630""(positive regulation of cell adhesion mediated by integrin)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042105""(alpha-beta T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050732""(negative regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905867""(epididymis development)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR052123|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:3PS5|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|rcsb pdb:8YHI|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-201556|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9705671|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|refseq:XP_011519290.1"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Fig. S1A.|agonist:pervanadate|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2013/05/16	2025/03/31	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:1382F7CE9ED1BE83|rigid:wACs1MJwo3AnkOKygqOyPHIpvG0	false	ha tag:?-?	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:B7UM99	uniprotkb:P29350	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-78260|intact:EBI-28977917|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67|ensembl:ENSP00000326010.9	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Yan et al. (2012)	pubmed:23001144|imex:IM-20917	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0974""(InnateDB)"	intact:EBI-6676164|imex:IM-20917-5	intact-miscore:0.57	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"panther:PTHR46257(orthology-group)|dip:DIP-31002N|interpro:IPR036860|efo:""Orphanet:3243""|efo:""Orphanet:538863""|efo:""Orphanet:538866""|efo:""Orphanet:538869""|efo:""Orphanet:538872""|ensembl:ENSG00000111679.17(gene)|ensembl:ENST00000318974.14(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002924""(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033007""(negative regulation of mast cell activation involved in immune response)|go:""GO:0033630""(positive regulation of cell adhesion mediated by integrin)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042105""(alpha-beta T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050732""(negative regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905867""(epididymis development)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR052123|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:3PS5|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|rcsb pdb:8YHI|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-201556|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9705671|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|refseq:XP_011519290.1"	"go:""GO:0005829""(cytosol)"	-	-	figure legend:Fig. 1E.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2013/05/16	2025/03/31	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	intact-crc:AF9F2FA38E03D22D|rigid:aGuqMsA5V3opR84ZFK8vvKok7mo	false	ha tag:?-?	flag tag:?-?	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P29350	uniprotkb:B7UM99	intact:EBI-78260|intact:EBI-28977917|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67|ensembl:ENSP00000326010.9	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0096""(pull down)"	Yan et al. (2012)	pubmed:23001144|imex:IM-20917	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0974""(InnateDB)"	intact:EBI-6676182|imex:IM-20917-6	intact-miscore:0.57	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR46257(orthology-group)|dip:DIP-31002N|interpro:IPR036860|efo:""Orphanet:3243""|efo:""Orphanet:538863""|efo:""Orphanet:538866""|efo:""Orphanet:538869""|efo:""Orphanet:538872""|ensembl:ENSG00000111679.17(gene)|ensembl:ENST00000318974.14(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002924""(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033007""(negative regulation of mast cell activation involved in immune response)|go:""GO:0033630""(positive regulation of cell adhesion mediated by integrin)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042105""(alpha-beta T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050732""(negative regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905867""(epididymis development)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR052123|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:3PS5|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|rcsb pdb:8YHI|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-201556|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9705671|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|refseq:XP_011519290.1"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	-	-	-	figure legend:Fig. 2E.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/16	2025/03/31	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:C1BEC2007E089D2C|rigid:aGuqMsA5V3opR84ZFK8vvKok7mo	false	his tag:?-?	phosphorylated residue:511-511|mutation decreasing interaction:483-483,511-511|phosphorylated residue:483-483,511-511|phosphorylated residue:483-483|glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P29350	uniprotkb:Q7DB77	intact:EBI-78260|intact:EBI-28977917|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67|ensembl:ENSP00000326010.9	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Yan et al. (2012)	pubmed:23001144|imex:IM-20917	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0974""(InnateDB)"	intact:EBI-6890968|imex:IM-20917-9	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR46257(orthology-group)|dip:DIP-31002N|interpro:IPR036860|efo:""Orphanet:3243""|efo:""Orphanet:538863""|efo:""Orphanet:538866""|efo:""Orphanet:538869""|efo:""Orphanet:538872""|ensembl:ENSG00000111679.17(gene)|ensembl:ENST00000318974.14(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002924""(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033007""(negative regulation of mast cell activation involved in immune response)|go:""GO:0033630""(positive regulation of cell adhesion mediated by integrin)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042105""(alpha-beta T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050732""(negative regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905867""(epididymis development)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR052123|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:3PS5|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|rcsb pdb:8YHI|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-201556|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9705671|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|refseq:XP_011519290.1"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Fig. S2B.|agonist:pervanadate|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2013/05/16	2025/03/31	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:8B58854FCB970AD2|rigid:wACs1MJwo3AnkOKygqOyPHIpvG0	false	ha tag:?-?	mutation decreasing interaction:490-490,519-519|flag tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q13153	uniprotkb:A0A0H3NGI8	intact:EBI-1307|uniprotkb:O75561|uniprotkb:Q13567|uniprotkb:Q32M53|uniprotkb:Q32M54|uniprotkb:Q86W79|intact:EBI-28976107|ensembl:ENSP00000348696.4	intact:EBI-10686676	psi-mi:pak1_human(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)|uniprotkb:Alpha-PAK(gene name synonym)	psi-mi:a0a0h3ngi8_salts(display_long)|uniprotkb:sopE(gene name)|psi-mi:sopE(display_short)|uniprotkb:SL1344_2674(locus name)	"psi-mi:""MI:0096""(pull down)"	Lim et al. (2014)	imex:IM-25801|pubmed:24625804	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10689573|imex:IM-25801-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122092.1|refseq:NP_002567.3|refseq:XP_011543382.1|refseq:XP_011543383.1|refseq:XP_011543384.1|refseq:XP_011543385.1|refseq:XP_011543386.1|refseq:XP_016873335.1|refseq:XP_016873336.1|refseq:XP_016873337.1|refseq:XP_016873338.1|refseq:XP_016873339.1|dip:DIP-31016N|panther:PTHR48015(orthology-group)|ensembl:ENSG00000149269.10(gene)|ensembl:ENST00000356341.8(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006887""(exocytosis)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0014704""(intercalated disc)|go:""GO:0016310""(phosphorylation)|go:""GO:0016477""(cell migration)|go:""GO:0030018""(Z disc)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033148""(positive regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0050770""(regulation of axonogenesis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0060244""(negative regulation of cell proliferation involved in contact inhibition)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|interpro:IPR051931|mint:Q13153|rcsb pdb:1F3M|rcsb pdb:1YHV|rcsb pdb:1YHW|rcsb pdb:1ZSG|rcsb pdb:2HY8|rcsb pdb:2QME|rcsb pdb:3DVP|rcsb pdb:3FXZ|rcsb pdb:3FY0|rcsb pdb:3Q4Z|rcsb pdb:3Q52|rcsb pdb:3Q53|rcsb pdb:4DAW|rcsb pdb:4EQC|rcsb pdb:4O0R|rcsb pdb:4O0T|rcsb pdb:4P90|rcsb pdb:4ZJI|rcsb pdb:4ZJJ|rcsb pdb:4ZLO|rcsb pdb:4ZY4|rcsb pdb:4ZY5|rcsb pdb:4ZY6|rcsb pdb:5DEW|rcsb pdb:5DEY|rcsb pdb:5DFP|rcsb pdb:5IME|rcsb pdb:5KBQ|rcsb pdb:5KBR|rcsb pdb:6B16|rcsb pdb:7VTO|rcsb pdb:8X5Z|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-445144|reactome:R-HSA-445355|reactome:R-HSA-5218920|reactome:R-HSA-5621575|reactome:R-HSA-5625740|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424"	"uniprotkb:E1WJI8(uniprot-removed-ac)|refseq:WP_000161707.1|interpro:IPR005414(Salmonella type III secretion SopE effector protein)|interpro:IPR016018(Salmonella type III secretion SopE effector protein, N-terminal)|interpro:IPR016019(Salmonella type III secretion SopE effector protein, GEF domain)|interpro:IPR035949|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0030036""(actin cytoskeleton organization)"	-	-	-	figure legend:4C and 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hdf)|taxid:9606(Homo sapiens diploid fibroblasts cells)	-	2015/02/28	2025/02/28	rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606	rogid:jMZa07tHdR7SmHb8YlAPYdvMMCM216597	intact-crc:2C36BBED72AF427C|rigid:vKR0D7KEjZgmpNUyu/odteXKhbM	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q03135	uniprotkb:A0A0H3NGI8	intact:EBI-603614|uniprotkb:Q9UGP1|uniprotkb:Q9UNG1|uniprotkb:Q9UQH6|ensembl:ENSP00000339191.2	intact:EBI-10686676	psi-mi:cav1_human(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)	psi-mi:a0a0h3ngi8_salts(display_long)|uniprotkb:sopE(gene name)|psi-mi:sopE(display_short)|uniprotkb:SL1344_2674(locus name)	"psi-mi:""MI:0096""(pull down)"	Lim et al. (2014)	imex:IM-25801|pubmed:24625804	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10689588|imex:IM-25801-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105974.13(gene)|ensembl:ENST00000341049.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001525""(angiogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0001960""(negative regulation of cytokine-mediated signaling pathway)|go:""GO:0002067""(glandular epithelial cell differentiation)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0002095""(caveolar macromolecular signaling complex)|go:""GO:0002931""(response to ischemia)|go:""GO:0003057""(regulation of the force of heart contraction by chemical signal)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005113""(patched binding)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0005938""(cell cortex)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006940""(regulation of smooth muscle contraction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007595""(lactation)|go:""GO:0008104""(protein localization)|go:""GO:0008142""(oxysterol binding)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009617""(response to bacterium)|go:""GO:0010524""(positive regulation of calcium ion transport into cytosol)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0015031""(protein transport)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0016050""(vesicle organization)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0019065""(receptor-mediated endocytosis of virus by host cell)|go:""GO:0019217""(regulation of fatty acid metabolic process)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019915""(lipid storage)|go:""GO:0030154""(cell differentiation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030857""(negative regulation of epithelial cell differentiation)|go:""GO:0030879""(mammary gland development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032507""(maintenance of protein location in cell)|go:""GO:0032570""(response to progesterone)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033484""(intracellular nitric oxide homeostasis)|go:""GO:0034141""(positive regulation of toll-like receptor 3 signaling pathway)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038166""(angiotensin-activated signaling pathway)|go:""GO:0042310""(vasoconstriction)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043627""(response to estrogen)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044860""(protein localization to plasma membrane raft)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045019""(negative regulation of nitric oxide biosynthetic process)|go:""GO:0045121""(membrane raft)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048550""(negative regulation of pinocytosis)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051899""(membrane depolarization)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060355""(positive regulation of cell adhesion molecule production)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070320""(inward rectifier potassium channel inhibitor activity)|go:""GO:0070836""(caveola assembly)|go:""GO:0071218""(cellular response to misfolded protein)|go:""GO:0071360""(cellular response to exogenous dsRNA)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0071455""(cellular response to hyperoxia)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0098903""(regulation of membrane repolarization during action potential)|go:""GO:0098909""(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900027""(regulation of ruffle assembly)|go:""GO:1901380""(negative regulation of potassium ion transmembrane transport)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1903598""(positive regulation of gap junction assembly)|go:""GO:1903609""(negative regulation of inward rectifier potassium channel activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000535""(regulation of entry of bacterium into host cell)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR018361|mint:Q03135|rcsb pdb:7SC0|reactome:R-HSA-163560|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-210991|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9617828|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001744.2|dip:DIP-5960N|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:275777""|efo:""Orphanet:528""|panther:PTHR10844(orthology-group)"	"uniprotkb:E1WJI8(uniprot-removed-ac)|refseq:WP_000161707.1|interpro:IPR005414(Salmonella type III secretion SopE effector protein)|interpro:IPR016018(Salmonella type III secretion SopE effector protein, N-terminal)|interpro:IPR016019(Salmonella type III secretion SopE effector protein, GEF domain)|interpro:IPR035949|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0030036""(actin cytoskeleton organization)"	-	-	-	figure legend:4C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hdf)|taxid:9606(Homo sapiens diploid fibroblasts cells)	-	2015/02/28	2025/02/28	rogid:+JhGp5YmhT3JLeTgHHBTHu9r34c9606	rogid:jMZa07tHdR7SmHb8YlAPYdvMMCM216597	intact-crc:2C5D2B4274C206E5|rigid:+Nuy726NM7CsK2qIGJCPVZpD5y8	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q13153	uniprotkb:A0A0H3NGI8	intact:EBI-1307|uniprotkb:O75561|uniprotkb:Q13567|uniprotkb:Q32M53|uniprotkb:Q32M54|uniprotkb:Q86W79|intact:EBI-28976107|ensembl:ENSP00000348696.4	intact:EBI-10686676	psi-mi:pak1_human(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)|uniprotkb:Alpha-PAK(gene name synonym)	psi-mi:a0a0h3ngi8_salts(display_long)|uniprotkb:sopE(gene name)|psi-mi:sopE(display_short)|uniprotkb:SL1344_2674(locus name)	"psi-mi:""MI:0096""(pull down)"	Lim et al. (2014)	imex:IM-25801|pubmed:24625804	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10689603|imex:IM-25801-9	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122092.1|refseq:NP_002567.3|refseq:XP_011543382.1|refseq:XP_011543383.1|refseq:XP_011543384.1|refseq:XP_011543385.1|refseq:XP_011543386.1|refseq:XP_016873335.1|refseq:XP_016873336.1|refseq:XP_016873337.1|refseq:XP_016873338.1|refseq:XP_016873339.1|dip:DIP-31016N|panther:PTHR48015(orthology-group)|ensembl:ENSG00000149269.10(gene)|ensembl:ENST00000356341.8(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006887""(exocytosis)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0014704""(intercalated disc)|go:""GO:0016310""(phosphorylation)|go:""GO:0016477""(cell migration)|go:""GO:0030018""(Z disc)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033148""(positive regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0050770""(regulation of axonogenesis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0060244""(negative regulation of cell proliferation involved in contact inhibition)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|interpro:IPR051931|mint:Q13153|rcsb pdb:1F3M|rcsb pdb:1YHV|rcsb pdb:1YHW|rcsb pdb:1ZSG|rcsb pdb:2HY8|rcsb pdb:2QME|rcsb pdb:3DVP|rcsb pdb:3FXZ|rcsb pdb:3FY0|rcsb pdb:3Q4Z|rcsb pdb:3Q52|rcsb pdb:3Q53|rcsb pdb:4DAW|rcsb pdb:4EQC|rcsb pdb:4O0R|rcsb pdb:4O0T|rcsb pdb:4P90|rcsb pdb:4ZJI|rcsb pdb:4ZJJ|rcsb pdb:4ZLO|rcsb pdb:4ZY4|rcsb pdb:4ZY5|rcsb pdb:4ZY6|rcsb pdb:5DEW|rcsb pdb:5DEY|rcsb pdb:5DFP|rcsb pdb:5IME|rcsb pdb:5KBQ|rcsb pdb:5KBR|rcsb pdb:6B16|rcsb pdb:7VTO|rcsb pdb:8X5Z|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-445144|reactome:R-HSA-445355|reactome:R-HSA-5218920|reactome:R-HSA-5621575|reactome:R-HSA-5625740|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424"	"uniprotkb:E1WJI8(uniprot-removed-ac)|refseq:WP_000161707.1|interpro:IPR005414(Salmonella type III secretion SopE effector protein)|interpro:IPR016018(Salmonella type III secretion SopE effector protein, N-terminal)|interpro:IPR016019(Salmonella type III secretion SopE effector protein, GEF domain)|interpro:IPR035949|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0030036""(actin cytoskeleton organization)"	-	-	-	figure legend:suppl. data 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hdf)|taxid:9606(Homo sapiens diploid fibroblasts cells)	-	2015/02/28	2025/02/28	rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606	rogid:jMZa07tHdR7SmHb8YlAPYdvMMCM216597	intact-crc:0BBA01E27C80933E|rigid:vKR0D7KEjZgmpNUyu/odteXKhbM	false	-	ha tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NGI8	uniprotkb:Q03135	intact:EBI-10686676	intact:EBI-603614|uniprotkb:Q9UGP1|uniprotkb:Q9UNG1|uniprotkb:Q9UQH6|ensembl:ENSP00000339191.2	psi-mi:a0a0h3ngi8_salts(display_long)|uniprotkb:sopE(gene name)|psi-mi:sopE(display_short)|uniprotkb:SL1344_2674(locus name)	psi-mi:cav1_human(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Lim et al. (2014)	imex:IM-25801|pubmed:24625804	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10689612|imex:IM-25801-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WJI8(uniprot-removed-ac)|refseq:WP_000161707.1|interpro:IPR005414(Salmonella type III secretion SopE effector protein)|interpro:IPR016018(Salmonella type III secretion SopE effector protein, N-terminal)|interpro:IPR016019(Salmonella type III secretion SopE effector protein, GEF domain)|interpro:IPR035949|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0030036""(actin cytoskeleton organization)"	"ensembl:ENSG00000105974.13(gene)|ensembl:ENST00000341049.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001525""(angiogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0001960""(negative regulation of cytokine-mediated signaling pathway)|go:""GO:0002067""(glandular epithelial cell differentiation)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0002095""(caveolar macromolecular signaling complex)|go:""GO:0002931""(response to ischemia)|go:""GO:0003057""(regulation of the force of heart contraction by chemical signal)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005113""(patched binding)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0005938""(cell cortex)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006940""(regulation of smooth muscle contraction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007595""(lactation)|go:""GO:0008104""(protein localization)|go:""GO:0008142""(oxysterol binding)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009617""(response to bacterium)|go:""GO:0010524""(positive regulation of calcium ion transport into cytosol)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0015031""(protein transport)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0016050""(vesicle organization)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0019065""(receptor-mediated endocytosis of virus by host cell)|go:""GO:0019217""(regulation of fatty acid metabolic process)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019915""(lipid storage)|go:""GO:0030154""(cell differentiation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030857""(negative regulation of epithelial cell differentiation)|go:""GO:0030879""(mammary gland development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032507""(maintenance of protein location in cell)|go:""GO:0032570""(response to progesterone)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033484""(intracellular nitric oxide homeostasis)|go:""GO:0034141""(positive regulation of toll-like receptor 3 signaling pathway)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038166""(angiotensin-activated signaling pathway)|go:""GO:0042310""(vasoconstriction)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043627""(response to estrogen)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044860""(protein localization to plasma membrane raft)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045019""(negative regulation of nitric oxide biosynthetic process)|go:""GO:0045121""(membrane raft)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048550""(negative regulation of pinocytosis)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051899""(membrane depolarization)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060355""(positive regulation of cell adhesion molecule production)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070320""(inward rectifier potassium channel inhibitor activity)|go:""GO:0070836""(caveola assembly)|go:""GO:0071218""(cellular response to misfolded protein)|go:""GO:0071360""(cellular response to exogenous dsRNA)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0071455""(cellular response to hyperoxia)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0098903""(regulation of membrane repolarization during action potential)|go:""GO:0098909""(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900027""(regulation of ruffle assembly)|go:""GO:1901380""(negative regulation of potassium ion transmembrane transport)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1903598""(positive regulation of gap junction assembly)|go:""GO:1903609""(negative regulation of inward rectifier potassium channel activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000535""(regulation of entry of bacterium into host cell)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR018361|mint:Q03135|rcsb pdb:7SC0|reactome:R-HSA-163560|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-210991|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9617828|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001744.2|dip:DIP-5960N|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:275777""|efo:""Orphanet:528""|panther:PTHR10844(orthology-group)"	-	-	-	figure legend:suppl. data 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hdf)|taxid:9606(Homo sapiens diploid fibroblasts cells)	-	2015/02/28	2025/02/28	rogid:jMZa07tHdR7SmHb8YlAPYdvMMCM216597	rogid:+JhGp5YmhT3JLeTgHHBTHu9r34c9606	intact-crc:8D35ECF784FA7BBA|rigid:+Nuy726NM7CsK2qIGJCPVZpD5y8	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NGI8	uniprotkb:P63000	intact:EBI-10686676	intact:EBI-413628|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q9BTB4|uniprotkb:Q5JAA8|ensembl:ENSP00000258737.7	psi-mi:a0a0h3ngi8_salts(display_long)|uniprotkb:sopE(gene name)|psi-mi:sopE(display_short)|uniprotkb:SL1344_2674(locus name)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Lim et al. (2014)	imex:IM-25801|pubmed:24625804	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10689612|imex:IM-25801-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WJI8(uniprot-removed-ac)|refseq:WP_000161707.1|interpro:IPR005414(Salmonella type III secretion SopE effector protein)|interpro:IPR016018(Salmonella type III secretion SopE effector protein, N-terminal)|interpro:IPR016019(Salmonella type III secretion SopE effector protein, GEF domain)|interpro:IPR035949|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0030036""(actin cytoskeleton organization)"	"efo:""Orphanet:500159""|ensembl:ENSG00000136238.20(gene)|ensembl:ENST00000348035.9(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006954""(inflammatory response)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009611""(response to wounding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031529""(ruffle organization)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032707""(negative regulation of interleukin-23 production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042470""(melanosome)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045428""(regulation of nitric oxide biosynthetic process)|go:""GO:0045730""(respiratory burst)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048870""(cell motility)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051668""(localization within membrane)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060263""(regulation of respiratory burst)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0097178""(ruffle assembly)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902622""(regulation of neutrophil migration)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:7DPA|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|rcsb pdb:7SJ4|rcsb pdb:7USD|rcsb pdb:7USE|rcsb pdb:8I5V|rcsb pdb:8I5W|rcsb pdb:8Q0N|rcsb pdb:8WEJ|rcsb pdb:8ZJ2|rcsb pdb:8ZJI|rcsb pdb:8ZJJ|rcsb pdb:8ZJK|rcsb pdb:8ZJL|rcsb pdb:8ZJM|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-9748787|reactome:R-HSA-983231|refseq:NP_008839.2|refseq:NP_061485.1|dip:DIP-29260N|panther:PTHR24072(orthology-group)|ensembl:ENSP00000258737.7|ensembl:ENST00000356142.4|ensembl:ENSP00000348461.4"	-	-	-	figure legend:suppl. data 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hdf)|taxid:9606(Homo sapiens diploid fibroblasts cells)	-	2015/02/28	2025/02/28	rogid:jMZa07tHdR7SmHb8YlAPYdvMMCM216597	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:8D35ECF784FA7BBA|rigid:+Nuy726NM7CsK2qIGJCPVZpD5y8	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y2Z0	intact:EBI-10689860	intact:EBI-307008|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6|ensembl:ENSP00000367208.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Bhavsar et al. (2012)	pubmed:23935490|imex:IM-26065	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10689858|imex:IM-26065-1	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"refseq:NP_001124384.1|refseq:NP_006695.1|ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000343788.10(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007051""(spindle organization)|go:""GO:0014841""(skeletal muscle satellite cell proliferation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032991""(protein-containing complex)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0106222""(lncRNA binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|reactome:R-HSA-9660826|refseq:NP_001307760.1|dip:DIP-53799N|panther:PTHR45862(orthology-group)"	-	-	-	figure legend:1A, 1E and suppl fig 1A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/11	2025/02/27	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	intact-crc:40F53A42D21508F8|rigid:4rkY4BDd6G7qOY5GxqK9Y4odu4A	false	sufficient binding region:171-479|necessary binding region:430-479|ha tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y239	intact:EBI-10689860	intact:EBI-1051262|uniprotkb:Q549U4|uniprotkb:Q8IWF5|uniprotkb:B4DTU3|ensembl:ENSP00000222823.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:nod1_human(display_long)|uniprotkb:Caspase recruitment domain-containing protein 4(gene name synonym)|uniprotkb:NOD1(gene name)|psi-mi:NOD1(display_short)|uniprotkb:CARD4(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Bhavsar et al. (2012)	pubmed:23935490|imex:IM-26065	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10766573|imex:IM-26065-25	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"refseq:NP_006083.1|refseq:XP_011513386.1|refseq:XP_016867164.1|refseq:XP_005249625.1|refseq:XP_005249629.1|refseq:XP_006715696.1|refseq:XP_011513381.1|refseq:XP_011513382.1|refseq:XP_011513383.1|dip:DIP-41064N|ensembl:ENSG00000106100.11(gene)|ensembl:ENST00000222823.9(transcript)|go:""GO:0002221""(pattern recognition receptor signaling pathway)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0009595""(detection of biotic stimulus)|go:""GO:0016045""(detection of bacterium)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032874""(positive regulation of stress-activated MAPK cascade)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042834""(peptidoglycan binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0050700""(CARD domain binding)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070427""(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:""GO:0071225""(cellular response to muramyl dipeptide)|go:""GO:0098792""(xenophagy)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904417""(positive regulation of xenophagy)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|interpro:IPR051261|mint:Q9Y239|rcsb pdb:2B1W|rcsb pdb:2DBD|rcsb pdb:2NSN|rcsb pdb:2NZ7|rcsb pdb:4E9M|rcsb pdb:4JQW|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-9705671|panther:PTHR24106(orthology-group)"	-	-	-	figure legend:6B|comment:A putative ternary complex between SspH2, Nod1 and  SGT1 identified|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/11	2025/02/27	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:JGA4XuGCPNqNeESAMbr7aKVgZP89606	intact-crc:2CB2C5BE70446852|rigid:nsvxnS6TJVFeqxErkOgvoLKRXEA	false	ha tag:n-n	flag tag:c-c	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y2Z0	intact:EBI-10689860	intact:EBI-307008|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6|ensembl:ENSP00000367208.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Bhavsar et al. (2012)	pubmed:23935490|imex:IM-26065	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10766573|imex:IM-26065-25	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"refseq:NP_001124384.1|refseq:NP_006695.1|ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000343788.10(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007051""(spindle organization)|go:""GO:0014841""(skeletal muscle satellite cell proliferation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032991""(protein-containing complex)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0106222""(lncRNA binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|reactome:R-HSA-9660826|refseq:NP_001307760.1|dip:DIP-53799N|panther:PTHR45862(orthology-group)"	-	-	-	figure legend:6B|comment:A putative ternary complex between SspH2, Nod1 and  SGT1 identified|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/11	2025/02/27	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	intact-crc:2CB2C5BE70446852|rigid:nsvxnS6TJVFeqxErkOgvoLKRXEA	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q9Y239	uniprotkb:A0A0H3NF38	intact:EBI-1051262|uniprotkb:Q549U4|uniprotkb:Q8IWF5|uniprotkb:B4DTU3|ensembl:ENSP00000222823.4	intact:EBI-10689860	psi-mi:nod1_human(display_long)|uniprotkb:Caspase recruitment domain-containing protein 4(gene name synonym)|uniprotkb:NOD1(gene name)|psi-mi:NOD1(display_short)|uniprotkb:CARD4(gene name synonym)	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Bhavsar et al. (2012)	pubmed:23935490|imex:IM-26065	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10768084|imex:IM-26065-17	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006083.1|refseq:XP_011513386.1|refseq:XP_016867164.1|refseq:XP_005249625.1|refseq:XP_005249629.1|refseq:XP_006715696.1|refseq:XP_011513381.1|refseq:XP_011513382.1|refseq:XP_011513383.1|dip:DIP-41064N|ensembl:ENSG00000106100.11(gene)|ensembl:ENST00000222823.9(transcript)|go:""GO:0002221""(pattern recognition receptor signaling pathway)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0009595""(detection of biotic stimulus)|go:""GO:0016045""(detection of bacterium)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032874""(positive regulation of stress-activated MAPK cascade)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042834""(peptidoglycan binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0050700""(CARD domain binding)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070427""(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:""GO:0071225""(cellular response to muramyl dipeptide)|go:""GO:0098792""(xenophagy)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904417""(positive regulation of xenophagy)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|interpro:IPR051261|mint:Q9Y239|rcsb pdb:2B1W|rcsb pdb:2DBD|rcsb pdb:2NSN|rcsb pdb:2NZ7|rcsb pdb:4E9M|rcsb pdb:4JQW|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-9705671|panther:PTHR24106(orthology-group)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	-	-	-	figure legend:6B|comment:A putative ternary complex between SspH2, Nod1 and  SGT1 identified|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/11	2025/02/27	rogid:JGA4XuGCPNqNeESAMbr7aKVgZP89606	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	intact-crc:43CAEAFAAEBFDE8A|rigid:nsvxnS6TJVFeqxErkOgvoLKRXEA	false	flag tag:c-c	ha tag:n-n	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y2Z0	intact:EBI-10689860	intact:EBI-307008|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6|ensembl:ENSP00000367208.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Bhavsar et al. (2012)	pubmed:23935490|imex:IM-26065	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10689882|imex:IM-26065-3	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"refseq:NP_001124384.1|refseq:NP_006695.1|ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000343788.10(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007051""(spindle organization)|go:""GO:0014841""(skeletal muscle satellite cell proliferation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032991""(protein-containing complex)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0106222""(lncRNA binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|reactome:R-HSA-9660826|refseq:NP_001307760.1|dip:DIP-53799N|panther:PTHR45862(orthology-group)"	-	-	-	figure legend:1B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2015/03/11	2025/02/27	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	intact-crc:5B91B048F1403E98|rigid:4rkY4BDd6G7qOY5GxqK9Y4odu4A	false	flag tag:c-c	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y2Z0-2	intact:EBI-10689860	intact:EBI-10768076|ensembl:ENSP00000308067.7	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:q9y2z0-2(display_long)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)|uniprotkb:SGT1A(isoform synonym)|uniprotkb:SUGT1A(isoform synonym)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Bhavsar et al. (2012)	pubmed:23935490|imex:IM-26065	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10766141|imex:IM-26065-11	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000310528.9(transcript)|intact:EBI-307008(isoform-parent)|uniprotkb:Q9Y2Z0-2(isoform-parent)	-	-	-	figure legend:1E and suppl figure 1B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/11	2024/11/14	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:LGEUHwisWjGnJ41eZHpbz7KfxHQ9606	intact-crc:B3EBC9EEC4EA20C5|rigid:v+sDuQvm0yn7cKswZia+kpy1GZ0	false	ha tag:n-n	flag tag:c-c|necessary binding region:260-333|sufficient binding region:111-333	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y239	intact:EBI-10689860	intact:EBI-1051262|uniprotkb:Q549U4|uniprotkb:Q8IWF5|uniprotkb:B4DTU3|ensembl:ENSP00000222823.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:nod1_human(display_long)|uniprotkb:Caspase recruitment domain-containing protein 4(gene name synonym)|uniprotkb:NOD1(gene name)|psi-mi:NOD1(display_short)|uniprotkb:CARD4(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Bhavsar et al. (2012)	pubmed:23935490|imex:IM-26065	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10766584|imex:IM-26065-13	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"refseq:NP_006083.1|refseq:XP_011513386.1|refseq:XP_016867164.1|refseq:XP_005249625.1|refseq:XP_005249629.1|refseq:XP_006715696.1|refseq:XP_011513381.1|refseq:XP_011513382.1|refseq:XP_011513383.1|dip:DIP-41064N|ensembl:ENSG00000106100.11(gene)|ensembl:ENST00000222823.9(transcript)|go:""GO:0002221""(pattern recognition receptor signaling pathway)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0009595""(detection of biotic stimulus)|go:""GO:0016045""(detection of bacterium)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032874""(positive regulation of stress-activated MAPK cascade)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042834""(peptidoglycan binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0050700""(CARD domain binding)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070427""(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:""GO:0071225""(cellular response to muramyl dipeptide)|go:""GO:0098792""(xenophagy)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904417""(positive regulation of xenophagy)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|interpro:IPR051261|mint:Q9Y239|rcsb pdb:2B1W|rcsb pdb:2DBD|rcsb pdb:2NSN|rcsb pdb:2NZ7|rcsb pdb:4E9M|rcsb pdb:4JQW|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-9705671|panther:PTHR24106(orthology-group)"	-	-	-	figure legend:6A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/11	2024/11/14	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:JGA4XuGCPNqNeESAMbr7aKVgZP89606	intact-crc:6634B1E4B83D1413|rigid:Ze1Dipcjt91uMwa/d1UemZLgG38	false	ha tag:n-n	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y239	intact:EBI-10689860	intact:EBI-1051262|uniprotkb:Q549U4|uniprotkb:Q8IWF5|uniprotkb:B4DTU3|ensembl:ENSP00000222823.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:nod1_human(display_long)|uniprotkb:Caspase recruitment domain-containing protein 4(gene name synonym)|uniprotkb:NOD1(gene name)|psi-mi:NOD1(display_short)|uniprotkb:CARD4(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Bhavsar et al. (2012)	pubmed:23935490|imex:IM-26065	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10766594|imex:IM-26065-15	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"refseq:NP_006083.1|refseq:XP_011513386.1|refseq:XP_016867164.1|refseq:XP_005249625.1|refseq:XP_005249629.1|refseq:XP_006715696.1|refseq:XP_011513381.1|refseq:XP_011513382.1|refseq:XP_011513383.1|dip:DIP-41064N|ensembl:ENSG00000106100.11(gene)|ensembl:ENST00000222823.9(transcript)|go:""GO:0002221""(pattern recognition receptor signaling pathway)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0009595""(detection of biotic stimulus)|go:""GO:0016045""(detection of bacterium)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032874""(positive regulation of stress-activated MAPK cascade)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042834""(peptidoglycan binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0050700""(CARD domain binding)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070427""(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:""GO:0071225""(cellular response to muramyl dipeptide)|go:""GO:0098792""(xenophagy)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904417""(positive regulation of xenophagy)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|interpro:IPR051261|mint:Q9Y239|rcsb pdb:2B1W|rcsb pdb:2DBD|rcsb pdb:2NSN|rcsb pdb:2NZ7|rcsb pdb:4E9M|rcsb pdb:4JQW|reactome:R-HSA-168638|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-9705671|panther:PTHR24106(orthology-group)"	-	-	-	figure legend:6A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/11	2024/11/14	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:JGA4XuGCPNqNeESAMbr7aKVgZP89606	intact-crc:C46F187268E59463|rigid:Ze1Dipcjt91uMwa/d1UemZLgG38	false	ha tag:n-n	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y2Z0-2	intact:EBI-10689860	intact:EBI-10768076|ensembl:ENSP00000308067.7	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:q9y2z0-2(display_long)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)|uniprotkb:SGT1A(isoform synonym)|uniprotkb:SUGT1A(isoform synonym)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Bhavsar et al. (2012)	pubmed:23935490|imex:IM-26065	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10768096|imex:IM-26065-19	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000310528.9(transcript)|intact:EBI-307008(isoform-parent)|uniprotkb:Q9Y2Z0-2(isoform-parent)	-	-	-	figure legend:suppl figure 1B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/11	2024/11/14	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:LGEUHwisWjGnJ41eZHpbz7KfxHQ9606	intact-crc:3C2168CFC3467E44|rigid:v+sDuQvm0yn7cKswZia+kpy1GZ0	false	ha tag:n-n|sufficient binding region:236-528	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y2Z0	intact:EBI-10689860	intact:EBI-307008|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6|ensembl:ENSP00000367208.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Bhavsar et al. (2012)	pubmed:23935490|imex:IM-26065	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10766107|imex:IM-26065-23	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"refseq:NP_001124384.1|refseq:NP_006695.1|ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000343788.10(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007051""(spindle organization)|go:""GO:0014841""(skeletal muscle satellite cell proliferation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032991""(protein-containing complex)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0106222""(lncRNA binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|reactome:R-HSA-9660826|refseq:NP_001307760.1|dip:DIP-53799N|panther:PTHR45862(orthology-group)"	-	-	-	figure legend:1A and suppl fig 1A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/11	2025/02/27	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	intact-crc:B34DB5AD7A285B36|rigid:4rkY4BDd6G7qOY5GxqK9Y4odu4A	false	ha tag:n-n|necessary binding region:430-491	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NA16	uniprotkb:P60953	intact:EBI-10726187	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:a0a0h3na16_salts(display_long)|uniprotkb:G1X32_21660(orf name)|uniprotkb:G1X38_21955(orf name)|uniprotkb:G1X42_20695(orf name)|uniprotkb:G1X47_21385(orf name)|uniprotkb:G1X49_21885(orf name)|uniprotkb:G1X51_21455(orf name)|uniprotkb:G1X52_21395(orf name)|uniprotkb:G1X66_21475(orf name)|uniprotkb:G1X68_18020(orf name)|uniprotkb:G1X69_21975(orf name)|uniprotkb:G1X71_21710(orf name)|uniprotkb:G1X76_21360(orf name)|uniprotkb:G1X80_21495(orf name)|uniprotkb:G1X84_21405(orf name)|uniprotkb:G1X85_20930(orf name)|uniprotkb:G1X86_21700(orf name)|uniprotkb:G1X94_21565(orf name)|uniprotkb:G1X96_21705(orf name)|uniprotkb:G1X99_21920(orf name)|uniprotkb:G1Y02_21400(orf name)|uniprotkb:SL1344_1030(locus name)|uniprotkb:sopB(gene name)|psi-mi:sopB(display_short)|uniprotkb:Effector protein SopB(gene name synonym)|uniprotkb:sigD(gene name synonym)|uniprotkb:G1W50_21240(orf name)|uniprotkb:G1W53_21100(orf name)|uniprotkb:G1W54_21690(orf name)|uniprotkb:G1W56_21065(orf name)|uniprotkb:G1W63_21110(orf name)|uniprotkb:G1W64_21805(orf name)|uniprotkb:G1W86_20115(orf name)|uniprotkb:G1W87_20995(orf name)|uniprotkb:G1W89_20265(orf name)|uniprotkb:G1W92_20690(orf name)|uniprotkb:G1X03_20885(orf name)|uniprotkb:G1X04_08935(orf name)|uniprotkb:G1X09_22275(orf name)|uniprotkb:G1X10_21625(orf name)|uniprotkb:G1X13_21700(orf name)|uniprotkb:G1X17_22505(orf name)|uniprotkb:G1X23_21605(orf name)|uniprotkb:G1X29_21410(orf name)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690134|imex:IM-25980-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1W7C2(uniprot-removed-ac)|refseq:WP_001166946.1|interpro:IPR008108(Type III secretion system outer membrane, B protein)|go:""GO:0005576""(extracellular region)|go:""GO:0016791""(phosphatase activity)"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2024/11/07	rogid:UQwDH+y4MXGRiHj5Fn4PM/N6afI216597	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:3F284069B7E09554|rigid:3+6MfJSgUABTq8JG8/8Icx/cUEY	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NG92	uniprotkb:P14923	intact:EBI-10726177	intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113.5|ensembl:ENSP00000377507.1|ensembl:ENSP00000377508.3	psi-mi:a0a0h3ng92_salts(display_long)|uniprotkb:sseF(gene name)|psi-mi:sseF(display_short)|uniprotkb:G1W50_11000(orf name)|uniprotkb:G1W53_02225(orf name)|uniprotkb:G1W54_02225(orf name)|uniprotkb:G1W56_05580(orf name)|uniprotkb:G1W63_02225(orf name)|uniprotkb:G1W64_07985(orf name)|uniprotkb:G1W86_01905(orf name)|uniprotkb:G1W87_09740(orf name)|uniprotkb:G1W89_05010(orf name)|uniprotkb:G1W92_07445(orf name)|uniprotkb:G1X04_02010(orf name)|uniprotkb:G1X09_05320(orf name)|uniprotkb:G1X10_02225(orf name)|uniprotkb:G1X13_05320(orf name)|uniprotkb:G1X17_05320(orf name)|uniprotkb:G1X23_02210(orf name)|uniprotkb:G1X29_05320(orf name)|uniprotkb:G1X32_04905(orf name)|uniprotkb:G1X38_02225(orf name)|uniprotkb:G1X42_07445(orf name)|uniprotkb:G1X47_04890(orf name)|uniprotkb:G1X49_02225(orf name)|uniprotkb:G1X51_05320(orf name)|uniprotkb:G1X52_07990(orf name)|uniprotkb:G1X66_02225(orf name)|uniprotkb:G1X68_02225(orf name)|uniprotkb:G1X69_05585(orf name)|uniprotkb:G1X71_05325(orf name)|uniprotkb:G1X76_02225(orf name)|uniprotkb:G1X80_02225(orf name)|uniprotkb:G1X84_04910(orf name)|uniprotkb:G1X85_02225(orf name)|uniprotkb:G1X86_07670(orf name)|uniprotkb:G1X94_04890(orf name)|uniprotkb:G1X96_07675(orf name)|uniprotkb:G1X99_08000(orf name)|uniprotkb:G1Y02_04910(orf name)|uniprotkb:SL1344_1338(locus name)	psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690173|imex:IM-25980-3	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS0(uniprot-removed-ac)|refseq:WP_000690718.1|go:""GO:0016020""(membrane)|mint:A0A0H3NG92"	"efo:""Orphanet:158687""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:34217""|ensembl:ENSG00000173801.17(gene)|ensembl:ENST00000310706.9(transcript)|ensembl:ENST00000393930.5(transcript)|ensembl:ENST00000393931.8(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0002159""(desmosome assembly)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0014704""(intercalated disc)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030018""(Z disc)|go:""GO:0030057""(desmosome)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0043588""(skin development)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050982""(detection of mechanical stimulus)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071603""(endothelial cell-cell adhesion)|go:""GO:0071665""(gamma-catenin-TCF7L2 complex)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0086073""(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:""GO:0086083""(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0106006""(cytoskeletal protein-membrane anchor activity)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9833576|refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_016880079.1|dip:DIP-36235N|panther:PTHR45976(orthology-group)"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/03/10	rogid:z/dRlfvd+RvtrXbPxKwY+K4CHHc216597	rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606	intact-crc:A4D595D872875934|rigid:HJEvwvbYcAc3SL90rmsVVDrCmQI	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NB75	uniprotkb:P15924	intact:EBI-10726196	intact:EBI-355041|uniprotkb:O75993|uniprotkb:Q14189|uniprotkb:Q9UHN4|uniprotkb:B2RTT2|ensembl:ENSP00000369129.3|uniprotkb:D7RX09	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:desp_human(display_long)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690185|imex:IM-25980-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000096696.17(gene)|ensembl:ENST00000379802.8(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0002934""(desmosome organization)|go:""GO:0003223""(ventricular compact myocardium morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005916""(fascia adherens)|go:""GO:0008544""(epidermis development)|go:""GO:0014704""(intercalated disc)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0030057""(desmosome)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0034332""(adherens junction organization)|go:""GO:0042060""(wound healing)|go:""GO:0043588""(skin development)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0045109""(intermediate filament organization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0086073""(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:""GO:0086083""(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0150105""(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:P15924|rcsb pdb:1LM5|rcsb pdb:1LM7|rcsb pdb:3R6N|rcsb pdb:5DZZ|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696273|refseq:NP_001008844.1|refseq:NP_001305963.1|refseq:NP_004406.2|efo:""Orphanet:154""|efo:""Orphanet:158687""|efo:""Orphanet:2032""|efo:""Orphanet:293165""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:369992""|efo:""Orphanet:476096""|efo:""Orphanet:50942""|efo:""Orphanet:65282""|dip:DIP-109N|panther:PTHR23169(orthology-group)"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606	intact-crc:8B41DE9E7A65263B|rigid:IjlNBrsS754e1LWXA1RByyOcaLk	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NB75	uniprotkb:Q14444	intact:EBI-10726196	intact:EBI-1047080|uniprotkb:Q15074|intact:EBI-1171814|uniprotkb:Q6IMN4|uniprotkb:A6NMY7|uniprotkb:Q6IMN7|uniprotkb:Q9BV09|intact:EBI-2562858|ensembl:ENSP00000340329.4|ensembl:ENSP00000434150.1|intact:EBI-3449178|uniprotkb:D3DR06	psi-mi:a0a0h3nb75_salts(display_long)|uniprotkb:sseG(gene name)|psi-mi:sseG(display_short)|uniprotkb:G1W50_10995(orf name)|uniprotkb:G1W53_02220(orf name)|uniprotkb:G1W54_02220(orf name)|uniprotkb:G1W56_05575(orf name)|uniprotkb:G1W63_02220(orf name)|uniprotkb:G1W64_07980(orf name)|uniprotkb:G1W86_01900(orf name)|uniprotkb:G1W87_09735(orf name)|uniprotkb:G1W89_05005(orf name)|uniprotkb:G1W92_07440(orf name)|uniprotkb:G1X03_02220(orf name)|uniprotkb:G1X04_02005(orf name)|uniprotkb:G1X09_05315(orf name)|uniprotkb:G1X10_02220(orf name)|uniprotkb:G1X13_05315(orf name)|uniprotkb:G1X17_05315(orf name)|uniprotkb:G1X23_02205(orf name)|uniprotkb:G1X29_05315(orf name)|uniprotkb:G1X32_04900(orf name)|uniprotkb:G1X38_02220(orf name)|uniprotkb:G1X42_07440(orf name)|uniprotkb:G1X47_04885(orf name)|uniprotkb:G1X49_02220(orf name)|uniprotkb:G1X51_05315(orf name)|uniprotkb:G1X52_07985(orf name)|uniprotkb:G1X66_02220(orf name)|uniprotkb:G1X68_02220(orf name)|uniprotkb:G1X69_05580(orf name)|uniprotkb:G1X71_05320(orf name)|uniprotkb:G1X76_02220(orf name)|uniprotkb:G1X80_02220(orf name)|uniprotkb:G1X84_04905(orf name)|uniprotkb:G1X85_02220(orf name)|uniprotkb:G1X86_07665(orf name)|uniprotkb:G1X94_04885(orf name)|uniprotkb:G1X96_07670(orf name)|uniprotkb:G1X99_07995(orf name)|uniprotkb:G1Y02_04905(orf name)|uniprotkb:SL1344_1339(locus name)	psi-mi:capr1_human(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690185|imex:IM-25980-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WFS1(uniprot-removed-ac)|refseq:WP_000805851.1|go:""GO:0016020""(membrane)|mint:A0A0H3NB75"	"ensembl:ENSG00000135387.21(gene)|ensembl:ENST00000341394.9(transcript)|ensembl:ENST00000532820.5(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007416""(synapse assembly)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030425""(dendrite)|go:""GO:0031252""(cell leading edge)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0045202""(synapse)|go:""GO:0048699""(generation of neurons)|go:""GO:0050775""(positive regulation of dendrite morphogenesis)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0106288""(regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|interpro:IPR022070|interpro:IPR028816|interpro:IPR041637|mint:Q14444|rcsb pdb:4WBE|rcsb pdb:4WBP|rcsb pdb:6TA7|rcsb pdb:7XHG|rcsb pdb:8TH7|refseq:NP_005889.3|refseq:NP_976240.1|refseq:XP_016873238.1|efo:""Orphanet:528084""|panther:PTHR22922(orthology-group)"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/03/26	rogid:Ewj51Zj/ZyWOzFMcnBJT0aX8sh8216597	rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606	intact-crc:8B41DE9E7A65263B|rigid:IjlNBrsS754e1LWXA1RByyOcaLk	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NGY5	uniprotkb:P08134	intact:EBI-10726204	intact:EBI-747589|uniprotkb:Q6ICN3|uniprotkb:B3KSW1|ensembl:ENSP00000285735.2|ensembl:ENSP00000345236.8|ensembl:ENSP00000358646.2|ensembl:ENSP00000358647.2|ensembl:ENSP00000358651.1|ensembl:ENSP00000358652.2|ensembl:ENSP00000358656.3	psi-mi:a0a0h3ngy5_salts(display_long)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)|uniprotkb:G1W50_09785(orf name)|uniprotkb:G1W53_01040(orf name)|uniprotkb:G1W54_01040(orf name)|uniprotkb:G1W56_04395(orf name)|uniprotkb:G1W63_01040(orf name)|uniprotkb:G1W64_06800(orf name)|uniprotkb:G1W86_00720(orf name)|uniprotkb:G1W87_08555(orf name)|uniprotkb:G1W89_03825(orf name)|uniprotkb:G1W92_06230(orf name)|uniprotkb:G1X03_01040(orf name)|uniprotkb:G1X04_00795(orf name)|uniprotkb:G1X09_04135(orf name)|uniprotkb:G1X10_01040(orf name)|uniprotkb:G1X13_04135(orf name)|uniprotkb:G1X17_04135(orf name)|uniprotkb:G1X23_01030(orf name)|uniprotkb:G1X29_04135(orf name)|uniprotkb:G1X32_03720(orf name)|uniprotkb:G1X38_01040(orf name)|uniprotkb:G1X42_06230(orf name)|uniprotkb:G1X47_03705(orf name)|uniprotkb:G1X49_01040(orf name)|uniprotkb:G1X51_04135(orf name)|uniprotkb:G1X52_06805(orf name)|uniprotkb:G1X66_01040(orf name)|uniprotkb:G1X68_01040(orf name)|uniprotkb:G1X69_04400(orf name)|uniprotkb:G1X71_04140(orf name)|uniprotkb:G1X76_01040(orf name)|uniprotkb:G1X80_01040(orf name)|uniprotkb:G1X84_03725(orf name)|uniprotkb:G1X85_01040(orf name)|uniprotkb:G1X86_06485(orf name)|uniprotkb:G1X94_03705(orf name)|uniprotkb:G1X96_06490(orf name)|uniprotkb:G1X99_06815(orf name)|uniprotkb:G1Y02_03725(orf name)|uniprotkb:SL1344_1561(locus name)	psi-mi:rhoc_human(display_long)|uniprotkb:Rho cDNA clone 9(gene name synonym)|uniprotkb:RHOC(gene name)|psi-mi:RHOC(display_short)|uniprotkb:ARH9(gene name synonym)|uniprotkb:ARHC(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690192|imex:IM-25980-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WBW2(uniprot-removed-ac)|refseq:WP_001131430.1|interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0052689""(carboxylic ester hydrolase activity)"	"refseq:NP_001036143.1|refseq:NP_001036144.1|refseq:NP_786886.1|ensembl:ENSG00000155366.17(gene)|ensembl:ENST00000285735.6(transcript)|ensembl:ENST00000339083.12(transcript)|ensembl:ENST00000369632.6(transcript)|ensembl:ENST00000369633.6(transcript)|ensembl:ENST00000369637.5(transcript)|ensembl:ENST00000369638.6(transcript)|ensembl:ENST00000369642.7(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007015""(actin filament organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032420""(stereocilium)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902766""(skeletal muscle satellite cell migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P08134|rcsb pdb:1Z2C|rcsb pdb:2GCN|rcsb pdb:2GCO|rcsb pdb:2GCP|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013106|panther:PTHR24072(orthology-group)"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/27	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY216597	rogid:CPt/q5soDZILGfkngD41Y1U4eys9606	intact-crc:AA0489F994C53ED6|rigid:c/R5YnC3IyIdbB6Cvj+oJ4tx+hM	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NGY5	uniprotkb:P61586	intact:EBI-10726204	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0h3ngy5_salts(display_long)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)|uniprotkb:G1W50_09785(orf name)|uniprotkb:G1W53_01040(orf name)|uniprotkb:G1W54_01040(orf name)|uniprotkb:G1W56_04395(orf name)|uniprotkb:G1W63_01040(orf name)|uniprotkb:G1W64_06800(orf name)|uniprotkb:G1W86_00720(orf name)|uniprotkb:G1W87_08555(orf name)|uniprotkb:G1W89_03825(orf name)|uniprotkb:G1W92_06230(orf name)|uniprotkb:G1X03_01040(orf name)|uniprotkb:G1X04_00795(orf name)|uniprotkb:G1X09_04135(orf name)|uniprotkb:G1X10_01040(orf name)|uniprotkb:G1X13_04135(orf name)|uniprotkb:G1X17_04135(orf name)|uniprotkb:G1X23_01030(orf name)|uniprotkb:G1X29_04135(orf name)|uniprotkb:G1X32_03720(orf name)|uniprotkb:G1X38_01040(orf name)|uniprotkb:G1X42_06230(orf name)|uniprotkb:G1X47_03705(orf name)|uniprotkb:G1X49_01040(orf name)|uniprotkb:G1X51_04135(orf name)|uniprotkb:G1X52_06805(orf name)|uniprotkb:G1X66_01040(orf name)|uniprotkb:G1X68_01040(orf name)|uniprotkb:G1X69_04400(orf name)|uniprotkb:G1X71_04140(orf name)|uniprotkb:G1X76_01040(orf name)|uniprotkb:G1X80_01040(orf name)|uniprotkb:G1X84_03725(orf name)|uniprotkb:G1X85_01040(orf name)|uniprotkb:G1X86_06485(orf name)|uniprotkb:G1X94_03705(orf name)|uniprotkb:G1X96_06490(orf name)|uniprotkb:G1X99_06815(orf name)|uniprotkb:G1Y02_03725(orf name)|uniprotkb:SL1344_1561(locus name)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690192|imex:IM-25980-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WBW2(uniprot-removed-ac)|refseq:WP_001131430.1|interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0052689""(carboxylic ester hydrolase activity)"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/27	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY216597	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:AA0489F994C53ED6|rigid:c/R5YnC3IyIdbB6Cvj+oJ4tx+hM	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NDL6	uniprotkb:P22059	intact:EBI-10726249	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	psi-mi:a0a0h3ndl6_salts(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:SL1344_2256(locus name)	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690222|imex:IM-25980-9	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WCC7(uniprot-removed-ac)|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR054328|interpro:IPR054329"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2024/11/14	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg216597	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	intact-crc:3C5293F2CEE486F4|rigid:661DFYXyvV/gDsdwWFQng6dM0TA	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NF38	uniprotkb:P61981	intact:EBI-10689860	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330.3	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690228|imex:IM-25980-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"efo:""Orphanet:442835""|rcsb pdb:6A5S|rcsb pdb:6BYJ|ensembl:ENSG00000170027.7(gene)|ensembl:ENST00000307630.5(transcript)|go:""GO:0002842""(positive regulation of T cell mediated immune response to tumor cell)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008426""(protein kinase C inhibitor activity)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022409""(positive regulation of cell-cell adhesion)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045664""(regulation of neuron differentiation)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098793""(presynapse)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|rcsb pdb:6ZBT|rcsb pdb:6ZC9|rcsb pdb:7A6R|rcsb pdb:7A6Y|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_036611.2|dip:DIP-33406N|panther:PTHR18860(orthology-group)|ensembl:ENSP00000306330.3"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/28	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	intact-crc:FD5793551AD868BC|rigid:w4PTZEYxb36hx86/6tjLA60aKPY	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NF38	uniprotkb:O43684	intact:EBI-10689860	intact:EBI-1050987|uniprotkb:O43685|uniprotkb:B2R6E7|uniprotkb:A6NJ42|uniprotkb:D3DRE9|ensembl:ENSP00000357858.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:bub3_human(display_long)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690228|imex:IM-25980-11	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"dip:DIP-24205N|ensembl:ENSG00000154473.18(gene)|ensembl:ENST00000368865.9(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008608""(attachment of spindle microtubules to kinetochore)|go:""GO:0033597""(mitotic checkpoint complex)|go:""GO:0034501""(protein localization to kinetochore)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0051301""(cell division)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:1990298""(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43684|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001007794.1|refseq:NP_004716.1|efo:""Orphanet:1052""|panther:PTHR10971(orthology-group)"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/28	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:nqzARPql2cThSUpxSb6PuTRn51E9606	intact-crc:FD5793551AD868BC|rigid:w4PTZEYxb36hx86/6tjLA60aKPY	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NF38	uniprotkb:O95816	intact:EBI-10689860	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|intact:EBI-11068407|ensembl:ENSP00000359727.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690228|imex:IM-25980-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|refseq:XP_011513300.1|ensembl:ENSG00000112208.11(gene)|ensembl:ENST00000370693.5(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0010954""(positive regulation of protein processing)|go:""GO:0019538""(protein metabolic process)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0048156""(tau protein binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1901588""(dendritic microtubule)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|panther:PTHR12334(orthology-group)"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/28	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	intact-crc:FD5793551AD868BC|rigid:w4PTZEYxb36hx86/6tjLA60aKPY	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NF38	uniprotkb:O00170	intact:EBI-10689860	intact:EBI-704197|uniprotkb:Q2M3Q2|uniprotkb:Q99606|uniprotkb:G9I2H4|uniprotkb:A0SZW3|uniprotkb:A0SZW4|uniprotkb:A0SZW5|uniprotkb:A0SZW6|ensembl:ENSP00000279146.3	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:aip_human(display_long)|uniprotkb:Aryl-hydrocarbon receptor-interacting protein(gene name synonym)|uniprotkb:Immunophilin homolog ARA9(gene name synonym)|uniprotkb:HBV X-associated protein 2(gene name synonym)|uniprotkb:AIP(gene name)|psi-mi:AIP(display_short)|uniprotkb:XAP2(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690228|imex:IM-25980-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"efo:""Orphanet:2965""|efo:""Orphanet:314777""|efo:""Orphanet:314786""|efo:""Orphanet:314790""|efo:""Orphanet:963""|efo:""Orphanet:99725""|dip:DIP-34068N|ensembl:ENSG00000110711.11(gene)|ensembl:ENST00000279146.8(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0010738""(regulation of protein kinase A signaling)|go:""GO:0016020""(membrane)|go:""GO:0017162""(aryl hydrocarbon receptor binding)|go:""GO:0022417""(obsolete protein maturation by protein folding)|go:""GO:0034751""(aryl hydrocarbon receptor complex)|go:""GO:0036004""(GAF domain binding)|go:""GO:0051082""(unfolded protein binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039663|interpro:IPR046357|mint:O00170|rcsb pdb:2LKN|rcsb pdb:4AIF|rcsb pdb:4APO|rcsb pdb:7ZUB|rcsb pdb:8QMO|reactome:R-HSA-8937144|reactome:R-HSA-8950505|refseq:NP_001289888.1|refseq:NP_001289889.1|refseq:NP_003968.3|panther:PTHR11242(orthology-group)"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/28	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:5iYsQlXT1uE9cJUUAy1J+weOrLk9606	intact-crc:FD5793551AD868BC|rigid:w4PTZEYxb36hx86/6tjLA60aKPY	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y2Z0	intact:EBI-10689860	intact:EBI-307008|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6|ensembl:ENSP00000367208.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690228|imex:IM-25980-11	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"refseq:NP_001124384.1|refseq:NP_006695.1|ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000343788.10(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007051""(spindle organization)|go:""GO:0014841""(skeletal muscle satellite cell proliferation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032991""(protein-containing complex)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0106222""(lncRNA binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|reactome:R-HSA-9660826|refseq:NP_001307760.1|dip:DIP-53799N|panther:PTHR45862(orthology-group)"	-	-	-	figure legend:4 and table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/28	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	intact-crc:FD5793551AD868BC|rigid:w4PTZEYxb36hx86/6tjLA60aKPY	false	ha tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:A0A0H3NA16	uniprotkb:P60953	intact:EBI-10726187	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:a0a0h3na16_salts(display_long)|uniprotkb:G1X32_21660(orf name)|uniprotkb:G1X38_21955(orf name)|uniprotkb:G1X42_20695(orf name)|uniprotkb:G1X47_21385(orf name)|uniprotkb:G1X49_21885(orf name)|uniprotkb:G1X51_21455(orf name)|uniprotkb:G1X52_21395(orf name)|uniprotkb:G1X66_21475(orf name)|uniprotkb:G1X68_18020(orf name)|uniprotkb:G1X69_21975(orf name)|uniprotkb:G1X71_21710(orf name)|uniprotkb:G1X76_21360(orf name)|uniprotkb:G1X80_21495(orf name)|uniprotkb:G1X84_21405(orf name)|uniprotkb:G1X85_20930(orf name)|uniprotkb:G1X86_21700(orf name)|uniprotkb:G1X94_21565(orf name)|uniprotkb:G1X96_21705(orf name)|uniprotkb:G1X99_21920(orf name)|uniprotkb:G1Y02_21400(orf name)|uniprotkb:SL1344_1030(locus name)|uniprotkb:sopB(gene name)|psi-mi:sopB(display_short)|uniprotkb:Effector protein SopB(gene name synonym)|uniprotkb:sigD(gene name synonym)|uniprotkb:G1W50_21240(orf name)|uniprotkb:G1W53_21100(orf name)|uniprotkb:G1W54_21690(orf name)|uniprotkb:G1W56_21065(orf name)|uniprotkb:G1W63_21110(orf name)|uniprotkb:G1W64_21805(orf name)|uniprotkb:G1W86_20115(orf name)|uniprotkb:G1W87_20995(orf name)|uniprotkb:G1W89_20265(orf name)|uniprotkb:G1W92_20690(orf name)|uniprotkb:G1X03_20885(orf name)|uniprotkb:G1X04_08935(orf name)|uniprotkb:G1X09_22275(orf name)|uniprotkb:G1X10_21625(orf name)|uniprotkb:G1X13_21700(orf name)|uniprotkb:G1X17_22505(orf name)|uniprotkb:G1X23_21605(orf name)|uniprotkb:G1X29_21410(orf name)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690579|imex:IM-25980-13	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1W7C2(uniprot-removed-ac)|refseq:WP_001166946.1|interpro:IPR008108(Type III secretion system outer membrane, B protein)|go:""GO:0005576""(extracellular region)|go:""GO:0016791""(phosphatase activity)"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	-	-	-	figure legend:4 and table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/12	2024/11/07	rogid:UQwDH+y4MXGRiHj5Fn4PM/N6afI216597	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:514F4A56FD0A3FB8|rigid:3+6MfJSgUABTq8JG8/8Icx/cUEY	false	ha tag:n-n|glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q9Y2Z0	uniprotkb:A0A0H3NF38	intact:EBI-307008|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6|ensembl:ENSP00000367208.4	intact:EBI-10689860	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690607|imex:IM-25980-21	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001124384.1|refseq:NP_006695.1|ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000343788.10(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007051""(spindle organization)|go:""GO:0014841""(skeletal muscle satellite cell proliferation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032991""(protein-containing complex)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0106222""(lncRNA binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|reactome:R-HSA-9660826|refseq:NP_001307760.1|dip:DIP-53799N|panther:PTHR45862(orthology-group)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	-	-	-	figure legend:6A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/27	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	intact-crc:0C0F4A9C01678E3E|rigid:4rkY4BDd6G7qOY5GxqK9Y4odu4A	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NDL6	uniprotkb:P22059	intact:EBI-10726249	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	psi-mi:a0a0h3ndl6_salts(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:SL1344_2256(locus name)	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690611|imex:IM-25980-23	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WCC7(uniprot-removed-ac)|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR054328|interpro:IPR054329"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	-	-	-	figure legend:6B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2024/11/14	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg216597	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	intact-crc:3F08F1854074A26B|rigid:661DFYXyvV/gDsdwWFQng6dM0TA	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NDL6	uniprotkb:P22059	intact:EBI-10726249	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	psi-mi:a0a0h3ndl6_salts(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:SL1344_2256(locus name)	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690615|imex:IM-25980-15	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:E1WCC7(uniprot-removed-ac)|go:""GO:0005576""(extracellular region)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR054328|interpro:IPR054329"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	-	-	-	figure legend:6B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2024/11/14	rogid:AJQzdgPf/zGzoZSe4RbJPo44MEg216597	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	intact-crc:9218701749C0F467|rigid:661DFYXyvV/gDsdwWFQng6dM0TA	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:O43684	intact:EBI-10689860	intact:EBI-1050987|uniprotkb:O43685|uniprotkb:B2R6E7|uniprotkb:A6NJ42|uniprotkb:D3DRE9|ensembl:ENSP00000357858.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:bub3_human(display_long)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690619|imex:IM-25980-17	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"dip:DIP-24205N|ensembl:ENSG00000154473.18(gene)|ensembl:ENST00000368865.9(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008608""(attachment of spindle microtubules to kinetochore)|go:""GO:0033597""(mitotic checkpoint complex)|go:""GO:0034501""(protein localization to kinetochore)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0051301""(cell division)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:1990298""(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43684|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001007794.1|refseq:NP_004716.1|efo:""Orphanet:1052""|panther:PTHR10971(orthology-group)"	-	-	-	figure legend:Figs. 6A, 6C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/27	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:nqzARPql2cThSUpxSb6PuTRn51E9606	intact-crc:3BF7A22191918748|rigid:rjMbKIRJpcqRSSjqUeuMkaArZzo	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:Q9Y2Z0	intact:EBI-10689860	intact:EBI-307008|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6|ensembl:ENSP00000367208.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690619|imex:IM-25980-17	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"refseq:NP_001124384.1|refseq:NP_006695.1|ensembl:ENSG00000165416.15(gene)|ensembl:ENST00000343788.10(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007051""(spindle organization)|go:""GO:0014841""(skeletal muscle satellite cell proliferation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032991""(protein-containing complex)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0106222""(lncRNA binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|reactome:R-HSA-9660826|refseq:NP_001307760.1|dip:DIP-53799N|panther:PTHR45862(orthology-group)"	-	-	-	figure legend:Figs. 6A, 6C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/27	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606	intact-crc:3BF7A22191918748|rigid:rjMbKIRJpcqRSSjqUeuMkaArZzo	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0H3NF38	uniprotkb:O43684	intact:EBI-10689860	intact:EBI-1050987|uniprotkb:O43685|uniprotkb:B2R6E7|uniprotkb:A6NJ42|uniprotkb:D3DRE9|ensembl:ENSP00000357858.4	psi-mi:a0a0h3nf38_salts(display_long)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:G1W50_06135(orf name)|uniprotkb:G1W92_13600(orf name)|uniprotkb:G1X04_24335(orf name)|uniprotkb:G1X42_13600(orf name)|uniprotkb:SL1344_2217(locus name)	psi-mi:bub3_human(display_long)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Auweter et al. (2011)	pubmed:21566117|imex:IM-25980	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10690623|imex:IM-25980-19	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|uniprotkb:E1WC83(uniprot-removed-ac)|refseq:WP_001115840.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030430""(host cell cytoplasm)"	"dip:DIP-24205N|ensembl:ENSG00000154473.18(gene)|ensembl:ENST00000368865.9(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008608""(attachment of spindle microtubules to kinetochore)|go:""GO:0033597""(mitotic checkpoint complex)|go:""GO:0034501""(protein localization to kinetochore)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0051301""(cell division)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:1990298""(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43684|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001007794.1|refseq:NP_004716.1|efo:""Orphanet:1052""|panther:PTHR10971(orthology-group)"	-	-	-	figure legend:6C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2015/03/12	2025/02/27	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA216597	rogid:nqzARPql2cThSUpxSb6PuTRn51E9606	intact-crc:C1700DA7524E430A|rigid:p3VjzZDgpG8B0HaS87vxMP539bY	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61586	intact:EBI-10760263	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:0077""(nuclear magnetic resonance)"	LaRock et al. (2012)	pubmed:22740689|imex:IM-24065	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10705826|imex:IM-24065-4	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	-	-	-	figure legend:2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/16	2025/02/27	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:8A767E4C6AE6E450	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61586	intact:EBI-10760263	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:0077""(nuclear magnetic resonance)"	LaRock et al. (2012)	pubmed:22740689|imex:IM-24065	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10760327|imex:IM-24065-7	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	-	-	-	figure legend:2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/16	2025/02/27	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:9738EE73C4AB1046	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61586	intact:EBI-10760263	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	LaRock et al. (2012)	pubmed:22740689|imex:IM-24065	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10705840|imex:IM-24065-1	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	-	-	-	figure legend:3B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/16	2025/02/27	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:3BE6E2EE9C39DC19|rigid:V/oBMsbo/9D4Lk4ynrSuTOIuD88	false	glutathione s tranferase tag:n-n	his tag:n-n|mutation disrupting interaction:39-39|mutation disrupting interaction:68-68|mutation decreasing interaction:69-69|mutation disrupting interaction:72-72|mutation disrupting interaction:106-106|mutation:14-14	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P61586	uniprotkb:A0A0F6B1Q8	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	intact:EBI-10760263	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	"psi-mi:""MI:0416""(fluorescence microscopy)"	LaRock et al. (2012)	pubmed:22740689|imex:IM-24065	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10705866|imex:IM-24065-3	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"go:""GO:0044174""(host cell endosome)"	-	-	figure legend:4A and S2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2015/03/16	2025/02/27	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	intact-crc:2D73955C088307C4|rigid:V/oBMsbo/9D4Lk4ynrSuTOIuD88	false	ha tag:?-?|mutation:14-14	myc tag:?-?|mutation decreasing interaction:121-121	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61586	intact:EBI-10760263	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:1354""(lipase assay)"	LaRock et al. (2012)	pubmed:22740689|imex:IM-24065	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:1355""(lipid cleavage)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10760280|imex:IM-24065-8	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0684""(ancillary)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"go:""GO:0016298""(lipase activity)"	-	-	figure legend:1 and S1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/16	2025/02/27	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:067A8CA954BD7708	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61586	intact:EBI-10760263	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:1354""(lipase assay)"	LaRock et al. (2012)	pubmed:22740689|imex:IM-24065	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:1355""(lipid cleavage)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10760295|imex:IM-24065-6	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0684""(ancillary)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"go:""GO:0016298""(lipase activity)"	-	-	figure legend:3A and suppl table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/16	2025/02/27	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:5C85946DA73E3477	false	-	his tag:?-?|mutation:14-14|mutation decreasing interaction:39-39|mutation disrupting interaction:68-68|mutation decreasing interaction:69-69|mutation decreasing interaction:72-72|mutation decreasing interaction:106-106|mutation disrupting interaction:72-72,39-39	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0F6B1Q8	uniprotkb:P61586	intact:EBI-10760263	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:1354""(lipase assay)"	LaRock et al. (2012)	pubmed:22740689|imex:IM-24065	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:1355""(lipid cleavage)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10815133|imex:IM-24065-10	intact-miscore:0.74	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0684""(ancillary)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"go:""GO:0016298""(lipase activity)"	-	-	figure legend:1 and S1|comment:SseJ also competes with the Rho effector binding domains, PKN1 and ROCK, for binding Rho.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/16	2025/02/27	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:D4BFD6FDD51BB1B4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A0F6B1Q8	uniprotkb:Q9BST9	intact:EBI-10760263	intact:EBI-446694|uniprotkb:Q8WVN1|uniprotkb:Q96PT6|uniprotkb:Q9HB05|ensembl:ENSP00000272430.5|uniprotkb:H7BXD4|intact:EBI-28972758	psi-mi:a0a0f6b1q8_salt1(display_long)|uniprotkb:STM14_1974(locus name)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)	psi-mi:rtkn_human(display_long)|uniprotkb:RTKN1(gene name synonym)|uniprotkb:RTKN(gene name)|psi-mi:RTKN(display_short)	"psi-mi:""MI:1354""(lipase assay)"	LaRock et al. (2012)	pubmed:22740689|imex:IM-24065	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:1355""(lipid cleavage)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10815133|imex:IM-24065-10	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|refseq:WP_001131430.1|uniprotkb:D0ZI42(uniprot-removed-ac)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044184""(host cell late endosome)|go:""GO:0052025""(symbiont-mediated perturbation of host cell endomembrane system)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|mint:A0A0F6B1Q8"	"refseq:NP_001015055.1|refseq:NP_001015056.1|refseq:NP_149035.1|ensembl:ENSG00000114993.17(gene)|ensembl:ENST00000272430.10(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0000915""(actomyosin contractile ring assembly)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005826""(actomyosin contractile ring)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0031106""(septin ring organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0042981""(regulation of apoptotic process)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012966(Protein of unknown function DUF1709, fungi)|interpro:IPR051364|mint:Q9BST9|reactome:R-HSA-5666185|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|refseq:XP_016860124.1|dip:DIP-31098N|panther:PTHR21538(orthology-group)"	"go:""GO:0016298""(lipase activity)"	-	-	figure legend:1 and S1|comment:SseJ also competes with the Rho effector binding domains, PKN1 and ROCK, for binding Rho.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/16	2025/02/27	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY588858	rogid:Bep3YojtNr0rbW7zImG6oXyrQHw9606	intact-crc:D4BFD6FDD51BB1B4	false	-	glutathione s tranferase tag:?-?|sufficient binding region:7-89	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P22059	uniprotkb:Q8ZNG2	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	intact:EBI-10690213	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	psi-mi:ssel_salty(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM2287(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Auweter et al. (2012)	pubmed:21988961|imex:IM-25856	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10710869|imex:IM-25856-1	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	"refseq:NP_461229.3|dip:DIP-60877N|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR054328|interpro:IPR054329|rcsb pdb:5HAF|rcsb pdb:5UBW|refseq:WP_014343870.1"	-	-	-	figure legend:1A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/18	2024/11/14	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	rogid:6O8jaE4X2YnyB3QeVBjyWjESMLM99287	intact-crc:3574DF90AA58E07A|rigid:xL+ceJi4mw5Baz/pUvfWo2T8rQU	false	-	ha tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P22059	uniprotkb:Q8ZNG2	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	intact:EBI-10690213	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	psi-mi:ssel_salty(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM2287(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2012)	pubmed:21988961|imex:IM-25856	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10710881|imex:IM-25856-3	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	"refseq:NP_461229.3|dip:DIP-60877N|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR054328|interpro:IPR054329|rcsb pdb:5HAF|rcsb pdb:5UBW|refseq:WP_014343870.1"	-	-	-	figure legend:1A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/18	2024/11/14	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	rogid:6O8jaE4X2YnyB3QeVBjyWjESMLM99287	intact-crc:513C165B47CEEC50|rigid:xL+ceJi4mw5Baz/pUvfWo2T8rQU	false	-	ha tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P22059	uniprotkb:Q8ZNG2	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	intact:EBI-10690213	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	psi-mi:ssel_salty(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM2287(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2012)	pubmed:21988961|imex:IM-25856	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10710894|imex:IM-25856-5	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	"refseq:NP_461229.3|dip:DIP-60877N|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR054328|interpro:IPR054329|rcsb pdb:5HAF|rcsb pdb:5UBW|refseq:WP_014343870.1"	-	-	-	figure legend:1C-D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/18	2024/11/14	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	rogid:6O8jaE4X2YnyB3QeVBjyWjESMLM99287	intact-crc:0FBBC892D7A417E1|rigid:xL+ceJi4mw5Baz/pUvfWo2T8rQU	false	flag tag:?-?|sufficient binding region:182-415	ha tag:?-?	-	-	"psi-mi:""MI:0707""(anti tag immunostaining)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:P22059	uniprotkb:Q8ZNG2	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847.1	intact:EBI-10690213	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	psi-mi:ssel_salty(display_long)|uniprotkb:sseL(gene name)|psi-mi:sseL(display_short)|uniprotkb:Deubiquitinating enzyme(gene name synonym)|uniprotkb:Deubiquitinating protease(gene name synonym)|uniprotkb:Salmonella secreted effector L(gene name synonym)|uniprotkb:STM2287(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Auweter et al. (2012)	pubmed:21988961|imex:IM-25856	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10710905|imex:IM-25856-7	intact-miscore:0.52	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002547.1|ensembl:ENSG00000110048.12(gene)|ensembl:ENST00000263847.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008142""(oxysterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030054""(cell junction)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032934""(sterol binding)|go:""GO:0035627""(ceramide transport)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|go:""GO:1904411""(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:P22059|rcsb pdb:2RR3|rcsb pdb:7V62|reactome:R-HSA-1660661|reactome:R-HSA-192105|panther:PTHR10972(orthology-group)"	"refseq:NP_461229.3|dip:DIP-60877N|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR054328|interpro:IPR054329|rcsb pdb:5HAF|rcsb pdb:5UBW|refseq:WP_014343870.1"	-	-	-	figure legend:1C-D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/18	2024/11/14	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	rogid:6O8jaE4X2YnyB3QeVBjyWjESMLM99287	intact-crc:C91AE7E4C1EB61AA|rigid:xL+ceJi4mw5Baz/pUvfWo2T8rQU	false	flag tag:?-?|sufficient binding region:182-415	ha tag:?-?	-	-	"psi-mi:""MI:0707""(anti tag immunostaining)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:P61586	uniprotkb:Q9FD10	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	intact:EBI-10690199|uniprotkb:Q7BIM8	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	psi-mi:ssej_salty(display_long)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)|uniprotkb:Salmonella-translocated effector J(gene name synonym)|uniprotkb:STM1631(locus name)	"psi-mi:""MI:0428""(imaging technique)"	Christen et al. (2008)	pubmed:19887681|imex:IM-25846	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10710933|imex:IM-25846-1	intact-miscore:0.53	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"refseq:NP_460590.1|refseq:WP_001131430.1|interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0016298""(lipase activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0033644""(host cell membrane)|go:""GO:0034736""(cholesterol O-acyltransferase activity)|go:""GO:0044174""(host cell endosome)|go:""GO:0047178""(""glycerophospholipid acyltransferase (CoA-dependent) activity"")|panther:PTHR45642(orthology-group)"	"go:""GO:0031982""(vesicle)"	-	-	figure legend:1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2015/03/18	2025/02/27	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY99287	intact-crc:BE040822E85035AB|rigid:ICO1+3xi/u9JFsRTLk+sHszRfy0	false	myc tag:n-n	ha tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P61586	uniprotkb:Q9FD10	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	intact:EBI-10690199|uniprotkb:Q7BIM8	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	psi-mi:ssej_salty(display_long)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)|uniprotkb:Salmonella-translocated effector J(gene name synonym)|uniprotkb:STM1631(locus name)	"psi-mi:""MI:0071""(molecular sieving)"	Christen et al. (2008)	pubmed:19887681|imex:IM-25846	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10710948|imex:IM-25846-3	intact-miscore:0.53	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"refseq:NP_460590.1|refseq:WP_001131430.1|interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0016298""(lipase activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0033644""(host cell membrane)|go:""GO:0034736""(cholesterol O-acyltransferase activity)|go:""GO:0044174""(host cell endosome)|go:""GO:0047178""(""glycerophospholipid acyltransferase (CoA-dependent) activity"")|panther:PTHR45642(orthology-group)"	-	-	-	figure legend:2A|comment:SseJ binds with GTPgS loaded RhoA|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/18	2025/02/27	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY99287	intact-crc:DAC3C699D1BE9F19|rigid:ICO1+3xi/u9JFsRTLk+sHszRfy0	false	his tag:n-n	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08134	uniprotkb:Q9FD10	intact:EBI-747589|uniprotkb:Q6ICN3|uniprotkb:B3KSW1|ensembl:ENSP00000285735.2|ensembl:ENSP00000345236.8|ensembl:ENSP00000358646.2|ensembl:ENSP00000358647.2|ensembl:ENSP00000358651.1|ensembl:ENSP00000358652.2|ensembl:ENSP00000358656.3	intact:EBI-10690199|uniprotkb:Q7BIM8	psi-mi:rhoc_human(display_long)|uniprotkb:Rho cDNA clone 9(gene name synonym)|uniprotkb:RHOC(gene name)|psi-mi:RHOC(display_short)|uniprotkb:ARH9(gene name synonym)|uniprotkb:ARHC(gene name synonym)	psi-mi:ssej_salty(display_long)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)|uniprotkb:Salmonella-translocated effector J(gene name synonym)|uniprotkb:STM1631(locus name)	"psi-mi:""MI:0071""(molecular sieving)"	Christen et al. (2008)	pubmed:19887681|imex:IM-25846	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10710959|imex:IM-25846-5	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001036143.1|refseq:NP_001036144.1|refseq:NP_786886.1|ensembl:ENSG00000155366.17(gene)|ensembl:ENST00000285735.6(transcript)|ensembl:ENST00000339083.12(transcript)|ensembl:ENST00000369632.6(transcript)|ensembl:ENST00000369633.6(transcript)|ensembl:ENST00000369637.5(transcript)|ensembl:ENST00000369638.6(transcript)|ensembl:ENST00000369642.7(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007015""(actin filament organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032420""(stereocilium)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902766""(skeletal muscle satellite cell migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P08134|rcsb pdb:1Z2C|rcsb pdb:2GCN|rcsb pdb:2GCO|rcsb pdb:2GCP|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013106|panther:PTHR24072(orthology-group)"	"refseq:NP_460590.1|refseq:WP_001131430.1|interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0016298""(lipase activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0033644""(host cell membrane)|go:""GO:0034736""(cholesterol O-acyltransferase activity)|go:""GO:0044174""(host cell endosome)|go:""GO:0047178""(""glycerophospholipid acyltransferase (CoA-dependent) activity"")|panther:PTHR45642(orthology-group)"	-	-	-	figure legend:S1|comment:SseJ binds with GTPgS loaded RhoA|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/18	2024/11/14	rogid:CPt/q5soDZILGfkngD41Y1U4eys9606	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY99287	intact-crc:A5CA1F0840D26625|rigid:rcT2KYO7vq6T4ate9/tcKezqkX0	false	his tag:n-n	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P61586	uniprotkb:Q9FD10	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	intact:EBI-10690199|uniprotkb:Q7BIM8	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	psi-mi:ssej_salty(display_long)|uniprotkb:sseJ(gene name)|psi-mi:sseJ(display_short)|uniprotkb:Salmonella-translocated effector J(gene name synonym)|uniprotkb:STM1631(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Christen et al. (2008)	pubmed:19887681|imex:IM-25846	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10710970|imex:IM-25846-7	intact-miscore:0.53	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"refseq:NP_460590.1|refseq:WP_001131430.1|interpro:IPR001087(Lipase, GDSL)|interpro:IPR010637(Sif)|interpro:IPR036514|go:""GO:0005576""(extracellular region)|go:""GO:0016298""(lipase activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0033644""(host cell membrane)|go:""GO:0034736""(cholesterol O-acyltransferase activity)|go:""GO:0044174""(host cell endosome)|go:""GO:0047178""(""glycerophospholipid acyltransferase (CoA-dependent) activity"")|panther:PTHR45642(orthology-group)"	"go:""GO:0047178""(""glycerophospholipid acyltransferase (CoA-dependent) activity"")"	-	-	figure legend:1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2015/03/18	2025/02/27	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	rogid:6GFdi+/W/KwPYpF9gMheJlErYXY99287	intact-crc:E260588E97E5E7D2|rigid:ICO1+3xi/u9JFsRTLk+sHszRfy0	false	ha tag:?-?	myc tag:n-n	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:Q9UBS4	uniprotkb:Q8ZQQ2	intact:EBI-713113|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6|ensembl:ENSP00000265028.3|ensembl:ENSP00000414398.1	intact:EBI-10712653|uniprotkb:Q9XCV2	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:slrp_salty(display_long)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM0800(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Bernal-Bayard et al. (2010)	imex:IM-24457|pubmed:20335166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10712651|imex:IM-24457-1	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090520.12(gene)|ensembl:ENST00000265028.8(transcript)|ensembl:ENST00000439351.5(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006457""(protein folding)|go:""GO:0016020""(membrane)|go:""GO:0016556""(mRNA modification)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051604""(protein maturation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0101031""(protein folding chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|interpro:IPR051736|mint:Q9UBS4|reactome:R-HSA-381038|refseq:NP_057390.1|efo:""Orphanet:730""|dip:DIP-29678N|panther:PTHR44298(orthology-group)"	"refseq:NP_459778.1|interpro:IPR051071|refseq:WP_000482001.1|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0051082""(unfolded protein binding)|panther:PTHR47114(orthology-group)"	-	-	-	figure legend:1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/03/19	2025/03/01	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rogid:VcpuNuh0sBYsHVhTPglpWjVk9Nc99287	intact-crc:A57920D5E785CCD4|rigid:JxShW4ExDgIElYRmEmL4/YE0w6k	false	necessary binding region:161-200	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UBS4	uniprotkb:Q8ZQQ2	intact:EBI-713113|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6|ensembl:ENSP00000265028.3|ensembl:ENSP00000414398.1	intact:EBI-10712653|uniprotkb:Q9XCV2	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:slrp_salty(display_long)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM0800(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Bernal-Bayard et al. (2010)	imex:IM-24457|pubmed:20335166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10713456|imex:IM-24457-8	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090520.12(gene)|ensembl:ENST00000265028.8(transcript)|ensembl:ENST00000439351.5(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006457""(protein folding)|go:""GO:0016020""(membrane)|go:""GO:0016556""(mRNA modification)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051604""(protein maturation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0101031""(protein folding chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|interpro:IPR051736|mint:Q9UBS4|reactome:R-HSA-381038|refseq:NP_057390.1|efo:""Orphanet:730""|dip:DIP-29678N|panther:PTHR44298(orthology-group)"	"refseq:NP_459778.1|interpro:IPR051071|refseq:WP_000482001.1|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0051082""(unfolded protein binding)|panther:PTHR47114(orthology-group)"	-	-	-	figure legend:2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/19	2025/03/01	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rogid:VcpuNuh0sBYsHVhTPglpWjVk9Nc99287	intact-crc:9A5E97A280177E0D|rigid:JxShW4ExDgIElYRmEmL4/YE0w6k	false	necessary binding region:161-200|glutathione s tranferase tag:n-n	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9UBS4	uniprotkb:Q8ZQQ2	intact:EBI-713113|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6|ensembl:ENSP00000265028.3|ensembl:ENSP00000414398.1	intact:EBI-10712653|uniprotkb:Q9XCV2	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:slrp_salty(display_long)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM0800(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Bernal-Bayard et al. (2010)	imex:IM-24457|pubmed:20335166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10713471|imex:IM-24457-5	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090520.12(gene)|ensembl:ENST00000265028.8(transcript)|ensembl:ENST00000439351.5(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006457""(protein folding)|go:""GO:0016020""(membrane)|go:""GO:0016556""(mRNA modification)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051604""(protein maturation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0101031""(protein folding chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|interpro:IPR051736|mint:Q9UBS4|reactome:R-HSA-381038|refseq:NP_057390.1|efo:""Orphanet:730""|dip:DIP-29678N|panther:PTHR44298(orthology-group)"	"refseq:NP_459778.1|interpro:IPR051071|refseq:WP_000482001.1|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0051082""(unfolded protein binding)|panther:PTHR47114(orthology-group)"	-	-	-	figure legend:3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2015/03/19	2025/03/01	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rogid:VcpuNuh0sBYsHVhTPglpWjVk9Nc99287	intact-crc:2D41FDD62A0386BF|rigid:JxShW4ExDgIElYRmEmL4/YE0w6k	false	ha tag:c-c	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9UBS4	uniprotkb:Q8ZQQ2	intact:EBI-713113|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6|ensembl:ENSP00000265028.3|ensembl:ENSP00000414398.1	intact:EBI-10712653|uniprotkb:Q9XCV2	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:slrp_salty(display_long)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM0800(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	"psi-mi:""MI:0663""(confocal microscopy)"	Bernal-Bayard et al. (2010)	imex:IM-24457|pubmed:20335166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10713488|imex:IM-24457-7	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090520.12(gene)|ensembl:ENST00000265028.8(transcript)|ensembl:ENST00000439351.5(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006457""(protein folding)|go:""GO:0016020""(membrane)|go:""GO:0016556""(mRNA modification)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051604""(protein maturation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0101031""(protein folding chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|interpro:IPR051736|mint:Q9UBS4|reactome:R-HSA-381038|refseq:NP_057390.1|efo:""Orphanet:730""|dip:DIP-29678N|panther:PTHR44298(orthology-group)"	"refseq:NP_459778.1|interpro:IPR051071|refseq:WP_000482001.1|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0044165""(host cell endoplasmic reticulum)|go:""GO:0051082""(unfolded protein binding)|panther:PTHR47114(orthology-group)"	"go:""GO:0044165""(host cell endoplasmic reticulum)"	-	-	figure legend:4A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2015/03/19	2025/03/01	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rogid:VcpuNuh0sBYsHVhTPglpWjVk9Nc99287	intact-crc:467308399069022D|rigid:JxShW4ExDgIElYRmEmL4/YE0w6k	false	ha tag:c-c	flag tag:c-c	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
intact:EBI-10706085	uniprotkb:Q6K0P9	-	intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122.1	psi-mi:isd(display_short)|psi-mi:EBI-10706085(display_long)	psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym)	"psi-mi:""MI:0413""(electrophoretic mobility shift assay)"	Diner et al. (2015)	imex:IM-23523|pubmed:25665578	"taxid:169963(lismo)|taxid:169963(""Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10706081|imex:IM-23523-5	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0681""(double stranded deoxyribonucleic acid)"	"psi-mi:""MI:0326""(protein)"	-	"refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564.15(gene)|ensembl:ENST00000368140.6(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0016607""(nuclear speck)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035457""(cellular response to interferon-alpha)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0050821""(protein stabilization)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902164""(obsolete positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040205|panther:PTHR12200(orthology-group)"	-	-	-	figure legend:Fig. 6A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/12/04	2024/11/14	-	rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606	intact-crc:65C2B43CB9F22264	false	biotin tag:?-?	sufficient binding region:200-492|glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:Q6K0P9	intact:EBI-10706085	intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122.1	-	psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym)	psi-mi:isd(display_short)|psi-mi:EBI-10706085(display_long)	"psi-mi:""MI:0413""(electrophoretic mobility shift assay)"	Diner et al. (2015)	imex:IM-23523|pubmed:25665578	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:169963(lismo)|taxid:169963(""Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10706106|imex:IM-23523-6	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0681""(double stranded deoxyribonucleic acid)"	"refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564.15(gene)|ensembl:ENST00000368140.6(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0016607""(nuclear speck)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035457""(cellular response to interferon-alpha)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0050821""(protein stabilization)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902164""(obsolete positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040205|panther:PTHR12200(orthology-group)"	-	-	-	-	figure legend:Fig. 6A, 6B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/12/04	2024/11/14	rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606	-	intact-crc:EF5764C4CEB8BD9E	false	sufficient binding region:200-492|glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:Q6K0P9	intact:EBI-10706085	intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122.1	-	psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym)	psi-mi:isd(display_short)|psi-mi:EBI-10706085(display_long)	"psi-mi:""MI:0413""(electrophoretic mobility shift assay)"	Diner et al. (2015)	imex:IM-23523|pubmed:25665578	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:169963(lismo)|taxid:169963(""Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10706106|imex:IM-23523-6	intact-miscore:0.54	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0681""(double stranded deoxyribonucleic acid)"	"refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564.15(gene)|ensembl:ENST00000368140.6(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0016607""(nuclear speck)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035457""(cellular response to interferon-alpha)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0050821""(protein stabilization)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902164""(obsolete positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040205|panther:PTHR12200(orthology-group)"	-	-	-	-	figure legend:Fig. 6A, 6B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/12/04	2024/11/14	rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606	-	intact-crc:EF5764C4CEB8BD9E	false	sufficient binding region:200-492|glutathione s tranferase tag:?-?	biotin tag:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:O43257	uniprotkb:Q8XA11	intact:EBI-347522|ensembl:ENSP00000304593.2|uniprotkb:Q6IB12	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	psi-mi:znhi1_human(display_long)|uniprotkb:Cyclin-G1-binding protein 1(gene name synonym)|uniprotkb:Zinc finger protein subfamily 4A member 1(gene name synonym)|uniprotkb:p18 Hamlet(gene name synonym)|uniprotkb:ZNHIT1(gene name)|psi-mi:ZNHIT1(display_short)|uniprotkb:CGBP1(gene name synonym)|uniprotkb:ZNFN4A1(gene name synonym)	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040272|imex:IM-23549-85	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106400.12(gene)|ensembl:ENST00000305105.3(transcript)|go:""GO:0000786""(nucleosome)|go:""GO:0000812""(Swr1 complex)|go:""GO:0003015""(heart process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0031491""(nucleosome binding)|go:""GO:0036335""(intestinal stem cell homeostasis)|go:""GO:0042393""(histone binding)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:1902164""(obsolete positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:1905458""(positive regulation of lymphoid progenitor cell differentiation)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR039723|mint:O43257|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|refseq:NP_006340.1|panther:PTHR13093(orthology-group)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:Q7J5KSTTPql/B3mtDg1xvX0EWjw9606	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	intact-crc:3FFF6DCAD9E8DBEF|rigid:ZKzZi/Z6g5p/LPvOaXKz67zdspg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8XAJ5	uniprotkb:Q93096	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	intact:EBI-1058467|uniprotkb:O00648|uniprotkb:Q49A54|uniprotkb:B2R6C8|intact:EBI-1640492|ensembl:ENSP00000485687.1|ensembl:ENSP00000497588.1|ensembl:ENSP00000500859.1|ensembl:ENSP00000500952.1|intact:EBI-21351791	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	"psi-mi:tp4a1_human(display_long)|uniprotkb:PTP4A1(gene name)|psi-mi:PTP4A1(display_short)|uniprotkb:PRL1(gene name synonym)|uniprotkb:PTPCAAX1(gene name synonym)|uniprotkb:""PTP(CAAXI)""(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 4a1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase of regenerating liver 1(gene name synonym)"	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040239|imex:IM-23549-75	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001025672.1|refseq:NP_309839.1	"refseq:NP_003454.1|refseq:XP_016866759.1|refseq:XP_016866760.1|ensembl:ENSG00000112245.14(gene)|ensembl:ENST00000626021.3(transcript)|ensembl:ENST00000648894.1(transcript)|ensembl:ENST00000672924.1(transcript)|ensembl:ENST00000673199.1(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005819""(spindle)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR020422|interpro:IPR029021|interpro:IPR050561|mint:Q93096|rcsb pdb:1RXD|rcsb pdb:1XM2|rcsb pdb:5BX1|refseq:XP_011534413.1|refseq:XP_011534414.1|panther:PTHR23339(orthology-group)"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	rogid:Eza5NsYNd+5ml6QEEmkQv5pAZ789606	intact-crc:5613EA756E190DB0|rigid:34CyLoE6+8jRAPYLPlLJhU14uWc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8XAL7	uniprotkb:P05204	intact:EBI-10039292|uniprotkb:Q7AEM9	intact:EBI-1758689|uniprotkb:Q0VGD5|uniprotkb:Q6FGI5|uniprotkb:Q96C64|ensembl:ENSP00000355228.5	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	psi-mi:hmgn2_human(display_long)|uniprotkb:HMGN2(gene name)|psi-mi:HMGN2(display_short)|uniprotkb:HMG17(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040268|imex:IM-23549-84	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	"refseq:NP_005508.1|ensembl:ENSG00000198830.13(gene)|ensembl:ENST00000361427.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05204|panther:PTHR23087(orthology-group)"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	rogid:j8Khsp7BUJh0L9SicpVNR8LP6ZU9606	intact-crc:3748E4EFF0E0D0A2|rigid:PF/SuX8AHZOi79VBEk4FrlTd2hE	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7DB50	uniprotkb:Q13287	intact:EBI-6379656|uniprotkb:Q7A9M3|uniprotkb:A0A6M0JN46	intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|ensembl:ENSP00000243346.5|uniprotkb:B5BU69	psi-mi:q7db50_eco57(display_long)|uniprotkb:espG(gene name)|psi-mi:espG(display_short)|uniprotkb:ECs_4590(orf name)	psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040213|imex:IM-23549-67	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009669(EspG)|rcsb pdb:3PCR|rcsb pdb:3PCS|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|refseq:WP_001301460.1|interpro:IPR043098|go:""GO:0004197""(cysteine-type endopeptidase activity)|refseq:NP_312617.1"	"ensembl:ENSG00000123609.11(gene)|ensembl:ENST00000243346.10(transcript)|go:""GO:0002281""(macrophage activation involved in immune response)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0032687""(negative regulation of interferon-alpha production)|go:""GO:0032688""(negative regulation of interferon-beta production)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902524""(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q13287|reactome:R-HSA-9692916|refseq:NP_004679.2|refseq:XP_005246998.1|refseq:XP_016860736.1|panther:PTHR15225(orthology-group)"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:g7FQ+G0CKEqSrzN+2H+OAnLu7No83334	rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606	intact-crc:B08C85BA2F97E53D|rigid:ECozAgrWsBgj/lxMRGMTozaWyr8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O43414	uniprotkb:Q8XAL7	intact:EBI-9679612|ensembl:ENSP00000361331.2|uniprotkb:B1AK98|uniprotkb:Q5T2T7|uniprotkb:Q5T2T9|uniprotkb:Q5TG35|uniprotkb:Q9BQA0|uniprotkb:Q9UEB4	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:eri3_human(display_long)|uniprotkb:ERI3(gene name)|psi-mi:ERI3(display_short)|uniprotkb:PINT1(gene name synonym)|uniprotkb:PRNPIP(gene name synonym)|uniprotkb:PRNPIP1(gene name synonym)|uniprotkb:Prion interactor 1(gene name synonym)|uniprotkb:Prion protein-interacting protein(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040258|imex:IM-23549-81	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000117419.16(gene)|ensembl:ENST00000372257.7(transcript)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000467""(""exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0003723""(RNA binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036397|interpro:IPR047201|interpro:IPR051274|mint:O43414|rcsb pdb:2XRI|rcsb pdb:7K05|rcsb pdb:7K06|rcsb pdb:7K07|rcsb pdb:7LPY|rcsb pdb:7LPZ|rcsb pdb:7LQ0|refseq:NP_076971.1|refseq:NP_001288627.1|refseq:NP_001288628.1|refseq:NP_001288629.1|refseq:NP_001288630.1|panther:PTHR23044(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:Ke3BT8EH5uiVr+FunIbBBwvh/bM9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:3F32436FC00C1FC6|rigid:0ZVXKihI+3/vwEnITaIrN+fXQ4E	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9H3R5	uniprotkb:Q8XB62	intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006.2	intact:EBI-10038787|uniprotkb:Q7ACX7|uniprotkb:A0A0H3JG75|uniprotkb:A0A6M0JSQ6	psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short)	psi-mi:q8xb62_eco57(display_long)|uniprotkb:espJ(gene name)|psi-mi:espJ(display_short)|uniprotkb:ECs_2714(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040223|imex:IM-23549-70	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_075060.1|ensembl:ENSG00000153044.10(gene)|ensembl:ENST00000283006.7(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000939""(inner kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007059""(chromosome segregation)|go:""GO:0043515""(kinetochore binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0051383""(kinetochore organization)|interpro:IPR008426(Centromere H)|interpro:IPR040034|mint:Q9H3R5|rcsb pdb:7PB4|rcsb pdb:7PKN|rcsb pdb:7QOO|rcsb pdb:7R5S|rcsb pdb:7R5V|rcsb pdb:7XHN|rcsb pdb:7XHO|rcsb pdb:7YWX|rcsb pdb:7YYH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|panther:PTHR48122(orthology-group)"	refseq:WP_000022458.1|interpro:IPR015226(AvrPphF ORF-2)|refseq:NP_310741.1	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606	rogid:pwnhf6VxgSKHIqJxvoUGpqp7Iu083334	intact-crc:05079D1E8EC3FB0D|rigid:E2ee4xRBiu3oDMgP8APRWAyxul4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NPQ8	uniprotkb:Q8XB62	intact:EBI-717509|uniprotkb:Q0P508|uniprotkb:Q2T9J1|uniprotkb:Q7Z352|uniprotkb:Q96EZ1|uniprotkb:Q96SZ2|uniprotkb:Q9H064|uniprotkb:Q9H5H3|uniprotkb:Q9H9E7|ensembl:ENSP00000432008.1	intact:EBI-10038787|uniprotkb:Q7ACX7|uniprotkb:A0A0H3JG75|uniprotkb:A0A6M0JSQ6	psi-mi:ric8a_human(display_long)|uniprotkb:RIC8A(gene name)|psi-mi:RIC8A(display_short)|uniprotkb:Synembryn-A(gene name synonym)	psi-mi:q8xb62_eco57(display_long)|uniprotkb:espJ(gene name)|psi-mi:espJ(display_short)|uniprotkb:ECs_2714(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040217|imex:IM-23549-68	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273063.1|refseq:NP_068751.4|refseq:XP_016873596.1|ensembl:ENSG00000177963.15(gene)|ensembl:ENST00000526104.6(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001944""(vasculature development)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0008542""(visual learning)|go:""GO:0042074""(cell migration involved in gastrulation)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0070586""(cell-cell adhesion involved in gastrulation)|go:""GO:0071711""(basement membrane organization)|interpro:IPR008376(Synembryn)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019318|mint:Q9NPQ8|panther:PTHR12425(orthology-group)"	refseq:WP_000022458.1|interpro:IPR015226(AvrPphF ORF-2)|refseq:NP_310741.1	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:jNCxRLnDY2aSw6SMtE82Tny1IE89606	rogid:pwnhf6VxgSKHIqJxvoUGpqp7Iu083334	intact-crc:6BB7A2C7FD268C6A|rigid:G9MzjwIAron9qJW3oXc71+l1qos	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P01210	uniprotkb:Q8XAJ5	intact:EBI-6656032|uniprotkb:B2RC23|uniprotkb:Q6FHC6|uniprotkb:Q6FHE6|ensembl:ENSP00000324248.3|ensembl:ENSP00000400894.2	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	psi-mi:penk_human(display_long)|uniprotkb:PENK(gene name)|psi-mi:PENK(display_short)	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040235|imex:IM-23549-74	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001129162.1|ensembl:ENSG00000181195.11(gene)|ensembl:ENST00000314922.3(transcript)|ensembl:ENST00000451791.7(transcript)|go:""GO:0001515""(opioid peptide activity)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001662""(behavioral fear response)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001964""(startle response)|go:""GO:0002118""(aggressive behavior)|go:""GO:0005184""(neuropeptide hormone activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007600""(sensory perception)|go:""GO:0009636""(response to toxic substance)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0019226""(transmission of nerve impulse)|go:""GO:0019233""(sensory perception of pain)|go:""GO:0030425""(dendrite)|go:""GO:0031628""(opioid receptor binding)|go:""GO:0032280""(symmetric synapse)|go:""GO:0032355""(response to estradiol)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0034466""(chromaffin granule lumen)|go:""GO:0034592""(synaptic vesicle lumen)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035094""(response to nicotine)|go:""GO:0035641""(locomotory exploration behavior)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0038003""(G protein-coupled opioid receptor signaling pathway)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043204""(perikaryon)|go:""GO:0043679""(axon terminus)|go:""GO:0045471""(response to ethanol)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051867""(general adaptation syndrome, behavioral process)|go:""GO:0070852""(cell body fiber)|go:""GO:0071305""(cellular response to vitamin D)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071871""(response to epinephrine)|go:""GO:0098586""(cellular response to virus)|go:""GO:0099013""(neuronal dense core vesicle lumen)|go:""GO:0099538""(synaptic signaling via neuropeptide)|go:""GO:2000987""(positive regulation of behavioral fear response)|interpro:IPR000703(Proenkephalin A)|interpro:IPR006024(Opioid neuropeptide precursor)|rcsb pdb:1PLW|rcsb pdb:1PLX|rcsb pdb:2LWC|rcsb pdb:5E33|rcsb pdb:5E3A|rcsb pdb:8JGF|rcsb pdb:8JGG|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-418594|reactome:R-HSA-8957275|panther:PTHR11438(orthology-group)"	refseq:WP_001025672.1|refseq:NP_309839.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:xL8ujOb7RFDy5+t+Oe/ph/XOoOM9606	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	intact-crc:E529E2F33965D3CE|rigid:KpaHhap6NOsiixUq12D75qNbINA	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8XA11	uniprotkb:Q96HQ2	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	intact:EBI-10038935|uniprotkb:Q8WVE3|ensembl:ENSP00000394183.2	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	psi-mi:c2ail_human(display_long)|uniprotkb:CDKN2AIPNL(gene name)|psi-mi:CDKN2AIPNL(display_short)|uniprotkb:CDKN2A-interacting protein N-terminal-like protein(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040287|imex:IM-23549-90	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	refseq:NP_542387.1|dip:DIP-61982N|ensembl:ENSG00000237190.4(gene)|ensembl:ENST00000458198.3(transcript)|interpro:IPR021859|mint:Q96HQ2	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/12/22	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	rogid:D9Y5uROpQokbORFnDCrBSgHRTHc9606	intact-crc:B024070FF0E77D09|rigid:7/P51M3xeh+kbvOIp9l87t6D/nc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8XB62	uniprotkb:Q96HT8	intact:EBI-10038787|uniprotkb:Q7ACX7|uniprotkb:A0A0H3JG75|uniprotkb:A0A6M0JSQ6	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154.6	psi-mi:q8xb62_eco57(display_long)|uniprotkb:espJ(gene name)|psi-mi:espJ(display_short)|uniprotkb:ECs_2714(orf name)	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040220|imex:IM-23549-69	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000022458.1|interpro:IPR015226(AvrPphF ORF-2)|refseq:NP_310741.1	"refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988.11(gene)|ensembl:ENST00000320848.7(transcript)|go:""GO:0042802""(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|panther:PTHR31324(orthology-group)"	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/10	rogid:pwnhf6VxgSKHIqJxvoUGpqp7Iu083334	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	intact-crc:7C21A1CA6FFA3C10|rigid:B4DOPbQLC1N4Bvf5sgdEq9FpAVo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P62191	uniprotkb:Q8XA11	intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|uniprotkb:Q6NW36|uniprotkb:B4DR63|ensembl:ENSP00000261303.8	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym)	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040275|imex:IM-23549-86	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002793.2|ensembl:ENSG00000100764.14(gene)|ensembl:ENST00000261303.13(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|refseq:NP_001317141.1|refseq:XP_016876959.1|panther:PTHR23073(orthology-group)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	intact-crc:28FD8A3BC205F4DB|rigid:BQnzh2juILO/0YE9dI5RQvjokTc	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96IZ6	uniprotkb:A0A0H3JGR6	intact:EBI-7211882|uniprotkb:A6NNC4|uniprotkb:Q9P0B5|uniprotkb:Q9H9G9|uniprotkb:Q9NUI8|intact:MINT-3054259|ensembl:ENSP00000309610.6	intact:EBI-10039274|uniprotkb:A0A7U8R338|uniprotkb:A0A6M0JIH9|uniprotkb:A0A6M7CAZ4	psi-mi:met2a_human(display_long)|uniprotkb:METTL2A(gene name)|psi-mi:METTL2A(display_short)|uniprotkb:METTL2(gene name synonym)|uniprotkb:Methyltransferase-like protein 2A(gene name synonym)|uniprotkb:HSPC266(orf name)	psi-mi:a0a0h3jgr6_eco57(display_long)|uniprotkb:nleD(gene name)|psi-mi:nleD(display_short)|uniprotkb:ECs_0850(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040249|imex:IM-23549-78	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_859076.3|ensembl:ENSG00000087995.16(gene)|ensembl:ENST00000311506.10(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0006399""(tRNA metabolic process)|go:""GO:0006400""(tRNA modification)|go:""GO:0030488""(tRNA methylation)|go:""GO:0052735""(""tRNA (cytidine-3-)-methyltransferase activity"")|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR026113|interpro:IPR029063|mint:Q96IZ6|panther:PTHR22809(orthology-group)"	uniprotkb:Q7AGE0(uniprot-removed-ac)|refseq:WP_001247925.1|interpro:IPR028208|refseq:NP_308877.1	-	comment:mint|function:Probable methyltransferase|comment:homomint	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:UDMjkoiVoFtAUI7N3PDqj5ELSFI9606	rogid:zkF+5p88ddmXoI6VON0GRkdetcU83334	intact-crc:6E79097884A90B6C|rigid:mLvQ55YwmTtroKvdTxrjyulJLrQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P61968	uniprotkb:Q8XAL7	intact:EBI-2798728|uniprotkb:O00158|uniprotkb:O88894|ensembl:ENSP00000359573.1|ensembl:ENSP00000359575.4|uniprotkb:D3DT23	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:lmo4_human(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:LMO4(gene name)|psi-mi:LMO4(display_short)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040261|imex:IM-23549-82	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006760.1|ensembl:ENSG00000143013.13(gene)|ensembl:ENST00000370542.1(transcript)|ensembl:ENST00000370544.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001843""(neural tube closure)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0021514""(ventral spinal cord interneuron differentiation)|go:""GO:0021520""(spinal cord motor neuron cell fate specification)|go:""GO:0021527""(spinal cord association neuron differentiation)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0031252""(cell leading edge)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0042659""(regulation of cell fate specification)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048538""(thymus development)|go:""GO:0050865""(regulation of cell activation)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR050945|mint:P61968|rcsb pdb:9F5B|refseq:XP_005271348.1|dip:DIP-41414N|panther:PTHR45787(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	crc64:C8AC295144AD7787	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/24	rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:5FB448CD572BF2F3|rigid:j6OcLTceI60gI9OtnstDrWiBRvw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8XAJ5	uniprotkb:P56555	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	intact:EBI-10039117|uniprotkb:Q4VB31	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	psi-mi:dscr4_human(display_long)|uniprotkb:DSCR4(gene name)|psi-mi:DSCR4(display_short)|uniprotkb:DCRB(gene name synonym)|uniprotkb:DSCRB(gene name synonym)|uniprotkb:Down syndrome critical region protein B(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040229|imex:IM-23549-72	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001025672.1|refseq:NP_309839.1	refseq:NP_005858.1	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	rogid:ObILr2wYLN3Wg8advbNI6ZaAta89606	intact-crc:4831A00F7210087A|rigid:FcSGEjJGaaly873gwKO+F9MXyfs	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8XAL7	uniprotkb:P00374	intact:EBI-10039292|uniprotkb:Q7AEM9	intact:EBI-10039315|uniprotkb:B4DDD2|uniprotkb:Q14130|uniprotkb:Q6IRW8|ensembl:ENSP00000396308.2|ensembl:ENSP00000426474.1	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	psi-mi:dyr_human(display_long)|uniprotkb:DHFR(gene name)|psi-mi:DHFR(display_short)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040255|imex:IM-23549-80	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	"rcsb pdb:2W3A|ensembl:ENSG00000228716.7(gene)|ensembl:ENST00000439211.7(transcript)|ensembl:ENST00000505337.5(transcript)|go:""GO:0000900""(mRNA regulatory element binding translation repressor activity)|go:""GO:0003729""(mRNA binding)|go:""GO:0004146""(dihydrofolate reductase activity)|go:""GO:0005542""(folic acid binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006729""(tetrahydrobiopterin biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031103""(axon regeneration)|go:""GO:0031427""(response to methotrexate)|go:""GO:0046452""(dihydrofolate metabolic process)|go:""GO:0046653""(tetrahydrofolate metabolic process)|go:""GO:0046654""(tetrahydrofolate biosynthetic process)|go:""GO:0046655""(folic acid metabolic process)|go:""GO:0050661""(NADP binding)|go:""GO:0051000""(positive regulation of nitric-oxide synthase activity)|go:""GO:0070402""(NADPH binding)|go:""GO:1990825""(sequence-specific mRNA binding)|go:""GO:2000121""(regulation of removal of superoxide radicals)|interpro:IPR001796(Dihydrofolate reductase region)|interpro:IPR012259(Dihydrofolate reductase)|interpro:IPR017925|interpro:IPR024072|rcsb pdb:2W3B|mint:P00374|rcsb pdb:1BOZ|rcsb pdb:1DHF|rcsb pdb:1DLR|rcsb pdb:1DLS|rcsb pdb:1DRF|rcsb pdb:1HFP|rcsb pdb:1HFQ|rcsb pdb:1HFR|rcsb pdb:1KMS|rcsb pdb:1KMV|rcsb pdb:1MVS|rcsb pdb:1MVT|rcsb pdb:1OHJ|rcsb pdb:1OHK|rcsb pdb:1PD8|rcsb pdb:1PD9|rcsb pdb:1PDB|rcsb pdb:1S3U|rcsb pdb:1S3V|rcsb pdb:1S3W|rcsb pdb:1U71|rcsb pdb:1U72|rcsb pdb:1YHO|rcsb pdb:2C2S|rcsb pdb:2C2T|rcsb pdb:2DHF|rcsb pdb:2W3M|rcsb pdb:3EIG|rcsb pdb:3F8Y|rcsb pdb:3F8Z|rcsb pdb:3F91|rcsb pdb:3FS6|rcsb pdb:3GHC|rcsb pdb:3GHV|rcsb pdb:3GHW|rcsb pdb:3GI2|rcsb pdb:3GYF|rcsb pdb:3L3R|rcsb pdb:3N0H|rcsb pdb:3NTZ|rcsb pdb:3NU0|rcsb pdb:3NXO|rcsb pdb:3NXR|rcsb pdb:3NXT|rcsb pdb:3NXV|rcsb pdb:3NXX|rcsb pdb:3NXY|rcsb pdb:3NZD|rcsb pdb:3OAF|rcsb pdb:3S3V|rcsb pdb:3S7A|rcsb pdb:4DDR|rcsb pdb:4G95|rcsb pdb:4KAK|rcsb pdb:4KBN|rcsb pdb:4KD7|rcsb pdb:4KEB|rcsb pdb:4KFJ|rcsb pdb:4M6J|rcsb pdb:4M6K|rcsb pdb:4M6L|rcsb pdb:4QHV|rcsb pdb:4QJC|rcsb pdb:5HPB|rcsb pdb:5HQY|rcsb pdb:5HQZ|rcsb pdb:5HSR|rcsb pdb:5HSU|rcsb pdb:5HT4|rcsb pdb:5HT5|rcsb pdb:5HUI|rcsb pdb:5HVB|rcsb pdb:5HVE|rcsb pdb:5SD6|rcsb pdb:5SD7|rcsb pdb:5SD8|rcsb pdb:5SD9|rcsb pdb:5SDA|rcsb pdb:5SDB|rcsb pdb:6A7C|rcsb pdb:6A7E|rcsb pdb:6DAV|rcsb pdb:6DE4|rcsb pdb:6VCJ|rcsb pdb:7ESE|rcsb pdb:7XI7|rcsb pdb:8WGN|reactome:R-HSA-1474151|reactome:R-HSA-196757|reactome:R-HSA-69205|refseq:NP_000782.1|refseq:NP_001277283.1|panther:PTHR48069(orthology-group)|efo:""Orphanet:319651"""	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	rogid:4yoitO/ETpazAN2OtD/rXCte4289606	intact-crc:CFF7AFB8EB3C6C90|rigid:BwRxu/G90K7THotPE+clPdJgMdQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7DB85	uniprotkb:Q9UI95	intact:EBI-10038700|uniprotkb:Q7A9R0|uniprotkb:A0A0H3JQD8	intact:EBI-77889|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3|ensembl:ENSP00000235310.2|ensembl:ENSP00000365855.3|ensembl:ENSP00000365882.4|ensembl:ENSP00000400982.2	psi-mi:q7db85_eco57(display_long)|uniprotkb:espF(gene name)|psi-mi:espF(display_short)|uniprotkb:ECs_4550(orf name)	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040201|imex:IM-23549-64	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006891(EspF protein)|refseq:WP_000931693.1|refseq:NP_312577.1	"panther:PTHR11842(orthology-group)|efo:""Orphanet:84""|ensembl:ENSG00000116670.17(gene)|ensembl:ENST00000235310.7(transcript)|ensembl:ENST00000376667.7(transcript)|ensembl:ENST00000376692.9(transcript)|ensembl:ENST00000456915.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002208""(somatic diversification of immunoglobulins involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006302""(double-strand break repair)|go:""GO:0007015""(actin filament organization)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|rcsb pdb:6WS0|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016035""(zeta DNA polymerase complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0042772""(DNA damage response, signal transduction resulting in transcription)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051301""(cell division)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000678""(negative regulation of transcription regulatory region DNA binding)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|interpro:IPR045091|mint:Q9UI95|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/06	rogid:Xi+lGjtCtERpBpNdPvEPyVtkQlA83334	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	intact-crc:94EF35971035A4E3|rigid:mo1NSwnqmsBgvMW9SA+QggPUKSg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P61601	uniprotkb:Q7DB77	intact:EBI-749635|uniprotkb:P29554|uniprotkb:Q8IYC3|uniprotkb:Q9H0W2|ensembl:ENSP00000220931.6|ensembl:ENSP00000310587.3|ensembl:ENSP00000379256.1|ensembl:ENSP00000428105.1|ensembl:ENSP00000430476.1	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:ncald_human(display_long)|uniprotkb:NCALD(gene name)|psi-mi:NCALD(display_short)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040313|imex:IM-23549-92	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035714.1|refseq:NP_001035715.1|refseq:NP_001035716.1|refseq:NP_001035717.1|refseq:NP_001035718.1|refseq:NP_001035719.1|refseq:NP_001035720.1|refseq:NP_114430.2|ensembl:ENSG00000104490.18(gene)|ensembl:ENST00000220931.11(transcript)|ensembl:ENST00000311028.4(transcript)|ensembl:ENST00000395923.5(transcript)|ensembl:ENST00000519508.6(transcript)|ensembl:ENST00000521599.5(transcript)|go:""GO:0003073""(regulation of systemic arterial blood pressure)|go:""GO:0003779""(actin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0015631""(tubulin binding)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0030130""(clathrin coat of trans-Golgi network vesicle)|go:""GO:0030276""(clathrin binding)|go:""GO:0043014""(alpha-tubulin binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:P61601|reactome:R-HSA-451308|refseq:XP_011515634.1|refseq:XP_011515635.1|refseq:XP_011515636.1|refseq:XP_011515637.1|refseq:XP_016869390.1|refseq:XP_016869391.1|panther:PTHR23055(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:1/KBd+bN0cMZa81XKSSGPxgQEzc9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:937E4515767C44E6|rigid:NW9lpVQdfwALyaamEljTN/cqgoo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P61601	uniprotkb:B7UM99	intact:EBI-749635|uniprotkb:P29554|uniprotkb:Q8IYC3|uniprotkb:Q9H0W2|ensembl:ENSP00000220931.6|ensembl:ENSP00000310587.3|ensembl:ENSP00000379256.1|ensembl:ENSP00000428105.1|ensembl:ENSP00000430476.1	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:ncald_human(display_long)|uniprotkb:NCALD(gene name)|psi-mi:NCALD(display_short)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040320|imex:IM-23549-93	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035714.1|refseq:NP_001035715.1|refseq:NP_001035716.1|refseq:NP_001035717.1|refseq:NP_001035718.1|refseq:NP_001035719.1|refseq:NP_001035720.1|refseq:NP_114430.2|ensembl:ENSG00000104490.18(gene)|ensembl:ENST00000220931.11(transcript)|ensembl:ENST00000311028.4(transcript)|ensembl:ENST00000395923.5(transcript)|ensembl:ENST00000519508.6(transcript)|ensembl:ENST00000521599.5(transcript)|go:""GO:0003073""(regulation of systemic arterial blood pressure)|go:""GO:0003779""(actin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0015631""(tubulin binding)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0030130""(clathrin coat of trans-Golgi network vesicle)|go:""GO:0030276""(clathrin binding)|go:""GO:0043014""(alpha-tubulin binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:P61601|reactome:R-HSA-451308|refseq:XP_011515634.1|refseq:XP_011515635.1|refseq:XP_011515636.1|refseq:XP_011515637.1|refseq:XP_016869390.1|refseq:XP_016869391.1|panther:PTHR23055(orthology-group)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:1/KBd+bN0cMZa81XKSSGPxgQEzc9606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:904D1D25AE0F1928|rigid:KOkLD6ohI0DfNhDddALFgKV+UJs	false	-	sufficient binding region:1-267(IPR022633)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8XA11	uniprotkb:Q6Y2X3	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	intact:EBI-10038974|uniprotkb:A5YM67|uniprotkb:Q17RY2|uniprotkb:Q66K17|uniprotkb:Q96N59|uniprotkb:Q96T63|ensembl:ENSP00000317500.5|ensembl:ENSP00000350223.3|ensembl:ENSP00000448876.2|ensembl:ENSP00000450196.2|ensembl:ENSP00000504134.1	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	psi-mi:djc14_human(display_long)|uniprotkb:DNAJC14(gene name)|psi-mi:DNAJC14(display_short)|uniprotkb:DRIP78(gene name synonym)|uniprotkb:HDJ3(gene name synonym)|uniprotkb:DnaJ protein homolog 3(gene name synonym)|uniprotkb:Dopamine receptor-interacting protein of 78 kDa(gene name synonym)|uniprotkb:Human DnaJ protein 3(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040281|imex:IM-23549-88	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	"refseq:NP_115740.5|ensembl:ENSG00000135392.19(gene)|ensembl:ENST00000317287.5(transcript)|ensembl:ENST00000357606.7(transcript)|ensembl:ENST00000546957.2(transcript)|ensembl:ENST00000547445.2(transcript)|ensembl:ENST00000678005.2(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0050780""(dopamine receptor binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR032843|interpro:IPR036869|interpro:IPR052317|mint:Q6Y2X3|panther:PTHR44665(orthology-group)"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	rogid:oS3c968UKq0i0JRZxUJFskA5HD89606	intact-crc:12C96DD546CF526C|rigid:zrdoJVyFVTprLL5aBAyHrVWpLOk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8XBX8	uniprotkb:P19388	intact:EBI-10039153|uniprotkb:Q7AAV0|uniprotkb:A0A0H3JHS6|uniprotkb:A0A6M0JF43	intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739.1|ensembl:ENSP00000478303.1|ensembl:ENSP00000485021.1	psi-mi:nleb1_eco57(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:ECs3857(locus name)	psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040243|imex:IM-23549-76	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000953022.1|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|refseq:NP_311884.1"	"refseq:NP_002686.2|ensembl:ENSG00000099817.12(gene)|ensembl:ENST00000586746.5(transcript)|ensembl:ENST00000612655.4(transcript)|ensembl:ENST00000615234.5(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005665""(RNA polymerase II, core complex)|go:""GO:0005666""(RNA polymerase III complex)|go:""GO:0005736""(RNA polymerase I complex)|go:""GO:0005829""(cytosol)|go:""GO:0006362""(transcription elongation by RNA polymerase I)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0042797""(tRNA transcription by RNA polymerase III)|go:""GO:0050821""(protein stabilization)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR035913|interpro:IPR036710|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7FJI|rcsb pdb:7FJJ|rcsb pdb:7LBM|rcsb pdb:7OB9|rcsb pdb:7OBA|rcsb pdb:7OBB|rcsb pdb:7VBA|rcsb pdb:7VBB|rcsb pdb:7VBC|rcsb pdb:8A43|rcsb pdb:8ITY|rcsb pdb:8IUE|rcsb pdb:8IUH|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-56N|panther:PTHR10535(orthology-group)"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/03/27	rogid:s08ivrjNoMdHHNcIwH+V7ZobNOQ83334	rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606	intact-crc:3CA1D2E1DAB17CD3|rigid:EGGLTS8gvnQ9KWaTXgG0OZXT9ZM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9NWS0	uniprotkb:Q8XA11	intact:EBI-357318|intact:EBI-748162|uniprotkb:B4DGN7|uniprotkb:B4E2X7|uniprotkb:Q9BVL0|ensembl:ENSP00000262265.4|ensembl:ENSP00000470445.1	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	psi-mi:pihd1_human(display_long)|uniprotkb:PIH1D1(gene name)|psi-mi:PIH1D1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17 homolog(gene name synonym)	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040278|imex:IM-23549-87	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060386.1|ensembl:ENSG00000104872.12(gene)|ensembl:ENST00000262265.10(transcript)|ensembl:ENST00000596049.5(transcript)|go:""GO:0000492""(box C/D snoRNP assembly)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006364""(rRNA processing)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0042393""(histone binding)|go:""GO:0048254""(snoRNA localization)|go:""GO:0050821""(protein stabilization)|go:""GO:0051117""(ATPase binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0070761""(pre-snoRNP complex)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097255""(R2TP complex)|go:""GO:0140566""(histone reader activity)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1902661""(positive regulation of glucose mediated signaling pathway)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1905669""(TORC1 complex assembly)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR012981(Nop17p)|interpro:IPR041442|interpro:IPR050734|mint:Q9NWS0|rcsb pdb:4PSF|rcsb pdb:4PSI|rcsb pdb:6GXZ|rcsb pdb:7AVC|rcsb pdb:8BDU|panther:PTHR22997(orthology-group)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:lugKS0BlzZYpMZn/7LFHODnFk0Q9606	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	intact-crc:901B85C29CA1DD13|rigid:BOQdiS8j1wlzSuTh62U6lJGzrzo	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TCX5	uniprotkb:Q7DB76	intact:EBI-746325|ensembl:ENSP00000289013.6|uniprotkb:Q8TAV1|uniprotkb:Q96PV9|intact:EBI-12011872	intact:EBI-10039068|uniprotkb:Q7A9Q0|uniprotkb:A0A0H3JJD5|uniprotkb:A0A6M0JL37	psi-mi:rhpn1_human(display_long)|uniprotkb:KIAA1929(gene name synonym)|uniprotkb:GTP-Rho-binding protein 1(gene name synonym)|uniprotkb:RHPN1(gene name)|psi-mi:RHPN1(display_short)	psi-mi:q7db76_eco57(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:ECs_4562(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040226|imex:IM-23549-71	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000158106.15(gene)|ensembl:ENST00000289013.11(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0051497""(negative regulation of stress fiber assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004328(BRO1)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR036034|interpro:IPR036274|interpro:IPR038499|interpro:IPR042715|interpro:IPR047138|mint:Q8TCX5|reactome:R-HSA-5666185|reactome:R-HSA-8980692|refseq:NP_443156.2|panther:PTHR23031(orthology-group)"	refseq:WP_000492638.1|interpro:IPR004959(IpaB/EvcA)|refseq:NP_312589.1	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:EF1IVH0DLg/1KL4iWFVBktsl5589606	rogid:xO5ymWP2ug1VLyxelIaeen+24gM83334	intact-crc:C3E13F7AFD7DA191|rigid:0Yiwj0imHykFHVs92LsiUMA6cao	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7DB77	uniprotkb:O43924	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600.4	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040019|imex:IM-23549-60	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"ensembl:ENSG00000156973.14(gene)|ensembl:ENST00000287600.9(transcript)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005929""(cilium)|go:""GO:0007601""(visual perception)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|rcsb pdb:7PAC|rcsb pdb:7PAD|rcsb pdb:7PAE|rcsb pdb:7Q9Q|rcsb pdb:7Q9R|rcsb pdb:7Q9S|rcsb pdb:7Q9U|rcsb pdb:7QF9|rcsb pdb:7QJK|reactome:R-HSA-5624958|reactome:R-HSA-9648002|refseq:NP_001277947.1|refseq:NP_002592.1|efo:""Orphanet:2754""|efo:""Orphanet:475""|dip:DIP-36660N|panther:PTHR12976(orthology-group)"	-	-	-	figure legend:Fig. 5B|comment:Interaction appears to be very weak.|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	intact-crc:621809A7E55596B4|rigid:nSx3EzGVFU/94uLHaqDzzak+8G8	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BYM8	uniprotkb:Q8XC86	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632.6	intact:EBI-10038594|uniprotkb:Q7A9Q6|uniprotkb:A0A0H3JJC8|uniprotkb:A0A6M0JLD0	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:q8xc86_eco57(display_long)|uniprotkb:espB(gene name)|psi-mi:espB(display_short)|uniprotkb:ECs_4554(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040186|imex:IM-23549-63	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-47737N|ensembl:ENSG00000125826.22(gene)|ensembl:ENST00000356286.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0071797""(LUBAC complex)|go:""GO:0097039""(protein linear polyubiquitination)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1990757""(ubiquitin ligase activator activity)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|interpro:IPR047557|interpro:IPR047558|interpro:IPR047559|interpro:IPR051628|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|rcsb pdb:7V8E|rcsb pdb:7YUI|rcsb pdb:7YUJ|rcsb pdb:8BVL|rcsb pdb:8EAZ|rcsb pdb:8K6Q|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|refseq:NP_006453.1|refseq:NP_112506.2|efo:""Orphanet:329173""|efo:""Orphanet:397937""|panther:PTHR22770(orthology-group)"	refseq:WP_001092000.1|interpro:IPR008611(Enterobacterial EspB)|refseq:NP_312581.1	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/03/26	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	rogid:9cKWrLKb1089HnklaM95O3OLdTQ83334	intact-crc:8C052226E119889C|rigid:Cr3FpGA3wpV+Ewb6qFIbZAB7y2g	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7DB77	uniprotkb:O75716	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964.2|ensembl:ENSP00000386928.3	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040025|imex:IM-23549-61	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_001008910.1|ensembl:ENSG00000115661.14(gene)|ensembl:ENST00000396738.7(transcript)|ensembl:ENST00000409638.7(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR052239|mint:O75716|rcsb pdb:2BUJ|refseq:NP_001317142.1|dip:DIP-29598N|panther:PTHR45998(orthology-group)"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/24	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606	intact-crc:B9E41E7FF6C922AB|rigid:PtFZg2M0P8t6pPCwD5zeyLdixIc	false	sufficient binding region:333-558(IPR022639)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O75716	uniprotkb:B7UM99	intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964.2|ensembl:ENSP00000386928.3	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040304|imex:IM-23549-91	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001008910.1|ensembl:ENSG00000115661.14(gene)|ensembl:ENST00000396738.7(transcript)|ensembl:ENST00000409638.7(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR052239|mint:O75716|rcsb pdb:2BUJ|refseq:NP_001317142.1|dip:DIP-29598N|panther:PTHR45998(orthology-group)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/24	rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:0451BBE467B9C944|rigid:lMWC0234Z1g7aKWhVEk5UZffGQw	false	-	sufficient binding region:338-550(IPR022639)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96Q11	uniprotkb:Q8XAL7	intact:EBI-2839106|uniprotkb:Q9Y362|uniprotkb:Q9BS97|uniprotkb:Q8ND57|uniprotkb:A8K2Z6|uniprotkb:B7WP13|uniprotkb:C9JKA2|ensembl:ENSP00000251607.6|ensembl:ENSP00000415100.1|ensembl:ENSP00000513700.1|ensembl:ENSP00000513701.1|ensembl:ENSP00000513705.1	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:trnt1_human(display_long)|uniprotkb:TRNT1(gene name)|psi-mi:TRNT1(display_short)|uniprotkb:Mitochondrial tRNA nucleotidyl transferase, CCA-adding(gene name synonym)|uniprotkb:mt CCA-adding enzyme(gene name synonym)|uniprotkb:mt tRNA CCA-diphosphorylase(gene name synonym)|uniprotkb:mt tRNA CCA-pyrophosphorylase(gene name synonym)|uniprotkb:mt tRNA adenylyltransferase(gene name synonym)|uniprotkb:CGI-47(orf name)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040265|imex:IM-23549-83	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:369861""|ensembl:ENSG00000072756.18(gene)|ensembl:ENST00000251607.11(transcript)|ensembl:ENST00000434583.5(transcript)|ensembl:ENST00000698406.1(transcript)|ensembl:ENST00000698408.1(transcript)|ensembl:ENST00000698412.1(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0001680""(tRNA 3'-terminal CCA addition)|go:""GO:0004810""(CCA tRNA nucleotidyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0034062""(5'-3' RNA polymerase activity)|go:""GO:0042780""(tRNA 3'-end processing)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0106354""(tRNA surveillance)|go:""GO:0160016""(CCACCA tRNA nucleotidyltransferase activity)|go:""GO:1990180""(mitochondrial tRNA 3'-end processing)|interpro:IPR002646(Polynucleotide adenylyltransferase region)|interpro:IPR032828|interpro:IPR043519|interpro:IPR050264|rcsb pdb:1OU5|rcsb pdb:4X4W|rcsb pdb:8CBM|reactome:R-HSA-6784531|reactome:R-HSA-6785470|refseq:NP_001289875.1|refseq:NP_886552.2|refseq:XP_011532078.1|refseq:XP_011532079.1|refseq:XP_011532080.1|panther:PTHR46173(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:COxi4PrWifNnDPkI+lile/5kD9I9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:C8A0DD10951649F9|rigid:2fkFc3ICDs1nvcYYs5P7hqnjtmI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P49759	uniprotkb:Q8XA11	intact:EBI-473775|uniprotkb:Q8N5V8|uniprotkb:Q0P694|intact:EBI-2622912|uniprotkb:B4DFW7|ensembl:ENSP00000326830.4	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	psi-mi:clk1_human(display_long)|uniprotkb:CDC-like kinase 1(gene name synonym)|uniprotkb:CLK1(gene name)|psi-mi:CLK1(display_short)|uniprotkb:CLK(gene name synonym)	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040284|imex:IM-23549-89	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004062.2|refseq:NP_001155879.1|panther:PTHR45646(orthology-group)|rcsb pdb:6R6E|ensembl:ENSG00000013441.17(gene)|ensembl:ENST00000321356.9(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004712""(protein serine/threonine/tyrosine kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR051175|mint:P49759|rcsb pdb:1Z57|rcsb pdb:2VAG|rcsb pdb:5J1V|rcsb pdb:5J1W|rcsb pdb:5X8I|rcsb pdb:6FT8|rcsb pdb:6FT9|rcsb pdb:6FYO|rcsb pdb:6G33|rcsb pdb:6I5H|rcsb pdb:6I5I|rcsb pdb:6I5K|rcsb pdb:6I5L|rcsb pdb:6KHD|rcsb pdb:6Q8K|rcsb pdb:6Q8P|rcsb pdb:6QTY|rcsb pdb:6R3D|rcsb pdb:6R6X|rcsb pdb:6R8J|rcsb pdb:6RAA|rcsb pdb:6TW2|rcsb pdb:6YTA|rcsb pdb:6YTD|rcsb pdb:6YTE|rcsb pdb:6YTG|rcsb pdb:6YTI|rcsb pdb:6Z4Z|rcsb pdb:6Z50|rcsb pdb:6ZLN|rcsb pdb:7AK3|rcsb pdb:7O9Y|rcsb pdb:7OA0|rcsb pdb:7OPG|rcsb pdb:8P04|rcsb pdb:8P08"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:HUyYLfLTfZHyTdtTNdbR/HPBloM9606	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	intact-crc:B7F44E8A6D4F2766|rigid:V+VYmyTEy8pcXOEJ4ODb1NiW6cY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7DB77	uniprotkb:Q9UM19	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-744820|uniprotkb:Q5TG97|uniprotkb:Q8N611|uniprotkb:B2R5U2|uniprotkb:D3DPU1|ensembl:ENSP00000361935.3|ensembl:ENSP00000481834.1	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:hpcl4_human(display_long)|uniprotkb:HPCAL4(gene name)|psi-mi:HPCAL4(display_short)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040006|imex:IM-23549-59	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_057341.1|refseq:NP_001269325.1|refseq:XP_016856936.1|ensembl:ENSG00000116983.13(gene)|ensembl:ENST00000372844.8(transcript)|ensembl:ENST00000617690.2(transcript)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0007417""(central nervous system development)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0019904""(protein domain specific binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:Q9UM19|panther:PTHR23055(orthology-group)"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:+2KFQ7WO9Kyn14ySKaEmm1V6pRM9606	intact-crc:D88FCA03E0A3036E|rigid:1IogbQyoEvXFZXTvTXzoGXPvL0A	false	sufficient binding region:1-270(IPR022633)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P55211	uniprotkb:Q8XAL7	intact:EBI-516799|uniprotkb:O95348|uniprotkb:Q92852|uniprotkb:Q9BQ62|uniprotkb:Q9UEQ3|uniprotkb:Q9UIJ8|uniprotkb:Q53Y70|uniprotkb:Q5JRU9|uniprotkb:Q5UGI1|uniprotkb:B4E1A3|ensembl:ENSP00000330237.5	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:casp9_human(display_long)|uniprotkb:ICE-like apoptotic protease 6(gene name synonym)|uniprotkb:Apoptotic protease Mch-6(gene name synonym)|uniprotkb:Apoptotic protease-activating factor 3(gene name synonym)|uniprotkb:CASP9(gene name)|psi-mi:CASP9(display_short)|uniprotkb:MCH6(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040252|imex:IM-23549-79	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001264983.1|refseq:NP_001220.2|refseq:NP_127463.2|refseq:XP_005246071.1|ensembl:ENSG00000132906.18(gene)|ensembl:ENST00000333868.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001822""(kidney development)|go:""GO:0002931""(response to ischemia)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008233""(peptidase activity)|go:""GO:0008303""(caspase complex)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0016485""(protein processing)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030220""(platelet formation)|go:""GO:0032025""(response to cobalt ion)|go:""GO:0032355""(response to estradiol)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034349""(glial cell apoptotic process)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043293""(apoptosome)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044346""(fibroblast apoptotic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051604""(protein maturation)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0071887""(leukocyte apoptotic process)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR011600(Peptidase C14, caspase catalytic)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR042147|mint:P55211|rcsb pdb:1JXQ|rcsb pdb:1NW9|rcsb pdb:2AR9|rcsb pdb:3D9T|rcsb pdb:3V3K|rcsb pdb:3YGS|rcsb pdb:4RHW|rcsb pdb:5JUY|rcsb pdb:5WVC|rcsb pdb:5WVE|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-168638|reactome:R-HSA-198323|reactome:R-HSA-418889|reactome:R-HSA-5674400|reactome:R-HSA-9627069|panther:PTHR10454(orthology-group)|dip:DIP-27625N"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:IYW59Vh17AEnXa6/wLpkIPNE0Bo9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:CDF56805F66D139D|rigid:7k9kmTQrmSBvIMvcleDJFlJsRMU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P37235	uniprotkb:B7UM99	intact:EBI-749311|uniprotkb:Q969S5|ensembl:ENSP00000310749.3|ensembl:ENSP00000371184.3|ensembl:ENSP00000478231.1|ensembl:ENSP00000482993.1|ensembl:ENSP00000483786.1	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:hpcl1_human(display_long)|uniprotkb:Visinin-like protein 3(gene name synonym)|uniprotkb:Calcium-binding protein BDR-1(gene name synonym)|uniprotkb:HLP2(gene name synonym)|uniprotkb:HPCAL1(gene name)|psi-mi:HPCAL1(display_short)|uniprotkb:BDR1(gene name synonym)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040327|imex:IM-23549-94	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002140.2|refseq:NP_602293.1|refseq:NP_001245286.1|refseq:NP_001245287.1|refseq:NP_001245288.1|refseq:XP_005246217.1|refseq:XP_005246218.1|refseq:XP_005246219.1|refseq:XP_005246220.1|refseq:XP_016859439.1|ensembl:ENSG00000115756.13(gene)|ensembl:ENST00000307845.8(transcript)|ensembl:ENST00000381765.7(transcript)|ensembl:ENST00000613496.4(transcript)|ensembl:ENST00000620771.4(transcript)|ensembl:ENST00000622018.4(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:P37235|rcsb pdb:5T7C|refseq:XP_011508648.1|refseq:XP_011508649.1|refseq:XP_011508650.1|refseq:XP_016859440.1|refseq:XP_016859441.1|refseq:XP_016859442.1|panther:PTHR23055(orthology-group)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:oK04sIDCtghEOWIBNQ75bR34+2o9606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:8094422FE4A852DD|rigid:yE+ULWWGVJZhw2FL6KewnrcBWbw	false	-	sufficient binding region:1-270(IPR022633)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P37235	uniprotkb:Q7DB77	intact:EBI-749311|uniprotkb:Q969S5|ensembl:ENSP00000310749.3|ensembl:ENSP00000371184.3|ensembl:ENSP00000478231.1|ensembl:ENSP00000482993.1|ensembl:ENSP00000483786.1	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:hpcl1_human(display_long)|uniprotkb:Visinin-like protein 3(gene name synonym)|uniprotkb:Calcium-binding protein BDR-1(gene name synonym)|uniprotkb:HLP2(gene name synonym)|uniprotkb:HPCAL1(gene name)|psi-mi:HPCAL1(display_short)|uniprotkb:BDR1(gene name synonym)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039998|imex:IM-23549-58	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002140.2|refseq:NP_602293.1|refseq:NP_001245286.1|refseq:NP_001245287.1|refseq:NP_001245288.1|refseq:XP_005246217.1|refseq:XP_005246218.1|refseq:XP_005246219.1|refseq:XP_005246220.1|refseq:XP_016859439.1|ensembl:ENSG00000115756.13(gene)|ensembl:ENST00000307845.8(transcript)|ensembl:ENST00000381765.7(transcript)|ensembl:ENST00000613496.4(transcript)|ensembl:ENST00000620771.4(transcript)|ensembl:ENST00000622018.4(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:P37235|rcsb pdb:5T7C|refseq:XP_011508648.1|refseq:XP_011508649.1|refseq:XP_011508650.1|refseq:XP_016859440.1|refseq:XP_016859441.1|refseq:XP_016859442.1|panther:PTHR23055(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:oK04sIDCtghEOWIBNQ75bR34+2o9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:6DFDDC1E1E92BE81|rigid:1cwDS9Ro06Jrm9ll7Abp4YUxFYM	false	-	sufficient binding region:1-270(IPR022633)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P55039	uniprotkb:Q8XBX8	intact:EBI-750565|uniprotkb:Q9BWB2|uniprotkb:B2R8G5|uniprotkb:Q53Y50|ensembl:ENSP00000225729.3	intact:EBI-10039153|uniprotkb:Q7AAV0|uniprotkb:A0A0H3JHS6|uniprotkb:A0A6M0JF43	psi-mi:drg2_human(display_long)|uniprotkb:DRG2(gene name)|psi-mi:DRG2(display_short)|uniprotkb:Translation factor GTPase DRG2(gene name synonym)	psi-mi:nleb1_eco57(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:ECs3857(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040246|imex:IM-23549-77	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001379.1|ensembl:ENSG00000108591.10(gene)|ensembl:ENST00000225729.8(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|interpro:IPR045001|reactome:R-HSA-9629569|panther:PTHR43127(orthology-group)"	"refseq:WP_000953022.1|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|refseq:NP_311884.1"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:9bgX8C0kJmO5KdaYHU+vAmDCTPo9606	rogid:s08ivrjNoMdHHNcIwH+V7ZobNOQ83334	intact-crc:148533115B390B3C|rigid:dD+KM+yBSkP8/jr7kNRM9Vf95Rw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7DB85	uniprotkb:Q8WV41	intact:EBI-10038700|uniprotkb:Q7A9R0|uniprotkb:A0A0H3JQD8	intact:EBI-2481535|uniprotkb:B1NM17|ensembl:ENSP00000311427.6	psi-mi:q7db85_eco57(display_long)|uniprotkb:espF(gene name)|psi-mi:espF(display_short)|uniprotkb:ECs_4550(orf name)	psi-mi:snx33_human(display_long)|uniprotkb:SNX33(gene name)|psi-mi:SNX33(display_short)|uniprotkb:SH3PX3(gene name synonym)|uniprotkb:SH3PXD3C(gene name synonym)|uniprotkb:SNX30(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040205|imex:IM-23549-65	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006891(EspF protein)|refseq:WP_000931693.1|refseq:NP_312577.1	"refseq:NP_695003.1|refseq:NP_001305075.1|ensembl:ENSG00000173548.9(gene)|ensembl:ENST00000308527.6(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0007032""(endosome organization)|go:""GO:0016020""(membrane)|go:""GO:0016197""(endosomal transport)|go:""GO:0017038""(protein import)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0042802""(identical protein binding)|go:""GO:0044351""(macropinocytosis)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0051044""(positive regulation of membrane protein ectodomain proteolysis)|go:""GO:0097320""(plasma membrane tubulation)|go:""GO:2000009""(negative regulation of protein localization to cell surface)|go:""GO:2000010""(positive regulation of protein localization to cell surface)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR036028|interpro:IPR036871|interpro:IPR037427|mint:Q8WV41|rcsb pdb:4AKV|panther:PTHR45827(orthology-group)"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:Xi+lGjtCtERpBpNdPvEPyVtkQlA83334	rogid:rhvspe+J40o9M1MJtpUIyeQFLRs9606	intact-crc:EA1B9E11E7E7DB8C|rigid:EJWElMHIfoLZPiYqkhIBXyoQTjI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9UQB8	uniprotkb:Q7DB77	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338.6	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Brain-specific angiogenesis inhibitor 1-associated protein 2(gene name synonym)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039977|imex:IM-23549-56	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000175866.16(gene)|ensembl:ENST00000321300.10(transcript)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001726""(ruffle)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0007409""(axonogenesis)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016358""(dendrite development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030141""(secretory granule)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030175""(filopodium)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043198""(dendritic shaft)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060076""(excitatory synapse)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0061845""(neuron projection branch point)|go:""GO:0061846""(dendritic spine cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:2000463""(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|panther:PTHR14206(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/12/31	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:E3BAF407E2E1FFFC|rigid:+FInGdMTTBxacaG2SJDoullzsRQ	false	-	sufficient binding region:333-558(IPR022639)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UM99	uniprotkb:Q9UQB8	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338.6	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Brain-specific angiogenesis inhibitor 1-associated protein 2(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040348|imex:IM-23549-97	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"ensembl:ENSG00000175866.16(gene)|ensembl:ENST00000321300.10(transcript)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001726""(ruffle)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0007409""(axonogenesis)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016358""(dendrite development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030141""(secretory granule)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030175""(filopodium)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043198""(dendritic shaft)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060076""(excitatory synapse)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0061845""(neuron projection branch point)|go:""GO:0061846""(dendritic spine cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:2000463""(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|panther:PTHR14206(orthology-group)"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/12/31	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	intact-crc:D248D0F818513943|rigid:ydlpfoKg2JP+g7zpvmz7rFp8Hww	false	sufficient binding region:338-550(IPR022639)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A2A2Y4	uniprotkb:Q8XAJ5	intact:EBI-6911547|uniprotkb:Q8N9L2|uniprotkb:Q53EP2|uniprotkb:Q5JV59|uniprotkb:A8MQB0|uniprotkb:B4DN14|uniprotkb:Q8IZ44|uniprotkb:Q5VZA1|uniprotkb:Q8N3Y5|uniprotkb:Q86WP8|ensembl:ENSP00000303508.3	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	psi-mi:frmd3_human(display_long)|uniprotkb:Band 4.1-like protein 4O(gene name synonym)|uniprotkb:EPB41L4O(gene name synonym)|uniprotkb:Ovary type protein 4.1(gene name synonym)|uniprotkb:FRMD3(gene name)|psi-mi:FRMD3(display_short)	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040232|imex:IM-23549-73	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001231888.1|refseq:NP_001231889.1|refseq:NP_001231890.1|refseq:NP_001231891.1|refseq:NP_777598.3|ensembl:ENSG00000172159.16(gene)|ensembl:ENST00000304195.8(transcript)|go:""GO:0005856""(cytoskeleton)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0016020""(membrane)|go:""GO:0031032""(actomyosin structure organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|panther:PTHR23280(orthology-group)"	refseq:WP_001025672.1|refseq:NP_309839.1	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:mhyjQ1Yy8dmn8JseI7ehX//yySw9606	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	intact-crc:9FBA2DEDA937175A|rigid:kms1NOgh7ZGGd3jJyLXtwhDJQr0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7DB85	uniprotkb:Q9Y5X1	intact:EBI-10038700|uniprotkb:Q7A9R0|uniprotkb:A0A0H3JQD8	intact:EBI-77848|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20|ensembl:ENSP00000376024.3|ensembl:ENSP00000506326.1	psi-mi:q7db85_eco57(display_long)|uniprotkb:espF(gene name)|psi-mi:espF(display_short)|uniprotkb:ECs_4550(orf name)	psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040209|imex:IM-23549-66	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006891(EspF protein)|refseq:WP_000931693.1|refseq:NP_312577.1	"refseq:NP_057308.1|panther:PTHR45827(orthology-group)|dip:DIP-30997N|ensembl:ENSG00000130340.17(gene)|ensembl:ENST00000392185.8(transcript)|ensembl:ENST00000679814.1(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0001726""(ruffle)|go:""GO:0005545""(1-phosphatidylinositol binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0016197""(endosomal transport)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032437""(cuticular plate)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0051044""(positive regulation of membrane protein ectodomain proteolysis)|go:""GO:0060988""(lipid tube assembly)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071933""(Arp2/3 complex binding)|go:""GO:0097320""(plasma membrane tubulation)|go:""GO:0098793""(presynapse)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|rcsb pdb:7OJ9|reactome:R-HSA-432722|reactome:R-HSA-8856828"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/23	rogid:Xi+lGjtCtERpBpNdPvEPyVtkQlA83334	rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606	intact-crc:8BAEA17474682211|rigid:GREPzuN+sA6TGjAc6ClCQYolaIk	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7DB77	uniprotkb:P49407	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581.2	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039968|imex:IM-23549-55	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_004032.2|refseq:NP_064647.1|dip:DIP-29979N|ensembl:ENSG00000137486.17(gene)|ensembl:ENST00000420843.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002031""(G protein-coupled receptor internalization)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0015031""(protein transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031143""(pseudopodium)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031701""(angiotensin receptor binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:1990763""(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|rcsb pdb:7R0C|rcsb pdb:7R0J|rcsb pdb:7SRS|rcsb pdb:8AS2|rcsb pdb:8AS3|rcsb pdb:8AS4|rcsb pdb:8JRV|rcsb pdb:8WRZ|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9839389|panther:PTHR11792(orthology-group)|ensembl:ENST00000360025.7|ensembl:ENSP00000353124.3|ensembl:ENSP00000409581.2"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/03/24	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606	intact-crc:27593252AF6C22B9|rigid:egVpT0wXvb3+UoIaPOCReuZ+1zM	false	sufficient binding region:333-558(IPR022639)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7DB77	uniprotkb:Q9UHR4	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-2483278|uniprotkb:A4D268|uniprotkb:Q75L21|uniprotkb:Q75L22|uniprotkb:Q96CV4|uniprotkb:Q9H5F5|uniprotkb:Q9Y2M8|ensembl:ENSP00000005260.8	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:bi2l1_human(display_long)|uniprotkb:BAIAP2L1(gene name)|psi-mi:BAIAP2L1(display_short)|uniprotkb:IRTKS(gene name synonym)|uniprotkb:Insulin receptor tyrosine kinase substrate(gene name synonym)|uniprotkb:Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039985|imex:IM-23549-57	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_061330.2|dip:DIP-53820N|ensembl:ENSG00000006453.14(gene)|ensembl:ENST00000005260.9(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030060|interpro:IPR035592|interpro:IPR036028|mint:Q9UHR4|rcsb pdb:2KXC|rcsb pdb:2LNH|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR14206(orthology-group)"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/27	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:ig7xSOv8h6Y4vYE0/n228+ZLWaM9606	intact-crc:656391477CCBE8E2|rigid:VE0c/Qjb0IzvfXI7VcEea+480MY	false	sufficient binding region:333-558(IPR022639)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UM99	uniprotkb:Q9UHR4	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-2483278|uniprotkb:A4D268|uniprotkb:Q75L21|uniprotkb:Q75L22|uniprotkb:Q96CV4|uniprotkb:Q9H5F5|uniprotkb:Q9Y2M8|ensembl:ENSP00000005260.8	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:bi2l1_human(display_long)|uniprotkb:BAIAP2L1(gene name)|psi-mi:BAIAP2L1(display_short)|uniprotkb:IRTKS(gene name synonym)|uniprotkb:Insulin receptor tyrosine kinase substrate(gene name synonym)|uniprotkb:Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040334|imex:IM-23549-95	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"refseq:NP_061330.2|dip:DIP-53820N|ensembl:ENSG00000006453.14(gene)|ensembl:ENST00000005260.9(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030060|interpro:IPR035592|interpro:IPR036028|mint:Q9UHR4|rcsb pdb:2KXC|rcsb pdb:2LNH|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR14206(orthology-group)"	-	-	-	figure legend:Fig. 5B|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/27	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:ig7xSOv8h6Y4vYE0/n228+ZLWaM9606	intact-crc:6C1664326CAD057F|rigid:YLb6A/iF7T7DYnGHWLiXbzYT1LA	false	sufficient binding region:338-550(IPR022639)	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TCX5	uniprotkb:Q7DB76	intact:EBI-746325|ensembl:ENSP00000289013.6|uniprotkb:Q8TAV1|uniprotkb:Q96PV9|intact:EBI-12011872	intact:EBI-10039068|uniprotkb:Q7A9Q0|uniprotkb:A0A0H3JJD5|uniprotkb:A0A6M0JL37	psi-mi:rhpn1_human(display_long)|uniprotkb:KIAA1929(gene name synonym)|uniprotkb:GTP-Rho-binding protein 1(gene name synonym)|uniprotkb:RHPN1(gene name)|psi-mi:RHPN1(display_short)	psi-mi:q7db76_eco57(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:ECs_4562(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039066|imex:IM-23549-20	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000158106.15(gene)|ensembl:ENST00000289013.11(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0051497""(negative regulation of stress fiber assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004328(BRO1)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR036034|interpro:IPR036274|interpro:IPR038499|interpro:IPR042715|interpro:IPR047138|mint:Q8TCX5|reactome:R-HSA-5666185|reactome:R-HSA-8980692|refseq:NP_443156.2|panther:PTHR23031(orthology-group)"	refseq:WP_000492638.1|interpro:IPR004959(IpaB/EvcA)|refseq:NP_312589.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:EF1IVH0DLg/1KL4iWFVBktsl5589606	rogid:xO5ymWP2ug1VLyxelIaeen+24gM83334	intact-crc:06379751D48A1F70|rigid:0Yiwj0imHykFHVs92LsiUMA6cao	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XA11	uniprotkb:O43257	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	intact:EBI-347522|ensembl:ENSP00000304593.2|uniprotkb:Q6IB12	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	psi-mi:znhi1_human(display_long)|uniprotkb:Cyclin-G1-binding protein 1(gene name synonym)|uniprotkb:Zinc finger protein subfamily 4A member 1(gene name synonym)|uniprotkb:p18 Hamlet(gene name synonym)|uniprotkb:ZNHIT1(gene name)|psi-mi:ZNHIT1(display_short)|uniprotkb:CGBP1(gene name synonym)|uniprotkb:ZNFN4A1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039022|imex:IM-23549-19	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	"ensembl:ENSG00000106400.12(gene)|ensembl:ENST00000305105.3(transcript)|go:""GO:0000786""(nucleosome)|go:""GO:0000812""(Swr1 complex)|go:""GO:0003015""(heart process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0031491""(nucleosome binding)|go:""GO:0036335""(intestinal stem cell homeostasis)|go:""GO:0042393""(histone binding)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:1902164""(obsolete positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:1905458""(positive regulation of lymphoid progenitor cell differentiation)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR039723|mint:O43257|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|refseq:NP_006340.1|panther:PTHR13093(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	rogid:Q7J5KSTTPql/B3mtDg1xvX0EWjw9606	intact-crc:8C71EEDC951EF37B|rigid:ZKzZi/Z6g5p/LPvOaXKz67zdspg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q93096	uniprotkb:Q8XAJ5	intact:EBI-1058467|uniprotkb:O00648|uniprotkb:Q49A54|uniprotkb:B2R6C8|intact:EBI-1640492|ensembl:ENSP00000485687.1|ensembl:ENSP00000497588.1|ensembl:ENSP00000500859.1|ensembl:ENSP00000500952.1|intact:EBI-21351791	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	"psi-mi:tp4a1_human(display_long)|uniprotkb:PTP4A1(gene name)|psi-mi:PTP4A1(display_short)|uniprotkb:PRL1(gene name synonym)|uniprotkb:PTPCAAX1(gene name synonym)|uniprotkb:""PTP(CAAXI)""(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 4a1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase of regenerating liver 1(gene name synonym)"	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039139|imex:IM-23549-25	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003454.1|refseq:XP_016866759.1|refseq:XP_016866760.1|ensembl:ENSG00000112245.14(gene)|ensembl:ENST00000626021.3(transcript)|ensembl:ENST00000648894.1(transcript)|ensembl:ENST00000672924.1(transcript)|ensembl:ENST00000673199.1(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005819""(spindle)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR020422|interpro:IPR029021|interpro:IPR050561|mint:Q93096|rcsb pdb:1RXD|rcsb pdb:1XM2|rcsb pdb:5BX1|refseq:XP_011534413.1|refseq:XP_011534414.1|panther:PTHR23339(orthology-group)"	refseq:WP_001025672.1|refseq:NP_309839.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:Eza5NsYNd+5ml6QEEmkQv5pAZ789606	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	intact-crc:907A5D92E9B6E39E|rigid:34CyLoE6+8jRAPYLPlLJhU14uWc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q68DY1	uniprotkb:P0DJ88	intact:EBI-1640399|uniprotkb:Q8N8T4|uniprotkb:Q96QM1|ensembl:ENSP00000469958.1	intact:EBI-10039462|uniprotkb:Q8X2D5|uniprotkb:P0DJ89	psi-mi:zn626_human(display_long)|uniprotkb:ZNF626(gene name)|psi-mi:ZNF626(display_short)	"psi-mi:esfu2_eco57(display_long)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:ECs2715(locus name)"	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039475|imex:IM-23549-38	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001070143.1|refseq:NP_660340.1|ensembl:ENSG00000188171.17(gene)|ensembl:ENST00000601440.6(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR050636|reactome:R-HSA-212436|panther:PTHR24384(orthology-group)"	"go:""GO:0005576""(extracellular region)|interpro:IPR006891(EspF protein)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0009405""(obsolete pathogenesis)|refseq:NP_310742.1|refseq:WP_010917831.1|rcsb pdb:2K42|rcsb pdb:2KXC|rcsb pdb:2LNH|dip:DIP-59949N"	-	-	caution:This sequence has been withdrawn from Uniprot.	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:tF3sX34c5wSVHW6nCDA2edNG6hg9606	rogid:WARX33S3/G5CXG922GIjofxveNc83334	intact-crc:7DF810628E66DC2A|rigid:pD9kpgdQB2avZ5vudg31ytsFOP4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13287	uniprotkb:Q7DB50	intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|ensembl:ENSP00000243346.5|uniprotkb:B5BU69	intact:EBI-6379656|uniprotkb:Q7A9M3|uniprotkb:A0A6M0JN46	psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym)	psi-mi:q7db50_eco57(display_long)|uniprotkb:espG(gene name)|psi-mi:espG(display_short)|uniprotkb:ECs_4590(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038746|imex:IM-23549-6	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000123609.11(gene)|ensembl:ENST00000243346.10(transcript)|go:""GO:0002281""(macrophage activation involved in immune response)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0032687""(negative regulation of interferon-alpha production)|go:""GO:0032688""(negative regulation of interferon-beta production)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902524""(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q13287|reactome:R-HSA-9692916|refseq:NP_004679.2|refseq:XP_005246998.1|refseq:XP_016860736.1|panther:PTHR15225(orthology-group)"	"interpro:IPR009669(EspG)|rcsb pdb:3PCR|rcsb pdb:3PCS|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|refseq:WP_001301460.1|interpro:IPR043098|go:""GO:0004197""(cysteine-type endopeptidase activity)|refseq:NP_312617.1"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606	rogid:g7FQ+G0CKEqSrzN+2H+OAnLu7No83334	intact-crc:5DEC59F141B1C4C8|rigid:ECozAgrWsBgj/lxMRGMTozaWyr8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y5X1	uniprotkb:Q7DB85	intact:EBI-77848|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20|ensembl:ENSP00000376024.3|ensembl:ENSP00000506326.1	intact:EBI-10038700|uniprotkb:Q7A9R0|uniprotkb:A0A0H3JQD8	psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym)	psi-mi:q7db85_eco57(display_long)|uniprotkb:espF(gene name)|psi-mi:espF(display_short)|uniprotkb:ECs_4550(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038742|imex:IM-23549-5	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057308.1|panther:PTHR45827(orthology-group)|dip:DIP-30997N|ensembl:ENSG00000130340.17(gene)|ensembl:ENST00000392185.8(transcript)|ensembl:ENST00000679814.1(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0001726""(ruffle)|go:""GO:0005545""(1-phosphatidylinositol binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0016197""(endosomal transport)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032437""(cuticular plate)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0051044""(positive regulation of membrane protein ectodomain proteolysis)|go:""GO:0060988""(lipid tube assembly)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071933""(Arp2/3 complex binding)|go:""GO:0097320""(plasma membrane tubulation)|go:""GO:0098793""(presynapse)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|rcsb pdb:7OJ9|reactome:R-HSA-432722|reactome:R-HSA-8856828"	interpro:IPR006891(EspF protein)|refseq:WP_000931693.1|refseq:NP_312577.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/23	rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606	rogid:Xi+lGjtCtERpBpNdPvEPyVtkQlA83334	intact-crc:246569FACCAC2AC9|rigid:GREPzuN+sA6TGjAc6ClCQYolaIk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43414	uniprotkb:Q8XAL7	intact:EBI-9679612|ensembl:ENSP00000361331.2|uniprotkb:B1AK98|uniprotkb:Q5T2T7|uniprotkb:Q5T2T9|uniprotkb:Q5TG35|uniprotkb:Q9BQA0|uniprotkb:Q9UEB4	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:eri3_human(display_long)|uniprotkb:ERI3(gene name)|psi-mi:ERI3(display_short)|uniprotkb:PINT1(gene name synonym)|uniprotkb:PRNPIP(gene name synonym)|uniprotkb:PRNPIP1(gene name synonym)|uniprotkb:Prion interactor 1(gene name synonym)|uniprotkb:Prion protein-interacting protein(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039429|imex:IM-23549-34	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000117419.16(gene)|ensembl:ENST00000372257.7(transcript)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000467""(""exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0003723""(RNA binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036397|interpro:IPR047201|interpro:IPR051274|mint:O43414|rcsb pdb:2XRI|rcsb pdb:7K05|rcsb pdb:7K06|rcsb pdb:7K07|rcsb pdb:7LPY|rcsb pdb:7LPZ|rcsb pdb:7LQ0|refseq:NP_076971.1|refseq:NP_001288627.1|refseq:NP_001288628.1|refseq:NP_001288629.1|refseq:NP_001288630.1|panther:PTHR23044(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:Ke3BT8EH5uiVr+FunIbBBwvh/bM9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:18806B2F9D5C976D|rigid:0ZVXKihI+3/vwEnITaIrN+fXQ4E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H3R5	uniprotkb:Q8XB62	intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006.2	intact:EBI-10038787|uniprotkb:Q7ACX7|uniprotkb:A0A0H3JG75|uniprotkb:A0A6M0JSQ6	psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short)	psi-mi:q8xb62_eco57(display_long)|uniprotkb:espJ(gene name)|psi-mi:espJ(display_short)|uniprotkb:ECs_2714(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038796|imex:IM-23549-7	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_075060.1|ensembl:ENSG00000153044.10(gene)|ensembl:ENST00000283006.7(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000939""(inner kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007059""(chromosome segregation)|go:""GO:0043515""(kinetochore binding)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0051383""(kinetochore organization)|interpro:IPR008426(Centromere H)|interpro:IPR040034|mint:Q9H3R5|rcsb pdb:7PB4|rcsb pdb:7PKN|rcsb pdb:7QOO|rcsb pdb:7R5S|rcsb pdb:7R5V|rcsb pdb:7XHN|rcsb pdb:7XHO|rcsb pdb:7YWX|rcsb pdb:7YYH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|panther:PTHR48122(orthology-group)"	refseq:WP_000022458.1|interpro:IPR015226(AvrPphF ORF-2)|refseq:NP_310741.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606	rogid:pwnhf6VxgSKHIqJxvoUGpqp7Iu083334	intact-crc:B87A8A8D7BEACE53|rigid:E2ee4xRBiu3oDMgP8APRWAyxul4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XA11	uniprotkb:P20807	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	intact:EBI-5655000|uniprotkb:Q9Y5S6|uniprotkb:Q9Y5S7|uniprotkb:Q9BTU4|uniprotkb:A6H8K6|uniprotkb:Q7L4R0|uniprotkb:Q9BQC8|ensembl:ENSP00000380349.3	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	psi-mi:can3_human(display_long)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038917|imex:IM-23549-12	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	"efo:""Orphanet:267""|efo:""Orphanet:565909""|ensembl:ENSG00000092529.26(gene)|ensembl:ENST00000397163.8(transcript)|go:""GO:0003824""(catalytic activity)|go:""GO:0004198""(calcium-dependent cysteine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006915""(apoptotic process)|go:""GO:0007517""(muscle organ development)|go:""GO:0008233""(peptidase activity)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0014718""(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:""GO:0014850""(response to muscle activity)|go:""GO:0030016""(myofibril)|go:""GO:0030018""(Z disc)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030239""(myofibril assembly)|go:""GO:0030315""(T-tubule)|go:""GO:0031402""(sodium ion binding)|go:""GO:0031432""(titin binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045661""(regulation of myoblast differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0050790""(regulation of catalytic activity)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051592""(response to calcium ion)|go:""GO:0055103""(ligase regulator activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061061""(muscle structure development)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070315""(G1 to G0 transition involved in cell differentiation)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:0071472""(cellular response to salt stress)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0097264""(self proteolysis)|go:""GO:1990092""(calcium-dependent self proteolysis)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029531|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR054069|mint:P20807|rcsb pdb:4OKH|rcsb pdb:6BDT|rcsb pdb:6BGP|rcsb pdb:6BJD|rcsb pdb:6BKJ|reactome:R-HSA-1474228|refseq:NP_000061.1|refseq:NP_077320.1|refseq:NP_775110.1|refseq:NP_775111.1|refseq:NP_775112.1|refseq:NP_775113.1|panther:PTHR10183(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	rogid:niIxeCH+wcEYovZ1/3/zTO27bOU9606	intact-crc:2ABE3A9A3F90820F|rigid:5aDXr/CU6pc4B6YyM+GJJg7B2LI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XB62	uniprotkb:Q9NPQ8	intact:EBI-10038787|uniprotkb:Q7ACX7|uniprotkb:A0A0H3JG75|uniprotkb:A0A6M0JSQ6	intact:EBI-717509|uniprotkb:Q0P508|uniprotkb:Q2T9J1|uniprotkb:Q7Z352|uniprotkb:Q96EZ1|uniprotkb:Q96SZ2|uniprotkb:Q9H064|uniprotkb:Q9H5H3|uniprotkb:Q9H9E7|ensembl:ENSP00000432008.1	psi-mi:q8xb62_eco57(display_long)|uniprotkb:espJ(gene name)|psi-mi:espJ(display_short)|uniprotkb:ECs_2714(orf name)	psi-mi:ric8a_human(display_long)|uniprotkb:RIC8A(gene name)|psi-mi:RIC8A(display_short)|uniprotkb:Synembryn-A(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038846|imex:IM-23549-10	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000022458.1|interpro:IPR015226(AvrPphF ORF-2)|refseq:NP_310741.1	"refseq:NP_001273063.1|refseq:NP_068751.4|refseq:XP_016873596.1|ensembl:ENSG00000177963.15(gene)|ensembl:ENST00000526104.6(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001944""(vasculature development)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0008542""(visual learning)|go:""GO:0042074""(cell migration involved in gastrulation)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0070586""(cell-cell adhesion involved in gastrulation)|go:""GO:0071711""(basement membrane organization)|interpro:IPR008376(Synembryn)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019318|mint:Q9NPQ8|panther:PTHR12425(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:pwnhf6VxgSKHIqJxvoUGpqp7Iu083334	rogid:jNCxRLnDY2aSw6SMtE82Tny1IE89606	intact-crc:10AF5A4B1D1EF48B|rigid:G9MzjwIAron9qJW3oXc71+l1qos	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3C8	uniprotkb:Q8XAL6	intact:EBI-1045733|uniprotkb:Q5VTX1|uniprotkb:Q549X0|uniprotkb:Q9BS96|uniprotkb:Q9P009|uniprotkb:D3DVF9|uniprotkb:A8K9R1|ensembl:ENSP00000356982.5	intact:EBI-10039443|uniprotkb:Q7AEN0|uniprotkb:A0A0H3JE77|uniprotkb:A0A6M0JRG2	psi-mi:ufc1_human(display_long)|uniprotkb:UFC1(gene name)|psi-mi:UFC1(display_short)|uniprotkb:CGI-126(orf name)|uniprotkb:HSPC155(orf name)	psi-mi:q8xal6_eco57(display_long)|uniprotkb:nleH1_2(gene name)|psi-mi:nleH1_2(display_short)|uniprotkb:ECs_1814(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039453|imex:IM-23549-37	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057490.2|refseq:XP_016856939.1|refseq:XP_016856940.1|ensembl:ENSG00000143222.12(gene)|ensembl:ENST00000368003.6(transcript)|go:""GO:0007420""(brain development)|go:""GO:0032649""(regulation of type II interferon production)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0061657""(UFM1 conjugating enzyme activity)|go:""GO:0061709""(reticulophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071568""(UFM1 transferase activity)|go:""GO:0071569""(protein ufmylation)|go:""GO:1990592""(protein K69-linked ufmylation)|interpro:IPR014806(Protein of unknown function DUF1782)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|rcsb pdb:2K07|rcsb pdb:2Z6O|rcsb pdb:2Z6P|rcsb pdb:3EVX|rcsb pdb:7NVJ|rcsb pdb:7NVK|rcsb pdb:7NW1|rcsb pdb:7OVC|rcsb pdb:8BZR|rcsb pdb:8C0D|panther:PTHR12921(orthology-group)"	"refseq:WP_000950979.1|dip:DIP-60659N|go:""GO:0140403""(effector-mediated suppression of host innate immune response)|go:""GO:0140416""(transcription regulator inhibitor activity)|interpro:IPR054466|rcsb pdb:4LRK|rcsb pdb:4O96|refseq:NP_309841.1"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:qM6IH1SjQcAXszcGGqin8bLe4Pk9606	rogid:enXU0hiDHv8QGNYEh1mXmMzST+083334	intact-crc:AD6D3F613111A780|rigid:qQhhjv5rf7/qgc8EsnuxZL2GdT4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01210	uniprotkb:Q8XAJ5	intact:EBI-6656032|uniprotkb:B2RC23|uniprotkb:Q6FHC6|uniprotkb:Q6FHE6|ensembl:ENSP00000324248.3|ensembl:ENSP00000400894.2	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	psi-mi:penk_human(display_long)|uniprotkb:PENK(gene name)|psi-mi:PENK(display_short)	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039135|imex:IM-23549-24	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001129162.1|ensembl:ENSG00000181195.11(gene)|ensembl:ENST00000314922.3(transcript)|ensembl:ENST00000451791.7(transcript)|go:""GO:0001515""(opioid peptide activity)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001662""(behavioral fear response)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001964""(startle response)|go:""GO:0002118""(aggressive behavior)|go:""GO:0005184""(neuropeptide hormone activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007600""(sensory perception)|go:""GO:0009636""(response to toxic substance)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0019226""(transmission of nerve impulse)|go:""GO:0019233""(sensory perception of pain)|go:""GO:0030425""(dendrite)|go:""GO:0031628""(opioid receptor binding)|go:""GO:0032280""(symmetric synapse)|go:""GO:0032355""(response to estradiol)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0034466""(chromaffin granule lumen)|go:""GO:0034592""(synaptic vesicle lumen)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035094""(response to nicotine)|go:""GO:0035641""(locomotory exploration behavior)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0038003""(G protein-coupled opioid receptor signaling pathway)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043204""(perikaryon)|go:""GO:0043679""(axon terminus)|go:""GO:0045471""(response to ethanol)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051867""(general adaptation syndrome, behavioral process)|go:""GO:0070852""(cell body fiber)|go:""GO:0071305""(cellular response to vitamin D)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071871""(response to epinephrine)|go:""GO:0098586""(cellular response to virus)|go:""GO:0099013""(neuronal dense core vesicle lumen)|go:""GO:0099538""(synaptic signaling via neuropeptide)|go:""GO:2000987""(positive regulation of behavioral fear response)|interpro:IPR000703(Proenkephalin A)|interpro:IPR006024(Opioid neuropeptide precursor)|rcsb pdb:1PLW|rcsb pdb:1PLX|rcsb pdb:2LWC|rcsb pdb:5E33|rcsb pdb:5E3A|rcsb pdb:8JGF|rcsb pdb:8JGG|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-418594|reactome:R-HSA-8957275|panther:PTHR11438(orthology-group)"	refseq:WP_001025672.1|refseq:NP_309839.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:xL8ujOb7RFDy5+t+Oe/ph/XOoOM9606	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	intact-crc:521A06ECCDCE3F30|rigid:KpaHhap6NOsiixUq12D75qNbINA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XBX8	uniprotkb:Q8N456	intact:EBI-10039153|uniprotkb:Q7AAV0|uniprotkb:A0A0H3JHS6|uniprotkb:A0A6M0JF43	intact:EBI-751373|uniprotkb:Q6UY02|ensembl:ENSP00000363275.3	psi-mi:nleb1_eco57(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:ECs3857(locus name)	psi-mi:lrc18_human(display_long)|uniprotkb:LRRC18(gene name)|psi-mi:LRRC18(display_short)|uniprotkb:UNQ9338/PRO34010(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039173|imex:IM-23549-27	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000953022.1|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|refseq:NP_311884.1"	"refseq:NP_001006940.3|refseq:XP_006717930.1|refseq:XP_011538124.1|refseq:XP_011538125.1|refseq:XP_011538128.1|refseq:XP_011538130.1|refseq:XP_011538131.1|ensembl:ENSG00000165383.12(gene)|ensembl:ENST00000374160.8(transcript)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0035556""(intracellular signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050216|refseq:XP_016871765.1|refseq:XP_016871766.1|panther:PTHR45752(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:s08ivrjNoMdHHNcIwH+V7ZobNOQ83334	rogid:gKc5evWyzPYpUr8KIzDu4I9Oy4A9606	intact-crc:B91ED4E6F6C2EED4|rigid:pzu4CXPHcWRY1b3GSazXdFoXPU4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XA11	uniprotkb:Q96HQ2	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	intact:EBI-10038935|uniprotkb:Q8WVE3|ensembl:ENSP00000394183.2	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	psi-mi:c2ail_human(display_long)|uniprotkb:CDKN2AIPNL(gene name)|psi-mi:CDKN2AIPNL(display_short)|uniprotkb:CDKN2A-interacting protein N-terminal-like protein(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038949|imex:IM-23549-13	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	refseq:NP_542387.1|dip:DIP-61982N|ensembl:ENSG00000237190.4(gene)|ensembl:ENST00000458198.3(transcript)|interpro:IPR021859|mint:Q96HQ2	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/12/22	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	rogid:D9Y5uROpQokbORFnDCrBSgHRTHc9606	intact-crc:AF615BBD69963CED|rigid:7/P51M3xeh+kbvOIp9l87t6D/nc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UK73	uniprotkb:A0A0H3JFN8	intact:EBI-310482|uniprotkb:O43146|ensembl:ENSP00000307298.4	intact:EBI-10038897|uniprotkb:A0A4P8BA24	psi-mi:fem1b_human(display_long)|uniprotkb:FEM1B(gene name)|psi-mi:FEM1B(display_short)|uniprotkb:KIAA0396(gene name synonym)|uniprotkb:F1AA(gene name synonym)|uniprotkb:FEM1-beta(gene name synonym)|uniprotkb:Fem-1-like death receptor-binding protein alpha(gene name synonym)|uniprotkb:Fem-1-like in apoptotic pathway protein alpha(gene name synonym)	psi-mi:a0a0h3jfn8_eco57(display_long)|uniprotkb:espO1-1(gene name)|psi-mi:espO1-1(display_short)|uniprotkb:ECs_1567(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038902|imex:IM-23549-11	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056137.1|ensembl:ENSG00000169018.6(gene)|ensembl:ENST00000306917.5(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0005123""(death receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051438""(regulation of ubiquitin-protein transferase activity)|go:""GO:0060442""(branching involved in prostate gland morphogenesis)|go:""GO:0060743""(epithelial cell maturation involved in prostate gland development)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000001""(regulation of DNA damage checkpoint)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:Q9UK73|rcsb pdb:6LBF|rcsb pdb:7CNG|rcsb pdb:7EL6|rcsb pdb:8IJ1|rcsb pdb:8JE1|rcsb pdb:8JE2|rcsb pdb:8WQA|rcsb pdb:8WQB|rcsb pdb:8WQC|rcsb pdb:8WQD|rcsb pdb:8WQE|rcsb pdb:8WQF|rcsb pdb:8WQG|rcsb pdb:8WQH|rcsb pdb:8WQI|reactome:R-HSA-8951664|dip:DIP-31663N|panther:PTHR24173(orthology-group)"	uniprotkb:Q8X3G1(uniprot-removed-ac)|refseq:WP_001303921.1|refseq:NP_309594.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/27	rogid:ODOxw01NrJ8fUJv2XopsdTYtAr49606	rogid:xkpMwN9ZoiqOVRPjfxcowfXdmbk83334	intact-crc:D25B8B5E62346144|rigid:pbujLiJp+Q7BJEt7OA0edUpkim4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XB62	uniprotkb:Q96HT8	intact:EBI-10038787|uniprotkb:Q7ACX7|uniprotkb:A0A0H3JG75|uniprotkb:A0A6M0JSQ6	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154.6	psi-mi:q8xb62_eco57(display_long)|uniprotkb:espJ(gene name)|psi-mi:espJ(display_short)|uniprotkb:ECs_2714(orf name)	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038835|imex:IM-23549-9	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000022458.1|interpro:IPR015226(AvrPphF ORF-2)|refseq:NP_310741.1	"refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988.11(gene)|ensembl:ENST00000320848.7(transcript)|go:""GO:0042802""(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|panther:PTHR31324(orthology-group)"	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/10	rogid:pwnhf6VxgSKHIqJxvoUGpqp7Iu083334	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	intact-crc:77D0ACED8992A01C|rigid:B4DOPbQLC1N4Bvf5sgdEq9FpAVo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62191	uniprotkb:Q8XA11	intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|uniprotkb:Q6NW36|uniprotkb:B4DR63|ensembl:ENSP00000261303.8	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym)	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039018|imex:IM-23549-18	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002793.2|ensembl:ENSG00000100764.14(gene)|ensembl:ENST00000261303.13(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|refseq:NP_001317141.1|refseq:XP_016876959.1|panther:PTHR23073(orthology-group)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	intact-crc:E8DCE1ED3594DCF4|rigid:BQnzh2juILO/0YE9dI5RQvjokTc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96IZ6	uniprotkb:A0A0H3JGR6	intact:EBI-7211882|uniprotkb:A6NNC4|uniprotkb:Q9P0B5|uniprotkb:Q9H9G9|uniprotkb:Q9NUI8|intact:MINT-3054259|ensembl:ENSP00000309610.6	intact:EBI-10039274|uniprotkb:A0A7U8R338|uniprotkb:A0A6M0JIH9|uniprotkb:A0A6M7CAZ4	psi-mi:met2a_human(display_long)|uniprotkb:METTL2A(gene name)|psi-mi:METTL2A(display_short)|uniprotkb:METTL2(gene name synonym)|uniprotkb:Methyltransferase-like protein 2A(gene name synonym)|uniprotkb:HSPC266(orf name)	psi-mi:a0a0h3jgr6_eco57(display_long)|uniprotkb:nleD(gene name)|psi-mi:nleD(display_short)|uniprotkb:ECs_0850(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039258|imex:IM-23549-31	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_859076.3|ensembl:ENSG00000087995.16(gene)|ensembl:ENST00000311506.10(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0006399""(tRNA metabolic process)|go:""GO:0006400""(tRNA modification)|go:""GO:0030488""(tRNA methylation)|go:""GO:0052735""(""tRNA (cytidine-3-)-methyltransferase activity"")|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR026113|interpro:IPR029063|mint:Q96IZ6|panther:PTHR22809(orthology-group)"	uniprotkb:Q7AGE0(uniprot-removed-ac)|refseq:WP_001247925.1|interpro:IPR028208|refseq:NP_308877.1	-	comment:mint|function:Probable methyltransferase|comment:homomint	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:UDMjkoiVoFtAUI7N3PDqj5ELSFI9606	rogid:zkF+5p88ddmXoI6VON0GRkdetcU83334	intact-crc:E6BDC7E67B71EE63|rigid:mLvQ55YwmTtroKvdTxrjyulJLrQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61968	uniprotkb:Q8XAL7	intact:EBI-2798728|uniprotkb:O00158|uniprotkb:O88894|ensembl:ENSP00000359573.1|ensembl:ENSP00000359575.4|uniprotkb:D3DT23	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:lmo4_human(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:LMO4(gene name)|psi-mi:LMO4(display_short)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039433|imex:IM-23549-35	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006760.1|ensembl:ENSG00000143013.13(gene)|ensembl:ENST00000370542.1(transcript)|ensembl:ENST00000370544.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001843""(neural tube closure)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0021514""(ventral spinal cord interneuron differentiation)|go:""GO:0021520""(spinal cord motor neuron cell fate specification)|go:""GO:0021527""(spinal cord association neuron differentiation)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0031252""(cell leading edge)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0042659""(regulation of cell fate specification)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048538""(thymus development)|go:""GO:0050865""(regulation of cell activation)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR050945|mint:P61968|rcsb pdb:9F5B|refseq:XP_005271348.1|dip:DIP-41414N|panther:PTHR45787(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	crc64:C8AC295144AD7787	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/24	rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:9D7CF2EF304DE6FF|rigid:j6OcLTceI60gI9OtnstDrWiBRvw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6Y2X3	uniprotkb:Q8XA11	intact:EBI-10038974|uniprotkb:A5YM67|uniprotkb:Q17RY2|uniprotkb:Q66K17|uniprotkb:Q96N59|uniprotkb:Q96T63|ensembl:ENSP00000317500.5|ensembl:ENSP00000350223.3|ensembl:ENSP00000448876.2|ensembl:ENSP00000450196.2|ensembl:ENSP00000504134.1	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	psi-mi:djc14_human(display_long)|uniprotkb:DNAJC14(gene name)|psi-mi:DNAJC14(display_short)|uniprotkb:DRIP78(gene name synonym)|uniprotkb:HDJ3(gene name synonym)|uniprotkb:DnaJ protein homolog 3(gene name synonym)|uniprotkb:Dopamine receptor-interacting protein of 78 kDa(gene name synonym)|uniprotkb:Human DnaJ protein 3(gene name synonym)	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039004|imex:IM-23549-15	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115740.5|ensembl:ENSG00000135392.19(gene)|ensembl:ENST00000317287.5(transcript)|ensembl:ENST00000357606.7(transcript)|ensembl:ENST00000546957.2(transcript)|ensembl:ENST00000547445.2(transcript)|ensembl:ENST00000678005.2(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0050780""(dopamine receptor binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR032843|interpro:IPR036869|interpro:IPR052317|mint:Q6Y2X3|panther:PTHR44665(orthology-group)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:oS3c968UKq0i0JRZxUJFskA5HD89606	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	intact-crc:063928598B26FFDE|rigid:zrdoJVyFVTprLL5aBAyHrVWpLOk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P56555	uniprotkb:Q8XAJ5	intact:EBI-10039117|uniprotkb:Q4VB31	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	psi-mi:dscr4_human(display_long)|uniprotkb:DSCR4(gene name)|psi-mi:DSCR4(display_short)|uniprotkb:DCRB(gene name synonym)|uniprotkb:DSCRB(gene name synonym)|uniprotkb:Down syndrome critical region protein B(gene name synonym)	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039115|imex:IM-23549-22	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_005858.1	refseq:WP_001025672.1|refseq:NP_309839.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:ObILr2wYLN3Wg8advbNI6ZaAta89606	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	intact-crc:506E099E0E0569BB|rigid:FcSGEjJGaaly873gwKO+F9MXyfs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q05D32	uniprotkb:Q8X834	intact:EBI-10039222|uniprotkb:Q3ZTU1|uniprotkb:Q6AI06|uniprotkb:Q8IYI9|uniprotkb:Q9NVT2|uniprotkb:Q9NZX8|uniprotkb:Q9P030|ensembl:ENSP00000260327.4|ensembl:ENSP00000452837.1	intact:EBI-10039193|uniprotkb:A0A7U8R4U9|uniprotkb:Q7AGE2|uniprotkb:A0A6M0JJK4|uniprotkb:A0A6M6W2Q6	psi-mi:ctsl2_human(display_long)|uniprotkb:HSPC058(orf name)|uniprotkb:HSPC129(orf name)|uniprotkb:CTDSPL2(gene name)|psi-mi:CTDSPL2(display_short)	psi-mi:q8x834_eco57(display_long)|uniprotkb:nleC(gene name)|psi-mi:nleC(display_short)|uniprotkb:ECs_0847(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039220|imex:IM-23549-30	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057480.2|refseq:XP_005254498.1|refseq:XP_006720628.1|ensembl:ENSG00000137770.14(gene)|ensembl:ENST00000260327.9(transcript)|ensembl:ENST00000558966.5(transcript)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0008420""(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0046827""(positive regulation of protein export from nucleus)|interpro:IPR004274(NLI interacting factor)|interpro:IPR011948(Dullard-like phosphatase domain)|interpro:IPR023214|interpro:IPR036412|interpro:IPR050365|mint:Q05D32|panther:PTHR12210(orthology-group)"	"interpro:IPR025208|go:""GO:0046872""(metal ion binding)|rcsb pdb:4LGI|rcsb pdb:4LGJ|mint:Q8X834|refseq:NP_308874.1"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:hJqS+nt0dbuxyyr3etxclNYAZco9606	rogid:2YRFou+gcur7JjPuYwcTJn7Rrpo83334	intact-crc:0441FCBC0DECDDA0|rigid:x+MOliNepmWeZDt+CFJkg8Gy/HY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y4M8	uniprotkb:Q8X834	intact:EBI-10039207	intact:EBI-10039193|uniprotkb:A0A7U8R4U9|uniprotkb:Q7AGE2|uniprotkb:A0A6M0JJK4|uniprotkb:A0A6M6W2Q6	psi-mi:ch071_human(display_long)|uniprotkb:LINC00588(gene name)|psi-mi:LINC00588(display_short)|uniprotkb:C8orf71(gene name synonym)	psi-mi:q8x834_eco57(display_long)|uniprotkb:nleC(gene name)|psi-mi:nleC(display_short)|uniprotkb:ECs_0847(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039205|imex:IM-23549-29	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR025208|go:""GO:0046872""(metal ion binding)|rcsb pdb:4LGI|rcsb pdb:4LGJ|mint:Q8X834|refseq:NP_308874.1"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:24v/Quf+HxPH2yvmmV5uFTFhZxw9606	rogid:2YRFou+gcur7JjPuYwcTJn7Rrpo83334	intact-crc:225079DDC774DA5D|rigid:ghnYVKZPaXkwQ+NDJyGINYnnd0E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XAL7	uniprotkb:P00374	intact:EBI-10039292|uniprotkb:Q7AEM9	intact:EBI-10039315|uniprotkb:B4DDD2|uniprotkb:Q14130|uniprotkb:Q6IRW8|ensembl:ENSP00000396308.2|ensembl:ENSP00000426474.1	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	psi-mi:dyr_human(display_long)|uniprotkb:DHFR(gene name)|psi-mi:DHFR(display_short)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039425|imex:IM-23549-33	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	"rcsb pdb:2W3A|ensembl:ENSG00000228716.7(gene)|ensembl:ENST00000439211.7(transcript)|ensembl:ENST00000505337.5(transcript)|go:""GO:0000900""(mRNA regulatory element binding translation repressor activity)|go:""GO:0003729""(mRNA binding)|go:""GO:0004146""(dihydrofolate reductase activity)|go:""GO:0005542""(folic acid binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006729""(tetrahydrobiopterin biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031103""(axon regeneration)|go:""GO:0031427""(response to methotrexate)|go:""GO:0046452""(dihydrofolate metabolic process)|go:""GO:0046653""(tetrahydrofolate metabolic process)|go:""GO:0046654""(tetrahydrofolate biosynthetic process)|go:""GO:0046655""(folic acid metabolic process)|go:""GO:0050661""(NADP binding)|go:""GO:0051000""(positive regulation of nitric-oxide synthase activity)|go:""GO:0070402""(NADPH binding)|go:""GO:1990825""(sequence-specific mRNA binding)|go:""GO:2000121""(regulation of removal of superoxide radicals)|interpro:IPR001796(Dihydrofolate reductase region)|interpro:IPR012259(Dihydrofolate reductase)|interpro:IPR017925|interpro:IPR024072|rcsb pdb:2W3B|mint:P00374|rcsb pdb:1BOZ|rcsb pdb:1DHF|rcsb pdb:1DLR|rcsb pdb:1DLS|rcsb pdb:1DRF|rcsb pdb:1HFP|rcsb pdb:1HFQ|rcsb pdb:1HFR|rcsb pdb:1KMS|rcsb pdb:1KMV|rcsb pdb:1MVS|rcsb pdb:1MVT|rcsb pdb:1OHJ|rcsb pdb:1OHK|rcsb pdb:1PD8|rcsb pdb:1PD9|rcsb pdb:1PDB|rcsb pdb:1S3U|rcsb pdb:1S3V|rcsb pdb:1S3W|rcsb pdb:1U71|rcsb pdb:1U72|rcsb pdb:1YHO|rcsb pdb:2C2S|rcsb pdb:2C2T|rcsb pdb:2DHF|rcsb pdb:2W3M|rcsb pdb:3EIG|rcsb pdb:3F8Y|rcsb pdb:3F8Z|rcsb pdb:3F91|rcsb pdb:3FS6|rcsb pdb:3GHC|rcsb pdb:3GHV|rcsb pdb:3GHW|rcsb pdb:3GI2|rcsb pdb:3GYF|rcsb pdb:3L3R|rcsb pdb:3N0H|rcsb pdb:3NTZ|rcsb pdb:3NU0|rcsb pdb:3NXO|rcsb pdb:3NXR|rcsb pdb:3NXT|rcsb pdb:3NXV|rcsb pdb:3NXX|rcsb pdb:3NXY|rcsb pdb:3NZD|rcsb pdb:3OAF|rcsb pdb:3S3V|rcsb pdb:3S7A|rcsb pdb:4DDR|rcsb pdb:4G95|rcsb pdb:4KAK|rcsb pdb:4KBN|rcsb pdb:4KD7|rcsb pdb:4KEB|rcsb pdb:4KFJ|rcsb pdb:4M6J|rcsb pdb:4M6K|rcsb pdb:4M6L|rcsb pdb:4QHV|rcsb pdb:4QJC|rcsb pdb:5HPB|rcsb pdb:5HQY|rcsb pdb:5HQZ|rcsb pdb:5HSR|rcsb pdb:5HSU|rcsb pdb:5HT4|rcsb pdb:5HT5|rcsb pdb:5HUI|rcsb pdb:5HVB|rcsb pdb:5HVE|rcsb pdb:5SD6|rcsb pdb:5SD7|rcsb pdb:5SD8|rcsb pdb:5SD9|rcsb pdb:5SDA|rcsb pdb:5SDB|rcsb pdb:6A7C|rcsb pdb:6A7E|rcsb pdb:6DAV|rcsb pdb:6DE4|rcsb pdb:6VCJ|rcsb pdb:7ESE|rcsb pdb:7XI7|rcsb pdb:8WGN|reactome:R-HSA-1474151|reactome:R-HSA-196757|reactome:R-HSA-69205|refseq:NP_000782.1|refseq:NP_001277283.1|panther:PTHR48069(orthology-group)|efo:""Orphanet:319651"""	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	rogid:4yoitO/ETpazAN2OtD/rXCte4289606	intact-crc:1949A02D144A12F6|rigid:BwRxu/G90K7THotPE+clPdJgMdQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7DB85	uniprotkb:Q9UI95	intact:EBI-10038700|uniprotkb:Q7A9R0|uniprotkb:A0A0H3JQD8	intact:EBI-77889|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3|ensembl:ENSP00000235310.2|ensembl:ENSP00000365855.3|ensembl:ENSP00000365882.4|ensembl:ENSP00000400982.2	psi-mi:q7db85_eco57(display_long)|uniprotkb:espF(gene name)|psi-mi:espF(display_short)|uniprotkb:ECs_4550(orf name)	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038698|imex:IM-23549-3	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006891(EspF protein)|refseq:WP_000931693.1|refseq:NP_312577.1	"panther:PTHR11842(orthology-group)|efo:""Orphanet:84""|ensembl:ENSG00000116670.17(gene)|ensembl:ENST00000235310.7(transcript)|ensembl:ENST00000376667.7(transcript)|ensembl:ENST00000376692.9(transcript)|ensembl:ENST00000456915.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002208""(somatic diversification of immunoglobulins involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006302""(double-strand break repair)|go:""GO:0007015""(actin filament organization)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|rcsb pdb:6WS0|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016035""(zeta DNA polymerase complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0042772""(DNA damage response, signal transduction resulting in transcription)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051301""(cell division)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000678""(negative regulation of transcription regulatory region DNA binding)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|interpro:IPR045091|mint:Q9UI95|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/06	rogid:Xi+lGjtCtERpBpNdPvEPyVtkQlA83334	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	intact-crc:710C5183FBFE05DC|rigid:mo1NSwnqmsBgvMW9SA+QggPUKSg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7DB77	uniprotkb:P61601	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-749635|uniprotkb:P29554|uniprotkb:Q8IYC3|uniprotkb:Q9H0W2|ensembl:ENSP00000220931.6|ensembl:ENSP00000310587.3|ensembl:ENSP00000379256.1|ensembl:ENSP00000428105.1|ensembl:ENSP00000430476.1	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:ncald_human(display_long)|uniprotkb:NCALD(gene name)|psi-mi:NCALD(display_short)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039508|imex:IM-23549-43	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_001035714.1|refseq:NP_001035715.1|refseq:NP_001035716.1|refseq:NP_001035717.1|refseq:NP_001035718.1|refseq:NP_001035719.1|refseq:NP_001035720.1|refseq:NP_114430.2|ensembl:ENSG00000104490.18(gene)|ensembl:ENST00000220931.11(transcript)|ensembl:ENST00000311028.4(transcript)|ensembl:ENST00000395923.5(transcript)|ensembl:ENST00000519508.6(transcript)|ensembl:ENST00000521599.5(transcript)|go:""GO:0003073""(regulation of systemic arterial blood pressure)|go:""GO:0003779""(actin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0015631""(tubulin binding)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0030130""(clathrin coat of trans-Golgi network vesicle)|go:""GO:0030276""(clathrin binding)|go:""GO:0043014""(alpha-tubulin binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:P61601|reactome:R-HSA-451308|refseq:XP_011515634.1|refseq:XP_011515635.1|refseq:XP_011515636.1|refseq:XP_011515637.1|refseq:XP_016869390.1|refseq:XP_016869391.1|panther:PTHR23055(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:1/KBd+bN0cMZa81XKSSGPxgQEzc9606	intact-crc:F555C48A82ACB234|rigid:NW9lpVQdfwALyaamEljTN/cqgoo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7DB76	uniprotkb:Q15599	intact:EBI-10039068|uniprotkb:Q7A9Q0|uniprotkb:A0A0H3JJD5|uniprotkb:A0A6M0JL37	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005.2|intact:EBI-15579694	psi-mi:q7db76_eco57(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:ECs_4562(orf name)	psi-mi:nhrf2_human(display_long)|uniprotkb:NHERF2(gene name)|psi-mi:NHERF2(display_short)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039081|imex:IM-23549-21	intact-miscore:0.57	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000492638.1|interpro:IPR004959(IpaB/EvcA)|refseq:NP_312589.1	"refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|panther:PTHR14191(orthology-group)|ensembl:ENSG00000065054.14(gene)|ensembl:ENST00000424542.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031799""(type 2 metabotropic glutamate receptor binding)|go:""GO:0031800""(type 3 metabotropic glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300(""Na(+)/H(+) exchange regulatory cofactor NHE-RF"")|interpro:IPR036034|interpro:IPR051067|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|dip:DIP-29093N"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:xO5ymWP2ug1VLyxelIaeen+24gM83334	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	intact-crc:BDA090412E07CDF7|rigid:ZFQ2ER4vDnTY3j2m0nmj7IjFPoQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NWS0	uniprotkb:Q8XA11	intact:EBI-357318|intact:EBI-748162|uniprotkb:B4DGN7|uniprotkb:B4E2X7|uniprotkb:Q9BVL0|ensembl:ENSP00000262265.4|ensembl:ENSP00000470445.1	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	psi-mi:pihd1_human(display_long)|uniprotkb:PIH1D1(gene name)|psi-mi:PIH1D1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17 homolog(gene name synonym)	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039014|imex:IM-23549-17	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060386.1|ensembl:ENSG00000104872.12(gene)|ensembl:ENST00000262265.10(transcript)|ensembl:ENST00000596049.5(transcript)|go:""GO:0000492""(box C/D snoRNP assembly)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006364""(rRNA processing)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0042393""(histone binding)|go:""GO:0048254""(snoRNA localization)|go:""GO:0050821""(protein stabilization)|go:""GO:0051117""(ATPase binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0070761""(pre-snoRNP complex)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097255""(R2TP complex)|go:""GO:0140566""(histone reader activity)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1902661""(positive regulation of glucose mediated signaling pathway)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1905669""(TORC1 complex assembly)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR012981(Nop17p)|interpro:IPR041442|interpro:IPR050734|mint:Q9NWS0|rcsb pdb:4PSF|rcsb pdb:4PSI|rcsb pdb:6GXZ|rcsb pdb:7AVC|rcsb pdb:8BDU|panther:PTHR22997(orthology-group)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:lugKS0BlzZYpMZn/7LFHODnFk0Q9606	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	intact-crc:9CAC94FFD36274B6|rigid:BOQdiS8j1wlzSuTh62U6lJGzrzo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5JVF3	uniprotkb:Q8XA11	intact:EBI-1051701|uniprotkb:A6NK09|uniprotkb:Q3ZCX1|uniprotkb:Q5TC57|uniprotkb:Q5TC58|uniprotkb:Q9H7K1|uniprotkb:Q9HBZ7|uniprotkb:Q9NUK6|uniprotkb:Q9NVY1|uniprotkb:Q9NW44|uniprotkb:Q9NWH3|ensembl:ENSP00000337405.4|ensembl:ENSP00000364626.1|ensembl:ENSP00000364628.2	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	psi-mi:pcid2_human(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short)|uniprotkb:HT004(orf name)	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039010|imex:IM-23549-16	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001120674.1|refseq:NP_001120675.1|refseq:NP_060856.2|refseq:NP_001245142.1|refseq:NP_001307584.1|refseq:NP_001307585.1|refseq:NP_001307586.1|refseq:NP_001307589.1|refseq:XP_016876153.1|dip:DIP-50497N|ensembl:ENSG00000126226.22(gene)|ensembl:ENST00000337344.9(transcript)|ensembl:ENST00000375477.5(transcript)|ensembl:ENST00000375479.6(transcript)|go:""GO:0000973""(post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0015031""(protein transport)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0044615""(nuclear pore nuclear basket)|go:""GO:0045579""(positive regulation of B cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048536""(spleen development)|go:""GO:0060633""(negative regulation of transcription initiation by RNA polymerase II)|go:""GO:0070390""(transcription export complex 2)|go:""GO:0070828""(heterochromatin organization)|go:""GO:0090267""(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:""GO:1905457""(negative regulation of lymphoid progenitor cell differentiation)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR045114|mint:Q5JVF3|rcsb pdb:3T5X|panther:PTHR12732(orthology-group)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	intact-crc:76943587E0E5963A|rigid:yf4oiTDQLpGkLd2aLg559p06zR8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P05204	uniprotkb:Q8XAL7	intact:EBI-1758689|uniprotkb:Q0VGD5|uniprotkb:Q6FGI5|uniprotkb:Q96C64|ensembl:ENSP00000355228.5	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:hmgn2_human(display_long)|uniprotkb:HMGN2(gene name)|psi-mi:HMGN2(display_short)|uniprotkb:HMG17(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10040179|imex:IM-23549-62	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005508.1|ensembl:ENSG00000198830.13(gene)|ensembl:ENST00000361427.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05204|panther:PTHR23087(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:j8Khsp7BUJh0L9SicpVNR8LP6ZU9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:00F245B1E25397F5|rigid:PF/SuX8AHZOi79VBEk4FrlTd2hE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IY31	uniprotkb:Q8XB62	intact:EBI-744203|uniprotkb:Q5GLZ2|uniprotkb:Q9BUG5|intact:EBI-2561300|uniprotkb:J3QL09|ensembl:ENSP00000378809.3|ensembl:ENSP00000463138.1	intact:EBI-10038787|uniprotkb:Q7ACX7|uniprotkb:A0A0H3JG75|uniprotkb:A0A6M0JSQ6	psi-mi:ift20_human(display_long)|uniprotkb:IFT20(gene name)|psi-mi:IFT20(display_short)	psi-mi:q8xb62_eco57(display_long)|uniprotkb:espJ(gene name)|psi-mi:espJ(display_short)|uniprotkb:ECs_2714(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038810|imex:IM-23549-8	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001254706.1|refseq:NP_001254707.1|refseq:NP_777547.1|refseq:NP_001254703.1|refseq:NP_001254704.1|refseq:NP_001254705.1|ensembl:ENSG00000109083.14(gene)|ensembl:ENST00000395418.8(transcript)|ensembl:ENST00000585313.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001736""(establishment of planar polarity)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001822""(kidney development)|go:""GO:0002046""(opsin binding)|go:""GO:0002177""(manchette)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005902""(microvillus)|go:""GO:0005929""(cilium)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008542""(visual learning)|go:""GO:0030990""(intraciliary transport particle)|go:""GO:0030992""(intraciliary transport particle B)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031514""(motile cilium)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0032420""(stereocilium)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0035720""(intraciliary anterograde transport)|go:""GO:0035845""(photoreceptor cell outer segment organization)|go:""GO:0036064""(ciliary basal body)|go:""GO:0036372""(opsin transport)|go:""GO:0043005""(neuron projection)|go:""GO:0044292""(dendrite terminus)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045724""(positive regulation of cilium assembly)|go:""GO:0051642""(centrosome localization)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060122""(inner ear receptor cell stereocilium organization)|go:""GO:0060271""(cilium assembly)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0061351""(neural precursor cell proliferation)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090102""(cochlea development)|go:""GO:0097542""(ciliary tip)|go:""GO:0097546""(ciliary base)|go:""GO:0097730""(non-motile cilium)|go:""GO:1902017""(regulation of cilium assembly)|go:""GO:1902636""(kinociliary basal body)|go:""GO:2000583""(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR028172|mint:Q8IY31|reactome:R-HSA-5620924|panther:PTHR31978(orthology-group)"	refseq:WP_000022458.1|interpro:IPR015226(AvrPphF ORF-2)|refseq:NP_310741.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:/sGgagcq0b/YoxjD4Psc7D6jY2Q9606	rogid:pwnhf6VxgSKHIqJxvoUGpqp7Iu083334	intact-crc:22A323EC6E51822A|rigid:GOx3vrhYE3HmDkzvD5qrQmzRvCU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43924	uniprotkb:Q7DB77	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600.4	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039512|imex:IM-23549-44	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000156973.14(gene)|ensembl:ENST00000287600.9(transcript)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005929""(cilium)|go:""GO:0007601""(visual perception)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|rcsb pdb:7PAC|rcsb pdb:7PAD|rcsb pdb:7PAE|rcsb pdb:7Q9Q|rcsb pdb:7Q9R|rcsb pdb:7Q9S|rcsb pdb:7Q9U|rcsb pdb:7QF9|rcsb pdb:7QJK|reactome:R-HSA-5624958|reactome:R-HSA-9648002|refseq:NP_001277947.1|refseq:NP_002592.1|efo:""Orphanet:2754""|efo:""Orphanet:475""|dip:DIP-36660N|panther:PTHR12976(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:973BD03D588C513C|rigid:nSx3EzGVFU/94uLHaqDzzak+8G8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XBX8	uniprotkb:P19388	intact:EBI-10039153|uniprotkb:Q7AAV0|uniprotkb:A0A0H3JHS6|uniprotkb:A0A6M0JF43	intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739.1|ensembl:ENSP00000478303.1|ensembl:ENSP00000485021.1	psi-mi:nleb1_eco57(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:ECs3857(locus name)	psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039185|imex:IM-23549-28	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000953022.1|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|refseq:NP_311884.1"	"refseq:NP_002686.2|ensembl:ENSG00000099817.12(gene)|ensembl:ENST00000586746.5(transcript)|ensembl:ENST00000612655.4(transcript)|ensembl:ENST00000615234.5(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005665""(RNA polymerase II, core complex)|go:""GO:0005666""(RNA polymerase III complex)|go:""GO:0005736""(RNA polymerase I complex)|go:""GO:0005829""(cytosol)|go:""GO:0006362""(transcription elongation by RNA polymerase I)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0042797""(tRNA transcription by RNA polymerase III)|go:""GO:0050821""(protein stabilization)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR035913|interpro:IPR036710|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7FJI|rcsb pdb:7FJJ|rcsb pdb:7LBM|rcsb pdb:7OB9|rcsb pdb:7OBA|rcsb pdb:7OBB|rcsb pdb:7VBA|rcsb pdb:7VBB|rcsb pdb:7VBC|rcsb pdb:8A43|rcsb pdb:8ITY|rcsb pdb:8IUE|rcsb pdb:8IUH|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-56N|panther:PTHR10535(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/03/27	rogid:s08ivrjNoMdHHNcIwH+V7ZobNOQ83334	rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606	intact-crc:3348787B7A64DCBF|rigid:EGGLTS8gvnQ9KWaTXgG0OZXT9ZM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BYM8	uniprotkb:Q8XC86	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632.6	intact:EBI-10038594|uniprotkb:Q7A9Q6|uniprotkb:A0A0H3JJC8|uniprotkb:A0A6M0JLD0	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:q8xc86_eco57(display_long)|uniprotkb:espB(gene name)|psi-mi:espB(display_short)|uniprotkb:ECs_4554(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038604|imex:IM-23549-1	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-47737N|ensembl:ENSG00000125826.22(gene)|ensembl:ENST00000356286.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0071797""(LUBAC complex)|go:""GO:0097039""(protein linear polyubiquitination)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1990757""(ubiquitin ligase activator activity)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|interpro:IPR047557|interpro:IPR047558|interpro:IPR047559|interpro:IPR051628|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|rcsb pdb:7V8E|rcsb pdb:7YUI|rcsb pdb:7YUJ|rcsb pdb:8BVL|rcsb pdb:8EAZ|rcsb pdb:8K6Q|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|refseq:NP_006453.1|refseq:NP_112506.2|efo:""Orphanet:329173""|efo:""Orphanet:397937""|panther:PTHR22770(orthology-group)"	refseq:WP_001092000.1|interpro:IPR008611(Enterobacterial EspB)|refseq:NP_312581.1	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/03/26	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	rogid:9cKWrLKb1089HnklaM95O3OLdTQ83334	intact-crc:BCF4854CEA6E6936|rigid:Cr3FpGA3wpV+Ewb6qFIbZAB7y2g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7DB77	uniprotkb:O75716	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964.2|ensembl:ENSP00000386928.3	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039518|imex:IM-23549-45	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_001008910.1|ensembl:ENSG00000115661.14(gene)|ensembl:ENST00000396738.7(transcript)|ensembl:ENST00000409638.7(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR052239|mint:O75716|rcsb pdb:2BUJ|refseq:NP_001317142.1|dip:DIP-29598N|panther:PTHR45998(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/24	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606	intact-crc:502DCC019B41C818|rigid:PtFZg2M0P8t6pPCwD5zeyLdixIc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XAL7	uniprotkb:Q96Q11	intact:EBI-10039292|uniprotkb:Q7AEM9	intact:EBI-2839106|uniprotkb:Q9Y362|uniprotkb:Q9BS97|uniprotkb:Q8ND57|uniprotkb:A8K2Z6|uniprotkb:B7WP13|uniprotkb:C9JKA2|ensembl:ENSP00000251607.6|ensembl:ENSP00000415100.1|ensembl:ENSP00000513700.1|ensembl:ENSP00000513701.1|ensembl:ENSP00000513705.1	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	psi-mi:trnt1_human(display_long)|uniprotkb:TRNT1(gene name)|psi-mi:TRNT1(display_short)|uniprotkb:Mitochondrial tRNA nucleotidyl transferase, CCA-adding(gene name synonym)|uniprotkb:mt CCA-adding enzyme(gene name synonym)|uniprotkb:mt tRNA CCA-diphosphorylase(gene name synonym)|uniprotkb:mt tRNA CCA-pyrophosphorylase(gene name synonym)|uniprotkb:mt tRNA adenylyltransferase(gene name synonym)|uniprotkb:CGI-47(orf name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039438|imex:IM-23549-36	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	"efo:""Orphanet:369861""|ensembl:ENSG00000072756.18(gene)|ensembl:ENST00000251607.11(transcript)|ensembl:ENST00000434583.5(transcript)|ensembl:ENST00000698406.1(transcript)|ensembl:ENST00000698408.1(transcript)|ensembl:ENST00000698412.1(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0001680""(tRNA 3'-terminal CCA addition)|go:""GO:0004810""(CCA tRNA nucleotidyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0034062""(5'-3' RNA polymerase activity)|go:""GO:0042780""(tRNA 3'-end processing)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0106354""(tRNA surveillance)|go:""GO:0160016""(CCACCA tRNA nucleotidyltransferase activity)|go:""GO:1990180""(mitochondrial tRNA 3'-end processing)|interpro:IPR002646(Polynucleotide adenylyltransferase region)|interpro:IPR032828|interpro:IPR043519|interpro:IPR050264|rcsb pdb:1OU5|rcsb pdb:4X4W|rcsb pdb:8CBM|reactome:R-HSA-6784531|reactome:R-HSA-6785470|refseq:NP_001289875.1|refseq:NP_886552.2|refseq:XP_011532078.1|refseq:XP_011532079.1|refseq:XP_011532080.1|panther:PTHR46173(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	rogid:COxi4PrWifNnDPkI+lile/5kD9I9606	intact-crc:404499C777F92018|rigid:2fkFc3ICDs1nvcYYs5P7hqnjtmI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UM19	uniprotkb:Q7DB77	intact:EBI-744820|uniprotkb:Q5TG97|uniprotkb:Q8N611|uniprotkb:B2R5U2|uniprotkb:D3DPU1|ensembl:ENSP00000361935.3|ensembl:ENSP00000481834.1	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:hpcl4_human(display_long)|uniprotkb:HPCAL4(gene name)|psi-mi:HPCAL4(display_short)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039504|imex:IM-23549-42	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057341.1|refseq:NP_001269325.1|refseq:XP_016856936.1|ensembl:ENSG00000116983.13(gene)|ensembl:ENST00000372844.8(transcript)|ensembl:ENST00000617690.2(transcript)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0007417""(central nervous system development)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0019904""(protein domain specific binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:Q9UM19|panther:PTHR23055(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:+2KFQ7WO9Kyn14ySKaEmm1V6pRM9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:AC1DE0502BCA4901|rigid:1IogbQyoEvXFZXTvTXzoGXPvL0A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XA11	uniprotkb:P49759	intact:EBI-10038919|uniprotkb:Q7AHS4|uniprotkb:A0A0H3JC43	intact:EBI-473775|uniprotkb:Q8N5V8|uniprotkb:Q0P694|intact:EBI-2622912|uniprotkb:B4DFW7|ensembl:ENSP00000326830.4	psi-mi:q8xa11_eco57(display_long)|uniprotkb:espY1(gene name)|psi-mi:espY1(display_short)|uniprotkb:ECs_0061(orf name)	psi-mi:clk1_human(display_long)|uniprotkb:CDC-like kinase 1(gene name synonym)|uniprotkb:CLK1(gene name)|psi-mi:CLK1(display_short)|uniprotkb:CLK(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038970|imex:IM-23549-14	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_001304001.1|refseq:NP_308088.1	"refseq:NP_004062.2|refseq:NP_001155879.1|panther:PTHR45646(orthology-group)|rcsb pdb:6R6E|ensembl:ENSG00000013441.17(gene)|ensembl:ENST00000321356.9(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004712""(protein serine/threonine/tyrosine kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR051175|mint:P49759|rcsb pdb:1Z57|rcsb pdb:2VAG|rcsb pdb:5J1V|rcsb pdb:5J1W|rcsb pdb:5X8I|rcsb pdb:6FT8|rcsb pdb:6FT9|rcsb pdb:6FYO|rcsb pdb:6G33|rcsb pdb:6I5H|rcsb pdb:6I5I|rcsb pdb:6I5K|rcsb pdb:6I5L|rcsb pdb:6KHD|rcsb pdb:6Q8K|rcsb pdb:6Q8P|rcsb pdb:6QTY|rcsb pdb:6R3D|rcsb pdb:6R6X|rcsb pdb:6R8J|rcsb pdb:6RAA|rcsb pdb:6TW2|rcsb pdb:6YTA|rcsb pdb:6YTD|rcsb pdb:6YTE|rcsb pdb:6YTG|rcsb pdb:6YTI|rcsb pdb:6Z4Z|rcsb pdb:6Z50|rcsb pdb:6ZLN|rcsb pdb:7AK3|rcsb pdb:7O9Y|rcsb pdb:7OA0|rcsb pdb:7OPG|rcsb pdb:8P04|rcsb pdb:8P08"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:Wcj5te52gWAr/zHWrvjervg1eqs83334	rogid:HUyYLfLTfZHyTdtTNdbR/HPBloM9606	intact-crc:5A3CD418A8E4DEE1|rigid:V+VYmyTEy8pcXOEJ4ODb1NiW6cY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XC86	uniprotkb:O75716	intact:EBI-10038594|uniprotkb:Q7A9Q6|uniprotkb:A0A0H3JJC8|uniprotkb:A0A6M0JLD0	intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964.2|ensembl:ENSP00000386928.3	psi-mi:q8xc86_eco57(display_long)|uniprotkb:espB(gene name)|psi-mi:espB(display_short)|uniprotkb:ECs_4554(orf name)	psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038684|imex:IM-23549-2	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001092000.1|interpro:IPR008611(Enterobacterial EspB)|refseq:NP_312581.1	"refseq:NP_001008910.1|ensembl:ENSG00000115661.14(gene)|ensembl:ENST00000396738.7(transcript)|ensembl:ENST00000409638.7(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR052239|mint:O75716|rcsb pdb:2BUJ|refseq:NP_001317142.1|dip:DIP-29598N|panther:PTHR45998(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/24	rogid:9cKWrLKb1089HnklaM95O3OLdTQ83334	rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606	intact-crc:7C5387F79C263648|rigid:TWTXO50+iq2Mr2haSEv0la8mxI0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XAL7	uniprotkb:P55211	intact:EBI-10039292|uniprotkb:Q7AEM9	intact:EBI-516799|uniprotkb:O95348|uniprotkb:Q92852|uniprotkb:Q9BQ62|uniprotkb:Q9UEQ3|uniprotkb:Q9UIJ8|uniprotkb:Q53Y70|uniprotkb:Q5JRU9|uniprotkb:Q5UGI1|uniprotkb:B4E1A3|ensembl:ENSP00000330237.5	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	psi-mi:casp9_human(display_long)|uniprotkb:ICE-like apoptotic protease 6(gene name synonym)|uniprotkb:Apoptotic protease Mch-6(gene name synonym)|uniprotkb:Apoptotic protease-activating factor 3(gene name synonym)|uniprotkb:CASP9(gene name)|psi-mi:CASP9(display_short)|uniprotkb:MCH6(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039290|imex:IM-23549-32	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	"refseq:NP_001264983.1|refseq:NP_001220.2|refseq:NP_127463.2|refseq:XP_005246071.1|ensembl:ENSG00000132906.18(gene)|ensembl:ENST00000333868.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001822""(kidney development)|go:""GO:0002931""(response to ischemia)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008233""(peptidase activity)|go:""GO:0008303""(caspase complex)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0016485""(protein processing)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030220""(platelet formation)|go:""GO:0032025""(response to cobalt ion)|go:""GO:0032355""(response to estradiol)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034349""(glial cell apoptotic process)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043293""(apoptosome)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044346""(fibroblast apoptotic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051604""(protein maturation)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0071887""(leukocyte apoptotic process)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR011600(Peptidase C14, caspase catalytic)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR042147|mint:P55211|rcsb pdb:1JXQ|rcsb pdb:1NW9|rcsb pdb:2AR9|rcsb pdb:3D9T|rcsb pdb:3V3K|rcsb pdb:3YGS|rcsb pdb:4RHW|rcsb pdb:5JUY|rcsb pdb:5WVC|rcsb pdb:5WVE|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-168638|reactome:R-HSA-198323|reactome:R-HSA-418889|reactome:R-HSA-5674400|reactome:R-HSA-9627069|panther:PTHR10454(orthology-group)|dip:DIP-27625N"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	rogid:IYW59Vh17AEnXa6/wLpkIPNE0Bo9606	intact-crc:1ECBFB40BC02C5CA|rigid:7k9kmTQrmSBvIMvcleDJFlJsRMU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7DB77	uniprotkb:P37235	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-749311|uniprotkb:Q969S5|ensembl:ENSP00000310749.3|ensembl:ENSP00000371184.3|ensembl:ENSP00000478231.1|ensembl:ENSP00000482993.1|ensembl:ENSP00000483786.1	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:hpcl1_human(display_long)|uniprotkb:Visinin-like protein 3(gene name synonym)|uniprotkb:Calcium-binding protein BDR-1(gene name synonym)|uniprotkb:HLP2(gene name synonym)|uniprotkb:HPCAL1(gene name)|psi-mi:HPCAL1(display_short)|uniprotkb:BDR1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039499|imex:IM-23549-41	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_002140.2|refseq:NP_602293.1|refseq:NP_001245286.1|refseq:NP_001245287.1|refseq:NP_001245288.1|refseq:XP_005246217.1|refseq:XP_005246218.1|refseq:XP_005246219.1|refseq:XP_005246220.1|refseq:XP_016859439.1|ensembl:ENSG00000115756.13(gene)|ensembl:ENST00000307845.8(transcript)|ensembl:ENST00000381765.7(transcript)|ensembl:ENST00000613496.4(transcript)|ensembl:ENST00000620771.4(transcript)|ensembl:ENST00000622018.4(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:P37235|rcsb pdb:5T7C|refseq:XP_011508648.1|refseq:XP_011508649.1|refseq:XP_011508650.1|refseq:XP_016859440.1|refseq:XP_016859441.1|refseq:XP_016859442.1|panther:PTHR23055(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:oK04sIDCtghEOWIBNQ75bR34+2o9606	intact-crc:2451DF341B1E4F30|rigid:1cwDS9Ro06Jrm9ll7Abp4YUxFYM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XBX8	uniprotkb:P55039	intact:EBI-10039153|uniprotkb:Q7AAV0|uniprotkb:A0A0H3JHS6|uniprotkb:A0A6M0JF43	intact:EBI-750565|uniprotkb:Q9BWB2|uniprotkb:B2R8G5|uniprotkb:Q53Y50|ensembl:ENSP00000225729.3	psi-mi:nleb1_eco57(display_long)|uniprotkb:nleB1(gene name)|psi-mi:nleB1(display_short)|uniprotkb:Non-LEE-encoded type III effector B1(gene name synonym)|uniprotkb:ECs3857(locus name)	psi-mi:drg2_human(display_long)|uniprotkb:DRG2(gene name)|psi-mi:DRG2(display_short)|uniprotkb:Translation factor GTPase DRG2(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039161|imex:IM-23549-26	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000953022.1|go:""GO:0005576""(extracellular region)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0052038""(symbiont-mediated perturbation of host intracellular transport)|go:""GO:0090729""(toxin activity)|go:""GO:0106362""(protein-arginine N-acetylglucosaminyltransferase activity)|refseq:NP_311884.1"	"refseq:NP_001379.1|ensembl:ENSG00000108591.10(gene)|ensembl:ENST00000225729.8(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|interpro:IPR045001|reactome:R-HSA-9629569|panther:PTHR43127(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:s08ivrjNoMdHHNcIwH+V7ZobNOQ83334	rogid:9bgX8C0kJmO5KdaYHU+vAmDCTPo9606	intact-crc:88F1A944A46204A9|rigid:dD+KM+yBSkP8/jr7kNRM9Vf95Rw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7DB85	uniprotkb:Q8WV41	intact:EBI-10038700|uniprotkb:Q7A9R0|uniprotkb:A0A0H3JQD8	intact:EBI-2481535|uniprotkb:B1NM17|ensembl:ENSP00000311427.6	psi-mi:q7db85_eco57(display_long)|uniprotkb:espF(gene name)|psi-mi:espF(display_short)|uniprotkb:ECs_4550(orf name)	psi-mi:snx33_human(display_long)|uniprotkb:SNX33(gene name)|psi-mi:SNX33(display_short)|uniprotkb:SH3PX3(gene name synonym)|uniprotkb:SH3PXD3C(gene name synonym)|uniprotkb:SNX30(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10038720|imex:IM-23549-4	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006891(EspF protein)|refseq:WP_000931693.1|refseq:NP_312577.1	"refseq:NP_695003.1|refseq:NP_001305075.1|ensembl:ENSG00000173548.9(gene)|ensembl:ENST00000308527.6(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0007032""(endosome organization)|go:""GO:0016020""(membrane)|go:""GO:0016197""(endosomal transport)|go:""GO:0017038""(protein import)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0042802""(identical protein binding)|go:""GO:0044351""(macropinocytosis)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0051044""(positive regulation of membrane protein ectodomain proteolysis)|go:""GO:0097320""(plasma membrane tubulation)|go:""GO:2000009""(negative regulation of protein localization to cell surface)|go:""GO:2000010""(positive regulation of protein localization to cell surface)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR036028|interpro:IPR036871|interpro:IPR037427|mint:Q8WV41|rcsb pdb:4AKV|panther:PTHR45827(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:Xi+lGjtCtERpBpNdPvEPyVtkQlA83334	rogid:rhvspe+J40o9M1MJtpUIyeQFLRs9606	intact-crc:A0CC49853790D98C|rigid:EJWElMHIfoLZPiYqkhIBXyoQTjI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UQB8	uniprotkb:Q7DB77	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338.6	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Brain-specific angiogenesis inhibitor 1-associated protein 2(gene name synonym)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039889|imex:IM-23549-53	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000175866.16(gene)|ensembl:ENST00000321300.10(transcript)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001726""(ruffle)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0007409""(axonogenesis)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016358""(dendrite development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030141""(secretory granule)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030175""(filopodium)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043198""(dendritic shaft)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060076""(excitatory synapse)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0061845""(neuron projection branch point)|go:""GO:0061846""(dendritic spine cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:2000463""(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|panther:PTHR14206(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/12/31	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:38474E7B8688808C|rigid:+FInGdMTTBxacaG2SJDoullzsRQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8XAJ5	uniprotkb:A2A2Y4	intact:EBI-10039107|uniprotkb:Q7AEN2|uniprotkb:A0A0H3JEG7|uniprotkb:A0A6M0JSD1	intact:EBI-6911547|uniprotkb:Q8N9L2|uniprotkb:Q53EP2|uniprotkb:Q5JV59|uniprotkb:A8MQB0|uniprotkb:B4DN14|uniprotkb:Q8IZ44|uniprotkb:Q5VZA1|uniprotkb:Q8N3Y5|uniprotkb:Q86WP8|ensembl:ENSP00000303508.3	psi-mi:q8xaj5_eco57(display_long)|uniprotkb:nleA/espI(gene name)|psi-mi:nleA/espI(display_short)|uniprotkb:ECs_1812(orf name)	psi-mi:frmd3_human(display_long)|uniprotkb:Band 4.1-like protein 4O(gene name synonym)|uniprotkb:EPB41L4O(gene name synonym)|uniprotkb:Ovary type protein 4.1(gene name synonym)|uniprotkb:FRMD3(gene name)|psi-mi:FRMD3(display_short)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039131|imex:IM-23549-23	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001025672.1|refseq:NP_309839.1	"refseq:NP_001231888.1|refseq:NP_001231889.1|refseq:NP_001231890.1|refseq:NP_001231891.1|refseq:NP_777598.3|ensembl:ENSG00000172159.16(gene)|ensembl:ENST00000304195.8(transcript)|go:""GO:0005856""(cytoskeleton)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0016020""(membrane)|go:""GO:0031032""(actomyosin structure organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|panther:PTHR23280(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2024/11/14	rogid:ZP/LIKGH/FXS6bNOJyNxNGXCH8883334	rogid:mhyjQ1Yy8dmn8JseI7ehX//yySw9606	intact-crc:F725F0B4C35868DB|rigid:kms1NOgh7ZGGd3jJyLXtwhDJQr0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7DB77	uniprotkb:P49407	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581.2	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039479|imex:IM-23549-39	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_004032.2|refseq:NP_064647.1|dip:DIP-29979N|ensembl:ENSG00000137486.17(gene)|ensembl:ENST00000420843.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002031""(G protein-coupled receptor internalization)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0015031""(protein transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031143""(pseudopodium)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031701""(angiotensin receptor binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:1990763""(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|rcsb pdb:7R0C|rcsb pdb:7R0J|rcsb pdb:7SRS|rcsb pdb:8AS2|rcsb pdb:8AS3|rcsb pdb:8AS4|rcsb pdb:8JRV|rcsb pdb:8WRZ|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9839389|panther:PTHR11792(orthology-group)|ensembl:ENST00000360025.7|ensembl:ENSP00000353124.3|ensembl:ENSP00000409581.2"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/03/24	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606	intact-crc:946217BC87DBD59C|rigid:egVpT0wXvb3+UoIaPOCReuZ+1zM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7DB77	uniprotkb:Q9UHR4	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-2483278|uniprotkb:A4D268|uniprotkb:Q75L21|uniprotkb:Q75L22|uniprotkb:Q96CV4|uniprotkb:Q9H5F5|uniprotkb:Q9Y2M8|ensembl:ENSP00000005260.8	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:bi2l1_human(display_long)|uniprotkb:BAIAP2L1(gene name)|psi-mi:BAIAP2L1(display_short)|uniprotkb:IRTKS(gene name synonym)|uniprotkb:Insulin receptor tyrosine kinase substrate(gene name synonym)|uniprotkb:Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039484|imex:IM-23549-40	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_061330.2|dip:DIP-53820N|ensembl:ENSG00000006453.14(gene)|ensembl:ENST00000005260.9(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030060|interpro:IPR035592|interpro:IPR036028|mint:Q9UHR4|rcsb pdb:2KXC|rcsb pdb:2LNH|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR14206(orthology-group)"	-	-	-	figure legend:Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2014/12/10	2025/01/27	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:ig7xSOv8h6Y4vYE0/n228+ZLWaM9606	intact-crc:1DF19F5B9BFC41B5|rigid:VE0c/Qjb0IzvfXI7VcEea+480MY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61601	uniprotkb:Q7DB77	intact:EBI-749635|uniprotkb:P29554|uniprotkb:Q8IYC3|uniprotkb:Q9H0W2|ensembl:ENSP00000220931.6|ensembl:ENSP00000310587.3|ensembl:ENSP00000379256.1|ensembl:ENSP00000428105.1|ensembl:ENSP00000430476.1	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:ncald_human(display_long)|uniprotkb:NCALD(gene name)|psi-mi:NCALD(display_short)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039836|imex:IM-23549-50	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035714.1|refseq:NP_001035715.1|refseq:NP_001035716.1|refseq:NP_001035717.1|refseq:NP_001035718.1|refseq:NP_001035719.1|refseq:NP_001035720.1|refseq:NP_114430.2|ensembl:ENSG00000104490.18(gene)|ensembl:ENST00000220931.11(transcript)|ensembl:ENST00000311028.4(transcript)|ensembl:ENST00000395923.5(transcript)|ensembl:ENST00000519508.6(transcript)|ensembl:ENST00000521599.5(transcript)|go:""GO:0003073""(regulation of systemic arterial blood pressure)|go:""GO:0003779""(actin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0015631""(tubulin binding)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0030130""(clathrin coat of trans-Golgi network vesicle)|go:""GO:0030276""(clathrin binding)|go:""GO:0043014""(alpha-tubulin binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:P61601|reactome:R-HSA-451308|refseq:XP_011515634.1|refseq:XP_011515635.1|refseq:XP_011515636.1|refseq:XP_011515637.1|refseq:XP_016869390.1|refseq:XP_016869391.1|panther:PTHR23055(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Fig 5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2014/12/10	2024/11/14	rogid:1/KBd+bN0cMZa81XKSSGPxgQEzc9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:74030D211DCFD86D|rigid:NW9lpVQdfwALyaamEljTN/cqgoo	false	renilla luciferase protein tag:?-?	protein a tag:?-?	-	-	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"
uniprotkb:O43924	uniprotkb:Q7DB77	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600.4	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039853|imex:IM-23549-51	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000156973.14(gene)|ensembl:ENST00000287600.9(transcript)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005929""(cilium)|go:""GO:0007601""(visual perception)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|rcsb pdb:7PAC|rcsb pdb:7PAD|rcsb pdb:7PAE|rcsb pdb:7Q9Q|rcsb pdb:7Q9R|rcsb pdb:7Q9S|rcsb pdb:7Q9U|rcsb pdb:7QF9|rcsb pdb:7QJK|reactome:R-HSA-5624958|reactome:R-HSA-9648002|refseq:NP_001277947.1|refseq:NP_002592.1|efo:""Orphanet:2754""|efo:""Orphanet:475""|dip:DIP-36660N|panther:PTHR12976(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Fig. 5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2014/12/10	2024/11/14	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:A33E3D267B019DFE|rigid:nSx3EzGVFU/94uLHaqDzzak+8G8	false	renilla luciferase protein tag:?-?	protein a tag:?-?	-	-	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"
uniprotkb:Q7DB77	uniprotkb:Q9UM19	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-744820|uniprotkb:Q5TG97|uniprotkb:Q8N611|uniprotkb:B2R5U2|uniprotkb:D3DPU1|ensembl:ENSP00000361935.3|ensembl:ENSP00000481834.1	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:hpcl4_human(display_long)|uniprotkb:HPCAL4(gene name)|psi-mi:HPCAL4(display_short)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039832|imex:IM-23549-49	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_057341.1|refseq:NP_001269325.1|refseq:XP_016856936.1|ensembl:ENSG00000116983.13(gene)|ensembl:ENST00000372844.8(transcript)|ensembl:ENST00000617690.2(transcript)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0007417""(central nervous system development)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0019904""(protein domain specific binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:Q9UM19|panther:PTHR23055(orthology-group)"	-	-	-	figure legend:Fig. 5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2014/12/10	2024/11/14	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:+2KFQ7WO9Kyn14ySKaEmm1V6pRM9606	intact-crc:153B080E9987E7B0|rigid:1IogbQyoEvXFZXTvTXzoGXPvL0A	false	protein a tag:?-?	renilla luciferase protein tag:?-?	-	-	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"
uniprotkb:O75716	uniprotkb:Q7DB77	intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964.2|ensembl:ENSP00000386928.3	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039863|imex:IM-23549-52	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001008910.1|ensembl:ENSG00000115661.14(gene)|ensembl:ENST00000396738.7(transcript)|ensembl:ENST00000409638.7(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR052239|mint:O75716|rcsb pdb:2BUJ|refseq:NP_001317142.1|dip:DIP-29598N|panther:PTHR45998(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:Fig. 5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2014/12/10	2025/01/24	rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:DD8F3663CD9592E7|rigid:PtFZg2M0P8t6pPCwD5zeyLdixIc	false	renilla luciferase protein tag:?-?	protein a tag:?-?	-	-	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"
uniprotkb:Q7DB77	uniprotkb:P37235	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-749311|uniprotkb:Q969S5|ensembl:ENSP00000310749.3|ensembl:ENSP00000371184.3|ensembl:ENSP00000478231.1|ensembl:ENSP00000482993.1|ensembl:ENSP00000483786.1	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:hpcl1_human(display_long)|uniprotkb:Visinin-like protein 3(gene name synonym)|uniprotkb:Calcium-binding protein BDR-1(gene name synonym)|uniprotkb:HLP2(gene name synonym)|uniprotkb:HPCAL1(gene name)|psi-mi:HPCAL1(display_short)|uniprotkb:BDR1(gene name synonym)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039826|imex:IM-23549-48	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_002140.2|refseq:NP_602293.1|refseq:NP_001245286.1|refseq:NP_001245287.1|refseq:NP_001245288.1|refseq:XP_005246217.1|refseq:XP_005246218.1|refseq:XP_005246219.1|refseq:XP_005246220.1|refseq:XP_016859439.1|ensembl:ENSG00000115756.13(gene)|ensembl:ENST00000307845.8(transcript)|ensembl:ENST00000381765.7(transcript)|ensembl:ENST00000613496.4(transcript)|ensembl:ENST00000620771.4(transcript)|ensembl:ENST00000622018.4(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:P37235|rcsb pdb:5T7C|refseq:XP_011508648.1|refseq:XP_011508649.1|refseq:XP_011508650.1|refseq:XP_016859440.1|refseq:XP_016859441.1|refseq:XP_016859442.1|panther:PTHR23055(orthology-group)"	-	-	-	figure legend:Fig. 5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2014/12/10	2024/11/14	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:oK04sIDCtghEOWIBNQ75bR34+2o9606	intact-crc:2AD9B3F4DDA80BF5|rigid:1cwDS9Ro06Jrm9ll7Abp4YUxFYM	false	protein a tag:?-?	renilla luciferase protein tag:?-?	-	-	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"
uniprotkb:Q7DB77	uniprotkb:Q9UQB8	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338.6	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Brain-specific angiogenesis inhibitor 1-associated protein 2(gene name synonym)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039893|imex:IM-23549-54	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"ensembl:ENSG00000175866.16(gene)|ensembl:ENST00000321300.10(transcript)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001726""(ruffle)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0007409""(axonogenesis)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016358""(dendrite development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030141""(secretory granule)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030175""(filopodium)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043198""(dendritic shaft)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060076""(excitatory synapse)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0061845""(neuron projection branch point)|go:""GO:0061846""(dendritic spine cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:2000463""(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|panther:PTHR14206(orthology-group)"	-	-	-	figure legend:Fig. 5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2014/12/10	2024/12/31	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	intact-crc:294212F4DE1928B6|rigid:+FInGdMTTBxacaG2SJDoullzsRQ	false	protein a tag:?-?	renilla luciferase protein tag:?-?	-	-	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"
uniprotkb:Q7DB77	uniprotkb:Q9UHR4	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-2483278|uniprotkb:A4D268|uniprotkb:Q75L21|uniprotkb:Q75L22|uniprotkb:Q96CV4|uniprotkb:Q9H5F5|uniprotkb:Q9Y2M8|ensembl:ENSP00000005260.8	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:bi2l1_human(display_long)|uniprotkb:BAIAP2L1(gene name)|psi-mi:BAIAP2L1(display_short)|uniprotkb:IRTKS(gene name synonym)|uniprotkb:Insulin receptor tyrosine kinase substrate(gene name synonym)|uniprotkb:Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1(gene name synonym)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039820|imex:IM-23549-47	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_061330.2|dip:DIP-53820N|ensembl:ENSG00000006453.14(gene)|ensembl:ENST00000005260.9(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030060|interpro:IPR035592|interpro:IPR036028|mint:Q9UHR4|rcsb pdb:2KXC|rcsb pdb:2LNH|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR14206(orthology-group)"	-	-	-	figure legend:Fig. 5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2014/12/10	2025/01/27	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:ig7xSOv8h6Y4vYE0/n228+ZLWaM9606	intact-crc:ADD19FCC85BFA97C|rigid:VE0c/Qjb0IzvfXI7VcEea+480MY	false	protein a tag:?-?	renilla luciferase protein tag:?-?	-	-	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"
uniprotkb:Q7DB77	uniprotkb:P49407	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581.2	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2014)	pubmed:25519916|imex:IM-23549	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-10039808|imex:IM-23549-46	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_004032.2|refseq:NP_064647.1|dip:DIP-29979N|ensembl:ENSG00000137486.17(gene)|ensembl:ENST00000420843.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002031""(G protein-coupled receptor internalization)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0015031""(protein transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031143""(pseudopodium)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031701""(angiotensin receptor binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:1990763""(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|rcsb pdb:7R0C|rcsb pdb:7R0J|rcsb pdb:7SRS|rcsb pdb:8AS2|rcsb pdb:8AS3|rcsb pdb:8AS4|rcsb pdb:8JRV|rcsb pdb:8WRZ|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9839389|panther:PTHR11792(orthology-group)|ensembl:ENST00000360025.7|ensembl:ENSP00000353124.3|ensembl:ENSP00000409581.2"	-	-	-	figure legend:Fig. 5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2014/12/10	2025/03/24	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606	intact-crc:9C419FF431A37C23|rigid:egVpT0wXvb3+UoIaPOCReuZ+1zM	false	protein a tag:?-?	renilla luciferase protein tag:?-?	-	-	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"	"psi-mi:""MI:1220""(tag visualisation by luciferase assay)"
uniprotkb:E1WAC8	uniprotkb:Q9UPT5	intact:EBI-6470515|uniprotkb:Q56020|uniprotkb:Q56025|uniprotkb:Q7CPX1	intact:EBI-720048|uniprotkb:Q96FF0|uniprotkb:Q9H8C3|uniprotkb:Q9H9X3|uniprotkb:Q9HA32|uniprotkb:Q8ND93|uniprotkb:Q8WV91|uniprotkb:B5MC69|uniprotkb:B8XXP2|ensembl:ENSP00000334100.6	psi-mi:sctb1_salts(display_long)|uniprotkb:SL1344_2863(locus name)|uniprotkb:Cell invasion protein SipC(gene name synonym)|uniprotkb:Effector protein SipC(gene name synonym)|uniprotkb:sipC(gene name synonym)|uniprotkb:sctB1(gene name)|psi-mi:sctB1(display_short)|uniprotkb:sspC(gene name synonym)	psi-mi:exoc7_human(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Nichols et al. (2010)	imex:IM-24063|pubmed:20579884	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10759236|imex:IM-24063-3	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005427(Salmonella/Shigella invasin protein C)|refseq:WP_000909019.1|go:""GO:0005576""(extracellular region)|go:""GO:0007015""(actin filament organization)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033644""(host cell membrane)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0042802""(identical protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:1903829""(positive regulation of protein localization)|go:""GO:2000535""(regulation of entry of bacterium into host cell)"	"refseq:NP_001013861.1|refseq:NP_001138769.1|refseq:NP_001138770.1|refseq:NP_001138771.1|refseq:NP_056034.2|refseq:NP_001269242.1|ensembl:ENSG00000182473.22(gene)|ensembl:ENST00000335146.11(transcript)|go:""GO:0000145""(exocyst)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030496""(midbody)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032584""(growth cone membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0090148""(membrane fission)|go:""GO:0090522""(vesicle tethering involved in exocytosis)|go:""GO:0090543""(Flemming body)|go:""GO:1903438""(positive regulation of mitotic cytokinetic process)|go:""GO:2000535""(regulation of entry of bacterium into host cell)|interpro:IPR004140(Exo70 exocyst complex subunit)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR046364|mint:Q9UPT5|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|dip:DIP-37604N|panther:PTHR12542(orthology-group)"	-	-	-	figure legend:1C|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/27	2025/02/27	rogid:bOLPZimRIClEkkIJ5gfG4v091/c216597	rogid:f/uwscxIcAuG96QZzNMQtrzTmeU9606	intact-crc:39E7A2FCC2EC1451|rigid:a9RPHrXVEW7lSA7xhyPZpyci9ow	false	sufficient binding region:200-409|his tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:E1WAC8	uniprotkb:Q96KP1	intact:EBI-6470515|uniprotkb:Q56020|uniprotkb:Q56025|uniprotkb:Q7CPX1	intact:EBI-465715|uniprotkb:Q5JPC8|uniprotkb:Q96AN6|uniprotkb:Q9NUZ8|uniprotkb:Q9UJM7|uniprotkb:B2RBE6|ensembl:ENSP00000230449.4|intact:EBI-21354165	psi-mi:sctb1_salts(display_long)|uniprotkb:SL1344_2863(locus name)|uniprotkb:Cell invasion protein SipC(gene name synonym)|uniprotkb:Effector protein SipC(gene name synonym)|uniprotkb:sipC(gene name synonym)|uniprotkb:sctB1(gene name)|psi-mi:sctB1(display_short)|uniprotkb:sspC(gene name synonym)	psi-mi:exoc2_human(display_long)|uniprotkb:EXOC2(gene name)|psi-mi:EXOC2(display_short)|uniprotkb:SEC5(gene name synonym)|uniprotkb:SEC5L1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Nichols et al. (2010)	imex:IM-24063|pubmed:20579884	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10759246|imex:IM-24063-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005427(Salmonella/Shigella invasin protein C)|refseq:WP_000909019.1|go:""GO:0005576""(extracellular region)|go:""GO:0007015""(actin filament organization)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033644""(host cell membrane)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0042802""(identical protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:1903829""(positive regulation of protein localization)|go:""GO:2000535""(regulation of entry of bacterium into host cell)"	"refseq:XP_016866507.1|refseq:XP_016866508.1|refseq:XP_016866509.1|refseq:XP_016866510.1|refseq:XP_016866511.1|refseq:XP_016866512.1|refseq:XP_016866513.1|refseq:NP_060773.3|ensembl:ENSG00000112685.14(gene)|ensembl:ENST00000230449.9(transcript)|go:""GO:0000145""(exocyst)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0090148""(membrane fission)|go:""GO:0090522""(vesicle tethering involved in exocytosis)|go:""GO:0090543""(Flemming body)|go:""GO:2000535""(regulation of entry of bacterium into host cell)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR029175|interpro:IPR039481|mint:Q96KP1|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|dip:DIP-31795N|panther:PTHR13043(orthology-group)"	-	-	-	figure legend:1B|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/27	2025/02/28	rogid:bOLPZimRIClEkkIJ5gfG4v091/c216597	rogid:7p+4vZ18z6u2PJY0GzbHY+ro0v89606	intact-crc:78BE1477143CD30D|rigid:kQvy3mhSlderZC3CjsOD8ZBhmAY	false	sufficient binding region:200-409|his tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:E1WAC8	uniprotkb:Q96A65	intact:EBI-6470515|uniprotkb:Q56020|uniprotkb:Q56025|uniprotkb:Q7CPX1	intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861.4	psi-mi:sctb1_salts(display_long)|uniprotkb:SL1344_2863(locus name)|uniprotkb:Cell invasion protein SipC(gene name synonym)|uniprotkb:Effector protein SipC(gene name synonym)|uniprotkb:sipC(gene name synonym)|uniprotkb:sctB1(gene name)|psi-mi:sctB1(display_short)|uniprotkb:sspC(gene name synonym)	psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Nichols et al. (2010)	imex:IM-24063|pubmed:20579884	"taxid:216597(salts)|taxid:216597(""Salmonella typhimurium (strain SL1344)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10759246|imex:IM-24063-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005427(Salmonella/Shigella invasin protein C)|refseq:WP_000909019.1|go:""GO:0005576""(extracellular region)|go:""GO:0007015""(actin filament organization)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033644""(host cell membrane)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0042802""(identical protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:1903829""(positive regulation of protein localization)|go:""GO:2000535""(regulation of entry of bacterium into host cell)"	"refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558.16(gene)|ensembl:ENST00000253861.5(transcript)|go:""GO:0000145""(exocyst)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0032584""(growth cone membrane)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0045202""(synapse)|go:""GO:0048341""(paraxial mesoderm formation)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0090148""(membrane fission)|go:""GO:0090522""(vesicle tethering involved in exocytosis)|go:""GO:0090543""(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|interpro:IPR048630|mint:Q96A65|rcsb pdb:7PC5|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|panther:PTHR14146(orthology-group)"	-	-	-	figure legend:1B|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/27	2025/02/28	rogid:bOLPZimRIClEkkIJ5gfG4v091/c216597	rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606	intact-crc:78BE1477143CD30D|rigid:kQvy3mhSlderZC3CjsOD8ZBhmAY	false	sufficient binding region:200-409|his tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P61077	uniprotkb:P0CE12	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-10761075|uniprotkb:Q7CQ69|uniprotkb:Q9RPH0	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	psi-mi:ssph2_salty(display_long)|uniprotkb:Salmonella secreted protein H2(gene name synonym)|uniprotkb:Secreted effector protein sspH2(gene name synonym)|uniprotkb:STM2241(locus name)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SspH2(gene name synonym)	"psi-mi:""MI:0077""(nuclear magnetic resonance)"	Levin et al. (2010)	pubmed:20133640|imex:IM-16252	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-10761070|imex:IM-16252-6|dip:DIP-187344E	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	"refseq:NP_461184.1|refseq:WP_001115840.1|dip:DIP-59215N|go:""GO:0003824""(catalytic activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034052""(positive regulation of plant-type hypersensitive response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070430""(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|interpro:IPR051071|rcsb pdb:3G06|panther:PTHR47114(orthology-group)"	"psi-mi:""MI:0465""(dip)"	-	-	"figure legend:2 and 3A|comment:""\""SspH2 preferentially binds the substrate (i.e., UbcH5 ∼ Ub) as opposed to the product (i.e., free UbcH5) of the Ub-transfer reaction.\""""|comment:The UbcH5 molecule has an active site  C85S mutation, and through this site is linked to Ubiquitin via an ester link, rather than through  a thio-ester link.  This UbcH5-O-Ub conjugate is stable.|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/31	2024/11/14	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA99287	intact-crc:76CC53A8C2297DF2|rigid:+CWhV1iJyRyhg9Ek3243WSpejUs	false	O-glycosyl-L-serine:85-85|mutation:85-85|mutation decreasing interaction:96-96|15n label:?-?	sufficient binding region:477-788	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P61077	uniprotkb:P0CE12	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-10761075|uniprotkb:Q7CQ69|uniprotkb:Q9RPH0	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	psi-mi:ssph2_salty(display_long)|uniprotkb:Salmonella secreted protein H2(gene name synonym)|uniprotkb:Secreted effector protein sspH2(gene name synonym)|uniprotkb:STM2241(locus name)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SspH2(gene name synonym)	"psi-mi:""MI:0997""(ubiquitinase assay)"	Levin et al. (2010)	pubmed:20133640|imex:IM-16252	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0220""(ubiquitination reaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-11364684|imex:IM-16252-7	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	"refseq:NP_461184.1|refseq:WP_001115840.1|dip:DIP-59215N|go:""GO:0003824""(catalytic activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034052""(positive regulation of plant-type hypersensitive response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070430""(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|interpro:IPR051071|rcsb pdb:3G06|panther:PTHR47114(orthology-group)"	-	-	-	figure legend:S1 and S2|comment:In Fig S2 a His-tag is stated to be present on Ssph2 OR E1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/31	2024/11/14	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA99287	intact-crc:EB9686644E6FDAE3|rigid:+CWhV1iJyRyhg9Ek3243WSpejUs	false	-	his tag:?-?|sufficient binding region:477-788	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P61077	uniprotkb:P0CE12	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-10761075|uniprotkb:Q7CQ69|uniprotkb:Q9RPH0	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	psi-mi:ssph2_salty(display_long)|uniprotkb:Salmonella secreted protein H2(gene name synonym)|uniprotkb:Secreted effector protein sspH2(gene name synonym)|uniprotkb:STM2241(locus name)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SspH2(gene name synonym)	"psi-mi:""MI:0997""(ubiquitinase assay)"	Levin et al. (2010)	pubmed:20133640|imex:IM-16252	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0220""(ubiquitination reaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-11364713|imex:IM-16252-8	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	"refseq:NP_461184.1|refseq:WP_001115840.1|dip:DIP-59215N|go:""GO:0003824""(catalytic activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034052""(positive regulation of plant-type hypersensitive response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070430""(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|interpro:IPR051071|rcsb pdb:3G06|panther:PTHR47114(orthology-group)"	-	-	-	figure legend:5|comment:The UbcH5 molecule has an active site  C85S mutation, and through this site is linked to Ubiquitin via an ester link, rather than through  a thio-ester link.  This UbcH5-O-Ub conjugate is stable.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/31	2024/11/14	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA99287	intact-crc:05DEAE1F422DF61A|rigid:+CWhV1iJyRyhg9Ek3243WSpejUs	false	mutation:85-85|O-glycosyl-L-serine:85-85	sufficient binding region:477-788	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P61077	uniprotkb:P0CE12	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-10761075|uniprotkb:Q7CQ69|uniprotkb:Q9RPH0	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	psi-mi:ssph2_salty(display_long)|uniprotkb:Salmonella secreted protein H2(gene name synonym)|uniprotkb:Secreted effector protein sspH2(gene name synonym)|uniprotkb:STM2241(locus name)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SspH2(gene name synonym)	"psi-mi:""MI:0997""(ubiquitinase assay)"	Levin et al. (2010)	pubmed:20133640|imex:IM-16252	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0220""(ubiquitination reaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-11472197|imex:IM-16252-9	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	"refseq:NP_461184.1|refseq:WP_001115840.1|dip:DIP-59215N|go:""GO:0003824""(catalytic activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034052""(positive regulation of plant-type hypersensitive response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070430""(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|interpro:IPR051071|rcsb pdb:3G06|panther:PTHR47114(orthology-group)"	-	-	-	figure legend:1B, 4, S6 and 3B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/31	2024/11/14	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA99287	intact-crc:4E4AF42B05CE0DB7|rigid:+CWhV1iJyRyhg9Ek3243WSpejUs	false	mutation decreasing interaction rate:96-96|mutation decreasing interaction rate:62-62	sufficient binding region:477-788	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P61077	uniprotkb:D0ZVG2	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-11499154|uniprotkb:Q9XDN9	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	psi-mi:ssph1_salt1(display_long)|uniprotkb:sspH1(gene name)|psi-mi:sspH1(display_short)|uniprotkb:Salmonella secreted protein H1(gene name synonym)|uniprotkb:Secreted effector protein SspH1(gene name synonym)|uniprotkb:STM14_1483(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SspH1(gene name synonym)	"psi-mi:""MI:0997""(ubiquitinase assay)"	Levin et al. (2010)	pubmed:20133640|imex:IM-16252	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	"psi-mi:""MI:0220""(ubiquitination reaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-11499174|imex:IM-16252-12	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	"refseq:WP_000481981.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0042025""(host cell nucleus)|rcsb pdb:4NKG|rcsb pdb:4NKH|mint:D0ZVG2|interpro:IPR051071"	-	-	-	figure legend:S2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/31	2024/11/14	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:p5NKW0AINrcuRRQoJotoJqdKoA8588858	intact-crc:83AD19796DDFEC7D|rigid:652ET/ItIeJaCAtDt5y5f8oQfzs	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P61077	uniprotkb:P0CE12	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-10761075|uniprotkb:Q7CQ69|uniprotkb:Q9RPH0	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	psi-mi:ssph2_salty(display_long)|uniprotkb:Salmonella secreted protein H2(gene name synonym)|uniprotkb:Secreted effector protein sspH2(gene name synonym)|uniprotkb:STM2241(locus name)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SspH2(gene name synonym)	"psi-mi:""MI:0997""(ubiquitinase assay)"	Levin et al. (2010)	pubmed:20133640|imex:IM-16252	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0220""(ubiquitination reaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-11499196|imex:IM-16252-13	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	"refseq:NP_461184.1|refseq:WP_001115840.1|dip:DIP-59215N|go:""GO:0003824""(catalytic activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034052""(positive regulation of plant-type hypersensitive response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070430""(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|interpro:IPR051071|rcsb pdb:3G06|panther:PTHR47114(orthology-group)"	-	-	-	figure legend:S2,6|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/31	2024/11/14	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA99287	intact-crc:9A8E53F3F15053F4|rigid:+CWhV1iJyRyhg9Ek3243WSpejUs	false	-	sufficient binding region:477-788|mutation decreasing interaction rate:580-580	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P61077	uniprotkb:P0CE12	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-10761075|uniprotkb:Q7CQ69|uniprotkb:Q9RPH0	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	psi-mi:ssph2_salty(display_long)|uniprotkb:Salmonella secreted protein H2(gene name synonym)|uniprotkb:Secreted effector protein sspH2(gene name synonym)|uniprotkb:STM2241(locus name)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SspH2(gene name synonym)	"psi-mi:""MI:0997""(ubiquitinase assay)"	Levin et al. (2010)	pubmed:20133640|imex:IM-16252	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0220""(ubiquitination reaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-11472233|imex:IM-16252-10	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	"refseq:NP_461184.1|refseq:WP_001115840.1|dip:DIP-59215N|go:""GO:0003824""(catalytic activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034052""(positive regulation of plant-type hypersensitive response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070430""(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|interpro:IPR051071|rcsb pdb:3G06|panther:PTHR47114(orthology-group)"	-	-	-	figure legend:S3A|comment:The use of K48R-Ub   generates high MW ubiquitylation products|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/31	2024/11/14	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA99287	intact-crc:55151C9E3150925E|rigid:+CWhV1iJyRyhg9Ek3243WSpejUs	false	-	sufficient binding region:477-788	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:P61077	uniprotkb:P0CE12	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	intact:EBI-10761075|uniprotkb:Q7CQ69|uniprotkb:Q9RPH0	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	psi-mi:ssph2_salty(display_long)|uniprotkb:Salmonella secreted protein H2(gene name synonym)|uniprotkb:Secreted effector protein sspH2(gene name synonym)|uniprotkb:STM2241(locus name)|uniprotkb:sspH2(gene name)|psi-mi:sspH2(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SspH2(gene name synonym)	"psi-mi:""MI:0997""(ubiquitinase assay)"	Levin et al. (2010)	pubmed:20133640|imex:IM-16252	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0220""(ubiquitination reaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-11472283|imex:IM-16252-11	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	"refseq:NP_461184.1|refseq:WP_001115840.1|dip:DIP-59215N|go:""GO:0003824""(catalytic activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034052""(positive regulation of plant-type hypersensitive response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070430""(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR029487|interpro:IPR032675|interpro:IPR051071|rcsb pdb:3G06|panther:PTHR47114(orthology-group)"	-	-	-	figure legend:S3B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/03/31	2024/11/14	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:U6VccW6U2B+pmhpF0mbOXOcehqA99287	intact-crc:D45252A1E6590C6E|rigid:+CWhV1iJyRyhg9Ek3243WSpejUs	false	-	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:P10599	uniprotkb:D0ZRB2	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|ensembl:ENSP00000363641.5|uniprotkb:Q9UDG5|intact:EBI-1042712	intact:EBI-10762386	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Bernal-Bayard et al. (2009)	pubmed:19690162|imex:IM-26113	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10762382|imex:IM-26113-1	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136810.13(gene)|ensembl:ENST00000374517.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003723""(RNA binding)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0009314""(response to radiation)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0046826""(negative regulation of protein export from nucleus)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071731""(response to nitric oxide)|go:""GO:2000170""(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9818027|refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|panther:PTHR10438(orthology-group)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	-	-	-	figure legend:no figure|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/04/02	2025/02/28	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	intact-crc:047839EBB413E839|rigid:K4CXPM49EBDevqFJKekxFKOvvfY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10599	uniprotkb:D0ZRB2	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|ensembl:ENSP00000363641.5|uniprotkb:Q9UDG5|intact:EBI-1042712	intact:EBI-10762386	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Bernal-Bayard et al. (2009)	pubmed:19690162|imex:IM-26113	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10762409|imex:IM-26113-3	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136810.13(gene)|ensembl:ENST00000374517.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003723""(RNA binding)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0009314""(response to radiation)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0046826""(negative regulation of protein export from nucleus)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071731""(response to nitric oxide)|go:""GO:2000170""(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9818027|refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|panther:PTHR10438(orthology-group)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	-	-	-	figure legend:1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/04/02	2025/02/28	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	intact-crc:282E406E4CC4C062|rigid:K4CXPM49EBDevqFJKekxFKOvvfY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:D0ZRB2	uniprotkb:P10599	intact:EBI-10762386	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|ensembl:ENSP00000363641.5|uniprotkb:Q9UDG5|intact:EBI-1042712	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Bernal-Bayard et al. (2009)	pubmed:19690162|imex:IM-26113	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10817724|imex:IM-26113-11	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"ensembl:ENSG00000136810.13(gene)|ensembl:ENST00000374517.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003723""(RNA binding)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0009314""(response to radiation)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0046826""(negative regulation of protein export from nucleus)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071731""(response to nitric oxide)|go:""GO:2000170""(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9818027|refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|panther:PTHR10438(orthology-group)"	-	-	-	figure legend:1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/04/02	2025/02/28	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	intact-crc:5204E72BDA986DEF|rigid:K4CXPM49EBDevqFJKekxFKOvvfY	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P10599	uniprotkb:D0ZRB2	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|ensembl:ENSP00000363641.5|uniprotkb:Q9UDG5|intact:EBI-1042712	intact:EBI-10762386	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Bernal-Bayard et al. (2009)	pubmed:19690162|imex:IM-26113	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10762422|imex:IM-26113-5	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136810.13(gene)|ensembl:ENST00000374517.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003723""(RNA binding)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0009314""(response to radiation)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0046826""(negative regulation of protein export from nucleus)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071731""(response to nitric oxide)|go:""GO:2000170""(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9818027|refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|panther:PTHR10438(orthology-group)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	-	-	-	figure legend:2A|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	-	2015/04/02	2025/02/28	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	intact-crc:5C2B242DEC1D6888|rigid:K4CXPM49EBDevqFJKekxFKOvvfY	false	glutathione s tranferase tag:n-n	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P10599	uniprotkb:D0ZRB2	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|ensembl:ENSP00000363641.5|uniprotkb:Q9UDG5|intact:EBI-1042712	intact:EBI-10762386	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Bernal-Bayard et al. (2009)	pubmed:19690162|imex:IM-26113	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10817746|imex:IM-26113-13	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136810.13(gene)|ensembl:ENST00000374517.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003723""(RNA binding)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0009314""(response to radiation)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0046826""(negative regulation of protein export from nucleus)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071731""(response to nitric oxide)|go:""GO:2000170""(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9818027|refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|panther:PTHR10438(orthology-group)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	-	-	-	figure legend:3 A/B|comment:treatment of GST-Trx bound to glutathione-agarose beads with H2O2 before the in vitro interaction assay reduced the Slrp-Trx interaction.|antagonist:Hydrogen Peroxide|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/02	2025/02/28	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	intact-crc:ED0843C125434DBC|rigid:K4CXPM49EBDevqFJKekxFKOvvfY	false	glutathione s tranferase tag:n-n	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P10599	uniprotkb:D0ZRB2	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|ensembl:ENSP00000363641.5|uniprotkb:Q9UDG5|intact:EBI-1042712	intact:EBI-10762386	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Bernal-Bayard et al. (2009)	pubmed:19690162|imex:IM-26113	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10762452|imex:IM-26113-7	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136810.13(gene)|ensembl:ENST00000374517.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003723""(RNA binding)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0009314""(response to radiation)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0046826""(negative regulation of protein export from nucleus)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071731""(response to nitric oxide)|go:""GO:2000170""(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9818027|refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|panther:PTHR10438(orthology-group)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	-	-	-	figure legend:2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2015/04/02	2025/02/28	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	intact-crc:30ABD097287A8372|rigid:K4CXPM49EBDevqFJKekxFKOvvfY	false	ha tag:?-?	flag tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:D0ZRB2	uniprotkb:P10599	intact:EBI-10762386	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|ensembl:ENSP00000363641.5|uniprotkb:Q9UDG5|intact:EBI-1042712	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Bernal-Bayard et al. (2009)	pubmed:19690162|imex:IM-26113	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0414""(enzymatic reaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10762467|imex:IM-26113-9	intact-miscore:0.63	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"ensembl:ENSG00000136810.13(gene)|ensembl:ENST00000374517.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003723""(RNA binding)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0009314""(response to radiation)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0046826""(negative regulation of protein export from nucleus)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071731""(response to nitric oxide)|go:""GO:2000170""(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9818027|refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|panther:PTHR10438(orthology-group)"	"go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0016874""(ligase activity)"	-	-	figure legend:4C|resulting-ptm:Trx is ubiquitinated in the presence of SlrP|comment:An E1 molecule was also present, but cannot be identified.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/02	2025/02/28	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	intact-crc:CEA9BC5738872F64|rigid:QSwfIgtEDxMttm1vZsIJcotroL0	false	glutathione s tranferase tag:?-?	glutathione s tranferase tag:n-n|ubiquitinylated lysine:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:D0ZRB2	uniprotkb:P62837	intact:EBI-10762386	intact:EBI-347677|ensembl:ENSP00000381717.3|ensembl:ENSP00000381718.4|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6	psi-mi:slrp_salt1(display_long)|uniprotkb:Secreted effector protein SlrP(gene name synonym)|uniprotkb:STM14_928(locus name)|uniprotkb:slrP(gene name)|psi-mi:slrP(display_short)|uniprotkb:RING-type E3 ubiquitin transferase SlrP(gene name synonym)	"psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 2""(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D2""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)"	"psi-mi:""MI:0415""(enzymatic study)"	Bernal-Bayard et al. (2009)	pubmed:19690162|imex:IM-26113	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0414""(enzymatic reaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10762467|imex:IM-26113-9	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0684""(ancillary)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051071|refseq:WP_000481997.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR029487|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061630""(ubiquitin protein ligase activity)|rcsb pdb:4PUF|mint:D0ZRB2"	"ensembl:ENSG00000131508.17(gene)|ensembl:ENST00000398733.8(transcript)|ensembl:ENST00000398734.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036211""(protein modification process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|rcsb pdb:7R71|rcsb pdb:8B3I|rcsb pdb:8GBQ|rcsb pdb:8GCB|rcsb pdb:8GRM|rcsb pdb:8JWJ|rcsb pdb:8JWU|rcsb pdb:8VK8|rcsb pdb:8VK9|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|panther:PTHR24068(orthology-group)"	"go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0016874""(ligase activity)"	-	-	figure legend:4C|resulting-ptm:Trx is ubiquitinated in the presence of SlrP|comment:An E1 molecule was also present, but cannot be identified.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/02	2025/02/28	rogid:IGfbzFpRlBfAS40k6F+U2+D9ezo588858	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:CEA9BC5738872F64|rigid:QSwfIgtEDxMttm1vZsIJcotroL0	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q8IWE5	uniprotkb:Q56061	intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956.3|intact:EBI-11039943|uniprotkb:Q5VVD7	intact:EBI-10765408	psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short)	psi-mi:sifa_salty(display_long)|uniprotkb:STM1224(locus name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	"psi-mi:""MI:0096""(pull down)"	Jackson et al. (2008)	pubmed:18787122|imex:IM-9657	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-10765402|imex:IM-9657-3|dip:DIP-88403E	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:54260""|dip:DIP-46410N|ensembl:ENSG00000116786.14(gene)|ensembl:ENST00000375799.8(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0007030""(Golgi organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0032418""(lysosome localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|interpro:IPR047327|interpro:IPR053015|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|rcsb pdb:8JCA|refseq:NP_055979.2|refseq:XP_005245847.1|panther:PTHR46556(orthology-group)"	"refseq:NP_460194.1|refseq:WP_001520468.1|dip:DIP-46411N|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0044082""(symbiont-mediated perturbation of host small GTPase-mediated signal transduction)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|interpro:IPR010637(Sif)|interpro:IPR044928|rcsb pdb:3CXB|rcsb pdb:3HW2"	"psi-mi:""MI:0465""(dip)"	-	crc64:83C6185148A774B9	figure legend:1A, 2D, 3A-D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.0x10^-7(molar)	2015/04/02	2024/11/14	rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk99287	intact-crc:F0C68E3833BCF1BE|rigid:Lz4XVeGH3GXbQCi5yjJxJeu9KVw	false	binding-associated region:762-885	glutathione s tranferase tag:?-?|mutation decreasing interaction:201-201,197-197	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:P51151	uniprotkb:Q56061	intact:EBI-4401353|uniprotkb:Q6ICN1|uniprotkb:A8K390|ensembl:ENSP00000420127.1|ensembl:ENSP00000480777.1	intact:EBI-10765408	psi-mi:rab9a_human(display_long)|uniprotkb:RAB9A(gene name)|psi-mi:RAB9A(display_short)|uniprotkb:RAB9(gene name synonym)	psi-mi:sifa_salty(display_long)|uniprotkb:STM1224(locus name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	"psi-mi:""MI:0096""(pull down)"	Jackson et al. (2008)	pubmed:18787122|imex:IM-9657	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-10765455|imex:IM-9657-5	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_016885453.1|refseq:NP_001182257.1|refseq:NP_004242.1|dip:DIP-46409N|ensembl:ENSG00000123595.8(gene)|ensembl:ENST00000464506.2(transcript)|ensembl:ENST00000618931.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|go:""GO:0019003""(GDP binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0032482""(Rab protein signal transduction)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042470""(melanosome)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0052403""(obsolete negative regulation by host of symbiont catalytic activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041824|mint:P51151|rcsb pdb:1WMS|rcsb pdb:7E1T|reactome:R-HSA-6811440|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9706019|panther:PTHR47981(orthology-group)"	"refseq:NP_460194.1|refseq:WP_001520468.1|dip:DIP-46411N|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0044082""(symbiont-mediated perturbation of host small GTPase-mediated signal transduction)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|interpro:IPR010637(Sif)|interpro:IPR044928|rcsb pdb:3CXB|rcsb pdb:3HW2"	-	-	crc64:83C6185148A774B9	figure legend:2B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/02	2025/03/05	rogid:x0BjgzGEj7mPNlt2CQLkHtqQzDQ9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk99287	intact-crc:ACBE2631055BE7A4|rigid:w7LJbCffEE8JeAg32m5M6f33pjI	false	glutathione s tranferase tag:?-?|mutation:66-66	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q8IWE5	uniprotkb:Q56061	intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956.3|intact:EBI-11039943|uniprotkb:Q5VVD7	intact:EBI-10765408	psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short)	psi-mi:sifa_salty(display_long)|uniprotkb:STM1224(locus name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	"psi-mi:""MI:0096""(pull down)"	Jackson et al. (2008)	pubmed:18787122|imex:IM-9657	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-10765471|imex:IM-9657-6	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0941""(competitor)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:54260""|dip:DIP-46410N|ensembl:ENSG00000116786.14(gene)|ensembl:ENST00000375799.8(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0007030""(Golgi organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0032418""(lysosome localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|interpro:IPR047327|interpro:IPR053015|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|rcsb pdb:8JCA|refseq:NP_055979.2|refseq:XP_005245847.1|panther:PTHR46556(orthology-group)"	"refseq:NP_460194.1|refseq:WP_001520468.1|dip:DIP-46411N|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0044082""(symbiont-mediated perturbation of host small GTPase-mediated signal transduction)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|interpro:IPR010637(Sif)|interpro:IPR044928|rcsb pdb:3CXB|rcsb pdb:3HW2"	-	-	crc64:83C6185148A774B9	figure legend:2C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/02	2025/03/05	rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk99287	intact-crc:74B735CAB2A3201C|rigid:w7LJbCffEE8JeAg32m5M6f33pjI	false	glutathione s tranferase tag:?-?|binding-associated region:762-885	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:A0A0F6B063	uniprotkb:Q8IWE5	intact:EBI-11477981	intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956.3|intact:EBI-11039943|uniprotkb:Q5VVD7	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Ohlson et al. (2008)	pubmed:18996344|imex:IM-26105	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-11478006|imex:IM-26105-5	intact-miscore:0.58	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	"efo:""Orphanet:54260""|dip:DIP-46410N|ensembl:ENSG00000116786.14(gene)|ensembl:ENST00000375799.8(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0007030""(Golgi organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0032418""(lysosome localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|interpro:IPR047327|interpro:IPR053015|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|rcsb pdb:8JCA|refseq:NP_055979.2|refseq:XP_005245847.1|panther:PTHR46556(orthology-group)"	"go:""GO:1903527""(positive regulation of membrane tubulation)|go:""GO:0010008""(endosome membrane)"	-	-	figure legend:2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2015/04/07	2024/11/14	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606	intact-crc:DCEDB46130ED269A|rigid:s9QdNpuEJDdAe6iYgaz0BU7G91g	false	green fluorescent protein tag:n-n	myc tag:n-n	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q8IWE5	uniprotkb:A0A0F6B063	intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956.3|intact:EBI-11039943|uniprotkb:Q5VVD7	intact:EBI-11477981	psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short)	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Ohlson et al. (2008)	pubmed:18996344|imex:IM-26105	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-11478186|imex:IM-26105-11	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:54260""|dip:DIP-46410N|ensembl:ENSG00000116786.14(gene)|ensembl:ENST00000375799.8(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0007030""(Golgi organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0032418""(lysosome localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|interpro:IPR047327|interpro:IPR053015|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|rcsb pdb:8JCA|refseq:NP_055979.2|refseq:XP_005245847.1|panther:PTHR46556(orthology-group)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	-	comment:Skip mutation corresponding to UniProt id Q8IWE5 seq are different from what is stated in the publication	-	figure legend:5A and E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/07	2024/11/14	rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	intact-crc:E99B7B487286DBC4|rigid:HyF/L1jvgJpGGS1ZPtwWoob+CD8	false	sufficient binding region:774-883(IPR001849)|mutation decreasing interaction:831-831|mutation decreasing interaction:869-869|mutation decreasing interaction:828-828|mutation decreasing interaction:831-831	his tag:?-?|mutation decreasing interaction:130-130|mutation decreasing interaction:131-131|sufficient binding region:1-330	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q8IWE5	uniprotkb:A0A0F6B063	intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956.3|intact:EBI-11039943|uniprotkb:Q5VVD7	intact:EBI-11477981	psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short)	psi-mi:a0a0f6b063_salt1(display_long)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)|uniprotkb:STM14_1400(locus name)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Ohlson et al. (2008)	pubmed:18996344|imex:IM-26105	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:588858(salt1)|taxid:588858(""Salmonella typhimurium (strain 14028s / SGSC 2262)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-11478161|imex:IM-26105-7	intact-miscore:0.58	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:54260""|dip:DIP-46410N|ensembl:ENSG00000116786.14(gene)|ensembl:ENST00000375799.8(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0007030""(Golgi organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0032418""(lysosome localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|interpro:IPR047327|interpro:IPR053015|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|rcsb pdb:8JCA|refseq:NP_055979.2|refseq:XP_005245847.1|panther:PTHR46556(orthology-group)"	"interpro:IPR010637(Sif)|refseq:WP_001520468.1|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044928|mint:A0A0F6B063"	-	-	-	figure legend:5B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.58x10^-6(molar)	2015/04/07	2024/11/14	rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk588858	intact-crc:510F4DC33F78C603|rigid:HyF/L1jvgJpGGS1ZPtwWoob+CD8	false	sufficient binding region:774-883	sufficient binding region:1-330	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8IWE5	uniprotkb:Q56061	intact:EBI-726484|uniprotkb:O94928|uniprotkb:Q5VT65|uniprotkb:Q7L8G1|uniprotkb:Q8IVT7|uniprotkb:Q8N2T4|uniprotkb:Q96AY0|uniprotkb:Q9NTF7|uniprotkb:Q6NUH9|intact:EBI-28967282|ensembl:ENSP00000364956.3|intact:EBI-11039943|uniprotkb:Q5VVD7	intact:EBI-10765408	psi-mi:pkhm2_human(display_long)|uniprotkb:KIAA0842(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Salmonella-induced filaments A and kinesin-interacting protein(gene name synonym)|uniprotkb:PLEKHM2(gene name)|psi-mi:PLEKHM2(display_short)	psi-mi:sifa_salty(display_long)|uniprotkb:STM1224(locus name)|uniprotkb:sifA(gene name)|psi-mi:sifA(display_short)	"psi-mi:""MI:0114""(x-ray crystallography)"	Ohlson et al. (2008)	pubmed:18996344|imex:IM-26105	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-11478177|wwpdb:3cxb|imex:IM-26105-9	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:54260""|dip:DIP-46410N|ensembl:ENSG00000116786.14(gene)|ensembl:ENST00000375799.8(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0007030""(Golgi organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0032418""(lysosome localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037213|interpro:IPR047327|interpro:IPR053015|rcsb pdb:3CXB|rcsb pdb:3HW2|rcsb pdb:3ZFW|rcsb pdb:8JCA|refseq:NP_055979.2|refseq:XP_005245847.1|panther:PTHR46556(orthology-group)"	"refseq:NP_460194.1|refseq:WP_001520468.1|dip:DIP-46411N|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0044082""(symbiont-mediated perturbation of host small GTPase-mediated signal transduction)|go:""GO:0141028""(symbiont-mediated perturbation of host microtubule cytoskeleton)|interpro:IPR010637(Sif)|interpro:IPR044928|rcsb pdb:3CXB|rcsb pdb:3HW2"	-	-	crc64:83C6185148A774B9	figure legend:5C, 6A and table S1|3d-resolution:2.6A|3d-r-factors:R working 0.258 R free 0.288|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/07	2024/11/14	rogid:i7gH6BiDpQGSXReuHc81laPbWKo9606	rogid:fkJB9FeNbgsJHGemS/FGxtsMitk99287	intact-crc:1D8D7C92B9607681|rigid:Lz4XVeGH3GXbQCi5yjJxJeu9KVw	false	sufficient binding region:773-884	sufficient binding region:1-336	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O30916	uniprotkb:P60953	intact:EBI-11167349|uniprotkb:Q8ZQ57|uniprotkb:Q9L889	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:sopb_salty(display_long)|uniprotkb:Effector protein SopB(gene name synonym)|uniprotkb:sopB(gene name)|psi-mi:sopB(display_short)|uniprotkb:sigD(gene name synonym)|uniprotkb:STM1091(locus name)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Rodríguez-Escudero et al. (2011)	pubmed:21435037|imex:IM-26084	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10817795|imex:IM-26084-1	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001166946.1|rcsb pdb:4DID|interpro:IPR008108(Type III secretion system outer membrane, B protein)|go:""GO:0020003""(symbiont-containing vacuole)|go:""GO:0023057""(negative regulation of signaling)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0042577""(lipid phosphatase activity)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045859""(regulation of protein kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0140677""(molecular function activator activity)|rcsb pdb:8JZL|refseq:NP_460064.1"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	-	-	-	figure legend:2A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/04/07	2024/11/07	rogid:UQwDH+y4MXGRiHj5Fn4PM/N6afI99287	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:19A99C969FA45B2F|rigid:+Nca9jRoJoc3BrH+eHDlnQSWVeI	false	mutation:466-466|glutathione s tranferase tag:n-n	ha tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:O30916	uniprotkb:P60953	intact:EBI-11167349|uniprotkb:Q8ZQ57|uniprotkb:Q9L889	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:sopb_salty(display_long)|uniprotkb:Effector protein SopB(gene name synonym)|uniprotkb:sopB(gene name)|psi-mi:sopB(display_short)|uniprotkb:sigD(gene name synonym)|uniprotkb:STM1091(locus name)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Rodríguez-Escudero et al. (2011)	pubmed:21435037|imex:IM-26084	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10817812|imex:IM-26084-3	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001166946.1|rcsb pdb:4DID|interpro:IPR008108(Type III secretion system outer membrane, B protein)|go:""GO:0020003""(symbiont-containing vacuole)|go:""GO:0023057""(negative regulation of signaling)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0042577""(lipid phosphatase activity)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045859""(regulation of protein kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0140677""(molecular function activator activity)|rcsb pdb:8JZL|refseq:NP_460064.1"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	-	-	-	figure legend:2B|resulting-ptm:Ubiquitinated SopB was observed when hCdc42 was coexpressed|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/04/07	2024/11/07	rogid:UQwDH+y4MXGRiHj5Fn4PM/N6afI99287	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:0B35D0AA10757F85|rigid:+Nca9jRoJoc3BrH+eHDlnQSWVeI	false	mutation:466-466|glutathione s tranferase tag:n-n	ha tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P60953	uniprotkb:O30916	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	intact:EBI-11167349|uniprotkb:Q8ZQ57|uniprotkb:Q9L889	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:sopb_salty(display_long)|uniprotkb:Effector protein SopB(gene name synonym)|uniprotkb:sopB(gene name)|psi-mi:sopB(display_short)|uniprotkb:sigD(gene name synonym)|uniprotkb:STM1091(locus name)	"psi-mi:""MI:0096""(pull down)"	Rodríguez-Escudero et al. (2011)	pubmed:21435037|imex:IM-26084	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10817918|imex:IM-26084-13	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	"refseq:WP_001166946.1|rcsb pdb:4DID|interpro:IPR008108(Type III secretion system outer membrane, B protein)|go:""GO:0020003""(symbiont-containing vacuole)|go:""GO:0023057""(negative regulation of signaling)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0042577""(lipid phosphatase activity)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045859""(regulation of protein kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0140677""(molecular function activator activity)|rcsb pdb:8JZL|refseq:NP_460064.1"	-	-	comment:in the paper R468A	figure legend:5B|resulting-ptm:Ubiquitinated SopB was observed when hCdc42 was coexpressed|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/04/07	2024/11/07	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rogid:UQwDH+y4MXGRiHj5Fn4PM/N6afI99287	intact-crc:A82A3FED2666825C|rigid:+Nca9jRoJoc3BrH+eHDlnQSWVeI	false	ha tag:n-n	mutation:466-466|green fluorescent protein tag:?-?|mutation decreasing interaction:52-52|mutation decreasing interaction:63-63,466-466|mutation decreasing interaction:73-73,466-466|mutation decreasing interaction:76-76,466-466|mutation decreasing interaction:466-466,84-84|sufficient binding region:1-238	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:O30916	uniprotkb:P60953	intact:EBI-11167349|uniprotkb:Q8ZQ57|uniprotkb:Q9L889	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:sopb_salty(display_long)|uniprotkb:Effector protein SopB(gene name synonym)|uniprotkb:sopB(gene name)|psi-mi:sopB(display_short)|uniprotkb:sigD(gene name synonym)|uniprotkb:STM1091(locus name)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Rodríguez-Escudero et al. (2011)	pubmed:21435037|imex:IM-26084	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10817831|imex:IM-26084-5	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001166946.1|rcsb pdb:4DID|interpro:IPR008108(Type III secretion system outer membrane, B protein)|go:""GO:0020003""(symbiont-containing vacuole)|go:""GO:0023057""(negative regulation of signaling)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0042577""(lipid phosphatase activity)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045859""(regulation of protein kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0140677""(molecular function activator activity)|rcsb pdb:8JZL|refseq:NP_460064.1"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	-	-	-	figure legend:3A|resulting-ptm:Ubiquitinated SopB was observed when hCdc42 was coexpressed|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/04/07	2024/11/07	rogid:UQwDH+y4MXGRiHj5Fn4PM/N6afI99287	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:512B8BC0913138BD|rigid:+Nca9jRoJoc3BrH+eHDlnQSWVeI	false	mutation:466-466|green fluorescent protein tag:?-?	ha tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:O30916	uniprotkb:P60953	intact:EBI-11167349|uniprotkb:Q8ZQ57|uniprotkb:Q9L889	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:sopb_salty(display_long)|uniprotkb:Effector protein SopB(gene name synonym)|uniprotkb:sopB(gene name)|psi-mi:sopB(display_short)|uniprotkb:sigD(gene name synonym)|uniprotkb:STM1091(locus name)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Rodríguez-Escudero et al. (2011)	pubmed:21435037|imex:IM-26084	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10817852|imex:IM-26084-7	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001166946.1|rcsb pdb:4DID|interpro:IPR008108(Type III secretion system outer membrane, B protein)|go:""GO:0020003""(symbiont-containing vacuole)|go:""GO:0023057""(negative regulation of signaling)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0042577""(lipid phosphatase activity)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045859""(regulation of protein kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0140677""(molecular function activator activity)|rcsb pdb:8JZL|refseq:NP_460064.1"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	-	-	-	figure legend:5C|resulting-ptm:Ubiquitinated SopB was observed when hCdc42 was coexpressed|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/04/07	2024/11/07	rogid:UQwDH+y4MXGRiHj5Fn4PM/N6afI99287	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:AFCED0D470C0D0B7|rigid:+Nca9jRoJoc3BrH+eHDlnQSWVeI	false	mutation:466-466|glutathione s tranferase tag:?-?|mutation decreasing interaction:84-84|mutation decreasing interaction:76-76|mutation decreasing interaction:73-73|mutation decreasing interaction:63-63	ha tag:n-n	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P60953	uniprotkb:P74873	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	intact:EBI-1030433|uniprotkb:Q7CPX3	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:sptp_salty(display_long)|uniprotkb:sptP(gene name)|psi-mi:sptP(display_short)|uniprotkb:STM2878(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Rodríguez-Escudero et al. (2011)	pubmed:21435037|imex:IM-26084	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10817872|imex:IM-26084-9	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	"interpro:IPR044899|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR015203(SicP binding)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR003546(Protein-tyrosine phosphatase, modular, Salmonella/Yersinia)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR014773(Yersinia virulence determinant YopE, C-terminal)|rcsb pdb:1G4U|rcsb pdb:1G4W|rcsb pdb:1JYO|interpro:IPR029021|interpro:IPR050348|refseq:WP_000922300.1|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR037168|refseq:NP_461799.1|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005615""(extracellular space)|go:""GO:0030430""(host cell cytoplasm)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)"	-	-	-	figure legend:3A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/04/07	2024/11/07	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rogid:19HXLRiZWVMrCUCAFRkA0o0+7LQ99287	intact-crc:B53792B248EB5CDF|rigid:rXAm2Plr5s/AhHk0MkWvdlFbRmA	false	ha tag:n-n	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P60953	uniprotkb:Q7CQD4	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	intact:EBI-11167441|uniprotkb:Q9KIZ2|uniprotkb:Q9L8K7	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:sope2_salty(display_long)|uniprotkb:Effector protein sopE2(gene name synonym)|uniprotkb:Toxin sopE2(gene name synonym)|uniprotkb:STM1855(locus name)|uniprotkb:sopE2(gene name)|psi-mi:sopE2(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Rodríguez-Escudero et al. (2011)	pubmed:21435037|imex:IM-26084	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:99287(salty)|taxid:99287(Salmonella typhimurium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:1335""(HPIDb)"	intact:EBI-10817897|imex:IM-26084-11	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	"refseq:WP_000182072.1|rcsb pdb:1R6E|rcsb pdb:1R9K|interpro:IPR005414(Salmonella type III secretion SopE effector protein)|interpro:IPR016019(Salmonella type III secretion SopE effector protein, GEF domain)|interpro:IPR016018(Salmonella type III secretion SopE effector protein, N-terminal)|interpro:IPR035949|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0030036""(actin cytoskeleton organization)|refseq:NP_460811.1"	-	-	-	figure legend:3A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/04/07	2024/11/07	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rogid:4zg9vu4xTwQdifNwTgAd4RJd7X499287	intact-crc:FA2FF8C901994C01|rigid:z/YqNvO2Qpqd2Xw+evuH188CTRA	false	ha tag:n-n	glutathione s tranferase tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P71213	uniprotkb:P01009	intact:EBI-2615322	intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068.4|ensembl:ENSP00000376802.4|ensembl:ENSP00000376803.4|ensembl:ENSP00000385960.4|ensembl:ENSP00000390299.1|ensembl:ENSP00000408474.1|ensembl:ENSP00000416066.1|ensembl:ENSP00000416354.3|ensembl:ENSP00000490054.1	psi-mi:p71213_ecolx(display_long)|uniprotkb:ABE91_000945(orf name)|uniprotkb:espB(gene name)|psi-mi:espB(display_short)|uniprotkb:C0P57_004575(orf name)|uniprotkb:CTR35_004779(orf name)|uniprotkb:FIJ20_24815(orf name)|uniprotkb:G4A47_05135(orf name)|uniprotkb:G4A38_02845(orf name)|uniprotkb:B6R15_003131(orf name)|uniprotkb:C9194_00865(orf name)|uniprotkb:NCTC8960_02077(orf name)|uniprotkb:DIV22_19905(orf name)|uniprotkb:J0541_004678(orf name)|uniprotkb:GGB84_001983(orf name)	psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Knappstein et al. (2004)	pubmed:15271889|imex:IM-20447	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2615346|imex:IM-20447-2	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008611(Enterobacterial EspB)|refseq:WP_001092012.1	"efo:""Orphanet:178396""|efo:""Orphanet:586""|efo:""Orphanet:60""|dip:DIP-35493N|ensembl:ENSG00000197249.14(gene)|ensembl:ENST00000355814.8(transcript)|ensembl:ENST00000393087.9(transcript)|ensembl:ENST00000393088.8(transcript)|ensembl:ENST00000404814.8(transcript)|ensembl:ENST00000437397.5(transcript)|ensembl:ENST00000440909.5(transcript)|ensembl:ENST00000448921.5(transcript)|ensembl:ENST00000449399.7(transcript)|ensembl:ENST00000636712.1(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006953""(acute-phase response)|go:""GO:0007596""(blood coagulation)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1D5S|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:8P4J|rcsb pdb:8P4U|rcsb pdb:8PI2|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275|refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|panther:PTHR11461(orthology-group)"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	figure legend:Fig. 1|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/03/12	2025/03/10	rogid:BHFwhK2i0UkoH3BMkj4JHGzABlE562	rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606	intact-crc:B0B47EC3B89CB01D|rigid:/JEOetdR/P4ZOUyoas5AIzEuqRs	false	his tag:c-c	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P01009	uniprotkb:P71213	intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068.4|ensembl:ENSP00000376802.4|ensembl:ENSP00000376803.4|ensembl:ENSP00000385960.4|ensembl:ENSP00000390299.1|ensembl:ENSP00000408474.1|ensembl:ENSP00000416066.1|ensembl:ENSP00000416354.3|ensembl:ENSP00000490054.1	intact:EBI-2615322	psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym)	psi-mi:p71213_ecolx(display_long)|uniprotkb:ABE91_000945(orf name)|uniprotkb:espB(gene name)|psi-mi:espB(display_short)|uniprotkb:C0P57_004575(orf name)|uniprotkb:CTR35_004779(orf name)|uniprotkb:FIJ20_24815(orf name)|uniprotkb:G4A47_05135(orf name)|uniprotkb:G4A38_02845(orf name)|uniprotkb:B6R15_003131(orf name)|uniprotkb:C9194_00865(orf name)|uniprotkb:NCTC8960_02077(orf name)|uniprotkb:DIV22_19905(orf name)|uniprotkb:J0541_004678(orf name)|uniprotkb:GGB84_001983(orf name)	"psi-mi:""MI:0096""(pull down)"	Knappstein et al. (2004)	pubmed:15271889|imex:IM-20447	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2615327|imex:IM-20447-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:178396""|efo:""Orphanet:586""|efo:""Orphanet:60""|dip:DIP-35493N|ensembl:ENSG00000197249.14(gene)|ensembl:ENST00000355814.8(transcript)|ensembl:ENST00000393087.9(transcript)|ensembl:ENST00000393088.8(transcript)|ensembl:ENST00000404814.8(transcript)|ensembl:ENST00000437397.5(transcript)|ensembl:ENST00000440909.5(transcript)|ensembl:ENST00000448921.5(transcript)|ensembl:ENST00000449399.7(transcript)|ensembl:ENST00000636712.1(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006953""(acute-phase response)|go:""GO:0007596""(blood coagulation)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1D5S|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:8P4J|rcsb pdb:8P4U|rcsb pdb:8PI2|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275|refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|panther:PTHR11461(orthology-group)"	interpro:IPR008611(Enterobacterial EspB)|refseq:WP_001092012.1	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	figure legend:Fig. 1|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/03/12	2025/03/10	rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606	rogid:BHFwhK2i0UkoH3BMkj4JHGzABlE562	intact-crc:D243249A05760F22|rigid:/JEOetdR/P4ZOUyoas5AIzEuqRs	false	-	his tag:c-c	-	-	"psi-mi:""MI:0039""(edman degradation)"	"psi-mi:""MI:0039""(edman degradation)"
uniprotkb:P71213	uniprotkb:P01009	intact:EBI-2615322	intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068.4|ensembl:ENSP00000376802.4|ensembl:ENSP00000376803.4|ensembl:ENSP00000385960.4|ensembl:ENSP00000390299.1|ensembl:ENSP00000408474.1|ensembl:ENSP00000416066.1|ensembl:ENSP00000416354.3|ensembl:ENSP00000490054.1	psi-mi:p71213_ecolx(display_long)|uniprotkb:ABE91_000945(orf name)|uniprotkb:espB(gene name)|psi-mi:espB(display_short)|uniprotkb:C0P57_004575(orf name)|uniprotkb:CTR35_004779(orf name)|uniprotkb:FIJ20_24815(orf name)|uniprotkb:G4A47_05135(orf name)|uniprotkb:G4A38_02845(orf name)|uniprotkb:B6R15_003131(orf name)|uniprotkb:C9194_00865(orf name)|uniprotkb:NCTC8960_02077(orf name)|uniprotkb:DIV22_19905(orf name)|uniprotkb:J0541_004678(orf name)|uniprotkb:GGB84_001983(orf name)	psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Knappstein et al. (2004)	pubmed:15271889|imex:IM-20447	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2624217|imex:IM-20447-3	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008611(Enterobacterial EspB)|refseq:WP_001092012.1	"efo:""Orphanet:178396""|efo:""Orphanet:586""|efo:""Orphanet:60""|dip:DIP-35493N|ensembl:ENSG00000197249.14(gene)|ensembl:ENST00000355814.8(transcript)|ensembl:ENST00000393087.9(transcript)|ensembl:ENST00000393088.8(transcript)|ensembl:ENST00000404814.8(transcript)|ensembl:ENST00000437397.5(transcript)|ensembl:ENST00000440909.5(transcript)|ensembl:ENST00000448921.5(transcript)|ensembl:ENST00000449399.7(transcript)|ensembl:ENST00000636712.1(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006953""(acute-phase response)|go:""GO:0007596""(blood coagulation)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1D5S|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:8P4J|rcsb pdb:8P4U|rcsb pdb:8PI2|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275|refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|panther:PTHR11461(orthology-group)"	"go:""GO:0051701""(biological process involved in interaction with host)"	-	-	figure legend:Fig. 1|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/03/12	2025/03/10	rogid:BHFwhK2i0UkoH3BMkj4JHGzABlE562	rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606	intact-crc:0C036A103A124D1D|rigid:/JEOetdR/P4ZOUyoas5AIzEuqRs	false	his tag:c-c	-	-	-	"psi-mi:""MI:0039""(edman degradation)"	"psi-mi:""MI:0039""(edman degradation)"
uniprotkb:P0A6Y8	uniprotkb:P04637	intact:EBI-542092|uniprotkb:P04475	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5|ensembl:ENSP00000269305.4|ensembl:ENSP00000391478.2|ensembl:ENSP00000424104.2|ensembl:ENSP00000426252.2|ensembl:ENSP00000519624.1|ensembl:ENSP00000519626.1	psi-mi:dnak_ecoli(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpF(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:b0014(locus name)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:JW0013(locus name)	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	"psi-mi:""MI:0004""(affinity chromatography technology)"	Iosefson et al. (2010)	pubmed:20153329|imex:IM-15644|mint:MINT-7557550|mint:d-09-02229	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7806506|mint:MINT-7557591|imex:IM-15644-2	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414555.1|refseq:WP_000516135.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016234""(inclusion body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0016989""(sigma factor antagonist activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042026""(protein refolding)|go:""GO:0043335""(protein unfolding)|go:""GO:0043531""(ADP binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990169""(stress response to copper ion)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1BPR|rcsb pdb:1DG4|rcsb pdb:1DKG|rcsb pdb:1DKX|rcsb pdb:1DKY|rcsb pdb:1DKZ|rcsb pdb:1Q5L|rcsb pdb:2BPR|rcsb pdb:2KHO|rcsb pdb:3DPO|rcsb pdb:3DPP|rcsb pdb:3DPQ|rcsb pdb:3QNJ|rcsb pdb:4B9Q|rcsb pdb:4E81|rcsb pdb:4EZN|rcsb pdb:4EZO|rcsb pdb:4EZP|rcsb pdb:4EZQ|rcsb pdb:4EZR|rcsb pdb:4EZS|rcsb pdb:4EZT|rcsb pdb:4EZU|rcsb pdb:4EZV|rcsb pdb:4EZW|rcsb pdb:4EZX|rcsb pdb:4EZY|rcsb pdb:4EZZ|rcsb pdb:4F00|rcsb pdb:4F01|rcsb pdb:4HY9|rcsb pdb:4HYB|rcsb pdb:4JN4|rcsb pdb:4JNE|rcsb pdb:4JNF|rcsb pdb:4JWC|rcsb pdb:4JWD|rcsb pdb:4JWE|rcsb pdb:4JWI|rcsb pdb:4R5G|rcsb pdb:4R5I|rcsb pdb:4R5J|rcsb pdb:4R5K|rcsb pdb:4R5L|rcsb pdb:5NRO|rcsb pdb:5OOW|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7KO2|rcsb pdb:7KRT|rcsb pdb:7KRU|rcsb pdb:7KRV|rcsb pdb:7KRW|rcsb pdb:7KZI|rcsb pdb:7KZU|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|rcsb pdb:7RAX|dip:DIP-35751N|mint:P0A6Y8|panther:PTHR19375(orthology-group)|mint:MINT-7557593(identity)"	"efo:""Orphanet:1333""|efo:""Orphanet:145""|efo:""Orphanet:1501""|efo:""Orphanet:210159""|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:251899""|efo:""Orphanet:2807""|efo:""Orphanet:293199""|efo:""Orphanet:3318""|efo:""Orphanet:524""|efo:""Orphanet:585909""|efo:""Orphanet:668""|efo:""Orphanet:67038""|efo:""Orphanet:70573""|efo:""Orphanet:96253""|efo:""Orphanet:99756""|efo:""Orphanet:99757""|panther:PTHR11447(orthology-group)|efo:""Orphanet:52688""|ensembl:ENSG00000141510.19(gene)|ensembl:ENST00000269305.9(transcript)|ensembl:ENST00000445888.6(transcript)|ensembl:ENST00000503591.2(transcript)|ensembl:ENST00000508793.6(transcript)|ensembl:ENST00000714357.1(transcript)|ensembl:ENST00000714359.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000423""(mitophagy)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001094""(TFIID-class transcription factor complex binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001756""(somitogenesis)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0002020""(protease binding)|go:""GO:0002039""(p53 binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002309""(T cell proliferation involved in immune response)|go:""GO:0002326""(B cell lineage commitment)|go:""GO:0002360""(T cell lineage commitment)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005507""(copper ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005657""(replication fork)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006914""(autophagy)|go:""GO:0006974""(DNA damage response)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0006978""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:0006983""(ER overload response)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007369""(gastrulation)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007406""(negative regulation of neuroblast proliferation)|go:""GO:0008104""(protein localization)|go:""GO:0008156""(negative regulation of DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0009299""(mRNA transcription)|go:""GO:0009303""(rRNA transcription)|go:""GO:0009651""(response to salt stress)|go:""GO:0010165""(response to X-ray)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010659""(cardiac muscle cell apoptotic process)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016032""(viral process)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016605""(PML body)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019661""(glucose catabolic process to lactate via pyruvate)|go:""GO:0019899""(enzyme binding)|go:""GO:0021549""(cerebellum development)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034103""(regulation of tissue remodeling)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035033""(histone deacetylase regulator activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035794""(positive regulation of mitochondrial membrane permeability)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036310""(ATP-dependent DNA/DNA annealing activity)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043073""(germ cell nucleus)|go:""GO:0043153""(entrainment of circadian clock by photoperiod)|go:""GO:0043504""(mitochondrial DNA repair)|go:""GO:0043516""(regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045899""(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048512""(circadian behavior)|go:""GO:0048539""(bone marrow development)|go:""GO:0048568""(embryonic organ development)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051097""(negative regulation of helicase activity)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051276""(chromosome organization)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070242""(thymocyte apoptotic process)|go:""GO:0070245""(positive regulation of thymocyte apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071494""(cellular response to UV-C)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0072331""(signal transduction by p53 class mediator)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0072717""(cellular response to actinomycin D)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090399""(replicative senescence)|go:""GO:0090403""(oxidative stress-induced premature senescence)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097252""(oligodendrocyte apoptotic process)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901525""(negative regulation of mitophagy)|go:""GO:1902108""(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902253""(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:1902749""(regulation of cell cycle G2/M phase transition)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903451""(negative regulation of G1 to G0 transition)|go:""GO:1903799""(negative regulation of miRNA processing)|go:""GO:1904024""(negative regulation of glucose catabolic process to lactate via pyruvate)|go:""GO:1905856""(negative regulation of pentose-phosphate shunt)|go:""GO:1990144""(intrinsic apoptotic signaling pathway in response to hypoxia)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000269""(regulation of fibroblast apoptotic process)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2000647""(negative regulation of stem cell proliferation)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872(""p53 transactivation domain (TAD)"")|interpro:IPR036674|interpro:IPR040926|mint:P04637|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|rcsb pdb:2AHI|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3Q06|rcsb pdb:3SAK|rcsb pdb:3TG5|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGL|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:5BUA|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6XRE|rcsb pdb:6ZNC|rcsb pdb:7B46|rcsb pdb:7B47|rcsb pdb:7B48|rcsb pdb:7B49|rcsb pdb:7B4A|rcsb pdb:7B4B|rcsb pdb:7B4C|rcsb pdb:7B4D|rcsb pdb:7B4E|rcsb pdb:7B4F|rcsb pdb:7B4G|rcsb pdb:7B4H|rcsb pdb:7B4N|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7DVD|rcsb pdb:7EAX|rcsb pdb:7EDS|rcsb pdb:7EEU|rcsb pdb:7EL4|rcsb pdb:7NMI|rcsb pdb:7RM4|rcsb pdb:7V97|rcsb pdb:7XZX|rcsb pdb:7XZZ|rcsb pdb:7YGI|rcsb pdb:8A31|rcsb pdb:8A32|rcsb pdb:8A92|rcsb pdb:8CG7|rcsb pdb:8DC4|rcsb pdb:8DC6|rcsb pdb:8DC7|rcsb pdb:8DC8|rcsb pdb:8E7A|rcsb pdb:8E7B|rcsb pdb:8F2H|rcsb pdb:8F2I|rcsb pdb:8GCR|rcsb pdb:8HLL|rcsb pdb:8HLM|rcsb pdb:8HLN|rcsb pdb:8J8N|rcsb pdb:8OXM|rcsb pdb:8OXO|rcsb pdb:8QWK|rcsb pdb:8QWL|rcsb pdb:8QWM|rcsb pdb:8QWN|rcsb pdb:8QWO|rcsb pdb:8QWP|rcsb pdb:8R1F|rcsb pdb:8R1G|rcsb pdb:8UQR|rcsb pdb:8WD2|rcsb pdb:8XP5|rcsb pdb:9C5S|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-9723905|reactome:R-HSA-9725370|reactome:R-HSA-9758274|reactome:R-HSA-9819196|reactome:R-HSA-983231|reactome:R-HSA-9833482|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|refseq:NP_001119590.1|refseq:NP_001263624.1|refseq:NP_001263625.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|ensembl:ENSP00000269305.4|ensembl:ENST00000420246.6|ensembl:ENSP00000391127.2|ensembl:ENSP00000391478.2|ensembl:ENST00000455263.6|ensembl:ENSP00000398846.2|ensembl:ENSP00000426252.2|ensembl:ENST00000504290.5|ensembl:ENSP00000484409.1|ensembl:ENST00000504937.5|ensembl:ENSP00000481179.1|ensembl:ENSP00000424104.2|ensembl:ENST00000509690.6|ensembl:ENSP00000425104.2|ensembl:ENST00000510385.5|ensembl:ENSP00000478499.1|ensembl:ENST00000610292.4|ensembl:ENSP00000478219.1|ensembl:ENST00000610538.4|ensembl:ENSP00000480868.1|ensembl:ENST00000619485.4|ensembl:ENSP00000482537.1|ensembl:ENST00000620739.4|ensembl:ENSP00000481638.1|ensembl:ENST00000622645.4|ensembl:ENSP00000482222.1|ensembl:ENSP00000519624.1|ensembl:ENSP00000519626.1|mint:MINT-7557597(identity)"	-	-	-	figure legend:f1b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/02/08	2025/03/31	rogid:jm8ErX3H3EOAYYuSDcddoE/NQx483333	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	intact-crc:B860F0BB2362DFDA|rigid:lz19epTkxyJr2qnuaLk8Bm9lY3o	false	his tag:?-?(MINT-7557594)	-	-	-	"psi-mi:""MI:0816""(molecular weight estimation by staining)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:Q96FW1	uniprotkb:Q56921	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551.2|ensembl:ENSP00000444357.1	intact:EBI-8022937|intact:MINT-7717062	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:q56921_yeren(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Edelmann et al. (2010)	pubmed:20553488|imex:IM-15579|mint:MINT-7717051|doi:10.1111/j.1742-4658.2010.07665|mint:fj-09-1386.r2	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8022950|mint:MINT-7717075|imex:IM-15579-1	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060140.2|ensembl:ENSG00000167770.13(gene)|ensembl:ENST00000428192.6(transcript)|ensembl:ENST00000538426.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0055105""(ubiquitin-protein transferase inhibitor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:2000780""(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N|panther:PTHR12931(orthology-group)|mint:MINT-7717078(identity)"	"interpro:IPR003547(Serine/threonine protein kinase, yersinia)|interpro:IPR019093|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR043119|interpro:IPR043120|mint:Q56921|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|mint:MINT-7717077(identity)"	-	-	comment:mint	figure legend:f3a|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/03/26	2025/03/31	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:RfUY11c0p+R4WZi2FsLmUEh18iU630	intact-crc:3D0A92CE3B9B5090|rigid:RD8ZE9DQpTiR2EM0g+JzqI7GkTc	false	-	mutation decreasing interaction:267-267(MINT-7717097)|flag tag:?-?(MINT-7717094)	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q56921	uniprotkb:Q96FW1	intact:EBI-8022937|intact:MINT-7717062	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551.2|ensembl:ENSP00000444357.1	psi-mi:q56921_yeren(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Edelmann et al. (2010)	pubmed:20553488|imex:IM-15579|mint:MINT-7717051|doi:10.1111/j.1742-4658.2010.07665|mint:fj-09-1386.r2	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8023112|mint:MINT-7717170|imex:IM-15579-2	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003547(Serine/threonine protein kinase, yersinia)|interpro:IPR019093|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR043119|interpro:IPR043120|mint:Q56921|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|mint:MINT-7717172(identity)"	"refseq:NP_060140.2|ensembl:ENSG00000167770.13(gene)|ensembl:ENST00000428192.6(transcript)|ensembl:ENST00000538426.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0055105""(ubiquitin-protein transferase inhibitor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:2000780""(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N|panther:PTHR12931(orthology-group)|mint:MINT-7717173(identity)"	-	comment:mint	-	figure legend:f5a|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/03/26	2025/03/31	rogid:RfUY11c0p+R4WZi2FsLmUEh18iU630	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	intact-crc:3147A45679D4F256|rigid:RD8ZE9DQpTiR2EM0g+JzqI7GkTc	false	flag tag:?-?(MINT-7717175)	mutation increasing interaction:26-26(MINT-7717189)|ha tag:?-?(MINT-7717186)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q96FW1	uniprotkb:Q56921	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551.2|ensembl:ENSP00000444357.1	intact:EBI-8022937|intact:MINT-7717062	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:q56921_yeren(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Edelmann et al. (2010)	pubmed:20553488|imex:IM-15579|mint:MINT-7717051|doi:10.1111/j.1742-4658.2010.07665|mint:fj-09-1386.r2	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8023163|mint:MINT-7717193|imex:IM-15579-3	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060140.2|ensembl:ENSG00000167770.13(gene)|ensembl:ENST00000428192.6(transcript)|ensembl:ENST00000538426.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0055105""(ubiquitin-protein transferase inhibitor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:2000780""(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N|panther:PTHR12931(orthology-group)|mint:MINT-7717195(identity)"	"interpro:IPR003547(Serine/threonine protein kinase, yersinia)|interpro:IPR019093|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR043119|interpro:IPR043120|mint:Q56921|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|mint:MINT-7717201(identity)"	-	-	comment:mint	figure legend:f5a|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/03/26	2025/03/31	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:RfUY11c0p+R4WZi2FsLmUEh18iU630	intact-crc:1000A4FE6BD20635|rigid:RD8ZE9DQpTiR2EM0g+JzqI7GkTc	false	mutation increasing interaction:18-18(MINT-7717196)|ha tag:?-?(MINT-7717198)	flag tag:?-?(MINT-7717202)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q96FW1	uniprotkb:Q56921	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551.2|ensembl:ENSP00000444357.1	intact:EBI-8022937|intact:MINT-7717062	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:q56921_yeren(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Edelmann et al. (2010)	pubmed:20553488|imex:IM-15579|mint:MINT-7717051|doi:10.1111/j.1742-4658.2010.07665|mint:fj-09-1386.r2	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8023227|mint:MINT-7717207|imex:IM-15579-4	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060140.2|ensembl:ENSG00000167770.13(gene)|ensembl:ENST00000428192.6(transcript)|ensembl:ENST00000538426.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0055105""(ubiquitin-protein transferase inhibitor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:2000780""(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N|panther:PTHR12931(orthology-group)|mint:MINT-7717213(identity)"	"interpro:IPR003547(Serine/threonine protein kinase, yersinia)|interpro:IPR019093|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR043119|interpro:IPR043120|mint:Q56921|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|mint:MINT-7717209(identity)"	-	-	comment:mint	figure legend:f5a|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/03/26	2025/03/31	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:RfUY11c0p+R4WZi2FsLmUEh18iU630	intact-crc:9D95D712BBF01244|rigid:RD8ZE9DQpTiR2EM0g+JzqI7GkTc	false	mutation increasing interaction:91-91(MINT-7717216)|ha tag:?-?(MINT-7717214)	flag tag:?-?(MINT-7717210)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q56921	uniprotkb:P61586	intact:EBI-8022937|intact:MINT-7717062	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:q56921_yeren(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Edelmann et al. (2010)	pubmed:20553488|imex:IM-15579|mint:MINT-7717051|doi:10.1111/j.1742-4658.2010.07665|mint:fj-09-1386.r2	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8023311|mint:MINT-7717390|imex:IM-15579-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003547(Serine/threonine protein kinase, yersinia)|interpro:IPR019093|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR043119|interpro:IPR043120|mint:Q56921|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|mint:MINT-7717393(identity)"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1|mint:MINT-7717392(identity)"	-	comment:mint	-	figure legend:f6c|comment:homomint|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/03/26	2025/03/31	rogid:RfUY11c0p+R4WZi2FsLmUEh18iU630	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:41159F6C4DB5E653|rigid:A+G8vzW1PJ+YV6+bjDYmwgm2lZ0	false	flag tag:?-?(MINT-7717400)	myc tag:?-?(MINT-7717407)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q56921	uniprotkb:Q96FW1	intact:EBI-8022937|intact:MINT-7717062	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551.2|ensembl:ENSP00000444357.1	psi-mi:q56921_yeren(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Edelmann et al. (2010)	pubmed:20553488|imex:IM-15579|mint:MINT-7717051|doi:10.1111/j.1742-4658.2010.07665|mint:fj-09-1386.r2	taxid:630(yeren)|taxid:630(Yersinia enterocolitica)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8023311|mint:MINT-7717390|imex:IM-15579-5	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003547(Serine/threonine protein kinase, yersinia)|interpro:IPR019093|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR043119|interpro:IPR043120|mint:Q56921|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|mint:MINT-7717393(identity)"	"refseq:NP_060140.2|ensembl:ENSG00000167770.13(gene)|ensembl:ENST00000428192.6(transcript)|ensembl:ENST00000538426.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0055105""(ubiquitin-protein transferase inhibitor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:2000780""(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N|panther:PTHR12931(orthology-group)|mint:MINT-7717394(identity)"	-	comment:mint	-	figure legend:f6c|comment:homomint|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/03/26	2025/03/31	rogid:RfUY11c0p+R4WZi2FsLmUEh18iU630	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	intact-crc:41159F6C4DB5E653|rigid:A+G8vzW1PJ+YV6+bjDYmwgm2lZ0	false	flag tag:?-?(MINT-7717400)	ha tag:?-?(MINT-7717396)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q96FW1	uniprotkb:Q05608	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551.2|ensembl:ENSP00000444357.1	intact:EBI-8023379|uniprotkb:Q663G6|intact:MINT-7717103	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ypka_yerps(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:pYV0001(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Edelmann et al. (2010)	pubmed:20553488|imex:IM-15579|mint:MINT-7717051|doi:10.1111/j.1742-4658.2010.07665|mint:fj-09-1386.r2	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:273123(yerps)|taxid:273123(Yersinia pseudotuberculosis serotype I)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8023400|mint:MINT-7717124|imex:IM-15579-6	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060140.2|ensembl:ENSG00000167770.13(gene)|ensembl:ENST00000428192.6(transcript)|ensembl:ENST00000538426.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0055105""(ubiquitin-protein transferase inhibitor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:2000780""(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N|panther:PTHR12931(orthology-group)|mint:MINT-7717127(identity)"	"interpro:IPR003547(Serine/threonine protein kinase, yersinia)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:WP_011191359.1|interpro:IPR043119|interpro:IPR043120|mint:Q05608|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|rcsb pdb:2H7O|rcsb pdb:2H7V|mint:MINT-7717126(identity)"	-	-	comment:mint	figure legend:f3b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2010/03/26	2024/11/14	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:EeULntAYipoh/PrBL83OrmGOAEM273123	intact-crc:74369E7C4BC6E9D4|rigid:GxYdSrRm78tgWt9vQabLRNl7eTU	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P62820	uniprotkb:Q5ZSQ3	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	intact:EBI-7632432|intact:MINT-7720716	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	psi-mi:drra_legph(display_long)|uniprotkb:lpg2464(locus name)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)|uniprotkb:sidM(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Suh et al. (2010)	pubmed:19942850|imex:IM-15559|mint:MINT-7720706|doi:10.1038/emboj.2009.347	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7632427|mint:MINT-7720723|imex:IM-15559-8	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)|mint:MINT-7720725(identity)"	"interpro:IPR028057|interpro:IPR048717|interpro:IPR048718|refseq:WP_010948166.1|interpro:IPR033784|interpro:IPR038346|mint:Q5ZSQ3|refseq:YP_096471.1|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0016020""(membrane)|go:""GO:0018117""(protein adenylylation)|go:""GO:0018260""(protein guanylylation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044162""(host cell cytoplasmic vesicle membrane)|go:""GO:0044600""(protein guanylyltransferase activity)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070733""(AMPylase activity)|rcsb pdb:2WWX|rcsb pdb:3JZ9|rcsb pdb:3JZA|rcsb pdb:3L0I|rcsb pdb:3L0M|rcsb pdb:3N6O|rcsb pdb:4MXP|mint:MINT-7720726(identity)"	-	-	comment:mint	comment:mint|figure legend:st1 f1 sf1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/07	2024/11/14	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE272624	intact-crc:F54FF139D4A85F55|rigid:wdWKw5vmrcYEq40S6UQ/7zeb0/4	false	binding-associated region:1-175(MINT-7720735)	binding-associated region:317-545(MINT-7720731)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P62820	uniprotkb:Q5ZSQ3	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	intact:EBI-7632432|intact:MINT-7720716	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	psi-mi:drra_legph(display_long)|uniprotkb:lpg2464(locus name)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)|uniprotkb:sidM(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Suh et al. (2010)	pubmed:19942850|imex:IM-15559|mint:MINT-7720706|doi:10.1038/emboj.2009.347	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7632518|mint:MINT-7720738|imex:IM-15559-5	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)|mint:MINT-7720744(identity)"	"interpro:IPR028057|interpro:IPR048717|interpro:IPR048718|refseq:WP_010948166.1|interpro:IPR033784|interpro:IPR038346|mint:Q5ZSQ3|refseq:YP_096471.1|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0016020""(membrane)|go:""GO:0018117""(protein adenylylation)|go:""GO:0018260""(protein guanylylation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044162""(host cell cytoplasmic vesicle membrane)|go:""GO:0044600""(protein guanylyltransferase activity)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070733""(AMPylase activity)|rcsb pdb:2WWX|rcsb pdb:3JZ9|rcsb pdb:3JZA|rcsb pdb:3L0I|rcsb pdb:3L0M|rcsb pdb:3N6O|rcsb pdb:4MXP|mint:MINT-7720740(identity)"	-	-	comment:mint	comment:mint|figure legend:sf2b f6|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:79.0x10^-9(molar)	2010/04/07	2024/11/14	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE272624	intact-crc:9BFBC0C2BAAC3A51|rigid:wdWKw5vmrcYEq40S6UQ/7zeb0/4	false	binding-associated region:1-175(MINT-7720745)	binding-associated region:317-533(MINT-7720741)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5ZSQ3	uniprotkb:P62820	intact:EBI-7632432|intact:MINT-7720716	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:drra_legph(display_long)|uniprotkb:lpg2464(locus name)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)|uniprotkb:sidM(gene name synonym)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Suh et al. (2010)	pubmed:19942850|imex:IM-15559|mint:MINT-7720706|doi:10.1038/emboj.2009.347	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7632536|mint:MINT-7720756|imex:IM-15559-6	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028057|interpro:IPR048717|interpro:IPR048718|refseq:WP_010948166.1|interpro:IPR033784|interpro:IPR038346|mint:Q5ZSQ3|refseq:YP_096471.1|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0016020""(membrane)|go:""GO:0018117""(protein adenylylation)|go:""GO:0018260""(protein guanylylation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044162""(host cell cytoplasmic vesicle membrane)|go:""GO:0044600""(protein guanylyltransferase activity)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070733""(AMPylase activity)|rcsb pdb:2WWX|rcsb pdb:3JZ9|rcsb pdb:3JZA|rcsb pdb:3L0I|rcsb pdb:3L0M|rcsb pdb:3N6O|rcsb pdb:4MXP|mint:MINT-7720763(identity)"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)|mint:MINT-7720759(identity)"	-	comment:mint	-	figure legend:sf2b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:84.0x10^-9(molar)	2010/04/07	2024/11/14	rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE272624	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:AA1EAC5075DB3BC4|rigid:wdWKw5vmrcYEq40S6UQ/7zeb0/4	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P62820	uniprotkb:Q5ZSQ3	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	intact:EBI-7632432|intact:MINT-7720716	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	psi-mi:drra_legph(display_long)|uniprotkb:lpg2464(locus name)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)|uniprotkb:sidM(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Suh et al. (2010)	pubmed:19942850|imex:IM-15559|mint:MINT-7720706|doi:10.1038/emboj.2009.347	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7632548|mint:MINT-7720885|imex:IM-15559-7	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)|mint:MINT-7720888(identity)"	"interpro:IPR028057|interpro:IPR048717|interpro:IPR048718|refseq:WP_010948166.1|interpro:IPR033784|interpro:IPR038346|mint:Q5ZSQ3|refseq:YP_096471.1|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0016020""(membrane)|go:""GO:0018117""(protein adenylylation)|go:""GO:0018260""(protein guanylylation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044162""(host cell cytoplasmic vesicle membrane)|go:""GO:0044600""(protein guanylyltransferase activity)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070733""(AMPylase activity)|rcsb pdb:2WWX|rcsb pdb:3JZ9|rcsb pdb:3JZA|rcsb pdb:3L0I|rcsb pdb:3L0M|rcsb pdb:3N6O|rcsb pdb:4MXP|mint:MINT-7720892(identity)"	-	-	comment:mint	figure legend:f3b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.4x10^-6(molar)	2010/04/07	2024/11/14	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE272624	intact-crc:547EAA2733F4323D|rigid:wdWKw5vmrcYEq40S6UQ/7zeb0/4	false	binding-associated region:1-175(MINT-7720889)	mutation decreasing interaction:435-435(MINT-7720898)|binding-associated region:317-533(MINT-7720893)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P62820	uniprotkb:Q5ZSQ3	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	intact:EBI-7632432|intact:MINT-7720716	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	psi-mi:drra_legph(display_long)|uniprotkb:lpg2464(locus name)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)|uniprotkb:sidM(gene name synonym)	"psi-mi:""MI:0404""(comigration in non denaturing gel electrophoresis)"	Suh et al. (2010)	pubmed:19942850|imex:IM-15559|mint:MINT-7720706|doi:10.1038/emboj.2009.347	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7632579|mint:MINT-7720792|imex:IM-15559-3	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)|mint:MINT-7720794(identity)"	"interpro:IPR028057|interpro:IPR048717|interpro:IPR048718|refseq:WP_010948166.1|interpro:IPR033784|interpro:IPR038346|mint:Q5ZSQ3|refseq:YP_096471.1|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0016020""(membrane)|go:""GO:0018117""(protein adenylylation)|go:""GO:0018260""(protein guanylylation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044162""(host cell cytoplasmic vesicle membrane)|go:""GO:0044600""(protein guanylyltransferase activity)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070733""(AMPylase activity)|rcsb pdb:2WWX|rcsb pdb:3JZ9|rcsb pdb:3JZA|rcsb pdb:3L0I|rcsb pdb:3L0M|rcsb pdb:3N6O|rcsb pdb:4MXP|mint:MINT-7720798(identity)"	-	-	comment:mint	comment:mint|figure legend:sf5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/07	2024/11/14	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE272624	intact-crc:40257950B0B04170|rigid:wdWKw5vmrcYEq40S6UQ/7zeb0/4	false	-	binding-associated region:317-533(MINT-7720799)	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q5ZSQ3	uniprotkb:P62820	intact:EBI-7632432|intact:MINT-7720716	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:drra_legph(display_long)|uniprotkb:lpg2464(locus name)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)|uniprotkb:sidM(gene name synonym)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0404""(comigration in non denaturing gel electrophoresis)"	Suh et al. (2010)	pubmed:19942850|imex:IM-15559|mint:MINT-7720706|doi:10.1038/emboj.2009.347	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7632593|mint:MINT-7720866|imex:IM-15559-4	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028057|interpro:IPR048717|interpro:IPR048718|refseq:WP_010948166.1|interpro:IPR033784|interpro:IPR038346|mint:Q5ZSQ3|refseq:YP_096471.1|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0016020""(membrane)|go:""GO:0018117""(protein adenylylation)|go:""GO:0018260""(protein guanylylation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044162""(host cell cytoplasmic vesicle membrane)|go:""GO:0044600""(protein guanylyltransferase activity)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070733""(AMPylase activity)|rcsb pdb:2WWX|rcsb pdb:3JZ9|rcsb pdb:3JZA|rcsb pdb:3L0I|rcsb pdb:3L0M|rcsb pdb:3N6O|rcsb pdb:4MXP|mint:MINT-7720870(identity)"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)|mint:MINT-7720868(identity)"	-	comment:mint	-	figure legend:f2d|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/07	2024/11/14	rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE272624	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:F82E34AC587033EE|rigid:wdWKw5vmrcYEq40S6UQ/7zeb0/4	false	binding-associated region:317-533(MINT-7720873)|mutation disrupting interaction:435-435(MINT-7720871)	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q5ZSQ3	uniprotkb:P62820	intact:EBI-7632432|intact:MINT-7720716	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:drra_legph(display_long)|uniprotkb:lpg2464(locus name)|uniprotkb:drrA(gene name)|psi-mi:drrA(display_short)|uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)|uniprotkb:sidM(gene name synonym)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0405""(competition binding)"	Suh et al. (2010)	pubmed:19942850|imex:IM-15559|mint:MINT-7720706|doi:10.1038/emboj.2009.347	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7632620|mint:MINT-7720808|imex:IM-15559-2	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028057|interpro:IPR048717|interpro:IPR048718|refseq:WP_010948166.1|interpro:IPR033784|interpro:IPR038346|mint:Q5ZSQ3|refseq:YP_096471.1|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0016020""(membrane)|go:""GO:0018117""(protein adenylylation)|go:""GO:0018260""(protein guanylylation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0044161""(host cell cytoplasmic vesicle)|go:""GO:0044162""(host cell cytoplasmic vesicle membrane)|go:""GO:0044600""(protein guanylyltransferase activity)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070733""(AMPylase activity)|rcsb pdb:2WWX|rcsb pdb:3JZ9|rcsb pdb:3JZA|rcsb pdb:3L0I|rcsb pdb:3L0M|rcsb pdb:3N6O|rcsb pdb:4MXP|mint:MINT-7720810(identity)"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)|mint:MINT-7720814(identity)"	-	comment:mint	-	comment:mint|figure legend:f2b f2d f3d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/04/07	2024/11/14	rogid:S3OuDt23lHdh6cqJ2Q9JtFivMrE272624	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:4CDC69BAB4CE90E9|rigid:wdWKw5vmrcYEq40S6UQ/7zeb0/4	false	binding-associated region:317-533(MINT-7720811)|mutation decreasing interaction:435-435(MINT-7720860)	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q46342	uniprotkb:P63000	intact:EBI-7213109|intact:MINT-7261718	intact:EBI-413628|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q9BTB4|uniprotkb:Q5JAA8|ensembl:ENSP00000258737.7	psi-mi:tcsl1_parso(display_long)|uniprotkb:tcsL(gene name)|psi-mi:tcsL(display_short)|uniprotkb:Lethal toxin(gene name synonym)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Huelsenbeck et al. (2009)	pubmed:19744486|imex:IM-13830|mint:MINT-7261679|mint:d-09-01249	taxid:1505(closo)|taxid:1505(Clostridium sordellii)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0414""(enzymatic reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7213126|mint:MINT-7261729|imex:IM-13830-1	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020972|interpro:IPR020974|interpro:IPR018337|interpro:IPR024772|interpro:IPR024769|interpro:IPR024770|interpro:IPR038383|interpro:IPR029044|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|rcsb pdb:2VKD|rcsb pdb:2VKH|rcsb pdb:2VL8|mint:Q46342|mint:MINT-7261731(identity)"	"efo:""Orphanet:500159""|ensembl:ENSG00000136238.20(gene)|ensembl:ENST00000348035.9(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006954""(inflammatory response)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009611""(response to wounding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031529""(ruffle organization)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032707""(negative regulation of interleukin-23 production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042470""(melanosome)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045428""(regulation of nitric oxide biosynthetic process)|go:""GO:0045730""(respiratory burst)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048870""(cell motility)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051668""(localization within membrane)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060263""(regulation of respiratory burst)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0097178""(ruffle assembly)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902622""(regulation of neutrophil migration)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:7DPA|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|rcsb pdb:7SJ4|rcsb pdb:7USD|rcsb pdb:7USE|rcsb pdb:8I5V|rcsb pdb:8I5W|rcsb pdb:8Q0N|rcsb pdb:8WEJ|rcsb pdb:8ZJ2|rcsb pdb:8ZJI|rcsb pdb:8ZJJ|rcsb pdb:8ZJK|rcsb pdb:8ZJL|rcsb pdb:8ZJM|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-9748787|reactome:R-HSA-983231|refseq:NP_008839.2|refseq:NP_061485.1|dip:DIP-29260N|panther:PTHR24072(orthology-group)|ensembl:ENSP00000258737.7|ensembl:ENST00000356142.4|ensembl:ENSP00000348461.4|mint:MINT-7261732(identity)"	-	comment:mint	-	figure legend:F4|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/09/03	2025/03/31	rogid:XU+YM2AlKER9o0GRU/CKqnKlfOw1505	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:503B74FB4B076B3A|rigid:g16rkBkljQUlrEjPblBWR8i2Ab4	false	-	glutathione s tranferase tag:?-?(MINT-7261738)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q46342	uniprotkb:P01112	intact:EBI-7213109|intact:MINT-7261718	intact:EBI-350145|uniprotkb:Q9BR65|uniprotkb:Q14080|uniprotkb:Q6FHV9|uniprotkb:B5BUA0|uniprotkb:Q9UCE2|ensembl:ENSP00000309845.7|ensembl:ENSP00000380723.2|ensembl:ENSP00000407586.1|ensembl:ENSP00000480686.1|ensembl:ENSP00000482366.1|ensembl:ENSP00000488757.1	psi-mi:tcsl1_parso(display_long)|uniprotkb:tcsL(gene name)|psi-mi:tcsL(display_short)|uniprotkb:Lethal toxin(gene name synonym)	psi-mi:rash_human(display_long)|uniprotkb:HRAS(gene name)|psi-mi:HRAS(display_short)|uniprotkb:HRAS1(gene name synonym)|uniprotkb:Transforming protein p21(gene name synonym)|uniprotkb:p21ras(gene name synonym)|uniprotkb:H-Ras-1(gene name synonym)|uniprotkb:c-H-ras(gene name synonym)|uniprotkb:Ha-Ras(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Huelsenbeck et al. (2009)	pubmed:19744486|imex:IM-13830|mint:MINT-7261679|mint:d-09-01249	taxid:1505(closo)|taxid:1505(Clostridium sordellii)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0414""(enzymatic reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7213140|mint:MINT-7261742|imex:IM-13830-2	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020972|interpro:IPR020974|interpro:IPR018337|interpro:IPR024772|interpro:IPR024769|interpro:IPR024770|interpro:IPR038383|interpro:IPR029044|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|rcsb pdb:2VKD|rcsb pdb:2VKH|rcsb pdb:2VL8|mint:Q46342|mint:MINT-7261748(identity)"	"efo:""Orphanet:146""|efo:""Orphanet:2612""|efo:""Orphanet:2874""|efo:""Orphanet:3071""|efo:""Orphanet:79414""|ensembl:ENSG00000174775.18(gene)|ensembl:ENSG00000276536.4(gene)|ensembl:ENST00000311189.8(transcript)|ensembl:ENST00000397596.6(transcript)|ensembl:ENST00000451590.5(transcript)|ensembl:ENST00000610977.3(transcript)|ensembl:ENST00000615062.2(transcript)|ensembl:ENST00000631404.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006897""(endocytosis)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0014044""(Schwann cell development)|go:""GO:0019003""(GDP binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034260""(negative regulation of GTPase activity)|go:""GO:0042088""(T-helper 1 type immune response)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042552""(myelination)|go:""GO:0042832""(defense response to protozoan)|go:""GO:0043406""(positive regulation of MAP kinase activity)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060612""(adipose tissue development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0090398""(cellular senescence)|go:""GO:0090402""(oncogene-induced cell senescence)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0098696""(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0160185""(phospholipase C activator activity)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1905360""(GTPase complex)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01112|rcsb pdb:121P|rcsb pdb:1AA9|rcsb pdb:1AGP|rcsb pdb:1BKD|rcsb pdb:1CLU|rcsb pdb:1CRP|rcsb pdb:1CRQ|rcsb pdb:1CRR|rcsb pdb:1CTQ|rcsb pdb:1GNP|rcsb pdb:1GNQ|rcsb pdb:1GNR|rcsb pdb:1HE8|rcsb pdb:1IAQ|rcsb pdb:1IOZ|rcsb pdb:1JAH|rcsb pdb:1JAI|rcsb pdb:1K8R|rcsb pdb:1LF0|rcsb pdb:1LF5|rcsb pdb:1LFD|rcsb pdb:1NVU|rcsb pdb:1NVV|rcsb pdb:1NVW|rcsb pdb:1NVX|rcsb pdb:1P2S|rcsb pdb:1P2T|rcsb pdb:1P2U|rcsb pdb:1P2V|rcsb pdb:1PLJ|rcsb pdb:1PLK|rcsb pdb:1PLL|rcsb pdb:1Q21|rcsb pdb:1QRA|rcsb pdb:1RVD|rcsb pdb:1WQ1|rcsb pdb:1XCM|rcsb pdb:1XD2|rcsb pdb:1XJ0|rcsb pdb:1ZVQ|rcsb pdb:1ZW6|rcsb pdb:221P|rcsb pdb:2C5L|rcsb pdb:2CE2|rcsb pdb:2CL0|rcsb pdb:2CL6|rcsb pdb:2CL7|rcsb pdb:2CLC|rcsb pdb:2CLD|rcsb pdb:2EVW|rcsb pdb:2LCF|rcsb pdb:2LWI|rcsb pdb:2N42|rcsb pdb:2N46|rcsb pdb:2Q21|rcsb pdb:2QUZ|rcsb pdb:2RGA|rcsb pdb:2RGB|rcsb pdb:2RGC|rcsb pdb:2RGD|rcsb pdb:2RGE|rcsb pdb:2RGG|rcsb pdb:2UZI|rcsb pdb:2VH5|rcsb pdb:2X1V|rcsb pdb:3DDC|rcsb pdb:3I3S|rcsb pdb:3K8Y|rcsb pdb:3K9L|rcsb pdb:3K9N|rcsb pdb:3KKM|rcsb pdb:3KKN|rcsb pdb:3KUD|rcsb pdb:3L8Y|rcsb pdb:3L8Z|rcsb pdb:3LBH|rcsb pdb:3LBI|rcsb pdb:3LBN|rcsb pdb:3LO5|rcsb pdb:3OIU|rcsb pdb:3OIV|rcsb pdb:3OIW|rcsb pdb:3RRY|rcsb pdb:3RRZ|rcsb pdb:3RS0|rcsb pdb:3RS2|rcsb pdb:3RS3|rcsb pdb:3RS4|rcsb pdb:3RS5|rcsb pdb:3RS7|rcsb pdb:3RSL|rcsb pdb:3RSO|rcsb pdb:3TGP|rcsb pdb:421P|rcsb pdb:4DLR|rcsb pdb:4DLS|rcsb pdb:4DLT|rcsb pdb:4DLU|rcsb pdb:4DLV|rcsb pdb:4DLW|rcsb pdb:4DLX|rcsb pdb:4DLY|rcsb pdb:4DLZ|rcsb pdb:4DST|rcsb pdb:4DSU|rcsb pdb:4EFL|rcsb pdb:4EFM|rcsb pdb:4EFN|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4K81|rcsb pdb:4L9S|rcsb pdb:4L9W|rcsb pdb:4NYI|rcsb pdb:4NYJ|rcsb pdb:4NYM|rcsb pdb:4Q21|rcsb pdb:4RSG|rcsb pdb:4URU|rcsb pdb:4URV|rcsb pdb:4URW|rcsb pdb:4URX|rcsb pdb:4URY|rcsb pdb:4URZ|rcsb pdb:4US0|rcsb pdb:4US1|rcsb pdb:4US2|rcsb pdb:4XVQ|rcsb pdb:4XVR|rcsb pdb:521P|rcsb pdb:5B2Z|rcsb pdb:5B30|rcsb pdb:5E95|rcsb pdb:5P21|rcsb pdb:5VBE|rcsb pdb:5VBZ|rcsb pdb:5WDO|rcsb pdb:5WDP|rcsb pdb:5WDQ|rcsb pdb:5WFO|rcsb pdb:5WFP|rcsb pdb:5WFQ|rcsb pdb:5WFR|rcsb pdb:5WPL|rcsb pdb:5X9S|rcsb pdb:5ZC6|rcsb pdb:621P|rcsb pdb:6AMB|rcsb pdb:6AXG|rcsb pdb:6BVI|rcsb pdb:6BVJ|rcsb pdb:6BVK|rcsb pdb:6D55|rcsb pdb:6BVL|rcsb pdb:6BVM|rcsb pdb:6CUO|rcsb pdb:6CUP|rcsb pdb:6CUR|rcsb pdb:6D56|rcsb pdb:6D59|rcsb pdb:6D5E|rcsb pdb:6D5G|rcsb pdb:6D5H|rcsb pdb:6D5J|rcsb pdb:6D5L|rcsb pdb:6D5M|rcsb pdb:6D5V|rcsb pdb:6D5W|rcsb pdb:6DZH|rcsb pdb:6E6C|rcsb pdb:6E6P|rcsb pdb:6MQT|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6Q21|rcsb pdb:6V94|rcsb pdb:6V9F|rcsb pdb:6V9J|rcsb pdb:6V9L|rcsb pdb:6V9M|rcsb pdb:6V9N|rcsb pdb:6V9O|rcsb pdb:6ZJ0|rcsb pdb:6ZL3|rcsb pdb:721P|rcsb pdb:7DPH|rcsb pdb:7DPJ|rcsb pdb:7JHP|rcsb pdb:7JIF|rcsb pdb:7JIG|rcsb pdb:7JIH|rcsb pdb:7JII|rcsb pdb:7L0F|rcsb pdb:7L0G|rcsb pdb:7OG9|rcsb pdb:7OGA|rcsb pdb:7OGB|rcsb pdb:7OGC|rcsb pdb:7OGD|rcsb pdb:7OGE|rcsb pdb:7OGF|rcsb pdb:7TAM|rcsb pdb:7VV8|rcsb pdb:8ELV|rcsb pdb:7VV9|rcsb pdb:7VVG|rcsb pdb:821P|rcsb pdb:8BE6|rcsb pdb:8BE7|rcsb pdb:8BE8|rcsb pdb:8BE9|rcsb pdb:8BEA|rcsb pdb:8BOS|rcsb pdb:8BWG|rcsb pdb:8CNJ|rcsb pdb:8CNN|rcsb pdb:8ELK|rcsb pdb:8ELR|rcsb pdb:8ELS|rcsb pdb:8ELT|rcsb pdb:8ELU|rcsb pdb:8ELW|rcsb pdb:8ELX|rcsb pdb:8ELY|rcsb pdb:8ELZ|rcsb pdb:8EM0|rcsb pdb:8FG3|rcsb pdb:8FG4|rcsb pdb:8OSM|rcsb pdb:8OSN|rcsb pdb:8OSO|rcsb pdb:8TBG|rcsb pdb:8TLR|rcsb pdb:8WWC|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-3928662|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5658442|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9753510|reactome:R-HSA-9753512|refseq:NP_001123914.1|refseq:NP_001304983.1|refseq:NP_005334.1|refseq:NP_789765.1|dip:DIP-1050N|panther:PTHR24070(orthology-group)|ensembl:ENSP00000309845.7|ensembl:ENST00000397594.7|ensembl:ENSP00000380722.3|ensembl:ENSP00000380723.2|ensembl:ENST00000417302.7|ensembl:ENSP00000388246.1|ensembl:ENSP00000407586.1|ensembl:ENST00000493230.5|ensembl:ENSP00000434023.1|ensembl:ENSP00000480686.1|ensembl:ENSP00000482366.1|ensembl:ENST00000616241.4|ensembl:ENSP00000480317.1|ensembl:ENSP00000488757.1|ensembl:ENST00000631967.1|ensembl:ENSP00000488225.1|ensembl:ENST00000634098.1|ensembl:ENSP00000488296.1|mint:MINT-7261744(identity)"	-	comment:mint	-	figure legend:F4|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/09/03	2025/03/31	rogid:XU+YM2AlKER9o0GRU/CKqnKlfOw1505	rogid:hjBAnRVG6bLFePkCYnkl3ZCjnmw9606	intact-crc:78B1DA25D2D0B55E|rigid:rPN/xWdL5XpSS6fUTXV+SCX0hGc	false	-	glutathione s tranferase tag:?-?(MINT-7261745)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q46342	uniprotkb:P01116	intact:EBI-7213109|intact:MINT-7261718	intact:EBI-367415|uniprotkb:P01118|uniprotkb:Q96D10|uniprotkb:B0LPF9|uniprotkb:A8K8Z5|ensembl:ENSP00000256078.5	psi-mi:tcsl1_parso(display_long)|uniprotkb:tcsL(gene name)|psi-mi:tcsL(display_short)|uniprotkb:Lethal toxin(gene name synonym)	psi-mi:rask_human(display_long)|uniprotkb:KRAS(gene name)|psi-mi:KRAS(display_short)|uniprotkb:RASK2(gene name synonym)|uniprotkb:KRAS2(gene name synonym)|uniprotkb:K-Ras 2(gene name synonym)|uniprotkb:Ki-Ras(gene name synonym)|uniprotkb:c-K-ras(gene name synonym)|uniprotkb:c-Ki-ras(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Huelsenbeck et al. (2009)	pubmed:19744486|imex:IM-13830|mint:MINT-7261679|mint:d-09-01249	taxid:1505(closo)|taxid:1505(Clostridium sordellii)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0414""(enzymatic reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7213154|mint:MINT-7261772|imex:IM-13830-3	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020972|interpro:IPR020974|interpro:IPR018337|interpro:IPR024772|interpro:IPR024769|interpro:IPR024770|interpro:IPR038383|interpro:IPR029044|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|rcsb pdb:2VKD|rcsb pdb:2VKH|rcsb pdb:2VL8|mint:Q46342|mint:MINT-7261778(identity)"	"efo:""Orphanet:1333""|efo:""Orphanet:1340""|efo:""Orphanet:144""|efo:""Orphanet:146""|efo:""Orphanet:2396""|efo:""Orphanet:251615""|efo:""Orphanet:2612""|efo:""Orphanet:268114""|efo:""Orphanet:3339""|efo:""Orphanet:648""|efo:""Orphanet:86834""|ensembl:ENSG00000133703.14(gene)|ensembl:ENST00000256078.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0008542""(visual learning)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010467""(gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019003""(GDP binding)|go:""GO:0021897""(forebrain astrocyte development)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030857""(negative regulation of epithelial cell differentiation)|go:""GO:0032228""(regulation of synaptic transmission, GABAergic)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060441""(epithelial tube branching involved in lung morphogenesis)|go:""GO:0060509""(type I pneumocyte differentiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01116|rcsb pdb:1D8D|rcsb pdb:1D8E|rcsb pdb:1KZO|rcsb pdb:1KZP|rcsb pdb:1N4P|rcsb pdb:1N4Q|rcsb pdb:1N4R|rcsb pdb:1N4S|rcsb pdb:2MSC|rcsb pdb:2MSD|rcsb pdb:2MSE|rcsb pdb:3GFT|rcsb pdb:4DSN|rcsb pdb:4DSO|rcsb pdb:4EPR|rcsb pdb:4EPT|rcsb pdb:4EPV|rcsb pdb:4EPW|rcsb pdb:4EPX|rcsb pdb:4EPY|rcsb pdb:4L8G|rcsb pdb:4LDJ|rcsb pdb:4LPK|rcsb pdb:4LRW|rcsb pdb:4LUC|rcsb pdb:4LV6|rcsb pdb:4LYF|rcsb pdb:4LYH|rcsb pdb:4LYJ|rcsb pdb:4M1O|rcsb pdb:4M1S|rcsb pdb:4M1T|rcsb pdb:4M1W|rcsb pdb:4M1Y|rcsb pdb:4M21|rcsb pdb:4M22|rcsb pdb:4NMM|rcsb pdb:4OBE|rcsb pdb:4PZY|rcsb pdb:4PZZ|rcsb pdb:4Q01|rcsb pdb:4Q02|rcsb pdb:4Q03|rcsb pdb:4QL3|rcsb pdb:4TQ9|rcsb pdb:4TQA|rcsb pdb:4WA7|rcsb pdb:5F2E|rcsb pdb:5KYK|rcsb pdb:5MLA|rcsb pdb:5MLB|rcsb pdb:5O2S|rcsb pdb:5O2T|rcsb pdb:5OCG|rcsb pdb:5OCO|rcsb pdb:5OCT|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5UFE|rcsb pdb:5UFQ|rcsb pdb:5UK9|rcsb pdb:5UQW|rcsb pdb:5US4|rcsb pdb:5USJ|rcsb pdb:5V6S|rcsb pdb:5V6V|rcsb pdb:5V71|rcsb pdb:5V9L|rcsb pdb:5V9O|rcsb pdb:5V9U|rcsb pdb:5VBM|rcsb pdb:5VP7|rcsb pdb:5VPI|rcsb pdb:5VPY|rcsb pdb:5VPZ|rcsb pdb:5VQ0|rcsb pdb:5VQ1|rcsb pdb:5VQ2|rcsb pdb:5VQ6|rcsb pdb:5VQ8|rcsb pdb:5W22|rcsb pdb:5WHA|rcsb pdb:5WHB|rcsb pdb:5WHD|rcsb pdb:5WHE|rcsb pdb:5WLB|rcsb pdb:5WPM|rcsb pdb:5XCO|rcsb pdb:5YXZ|rcsb pdb:5YY1|rcsb pdb:6ARK|rcsb pdb:6ASA|rcsb pdb:6ASE|rcsb pdb:6B0V|rcsb pdb:6B0Y|rcsb pdb:6BOF|rcsb pdb:6BP1|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CU6|rcsb pdb:6E6F|rcsb pdb:6E6G|rcsb pdb:6EPL|rcsb pdb:6EPM|rcsb pdb:6EPN|rcsb pdb:6EPO|rcsb pdb:6EPP|rcsb pdb:6F76|rcsb pdb:6FA1|rcsb pdb:6FA2|rcsb pdb:6FA3|rcsb pdb:6FA4|rcsb pdb:6GJ5|rcsb pdb:6GJ6|rcsb pdb:6GJ7|rcsb pdb:6GJ8|rcsb pdb:6GOD|rcsb pdb:6GOE|rcsb pdb:6GOF|rcsb pdb:6GOG|rcsb pdb:6GOM|rcsb pdb:6GQT|rcsb pdb:6GQW|rcsb pdb:6GQX|rcsb pdb:6GQY|rcsb pdb:6H46|rcsb pdb:6H47|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6M9W|rcsb pdb:6MBQ|rcsb pdb:6MBT|rcsb pdb:6MBU|rcsb pdb:6MNX|rcsb pdb:6MQG|rcsb pdb:6MQN|rcsb pdb:6MS9|rcsb pdb:6MTA|rcsb pdb:6N2J|rcsb pdb:6N2K|rcsb pdb:6O36|rcsb pdb:6O46|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6OB2|rcsb pdb:6OB3|rcsb pdb:6OIM|rcsb pdb:6P0Z|rcsb pdb:6P8W|rcsb pdb:6P8X|rcsb pdb:6P8Y|rcsb pdb:6P8Z|rcsb pdb:6PGO|rcsb pdb:6PGP|rcsb pdb:6PQ3|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6QUU|rcsb pdb:6QUV|rcsb pdb:6QUW|rcsb pdb:6QUX|rcsb pdb:6T5B|rcsb pdb:6T5U|rcsb pdb:6T5V|rcsb pdb:6TAM|rcsb pdb:6TAN|rcsb pdb:6USX|rcsb pdb:6USZ|rcsb pdb:6UT0|rcsb pdb:6V5L|rcsb pdb:6V65|rcsb pdb:6V6F|rcsb pdb:6VC8|rcsb pdb:6VJJ|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:6WGN|rcsb pdb:6WS2|rcsb pdb:6WS4|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6YR8|rcsb pdb:6YXW|rcsb pdb:6ZL5|rcsb pdb:6ZLI|rcsb pdb:7A1W|rcsb pdb:7A1X|rcsb pdb:7A1Y|rcsb pdb:7A47|rcsb pdb:7ACA|rcsb pdb:7ACF|rcsb pdb:7ACH|rcsb pdb:7ACQ|rcsb pdb:7C40|rcsb pdb:7C41|rcsb pdb:7EW9|rcsb pdb:7EWA|rcsb pdb:7EWB|rcsb pdb:7EYX|rcsb pdb:7F0W|rcsb pdb:7KFZ|rcsb pdb:7KMR|rcsb pdb:7KYZ|rcsb pdb:7LC1|rcsb pdb:7LC2|rcsb pdb:7LGI|rcsb pdb:7LZ5|rcsb pdb:7MDP|rcsb pdb:7MQU|rcsb pdb:7NY8|rcsb pdb:7O70|rcsb pdb:7OK3|rcsb pdb:7OK4|rcsb pdb:7OO7|rcsb pdb:7Q9U|rcsb pdb:7R0M|rcsb pdb:7R0N|rcsb pdb:7R0Q|rcsb pdb:7ROV|rcsb pdb:7RP2|rcsb pdb:7RP3|rcsb pdb:7RP4|rcsb pdb:7RPZ|rcsb pdb:7RSC|rcsb pdb:7RSE|rcsb pdb:7RT1|rcsb pdb:7RT2|rcsb pdb:7RT3|rcsb pdb:7RT4|rcsb pdb:7RT5|rcsb pdb:7SCW|rcsb pdb:7SCX|rcsb pdb:7STF|rcsb pdb:7T1F|rcsb pdb:7T47|rcsb pdb:7TLE|rcsb pdb:7TLG|rcsb pdb:7TLK|rcsb pdb:7U8H|rcsb pdb:7VVB|rcsb pdb:7W5R|rcsb pdb:7YCC|rcsb pdb:7YCE|rcsb pdb:7YUZ|rcsb pdb:7YV1|rcsb pdb:8AFB|rcsb pdb:8AFC|rcsb pdb:8AFD|rcsb pdb:8AQ5|rcsb pdb:8AQ7|rcsb pdb:8AZR|rcsb pdb:8AZV|rcsb pdb:8AZX|rcsb pdb:8AZY|rcsb pdb:8AZZ|rcsb pdb:8B00|rcsb pdb:8B69|rcsb pdb:8B6I|rcsb pdb:8B78|rcsb pdb:8BE3|rcsb pdb:8BE4|rcsb pdb:8BE5|rcsb pdb:8BLR|rcsb pdb:8CPR|rcsb pdb:8CX5|rcsb pdb:8DGS|rcsb pdb:8DGT|rcsb pdb:8DNI|rcsb pdb:8DNJ|rcsb pdb:8DNK|rcsb pdb:8DVG|rcsb pdb:8EBZ|rcsb pdb:8ECR|rcsb pdb:8EDY|rcsb pdb:8EER|rcsb pdb:8EIE|rcsb pdb:8EPW|rcsb pdb:8EZG|rcsb pdb:8F0M|rcsb pdb:8FMI|rcsb pdb:8FMJ|rcsb pdb:8FMK|rcsb pdb:8G42|rcsb pdb:8G47|rcsb pdb:8G4F|rcsb pdb:8G4H|rcsb pdb:8G9P|rcsb pdb:8G9Q|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8JGD|rcsb pdb:8JHL|rcsb pdb:8JJS|rcsb pdb:8ONV|rcsb pdb:8PI0|rcsb pdb:8QU8|rcsb pdb:8QUG|rcsb pdb:8QVU|rcsb pdb:8QW6|rcsb pdb:8QW7|rcsb pdb:8R7W|rcsb pdb:8R7X|rcsb pdb:8S8C|rcsb pdb:8STM|rcsb pdb:8STN|rcsb pdb:8T4V|rcsb pdb:8T71|rcsb pdb:8T72|rcsb pdb:8T73|rcsb pdb:8T74|rcsb pdb:8T75|rcsb pdb:8TBF|rcsb pdb:8TBH|rcsb pdb:8TBJ|rcsb pdb:8TBK|rcsb pdb:8TBL|rcsb pdb:8TBM|rcsb pdb:8TBN|rcsb pdb:8TVK|rcsb pdb:8TXE|rcsb pdb:8TXG|rcsb pdb:8TXH|rcsb pdb:8TXJ|rcsb pdb:8TXK|rcsb pdb:8TY2|rcsb pdb:8TY8|rcsb pdb:8TY9|rcsb pdb:8UDR|rcsb pdb:8UN3|rcsb pdb:8UN4|rcsb pdb:8UN5|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8X6R|rcsb pdb:9AX6|rcsb pdb:9BFY|rcsb pdb:9BG1|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-4086398|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5658442|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-8951936|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9753510|reactome:R-HSA-9753512|refseq:NP_004976.2|refseq:NP_203524.1|refseq:XP_006719132.1|refseq:XP_011518955.1|dip:DIP-33951N|panther:PTHR24070(orthology-group)|ensembl:ENSP00000256078.5|ensembl:ENST00000311936.8|ensembl:ENSP00000308495.3|ensembl:ENST00000685328.1|ensembl:ENSP00000508921.1|ensembl:ENST00000688940.1|ensembl:ENSP00000509238.1|mint:MINT-7261774(identity)"	-	comment:mint	-	figure legend:F4|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/09/03	2025/03/31	rogid:XU+YM2AlKER9o0GRU/CKqnKlfOw1505	rogid:ujXYEgifbSf/thk1UOTW7sKWkX89606	intact-crc:D002EED69DA864F5|rigid:4i4J5xT/mkA2P2isFbWQSj2E2sA	false	-	glutathione s tranferase tag:?-?(MINT-7261775)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q46342	uniprotkb:P01111	intact:EBI-7213109|intact:MINT-7261718	intact:EBI-721993|uniprotkb:Q14971|uniprotkb:Q15104|uniprotkb:Q15282|ensembl:ENSP00000358548.4	psi-mi:tcsl1_parso(display_long)|uniprotkb:tcsL(gene name)|psi-mi:tcsL(display_short)|uniprotkb:Lethal toxin(gene name synonym)	psi-mi:rasn_human(display_long)|uniprotkb:Transforming protein N-Ras(gene name synonym)|uniprotkb:NRAS(gene name)|psi-mi:NRAS(display_short)|uniprotkb:HRAS1(gene name synonym)	"psi-mi:""MI:0415""(enzymatic study)"	Huelsenbeck et al. (2009)	pubmed:19744486|imex:IM-13830|mint:MINT-7261679|mint:d-09-01249	taxid:1505(closo)|taxid:1505(Clostridium sordellii)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0414""(enzymatic reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7213168|mint:MINT-7261784|imex:IM-13830-4	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020972|interpro:IPR020974|interpro:IPR018337|interpro:IPR024772|interpro:IPR024769|interpro:IPR024770|interpro:IPR038383|interpro:IPR029044|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|rcsb pdb:2VKD|rcsb pdb:2VKH|rcsb pdb:2VL8|mint:Q46342|mint:MINT-7261790(identity)"	"efo:""Orphanet:146""|efo:""Orphanet:2612""|efo:""Orphanet:268114""|efo:""Orphanet:389""|efo:""Orphanet:626""|efo:""Orphanet:648""|efo:""Orphanet:86834""|ensembl:ENSG00000213281.5(gene)|ensembl:ENST00000369535.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0019003""(GDP binding)|go:""GO:0044877""(protein-containing complex binding)|rcsb pdb:6MPP|go:""GO:0045445""(myoblast differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01111|rcsb pdb:2N9C|rcsb pdb:3CON|rcsb pdb:5UHV|rcsb pdb:6E6H|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6WGH|rcsb pdb:6ZIO|rcsb pdb:6ZIR|rcsb pdb:6ZIZ|rcsb pdb:7F68|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7PB2|rcsb pdb:8TBI|rcsb pdb:8VM2|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5658442|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9753510|reactome:R-HSA-9753512|refseq:NP_002515.1|dip:DIP-1058N|panther:PTHR24070(orthology-group)|ensembl:ENSP00000358548.4|mint:MINT-7261786(identity)"	-	comment:mint	-	figure legend:F4|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/09/03	2025/03/31	rogid:XU+YM2AlKER9o0GRU/CKqnKlfOw1505	rogid:Et90BD+t6LnYThbW6ShQge1GRK89606	intact-crc:DB09A7F20015C4F7|rigid:Y2nYqaqNJAY63yY+1vOzVqdY6BM	false	-	glutathione s tranferase tag:?-?(MINT-7261787)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q86YH6	uniprotkb:P0AD57	intact:EBI-7701365|uniprotkb:Q33DR4|uniprotkb:Q5VU39|intact:MINT-6778201|uniprotkb:Q4G158|uniprotkb:Q9NR58|uniprotkb:Q5VU38|ensembl:ENSP00000358033.4	intact:EBI-1131851|uniprotkb:P19641|uniprotkb:Q2M925	psi-mi:dlp1_human(display_long)|uniprotkb:Decaprenyl-diphosphate synthase subunit 2(gene name synonym)|uniprotkb:Solanesyl-diphosphate synthase subunit 2(gene name synonym)|uniprotkb:All-trans-decaprenyl-diphosphate synthase subunit 2(gene name synonym)|uniprotkb:Decaprenyl pyrophosphate synthase subunit 2(gene name synonym)|uniprotkb:PDSS2(gene name)|psi-mi:PDSS2(display_short)|uniprotkb:C6orf210(gene name synonym)|uniprotkb:DLP1(gene name synonym)|uniprotkb:Candidate tumor suppressor protein(gene name synonym)	psi-mi:ispb_ecoli(display_long)|uniprotkb:yhbD(gene name synonym)|uniprotkb:Octaprenyl pyrophosphate synthase(gene name synonym)|uniprotkb:ispB(gene name)|psi-mi:ispB(display_short)|uniprotkb:cel(gene name synonym)|uniprotkb:b3187(locus name)|uniprotkb:JW3154(locus name)|uniprotkb:All-trans-octaprenyl-diphosphate synthase(gene name synonym)	"psi-mi:""MI:0276""(blue native page)"	Cui et al. (2010)	pubmed:20051244|imex:IM-15459|mint:MINT-7384991|mint:d-09-02181	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7701398|mint:MINT-7385426|imex:IM-15459-7	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011534265.1|refseq:NP_065114.3|ensembl:ENSG00000164494.12(gene)|ensembl:ENST00000369037.9(transcript)|go:""GO:0004659""(prenyltransferase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0008299""(isoprenoid biosynthetic process)|go:""GO:0021549""(cerebellum development)|go:""GO:0032476""(polyprenyl diphosphate synthase complex)|go:""GO:0032478""(heterotetrameric polyprenyl diphosphate synthase complex)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050878""(regulation of body fluid levels)|go:""GO:0052923""(""all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity"")|go:""GO:0097269""(all-trans-decaprenyl-diphosphate synthase activity)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|mint:Q86YH6|reactome:R-HSA-2142789|panther:PTHR12001(orthology-group)|ensembl:ENST00000369031.4|ensembl:ENSP00000358027.4|ensembl:ENSP00000358033.4|mint:MINT-7385428(identity)"	"go:""GO:0004659""(prenyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0008299""(isoprenoid biosynthetic process)|go:""GO:0016094""(polyprenol biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0106350""(all-trans-octaprenyl-diphosphate synthase activity)|rcsb pdb:5ZE6|rcsb pdb:5ZLF|refseq:NP_417654.1|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|mint:P0AD57|refseq:WP_001047336.1|interpro:IPR033749|panther:PTHR12001(orthology-group)|mint:MINT-7385432(identity)"	-	comment:mint|function:Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10|comment:homomint	-	figure legend:f5b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/12/16	2025/02/11	rogid:EbLdtaxYD7Z8iEnSxIsu6EBB7IA9606	rogid:L2DtRCLaId3q4tHOQhRJiul01ew83333	intact-crc:733527FC1C1F383A|rigid:Sg7b5jdeLgVMhWicBEVBZ2QLODo	false	his tag:?-?(MINT-7385429)	glutathione s tranferase tag:?-?(MINT-7385433)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0815""(confirmation by molecular weight)"
uniprotkb:B5Z6S0	uniprotkb:O43318	intact:EBI-7287204|intact:MINT-7297600	intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335.3	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Lamb et al. (2009)	pubmed:19820695|imex:IM-13889|mint:MINT-7297592|doi:10.1038/embor.2009.210	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7287380|mint:MINT-7297644|imex:IM-13889-4	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149|mint:MINT-7297650(identity)"	"ensembl:ENSG00000135341.19(gene)|ensembl:ENST00000369329.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0005114""(type II transforming growth factor beta receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007252""(I-kappaB phosphorylation)|go:""GO:0007254""(JNK cascade)|go:""GO:0008349""(MAP kinase kinase kinase kinase activity)|go:""GO:0010008""(endosome membrane)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0034138""(toll-like receptor 3 signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035173""(histone kinase activity)|go:""GO:0035666""(TRIF-dependent toll-like receptor signaling pathway)|go:""GO:0035872""(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0038172""(interleukin-33-mediated signaling pathway)|go:""GO:0038173""(interleukin-17A-mediated signaling pathway)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043276""(anoikis)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045793""(positive regulation of cell size)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140672""(ATAC complex)|go:""GO:0141111""(positive regulation of cGAS/STING signaling pathway)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904754""(positive regulation of vascular associated smooth muscle cell migration)|go:""GO:1990450""(linear polyubiquitin binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR049637|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|rcsb pdb:8GW3|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-9705671|reactome:R-HSA-975163|refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|dip:DIP-27523N|efo:""Orphanet:1826""|efo:""Orphanet:3238""|panther:PTHR46716(orthology-group)|mint:MINT-7297646(identity)"	-	comment:mint	-	figure legend:f4b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-ags)|taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)	-	2009/11/09	2025/03/26	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606	intact-crc:17C7C138DDDE8F84|rigid:Eop0w7MCyzjFKIwOZY0Wnpo3OF8	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:O43318	uniprotkb:B5Z6S0	intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335.3	intact:EBI-7287204|intact:MINT-7297600	psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym)	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	"psi-mi:""MI:0096""(pull down)"	Lamb et al. (2009)	pubmed:19820695|imex:IM-13889|mint:MINT-7297592|doi:10.1038/embor.2009.210	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7287432|mint:MINT-7297681|imex:IM-13889-1	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000135341.19(gene)|ensembl:ENST00000369329.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0005114""(type II transforming growth factor beta receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007252""(I-kappaB phosphorylation)|go:""GO:0007254""(JNK cascade)|go:""GO:0008349""(MAP kinase kinase kinase kinase activity)|go:""GO:0010008""(endosome membrane)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0034138""(toll-like receptor 3 signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035173""(histone kinase activity)|go:""GO:0035666""(TRIF-dependent toll-like receptor signaling pathway)|go:""GO:0035872""(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0038172""(interleukin-33-mediated signaling pathway)|go:""GO:0038173""(interleukin-17A-mediated signaling pathway)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043276""(anoikis)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045793""(positive regulation of cell size)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140672""(ATAC complex)|go:""GO:0141111""(positive regulation of cGAS/STING signaling pathway)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904754""(positive regulation of vascular associated smooth muscle cell migration)|go:""GO:1990450""(linear polyubiquitin binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR049637|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|rcsb pdb:8GW3|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-9705671|reactome:R-HSA-975163|refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|dip:DIP-27523N|efo:""Orphanet:1826""|efo:""Orphanet:3238""|panther:PTHR46716(orthology-group)|mint:MINT-7297687(identity)"	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149|mint:MINT-7297683(identity)"	-	-	comment:mint	comment:mint|comment:TAK1 taxid has not been specified.|figure legend:sf9 sf10 sf11|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/09	2025/03/31	rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	intact-crc:693C33FB27477CA6|rigid:Eop0w7MCyzjFKIwOZY0Wnpo3OF8	false	binding-associated region:1-454(MINT-7297702)|flag tag:?-?(MINT-7297688)	binding-associated region:1-193(MINT-7297699)|glutathione s tranferase tag:?-?(MINT-7297684)	-	-	"psi-mi:""MI:0821""(molecular weight estimation by autoradiography)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:B5Z6S0	uniprotkb:O43318	intact:EBI-7287204|intact:MINT-7297600	intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335.3	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Lamb et al. (2009)	pubmed:19820695|imex:IM-13889|mint:MINT-7297592|doi:10.1038/embor.2009.210	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7287456|mint:MINT-7297707|imex:IM-13889-2	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149|mint:MINT-7297709(identity)"	"ensembl:ENSG00000135341.19(gene)|ensembl:ENST00000369329.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0005114""(type II transforming growth factor beta receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007252""(I-kappaB phosphorylation)|go:""GO:0007254""(JNK cascade)|go:""GO:0008349""(MAP kinase kinase kinase kinase activity)|go:""GO:0010008""(endosome membrane)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0034138""(toll-like receptor 3 signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035173""(histone kinase activity)|go:""GO:0035666""(TRIF-dependent toll-like receptor signaling pathway)|go:""GO:0035872""(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0038172""(interleukin-33-mediated signaling pathway)|go:""GO:0038173""(interleukin-17A-mediated signaling pathway)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043276""(anoikis)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045793""(positive regulation of cell size)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140672""(ATAC complex)|go:""GO:0141111""(positive regulation of cGAS/STING signaling pathway)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904754""(positive regulation of vascular associated smooth muscle cell migration)|go:""GO:1990450""(linear polyubiquitin binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR049637|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|rcsb pdb:8GW3|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-9705671|reactome:R-HSA-975163|refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|dip:DIP-27523N|efo:""Orphanet:1826""|efo:""Orphanet:3238""|panther:PTHR46716(orthology-group)|mint:MINT-7297715(identity)"	-	comment:mint	-	comment:mint|comment:TAK1 taxid has not been specified.|figure legend:sf9 sf10 sf11|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/09	2025/03/31	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606	intact-crc:6596C3867132C285|rigid:Eop0w7MCyzjFKIwOZY0Wnpo3OF8	false	binding-associated region:1-193(MINT-7297710)|glutathione s tranferase tag:?-?(MINT-7297712)	binding-associated region:?-?(MINT-7297716)|flag tag:?-?(MINT-7297718)	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0821""(molecular weight estimation by autoradiography)"
uniprotkb:Q9Y4K3	uniprotkb:B5Z6S0	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|uniprotkb:D3DR16|ensembl:ENSP00000337853.5|ensembl:ENSP00000433623.1	intact:EBI-7287204|intact:MINT-7297600	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:b5z6s0_helpg(display_long)|uniprotkb:cagA(gene name)|psi-mi:cagA(display_short)|uniprotkb:HPG27_507(locus name)	"psi-mi:""MI:0096""(pull down)"	Lamb et al. (2009)	pubmed:19820695|imex:IM-13889|mint:MINT-7297592|doi:10.1038/embor.2009.210	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:563041(helpg)|taxid:563041(""Helicobacter pylori (strain G27)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7287493|mint:MINT-7297754|imex:IM-13889-3	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1810""|ensembl:ENSG00000175104.15(gene)|ensembl:ENST00000348124.5(transcript)|ensembl:ENST00000526995.6(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001503""(ossification)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001843""(neural tube closure)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002637""(regulation of immunoglobulin production)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006974""(DNA damage response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0031666""(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032147""(activation of protein kinase activity)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034138""(toll-like receptor 3 signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0034450""(ubiquitin-ubiquitin ligase activity)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0035666""(TRIF-dependent toll-like receptor signaling pathway)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0038172""(interleukin-33-mediated signaling pathway)|go:""GO:0038173""(interleukin-17A-mediated signaling pathway)|go:""GO:0042088""(T-helper 1 type immune response)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043011""(myeloid dendritic cell differentiation)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043422""(protein kinase B binding)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0045087""(innate immune response)|go:""GO:0045453""(bone resorption)|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0097400""(interleukin-17-mediated signaling pathway)|go:""GO:0098696""(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0141198""(protein branched polyubiquitination)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000679""(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|interpro:IPR037309|interpro:IPR041310|interpro:IPR049342|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|rcsb pdb:7L3L|rcsb pdb:8HZ2|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-9692916|reactome:R-HSA-9705671|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-9758274|reactome:R-HSA-975871|refseq:NP_004611.1|refseq:NP_665802.1|dip:DIP-27515N|panther:PTHR10131(orthology-group)|mint:MINT-7297762(identity)"	"interpro:IPR045157|interpro:IPR004355(Type IV secretion system CagA exotoxin)|interpro:IPR005169(CagA exotoxin)|mint:B5Z6S0|refseq:WP_000180783.1|go:""GO:0019534""(toxin transmembrane transporter activity)|interpro:IPR047149|mint:MINT-7297756(identity)"	-	-	comment:mint	comment:mint|comment:proteins taxid has not been specified.|figure legend:sf20|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/09	2025/03/31	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	rogid:Nrfu7qaUVVn87zjUSC+iNqm0PxI563041	intact-crc:2F0C5B28219C464F|rigid:FCbcybDWPMNtpaTt1rHZuLNdb98	false	-	glutathione s tranferase tag:?-?(MINT-7297759)	-	-	"psi-mi:""MI:0821""(molecular weight estimation by autoradiography)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:P39656	uniprotkb:Q5NGF9	intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457.3|uniprotkb:B4DJE3|uniprotkb:B4DLI2	intact:EBI-2796712|uniprotkb:A0A0G2RMW7	psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name)	psi-mi:q5ngf9_fratt(display_long)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:FTT_0886(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804073|imex:IM-13779-768	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000244038.11(gene)|ensembl:ENST00000415136.6(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0034097""(response to cytokine)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042110""(T cell activation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548|refseq:NP_005207.2|efo:""Orphanet:300536""|panther:PTHR10830(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|refseq:YP_169883.1|interpro:IPR027417|refseq:WP_003020876.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606	rogid:OSkw64bDGErXabpL9In6RSfdCEQ177416	intact-crc:4CF32F5E0D1EDC68|rigid:CP/yIlZrU48PAOkQWV8HDUrK6j4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFP9	uniprotkb:Q96SU4	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	intact:EBI-2511368|ensembl:ENSP00000407168.1|uniprotkb:Q6IA67|uniprotkb:Q9H9X2|uniprotkb:Q96SK4|uniprotkb:B1AKJ8|uniprotkb:Q5TFC0|uniprotkb:Q8NB17|uniprotkb:Q8TAS8|uniprotkb:D3DQ31|uniprotkb:B3KPQ4|uniprotkb:Q86YQ3	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	psi-mi:osbl9_human(display_long)|uniprotkb:OSBPL9(gene name)|psi-mi:OSBPL9(display_short)|uniprotkb:ORP9(gene name synonym)|uniprotkb:OSBP4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804093|imex:IM-13779-769	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	"ensembl:ENSG00000117859.19(gene)|ensembl:ENST00000428468.6(transcript)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032934""(sterol binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0120015""(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q96SU4|reactome:R-HSA-192105|refseq:XP_011538905.1|refseq:XP_011538906.1|refseq:NP_078862.4|refseq:NP_683702.1|refseq:NP_683703.1|refseq:NP_683705.1|refseq:NP_683706.3|refseq:NP_683704.2|refseq:NP_683707.3|refseq:XP_006710386.1|refseq:XP_006710387.1|refseq:XP_006710388.1|refseq:XP_006710389.1|refseq:NP_001317509.1|refseq:XP_016855708.1|refseq:XP_016855709.1|refseq:XP_016855710.1|panther:PTHR10972(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	rogid:2XLQ0JD4BEKGoyiwd/63YTmyVlE9606	intact-crc:6806A84A2EB2A10B|rigid:B1QHhgZolaUzzXUAt+fBAkxr760	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13438	uniprotkb:Q5NG89	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|uniprotkb:E7EW91|uniprotkb:G3XA88|ensembl:ENSP00000318165.7	intact:EBI-2804121|uniprotkb:A0A0G2RNT2	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:q5ng89_fratt(display_long)|uniprotkb:aroG(gene name)|psi-mi:aroG(display_short)|uniprotkb:FTT_0963c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804125|imex:IM-13779-771	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|dip:DIP-37493N|ensembl:ENSG00000135506.17(gene)|ensembl:ENST00000315970.12(transcript)|go:""GO:0000836""(Hrd1p ubiquitin ligase complex)|go:""GO:0002020""(protease binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006605""(protein targeting)|go:""GO:0006621""(protein retention in ER lumen)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:1904153""(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|interpro:IPR045149|mint:Q13438|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|panther:PTHR15414(orthology-group)"	"interpro:IPR006219(DHAP synthase, class 1)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR006218(DAHP synthetase I/KDSA)|refseq:YP_169953.1|rcsb pdb:3TQK|go:""GO:0003849""(3-deoxy-7-phosphoheptulonate synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0009073""(aromatic amino acid family biosynthetic process)|go:""GO:0009423""(chorismate biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_003019186.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:m1lUEdMRczYhn2xGkO99in4GotU177416	intact-crc:4EF8FFB96F954A46|rigid:s5QBNNeQpUJjlaxqIZ81kPCeMKU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UBD5	uniprotkb:Q5NEH1	intact:EBI-374916|uniprotkb:A2A2T5|uniprotkb:Q13565|uniprotkb:Q53GY6|uniprotkb:Q5T159|uniprotkb:Q6IUY7|uniprotkb:Q86TN5|uniprotkb:Q9UG44|uniprotkb:Q9UNT6|uniprotkb:B4E025|ensembl:ENSP00000376586.3	intact:EBI-2796391|uniprotkb:A0A0G2RMG3	psi-mi:orc3_human(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:LATHEO(gene name synonym)|uniprotkb:Origin recognition complex subunit Latheo(gene name synonym)|uniprotkb:ORC3L(gene name synonym)	psi-mi:q5neh1_fratt(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:FTT_1664(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804139|imex:IM-13779-772	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR12748(orthology-group)|refseq:NP_036513.2|refseq:NP_862820.1|refseq:NP_001184188.1|ensembl:ENSG00000135336.17(gene)|ensembl:ENST00000392844.8(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0000808""(origin recognition complex)|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005656""(nuclear pre-replicative complex)|go:""GO:0005664""(nuclear origin of replication recognition complex)|go:""GO:0006260""(DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016604""(nuclear body)|go:""GO:0031261""(DNA replication preinitiation complex)|go:""GO:0061351""(neural precursor cell proliferation)|interpro:IPR020795|interpro:IPR040855|interpro:IPR045663|interpro:IPR045667|mint:Q9UBD5|rcsb pdb:5UJ8|rcsb pdb:5UJM|rcsb pdb:7CTE|rcsb pdb:7CTF|rcsb pdb:7CTG|rcsb pdb:7JPO|rcsb pdb:7JPP|rcsb pdb:7JPQ|rcsb pdb:7JPR|rcsb pdb:7JPS|rcsb pdb:8S0C|rcsb pdb:8S0D|rcsb pdb:8S0E|rcsb pdb:8S0F|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-68616|reactome:R-HSA-68689|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|dip:DIP-31735N"	"go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_170571.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|refseq:WP_003022611.1|interpro:IPR036897|interpro:IPR036914"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ldvEZZ/fRPP3yHQJJIhf0zxYeLM9606	rogid:YUFWDuTGDB9kX/RHTWI6fMTHxU0177416	intact-crc:ADADFD21AA8B236D|rigid:34yFN9o1tJKg+A1a9ZbDIAIqPKE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEU6	uniprotkb:Q13438	intact:EBI-2799541|uniprotkb:A0A0G2RNM1	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|uniprotkb:E7EW91|uniprotkb:G3XA88|ensembl:ENSP00000318165.7	psi-mi:q5neu6_fratt(display_long)|uniprotkb:dnaJ2(gene name)|psi-mi:dnaJ2(display_short)|uniprotkb:FTT_1512c(locus name)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804132|imex:IM-13779-774	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|refseq:YP_170446.1|go:""GO:0005737""(cytoplasm)|go:""GO:0042026""(protein refolding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|refseq:WP_003022390.1|interpro:IPR036869"	"refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|dip:DIP-37493N|ensembl:ENSG00000135506.17(gene)|ensembl:ENST00000315970.12(transcript)|go:""GO:0000836""(Hrd1p ubiquitin ligase complex)|go:""GO:0002020""(protease binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006605""(protein targeting)|go:""GO:0006621""(protein retention in ER lumen)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:1904153""(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|interpro:IPR045149|mint:Q13438|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|panther:PTHR15414(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:vfCNiJP7u4fjKjv/1B6pZtA2dug177416	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	intact-crc:7F3F1DB96CF0BA7D|rigid:89+UDgjAbW5gd3aBFQngEf/91Hc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH99	uniprotkb:Q13438	intact:EBI-2804100|uniprotkb:A0A0G2RQ01	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|uniprotkb:E7EW91|uniprotkb:G3XA88|ensembl:ENSP00000318165.7	psi-mi:q5nh99_fratt(display_long)|uniprotkb:FTT_0568(locus name)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804103|imex:IM-13779-770	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|refseq:YP_169593.1|rcsb pdb:3KD3|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006564""(L-serine biosynthetic process)|go:""GO:0036424""(L-phosphoserine phosphatase activity)|refseq:WP_003023286.1|interpro:IPR036412|interpro:IPR050582"	"refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|dip:DIP-37493N|ensembl:ENSG00000135506.17(gene)|ensembl:ENST00000315970.12(transcript)|go:""GO:0000836""(Hrd1p ubiquitin ligase complex)|go:""GO:0002020""(protease binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006605""(protein targeting)|go:""GO:0006621""(protein retention in ER lumen)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:1904153""(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|interpro:IPR045149|mint:Q13438|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|panther:PTHR15414(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:JbFnfJ9+9d8sJPItg7j1yZOLkXw177416	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	intact-crc:077020B96F9515C8|rigid:v43VfqRezgX6Txco0dU40J1S9m4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13438	uniprotkb:Q5NHS3	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|uniprotkb:E7EW91|uniprotkb:G3XA88|ensembl:ENSP00000318165.7	intact:EBI-2804113	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:q5nhs3_fratt(display_long)|uniprotkb:accD(gene name)|psi-mi:accD(display_short)|uniprotkb:FTT_0372c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804110|imex:IM-13779-773	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|dip:DIP-37493N|ensembl:ENSG00000135506.17(gene)|ensembl:ENST00000315970.12(transcript)|go:""GO:0000836""(Hrd1p ubiquitin ligase complex)|go:""GO:0002020""(protease binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006605""(protein targeting)|go:""GO:0006621""(protein retention in ER lumen)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:1904153""(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|interpro:IPR045149|mint:Q13438|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|panther:PTHR15414(orthology-group)"	"interpro:IPR000438(Acetyl-CoA carboxylase carboxyl transferase, beta subunit)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|refseq:YP_169419.1|go:""GO:0003989""(acetyl-CoA carboxylase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009329""(acetate CoA-transferase complex)|go:""GO:0016743""(carboxyl- or carbamoyltransferase activity)|go:""GO:2001295""(malonyl-CoA biosynthetic process)|interpro:IPR029045|interpro:IPR034733|interpro:IPR041010"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:2Owmz9SIgKc6vGYvTsNRnLQOm8w177416	intact-crc:005A20B96DDE712A|rigid:XsM/NDSppvnxBtw1hi7R1wdrUAs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UBD5	uniprotkb:Q5NET3	intact:EBI-374916|uniprotkb:A2A2T5|uniprotkb:Q13565|uniprotkb:Q53GY6|uniprotkb:Q5T159|uniprotkb:Q6IUY7|uniprotkb:Q86TN5|uniprotkb:Q9UG44|uniprotkb:Q9UNT6|uniprotkb:B4E025|ensembl:ENSP00000376586.3	intact:EBI-2801773	psi-mi:orc3_human(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:LATHEO(gene name synonym)|uniprotkb:Origin recognition complex subunit Latheo(gene name synonym)|uniprotkb:ORC3L(gene name synonym)	psi-mi:q5net3_fratt(display_long)|uniprotkb:fadE(gene name)|psi-mi:fadE(display_short)|uniprotkb:FTT_1529(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804146|imex:IM-13779-776	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR12748(orthology-group)|refseq:NP_036513.2|refseq:NP_862820.1|refseq:NP_001184188.1|ensembl:ENSG00000135336.17(gene)|ensembl:ENST00000392844.8(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0000808""(origin recognition complex)|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005656""(nuclear pre-replicative complex)|go:""GO:0005664""(nuclear origin of replication recognition complex)|go:""GO:0006260""(DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016604""(nuclear body)|go:""GO:0031261""(DNA replication preinitiation complex)|go:""GO:0061351""(neural precursor cell proliferation)|interpro:IPR020795|interpro:IPR040855|interpro:IPR045663|interpro:IPR045667|mint:Q9UBD5|rcsb pdb:5UJ8|rcsb pdb:5UJM|rcsb pdb:7CTE|rcsb pdb:7CTF|rcsb pdb:7CTG|rcsb pdb:7JPO|rcsb pdb:7JPP|rcsb pdb:7JPQ|rcsb pdb:7JPR|rcsb pdb:7JPS|rcsb pdb:8S0C|rcsb pdb:8S0D|rcsb pdb:8S0E|rcsb pdb:8S0F|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-68616|reactome:R-HSA-68689|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|dip:DIP-31735N"	"interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR015396(Protein of unknown function DUF1974)|refseq:YP_170459.3|go:""GO:0004466""(long-chain fatty acyl-CoA dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0033539""(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070991""(medium-chain fatty acyl-CoA dehydrogenase activity)|interpro:IPR036250|interpro:IPR037069|interpro:IPR050741|interpro:IPR046373"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ldvEZZ/fRPP3yHQJJIhf0zxYeLM9606	rogid:kKeqoKaBPWvIJmVTDMU1BWCVmTc177416	intact-crc:D6F1FD21AA34866E|rigid:PR9uypTnvd3/rDQ3nKMrK5RygaI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NG28	uniprotkb:Q6UX06	intact:EBI-2802768|uniprotkb:A0A0G2RPI9	intact:EBI-2804156|uniprotkb:Q5VWG0|uniprotkb:Q86T22|uniprotkb:O95362|ensembl:ENSP00000219022.2	psi-mi:q5ng28_fratt(display_long)|uniprotkb:dacD(gene name)|psi-mi:dacD(display_short)|uniprotkb:FTT_1029(locus name)	psi-mi:olfm4_human(display_long)|uniprotkb:GW112(gene name synonym)|uniprotkb:Antiapoptotic protein GW112(gene name synonym)|uniprotkb:G-CSF-stimulated clone 1 protein(gene name synonym)|uniprotkb:hOLfD(gene name synonym)|uniprotkb:UNQ362/PRO698(orf name)|uniprotkb:OLFM4(gene name)|psi-mi:OLFM4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804153|imex:IM-13779-775	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015956(Penicillin-binding protein-associated)|interpro:IPR018044|interpro:IPR012907(Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal)|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:YP_170014.1|refseq:WP_003021136.1|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|rcsb pdb:6OSU|mint:Q5NG28|interpro:IPR037167"	"refseq:NP_006409.3|ensembl:ENSG00000102837.7(gene)|ensembl:ENST00000219022.3(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0045171""(intercellular bridge)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1904724""(tertiary granule lumen)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR050605|mint:Q6UX06|reactome:R-HSA-6798695|dip:DIP-59533N|panther:PTHR23192(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/13	rogid:EYTPcD8JUkej9Gvps0ogQD5aQ1c177416	rogid:XzvFMvkG5jISzQJdClA/8fF0nbw9606	intact-crc:00509BDAAAE91D35|rigid:E3YGmWfZ9cLEsSoxJQkEh664wng	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH37	uniprotkb:Q5VST9	intact:EBI-2796219|uniprotkb:A0A0G2RMX6	intact:EBI-941850|uniprotkb:Q2A664|uniprotkb:Q5T7G8|uniprotkb:Q5T7G9|uniprotkb:Q5VSU2|uniprotkb:Q86YC7|uniprotkb:Q8NHN0|uniprotkb:Q8NHN1|uniprotkb:Q8NHN2|uniprotkb:Q8NHN3|uniprotkb:Q8NHN4|uniprotkb:Q8NHN5|uniprotkb:Q8NHN6|uniprotkb:Q8NHN7|uniprotkb:Q8NHN8|uniprotkb:Q8NHN9|uniprotkb:Q96AA2|uniprotkb:Q9HCD3|uniprotkb:Q9HCL6|uniprotkb:A0A7P0Z489|ensembl:ENSP00000409493.1	psi-mi:q5nh37_fratt(display_long)|uniprotkb:hflC(gene name)|psi-mi:hflC(display_short)|uniprotkb:FTT_0634(locus name)	psi-mi:obscn_human(display_long)|uniprotkb:OBSCN(gene name)|psi-mi:OBSCN(display_short)|uniprotkb:KIAA1639(gene name synonym)|uniprotkb:Obscurin-myosin light chain kinase(gene name synonym)|uniprotkb:Obscurin-RhoGEF(gene name synonym)|uniprotkb:KIAA1556(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804167|imex:IM-13779-777	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR001107(Band 7 protein)|interpro:IPR010200(HflC)|refseq:YP_169655.1|refseq:WP_003018795.1|interpro:IPR036013"	"rcsb pdb:2EDF|rcsb pdb:2EDH|rcsb pdb:2EDL|ensembl:ENSG00000154358.23(gene)|ensembl:ENST00000422127.5(transcript)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0010314""(phosphatidylinositol-5-phosphate binding)|go:""GO:0016604""(nuclear body)|go:""GO:0030016""(myofibril)|go:""GO:0030018""(Z disc)|go:""GO:0030506""(ankyrin binding)|go:""GO:0031430""(M band)|go:""GO:0031432""(titin binding)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036309""(protein localization to M-band)|go:""GO:0042383""(sarcolemma)|go:""GO:0043325""(phosphatidylinositol-3,4-bisphosphate binding)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045214""(sarcomere organization)|go:""GO:0046872""(metal ion binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035526|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|interpro:IPR052385|interpro:IPR055251|mint:Q5VST9|rcsb pdb:1V1C|rcsb pdb:2CR6|rcsb pdb:2DKU|rcsb pdb:2DM7|rcsb pdb:2E7B|rcsb pdb:2EDQ|rcsb pdb:2EDR|rcsb pdb:2EDT|rcsb pdb:2EDW|rcsb pdb:2ENY|rcsb pdb:2EO1|rcsb pdb:2GQH|rcsb pdb:2MWC|rcsb pdb:2N56|rcsb pdb:2YZ8|rcsb pdb:4C4K|rcsb pdb:4RSV|rcsb pdb:4UOW|rcsb pdb:5TZM|rcsb pdb:6MG9|rcsb pdb:7R67|rcsb pdb:7R68|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013406|refseq:NP_001092093.2|refseq:NP_443075.3|dip:DIP-35727N|efo:""Orphanet:99845""|panther:PTHR35971(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:D91nsJMEfSjitv7++sPB1cVKq9M177416	rogid:38hnJJrkmP7bl9fY/TWDPDMwIGk9606	intact-crc:1632D3A2DA7F407E|rigid:Ai68nPkehT+WfMR4p9QD5iph214	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00365	uniprotkb:Q5NEP5	intact:EBI-2804193	intact:EBI-2802256|uniprotkb:A0A0G2RP86	psi-mi:o00365_human(display_long)	psi-mi:q5nep5_fratt(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:FTT_1575c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804200|imex:IM-13779-779	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR004244(Transposase, L1)|interpro:IPR035300|interpro:IPR035301|interpro:IPR042566|interpro:IPR043636	"interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:YP_170497.1|refseq:WP_003022482.1|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006265""(DNA topological change)|go:""GO:0009330""(""DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex"")|go:""GO:0034335""(DNA negative supercoiling activity)|interpro:IPR035516|interpro:IPR050220|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H73ZL90H4nJdHhxqOFoTzBDBekQ9606	rogid:44gSSjy20htbaT6NxBBvXLNb2sw177416	intact-crc:1D3A509816AB7E8A|rigid:u5XQ9QE2AXsxVIV49Z3OWmo4Xsc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95989	uniprotkb:Q5NFY5	intact:EBI-713708|uniprotkb:B2R8N4|ensembl:ENSP00000476119.1	intact:EBI-2799103|uniprotkb:A0A0G2RM96	psi-mi:nudt3_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 3(gene name synonym)|uniprotkb:NUDT3(gene name)|psi-mi:NUDT3(display_short)|uniprotkb:DIPP(gene name synonym)|uniprotkb:DIPP1(gene name synonym)|uniprotkb:Diadenosine hexaphosphate hydrolase(gene name synonym)|uniprotkb:Endopolyphosphatase(gene name synonym)|uniprotkb:m7GpppN-mRNA hydrolase(gene name synonym)|uniprotkb:m7GpppX diphosphatase(gene name synonym)	psi-mi:q5nfy5_fratt(display_long)|uniprotkb:FTT_1078c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804207|imex:IM-13779-782	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006694.1|ensembl:ENSG00000272325.2(gene)|ensembl:ENST00000607016.2(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000298""(endopolyphosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008486""(diphosphoinositol-polyphosphate diphosphatase activity)|go:""GO:0015961""(diadenosine polyphosphate catabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0034431""(""bis(5'-adenosyl)-hexaphosphatase activity"")|go:""GO:0034432""(""bis(5'-adenosyl)-pentaphosphatase activity"")|go:""GO:0052840""(inositol diphosphate tetrakisphosphate diphosphatase activity)|go:""GO:0052842""(inositol diphosphate pentakisphosphate diphosphatase activity)|go:""GO:0052845""(inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity)|go:""GO:0052848""(inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity)|go:""GO:0071543""(diphosphoinositol polyphosphate metabolic process)|go:""GO:0071544""(diphosphoinositol polyphosphate catabolic process)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0110154""(RNA decapping)|go:""GO:0140932""(""5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity"")|go:""GO:0140933""(""5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"")|go:""GO:1901907""(diadenosine pentaphosphate catabolic process)|go:""GO:1901909""(diadenosine hexaphosphate catabolic process)|go:""GO:1901911""(""adenosine 5'-(hexahydrogen pentaphosphate) catabolic process"")|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR047198|mint:O95989|rcsb pdb:2FVV|rcsb pdb:2Q9P|rcsb pdb:6PCK|rcsb pdb:6PCL|rcsb pdb:6WO7|rcsb pdb:6WO8|rcsb pdb:6WO9|rcsb pdb:6WOA|rcsb pdb:6WOB|rcsb pdb:6WOC|rcsb pdb:6WOD|rcsb pdb:6WOE|rcsb pdb:6WOF|rcsb pdb:6WOG|rcsb pdb:6WOH|rcsb pdb:6WOI|rcsb pdb:7TN4|rcsb pdb:8G9C|rcsb pdb:8G9D|rcsb pdb:8T98|rcsb pdb:8T99|rcsb pdb:8TF9|rcsb pdb:8TFA|reactome:R-HSA-1855167|panther:PTHR12629(orthology-group)"	refseq:WP_003021212.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3DKu6lLJM7uQ2EiUi3NzDPEcZ1g9606	rogid:ZCh5UU3BrwGnp/Qxno/CBNEc368177416	intact-crc:A7F5216B54504BC9|rigid:+AnW6bGFddjBo71tSr32GtEW3bg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00365	uniprotkb:Q5NGF2	intact:EBI-2804193	intact:EBI-2799717|uniprotkb:A0A0G2RNQ0	psi-mi:o00365_human(display_long)	psi-mi:q5ngf2_fratt(display_long)|uniprotkb:AIR synthase(gene name synonym)|uniprotkb:AIRS(gene name synonym)|uniprotkb:purM(gene name)|psi-mi:purM(display_short)|uniprotkb:Phosphoribosyl-aminoimidazole synthetase(gene name synonym)|uniprotkb:FTT_0893(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804190|imex:IM-13779-781	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR004244(Transposase, L1)|interpro:IPR035300|interpro:IPR035301|interpro:IPR042566|interpro:IPR043636	"interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR016188(PurM, N-terminal-like)|refseq:YP_169890.1|rcsb pdb:3M84|rcsb pdb:3QTY|go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004641""(phosphoribosylformylglycinamidine cyclo-ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0046084""(adenine biosynthetic process)|refseq:WP_003020889.1|interpro:IPR036676|interpro:IPR036921"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H73ZL90H4nJdHhxqOFoTzBDBekQ9606	rogid:6AdoQMtF3IgdOJHQCUDoPp3t804177416	intact-crc:23B6B298173987A9|rigid:V7XCuZv7uvgy8W3ko+1Hx+GMrOw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94875	uniprotkb:Q5NGV7	intact:EBI-311323|intact:EBI-747334|uniprotkb:B7Z1G5|uniprotkb:C9JKV9|uniprotkb:G3XAI0|intact:EBI-2804177|uniprotkb:A6NEK9|uniprotkb:O60592|uniprotkb:O60593|uniprotkb:Q96EX0|uniprotkb:D3DP62|uniprotkb:D3DP63|intact:EBI-28977791|uniprotkb:B7Z3X6|ensembl:ENSP00000284776.7|uniprotkb:E9PAS5|uniprotkb:E9PAW4|uniprotkb:B3KPQ7|uniprotkb:H7BXR4|uniprotkb:J3KNZ5|intact:EBI-10983198|intact:EBI-10965282	intact:EBI-2796192	psi-mi:srbs2_human(display_long)|uniprotkb:SORBS2(gene name)|psi-mi:SORBS2(display_short)|uniprotkb:ARGBP2(gene name synonym)|uniprotkb:KIAA0777(gene name synonym)|uniprotkb:Arg/Abl-interacting protein 2(gene name synonym)|uniprotkb:Sorbin(gene name synonym)|uniprotkb:Arg-binding protein 2(gene name synonym)	psi-mi:katg_fratt(display_long)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:FTT_0721c(locus name)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804174|imex:IM-13779-778	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001139142.1|refseq:NP_001139144.1|refseq:NP_001139145.1|refseq:NP_066547.1|refseq:NP_001139146.1|ensembl:ENSG00000154556.20(gene)|ensembl:ENST00000284776.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030018""(Z disc)|go:""GO:0030027""(lamellipodium)|go:""GO:0030425""(dendrite)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045202""(synapse)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061049""(cell growth involved in cardiac muscle cell development)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036028|interpro:IPR050384|mint:O94875|rcsb pdb:5VEI|refseq:NP_001139143.1|refseq:NP_001257700.1|refseq:NP_003594.3|refseq:XP_005263369.1|refseq:XP_006714453.1|refseq:XP_016864260.1|dip:DIP-31634N|panther:PTHR14167(orthology-group)"	"refseq:YP_169735.1|interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|refseq:WP_003020536.1|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ficlNf23am8NpwQVRUKXeVUJTsQ9606	rogid:UVLspYdPWJwb7VPBG0xNq1Pp2KQ177416	intact-crc:8E827CC85B1E13B9|rigid:CP8butckFIQJqQo8YKoVFPjz+Fw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35658	uniprotkb:Q5NGV7	intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400.5	intact:EBI-2796192	psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym)	psi-mi:katg_fratt(display_long)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:FTT_0721c(locus name)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804214|imex:IM-13779-780	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:402014""|efo:""Orphanet:99861""|ensembl:ENSG00000126883.19(gene)|ensembl:ENST00000359428.10(transcript)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0046822""(regulation of nucleocytoplasmic transport)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:1990876""(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC|rcsb pdb:3FMO|rcsb pdb:3FMP|rcsb pdb:5DIS|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9705671|refseq:NP_001305253.1|refseq:NP_001305254.1|refseq:NP_005076.3|dip:DIP-38367N|panther:PTHR23193(orthology-group)"	"refseq:YP_169735.1|interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|refseq:WP_003020536.1|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606	rogid:UVLspYdPWJwb7VPBG0xNq1Pp2KQ177416	intact-crc:FEEAD6A02FB1CB2B|rigid:yUqnxs1hFJPkEWJJmzC8pgu7z/Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGA0	uniprotkb:Q96KG9	intact:EBI-2800784|uniprotkb:A0A0G2RQ90	intact:EBI-949287|intact:EBI-28972634|uniprotkb:A6NJF1|uniprotkb:Q96G50|uniprotkb:Q96KG8|uniprotkb:Q96KH1|uniprotkb:Q9HAW5|uniprotkb:Q9HBL3|uniprotkb:Q9NR53|ensembl:ENSP00000270176.5	psi-mi:q5nga0_fratt(display_long)|uniprotkb:rhlE(gene name)|psi-mi:rhlE(display_short)|uniprotkb:FTT_0952(locus name)	psi-mi:scyl1_human(display_long)|uniprotkb:SCY1-like protein 1(gene name synonym)|uniprotkb:Teratoma-associated tyrosine kinase(gene name synonym)|uniprotkb:Telomerase transcriptional element-interacting factor(gene name synonym)|uniprotkb:Telomerase regulation-associated protein(gene name synonym)|uniprotkb:SCYL1(gene name)|psi-mi:SCYL1(display_short)|uniprotkb:Coated vesicle-associated kinase of 90 kDa(gene name synonym)|uniprotkb:CVAK90(gene name synonym)|uniprotkb:GKLP(gene name synonym)|uniprotkb:NTKL(gene name synonym)|uniprotkb:TAPK(gene name synonym)|uniprotkb:TEIF(gene name synonym)|uniprotkb:TRAP(gene name synonym)|uniprotkb:HT019(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804221|imex:IM-13779-783	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|refseq:YP_169942.1|interpro:IPR027417|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0016787""(hydrolase activity)|refseq:WP_003021019.1|interpro:IPR050079"	"efo:""Orphanet:466794""|ensembl:ENSG00000142186.18(gene)|ensembl:ENST00000270176.10(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0006954""(inflammatory response)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0021522""(spinal cord motor neuron differentiation)|go:""GO:0030126""(COPI vesicle coat)|go:""GO:0045296""(cadherin binding)|go:""GO:0048666""(neuron development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR051177|mint:Q96KG9|refseq:NP_001041683.1|refseq:NP_065731.3|refseq:XP_005274177.1|panther:PTHR12984(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IIfGlhg/cfRi88KrQNS1limaOMY177416	rogid:qHL7to7M3sjqepd3yuU1uo4Mhy49606	intact-crc:BCE85D997456ABA5|rigid:HRQopSuluYva6KoOIxUVkkwVp+M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHZ4	uniprotkb:Q92823	intact:EBI-2798091	intact:EBI-296950|uniprotkb:O15051|uniprotkb:O15179|uniprotkb:Q9UHI3|uniprotkb:Q9UHI4|ensembl:ENSP00000368314.3|uniprotkb:A4D0S3|uniprotkb:E9PDA4|uniprotkb:Q14BM2	psi-mi:syv_fratt(display_long)|uniprotkb:valS(gene name)|psi-mi:valS(display_short)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0299(locus name)	psi-mi:nrcam_human(display_long)|uniprotkb:NRCAM(gene name)|psi-mi:NRCAM(display_short)|uniprotkb:KIAA0343(gene name synonym)|uniprotkb:NgCAM-related cell adhesion molecule(gene name synonym)|uniprotkb:Neuronal surface protein Bravo(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804235|imex:IM-13779-784	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004832""(valine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006438""(valyl-tRNA aminoacylation)|refseq:YP_169348.1|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR019499|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR033705|refseq:WP_003021639.1|interpro:IPR037118"	"ensembl:ENSG00000091129.22(gene)|ensembl:ENST00000379028.8(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007409""(axonogenesis)|go:""GO:0007411""(axon guidance)|go:""GO:0007413""(axonal fasciculation)|go:""GO:0007416""(synapse assembly)|go:""GO:0007417""(central nervous system development)|go:""GO:0007420""(brain development)|go:""GO:0008104""(protein localization)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0019227""(neuronal action potential propagation)|go:""GO:0030424""(axon)|go:""GO:0030506""(ankyrin binding)|go:""GO:0030516""(regulation of axon extension)|go:""GO:0031290""(retinal ganglion cell axon guidance)|go:""GO:0043005""(neuron projection)|go:""GO:0043194""(axon initial segment)|go:""GO:0045162""(clustering of voltage-gated sodium channels)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0086080""(protein binding involved in heterotypic cell-cell adhesion)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098632""(cell-cell adhesion mediator activity)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099175""(regulation of postsynapse organization)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR051170|mint:Q92823|rcsb pdb:1UEN|rcsb pdb:1UEY|reactome:R-HSA-445095|reactome:R-HSA-447038|reactome:R-HSA-447043|refseq:NP_001032209.1|refseq:NP_001180511.1|refseq:NP_001180512.1|refseq:NP_001180513.1|refseq:NP_005001.3|refseq:XP_005250430.1|refseq:XP_006716066.1|refseq:XP_016867746.1|efo:""Orphanet:528084""|panther:PTHR44170(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:x/UHW8BtUK4O+DP24Ws5NMlvUpw177416	rogid:5R0by2rhqdhNVUKuigwoClm9gZI9606	intact-crc:D347FC9F3F66B581|rigid:WltbGO91Lrz1AZMe+Q4NSZkFgFs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q02297	uniprotkb:Q5NHP5	intact:EBI-2460704|uniprotkb:B7Z4Z3|uniprotkb:E9PHH4|uniprotkb:A5YAK4|uniprotkb:A5YAK5|uniprotkb:O14667|uniprotkb:P98202|uniprotkb:Q02298|uniprotkb:Q02299|uniprotkb:Q07110|uniprotkb:Q07111|uniprotkb:Q12779|uniprotkb:Q12780|uniprotkb:Q12781|uniprotkb:Q12782|uniprotkb:Q12783|uniprotkb:Q12784|uniprotkb:Q15491|uniprotkb:Q7RTV9|uniprotkb:Q7RTW0|uniprotkb:Q7RTW1|uniprotkb:Q7RTW2|uniprotkb:Q8NFN1|uniprotkb:Q8NFN2|uniprotkb:Q8NFN3|uniprotkb:Q9UPE3|uniprotkb:A8K1L2|ensembl:ENSP00000384620.2	intact:EBI-2797363|uniprotkb:A0A0G2RNY4	psi-mi:nrg1_human(display_long)|uniprotkb:NRG1(gene name)|psi-mi:NRG1(display_short)|uniprotkb:GGF(gene name synonym)|uniprotkb:HGL(gene name synonym)|uniprotkb:HRGA(gene name synonym)|uniprotkb:NDF(gene name synonym)|uniprotkb:SMDF(gene name synonym)	psi-mi:q5nhp5_fratt(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:FTT_0402(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804228|imex:IM-13779-785	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001153467.1|refseq:NP_001153471.1|refseq:NP_001153473.1|refseq:NP_001153477.1|refseq:NP_039250.2|refseq:NP_039251.2|refseq:NP_039252.2|refseq:NP_039253.1|refseq:NP_039256.2|refseq:NP_039258.1|refseq:NP_001309134.1|refseq:NP_001309135.1|refseq:NP_001309136.1|refseq:NP_001153480.1|dip:DIP-355N|ensembl:ENSG00000157168.22(gene)|ensembl:ENST00000405005.8(transcript)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007154""(cell communication)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007171""(activation of transmembrane receptor protein tyrosine kinase activity)|go:""GO:0007399""(nervous system development)|go:""GO:0007420""(brain development)|go:""GO:0007422""(peripheral nervous system development)|go:""GO:0008083""(growth factor activity)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0014032""(neural crest cell development)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030297""(transmembrane receptor protein tyrosine kinase activator activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030879""(mammary gland development)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032148""(activation of protein kinase B activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0038129""(ERBB3 signaling pathway)|go:""GO:0038130""(ERBB4 signaling pathway)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0038135""(ERBB2-ERBB4 signaling pathway)|go:""GO:0038138""(ERBB4-ERBB4 signaling pathway)|go:""GO:0042060""(wound healing)|go:""GO:0043125""(ErbB-3 class receptor binding)|go:""GO:0045499""(chemorepellent activity)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0051048""(negative regulation of secretion)|go:""GO:0051155""(positive regulation of striated muscle cell differentiation)|go:""GO:0051238""(obsolete sequestering of metal ion)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0055012""(ventricular cardiac muscle cell differentiation)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060956""(endocardial cell differentiation)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1900086""(positive regulation of peptidyl-tyrosine autophosphorylation)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002154(Neuregulin 1-related, C-terminal)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018250|interpro:IPR036179|interpro:IPR040180|mint:Q02297|rcsb pdb:1HAE|rcsb pdb:1HAF|rcsb pdb:1HRE|rcsb pdb:1HRF|rcsb pdb:3U7U|rcsb pdb:7MN5|rcsb pdb:7MN6|rcsb pdb:7MN8|rcsb pdb:7SJL|rcsb pdb:8U4I|rcsb pdb:8U4L|reactome:R-HSA-1227986|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1250342|reactome:R-HSA-1250347|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-1306955|reactome:R-HSA-1358803|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8863795|reactome:R-HSA-9620244|reactome:R-HSA-9664565|reactome:R-HSA-9665686|refseq:NP_039254.1|panther:PTHR11100(orthology-group)"	"go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0006260""(DNA replication)|go:""GO:0008408""(3'-5' exonuclease activity)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR004805(DNA polymerase III, alpha subunit)|refseq:YP_169447.1|interpro:IPR029460|refseq:WP_003020102.1|interpro:IPR040982|interpro:IPR041931"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:J2CMur3i1USt6QII/qpk4+FmY1o9606	rogid:DwkzHVE9BAI7dWosyyMu+MR6dHw177416	intact-crc:704C4E46FB481443|rigid:de7Za4Z9RzE7IgJMk/LwDybOKvw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFK7	uniprotkb:P06748	intact:EBI-2797846|uniprotkb:A0A0G2RN70	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:q5nfk7_fratt(display_long)|uniprotkb:rne(gene name)|psi-mi:rne(display_short)|uniprotkb:FTT_1227(locus name)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804253|imex:IM-13779-786	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006364""(rRNA processing)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008033""(tRNA processing)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008995""(ribonuclease E activity)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019843""(rRNA binding)|interpro:IPR028878|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR019307|interpro:IPR004659(Ribonuclease E and G)|refseq:YP_170185.1|refseq:WP_003021514.1|interpro:IPR048583"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:T1YeruV0gQXSr2JVi+sAPAQCsl0177416	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:A6DCF6EBABDA4E3D|rigid:nWHGk57oVA6wjQpg3Vrlq8s+Mic	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH91	uniprotkb:P06748	intact:EBI-2804245|uniprotkb:A0A0G2RMJ8	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:q5nh91_fratt(display_long)|uniprotkb:sdaA(gene name)|psi-mi:sdaA(display_short)|uniprotkb:FTT_0577(locus name)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804242|imex:IM-13779-787	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004644(Iron-sulphur-dependent L-serine dehydratase single chain form)|interpro:IPR005130(Serine dehydratase alpha chain)|interpro:IPR005131(Serine dehydratase beta chain)|refseq:YP_169601.1|go:""GO:0003941""(L-serine ammonia-lyase activity)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR029009|refseq:WP_003019268.1|interpro:IPR051318"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rAJJN6zltZpSciqSe5iWZMw1tLg177416	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:254A58EBAA0207D0|rigid:uStvybW8OzeDEqVyUkQBlNWrplI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z494	uniprotkb:Q5NEW4	intact:EBI-2804263|uniprotkb:Q68D99|uniprotkb:Q8NCM5|uniprotkb:Q7Z493|uniprotkb:Q5JPE3|uniprotkb:Q96NK2|uniprotkb:Q5JPE6|uniprotkb:Q6NVH3|uniprotkb:Q96N70|uniprotkb:Q7Z492|uniprotkb:Q8N9R2|ensembl:ENSP00000338766.5	intact:EBI-2804278|uniprotkb:A0A0G2RNG0	psi-mi:nphp3_human(display_long)|uniprotkb:KIAA2000(gene name synonym)|uniprotkb:NPHP3(gene name)|psi-mi:NPHP3(display_short)	psi-mi:q5new4_fratt(display_long)|uniprotkb:FTT_1493c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804260|imex:IM-13779-788	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000113971.21(gene)|ensembl:ENST00000337331.10(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001947""(heart looping)|go:""GO:0003283""(atrial septum development)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030324""(lung development)|go:""GO:0035469""(determination of pancreatic left/right asymmetry)|go:""GO:0045494""(photoreceptor cell maintenance)|go:""GO:0048496""(maintenance of animal organ identity)|go:""GO:0060026""(convergent extension)|go:""GO:0060027""(convergent extension involved in gastrulation)|go:""GO:0060271""(cilium assembly)|go:""GO:0060287""(epithelial cilium movement involved in determination of left/right asymmetry)|go:""GO:0060993""(kidney morphogenesis)|go:""GO:0071908""(determination of intestine left/right asymmetry)|go:""GO:0071909""(determination of stomach left/right asymmetry)|go:""GO:0071910""(determination of liver left/right asymmetry)|go:""GO:0072189""(ureter development)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097543""(ciliary inversin compartment)|go:""GO:0097546""(ciliary base)|go:""GO:1905515""(non-motile cilium assembly)|go:""GO:2000095""(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|mint:Q7Z494|rcsb pdb:5L7K|reactome:R-HSA-5624138|refseq:NP_694972.3|efo:""Orphanet:294415""|efo:""Orphanet:3032""|efo:""Orphanet:3156""|efo:""Orphanet:93589""|efo:""Orphanet:93591""|panther:PTHR45641(orthology-group)"	refseq:YP_170428.1|refseq:WP_003022358.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7SitCJ9bwhu4VXh9FjX/wWCq0UQ9606	rogid:27huGXtUR7EE86YZGD/S43e1SDg177416	intact-crc:E23D38CD2B83B3A7|rigid:ScVxd0baKUMkYdQzaDEmQ8MIOdg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NII2	uniprotkb:P55209	intact:EBI-2804321|uniprotkb:A0A0G2RQ93	intact:EBI-356392|uniprotkb:B3KNT8|ensembl:ENSP00000376947.3|ensembl:ENSP00000477538.1|uniprotkb:B3KV44|intact:EBI-21355522	psi-mi:q5nii2_fratt(display_long)|uniprotkb:FTT_0086(locus name)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804318|imex:IM-13779-793	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR006314(Dyp-type peroxidase)|refseq:YP_169160.1|go:""GO:0004601""(peroxidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0046872""(metal ion binding)|refseq:WP_003019812.1|interpro:IPR048328"	"refseq:NP_004528.1|refseq:NP_631946.1|ensembl:ENSG00000187109.15(gene)|ensembl:ENST00000393263.7(transcript)|ensembl:ENST00000618691.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0042393""(histone binding)|go:""GO:0042470""(melanosome)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0140713""(histone chaperone activity)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|interpro:IPR002164(""Nucleosome assembly protein (NAP)"")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|rcsb pdb:7UN3|rcsb pdb:7UN6|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|panther:PTHR11875(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+LH1WQceEflVrrfjPoxm4EmXWgc177416	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	intact-crc:3B4EFE898A466A8F|rigid:8ghLFjbwPHc1j/ctgRhiccovgb4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NE85	uniprotkb:Q8IVI9	intact:EBI-2804331|uniprotkb:A0A0G2RP69	intact:EBI-1391643|uniprotkb:Q27HG3|uniprotkb:Q53S62|uniprotkb:Q96CJ9|uniprotkb:A8K2I9|uniprotkb:B3KSF5|uniprotkb:E7EPT9|ensembl:ENSP00000318921.7	psi-mi:q5ne85_fratt(display_long)|uniprotkb:FTT_1766(locus name)	psi-mi:nostn_human(display_long)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Nitric oxide synthase traffic inducer(gene name synonym)|uniprotkb:BM247 homolog(gene name synonym)|uniprotkb:NOSTRIN(gene name)|psi-mi:NOSTRIN(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804328|imex:IM-13779-791	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002935(O-methyltransferase, family 3)|refseq:YP_170657.1|go:""GO:0008171""(O-methyltransferase activity)|go:""GO:0008757""(S-adenosylmethionine-dependent methyltransferase activity)|go:""GO:0032259""(methylation)|interpro:IPR029063|refseq:WP_003022768.1|interpro:IPR050362"	"refseq:NP_001034813.2|refseq:NP_001165102.1|refseq:NP_001165103.1|refseq:NP_443178.2|panther:PTHR14167(orthology-group)|ensembl:ENSG00000163072.16(gene)|ensembl:ENST00000317647.12(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0007165""(signal transduction)|go:""GO:0016477""(cell migration)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|interpro:IPR036274|mint:Q8IVI9|rcsb pdb:2YUN|reactome:R-HSA-203641"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DsKY2FA8Z0z1XBn+A7aPkBNF/B4177416	rogid:995orjHO0YRgvNcLMP1kX2qC25s9606	intact-crc:61E33D4C8E43BF5A|rigid:u+NgPOrLlpY4q3OnoWbZjjk7Ia8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH18	uniprotkb:P55209	intact:EBI-2803823	intact:EBI-356392|uniprotkb:B3KNT8|ensembl:ENSP00000376947.3|ensembl:ENSP00000477538.1|uniprotkb:B3KV44|intact:EBI-21355522	psi-mi:ruvc_fratt(display_long)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:FTT_0656(locus name)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804311|imex:IM-13779-790	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR020563|refseq:WP_003026245.1|refseq:YP_169674.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0008821""(crossover junction DNA endonuclease activity)|go:""GO:0048476""(Holliday junction resolvase complex)|interpro:IPR036397"	"refseq:NP_004528.1|refseq:NP_631946.1|ensembl:ENSG00000187109.15(gene)|ensembl:ENST00000393263.7(transcript)|ensembl:ENST00000618691.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0042393""(histone binding)|go:""GO:0042470""(melanosome)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0140713""(histone chaperone activity)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|interpro:IPR002164(""Nucleosome assembly protein (NAP)"")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|rcsb pdb:7UN3|rcsb pdb:7UN6|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|panther:PTHR11875(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:p3PMc7Cb2k7iNiw3z/2YJKvwcmE177416	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	intact-crc:F14B8F8988087838|rigid:EcarsICMuRBlRxOYunYaI7GxOXY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NQX5	uniprotkb:Q5NIP6	intact:EBI-748927|uniprotkb:Q5SPY8|uniprotkb:Q9BTD6|uniprotkb:Q9BXT3|uniprotkb:Q9NQS2|uniprotkb:Q9Y434|ensembl:ENSP00000360660.4	intact:EBI-2796567	psi-mi:npdc1_human(display_long)|uniprotkb:NPDC1(gene name)|psi-mi:NPDC1(display_short)	psi-mi:gata_fratt(display_long)|uniprotkb:FTT_0020(locus name)|uniprotkb:gatA(gene name)|psi-mi:gatA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804285|imex:IM-13779-789	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056207.3|ensembl:ENSG00000107281.10(gene)|ensembl:ENST00000371601.5(transcript)|go:""GO:0005886""(plasma membrane)|interpro:IPR009635(Neural proliferation differentiation control-1)|reactome:R-HSA-198933|panther:PTHR23352(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0030956""(""glutamyl-tRNA(Gln) amidotransferase complex"")|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|interpro:IPR000120(Amidase signature enzyme)|interpro:IPR020556|interpro:IPR023631|interpro:IPR004412(""Glutamyl-tRNA(Gln) amidotransferase A subunit"")|refseq:YP_169096.1|refseq:WP_003022862.1|interpro:IPR036928"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XMT47N4ONSRPydRJyvdcqEyTs3Q9606	rogid:PXaa59Zvn1xzo0G3HrDFgI8WSJg177416	intact-crc:FA1CFA0445275680|rigid:Qz/Nx7LWEyunBL/jK/4WkUFJMdI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q49A26	uniprotkb:Q5NGE6	intact:EBI-2804292|uniprotkb:Q6P1Q2|uniprotkb:C9JJ40|uniprotkb:Q9BTI1|uniprotkb:Q9BXK2|uniprotkb:Q6V3W7|uniprotkb:C9JJ60|uniprotkb:B4DL47|uniprotkb:Q5U632|ensembl:ENSP00000322716.6	intact:EBI-2796264|uniprotkb:A0A0G2RNI3	psi-mi:glyr1_human(display_long)|uniprotkb:HIBDL(gene name synonym)|uniprotkb:NP60(gene name synonym)|uniprotkb:3-hydroxyisobutyrate dehydrogenase-like protein(gene name synonym)|uniprotkb:Glyoxylate reductase 1 homolog(gene name synonym)|uniprotkb:Nuclear protein NP60(gene name synonym)|uniprotkb:Nuclear protein of 60 kDa(gene name synonym)|uniprotkb:GLYR1(gene name)|psi-mi:GLYR1(display_short)|uniprotkb:NPAC(gene name synonym)|uniprotkb:Putative oxidoreductase GLYR1(gene name synonym)|uniprotkb:NDF(gene name synonym)|uniprotkb:Nucleosome-destabilizing factor(gene name synonym)	psi-mi:q5nge6_fratt(display_long)|uniprotkb:prlC(gene name)|psi-mi:prlC(display_short)|uniprotkb:FTT_0899c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804304|imex:IM-13779-792	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011521019.1|refseq:NP_115958.2|ensembl:ENSG00000140632.17(gene)|ensembl:ENST00000321919.14(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000786""(nucleosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0031491""(nucleosome binding)|go:""GO:0035064""(methylated histone binding)|go:""GO:0042393""(histone binding)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|go:""GO:0140463""(chromatin-protein adaptor activity)|go:""GO:0140673""(transcription elongation-coupled chromatin remodeling)|interpro:IPR000313(PWWP)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR029154|interpro:IPR035501|interpro:IPR036291|interpro:IPR051265|mint:Q49A26|rcsb pdb:2UYY|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GUT|rcsb pdb:4GUU|rcsb pdb:4HSU|rcsb pdb:6R1U|rcsb pdb:6R25|refseq:NP_001295025.1|refseq:NP_001311026.1|panther:PTHR43580(orthology-group)"	"go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|refseq:YP_169896.1|interpro:IPR024079|refseq:WP_003020904.1|interpro:IPR024077|interpro:IPR045090|interpro:IPR045666|interpro:IPR034005"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QsJhkB7Klk8D2R03vqPZzbi3f9g9606	rogid:iZq1PA9Cyrdilxgx1L5ibpr8DmY177416	intact-crc:B8FB47C9207A9643|rigid:0N2MCuQwPb484q/PJeMuMEATZBY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P29474	uniprotkb:Q5NG92	intact:EBI-1391623|uniprotkb:A0S0A7|uniprotkb:E9PFR2|uniprotkb:Q13662|uniprotkb:Q14251|uniprotkb:Q14434|uniprotkb:Q6GSL5|uniprotkb:A8KA63|uniprotkb:B2RCQ1|uniprotkb:Q548C1|uniprotkb:Q9UDC6|uniprotkb:A0S0A8|ensembl:ENSP00000297494.3	intact:EBI-2804345|uniprotkb:A0A0G2RMW6	psi-mi:nos3_human(display_long)|uniprotkb:EC-NOS(gene name synonym)|uniprotkb:NOS type III(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NOS3(gene name)|psi-mi:NOS3(display_short)|uniprotkb:Nitric oxide synthase, endothelial(gene name synonym)	psi-mi:q5ng92_fratt(display_long)|uniprotkb:FTT_0960(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804348|imex:IM-13779-794	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000594.2|refseq:NP_001153581.1|refseq:NP_001153582.1|refseq:NP_001153583.1|refseq:XP_016867721.1|dip:DIP-38479N|panther:PTHR19384(orthology-group)|ensembl:ENSG00000164867.11(gene)|ensembl:ENST00000297494.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001525""(angiogenesis)|go:""GO:0001542""(ovulation from ovarian follicle)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0003057""(regulation of the force of heart contraction by chemical signal)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003785""(actin monomer binding)|go:""GO:0004517""(nitric-oxide synthase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0006527""(arginine catabolic process)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0006813""(potassium ion transport)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007263""(nitric oxide mediated signal transduction)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009408""(response to heat)|go:""GO:0009725""(response to hormone)|go:""GO:0010181""(FMN binding)|go:""GO:0010544""(negative regulation of platelet activation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014740""(negative regulation of muscle hyperplasia)|go:""GO:0014806""(smooth muscle hyperplasia)|go:""GO:0019430""(removal of superoxide radicals)|go:""GO:0020037""(heme binding)|go:""GO:0030324""(lung development)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031284""(positive regulation of guanylate cyclase activity)|go:""GO:0031644""(regulation of nervous system process)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0034405""(response to fluid shear stress)|go:""GO:0034617""(tetrahydrobiopterin binding)|go:""GO:0034618""(arginine binding)|go:""GO:0042311""(vasodilation)|go:""GO:0043267""(negative regulation of potassium ion transport)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045776""(negative regulation of blood pressure)|go:""GO:0046870""(cadmium ion binding)|go:""GO:0048662""(negative regulation of smooth muscle cell proliferation)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0050661""(NADP binding)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051926""(negative regulation of calcium ion transport)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097746""(blood vessel diameter maintenance)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|interpro:IPR044940|interpro:IPR044943|interpro:IPR044944|interpro:IPR050607|mint:P29474|rcsb pdb:1M9J|rcsb pdb:1M9K|rcsb pdb:1M9M|rcsb pdb:1M9Q|rcsb pdb:1M9R|rcsb pdb:1NIW|rcsb pdb:2LL7|rcsb pdb:2MG5|rcsb pdb:2N8J|rcsb pdb:3EAH|rcsb pdb:3NOS|rcsb pdb:4D1O|rcsb pdb:4D1P|rcsb pdb:5UO8|rcsb pdb:5UO9|rcsb pdb:5UOA|rcsb pdb:5UOB|rcsb pdb:5UOC|rcsb pdb:5VVB|rcsb pdb:5VVC|rcsb pdb:5VVD|rcsb pdb:5XOF|rcsb pdb:6AV6|rcsb pdb:6AV7|rcsb pdb:6CIE|rcsb pdb:6CIF|rcsb pdb:6NH1|rcsb pdb:6NH2|rcsb pdb:6NH3|rcsb pdb:6NH4|rcsb pdb:6NH5|rcsb pdb:6NH6|rcsb pdb:6NH7|rcsb pdb:6NH8|rcsb pdb:6NHF|rcsb pdb:6POU|rcsb pdb:6POV|rcsb pdb:6POW|rcsb pdb:6POX|rcsb pdb:6POY|rcsb pdb:6POZ|rcsb pdb:6PP0|rcsb pdb:6PP1|rcsb pdb:6PP2|rcsb pdb:6PP3|rcsb pdb:6PP4|rcsb pdb:7M56|rcsb pdb:7TSG|rcsb pdb:7TSH|rcsb pdb:7TSI|rcsb pdb:7TSK|rcsb pdb:7TSL|rcsb pdb:7TSM|rcsb pdb:7TSN|rcsb pdb:7TSO|rcsb pdb:7TSP|rcsb pdb:7UAO|rcsb pdb:8FGN|rcsb pdb:8FGO|rcsb pdb:8FGP|rcsb pdb:8FGQ|rcsb pdb:8FGR|rcsb pdb:8FGS|rcsb pdb:8FGT|rcsb pdb:8FGU|rcsb pdb:8UFR|rcsb pdb:8UFS|rcsb pdb:8UFT|rcsb pdb:8UFU|reactome:R-HSA-1222556|reactome:R-HSA-1474151|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-203754|reactome:R-HSA-392154|reactome:R-HSA-5218920|reactome:R-HSA-9009391|reactome:R-HSA-9856530|ensembl:ENSP00000297494.3|ensembl:ENST00000467517.1|ensembl:ENSP00000420551.1|ensembl:ENST00000484524.5|ensembl:ENSP00000420215.1"	"interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|refseq:YP_169950.1|go:""GO:0016788""(hydrolase activity, acting on ester bonds)|go:""GO:0046872""(metal ion binding)|refseq:WP_003021033.1|interpro:IPR053138"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:FIvVY2y5ltfs8KVWaMEHCEt2pMk9606	rogid:XZfDSo1tXvOODvsQ3pPW6VSA+8E177416	intact-crc:F9E0014E4D02FCC3|rigid:zqTO6tXN9WcuazBMmf+aOSQOkZg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV7	uniprotkb:P29474	intact:EBI-2796192	intact:EBI-1391623|uniprotkb:A0S0A7|uniprotkb:E9PFR2|uniprotkb:Q13662|uniprotkb:Q14251|uniprotkb:Q14434|uniprotkb:Q6GSL5|uniprotkb:A8KA63|uniprotkb:B2RCQ1|uniprotkb:Q548C1|uniprotkb:Q9UDC6|uniprotkb:A0S0A8|ensembl:ENSP00000297494.3	psi-mi:katg_fratt(display_long)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:FTT_0721c(locus name)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)	psi-mi:nos3_human(display_long)|uniprotkb:EC-NOS(gene name synonym)|uniprotkb:NOS type III(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NOS3(gene name)|psi-mi:NOS3(display_short)|uniprotkb:Nitric oxide synthase, endothelial(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804338|imex:IM-13779-797	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169735.1|interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|refseq:WP_003020536.1|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)"	"refseq:NP_000594.2|refseq:NP_001153581.1|refseq:NP_001153582.1|refseq:NP_001153583.1|refseq:XP_016867721.1|dip:DIP-38479N|panther:PTHR19384(orthology-group)|ensembl:ENSG00000164867.11(gene)|ensembl:ENST00000297494.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001525""(angiogenesis)|go:""GO:0001542""(ovulation from ovarian follicle)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0003057""(regulation of the force of heart contraction by chemical signal)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003785""(actin monomer binding)|go:""GO:0004517""(nitric-oxide synthase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0006527""(arginine catabolic process)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0006813""(potassium ion transport)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007263""(nitric oxide mediated signal transduction)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009408""(response to heat)|go:""GO:0009725""(response to hormone)|go:""GO:0010181""(FMN binding)|go:""GO:0010544""(negative regulation of platelet activation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014740""(negative regulation of muscle hyperplasia)|go:""GO:0014806""(smooth muscle hyperplasia)|go:""GO:0019430""(removal of superoxide radicals)|go:""GO:0020037""(heme binding)|go:""GO:0030324""(lung development)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031284""(positive regulation of guanylate cyclase activity)|go:""GO:0031644""(regulation of nervous system process)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0034405""(response to fluid shear stress)|go:""GO:0034617""(tetrahydrobiopterin binding)|go:""GO:0034618""(arginine binding)|go:""GO:0042311""(vasodilation)|go:""GO:0043267""(negative regulation of potassium ion transport)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045776""(negative regulation of blood pressure)|go:""GO:0046870""(cadmium ion binding)|go:""GO:0048662""(negative regulation of smooth muscle cell proliferation)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0050661""(NADP binding)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051926""(negative regulation of calcium ion transport)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097746""(blood vessel diameter maintenance)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|interpro:IPR044940|interpro:IPR044943|interpro:IPR044944|interpro:IPR050607|mint:P29474|rcsb pdb:1M9J|rcsb pdb:1M9K|rcsb pdb:1M9M|rcsb pdb:1M9Q|rcsb pdb:1M9R|rcsb pdb:1NIW|rcsb pdb:2LL7|rcsb pdb:2MG5|rcsb pdb:2N8J|rcsb pdb:3EAH|rcsb pdb:3NOS|rcsb pdb:4D1O|rcsb pdb:4D1P|rcsb pdb:5UO8|rcsb pdb:5UO9|rcsb pdb:5UOA|rcsb pdb:5UOB|rcsb pdb:5UOC|rcsb pdb:5VVB|rcsb pdb:5VVC|rcsb pdb:5VVD|rcsb pdb:5XOF|rcsb pdb:6AV6|rcsb pdb:6AV7|rcsb pdb:6CIE|rcsb pdb:6CIF|rcsb pdb:6NH1|rcsb pdb:6NH2|rcsb pdb:6NH3|rcsb pdb:6NH4|rcsb pdb:6NH5|rcsb pdb:6NH6|rcsb pdb:6NH7|rcsb pdb:6NH8|rcsb pdb:6NHF|rcsb pdb:6POU|rcsb pdb:6POV|rcsb pdb:6POW|rcsb pdb:6POX|rcsb pdb:6POY|rcsb pdb:6POZ|rcsb pdb:6PP0|rcsb pdb:6PP1|rcsb pdb:6PP2|rcsb pdb:6PP3|rcsb pdb:6PP4|rcsb pdb:7M56|rcsb pdb:7TSG|rcsb pdb:7TSH|rcsb pdb:7TSI|rcsb pdb:7TSK|rcsb pdb:7TSL|rcsb pdb:7TSM|rcsb pdb:7TSN|rcsb pdb:7TSO|rcsb pdb:7TSP|rcsb pdb:7UAO|rcsb pdb:8FGN|rcsb pdb:8FGO|rcsb pdb:8FGP|rcsb pdb:8FGQ|rcsb pdb:8FGR|rcsb pdb:8FGS|rcsb pdb:8FGT|rcsb pdb:8FGU|rcsb pdb:8UFR|rcsb pdb:8UFS|rcsb pdb:8UFT|rcsb pdb:8UFU|reactome:R-HSA-1222556|reactome:R-HSA-1474151|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-203754|reactome:R-HSA-392154|reactome:R-HSA-5218920|reactome:R-HSA-9009391|reactome:R-HSA-9856530|ensembl:ENSP00000297494.3|ensembl:ENST00000467517.1|ensembl:ENSP00000420551.1|ensembl:ENST00000484524.5|ensembl:ENSP00000420215.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:UVLspYdPWJwb7VPBG0xNq1Pp2KQ177416	rogid:FIvVY2y5ltfs8KVWaMEHCEt2pMk9606	intact-crc:997F014E4C39B086|rigid:ViqyHymF2WTH9b65tdVfJP6uspY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHP5	uniprotkb:Q76FK4	intact:EBI-2797363|uniprotkb:A0A0G2RNY4	intact:EBI-396069|uniprotkb:Q5TCC7|uniprotkb:Q5TCC8|uniprotkb:Q5TCD3|uniprotkb:Q5TCD5|uniprotkb:Q5TCD6|uniprotkb:Q5TCD7|uniprotkb:Q76D35|uniprotkb:Q7L3E2|uniprotkb:Q9H586|uniprotkb:Q9H795|uniprotkb:Q9H7W7|uniprotkb:Q9H9J6|uniprotkb:Q9NWA4|uniprotkb:Q9NWM4|ensembl:ENSP00000401177.2|ensembl:ENSP00000441140.1|ensembl:ENSP00000516776.1|ensembl:ENSP00000516780.1	psi-mi:q5nhp5_fratt(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:FTT_0402(locus name)	psi-mi:nol8_human(display_long)|uniprotkb:Nucleolar protein Nop132(gene name synonym)|uniprotkb:NOL8(gene name)|psi-mi:NOL8(display_short)|uniprotkb:C9orf34(gene name synonym)|uniprotkb:NOP132(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804355|imex:IM-13779-798	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0006260""(DNA replication)|go:""GO:0008408""(3'-5' exonuclease activity)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR004805(DNA polymerase III, alpha subunit)|refseq:YP_169447.1|interpro:IPR029460|refseq:WP_003020102.1|interpro:IPR040982|interpro:IPR041931"	"refseq:NP_060418.4|refseq:NP_001243323.1|refseq:XP_006717229.1|refseq:XP_006717230.1|refseq:XP_006717232.1|refseq:XP_006717233.1|ensembl:ENSG00000198000.12(gene)|ensembl:ENSG00000291347.1(gene)|ensembl:ENST00000442668.7(transcript)|ensembl:ENST00000545558.5(transcript)|ensembl:ENST00000707203.1(transcript)|ensembl:ENST00000707208.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0006364""(rRNA processing)|go:""GO:1902570""(protein localization to nucleolus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034138|interpro:IPR035979|mint:Q76FK4|refseq:XP_011517126.1|refseq:NP_001317651.1|refseq:XP_016870365.1|panther:PTHR48029(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DwkzHVE9BAI7dWosyyMu+MR6dHw177416	rogid:tKGGHXKwb9YuzARkLi19za57xZM9606	intact-crc:4B07A3384189D25A|rigid:HYm0EY2gxYUmC/lLcYR2i+JrSvk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHX0	uniprotkb:Q6KC79	intact:EBI-2799263	intact:EBI-722767|uniprotkb:Q6KCD6|uniprotkb:Q6N080|uniprotkb:Q6ZT92|uniprotkb:Q7Z2E6|uniprotkb:Q8N4M5|uniprotkb:Q9Y6Y3|uniprotkb:Q9Y6Y4|ensembl:ENSP00000282516.8	psi-mi:efg_fratt(display_long)|uniprotkb:FTT_0323(locus name)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)	psi-mi:nipbl_human(display_long)|uniprotkb:Delangin(gene name synonym)|uniprotkb:SCC2 homolog(gene name synonym)|uniprotkb:NIPBL(gene name)|psi-mi:NIPBL(display_short)|uniprotkb:IDN3(gene name synonym)|uniprotkb:SCC2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804362|imex:IM-13779-795	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169372.1|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR031157|refseq:WP_003028885.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|interpro:IPR047872"	"ensembl:ENSG00000164190.19(gene)|ensembl:ENST00000282516.13(transcript)|go:""GO:0000070""(mitotic sister chromatid segregation)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001656""(metanephros development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006974""(DNA damage response)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0007420""(brain development)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008104""(protein localization)|go:""GO:0032039""(integrator complex)|go:""GO:0032116""(SMC loading complex)|go:""GO:0034087""(establishment of mitotic sister chromatid cohesion)|go:""GO:0034088""(maintenance of mitotic sister chromatid cohesion)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0035115""(embryonic forelimb morphogenesis)|go:""GO:0035136""(forelimb morphogenesis)|go:""GO:0035261""(external genitalia morphogenesis)|go:""GO:0036033""(mediator complex binding)|go:""GO:0040018""(positive regulation of multicellular organism growth)|go:""GO:0042471""(ear morphogenesis)|go:""GO:0042634""(regulation of hair cycle)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045778""(positive regulation of ossification)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048557""(embryonic digestive tract morphogenesis)|go:""GO:0048565""(digestive tract development)|go:""GO:0048589""(developmental growth)|go:""GO:0048592""(eye morphogenesis)|go:""GO:0048638""(regulation of developmental growth)|go:""GO:0048703""(embryonic viscerocranium morphogenesis)|go:""GO:0050890""(cognition)|go:""GO:0060325""(face morphogenesis)|go:""GO:0061010""(gallbladder development)|go:""GO:0061038""(uterus morphogenesis)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0061780""(obsolete mitotic cohesin loading)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070087""(chromo shadow domain binding)|go:""GO:0071169""(establishment of protein localization to chromatin)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0090694""(Scc2-Scc4 cohesin loading complex)|go:""GO:1990414""(replication-born double-strand break repair via sister chromatid exchange)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2001224""(positive regulation of neuron migration)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024986|interpro:IPR026003|interpro:IPR033031|mint:Q6KC79|rcsb pdb:6WG3|rcsb pdb:6WGE|rcsb pdb:7W1M|reactome:R-HSA-2470946|refseq:NP_056199.2|refseq:NP_597677.2|refseq:XP_016864819.1|efo:""Orphanet:199""|efo:""Orphanet:329802""|dip:DIP-29199N|panther:PTHR21704(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:hULyXsLqQVOFqECbDOTlNV2kzrY177416	rogid:RaZLQ4CmlJD/3QUl7n1JKBT23GM9606	intact-crc:76FC275D6152F3B1|rigid:XtK78OAm59OnwNbKXHj8SUfsZN4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NPE2	uniprotkb:Q5NG24	intact:EBI-2683432|uniprotkb:Q4V9L7|uniprotkb:Q9HBL4|uniprotkb:B2R6M8|ensembl:ENSP00000368389.4	intact:EBI-2803358|uniprotkb:A0A0G2RMN6	psi-mi:ngrn_human(display_long)|uniprotkb:FI58G(gene name synonym)|uniprotkb:Mesenchymal stem cell protein DSC92(gene name synonym)|uniprotkb:Neurite outgrowth-associated protein(gene name synonym)|uniprotkb:Spinal cord-derived protein FI58G(gene name synonym)|uniprotkb:HT020(orf name)|uniprotkb:NGRN(gene name)|psi-mi:NGRN(display_short)	psi-mi:q5ng24_fratt(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:FTT_1035c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804369|imex:IM-13779-796	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001028260.2|ensembl:ENSG00000182768.9(gene)|ensembl:ENST00000379095.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0016604""(nuclear body)|go:""GO:0019843""(rRNA binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0045171""(intercellular bridge)|go:""GO:0061668""(mitochondrial ribosome assembly)|go:""GO:0070131""(positive regulation of mitochondrial translation)|go:""GO:0072686""(mitotic spindle)|interpro:IPR010487(Neugrin)|mint:Q9NPE2|panther:PTHR13475(orthology-group)"	"interpro:IPR028630|interpro:IPR007627(RNA polymerase sigma-70 region 2)|refseq:YP_170018.1|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016987""(sigma factor activity)|refseq:WP_003021146.1|interpro:IPR042189|interpro:IPR036388|interpro:IPR050239"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:B0tJk1JglYD2jh37lUDOKV0qEBg9606	rogid:8d3IsZ3gHsN+yZIi+h+WLgKX8Tc177416	intact-crc:7A00C507052CB960|rigid:IpgORlehdbPcTuAQ74aYASFiwy0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q5NIG1	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2799910|uniprotkb:A0A0G2RM79	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q5nig1_fratt(display_long)|uniprotkb:polA(gene name)|psi-mi:polA(display_short)|uniprotkb:FTT_0111(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804383|imex:IM-13779-801	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"refseq:YP_169181.1|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR020046|interpro:IPR020045|interpro:IPR002421(5'-3' exonuclease)|interpro:IPR019760|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR018320|interpro:IPR002298(DNA polymerase A)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006302""(double-strand break repair)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0008409""(5'-3' exonuclease activity)|interpro:IPR029060|refseq:WP_003019852.1|interpro:IPR036279|interpro:IPR036397|interpro:IPR043502"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:i8oe3SbGM1jV9pBfqQP0T5cI+MQ177416	intact-crc:59F8C1CC45585D07|rigid:8Yi6ZFrDkwWTNkPtzzbSUtmF7ZU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q5NH38	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2797227|uniprotkb:A0A0G2RP54	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q5nh38_fratt(display_long)|uniprotkb:hflK(gene name)|psi-mi:hflK(display_short)|uniprotkb:FTT_0633(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804390|imex:IM-13779-800	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"go:""GO:0016020""(membrane)|interpro:IPR001107(Band 7 protein)|interpro:IPR010201(HflK)|refseq:YP_169654.1|refseq:WP_003023444.1|interpro:IPR036013|interpro:IPR050710"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:0bj8rSZ7SoJuK6iGQz/clayaUPs177416	intact-crc:6EB1B0CC47F0DA3D|rigid:KnzixkB8piD6afMXXj9b7wIuzf4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q5NGB2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2804397	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:biob_fratt(display_long)|uniprotkb:FTT_0937c(locus name)|uniprotkb:bioB(gene name)|psi-mi:bioB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804401|imex:IM-13779-802	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR010722(Biotin and thiamin synthesis associated)|interpro:IPR002684(Biotin synthase)|interpro:IPR024177|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|refseq:YP_169930.1|go:""GO:0004076""(biotin synthase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0009102""(biotin biosynthetic process)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_003020978.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:39ilTCuZxkaXf3uPU2xun5jhIKs177416	intact-crc:C6696FCC45BC70A3|rigid:A0/jzqiwStuvc0C+q5ZCODRcJ/o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFP9	uniprotkb:Q13952	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	intact:EBI-389755|uniprotkb:F8VWM3|uniprotkb:Q59GY4|uniprotkb:Q5T6K8|uniprotkb:Q5T6L1|uniprotkb:Q5TZR6|uniprotkb:Q92869|uniprotkb:Q9HBX1|uniprotkb:Q9NXB5|uniprotkb:Q9UM67|uniprotkb:Q9UML0|uniprotkb:Q9UMT7|uniprotkb:D3DPV9|uniprotkb:B4DUS6|uniprotkb:B4DW63|uniprotkb:Q5T6K9|ensembl:ENSP00000312617.5	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	psi-mi:nfyc_human(display_long)|uniprotkb:NFYC(gene name)|psi-mi:NFYC(display_short)|uniprotkb:Nuclear transcription factor Y subunit C(gene name synonym)|uniprotkb:CAAT box DNA-binding protein subunit C(gene name synonym)|uniprotkb:Transactivator HSM-1/2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804376|imex:IM-13779-799	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	"refseq:NP_001295043.1|refseq:NP_001295044.1|refseq:XP_011539818.1|refseq:NP_001136059.1|refseq:NP_001136060.1|refseq:NP_001136061.1|refseq:NP_001136062.1|refseq:NP_055038.2|refseq:XP_005270951.1|refseq:XP_006710724.1|refseq:XP_005270952.3|refseq:XP_006710721.2|refseq:XP_006710723.2|refseq:XP_006710725.2|ensembl:ENSG00000066136.21(gene)|ensembl:ENST00000308733.9(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006457""(protein folding)|go:""GO:0016602""(CCAAT-binding factor complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR050568|mint:Q13952|rcsb pdb:1N1J|rcsb pdb:4AWL|rcsb pdb:4CSR|rcsb pdb:6QMP|rcsb pdb:6QMQ|rcsb pdb:6QMS|rcsb pdb:7AH8|rcsb pdb:8QU2|rcsb pdb:8QU3|rcsb pdb:8QU4|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|refseq:XP_016856857.1|refseq:XP_016856858.1|refseq:XP_016856854.1|refseq:XP_016856856.1|panther:PTHR10252(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	rogid:q87lGBkQG8fQbzcSDNlcGX7lmXc9606	intact-crc:C131F888D1A95D43|rigid:VYv9P6dy/Av7UDphpxRz+1FWiCs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI89	uniprotkb:Q14494	intact:EBI-2796250	intact:EBI-2804436|uniprotkb:Q96FN6|uniprotkb:Q12877|uniprotkb:D3DTU3|uniprotkb:D3DTU5|ensembl:ENSP00000354855.3|intact:EBI-28976146	psi-mi:q5ni89_fratt(display_long)|uniprotkb:lysS(gene name synonym)|uniprotkb:lysU(gene name)|psi-mi:lysU(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0192(locus name)	psi-mi:nf2l1_human(display_long)|uniprotkb:HBZ17(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:TCF11(gene name synonym)|uniprotkb:Locus control region-factor 1(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 1(gene name synonym)|uniprotkb:Transcription factor 11(gene name synonym)|uniprotkb:NFE2L1(gene name)|psi-mi:NFE2L1(display_short)|uniprotkb:Nuclear factor erythroid 2-related factor 1(gene name synonym)|uniprotkb:Protein NRF1, p120 form(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804433|imex:IM-13779-807	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|interpro:IPR044136|refseq:YP_169253.1|interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR045864"	"refseq:NP_003195.1|refseq:XP_005257467.1|refseq:XP_005257469.1|ensembl:ENSG00000082641.16(gene)|ensembl:ENST00000362042.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008289""(lipid binding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0042802""(identical protein binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR047167|mint:Q14494|refseq:NP_001317191.1|panther:PTHR24411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4e6LdrlEB4PMi+b0yLmkVagonC4177416	rogid:/mXRFWPHxGFlrQmbhG3eDz9uXoc9606	intact-crc:2D4BEC8360117F49|rigid:Cxs9TJH0Ijesnabdd0NxPaP5T44	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFG5	uniprotkb:P19838	intact:EBI-2800139	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q5nfg5_fratt(display_long)|uniprotkb:mltA(gene name)|psi-mi:mltA(display_short)|uniprotkb:Murein hydrolase A(gene name synonym)|uniprotkb:FTT_1271(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804408|imex:IM-13779-803	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010611(3D)|interpro:IPR005300(MltA)|refseq:YP_170227.1|interpro:IPR026044|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0008933""(peptidoglycan lytic transglycosylase activity)|go:""GO:0009253""(peptidoglycan catabolic process)|go:""GO:0009254""(peptidoglycan turnover)|go:""GO:0019867""(outer membrane)|go:""GO:0071555""(cell wall organization)|interpro:IPR036908"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:0xim/ygDKez8ngsvlYghUNDjlOE177416	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:E9011ECC442BA393|rigid:Wb9CRpR1I78qfEygRDzt/oOj+NU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH42	uniprotkb:P19838	intact:EBI-2804422	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	"psi-mi:miaa_fratt(display_long)|uniprotkb:""Dimethylallyl diphosphate:tRNA dimethylallyltransferase""(gene name synonym)|uniprotkb:""Isopentenyl-diphosphate:tRNA isopentenyltransferase""(gene name synonym)|uniprotkb:FTT_0629(locus name)|uniprotkb:miaA(gene name)|psi-mi:miaA(display_short)"	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804426|imex:IM-13779-804	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039657|interpro:IPR018022|refseq:YP_169650.1|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006400""(tRNA modification)|go:""GO:0052381""(tRNA dimethylallyltransferase activity)|refseq:WP_003015652.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:WK61ETXkZkAnJoc3JvcVvcmOJjc177416	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:66E6B0CC45AF49F8|rigid:kFAjNu1G/sF0MIy5ljqSQO8FtUY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14494	uniprotkb:Q5NF50	intact:EBI-2804436|uniprotkb:Q96FN6|uniprotkb:Q12877|uniprotkb:D3DTU3|uniprotkb:D3DTU5|ensembl:ENSP00000354855.3|intact:EBI-28976146	intact:EBI-2799423|uniprotkb:A0A0G2RN72	psi-mi:nf2l1_human(display_long)|uniprotkb:HBZ17(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:TCF11(gene name synonym)|uniprotkb:Locus control region-factor 1(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 1(gene name synonym)|uniprotkb:Transcription factor 11(gene name synonym)|uniprotkb:NFE2L1(gene name)|psi-mi:NFE2L1(display_short)|uniprotkb:Nuclear factor erythroid 2-related factor 1(gene name synonym)|uniprotkb:Protein NRF1, p120 form(gene name synonym)	psi-mi:q5nf50_fratt(display_long)|uniprotkb:Exonuclease V subunit RecC(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecC(gene name synonym)|uniprotkb:recC(gene name)|psi-mi:recC(display_short)|uniprotkb:FTT_1397c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804446|imex:IM-13779-805	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003195.1|refseq:XP_005257467.1|refseq:XP_005257469.1|ensembl:ENSG00000082641.16(gene)|ensembl:ENST00000362042.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008289""(lipid binding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0042802""(identical protein binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR047167|mint:Q14494|refseq:NP_001317191.1|panther:PTHR24411(orthology-group)"	"interpro:IPR006697(Exodeoxyribonuclease V, RecC subunit)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|refseq:YP_170342.1|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|refseq:WP_003022201.1|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR041500"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/mXRFWPHxGFlrQmbhG3eDz9uXoc9606	rogid:dix8s5jOlPbCloD4EjJhnk5rYr4177416	intact-crc:C38F338362A9B073|rigid:SusxZ7Od7ttfd1WD7wbUj8Kea/o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q5NEC0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804415|imex:IM-13779-806	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:98A28DCC4505D217|rigid:kicCObA7fwWt5IxywrXBhHfLPAg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96SB3	uniprotkb:Q5NGR8	intact:EBI-351275|uniprotkb:Q8TCR9|intact:EBI-28984643|ensembl:ENSP00000478767.1|intact:EBI-4401886|uniprotkb:D3DTX6	intact:EBI-2804477|uniprotkb:A0A0G2RNZ4	psi-mi:neb2_human(display_long)|uniprotkb:Neurabin-II(gene name synonym)|uniprotkb:Spinophilin(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)|uniprotkb:PPP1R9B(gene name)|psi-mi:PPP1R9B(display_short)|uniprotkb:PPP1R6(gene name synonym)	psi-mi:q5ngr8_fratt(display_long)|uniprotkb:glyS(gene name)|psi-mi:glyS(display_short)|uniprotkb:Glycyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:FTT_0764(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804474|imex:IM-13779-809	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108819.11(gene)|ensembl:ENST00000612501.2(transcript)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0001560""(regulation of cell growth by extracellular stimulus)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003006""(developmental process involved in reproduction)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007015""(actin filament organization)|go:""GO:0007096""(regulation of exit from mitosis)|go:""GO:0007612""(learning)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0008380""(RNA splicing)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016358""(dendrite development)|go:""GO:0016477""(cell migration)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019900""(kinase binding)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030175""(filopodium)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031175""(neuron projection development)|go:""GO:0031749""(D2 dopamine receptor binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0035094""(response to nicotine)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044326""(dendritic spine neck)|go:""GO:0044327""(dendritic spine head)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051015""(actin filament binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060179""(male mating behavior)|go:""GO:0061458""(reproductive system development)|go:""GO:0071315""(cellular response to morphine)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0097444""(spine apparatus)|refseq:NP_115984.3|go:""GO:0098890""(extrinsic component of postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1901653""(cellular response to peptide)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903119""(protein localization to actin cytoskeleton)|go:""GO:1904372""(positive regulation of protein localization to actin cortical patch)|go:""GO:1904373""(response to kainic acid)|go:""GO:1904386""(response to L-phenylalanine derivative)|go:""GO:1990778""(protein localization to cell periphery)|go:""GO:1990780""(cytoplasmic side of dendritic spine plasma membrane)|go:""GO:2000474""(regulation of opioid receptor signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:Q96SB3|panther:PTHR16154(orthology-group)"	"interpro:IPR008909(DALR anticodon binding)|interpro:IPR006194(Glycyl-tRNA synthetase, class II, heterodimeric)|interpro:IPR015944(Glycyl-tRNA synthetase, class IIc, beta subunit)|refseq:YP_169774.1|go:""GO:0004814""(arginine-tRNA ligase activity)|go:""GO:0004820""(glycine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006420""(arginyl-tRNA aminoacylation)|go:""GO:0006426""(glycyl-tRNA aminoacylation)|refseq:WP_003020626.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:X6fQLpaYhXCqzRlQNEoX67P/HbU9606	rogid:/WGBKDHNu5yRvWij90pXYwDMp0w177416	intact-crc:0A95FCEC34E12448|rigid:cM4IzPAUjZkb4/dCFGBhzPflJ50	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF74	uniprotkb:Q99519	intact:EBI-2796785|uniprotkb:A0A0G2RND4	intact:EBI-721517|ensembl:ENSP00000229725.4|ensembl:ENSP00000364782.4|ensembl:ENSP00000399309.3|ensembl:ENSP00000401067.2|ensembl:ENSP00000403720.2|ensembl:ENSP00000408207.2|ensembl:ENSP00000408957.2|ensembl:ENSP00000409489.2	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	psi-mi:neur1_human(display_long)|uniprotkb:Lysosomal sialidase(gene name synonym)|uniprotkb:N-acetyl-alpha-neuraminidase 1(gene name synonym)|uniprotkb:Acetylneuraminyl hydrolase(gene name synonym)|uniprotkb:G9 sialidase(gene name synonym)|uniprotkb:NEU1(gene name)|psi-mi:NEU1(display_short)|uniprotkb:NANH(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804453|imex:IM-13779-810	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"efo:""Orphanet:812""|efo:""Orphanet:93399""|efo:""Orphanet:93400""|ensembl:ENSG00000184494.8(gene)|ensembl:ENSG00000204386.13(gene)|ensembl:ENSG00000223957.6(gene)|ensembl:ENSG00000227129.6(gene)|ensembl:ENSG00000227315.7(gene)|ensembl:ENSG00000228691.6(gene)|ensembl:ENSG00000234343.6(gene)|ensembl:ENSG00000234846.7(gene)|ensembl:ENST00000229725.4(transcript)|ensembl:ENST00000375631.5(transcript)|ensembl:ENST00000411774.3(transcript)|ensembl:ENST00000422978.2(transcript)|ensembl:ENST00000423382.2(transcript)|ensembl:ENST00000434496.2(transcript)|ensembl:ENST00000437432.2(transcript)|ensembl:ENST00000439648.2(transcript)|go:""GO:0004308""(exo-alpha-sialidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006689""(ganglioside catabolic process)|go:""GO:0009313""(oligosaccharide catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016997""(alpha-sialidase activity)|go:""GO:0030054""(cell junction)|go:""GO:0035580""(specific granule lumen)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR011040(Neuraminidase)|interpro:IPR026856|interpro:IPR036278|mint:Q99519|reactome:R-HSA-4085001|reactome:R-HSA-4341670|reactome:R-HSA-6798695|reactome:R-HSA-9840310|refseq:NP_000425.1|panther:PTHR10628(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	rogid:ZVyKW74LB/iEd+Ys7Lm7ZyLvv609606	intact-crc:3FCB5E2B57767898|rigid:LMenTwGPgsePlNYFfHxr5WtNwec	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HB63	uniprotkb:Q5NFA1	intact:EBI-743459|uniprotkb:Q658K9|uniprotkb:Q7L3F1|uniprotkb:Q7L9D6|uniprotkb:Q7Z5B6|uniprotkb:Q9BZP1|uniprotkb:Q9NT44|uniprotkb:Q9P133|uniprotkb:B2RNC2|ensembl:ENSP00000340998.4	intact:EBI-2797066|uniprotkb:A0A0G2RM98	psi-mi:net4_human(display_long)|uniprotkb:Beta-netrin(gene name synonym)|uniprotkb:Hepar-derived netrin-like protein(gene name synonym)|uniprotkb:NTN4(gene name)|psi-mi:NTN4(display_short)	psi-mi:q5nfa1_fratt(display_long)|uniprotkb:FTT_1339c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804467|imex:IM-13779-811	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067052.2|refseq:NP_001316629.1|refseq:NP_001316630.1|refseq:NP_001316631.1|dip:DIP-46274N|ensembl:ENSG00000074527.13(gene)|ensembl:ENST00000343702.9(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009888""(tissue development)|go:""GO:0016322""(neuron remodeling)|go:""GO:0016477""(cell migration)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0043237""(laminin-1 binding)|go:""GO:0043256""(laminin complex)|go:""GO:0060668""(regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling)|go:""GO:0070831""(basement membrane assembly)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|interpro:IPR035811|interpro:IPR050440|mint:Q9HB63|reactome:R-HSA-3000171|reactome:R-HSA-373752|panther:PTHR10574(orthology-group)|ensembl:ENSP00000340998.4|ensembl:ENST00000344911.8|ensembl:ENSP00000339436.4|ensembl:ENST00000538383.5|ensembl:ENSP00000444432.1|ensembl:ENST00000553059.1|ensembl:ENSP00000447292.1"	"go:""GO:0016020""(membrane)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|refseq:YP_170291.1|interpro:IPR036513|interpro:IPR052706|refseq:WP_003022095.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:Wiq3R27SFsSneLrCDSpL19glpxE9606	rogid:6Zt8IB73d/bI77NTYHhVCWhbQ0U177416	intact-crc:6BFF03A2DDB0B73B|rigid:ZJD0diyxYcSKYXGpymnWqrWwAK8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFN4	uniprotkb:Q9HB63	intact:EBI-2796796	intact:EBI-743459|uniprotkb:Q658K9|uniprotkb:Q7L3F1|uniprotkb:Q7L9D6|uniprotkb:Q7Z5B6|uniprotkb:Q9BZP1|uniprotkb:Q9NT44|uniprotkb:Q9P133|uniprotkb:B2RNC2|ensembl:ENSP00000340998.4	psi-mi:uvrb_fratt(display_long)|uniprotkb:Excinuclease ABC subunit B(gene name synonym)|uniprotkb:FTT_1199c(locus name)|uniprotkb:uvrB(gene name)|psi-mi:uvrB(display_short)	psi-mi:net4_human(display_long)|uniprotkb:Beta-netrin(gene name synonym)|uniprotkb:Hepar-derived netrin-like protein(gene name synonym)|uniprotkb:NTN4(gene name)|psi-mi:NTN4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804460|imex:IM-13779-808	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170158.1|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004807(Excinuclease ABC, B subunit)|interpro:IPR024759|interpro:IPR027417|interpro:IPR036876|interpro:IPR041471|refseq:WP_003021449.1"	"refseq:NP_067052.2|refseq:NP_001316629.1|refseq:NP_001316630.1|refseq:NP_001316631.1|dip:DIP-46274N|ensembl:ENSG00000074527.13(gene)|ensembl:ENST00000343702.9(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009888""(tissue development)|go:""GO:0016322""(neuron remodeling)|go:""GO:0016477""(cell migration)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0043237""(laminin-1 binding)|go:""GO:0043256""(laminin complex)|go:""GO:0060668""(regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling)|go:""GO:0070831""(basement membrane assembly)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|interpro:IPR035811|interpro:IPR050440|mint:Q9HB63|reactome:R-HSA-3000171|reactome:R-HSA-373752|panther:PTHR10574(orthology-group)|ensembl:ENSP00000340998.4|ensembl:ENST00000344911.8|ensembl:ENSP00000339436.4|ensembl:ENST00000538383.5|ensembl:ENSP00000444432.1|ensembl:ENST00000553059.1|ensembl:ENSP00000447292.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:Jhq9KYkHYrpyhq5qkOrHkcqCWVk177416	rogid:Wiq3R27SFsSneLrCDSpL19glpxE9606	intact-crc:772003A2DC9CC4A0|rigid:9JBNTKAdMCBJjGeKBSPk+oDpHi4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHH0	uniprotkb:O60502	intact:EBI-2801640|uniprotkb:A0A0G2RN01	intact:EBI-715814|uniprotkb:O75166|uniprotkb:Q86WV0|uniprotkb:Q8IV98|uniprotkb:Q9BVA5|uniprotkb:Q9HAR0|uniprotkb:B7WPB9|uniprotkb:D3DR79|uniprotkb:E9PGF9|ensembl:ENSP00000354850.3	psi-mi:q5nhh0_fratt(display_long)|uniprotkb:FTT_0484(locus name)	psi-mi:oga_human(display_long)|uniprotkb:OGA(gene name)|psi-mi:OGA(display_short)|uniprotkb:Beta-N-acetylglucosaminidase(gene name synonym)|uniprotkb:Beta-N-acetylhexosaminidase(gene name synonym)|uniprotkb:Beta-hexosaminidase(gene name synonym)|uniprotkb:HEXC(gene name synonym)|uniprotkb:KIAA0679(gene name synonym)|uniprotkb:MEA5(gene name synonym)|uniprotkb:MGEA5(gene name synonym)|uniprotkb:Meningioma-expressed antigen 5(gene name synonym)|uniprotkb:N-acetyl-beta-D-glucosaminidase(gene name synonym)|uniprotkb:N-acetyl-beta-glucosaminidase(gene name synonym)|uniprotkb:Nuclear cytoplasmic O-GlcNAcase and acetyltransferase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804492|imex:IM-13779-812	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_169522.1|refseq:WP_003020297.1	"refseq:NP_001135906.1|refseq:NP_036347.1|ensembl:ENSG00000198408.14(gene)|ensembl:ENST00000361464.8(transcript)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006044""(N-acetylglucosamine metabolic process)|go:""GO:0006493""(protein O-linked glycosylation)|go:""GO:0006516""(glycoprotein catabolic process)|go:""GO:0006517""(protein deglycosylation)|go:""GO:0009100""(glycoprotein metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016231""(beta-N-acetylglucosaminidase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0102571""(""[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity"")|interpro:IPR011496(Hyaluronidase eukaryotic/prokaryotic)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR051822|mint:O60502|rcsb pdb:2YDQ|rcsb pdb:5M7R|rcsb pdb:5M7S|rcsb pdb:5M7T|rcsb pdb:5M7U|rcsb pdb:5TKE|rcsb pdb:5UHK|rcsb pdb:5UHL|rcsb pdb:5UHO|rcsb pdb:5UHP|rcsb pdb:5UN8|rcsb pdb:5UN9|rcsb pdb:5VVO|rcsb pdb:5VVT|rcsb pdb:5VVU|rcsb pdb:5VVV|rcsb pdb:5VVX|rcsb pdb:6HKI|rcsb pdb:6PM9|rcsb pdb:7OU6|rcsb pdb:7YEH|rcsb pdb:8P0L|panther:PTHR13170(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:85+752TOqMA9Cs7A1Xauk1I1owE177416	rogid:KEvP6+2BWwsxrs8hsIjQhKAQGVo9606	intact-crc:5962BBA133EAB16B|rigid:gJmIeHc08TNWiZqZ2j6GE+yMsv4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCG8	uniprotkb:Q5NI89	intact:EBI-373289|uniprotkb:Q05DC2|uniprotkb:Q4G135|uniprotkb:Q52LF0|uniprotkb:Q6PEX2|uniprotkb:Q7Z6I0|uniprotkb:Q9H5L3|uniprotkb:Q9H6Q6|intact:EBI-2561242|ensembl:ENSP00000387006.3	intact:EBI-2796250	psi-mi:cwc22_human(display_long)|uniprotkb:CWC22(gene name)|psi-mi:CWC22(display_short)|uniprotkb:fSAPb(gene name synonym)|uniprotkb:KIAA1604(gene name synonym)|uniprotkb:NCM(gene name synonym)|uniprotkb:Nucampholin homolog(gene name synonym)	psi-mi:q5ni89_fratt(display_long)|uniprotkb:lysS(gene name synonym)|uniprotkb:lysU(gene name)|psi-mi:lysU(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0192(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804506|imex:IM-13779-813	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_065994.1|refseq:XP_005246783.1|ensembl:ENSG00000163510.14(gene)|ensembl:ENST00000410053.8(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0016607""(nuclear speck)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071006""(U2-type catalytic step 1 spliceosome)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR050781|mint:Q9HCG8|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7DVQ|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:9FMD|reactome:R-HSA-72163|dip:DIP-31268N|panther:PTHR18034(orthology-group)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|interpro:IPR044136|refseq:YP_169253.1|interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/21	rogid:LQcs0QFEY4f8ha4jLuOAyz/N5ic9606	rogid:4e6LdrlEB4PMi+b0yLmkVagonC4177416	intact-crc:74703E318160B795|rigid:z1Omcxcatl1G67ulLLJHJZai6ag	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75376	uniprotkb:Q5NID1	intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|uniprotkb:B3DLF8|ensembl:ENSP00000268712.2	intact:EBI-2796238	psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym)	psi-mi:rpoc_fratt(display_long)|uniprotkb:RNA polymerase subunit beta'(gene name synonym)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:FTT_0145(locus name)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804485|imex:IM-13779-814	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-29402N|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1|refseq:XP_011522388.1|panther:PTHR13992(orthology-group)|ensembl:ENSG00000141027.23(gene)|ensembl:ENST00000268712.8(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0016020""(membrane)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045820""(negative regulation of glycolytic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045922""(negative regulation of fatty acid metabolic process)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0072686""(mitotic spindle)|go:""GO:1902894""(negative regulation of miRNA transcription)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|interpro:IPR051571|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3H52|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6WMS|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|rcsb pdb:8AS9|rcsb pdb:8D8I|rcsb pdb:8DKN|rcsb pdb:8DKV|rcsb pdb:8FHE|rcsb pdb:8FHG|rcsb pdb:8FKC|rcsb pdb:8FKD|rcsb pdb:8FKE|rcsb pdb:8FKF|rcsb pdb:8FKG|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|ensembl:ENSP00000268712.2|ensembl:ENST00000395848.5|ensembl:ENSP00000379189.1|ensembl:ENST00000395851.5|ensembl:ENSP00000379192.1"	"go:""GO:0000287""(magnesium ion binding)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0008270""(zinc ion binding)|interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|refseq:YP_169211.1|refseq:WP_003019910.1|interpro:IPR038120|interpro:IPR044893|interpro:IPR045867|interpro:IPR042102"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606	rogid:nCrO43u1Xg+RCZk3AEfSW6oQCNA177416	intact-crc:68B0C661850487D2|rigid:5e9w+Gkl9fT3hKhJGBrlHr/OulM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGI2	uniprotkb:Q9Y6Q9	intact:EBI-2799802	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066.3|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	psi-mi:rnph_fratt(display_long)|uniprotkb:tRNA nucleotidyltransferase(gene name synonym)|uniprotkb:FTT_0858(locus name)|uniprotkb:rph(gene name)|psi-mi:rph(display_short)	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804499|imex:IM-13779-815	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR002381(Ribonuclease phosphorolytic, bacterial-type)|interpro:IPR018336|refseq:YP_169860.1|interpro:IPR027408|go:""GO:0000049""(tRNA binding)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0006364""(rRNA processing)|go:""GO:0008033""(tRNA processing)|go:""GO:0009022""(tRNA nucleotidyltransferase activity)|go:""GO:0016075""(rRNA catabolic process)|refseq:WP_003020838.1|interpro:IPR036345|interpro:IPR050080"	"refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151.19(gene)|ensembl:ENST00000371998.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035624""(receptor transactivation)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043697""(cell dedifferentiation)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070561""(vitamin D receptor signaling pathway)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|dip:DIP-30876N|ensembl:ENST00000371997.3|ensembl:ENSP00000361065.3|ensembl:ENSP00000361066.3|ensembl:ENST00000372004.7|ensembl:ENSP00000361073.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/12	rogid:u3qShCbTaGy16VuExtjWVWb/iOg177416	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	intact-crc:A79FACB562F94BA4|rigid:vNg1PMPoLAo8ddX9juDRvBJmxmM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15080	uniprotkb:Q5NIP6	intact:EBI-1036870|uniprotkb:O60808|uniprotkb:Q86U56|uniprotkb:Q9BU98|uniprotkb:Q9NP45|ensembl:ENSP00000248899.6|uniprotkb:A8K4F9|intact:EBI-28974814	intact:EBI-2796567	psi-mi:ncf4_human(display_long)|uniprotkb:NCF4(gene name)|psi-mi:NCF4(display_short)|uniprotkb:Neutrophil NADPH oxidase factor 4(gene name synonym)|uniprotkb:p40-phox(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 4(gene name synonym)|uniprotkb:SH3PXD4(gene name synonym)	psi-mi:gata_fratt(display_long)|uniprotkb:FTT_0020(locus name)|uniprotkb:gatA(gene name)|psi-mi:gatA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804513|imex:IM-13779-817	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100365.16(gene)|ensembl:ENST00000248899.11(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006909""(phagocytosis)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016176""(superoxide-generating NADPH oxidase activator activity)|go:""GO:0032010""(phagolysosome)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0042554""(superoxide anion generation)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0045730""(respiratory burst)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000919(Neutrophil cytosol factor P40)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR034853|interpro:IPR034912|interpro:IPR035541|interpro:IPR036028|interpro:IPR036871|interpro:IPR051228|interpro:IPR053793|mint:Q15080|rcsb pdb:1H6H|rcsb pdb:1OEY|rcsb pdb:1W6X|rcsb pdb:1W70|rcsb pdb:1Z9Q|rcsb pdb:2DYB|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|refseq:NP_000622.2|refseq:NP_038202.2|efo:""Orphanet:379""|dip:DIP-17019N|panther:PTHR15706(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0030956""(""glutamyl-tRNA(Gln) amidotransferase complex"")|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|interpro:IPR000120(Amidase signature enzyme)|interpro:IPR020556|interpro:IPR023631|interpro:IPR004412(""Glutamyl-tRNA(Gln) amidotransferase A subunit"")|refseq:YP_169096.1|refseq:WP_003022862.1|interpro:IPR036928"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gQ1MnSPLdf7S4yHbXzXKGskLtBE9606	rogid:PXaa59Zvn1xzo0G3HrDFgI8WSJg177416	intact-crc:C3028D4CA08B7172|rigid:1jPaZwMpvzp/LUXl6Xpw7q/EzFU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIC1	uniprotkb:Q3BBV0	intact:EBI-2804527	intact:EBI-2804530|uniprotkb:Q9C0H0|uniprotkb:Q8N4E8|uniprotkb:S4R3K2	"psi-mi:q5nic1_fratt(display_long)|uniprotkb:""2-oxoglutarate dioxygenase (ethylene-forming)""(gene name synonym)|uniprotkb:""2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)""(gene name synonym)|uniprotkb:FTT_0155(locus name)"	psi-mi:nbpf1_human(display_long)|uniprotkb:KIAA1693(gene name synonym)|uniprotkb:NBPF1(gene name)|psi-mi:NBPF1(display_short)|uniprotkb:Neuroblastoma breakpoint family member 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804537|imex:IM-13779-818	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005123(""2OG-Fe(II) oxygenase"")|refseq:YP_169221.1|interpro:IPR027443|go:""GO:0009693""(ethylene biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0102276""(""2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity"")|interpro:IPR044861|interpro:IPR050231"	"refseq:NP_060410.2|interpro:IPR010630(Protein of unknown function DUF1220)|go:""GO:0005737""(cytoplasm)|interpro:IPR055306|mint:Q3BBV0|ensembl:ENST00000430580.6|ensembl:ENSP00000474456.1|ensembl:ENSG00000219481.11|panther:PTHR14199(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mb27RpkykDKLgMt+uLglqsE7890177416	rogid:df9dRNH9FlktRbcB4eZJiICNysA9606	intact-crc:88C0781D9CF331CD|rigid:9YTwxHDy7uokSlWZg5ek20dl/rM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19878	uniprotkb:Q5NF74	intact:EBI-489611|ensembl:ENSP00000356505.4|ensembl:ENSP00000356506.1|ensembl:ENSP00000513258.1|uniprotkb:Q2PP06|uniprotkb:Q8NFC7|uniprotkb:Q9BV51|uniprotkb:B2R6Q1|uniprotkb:B4DKQ7|uniprotkb:B4DQA7|uniprotkb:E9PHJ2|uniprotkb:E9PHX3	intact:EBI-2796785|uniprotkb:A0A0G2RND4	psi-mi:ncf2_human(display_long)|uniprotkb:NOXA2(gene name synonym)|uniprotkb:P67PHOX(gene name synonym)|uniprotkb:Neutrophil NADPH oxidase factor 2(gene name synonym)|uniprotkb:NADPH oxidase activator 2(gene name synonym)|uniprotkb:67 kDa neutrophil oxidase factor(gene name synonym)|uniprotkb:p67-phox(gene name synonym)|uniprotkb:NCF2(gene name)|psi-mi:NCF2(display_short)	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804520|imex:IM-13779-816	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000116701.16(gene)|ensembl:ENST00000367535.8(transcript)|ensembl:ENST00000367536.5(transcript)|ensembl:ENST00000697330.1(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006801""(superoxide metabolic process)|go:""GO:0006909""(phagocytosis)|go:""GO:0006968""(cellular defense response)|go:""GO:0009055""(electron transfer activity)|go:""GO:0016020""(membrane)|go:""GO:0016175""(""superoxide-generating NAD(P)H oxidase activity"")|go:""GO:0016176""(superoxide-generating NADPH oxidase activator activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032010""(phagolysosome)|go:""GO:0042554""(superoxide anion generation)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0045087""(innate immune response)|go:""GO:0045730""(respiratory burst)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034885|interpro:IPR034889|interpro:IPR035546|interpro:IPR036028|interpro:IPR051864|interpro:IPR053793|mint:P19878|rcsb pdb:1E96|rcsb pdb:1HH8|rcsb pdb:1K4U|rcsb pdb:1OEY|rcsb pdb:1WM5|rcsb pdb:2DMO|rcsb pdb:8WEJ|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|refseq:NP_000424.2|refseq:NP_001121123.1|refseq:NP_001177718.1|refseq:NP_001177723.1|refseq:XP_011507882.1|refseq:XP_011507883.1|efo:""Orphanet:379""|panther:PTHR15175(orthology-group)|dip:DIP-76N"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UnXrnD0zuJFCfL4g4YPKiskTxzo9606	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	intact-crc:440F9DA61764553B|rigid:aPvza+JSmJPt5vgfsoPFhE/Vjcs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13765	uniprotkb:Q5NH32	intact:EBI-712216|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|intact:EBI-25601473|ensembl:ENSP00000349212.3|ensembl:ENSP00000377469.4|ensembl:ENSP00000446801.1|ensembl:ENSP00000447821.1|ensembl:ENSP00000503345.1|uniprotkb:F8VU71	intact:EBI-2799515	psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name)	psi-mi:ilvd_fratt(display_long)|uniprotkb:FTT_0640(locus name)|uniprotkb:ilvD(gene name)|psi-mi:ilvD(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804562|imex:IM-13779-820	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|ensembl:ENSG00000196531.14(gene)|ensembl:ENST00000356769.7(transcript)|ensembl:ENST00000393891.8(transcript)|ensembl:ENST00000546392.6(transcript)|ensembl:ENST00000552540.5(transcript)|ensembl:ENST00000678066.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003231""(cardiac ventricle development)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005854""(nascent polypeptide-associated complex)|go:""GO:0006412""(translation)|go:""GO:0010664""(negative regulation of striated muscle cell apoptotic process)|go:""GO:0015031""(protein transport)|go:""GO:0042060""(wound healing)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048633""(positive regulation of skeletal muscle tissue growth)|go:""GO:0048742""(regulation of skeletal muscle fiber development)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905551""(negative regulation of protein localization to endoplasmic reticulum)|go:""GO:2000138""(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|rcsb pdb:7QWQ|rcsb pdb:7QWR|rcsb pdb:7QWS|rcsb pdb:8P2K|rcsb pdb:9F1B|rcsb pdb:9F1C|rcsb pdb:9F1D|rcsb pdb:9FQ0|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N"	"interpro:IPR004404(Dihydroxy-acid dehydratase)|interpro:IPR000581(Dihydroxy-acid and 6-phosphogluconate dehydratase)|interpro:IPR020558|refseq:YP_169660.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004160""(dihydroxy-acid dehydratase activity)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|refseq:WP_003020386.1|interpro:IPR037237|interpro:IPR042096|interpro:IPR050165"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/17	rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606	rogid:rp/AkKv3JHJxwOIqAhck+YC5pGc177416	intact-crc:E23DECB1DDA2BAF0|rigid:vaGHzQ1x+4CnYnO5+VLSiy0klFI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFB1	uniprotkb:Q13765	intact:EBI-2804572	intact:EBI-712216|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|intact:EBI-25601473|ensembl:ENSP00000349212.3|ensembl:ENSP00000377469.4|ensembl:ENSP00000446801.1|ensembl:ENSP00000447821.1|ensembl:ENSP00000503345.1|uniprotkb:F8VU71	psi-mi:gpmi_fratt(display_long)|uniprotkb:FTT_1329(locus name)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)	psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804569|imex:IM-13779-822	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|refseq:YP_170281.1|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|refseq:WP_003022072.1|interpro:IPR036646"	"refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|ensembl:ENSG00000196531.14(gene)|ensembl:ENST00000356769.7(transcript)|ensembl:ENST00000393891.8(transcript)|ensembl:ENST00000546392.6(transcript)|ensembl:ENST00000552540.5(transcript)|ensembl:ENST00000678066.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003231""(cardiac ventricle development)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005854""(nascent polypeptide-associated complex)|go:""GO:0006412""(translation)|go:""GO:0010664""(negative regulation of striated muscle cell apoptotic process)|go:""GO:0015031""(protein transport)|go:""GO:0042060""(wound healing)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048633""(positive regulation of skeletal muscle tissue growth)|go:""GO:0048742""(regulation of skeletal muscle fiber development)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905551""(negative regulation of protein localization to endoplasmic reticulum)|go:""GO:2000138""(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|rcsb pdb:7QWQ|rcsb pdb:7QWR|rcsb pdb:7QWS|rcsb pdb:8P2K|rcsb pdb:9F1B|rcsb pdb:9F1C|rcsb pdb:9F1D|rcsb pdb:9FQ0|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/17	rogid:hCl6sKvAA6k+SXkq3rxPT9kGowE177416	rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606	intact-crc:433842B1DD551480|rigid:3KKNtYtM4KybV/fSCbgneHG6bxg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIJ3	uniprotkb:A2RRP1	intact:EBI-2798422|uniprotkb:A0A0G2RM06	intact:EBI-2267264|uniprotkb:O95790|uniprotkb:Q2VPJ7|uniprotkb:Q86V39|uniprotkb:Q8NFY8|uniprotkb:Q9Y3W5|uniprotkb:Q53TK6|intact:EBI-2561349|ensembl:ENSP00000281513.5	psi-mi:q5nij3_fratt(display_long)|uniprotkb:sdhA(gene name)|psi-mi:sdhA(display_short)|uniprotkb:FTT_0074(locus name)	psi-mi:nbas_human(display_long)|uniprotkb:NBAS(gene name)|psi-mi:NBAS(display_short)|uniprotkb:NAG(gene name synonym)|uniprotkb:Neuroblastoma-amplified gene protein(gene name synonym)|uniprotkb:Neuroblastoma-amplified sequence(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804555|imex:IM-13779-821	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0008177""(""succinate dehydrogenase (quinone) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0009061""(anaerobic respiration)|go:""GO:0022900""(electron transport chain)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|refseq:YP_169149.1|interpro:IPR027477|refseq:WP_003019788.1|interpro:IPR036188|interpro:IPR037099|interpro:IPR030664"	"dip:DIP-56726N|ensembl:ENSG00000151779.14(gene)|ensembl:ENST00000281513.10(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0070939""(Dsl1/NZR complex)|go:""GO:2000623""(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013244(Secretory pathway Sec39)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR029145|interpro:IPR054751|reactome:R-HSA-6811434|refseq:NP_056993.2|efo:""Orphanet:391677""|efo:""Orphanet:464724""|panther:PTHR15922(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:sDR33MuGlwHfY9HuZdMhwuYSZI8177416	rogid:sxaeSd5hYMpu41GQ+C6X8hMeqjM9606	intact-crc:B2A25FE4B1448CE9|rigid:WkZ4jhw8cdjmZlC3UrURrCDSVKs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q58F05	uniprotkb:Q5NFQ6	intact:EBI-2804544	intact:EBI-2803494	psi-mi:q58f05_human(display_long)|uniprotkb:NARG1(gene name)|psi-mi:NARG1(display_short)	psi-mi:q5nfq6_fratt(display_long)|uniprotkb:FTT_1170(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804548|imex:IM-13779-819	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|go:""GO:0005737""(cytoplasm)"	"interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:YP_170136.1|go:""GO:0016020""(membrane)|go:""GO:0036503""(ERAD pathway)|interpro:IPR050767"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gGm/TG9xqkwXmOWMLKgLoqXYLEc9606	rogid:Rw7n2+NGU7uN8LMwBodXD4RI7s4177416	intact-crc:8B2DB0A4A410CD2C|rigid:aBlbTiDTzjJjRaNN98uT5tNzHH4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86UW6	uniprotkb:Q5NET8	intact:EBI-2804583|uniprotkb:Q9NVK2|uniprotkb:Q9P2D4|uniprotkb:A0AVR3|intact:EBI-28972272|ensembl:ENSP00000261435.6	intact:EBI-2797750|uniprotkb:A0A0G2RM76	psi-mi:n4bp2_human(display_long)|uniprotkb:B3BP(gene name synonym)|uniprotkb:KIAA1413(gene name synonym)|uniprotkb:BCL-3-binding protein(gene name synonym)|uniprotkb:N4BP2(gene name)|psi-mi:N4BP2(display_short)	psi-mi:q5net8_fratt(display_long)|uniprotkb:hrpA(gene name)|psi-mi:hrpA(display_short)|uniprotkb:FTT_1524c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804580|imex:IM-13779-823	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011512020.1|refseq:NP_060647.2|refseq:NP_001305288.1|refseq:XP_016863887.1|ensembl:ENSG00000078177.15(gene)|ensembl:ENST00000261435.11(transcript)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004520""(DNA endonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0046404""(ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity)|interpro:IPR002625(Smr protein/MutS2 C-terminal)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR013899(Region of unknown function DUF1771)|interpro:IPR027417|interpro:IPR036063|interpro:IPR041801|interpro:IPR052772|rcsb pdb:2D9I|rcsb pdb:2VKC|rcsb pdb:3BHB|rcsb pdb:3FAU|panther:PTHR46535(orthology-group)"	"go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170454.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR024590|interpro:IPR010222(RNA helicase, ATP-dependent DEAH box, HrpA type)|interpro:IPR027417|refseq:WP_003022403.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SjG6xFHDSeW//hSDpVlz7DwdtrY9606	rogid:dwTrOZ+V/pe0RndqVFMFAdvwFAM177416	intact-crc:1CD11518D27FFB2D|rigid:+qfwPlrdhhRP/sfiRU6wAJ2HQL8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID9	uniprotkb:Q13459	intact:EBI-2798201	intact:EBI-721429|uniprotkb:O75314|uniprotkb:Q9NUJ2|uniprotkb:Q9UHN0|ensembl:ENSP00000507803.1	psi-mi:eftu_fratt(display_long)|uniprotkb:FTT_0137(locus name)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)	psi-mi:myo9b_human(display_long)|uniprotkb:Unconventional myosin-9b(gene name synonym)|uniprotkb:MYO9B(gene name)|psi-mi:MYO9B(display_short)|uniprotkb:MYR5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804609|imex:IM-13779-826	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0097216""(guanosine tetraphosphate binding)|refseq:YP_169203.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR033720|interpro:IPR031157|refseq:WP_003028672.1|interpro:IPR041709|interpro:IPR050055"	"refseq:NP_004136.2|ensembl:ENSG00000099331.14(gene)|ensembl:ENST00000682292.1(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0001726""(ruffle)|go:""GO:0003779""(actin binding)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|interpro:IPR029071|go:""GO:0005938""(cell cortex)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016459""(myosin complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0043531""(ADP binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048495""(Roundabout binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR036023|interpro:IPR036961|interpro:IPR046349|interpro:IPR046987|interpro:IPR046989|mint:Q13459|rcsb pdb:5C5S|rcsb pdb:5HPY|reactome:R-HSA-2029482|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9035034|reactome:R-HSA-9664422|panther:PTHR46184(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h5xJZCtwL77bt8cg/p85MmX1c+E177416	rogid:eY7IjP7HSaKQaY4g77HcQYMPmyo9606	intact-crc:9F8B3DFCB930F159|rigid:wm2M8A/Vb3YgCTQllI5fhFJljRk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGX7	uniprotkb:Q9NPC6	intact:EBI-2801615	intact:EBI-746712|ensembl:ENSP00000306997.6|uniprotkb:O43415|uniprotkb:Q9HB92	psi-mi:pnp_fratt(display_long)|uniprotkb:Polynucleotide phosphorylase(gene name synonym)|uniprotkb:FTT_0699(locus name)|uniprotkb:pnp(gene name)|psi-mi:pnp(display_short)	psi-mi:myoz2_human(display_long)|uniprotkb:Calsarcin-1(gene name synonym)|uniprotkb:FATZ-related protein 2(gene name synonym)|uniprotkb:MYOZ2(gene name)|psi-mi:MYOZ2(display_short)|uniprotkb:C4orf5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804602|imex:IM-13779-824	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169715.1|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR020568|interpro:IPR027408|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004654""(polyribonucleotide nucleotidyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0006402""(mRNA catabolic process)|refseq:WP_003020501.1|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612"	"ensembl:ENSG00000172399.6(gene)|ensembl:ENST00000307128.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003779""(actin binding)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030017""(sarcomere)|go:""GO:0030018""(Z disc)|go:""GO:0030346""(protein phosphatase 2B binding)|go:""GO:0031433""(telethonin binding)|go:""GO:0043503""(skeletal muscle fiber adaptation)|go:""GO:0045214""(sarcomere organization)|go:""GO:0051373""(FATZ binding)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR008438(Calcineurin-binding)|refseq:NP_057683.1|panther:PTHR15941(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0NGzY8LkmfRcwKNJb6ydU4X1Qxs177416	rogid:Y2B5tDM2oGscI8xiTwB69hFEhL89606	intact-crc:4F5AD89B0897698F|rigid:arg0FNIq1qOKnE50+5jPqKQdaDI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14974	uniprotkb:Q5NEW4	intact:EBI-351726|uniprotkb:Q2NKL4|uniprotkb:Q569H0|uniprotkb:Q86WU3|uniprotkb:Q8NFR6|uniprotkb:Q9BYH0|intact:EBI-28988491|uniprotkb:B4DZ09|uniprotkb:F8VWB4|ensembl:ENSP00000261207.5|ensembl:ENSP00000389168.2	intact:EBI-2804278|uniprotkb:A0A0G2RNG0	psi-mi:mypt1_human(display_long)|uniprotkb:PPP1R12A(gene name)|psi-mi:PPP1R12A(display_short)|uniprotkb:MBS(gene name synonym)|uniprotkb:MYPT1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym)	psi-mi:q5new4_fratt(display_long)|uniprotkb:FTT_1493c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804595|imex:IM-13779-825	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137357.1|refseq:NP_001137358.1|refseq:NP_002471.1|refseq:NP_001231919.1|refseq:NP_001231921.1|refseq:XP_011536685.1|ensembl:ENSG00000058272.19(gene)|ensembl:ENST00000261207.9(transcript)|ensembl:ENST00000450142.7(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0001725""(stress fiber)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0017020""(myosin phosphatase regulator activity)|go:""GO:0019208""(phosphatase regulator activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0031672""(A band)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043292""(contractile muscle fiber)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046822""(regulation of nucleocytoplasmic transport)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR031775|interpro:IPR036770|interpro:IPR051226|mint:O14974|rcsb pdb:2KJY|rcsb pdb:5HUZ|reactome:R-HSA-2565942|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|dip:DIP-33186N|panther:PTHR24179(orthology-group)"	refseq:YP_170428.1|refseq:WP_003022358.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:Xi5lGskc0tWQCHtbYlgR45ERMSk9606	rogid:27huGXtUR7EE86YZGD/S43e1SDg177416	intact-crc:24AED92C8087900A|rigid:58V1K6EJsGq+ZfEuPOTWtUuhJ7U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35579	uniprotkb:Q5NGV7	intact:EBI-350338|uniprotkb:O60805|uniprotkb:Q86T83|intact:EBI-1054343|intact:EBI-25631636|uniprotkb:A8K6E4|uniprotkb:Q60FE2|ensembl:ENSP00000216181.6	intact:EBI-2796192	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:katg_fratt(display_long)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:FTT_0721c(locus name)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804627|imex:IM-13779-829	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:182050""|efo:""Orphanet:477742""|efo:""Orphanet:90635""|ensembl:ENSG00000100345.23(gene)|ensembl:ENST00000216181.11(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000212""(meiotic spindle organization)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0001931""(uropod)|go:""GO:0003723""(RNA binding)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005826""(actomyosin contractile ring)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016604""(nuclear body)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030220""(platelet formation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032418""(lysosome localization)|go:""GO:0032506""(cytokinetic process)|go:""GO:0032796""(uropod organization)|go:""GO:0032982""(myosin filament)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042641""(actomyosin)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043531""(ADP binding)|go:""GO:0043534""(blood vessel endothelial cell migration)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051015""(actin filament binding)|go:""GO:0051295""(establishment of meiotic spindle localization)|go:""GO:0060471""(cortical granule exocytosis)|go:""GO:0060473""(cortical granule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097513""(myosin II filament)|go:""GO:1903919""(negative regulation of actin filament severing)|go:""GO:1903923""(positive regulation of protein processing in phagocytic vesicle)|go:""GO:1905684""(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|reactome:R-HSA-9725370|refseq:NP_002464.1|refseq:XP_011528499.1|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|panther:PTHR45615(orthology-group)"	"refseq:YP_169735.1|interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|refseq:WP_003020536.1|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	rogid:UVLspYdPWJwb7VPBG0xNq1Pp2KQ177416	intact-crc:94532C4A10D1B817|rigid:8vhSQxdnDcCgywLP55S7GzVtUlk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF74	uniprotkb:O75592	intact:EBI-2796785|uniprotkb:A0A0G2RND4	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596.2	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804648|imex:IM-13779-830	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"refseq:NP_055872.4|dip:DIP-28142N|ensembl:ENSG00000005810.20(gene)|ensembl:ENST00000544440.7(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030424""(axon)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902667""(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|panther:PTHR45943(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:DD26E0CC0CFD2554|rigid:aRQbE52e8RzaCd6GIQ9nbjfH8i8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N699	uniprotkb:Q5NEJ4	intact:EBI-2804634|uniprotkb:Q9H763|uniprotkb:Q8N396|uniprotkb:Q8TBE8|ensembl:ENSP00000356214.5	intact:EBI-2799894|uniprotkb:A0A0G2RQA6	psi-mi:myct1_human(display_long)|uniprotkb:MTLC(gene name synonym)|uniprotkb:MTMC1(gene name synonym)|uniprotkb:Myc target in myeloid cells protein 1(gene name synonym)|uniprotkb:MYCT1(gene name)|psi-mi:MYCT1(display_short)	psi-mi:q5nej4_fratt(display_long)|uniprotkb:ftsK(gene name)|psi-mi:ftsK(display_short)|uniprotkb:FTT_1635(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804641|imex:IM-13779-828	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011534451.1|refseq:XP_011534452.1|refseq:XP_011534453.1|refseq:XP_011534454.1|refseq:NP_079383.2|ensembl:ENSG00000120279.7(gene)|ensembl:ENST00000367245.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016604""(nuclear body)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|interpro:IPR029180|mint:Q8N699|refseq:XP_016866808.1|panther:PTHR14869(orthology-group)"	"interpro:IPR002543(Cell divisionFtsK/SpoIIIE)|interpro:IPR018541|refseq:YP_170548.1|interpro:IPR027417|interpro:IPR025199|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007059""(chromosome segregation)|go:""GO:0051301""(cell division)|refseq:WP_003022567.1|interpro:IPR036388|interpro:IPR036390|interpro:IPR041027|interpro:IPR050206"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/ppiWzZNtf2iURw/XIZ7ujOyIlQ9606	rogid:MHG0tEU4NHSPB6cp/UeAYw2sOLQ177416	intact-crc:DECE39716BA52918|rigid:p3nckGFmU2OPyAQakmncoR4o7VE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94832	uniprotkb:Q5NFC1	intact:EBI-355634|uniprotkb:Q8NHP9|uniprotkb:A6H8V3|ensembl:ENSP00000324527.5	intact:EBI-2804619|uniprotkb:A0A0G2RQ47	psi-mi:myo1d_human(display_long)|uniprotkb:MYO1D(gene name)|psi-mi:MYO1D(display_short)|uniprotkb:KIAA0727(gene name synonym)	psi-mi:q5nfc1_fratt(display_long)|uniprotkb:Leucine aminopeptidase(gene name synonym)|uniprotkb:Leucyl aminopeptidase(gene name synonym)|uniprotkb:pepA(gene name)|psi-mi:pepA(display_short)|uniprotkb:FTT_1318c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804616|imex:IM-13779-827	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056009.1|ensembl:ENSG00000176658.17(gene)|ensembl:ENST00000318217.10(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005903""(brush border)|go:""GO:0005938""(cell cortex)|go:""GO:0006897""(endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016459""(myosin complex)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030424""(axon)|go:""GO:0030673""(axolemma)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043204""(perikaryon)|go:""GO:0043209""(myelin sheath)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051641""(cellular localization)|go:""GO:0061502""(early endosome to recycling endosome transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097440""(apical dendrite)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O94832|refseq:NP_001290208.1|panther:PTHR13140(orthology-group)"	"interpro:IPR023042|interpro:IPR011356(Peptidase M17, leucyl aminopeptidase)|interpro:IPR000819(Peptidase M17, leucyl aminopeptidase, C-terminal)|interpro:IPR008283(Peptidase M17, leucyl aminopeptidase, N-terminal)|refseq:YP_170271.1|rcsb pdb:3PEI|interpro:IPR043472|go:""GO:0005737""(cytoplasm)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|refseq:WP_003016784.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EjrnXi04BVb6Z59cU3e5LW7EhRI9606	rogid:zmgvN096sZv3fesDbF3AjymhTQo177416	intact-crc:78EB7E26D26841CE|rigid:8nSjrZrM+st88a7ny1cXFuRuKgI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q5NH25	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2801721|uniprotkb:A0A0G2RPF3	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:q5nh25_fratt(display_long)|uniprotkb:rnfB(gene name)|psi-mi:rnfB(display_short)|uniprotkb:FTT_0649c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804676|imex:IM-13779-835	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR010207(Electron transport complex, RnfB)|interpro:IPR007202(Putative Fe-S cluster)|refseq:YP_169667.1|go:""GO:0009055""(electron transfer activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR050294|refseq:WP_003020399.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:sEefqn1hBfQKvxFloQ/gU9toQGA177416	intact-crc:00CE112ACBA3B3BC|rigid:LmtpvY6HRNy/1fpmJgCeiQDp/2Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHX5	uniprotkb:P01871	intact:EBI-2801674|uniprotkb:A0A0G2RNV9	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	psi-mi:q5nhx5_fratt(display_long)|uniprotkb:cdsA(gene name)|psi-mi:cdsA(display_short)|uniprotkb:FTT_0318(locus name)	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804662|imex:IM-13779-834	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000374(Phosphatidate cytidylyltransferase)|refseq:YP_169367.1|go:""GO:0004605""(phosphatidate cytidylyltransferase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0016024""(CDP-diacylglycerol biosynthetic process)|refseq:WP_003021609.1"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:j4nia2AICT6hhJFTrk/Er4tDCe8177416	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	intact-crc:5DE4112ACBB6D267|rigid:5jcT9p8S/kr1RsET0q6k4PWKo74	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGF1	uniprotkb:P01871	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804683|imex:IM-13779-833	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	intact-crc:8EA3CE2ACAC3CEFC|rigid:42MDIWCTdyAmehdHiDzga5sPgvE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q5NHM9	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2800895	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:q5nhm9_fratt(display_long)|uniprotkb:glyQ(gene name)|psi-mi:glyQ(display_short)|uniprotkb:Glycyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:FTT_0419(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804669|imex:IM-13779-832	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"interpro:IPR006194(Glycyl-tRNA synthetase, class II, heterodimeric)|interpro:IPR002310(Glycyl-tRNA synthetase, class IIc, alpha subunit)|refseq:YP_169463.1|go:""GO:0004820""(glycine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006426""(glycyl-tRNA aminoacylation)|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:gK04DTuny1DO8Bpf570jc75RJkg177416	intact-crc:3E41112AC82634BC|rigid:XgFDu93YCs7eLbzqUYUJt11TdYc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92614	uniprotkb:Q5NEB4	intact:EBI-949059|uniprotkb:Q5H9U3|uniprotkb:Q5W9F9|uniprotkb:Q5W9G1|uniprotkb:Q8IXP8|intact:EBI-25627010|uniprotkb:Q5QD01|ensembl:ENSP00000437073.1	intact:EBI-2797653|uniprotkb:A0A0G2RPR1	psi-mi:my18a_human(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym)|uniprotkb:TIAF1(gene name synonym)	psi-mi:q5neb4_fratt(display_long)|uniprotkb:yegQ(gene name)|psi-mi:yegQ(display_short)|uniprotkb:FTT_1726(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804655|imex:IM-13779-831	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-46631N|refseq:NP_510880.2|refseq:NP_976063.1|refseq:NP_001333696.1|refseq:NP_001333697.1|ensembl:ENSG00000196535.20(gene)|ensembl:ENST00000527372.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0006259""(DNA metabolic process)|go:""GO:0007030""(Golgi organization)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016477""(cell migration)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032982""(myosin filament)|go:""GO:0042641""(actomyosin)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043531""(ADP binding)|go:""GO:0048194""(Golgi vesicle budding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051015""(actin filament binding)|go:""GO:0090161""(Golgi ribbon formation)|go:""GO:0090164""(asymmetric Golgi ribbon formation)|go:""GO:1903028""(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR020587|interpro:IPR027417|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|interpro:IPR041489|mint:Q92614|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|panther:PTHR45615(orthology-group)"	"interpro:IPR001539(Peptidase U32)|refseq:YP_170628.1|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|interpro:IPR032525|refseq:WP_003022701.1|interpro:IPR051454"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:IunEYt79RO62wU6VU2gv16Xb7Lk9606	rogid:V8v+igazfnHs0EcKm43UGRWNmrY177416	intact-crc:1C3BECE5BE2FFF87|rigid:/DziTsFxFxDMWHo5+a7sXgKO/zE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q5NFV6	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2797055|uniprotkb:A0A0G2RM43	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:q5nfv6_fratt(display_long)|uniprotkb:rpoH(gene name)|psi-mi:rpoH(display_short)|uniprotkb:RNA polymerase sigma-32 factor(gene name synonym)|uniprotkb:FTT_1112c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804690|imex:IM-13779-838	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0009408""(response to heat)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0016987""(sigma factor activity)|refseq:YP_170086.1|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012759(RNA polymerase sigma factor RpoH, proteobacteria)|refseq:WP_003021274.1|interpro:IPR050813"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:TUiRpVCoti/MNhIPmxh1x7nUv4Q177416	intact-crc:AE6EBF2ACB50FD39|rigid:UQ5/Gzk+aoU3GoZ1O+pDjDUd9Sg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:P01871	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804711|imex:IM-13779-837	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	intact-crc:96AC2C2ACA9E1E3E|rigid:M0erJzOIq6Hh8J+Em1IcsTO2zAQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q5NEX3	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2797977|uniprotkb:A0A0G2RMN5	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:q5nex3_fratt(display_long)|uniprotkb:aceF(gene name)|psi-mi:aceF(display_short)|uniprotkb:FTT_1484c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804704|imex:IM-13779-839	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006086""(pyruvate decarboxylation to acetyl-CoA)|go:""GO:0006096""(glycolytic process)|go:""GO:0031405""(lipoic acid binding)|go:""GO:0045254""(pyruvate dehydrogenase complex)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR006256(Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|refseq:YP_170419.1|refseq:WP_003022341.1|interpro:IPR023213|interpro:IPR036625|interpro:IPR050743"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:YXI43uZwUchXxoDxiv+5yFM3SDk177416	intact-crc:FEA72C2ACA7CD2B8|rigid:jxO3JI2B7RZPiUfTcxTnWK3xP4k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q5NFR9	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2796367|uniprotkb:A0A0G2RN39	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:q5nfr9_fratt(display_long)|uniprotkb:pilQ(gene name)|psi-mi:pilQ(display_short)|uniprotkb:FTT_1156c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804697|imex:IM-13779-836	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009306""(protein secretion)|interpro:IPR001775(Bacterial general secretion pathway protein D)|interpro:IPR005644(NolW-like)|interpro:IPR013355(Type IV pilus secretin PilQ)|interpro:IPR011662(Secretin/TonB, short N-terminal)|interpro:IPR004846(Type II and III secretion system)|interpro:IPR004845(Type II secretion system gspD, conserved site)|refseq:YP_170123.1|refseq:WP_003021368.1|interpro:IPR038591|interpro:IPR051808"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:5Bv1oL/eG4begMb5a4sn4z1n/jk177416	intact-crc:84AABF2AC8208961|rigid:xqFQM0vClL7rDWYq1PXmnUR2xrU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q04900	uniprotkb:Q5NGA0	intact:EBI-2115896|uniprotkb:Q5JSU6|uniprotkb:E1P5E8|uniprotkb:E1P5E7|uniprotkb:E1P5E9|uniprotkb:B4DQ85|uniprotkb:O95413|uniprotkb:Q9BPV0|uniprotkb:Q9NR26|ensembl:ENSP00000309376.4	intact:EBI-2800784|uniprotkb:A0A0G2RQ90	psi-mi:muc24_human(display_long)|uniprotkb:Endolyn(gene name synonym)|uniprotkb:CD164(gene name)|psi-mi:CD164(display_short)|uniprotkb:Multi-glycosylated core protein 24(gene name synonym)	psi-mi:q5nga0_fratt(display_long)|uniprotkb:rhlE(gene name)|psi-mi:rhlE(display_short)|uniprotkb:FTT_0952(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804718|imex:IM-13779-842	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11337(orthology-group)|efo:""Orphanet:90635""|dip:DIP-43970N|ensembl:ENSG00000135535.17(gene)|ensembl:ENST00000310786.10(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007517""(muscle organ development)|go:""GO:0010008""(endosome membrane)|go:""GO:0030097""(hemopoiesis)|interpro:IPR007947(CD164 related protein)|mint:Q04900|refseq:NP_001135873.1|refseq:NP_001135874.1|refseq:NP_001135875.1|refseq:NP_001135876.1|refseq:NP_001333429.1|refseq:NP_006007.2"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|refseq:YP_169942.1|interpro:IPR027417|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0016787""(hydrolase activity)|refseq:WP_003021019.1|interpro:IPR050079"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RnECOHDDKJ98oN/MPUzPHIwRePs9606	rogid:IIfGlhg/cfRi88KrQNS1limaOMY177416	intact-crc:BBC7B1AD622CF688|rigid:LdD6PJIGG0TukqFjaDhgzqP5ef4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV3	uniprotkb:P52701	intact:EBI-2797317	intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9|ensembl:ENSP00000234420.5	psi-mi:q5ngv3_fratt(display_long)|uniprotkb:FTT_0726c(locus name)	psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804751|imex:IM-13779-843	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0006629""(lipid metabolic process)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|interpro:IPR017946|refseq:YP_169739.1|interpro:IPR030395|refseq:WP_003020543.1"	"panther:PTHR11361(orthology-group)|ensembl:ENSG00000116062.19(gene)|ensembl:ENST00000234420.11(transcript)|go:""GO:0000710""(meiotic mismatch repair)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006298""(mismatch repair)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009411""(response to UV)|go:""GO:0016446""(somatic hypermutation of immunoglobulin genes)|go:""GO:0016447""(somatic recombination of immunoglobulin gene segments)|go:""GO:0019899""(enzyme binding)|go:""GO:0030983""(mismatched DNA binding)|go:""GO:0032137""(guanine/thymine mispair binding)|go:""GO:0032301""(MutSalpha complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045190""(isotype switching)|go:""GO:0045910""(negative regulation of DNA recombination)|go:""GO:0051096""(positive regulation of helicase activity)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|interpro:IPR045076|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|rcsb pdb:8AG6|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|refseq:NP_000170.1|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|efo:""Orphanet:144""|efo:""Orphanet:252202""|dip:DIP-32972N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:3e+5yrpF/Mx2IYeXH2egqOFVYbs177416	rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606	intact-crc:862BB944380A2BAD|rigid:rFZ8431/mRv9zTQwL5Trl9aFmhA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGW2	uniprotkb:P15941	intact:EBI-2796474|uniprotkb:A0A0G2RND5	intact:EBI-2804728|uniprotkb:Q6S4Y3|uniprotkb:Q7Z547|uniprotkb:Q7Z552|uniprotkb:P17626|uniprotkb:Q9UE76|uniprotkb:Q16442|uniprotkb:Q16615|uniprotkb:Q9Y4J2|uniprotkb:Q9UE75|uniprotkb:P13931|uniprotkb:Q9UQL1|uniprotkb:Q9BXA4|uniprotkb:P15942|uniprotkb:Q16437|uniprotkb:Q14128|uniprotkb:Q14876|uniprotkb:B1AVQ8|uniprotkb:B1AVR0|uniprotkb:Q0VAP6|uniprotkb:A6ZID9|uniprotkb:E7EUG9|uniprotkb:Q0VAP5|uniprotkb:Q7Z550|uniprotkb:A5YRV1|uniprotkb:B6ECA1|uniprotkb:E7ESE5|uniprotkb:Q7Z548|uniprotkb:A6ZIE0	psi-mi:q5ngw2_fratt(display_long)|uniprotkb:FTT_0715(locus name)	psi-mi:muc1_human(display_long)|uniprotkb:Krebs von den Lungen-6(gene name synonym)|uniprotkb:PUM(gene name synonym)|uniprotkb:Breast carcinoma-associated antigen DF3(gene name synonym)|uniprotkb:Carcinoma-associated mucin(gene name synonym)|uniprotkb:Episialin(gene name synonym)|uniprotkb:H23AG(gene name synonym)|uniprotkb:PEMT(gene name synonym)|uniprotkb:Peanut-reactive urinary mucin(gene name synonym)|uniprotkb:Polymorphic epithelial mucin(gene name synonym)|uniprotkb:Tumor-associated epithelial membrane antigen(gene name synonym)|uniprotkb:Tumor-associated mucin(gene name synonym)|uniprotkb:MUC1(gene name)|psi-mi:MUC1(display_short)|uniprotkb:Cancer antigen 15-3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804725|imex:IM-13779-840	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0004568""(chitinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR029070|refseq:YP_169730.1|interpro:IPR003610(Carbohydrate-binding family V/XII)|interpro:IPR011583(Chitinase II)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_003020524.1|interpro:IPR036116|interpro:IPR036573|interpro:IPR050314"	"go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0002039""(p53 binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0031982""(vesicle)|go:""GO:0033629""(negative regulation of cell adhesion mediated by integrin)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR000082(SEA)|interpro:IPR036364|mint:P15941|rcsb pdb:1SM3|rcsb pdb:2ACM|rcsb pdb:2FO4|rcsb pdb:5T6P|rcsb pdb:5T78|rcsb pdb:6FZQ|rcsb pdb:6FZR|rcsb pdb:6KX1|rcsb pdb:6TGG|rcsb pdb:7Q4I|rcsb pdb:7V4W|rcsb pdb:7V64|rcsb pdb:7V7K|rcsb pdb:7V8Q|rcsb pdb:7VAC|rcsb pdb:7VAZ|rcsb pdb:8AXH|rcsb pdb:8P6I|reactome:R-HSA-5083625|reactome:R-HSA-5083632|reactome:R-HSA-5083636|reactome:R-HSA-5621480|reactome:R-HSA-6785807|reactome:R-HSA-913709|reactome:R-HSA-977068|refseq:NP_001018016.1|refseq:NP_001018017.1|refseq:NP_001037855.1|refseq:NP_001037856.1|refseq:NP_001037857.1|refseq:NP_001037858.1|refseq:NP_001191214.1|refseq:NP_001191215.1|refseq:NP_001191216.1|refseq:NP_001191217.1|refseq:NP_001191218.1|refseq:NP_001191219.1|refseq:NP_001191220.1|refseq:NP_001191221.1|refseq:NP_001191222.1|refseq:NP_001191223.1|refseq:NP_001191224.1|refseq:NP_001191225.1|refseq:NP_001191226.1|refseq:NP_002447.4|dip:DIP-41890N|efo:""Orphanet:88949""|panther:PTHR10006(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hPHdF34TD5FCXE5bWyEmg/dd7sg177416	rogid:RtvHfzXLy3sZaikeLfDNQeZ/0oY9606	intact-crc:AE8FC994214CAD78|rigid:94YSwOMiqHxuyIaHynOvpeumnlA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHS6	uniprotkb:O75970	intact:EBI-2804758|uniprotkb:A0A0G2RM50	intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|uniprotkb:B2RTS3|ensembl:ENSP00000320006.7|intact:EBI-10961605	psi-mi:q5nhs6_fratt(display_long)|uniprotkb:FTT_0369c(locus name)	psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804761|imex:IM-13779-841	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:YP_169416.1|go:""GO:0036503""(ERAD pathway)|refseq:WP_003020038.1|interpro:IPR050767"	"ensembl:ENSG00000107186.17(gene)|ensembl:ENST00000319217.12(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0030425""(dendrite)|go:""GO:0045177""(apical part of cell)|go:""GO:0120192""(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|interpro:IPR051342|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:NP_003820.2|refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:XP_016870742.1|efo:""Orphanet:269505""|panther:PTHR19964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AZAvG19UziqiyUifSYjwwmYS+LA177416	rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606	intact-crc:4BB2E0960FDE1F3F|rigid:a/JbBuC2z7IfHSlYXPSZi3U/Xpw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID2	uniprotkb:Q9Y605	intact:EBI-2796292	intact:EBI-995714|uniprotkb:B3KVT2|uniprotkb:D3DVT3|ensembl:ENSP00000318352.4|ensembl:ENSP00000372024.4|ensembl:ENSP00000422065.1	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	psi-mi:mofa1_human(display_long)|uniprotkb:PGR1(gene name synonym)|uniprotkb:Protein PGR1(gene name synonym)|uniprotkb:Protein associated with MRG of 14 kDa(gene name synonym)|uniprotkb:MRFAP1(gene name)|psi-mi:MRFAP1(display_short)|uniprotkb:PAM14(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804775|imex:IM-13779-844	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"refseq:NP_150638.1|refseq:NP_001258982.1|ensembl:ENSG00000179010.16(gene)|ensembl:ENST00000320912.8(transcript)|ensembl:ENST00000382581.5(transcript)|ensembl:ENST00000507420.1(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR029254|mint:Q9Y605|panther:PTHR31324(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	rogid:qsRG2MjlSzgcyuUj0/45kBNrfw89606	intact-crc:6AC493E2C07FECF1|rigid:lHd2dzL2Mosm6gqdiEa6TEKAvGE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH45	uniprotkb:Q9Y605	intact:EBI-2796893|uniprotkb:A0A0G2RNJ2	intact:EBI-995714|uniprotkb:B3KVT2|uniprotkb:D3DVT3|ensembl:ENSP00000318352.4|ensembl:ENSP00000372024.4|ensembl:ENSP00000422065.1	psi-mi:q5nh45_fratt(display_long)|uniprotkb:lon(gene name)|psi-mi:lon(display_short)|uniprotkb:ATP-dependent protease La(gene name synonym)|uniprotkb:FTT_0626(locus name)	psi-mi:mofa1_human(display_long)|uniprotkb:PGR1(gene name synonym)|uniprotkb:Protein PGR1(gene name synonym)|uniprotkb:Protein associated with MRG of 14 kDa(gene name synonym)|uniprotkb:MRFAP1(gene name)|psi-mi:MRFAP1(display_short)|uniprotkb:PAM14(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804782|imex:IM-13779-847	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034605""(cellular response to heat)|go:""GO:0043565""(sequence-specific DNA binding)|interpro:IPR054594|refseq:YP_169647.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR027065|interpro:IPR027417|interpro:IPR027543|refseq:WP_003023412.1|mint:Q5NH45|interpro:IPR046336"	"refseq:NP_150638.1|refseq:NP_001258982.1|ensembl:ENSG00000179010.16(gene)|ensembl:ENST00000320912.8(transcript)|ensembl:ENST00000382581.5(transcript)|ensembl:ENST00000507420.1(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR029254|mint:Q9Y605|panther:PTHR31324(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VbLPJiXznE9s4Ww3dtsvWlgjMfM177416	rogid:qsRG2MjlSzgcyuUj0/45kBNrfw89606	intact-crc:3649E2E2C1FBE0EA|rigid:R2lfou6gMmjra5BzVudAmk4iy7c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEG0	uniprotkb:O75970	intact:EBI-2798280	intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|uniprotkb:B2RTS3|ensembl:ENSP00000320006.7|intact:EBI-10961605	psi-mi:q5neg0_fratt(display_long)|uniprotkb:FTT_1676(locus name)	psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804768|imex:IM-13779-846	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_170582.1|refseq:WP_003022628.1	"ensembl:ENSG00000107186.17(gene)|ensembl:ENST00000319217.12(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0030425""(dendrite)|go:""GO:0045177""(apical part of cell)|go:""GO:0120192""(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|interpro:IPR051342|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:NP_003820.2|refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:XP_016870742.1|efo:""Orphanet:269505""|panther:PTHR19964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:D9zHvTFwh7040lhfI799Inv1GbA177416	rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606	intact-crc:AA25DD960E10A3EA|rigid:E6P6HRyKNbDwWGAOMGnNZG4eWF4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI93	uniprotkb:P26038	intact:EBI-2796455|uniprotkb:A0A0G2RN73	intact:EBI-528768|ensembl:ENSP00000353408.5	psi-mi:q5ni93_fratt(display_long)|uniprotkb:ftsZ(gene name)|psi-mi:ftsZ(display_short)|uniprotkb:FTT_0188(locus name)	psi-mi:moes_human(display_long)|uniprotkb:Membrane-organizing extension spike protein(gene name synonym)|uniprotkb:MSN(gene name)|psi-mi:MSN(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804789|imex:IM-13779-845	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000917""(division septum assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|go:""GO:0051258""(protein polymerization)|refseq:YP_169249.1|interpro:IPR020805|interpro:IPR000158(Cell division protein FtsZ, N-terminal)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR037103|interpro:IPR024757|refseq:WP_003017491.1|interpro:IPR036525|interpro:IPR045061"	"ensembl:ENSG00000147065.18(gene)|ensembl:ENST00000360270.7(transcript)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0001931""(uropod)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0022612""(gland morphogenesis)|go:""GO:0022614""(membrane to membrane docking)|go:""GO:0030175""(filopodium)|go:""GO:0031143""(pseudopodium)|go:""GO:0031528""(microvillus membrane)|go:""GO:0031982""(vesicle)|go:""GO:0042098""(T cell proliferation)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050900""(leukocyte migration)|go:""GO:0061028""(establishment of endothelial barrier)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070489""(T cell aggregation)|go:""GO:0071394""(cellular response to testosterone stimulus)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071944""(cell periphery)|go:""GO:0072562""(blood microparticle)|go:""GO:0072678""(T cell migration)|go:""GO:1902115""(regulation of organelle assembly)|go:""GO:1902966""(positive regulation of protein localization to early endosome)|go:""GO:2000401""(regulation of lymphocyte migration)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|interpro:IPR046810|mint:P26038|rcsb pdb:1E5W|rcsb pdb:1EF1|rcsb pdb:1SGH|rcsb pdb:6TXQ|rcsb pdb:6TXS|rcsb pdb:8CIR|rcsb pdb:8CIS|rcsb pdb:8CIT|rcsb pdb:8CIU|reactome:R-HSA-437239|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9725370|refseq:NP_002435.1|dip:DIP-33841N|efo:""Orphanet:504530""|panther:PTHR23281(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:p6oFxKWqOxuojnYBsnj2aLlMQbw177416	rogid:XYzuC8VtaVyNYyZ2G5wVbxyPPww9606	intact-crc:8E5A6A29F1D7FD5D|rigid:C6K6SctqDrRXB6xOBg0u0kYMccg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16539	uniprotkb:Q5NES5	intact:EBI-73946|uniprotkb:A8K6P4|uniprotkb:B0LPH0|uniprotkb:A6ZJ92|uniprotkb:O60776|uniprotkb:Q13083|uniprotkb:Q14084|uniprotkb:Q8TDX0|uniprotkb:B5TY32|ensembl:ENSP00000229794.4	intact:EBI-2797715|uniprotkb:A0A0G2RP44	psi-mi:mk14_human(display_long)|uniprotkb:Mitogen-activated protein kinase p38 alpha(gene name synonym)|uniprotkb:Cytokine suppressive anti-inflammatory drug-binding protein(gene name synonym)|uniprotkb:MAX-interacting protein 2(gene name synonym)|uniprotkb:MAP kinase MXI2(gene name synonym)|uniprotkb:SAPK2A(gene name synonym)|uniprotkb:MAPK14(gene name)|psi-mi:MAPK14(display_short)|uniprotkb:CSBP(gene name synonym)|uniprotkb:CSBP1(gene name synonym)|uniprotkb:CSBP2(gene name synonym)|uniprotkb:CSPB1(gene name synonym)|uniprotkb:MXI2(gene name synonym)|uniprotkb:Stress-activated protein kinase 2a(gene name synonym)	psi-mi:q5nes5_fratt(display_long)|uniprotkb:FTT_1539c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804817|imex:IM-13779-849	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001306.1|refseq:NP_620581.1|refseq:NP_620582.1|refseq:NP_620583.1|panther:PTHR24055(orthology-group)|dip:DIP-30987N|ensembl:ENSG00000112062.13(gene)|ensembl:ENST00000229794.9(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0000922""(spindle pole)|go:""GO:0001502""(cartilage condensation)|go:""GO:0001525""(angiogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001890""(placenta development)|go:""GO:0002021""(response to dietary excess)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0004708""(MAP kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007178""(cell surface receptor protein serine/threonine kinase signaling pathway)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010831""(positive regulation of myotube differentiation)|go:""GO:0016607""(nuclear speck)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019395""(fatty acid oxidation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030168""(platelet activation)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0031098""(stress-activated protein kinase signaling cascade)|go:""GO:0031281""(positive regulation of cyclase activity)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032868""(response to insulin)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046323""(D-glucose import)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048273""(mitogen-activated protein kinase p38 binding)|go:""GO:0048863""(stem cell differentiation)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051525""(NFAT protein binding)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060348""(bone development)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0071493""(cellular response to UV-B)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0090336""(positive regulation of brown fat cell differentiation)|go:""GO:0090398""(cellular senescence)|go:""GO:0090400""(stress-induced premature senescence)|go:""GO:0098586""(cellular response to virus)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099179""(regulation of synaptic membrane adhesion)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1900015""(regulation of cytokine production involved in inflammatory response)|go:""GO:1901741""(positive regulation of myoblast fusion)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038784|interpro:IPR050117|mint:Q16539|rcsb pdb:1A9U|rcsb pdb:1BL6|rcsb pdb:1BL7|rcsb pdb:1BMK|rcsb pdb:1DI9|rcsb pdb:1IAN|rcsb pdb:1KV1|rcsb pdb:1KV2|rcsb pdb:1M7Q|rcsb pdb:1OUK|rcsb pdb:1OUY|rcsb pdb:1OVE|rcsb pdb:1OZ1|rcsb pdb:1R39|rcsb pdb:1R3C|rcsb pdb:1W7H|rcsb pdb:1W82|rcsb pdb:1W83|rcsb pdb:1W84|rcsb pdb:1WBN|rcsb pdb:1WBO|rcsb pdb:1WBS|rcsb pdb:1WBT|rcsb pdb:1WBV|rcsb pdb:1WBW|rcsb pdb:1WFC|rcsb pdb:1YQJ|rcsb pdb:1ZYJ|rcsb pdb:1ZZ2|rcsb pdb:1ZZL|rcsb pdb:2BAJ|rcsb pdb:2BAK|rcsb pdb:2BAL|rcsb pdb:2BAQ|rcsb pdb:2FSL|rcsb pdb:2FSM|rcsb pdb:2FSO|rcsb pdb:2FST|rcsb pdb:2GFS|rcsb pdb:2I0H|rcsb pdb:2LGC|rcsb pdb:2NPQ|rcsb pdb:2OKR|rcsb pdb:2ONL|rcsb pdb:2QD9|rcsb pdb:2RG5|rcsb pdb:2RG6|rcsb pdb:2Y8O|rcsb pdb:2YIS|rcsb pdb:2YIW|rcsb pdb:2YIX|rcsb pdb:2ZAZ|rcsb pdb:2ZB0|rcsb pdb:2ZB1|rcsb pdb:3BV2|rcsb pdb:3BV3|rcsb pdb:3BX5|rcsb pdb:3C5U|rcsb pdb:3CTQ|rcsb pdb:3D7Z|rcsb pdb:3D83|rcsb pdb:3DS6|rcsb pdb:3DT1|rcsb pdb:3E92|rcsb pdb:3E93|rcsb pdb:3FC1|rcsb pdb:3FI4|rcsb pdb:3FKL|rcsb pdb:3FKN|rcsb pdb:3FKO|rcsb pdb:3FL4|rcsb pdb:3FLN|rcsb pdb:3FLQ|rcsb pdb:3FLS|rcsb pdb:3FLW|rcsb pdb:3FLY|rcsb pdb:3FLZ|rcsb pdb:3FMH|rcsb pdb:3FMJ|rcsb pdb:3FMK|rcsb pdb:3FML|rcsb pdb:3FMM|rcsb pdb:3FMN|rcsb pdb:3FSF|rcsb pdb:3FSK|rcsb pdb:3GC7|rcsb pdb:3GCP|rcsb pdb:3GCQ|rcsb pdb:3GCS|rcsb pdb:3GCU|rcsb pdb:3GCV|rcsb pdb:3GFE|rcsb pdb:3GI3|rcsb pdb:3HA8|rcsb pdb:3HEC|rcsb pdb:3HEG|rcsb pdb:3HL7|rcsb pdb:3HLL|rcsb pdb:3HP2|rcsb pdb:3HP5|rcsb pdb:3HRB|rcsb pdb:3HUB|rcsb pdb:3HUC|rcsb pdb:3HV3|rcsb pdb:3HV4|rcsb pdb:3HV5|rcsb pdb:3HV6|rcsb pdb:3HV7|rcsb pdb:3HVC|rcsb pdb:3IPH|rcsb pdb:3ITZ|rcsb pdb:3IW5|rcsb pdb:3IW6|rcsb pdb:3IW7|rcsb pdb:3IW8|rcsb pdb:3K3I|rcsb pdb:3K3J|rcsb pdb:3KF7|rcsb pdb:3KQ7|rcsb pdb:3L8S|rcsb pdb:3L8X|rcsb pdb:3LFA|rcsb pdb:3LFB|rcsb pdb:3LFC|rcsb pdb:3LFD|rcsb pdb:3LFE|rcsb pdb:3LFF|rcsb pdb:3LHJ|rcsb pdb:3MGY|rcsb pdb:3MH0|rcsb pdb:3MH1|rcsb pdb:3MH2|rcsb pdb:3MH3|rcsb pdb:3MPA|rcsb pdb:3MPT|rcsb pdb:3MVL|rcsb pdb:3MVM|rcsb pdb:3MW1|rcsb pdb:3NEW|rcsb pdb:3NNU|rcsb pdb:3NNV|rcsb pdb:3NNW|rcsb pdb:3NNX|rcsb pdb:3NWW|rcsb pdb:3O8P|rcsb pdb:3O8T|rcsb pdb:3O8U|rcsb pdb:3OBG|rcsb pdb:3OBJ|rcsb pdb:3OC1|rcsb pdb:3OCG|rcsb pdb:3OD6|rcsb pdb:3ODY|rcsb pdb:3ODZ|rcsb pdb:3OEF|rcsb pdb:3PG3|rcsb pdb:3QUD|rcsb pdb:3QUE|rcsb pdb:3RIN|rcsb pdb:3ROC|rcsb pdb:3S3I|rcsb pdb:3S4Q|rcsb pdb:3U8W|rcsb pdb:3UVP|rcsb pdb:3UVQ|rcsb pdb:3UVR|rcsb pdb:3ZS5|rcsb pdb:3ZSG|rcsb pdb:3ZSH|rcsb pdb:3ZSI|rcsb pdb:3ZYA|rcsb pdb:4A9Y|rcsb pdb:4AA0|rcsb pdb:4AA4|rcsb pdb:4AA5|rcsb pdb:4AAC|rcsb pdb:4DLI|rcsb pdb:4DLJ|rcsb pdb:4E5A|rcsb pdb:4E5B|rcsb pdb:4E6A|rcsb pdb:4E6C|rcsb pdb:4E8A|rcsb pdb:4EH2|rcsb pdb:4EH3|rcsb pdb:4EH4|rcsb pdb:4EH5|rcsb pdb:4EH6|rcsb pdb:4EH7|rcsb pdb:4EH8|rcsb pdb:4EH9|rcsb pdb:4EHV|rcsb pdb:4EWQ|rcsb pdb:4F9W|rcsb pdb:4F9Y|rcsb pdb:4FA2|rcsb pdb:4GEO|rcsb pdb:4KIN|rcsb pdb:4KIP|rcsb pdb:4KIQ|rcsb pdb:4L8M|rcsb pdb:4R3C|rcsb pdb:4ZTH|rcsb pdb:5ETA|rcsb pdb:5ETC|rcsb pdb:5ETF|rcsb pdb:5ETI|rcsb pdb:5ML5|rcsb pdb:5MTX|rcsb pdb:5MTY|rcsb pdb:5MZ3|rcsb pdb:5N63|rcsb pdb:5N64|rcsb pdb:5N65|rcsb pdb:5N66|rcsb pdb:5N67|rcsb pdb:5N68|rcsb pdb:5O8U|rcsb pdb:5O8V|rcsb pdb:5OMG|rcsb pdb:5OMH|rcsb pdb:5TBE|rcsb pdb:5TCO|rcsb pdb:5WJJ|rcsb pdb:5XYX|rcsb pdb:5XYY|rcsb pdb:6ANL|rcsb pdb:6HWT|rcsb pdb:6HWU|rcsb pdb:6HWV|rcsb pdb:6M95|rcsb pdb:6M9L|rcsb pdb:6OHD|rcsb pdb:6QDZ|rcsb pdb:6QE1|rcsb pdb:6QYX|rcsb pdb:6RFO|rcsb pdb:6SFI|rcsb pdb:6SFJ|rcsb pdb:6SFK|rcsb pdb:6SFO|rcsb pdb:6TCA|rcsb pdb:6ZQS|rcsb pdb:6ZWP|rcsb pdb:8A8M|rcsb pdb:8VXE|reactome:R-HSA-168638|reactome:R-HSA-171007|reactome:R-HSA-198753|reactome:R-HSA-2151209|reactome:R-HSA-2559580|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-4420097|reactome:R-HSA-450302|reactome:R-HSA-450341|reactome:R-HSA-450604|reactome:R-HSA-525793|reactome:R-HSA-5668599|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-9662834|reactome:R-HSA-9824585|ensembl:ENSP00000229794.4|ensembl:ENST00000229795.8|ensembl:ENSP00000229795.3|ensembl:ENST00000310795.8|ensembl:ENSP00000308669.4"	refseq:YP_170467.1|rcsb pdb:4QVR|refseq:WP_003022425.1|interpro:IPR049286	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/06	rogid:oI6EOrCDVMQ6FDVBHSiYYoKZHns9606	rogid:kpfKbBGWIto3tLlkeLstE7LIGIg177416	intact-crc:974A50C8EA710DC8|rigid:SpKxmW1QjWuX1GCEvBxO2S6tyMc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40692	uniprotkb:Q5NEL7	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790.3	intact:EBI-2800119|uniprotkb:A0A0G2RPA8	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:q5nel7_fratt(display_long)|uniprotkb:FTT_1609(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804810|imex:IM-13779-851	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:144""|efo:""Orphanet:252202""|ensembl:ENSG00000076242.18(gene)|ensembl:ENST00000231790.8(transcript)|go:""GO:0000289""(""nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0000712""(resolution of meiotic recombination intermediates)|go:""GO:0000795""(synaptonemal complex)|go:""GO:0001673""(male germ cell nucleus)|go:""GO:0003682""(chromatin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005712""(chiasma)|go:""GO:0005715""(late recombination nodule)|go:""GO:0006298""(mismatch repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0007060""(male meiosis chromosome segregation)|go:""GO:0007129""(homologous chromosome pairing at meiosis)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009617""(response to bacterium)|go:""GO:0016020""(membrane)|go:""GO:0016321""(female meiosis chromosome segregation)|go:""GO:0016446""(somatic hypermutation of immunoglobulin genes)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0032137""(guanine/thymine mispair binding)|go:""GO:0032389""(MutLalpha complex)|go:""GO:0043060""(meiotic metaphase I homologous chromosome alignment)|go:""GO:0045141""(meiotic telomere clustering)|go:""GO:0045190""(isotype switching)|go:""GO:0045950""(negative regulation of mitotic recombination)|go:""GO:0048298""(positive regulation of isotype switching to IgA isotypes)|go:""GO:0048304""(positive regulation of isotype switching to IgG isotypes)|go:""GO:0048477""(oogenesis)|go:""GO:0051257""(meiotic spindle midzone assembly)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|rcsb pdb:6WBA|rcsb pdb:6WBB|rcsb pdb:6WBC|rcsb pdb:7M60|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446|refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|refseq:XP_005265220.1|refseq:XP_005265221.1|dip:DIP-27601N|panther:PTHR10073(orthology-group)|ensembl:ENSP00000231790.3|ensembl:ENST00000429117.6|ensembl:ENSP00000407019.2|ensembl:ENST00000435176.5|ensembl:ENSP00000402564.1|ensembl:ENST00000455445.6|ensembl:ENSP00000398272.2|ensembl:ENST00000458205.6|ensembl:ENSP00000402667.2|ensembl:ENST00000466900.6|ensembl:ENSP00000519069.1|ensembl:ENST00000485889.2|ensembl:ENSP00000518946.1|ensembl:ENST00000492474.6|ensembl:ENSP00000518393.1|ensembl:ENST00000536378.5|ensembl:ENSP00000444286.2|ensembl:ENST00000539477.6|ensembl:ENSP00000443665.1|ensembl:ENST00000674019.1|ensembl:ENSP00000501081.1"	"refseq:YP_170525.1|interpro:IPR003453(Protein of unknown function DUF140)|go:""GO:0005548""(phospholipid transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|interpro:IPR030802|refseq:WP_003022530.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:HkwWSDnnvIDr+ZREHxAKGJChNCg177416	intact-crc:5A36329F5037C0C6|rigid:5uv3KD0Ze3By44nG065CExFuxkk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96BY2	uniprotkb:Q5NIN9	intact:EBI-739825|uniprotkb:Q9H833|uniprotkb:Q9HAS1|uniprotkb:B2RDF6|ensembl:ENSP00000298894.4|ensembl:ENSP00000451594.1|ensembl:ENSP00000482284.1|ensembl:ENSP00000486260.1	intact:EBI-2797260|uniprotkb:A0A0G2RMI5	psi-mi:moap1_human(display_long)|uniprotkb:MOAP1(gene name)|psi-mi:MOAP1(display_short)|uniprotkb:PNMA4(gene name synonym)|uniprotkb:Paraneoplastic antigen Ma4(gene name synonym)	psi-mi:q5nin9_fratt(display_long)|uniprotkb:lysA1(gene name)|psi-mi:lysA1(display_short)|uniprotkb:FTT_0027c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804796|imex:IM-13779-850	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_071434.2|ensembl:ENSG00000165943.5(gene)|ensembl:ENSG00000278268.2(gene)|ensembl:ENST00000298894.5(transcript)|ensembl:ENST00000556883.1(transcript)|ensembl:ENST00000616515.2(transcript)|ensembl:ENST00000627896.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0051204""(protein insertion into mitochondrial membrane)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:2000786""(positive regulation of autophagosome assembly)|interpro:IPR026523|interpro:IPR048270|interpro:IPR048271|mint:Q96BY2|rcsb pdb:7LGC|dip:DIP-49959N|panther:PTHR23095(orthology-group)"	"go:""GO:0008836""(diaminopimelate decarboxylase activity)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR022643|interpro:IPR022644|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|refseq:YP_169103.1|interpro:IPR029066|refseq:WP_003022882.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:wQSSosC82m35M8s+YamN1i73wi49606	rogid:QY7TCwwQHpl28YxX5gZokSqUYFU177416	intact-crc:08580A56C7FFA00A|rigid:V3ERzlzFM6OtRPKIR2lwwrjlzH8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV7	uniprotkb:Q96BY2	intact:EBI-2796192	intact:EBI-739825|uniprotkb:Q9H833|uniprotkb:Q9HAS1|uniprotkb:B2RDF6|ensembl:ENSP00000298894.4|ensembl:ENSP00000451594.1|ensembl:ENSP00000482284.1|ensembl:ENSP00000486260.1	psi-mi:katg_fratt(display_long)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:FTT_0721c(locus name)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)	psi-mi:moap1_human(display_long)|uniprotkb:MOAP1(gene name)|psi-mi:MOAP1(display_short)|uniprotkb:PNMA4(gene name synonym)|uniprotkb:Paraneoplastic antigen Ma4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804803|imex:IM-13779-848	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169735.1|interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|refseq:WP_003020536.1|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)"	"refseq:NP_071434.2|ensembl:ENSG00000165943.5(gene)|ensembl:ENSG00000278268.2(gene)|ensembl:ENST00000298894.5(transcript)|ensembl:ENST00000556883.1(transcript)|ensembl:ENST00000616515.2(transcript)|ensembl:ENST00000627896.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0051204""(protein insertion into mitochondrial membrane)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:2000786""(positive regulation of autophagosome assembly)|interpro:IPR026523|interpro:IPR048270|interpro:IPR048271|mint:Q96BY2|rcsb pdb:7LGC|dip:DIP-49959N|panther:PTHR23095(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:UVLspYdPWJwb7VPBG0xNq1Pp2KQ177416	rogid:wQSSosC82m35M8s+YamN1i73wi49606	intact-crc:0EE4A456C4D573F7|rigid:6RSx6v2YfOXXQ7H9jhPE1rsdaKQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96DM3	uniprotkb:Q5NIF4	intact:EBI-2804848|uniprotkb:Q9Y5M0|uniprotkb:Q9BU17|ensembl:ENSP00000269221.2	intact:EBI-2802846	psi-mi:rmc1_human(display_long)|uniprotkb:RMC1(gene name)|psi-mi:RMC1(display_short)|uniprotkb:C18orf8(gene name synonym)|uniprotkb:Colon cancer-associated protein Mic1(gene name synonym)|uniprotkb:MIC1(gene name synonym)|uniprotkb:WD repeat-containing protein 98(gene name synonym)|uniprotkb:WDR98(gene name synonym)	psi-mi:rf3_fratt(display_long)|uniprotkb:FTT_0118(locus name)|uniprotkb:prfC(gene name)|psi-mi:prfC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804854|imex:IM-13779-855	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000141452.11(gene)|ensembl:ENST00000269221.8(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0006914""(autophagy)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035658""(Mon1-Ccz1 complex)|interpro:IPR009755(Colon cancer-associated Mic1-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR040371|interpro:IPR049040|mint:Q96DM3|refseq:NP_001305636.1|refseq:NP_001305637.1|refseq:NP_001305638.1|refseq:NP_037458.3|panther:PTHR12897(orthology-group)"	"interpro:IPR032090|interpro:IPR004548(Peptide chain release factor 3)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:YP_169188.1|interpro:IPR027417|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006449""(regulation of translational termination)|go:""GO:0016149""(translation release factor activity, codon specific)|go:""GO:0016150""(translation release factor activity, codon nonspecific)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR031157|refseq:WP_003019866.1|interpro:IPR038467|interpro:IPR035647|interpro:IPR053905|interpro:IPR041732"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MmWbhxMFUsrztGSOEB4Wht4fZf89606	rogid:exUjAaNXwgX443c8S/YiaeKgFoM177416	intact-crc:51F188078B1496DE|rigid:lsiivA0iQmJIOjSPRRrbs+gvUKQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFQ6	uniprotkb:Q96DM3	intact:EBI-2803494	intact:EBI-2804848|uniprotkb:Q9Y5M0|uniprotkb:Q9BU17|ensembl:ENSP00000269221.2	psi-mi:q5nfq6_fratt(display_long)|uniprotkb:FTT_1170(locus name)	psi-mi:rmc1_human(display_long)|uniprotkb:RMC1(gene name)|psi-mi:RMC1(display_short)|uniprotkb:C18orf8(gene name synonym)|uniprotkb:Colon cancer-associated protein Mic1(gene name synonym)|uniprotkb:MIC1(gene name synonym)|uniprotkb:WD repeat-containing protein 98(gene name synonym)|uniprotkb:WDR98(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804861|imex:IM-13779-853	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:YP_170136.1|go:""GO:0016020""(membrane)|go:""GO:0036503""(ERAD pathway)|interpro:IPR050767"	"ensembl:ENSG00000141452.11(gene)|ensembl:ENST00000269221.8(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0006914""(autophagy)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035658""(Mon1-Ccz1 complex)|interpro:IPR009755(Colon cancer-associated Mic1-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR040371|interpro:IPR049040|mint:Q96DM3|refseq:NP_001305636.1|refseq:NP_001305637.1|refseq:NP_001305638.1|refseq:NP_037458.3|panther:PTHR12897(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Rw7n2+NGU7uN8LMwBodXD4RI7s4177416	rogid:MmWbhxMFUsrztGSOEB4Wht4fZf89606	intact-crc:424F57078BA93256|rigid:GvszrvsPTJNwDx7VwKJz1hp9rdQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF40	uniprotkb:Q96T58	intact:EBI-2804827|uniprotkb:A0A0G2RMS0	intact:EBI-765739|uniprotkb:Q9UQ01|uniprotkb:Q9Y556|uniprotkb:Q9H9A8|uniprotkb:Q9NWH5|ensembl:ENSP00000364912.3|intact:EBI-28975565	psi-mi:q5nf40_fratt(display_long)|uniprotkb:hemD(gene name)|psi-mi:hemD(display_short)|uniprotkb:FTT_1408c(locus name)	psi-mi:mint_human(display_long)|uniprotkb:SPEN homolog(gene name synonym)|uniprotkb:SMART/HDAC1-associated repressor protein(gene name synonym)|uniprotkb:KIAA0929(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:SHARP(gene name synonym)|uniprotkb:SPEN(gene name)|psi-mi:SPEN(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804824|imex:IM-13779-854	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003754(Tetrapyrrole biosynthesis, uroporphyrinogen III synthase)|refseq:YP_170352.1|go:""GO:0004852""(uroporphyrinogen-III synthase activity)|go:""GO:0033014""(tetrapyrrole biosynthetic process)|refseq:WP_003022220.1|interpro:IPR036108"	"efo:""Orphanet:1606""|ensembl:ENSG00000065526.13(gene)|ensembl:ENST00000375759.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034172|interpro:IPR034173|interpro:IPR034174|interpro:IPR034175|interpro:IPR035979|interpro:IPR049093|interpro:IPR049094|interpro:IPR049095|mint:Q96T58|rcsb pdb:1OW1|rcsb pdb:2RT5|rcsb pdb:4P6Q|rcsb pdb:7Z1K|reactome:R-HSA-9013422|refseq:NP_055816.2|dip:DIP-34569N|efo:""Orphanet:662234""|panther:PTHR23189(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:YODOBsaCGuTNeY3jy1fscL6Llfo177416	rogid:m7bdkKVATaG4dkFG/BYXRn4jOIk9606	intact-crc:FF3078AFC75E706A|rigid:VeTvW0B41Q4Eo5iixyLzd0toFw8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94851	uniprotkb:Q5NI66	intact:EBI-2804835|uniprotkb:Q7Z3A8|uniprotkb:D3DQW5|uniprotkb:B4DGZ0|uniprotkb:B7Z849|uniprotkb:G3XAC8|uniprotkb:Q5KTR3|uniprotkb:Q5KTR4|ensembl:ENSP00000494982.1|intact:EBI-30816912|uniprotkb:A0A2R8YFA9|uniprotkb:Q6ZW33|uniprotkb:Q7RTP7|uniprotkb:Q96JU6	intact:EBI-2797252|uniprotkb:A0A0G2RM61	psi-mi:mica2_human(display_long)|uniprotkb:KIAA0750(gene name synonym)|uniprotkb:MICAL2(gene name)|psi-mi:MICAL2(display_short)|uniprotkb:MICAL2PV1(gene name synonym)|uniprotkb:MICAL2PV2(gene name synonym)|uniprotkb:Molecule interacting with CasL protein 2(gene name synonym)|uniprotkb:MICAL C-terminal-like protein(gene name synonym)|uniprotkb:MICALCL(gene name synonym)	psi-mi:q5ni66_fratt(display_long)|uniprotkb:acpA(gene name)|psi-mi:acpA(display_short)|uniprotkb:FTT_0221(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804841|imex:IM-13779-852	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000133816.19(gene)|ensembl:ENST00000646065.1(transcript)|go:""GO:0001947""(heart looping)|go:""GO:0003779""(actin binding)|go:""GO:0004497""(monooxygenase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007507""(heart development)|go:""GO:0016174""(""NAD(P)H oxidase H2O2-forming activity"")|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016709""(""oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"")|go:""GO:0019417""(sulfur oxidation)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0071949""(FAD binding)|go:""GO:0120501""(F-actin monooxygenase activity)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR016103(Fertility inhibition FinO-like)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|interpro:IPR050540|mint:O94851|rcsb pdb:2E9K|rcsb pdb:5SZH|rcsb pdb:5SZI|rcsb pdb:5SZJ|rcsb pdb:5SZK|refseq:XP_016874078.1|refseq:XP_016874079.1|refseq:XP_016874080.1|refseq:NP_001269593.1|refseq:NP_001269594.1|refseq:NP_001269595.1|refseq:NP_001269596.1|refseq:NP_001333221.1|refseq:NP_001333222.1|refseq:NP_001333223.1|refseq:NP_001333224.1|refseq:NP_001333225.1|refseq:NP_001333226.1|refseq:NP_001333227.1|refseq:NP_001333228.1|refseq:NP_001269592.1|refseq:NP_055447.1|panther:PTHR23167(orthology-group)"	"go:""GO:0034480""(phosphatidylcholine phospholipase C activity)|interpro:IPR007312(Phosphoesterase)|refseq:YP_169276.1|refseq:WP_003021808.1|interpro:IPR017850(Alkaline-phosphatase-like, core domain)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8mpCbdXl9ehfeUK1tmIWnKUMqhc9606	rogid:4qC583ToLOkAvm3AlbzGYd39Rt8177416	intact-crc:4815F107A1669A77|rigid:z7LzOnxUQoJ5tKZtTfF6IqptiKw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH68	uniprotkb:P31153	intact:EBI-2804904	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|uniprotkb:B4DN45|ensembl:ENSP00000303147.3	psi-mi:q5nh68_fratt(display_long)|uniprotkb:FTT_0602c(locus name)	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804901|imex:IM-13779-857	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_169624.1|interpro:IPR021956	"ensembl:ENSG00000168906.13(gene)|ensembl:ENST00000306434.8(transcript)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0036094""(small molecule binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048269""(methionine adenosyltransferase complex)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|rcsb pdb:7BHR|rcsb pdb:7BHS|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCF|rcsb pdb:7KCE|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|rcsb pdb:7LNH|rcsb pdb:7RW5|rcsb pdb:7RW7|rcsb pdb:7RWG|rcsb pdb:7RWH|rcsb pdb:7RXV|rcsb pdb:7RXW|rcsb pdb:7RXX|rcsb pdb:8AXZ|rcsb pdb:8OOG|rcsb pdb:8P1T|rcsb pdb:8P1V|rcsb pdb:8P1W|rcsb pdb:8P4H|rcsb pdb:8QDY|rcsb pdb:8QDZ|rcsb pdb:8QE0|rcsb pdb:8QE1|rcsb pdb:8QE2|rcsb pdb:8QE3|rcsb pdb:8XAM|rcsb pdb:8XAR|rcsb pdb:8XB0|reactome:R-HSA-156581|refseq:NP_005902.1|efo:""Orphanet:91387""|panther:PTHR11964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GAlcl4uPZbm6UqGL6284q4pXX4k177416	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	intact-crc:00415CCF0629A483|rigid:cXRlgX4mA2NPPbC6GJ/m3mjy6G4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H1A3	uniprotkb:Q5NII2	intact:EBI-2804879|uniprotkb:Q9H1A2|uniprotkb:Q8NBT8|uniprotkb:Q9BWJ7|uniprotkb:Q9Y390|ensembl:ENSP00000350874.3	intact:EBI-2804321|uniprotkb:A0A0G2RQ93	psi-mi:metl9_human(display_long)|uniprotkb:DREV(gene name synonym)|uniprotkb:DORA reverse strand protein(gene name synonym)|uniprotkb:METTL9(gene name)|psi-mi:METTL9(display_short)|uniprotkb:Methyltransferase-like protein 9(gene name synonym)|uniprotkb:CGI-81(orf name)	psi-mi:q5nii2_fratt(display_long)|uniprotkb:FTT_0086(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804887|imex:IM-13779-856	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001070648.1|refseq:NP_057109.3|refseq:NP_001275588.1|refseq:NP_001275589.1|ensembl:ENSG00000197006.15(gene)|ensembl:ENST00000358154.8(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0032259""(methylation)|go:""GO:0106370""(protein-L-histidine N-pros-methyltransferase activity)|interpro:IPR007884(DREV methyltransferase)|interpro:IPR029063|mint:Q9H1A3|rcsb pdb:7Y9C|rcsb pdb:7YF2|rcsb pdb:7YF3|rcsb pdb:7YF4|rcsb pdb:8GZE|rcsb pdb:8GZF|panther:PTHR12890(orthology-group)"	"interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR006314(Dyp-type peroxidase)|refseq:YP_169160.1|go:""GO:0004601""(peroxidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0046872""(metal ion binding)|refseq:WP_003019812.1|interpro:IPR048328"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y+kS5qY2f6iIp5xTPC58cOoZfVg9606	rogid:+LH1WQceEflVrrfjPoxm4EmXWgc177416	intact-crc:4084EDEE7A2C78B7|rigid:EaYNJyVSlr1yb+PI1rHVfXwHO+w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHR1	uniprotkb:P31153	intact:EBI-2796649|uniprotkb:A0A0G2RNS1	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|uniprotkb:B4DN45|ensembl:ENSP00000303147.3	psi-mi:q5nhr1_fratt(display_long)|uniprotkb:nadM(gene name)|psi-mi:nadM(display_short)|uniprotkb:FTT_0386(locus name)	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804894|imex:IM-13779-859	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000166""(nucleotide binding)|go:""GO:0000309""(nicotinamide-nucleotide adenylyltransferase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|rcsb pdb:2QJT|rcsb pdb:2R5W|refseq:YP_169431.1|interpro:IPR004821(Cytidyltransferase-related)|refseq:WP_003020070.1|interpro:IPR041750"	"ensembl:ENSG00000168906.13(gene)|ensembl:ENST00000306434.8(transcript)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0036094""(small molecule binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048269""(methionine adenosyltransferase complex)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|rcsb pdb:7BHR|rcsb pdb:7BHS|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCF|rcsb pdb:7KCE|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|rcsb pdb:7LNH|rcsb pdb:7RW5|rcsb pdb:7RW7|rcsb pdb:7RWG|rcsb pdb:7RWH|rcsb pdb:7RXV|rcsb pdb:7RXW|rcsb pdb:7RXX|rcsb pdb:8AXZ|rcsb pdb:8OOG|rcsb pdb:8P1T|rcsb pdb:8P1V|rcsb pdb:8P1W|rcsb pdb:8P4H|rcsb pdb:8QDY|rcsb pdb:8QDZ|rcsb pdb:8QE0|rcsb pdb:8QE1|rcsb pdb:8QE2|rcsb pdb:8QE3|rcsb pdb:8XAM|rcsb pdb:8XAR|rcsb pdb:8XB0|reactome:R-HSA-156581|refseq:NP_005902.1|efo:""Orphanet:91387""|panther:PTHR11964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v8OJ3BBWp0VQq3SVW6XmvR1CP08177416	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	intact-crc:60C55CCF0484EC12|rigid:IabwyMPJ6eC1PyVtPyOHbQRa+nI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHR0	uniprotkb:Q8IWA4	intact:EBI-2804868	intact:EBI-1048197|uniprotkb:D3DNR6|uniprotkb:O60639|uniprotkb:Q9BZB5|uniprotkb:Q9NWQ2|uniprotkb:O15323|uniprotkb:B2RAR1|ensembl:ENSP00000263969.5|ensembl:ENSP00000420617.1|uniprotkb:A0A0C4DFN1	psi-mi:glmu_fratt(display_long)|uniprotkb:FTT_0387(locus name)|uniprotkb:glmU(gene name)|psi-mi:glmU(display_short)	psi-mi:mfn1_human(display_long)|uniprotkb:Transmembrane GTPase MFN1(gene name synonym)|uniprotkb:Fzo homolog(gene name synonym)|uniprotkb:MFN1(gene name)|psi-mi:MFN1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804872|imex:IM-13779-858	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005882(UDP-N-acetylglucosamine pyrophosphorylase)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR018357|interpro:IPR011004(Trimeric LpxA-like)|refseq:YP_169432.1|interpro:IPR025877|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003977""(UDP-N-acetylglucosamine diphosphorylase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019134""(glucosamine-1-phosphate N-acetyltransferase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR029044|interpro:IPR038009|interpro:IPR050065|refseq:WP_003027098.1"	"refseq:NP_284941.2|ensembl:ENSG00000171109.19(gene)|ensembl:ENST00000263969.9(transcript)|ensembl:ENST00000471841.6(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0008053""(mitochondrial fusion)|go:""GO:0010918""(positive regulation of mitochondrial membrane potential)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0046039""(GTP metabolic process)|go:""GO:0051646""(mitochondrion localization)|go:""GO:0098799""(outer mitochondrial membrane protein complex)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR006884(Fzo-like conserved region)|interpro:IPR027094|interpro:IPR027417|interpro:IPR030381|interpro:IPR045063|mint:Q8IWA4|rcsb pdb:5GNR|rcsb pdb:5GNS|rcsb pdb:5GNT|rcsb pdb:5GNU|rcsb pdb:5GO4|rcsb pdb:5GOE|rcsb pdb:5GOF|rcsb pdb:5GOM|rcsb pdb:5YEW|reactome:R-HSA-5205685|reactome:R-HSA-9013419|reactome:R-HSA-983231|refseq:XP_005247653.2|dip:DIP-50289N|panther:PTHR10465(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:u55iLVubTfB1g8ht4JIk53ncUmQ177416	rogid:JqGBpXDIjWiNwJCt2/DOzE7wFxM9606	intact-crc:2A5F962EC0DEC943|rigid:H2njC1blCg4jaFINnTX6ZsBSHVM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHL4	uniprotkb:Q12866	intact:EBI-2804916|uniprotkb:A0A0G2RNY8	intact:EBI-2804911|uniprotkb:Q9HBB4|ensembl:ENSP00000295408.4	"psi-mi:q5nhl4_fratt(display_long)|uniprotkb:mpl(gene name)|psi-mi:mpl(display_short)|uniprotkb:Murein peptide ligase(gene name synonym)|uniprotkb:""UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase""(gene name synonym)|uniprotkb:FTT_0438(locus name)"	psi-mi:mertk_human(display_long)|uniprotkb:MER(gene name synonym)|uniprotkb:Proto-oncogene c-Mer(gene name synonym)|uniprotkb:Receptor tyrosine kinase MerTK(gene name synonym)|uniprotkb:MERTK(gene name)|psi-mi:MERTK(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804920|imex:IM-13779-862	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005757(""UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase"")|refseq:YP_169478.1|go:""GO:0005524""(ATP binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0009254""(peptidoglycan turnover)|go:""GO:0051301""(cell division)|go:""GO:0071555""(cell wall organization)|go:""GO:0106418""(UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase activity)|refseq:WP_003020193.1|interpro:IPR036565|interpro:IPR036615|interpro:IPR050061"	"ensembl:ENSG00000153208.19(gene)|ensembl:ENST00000295408.9(transcript)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001779""(natural killer cell differentiation)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006909""(phagocytosis)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007399""(nervous system development)|go:""GO:0008288""(boss receptor activity)|go:""GO:0016477""(cell migration)|go:""GO:0030168""(platelet activation)|go:""GO:0032940""(secretion by cell)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0043235""(receptor complex)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0051250""(negative regulation of lymphocyte activation)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0060068""(vagina development)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:2000107""(negative regulation of leukocyte apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036179|interpro:IPR050122|mint:Q12866|rcsb pdb:2DBJ|rcsb pdb:2P0C|rcsb pdb:3BPR|rcsb pdb:3BRB|rcsb pdb:3TCP|rcsb pdb:4M3Q|rcsb pdb:4MH7|rcsb pdb:4MHA|rcsb pdb:5K0K|rcsb pdb:5K0X|rcsb pdb:5TC0|rcsb pdb:5TD2|rcsb pdb:5U6C|rcsb pdb:6MEP|rcsb pdb:7AAX|rcsb pdb:7AAY|rcsb pdb:7AAZ|rcsb pdb:7AB0|rcsb pdb:7AB1|rcsb pdb:7AB2|rcsb pdb:7AVX|rcsb pdb:7AVY|rcsb pdb:7AVZ|rcsb pdb:7AW0|rcsb pdb:7AW1|rcsb pdb:7AW2|rcsb pdb:7AW3|rcsb pdb:7AW4|rcsb pdb:7CQE|rcsb pdb:7DXL|rcsb pdb:7M5Z|rcsb pdb:7OAM|rcsb pdb:7OLS|rcsb pdb:7OLV|rcsb pdb:7OLX|rcsb pdb:7XHY|rcsb pdb:9BHI|rcsb pdb:9BHJ|rcsb pdb:9BHK|reactome:R-HSA-202733|refseq:NP_006334.2|efo:""Orphanet:791""|ensembl:ENSP00000295408.4|panther:PTHR24416(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6uME0/eIBas6qdPU6ajdbqJXUsY177416	rogid:d1TXRqQHZG+X91BEM32fecg/0bU9606	intact-crc:2724427660BB1F3B|rigid:t3Llu56JzyOM1XaUZtWrje5GZTI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NPJ6	uniprotkb:Q5NEC0	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648.2	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804950|imex:IM-13779-861	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146.15(gene)|ensembl:ENST00000258648.7(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016592""(mediator complex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070847""(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|panther:PTHR13208(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:05735C3E7B8579D6|rigid:73/lvFbautKk40BwCpimWrDBEQk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NG24	uniprotkb:O14770	intact:EBI-2803358|uniprotkb:A0A0G2RMN6	intact:EBI-2804934|uniprotkb:Q96KI5|uniprotkb:Q9NRS3|uniprotkb:Q9NRS1|uniprotkb:Q9NRS2|uniprotkb:Q96KI4|uniprotkb:A6NJI5|uniprotkb:A8MWD5|uniprotkb:B3KP98|uniprotkb:B3KPQ6|uniprotkb:Q96DI2|ensembl:ENSP00000453793.1	psi-mi:q5ng24_fratt(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:FTT_1035c(locus name)	psi-mi:meis2_human(display_long)|uniprotkb:MRG1(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym)|uniprotkb:MEIS2(gene name)|psi-mi:MEIS2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804943|imex:IM-13779-863	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028630|interpro:IPR007627(RNA polymerase sigma-70 region 2)|refseq:YP_170018.1|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016987""(sigma factor activity)|refseq:WP_003021146.1|interpro:IPR042189|interpro:IPR036388|interpro:IPR050239"	"ensembl:ENSG00000134138.22(gene)|ensembl:ENST00000561208.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001654""(eye development)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0007420""(brain development)|go:""GO:0008134""(transcription factor binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008542""(visual learning)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0009880""(embryonic pattern specification)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0031016""(pancreas development)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045638""(negative regulation of myeloid cell differentiation)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070848""(response to growth factor)|go:""GO:0110024""(positive regulation of cardiac muscle myoblast proliferation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|interpro:IPR050224|mint:O14770|rcsb pdb:3K2A|rcsb pdb:4XRM|rcsb pdb:5BNG|rcsb pdb:5EG0|refseq:NP_001207411.1|refseq:NP_002390.1|refseq:NP_733774.1|refseq:NP_733775.1|refseq:NP_733776.1|refseq:NP_733777.1|refseq:NP_758526.1|refseq:NP_758527.1|refseq:XP_016877694.1|dip:DIP-61027N|efo:""Orphanet:261190""|panther:PTHR11850(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:8d3IsZ3gHsN+yZIi+h+WLgKX8Tc177416	rogid:dzZaH/NCkNWqc4N6ZVa+i5Knqrg9606	intact-crc:558452B60B0CBB79|rigid:wymu0PgHqRkl2F0uFX7Cm9p/63Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHH0	uniprotkb:Q12866	intact:EBI-2801640|uniprotkb:A0A0G2RN01	intact:EBI-2804911|uniprotkb:Q9HBB4|ensembl:ENSP00000295408.4	psi-mi:q5nhh0_fratt(display_long)|uniprotkb:FTT_0484(locus name)	psi-mi:mertk_human(display_long)|uniprotkb:MER(gene name synonym)|uniprotkb:Proto-oncogene c-Mer(gene name synonym)|uniprotkb:Receptor tyrosine kinase MerTK(gene name synonym)|uniprotkb:MERTK(gene name)|psi-mi:MERTK(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804927|imex:IM-13779-860	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_169522.1|refseq:WP_003020297.1	"ensembl:ENSG00000153208.19(gene)|ensembl:ENST00000295408.9(transcript)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001779""(natural killer cell differentiation)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006909""(phagocytosis)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007399""(nervous system development)|go:""GO:0008288""(boss receptor activity)|go:""GO:0016477""(cell migration)|go:""GO:0030168""(platelet activation)|go:""GO:0032940""(secretion by cell)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0043235""(receptor complex)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0051250""(negative regulation of lymphocyte activation)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0060068""(vagina development)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:2000107""(negative regulation of leukocyte apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036179|interpro:IPR050122|mint:Q12866|rcsb pdb:2DBJ|rcsb pdb:2P0C|rcsb pdb:3BPR|rcsb pdb:3BRB|rcsb pdb:3TCP|rcsb pdb:4M3Q|rcsb pdb:4MH7|rcsb pdb:4MHA|rcsb pdb:5K0K|rcsb pdb:5K0X|rcsb pdb:5TC0|rcsb pdb:5TD2|rcsb pdb:5U6C|rcsb pdb:6MEP|rcsb pdb:7AAX|rcsb pdb:7AAY|rcsb pdb:7AAZ|rcsb pdb:7AB0|rcsb pdb:7AB1|rcsb pdb:7AB2|rcsb pdb:7AVX|rcsb pdb:7AVY|rcsb pdb:7AVZ|rcsb pdb:7AW0|rcsb pdb:7AW1|rcsb pdb:7AW2|rcsb pdb:7AW3|rcsb pdb:7AW4|rcsb pdb:7CQE|rcsb pdb:7DXL|rcsb pdb:7M5Z|rcsb pdb:7OAM|rcsb pdb:7OLS|rcsb pdb:7OLV|rcsb pdb:7OLX|rcsb pdb:7XHY|rcsb pdb:9BHI|rcsb pdb:9BHJ|rcsb pdb:9BHK|reactome:R-HSA-202733|refseq:NP_006334.2|efo:""Orphanet:791""|ensembl:ENSP00000295408.4|panther:PTHR24416(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:85+752TOqMA9Cs7A1Xauk1I1owE177416	rogid:d1TXRqQHZG+X91BEM32fecg/0bU9606	intact-crc:16E0427661C99123|rigid:U+PYa4aCyp7Chzqjkr8x12GvWvg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13503	uniprotkb:Q5NEC0	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892.3	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804975|imex:IM-13779-867	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR13381(orthology-group)|refseq:NP_004255.2|ensembl:ENSG00000152944.9(gene)|ensembl:ENST00000282892.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070847""(core mediator complex)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110|dip:DIP-31471N"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:2714B149702A13B2|rigid:xmxbVBUm2QroWvzOkER3etWOvgs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NXL9	uniprotkb:Q5NF50	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|ensembl:ENSP00000314505.5|ensembl:ENSP00000480469.1|uniprotkb:B4DR30|uniprotkb:B9DI77|intact:EBI-28972951	intact:EBI-2799423|uniprotkb:A0A0G2RN72	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:q5nf50_fratt(display_long)|uniprotkb:Exonuclease V subunit RecC(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecC(gene name synonym)|uniprotkb:recC(gene name)|psi-mi:recC(display_short)|uniprotkb:FTT_1397c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804982|imex:IM-13779-865	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111877.18(gene)|ensembl:ENST00000316316.10(transcript)|ensembl:ENST00000619706.5(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0006974""(DNA damage response)|go:""GO:0007292""(female gamete generation)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0032406""(MutLbeta complex binding)|go:""GO:0032407""(MutSalpha complex binding)|go:""GO:0032408""(MutSbeta complex binding)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0036298""(recombinational interstrand cross-link repair)|go:""GO:0042555""(MCM complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070716""(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:""GO:0071168""(protein localization to chromatin)|go:""GO:0097362""(MCM8-MCM9 complex)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:Q9NXL9|rcsb pdb:7DPD|rcsb pdb:7WI7|rcsb pdb:7YOX|rcsb pdb:8S91|rcsb pdb:8S92|rcsb pdb:8S94|refseq:NP_060166.2|refseq:NP_694987.1|efo:""Orphanet:444048""|panther:PTHR11630(orthology-group)"	"interpro:IPR006697(Exodeoxyribonuclease V, RecC subunit)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|refseq:YP_170342.1|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|refseq:WP_003022201.1|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR041500"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:dix8s5jOlPbCloD4EjJhnk5rYr4177416	intact-crc:7BEA228CDDAC380C|rigid:XW2mcAMyCMYWQj+AgcpsLXxlr0M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIL2	uniprotkb:Q9ULK4	intact:EBI-2804967|uniprotkb:A0A0G2RPB6	intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047.3|uniprotkb:B9TX55	psi-mi:q5nil2_fratt(display_long)|uniprotkb:rluC(gene name)|psi-mi:rluC(display_short)|uniprotkb:FTT_0055(locus name)	psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804964|imex:IM-13779-864	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020103|interpro:IPR006225(Pseudouridine synthase, RluD)|interpro:IPR006224(Pseudouridine synthase, conserved site)|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|refseq:YP_169130.1|go:""GO:0000455""(enzyme-directed rRNA pseudouridine synthesis)|go:""GO:0003723""(RNA binding)|go:""GO:0016829""(lyase activity)|go:""GO:0160141""(""23S rRNA pseudouridine(955/2504/2580) synthase activity"")|refseq:WP_003019697.1|interpro:IPR036986|interpro:IPR050188"	"ensembl:ENSG00000112282.18(gene)|ensembl:ENST00000368068.8(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006367""(transcription initiation at RNA polymerase II promoter)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070847""(core mediator complex)|go:""GO:2000409""(positive regulation of T cell extravasation)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|refseq:NP_001257450.1|refseq:NP_001257451.1|refseq:NP_004821.2|refseq:NP_057063.2|efo:""Orphanet:88616""|dip:DIP-31461N|ensembl:ENST00000354577.8|ensembl:ENSP00000346588.4|ensembl:ENST00000368053.8|ensembl:ENSP00000357032.4|ensembl:ENST00000368060.7|ensembl:ENSP00000357039.3|ensembl:ENSP00000357047.3|ensembl:ENST00000539158.1|ensembl:ENSP00000445072.1|panther:PTHR12691(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:p2QBWvIR0o9tQUJSUE3bkpqXfv0177416	rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606	intact-crc:973EDA611BB0B4E6|rigid:f4lvFNQsYB9tzoEQ/QZyJ3M2gLw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H204	uniprotkb:Q5NFJ2	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380.6	intact:EBI-2801973|uniprotkb:A0A0G2RP12	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	psi-mi:q5nfj2_fratt(display_long)|uniprotkb:FTT_1242(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804957|imex:IM-13779-866	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079481.2|panther:PTHR13512(orthology-group)|ensembl:ENSG00000118579.13(gene)|ensembl:ENST00000237380.12(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016020""(membrane)|go:""GO:0016592""(mediator complex)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0051151""(negative regulation of smooth muscle cell differentiation)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070847""(core mediator complex)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110"	refseq:YP_170200.1|refseq:WP_003021546.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	rogid:2TebkELetBwT7JBLunOX5Gxqzdk177416	intact-crc:24FF77A0AA2ADC81|rigid:qJrDNFxWUzFlEVBtSZxSms9yH7M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHR0	uniprotkb:Q9NR56	intact:EBI-2804868	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	psi-mi:glmu_fratt(display_long)|uniprotkb:FTT_0387(locus name)|uniprotkb:glmU(gene name)|psi-mi:glmU(display_short)	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805010|imex:IM-13779-868	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005882(UDP-N-acetylglucosamine pyrophosphorylase)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR018357|interpro:IPR011004(Trimeric LpxA-like)|refseq:YP_169432.1|interpro:IPR025877|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003977""(UDP-N-acetylglucosamine diphosphorylase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019134""(glucosamine-1-phosphate N-acetyltransferase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR029044|interpro:IPR038009|interpro:IPR050065|refseq:WP_003027098.1"	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:u55iLVubTfB1g8ht4JIk53ncUmQ177416	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	intact-crc:FE65C63E41EE4BF8|rigid:2hlLGyz2oyJeDtYqcsl/x+xEYq0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIJ3	uniprotkb:O60318	intact:EBI-2798422|uniprotkb:A0A0G2RM06	intact:EBI-308480|uniprotkb:Q2M3C1|uniprotkb:Q9UMT4|uniprotkb:C9JL56|uniprotkb:Q6PJP6|uniprotkb:Q9BSY5|ensembl:ENSP00000291688.1|ensembl:ENSP00000380820.1	psi-mi:q5nij3_fratt(display_long)|uniprotkb:sdhA(gene name)|psi-mi:sdhA(display_short)|uniprotkb:FTT_0074(locus name)	psi-mi:ganp_human(display_long)|uniprotkb:MCM3AP(gene name)|psi-mi:MCM3AP(display_short)|uniprotkb:GANP(gene name synonym)|uniprotkb:KIAA0572(gene name synonym)|uniprotkb:MAP80(gene name synonym)|uniprotkb:80 kDa MCM3-associated protein(gene name synonym)|uniprotkb:MCM3 acetylating protein(gene name synonym)|uniprotkb:MCM3 acetyltransferase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2804997|imex:IM-13779-869	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0008177""(""succinate dehydrogenase (quinone) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0009061""(anaerobic respiration)|go:""GO:0022900""(electron transport chain)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|refseq:YP_169149.1|interpro:IPR027477|refseq:WP_003019788.1|interpro:IPR036188|interpro:IPR037099|interpro:IPR030664"	"refseq:NP_003897.2|refseq:XP_005261262.1|refseq:XP_005261260.1|refseq:XP_005261261.1|dip:DIP-31696N|interpro:IPR031907|interpro:IPR031908|interpro:IPR031910|interpro:IPR034265|ensembl:ENSG00000160294.11(gene)|ensembl:ENST00000291688.6(transcript)|ensembl:ENST00000397708.1(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0010484""(histone H3 acetyltransferase activity)|go:""GO:0015031""(protein transport)|go:""GO:0016446""(somatic hypermutation of immunoglobulin genes)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0031965""(nuclear membrane)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0034728""(nucleosome organization)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042393""(histone binding)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0044615""(nuclear pore nuclear basket)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0070390""(transcription export complex 2)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR035979|interpro:IPR045107|mint:O60318|rcsb pdb:4DHX|panther:PTHR12436(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:sDR33MuGlwHfY9HuZdMhwuYSZI8177416	rogid:7WgKNrY4EPZGmfDj7es5SWEfTYM9606	intact-crc:2A68667710123DC5|rigid:XnrcB64Sdp40oLecHdZO0GqOwDM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27816	uniprotkb:Q5NF74	intact:EBI-715255|uniprotkb:Q59FT2|uniprotkb:Q68D74|uniprotkb:Q6ZUW9|uniprotkb:Q96NS9|uniprotkb:Q13082|uniprotkb:Q96A76|uniprotkb:Q86V26|ensembl:ENSP00000353375.6	intact:EBI-2796785|uniprotkb:A0A0G2RND4	psi-mi:map4_human(display_long)|uniprotkb:MAP4(gene name)|psi-mi:MAP4(display_short)	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805031|imex:IM-13779-873	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002366.2|refseq:NP_001127836.1|refseq:NP_112147.2|ensembl:ENSG00000047849.22(gene)|ensembl:ENST00000360240.10(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0005930""(axoneme)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030424""(axon)|go:""GO:0031175""(neuron projection development)|go:""GO:0043005""(neuron projection)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0051012""(microtubule sliding)|go:""GO:0051294""(establishment of spindle orientation)|go:""GO:0051301""(cell division)|go:""GO:0061523""(cilium disassembly)|go:""GO:0072686""(mitotic spindle)|go:""GO:0140778""(microtubule stabilizing activity)|go:""GO:1902856""(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027324|mint:P27816|panther:PTHR11501(orthology-group)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rBf82W3kFCo+2UklK5WHO3MWjV09606	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	intact-crc:724087B709F5C8EF|rigid:qjOR7JbL7sD+6IIfgxdkj3g6Xyk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27448	uniprotkb:Q5NGV3	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	intact:EBI-2797317	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	psi-mi:q5ngv3_fratt(display_long)|uniprotkb:FTT_0726c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805024|imex:IM-13779-870	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"go:""GO:0006629""(lipid metabolic process)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|interpro:IPR017946|refseq:YP_169739.1|interpro:IPR030395|refseq:WP_003020543.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	rogid:3e+5yrpF/Mx2IYeXH2egqOFVYbs177416	intact-crc:170F38B010890B89|rigid:73nG2G0QseBZ7mJCPGypvsVyO/Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27448	uniprotkb:Q5NHK6	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	intact:EBI-2798531|uniprotkb:A0A0G2RM87	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	psi-mi:q5nhk6_fratt(display_long)|uniprotkb:FTT_0448c(locus name)|uniprotkb:glnS(gene name)|psi-mi:glnS(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805017|imex:IM-13779-872	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"interpro:IPR020061|refseq:YP_169486.1|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004514(Glutaminyl-tRNA synthetase, class Ic)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020058|interpro:IPR020059|interpro:IPR020056|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|go:""GO:0004819""(glutamine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006425""(glutaminyl-tRNA aminoacylation)|refseq:WP_003020211.1|interpro:IPR050132|interpro:IPR049437"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	rogid:dgmtPrAewQIQt9hSyzijuiBx78A177416	intact-crc:52DBE7B011A00D6A|rigid:mYgplJKyzM8p8rAJZi7fj15iGxo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2805038	uniprotkb:Q5NIF9	-	intact:EBI-2799085|uniprotkb:A0A0G2RQ41	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	psi-mi:q5nif9_fratt(display_long)|uniprotkb:Phosphodeoxyribomutase(gene name synonym)|uniprotkb:deoB(gene name)|psi-mi:deoB(display_short)|uniprotkb:FTT_0113(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805042|imex:IM-13779-871	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR010045(Phosphopentomutase)|interpro:IPR006124(Metalloenzyme)|interpro:IPR024052|refseq:YP_169183.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006015""(5-phosphoribose 1-diphosphate biosynthetic process)|go:""GO:0006018""(2-deoxyribose 1-phosphate catabolic process)|go:""GO:0008973""(phosphopentomutase activity)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0043094""(metabolic compound salvage)|refseq:WP_003019856.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	rogid:A5Ci9aiQ72qwd1VqfoGwme/pcM4177416	intact-crc:BC0AED920D8A8F5C|rigid:otjEDjul5b+Fb9BNPygDKqUErNU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96QZ7	uniprotkb:Q5NEC0	intact:EBI-924464|uniprotkb:O00309|uniprotkb:O43863|uniprotkb:O75085|uniprotkb:Q96QZ8|uniprotkb:Q96QZ9|intact:EBI-1059162|uniprotkb:A8K188	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:magi1_human(display_long)|uniprotkb:MAGI1(gene name)|psi-mi:MAGI1(display_short)|uniprotkb:BAIAP1(gene name synonym)|uniprotkb:BAP1(gene name synonym)|uniprotkb:TNRC19(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 3(gene name synonym)|uniprotkb:WW domain-containing protein 3(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 19 protein(gene name synonym)|uniprotkb:AIP3(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805077|imex:IM-13779-878	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001028229.1|refseq:NP_004733.2|refseq:NP_056335.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR027417|refseq:XP_005265621.1|go:""GO:0001886""(endothelial cell morphogenesis)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0022409""(positive regulation of cell-cell adhesion)|go:""GO:0030054""(cell junction)|go:""GO:0042995""(cell projection)|go:""GO:0051393""(alpha-actinin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071944""(cell periphery)|rcsb pdb:1WBP|rcsb pdb:2KPK|rcsb pdb:2KPL|rcsb pdb:2Q9V|rcsb pdb:2R4H|rcsb pdb:2YSD|rcsb pdb:2YSE|rcsb pdb:2ZAJ|rcsb pdb:3BPU|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7P71|mint:Q96QZ7|interpro:IPR036020|interpro:IPR036034|panther:PTHR10316(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WN0iaCIXUObtJMGO7eRlQdaGDSk9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:1083026804ED9F9D|rigid:/8fhb+PrVobcvN+bCE7fy/FWE/E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2805038	uniprotkb:Q5NH91	-	intact:EBI-2804245|uniprotkb:A0A0G2RMJ8	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	psi-mi:q5nh91_fratt(display_long)|uniprotkb:sdaA(gene name)|psi-mi:sdaA(display_short)|uniprotkb:FTT_0577(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805049|imex:IM-13779-876	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"interpro:IPR004644(Iron-sulphur-dependent L-serine dehydratase single chain form)|interpro:IPR005130(Serine dehydratase alpha chain)|interpro:IPR005131(Serine dehydratase beta chain)|refseq:YP_169601.1|go:""GO:0003941""(L-serine ammonia-lyase activity)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR029009|refseq:WP_003019268.1|interpro:IPR051318"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	rogid:rAJJN6zltZpSciqSe5iWZMw1tLg177416	intact-crc:A6589C920F7CF5E5|rigid:VPY8N/CC5a6y38X9OT4KqIxzr0g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2805038	uniprotkb:Q5NEC0	-	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805063|imex:IM-13779-877	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:E821A1920F30A778|rigid:+o8HQvZ9Vxp5taYvYWerGQB0bIw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHE7	uniprotkb:Q96QZ7	intact:EBI-2797375	intact:EBI-924464|uniprotkb:O00309|uniprotkb:O43863|uniprotkb:O75085|uniprotkb:Q96QZ8|uniprotkb:Q96QZ9|intact:EBI-1059162|uniprotkb:A8K188	psi-mi:q5nhe7_fratt(display_long)|uniprotkb:gyrB(gene name)|psi-mi:gyrB(display_short)|uniprotkb:FTT_0510(locus name)	psi-mi:magi1_human(display_long)|uniprotkb:MAGI1(gene name)|psi-mi:MAGI1(display_short)|uniprotkb:BAIAP1(gene name synonym)|uniprotkb:BAP1(gene name synonym)|uniprotkb:TNRC19(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 3(gene name synonym)|uniprotkb:WW domain-containing protein 3(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 19 protein(gene name synonym)|uniprotkb:AIP3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805070|imex:IM-13779-875	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006265""(DNA topological change)|go:""GO:0034335""(DNA negative supercoiling activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR034160|refseq:YP_169545.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011557(DNA gyrase, subunit B)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR006171(TOPRIM)|interpro:IPR036890|interpro:IPR049353|interpro:IPR041423|interpro:IPR000565(DNA topoisomerase, type IIA, subunit B)"	"refseq:NP_001028229.1|refseq:NP_004733.2|refseq:NP_056335.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR027417|refseq:XP_005265621.1|go:""GO:0001886""(endothelial cell morphogenesis)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0022409""(positive regulation of cell-cell adhesion)|go:""GO:0030054""(cell junction)|go:""GO:0042995""(cell projection)|go:""GO:0051393""(alpha-actinin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071944""(cell periphery)|rcsb pdb:1WBP|rcsb pdb:2KPK|rcsb pdb:2KPL|rcsb pdb:2Q9V|rcsb pdb:2R4H|rcsb pdb:2YSD|rcsb pdb:2YSE|rcsb pdb:2ZAJ|rcsb pdb:3BPU|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7P71|mint:Q96QZ7|interpro:IPR036020|interpro:IPR036034|panther:PTHR10316(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ThkiaCkVSV3ry1m8DcM5w6kTEVs177416	rogid:WN0iaCIXUObtJMGO7eRlQdaGDSk9606	intact-crc:6E9888061EE9AEB3|rigid:fLJ8FCZwP+9oFCLNie3C6eWTe/k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2805038	uniprotkb:Q5NGC3	-	intact:EBI-2799367	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	psi-mi:rlmkl_fratt(display_long)|uniprotkb:FTT_0923(locus name)|uniprotkb:rlmL(gene name)|psi-mi:rlmL(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805056|imex:IM-13779-874	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"interpro:IPR029063|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR000241(Putative RNA methylase)|interpro:IPR017244(S-adenosyl-L-dependent RNA methyltransferase, bacteria, predicted)|interpro:IPR019614|interpro:IPR004114(THUMP)|refseq:YP_169919.1|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0052915""(""23S rRNA (guanine(2445)-N(2))-methyltransferase activity"")|go:""GO:0070043""(""rRNA (guanine-N7-)-methyltransferase activity"")|refseq:WP_003020954.1|interpro:IPR053943|interpro:IPR054170"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	rogid:sWSyt1AaFWM8rwCbDjRuj4j1vDM177416	intact-crc:BA9B43920FD5A64A|rigid:YIu7jNeG+u+naF3BjX67Q3CWRT0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NII1	uniprotkb:Q8WXG6	intact:EBI-2797156|uniprotkb:A0A0G2RN00	intact:EBI-310528|ensembl:ENSP00000310933.4|uniprotkb:O15293|intact:EBI-728168|uniprotkb:D3DQR4|uniprotkb:Q15732|uniprotkb:Q15741|uniprotkb:Q8IWD7|uniprotkb:Q8WXG3|uniprotkb:Q8WXG4|uniprotkb:Q8WXG5|uniprotkb:Q8WZ63|uniprotkb:O15065|uniprotkb:A8K8S7|uniprotkb:B5MEE5	psi-mi:q5nii1_fratt(display_long)|uniprotkb:acnA(gene name)|psi-mi:acnA(display_short)|uniprotkb:FTT_0087(locus name)	psi-mi:madd_human(display_long)|uniprotkb:MADD(gene name)|psi-mi:MADD(display_short)|uniprotkb:DENN(gene name synonym)|uniprotkb:IG20(gene name synonym)|uniprotkb:KIAA0358(gene name synonym)|uniprotkb:Differentially expressed in normal and neoplastic cells(gene name synonym)|uniprotkb:Insulinoma glucagonoma clone 20(gene name synonym)|uniprotkb:Rab3 GDP/GTP exchange factor(gene name synonym)|uniprotkb:Rab3 GDP/GTP exchange protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805104|imex:IM-13779-880	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR044137|refseq:YP_169161.1|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR018136|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|refseq:WP_003019815.1|interpro:IPR036008"	"ensembl:ENSG00000110514.20(gene)|ensembl:ENST00000311027.9(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005123""(death receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0030424""(axon)|go:""GO:0032483""(regulation of Rab protein signal transduction)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:2001236""(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR037516|interpro:IPR039980|interpro:IPR043153|mint:Q8WXG6|reactome:R-HSA-5357905|reactome:R-HSA-8876198|refseq:NP_001129415.1|refseq:NP_001129416.1|refseq:NP_003673.3|refseq:NP_569826.2|refseq:NP_569827.2|refseq:NP_569828.2|refseq:NP_569829.2|refseq:NP_569830.2|refseq:NP_569831.1|refseq:NP_569832.2|refseq:XP_005253246.1|refseq:XP_005253253.1|refseq:XP_005253256.1|refseq:XP_005253258.1|refseq:XP_005253260.1|refseq:XP_005253261.1|refseq:XP_005253262.1|efo:""Orphanet:686495""|efo:""Orphanet:528084""|panther:PTHR13008(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FGVUBUKOHsDquKU0LqPkXCpRg+o177416	rogid:+YF66uj9WWG+hZ6fvrmXfelsQZs9606	intact-crc:F1AF4DA3B7A6ECEF|rigid:hdKZ8k2YPBV6weIYI7smBJ0mA2c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60664	uniprotkb:Q5NGP5	intact:EBI-725795|uniprotkb:Q53G77|uniprotkb:Q9BS03|uniprotkb:Q9UBD7|uniprotkb:Q9UP92|uniprotkb:A8K4Y9|uniprotkb:K7EQF4|intact:EBI-11103673|ensembl:ENSP00000221957.3	intact:EBI-2805111|uniprotkb:A0A0G2RNZ5	psi-mi:plin3_human(display_long)|uniprotkb:Cargo selection protein TIP47(gene name synonym)|uniprotkb:47 kDa mannose 6-phosphate receptor-binding protein(gene name synonym)|uniprotkb:Placental protein 17(gene name synonym)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short)|uniprotkb:TIP47(gene name synonym)|uniprotkb:M6PRBP1(gene name synonym)|uniprotkb:Mannose-6-phosphate receptor-binding protein 1(gene name synonym)	psi-mi:q5ngp5_fratt(display_long)|uniprotkb:FTT_0790(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805114|imex:IM-13779-882	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001157666.1|refseq:NP_001157661.1|refseq:NP_005808.3|ensembl:ENSG00000105355.9(gene)|ensembl:ENST00000221957.9(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0010008""(endosome membrane)|go:""GO:0010890""(positive regulation of triglyceride storage)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019915""(lipid storage)|go:""GO:0030133""(transport vesicle)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0045296""(cadherin binding)|go:""GO:1905691""(lipid droplet disassembly)|interpro:IPR004279(Perilipin)|mint:O60664|reactome:R-HSA-163560|reactome:R-HSA-6811440|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9706019|panther:PTHR14024(orthology-group)"	"interpro:IPR003362(Bacterial sugar transferase)|interpro:IPR017475(Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase)|refseq:YP_169797.1|go:""GO:0016020""(membrane)|go:""GO:0016780""(phosphotransferase activity, for other substituted phosphate groups)|refseq:WP_003020689.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:U+skqZ/oQtQscaEvfdh+AVnCCKA9606	rogid:+7pQBY2ppc01gaMXgnd1ZTQVgjs177416	intact-crc:8E4AE0DF7354B8D5|rigid:uEUeNsFIGh2s4rxXNJn4LtgnGDM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGZ2	uniprotkb:Q9UNF1	intact:EBI-2799396	intact:EBI-725832|uniprotkb:O76058|uniprotkb:Q5BJF3|uniprotkb:Q8NAL6|uniprotkb:Q9H218|uniprotkb:Q9P0U9|uniprotkb:A6NMX0|uniprotkb:Q9UM52|ensembl:ENSP00000218439.4|ensembl:ENSP00000364193.2|ensembl:ENSP00000364198.1|ensembl:ENSP00000364209.1|ensembl:ENSP00000379526.1|intact:EBI-21354087	"psi-mi:q5ngz2_fratt(display_long)|uniprotkb:sthA(gene name)|psi-mi:sthA(display_short)|uniprotkb:""NAD(P)(+) transhydrogenase [B-specific]""(gene name synonym)|uniprotkb:FTT_0684c(locus name)"	psi-mi:magd2_human(display_long)|uniprotkb:MAGE-D2 antigen(gene name synonym)|uniprotkb:Breast cancer-associated gene 1 protein(gene name synonym)|uniprotkb:11B6(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated protein JCL-1(gene name synonym)|uniprotkb:MAGED2(gene name)|psi-mi:MAGED2(display_short)|uniprotkb:BCG1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805084|imex:IM-13779-879	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|refseq:YP_169700.1|go:""GO:0003957""(""NAD(P)+ transhydrogenase (Si-specific) activity"")|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR036188|interpro:IPR050151"	"efo:""Orphanet:570371""|dip:DIP-50722N|ensembl:ENSG00000102316.17(gene)|ensembl:ENST00000218439.8(transcript)|ensembl:ENST00000375053.6(transcript)|ensembl:ENST00000375058.5(transcript)|ensembl:ENST00000375068.6(transcript)|ensembl:ENST00000396224.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0007565""(female pregnancy)|go:""GO:0016020""(membrane)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0070294""(renal sodium ion absorption)|interpro:IPR002190(MAGE protein)|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9UNF1|reactome:R-HSA-114608|refseq:NP_055414.2|refseq:NP_803182.1|refseq:NP_957516.1|panther:PTHR11736(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:FVMwWTRsRhqkp8VA6v1GvkbWerE177416	rogid:fXavezmKy58aGuVgzvDYjwNw3B89606	intact-crc:F7759CADF9CAD535|rigid:GplxejHaUGoeZyOeCAwfeHoSS7k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIL8	uniprotkb:O75444	intact:EBI-2797707|uniprotkb:A0A0G2RN29	intact:EBI-2805091|uniprotkb:Q66I47|uniprotkb:Q9UP93|ensembl:ENSP00000377019.1	psi-mi:q5nil8_fratt(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:FTT_0049(locus name)	psi-mi:maf_human(display_long)|uniprotkb:Proto-oncogene c-Maf(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog(gene name synonym)|uniprotkb:MAF(gene name)|psi-mi:MAF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805097|imex:IM-13779-881	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000166""(nucleotide binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|refseq:YP_169124.1|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010214(Transcription termination factor NusA, C-terminal duplication)|interpro:IPR010213(Transcription termination factor NusA)|interpro:IPR025249|interpro:IPR030842|refseq:WP_003019733.1|interpro:IPR036555"	"ensembl:ENSG00000178573.7(gene)|ensembl:ENST00000393350.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030219""(megakaryocyte differentiation)|go:""GO:0032330""(regulation of chondrocyte differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0048839""(inner ear development)|go:""GO:0070306""(lens fiber cell differentiation)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874|interpro:IPR046347|reactome:R-HSA-8940973|refseq:NP_001026974.1|refseq:NP_005351.2|efo:""Orphanet:1272""|efo:""Orphanet:1377""|efo:""Orphanet:98984""|efo:""Orphanet:98989""|panther:PTHR10129(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h3B/JHGk+VSXL6iylODRYTPeDAc177416	rogid:/LSZua5O9ik8/I6DayUfyiVM5Ms9606	intact-crc:68CC5A64EE205AAB|rigid:7YOCRP/iH6R+4aDvpuH2V2h8o80	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV7	uniprotkb:Q92918	intact:EBI-2796192	intact:EBI-881|intact:EBI-28975476|ensembl:ENSP00000465039.1	psi-mi:katg_fratt(display_long)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:FTT_0721c(locus name)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)	psi-mi:m4k1_human(display_long)|uniprotkb:HPK1(gene name synonym)|uniprotkb:MAP4K1(gene name)|psi-mi:MAP4K1(display_short)|uniprotkb:MAPK/ERK kinase kinase kinase 1(gene name synonym)|uniprotkb:Hematopoietic progenitor kinase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805121|imex:IM-13779-883	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169735.1|interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|refseq:WP_003020536.1|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)"	"refseq:NP_009112.1|refseq:NP_001036065.1|dip:DIP-31019N|panther:PTHR48012(orthology-group)|ensembl:ENSG00000104814.13(gene)|ensembl:ENST00000591517.5(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007254""(JNK cascade)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008349""(MAP kinase kinase kinase kinase activity)|go:""GO:0016020""(membrane)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1904628""(cellular response to phorbol 13-acetate 12-myristate)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR021160|interpro:IPR050629|mint:Q92918|rcsb pdb:6CQD|rcsb pdb:6CQE|rcsb pdb:6CQF|rcsb pdb:6NFY|rcsb pdb:6NFZ|rcsb pdb:6NG0|rcsb pdb:7KAC|rcsb pdb:7L24|rcsb pdb:7L25|rcsb pdb:7L26|rcsb pdb:7M0K|rcsb pdb:7M0L|rcsb pdb:7M0M|rcsb pdb:7R9L|rcsb pdb:7R9N|rcsb pdb:7R9P|rcsb pdb:7R9T|rcsb pdb:7SIU|rcsb pdb:8CDW|rcsb pdb:8CIJ|rcsb pdb:8EEC|rcsb pdb:8FH4|rcsb pdb:8FJZ|rcsb pdb:8FKO|rcsb pdb:8PAR|rcsb pdb:8PAS|rcsb pdb:8PAU|rcsb pdb:8XN7|rcsb pdb:9BI8|rcsb pdb:9BIK|rcsb pdb:9BJ1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UVLspYdPWJwb7VPBG0xNq1Pp2KQ177416	rogid:XAnNUBaT7pFyJMbz5gbC1ahCono9606	intact-crc:28B53DCDA6240684|rigid:gi06/W4FWfLfNOHekQD6+W8JEJY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H2W1	uniprotkb:Q5NGR8	intact:EBI-1266965|uniprotkb:F8W9K1|uniprotkb:Q8TBV7|uniprotkb:Q8TEZ4|uniprotkb:Q8TEZ5|uniprotkb:Q96PG6|uniprotkb:Q9H2L1|uniprotkb:Q9H2N3|uniprotkb:Q9H3V1|uniprotkb:Q9HC76|uniprotkb:A8K755|uniprotkb:Q7Z4E8|ensembl:ENSP00000436979.1	intact:EBI-2804477|uniprotkb:A0A0G2RNZ4	psi-mi:m4a6a_human(display_long)|uniprotkb:MS4A6A(gene name)|psi-mi:MS4A6A(display_short)|uniprotkb:4SPAN3(gene name synonym)|uniprotkb:CD20L3(gene name synonym)|uniprotkb:MS4A6(gene name synonym)|uniprotkb:CDA01(orf name)|uniprotkb:Four-span transmembrane protein 3(gene name synonym)|uniprotkb:CD20 antigen-like 3(gene name synonym)|uniprotkb:MSTP090(orf name)	psi-mi:q5ngr8_fratt(display_long)|uniprotkb:glyS(gene name)|psi-mi:glyS(display_short)|uniprotkb:Glycyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:FTT_0764(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805128|imex:IM-13779-885	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_071744.2|refseq:NP_690590.1|refseq:NP_690591.1|refseq:NP_001234928.1|ensembl:ENSG00000110077.16(gene)|ensembl:ENST00000530839.6(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|panther:PTHR23320(orthology-group)"	"interpro:IPR008909(DALR anticodon binding)|interpro:IPR006194(Glycyl-tRNA synthetase, class II, heterodimeric)|interpro:IPR015944(Glycyl-tRNA synthetase, class IIc, beta subunit)|refseq:YP_169774.1|go:""GO:0004814""(arginine-tRNA ligase activity)|go:""GO:0004820""(glycine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006420""(arginyl-tRNA aminoacylation)|go:""GO:0006426""(glycyl-tRNA aminoacylation)|refseq:WP_003020626.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:grulmeEQHMF87IF9Ln1V6UsDx7c9606	rogid:/WGBKDHNu5yRvWij90pXYwDMp0w177416	intact-crc:28237216AD8A9104|rigid:8A7lZtnA2FQLGLD1mv/wxAJxSo8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H2W1	uniprotkb:Q5NFZ8	intact:EBI-1266965|uniprotkb:F8W9K1|uniprotkb:Q8TBV7|uniprotkb:Q8TEZ4|uniprotkb:Q8TEZ5|uniprotkb:Q96PG6|uniprotkb:Q9H2L1|uniprotkb:Q9H2N3|uniprotkb:Q9H3V1|uniprotkb:Q9HC76|uniprotkb:A8K755|uniprotkb:Q7Z4E8|ensembl:ENSP00000436979.1	intact:EBI-2805138	psi-mi:m4a6a_human(display_long)|uniprotkb:MS4A6A(gene name)|psi-mi:MS4A6A(display_short)|uniprotkb:4SPAN3(gene name synonym)|uniprotkb:CD20L3(gene name synonym)|uniprotkb:MS4A6(gene name synonym)|uniprotkb:CDA01(orf name)|uniprotkb:Four-span transmembrane protein 3(gene name synonym)|uniprotkb:CD20 antigen-like 3(gene name synonym)|uniprotkb:MSTP090(orf name)	psi-mi:hem6_fratt(display_long)|uniprotkb:FTT_1063(locus name)|uniprotkb:hemF(gene name)|psi-mi:hemF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805135|imex:IM-13779-884	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_071744.2|refseq:NP_690590.1|refseq:NP_690591.1|refseq:NP_001234928.1|ensembl:ENSG00000110077.16(gene)|ensembl:ENST00000530839.6(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|panther:PTHR23320(orthology-group)"	"interpro:IPR001260(Coproporphyrinogen III oxidase)|interpro:IPR018375|refseq:YP_170044.1|go:""GO:0004109""(coproporphyrinogen oxidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_003023689.1|interpro:IPR036406"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:grulmeEQHMF87IF9Ln1V6UsDx7c9606	rogid:s8RqtN5Fryox8DtHprnNj7HHFvU177416	intact-crc:03760316AD8876A3|rigid:PkV8g07e1BCbdjEDPubyB+17TQo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHN7	uniprotkb:Q02978	intact:EBI-2802363|uniprotkb:A0A0G2RLZ9	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|uniprotkb:F5GY65|ensembl:ENSP00000225665.7	psi-mi:q5nhn7_fratt(display_long)|uniprotkb:gcvP2(gene name)|psi-mi:gcvP2(display_short)|uniprotkb:FTT_0410(locus name)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805146|imex:IM-13779-886	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020581|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:YP_169455.1|refseq:WP_011242235.1|go:""GO:0004375""(""glycine dehydrogenase (decarboxylating) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0016594""(glycine binding)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR049315|interpro:IPR049316"	"efo:""Orphanet:29072""|ensembl:ENSG00000108528.14(gene)|ensembl:ENST00000225665.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006869""(lipid transport)|go:""GO:0015116""(sulfate transmembrane transporter activity)|go:""GO:0015117""(thiosulfate transmembrane transporter activity)|go:""GO:0015131""(oxaloacetate transmembrane transporter activity)|go:""GO:0015140""(malate transmembrane transporter activity)|go:""GO:0015141""(succinate transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015367""(""oxoglutarate:malate antiporter activity"")|go:""GO:0015709""(thiosulfate transport)|go:""GO:0015729""(oxaloacetate transport)|go:""GO:0035435""(phosphate ion transmembrane transport)|go:""GO:0043490""(malate-aspartate shuttle)|go:""GO:0071422""(succinate transmembrane transport)|go:""GO:0071423""(malate transmembrane transport)|go:""GO:1902358""(sulfate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR050391|mint:Q02978|reactome:R-HSA-428643|reactome:R-HSA-9856872|refseq:NP_003553.2|panther:PTHR45618(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PrvVzFJYuRfdefUo4kpPUAO8pgg177416	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	intact-crc:6E2F4F57D9660B35|rigid:X5H9ex/Td5Kk7oBnFfpxSY5fnFQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI40	uniprotkb:O75427	intact:EBI-2796048	intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689.6	psi-mi:q5ni40_fratt(display_long)|uniprotkb:ppdK(gene name)|psi-mi:ppdK(display_short)|uniprotkb:FTT_0250(locus name)	psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805169|imex:IM-13779-889	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169302.1|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR018274|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR023151|interpro:IPR002192(Pyruvate phosphate dikinase, PEP/pyruvate-binding)|interpro:IPR010121(Pyruvate, phosphate dikinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR040442|interpro:IPR036637|go:""GO:0005524""(ATP binding)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0050242""(pyruvate, phosphate dikinase activity)"	"refseq:NP_002310.2|ensembl:ENSG00000077454.17(gene)|ensembl:ENST00000310300.11(transcript)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0007399""(nervous system development)|go:""GO:0016605""(PML body)|go:""GO:0034123""(positive regulation of toll-like receptor signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872|interpro:IPR050216|mint:O75427|refseq:NP_001276863.1|panther:PTHR16083(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lPu2TgwGa8adgnlyO6g7UzHr7Ns177416	rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606	intact-crc:504DA0E5122EE937|rigid:MyV0yFwMYZfDiW94lG+LEzU518g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGF1	uniprotkb:Q96CN5	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	intact:EBI-2805176|ensembl:ENSP00000306760.3	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	psi-mi:lrc45_human(display_long)|uniprotkb:LRRC45(gene name)|psi-mi:LRRC45(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805187|imex:IM-13779-890	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"refseq:NP_659436.1|ensembl:ENSG00000169683.8(gene)|ensembl:ENST00000306688.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR052116|mint:Q96CN5|dip:DIP-29482N|panther:PTHR23170(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	crc64:27F5D210721459FB	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	rogid:cuIAlpH4zLJ1La+TtOc2x4c2dMI9606	intact-crc:F38977E78BB48C1D|rigid:OhYjliu0Jjn+hynfJ7MrAv1sszw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96CN5	uniprotkb:Q5NIA8	intact:EBI-2805176|ensembl:ENSP00000306760.3	intact:EBI-2800376	psi-mi:lrc45_human(display_long)|uniprotkb:LRRC45(gene name)|psi-mi:LRRC45(display_short)	psi-mi:rf1_fratt(display_long)|uniprotkb:FTT_0168(locus name)|uniprotkb:prfA(gene name)|psi-mi:prfA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805180|imex:IM-13779-888	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_659436.1|ensembl:ENSG00000169683.8(gene)|ensembl:ENST00000306688.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR052116|mint:Q96CN5|dip:DIP-29482N|panther:PTHR23170(orthology-group)"	"interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004373(Peptide chain release factor 1)|refseq:YP_169234.1|go:""GO:0005737""(cytoplasm)|go:""GO:0016149""(translation release factor activity, codon specific)|refseq:WP_003019960.1|interpro:IPR050057|interpro:IPR045853"	"psi-mi:""MI:0469""(intact)"	crc64:27F5D210721459FB	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:cuIAlpH4zLJ1La+TtOc2x4c2dMI9606	rogid:6lZUlvLNR06AfQiCbfXKwNEmHoE177416	intact-crc:ACFAD9E7890E1D7E|rigid:CLd/AA8tV2PL4ixwwi80/wmfo8s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HBG7	uniprotkb:Q5NEC0	intact:EBI-2805156|uniprotkb:Q14775|uniprotkb:Q5VYI3|uniprotkb:Q9H4N5|uniprotkb:Q9NQ24|uniprotkb:A8K7N3|uniprotkb:Q6P2J4|ensembl:ENSP00000263285.5	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:ly9_human(display_long)|uniprotkb:Cell surface molecule Ly-9(gene name synonym)|uniprotkb:Lymphocyte antigen 9(gene name synonym)|uniprotkb:LY9(gene name)|psi-mi:LY9(display_short)|uniprotkb:SLAM family member 3(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule 3(gene name synonym)|uniprotkb:CDABP0070(orf name)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805153|imex:IM-13779-887	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002339.2|refseq:NP_001028839.1|refseq:NP_001248385.1|ensembl:ENSG00000122224.19(gene)|ensembl:ENST00000263285.11(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0042110""(T cell activation)|go:""GO:0045087""(innate immune response)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015631(Signaling lymphocyte activation molecule)|interpro:IPR036179|panther:PTHR12080(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:e+nqSQ98Em8oI0o3T7NiyffqoGI9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:F56FF67E23D260EA|rigid:3C/pRHKMmkQUKfcO4iCEzW3IpKE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20700	uniprotkb:Q5NFX8	intact:EBI-968218|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6|ensembl:ENSP00000261366.5	intact:EBI-2805211	psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym)	psi-mi:trho_fratt(display_long)|uniprotkb:trhO(gene name)|psi-mi:trhO(display_short)|uniprotkb:tRNA hydroxylation protein O(gene name synonym)|uniprotkb:FTT_1085(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805214|imex:IM-13779-892	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2514""|efo:""Orphanet:99027""|dip:DIP-34897N|ensembl:ENSG00000113368.12(gene)|ensembl:ENST00000261366.10(transcript)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043274""(phospholipase binding)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|rcsb pdb:3UMN|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:5BNW|rcsb pdb:5VVX|rcsb pdb:7DTG|reactome:R-HSA-1221632|reactome:R-HSA-2559584|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|panther:PTHR45721(orthology-group)"	"interpro:IPR001763(Rhodanese-like)|interpro:IPR020936|refseq:YP_170064.1|go:""GO:0006400""(tRNA modification)|go:""GO:0016705""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|interpro:IPR040503|interpro:IPR036873"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606	rogid:z6sdoiU+Hyn6Oovg5PW6TYh2RIc177416	intact-crc:E6D0AA01895C1F82|rigid:xUUsGR5s7BpGgf5258FAHPQzCd0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGW8	uniprotkb:O60711	intact:EBI-2803320	intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512.2	psi-mi:eno_fratt(display_long)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:FTT_0709(locus name)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)	psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805204|imex:IM-13779-893	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000941(Enolase)|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|refseq:YP_169724.1|go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006096""(glycolytic process)|go:""GO:0009986""(cell surface)|interpro:IPR029017|refseq:WP_003020514.1|interpro:IPR036849"	"refseq:NP_001137467.1|refseq:NP_004802.1|refseq:NP_001294880.1|ensembl:ENSG00000110031.13(gene)|ensembl:ENST00000395074.7(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042995""(cell projection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|panther:PTHR24216(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qlcpktC4i/OVSrB7dBccdJhHX2Y177416	rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606	intact-crc:1363BFC1EBF99C13|rigid:lphQE4gbGcO2cAsaRLwQyyzaX2M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20700	uniprotkb:Q5NGF6	intact:EBI-968218|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6|ensembl:ENSP00000261366.5	intact:EBI-2798182|uniprotkb:A0A0G2RN31	psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym)	psi-mi:q5ngf6_fratt(display_long)|uniprotkb:FTT_0889c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805221|imex:IM-13779-894	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2514""|efo:""Orphanet:99027""|dip:DIP-34897N|ensembl:ENSG00000113368.12(gene)|ensembl:ENST00000261366.10(transcript)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043274""(phospholipase binding)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|rcsb pdb:3UMN|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:5BNW|rcsb pdb:5VVX|rcsb pdb:7DTG|reactome:R-HSA-1221632|reactome:R-HSA-2559584|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|panther:PTHR45721(orthology-group)"	"go:""GO:0016020""(membrane)|interpro:IPR055160|interpro:IPR012902(Prepilin-type cleavage/methylation, N-terminal)|refseq:YP_169886.1|rcsb pdb:3SOJ|refseq:WP_003020879.1|interpro:IPR045584|interpro:IPR050470"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606	rogid:j8Bn0IlLtg5yjAogbk3Of9TM0do177416	intact-crc:FBB3DB018A77050D|rigid:zEMllLmnsdOibuofgfgs6Bhbm1k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NER8	uniprotkb:Q96CN5	intact:EBI-2805194|uniprotkb:A0A0G2RMW8	intact:EBI-2805176|ensembl:ENSP00000306760.3	psi-mi:q5ner8_fratt(display_long)|uniprotkb:FTT_1550(locus name)	psi-mi:lrc45_human(display_long)|uniprotkb:LRRC45(gene name)|psi-mi:LRRC45(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805197|imex:IM-13779-891	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_170474.1|interpro:IPR024409|refseq:WP_003022440.1	"refseq:NP_659436.1|ensembl:ENSG00000169683.8(gene)|ensembl:ENST00000306688.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR052116|mint:Q96CN5|dip:DIP-29482N|panther:PTHR23170(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	crc64:27F5D210721459FB	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:hp7l11NqYbF9p9VX01HSwUFqonI177416	rogid:cuIAlpH4zLJ1La+TtOc2x4c2dMI9606	intact-crc:B9E795E7890B341C|rigid:vfp0ROENfsfRzs9qkXBRcHd1BrQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NHJ6	uniprotkb:Q4VP87	intact:EBI-2805248|uniprotkb:A8MVL8|uniprotkb:Q8N1C7|uniprotkb:O15468|uniprotkb:O75021|uniprotkb:Q6FGQ9|uniprotkb:Q8NHL5|ensembl:ENSP00000375616.1|ensembl:ENSP00000479829.1	intact:EBI-2796861	psi-mi:lirb4_human(display_long)|uniprotkb:ILT3(gene name synonym)|uniprotkb:LIR5(gene name synonym)|uniprotkb:CD85 antigen-like family member K(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 3(gene name synonym)|uniprotkb:Leukocyte immunoglobulin-like receptor 5(gene name synonym)|uniprotkb:Monocyte inhibitory receptor HM18(gene name synonym)|uniprotkb:LILRB4(gene name)|psi-mi:LILRB4(display_short)	psi-mi:q4vp87_fratl(display_long)|uniprotkb:FTT0445(orf name)|uniprotkb:uup(gene name)|psi-mi:uup(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805245|imex:IM-13779-897	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001265355.2|refseq:NP_001265356.2|refseq:NP_001265357.2|refseq:NP_001265358.2|refseq:NP_001265359.2|ensembl:ENSG00000186818.13(gene)|ensembl:ENSG00000275730.4(gene)|ensembl:ENST00000391736.5(transcript)|ensembl:ENST00000612454.4(transcript)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002507""(tolerance induction)|go:""GO:0002669""(positive regulation of T cell anergy)|go:""GO:0002725""(negative regulation of T cell cytokine production)|go:""GO:0002764""(immune response-regulating signaling pathway)|go:""GO:0002774""(Fc receptor mediated inhibitory signaling pathway)|go:""GO:0005886""(plasma membrane)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030293""(transmembrane receptor protein tyrosine kinase inhibitor activity)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0031623""(receptor internalization)|go:""GO:0032396""(inhibitory MHC class I receptor activity)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032693""(negative regulation of interleukin-10 production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032714""(negative regulation of interleukin-5 production)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043378""(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0045584""(negative regulation of cytotoxic T cell differentiation)|go:""GO:0045591""(positive regulation of regulatory T cell differentiation)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0061099""(negative regulation of protein tyrosine kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071659""(negative regulation of IP-10 production)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1900016""(negative regulation of cytokine production involved in inflammatory response)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:2000272""(negative regulation of signaling receptor activity)|go:""GO:2000524""(negative regulation of T cell costimulation)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050412|rcsb pdb:3P2T|rcsb pdb:6K7O|reactome:R-HSA-198933|panther:PTHR11738(orthology-group)"	"go:""GO:0005524""(ATP binding)|interpro:IPR027417|interpro:IPR032781|interpro:IPR051309"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GC8ymLbHSWFCosuiUOuJc4igRYM9606	rogid:+Qbmzj8eW72wb4LBUxcHkhpPQRE119856	intact-crc:40985878D03A5113|rigid:lfcoL/hMCAKDjb/Wr/fifORY/5s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13136	uniprotkb:Q5NF74	intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|ensembl:ENSP00000253925.7|ensembl:ENSP00000500898.2|intact:EBI-28983934	intact:EBI-2796785|uniprotkb:A0A0G2RND4	psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym)	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805278|imex:IM-13779-898	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003617.1|refseq:NP_803172.1|interpro:IPR037621|ensembl:ENSG00000131626.19(gene)|ensembl:ENSG00000288198.2(gene)|ensembl:ENST00000253925.12(transcript)|ensembl:ENST00000672559.2(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0030424""(axon)|go:""GO:0032991""(protein-containing complex)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050808""(synapse organization)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0097444""(spine apparatus)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR037620|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|panther:PTHR12587(orthology-group)|ensembl:ENSP00000253925.7|ensembl:ENST00000389547.7|ensembl:ENSP00000374198.3|ensembl:ENSP00000500898.2|ensembl:ENST00000672873.2|ensembl:ENSP00000500481.2"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	intact-crc:2EBCFD9FD8256778|rigid:LodP/rjKS5JqThZEvzOOh8eUeMc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NUN5	uniprotkb:Q5NEB4	intact:EBI-2805231|ensembl:ENSP00000497690.1|uniprotkb:Q9NZD6|uniprotkb:Q86Y70|uniprotkb:Q96FW4|uniprotkb:Q9BY56|uniprotkb:A8K204|uniprotkb:Q5VUN6|uniprotkb:E1P531	intact:EBI-2797653|uniprotkb:A0A0G2RPR1	psi-mi:lmbd1_human(display_long)|uniprotkb:C6orf209(gene name synonym)|uniprotkb:NESI(gene name synonym)|uniprotkb:HDAg-L-interacting protein NESI(gene name synonym)|uniprotkb:LMBR1 domain-containing protein 1(gene name synonym)|uniprotkb:Nuclear export signal-interacting protein(gene name synonym)|uniprotkb:BM-021(orf name)|uniprotkb:CD001(orf name)|uniprotkb:MSTP044(orf name)|uniprotkb:LMBRD1(gene name)|psi-mi:LMBRD1(display_short)	psi-mi:q5neb4_fratt(display_long)|uniprotkb:yegQ(gene name)|psi-mi:yegQ(display_short)|uniprotkb:FTT_1726(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805228|imex:IM-13779-895	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168216.13(gene)|ensembl:ENST00000649934.3(transcript)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007369""(gastrulation)|go:""GO:0016020""(membrane)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0031419""(cobalamin binding)|go:""GO:0032050""(clathrin heavy chain binding)|go:""GO:0035612""(AP-2 adaptor complex binding)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0061462""(protein localization to lysosome)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0140318""(protein transporter activity)|interpro:IPR006876(LMBR1-like conserved region)|interpro:IPR050854|reactome:R-HSA-5683329|reactome:R-HSA-9758881|reactome:R-HSA-9758890|refseq:NP_060838.3|refseq:XP_011534243.1|efo:""Orphanet:79284""|panther:PTHR16130(orthology-group)"	"interpro:IPR001539(Peptidase U32)|refseq:YP_170628.1|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|interpro:IPR032525|refseq:WP_003022701.1|interpro:IPR051454"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Dw1UVIzcLg+gauw4KLA87WGuiKQ9606	rogid:V8v+igazfnHs0EcKm43UGRWNmrY177416	intact-crc:8EE2A4563E4404D1|rigid:UIGfRFkOg1CbjTb+3b+33dPPNCo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q4VP87	uniprotkb:Q8NHL6	intact:EBI-2796861	intact:EBI-2805262|uniprotkb:Q8NHK0|uniprotkb:Q8NHJ9|uniprotkb:O75025|uniprotkb:O75024|uniprotkb:A8MXT0|uniprotkb:A2IXV4|ensembl:ENSP00000480365.1|ensembl:ENSP00000481700.1	psi-mi:q4vp87_fratl(display_long)|uniprotkb:FTT0445(orf name)|uniprotkb:uup(gene name)|psi-mi:uup(display_short)	psi-mi:lirb1_human(display_long)|uniprotkb:ILT2(gene name synonym)|uniprotkb:LIR1(gene name synonym)|uniprotkb:MIR7(gene name synonym)|uniprotkb:CD85 antigen-like family member J(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 2(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 7(gene name synonym)|uniprotkb:LILRB1(gene name)|psi-mi:LILRB1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805271|imex:IM-13779-896	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|interpro:IPR027417|interpro:IPR032781|interpro:IPR051309"	"ensembl:ENSG00000274669.5(gene)|ensembl:ENSG00000277807.5(gene)|ensembl:ENST00000616408.4(transcript)|ensembl:ENST00000618055.4(transcript)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002230""(positive regulation of defense response to virus by host)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002309""(T cell proliferation involved in immune response)|rcsb pdb:6EWO|go:""GO:0002719""(negative regulation of cytokine production involved in immune response)|go:""GO:0002764""(immune response-regulating signaling pathway)|go:""GO:0002767""(immune response-inhibiting cell surface receptor signaling pathway)|go:""GO:0002774""(Fc receptor mediated inhibitory signaling pathway)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0009615""(response to virus)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014063""(negative regulation of serotonin secretion)|go:""GO:0023025""(MHC class Ib protein complex binding)|go:""GO:0023029""(MHC class Ib protein binding)|go:""GO:0030107""(HLA-A specific inhibitory MHC class I receptor activity)|go:""GO:0030109""(HLA-B specific inhibitory MHC class I receptor activity)|go:""GO:0031623""(receptor internalization)|go:""GO:0032393""(MHC class I receptor activity)|go:""GO:0032394""(MHC class Ib receptor activity)|go:""GO:0032396""(inhibitory MHC class I receptor activity)|go:""GO:0032688""(negative regulation of interferon-beta production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032693""(negative regulation of interleukin-10 production)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032945""(negative regulation of mononuclear cell proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046636""(negative regulation of alpha-beta T cell activation)|go:""GO:0051607""(defense response to virus)|go:""GO:0051926""(negative regulation of calcium ion transport)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0097028""(dendritic cell differentiation)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:2000669""(negative regulation of dendritic cell apoptotic process)|go:""GO:2001186""(negative regulation of CD8-positive, alpha-beta T cell activation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001193""(positive regulation of gamma-delta T cell activation involved in immune response)|go:""GO:2001199""(negative regulation of dendritic cell differentiation)|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050412|mint:Q8NHL6|rcsb pdb:1G0X|rcsb pdb:1P7Q|rcsb pdb:1UFU|rcsb pdb:1UGN|rcsb pdb:1VDG|rcsb pdb:3D2U|rcsb pdb:4LL9|rcsb pdb:4NO0|rcsb pdb:5KNM|rcsb pdb:6AEE|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6K60|rcsb pdb:6ZDX|rcsb pdb:7KFK|reactome:R-HSA-198933|refseq:NP_001075106.2|refseq:NP_001075107.2|refseq:NP_001075108.2|refseq:NP_001265327.2|refseq:NP_006660.4|refseq:NP_001265328.2|panther:PTHR11738(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+Qbmzj8eW72wb4LBUxcHkhpPQRE119856	rogid:c3bdpF4SePNjbOkhewak+Vj98hU9606	intact-crc:A05D20D303EAE2CE|rigid:X8vb+T7HgYaMR8bbk2ZuMu0gv1c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BT23	uniprotkb:Q5NEH1	intact:EBI-2805292|uniprotkb:Q96S91|uniprotkb:D3DU16|ensembl:ENSP00000259006.3|ensembl:ENSP00000462707.1|ensembl:ENSP00000464003.1	intact:EBI-2796391|uniprotkb:A0A0G2RMG3	psi-mi:limd2_human(display_long)|uniprotkb:SB143(orf name)|uniprotkb:LIMD2(gene name)|psi-mi:LIMD2(display_short)	psi-mi:q5neh1_fratt(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:FTT_1664(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805297|imex:IM-13779-901	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_085053.1|refseq:XP_005257760.1|refseq:XP_005257762.1|ensembl:ENSG00000136490.9(gene)|ensembl:ENST00000259006.8(transcript)|ensembl:ENST00000578061.5(transcript)|ensembl:ENST00000578402.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0046872""(metal ion binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR044115|rcsb pdb:2LZU|refseq:XP_006722187.1"	"go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_170571.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|refseq:WP_003022611.1|interpro:IPR036897|interpro:IPR036914"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GVO4AYJseVY+XWi45tx15LOJjpQ9606	rogid:YUFWDuTGDB9kX/RHTWI6fMTHxU0177416	intact-crc:D02A765C2FD2C94B|rigid:SYcc+4/P86umX6UsaK0/J/Ka0jU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF37	uniprotkb:Q08380	intact:EBI-2798724	intact:EBI-354956|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0|intact:EBI-40264365|uniprotkb:A0A0S2Z3Y1|ensembl:ENSP00000262776.2	psi-mi:syp_fratt(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1412(locus name)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805304|imex:IM-13779-900	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044140|refseq:YP_170355.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|interpro:IPR033730|refseq:WP_003022224.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR045864|interpro:IPR050062"	"refseq:NP_005558.1|ensembl:ENSG00000108679.13(gene)|ensembl:ENST00000262776.8(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006968""(cellular defense response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0031089""(platelet dense granule lumen)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR036772|interpro:IPR051481|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|panther:PTHR24410(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6/QkU5JRWJEBZMwaR9J83no0ffk177416	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	intact-crc:D3EFE9B14A245E92|rigid:AKpqSDiYTWJvi17gJtcrDC3pgnw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEB6	uniprotkb:Q08380	intact:EBI-2797029|uniprotkb:A0A0G2RNW9	intact:EBI-354956|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0|intact:EBI-40264365|uniprotkb:A0A0S2Z3Y1|ensembl:ENSP00000262776.2	psi-mi:q5neb6_fratt(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:FTT_1724c(locus name)	psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805311|imex:IM-13779-902	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:1990281""(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|refseq:YP_170626.1|refseq:WP_003022695.1|interpro:IPR051906"	"refseq:NP_005558.1|ensembl:ENSG00000108679.13(gene)|ensembl:ENST00000262776.8(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006968""(cellular defense response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0031089""(platelet dense granule lumen)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR036772|interpro:IPR051481|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|panther:PTHR24410(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rzu9m+ahxwjrbytyPusL6ALCJRw177416	rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606	intact-crc:65A97AB14A6A0DD8|rigid:elzO1OaaZruNi95Us90nxYTj4B0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGC7	uniprotkb:P53671	intact:EBI-2796378|uniprotkb:A0A0G2RMD1	intact:EBI-1384350|uniprotkb:Q7KZ80|uniprotkb:Q96E10|uniprotkb:Q99464|uniprotkb:A8K6H5|uniprotkb:Q9UFU0|uniprotkb:Q7L3H5|ensembl:ENSP00000332687.4	psi-mi:q5ngc7_fratt(display_long)|uniprotkb:FTT_0918(locus name)	psi-mi:limk2_human(display_long)|uniprotkb:LIMK2(gene name)|psi-mi:LIMK2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805285|imex:IM-13779-899	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_169915.1|interpro:IPR021956|refseq:WP_003020942.1	"refseq:NP_005560.1|refseq:NP_057952.1|refseq:NP_001026971.1|ensembl:ENSG00000182541.18(gene)|ensembl:ENST00000331728.9(transcript)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016310""(phosphorylation)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0060322""(head development)|go:""GO:0061303""(cornea development in camera-type eye)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0072686""(mitotic spindle)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1902018""(negative regulation of cilium assembly)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036034|interpro:IPR050940|mint:P53671|rcsb pdb:1X6A|rcsb pdb:4TPT|rcsb pdb:5NXD|rcsb pdb:7QHG|rcsb pdb:8GI4|rcsb pdb:8S3X|rcsb pdb:8WSW|reactome:R-HSA-3928662|reactome:R-HSA-416572|reactome:R-HSA-5627117|panther:PTHR46485(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PY6VBLnYAPBQCnx7Cz0BtZWqzy0177416	rogid:9Tt4TJshssdjMGb89YS+XrgJxDw9606	intact-crc:E6AB13B4B6260F06|rigid:zs3lF7Jy5KP9xh6DKCw5XuO8cDo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06239	uniprotkb:Q5NGF9	intact:EBI-1348|uniprotkb:P07100|uniprotkb:Q12850|uniprotkb:Q13152|uniprotkb:Q5TDH8|uniprotkb:Q5TDH9|uniprotkb:Q96DW4|uniprotkb:Q9NYT8|uniprotkb:Q7RTZ3|uniprotkb:D3DPP8|ensembl:ENSP00000337825.5	intact:EBI-2796712|uniprotkb:A0A0G2RMW7	psi-mi:lck_human(display_long)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:q5ngf9_fratt(display_long)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:FTT_0886(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805336|imex:IM-13779-904	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-553N|panther:PTHR24418(orthology-group)|efo:""Orphanet:280142""|ensembl:ENSG00000182866.18(gene)|ensembl:ENST00000336890.10(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001772""(immunological synapse)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030168""(platelet activation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0031295""(T cell costimulation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0042110""(T cell activation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051117""(ATPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051249""(regulation of lymphocyte activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1903039""(positive regulation of leukocyte cell-cell adhesion)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P06239|rcsb pdb:1BHF|rcsb pdb:1BHH|rcsb pdb:1CWD|rcsb pdb:1CWE|rcsb pdb:1FBZ|rcsb pdb:1H92|rcsb pdb:1IJR|rcsb pdb:1KIK|rcsb pdb:1LCJ|rcsb pdb:1LCK|rcsb pdb:1LKK|rcsb pdb:1LKL|rcsb pdb:1Q68|rcsb pdb:1Q69|rcsb pdb:1QPC|rcsb pdb:1QPD|rcsb pdb:1QPE|rcsb pdb:1QPJ|rcsb pdb:1X27|rcsb pdb:2IIM|rcsb pdb:2OF2|rcsb pdb:2OF4|rcsb pdb:2OFU|rcsb pdb:2OFV|rcsb pdb:2OG8|rcsb pdb:2PL0|rcsb pdb:2ZM1|rcsb pdb:2ZM4|rcsb pdb:2ZYB|rcsb pdb:3AC1|rcsb pdb:3AC2|rcsb pdb:3AC3|rcsb pdb:3AC4|rcsb pdb:3AC5|rcsb pdb:3AC8|rcsb pdb:3ACJ|rcsb pdb:3ACK|rcsb pdb:3AD4|rcsb pdb:3AD5|rcsb pdb:3AD6|rcsb pdb:3B2W|rcsb pdb:3BRH|rcsb pdb:3BYM|rcsb pdb:3BYO|rcsb pdb:3BYS|rcsb pdb:3BYU|rcsb pdb:3KMM|rcsb pdb:3KXZ|rcsb pdb:3LCK|rcsb pdb:3MPM|rcsb pdb:4C3F|rcsb pdb:4D8K|rcsb pdb:5MTM|rcsb pdb:5MTN|rcsb pdb:6H6A|rcsb pdb:6PDJ|rcsb pdb:8X2P|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-167590|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-6811558|reactome:R-HSA-9013407|reactome:R-HSA-9020558|reactome:R-HSA-9670439|reactome:R-HSA-9706374|refseq:NP_001036236.1|refseq:NP_005347.3"	"go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|refseq:YP_169883.1|interpro:IPR027417|refseq:WP_003020876.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/26	rogid:AIdRYIcSNXmD2ovQiEn9N4CWr/M9606	rogid:OSkw64bDGErXabpL9In6RSfdCEQ177416	intact-crc:F9530F949D4A9625|rigid:gJjCQSMhD/yeZ9UP2Y0QLsmqwK4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEL1	uniprotkb:Q86U70	intact:EBI-2805325	intact:EBI-677177|uniprotkb:O75479|uniprotkb:O96010|uniprotkb:Q1EQX1|uniprotkb:Q9UGM4|uniprotkb:B4DUC4|ensembl:ENSP00000501277.1	psi-mi:syc_fratt(display_long)|uniprotkb:Cysteinyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1616(locus name)|uniprotkb:cysS(gene name)|psi-mi:cysS(display_short)	psi-mi:ldb1_human(display_long)|uniprotkb:Nuclear LIM interactor(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:LDB1(gene name)|psi-mi:LDB1(display_short)|uniprotkb:CLIM2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805329|imex:IM-13779-905	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015803(Cysteinyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015273(Cysteinyl-tRNA synthetase, class Ia, DALR)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|refseq:YP_170531.1|interpro:IPR024909|go:""GO:0004817""(cysteine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006423""(cysteinyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|interpro:IPR032678|refseq:WP_003022540.1"	"refseq:NP_001106878.1|refseq:NP_003884.1|ensembl:ENSG00000198728.11(gene)|ensembl:ENST00000673968.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000972""(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001942""(hair follicle development)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007155""(cell adhesion)|go:""GO:0007399""(nervous system development)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0021702""(cerebellar Purkinje cell differentiation)|go:""GO:0022607""(cellular component assembly)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030274""(LIM domain binding)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0031252""(cell leading edge)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043549""(regulation of kinase activity)|go:""GO:0045647""(negative regulation of erythrocyte differentiation)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046985""(positive regulation of hemoglobin biosynthetic process)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1990907""(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR041363|mint:Q86U70|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:6TYD|rcsb pdb:7OB5|rcsb pdb:7OB8|rcsb pdb:8HIB|rcsb pdb:8SSU|rcsb pdb:9F5B|reactome:R-HSA-8939236|reactome:R-HSA-9010553|reactome:R-HSA-9733709|reactome:R-HSA-9752946|dip:DIP-31826N|panther:PTHR10378(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:pMiIpqmMZZrK8RXU9FBTTYhN2QQ177416	rogid:qvQKQuFDKim15gEBFj6MnxR6lTc9606	intact-crc:DDBB7A9EE84F8037|rigid:QzDUH94qux/PvNoCpXgguF73H2s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFN4	uniprotkb:P17931	intact:EBI-2796796	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:uvrb_fratt(display_long)|uniprotkb:Excinuclease ABC subunit B(gene name synonym)|uniprotkb:FTT_1199c(locus name)|uniprotkb:uvrB(gene name)|psi-mi:uvrB(display_short)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805318|imex:IM-13779-903	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170158.1|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004807(Excinuclease ABC, B subunit)|interpro:IPR024759|interpro:IPR027417|interpro:IPR036876|interpro:IPR041471|refseq:WP_003021449.1"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:Jhq9KYkHYrpyhq5qkOrHkcqCWVk177416	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:896FEA217A50D8DB|rigid:ejaZisDw5oErnD17VuflmWUDOyU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UIQ6	uniprotkb:Q5NHI8	intact:EBI-2805360|uniprotkb:O00769|uniprotkb:Q9TNQ2|uniprotkb:Q9TNQ3|uniprotkb:Q9UIQ7|uniprotkb:Q59H76|uniprotkb:Q15145|ensembl:ENSP00000231368.5	intact:EBI-2796130	psi-mi:lcap_human(display_long)|uniprotkb:OTASE(gene name synonym)|uniprotkb:Oxytocinase(gene name synonym)|uniprotkb:Insulin-regulated membrane aminopeptidase(gene name synonym)|uniprotkb:Insulin-responsive aminopeptidase(gene name synonym)|uniprotkb:Placental leucine aminopeptidase(gene name synonym)|uniprotkb:LNPEP(gene name)|psi-mi:LNPEP(display_short)	psi-mi:syr_fratt(display_long)|uniprotkb:argS(gene name)|psi-mi:argS(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0466c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805357|imex:IM-13779-909	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005566.2|refseq:NP_787116.2|ensembl:ENSG00000113441.16(gene)|ensembl:ENST00000231368.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0002480""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007565""(female pregnancy)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0042277""(peptide binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|interpro:IPR045357|interpro:IPR050344|mint:Q9UIQ6|rcsb pdb:4P8Q|rcsb pdb:4PJ6|rcsb pdb:4Z7I|rcsb pdb:5C97|rcsb pdb:5JHQ|rcsb pdb:5MJ6|rcsb pdb:7ZYF|rcsb pdb:8CGP|rcsb pdb:8CGW|rcsb pdb:8P0I|reactome:R-HSA-1236977|reactome:R-HSA-1445148|reactome:R-HSA-983168|panther:PTHR11533(orthology-group)"	"refseq:YP_169504.1|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|refseq:WP_003020254.1|interpro:IPR035684|interpro:IPR036695|go:""GO:0004814""(arginine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006420""(arginyl-tRNA aminoacylation)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IOU7GW8f6aBYAjIUQXFKbU5Hqkw9606	rogid:35Ja/VELqAtPlGCZ584Xgj51WEI177416	intact-crc:F2C74C31672E5378|rigid:9/wpAjbd7XdSfasIA+VdZCyXkrI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF74	uniprotkb:Q4G0J3	intact:EBI-2796785|uniprotkb:A0A0G2RND4	intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-25601393|intact:EBI-2560173|ensembl:ENSP00000344950.5|ensembl:ENSP00000421541.2|ensembl:ENSP00000422626.2|ensembl:ENSP00000499190.1|ensembl:ENSP00000511572.1	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805375|imex:IM-13779-907	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"ensembl:ENSG00000174720.18(gene)|ensembl:ENST00000344442.10(transcript)|ensembl:ENST00000505034.6(transcript)|ensembl:ENST00000509061.5(transcript)|ensembl:ENST00000651579.1(transcript)|ensembl:ENST00000694894.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000494""(""box C/D sno(s)RNA 3'-end processing"")|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008380""(RNA splicing)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0097322""(7SK snRNA binding)|go:""GO:0120259""(7SK snRNP)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1905382""(positive regulation of snRNA transcription by RNA polymerase II)|go:""GO:1990438""(U6 2'-O-snRNA methylation)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12|rcsb pdb:7SLP|rcsb pdb:7SLQ|refseq:NP_001253968.1|refseq:NP_056269.1|refseq:NP_057732.2|dip:DIP-47624N|efo:""Orphanet:319671""|panther:PTHR22792(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606	intact-crc:0A32596E2B43B959|rigid:pgoPLSX35uy1KGcnqxqXQf1Rfsg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06239	uniprotkb:Q5NF75	intact:EBI-1348|uniprotkb:P07100|uniprotkb:Q12850|uniprotkb:Q13152|uniprotkb:Q5TDH8|uniprotkb:Q5TDH9|uniprotkb:Q96DW4|uniprotkb:Q9NYT8|uniprotkb:Q7RTZ3|uniprotkb:D3DPP8|ensembl:ENSP00000337825.5	intact:EBI-2796541	psi-mi:lck_human(display_long)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:q5nf75_fratt(display_long)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:FTT_1368c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805343|imex:IM-13779-908	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-553N|panther:PTHR24418(orthology-group)|efo:""Orphanet:280142""|ensembl:ENSG00000182866.18(gene)|ensembl:ENST00000336890.10(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001772""(immunological synapse)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030168""(platelet activation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0031295""(T cell costimulation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0042110""(T cell activation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051117""(ATPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051249""(regulation of lymphocyte activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1903039""(positive regulation of leukocyte cell-cell adhesion)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P06239|rcsb pdb:1BHF|rcsb pdb:1BHH|rcsb pdb:1CWD|rcsb pdb:1CWE|rcsb pdb:1FBZ|rcsb pdb:1H92|rcsb pdb:1IJR|rcsb pdb:1KIK|rcsb pdb:1LCJ|rcsb pdb:1LCK|rcsb pdb:1LKK|rcsb pdb:1LKL|rcsb pdb:1Q68|rcsb pdb:1Q69|rcsb pdb:1QPC|rcsb pdb:1QPD|rcsb pdb:1QPE|rcsb pdb:1QPJ|rcsb pdb:1X27|rcsb pdb:2IIM|rcsb pdb:2OF2|rcsb pdb:2OF4|rcsb pdb:2OFU|rcsb pdb:2OFV|rcsb pdb:2OG8|rcsb pdb:2PL0|rcsb pdb:2ZM1|rcsb pdb:2ZM4|rcsb pdb:2ZYB|rcsb pdb:3AC1|rcsb pdb:3AC2|rcsb pdb:3AC3|rcsb pdb:3AC4|rcsb pdb:3AC5|rcsb pdb:3AC8|rcsb pdb:3ACJ|rcsb pdb:3ACK|rcsb pdb:3AD4|rcsb pdb:3AD5|rcsb pdb:3AD6|rcsb pdb:3B2W|rcsb pdb:3BRH|rcsb pdb:3BYM|rcsb pdb:3BYO|rcsb pdb:3BYS|rcsb pdb:3BYU|rcsb pdb:3KMM|rcsb pdb:3KXZ|rcsb pdb:3LCK|rcsb pdb:3MPM|rcsb pdb:4C3F|rcsb pdb:4D8K|rcsb pdb:5MTM|rcsb pdb:5MTN|rcsb pdb:6H6A|rcsb pdb:6PDJ|rcsb pdb:8X2P|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-167590|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-6811558|reactome:R-HSA-9013407|reactome:R-HSA-9020558|reactome:R-HSA-9670439|reactome:R-HSA-9706374|refseq:NP_001036236.1|refseq:NP_005347.3"	"go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|refseq:YP_170317.1|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/26	rogid:AIdRYIcSNXmD2ovQiEn9N4CWr/M9606	rogid:0p8bjZkiV/CFhcBBZu/jDbJCoI4177416	intact-crc:F3AF7E949ECC3C81|rigid:P3QEBJazU3CUHUUyV9iReb9MuQo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06239	uniprotkb:Q5NEG0	intact:EBI-1348|uniprotkb:P07100|uniprotkb:Q12850|uniprotkb:Q13152|uniprotkb:Q5TDH8|uniprotkb:Q5TDH9|uniprotkb:Q96DW4|uniprotkb:Q9NYT8|uniprotkb:Q7RTZ3|uniprotkb:D3DPP8|ensembl:ENSP00000337825.5	intact:EBI-2798280	psi-mi:lck_human(display_long)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:q5neg0_fratt(display_long)|uniprotkb:FTT_1676(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805350|imex:IM-13779-906	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-553N|panther:PTHR24418(orthology-group)|efo:""Orphanet:280142""|ensembl:ENSG00000182866.18(gene)|ensembl:ENST00000336890.10(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001772""(immunological synapse)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030168""(platelet activation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0031295""(T cell costimulation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0042110""(T cell activation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051117""(ATPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051249""(regulation of lymphocyte activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1903039""(positive regulation of leukocyte cell-cell adhesion)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P06239|rcsb pdb:1BHF|rcsb pdb:1BHH|rcsb pdb:1CWD|rcsb pdb:1CWE|rcsb pdb:1FBZ|rcsb pdb:1H92|rcsb pdb:1IJR|rcsb pdb:1KIK|rcsb pdb:1LCJ|rcsb pdb:1LCK|rcsb pdb:1LKK|rcsb pdb:1LKL|rcsb pdb:1Q68|rcsb pdb:1Q69|rcsb pdb:1QPC|rcsb pdb:1QPD|rcsb pdb:1QPE|rcsb pdb:1QPJ|rcsb pdb:1X27|rcsb pdb:2IIM|rcsb pdb:2OF2|rcsb pdb:2OF4|rcsb pdb:2OFU|rcsb pdb:2OFV|rcsb pdb:2OG8|rcsb pdb:2PL0|rcsb pdb:2ZM1|rcsb pdb:2ZM4|rcsb pdb:2ZYB|rcsb pdb:3AC1|rcsb pdb:3AC2|rcsb pdb:3AC3|rcsb pdb:3AC4|rcsb pdb:3AC5|rcsb pdb:3AC8|rcsb pdb:3ACJ|rcsb pdb:3ACK|rcsb pdb:3AD4|rcsb pdb:3AD5|rcsb pdb:3AD6|rcsb pdb:3B2W|rcsb pdb:3BRH|rcsb pdb:3BYM|rcsb pdb:3BYO|rcsb pdb:3BYS|rcsb pdb:3BYU|rcsb pdb:3KMM|rcsb pdb:3KXZ|rcsb pdb:3LCK|rcsb pdb:3MPM|rcsb pdb:4C3F|rcsb pdb:4D8K|rcsb pdb:5MTM|rcsb pdb:5MTN|rcsb pdb:6H6A|rcsb pdb:6PDJ|rcsb pdb:8X2P|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-167590|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-6811558|reactome:R-HSA-9013407|reactome:R-HSA-9020558|reactome:R-HSA-9670439|reactome:R-HSA-9706374|refseq:NP_001036236.1|refseq:NP_005347.3"	refseq:YP_170582.1|refseq:WP_003022628.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/26	rogid:AIdRYIcSNXmD2ovQiEn9N4CWr/M9606	rogid:D9zHvTFwh7040lhfI799Inv1GbA177416	intact-crc:BC98ED949FF1CED1|rigid:3KGNEfMC34h/oTNHK5s0c+wh+P4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID9	uniprotkb:Q96RT1	intact:EBI-2798201	intact:EBI-993903|uniprotkb:Q86W38|uniprotkb:Q9NR18|uniprotkb:Q9NW48|uniprotkb:Q9ULJ5|uniprotkb:A0AVR1|uniprotkb:B4E3F1|uniprotkb:B7ZLV9|uniprotkb:E9PCR8|uniprotkb:Q1RMD0|uniprotkb:E7EQW9|ensembl:ENSP00000284037.4	psi-mi:eftu_fratt(display_long)|uniprotkb:FTT_0137(locus name)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)	psi-mi:erbin_human(display_long)|uniprotkb:ERBIN(gene name)|psi-mi:ERBIN(display_short)|uniprotkb:Densin-180-like protein(gene name synonym)|uniprotkb:ERBB2IP(gene name synonym)|uniprotkb:Erbb2-interacting protein(gene name synonym)|uniprotkb:KIAA1225(gene name synonym)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Protein LAP2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805400|imex:IM-13779-913	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0097216""(guanosine tetraphosphate binding)|refseq:YP_169203.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR033720|interpro:IPR031157|refseq:WP_003028672.1|interpro:IPR041709|interpro:IPR050055"	"efo:""Orphanet:656912""|ensembl:ENSG00000112851.16(gene)|ensembl:ENST00000284037.10(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005176""(ErbB-2 class receptor binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005604""(basement membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030054""(cell junction)|go:""GO:0030056""(hemidesmosome)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0045175""(basal protein localization)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0070433""(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071638""(negative regulation of monocyte chemotactic protein-1 production)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099572""(postsynaptic specialization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|interpro:IPR050614|mint:Q96RT1|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1N7T|rcsb pdb:2H3L|rcsb pdb:2QBW|rcsb pdb:3CH8|rcsb pdb:6Q0M|rcsb pdb:6Q0N|rcsb pdb:6Q0U|rcsb pdb:6UBH|rcsb pdb:7LUL|reactome:R-HSA-1227986|reactome:R-HSA-8863795|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|refseq:NP_001006600.1|refseq:NP_001240626.1|refseq:NP_001240627.1|refseq:NP_001240628.1|refseq:NP_001240630.1|refseq:NP_061165.1|panther:PTHR45752(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h5xJZCtwL77bt8cg/p85MmX1c+E177416	rogid:kITHWAgafb7t7RFgzs5ff7XCL3Y9606	intact-crc:AE2940630A6476A9|rigid:cFU71pCxhY4miMzV3yEb308GZ+A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGI2	uniprotkb:Q15012	intact:EBI-2799802	intact:EBI-723416|uniprotkb:Q6UW22|ensembl:ENSP00000175091.4	psi-mi:rnph_fratt(display_long)|uniprotkb:tRNA nucleotidyltransferase(gene name synonym)|uniprotkb:FTT_0858(locus name)|uniprotkb:rph(gene name)|psi-mi:rph(display_short)	psi-mi:lap4a_human(display_long)|uniprotkb:Golgi 4-transmembrane-spanning transporter MTP(gene name synonym)|uniprotkb:LAPTM4A(gene name)|psi-mi:LAPTM4A(display_short)|uniprotkb:KIAA0108(gene name synonym)|uniprotkb:MTRP(gene name synonym)|uniprotkb:UNQ1846/PRO3574(orf name)|uniprotkb:LAPTM4(gene name synonym)|uniprotkb:MBNT(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805393|imex:IM-13779-910	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR002381(Ribonuclease phosphorolytic, bacterial-type)|interpro:IPR018336|refseq:YP_169860.1|interpro:IPR027408|go:""GO:0000049""(tRNA binding)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0006364""(rRNA processing)|go:""GO:0008033""(tRNA processing)|go:""GO:0009022""(tRNA nucleotidyltransferase activity)|go:""GO:0016075""(rRNA catabolic process)|refseq:WP_003020838.1|interpro:IPR036345|interpro:IPR050080"	"refseq:NP_055528.1|ensembl:ENSG00000068697.7(gene)|ensembl:ENST00000175091.5(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0031902""(late endosome membrane)|interpro:IPR004687(Golgi 4-transmembrane spanning transporter)|interpro:IPR018396|interpro:IPR051115|mint:Q15012|panther:PTHR12479(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:u3qShCbTaGy16VuExtjWVWb/iOg177416	rogid:dPn0OwVfUAs214sLqb7eZHTViNk9606	intact-crc:C6BDF75629935860|rigid:lwdmch8YuVg83AGns9YygOIZpXg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q4G0J3	uniprotkb:Q5NER5	intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-25601393|intact:EBI-2560173|ensembl:ENSP00000344950.5|ensembl:ENSP00000421541.2|ensembl:ENSP00000422626.2|ensembl:ENSP00000499190.1|ensembl:ENSP00000511572.1	intact:EBI-2805385|uniprotkb:A0A0G2RLZ1	psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name)	psi-mi:q5ner5_fratt(display_long)|uniprotkb:rnr(gene name)|psi-mi:rnr(display_short)|uniprotkb:FTT_1553c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805382|imex:IM-13779-912	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000174720.18(gene)|ensembl:ENST00000344442.10(transcript)|ensembl:ENST00000505034.6(transcript)|ensembl:ENST00000509061.5(transcript)|ensembl:ENST00000651579.1(transcript)|ensembl:ENST00000694894.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000494""(""box C/D sno(s)RNA 3'-end processing"")|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008380""(RNA splicing)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0097322""(7SK snRNA binding)|go:""GO:0120259""(7SK snRNP)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1905382""(positive regulation of snRNA transcription by RNA polymerase II)|go:""GO:1990438""(U6 2'-O-snRNA methylation)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12|rcsb pdb:7SLP|rcsb pdb:7SLQ|refseq:NP_001253968.1|refseq:NP_056269.1|refseq:NP_057732.2|dip:DIP-47624N|efo:""Orphanet:319671""|panther:PTHR22792(orthology-group)"	"interpro:IPR001900(Ribonuclease II and R)|refseq:YP_170477.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR022966|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011805(Ribonuclease R, bacterial)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008859""(exoribonuclease II activity)|refseq:WP_003022448.1|interpro:IPR050180"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606	rogid:8SCySYn77kDbuc3Azff0t+lyJiw177416	intact-crc:FEA0CA6E2B095619|rigid:3KoNBiT5HL/4JeLfZ3mK4dVwbgU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHS4	uniprotkb:P11279	intact:EBI-2798955|uniprotkb:A0A0G2RPB0	intact:EBI-2805407|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40|ensembl:ENSP00000333298.4|uniprotkb:B4DWL3	psi-mi:q5nhs4_fratt(display_long)|uniprotkb:Folylpolyglutamate synthetase(gene name synonym)|uniprotkb:Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase(gene name synonym)|uniprotkb:folC(gene name)|psi-mi:folC(display_short)|uniprotkb:Tetrahydrofolylpolyglutamate synthase(gene name synonym)|uniprotkb:FTT_0371c(locus name)	psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805415|imex:IM-13779-911	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001645(Folylpolyglutamate synthetase)|interpro:IPR013221(Mur ligase, central)|refseq:YP_169418.1|go:""GO:0004326""(tetrahydrofolylpolyglutamate synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008841""(dihydrofolate synthase activity)|go:""GO:0046654""(tetrahydrofolate biosynthetic process)|go:""GO:0046656""(folic acid biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_003020032.1|interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR036565|interpro:IPR036615"	"refseq:NP_005552.3|ensembl:ENSG00000185896.11(gene)|ensembl:ENST00000332556.5(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0001618""(virus receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0044754""(autolysosome)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0061474""(phagolysosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072594""(establishment of protein localization to organelle)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0140507""(granzyme-mediated programmed cell death signaling pathway)|go:""GO:1902513""(regulation of organelle transport along microtubule)|interpro:IPR002000(""Lysosome-associated membrane glycoprotein (Lamp)/CD68"")|interpro:IPR018134|interpro:IPR048524|interpro:IPR048528|mint:P11279|rcsb pdb:8ATH|rcsb pdb:8FY5|rcsb pdb:8FYF|reactome:R-HSA-6798695|dip:DIP-44670N|panther:PTHR11506(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:yCx5zGRSAd5ahIDsKUCa0YzZPVg177416	rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606	intact-crc:19970F74166F11DC|rigid:lNRXS71Vk42VoRhMKsNTMX77UIs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF37	uniprotkb:P14618	intact:EBI-2798724	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	psi-mi:syp_fratt(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1412(locus name)	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805451|imex:IM-13779-915	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044140|refseq:YP_170355.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|interpro:IPR033730|refseq:WP_003022224.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR045864|interpro:IPR050062"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:6/QkU5JRWJEBZMwaR9J83no0ffk177416	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	intact-crc:16DB17A5BF961FAC|rigid:QGR1p0tx5otK8LalONbC3kasNX0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P12956	uniprotkb:Q5NFN7	intact:EBI-353208|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|ensembl:ENSP00000352257.4|ensembl:ENSP00000353192.3|ensembl:ENSP00000384257.1|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8|intact:EBI-21355587	intact:EBI-2805432	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:q5nfn7_fratt(display_long)|uniprotkb:FTT_1196c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805429|imex:IM-13779-914	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001460.1|refseq:NP_001275905.1|ensembl:ENSG00000196419.13(gene)|ensembl:ENST00000359308.8(transcript)|ensembl:ENST00000360079.8(transcript)|ensembl:ENST00000405878.5(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000725""(recombinational repair)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000783""(nuclear telomere cap complex)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006266""(obsolete DNA ligation)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030332""(cyclin binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0043564""(""Ku70:Ku80 complex"")|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045621""(positive regulation of lymphocyte differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0051575""(5'-deoxyribose-5-phosphate lyase activity)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0071475""(cellular hyperosmotic salinity response)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097680""(double-strand break repair via classical nonhomologous end joining)|rcsb pdb:8ASC|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|interpro:IPR047087|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7Z6O|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:7ZT6|rcsb pdb:7ZVT|rcsb pdb:7ZWA|rcsb pdb:7ZYG|rcsb pdb:8AG4|rcsb pdb:8AG5|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|refseq:NP_001275906.1|dip:DIP-24188N|panther:PTHR12604(orthology-group)"	"interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|refseq:YP_170155.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015293""(symporter activity)|interpro:IPR036259|interpro:IPR051084"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/20	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rogid:JR7FSyGeDNqiL03fPnZTbiWaE4U177416	intact-crc:67ABD8C8AEEDF807|rigid:eeHCfN5Y6aEAnnCaRJ1I0CEZjUM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15230	uniprotkb:Q5NF74	intact:EBI-725060|uniprotkb:Q8WZA7|uniprotkb:Q9H1P1|uniprotkb:Q8TDF8|uniprotkb:Q5U4N9|ensembl:ENSP00000252999.3	intact:EBI-2796785|uniprotkb:A0A0G2RND4	psi-mi:lama5_human(display_long)|uniprotkb:LAMA5(gene name)|psi-mi:LAMA5(display_short)|uniprotkb:KIAA0533(gene name synonym)|uniprotkb:KIAA1907(gene name synonym)|uniprotkb:Laminin-10 subunit alpha(gene name synonym)|uniprotkb:Laminin-11 subunit alpha(gene name synonym)|uniprotkb:Laminin-15 subunit alpha(gene name synonym)	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805422|imex:IM-13779-916	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:521450""|ensembl:ENSG00000130702.15(gene)|ensembl:ENST00000252999.7(transcript)|go:""GO:0001658""(branching involved in ureteric bud morphogenesis)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0001942""(hair follicle development)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005610""(laminin-5 complex)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0007155""(cell adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007517""(muscle organ development)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030324""(lung development)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0036484""(trunk neural crest cell migration)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0043083""(synaptic cleft)|go:""GO:0043259""(laminin-10 complex)|go:""GO:0043260""(laminin-11 complex)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0050678""(regulation of epithelial cell proliferation)|go:""GO:0060271""(cilium assembly)|go:""GO:0060445""(branching involved in salivary gland morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098631""(cell adhesion mediator activity)|go:""GO:0098965""(extracellular matrix of synaptic cleft)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099173""(postsynapse organization)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR050440|mint:O15230|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-6785807|reactome:R-HSA-8874081|refseq:NP_005551.3|panther:PTHR24035(orthology-group)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rSTl5zwwQKcbd20buKGffFtl3jI9606	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	intact-crc:FA3B4AEF4F06D02D|rigid:LTQJtOcx/VHz7cKY0UrmqeSzK4o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFP9	uniprotkb:Q9NPI7	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	intact:EBI-2805442|uniprotkb:Q3B7J7|ensembl:ENSP00000340083.3|ensembl:ENSP00000499834.1	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	psi-mi:krcc1_human(display_long)|uniprotkb:CHBP2(gene name synonym)|uniprotkb:Cryptogenic hepatitis-binding protein 2(gene name synonym)|uniprotkb:BM-003(orf name)|uniprotkb:BM-044(orf name)|uniprotkb:KRCC1(gene name)|psi-mi:KRCC1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805439|imex:IM-13779-917	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	refseq:NP_001291455.1|refseq:NP_057702.1|ensembl:ENSG00000172086.9(gene)|ensembl:ENST00000347055.4(transcript)|ensembl:ENST00000672766.1(transcript)|mint:Q9NPI7|refseq:XP_016859781.1|dip:DIP-58940N|panther:PTHR46742(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	rogid:XhDNDZRzRP0oVJgkmgn4CrnQObQ9606	intact-crc:B92BA9819FB324E8|rigid:S9A1rcgq77Vtwl1ztmPpNibMqM8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEV5	uniprotkb:Q9Y2M5	intact:EBI-2805484|uniprotkb:A0A0G2RNG9	intact:EBI-714379|uniprotkb:Q5TZF2|uniprotkb:Q9H457|uniprotkb:B3KMA0|uniprotkb:Q5ZF45|ensembl:ENSP00000209884.4|uniprotkb:B4DUR0	psi-mi:q5nev5_fratt(display_long)|uniprotkb:xerC(gene name)|psi-mi:xerC(display_short)|uniprotkb:FTT_1503(locus name)	psi-mi:klh20_human(display_long)|uniprotkb:KLHL20(gene name)|psi-mi:KLHL20(display_short)|uniprotkb:KLEIP(gene name synonym)|uniprotkb:Kelch-like ECT2-interacting protein(gene name synonym)|uniprotkb:Kelch-like protein X(gene name synonym)|uniprotkb:KLHLX(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805488|imex:IM-13779-919	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013762(Integrase-like, catalytic core, phage)|interpro:IPR002104(Integrase, catalytic core, phage)|interpro:IPR004107(Integrase, N-terminal SAM-like, phage)|interpro:IPR023009|refseq:YP_170437.1|interpro:IPR044068|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006313""(DNA transposition)|go:""GO:0007059""(chromosome segregation)|go:""GO:0009037""(tyrosine-based site-specific recombinase activity)|go:""GO:0051301""(cell division)|refseq:WP_003014452.1|interpro:IPR010998(Integrase, Lamba-type, N-terminal)|interpro:IPR050090"	"refseq:NP_055273.2|refseq:XP_005245150.1|ensembl:ENSG00000076321.11(gene)|ensembl:ENST00000209884.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016605""(PML body)|go:""GO:0019964""(type II interferon binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:1990390""(protein K33-linked ubiquitination)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q9Y2M5|rcsb pdb:5YQ4|rcsb pdb:6GY5|rcsb pdb:8CIA|reactome:R-HSA-8951664|reactome:R-HSA-983168|panther:PTHR24412(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:piAKGJ9xjQhE3yenNrX0jTXNsX8177416	rogid:3MyNIHmvjvjumxy4csUdrbMg5wI9606	intact-crc:B0F3D71185285C36|rigid:ijfjHmWdXN/t1NBj/xQwbnW+XGA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFB1	uniprotkb:P14618	intact:EBI-2804572	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	psi-mi:gpmi_fratt(display_long)|uniprotkb:FTT_1329(locus name)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805458|imex:IM-13779-920	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|refseq:YP_170281.1|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|refseq:WP_003022072.1|interpro:IPR036646"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:hCl6sKvAA6k+SXkq3rxPT9kGowE177416	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	intact-crc:D6FA17A5BE4EB06D|rigid:GmlvxnTWiXlgRWLl2pmlIayKy60	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFN7	uniprotkb:Q96PQ7	intact:EBI-2805432	intact:EBI-2692595|uniprotkb:Q9Y2X2|uniprotkb:B7WP68|uniprotkb:Q86XW0|uniprotkb:A8K170|uniprotkb:Q9NVA9|uniprotkb:Q9NUK3|uniprotkb:Q9NV27|uniprotkb:F8WAE7|uniprotkb:Q6Y881|uniprotkb:E9PCF4|uniprotkb:G3XA92	psi-mi:q5nfn7_fratt(display_long)|uniprotkb:FTT_1196c(locus name)	psi-mi:klhl5_human(display_long)|uniprotkb:KLHL5(gene name)|psi-mi:KLHL5(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805477|imex:IM-13779-921	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|refseq:YP_170155.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015293""(symporter activity)|interpro:IPR036259|interpro:IPR051084"	"interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_057074.3|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR006652(Kelch repeat type 1)|refseq:NP_950240.2|mint:Q96PQ7|interpro:IPR030606|refseq:NP_001007076.1|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|reactome:R-HSA-8951664|reactome:R-HSA-983168|panther:PTHR24412(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JR7FSyGeDNqiL03fPnZTbiWaE4U177416	rogid:+A0OT194eLExAwwsaiUx1D8g6uQ9606	intact-crc:63B626EA40ED0C16|rigid:2pe8TCePJtBv+vpZToMV1aH1a0Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID2	uniprotkb:Q12918	intact:EBI-2796292	intact:EBI-2805465|uniprotkb:Q24K24|ensembl:ENSP00000229402.3	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	psi-mi:klrb1_human(display_long)|uniprotkb:CLEC5B(gene name synonym)|uniprotkb:NKRP1A(gene name synonym)|uniprotkb:C-type lectin domain family 5 member B(gene name synonym)|uniprotkb:HNKR-P1a(gene name synonym)|uniprotkb:Natural killer cell surface protein P1A(gene name synonym)|uniprotkb:KLRB1(gene name)|psi-mi:KLRB1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805470|imex:IM-13779-918	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"refseq:NP_002249.1|ensembl:ENSG00000111796.4(gene)|ensembl:ENST00000229402.4(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009986""(cell surface)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042269""(regulation of natural killer cell mediated cytotoxicity)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR051527|rcsb pdb:5MGR|rcsb pdb:5MGS|rcsb pdb:5MGT|reactome:R-HSA-198933|panther:PTHR46784(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	rogid:x6/pmu6Ty9fgVeNWFgk8bBYjvxc9606	intact-crc:4BD794CCAD759AB2|rigid:bZic/C4epKP9aUcNn++zL+R9jbs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60333	uniprotkb:Q5NGF9	intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4|ensembl:ENSP00000366290.1|ensembl:ENSP00000502065.1	intact:EBI-2796712|uniprotkb:A0A0G2RMW7	psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym)	psi-mi:q5ngf9_fratt(display_long)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:FTT_0886(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805502|imex:IM-13779-922	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:29072""|efo:""Orphanet:99946""|ensembl:ENSG00000054523.20(gene)|ensembl:ENST00000377086.5(transcript)|ensembl:ENST00000676179.1(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0006915""(apoptotic process)|go:""GO:0007270""(neuron-neuron synaptic transmission)|go:""GO:0007274""(neuromuscular synaptic transmission)|go:""GO:0008017""(microtubule binding)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019894""(kinesin binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0043005""(neuron projection)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:1902742""(apoptotic process involved in development)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990049""(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR032405|interpro:IPR036961|interpro:IPR049780|mint:O60333|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N|panther:PTHR24115(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|refseq:YP_169883.1|interpro:IPR027417|refseq:WP_003020876.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/28	rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606	rogid:OSkw64bDGErXabpL9In6RSfdCEQ177416	intact-crc:9E36E6CB89B870A5|rigid:zCOIONv1x1VFppbi18eii9Zsbtc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIG6	uniprotkb:Q9P2E2	intact:EBI-2797019|uniprotkb:A0A0G2RNE6	intact:EBI-949612|uniprotkb:O95077|uniprotkb:Q53YS6|uniprotkb:Q5VWA9|uniprotkb:Q6GSA8|uniprotkb:Q8N411|uniprotkb:A2A3Q7|uniprotkb:A2A3Q8|ensembl:ENSP00000247986.2	psi-mi:q5nig6_fratt(display_long)|uniprotkb:FTT_0106c(locus name)	psi-mi:kif17_human(display_long)|uniprotkb:KIF3-related motor protein(gene name synonym)|uniprotkb:KIF17(gene name)|psi-mi:KIF17(display_short)|uniprotkb:KIAA1405(gene name synonym)|uniprotkb:KIF3X(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805509|imex:IM-13779-925	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:1990281""(efflux pump complex)|interpro:IPR006143(Secretion protein HlyD)|refseq:YP_169176.1|interpro:IPR032317|refseq:WP_003019844.1"	"refseq:NP_001116291.1|refseq:NP_065867.2|refseq:NP_001274141.1|ensembl:ENSG00000117245.13(gene)|ensembl:ENST00000247986.2(transcript)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0005929""(cilium)|go:""GO:0005930""(axoneme)|go:""GO:0008017""(microtubule binding)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0015031""(protein transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030030""(cell projection organization)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043005""(neuron projection)|go:""GO:0098794""(postsynapse)|go:""GO:0098971""(anterograde dendritic transport of neurotransmitter receptor complex)|go:""GO:1990075""(periciliary membrane compartment)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q9P2E2|reactome:R-HSA-5620924|reactome:R-HSA-9609736|panther:PTHR24115(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:j9DdAUzigby9ZKoJN5AFW0d27v4177416	rogid:EXTRC6rf1yPUFuLt/b+qqt8tSpM9606	intact-crc:5D174D116345DA40|rigid:OyjMiBlgQY0hyNKhjwcjXhNE0co	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFR9	uniprotkb:O43896	intact:EBI-2796367|uniprotkb:A0A0G2RN39	intact:EBI-1644048|uniprotkb:O75186|uniprotkb:Q5U618|uniprotkb:D3DTL6|ensembl:ENSP00000320821.5	psi-mi:q5nfr9_fratt(display_long)|uniprotkb:pilQ(gene name)|psi-mi:pilQ(display_short)|uniprotkb:FTT_1156c(locus name)	psi-mi:kif1c_human(display_long)|uniprotkb:KIF1C(gene name)|psi-mi:KIF1C(display_short)|uniprotkb:KIAA0706(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805495|imex:IM-13779-924	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009306""(protein secretion)|interpro:IPR001775(Bacterial general secretion pathway protein D)|interpro:IPR005644(NolW-like)|interpro:IPR013355(Type IV pilus secretin PilQ)|interpro:IPR011662(Secretin/TonB, short N-terminal)|interpro:IPR004846(Type II and III secretion system)|interpro:IPR004845(Type II secretion system gspD, conserved site)|refseq:YP_170123.1|refseq:WP_003021368.1|interpro:IPR038591|interpro:IPR051808"	"dip:DIP-40376N|ensembl:ENSG00000129250.12(gene)|ensembl:ENST00000320785.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0008017""(microtubule binding)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990048""(anterograde neuronal dense core vesicle transport)|go:""GO:1990049""(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR027417|interpro:IPR032405|interpro:IPR036961|mint:O43896|rcsb pdb:2G1L|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_006603.2|refseq:XP_005256481.1|efo:""Orphanet:397946""|panther:PTHR24115(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:5Bv1oL/eG4begMb5a4sn4z1n/jk177416	rogid:AeG87fdDj70xFfsQCPuXA9iiubo9606	intact-crc:3CA190167C6CC076|rigid:yseBcwo1+IhBqDLPgWQY24sLX1Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31321	uniprotkb:Q79RC1	intact:EBI-2805516|uniprotkb:Q8N422|ensembl:ENSP00000353415.4|ensembl:ENSP00000385349.1|ensembl:ENSP00000385749.1|ensembl:ENSP00000440449.1|ensembl:ENSP00000444487.1	intact:EBI-2800505	psi-mi:kap1_human(display_long)|uniprotkb:PRKAR1B(gene name)|psi-mi:PRKAR1B(display_short)	psi-mi:q79rc1_fratl(display_long)|uniprotkb:manB(gene name)|psi-mi:manB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805521|imex:IM-13779-923	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000188191.16(gene)|ensembl:ENST00000360274.8(transcript)|ensembl:ENST00000403562.5(transcript)|ensembl:ENST00000406797.5(transcript)|ensembl:ENST00000537384.6(transcript)|ensembl:ENST00000544935.5(transcript)|go:""GO:0004862""(cAMP-dependent protein kinase inhibitor activity)|go:""GO:0005771""(multivesicular body)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0007611""(learning or memory)|go:""GO:0008603""(cAMP-dependent protein kinase regulator activity)|go:""GO:0030552""(cAMP binding)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0097546""(ciliary base)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098693""(regulation of synaptic vesicle cycle)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0141162""(negative regulation of cAMP/PKA signal transduction)|go:""GO:1900273""(positive regulation of long-term synaptic potentiation)|go:""GO:1903367""(positive regulation of fear response)|go:""GO:2000463""(positive regulation of excitatory postsynaptic potential)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR042818|interpro:IPR050503|mint:P31321|rcsb pdb:4DIN|rcsb pdb:4F9K|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9856530|refseq:NP_001158230.1|refseq:NP_001158231.1|refseq:NP_001158232.1|refseq:NP_001158233.1|refseq:NP_001158234.1|refseq:NP_002726.1|efo:""Orphanet:412066""|panther:PTHR11635(orthology-group)"	"refseq:WP_003022277.1|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004615""(phosphomannomutase activity)|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0008966""(phosphoglucosamine mutase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|interpro:IPR036900|interpro:IPR050060"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lHJ5CQLoIXsPDtmgJgb34zho6B89606	rogid:VditS6r1AnxfAC5K+EjyPlNcTkE119856	intact-crc:73687CF9918B21F8|rigid:P5hR0xYtaWNZ84GMe9TZdKdy0tA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI74	uniprotkb:P01834	intact:EBI-2797356|uniprotkb:A0A0G2RNT1	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:q5ni74_fratt(display_long)|uniprotkb:FTT_0209c(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805552|imex:IM-13779-927	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0007155""(cell adhesion)|go:""GO:0030001""(metal ion transport)|go:""GO:0046872""(metal ion binding)|interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006129(Adhesin B)|refseq:YP_169268.1|refseq:WP_003017523.1|interpro:IPR050492"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SNzKG6SXy0yUlUpZyU9sv3eNyRk177416	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:BF5237DCB68DB558|rigid:hjlLTczaPmkT3624Vx/H/kKDZ2E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIF3	uniprotkb:P01834	intact:EBI-2805542|uniprotkb:A0A0G2RQ85	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:q5nif3_fratt(display_long)|uniprotkb:FTT_0119(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805545|imex:IM-13779-929	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018392|refseq:YP_169189.1|go:""GO:0016020""(membrane)|refseq:WP_003019870.1|interpro:IPR036779"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h8z6Md6/RUQQaYkf/0SDUSXFJqs177416	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:3E7337DCB709E5E0|rigid:kB9X9vdMJp2HjD1svN45C4nM47Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHY6	uniprotkb:P01834	intact:EBI-2796153	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:sye_fratt(display_long)|uniprotkb:gltX(gene name)|psi-mi:gltX(display_short)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0307(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805528|imex:IM-13779-928	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169356.1|interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004527(Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020058|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:WP_003021625.1|interpro:IPR033910|interpro:IPR045462|interpro:IPR049940|go:""GO:0000049""(tRNA binding)|go:""GO:0004818""(glutamate-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006424""(glutamyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6DvyR/b9UNDoFX+nMfvtqGvLXt4177416	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:756146DCB62059D0|rigid:aNd9bzoeKIDbdprOgMZft/28yzw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:Q5NGM6	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2798999	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:recr_fratt(display_long)|uniprotkb:FTT_0809c(locus name)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805535|imex:IM-13779-926	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|refseq:YP_169816.1|go:""GO:0003677""(DNA binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0046872""(metal ion binding)|refseq:WP_003020731.1|interpro:IPR034137"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:tEJFaj0sBjlO63/t6qZChWG6RU4177416	intact-crc:334C99DCB624E6AB|rigid:pkQP7ughS3P67n/QPzdG2rFry1U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEX4	uniprotkb:P01834	intact:EBI-2800250|uniprotkb:A0A0G2RPH4	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:q5nex4_fratt(display_long)|uniprotkb:lpd(gene name)|psi-mi:lpd(display_short)|uniprotkb:FTT_1483c(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805566|imex:IM-13779-930	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|refseq:YP_170418.1|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_003022339.1|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR036188|interpro:IPR050151"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M7P/eSKN5XPGALvQBQLWvlqQ7fY177416	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:2F537BDCB699F815|rigid:UPTKbjrjAWLCqx2t3dsn/AI8Kj0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEB5	uniprotkb:P01834	intact:EBI-2800848|uniprotkb:A0A0G2RN83	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:q5neb5_fratt(display_long)|uniprotkb:pcm(gene name)|psi-mi:pcm(display_short)|uniprotkb:Protein L-isoaspartyl methyltransferase(gene name synonym)|uniprotkb:FTT_1725c(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805580|imex:IM-13779-931	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029063|refseq:YP_170627.1|go:""GO:0004719""(""protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0032259""(methylation)|go:""GO:0036211""(protein modification process)|refseq:WP_003022697.1|interpro:IPR000682(""Protein-L-isoaspartate(D-aspartate) O-methyltransferase"")"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DR7Nkx1bHGD6J7T6JdSRsZBuowM177416	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:88297BDCB6C2969E|rigid:aeZJAwvBBpgXQ1FLwkagXU+4EuA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:Q5NF60	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2799293	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:dnlj_fratt(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:""Polydeoxyribonucleotide synthase [NAD(+)]""(gene name synonym)|uniprotkb:FTT_1387c(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805587|imex:IM-13779-934	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"refseq:YP_170332.1|interpro:IPR001357(BRCT)|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR004149(Zinc-finger, NAD-dependent DNA ligase C4-type)|go:""GO:0003677""(DNA binding)|go:""GO:0003911""(""DNA ligase (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006288""(obsolete base-excision repair, DNA ligation)|go:""GO:0046872""(metal ion binding)|refseq:WP_003024021.1|interpro:IPR033136|interpro:IPR036420|interpro:IPR041663"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:rHqrcgB9uMgr4visMI6R3FjEECc177416	intact-crc:42DAE8DCB7FE1733|rigid:9zBhFZ0wJfEsJ9H+KfmoZKYib88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV7	uniprotkb:P01834	intact:EBI-2796192	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:katg_fratt(display_long)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:FTT_0721c(locus name)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805559|imex:IM-13779-932	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169735.1|interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|refseq:WP_003020536.1|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UVLspYdPWJwb7VPBG0xNq1Pp2KQ177416	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:D94799DCB67FD4DF|rigid:dIu6/nFfzKdm3+uB/ZHCTpB2VHQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:Q5NEJ4	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2799894|uniprotkb:A0A0G2RQA6	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:q5nej4_fratt(display_long)|uniprotkb:ftsK(gene name)|psi-mi:ftsK(display_short)|uniprotkb:FTT_1635(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805573|imex:IM-13779-933	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"interpro:IPR002543(Cell divisionFtsK/SpoIIIE)|interpro:IPR018541|refseq:YP_170548.1|interpro:IPR027417|interpro:IPR025199|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007059""(chromosome segregation)|go:""GO:0051301""(cell division)|refseq:WP_003022567.1|interpro:IPR036388|interpro:IPR036390|interpro:IPR041027|interpro:IPR050206"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:MHG0tEU4NHSPB6cp/UeAYw2sOLQ177416	intact-crc:72A17BDCB69C8E1C|rigid:zCnxlo17v4RqQzKx8ERvHWtAEfA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q2KHM9	uniprotkb:Q5NES9	intact:EBI-2805604|uniprotkb:Q2KHN0|uniprotkb:Q9UG45|uniprotkb:O94853|uniprotkb:A8KA11|uniprotkb:B7Z479|uniprotkb:Q05D97|ensembl:ENSP00000355250.3	intact:EBI-2799997|uniprotkb:A0A0G2RNU2	psi-mi:moonr_human(display_long)|uniprotkb:KIAA0753(gene name)|psi-mi:KIAA0753(display_short)|uniprotkb:MNR(gene name synonym)|uniprotkb:OFD1- and FOPNL-interacting protein(gene name synonym)|uniprotkb:OFIP(gene name synonym)	psi-mi:q5nes9_fratt(display_long)|uniprotkb:FTT_1534c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805601|imex:IM-13779-937	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-61716N|efo:""Orphanet:2754""|efo:""Orphanet:474""|efo:""Orphanet:475""|ensembl:ENSG00000198920.11(gene)|ensembl:ENST00000361413.8(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0007099""(centriole replication)|go:""GO:0034451""(centriolar satellite)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0060271""(cilium assembly)|go:""GO:0061824""(cytosolic ciliogenesis)|go:""GO:0071539""(protein localization to centrosome)|interpro:IPR031447|mint:Q2KHM9|refseq:NP_055619.2|refseq:XP_006721675.1|refseq:XP_016880945.1|panther:PTHR15732(orthology-group)"	"interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|refseq:YP_170463.1|go:""GO:0009435""(NAD biosynthetic process)|go:""GO:0047280""(nicotinamide phosphoribosyltransferase activity)|refseq:WP_003018116.1|interpro:IPR036068|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR041525|interpro:IPR041529"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/17	rogid:3VyGPv3YYzpSoaCWulihyoxODOA9606	rogid:0+HtF7EvtGUcHmfq6JdVWnUFZs8177416	intact-crc:746A65F5B30C2C2D|rigid:RI1Isyext5yirvkNHW+04ZbRcPM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGM6	uniprotkb:O75071	intact:EBI-2798999	intact:EBI-2805635|uniprotkb:Q5SXB8|uniprotkb:D3DQ23|ensembl:ENSP00000361001.3	psi-mi:recr_fratt(display_long)|uniprotkb:FTT_0809c(locus name)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)	psi-mi:efc14_human(display_long)|uniprotkb:EFCAB14(gene name)|psi-mi:EFCAB14(display_short)|uniprotkb:KIAA0494(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805640|imex:IM-13779-938	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|refseq:YP_169816.1|go:""GO:0003677""(DNA binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0046872""(metal ion binding)|refseq:WP_003020731.1|interpro:IPR034137"	"refseq:NP_055589.1|ensembl:ENSG00000159658.15(gene)|ensembl:ENST00000371933.8(transcript)|go:""GO:0005509""(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR042352|panther:PTHR15717(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tEJFaj0sBjlO63/t6qZChWG6RU4177416	rogid:UhD1cgnq+/XOmI2Y7LZ7ANpf9wA9606	intact-crc:E28DC2155E6B9400|rigid:u6cRuf5BpdwsXFDw+ZfC9PROvUg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A7E2V4	uniprotkb:Q5NHN4	intact:EBI-947995|uniprotkb:Q17RS8|uniprotkb:Q2TAB8|uniprotkb:Q6P439|uniprotkb:Q8IW81|uniprotkb:Q8NB34|uniprotkb:Q9H8F3|uniprotkb:O94987|uniprotkb:B2RP37|ensembl:ENSP00000474748.1	intact:EBI-2797896	psi-mi:zswm8_human(display_long)|uniprotkb:ZSWIM8(gene name)|psi-mi:ZSWIM8(display_short)|uniprotkb:KIAA0913(gene name synonym)	"psi-mi:glgb_fratt(display_long)|uniprotkb:""1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase""(gene name synonym)|uniprotkb:FTT_0413c(locus name)|uniprotkb:glgB(gene name)|psi-mi:glgB(display_short)|uniprotkb:""Alpha-(1->4)-glucan branching enzyme""(gene name synonym)|uniprotkb:Glycogen branching enzyme(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805594|imex:IM-13779-935	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229416.1|refseq:NP_001229417.1|refseq:NP_055852.2|refseq:XP_006717788.1|ensembl:ENSG00000214655.11(gene)|ensembl:ENST00000605216.5(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0140958""(target-directed miRNA degradation)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000627""(positive regulation of miRNA catabolic process)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR048370|mint:A7E2V4|reactome:R-HSA-9010553|panther:PTHR22619(orthology-group)"	"go:""GO:0003844""(1,4-alpha-glucan branching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005829""(cytosol)|go:""GO:0005978""(glycogen biosynthetic process)|go:""GO:0043169""(cation binding)|interpro:IPR037439|interpro:IPR044143|refseq:YP_169458.1|interpro:IPR006407(1,4-alpha-glucan branching enzyme, core region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_003020147.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:L/Zc7H24cEC7qtYp34nahN0pKEc9606	rogid:r21IlnrFbxbAaYAD68mDKpyeQwI177416	intact-crc:81C847ECFE02935F|rigid:Hfj1mG3BBMNc0F+t52vb7vweOxo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A2RU30	uniprotkb:Q5NGF9	intact:EBI-2805618|ensembl:ENSP00000312679.8|ensembl:ENSP00000400892.1|uniprotkb:B4E048|uniprotkb:O94849|uniprotkb:Q9P0C4|uniprotkb:B4DPM3|uniprotkb:B7Z9K7|uniprotkb:Q4G0P2	intact:EBI-2796712|uniprotkb:A0A0G2RMW7	psi-mi:tesp1_human(display_long)|uniprotkb:TESPA1(gene name)|psi-mi:TESPA1(display_short)|uniprotkb:KIAA0748(gene name synonym)|uniprotkb:Thymocyte-expressed positive selection-associated protein 1(gene name synonym)|uniprotkb:HSPC257(orf name)	psi-mi:q5ngf9_fratt(display_long)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:FTT_0886(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805628|imex:IM-13779-936	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000135426.16(gene)|ensembl:ENST00000316577.12(transcript)|ensembl:ENST00000449076.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0008104""(protein localization)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0010387""(COP9 signalosome assembly)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033089""(positive regulation of T cell differentiation in thymus)|go:""GO:0036398""(TCR signalosome)|go:""GO:0036399""(TCR signalosome assembly)|go:""GO:0043274""(phospholipase binding)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|interpro:IPR029325|interpro:IPR043444|refseq:XP_011537337.1|refseq:XP_011537338.1|refseq:XP_011537339.1|refseq:NP_001092285.1|refseq:NP_001129502.1|refseq:NP_001248773.1|refseq:NP_055611.1|refseq:XP_005269304.1|refseq:XP_006719778.1|refseq:XP_016875751.1|refseq:XP_016875752.1|panther:PTHR17469(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|refseq:YP_169883.1|interpro:IPR027417|refseq:WP_003020876.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mZKdiLJJ3HATJbt/OSGGgeLw9i89606	rogid:OSkw64bDGErXabpL9In6RSfdCEQ177416	intact-crc:E495C225442B726F|rigid:lELAp5wTzOmQB+ytc2MWB52gOsc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF31	uniprotkb:Q14154	intact:EBI-2801218|uniprotkb:A0A0G2RNH8	intact:EBI-2805660|uniprotkb:Q969R4|uniprotkb:Q96EU9|intact:EBI-2831226|ensembl:ENSP00000194118.4|ensembl:ENSP00000396225.2	psi-mi:q5nf31_fratt(display_long)|uniprotkb:nusB(gene name)|psi-mi:nusB(display_short)|uniprotkb:Antitermination factor NusB(gene name synonym)|uniprotkb:FTT_1418c(locus name)	psi-mi:dele1_human(display_long)|uniprotkb:DELE1(gene name)|psi-mi:DELE1(display_short)|uniprotkb:DELE(gene name synonym)|uniprotkb:Death ligand signal enhancer(gene name synonym)|uniprotkb:KIAA0141(gene name synonym)|uniprotkb:DAP3-binding cell death enhancer 1, long form(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805666|imex:IM-13779-940	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011605(NusB antitermination factor)|interpro:IPR006027(NusB/RsmB/TIM44)|refseq:YP_170361.1|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|refseq:WP_003022234.1|interpro:IPR035926"	"refseq:NP_001136075.1|refseq:NP_055588.3|refseq:XP_005268604.1|refseq:XP_005268605.1|ensembl:ENSG00000081791.9(gene)|ensembl:ENST00000194118.8(transcript)|ensembl:ENST00000432126.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0033554""(cellular response to stress)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0140468""(HRI-mediated signaling)|go:""GO:1901526""(positive regulation of mitophagy)|go:""GO:1990641""(response to iron ion starvation)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR052748|rcsb pdb:8D9X|reactome:R-HSA-9840373|panther:PTHR45011(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qmu3F+Cf/c260g8lVqz2f62Wpp0177416	rogid:UBQ+baEp+eubj9KvSTnUTdJLq9g9606	intact-crc:41DD5826AEF8EEB5|rigid:EymOOwLSCa5i869wAp0igfIanyA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFK7	uniprotkb:Q93073	intact:EBI-2797846|uniprotkb:A0A0G2RN70	intact:EBI-2805647|uniprotkb:Q8N767|ensembl:ENSP00000453854.1	psi-mi:q5nfk7_fratt(display_long)|uniprotkb:rne(gene name)|psi-mi:rne(display_short)|uniprotkb:FTT_1227(locus name)	psi-mi:sbp2l_human(display_long)|uniprotkb:KIAA0256(gene name synonym)|uniprotkb:SECISBP2L(gene name)|psi-mi:SECISBP2L(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805653|imex:IM-13779-939	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006364""(rRNA processing)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008033""(tRNA processing)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008995""(ribonuclease E activity)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019843""(rRNA binding)|interpro:IPR028878|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR019307|interpro:IPR004659(Ribonuclease E and G)|refseq:YP_170185.1|refseq:WP_003021514.1|interpro:IPR048583"	"refseq:NP_001180418.1|refseq:NP_055516.2|ensembl:ENSG00000138593.9(gene)|ensembl:ENST00000559471.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0035368""(selenocysteine insertion sequence binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|interpro:IPR040051|mint:Q93073|panther:PTHR13284(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:T1YeruV0gQXSr2JVi+sAPAQCsl0177416	rogid:h2ByJoTHpYKWrIRaWpnqy4LbkUk9606	intact-crc:267730EA3F7130C9|rigid:deJsz1urWTKCcUZCV1hZcoAcHN8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHQ9	uniprotkb:P05412	intact:EBI-2803576	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1	psi-mi:glms_fratt(display_long)|uniprotkb:GFAT(gene name synonym)|uniprotkb:Glucosamine-6-phosphate synthase(gene name synonym)|uniprotkb:Hexosephosphate aminotransferase(gene name synonym)|uniprotkb:D-fructose-6-phosphate amidotransferase(gene name synonym)|uniprotkb:glmS(gene name)|psi-mi:glmS(display_short)|uniprotkb:L-glutamine--D-fructose-6-phosphate amidotransferase(gene name synonym)|uniprotkb:FTT_0388(locus name)	psi-mi:jun_human(display_long)|uniprotkb:Transcription factor AP-1 subunit Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805693|imex:IM-13779-942	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017932|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR001347(""Sugar isomerase (SIS)"")|refseq:YP_169433.1|rcsb pdb:3TBF|go:""GO:0004360""(""glutamine-fructose-6-phosphate transaminase (isomerizing) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006002""(fructose 6-phosphate metabolic process)|go:""GO:0006047""(UDP-N-acetylglucosamine metabolic process)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0097367""(carbohydrate derivative binding)|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490|interpro:IPR047084|refseq:WP_003020072.1|interpro:IPR046348"	"refseq:NP_002219.1|panther:PTHR11462(orthology-group)|ensembl:ENSG00000177606.9(gene)|ensembl:ENST00000371222.4(transcript)|ensembl:ENST00000678696.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0019046""(release from viral latency)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035976""(transcription factor AP-1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR050946|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|rcsb pdb:8SOS|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324|reactome:R-HSA-9725370|dip:DIP-5961N|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:JsL9z5rmv6AL2wzoOZ/eVktGZqw177416	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	intact-crc:134F74AC6D540AB3|rigid:/8Q7rWVGFZKU1U/5ZLR0lJVTsWY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NE83	uniprotkb:P05412	intact:EBI-2798034|uniprotkb:A0A0G2RMP3	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1	psi-mi:q5ne83_fratt(display_long)|uniprotkb:FTT_1768c(locus name)	psi-mi:jun_human(display_long)|uniprotkb:Transcription factor AP-1 subunit Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805686|imex:IM-13779-944	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008843""(endochitinase activity)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:YP_170659.1|interpro:IPR050542"	"refseq:NP_002219.1|panther:PTHR11462(orthology-group)|ensembl:ENSG00000177606.9(gene)|ensembl:ENST00000371222.4(transcript)|ensembl:ENST00000678696.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0019046""(release from viral latency)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035976""(transcription factor AP-1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR050946|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|rcsb pdb:8SOS|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324|reactome:R-HSA-9725370|dip:DIP-5961N|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:W2y1WmdkLbyjKn567ANSSuNPpHo177416	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	intact-crc:56B549AC6F1F8898|rigid:9/WAJDNF38dk4Gk23g42dfDykpU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A384DVV8	uniprotkb:Q5NET8	intact:EBI-20764875|uniprotkb:A0A024R935|ensembl:ENSP00000478803.1|uniprotkb:A0A024R946	intact:EBI-2797750|uniprotkb:A0A0G2RM76	psi-mi:a0a384dvv8_human(display_long)|uniprotkb:KIAA0040(gene name)|psi-mi:KIAA0040(display_short)	psi-mi:q5net8_fratt(display_long)|uniprotkb:hrpA(gene name)|psi-mi:hrpA(display_short)|uniprotkb:FTT_1524c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805679|imex:IM-13779-941	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	ensembl:ENSG00000235750.10(gene)|ensembl:ENST00000619513.1(transcript)|refseq:XP_016858398.1|refseq:XP_016858399.1	"go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170454.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR024590|interpro:IPR010222(RNA helicase, ATP-dependent DEAH box, HrpA type)|interpro:IPR027417|refseq:WP_003022403.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DUc4LZSkM+XjbIzKIiI9q8rkO/M9606	rogid:dwTrOZ+V/pe0RndqVFMFAdvwFAM177416	intact-crc:9A019E9C0D1FCF87|rigid:MTzuRD+EcMZJ/gf1ZZ9mKhh2/Pg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NQC1	uniprotkb:Q5NF27	intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q6IE80|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q96GQ6|ensembl:ENSP00000378451.1	intact:EBI-2797283	psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym)	psi-mi:q5nf27_fratt(display_long)|uniprotkb:FTT_1422(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805707|imex:IM-13779-943	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143.22(gene)|ensembl:ENST00000395003.5(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000278""(regulation of DNA biosynthetic process)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|interpro:IPR050701|mint:Q9NQC1|reactome:R-HSA-3214847|panther:PTHR13793(orthology-group)"	"go:""GO:0008198""(ferrous iron binding)|go:""GO:0031418""(L-ascorbic acid binding)|go:""GO:0031543""(peptidyl-proline dioxygenase activity)|go:""GO:0071456""(cellular response to hypoxia)|interpro:IPR005123(""2OG-Fe(II) oxygenase"")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|refseq:YP_170365.1|interpro:IPR044862|interpro:IPR051559"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606	rogid:JC9olxh4wMmKqfNgjUEBhgQ+X0I177416	intact-crc:4BADF4DDDED53EAF|rigid:oqGryqn1vSNeAajD3YUMDQH0OGY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O76095	uniprotkb:Q5NFP9	intact:EBI-2339818|uniprotkb:Q6IB19|uniprotkb:Q9P0Q4|uniprotkb:O95442|ensembl:ENSP00000271843.4	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:jtb_human(display_long)|uniprotkb:JTB(gene name)|psi-mi:JTB(display_short)|uniprotkb:Jumping translocation breakpoint protein(gene name synonym)|uniprotkb:Prostate androgen-regulated protein(gene name synonym)|uniprotkb:HSPC222(orf name)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805700|imex:IM-13779-945	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006685.1|ensembl:ENSG00000143543.15(gene)|ensembl:ENST00000271843.9(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005886""(plasma membrane)|go:""GO:0008637""(apoptotic mitochondrial changes)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030496""(midbody)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0045860""(positive regulation of protein kinase activity)|interpro:IPR008657(Jumping translocation breakpoint)|mint:O76095|rcsb pdb:2KJX|panther:PTHR13041(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+kbmONvsTzUE4lzJz9nQFBInol49606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:28587BDB059F0475|rigid:ToM+weKQJAUZVNH5pHo3fcydu0s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NQC1	uniprotkb:Q5NEB5	intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q6IE80|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q96GQ6|ensembl:ENSP00000378451.1	intact:EBI-2800848|uniprotkb:A0A0G2RN83	psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym)	psi-mi:q5neb5_fratt(display_long)|uniprotkb:pcm(gene name)|psi-mi:pcm(display_short)|uniprotkb:Protein L-isoaspartyl methyltransferase(gene name synonym)|uniprotkb:FTT_1725c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805714|imex:IM-13779-948	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143.22(gene)|ensembl:ENST00000395003.5(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000278""(regulation of DNA biosynthetic process)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|interpro:IPR050701|mint:Q9NQC1|reactome:R-HSA-3214847|panther:PTHR13793(orthology-group)"	"interpro:IPR029063|refseq:YP_170627.1|go:""GO:0004719""(""protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0032259""(methylation)|go:""GO:0036211""(protein modification process)|refseq:WP_003022697.1|interpro:IPR000682(""Protein-L-isoaspartate(D-aspartate) O-methyltransferase"")"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606	rogid:DR7Nkx1bHGD6J7T6JdSRsZBuowM177416	intact-crc:739A67DDDE7E3091|rigid:5gFw7+hZMjELAf1Q5mfm0LyhHgw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q969R8	uniprotkb:Q5NI93	intact:EBI-723695|uniprotkb:Q96SX6|uniprotkb:A8K4Z5|uniprotkb:D3DUQ2|uniprotkb:Q6PKU5|ensembl:ENSP00000228799.2	intact:EBI-2796455|uniprotkb:A0A0G2RN73	psi-mi:itfg2_human(display_long)|uniprotkb:ITFG2(gene name)|psi-mi:ITFG2(display_short)|uniprotkb:Integrin-alpha FG-GAP repeat-containing protein 2(gene name synonym)	psi-mi:q5ni93_fratt(display_long)|uniprotkb:ftsZ(gene name)|psi-mi:ftsZ(display_short)|uniprotkb:FTT_0188(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805735|imex:IM-13779-947	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060933.3|ensembl:ENSG00000111203.13(gene)|ensembl:ENST00000228799.7(transcript)|go:""GO:0002314""(germinal center B cell differentiation)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0032006""(regulation of TOR signaling)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0140007""(KICSTOR complex)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR028994|interpro:IPR031793|interpro:IPR036322|reactome:R-HSA-9639288|panther:PTHR16317(orthology-group)"	"go:""GO:0000917""(division septum assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|go:""GO:0051258""(protein polymerization)|refseq:YP_169249.1|interpro:IPR020805|interpro:IPR000158(Cell division protein FtsZ, N-terminal)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR037103|interpro:IPR024757|refseq:WP_003017491.1|interpro:IPR036525|interpro:IPR045061"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ObfKtEatDvMO8/SUSh0ViFZcksc9606	rogid:p6oFxKWqOxuojnYBsnj2aLlMQbw177416	intact-crc:403659113B76FE3E|rigid:h/Q7qFG9DMMp3oMJNmbGlPgc1Zg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIQ1	uniprotkb:Q9NZM3	intact:EBI-2798606|uniprotkb:A0A0G2RN49	intact:EBI-308689|uniprotkb:O95062|uniprotkb:Q15812|uniprotkb:Q9HAK4|uniprotkb:Q9NXE6|uniprotkb:Q9NYG0|uniprotkb:Q9NZM2|uniprotkb:Q9ULG4|ensembl:ENSP00000347244.4	psi-mi:q5niq1_fratt(display_long)|uniprotkb:purB(gene name)|psi-mi:purB(display_short)|uniprotkb:FTT_0015(locus name)	psi-mi:itsn2_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short)|uniprotkb:KIAA1256(gene name synonym)|uniprotkb:SH3D1B(gene name synonym)|uniprotkb:SWAP(gene name synonym)|uniprotkb:SH3 domain-containing protein 1B(gene name synonym)|uniprotkb:SH3P18(gene name synonym)|uniprotkb:SH3P18-like WASP-associated protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805721|imex:IM-13779-946	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000362(Fumarate lyase)|interpro:IPR020557|interpro:IPR008948(L-Aspartase-like)|interpro:IPR024083|interpro:IPR022761|interpro:IPR004769(Adenylosuccinate lyase)|refseq:YP_169091.1|go:""GO:0000166""(nucleotide binding)|go:""GO:0004018""(""N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0044208""('de novo' AMP biosynthetic process)|go:""GO:0070626""(""(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"")|rcsb pdb:4EEI|refseq:WP_003022846.1|rcsb pdb:5HW2"	"refseq:NP_006268.2|refseq:NP_062541.3|refseq:NP_671494.2|ensembl:ENSG00000198399.16(gene)|ensembl:ENST00000355123.9(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016197""(endosomal transport)|go:""GO:0030154""(cell differentiation)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0150007""(clathrin-dependent synaptic vesicle endocytosis)|go:""GO:1903861""(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR000261(""EPS15 homology (EH)"")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|interpro:IPR051480|mint:Q9NZM3|rcsb pdb:1J3T|rcsb pdb:1UDL|rcsb pdb:1UE9|rcsb pdb:1UFF|rcsb pdb:1UHF|rcsb pdb:3GF9|rcsb pdb:3JZY|rcsb pdb:4IIO|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013420|panther:PTHR11216(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UF//jrwcet55761YffVdb0dDwfg177416	rogid:dxUqeWmW1uwOqgZ89UhT98/pt809606	intact-crc:774AE520300EEF6F|rigid:8ZM5xvgGGcwHuQPQENKO+5u+Zxw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14573	uniprotkb:Q5NGF1	intact:EBI-351055|uniprotkb:Q14649|uniprotkb:Q5TAQ2|intact:EBI-28978202|ensembl:ENSP00000363435.4|ensembl:ENSP00000475177.1	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	psi-mi:itpr3_human(display_long)|uniprotkb:ITPR3(gene name)|psi-mi:ITPR3(display_short)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 3(gene name synonym)	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805728|imex:IM-13779-949	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002215.2|ensembl:ENSG00000096433.11(gene)|ensembl:ENST00000374316.9(transcript)|ensembl:ENST00000605930.3(transcript)|go:""GO:0000822""(inositol hexakisphosphate binding)|go:""GO:0005220""(inositol 1,4,5-trisphosphate-gated calcium channel activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007613""(memory)|go:""GO:0015278""(intracellularly gated calcium channel activity)|go:""GO:0016020""(membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0030168""(platelet activation)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043235""(receptor complex)|go:""GO:0043533""(inositol 1,3,4,5 tetrakisphosphate binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0050909""(sensory perception of taste)|go:""GO:0050913""(sensory perception of bitter taste)|go:""GO:0050916""(sensory perception of sweet taste)|go:""GO:0050917""(sensory perception of umami taste)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0051592""(response to calcium ion)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR015925(Ryanodine receptor-related)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14573|rcsb pdb:6DQJ|rcsb pdb:6DQN|rcsb pdb:6DQS|rcsb pdb:6DQV|rcsb pdb:6DQZ|rcsb pdb:6DR0|rcsb pdb:6DR2|rcsb pdb:6DRA|rcsb pdb:6DRC|rcsb pdb:6UQK|rcsb pdb:7T3P|rcsb pdb:7T3Q|rcsb pdb:7T3R|rcsb pdb:7T3T|rcsb pdb:7T3U|rcsb pdb:8TK8|rcsb pdb:8TKD|rcsb pdb:8TKE|rcsb pdb:8TKF|rcsb pdb:8TKG|rcsb pdb:8TKH|rcsb pdb:8TKI|rcsb pdb:8TL9|rcsb pdb:8TLA|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-9717207|reactome:R-HSA-983695|panther:PTHR13715(orthology-group)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:O+1OC4E0IrAOt+D672eXnhWHy3I9606	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	intact-crc:D057DD7ECD8141AF|rigid:P7qWBBeIol5zex9XkEQR/P8aJeo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHP0	uniprotkb:Q96J02	intact:EBI-2798584	intact:EBI-1564678|uniprotkb:O43584|uniprotkb:Q5TEL0|uniprotkb:Q96F66|uniprotkb:Q9BY75|uniprotkb:Q9H451|uniprotkb:Q9H4U5|uniprotkb:A6NEW4|uniprotkb:Q5QP37|uniprotkb:E1P5P3|uniprotkb:B4E234|uniprotkb:F5H217|ensembl:ENSP00000262650.5|ensembl:ENSP00000499786.1	psi-mi:gcst_fratt(display_long)|uniprotkb:Glycine cleavage system T protein(gene name synonym)|uniprotkb:FTT_0407(locus name)|uniprotkb:gcvT(gene name)|psi-mi:gcvT(display_short)	psi-mi:itch_human(display_long)|uniprotkb:HECT-type E3 ubiquitin transferase Itchy homolog(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 4(gene name synonym)|uniprotkb:NFE2-associated polypeptide 1(gene name synonym)|uniprotkb:ITCH(gene name)|psi-mi:ITCH(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805742|imex:IM-13779-950	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013977(Glycine cleavage T-protein, C-terminal barrel)|interpro:IPR006222(Glycine cleavage T-protein, N-terminal)|interpro:IPR006223(Glycine cleavage system T protein)|interpro:IPR022903|refseq:YP_169452.1|go:""GO:0004047""(aminomethyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0008483""(transaminase activity)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|interpro:IPR029043|refseq:WP_003020116.1|interpro:IPR028896|interpro:IPR027266"	"efo:""Orphanet:228426""|panther:PTHR11254(orthology-group)|dip:DIP-29849N|ensembl:ENSG00000078747.17(gene)|ensembl:ENST00000262650.11(transcript)|ensembl:ENST00000665346.1(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002669""(positive regulation of T cell anergy)|go:""GO:0002870""(T cell anergy)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016874""(ligase activity)|go:""GO:0019787""(ubiquitin-like protein transferase activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034450""(ubiquitin-ubiquitin ligase activity)|go:""GO:0035519""(protein K29-linked ubiquitination)|go:""GO:0035739""(CD4-positive, alpha-beta T cell proliferation)|go:""GO:0035872""(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:""GO:0039532""(negative regulation of cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045236""(CXCR chemokine receptor binding)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050687""(negative regulation of defense response to virus)|go:""GO:0051607""(defense response to virus)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0060544""(regulation of necroptotic process)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0090085""(regulation of protein deubiquitination)|go:""GO:0141198""(protein branched polyubiquitination)|go:""GO:1902036""(regulation of hematopoietic stem cell differentiation)|go:""GO:1990763""(arrestin family protein binding)|go:""GO:2000562""(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|interpro:IPR050409|mint:Q96J02|rcsb pdb:2DMV|rcsb pdb:2KYK|rcsb pdb:2NQ3|rcsb pdb:2P4R|rcsb pdb:2YSF|rcsb pdb:3TUG|rcsb pdb:4ROF|rcsb pdb:5C7M|rcsb pdb:5CQ2|rcsb pdb:5DWS|rcsb pdb:5DZD|rcsb pdb:5SXP|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-2122948|reactome:R-HSA-5610780|reactome:R-HSA-5632684|reactome:R-HSA-5675482|reactome:R-HSA-8939236|reactome:R-HSA-936440|reactome:R-HSA-9692916|reactome:R-HSA-983168|refseq:NP_001244066.1|refseq:NP_001244067.1|refseq:NP_001311126.1|refseq:NP_001311127.1|refseq:NP_113671.3|refseq:XP_016883578.1|refseq:XP_016883580.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:mKJNdMRkysAgSP3xcjX6RESGsZ4177416	rogid:JyySOfI+ZHOI1mvdxWDGN6njgCY9606	intact-crc:E8A46B5DA15FA8E8|rigid:NowsflLzJjVDw38xKN628FWB69M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEU6	uniprotkb:P05107	intact:EBI-2799541|uniprotkb:A0A0G2RNM1	intact:EBI-300173|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1|ensembl:ENSP00000347279.4|ensembl:ENSP00000380948.2|ensembl:ENSP00000380950.1|ensembl:ENSP00000380955.1|ensembl:ENSP00000498780.1	psi-mi:q5neu6_fratt(display_long)|uniprotkb:dnaJ2(gene name)|psi-mi:dnaJ2(display_short)|uniprotkb:FTT_1512c(locus name)	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805770|imex:IM-13779-952	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|refseq:YP_170446.1|go:""GO:0005737""(cytoplasm)|go:""GO:0042026""(protein refolding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|refseq:WP_003022390.1|interpro:IPR036869"	"efo:""Orphanet:99842""|ensembl:ENSG00000160255.19(gene)|ensembl:ENST00000355153.8(transcript)|ensembl:ENST00000397850.6(transcript)|ensembl:ENST00000397852.5(transcript)|ensembl:ENST00000397857.5(transcript)|ensembl:ENST00000652462.1(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0002523""(leukocyte migration involved in inflammatory response)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008305""(integrin complex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030369""(ICAM-3 receptor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031623""(receptor internalization)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034687""(integrin alphaL-beta2 complex)|go:""GO:0034688""(integrin alphaM-beta2 complex)|go:""GO:0034689""(integrin alphaX-beta2 complex)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0043113""(receptor clustering)|go:""GO:0043235""(receptor complex)|go:""GO:0043315""(positive regulation of neutrophil degranulation)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045123""(cellular extravasation)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045963""(negative regulation of dopamine metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1990266""(neutrophil migration)|go:""GO:2000363""(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|mint:P05107|rcsb pdb:1L3Y|rcsb pdb:1YUK|rcsb pdb:2JF1|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|rcsb pdb:4NEH|rcsb pdb:4NEN|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|rcsb pdb:7P2D|rcsb pdb:7USL|rcsb pdb:7USM|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|panther:PTHR10082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/01	rogid:vfCNiJP7u4fjKjv/1B6pZtA2dug177416	rogid:Q/zG7M9MczNRx1TBKx4rXH+87iY9606	intact-crc:BA66160893E7CA19|rigid:cGWTCylkFxgX/k3xrZ6AltIUt6o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFR6	uniprotkb:P16144	intact:EBI-2805749|uniprotkb:A0A0G2RPW1	intact:EBI-948678|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97|ensembl:ENSP00000200181.3	psi-mi:q5nfr6_fratt(display_long)|uniprotkb:FTT_1159c(locus name)	psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805752|imex:IM-13779-951	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_170126.1|go:""GO:0016020""(membrane)|refseq:WP_003018618.1|interpro:IPR052534|interpro:IPR007813(Fimbrial assembly)"	"dip:DIP-40182N|efo:""Orphanet:1114""|efo:""Orphanet:158684""|efo:""Orphanet:251393""|efo:""Orphanet:79402""|efo:""Orphanet:79403""|ensembl:ENSG00000132470.14(gene)|ensembl:ENST00000200181.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006914""(autophagy)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009611""(response to wounding)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030054""(cell junction)|go:""GO:0030056""(hemidesmosome)|go:""GO:0031252""(cell leading edge)|go:""GO:0031581""(hemidesmosome assembly)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032290""(peripheral nervous system myelin formation)|go:""GO:0035878""(nail development)|go:""GO:0043235""(receptor complex)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0046847""(filopodium assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048870""(cell motility)|go:""GO:0061450""(trophoblast cell migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|reactome:R-HSA-9725554|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1|panther:PTHR10082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:ZGrhF6ZRRAtrXluCqZFMV/qGUc0177416	rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606	intact-crc:4978A93BC7F25DBC|rigid:wbNqNDtWTAFICgm5PQzMKSXrBLo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF37	uniprotkb:P56199	intact:EBI-2798724	intact:EBI-2554465|uniprotkb:B2RNU0|ensembl:ENSP00000282588.5	psi-mi:syp_fratt(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1412(locus name)	psi-mi:ita1_human(display_long)|uniprotkb:ITGA1(gene name)|psi-mi:ITGA1(display_short)|uniprotkb:Laminin and collagen receptor(gene name synonym)|uniprotkb:VLA-1(gene name synonym)|uniprotkb:CD49 antigen-like family member A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805777|imex:IM-13779-954	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044140|refseq:YP_170355.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|interpro:IPR033730|refseq:WP_003022224.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR045864|interpro:IPR050062"	"refseq:NP_852478.1|dip:DIP-206N|ensembl:ENSG00000213949.10(gene)|ensembl:ENST00000282588.7(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008305""(integrin complex)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019211""(phosphatase activator activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034665""(integrin alpha1-beta1 complex)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042311""(vasodilation)|go:""GO:0043204""(perikaryon)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045123""(cellular extravasation)|go:""GO:0045178""(basal part of cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|interpro:IPR048285|interpro:IPR048286|mint:P56199|rcsb pdb:1PT6|rcsb pdb:1QC5|rcsb pdb:1QCY|rcsb pdb:2L8S|rcsb pdb:2M32|rcsb pdb:4A0Q|rcsb pdb:5HGJ|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-416700|reactome:R-HSA-445355|reactome:R-HSA-447041|reactome:R-HSA-75892|panther:PTHR23220(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/08	rogid:6/QkU5JRWJEBZMwaR9J83no0ffk177416	rogid:rI8GnpuQlkN7TAnJ2eLpECEZOxs9606	intact-crc:6EEA592DA76B3E73|rigid:T4rzcuaNLy6+SZsvhyK+PnbECmc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16144	uniprotkb:Q5NH47	intact:EBI-948678|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97|ensembl:ENSP00000200181.3	intact:EBI-2805762	psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short)	psi-mi:clpp_fratt(display_long)|uniprotkb:Endopeptidase Clp(gene name synonym)|uniprotkb:FTT_0624(locus name)|uniprotkb:clpP(gene name)|psi-mi:clpP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805759|imex:IM-13779-953	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-40182N|efo:""Orphanet:1114""|efo:""Orphanet:158684""|efo:""Orphanet:251393""|efo:""Orphanet:79402""|efo:""Orphanet:79403""|ensembl:ENSG00000132470.14(gene)|ensembl:ENST00000200181.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006914""(autophagy)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009611""(response to wounding)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030054""(cell junction)|go:""GO:0030056""(hemidesmosome)|go:""GO:0031252""(cell leading edge)|go:""GO:0031581""(hemidesmosome assembly)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032290""(peripheral nervous system myelin formation)|go:""GO:0035878""(nail development)|go:""GO:0043235""(receptor complex)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0046847""(filopodium assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048870""(cell motility)|go:""GO:0061450""(trophoblast cell migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|reactome:R-HSA-9725554|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1|panther:PTHR10082(orthology-group)"	"interpro:IPR023562|interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|refseq:YP_169645.1|rcsb pdb:3P2L|interpro:IPR029045|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0009368""(endopeptidase Clp complex)|go:""GO:0051117""(ATPase binding)|refseq:WP_003015534.1|interpro:IPR033135|rcsb pdb:5G1Q|rcsb pdb:5G1R|rcsb pdb:5G1S"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606	rogid:JkviZnvM5s4hSy7KP/0TifRewqA177416	intact-crc:FF3A073BC7B85435|rigid:ayQOhoeDQ93heJpB/WuPqujoV4w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:Q13576	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-357571|uniprotkb:J3KR91|uniprotkb:A8K4V1|uniprotkb:B7Z8A4|ensembl:ENSP00000274364.6	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:iqga2_human(display_long)|uniprotkb:IQGAP2(gene name)|psi-mi:IQGAP2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805812|imex:IM-13779-956	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_001272391.1|refseq:NP_006624.2|ensembl:ENSG00000145703.17(gene)|ensembl:ENST00000274364.11(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0009986""(cell surface)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030175""(filopodium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070493""(thrombin-activated receptor signaling pathway)|go:""GO:0071933""(Arp2/3 complex binding)|go:""GO:1903479""(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|mint:Q13576|rcsb pdb:3IEZ|rcsb pdb:4EZA|rcsb pdb:5CJP|reactome:R-HSA-5626467|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-27542N|panther:PTHR14149(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:gmxbOFcisiWIsQrHFQCoI5y49T09606	intact-crc:F9DAD4A6E32FCAF7|rigid:LSjllRluVxHBwDNea8OR1GCpzoE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15051	uniprotkb:Q5NIB3	intact:EBI-2805823|uniprotkb:Q9BS08|uniprotkb:Q5DKQ7|uniprotkb:Q8NI79|uniprotkb:Q3KS08|uniprotkb:Q3KS09|ensembl:ENSP00000311505.6	intact:EBI-2805819|uniprotkb:A0A0G2RPX7	psi-mi:iqcb1_human(display_long)|uniprotkb:KIAA0036(gene name synonym)|uniprotkb:NPHP5(gene name synonym)|uniprotkb:Nephrocystin-5(gene name synonym)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short)|uniprotkb:p53 and DNA damage-regulated IQ motif protein(gene name synonym)|uniprotkb:OK/SW-cl.85(orf name)	psi-mi:q5nib3_fratt(display_long)|uniprotkb:parE(gene name)|psi-mi:parE(display_short)|uniprotkb:Topoisomerase IV subunit B(gene name synonym)|uniprotkb:FTT_0163c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805830|imex:IM-13779-958	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000173226.17(gene)|ensembl:ENST00000310864.11(transcript)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0019899""(enzyme binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0045171""(intercellular bridge)|go:""GO:0045494""(photoreceptor cell maintenance)|go:""GO:0048496""(maintenance of animal organ identity)|go:""GO:0060271""(cilium assembly)|go:""GO:0061824""(cytosolic ciliogenesis)|go:""GO:0062063""(BBSome binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072686""(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR028765|mint:Q15051|reactome:R-HSA-5620912|refseq:NP_001018864.2|refseq:NP_001018865.2|refseq:NP_001306036.1|efo:""Orphanet:3156""|efo:""Orphanet:65""|panther:PTHR15673(orthology-group)"	"refseq:YP_169229.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR005737(DNA topoisomerase IV, subunit B, Gram-negative)|interpro:IPR006171(TOPRIM)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0006265""(DNA topological change)|go:""GO:0007059""(chromosome segregation)|go:""GO:0034335""(DNA negative supercoiling activity)|refseq:WP_003019941.1|interpro:IPR036890"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gNs0xsyI7Tu3pHu7GhdQDn8tuy89606	rogid:eSUwaDHwHNDsicxk7YgYrDfmnIE177416	intact-crc:169F27615DF99156|rigid:zUPel/5RrxeKYYtQcg65zFrFuwI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48200	uniprotkb:Q5NEC0	intact:EBI-2805796|uniprotkb:Q59FQ7|uniprotkb:A8KAC7|uniprotkb:Q1HE21|uniprotkb:Q13095|uniprotkb:Q9UF17|ensembl:ENSP00000258886.8|uniprotkb:E1CJT9|uniprotkb:H0YKU0|uniprotkb:Q8WVK6|uniprotkb:A0A0A6YY96	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:ireb2_human(display_long)|uniprotkb:Iron regulatory protein 2(gene name synonym)|uniprotkb:IREB2(gene name)|psi-mi:IREB2(display_short)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805805|imex:IM-13779-957	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004127.1|refseq:NP_001307870.1|refseq:NP_001307872.1|ensembl:ENSG00000136381.13(gene)|ensembl:ENST00000258886.13(transcript)|go:""GO:0000900""(mRNA regulatory element binding translation repressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006101""(citrate metabolic process)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0009791""(post-embryonic development)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030350""(iron-responsive element binding)|go:""GO:0034101""(erythrocyte homeostasis)|go:""GO:0046872""(metal ion binding)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0050892""(intestinal absorption)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR036008|interpro:IPR044137|rcsb pdb:6VCD|reactome:R-HSA-917937|panther:PTHR11670(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CLTD+3OeZFZsevsGz0F80POtkK49606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:16F1B8EAA444CDE2|rigid:UMT1f5RV588Ob+gqGSEDqfPXij0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96CN7	uniprotkb:Q5NFR9	intact:EBI-2805787|uniprotkb:Q7Z770|intact:EBI-2831451|ensembl:ENSP00000173527.5	intact:EBI-2796367|uniprotkb:A0A0G2RN39	psi-mi:isoc1_human(display_long)|uniprotkb:CGI-111(orf name)|uniprotkb:ISOC1(gene name)|psi-mi:ISOC1(display_short)	psi-mi:q5nfr9_fratt(display_long)|uniprotkb:pilQ(gene name)|psi-mi:pilQ(display_short)|uniprotkb:FTT_1156c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805784|imex:IM-13779-955	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057132.2|ensembl:ENSG00000066583.12(gene)|go:""GO:0005737""(cytoplasm)|ensembl:ENST00000173527.6(transcript)|go:""GO:0005777""(peroxisome)|interpro:IPR000868(Isochorismatase hydrolase)|interpro:IPR036380|interpro:IPR050993|mint:Q96CN7|panther:PTHR14119(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0009306""(protein secretion)|interpro:IPR001775(Bacterial general secretion pathway protein D)|interpro:IPR005644(NolW-like)|interpro:IPR013355(Type IV pilus secretin PilQ)|interpro:IPR011662(Secretin/TonB, short N-terminal)|interpro:IPR004846(Type II and III secretion system)|interpro:IPR004845(Type II secretion system gspD, conserved site)|refseq:YP_170123.1|refseq:WP_003021368.1|interpro:IPR038591|interpro:IPR051808"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wByhW87LRND2MYhLLnYg1/t8Cxk9606	rogid:5Bv1oL/eG4begMb5a4sn4z1n/jk177416	intact-crc:95D35B5B12BB28E9|rigid:vm0g4ecw2nbu88rnbObzZDvro90	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:P15260	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-1030755|uniprotkb:Q53Y96|uniprotkb:E1P587|uniprotkb:B4DFT7|ensembl:ENSP00000356713.5	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:ingr1_human(display_long)|uniprotkb:IFNGR1(gene name)|psi-mi:IFNGR1(display_short)|uniprotkb:CDw119(gene name synonym)|uniprotkb:Interferon gamma receptor alpha-chain(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805851|imex:IM-13779-960	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"dip:DIP-47N|efo:""Orphanet:117""|efo:""Orphanet:319569""|efo:""Orphanet:319581""|efo:""Orphanet:99898""|ensembl:ENSG00000027697.16(gene)|ensembl:ENST00000367739.9(transcript)|go:""GO:0001774""(microglial cell activation)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0004906""(type II interferon receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0009615""(response to virus)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019955""(cytokine binding)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0038196""(type III interferon-mediated signaling pathway)|go:""GO:0048143""(astrocyte activation)|go:""GO:0051607""(defense response to virus)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0098586""(cellular response to virus)|go:""GO:1900222""(negative regulation of amyloid-beta clearance)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008355(Interferon-gamma receptor alpha chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR021126|interpro:IPR036116|interpro:IPR050650|mint:P15260|rcsb pdb:1FG9|rcsb pdb:1FYH|rcsb pdb:1JRH|rcsb pdb:6E3K|rcsb pdb:6E3L|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9679191|reactome:R-HSA-9732724|refseq:NP_000407.1|panther:PTHR20859(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:lE0NJNR3ItPnoiugDg2ZJno2okg9606	intact-crc:54B48C08D680680C|rigid:oSGeep+bfsfvl+b9NvgYnUf3mww	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFP9	uniprotkb:P06213	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	intact:EBI-475899|uniprotkb:Q17RW0|uniprotkb:Q59H98|uniprotkb:Q9UCB7|uniprotkb:Q9UCB8|uniprotkb:Q9UCB9|ensembl:ENSP00000303830.4	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	psi-mi:insr_human(display_long)|uniprotkb:INSR(gene name)|psi-mi:INSR(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805844|imex:IM-13779-961	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	"panther:PTHR24416(orthology-group)|ensembl:ENSG00000171105.14(gene)|ensembl:ENST00000302850.10(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005899""(insulin receptor complex)|go:""GO:0005901""(caveola)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007612""(learning)|go:""GO:0007613""(memory)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008288""(boss receptor activity)|go:""GO:0008544""(epidermis development)|go:""GO:0008584""(male gonad development)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030238""(male sex determination)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0030325""(adrenal gland development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0031017""(exocrine pancreas development)|go:""GO:0031623""(receptor internalization)|go:""GO:0031994""(insulin-like growth factor I binding)|rcsb pdb:1IR3|go:""GO:0031995""(insulin-like growth factor II binding)|go:""GO:0032148""(activation of protein kinase B activity)|go:""GO:0032590""(dendrite membrane)|go:""GO:0032809""(neuronal cell body membrane)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0043243""(positive regulation of protein-containing complex disassembly)|go:""GO:0043406""(positive regulation of MAP kinase activity)|go:""GO:0043410""(positive regulation of MAPK cascade)|rcsb pdb:1IRK|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0043559""(insulin binding)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045725""(positive regulation of glycogen biosynthetic process)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0045840""(positive regulation of mitotic nuclear division)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048639""(positive regulation of developmental growth)|go:""GO:0051425""(PTB domain binding)|go:""GO:0051446""(positive regulation of meiotic cell cycle)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1990535""(neuron projection maintenance)|go:""GO:2000194""(regulation of female gonad development)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016246(Insulin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036941|interpro:IPR040969|interpro:IPR050122|mint:P06213|rcsb pdb:1GAG|rcsb pdb:1I44|rcsb pdb:1P14|rcsb pdb:1RQQ|rcsb pdb:2AUH|rcsb pdb:2B4S|rcsb pdb:2HR7|rcsb pdb:2MFR|rcsb pdb:2Z8C|rcsb pdb:3BU3|rcsb pdb:3BU5|rcsb pdb:3BU6|rcsb pdb:3EKK|rcsb pdb:3EKN|rcsb pdb:3ETA|rcsb pdb:3W11|rcsb pdb:3W12|rcsb pdb:3W13|rcsb pdb:4IBM|rcsb pdb:4OGA|rcsb pdb:4XLV|rcsb pdb:4XSS|rcsb pdb:4XST|rcsb pdb:4ZXB|rcsb pdb:5E1S|rcsb pdb:5HHW|rcsb pdb:5J3H|rcsb pdb:5KQV|rcsb pdb:5U1M|rcsb pdb:6HN4|rcsb pdb:6HN5|rcsb pdb:6PXV|rcsb pdb:6PXW|rcsb pdb:6SOF|rcsb pdb:6VEP|rcsb pdb:6VEQ|rcsb pdb:7BW7|rcsb pdb:7BW8|rcsb pdb:7BWA|rcsb pdb:7KD6|rcsb pdb:7MQO|rcsb pdb:7MQR|rcsb pdb:7MQS|rcsb pdb:7PG0|rcsb pdb:7PG2|rcsb pdb:7PG3|rcsb pdb:7PG4|rcsb pdb:7PHT|rcsb pdb:7QID|rcsb pdb:7S0Q|rcsb pdb:7S8V|rcsb pdb:7U6D|rcsb pdb:7U6E|rcsb pdb:7YQ3|rcsb pdb:7YQ4|rcsb pdb:7YQ5|rcsb pdb:7YQ6|rcsb pdb:8DWN|rcsb pdb:8GUY|rcsb pdb:8U4B|rcsb pdb:8U4C|rcsb pdb:8U4E|rcsb pdb:8VJB|rcsb pdb:8VJC|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-74752|reactome:R-HSA-77387|refseq:NP_000199.2|refseq:NP_001073285.1|dip:DIP-480N|efo:""Orphanet:2297""|efo:""Orphanet:263458""|efo:""Orphanet:508""|efo:""Orphanet:769"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	rogid:mLKbADp8yGfO+Kic/dzn3VFCZrc9606	intact-crc:0779D09FCDFAE78A|rigid:UvGrF01OkkZn9aTIELK1Dy1hyX0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFP9	uniprotkb:O15397	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	intact:EBI-358808|uniprotkb:B7Z7M3|intact:EBI-28976929|ensembl:ENSP00000256079.4	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805837|imex:IM-13779-959	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	"panther:PTHR10997(orthology-group)|dip:DIP-44186N|efo:""Orphanet:60030""|ensembl:ENSG00000133704.10(gene)|ensembl:ENST00000256079.9(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007165""(signal transduction)|go:""GO:0031267""(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|refseq:NP_006381.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606	intact-crc:E3864F979DFF15FF|rigid:xa6z9h+b+hnHPo/D4h4oaY8R4HU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48551	uniprotkb:Q5NH91	intact:EBI-958408|uniprotkb:A8KAJ4|uniprotkb:Q6FHD7|uniprotkb:D3DSE8|uniprotkb:D3DSE9|uniprotkb:Q15467|ensembl:ENSP00000343957.5|ensembl:ENSP00000508013.1	intact:EBI-2804245|uniprotkb:A0A0G2RMJ8	psi-mi:inar2_human(display_long)|uniprotkb:IFNAR2(gene name)|psi-mi:IFNAR2(display_short)|uniprotkb:IFNARB(gene name synonym)|uniprotkb:Type I interferon receptor 2(gene name synonym)|uniprotkb:IFNABR(gene name synonym)|uniprotkb:Interferon alpha binding protein(gene name synonym)	psi-mi:q5nh91_fratt(display_long)|uniprotkb:sdaA(gene name)|psi-mi:sdaA(display_short)|uniprotkb:FTT_0577(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805858|imex:IM-13779-962	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:431166""|dip:DIP-945N|ensembl:ENSG00000159110.22(gene)|ensembl:ENST00000342136.9(transcript)|ensembl:ENST00000683941.1(transcript)|go:""GO:0004905""(type I interferon receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008269""(JAK pathway signal transduction adaptor activity)|go:""GO:0009615""(response to virus)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0019962""(type I interferon binding)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042018""(interleukin-22 receptor activity)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0098586""(cellular response to virus)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116|interpro:IPR050650|mint:P48551|rcsb pdb:1N6U|rcsb pdb:1N6V|rcsb pdb:2HYM|rcsb pdb:2KZ1|rcsb pdb:2LAG|rcsb pdb:3S8W|rcsb pdb:3S9D|rcsb pdb:3SE3|rcsb pdb:3SE4|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191|reactome:R-HSA-9705671|reactome:R-HSA-9833109|refseq:NP_000865.2|refseq:NP_001276054.1|refseq:NP_001276055.1|refseq:NP_001276057.1|refseq:NP_997467.1|refseq:NP_997468.1|panther:PTHR20859(orthology-group)"	"interpro:IPR004644(Iron-sulphur-dependent L-serine dehydratase single chain form)|interpro:IPR005130(Serine dehydratase alpha chain)|interpro:IPR005131(Serine dehydratase beta chain)|refseq:YP_169601.1|go:""GO:0003941""(L-serine ammonia-lyase activity)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR029009|refseq:WP_003019268.1|interpro:IPR051318"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:n9jPySJ4jlqmT6QgmSlEeNLwUog9606	rogid:rAJJN6zltZpSciqSe5iWZMw1tLg177416	intact-crc:0D6FE3422071E1F9|rigid:/x7lHPFuW0vay7NokvGhZ5ylpFI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEH1	uniprotkb:Q14974	intact:EBI-2796391|uniprotkb:A0A0G2RMG3	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|ensembl:ENSP00000290158.3|ensembl:ENSP00000464042.2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864	psi-mi:q5neh1_fratt(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:FTT_1664(locus name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805872|imex:IM-13779-965	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_170571.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|refseq:WP_003022611.1|interpro:IPR036897|interpro:IPR036914"	"ensembl:ENSG00000108424.11(gene)|ensembl:ENST00000290158.9(transcript)|ensembl:ENST00000583648.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006404""(RNA import into nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0006610""(ribosomal protein import into nucleus)|go:""GO:0007079""(mitotic chromosome movement towards spindle pole)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035580""(specific granule lumen)|go:""GO:0040001""(establishment of mitotic spindle localization)|go:""GO:0042564""(NLS-dependent protein nuclear import complex)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:8GCN|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-68616|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249|reactome:R-HSA-9692916|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|panther:PTHR10527(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/07	rogid:YUFWDuTGDB9kX/RHTWI6fMTHxU0177416	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	intact-crc:C85BF46689D4B243|rigid:yzZUfVv+VMa6wRczYMsRncfQDXk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15131	uniprotkb:Q5NEM9	intact:EBI-540602|uniprotkb:Q86X23|uniprotkb:B2RAI5|ensembl:ENSP00000348704.1|ensembl:ENSP00000357552.1|intact:EBI-22370853	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:ima6_human(display_long)|uniprotkb:Karyopherin subunit alpha-5(gene name synonym)|uniprotkb:KPNA5(gene name)|psi-mi:KPNA5(display_short)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805879|imex:IM-13779-964	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002260.2|refseq:XP_016866328.1|ensembl:ENSG00000196911.12(gene)|ensembl:ENST00000356348.6(transcript)|ensembl:ENST00000368564.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0042564""(NLS-dependent protein nuclear import complex)|go:""GO:0061608""(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O15131|rcsb pdb:4U2X|reactome:R-HSA-1169408|reactome:R-HSA-168276|refseq:XP_016866329.1|dip:DIP-33405N|panther:PTHR23316(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/19	rogid:go2yjKCTn//7ZDypkBtAh9oCLWQ9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:4CAF376CE553DD58|rigid:IDwZ2aShDK0gLBywIZyZGOylESg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI89	uniprotkb:Q8NI35	intact:EBI-2796250	intact:EBI-724390|uniprotkb:O15249|uniprotkb:O43742|uniprotkb:O60833|uniprotkb:Q5VUA5|uniprotkb:Q5VUA6|uniprotkb:Q5VUA7|uniprotkb:Q5VUA8|uniprotkb:Q5VUA9|uniprotkb:Q5VUB0|uniprotkb:Q8WU78|uniprotkb:Q9H3N9|ensembl:ENSP00000360200.2	psi-mi:q5ni89_fratt(display_long)|uniprotkb:lysS(gene name synonym)|uniprotkb:lysU(gene name)|psi-mi:lysU(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0192(locus name)	psi-mi:inadl_human(display_long)|uniprotkb:CIPP(gene name synonym)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:PATJ(gene name)|psi-mi:PATJ(display_short)|uniprotkb:INADL(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805865|imex:IM-13779-963	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|interpro:IPR044136|refseq:YP_169253.1|interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR045864"	"ensembl:ENSG00000132849.22(gene)|ensembl:ENST00000371158.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030054""(cell junction)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035089""(establishment of apical/basal cell polarity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0043296""(apical junction complex)|go:""GO:0045177""(apical part of cell)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120192""(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|interpro:IPR051342|mint:Q8NI35|rcsb pdb:1VF6|rcsb pdb:2D92|rcsb pdb:2DAZ|rcsb pdb:2DB5|rcsb pdb:2DLU|rcsb pdb:2DM8|rcsb pdb:2DMZ|rcsb pdb:2EHR|rcsb pdb:4Q2N|rcsb pdb:6IRD|reactome:R-HSA-420029|reactome:R-HSA-9705677|panther:PTHR19964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4e6LdrlEB4PMi+b0yLmkVagonC4177416	rogid:brzBKZb3r39w13Ds5X/1jB6YMyM9606	intact-crc:8D3F5DB0B06A1FCF|rigid:4CY6Nkkjo5G+l7wyllo7Uv/ih1M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:P31785	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-80475|uniprotkb:Q5FC12|ensembl:ENSP00000363318.3	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:il2rg_human(display_long)|uniprotkb:IL2RG(gene name)|psi-mi:IL2RG(display_short)|uniprotkb:p64(gene name synonym)|uniprotkb:gammaC(gene name synonym)|uniprotkb:Interleukin-2 receptor subunit gamma(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805886|imex:IM-13779-968	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"panther:PTHR23036(orthology-group)|efo:""Orphanet:276""|efo:""Orphanet:39041""|dip:DIP-173N|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|ensembl:ENSG00000147168.14(gene)|ensembl:ENST00000374202.7(transcript)|go:""GO:0002335""(mature B cell differentiation)|go:""GO:0002361""(CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010467""(gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019725""(cellular homeostasis)|go:""GO:0019955""(cytokine binding)|go:""GO:0019976""(interleukin-2 binding)|go:""GO:0030098""(lymphocyte differentiation)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033089""(positive regulation of T cell differentiation in thymus)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0042010""(interleukin-15 receptor activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045579""(positive regulation of B cell differentiation)|go:""GO:0050766""(positive regulation of phagocytosis)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR048648|interpro:IPR053856|rcsb pdb:2B5I|rcsb pdb:2ERJ|rcsb pdb:3BPL|rcsb pdb:3QAZ|rcsb pdb:3QB7|rcsb pdb:4GS7|rcsb pdb:5M5E|rcsb pdb:6OEL|rcsb pdb:7S2R|rcsb pdb:8ENT|rcsb pdb:8EPA|reactome:R-HSA-1266695|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-8983432|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020958|reactome:R-HSA-912526|reactome:R-HSA-9701898|refseq:NP_000197.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:Fz1gJI4Qk1jAguOQqWXbAWUb/8o9606	intact-crc:F0AE32A1BB7F343F|rigid:QN2mKwspasz1FHoieOw/o7bSQGw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH71	uniprotkb:P01857	intact:EBI-2805903	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	psi-mi:q5nh71_fratt(display_long)|uniprotkb:FTT_0598c(locus name)	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805900|imex:IM-13779-969	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001991(""Sodium:dicarboxylate symporter"")|refseq:YP_169621.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015184""(L-cystine transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|interpro:IPR036458"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:c60FGKqyIlANbm2vB4QdnjedWtI177416	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	intact-crc:F97155FB380C5B8F|rigid:4pX3ouzKiZW4oaY3TE2SyhIKa6c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:P25963	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-307386|uniprotkb:B2R8L6|ensembl:ENSP00000216797.6	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:ikba_human(display_long)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805893|imex:IM-13779-966	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"efo:""Orphanet:150""|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:98813""|ensembl:ENSG00000100906.12(gene)|ensembl:ENST00000216797.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007253""(obsolete cytoplasmic sequestering of NF-kappaB)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0010745""(negative regulation of macrophage derived foam cell differentiation)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0045638""(negative regulation of myeloid cell differentiation)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070417""(cellular response to cold)|go:""GO:0070427""(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140313""(molecular sequestering activity)|go:""GO:0140416""(transcription regulator inhibitor activity)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR051070|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9692916|reactome:R-HSA-9860927|refseq:NP_065390.1|dip:DIP-139N|ensembl:ENSP00000216797.6|panther:PTHR46680(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	intact-crc:1E2748ED0BA2344B|rigid:lEauzTorPle1xUhMfvvvG6NYKCQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01877	uniprotkb:Q5NID2	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	intact:EBI-2796292	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805910|imex:IM-13779-967	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	intact-crc:C4C5B28E3A362004|rigid:VjrsU8+Jjeh4h6AlWh3Qkc9AQsk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01877	uniprotkb:Q5NH94	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	intact:EBI-2801000	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	psi-mi:alr_fratt(display_long)|uniprotkb:FTT_0573(locus name)|uniprotkb:alr(gene name)|psi-mi:alr(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805924|imex:IM-13779-970	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"interpro:IPR029066|interpro:IPR000821(Alanine racemase region)|interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR011079(Alanine racemase, C-terminal)|interpro:IPR001608(Alanine racemase, N-terminal)|refseq:YP_169598.1|go:""GO:0005829""(cytosol)|go:""GO:0008784""(alanine racemase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0030632""(D-alanine biosynthetic process)|refseq:WP_003029065.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	rogid:Nn8jh6itSZ6i9H7ABf7r19HanHQ177416	intact-crc:AA75C38E3BED1B9F|rigid:+6ej3BAdgMOtwLl7x9MFLN0FNYc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8G8T7	uniprotkb:P01877	intact:EBI-2796603	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	psi-mi:q8g8t7_fratl(display_long)|uniprotkb:asd(gene name)|psi-mi:asd(display_short)	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805917|imex:IM-13779-972	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004073""(aspartate-semialdehyde dehydrogenase activity)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0009088""(threonine biosynthetic process)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0019877""(diaminopimelate biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_003020169.1|interpro:IPR000319(Aspartate-semialdehyde dehydrogenase, conserved site)|interpro:IPR011534(Aspartate-semialdehyde dehydrogenase, proteobacteria)|interpro:IPR000534(Semialdehyde dehydrogenase, NAD-binding)|interpro:IPR012280(Semialdehyde dehydrogenase, dimerisation region)|rcsb pdb:4WOJ|interpro:IPR036291"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HbI1K+KPeND7CwD3y7jf62tQ4ZA119856	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	intact-crc:A4BCB034061CFFC1|rigid:K1fXe4mc5TB/8h627ZUVZs1NSaA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01877	uniprotkb:Q4VP87	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	intact:EBI-2796861	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	psi-mi:q4vp87_fratl(display_long)|uniprotkb:FTT0445(orf name)|uniprotkb:uup(gene name)|psi-mi:uup(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805938|imex:IM-13779-971	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"go:""GO:0005524""(ATP binding)|interpro:IPR027417|interpro:IPR032781|interpro:IPR051309"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	rogid:+Qbmzj8eW72wb4LBUxcHkhpPQRE119856	intact-crc:14CFB7CB4A0841C4|rigid:CtaUoeN6ppAafxT4L7FymD11Jts	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NG93	uniprotkb:P01877	intact:EBI-2797241|uniprotkb:A0A0G2RNP8	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	psi-mi:q5ng93_fratt(display_long)|uniprotkb:xthA(gene name)|psi-mi:xthA(display_short)|uniprotkb:FTT_0959c(locus name)	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805931|imex:IM-13779-973	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003906""(""DNA-(apurinic or apyrimidinic site) endonuclease activity"")|go:""GO:0006284""(base-excision repair)|go:""GO:0008081""(phosphoric diester hydrolase activity)|go:""GO:0008311""(double-stranded DNA 3'-5' DNA exonuclease activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR004808(Exodeoxyribonuclease III xth)|refseq:YP_169949.1|refseq:WP_003021031.1|interpro:IPR036691"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UmV6e4+lqB1TTnnIHyqtaomo34c177416	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	intact-crc:D98C1C8E3A7BE480|rigid:3R0M5iP/r3v39GD2hdsQQmlVEvM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHX0	uniprotkb:P01877	intact:EBI-2799263	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	psi-mi:efg_fratt(display_long)|uniprotkb:FTT_0323(locus name)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805945|imex:IM-13779-974	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169372.1|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR031157|refseq:WP_003028885.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|interpro:IPR047872"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hULyXsLqQVOFqECbDOTlNV2kzrY177416	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	intact-crc:2F44C38E3A89855B|rigid:u+BHRmfGchXSLdvI2Yinwj8xAGw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P60842	uniprotkb:Q5NFV6	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831.8	intact:EBI-2797055|uniprotkb:A0A0G2RM43	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:q5nfv6_fratt(display_long)|uniprotkb:rpoH(gene name)|psi-mi:rpoH(display_short)|uniprotkb:RNA polymerase sigma-32 factor(gene name synonym)|uniprotkb:FTT_1112c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805980|imex:IM-13779-978	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001407.1|panther:PTHR24031(orthology-group)|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960.16(gene)|ensembl:ENST00000293831.13(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097165""(nuclear stress granule)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|rcsb pdb:7PPZ|rcsb pdb:7PQ0|rcsb pdb:8HUJ|rcsb pdb:8OZ0|rcsb pdb:8XXN|rcsb pdb:9AVR|rcsb pdb:9BLN|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865"	"go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0009408""(response to heat)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0016987""(sigma factor activity)|refseq:YP_170086.1|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012759(RNA polymerase sigma factor RpoH, proteobacteria)|refseq:WP_003021274.1|interpro:IPR050813"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	rogid:TUiRpVCoti/MNhIPmxh1x7nUv4Q177416	intact-crc:18D410D9026992B4|rigid:sNroR2PpXQltxaEVJxzf9hh1S+Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14240	uniprotkb:Q5NGN2	intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381.5	intact:EBI-2803463|uniprotkb:A0A0G2RMU1	psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:q5ngn2_fratt(display_long)|uniprotkb:ans(gene name)|psi-mi:ans(display_short)|uniprotkb:FTT_0803(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805973|imex:IM-13779-976	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24031(orthology-group)|efo:""Orphanet:528084""|ensembl:ENSG00000156976.17(gene)|ensembl:ENST00000323963.10(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1900260""(negative regulation of RNA-dependent RNA polymerase activity)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865|refseq:NP_001958.2"	"interpro:IPR000246(Peptidase T2, asparaginase 2)|refseq:YP_169810.1|go:""GO:0004067""(asparaginase activity)|interpro:IPR029055|refseq:WP_003020718.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/30	rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606	rogid:Seck/e2N8Okq24qR9dX3A4maVVU177416	intact-crc:918CFB163DA08BC4|rigid:/RGka7Ts5wLg0crdtkuXJoj8Nlc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIA8	uniprotkb:O60573	intact:EBI-2800376	intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416.3	psi-mi:rf1_fratt(display_long)|uniprotkb:FTT_0168(locus name)|uniprotkb:prfA(gene name)|psi-mi:prfA(display_short)	psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805966|imex:IM-13779-977	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004373(Peptide chain release factor 1)|refseq:YP_169234.1|go:""GO:0005737""(cytoplasm)|go:""GO:0016149""(translation release factor activity, codon specific)|refseq:WP_003019960.1|interpro:IPR050057|interpro:IPR045853"	"refseq:NP_004837.1|ensembl:ENSG00000135930.15(gene)|ensembl:ENST00000258416.8(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0098808""(mRNA cap binding)|interpro:IPR001040(""Eukaryotic translation initiation factor 4E (eIF-4E)"")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|dip:DIP-32578N|refseq:NP_001263265.1|panther:PTHR11960(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/30	rogid:6lZUlvLNR06AfQiCbfXKwNEmHoE177416	rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606	intact-crc:BB66D7614FB1E1CD|rigid:cAJTDkAy3Web65E/bGCmpaCGC/c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGF6	uniprotkb:P40305	intact:EBI-2798182|uniprotkb:A0A0G2RN31	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	psi-mi:q5ngf6_fratt(display_long)|uniprotkb:FTT_0889c(locus name)	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805959|imex:IM-13779-975	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR055160|interpro:IPR012902(Prepilin-type cleavage/methylation, N-terminal)|refseq:YP_169886.1|rcsb pdb:3SOJ|refseq:WP_003020879.1|interpro:IPR045584|interpro:IPR050470"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:j8Bn0IlLtg5yjAogbk3Of9TM0do177416	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	intact-crc:A1DE9FEAA7DA86FC|rigid:4BilOcz2Qf09fvw8dMlxzTRpozQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P41091	uniprotkb:Q5NGZ7	intact:EBI-1054228|uniprotkb:B5BTZ4|intact:EBI-11602611|uniprotkb:A0A024RBY4|uniprotkb:A8K2Y2|uniprotkb:B2R5N2|uniprotkb:Q53HK3|ensembl:ENSP00000253039.4	intact:EBI-2801271|uniprotkb:A0A0G2RN55	psi-mi:if2g_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit gamma X(gene name synonym)|uniprotkb:EIF2S3(gene name)|psi-mi:EIF2S3(display_short)|uniprotkb:EIF2G(gene name synonym)	psi-mi:q5ngz7_fratt(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:FTT_0679c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2805987|imex:IM-13779-979	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:85282""|ensembl:ENSG00000130741.11(gene)|ensembl:ENST00000253039.9(transcript)|go:""GO:0001731""(formation of translation preinitiation complex)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005850""(eukaryotic translation initiation factor 2 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990856""(methionyl-initiator methionine tRNA binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|interpro:IPR050543|mint:P41091|rcsb pdb:6FEC|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|rcsb pdb:7F66|rcsb pdb:7F67|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PHD|rcsb pdb:8PHV|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PPL|rcsb pdb:8QZZ|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|reactome:R-HSA-9833482|reactome:R-HSA-9840373|refseq:NP_001406.1|panther:PTHR42854(orthology-group)"	"interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|refseq:YP_169695.1|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0043023""(ribosomal large subunit binding)|interpro:IPR041706|interpro:IPR004095(TGS)|refseq:WP_003020468.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6uBTiGTvEKMfS0NqkKGIaSR61j89606	rogid:tfY1+moC9oziAj7eZ4ePmeICDRQ177416	intact-crc:91340C2952C8B8DD|rigid:WYAPTNqSH4Xoj0xJprS6F1JB7f8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75874	uniprotkb:Q5NHY6	intact:EBI-715695|uniprotkb:Q567U4|uniprotkb:Q6FHQ6|uniprotkb:Q7Z3V0|uniprotkb:Q93090|uniprotkb:Q9NTJ9|uniprotkb:Q9UKW8|ensembl:ENSP00000260985.2|ensembl:ENSP00000390265.1|ensembl:ENSP00000410513.1	intact:EBI-2796153	"psi-mi:idhc_human(display_long)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:""NADP(+)-specific ICDH""(gene name synonym)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:PICD(gene name synonym)|uniprotkb:IDPc(gene name synonym)"	psi-mi:sye_fratt(display_long)|uniprotkb:gltX(gene name)|psi-mi:gltX(display_short)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0307(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806021|imex:IM-13779-982	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-59311N|ensembl:ENSG00000138413.14(gene)|ensembl:ENST00000345146.7(transcript)|ensembl:ENST00000415913.5(transcript)|ensembl:ENST00000446179.5(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004450""(""isocitrate dehydrogenase (NADP+) activity"")|rcsb pdb:1T0L|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006097""(glyoxylate cycle)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006102""(isocitrate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0006739""(NADP metabolic process)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0008585""(female gonad development)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|go:""GO:0060696""(regulation of phospholipid catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071071""(regulation of phospholipid biosynthetic process)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:O75874|rcsb pdb:1T09|rcsb pdb:3INM|rcsb pdb:3MAP|rcsb pdb:3MAR|rcsb pdb:3MAS|rcsb pdb:4I3K|rcsb pdb:4I3L|rcsb pdb:4KZO|rcsb pdb:4L03|rcsb pdb:4L04|rcsb pdb:4L06|rcsb pdb:4UMX|rcsb pdb:4UMY|rcsb pdb:4XRX|rcsb pdb:4XS3|rcsb pdb:5DE1|rcsb pdb:5GIR|rcsb pdb:5K10|rcsb pdb:5K11|rcsb pdb:5L57|rcsb pdb:5L58|rcsb pdb:5LGE|rcsb pdb:5SUN|rcsb pdb:5SVF|rcsb pdb:5TQH|rcsb pdb:5YFM|rcsb pdb:5YFN|rcsb pdb:6ADG|rcsb pdb:6B0Z|rcsb pdb:6BKX|rcsb pdb:6BKY|rcsb pdb:6BKZ|rcsb pdb:6BL0|rcsb pdb:6BL1|rcsb pdb:6BL2|rcsb pdb:6IO0|rcsb pdb:6O2Y|rcsb pdb:6O2Z|rcsb pdb:6PAY|rcsb pdb:6Q6F|rcsb pdb:6U4J|rcsb pdb:6VEI|rcsb pdb:6VG0|rcsb pdb:7PJM|rcsb pdb:7PJN|rcsb pdb:8BAY|rcsb pdb:8HB9|rcsb pdb:8T7D|rcsb pdb:8T7N|rcsb pdb:8T7O|rcsb pdb:8VH9|rcsb pdb:8VHA|rcsb pdb:8VHB|rcsb pdb:8VHC|rcsb pdb:8VHD|rcsb pdb:8VHE|reactome:R-HSA-2978092|reactome:R-HSA-389542|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9818025|refseq:NP_001269315.1|refseq:NP_001269316.1|refseq:NP_005887.2|efo:""Orphanet:163634""|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:296""|efo:""Orphanet:86845""|efo:""Orphanet:99646""|panther:PTHR11822(orthology-group)|ensembl:ENSP00000260985.2|ensembl:ENSP00000390265.1|ensembl:ENSP00000410513.1"	"refseq:YP_169356.1|interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004527(Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020058|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:WP_003021625.1|interpro:IPR033910|interpro:IPR045462|interpro:IPR049940|go:""GO:0000049""(tRNA binding)|go:""GO:0004818""(glutamate-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006424""(glutamyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:RFBziMEb70PKCzUCJm2jd40y44M9606	rogid:6DvyR/b9UNDoFX+nMfvtqGvLXt4177416	intact-crc:D18248AF928FFD19|rigid:4iV5WWz1OFFnocVwpQakTplyZqw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BTL4	uniprotkb:Q5NG53	intact:EBI-2806011|uniprotkb:Q03827|uniprotkb:Q2TAZ2|ensembl:ENSP00000292433.2|ensembl:ENSP00000465617.1|ensembl:ENSP00000467294.1	intact:EBI-2799349	psi-mi:ier2_human(display_long)|uniprotkb:ETR101(gene name synonym)|uniprotkb:Protein ETR101(gene name synonym)|uniprotkb:IER2(gene name)|psi-mi:IER2(display_short)|uniprotkb:PIP92(gene name synonym)	psi-mi:syfa_fratt(display_long)|uniprotkb:pheS(gene name)|psi-mi:pheS(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:FTT_1003c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806008|imex:IM-13779-980	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004898.2|ensembl:ENSG00000160888.8(gene)|ensembl:ENST00000292433.4(transcript)|ensembl:ENST00000587885.2(transcript)|ensembl:ENST00000588173.2(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0030182""(neuron differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048870""(cell motility)|go:""GO:0071774""(response to fibroblast growth factor)|interpro:IPR008653(Immediate early response)|panther:PTHR15895(orthology-group)"	"interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR004188(Phenylalanyl-tRNA synthetase, class II, N-terminal)|interpro:IPR022911|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR010978(tRNA-binding arm)|refseq:YP_169989.1|go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004826""(phenylalanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006432""(phenylalanyl-tRNA aminoacylation)|refseq:WP_003021092.1|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ntl1a1hq0CHQg3o6leUHAVrcNFg9606	rogid:Hq8kBVM9QQ3QfPD8XLRkZND+i8Q177416	intact-crc:AB9C9D6FA4A8BD3D|rigid:/SFZW3Yk5cESHhK8oHF2OBXDqeo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HBG6	uniprotkb:Q5NIP6	intact:EBI-2805994|uniprotkb:Q9UF80|uniprotkb:Q9HAT9|uniprotkb:Q53G36|uniprotkb:Q9BTB9|uniprotkb:Q9BTY4|uniprotkb:G3XAB1|uniprotkb:Q9HBG5|ensembl:ENSP00000324005.4|uniprotkb:B3KW53|uniprotkb:B4DEY9|uniprotkb:B4DPW7|uniprotkb:E7EQF4|uniprotkb:E9PDG2|uniprotkb:E9PDX2|uniprotkb:H7C3C0|uniprotkb:Q8TC06|uniprotkb:Q9NV68	intact:EBI-2796567	psi-mi:if122_human(display_long)|uniprotkb:SPG(gene name synonym)|uniprotkb:WDR10(gene name synonym)|uniprotkb:WDR140(gene name synonym)|uniprotkb:WD repeat-containing protein 10(gene name synonym)|uniprotkb:WD repeat-containing protein 140(gene name synonym)|uniprotkb:IFT122(gene name)|psi-mi:IFT122(display_short)	psi-mi:gata_fratt(display_long)|uniprotkb:FTT_0020(locus name)|uniprotkb:gatA(gene name)|psi-mi:gatA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806001|imex:IM-13779-981	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000163913.14(gene)|ensembl:ENST00000348417.7(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0005737""(cytoplasm)|go:""GO:0005929""(cilium)|go:""GO:0010172""(embryonic body morphogenesis)|go:""GO:0016020""(membrane)|go:""GO:0021513""(spinal cord dorsal/ventral patterning)|go:""GO:0030991""(intraciliary transport particle A)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0035115""(embryonic forelimb morphogenesis)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035720""(intraciliary anterograde transport)|go:""GO:0035721""(intraciliary retrograde transport)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042073""(intraciliary transport)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048593""(camera-type eye morphogenesis)|go:""GO:0060173""(limb development)|go:""GO:0060271""(cilium assembly)|go:""GO:0060971""(embryonic heart tube left/right pattern formation)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0072594""(establishment of protein localization to organelle)|go:""GO:0097542""(ciliary tip)|go:""GO:0097730""(non-motile cilium)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR039857|rcsb pdb:8BBE|rcsb pdb:8BBF|rcsb pdb:8BBG|rcsb pdb:8FGW|rcsb pdb:8FH3|reactome:R-HSA-5610787|reactome:R-HSA-5620924|refseq:NP_001267470.1|refseq:NP_001267474.1|refseq:NP_001267475.1|refseq:NP_060732.2|refseq:NP_443711.2|refseq:NP_443715.1|refseq:NP_443716.1|efo:""Orphanet:1515""|efo:""Orphanet:93268""|panther:PTHR12764(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0030956""(""glutamyl-tRNA(Gln) amidotransferase complex"")|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|interpro:IPR000120(Amidase signature enzyme)|interpro:IPR020556|interpro:IPR023631|interpro:IPR004412(""Glutamyl-tRNA(Gln) amidotransferase A subunit"")|refseq:YP_169096.1|refseq:WP_003022862.1|interpro:IPR036928"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+CItPDBES/UTyqgLedVcoHfVCcM9606	rogid:PXaa59Zvn1xzo0G3HrDFgI8WSJg177416	intact-crc:BB77101EE30CD1C0|rigid:JMjVYncxjygzTTT5ZKSNZkWG224	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12891	uniprotkb:Q5NII2	intact:EBI-2806068|uniprotkb:Q9BW29|uniprotkb:O15177|uniprotkb:B3KRZ2|ensembl:ENSP00000350387.4|ensembl:ENSP00000378571.3|ensembl:ENSP00000401853.1|ensembl:ENSP00000406657.1	intact:EBI-2804321|uniprotkb:A0A0G2RQ93	psi-mi:hyal2_human(display_long)|uniprotkb:LUCA2(gene name synonym)|uniprotkb:Hyaluronoglucosaminidase-2(gene name synonym)|uniprotkb:Lung carcinoma protein 2(gene name synonym)|uniprotkb:HYAL2(gene name)|psi-mi:HYAL2(display_short)	psi-mi:q5nii2_fratt(display_long)|uniprotkb:FTT_0086(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806065|imex:IM-13779-984	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000068001.14(gene)|ensembl:ENST00000357750.9(transcript)|ensembl:ENST00000395139.7(transcript)|ensembl:ENST00000442581.1(transcript)|ensembl:ENST00000447092.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001822""(kidney development)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005540""(hyaluronic acid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006027""(glycosaminoglycan catabolic process)|go:""GO:0009615""(response to virus)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019064""(fusion of virus membrane with host plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030294""(receptor signaling protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0033906""(hyaluronoglucuronidase activity)|go:""GO:0035810""(positive regulation of urine volume)|go:""GO:0042117""(monocyte activation)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045121""(membrane raft)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051216""(cartilage development)|go:""GO:0051607""(defense response to virus)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0061099""(negative regulation of protein tyrosine kinase activity)|go:""GO:0070295""(renal water absorption)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071493""(cellular response to UV-B)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018155|reactome:R-HSA-2160916|refseq:NP_003764.3|refseq:NP_149348.2|refseq:XP_005265581.1|refseq:XP_005265582.1|efo:""Orphanet:508476""|panther:PTHR11769(orthology-group)"	"interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR006314(Dyp-type peroxidase)|refseq:YP_169160.1|go:""GO:0004601""(peroxidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0046872""(metal ion binding)|refseq:WP_003019812.1|interpro:IPR048328"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NzGpBZoflXudvd2QPKOWRc2NOyk9606	rogid:+LH1WQceEflVrrfjPoxm4EmXWgc177416	intact-crc:0BCD3E53DC04BF41|rigid:Iqf7Oh3Fql4udjWL3Zm+3XCSIKY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NET3	uniprotkb:Q12891	intact:EBI-2801773	intact:EBI-2806068|uniprotkb:Q9BW29|uniprotkb:O15177|uniprotkb:B3KRZ2|ensembl:ENSP00000350387.4|ensembl:ENSP00000378571.3|ensembl:ENSP00000401853.1|ensembl:ENSP00000406657.1	psi-mi:q5net3_fratt(display_long)|uniprotkb:fadE(gene name)|psi-mi:fadE(display_short)|uniprotkb:FTT_1529(locus name)	psi-mi:hyal2_human(display_long)|uniprotkb:LUCA2(gene name synonym)|uniprotkb:Hyaluronoglucosaminidase-2(gene name synonym)|uniprotkb:Lung carcinoma protein 2(gene name synonym)|uniprotkb:HYAL2(gene name)|psi-mi:HYAL2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806078|imex:IM-13779-986	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR015396(Protein of unknown function DUF1974)|refseq:YP_170459.3|go:""GO:0004466""(long-chain fatty acyl-CoA dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0033539""(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070991""(medium-chain fatty acyl-CoA dehydrogenase activity)|interpro:IPR036250|interpro:IPR037069|interpro:IPR050741|interpro:IPR046373"	"ensembl:ENSG00000068001.14(gene)|ensembl:ENST00000357750.9(transcript)|ensembl:ENST00000395139.7(transcript)|ensembl:ENST00000442581.1(transcript)|ensembl:ENST00000447092.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001822""(kidney development)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005540""(hyaluronic acid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006027""(glycosaminoglycan catabolic process)|go:""GO:0009615""(response to virus)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019064""(fusion of virus membrane with host plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030294""(receptor signaling protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0033906""(hyaluronoglucuronidase activity)|go:""GO:0035810""(positive regulation of urine volume)|go:""GO:0042117""(monocyte activation)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045121""(membrane raft)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051216""(cartilage development)|go:""GO:0051607""(defense response to virus)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0061099""(negative regulation of protein tyrosine kinase activity)|go:""GO:0070295""(renal water absorption)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071493""(cellular response to UV-B)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018155|reactome:R-HSA-2160916|refseq:NP_003764.3|refseq:NP_149348.2|refseq:XP_005265581.1|refseq:XP_005265582.1|efo:""Orphanet:508476""|panther:PTHR11769(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kKeqoKaBPWvIJmVTDMU1BWCVmTc177416	rogid:NzGpBZoflXudvd2QPKOWRc2NOyk9606	intact-crc:FB7E7253DC5E44A2|rigid:5DXeqX38LndleU+dFY4zG7fFEVQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13598	uniprotkb:Q8G8T7	intact:EBI-2806056|uniprotkb:Q14600|ensembl:ENSP00000388666.1|ensembl:ENSP00000392634.2|ensembl:ENSP00000415283.1|ensembl:ENSP00000462579.1|ensembl:ENSP00000464665.1	intact:EBI-2796603	psi-mi:icam2_human(display_long)|uniprotkb:ICAM2(gene name)|psi-mi:ICAM2(display_short)	psi-mi:q8g8t7_fratl(display_long)|uniprotkb:asd(gene name)|psi-mi:asd(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806053|imex:IM-13779-985	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000864.2|refseq:NP_001093256.1|refseq:NP_001093257.1|refseq:NP_001093258.1|refseq:NP_001093259.1|ensembl:ENSG00000108622.11(gene)|ensembl:ENST00000412356.5(transcript)|ensembl:ENST00000418105.5(transcript)|ensembl:ENST00000449662.6(transcript)|ensembl:ENST00000579687.5(transcript)|ensembl:ENST00000579788.6(transcript)|go:""GO:0001931""(uropod)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|go:""GO:0032154""(cleavage furrow)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR003988(Intercellular adhesion molecule)|interpro:IPR013768(Intercellular adhesion molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR047012|mint:P13598|rcsb pdb:1ZXQ|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-5621575|panther:PTHR13771(orthology-group)"	"go:""GO:0004073""(aspartate-semialdehyde dehydrogenase activity)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0009088""(threonine biosynthetic process)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0019877""(diaminopimelate biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_003020169.1|interpro:IPR000319(Aspartate-semialdehyde dehydrogenase, conserved site)|interpro:IPR011534(Aspartate-semialdehyde dehydrogenase, proteobacteria)|interpro:IPR000534(Semialdehyde dehydrogenase, NAD-binding)|interpro:IPR012280(Semialdehyde dehydrogenase, dimerisation region)|rcsb pdb:4WOJ|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:46FxUe9wv2WIelobimN/4k+qSS89606	rogid:HbI1K+KPeND7CwD3y7jf62tQ4ZA119856	intact-crc:F9FC569371D2D75D|rigid:519lj7oNqFN7XhgvCiTthbJv8U0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5TEJ8	uniprotkb:Q5NI96	intact:EBI-2806032|uniprotkb:B4DZT9|uniprotkb:Q9NS90|uniprotkb:Q9BYB6|uniprotkb:Q5TEJ1|uniprotkb:Q68DP4|uniprotkb:A2RTZ3|uniprotkb:Q5TEJ9|uniprotkb:O60560|uniprotkb:Q5TEK1|uniprotkb:B4DZY3|ensembl:ENSP00000363031.3	intact:EBI-2806028	psi-mi:thms2_human(display_long)|uniprotkb:C1orf38(gene name synonym)|uniprotkb:ICB1(gene name synonym)|uniprotkb:Induced by contact to basement membrane 1 protein(gene name synonym)|uniprotkb:Thymocyte-expressed molecule involved in selection protein 2(gene name synonym)|uniprotkb:THEMIS2(gene name)|psi-mi:THEMIS2(display_short)	psi-mi:ddl_fratt(display_long)|uniprotkb:D-Ala-D-Ala ligase(gene name synonym)|uniprotkb:D-alanylalanine synthetase(gene name synonym)|uniprotkb:FTT_0185(locus name)|uniprotkb:ddl(gene name)|psi-mi:ddl(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806046|imex:IM-13779-983	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273042.1|refseq:NP_001273044.1|refseq:NP_001034566.1|refseq:NP_001099026.1|refseq:NP_004839.2|ensembl:ENSG00000130775.16(gene)|ensembl:ENST00000373921.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050864""(regulation of B cell activation)|interpro:IPR025946|interpro:IPR039671|refseq:XP_006711113.1|panther:PTHR15215(orthology-group)"	"refseq:YP_169246.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR000291(D-alanine--D-alanine ligase/VANA/B/C, conserved site)|interpro:IPR005905(D-alanine--D-alanine ligase)|interpro:IPR011095(D-alanine--D-alanine ligase, C-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008716""(D-alanine-D-alanine ligase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0071555""(cell wall organization)|refseq:WP_003027426.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:d3p6WXby4vsV/5OIxCObzfSkoE89606	rogid:Ofh+mb/jW5UTankYJCJcXlF58wA177416	intact-crc:B0D611FE9DE022ED|rigid:xOSD7U6w1UZaMo7CEsAUi1tKdaE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04792	uniprotkb:Q5NEB2	intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|uniprotkb:B2R4N8|ensembl:ENSP00000248553.6	intact:EBI-2798884|uniprotkb:A0A0G2RQ36	psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym)|uniprotkb:Heat shock protein family B member 1(gene name synonym)	psi-mi:q5neb2_fratt(display_long)|uniprotkb:nhaD(gene name)|psi-mi:nhaD(display_short)|uniprotkb:FTT_1728(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806106|imex:IM-13779-990	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106211.11(gene)|ensembl:ENST00000248553.7(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001533""(cornified envelope)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008426""(protein kinase C inhibitor activity)|go:""GO:0009408""(response to heat)|go:""GO:0009615""(response to virus)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042026""(protein refolding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1904115""(axon cytoplasm)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|refseq:NP_001531.1|efo:""Orphanet:139525""|efo:""Orphanet:99940""|dip:DIP-412N|panther:PTHR45640(orthology-group)"	"interpro:IPR004680(Divalent ion symporter)|refseq:YP_170630.1|go:""GO:0006814""(sodium ion transport)|go:""GO:0015297""(antiporter activity)|go:""GO:0016020""(membrane)|refseq:WP_003022705.1|interpro:IPR045016"	"psi-mi:""MI:0469""(intact)"	crc64:1B4DC44A6F6606D5	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606	rogid:dMkzLU8Z52Olqw/ME0r9WHTAxs4177416	intact-crc:5A5FED426DFE9950|rigid:AskVyl0xNXZCWfmvlR/pnajoZE8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43464	uniprotkb:Q5NHE7	intact:EBI-517086|uniprotkb:Q9HBZ4|uniprotkb:Q9P0Y3|uniprotkb:Q9P0Y4|ensembl:ENSP00000258080.3	intact:EBI-2797375	psi-mi:htra2_human(display_long)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)|uniprotkb:HTRA2(gene name)|psi-mi:HTRA2(display_short)|uniprotkb:PRSS25(gene name synonym)|uniprotkb:OMI(gene name synonym)	psi-mi:q5nhe7_fratt(display_long)|uniprotkb:gyrB(gene name)|psi-mi:gyrB(display_short)|uniprotkb:FTT_0510(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806085|imex:IM-13779-987	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2828""|efo:""Orphanet:505208""|ensembl:ENSG00000115317.13(gene)|ensembl:ENST00000258080.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006508""(proteolysis)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007628""(adult walking behavior)|go:""GO:0008233""(peptidase activity)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009635""(response to herbicide)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0012501""(programmed cell death)|go:""GO:0016020""(membrane)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0019742""(pentacyclic triterpenoid metabolic process)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030291""(protein serine/threonine kinase inhibitor activity)|go:""GO:0030900""(forebrain development)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0048666""(neuron development)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:1905090""(negative regulation of type 2 mitophagy)|go:""GO:1905370""(serine-type endopeptidase complex)|go:""GO:1990948""(ubiquitin ligase inhibitor activity)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001241""(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:O43464|rcsb pdb:1LCY|rcsb pdb:2PZD|rcsb pdb:5FHT|rcsb pdb:5M3N|rcsb pdb:5M3O|rcsb pdb:5TNY|rcsb pdb:5TNZ|rcsb pdb:5TO0|rcsb pdb:5TO1|rcsb pdb:5WYN|rcsb pdb:7VGE|rcsb pdb:8AUK|rcsb pdb:8E2K|reactome:R-HSA-9837999|reactome:R-HSA-9841251|refseq:NP_001308656.1|refseq:NP_037379.1|refseq:NP_659540.1|panther:PTHR22939(orthology-group)"	"go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006265""(DNA topological change)|go:""GO:0034335""(DNA negative supercoiling activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR034160|refseq:YP_169545.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011557(DNA gyrase, subunit B)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR006171(TOPRIM)|interpro:IPR036890|interpro:IPR049353|interpro:IPR041423|interpro:IPR000565(DNA topoisomerase, type IIA, subunit B)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IaLYfoH7H9K64U0KrEY7iB1vAfU9606	rogid:ThkiaCkVSV3ry1m8DcM5w6kTEVs177416	intact-crc:68BD88EC2A37092F|rigid:UVqxnwz+d2kzZYSat1kYsJaA35Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04792	uniprotkb:Q5NGE6	intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|uniprotkb:B2R4N8|ensembl:ENSP00000248553.6	intact:EBI-2796264|uniprotkb:A0A0G2RNI3	psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym)|uniprotkb:Heat shock protein family B member 1(gene name synonym)	psi-mi:q5nge6_fratt(display_long)|uniprotkb:prlC(gene name)|psi-mi:prlC(display_short)|uniprotkb:FTT_0899c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806092|imex:IM-13779-989	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106211.11(gene)|ensembl:ENST00000248553.7(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001533""(cornified envelope)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008426""(protein kinase C inhibitor activity)|go:""GO:0009408""(response to heat)|go:""GO:0009615""(response to virus)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042026""(protein refolding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1904115""(axon cytoplasm)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|refseq:NP_001531.1|efo:""Orphanet:139525""|efo:""Orphanet:99940""|dip:DIP-412N|panther:PTHR45640(orthology-group)"	"go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|refseq:YP_169896.1|interpro:IPR024079|refseq:WP_003020904.1|interpro:IPR024077|interpro:IPR045090|interpro:IPR045666|interpro:IPR034005"	"psi-mi:""MI:0469""(intact)"	crc64:1B4DC44A6F6606D5	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606	rogid:iZq1PA9Cyrdilxgx1L5ibpr8DmY177416	intact-crc:2DB20F426C8CF2F0|rigid:UY/gK6LLVFswLrb5GCh4hbRHDMs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04792	uniprotkb:Q5NEB6	intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|uniprotkb:B2R4N8|ensembl:ENSP00000248553.6	intact:EBI-2797029|uniprotkb:A0A0G2RNW9	psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym)|uniprotkb:Heat shock protein family B member 1(gene name synonym)	psi-mi:q5neb6_fratt(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:FTT_1724c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806099|imex:IM-13779-988	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106211.11(gene)|ensembl:ENST00000248553.7(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001533""(cornified envelope)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008426""(protein kinase C inhibitor activity)|go:""GO:0009408""(response to heat)|go:""GO:0009615""(response to virus)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042026""(protein refolding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1904115""(axon cytoplasm)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|refseq:NP_001531.1|efo:""Orphanet:139525""|efo:""Orphanet:99940""|dip:DIP-412N|panther:PTHR45640(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:1990281""(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|refseq:YP_170626.1|refseq:WP_003022695.1|interpro:IPR051906"	"psi-mi:""MI:0469""(intact)"	crc64:1B4DC44A6F6606D5	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606	rogid:rzu9m+ahxwjrbytyPusL6ALCJRw177416	intact-crc:EE5FED426C8D64B5|rigid:jUfVX0Alx54MQlYgZVi3hpioAsE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGC7	uniprotkb:P08107	intact:EBI-2796378|uniprotkb:A0A0G2RMD1	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:q5ngc7_fratt(display_long)|uniprotkb:FTT_0918(locus name)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806123|imex:IM-13779-993	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_169915.1|interpro:IPR021956|refseq:WP_003020942.1	"go:""GO:0042026""(protein refolding)|go:""GO:0006986""(response to unfolded protein)|refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005829""(cytosol)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005739""(mitochondrion)|go:""GO:0016607""(nuclear speck)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0030529""|go:""GO:0005524""(ATP binding)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0090084""(negative regulation of inclusion body assembly)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0031982""(vesicle)|go:""GO:0010467""(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:""GO:0005654""(nucleoplasm)|go:""GO:1900034""(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:""GO:0016235""(aggresome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0001618""(virus receptor activity)|rcsb pdb:4J8F|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0016234""(inclusion body)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0044822""|go:""GO:0047485""(obsolete protein N-terminus binding)|interpro:IPR029048|ensembl:ENST00000375650|go:""GO:0005814""(centriole)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0034605""(cellular response to heat)|go:""GO:0042623""|go:""GO:0060548""(obsolete negative regulation of cell death)|go:""GO:0070370""(cellular heat acclimation)|interpro:IPR029047|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005925""(focal adhesion)|go:""GO:0031397""(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0050821""(protein stabilization)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PY6VBLnYAPBQCnx7Cz0BtZWqzy0177416	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:C00982B176E6597C|rigid:ELmuo0iE9KsnujA2pf383jIHTec	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NSC5	uniprotkb:Q5NFW7	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|ensembl:ENSP00000376162.2|ensembl:ENSP00000439937.1|ensembl:ENSP00000446026.1|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-2800866	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:sya_fratt(display_long)|uniprotkb:alaS(gene name)|psi-mi:alaS(display_short)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1096c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806130|imex:IM-13779-992	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128.19(gene)|ensembl:ENST00000392351.8(transcript)|ensembl:ENST00000539827.5(transcript)|ensembl:ENST00000542541.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0007216""(G protein-coupled glutamate receptor signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030425""(dendrite)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0035256""(G protein-coupled glutamate receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045178""(basal part of cell)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2001256""(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|interpro:IPR045027|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|panther:PTHR10918(orthology-group)"	"refseq:YP_170075.1|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR018162|interpro:IPR018165|interpro:IPR018164|interpro:IPR023033|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004813""(alanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006419""(alanyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:WP_011242268.1|interpro:IPR050058|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:jCXq3A5fOs0cyqLU6IhdKsy5Apg177416	intact-crc:8C1D1315591E5DBC|rigid:HDf/U4k4vmhzdVb2QZhPWbJDXEI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGM8	uniprotkb:P08107	intact:EBI-2806113|uniprotkb:A0A0G2RQ54	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:q5ngm8_fratt(display_long)|uniprotkb:FTT_0807(locus name)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806116|imex:IM-13779-991	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169814.2|interpro:IPR027602|go:""GO:0016020""(membrane)|refseq:WP_003020726.1"	"go:""GO:0042026""(protein refolding)|go:""GO:0006986""(response to unfolded protein)|refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005829""(cytosol)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005739""(mitochondrion)|go:""GO:0016607""(nuclear speck)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0030529""|go:""GO:0005524""(ATP binding)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0090084""(negative regulation of inclusion body assembly)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0031982""(vesicle)|go:""GO:0010467""(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:""GO:0005654""(nucleoplasm)|go:""GO:1900034""(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:""GO:0016235""(aggresome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0001618""(virus receptor activity)|rcsb pdb:4J8F|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0016234""(inclusion body)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0044822""|go:""GO:0047485""(obsolete protein N-terminus binding)|interpro:IPR029048|ensembl:ENST00000375650|go:""GO:0005814""(centriole)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0034605""(cellular response to heat)|go:""GO:0042623""|go:""GO:0060548""(obsolete negative regulation of cell death)|go:""GO:0070370""(cellular heat acclimation)|interpro:IPR029047|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005925""(focal adhesion)|go:""GO:0031397""(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0050821""(protein stabilization)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1Jj5wvpoGC+t0WAf1Hga0FFjBxI177416	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:CBA782B175947321|rigid:h3mwGNfM7Q+ikUjNeD49rHiTJdc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHL7	uniprotkb:O43390	intact:EBI-2797772|uniprotkb:A0A0G2RPP9	intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|uniprotkb:Q9BV64|uniprotkb:Q2L7G6|ensembl:ENSP00000304405.6|ensembl:ENSP00000363741.1|ensembl:ENSP00000489252.1|ensembl:ENSP00000489371.1	psi-mi:ctu_fratt(display_long)|uniprotkb:ctu(gene name)|psi-mi:ctu(display_short)|uniprotkb:Citrulline ureidase(gene name synonym)|uniprotkb:FTT_0435(locus name)	psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806137|imex:IM-13779-994	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0047781""(citrullinase activity)|go:""GO:0050126""(N-carbamoylputrescine amidase activity)|interpro:IPR017755(N-carbamoylputrescine amidase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:YP_169475.1|refseq:WP_003020185.1|interpro:IPR036526|interpro:IPR050345"	"ensembl:ENSG00000125944.22(gene)|ensembl:ENSG00000282958.5(gene)|ensembl:ENST00000302271.11(transcript)|ensembl:ENST00000374612.5(transcript)|ensembl:ENST00000634263.1(transcript)|ensembl:ENST00000634766.2(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006397""(mRNA processing)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034410|interpro:IPR034411|interpro:IPR035979|interpro:IPR041337|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001095868.1|refseq:NP_001284549.1|refseq:NP_005817.1|refseq:XP_005245768.1|refseq:XP_011538773.1|refseq:XP_016855497.1|efo:""Orphanet:662189""|panther:PTHR21245(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FGQpGqKnAJHiDms9N4fD1E7/6NY177416	rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606	intact-crc:8114B2FD1DD1ACAE|rigid:Ruirfuz9DXyE1C6huW3fdAnxAhw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P05204	uniprotkb:Q5NGR3	intact:EBI-1758689|uniprotkb:Q0VGD5|uniprotkb:Q6FGI5|uniprotkb:Q96C64|ensembl:ENSP00000355228.5	intact:EBI-2796275	psi-mi:hmgn2_human(display_long)|uniprotkb:HMGN2(gene name)|psi-mi:HMGN2(display_short)|uniprotkb:HMG17(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2(gene name synonym)	psi-mi:seca_fratt(display_long)|uniprotkb:FTT_0769(locus name)|uniprotkb:secA(gene name)|psi-mi:secA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806162|imex:IM-13779-996	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005508.1|ensembl:ENSG00000198830.13(gene)|ensembl:ENST00000361427.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05204|panther:PTHR23087(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0017038""(protein import)|go:""GO:0031522""(cell envelope Sec protein transport complex)|go:""GO:0043952""(protein transport by the Sec complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0065002""(intracellular protein transmembrane transport)|refseq:YP_169779.1|interpro:IPR004027(SEC-C motif)|interpro:IPR000185(SecA protein)|interpro:IPR020937|interpro:IPR011115(SecA DEAD-like)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR044722|interpro:IPR027417|refseq:WP_011242256.1|interpro:IPR036266|interpro:IPR036670"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:j8Khsp7BUJh0L9SicpVNR8LP6ZU9606	rogid:c80pRjALHg9VjvniwOaxVtBGz4w177416	intact-crc:96078C80FCEC4999|rigid:X+40DqvNT7WOyFyQyq/xI8CoSqA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35914	uniprotkb:Q5NGC7	intact:EBI-721399|uniprotkb:B7UCC6|uniprotkb:D3Y5K7|uniprotkb:Q6IBC0|uniprotkb:Q96FP8|uniprotkb:B4DUP4|ensembl:ENSP00000363614.3	intact:EBI-2796378|uniprotkb:A0A0G2RMD1	psi-mi:hmgcl_human(display_long)|uniprotkb:3-hydroxy-3-methylglutarate-CoA lyase(gene name synonym)|uniprotkb:HMGCL(gene name)|psi-mi:HMGCL(display_short)	psi-mi:q5ngc7_fratt(display_long)|uniprotkb:FTT_0918(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806169|imex:IM-13779-998	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:20""|ensembl:ENSG00000117305.15(gene)|ensembl:ENST00000374490.8(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004419""(hydroxymethylglutaryl-CoA lyase activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006552""(L-leucine catabolic process)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0030145""(manganese ion binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0046951""(ketone body biosynthetic process)|interpro:IPR000138(Hydroxymethylglutaryl-CoA lyase, active site)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR043594|mint:P35914|rcsb pdb:2CW6|rcsb pdb:3MP3|rcsb pdb:3MP4|rcsb pdb:3MP5|reactome:R-HSA-77111|reactome:R-HSA-9033241|refseq:NP_000182.2|refseq:NP_001159531.1|panther:PTHR42738(orthology-group)"	refseq:YP_169915.1|interpro:IPR021956|refseq:WP_003020942.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5MeWxi06/Ygl18C8UpZKlf9tJc09606	rogid:PY6VBLnYAPBQCnx7Cz0BtZWqzy0177416	intact-crc:E431A6EF61ABA2AF|rigid:AYPQEZkzFFyc+ttbky+lDbTrmqE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09601	uniprotkb:Q5NF37	intact:EBI-2806151|ensembl:ENSP00000216117.8	intact:EBI-2798724	psi-mi:hmox1_human(display_long)|uniprotkb:HO(gene name synonym)|uniprotkb:HO1(gene name synonym)|uniprotkb:HMOX1(gene name)|psi-mi:HMOX1(display_short)	psi-mi:syp_fratt(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1412(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806155|imex:IM-13779-997	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100292.18(gene)|ensembl:ENST00000216117.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0002246""(wound healing involved in inflammatory response)|go:""GO:0002686""(negative regulation of leukocyte migration)|go:""GO:0004392""(""heme oxygenase (decyclizing) activity"")|go:""GO:0005198""(structural molecule activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006788""(heme oxidation)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0014806""(smooth muscle hyperplasia)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0019899""(enzyme binding)|go:""GO:0020037""(heme binding)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0034101""(erythrocyte homeostasis)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042167""(heme catabolic process)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048662""(negative regulation of smooth muscle cell proliferation)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0071243""(cellular response to arsenic-containing substance)|go:""GO:0071276""(cellular response to cadmium ion)|go:""GO:0072719""(cellular response to cisplatin)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0110076""(negative regulation of ferroptosis)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903589""(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:P09601|rcsb pdb:1N3U|rcsb pdb:1N45|rcsb pdb:1NI6|rcsb pdb:1OYK|rcsb pdb:1OYL|rcsb pdb:1OZE|rcsb pdb:1OZL|rcsb pdb:1OZR|rcsb pdb:1OZW|rcsb pdb:1S13|rcsb pdb:1S8C|rcsb pdb:1T5P|rcsb pdb:1TWN|rcsb pdb:1TWR|rcsb pdb:1XJZ|rcsb pdb:1XK0|rcsb pdb:1XK1|rcsb pdb:1XK2|rcsb pdb:1XK3|rcsb pdb:3CZY|rcsb pdb:3HOK|rcsb pdb:3K4F|rcsb pdb:3TGM|rcsb pdb:4WD4|rcsb pdb:5BTQ|rcsb pdb:6EHA|reactome:R-HSA-189483|reactome:R-HSA-6785807|reactome:R-HSA-844456|reactome:R-HSA-917937|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-9707564|reactome:R-HSA-9707587|reactome:R-HSA-9707616|reactome:R-HSA-9818027|refseq:NP_002124.1|efo:""Orphanet:562509""|efo:""Orphanet:586""|ensembl:ENSP00000216117.8|panther:PTHR10720(orthology-group)"	"interpro:IPR044140|refseq:YP_170355.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|interpro:IPR033730|refseq:WP_003022224.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR045864|interpro:IPR050062"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Qrwo0mQGREIpHf3DLrvyO6DOLKM9606	rogid:6/QkU5JRWJEBZMwaR9J83no0ffk177416	intact-crc:71CB813912CFB7E0|rigid:NR/DTXW3cy1HPppg3a4wGxpuyEY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFY5	uniprotkb:P31943	intact:EBI-2799103|uniprotkb:A0A0G2RM96	intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168.5|ensembl:ENSP00000377082.4|ensembl:ENSP00000397797.2|ensembl:ENSP00000421695.2|ensembl:ENSP00000424087.2|ensembl:ENSP00000425343.2|ensembl:ENSP00000426518.2|ensembl:ENSP00000429661.2|ensembl:ENSP00000492076.2|ensembl:ENSP00000518308.1|ensembl:ENSP00000518309.1|ensembl:ENSP00000518316.1|ensembl:ENSP00000518317.1|ensembl:ENSP00000518318.1|ensembl:ENSP00000518319.1|ensembl:ENSP00000518321.1	psi-mi:q5nfy5_fratt(display_long)|uniprotkb:FTT_1078c(locus name)	psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806144|imex:IM-13779-995	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003021212.1	"efo:""Orphanet:662207""|ensembl:ENSG00000169045.19(gene)|ensembl:ENSG00000284254.4(gene)|ensembl:ENST00000356731.9(transcript)|ensembl:ENST00000393432.9(transcript)|ensembl:ENST00000442819.6(transcript)|ensembl:ENST00000505811.6(transcript)|ensembl:ENST00000513225.6(transcript)|ensembl:ENST00000515158.6(transcript)|ensembl:ENST00000515714.6(transcript)|ensembl:ENST00000521116.6(transcript)|ensembl:ENST00000638505.3(transcript)|ensembl:ENST00000710500.1(transcript)|ensembl:ENST00000710502.1(transcript)|ensembl:ENST00000710510.1(transcript)|ensembl:ENST00000710511.1(transcript)|ensembl:ENST00000710512.1(transcript)|ensembl:ENST00000710513.1(transcript)|ensembl:ENST00000710515.1(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|interpro:IPR050666|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|rcsb pdb:7ZUG|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001244222.1|refseq:NP_005511.1|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1|panther:PTHR13976(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZCh5UU3BrwGnp/Qxno/CBNEc368177416	rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606	intact-crc:0A77FB150628001A|rigid:QKYY0iO18mXth+S8LfVp+ZidBtI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09429	uniprotkb:Q5NIJ3	intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040.4|ensembl:ENSP00000345347.5|ensembl:ENSP00000382417.1|ensembl:ENSP00000384678.1	intact:EBI-2798422|uniprotkb:A0A0G2RM06	psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym)	psi-mi:q5nij3_fratt(display_long)|uniprotkb:sdhA(gene name)|psi-mi:sdhA(display_short)|uniprotkb:FTT_0074(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806176|imex:IM-13779-999	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002119.1|panther:PTHR48112(orthology-group)|ensembl:ENSG00000189403.15(gene)|ensembl:ENST00000339872.8(transcript)|ensembl:ENST00000341423.10(transcript)|ensembl:ENST00000399494.5(transcript)|ensembl:ENST00000405805.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000400""(four-way junction DNA binding)|go:""GO:0000405""(bubble DNA binding)|go:""GO:0000793""(condensed chromosome)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001773""(myeloid dendritic cell activation)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0002407""(dendritic cell chemotaxis)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|interpro:IPR036910|go:""GO:0002643""(regulation of tolerance induction)|go:""GO:0002840""(regulation of T cell mediated immune response to tumor cell)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006265""(DNA topological change)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006310""(DNA recombination)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006914""(autophagy)|go:""GO:0006954""(inflammatory response)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0008301""(DNA binding, bending)|go:""GO:0009986""(cell surface)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016829""(lyase activity)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0017055""(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:""GO:0019958""(C-X-C chemokine binding)|go:""GO:0031175""(neuron projection development)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032072""(regulation of restriction endodeoxyribonuclease activity)|go:""GO:0032392""(DNA geometric change)|go:""GO:0032425""(positive regulation of mismatch repair)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032732""(positive regulation of interleukin-1 production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033151""(""V(D)J recombination"")|go:""GO:0034165""(positive regulation of toll-like receptor 9 signaling pathway)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035711""(T-helper 1 cell activation)|go:""GO:0035868""(alphav-beta3 integrin-HMGB1 complex)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0043371""(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0045063""(T-helper 1 cell differentiation)|go:""GO:0045087""(innate immune response)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050786""(RAGE receptor binding)|go:""GO:0051106""(obsolete positive regulation of DNA ligation)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|go:""GO:0097100""(supercoiled DNA binding)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1905564""(positive regulation of vascular endothelial cell proliferation)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000426""(negative regulation of apoptotic cell clearance)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001200""(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR050342|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|rcsb pdb:8I9M|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_001300821.1|refseq:NP_001300822.1|dip:DIP-24195N"	"go:""GO:0005886""(plasma membrane)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0008177""(""succinate dehydrogenase (quinone) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0009061""(anaerobic respiration)|go:""GO:0022900""(electron transport chain)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|refseq:YP_169149.1|interpro:IPR027477|refseq:WP_003019788.1|interpro:IPR036188|interpro:IPR037099|interpro:IPR030664"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606	rogid:sDR33MuGlwHfY9HuZdMhwuYSZI8177416	intact-crc:1342534C5FA29EE0|rigid:XspNJRmU32agsEmOlRusKoHjdLM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHH6	uniprotkb:Q16534	intact:EBI-2806214|uniprotkb:A0A0G2RPE7	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	psi-mi:q5nhh6_fratt(display_long)|uniprotkb:recJ(gene name)|psi-mi:recJ(display_short)|uniprotkb:FTT_0478c(locus name)	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806211|imex:IM-13779-1003	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051673|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|refseq:YP_169516.1|interpro:IPR038763|go:""GO:0003676""(nucleic acid binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0008409""(5'-3' exonuclease activity)|refseq:WP_003020281.1|interpro:IPR041122|interpro:IPR001667(Phosphoesterase, RecJ-like)"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zEo7VN9F+Dfgb0ejJ99E6n+zMUc177416	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	intact-crc:02FA0CD3FFE848F8|rigid:Ef/LLTftwcnu9rDzCLv5JPgpvNI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFN3	uniprotkb:Q16534	intact:EBI-2799271|uniprotkb:A0A0G2RMM7	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	psi-mi:q5nfn3_fratt(display_long)|uniprotkb:sbcB(gene name)|psi-mi:sbcB(display_short)|uniprotkb:FTT_1200c(locus name)	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806222|imex:IM-13779-1001	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023607|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:YP_170159.1|interpro:IPR034747|interpro:IPR034748|go:""GO:0003677""(DNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0008310""(single-stranded DNA 3'-5' DNA exonuclease activity)|go:""GO:0045004""(DNA replication proofreading)|go:""GO:0046872""(metal ion binding)|refseq:WP_003021452.1|interpro:IPR013620(Exonuclease C-terminal)|interpro:IPR036397"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mZbdpZ1MtY92QBknO89wpvreVGg177416	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	intact-crc:7CF8A2D3FEC6834A|rigid:bViVcNWpU6Gbtf//yCQR8zLPwlA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHX0	uniprotkb:Q96RW7	intact:EBI-2799263	intact:EBI-2806183|uniprotkb:Q96DN8|uniprotkb:Q5TYR7|uniprotkb:Q96DN3|uniprotkb:Q96SC3|uniprotkb:A6NGE3|ensembl:ENSP00000271588.4	psi-mi:efg_fratt(display_long)|uniprotkb:FTT_0323(locus name)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)	psi-mi:hmcn1_human(display_long)|uniprotkb:FIBL6(gene name synonym)|uniprotkb:Fibulin-6(gene name synonym)|uniprotkb:HMCN1(gene name)|psi-mi:HMCN1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806197|imex:IM-13779-1002	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169372.1|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR031157|refseq:WP_003028885.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|interpro:IPR047872"	"refseq:NP_114141.2|refseq:XP_011508340.1|ensembl:ENSG00000143341.12(gene)|ensembl:ENST00000271588.9(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005737""(cytoplasm)|go:""GO:0005912""(adherens junction)|go:""GO:0005927""(muscle tendon junction)|go:""GO:0005938""(cell cortex)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007601""(visual perception)|go:""GO:0009617""(response to bacterium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0051301""(cell division)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071711""(basement membrane organization)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018097|interpro:IPR026823|interpro:IPR036179|interpro:IPR036383|interpro:IPR036465|interpro:IPR049883|interpro:IPR050958|panther:PTHR23277(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hULyXsLqQVOFqECbDOTlNV2kzrY177416	rogid:hybxCgCN8p6aJ6LoTgeKIfTQzYA9606	intact-crc:D1F4A1C1F57C4AD7|rigid:X2NF2zzTnN56qBRigR4D5itLIrw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NG53	uniprotkb:Q16534	intact:EBI-2799349	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	psi-mi:syfa_fratt(display_long)|uniprotkb:pheS(gene name)|psi-mi:pheS(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:FTT_1003c(locus name)	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806204|imex:IM-13779-1000	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR004188(Phenylalanyl-tRNA synthetase, class II, N-terminal)|interpro:IPR022911|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR010978(tRNA-binding arm)|refseq:YP_169989.1|go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004826""(phenylalanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006432""(phenylalanyl-tRNA aminoacylation)|refseq:WP_003021092.1|interpro:IPR045864"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Hq8kBVM9QQ3QfPD8XLRkZND+i8Q177416	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	intact-crc:3B6ED3D3FED671C5|rigid:jMmKUiNpcaVG5AFjZ6NgXOLSNiw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHZ0	uniprotkb:P13747	intact:EBI-2797492|uniprotkb:A0A0G2RNH9	intact:EBI-726583|ensembl:ENSP00000365817.4|ensembl:ENSP00000373091.4|ensembl:ENSP00000390707.2|ensembl:ENSP00000397420.2|ensembl:ENSP00000400458.2|ensembl:ENSP00000402694.2|ensembl:ENSP00000409910.2|uniprotkb:Q30169|uniprotkb:Q9BT83|uniprotkb:Q9GIY7|uniprotkb:Q9GIY8|uniprotkb:E2G051|uniprotkb:Q6DU44	psi-mi:q5nhz0_fratt(display_long)|uniprotkb:lldD1(gene name)|psi-mi:lldD1(display_short)|uniprotkb:FTT_0303c(locus name)	psi-mi:hlae_human(display_long)|uniprotkb:MHC class I antigen E(gene name synonym)|uniprotkb:HLA-E(gene name)|psi-mi:HLA-E(display_short)|uniprotkb:HLA-6.2(gene name synonym)|uniprotkb:HLAE(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806246|imex:IM-13779-1007	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0004460""(""L-lactate dehydrogenase (cytochrome) activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0009060""(aerobic respiration)|go:""GO:0010181""(FMN binding)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR012133(Alpha-hydroxy acid dehydrogenase, FMN-dependent)|interpro:IPR000262(FMN-dependent alpha-hydroxy acid dehydrogenase)|interpro:IPR008259(FMN-dependent alpha-hydroxy acid dehydrogenase, active site)|refseq:YP_169352.1|refseq:WP_003014268.1|interpro:IPR037396"	"ensembl:ENSG00000204592.9(gene)|ensembl:ENSG00000206493.7(gene)|ensembl:ENSG00000225201.6(gene)|ensembl:ENSG00000229252.6(gene)|ensembl:ENSG00000230254.7(gene)|ensembl:ENSG00000233904.6(gene)|ensembl:ENSG00000236632.5(gene)|ensembl:ENST00000376630.5(transcript)|ensembl:ENST00000383597.6(transcript)|ensembl:ENST00000415289.4(transcript)|ensembl:ENST00000415649.4(transcript)|ensembl:ENST00000425603.4(transcript)|ensembl:ENST00000427936.4(transcript)|ensembl:ENST00000444683.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001815""(positive regulation of antibody-dependent cellular cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002477""(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0002715""(regulation of natural killer cell mediated immunity)|go:""GO:0002717""(positive regulation of natural killer cell mediated immunity)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032398""(MHC class Ib protein complex)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032759""(positive regulation of TRAIL production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032815""(negative regulation of natural killer cell activation)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0032819""(positive regulation of natural killer cell proliferation)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046703""(natural killer cell lectin-like receptor binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P13747|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1MHE|rcsb pdb:2ESV|rcsb pdb:3AM8|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GL1|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7BH8|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:8QFY|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005507.3|dip:DIP-32N|panther:PTHR16675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y9b4dmq9ggvJh1XsJVqfxVBq9OQ177416	rogid:JhlO0lcqZm7whCQasHSnQdrA5Tk9606	intact-crc:35BF30D3C8D256BC|rigid:vC5Yxf5AL3sJb9C6i7FtYD24Xng	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13747	uniprotkb:Q5NHX0	intact:EBI-726583|ensembl:ENSP00000365817.4|ensembl:ENSP00000373091.4|ensembl:ENSP00000390707.2|ensembl:ENSP00000397420.2|ensembl:ENSP00000400458.2|ensembl:ENSP00000402694.2|ensembl:ENSP00000409910.2|uniprotkb:Q30169|uniprotkb:Q9BT83|uniprotkb:Q9GIY7|uniprotkb:Q9GIY8|uniprotkb:E2G051|uniprotkb:Q6DU44	intact:EBI-2799263	psi-mi:hlae_human(display_long)|uniprotkb:MHC class I antigen E(gene name synonym)|uniprotkb:HLA-E(gene name)|psi-mi:HLA-E(display_short)|uniprotkb:HLA-6.2(gene name synonym)|uniprotkb:HLAE(gene name synonym)	psi-mi:efg_fratt(display_long)|uniprotkb:FTT_0323(locus name)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806253|imex:IM-13779-1005	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204592.9(gene)|ensembl:ENSG00000206493.7(gene)|ensembl:ENSG00000225201.6(gene)|ensembl:ENSG00000229252.6(gene)|ensembl:ENSG00000230254.7(gene)|ensembl:ENSG00000233904.6(gene)|ensembl:ENSG00000236632.5(gene)|ensembl:ENST00000376630.5(transcript)|ensembl:ENST00000383597.6(transcript)|ensembl:ENST00000415289.4(transcript)|ensembl:ENST00000415649.4(transcript)|ensembl:ENST00000425603.4(transcript)|ensembl:ENST00000427936.4(transcript)|ensembl:ENST00000444683.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001815""(positive regulation of antibody-dependent cellular cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002477""(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0002715""(regulation of natural killer cell mediated immunity)|go:""GO:0002717""(positive regulation of natural killer cell mediated immunity)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032398""(MHC class Ib protein complex)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032759""(positive regulation of TRAIL production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032815""(negative regulation of natural killer cell activation)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0032819""(positive regulation of natural killer cell proliferation)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046703""(natural killer cell lectin-like receptor binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P13747|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1MHE|rcsb pdb:2ESV|rcsb pdb:3AM8|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GL1|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7BH8|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:8QFY|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005507.3|dip:DIP-32N|panther:PTHR16675(orthology-group)"	"refseq:YP_169372.1|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR031157|refseq:WP_003028885.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|interpro:IPR047872"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JhlO0lcqZm7whCQasHSnQdrA5Tk9606	rogid:hULyXsLqQVOFqECbDOTlNV2kzrY177416	intact-crc:AF5D30D3C8D2EF42|rigid:sEwhXY9FQp94xHjW76gixdXQo80	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13747	uniprotkb:Q5NI35	intact:EBI-726583|ensembl:ENSP00000365817.4|ensembl:ENSP00000373091.4|ensembl:ENSP00000390707.2|ensembl:ENSP00000397420.2|ensembl:ENSP00000400458.2|ensembl:ENSP00000402694.2|ensembl:ENSP00000409910.2|uniprotkb:Q30169|uniprotkb:Q9BT83|uniprotkb:Q9GIY7|uniprotkb:Q9GIY8|uniprotkb:E2G051|uniprotkb:Q6DU44	intact:EBI-2806239|uniprotkb:A0A0G2RM01	psi-mi:hlae_human(display_long)|uniprotkb:MHC class I antigen E(gene name synonym)|uniprotkb:HLA-E(gene name)|psi-mi:HLA-E(display_short)|uniprotkb:HLA-6.2(gene name synonym)|uniprotkb:HLAE(gene name synonym)	psi-mi:q5ni35_fratt(display_long)|uniprotkb:FTT_0255c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806236|imex:IM-13779-1004	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204592.9(gene)|ensembl:ENSG00000206493.7(gene)|ensembl:ENSG00000225201.6(gene)|ensembl:ENSG00000229252.6(gene)|ensembl:ENSG00000230254.7(gene)|ensembl:ENSG00000233904.6(gene)|ensembl:ENSG00000236632.5(gene)|ensembl:ENST00000376630.5(transcript)|ensembl:ENST00000383597.6(transcript)|ensembl:ENST00000415289.4(transcript)|ensembl:ENST00000415649.4(transcript)|ensembl:ENST00000425603.4(transcript)|ensembl:ENST00000427936.4(transcript)|ensembl:ENST00000444683.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001815""(positive regulation of antibody-dependent cellular cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002477""(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0002715""(regulation of natural killer cell mediated immunity)|go:""GO:0002717""(positive regulation of natural killer cell mediated immunity)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032398""(MHC class Ib protein complex)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032759""(positive regulation of TRAIL production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032815""(negative regulation of natural killer cell activation)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0032819""(positive regulation of natural killer cell proliferation)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046703""(natural killer cell lectin-like receptor binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P13747|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1MHE|rcsb pdb:2ESV|rcsb pdb:3AM8|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GL1|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7BH8|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:8QFY|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005507.3|dip:DIP-32N|panther:PTHR16675(orthology-group)"	refseq:WP_003021741.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JhlO0lcqZm7whCQasHSnQdrA5Tk9606	rogid:F3RJgLgthy18D0NNHEg8O1eMGBY177416	intact-crc:DADB41D3C9E8D0A6|rigid:RYRuEWGC4qREpGj1XomFrx2ocpg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04233	uniprotkb:Q5NID2	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-2796292	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806260|imex:IM-13779-1008	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	intact-crc:B39F28D720C835A7|rigid:Rqmpr1FQM6+bFwm3ZEcjtwdIfkM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16534	uniprotkb:Q5NF29	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	intact:EBI-2799464|uniprotkb:A0A0G2RM05	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	psi-mi:q5nf29_fratt(display_long)|uniprotkb:FTT_1420(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806229|imex:IM-13779-1006	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	refseq:YP_170363.1|refseq:WP_003022236.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	rogid:9mgAlzt6rxc4WD6OJAXEfdkNiOY177416	intact-crc:A3E4A2D3FC89E25C|rigid:z5eMManb/VXVMvvAMZlqhY58jNc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04233	uniprotkb:Q5NEM9	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806295|imex:IM-13779-1013	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:5BF864D722C87777|rigid:HM2PPrtR7vQ1Y9Uh474hzSCqrEg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04233	uniprotkb:Q5NGC3	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-2799367	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:rlmkl_fratt(display_long)|uniprotkb:FTT_0923(locus name)|uniprotkb:rlmL(gene name)|psi-mi:rlmL(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806274|imex:IM-13779-1011	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"interpro:IPR029063|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR000241(Putative RNA methylase)|interpro:IPR017244(S-adenosyl-L-dependent RNA methyltransferase, bacteria, predicted)|interpro:IPR019614|interpro:IPR004114(THUMP)|refseq:YP_169919.1|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0052915""(""23S rRNA (guanine(2445)-N(2))-methyltransferase activity"")|go:""GO:0070043""(""rRNA (guanine-N7-)-methyltransferase activity"")|refseq:WP_003020954.1|interpro:IPR053943|interpro:IPR054170"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:sWSyt1AaFWM8rwCbDjRuj4j1vDM177416	intact-crc:34EC86D720955F0F|rigid:q0d4neEz61Ie96jaJ59oXq3Djws	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI89	uniprotkb:P04233	intact:EBI-2796250	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:q5ni89_fratt(display_long)|uniprotkb:lysS(gene name synonym)|uniprotkb:lysU(gene name)|psi-mi:lysU(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0192(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806267|imex:IM-13779-1009	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|interpro:IPR044136|refseq:YP_169253.1|interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR045864"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4e6LdrlEB4PMi+b0yLmkVagonC4177416	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:2D8328D722DBABC8|rigid:H6LCZ82k2PYZSVWCIkb7ou6+aa0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04233	uniprotkb:Q5NEU6	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-2799541|uniprotkb:A0A0G2RNM1	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:q5neu6_fratt(display_long)|uniprotkb:dnaJ2(gene name)|psi-mi:dnaJ2(display_short)|uniprotkb:FTT_1512c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806281|imex:IM-13779-1010	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|refseq:YP_170446.1|go:""GO:0005737""(cytoplasm)|go:""GO:0042026""(protein refolding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|refseq:WP_003022390.1|interpro:IPR036869"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:vfCNiJP7u4fjKjv/1B6pZtA2dug177416	intact-crc:886064D721BE58DE|rigid:Pf6qsco2Z/NbpYtYpWacTp5H0VM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NES9	uniprotkb:P04233	intact:EBI-2799997|uniprotkb:A0A0G2RNU2	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:q5nes9_fratt(display_long)|uniprotkb:FTT_1534c(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806288|imex:IM-13779-1012	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|refseq:YP_170463.1|go:""GO:0009435""(NAD biosynthetic process)|go:""GO:0047280""(nicotinamide phosphoribosyltransferase activity)|refseq:WP_003018116.1|interpro:IPR036068|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR041525|interpro:IPR041529"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0+HtF7EvtGUcHmfq6JdVWnUFZs8177416	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:384664D722CE9578|rigid:vT9daHXUyhFoWZg8lpUIuRz4lTA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04233	uniprotkb:Q5NEB4	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-2797653|uniprotkb:A0A0G2RPR1	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:q5neb4_fratt(display_long)|uniprotkb:yegQ(gene name)|psi-mi:yegQ(display_short)|uniprotkb:FTT_1726(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806302|imex:IM-13779-1014	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"interpro:IPR001539(Peptidase U32)|refseq:YP_170628.1|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|interpro:IPR032525|refseq:WP_003022701.1|interpro:IPR051454"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:V8v+igazfnHs0EcKm43UGRWNmrY177416	intact-crc:9F2764D72103FF27|rigid:1eVmlKmA2A3iRKOBWRP9t3mfhiw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID9	uniprotkb:P04233	intact:EBI-2798201	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:eftu_fratt(display_long)|uniprotkb:FTT_0137(locus name)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806320|imex:IM-13779-1015	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0097216""(guanosine tetraphosphate binding)|refseq:YP_169203.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR033720|interpro:IPR031157|refseq:WP_003028672.1|interpro:IPR041709|interpro:IPR050055"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h5xJZCtwL77bt8cg/p85MmX1c+E177416	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:A89F28D722CACFE7|rigid:K7m5hQyZ/JcqvKoQfbIF50/poJw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q30201	uniprotkb:Q5NGX7	intact:EBI-1028850|uniprotkb:O75929|uniprotkb:O75930|uniprotkb:O75931|uniprotkb:Q17RT0|uniprotkb:Q96KU5|uniprotkb:Q96KU7|uniprotkb:Q96KU8|uniprotkb:Q9HC64|uniprotkb:Q9HC68|uniprotkb:Q9HC70|uniprotkb:Q9HC83|uniprotkb:B2CKL0|uniprotkb:Q96KU6|ensembl:ENSP00000417404.1	intact:EBI-2801615	psi-mi:hfe_human(display_long)|uniprotkb:HFE(gene name)|psi-mi:HFE(display_short)|uniprotkb:HLAH(gene name synonym)|uniprotkb:HLA-H(gene name synonym)	psi-mi:pnp_fratt(display_long)|uniprotkb:Polynucleotide phosphorylase(gene name synonym)|uniprotkb:FTT_0699(locus name)|uniprotkb:pnp(gene name)|psi-mi:pnp(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806327|imex:IM-13779-1017	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-2737N|efo:""Orphanet:443057""|efo:""Orphanet:443062""|efo:""Orphanet:465508""|efo:""Orphanet:586""|efo:""Orphanet:648581""|ensembl:ENSG00000010704.20(gene)|ensembl:ENST00000357618.10(transcript)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002725""(negative regulation of T cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010039""(response to iron ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0039706""(co-receptor binding)|go:""GO:0042446""(hormone biosynthetic process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045178""(basal part of cell)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0060391""(positive regulation of SMAD protein signal transduction)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0090277""(positive regulation of peptide hormone secretion)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904283""(negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990641""(response to iron ion starvation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000008""(regulation of protein localization to cell surface)|go:""GO:2000059""(negative regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000272""(negative regulation of signaling receptor activity)|go:""GO:2000273""(positive regulation of signaling receptor activity)|go:""GO:2001186""(negative regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:Q30201|rcsb pdb:1A6Z|rcsb pdb:1DE4|reactome:R-HSA-917977|refseq:NP_000401.1|refseq:NP_001287678.1|refseq:NP_620572.1|refseq:NP_620573.1|refseq:NP_620575.1|refseq:NP_620576.1|refseq:NP_620577.1|refseq:NP_620578.1|refseq:NP_620579.1|refseq:NP_620580.1|panther:PTHR16675(orthology-group)"	"refseq:YP_169715.1|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR020568|interpro:IPR027408|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004654""(polyribonucleotide nucleotidyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0006402""(mRNA catabolic process)|refseq:WP_003020501.1|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YKMZhOMDbQmgnBFdI99XH9BqDp09606	rogid:0NGzY8LkmfRcwKNJb6ydU4X1Qxs177416	intact-crc:E090CA15F3B75E90|rigid:jqq86l7lXCVfv/BwV2mITg+uOwI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHT8	uniprotkb:P04233	intact:EBI-2806309	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806313|imex:IM-13779-1016	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:BE5259D72293FF35|rigid:VsRFFA/mjUM40hmvVEVCYmm9T70	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFC4	uniprotkb:P42694	intact:EBI-2797693	intact:EBI-1210654|uniprotkb:I6L9H4|ensembl:ENSP00000351524.5	psi-mi:g6pi_fratt(display_long)|uniprotkb:Phosphoglucose isomerase(gene name synonym)|uniprotkb:Phosphohexose isomerase(gene name synonym)|uniprotkb:FTT_1315c(locus name)|uniprotkb:pgi(gene name)|psi-mi:pgi(display_short)	psi-mi:helz_human(display_long)|uniprotkb:HELZ(gene name)|psi-mi:HELZ(display_short)|uniprotkb:KIAA0054(gene name synonym)|uniprotkb:DRHC(gene name synonym)|uniprotkb:Down-regulated in human cancers protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806334|imex:IM-13779-1018	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004347""(glucose-6-phosphate isomerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0048029""(monosaccharide binding)|go:""GO:0051156""(glucose 6-phosphate metabolic process)|go:""GO:0097367""(carbohydrate derivative binding)|refseq:YP_170268.1|interpro:IPR001672(""Phosphoglucose isomerase (PGI)"")|interpro:IPR023096|interpro:IPR018189|rcsb pdb:3LJK|rcsb pdb:3M5P|rcsb pdb:3Q7I|rcsb pdb:3Q88|refseq:WP_003022047.1|interpro:IPR035476|interpro:IPR035482|interpro:IPR046348"	"refseq:NP_055692.2|ensembl:ENSG00000198265.12(gene)|ensembl:ENST00000358691.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0035194""(regulatory ncRNA-mediated post-transcriptional gene silencing)|go:""GO:0043186""(P granule)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR027417|interpro:IPR036855|interpro:IPR041677|interpro:IPR041679|interpro:IPR045055|interpro:IPR047187|interpro:IPR049569|mint:P42694|dip:DIP-39352N|panther:PTHR10887(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/17	rogid:M23WDnXwv+cfe3kgPC00m5yzQME177416	rogid:q+2P+W7RDRl2CyPhdEsvONGaM0U9606	intact-crc:3438BB17AFA67904|rigid:rhU99XBseSQ2Bz2BfHrPv9fw45Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIF9	uniprotkb:P68871	intact:EBI-2799085|uniprotkb:A0A0G2RQ41	intact:EBI-715554|uniprotkb:P02023|uniprotkb:Q13852|uniprotkb:Q14481|uniprotkb:Q14510|uniprotkb:Q45KT0|uniprotkb:Q6FI08|uniprotkb:Q8IZI1|uniprotkb:Q9BX96|uniprotkb:Q9UCP8|uniprotkb:Q9UCP9|uniprotkb:A4GX73|uniprotkb:B2ZUE0|uniprotkb:Q549N7|uniprotkb:Q6R7N2|uniprotkb:Q9UCD6|ensembl:ENSP00000333994.3|ensembl:ENSP00000494175.1	psi-mi:q5nif9_fratt(display_long)|uniprotkb:Phosphodeoxyribomutase(gene name synonym)|uniprotkb:deoB(gene name)|psi-mi:deoB(display_short)|uniprotkb:FTT_0113(locus name)	psi-mi:hbb_human(display_long)|uniprotkb:Hemoglobin beta chain(gene name synonym)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806341|imex:IM-13779-1020	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR010045(Phosphopentomutase)|interpro:IPR006124(Metalloenzyme)|interpro:IPR024052|refseq:YP_169183.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006015""(5-phosphoribose 1-diphosphate biosynthetic process)|go:""GO:0006018""(2-deoxyribose 1-phosphate catabolic process)|go:""GO:0008973""(phosphopentomutase activity)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0043094""(metabolic compound salvage)|refseq:WP_003019856.1"	"efo:""Orphanet:2132""|efo:""Orphanet:2133""|efo:""Orphanet:231214""|efo:""Orphanet:231222""|efo:""Orphanet:231226""|efo:""Orphanet:231237""|efo:""Orphanet:231242""|efo:""Orphanet:231249""|efo:""Orphanet:232""|efo:""Orphanet:247511""|efo:""Orphanet:251359""|efo:""Orphanet:251365""|efo:""Orphanet:251370""|efo:""Orphanet:251375""|efo:""Orphanet:251380""|efo:""Orphanet:330032""|efo:""Orphanet:330041""|efo:""Orphanet:46532""|efo:""Orphanet:90039""|dip:DIP-35526N|ensembl:ENSG00000244734.4(gene)|ensembl:ENST00000335295.4(transcript)|ensembl:ENST00000647020.1(transcript)|go:""GO:0005344""(oxygen carrier activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005833""(hemoglobin complex)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0015670""(carbon dioxide transport)|go:""GO:0015671""(oxygen transport)|go:""GO:0019825""(oxygen binding)|go:""GO:0020037""(heme binding)|go:""GO:0030185""(nitric oxide transport)|go:""GO:0030492""(hemoglobin binding)|go:""GO:0031721""(hemoglobin alpha binding)|go:""GO:0031838""(haptoglobin-hemoglobin complex)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0043177""(organic acid binding)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070293""(renal absorption)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0072562""(blood microparticle)|go:""GO:0097746""(blood vessel diameter maintenance)|go:""GO:0098869""(cellular oxidant detoxification)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR050056|mint:P68871|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|rcsb pdb:1A3O|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CBL|rcsb pdb:1CBM|rcsb pdb:1CH4|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J3Z|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|rcsb pdb:1XZ2|rcsb pdb:1XZ4|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|rcsb pdb:1Y45|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|rcsb pdb:1YVQ|rcsb pdb:1YVT|rcsb pdb:1YZI|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3HXN|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|rcsb pdb:3W4U|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQG|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4N7N|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:4N8T|rcsb pdb:4NI0|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4ROM|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6FQF|rcsb pdb:6HAL|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:6KAU|rcsb pdb:6KAV|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEU|rcsb pdb:7AEV|rcsb pdb:7CUE|rcsb pdb:7DY3|rcsb pdb:7DY4|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|rcsb pdb:7JY3|rcsb pdb:7K4M|rcsb pdb:7PCF|rcsb pdb:7PCH|rcsb pdb:7PCQ|rcsb pdb:7UD7|rcsb pdb:7UD8|rcsb pdb:7UF6|rcsb pdb:7UF7|rcsb pdb:7UVB|rcsb pdb:7VDE|rcsb pdb:7XGY|rcsb pdb:8DOV|rcsb pdb:8EGI|rcsb pdb:8FDK|rcsb pdb:8FDL|rcsb pdb:8FDM|rcsb pdb:8FDN|rcsb pdb:8VYL|rcsb pdb:8WJ0|rcsb pdb:8WJ1|rcsb pdb:8WJ2|rcsb pdb:8WXZ|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-6798695|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-983231|refseq:NP_000509.1|panther:PTHR11442(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:A5Ci9aiQ72qwd1VqfoGwme/pcM4177416	rogid:Y5tl4dXE3PBfaK/0lROD6QJ4U+c9606	intact-crc:7369E210EE745C9A|rigid:STM/Sf+RefoGjL51YMsH1I25xZk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P69905	uniprotkb:Q5NFZ2	intact:EBI-714680|uniprotkb:P01922|uniprotkb:Q3MIF5|uniprotkb:Q96KF1|uniprotkb:Q9NYR7|uniprotkb:Q1HDT5|uniprotkb:Q53F97|uniprotkb:Q9UCM0|ensembl:ENSP00000251595.6|ensembl:ENSP00000322421.5	intact:EBI-2801836|uniprotkb:A0A0G2RPS8	psi-mi:hba_human(display_long)|uniprotkb:Hemoglobin alpha chain(gene name synonym)|uniprotkb:Alpha-globin(gene name synonym)|uniprotkb:HBA1(gene name)|psi-mi:HBA1(display_short)|uniprotkb:HBA2(gene name)|psi-mi:HBA2(display_short)	psi-mi:q5nfz2_fratt(display_long)|uniprotkb:FTT_1071c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806355|imex:IM-13779-1021	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J3Z|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1SHR|rcsb pdb:1SI4|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|rcsb pdb:1XZ2|rcsb pdb:1XZ4|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y01|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|ensembl:ENSG00000188536.13(gene)|ensembl:ENSG00000206172.8(gene)|ensembl:ENST00000251595.11(transcript)|ensembl:ENST00000320868.9(transcript)|go:""GO:0005344""(oxygen carrier activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005833""(hemoglobin complex)|go:""GO:0015670""(carbon dioxide transport)|go:""GO:0015671""(oxygen transport)|go:""GO:0016020""(membrane)|go:""GO:0019825""(oxygen binding)|go:""GO:0020037""(heme binding)|go:""GO:0030185""(nitric oxide transport)|go:""GO:0031838""(haptoglobin-hemoglobin complex)|go:""GO:0042542""(response to hydrogen peroxide)|rcsb pdb:1Y45|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0043177""(organic acid binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0072562""(blood microparticle)|go:""GO:0098869""(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR050056|mint:P69905|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|rcsb pdb:1A3O|rcsb pdb:1A9W|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FDH|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|rcsb pdb:1YVQ|rcsb pdb:1YVT|rcsb pdb:1YZI|rcsb pdb:1Z8U|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3HXN|rcsb pdb:3IA3|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3OVU|rcsb pdb:4MQG|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S48|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4MQJ|rcsb pdb:4MQK|rcsb pdb:4N7N|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:4N8T|rcsb pdb:4NI0|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4ROM|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6HAL|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:6KAU|rcsb pdb:6KAV|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEU|rcsb pdb:7AEV|rcsb pdb:7CUE|rcsb pdb:7DY3|rcsb pdb:7DY4|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|rcsb pdb:7JY3|rcsb pdb:7K4M|rcsb pdb:8EGI|rcsb pdb:7PCF|rcsb pdb:7PCH|rcsb pdb:7PCQ|rcsb pdb:7QU4|rcsb pdb:7UD7|rcsb pdb:7UD8|rcsb pdb:7UF6|rcsb pdb:7UF7|rcsb pdb:7UVB|rcsb pdb:7VDE|rcsb pdb:7XGY|rcsb pdb:8DOV|rcsb pdb:8FDK|rcsb pdb:8FDL|rcsb pdb:8FDM|rcsb pdb:8FDN|rcsb pdb:8VYL|rcsb pdb:8WJ0|rcsb pdb:8WJ1|rcsb pdb:8WJ2|rcsb pdb:8WXW|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:NP_000508.1|refseq:NP_000549.1|dip:DIP-35199N|efo:""Orphanet:163596""|efo:""Orphanet:247511""|efo:""Orphanet:330041""|efo:""Orphanet:93616""|efo:""Orphanet:98791""|panther:PTHR11442(orthology-group)"	refseq:YP_170050.1|interpro:IPR009899(Antirestriction)|refseq:WP_003021204.1|interpro:IPR041893|interpro:IPR041895	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:M4o0FF1DIrouBdyFXr4UtAlcjZw9606	rogid:+cJBu3VVWBgg4O59NMvb74DE5m0177416	intact-crc:84F3DFE04B68DFF0|rigid:GjnajB4YGweFRZFIWpWYVc2x9f4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8G8T7	uniprotkb:P69905	intact:EBI-2796603	intact:EBI-714680|uniprotkb:P01922|uniprotkb:Q3MIF5|uniprotkb:Q96KF1|uniprotkb:Q9NYR7|uniprotkb:Q1HDT5|uniprotkb:Q53F97|uniprotkb:Q9UCM0|ensembl:ENSP00000251595.6|ensembl:ENSP00000322421.5	psi-mi:q8g8t7_fratl(display_long)|uniprotkb:asd(gene name)|psi-mi:asd(display_short)	psi-mi:hba_human(display_long)|uniprotkb:Hemoglobin alpha chain(gene name synonym)|uniprotkb:Alpha-globin(gene name synonym)|uniprotkb:HBA1(gene name)|psi-mi:HBA1(display_short)|uniprotkb:HBA2(gene name)|psi-mi:HBA2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806348|imex:IM-13779-1019	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004073""(aspartate-semialdehyde dehydrogenase activity)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0009088""(threonine biosynthetic process)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0019877""(diaminopimelate biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_003020169.1|interpro:IPR000319(Aspartate-semialdehyde dehydrogenase, conserved site)|interpro:IPR011534(Aspartate-semialdehyde dehydrogenase, proteobacteria)|interpro:IPR000534(Semialdehyde dehydrogenase, NAD-binding)|interpro:IPR012280(Semialdehyde dehydrogenase, dimerisation region)|rcsb pdb:4WOJ|interpro:IPR036291"	"rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J3Z|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1SHR|rcsb pdb:1SI4|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|rcsb pdb:1XZ2|rcsb pdb:1XZ4|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y01|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|ensembl:ENSG00000188536.13(gene)|ensembl:ENSG00000206172.8(gene)|ensembl:ENST00000251595.11(transcript)|ensembl:ENST00000320868.9(transcript)|go:""GO:0005344""(oxygen carrier activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005833""(hemoglobin complex)|go:""GO:0015670""(carbon dioxide transport)|go:""GO:0015671""(oxygen transport)|go:""GO:0016020""(membrane)|go:""GO:0019825""(oxygen binding)|go:""GO:0020037""(heme binding)|go:""GO:0030185""(nitric oxide transport)|go:""GO:0031838""(haptoglobin-hemoglobin complex)|go:""GO:0042542""(response to hydrogen peroxide)|rcsb pdb:1Y45|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0043177""(organic acid binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0072562""(blood microparticle)|go:""GO:0098869""(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR050056|mint:P69905|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|rcsb pdb:1A3O|rcsb pdb:1A9W|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FDH|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|rcsb pdb:1YVQ|rcsb pdb:1YVT|rcsb pdb:1YZI|rcsb pdb:1Z8U|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3HXN|rcsb pdb:3IA3|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3OVU|rcsb pdb:4MQG|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S48|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4MQJ|rcsb pdb:4MQK|rcsb pdb:4N7N|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:4N8T|rcsb pdb:4NI0|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4ROM|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6HAL|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:6KAU|rcsb pdb:6KAV|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEU|rcsb pdb:7AEV|rcsb pdb:7CUE|rcsb pdb:7DY3|rcsb pdb:7DY4|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|rcsb pdb:7JY3|rcsb pdb:7K4M|rcsb pdb:8EGI|rcsb pdb:7PCF|rcsb pdb:7PCH|rcsb pdb:7PCQ|rcsb pdb:7QU4|rcsb pdb:7UD7|rcsb pdb:7UD8|rcsb pdb:7UF6|rcsb pdb:7UF7|rcsb pdb:7UVB|rcsb pdb:7VDE|rcsb pdb:7XGY|rcsb pdb:8DOV|rcsb pdb:8FDK|rcsb pdb:8FDL|rcsb pdb:8FDM|rcsb pdb:8FDN|rcsb pdb:8VYL|rcsb pdb:8WJ0|rcsb pdb:8WJ1|rcsb pdb:8WJ2|rcsb pdb:8WXW|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:NP_000508.1|refseq:NP_000549.1|dip:DIP-35199N|efo:""Orphanet:163596""|efo:""Orphanet:247511""|efo:""Orphanet:330041""|efo:""Orphanet:93616""|efo:""Orphanet:98791""|panther:PTHR11442(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:HbI1K+KPeND7CwD3y7jf62tQ4ZA119856	rogid:M4o0FF1DIrouBdyFXr4UtAlcjZw9606	intact-crc:83CD025A7744E14B|rigid:MPQunTuj15Uld7QLZciu8VmVndY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFJ2	uniprotkb:O00165	intact:EBI-2801973|uniprotkb:A0A0G2RP12	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	psi-mi:q5nfj2_fratt(display_long)|uniprotkb:FTT_1242(locus name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806394|imex:IM-13779-1024	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_170200.1|refseq:WP_003021546.1	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:2TebkELetBwT7JBLunOX5Gxqzdk177416	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	intact-crc:9B278A54C99EFECA|rigid:VNHrDU32RlZ3wdxQBBxodJjWEKY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01911	uniprotkb:Q5NGV7	intact:EBI-1033104|uniprotkb:O19717|uniprotkb:O19739|uniprotkb:P13759|uniprotkb:Q29875|uniprotkb:Q30145|uniprotkb:Q9GIX9|uniprotkb:Q9GIY4|uniprotkb:Q9MY13|uniprotkb:Q9XRY5|ensembl:ENSP00000353099.5|uniprotkb:A0MWF2|uniprotkb:A0N0W1|uniprotkb:A2ICT1|uniprotkb:A2TGX3|uniprotkb:A4F5N0|uniprotkb:A4ZXA5|uniprotkb:A4ZXA6|uniprotkb:A4ZY86|uniprotkb:A5H000|uniprotkb:A5HKN8|uniprotkb:A7DZP9|uniprotkb:A7LA26|uniprotkb:A7UHG2|uniprotkb:A7X5B1|uniprotkb:A7X5B7|uniprotkb:A7X5E0|uniprotkb:A7X5E6|uniprotkb:A7X5H8|uniprotkb:A7X5J4|uniprotkb:A7X5K7|uniprotkb:A8K098|uniprotkb:A8YQE9|uniprotkb:A9JPG0|uniprotkb:B0BK85|uniprotkb:B1GWE7|uniprotkb:B2CR03|uniprotkb:B0LUZ6|uniprotkb:B0UYW1|uniprotkb:B2LVF9|uniprotkb:B2NJ29|uniprotkb:B2ZCY1|uniprotkb:B3VTP8|uniprotkb:B3VTQ3|uniprotkb:B5A8Y2|uniprotkb:B5A8Y3|uniprotkb:C0LAB5|uniprotkb:B5B8U0|uniprotkb:B5B9V5|uniprotkb:B5B9V6|uniprotkb:B5LZ25|uniprotkb:B5QSK8|uniprotkb:B6VCX2|uniprotkb:B6VEL9|uniprotkb:B7UDB2|uniprotkb:B9VRA4|uniprotkb:B9X248|uniprotkb:Q0PGR5|uniprotkb:O02876|uniprotkb:O02930|uniprotkb:O19585|uniprotkb:O19718|uniprotkb:O19788|uniprotkb:O46699|uniprotkb:O46793|uniprotkb:O46872|uniprotkb:O62869|uniprotkb:O62889|uniprotkb:O77969|uniprotkb:O78047|uniprotkb:O78210|uniprotkb:O98212|uniprotkb:P01912|uniprotkb:P01914|uniprotkb:P04229|uniprotkb:P13758|uniprotkb:P13760|uniprotkb:P13761|uniprotkb:P20039|uniprotkb:P79545|uniprotkb:Q06662|uniprotkb:Q0PQ39|uniprotkb:Q14280|uniprotkb:Q14QT2|uniprotkb:Q155F7|uniprotkb:Q19AF2|uniprotkb:Q19K86|uniprotkb:Q1AP33|uniprotkb:Q1G0Z9|uniprotkb:Q1JRP3|uniprotkb:Q1KLJ6|uniprotkb:Q27PR6|uniprotkb:Q27PR7|uniprotkb:Q29673|uniprotkb:Q29720|uniprotkb:Q29722|uniprotkb:Q29734|uniprotkb:Q29770|uniprotkb:Q29771|uniprotkb:Q768U2|uniprotkb:Q29772|uniprotkb:Q29790|uniprotkb:Q29792|uniprotkb:Q29800|uniprotkb:Q29806|uniprotkb:Q29833|uniprotkb:Q29874|uniprotkb:Q29886|uniprotkb:Q29968|uniprotkb:Q29974|uniprotkb:Q29975|uniprotkb:Q2A120|uniprotkb:Q2HZE5|uniprotkb:Q2L9H4|uniprotkb:Q2LE76|uniprotkb:Q2MF40|uniprotkb:Q2MJA6|uniprotkb:Q2MZ92|uniprotkb:Q2VQU1|uniprotkb:Q2YHQ2|uniprotkb:Q30006|uniprotkb:Q30108|uniprotkb:Q30112|uniprotkb:Q30115|uniprotkb:Q30116|uniprotkb:Q30117|uniprotkb:Q30120|uniprotkb:Q30134|uniprotkb:Q30142|uniprotkb:Q30149|uniprotkb:Q30159|uniprotkb:Q30166|uniprotkb:Q30167|uniprotkb:Q30200|uniprotkb:Q307W5|uniprotkb:Q31636|uniprotkb:Q32MY7|uniprotkb:Q3HUP9|uniprotkb:Q3KTM1|uniprotkb:Q3LA84|uniprotkb:Q3LA87|uniprotkb:Q3LA88|uniprotkb:Q3LA89|uniprotkb:Q3LA90|uniprotkb:Q3LA91|uniprotkb:Q3LA92|uniprotkb:Q3LA93|uniprotkb:Q3LA94|uniprotkb:Q3LA95|uniprotkb:Q3LA96|uniprotkb:Q3LA97|uniprotkb:Q3LA98|uniprotkb:Q3LA99|uniprotkb:Q3LAA0|uniprotkb:Q3LAA1|uniprotkb:Q3LAA2|uniprotkb:Q3MQ60|uniprotkb:Q3T919|uniprotkb:Q4PRC3|uniprotkb:Q4PRC5|uniprotkb:Q4VZY7|uniprotkb:Q53IG1|uniprotkb:Q56FN9|uniprotkb:Q56FP1|uniprotkb:Q56FP2|uniprotkb:Q56FP3|uniprotkb:Q58F52|uniprotkb:Q5BM92|uniprotkb:Q5EER6|uniprotkb:Q5K3W2|uniprotkb:Q5NDB9|uniprotkb:Q5U9W6|uniprotkb:Q5UBA2|uniprotkb:Q5UT58|uniprotkb:Q5W3L4|uniprotkb:Q5Y7A7|uniprotkb:Q5Y7B0|uniprotkb:Q5Y7B9|uniprotkb:Q5Y7E9|uniprotkb:Q5Y7G0|uniprotkb:Q683P7|uniprotkb:Q6REE2|uniprotkb:Q6T865|uniprotkb:Q6U387|uniprotkb:Q701T1|uniprotkb:Q70GL2|uniprotkb:Q70Q85|uniprotkb:Q768U4|uniprotkb:Q7M2H4|uniprotkb:Q7YNY9|uniprotkb:Q7YP03|uniprotkb:Q7YP04|uniprotkb:Q7YQ26|uniprotkb:Q7YQA3|uniprotkb:Q7YQA5|uniprotkb:Q860D8|uniprotkb:Q860D9|uniprotkb:Q860E5|uniprotkb:Q860H8|uniprotkb:Q860S0|uniprotkb:Q860Z3|uniprotkb:Q861G6|uniprotkb:Q861H0|uniprotkb:Q861H4|uniprotkb:Q861H5|uniprotkb:Q861H7|uniprotkb:Q861H8|uniprotkb:Q8HWQ6|uniprotkb:Q8MH59|uniprotkb:Q8MH60|uniprotkb:Q8WLU3|uniprotkb:Q8WMA0|uniprotkb:Q95348|uniprotkb:Q95383|uniprotkb:Q95389|uniprotkb:Q95461|uniprotkb:Q95HK1|uniprotkb:Q95HL0|uniprotkb:Q95HL1|uniprotkb:Q95IE3|uniprotkb:Q95IG2|uniprotkb:Q95IT6|uniprotkb:Q96HZ9|uniprotkb:Q9BCL7|uniprotkb:Q9BCP0|uniprotkb:Q9BCP1|uniprotkb:Q9BCP2|uniprotkb:Q9BCP5|uniprotkb:Q9BD21|uniprotkb:Q9BD33|uniprotkb:Q9BD40|uniprotkb:Q9GIK5|uniprotkb:Q9GIL5|uniprotkb:Q9GIL6|uniprotkb:Q9GIP3|uniprotkb:Q9GIX8|uniprotkb:Q9GIY0|uniprotkb:Q9GIY1|uniprotkb:Q9GIY2|intact:EBI-3866098|intact:EBI-13953066|uniprotkb:Q9GIY3|uniprotkb:Q9GJ25|uniprotkb:Q9GJ56|uniprotkb:Q9GJ57|uniprotkb:Q9GJ58|uniprotkb:Q9GJ60|uniprotkb:Q9GJF8|uniprotkb:Q9GJF9|uniprotkb:Q9GJG0|uniprotkb:Q9MXZ0|uniprotkb:Q9MXZ5|uniprotkb:Q9MY45|uniprotkb:Q9MY56|uniprotkb:Q9MYF5|uniprotkb:Q9TPB6|uniprotkb:Q9TPW1|uniprotkb:Q9TPW3|uniprotkb:Q9TPW9|uniprotkb:Q9TPX4|uniprotkb:Q9TQ37|uniprotkb:Q9TQ91|uniprotkb:Q9TQE0|uniprotkb:Q9UBY1|uniprotkb:Q9UIM9|uniprotkb:Q9UIN0|uniprotkb:Q9XRX1|uniprotkb:Q9XRY4|uniprotkb:Q9Y453|uniprotkb:Q9Y4H7|intact:EBI-13953170|intact:EBI-2877159	intact:EBI-2796192	psi-mi:drb1_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)|uniprotkb:Human leukocyte antigen DRB1(gene name synonym)	psi-mi:katg_fratt(display_long)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:FTT_0721c(locus name)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806366|imex:IM-13779-1022	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000196126.12(gene)|ensembl:ENST00000360004.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002842""(positive regulation of T cell mediated immune response to tumor cell)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0008544""(epidermis development)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032653""(regulation of interleukin-10 production)|go:""GO:0032673""(regulation of interleukin-4 production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0042088""(T-helper 1 type immune response)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051262""(protein tetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01911|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FYT|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6HBY|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_001230894.1|refseq:NP_002115.2|refseq:XP_011546040.1|efo:""Orphanet:2073""|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:220407""|efo:""Orphanet:397""|efo:""Orphanet:477738""|efo:""Orphanet:536""|efo:""Orphanet:545""|efo:""Orphanet:703""|efo:""Orphanet:747""|efo:""Orphanet:797""|efo:""Orphanet:83465""|efo:""Orphanet:85414""|panther:PTHR19944(orthology-group)"	"refseq:YP_169735.1|interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|refseq:WP_003020536.1|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YdQX0KNIxO5tYjgm6hdRRZfNlk49606	rogid:UVLspYdPWJwb7VPBG0xNq1Pp2KQ177416	intact-crc:5C5039D84B3DEA35|rigid:YOdedSv1ZZw17nTEXujkEEK0KMw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF60	uniprotkb:P01911	intact:EBI-2799293	intact:EBI-1033104|uniprotkb:O19717|uniprotkb:O19739|uniprotkb:P13759|uniprotkb:Q29875|uniprotkb:Q30145|uniprotkb:Q9GIX9|uniprotkb:Q9GIY4|uniprotkb:Q9MY13|uniprotkb:Q9XRY5|ensembl:ENSP00000353099.5|uniprotkb:A0MWF2|uniprotkb:A0N0W1|uniprotkb:A2ICT1|uniprotkb:A2TGX3|uniprotkb:A4F5N0|uniprotkb:A4ZXA5|uniprotkb:A4ZXA6|uniprotkb:A4ZY86|uniprotkb:A5H000|uniprotkb:A5HKN8|uniprotkb:A7DZP9|uniprotkb:A7LA26|uniprotkb:A7UHG2|uniprotkb:A7X5B1|uniprotkb:A7X5B7|uniprotkb:A7X5E0|uniprotkb:A7X5E6|uniprotkb:A7X5H8|uniprotkb:A7X5J4|uniprotkb:A7X5K7|uniprotkb:A8K098|uniprotkb:A8YQE9|uniprotkb:A9JPG0|uniprotkb:B0BK85|uniprotkb:B1GWE7|uniprotkb:B2CR03|uniprotkb:B0LUZ6|uniprotkb:B0UYW1|uniprotkb:B2LVF9|uniprotkb:B2NJ29|uniprotkb:B2ZCY1|uniprotkb:B3VTP8|uniprotkb:B3VTQ3|uniprotkb:B5A8Y2|uniprotkb:B5A8Y3|uniprotkb:C0LAB5|uniprotkb:B5B8U0|uniprotkb:B5B9V5|uniprotkb:B5B9V6|uniprotkb:B5LZ25|uniprotkb:B5QSK8|uniprotkb:B6VCX2|uniprotkb:B6VEL9|uniprotkb:B7UDB2|uniprotkb:B9VRA4|uniprotkb:B9X248|uniprotkb:Q0PGR5|uniprotkb:O02876|uniprotkb:O02930|uniprotkb:O19585|uniprotkb:O19718|uniprotkb:O19788|uniprotkb:O46699|uniprotkb:O46793|uniprotkb:O46872|uniprotkb:O62869|uniprotkb:O62889|uniprotkb:O77969|uniprotkb:O78047|uniprotkb:O78210|uniprotkb:O98212|uniprotkb:P01912|uniprotkb:P01914|uniprotkb:P04229|uniprotkb:P13758|uniprotkb:P13760|uniprotkb:P13761|uniprotkb:P20039|uniprotkb:P79545|uniprotkb:Q06662|uniprotkb:Q0PQ39|uniprotkb:Q14280|uniprotkb:Q14QT2|uniprotkb:Q155F7|uniprotkb:Q19AF2|uniprotkb:Q19K86|uniprotkb:Q1AP33|uniprotkb:Q1G0Z9|uniprotkb:Q1JRP3|uniprotkb:Q1KLJ6|uniprotkb:Q27PR6|uniprotkb:Q27PR7|uniprotkb:Q29673|uniprotkb:Q29720|uniprotkb:Q29722|uniprotkb:Q29734|uniprotkb:Q29770|uniprotkb:Q29771|uniprotkb:Q768U2|uniprotkb:Q29772|uniprotkb:Q29790|uniprotkb:Q29792|uniprotkb:Q29800|uniprotkb:Q29806|uniprotkb:Q29833|uniprotkb:Q29874|uniprotkb:Q29886|uniprotkb:Q29968|uniprotkb:Q29974|uniprotkb:Q29975|uniprotkb:Q2A120|uniprotkb:Q2HZE5|uniprotkb:Q2L9H4|uniprotkb:Q2LE76|uniprotkb:Q2MF40|uniprotkb:Q2MJA6|uniprotkb:Q2MZ92|uniprotkb:Q2VQU1|uniprotkb:Q2YHQ2|uniprotkb:Q30006|uniprotkb:Q30108|uniprotkb:Q30112|uniprotkb:Q30115|uniprotkb:Q30116|uniprotkb:Q30117|uniprotkb:Q30120|uniprotkb:Q30134|uniprotkb:Q30142|uniprotkb:Q30149|uniprotkb:Q30159|uniprotkb:Q30166|uniprotkb:Q30167|uniprotkb:Q30200|uniprotkb:Q307W5|uniprotkb:Q31636|uniprotkb:Q32MY7|uniprotkb:Q3HUP9|uniprotkb:Q3KTM1|uniprotkb:Q3LA84|uniprotkb:Q3LA87|uniprotkb:Q3LA88|uniprotkb:Q3LA89|uniprotkb:Q3LA90|uniprotkb:Q3LA91|uniprotkb:Q3LA92|uniprotkb:Q3LA93|uniprotkb:Q3LA94|uniprotkb:Q3LA95|uniprotkb:Q3LA96|uniprotkb:Q3LA97|uniprotkb:Q3LA98|uniprotkb:Q3LA99|uniprotkb:Q3LAA0|uniprotkb:Q3LAA1|uniprotkb:Q3LAA2|uniprotkb:Q3MQ60|uniprotkb:Q3T919|uniprotkb:Q4PRC3|uniprotkb:Q4PRC5|uniprotkb:Q4VZY7|uniprotkb:Q53IG1|uniprotkb:Q56FN9|uniprotkb:Q56FP1|uniprotkb:Q56FP2|uniprotkb:Q56FP3|uniprotkb:Q58F52|uniprotkb:Q5BM92|uniprotkb:Q5EER6|uniprotkb:Q5K3W2|uniprotkb:Q5NDB9|uniprotkb:Q5U9W6|uniprotkb:Q5UBA2|uniprotkb:Q5UT58|uniprotkb:Q5W3L4|uniprotkb:Q5Y7A7|uniprotkb:Q5Y7B0|uniprotkb:Q5Y7B9|uniprotkb:Q5Y7E9|uniprotkb:Q5Y7G0|uniprotkb:Q683P7|uniprotkb:Q6REE2|uniprotkb:Q6T865|uniprotkb:Q6U387|uniprotkb:Q701T1|uniprotkb:Q70GL2|uniprotkb:Q70Q85|uniprotkb:Q768U4|uniprotkb:Q7M2H4|uniprotkb:Q7YNY9|uniprotkb:Q7YP03|uniprotkb:Q7YP04|uniprotkb:Q7YQ26|uniprotkb:Q7YQA3|uniprotkb:Q7YQA5|uniprotkb:Q860D8|uniprotkb:Q860D9|uniprotkb:Q860E5|uniprotkb:Q860H8|uniprotkb:Q860S0|uniprotkb:Q860Z3|uniprotkb:Q861G6|uniprotkb:Q861H0|uniprotkb:Q861H4|uniprotkb:Q861H5|uniprotkb:Q861H7|uniprotkb:Q861H8|uniprotkb:Q8HWQ6|uniprotkb:Q8MH59|uniprotkb:Q8MH60|uniprotkb:Q8WLU3|uniprotkb:Q8WMA0|uniprotkb:Q95348|uniprotkb:Q95383|uniprotkb:Q95389|uniprotkb:Q95461|uniprotkb:Q95HK1|uniprotkb:Q95HL0|uniprotkb:Q95HL1|uniprotkb:Q95IE3|uniprotkb:Q95IG2|uniprotkb:Q95IT6|uniprotkb:Q96HZ9|uniprotkb:Q9BCL7|uniprotkb:Q9BCP0|uniprotkb:Q9BCP1|uniprotkb:Q9BCP2|uniprotkb:Q9BCP5|uniprotkb:Q9BD21|uniprotkb:Q9BD33|uniprotkb:Q9BD40|uniprotkb:Q9GIK5|uniprotkb:Q9GIL5|uniprotkb:Q9GIL6|uniprotkb:Q9GIP3|uniprotkb:Q9GIX8|uniprotkb:Q9GIY0|uniprotkb:Q9GIY1|uniprotkb:Q9GIY2|intact:EBI-3866098|intact:EBI-13953066|uniprotkb:Q9GIY3|uniprotkb:Q9GJ25|uniprotkb:Q9GJ56|uniprotkb:Q9GJ57|uniprotkb:Q9GJ58|uniprotkb:Q9GJ60|uniprotkb:Q9GJF8|uniprotkb:Q9GJF9|uniprotkb:Q9GJG0|uniprotkb:Q9MXZ0|uniprotkb:Q9MXZ5|uniprotkb:Q9MY45|uniprotkb:Q9MY56|uniprotkb:Q9MYF5|uniprotkb:Q9TPB6|uniprotkb:Q9TPW1|uniprotkb:Q9TPW3|uniprotkb:Q9TPW9|uniprotkb:Q9TPX4|uniprotkb:Q9TQ37|uniprotkb:Q9TQ91|uniprotkb:Q9TQE0|uniprotkb:Q9UBY1|uniprotkb:Q9UIM9|uniprotkb:Q9UIN0|uniprotkb:Q9XRX1|uniprotkb:Q9XRY4|uniprotkb:Q9Y453|uniprotkb:Q9Y4H7|intact:EBI-13953170|intact:EBI-2877159	"psi-mi:dnlj_fratt(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:""Polydeoxyribonucleotide synthase [NAD(+)]""(gene name synonym)|uniprotkb:FTT_1387c(locus name)"	psi-mi:drb1_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)|uniprotkb:Human leukocyte antigen DRB1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806380|imex:IM-13779-1023	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_170332.1|interpro:IPR001357(BRCT)|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR004149(Zinc-finger, NAD-dependent DNA ligase C4-type)|go:""GO:0003677""(DNA binding)|go:""GO:0003911""(""DNA ligase (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006288""(obsolete base-excision repair, DNA ligation)|go:""GO:0046872""(metal ion binding)|refseq:WP_003024021.1|interpro:IPR033136|interpro:IPR036420|interpro:IPR041663"	"ensembl:ENSG00000196126.12(gene)|ensembl:ENST00000360004.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002842""(positive regulation of T cell mediated immune response to tumor cell)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0008544""(epidermis development)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032653""(regulation of interleukin-10 production)|go:""GO:0032673""(regulation of interleukin-4 production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0042088""(T-helper 1 type immune response)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051262""(protein tetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01911|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FYT|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6HBY|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_001230894.1|refseq:NP_002115.2|refseq:XP_011546040.1|efo:""Orphanet:2073""|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:220407""|efo:""Orphanet:397""|efo:""Orphanet:477738""|efo:""Orphanet:536""|efo:""Orphanet:545""|efo:""Orphanet:703""|efo:""Orphanet:747""|efo:""Orphanet:797""|efo:""Orphanet:83465""|efo:""Orphanet:85414""|panther:PTHR19944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rHqrcgB9uMgr4visMI6R3FjEECc177416	rogid:YdQX0KNIxO5tYjgm6hdRRZfNlk49606	intact-crc:C7CD48D84ABC29D9|rigid:Ji3RVCV3w7Kv/ieaVqCNq3LdOUg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF67	uniprotkb:P01911	intact:EBI-2799446|uniprotkb:A0A0G2RPA4	intact:EBI-1033104|uniprotkb:O19717|uniprotkb:O19739|uniprotkb:P13759|uniprotkb:Q29875|uniprotkb:Q30145|uniprotkb:Q9GIX9|uniprotkb:Q9GIY4|uniprotkb:Q9MY13|uniprotkb:Q9XRY5|ensembl:ENSP00000353099.5|uniprotkb:A0MWF2|uniprotkb:A0N0W1|uniprotkb:A2ICT1|uniprotkb:A2TGX3|uniprotkb:A4F5N0|uniprotkb:A4ZXA5|uniprotkb:A4ZXA6|uniprotkb:A4ZY86|uniprotkb:A5H000|uniprotkb:A5HKN8|uniprotkb:A7DZP9|uniprotkb:A7LA26|uniprotkb:A7UHG2|uniprotkb:A7X5B1|uniprotkb:A7X5B7|uniprotkb:A7X5E0|uniprotkb:A7X5E6|uniprotkb:A7X5H8|uniprotkb:A7X5J4|uniprotkb:A7X5K7|uniprotkb:A8K098|uniprotkb:A8YQE9|uniprotkb:A9JPG0|uniprotkb:B0BK85|uniprotkb:B1GWE7|uniprotkb:B2CR03|uniprotkb:B0LUZ6|uniprotkb:B0UYW1|uniprotkb:B2LVF9|uniprotkb:B2NJ29|uniprotkb:B2ZCY1|uniprotkb:B3VTP8|uniprotkb:B3VTQ3|uniprotkb:B5A8Y2|uniprotkb:B5A8Y3|uniprotkb:C0LAB5|uniprotkb:B5B8U0|uniprotkb:B5B9V5|uniprotkb:B5B9V6|uniprotkb:B5LZ25|uniprotkb:B5QSK8|uniprotkb:B6VCX2|uniprotkb:B6VEL9|uniprotkb:B7UDB2|uniprotkb:B9VRA4|uniprotkb:B9X248|uniprotkb:Q0PGR5|uniprotkb:O02876|uniprotkb:O02930|uniprotkb:O19585|uniprotkb:O19718|uniprotkb:O19788|uniprotkb:O46699|uniprotkb:O46793|uniprotkb:O46872|uniprotkb:O62869|uniprotkb:O62889|uniprotkb:O77969|uniprotkb:O78047|uniprotkb:O78210|uniprotkb:O98212|uniprotkb:P01912|uniprotkb:P01914|uniprotkb:P04229|uniprotkb:P13758|uniprotkb:P13760|uniprotkb:P13761|uniprotkb:P20039|uniprotkb:P79545|uniprotkb:Q06662|uniprotkb:Q0PQ39|uniprotkb:Q14280|uniprotkb:Q14QT2|uniprotkb:Q155F7|uniprotkb:Q19AF2|uniprotkb:Q19K86|uniprotkb:Q1AP33|uniprotkb:Q1G0Z9|uniprotkb:Q1JRP3|uniprotkb:Q1KLJ6|uniprotkb:Q27PR6|uniprotkb:Q27PR7|uniprotkb:Q29673|uniprotkb:Q29720|uniprotkb:Q29722|uniprotkb:Q29734|uniprotkb:Q29770|uniprotkb:Q29771|uniprotkb:Q768U2|uniprotkb:Q29772|uniprotkb:Q29790|uniprotkb:Q29792|uniprotkb:Q29800|uniprotkb:Q29806|uniprotkb:Q29833|uniprotkb:Q29874|uniprotkb:Q29886|uniprotkb:Q29968|uniprotkb:Q29974|uniprotkb:Q29975|uniprotkb:Q2A120|uniprotkb:Q2HZE5|uniprotkb:Q2L9H4|uniprotkb:Q2LE76|uniprotkb:Q2MF40|uniprotkb:Q2MJA6|uniprotkb:Q2MZ92|uniprotkb:Q2VQU1|uniprotkb:Q2YHQ2|uniprotkb:Q30006|uniprotkb:Q30108|uniprotkb:Q30112|uniprotkb:Q30115|uniprotkb:Q30116|uniprotkb:Q30117|uniprotkb:Q30120|uniprotkb:Q30134|uniprotkb:Q30142|uniprotkb:Q30149|uniprotkb:Q30159|uniprotkb:Q30166|uniprotkb:Q30167|uniprotkb:Q30200|uniprotkb:Q307W5|uniprotkb:Q31636|uniprotkb:Q32MY7|uniprotkb:Q3HUP9|uniprotkb:Q3KTM1|uniprotkb:Q3LA84|uniprotkb:Q3LA87|uniprotkb:Q3LA88|uniprotkb:Q3LA89|uniprotkb:Q3LA90|uniprotkb:Q3LA91|uniprotkb:Q3LA92|uniprotkb:Q3LA93|uniprotkb:Q3LA94|uniprotkb:Q3LA95|uniprotkb:Q3LA96|uniprotkb:Q3LA97|uniprotkb:Q3LA98|uniprotkb:Q3LA99|uniprotkb:Q3LAA0|uniprotkb:Q3LAA1|uniprotkb:Q3LAA2|uniprotkb:Q3MQ60|uniprotkb:Q3T919|uniprotkb:Q4PRC3|uniprotkb:Q4PRC5|uniprotkb:Q4VZY7|uniprotkb:Q53IG1|uniprotkb:Q56FN9|uniprotkb:Q56FP1|uniprotkb:Q56FP2|uniprotkb:Q56FP3|uniprotkb:Q58F52|uniprotkb:Q5BM92|uniprotkb:Q5EER6|uniprotkb:Q5K3W2|uniprotkb:Q5NDB9|uniprotkb:Q5U9W6|uniprotkb:Q5UBA2|uniprotkb:Q5UT58|uniprotkb:Q5W3L4|uniprotkb:Q5Y7A7|uniprotkb:Q5Y7B0|uniprotkb:Q5Y7B9|uniprotkb:Q5Y7E9|uniprotkb:Q5Y7G0|uniprotkb:Q683P7|uniprotkb:Q6REE2|uniprotkb:Q6T865|uniprotkb:Q6U387|uniprotkb:Q701T1|uniprotkb:Q70GL2|uniprotkb:Q70Q85|uniprotkb:Q768U4|uniprotkb:Q7M2H4|uniprotkb:Q7YNY9|uniprotkb:Q7YP03|uniprotkb:Q7YP04|uniprotkb:Q7YQ26|uniprotkb:Q7YQA3|uniprotkb:Q7YQA5|uniprotkb:Q860D8|uniprotkb:Q860D9|uniprotkb:Q860E5|uniprotkb:Q860H8|uniprotkb:Q860S0|uniprotkb:Q860Z3|uniprotkb:Q861G6|uniprotkb:Q861H0|uniprotkb:Q861H4|uniprotkb:Q861H5|uniprotkb:Q861H7|uniprotkb:Q861H8|uniprotkb:Q8HWQ6|uniprotkb:Q8MH59|uniprotkb:Q8MH60|uniprotkb:Q8WLU3|uniprotkb:Q8WMA0|uniprotkb:Q95348|uniprotkb:Q95383|uniprotkb:Q95389|uniprotkb:Q95461|uniprotkb:Q95HK1|uniprotkb:Q95HL0|uniprotkb:Q95HL1|uniprotkb:Q95IE3|uniprotkb:Q95IG2|uniprotkb:Q95IT6|uniprotkb:Q96HZ9|uniprotkb:Q9BCL7|uniprotkb:Q9BCP0|uniprotkb:Q9BCP1|uniprotkb:Q9BCP2|uniprotkb:Q9BCP5|uniprotkb:Q9BD21|uniprotkb:Q9BD33|uniprotkb:Q9BD40|uniprotkb:Q9GIK5|uniprotkb:Q9GIL5|uniprotkb:Q9GIL6|uniprotkb:Q9GIP3|uniprotkb:Q9GIX8|uniprotkb:Q9GIY0|uniprotkb:Q9GIY1|uniprotkb:Q9GIY2|intact:EBI-3866098|intact:EBI-13953066|uniprotkb:Q9GIY3|uniprotkb:Q9GJ25|uniprotkb:Q9GJ56|uniprotkb:Q9GJ57|uniprotkb:Q9GJ58|uniprotkb:Q9GJ60|uniprotkb:Q9GJF8|uniprotkb:Q9GJF9|uniprotkb:Q9GJG0|uniprotkb:Q9MXZ0|uniprotkb:Q9MXZ5|uniprotkb:Q9MY45|uniprotkb:Q9MY56|uniprotkb:Q9MYF5|uniprotkb:Q9TPB6|uniprotkb:Q9TPW1|uniprotkb:Q9TPW3|uniprotkb:Q9TPW9|uniprotkb:Q9TPX4|uniprotkb:Q9TQ37|uniprotkb:Q9TQ91|uniprotkb:Q9TQE0|uniprotkb:Q9UBY1|uniprotkb:Q9UIM9|uniprotkb:Q9UIN0|uniprotkb:Q9XRX1|uniprotkb:Q9XRY4|uniprotkb:Q9Y453|uniprotkb:Q9Y4H7|intact:EBI-13953170|intact:EBI-2877159	psi-mi:q5nf67_fratt(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:FTT_1376(locus name)	psi-mi:drb1_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)|uniprotkb:Human leukocyte antigen DRB1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806373|imex:IM-13779-1025	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003231(""Acyl carrier protein (ACP)"")|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR006162(Phosphopantetheine attachment site)|refseq:YP_170325.1|go:""GO:0000035""(acyl binding)|go:""GO:0000036""(acyl carrier activity)|go:""GO:0005829""(cytosol)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0036104""(Kdo2-lipid A biosynthetic process)|interpro:IPR036736|refseq:WP_003025404.1"	"ensembl:ENSG00000196126.12(gene)|ensembl:ENST00000360004.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002842""(positive regulation of T cell mediated immune response to tumor cell)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0008544""(epidermis development)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032653""(regulation of interleukin-10 production)|go:""GO:0032673""(regulation of interleukin-4 production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0042088""(T-helper 1 type immune response)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051262""(protein tetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01911|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FYT|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6HBY|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_001230894.1|refseq:NP_002115.2|refseq:XP_011546040.1|efo:""Orphanet:2073""|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:220407""|efo:""Orphanet:397""|efo:""Orphanet:477738""|efo:""Orphanet:536""|efo:""Orphanet:545""|efo:""Orphanet:703""|efo:""Orphanet:747""|efo:""Orphanet:797""|efo:""Orphanet:83465""|efo:""Orphanet:85414""|panther:PTHR19944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zB081U74KR2zeTgcfB7HSoE5ozo177416	rogid:YdQX0KNIxO5tYjgm6hdRRZfNlk49606	intact-crc:B0CD48D84B2AD5B7|rigid:0uhpBMWZkbdbtJ652W+TqvG4syg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NE99	uniprotkb:O00165	intact:EBI-2796415	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	psi-mi:secb2_fratt(display_long)|uniprotkb:FTT_1749(locus name)|uniprotkb:secB2(gene name)|psi-mi:secB2(display_short)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806387|imex:IM-13779-1026	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0006457""(protein folding)|go:""GO:0015031""(protein transport)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051262""(protein tetramerization)|interpro:IPR003708(Bacterial protein export chaperone SecB)|refseq:YP_170643.1|refseq:WP_003013731.1|interpro:IPR035958"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:/Ln+Ppl3hIcqmxWI4W9Mf0EKLFw177416	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	intact-crc:ED831954CB8E1147|rigid:Eb253xwG2UtqsnAo285bwSuhwnE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV3	uniprotkb:P01909	intact:EBI-2797317	intact:EBI-713389|uniprotkb:O19630|uniprotkb:Q30101|uniprotkb:Q9UM31|intact:EBI-1038000|uniprotkb:Q06751|uniprotkb:Q29994|uniprotkb:Q30086|uniprotkb:Q5Y7D5|uniprotkb:O19706|uniprotkb:P01907|uniprotkb:P04225|uniprotkb:P04226|uniprotkb:P79553|uniprotkb:Q29876|uniprotkb:Q2Q6Y6|uniprotkb:Q2Q6Y7|uniprotkb:Q2Q6Y8|uniprotkb:Q2WCM3|uniprotkb:Q30064|uniprotkb:Q30067|uniprotkb:Q30068|uniprotkb:Q30070|uniprotkb:Q30071|uniprotkb:Q30072|uniprotkb:Q30073|uniprotkb:Q6ICU6|uniprotkb:Q6PR46|uniprotkb:Q6QDB1|uniprotkb:Q860W2|uniprotkb:Q860W4|uniprotkb:Q9BD37|uniprotkb:Q9TPM3|uniprotkb:Q5Y7F5|uniprotkb:P01908|uniprotkb:P05536|ensembl:ENSP00000339398.5|ensembl:ENSP00000364087.2|ensembl:ENSP00000372738.2|ensembl:ENSP00000378767.1|ensembl:ENSP00000382583.1|ensembl:ENSP00000382586.1|ensembl:ENSP00000387892.1|ensembl:ENSP00000413237.2	psi-mi:q5ngv3_fratt(display_long)|uniprotkb:FTT_0726c(locus name)	psi-mi:dqa1_human(display_long)|uniprotkb:DC-alpha(gene name synonym)|uniprotkb:HLA-DCA(gene name synonym)|uniprotkb:DC-1 alpha chain(gene name synonym)|uniprotkb:MHC class II DQA1(gene name synonym)|uniprotkb:HLA-DQA1(gene name)|psi-mi:HLA-DQA1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806401|imex:IM-13779-1030	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0006629""(lipid metabolic process)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|interpro:IPR017946|refseq:YP_169739.1|interpro:IPR030395|refseq:WP_003020543.1"	"ensembl:ENSG00000196735.13(gene)|ensembl:ENSG00000206305.12(gene)|ensembl:ENSG00000232062.9(gene)|ensembl:ENST00000343139.11(transcript)|ensembl:ENST00000374949.2(transcript)|ensembl:ENST00000383251.6(transcript)|ensembl:ENST00000395363.5(transcript)|ensembl:ENST00000399675.5(transcript)|ensembl:ENST00000399678.5(transcript)|ensembl:ENST00000418023.5(transcript)|ensembl:ENST00000444296.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002250""(adaptive immune response)|rcsb pdb:5KSU|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01909|rcsb pdb:1JK8|rcsb pdb:1S9V|rcsb pdb:1UVQ|rcsb pdb:2NNA|rcsb pdb:4GG6|rcsb pdb:4OZF|rcsb pdb:4OZG|rcsb pdb:4OZH|rcsb pdb:4OZI|rcsb pdb:5KSA|rcsb pdb:5KSB|rcsb pdb:5KSV|rcsb pdb:6MFF|rcsb pdb:6MFG|rcsb pdb:6U3M|rcsb pdb:6U3N|rcsb pdb:6XP6|rcsb pdb:7SG0|rcsb pdb:7SG1|rcsb pdb:7SG2|rcsb pdb:8VSP|rcsb pdb:8W83|rcsb pdb:8W84|rcsb pdb:8W85|rcsb pdb:8W86|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_002113.2|efo:""Orphanet:391490""|efo:""Orphanet:930""|panther:PTHR19944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3e+5yrpF/Mx2IYeXH2egqOFVYbs177416	rogid:cU5mVu+BL26LvdsGgq5F64+4Wm09606	intact-crc:89FC7FC69128ED18|rigid:PUxKRTyfth/Asuq9IsY8MyKUaiE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11169	uniprotkb:Q5NID2	intact:EBI-725116|uniprotkb:Q6I9U2|uniprotkb:Q9UG15|uniprotkb:D3DUU6|uniprotkb:B2R606|ensembl:ENSP00000075120.7|ensembl:ENSP00000516774.1	intact:EBI-2796292	psi-mi:gtr3_human(display_long)|uniprotkb:Glucose transporter type 3, brain(gene name synonym)|uniprotkb:SLC2A3(gene name)|psi-mi:SLC2A3(display_short)|uniprotkb:GLUT3(gene name synonym)	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806429|imex:IM-13779-1027	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:399""|ensembl:ENSG00000059804.18(gene)|ensembl:ENST00000075120.12(transcript)|ensembl:ENST00000707174.1(transcript)|go:""GO:0005354""(galactose transmembrane transporter activity)|go:""GO:0005536""(D-glucose binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0015757""(galactose transmembrane transport)|go:""GO:0016020""(membrane)|go:""GO:0016235""(aggresome)|go:""GO:0019852""(L-ascorbic acid metabolic process)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0033300""(dehydroascorbic acid transmembrane transporter activity)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042995""(cell projection)|go:""GO:0043204""(perikaryon)|go:""GO:0046323""(D-glucose import)|go:""GO:0055056""(D-glucose transmembrane transporter activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0070837""(dehydroascorbic acid transport)|go:""GO:0098708""(D-glucose import across plasma membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1904659""(D-glucose transmembrane transport)|interpro:IPR002945(Glucose transporter GLUT3, type 3)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|interpro:IPR045263|mint:P11169|rcsb pdb:4ZW9|rcsb pdb:4ZWB|rcsb pdb:4ZWC|rcsb pdb:5C65|rcsb pdb:7CRZ|rcsb pdb:7SPS|rcsb pdb:7SPT|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-6798695|reactome:R-HSA-9022699|refseq:NP_008862.1|panther:PTHR23503(orthology-group)"	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4lvD/2COzfHcIKxN1l9FsXOJWnk9606	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	intact-crc:EA9B8A72F372599A|rigid:qLFqWKKHG9FL9NndaKFd1k70B8M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P84243	uniprotkb:Q5NI66	intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810.3|ensembl:ENSP00000355778.1|ensembl:ENSP00000355780.3|ensembl:ENSP00000355781.1|ensembl:ENSP00000465813.1|ensembl:ENSP00000466020.1|ensembl:ENSP00000468714.1|ensembl:ENSP00000499275.1|ensembl:ENSP00000499385.1|ensembl:ENSP00000499800.1	intact:EBI-2797252|uniprotkb:A0A0G2RM61	psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name)	psi-mi:q5ni66_fratt(display_long)|uniprotkb:acpA(gene name)|psi-mi:acpA(display_short)|uniprotkb:FTT_0221(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806408|imex:IM-13779-1028	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002098.1|refseq:NP_005315.1|dip:DIP-40046N|ensembl:ENSG00000132475.10(gene)|ensembl:ENSG00000163041.13(gene)|ensembl:ENST00000254810.8(transcript)|ensembl:ENST00000366813.1(transcript)|ensembl:ENST00000366815.10(transcript)|ensembl:ENST00000366816.5(transcript)|ensembl:ENST00000586607.5(transcript)|ensembl:ENST00000587560.5(transcript)|ensembl:ENST00000589599.5(transcript)|ensembl:ENST00000655399.1(transcript)|ensembl:ENST00000661429.1(transcript)|ensembl:ENST00000666609.1(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000786""(nucleosome)|go:""GO:0000939""(inner kinetochore)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0001556""(oocyte maturation)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001740""(Barr body)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006997""(nucleus organization)|go:""GO:0007286""(spermatid development)|go:""GO:0007338""(single fertilization)|go:""GO:0007566""(embryo implantation)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008584""(male gonad development)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030527""(structural constituent of chromatin)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0031508""(pericentric heterochromatin formation)|go:""GO:0031509""(subtelomeric heterochromatin formation)|go:""GO:0032200""(telomere organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090230""(regulation of centromere complex assembly)|go:""GO:1902340""(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|rcsb pdb:3QL9|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:3WTP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4GNG|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4U7T|rcsb pdb:4W5A|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7CWH|rcsb pdb:7OKP|rcsb pdb:7V1L|rcsb pdb:7V1M|rcsb pdb:7VCQ|rcsb pdb:7W5M|rcsb pdb:7WBV|rcsb pdb:7WBW|rcsb pdb:7WBX|rcsb pdb:7XSE|rcsb pdb:7XSX|rcsb pdb:7XSZ|rcsb pdb:7XT7|rcsb pdb:7XTD|rcsb pdb:7XTI|rcsb pdb:8JH2|rcsb pdb:8JH3|rcsb pdb:8JH4|rcsb pdb:8KB5|rcsb pdb:9B3P|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-68616|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-9821002|reactome:R-HSA-9821993|reactome:R-HSA-983231|reactome:R-HSA-9841922|reactome:R-HSA-9843940|reactome:R-HSA-9843970|reactome:R-HSA-9845323|panther:PTHR11426(orthology-group)|ensembl:ENSP00000254810.3|ensembl:ENSP00000355778.1|ensembl:ENSP00000355780.3|ensembl:ENSP00000355781.1|ensembl:ENSP00000466020.1|ensembl:ENSP00000468714.1|ensembl:ENSP00000465813.1|ensembl:ENSP00000499800.1|ensembl:ENSP00000499385.1|ensembl:ENSP00000499275.1"	"go:""GO:0034480""(phosphatidylcholine phospholipase C activity)|interpro:IPR007312(Phosphoesterase)|refseq:YP_169276.1|refseq:WP_003021808.1|interpro:IPR017850(Alkaline-phosphatase-like, core domain)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606	rogid:4qC583ToLOkAvm3AlbzGYd39Rt8177416	intact-crc:520C0442BB9DF2E7|rigid:hcf5G93csWCZfncfa0ffR6ByxMw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6FI13	uniprotkb:Q5NGC7	intact:EBI-353620|uniprotkb:P20670|ensembl:ENSP00000358155.2|ensembl:ENSP00000475814.1|uniprotkb:B2R5F0	intact:EBI-2796378|uniprotkb:A0A0G2RMD1	psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym)	psi-mi:q5ngc7_fratt(display_long)|uniprotkb:FTT_0918(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806422|imex:IM-13779-1029	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000288825.1(gene)|ensembl:ENSG00000288859.1(gene)|ensembl:ENST00000369159.3(transcript)|ensembl:ENST00000607355.3(transcript)|go:""GO:0000786""(nucleosome)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0030527""(structural constituent of chromatin)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q6FI13|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|rcsb pdb:9FGQ|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-68616|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-9821002|reactome:R-HSA-9841922|reactome:R-HSA-9843940|reactome:R-HSA-9843970|reactome:R-HSA-9845323|dip:DIP-33167N|panther:PTHR23430(orthology-group)"	refseq:YP_169915.1|interpro:IPR021956|refseq:WP_003020942.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606	rogid:PY6VBLnYAPBQCnx7Cz0BtZWqzy0177416	intact-crc:990D3666DA775ED0|rigid:M6sy/UH6R+r/j6HzhHwUsI/gJe8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P84243	uniprotkb:Q5NGW2	intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810.3|ensembl:ENSP00000355778.1|ensembl:ENSP00000355780.3|ensembl:ENSP00000355781.1|ensembl:ENSP00000465813.1|ensembl:ENSP00000466020.1|ensembl:ENSP00000468714.1|ensembl:ENSP00000499275.1|ensembl:ENSP00000499385.1|ensembl:ENSP00000499800.1	intact:EBI-2796474|uniprotkb:A0A0G2RND5	psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name)	psi-mi:q5ngw2_fratt(display_long)|uniprotkb:FTT_0715(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806415|imex:IM-13779-1031	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002098.1|refseq:NP_005315.1|dip:DIP-40046N|ensembl:ENSG00000132475.10(gene)|ensembl:ENSG00000163041.13(gene)|ensembl:ENST00000254810.8(transcript)|ensembl:ENST00000366813.1(transcript)|ensembl:ENST00000366815.10(transcript)|ensembl:ENST00000366816.5(transcript)|ensembl:ENST00000586607.5(transcript)|ensembl:ENST00000587560.5(transcript)|ensembl:ENST00000589599.5(transcript)|ensembl:ENST00000655399.1(transcript)|ensembl:ENST00000661429.1(transcript)|ensembl:ENST00000666609.1(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000786""(nucleosome)|go:""GO:0000939""(inner kinetochore)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0001556""(oocyte maturation)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001740""(Barr body)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006997""(nucleus organization)|go:""GO:0007286""(spermatid development)|go:""GO:0007338""(single fertilization)|go:""GO:0007566""(embryo implantation)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008584""(male gonad development)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030527""(structural constituent of chromatin)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0031508""(pericentric heterochromatin formation)|go:""GO:0031509""(subtelomeric heterochromatin formation)|go:""GO:0032200""(telomere organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090230""(regulation of centromere complex assembly)|go:""GO:1902340""(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|rcsb pdb:3QL9|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:3WTP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4GNG|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4U7T|rcsb pdb:4W5A|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7CWH|rcsb pdb:7OKP|rcsb pdb:7V1L|rcsb pdb:7V1M|rcsb pdb:7VCQ|rcsb pdb:7W5M|rcsb pdb:7WBV|rcsb pdb:7WBW|rcsb pdb:7WBX|rcsb pdb:7XSE|rcsb pdb:7XSX|rcsb pdb:7XSZ|rcsb pdb:7XT7|rcsb pdb:7XTD|rcsb pdb:7XTI|rcsb pdb:8JH2|rcsb pdb:8JH3|rcsb pdb:8JH4|rcsb pdb:8KB5|rcsb pdb:9B3P|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-68616|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-9821002|reactome:R-HSA-9821993|reactome:R-HSA-983231|reactome:R-HSA-9841922|reactome:R-HSA-9843940|reactome:R-HSA-9843970|reactome:R-HSA-9845323|panther:PTHR11426(orthology-group)|ensembl:ENSP00000254810.3|ensembl:ENSP00000355778.1|ensembl:ENSP00000355780.3|ensembl:ENSP00000355781.1|ensembl:ENSP00000466020.1|ensembl:ENSP00000468714.1|ensembl:ENSP00000465813.1|ensembl:ENSP00000499800.1|ensembl:ENSP00000499385.1|ensembl:ENSP00000499275.1"	"go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0004568""(chitinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR029070|refseq:YP_169730.1|interpro:IPR003610(Carbohydrate-binding family V/XII)|interpro:IPR011583(Chitinase II)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_003020524.1|interpro:IPR036116|interpro:IPR036573|interpro:IPR050314"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606	rogid:hPHdF34TD5FCXE5bWyEmg/dd7sg177416	intact-crc:4319AA42BAF96F0E|rigid:aYv5mAuAh/M9fMn9lM6GeUl79P0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZM5	uniprotkb:Q5NEP4	intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802.4	intact:EBI-2802121|uniprotkb:A0A0G2RNJ4	psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym)	psi-mi:q5nep4_fratt(display_long)|uniprotkb:FTT_1576(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806460|imex:IM-13779-1033	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056525.2|ensembl:ENSG00000105373.19(gene)|ensembl:ENST00000246802.10(transcript)|go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002039""(p53 binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006364""(rRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0008097""(5S rRNA binding)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0039535""(regulation of RIG-I signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050821""(protein stabilization)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1901797""(negative regulation of signal transduction by p53 class mediator)|go:""GO:1901837""(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1902570""(protein localization to nucleolus)|go:""GO:1903006""(positive regulation of protein K63-linked deubiquitination)|go:""GO:1903715""(regulation of aerobic respiration)|go:""GO:1990173""(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|rcsb pdb:8FKZ|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR3|panther:PTHR14211(orthology-group)"	"refseq:YP_170498.1|refseq:WP_003022484.1|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606	rogid:qivaxTncNwJ4rDFodbXHR2exiRI177416	intact-crc:3AAE72F6733AB165|rigid:ewSpmN9dkfXtzQvQMhxv6wKN1V8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGM1	uniprotkb:P09211	intact:EBI-2806450	intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607.3|uniprotkb:Q5TZY3	psi-mi:q5ngm1_fratt(display_long)|uniprotkb:FTT_0814c(locus name)	psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806453|imex:IM-13779-1035	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"refseq:NP_000843.1|ensembl:ENSG00000084207.18(gene)|ensembl:ENST00000398606.10(transcript)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0002674""(negative regulation of acute inflammatory response)|go:""GO:0004364""(glutathione transferase activity)|go:""GO:0004602""(glutathione peroxidase activity)|go:""GO:0005504""(fatty acid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006693""(prostaglandin metabolic process)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0007417""(central nervous system development)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0009890""(negative regulation of biosynthetic process)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0019207""(kinase regulator activity)|go:""GO:0031982""(vesicle)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0032873""(negative regulation of stress-activated MAPK cascade)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0035730""(S-nitrosoglutathione binding)|go:""GO:0035731""(dinitrosyl-iron complex binding)|go:""GO:0035732""(nitric oxide storage)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043508""(negative regulation of JUN kinase activity)|go:""GO:0043651""(linoleic acid metabolic process)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0051122""(hepoxilin biosynthetic process)|go:""GO:0051771""(obsolete negative regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0070026""(nitric oxide binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070664""(negative regulation of leukocyte proliferation)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071638""(negative regulation of monocyte chemotactic protein-1 production)|go:""GO:0097057""(TRAF2-GSTP1 complex)|go:""GO:1901687""(glutathione derivative biosynthetic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|interpro:IPR050213|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7BIA|rcsb pdb:7GSS|rcsb pdb:7XBA|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9753281|panther:PTHR11571(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5hVNwHSShfqXYsi7XjaiaBE93cI177416	rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606	intact-crc:ECA535FEFB30BC2F|rigid:OxfdEh0s0WMovK6BFi0WZ1Wvufk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P78347	uniprotkb:Q5NHM9	intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070.1	intact:EBI-2800895	psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym)	psi-mi:q5nhm9_fratt(display_long)|uniprotkb:glyQ(gene name)|psi-mi:glyQ(display_short)|uniprotkb:Glycyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:FTT_0419(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806443|imex:IM-13779-1032	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:904""|ensembl:ENSG00000263001.8(gene)|ensembl:ENST00000573035.6(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|interpro:IPR036647|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|refseq:NP_001157108.1|refseq:NP_001267729.1|refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|dip:DIP-24252N|panther:PTHR46304(orthology-group)"	"interpro:IPR006194(Glycyl-tRNA synthetase, class II, heterodimeric)|interpro:IPR002310(Glycyl-tRNA synthetase, class IIc, alpha subunit)|refseq:YP_169463.1|go:""GO:0004820""(glycine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006426""(glycyl-tRNA aminoacylation)|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606	rogid:gK04DTuny1DO8Bpf570jc75RJkg177416	intact-crc:A655C0DD4FC3ECF1|rigid:By97m2evvptSBeAKlNZoHuATu0E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF37	uniprotkb:P78347	intact:EBI-2798724	intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070.1	psi-mi:syp_fratt(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1412(locus name)	psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806436|imex:IM-13779-1034	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044140|refseq:YP_170355.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|interpro:IPR033730|refseq:WP_003022224.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR045864|interpro:IPR050062"	"efo:""Orphanet:904""|ensembl:ENSG00000263001.8(gene)|ensembl:ENST00000573035.6(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|interpro:IPR036647|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|refseq:NP_001157108.1|refseq:NP_001267729.1|refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|dip:DIP-24252N|panther:PTHR46304(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6/QkU5JRWJEBZMwaR9J83no0ffk177416	rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606	intact-crc:C38F6EDD4CFFCAD1|rigid:kHjhtUZqqnNOHzf1BEVGfkMRyJQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:P09341	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-2806484|uniprotkb:Q9UCR7|ensembl:ENSP00000379110.3	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:groa_human(display_long)|uniprotkb:GRO(gene name synonym)|uniprotkb:GRO1(gene name synonym)|uniprotkb:GROA(gene name synonym)|uniprotkb:MGSA(gene name synonym)|uniprotkb:SCYB1(gene name synonym)|uniprotkb:C-X-C motif chemokine 1(gene name synonym)|uniprotkb:""GRO-alpha(1-73)""(gene name synonym)|uniprotkb:Melanoma growth stimulatory activity(gene name synonym)|uniprotkb:Neutrophil-activating protein 3(gene name synonym)|uniprotkb:CXCL1(gene name)|psi-mi:CXCL1(display_short)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806489|imex:IM-13779-1039	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"refseq:NP_001502.1|ensembl:ENSG00000163739.5(gene)|ensembl:ENST00000395761.4(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008009""(chemokine activity)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008083""(growth factor activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035580""(specific granule lumen)|go:""GO:0045236""(CXCR chemokine receptor binding)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:1904724""(tertiary granule lumen)|interpro:IPR001089(Small chemokine, C-X-C)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR018048|interpro:IPR033899|interpro:IPR036048|interpro:IPR039809|mint:P09341|rcsb pdb:1MGS|rcsb pdb:1MSG|rcsb pdb:1MSH|rcsb pdb:1ROD|rcsb pdb:8K4O|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|reactome:R-HSA-6798695|dip:DIP-5896N|panther:PTHR12015(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:G1FjJPmJmTihQqinvYHGXwxJEkY9606	intact-crc:0C4B462E33F2CD5A|rigid:GY3wwBX8CVjWuJ08xp4Ko0zYuU8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z6J2	uniprotkb:Q5NHN0	intact:EBI-2806496|uniprotkb:Q7Z741|uniprotkb:Q6PIF8|ensembl:ENSP00000293662.4	intact:EBI-2801077|uniprotkb:A0A0G2RME2	psi-mi:grasp_human(display_long)|uniprotkb:TAMALIN(gene name)|psi-mi:TAMALIN(display_short)|uniprotkb:GRASP(gene name synonym)|uniprotkb:General receptor for phosphoinositides 1-associated scaffold protein(gene name synonym)	psi-mi:q5nhn0_fratt(display_long)|uniprotkb:malA(gene name)|psi-mi:malA(display_short)|uniprotkb:Amylomaltase(gene name synonym)|uniprotkb:Disproportionating enzyme(gene name synonym)|uniprotkb:FTT_0418(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806502|imex:IM-13779-1037	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_859062.1|refseq:NP_001258785.1|ensembl:ENSG00000161835.11(gene)|ensembl:ENST00000293662.9(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0014069""(postsynaptic density)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR052122|rcsb pdb:2PNT|panther:PTHR15963(orthology-group)"	"interpro:IPR003385(Glycoside hydrolase, family 77)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:YP_169462.1|go:""GO:0004134""(4-alpha-glucanotransferase activity)|go:""GO:0005975""(carbohydrate metabolic process)|refseq:WP_003028948.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:g5tlWq39uCpqy44+ohXeLCj2t0E9606	rogid:a08r9HjqCaJhW+SGa68Utfl1cGQ177416	intact-crc:CD8D30D747701DCD|rigid:GD9XrXOr+kflRFLr/wV4NFY1nEU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZM4	uniprotkb:Q5NHB4	intact:EBI-1754943|uniprotkb:A8MW01|ensembl:ENSP00000379946.2|ensembl:ENSP00000469738.2|intact:EBI-28975771	intact:EBI-2806470|uniprotkb:A0A0G2RNP6	psi-mi:bicra_human(display_long)|uniprotkb:BICRA(gene name)|psi-mi:BICRA(display_short)|uniprotkb:GLTSCR1(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 1 protein(gene name synonym)	psi-mi:q5nhb4_fratt(display_long)|uniprotkb:FTT_0552(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806467|imex:IM-13779-1038	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056526.3|refseq:XP_005258890.1|ensembl:ENSG00000063169.12(gene)|ensembl:ENST00000396720.7(transcript)|ensembl:ENST00000594866.3(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140288""(GBAF complex)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR015671(Glioma tumour suppressor candidate region gene 1)|interpro:IPR052438|mint:Q9NZM4|panther:PTHR15572(orthology-group)"	"interpro:IPR044638|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|refseq:YP_169578.1|go:""GO:0004029""(""aldehyde dehydrogenase (NAD+) activity"")|interpro:IPR029510|refseq:WP_003023258.1|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iJokFxqZtCvuWinjN0DR51nuMQU9606	rogid:Rv5E1n7vpKC1OT8ELP/7+ufCueY177416	intact-crc:082DB6F50D4232EF|rigid:bbg47EMiQKlD9OBsTFvZnmYIyFs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF52	uniprotkb:Q7LDG7	intact:EBI-2801584|uniprotkb:A0A0G2RNY6	intact:EBI-722325|uniprotkb:O00538|uniprotkb:Q9UL65|uniprotkb:A6NDC7|ensembl:ENSP00000338864.3|ensembl:ENSP00000366717.3|ensembl:ENSP00000377953.3	psi-mi:q5nf52_fratt(display_long)|uniprotkb:FTT_1395c(locus name)	psi-mi:grp2_human(display_long)|uniprotkb:CDC25L(gene name synonym)|uniprotkb:MCG7(gene name synonym)|uniprotkb:Calcium and DAG-regulated guanine nucleotide exchange factor I(gene name synonym)|uniprotkb:F25B3.3 kinase-like protein(gene name synonym)|uniprotkb:Cdc25-like protein(gene name synonym)|uniprotkb:RASGRP2(gene name)|psi-mi:RASGRP2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806477|imex:IM-13779-1036	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007421(ATPase associated with various cellular activities, AAA-4)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:YP_170340.1|interpro:IPR025831|go:""GO:0004386""(helicase activity)|refseq:WP_003022198.1|interpro:IPR038461|interpro:IPR038475|interpro:IPR036388|interpro:IPR036390"	"efo:""Orphanet:420566""|ensembl:ENSG00000068831.19(gene)|ensembl:ENST00000354024.7(transcript)|ensembl:ENST00000377497.7(transcript)|ensembl:ENST00000394432.8(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0008289""(lipid binding)|go:""GO:0019992""(diacylglycerol binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0043005""(neuron projection)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045202""(synapse)|go:""GO:0071277""(cellular response to calcium ion)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR023578|interpro:IPR036964|interpro:IPR046349|rcsb pdb:2MA2|rcsb pdb:6AXF|reactome:R-HSA-114508|reactome:R-HSA-2871837|reactome:R-HSA-354192|reactome:R-HSA-392517|refseq:NP_001092140.1|refseq:NP_001092141.1|refseq:NP_001305327.1|refseq:NP_722541.1|refseq:XP_011543022.1|refseq:XP_011543023.1|refseq:XP_011543024.1|refseq:XP_011543025.1|refseq:XP_016872573.1|panther:PTHR23113(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jXG9mH+7eRZFsFBHYoB3CjJacm0177416	rogid:bLHmFJ6tkO2Vqy0Qi1MmJSuJ+Po9606	intact-crc:885D246DE4AC2BCE|rigid:dfKUkzGxCtgQdzUeh/kjlrUksxE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86XS8	uniprotkb:Q5NI89	intact:EBI-719861|uniprotkb:Q32P32|uniprotkb:Q641P9|uniprotkb:Q6P177|uniprotkb:Q7L2U2|uniprotkb:Q9P0J9|ensembl:ENSP00000430237.1|intact:EBI-2129193|uniprotkb:J3KN31|uniprotkb:Q59EL1	intact:EBI-2796250	psi-mi:goli_human(display_long)|uniprotkb:RING finger protein 130(gene name synonym)|uniprotkb:RNF130(gene name)|psi-mi:RNF130(display_short)|uniprotkb:Goliath homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF130(gene name synonym)	psi-mi:q5ni89_fratt(display_long)|uniprotkb:lysS(gene name synonym)|uniprotkb:lysU(gene name)|psi-mi:lysU(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0192(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806527|imex:IM-13779-1043	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001267730.1|refseq:NP_060904.2|ensembl:ENSG00000113269.14(gene)|ensembl:ENST00000521389.6(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR046450|interpro:IPR051834|mint:Q86XS8|reactome:R-HSA-983168|panther:PTHR22765(orthology-group)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|interpro:IPR044136|refseq:YP_169253.1|interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OpFZYE55FFPN28YeaGOPtm4HFIc9606	rogid:4e6LdrlEB4PMi+b0yLmkVagonC4177416	intact-crc:76EC0E621B028E40|rigid:fHFvAWs47wIMf78WZUdPErWr658	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEP4	uniprotkb:Q8TDU6	intact:EBI-2802121|uniprotkb:A0A0G2RNJ4	intact:EBI-2806519|uniprotkb:B3KV35|ensembl:ENSP00000428824.1|ensembl:ENSP00000430202.1|ensembl:ENSP00000430698.1|ensembl:ENSP00000430886.1	psi-mi:q5nep4_fratt(display_long)|uniprotkb:FTT_1576(locus name)	psi-mi:gpbar_human(display_long)|uniprotkb:TGR5(gene name synonym)|uniprotkb:G-protein coupled receptor GPCR19(gene name synonym)|uniprotkb:Membrane-type receptor for bile acids(gene name synonym)|uniprotkb:hBG37(gene name synonym)|uniprotkb:GPBAR1(gene name)|psi-mi:GPBAR1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806516|imex:IM-13779-1040	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_170498.1|refseq:WP_003022484.1|go:""GO:0016020""(membrane)"	"refseq:XP_011509045.1|refseq:NP_001070659.1|refseq:NP_001070662.1|refseq:NP_733800.1|refseq:NP_001308879.1|ensembl:ENSG00000179921.15(gene)|ensembl:ENST00000479077.5(transcript)|ensembl:ENST00000519574.2(transcript)|ensembl:ENST00000521462.1(transcript)|ensembl:ENST00000522678.5(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0038182""(G protein-coupled bile acid receptor activity)|go:""GO:0038184""(adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway)|go:""GO:0043235""(receptor complex)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:1903413""(cellular response to bile acid)|go:""GO:1904056""(positive regulation of cholangiocyte proliferation)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q8TDU6|rcsb pdb:7BW0|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7XTQ|rcsb pdb:9GYO|reactome:R-HSA-373076|reactome:R-HSA-418555|refseq:XP_016858958.1|refseq:XP_016858956.1|refseq:XP_016858957.1|panther:PTHR24246(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qivaxTncNwJ4rDFodbXHR2exiRI177416	rogid:o06hNOIJvAXLsQ46In25NnwRZOE9606	intact-crc:624647920215202D|rigid:5svSUEumMdEQpAzS4KCuWru7Ee8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P12544	uniprotkb:Q5NEC0	intact:EBI-519800|uniprotkb:Q6IB36|uniprotkb:A4PHN1|ensembl:ENSP00000274306.6	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:graa_human(display_long)|uniprotkb:Granzyme-1(gene name synonym)|uniprotkb:Cytotoxic T-lymphocyte proteinase 1(gene name synonym)|uniprotkb:Hanukkah factor(gene name synonym)|uniprotkb:CTL tryptase(gene name synonym)|uniprotkb:Fragmentin-1(gene name synonym)|uniprotkb:GZMA(gene name)|psi-mi:GZMA(display_short)|uniprotkb:CTLA3(gene name synonym)|uniprotkb:HFSP(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806509|imex:IM-13779-1042	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006135.1|panther:PTHR24271(orthology-group)|ensembl:ENSG00000145649.8(gene)|ensembl:ENST00000274306.7(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0006955""(immune response)|go:""GO:0009617""(response to bacterium)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0032078""(negative regulation of endodeoxyribonuclease activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0051354""(negative regulation of oxidoreductase activity)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0051604""(protein maturation)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0140507""(granzyme-mediated programmed cell death signaling pathway)|go:""GO:1902483""(cytotoxic T cell pyroptotic cell death)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:1OP8|rcsb pdb:1ORF"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8ftirjCyo9Y60L7sWDoQmXIa+M49606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:C5F1EBCE5BFA7FAC|rigid:OMA7S7wnY7meNTcixmevPmiqg0w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI66	uniprotkb:Q86XS8	intact:EBI-2797252|uniprotkb:A0A0G2RM61	intact:EBI-719861|uniprotkb:Q32P32|uniprotkb:Q641P9|uniprotkb:Q6P177|uniprotkb:Q7L2U2|uniprotkb:Q9P0J9|ensembl:ENSP00000430237.1|intact:EBI-2129193|uniprotkb:J3KN31|uniprotkb:Q59EL1	psi-mi:q5ni66_fratt(display_long)|uniprotkb:acpA(gene name)|psi-mi:acpA(display_short)|uniprotkb:FTT_0221(locus name)	psi-mi:goli_human(display_long)|uniprotkb:RING finger protein 130(gene name synonym)|uniprotkb:RNF130(gene name)|psi-mi:RNF130(display_short)|uniprotkb:Goliath homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF130(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806534|imex:IM-13779-1041	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0034480""(phosphatidylcholine phospholipase C activity)|interpro:IPR007312(Phosphoesterase)|refseq:YP_169276.1|refseq:WP_003021808.1|interpro:IPR017850(Alkaline-phosphatase-like, core domain)"	"refseq:NP_001267730.1|refseq:NP_060904.2|ensembl:ENSG00000113269.14(gene)|ensembl:ENST00000521389.6(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR046450|interpro:IPR051834|mint:Q86XS8|reactome:R-HSA-983168|panther:PTHR22765(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4qC583ToLOkAvm3AlbzGYd39Rt8177416	rogid:OpFZYE55FFPN28YeaGOPtm4HFIc9606	intact-crc:7D420E621870A41D|rigid:vkD4w/tDpEDnVt6pe9vmb7KwNT4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NER2	uniprotkb:Q9P2T1	intact:EBI-2806544|uniprotkb:A0A0G2RNI1	intact:EBI-2806548|uniprotkb:Q567T0|uniprotkb:Q6IAJ8|uniprotkb:D3DS66|ensembl:ENSP00000347449.4|ensembl:ENSP00000382369.2|ensembl:ENSP00000453299.1|ensembl:ENSP00000494224.1|ensembl:ENSP00000495583.1|ensembl:ENSP00000496504.1|uniprotkb:Q86T14	psi-mi:q5ner2_fratt(display_long)|uniprotkb:lepB(gene name)|psi-mi:lepB(display_short)|uniprotkb:FTT_1556c(locus name)	psi-mi:gmpr2_human(display_long)|uniprotkb:Guanosine 5'-monophosphate oxidoreductase 2(gene name synonym)|uniprotkb:GMPR2(gene name)|psi-mi:GMPR2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806541|imex:IM-13779-1045	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000223(Peptidase S26A, signal peptidase I)|interpro:IPR019758|interpro:IPR019757|interpro:IPR019533|refseq:YP_170480.1|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006465""(signal peptide processing)|go:""GO:0016020""(membrane)|refseq:WP_003022453.1|interpro:IPR036286"	"refseq:NP_001269950.1|refseq:NP_001269951.1|refseq:NP_001269952.1|refseq:NP_001002000.1|refseq:NP_001002001.1|refseq:NP_001002002.1|refseq:NP_057660.2|ensembl:ENSG00000100938.19(gene)|ensembl:ENSG00000284752.3(gene)|ensembl:ENST00000355299.8(transcript)|ensembl:ENST00000399440.7(transcript)|ensembl:ENST00000559836.5(transcript)|ensembl:ENST00000642276.1(transcript)|ensembl:ENST00000644066.1(transcript)|ensembl:ENST00000647320.3(transcript)|go:""GO:0003920""(GMP reductase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006144""(purine nucleobase metabolic process)|go:""GO:0046037""(GMP metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:1902560""(GMP reductase complex)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005993(Guanosine monophosphate reductase 1)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|interpro:IPR050139|mint:Q9P2T1|rcsb pdb:2A7R|rcsb pdb:2BZN|rcsb pdb:2C6Q|reactome:R-HSA-74217|panther:PTHR43170(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0gRosROSex/pqXQY08vJ6+/PfJw177416	rogid:/k9kNXIA6CIiiNIhpdrXTrR5wE89606	intact-crc:1234DADBB97B7172|rigid:81mQEXFybyn9OxmRjiCg8li1o0o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15104	uniprotkb:Q5NII1	intact:EBI-746653|ensembl:ENSP00000307900.5|ensembl:ENSP00000344958.5|ensembl:ENSP00000356537.6|ensembl:ENSP00000398320.2|uniprotkb:Q499Y9|uniprotkb:Q5T9Z1|uniprotkb:Q7Z3W4|uniprotkb:Q8IZ17	intact:EBI-2797156|uniprotkb:A0A0G2RN00	psi-mi:glna_human(display_long)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:GLUL(gene name)|psi-mi:GLUL(display_short)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Palmitoyltransferase GLUL(gene name synonym)	psi-mi:q5nii1_fratt(display_long)|uniprotkb:acnA(gene name)|psi-mi:acnA(display_short)|uniprotkb:FTT_0087(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806558|imex:IM-13779-1044	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000135821.20(gene)|ensembl:ENST00000311223.9(transcript)|ensembl:ENST00000331872.11(transcript)|ensembl:ENST00000339526.9(transcript)|ensembl:ENST00000417584.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0004356""(glutamine synthetase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006538""(glutamate catabolic process)|go:""GO:0006542""(glutamine biosynthetic process)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009749""(response to glucose)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0018345""(protein palmitoylation)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0044297""(cell body)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097386""(glial cell projection)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1904749""(regulation of protein localization to nucleolus)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|interpro:IPR050292|mint:P15104|rcsb pdb:2OJW|rcsb pdb:2QC8|rcsb pdb:7EVT|rcsb pdb:8DNU|reactome:R-HSA-210455|reactome:R-HSA-8964539|refseq:NP_001028216.1|refseq:NP_001028228.1|refseq:NP_002056.2|refseq:XP_006711341.1|efo:""Orphanet:71278""|dip:DIP-308N|panther:PTHR20852(orthology-group)"	"go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR044137|refseq:YP_169161.1|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR018136|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|refseq:WP_003019815.1|interpro:IPR036008"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/22	rogid:UOOgfw1g+kmpsEx64pUbW9GfmYw9606	rogid:FGVUBUKOHsDquKU0LqPkXCpRg+o177416	intact-crc:F4500CB8D603998A|rigid:iiP1qFtGukwUY3BspsH20+vYSwc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14161	uniprotkb:Q5NH99	intact:EBI-1046878|uniprotkb:Q86U59|uniprotkb:Q96CI2|uniprotkb:Q9BV91|uniprotkb:Q9Y5V2|ensembl:ENSP00000347464.3	intact:EBI-2804100|uniprotkb:A0A0G2RQ01	psi-mi:git2_human(display_long)|uniprotkb:G protein-coupled receptor kinase-interactor 2(gene name synonym)|uniprotkb:GRK-interacting protein 2(gene name synonym)|uniprotkb:Cool-interacting tyrosine-phosphorylated protein 2(gene name synonym)|uniprotkb:GIT2(gene name)|psi-mi:GIT2(display_short)|uniprotkb:KIAA0148(gene name synonym)	psi-mi:q5nh99_fratt(display_long)|uniprotkb:FTT_0568(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806565|imex:IM-13779-1046	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000139436.22(gene)|ensembl:ENST00000355312.8(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0007420""(brain development)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032012""(regulation of ARF protein signal transduction)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:0098793""(presynapse)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724(""Spa2 homology (SHD) of GIT"")|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|interpro:IPR047161|mint:Q14161|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|refseq:NP_001128685.1|refseq:NP_001128686.1|refseq:NP_055591.2|refseq:NP_476510.1|refseq:NP_476511.1|refseq:XP_006719770.1|refseq:XP_006719772.1|refseq:NP_001317082.1|panther:PTHR46097(orthology-group)"	"interpro:IPR023214|refseq:YP_169593.1|rcsb pdb:3KD3|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006564""(L-serine biosynthetic process)|go:""GO:0036424""(L-phosphoserine phosphatase activity)|refseq:WP_003023286.1|interpro:IPR036412|interpro:IPR050582"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Zy6G7UFDxfCVVUEHq44V37dWekw9606	rogid:JbFnfJ9+9d8sJPItg7j1yZOLkXw177416	intact-crc:E46D59A1345467DA|rigid:t3rT9Us+FCfe0NkPrA6E12upsOA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEL1	uniprotkb:O14908	intact:EBI-2805325	intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|ensembl:ENSP00000340698.1|ensembl:ENSP00000376753.3|ensembl:ENSP00000466747.1|uniprotkb:A8K4I3	psi-mi:syc_fratt(display_long)|uniprotkb:Cysteinyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1616(locus name)|uniprotkb:cysS(gene name)|psi-mi:cysS(display_short)	psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806603|imex:IM-13779-1050	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015803(Cysteinyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015273(Cysteinyl-tRNA synthetase, class Ia, DALR)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|refseq:YP_170531.1|interpro:IPR024909|go:""GO:0004817""(cysteine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006423""(cysteinyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|interpro:IPR032678|refseq:WP_003022540.1"	"panther:PTHR12259(orthology-group)|ensembl:ENSG00000123159.16(gene)|ensembl:ENST00000345425.6(transcript)|ensembl:ENST00000393033.9(transcript)|ensembl:ENST00000586027.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0006605""(protein targeting)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0008021""(synaptic vesicle)|efo:""Orphanet:98897""|go:""GO:0012506""(vesicle membrane)|go:""GO:0014047""(glutamate secretion)|go:""GO:0016020""(membrane)|go:""GO:0017022""(myosin binding)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0045296""(cadherin binding)|go:""GO:0048023""(positive regulation of melanin biosynthetic process)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099171""(presynaptic modulation of chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|mint:O14908|reactome:R-HSA-190370|reactome:R-HSA-190373|reactome:R-HSA-9839389|reactome:R-HSA-9839397|refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974198.1|refseq:NP_974199.1|refseq:NP_974223.1|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/17	rogid:pMiIpqmMZZrK8RXU9FBTTYhN2QQ177416	rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606	intact-crc:712A282193066DF9|rigid:tMo1vEpqE4SDI9aAU4Rb6DA483w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHH1	uniprotkb:Q9Y2X7	intact:EBI-2806572|uniprotkb:A0A0G2RNX4	intact:EBI-466061|uniprotkb:Q86SS0|uniprotkb:Q9BRJ4|uniprotkb:B4DSV3|uniprotkb:B4DGU9|ensembl:ENSP00000225394.3	psi-mi:q5nhh1_fratt(display_long)|uniprotkb:rsgA(gene name)|psi-mi:rsgA(display_short)|uniprotkb:FTT_0483c(locus name)	psi-mi:git1_human(display_long)|uniprotkb:GIT1(gene name)|psi-mi:GIT1(display_short)|uniprotkb:G protein-coupled receptor kinase-interactor 1(gene name synonym)|uniprotkb:GRK-interacting protein 1(gene name synonym)|uniprotkb:Cool-associated and tyrosine-phosphorylated protein 1(gene name synonym)|uniprotkb:p95-APP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806575|imex:IM-13779-1047	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010914(EngC GTPase)|interpro:IPR004881(GTPase EngC)|refseq:YP_169521.1|interpro:IPR027417|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0019843""(rRNA binding)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0046872""(metal ion binding)|interpro:IPR030378|refseq:WP_003020294.1"	"refseq:NP_001078923.1|refseq:NP_054749.2|ensembl:ENSG00000108262.16(gene)|ensembl:ENST00000225394.8(transcript)|go:""GO:0001957""(intramembranous ossification)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007420""(brain development)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032012""(regulation of ARF protein signal transduction)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0043005""(neuron projection)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0044305""(calyx of Held)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045202""(synapse)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045820""(negative regulation of glycolytic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048666""(neuron development)|go:""GO:0061743""(motor learning)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:0097431""(mitotic spindle pole)|go:""GO:0098794""(postsynapse)|go:""GO:0099171""(presynaptic modulation of chemical synaptic transmission)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724(""Spa2 homology (SHD) of GIT"")|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|interpro:IPR047161|mint:Q9Y2X7|reactome:R-HSA-3928664|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9619229|panther:PTHR46097(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JDJJjcCcGFnk5vEyMqH2O5abyCw177416	rogid:9POm+EVvD4/BQh6bApnpXCAZyZo9606	intact-crc:68ABEBEC4B19A5BB|rigid:DJtMrigmGfX3qx2UiBrKZOz82Z0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TF65	uniprotkb:Q5NEN3	intact:EBI-712067|uniprotkb:Q8IYD3|uniprotkb:Q9NXS7|ensembl:ENSP00000359795.3	intact:EBI-2806593	psi-mi:gipc2_human(display_long)|uniprotkb:GIPC2(gene name)|psi-mi:GIPC2(display_short)	psi-mi:q5nen3_fratt(display_long)|uniprotkb:FTT_1591(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806596|imex:IM-13779-1048	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137960.6(gene)|ensembl:ENST00000370759.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|mint:Q8TF65|rcsb pdb:3GGE|refseq:NP_060125.4|refseq:NP_001291654.1|panther:PTHR12259(orthology-group)"	"interpro:IPR007428(VacJ-like lipoprotein)|refseq:YP_170509.1|go:""GO:0016020""(membrane)|go:""GO:0120010""(intermembrane phospholipid transfer)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tmXszDsKNzUfki6x7swoLDtaow89606	rogid:nuOlvTUFuKENrRhUMqrKgIrW+Yo177416	intact-crc:A521C3816FCEF8BC|rigid:Z3iUsiE0eKWooppZ7/yN69Ivb0M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TF65	uniprotkb:Q5NI92	intact:EBI-712067|uniprotkb:Q8IYD3|uniprotkb:Q9NXS7|ensembl:ENSP00000359795.3	intact:EBI-2806582	psi-mi:gipc2_human(display_long)|uniprotkb:GIPC2(gene name)|psi-mi:GIPC2(display_short)	psi-mi:lpxc_fratt(display_long)|uniprotkb:lpxC(gene name)|psi-mi:lpxC(display_short)|uniprotkb:UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase(gene name synonym)|uniprotkb:FTT_0189(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806586|imex:IM-13779-1049	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137960.6(gene)|ensembl:ENST00000370759.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|mint:Q8TF65|rcsb pdb:3GGE|refseq:NP_060125.4|refseq:NP_001291654.1|panther:PTHR12259(orthology-group)"	"interpro:IPR020568|interpro:IPR004463(UDP-3-O-acyl N-acetylglucosamine deacetylase)|interpro:IPR011334(UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal)|interpro:IPR015870(UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal)|refseq:YP_169250.1|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0103117""(UDP-3-O-acyl-N-acetylglucosamine deacetylase activity)|refseq:WP_003017478.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tmXszDsKNzUfki6x7swoLDtaow89606	rogid:E7iyDSRZdrLrWX+lZzZpTb2uuUM177416	intact-crc:08B88F816F816284|rigid:8q3yCHVxkE8uOuZtcIX9usAs0S0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID1	uniprotkb:Q96CW5	intact:EBI-2796238	intact:EBI-1046278|uniprotkb:O43631|uniprotkb:O60852|uniprotkb:O60853|uniprotkb:Q7Z4K1|uniprotkb:Q96I79|uniprotkb:Q5T8L2|ensembl:ENSP00000261965.3	psi-mi:rpoc_fratt(display_long)|uniprotkb:RNA polymerase subunit beta'(gene name synonym)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:FTT_0145(locus name)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)	psi-mi:gcp3_human(display_long)|uniprotkb:Spindle pole body protein Spc98 homolog(gene name synonym)|uniprotkb:TUBGCP3(gene name)|psi-mi:TUBGCP3(display_short)|uniprotkb:GCP3(gene name synonym)|uniprotkb:Gamma-ring complex protein 104 kDa(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806636|imex:IM-13779-1054	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000287""(magnesium ion binding)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0008270""(zinc ion binding)|interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|refseq:YP_169211.1|refseq:WP_003019910.1|interpro:IPR038120|interpro:IPR044893|interpro:IPR045867|interpro:IPR042102"	"refseq:NP_006313.1|refseq:NP_001273207.1|refseq:NP_001273208.1|refseq:NP_001273206.1|ensembl:ENSG00000126216.15(gene)|ensembl:ENST00000261965.8(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000930""(gamma-tubulin complex)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005819""(spindle)|go:""GO:0005827""(polar microtubule)|go:""GO:0005829""(cytosol)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007338""(single fertilization)|go:""GO:0016020""(membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051321""(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q96CW5|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0U|rcsb pdb:7AS4|rcsb pdb:7QJ0|rcsb pdb:7QJ1|rcsb pdb:7QJ2|rcsb pdb:7QJ3|rcsb pdb:7QJ4|rcsb pdb:7QJ5|rcsb pdb:7QJ6|rcsb pdb:7QJ7|rcsb pdb:7QJ8|rcsb pdb:7QJ9|rcsb pdb:7QJA|rcsb pdb:7QJB|rcsb pdb:7QJC|rcsb pdb:7QJD|rcsb pdb:8Q62|rcsb pdb:8RX1|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|reactome:R-HSA-380270|reactome:R-HSA-380320|panther:PTHR19302(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nCrO43u1Xg+RCZk3AEfSW6oQCNA177416	rogid:xt+Ngo2s/4djh2PnyMEaxgDyLrs9606	intact-crc:A83EC940936384B8|rigid:i9avDrGWvaURE7Bc+kY3UsUPl/Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NG28	uniprotkb:P52566	intact:EBI-2802768|uniprotkb:A0A0G2RPI9	intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945.4|ensembl:ENSP00000440560.1|ensembl:ENSP00000444860.1	psi-mi:q5ng28_fratt(display_long)|uniprotkb:dacD(gene name)|psi-mi:dacD(display_short)|uniprotkb:FTT_1029(locus name)	psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806629|imex:IM-13779-1052	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015956(Penicillin-binding protein-associated)|interpro:IPR018044|interpro:IPR012907(Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal)|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:YP_170014.1|refseq:WP_003021136.1|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|rcsb pdb:6OSU|mint:Q5NG28|interpro:IPR037167"	"refseq:NP_001166.3|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|ensembl:ENSG00000111348.9(gene)|ensembl:ENST00000228945.9(transcript)|ensembl:ENST00000541546.5(transcript)|ensembl:ENST00000541644.5(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005094""(Rho GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071461""(cellular response to redox state)|go:""GO:1901164""(negative regulation of trophoblast cell migration)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|dip:DIP-40959N|panther:PTHR10980(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EYTPcD8JUkej9Gvps0ogQD5aQ1c177416	rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606	intact-crc:A25D6D2507B7AB35|rigid:+aRLwMAHTm863X9bZ4OEYkFy4tU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8G8T7	uniprotkb:P52566	intact:EBI-2796603	intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945.4|ensembl:ENSP00000440560.1|ensembl:ENSP00000444860.1	psi-mi:q8g8t7_fratl(display_long)|uniprotkb:asd(gene name)|psi-mi:asd(display_short)	psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806622|imex:IM-13779-1053	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004073""(aspartate-semialdehyde dehydrogenase activity)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0009088""(threonine biosynthetic process)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0019877""(diaminopimelate biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_003020169.1|interpro:IPR000319(Aspartate-semialdehyde dehydrogenase, conserved site)|interpro:IPR011534(Aspartate-semialdehyde dehydrogenase, proteobacteria)|interpro:IPR000534(Semialdehyde dehydrogenase, NAD-binding)|interpro:IPR012280(Semialdehyde dehydrogenase, dimerisation region)|rcsb pdb:4WOJ|interpro:IPR036291"	"refseq:NP_001166.3|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|ensembl:ENSG00000111348.9(gene)|ensembl:ENST00000228945.9(transcript)|ensembl:ENST00000541546.5(transcript)|ensembl:ENST00000541644.5(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005094""(Rho GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071461""(cellular response to redox state)|go:""GO:1901164""(negative regulation of trophoblast cell migration)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|dip:DIP-40959N|panther:PTHR10980(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HbI1K+KPeND7CwD3y7jf62tQ4ZA119856	rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606	intact-crc:A876C19F39D048CE|rigid:lBFq5HDe7bYBWMw65v0N6+0O2rU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEB2	uniprotkb:Q9HCC8	intact:EBI-2798884|uniprotkb:A0A0G2RQ36	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	psi-mi:q5neb2_fratt(display_long)|uniprotkb:nhaD(gene name)|psi-mi:nhaD(display_short)|uniprotkb:FTT_1728(locus name)	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806610|imex:IM-13779-1051	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004680(Divalent ion symporter)|refseq:YP_170630.1|go:""GO:0006814""(sodium ion transport)|go:""GO:0015297""(antiporter activity)|go:""GO:0016020""(membrane)|refseq:WP_003022705.1|interpro:IPR045016"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dMkzLU8Z52Olqw/ME0r9WHTAxs4177416	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	intact-crc:0DF6578406CB3323|rigid:OIxqbnKk6OtdzKIOAqrTe5IuR9Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF74	uniprotkb:P63244	intact:EBI-2796785|uniprotkb:A0A0G2RND4	intact:EBI-296739|uniprotkb:P25388|ensembl:ENSP00000426909.1|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	psi-mi:rack1_human(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Receptor of activated protein C kinase 1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806657|imex:IM-13779-1056	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"ensembl:ENSG00000204628.12(gene)|ensembl:ENST00000512805.6(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007369""(gastrulation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015935""(small ribosomal subunit)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030332""(cyclin binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042998""(positive regulation of Golgi to plasma membrane protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043204""(perikaryon)|go:""GO:0043473""(pigmentation)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045296""(cadherin binding)|refseq:NP_006089.1|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048511""(rhythmic process)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051901""(positive regulation of mitochondrial depolarization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0106070""(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:1900102""(negative regulation of endoplasmic reticulum unfolded protein response)|go:""GO:1903751""(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:1990630""(IRE1-RACK1-PP2A complex)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000543""(positive regulation of gastrulation)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001125""(negative regulation of translational frameshifting)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR045223|mint:P63244|rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|dip:DIP-46736N|panther:PTHR19868(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	intact-crc:C6D3060BBC041725|rigid:uQ8HUWOsIkorXed+YwSIgcnCGmk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96CN9	uniprotkb:Q5NGN5	intact:EBI-746252|ensembl:ENSP00000318821.2|uniprotkb:Q9H6N7	intact:EBI-2802385|uniprotkb:A0A0G2RN04	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	psi-mi:q5ngn5_fratt(display_long)|uniprotkb:FTT_0800(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806650|imex:IM-13779-1057	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000179562.3(gene)|ensembl:ENST00000321407.3(transcript)|go:""GO:0000138""(Golgi trans cisterna)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0031267""(small GTPase binding)|interpro:IPR000237(GRIP)|interpro:IPR051952|mint:Q96CN9|reactome:R-HSA-6811440|refseq:NP_078799.2|panther:PTHR23157(orthology-group)"	"interpro:IPR023214|interpro:IPR010237(Pyrimidine 5-nucleotidase)|refseq:YP_169807.1|refseq:WP_003016697.1|go:""GO:0006206""(pyrimidine nucleobase metabolic process)|go:""GO:0008252""(nucleotidase activity)|go:""GO:0009166""(nucleotide catabolic process)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR036412|interpro:IPR052791"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	rogid:aJGffcdVmrU1Zf5yHY+BtvWynz8177416	intact-crc:7A8DAEE4E4227E76|rigid:s+G55bCagvdgkEkMl5ulasl4B48	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96CN9	uniprotkb:Q5NIL8	intact:EBI-746252|ensembl:ENSP00000318821.2|uniprotkb:Q9H6N7	intact:EBI-2797707|uniprotkb:A0A0G2RN29	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	psi-mi:q5nil8_fratt(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:FTT_0049(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806643|imex:IM-13779-1055	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000179562.3(gene)|ensembl:ENST00000321407.3(transcript)|go:""GO:0000138""(Golgi trans cisterna)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0031267""(small GTPase binding)|interpro:IPR000237(GRIP)|interpro:IPR051952|mint:Q96CN9|reactome:R-HSA-6811440|refseq:NP_078799.2|panther:PTHR23157(orthology-group)"	"go:""GO:0000166""(nucleotide binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|refseq:YP_169124.1|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010214(Transcription termination factor NusA, C-terminal duplication)|interpro:IPR010213(Transcription termination factor NusA)|interpro:IPR025249|interpro:IPR030842|refseq:WP_003019733.1|interpro:IPR036555"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	rogid:h3B/JHGk+VSXL6iylODRYTPeDAc177416	intact-crc:594B00E4E7EA3DF2|rigid:+7Y+ugUwYm0bb4jCxCYYqx9U7Jk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHX0	uniprotkb:P63244	intact:EBI-2799263	intact:EBI-296739|uniprotkb:P25388|ensembl:ENSP00000426909.1|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	psi-mi:efg_fratt(display_long)|uniprotkb:FTT_0323(locus name)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)	psi-mi:rack1_human(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Receptor of activated protein C kinase 1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806664|imex:IM-13779-1058	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169372.1|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR031157|refseq:WP_003028885.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|interpro:IPR047872"	"ensembl:ENSG00000204628.12(gene)|ensembl:ENST00000512805.6(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007369""(gastrulation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015935""(small ribosomal subunit)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030332""(cyclin binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042998""(positive regulation of Golgi to plasma membrane protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043204""(perikaryon)|go:""GO:0043473""(pigmentation)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045296""(cadherin binding)|refseq:NP_006089.1|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048511""(rhythmic process)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051901""(positive regulation of mitochondrial depolarization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0106070""(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:1900102""(negative regulation of endoplasmic reticulum unfolded protein response)|go:""GO:1903751""(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:1990630""(IRE1-RACK1-PP2A complex)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000543""(positive regulation of gastrulation)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001125""(negative regulation of translational frameshifting)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR045223|mint:P63244|rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|dip:DIP-46736N|panther:PTHR19868(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:hULyXsLqQVOFqECbDOTlNV2kzrY177416	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	intact-crc:7368A80BBD63A734|rigid:Cha0ejEbMG6Q0MWS4vVvRde3fXk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NG02	uniprotkb:O60861	intact:EBI-2806685	intact:EBI-2683717|uniprotkb:Q53Y77|uniprotkb:B2RCK9|uniprotkb:Q7Z571|uniprotkb:O43144|uniprotkb:A8KAC2|ensembl:ENSP00000407552.2	psi-mi:q5ng02_fratt(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:FTT_1059c(locus name)	psi-mi:gas7_human(display_long)|uniprotkb:KIAA0394(gene name synonym)|uniprotkb:GAS7(gene name)|psi-mi:GAS7(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806689|imex:IM-13779-1062	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|refseq:YP_170040.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0006269""(DNA replication, synthesis of primer)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990077""(primosome complex)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR036185"	"refseq:XP_011522346.1|refseq:NP_003635.2|refseq:NP_958836.1|refseq:NP_958839.1|refseq:NP_001124303.1|refseq:XP_005256888.1|refseq:XP_005256889.1|refseq:XP_016880728.1|ensembl:ENSG00000007237.19(gene)|ensembl:ENST00000432992.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0042802""(identical protein binding)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051015""(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036020|interpro:IPR036028|interpro:IPR037957|mint:O60861|rcsb pdb:2LX7|rcsb pdb:2YSH|panther:PTHR23065(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WAPcaqyQaGZcAYHQLKPZgEavtYE177416	rogid:AGTjGZ7Nb4FN05kKzZ7POn5n+xQ9606	intact-crc:563F94DD8A7BBCDA|rigid:Ed0o901rSOkzAEXYFGB6j6VNaUo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIG6	uniprotkb:P51114	intact:EBI-2797019|uniprotkb:A0A0G2RNE6	intact:EBI-713291|uniprotkb:A8K9B8|uniprotkb:Q7Z450|uniprotkb:Q8N6R8|ensembl:ENSP00000350170.3	psi-mi:q5nig6_fratt(display_long)|uniprotkb:FTT_0106c(locus name)	psi-mi:fxr1_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short)|uniprotkb:FMR1 autosomal homolog 1(gene name synonym)|uniprotkb:hFXR1p(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806703|imex:IM-13779-1063	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:1990281""(efflux pump complex)|interpro:IPR006143(Secretion protein HlyD)|refseq:YP_169176.1|interpro:IPR032317|refseq:WP_003019844.1"	"refseq:NP_001013456.1|refseq:NP_001013457.1|refseq:NP_005078.2|ensembl:ENSG00000114416.19(gene)|ensembl:ENST00000357559.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0006915""(apoptotic process)|go:""GO:0007286""(spermatid development)|go:""GO:0007517""(muscle organ development)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0021542""(dentate gyrus development)|go:""GO:0030424""(axon)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0033592""(RNA strand annealing activity)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043005""(neuron projection)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0043034""(costamere)|go:""GO:0043197""(dendritic spine)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045187""(regulation of circadian sleep/wake cycle, sleep)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048170""(positive regulation of long-term neuronal synaptic plasticity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048513""(animal organ development)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0051028""(mRNA transport)|go:""GO:0051292""(nuclear pore complex assembly)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0051966""(regulation of synaptic transmission, glutamatergic)|go:""GO:0060538""(skeletal muscle organ development)|go:""GO:0061157""(mRNA destabilization)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099577""(regulation of translation at presynapse, modulating synaptic transmission)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|go:""GO:1900272""(negative regulation of long-term synaptic potentiation)|go:""GO:1902373""(negative regulation of mRNA catabolic process)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|interpro:IPR047425|interpro:IPR047427|interpro:IPR047494|interpro:IPR047495|interpro:IPR047496|mint:P51114|rcsb pdb:2CPQ|rcsb pdb:3KUF|rcsb pdb:3O8V|reactome:R-HSA-6802952|dip:DIP-40789N|panther:PTHR10603(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:j9DdAUzigby9ZKoJN5AFW0d27v4177416	rogid:pUW5/sakWOiRtZpigPhEMOPJBpk9606	intact-crc:0F77AC6321435B26|rigid:TdDrq0+1XxdlX4trG1jBzdFppt0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06241	uniprotkb:Q5NIA8	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671.3|ensembl:ENSP00000357656.2	intact:EBI-2800376	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:rf1_fratt(display_long)|uniprotkb:FTT_0168(locus name)|uniprotkb:prfA(gene name)|psi-mi:prfA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806696|imex:IM-13779-1060	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|ensembl:ENSG00000010810.18(gene)|ensembl:ENST00000354650.7(transcript)|ensembl:ENST00000368667.6(transcript)|go:""GO:0000304""(response to singlet oxygen)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001764""(neuron migration)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0003015""(heart process)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007216""(G protein-coupled glutamate receptor signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0007612""(learning)|go:""GO:0007631""(feeding behavior)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010467""(gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010730""(negative regulation of hydrogen peroxide biosynthetic process)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030425""(dendrite)|go:""GO:0030900""(forebrain development)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031802""(type 5 metabotropic glutamate receptor binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0038026""(reelin-mediated signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0043204""(perikaryon)|go:""GO:0043274""(phospholipase binding)|go:""GO:0044297""(cell body)|go:""GO:0044325""(transmembrane transporter binding)|interpro:IPR035750|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045471""(response to ethanol)|go:""GO:0046872""(metal ion binding)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050798""(activated T cell proliferation)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050900""(leukocyte migration)|go:""GO:0050966""(detection of mechanical stimulus involved in sensory perception of pain)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070851""(growth factor receptor binding)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097386""(glial cell projection)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1900449""(regulation of glutamate receptor signaling pathway)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902951""(negative regulation of dendritic spine maintenance)|go:""GO:1904645""(response to amyloid-beta)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:1905430""(cellular response to glycine)|go:""GO:1905477""(positive regulation of protein localization to membrane)|go:""GO:1905664""(regulation of calcium ion import across plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|interpro:IPR047924|interpro:IPR050198|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|rcsb pdb:7A2J|rcsb pdb:7A2K|rcsb pdb:7A2L|rcsb pdb:7A2M|rcsb pdb:7A2N|rcsb pdb:7A2O|rcsb pdb:7A2P|rcsb pdb:7A2Q|rcsb pdb:7A2R|rcsb pdb:7A2S|rcsb pdb:7A2T|rcsb pdb:7A2U|rcsb pdb:7A2V|rcsb pdb:7A2W|rcsb pdb:7A2X|rcsb pdb:7A2Y|rcsb pdb:7A2Z|rcsb pdb:7UD6|rcsb pdb:8KDX|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9680350|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9856530|dip:DIP-33876N|panther:PTHR24418(orthology-group)"	"interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004373(Peptide chain release factor 1)|refseq:YP_169234.1|go:""GO:0005737""(cytoplasm)|go:""GO:0016149""(translation release factor activity, codon specific)|refseq:WP_003019960.1|interpro:IPR050057|interpro:IPR045853"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rogid:6lZUlvLNR06AfQiCbfXKwNEmHoE177416	intact-crc:922D2472506D5BC4|rigid:KdHHJE5lCSJ5+i2XVUeLbQHtekQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHR7	uniprotkb:Q96AE4	intact:EBI-2798450|uniprotkb:A0A0G2RMV8	intact:EBI-711404|ensembl:ENSP00000359804.2|uniprotkb:Q12828	psi-mi:q5nhr7_fratt(display_long)|uniprotkb:gdh(gene name)|psi-mi:gdh(display_short)|uniprotkb:FTT_0380c(locus name)	psi-mi:fubp1_human(display_long)|uniprotkb:FUBP1(gene name)|psi-mi:FUBP1(display_short)|uniprotkb:DNA helicase V(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806710|imex:IM-13779-1061	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000166""(nucleotide binding)|go:""GO:0004354""(""glutamate dehydrogenase (NADP+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006537""(glutamate biosynthetic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR014362(Glutamate dehydrogenase)|refseq:YP_169425.1|interpro:IPR033524|refseq:WP_003020063.1|interpro:IPR033922|interpro:IPR036291|interpro:IPR050724|interpro:IPR046346"	"ensembl:ENSG00000162613.18(gene)|ensembl:ENST00000370768.7(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010628""(positive regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|interpro:IPR048249|interpro:IPR048250|interpro:IPR048251|interpro:IPR048252|mint:Q96AE4|rcsb pdb:1J4W|rcsb pdb:2KXH|rcsb pdb:4LIJ|rcsb pdb:6Y24|rcsb pdb:6Y2C|rcsb pdb:6Y2D|rcsb pdb:8P25|refseq:NP_003893.2|refseq:NP_001290362.1|refseq:XP_016858232.1|dip:DIP-47273N|panther:PTHR10288(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hRCfXucQFNjttG1dm0pA5q9GRcI177416	rogid:38IaQgYv8qLMAryXO0lbfzgjjsM9606	intact-crc:1433ED9B39880608|rigid:I1nPlN0z8EpmlxOPhSk+8cjoYcc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEH1	uniprotkb:P23769	intact:EBI-2796391|uniprotkb:A0A0G2RMG3	intact:EBI-2806671|ensembl:ENSP00000345681.2|ensembl:ENSP00000417074.1|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8	psi-mi:q5neh1_fratt(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:FTT_1664(locus name)	psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806678|imex:IM-13779-1059	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_170571.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|refseq:WP_003022611.1|interpro:IPR036897|interpro:IPR036914"	"ensembl:ENSG00000179348.13(gene)|ensembl:ENST00000341105.7(transcript)|ensembl:ENST00000487848.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001655""(urogenital system development)|go:""GO:0001709""(cell fate determination)|go:""GO:0001764""(neuron migration)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0002071""(glandular epithelial cell maturation)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006909""(phagocytosis)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007406""(negative regulation of neuroblast proliferation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010725""(regulation of primitive erythrocyte differentiation)|go:""GO:0021514""(ventral spinal cord interneuron differentiation)|go:""GO:0021533""(cell differentiation in hindbrain)|go:""GO:0021902""(commitment of neuronal cell to specific neuron type in forebrain)|go:""GO:0021954""(central nervous system neuron development)|go:""GO:0033993""(response to lipid)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0035854""(eosinophil fate commitment)|go:""GO:0042472""(inner ear morphogenesis)|go:""GO:0042551""(neuron maturation)|go:""GO:0043306""(positive regulation of mast cell degranulation)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0045165""(cell fate commitment)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0045650""(negative regulation of macrophage differentiation)|go:""GO:0045654""(positive regulation of megakaryocyte differentiation)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0050873""(brown fat cell differentiation)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0060129""(thyroid-stimulating hormone-secreting cell differentiation)|go:""GO:0060216""(definitive hemopoiesis)|go:""GO:0060872""(semicircular canal development)|go:""GO:0061042""(vascular wound healing)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070742""(C2H2 zinc finger domain binding)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090102""(cochlea development)|go:""GO:0097154""(GABAergic neuron differentiation)|go:""GO:1901533""(negative regulation of hematopoietic progenitor cell differentiation)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903444""(negative regulation of brown fat cell differentiation)|go:""GO:1903589""(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000178""(negative regulation of neural precursor cell proliferation)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|go:""GO:2000977""(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|efo:""Orphanet:228423""|ensembl:ENSP00000345681.2|ensembl:ENST00000430265.6|ensembl:ENSP00000400259.2|ensembl:ENSP00000417074.1|panther:PTHR10071(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:YUFWDuTGDB9kX/RHTWI6fMTHxU0177416	rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606	intact-crc:F1C102F943285F7B|rigid:USh2FGAynAwomCloUECat2KZoyE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFW7	uniprotkb:Q9H334	intact:EBI-2800866	intact:EBI-983809|uniprotkb:Q9H332|uniprotkb:Q9H333|uniprotkb:Q9P0R1|intact:EBI-28984754|uniprotkb:A3QVP8|uniprotkb:Q9BSG9|uniprotkb:B3KV70|uniprotkb:G5E9V8|ensembl:ENSP00000318902.5|ensembl:ENSP00000418102.1|ensembl:ENSP00000496990.1|ensembl:ENSP00000497344.1|ensembl:ENSP00000497369.1|ensembl:ENSP00000497454.2|uniprotkb:Q8NAN6	psi-mi:sya_fratt(display_long)|uniprotkb:alaS(gene name)|psi-mi:alaS(display_short)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1096c(locus name)	psi-mi:foxp1_human(display_long)|uniprotkb:FOXP1(gene name)|psi-mi:FOXP1(display_short)|uniprotkb:Mac-1-regulated forkhead(gene name synonym)|uniprotkb:HSPC215(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806736|imex:IM-13779-1067	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_170075.1|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR018162|interpro:IPR018165|interpro:IPR018164|interpro:IPR023033|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004813""(alanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006419""(alanyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:WP_011242268.1|interpro:IPR050058|interpro:IPR045864"	"efo:""Orphanet:391372""|efo:""Orphanet:52417""|efo:""Orphanet:585877""|ensembl:ENSG00000114861.24(gene)|ensembl:ENST00000318789.11(transcript)|ensembl:ENST00000498215.7(transcript)|ensembl:ENST00000648380.1(transcript)|ensembl:ENST00000649528.3(transcript)|ensembl:ENST00000649631.1(transcript)|ensembl:ENST00000650068.2(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0002903""(negative regulation of B cell apoptotic process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006974""(DNA damage response)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0021756""(striatum development)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032651""(regulation of interleukin-1 beta production)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032745""(positive regulation of interleukin-21 production)|go:""GO:0033574""(response to testosterone)|go:""GO:0036035""(osteoclast development)|go:""GO:0042116""(macrophage activation)|go:""GO:0042117""(monocyte activation)|go:""GO:0042118""(endothelial cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045655""(regulation of monocyte differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050861""(positive regulation of B cell receptor signaling pathway)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0061052""(negative regulation of cell growth involved in cardiac muscle cell development)|go:""GO:0061470""(T follicular helper cell differentiation)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:1900424""(regulation of defense response to bacterium)|go:""GO:1901256""(regulation of macrophage colony-stimulating factor production)|go:""GO:1901300""(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:""GO:1901509""(regulation of endothelial tube morphogenesis)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000341""(""regulation of chemokine (C-X-C motif) ligand 2 production"")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|interpro:IPR047412|interpro:IPR050998|mint:Q9H334|rcsb pdb:2KIU|reactome:R-HSA-452723|refseq:NP_001012523.1|refseq:NP_001231737.1|refseq:NP_001231739.1|refseq:NP_001231741.1|refseq:NP_001231743.1|refseq:NP_001231744.1|refseq:NP_001231745.1|refseq:NP_116071.2|refseq:XP_006713165.1|refseq:XP_006713166.1|refseq:XP_006713167.1|refseq:XP_011531886.1|refseq:XP_011531887.1|refseq:XP_016861654.1|refseq:XP_016861655.1|refseq:XP_016861657.1|dip:DIP-36585N|panther:PTHR45796(orthology-group)|ensembl:ENST00000318779.7|ensembl:ENSP00000318721.3|ensembl:ENSP00000318902.5|ensembl:ENST00000484350.5|ensembl:ENSP00000417857.1|ensembl:ENST00000493089.7|ensembl:ENSP00000418524.1|ensembl:ENSP00000418102.1|ensembl:ENSP00000497344.1|ensembl:ENST00000648426.1|ensembl:ENSP00000498110.1|ensembl:ENST00000648710.2|ensembl:ENSP00000497430.2|ensembl:ENST00000648718.1|ensembl:ENSP00000496810.1|ensembl:ENSP00000497369.1|ensembl:ENSP00000496990.1|ensembl:ENSP00000497454.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/19	rogid:jCXq3A5fOs0cyqLU6IhdKsy5Apg177416	rogid:NREo12e1TLPfsul6Ie0l62NqIa89606	intact-crc:BA0BB254C81D047D|rigid:7Xv06lKilDsDeTNm67nDFNExszM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P53539	uniprotkb:Q5NH37	intact:EBI-2806743|uniprotkb:A8K9K5|uniprotkb:A8VJE1|uniprotkb:E9PHJ3|ensembl:ENSP00000245919.3|uniprotkb:A8VJE6|uniprotkb:A8VJF0|uniprotkb:A8VJF3|uniprotkb:A8VJF7|uniprotkb:A8VJG1|uniprotkb:A8VJG5|uniprotkb:A8VJG9|uniprotkb:E7EPR6|uniprotkb:K7EMJ6|uniprotkb:Q49AD7|intact:EBI-11323208|uniprotkb:K7EKC1	intact:EBI-2796219|uniprotkb:A0A0G2RMX6	psi-mi:fosb_human(display_long)|uniprotkb:G0S3(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 3(gene name synonym)|uniprotkb:FOSB(gene name)|psi-mi:FOSB(display_short)|uniprotkb:FosB proto-oncogene, AP-1 transcription factor subunit(gene name synonym)|uniprotkb:Transcription factor AP-1 subunit FosB(gene name synonym)	psi-mi:q5nh37_fratt(display_long)|uniprotkb:hflC(gene name)|psi-mi:hflC(display_short)|uniprotkb:FTT_0634(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806748|imex:IM-13779-1065	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:673556""|efo:""Orphanet:675396""|ensembl:ENSG00000125740.15(gene)|ensembl:ENST00000353609.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007565""(female pregnancy)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0032570""(response to progesterone)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043278""(response to morphine)|go:""GO:0045471""(response to ethanol)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0051412""(response to corticosterone)|go:""GO:0051591""(response to cAMP)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR046347|mint:P53539|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|rcsb pdb:5VPF|rcsb pdb:6UCI|rcsb pdb:6UCL|rcsb pdb:6UCM|rcsb pdb:7UCC|rcsb pdb:7UCD|reactome:R-HSA-9018519|reactome:R-HSA-9031628|refseq:NP_001107643.1|refseq:NP_006723.2|refseq:XP_005258748.1|dip:DIP-60013N|panther:PTHR23351(orthology-group)"	"go:""GO:0016020""(membrane)|interpro:IPR001107(Band 7 protein)|interpro:IPR010200(HflC)|refseq:YP_169655.1|refseq:WP_003018795.1|interpro:IPR036013"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:P8899oVU0RjdVgNIKXWzy/SUmAs9606	rogid:D91nsJMEfSjitv7++sPB1cVKq9M177416	intact-crc:86EB4A9599E340AC|rigid:ZFq3IHrRQ+EjGo05GVPUxSFQKZI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHZ0	uniprotkb:O94915	intact:EBI-2797492|uniprotkb:A0A0G2RNH9	intact:EBI-1104821|uniprotkb:O95640|uniprotkb:Q8WTZ5|uniprotkb:Q9NT40|intact:EBI-1058548|intact:EBI-28979815|ensembl:ENSP00000351113.4	psi-mi:q5nhz0_fratt(display_long)|uniprotkb:lldD1(gene name)|psi-mi:lldD1(display_short)|uniprotkb:FTT_0303c(locus name)	psi-mi:fryl_human(display_long)|uniprotkb:FRYL(gene name)|psi-mi:FRYL(display_short)|uniprotkb:AF4P12(gene name synonym)|uniprotkb:KIAA0826(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 4p12 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806729|imex:IM-13779-1064	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0004460""(""L-lactate dehydrogenase (cytochrome) activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0009060""(aerobic respiration)|go:""GO:0010181""(FMN binding)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR012133(Alpha-hydroxy acid dehydrogenase, FMN-dependent)|interpro:IPR000262(FMN-dependent alpha-hydroxy acid dehydrogenase)|interpro:IPR008259(FMN-dependent alpha-hydroxy acid dehydrogenase, active site)|refseq:YP_169352.1|refseq:WP_003014268.1|interpro:IPR037396"	"refseq:NP_055845.1|ensembl:ENSG00000075539.15(gene)|ensembl:ENST00000358350.9(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0005938""(cell cortex)|go:""GO:0030427""(site of polarized growth)|go:""GO:0031175""(neuron projection development)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025481|interpro:IPR025614|interpro:IPR029473|interpro:IPR039867|interpro:IPR045842|mint:O94915|refseq:XP_016863535.1|panther:PTHR12295(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y9b4dmq9ggvJh1XsJVqfxVBq9OQ177416	rogid:hShMhfhMFUzhUCC/9QfVMnOB7AA9606	intact-crc:95881DBEC2D89AE4|rigid:fD1uPlBQwyhl6se1R25i6KxYxEQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BXM9	uniprotkb:Q5NFK7	intact:EBI-2806720|uniprotkb:Q5T880|uniprotkb:B7Z5S6|uniprotkb:B7Z5W3|uniprotkb:A6NKH7|uniprotkb:Q5T879|uniprotkb:A2A338|ensembl:ENSP00000417492.1	intact:EBI-2797846|uniprotkb:A0A0G2RN70	psi-mi:fsd1l_human(display_long)|uniprotkb:CCDC10(gene name synonym)|uniprotkb:CSDUFD1(gene name synonym)|uniprotkb:FSD1CL(gene name synonym)|uniprotkb:FSD1NL(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 10(gene name synonym)|uniprotkb:FSD1 N-terminal-like protein(gene name synonym)|uniprotkb:FSD1L(gene name)|psi-mi:FSD1L(display_short)	psi-mi:q5nfk7_fratt(display_long)|uniprotkb:rne(gene name)|psi-mi:rne(display_short)|uniprotkb:FTT_1227(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806717|imex:IM-13779-1066	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001274120.1|refseq:NP_001274121.1|refseq:NP_001138785.1|refseq:NP_114125.1|ensembl:ENSG00000106701.13(gene)|ensembl:ENST00000481272.6(transcript)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR035742|interpro:IPR036116|interpro:IPR043136|interpro:IPR050617|refseq:XP_016870672.1|panther:PTHR24099(orthology-group)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006364""(rRNA processing)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008033""(tRNA processing)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008995""(ribonuclease E activity)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019843""(rRNA binding)|interpro:IPR028878|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR019307|interpro:IPR004659(Ribonuclease E and G)|refseq:YP_170185.1|refseq:WP_003021514.1|interpro:IPR048583"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9Mi3GOxa7JjncICrBVBWOl1kCFc9606	rogid:T1YeruV0gQXSr2JVi+sAPAQCsl0177416	intact-crc:95A58194D530797B|rigid:UOYSp1h4oPwiVWgKwryAteUBQzg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6UN15	uniprotkb:Q5NGW4	intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|uniprotkb:B4DIR3|uniprotkb:G3XAD6|intact:EBI-11535474|ensembl:ENSP00000336752.6|ensembl:ENSP00000515339.1	intact:EBI-2798738	psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym)	psi-mi:tdh_fratt(display_long)|uniprotkb:FTT_0713c(locus name)|uniprotkb:tdh(gene name)|psi-mi:tdh(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806766|imex:IM-13779-1068	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:168940""|efo:""Orphanet:314950""|efo:""Orphanet:520""|dip:DIP-42503N|ensembl:ENSG00000145216.17(gene)|ensembl:ENST00000337488.11(transcript)|ensembl:ENST00000703489.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005847""(mRNA cleavage and polyadenylation specificity factor complex)|go:""GO:0006397""(mRNA processing)|interpro:IPR007854(Fip1)|interpro:IPR051187|mint:Q6UN15|rcsb pdb:7K95|rcsb pdb:7ZY4|rcsb pdb:7ZYH|reactome:R-HSA-159231|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|panther:PTHR13484(orthology-group)"	"interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR004627(L-threonine 3-dehydrogenase)|refseq:YP_169728.1|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008743""(L-threonine 3-dehydrogenase activity)|go:""GO:0019518""(L-threonine catabolic process to glycine)|refseq:WP_003020520.1|interpro:IPR036291|interpro:IPR050129"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606	rogid:jmCXDUa63GYPJY+WlAdb21d0wKs177416	intact-crc:9A74DC233FF6E1BD|rigid:yObFfpKmQShZGKcQFtco47hS6wo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGZ3	uniprotkb:P21333	intact:EBI-2806758|uniprotkb:A0A0G2RPQ3	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45|ensembl:ENSP00000358866.3	psi-mi:q5ngz3_fratt(display_long)|uniprotkb:pilD(gene name)|psi-mi:pilD(display_short)|uniprotkb:FTT_0683c(locus name)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806755|imex:IM-13779-1069	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050882|interpro:IPR010627(Peptidase A24A, N-terminal)|interpro:IPR014032(Peptidase A24A, prepilin type IV, bacterial)|interpro:IPR000045(Peptidase A24A, prepilin type IV)|refseq:YP_169699.1|go:""GO:0004190""(aspartic-type endopeptidase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006465""(signal peptide processing)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0032259""(methylation)|refseq:WP_003015759.1"	"efo:""Orphanet:1826""|efo:""Orphanet:2301""|efo:""Orphanet:2484""|efo:""Orphanet:482606""|efo:""Orphanet:555877""|efo:""Orphanet:75497""|efo:""Orphanet:88630""|efo:""Orphanet:90650""|efo:""Orphanet:90652""|efo:""Orphanet:98892""|efo:""Orphanet:99811""|ensembl:ENSG00000196924.19(gene)|ensembl:ENST00000369850.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002102""(podosome)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007195""(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:""GO:0007597""(blood coagulation, intrinsic pathway)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016479""(negative regulation of transcription by RNA polymerase I)|go:""GO:0019900""(kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031523""(Myb complex)|go:""GO:0032233""(positive regulation of actin filament bundle assembly)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043204""(perikaryon)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0044295""(axonal growth cone)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0046332""(SMAD binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050808""(synapse organization)|go:""GO:0050821""(protein stabilization)|go:""GO:0051015""(actin filament binding)|go:""GO:0051020""(GTPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090042""(tubulin deacetylation)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0097368""(establishment of Sertoli cell barrier)|go:""GO:0097440""(apical dendrite)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901381""(positive regulation of potassium ion transmembrane transport)|go:""GO:1902396""(protein localization to bicellular tight junction)|go:""GO:1905000""(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:""GO:1905031""(regulation of membrane repolarization during cardiac muscle cell action potential)|go:""GO:1990779""(glycoprotein Ib-IX-V complex)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|go:""GO:2001224""(positive regulation of neuron migration)|rcsb pdb:6EW1|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|rcsb pdb:7SC4|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|rcsb pdb:7SFT|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|refseq:NP_001104026.1|refseq:NP_001447.2|dip:DIP-1136N|panther:PTHR38537(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:MaxWwDCOvQ5kySPv0FhRmX4SHBo177416	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	intact-crc:A35220E967F34386|rigid:D/l6QBT2usg/qWesaD8Guw3oeXU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q4L180	uniprotkb:Q5NF31	intact:EBI-2806776|uniprotkb:Q6KFX7|uniprotkb:Q6KFX6|uniprotkb:Q8N6Z0|uniprotkb:B2CNV8|uniprotkb:B2CNV7|uniprotkb:Q6KFX5|uniprotkb:Q8IUM3|uniprotkb:Q2YDY5|uniprotkb:Q13597|ensembl:ENSP00000346560.3	intact:EBI-2801218|uniprotkb:A0A0G2RNH8	psi-mi:fil1l_human(display_long)|uniprotkb:COL4A3BPIP(gene name synonym)|uniprotkb:DOC1(gene name synonym)|uniprotkb:GIP90(gene name synonym)|uniprotkb:130 kDa GPBP-interacting protein(gene name synonym)|uniprotkb:90 kDa GPBP-interacting protein(gene name synonym)|uniprotkb:Protein down-regulated in ovarian cancer 1(gene name synonym)|uniprotkb:FILIP1L(gene name)|psi-mi:FILIP1L(display_short)	psi-mi:q5nf31_fratt(display_long)|uniprotkb:nusB(gene name)|psi-mi:nusB(display_short)|uniprotkb:Antitermination factor NusB(gene name synonym)|uniprotkb:FTT_1418c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806773|imex:IM-13779-1070	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269722.1|refseq:NP_001269723.1|refseq:NP_001035924.1|refseq:NP_055705.2|refseq:NP_878913.2|ensembl:ENSG00000168386.19(gene)|ensembl:ENST00000354552.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:1903119""(protein localization to actin cytoskeleton)|interpro:IPR019131|interpro:IPR050719|mint:Q4L180|refseq:XP_006713549.1|panther:PTHR23166(orthology-group)"	"interpro:IPR011605(NusB antitermination factor)|interpro:IPR006027(NusB/RsmB/TIM44)|refseq:YP_170361.1|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|refseq:WP_003022234.1|interpro:IPR035926"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CrddLRTe6kdlMikJ2Js+UBHhf4c9606	rogid:qmu3F+Cf/c260g8lVqz2f62Wpp0177416	intact-crc:51E0535EE99FF8F4|rigid:/HYWzxORGgzZxkaOXvzOdHB6Rzw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHZ4	uniprotkb:Q14192	intact:EBI-2798091	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	psi-mi:syv_fratt(display_long)|uniprotkb:valS(gene name)|psi-mi:valS(display_short)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0299(locus name)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806794|imex:IM-13779-1071	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004832""(valine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006438""(valyl-tRNA aminoacylation)|refseq:YP_169348.1|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR019499|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR033705|refseq:WP_003021639.1|interpro:IPR037118"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:x/UHW8BtUK4O+DP24Ws5NMlvUpw177416	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:797CDAECA48EF912|rigid:wMzYnF8odi1h0V24oC7Ga1NPFRc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH91	uniprotkb:Q14192	intact:EBI-2804245|uniprotkb:A0A0G2RMJ8	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	psi-mi:q5nh91_fratt(display_long)|uniprotkb:sdaA(gene name)|psi-mi:sdaA(display_short)|uniprotkb:FTT_0577(locus name)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806808|imex:IM-13779-1072	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004644(Iron-sulphur-dependent L-serine dehydratase single chain form)|interpro:IPR005130(Serine dehydratase alpha chain)|interpro:IPR005131(Serine dehydratase beta chain)|refseq:YP_169601.1|go:""GO:0003941""(L-serine ammonia-lyase activity)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR029009|refseq:WP_003019268.1|interpro:IPR051318"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:rAJJN6zltZpSciqSe5iWZMw1tLg177416	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:27AFDAECA5B62151|rigid:lsO7CszrfdXHwFxJmxc2ayWKsLE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHC9	uniprotkb:Q9NVK5	intact:EBI-2806815|uniprotkb:A0A0G2RP82	intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395.3	psi-mi:q5nhc9_fratt(display_long)|uniprotkb:nrdA(gene name)|psi-mi:nrdA(display_short)|uniprotkb:FTT_0534c(locus name)	psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806819|imex:IM-13779-1075	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039718|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|refseq:YP_169563.1|go:""GO:0004748""(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:""GO:0005524""(ATP binding)|go:""GO:0005971""(ribonucleoside-diphosphate reductase complex)|go:""GO:0009263""(deoxyribonucleotide biosynthetic process)|refseq:WP_003023237.1"	"refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1|ensembl:ENSG00000111790.14(gene)|ensembl:ENST00000229395.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0009611""(response to wounding)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|panther:PTHR12186(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GRvU6iV8QzZLJWFmOknQ1qpH/wI177416	rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606	intact-crc:11F2206717D7C4A2|rigid:nQApR2uM/sIj2gcvLE8v7EfKSCM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UHY8	uniprotkb:Q5NF67	intact:EBI-396453|uniprotkb:Q76LN0|uniprotkb:Q99690|uniprotkb:Q5EBN3|ensembl:ENSP00000385112.3|intact:EBI-28984869	intact:EBI-2799446|uniprotkb:A0A0G2RPA4	psi-mi:fez2_human(display_long)|uniprotkb:FEZ2(gene name)|psi-mi:FEZ2(display_short)|uniprotkb:Zygin-2(gene name synonym)|uniprotkb:Zygin II(gene name synonym)	psi-mi:q5nf67_fratt(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:FTT_1376(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806826|imex:IM-13779-1073	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001036013.1|refseq:NP_005093.2|ensembl:ENSG00000171055.15(gene)|ensembl:ENST00000405912.8(transcript)|go:""GO:0005737""(cytoplasm)|mint:Q9UHY8|go:""GO:0007165""(signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0007411""(axon guidance)|go:""GO:0030424""(axon)|go:""GO:1902902""(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|panther:PTHR12394(orthology-group)"	"interpro:IPR003231(""Acyl carrier protein (ACP)"")|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR006162(Phosphopantetheine attachment site)|refseq:YP_170325.1|go:""GO:0000035""(acyl binding)|go:""GO:0000036""(acyl carrier activity)|go:""GO:0005829""(cytosol)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0036104""(Kdo2-lipid A biosynthetic process)|interpro:IPR036736|refseq:WP_003025404.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:n5uH+vdgrrvmI+PYkcMUEnAzxwE9606	rogid:zB081U74KR2zeTgcfB7HSoE5ozo177416	intact-crc:9F36E86020593FA0|rigid:2TeYc/73wgepx5cCzle6pEOof6I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14192	uniprotkb:Q5NII1	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	intact:EBI-2797156|uniprotkb:A0A0G2RN00	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:q5nii1_fratt(display_long)|uniprotkb:acnA(gene name)|psi-mi:acnA(display_short)|uniprotkb:FTT_0087(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806801|imex:IM-13779-1074	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR044137|refseq:YP_169161.1|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR018136|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|refseq:WP_003019815.1|interpro:IPR036008"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	rogid:FGVUBUKOHsDquKU0LqPkXCpRg+o177416	intact-crc:0C22ABECA5A4D124|rigid:GHMDhAFRWp1LS1r0IvSlMob1V3U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGE6	uniprotkb:Q86WN1	intact:EBI-2796264|uniprotkb:A0A0G2RNI3	intact:EBI-2623537|uniprotkb:Q6UX75|uniprotkb:Q86Y77|uniprotkb:Q9NXX8|ensembl:ENSP00000399259.2	psi-mi:q5nge6_fratt(display_long)|uniprotkb:prlC(gene name)|psi-mi:prlC(display_short)|uniprotkb:FTT_0899c(locus name)	psi-mi:fcsd1_human(display_long)|uniprotkb:FCHSD1(gene name)|psi-mi:FCHSD1(display_short)|uniprotkb:Protein nervous wreck 2(gene name synonym)|uniprotkb:UNQ737/PRO1431(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806833|imex:IM-13779-1078	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|refseq:YP_169896.1|interpro:IPR024079|refseq:WP_003020904.1|interpro:IPR024077|interpro:IPR045090|interpro:IPR045666|interpro:IPR034005"	"refseq:NP_258260.1|ensembl:ENSG00000197948.11(gene)|ensembl:ENST00000435817.7(transcript)|go:""GO:0007274""(neuromuscular synaptic transmission)|go:""GO:0008289""(lipid binding)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032437""(cuticular plate)|go:""GO:0042995""(cell projection)|interpro:IPR036028|go:""GO:0043204""(perikaryon)|go:""GO:0055037""(recycling endosome)|go:""GO:0061024""(membrane organization)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035460|mint:Q86WN1|panther:PTHR15735(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iZq1PA9Cyrdilxgx1L5ibpr8DmY177416	rogid:sMaYCV8xaZ7qSTKQi2+opZq0ano9606	intact-crc:A752B606A955E1F0|rigid:oluCSfA9aQ/Rp5WRc9uZqiiz0OA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID2	uniprotkb:Q9UKA1	intact:EBI-2796292	intact:EBI-2692340|uniprotkb:Q8NHP3|uniprotkb:Q9UKC8|uniprotkb:Q9P0X5|uniprotkb:Q9P0I0|uniprotkb:B4DIB5|uniprotkb:A8MSK4|uniprotkb:Q9UJT7|uniprotkb:Q4W5A8|uniprotkb:Q9NXN2|ensembl:ENSP00000344866.3	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	psi-mi:fbxl5_human(display_long)|uniprotkb:FBL4(gene name synonym)|uniprotkb:FBL5(gene name synonym)|uniprotkb:FLR1(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 5(gene name synonym)|uniprotkb:F-box protein FBL4/FBL5(gene name synonym)|uniprotkb:p45SKP2-like protein(gene name synonym)|uniprotkb:FBXL5(gene name)|psi-mi:FBXL5(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806872|imex:IM-13779-1077	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"refseq:NP_001180463.1|refseq:NP_001180464.1|refseq:NP_036293.1|ensembl:ENSG00000118564.15(gene)|ensembl:ENST00000341285.8(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019005""(SCF ubiquitin ligase complex)|go:""GO:0031146""(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR012312(Hemerythrin/HHE cation-binding motif)|interpro:IPR032675|interpro:IPR036047|interpro:IPR045808|mint:Q9UKA1|rcsb pdb:3U9J|rcsb pdb:3U9M|rcsb pdb:3V5X|rcsb pdb:3V5Y|rcsb pdb:3V5Z|rcsb pdb:6VCD|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-917937|reactome:R-HSA-983168|panther:PTHR13318(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	rogid:aftM1VKZl11L2zajtM+YVlYZKDw9606	intact-crc:B515E820396DFFA8|rigid:tpbxPpT+vCP7KRC5c4xIGpUSxWg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31994	uniprotkb:Q5NF74	intact:EBI-724784|uniprotkb:O95649|uniprotkb:Q53X85|uniprotkb:Q5VXA9|uniprotkb:Q8NIA1|uniprotkb:A6H8N3|ensembl:ENSP00000351497.5	intact:EBI-2796785|uniprotkb:A0A0G2RND4	psi-mi:fcg2b_human(display_long)|uniprotkb:FCGR2B(gene name)|psi-mi:FCGR2B(display_short)|uniprotkb:CD32(gene name synonym)|uniprotkb:FCG2(gene name synonym)|uniprotkb:IGFR2(gene name synonym)|uniprotkb:Fc-gamma RII-b(gene name synonym)|uniprotkb:CDw32(gene name synonym)	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806865|imex:IM-13779-1079	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|dip:DIP-36638N|ensembl:ENSG00000072694.22(gene)|ensembl:ENST00000358671.10(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0001811""(negative regulation of type I hypersensitivity)|go:""GO:0001814""(negative regulation of antibody-dependent cellular cytotoxicity)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0002252""(immune effector process)|go:""GO:0002266""(follicular dendritic cell activation)|go:""GO:0002313""(mature B cell differentiation involved in immune response)|go:""GO:0002316""(follicular B cell differentiation)|go:""GO:0002436""(immune complex clearance by monocytes and macrophages)|go:""GO:0002605""(negative regulation of dendritic cell antigen processing and presentation)|go:""GO:0002622""(regulation of B cell antigen processing and presentation)|go:""GO:0002638""(negative regulation of immunoglobulin production)|go:""GO:0002819""(regulation of adaptive immune response)|go:""GO:0002865""(negative regulation of acute inflammatory response to antigenic stimulus)|go:""GO:0002922""(positive regulation of humoral immune response)|go:""GO:0002924""(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0005886""(plasma membrane)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006909""(phagocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009617""(response to bacterium)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010469""(regulation of signaling receptor activity)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019770""(IgG receptor activity)|go:""GO:0019772""(low-affinity IgG receptor activity)|go:""GO:0019864""(IgG binding)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0021549""(cerebellum development)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0032693""(negative regulation of interleukin-10 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0043031""(negative regulation of macrophage activation)|go:""GO:0043197""(dendritic spine)|go:""GO:0043318""(negative regulation of cytotoxic T cell degranulation)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045088""(regulation of innate immune response)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0050777""(negative regulation of immune response)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0050869""(negative regulation of B cell activation)|go:""GO:0071219""(cellular response to molecule of bacterial origin)|go:""GO:0090264""(regulation of immune complex clearance by monocytes and macrophages)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1902950""(regulation of dendritic spine maintenance)|go:""GO:1903381""(regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905898""(positive regulation of response to endoplasmic reticulum stress)|go:""GO:2001199""(negative regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050488|mint:P31994|rcsb pdb:2FCB|rcsb pdb:3WJJ|rcsb pdb:5OCC|reactome:R-HSA-198933|refseq:NP_001002273.1|refseq:NP_001002274.1|refseq:NP_001002275.1|refseq:NP_001177757.1|refseq:NP_003992.3|refseq:XP_016856160.1|refseq:XP_016856161.1|panther:PTHR11481(orthology-group)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IfFSt/szCFZQtGRAK7bc1VMwqb09606	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	intact-crc:F0915746E80926AA|rigid:1KJIRgXl5KriW9ha2A+c0md+5Ac	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIQ5	uniprotkb:Q7L513	intact:EBI-2799778|uniprotkb:A0A0G2RQ53	intact:EBI-2806840|uniprotkb:Q5VXA1|uniprotkb:Q5VXA3|uniprotkb:Q5VXA2|uniprotkb:Q9BR57|uniprotkb:Q96PJ2|uniprotkb:Q96PJ0|uniprotkb:Q5VXA4|uniprotkb:Q8NEW4|uniprotkb:Q96PJ1|uniprotkb:Q8WXH3|uniprotkb:Q96PC6|uniprotkb:A0N0M1|uniprotkb:Q5VXB0|uniprotkb:Q96PJ4|ensembl:ENSP00000236938.7|uniprotkb:A6NC03|uniprotkb:A6NL20|uniprotkb:F5H720|uniprotkb:F8W743|uniprotkb:G3V1J2|uniprotkb:Q5VXB1	psi-mi:q5niq5_fratt(display_long)|uniprotkb:FTT_0006(locus name)	psi-mi:fcrla_human(display_long)|uniprotkb:FCRL(gene name synonym)|uniprotkb:FCRL1(gene name synonym)|uniprotkb:FCRLM1(gene name synonym)|uniprotkb:FCRX(gene name synonym)|uniprotkb:FREB(gene name synonym)|uniprotkb:Fc receptor homolog expressed in B-cells(gene name synonym)|uniprotkb:Fc receptor-like and mucin-like protein 1(gene name synonym)|uniprotkb:Fc receptor-like protein(gene name synonym)|uniprotkb:Fc receptor-related protein X(gene name synonym)|uniprotkb:UNQ291/PRO329(orf name)|uniprotkb:FCRLA(gene name)|psi-mi:FCRLA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806858|imex:IM-13779-1076	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|refseq:YP_169087.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015293""(symporter activity)|refseq:WP_003022832.1|interpro:IPR036259|interpro:IPR051084"	"refseq:NP_001171795.1|refseq:NP_001171796.1|refseq:NP_001171799.1|refseq:NP_001171800.1|refseq:NP_001171801.1|refseq:NP_001171802.1|refseq:NP_116127.3|ensembl:ENSG00000132185.18(gene)|ensembl:ENST00000236938.12(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030154""(cell differentiation)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050488|rcsb pdb:4HWN|panther:PTHR11481(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bPCBjXf43BMmeZdBqkqiN5lgd48177416	rogid:8IN4JYjINzn29PadL0irqR3sSeE9606	intact-crc:A0A914D3AEE6778D|rigid:LfQzhQuU0ONby5ozCGoWFyn5Izg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI79	uniprotkb:Q9Y3D0	intact:EBI-2796407|uniprotkb:A0A0G2RQ21	intact:EBI-744045|ensembl:ENSP00000387471.2	psi-mi:q5ni79_fratt(display_long)|uniprotkb:purH(gene name)|psi-mi:purH(display_short)|uniprotkb:FTT_0203c(locus name)	psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806901|imex:IM-13779-1082	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003937""(IMP cyclohydrolase activity)|go:""GO:0004643""(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006189""('de novo' IMP biosynthetic process)|interpro:IPR024051|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR011607(MGS-like)|refseq:YP_169263.1|refseq:WP_003021830.1|interpro:IPR036914"	"refseq:NP_057146.1|ensembl:ENSG00000166595.12(gene)|ensembl:ENST00000422424.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0007059""(chromosome segregation)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0030496""(midbody)|go:""GO:0071817""(MMXD complex)|go:""GO:0097361""(cytosolic [4Fe-4S] assembly targeting complex)|go:""GO:0097428""(obsolete protein maturation by iron-sulfur cluster transfer)|go:""GO:0106035""(obsolete protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830|panther:PTHR12377(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+6gB6EzfOtdLLcQJ/QsAxylPrO8177416	rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606	intact-crc:DC982CFC5615DB41|rigid:QpiSJzwMFQqzPpm2bxGd1NA/XYI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3I1	uniprotkb:Q5NIE3	intact:EBI-1161222|uniprotkb:Q5TGC4|uniprotkb:Q96HM6|uniprotkb:Q9UF21|uniprotkb:Q9UKT2|uniprotkb:B4DNB3|uniprotkb:B4DWX5|uniprotkb:Q5TI86|ensembl:ENSP00000266087.7	intact:EBI-2796495|uniprotkb:A0A0G2RMK7	psi-mi:fbx7_human(display_long)|uniprotkb:FBXO7(gene name)|psi-mi:FBXO7(display_short)|uniprotkb:FBX7(gene name synonym)	psi-mi:q5nie3_fratt(display_long)|uniprotkb:glpA(gene name)|psi-mi:glpA(display_short)|uniprotkb:FTT_0132(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806879|imex:IM-13779-1081	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR15537(orthology-group)|ensembl:ENSG00000100225.18(gene)|ensembl:ENST00000266087.12(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019005""(SCF ubiquitin ligase complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030098""(lymphocyte differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032991""(protein-containing complex)|go:""GO:0040012""(regulation of locomotion)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045620""(negative regulation of lymphocyte differentiation)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097409""(glial cytoplasmic inclusion)|go:""GO:0097414""(classical Lewy body)|go:""GO:0097462""(Lewy neurite)|go:""GO:1901526""(positive regulation of mitophagy)|go:""GO:1903377""(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:""GO:1903599""(positive regulation of autophagy of mitochondrion)|go:""GO:1990037""(Lewy body core)|go:""GO:1990038""(Lewy body corona)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR021625|interpro:IPR029071|interpro:IPR036047|interpro:IPR047118|mint:Q9Y3I1|rcsb pdb:4L9C|rcsb pdb:4L9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001028196.1|refseq:NP_001244919.1|refseq:NP_036311.3|dip:DIP-36125N|efo:""Orphanet:171695"""	"go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0046168""(glycerol-3-phosphate catabolic process)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|refseq:YP_169199.1|interpro:IPR031656|refseq:WP_003019889.1|interpro:IPR038299|interpro:IPR036188"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:i2Mqtw28fJTLURYC+gwr6bcjBoY9606	rogid:GyFomaYDqS6Ilatd7Qqp1Yo0a8M177416	intact-crc:5FBD914FB9C2C112|rigid:GVwv88xl1SYtEigTQAPQWH8RFmA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94887	uniprotkb:Q5NGW4	intact:EBI-2806886|uniprotkb:Q53QM5|uniprotkb:Q9UFE7|uniprotkb:Q8WU27|uniprotkb:B7Z6J8|uniprotkb:F5GZ84|ensembl:ENSP00000264042.3	intact:EBI-2798738	psi-mi:farp2_human(display_long)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:PLEKHC3(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 3(gene name synonym)|uniprotkb:FERM domain-including RhoGEF(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 2(gene name synonym)	psi-mi:tdh_fratt(display_long)|uniprotkb:FTT_0713c(locus name)|uniprotkb:tdh(gene name)|psi-mi:tdh(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806894|imex:IM-13779-1080	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269912.1|refseq:NP_001269913.1|refseq:NP_055623.1|ensembl:ENSG00000006607.14(gene)|ensembl:ENST00000264042.8(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007155""(cell adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0016322""(neuron remodeling)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0022405""(hair cycle process)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0033623""(regulation of integrin activation)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071800""(podosome assembly)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|interpro:IPR051835|mint:O94887|reactome:R-HSA-399955|reactome:R-HSA-9013149|panther:PTHR45858(orthology-group)"	"interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR004627(L-threonine 3-dehydrogenase)|refseq:YP_169728.1|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008743""(L-threonine 3-dehydrogenase activity)|go:""GO:0019518""(L-threonine catabolic process to glycine)|refseq:WP_003020520.1|interpro:IPR036291|interpro:IPR050129"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606	rogid:jmCXDUa63GYPJY+WlAdb21d0wKs177416	intact-crc:45A69E6A436F823B|rigid:5ABNPs1GM7bO/omdLf1W/8QFQOc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFW7	uniprotkb:Q86V20	intact:EBI-2800866	intact:EBI-2560414|ensembl:ENSP00000298784.1|uniprotkb:Q9H991|uniprotkb:O95885	psi-mi:sya_fratt(display_long)|uniprotkb:alaS(gene name)|psi-mi:alaS(display_short)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1096c(locus name)	psi-mi:shld2_human(display_long)|uniprotkb:FAM35A(gene name synonym)|uniprotkb:SHLD2(gene name)|psi-mi:SHLD2(display_short)|uniprotkb:Protein FAM35A(gene name synonym)|uniprotkb:RINN1-REV7-interacting novel NHEJ regulator 2(gene name synonym)|uniprotkb:RINN2(gene name synonym)|uniprotkb:Shield complex subunit 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806945|imex:IM-13779-1084	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_170075.1|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR018162|interpro:IPR018165|interpro:IPR018164|interpro:IPR023033|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004813""(alanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006419""(alanyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:WP_011242268.1|interpro:IPR050058|interpro:IPR045864"	"refseq:NP_061927.2|ensembl:ENSG00000122376.12(gene)|ensembl:ENST00000298784.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0002208""(somatic diversification of immunoglobulins involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0006281""(DNA repair)|go:""GO:0010569""(regulation of double-strand break repair via homologous recombination)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0035861""(site of double-strand break)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR029715|interpro:IPR031589|interpro:IPR049507|interpro:IPR053944|rcsb pdb:6KTO|rcsb pdb:6WWA|rcsb pdb:7L9P|refseq:NP_001317041.1|panther:PTHR14495(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jCXq3A5fOs0cyqLU6IhdKsy5Apg177416	rogid:dEdZvNmGZ1PQM/uvi1f9EiHBFFY9606	intact-crc:F6C56D8B96620C60|rigid:ZMP2sjQYcWktHeV2GofSpdimTJI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96LZ7	uniprotkb:Q5NIF4	intact:EBI-2806908|uniprotkb:Q8N657|uniprotkb:Q8NHM0|uniprotkb:Q8N9A2|uniprotkb:Q4ZG33|uniprotkb:Q6UXN4|uniprotkb:A9UMZ7|uniprotkb:Q8NCV6|uniprotkb:A9UN00|ensembl:ENSP00000346549.3|ensembl:ENSP00000386004.1	intact:EBI-2802846	psi-mi:rmd2_human(display_long)|uniprotkb:RMDN2(gene name)|psi-mi:RMDN2(display_short)|uniprotkb:FAM82A(gene name synonym)|uniprotkb:FAM82A1(gene name synonym)|uniprotkb:Protein FAM82A1(gene name synonym)|uniprotkb:BLOCK18(orf name)|uniprotkb:UNQ9371/PRO34163(orf name)	psi-mi:rf3_fratt(display_long)|uniprotkb:FTT_0118(locus name)|uniprotkb:prfC(gene name)|psi-mi:prfC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806920|imex:IM-13779-1083	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001164262.1|refseq:NP_001164263.1|refseq:NP_001164264.1|refseq:NP_001309140.1|ensembl:ENSG00000115841.21(gene)|ensembl:ENST00000354545.8(transcript)|ensembl:ENST00000406384.5(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005876""(spindle microtubule)|go:""GO:0008017""(microtubule binding)|go:""GO:0016020""(membrane)|go:""GO:0072686""(mitotic spindle)|go:""GO:0097431""(mitotic spindle pole)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR049039|refseq:NP_653314.3|refseq:XP_016858964.1|panther:PTHR16056(orthology-group)"	"interpro:IPR032090|interpro:IPR004548(Peptide chain release factor 3)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:YP_169188.1|interpro:IPR027417|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006449""(regulation of translational termination)|go:""GO:0016149""(translation release factor activity, codon specific)|go:""GO:0016150""(translation release factor activity, codon nonspecific)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR031157|refseq:WP_003019866.1|interpro:IPR038467|interpro:IPR035647|interpro:IPR053905|interpro:IPR041732"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ikcBJ85u2zGJZ/ugq4WwhbwNSm49606	rogid:exUjAaNXwgX443c8S/YiaeKgFoM177416	intact-crc:77C24290B0D1A0B5|rigid:iT6TSW8Ha+Lfwvv9TfZrgYJtwsw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFA4	uniprotkb:Q6ICB0	intact:EBI-2806952|uniprotkb:A0A0G2RM30	intact:EBI-2806959|ensembl:ENSP00000263256.6	psi-mi:q5nfa4_fratt(display_long)|uniprotkb:cydC(gene name)|psi-mi:cydC(display_short)|uniprotkb:FTT_1336(locus name)	psi-mi:desi1_human(display_long)|uniprotkb:DESI1(gene name)|psi-mi:DESI1(display_short)|uniprotkb:FAM152B(gene name synonym)|uniprotkb:PPPDE peptidase domain-containing protein 2(gene name synonym)|uniprotkb:PPPDE2(gene name synonym)|uniprotkb:Polyubiquitinated substrate transporter(gene name synonym)|uniprotkb:Palmitoyl protein thioesterase DESI1(gene name synonym)|uniprotkb:S-depalmitoylase DESI1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806956|imex:IM-13779-1086	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014223(""ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC"")|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|refseq:YP_170288.1|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015421""(ABC-type oligopeptide transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034775""(glutathione transmembrane transport)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_003022089.1|interpro:IPR036640|interpro:IPR039421"	"refseq:NP_056519.1|ensembl:ENSG00000100418.8(gene)|ensembl:ENST00000263256.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0008474""(""palmitoyl-(protein) hydrolase activity"")|go:""GO:0016926""(protein desumoylation)|go:""GO:0016929""(deSUMOylase activity)|go:""GO:0032434""(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0052816""(long-chain fatty acyl-CoA hydrolase activity)|go:""GO:0061676""(importin-alpha family protein binding)|interpro:IPR008580(Protein of unknown function DUF862, eukaryotic)|interpro:IPR042266|rcsb pdb:3EBQ|panther:PTHR12378(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ll8b7075wd9TjalZQ0MpE9pzkGk177416	rogid:KCflYKQJCULKuBzaVNs0SiSpgY09606	intact-crc:5FEFC20A95AD4DED|rigid:tUcMVTeo52p75VlJtorod9VluYw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZS17	uniprotkb:Q5NGF1	intact:EBI-2806927|uniprotkb:Q7Z5R7|uniprotkb:Q4G0A4|uniprotkb:Q96J39|uniprotkb:Q96PV8|uniprotkb:Q9H8D9|uniprotkb:Q8NDA4|uniprotkb:B4DIM2|uniprotkb:B4DEQ9|uniprotkb:E9PBS3|ensembl:ENSP00000368614.3	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	psi-mi:ripr1_human(display_long)|uniprotkb:RIPOR1(gene name)|psi-mi:RIPOR1(display_short)|uniprotkb:FAM65A(gene name synonym)|uniprotkb:KIAA1930(gene name synonym)	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806938|imex:IM-13779-1085	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001180451.1|refseq:NP_001180452.1|refseq:NP_001180453.1|refseq:NP_078795.2|ensembl:ENSG00000039523.20(gene)|ensembl:ENST00000379312.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009611""(response to wounding)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031252""(cell leading edge)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2001107""(negative regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026136|interpro:IPR031780|mint:Q6ZS17|panther:PTHR15829(orthology-group)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6upAD71U4WioIFqcJTDeYXHT35c9606	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	intact-crc:6FB01A7E2BAF9289|rigid:mj30g5eJGlgkAkxe2xnmzAu2cSI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15311	uniprotkb:Q5NEC0	intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934.7|ensembl:ENSP00000356042.3	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806974|imex:IM-13779-1089	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000092820.19(gene)|ensembl:ENST00000337147.11(transcript)|ensembl:ENST00000367075.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0001726""(ruffle)|go:""GO:0001772""(immunological synapse)|go:""GO:0001931""(uropod)|go:""GO:0001951""(intestinal D-glucose absorption)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005903""(brush border)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0008017""(microtubule binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010737""(protein kinase A signaling)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022614""(membrane to membrane docking)|go:""GO:0030033""(microvillus assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030175""(filopodium)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0031528""(microvillus membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0031982""(vesicle)|go:""GO:0032532""(regulation of microvillus length)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|go:""GO:0035088""(establishment or maintenance of apical/basal cell polarity)|go:""GO:0036064""(ciliary basal body)|go:""GO:0040018""(positive regulation of multicellular organism growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0042995""(cell projection)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045177""(apical part of cell)|go:""GO:0045296""(cadherin binding)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051018""(protein kinase A binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051660""(establishment of centrosome localization)|go:""GO:0061028""(establishment of endothelial barrier)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0071944""(cell periphery)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0072697""(protein localization to cell cortex)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098974""(postsynaptic actin cytoskeleton organization)|go:""GO:1902115""(regulation of organelle assembly)|go:""GO:1902896""(terminal web assembly)|go:""GO:1902966""(positive regulation of protein localization to early endosome)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903753""(negative regulation of p38MAPK cascade)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|interpro:IPR046810|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|rcsb pdb:7T1K|rcsb pdb:7T1L|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001104547.1|refseq:NP_003370.2|efo:""Orphanet:88616""|dip:DIP-38868N|panther:PTHR23281(orthology-group)|ensembl:ENSP00000338934.7|ensembl:ENSP00000356042.3"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/17	rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:FDF5373E945D672B|rigid:HDAHRV+Swuq0o0JdEXtuiWv87V0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF53	uniprotkb:Q9H098	intact:EBI-2797592|uniprotkb:A0A0G2RMJ2	intact:EBI-2559748|ensembl:ENSP00000367719.2|ensembl:ENSP00000367723.1|ensembl:ENSP00000367726.3|ensembl:ENSP00000367728.4|ensembl:ENSP00000367731.1|ensembl:ENSP00000417782.1|ensembl:ENSP00000418120.1|ensembl:ENSP00000418330.1|ensembl:ENSP00000419603.1|ensembl:ENSP00000479842.1|uniprotkb:Q6ZSI4|uniprotkb:Q5T9K8|uniprotkb:Q5T9K7|uniprotkb:A8K1P4|uniprotkb:D3DRT2	psi-mi:q5nf53_fratt(display_long)|uniprotkb:recB(gene name)|psi-mi:recB(display_short)|uniprotkb:Exonuclease V subunit RecB(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecB(gene name synonym)|uniprotkb:FTT_1394c(locus name)|uniprotkb:DNA 3'-5' helicase subunit RecB(gene name synonym)	psi-mi:f107b_human(display_long)|uniprotkb:FAM107B(gene name)|psi-mi:FAM107B(display_short)|uniprotkb:C10orf45(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806967|imex:IM-13779-1087	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000287""(magnesium ion binding)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR004586(Exodeoxyribonuclease V, beta subunit)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|refseq:YP_170339.1|interpro:IPR027417|refseq:WP_003022196.1"	refseq:NP_001269624.1|refseq:NP_001269625.1|refseq:NP_001269626.1|refseq:NP_001269627.1|refseq:NP_001269628.1|refseq:NP_001269629.1|refseq:NP_001269630.1|refseq:NP_001269631.1|refseq:NP_001269632.1|ensembl:ENSG00000065809.14(gene)|ensembl:ENST00000378458.6(transcript)|ensembl:ENST00000378462.5(transcript)|ensembl:ENST00000378465.7(transcript)|ensembl:ENST00000378467.8(transcript)|ensembl:ENST00000378470.5(transcript)|ensembl:ENST00000468747.5(transcript)|ensembl:ENST00000478076.5(transcript)|ensembl:ENST00000479731.5(transcript)|ensembl:ENST00000496330.5(transcript)|ensembl:ENST00000622567.4(transcript)|interpro:IPR009533(Protein of unknown function DUF1151)|refseq:XP_011518037.1|refseq:NP_113641.2|refseq:XP_005252673.1|refseq:NP_001307664.1|refseq:NP_001307665.1|refseq:NP_001307666.1|refseq:NP_001307667.1|refseq:NP_001307668.1|refseq:NP_001307669.1|refseq:NP_001307670.1|refseq:XP_016872235.1|refseq:XP_016872236.1|refseq:XP_016872237.1|refseq:XP_016872238.1|panther:PTHR16768(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ii9dJldcaJ9ed2JkD66pMgtmBlQ177416	rogid:5vhE+rQVTlBWd9oSRAgIglJa43w9606	intact-crc:B309FC6763FA82BE|rigid:rJjivk4Ejm798+9NUWVvXwumnRU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH32	uniprotkb:Q9NV70	intact:EBI-2799515	intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514.7|ensembl:ENSP00000370695.2	psi-mi:ilvd_fratt(display_long)|uniprotkb:FTT_0640(locus name)|uniprotkb:ilvD(gene name)|psi-mi:ilvD(display_short)	psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806981|imex:IM-13779-1088	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004404(Dihydroxy-acid dehydratase)|interpro:IPR000581(Dihydroxy-acid and 6-phosphogluconate dehydratase)|interpro:IPR020558|refseq:YP_169660.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004160""(dihydroxy-acid dehydratase activity)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|refseq:WP_003020386.1|interpro:IPR037237|interpro:IPR042096|interpro:IPR050165"	"refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|refseq:XP_005265807.1|refseq:XP_016863898.1|dip:DIP-37579N|ensembl:ENSG00000090989.18(gene)|ensembl:ENST00000346134.11(transcript)|ensembl:ENST00000381295.7(transcript)|go:""GO:0000145""(exocyst)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051607""(defense response to virus)|go:""GO:0090148""(membrane fission)|go:""GO:0090522""(vesicle tethering involved in exocytosis)|go:""GO:0090543""(Flemming body)|interpro:IPR019160|interpro:IPR028258|interpro:IPR048628|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|panther:PTHR16092(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:rp/AkKv3JHJxwOIqAhck+YC5pGc177416	rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606	intact-crc:FDFA6F51DC0FCDB5|rigid:RQxL/HUvW77APQR8euZfm/ZbOLA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHR0	uniprotkb:Q86YB8	intact:EBI-2804868	intact:EBI-2806988|uniprotkb:Q5T1H4|uniprotkb:Q9NR62|uniprotkb:Q8IZ11|ensembl:ENSP00000346635.5|uniprotkb:B4DF57	psi-mi:glmu_fratt(display_long)|uniprotkb:FTT_0387(locus name)|uniprotkb:glmU(gene name)|psi-mi:glmU(display_short)	psi-mi:ero1b_human(display_long)|uniprotkb:ERO1B(gene name)|psi-mi:ERO1B(display_short)|uniprotkb:ERO1LB(gene name synonym)|uniprotkb:Endoplasmic reticulum oxidoreductase beta(gene name synonym)|uniprotkb:Endoplasmic reticulum oxidoreductin-1-like protein B(gene name synonym)|uniprotkb:Oxidoreductin-1-L-beta(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2806995|imex:IM-13779-1090	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005882(UDP-N-acetylglucosamine pyrophosphorylase)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR018357|interpro:IPR011004(Trimeric LpxA-like)|refseq:YP_169432.1|interpro:IPR025877|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003977""(UDP-N-acetylglucosamine diphosphorylase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019134""(glucosamine-1-phosphate N-acetyltransferase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR029044|interpro:IPR038009|interpro:IPR050065|refseq:WP_003027098.1"	"refseq:NP_063944.3|ensembl:ENSG00000086619.15(gene)|ensembl:ENST00000354619.10(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006457""(protein folding)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016972""(thiol oxidase activity)|go:""GO:0030070""(insulin processing)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0071949""(FAD binding)|interpro:IPR007266(Endoplasmic reticulum oxidoreductin 1)|interpro:IPR037192|mint:Q86YB8|reactome:R-HSA-264876|panther:PTHR12613(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:u55iLVubTfB1g8ht4JIk53ncUmQ177416	rogid:1VWEikdUOB9LvVu9PegpX72OYd49606	intact-crc:A1A5FD7E737CED39|rigid:GpoG01JZXc40nyc6q3dY7cmDhS4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIP5	uniprotkb:Q99814	intact:EBI-2797625	intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734.3	psi-mi:gatb_fratt(display_long)|uniprotkb:FTT_0021(locus name)|uniprotkb:gatB(gene name)|psi-mi:gatB(display_short)	psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807020|imex:IM-13779-1092	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0050566""(""asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0070681""(glutaminyl-tRNAGln biosynthesis via transamidation)|interpro:IPR017959|interpro:IPR006075(GatB N-terminal region)|interpro:IPR018027|interpro:IPR003789(GatB/Yqey)|interpro:IPR023168|interpro:IPR004413(""Glutamyl-tRNA(Gln) amidotransferase B subunit"")|interpro:IPR017958|refseq:YP_169097.1|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|refseq:WP_003017411.1"	"ensembl:ENSG00000116016.14(gene)|ensembl:ENST00000263734.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001525""(angiogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0002070""(epithelial cell maturation)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0016607""(nuclear speck)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030324""(lung development)|go:""GO:0042415""(norepinephrine metabolic process)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0043129""(surfactant homeostasis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048625""(myoblast fate commitment)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|rcsb pdb:7Q5V|rcsb pdb:7Q5X|rcsb pdb:7UJV|rcsb pdb:8CK3|rcsb pdb:8CK4|rcsb pdb:8CK8|rcsb pdb:8Q5S|rcsb pdb:8Q64|rcsb pdb:8Q6D|rcsb pdb:8Q6E|reactome:R-HSA-1234158|reactome:R-HSA-1234174|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|refseq:NP_001421.2|efo:""Orphanet:247511""|efo:""Orphanet:276621""|efo:""Orphanet:324299""|dip:DIP-32857N|panther:PTHR23043(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MULE4syC9yNG02pvDj3Le0UVDRw177416	rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606	intact-crc:7C1E669D1AECB086|rigid:EmfgWbm3px2FXU3X2H7Ow6dGIuo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99814	uniprotkb:Q5NEC0	intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734.3	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807013|imex:IM-13779-1093	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000116016.14(gene)|ensembl:ENST00000263734.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001525""(angiogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0002070""(epithelial cell maturation)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0016607""(nuclear speck)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030324""(lung development)|go:""GO:0042415""(norepinephrine metabolic process)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0043129""(surfactant homeostasis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048625""(myoblast fate commitment)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|rcsb pdb:7Q5V|rcsb pdb:7Q5X|rcsb pdb:7UJV|rcsb pdb:8CK3|rcsb pdb:8CK4|rcsb pdb:8CK8|rcsb pdb:8Q5S|rcsb pdb:8Q64|rcsb pdb:8Q6D|rcsb pdb:8Q6E|reactome:R-HSA-1234158|reactome:R-HSA-1234174|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|refseq:NP_001421.2|efo:""Orphanet:247511""|efo:""Orphanet:276621""|efo:""Orphanet:324299""|dip:DIP-32857N|panther:PTHR23043(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:9C032A9D1BC69B78|rigid:zVs62Mapbu6VnGqyJ6U7dNiNfA8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFR1	uniprotkb:Q99814	intact:EBI-2807002|uniprotkb:A0A0G2RPC2	intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734.3	psi-mi:q5nfr1_fratt(display_long)|uniprotkb:aspC2(gene name)|psi-mi:aspC2(display_short)|uniprotkb:FTT_1165c(locus name)	psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807006|imex:IM-13779-1091	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050596|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:YP_170131.1|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:WP_003029497.1"	"ensembl:ENSG00000116016.14(gene)|ensembl:ENST00000263734.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001525""(angiogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0002070""(epithelial cell maturation)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0016607""(nuclear speck)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030324""(lung development)|go:""GO:0042415""(norepinephrine metabolic process)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0043129""(surfactant homeostasis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048625""(myoblast fate commitment)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|rcsb pdb:7Q5V|rcsb pdb:7Q5X|rcsb pdb:7UJV|rcsb pdb:8CK3|rcsb pdb:8CK4|rcsb pdb:8CK8|rcsb pdb:8Q5S|rcsb pdb:8Q64|rcsb pdb:8Q6D|rcsb pdb:8Q6E|reactome:R-HSA-1234158|reactome:R-HSA-1234174|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|refseq:NP_001421.2|efo:""Orphanet:247511""|efo:""Orphanet:276621""|efo:""Orphanet:324299""|dip:DIP-32857N|panther:PTHR23043(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2gd6pdWASGZiPlbvL3U/BI18xec177416	rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606	intact-crc:5605B99D1B9FF7EC|rigid:bExmMrXrkYQCMQdDcrQ2mzTW/t8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06733	uniprotkb:Q5NI74	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590.4|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-2797356|uniprotkb:A0A0G2RNT1	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:q5ni74_fratt(display_long)|uniprotkb:FTT_0209c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807034|imex:IM-13779-1094	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800.16(gene)|ensembl:ENST00000234590.10(transcript)|go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0009615""(response to virus)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016020""(membrane)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031430""(M band)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045933""(positive regulation of muscle contraction)|go:""GO:0051020""(GTPase binding)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903298""(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:""GO:2001171""(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|panther:PTHR11902(orthology-group)"	"go:""GO:0007155""(cell adhesion)|go:""GO:0030001""(metal ion transport)|go:""GO:0046872""(metal ion binding)|interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006129(Adhesin B)|refseq:YP_169268.1|refseq:WP_003017523.1|interpro:IPR050492"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:SNzKG6SXy0yUlUpZyU9sv3eNyRk177416	intact-crc:F27517924948B6C8|rigid:kFdHPV7gdOHGk4DX29ZIpxxbRu0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEP5	uniprotkb:Q9Y6C2	intact:EBI-2802256|uniprotkb:A0A0G2RP86	intact:EBI-744586|intact:EBI-902920|uniprotkb:A5PL03|uniprotkb:H0Y7A0|uniprotkb:Q53SY9|uniprotkb:Q96G58|uniprotkb:Q96IH6|uniprotkb:Q9UG76|uniprotkb:A0A0C4DFX3|ensembl:ENSP00000369677.4	psi-mi:q5nep5_fratt(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:FTT_1575c(locus name)	psi-mi:emil1_human(display_long)|uniprotkb:EMILIN1(gene name)|psi-mi:EMILIN1(display_short)|uniprotkb:EMI(gene name synonym)|uniprotkb:Elastin microfibril interface-located protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807048|imex:IM-13779-1095	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:YP_170497.1|refseq:WP_003022482.1|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006265""(DNA topological change)|go:""GO:0009330""(""DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex"")|go:""GO:0034335""(DNA negative supercoiling activity)|interpro:IPR035516|interpro:IPR050220|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)"	"efo:""Orphanet:485418""|dip:DIP-35733N|ensembl:ENSG00000138080.14(gene)|ensembl:ENST00000380320.9(transcript)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016477""(cell migration)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030023""(extracellular matrix constituent conferring elasticity)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032966""(negative regulation of collagen biosynthetic process)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050866""(negative regulation of cell activation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060392""(negative regulation of SMAD protein signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:1900426""(positive regulation of defense response to bacterium)|go:""GO:1900747""(negative regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1901731""(positive regulation of platelet aggregation)|go:""GO:1904027""(negative regulation of collagen fibril organization)|go:""GO:1905522""(negative regulation of macrophage migration)|go:""GO:1990971""(EMILIN complex)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR011489(EMI)|interpro:IPR050392|mint:Q9Y6C2|rcsb pdb:2KA3|rcsb pdb:2OII|reactome:R-HSA-2129379|refseq:NP_008977.1|panther:PTHR15427(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:44gSSjy20htbaT6NxBBvXLNb2sw177416	rogid:lJnDOaq3HA5TUGd1Skz/1s3DIxM9606	intact-crc:76BFC16DBDE3AB2D|rigid:pzFs4lTdgARBtbDiqrkO8BOODXk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF50	uniprotkb:P14625	intact:EBI-2799423|uniprotkb:A0A0G2RN72	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767.4	psi-mi:q5nf50_fratt(display_long)|uniprotkb:Exonuclease V subunit RecC(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecC(gene name synonym)|uniprotkb:recC(gene name)|psi-mi:recC(display_short)|uniprotkb:FTT_1397c(locus name)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)|uniprotkb:HSPC4(gene name synonym)|uniprotkb:Heat shock protein family C member 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807027|imex:IM-13779-1096	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006697(Exodeoxyribonuclease V, RecC subunit)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|refseq:YP_170342.1|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|refseq:WP_003022201.1|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR041500"	"panther:PTHR11528(orthology-group)|refseq:NP_003290.1|ensembl:ENSG00000166598.16(gene)|ensembl:ENST00000299767.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030496""(midbody)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|reactome:R-HSA-8957275|go:""GO:0031247""(actin rod assembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033018""(sarcoplasmic reticulum lumen)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042470""(melanosome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051208""(sequestering of calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071287""(cellular response to manganese ion)|go:""GO:0071318""(cellular response to ATP)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|rcsb pdb:7ULL|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|dip:DIP-36060N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:dix8s5jOlPbCloD4EjJhnk5rYr4177416	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	intact-crc:53EA9402D52A2EAC|rigid:7mqMC0YhJTki21+9S3S214octmo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8G8T7	uniprotkb:Q9Y6C2	intact:EBI-2796603	intact:EBI-744586|intact:EBI-902920|uniprotkb:A5PL03|uniprotkb:H0Y7A0|uniprotkb:Q53SY9|uniprotkb:Q96G58|uniprotkb:Q96IH6|uniprotkb:Q9UG76|uniprotkb:A0A0C4DFX3|ensembl:ENSP00000369677.4	psi-mi:q8g8t7_fratl(display_long)|uniprotkb:asd(gene name)|psi-mi:asd(display_short)	psi-mi:emil1_human(display_long)|uniprotkb:EMILIN1(gene name)|psi-mi:EMILIN1(display_short)|uniprotkb:EMI(gene name synonym)|uniprotkb:Elastin microfibril interface-located protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807041|imex:IM-13779-1097	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004073""(aspartate-semialdehyde dehydrogenase activity)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0009088""(threonine biosynthetic process)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0019877""(diaminopimelate biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|refseq:WP_003020169.1|interpro:IPR000319(Aspartate-semialdehyde dehydrogenase, conserved site)|interpro:IPR011534(Aspartate-semialdehyde dehydrogenase, proteobacteria)|interpro:IPR000534(Semialdehyde dehydrogenase, NAD-binding)|interpro:IPR012280(Semialdehyde dehydrogenase, dimerisation region)|rcsb pdb:4WOJ|interpro:IPR036291"	"efo:""Orphanet:485418""|dip:DIP-35733N|ensembl:ENSG00000138080.14(gene)|ensembl:ENST00000380320.9(transcript)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016477""(cell migration)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030023""(extracellular matrix constituent conferring elasticity)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032966""(negative regulation of collagen biosynthetic process)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050866""(negative regulation of cell activation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060392""(negative regulation of SMAD protein signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:1900426""(positive regulation of defense response to bacterium)|go:""GO:1900747""(negative regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1901731""(positive regulation of platelet aggregation)|go:""GO:1904027""(negative regulation of collagen fibril organization)|go:""GO:1905522""(negative regulation of macrophage migration)|go:""GO:1990971""(EMILIN complex)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR011489(EMI)|interpro:IPR050392|mint:Q9Y6C2|rcsb pdb:2KA3|rcsb pdb:2OII|reactome:R-HSA-2129379|refseq:NP_008977.1|panther:PTHR15427(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HbI1K+KPeND7CwD3y7jf62tQ4ZA119856	rogid:lJnDOaq3HA5TUGd1Skz/1s3DIxM9606	intact-crc:268C8FD7805B3718|rigid:M37Tpv4HWNcP39DmAlBkPBa6c7M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:O75821	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108.3	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807069|imex:IM-13779-1101	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"refseq:NP_003746.2|ensembl:ENSG00000130811.12(gene)|ensembl:ENST00000253108.9(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0075525""(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31115N|panther:PTHR10352(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606	intact-crc:6A91985566E46FEC|rigid:HtgSyitbeLrAaiKOq+Y5DcXHq44	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H9B1	uniprotkb:Q5NFY4	intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980.1	intact:EBI-2799645|uniprotkb:A0A0G2RQ80	psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym)	psi-mi:q5nfy4_fratt(display_long)|uniprotkb:FTT_1079c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807076|imex:IM-13779-1099	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000181090.21(gene)|ensembl:ENST00000460843.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0002039""(p53 binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0006346""(DNA methylation-dependent constitutive heterochromatin formation)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0016604""(nuclear body)|go:""GO:0018026""(peptidyl-lysine monomethylation)|go:""GO:0018027""(peptidyl-lysine dimethylation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046974""(histone H3K9 methyltransferase activity)|go:""GO:0046976""(histone H3K27 methyltransferase activity)|go:""GO:0060992""(response to fungicide)|go:""GO:0070742""(C2H2 zinc finger domain binding)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140718""(facultative heterochromatin formation)|go:""GO:0140947""(histone H3K9me2 methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|interpro:IPR046341|interpro:IPR047762|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|rcsb pdb:7T7M|rcsb pdb:8XPT|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750|reactome:R-HSA-9843970|refseq:NP_001138999.1|refseq:NP_079033.4|dip:DIP-34585N|efo:""Orphanet:261652""|efo:""Orphanet:96147""|panther:PTHR46307(orthology-group)"	refseq:YP_170058.1|refseq:WP_003026641.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606	rogid:v1mSgBDe90RxW8uHIi9a67zCxJs177416	intact-crc:B5C0DE84CD451365|rigid:7/DVR99tyu67uSNlw7FOEMBbg80	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q32P44	uniprotkb:Q5NIL8	intact:EBI-1046713|ensembl:ENSP00000378254.2|uniprotkb:Q6ZQW7|uniprotkb:Q8NA55|intact:EBI-2556256	intact:EBI-2797707|uniprotkb:A0A0G2RN29	psi-mi:emal3_human(display_long)|uniprotkb:EML3(gene name)|psi-mi:EML3(display_short)	psi-mi:q5nil8_fratt(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:FTT_0049(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807055|imex:IM-13779-1100	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"intact:EBI-1058671(primary-reference)|ensembl:ENSG00000149499.12(gene)|ensembl:ENST00000394773.7(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005876""(spindle microtubule)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030496""(midbody)|go:""GO:0051301""(cell division)|go:""GO:1901673""(regulation of mitotic spindle assembly)|go:""GO:1990498""(mitotic spindle microtubule)|interpro:IPR001680(WD40 repeat)|interpro:IPR005108(HELP)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR050630|mint:Q32P44|refseq:NP_694997.2|refseq:NP_001287722.1|panther:PTHR13720(orthology-group)"	"go:""GO:0000166""(nucleotide binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|refseq:YP_169124.1|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010214(Transcription termination factor NusA, C-terminal duplication)|interpro:IPR010213(Transcription termination factor NusA)|interpro:IPR025249|interpro:IPR030842|refseq:WP_003019733.1|interpro:IPR036555"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Q5NalpeOEiROb0QG6vDt/b0Sna49606	rogid:h3B/JHGk+VSXL6iylODRYTPeDAc177416	intact-crc:C1EB1B65B9E531A9|rigid:Q+uwIOx/liOGa9YmgJFbeh1t2HQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P32519	uniprotkb:Q5NEC0	intact:EBI-765526|uniprotkb:Q9UDE1|uniprotkb:Q8N6F6|ensembl:ENSP00000239882.3|uniprotkb:B4E2I5|uniprotkb:E9PDQ9	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:elf1_human(display_long)|uniprotkb:E74-like factor 1(gene name synonym)|uniprotkb:ELF1(gene name)|psi-mi:ELF1(display_short)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807062|imex:IM-13779-1098	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_758961.1|ensembl:ENSG00000120690.17(gene)|ensembl:ENST00000239882.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR022084|interpro:IPR036388|interpro:IPR036390|interpro:IPR046328|mint:P32519|rcsb pdb:8BZM|reactome:R-HSA-8939245|reactome:R-HSA-8939247|refseq:NP_001138825.1|refseq:XP_005266333.1|refseq:XP_005266334.1|refseq:XP_011533252.1|refseq:XP_016875898.1|refseq:XP_016875899.1|refseq:XP_016875900.1|refseq:XP_016875901.1|refseq:XP_016875902.1|dip:DIP-185N|panther:PTHR11849(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bkNv2VvMBvrmLtvw8qhFrj9Zgqg9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:D6AE1CB903F4A08E|rigid:CW7fFTs8YkBvn9g6yOp21XNf0lE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEB4	uniprotkb:P00533	intact:EBI-2797653|uniprotkb:A0A0G2RPR1	intact:EBI-297353|uniprotkb:Q9BZS2|uniprotkb:Q9GZX1|uniprotkb:Q9H2C9|uniprotkb:Q9H3C9|uniprotkb:Q9UMD7|uniprotkb:Q9UMD8|uniprotkb:Q9UMG5|uniprotkb:O00688|uniprotkb:O00732|uniprotkb:P06268|uniprotkb:Q14225|uniprotkb:Q92795|intact:EBI-28985169|uniprotkb:Q68GS5|ensembl:ENSP00000275493.2	psi-mi:q5neb4_fratt(display_long)|uniprotkb:yegQ(gene name)|psi-mi:yegQ(display_short)|uniprotkb:FTT_1726(locus name)	psi-mi:egfr_human(display_long)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:ERBB(gene name synonym)|uniprotkb:HER1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807083|imex:IM-13779-1103	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001539(Peptidase U32)|refseq:YP_170628.1|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|interpro:IPR032525|refseq:WP_003022701.1|interpro:IPR051454"	"ensembl:ENSG00000146648.21(gene)|ensembl:ENST00000275493.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001503""(ossification)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001942""(hair follicle development)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007435""(salivary gland morphogenesis)|go:""GO:0007494""(midgut development)|go:""GO:0007611""(learning or memory)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016101""(diterpenoid metabolic process)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0022008""(neurogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0033594""(response to hydroxyisoflavone)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038134""(ERBB2-EGFR signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042311""(vasodilation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042698""(ovulation cycle)|go:""GO:0042743""(hydrogen peroxide metabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0043586""(tongue development)|go:""GO:0045121""(membrane raft)|go:""GO:0045296""(cadherin binding)|go:""GO:0045737""(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048143""(astrocyte activation)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048408""(epidermal growth factor binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048546""(digestive tract morphogenesis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051015""(actin filament binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051205""(protein insertion into membrane)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051968""(positive regulation of synaptic transmission, glutamatergic)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060571""(morphogenesis of an epithelial fold)|go:""GO:0061029""(eyelid development in camera-type eye)|go:""GO:0070141""(response to UV-A)|go:""GO:0070257""(positive regulation of mucus secretion)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070435""(Shc-EGFR complex)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097421""(liver regeneration)|go:""GO:0097489""(multivesicular body, internal vesicle lumen)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900020""(positive regulation of protein kinase C activity)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|go:""GO:1902722""(positive regulation of prolactin secretion)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905208""(negative regulation of cardiocyte differentiation)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|interpro:IPR049328|interpro:IPR050122|mint:P00533|rcsb pdb:1IVO|rcsb pdb:1M14|rcsb pdb:1M17|rcsb pdb:1MOX|rcsb pdb:1NQL|rcsb pdb:1XKK|rcsb pdb:1YY9|rcsb pdb:1Z9I|rcsb pdb:2EB2|rcsb pdb:2EB3|rcsb pdb:2GS2|rcsb pdb:2GS6|rcsb pdb:2GS7|rcsb pdb:2ITN|rcsb pdb:2ITO|rcsb pdb:2ITP|rcsb pdb:2ITQ|rcsb pdb:2ITT|rcsb pdb:2ITU|rcsb pdb:2ITV|rcsb pdb:2ITW|rcsb pdb:2ITX|rcsb pdb:2ITY|rcsb pdb:2ITZ|rcsb pdb:2KS1|rcsb pdb:2J5E|rcsb pdb:2J5F|rcsb pdb:2J6M|rcsb pdb:2JIT|rcsb pdb:2JIU|rcsb pdb:2JIV|rcsb pdb:2M0B|rcsb pdb:2M20|rcsb pdb:2N5S|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:2RGP|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BEL|rcsb pdb:3BUO|rcsb pdb:3C09|rcsb pdb:3G5V|rcsb pdb:3G5Y|rcsb pdb:3GOP|rcsb pdb:3GT8|rcsb pdb:3IKA|rcsb pdb:3LZB|rcsb pdb:3NJP|rcsb pdb:3OB2|rcsb pdb:3OP0|rcsb pdb:3P0Y|rcsb pdb:3PFV|rcsb pdb:3POZ|rcsb pdb:3QWQ|rcsb pdb:3UG1|rcsb pdb:3UG2|rcsb pdb:3VJN|rcsb pdb:3VJO|rcsb pdb:3VRP|rcsb pdb:3VRR|rcsb pdb:3W2O|rcsb pdb:3W2P|rcsb pdb:3W2Q|rcsb pdb:3W2R|rcsb pdb:3W2S|rcsb pdb:3W32|rcsb pdb:3W33|rcsb pdb:4G5J|rcsb pdb:4G5P|rcsb pdb:4HJO|rcsb pdb:4I1Z|rcsb pdb:4I20|rcsb pdb:4I21|rcsb pdb:4I22|rcsb pdb:4I23|rcsb pdb:4I24|rcsb pdb:4JQ7|rcsb pdb:4JQ8|rcsb pdb:4JR3|rcsb pdb:4JRV|rcsb pdb:4KRL|rcsb pdb:4KRM|rcsb pdb:4KRO|rcsb pdb:4KRP|rcsb pdb:4LI5|rcsb pdb:4LL0|rcsb pdb:4LQM|rcsb pdb:4LRM|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4R5S|rcsb pdb:4RIW|rcsb pdb:4RIX|rcsb pdb:4RIY|rcsb pdb:4RJ4|rcsb pdb:4RJ5|rcsb pdb:4RJ6|rcsb pdb:4RJ7|rcsb pdb:4RJ8|rcsb pdb:4TKS|rcsb pdb:4UIP|rcsb pdb:4UV7|rcsb pdb:4WD5|rcsb pdb:4WKQ|rcsb pdb:4WRG|rcsb pdb:4ZAU|rcsb pdb:4ZJV|rcsb pdb:4ZSE|rcsb pdb:5C8K|rcsb pdb:5C8M|rcsb pdb:5C8N|rcsb pdb:5CAL|rcsb pdb:5CAN|rcsb pdb:5CAO|rcsb pdb:5CAP|rcsb pdb:5CAQ|rcsb pdb:5CAS|rcsb pdb:5CAU|rcsb pdb:5CAV|rcsb pdb:5CNN|rcsb pdb:5CNO|rcsb pdb:5CZH|rcsb pdb:5CZI|rcsb pdb:5D41|rcsb pdb:5EDP|rcsb pdb:5EDQ|rcsb pdb:5EDR|rcsb pdb:5EM5|rcsb pdb:5EM6|rcsb pdb:5EM7|rcsb pdb:5EM8|rcsb pdb:5FED|rcsb pdb:5FEE|rcsb pdb:5FEQ|rcsb pdb:5GMP|rcsb pdb:5GNK|rcsb pdb:5GTY|rcsb pdb:5GTZ|rcsb pdb:5HCX|rcsb pdb:5HCY|rcsb pdb:5HCZ|rcsb pdb:5HG5|rcsb pdb:5HG7|rcsb pdb:5HG8|rcsb pdb:5HG9|rcsb pdb:5HIB|rcsb pdb:5HIC|rcsb pdb:5J9Y|rcsb pdb:5J9Z|rcsb pdb:5JEB|rcsb pdb:5LV6|rcsb pdb:5SX4|rcsb pdb:5SX5|rcsb pdb:5U8L|rcsb pdb:5UG8|rcsb pdb:5UG9|rcsb pdb:5UGA|rcsb pdb:5UGB|rcsb pdb:5UGC|rcsb pdb:5UWD|rcsb pdb:5WB7|rcsb pdb:5WB8|rcsb pdb:5X26|rcsb pdb:5X27|rcsb pdb:5X28|rcsb pdb:5X2A|rcsb pdb:5X2C|rcsb pdb:5X2F|rcsb pdb:5X2K|rcsb pdb:5XDK|rcsb pdb:5XDL|rcsb pdb:5XGM|rcsb pdb:5XGN|rcsb pdb:5XWD|rcsb pdb:5Y25|rcsb pdb:5Y9T|rcsb pdb:5YU9|rcsb pdb:5ZTO|rcsb pdb:5ZWJ|rcsb pdb:6ARU|rcsb pdb:6B3S|rcsb pdb:6D8E|rcsb pdb:6DUK|rcsb pdb:6JRJ|rcsb pdb:6JRK|rcsb pdb:6JRX|rcsb pdb:6JWL|rcsb pdb:6JX0|rcsb pdb:6JX4|rcsb pdb:6JXT|rcsb pdb:6JZ0|rcsb pdb:6LUB|rcsb pdb:6LUD|rcsb pdb:6P1D|rcsb pdb:6P1L|rcsb pdb:6P8Q|rcsb pdb:6S89|rcsb pdb:6S8A|rcsb pdb:6S9B|rcsb pdb:6S9C|rcsb pdb:6S9D|rcsb pdb:6TFU|rcsb pdb:6TFV|rcsb pdb:6TFW|rcsb pdb:6TFY|rcsb pdb:6TFZ|rcsb pdb:6TG0|rcsb pdb:6TG1|rcsb pdb:6V5N|rcsb pdb:6V5P|rcsb pdb:6V66|rcsb pdb:6V6K|rcsb pdb:6V6O|rcsb pdb:6VH4|rcsb pdb:6VHN|rcsb pdb:6VHP|rcsb pdb:6WA2|rcsb pdb:6WAK|rcsb pdb:6WXN|rcsb pdb:6XL4|rcsb pdb:6Z4B|rcsb pdb:6Z4D|rcsb pdb:7A2A|rcsb pdb:7A6I|rcsb pdb:7A6J|rcsb pdb:7A6K|rcsb pdb:7AEI|rcsb pdb:7AEM|rcsb pdb:7B85|rcsb pdb:7ER2|rcsb pdb:7JXI|rcsb pdb:7JXK|rcsb pdb:7JXL|rcsb pdb:7JXM|rcsb pdb:7JXP|rcsb pdb:7JXQ|rcsb pdb:7JXW|rcsb pdb:7K1H|rcsb pdb:7K1I|rcsb pdb:7KXZ|rcsb pdb:7KY0|rcsb pdb:7LEN|rcsb pdb:7LFR|rcsb pdb:7LFS|rcsb pdb:7LG8|rcsb pdb:7LGS|rcsb pdb:7LTX|rcsb pdb:7OM4|rcsb pdb:7OXB|rcsb pdb:7SI1|rcsb pdb:7SYD|rcsb pdb:7SYE|rcsb pdb:7SZ0|rcsb pdb:7SZ1|rcsb pdb:8A2B|rcsb pdb:7SZ5|rcsb pdb:7SZ7|rcsb pdb:7T4I|rcsb pdb:7T4J|rcsb pdb:7TVD|rcsb pdb:7U98|rcsb pdb:7U99|rcsb pdb:7U9A|rcsb pdb:7UKV|rcsb pdb:7UKW|rcsb pdb:7VRA|rcsb pdb:7VRE|rcsb pdb:7ZYM|rcsb pdb:7ZYN|rcsb pdb:7ZYP|rcsb pdb:7ZYQ|rcsb pdb:8A27|rcsb pdb:8A2A|rcsb pdb:8A2D|rcsb pdb:8D73|rcsb pdb:8D76|rcsb pdb:8DSW|rcsb pdb:8EME|rcsb pdb:8F1H|rcsb pdb:8F1W|rcsb pdb:8F1X|rcsb pdb:8F1Y|rcsb pdb:8F1Z|rcsb pdb:8FV3|rcsb pdb:8FV4|rcsb pdb:8G63|rcsb pdb:8GB4|rcsb pdb:8GK5|rcsb pdb:8H7X|rcsb pdb:8HGO|rcsb pdb:8HGP|rcsb pdb:8HGS|rcsb pdb:8HV1|rcsb pdb:8HV2|rcsb pdb:8HV3|rcsb pdb:8HV4|rcsb pdb:8HV5|rcsb pdb:8HV6|rcsb pdb:8HV7|rcsb pdb:8HV8|rcsb pdb:8HV9|rcsb pdb:8HVA|rcsb pdb:8HY7|rcsb pdb:8KFQ|rcsb pdb:8PNZ|rcsb pdb:8PO0|rcsb pdb:8PO1|rcsb pdb:8PO2|rcsb pdb:8PO3|rcsb pdb:8PO4|rcsb pdb:8S1M|rcsb pdb:8SC7|rcsb pdb:8TJL|rcsb pdb:8TO3|rcsb pdb:8TO4|rcsb pdb:8UKV|rcsb pdb:8UKW|rcsb pdb:8UKX|rcsb pdb:8WD4|rcsb pdb:9EWT|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-212718|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-445144|reactome:R-HSA-5637810|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8857538|reactome:R-HSA-8863795|reactome:R-HSA-8866910|reactome:R-HSA-9009391|reactome:R-HSA-9013507|reactome:R-HSA-9609690|reactome:R-HSA-9634638|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9820960|refseq:NP_005219.2|refseq:NP_958439.1|refseq:NP_958440.1|refseq:NP_958441.1|dip:DIP-405N|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:294023""|ensembl:ENSP00000275493.2|ensembl:ENST00000342916.7|ensembl:ENSP00000342376.3|ensembl:ENST00000344576.7|ensembl:ENSP00000345973.2|ensembl:ENST00000420316.6|ensembl:ENSP00000413843.2|panther:PTHR24416(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:V8v+igazfnHs0EcKm43UGRWNmrY177416	rogid:gXB5slVTC+z8DdqqXIzXG7lDwk09606	intact-crc:63D7A2BC6336DD7E|rigid:nK5o2iKB0JbOvUITqmekxA8lPyU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF37	uniprotkb:Q9UHF1	intact:EBI-2798724	intact:EBI-949532|uniprotkb:Q5M7Y5|uniprotkb:Q5VUD5|uniprotkb:Q96EG0|uniprotkb:B3KRP0|uniprotkb:M9VTX9|ensembl:ENSP00000307843.7|ensembl:ENSP00000360763.3|ensembl:ENSP00000360764.1|ensembl:ENSP00000385639.3	psi-mi:syp_fratt(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1412(locus name)	psi-mi:egfl7_human(display_long)|uniprotkb:Multiple epidermal growth factor-like domains protein 7(gene name synonym)|uniprotkb:Zneu1(gene name synonym)|uniprotkb:Vascular endothelial statin(gene name synonym)|uniprotkb:NOTCH4-like protein(gene name synonym)|uniprotkb:EGFL7(gene name)|psi-mi:EGFL7(display_short)|uniprotkb:MEGF7(gene name synonym)|uniprotkb:UNQ187/PRO1449(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807090|imex:IM-13779-1102	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044140|refseq:YP_170355.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|interpro:IPR033730|refseq:WP_003022224.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR045864|interpro:IPR050062"	"refseq:NP_057299.1|refseq:NP_958854.1|refseq:XP_011517066.1|refseq:XP_011517067.1|refseq:XP_011517068.1|ensembl:ENSG00000172889.16(gene)|ensembl:ENST00000308874.12(transcript)|ensembl:ENST00000371698.3(transcript)|ensembl:ENST00000371699.5(transcript)|ensembl:ENST00000406555.7(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001568""(blood vessel development)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0009986""(cell surface)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011489(EMI)|interpro:IPR013111(EGF, extracellular)|interpro:IPR018097|interpro:IPR050969|mint:Q9UHF1|panther:PTHR14949(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6/QkU5JRWJEBZMwaR9J83no0ffk177416	rogid:HzaJXQm4JE8bXXE+/ugmqGjpjZA9606	intact-crc:4BECEAA3BD3FE207|rigid:xgGiBevuJOpZSQsKRHHRfPeiyR4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFM0	uniprotkb:P13639	intact:EBI-2800168|uniprotkb:A0A0G2RNN7	intact:EBI-352560|uniprotkb:A0A384N6H1|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940.5	psi-mi:q5nfm0_fratt(display_long)|uniprotkb:FTT_1214c(locus name)	psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807097|imex:IM-13779-1104	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR000150(Cof protein)|refseq:YP_170172.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0016791""(phosphatase activity)|refseq:WP_003021483.1|interpro:IPR036412"	"ensembl:ENSG00000167658.16(gene)|ensembl:ENST00000309311.7(transcript)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0016235""(aggresome)|go:""GO:0019901""(protein kinase binding)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043022""(ribosome binding)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:8XSX|rcsb pdb:8Y0W|rcsb pdb:8Y0X|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725|refseq:NP_001952.1|efo:""Orphanet:101112""|panther:PTHR42908(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sGXWuuIontV2yTFO4nOU2nzzlbI177416	rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606	intact-crc:C4558591FAEA1782|rigid:5cxvPDqJtDr2Z6mBhFKKfNcr1L8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13639	uniprotkb:Q5NFE2	intact:EBI-352560|uniprotkb:A0A384N6H1|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940.5	intact:EBI-2807104|uniprotkb:A0A0G2RMT3	psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym)	psi-mi:q5nfe2_fratt(display_long)|uniprotkb:glk1(gene name)|psi-mi:glk1(display_short)|uniprotkb:FTT_1295c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807108|imex:IM-13779-1105	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000167658.16(gene)|ensembl:ENST00000309311.7(transcript)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0016235""(aggresome)|go:""GO:0019901""(protein kinase binding)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043022""(ribosome binding)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:8XSX|rcsb pdb:8Y0W|rcsb pdb:8Y0X|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725|refseq:NP_001952.1|efo:""Orphanet:101112""|panther:PTHR42908(orthology-group)"	"interpro:IPR003836(Glucokinase)|refseq:YP_170250.1|interpro:IPR043129|go:""GO:0004340""(glucokinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005536""(D-glucose binding)|go:""GO:0006096""(glycolytic process)|refseq:WP_003022001.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606	rogid:goPACYqwRR6dZnKimnjt8nxe048177416	intact-crc:FDDD8591FA510E8B|rigid:KES+QdKMrtA/Z9/eXFjUfFrLzM4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P68104	uniprotkb:Q5NFM0	intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|ensembl:ENSP00000330054.2|ensembl:ENSP00000339053.4|ensembl:ENSP00000339063.7|ensembl:ENSP00000348651.3|ensembl:ENSP00000392366.2|ensembl:ENSP00000479055.2|ensembl:ENSP00000503192.1|ensembl:ENSP00000503249.1|ensembl:ENSP00000503823.1|ensembl:ENSP00000504335.1|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|intact:EBI-16423274	intact:EBI-2800168|uniprotkb:A0A0G2RNN7	psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym)	psi-mi:q5nfm0_fratt(display_long)|uniprotkb:FTT_1214c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807122|imex:IM-13779-1106	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000156508.19(gene)|ensembl:ENST00000309268.11(transcript)|ensembl:ENST00000316292.13(transcript)|ensembl:ENST00000331523.7(transcript)|ensembl:ENST00000356303.7(transcript)|ensembl:ENST00000455918.2(transcript)|ensembl:ENST00000615060.5(transcript)|ensembl:ENST00000676710.1(transcript)|ensembl:ENST00000677236.1(transcript)|ensembl:ENST00000678508.1(transcript)|ensembl:ENST00000678702.1(transcript)|mint:P68104|rcsb pdb:3C5J|go:""GO:0000049""(tRNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005853""(eukaryotic translation elongation factor 1 complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006412""(translation)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0019209""(kinase activator activity)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0032587""(ruffle membrane)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0098574""(cytoplasmic side of lysosomal membrane)|go:""GO:1904714""(regulation of chaperone-mediated autophagy)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR050100|interpro:IPR054696|rcsb pdb:6ZMO|rcsb pdb:8G60|rcsb pdb:8G6J|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|reactome:R-HSA-9735869|refseq:XP_011533816.1|dip:DIP-31277N|refseq:NP_001393.1|panther:PTHR23115(orthology-group)"	"interpro:IPR023214|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR000150(Cof protein)|refseq:YP_170172.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0016791""(phosphatase activity)|refseq:WP_003021483.1|interpro:IPR036412"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606	rogid:sGXWuuIontV2yTFO4nOU2nzzlbI177416	intact-crc:FC687F530D588BA1|rigid:UUnxEatOo/+Z57qvpBUHBC3Ea/4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF74	uniprotkb:Q92611	intact:EBI-2796785|uniprotkb:A0A0G2RND4	intact:EBI-1056336|uniprotkb:A8K9C8|ensembl:ENSP00000256497.4|uniprotkb:B4DXP3	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	psi-mi:edem1_human(display_long)|uniprotkb:EDEM1(gene name)|psi-mi:EDEM1(display_short)|uniprotkb:EDEM(gene name synonym)|uniprotkb:KIAA0212(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807129|imex:IM-13779-1108	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"refseq:NP_055489.1|ensembl:ENSG00000134109.11(gene)|ensembl:ENST00000256497.9(transcript)|go:""GO:0004571""(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006058""(mannoprotein catabolic process)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016235""(aggresome)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0036503""(ERAD pathway)|go:""GO:0044322""(endoplasmic reticulum quality control compartment)|go:""GO:0045047""(protein targeting to ER)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0097466""(ubiquitin-dependent glycoprotein ERAD pathway)|go:""GO:1904154""(positive regulation of retrograde protein transport, ER to cytosol)|go:""GO:1904380""(endoplasmic reticulum mannose trimming)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR044674|mint:Q92611|reactome:R-HSA-381038|reactome:R-HSA-901032|panther:PTHR45679(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	rogid:KbPqpha4jyv6T/WPHyqQTAUjD1U9606	intact-crc:E65A824421FD5A81|rigid:l04DpPMwrj1BrKpm364su34vUII	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13639	uniprotkb:Q5NEA2	intact:EBI-352560|uniprotkb:A0A384N6H1|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940.5	intact:EBI-2798906|uniprotkb:A0A0G2RMZ7	psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym)	psi-mi:q5nea2_fratt(display_long)|uniprotkb:FTT_1746(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807115|imex:IM-13779-1107	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000167658.16(gene)|ensembl:ENST00000309311.7(transcript)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0016235""(aggresome)|go:""GO:0019901""(protein kinase binding)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043022""(ribosome binding)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:8XSX|rcsb pdb:8Y0W|rcsb pdb:8Y0X|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725|refseq:NP_001952.1|efo:""Orphanet:101112""|panther:PTHR42908(orthology-group)"	"interpro:IPR004635(Peptidase S49, SppA)|interpro:IPR002142(Peptidase S49)|refseq:YP_170640.1|go:""GO:0006508""(proteolysis)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0016020""(membrane)|interpro:IPR029045|refseq:WP_003022733.1|interpro:IPR047272"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606	rogid:7Gi36muTVeS0Ejv63hRSljZHOy0177416	intact-crc:797E1691FA507D93|rigid:VCLIurlJiVD7jdbgKCIyHLLtpcs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF27	uniprotkb:P30084	intact:EBI-2797283	intact:EBI-719602|uniprotkb:O00739|uniprotkb:Q5VWY1|uniprotkb:Q96H54|ensembl:ENSP00000357535.3	psi-mi:q5nf27_fratt(display_long)|uniprotkb:FTT_1422(locus name)	psi-mi:echm_human(display_long)|uniprotkb:Short-chain enoyl-CoA hydratase(gene name synonym)|uniprotkb:Enoyl-CoA hydratase 1(gene name synonym)|uniprotkb:ECHS1(gene name)|psi-mi:ECHS1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807136|imex:IM-13779-1109	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0008198""(ferrous iron binding)|go:""GO:0031418""(L-ascorbic acid binding)|go:""GO:0031543""(peptidyl-proline dioxygenase activity)|go:""GO:0071456""(cellular response to hypoxia)|interpro:IPR005123(""2OG-Fe(II) oxygenase"")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|refseq:YP_170365.1|interpro:IPR044862|interpro:IPR051559"	"ensembl:ENSG00000127884.5(gene)|ensembl:ENST00000368547.4(transcript)|go:""GO:0004165""(""delta(3)-delta(2)-enoyl-CoA isomerase activity"")|go:""GO:0004300""(enoyl-CoA hydratase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0043956""(3-hydroxypropionyl-CoA dehydratase activity)|go:""GO:0120092""(crotonyl-CoA hydratase activity)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|mint:P30084|rcsb pdb:2HW5|reactome:R-HSA-70895|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|reactome:R-HSA-77352|reactome:R-HSA-9916720|refseq:NP_004083.3|efo:""Orphanet:653880""|panther:PTHR11941(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JC9olxh4wMmKqfNgjUEBhgQ+X0I177416	rogid:zXekfKfyCbjaTVLTdDdAuMgiDco9606	intact-crc:5B218C17ADF70AD1|rigid:7e3Bv6E6Xd2R1TdIgYm3OEDvCzM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:Q13011	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-711968|uniprotkb:Q8WVX0|uniprotkb:Q96EZ9|ensembl:ENSP00000221418.3|ensembl:ENSP00000489530.1|uniprotkb:A8K745	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:ech1_human(display_long)|uniprotkb:ECH1(gene name)|psi-mi:ECH1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807163|imex:IM-13779-1113	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"ensembl:ENSG00000104823.9(gene)|ensembl:ENSG00000282853.2(gene)|ensembl:ENST00000221418.9(transcript)|ensembl:ENST00000634245.2(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0016020""(membrane)|go:""GO:0051750""(""delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity"")|go:""GO:0070062""(extracellular exosome)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|interpro:IPR045002|mint:Q13011|rcsb pdb:2VRE|rcsb pdb:8SK6|reactome:R-HSA-9033241|reactome:R-HSA-9837999|refseq:NP_001389.2|panther:PTHR43149(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:gh0bwdUu9tkSTHWuySCaTXIQGzI9606	intact-crc:C45067F6B5F2E842|rigid:P31aaQdiLTbbgvED9I5cHj6CsKI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40939	uniprotkb:Q5NHX5	intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|uniprotkb:Q53T69|uniprotkb:Q53TA2|ensembl:ENSP00000370023.3	intact:EBI-2801674|uniprotkb:A0A0G2RNV9	psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:q5nhx5_fratt(display_long)|uniprotkb:cdsA(gene name)|psi-mi:cdsA(display_short)|uniprotkb:FTT_0318(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807156|imex:IM-13779-1110	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:243367""|efo:""Orphanet:5""|efo:""Orphanet:746""|ensembl:ENSG00000084754.12(gene)|ensembl:ENST00000380649.8(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0003857""(3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0003985""(acetyl-CoA C-acetyltransferase activity)|go:""GO:0004300""(enoyl-CoA hydratase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016507""(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:""GO:0016509""(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0018812""(3-hydroxyacyl-CoA dehydratase activity)|go:""GO:0032868""(response to insulin)|go:""GO:0035965""(cardiolipin acyl-chain remodeling)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070403""(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|interpro:IPR050136|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:NP_000173.2|panther:PTHR43612(orthology-group)"	"interpro:IPR000374(Phosphatidate cytidylyltransferase)|refseq:YP_169367.1|go:""GO:0004605""(phosphatidate cytidylyltransferase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0016024""(CDP-diacylglycerol biosynthetic process)|refseq:WP_003021609.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606	rogid:j4nia2AICT6hhJFTrk/Er4tDCe8177416	intact-crc:ED8DF368B45E5AF0|rigid:z3zV9wibbewbzn1Uwi2Rrg+4WWU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NTX5	uniprotkb:Q5NIL8	intact:EBI-2807146|uniprotkb:Q5TEG4|uniprotkb:A6NFJ5|uniprotkb:B7Z8S0|uniprotkb:E9PEN7|uniprotkb:E9PR31|uniprotkb:F8W851|uniprotkb:Q5TEF6|uniprotkb:Q5TEF7|uniprotkb:Q5TEG0|uniprotkb:Q9NZ30|uniprotkb:V9HW18|ensembl:ENSP00000436585.1	intact:EBI-2797707|uniprotkb:A0A0G2RN29	psi-mi:echd1_human(display_long)|uniprotkb:ECHDC1(gene name)|psi-mi:ECHDC1(display_short)|uniprotkb:Enoyl-CoA hydratase domain-containing protein 1(gene name synonym)|uniprotkb:Methylmalonyl-CoA decarboxylase(gene name synonym)	psi-mi:q5nil8_fratt(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:FTT_0049(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807143|imex:IM-13779-1112	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002030.1|refseq:NP_001099014.1|refseq:NP_001099015.1|refseq:NP_001132982.1|refseq:NP_060949.2|refseq:XP_005267104.1|refseq:XP_005267105.1|refseq:XP_005267107.1|ensembl:ENSG00000093144.19(gene)|ensembl:ENST00000531967.5(transcript)|go:""GO:0004492""(methyl/ethyl malonyl-CoA decarboxylase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0016831""(carboxy-lyase activity)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|interpro:IPR029045|refseq:XP_016866545.1|panther:PTHR11941(orthology-group)"	"go:""GO:0000166""(nucleotide binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|refseq:YP_169124.1|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010214(Transcription termination factor NusA, C-terminal duplication)|interpro:IPR010213(Transcription termination factor NusA)|interpro:IPR025249|interpro:IPR030842|refseq:WP_003019733.1|interpro:IPR036555"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vZu1Sjy6NcNsdjTh0E3CGM0E7Lc9606	rogid:h3B/JHGk+VSXL6iylODRYTPeDAc177416	intact-crc:EC76DC75CFE9A102|rigid:16Bp6nuCp7H2uPsgog0Z5mqSpMc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2J2	uniprotkb:Q5NHN4	intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158.2|uniprotkb:B7Z4I5|uniprotkb:F5GX05	intact:EBI-2797896	psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym)	"psi-mi:glgb_fratt(display_long)|uniprotkb:""1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase""(gene name synonym)|uniprotkb:FTT_0413c(locus name)|uniprotkb:glgB(gene name)|psi-mi:glgB(display_short)|uniprotkb:""Alpha-(1->4)-glucan branching enzyme""(gene name synonym)|uniprotkb:Glycogen branching enzyme(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807170|imex:IM-13779-1111	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397.18(gene)|ensembl:ENST00000341928.7(transcript)|go:""GO:0002175""(protein localization to paranode region of axon)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006915""(apoptotic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0030054""(cell junction)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0030913""(paranodal junction assembly)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0033270""(paranode region of axon)|go:""GO:0043217""(myelin maintenance)|go:""GO:0044224""(juxtaparanode region of axon)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0071205""(protein localization to juxtaparanode region of axon)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098696""(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0106006""(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N|panther:PTHR23280(orthology-group)"	"go:""GO:0003844""(1,4-alpha-glucan branching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005829""(cytosol)|go:""GO:0005978""(glycogen biosynthetic process)|go:""GO:0043169""(cation binding)|interpro:IPR037439|interpro:IPR044143|refseq:YP_169458.1|interpro:IPR006407(1,4-alpha-glucan branching enzyme, core region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_003020147.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606	rogid:r21IlnrFbxbAaYAD68mDKpyeQwI177416	intact-crc:1F559CDECA76CA1B|rigid:7nhMXwlJyhbcZegQo0ybhgYPgV0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75923	uniprotkb:Q5NIP6	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|ensembl:ENSP00000258104.3|uniprotkb:A0FK00	intact:EBI-2796567	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:gata_fratt(display_long)|uniprotkb:FTT_0020(locus name)|uniprotkb:gatA(gene name)|psi-mi:gatA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807191|imex:IM-13779-1117	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0030315""(T-tubule)|ensembl:ENSG00000135636.16(gene)|ensembl:ENST00000258104.8(transcript)|go:""GO:0002280""(monocyte activation involved in immune response)|go:""GO:0002281""(macrophage activation involved in immune response)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042383""(sarcolemma)|go:""GO:0046928""(regulation of neurotransmitter secretion)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|interpro:IPR055072|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|efo:""Orphanet:178400""|efo:""Orphanet:199329""|efo:""Orphanet:268""|efo:""Orphanet:45448""|panther:PTHR45911(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0030956""(""glutamyl-tRNA(Gln) amidotransferase complex"")|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|interpro:IPR000120(Amidase signature enzyme)|interpro:IPR020556|interpro:IPR023631|interpro:IPR004412(""Glutamyl-tRNA(Gln) amidotransferase A subunit"")|refseq:YP_169096.1|refseq:WP_003022862.1|interpro:IPR036928"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:PXaa59Zvn1xzo0G3HrDFgI8WSJg177416	intact-crc:E604B3F52FE160A3|rigid:qDy2707Vn2vmyUzfUK9uizIBKlY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P51808	uniprotkb:Q5NET8	intact:EBI-743027|uniprotkb:Q6ICS3|ensembl:ENSP00000367841.4	intact:EBI-2797750|uniprotkb:A0A0G2RM76	psi-mi:dylt3_human(display_long)|uniprotkb:T-complex-associated testis-expressed 1-like(gene name synonym)|uniprotkb:Protein 91/23(gene name synonym)|uniprotkb:DYNLT3(gene name)|psi-mi:DYNLT3(display_short)|uniprotkb:TCTE1XL(gene name synonym)|uniprotkb:TCTE1L(gene name synonym)	psi-mi:q5net8_fratt(display_long)|uniprotkb:hrpA(gene name)|psi-mi:hrpA(display_short)|uniprotkb:FTT_1524c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807210|imex:IM-13779-1118	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006511.1|ensembl:ENSG00000165169.11(gene)|ensembl:ENST00000378578.9(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0042802""(identical protein binding)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0051301""(cell division)|go:""GO:0061673""(mitotic spindle astral microtubule)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|panther:PTHR21255(orthology-group)"	"go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170454.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR024590|interpro:IPR010222(RNA helicase, ATP-dependent DEAH box, HrpA type)|interpro:IPR027417|refseq:WP_003022403.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kmjc9zLx9d1OvhucGsEerIzDwwo9606	rogid:dwTrOZ+V/pe0RndqVFMFAdvwFAM177416	intact-crc:327EDAE32B635F2A|rigid:RIRrOi5eikEywQiIQ2g+Zx2//sg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIJ1	uniprotkb:Q86XF0	intact:EBI-2801762	intact:EBI-2807201|uniprotkb:Q6P4I9|uniprotkb:D3DN30|ensembl:ENSP00000319170.2|ensembl:ENSP00000377768.2|ensembl:ENSP00000418415.1|ensembl:ENSP00000480823.1	psi-mi:q5nij1_fratt(display_long)|uniprotkb:sucA(gene name)|psi-mi:sucA(display_short)|uniprotkb:FTT_0076(locus name)	psi-mi:dyr2_human(display_long)|uniprotkb:DHFR2(gene name)|psi-mi:DHFR2(display_short)|uniprotkb:DHFRL1(gene name synonym)|uniprotkb:DHFRP4(gene name synonym)|uniprotkb:Dihydrofolate reductase, mitochondrial(gene name synonym)|uniprotkb:Dihydrofolate reductase-like protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807198|imex:IM-13779-1115	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031717|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|refseq:YP_169151.1|go:""GO:0004591""(""oxoglutarate dehydrogenase (succinyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|interpro:IPR029061|interpro:IPR042179"	"refseq:XP_011510839.1|refseq:NP_001182572.1|refseq:NP_789785.1|ensembl:ENSG00000178700.9(gene)|ensembl:ENST00000314636.3(transcript)|ensembl:ENST00000394221.3(transcript)|ensembl:ENST00000461173.5(transcript)|ensembl:ENST00000619045.1(transcript)|go:""GO:0003729""(mRNA binding)|go:""GO:0004146""(dihydrofolate reductase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0033560""(folate reductase activity)|go:""GO:0046105""(thymidine biosynthetic process)|go:""GO:0046452""(dihydrofolate metabolic process)|go:""GO:0046653""(tetrahydrofolate metabolic process)|go:""GO:0046654""(tetrahydrofolate biosynthetic process)|go:""GO:0046655""(folic acid metabolic process)|go:""GO:0050661""(NADP binding)|interpro:IPR001796(Dihydrofolate reductase region)|interpro:IPR012259(Dihydrofolate reductase)|interpro:IPR024072|reactome:R-HSA-196757|panther:PTHR48069(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dQc/mmfwgUYZL0zzhIJG4HqrrDA177416	rogid:g56U8Ts5j848++E3RANjJkZhQ8o9606	intact-crc:5D3BE0FEA5C2D7D0|rigid:vHli67N+nGCVmltBn03A71QBTyw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43491	uniprotkb:Q5NE83	intact:EBI-1052044|uniprotkb:Q5T4F0|uniprotkb:B4DHI8|uniprotkb:Q68DV2|uniprotkb:E9PPD9|ensembl:ENSP00000338481.3|ensembl:ENSP00000357110.2	intact:EBI-2798034|uniprotkb:A0A0G2RMP3	psi-mi:e41l2_human(display_long)|uniprotkb:Generally expressed protein 4.1(gene name synonym)|uniprotkb:EPB41L2(gene name)|psi-mi:EPB41L2(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 2(gene name synonym)	psi-mi:q5ne83_fratt(display_long)|uniprotkb:FTT_1768c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807177|imex:IM-13779-1116	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001422.1|refseq:NP_001129026.1|refseq:NP_001129027.1|refseq:NP_001239589.1|refseq:XP_011533832.1|refseq:XP_011533836.1|refseq:XP_016865844.1|refseq:XP_016865848.1|refseq:XP_016865849.1|refseq:XP_016865850.1|refseq:XP_016865851.1|dip:DIP-17034N|ensembl:ENSG00000079819.20(gene)|ensembl:ENST00000337057.8(transcript)|ensembl:ENST00000368128.6(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0008091""(spectrin)|go:""GO:0030054""(cell junction)|go:""GO:0030507""(spectrin binding)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0042731""(PH domain binding)|go:""GO:0051301""(cell division)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904778""(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|mint:O43491|reactome:R-HSA-6794361|panther:PTHR23280(orthology-group)"	"go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008843""(endochitinase activity)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:YP_170659.1|interpro:IPR050542"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QvhY6g+bBqTBR8oHl/php27Wb7Y9606	rogid:W2y1WmdkLbyjKn567ANSSuNPpHo177416	intact-crc:3DAEFE5B106E03A8|rigid:vZv34915NaxcxJx9LIKWyjU25h4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75923	uniprotkb:Q5NE94	intact:EBI-2799016|uniprotkb:Q53QY3|uniprotkb:B1PZ70|uniprotkb:B1PZ72|uniprotkb:B1PZ76|uniprotkb:B1PZ79|uniprotkb:B1PZ71|uniprotkb:B1PZ73|uniprotkb:Q8TEL8|uniprotkb:Q09EX5|uniprotkb:Q0H395|uniprotkb:B3KQB9|uniprotkb:B1PZ77|uniprotkb:B1PZ80|uniprotkb:B1PZ81|uniprotkb:B1PZ74|uniprotkb:B1PZ75|uniprotkb:B1PZ78|uniprotkb:O75696|uniprotkb:Q9UEN7|uniprotkb:Q53TD2|ensembl:ENSP00000258104.3|uniprotkb:A0FK00	intact:EBI-2796845|uniprotkb:A0A0G2RPS9	psi-mi:dysf_human(display_long)|uniprotkb:FER1L1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym)|uniprotkb:DYSF(gene name)|psi-mi:DYSF(display_short)	psi-mi:q5ne94_fratt(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:FTT_1754(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807184|imex:IM-13779-1114	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0030315""(T-tubule)|ensembl:ENSG00000135636.16(gene)|ensembl:ENST00000258104.8(transcript)|go:""GO:0002280""(monocyte activation involved in immune response)|go:""GO:0002281""(macrophage activation involved in immune response)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042383""(sarcolemma)|go:""GO:0046928""(regulation of neurotransmitter secretion)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|interpro:IPR055072|rcsb pdb:4CAH|rcsb pdb:4CAI|rcsb pdb:4IHB|rcsb pdb:4IQH|rcsb pdb:7JOF|rcsb pdb:7K6B|rcsb pdb:7KRB|reactome:R-HSA-445355|refseq:NP_001123927.1|refseq:NP_001124448.1|refseq:NP_001124449.1|refseq:NP_001124450.1|refseq:NP_001124451.1|refseq:NP_001124452.1|refseq:NP_001124453.1|refseq:NP_001124454.1|refseq:NP_001124455.1|refseq:NP_001124456.1|refseq:NP_001124457.1|refseq:NP_001124458.1|refseq:NP_001124459.1|refseq:NP_003485.1|efo:""Orphanet:178400""|efo:""Orphanet:199329""|efo:""Orphanet:268""|efo:""Orphanet:45448""|panther:PTHR45911(orthology-group)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0006085""(acetyl-CoA biosynthetic process)|go:""GO:0008959""(phosphate acetyltransferase activity)|interpro:IPR010766(DRTGG)|interpro:IPR016475(Phosphate acetyltransferase, bacteria)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:YP_170648.1|interpro:IPR028979|refseq:WP_003022741.1|interpro:IPR042112|interpro:IPR042113|interpro:IPR050500"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DOlOZvT68wMjkY4tQgaoT2hMQ7U9606	rogid:fYO/qq0vkLuYawMQU9mKbB8hTyo177416	intact-crc:EB23FFF52F4D191F|rigid:cXTJfJ6U5225hsWntxyWryWOF98	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGL8	uniprotkb:Q14204	intact:EBI-2796116	intact:EBI-356015|intact:EBI-4399546|uniprotkb:Q6DKQ7|uniprotkb:Q8WU28|uniprotkb:Q92814|uniprotkb:Q9Y4G5|uniprotkb:B0I1R0|intact:EBI-28969816|ensembl:ENSP00000348965.4	psi-mi:syt_fratt(display_long)|uniprotkb:thrS(gene name)|psi-mi:thrS(display_short)|uniprotkb:Threonyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0817(locus name)	psi-mi:dyhc1_human(display_long)|uniprotkb:DYNC1H1(gene name)|psi-mi:DYNC1H1(display_short)|uniprotkb:DNECL(gene name synonym)|uniprotkb:KIAA0325(gene name synonym)|uniprotkb:DNCH1(gene name synonym)|uniprotkb:DNCL(gene name synonym)|uniprotkb:DHC1(gene name synonym)|uniprotkb:DYHC(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807224|imex:IM-13779-1121	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169824.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|interpro:IPR002320(Threonyl-tRNA synthetase, class IIa)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|refseq:WP_003020750.1|interpro:IPR033728|interpro:IPR036621|interpro:IPR045864|interpro:IPR047246|go:""GO:0000049""(tRNA binding)|go:""GO:0004829""(threonine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006435""(threonyl-tRNA aminoacylation)|go:""GO:0046872""(metal ion binding)"	"efo:""Orphanet:178469""|efo:""Orphanet:209341""|efo:""Orphanet:284232""|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|ensembl:ENSG00000197102.14(gene)|ensembl:ENST00000360184.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005874""(microtubule)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0005938""(cell cortex)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0008090""(retrograde axonal transport)|go:""GO:0008569""(minus-end-directed microtubule motor activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030175""(filopodium)|go:""GO:0030286""(dynein complex)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0032388""(positive regulation of intracellular transport)|go:""GO:0033962""(P-body assembly)|go:""GO:0034063""(stress granule assembly)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0051293""(establishment of spindle localization)|go:""GO:0051301""(cell division)|go:""GO:0051959""(dynein light intermediate chain binding)|go:""GO:0060236""(regulation of mitotic spindle organization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090235""(regulation of metaphase plate congression)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1905832""(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR024317|interpro:IPR024743|interpro:IPR026983|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR054354|mint:Q14204|rcsb pdb:5NUG|rcsb pdb:5OWO|rcsb pdb:6F1T|rcsb pdb:6F1U|rcsb pdb:6F1V|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:7Z8F|rcsb pdb:7Z8G|rcsb pdb:7Z8H|rcsb pdb:7Z8I|rcsb pdb:7Z8J|rcsb pdb:7Z8K|rcsb pdb:7Z8L|rcsb pdb:8DYU|rcsb pdb:8DYV|rcsb pdb:8FCY|rcsb pdb:8FD6|rcsb pdb:8FDT|rcsb pdb:8FDU|rcsb pdb:8PQV|rcsb pdb:8PQW|rcsb pdb:8PQY|rcsb pdb:8PQZ|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PR2|rcsb pdb:8PR3|rcsb pdb:8PTK|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|refseq:NP_001367.2|dip:DIP-37544N|panther:PTHR10676(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:mYG/RO6WmHDnsUAHonnk2kMKPh0177416	rogid:nI5RCxHByU3dxtLnPMPEjJlx1Fc9606	intact-crc:37A7AEF5B00B43E1|rigid:f9ny3TiW7U+i1ag7iiIndZXiOU4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63172	uniprotkb:Q5NFC7	intact:EBI-1176455|uniprotkb:Q15763|uniprotkb:Q5VTU4|ensembl:ENSP00000356056.3	intact:EBI-2798262|uniprotkb:A0A0G2RMU4	psi-mi:dylt1_human(display_long)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym)|uniprotkb:Protein CW-1(gene name synonym)|uniprotkb:DYNLT1(gene name)|psi-mi:DYNLT1(display_short)|uniprotkb:TCTEL1(gene name synonym)|uniprotkb:TCTEX1(gene name synonym)|uniprotkb:TCTEX-1(gene name synonym)	psi-mi:q5nfc7_fratt(display_long)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:FTT_1312c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807217|imex:IM-13779-1119	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006510.1|panther:PTHR21255(orthology-group)|dip:DIP-35251N|ensembl:ENSG00000146425.11(gene)|ensembl:ENST00000367089.8(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007399""(nervous system development)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0019060""(intracellular transport of viral protein in host cell)|go:""GO:0030286""(dynein complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043657""(host cell)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051301""(cell division)|go:""GO:0075521""(microtubule-dependent intracellular transport of viral material towards nucleus)|go:""GO:0099503""(secretory vesicle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|mint:P63172|rcsb pdb:5JPW|rcsb pdb:8J07|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGI|reactome:R-HSA-6798695"	"go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|refseq:YP_170265.1|interpro:IPR027417|refseq:WP_011242277.1|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR041102|interpro:IPR041552"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:RKVyHgf4iNjcY6GfLdIukFOFE+s9606	rogid:U/HaVxzcJmtTpKIFLyjFKRezSA8177416	intact-crc:E7B3E43F9789FB70|rigid:qatCNDcfy2v2sNjWFFizpbvIaSY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFB0	uniprotkb:Q14204	intact:EBI-2796314	intact:EBI-356015|intact:EBI-4399546|uniprotkb:Q6DKQ7|uniprotkb:Q8WU28|uniprotkb:Q92814|uniprotkb:Q9Y4G5|uniprotkb:B0I1R0|intact:EBI-28969816|ensembl:ENSP00000348965.4	"psi-mi:sys_fratt(display_long)|uniprotkb:""Seryl-tRNA(Ser/Sec) synthetase""(gene name synonym)|uniprotkb:FTT_1330(locus name)|uniprotkb:serS(gene name)|psi-mi:serS(display_short)|uniprotkb:Seryl-tRNA synthetase(gene name synonym)"	psi-mi:dyhc1_human(display_long)|uniprotkb:DYNC1H1(gene name)|psi-mi:DYNC1H1(display_short)|uniprotkb:DNECL(gene name synonym)|uniprotkb:KIAA0325(gene name synonym)|uniprotkb:DNCH1(gene name synonym)|uniprotkb:DNCL(gene name synonym)|uniprotkb:DHC1(gene name synonym)|uniprotkb:DYHC(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807231|imex:IM-13779-1120	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004828""(serine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006434""(seryl-tRNA aminoacylation)|go:""GO:0016260""(selenocysteine biosynthetic process)|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR010978(tRNA-binding arm)|refseq:YP_170282.1|refseq:WP_003022075.1|interpro:IPR033729|interpro:IPR045864|interpro:IPR042103"	"efo:""Orphanet:178469""|efo:""Orphanet:209341""|efo:""Orphanet:284232""|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|ensembl:ENSG00000197102.14(gene)|ensembl:ENST00000360184.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005874""(microtubule)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0005938""(cell cortex)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0008090""(retrograde axonal transport)|go:""GO:0008569""(minus-end-directed microtubule motor activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030175""(filopodium)|go:""GO:0030286""(dynein complex)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0032388""(positive regulation of intracellular transport)|go:""GO:0033962""(P-body assembly)|go:""GO:0034063""(stress granule assembly)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0051293""(establishment of spindle localization)|go:""GO:0051301""(cell division)|go:""GO:0051959""(dynein light intermediate chain binding)|go:""GO:0060236""(regulation of mitotic spindle organization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090235""(regulation of metaphase plate congression)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1905832""(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR024317|interpro:IPR024743|interpro:IPR026983|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR054354|mint:Q14204|rcsb pdb:5NUG|rcsb pdb:5OWO|rcsb pdb:6F1T|rcsb pdb:6F1U|rcsb pdb:6F1V|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:7Z8F|rcsb pdb:7Z8G|rcsb pdb:7Z8H|rcsb pdb:7Z8I|rcsb pdb:7Z8J|rcsb pdb:7Z8K|rcsb pdb:7Z8L|rcsb pdb:8DYU|rcsb pdb:8DYV|rcsb pdb:8FCY|rcsb pdb:8FD6|rcsb pdb:8FDT|rcsb pdb:8FDU|rcsb pdb:8PQV|rcsb pdb:8PQW|rcsb pdb:8PQY|rcsb pdb:8PQZ|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PR2|rcsb pdb:8PR3|rcsb pdb:8PTK|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|refseq:NP_001367.2|dip:DIP-37544N|panther:PTHR10676(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:M1krNL4X5Flp/80mQlBn60oe9eI177416	rogid:nI5RCxHByU3dxtLnPMPEjJlx1Fc9606	intact-crc:DBD4DFF5B2EF958E|rigid:vbzUa/YL7cpWc+WM/IFpKAh7q08	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14641	uniprotkb:Q5NHD9	intact:EBI-740850|uniprotkb:Q53XM0|uniprotkb:D3DTN3|ensembl:ENSP00000005340.4	intact:EBI-2807241	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:q5nhd9_fratt(display_long)|uniprotkb:FTT_0522(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807238|imex:IM-13779-1122	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004413.1|ensembl:ENSG00000004975.12(gene)|ensembl:ENST00000005340.10(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001947""(heart looping)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0005109""(frizzled binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007379""(segment specification)|go:""GO:0007507""(heart development)|go:""GO:0008104""(protein localization)|go:""GO:0016235""(aggresome)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022007""(convergent extension involved in neural plate elongation)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0045177""(apical part of cell)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0090103""(cochlea morphogenesis)|go:""GO:0150012""(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|rcsb pdb:8WM9|rcsb pdb:8WMA|rcsb pdb:8WWR|rcsb pdb:8YR7|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|dip:DIP-34433N|panther:PTHR10878(orthology-group)"	"interpro:IPR052916|interpro:IPR029063|interpro:IPR003356(N-6 DNA methylase)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|go:""GO:0003677""(DNA binding)|go:""GO:0008170""(N-methyltransferase activity)|go:""GO:0009007""(""site-specific DNA-methyltransferase (adenine-specific) activity"")|go:""GO:0009307""(DNA restriction-modification system)|go:""GO:0032259""(methylation)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/05	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:Iv2PbwgzPkaDhuJe9BhWtOOeErs177416	intact-crc:1E0472408A9F253D|rigid:U4E2MkinMDOYQhtFt68XwvPmNFw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C005	uniprotkb:Q5NF66	intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066.3|ensembl:ENSP00000345837.5	intact:EBI-2807255|uniprotkb:A0A0G2RP51	psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym)	psi-mi:q5nf66_fratt(display_long)|uniprotkb:fabF(gene name)|psi-mi:fabF(display_short)|uniprotkb:FTT_1377(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807259|imex:IM-13779-1126	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115963.1|refseq:NP_001308138.1|dip:DIP-34476N|ensembl:ENSG00000162961.14(gene)|ensembl:ENST00000295066.3(transcript)|ensembl:ENST00000342166.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0016197""(endosomal transport)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0071339""(MLL1 complex)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|interpro:IPR049629|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|rcsb pdb:7UD5|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922"	"interpro:IPR017568(3-oxoacyl-[acyl-carrier-protein] synthase 2)|interpro:IPR018201|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016039(Thiolase-like)|refseq:YP_170326.1|interpro:IPR020841|go:""GO:0004315""(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006633""(fatty acid biosynthetic process)|refseq:WP_011242279.1|interpro:IPR000794(Beta-ketoacyl synthase)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606	rogid:OLshGCxUDwsNc40F+upNzWjfXts177416	intact-crc:ED1B159A2A1820C7|rigid:CQBzlzvoV6/eQjw9EjOwF24jEp8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UHL4	uniprotkb:Q5NI85	intact:EBI-372284|ensembl:ENSP00000360635.2|uniprotkb:Q969X4|uniprotkb:Q5VSF1|uniprotkb:A8K7U7	intact:EBI-2797607|uniprotkb:A0A0G2RPF9	psi-mi:dpp2_human(display_long)|uniprotkb:DPP7(gene name)|psi-mi:DPP7(display_short)|uniprotkb:DPP2(gene name synonym)|uniprotkb:QPP(gene name synonym)|uniprotkb:Dipeptidyl peptidase II(gene name synonym)|uniprotkb:Dipeptidyl aminopeptidase II(gene name synonym)|uniprotkb:Quiescent cell proline dipeptidase(gene name synonym)|uniprotkb:Dipeptidyl peptidase 7(gene name synonym)	psi-mi:q5ni85_fratt(display_long)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short)|uniprotkb:FTT_0196c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807266|imex:IM-13779-1124	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000176978.16(gene)|ensembl:ENST00000371579.7(transcript)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006508""(proteolysis)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008239""(dipeptidyl-peptidase activity)|go:""GO:0031982""(vesicle)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070008""(serine-type exopeptidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR008758(Peptidase S28)|interpro:IPR029058|interpro:IPR042269|mint:Q9UHL4|rcsb pdb:3JYH|rcsb pdb:3N0T|rcsb pdb:4EBB|reactome:R-HSA-6798695|refseq:NP_037511.2|panther:PTHR11010(orthology-group)"	"go:""GO:0004356""(glutamine synthetase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006542""(glutamine biosynthetic process)|interpro:IPR027302|interpro:IPR027303|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|refseq:YP_169257.1|refseq:WP_003021839.1|interpro:IPR036651|interpro:IPR050292"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MdRmqG846ZvKRuJHrPJ6of20pOU9606	rogid:YcChLfYjBBfwX0EcU0/PtDPQrsU177416	intact-crc:0AB60B14F64BEAE4|rigid:+wgJQ4S/FuNx/CEw5qHS11nGt54	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49005	uniprotkb:Q5NEC0	intact:EBI-372354|ensembl:ENSP00000386105.2|ensembl:ENSP00000395231.1|ensembl:ENSP00000406702.2|ensembl:ENSP00000480186.2|ensembl:ENSP00000514051.1|ensembl:ENSP00000514052.1|ensembl:ENSP00000514053.1|uniprotkb:A4D2J4|uniprotkb:B2R5S4	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:dpod2_human(display_long)|uniprotkb:POLD2(gene name)|psi-mi:POLD2(display_short)|uniprotkb:DNA polymerase delta subunit p50(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807273|imex:IM-13779-1127	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106628.13(gene)|ensembl:ENST00000406581.6(transcript)|ensembl:ENST00000418438.2(transcript)|ensembl:ENST00000452185.5(transcript)|ensembl:ENST00000610533.6(transcript)|ensembl:ENST00000698945.1(transcript)|ensembl:ENST00000698946.1(transcript)|ensembl:ENST00000698947.1(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006271""(DNA strand elongation involved in DNA replication)|go:""GO:0016035""(zeta DNA polymerase complex)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0043625""(delta DNA polymerase complex)|go:""GO:0071897""(DNA biosynthetic process)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR024826|interpro:IPR040663|interpro:IPR041863|mint:P49005|rcsb pdb:3E0J|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|refseq:NP_001120690.1|refseq:NP_001243808.1|refseq:NP_006221.2|panther:PTHR10416(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:B8QUTohwg0iz3s5wdSdmcTGa28I9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:0C028542CA4255DC|rigid:IsdgwOGbhxPk+ItihWirfdTtWWg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60941	uniprotkb:Q5NEB6	intact:EBI-740402|intact:EBI-784159|uniprotkb:O43782|uniprotkb:O60881|uniprotkb:O75538|uniprotkb:Q96AW0|uniprotkb:Q9UE14|uniprotkb:Q9UE15|uniprotkb:Q9UE16|uniprotkb:G5E9F6|uniprotkb:Q86VR4|uniprotkb:B7Z733|uniprotkb:F5GZG4|ensembl:ENSP00000384084.3	intact:EBI-2797029|uniprotkb:A0A0G2RNW9	psi-mi:dtnb_human(display_long)|uniprotkb:DTNB(gene name)|psi-mi:DTNB(display_short)|uniprotkb:Beta-dystrobrevin(gene name synonym)	psi-mi:q5neb6_fratt(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:FTT_1724c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807248|imex:IM-13779-1123	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001243232.1|refseq:NP_068707.1|refseq:NP_149159.2|refseq:NP_149160.1|refseq:NP_899204.1|refseq:NP_001243237.1|refseq:NP_899205.1|refseq:NP_001307861.1|refseq:NP_001307862.1|refseq:NP_001307863.1|refseq:NP_001307864.1|refseq:NP_001307865.1|ensembl:ENSG00000138101.20(gene)|ensembl:ENST00000406818.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0014069""(postsynaptic density)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030425""(dendrite)|go:""GO:0045202""(synapse)|go:""GO:0060077""(inhibitory synapse)|go:""GO:0099536""(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|interpro:IPR050774|mint:O60941|panther:PTHR12268(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:1990281""(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|refseq:YP_170626.1|refseq:WP_003022695.1|interpro:IPR051906"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/yB9vgxJOii2Uk4riTNLOhf9gUk9606	rogid:rzu9m+ahxwjrbytyPusL6ALCJRw177416	intact-crc:43B9B066B9747E50|rigid:JhsXR+fCmMHWsK1e8r/vYFpjzSA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NF50	uniprotkb:Q5NHD1	intact:EBI-2548605|uniprotkb:B7ZLP0|uniprotkb:E9PH09|uniprotkb:A2A350|uniprotkb:A2BDF2|uniprotkb:A4FU78|uniprotkb:Q3MV16|uniprotkb:Q5JPJ1|uniprotkb:Q8TEP1|uniprotkb:Q8WUY2|uniprotkb:Q9BYJ5|uniprotkb:Q9H1Q2|uniprotkb:Q9H1Q3|uniprotkb:Q9H308|uniprotkb:Q9H7P2|ensembl:ENSP00000394888.3|intact:EBI-11070681	intact:EBI-2799605|uniprotkb:A0A0G2RPC0	psi-mi:dock8_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:q5nhd1_fratt(display_long)|uniprotkb:grxC(gene name)|psi-mi:grxC(display_short)|uniprotkb:FTT_0532c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807280|imex:IM-13779-1125	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000107099.18(gene)|ensembl:ENST00000432829.7(transcript)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0031252""(cell leading edge)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0061485""(memory T cell proliferation)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:1903905""(positive regulation of establishment of T cell polarity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000406""(positive regulation of T cell migration)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|interpro:IPR046769|interpro:IPR046770|interpro:IPR046773|mint:Q8NF50|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-983231|refseq:NP_001177387.1|refseq:NP_001180465.1|refseq:NP_982272.2|refseq:XP_011516347.1|refseq:XP_011516349.1|refseq:XP_011516350.1|refseq:XP_016870662.1|efo:""Orphanet:178469""|efo:""Orphanet:217390""|panther:PTHR23317(orthology-group)"	"interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR002109(Glutaredoxin)|interpro:IPR014025(Glutaredoxin subgroup)|interpro:IPR000358(Ribonucleotide reductase)|refseq:YP_169561.1|go:""GO:0004748""(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:""GO:0009263""(deoxyribonucleotide biosynthetic process)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_003023235.1|interpro:IPR036249|interpro:IPR011900(Glutaredoxin, GrxC)|interpro:IPR033909|interpro:IPR012348(Ribonucleotide reductase-related)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4ENO+3IOKfCUicfg8fxFQbwf4fg9606	rogid:Zlpot7hmLVzAffGINLtgVgDpcoA177416	intact-crc:25206E8285A026B0|rigid:ypyJLA6ECN2VbVSy9G5k79WEjCc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31040	uniprotkb:Q5NI74	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q8IW48|uniprotkb:Q59GW8|uniprotkb:A8K5J6|ensembl:ENSP00000264932.6	intact:EBI-2797356|uniprotkb:A0A0G2RNT1	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)|uniprotkb:Malate dehydrogenase [quinone] flavoprotein subunit(gene name synonym)	psi-mi:q5ni74_fratt(display_long)|uniprotkb:FTT_0209c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807315|imex:IM-13779-1131	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000073578.18(gene)|ensembl:ENST00000264932.11(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006105""(succinate metabolic process)|go:""GO:0006121""(mitochondrial electron transport, succinate to ubiquinone)|go:""GO:0007399""(nervous system development)|go:""GO:0008177""(""succinate dehydrogenase (quinone) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045273""(""respiratory chain complex II (succinate dehydrogenase)"")|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR030664|interpro:IPR036188|interpro:IPR037099|mint:P31040|rcsb pdb:6VAX|rcsb pdb:8DYD|rcsb pdb:8DYE|rcsb pdb:8GS8|reactome:R-HSA-611105|reactome:R-HSA-71403|reactome:R-HSA-9854311|refseq:NP_001281261.1|refseq:NP_004159.2|efo:""Orphanet:154""|efo:""Orphanet:29072""|efo:""Orphanet:3208""|efo:""Orphanet:44890""|dip:DIP-45851N|panther:PTHR11632(orthology-group)|ensembl:ENSP00000264932.6|ensembl:ENST00000510361.5|ensembl:ENSP00000427703.1"	"go:""GO:0007155""(cell adhesion)|go:""GO:0030001""(metal ion transport)|go:""GO:0046872""(metal ion binding)|interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006129(Adhesin B)|refseq:YP_169268.1|refseq:WP_003017523.1|interpro:IPR050492"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	rogid:SNzKG6SXy0yUlUpZyU9sv3eNyRk177416	intact-crc:64ED2758D0587B7C|rigid:qhUtBN0c8LOi1pioT+SZCfP5WuQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y394	uniprotkb:Q5NES9	intact:EBI-1387800|uniprotkb:Q9UKU2|uniprotkb:B2R896|ensembl:ENSP00000216500.5|ensembl:ENSP00000451882.1	intact:EBI-2799997|uniprotkb:A0A0G2RNU2	psi-mi:dhrs7_human(display_long)|uniprotkb:DHRS7(gene name)|psi-mi:DHRS7(display_short)|uniprotkb:RETSDR4(gene name synonym)|uniprotkb:SDR34C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 34C member 1(gene name synonym)|uniprotkb:CGI-86(orf name)|uniprotkb:UNQ285/PRO3448(orf name)|uniprotkb:DHRS7A(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase 4(gene name synonym)	psi-mi:q5nes9_fratt(display_long)|uniprotkb:FTT_1534c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807322|imex:IM-13779-1129	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057113.1|refseq:NP_001309209.1|panther:PTHR44269(orthology-group)|ensembl:ENSG00000100612.14(gene)|ensembl:ENST00000216500.9(transcript)|ensembl:ENST00000557185.6(transcript)|go:""GO:0004090""(""carbonyl reductase (NADPH) activity"")|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0052650""(""all-trans-retinol dehydrogenase (NADP+) activity"")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|interpro:IPR053011|mint:Q9Y394"	"interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|refseq:YP_170463.1|go:""GO:0009435""(NAD biosynthetic process)|go:""GO:0047280""(nicotinamide phosphoribosyltransferase activity)|refseq:WP_003018116.1|interpro:IPR036068|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR041525|interpro:IPR041529"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OcTvozRJMb/lmA0bzcIcNpWIbYE9606	rogid:0+HtF7EvtGUcHmfq6JdVWnUFZs8177416	intact-crc:3867B3EBDBC8553B|rigid:x/rSdE33Tbf3acVR5qTUNefjvDQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7L7V1	uniprotkb:Q5NID2	intact:EBI-2807297|uniprotkb:Q9NV74|uniprotkb:Q96NY1|uniprotkb:Q9NVJ7|uniprotkb:Q9NSL5|uniprotkb:Q9H769|uniprotkb:Q5T3L5|uniprotkb:Q9BUN0|uniprotkb:Q5T3L0|uniprotkb:A8MSV2|uniprotkb:Q49AG5|uniprotkb:D3DRF9|ensembl:ENSP00000284690.3	intact:EBI-2796292	psi-mi:dhx32_human(display_long)|uniprotkb:DHX32(gene name)|psi-mi:DHX32(display_short)|uniprotkb:DDX32(gene name synonym)|uniprotkb:DEAD/H box 32(gene name synonym)|uniprotkb:DEAD/H helicase-like protein 1(gene name synonym)|uniprotkb:DEAH box protein 32(gene name synonym)|uniprotkb:HuDDX32(gene name synonym)	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807294|imex:IM-13779-1128	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060650.2|ensembl:ENSG00000089876.12(gene)|ensembl:ENST00000284690.4(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR048333|mint:Q7L7V1|refseq:XP_016871893.1|refseq:XP_016871894.1|panther:PTHR18934(orthology-group)"	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IQFcD75pd5R0uajIotdMRpGXVeI9606	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	intact-crc:5A2BE7B43690EF53|rigid:D/3fIX8+86nFsoKNG/tZQ2uTVlw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00367	uniprotkb:Q5NG93	intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865.4|uniprotkb:B3KV55|uniprotkb:B4DGN5	intact:EBI-2797241|uniprotkb:A0A0G2RNP8	psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym)	psi-mi:q5ng93_fratt(display_long)|uniprotkb:xthA(gene name)|psi-mi:xthA(display_short)|uniprotkb:FTT_0959c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807329|imex:IM-13779-1132	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:35878""|ensembl:ENSG00000148672.10(gene)|ensembl:ENST00000277865.5(transcript)|go:""GO:0004352""(""glutamate dehydrogenase (NAD+) activity"")|go:""GO:0004353""(""glutamate dehydrogenase [NAD(P)+] activity"")|go:""GO:0004354""(""glutamate dehydrogenase (NADP+) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006538""(glutamate catabolic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043531""(ADP binding)|go:""GO:0070403""(NAD+ binding)|go:""GO:0070728""(L-leucine binding)|go:""GO:0072350""(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|interpro:IPR046346|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|rcsb pdb:7UZM|rcsb pdb:8KGY|rcsb pdb:8SK8|rcsb pdb:8W4J|reactome:R-HSA-2151201|reactome:R-HSA-8964539|reactome:R-HSA-9837999|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|refseq:NP_005262.1|panther:PTHR11606(orthology-group)"	"go:""GO:0003906""(""DNA-(apurinic or apyrimidinic site) endonuclease activity"")|go:""GO:0006284""(base-excision repair)|go:""GO:0008081""(phosphoric diester hydrolase activity)|go:""GO:0008311""(double-stranded DNA 3'-5' DNA exonuclease activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR004808(Exodeoxyribonuclease III xth)|refseq:YP_169949.1|refseq:WP_003021031.1|interpro:IPR036691"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606	rogid:UmV6e4+lqB1TTnnIHyqtaomo34c177416	intact-crc:42FA9124CB4047F5|rigid:M/89eAfgIKEi6Dl4vHWhLZXFHqE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NP97	uniprotkb:Q5NIP8	intact:EBI-372128|ensembl:ENSP00000349679.2|uniprotkb:Q5TC72|uniprotkb:Q96IV3|uniprotkb:Q9NQM2|uniprotkb:B1AKR5	intact:EBI-2796698	psi-mi:dlrb1_human(display_long)|uniprotkb:DYNLRB1(gene name)|psi-mi:DYNLRB1(display_short)|uniprotkb:BITH(gene name synonym)|uniprotkb:DNLC2A(gene name synonym)|uniprotkb:HSPC162(orf name)|uniprotkb:Dynein light chain 2A, cytoplasmic(gene name synonym)|uniprotkb:Dynein-associated protein Km23(gene name synonym)|uniprotkb:Bithoraxoid-like protein(gene name synonym)|uniprotkb:DNCL2A(gene name synonym)|uniprotkb:ROBLD1(gene name synonym)|uniprotkb:Roadblock domain-containing protein 1(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807287|imex:IM-13779-1130	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000125971.18(gene)|ensembl:ENST00000357156.7(transcript)|go:""GO:0003777""(microtubule motor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005874""(microtubule)|go:""GO:0005929""(cilium)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007632""(visual behavior)|go:""GO:0016020""(membrane)|go:""GO:0030286""(dynein complex)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0097542""(ciliary tip)|interpro:IPR004942(Dynein light chain-related)|interpro:IPR016561(Dynein light chain, roadblock-type)|mint:Q9NP97|rcsb pdb:1Z09|rcsb pdb:2B95|rcsb pdb:2E8J|rcsb pdb:2HZ5|rcsb pdb:6F1T|rcsb pdb:6F1Z|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7Z8F|rcsb pdb:8J07|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGG|rcsb pdb:8RGH|reactome:R-HSA-5620924|refseq:NP_054902.1|refseq:NP_001268656.1|refseq:NP_001268657.1|refseq:NP_001268658.1|refseq:NP_808852.1|panther:PTHR10779(orthology-group)"	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jUoW69LtAjTLlqS8J8KH7nImOSQ9606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:F3E338F6B6B80803|rigid:GTASIrBHkRWBxZkytO5TPk1OVyQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17844	uniprotkb:Q5NET1	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792.5|ensembl:ENSP00000403085.3|ensembl:ENSP00000463168.2|ensembl:ENSP00000464337.2|ensembl:ENSP00000504794.1	intact:EBI-2799872|uniprotkb:A0A0G2RMN9	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:q5net1_fratt(display_long)|uniprotkb:fadA(gene name)|psi-mi:fadA(display_short)|uniprotkb:FTT_1531(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807364|imex:IM-13779-1136	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|ensembl:ENSG00000108654.16(gene)|ensembl:ENST00000225792.10(transcript)|ensembl:ENST00000450599.7(transcript)|ensembl:ENST00000577922.6(transcript)|ensembl:ENST00000585111.2(transcript)|ensembl:ENST00000676785.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0009299""(mRNA transcription)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0031053""(primary miRNA processing)|go:""GO:0035500""(MH2 domain binding)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0043517""(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0045069""(regulation of viral genome replication)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0046332""(SMAD binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048511""(rhythmic process)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0060765""(regulation of androgen receptor signaling pathway)|go:""GO:0061614""(miRNA transcription)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0070878""(primary miRNA binding)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2001014""(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|dip:DIP-29844N|panther:PTHR47958(orthology-group)|ensembl:ENSP00000225792.5|ensembl:ENSP00000403085.3|ensembl:ENSP00000464337.2|ensembl:ENSP00000463168.2|ensembl:ENSP00000504794.1"	"interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020615|interpro:IPR020610|interpro:IPR020617|interpro:IPR020613|interpro:IPR020616|refseq:YP_170461.1|go:""GO:0003988""(acetyl-CoA C-acyltransferase activity)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0010124""(phenylacetate catabolic process)|refseq:WP_003014953.1|interpro:IPR050215"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	rogid:G7eXVKsS/V6cDu1kiIN/rXBheXs177416	intact-crc:47EF6FC2B9D1A04B|rigid:y+F4ssJAIY/e9P1ohfKa0NdDIoA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF74	uniprotkb:Q8IY21	intact:EBI-2796785|uniprotkb:A0A0G2RND4	intact:EBI-2807346|uniprotkb:Q9NVE3|uniprotkb:Q6PK35|ensembl:ENSP00000377344.3	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	psi-mi:ddx60_human(display_long)|uniprotkb:DDX60(gene name)|psi-mi:DDX60(display_short)|uniprotkb:DEAD box protein 60(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807343|imex:IM-13779-1135	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"refseq:NP_060101.3|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|ensembl:ENSG00000137628.18(gene)|ensembl:ENST00000393743.8(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0009615""(response to virus)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045087""(innate immune response)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0051607""(defense response to virus)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1900245""(positive regulation of MDA-5 signaling pathway)|go:""GO:1900246""(positive regulation of RIG-I signaling pathway)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR052431|interpro:IPR055124|mint:Q8IY21|panther:PTHR44533(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	rogid:5C+KnW/f8OSC2ftQ3EoSEonBbn09606	intact-crc:9E9CC2C0EA13D95E|rigid:uYteOQfO7lE6xzsc+GPiDAnsF54	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF50	uniprotkb:P00367	intact:EBI-2799423|uniprotkb:A0A0G2RN72	intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865.4|uniprotkb:B3KV55|uniprotkb:B4DGN5	psi-mi:q5nf50_fratt(display_long)|uniprotkb:Exonuclease V subunit RecC(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecC(gene name synonym)|uniprotkb:recC(gene name)|psi-mi:recC(display_short)|uniprotkb:FTT_1397c(locus name)	psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807336|imex:IM-13779-1133	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006697(Exodeoxyribonuclease V, RecC subunit)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|refseq:YP_170342.1|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|refseq:WP_003022201.1|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR041500"	"efo:""Orphanet:35878""|ensembl:ENSG00000148672.10(gene)|ensembl:ENST00000277865.5(transcript)|go:""GO:0004352""(""glutamate dehydrogenase (NAD+) activity"")|go:""GO:0004353""(""glutamate dehydrogenase [NAD(P)+] activity"")|go:""GO:0004354""(""glutamate dehydrogenase (NADP+) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006538""(glutamate catabolic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043531""(ADP binding)|go:""GO:0070403""(NAD+ binding)|go:""GO:0070728""(L-leucine binding)|go:""GO:0072350""(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|interpro:IPR046346|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|rcsb pdb:7UZM|rcsb pdb:8KGY|rcsb pdb:8SK8|rcsb pdb:8W4J|reactome:R-HSA-2151201|reactome:R-HSA-8964539|reactome:R-HSA-9837999|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|refseq:NP_005262.1|panther:PTHR11606(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dix8s5jOlPbCloD4EjJhnk5rYr4177416	rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606	intact-crc:2F6BE024CBA6D224|rigid:nIAbKuEUin//6w4f30gj6uYIKQw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17844	uniprotkb:Q5NHY6	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792.5|ensembl:ENSP00000403085.3|ensembl:ENSP00000463168.2|ensembl:ENSP00000464337.2|ensembl:ENSP00000504794.1	intact:EBI-2796153	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:sye_fratt(display_long)|uniprotkb:gltX(gene name)|psi-mi:gltX(display_short)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0307(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807357|imex:IM-13779-1134	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|ensembl:ENSG00000108654.16(gene)|ensembl:ENST00000225792.10(transcript)|ensembl:ENST00000450599.7(transcript)|ensembl:ENST00000577922.6(transcript)|ensembl:ENST00000585111.2(transcript)|ensembl:ENST00000676785.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0009299""(mRNA transcription)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0031053""(primary miRNA processing)|go:""GO:0035500""(MH2 domain binding)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0043517""(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0045069""(regulation of viral genome replication)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0046332""(SMAD binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048511""(rhythmic process)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0060765""(regulation of androgen receptor signaling pathway)|go:""GO:0061614""(miRNA transcription)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0070878""(primary miRNA binding)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2001014""(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|dip:DIP-29844N|panther:PTHR47958(orthology-group)|ensembl:ENSP00000225792.5|ensembl:ENSP00000403085.3|ensembl:ENSP00000464337.2|ensembl:ENSP00000463168.2|ensembl:ENSP00000504794.1"	"refseq:YP_169356.1|interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004527(Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020058|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:WP_003021625.1|interpro:IPR033910|interpro:IPR045462|interpro:IPR049940|go:""GO:0000049""(tRNA binding)|go:""GO:0004818""(glutamate-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006424""(glutamyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	rogid:6DvyR/b9UNDoFX+nMfvtqGvLXt4177416	intact-crc:D69152C2B8449714|rigid:zo51JJ+BNX79QfWTGc1EOoDUzdo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92841	uniprotkb:Q5NGF1	intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536.2	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym)	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807378|imex:IM-13779-1139	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006377.2|dip:DIP-29843N|ensembl:ENSG00000100201.23(gene)|ensembl:ENST00000403230.3(transcript)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0002376""(immune system process)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006364""(rRNA processing)|go:""GO:0006396""(RNA processing)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0010586""(miRNA metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051607""(defense response to virus)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2001014""(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR046330|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|panther:PTHR47958(orthology-group)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/24	rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	intact-crc:A86B64665CE22A49|rigid:CaSBugC9zw7PLYH3z+7vXC8T6Zs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7L014	uniprotkb:Q5NF50	intact:EBI-2555356|uniprotkb:Q96EI0|uniprotkb:O94894|uniprotkb:Q9Y658|ensembl:ENSP00000346236.4	intact:EBI-2799423|uniprotkb:A0A0G2RN72	psi-mi:ddx46_human(display_long)|uniprotkb:KIAA0801(gene name synonym)|uniprotkb:DEAD box protein 46(gene name synonym)|uniprotkb:PRP5 homolog(gene name synonym)|uniprotkb:DDX46(gene name)|psi-mi:DDX46(display_short)	psi-mi:q5nf50_fratt(display_long)|uniprotkb:Exonuclease V subunit RecC(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecC(gene name synonym)|uniprotkb:recC(gene name)|psi-mi:recC(display_short)|uniprotkb:FTT_1397c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807371|imex:IM-13779-1137	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055644.2|ensembl:ENSG00000145833.16(gene)|ensembl:ENST00000354283.8(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0001650""(fibrillar center)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005684""(U2-type spliceosomal complex)|go:""GO:0005686""(U2 snRNP)|go:""GO:0015030""(Cajal body)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1903241""(U2-type prespliceosome assembly)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q7L014|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7EVO|rcsb pdb:7Q3L|rcsb pdb:7VPX|reactome:R-HSA-72163|refseq:NP_001287789.1|panther:PTHR24031(orthology-group)"	"interpro:IPR006697(Exodeoxyribonuclease V, RecC subunit)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|refseq:YP_170342.1|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|refseq:WP_003022201.1|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR041500"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:spn1NOUIO6XjH4RRbtPsBgR5Wk09606	rogid:dix8s5jOlPbCloD4EjJhnk5rYr4177416	intact-crc:B5DF391FE8AFA19B|rigid:BcbkdDhHDH+elYlV8d/wty83gAs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH53	uniprotkb:Q15038	intact:EBI-2807395	intact:EBI-724310|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|ensembl:ENSP00000394699.2|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	"psi-mi:miab_fratt(display_long)|uniprotkb:miaB(gene name)|psi-mi:miaB(display_short)|uniprotkb:""tRNA-i(6)A37 methylthiotransferase""(gene name synonym)|uniprotkb:FTT_0618c(locus name)|uniprotkb:""(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB""(gene name synonym)"	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)|uniprotkb:Proline-rich transcript in brain protein(gene name synonym)|uniprotkb:PRTB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807392|imex:IM-13779-1140	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169639.1|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR020612|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR006463(""tRNA-i(6)A37 modification enzyme MiaB"")|interpro:IPR007197(Radical SAM)|interpro:IPR023404|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|go:""GO:0005829""(cytosol)|go:""GO:0035597""(""tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity"")|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_003023392.1|interpro:IPR038135"	"refseq:NP_001129736.1|refseq:NP_055579.1|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|mint:Q15038|ensembl:ENSG00000183283.16(gene)|ensembl:ENST00000412716.8(transcript)|go:""GO:0002039""(p53 binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016604""(nuclear body)|go:""GO:0016607""(nuclear speck)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034063""(stress granule assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0050699""(WW domain binding)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1905636""(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR022730|refseq:NP_001129738.1|panther:PTHR31638(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:btL908UHd/1HSbxXxBUj7+JkSL8177416	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:AE51A8FCD9344B70|rigid:fNN51y6cwjNR8YATFPNzOcCBRTE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIJ1	uniprotkb:O43237	intact:EBI-2801762	intact:EBI-715294|uniprotkb:Q8TAT3|uniprotkb:A8K6V1|uniprotkb:B4DZP4|ensembl:ENSP00000258198.2	psi-mi:q5nij1_fratt(display_long)|uniprotkb:sucA(gene name)|psi-mi:sucA(display_short)|uniprotkb:FTT_0076(locus name)	psi-mi:dc1l2_human(display_long)|uniprotkb:Dynein light intermediate chain 2, cytosolic(gene name synonym)|uniprotkb:LIC53/55(gene name synonym)|uniprotkb:DYNC1LI2(gene name)|psi-mi:DYNC1LI2(display_short)|uniprotkb:LIC2(gene name synonym)|uniprotkb:DNCLI2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807385|imex:IM-13779-1138	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031717|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|refseq:YP_169151.1|go:""GO:0004591""(""oxoglutarate dehydrogenase (succinyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|interpro:IPR029061|interpro:IPR042179"	"refseq:NP_006132.1|refseq:NP_001273086.1|ensembl:ENSG00000135720.13(gene)|ensembl:ENST00000258198.7(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000776""(kinetochore)|go:""GO:0005524""(ATP binding)|go:""GO:0005770""(late endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0016020""(membrane)|go:""GO:0030286""(dynein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0045504""(dynein heavy chain binding)|go:""GO:0051642""(centrosome localization)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|interpro:IPR027417|mint:O43237|rcsb pdb:6F1T|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:7Z8F|rcsb pdb:7Z8I|rcsb pdb:7Z8J|rcsb pdb:7Z8K|rcsb pdb:7Z8L|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PR2|rcsb pdb:8PR3|rcsb pdb:8PTK|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|panther:PTHR12688(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dQc/mmfwgUYZL0zzhIJG4HqrrDA177416	rogid:WUEd3zgPhcKEe10gtoJ+okX8Zps9606	intact-crc:FD7D6D0045427992|rigid:4PO6iwBmMKyFNg23oqvfbFkQzBA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFJ3	uniprotkb:P08174	intact:EBI-2807437	intact:EBI-1033846|uniprotkb:P09679|uniprotkb:P78361|ensembl:ENSP00000356031.4|uniprotkb:B1AP14|uniprotkb:D3DT83|uniprotkb:D3DT84|uniprotkb:E7ER69|uniprotkb:Q14UF2|uniprotkb:Q14UF3|uniprotkb:Q14UF4|uniprotkb:Q14UF5|uniprotkb:Q14UF6	psi-mi:glya_fratt(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:FTT_1241(locus name)	psi-mi:daf_human(display_long)|uniprotkb:CD55(gene name)|psi-mi:CD55(display_short)|uniprotkb:CR(gene name synonym)|uniprotkb:DAF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807434|imex:IM-13779-1144	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR049943|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR019798|refseq:YP_170199.1|go:""GO:0004372""(glycine hydroxymethyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0019264""(glycine biosynthetic process from serine)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0035999""(tetrahydrofolate interconversion)|interpro:IPR039429|refseq:WP_003021543.1"	"ensembl:ENSG00000196352.18(gene)|ensembl:ENST00000367064.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001618""(virus receptor activity)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0008289""(lipid binding)|go:""GO:0009986""(cell surface)|efo:""Orphanet:566175""|go:""GO:0030133""(transport vesicle)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031664""(regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045730""(respiratory burst)|go:""GO:0045916""(negative regulation of complement activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098552""(side of membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|go:""GO:2000563""(positive regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR050350|mint:P08174|rcsb pdb:1H03|rcsb pdb:1H04|rcsb pdb:1H2P|rcsb pdb:1H2Q|rcsb pdb:1M11|rcsb pdb:1NWV|rcsb pdb:1OJV|rcsb pdb:1OJW|rcsb pdb:1OJY|rcsb pdb:1OK1|rcsb pdb:1OK2|rcsb pdb:1OK3|rcsb pdb:1OK9|rcsb pdb:1UOT|rcsb pdb:1UPN|rcsb pdb:2C8I|rcsb pdb:2QZD|rcsb pdb:2QZF|rcsb pdb:2QZH|rcsb pdb:3IYP|rcsb pdb:3J24|rcsb pdb:5FOA|rcsb pdb:6ILJ|rcsb pdb:6ILK|rcsb pdb:6LA5|rcsb pdb:7C9W|rcsb pdb:7DO4|rcsb pdb:7VY5|rcsb pdb:7VY6|rcsb pdb:8B8R|rcsb pdb:8K9R|rcsb pdb:8K9T|reactome:R-HSA-373080|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|refseq:NP_000565.1|refseq:NP_001108224.1|refseq:NP_001287832.1|refseq:NP_001287833.1|panther:PTHR19325(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YGV3lD5dnE8X8rx9qJdzXtxEdhM177416	rogid:5sa2K9j8EDzc3zJAe72+YVHTM/o9606	intact-crc:7B389B7A9C805423|rigid:FIBRXOs3hSQCLsu0xNO+GtMieW4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P219	uniprotkb:Q5NF52	intact:EBI-2807406|uniprotkb:Q86SX7|uniprotkb:Q7L1M2|uniprotkb:Q8IYG8|uniprotkb:Q69YK1|ensembl:ENSP00000374507.6	intact:EBI-2801584|uniprotkb:A0A0G2RNY6	psi-mi:daple_human(display_long)|uniprotkb:CCDC88C(gene name)|psi-mi:CCDC88C(display_short)|uniprotkb:DAPLE(gene name synonym)|uniprotkb:KIAA1509(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 88C(gene name synonym)|uniprotkb:Dvl-associating protein with a high frequency of leucine residues(gene name synonym)|uniprotkb:Hook-related protein 2(gene name synonym)	psi-mi:q5nf52_fratt(display_long)|uniprotkb:FTT_1395c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807403|imex:IM-13779-1141	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000015133.20(gene)|ensembl:ENST00000389857.11(transcript)|go:""GO:0001578""(microtubule bundle formation)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0003383""(apical constriction)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005109""(frizzled binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0007026""(negative regulation of microtubule depolymerization)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008017""(microtubule binding)|go:""GO:0030054""(cell junction)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030705""(cytoskeleton-dependent intracellular transport)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031648""(protein destabilization)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044782""(cilium organization)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051959""(dynein light intermediate chain binding)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0120197""(mucociliary clearance)|go:""GO:1902691""(respiratory basal cell differentiation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR043936|mint:Q9P219|reactome:R-HSA-5368598|refseq:NP_001073883.2|efo:""Orphanet:269510""|efo:""Orphanet:423275""|panther:PTHR18947(orthology-group)"	"interpro:IPR007421(ATPase associated with various cellular activities, AAA-4)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:YP_170340.1|interpro:IPR025831|go:""GO:0004386""(helicase activity)|refseq:WP_003022198.1|interpro:IPR038461|interpro:IPR038475|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YAtHk2OXKhOgcCerBWS0ObVTLks9606	rogid:jXG9mH+7eRZFsFBHYoB3CjJacm0177416	intact-crc:C0228B995F958C33|rigid:cO0ULZtPgAlN5SqhpXK2AdbbJ4E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08174	uniprotkb:Q5NGT6	intact:EBI-1033846|uniprotkb:P09679|uniprotkb:P78361|ensembl:ENSP00000356031.4|uniprotkb:B1AP14|uniprotkb:D3DT83|uniprotkb:D3DT84|uniprotkb:E7ER69|uniprotkb:Q14UF2|uniprotkb:Q14UF3|uniprotkb:Q14UF4|uniprotkb:Q14UF5|uniprotkb:Q14UF6	intact:EBI-2797196|uniprotkb:A0A0G2RQ43	psi-mi:daf_human(display_long)|uniprotkb:CD55(gene name)|psi-mi:CD55(display_short)|uniprotkb:CR(gene name synonym)|uniprotkb:DAF(gene name synonym)	psi-mi:q5ngt6_fratt(display_long)|uniprotkb:FTT_0745c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807427|imex:IM-13779-1142	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000196352.18(gene)|ensembl:ENST00000367064.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001618""(virus receptor activity)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0008289""(lipid binding)|go:""GO:0009986""(cell surface)|efo:""Orphanet:566175""|go:""GO:0030133""(transport vesicle)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031664""(regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045730""(respiratory burst)|go:""GO:0045916""(negative regulation of complement activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098552""(side of membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|go:""GO:2000563""(positive regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR050350|mint:P08174|rcsb pdb:1H03|rcsb pdb:1H04|rcsb pdb:1H2P|rcsb pdb:1H2Q|rcsb pdb:1M11|rcsb pdb:1NWV|rcsb pdb:1OJV|rcsb pdb:1OJW|rcsb pdb:1OJY|rcsb pdb:1OK1|rcsb pdb:1OK2|rcsb pdb:1OK3|rcsb pdb:1OK9|rcsb pdb:1UOT|rcsb pdb:1UPN|rcsb pdb:2C8I|rcsb pdb:2QZD|rcsb pdb:2QZF|rcsb pdb:2QZH|rcsb pdb:3IYP|rcsb pdb:3J24|rcsb pdb:5FOA|rcsb pdb:6ILJ|rcsb pdb:6ILK|rcsb pdb:6LA5|rcsb pdb:7C9W|rcsb pdb:7DO4|rcsb pdb:7VY5|rcsb pdb:7VY6|rcsb pdb:8B8R|rcsb pdb:8K9R|rcsb pdb:8K9T|reactome:R-HSA-373080|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|refseq:NP_000565.1|refseq:NP_001108224.1|refseq:NP_001287832.1|refseq:NP_001287833.1|panther:PTHR19325(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR006726(Fusaric acid resistance protein conserved region)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5sa2K9j8EDzc3zJAe72+YVHTM/o9606	rogid:IBdu8fu+XlWmfYIoDrG9CYq1qkc177416	intact-crc:7D5BEA7A9DA9B4EC|rigid:WV1fWZkEOFo98WXdSg3NL80YbeM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14118	uniprotkb:Q5NID2	intact:EBI-1755945|uniprotkb:A8K6M7|uniprotkb:Q969J9|ensembl:ENSP00000312435.2|ensembl:ENSP00000387859.2|ensembl:ENSP00000388833.2|ensembl:ENSP00000401382.3|ensembl:ENSP00000401805.2|ensembl:ENSP00000405859.2|ensembl:ENSP00000410145.3|ensembl:ENSP00000412067.2|ensembl:ENSP00000415321.4|ensembl:ENSP00000501140.1|ensembl:ENSP00000501165.2|ensembl:ENSP00000513216.1|ensembl:ENSP00000513217.1|ensembl:ENSP00000513218.1	intact:EBI-2796292	psi-mi:dag1_human(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym)	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807420|imex:IM-13779-1143	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-40928N|efo:""Orphanet:280333""|efo:""Orphanet:370997""|efo:""Orphanet:899""|ensembl:ENSG00000173402.13(gene)|ensembl:ENST00000308775.7(transcript)|ensembl:ENST00000418588.6(transcript)|ensembl:ENST00000421560.6(transcript)|ensembl:ENST00000428779.7(transcript)|ensembl:ENST00000430636.2(transcript)|ensembl:ENST00000431960.6(transcript)|ensembl:ENST00000435508.8(transcript)|ensembl:ENST00000452060.7(transcript)|ensembl:ENST00000452317.6(transcript)|ensembl:ENST00000466701.2(transcript)|ensembl:ENST00000469139.2(transcript)|ensembl:ENST00000496474.2(transcript)|ensembl:ENST00000673708.1(transcript)|ensembl:ENST00000697271.1(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0003779""(actin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0007411""(axon guidance)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010470""(regulation of gastrulation)|go:""GO:0010717""(regulation of epithelial to mesenchymal transition)|go:""GO:0014850""(response to muscle activity)|go:""GO:0014894""(response to denervation involved in regulation of muscle adaptation)|go:""GO:0015031""(protein transport)|go:""GO:0015631""(tubulin binding)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016011""(dystroglycan complex)|go:""GO:0016020""(membrane)|go:""GO:0016203""(muscle attachment)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016340""(calcium-dependent cell-matrix adhesion)|go:""GO:0016476""(regulation of embryonic cell shape)|go:""GO:0017166""(vinculin binding)|go:""GO:0021675""(nerve development)|go:""GO:0021682""(nerve maturation)|go:""GO:0022011""(myelination in peripheral nervous system)|go:""GO:0030027""(lamellipodium)|go:""GO:0030175""(filopodium)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031103""(axon regeneration)|go:""GO:0031643""(positive regulation of myelination)|go:""GO:0033268""(node of Ranvier)|go:""GO:0034399""(nuclear periphery)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042383""(sarcolemma)|go:""GO:0043034""(costamere)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043236""(laminin binding)|go:""GO:0043237""(laminin-1 binding)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0050807""(regulation of synapse organization)|go:""GO:0051393""(alpha-actinin binding)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060055""(angiogenesis involved in wound healing)|go:""GO:0060441""(epithelial tube branching involved in lung morphogenesis)|go:""GO:0060445""(branching involved in salivary gland morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070938""(contractile ring)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071397""(cellular response to cholesterol)|go:""GO:0071679""(commissural neuron axon guidance)|go:""GO:0071711""(basement membrane organization)|go:""GO:0098684""(photoreceptor ribbon synapse)|go:""GO:0098696""(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:0098942""(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:1904261""(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015919(Cadherin-like)|interpro:IPR027468|interpro:IPR030398|interpro:IPR041631|mint:Q14118|rcsb pdb:1EG4|rcsb pdb:2MK7|rcsb pdb:5GGP|rcsb pdb:5LLK|rcsb pdb:6JJY|rcsb pdb:7E9K|rcsb pdb:7E9L|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-5083628|reactome:R-HSA-5083629|reactome:R-HSA-5083633|reactome:R-HSA-5173105|reactome:R-HSA-9010553|reactome:R-HSA-9619665|refseq:NP_001159400.2|refseq:NP_001171105.1|refseq:NP_001171106.1|refseq:NP_001171107.1|refseq:NP_001171108.1|refseq:NP_001171109.1|refseq:NP_001171110.1|refseq:NP_001171111.1|refseq:NP_001171112.1|refseq:NP_001171113.1|refseq:NP_001171114.1|refseq:NP_001171115.1|refseq:NP_004384.4|panther:PTHR21559(orthology-group)"	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:q+98wmc5ueyzkpOCrold06eukRg9606	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	intact-crc:9D489CF3DF541D84|rigid:wSfJV4sA9+eEaJTdfEFVj/UZG/4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF37	uniprotkb:P01034	intact:EBI-2798724	intact:EBI-948622|uniprotkb:Q6FGW9|uniprotkb:B2R5J9|uniprotkb:D3DW42|ensembl:ENSP00000366124.3|ensembl:ENSP00000381446.1|ensembl:ENSP00000381448.1	psi-mi:syp_fratt(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1412(locus name)	psi-mi:cytc_human(display_long)|uniprotkb:Cystatin-3(gene name synonym)|uniprotkb:Neuroendocrine basic polypeptide(gene name synonym)|uniprotkb:Gamma-trace(gene name synonym)|uniprotkb:Post-gamma-globulin(gene name synonym)|uniprotkb:CST3(gene name)|psi-mi:CST3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807459|imex:IM-13779-1147	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044140|refseq:YP_170355.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|interpro:IPR033730|refseq:WP_003022224.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR045864|interpro:IPR050062"	"efo:""Orphanet:100008""|ensembl:ENSG00000101439.9(gene)|ensembl:ENST00000376925.8(transcript)|ensembl:ENST00000398409.1(transcript)|ensembl:ENST00000398411.5(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0002020""(protease binding)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0010466""(negative regulation of peptidase activity)|go:""GO:0010711""(negative regulation of collagen catabolic process)|go:""GO:0010716""(negative regulation of extracellular matrix disassembly)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0031982""(vesicle)|go:""GO:0034103""(regulation of tissue remodeling)|go:""GO:0042802""(identical protein binding)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0060311""(negative regulation of elastin catabolic process)|go:""GO:0060313""(negative regulation of blood vessel remodeling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|interpro:IPR046350|mint:P01034|rcsb pdb:1G96|rcsb pdb:1R4C|rcsb pdb:1TIJ|rcsb pdb:3GAX|rcsb pdb:3NX0|rcsb pdb:3PS8|rcsb pdb:3QRD|rcsb pdb:3S67|rcsb pdb:3SVA|rcsb pdb:6ROA|rcsb pdb:6RPV|reactome:R-HSA-381426|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-977225|refseq:NP_000090.1|refseq:NP_001275543.1|panther:PTHR46186(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6/QkU5JRWJEBZMwaR9J83no0ffk177416	rogid:UJT8nc0DeqGBXeRiy8RnrB1tKGw9606	intact-crc:C4BA76B3CB252516|rigid:QdX+aLKmWp/5vTvwoNghd8QBj/k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99418	uniprotkb:Q5NGY9	intact:EBI-448974|ensembl:ENSP00000493357.1|intact:EBI-1760516|uniprotkb:Q8IXY9|uniprotkb:Q92958|intact:EBI-1965579|uniprotkb:A8K8P0	intact:EBI-2807476	psi-mi:cyh2_human(display_long)|uniprotkb:PH, SEC7 and coiled-coil domain-containing protein 2(gene name synonym)|uniprotkb:ARF nucleotide-binding site opener(gene name synonym)|uniprotkb:ARF exchange factor(gene name synonym)|uniprotkb:CYTH2(gene name)|psi-mi:CYTH2(display_short)|uniprotkb:ARNO(gene name synonym)|uniprotkb:PSCD2L(gene name synonym)|uniprotkb:PSCD2(gene name synonym)	psi-mi:hslu_fratt(display_long)|uniprotkb:hslU(gene name)|psi-mi:hslU(display_short)|uniprotkb:Unfoldase HslU(gene name synonym)|uniprotkb:FTT_0687c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807473|imex:IM-13779-1148	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105443.17(gene)|ensembl:ENST00000641098.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006897""(endocytosis)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030426""(growth cone)|go:""GO:0032012""(regulation of ARF protein signal transduction)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|mint:Q99418|rcsb pdb:1PBV|rcsb pdb:1R8M|rcsb pdb:1R8Q|rcsb pdb:1R8S|rcsb pdb:1S9D|rcsb pdb:4JMI|rcsb pdb:4JMO|rcsb pdb:4JWL|rcsb pdb:4JXH|rcsb pdb:4L5M|rcsb pdb:4Z21|reactome:R-HSA-6811438|panther:PTHR10663(orthology-group)|refseq:NP_004219.3|refseq:NP_059431.1|dip:DIP-31598N"	"interpro:IPR050052|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR004491(Heat shock protein HslU)|refseq:YP_169703.1|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0008233""(peptidase activity)|go:""GO:0009376""(HslUV protease complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043335""(protein unfolding)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|refseq:WP_003015770.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/28	rogid:wGF6f2/B1HkGHOB/juI9LS1N/ww9606	rogid:GP8B/X0zPdfNxpWahkJei03igv4177416	intact-crc:93575B0C902CA10B|rigid:Rfqsfk5yWWmLR5YaaoHPrvGAAiM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF53	uniprotkb:O00622	intact:EBI-2797592|uniprotkb:A0A0G2RMJ2	intact:EBI-1237454|uniprotkb:O14934|uniprotkb:O43775|uniprotkb:Q9BZL7|ensembl:ENSP00000398736.2	psi-mi:q5nf53_fratt(display_long)|uniprotkb:recB(gene name)|psi-mi:recB(display_short)|uniprotkb:Exonuclease V subunit RecB(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecB(gene name synonym)|uniprotkb:FTT_1394c(locus name)|uniprotkb:DNA 3'-5' helicase subunit RecB(gene name synonym)	psi-mi:ccn1_human(display_long)|uniprotkb:CCN1(gene name)|psi-mi:CCN1(display_short)|uniprotkb:CYR61(gene name synonym)|uniprotkb:Cellular communication network factor 1(gene name synonym)|uniprotkb:Cysteine-rich angiogenic inducer 61(gene name synonym)|uniprotkb:GIG1(gene name synonym)|uniprotkb:IGFBP10(gene name synonym)|uniprotkb:Insulin-like growth factor-binding protein 10(gene name synonym)|uniprotkb:Protein CYR61(gene name synonym)|uniprotkb:Protein GIG1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807466|imex:IM-13779-1146	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000287""(magnesium ion binding)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR004586(Exodeoxyribonuclease V, beta subunit)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|refseq:YP_170339.1|interpro:IPR027417|refseq:WP_003022196.1"	"refseq:NP_001545.2|ensembl:ENSG00000142871.18(gene)|ensembl:ENST00000451137.7(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002041""(intussusceptive angiogenesis)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0003278""(apoptotic process involved in heart morphogenesis)|go:""GO:0003281""(ventricular septum development)|go:""GO:0005178""(integrin binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006935""(chemotaxis)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0008201""(heparin binding)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0019838""(growth factor binding)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030501""(positive regulation of bone mineralization)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0060413""(atrial septum morphogenesis)|go:""GO:0060591""(chondroblast differentiation)|go:""GO:0060710""(chorio-allantoic fusion)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0061036""(positive regulation of cartilage development)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:2000304""(positive regulation of ceramide biosynthetic process)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR006208(Cystine knot)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012395(IGFBP-related, CNN)|interpro:IPR017891|interpro:IPR036383|interpro:IPR043973|interpro:IPR050941|mint:O00622|rcsb pdb:4D0Z|rcsb pdb:4D11|reactome:R-HSA-381426|reactome:R-HSA-8957275|panther:PTHR11348(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ii9dJldcaJ9ed2JkD66pMgtmBlQ177416	rogid:zjqBcViT2Kyh+41SJeOu/rcJqSk9606	intact-crc:D0E78B1085164AED|rigid:ADIXVSgP4DyQGgwdJnBfbys/QC0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O76096	uniprotkb:Q5NF74	intact:EBI-2807448|uniprotkb:Q6FH95|uniprotkb:Q9UED4|uniprotkb:Q7Z4J8|ensembl:ENSP00000420384.1	intact:EBI-2796785|uniprotkb:A0A0G2RND4	psi-mi:cytf_human(display_long)|uniprotkb:CST7(gene name)|psi-mi:CST7(display_short)|uniprotkb:Cystatin-7(gene name synonym)|uniprotkb:Cystatin-like metastasis-associated protein(gene name synonym)|uniprotkb:Leukocystatin(gene name synonym)	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807445|imex:IM-13779-1145	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003641.3|ensembl:ENSG00000077984.6(gene)|ensembl:ENST00000480798.2(transcript)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006955""(immune response)|go:""GO:0010466""(negative regulation of peptidase activity)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031643""(positive regulation of myelination)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:1903979""(negative regulation of microglial cell activation)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR042886|interpro:IPR046350|mint:O76096|rcsb pdb:2CH9|panther:PTHR47141(orthology-group)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xNa8wSYNqctn1+5GA1bFyG9kk+k9606	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	intact-crc:5EF618C4C180DA27|rigid:UPdYu6CfCEMt2C6lzHAo86WSVZQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGZ7	intact:EBI-2807508	intact:EBI-2801271|uniprotkb:A0A0G2RN55	-	psi-mi:q5ngz7_fratt(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:FTT_0679c(locus name)	psi-mi:cv027_human(display_short)|psi-mi:EBI-2807508(display_long)|uniprotkb:C22orf27(gene name)|psi-mi:C22orf27(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807505|imex:IM-13779-1152	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|refseq:YP_169695.1|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0043023""(ribosomal large subunit binding)|interpro:IPR041706|interpro:IPR004095(TGS)|refseq:WP_003020468.1"	uniprotkb:Q8N0Y4(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tfY1+moC9oziAj7eZ4ePmeICDRQ177416	rogid:bmfxkrhM2zZ5SaxvWZ+VDcBlpVU9606	intact-crc:F7D14E5FC64DCE1A|rigid:LoWr5YkgoHhgt6OZRJnNuODuV8o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFY5	uniprotkb:Q9P013	intact:EBI-2799103|uniprotkb:A0A0G2RM96	intact:EBI-2371709|uniprotkb:B2RC17|uniprotkb:Q05BV9|uniprotkb:Q05DM1|uniprotkb:Q9UI29|ensembl:ENSP00000475615.2	psi-mi:q5nfy5_fratt(display_long)|uniprotkb:FTT_1078c(locus name)	psi-mi:cwc15_human(display_long)|uniprotkb:CWC15(gene name)|psi-mi:CWC15(display_short)|uniprotkb:C11orf5(gene name synonym)|uniprotkb:AD-002(orf name)|uniprotkb:HSPC148(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807498|imex:IM-13779-1150	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003021212.1	"refseq:XP_011541170.1|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|ensembl:ENSG00000150316.12(gene)|ensembl:ENST00000279839.8(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000974""(Prp19 complex)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0016607""(nuclear speck)|go:""GO:0045292""(mRNA cis splicing, via spliceosome)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|interpro:IPR006973(Cwf15/Cwc15 cell cycle control protein)|mint:Q9P013|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8RO2|rcsb pdb:9FMD|reactome:R-HSA-72163|refseq:NP_057487.2|refseq:XP_016873405.1|panther:PTHR12718(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZCh5UU3BrwGnp/Qxno/CBNEc368177416	rogid:Sq0ehGSKIEKx1X9xv4Nx0ZiqXhk9606	intact-crc:94835F5B169F2F19|rigid:oKNn+JzDbVloMooGja3apjWzb/0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43927	uniprotkb:Q5NEJ4	intact:EBI-719170|ensembl:ENSP00000286758.4|ensembl:ENSP00000507688.1	intact:EBI-2799894|uniprotkb:A0A0G2RQA6	psi-mi:cxl13_human(display_long)|uniprotkb:Small-inducible cytokine B13(gene name synonym)|uniprotkb:B lymphocyte chemoattractant(gene name synonym)|uniprotkb:CXC chemokine BLC(gene name synonym)|uniprotkb:B cell-attracting chemokine 1(gene name synonym)|uniprotkb:CXCL13(gene name)|psi-mi:CXCL13(display_short)|uniprotkb:BCA1(gene name synonym)|uniprotkb:BLC(gene name synonym)|uniprotkb:SCYB13(gene name synonym)|uniprotkb:Angie(gene name synonym)	psi-mi:q5nej4_fratt(display_long)|uniprotkb:ftsK(gene name)|psi-mi:ftsK(display_short)|uniprotkb:FTT_1635(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807491|imex:IM-13779-1151	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006410.1|ensembl:ENSG00000156234.8(gene)|ensembl:ENST00000286758.4(transcript)|ensembl:ENST00000682537.1(transcript)|go:""GO:0002467""(germinal center formation)|go:""GO:0002518""(lymphocyte chemotaxis across high endothelial venule)|go:""GO:0002544""(chronic inflammatory response)|go:""GO:0002920""(regulation of humoral immune response)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008009""(chemokine activity)|go:""GO:0008201""(heparin binding)|go:""GO:0010820""(positive regulation of T cell chemotaxis)|go:""GO:0017134""(fibroblast growth factor binding)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0031724""(CXCR5 chemokine receptor binding)|go:""GO:0031735""(CCR10 chemokine receptor binding)|go:""GO:0033625""(positive regulation of integrin activation)|go:""GO:0033634""(positive regulation of cell-cell adhesion mediated by integrin)|go:""GO:0035754""(B cell chemotaxis)|go:""GO:0035768""(endothelial cell chemotaxis to fibroblast growth factor)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045236""(CXCR chemokine receptor binding)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048248""(CXCR3 chemokine receptor binding)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:2000545""(negative regulation of endothelial cell chemotaxis to fibroblast growth factor)|interpro:IPR001089(Small chemokine, C-X-C)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR018048|interpro:IPR033899|interpro:IPR036048|interpro:IPR039809|mint:O43927|rcsb pdb:5CBA|rcsb pdb:5CBE|rcsb pdb:6VGJ|rcsb pdb:7JNY|reactome:R-HSA-380108|reactome:R-HSA-418594|refseq:XP_006714126.1|dip:DIP-5914N|panther:PTHR12015(orthology-group)"	"interpro:IPR002543(Cell divisionFtsK/SpoIIIE)|interpro:IPR018541|refseq:YP_170548.1|interpro:IPR027417|interpro:IPR025199|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007059""(chromosome segregation)|go:""GO:0051301""(cell division)|refseq:WP_003022567.1|interpro:IPR036388|interpro:IPR036390|interpro:IPR041027|interpro:IPR050206"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5/65nY3r+t/6Br3fQLOX+1JENJQ9606	rogid:MHG0tEU4NHSPB6cp/UeAYw2sOLQ177416	intact-crc:662838005023DDDD|rigid:/nhhJss69ZdoQ7Kb7N/RfkWRy84	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7L576	uniprotkb:Q5NFJ2	intact:EBI-1048143|uniprotkb:Q14467|uniprotkb:Q5IED0|uniprotkb:Q6ZSX1|uniprotkb:Q9BSD9|uniprotkb:Q9BVC7|uniprotkb:A8K6D9|ensembl:ENSP00000478779.1|ensembl:ENSP00000481038.1|ensembl:ENSP00000499947.1|ensembl:ENSP00000500331.1	intact:EBI-2801973|uniprotkb:A0A0G2RP12	psi-mi:cyfp1_human(display_long)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)|uniprotkb:p140sra-1(gene name synonym)|uniprotkb:CYFIP1(gene name)|psi-mi:CYFIP1(display_short)|uniprotkb:KIAA0068(gene name synonym)	psi-mi:q5nfj2_fratt(display_long)|uniprotkb:FTT_1242(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807484|imex:IM-13779-1149	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001028200.1|refseq:NP_055423.1|refseq:NP_001274739.1|ensembl:ENSG00000273749.5(gene)|ensembl:ENSG00000288461.1(gene)|ensembl:ENST00000610365.4(transcript)|ensembl:ENST00000617928.5(transcript)|ensembl:ENST00000671714.1(transcript)|ensembl:ENST00000672091.1(transcript)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001726""(ruffle)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006417""(regulation of translation)|go:""GO:0007411""(axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0030027""(lamellipodium)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030371""(translation repressor activity)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0031209""(SCAR complex)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031529""(ruffle organization)|go:""GO:0031641""(regulation of myelination)|go:""GO:0032433""(filopodium tip)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043195""(terminal bouton)|go:""GO:0043197""(dendritic spine)|go:""GO:0044294""(dendritic growth cone)|go:""GO:0044295""(axonal growth cone)|go:""GO:0045202""(synapse)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048675""(axon extension)|go:""GO:0050890""(cognition)|go:""GO:0051015""(actin filament binding)|go:""GO:0051388""(positive regulation of neurotrophin TRK receptor signaling pathway)|go:""GO:0051602""(response to electrical stimulus)|go:""GO:0060076""(excitatory synapse)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090724""(central region of growth cone)|go:""GO:0090725""(peripheral region of growth cone)|go:""GO:0097484""(dendrite extension)|go:""GO:0099563""(modification of synaptic structure)|go:""GO:0099578""(regulation of translation at postsynapse, modulating synaptic transmission)|go:""GO:1900006""(positive regulation of dendrite development)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1903422""(negative regulation of synaptic vesicle recycling)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:2000601""(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7L576|rcsb pdb:3P8C|rcsb pdb:4N78|rcsb pdb:7USC|rcsb pdb:7USD|rcsb pdb:7USE|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001311049.1|refseq:NP_001311052.1|dip:DIP-38873N|panther:PTHR12195(orthology-group)"	refseq:YP_170200.1|refseq:WP_003021546.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:cEF+RA9JRXz8Mbsl/s89Up2ONRc9606	rogid:2TebkELetBwT7JBLunOX5Gxqzdk177416	intact-crc:5CB14EA51FEF1415|rigid:45DS1IHuP+/EBCyYL4dMVj7X0NA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6XXX2	uniprotkb:Q5NEC0	intact:EBI-2807537	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:cu024_human(display_long)|uniprotkb:NCRNA00114(gene name synonym)|uniprotkb:LINC00114(gene name)|psi-mi:LINC00114(display_short)|uniprotkb:C21orf24(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807541|imex:IM-13779-1156	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oAdedjlPGSx8tuCWC8i453jAjEs9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:6394377FDAC22650|rigid:Smw/Zq9AwHKdbN6RO3iFd1f8zIs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGN2	uniprotkb:Q13617	intact:EBI-2803463|uniprotkb:A0A0G2RMU1	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363880.1|ensembl:ENSP00000363881.3|ensembl:ENSP00000363883.3|ensembl:ENSP00000501215.1|ensembl:ENSP00000508908.1|ensembl:ENSP00000510691.1	psi-mi:q5ngn2_fratt(display_long)|uniprotkb:ans(gene name)|psi-mi:ans(display_short)|uniprotkb:FTT_0803(locus name)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807523|imex:IM-13779-1155	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000246(Peptidase T2, asparaginase 2)|refseq:YP_169810.1|go:""GO:0004067""(asparaginase activity)|interpro:IPR029055|refseq:WP_003020718.1"	"refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|ensembl:ENSG00000108094.17(gene)|ensembl:ENST00000374748.5(transcript)|ensembl:ENST00000374749.8(transcript)|ensembl:ENST00000374751.7(transcript)|ensembl:ENST00000673636.2(transcript)|ensembl:ENST00000690393.1(transcript)|ensembl:ENST00000691974.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019005""(SCF ubiquitin ligase complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030891""(VCB complex)|go:""GO:0031146""(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:0160072""(ubiquitin ligase complex scaffold activity)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|interpro:IPR045093|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:7PLO|rcsb pdb:8IJ1|rcsb pdb:8JAL|rcsb pdb:8JAQ|rcsb pdb:8JAR|rcsb pdb:8JAS|rcsb pdb:8JAU|rcsb pdb:8JAV|rcsb pdb:8JE1|rcsb pdb:8JE2|rcsb pdb:8PQL|rcsb pdb:8Q7R|rcsb pdb:8QU8|rcsb pdb:8R5H|rcsb pdb:8RWZ|rcsb pdb:8RX0|rcsb pdb:8WDK|rcsb pdb:8WQA|rcsb pdb:8WQB|rcsb pdb:8WQC|rcsb pdb:8WQE|rcsb pdb:8WQF|rcsb pdb:8WQG|rcsb pdb:8WQH|reactome:R-HSA-1234176|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-983168|dip:DIP-31612N|panther:PTHR11932(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:Seck/e2N8Okq24qR9dX3A4maVVU177416	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	intact-crc:CCB750EAE862636E|rigid:8xVaQxrk5fLjj+F7m2qpG9LWxiE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI89	uniprotkb:Q13616	intact:EBI-2796250	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804.3|ensembl:ENSP00000387160.1|ensembl:ENSP00000473318.1|ensembl:ENSP00000499255.1|ensembl:ENSP00000499277.1|ensembl:ENSP00000499398.1	psi-mi:q5ni89_fratt(display_long)|uniprotkb:lysS(gene name synonym)|uniprotkb:lysU(gene name)|psi-mi:lysU(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0192(locus name)	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807530|imex:IM-13779-1154	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|interpro:IPR044136|refseq:YP_169253.1|interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR045864"	"refseq:NP_003583.2|refseq:XP_005250117.1|ensembl:ENSG00000055130.18(gene)|ensembl:ENST00000325222.9(transcript)|ensembl:ENST00000409469.5(transcript)|ensembl:ENST00000602748.5(transcript)|ensembl:ENST00000662716.1(transcript)|ensembl:ENST00000663044.1(transcript)|ensembl:ENST00000665936.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019005""(SCF ubiquitin ligase complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031146""(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0031461""(cullin-RING ubiquitin ligase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0160072""(ubiquitin ligase complex scaffold activity)|go:""GO:1990452""(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|interpro:IPR045093|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|rcsb pdb:7Z8R|rcsb pdb:7Z8T|rcsb pdb:7Z8V|rcsb pdb:7ZBW|rcsb pdb:7ZBZ|rcsb pdb:8CAF|rcsb pdb:8CDJ|rcsb pdb:8CDK|rcsb pdb:8OR0|rcsb pdb:8OR2|rcsb pdb:8OR3|rcsb pdb:8OR4|rcsb pdb:9JKB|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-9725371|reactome:R-HSA-9762114|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|dip:DIP-17013N|panther:PTHR11932(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:4e6LdrlEB4PMi+b0yLmkVagonC4177416	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	intact-crc:70609B1BB1AD8FDC|rigid:mLVrq5K4fahmbVQnKwaGG2zP7og	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEB6	uniprotkb:O60888	intact:EBI-2797029|uniprotkb:A0A0G2RNW9	intact:EBI-1051556|uniprotkb:A2AB26|uniprotkb:A2BEL4|uniprotkb:Q3B784|uniprotkb:Q5JXM9|uniprotkb:Q5SU05|uniprotkb:Q9NYQ9|ensembl:ENSP00000400114.2|ensembl:ENSP00000417544.1	psi-mi:q5neb6_fratt(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:FTT_1724c(locus name)	psi-mi:cuta_human(display_long)|uniprotkb:Brain acetylcholinesterase putative membrane anchor(gene name synonym)|uniprotkb:Acetylcholinesterase-associated protein(gene name synonym)|uniprotkb:CUTA(gene name)|psi-mi:CUTA(display_short)|uniprotkb:ACHAP(gene name synonym)|uniprotkb:C6orf82(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807516|imex:IM-13779-1153	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:1990281""(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|refseq:YP_170626.1|refseq:WP_003022695.1|interpro:IPR051906"	"refseq:NP_001014433.1|refseq:NP_001014837.1|refseq:NP_001014838.1|refseq:NP_001014840.1|refseq:NP_057005.1|ensembl:ENSG00000112514.18(gene)|ensembl:ENSG00000226492.7(gene)|ensembl:ENST00000440930.6(transcript)|ensembl:ENST00000488034.6(transcript)|go:""GO:0005507""(copper ion binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0008104""(protein localization)|go:""GO:0010038""(response to metal ion)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR004323(Divalent ion tolerance protein, CutA1)|interpro:IPR011322(Nitrogen regulatory PII-like, alpha/beta)|interpro:IPR015867(Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal)|rcsb pdb:1XK8|rcsb pdb:2ZFH|panther:PTHR23419(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rzu9m+ahxwjrbytyPusL6ALCJRw177416	rogid:wkpwCJMyS0gzcV9GHlhXAN5xVeI9606	intact-crc:296D7F271788AFF1|rigid:cEvGOxr+Cx0A/I6d80/cG/rzon8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y5B0	uniprotkb:Q5NF74	intact:EBI-2807555|uniprotkb:Q9Y6F5|uniprotkb:Q7Z644|uniprotkb:Q96BZ1|uniprotkb:A8MY97|ensembl:ENSP00000484525.2	intact:EBI-2796785|uniprotkb:A0A0G2RND4	psi-mi:ctdp1_human(display_long)|uniprotkb:CTDP1(gene name)|psi-mi:CTDP1(display_short)|uniprotkb:FCP1(gene name synonym)|uniprotkb:TFIIF-associating CTD phosphatase(gene name synonym)	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807562|imex:IM-13779-1160	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000060069.18(gene)|ensembl:ENST00000613122.5(transcript)|go:""GO:0000922""(spindle pole)|go:""GO:0001096""(TFIIF-class transcription factor complex binding)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008420""(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:""GO:0010458""(exit from mitosis)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0030496""(midbody)|go:""GO:0030957""(Tat protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0051233""(spindle midzone)|go:""GO:0051301""(cell division)|go:""GO:0061052""(negative regulation of cell growth involved in cardiac muscle cell development)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR001357(BRCT)|interpro:IPR004274(NLI interacting factor)|interpro:IPR011947(FCP1-like phosphatase, phosphatase domain)|interpro:IPR015388(FCP1-like phosphatase, C-terminal)|interpro:IPR023214|interpro:IPR036412|interpro:IPR036420|interpro:IPR039189|mint:Q9Y5B0|rcsb pdb:1J2X|rcsb pdb:1ONV|rcsb pdb:2K7L|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_001189433.1|refseq:NP_004706.3|refseq:NP_430255.2|dip:DIP-41788N|efo:""Orphanet:48431""|panther:PTHR23081(orthology-group)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LEqMeYJjhIWOx3RZtX3ljR5IZS49606	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	intact-crc:78FFAE5FE0D6340E|rigid:bUSz/iufsxy2iZ5/QXc0bybBvx8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF60	uniprotkb:O94964	intact:EBI-2799293	intact:EBI-2433678|uniprotkb:A6NK10|uniprotkb:Q14DB2|uniprotkb:Q5JW51|uniprotkb:Q6ZTG8|ensembl:ENSP00000237536.4	"psi-mi:dnlj_fratt(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:""Polydeoxyribonucleotide synthase [NAD(+)]""(gene name synonym)|uniprotkb:FTT_1387c(locus name)"	psi-mi:mtcl2_human(display_long)|uniprotkb:MTCL2(gene name)|psi-mi:MTCL2(display_short)|uniprotkb:C20orf117(gene name synonym)|uniprotkb:KIAA0889(gene name synonym)|uniprotkb:SOGA(gene name synonym)|uniprotkb:SOGA family member 1(gene name synonym)|uniprotkb:SOGA1(gene name synonym)|uniprotkb:Suppressor of glucose by autophagy(gene name synonym)|uniprotkb:Suppressor of glucose, autophagy-associated protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807569|imex:IM-13779-1158	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_170332.1|interpro:IPR001357(BRCT)|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR004149(Zinc-finger, NAD-dependent DNA ligase C4-type)|go:""GO:0003677""(DNA binding)|go:""GO:0003911""(""DNA ligase (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006288""(obsolete base-excision repair, DNA ligation)|go:""GO:0046872""(metal ion binding)|refseq:WP_003024021.1|interpro:IPR033136|interpro:IPR036420|interpro:IPR041663"	"refseq:NP_542194.2|refseq:NP_954650.2|ensembl:ENSG00000149639.15(gene)|ensembl:ENST00000237536.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005874""(microtubule)|go:""GO:0007059""(chromosome segregation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0030496""(midbody)|go:""GO:0045721""(negative regulation of gluconeogenesis)|go:""GO:0051301""(cell division)|go:""GO:0070062""(extracellular exosome)|interpro:IPR027881|interpro:IPR027882|interpro:IPR049885|mint:O94964|panther:PTHR15742(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rHqrcgB9uMgr4visMI6R3FjEECc177416	rogid:Zb6cO9a65xcwpeE4mVoQ9mnqjNs9606	intact-crc:54CE2B487EC0DED1|rigid:QPEfdCoNTh1kVCS8yrjwJ+Kto50	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BY42	uniprotkb:Q5NEW4	intact:EBI-1045669|uniprotkb:Q9BYL7|uniprotkb:Q9HCV9|uniprotkb:Q9NX29|uniprotkb:Q9NZZ8|uniprotkb:Q9P002|uniprotkb:Q9UHW3|uniprotkb:E1P5Z9|ensembl:ENSP00000349906.6	intact:EBI-2804278|uniprotkb:A0A0G2RNG0	psi-mi:rtf2_human(display_long)|uniprotkb:RTF2(gene name)|psi-mi:RTF2(display_short)|uniprotkb:C20orf43(gene name synonym)|uniprotkb:RTFDC1(gene name synonym)|uniprotkb:Replication termination factor 2 domain-containing protein 1(gene name synonym)|uniprotkb:AD-007(orf name)|uniprotkb:CDA05(orf name)|uniprotkb:HSPC164(orf name)|uniprotkb:HSPC169(orf name)	psi-mi:q5new4_fratt(display_long)|uniprotkb:FTT_1493c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807576|imex:IM-13779-1161	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269964.1|refseq:NP_001269965.1|refseq:NP_001269966.1|refseq:NP_057491.2|ensembl:ENSG00000022277.13(gene)|ensembl:ENST00000357348.10(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005657""(replication fork)|go:""GO:0072711""(cellular response to hydroxyurea)|go:""GO:0097752""(regulation of DNA stability)|go:""GO:1902979""(mitotic DNA replication termination)|interpro:IPR006735(Protein of unknown function DUF602)|interpro:IPR027799|mint:Q9BY42|panther:PTHR12775(orthology-group)"	refseq:YP_170428.1|refseq:WP_003022358.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eh/6sc/MIM9QOLgd0NfZaezJ7ek9606	rogid:27huGXtUR7EE86YZGD/S43e1SDg177416	intact-crc:C2812B8FF1907714|rigid:gki0wgKUOD7P4lFpwJ9ls3fd+t4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35222	uniprotkb:Q5NEM9	intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|uniprotkb:A8K1L7|ensembl:ENSP00000344456.5|ensembl:ENSP00000379486.3|ensembl:ENSP00000379488.3|ensembl:ENSP00000385604.1|ensembl:ENSP00000387455.2|ensembl:ENSP00000401599.2|ensembl:ENSP00000409302.2|ensembl:ENSP00000412219.2|ensembl:ENSP00000493533.1|ensembl:ENSP00000493583.2|ensembl:ENSP00000493610.1|ensembl:ENSP00000494053.1|ensembl:ENSP00000494411.1|ensembl:ENSP00000494677.1|ensembl:ENSP00000494845.1|ensembl:ENSP00000494914.1|ensembl:ENSP00000495076.1|ensembl:ENSP00000495244.1|ensembl:ENSP00000495360.1|ensembl:ENSP00000495450.1|ensembl:ENSP00000495719.1|ensembl:ENSP00000495992.1|ensembl:ENSP00000496021.1|ensembl:ENSP00000496180.1|ensembl:ENSP00000496385.1|intact:EBI-491563	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807548|imex:IM-13779-1157	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168036.19(gene)|ensembl:ENST00000349496.11(transcript)|ensembl:ENST00000396183.7(transcript)|ensembl:ENST00000396185.8(transcript)|ensembl:ENST00000405570.6(transcript)|ensembl:ENST00000431914.6(transcript)|ensembl:ENST00000433400.6(transcript)|ensembl:ENST00000441708.2(transcript)|ensembl:ENST00000450969.6(transcript)|ensembl:ENST00000642248.1(transcript)|ensembl:ENST00000642315.1(transcript)|ensembl:ENST00000642426.1(transcript)|ensembl:ENST00000642992.1(transcript)|ensembl:ENST00000643031.1(transcript)|ensembl:ENST00000643297.1(transcript)|ensembl:ENST00000643541.1(transcript)|ensembl:ENST00000643977.1(transcript)|ensembl:ENST00000643992.1(transcript)|ensembl:ENST00000644867.1(transcript)|ensembl:ENST00000645210.1(transcript)|ensembl:ENST00000645320.1(transcript)|ensembl:ENST00000645982.1(transcript)|ensembl:ENST00000646369.1(transcript)|ensembl:ENST00000646725.1(transcript)|ensembl:ENST00000647390.1(transcript)|ensembl:ENST00000647413.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000578""(embryonic axis specification)|go:""GO:0000791""(euchromatin)|go:""GO:0000922""(spindle pole)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0001569""(branching involved in blood vessel morphogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001658""(branching involved in ureteric bud morphogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001708""(cell fate specification)|go:""GO:0001711""(endodermal cell fate commitment)|go:""GO:0001764""(neuron migration)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001840""(neural plate development)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0002053""(positive regulation of mesenchymal cell proliferation)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0002089""(lens morphogenesis in camera-type eye)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003266""(regulation of secondary heart field cardioblast proliferation)|go:""GO:0003338""(metanephros morphogenesis)|go:""GO:0003340""(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005916""(fascia adherens)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007398""(ectoderm development)|go:""GO:0007403""(glial cell fate determination)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0009950""(dorsal/ventral axis specification)|go:""GO:0009954""(proximal/distal pattern formation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010909""(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016342""(catenin complex)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0016600""(flotillin complex)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021819""(layer formation in cerebral cortex)|go:""GO:0021854""(hypothalamus development)|go:""GO:0022009""(central nervous system vasculogenesis)|go:""GO:0030018""(Z disc)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030539""(male genitalia development)|go:""GO:0030877""(beta-catenin destruction complex)|go:""GO:0030902""(hindbrain development)|go:""GO:0030997""(regulation of centriole-centriole cohesion)|go:""GO:0031016""(pancreas development)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031528""(microvillus membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031641""(regulation of myelination)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0032355""(response to estradiol)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034750""(Scrib-APC-beta-catenin complex)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0035112""(genitalia morphogenesis)|go:""GO:0035115""(embryonic forelimb morphogenesis)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035315""(hair cell differentiation)|go:""GO:0035995""(detection of muscle stretch)|go:""GO:0036023""(embryonic skeletal limb joint morphogenesis)|go:""GO:0036520""(astrocyte-dopaminergic neuron signaling)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0044338""(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:""GO:0045177""(apical part of cell)|go:""GO:0045202""(synapse)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045453""(bone resorption)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045603""(positive regulation of endothelial cell differentiation)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0045743""(positive regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045976""(negative regulation of mitotic cell cycle, embryonic)|go:""GO:0046332""(SMAD binding)|go:""GO:0048145""(regulation of fibroblast proliferation)|go:""GO:0048469""(cell maturation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0048538""(thymus development)|go:""GO:0048599""(oocyte development)|go:""GO:0048617""(embryonic foregut morphogenesis)|go:""GO:0048643""(positive regulation of skeletal muscle tissue development)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0048664""(neuron fate determination)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048715""(negative regulation of oligodendrocyte differentiation)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0050808""(synapse organization)|go:""GO:0051145""(smooth muscle cell differentiation)|go:""GO:0051450""(myoblast proliferation)|go:""GO:0051884""(regulation of timing of anagen)|go:""GO:0051963""(regulation of synapse assembly)|go:""GO:0060066""(oviduct development)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060440""(trachea formation)|go:""GO:0060441""(epithelial tube branching involved in lung morphogenesis)|go:""GO:0060484""(lung-associated mesenchyme development)|go:""GO:0060487""(lung epithelial cell differentiation)|go:""GO:0060492""(lung induction)|go:""GO:0060742""(epithelial cell differentiation involved in prostate gland development)|go:""GO:0060767""(epithelial cell proliferation involved in prostate gland development)|go:""GO:0060769""(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:0060789""(hair follicle placode formation)|go:""GO:0060856""(establishment of blood-brain barrier)|go:""GO:0060916""(mesenchymal cell proliferation involved in lung development)|go:""GO:0061047""(positive regulation of branching involved in lung morphogenesis)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0061198""(fungiform papilla formation)|go:""GO:0061549""(sympathetic ganglion development)|go:""GO:0061550""(cranial ganglion development)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070369""(beta-catenin-TCF7L2 complex)|go:""GO:0070411""(I-SMAD binding)|go:""GO:0070602""(regulation of centromeric sister chromatid cohesion)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0071944""(cell periphery)|go:""GO:0072033""(renal vesicle formation)|go:""GO:0072053""(renal inner medulla development)|go:""GO:0072054""(renal outer medulla development)|go:""GO:0072079""(nephron tubule formation)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0072182""(regulation of nephron tubule epithelial cell differentiation)|go:""GO:0072497""(mesenchymal stem cell differentiation)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0090279""(regulation of calcium ion import)|go:""GO:0090425""(acinar cell differentiation)|go:""GO:0097091""(synaptic vesicle clustering)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098831""(presynaptic active zone cytoplasmic component)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1901331""(positive regulation of odontoblast differentiation)|go:""GO:1903377""(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:""GO:1904888""(cranial skeletal system development)|go:""GO:1904948""(midbrain dopaminergic neuron differentiation)|go:""GO:1990138""(neuron projection extension)|go:""GO:1990226""(histone methyltransferase binding)|go:""GO:1990403""(embryonic brain development)|go:""GO:1990711""(beta-catenin-ICAT complex)|go:""GO:1990791""(dorsal root ganglion development)|go:""GO:1990907""(beta-catenin-TCF complex)|go:""GO:1990909""(Wnt signalosome)|go:""GO:1990963""(establishment of blood-retinal barrier)|go:""GO:2000008""(regulation of protein localization to cell surface)|go:""GO:2000017""(positive regulation of determination of dorsal identity)|go:""GO:2000288""(positive regulation of myoblast proliferation)|go:""GO:2000648""(positive regulation of stem cell proliferation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|rcsb pdb:7AR4|rcsb pdb:7UWI|rcsb pdb:7UWO|rcsb pdb:7ZRB|rcsb pdb:8EI9|rcsb pdb:8EIA|rcsb pdb:8EIB|rcsb pdb:8EIC|rcsb pdb:8RU3|rcsb pdb:8RU4|rcsb pdb:8VME|rcsb pdb:8VMF|rcsb pdb:8Y0G|rcsb pdb:8Y0P|rcsb pdb:8Y14|rcsb pdb:8Z0U|rcsb pdb:8Z10|rcsb pdb:8Z5J|rcsb pdb:8Z61|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|reactome:R-HSA-3134973|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|reactome:R-HSA-9733709|reactome:R-HSA-9754189|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9793380|reactome:R-HSA-9796292|reactome:R-HSA-9823730|reactome:R-HSA-9824272|reactome:R-HSA-9824585|reactome:R-HSA-9825892|reactome:R-HSA-9830364|reactome:R-HSA-9833576|reactome:R-HSA-9834899|reactome:R-HSA-9856530|reactome:R-HSA-9856649|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1|efo:""Orphanet:1501""|efo:""Orphanet:210159""|efo:""Orphanet:33402""|efo:""Orphanet:404473""|efo:""Orphanet:54595""|efo:""Orphanet:569248""|efo:""Orphanet:873""|efo:""Orphanet:891""|efo:""Orphanet:91414""|dip:DIP-122N|panther:PTHR45976(orthology-group)|ensembl:ENSP00000344456.5|ensembl:ENSP00000379486.3|ensembl:ENSP00000379488.3|ensembl:ENSP00000385604.1|ensembl:ENSP00000412219.2|ensembl:ENSP00000387455.2|ensembl:ENSP00000401599.2|ensembl:ENSP00000409302.2|ensembl:ENSP00000495244.1|ensembl:ENSP00000495076.1|ensembl:ENSP00000495719.1|ensembl:ENSP00000496385.1|ensembl:ENSP00000495450.1|ensembl:ENSP00000494677.1|ensembl:ENSP00000494411.1|ensembl:ENSP00000494053.1|ensembl:ENSP00000493610.1|ensembl:ENSP00000495992.1|ensembl:ENSP00000496180.1|ensembl:ENSP00000495360.1|ensembl:ENSP00000494845.1|ensembl:ENSP00000494914.1|ensembl:ENSP00000496021.1|ensembl:ENSP00000493533.1|ensembl:ENSP00000493583.2"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:3F173B8F3B47F5B7|rigid:unyRULhbm/vkzlRLo6fCd4VycPw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P67870	uniprotkb:Q5NID1	intact:EBI-348169|uniprotkb:P07312|uniprotkb:P13862|ensembl:ENSP00000365025.2|ensembl:ENSP00000365026.2|ensembl:ENSP00000365042.3|ensembl:ENSP00000372919.2|ensembl:ENSP00000372925.4|ensembl:ENSP00000382980.1|ensembl:ENSP00000390900.2|ensembl:ENSP00000391038.1|ensembl:ENSP00000393756.1|ensembl:ENSP00000394855.1|ensembl:ENSP00000395275.1|ensembl:ENSP00000400188.2|ensembl:ENSP00000407018.2|ensembl:ENSP00000407379.1|ensembl:ENSP00000409510.1|ensembl:ENSP00000410802.1|ensembl:ENSP00000411322.1|ensembl:ENSP00000412520.1|ensembl:ENSP00000413469.1|ensembl:ENSP00000415237.2|ensembl:ENSP00000415303.2|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9	intact:EBI-2796238	psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym)	psi-mi:rpoc_fratt(display_long)|uniprotkb:RNA polymerase subunit beta'(gene name synonym)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:FTT_0145(locus name)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807583|imex:IM-13779-1159	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204435.15(gene)|ensembl:ENSG00000206406.9(gene)|ensembl:ENSG00000224398.7(gene)|ensembl:ENSG00000224774.7(gene)|ensembl:ENSG00000228875.8(gene)|ensembl:ENSG00000230700.11(gene)|ensembl:ENSG00000232960.12(gene)|ensembl:ENST00000375865.6(transcript)|ensembl:ENST00000375866.2(transcript)|ensembl:ENST00000375882.7(transcript)|ensembl:ENST00000383427.6(transcript)|ensembl:ENST00000383433.8(transcript)|ensembl:ENST00000400110.5(transcript)|ensembl:ENST00000412802.5(transcript)|ensembl:ENST00000418230.5(transcript)|ensembl:ENST00000422567.6(transcript)|ensembl:ENST00000429633.5(transcript)|ensembl:ENST00000431476.5(transcript)|ensembl:ENST00000436169.5(transcript)|ensembl:ENST00000443673.6(transcript)|ensembl:ENST00000448596.1(transcript)|ensembl:ENST00000451917.6(transcript)|ensembl:ENST00000452985.6(transcript)|ensembl:ENST00000453234.5(transcript)|ensembl:ENST00000454382.6(transcript)|ensembl:ENST00000454511.5(transcript)|ensembl:ENST00000455161.1(transcript)|ensembl:ENST00000458330.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005956""(protein kinase CK2 complex)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016605""(PML body)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032927""(positive regulation of activin receptor signaling pathway)|go:""GO:0033211""(adiponectin-activated signaling pathway)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051101""(regulation of DNA binding)|go:""GO:0060391""(positive regulation of SMAD protein signal transduction)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0075342""(symbiont-mediated disruption of host cell PML body)|go:""GO:1903901""(negative regulation of viral life cycle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:6Q38|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|reactome:R-HSA-9755511|reactome:R-HSA-9828806|refseq:NP_001269314.1|refseq:NP_001311.3|dip:DIP-131N|panther:PTHR11740(orthology-group)|efo:""Orphanet:178469"""	"go:""GO:0000287""(magnesium ion binding)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0008270""(zinc ion binding)|interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|refseq:YP_169211.1|refseq:WP_003019910.1|interpro:IPR038120|interpro:IPR044893|interpro:IPR045867|interpro:IPR042102"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606	rogid:nCrO43u1Xg+RCZk3AEfSW6oQCNA177416	intact-crc:EC745702C430D527|rigid:dn/0wVS8RnWDiRPw142sqlizHrk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q70SY1	uniprotkb:Q5NFY4	intact:EBI-1640632|uniprotkb:Q6P454|uniprotkb:Q6ZMR6|ensembl:ENSP00000329140.6	intact:EBI-2799645|uniprotkb:A0A0G2RQ80	psi-mi:cr3l2_human(display_long)|uniprotkb:CREB3L2(gene name)|psi-mi:CREB3L2(display_short)|uniprotkb:BBF2H7(gene name synonym)|uniprotkb:BBF2 human homolog on chromosome 7(gene name synonym)	psi-mi:q5nfy4_fratt(display_long)|uniprotkb:FTT_1079c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807615|imex:IM-13779-1163	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000182158.16(gene)|ensembl:ENST00000330387.11(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051216""(cartilage development)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR046347|reactome:R-HSA-8874211|refseq:NP_001240704.1|refseq:NP_919047.2|efo:""Orphanet:79105""|panther:PTHR46004(orthology-group)"	refseq:YP_170058.1|refseq:WP_003026641.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7ShdjPSg0OzpWR5cof228Ebx+lI9606	rogid:v1mSgBDe90RxW8uHIi9a67zCxJs177416	intact-crc:FB238D9351DF9250|rigid:kxfZh+wbAWUEtBhpzBMrQBA4jfk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIE3	uniprotkb:Q9BQ61	intact:EBI-2796495|uniprotkb:A0A0G2RMK7	intact:EBI-744881|ensembl:ENSP00000242784.3	psi-mi:q5nie3_fratt(display_long)|uniprotkb:glpA(gene name)|psi-mi:glpA(display_short)|uniprotkb:FTT_0132(locus name)	psi-mi:trir_human(display_long)|uniprotkb:TRIR(gene name)|psi-mi:TRIR(display_short)|uniprotkb:C19orf43(gene name synonym)|uniprotkb:Exoribonuclease TRIR(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807590|imex:IM-13779-1164	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0046168""(glycerol-3-phosphate catabolic process)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|refseq:YP_169199.1|interpro:IPR031656|refseq:WP_003019889.1|interpro:IPR038299|interpro:IPR036188"	"refseq:NP_076943.1|refseq:NP_001316667.1|ensembl:ENSG00000123144.11(gene)|ensembl:ENST00000242784.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0008409""(5'-3' exonuclease activity)|go:""GO:0016075""(rRNA catabolic process)|interpro:IPR038838|mint:Q9BQ61|panther:PTHR34753(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GyFomaYDqS6Ilatd7Qqp1Yo0a8M177416	rogid:8oDbNDhz5798Vmd+iPuLCh14ia09606	intact-crc:AC04DCFE9E918A72|rigid:27BHjkhdKWjR3PbyyMeXZoa36Ek	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BZJ0	uniprotkb:Q5NIP5	intact:EBI-1049701|uniprotkb:Q5JY64|uniprotkb:Q8WYI5|uniprotkb:Q9BZI9|uniprotkb:Q9BZJ1|uniprotkb:Q9BZJ2|uniprotkb:Q9GZW7|uniprotkb:Q9H8F8|uniprotkb:Q9NQH5|uniprotkb:Q9NYD8|uniprotkb:A8K9T4|ensembl:ENSP00000366557.2	intact:EBI-2797625	psi-mi:crnl1_human(display_long)|uniprotkb:Crooked neck homolog(gene name synonym)|uniprotkb:CRNKL1(gene name)|psi-mi:CRNKL1(display_short)|uniprotkb:CRN(gene name synonym)|uniprotkb:CGI-201(orf name)|uniprotkb:MSTP021(orf name)	psi-mi:gatb_fratt(display_long)|uniprotkb:FTT_0021(locus name)|uniprotkb:gatB(gene name)|psi-mi:gatB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807608|imex:IM-13779-1165	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001265554.1|refseq:NP_001265555.1|refseq:NP_001265556.1|refseq:NP_001265557.1|refseq:NP_057736.4|ensembl:ENSG00000101343.15(gene)|ensembl:ENST00000377340.6(transcript)|go:""GO:0000245""(spliceosomal complex assembly)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000974""(Prp19 complex)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071014""(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR045075|mint:Q9BZJ0|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7ABI|rcsb pdb:7DVQ|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8RO2|rcsb pdb:9FMD|reactome:R-HSA-72163|panther:PTHR11246(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0050566""(""asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0070681""(glutaminyl-tRNAGln biosynthesis via transamidation)|interpro:IPR017959|interpro:IPR006075(GatB N-terminal region)|interpro:IPR018027|interpro:IPR003789(GatB/Yqey)|interpro:IPR023168|interpro:IPR004413(""Glutamyl-tRNA(Gln) amidotransferase B subunit"")|interpro:IPR017958|refseq:YP_169097.1|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|refseq:WP_003017411.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/ikTGqhfoL3AVhgj8s6hP6pY0Yc9606	rogid:MULE4syC9yNG02pvDj3Le0UVDRw177416	intact-crc:D41CCC772D61CDE7|rigid:MfeN/ERNTdCY+rePubg51WOGDV8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q4VP87	uniprotkb:Q86Y74	intact:EBI-2796861	intact:EBI-2807597	psi-mi:q4vp87_fratl(display_long)|uniprotkb:FTT0445(orf name)|uniprotkb:uup(gene name)|psi-mi:uup(display_short)	psi-mi:q86y74_human(display_long)|uniprotkb:CROP(gene name)|psi-mi:CROP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807601|imex:IM-13779-1162	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|interpro:IPR027417|interpro:IPR032781|interpro:IPR051309"	"interpro:IPR004882(LUC7 related)|refseq:NP_057508.2|go:""GO:0003729""(mRNA binding)|go:""GO:0005685""(U1 snRNP)|go:""GO:0006376""(mRNA splice site recognition)|go:""GO:0016607""(nuclear speck)|refseq:NP_001317259.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+Qbmzj8eW72wb4LBUxcHkhpPQRE119856	rogid:JvIwNU4c0/YPGKguuzy2vJNE5Ro9606	intact-crc:18705360B520A18A|rigid:1nwUPy7H42ZVzwheqHkgtvdZUrI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI93	uniprotkb:Q16630	intact:EBI-2796455|uniprotkb:A0A0G2RN73	intact:EBI-358410|uniprotkb:Q53ES1|uniprotkb:Q9BSJ7|uniprotkb:Q9BW18|intact:EBI-740029|uniprotkb:A8K7K9|ensembl:ENSP00000391774.2	psi-mi:q5ni93_fratt(display_long)|uniprotkb:ftsZ(gene name)|psi-mi:ftsZ(display_short)|uniprotkb:FTT_0188(locus name)	psi-mi:cpsf6_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807656|imex:IM-13779-1167	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000917""(division septum assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|go:""GO:0051258""(protein polymerization)|refseq:YP_169249.1|interpro:IPR020805|interpro:IPR000158(Cell division protein FtsZ, N-terminal)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR037103|interpro:IPR024757|refseq:WP_003017491.1|interpro:IPR036525|interpro:IPR045061"	"panther:PTHR23204(orthology-group)|refseq:NP_008938.2|ensembl:ENSG00000111605.18(gene)|ensembl:ENST00000435070.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005726""(perichromatin fibrils)|go:""GO:0005737""(cytoplasm)|go:""GO:0005847""(mRNA cleavage and polyadenylation specificity factor complex)|go:""GO:0005849""(mRNA cleavage factor complex)|go:""GO:0006397""(mRNA processing)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0035061""(interchromatin granule)|go:""GO:0042382""(paraspeckles)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0046833""(positive regulation of RNA export from nucleus)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051290""(protein heterotetramerization)|go:""GO:0110104""(mRNA alternative polyadenylation)|go:""GO:0180010""(co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway)|go:""GO:1990448""(exon-exon junction complex binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979|mint:Q16630|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:4B4N|rcsb pdb:4U0A|rcsb pdb:4U0B|rcsb pdb:4WYM|rcsb pdb:6AY9|rcsb pdb:6GX9|rcsb pdb:7SNQ|rcsb pdb:7ZUD|rcsb pdb:8CL1|rcsb pdb:8EJL|rcsb pdb:8GDV|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001287876.1|dip:DIP-34501N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:p6oFxKWqOxuojnYBsnj2aLlMQbw177416	rogid:nvZBuI+X/m+5MGIsfh2ToVe5nFs9606	intact-crc:61EBE8126F9E0DB8|rigid:3tSu/UudGwYjqgan5MNY121m8co	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIN7	uniprotkb:Q8WU58	intact:EBI-2807639|uniprotkb:A0A0G2RPY1	intact:EBI-2807642|uniprotkb:Q9H6F3|uniprotkb:Q9NXN6|uniprotkb:Q9NVJ4|ensembl:ENSP00000413645.3|ensembl:ENSP00000462419.1|ensembl:ENSP00000463296.2|ensembl:ENSP00000463642.2|ensembl:ENSP00000464299.2|ensembl:ENSP00000464355.2	psi-mi:q5nin7_fratt(display_long)|uniprotkb:FTT_0029c(locus name)	psi-mi:f222b_human(display_long)|uniprotkb:FAM222B(gene name)|psi-mi:FAM222B(display_short)|uniprotkb:C17orf63(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807649|imex:IM-13779-1168	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR037455|refseq:YP_169105.1|interpro:IPR007310(IucA/IucC)|interpro:IPR022770|go:""GO:0019290""(siderophore biosynthetic process)|refseq:WP_003022888.1"	"refseq:NP_001275560.1|refseq:NP_001275561.1|refseq:NP_001275562.1|refseq:NP_001275563.1|refseq:NP_001275564.1|refseq:NP_001275565.1|refseq:NP_001275566.1|refseq:NP_001275567.1|refseq:NP_001275568.1|refseq:NP_001275569.1|refseq:NP_001070966.1|refseq:NP_060652.2|ensembl:ENSG00000173065.14(gene)|ensembl:ENST00000452648.8(transcript)|ensembl:ENST00000577376.6(transcript)|ensembl:ENST00000577513.6(transcript)|ensembl:ENST00000581229.6(transcript)|ensembl:ENST00000581407.6(transcript)|ensembl:ENST00000583307.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|interpro:IPR029340|refseq:XP_016880320.1|refseq:XP_016880321.1|refseq:XP_016880322.1|refseq:XP_016880323.1|panther:PTHR16070(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7lvwwb0cYSmlsKf9OOMAVmk8MOo177416	rogid:eRCYCsur959SVo1D/S8UADwRm009606	intact-crc:40E507BDE7AE3FB2|rigid:k/nm7h046Dy6waeAkbjbm+2zXG4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:P17927	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-2807625|uniprotkb:Q5SR43|uniprotkb:Q9UQV2|uniprotkb:Q5SR45|uniprotkb:Q16745|uniprotkb:Q16744|ensembl:ENSP00000356018.1|ensembl:ENSP00000356020.1|ensembl:ENSP00000383744.2	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:cr1_human(display_long)|uniprotkb:CR1(gene name)|psi-mi:CR1(display_short)|uniprotkb:C3BR(gene name synonym)|uniprotkb:C3b/C4b receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807622|imex:IM-13779-1166	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"refseq:NP_000564.2|refseq:NP_000642.3|ensembl:ENSG00000203710.12(gene)|ensembl:ENST00000367051.6(transcript)|ensembl:ENST00000367053.6(transcript)|ensembl:ENST00000400960.7(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0001855""(complement component C4b binding)|go:""GO:0001861""(complement component C4b receptor activity)|go:""GO:0001970""(positive regulation of activation of membrane attack complex)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0002430""(complement receptor mediated signaling pathway)|go:""GO:0002435""(immune complex clearance by erythrocytes)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0002638""(negative regulation of immunoglobulin production)|go:""GO:0004877""(complement component C3b receptor activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045591""(positive regulation of regulatory T cell differentiation)|go:""GO:0045916""(negative regulation of complement activation)|go:""GO:0045957""(negative regulation of complement activation, alternative pathway)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1900004""(negative regulation of serine-type endopeptidase activity)|go:""GO:1900005""(positive regulation of serine-type endopeptidase activity)|go:""GO:1900099""(negative regulation of plasma cell differentiation)|go:""GO:1903660""(negative regulation of complement-dependent cytotoxicity)|go:""GO:1904669""(ATP export)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051277|rcsb pdb:1GKG|rcsb pdb:1GKN|rcsb pdb:1PPQ|rcsb pdb:2MCY|rcsb pdb:2MCZ|rcsb pdb:2Q7Z|rcsb pdb:5FO9|reactome:R-HSA-6798695|reactome:R-HSA-8877330|reactome:R-HSA-977606|panther:PTHR19325(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:gwNvQZmPMP1PCX8z/svSxkVBZt49606	intact-crc:4DA770FDE640B47C|rigid:+QCiRfTs7Mv2J+jva2Nch6dqpWs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04632	uniprotkb:Q5NGR3	intact:EBI-711828|ensembl:ENSP00000246533.2|ensembl:ENSP00000464849.1|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1	intact:EBI-2796275	psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym)	psi-mi:seca_fratt(display_long)|uniprotkb:FTT_0769(locus name)|uniprotkb:secA(gene name)|psi-mi:secA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807663|imex:IM-13779-1170	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000126247.11(gene)|ensembl:ENST00000246533.8(transcript)|ensembl:ENST00000588815.5(transcript)|go:""GO:0004198""(calcium-dependent cysteine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0110158""(calpain complex)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:XP_005259352.1|refseq:XP_005259353.1|refseq:NP_001289561.1|refseq:NP_001289562.1|panther:PTHR46735(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0017038""(protein import)|go:""GO:0031522""(cell envelope Sec protein transport complex)|go:""GO:0043952""(protein transport by the Sec complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0065002""(intracellular protein transmembrane transport)|refseq:YP_169779.1|interpro:IPR004027(SEC-C motif)|interpro:IPR000185(SecA protein)|interpro:IPR020937|interpro:IPR011115(SecA DEAD-like)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR044722|interpro:IPR027417|refseq:WP_011242256.1|interpro:IPR036266|interpro:IPR036670"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606	rogid:c80pRjALHg9VjvniwOaxVtBGz4w177416	intact-crc:E665693E96B12193|rigid:wMeveqOBq3ZtpbCBQ96Mrak+xuU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q66GS9	uniprotkb:Q5NEC0	intact:EBI-1046993|uniprotkb:O75130|uniprotkb:Q9H8H7|uniprotkb:B2RMY0|uniprotkb:Q58F25|ensembl:ENSP00000257287.3|intact:EBI-1058323	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:cp135_human(display_long)|uniprotkb:Centrosomal protein 4(gene name synonym)|uniprotkb:CEP135(gene name)|psi-mi:CEP135(display_short)|uniprotkb:CEP4(gene name synonym)|uniprotkb:KIAA0635(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807684|imex:IM-13779-1173	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000174799.12(gene)|ensembl:ENST00000257287.5(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0007099""(centriole replication)|go:""GO:0008017""(microtubule binding)|go:""GO:0010457""(centriole-centriole cohesion)|go:""GO:0015631""(tubulin binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:1902857""(positive regulation of non-motile cilium assembly)|go:""GO:1904951""(positive regulation of establishment of protein localization)|interpro:IPR051877|mint:Q66GS9|rcsb pdb:5FCN|rcsb pdb:5NG4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_079285.2|dip:DIP-50271N|efo:""Orphanet:2512""|panther:PTHR23159(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:x/sbJVIQUS2zD/l2SQsmV5HwKP89606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:FB462D597889D6B1|rigid:fWg+W/vCONC9ThH277BYHKs+dFs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:Q9BQ65	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-2807694|uniprotkb:Q96FZ9|uniprotkb:Q9H8X8|uniprotkb:B4DWE3|uniprotkb:B4DZW5|ensembl:ENSP00000219281.3	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:usb1_human(display_long)|uniprotkb:USB1(gene name)|psi-mi:USB1(display_short)|uniprotkb:C16orf57(gene name synonym)|uniprotkb:3'-5' RNA exonuclease USB1(gene name synonym)|uniprotkb:Mpn1(gene name synonym)|uniprotkb:Mutated in poikiloderma with neutropenia protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807691|imex:IM-13779-1172	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"ensembl:ENSG00000103005.13(gene)|ensembl:ENST00000219281.8(transcript)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016829""(lyase activity)|go:""GO:0034472""(snRNA 3'-end processing)|go:""GO:0034477""(U6 snRNA 3'-end processing)|go:""GO:0045171""(intercellular bridge)|go:""GO:1990838""(""poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends"")|interpro:IPR027521|mint:Q9BQ65|rcsb pdb:4H7W|rcsb pdb:5V1M|rcsb pdb:6D2Z|rcsb pdb:6D30|rcsb pdb:6D31|refseq:NP_001182231.1|refseq:NP_001191840.1|refseq:NP_001317497.1|refseq:NP_078874.2|efo:""Orphanet:1775""|efo:""Orphanet:221046""|panther:PTHR13522(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:eJ9a4DRT7vAPnA9W5Fm44tNHiBE9606	intact-crc:14BC2FF7A3DC8169|rigid:j24YAsnbFIJBpBV4qZP+brED38g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGW2	uniprotkb:Q6FI81	intact:EBI-2796474|uniprotkb:A0A0G2RND5	intact:EBI-750511|uniprotkb:O75206|uniprotkb:O75207|uniprotkb:Q9H0W1|uniprotkb:Q9P1L7|uniprotkb:A8K8B6|ensembl:ENSP00000377914.4	psi-mi:q5ngw2_fratt(display_long)|uniprotkb:FTT_0715(locus name)	psi-mi:cpin1_human(display_long)|uniprotkb:Cytokine-induced apoptosis inhibitor 1(gene name synonym)|uniprotkb:CIAPIN1(gene name)|psi-mi:CIAPIN1(display_short)|uniprotkb:PRO0915(orf name)|uniprotkb:CUA001(orf name)|uniprotkb:Fe-S cluster assembly protein DRE2 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807677|imex:IM-13779-1171	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0004568""(chitinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR029070|refseq:YP_169730.1|interpro:IPR003610(Carbohydrate-binding family V/XII)|interpro:IPR011583(Chitinase II)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_003020524.1|interpro:IPR036116|interpro:IPR036573|interpro:IPR050314"	"refseq:NP_064709.2|ensembl:ENSG00000005194.15(gene)|refseq:NP_001295276.1|refseq:NP_001295287.1|ensembl:ENST00000394391.9(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006915""(apoptotic process)|go:""GO:0009055""(electron transfer activity)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0030097""(hemopoiesis)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR029063|interpro:IPR046408|interpro:IPR049011|mint:Q6FI81|rcsb pdb:2LD4|rcsb pdb:2YUI|rcsb pdb:4M7R|reactome:R-HSA-2564830|dip:DIP-61697N|panther:PTHR13273(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hPHdF34TD5FCXE5bWyEmg/dd7sg177416	rogid:80r/MAg7g8AcGJc7SGHsjE5aWiA9606	intact-crc:73A669A64C468F4F|rigid:/2B43GdnGqkbN3SAK4F8Datbm4w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6FI81	uniprotkb:Q5NIF3	intact:EBI-750511|uniprotkb:O75206|uniprotkb:O75207|uniprotkb:Q9H0W1|uniprotkb:Q9P1L7|uniprotkb:A8K8B6|ensembl:ENSP00000377914.4	intact:EBI-2805542|uniprotkb:A0A0G2RQ85	psi-mi:cpin1_human(display_long)|uniprotkb:Cytokine-induced apoptosis inhibitor 1(gene name synonym)|uniprotkb:CIAPIN1(gene name)|psi-mi:CIAPIN1(display_short)|uniprotkb:PRO0915(orf name)|uniprotkb:CUA001(orf name)|uniprotkb:Fe-S cluster assembly protein DRE2 homolog(gene name synonym)	psi-mi:q5nif3_fratt(display_long)|uniprotkb:FTT_0119(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807670|imex:IM-13779-1169	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_064709.2|ensembl:ENSG00000005194.15(gene)|refseq:NP_001295276.1|refseq:NP_001295287.1|ensembl:ENST00000394391.9(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006915""(apoptotic process)|go:""GO:0009055""(electron transfer activity)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0030097""(hemopoiesis)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR029063|interpro:IPR046408|interpro:IPR049011|mint:Q6FI81|rcsb pdb:2LD4|rcsb pdb:2YUI|rcsb pdb:4M7R|reactome:R-HSA-2564830|dip:DIP-61697N|panther:PTHR13273(orthology-group)"	"interpro:IPR018392|refseq:YP_169189.1|go:""GO:0016020""(membrane)|refseq:WP_003019870.1|interpro:IPR036779"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:80r/MAg7g8AcGJc7SGHsjE5aWiA9606	rogid:h8z6Md6/RUQQaYkf/0SDUSXFJqs177416	intact-crc:2CE3C7A64C1FE013|rigid:+7kYvlnCIcRSrKLLh9X+p/vU12s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFM0	uniprotkb:P35606	intact:EBI-2800168|uniprotkb:A0A0G2RNN7	intact:EBI-1056534|ensembl:ENSP00000329419.4|uniprotkb:B4DZI8|intact:EBI-11019844	psi-mi:q5nfm0_fratt(display_long)|uniprotkb:FTT_1214c(locus name)	psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807725|imex:IM-13779-1175	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR000150(Cof protein)|refseq:YP_170172.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0016791""(phosphatase activity)|refseq:WP_003021483.1|interpro:IPR036412"	"ensembl:ENSG00000184432.11(gene)|ensembl:ENST00000333188.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0030126""(COPI vesicle coat)|go:""GO:0030133""(transport vesicle)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|interpro:IPR050844|mint:P35606|rcsb pdb:8D30|rcsb pdb:8D41|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_004757.1|refseq:XP_016863001.1|efo:""Orphanet:2512""|dip:DIP-27603N|panther:PTHR19876(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:sGXWuuIontV2yTFO4nOU2nzzlbI177416	rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606	intact-crc:52C5AB11F70CB3E0|rigid:T5Jxw/Xoaf6FG1+/7vh9MCp6RjM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID9	uniprotkb:P31146	intact:EBI-2798201	intact:EBI-1046676|ensembl:ENSP00000219150.6|ensembl:ENSP00000455552.1|uniprotkb:Q2YD73|uniprotkb:B2RBL1	psi-mi:eftu_fratt(display_long)|uniprotkb:FTT_0137(locus name)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)	psi-mi:cor1a_human(display_long)|uniprotkb:Coronin-like protein p57(gene name synonym)|uniprotkb:Coronin-like protein A(gene name synonym)|uniprotkb:Tryptophan aspartate-containing coat protein(gene name synonym)|uniprotkb:CORO1A(gene name)|psi-mi:CORO1A(display_short)|uniprotkb:CORO1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807718|imex:IM-13779-1177	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0097216""(guanosine tetraphosphate binding)|refseq:YP_169203.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR033720|interpro:IPR031157|refseq:WP_003028672.1|interpro:IPR041709|interpro:IPR050055"	"ensembl:ENSG00000102879.17(gene)|ensembl:ENST00000219150.10(transcript)|ensembl:ENST00000570045.5(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0001845""(phagolysosome assembly)|go:""GO:0001891""(phagocytic cup)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0003785""(actin monomer binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0006909""(phagocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010631""(epithelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030424""(axon)|go:""GO:0030595""(leukocyte chemotaxis)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031339""(negative regulation of vesicle fusion)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0032036""(myosin heavy chain binding)|go:""GO:0032796""(uropod organization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0038180""(nerve growth factor signaling pathway)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043320""(natural killer cell degranulation)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051015""(actin filament binding)|go:""GO:0051126""(negative regulation of actin nucleation)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0061502""(early endosome to recycling endosome transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071353""(cellular response to interleukin-4)|go:""GO:0072679""(thymocyte migration)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000406""(positive regulation of T cell migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015049(Region of unknown function DUF1900)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P31146|reactome:R-HSA-9636383|refseq:NP_001180262.1|refseq:NP_009005.1|refseq:XP_011544016.1|efo:""Orphanet:228003""|panther:PTHR10856(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h5xJZCtwL77bt8cg/p85MmX1c+E177416	rogid:p2NmQ7YE3FUzyW0Op4rLPLFaVVU9606	intact-crc:81C80E16FC20B2A4|rigid:RNIRgv6xrtT/iZ/Iq+SuROBIgBA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H0I2	uniprotkb:Q5NID9	intact:EBI-744099|uniprotkb:Q6UWD7|ensembl:ENSP00000243878.4	intact:EBI-2798201	psi-mi:enkd1_human(display_long)|uniprotkb:ENKD1(gene name)|psi-mi:ENKD1(display_short)|uniprotkb:C16orf48(gene name synonym)|uniprotkb:UNQ6410/PRO21183(orf name)	psi-mi:eftu_fratt(display_long)|uniprotkb:FTT_0137(locus name)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807704|imex:IM-13779-1176	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115516.1|ensembl:ENSG00000124074.12(gene)|ensembl:ENST00000243878.9(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000922""(spindle pole)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0044458""(motile cilium assembly)|go:""GO:0097546""(ciliary base)|go:""GO:0097731""(9+0 non-motile cilium)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR027012|interpro:IPR052102|mint:Q9H0I2|panther:PTHR21490(orthology-group)"	"go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0097216""(guanosine tetraphosphate binding)|refseq:YP_169203.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR033720|interpro:IPR031157|refseq:WP_003028672.1|interpro:IPR041709|interpro:IPR050055"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kLnlpnGpF+sgQ+umqiN1CIK/7wc9606	rogid:h5xJZCtwL77bt8cg/p85MmX1c+E177416	intact-crc:41A01A4C7B0C43D3|rigid:X/g0zuNLKM2hq3gJCz8XTFEDJCg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86VX2	uniprotkb:Q5NE83	intact:EBI-1550280|uniprotkb:A2BHJ2|uniprotkb:Q5JYB0|uniprotkb:Q96SI7|uniprotkb:Q9BW53|uniprotkb:B3KTZ2|ensembl:ENSP00000278980.6	intact:EBI-2798034|uniprotkb:A0A0G2RMP3	psi-mi:comd7_human(display_long)|uniprotkb:COMMD7(gene name)|psi-mi:COMMD7(display_short)|uniprotkb:C20orf92(gene name synonym)	psi-mi:q5ne83_fratt(display_long)|uniprotkb:FTT_1768c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807732|imex:IM-13779-1178	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001092809.1|refseq:NP_444269.2|ensembl:ENSG00000149600.12(gene)|ensembl:ENST00000278980.11(transcript)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051059""(NF-kappaB binding)|interpro:IPR017920|interpro:IPR037358|interpro:IPR047155|mint:Q86VX2|rcsb pdb:8ESD|rcsb pdb:8F2R|rcsb pdb:8F2U|rcsb pdb:8P0W|reactome:R-HSA-8951664|panther:PTHR16231(orthology-group)"	"go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008843""(endochitinase activity)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:YP_170659.1|interpro:IPR050542"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9mVwUwXsqGS+xFwRa4KbMylvaps9606	rogid:W2y1WmdkLbyjKn567ANSSuNPpHo177416	intact-crc:E0CDAE4BA3ACF260|rigid:e0UMTKrrKfzG5wbY2P9p0HgCX5U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31146	uniprotkb:Q5NIE3	intact:EBI-1046676|ensembl:ENSP00000219150.6|ensembl:ENSP00000455552.1|uniprotkb:Q2YD73|uniprotkb:B2RBL1	intact:EBI-2796495|uniprotkb:A0A0G2RMK7	psi-mi:cor1a_human(display_long)|uniprotkb:Coronin-like protein p57(gene name synonym)|uniprotkb:Coronin-like protein A(gene name synonym)|uniprotkb:Tryptophan aspartate-containing coat protein(gene name synonym)|uniprotkb:CORO1A(gene name)|psi-mi:CORO1A(display_short)|uniprotkb:CORO1(gene name synonym)	psi-mi:q5nie3_fratt(display_long)|uniprotkb:glpA(gene name)|psi-mi:glpA(display_short)|uniprotkb:FTT_0132(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807711|imex:IM-13779-1174	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000102879.17(gene)|ensembl:ENST00000219150.10(transcript)|ensembl:ENST00000570045.5(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0001845""(phagolysosome assembly)|go:""GO:0001891""(phagocytic cup)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0003785""(actin monomer binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0006909""(phagocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010631""(epithelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030424""(axon)|go:""GO:0030595""(leukocyte chemotaxis)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031339""(negative regulation of vesicle fusion)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0032036""(myosin heavy chain binding)|go:""GO:0032796""(uropod organization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0038180""(nerve growth factor signaling pathway)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043320""(natural killer cell degranulation)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051015""(actin filament binding)|go:""GO:0051126""(negative regulation of actin nucleation)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0061502""(early endosome to recycling endosome transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071353""(cellular response to interleukin-4)|go:""GO:0072679""(thymocyte migration)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000406""(positive regulation of T cell migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015049(Region of unknown function DUF1900)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P31146|reactome:R-HSA-9636383|refseq:NP_001180262.1|refseq:NP_009005.1|refseq:XP_011544016.1|efo:""Orphanet:228003""|panther:PTHR10856(orthology-group)"	"go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0046168""(glycerol-3-phosphate catabolic process)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|refseq:YP_169199.1|interpro:IPR031656|refseq:WP_003019889.1|interpro:IPR038299|interpro:IPR036188"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:p2NmQ7YE3FUzyW0Op4rLPLFaVVU9606	rogid:GyFomaYDqS6Ilatd7Qqp1Yo0a8M177416	intact-crc:96B90E16FE7EEB62|rigid:kvsSgPTsm/Pprcw29S9QacnWinA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UP83	uniprotkb:Q5NGF9	intact:EBI-389502|uniprotkb:A4D0R6|uniprotkb:A4D0R7|uniprotkb:Q6NUL5|uniprotkb:O14555|uniprotkb:O95008	intact:EBI-2796712|uniprotkb:A0A0G2RMW7	psi-mi:cog5_human(display_long)|uniprotkb:COG5(gene name)|psi-mi:COG5(display_short)|uniprotkb:GOLTC1(gene name synonym)|uniprotkb:GTC90(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 5(gene name synonym)|uniprotkb:13S Golgi transport complex 90 kDa subunit(gene name synonym)|uniprotkb:Golgi transport complex 1(gene name synonym)	psi-mi:q5ngf9_fratt(display_long)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:FTT_0886(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807746|imex:IM-13779-1181	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000139""(Golgi membrane)|go:""GO:0000301""(retrograde transport, vesicle recycling within Golgi)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0048219""(inter-Golgi cisterna vesicle-mediated transport)|go:""GO:0070085""(glycosylation)|interpro:IPR019465|interpro:IPR048485|interpro:IPR049176|mint:Q9UP83|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_001154992.1|refseq:NP_006339.3|refseq:NP_859422.2|efo:""Orphanet:263487""|panther:PTHR13228(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|refseq:YP_169883.1|interpro:IPR027417|refseq:WP_003020876.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Z0P9dJYRhOr/TNyO7LwsuzNkInA9606	rogid:OSkw64bDGErXabpL9In6RSfdCEQ177416	intact-crc:D31BD84D7DE50763|rigid:Xi9xgREMiwWaBA0NMY/hMj9qpfk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96JB2	uniprotkb:Q5NEY1	intact:EBI-2807756|uniprotkb:Q5VT70|uniprotkb:B2RAW5|uniprotkb:Q9BZ92|uniprotkb:Q8IXX4|ensembl:ENSP00000258654.8	intact:EBI-2797409|uniprotkb:A0A0G2RN51	psi-mi:cog3_human(display_long)|uniprotkb:COG3(gene name)|psi-mi:COG3(display_short)|uniprotkb:SEC34(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 3(gene name synonym)|uniprotkb:Vesicle-docking protein SEC34 homolog(gene name synonym)|uniprotkb:p94(gene name synonym)	psi-mi:q5ney1_fratt(display_long)|uniprotkb:galT(gene name)|psi-mi:galT(display_short)|uniprotkb:FTT_1475(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807753|imex:IM-13779-1180	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_113619.2|ensembl:ENSG00000136152.15(gene)|ensembl:ENST00000349995.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000301""(retrograde transport, vesicle recycling within Golgi)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0033365""(protein localization to organelle)|go:""GO:0050821""(protein stabilization)|go:""GO:0070085""(glycosylation)|interpro:IPR007265(Sec34-like protein)|interpro:IPR048320|interpro:IPR048685|mint:Q96JB2|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|panther:PTHR13302(orthology-group)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0008108""(""UDP-glucose:hexose-1-phosphate uridylyltransferase activity"")|go:""GO:0008270""(zinc ion binding)|go:""GO:0033499""(galactose catabolic process via UDP-galactose, Leloir pathway)|interpro:IPR001937(Galactose-1-phosphate uridyl transferase, class I)|interpro:IPR019779|interpro:IPR005850(Galactose-1-phosphate uridyl transferase, C-terminal)|interpro:IPR005849(Galactose-1-phosphate uridyl transferase, N-terminal)|refseq:YP_170411.1|refseq:WP_003022328.1|interpro:IPR036265"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:P3sc7TLrhgqNPIh7VYpmsoIhSrE9606	rogid:smALYBvkGhvYCWC0C9zeLdYDAMs177416	intact-crc:15C0FBD31DF86496|rigid:sX+l2AmDuXo1CShhQHylVFw6iJQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96MW5	uniprotkb:Q5NFN3	intact:EBI-720875|uniprotkb:Q8WVV6|uniprotkb:Q9H6F8|uniprotkb:Q0VAK2|ensembl:ENSP00000305459.6	intact:EBI-2799271|uniprotkb:A0A0G2RMM7	psi-mi:cog8_human(display_long)|uniprotkb:Component of oligomeric Golgi complex 8(gene name synonym)|uniprotkb:COG8(gene name)|psi-mi:COG8(display_short)	psi-mi:q5nfn3_fratt(display_long)|uniprotkb:sbcB(gene name)|psi-mi:sbcB(display_short)|uniprotkb:FTT_1200c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807739|imex:IM-13779-1179	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:95428""|ensembl:ENSG00000213380.16(gene)|ensembl:ENST00000306875.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000301""(retrograde transport, vesicle recycling within Golgi)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0070085""(glycosylation)|interpro:IPR007255(Dor1-like protein)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR016632(Conserved oligomeric Golgi complex, COG8)|mint:Q96MW5|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_115758.3|panther:PTHR21311(orthology-group)"	"interpro:IPR023607|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:YP_170159.1|interpro:IPR034747|interpro:IPR034748|go:""GO:0003677""(DNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0008310""(single-stranded DNA 3'-5' DNA exonuclease activity)|go:""GO:0045004""(DNA replication proofreading)|go:""GO:0046872""(metal ion binding)|refseq:WP_003021452.1|interpro:IPR013620(Exonuclease C-terminal)|interpro:IPR036397"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:X9AZmEQ+B2Jc9kwFXAgxZp6S0sI9606	rogid:mZbdpZ1MtY92QBknO89wpvreVGg177416	intact-crc:510C866C27810823|rigid:N8awonDwYnFAEHzhiY+EfLiQI3s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96CD2	uniprotkb:Q5NEW4	intact:EBI-724333|uniprotkb:Q96SX0|uniprotkb:Q9HC17|ensembl:ENSP00000343190.3	intact:EBI-2804278|uniprotkb:A0A0G2RNG0	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:q5new4_fratt(display_long)|uniprotkb:FTT_1493c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807768|imex:IM-13779-1182	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_068595.3|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1|ensembl:ENSG00000138621.12(gene)|ensembl:ENST00000342932.8(transcript)|go:""GO:0004633""(phosphopantothenoylcysteine decarboxylase activity)|go:""GO:0005829""(cytosol)|go:""GO:0010181""(FMN binding)|go:""GO:0015937""(coenzyme A biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0071513""(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|mint:Q96CD2|rcsb pdb:1QZU|reactome:R-HSA-196783|panther:PTHR14359(orthology-group)"	refseq:YP_170428.1|refseq:WP_003022358.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	rogid:27huGXtUR7EE86YZGD/S43e1SDg177416	intact-crc:7CE7812A14FD7CC5|rigid:STmwiri7nhY3RBb91YBh6kLjHKs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P12109	uniprotkb:Q5NHN4	intact:EBI-2465913|uniprotkb:O00117|uniprotkb:O00118|uniprotkb:Q14040|uniprotkb:Q14041|uniprotkb:Q16258|uniprotkb:Q7Z645|uniprotkb:Q9BSA8|ensembl:ENSP00000355180.3	intact:EBI-2797896	psi-mi:co6a1_human(display_long)|uniprotkb:COL6A1(gene name)|psi-mi:COL6A1(display_short)	"psi-mi:glgb_fratt(display_long)|uniprotkb:""1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase""(gene name synonym)|uniprotkb:FTT_0413c(locus name)|uniprotkb:glgB(gene name)|psi-mi:glgB(display_short)|uniprotkb:""Alpha-(1->4)-glucan branching enzyme""(gene name synonym)|uniprotkb:Glycogen branching enzyme(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807782|imex:IM-13779-1186	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000142156.16(gene)|ensembl:ENST00000361866.8(transcript)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001942""(hair follicle development)|go:""GO:0002023""(reduction of food intake in response to dietary excess)|go:""GO:0003012""(muscle system process)|go:""GO:0003016""(respiratory system process)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005589""(collagen type VI trimer)|go:""GO:0005604""(basement membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006096""(glycolytic process)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0006112""(energy reserve metabolic process)|go:""GO:0006914""(autophagy)|go:""GO:0006954""(inflammatory response)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007338""(single fertilization)|go:""GO:0007507""(heart development)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009411""(response to UV)|go:""GO:0009611""(response to wounding)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010467""(gene expression)|go:""GO:0010657""(muscle cell apoptotic process)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016020""(membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019226""(transmission of nerve impulse)|go:""GO:0022011""(myelination in peripheral nervous system)|go:""GO:0030016""(myofibril)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030262""(apoptotic nuclear changes)|go:""GO:0030282""(bone mineralization)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032963""(collagen metabolic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0036022""(limb joint morphogenesis)|go:""GO:0036293""(response to decreased oxygen levels)|go:""GO:0042383""(sarcolemma)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048265""(response to pain)|go:""GO:0048286""(lung alveolus development)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048630""(skeletal muscle tissue growth)|go:""GO:0048741""(skeletal muscle fiber development)|go:""GO:0048771""(tissue remodeling)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050954""(sensory perception of mechanical stimulus)|go:""GO:0051216""(cartilage development)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051882""(mitochondrial depolarization)|go:""GO:0060065""(uterus development)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060348""(bone development)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0060487""(lung epithelial cell differentiation)|go:""GO:0060612""(adipose tissue development)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070341""(fat cell proliferation)|go:""GO:0070836""(caveola assembly)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0071965""(multicellular organismal locomotion)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0085029""(extracellular matrix assembly)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0098528""(skeletal muscle fiber differentiation)|go:""GO:1901652""(response to peptide)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904583""(response to polyamine macromolecule)|go:""GO:1904975""(response to bleomycin)|go:""GO:1990542""(mitochondrial transmembrane transport)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR036465|interpro:IPR050525|mint:P12109|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8948216|refseq:NP_001839.2|efo:""Orphanet:610""|efo:""Orphanet:646098""|efo:""Orphanet:646113""|efo:""Orphanet:75840""|panther:PTHR24020(orthology-group)"	"go:""GO:0003844""(1,4-alpha-glucan branching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005829""(cytosol)|go:""GO:0005978""(glycogen biosynthetic process)|go:""GO:0043169""(cation binding)|interpro:IPR037439|interpro:IPR044143|refseq:YP_169458.1|interpro:IPR006407(1,4-alpha-glucan branching enzyme, core region)|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_003020147.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ziEV+a4Xb+C4ioMe8uoISJitR6E9606	rogid:r21IlnrFbxbAaYAD68mDKpyeQwI177416	intact-crc:482A9029C7BF292E|rigid:7JWsUNKhEwZfSstJ7b44msux3Xo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH48	uniprotkb:P08572	intact:EBI-2796433	intact:EBI-2432506|uniprotkb:Q14052|uniprotkb:Q548C3|uniprotkb:Q5VZA9|uniprotkb:Q66K23|ensembl:ENSP00000353654.5|ensembl:ENSP00000383027.4	psi-mi:tig_fratt(display_long)|uniprotkb:tig(gene name)|psi-mi:tig(display_short)|uniprotkb:PPIase(gene name synonym)|uniprotkb:FTT_0623(locus name)	psi-mi:co4a2_human(display_long)|uniprotkb:COL4A2(gene name)|psi-mi:COL4A2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807796|imex:IM-13779-1187	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0015031""(protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043335""(protein unfolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051301""(cell division)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR027304|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR005215(Trigger factor)|interpro:IPR008880(Trigger factor, C-terminal, bacterial)|interpro:IPR008881(Trigger factor, ribosome-binding, bacterial)|refseq:YP_169644.1|refseq:WP_003023405.1|interpro:IPR037041|interpro:IPR036611|interpro:IPR046357"	"reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8948216|refseq:NP_001837.2|efo:""Orphanet:36383""|ensembl:ENSG00000134871.20(gene)|ensembl:ENST00000360467.7(transcript)|ensembl:ENST00000400163.8(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005587""(collagen type IV trimer)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0014823""(response to activity)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0038063""(collagen-activated tyrosine kinase receptor signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036954|interpro:IPR050149|mint:P08572|rcsb pdb:1LI1|rcsb pdb:5NAX|rcsb pdb:5NB2|rcsb pdb:6MPX|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|efo:""Orphanet:99810""|panther:PTHR24023(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dsDJ/N33l7DfldUNxpAaQZZr/ug177416	rogid:2jSdn1hb9JtAPdSLo82KAbqdzr09606	intact-crc:16A939135C6C64D3|rigid:96DhKGrAI9wclcYhAmP53fv267Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEY0	uniprotkb:P12109	intact:EBI-2797481|uniprotkb:A0A0G2RMG0	intact:EBI-2465913|uniprotkb:O00117|uniprotkb:O00118|uniprotkb:Q14040|uniprotkb:Q14041|uniprotkb:Q16258|uniprotkb:Q7Z645|uniprotkb:Q9BSA8|ensembl:ENSP00000355180.3	psi-mi:q5ney0_fratt(display_long)|uniprotkb:Galactose kinase(gene name synonym)|uniprotkb:galK(gene name)|psi-mi:galK(display_short)|uniprotkb:FTT_1476(locus name)	psi-mi:co6a1_human(display_long)|uniprotkb:COL6A1(gene name)|psi-mi:COL6A1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807775|imex:IM-13779-1183	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000287""(magnesium ion binding)|go:""GO:0004335""(galactokinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006012""(galactose metabolic process)|refseq:YP_170412.1|interpro:IPR000705(Galactokinase)|interpro:IPR022963|interpro:IPR019741|interpro:IPR019539|interpro:IPR006204(GHMP kinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|refseq:WP_003022331.1|interpro:IPR036554"	"ensembl:ENSG00000142156.16(gene)|ensembl:ENST00000361866.8(transcript)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001942""(hair follicle development)|go:""GO:0002023""(reduction of food intake in response to dietary excess)|go:""GO:0003012""(muscle system process)|go:""GO:0003016""(respiratory system process)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005589""(collagen type VI trimer)|go:""GO:0005604""(basement membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006096""(glycolytic process)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0006112""(energy reserve metabolic process)|go:""GO:0006914""(autophagy)|go:""GO:0006954""(inflammatory response)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007338""(single fertilization)|go:""GO:0007507""(heart development)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009411""(response to UV)|go:""GO:0009611""(response to wounding)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010467""(gene expression)|go:""GO:0010657""(muscle cell apoptotic process)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016020""(membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019226""(transmission of nerve impulse)|go:""GO:0022011""(myelination in peripheral nervous system)|go:""GO:0030016""(myofibril)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030262""(apoptotic nuclear changes)|go:""GO:0030282""(bone mineralization)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032963""(collagen metabolic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0036022""(limb joint morphogenesis)|go:""GO:0036293""(response to decreased oxygen levels)|go:""GO:0042383""(sarcolemma)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048265""(response to pain)|go:""GO:0048286""(lung alveolus development)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048630""(skeletal muscle tissue growth)|go:""GO:0048741""(skeletal muscle fiber development)|go:""GO:0048771""(tissue remodeling)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050954""(sensory perception of mechanical stimulus)|go:""GO:0051216""(cartilage development)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051882""(mitochondrial depolarization)|go:""GO:0060065""(uterus development)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060348""(bone development)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0060487""(lung epithelial cell differentiation)|go:""GO:0060612""(adipose tissue development)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070341""(fat cell proliferation)|go:""GO:0070836""(caveola assembly)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0071965""(multicellular organismal locomotion)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0085029""(extracellular matrix assembly)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0098528""(skeletal muscle fiber differentiation)|go:""GO:1901652""(response to peptide)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904583""(response to polyamine macromolecule)|go:""GO:1904975""(response to bleomycin)|go:""GO:1990542""(mitochondrial transmembrane transport)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR036465|interpro:IPR050525|mint:P12109|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8948216|refseq:NP_001839.2|efo:""Orphanet:610""|efo:""Orphanet:646098""|efo:""Orphanet:646113""|efo:""Orphanet:75840""|panther:PTHR24020(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0I5F4clSaTeoy3ZN9JvG4E10EN0177416	rogid:ziEV+a4Xb+C4ioMe8uoISJitR6E9606	intact-crc:FC2EAD29C6C88E08|rigid:g+IY7wW4VSt+NNAnvlUDCRA9OFc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEH1	uniprotkb:P08572	intact:EBI-2796391|uniprotkb:A0A0G2RMG3	intact:EBI-2432506|uniprotkb:Q14052|uniprotkb:Q548C3|uniprotkb:Q5VZA9|uniprotkb:Q66K23|ensembl:ENSP00000353654.5|ensembl:ENSP00000383027.4	psi-mi:q5neh1_fratt(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:FTT_1664(locus name)	psi-mi:co4a2_human(display_long)|uniprotkb:COL4A2(gene name)|psi-mi:COL4A2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807803|imex:IM-13779-1185	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_170571.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|refseq:WP_003022611.1|interpro:IPR036897|interpro:IPR036914"	"reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8948216|refseq:NP_001837.2|efo:""Orphanet:36383""|ensembl:ENSG00000134871.20(gene)|ensembl:ENST00000360467.7(transcript)|ensembl:ENST00000400163.8(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005587""(collagen type IV trimer)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0014823""(response to activity)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0038063""(collagen-activated tyrosine kinase receptor signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036954|interpro:IPR050149|mint:P08572|rcsb pdb:1LI1|rcsb pdb:5NAX|rcsb pdb:5NB2|rcsb pdb:6MPX|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|efo:""Orphanet:99810""|panther:PTHR24023(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YUFWDuTGDB9kX/RHTWI6fMTHxU0177416	rogid:2jSdn1hb9JtAPdSLo82KAbqdzr09606	intact-crc:9FF604135EC60786|rigid:LsYSPOee7Uw5mO/Tlim7oGPxIqE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P0C0L4	uniprotkb:Q5NEM9	intact:EBI-1223619|uniprotkb:P01028|uniprotkb:P78445|uniprotkb:Q13160|uniprotkb:Q13906|uniprotkb:Q14033|uniprotkb:Q14835|uniprotkb:Q5JQM8|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:B0QZR6|uniprotkb:A6H8M8|uniprotkb:A6NHJ5|uniprotkb:A7E2V2|uniprotkb:B0V2C8|uniprotkb:B2RUT6|uniprotkb:B7ZVZ6|uniprotkb:Q4LE82|uniprotkb:Q5JNX2|uniprotkb:Q6P4R1|uniprotkb:Q6U2E5|uniprotkb:Q6U2E8|uniprotkb:Q6U2F0|uniprotkb:Q6U2F3|uniprotkb:Q6U2F4|uniprotkb:Q6U2F6|uniprotkb:Q6U2F8|uniprotkb:Q6U2G0|uniprotkb:Q96EG2|uniprotkb:Q96SA8|ensembl:ENSP00000372815.4|ensembl:ENSP00000388662.2|ensembl:ENSP00000396688.2	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:co4a_human(display_long)|uniprotkb:C4A(gene name)|psi-mi:C4A(display_short)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD2(gene name synonym)|uniprotkb:Acidic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807789|imex:IM-13779-1184	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:117""|efo:""Orphanet:169147""|efo:""Orphanet:300345""|efo:""Orphanet:536""|ensembl:ENSG00000206340.10(gene)|ensembl:ENSG00000227746.10(gene)|ensembl:ENSG00000244731.10(gene)|ensembl:ENST00000383325.8(transcript)|ensembl:ENST00000421274.7(transcript)|ensembl:ENST00000428956.7(transcript)|go:""GO:0001849""(complement component C1q complex binding)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0006956""(complement activation)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045087""(innate immune response)|go:""GO:0045202""(synapse)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:2000427""(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR047565|interpro:IPR048847|interpro:IPR050473|interpro:IPR054587|rcsb pdb:1HZF|rcsb pdb:5JPM|rcsb pdb:5JPN|rcsb pdb:5JTW|rcsb pdb:6YSQ|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977606|refseq:NP_001002029.3|refseq:NP_001239133.1|refseq:NP_009224.2|panther:PTHR11412(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nLlIFlW5RCngnXASkYPGREjA/1E9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:6F63C9DC585EE058|rigid:NUBSkcYeXjDijpZDsiZ1toVmQbo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI82	uniprotkb:P02462	intact:EBI-2807827|uniprotkb:A0A0G2RNX3	intact:EBI-2432478|uniprotkb:B1AM70|uniprotkb:A7E2W4|uniprotkb:Q1P9S9|uniprotkb:Q5VWF6|uniprotkb:Q86X41|uniprotkb:Q8NF88|uniprotkb:Q9NYC5|uniprotkb:F5H5K0|ensembl:ENSP00000364979.4	psi-mi:q5ni82_fratt(display_long)|uniprotkb:FTT_0199(locus name)	psi-mi:co4a1_human(display_long)|uniprotkb:COL4A1(gene name)|psi-mi:COL4A1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807824|imex:IM-13779-1191	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003023105.1	"ensembl:ENSG00000187498.17(gene)|ensembl:ENST00000375820.10(transcript)|go:""GO:0001569""(branching involved in blood vessel morphogenesis)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005587""(collagen type IV trimer)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007420""(brain development)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0038063""(collagen-activated tyrosine kinase receptor signaling pathway)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048514""(blood vessel morphogenesis)|go:""GO:0061304""(retinal blood vessel morphogenesis)|go:""GO:0061333""(renal tubule morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071711""(basement membrane organization)|interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036954|interpro:IPR050149|mint:P02462|rcsb pdb:1LI1|rcsb pdb:5NAX|rcsb pdb:5NAY|rcsb pdb:6MPX|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8948216|refseq:NP_001290039.1|refseq:NP_001836.3|efo:""Orphanet:36383""|efo:""Orphanet:477749""|efo:""Orphanet:481986""|efo:""Orphanet:73229""|efo:""Orphanet:75326""|efo:""Orphanet:899""|efo:""Orphanet:99810""|panther:PTHR24023(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E2qML/pquGepKxmBAyIk4GDo0kM177416	rogid:/U3Xsl1lPZnPBfd1cRVDqtuvVb49606	intact-crc:39A5B23A3A67E703|rigid:ut4xtNukj8ns4Ocky4y+lXGjjag	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NII1	uniprotkb:P02462	intact:EBI-2797156|uniprotkb:A0A0G2RN00	intact:EBI-2432478|uniprotkb:B1AM70|uniprotkb:A7E2W4|uniprotkb:Q1P9S9|uniprotkb:Q5VWF6|uniprotkb:Q86X41|uniprotkb:Q8NF88|uniprotkb:Q9NYC5|uniprotkb:F5H5K0|ensembl:ENSP00000364979.4	psi-mi:q5nii1_fratt(display_long)|uniprotkb:acnA(gene name)|psi-mi:acnA(display_short)|uniprotkb:FTT_0087(locus name)	psi-mi:co4a1_human(display_long)|uniprotkb:COL4A1(gene name)|psi-mi:COL4A1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807817|imex:IM-13779-1188	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR044137|refseq:YP_169161.1|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR018136|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|refseq:WP_003019815.1|interpro:IPR036008"	"ensembl:ENSG00000187498.17(gene)|ensembl:ENST00000375820.10(transcript)|go:""GO:0001569""(branching involved in blood vessel morphogenesis)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005587""(collagen type IV trimer)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007420""(brain development)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0038063""(collagen-activated tyrosine kinase receptor signaling pathway)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048514""(blood vessel morphogenesis)|go:""GO:0061304""(retinal blood vessel morphogenesis)|go:""GO:0061333""(renal tubule morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071711""(basement membrane organization)|interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036954|interpro:IPR050149|mint:P02462|rcsb pdb:1LI1|rcsb pdb:5NAX|rcsb pdb:5NAY|rcsb pdb:6MPX|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8948216|refseq:NP_001290039.1|refseq:NP_001836.3|efo:""Orphanet:36383""|efo:""Orphanet:477749""|efo:""Orphanet:481986""|efo:""Orphanet:73229""|efo:""Orphanet:75326""|efo:""Orphanet:899""|efo:""Orphanet:99810""|panther:PTHR24023(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FGVUBUKOHsDquKU0LqPkXCpRg+o177416	rogid:/U3Xsl1lPZnPBfd1cRVDqtuvVb49606	intact-crc:0C84B23A3A904A5E|rigid:kpnLR0GuC1lxTCLJ6l30XCNOrNI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08572	uniprotkb:Q5NIP6	intact:EBI-2432506|uniprotkb:Q14052|uniprotkb:Q548C3|uniprotkb:Q5VZA9|uniprotkb:Q66K23|ensembl:ENSP00000353654.5|ensembl:ENSP00000383027.4	intact:EBI-2796567	psi-mi:co4a2_human(display_long)|uniprotkb:COL4A2(gene name)|psi-mi:COL4A2(display_short)	psi-mi:gata_fratt(display_long)|uniprotkb:FTT_0020(locus name)|uniprotkb:gatA(gene name)|psi-mi:gatA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807810|imex:IM-13779-1190	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8948216|refseq:NP_001837.2|efo:""Orphanet:36383""|ensembl:ENSG00000134871.20(gene)|ensembl:ENST00000360467.7(transcript)|ensembl:ENST00000400163.8(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005587""(collagen type IV trimer)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0014823""(response to activity)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0038063""(collagen-activated tyrosine kinase receptor signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036954|interpro:IPR050149|mint:P08572|rcsb pdb:1LI1|rcsb pdb:5NAX|rcsb pdb:5NB2|rcsb pdb:6MPX|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|efo:""Orphanet:99810""|panther:PTHR24023(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0030956""(""glutamyl-tRNA(Gln) amidotransferase complex"")|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|interpro:IPR000120(Amidase signature enzyme)|interpro:IPR020556|interpro:IPR023631|interpro:IPR004412(""Glutamyl-tRNA(Gln) amidotransferase A subunit"")|refseq:YP_169096.1|refseq:WP_003022862.1|interpro:IPR036928"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2jSdn1hb9JtAPdSLo82KAbqdzr09606	rogid:PXaa59Zvn1xzo0G3HrDFgI8WSJg177416	intact-crc:91F048135F57D070|rigid:oe0jygMrDaLWgbcOJkoQCnddEWM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P02461	uniprotkb:Q5NFA1	intact:EBI-2431491|uniprotkb:P78429|uniprotkb:Q15112|uniprotkb:Q9UC90|uniprotkb:Q9UC91|uniprotkb:Q16403|uniprotkb:Q53S91|uniprotkb:Q541P8|uniprotkb:Q6LDB3|uniprotkb:Q6LDJ2|uniprotkb:Q6LDJ3|uniprotkb:Q7KZ56|uniprotkb:Q8N6U4|uniprotkb:Q9UC88|uniprotkb:Q9UC89|uniprotkb:D2JYH5|uniprotkb:R4N3C5|uniprotkb:V9GZI1|uniprotkb:D3DPH4|ensembl:ENSP00000304408.4	intact:EBI-2797066|uniprotkb:A0A0G2RM98	psi-mi:co3a1_human(display_long)|uniprotkb:COL3A1(gene name)|psi-mi:COL3A1(display_short)	psi-mi:q5nfa1_fratt(display_long)|uniprotkb:FTT_1339c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807834|imex:IM-13779-1189	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168542.18(gene)|ensembl:ENST00000304636.9(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001764""(neuron migration)|go:""GO:0001894""(tissue homeostasis)|go:""GO:0002020""(protease binding)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005586""(collagen type III trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007507""(heart development)|go:""GO:0009314""(response to radiation)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0021819""(layer formation in cerebral cortex)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030168""(platelet activation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0032905""(transforming growth factor beta1 production)|go:""GO:0034097""(response to cytokine)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0036022""(limb joint morphogenesis)|go:""GO:0042060""(wound healing)|go:""GO:0043588""(skin development)|go:""GO:0046332""(SMAD binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048565""(digestive tract development)|go:""GO:0050777""(negative regulation of immune response)|go:""GO:0060350""(endochondral bone morphogenesis)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:1990776""(response to angiotensin)|go:""GO:2001223""(negative regulation of neuron migration)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|mint:P02461|rcsb pdb:2V53|rcsb pdb:3DMW|rcsb pdb:4AE2|rcsb pdb:4AEJ|rcsb pdb:4AK3|rcsb pdb:4GYX|rcsb pdb:6FZV|rcsb pdb:6FZW|rcsb pdb:7WWR|rcsb pdb:7WWS|rcsb pdb:7XAN|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_000081.1|dip:DIP-57177N|efo:""Orphanet:231160""|efo:""Orphanet:2500""|efo:""Orphanet:286""|efo:""Orphanet:636941""|efo:""Orphanet:86""|panther:PTHR24023(orthology-group)"	"go:""GO:0016020""(membrane)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|refseq:YP_170291.1|interpro:IPR036513|interpro:IPR052706|refseq:WP_003022095.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mJwvNKDtUVF6OMwaeEO2xcjKYWE9606	rogid:6Zt8IB73d/bI77NTYHhVCWhbQ0U177416	intact-crc:4B3394F424A66E85|rigid:kLZwVEzzM8EKSw2qtadGKnvGJ+E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC2	uniprotkb:P02461	intact:EBI-2800919|uniprotkb:A0A0G2RP94	intact:EBI-2431491|uniprotkb:P78429|uniprotkb:Q15112|uniprotkb:Q9UC90|uniprotkb:Q9UC91|uniprotkb:Q16403|uniprotkb:Q53S91|uniprotkb:Q541P8|uniprotkb:Q6LDB3|uniprotkb:Q6LDJ2|uniprotkb:Q6LDJ3|uniprotkb:Q7KZ56|uniprotkb:Q8N6U4|uniprotkb:Q9UC88|uniprotkb:Q9UC89|uniprotkb:D2JYH5|uniprotkb:R4N3C5|uniprotkb:V9GZI1|uniprotkb:D3DPH4|ensembl:ENSP00000304408.4	psi-mi:q5nec2_fratt(display_long)|uniprotkb:pdpD1(gene name synonym)|uniprotkb:pdpD2(gene name)|psi-mi:pdpD2(display_short)|uniprotkb:FTT_1360c(locus name)|uniprotkb:FTT_1715c(locus name)	psi-mi:co3a1_human(display_long)|uniprotkb:COL3A1(gene name)|psi-mi:COL3A1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807841|imex:IM-13779-1194	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_170312.1|refseq:YP_170620.1|refseq:WP_003022155.1	"ensembl:ENSG00000168542.18(gene)|ensembl:ENST00000304636.9(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001764""(neuron migration)|go:""GO:0001894""(tissue homeostasis)|go:""GO:0002020""(protease binding)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005586""(collagen type III trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007507""(heart development)|go:""GO:0009314""(response to radiation)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0021819""(layer formation in cerebral cortex)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030168""(platelet activation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0032905""(transforming growth factor beta1 production)|go:""GO:0034097""(response to cytokine)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0036022""(limb joint morphogenesis)|go:""GO:0042060""(wound healing)|go:""GO:0043588""(skin development)|go:""GO:0046332""(SMAD binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048565""(digestive tract development)|go:""GO:0050777""(negative regulation of immune response)|go:""GO:0060350""(endochondral bone morphogenesis)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:1990776""(response to angiotensin)|go:""GO:2001223""(negative regulation of neuron migration)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|mint:P02461|rcsb pdb:2V53|rcsb pdb:3DMW|rcsb pdb:4AE2|rcsb pdb:4AEJ|rcsb pdb:4AK3|rcsb pdb:4GYX|rcsb pdb:6FZV|rcsb pdb:6FZW|rcsb pdb:7WWR|rcsb pdb:7WWS|rcsb pdb:7XAN|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_000081.1|dip:DIP-57177N|efo:""Orphanet:231160""|efo:""Orphanet:2500""|efo:""Orphanet:286""|efo:""Orphanet:636941""|efo:""Orphanet:86""|panther:PTHR24023(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6pCKkpYkHLAR+d8m78CBSN86v/8177416	rogid:mJwvNKDtUVF6OMwaeEO2xcjKYWE9606	intact-crc:13B607F42443D615|rigid:LLXuc37H9/e4Pl7B7ZsMdTGwxVE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3D6	uniprotkb:Q5NFY5	intact:EBI-2807872|uniprotkb:B3KUI7|uniprotkb:Q96GW5|uniprotkb:Q86SX8|uniprotkb:Q9H7G0|uniprotkb:Q86T08|uniprotkb:Q86TV5|uniprotkb:Q9H8Y9|uniprotkb:Q86SX9|uniprotkb:Q86SW3|uniprotkb:Q9H9W6|ensembl:ENSP00000404343.2|ensembl:ENSP00000427953.1|ensembl:ENSP00000428974.1|ensembl:ENSP00000429655.1	intact:EBI-2799103|uniprotkb:A0A0G2RM96	psi-mi:glucm_human(display_long)|uniprotkb:DGLUCY(gene name)|psi-mi:DGLUCY(display_short)|uniprotkb:C14orf159(gene name synonym)|uniprotkb:UNQ2439/PRO5000(orf name)	psi-mi:q5nfy5_fratt(display_long)|uniprotkb:FTT_1078c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807869|imex:IM-13779-1196	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273399.1|refseq:NP_001273400.1|refseq:NP_001273401.1|refseq:NP_001273402.1|refseq:NP_001095836.1|refseq:NP_001095837.1|refseq:NP_001095838.1|refseq:NP_001095839.1|refseq:NP_079228.4|ensembl:ENSG00000133943.21(gene)|ensembl:ENST00000428926.6(transcript)|ensembl:ENST00000522322.5(transcript)|ensembl:ENST00000523771.5(transcript)|ensembl:ENST00000523816.5(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006536""(glutamate metabolic process)|go:""GO:0047820""(D-glutamate cyclase activity)|interpro:IPR009906(Protein of unknown function DUF1445)|interpro:IPR017135(Uncharacterised conserved protein UPF0317, mitochondria)|interpro:IPR025504|interpro:IPR038021|panther:PTHR32022(orthology-group)"	refseq:WP_003021212.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BySeqCOzB6a3NNzdlvpJJM3eEzo9606	rogid:ZCh5UU3BrwGnp/Qxno/CBNEc368177416	intact-crc:A88829F2C9E48579|rigid:w2kQarUfrp9UJd8/DiEkkEBzgHQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08123	uniprotkb:Q5NHY6	intact:EBI-983038|uniprotkb:P02464|uniprotkb:Q13897|uniprotkb:Q13997|uniprotkb:Q7Z5S6|uniprotkb:Q9UEB6|uniprotkb:Q9UEF9|uniprotkb:Q9UM83|uniprotkb:Q9UMI1|uniprotkb:Q9UML5|uniprotkb:Q9UMM6|uniprotkb:Q9UPH0|uniprotkb:Q13998|uniprotkb:Q14038|uniprotkb:Q14057|uniprotkb:Q15177|uniprotkb:Q15947|uniprotkb:Q16480|uniprotkb:Q16511|ensembl:ENSP00000297268.6	intact:EBI-2796153	psi-mi:co1a2_human(display_long)|uniprotkb:Alpha-2 type I collagen(gene name synonym)|uniprotkb:COL1A2(gene name)|psi-mi:COL1A2(display_short)	psi-mi:sye_fratt(display_long)|uniprotkb:gltX(gene name)|psi-mi:gltX(display_short)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0307(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807848|imex:IM-13779-1192	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164692.19(gene)|ensembl:ENST00000297268.11(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001568""(blood vessel development)|go:""GO:0002020""(protease binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005584""(collagen type I trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030282""(bone mineralization)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032963""(collagen metabolic process)|go:""GO:0042476""(odontogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0046332""(SMAD binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070208""(protein heterotrimerization)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0085029""(extracellular matrix assembly)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|mint:P08123|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:6JEC|reactome:R-HSA-114604|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2173796|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-430116|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-8874081|reactome:R-HSA-8948216|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000080.2|dip:DIP-36079N|efo:""Orphanet:1899""|efo:""Orphanet:216796""|efo:""Orphanet:216804""|efo:""Orphanet:216812""|efo:""Orphanet:216820""|efo:""Orphanet:230851""|efo:""Orphanet:230857""|efo:""Orphanet:314029""|panther:PTHR24023(orthology-group)"	"refseq:YP_169356.1|interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004527(Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020058|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:WP_003021625.1|interpro:IPR033910|interpro:IPR045462|interpro:IPR049940|go:""GO:0000049""(tRNA binding)|go:""GO:0004818""(glutamate-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006424""(glutamyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:vRxr0tOWziIyQf9or1gC6sDlN8I9606	rogid:6DvyR/b9UNDoFX+nMfvtqGvLXt4177416	intact-crc:9241F0D92856F2AF|rigid:0WJKyGdQsYkIXh/TSqUW6buc7o4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A5YKK6	uniprotkb:Q5NGF1	intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949.5	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name)	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807862|imex:IM-13779-1193	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:556955""|ensembl:ENSG00000125107.19(gene)|ensembl:ENST00000317147.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000288""(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:0000289""(""nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0000932""(P-body)|go:""GO:0001829""(trophectodermal cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0010606""(positive regulation of cytoplasmic mRNA processing body assembly)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030014""(CCR4-NOT complex)|go:""GO:0030015""(CCR4-NOT core complex)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0033147""(negative regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0048387""(negative regulation of retinoic acid receptor signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0061014""(positive regulation of mRNA catabolic process)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:2000036""(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|interpro:IPR055104|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|refseq:NP_996882.1|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|rcsb pdb:7VOI|rcsb pdb:8BFI|rcsb pdb:8FY3|reactome:R-HSA-429947|reactome:R-HSA-6804115|reactome:R-HSA-9820841|refseq:NP_001252541.1|refseq:NP_057368.3|dip:DIP-44954N|panther:PTHR13162(orthology-group)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	intact-crc:4445352799C82D1E|rigid:BcsjApf3fgamy1kKwveU5+njFJ4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P02452	uniprotkb:Q5NFY4	intact:EBI-982999|uniprotkb:O76045|uniprotkb:P78441|uniprotkb:Q13896|uniprotkb:Q13902|uniprotkb:Q13903|uniprotkb:Q14037|uniprotkb:Q14992|uniprotkb:Q15176|uniprotkb:Q15201|uniprotkb:Q16050|uniprotkb:Q59F64|uniprotkb:Q7KZ30|uniprotkb:Q7KZ34|uniprotkb:Q8IVI5|uniprotkb:Q8N473|uniprotkb:Q9UML6|uniprotkb:Q9UMM7|ensembl:ENSP00000225964.6	intact:EBI-2799645|uniprotkb:A0A0G2RQ80	psi-mi:co1a1_human(display_long)|uniprotkb:Alpha-1 type I collagen(gene name synonym)|uniprotkb:COL1A1(gene name)|psi-mi:COL1A1(display_short)	psi-mi:q5nfy4_fratt(display_long)|uniprotkb:FTT_1079c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807855|imex:IM-13779-1195	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108821.14(gene)|ensembl:ENST00000225964.10(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001503""(ossification)|go:""GO:0001568""(blood vessel development)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001957""(intramembranous ossification)|go:""GO:0001958""(endochondral ossification)|go:""GO:0002020""(protease binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005584""(collagen type I trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007601""(visual perception)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0015031""(protein transport)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030141""(secretory granule)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032355""(response to estradiol)|go:""GO:0032868""(response to insulin)|go:""GO:0032964""(collagen biosynthetic process)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034505""(tooth mineralization)|go:""GO:0038063""(collagen-activated tyrosine kinase receptor signaling pathway)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042802""(identical protein binding)|go:""GO:0043588""(skin development)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0048706""(embryonic skeletal system development)|go:""GO:0051591""(response to cAMP)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060346""(bone trabecula formation)|go:""GO:0060351""(cartilage development involved in endochondral bone morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071306""(cellular response to vitamin E)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:1902618""(cellular response to fluoride)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|mint:P02452|rcsb pdb:1Q7D|rcsb pdb:2LLP|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:5CVB|rcsb pdb:5K31|rcsb pdb:5OU8|rcsb pdb:5OU9|rcsb pdb:7E7B|rcsb pdb:7E7D|reactome:R-HSA-114604|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-8874081|reactome:R-HSA-8940973|reactome:R-HSA-8948216|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000079.2|dip:DIP-36077N|efo:""Orphanet:31112""|efo:""Orphanet:314029""|efo:""Orphanet:287""|efo:""Orphanet:1310""|efo:""Orphanet:1899""|efo:""Orphanet:216796""|efo:""Orphanet:216804""|efo:""Orphanet:216812""|efo:""Orphanet:216820""|efo:""Orphanet:230857""|panther:PTHR24023(orthology-group)"	refseq:YP_170058.1|refseq:WP_003026641.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7tMYoZQIXMoLjRyYc/uiKYKCifY9606	rogid:v1mSgBDe90RxW8uHIi9a67zCxJs177416	intact-crc:2F04F12C24AEB3BA|rigid:l2ZpZ9PdqjJxdAk9CifKpdQD3QY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75503	uniprotkb:Q5NF50	intact:EBI-1043514|uniprotkb:B3KQK7|ensembl:ENSP00000366673.5|ensembl:ENSP00000490181.2	intact:EBI-2799423|uniprotkb:A0A0G2RN72	psi-mi:cln5_human(display_long)|uniprotkb:CLN5(gene name)|psi-mi:CLN5(display_short)|uniprotkb:Ceroid-lipofuscinosis neuronal protein 5(gene name synonym)|uniprotkb:Palmitoyl protein thioesterase CLN5(gene name synonym)|uniprotkb:S-depalmitoylase CLN5(gene name synonym)|uniprotkb:BMPS(gene name synonym)	psi-mi:q5nf50_fratt(display_long)|uniprotkb:Exonuclease V subunit RecC(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecC(gene name synonym)|uniprotkb:recC(gene name)|psi-mi:recC(display_short)|uniprotkb:FTT_1397c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807897|imex:IM-13779-1199	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:228360""|ensembl:ENSG00000102805.16(gene)|ensembl:ENST00000377453.9(transcript)|ensembl:ENST00000636183.2(transcript)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005775""(vacuolar lumen)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006465""(signal peptide processing)|go:""GO:0007040""(lysosome organization)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0007420""(brain development)|go:""GO:0007601""(visual perception)|go:""GO:0016020""(membrane)|go:""GO:0016798""(hydrolase activity, acting on glycosyl bonds)|go:""GO:0022008""(neurogenesis)|go:""GO:0030163""(protein catabolic process)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042551""(neuron maturation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0052816""(long-chain fatty acyl-CoA hydrolase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070085""(glycosylation)|go:""GO:0160121""(""bis(monoacylglycero)phosphate synthase activity"")|go:""GO:1904426""(positive regulation of GTP binding)|interpro:IPR026138|mint:O75503|rcsb pdb:6R99|refseq:NP_006484.1|panther:PTHR15380(orthology-group)"	"interpro:IPR006697(Exodeoxyribonuclease V, RecC subunit)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|refseq:YP_170342.1|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|refseq:WP_003022201.1|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR041500"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YBJqxznEkJjC7Rdm95cpHHBPuE49606	rogid:dix8s5jOlPbCloD4EjJhnk5rYr4177416	intact-crc:BC1FE7301E872E8A|rigid:o6+aPRhTqOdjAzO7bfa9xyqkYng	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:Q8NDC0	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-741424|uniprotkb:Q96BG5|uniprotkb:B2RDD8|ensembl:ENSP00000378851.3	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:missl_human(display_long)|uniprotkb:C14orf32(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 1-interacting protein 1-like(gene name synonym)|uniprotkb:MAPK1IP1L(gene name)|psi-mi:MAPK1IP1L(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807890|imex:IM-13779-1197	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	refseq:NP_653179.1|ensembl:ENSG00000168175.16(gene)|ensembl:ENST00000395468.9(transcript)|interpro:IPR031653|panther:PTHR35973(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:CX220vB2TjggPEso5CHNUVzl79g9606	intact-crc:F9AC38A6BAC83998|rigid:wgQqCd8a7tUedZ7xTfo3nDHHnms	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI40	uniprotkb:P51790	intact:EBI-2796048	intact:EBI-349797|uniprotkb:O14918|uniprotkb:Q86Z21|uniprotkb:D3DP34|uniprotkb:B7Z932|ensembl:ENSP00000424603.1|uniprotkb:B9EGJ9|uniprotkb:E9PB97	psi-mi:q5ni40_fratt(display_long)|uniprotkb:ppdK(gene name)|psi-mi:ppdK(display_short)|uniprotkb:FTT_0250(locus name)	psi-mi:clcn3_human(display_long)|uniprotkb:CLCN3(gene name)|psi-mi:CLCN3(display_short)|uniprotkb:Chloride transporter ClC-3(gene name synonym)|uniprotkb:Chloride channel protein 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807904|imex:IM-13779-1198	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169302.1|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR018274|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR023151|interpro:IPR002192(Pyruvate phosphate dikinase, PEP/pyruvate-binding)|interpro:IPR010121(Pyruvate, phosphate dikinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR040442|interpro:IPR036637|go:""GO:0005524""(ATP binding)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0050242""(pyruvate, phosphate dikinase activity)"	"ensembl:ENSG00000109572.16(gene)|ensembl:ENST00000513761.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005247""(voltage-gated chloride channel activity)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006885""(regulation of pH)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0012506""(vesicle membrane)|go:""GO:0015297""(antiporter activity)|go:""GO:0016020""(membrane)|go:""GO:0030141""(secretory granule)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0035249""(synaptic transmission, glutamatergic)|go:""GO:0042581""(specific granule)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043679""(axon terminus)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045494""(photoreceptor cell maintenance)|go:""GO:0045794""(negative regulation of cell volume)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0051932""(synaptic transmission, GABAergic)|go:""GO:0055037""(recycling endosome)|go:""GO:0072320""(volume-sensitive chloride channel activity)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:1902476""(chloride transmembrane transport)|go:""GO:1903428""(positive regulation of reactive oxygen species biosynthetic process)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002245(Chloride channel CLC-3)|interpro:IPR014743(Chloride channel, core)|interpro:IPR046342|reactome:R-HSA-2672351|refseq:NP_001230301.1|refseq:NP_001230303.1|refseq:NP_001820.2|refseq:NP_776297.2|panther:PTHR45711(orthology-group)|efo:""Orphanet:528084"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lPu2TgwGa8adgnlyO6g7UzHr7Ns177416	rogid:DC0lX5brqRB+qboQK3eBNYF6wc89606	intact-crc:EA3FC03A935833F0|rigid:TiXsRLJQq/i1g2Qiiu2OinCAIcU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFP9	uniprotkb:Q14CX7	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	intact:EBI-1048503|uniprotkb:A0JLU7|uniprotkb:Q6MZH1|uniprotkb:Q7Z4N6|uniprotkb:Q9H911|ensembl:ENSP00000261745.4	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	psi-mi:naa25_human(display_long)|uniprotkb:p120(gene name synonym)|uniprotkb:NAA25(gene name)|psi-mi:NAA25(display_short)|uniprotkb:C12orf30(gene name synonym)|uniprotkb:Mitochondrial distribution and morphology protein 20(gene name synonym)|uniprotkb:NAP1(gene name synonym)|uniprotkb:N-terminal acetyltransferase B complex subunit NAA25(gene name synonym)|uniprotkb:MDM20(gene name synonym)|uniprotkb:N-terminal acetyltransferase B complex subunit MDM20(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807935|imex:IM-13779-1201	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	"refseq:NP_079229.2|ensembl:ENSG00000111300.10(gene)|ensembl:ENST00000261745.9(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0010698""(acetyltransferase activator activity)|go:""GO:0031416""(NatB complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019183|rcsb pdb:6VP9|rcsb pdb:7STX|rcsb pdb:8G0L|dip:DIP-50826N|panther:PTHR22767(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	rogid:1L8cWTeurptH6LtfpKx0R6hs02M9606	intact-crc:149E76A4A097A098|rigid:J/0DNvJfSmHJmMR9Ry78n8Q9BZI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14CX7	uniprotkb:Q5NFJ3	intact:EBI-1048503|uniprotkb:A0JLU7|uniprotkb:Q6MZH1|uniprotkb:Q7Z4N6|uniprotkb:Q9H911|ensembl:ENSP00000261745.4	intact:EBI-2807437	psi-mi:naa25_human(display_long)|uniprotkb:p120(gene name synonym)|uniprotkb:NAA25(gene name)|psi-mi:NAA25(display_short)|uniprotkb:C12orf30(gene name synonym)|uniprotkb:Mitochondrial distribution and morphology protein 20(gene name synonym)|uniprotkb:NAP1(gene name synonym)|uniprotkb:N-terminal acetyltransferase B complex subunit NAA25(gene name synonym)|uniprotkb:MDM20(gene name synonym)|uniprotkb:N-terminal acetyltransferase B complex subunit MDM20(gene name synonym)	psi-mi:glya_fratt(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:FTT_1241(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807942|imex:IM-13779-1204	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079229.2|ensembl:ENSG00000111300.10(gene)|ensembl:ENST00000261745.9(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0010698""(acetyltransferase activator activity)|go:""GO:0031416""(NatB complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019183|rcsb pdb:6VP9|rcsb pdb:7STX|rcsb pdb:8G0L|dip:DIP-50826N|panther:PTHR22767(orthology-group)"	"interpro:IPR049943|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR019798|refseq:YP_170199.1|go:""GO:0004372""(glycine hydroxymethyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0019264""(glycine biosynthetic process from serine)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0035999""(tetrahydrofolate interconversion)|interpro:IPR039429|refseq:WP_003021543.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:1L8cWTeurptH6LtfpKx0R6hs02M9606	rogid:YGV3lD5dnE8X8rx9qJdzXtxEdhM177416	intact-crc:A8E476A4A2CE3453|rigid:ApbvzFUgA8XrDE/0811yUQ1jJ+E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHY8	uniprotkb:Q8N1N0	intact:EBI-2807911|uniprotkb:A0A0G2RMB2	intact:EBI-948238|uniprotkb:A4QPA5|ensembl:ENSP00000272367.2	psi-mi:q5nhy8_fratt(display_long)|uniprotkb:FTT_0305(locus name)	psi-mi:clc4f_human(display_long)|uniprotkb:C-type lectin superfamily member 13(gene name synonym)|uniprotkb:CLEC4F(gene name)|psi-mi:CLEC4F(display_short)|uniprotkb:CLECSF13(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807914|imex:IM-13779-1202	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020476|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:YP_169354.1|go:""GO:0016787""(hydrolase activity)|refseq:WP_003021630.1"	"refseq:NP_775806.2|refseq:NP_001308237.1|ensembl:ENSG00000152672.8(gene)|ensembl:ENST00000272367.7(transcript)|go:""GO:0006897""(endocytosis)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0038187""(pattern recognition receptor activity)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033989|interpro:IPR050111|panther:PTHR22802(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:czDXHeMrvjw4R9/10u5xMSXXA4M177416	rogid:tFiGPJYQdGlBXwZQrCz/pRDO4uQ9606	intact-crc:9B32E9FD56BBD372|rigid:Sg37ylbAciS1guXErpTPVqlu+s4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75122	uniprotkb:Q5NHN7	intact:EBI-913524|uniprotkb:Q7L8F6|uniprotkb:Q8N6R6|uniprotkb:Q9BQT3|uniprotkb:Q9BQT4|uniprotkb:Q9H7A3|uniprotkb:Q9NSZ2|ensembl:ENSP00000417518.2|intact:EBI-2514712|uniprotkb:B2RTR1|uniprotkb:F5H604|intact:EBI-10967478	intact:EBI-2802363|uniprotkb:A0A0G2RLZ9	psi-mi:clap2_human(display_long)|uniprotkb:CLASP2(gene name)|psi-mi:CLASP2(display_short)|uniprotkb:KIAA0627(gene name synonym)|uniprotkb:Cytoplasmic linker-associated protein 2(gene name synonym)|uniprotkb:Protein Orbit homolog 2(gene name synonym)	psi-mi:q5nhn7_fratt(display_long)|uniprotkb:gcvP2(gene name)|psi-mi:gcvP2(display_short)|uniprotkb:FTT_0410(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807921|imex:IM-13779-1200	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193973.1|refseq:NP_055912.2|ensembl:ENSG00000163539.19(gene)|ensembl:ENST00000480013.6(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000776""(kinetochore)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005828""(kinetochore microtubule)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005876""(spindle microtubule)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006903""(vesicle targeting)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007026""(negative regulation of microtubule depolymerization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0008017""(microtubule binding)|go:""GO:0010458""(exit from mitosis)|go:""GO:0010470""(regulation of gastrulation)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0010717""(regulation of epithelial to mesenchymal transition)|go:""GO:0016020""(membrane)|go:""GO:0030516""(regulation of axon extension)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0031110""(regulation of microtubule polymerization or depolymerization)|go:""GO:0031113""(regulation of microtubule polymerization)|go:""GO:0031252""(cell leading edge)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032886""(regulation of microtubule-based process)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0035791""(platelet-derived growth factor receptor-beta signaling pathway)|go:""GO:0040001""(establishment of mitotic spindle localization)|go:""GO:0044295""(axonal growth cone)|go:""GO:0045180""(basal cortex)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051301""(cell division)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0051895""(negative regulation of focal adhesion assembly)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090091""(positive regulation of extracellular matrix disassembly)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099187""(presynaptic cytoskeleton organization)|go:""GO:1903690""(negative regulation of wound healing, spreading of epidermal cells)|go:""GO:1903754""(cortical microtubule plus-end)|go:""GO:1904261""(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024395|interpro:IPR034085|mint:O75122|rcsb pdb:3WOY|rcsb pdb:5NR4|rcsb pdb:8WHH|rcsb pdb:8WHI|rcsb pdb:8WHJ|rcsb pdb:8WHK|rcsb pdb:8WHL|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-428890|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36804N|panther:PTHR21567(orthology-group)"	"interpro:IPR020581|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:YP_169455.1|refseq:WP_011242235.1|go:""GO:0004375""(""glycine dehydrogenase (decarboxylating) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0016594""(glycine binding)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR049315|interpro:IPR049316"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/13	rogid:FNIEvRFPqFi6NPFLsVHlKvfkN9w9606	rogid:PrvVzFJYuRfdefUo4kpPUAO8pgg177416	intact-crc:8AEBBCB11DECCD66|rigid:B7ArqJJbeOEhENVWihpXUOyfzDw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCM1	uniprotkb:Q5NF31	intact:EBI-308368|uniprotkb:Q4KN17|uniprotkb:Q9NVL6|uniprotkb:Q9NWP9|uniprotkb:B2RTU5|ensembl:ENSP00000310338.4	intact:EBI-2801218|uniprotkb:A0A0G2RNH8	psi-mi:resf1_human(display_long)|uniprotkb:RESF1(gene name)|psi-mi:RESF1(display_short)|uniprotkb:C12orf35(gene name synonym)|uniprotkb:KIAA1551(gene name synonym)	psi-mi:q5nf31_fratt(display_long)|uniprotkb:nusB(gene name)|psi-mi:nusB(display_short)|uniprotkb:Antitermination factor NusB(gene name synonym)|uniprotkb:FTT_1418c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807928|imex:IM-13779-1203	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060639.3|ensembl:ENSG00000174718.12(gene)|ensembl:ENST00000312561.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0042393""(histone binding)|go:""GO:0141005""(transposable element silencing by heterochromatin formation)|go:""GO:1990226""(histone methyltransferase binding)|interpro:IPR027866|mint:Q9HCM1|refseq:XP_005253462.1|refseq:XP_011519024.1|refseq:XP_016875039.1|dip:DIP-37599N|panther:PTHR21604(orthology-group)"	"interpro:IPR011605(NusB antitermination factor)|interpro:IPR006027(NusB/RsmB/TIM44)|refseq:YP_170361.1|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|refseq:WP_003022234.1|interpro:IPR035926"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JZhTz9sIotvCEoYh1IrFDhM5KzE9606	rogid:qmu3F+Cf/c260g8lVqz2f62Wpp0177416	intact-crc:ACB63C0698E64768|rigid:dwlVhOElUmtf3Q2F0vR+uy36EpQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEB0	uniprotkb:Q9NX76	intact:EBI-2807952	intact:EBI-1054315|uniprotkb:Q6IAC4|ensembl:ENSP00000205636.3	psi-mi:obg_fratt(display_long)|uniprotkb:obg(gene name)|psi-mi:obg(display_short)|uniprotkb:GTP-binding protein Obg(gene name synonym)|uniprotkb:FTT_1731c(locus name)	psi-mi:cklf6_human(display_long)|uniprotkb:Chemokine-like factor superfamily member 6(gene name synonym)|uniprotkb:CMTM6(gene name)|psi-mi:CMTM6(display_short)|uniprotkb:CKLFSF6(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807964|imex:IM-13779-1205	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031167|interpro:IPR014100(GTP-binding protein Obg/CgtA)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006169(GTP1/OBG subdomain)|refseq:YP_170632.1|interpro:IPR027417|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0042254""(ribosome biogenesis)|refseq:WP_003022710.1|interpro:IPR036726|interpro:IPR045086"	"refseq:NP_060271.1|ensembl:ENSG00000091317.8(gene)|ensembl:ENST00000205636.4(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0055038""(recycling endosome membrane)|interpro:IPR008253(Marvel)|interpro:IPR050578|mint:Q9NX76|reactome:R-HSA-6798695|panther:PTHR22776(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2rn9b6uzZS8FpnM9+w641gLA5DQ177416	rogid:OrVBhhmdJZSWGfyJc/eYUYNtdYE9606	intact-crc:E9A5B73083537034|rigid:4LX8HSMrvBLi6T98xqC/zX4jyH0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14008	uniprotkb:Q5NHZ0	intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768.1	intact:EBI-2797492|uniprotkb:A0A0G2RNH9	psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym)	psi-mi:q5nhz0_fratt(display_long)|uniprotkb:lldD1(gene name)|psi-mi:lldD1(display_short)|uniprotkb:FTT_0303c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807971|imex:IM-13779-1208	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216.15(gene)|ensembl:ENST00000529230.6(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000922""(spindle pole)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007019""(microtubule depolymerization)|go:""GO:0007051""(spindle organization)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007098""(centrosome cycle)|go:""GO:0008017""(microtubule binding)|go:""GO:0016020""(membrane)|go:""GO:0030951""(establishment or maintenance of microtubule cytoskeleton polarity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0050658""(RNA transport)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0051298""(centrosome duplication)|go:""GO:0051301""(cell division)|go:""GO:0061863""(microtubule plus end polymerase)|go:""GO:0090063""(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|interpro:IPR045110|interpro:IPR048491|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|panther:PTHR12609(orthology-group)"	"go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0004460""(""L-lactate dehydrogenase (cytochrome) activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0009060""(aerobic respiration)|go:""GO:0010181""(FMN binding)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR012133(Alpha-hydroxy acid dehydrogenase, FMN-dependent)|interpro:IPR000262(FMN-dependent alpha-hydroxy acid dehydrogenase)|interpro:IPR008259(FMN-dependent alpha-hydroxy acid dehydrogenase, active site)|refseq:YP_169352.1|refseq:WP_003014268.1|interpro:IPR037396"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606	rogid:y9b4dmq9ggvJh1XsJVqfxVBq9OQ177416	intact-crc:ED6DB41F46F5A039|rigid:Z59xjzrmfZTsPq9V031Se1sU6Yk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEB0	uniprotkb:Q96FZ5	intact:EBI-2807952	intact:EBI-2807956|uniprotkb:Q5VLK1|ensembl:ENSP00000335605.5	psi-mi:obg_fratt(display_long)|uniprotkb:obg(gene name)|psi-mi:obg(display_short)|uniprotkb:GTP-binding protein Obg(gene name synonym)|uniprotkb:FTT_1731c(locus name)	psi-mi:cklf7_human(display_long)|uniprotkb:CMTM7(gene name)|psi-mi:CMTM7(display_short)|uniprotkb:CKLFSF7(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807949|imex:IM-13779-1207	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031167|interpro:IPR014100(GTP-binding protein Obg/CgtA)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006169(GTP1/OBG subdomain)|refseq:YP_170632.1|interpro:IPR027417|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0042254""(ribosome biogenesis)|refseq:WP_003022710.1|interpro:IPR036726|interpro:IPR045086"	"refseq:NP_612419.1|refseq:NP_852137.1|ensembl:ENSG00000153551.14(gene)|ensembl:ENST00000334983.10(transcript)|go:""GO:0002337""(B-1a B cell differentiation)|go:""GO:0005125""(cytokine activity)|go:""GO:0005615""(extracellular space)|go:""GO:0006935""(chemotaxis)|go:""GO:0016020""(membrane)|interpro:IPR008253(Marvel)|interpro:IPR050578|panther:PTHR22776(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2rn9b6uzZS8FpnM9+w641gLA5DQ177416	rogid:X8yUD5JSiCs5/pva6hNcj0bY/JI9606	intact-crc:D32092CD2E31145A|rigid:CspjDDxZRBsS1qSbkHp8LWHOc88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI90	uniprotkb:Q6IPW1	intact:EBI-2796997|uniprotkb:A0A0G2RNC0	intact:EBI-2807981|uniprotkb:Q6IAD3|uniprotkb:Q9NXX1|ensembl:ENSP00000492536.1	psi-mi:q5ni90_fratt(display_long)|uniprotkb:prfB(gene name)|psi-mi:prfB(display_short)|uniprotkb:FTT_0191(locus name)	psi-mi:ck071_human(display_long)|uniprotkb:C11orf71(gene name)|psi-mi:C11orf71(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807978|imex:IM-13779-1206	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004374(Peptide chain release factor 2)|refseq:YP_169252.1|go:""GO:0005737""(cytoplasm)|go:""GO:0016149""(translation release factor activity, codon specific)|interpro:IPR045853"	refseq:NP_061894.2|refseq:NP_001258491.1|ensembl:ENSG00000180425.11(gene)|ensembl:ENST00000623205.2(transcript)|interpro:IPR031487|panther:PTHR16445(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xfYbStHp/nzMNqFfoH4i6+wOWBI177416	rogid:CV4MGwJ1kaz5eelQcqLpogQ8u6Y9606	intact-crc:FDB33A4C0479B186|rigid:5jz5dBJ3u84OedcGmLWzRUmhFlU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI33	uniprotkb:Q9H330	intact:EBI-2800112|uniprotkb:A0A0G2RMA5	intact:EBI-2808027|uniprotkb:Q6ZME3|uniprotkb:Q8NDJ5|uniprotkb:Q5SS43|uniprotkb:Q96CG6|uniprotkb:Q5JTQ5|uniprotkb:B4DSW7|ensembl:ENSP00000363714.3	psi-mi:q5ni33_fratt(display_long)|uniprotkb:FTT_0257(locus name)	psi-mi:tm245_human(display_long)|uniprotkb:TMEM245(gene name)|psi-mi:TMEM245(display_short)|uniprotkb:C9orf5(gene name synonym)|uniprotkb:Protein CG-2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808024|imex:IM-13779-1210	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169309.1|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0006402""(mRNA catabolic process)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:WP_003021737.1|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR036388|interpro:IPR050180"	"refseq:NP_114401.2|ensembl:ENSG00000106771.13(gene)|ensembl:ENST00000374586.8(transcript)|go:""GO:0016020""(membrane)|interpro:IPR002549(Protein of unknown function UPF0118)|mint:Q9H330|panther:PTHR21716(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:T86jKHSo3mAW/ak8vzq3vAvG0j0177416	rogid:Jcvjmk2NsXpSo+jO6vljOl01/7U9606	intact-crc:FB521D63063535D6|rigid:jyiV1IGT6UT3ffDwbv1FK22vpRE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFV6	uniprotkb:Q5VYM1	intact:EBI-2797055|uniprotkb:A0A0G2RM43	intact:EBI-2808010|uniprotkb:Q86XC6|uniprotkb:Q9UF74|uniprotkb:A6NLE6|uniprotkb:E9PB26|ensembl:ENSP00000308279.5|intact:EBI-28984117	psi-mi:q5nfv6_fratt(display_long)|uniprotkb:rpoH(gene name)|psi-mi:rpoH(display_short)|uniprotkb:RNA polymerase sigma-32 factor(gene name synonym)|uniprotkb:FTT_1112c(locus name)	psi-mi:s31g1_human(display_long)|uniprotkb:SPATA31G1(gene name)|psi-mi:SPATA31G1(display_short)|uniprotkb:C9orf131(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808017|imex:IM-13779-1212	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0009408""(response to heat)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0016987""(sigma factor activity)|refseq:YP_170086.1|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012759(RNA polymerase sigma factor RpoH, proteobacteria)|refseq:WP_003021274.1|interpro:IPR050813"	refseq:NP_001035500.1|refseq:NP_001274320.1|refseq:NP_001035501.1|refseq:NP_001035502.1|refseq:NP_976044.2|ensembl:ENSG00000174038.13(gene)|ensembl:ENST00000312292.6(transcript)|interpro:IPR026677|panther:PTHR21777(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TUiRpVCoti/MNhIPmxh1x7nUv4Q177416	rogid:GrMZZ6WP8G8J2RExYp6wJsfTbpQ9606	intact-crc:771BFABBF935844C|rigid:EP+f7UzAWaioeU3Tjh0CK/QwlgQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86X95	uniprotkb:Q5NF29	intact:EBI-627102|uniprotkb:A6NFI6|uniprotkb:A8K8M4|uniprotkb:O95367|uniprotkb:Q12804|uniprotkb:Q4G1B9|uniprotkb:Q6PJI4|uniprotkb:Q8IWI2|ensembl:ENSP00000339723.3	intact:EBI-2799464|uniprotkb:A0A0G2RM05	psi-mi:cir1_human(display_long)|uniprotkb:CIR(gene name synonym)|uniprotkb:CBF1-interacting corepressor(gene name synonym)|uniprotkb:Recepin(gene name synonym)|uniprotkb:CIR1(gene name)|psi-mi:CIR1(display_short)	psi-mi:q5nf29_fratt(display_long)|uniprotkb:FTT_1420(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808003|imex:IM-13779-1209	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004873.3|ensembl:ENSG00000138433.16(gene)|ensembl:ENST00000342016.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0019901""(protein kinase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR019339|interpro:IPR040014|mint:Q86X95|rcsb pdb:6ZYM|rcsb pdb:8I0W|panther:PTHR13151(orthology-group)"	refseq:YP_170363.1|refseq:WP_003022236.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DMnBG746eQpvLsf9D+lgeUKnni09606	rogid:9mgAlzt6rxc4WD6OJAXEfdkNiOY177416	intact-crc:8F724C92266295B6|rigid:DAZLQ6jer/pqlKAfCv2CwkLiz+k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NER2	uniprotkb:Q8N8R7	intact:EBI-2806544|uniprotkb:A0A0G2RNI1	intact:EBI-2807994|uniprotkb:Q5HYH9|ensembl:ENSP00000282032.3	psi-mi:q5ner2_fratt(display_long)|uniprotkb:lepB(gene name)|psi-mi:lepB(display_short)|uniprotkb:FTT_1556c(locus name)	psi-mi:al14e_human(display_long)|uniprotkb:ARL14EP(gene name)|psi-mi:ARL14EP(display_short)|uniprotkb:ARF7 effector protein(gene name synonym)|uniprotkb:ARF7EP(gene name synonym)|uniprotkb:C11orf46(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2807991|imex:IM-13779-1211	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000223(Peptidase S26A, signal peptidase I)|interpro:IPR019758|interpro:IPR019757|interpro:IPR019533|refseq:YP_170480.1|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006465""(signal peptide processing)|go:""GO:0016020""(membrane)|refseq:WP_003022453.1|interpro:IPR036286"	"refseq:NP_689529.1|ensembl:ENSG00000152219.6(gene)|ensembl:ENST00000282032.4(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR029264|rcsb pdb:8HFP|panther:PTHR46536(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0gRosROSex/pqXQY08vJ6+/PfJw177416	rogid:i4NYCAjZ8uvzr0oZqlIbnaOq7n49606	intact-crc:2DE6108447B5997C|rigid:Lq33dIUC1WMeGxeryOoDYAyNoZ0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHS4	uniprotkb:Q7LBR1	intact:EBI-2798955|uniprotkb:A0A0G2RPB0	intact:EBI-2118090|uniprotkb:Q96E89|uniprotkb:Q9HD41|ensembl:ENSP00000432279.1	psi-mi:q5nhs4_fratt(display_long)|uniprotkb:Folylpolyglutamate synthetase(gene name synonym)|uniprotkb:Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase(gene name synonym)|uniprotkb:folC(gene name)|psi-mi:folC(display_short)|uniprotkb:Tetrahydrofolylpolyglutamate synthase(gene name synonym)|uniprotkb:FTT_0371c(locus name)	psi-mi:chm1b_human(display_long)|uniprotkb:CHMP1B(gene name)|psi-mi:CHMP1B(display_short)|uniprotkb:C18orf2(gene name synonym)|uniprotkb:Chromatin-modifying protein 1b(gene name synonym)|uniprotkb:CHMP1.5(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 46-2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808040|imex:IM-13779-1214	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001645(Folylpolyglutamate synthetase)|interpro:IPR013221(Mur ligase, central)|refseq:YP_169418.1|go:""GO:0004326""(tetrahydrofolylpolyglutamate synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008841""(dihydrofolate synthase activity)|go:""GO:0046654""(tetrahydrofolate biosynthetic process)|go:""GO:0046656""(folic acid biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_003020032.1|interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR036565|interpro:IPR036615"	"refseq:NP_065145.2|panther:PTHR10476(orthology-group)|dip:DIP-48534N|ensembl:ENSG00000255112.3(gene)|ensembl:ENST00000526991.3(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0000776""(kinetochore)|go:""GO:0000815""(ESCRT III complex)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005771""(multivesicular body)|go:""GO:0005828""(kinetochore microtubule)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006914""(autophagy)|go:""GO:0006997""(nucleus organization)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0010008""(endosome membrane)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015031""(protein transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030117""(membrane coat)|go:""GO:0030496""(midbody)|go:""GO:0031468""(nuclear membrane reassembly)|go:""GO:0032509""(endosome transport via multivesicular body sorting pathway)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045324""(late endosome to vacuole transport)|go:""GO:0046761""(viral budding from plasma membrane)|go:""GO:0051301""(cell division)|go:""GO:0051469""(vesicle fusion with vacuole)|go:""GO:0061763""(multivesicular body-lysosome fusion)|go:""GO:0061952""(midbody abscission)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071985""(multivesicular body sorting pathway)|go:""GO:0090148""(membrane fission)|go:""GO:0090541""(MIT domain binding)|go:""GO:0097352""(autophagosome maturation)|go:""GO:1901673""(regulation of mitotic spindle assembly)|go:""GO:1902774""(late endosome to lysosome transport)|go:""GO:1904903""(ESCRT III complex disassembly)|go:""GO:1904930""(amphisome membrane)|interpro:IPR005024(Snf7)|mint:Q7LBR1|rcsb pdb:3EAB|rcsb pdb:3JC1|rcsb pdb:4TXQ|rcsb pdb:4TXR|rcsb pdb:6E8G|rcsb pdb:6TZ4|rcsb pdb:6TZ5|rcsb pdb:6TZ9"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/22	rogid:yCx5zGRSAd5ahIDsKUCa0YzZPVg177416	rogid:JBzgWtpzZ/td6JuSSCIx5xpZE7M9606	intact-crc:A356E2395C197FB1|rigid:oWcjxsXfwdBQeWaQfvblciiTwQU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEH1	uniprotkb:Q9HCK8	intact:EBI-2796391|uniprotkb:A0A0G2RMG3	intact:EBI-1169146|uniprotkb:Q68DQ0|uniprotkb:Q8N3Z9|uniprotkb:Q8NCY4|uniprotkb:Q8TBR9|uniprotkb:Q96F26|uniprotkb:Q4G0D8|uniprotkb:Q6DKH9|uniprotkb:Q6P440|uniprotkb:Q6ZNL7|ensembl:ENSP00000451601.1|ensembl:ENSP00000495070.1|ensembl:ENSP00000495240.1	psi-mi:q5neh1_fratt(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:FTT_1664(locus name)	psi-mi:chd8_human(display_long)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808047|imex:IM-13779-1213	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_170571.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|refseq:WP_003022611.1|interpro:IPR036897|interpro:IPR036914"	"panther:PTHR45623(orthology-group)|dip:DIP-38021N|ensembl:ENSG00000100888.15(gene)|ensembl:ENST00000557364.6(transcript)|ensembl:ENST00000643469.1(transcript)|ensembl:ENST00000646647.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0002039""(p53 binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006397""(mRNA processing)|go:""GO:0007420""(brain development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035176""(social behavior)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042393""(histone binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045945""(positive regulation of transcription by RNA polymerase III)|go:""GO:0048565""(digestive tract development)|go:""GO:0060134""(prepulse inhibition)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071339""(MLL1 complex)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140658""(ATP-dependent chromatin remodeler activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|go:""GO:2000270""(negative regulation of fibroblast apoptotic process)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR034724|interpro:IPR037259|interpro:IPR038718|interpro:IPR049730|interpro:IPR051493|mint:Q9HCK8|rcsb pdb:2CKA|rcsb pdb:2DL6|reactome:R-HSA-3769402|refseq:NP_001164100.1|refseq:NP_065971.2|efo:""Orphanet:261229""|efo:""Orphanet:642675"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:YUFWDuTGDB9kX/RHTWI6fMTHxU0177416	rogid:QwADLvHNwK00OAboBtAkqaICd489606	intact-crc:36CE0956935B1423|rigid:5MiGiEXofO4co/uxhyz3IifbZd0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFK4	uniprotkb:Q9NX63	intact:EBI-2800809	intact:EBI-743375|ensembl:ENSP00000262570.5	psi-mi:q5nfk4_fratt(display_long)|uniprotkb:serA(gene name)|psi-mi:serA(display_short)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:FTT_1230(locus name)	psi-mi:mic19_human(display_long)|uniprotkb:CHCHD3(gene name)|psi-mi:CHCHD3(display_short)|uniprotkb:MINOS3(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:MIC19(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808054|imex:IM-13779-1215	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|refseq:YP_170188.1|go:""GO:0004617""(phosphoglycerate dehydrogenase activity)|go:""GO:0051287""(NAD binding)|interpro:IPR054480|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR050418|interpro:IPR045865"	"refseq:NP_060282.1|refseq:NP_001304106.1|ensembl:ENSG00000106554.13(gene)|ensembl:ENST00000262570.10(transcript)|go:""GO:0001401""(SAM complex)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0007007""(inner mitochondrial membrane organization)|go:""GO:0008053""(mitochondrial fusion)|go:""GO:0019902""(phosphatase binding)|go:""GO:0042407""(cristae formation)|go:""GO:0044284""(mitochondrial crista junction)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061617""(MICOS complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140275""(MIB complex)|interpro:IPR007964(Protein of unknown function DUF737)|interpro:IPR052632|mint:Q9NX63|reactome:R-HSA-1268020|reactome:R-HSA-8949613|panther:PTHR21588(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:P4eaT+D8P7LiY4FAAPcBTski4tA177416	rogid:Ox0+PoTPYwxw8cKNqpzvSCg+Smg9606	intact-crc:C146361F938A6D9A|rigid:QNZMirfMbT3gOXb6qszL7q18zW4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI96	uniprotkb:Q9Y6H1	intact:EBI-2806028	intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812.3	psi-mi:ddl_fratt(display_long)|uniprotkb:D-Ala-D-Ala ligase(gene name synonym)|uniprotkb:D-alanylalanine synthetase(gene name synonym)|uniprotkb:FTT_0185(locus name)|uniprotkb:ddl(gene name)|psi-mi:ddl(display_short)	psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808061|imex:IM-13779-1216	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169246.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR000291(D-alanine--D-alanine ligase/VANA/B/C, conserved site)|interpro:IPR005905(D-alanine--D-alanine ligase)|interpro:IPR011095(D-alanine--D-alanine ligase, C-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008716""(D-alanine-D-alanine ligase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0071555""(cell wall organization)|refseq:WP_003027426.1"	"refseq:NP_057223.1|ensembl:ENSG00000106153.14(gene)|ensembl:ENST00000395422.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0043467""(regulation of generation of precursor metabolites and energy)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1900037""(regulation of cellular response to hypoxia)|go:""GO:1905448""(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|interpro:IPR055304|mint:Q9Y6H1|reactome:R-HSA-1268020|reactome:R-HSA-9837999|panther:PTHR13523(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ofh+mb/jW5UTankYJCJcXlF58wA177416	rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606	intact-crc:2948F812280370E8|rigid:pB56dG9dn+EZzLxSHIX9GuyWN2c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95766	uniprotkb:Q5NIF4	intact:EBI-2692658|uniprotkb:Q9Y359|uniprotkb:A2RU45|uniprotkb:Q9UG65	intact:EBI-2802846	psi-mi:cg028_human(display_long)|uniprotkb:C7orf28A(gene name)|psi-mi:C7orf28A(display_short)|uniprotkb:C7orf28B(gene name)|psi-mi:C7orf28B(display_short)	psi-mi:rf3_fratt(display_long)|uniprotkb:FTT_0118(locus name)|uniprotkb:prfC(gene name)|psi-mi:prfC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808075|imex:IM-13779-1217	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR032090|interpro:IPR004548(Peptide chain release factor 3)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:YP_169188.1|interpro:IPR027417|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006449""(regulation of translational termination)|go:""GO:0016149""(translation release factor activity, codon specific)|go:""GO:0016150""(translation release factor activity, codon nonspecific)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR031157|refseq:WP_003019866.1|interpro:IPR038467|interpro:IPR035647|interpro:IPR053905|interpro:IPR041732"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MKDR/bbj1dZLSUFFr7Ihd3vuw7o9606	rogid:exUjAaNXwgX443c8S/YiaeKgFoM177416	intact-crc:E6D1C7ACCEE88018|rigid:ibskp7G1LOBdV5pYpDFDbskMWFs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFW7	uniprotkb:Q68CZ6	intact:EBI-2800866	intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706.4|ensembl:ENSP00000392903.2|uniprotkb:B4DF64	psi-mi:sya_fratt(display_long)|uniprotkb:alaS(gene name)|psi-mi:alaS(display_short)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1096c(locus name)	psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808068|imex:IM-13779-1218	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_170075.1|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR018162|interpro:IPR018165|interpro:IPR018164|interpro:IPR023033|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004813""(alanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006419""(alanyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:WP_011242268.1|interpro:IPR050058|interpro:IPR045864"	"refseq:NP_078787.2|ensembl:ENSG00000214367.10(gene)|ensembl:ENST00000243706.8(transcript)|ensembl:ENST00000443786.3(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0007098""(centrosome cycle)|go:""GO:0010968""(regulation of microtubule nucleation)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0051225""(spindle assembly)|go:""GO:0051301""(cell division)|go:""GO:0070652""(HAUS complex)|go:""GO:0072686""(mitotic spindle)|go:""GO:1990498""(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:7SQK|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N|panther:PTHR19378(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/05	rogid:jCXq3A5fOs0cyqLU6IhdKsy5Apg177416	rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606	intact-crc:3CA2E4114ECA78D0|rigid:5GwzNSvljju5J3kPlkQBJPnjVYM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5SZL2	uniprotkb:Q5NEX3	intact:EBI-2514702|uniprotkb:Q2TAM2|uniprotkb:Q9H289|uniprotkb:A1A4E1|uniprotkb:A2IDE5|uniprotkb:Q5T323|uniprotkb:Q7Z5K7|ensembl:ENSP00000357477.3|uniprotkb:A2A3P2|uniprotkb:F8W6J2|uniprotkb:G3V0H3	intact:EBI-2797977|uniprotkb:A0A0G2RMN5	psi-mi:ce85l_human(display_long)|uniprotkb:CEP85L(gene name)|psi-mi:CEP85L(display_short)|uniprotkb:C6orf204(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-15(gene name synonym)	psi-mi:q5nex3_fratt(display_long)|uniprotkb:aceF(gene name)|psi-mi:aceF(display_short)|uniprotkb:FTT_1484c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808082|imex:IM-13779-1219	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111860.14(gene)|ensembl:ENST00000368491.8(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001764""(neuron migration)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|interpro:IPR040210|refseq:NP_001035940.1|refseq:NP_001171506.1|refseq:NP_996804.2|refseq:XP_011534111.1|refseq:XP_016866335.1|efo:""Orphanet:572013""|panther:PTHR31075(orthology-group)"	"go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006086""(pyruvate decarboxylation to acetyl-CoA)|go:""GO:0006096""(glycolytic process)|go:""GO:0031405""(lipoic acid binding)|go:""GO:0045254""(pyruvate dehydrogenase complex)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR006256(Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|refseq:YP_170419.1|refseq:WP_003022341.1|interpro:IPR023213|interpro:IPR036625|interpro:IPR050743"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:N15ebFbq7U88FFmEjre+dOJsgeA9606	rogid:YXI43uZwUchXxoDxiv+5yFM3SDk177416	intact-crc:887B5FC01600BA23|rigid:b5e08TCubGwM4ns8/pPiP8ZnxwA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHD1	uniprotkb:Q96MT8	intact:EBI-2799605|uniprotkb:A0A0G2RPC0	intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129.1|ensembl:ENSP00000475903.1|ensembl:ENSP00000502085.1|ensembl:ENSP00000506896.1	psi-mi:q5nhd1_fratt(display_long)|uniprotkb:grxC(gene name)|psi-mi:grxC(display_short)|uniprotkb:FTT_0532c(locus name)	psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808104|imex:IM-13779-1223	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR002109(Glutaredoxin)|interpro:IPR014025(Glutaredoxin subgroup)|interpro:IPR000358(Ribonucleotide reductase)|refseq:YP_169561.1|go:""GO:0004748""(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:""GO:0009263""(deoxyribonucleotide biosynthetic process)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_003023235.1|interpro:IPR036249|interpro:IPR011900(Glutaredoxin, GrxC)|interpro:IPR033909|interpro:IPR012348(Ribonucleotide reductase-related)"	"efo:""Orphanet:2512""|dip:DIP-36374N|ensembl:ENSG00000182923.20(gene)|ensembl:ENST00000513612.7(transcript)|ensembl:ENST00000606977.5(transcript)|ensembl:ENST00000675561.1(transcript)|ensembl:ENST00000683596.1(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000922""(spindle pole)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0007099""(centriole replication)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050821""(protein stabilization)|go:""GO:0051225""(spindle assembly)|go:""GO:0051301""(cell division)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0098535""(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:""GO:1900045""(negative regulation of protein K63-linked ubiquitination)|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|rcsb pdb:7W91|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_011511496.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|panther:PTHR18875(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Zlpot7hmLVzAffGINLtgVgDpcoA177416	rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606	intact-crc:4A97971D7F479AF8|rigid:C8i1stIl71jXvfY6sett3zn0Lq0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGL8	uniprotkb:Q8IYT3	intact:EBI-2796116	intact:EBI-2808089|uniprotkb:Q9H5M3|uniprotkb:Q5VXB7|uniprotkb:Q96KA9|uniprotkb:Q6P9E4|ensembl:ENSP00000239374.6	psi-mi:syt_fratt(display_long)|uniprotkb:thrS(gene name)|psi-mi:thrS(display_short)|uniprotkb:Threonyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0817(locus name)	psi-mi:cc170_human(display_long)|uniprotkb:CCDC170(gene name)|psi-mi:CCDC170(display_short)|uniprotkb:C6orf97(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808097|imex:IM-13779-1220	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169824.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|interpro:IPR002320(Threonyl-tRNA synthetase, class IIa)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|refseq:WP_003020750.1|interpro:IPR033728|interpro:IPR036621|interpro:IPR045864|interpro:IPR047246|go:""GO:0000049""(tRNA binding)|go:""GO:0004829""(threonine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006435""(threonyl-tRNA aminoacylation)|go:""GO:0046872""(metal ion binding)"	"refseq:NP_079335.2|ensembl:ENSG00000120262.10(gene)|ensembl:ENST00000239374.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0008017""(microtubule binding)|go:""GO:0030054""(cell junction)|go:""GO:0036064""(ciliary basal body)|interpro:IPR039139|panther:PTHR18863(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mYG/RO6WmHDnsUAHonnk2kMKPh0177416	rogid:MPjgGyEjt9JujfywCRtTdE919EQ9606	intact-crc:9C597FB21FC6EEC0|rigid:n7VuFBsJPL77b3KyJQM06VUH/T4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43303	uniprotkb:Q5NFW7	intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803.5	intact:EBI-2800866	psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym)	psi-mi:sya_fratt(display_long)|uniprotkb:alaS(gene name)|psi-mi:alaS(display_short)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1096c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808125|imex:IM-13779-1222	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001310498.1|panther:PTHR13594(orthology-group)|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540.17(gene)|ensembl:ENST00000381396.9(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0007099""(centriole replication)|go:""GO:0032053""(ciliary basal body organization)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045724""(positive regulation of cilium assembly)|go:""GO:0051298""(centrosome duplication)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424"	"refseq:YP_170075.1|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR018162|interpro:IPR018165|interpro:IPR018164|interpro:IPR023033|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004813""(alanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006419""(alanyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:WP_011242268.1|interpro:IPR050058|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Gvda4RoDRcY+G50iRW5T+haubps9606	rogid:jCXq3A5fOs0cyqLU6IhdKsy5Apg177416	intact-crc:5C56432D487420D7|rigid:xiGsq3GASXfShSzq1l4VuWOxPyY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF74	uniprotkb:Q86XR8	intact:EBI-2796785|uniprotkb:A0A0G2RND4	intact:EBI-308614|uniprotkb:Q14704|uniprotkb:Q8IXP0|uniprotkb:Q9BVF9|uniprotkb:Q5JB46|uniprotkb:A0PJH1|uniprotkb:A8K5D0|uniprotkb:B4DDP5|ensembl:ENSP00000317902.5|uniprotkb:F5H5F7	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	psi-mi:cep57_human(display_long)|uniprotkb:CEP57(gene name)|psi-mi:CEP57(display_short)|uniprotkb:Testis-specific protein 57(gene name synonym)|uniprotkb:Translokin(gene name synonym)|uniprotkb:FGF2-interacting protein(gene name synonym)|uniprotkb:KIAA0092(gene name synonym)|uniprotkb:TSP57(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808111|imex:IM-13779-1221	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"ensembl:ENSG00000166037.11(gene)|ensembl:ENST00000325542.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0007286""(spermatid development)|go:""GO:0008017""(microtubule binding)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0017134""(fibroblast growth factor binding)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0051260""(protein homooligomerization)|interpro:IPR024957|interpro:IPR025913|interpro:IPR051756|mint:Q86XR8|rcsb pdb:4L0R|rcsb pdb:8IBH|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001230705.1|refseq:NP_001230706.1|refseq:NP_055494.2|refseq:XP_016874081.1|efo:""Orphanet:1052""|panther:PTHR19336(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	rogid:zlDjuw8lnfiXHeOeieJPekAcxD09606	intact-crc:CF5179B11055DB88|rigid:bKAWC7qwGEJAaYpl/2C8WxZKqsE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95319	uniprotkb:Q5NGC9	intact:EBI-949790|intact:EBI-1760395|uniprotkb:Q7KYU4|uniprotkb:Q8N499|uniprotkb:Q92950|uniprotkb:Q96NW9|uniprotkb:Q96RQ5|uniprotkb:Q96RQ6|uniprotkb:Q9UL67|intact:EBI-1965465|uniprotkb:B7ZAN9|ensembl:ENSP00000406451.2|ensembl:ENSP00000488582.1	intact:EBI-2798846|uniprotkb:A0A0G2RN34	psi-mi:celf2_human(display_long)|uniprotkb:CELF2(gene name)|psi-mi:CELF2(display_short)|uniprotkb:BRUNOL3(gene name synonym)|uniprotkb:CUGBP2(gene name synonym)|uniprotkb:ETR3(gene name synonym)|uniprotkb:NAPOR(gene name synonym)|uniprotkb:CUG-BP- and ETR-3-like factor 2(gene name synonym)|uniprotkb:Bruno-like protein 3(gene name synonym)|uniprotkb:RNA-binding protein BRUNOL-3(gene name synonym)|uniprotkb:CUG triplet repeat RNA-binding protein 2(gene name synonym)|uniprotkb:ELAV-type RNA-binding protein 3(gene name synonym)|uniprotkb:Neuroblastoma apoptosis-related RNA-binding protein(gene name synonym)	psi-mi:q5ngc9_fratt(display_long)|uniprotkb:ribF(gene name)|psi-mi:ribF(display_short)|uniprotkb:FTT_0916c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808118|imex:IM-13779-1224	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:442835""|ensembl:ENSG00000048740.19(gene)|ensembl:ENST00000416382.6(transcript)|ensembl:ENST00000631460.1(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006376""(mRNA splice site recognition)|go:""GO:0006396""(RNA processing)|go:""GO:0008016""(regulation of heart contraction)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0090543""(Flemming body)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034196|interpro:IPR034198|interpro:IPR034199|interpro:IPR035979|mint:O95319|rcsb pdb:2MY7|rcsb pdb:2MY8|rcsb pdb:4LJM|rcsb pdb:4LMZ|rcsb pdb:4TLQ|rcsb pdb:5M8I|refseq:NP_001020247.1|refseq:NP_001020248.1|refseq:NP_001077060.1|refseq:NP_001313246.1|refseq:NP_001313247.1|refseq:NP_001313248.1|refseq:NP_001313249.1|refseq:NP_001313250.1|refseq:NP_001313253.1|refseq:NP_001313257.1|refseq:NP_001313258.1|refseq:NP_001313259.1|refseq:NP_001313261.1|refseq:NP_001313262.1|refseq:NP_001313263.1|refseq:NP_001313265.1|refseq:NP_001313268.1|refseq:NP_001313269.1|refseq:NP_001313271.1|refseq:NP_001313272.1|refseq:NP_001313273.1|refseq:NP_001313274.1|refseq:NP_001313277.1|refseq:NP_001313278.1|refseq:NP_006552.3|refseq:XP_011517596.1|refseq:XP_011517599.1|refseq:XP_016871042.1|refseq:XP_016871043.1|panther:PTHR24012(orthology-group)"	"interpro:IPR015864(FAD synthetase)|interpro:IPR023468|interpro:IPR002606(Riboflavin kinase/FAD synthetase)|interpro:IPR015865(Riboflavin kinase)|interpro:IPR023465|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:YP_169913.1|go:""GO:0003919""(FMN adenylyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006747""(FAD biosynthetic process)|go:""GO:0008531""(riboflavin kinase activity)|go:""GO:0009231""(riboflavin biosynthetic process)|go:""GO:0009398""(FMN biosynthetic process)|refseq:WP_003020933.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h4C0NcgtNScSaExjkrwSQIUXAaQ9606	rogid:bJtuE0PZfAxedp1n4UrRXeOTMcg177416	intact-crc:58798A6BFA6D6479|rigid:khSskoJofByBXeCv8eCeF3IWyFs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV7	uniprotkb:P60953	intact:EBI-2796192	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:katg_fratt(display_long)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:FTT_0721c(locus name)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808150|imex:IM-13779-1227	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169735.1|interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|refseq:WP_003020536.1|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/07	rogid:UVLspYdPWJwb7VPBG0xNq1Pp2KQ177416	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:8735D57BAF62887E|rigid:24Wtyzxt7+wk2rDrB0Jup2W1TsQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75956	uniprotkb:Q5NET3	intact:EBI-2808135|ensembl:ENSP00000301488.4	intact:EBI-2801773	psi-mi:cdka2_human(display_long)|uniprotkb:CDK2AP2(gene name)|psi-mi:CDK2AP2(display_short)|uniprotkb:DOC1R(gene name synonym)|uniprotkb:DOC-1-related protein(gene name synonym)	psi-mi:q5net3_fratt(display_long)|uniprotkb:fadE(gene name)|psi-mi:fadE(display_short)|uniprotkb:FTT_1529(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808132|imex:IM-13779-1226	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005842.1|ensembl:ENSG00000167797.8(gene)|ensembl:ENST00000301488.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005874""(microtubule)|go:""GO:0016581""(NuRD complex)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:2000035""(regulation of stem cell division)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR017266(Cyclin-dependent kinase 2-associated protein 2)|mint:O75956|rcsb pdb:2M1L|panther:PTHR22607(orthology-group)"	"interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR015396(Protein of unknown function DUF1974)|refseq:YP_170459.3|go:""GO:0004466""(long-chain fatty acyl-CoA dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0033539""(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070991""(medium-chain fatty acyl-CoA dehydrogenase activity)|interpro:IPR036250|interpro:IPR037069|interpro:IPR050741|interpro:IPR046373"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9cZX74ns66FiDOoI8Y5lLD/BHyY9606	rogid:kKeqoKaBPWvIJmVTDMU1BWCVmTc177416	intact-crc:D79DBB54CD34BAEE|rigid:M+O0XNa/GyimAn7donOYGkxwIvE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99459	uniprotkb:Q5NIB3	intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532.3	intact:EBI-2805819|uniprotkb:A0A0G2RPX7	psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym)	psi-mi:q5nib3_fratt(display_long)|uniprotkb:parE(gene name)|psi-mi:parE(display_short)|uniprotkb:Topoisomerase IV subunit B(gene name synonym)|uniprotkb:FTT_0163c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808143|imex:IM-13779-1225	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR45885(orthology-group)|refseq:NP_001244.1|ensembl:ENSG00000096401.8(gene)|ensembl:ENST00000371477.4(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000974""(Prp19 complex)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0042802""(identical protein binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071987""(WD40-repeat domain binding)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|interpro:IPR047240|interpro:IPR047242|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8RO2|rcsb pdb:9FMD|reactome:R-HSA-72163|dip:DIP-31731N"	"refseq:YP_169229.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR005737(DNA topoisomerase IV, subunit B, Gram-negative)|interpro:IPR006171(TOPRIM)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0006265""(DNA topological change)|go:""GO:0007059""(chromosome segregation)|go:""GO:0034335""(DNA negative supercoiling activity)|refseq:WP_003019941.1|interpro:IPR036890"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/21	rogid:ZNRraJHn//46wKLSx7xtZju/lr09606	rogid:eSUwaDHwHNDsicxk7YgYrDfmnIE177416	intact-crc:01D8488DE34124ED|rigid:TSDtDP1aBVVDiocC7Lwxu3RrdLw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI33	uniprotkb:P30260	intact:EBI-2800112|uniprotkb:A0A0G2RMA5	intact:EBI-994813|uniprotkb:Q16349|uniprotkb:Q96F35|uniprotkb:G3V1C4|intact:EBI-10972530|ensembl:ENSP00000066544.3	psi-mi:q5ni33_fratt(display_long)|uniprotkb:FTT_0257(locus name)	psi-mi:cdc27_human(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:H-NUC(gene name synonym)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808164|imex:IM-13779-1231	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169309.1|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0006402""(mRNA catabolic process)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:WP_003021737.1|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR036388|interpro:IPR050180"	"refseq:NP_001107563.1|refseq:NP_001247.3|dip:DIP-36422N|ensembl:ENSG00000004897.12(gene)|ensembl:ENST00000066544.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005680""(anaphase-promoting complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0007091""(metaphase/anaphase transition of mitotic cell cycle)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031145""(anaphase-promoting complex-dependent catabolic process)|go:""GO:0051301""(cell division)|go:""GO:0051445""(regulation of meiotic cell cycle)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0072686""(mitotic spindle)|go:""GO:0141198""(protein branched polyubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P30260|rcsb pdb:3T1N|rcsb pdb:4RG6|rcsb pdb:4RG7|rcsb pdb:4RG9|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|rcsb pdb:8PKP|rcsb pdb:8TAR|rcsb pdb:8TAU|rcsb pdb:9FGQ|rcsb pdb:9GAW|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSP00000066544.3|ensembl:ENST00000531206.5|ensembl:ENSP00000434614.1|panther:PTHR12558(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:T86jKHSo3mAW/ak8vzq3vAvG0j0177416	rogid:YOrJCRal5ZfO7kP2b8FPon0Yytw9606	intact-crc:F0B31F7C491C9805|rigid:Vshjp1K30kxJZBqRnkEwY8irLnM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13042	uniprotkb:Q5NG10	intact:EBI-994830|uniprotkb:Q96AE6|uniprotkb:Q9Y564|uniprotkb:A2A365|uniprotkb:Q5T8C8|uniprotkb:Q7Z651|ensembl:ENSP00000348554.3|ensembl:ENSP00000353549.3	intact:EBI-2808174	psi-mi:cdc16_human(display_long)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short)	psi-mi:cysn_fratt(display_long)|uniprotkb:cysN(gene name)|psi-mi:cysN(display_short)|uniprotkb:ATP-sulfurylase large subunit(gene name synonym)|uniprotkb:Sulfate adenylate transferase(gene name synonym)|uniprotkb:FTT_1050c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808171|imex:IM-13779-1230	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001072113.1|refseq:NP_003894.3|refseq:NP_001305446.1|refseq:NP_001305447.1|refseq:NP_001317030.1|refseq:NP_001317033.1|refseq:NP_001317034.1|refseq:XP_016876322.1|dip:DIP-36423N|ensembl:ENSG00000130177.16(gene)|ensembl:ENST00000356221.8(transcript)|ensembl:ENST00000360383.7(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005680""(anaphase-promoting complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031145""(anaphase-promoting complex-dependent catabolic process)|go:""GO:0045842""(positive regulation of mitotic metaphase/anaphase transition)|go:""GO:0051301""(cell division)|go:""GO:0051445""(regulation of meiotic cell cycle)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0072686""(mitotic spindle)|go:""GO:0141198""(protein branched polyubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q13042|rcsb pdb:3HYM|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|rcsb pdb:8PKP|rcsb pdb:8TAR|rcsb pdb:8TAU|rcsb pdb:9GAW|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|panther:PTHR12558(orthology-group)"	"interpro:IPR050100|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011779(Sulphate adenylyltransferase, large subunit)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:YP_170032.1|interpro:IPR027417|go:""GO:0000103""(sulfate assimilation)|go:""GO:0003924""(GTPase activity)|go:""GO:0004781""(""sulfate adenylyltransferase (ATP) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0070814""(hydrogen sulfide biosynthetic process)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR054696|interpro:IPR031157|interpro:IPR041757|interpro:IPR044138|interpro:IPR044139|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|refseq:WP_003021169.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606	rogid:YuWif6cKCJFOuD9Ai1sqa9dQiOs177416	intact-crc:B1A566F9067771FC|rigid:spxFot+4tF8/USDYAwcajBSKesI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:Q13042	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-994830|uniprotkb:Q96AE6|uniprotkb:Q9Y564|uniprotkb:A2A365|uniprotkb:Q5T8C8|uniprotkb:Q7Z651|ensembl:ENSP00000348554.3|ensembl:ENSP00000353549.3	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:cdc16_human(display_long)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808182|imex:IM-13779-1228	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"refseq:NP_001072113.1|refseq:NP_003894.3|refseq:NP_001305446.1|refseq:NP_001305447.1|refseq:NP_001317030.1|refseq:NP_001317033.1|refseq:NP_001317034.1|refseq:XP_016876322.1|dip:DIP-36423N|ensembl:ENSG00000130177.16(gene)|ensembl:ENST00000356221.8(transcript)|ensembl:ENST00000360383.7(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005680""(anaphase-promoting complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031145""(anaphase-promoting complex-dependent catabolic process)|go:""GO:0045842""(positive regulation of mitotic metaphase/anaphase transition)|go:""GO:0051301""(cell division)|go:""GO:0051445""(regulation of meiotic cell cycle)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0072686""(mitotic spindle)|go:""GO:0141198""(protein branched polyubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q13042|rcsb pdb:3HYM|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|rcsb pdb:8PKP|rcsb pdb:8TAR|rcsb pdb:8TAU|rcsb pdb:9GAW|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|panther:PTHR12558(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606	intact-crc:01AD84F906653892|rigid:0AvPSp3a1C/SaJ3JPkpA7s+qcFQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P60953	uniprotkb:Q5NEA3	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	intact:EBI-2800073|uniprotkb:A0A0G2RPN2	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:q5nea3_fratt(display_long)|uniprotkb:ipdC(gene name)|psi-mi:ipdC(display_short)|uniprotkb:FTT_1744c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808157|imex:IM-13779-1229	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	"interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|refseq:YP_170639.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000949""(aromatic amino acid family catabolic process to alcohol via Ehrlich pathway)|go:""GO:0004737""(pyruvate decarboxylase activity)|go:""GO:0005829""(cytosol)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0047434""(indolepyruvate decarboxylase activity)|interpro:IPR029035|interpro:IPR029061|refseq:WP_011242294.1|interpro:IPR047213|interpro:IPR047214"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/07	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rogid:Iid6pPFvRJ+Zqx6I5jItCfC+Qb4177416	intact-crc:37C8377BAE152C29|rigid:UnsSeDR40lFcfBKOdeFhFLh5uqM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIF9	uniprotkb:Q6QIN9	intact:EBI-2799085|uniprotkb:A0A0G2RQ41	intact:EBI-2808199	psi-mi:q5nif9_fratt(display_long)|uniprotkb:Phosphodeoxyribomutase(gene name synonym)|uniprotkb:deoB(gene name)|psi-mi:deoB(display_short)|uniprotkb:FTT_0113(locus name)	psi-mi:q6qin9_human(display_long)|uniprotkb:PTPRC(gene name)|psi-mi:PTPRC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808196|imex:IM-13779-1232	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR010045(Phosphopentomutase)|interpro:IPR006124(Metalloenzyme)|interpro:IPR024052|refseq:YP_169183.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006015""(5-phosphoribose 1-diphosphate biosynthetic process)|go:""GO:0006018""(2-deoxyribose 1-phosphate catabolic process)|go:""GO:0008973""(phosphopentomutase activity)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0043094""(metabolic compound salvage)|refseq:WP_003019856.1"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:A5Ci9aiQ72qwd1VqfoGwme/pcM4177416	rogid:EKmjXc6F9hgfqYw8KlpDEpc9OQk9606	intact-crc:F440E6D3BFBE9F05|rigid:LYqeXUgSsLF9wyxR7Sx1fMYY9hk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6QIN9	uniprotkb:Q5NEE1	intact:EBI-2808199	intact:EBI-2796953	psi-mi:q6qin9_human(display_long)|uniprotkb:PTPRC(gene name)|psi-mi:PTPRC(display_short)	psi-mi:ch60_fratt(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:FTT_1696(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808207|imex:IM-13779-1235	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016853""(isomerase activity)|go:""GO:0042026""(protein refolding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|refseq:YP_170601.1|interpro:IPR027410|interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|refseq:WP_003022663.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EKmjXc6F9hgfqYw8KlpDEpc9OQk9606	rogid:4AyWqh/uQMYXxihW2YyAvevPM4k177416	intact-crc:645DC308CDE4DC16|rigid:SUDv0UskkGQoDe3xkXThyzWigJk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NII1	uniprotkb:O43866	intact:EBI-2797156|uniprotkb:A0A0G2RN00	intact:EBI-2623436|uniprotkb:A8K7M5|uniprotkb:Q6UX63|ensembl:ENSP00000357156.4	psi-mi:q5nii1_fratt(display_long)|uniprotkb:acnA(gene name)|psi-mi:acnA(display_short)|uniprotkb:FTT_0087(locus name)	psi-mi:cd5l_human(display_long)|uniprotkb:API6(gene name synonym)|uniprotkb:CT-2(gene name synonym)|uniprotkb:IgM-associated peptide(gene name synonym)|uniprotkb:SP-alpha(gene name synonym)|uniprotkb:UNQ203/PRO229(orf name)|uniprotkb:Apoptosis inhibitor expressed by macrophages(gene name synonym)|uniprotkb:CD5L(gene name)|psi-mi:CD5L(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808189|imex:IM-13779-1234	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR044137|refseq:YP_169161.1|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR018136|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|refseq:WP_003019815.1|interpro:IPR036008"	"refseq:NP_005885.1|ensembl:ENSG00000073754.6(gene)|ensembl:ENST00000368174.5(transcript)|go:""GO:0002376""(immune system process)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0009986""(cell surface)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0031638""(zymogen activation)|go:""GO:0072562""(blood microparticle)|go:""GO:1903661""(positive regulation of complement-dependent cytotoxicity)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR036772|rcsb pdb:8WYR|rcsb pdb:8WYS|refseq:NP_001334627.1|panther:PTHR48071(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FGVUBUKOHsDquKU0LqPkXCpRg+o177416	rogid:g+Yen5g8QKKkkcmIVSd0eylQJYg9606	intact-crc:F61C3869ECFE05B8|rigid:1SCjjXjkZ+a8xz9uj3rDAwgY84E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16671	uniprotkb:Q5NG28	intact:EBI-2808214|uniprotkb:Q9BQC2|uniprotkb:Q9BPZ8|uniprotkb:Q9BZN5|uniprotkb:Q9BZM8|uniprotkb:Q8TCV7|uniprotkb:Q9BZN3|uniprotkb:Q16093|uniprotkb:Q13966|uniprotkb:Q9BZN4|ensembl:ENSP00000308165.7|ensembl:ENSP00000378268.3|ensembl:ENSP00000399421.1|ensembl:ENSP00000411411.1|ensembl:ENSP00000415743.2|uniprotkb:D9IX66|uniprotkb:D9IX67|uniprotkb:D9IX68|uniprotkb:D9IX69	intact:EBI-2802768|uniprotkb:A0A0G2RPI9	psi-mi:cd36_human(display_long)|uniprotkb:GP3B(gene name synonym)|uniprotkb:GP4(gene name synonym)|uniprotkb:Platelet glycoprotein IV(gene name synonym)|uniprotkb:Glycoprotein IIIb(gene name synonym)|uniprotkb:Leukocyte differentiation antigen CD36(gene name synonym)|uniprotkb:PAS IV(gene name synonym)|uniprotkb:PAS-4(gene name synonym)|uniprotkb:Platelet collagen receptor(gene name synonym)|uniprotkb:Fatty acid translocase(gene name synonym)|uniprotkb:Thrombospondin receptor(gene name synonym)|uniprotkb:CD36(gene name)|psi-mi:CD36(display_short)	psi-mi:q5ng28_fratt(display_long)|uniprotkb:dacD(gene name)|psi-mi:dacD(display_short)|uniprotkb:FTT_1029(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808227|imex:IM-13779-1233	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000063.2|refseq:NP_001001547.1|refseq:NP_001001548.1|refseq:NP_001120915.1|refseq:NP_001120916.1|refseq:XP_005250770.1|refseq:XP_005250771.1|refseq:XP_005250772.1|ensembl:ENSG00000135218.19(gene)|ensembl:ENST00000309881.11(transcript)|ensembl:ENST00000394788.7(transcript)|ensembl:ENST00000432207.5(transcript)|ensembl:ENST00000435819.5(transcript)|ensembl:ENST00000447544.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0002532""(production of molecular mediator involved in inflammatory response)|go:""GO:0005041""(low-density lipoprotein particle receptor activity)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006910""(phagocytosis, recognition)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007155""(cell adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007596""(blood coagulation)|go:""GO:0008035""(high-density lipoprotein particle binding)|go:""GO:0008289""(lipid binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010886""(positive regulation of cholesterol storage)|go:""GO:0015636""(short-chain fatty acid transmembrane transporter activity)|go:""GO:0015908""(fatty acid transport)|go:""GO:0015909""(long-chain fatty acid transport)|go:""GO:0015911""(long-chain fatty acid import across plasma membrane)|go:""GO:0015912""(short-chain fatty acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019915""(lipid storage)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0030169""(low-density lipoprotein particle binding)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030299""(intestinal cholesterol absorption)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031092""(platelet alpha granule membrane)|go:""GO:0031526""(brush border membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0031664""(regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033993""(response to lipid)|go:""GO:0034121""(regulation of toll-like receptor signaling pathway)|go:""GO:0034197""(triglyceride transport)|go:""GO:0034381""(plasma lipoprotein particle clearance)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0035325""(Toll-like receptor binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035634""(response to stilbenoid)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0038060""(nitric oxide-cGMP-mediated signaling)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0044539""(long-chain fatty acid import into cell)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0050892""(intestinal absorption)|go:""GO:0050909""(sensory perception of taste)|go:""GO:0055096""(low-density lipoprotein particle mediated signaling)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070508""(cholesterol import)|go:""GO:0070542""(response to fatty acid)|go:""GO:0070543""(response to linoleic acid)|go:""GO:0070892""(lipoteichoic acid immune receptor activity)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071447""(cellular response to hydroperoxide)|go:""GO:0071726""(cellular response to diacyl bacterial lipopeptide)|go:""GO:0071813""(lipoprotein particle binding)|go:""GO:0071944""(cell periphery)|go:""GO:0097009""(energy homeostasis)|go:""GO:0098900""(regulation of action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140052""(cellular response to oxidised low-density lipoprotein particle stimulus)|go:""GO:0150024""(oxidised low-density lipoprotein particle clearance)|go:""GO:0150025""(oxidised low-density lipoprotein particle receptor activity)|go:""GO:0150094""(amyloid-beta clearance by cellular catabolic process)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1901480""(oleate transmembrane transporter activity)|go:""GO:1903428""(positive regulation of reactive oxygen species biosynthetic process)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990379""(lipid transport across blood-brain barrier)|go:""GO:2000121""(regulation of removal of superoxide radicals)|go:""GO:2000334""(positive regulation of blood microparticle formation)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|rcsb pdb:5LGD|reactome:R-HSA-114608|reactome:R-HSA-1236973|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-168188|reactome:R-HSA-1989781|reactome:R-HSA-3000471|reactome:R-HSA-381340|reactome:R-HSA-434313|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-9841922|refseq:NP_001276837.1|refseq:NP_001276838.1|refseq:NP_001276840.1|panther:PTHR11923(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015956(Penicillin-binding protein-associated)|interpro:IPR018044|interpro:IPR012907(Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal)|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:YP_170014.1|refseq:WP_003021136.1|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|rcsb pdb:6OSU|mint:Q5NG28|interpro:IPR037167"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aYX4Uyq9gXqLN3pgTWyKWGQmL5w9606	rogid:EYTPcD8JUkej9Gvps0ogQD5aQ1c177416	intact-crc:30C1CD7007373FF6|rigid:EJm1qwn5dY2UaoWdV7TjNU0pL5A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11836	uniprotkb:Q5NG93	intact:EBI-2808234|uniprotkb:A6NMS4|uniprotkb:P08984|uniprotkb:Q13963|uniprotkb:B4DT24|ensembl:ENSP00000314620.7|ensembl:ENSP00000374589.2|ensembl:ENSP00000433277.1|ensembl:ENSP00000501369.1	intact:EBI-2797241|uniprotkb:A0A0G2RNP8	psi-mi:cd20_human(display_long)|uniprotkb:MS4A1(gene name)|psi-mi:MS4A1(display_short)|uniprotkb:CD20(gene name synonym)|uniprotkb:B-lymphocyte surface antigen B1(gene name synonym)|uniprotkb:Bp35(gene name synonym)|uniprotkb:Leukocyte surface antigen Leu-16(gene name synonym)|uniprotkb:Membrane-spanning 4-domains subfamily A member 1(gene name synonym)	psi-mi:q5ng93_fratt(display_long)|uniprotkb:xthA(gene name)|psi-mi:xthA(display_short)|uniprotkb:FTT_0959c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808241|imex:IM-13779-1236	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000156738.18(gene)|ensembl:ENST00000345732.9(transcript)|ensembl:ENST00000389939.2(transcript)|ensembl:ENST00000534668.6(transcript)|ensembl:ENST00000674194.1(transcript)|go:""GO:0002115""(store-operated calcium entry)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006959""(humoral immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009617""(response to bacterium)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0042100""(B cell proliferation)|go:""GO:0042113""(B cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051262""(protein tetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902656""(calcium ion import into cytosol)|go:""GO:1905665""(positive regulation of calcium ion import across plasma membrane)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|mint:P11836|rcsb pdb:2OSL|rcsb pdb:3BKY|rcsb pdb:3PP4|rcsb pdb:6VJA|rcsb pdb:6Y90|rcsb pdb:6Y92|rcsb pdb:6Y97|rcsb pdb:6Y9A|refseq:NP_068769.2|refseq:NP_690605.1|efo:""Orphanet:1572""|panther:PTHR23320(orthology-group)"	"go:""GO:0003906""(""DNA-(apurinic or apyrimidinic site) endonuclease activity"")|go:""GO:0006284""(base-excision repair)|go:""GO:0008081""(phosphoric diester hydrolase activity)|go:""GO:0008311""(double-stranded DNA 3'-5' DNA exonuclease activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR004808(Exodeoxyribonuclease III xth)|refseq:YP_169949.1|refseq:WP_003021031.1|interpro:IPR036691"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AnlKRZ3H77etWyyZIldbXkJDRkk9606	rogid:UmV6e4+lqB1TTnnIHyqtaomo34c177416	intact-crc:C9FD530D82A558C2|rigid:IakSLjvTc9Xv9z+2VgdRmw9Hi2c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q2TAC2	uniprotkb:Q5NEX3	intact:EBI-2808286|uniprotkb:Q8IWG2|uniprotkb:A8MQC7|uniprotkb:Q8TER3|uniprotkb:A6NP51|ensembl:ENSP00000374292.5	intact:EBI-2797977|uniprotkb:A0A0G2RMN5	psi-mi:ccd57_human(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short)	psi-mi:q5nex3_fratt(display_long)|uniprotkb:aceF(gene name)|psi-mi:aceF(display_short)|uniprotkb:FTT_1484c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808283|imex:IM-13779-1240	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000176155.21(gene)|ensembl:ENST00000389641.9(transcript)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005876""(spindle microtubule)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007099""(centriole replication)|go:""GO:0034451""(centriolar satellite)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0060271""(cilium assembly)|interpro:IPR042481|refseq:NP_001303250.1|refseq:NP_932348.2|panther:PTHR46725(orthology-group)"	"go:""GO:0004742""(dihydrolipoyllysine-residue acetyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006086""(pyruvate decarboxylation to acetyl-CoA)|go:""GO:0006096""(glycolytic process)|go:""GO:0031405""(lipoic acid binding)|go:""GO:0045254""(pyruvate dehydrogenase complex)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR006256(Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|refseq:YP_170419.1|refseq:WP_003022341.1|interpro:IPR023213|interpro:IPR036625|interpro:IPR050743"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YDj66sk5KcrdUoP6zw9gIxHkomg9606	rogid:YXI43uZwUchXxoDxiv+5yFM3SDk177416	intact-crc:5BE5846EAB4F24DB|rigid:3o3RblG32KBuoNf27xur0iJeR4w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID2	uniprotkb:P32246	intact:EBI-2796292	intact:EBI-608322|uniprotkb:Q86VA9|ensembl:ENSP00000296140.3	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	psi-mi:ccr1_human(display_long)|uniprotkb:Macrophage inflammatory protein 1-alpha receptor(gene name synonym)|uniprotkb:RANTES-R(gene name synonym)|uniprotkb:HM145(gene name synonym)|uniprotkb:LD78 receptor(gene name synonym)|uniprotkb:CCR1(gene name)|psi-mi:CCR1(display_short)|uniprotkb:CMKBR1(gene name synonym)|uniprotkb:CMKR1(gene name synonym)|uniprotkb:SCYAR1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808276|imex:IM-13779-1238	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"ensembl:ENSG00000163823.4(gene)|ensembl:ENST00000296140.4(transcript)|go:""GO:0002407""(dendritic cell chemotaxis)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0004435""(phosphatidylinositol-4,5-bisphosphate phospholipase C activity)|go:""GO:0004950""(chemokine receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006887""(exocytosis)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007187""(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0009611""(response to wounding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016493""(C-C chemokine receptor activity)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019957""(C-C chemokine binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030502""(negative regulation of bone mineralization)|go:""GO:0035717""(""chemokine (C-C motif) ligand 7 binding"")|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071791""(""chemokine (C-C motif) ligand 5 binding"")|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002236(C-C chemokine receptor, type 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR050119|mint:P32246|rcsb pdb:7VL8|rcsb pdb:7VL9|rcsb pdb:7VLA|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|refseq:NP_001286.1|dip:DIP-5832N|efo:""Orphanet:117""|panther:PTHR10489(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	rogid:m8grSofEywwJfUzrRCNNjYrq6ps9606	intact-crc:A18E784BDB66ACFA|rigid:EsqHhJq/QGHaDRDpGYd+FIfioWc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFT9	uniprotkb:O75794	intact:EBI-2802405|uniprotkb:A0A0G2RN44	intact:EBI-2808248|uniprotkb:Q14107|uniprotkb:Q5T0L9|uniprotkb:Q5T0L4|uniprotkb:Q5T0L7|uniprotkb:Q5T0L8|uniprotkb:A8JZZ7|uniprotkb:Q5T0L5|ensembl:ENSP00000281141.4	psi-mi:q5nft9_fratt(display_long)|uniprotkb:cphA(gene name)|psi-mi:cphA(display_short)|uniprotkb:Cyanophycin synthase(gene name synonym)|uniprotkb:FTT_1130c(locus name)	psi-mi:cd123_human(display_long)|uniprotkb:Cell division cycle protein 123 homolog(gene name synonym)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:C10orf7(gene name synonym)|uniprotkb:D123(gene name synonym)|uniprotkb:HT-1080(gene name synonym)|uniprotkb:PZ32(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808259|imex:IM-13779-1237	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR011810(Cyanophycin synthetase)|interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|refseq:YP_170103.1|refseq:WP_003021315.1|go:""GO:0005524""(ATP binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0071160""(""cyanophycin synthetase activity (L-aspartate-adding)"")|go:""GO:0071161""(""cyanophycin synthetase activity (L-arginine-adding)"")|interpro:IPR044019|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR036565|interpro:IPR036615"	"refseq:NP_006014.2|ensembl:ENSG00000151465.14(gene)|ensembl:ENST00000281141.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0044183""(protein folding chaperone)|go:""GO:1905143""(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)|mint:O75794|rcsb pdb:8PHD|rcsb pdb:8PHV|panther:PTHR15323(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:G/7VoB+PXsUBR64uZvSZ3YEDOEY177416	rogid:VMzeYhMYvt77+83yeASAqju49xQ9606	intact-crc:CAC605063BD0F1AA|rigid:aYivIe/szNcLskoMxTgDntnMnN0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEQ5	uniprotkb:O75794	intact:EBI-2808269|uniprotkb:A0A0G2RQ71	intact:EBI-2808248|uniprotkb:Q14107|uniprotkb:Q5T0L9|uniprotkb:Q5T0L4|uniprotkb:Q5T0L7|uniprotkb:Q5T0L8|uniprotkb:A8JZZ7|uniprotkb:Q5T0L5|ensembl:ENSP00000281141.4	psi-mi:q5neq5_fratt(display_long)|uniprotkb:Polyphosphate kinase PPK2(gene name synonym)|uniprotkb:FTT_1564(locus name)	psi-mi:cd123_human(display_long)|uniprotkb:Cell division cycle protein 123 homolog(gene name synonym)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:C10orf7(gene name synonym)|uniprotkb:D123(gene name synonym)|uniprotkb:HT-1080(gene name synonym)|uniprotkb:PZ32(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808266|imex:IM-13779-1239	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016898(Polyphosphate kinase 2, predicted)|interpro:IPR022488|interpro:IPR022486|refseq:YP_170487.1|refseq:WP_003014894.1|interpro:IPR027417|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0046872""(metal ion binding)|rcsb pdb:4YEG|rcsb pdb:5LL0|rcsb pdb:5LLB|rcsb pdb:5LLF|mint:Q5NEQ5"	"refseq:NP_006014.2|ensembl:ENSG00000151465.14(gene)|ensembl:ENST00000281141.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0044183""(protein folding chaperone)|go:""GO:1905143""(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)|mint:O75794|rcsb pdb:8PHD|rcsb pdb:8PHV|panther:PTHR15323(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3hIShFXVmkZdI9gV6zbu32j30jM177416	rogid:VMzeYhMYvt77+83yeASAqju49xQ9606	intact-crc:6F1496063845D863|rigid:cl9RfW8TSVBuPuhiQ+2zv0AVuwc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6P2H3	uniprotkb:Q5NIN9	intact:EBI-2808308|uniprotkb:Q5VY68|uniprotkb:Q9H828|uniprotkb:Q9H6Q1|uniprotkb:Q5VY70|uniprotkb:Q9UF52|uniprotkb:D3DPK4|ensembl:ENSP00000252992.4|uniprotkb:B4DRL1|uniprotkb:F8W7K4	intact:EBI-2797260|uniprotkb:A0A0G2RMI5	psi-mi:cep85_human(display_long)|uniprotkb:CCDC21(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 21(gene name synonym)|uniprotkb:CEP85(gene name)|psi-mi:CEP85(display_short)	psi-mi:q5nin9_fratt(display_long)|uniprotkb:lysA1(gene name)|psi-mi:lysA1(display_short)|uniprotkb:FTT_0027c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808305|imex:IM-13779-1243	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001306873.1|refseq:NP_073615.2|refseq:NP_001268446.1|refseq:NP_001268447.1|ensembl:ENSG00000130695.16(gene)|ensembl:ENST00000252992.8(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0000922""(spindle pole)|go:""GO:0005730""(nucleolus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007099""(centriole replication)|go:""GO:0016477""(cell migration)|go:""GO:0042802""(identical protein binding)|go:""GO:0046602""(regulation of mitotic centrosome separation)|go:""GO:0098534""(centriole assembly)|interpro:IPR040210|mint:Q6P2H3|rcsb pdb:5OI7|rcsb pdb:5OID|panther:PTHR31075(orthology-group)"	"go:""GO:0008836""(diaminopimelate decarboxylase activity)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR022643|interpro:IPR022644|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|refseq:YP_169103.1|interpro:IPR029066|refseq:WP_003022882.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:akTkilY7AIoc1FtkiNFwz4oelvI9606	rogid:QY7TCwwQHpl28YxX5gZokSqUYFU177416	intact-crc:C17957CA0DD9D7CE|rigid:80WBfoIjWEs84PdFmKANhtJhjSk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGF9	uniprotkb:Q8N0Z3	intact:EBI-2796712|uniprotkb:A0A0G2RMW7	intact:EBI-2361917|uniprotkb:Q8WUX6|uniprotkb:D3DN72|ensembl:ENSP00000295872.4|intact:EBI-28978711	psi-mi:q5ngf9_fratt(display_long)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:FTT_0886(locus name)	psi-mi:spice_human(display_long)|uniprotkb:CCDC52(gene name synonym)|uniprotkb:SPICE(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 52(gene name synonym)|uniprotkb:Spindle and centriole-associated protein(gene name synonym)|uniprotkb:SPICE1(gene name)|psi-mi:SPICE1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808298|imex:IM-13779-1241	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|refseq:YP_169883.1|interpro:IPR027417|refseq:WP_003020876.1"	"refseq:NP_653319.1|ensembl:ENSG00000163611.11(gene)|ensembl:ENST00000295872.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005819""(spindle)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051301""(cell division)|go:""GO:0051310""(metaphase chromosome alignment)|go:""GO:0090307""(mitotic spindle assembly)|interpro:IPR031387|mint:Q8N0Z3|refseq:NP_001318007.1|refseq:XP_016861267.1|refseq:NP_001318008.1|panther:PTHR31167(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OSkw64bDGErXabpL9In6RSfdCEQ177416	rogid:Ogv5G3kQP2liovo9dVap83bif2M9606	intact-crc:4ABB4DBD52CC86BA|rigid:Sg65WLYok9s242ub+fPtihvlw6U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFQ6	uniprotkb:Q7L592	intact:EBI-2803494	intact:EBI-2555519|uniprotkb:Q9P1G3|uniprotkb:Q7Z399|ensembl:ENSP00000002125.4	psi-mi:q5nfq6_fratt(display_long)|uniprotkb:FTT_1170(locus name)	psi-mi:nduf7_human(display_long)|uniprotkb:NDUFAF7(gene name)|psi-mi:NDUFAF7(display_short)|uniprotkb:C2orf56(gene name synonym)|uniprotkb:NADH dehydrogenase [ubiquinone] complex I, assembly factor 7(gene name synonym)|uniprotkb:Protein midA homolog(gene name synonym)|uniprotkb:PRO1853(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808328|imex:IM-13779-1244	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:YP_170136.1|go:""GO:0016020""(membrane)|go:""GO:0036503""(ERAD pathway)|interpro:IPR050767"	"refseq:NP_001077415.1|refseq:NP_653337.1|ensembl:ENSG00000003509.16(gene)|ensembl:ENST00000002125.9(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0008469""(histone arginine N-methyltransferase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019918""(peptidyl-arginine methylation, to symmetrical-dimethyl arginine)|go:""GO:0032981""(mitochondrial respiratory chain complex I assembly)|go:""GO:0035243""(protein-arginine omega-N symmetric methyltransferase activity)|go:""GO:0035642""(histone H3R17 methyltransferase activity)|go:""GO:0044020""(histone H4R3 methyltransferase activity)|go:""GO:0062122""(histone H3K37 methyltransferase activity)|go:""GO:0070611""(histone H3R2 methyltransferase activity)|go:""GO:0140592""(histone H3R8 methyltransferase activity)|go:""GO:0140759""(histone H3K56 methyltransferase activity)|go:""GO:0140903""(histone H3R26 methyltransferase activity)|go:""GO:0140984""(histone H4K12 methyltransferase activity)|go:""GO:1990259""(histone H2A Q104 methyltransferase activity)|interpro:IPR003788(Protein of unknown function DUF185)|interpro:IPR029063|interpro:IPR038375|mint:Q7L592|reactome:R-HSA-6799198|panther:PTHR12049(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Rw7n2+NGU7uN8LMwBodXD4RI7s4177416	rogid:yPmuWj24WTnISoXS2kQzHLs/Sjs9606	intact-crc:FB376E9099F15764|rigid:QV4q4lfAIRyCQbdg13lJKMaTqC0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7L592	uniprotkb:Q5NGW2	intact:EBI-2555519|uniprotkb:Q9P1G3|uniprotkb:Q7Z399|ensembl:ENSP00000002125.4	intact:EBI-2796474|uniprotkb:A0A0G2RND5	psi-mi:nduf7_human(display_long)|uniprotkb:NDUFAF7(gene name)|psi-mi:NDUFAF7(display_short)|uniprotkb:C2orf56(gene name synonym)|uniprotkb:NADH dehydrogenase [ubiquinone] complex I, assembly factor 7(gene name synonym)|uniprotkb:Protein midA homolog(gene name synonym)|uniprotkb:PRO1853(orf name)	psi-mi:q5ngw2_fratt(display_long)|uniprotkb:FTT_0715(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808321|imex:IM-13779-1242	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001077415.1|refseq:NP_653337.1|ensembl:ENSG00000003509.16(gene)|ensembl:ENST00000002125.9(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0008469""(histone arginine N-methyltransferase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019918""(peptidyl-arginine methylation, to symmetrical-dimethyl arginine)|go:""GO:0032981""(mitochondrial respiratory chain complex I assembly)|go:""GO:0035243""(protein-arginine omega-N symmetric methyltransferase activity)|go:""GO:0035642""(histone H3R17 methyltransferase activity)|go:""GO:0044020""(histone H4R3 methyltransferase activity)|go:""GO:0062122""(histone H3K37 methyltransferase activity)|go:""GO:0070611""(histone H3R2 methyltransferase activity)|go:""GO:0140592""(histone H3R8 methyltransferase activity)|go:""GO:0140759""(histone H3K56 methyltransferase activity)|go:""GO:0140903""(histone H3R26 methyltransferase activity)|go:""GO:0140984""(histone H4K12 methyltransferase activity)|go:""GO:1990259""(histone H2A Q104 methyltransferase activity)|interpro:IPR003788(Protein of unknown function DUF185)|interpro:IPR029063|interpro:IPR038375|mint:Q7L592|reactome:R-HSA-6799198|panther:PTHR12049(orthology-group)"	"go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0004568""(chitinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR029070|refseq:YP_169730.1|interpro:IPR003610(Carbohydrate-binding family V/XII)|interpro:IPR011583(Chitinase II)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_003020524.1|interpro:IPR036116|interpro:IPR036573|interpro:IPR050314"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yPmuWj24WTnISoXS2kQzHLs/Sjs9606	rogid:hPHdF34TD5FCXE5bWyEmg/dd7sg177416	intact-crc:C0CC1F90988360DE|rigid:Cj2vCnjkimIV5fcA+D2VH2M03ds	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P25774	uniprotkb:Q5NF74	intact:EBI-2808345|uniprotkb:Q6FHS5|uniprotkb:Q9BUG3|uniprotkb:Q5T5I0|uniprotkb:D3DV05|uniprotkb:B4DWC9|ensembl:ENSP00000357981.3|ensembl:ENSP00000475176.2|ensembl:ENSP00000475557.2|ensembl:ENSP00000505359.1	intact:EBI-2796785|uniprotkb:A0A0G2RND4	psi-mi:cats_human(display_long)|uniprotkb:CTSS(gene name)|psi-mi:CTSS(display_short)	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808342|imex:IM-13779-1247	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004070.3|refseq:NP_001186668.1|ensembl:ENSG00000163131.12(gene)|ensembl:ENST00000368985.8(transcript)|ensembl:ENST00000472977.7(transcript)|ensembl:ENST00000607427.2(transcript)|ensembl:ENST00000681444.1(transcript)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006955""(immune response)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0010447""(response to acidic pH)|go:""GO:0016485""(protein processing)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030574""(collagen catabolic process)|go:""GO:0034769""(basement membrane disassembly)|go:""GO:0036021""(endolysosome lumen)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043236""(laminin binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048002""(antigen processing and presentation of peptide antigen)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0097067""(cellular response to thyroid hormone stimulus)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2001235""(positive regulation of apoptotic signaling pathway)|go:""GO:2001259""(positive regulation of cation channel activity)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR013201(Proteinase inhibitor I29, cathepsin propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|interpro:IPR039417|rcsb pdb:1GLO|rcsb pdb:1MS6|rcsb pdb:1NPZ|rcsb pdb:1NQC|rcsb pdb:2C0Y|rcsb pdb:2F1G|rcsb pdb:2FQ9|rcsb pdb:2FRA|rcsb pdb:2FRQ|rcsb pdb:2FT2|rcsb pdb:2FUD|rcsb pdb:2FYE|rcsb pdb:2G6D|rcsb pdb:2G7Y|rcsb pdb:2H7J|rcsb pdb:2HH5|rcsb pdb:2HHN|rcsb pdb:2HXZ|rcsb pdb:2OP3|rcsb pdb:2R9M|rcsb pdb:2R9N|rcsb pdb:2R9O|rcsb pdb:3IEJ|rcsb pdb:3N3G|rcsb pdb:3N4C|rcsb pdb:3OVX|rcsb pdb:4P6E|rcsb pdb:4P6G|rcsb pdb:5QBU|rcsb pdb:5QBV|rcsb pdb:5QBW|rcsb pdb:5QBX|rcsb pdb:5QBY|rcsb pdb:5QBZ|rcsb pdb:5QC0|rcsb pdb:5QC1|rcsb pdb:5QC2|rcsb pdb:5QC3|rcsb pdb:5QC4|rcsb pdb:5QC5|rcsb pdb:5QC6|rcsb pdb:5QC7|rcsb pdb:5QC8|rcsb pdb:5QC9|rcsb pdb:5QCA|rcsb pdb:5QCB|rcsb pdb:5QCC|rcsb pdb:5QCD|rcsb pdb:5QCE|rcsb pdb:5QCF|rcsb pdb:5QCG|rcsb pdb:5QCH|rcsb pdb:5QCI|rcsb pdb:5QCJ|rcsb pdb:6YYN|rcsb pdb:6YYO|rcsb pdb:6YYP|rcsb pdb:6YYQ|rcsb pdb:6YYR|rcsb pdb:8PI3|rcsb pdb:8RND|rcsb pdb:9GJ2|reactome:R-HSA-1236977|reactome:R-HSA-1474228|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|dip:DIP-61077N|panther:PTHR12411(orthology-group)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/47OYPCznvm6Z1si/zQXey+Nk0U9606	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	intact-crc:222ED7693ACC9836|rigid:NzfL113FLvp76VUuL96k+x5m7Wc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14511	uniprotkb:Q5NHZ4	intact:EBI-2108053|uniprotkb:Q5T9R4|uniprotkb:A8K9G7|uniprotkb:G5E9Y9|uniprotkb:A8MSJ9|uniprotkb:Q5XKI0|ensembl:ENSP00000368759.5|intact:EBI-28980032	intact:EBI-2798091	psi-mi:casl_human(display_long)|uniprotkb:NEDD9(gene name)|psi-mi:NEDD9(display_short)|uniprotkb:CASL(gene name synonym)|uniprotkb:CRK-associated substrate-related protein(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 9(gene name synonym)|uniprotkb:Cas scaffolding protein family member 2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-12(gene name synonym)	psi-mi:syv_fratt(display_long)|uniprotkb:valS(gene name)|psi-mi:valS(display_short)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0299(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808363|imex:IM-13779-1248	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006394.1|refseq:NP_892011.2|refseq:NP_001135865.1|refseq:NP_001257962.1|panther:PTHR10654(orthology-group)|ensembl:ENSG00000111859.17(gene)|ensembl:ENST00000379446.10(transcript)|go:""GO:0000922""(spindle pole)|go:""GO:0001772""(immunological synapse)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007611""(learning or memory)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030027""(lamellipodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0036064""(ciliary basal body)|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051301""(cell division)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0061523""(cilium disassembly)|go:""GO:0072686""(mitotic spindle)|go:""GO:0097021""(lymphocyte migration into lymphoid organs)|go:""GO:0140131""(positive regulation of lymphocyte chemotaxis)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902952""(positive regulation of dendritic spine maintenance)|go:""GO:1903829""(positive regulation of protein localization)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000522""(positive regulation of immunological synapse formation)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR035746|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:Q14511|rcsb pdb:2L81|rcsb pdb:5X3S"	"go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004832""(valine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006438""(valyl-tRNA aminoacylation)|refseq:YP_169348.1|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR019499|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR033705|refseq:WP_003021639.1|interpro:IPR037118"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3PsYJXDgAihLYOOwKMBtDhQZQkU9606	rogid:x/UHW8BtUK4O+DP24Ws5NMlvUpw177416	intact-crc:B081AF64EF34A42F|rigid:09ffV08DdM0EoVwjTR+WTFthEzw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P47755	uniprotkb:Q5NHX0	intact:EBI-762451|ensembl:ENSP00000354947.2|uniprotkb:B4DG50	intact:EBI-2799263	psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short)	psi-mi:efg_fratt(display_long)|uniprotkb:FTT_0323(locus name)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808335|imex:IM-13779-1245	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006127.1|ensembl:ENSG00000198898.16(gene)|ensembl:ENST00000361183.8(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|panther:PTHR10653(orthology-group)"	"refseq:YP_169372.1|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR031157|refseq:WP_003028885.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|interpro:IPR047872"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606	rogid:hULyXsLqQVOFqECbDOTlNV2kzrY177416	intact-crc:5809E60558038965|rigid:nQgdMcAGnlZG7VP3b0QdBu/HSVo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF37	uniprotkb:P04040	intact:EBI-2798724	intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052.4	psi-mi:syp_fratt(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1412(locus name)	psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808356|imex:IM-13779-1246	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044140|refseq:YP_170355.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|interpro:IPR033730|refseq:WP_003022224.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR045864|interpro:IPR050062"	"ensembl:ENSG00000121691.7(gene)|ensembl:ENST00000241052.5(transcript)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001657""(ureteric bud development)|go:""GO:0001666""(response to hypoxia)|go:""GO:0004046""(aminoacylase activity)|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0009060""(aerobic respiration)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009642""(response to light intensity)|go:""GO:0009650""(UV protection)|go:""GO:0010193""(response to ozone)|go:""GO:0010288""(response to lead ion)|go:""GO:0014823""(response to activity)|go:""GO:0014854""(response to inactivity)|go:""GO:0016020""(membrane)|go:""GO:0016209""(antioxidant activity)|go:""GO:0016684""(oxidoreductase activity, acting on peroxide as acceptor)|go:""GO:0019899""(enzyme binding)|go:""GO:0020027""(hemoglobin metabolic process)|go:""GO:0020037""(heme binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032868""(response to insulin)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033189""(response to vitamin A)|go:""GO:0033197""(response to vitamin E)|go:""GO:0033591""(response to L-ascorbic acid)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045471""(response to ethanol)|go:""GO:0046686""(response to cadmium ion)|go:""GO:0046872""(metal ion binding)|go:""GO:0050661""(NADP binding)|go:""GO:0051781""(positive regulation of cell division)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0062151""(catalase complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070542""(response to fatty acid)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072722""(response to amitrole)|go:""GO:0080184""(response to phenylpropanoid)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|rcsb pdb:7P8W|rcsb pdb:7VD9|rcsb pdb:8EL9|rcsb pdb:8HID|rcsb pdb:8PVD|rcsb pdb:8SGV|rcsb pdb:8WZH|rcsb pdb:8WZJ|rcsb pdb:8WZK|rcsb pdb:8WZM|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017|reactome:R-HSA-9841251|refseq:NP_001743.1|efo:""Orphanet:926""|panther:PTHR11465(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6/QkU5JRWJEBZMwaR9J83no0ffk177416	rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606	intact-crc:68396E8910E4057F|rigid:D28PugcjTb9KwTjPNUjiCifhgOU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27824	uniprotkb:Q5NEC0	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000247461.4|ensembl:ENSP00000391646.2|ensembl:ENSP00000421434.2|ensembl:ENSP00000421813.2|ensembl:ENSP00000424063.1|ensembl:ENSP00000424745.2|ensembl:ENSP00000491760.1|ensembl:ENSP00000492372.1|ensembl:ENSP00000492868.1|ensembl:ENSP00000505013.1|ensembl:ENSP00000505202.1|ensembl:ENSP00000505526.1|ensembl:ENSP00000505960.1|ensembl:ENSP00000506003.1|ensembl:ENSP00000506021.1|ensembl:ENSP00000506061.1|ensembl:ENSP00000506078.1|ensembl:ENSP00000506509.1|ensembl:ENSP00000506568.1|ensembl:ENSP00000506583.1|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808413|imex:IM-13779-1251	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|ensembl:ENSG00000127022.16(gene)|ensembl:ENSG00000283777.2(gene)|ensembl:ENST00000247461.9(transcript)|ensembl:ENST00000452673.6(transcript)|ensembl:ENST00000502296.6(transcript)|ensembl:ENST00000504734.5(transcript)|ensembl:ENST00000509563.2(transcript)|ensembl:ENST00000513246.6(transcript)|ensembl:ENST00000638425.1(transcript)|ensembl:ENST00000638706.2(transcript)|ensembl:ENST00000639938.1(transcript)|ensembl:ENST00000680013.1(transcript)|ensembl:ENST00000680042.1(transcript)|ensembl:ENST00000680092.1(transcript)|ensembl:ENST00000680618.1(transcript)|ensembl:ENST00000681072.1(transcript)|ensembl:ENST00000681168.1(transcript)|ensembl:ENST00000681476.1(transcript)|ensembl:ENST00000681674.1(transcript)|ensembl:ENST00000681712.1(transcript)|ensembl:ENST00000681733.1(transcript)|ensembl:ENST00000681903.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006457""(protein folding)|go:""GO:0009306""(protein secretion)|go:""GO:0016020""(membrane)|go:""GO:0019082""(viral protein processing)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033162""(melanosome membrane)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0036503""(ERAD pathway)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0044322""(endoplasmic reticulum quality control compartment)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098793""(presynapse)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|dip:DIP-457N|panther:PTHR11073(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:0461E83AE3E7FAE5|rigid:ybfhDBpG+J7xzKD7DNHkTRoxK88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01518	uniprotkb:Q5NFJ3	intact:EBI-2808398|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1|ensembl:ENSP00000361878.2|ensembl:ENSP00000361883.3|ensembl:ENSP00000361891.3	intact:EBI-2807437	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:glya_fratt(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:FTT_1241(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808406|imex:IM-13779-1253	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_005270425.1|ensembl:ENSG00000131236.18(gene)|ensembl:ENST00000372792.7(transcript)|ensembl:ENST00000372797.7(transcript)|ensembl:ENST00000372805.8(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001667""(ameboidal-type cell migration)|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007165""(signal transduction)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0019933""(cAMP-mediated signaling)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098885""(modification of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR036222|interpro:IPR036223|interpro:IPR053950|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|dip:DIP-62063N|panther:PTHR10652(orthology-group)"	"interpro:IPR049943|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR019798|refseq:YP_170199.1|go:""GO:0004372""(glycine hydroxymethyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0019264""(glycine biosynthetic process from serine)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0035999""(tetrahydrofolate interconversion)|interpro:IPR039429|refseq:WP_003021543.1"	"psi-mi:""MI:0469""(intact)"	crc64:7789D1FAC0D1AB7B	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rogid:YGV3lD5dnE8X8rx9qJdzXtxEdhM177416	intact-crc:CCE609731C5880EC|rigid:2MF6nbh52kMZi6PhDv7K8fTPJDI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGF9	uniprotkb:Q14444	intact:EBI-2796712|uniprotkb:A0A0G2RMW7	intact:EBI-1047080|uniprotkb:Q15074|intact:EBI-1171814|uniprotkb:Q6IMN4|uniprotkb:A6NMY7|uniprotkb:Q6IMN7|uniprotkb:Q9BV09|intact:EBI-2562858|ensembl:ENSP00000340329.4|ensembl:ENSP00000434150.1|intact:EBI-3449178|uniprotkb:D3DR06	psi-mi:q5ngf9_fratt(display_long)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:FTT_0886(locus name)	psi-mi:capr1_human(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808391|imex:IM-13779-1250	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|refseq:YP_169883.1|interpro:IPR027417|refseq:WP_003020876.1"	"ensembl:ENSG00000135387.21(gene)|ensembl:ENST00000341394.9(transcript)|ensembl:ENST00000532820.5(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007416""(synapse assembly)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030425""(dendrite)|go:""GO:0031252""(cell leading edge)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0045202""(synapse)|go:""GO:0048699""(generation of neurons)|go:""GO:0050775""(positive regulation of dendrite morphogenesis)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0106288""(regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|interpro:IPR022070|interpro:IPR028816|interpro:IPR041637|mint:Q14444|rcsb pdb:4WBE|rcsb pdb:4WBP|rcsb pdb:6TA7|rcsb pdb:7XHG|rcsb pdb:8TH7|refseq:NP_005889.3|refseq:NP_976240.1|refseq:XP_016873238.1|efo:""Orphanet:528084""|panther:PTHR22922(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OSkw64bDGErXabpL9In6RSfdCEQ177416	rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606	intact-crc:E4E943518C38E4C6|rigid:K+5JhjM55SnkMX1hJL3iUmHd6hs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEX4	uniprotkb:Q9Y2G2	intact:EBI-2800250|uniprotkb:A0A0G2RPH4	intact:EBI-2808370|uniprotkb:Q96P82|uniprotkb:Q6PGP8|uniprotkb:B7Z496|ensembl:ENSP00000375767.3|ensembl:ENSP00000428883.1|ensembl:ENSP00000499211.1|uniprotkb:B7Z4A2|uniprotkb:G3XAM9|uniprotkb:B5KVR6|uniprotkb:E9PEM7|uniprotkb:B5KVR8|uniprotkb:E5RFV9	psi-mi:q5nex4_fratt(display_long)|uniprotkb:lpd(gene name)|psi-mi:lpd(display_short)|uniprotkb:FTT_1483c(locus name)	psi-mi:card8_human(display_long)|uniprotkb:CARD8(gene name)|psi-mi:CARD8(display_short)|uniprotkb:KIAA0955(gene name synonym)|uniprotkb:NDPP1(gene name synonym)|uniprotkb:CARD-inhibitor of NF-kappa-B-activating ligand(gene name synonym)|uniprotkb:DACAR(gene name synonym)|uniprotkb:Tumor up-regulated CARD-containing antagonist of CASP9(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808377|imex:IM-13779-1249	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|refseq:YP_170418.1|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_003022339.1|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR036188|interpro:IPR050151"	"refseq:XP_011524943.1|refseq:XP_011524944.1|refseq:XP_011524945.1|refseq:XP_011524946.1|refseq:XP_011524952.1|refseq:NP_001171833.1|refseq:XP_006723173.1|refseq:NP_001171829.1|refseq:NP_001171830.1|refseq:NP_001171831.1|refseq:NP_001171832.1|refseq:NP_055774.2|ensembl:ENSG00000105483.18(gene)|ensembl:ENST00000391898.7(transcript)|ensembl:ENST00000519940.6(transcript)|ensembl:ENST00000651546.1(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006954""(inflammatory response)|go:""GO:0008233""(peptidase activity)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032089""(NACHT domain binding)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0050700""(CARD domain binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0072559""(NLRP3 inflammasome complex)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097264""(self proteolysis)|go:""GO:0097340""(obsolete inhibition of cysteine-type endopeptidase activity)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140608""(cysteine-type endopeptidase activator activity)|go:""GO:0140633""(CARD8 inflammasome complex assembly)|go:""GO:0140634""(CARD8 inflammasome complex)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|interpro:IPR051249|mint:Q9Y2G2|rcsb pdb:4IKM|rcsb pdb:6K9F|rcsb pdb:6XKJ|rcsb pdb:7JKQ|rcsb pdb:7JN7|reactome:R-HSA-111458|reactome:R-HSA-9627069|refseq:XP_006723154.1|refseq:XP_006723155.1|refseq:XP_006723156.1|refseq:XP_006723158.1|refseq:XP_006723159.1|refseq:XP_006723160.1|refseq:XP_006723167.1|refseq:XP_006723169.1|refseq:XP_006723172.1|refseq:XP_016881972.1|refseq:XP_016881979.1|refseq:XP_016881987.1|panther:PTHR46985(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M7P/eSKN5XPGALvQBQLWvlqQ7fY177416	rogid:WCpalGD3/kZFOTQQNc42fKReKAA9606	intact-crc:A47E75D2CD2B7E3A|rigid:cAKrJ33VtEMx/t6L+MIvzwWB1XI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID9	uniprotkb:Q9Y2G2	intact:EBI-2798201	intact:EBI-2808370|uniprotkb:Q96P82|uniprotkb:Q6PGP8|uniprotkb:B7Z496|ensembl:ENSP00000375767.3|ensembl:ENSP00000428883.1|ensembl:ENSP00000499211.1|uniprotkb:B7Z4A2|uniprotkb:G3XAM9|uniprotkb:B5KVR6|uniprotkb:E9PEM7|uniprotkb:B5KVR8|uniprotkb:E5RFV9	psi-mi:eftu_fratt(display_long)|uniprotkb:FTT_0137(locus name)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)	psi-mi:card8_human(display_long)|uniprotkb:CARD8(gene name)|psi-mi:CARD8(display_short)|uniprotkb:KIAA0955(gene name synonym)|uniprotkb:NDPP1(gene name synonym)|uniprotkb:CARD-inhibitor of NF-kappa-B-activating ligand(gene name synonym)|uniprotkb:DACAR(gene name synonym)|uniprotkb:Tumor up-regulated CARD-containing antagonist of CASP9(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808384|imex:IM-13779-1252	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0097216""(guanosine tetraphosphate binding)|refseq:YP_169203.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR033720|interpro:IPR031157|refseq:WP_003028672.1|interpro:IPR041709|interpro:IPR050055"	"refseq:XP_011524943.1|refseq:XP_011524944.1|refseq:XP_011524945.1|refseq:XP_011524946.1|refseq:XP_011524952.1|refseq:NP_001171833.1|refseq:XP_006723173.1|refseq:NP_001171829.1|refseq:NP_001171830.1|refseq:NP_001171831.1|refseq:NP_001171832.1|refseq:NP_055774.2|ensembl:ENSG00000105483.18(gene)|ensembl:ENST00000391898.7(transcript)|ensembl:ENST00000519940.6(transcript)|ensembl:ENST00000651546.1(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006954""(inflammatory response)|go:""GO:0008233""(peptidase activity)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032089""(NACHT domain binding)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0050700""(CARD domain binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0072559""(NLRP3 inflammasome complex)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097264""(self proteolysis)|go:""GO:0097340""(obsolete inhibition of cysteine-type endopeptidase activity)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140608""(cysteine-type endopeptidase activator activity)|go:""GO:0140633""(CARD8 inflammasome complex assembly)|go:""GO:0140634""(CARD8 inflammasome complex)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|interpro:IPR051249|mint:Q9Y2G2|rcsb pdb:4IKM|rcsb pdb:6K9F|rcsb pdb:6XKJ|rcsb pdb:7JKQ|rcsb pdb:7JN7|reactome:R-HSA-111458|reactome:R-HSA-9627069|refseq:XP_006723154.1|refseq:XP_006723155.1|refseq:XP_006723156.1|refseq:XP_006723158.1|refseq:XP_006723159.1|refseq:XP_006723160.1|refseq:XP_006723167.1|refseq:XP_006723169.1|refseq:XP_006723172.1|refseq:XP_016881972.1|refseq:XP_016881979.1|refseq:XP_016881987.1|panther:PTHR46985(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h5xJZCtwL77bt8cg/p85MmX1c+E177416	rogid:WCpalGD3/kZFOTQQNc42fKReKAA9606	intact-crc:75BC39D2CEE5DF08|rigid:he2+y8FHDnKW7C6656UHzLUfkyc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62158	uniprotkb:Q5NIP5	intact:EBI-397435|uniprotkb:P02593|uniprotkb:Q53S29|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	intact:EBI-2797625	psi-mi:calm_human(display_short)|psi-mi:P62158(display_long)|uniprotkb:CALM1(gene name)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:gatb_fratt(display_long)|uniprotkb:FTT_0021(locus name)|uniprotkb:gatB(gene name)|psi-mi:gatB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808420|imex:IM-13779-1255	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:1304""(molecule set)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:""GO:0002027""(regulation of heart rate)|go:""GO:0005513""(detection of calcium ion)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0030017""(sarcomere)|go:""GO:0030801""(obsolete positive regulation of cyclic nucleotide metabolic process)|go:""GO:0032516""(obsolete positive regulation of phosphoprotein phosphatase activity)|go:""GO:0035307""(obsolete positive regulation of protein dephosphorylation)|go:""GO:0051343""(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005876""(spindle microtubule)|go:""GO:0000922""(spindle pole)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0006936""(muscle contraction)|go:""GO:0060315""(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0002576""(platelet degranulation)|go:""GO:0060316""(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0050999""(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:""GO:0010801""(negative regulation of peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031954""(positive regulation of protein autophosphorylation)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0000165""(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:5COC|go:""GO:0021762""(substantia nigra development)|go:""GO:0070062""(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|rcsb pdb:4GOW|rcsb pdb:4Q57|go:""GO:0043647""(inositol phosphate metabolic process)|go:""GO:0022400""(regulation of opsin-mediated signaling pathway)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0005576""(extracellular region)|go:""GO:0031997""(obsolete N-terminal myristoylation domain binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0010880""(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031432""(titin binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051592""(response to calcium ion)|go:""GO:0055117""(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:""GO:0005088""|go:""GO:0007223""(Wnt signaling pathway, calcium modulating pathway)|go:""GO:0008440""(inositol-1,4,5-trisphosphate 3-kinase activity)|go:""GO:0015276""(ligand-gated monoatomic ion channel activity)|go:""GO:0005634""(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:4UMO|rcsb pdb:4V0C|go:""GO:0031982""(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|refseq:NP_001292555.1|rcsb pdb:4OVN|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|rcsb pdb:5DBR|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0001975""(response to amphetamine)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0030235""(nitric-oxide synthase regulator activity)|go:""GO:0030426""(growth cone)|go:""GO:0051000""(positive regulation of nitric-oxide synthase activity)|go:""GO:0051412""(response to corticosterone)|go:""GO:1901841""(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:""GO:0032991""(protein-containing complex)|go:""GO:0006479""(protein methylation)|go:""GO:0014069""(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0043388""(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:""GO:0034704""(calcium channel complex)|go:""GO:0010856""(adenylate cyclase activator activity)|go:""GO:0051186""(obsolete cofactor metabolic process)|go:""GO:0075206""(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:""GO:0060314""(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:""GO:1902494""(catalytic complex)|go:""GO:0043234""|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0030819""(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:""GO:0019722""(calcium-mediated signaling)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:""GO:0005623""(obsolete cell)|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|rcsb pdb:6HR1|rcsb pdb:6OS4|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0016032""(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O"	"go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0050566""(""asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0070681""(glutaminyl-tRNAGln biosynthesis via transamidation)|interpro:IPR017959|interpro:IPR006075(GatB N-terminal region)|interpro:IPR018027|interpro:IPR003789(GatB/Yqey)|interpro:IPR023168|interpro:IPR004413(""Glutamyl-tRNA(Gln) amidotransferase B subunit"")|interpro:IPR017958|refseq:YP_169097.1|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|refseq:WP_003017411.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	-	rogid:MULE4syC9yNG02pvDj3Le0UVDRw177416	intact-crc:28C476C43CDC1CBA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P1Z2	uniprotkb:Q5NI33	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960.1	intact:EBI-2800112|uniprotkb:A0A0G2RMA5	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:q5ni33_fratt(display_long)|uniprotkb:FTT_0257(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808434|imex:IM-13779-1256	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137154.1|refseq:NP_065949.1|ensembl:ENSG00000012822.16(gene)|ensembl:ENST00000550804.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030518""(nuclear receptor-mediated steroid hormone signaling pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|interpro:IPR051002|mint:Q9P1Z2|refseq:XP_016875196.1|dip:DIP-47322N|panther:PTHR31915(orthology-group)"	"refseq:YP_169309.1|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0006402""(mRNA catabolic process)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:WP_003021737.1|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR036388|interpro:IPR050180"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	rogid:T86jKHSo3mAW/ak8vzq3vAvG0j0177416	intact-crc:69B50EAE5D05F19B|rigid:+MSssOK4m2TuXebjH5ub5rniaE8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEX4	uniprotkb:Q13137	intact:EBI-2800250|uniprotkb:A0A0G2RPH4	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5|ensembl:ENSP00000258947.3	psi-mi:q5nex4_fratt(display_long)|uniprotkb:lpd(gene name)|psi-mi:lpd(display_short)|uniprotkb:FTT_1483c(locus name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808427|imex:IM-13779-1254	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|refseq:YP_170418.1|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_003022339.1|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR036188|interpro:IPR050151"	"refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|refseq:NP_001248324.1|ensembl:ENSG00000136436.16(gene)|ensembl:ENST00000258947.8(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005776""(autophagosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016032""(viral process)|go:""GO:0016605""(PML body)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034341""(response to type II interferon)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0098792""(xenophagy)|go:""GO:1901098""(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|interpro:IPR051002|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|rcsb pdb:7EAA|dip:DIP-57534N|panther:PTHR31915(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	crc64:609B121DA1A9DCB8	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:M7P/eSKN5XPGALvQBQLWvlqQ7fY177416	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:470730F9C920D41B|rigid:mAZbB/4HQTCLfKVVKNTs1HDIIUw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86VB7	uniprotkb:Q4VP87	intact:EBI-2808455|uniprotkb:Q07901|uniprotkb:Q07898|uniprotkb:Q2VLH7|uniprotkb:Q07899|uniprotkb:Q07900|uniprotkb:C9JIG2|ensembl:ENSP00000352071.4	intact:EBI-2796861	psi-mi:c163a_human(display_long)|uniprotkb:CD163(gene name)|psi-mi:CD163(display_short)|uniprotkb:M130(gene name synonym)|uniprotkb:Hemoglobin scavenger receptor(gene name synonym)	psi-mi:q4vp87_fratl(display_long)|uniprotkb:FTT0445(orf name)|uniprotkb:uup(gene name)|psi-mi:uup(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808465|imex:IM-13779-1258	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004235.4|refseq:NP_981961.2|ensembl:ENSG00000177575.13(gene)|ensembl:ENST00000359156.8(transcript)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0097110""(scaffold protein binding)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR036772|mint:Q86VB7|reactome:R-HSA-2168880|reactome:R-HSA-9662834|refseq:XP_016875720.1|panther:PTHR19331(orthology-group)"	"go:""GO:0005524""(ATP binding)|interpro:IPR027417|interpro:IPR032781|interpro:IPR051309"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:irBZJ2L9f0SE5YDTxaxokN+J7mg9606	rogid:+Qbmzj8eW72wb4LBUxcHkhpPQRE119856	intact-crc:5C3807C4F36FA8FF|rigid:/V1Ij4Ly5bmCzT1HHPpNjXzsZT4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99622	uniprotkb:Q5NI67	intact:EBI-2808472|uniprotkb:B2R4Q6|ensembl:ENSP00000229281.5|ensembl:ENSP00000440602.1	intact:EBI-2797389|uniprotkb:A0A0G2RMC4	psi-mi:c10_human(display_long)|uniprotkb:C12orf57(gene name)|psi-mi:C12orf57(display_short)|uniprotkb:C10(gene name synonym)	psi-mi:q5ni67_fratt(display_long)|uniprotkb:FTT_0220c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808477|imex:IM-13779-1260	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111678.11(gene)|ensembl:ENST00000229281.6(transcript)|ensembl:ENST00000545581.5(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0009791""(post-embryonic development)|go:""GO:0014819""(regulation of skeletal muscle contraction)|go:""GO:0016607""(nuclear speck)|go:""GO:0021540""(corpus callosum morphogenesis)|go:""GO:0021678""(third ventricle development)|go:""GO:0036343""(psychomotor behavior)|go:""GO:0048593""(camera-type eye morphogenesis)|go:""GO:0050890""(cognition)|interpro:IPR026317|refseq:NP_001288763.1|refseq:NP_612434.1|efo:""Orphanet:1777""|panther:PTHR13463(orthology-group)"	refseq:YP_169275.1|refseq:WP_003017784.1|interpro:IPR038078|interpro:IPR052912	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RQA3V8/ja1T1aBhtzEYvka2r7iQ9606	rogid:6JzFMA+xK04alHAUXqNLNh9+UCU177416	intact-crc:39BC54D545CFF860|rigid:7ZMgzQOpMlNt4abw7IkXuQv48TQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y5P4	uniprotkb:Q5NIG1	intact:EBI-739994|uniprotkb:Q96Q85|uniprotkb:Q96Q88|uniprotkb:Q9H2S7|uniprotkb:Q9H2S8|uniprotkb:Q53YV1|uniprotkb:Q53YV2|uniprotkb:A8K7S2|uniprotkb:B3KUB7|ensembl:ENSP00000261415.8|ensembl:ENSP00000494110.2|ensembl:ENSP00000495760.1	intact:EBI-2799910|uniprotkb:A0A0G2RM79	psi-mi:cert_human(display_long)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym)	psi-mi:q5nig1_fratt(display_long)|uniprotkb:polA(gene name)|psi-mi:polA(display_short)|uniprotkb:FTT_0111(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808441|imex:IM-13779-1257	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000113163.19(gene)|ensembl:ENST00000261415.12(transcript)|ensembl:ENST00000643780.2(transcript)|ensembl:ENST00000644072.2(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0006936""(muscle contraction)|go:""GO:0006955""(immune response)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007165""(signal transduction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016301""(kinase activity)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035621""(ER to Golgi ceramide transport)|go:""GO:0035627""(ceramide transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097001""(ceramide binding)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:0120012""(intermembrane sphingolipid transfer)|go:""GO:0120017""(ceramide transfer activity)|go:""GO:1902387""(ceramide 1-phosphate binding)|go:""GO:1902388""(ceramide 1-phosphate transfer activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002913(Lipid-binding START)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023393|interpro:IPR041952|interpro:IPR051213|mint:Q9Y5P4|rcsb pdb:2E3M|rcsb pdb:2E3N|rcsb pdb:2E3O|rcsb pdb:2E3P|rcsb pdb:2E3Q|rcsb pdb:2E3R|rcsb pdb:2E3S|rcsb pdb:2RSG|rcsb pdb:2Z9Y|rcsb pdb:2Z9Z|rcsb pdb:3H3Q|rcsb pdb:3H3R|rcsb pdb:3H3S|rcsb pdb:3H3T|rcsb pdb:4HHV|rcsb pdb:5JJD|rcsb pdb:5ZYG|rcsb pdb:5ZYH|rcsb pdb:5ZYI|rcsb pdb:5ZYJ|rcsb pdb:5ZYK|rcsb pdb:5ZYL|rcsb pdb:5ZYM|rcsb pdb:6IEZ|rcsb pdb:6IF0|rcsb pdb:6J0O|rcsb pdb:6J81|reactome:R-HSA-1660661|refseq:NP_001123577.1|refseq:NP_005704.1|refseq:NP_112729.1|refseq:XP_006714576.1|refseq:XP_016864408.1|panther:PTHR10219(orthology-group)"	"refseq:YP_169181.1|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR020046|interpro:IPR020045|interpro:IPR002421(5'-3' exonuclease)|interpro:IPR019760|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR018320|interpro:IPR002298(DNA polymerase A)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006302""(double-strand break repair)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0008409""(5'-3' exonuclease activity)|interpro:IPR029060|refseq:WP_003019852.1|interpro:IPR036279|interpro:IPR036397|interpro:IPR043502"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AohUpOJQHInz8f5bKv9/Xb5K+/Y9606	rogid:i8oe3SbGM1jV9pBfqQP0T5cI+MQ177416	intact-crc:F96F2F01E4934141|rigid:DrwbknfpQa1+95WKhcNuE6Usnac	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y5P4	uniprotkb:Q5NFQ6	intact:EBI-739994|uniprotkb:Q96Q85|uniprotkb:Q96Q88|uniprotkb:Q9H2S7|uniprotkb:Q9H2S8|uniprotkb:Q53YV1|uniprotkb:Q53YV2|uniprotkb:A8K7S2|uniprotkb:B3KUB7|ensembl:ENSP00000261415.8|ensembl:ENSP00000494110.2|ensembl:ENSP00000495760.1	intact:EBI-2803494	psi-mi:cert_human(display_long)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym)	psi-mi:q5nfq6_fratt(display_long)|uniprotkb:FTT_1170(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808448|imex:IM-13779-1259	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000113163.19(gene)|ensembl:ENST00000261415.12(transcript)|ensembl:ENST00000643780.2(transcript)|ensembl:ENST00000644072.2(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0006936""(muscle contraction)|go:""GO:0006955""(immune response)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007165""(signal transduction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016301""(kinase activity)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035621""(ER to Golgi ceramide transport)|go:""GO:0035627""(ceramide transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097001""(ceramide binding)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:0120012""(intermembrane sphingolipid transfer)|go:""GO:0120017""(ceramide transfer activity)|go:""GO:1902387""(ceramide 1-phosphate binding)|go:""GO:1902388""(ceramide 1-phosphate transfer activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002913(Lipid-binding START)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023393|interpro:IPR041952|interpro:IPR051213|mint:Q9Y5P4|rcsb pdb:2E3M|rcsb pdb:2E3N|rcsb pdb:2E3O|rcsb pdb:2E3P|rcsb pdb:2E3Q|rcsb pdb:2E3R|rcsb pdb:2E3S|rcsb pdb:2RSG|rcsb pdb:2Z9Y|rcsb pdb:2Z9Z|rcsb pdb:3H3Q|rcsb pdb:3H3R|rcsb pdb:3H3S|rcsb pdb:3H3T|rcsb pdb:4HHV|rcsb pdb:5JJD|rcsb pdb:5ZYG|rcsb pdb:5ZYH|rcsb pdb:5ZYI|rcsb pdb:5ZYJ|rcsb pdb:5ZYK|rcsb pdb:5ZYL|rcsb pdb:5ZYM|rcsb pdb:6IEZ|rcsb pdb:6IF0|rcsb pdb:6J0O|rcsb pdb:6J81|reactome:R-HSA-1660661|refseq:NP_001123577.1|refseq:NP_005704.1|refseq:NP_112729.1|refseq:XP_006714576.1|refseq:XP_016864408.1|panther:PTHR10219(orthology-group)"	"interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:YP_170136.1|go:""GO:0016020""(membrane)|go:""GO:0036503""(ERAD pathway)|interpro:IPR050767"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AohUpOJQHInz8f5bKv9/Xb5K+/Y9606	rogid:Rw7n2+NGU7uN8LMwBodXD4RI7s4177416	intact-crc:52A0F001E501BBAA|rigid:Ttan4d9Rzaa+k6DU0r5J3TS8vBo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14692	uniprotkb:Q5NG53	intact:EBI-2513630|uniprotkb:Q86XJ9|uniprotkb:Q5QPT5|ensembl:ENSP00000363642.4	intact:EBI-2799349	psi-mi:bms1_human(display_long)|uniprotkb:BMS1(gene name)|psi-mi:BMS1(display_short)|uniprotkb:BMS1L(gene name synonym)|uniprotkb:KIAA0187(gene name synonym)|uniprotkb:Ribosome assembly protein BMS1 homolog(gene name synonym)	psi-mi:syfa_fratt(display_long)|uniprotkb:pheS(gene name)|psi-mi:pheS(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:FTT_1003c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808525|imex:IM-13779-1263	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165733.8(gene)|ensembl:ENST00000374518.6(transcript)|go:""GO:0000462""(""maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0000479""(""endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0003723""(RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0032040""(small-subunit processome)|go:""GO:0034511""(U3 snoRNA binding)|go:""GO:0042274""(ribosomal small subunit biogenesis)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR027417|interpro:IPR030387|interpro:IPR037875|interpro:IPR039761|mint:Q14692|rcsb pdb:7MQ9|rcsb pdb:7MQA|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_055568.3|refseq:XP_005271903.1|refseq:XP_011538704.1|efo:""Orphanet:1114""|panther:PTHR12858(orthology-group)"	"interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR004188(Phenylalanyl-tRNA synthetase, class II, N-terminal)|interpro:IPR022911|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR010978(tRNA-binding arm)|refseq:YP_169989.1|go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004826""(phenylalanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006432""(phenylalanyl-tRNA aminoacylation)|refseq:WP_003021092.1|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9sd7sK6/Ue4DgLRT+j9Iw0+8om09606	rogid:Hq8kBVM9QQ3QfPD8XLRkZND+i8Q177416	intact-crc:752F20152766F2E7|rigid:svsIJd0zhZWeLMVOqhs+qkoUyPA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5VXM9	uniprotkb:Q5NF53	intact:EBI-2808505|ensembl:ENSP00000357857.5	intact:EBI-2797592|uniprotkb:A0A0G2RMJ2	psi-mi:q5vxm9_human(display_long)|uniprotkb:RPF2(gene name)|psi-mi:RPF2(display_short)	psi-mi:q5nf53_fratt(display_long)|uniprotkb:recB(gene name)|psi-mi:recB(display_short)|uniprotkb:Exonuclease V subunit RecB(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecB(gene name synonym)|uniprotkb:FTT_1394c(locus name)|uniprotkb:DNA 3'-5' helicase subunit RecB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808502|imex:IM-13779-1262	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000197498.13(gene)|ensembl:ENST00000368864.8(transcript)|go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000470""(maturation of LSU-rRNA)|go:""GO:0005730""(nucleolus)|go:""GO:0019843""(rRNA binding)|interpro:IPR039770"	"go:""GO:0000287""(magnesium ion binding)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR004586(Exodeoxyribonuclease V, beta subunit)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|refseq:YP_170339.1|interpro:IPR027417|refseq:WP_003022196.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DgoPWJc4UFEUze6Ltqhp2PivaWY9606	rogid:ii9dJldcaJ9ed2JkD66pMgtmBlQ177416	intact-crc:3FC0948A25E957D6|rigid:oASE0ilnsjk+3fi8Rlbc/XX3qnw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC8	uniprotkb:Q9ULD4	intact:EBI-2808513|uniprotkb:A0A0G2RP13	intact:EBI-1753470|uniprotkb:A6NJE2|uniprotkb:Q5R3K8|ensembl:ENSP00000350267.6|intact:EBI-2860074|uniprotkb:A6ND56|uniprotkb:B7ZLN5|uniprotkb:E7EX85|uniprotkb:Q17RB6	psi-mi:q5nec8_fratt(display_long)|uniprotkb:pdpC2(gene name)|psi-mi:pdpC2(display_short)|uniprotkb:pdpC1(gene name synonym)|uniprotkb:FTT_1354(locus name)|uniprotkb:FTT_1709(locus name)	psi-mi:brpf3_human(display_long)|uniprotkb:BRPF3(gene name)|psi-mi:BRPF3(display_short)|uniprotkb:KIAA1286(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808518|imex:IM-13779-1265	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_170306.1|refseq:YP_170614.1|refseq:WP_003022143.1	"refseq:XP_011512791.1|refseq:XP_005249067.1|refseq:XP_005249068.1|refseq:NP_056510.2|ensembl:ENSG00000096070.19(gene)|ensembl:ENST00000357641.10(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046872""(metal ion binding)|go:""GO:0050793""(regulation of developmental process)|go:""GO:0070776""(MOZ/MORF histone acetyltransferase complex)|go:""GO:1903706""(regulation of hemopoiesis)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR042005|interpro:IPR050701|mint:Q9ULD4|rcsb pdb:3PFS|reactome:R-HSA-114608|reactome:R-HSA-3214847|reactome:R-HSA-6804758|panther:PTHR13793(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tla0QxqaAz50ceSU0349Jpnz3Ng177416	rogid:CgyLb1z0upVoKfJxtzvybQ6NAkE9606	intact-crc:612D98E392D8692A|rigid:F5oprSYOpm8jzE73CdFB2l1p6KU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NWR8	uniprotkb:Q5NE99	intact:EBI-719989|uniprotkb:Q6IAC1|uniprotkb:A8K4Y3|ensembl:ENSP00000378145.4	intact:EBI-2796415	psi-mi:mcub_human(display_long)|uniprotkb:MCUB(gene name)|psi-mi:MCUB(display_short)|uniprotkb:CCDC109B(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 109B(gene name synonym)	psi-mi:secb2_fratt(display_long)|uniprotkb:FTT_1749(locus name)|uniprotkb:secB2(gene name)|psi-mi:secB2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808484|imex:IM-13779-1261	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060388.2|ensembl:ENSG00000005059.16(gene)|ensembl:ENST00000394650.7(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006851""(mitochondrial calcium ion transmembrane transport)|go:""GO:0016020""(membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0034704""(calcium channel complex)|go:""GO:0036444""(calcium import into the mitochondrion)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:0110099""(negative regulation of calcium import into the mitochondrion)|go:""GO:1902726""(positive regulation of skeletal muscle satellite cell differentiation)|go:""GO:1990246""(uniplex complex)|interpro:IPR006769(Protein of unknown function DUF607)|interpro:IPR039055|reactome:R-HSA-8949215|reactome:R-HSA-8949664|panther:PTHR13462(orthology-group)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0006457""(protein folding)|go:""GO:0015031""(protein transport)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051262""(protein tetramerization)|interpro:IPR003708(Bacterial protein export chaperone SecB)|refseq:YP_170643.1|refseq:WP_003013731.1|interpro:IPR035958"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:768P7z3oh77JydfkNLnvlVcSqhY9606	rogid:/Ln+Ppl3hIcqmxWI4W9Mf0EKLFw177416	intact-crc:8615F106B2E7C81E|rigid:1rtD0D7nQajNGpobdG+4RecaiL8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGX7	uniprotkb:A0JLQ5	intact:EBI-2801615	intact:EBI-2808494	psi-mi:pnp_fratt(display_long)|uniprotkb:Polynucleotide phosphorylase(gene name synonym)|uniprotkb:FTT_0699(locus name)|uniprotkb:pnp(gene name)|psi-mi:pnp(display_short)	psi-mi:a0jlq5_human(display_long)|uniprotkb:BXDC2(gene name)|psi-mi:BXDC2(display_short)|uniprotkb:Brix domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808491|imex:IM-13779-1264	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169715.1|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR020568|interpro:IPR027408|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004654""(polyribonucleotide nucleotidyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0006402""(mRNA catabolic process)|refseq:WP_003020501.1|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612"	"interpro:IPR007109(Brix)|interpro:IPR026532|go:""GO:0005730""(nucleolus)|go:""GO:0006364""(rRNA processing)|go:""GO:0019843""(rRNA binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0NGzY8LkmfRcwKNJb6ydU4X1Qxs177416	rogid:7xJqpB4NLExhUla+zFPC+0XkcCg9606	intact-crc:490308209A70C05C|rigid:iVPT+ornEPEm+HnzGaCUIunIK30	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14692	uniprotkb:Q5NEC0	intact:EBI-2513630|uniprotkb:Q86XJ9|uniprotkb:Q5QPT5|ensembl:ENSP00000363642.4	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:bms1_human(display_long)|uniprotkb:BMS1(gene name)|psi-mi:BMS1(display_short)|uniprotkb:BMS1L(gene name synonym)|uniprotkb:KIAA0187(gene name synonym)|uniprotkb:Ribosome assembly protein BMS1 homolog(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808532|imex:IM-13779-1268	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165733.8(gene)|ensembl:ENST00000374518.6(transcript)|go:""GO:0000462""(""maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0000479""(""endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0003723""(RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0032040""(small-subunit processome)|go:""GO:0034511""(U3 snoRNA binding)|go:""GO:0042274""(ribosomal small subunit biogenesis)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR027417|interpro:IPR030387|interpro:IPR037875|interpro:IPR039761|mint:Q14692|rcsb pdb:7MQ9|rcsb pdb:7MQA|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_055568.3|refseq:XP_005271903.1|refseq:XP_011538704.1|efo:""Orphanet:1114""|panther:PTHR12858(orthology-group)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9sd7sK6/Ue4DgLRT+j9Iw0+8om09606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:83E3C2152790C9FF|rigid:2hUbSJ7cX1tLFMGR3jG3Az6h2AA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGX7	uniprotkb:Q13490	intact:EBI-2801615	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758.2|ensembl:ENSP00000477613.1	psi-mi:pnp_fratt(display_long)|uniprotkb:Polynucleotide phosphorylase(gene name synonym)|uniprotkb:FTT_0699(locus name)|uniprotkb:pnp(gene name)|psi-mi:pnp(display_short)	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808539|imex:IM-13779-1266	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169715.1|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR020568|interpro:IPR027408|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004654""(polyribonucleotide nucleotidyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0006402""(mRNA catabolic process)|refseq:WP_003020501.1|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612"	"refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|ensembl:ENSG00000110330.10(gene)|ensembl:ENST00000227758.7(transcript)|ensembl:ENST00000613397.4(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001741""(XY body)|go:""GO:0001890""(placenta development)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016740""(transferase activity)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034121""(regulation of toll-like receptor signaling pathway)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0039535""(regulation of RIG-I signaling pathway)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045088""(regulation of innate immune response)|go:""GO:0045471""(response to ethanol)|go:""GO:0045595""(regulation of cell differentiation)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051591""(response to cAMP)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060544""(regulation of necroptotic process)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070266""(necroptotic process)|go:""GO:0070424""(regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:""GO:0098770""(FBXO family protein binding)|go:""GO:1901222""(regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902443""(negative regulation of ripoptosome assembly involved in necroptotic process)|go:""GO:1902523""(positive regulation of protein K63-linked ubiquitination)|go:""GO:1902524""(positive regulation of protein K48-linked ubiquitination)|go:""GO:1902527""(positive regulation of protein monoubiquitination)|go:""GO:2000116""(obsolete regulation of cysteine-type endopeptidase activity)|go:""GO:2000377""(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|interpro:IPR048875|interpro:IPR050784|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|rcsb pdb:7QGJ|rcsb pdb:7TRL|rcsb pdb:7TRM|rcsb pdb:8DSF|rcsb pdb:8DSO|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|panther:PTHR10044(orthology-group)|dip:DIP-33485N|ensembl:ENSP00000227758.2|ensembl:ENST00000530675.5|ensembl:ENSP00000431723.1|ensembl:ENSP00000477613.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0NGzY8LkmfRcwKNJb6ydU4X1Qxs177416	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	intact-crc:CC3A9D46ACBC9C3E|rigid:INU18XmiDlinqjechOSdnsWnJcA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF37	uniprotkb:Q6W2J9	intact:EBI-2798724	intact:EBI-950027|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4|ensembl:ENSP00000367705.4|ensembl:ENSP00000384485.3|ensembl:ENSP00000483217.2|ensembl:ENSP00000499892.2|ensembl:ENSP00000505507.1|ensembl:ENSP00000505761.1	psi-mi:syp_fratt(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1412(locus name)	psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808553|imex:IM-13779-1267	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044140|refseq:YP_170355.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|interpro:IPR033730|refseq:WP_003022224.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR045864|interpro:IPR050062"	"dip:DIP-50009N|efo:""Orphanet:2712""|efo:""Orphanet:457246""|efo:""Orphanet:520""|efo:""Orphanet:568""|ensembl:ENSG00000183337.18(gene)|ensembl:ENST00000378444.9(transcript)|ensembl:ENST00000406200.4(transcript)|ensembl:ENST00000615339.2(transcript)|ensembl:ENST00000672922.2(transcript)|ensembl:ENST00000679513.1(transcript)|ensembl:ENST00000680831.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001835""(blastocyst hatching)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0007507""(heart development)|go:""GO:0030502""(negative regulation of bone mineralization)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042476""(odontogenesis)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060021""(roof of mouth development)|go:""GO:0065001""(specification of axis polarity)|go:""GO:0070171""(negative regulation of tooth mineralization)|go:""GO:0140261""(BCOR complex)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR002110(Ankyrin)|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|interpro:IPR047144|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|rcsb pdb:8HCU|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_016885104.1|panther:PTHR24117(orthology-group)|ensembl:ENST00000342274.8|ensembl:ENSP00000345923.4|ensembl:ENSP00000367705.4|ensembl:ENST00000378455.8|ensembl:ENSP00000367716.4|ensembl:ENST00000397354.7|ensembl:ENSP00000380512.3|ensembl:ENSP00000384485.3|ensembl:ENSP00000483217.2|ensembl:ENSP00000499892.2|ensembl:ENST00000673391.1|ensembl:ENSP00000500446.1|ensembl:ENSP00000505761.1|ensembl:ENSP00000505507.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6/QkU5JRWJEBZMwaR9J83no0ffk177416	rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606	intact-crc:F528911724C574A3|rigid:QJgch6HzOMcCJ2PP/+8z5R5Tc2A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIJ1	uniprotkb:Q9NZS9	intact:EBI-2801762	intact:EBI-2130199|ensembl:ENSP00000261658.2|ensembl:ENSP00000478190.1|uniprotkb:A8K4Z9|uniprotkb:D3DUG8|uniprotkb:B4DUT0	psi-mi:q5nij1_fratt(display_long)|uniprotkb:sucA(gene name)|psi-mi:sucA(display_short)|uniprotkb:FTT_0076(locus name)	psi-mi:bfar_human(display_long)|uniprotkb:BFAR(gene name)|psi-mi:BFAR(display_short)|uniprotkb:BAR(gene name synonym)|uniprotkb:RNF47(gene name synonym)|uniprotkb:RING finger protein 47(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808546|imex:IM-13779-1269	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031717|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|refseq:YP_169151.1|go:""GO:0004591""(""oxoglutarate dehydrogenase (succinyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|interpro:IPR029061|interpro:IPR042179"	"ensembl:ENSG00000103429.11(gene)|ensembl:ENSG00000275618.2(gene)|ensembl:ENST00000261658.7(transcript)|ensembl:ENST00000619034.2(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0089720""(caspase binding)|go:""GO:1903895""(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017907|refseq:NP_057645.1|refseq:XP_005255407.1|panther:PTHR15898(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dQc/mmfwgUYZL0zzhIJG4HqrrDA177416	rogid:XDPFsRmdbch1NXffLOcE0lVrtRo9606	intact-crc:828635E926B33D46|rigid:vTZrFI9IotkxLS21jslxuU1eMKQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46379	uniprotkb:Q5NET1	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2799872|uniprotkb:A0A0G2RMN9	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:q5net1_fratt(display_long)|uniprotkb:fadA(gene name)|psi-mi:fadA(display_short)|uniprotkb:FTT_1531(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808577|imex:IM-13779-1273	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020615|interpro:IPR020610|interpro:IPR020617|interpro:IPR020613|interpro:IPR020616|refseq:YP_170461.1|go:""GO:0003988""(acetyl-CoA C-acyltransferase activity)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0010124""(phenylacetate catabolic process)|refseq:WP_003014953.1|interpro:IPR050215"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:G7eXVKsS/V6cDu1kiIN/rXBheXs177416	intact-crc:199F31E90634DBA7|rigid:xJzKBQ/6alp3LNlLR4MAVruh/ms	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46379	uniprotkb:Q5NEP4	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2802121|uniprotkb:A0A0G2RNJ4	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:q5nep4_fratt(display_long)|uniprotkb:FTT_1576(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808584|imex:IM-13779-1271	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"refseq:YP_170498.1|refseq:WP_003022484.1|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:qivaxTncNwJ4rDFodbXHR2exiRI177416	intact-crc:695B31E9071AAAC6|rigid:Zm3zP7Nh4zIZde26Jb8ZUCtkBQU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI22	uniprotkb:P46379	intact:EBI-2800722	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:q5ni22_fratt(display_long)|uniprotkb:FTT_0268(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808570|imex:IM-13779-1270	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006153(Sodium/hydrogen exchanger)|refseq:YP_169320.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015297""(antiporter activity)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR038770|refseq:WP_003021716.1|interpro:IPR036291"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8gIkzC54dMaRbxYAhkGbRFLBfHU177416	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:BC677DE906C72C65|rigid:6/XqLxCCI7329s0j8Ufvza1jvgI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46379	uniprotkb:Q5NIQ2	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2808560|uniprotkb:A0A0G2RQA1	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:q5niq2_fratt(display_long)|uniprotkb:FTT_0014c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808563|imex:IM-13779-1272	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	refseq:YP_169090.1|refseq:WP_003022843.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:ISlioVbjHlyAfP1mMZJiq47pJE4177416	intact-crc:17B47DE906D0F6BA|rigid:Dy3O4ZyvG7+yvYUCnbdjoL0g+Bc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q5NGK2	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2808601	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:q5ngk2_fratt(display_long)|uniprotkb:FTT_0835(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808604|imex:IM-13779-1274	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|refseq:YP_169840.1|interpro:IPR043130|go:""GO:0003882""(CDP-diacylglycerol-serine O-phosphatidyltransferase activity)|go:""GO:0008654""(phospholipid biosynthetic process)|go:""GO:0016020""(membrane)|refseq:WP_003020795.1|interpro:IPR048254"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:G9weDP5n97MYjxvJRL6Q15/k+/o177416	intact-crc:25052E2276FC66DB|rigid:Z1/Z4ke9cNREBQRLgGqCJRLnHQQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIE8	uniprotkb:Q99933	intact:EBI-2808594|uniprotkb:A0A0G2RNT6	intact:EBI-1030678|uniprotkb:O75315|uniprotkb:Q14414|uniprotkb:Q96TG2|uniprotkb:Q9Y2V4|uniprotkb:Q53H32|uniprotkb:Q5VZE8|uniprotkb:Q5VZE9|uniprotkb:Q5VZF0|ensembl:ENSP00000489189.2	psi-mi:q5nie8_fratt(display_long)|uniprotkb:FTT_0127c(locus name)	psi-mi:bag1_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:Bcl-2-associated athanogene 1(gene name synonym)|uniprotkb:HAP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808591|imex:IM-13779-1276	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|refseq:YP_169194.1|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR050189|refseq:WP_003019882.1|interpro:IPR036259"	"refseq:NP_001165886.1|refseq:NP_004314.5|dip:DIP-3341N|ensembl:ENSG00000107262.26(gene)|ensembl:ENST00000634734.3(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034393""(positive regulation of smooth muscle cell apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0050821""(protein stabilization)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR029071|interpro:IPR036533|interpro:IPR039773|mint:Q99933|rcsb pdb:1HX1|rcsb pdb:1WXV|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|reactome:R-HSA-3371453|panther:PTHR12329(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Odhj5epy5w1FkzGfraULJPzNCLY177416	rogid:wDyAGECTy45td5tL4mnwa1txPO49606	intact-crc:056F4F83EC794819|rigid:sfhU41y18OX1xFT0YjZb3lnV1Pk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q5NFV6	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2797055|uniprotkb:A0A0G2RM43	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:q5nfv6_fratt(display_long)|uniprotkb:rpoH(gene name)|psi-mi:rpoH(display_short)|uniprotkb:RNA polymerase sigma-32 factor(gene name synonym)|uniprotkb:FTT_1112c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808611|imex:IM-13779-1277	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0009408""(response to heat)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0016987""(sigma factor activity)|refseq:YP_170086.1|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012759(RNA polymerase sigma factor RpoH, proteobacteria)|refseq:WP_003021274.1|interpro:IPR050813"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:TUiRpVCoti/MNhIPmxh1x7nUv4Q177416	intact-crc:B5F55F2277899C6C|rigid:OfCLOkFVi2QqCg8Wxog6SVLN0z8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NET3	uniprotkb:P61769	intact:EBI-2801773	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	psi-mi:q5net3_fratt(display_long)|uniprotkb:fadE(gene name)|psi-mi:fadE(display_short)|uniprotkb:FTT_1529(locus name)	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808618|imex:IM-13779-1275	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR015396(Protein of unknown function DUF1974)|refseq:YP_170459.3|go:""GO:0004466""(long-chain fatty acyl-CoA dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0033539""(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070991""(medium-chain fatty acyl-CoA dehydrogenase activity)|interpro:IPR036250|interpro:IPR037069|interpro:IPR050741|interpro:IPR046373"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:kKeqoKaBPWvIJmVTDMU1BWCVmTc177416	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	intact-crc:DB70CC2276A627EB|rigid:XBUP6ab4LJm4T9/URc9RQQT0ULU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHL4	uniprotkb:Q9UPN4	intact:EBI-2804916|uniprotkb:A0A0G2RNY8	intact:EBI-2558372|uniprotkb:B2RN11|uniprotkb:Q96F50|uniprotkb:A6NHI8|ensembl:ENSP00000269392.4	"psi-mi:q5nhl4_fratt(display_long)|uniprotkb:mpl(gene name)|psi-mi:mpl(display_short)|uniprotkb:Murein peptide ligase(gene name synonym)|uniprotkb:""UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase""(gene name synonym)|uniprotkb:FTT_0438(locus name)"	psi-mi:cp131_human(display_long)|uniprotkb:CEP131(gene name)|psi-mi:CEP131(display_short)|uniprotkb:5-azacytidine-induced protein 1(gene name synonym)|uniprotkb:AZI1(gene name synonym)|uniprotkb:KIAA1118(gene name synonym)|uniprotkb:Pre-acrosome localization protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808635|imex:IM-13779-1278	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005757(""UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase"")|refseq:YP_169478.1|go:""GO:0005524""(ATP binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0009254""(peptidoglycan turnover)|go:""GO:0051301""(cell division)|go:""GO:0071555""(cell wall organization)|go:""GO:0106418""(UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase activity)|refseq:WP_003020193.1|interpro:IPR036565|interpro:IPR036615|interpro:IPR050061"	"refseq:NP_001009811.2|refseq:NP_055799.2|refseq:NP_001306157.1|dip:DIP-56658N|ensembl:ENSG00000141577.14(gene)|ensembl:ENST00000269392.8(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0002177""(manchette)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0007288""(sperm axoneme assembly)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035735""(intraciliary transport involved in cilium assembly)|go:""GO:0035869""(ciliary transition zone)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0060271""(cilium assembly)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0120212""(sperm head-tail coupling apparatus)|go:""GO:1905198""(manchette assembly)|go:""GO:1905515""(non-motile cilium assembly)|go:""GO:1990953""(intramanchette transport)|interpro:IPR030465|mint:Q9UPN4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|panther:PTHR31540(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/26	rogid:6uME0/eIBas6qdPU6ajdbqJXUsY177416	rogid:qcnzG6vfogSEappaH9nv7P3kSoQ9606	intact-crc:FDC80B74EF37C0E7|rigid:45ZNNr8oijvDhd6RMwt1HiNPh8g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q5NEN2	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2808628|uniprotkb:A0A0G2RND2	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:q5nen2_fratt(display_long)|uniprotkb:FTT_1594(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808625|imex:IM-13779-1280	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|refseq:YP_170510.1|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005829""(cytosol)|interpro:IPR050950|refseq:WP_003022513.1|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:SrxfFMixBQLkxZk6kUIDBis+EMc177416	intact-crc:7C0ACC2276FD4960|rigid:OjEsK7EjE0umu2xFd08x8eyQHhU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI90	uniprotkb:O15169	intact:EBI-2796997|uniprotkb:A0A0G2RNC0	intact:EBI-710484|ensembl:ENSP00000262320.3|uniprotkb:Q4TT26|uniprotkb:Q4TT27|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:q5ni90_fratt(display_long)|uniprotkb:prfB(gene name)|psi-mi:prfB(display_short)|uniprotkb:FTT_0191(locus name)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808642|imex:IM-13779-1281	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004374(Peptide chain release factor 2)|refseq:YP_169252.1|go:""GO:0005737""(cytoplasm)|go:""GO:0016149""(translation release factor activity, codon specific)|interpro:IPR045853"	"ensembl:ENSG00000103126.15(gene)|ensembl:ENST00000262320.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002039""(p53 binding)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009950""(dorsal/ventral axis specification)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030877""(beta-catenin destruction complex)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032147""(activation of protein kinase activity)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044725""(epigenetic programming in the zygotic pronuclei)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046332""(SMAD binding)|go:""GO:0048320""(axial mesoderm formation)|go:""GO:0048468""(cell development)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060322""(head development)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070411""(I-SMAD binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0071944""(cell periphery)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:1904885""(beta-catenin destruction complex assembly)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:1990909""(Wnt signalosome)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|interpro:IPR044926|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|rcsb pdb:7SXF|rcsb pdb:7SXG|rcsb pdb:7SXH|rcsb pdb:7SXJ|rcsb pdb:7Y1P|rcsb pdb:8RU3|rcsb pdb:8RU4|rcsb pdb:8VMG|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|refseq:NP_003493.1|refseq:NP_851393.1|efo:""Orphanet:210159""|dip:DIP-34630N|panther:PTHR46102(orthology-group)|ensembl:ENSP00000262320.3|ensembl:ENST00000354866.7|ensembl:ENSP00000346935.3"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:xfYbStHp/nzMNqFfoH4i6+wOWBI177416	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	intact-crc:B0C759E801607F74|rigid:alGs6xj2njNXo/0S9vYe1FyQSC4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF52	uniprotkb:O15169	intact:EBI-2801584|uniprotkb:A0A0G2RNY6	intact:EBI-710484|ensembl:ENSP00000262320.3|uniprotkb:Q4TT26|uniprotkb:Q4TT27|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:q5nf52_fratt(display_long)|uniprotkb:FTT_1395c(locus name)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808649|imex:IM-13779-1279	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007421(ATPase associated with various cellular activities, AAA-4)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:YP_170340.1|interpro:IPR025831|go:""GO:0004386""(helicase activity)|refseq:WP_003022198.1|interpro:IPR038461|interpro:IPR038475|interpro:IPR036388|interpro:IPR036390"	"ensembl:ENSG00000103126.15(gene)|ensembl:ENST00000262320.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002039""(p53 binding)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009950""(dorsal/ventral axis specification)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030877""(beta-catenin destruction complex)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032147""(activation of protein kinase activity)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044725""(epigenetic programming in the zygotic pronuclei)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046332""(SMAD binding)|go:""GO:0048320""(axial mesoderm formation)|go:""GO:0048468""(cell development)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060322""(head development)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070411""(I-SMAD binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0071944""(cell periphery)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:1904885""(beta-catenin destruction complex assembly)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:1990909""(Wnt signalosome)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|interpro:IPR044926|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|rcsb pdb:7SXF|rcsb pdb:7SXG|rcsb pdb:7SXH|rcsb pdb:7SXJ|rcsb pdb:7Y1P|rcsb pdb:8RU3|rcsb pdb:8RU4|rcsb pdb:8VMG|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|refseq:NP_003493.1|refseq:NP_851393.1|efo:""Orphanet:210159""|dip:DIP-34630N|panther:PTHR46102(orthology-group)|ensembl:ENSP00000262320.3|ensembl:ENST00000354866.7|ensembl:ENSP00000346935.3"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:jXG9mH+7eRZFsFBHYoB3CjJacm0177416	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	intact-crc:087286E801DA16F1|rigid:P1Av2fyvowv2MtU81xNx9jLmeBM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UNA0	uniprotkb:Q5NI35	intact:EBI-2808663|uniprotkb:Q9UKP2|uniprotkb:Q52LV4|ensembl:ENSP00000284987.5	intact:EBI-2806239|uniprotkb:A0A0G2RM01	psi-mi:ats5_human(display_long)|uniprotkb:ADAMTS5(gene name)|psi-mi:ADAMTS5(display_short)|uniprotkb:ADAMTS11(gene name synonym)|uniprotkb:ADMP2(gene name synonym)|uniprotkb:A disintegrin and metalloproteinase with thrombospondin motifs 11(gene name synonym)|uniprotkb:ADMP-2(gene name synonym)|uniprotkb:Aggrecanase-2(gene name synonym)	psi-mi:q5ni35_fratt(display_long)|uniprotkb:FTT_0255c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808669|imex:IM-13779-1282	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_008969.2|ensembl:ENSG00000154736.6(gene)|ensembl:ENST00000284987.6(transcript)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006508""(proteolysis)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008201""(heparin binding)|go:""GO:0008233""(peptidase activity)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0031012""(extracellular matrix)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR013273(Peptidase M12B, ADAM-TS)|interpro:IPR013276(Peptidase M12B, ADAM-TS5)|interpro:IPR024079|interpro:IPR036383|interpro:IPR041645|interpro:IPR045371|interpro:IPR050439|rcsb pdb:2RJQ|rcsb pdb:3B8Z|rcsb pdb:3HY7|rcsb pdb:3HY9|rcsb pdb:3HYG|rcsb pdb:3LJT|rcsb pdb:6YJM|reactome:R-HSA-1474228|reactome:R-HSA-5083635|reactome:R-HSA-5173214|panther:PTHR13723(orthology-group)"	refseq:WP_003021741.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:J+ZTdYjh2OrzLQM4ZUXxbyKaPHo9606	rogid:F3RJgLgthy18D0NNHEg8O1eMGBY177416	intact-crc:D486D47D95EBC3FB|rigid:LsaBrNf6uMIEkD4LoR02k093/zA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13315	uniprotkb:Q5NF53	intact:EBI-495465|uniprotkb:O15429|uniprotkb:Q12758|uniprotkb:Q16551|uniprotkb:Q93007|uniprotkb:Q9NP02|uniprotkb:Q9UCX7|intact:EBI-1059333|uniprotkb:B2RNX5|ensembl:ENSP00000278616.4|ensembl:ENSP00000388058.2|ensembl:ENSP00000469471.2|ensembl:ENSP00000501606.1|ensembl:ENSP00000519149.1|intact:EBI-28985245	intact:EBI-2797592|uniprotkb:A0A0G2RMJ2	psi-mi:atm_human(display_long)|uniprotkb:ATM(gene name)|psi-mi:ATM(display_short)|uniprotkb:Ataxia telangiectasia mutated(gene name synonym)	psi-mi:q5nf53_fratt(display_long)|uniprotkb:recB(gene name)|psi-mi:recB(display_short)|uniprotkb:Exonuclease V subunit RecB(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecB(gene name synonym)|uniprotkb:FTT_1394c(locus name)|uniprotkb:DNA 3'-5' helicase subunit RecB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808683|imex:IM-13779-1283	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:440437""|efo:""Orphanet:100""|efo:""Orphanet:1331""|efo:""Orphanet:370109""|efo:""Orphanet:52416""|efo:""Orphanet:67038""|ensembl:ENSG00000149311.22(gene)|ensembl:ENST00000278616.10(transcript)|ensembl:ENST00000452508.7(transcript)|ensembl:ENST00000601453.3(transcript)|ensembl:ENST00000675843.1(transcript)|ensembl:ENST00000713844.1(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000425""(pexophagy)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000729""(DNA double-strand break processing)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001756""(somitogenesis)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006974""(DNA damage response)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007131""(reciprocal meiotic recombination)|go:""GO:0007140""(male meiotic nuclear division)|go:""GO:0007143""(female meiotic nuclear division)|go:""GO:0007165""(signal transduction)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010212""(response to ionizing radiation)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016303""(1-phosphatidylinositol-3-kinase activity)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0032210""(regulation of telomere maintenance via telomerase)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0033151""(""V(D)J recombination"")|go:""GO:0033554""(cellular response to stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035861""(site of double-strand break)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0042159""(lipoprotein catabolic process)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043517""(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045141""(meiotic telomere clustering)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048538""(thymus development)|go:""GO:0048599""(oocyte development)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0071500""(cellular response to nitrosative stress)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090398""(cellular senescence)|go:""GO:0090399""(replicative senescence)|go:""GO:0097694""(establishment of RNA localization to telomere)|go:""GO:0097695""(establishment of protein-containing complex localization to telomere)|go:""GO:0098850""(extrinsic component of synaptic vesicle membrane)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1903626""(positive regulation of DNA catabolic process)|go:""GO:1903978""(regulation of microglial cell activation)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904354""(negative regulation of telomere capping)|go:""GO:1904358""(positive regulation of telomere maintenance via telomere lengthening)|go:""GO:1904884""(positive regulation of telomerase catalytic core complex assembly)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990391""(DNA repair complex)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021668|interpro:IPR036940|interpro:IPR038980|interpro:IPR044107|mint:Q13315|rcsb pdb:5NP0|rcsb pdb:5NP1|rcsb pdb:6HKA|rcsb pdb:6K9K|rcsb pdb:6K9L|rcsb pdb:7NI4|rcsb pdb:7NI5|rcsb pdb:7NI6|rcsb pdb:7SIC|rcsb pdb:7SID|rcsb pdb:8OXM|rcsb pdb:8OXO|rcsb pdb:8OXP|rcsb pdb:8OXQ|reactome:R-HSA-2559586|reactome:R-HSA-3371453|reactome:R-HSA-349425|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803207|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69473|reactome:R-HSA-69541|reactome:R-HSA-912446|reactome:R-HSA-9664873|reactome:R-HSA-9701192|reactome:R-HSA-9704331|reactome:R-HSA-9704646|reactome:R-HSA-9709570|reactome:R-HSA-9709603|refseq:NP_000042.3|refseq:XP_005271618.2|refseq:XP_005271619.2|refseq:XP_006718906.1|refseq:XP_006718908.1|refseq:XP_011541142.1|refseq:XP_016873278.1|refseq:XP_016873279.1|dip:DIP-182N|efo:""Orphanet:227535""|panther:PTHR11139(orthology-group)|ensembl:ENSP00000278616.4|ensembl:ENSP00000388058.2|ensembl:ENSP00000469471.2|ensembl:ENSP00000501606.1|ensembl:ENSP00000519149.1"	"go:""GO:0000287""(magnesium ion binding)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR004586(Exodeoxyribonuclease V, beta subunit)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|refseq:YP_170339.1|interpro:IPR027417|refseq:WP_003022196.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:d/FYo7KdBblfR/inXUZpFlWTfoo9606	rogid:ii9dJldcaJ9ed2JkD66pMgtmBlQ177416	intact-crc:06106B7C012ECDDD|rigid:B0g8uSnGegFenDf6RVFmqAag1wQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV3	uniprotkb:Q13315	intact:EBI-2797317	intact:EBI-495465|uniprotkb:O15429|uniprotkb:Q12758|uniprotkb:Q16551|uniprotkb:Q93007|uniprotkb:Q9NP02|uniprotkb:Q9UCX7|intact:EBI-1059333|uniprotkb:B2RNX5|ensembl:ENSP00000278616.4|ensembl:ENSP00000388058.2|ensembl:ENSP00000469471.2|ensembl:ENSP00000501606.1|ensembl:ENSP00000519149.1|intact:EBI-28985245	psi-mi:q5ngv3_fratt(display_long)|uniprotkb:FTT_0726c(locus name)	psi-mi:atm_human(display_long)|uniprotkb:ATM(gene name)|psi-mi:ATM(display_short)|uniprotkb:Ataxia telangiectasia mutated(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808676|imex:IM-13779-1285	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0006629""(lipid metabolic process)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|interpro:IPR017946|refseq:YP_169739.1|interpro:IPR030395|refseq:WP_003020543.1"	"efo:""Orphanet:440437""|efo:""Orphanet:100""|efo:""Orphanet:1331""|efo:""Orphanet:370109""|efo:""Orphanet:52416""|efo:""Orphanet:67038""|ensembl:ENSG00000149311.22(gene)|ensembl:ENST00000278616.10(transcript)|ensembl:ENST00000452508.7(transcript)|ensembl:ENST00000601453.3(transcript)|ensembl:ENST00000675843.1(transcript)|ensembl:ENST00000713844.1(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000425""(pexophagy)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000729""(DNA double-strand break processing)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001756""(somitogenesis)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006974""(DNA damage response)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007131""(reciprocal meiotic recombination)|go:""GO:0007140""(male meiotic nuclear division)|go:""GO:0007143""(female meiotic nuclear division)|go:""GO:0007165""(signal transduction)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010212""(response to ionizing radiation)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016303""(1-phosphatidylinositol-3-kinase activity)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0032210""(regulation of telomere maintenance via telomerase)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0033151""(""V(D)J recombination"")|go:""GO:0033554""(cellular response to stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035861""(site of double-strand break)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0042159""(lipoprotein catabolic process)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043517""(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045141""(meiotic telomere clustering)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048538""(thymus development)|go:""GO:0048599""(oocyte development)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0071500""(cellular response to nitrosative stress)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090398""(cellular senescence)|go:""GO:0090399""(replicative senescence)|go:""GO:0097694""(establishment of RNA localization to telomere)|go:""GO:0097695""(establishment of protein-containing complex localization to telomere)|go:""GO:0098850""(extrinsic component of synaptic vesicle membrane)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1903626""(positive regulation of DNA catabolic process)|go:""GO:1903978""(regulation of microglial cell activation)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904354""(negative regulation of telomere capping)|go:""GO:1904358""(positive regulation of telomere maintenance via telomere lengthening)|go:""GO:1904884""(positive regulation of telomerase catalytic core complex assembly)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990391""(DNA repair complex)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021668|interpro:IPR036940|interpro:IPR038980|interpro:IPR044107|mint:Q13315|rcsb pdb:5NP0|rcsb pdb:5NP1|rcsb pdb:6HKA|rcsb pdb:6K9K|rcsb pdb:6K9L|rcsb pdb:7NI4|rcsb pdb:7NI5|rcsb pdb:7NI6|rcsb pdb:7SIC|rcsb pdb:7SID|rcsb pdb:8OXM|rcsb pdb:8OXO|rcsb pdb:8OXP|rcsb pdb:8OXQ|reactome:R-HSA-2559586|reactome:R-HSA-3371453|reactome:R-HSA-349425|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803207|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69473|reactome:R-HSA-69541|reactome:R-HSA-912446|reactome:R-HSA-9664873|reactome:R-HSA-9701192|reactome:R-HSA-9704331|reactome:R-HSA-9704646|reactome:R-HSA-9709570|reactome:R-HSA-9709603|refseq:NP_000042.3|refseq:XP_005271618.2|refseq:XP_005271619.2|refseq:XP_006718906.1|refseq:XP_006718908.1|refseq:XP_011541142.1|refseq:XP_016873278.1|refseq:XP_016873279.1|dip:DIP-182N|efo:""Orphanet:227535""|panther:PTHR11139(orthology-group)|ensembl:ENSP00000278616.4|ensembl:ENSP00000388058.2|ensembl:ENSP00000469471.2|ensembl:ENSP00000501606.1|ensembl:ENSP00000519149.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:3e+5yrpF/Mx2IYeXH2egqOFVYbs177416	rogid:d/FYo7KdBblfR/inXUZpFlWTfoo9606	intact-crc:3D1E1A7C0139175E|rigid:wYEPRuzU/v5Zg9SIfjzgQVt6t/4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHZ4	uniprotkb:P54253	intact:EBI-2798091	intact:EBI-930964|uniprotkb:Q17S02|ensembl:ENSP00000244769.3|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|ensembl:ENSP00000416360.1	psi-mi:syv_fratt(display_long)|uniprotkb:valS(gene name)|psi-mi:valS(display_short)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0299(locus name)	psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808656|imex:IM-13779-1284	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004832""(valine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006438""(valyl-tRNA aminoacylation)|refseq:YP_169348.1|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR019499|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR033705|refseq:WP_003021639.1|interpro:IPR037118"	"ensembl:ENSG00000124788.19(gene)|ensembl:ENST00000244769.8(transcript)|ensembl:ENST00000436367.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0007420""(brain development)|go:""GO:0007612""(learning)|go:""GO:0007613""(memory)|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0016363""(nuclear matrix)|go:""GO:0034046""(""poly(G) binding"")|go:""GO:0035176""(social behavior)|go:""GO:0042405""(nuclear inclusion body)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051168""(nuclear export)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR020997|interpro:IPR036096|interpro:IPR043404|mint:P54253|rcsb pdb:1OA8|rcsb pdb:2M41|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6QIU|refseq:NP_000323.2|refseq:NP_001121636.1|dip:DIP-35353N|efo:""Orphanet:98755""|panther:PTHR13392(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/28	rogid:x/UHW8BtUK4O+DP24Ws5NMlvUpw177416	rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606	intact-crc:3A02149C5BA76E0D|rigid:OiFDMDFF3PN1DfRKKoACQkBbKbA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UII2	uniprotkb:Q5NH50	intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203.5|ensembl:ENSP00000494248.1	intact:EBI-2808700	"psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:""Inhibitor of F(1)F(o)-ATPase""(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short)"	psi-mi:kith_fratt(display_long)|uniprotkb:tdk(gene name)|psi-mi:tdk(display_short)|uniprotkb:FTT_0621(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808697|imex:IM-13779-1286	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770.18(gene)|ensembl:ENSG00000285390.2(gene)|ensembl:ENST00000335514.10(transcript)|ensembl:ENST00000647074.2(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0009986""(cell surface)|go:""GO:0019899""(enzyme binding)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042030""(ATPase inhibitor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043532""(angiostatin binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051346""(negative regulation of hydrolase activity)|go:""GO:0051882""(mitochondrial depolarization)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0140260""(mitochondrial proton-transporting ATP synthase complex binding)|go:""GO:1901030""(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1903052""(positive regulation of proteolysis involved in protein catabolic process)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|go:""GO:1903578""(regulation of ATP metabolic process)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1905707""(negative regulation of mitochondrial ATP synthesis coupled proton transport)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|rcsb pdb:8H9E|rcsb pdb:8H9L|rcsb pdb:8H9S|rcsb pdb:8H9U|rcsb pdb:8KI3|panther:PTHR23407(orthology-group)"	"interpro:IPR001267(Thymidine kinase)|refseq:YP_169642.1|interpro:IPR027417|go:""GO:0004797""(thymidine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0046104""(thymidine metabolic process)|go:""GO:0071897""(DNA biosynthetic process)|refseq:WP_003029109.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606	rogid:doKqzHrKe/8s1rhjlQ0q0s2NjoU177416	intact-crc:C476C41D448572B5|rigid:wu2tCZNkF2mLRaPVsc5ZZR/yRIg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGF1	uniprotkb:Q9H1I8	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	intact:EBI-711197|ensembl:ENSP00000305502.3|ensembl:ENSP00000380877.2|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808722|imex:IM-13779-1290	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"ensembl:ENSG00000100325.15(gene)|ensembl:ENST00000307790.8(transcript)|ensembl:ENST00000397771.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006307""(DNA alkylation repair)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016607""(nuclear speck)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0099053""(obsolete activating signal cointegrator 1 complex)|go:""GO:1990116""(ribosome-associated ubiquitin-dependent protein catabolic process)|go:""GO:1990391""(DNA repair complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|interpro:IPR052586|mint:Q9H1I8|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:NP_115580.2|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1|panther:PTHR21494(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606	intact-crc:B418E255D35F33C1|rigid:Sn3W1tr1vO+t9cg2od39XOPWhRE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UII2	uniprotkb:Q5NH37	intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203.5|ensembl:ENSP00000494248.1	intact:EBI-2796219|uniprotkb:A0A0G2RMX6	"psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:""Inhibitor of F(1)F(o)-ATPase""(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short)"	psi-mi:q5nh37_fratt(display_long)|uniprotkb:hflC(gene name)|psi-mi:hflC(display_short)|uniprotkb:FTT_0634(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808690|imex:IM-13779-1288	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770.18(gene)|ensembl:ENSG00000285390.2(gene)|ensembl:ENST00000335514.10(transcript)|ensembl:ENST00000647074.2(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0009986""(cell surface)|go:""GO:0019899""(enzyme binding)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042030""(ATPase inhibitor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043532""(angiostatin binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051346""(negative regulation of hydrolase activity)|go:""GO:0051882""(mitochondrial depolarization)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0140260""(mitochondrial proton-transporting ATP synthase complex binding)|go:""GO:1901030""(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1903052""(positive regulation of proteolysis involved in protein catabolic process)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|go:""GO:1903578""(regulation of ATP metabolic process)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1905707""(negative regulation of mitochondrial ATP synthesis coupled proton transport)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|rcsb pdb:8H9E|rcsb pdb:8H9L|rcsb pdb:8H9S|rcsb pdb:8H9U|rcsb pdb:8KI3|panther:PTHR23407(orthology-group)"	"go:""GO:0016020""(membrane)|interpro:IPR001107(Band 7 protein)|interpro:IPR010200(HflC)|refseq:YP_169655.1|refseq:WP_003018795.1|interpro:IPR036013"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606	rogid:D91nsJMEfSjitv7++sPB1cVKq9M177416	intact-crc:AC50C41D451244D8|rigid:Rp6diPlzJPNYsftzw820IEuXFu0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFN4	uniprotkb:Q96KQ4	intact:EBI-2796796	intact:EBI-1105153|uniprotkb:B2RMX5|uniprotkb:O94870|ensembl:ENSP00000202556.9	psi-mi:uvrb_fratt(display_long)|uniprotkb:Excinuclease ABC subunit B(gene name synonym)|uniprotkb:FTT_1199c(locus name)|uniprotkb:uvrB(gene name)|psi-mi:uvrB(display_short)	psi-mi:aspp1_human(display_long)|uniprotkb:PPP1R13B(gene name)|psi-mi:PPP1R13B(display_short)|uniprotkb:ASPP1(gene name synonym)|uniprotkb:KIAA0771(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 13B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808708|imex:IM-13779-1289	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170158.1|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004807(Excinuclease ABC, B subunit)|interpro:IPR024759|interpro:IPR027417|interpro:IPR036876|interpro:IPR041471|refseq:WP_003021449.1"	"refseq:NP_056131.2|ensembl:ENSG00000088808.18(gene)|ensembl:ENST00000202556.14(transcript)|go:""GO:0002039""(p53 binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR028319|interpro:IPR029071|interpro:IPR036028|interpro:IPR036770|interpro:IPR047163|interpro:IPR048942|mint:Q96KQ4|rcsb pdb:6HL5|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803211|reactome:R-HSA-6804759|panther:PTHR24131(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Jhq9KYkHYrpyhq5qkOrHkcqCWVk177416	rogid:68vrjCXCm2NiwUih4QbAqeT3Jj49606	intact-crc:FC01E3F3E158F349|rigid:4DRs8M1uc3r8hvsINa0A+b7K8ew	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEP4	uniprotkb:Q9UBL3	intact:EBI-2802121|uniprotkb:A0A0G2RNJ4	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|uniprotkb:A8K7C3|uniprotkb:D3DSW9|ensembl:ENSP00000340896.5	psi-mi:q5nep4_fratt(display_long)|uniprotkb:FTT_1576(locus name)	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808715|imex:IM-13779-1287	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_170498.1|refseq:WP_003022484.1|go:""GO:0016020""(membrane)"	"refseq:NP_001098684.1|refseq:NP_004665.2|refseq:NP_001248761.1|ensembl:ENSG00000129691.16(gene)|ensembl:ENST00000343823.11(transcript)|go:""GO:0000791""(euchromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006974""(DNA damage response)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0030097""(hemopoiesis)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0043627""(response to estrogen)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0071339""(MLL1 complex)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|interpro:IPR043136|interpro:IPR049455|interpro:IPR053835|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|rcsb pdb:7MBM|rcsb pdb:7MBN|rcsb pdb:7UD5|rcsb pdb:7W67|rcsb pdb:7W6A|rcsb pdb:7W6I|rcsb pdb:7W6J|rcsb pdb:7W6L|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922|dip:DIP-29222N|panther:PTHR10598(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:qivaxTncNwJ4rDFodbXHR2exiRI177416	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	intact-crc:43DEABA6BC1EA630|rigid:SVR0nUWYn4iZkYcYguBiz9WzFL4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGW2	uniprotkb:P49407	intact:EBI-2796474|uniprotkb:A0A0G2RND5	intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581.2	psi-mi:q5ngw2_fratt(display_long)|uniprotkb:FTT_0715(locus name)	psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808750|imex:IM-13779-1294	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0004568""(chitinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR029070|refseq:YP_169730.1|interpro:IPR003610(Carbohydrate-binding family V/XII)|interpro:IPR011583(Chitinase II)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_003020524.1|interpro:IPR036116|interpro:IPR036573|interpro:IPR050314"	"refseq:NP_004032.2|refseq:NP_064647.1|dip:DIP-29979N|ensembl:ENSG00000137486.17(gene)|ensembl:ENST00000420843.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002031""(G protein-coupled receptor internalization)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0015031""(protein transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031143""(pseudopodium)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031701""(angiotensin receptor binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:1990763""(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|rcsb pdb:7R0C|rcsb pdb:7R0J|rcsb pdb:7SRS|rcsb pdb:8AS2|rcsb pdb:8AS3|rcsb pdb:8AS4|rcsb pdb:8JRV|rcsb pdb:8WRZ|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9839389|panther:PTHR11792(orthology-group)|ensembl:ENST00000360025.7|ensembl:ENSP00000353124.3|ensembl:ENSP00000409581.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:hPHdF34TD5FCXE5bWyEmg/dd7sg177416	rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606	intact-crc:280B55C9AD115918|rigid:n3vqlYSBozMY8pf3V3LvYJPO2YQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGD0	uniprotkb:P32121	intact:EBI-2798136	intact:EBI-714559|uniprotkb:Q0Z8D3|uniprotkb:Q2PP19|uniprotkb:Q6ICT3|uniprotkb:Q8N7Y2|uniprotkb:Q9UEQ6|uniprotkb:B7WPL3|uniprotkb:B5B0C0|uniprotkb:D3DTK2|intact:EBI-28974065|uniprotkb:B4DLW0|uniprotkb:H0Y688|ensembl:ENSP00000269260.2	psi-mi:syi_fratt(display_long)|uniprotkb:ileS(gene name)|psi-mi:ileS(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0915c(locus name)	psi-mi:arrb2_human(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:ARRB2(gene name)|psi-mi:ARRB2(display_short)|uniprotkb:ARB2(gene name synonym)|uniprotkb:ARR2(gene name synonym)|uniprotkb:Non-visual arrestin-3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808736|imex:IM-13779-1293	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004822""(isoleucine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006428""(isoleucyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|refseq:YP_169912.1|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR023585|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR033708|refseq:WP_003020930.1|interpro:IPR050081"	"refseq:NP_004304.1|refseq:NP_945355.1|refseq:NP_001244259.1|refseq:NP_001244260.1|refseq:NP_001244257.1|refseq:NP_001244258.1|ensembl:ENSG00000141480.18(gene)|ensembl:ENST00000269260.7(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0002029""(desensitization of G protein-coupled receptor signaling pathway)|go:""GO:0002031""(G protein-coupled receptor internalization)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007212""(G protein-coupled dopamine receptor signaling pathway)|go:""GO:0007628""(adult walking behavior)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0015031""(protein transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019899""(enzyme binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031701""(angiotensin receptor binding)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032226""(positive regulation of synaptic transmission, dopaminergic)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|reactome:R-HSA-5674135|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043422""(protein kinase B binding)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0098794""(postsynapse)|go:""GO:0098926""(postsynaptic signal transduction)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000727""(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P32121|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-456926|reactome:R-HSA-5099900|reactome:R-HSA-5635838|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9839389|refseq:NP_001316993.1|dip:DIP-40089N|panther:PTHR11792(orthology-group)|ensembl:ENSP00000269260.2|ensembl:ENST00000346341.6|ensembl:ENSP00000341895.2|ensembl:ENST00000381488.10|ensembl:ENSP00000370898.6|ensembl:ENST00000412477.7|ensembl:ENSP00000403701.3"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:rpieOG/gJjPi10d8iXowKjzAafg177416	rogid:MY34flMH9cdhPtMLGYOQtoQyr2U9606	intact-crc:214C7BB0A6CDE1B0|rigid:5bsP2EjMr4T6SI+faEJr3eBbkAI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P32121	uniprotkb:Q5NHX5	intact:EBI-714559|uniprotkb:Q0Z8D3|uniprotkb:Q2PP19|uniprotkb:Q6ICT3|uniprotkb:Q8N7Y2|uniprotkb:Q9UEQ6|uniprotkb:B7WPL3|uniprotkb:B5B0C0|uniprotkb:D3DTK2|intact:EBI-28974065|uniprotkb:B4DLW0|uniprotkb:H0Y688|ensembl:ENSP00000269260.2	intact:EBI-2801674|uniprotkb:A0A0G2RNV9	psi-mi:arrb2_human(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:ARRB2(gene name)|psi-mi:ARRB2(display_short)|uniprotkb:ARB2(gene name synonym)|uniprotkb:ARR2(gene name synonym)|uniprotkb:Non-visual arrestin-3(gene name synonym)	psi-mi:q5nhx5_fratt(display_long)|uniprotkb:cdsA(gene name)|psi-mi:cdsA(display_short)|uniprotkb:FTT_0318(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808743|imex:IM-13779-1292	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004304.1|refseq:NP_945355.1|refseq:NP_001244259.1|refseq:NP_001244260.1|refseq:NP_001244257.1|refseq:NP_001244258.1|ensembl:ENSG00000141480.18(gene)|ensembl:ENST00000269260.7(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0002029""(desensitization of G protein-coupled receptor signaling pathway)|go:""GO:0002031""(G protein-coupled receptor internalization)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007212""(G protein-coupled dopamine receptor signaling pathway)|go:""GO:0007628""(adult walking behavior)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0015031""(protein transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019899""(enzyme binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031701""(angiotensin receptor binding)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032226""(positive regulation of synaptic transmission, dopaminergic)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|reactome:R-HSA-5674135|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043422""(protein kinase B binding)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0098794""(postsynapse)|go:""GO:0098926""(postsynaptic signal transduction)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000727""(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P32121|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-456926|reactome:R-HSA-5099900|reactome:R-HSA-5635838|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9839389|refseq:NP_001316993.1|dip:DIP-40089N|panther:PTHR11792(orthology-group)|ensembl:ENSP00000269260.2|ensembl:ENST00000346341.6|ensembl:ENSP00000341895.2|ensembl:ENST00000381488.10|ensembl:ENSP00000370898.6|ensembl:ENST00000412477.7|ensembl:ENSP00000403701.3"	"interpro:IPR000374(Phosphatidate cytidylyltransferase)|refseq:YP_169367.1|go:""GO:0004605""(phosphatidate cytidylyltransferase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0016024""(CDP-diacylglycerol biosynthetic process)|refseq:WP_003021609.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:MY34flMH9cdhPtMLGYOQtoQyr2U9606	rogid:j4nia2AICT6hhJFTrk/Er4tDCe8177416	intact-crc:29E9A4B0A7E4BBAC|rigid:I8sHJkUtQ6e5anu8h8jsfuYhiZ8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96DX5	uniprotkb:Q5NG37	intact:EBI-745641|uniprotkb:Q9NWS5|uniprotkb:Q9Y4T3|uniprotkb:A8K8A5|intact:EBI-2349899|uniprotkb:Q9BVF5|ensembl:ENSP00000369855.4	intact:EBI-2797809	psi-mi:asb9_human(display_long)|uniprotkb:ASB9(gene name)|psi-mi:ASB9(display_short)	psi-mi:q5ng37_fratt(display_long)|uniprotkb:FTT_1020c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808729|imex:IM-13779-1291	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001026909.1|refseq:NP_001162003.1|refseq:NP_076992.1|refseq:NP_001162002.1|refseq:XP_005274503.1|dip:DIP-52905N|ensembl:ENSG00000102048.16(gene)|ensembl:ENST00000380488.9(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031466""(Cul5-RING ubiquitin ligase complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR036036|interpro:IPR036770|interpro:IPR037333|interpro:IPR051573|mint:Q96DX5|rcsb pdb:3D9H|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:6V9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|panther:PTHR24136(orthology-group)"	"go:""GO:0016020""(membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR002293(Amino acid/polyamine transporter I)|refseq:YP_170005.1|interpro:IPR052962"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ptKNzNqGuV3MO9/nIT6RI+w/Jtk9606	rogid:hnC0KlMIAIhhl1F4hxpRqEZhwyA177416	intact-crc:F198F817DAC5460D|rigid:vFS1omV5+5zqeH8ry4cVAicf8zY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49407	uniprotkb:Q5NET8	intact:EBI-743313|uniprotkb:O75625|uniprotkb:O75630|uniprotkb:Q2PP20|uniprotkb:Q9BTK8|intact:EBI-2561130|uniprotkb:B6V9G8|ensembl:ENSP00000409581.2	intact:EBI-2797750|uniprotkb:A0A0G2RM76	psi-mi:arrb1_human(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:ARR1(gene name synonym)|uniprotkb:Non-visual arrestin-2(gene name synonym)	psi-mi:q5net8_fratt(display_long)|uniprotkb:hrpA(gene name)|psi-mi:hrpA(display_short)|uniprotkb:FTT_1524c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808757|imex:IM-13779-1295	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004032.2|refseq:NP_064647.1|dip:DIP-29979N|ensembl:ENSG00000137486.17(gene)|ensembl:ENST00000420843.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002031""(G protein-coupled receptor internalization)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0015031""(protein transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031143""(pseudopodium)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031701""(angiotensin receptor binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:1990763""(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P49407|rcsb pdb:2IV8|rcsb pdb:6PWC|rcsb pdb:6TKO|rcsb pdb:6UP7|rcsb pdb:7R0C|rcsb pdb:7R0J|rcsb pdb:7SRS|rcsb pdb:8AS2|rcsb pdb:8AS3|rcsb pdb:8AS4|rcsb pdb:8JRV|rcsb pdb:8WRZ|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-456926|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9839389|panther:PTHR11792(orthology-group)|ensembl:ENST00000360025.7|ensembl:ENSP00000353124.3|ensembl:ENSP00000409581.2"	"go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170454.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR024590|interpro:IPR010222(RNA helicase, ATP-dependent DEAH box, HrpA type)|interpro:IPR027417|refseq:WP_003022403.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:UNYbZY5saRx8CwJ8Jwt3QtjXgj09606	rogid:dwTrOZ+V/pe0RndqVFMFAdvwFAM177416	intact-crc:3422B7C9AF4FB999|rigid:DN+5XlExf3qjFBamZt7hVWy2xxw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NWB6	uniprotkb:Q5NH02	intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059.3	intact:EBI-2798386|uniprotkb:A0A0G2RM67	psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short)	psi-mi:q5nh02_fratt(display_long)|uniprotkb:prsA(gene name)|psi-mi:prsA(display_short)|uniprotkb:Phosphoribosyl diphosphate synthase(gene name synonym)|uniprotkb:Phosphoribosyl pyrophosphate synthase(gene name synonym)|uniprotkb:prs(gene name synonym)|uniprotkb:5-phospho-D-ribosyl alpha-1-diphosphate synthase(gene name synonym)|uniprotkb:FTT_0674(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808791|imex:IM-13779-1297	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060481.3|ensembl:ENSG00000134884.15(gene)|ensembl:ENST00000400198.8(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0045296""(cadherin binding)|interpro:IPR033371|mint:Q9NWB6|panther:PTHR31711(orthology-group)"	"interpro:IPR037515|go:""GO:0000287""(magnesium ion binding)|go:""GO:0002189""(ribose phosphate diphosphokinase complex)|go:""GO:0004749""(ribose phosphate diphosphokinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006015""(5-phosphoribose 1-diphosphate biosynthetic process)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0009156""(ribonucleoside monophosphate biosynthetic process)|go:""GO:0016301""(kinase activity)|interpro:IPR029057|interpro:IPR029099|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|refseq:YP_169690.1|interpro:IPR000836(Phosphoribosyltransferase)|refseq:WP_003020454.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606	rogid:tcdiy2D/pZAKsU2ELS9FdnaNChI177416	intact-crc:4D5236D113370467|rigid:OpVBYefJHFY3arstgUMshU+Dv7I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHT8	uniprotkb:Q4LE39	intact:EBI-2806309	intact:EBI-2680990|uniprotkb:Q86UX1|uniprotkb:Q5T2C5|uniprotkb:Q9NZB6|uniprotkb:Q9NYU3|uniprotkb:Q5T2C6|uniprotkb:Q5T2C3|uniprotkb:A1L465|uniprotkb:Q5HY99|uniprotkb:Q9NZG4|uniprotkb:Q86WR4|uniprotkb:Q9UF62|uniprotkb:Q9P2W4|uniprotkb:Q9H915|uniprotkb:Q5T2C2|uniprotkb:Q6P600|uniprotkb:Q3MHV4|uniprotkb:Q5T2C4|uniprotkb:Q9Y6E1|ensembl:ENSP00000264183.3|ensembl:ENSP00000355562.2	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	psi-mi:ari4b_human(display_long)|uniprotkb:BRCAA1(gene name synonym)|uniprotkb:RBBP1L1(gene name synonym)|uniprotkb:RBP1L1(gene name synonym)|uniprotkb:SAP180(gene name synonym)|uniprotkb:180 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Breast cancer-associated antigen BRCAA1(gene name synonym)|uniprotkb:Histone deacetylase complex subunit SAP180(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 1-like 1(gene name synonym)|uniprotkb:ARID4B(gene name)|psi-mi:ARID4B(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808778|imex:IM-13779-1299	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	"refseq:XP_011542514.1|refseq:NP_001193723.1|refseq:NP_057458.4|refseq:NP_112739.2|ensembl:ENSG00000054267.22(gene)|ensembl:ENST00000264183.9(transcript)|ensembl:ENST00000366603.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070822""(Sin3-type complex)|go:""GO:0071514""(genomic imprinting)|go:""GO:0097368""(establishment of Sertoli cell barrier)|go:""GO:1902455""(negative regulation of stem cell population maintenance)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR002999(Tudor)|interpro:IPR012603(RBB1NT)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR028853|interpro:IPR036431|interpro:IPR047474|interpro:IPR047476|interpro:IPR051232|mint:Q4LE39|rcsb pdb:7DM4|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|panther:PTHR13964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	rogid:qvmc05fd/Hu9k0HLB3gRG4ndRp89606	intact-crc:5319BE49AC78A5C4|rigid:V8PAFia0P0INAjxw7O+DSP3fxjY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZ32	uniprotkb:Q79RC1	intact:EBI-2559426|ensembl:ENSP00000254286.4|uniprotkb:Q9H9Y5|uniprotkb:Q9NWY2	intact:EBI-2800505	psi-mi:arp10_human(display_long)|uniprotkb:ACTR10(gene name)|psi-mi:ACTR10(display_short)|uniprotkb:ACTR11(gene name synonym)|uniprotkb:ARP11(gene name synonym)|uniprotkb:Actin-related protein 11(gene name synonym)|uniprotkb:ARP10(gene name synonym)	psi-mi:q79rc1_fratl(display_long)|uniprotkb:manB(gene name)|psi-mi:manB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808764|imex:IM-13779-1298	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000131966.14(gene)|ensembl:ENST00000254286.9(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0098958""(retrograde axonal transport of mitochondrion)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR004000(Actin/actin-like)|interpro:IPR043129|mint:Q9NZ32|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|refseq:NP_060947.1|panther:PTHR11937(orthology-group)"	"refseq:WP_003022277.1|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004615""(phosphomannomutase activity)|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0008966""(phosphoglucosamine mutase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|interpro:IPR036900|interpro:IPR050060"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zP8oC2X4zksg1YC89SF2yerpa6I9606	rogid:VditS6r1AnxfAC5K+EjyPlNcTkE119856	intact-crc:E8214C2C9A11E4F2|rigid:0s50rHFEceGtFzKU+jXoQ75Ls70	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF74	uniprotkb:Q4LE39	intact:EBI-2796785|uniprotkb:A0A0G2RND4	intact:EBI-2680990|uniprotkb:Q86UX1|uniprotkb:Q5T2C5|uniprotkb:Q9NZB6|uniprotkb:Q9NYU3|uniprotkb:Q5T2C6|uniprotkb:Q5T2C3|uniprotkb:A1L465|uniprotkb:Q5HY99|uniprotkb:Q9NZG4|uniprotkb:Q86WR4|uniprotkb:Q9UF62|uniprotkb:Q9P2W4|uniprotkb:Q9H915|uniprotkb:Q5T2C2|uniprotkb:Q6P600|uniprotkb:Q3MHV4|uniprotkb:Q5T2C4|uniprotkb:Q9Y6E1|ensembl:ENSP00000264183.3|ensembl:ENSP00000355562.2	psi-mi:q5nf74_fratt(display_long)|uniprotkb:tktA(gene name)|psi-mi:tktA(display_short)|uniprotkb:FTT_1369c(locus name)	psi-mi:ari4b_human(display_long)|uniprotkb:BRCAA1(gene name synonym)|uniprotkb:RBBP1L1(gene name synonym)|uniprotkb:RBP1L1(gene name synonym)|uniprotkb:SAP180(gene name synonym)|uniprotkb:180 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Breast cancer-associated antigen BRCAA1(gene name synonym)|uniprotkb:Histone deacetylase complex subunit SAP180(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 1-like 1(gene name synonym)|uniprotkb:ARID4B(gene name)|psi-mi:ARID4B(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808771|imex:IM-13779-1296	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170318.1|rcsb pdb:3KOM|interpro:IPR049557|interpro:IPR029061|interpro:IPR033247|refseq:WP_003022170.1"	"refseq:XP_011542514.1|refseq:NP_001193723.1|refseq:NP_057458.4|refseq:NP_112739.2|ensembl:ENSG00000054267.22(gene)|ensembl:ENST00000264183.9(transcript)|ensembl:ENST00000366603.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070822""(Sin3-type complex)|go:""GO:0071514""(genomic imprinting)|go:""GO:0097368""(establishment of Sertoli cell barrier)|go:""GO:1902455""(negative regulation of stem cell population maintenance)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR002999(Tudor)|interpro:IPR012603(RBB1NT)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR028853|interpro:IPR036431|interpro:IPR047474|interpro:IPR047476|interpro:IPR051232|mint:Q4LE39|rcsb pdb:7DM4|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|panther:PTHR13964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7/L5KHUX/qskeOkVPcgsIoOrmVU177416	rogid:qvmc05fd/Hu9k0HLB3gRG4ndRp89606	intact-crc:00EE1049AFFB7A18|rigid:CgykqSRYkgFdbVFucWg4mwNSWqs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IWT0	uniprotkb:Q5NHN7	intact:EBI-2808825|uniprotkb:Q8IWS9|uniprotkb:Q6PDA1|uniprotkb:Q5TGK5|uniprotkb:Q8NEV6|uniprotkb:Q8NEV7|ensembl:ENSP00000417677.2	intact:EBI-2802363|uniprotkb:A0A0G2RLZ9	psi-mi:arch_human(display_long)|uniprotkb:ZBTB8OS(gene name)|psi-mi:ZBTB8OS(display_short)|uniprotkb:ARCH(gene name synonym)|uniprotkb:Protein ZBTB8OS(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing opposite strand protein 8(gene name synonym)	psi-mi:q5nhn7_fratt(display_long)|uniprotkb:gcvP2(gene name)|psi-mi:gcvP2(display_short)|uniprotkb:FTT_0410(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808834|imex:IM-13779-1301	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001295065.1|refseq:NP_001295068.1|refseq:NP_848642.1|ensembl:ENSG00000176261.16(gene)|ensembl:ENST00000468695.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006388""(tRNA splicing, via endonucleolytic cleavage and ligation)|go:""GO:0046872""(metal ion binding)|go:""GO:0072669""(tRNA-splicing ligase complex)|interpro:IPR002804(Protein of unknown function DUF101)|interpro:IPR023572|interpro:IPR036820|reactome:R-HSA-6784531|dip:DIP-61031N|panther:PTHR12682(orthology-group)"	"interpro:IPR020581|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:YP_169455.1|refseq:WP_011242235.1|go:""GO:0004375""(""glycine dehydrogenase (decarboxylating) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0016594""(glycine binding)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR049315|interpro:IPR049316"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:j+gNQ+lsfypCH7r4d3s9Pjf5c6s9606	rogid:PrvVzFJYuRfdefUo4kpPUAO8pgg177416	intact-crc:C372203B20F6B942|rigid:Ky0cMm3P698PBwQiEmfDcSowTak	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEE2	uniprotkb:P84077	intact:EBI-2801846	intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102.5|ensembl:ENSP00000514653.1|ensembl:ENSP00000514654.1|ensembl:ENSP00000514657.1	psi-mi:ch10_fratt(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:FTT_1695(locus name)	psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808818|imex:IM-13779-1303	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:YP_170600.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|refseq:WP_003022662.1|interpro:IPR037124"	"panther:PTHR11711(orthology-group)|efo:""Orphanet:98892""|ensembl:ENSG00000143761.17(gene)|ensembl:ENST00000272102.10(transcript)|ensembl:ENST00000470558.5(transcript)|ensembl:ENST00000478336.5(transcript)|ensembl:ENST00000478424.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0002090""(regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030017""(sarcomere)|go:""GO:0031252""(cell leading edge)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0043005""(neuron projection)|go:""GO:0060292""(long-term synaptic depression)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097061""(dendritic spine organization)|go:""GO:0098586""(cellular response to virus)|go:""GO:1990386""(mitotic cleavage furrow ingression)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR024156|interpro:IPR027417|interpro:IPR045872|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7DN8|rcsb pdb:7DN9|rcsb pdb:7MGE|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9U|rcsb pdb:8D9W|rcsb pdb:8SDW|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505|reactome:R-HSA-9845576|refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7eJ39xoXB4aTg7AgU9wnnxinSoE177416	rogid:zray9asm6VonxpuJpv0dRBspPt89606	intact-crc:E320BB012905E5CF|rigid:7arlRCpTRdNGTzPEUE4JrH28wmM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P53367	uniprotkb:Q5NGF9	intact:EBI-2808808|uniprotkb:Q9Y2X6|uniprotkb:Q3SYL4|uniprotkb:Q2M2X4|ensembl:ENSP00000296557.4|ensembl:ENSP00000395083.2|uniprotkb:B4DS69	intact:EBI-2796712|uniprotkb:A0A0G2RMW7	psi-mi:arfp1_human(display_long)|uniprotkb:ARFIP1(gene name)|psi-mi:ARFIP1(display_short)|uniprotkb:ADP-ribosylation factor-interacting protein 1(gene name synonym)	psi-mi:q5ngf9_fratt(display_long)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:FTT_0886(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808805|imex:IM-13779-1300	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011530171.1|refseq:NP_001020764.1|refseq:NP_001020766.1|refseq:NP_055262.1|refseq:XP_011530172.1|refseq:NP_001274360.1|refseq:NP_001274361.1|refseq:NP_001274362.1|ensembl:ENSG00000164144.16(gene)|ensembl:ENST00000353617.7(transcript)|ensembl:ENST00000451320.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0050708""(regulation of protein secretion)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:1905280""(negative regulation of retrograde transport, endosome to Golgi)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|mint:P53367|panther:PTHR12141(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|refseq:YP_169883.1|interpro:IPR027417|refseq:WP_003020876.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KEZ1eqEIdGfgFYIlc3WlNvqg9/89606	rogid:OSkw64bDGErXabpL9In6RSfdCEQ177416	intact-crc:192F8402A5E3F736|rigid:ygw1mbMF0VqoWOPq6hT/hxOZWFM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NET8	uniprotkb:P53365	intact:EBI-2797750|uniprotkb:A0A0G2RM76	intact:EBI-638194|uniprotkb:D3DQT5|uniprotkb:B4E306|uniprotkb:B4DX86|ensembl:ENSP00000254584.2|ensembl:ENSP00000379998.3	psi-mi:q5net8_fratt(display_long)|uniprotkb:hrpA(gene name)|psi-mi:hrpA(display_short)|uniprotkb:FTT_1524c(locus name)	psi-mi:arfp2_human(display_long)|uniprotkb:ADP-ribosylation factor-interacting protein 2(gene name synonym)|uniprotkb:Partner of RAC1(gene name synonym)|uniprotkb:ARFIP2(gene name)|psi-mi:ARFIP2(display_short)|uniprotkb:POR1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808798|imex:IM-13779-1302	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170454.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR024590|interpro:IPR010222(RNA helicase, ATP-dependent DEAH box, HrpA type)|interpro:IPR027417|refseq:WP_003022403.1"	"refseq:NP_001229784.1|refseq:NP_036534.1|refseq:NP_001229785.1|refseq:XP_005252897.1|ensembl:ENSG00000132254.13(gene)|ensembl:ENST00000254584.6(transcript)|ensembl:ENST00000396777.8(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0001726""(ruffle)|go:""GO:0005525""(GTP binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031529""(ruffle organization)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0034497""(protein localization to phagophore assembly site)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0140090""(membrane curvature sensor activity)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|mint:P53365|rcsb pdb:1I49|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:4DCN|reactome:R-HSA-6811440|panther:PTHR12141(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dwTrOZ+V/pe0RndqVFMFAdvwFAM177416	rogid:q3QMUWlBIW82Szrv9jbMR6ikOZg9606	intact-crc:75B6EEC240A91FDD|rigid:zDs3yj5F88dn+37lWelj0DUWZvE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92482	uniprotkb:Q5NGA0	intact:EBI-2808854|uniprotkb:Q6FGW6|uniprotkb:B2RE16|uniprotkb:Q6FGT2|uniprotkb:O00108|uniprotkb:A8K843|uniprotkb:D3DRL3|ensembl:ENSP00000297991.4	intact:EBI-2800784|uniprotkb:A0A0G2RQ90	psi-mi:aqp3_human(display_long)|uniprotkb:AQP3(gene name)|psi-mi:AQP3(display_short)|uniprotkb:Aquaglyceroporin-3(gene name synonym)	psi-mi:q5nga0_fratt(display_long)|uniprotkb:rhlE(gene name)|psi-mi:rhlE(display_short)|uniprotkb:FTT_0952(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808863|imex:IM-13779-1304	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004916.1|ensembl:ENSG00000165272.16(gene)|ensembl:ENST00000297991.6(transcript)|go:""GO:0002684""(positive regulation of immune system process)|go:""GO:0002931""(response to ischemia)|go:""GO:0003091""(renal water homeostasis)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006833""(water transport)|go:""GO:0015204""(urea transmembrane transporter activity)|go:""GO:0015250""(water channel activity)|go:""GO:0015254""(glycerol channel activity)|go:""GO:0015793""(glycerol transmembrane transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0033280""(response to vitamin D)|go:""GO:0042476""(odontogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0045616""(regulation of keratinocyte differentiation)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0070295""(renal water absorption)|go:""GO:0071456""(cellular response to hypoxia)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023275|interpro:IPR050363|reactome:R-HSA-432040|reactome:R-HSA-432047|reactome:R-HSA-9725554|refseq:NP_001305073.1|panther:PTHR43829(orthology-group)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|refseq:YP_169942.1|interpro:IPR027417|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0016787""(hydrolase activity)|refseq:WP_003021019.1|interpro:IPR050079"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wQYbRo4WMo5r5XEyhOpcEC1xVa09606	rogid:IIfGlhg/cfRi88KrQNS1limaOMY177416	intact-crc:D324131E6E632875|rigid:Yud/lL+/0wN7lxakXBMh+Sq0dFM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N6S5	uniprotkb:Q5NEB4	intact:EBI-2808844|uniprotkb:Q7Z4G7|uniprotkb:B2RDS6|ensembl:ENSP00000315357.5|intact:EBI-28975285	intact:EBI-2797653|uniprotkb:A0A0G2RPR1	psi-mi:ar6p6_human(display_long)|uniprotkb:ARL6IP6(gene name)|psi-mi:ARL6IP6(display_short)|uniprotkb:PFAAP1(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 1(gene name synonym)	psi-mi:q5neb4_fratt(display_long)|uniprotkb:yegQ(gene name)|psi-mi:yegQ(display_short)|uniprotkb:FTT_1726(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808841|imex:IM-13779-1306	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000177917.12(gene)|ensembl:ENST00000326446.10(transcript)|go:""GO:0005637""(nuclear inner membrane)|interpro:IPR029383|mint:Q8N6S5|refseq:NP_689735.1|efo:""Orphanet:1556""|panther:PTHR28640(orthology-group)"	"interpro:IPR001539(Peptidase U32)|refseq:YP_170628.1|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|interpro:IPR032525|refseq:WP_003022701.1|interpro:IPR051454"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UrQYB2/lPYvIbJ0LgJTWbJI1//Q9606	rogid:V8v+igazfnHs0EcKm43UGRWNmrY177416	intact-crc:A9A7277E79BC5AC1|rigid:/U3ubZY02x4mxUrhqRa9C7T+dZo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95236	uniprotkb:Q5NGF1	intact:EBI-2622258|uniprotkb:Q9BQA3|uniprotkb:B1AHI5|uniprotkb:B1AHI4|uniprotkb:Q9BQ82|uniprotkb:Q5U5N4|ensembl:ENSP00000344577.2	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	psi-mi:apol3_human(display_long)|uniprotkb:Apolipoprotein L-III(gene name synonym)|uniprotkb:TNF-inducible protein CG12-1(gene name synonym)|uniprotkb:APOL3(gene name)|psi-mi:APOL3(display_short)	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808870|imex:IM-13779-1307	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055164.1|refseq:NP_085147.1|refseq:NP_663614.1|refseq:XP_006724387.1|refseq:NP_663615.1|refseq:NP_663616.1|refseq:NP_663617.1|ensembl:ENSG00000128284.21(gene)|ensembl:ENST00000349314.7(transcript)|go:""GO:0005319""(lipid transporter activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0006954""(inflammatory response)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0042157""(lipoprotein metabolic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|interpro:IPR008405(Apolipoprotein L)|refseq:XP_006724388.1|refseq:XP_016884441.1|panther:PTHR14096(orthology-group)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Iqurc66QUo7OVUtTMnjwn3pdr9w9606	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	intact-crc:CCE0BFBC2206CCF8|rigid:IXbobcZIWBpGlJ+pDv+WS+WR4Mw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96GX9	uniprotkb:Q79RC4	intact:EBI-359248|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3|ensembl:ENSP00000379133.3	intact:EBI-2808877	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	psi-mi:q79rc4_fratl(display_long)|uniprotkb:wbtM(gene name)|psi-mi:wbtM(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808881|imex:IM-13779-1305	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057041.2|ensembl:ENSG00000149089.13(gene)|ensembl:ENST00000395787.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0019509""(L-methionine salvage from methylthioadenosine)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046570""(methylthioribulose 1-phosphate dehydratase activity)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|panther:PTHR10640(orthology-group)"	"interpro:IPR005888(dTDP-glucose 4,6-dehydratase)|interpro:IPR016040(""NAD(P)-binding"")|go:""GO:0008460""(dTDP-glucose 4,6-dehydratase activity)|go:""GO:0009225""(nucleotide-sugar metabolic process)|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	rogid:PUwPaxy4EFj0xkEwxXURsoFBpSc119856	intact-crc:1CABB4F51EA3405E|rigid:t5jt2pp1jdhCjd85MIjYup6GWXs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94973	uniprotkb:Q5NH38	intact:EBI-1642835|uniprotkb:O75403|uniprotkb:Q96SI8|uniprotkb:Q53ET1|ensembl:ENSP00000413234.3	intact:EBI-2797227|uniprotkb:A0A0G2RP54	psi-mi:ap2a2_human(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:q5nh38_fratt(display_long)|uniprotkb:hflK(gene name)|psi-mi:hflK(display_short)|uniprotkb:FTT_0633(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808895|imex:IM-13779-1308	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229766.1|refseq:NP_036437.1|ensembl:ENSG00000183020.15(gene)|ensembl:ENST00000448903.7(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008289""(lipid binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR050840|mint:O94973|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-6798695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|panther:PTHR22780(orthology-group)"	"go:""GO:0016020""(membrane)|interpro:IPR001107(Band 7 protein)|interpro:IPR010201(HflK)|refseq:YP_169654.1|refseq:WP_003023444.1|interpro:IPR036013|interpro:IPR050710"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sda1msOBssgmBiU3ZfSyk3z7/jc9606	rogid:0bj8rSZ7SoJuK6iGQz/clayaUPs177416	intact-crc:F2450BF64E5FB36E|rigid:NsFZO92zutLiqgulRD9A5FDwp5s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV7	uniprotkb:O94973	intact:EBI-2796192	intact:EBI-1642835|uniprotkb:O75403|uniprotkb:Q96SI8|uniprotkb:Q53ET1|ensembl:ENSP00000413234.3	psi-mi:katg_fratt(display_long)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:FTT_0721c(locus name)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)	psi-mi:ap2a2_human(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808902|imex:IM-13779-1310	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169735.1|interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|refseq:WP_003020536.1|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)"	"refseq:NP_001229766.1|refseq:NP_036437.1|ensembl:ENSG00000183020.15(gene)|ensembl:ENST00000448903.7(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008289""(lipid binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR050840|mint:O94973|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-6798695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|panther:PTHR22780(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UVLspYdPWJwb7VPBG0xNq1Pp2KQ177416	rogid:sda1msOBssgmBiU3ZfSyk3z7/jc9606	intact-crc:ED49D4F64D38A766|rigid:phqgUFEm0mYRboj9j4phYkrcCI4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGR3	uniprotkb:Q02410	intact:EBI-2796275	intact:EBI-368690|uniprotkb:O14914|uniprotkb:O60570|uniprotkb:Q5VYR8|intact:EBI-8840163|intact:EBI-8840293|ensembl:ENSP00000265381.3	psi-mi:seca_fratt(display_long)|uniprotkb:FTT_0769(locus name)|uniprotkb:secA(gene name)|psi-mi:secA(display_short)	psi-mi:apba1_human(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808888|imex:IM-13779-1309	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0017038""(protein import)|go:""GO:0031522""(cell envelope Sec protein transport complex)|go:""GO:0043952""(protein transport by the Sec complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0065002""(intracellular protein transmembrane transport)|refseq:YP_169779.1|interpro:IPR004027(SEC-C motif)|interpro:IPR000185(SecA protein)|interpro:IPR020937|interpro:IPR011115(SecA DEAD-like)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR044722|interpro:IPR027417|refseq:WP_011242256.1|interpro:IPR036266|interpro:IPR036670"	"refseq:XP_005252025.1|refseq:NP_001154.2|ensembl:ENSG00000107282.9(gene)|ensembl:ENST00000265381.7(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007155""(cell adhesion)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007399""(nervous system development)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008088""(axo-dendritic transport)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0014047""(glutamate secretion)|go:""GO:0014051""(gamma-aminobutyric acid secretion)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0043197""(dendritic spine)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048787""(presynaptic active zone membrane)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099171""(presynaptic modulation of chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR051230|mint:Q02410|rcsb pdb:1AQC|rcsb pdb:1U37|rcsb pdb:1U38|rcsb pdb:1U39|rcsb pdb:1U3B|rcsb pdb:1X11|rcsb pdb:1X45|rcsb pdb:1Y7N|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:XP_011516919.1|refseq:XP_016870159.1|panther:PTHR12345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:c80pRjALHg9VjvniwOaxVtBGz4w177416	rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606	intact-crc:7787DF97B1E2419E|rigid:7poWXSXFx/b35rqza3td2BggN5M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIJ1	uniprotkb:P08133	intact:EBI-2801762	intact:EBI-352541|uniprotkb:B7Z8A7|uniprotkb:E9PGK1|uniprotkb:Q6ZT79|uniprotkb:D3DQH4|ensembl:ENSP00000346550.5	psi-mi:q5nij1_fratt(display_long)|uniprotkb:sucA(gene name)|psi-mi:sucA(display_short)|uniprotkb:FTT_0076(locus name)	psi-mi:anxa6_human(display_long)|uniprotkb:ANXA6(gene name)|psi-mi:ANXA6(display_short)|uniprotkb:ANX6(gene name synonym)|uniprotkb:Annexin-6(gene name synonym)|uniprotkb:Annexin VI(gene name synonym)|uniprotkb:Lipocortin VI(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:p70(gene name synonym)|uniprotkb:Protein III(gene name synonym)|uniprotkb:Chromobindin-20(gene name synonym)|uniprotkb:67 kDa calelectrin(gene name synonym)|uniprotkb:Calphobindin-II(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808937|imex:IM-13779-1313	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031717|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|refseq:YP_169151.1|go:""GO:0004591""(""oxoglutarate dehydrogenase (succinyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|interpro:IPR029061|interpro:IPR042179"	"refseq:NP_001146.2|refseq:NP_001180473.1|ensembl:ENSG00000197043.15(gene)|ensembl:ENST00000354546.10(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006937""(regulation of muscle contraction)|go:""GO:0008289""(lipid binding)|go:""GO:0012506""(vesicle membrane)|go:""GO:0015276""(ligand-gated monoatomic ion channel activity)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051283""(negative regulation of sequestering of calcium ion)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097190""(apoptotic signaling pathway)|interpro:IPR001464(Annexin)|interpro:IPR002393(Annexin, type VI)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08133|rcsb pdb:1M9I|reactome:R-HSA-445355|panther:PTHR10502(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dQc/mmfwgUYZL0zzhIJG4HqrrDA177416	rogid:+1oKdgl2a0haedrMSJ8au35MF8c9606	intact-crc:4C85BD60EA48A525|rigid:4c4cnX3yl/FKr9193LEDLEGvWRc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEX2	uniprotkb:P20073	intact:EBI-2801291|uniprotkb:A0A0G2RMB1	intact:EBI-2338704|uniprotkb:Q5F2H3|uniprotkb:Q5T0M6|uniprotkb:Q5T0M7|ensembl:ENSP00000362010.4|intact:EBI-28973842	psi-mi:q5nex2_fratt(display_long)|uniprotkb:aceE(gene name)|psi-mi:aceE(display_short)|uniprotkb:FTT_1485c(locus name)	psi-mi:anxa7_human(display_long)|uniprotkb:ANXA7(gene name)|psi-mi:ANXA7(display_short)|uniprotkb:ANX7(gene name synonym)|uniprotkb:SNX(gene name synonym)|uniprotkb:Annexin-7(gene name synonym)|uniprotkb:Annexin VII(gene name synonym)|uniprotkb:Synexin(gene name synonym)|uniprotkb:OK/SW-cl.95(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808930|imex:IM-13779-1315	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004660(2-oxo-acid dehydrogenase E1 component homodimeric type)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005474(Transketolase, N-terminal)|refseq:YP_170420.1|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|interpro:IPR029061|refseq:WP_003022343.1|interpro:IPR035807|interpro:IPR041621|interpro:IPR051157"	"refseq:NP_001147.1|refseq:NP_004025.1|refseq:XP_016871651.1|refseq:XP_016871652.1|ensembl:ENSG00000138279.16(gene)|ensembl:ENST00000372919.8(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006914""(autophagy)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P20073|rcsb pdb:8W5S|ensembl:ENSP00000362010.4|ensembl:ENST00000372921.10|ensembl:ENSP00000362012.4|panther:PTHR10502(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:syWtCNlO8E27+vx4xnxn4ZOFhJA177416	rogid:ad3I49rhRoZ0hG8ruDgSQWocVuw9606	intact-crc:6447FFA3AE8D8D21|rigid:QdQbh4hAs9Ibf141NYBObKd/ip4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10567	uniprotkb:Q5NGW2	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	intact:EBI-2796474|uniprotkb:A0A0G2RND5	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:q5ngw2_fratt(display_long)|uniprotkb:FTT_0715(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808923|imex:IM-13779-1312	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0004568""(chitinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR029070|refseq:YP_169730.1|interpro:IPR003610(Carbohydrate-binding family V/XII)|interpro:IPR011583(Chitinase II)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_003020524.1|interpro:IPR036116|interpro:IPR036573|interpro:IPR050314"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	rogid:hPHdF34TD5FCXE5bWyEmg/dd7sg177416	intact-crc:C79B11761F96F1AF|rigid:CpRumh+CdP7LMxYPS0HpxB74KRs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10567	uniprotkb:Q5NIB1	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	intact:EBI-2796726	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:bamb_fratt(display_long)|uniprotkb:bamB(gene name)|psi-mi:bamB(display_short)|uniprotkb:FTT_0165c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808916|imex:IM-13779-1314	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"go:""GO:0009279""(cell outer membrane)|go:""GO:0043165""(Gram-negative-bacterium-type cell outer membrane assembly)|go:""GO:0051205""(protein insertion into membrane)|interpro:IPR017687(Outer membrane assembly lipoprotein YfgL)|interpro:IPR018391|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|refseq:YP_169231.1|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR002372(Pyrrolo-quinoline quinone)|refseq:WP_003019949.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	rogid:W1n/uA7DmeRwwC7YOi9s2SlbQPk177416	intact-crc:9F1ABF761F7713FC|rigid:ZQyMsABBZ2QNXaJxhBuO3VWAZCU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75843	uniprotkb:Q5NI89	intact:EBI-373637|uniprotkb:O75504|uniprotkb:D3DS51|ensembl:ENSP00000312442.5|ensembl:ENSP00000380309.3	intact:EBI-2796250	psi-mi:ap1g2_human(display_long)|uniprotkb:AP1G2(gene name)|psi-mi:AP1G2(display_short)|uniprotkb:Gamma2-adaptin(gene name synonym)	psi-mi:q5ni89_fratt(display_long)|uniprotkb:lysS(gene name synonym)|uniprotkb:lysU(gene name)|psi-mi:lysU(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0192(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808909|imex:IM-13779-1311	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR22780(orthology-group)|refseq:NP_003908.1|refseq:XP_005268229.1|refseq:XP_005268230.1|ensembl:ENSG00000213983.12(gene)|ensembl:ENST00000308724.9(transcript)|ensembl:ENST00000397120.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030133""(transport vesicle)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0045202""(synapse)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|interpro:IPR050840|mint:O75843|rcsb pdb:2E9G|rcsb pdb:2YMT|rcsb pdb:3ZHF|rcsb pdb:4BCX|reactome:R-HSA-432720|dip:DIP-31185N"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|interpro:IPR044136|refseq:YP_169253.1|interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:kqOQ44wfiFq2YxrDbVBvofbl9E89606	rogid:4e6LdrlEB4PMi+b0yLmkVagonC4177416	intact-crc:7168642C58849C14|rigid:YOFe41ARpR/vWBKtKVCzoTZPPh8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50995	uniprotkb:Q5NHS4	intact:EBI-715243|uniprotkb:B4DVE7|intact:EBI-10981770|ensembl:ENSP00000361305.3|ensembl:ENSP00000398610.1|ensembl:ENSP00000404412.2	intact:EBI-2798955|uniprotkb:A0A0G2RPB0	psi-mi:anx11_human(display_long)|uniprotkb:Annexin-11(gene name synonym)|uniprotkb:Annexin XI(gene name synonym)|uniprotkb:Calcyclin-associated annexin 50(gene name synonym)|uniprotkb:56 kDa autoantigen(gene name synonym)|uniprotkb:ANXA11(gene name)|psi-mi:ANXA11(display_short)|uniprotkb:ANX11(gene name synonym)	psi-mi:q5nhs4_fratt(display_long)|uniprotkb:Folylpolyglutamate synthetase(gene name synonym)|uniprotkb:Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase(gene name synonym)|uniprotkb:folC(gene name)|psi-mi:folC(display_short)|uniprotkb:Tetrahydrofolylpolyglutamate synthase(gene name synonym)|uniprotkb:FTT_0371c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808973|imex:IM-13779-1319	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:803""|ensembl:ENSG00000122359.18(gene)|ensembl:ENST00000372231.7(transcript)|ensembl:ENST00000422982.8(transcript)|ensembl:ENST00000438331.5(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006909""(phagocytosis)|go:""GO:0008429""(phosphatidylethanolamine binding)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030496""(midbody)|go:""GO:0032506""(cytokinetic process)|go:""GO:0042470""(melanosome)|go:""GO:0042581""(specific granule)|go:""GO:0042582""(azurophil granule)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0051592""(response to calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR008157(Annexin, type XI, N-terminal)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P50995|rcsb pdb:9FOF|rcsb pdb:9FOR|refseq:NP_001148.1|refseq:NP_001265336.1|refseq:NP_001265337.1|refseq:NP_001265338.1|refseq:NP_665875.1|refseq:NP_665876.1|refseq:XP_011538038.1|panther:PTHR10502(orthology-group)"	"interpro:IPR001645(Folylpolyglutamate synthetase)|interpro:IPR013221(Mur ligase, central)|refseq:YP_169418.1|go:""GO:0004326""(tetrahydrofolylpolyglutamate synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008841""(dihydrofolate synthase activity)|go:""GO:0046654""(tetrahydrofolate biosynthetic process)|go:""GO:0046656""(folic acid biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_003020032.1|interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR036565|interpro:IPR036615"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6j7B4/J0DI0LZADQ5klJQoYf7289606	rogid:yCx5zGRSAd5ahIDsKUCa0YzZPVg177416	intact-crc:3EFBBA25CA985643|rigid:a1CxwEwl5tur0SX2I21SsvnujF4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04083	uniprotkb:Q5NI96	intact:EBI-354007|ensembl:ENSP00000257497.6|ensembl:ENSP00000366109.1|uniprotkb:B5BU38	intact:EBI-2806028	psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym)	psi-mi:ddl_fratt(display_long)|uniprotkb:D-Ala-D-Ala ligase(gene name synonym)|uniprotkb:D-alanylalanine synthetase(gene name synonym)|uniprotkb:FTT_0185(locus name)|uniprotkb:ddl(gene name)|psi-mi:ddl(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808966|imex:IM-13779-1317	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000691.1|ensembl:ENSG00000135046.15(gene)|ensembl:ENST00000257497.11(transcript)|ensembl:ENST00000376911.2(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002685""(regulation of leukocyte migration)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007187""(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:""GO:0008289""(lipid binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014839""(myoblast migration involved in skeletal muscle regeneration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031514""(motile cilium)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032652""(regulation of interleukin-1 production)|go:""GO:0032717""(negative regulation of interleukin-8 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0033031""(positive regulation of neutrophil apoptotic process)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045627""(positive regulation of T-helper 1 cell differentiation)|go:""GO:0045629""(negative regulation of T-helper 2 cell differentiation)|go:""GO:0045920""(negative regulation of exocytosis)|go:""GO:0046632""(alpha-beta T cell differentiation)|mint:P04083|go:""GO:0046883""(regulation of hormone secretion)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050482""(arachidonate secretion)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071621""(granulocyte chemotaxis)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|refseq:XP_011516911.1|dip:DIP-32875N|panther:PTHR10502(orthology-group)"	"refseq:YP_169246.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR000291(D-alanine--D-alanine ligase/VANA/B/C, conserved site)|interpro:IPR005905(D-alanine--D-alanine ligase)|interpro:IPR011095(D-alanine--D-alanine ligase, C-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008716""(D-alanine-D-alanine ligase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0071555""(cell wall organization)|refseq:WP_003027426.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:QKmqz+UsAof35B/so2qKLQjn2v09606	rogid:Ofh+mb/jW5UTankYJCJcXlF58wA177416	intact-crc:54C73247A6A456FC|rigid:PwtWSS5lzCLTtUQ5T4pqpkopbXA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P07355	uniprotkb:Q5NG97	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-2808955|uniprotkb:A0A0G2RQ99	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:q5ng97_fratt(display_long)|uniprotkb:gor(gene name)|psi-mi:gor(display_short)|uniprotkb:FTT_0955c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808959|imex:IM-13779-1318	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR006322(Glutathione reductase, animal and bacterial)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|refseq:YP_169945.1|go:""GO:0004362""(""glutathione-disulfide reductase (NADPH) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0050661""(NADP binding)|refseq:WP_003021023.1|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR036188|interpro:IPR046952"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:biZgZ28/rnr4Brcut9/Trv0Y4d0177416	intact-crc:C7867C63B99CCFEF|rigid:gnoezjNO0CKAvdDb2ZsextIi01c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08133	uniprotkb:Q5NFT7	intact:EBI-352541|uniprotkb:B7Z8A7|uniprotkb:E9PGK1|uniprotkb:Q6ZT79|uniprotkb:D3DQH4|ensembl:ENSP00000346550.5	intact:EBI-2808947|uniprotkb:A0A0G2RMW9	psi-mi:anxa6_human(display_long)|uniprotkb:ANXA6(gene name)|psi-mi:ANXA6(display_short)|uniprotkb:ANX6(gene name synonym)|uniprotkb:Annexin-6(gene name synonym)|uniprotkb:Annexin VI(gene name synonym)|uniprotkb:Lipocortin VI(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:p70(gene name synonym)|uniprotkb:Protein III(gene name synonym)|uniprotkb:Chromobindin-20(gene name synonym)|uniprotkb:67 kDa calelectrin(gene name synonym)|uniprotkb:Calphobindin-II(gene name synonym)	psi-mi:q5nft7_fratt(display_long)|uniprotkb:pilB(gene name)|psi-mi:pilB(display_short)|uniprotkb:FTT_1133(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808944|imex:IM-13779-1316	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001146.2|refseq:NP_001180473.1|ensembl:ENSG00000197043.15(gene)|ensembl:ENST00000354546.10(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006937""(regulation of muscle contraction)|go:""GO:0008289""(lipid binding)|go:""GO:0012506""(vesicle membrane)|go:""GO:0015276""(ligand-gated monoatomic ion channel activity)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051283""(negative regulation of sequestering of calcium ion)|go:""GO:0051560""(mitochondrial calcium ion homeostasis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097190""(apoptotic signaling pathway)|interpro:IPR001464(Annexin)|interpro:IPR002393(Annexin, type VI)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08133|rcsb pdb:1M9I|reactome:R-HSA-445355|panther:PTHR10502(orthology-group)"	"interpro:IPR013374(Pilus assembly typeIV ATPase, PilB)|interpro:IPR007831(General secretory system II, protein E, N-terminal)|interpro:IPR001482(Type II secretion system protein E)|refseq:YP_170105.1|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_003021324.1|interpro:IPR037257"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+1oKdgl2a0haedrMSJ8au35MF8c9606	rogid:w3qerlfCYDBQclj/7Siavr6bjoQ177416	intact-crc:1DC26260EB84474C|rigid:Ng7lHD2jOPXmJZOeOWgCu0CfS9w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6UB99	uniprotkb:Q5NFN3	intact:EBI-2808987|uniprotkb:Q6QMF8|uniprotkb:Q6NTG1|ensembl:ENSP00000301030.4|ensembl:ENSP00000367581.2|ensembl:ENSP00000495226.1|intact:EBI-28972094	intact:EBI-2799271|uniprotkb:A0A0G2RMM7	psi-mi:anr11_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short)|uniprotkb:ANCO1(gene name synonym)|uniprotkb:Ankyrin repeat-containing cofactor 1(gene name synonym)	psi-mi:q5nfn3_fratt(display_long)|uniprotkb:sbcB(gene name)|psi-mi:sbcB(display_short)|uniprotkb:FTT_1200c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809002|imex:IM-13779-1322	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000167522.18(gene)|ensembl:ENST00000301030.10(transcript)|ensembl:ENST00000378330.7(transcript)|ensembl:ENST00000642600.2(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0060325""(face morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR042636|refseq:NP_001243111.1|refseq:NP_001243112.1|refseq:NP_037407.4|refseq:XP_011521353.1|refseq:XP_011521355.1|refseq:XP_016878671.1|refseq:XP_016878672.1|refseq:XP_016878673.1|refseq:XP_016878674.1|refseq:XP_016878675.1|refseq:XP_016878676.1|efo:""Orphanet:2332""|efo:""Orphanet:261250""|panther:PTHR24149(orthology-group)"	"interpro:IPR023607|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:YP_170159.1|interpro:IPR034747|interpro:IPR034748|go:""GO:0003677""(DNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0008310""(single-stranded DNA 3'-5' DNA exonuclease activity)|go:""GO:0045004""(DNA replication proofreading)|go:""GO:0046872""(metal ion binding)|refseq:WP_003021452.1|interpro:IPR013620(Exonuclease C-terminal)|interpro:IPR036397"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Pf1MnOge8bLsMtwuzGAmCsuXFcA9606	rogid:mZbdpZ1MtY92QBknO89wpvreVGg177416	intact-crc:B65A86B9BB67E999|rigid:mytAxoJi6rRWGq1lEO1iMiviHu4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60678	uniprotkb:Q5NFB0	intact:EBI-2809009|uniprotkb:B4DUC7|ensembl:ENSP00000331879.6|uniprotkb:A0A0A0MSN7	intact:EBI-2796314	psi-mi:anm3_human(display_long)|uniprotkb:PRMT3(gene name)|psi-mi:PRMT3(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3(gene name synonym)	"psi-mi:sys_fratt(display_long)|uniprotkb:""Seryl-tRNA(Ser/Sec) synthetase""(gene name synonym)|uniprotkb:FTT_1330(locus name)|uniprotkb:serS(gene name)|psi-mi:serS(display_short)|uniprotkb:Seryl-tRNA synthetase(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809013|imex:IM-13779-1324	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005779.1|ensembl:ENSG00000185238.13(gene)|ensembl:ENST00000331079.11(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0016274""(protein-arginine N-methyltransferase activity)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0032259""(methylation)|go:""GO:0035241""(protein-arginine omega-N monomethyltransferase activity)|go:""GO:0035242""(protein-arginine omega-N asymmetric methyltransferase activity)|go:""GO:0042054""(histone methyltransferase activity)|go:""GO:0043022""(ribosome binding)|go:""GO:0046872""(metal ion binding)|go:""GO:1900053""(negative regulation of retinoic acid biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036236|interpro:IPR049009|interpro:IPR049482|interpro:IPR055135|mint:O60678|rcsb pdb:2FYT|rcsb pdb:3SMQ|rcsb pdb:4HSG|rcsb pdb:4QQN|rcsb pdb:4RYL|rcsb pdb:8G2F|rcsb pdb:8G2G|rcsb pdb:8SHB|rcsb pdb:8SHR|rcsb pdb:8SIO|reactome:R-HSA-3214858|reactome:R-HSA-8876725|panther:PTHR11006(orthology-group)"	"go:""GO:0004828""(serine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006434""(seryl-tRNA aminoacylation)|go:""GO:0016260""(selenocysteine biosynthetic process)|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR010978(tRNA-binding arm)|refseq:YP_170282.1|refseq:WP_003022075.1|interpro:IPR033729|interpro:IPR045864|interpro:IPR042103"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XtFHON3qMCvjDhtN8RpXJo9KODU9606	rogid:M1krNL4X5Flp/80mQlBn60oe9eI177416	intact-crc:6ED937B5BE6F501F|rigid:DCtE+D0YmDesaI5uMIUWfUMxvY4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI74	uniprotkb:Q6UB98	intact:EBI-2797356|uniprotkb:A0A0G2RNT1	intact:EBI-2690224|uniprotkb:Q658K1|uniprotkb:Q6QMF7|uniprotkb:Q9H784|uniprotkb:O94951|uniprotkb:Q9H231|ensembl:ENSP00000262126.3	psi-mi:q5ni74_fratt(display_long)|uniprotkb:FTT_0209c(locus name)	psi-mi:anr12_human(display_long)|uniprotkb:ANCO2(gene name synonym)|uniprotkb:KIAA0874(gene name synonym)|uniprotkb:Ankyrin repeat-containing cofactor 2(gene name synonym)|uniprotkb:GAC-1 protein(gene name synonym)|uniprotkb:ANKRD12(gene name)|psi-mi:ANKRD12(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808980|imex:IM-13779-1321	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0007155""(cell adhesion)|go:""GO:0030001""(metal ion transport)|go:""GO:0046872""(metal ion binding)|interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006129(Adhesin B)|refseq:YP_169268.1|refseq:WP_003017523.1|interpro:IPR050492"	"refseq:XP_016881152.1|refseq:NP_001077094.1|refseq:NP_001190985.1|refseq:NP_056023.3|refseq:XP_005258149.1|refseq:XP_005258150.1|ensembl:ENSG00000101745.17(gene)|ensembl:ENST00000262126.9(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR053210|panther:PTHR24149(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SNzKG6SXy0yUlUpZyU9sv3eNyRk177416	rogid:etb60/sLQAg6in0go8JlQEGA9Os9606	intact-crc:8577BC955ED465A0|rigid:IvpSNBxL7RMI7LsFQTQlKrNkc6o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6UB99	uniprotkb:Q5NGE6	intact:EBI-2808987|uniprotkb:Q6QMF8|uniprotkb:Q6NTG1|ensembl:ENSP00000301030.4|ensembl:ENSP00000367581.2|ensembl:ENSP00000495226.1|intact:EBI-28972094	intact:EBI-2796264|uniprotkb:A0A0G2RNI3	psi-mi:anr11_human(display_long)|uniprotkb:ANKRD11(gene name)|psi-mi:ANKRD11(display_short)|uniprotkb:ANCO1(gene name synonym)|uniprotkb:Ankyrin repeat-containing cofactor 1(gene name synonym)	psi-mi:q5nge6_fratt(display_long)|uniprotkb:prlC(gene name)|psi-mi:prlC(display_short)|uniprotkb:FTT_0899c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2808995|imex:IM-13779-1323	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000167522.18(gene)|ensembl:ENST00000301030.10(transcript)|ensembl:ENST00000378330.7(transcript)|ensembl:ENST00000642600.2(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0060325""(face morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR042636|refseq:NP_001243111.1|refseq:NP_001243112.1|refseq:NP_037407.4|refseq:XP_011521353.1|refseq:XP_011521355.1|refseq:XP_016878671.1|refseq:XP_016878672.1|refseq:XP_016878673.1|refseq:XP_016878674.1|refseq:XP_016878675.1|refseq:XP_016878676.1|efo:""Orphanet:2332""|efo:""Orphanet:261250""|panther:PTHR24149(orthology-group)"	"go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|refseq:YP_169896.1|interpro:IPR024079|refseq:WP_003020904.1|interpro:IPR024077|interpro:IPR045090|interpro:IPR045666|interpro:IPR034005"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Pf1MnOge8bLsMtwuzGAmCsuXFcA9606	rogid:iZq1PA9Cyrdilxgx1L5ibpr8DmY177416	intact-crc:BF9CF7B9BA4AE9A3|rigid:vRCuj/eTr+MNN3hjkaLp5nNLxUo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P12235	uniprotkb:Q5NFY6	intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456.5	intact:EBI-2799813|uniprotkb:A0A0G2RNE0	psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym)	psi-mi:q5nfy6_fratt(display_long)|uniprotkb:FTT_1077c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809020|imex:IM-13779-1320	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR45635(orthology-group)|efo:""Orphanet:254892""|efo:""Orphanet:1369""|ensembl:ENSG00000151729.11(gene)|ensembl:ENST00000281456.11(transcript)|go:""GO:0000002""(mitochondrial genome maintenance)|go:""GO:0005471""(""ATP:ADP antiporter activity"")|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005757""(mitochondrial permeability transition pore complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0008637""(apoptotic mitochondrial changes)|go:""GO:0015078""(proton transmembrane transporter activity)|go:""GO:0015207""(adenine transmembrane transporter activity)|go:""GO:0015866""(ADP transport)|go:""GO:0016020""(membrane)|go:""GO:0017077""(oxidative phosphorylation uncoupler activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0046902""(regulation of mitochondrial membrane permeability)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0140021""(mitochondrial ADP transmembrane transport)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1901526""(positive regulation of mitophagy)|go:""GO:1990544""(mitochondrial ATP transmembrane transport)|go:""GO:1990845""(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-166187|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001142.2|dip:DIP-33116N"	refseq:WP_003021210.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606	rogid:LFa3hl2ASh3pWFeN78bCXUlWpKo177416	intact-crc:0D61E06B558E4E7D|rigid:3HwjF4hIVqbFINNRh8ttHC14Xes	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:Q07075	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-2809053|uniprotkb:Q504U2|ensembl:ENSP00000265162.5	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:ampe_human(display_long)|uniprotkb:ENPEP(gene name)|psi-mi:ENPEP(display_short)|uniprotkb:Aminopeptidase A(gene name synonym)|uniprotkb:Differentiation antigen gp160(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809058|imex:IM-13779-1325	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"refseq:NP_001968.3|ensembl:ENSG00000138792.10(gene)|ensembl:ENST00000265162.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0002003""(angiotensin maturation)|go:""GO:0003081""(regulation of systemic arterial blood pressure by renin-angiotensin)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0006508""(proteolysis)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032835""(glomerulus development)|go:""GO:0042277""(peptide binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0045177""(apical part of cell)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|interpro:IPR045357|interpro:IPR050344|rcsb pdb:4KX7|rcsb pdb:4KX8|rcsb pdb:4KX9|rcsb pdb:4KXA|rcsb pdb:4KXB|rcsb pdb:4KXC|rcsb pdb:4KXD|reactome:R-HSA-2022377|panther:PTHR11533(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:lYQrkjB4SD6xn+3ve6Gm/1HRU9s9606	intact-crc:911B4E859F11E982|rigid:ZqUAc+kvA5AEa7c6h/0jvUHqDYo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZTN6	uniprotkb:Q5NGZ2	intact:EBI-947028|uniprotkb:Q0VAK0|uniprotkb:Q6ZVD0|uniprotkb:Q86SU1|uniprotkb:D6RCN6|uniprotkb:Q0VGC3|ensembl:ENSP00000427130.2	intact:EBI-2799396	psi-mi:an13d_human(display_long)|uniprotkb:ANKRD13D(gene name)|psi-mi:ANKRD13D(display_short)	"psi-mi:q5ngz2_fratt(display_long)|uniprotkb:sthA(gene name)|psi-mi:sthA(display_short)|uniprotkb:""NAD(P)(+) transhydrogenase [B-specific]""(gene name synonym)|uniprotkb:FTT_0684c(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809034|imex:IM-13779-1326	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_997237.2|refseq:NP_001334830.1|ensembl:ENSG00000172932.16(gene)|ensembl:ENST00000511455.7(transcript)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0005737""(cytoplasm)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0140036""(ubiquitin-modified protein reader activity)|interpro:IPR002110(Ankyrin)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR021832|interpro:IPR036770|interpro:IPR055285|rcsb pdb:7RMA|panther:PTHR12447(orthology-group)"	"interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|refseq:YP_169700.1|go:""GO:0003957""(""NAD(P)+ transhydrogenase (Si-specific) activity"")|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR036188|interpro:IPR050151"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PnNGSoPIrih0F3fUD5AikA6Z5P89606	rogid:FVMwWTRsRhqkp8VA6v1GvkbWerE177416	intact-crc:A6084F9497E33FC0|rigid:3nmylC/ptlKy9zDyejzH4Dfofh8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHN5	uniprotkb:P15144	intact:EBI-2809041|uniprotkb:A0A0G2RQ25	intact:EBI-2563898|uniprotkb:Q16728|uniprotkb:Q9UCE0|uniprotkb:Q8IVH3|uniprotkb:Q8IUK3|uniprotkb:Q6GT90|ensembl:ENSP00000300060.6|ensembl:ENSP00000452934.2|ensembl:ENSP00000453413.2|ensembl:ENSP00000502886.1	psi-mi:q5nhn5_fratt(display_long)|uniprotkb:pulB(gene name)|psi-mi:pulB(display_short)|uniprotkb:FTT_0412c(locus name)	psi-mi:ampn_human(display_long)|uniprotkb:APN(gene name synonym)|uniprotkb:CD13(gene name synonym)|uniprotkb:PEPN(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:gp150(gene name synonym)|uniprotkb:Myeloid plasma membrane glycoprotein CD13(gene name synonym)|uniprotkb:ANPEP(gene name)|psi-mi:ANPEP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809046|imex:IM-13779-1328	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR011840(Pullulanase, type I)|refseq:YP_169457.1|interpro:IPR049117|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0051060""(pullulanase activity)|refseq:WP_003020143.1|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)"	"refseq:NP_001141.2|refseq:XP_011519775.1|ensembl:ENSG00000166825.15(gene)|ensembl:ENST00000300060.7(transcript)|ensembl:ENST00000559874.2(transcript)|ensembl:ENST00000560137.2(transcript)|ensembl:ENST00000679248.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042277""(peptide binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|interpro:IPR045357|interpro:IPR050344|mint:P15144|rcsb pdb:4FYQ|rcsb pdb:4FYR|rcsb pdb:4FYS|rcsb pdb:4FYT|rcsb pdb:5LHD|rcsb pdb:6ATK|rcsb pdb:6U7E|rcsb pdb:6U7F|rcsb pdb:6U7G|rcsb pdb:6XWD|rcsb pdb:7AEW|rcsb pdb:7VPQ|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:XP_005254949.1|panther:PTHR11533(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jdwFcN9LrSl0U8vcNPhHLwwhlJE177416	rogid:rKOeK87j6V1zOyRYGR7v2CHuZn09606	intact-crc:41FF962198049FF6|rigid:Aa7iN2iOc/7Sh7Zw7dh/HbmBh2c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV3	uniprotkb:Q9BTT0	intact:EBI-2797317	intact:EBI-2685059|uniprotkb:Q5TB18|uniprotkb:Q8N1S4|uniprotkb:Q8WWW9|uniprotkb:B4E0I6|uniprotkb:E9PEA6|uniprotkb:Q5TB20|ensembl:ENSP00000463154.1	psi-mi:q5ngv3_fratt(display_long)|uniprotkb:FTT_0726c(locus name)	psi-mi:an32e_human(display_long)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:ANP32E(gene name)|psi-mi:ANP32E(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809027|imex:IM-13779-1327	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0006629""(lipid metabolic process)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|interpro:IPR017946|refseq:YP_169739.1|interpro:IPR030395|refseq:WP_003020543.1"	"refseq:NP_001129950.1|refseq:NP_001129951.1|refseq:NP_112182.1|refseq:NP_001267488.1|refseq:NP_001267489.1|ensembl:ENSG00000143401.15(gene)|ensembl:ENST00000583931.6(transcript)|go:""GO:0000812""(Swr1 complex)|go:""GO:0005634""(nucleus)|go:""GO:0006325""(chromatin organization)|go:""GO:0019212""(phosphatase inhibitor activity)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0042393""(histone binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098895""(postsynaptic endosome membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140713""(histone chaperone activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR045081|mint:Q9BTT0|rcsb pdb:4CAY|rcsb pdb:4NFT|panther:PTHR11375(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3e+5yrpF/Mx2IYeXH2egqOFVYbs177416	rogid:byeFwwxqINXwewx0Gx/QXSyes8g9606	intact-crc:464C4BF51BD6F554|rigid:dIC78DUf5vGEyv+MSrrsNFFok24	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P05062	uniprotkb:Q5NHD1	intact:EBI-1045507|uniprotkb:Q5T7D6|uniprotkb:Q13741|uniprotkb:Q13742|ensembl:ENSP00000497731.1|ensembl:ENSP00000497767.1|ensembl:ENSP00000497990.1	intact:EBI-2799605|uniprotkb:A0A0G2RPC0	psi-mi:aldob_human(display_long)|uniprotkb:ALDOB(gene name)|psi-mi:ALDOB(display_short)|uniprotkb:ALDB(gene name synonym)|uniprotkb:Liver-type aldolase(gene name synonym)	psi-mi:q5nhd1_fratt(display_long)|uniprotkb:grxC(gene name)|psi-mi:grxC(display_short)|uniprotkb:FTT_0532c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809079|imex:IM-13779-1332	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:469""|ensembl:ENSG00000136872.21(gene)|ensembl:ENST00000647789.2(transcript)|ensembl:ENST00000648064.1(transcript)|ensembl:ENST00000648758.1(transcript)|go:""GO:0004332""(fructose-bisphosphate aldolase activity)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0006000""(fructose metabolic process)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0006116""(obsolete NADH oxidation)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0030388""(fructose 1,6-bisphosphate metabolic process)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042802""(identical protein binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061609""(fructose-1-phosphate aldolase activity)|go:""GO:0061624""(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate)|go:""GO:0070061""(fructose binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070072""(vacuolar proton-transporting V-type ATPase complex assembly)|go:""GO:1905856""(negative regulation of pentose-phosphate shunt)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P05062|rcsb pdb:1QO5|rcsb pdb:1XDL|rcsb pdb:1XDM|rcsb pdb:8D44|reactome:R-HSA-5657560|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-70350|refseq:NP_000026.2|panther:PTHR11627(orthology-group)"	"interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR002109(Glutaredoxin)|interpro:IPR014025(Glutaredoxin subgroup)|interpro:IPR000358(Ribonucleotide reductase)|refseq:YP_169561.1|go:""GO:0004748""(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:""GO:0009263""(deoxyribonucleotide biosynthetic process)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_003023235.1|interpro:IPR036249|interpro:IPR011900(Glutaredoxin, GrxC)|interpro:IPR033909|interpro:IPR012348(Ribonucleotide reductase-related)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Bio5Ywd/bEDrDUsJ3DsO1IEhE3M9606	rogid:Zlpot7hmLVzAffGINLtgVgDpcoA177416	intact-crc:FFFC4E343C1EF242|rigid:NecY7mJ+fPEgWmTs7Hflv9aVGQ4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFY6	uniprotkb:P04075	intact:EBI-2799813|uniprotkb:A0A0G2RNE0	intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452.2|ensembl:ENSP00000455700.1|ensembl:ENSP00000455800.2|ensembl:ENSP00000494188.2	psi-mi:q5nfy6_fratt(display_long)|uniprotkb:FTT_1077c(locus name)	psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809086|imex:IM-13779-1330	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003021210.1	"efo:""Orphanet:57""|ensembl:ENSG00000149925.22(gene)|ensembl:ENST00000412304.6(transcript)|ensembl:ENST00000563060.6(transcript)|ensembl:ENST00000569545.5(transcript)|ensembl:ENST00000643777.4(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0004332""(fructose-bisphosphate aldolase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006000""(fructose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0006941""(striated muscle contraction)|go:""GO:0007015""(actin filament organization)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0015631""(tubulin binding)|go:""GO:0016020""(membrane)|go:""GO:0030388""(fructose 1,6-bisphosphate metabolic process)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031430""(M band)|go:""GO:0031674""(I band)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0061827""(sperm head)|go:""GO:0070061""(fructose binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|rcsb pdb:6XMH|rcsb pdb:6XML|rcsb pdb:6XMM|rcsb pdb:6XMO|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263|refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|panther:PTHR11627(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:LFa3hl2ASh3pWFeN78bCXUlWpKo177416	rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606	intact-crc:6531B9A0EF08A4CC|rigid:a/d5heFfIM+ULzRFOhJbqAJaPSw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIJ3	uniprotkb:P05062	intact:EBI-2798422|uniprotkb:A0A0G2RM06	intact:EBI-1045507|uniprotkb:Q5T7D6|uniprotkb:Q13741|uniprotkb:Q13742|ensembl:ENSP00000497731.1|ensembl:ENSP00000497767.1|ensembl:ENSP00000497990.1	psi-mi:q5nij3_fratt(display_long)|uniprotkb:sdhA(gene name)|psi-mi:sdhA(display_short)|uniprotkb:FTT_0074(locus name)	psi-mi:aldob_human(display_long)|uniprotkb:ALDOB(gene name)|psi-mi:ALDOB(display_short)|uniprotkb:ALDB(gene name synonym)|uniprotkb:Liver-type aldolase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809072|imex:IM-13779-1329	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0008177""(""succinate dehydrogenase (quinone) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0009061""(anaerobic respiration)|go:""GO:0022900""(electron transport chain)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|refseq:YP_169149.1|interpro:IPR027477|refseq:WP_003019788.1|interpro:IPR036188|interpro:IPR037099|interpro:IPR030664"	"efo:""Orphanet:469""|ensembl:ENSG00000136872.21(gene)|ensembl:ENST00000647789.2(transcript)|ensembl:ENST00000648064.1(transcript)|ensembl:ENST00000648758.1(transcript)|go:""GO:0004332""(fructose-bisphosphate aldolase activity)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0006000""(fructose metabolic process)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0006116""(obsolete NADH oxidation)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0030388""(fructose 1,6-bisphosphate metabolic process)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042802""(identical protein binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061609""(fructose-1-phosphate aldolase activity)|go:""GO:0061624""(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate)|go:""GO:0070061""(fructose binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070072""(vacuolar proton-transporting V-type ATPase complex assembly)|go:""GO:1905856""(negative regulation of pentose-phosphate shunt)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P05062|rcsb pdb:1QO5|rcsb pdb:1XDL|rcsb pdb:1XDM|rcsb pdb:8D44|reactome:R-HSA-5657560|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-70350|refseq:NP_000026.2|panther:PTHR11627(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sDR33MuGlwHfY9HuZdMhwuYSZI8177416	rogid:Bio5Ywd/bEDrDUsJ3DsO1IEhE3M9606	intact-crc:498F3F343CA42114|rigid:sSlzgR38Gv+Ltaq2SP1WgnxmDnQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFB0	uniprotkb:P05062	intact:EBI-2796314	intact:EBI-1045507|uniprotkb:Q5T7D6|uniprotkb:Q13741|uniprotkb:Q13742|ensembl:ENSP00000497731.1|ensembl:ENSP00000497767.1|ensembl:ENSP00000497990.1	"psi-mi:sys_fratt(display_long)|uniprotkb:""Seryl-tRNA(Ser/Sec) synthetase""(gene name synonym)|uniprotkb:FTT_1330(locus name)|uniprotkb:serS(gene name)|psi-mi:serS(display_short)|uniprotkb:Seryl-tRNA synthetase(gene name synonym)"	psi-mi:aldob_human(display_long)|uniprotkb:ALDOB(gene name)|psi-mi:ALDOB(display_short)|uniprotkb:ALDB(gene name synonym)|uniprotkb:Liver-type aldolase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809065|imex:IM-13779-1331	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004828""(serine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006434""(seryl-tRNA aminoacylation)|go:""GO:0016260""(selenocysteine biosynthetic process)|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR010978(tRNA-binding arm)|refseq:YP_170282.1|refseq:WP_003022075.1|interpro:IPR033729|interpro:IPR045864|interpro:IPR042103"	"efo:""Orphanet:469""|ensembl:ENSG00000136872.21(gene)|ensembl:ENST00000647789.2(transcript)|ensembl:ENST00000648064.1(transcript)|ensembl:ENST00000648758.1(transcript)|go:""GO:0004332""(fructose-bisphosphate aldolase activity)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0006000""(fructose metabolic process)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0006116""(obsolete NADH oxidation)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0030388""(fructose 1,6-bisphosphate metabolic process)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042802""(identical protein binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061609""(fructose-1-phosphate aldolase activity)|go:""GO:0061624""(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate)|go:""GO:0070061""(fructose binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070072""(vacuolar proton-transporting V-type ATPase complex assembly)|go:""GO:1905856""(negative regulation of pentose-phosphate shunt)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P05062|rcsb pdb:1QO5|rcsb pdb:1XDL|rcsb pdb:1XDM|rcsb pdb:8D44|reactome:R-HSA-5657560|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-70350|refseq:NP_000026.2|panther:PTHR11627(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M1krNL4X5Flp/80mQlBn60oe9eI177416	rogid:Bio5Ywd/bEDrDUsJ3DsO1IEhE3M9606	intact-crc:35FEE0343C43C415|rigid:4pph0igTLcC36mcqgevRVP8DtQ8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFY4	uniprotkb:Q6ZS30	intact:EBI-2799645|uniprotkb:A0A0G2RQ80	intact:EBI-2809093|uniprotkb:Q8N8R4|uniprotkb:Q96Q31|uniprotkb:Q6Y876|uniprotkb:Q6ZQY5|uniprotkb:Q96Q30|uniprotkb:A6NHD5|intact:EBI-2863604|uniprotkb:Q6ZP36|ensembl:ENSP00000399903.1	psi-mi:q5nfy4_fratt(display_long)|uniprotkb:FTT_1079c(locus name)	psi-mi:nbel1_human(display_long)|uniprotkb:NBEAL1(gene name)|psi-mi:NBEAL1(display_short)|uniprotkb:ALS2CR16(gene name synonym)|uniprotkb:ALS2CR17(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809113|imex:IM-13779-1334	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_170058.1|refseq:WP_003026641.1	"refseq:NP_001107604.1|ensembl:ENSG00000144426.19(gene)|ensembl:ENST00000449802.5(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|interpro:IPR046851|interpro:IPR050865|panther:PTHR13743(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v1mSgBDe90RxW8uHIi9a67zCxJs177416	rogid:WVn2v6T+2goH2bDo+010vjmzk049606	intact-crc:E01EFE0514173E71|rigid:rQDCuUzjPorUqLhbDqBRx+jw49U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGF1	uniprotkb:Q8N187	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	intact:EBI-745541|uniprotkb:Q8ND29|uniprotkb:Q8WXC0|uniprotkb:Q96J78|uniprotkb:Q96Q38|uniprotkb:Q96Q39|uniprotkb:Q9H712|uniprotkb:B4E1W7|uniprotkb:G3V1K7|ensembl:ENSP00000384006.2|ensembl:ENSP00000414644.1	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	psi-mi:cartf_human(display_long)|uniprotkb:CARF(gene name)|psi-mi:CARF(display_short)|uniprotkb:ALS2CR8(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein(gene name synonym)|uniprotkb:Calcium-response factor(gene name synonym)|uniprotkb:Testis development protein NYD-SP24(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809120|imex:IM-13779-1336	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"refseq:NP_001269840.1|refseq:NP_001098056.1|refseq:NP_079020.13|refseq:XP_005246915.1|refseq:XP_005246916.1|refseq:NP_001309356.1|refseq:NP_001309357.1|refseq:NP_001269839.1|refseq:XP_011510169.1|refseq:XP_016860450.1|ensembl:ENSG00000138380.18(gene)|ensembl:ENST00000402905.7(transcript)|ensembl:ENST00000438828.4(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001652""(granular component)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0071277""(cellular response to calcium ion)|interpro:IPR029309|panther:PTHR14694(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	rogid:EiUNZRG00WzGQHUAO64MtIPt4ow9606	intact-crc:89BF233B653DFFE8|rigid:NXjaOrB5lRLISvzVHRVi8ePGLf0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFD5	uniprotkb:P00352	intact:EBI-2797949|uniprotkb:A0A0G2RLZ8	intact:EBI-752170|ensembl:ENSP00000297785.3|uniprotkb:O00768|uniprotkb:Q5SYR1	psi-mi:q5nfd5_fratt(display_long)|uniprotkb:FTT_1303c(locus name)	psi-mi:al1a1_human(display_long)|uniprotkb:Aldehyde dehydrogenase family 1 member A1(gene name synonym)|uniprotkb:Aldehyde dehydrogenase, cytosolic(gene name synonym)|uniprotkb:ALHDII(gene name synonym)|uniprotkb:ALDH-E1(gene name synonym)|uniprotkb:ALDH1A1(gene name)|psi-mi:ALDH1A1(display_short)|uniprotkb:ALDC(gene name synonym)|uniprotkb:ALDH1(gene name synonym)|uniprotkb:PUMB1(gene name synonym)|uniprotkb:3-deoxyglucosone dehydrogenase(gene name synonym)|uniprotkb:Retinal dehydrogenase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809127|imex:IM-13779-1333	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_170257.1|refseq:WP_003022016.1	"ensembl:ENSG00000165092.13(gene)|ensembl:ENST00000297785.8(transcript)|go:""GO:0001523""(retinoid metabolic process)|go:""GO:0001758""(retinal dehydrogenase activity)|go:""GO:0004029""(""aldehyde dehydrogenase (NAD+) activity"")|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005497""(androgen binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006081""(aldehyde metabolic process)|go:""GO:0009449""(gamma-aminobutyric acid biosynthetic process)|go:""GO:0018479""(""benzaldehyde dehydrogenase (NAD+) activity"")|go:""GO:0019145""(""aminobutyraldehyde dehydrogenase (NAD+) activity"")|go:""GO:0030392""(fructosamine catabolic process)|go:""GO:0030424""(axon)|go:""GO:0036438""(maintenance of lens transparency)|go:""GO:0042572""(retinol metabolic process)|go:""GO:0045202""(synapse)|go:""GO:0051287""(NAD binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106373""(3-deoxyglucosone dehydrogenase activity)|go:""GO:0110095""(cellular detoxification of aldehyde)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|rcsb pdb:4WB9|rcsb pdb:4WJ9|rcsb pdb:4WP7|rcsb pdb:4WPN|rcsb pdb:4X4L|rcsb pdb:5AC2|rcsb pdb:5L2M|rcsb pdb:5L2N|rcsb pdb:5L2O|rcsb pdb:5TEI|rcsb pdb:6DUM|rcsb pdb:7JWS|rcsb pdb:7JWT|rcsb pdb:7JWU|rcsb pdb:7JWV|rcsb pdb:7JWW|rcsb pdb:7UM9|rcsb pdb:8D46|rcsb pdb:8DNO|rcsb pdb:8ENE|rcsb pdb:8PVH|rcsb pdb:8T0N|rcsb pdb:8T0T|rcsb pdb:8WFQ|reactome:R-HSA-5365859|reactome:R-HSA-70350|reactome:R-HSA-71384|refseq:NP_000680.2|panther:PTHR11699(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:03iWKOdUn+kzeDSd3dWBRWkfQoY177416	rogid:59BsLsRErg8L8BRi/1Wp6ahycX09606	intact-crc:D29AC6BE65B364E3|rigid:S1k6cdPjymdNZ/pvRhnhJPsjAhU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZS30	uniprotkb:Q5NH38	intact:EBI-2809093|uniprotkb:Q8N8R4|uniprotkb:Q96Q31|uniprotkb:Q6Y876|uniprotkb:Q6ZQY5|uniprotkb:Q96Q30|uniprotkb:A6NHD5|intact:EBI-2863604|uniprotkb:Q6ZP36|ensembl:ENSP00000399903.1	intact:EBI-2797227|uniprotkb:A0A0G2RP54	psi-mi:nbel1_human(display_long)|uniprotkb:NBEAL1(gene name)|psi-mi:NBEAL1(display_short)|uniprotkb:ALS2CR16(gene name synonym)|uniprotkb:ALS2CR17(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein(gene name synonym)	psi-mi:q5nh38_fratt(display_long)|uniprotkb:hflK(gene name)|psi-mi:hflK(display_short)|uniprotkb:FTT_0633(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809106|imex:IM-13779-1335	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001107604.1|ensembl:ENSG00000144426.19(gene)|ensembl:ENST00000449802.5(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|interpro:IPR046851|interpro:IPR050865|panther:PTHR13743(orthology-group)"	"go:""GO:0016020""(membrane)|interpro:IPR001107(Band 7 protein)|interpro:IPR010201(HflK)|refseq:YP_169654.1|refseq:WP_003023444.1|interpro:IPR036013|interpro:IPR050710"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WVn2v6T+2goH2bDo+010vjmzk049606	rogid:0bj8rSZ7SoJuK6iGQz/clayaUPs177416	intact-crc:4510500517965AA9|rigid:f+bwiv0f9LNW8srjBbVegiYIK1I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12802	uniprotkb:Q5NFN4	intact:EBI-1373806|uniprotkb:Q14572|uniprotkb:Q59FP6|uniprotkb:Q86W90|uniprotkb:Q8WXQ6|uniprotkb:Q96JP6|uniprotkb:Q96P79|uniprotkb:Q9Y5T0|uniprotkb:Q9Y5T6|ensembl:ENSP00000378026.3|intact:EBI-28978093	intact:EBI-2796796	psi-mi:akp13_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 13(gene name synonym)|uniprotkb:Breast cancer nuclear receptor-binding auxiliary protein(gene name synonym)|uniprotkb:Human thyroid-anchoring protein 31(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor Lbc(gene name synonym)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:Lymphoid blast crisis oncogene(gene name synonym)|uniprotkb:Non-oncogenic Rho GTPase-specific GTP exchange factor(gene name synonym)|uniprotkb:AKAP13(gene name)|psi-mi:AKAP13(display_short)|uniprotkb:BRX(gene name synonym)|uniprotkb:HT31(gene name synonym)|uniprotkb:LBC(gene name synonym)	psi-mi:uvrb_fratt(display_long)|uniprotkb:Excinuclease ABC subunit B(gene name synonym)|uniprotkb:FTT_1199c(locus name)|uniprotkb:uvrB(gene name)|psi-mi:uvrB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809134|imex:IM-13779-1337	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006729.4|refseq:NP_009131.2|refseq:NP_001257475.1|ensembl:ENSG00000170776.22(gene)|ensembl:ENST00000394518.7(transcript)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007507""(heart development)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0046872""(metal ion binding)|go:""GO:0051018""(protein kinase A binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060297""(regulation of sarcomere organization)|go:""GO:0060348""(bone development)|go:""GO:0071875""(adrenergic receptor signaling pathway)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018459|interpro:IPR035899|interpro:IPR041020|interpro:IPR046349|interpro:IPR051632|mint:Q12802|rcsb pdb:2DRN|rcsb pdb:2LG1|rcsb pdb:4D0N|rcsb pdb:4D0O|rcsb pdb:6BCA|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|dip:DIP-180N|panther:PTHR13944(orthology-group)"	"go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170158.1|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004807(Excinuclease ABC, B subunit)|interpro:IPR024759|interpro:IPR027417|interpro:IPR036876|interpro:IPR041471|refseq:WP_003021449.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pHHpKUh10J/O/fp06k4NaNhJF6U9606	rogid:Jhq9KYkHYrpyhq5qkOrHkcqCWVk177416	intact-crc:D9C2551C5A16996F|rigid:fNSxLVyEEGRxK6rg/AeU4TrfD6I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08117	uniprotkb:Q5NH75	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	intact:EBI-2800607|uniprotkb:A0A0G2RNR2	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:q5nh75_fratt(display_long)|uniprotkb:FTT_0594c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809162|imex:IM-13779-1342	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"refseq:YP_169617.1|go:""GO:0019148""(D-cysteine desulfhydrase activity)|refseq:WP_003023336.1|interpro:IPR027278|interpro:IPR036052"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:ESQ/PSYWnwiTRAHK+vmXTjfZ3No177416	intact-crc:A58A593B7E97FC93|rigid:SLCCr+rIF65u2Ra5qHGEe986zQQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:Q7Z591	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-2799297|uniprotkb:Q64FX8|uniprotkb:Q64FY2|uniprotkb:Q96RR9|uniprotkb:Q05BK5|uniprotkb:Q6ZNL2|uniprotkb:Q5T535|uniprotkb:Q8TET1|uniprotkb:Q6ZTX0|uniprotkb:Q64FX7|uniprotkb:Q5T536|uniprotkb:Q5T537|uniprotkb:Q9H7P7|uniprotkb:Q64FX6|uniprotkb:Q6ZMK0|uniprotkb:Q8TF33|ensembl:ENSP00000303769.4|ensembl:ENSP00000363201.3|intact:EBI-28973907	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:akna_human(display_long)|uniprotkb:KIAA1968(gene name synonym)|uniprotkb:AKNA(gene name)|psi-mi:AKNA(display_short)|uniprotkb:AT-hook-containing transcription factor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809141|imex:IM-13779-1338	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"refseq:XP_011517365.1|refseq:NP_110394.3|ensembl:ENSG00000106948.17(gene)|ensembl:ENST00000307564.8(transcript)|ensembl:ENST00000374088.8(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0003677""(DNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0016020""(membrane)|go:""GO:0021849""(neuroblast division in subventricular zone)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0060232""(delamination)|go:""GO:0060234""(neuroblast delamination)|interpro:IPR022150|interpro:IPR052655|mint:Q7Z591|refseq:XP_006717357.1|refseq:XP_006717358.1|refseq:XP_005252301.1|refseq:XP_005252302.1|refseq:XP_005252304.1|refseq:XP_011517367.2|refseq:NP_001304879.1|refseq:NP_001304881.1|refseq:XP_016870661.1|panther:PTHR21510(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:1SOl7aUskaYwF6Qp7HzL57zx3Ok9606	intact-crc:1471CAE366378C46|rigid:DbCZ4rO/BVViMY61LyNJj5bma0Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08117	uniprotkb:Q5NEC0	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809169|imex:IM-13779-1340	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:FB5D643B7FAB7E13|rigid:YLF67eOF//tLbux42HdfOQ6PgaU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P51825	uniprotkb:Q5NEM9	intact:EBI-2610180|intact:EBI-28974592|ensembl:ENSP00000305689.6|uniprotkb:B4DTU1|uniprotkb:E9PBM3|intact:EBI-11028221	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:aff1_human(display_long)|uniprotkb:AFF1(gene name)|psi-mi:AFF1(display_short)|uniprotkb:AF4(gene name synonym)|uniprotkb:FEL(gene name synonym)|uniprotkb:MLLT2(gene name synonym)|uniprotkb:PBM1(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 4 protein(gene name synonym)|uniprotkb:Proto-oncogene AF4(gene name synonym)|uniprotkb:Protein FEL(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809155|imex:IM-13779-1339	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000172493.23(gene)|ensembl:ENST00000307808.10(transcript)|go:""GO:0008023""(transcription elongation factor complex)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0032783""(super elongation complex)|interpro:IPR007797(AF-4 proto-oncoprotein)|interpro:IPR043639|interpro:IPR043640|mint:P51825|rcsb pdb:2LM0|refseq:NP_001160165.1|refseq:NP_001300888.1|refseq:NP_001300889.1|refseq:NP_005926.1|refseq:XP_005263064.1|refseq:XP_011530275.1|dip:DIP-56407N|efo:""Orphanet:589595""|panther:PTHR10528(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/31	rogid:dfXWN9v1lQ9Tz77hzdYOBy7xn1Q9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:6B9229F54237D750|rigid:qQZ7Jt6p9u1cNoKnF7Xw+N9btDY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q09666	uniprotkb:Q5NII1	intact:EBI-2555881|uniprotkb:A1A586|ensembl:ENSP00000367263.4	intact:EBI-2797156|uniprotkb:A0A0G2RN00	psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short)	psi-mi:q5nii1_fratt(display_long)|uniprotkb:acnA(gene name)|psi-mi:acnA(display_short)|uniprotkb:FTT_0087(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809148|imex:IM-13779-1341	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001611.1|refseq:NP_076965.2|refseq:NP_001333374.1|refseq:NP_001333375.1|ensembl:ENSG00000124942.14(gene)|ensembl:ENST00000378024.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030315""(T-tubule)|go:""GO:0031982""(vesicle)|go:""GO:0042383""(sarcolemma)|go:""GO:0042802""(identical protein binding)|go:""GO:0043034""(costamere)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097493""(structural molecule activity conferring elasticity)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1901385""(regulation of voltage-gated calcium channel activity)|go:""GO:1905686""(positive regulation of plasma membrane repair)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR052082|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|panther:PTHR23348(orthology-group)"	"go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR044137|refseq:YP_169161.1|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR018136|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|refseq:WP_003019815.1|interpro:IPR036008"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:u1oecAyIihgxzfTz0jholE8wksA9606	rogid:FGVUBUKOHsDquKU0LqPkXCpRg+o177416	intact-crc:C06DC370AF10E6AF|rigid:S1fdyAliNtBvX317WP4ayBcPeDs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFK7	uniprotkb:Q7Z6V5	intact:EBI-2797846|uniprotkb:A0A0G2RN70	intact:EBI-2809203|uniprotkb:B3KWY3|uniprotkb:A6NL12|uniprotkb:Q7Z327|uniprotkb:Q8IY39|ensembl:ENSP00000237283.8	psi-mi:q5nfk7_fratt(display_long)|uniprotkb:rne(gene name)|psi-mi:rne(display_short)|uniprotkb:FTT_1227(locus name)	psi-mi:adat2_human(display_long)|uniprotkb:ADAT2(gene name)|psi-mi:ADAT2(display_short)|uniprotkb:DEADC1(gene name synonym)|uniprotkb:Deaminase domain-containing protein 1(gene name synonym)|uniprotkb:tRNA-specific adenosine-34 deaminase subunit ADAT2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809211|imex:IM-13779-1345	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006364""(rRNA processing)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008033""(tRNA processing)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008995""(ribonuclease E activity)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019843""(rRNA binding)|interpro:IPR028878|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR019307|interpro:IPR004659(Ribonuclease E and G)|refseq:YP_170185.1|refseq:WP_003021514.1|interpro:IPR048583"	"refseq:NP_001273188.1|refseq:NP_872309.2|refseq:XP_011533742.1|refseq:XP_011533746.1|ensembl:ENSG00000189007.16(gene)|ensembl:ENST00000237283.9(transcript)|go:""GO:0002100""(tRNA wobble adenosine to inosine editing)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0052717""(tRNA-specific adenosine-34 deaminase activity)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR028883|rcsb pdb:3DH1|reactome:R-HSA-6782315|refseq:XP_016865749.1|refseq:XP_016865750.1|refseq:XP_016865751.1|panther:PTHR11079(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:T1YeruV0gQXSr2JVi+sAPAQCsl0177416	rogid:mwylMotiNwPQkBT0PWBOGUgUjE49606	intact-crc:ECE70F5F21C56318|rigid:Df7TJf6FW7xjWXbgtf1qwj7hSEo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35611	uniprotkb:Q5NI40	intact:EBI-2809187|uniprotkb:Q16156|uniprotkb:Q14729|uniprotkb:A2A3P0|uniprotkb:Q13734|uniprotkb:Q9UJB6|uniprotkb:D3DVR3|uniprotkb:D3DVR4|uniprotkb:D3DVR5|uniprotkb:Q86XM2|ensembl:ENSP00000381197.1|uniprotkb:B4DI79|uniprotkb:A2A3N8|intact:EBI-28966889	intact:EBI-2796048	psi-mi:adda_human(display_long)|uniprotkb:ADD1(gene name)|psi-mi:ADD1(display_short)|uniprotkb:ADDA(gene name synonym)|uniprotkb:Erythrocyte adducin subunit alpha(gene name synonym)	psi-mi:q5ni40_fratt(display_long)|uniprotkb:ppdK(gene name)|psi-mi:ppdK(display_short)|uniprotkb:FTT_0250(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809196|imex:IM-13779-1343	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273574.1|refseq:XP_005247994.1|refseq:NP_001110.2|refseq:NP_054908.2|refseq:NP_054909.2|refseq:NP_789771.1|ensembl:ENSG00000087274.19(gene)|ensembl:ENST00000398129.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016604""(nuclear body)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030507""(spectrin binding)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:1903142""(positive regulation of establishment of endothelial barrier)|go:""GO:1903393""(positive regulation of adherens junction organization)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|interpro:IPR051017|mint:P35611|reactome:R-HSA-264870|reactome:R-HSA-381038|reactome:R-HSA-5223345|refseq:XP_016863193.1|refseq:XP_016863195.1|refseq:XP_016863196.1|refseq:XP_016863197.1|refseq:XP_016863198.1|refseq:XP_016863199.1|panther:PTHR10672(orthology-group)"	"refseq:YP_169302.1|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR018274|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR023151|interpro:IPR002192(Pyruvate phosphate dikinase, PEP/pyruvate-binding)|interpro:IPR010121(Pyruvate, phosphate dikinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR040442|interpro:IPR036637|go:""GO:0005524""(ATP binding)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0050242""(pyruvate, phosphate dikinase activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aXiCTFAzsmSxxV4OAr22SDyjAxI9606	rogid:lPu2TgwGa8adgnlyO6g7UzHr7Ns177416	intact-crc:971B7EF1068BAD69|rigid:M6JGD4Nc3eM+kAvMs0IzxY9fEA8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI31	uniprotkb:Q9H2P0	intact:EBI-2809179	intact:EBI-1764854|uniprotkb:E1P5Y2|uniprotkb:O94881|uniprotkb:Q5BKU2|uniprotkb:Q9UG34|intact:EBI-28975656|ensembl:ENSP00000342905.3|ensembl:ENSP00000360662.2|ensembl:ENSP00000379346.3|ensembl:ENSP00000379349.2|ensembl:ENSP00000483881.1	psi-mi:hem3_fratt(display_long)|uniprotkb:hemC(gene name)|psi-mi:hemC(display_short)|uniprotkb:Hydroxymethylbilane synthase(gene name synonym)|uniprotkb:Pre-uroporphyrinogen synthase(gene name synonym)|uniprotkb:FTT_0259(locus name)	psi-mi:adnp_human(display_long)|uniprotkb:ADNP(gene name)|psi-mi:ADNP(display_short)|uniprotkb:ADNP1(gene name synonym)|uniprotkb:KIAA0784(gene name synonym)|uniprotkb:Activity-dependent neuroprotective protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809176|imex:IM-13779-1344	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000860(Tetrapyrrole biosynthesis, hydroxymethylbilane synthase)|interpro:IPR022419|interpro:IPR022417|interpro:IPR022418|refseq:YP_169311.1|go:""GO:0004418""(hydroxymethylbilane synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|refseq:WP_003021732.1|interpro:IPR036803"	"dip:DIP-47288N|efo:""Orphanet:404448""|ensembl:ENSG00000101126.18(gene)|ensembl:ENST00000349014.8(transcript)|ensembl:ENST00000371602.9(transcript)|ensembl:ENST00000396029.8(transcript)|ensembl:ENST00000396032.8(transcript)|ensembl:ENST00000621696.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0005507""(copper ion binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007614""(short-term memory)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009743""(response to carbohydrate)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0033484""(intracellular nitric oxide homeostasis)|go:""GO:0042277""(peptide binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0044849""(estrous cycle)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050805""(negative regulation of synaptic transmission)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051965""(positive regulation of synapse assembly)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|interpro:IPR045762|mint:Q9H2P0|refseq:NP_001269460.1|refseq:NP_001269461.1|refseq:NP_001334440.1|refseq:NP_056154.1|refseq:NP_852107.1|refseq:XP_011527049.1|refseq:XP_016883247.1|refseq:XP_016883248.1|panther:PTHR15740(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BzgMFLTzatwTYT9v+QH37+kHU8E177416	rogid:QJTl6p2b0Lp7HnHP8sFd5Hv+WGk9606	intact-crc:B13D5B3F49D41778|rigid:8bTkhKQS+lGBPG1QWikTod9+dTE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NI89	uniprotkb:Q02548	intact:EBI-2796250	intact:EBI-296331|uniprotkb:A3QVP6|uniprotkb:A3QVP7|uniprotkb:A3QVP8|uniprotkb:O75933|intact:EBI-2809225|uniprotkb:Q5SFM2|uniprotkb:Q6S728|uniprotkb:Q6S729|uniprotkb:Q6S730|uniprotkb:Q6S731|uniprotkb:Q6S732|ensembl:ENSP00000350844.4|uniprotkb:C0KTF6|uniprotkb:C0KTF7|uniprotkb:C0KTF8|uniprotkb:C0KTF9|uniprotkb:C0KTG0	psi-mi:q5ni89_fratt(display_long)|uniprotkb:lysS(gene name synonym)|uniprotkb:lysU(gene name)|psi-mi:lysU(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_0192(locus name)	psi-mi:pax5_human(display_long)|uniprotkb:PAX5(gene name)|psi-mi:PAX5(display_short)|uniprotkb:B-cell-specific transcription factor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809229|imex:IM-13779-1348	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|interpro:IPR044136|refseq:YP_169253.1|interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR045864"	"efo:""Orphanet:641372""|ensembl:ENSG00000196092.14(gene)|ensembl:ENST00000358127.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007399""(nervous system development)|go:""GO:0007423""(sensory organ development)|go:""GO:0021670""(lateral ventricle development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030534""(adult behavior)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0048701""(embryonic cranial skeleton morphogenesis)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|rcsb pdb:1K78|rcsb pdb:1MDM|reactome:R-HSA-8939245|refseq:NP_001267476.1|refseq:NP_001267477.1|refseq:NP_001267478.1|refseq:NP_001267479.1|refseq:NP_001267481.1|refseq:NP_001267482.1|refseq:NP_001267483.1|refseq:NP_001267484.1|refseq:NP_001267485.1|refseq:NP_057953.1|ensembl:ENSP00000350844.4|ensembl:ENST00000377840.6|ensembl:ENSP00000367071.2|ensembl:ENST00000377847.6|ensembl:ENSP00000367078.2|ensembl:ENST00000377852.7|ensembl:ENSP00000367083.2|ensembl:ENST00000377853.6|ensembl:ENSP00000367084.2|ensembl:ENST00000414447.5|ensembl:ENSP00000412188.1|ensembl:ENST00000446742.5|ensembl:ENSP00000404687.1|ensembl:ENST00000520281.5|ensembl:ENSP00000430773.1|ensembl:ENST00000523493.5|ensembl:ENSP00000431038.1|panther:PTHR45636(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4e6LdrlEB4PMi+b0yLmkVagonC4177416	rogid:zq0Ew8GL7Svag27Dk2KlJ3OMEFs9606	intact-crc:B702774D9A4D85FD|rigid:Kj/4lg9LLHTbWeKWFjuP9Q/FICw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGV3	uniprotkb:A8K9Y5	intact:EBI-2797317	intact:EBI-2809249	psi-mi:q5ngv3_fratt(display_long)|uniprotkb:FTT_0726c(locus name)	psi-mi:a8k9y5_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809246|imex:IM-13779-1349	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0006629""(lipid metabolic process)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|interpro:IPR017946|refseq:YP_169739.1|interpro:IPR030395|refseq:WP_003020543.1"	"interpro:IPR049730|interpro:IPR023780|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000330(SNF2-related)|interpro:IPR038718|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016787""(hydrolase activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3e+5yrpF/Mx2IYeXH2egqOFVYbs177416	rogid:33GOqabqaL4Rbx4rktjcRfgP4zA9606	intact-crc:8AE64B6C08AC3141|rigid:lYMSYDVB1TNllF8c7ybS0cGjKNw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIP5	uniprotkb:A8KAD5	intact:EBI-2797625	intact:EBI-2809236	psi-mi:gatb_fratt(display_long)|uniprotkb:FTT_0021(locus name)|uniprotkb:gatB(gene name)|psi-mi:gatB(display_short)	psi-mi:a8kad5_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809239|imex:IM-13779-1347	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0050566""(""asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0070681""(glutaminyl-tRNAGln biosynthesis via transamidation)|interpro:IPR017959|interpro:IPR006075(GatB N-terminal region)|interpro:IPR018027|interpro:IPR003789(GatB/Yqey)|interpro:IPR023168|interpro:IPR004413(""Glutamyl-tRNA(Gln) amidotransferase B subunit"")|interpro:IPR017958|refseq:YP_169097.1|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|refseq:WP_003017411.1"	"interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|refseq:NP_001137535.1|go:""GO:0006869""(lipid transport)|go:""GO:0008289""(lipid binding)|interpro:IPR037239"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MULE4syC9yNG02pvDj3Le0UVDRw177416	rogid:SBy6p7t2Ri6f3a9/Ekk1NFK6WCs9606	intact-crc:81EB00F7B05F7B7C|rigid:0JrA9+gE+yZhWjoEn4Sr/SJhM9I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEC0	uniprotkb:P63261	intact:EBI-2796355|uniprotkb:A0A0G2RN77	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000458162.1|ensembl:ENSP00000458435.1|ensembl:ENSP00000459119.2|ensembl:ENSP00000459124.1|ensembl:ENSP00000460464.2|ensembl:ENSP00000460660.2|ensembl:ENSP00000461672.1|ensembl:ENSP00000466346.2|ensembl:ENSP00000477968.1|ensembl:ENSP00000505060.1|ensembl:ENSP00000505193.1|ensembl:ENSP00000505235.1|ensembl:ENSP00000506126.1|ensembl:ENSP00000506201.1|ensembl:ENSP00000506253.1|ensembl:ENSP00000516869.1|ensembl:ENSP00000516870.1|ensembl:ENSP00000516871.1|ensembl:ENSP00000516872.1|ensembl:ENSP00000516873.1|ensembl:ENSP00000516874.1|ensembl:ENSP00000516875.1|ensembl:ENSP00000516876.1|ensembl:ENSP00000516877.1|ensembl:ENSP00000516879.1|ensembl:ENSP00000516881.1|ensembl:ENSP00000516882.1|ensembl:ENSP00000516884.1|ensembl:ENSP00000516886.1|ensembl:ENSP00000516887.1	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809218|imex:IM-13779-1346	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"efo:""Orphanet:2995""|efo:""Orphanet:90635""|efo:""Orphanet:98942""|efo:""Orphanet:98944""|ensembl:ENSG00000184009.13(gene)|ensembl:ENSG00000291420.1(gene)|ensembl:ENST00000570382.2(transcript)|ensembl:ENST00000571721.6(transcript)|ensembl:ENST00000573283.7(transcript)|ensembl:ENST00000575087.5(transcript)|ensembl:ENST00000575659.6(transcript)|ensembl:ENST00000575842.5(transcript)|ensembl:ENST00000575994.6(transcript)|ensembl:ENST00000576544.6(transcript)|ensembl:ENST00000615544.5(transcript)|ensembl:ENST00000679480.1(transcript)|ensembl:ENST00000679778.1(transcript)|ensembl:ENST00000680227.1(transcript)|ensembl:ENST00000680727.1(transcript)|ensembl:ENST00000681052.1(transcript)|ensembl:ENST00000681842.1(transcript)|ensembl:ENST00000707466.1(transcript)|ensembl:ENST00000707467.1(transcript)|ensembl:ENST00000707468.1(transcript)|ensembl:ENST00000707469.1(transcript)|ensembl:ENST00000707470.1(transcript)|ensembl:ENST00000707471.1(transcript)|ensembl:ENST00000707472.1(transcript)|ensembl:ENST00000707473.1(transcript)|ensembl:ENST00000707474.1(transcript)|ensembl:ENST00000707479.1(transcript)|ensembl:ENST00000707482.1(transcript)|ensembl:ENST00000707485.1(transcript)|ensembl:ENST00000707487.1(transcript)|ensembl:ENST00000707489.1(transcript)|ensembl:ENST00000707490.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005522""(profilin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007409""(axonogenesis)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030016""(myofibril)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031941""(filamentous actin)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048870""(cell motility)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0120192""(tight junction assembly)|go:""GO:0120220""(basal body patch)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902396""(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7NVM|rcsb pdb:8DNF|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|refseq:NP_001186883.1|refseq:NP_001605.1|panther:PTHR11937(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:A693B71432491877|rigid:6nVcPTv17jxRbIOknQ/Uzm+ks10	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NET8	uniprotkb:Q9H6E5	intact:EBI-2797750|uniprotkb:A0A0G2RM76	intact:EBI-2511680|ensembl:ENSP00000419607.1|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|uniprotkb:Q9H6H7|intact:EBI-2809257|uniprotkb:A8K995	psi-mi:q5net8_fratt(display_long)|uniprotkb:hrpA(gene name)|psi-mi:hrpA(display_short)|uniprotkb:FTT_1524c(locus name)	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809260|imex:IM-13779-1351	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170454.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR024590|interpro:IPR010222(RNA helicase, ATP-dependent DEAH box, HrpA type)|interpro:IPR027417|refseq:WP_003022403.1"	"ensembl:ENSG00000149016.16(gene)|ensembl:ENST00000476907.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005847""(mRNA cleavage and polyadenylation specificity factor complex)|go:""GO:0016180""(snRNA processing)|go:""GO:0016607""(nuclear speck)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0034477""(U6 snRNA 3'-end processing)|go:""GO:0046872""(metal ion binding)|go:""GO:0050265""(RNA uridylyltransferase activity)|go:""GO:0140767""(enzyme-substrate adaptor activity)|go:""GO:0180010""(co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway)|go:""GO:1990817""(""poly(A) RNA polymerase activity"")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|interpro:IPR054708|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|rcsb pdb:5WU5|rcsb pdb:5WU6|rcsb pdb:8IDF|refseq:NP_073741.2|dip:DIP-53651N|panther:PTHR12271(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:dwTrOZ+V/pe0RndqVFMFAdvwFAM177416	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	intact-crc:C59DCE30497B527F|rigid:Ujq5LqxBNzSrO9xlHiXka++EVzw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGW8	uniprotkb:O60667	intact:EBI-2803320	intact:EBI-2809270|uniprotkb:A8K7J2|uniprotkb:B7Z6Z0|uniprotkb:D9MWM3|ensembl:ENSP00000356058.3	psi-mi:eno_fratt(display_long)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:FTT_0709(locus name)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)	psi-mi:fcmr_human(display_long)|uniprotkb:Fas apoptotic inhibitory molecule 3(gene name synonym)|uniprotkb:FCMR(gene name)|psi-mi:FCMR(display_short)|uniprotkb:FAIM3(gene name synonym)|uniprotkb:Regulator of Fas-induced apoptosis Toso(gene name synonym)|uniprotkb:TOSO(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809267|imex:IM-13779-1350	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000941(Enolase)|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|refseq:YP_169724.1|go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006096""(glycolytic process)|go:""GO:0009986""(cell surface)|interpro:IPR029017|refseq:WP_003020514.1|interpro:IPR036849"	"refseq:NP_001135945.1|refseq:NP_001180267.1|refseq:NP_005440.1|ensembl:ENSG00000162894.12(gene)|ensembl:ENST00000367091.8(transcript)|go:""GO:0001790""(polymeric immunoglobulin binding)|go:""GO:0001791""(IgM binding)|go:""GO:0002172""(high-affinity IgM receptor activity)|go:""GO:0002414""(immunoglobulin transcytosis in epithelial cells)|go:""GO:0002455""(humoral immune response mediated by circulating immunoglobulin)|go:""GO:0005576""(extracellular region)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006968""(cellular defense response)|go:""GO:0007165""(signal transduction)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0050855""(regulation of B cell receptor signaling pathway)|go:""GO:0160006""(Fc receptor-mediated immune complex endocytosis)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050671|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:7YTE|rcsb pdb:8BPE|rcsb pdb:8BPF|rcsb pdb:8BPG|panther:PTHR11860(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qlcpktC4i/OVSrB7dBccdJhHX2Y177416	rogid:Yt3zQ0fOJl3PACiIx5FPWFC6eQI9606	intact-crc:73DBF44D380B43F5|rigid:WvXT+qsbp3jUGyVC9wtB1jAfke4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A8K451	uniprotkb:Q5NEC0	intact:EBI-2809279	intact:EBI-2796355|uniprotkb:A0A0G2RN77	psi-mi:a8k451_human(display_long)	psi-mi:q5nec0_fratt(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:FTT_1720c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809282|imex:IM-13779-1352	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018155|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005764""(lysosome)|go:""GO:0005975""(carbohydrate metabolic process)"	"go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR029062|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|refseq:YP_170622.1|interpro:IPR040707|refseq:WP_003022688.1|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HPbXzIdcteyj+rAWHNO6iowVfyQ9606	rogid:LsPltwGpIldG0qGRd+XWdEH4L3Y177416	intact-crc:3041BC6BB129E115|rigid:IkWotw1EeUdn4KqjXFMAIo/XJYg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00481	uniprotkb:Q5NHS4	intact:EBI-2809309|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4|ensembl:ENSP00000289361.6	intact:EBI-2798955|uniprotkb:A0A0G2RPB0	psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:q5nhs4_fratt(display_long)|uniprotkb:Folylpolyglutamate synthetase(gene name synonym)|uniprotkb:Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase(gene name synonym)|uniprotkb:folC(gene name)|psi-mi:folC(display_short)|uniprotkb:Tetrahydrofolylpolyglutamate synthase(gene name synonym)|uniprotkb:FTT_0371c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809320|imex:IM-13779-1355	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1|rcsb pdb:8JYE|ensembl:ENSG00000026950.17(gene)|ensembl:ENST00000289361.11(transcript)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0001819""(positive regulation of cytokine production)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0050798""(activated T cell proliferation)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|interpro:IPR050504|interpro:IPR053896|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|rcsb pdb:8DFX|rcsb pdb:8IXV|rcsb pdb:8IZE|rcsb pdb:8IZG|rcsb pdb:8JYC|reactome:R-HSA-8851680|panther:PTHR24100(orthology-group)"	"interpro:IPR001645(Folylpolyglutamate synthetase)|interpro:IPR013221(Mur ligase, central)|refseq:YP_169418.1|go:""GO:0004326""(tetrahydrofolylpolyglutamate synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008841""(dihydrofolate synthase activity)|go:""GO:0046654""(tetrahydrofolate biosynthetic process)|go:""GO:0046656""(folic acid biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_003020032.1|interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR036565|interpro:IPR036615"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606	rogid:yCx5zGRSAd5ahIDsKUCa0YzZPVg177416	intact-crc:9180701A50934887|rigid:BK/UIaTZDS0s4ST4bcYC1pY17As	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NG28	uniprotkb:Q13106	intact:EBI-2802768|uniprotkb:A0A0G2RPI9	intact:EBI-2809343|uniprotkb:Q8NAR0|uniprotkb:Q8IVG7|uniprotkb:A7MCY3|ensembl:ENSP00000421258.2|ensembl:ENSP00000469633.1|ensembl:ENSP00000507206.1	psi-mi:q5ng28_fratt(display_long)|uniprotkb:dacD(gene name)|psi-mi:dacD(display_short)|uniprotkb:FTT_1029(locus name)	psi-mi:zn154_human(display_long)|uniprotkb:ZNF154(gene name)|psi-mi:ZNF154(display_short)|uniprotkb:KIAA2003(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809350|imex:IM-13779-1354	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015956(Penicillin-binding protein-associated)|interpro:IPR018044|interpro:IPR012907(Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal)|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:YP_170014.1|refseq:WP_003021136.1|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|rcsb pdb:6OSU|mint:Q5NG28|interpro:IPR037167"	"refseq:NP_001078853.1|ensembl:ENSG00000179909.16(gene)|ensembl:ENST00000451275.1(transcript)|ensembl:ENST00000512439.6(transcript)|ensembl:ENST00000684351.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|panther:PTHR24377(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EYTPcD8JUkej9Gvps0ogQD5aQ1c177416	rogid:LETBl316LyLOXDbOz9/qV0K6Y5k9606	intact-crc:7EEAF1037DABD0FE|rigid:HJrVdSgK2s0kL12qiW1cTX030Y4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NH21	uniprotkb:Q9BZJ4	intact:EBI-2802084	intact:EBI-2809327|uniprotkb:Q4V9M1|uniprotkb:Q9Y379|uniprotkb:Q9P182|uniprotkb:Q9UF66|uniprotkb:A8JZZ2|uniprotkb:D3DX54|uniprotkb:D3DX51|ensembl:ENSP00000366299.4	psi-mi:lipa_fratt(display_long)|uniprotkb:Lip-syn(gene name synonym)|uniprotkb:Lipoate synthase(gene name synonym)|uniprotkb:Lipoic acid synthase(gene name synonym)|uniprotkb:Sulfur insertion protein LipA(gene name synonym)|uniprotkb:FTT_0653(locus name)|uniprotkb:lipA(gene name)|psi-mi:lipA(display_short)	psi-mi:s2539_human(display_long)|uniprotkb:SLC25A39(gene name)|psi-mi:SLC25A39(display_short)|uniprotkb:Solute carrier family 25 member 39(gene name synonym)|uniprotkb:CGI-69(orf name)|uniprotkb:PRO2163(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809336|imex:IM-13779-1356	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031691|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR003698(Lipoate synthase)|interpro:IPR007197(Radical SAM)|refseq:YP_169671.1|refseq:WP_003018819.1|go:""GO:0005737""(cytoplasm)|go:""GO:0016992""(lipoate synthase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)"	"refseq:NP_001137252.1|refseq:NP_057100.1|ensembl:ENSG00000013306.16(gene)|ensembl:ENST00000377095.10(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0034634""(glutathione transmembrane transporter activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0160007""(glutathione import into mitochondrion)|go:""GO:0170036""(import into the mitochondrion)|interpro:IPR018108|interpro:IPR023395|interpro:IPR045315|mint:Q9BZJ4|panther:PTHR45760(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YeKBcMVW9ShRc09FAZcl3OgmHZM177416	rogid:a8KW+gTl+YYJ2fHkLdljG95atFM9606	intact-crc:85B5C8837091AA6D|rigid:We/tAjpPMTONiZZP8qOuNZadFr4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHN8	uniprotkb:A8K2F4	intact:EBI-2796935	intact:EBI-2809302	"psi-mi:gcspa_fratt(display_long)|uniprotkb:Glycine cleavage system P-protein subunit 1(gene name synonym)|uniprotkb:Glycine decarboxylase subunit 1(gene name synonym)|uniprotkb:gcvPA(gene name)|psi-mi:gcvPA(display_short)|uniprotkb:""Glycine dehydrogenase (aminomethyl-transferring) subunit 1""(gene name synonym)|uniprotkb:FTT_0409(locus name)"	psi-mi:a8k2f4_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809299|imex:IM-13779-1353	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020581|interpro:IPR023010|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:YP_169454.1|go:""GO:0004375""(""glycine dehydrogenase (decarboxylating) activity"")|go:""GO:0009116""(nucleoside metabolic process)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR049315|refseq:WP_003020123.1"	"interpro:IPR004092(Mbt repeat)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR050548|go:""GO:0005634""(nucleus)|go:""GO:0006325""(chromatin organization)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008270""(zinc ion binding)|interpro:IPR002515(Zinc finger, C2HC-type)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4GjGsdcqW3lU2YDf3Bxa+jeqz6E177416	rogid:LK4n1FqSZS022FU2VsdJW++337o9606	intact-crc:ABCAEC452A38F01A|rigid:wAfx11bXCQxR1I/3f7hx82S5aY4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIA8	uniprotkb:A8K3J5	intact:EBI-2800376	intact:EBI-2809289	psi-mi:rf1_fratt(display_long)|uniprotkb:FTT_0168(locus name)|uniprotkb:prfA(gene name)|psi-mi:prfA(display_short)	psi-mi:a8k3j5_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809292|imex:IM-13779-1357	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004373(Peptide chain release factor 1)|refseq:YP_169234.1|go:""GO:0005737""(cytoplasm)|go:""GO:0016149""(translation release factor activity, codon specific)|refseq:WP_003019960.1|interpro:IPR050057|interpro:IPR045853"	"interpro:IPR029209|interpro:IPR019605|interpro:IPR049942|go:""GO:0005739""(mitochondrion)|go:""GO:0007005""(mitochondrion organization)|interpro:IPR036525"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6lZUlvLNR06AfQiCbfXKwNEmHoE177416	rogid:m4amM/H0fBnHbyNHCHbdXtl0WRA9606	intact-crc:4AF0DF767F95F121|rigid:BkUgNf6mrzPcj+D7tk38rXbQBV8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NET6	uniprotkb:A7E1X5	intact:EBI-2797924	intact:EBI-2809357	psi-mi:q5net6_fratt(display_long)|uniprotkb:idh(gene name)|psi-mi:idh(display_short)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:FTT_1526c(locus name)	psi-mi:a7e1x5_human(display_long)|uniprotkb:TAS2R13(gene name)|psi-mi:TAS2R13(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809361|imex:IM-13779-1359	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004450""(""isocitrate dehydrogenase (NADP+) activity"")|go:""GO:0006097""(glyoxylate cycle)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0046872""(metal ion binding)|interpro:IPR004436(Isocitrate dehydrogenase NADP-dependent, monomeric type)|refseq:YP_170456.1"	"interpro:IPR007960(Mammalian taste receptor)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0033038""(bitter taste receptor activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ry19yoO4zUI5UFPKCy6p85QYH8E177416	rogid:mVqQZlho8jZ2mNc8mS42y4jU9oQ9606	intact-crc:8041003C1821ECC2|rigid:Sq8bicsKA3Evm4nP9XlliP+wdwQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2809371	uniprotkb:Q5NHB4	-	intact:EBI-2806470|uniprotkb:A0A0G2RNP6	psi-mi:a6zj97_human(display_short)|psi-mi:EBI-2809371(display_long)	psi-mi:q5nhb4_fratt(display_long)|uniprotkb:FTT_0552(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809368|imex:IM-13779-1358	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A6ZJ97(uniprot-removed-ac)	"interpro:IPR044638|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|refseq:YP_169578.1|go:""GO:0004029""(""aldehyde dehydrogenase (NAD+) activity"")|interpro:IPR029510|refseq:WP_003023258.1|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:Rv5E1n7vpKC1OT8ELP/7+ufCueY177416	intact-crc:87B4CB701E3960C9	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFP9	uniprotkb:Q9UI33	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	intact:EBI-2809380|uniprotkb:Q68K15|uniprotkb:Q8NDX3|uniprotkb:Q9UHM0|uniprotkb:Q9UHE0|uniprotkb:A6NN05|uniprotkb:C9JD48|uniprotkb:C9JR31|ensembl:ENSP00000307599.3|ensembl:ENSP00000499569.1|intact:EBI-28979512	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	psi-mi:scnba_human(display_long)|uniprotkb:SCN11A(gene name)|psi-mi:SCN11A(display_short)|uniprotkb:SCN12A(gene name synonym)|uniprotkb:SNS2(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 5(gene name synonym)|uniprotkb:Sensory neuron sodium channel 2(gene name synonym)|uniprotkb:Sodium channel protein type XI subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.9(gene name synonym)|uniprotkb:hNaN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809377|imex:IM-13779-1360	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	"ensembl:ENSG00000168356.13(gene)|ensembl:ENST00000302328.9(transcript)|ensembl:ENST00000668754.1(transcript)|go:""GO:0001518""(voltage-gated sodium channel complex)|go:""GO:0001966""(thigmotaxis)|go:""GO:0002526""(acute inflammatory response)|go:""GO:0002544""(chronic inflammatory response)|go:""GO:0005248""(voltage-gated sodium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007409""(axonogenesis)|go:""GO:0007623""(circadian rhythm)|go:""GO:0009408""(response to heat)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009644""(response to high light intensity)|go:""GO:0010996""(response to auditory stimulus)|go:""GO:0019228""(neuronal action potential)|go:""GO:0019233""(sensory perception of pain)|go:""GO:0030424""(axon)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0040040""(thermosensory behavior)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043303""(mast cell degranulation)|go:""GO:0044295""(axonal growth cone)|go:""GO:0044299""(C-fiber)|go:""GO:0048870""(cell motility)|go:""GO:0050965""(detection of temperature stimulus involved in sensory perception of pain)|go:""GO:0050966""(detection of mechanical stimulus involved in sensory perception of pain)|go:""GO:0060004""(reflex)|go:""GO:0060073""(micturition)|go:""GO:0060538""(skeletal muscle organ development)|go:""GO:0060840""(artery development)|go:""GO:0061367""(behavioral response to acetic acid induced pain)|go:""GO:0061368""(behavioral response to formalin induced pain)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070417""(cellular response to cold)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0071731""(response to nitric oxide)|go:""GO:0086002""(cardiac muscle cell action potential involved in contraction)|go:""GO:0086010""(membrane depolarization during action potential)|go:""GO:0099610""(action potential initiation)|go:""GO:0141156""(cAMP/PKA signal transduction)|go:""GO:0160025""(sensory perception of itch)|go:""GO:1990408""(calcitonin gene-related peptide receptor signaling pathway)|go:""GO:1990770""(small intestine smooth muscle contraction)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|reactome:R-HSA-445095|reactome:R-HSA-5576892|refseq:NP_001274152.1|refseq:NP_054858.2|refseq:XP_016861138.1|refseq:XP_016861139.1|efo:""Orphanet:306577""|efo:""Orphanet:391392""|efo:""Orphanet:391397""|efo:""Orphanet:46348""|efo:""Orphanet:88642""|efo:""Orphanet:90026""|panther:PTHR45628(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	rogid:djdG2OJ7JSVCPwhKPulX9aMbtWs9606	intact-crc:1320A324A352FED7|rigid:fZaNI1u3tu7PF0MPUid9vy0iKyc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZE8	uniprotkb:Q5NHP5	intact:EBI-2809397|uniprotkb:Q8WWA2|uniprotkb:Q658U7|uniprotkb:B2RB93|uniprotkb:A6NKV6|ensembl:ENSP00000338389.4	intact:EBI-2797363|uniprotkb:A0A0G2RNY4	psi-mi:rm35_human(display_long)|uniprotkb:MRPL35(gene name)|psi-mi:MRPL35(display_short)|uniprotkb:39S ribosomal protein L35, mitochondrial(gene name synonym)|uniprotkb:BM-007(orf name)	psi-mi:q5nhp5_fratt(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:FTT_0402(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809394|imex:IM-13779-1362	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057706.2|refseq:NP_663619.1|ensembl:ENSG00000132313.15(gene)|ensembl:ENST00000337109.9(transcript)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005761""(mitochondrial ribosome)|go:""GO:0005762""(mitochondrial large ribosomal subunit)|go:""GO:0006412""(translation)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR019338|interpro:IPR021137|interpro:IPR037229|mint:Q9NZE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:7OI7|rcsb pdb:7OI8|rcsb pdb:7OI9|rcsb pdb:7OIA|rcsb pdb:7OIB|rcsb pdb:7OIC|rcsb pdb:7OID|rcsb pdb:7OIE|rcsb pdb:7PD3|rcsb pdb:7PO4|rcsb pdb:7QH6|rcsb pdb:7QH7|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8K2A|rcsb pdb:8K2B|rcsb pdb:8OIR|rcsb pdb:8OIT|rcsb pdb:8PK0|rcsb pdb:8QSJ|rcsb pdb:8QU1|rcsb pdb:8QU5|rcsb pdb:8XT0|rcsb pdb:8XT1|rcsb pdb:8XT2|rcsb pdb:8XT3|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR15909(orthology-group)"	"go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0006260""(DNA replication)|go:""GO:0008408""(3'-5' exonuclease activity)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR004805(DNA polymerase III, alpha subunit)|refseq:YP_169447.1|interpro:IPR029460|refseq:WP_003020102.1|interpro:IPR040982|interpro:IPR041931"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qnBAYkLrqSc62X16EcCAI+Yrtaw9606	rogid:DwkzHVE9BAI7dWosyyMu+MR6dHw177416	intact-crc:4AA1087D52BB4408|rigid:TGfnHJy0/RC0QKAOPUEIP6GaWFg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEP4	uniprotkb:P61077	intact:EBI-2802121|uniprotkb:A0A0G2RNJ4	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:q5nep4_fratt(display_long)|uniprotkb:FTT_1576(locus name)	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809409|imex:IM-13779-1361	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_170498.1|refseq:WP_003022484.1|go:""GO:0016020""(membrane)"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qivaxTncNwJ4rDFodbXHR2exiRI177416	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:52F552B4769016E9|rigid:W38K30FUnDOI10W1U0RGpu2kQDU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2809427	uniprotkb:Q5NID2	-	intact:EBI-2796292	psi-mi:a6ncz6_human(display_short)|psi-mi:EBI-2809427(display_long)|uniprotkb:SFXN3(gene name)|psi-mi:SFXN3(display_short)|uniprotkb:hCG_24661(orf name)	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809431|imex:IM-13779-1363	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A6NCZ6(uniprot-removed-ac)	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SMWtHH6r5UXdr+G6JjKLDXlmR349606	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	intact-crc:2A9FE55D035AE023|rigid:7jCiRjejIeiL+TSBlstKFExxJNM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NF37	uniprotkb:P01023	intact:EBI-2798724	intact:EBI-640741|uniprotkb:Q13677|uniprotkb:Q59F47|uniprotkb:Q5QTS0|uniprotkb:Q68DN2|uniprotkb:Q6PIY3|uniprotkb:Q6PN97|ensembl:ENSP00000323929.8	psi-mi:syp_fratt(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:FTT_1412(locus name)	psi-mi:a2mg_human(display_long)|uniprotkb:CPAMD5(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5(gene name synonym)|uniprotkb:A2M(gene name)|psi-mi:A2M(display_short)|uniprotkb:FWP007(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809466|imex:IM-13779-1365	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044140|refseq:YP_170355.1|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|interpro:IPR033730|refseq:WP_003022224.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR045864|interpro:IPR050062"	"refseq:NP_000005.2|refseq:NP_001334352.1|refseq:NP_001334353.1|refseq:NP_001334354.1|ensembl:ENSG00000175899.15(gene)|ensembl:ENST00000318602.12(transcript)|go:""GO:0001553""(luteinization)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|go:""GO:0001869""(negative regulation of complement activation, lectin pathway)|go:""GO:0002020""(protease binding)|go:""GO:0002438""(acute inflammatory response to antigenic stimulus)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0010037""(response to carbon dioxide)|go:""GO:0019838""(growth factor binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0019959""(interleukin-8 binding)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0042802""(identical protein binding)|go:""GO:0043120""(tumor necrosis factor binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048403""(brain-derived neurotrophic factor binding)|go:""GO:0048406""(nerve growth factor binding)|go:""GO:0048863""(stem cell differentiation)|interpro:IPR010916(TonB box, conserved site)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990402""(embryonic liver development)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|interpro:IPR047565|interpro:IPR050473|mint:P01023|rcsb pdb:1BV8|rcsb pdb:2P9R|rcsb pdb:6TAV|rcsb pdb:7O7L|rcsb pdb:7O7M|rcsb pdb:7O7N|rcsb pdb:7O7O|rcsb pdb:7O7P|rcsb pdb:7O7Q|rcsb pdb:7O7R|rcsb pdb:7O7S|rcsb pdb:7VON|rcsb pdb:7VOO|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-1474228|reactome:R-HSA-8963896|dip:DIP-1118N|panther:PTHR11412(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/15	rogid:6/QkU5JRWJEBZMwaR9J83no0ffk177416	rogid:FClLRDrtOWUx0eBBCUfAocx0Q+49606	intact-crc:8FB7C24B573CBA30|rigid:ks3D5gnWQL9P/UKPGoYiwNoU1uo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95859	uniprotkb:Q5NGW2	intact:EBI-2466403|uniprotkb:A4D0V8|uniprotkb:B4DRG6|uniprotkb:Q8N5Y0|intact:EBI-2809454|uniprotkb:Q549U9|ensembl:ENSP00000222747.3|ensembl:ENSP00000397699.1	intact:EBI-2796474|uniprotkb:A0A0G2RND5	psi-mi:tsn12_human(display_long)|uniprotkb:TSPAN12(gene name)|psi-mi:TSPAN12(display_short)|uniprotkb:NET2(gene name synonym)|uniprotkb:TM4SF12(gene name synonym)|uniprotkb:Transmembrane 4 superfamily member 12(gene name synonym)|uniprotkb:Tetraspan NET-2(gene name synonym)|uniprotkb:UNQ774/PRO1568(orf name)	psi-mi:q5ngw2_fratt(display_long)|uniprotkb:FTT_0715(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809451|imex:IM-13779-1364	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106025.9(gene)|ensembl:ENST00000222747.8(transcript)|ensembl:ENST00000415871.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0010842""(retina layer formation)|go:""GO:0016020""(membrane)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0110135""(Norrin signaling pathway)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|refseq:NP_036470.1|refseq:XP_005250296.1|refseq:XP_011514295.1|refseq:XP_011514296.1|refseq:XP_016867401.1|efo:""Orphanet:891""|panther:PTHR19282(orthology-group)"	"go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0004568""(chitinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR029070|refseq:YP_169730.1|interpro:IPR003610(Carbohydrate-binding family V/XII)|interpro:IPR011583(Chitinase II)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_003020524.1|interpro:IPR036116|interpro:IPR036573|interpro:IPR050314"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KXDxb7yBerfJQsOM7ATOdI0EpFU9606	rogid:hPHdF34TD5FCXE5bWyEmg/dd7sg177416	intact-crc:C0375EE2909D6788|rigid:8XxAIAOJp+iL3yDO4XjEwYL3cbY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NID2	uniprotkb:P22897	intact:EBI-2796292	intact:EBI-2809438|uniprotkb:A5PKW3|uniprotkb:Q5VSJ2|uniprotkb:Q5VSK2|ensembl:ENSP00000455897.1	psi-mi:rpob_fratt(display_long)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:FTT_0144(locus name)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)	psi-mi:mrc1_human(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:CLEC13DL(gene name synonym)|uniprotkb:C-type lectin domain family 13 member D-like(gene name synonym)|uniprotkb:CLEC13D(gene name synonym)|uniprotkb:MRC1L1(gene name synonym)|uniprotkb:C-type lectin domain family 13 member D(gene name synonym)|uniprotkb:Macrophage mannose receptor 1-like protein 1(gene name synonym)|uniprotkb:Human mannose receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809444|imex:IM-13779-1366	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:YP_169210.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|refseq:WP_003019908.1|interpro:IPR037033|interpro:IPR037034|interpro:IPR042107"	"refseq:NP_002429.1|ensembl:ENSG00000260314.3(gene)|ensembl:ENST00000569591.3(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071353""(cellular response to interleukin-4)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001304(C-type lectin)|interpro:IPR013806(Kringle-like fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR035992|interpro:IPR036943|interpro:IPR050111|rcsb pdb:1EGG|rcsb pdb:1EGI|rcsb pdb:5XTS|rcsb pdb:5XTW|rcsb pdb:6INN|rcsb pdb:6INO|rcsb pdb:6INU|rcsb pdb:6INV|rcsb pdb:6IOE|rcsb pdb:7JUB|rcsb pdb:7JUC|rcsb pdb:7JUD|rcsb pdb:7JUE|rcsb pdb:7JUF|rcsb pdb:7JUG|rcsb pdb:7JUH|rcsb pdb:7L61|rcsb pdb:7L62|rcsb pdb:7L63|rcsb pdb:7L64|rcsb pdb:7L65|rcsb pdb:7L66|rcsb pdb:7L67|rcsb pdb:7L68|reactome:R-HSA-1236978|reactome:R-HSA-9637628|dip:DIP-101N|panther:PTHR22803(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+oG/97tspnuewXoLTHUJvFJkZMo177416	rogid:DCdy8VX33x8oKcZvP01ylojEspw9606	intact-crc:D02218AD63C3EB2B|rigid:JtOqZ0mJmQ6dHYj1MK33jHdtEYU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFA1	uniprotkb:Q99550	intact:EBI-2797066|uniprotkb:A0A0G2RM98	intact:EBI-2511359|ensembl:ENSP00000475489.1|intact:EBI-2809473|uniprotkb:U3KQ28|uniprotkb:Q9H976|uniprotkb:A6NEE2|uniprotkb:A1L486|uniprotkb:B3KR87|uniprotkb:A0A0A0MTP3	psi-mi:q5nfa1_fratt(display_long)|uniprotkb:FTT_1339c(locus name)	psi-mi:mpp9_human(display_long)|uniprotkb:MPHOSPH9(gene name)|psi-mi:MPHOSPH9(display_short)|uniprotkb:MPP9(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809482|imex:IM-13779-1368	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|refseq:YP_170291.1|interpro:IPR036513|interpro:IPR052706|refseq:WP_003022095.1"	"ensembl:ENSG00000051825.15(gene)|ensembl:ENST00000606320.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0016020""(membrane)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR026636|mint:Q99550|refseq:NP_073619.3|refseq:XP_016874162.1|refseq:XP_016874168.1|refseq:XP_016874169.1|panther:PTHR14926(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6Zt8IB73d/bI77NTYHhVCWhbQ0U177416	rogid:J1FkA3DERPWTHe57z9hMj6V52xI9606	intact-crc:A254BBAF3CA4FD39|rigid:BvuFVbs+8I6no9WFOSmpiJlnx3k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NQ94	uniprotkb:Q5NFN4	intact:EBI-2809489|uniprotkb:A1L4F2|uniprotkb:Q9NQX9|uniprotkb:Q9NQX8|uniprotkb:Q9NZD3|uniprotkb:Q9NXC9|uniprotkb:Q5SZQ0|uniprotkb:B7ZM14|uniprotkb:Q9NQ93|uniprotkb:A8K7G7|intact:EBI-25633521|ensembl:ENSP00000363105.1	intact:EBI-2796796	psi-mi:a1cf_human(display_long)|uniprotkb:A1CF(gene name)|psi-mi:A1CF(display_short)|uniprotkb:ACF(gene name synonym)|uniprotkb:ASP(gene name synonym)|uniprotkb:APOBEC1-stimulating protein(gene name synonym)	psi-mi:uvrb_fratt(display_long)|uniprotkb:Excinuclease ABC subunit B(gene name synonym)|uniprotkb:FTT_1199c(locus name)|uniprotkb:uvrB(gene name)|psi-mi:uvrB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809502|imex:IM-13779-1367	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001185747.1|refseq:NP_001185748.1|refseq:NP_001185749.1|refseq:NP_055391.2|refseq:NP_620310.1|refseq:NP_620311.1|refseq:XP_005269775.1|refseq:XP_005269777.1|ensembl:ENSG00000148584.16(gene)|ensembl:ENST00000373993.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006397""(mRNA processing)|go:""GO:0007566""(embryo implantation)|go:""GO:0010609""(mRNA localization resulting in post-transcriptional regulation of gene expression)|go:""GO:0016554""(cytidine to uridine editing)|go:""GO:0016556""(mRNA modification)|go:""GO:0030895""(apolipoprotein B mRNA editing enzyme complex)|go:""GO:0045293""(mRNA editing complex)|go:""GO:0050821""(protein stabilization)|go:""GO:0140767""(enzyme-substrate adaptor activity)|go:""GO:0141166""(chromosomal 5-methylcytosine DNA demethylation pathway)|go:""GO:2000623""(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034538|interpro:IPR035979|interpro:IPR044461|rcsb pdb:2CPD|reactome:R-HSA-72200|reactome:R-HSA-75094|refseq:XP_016871649.1|panther:PTHR21245(orthology-group)"	"go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_170158.1|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004807(Excinuclease ABC, B subunit)|interpro:IPR024759|interpro:IPR027417|interpro:IPR036876|interpro:IPR041471|refseq:WP_003021449.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DNqEVi2Wrp6+hUJL/A26bKl0OSE9606	rogid:Jhq9KYkHYrpyhq5qkOrHkcqCWVk177416	intact-crc:401B07012693F89F|rigid:KkpWjMBQMolxhvoNODdpFZDtLmI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IZ83	uniprotkb:Q5NIJ6	intact:EBI-1044483|uniprotkb:C9JBH6|uniprotkb:Q86YF0|uniprotkb:Q8IYL4|uniprotkb:Q8TEI8|uniprotkb:B4DLQ1|ensembl:ENSP00000293350.3	intact:EBI-2798981	psi-mi:a16a1_human(display_long)|uniprotkb:ALDH16A1(gene name)|psi-mi:ALDH16A1(display_short)	psi-mi:q5nij6_fratt(display_long)|uniprotkb:gltA(gene name)|psi-mi:gltA(display_short)|uniprotkb:FTT_0071c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809509|imex:IM-13779-1369	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_699160.2|refseq:NP_001138868.1|ensembl:ENSG00000161618.10(gene)|ensembl:ENST00000293350.9(transcript)|go:""GO:0016020""(membrane)|go:""GO:0016620""(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q8IZ83|panther:PTHR11699(orthology-group)"	"refseq:YP_169146.1|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR019810|interpro:IPR024176|interpro:IPR010953(Citrate synthase, type II)|rcsb pdb:3MSU|go:""GO:0004108""(""citrate (Si)-synthase activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0046872""(metal ion binding)|interpro:IPR036969|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BoCNAGkgDh2oJaclyaoXr117+iw9606	rogid:qzZqwzEZgr2bUdZ1yHJS+SziucQ177416	intact-crc:CDC94C492C075701|rigid:G8Ya2p893G8rykcj8GaxpKD/bkg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0M8X1	uniprotkb:Q5NHI7	intact:EBI-2809519	intact:EBI-2798777	psi-mi:a0m8x1_human(display_long)|uniprotkb:TPO(gene name)|psi-mi:TPO(display_short)	psi-mi:lptd_fratt(display_long)|uniprotkb:imp(gene name synonym)|uniprotkb:ostA(gene name synonym)|uniprotkb:FTT_0467(locus name)|uniprotkb:lptD(gene name)|psi-mi:lptD(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809516|imex:IM-13779-1370	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR018097|interpro:IPR010255(Haem peroxidase)|interpro:IPR019791|interpro:IPR000436(Sushi/SCR/CCP)|go:""GO:0004447""(iodide peroxidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0006590""(thyroid hormone generation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0042446""(hormone biosynthetic process)|go:""GO:0042744""(hydrogen peroxide catabolic process)|interpro:IPR029589|interpro:IPR035976|interpro:IPR037120|interpro:IPR049883"	"interpro:IPR020889|interpro:IPR005653(OstA-like protein)|interpro:IPR007543(Organic solvent tolerance protein)|refseq:YP_169505.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015920""(lipopolysaccharide transport)|go:""GO:0043165""(Gram-negative-bacterium-type cell outer membrane assembly)|go:""GO:1990351""(transporter complex)|refseq:WP_003023202.1|interpro:IPR050218"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RPriEBzhuAV0O3XnBzEKuYe1VB49606	rogid:/bT7iXIL9hXmyxrwsNnQOnA1/g4177416	intact-crc:71CAD7502CC81AFF|rigid:M+Zhb0jPu4liNis/smPHYYE+N4U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFY7	uniprotkb:A0JNV7	intact:EBI-2801535	intact:EBI-2809527	psi-mi:q5nfy7_fratt(display_long)|uniprotkb:hipA(gene name)|psi-mi:hipA(display_short)|uniprotkb:FTT_1076(locus name)	psi-mi:a0jnv7_human(display_long)|uniprotkb:EMR2(gene name)|psi-mi:EMR2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809531|imex:IM-13779-1372	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_170055.1|interpro:IPR012893(HipA-like, C-terminal)|interpro:IPR017508(HipA, N-terminal)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005829""(cytosol)|interpro:IPR052028"	"refseq:NP_001257981.1|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR018097|interpro:IPR017981|interpro:IPR003056(GPCR, family 2, CD97 antigen)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR017983|interpro:IPR000203(GPS)|refseq:NP_038475.2|interpro:IPR009030(Growth factor, receptor)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|interpro:IPR049883|interpro:IPR046338"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Zoq1f35Rowm1oHbCdDCkCzRBmKI177416	rogid:Hg9r2I+WEfBk5O/yJPn1evuVuMc9606	intact-crc:01AD9D482EFC7C3A|rigid:GO0uuen/yKxcbwPfF+NLfCHiz78	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFD3	uniprotkb:Q9NRA8	intact:EBI-2801650	intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|intact:EBI-877635|ensembl:ENSP00000328103.5|ensembl:ENSP00000380659.1|uniprotkb:B1AKL3	psi-mi:q5nfd3_fratt(display_long)|uniprotkb:Enoylpyruvate transferase(gene name synonym)|uniprotkb:UDP-N-acetylglucosamine enolpyruvyl transferase(gene name synonym)|uniprotkb:FTT_1305c(locus name)|uniprotkb:murA(gene name)|psi-mi:murA(display_short)	psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809545|imex:IM-13779-1373	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001986(3-phosphoshikimate 1-carboxyvinyltransferase, core)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|refseq:YP_170259.1|go:""GO:0005737""(cytoplasm)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008760""(UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0051301""(cell division)|go:""GO:0071555""(cell wall organization)|interpro:IPR036968|interpro:IPR050068"	"ensembl:ENSG00000184708.18(gene)|ensembl:ENST00000330125.10(transcript)|ensembl:ENST00000397525.5(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0016020""(membrane)|go:""GO:0016605""(PML body)|go:""GO:0016607""(nuclear speck)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0019900""(kinase binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0033962""(P-body assembly)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0106289""(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_016884353.1|panther:PTHR12269(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Y5bBF/SOGGTHVDU1XtjyyhDJOYc177416	rogid:4A9mF81S/ePAraruTNYgovUdkT49606	intact-crc:8CA4508291F7694E|rigid:392otqM3EkRKoBZ0XwyvZ3UtPJk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NIB3	uniprotkb:P49902	intact:EBI-2805819|uniprotkb:A0A0G2RPX7	intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|uniprotkb:B7Z382|ensembl:ENSP00000339479.5|ensembl:ENSP00000383960.3|ensembl:ENSP00000501689.1|ensembl:ENSP00000502205.1|ensembl:ENSP00000502679.1|ensembl:ENSP00000502801.1	psi-mi:q5nib3_fratt(display_long)|uniprotkb:parE(gene name)|psi-mi:parE(display_short)|uniprotkb:Topoisomerase IV subunit B(gene name synonym)|uniprotkb:FTT_0163c(locus name)	psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym)|uniprotkb:Cytosolic IMP/GMP-specific 5'-nucleotidase(gene name synonym)|uniprotkb:Cytosolic nucleoside phosphotransferase 5'N(gene name synonym)|uniprotkb:High Km 5'-nucleotidase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809538|imex:IM-13779-1371	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169229.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR005737(DNA topoisomerase IV, subunit B, Gram-negative)|interpro:IPR006171(TOPRIM)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0006265""(DNA topological change)|go:""GO:0007059""(chromosome segregation)|go:""GO:0034335""(DNA negative supercoiling activity)|refseq:WP_003019941.1|interpro:IPR036890"	"ensembl:ENSG00000076685.19(gene)|ensembl:ENST00000343289.9(transcript)|ensembl:ENST00000404739.8(transcript)|ensembl:ENST00000674696.1(transcript)|ensembl:ENST00000675326.1(transcript)|ensembl:ENST00000676428.1(transcript)|ensembl:ENST00000676449.1(transcript)|go:""GO:0000255""(allantoin metabolic process)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006204""(IMP catabolic process)|go:""GO:0008253""(5'-nucleotidase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0046037""(GMP metabolic process)|go:""GO:0046040""(IMP metabolic process)|go:""GO:0046054""(dGMP metabolic process)|go:""GO:0046085""(adenosine metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050146""(nucleoside phosphotransferase activity)|go:""GO:0050483""(obsolete IMP 5'-nucleotidase activity)|go:""GO:0050484""(obsolete GMP 5'-nucleotidase activity)|go:""GO:0050689""(negative regulation of defense response to virus by host)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0106411""(obsolete XMP 5'-nucleosidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|rcsb pdb:6FIW|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|reactome:R-HSA-9755088|refseq:NP_001127845.1|refseq:NP_036361.1|refseq:XP_005269693.1|refseq:XP_005269696.1|efo:""Orphanet:320396""|panther:PTHR12103(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eSUwaDHwHNDsicxk7YgYrDfmnIE177416	rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606	intact-crc:B0081059304B48FA|rigid:j/0YM80TuGF9HE1GQ+S8ln61Zb8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NFC1	uniprotkb:P01903	intact:EBI-2804619|uniprotkb:A0A0G2RQ47	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608.2|ensembl:ENSP00000372746.2|ensembl:ENSP00000378786.2|ensembl:ENSP00000402951.2|ensembl:ENSP00000404533.2|ensembl:ENSP00000405295.2|ensembl:ENSP00000410443.2|ensembl:ENSP00000479287.1	psi-mi:q5nfc1_fratt(display_long)|uniprotkb:Leucine aminopeptidase(gene name synonym)|uniprotkb:Leucyl aminopeptidase(gene name synonym)|uniprotkb:pepA(gene name)|psi-mi:pepA(display_short)|uniprotkb:FTT_1318c(locus name)	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809566|imex:IM-13779-1378	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023042|interpro:IPR011356(Peptidase M17, leucyl aminopeptidase)|interpro:IPR000819(Peptidase M17, leucyl aminopeptidase, C-terminal)|interpro:IPR008283(Peptidase M17, leucyl aminopeptidase, N-terminal)|refseq:YP_170271.1|rcsb pdb:3PEI|interpro:IPR043472|go:""GO:0005737""(cytoplasm)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|refseq:WP_003016784.1"	"dip:DIP-6063N|efo:""Orphanet:505""|ensembl:ENSG00000204287.14(gene)|ensembl:ENSG00000206308.11(gene)|ensembl:ENSG00000226260.9(gene)|ensembl:ENSG00000227993.9(gene)|ensembl:ENSG00000228987.9(gene)|ensembl:ENSG00000230726.9(gene)|ensembl:ENSG00000234794.9(gene)|ensembl:ENSG00000277263.1(gene)|ensembl:ENST00000383127.6(transcript)|ensembl:ENST00000383259.6(transcript)|ensembl:ENST00000395388.7(transcript)|ensembl:ENST00000411524.6(transcript)|ensembl:ENST00000414698.6(transcript)|ensembl:ENST00000416883.6(transcript)|ensembl:ENST00000442960.6(transcript)|ensembl:ENST00000613328.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050890""(cognition)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01903|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:1ZGL|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:7N19|rcsb pdb:7NZE|rcsb pdb:7O00|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8CMB|rcsb pdb:8CMC|rcsb pdb:8CMD|rcsb pdb:8CME|rcsb pdb:8CMF|rcsb pdb:8CMG|rcsb pdb:8CMH|rcsb pdb:8CMI|rcsb pdb:8EUQ|rcsb pdb:8PJE|rcsb pdb:8PJF|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:9B7B|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_061984.2|panther:PTHR19944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zmgvN096sZv3fesDbF3AjymhTQo177416	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	intact-crc:670F691E18EE5D2E|rigid:IE5kgdRfw/ufxTvvHJkISO2xKKc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10321	uniprotkb:Q5NHH2	intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402.5	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809580|imex:IM-13779-1375	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204525.18(gene)|ensembl:ENST00000376228.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_002108.4|efo:""Orphanet:585909""|panther:PTHR16675(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:0700071CFB3ED11F|rigid:iUOkaishEVBNp5L2kQ6c7cjlQpg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01903	uniprotkb:Q5NGF1	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608.2|ensembl:ENSP00000372746.2|ensembl:ENSP00000378786.2|ensembl:ENSP00000402951.2|ensembl:ENSP00000404533.2|ensembl:ENSP00000405295.2|ensembl:ENSP00000410443.2|ensembl:ENSP00000479287.1	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809559|imex:IM-13779-1377	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-6063N|efo:""Orphanet:505""|ensembl:ENSG00000204287.14(gene)|ensembl:ENSG00000206308.11(gene)|ensembl:ENSG00000226260.9(gene)|ensembl:ENSG00000227993.9(gene)|ensembl:ENSG00000228987.9(gene)|ensembl:ENSG00000230726.9(gene)|ensembl:ENSG00000234794.9(gene)|ensembl:ENSG00000277263.1(gene)|ensembl:ENST00000383127.6(transcript)|ensembl:ENST00000383259.6(transcript)|ensembl:ENST00000395388.7(transcript)|ensembl:ENST00000411524.6(transcript)|ensembl:ENST00000414698.6(transcript)|ensembl:ENST00000416883.6(transcript)|ensembl:ENST00000442960.6(transcript)|ensembl:ENST00000613328.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050890""(cognition)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01903|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:1ZGL|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:7N19|rcsb pdb:7NZE|rcsb pdb:7O00|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8CMB|rcsb pdb:8CMC|rcsb pdb:8CMD|rcsb pdb:8CME|rcsb pdb:8CMF|rcsb pdb:8CMG|rcsb pdb:8CMH|rcsb pdb:8CMI|rcsb pdb:8EUQ|rcsb pdb:8PJE|rcsb pdb:8PJF|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:9B7B|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_061984.2|panther:PTHR19944(orthology-group)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	intact-crc:3F67181E18EF7270|rigid:fEelxh4LpII/X73zZK1nibY9oTQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGF1	uniprotkb:P11171	intact:EBI-2797546|uniprotkb:A0A0G2RPU1	intact:EBI-1050906|uniprotkb:P11176|uniprotkb:Q14245|uniprotkb:Q5TB35|uniprotkb:Q5VXN8|uniprotkb:Q8IXV9|uniprotkb:Q9Y578|uniprotkb:Q9Y579|uniprotkb:B1ALH8|uniprotkb:B1ALH9|uniprotkb:D3DPM9|uniprotkb:D3DPN0|ensembl:ENSP00000345259.4|ensembl:ENSP00000362904.1	psi-mi:q5ngf1_fratt(display_long)|uniprotkb:purCD(gene name)|psi-mi:purCD(display_short)|uniprotkb:purD(gene name synonym)|uniprotkb:purC(gene name synonym)|uniprotkb:FTT_0894(locus name)	psi-mi:epb41_human(display_long)|uniprotkb:Band 4.1(gene name synonym)|uniprotkb:EPB4.1(gene name synonym)|uniprotkb:4.1R(gene name synonym)|uniprotkb:EPB41(gene name)|psi-mi:EPB41(display_short)|uniprotkb:E41P(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809552|imex:IM-13779-1374	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_169891.1|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR018236|interpro:IPR028923|refseq:WP_003020892.1|interpro:IPR037123"	"dip:DIP-17032N|ensembl:ENSG00000159023.23(gene)|ensembl:ENST00000343067.9(transcript)|ensembl:ENST00000373798.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005545""(1-phosphatidylinositol binding)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0014731""(spectrin-associated cytoskeleton)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030507""(spectrin binding)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045171""(intercellular bridge)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051301""(cell division)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0072686""(mitotic spindle)|go:""GO:1904478""(regulation of intestinal absorption)|go:""GO:1904778""(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR021187|interpro:IPR029071|interpro:IPR035963|mint:P11171|rcsb pdb:1GG3|rcsb pdb:2RQ1|rcsb pdb:3QIJ|reactome:R-HSA-6794361|refseq:NP_001159477.1|refseq:NP_001159478.1|refseq:NP_004428.1|refseq:NP_976217.1|refseq:XP_005245818.1|refseq:XP_005245821.1|refseq:XP_016856078.1|efo:""Orphanet:288""|panther:PTHR23280(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4PGd8IkEeH0UDNxRluLiCZbpaWQ177416	rogid:ZCaM+kjScfGP23wRkFRwVyxOyvk9606	intact-crc:E274520C760DC2CE|rigid:QFxKvni8crH9LaGbgo8h2ZXI5xU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10321	uniprotkb:Q5NHX5	intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402.5	intact:EBI-2801674|uniprotkb:A0A0G2RNV9	psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)	psi-mi:q5nhx5_fratt(display_long)|uniprotkb:cdsA(gene name)|psi-mi:cdsA(display_short)|uniprotkb:FTT_0318(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809573|imex:IM-13779-1376	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204525.18(gene)|ensembl:ENST00000376228.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_002108.4|efo:""Orphanet:585909""|panther:PTHR16675(orthology-group)"	"interpro:IPR000374(Phosphatidate cytidylyltransferase)|refseq:YP_169367.1|go:""GO:0004605""(phosphatidate cytidylyltransferase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0016024""(CDP-diacylglycerol biosynthetic process)|refseq:WP_003021609.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606	rogid:j4nia2AICT6hhJFTrk/Er4tDCe8177416	intact-crc:B710071CFAADE286|rigid:gcIk2ZzDpsaLkjHSEufM9jc2ZV4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NG97	uniprotkb:P01889	intact:EBI-2808955|uniprotkb:A0A0G2RQ99	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	psi-mi:q5ng97_fratt(display_long)|uniprotkb:gor(gene name)|psi-mi:gor(display_short)|uniprotkb:FTT_0955c(locus name)	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809608|imex:IM-13779-1383	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR006322(Glutathione reductase, animal and bacterial)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|refseq:YP_169945.1|go:""GO:0004362""(""glutathione-disulfide reductase (NADPH) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0050661""(NADP binding)|refseq:WP_003021023.1|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR036188|interpro:IPR046952"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:biZgZ28/rnr4Brcut9/Trv0Y4d0177416	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	intact-crc:BC446B6B071CD896|rigid:CDeya2ze83l/h5ByTjwMN3HkkqA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHX0	uniprotkb:P10321	intact:EBI-2799263	intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402.5	psi-mi:efg_fratt(display_long)|uniprotkb:FTT_0323(locus name)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)	psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809601|imex:IM-13779-1379	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_169372.1|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR031157|refseq:WP_003028885.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|interpro:IPR047872"	"ensembl:ENSG00000204525.18(gene)|ensembl:ENST00000376228.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_002108.4|efo:""Orphanet:585909""|panther:PTHR16675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:hULyXsLqQVOFqECbDOTlNV2kzrY177416	rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606	intact-crc:4210071CFB82E01A|rigid:FnItCorCuYVeksgQFzjNQk8oXsg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NEN3	uniprotkb:P10321	intact:EBI-2806593	intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402.5	psi-mi:q5nen3_fratt(display_long)|uniprotkb:FTT_1591(locus name)	psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809594|imex:IM-13779-1382	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007428(VacJ-like lipoprotein)|refseq:YP_170509.1|go:""GO:0016020""(membrane)|go:""GO:0120010""(intermembrane phospholipid transfer)"	"ensembl:ENSG00000204525.18(gene)|ensembl:ENST00000376228.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_002108.4|efo:""Orphanet:585909""|panther:PTHR16675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:nuOlvTUFuKENrRhUMqrKgIrW+Yo177416	rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606	intact-crc:CC653A1CFB63E7AD|rigid:FaCAQpicy3BVZhJ1k+9tm/eA2jo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01889	uniprotkb:Q4VP87	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	intact:EBI-2796861	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:q4vp87_fratl(display_long)|uniprotkb:FTT0445(orf name)|uniprotkb:uup(gene name)|psi-mi:uup(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:119856(fratl)|taxid:119856(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809615|imex:IM-13779-1381	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"go:""GO:0005524""(ATP binding)|interpro:IPR027417|interpro:IPR032781|interpro:IPR051309"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	rogid:+Qbmzj8eW72wb4LBUxcHkhpPQRE119856	intact-crc:C507C02E761C8037|rigid:Gy3cPBjfhWdIZBxTiCBHT+Y0fAw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NGY2	uniprotkb:P10321	intact:EBI-2797917|uniprotkb:A0A0G2RM93	intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402.5	psi-mi:q5ngy2_fratt(display_long)|uniprotkb:FTT_0694(locus name)	psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809587|imex:IM-13779-1380	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016405""(CoA-ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|refseq:YP_169710.1|refseq:WP_003020490.1"	"ensembl:ENSG00000204525.18(gene)|ensembl:ENST00000376228.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_002108.4|efo:""Orphanet:585909""|panther:PTHR16675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:YJytAX3dIfk7mcu7c3zHvFqWwCY177416	rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606	intact-crc:8998D81CFB3B4166|rigid:JpT/xO3LRS7+0SUDEWjTwbW3UzM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92736	uniprotkb:Q81Z75	intact:EBI-1170425|uniprotkb:Q15411|uniprotkb:Q546N8|uniprotkb:Q5T3P2|ensembl:ENSP00000355533.2	intact:EBI-2809631|uniprotkb:Q6KXS8|uniprotkb:E9QUA4	psi-mi:ryr2_human(display_long)|uniprotkb:RYR2(gene name)|psi-mi:RYR2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:q81z75_bacan(display_long)|uniprotkb:GBAA_0397(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809635|imex:IM-13779-1384	author score:20|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR46399(orthology-group)|dip:DIP-38325N|ensembl:ENSG00000198626.19(gene)|ensembl:ENST00000366574.7(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0003143""(embryonic heart tube morphogenesis)|go:""GO:0003220""(left ventricular cardiac muscle tissue morphogenesis)|go:""GO:0003300""(cardiac muscle hypertrophy)|go:""GO:0005219""(ryanodine-sensitive calcium-release channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005513""(detection of calcium ion)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006941""(striated muscle contraction)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0010882""(regulation of cardiac muscle contraction by calcium ion signaling)|go:""GO:0014701""(junctional sarcoplasmic reticulum membrane)|go:""GO:0014808""(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015278""(intracellularly gated calcium channel activity)|go:""GO:0016020""(membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019899""(enzyme binding)|go:""GO:0030018""(Z disc)|go:""GO:0031000""(response to caffeine)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|go:""GO:0034704""(calcium channel complex)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0042383""(sarcolemma)|go:""GO:0042802""(identical protein binding)|go:""GO:0043924""(suramin binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0048763""(calcium-induced calcium release activity)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051284""(positive regulation of sequestering of calcium ion)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051775""(response to redox state)|go:""GO:0055117""(regulation of cardiac muscle contraction)|go:""GO:0060048""(cardiac muscle contraction)|go:""GO:0060402""(calcium ion transport into cytosol)|go:""GO:0070296""(sarcoplasmic reticulum calcium ion transport)|go:""GO:0071313""(cellular response to caffeine)|go:""GO:0071872""(cellular response to epinephrine stimulus)|go:""GO:0072599""(establishment of protein localization to endoplasmic reticulum)|go:""GO:0086005""(ventricular cardiac muscle cell action potential)|go:""GO:0086029""(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:0097050""(type B pancreatic cell apoptotic process)|go:""GO:0098735""(positive regulation of the force of heart contraction)|go:""GO:0098904""(regulation of AV node cell action potential)|go:""GO:0098907""(regulation of SA node cell action potential)|go:""GO:0098910""(regulation of atrial cardiac muscle cell action potential)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR015925(Ryanodine receptor-related)|interpro:IPR016093(MIR motif)|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|interpro:IPR048581|mint:Q92736|rcsb pdb:4JKQ|rcsb pdb:6Y4O|rcsb pdb:6Y4P|rcsb pdb:7KL5|rcsb pdb:7U9Q|rcsb pdb:7U9R|rcsb pdb:7U9T|rcsb pdb:7U9X|rcsb pdb:7U9Z|rcsb pdb:7UA1|rcsb pdb:7UA3|rcsb pdb:7UA4|rcsb pdb:7UA5|rcsb pdb:7UA9|rcsb pdb:8UQ2|rcsb pdb:8UQ3|rcsb pdb:8UQ4|rcsb pdb:8UQ5|rcsb pdb:8UXC|rcsb pdb:8UXE|rcsb pdb:8UXF|rcsb pdb:8UXG|rcsb pdb:8UXH|rcsb pdb:8UXI|rcsb pdb:8UXL|rcsb pdb:8UXM|reactome:R-HSA-2672351|reactome:R-HSA-5578775|refseq:NP_001026.2|refseq:XP_006711868.1|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:3286"""	"refseq:WP_000161178.1|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Z3eTbcvvaCLOKWelrdkxMso6IT89606	rogid:5bjDxf1Ab9R5iOfEMs3IVYjFxcE1392	intact-crc:D75DA785776E430C|rigid:JxZH574IaDSo7WWsIUUnTO7200s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P52907	uniprotkb:A0A6L7HKR6	intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168.3	intact:EBI-2809642|uniprotkb:Q6KUH0|uniprotkb:Q6I0K8|uniprotkb:E9QQW7|uniprotkb:E9QQW8|uniprotkb:Q81SC4|uniprotkb:A0A1J9VQ05	psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym)	psi-mi:a0a6l7hkr6_bacan(display_long)|uniprotkb:GBAA_1736(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809647|imex:IM-13779-1386	author score:16|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006126.1|ensembl:ENSG00000116489.13(gene)|ensembl:ENST00000263168.4(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0034329""(cell junction assembly)|go:""GO:0045296""(cadherin binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071203""(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|rcsb pdb:7T5Q|rcsb pdb:8F8Q|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231|panther:PTHR10653(orthology-group)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_000248182.1|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|interpro:IPR035906"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606	rogid:PkhImEA4CFkMslskljinZel4Qqc1392	intact-crc:6B10F373E76CC0E7|rigid:UNiCkFUvsJAw/3dAYheaOaVj09k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HC45	uniprotkb:Q9Y2F9	intact:EBI-2809657|uniprotkb:Q6KY59|uniprotkb:Q6I4F7|uniprotkb:E9R9C7|uniprotkb:E9R9C8|uniprotkb:Q81VF6|uniprotkb:A0A0F7R3Y0	intact:EBI-311155|uniprotkb:Q5JY73|uniprotkb:D3DW19|ensembl:ENSP00000367471.2|ensembl:ENSP00000384545.1	psi-mi:a0a6l7hc45_bacan(display_long)|uniprotkb:dal1(gene name)|psi-mi:dal1(display_short)|uniprotkb:GBAA_0252(locus name)	psi-mi:btbd3_human(display_long)|uniprotkb:BTBD3(gene name)|psi-mi:BTBD3(display_short)|uniprotkb:KIAA0952(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809654|imex:IM-13779-1385	author score:16|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000821(Alanine racemase region)|interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR011079(Alanine racemase, C-terminal)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR020622|rcsb pdb:2VD8|rcsb pdb:2VD9|rcsb pdb:3HA1|interpro:IPR029066|go:""GO:0005829""(cytosol)|go:""GO:0008784""(alanine racemase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0030632""(D-alanine biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000390596.1"	"refseq:NP_055777.1|refseq:NP_001269479.1|refseq:NP_001269480.1|refseq:NP_852108.2|ensembl:ENSG00000132640.15(gene)|ensembl:ENST00000378226.7(transcript)|ensembl:ENST00000405977.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0022008""(neurogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0048813""(dendrite morphogenesis)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR012983(PHR)|interpro:IPR038648|refseq:XP_016883217.1|refseq:XP_016883218.1|panther:PTHR45774(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tICAk3r2Xr8ULVs416LlRofG2IA1392	rogid:48rwcG9S42qImmpRdRgRQgvyqYE9606	intact-crc:4C0982855FEEF9BD|rigid:5zz0VSSbMg4HeRa5oP7cDpOS8lw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49795	uniprotkb:A0A6L7HI94	intact:EBI-874907|uniprotkb:Q53XN0|uniprotkb:Q8TD60|uniprotkb:A8K216|uniprotkb:E1P5G9|ensembl:ENSP00000333194.5|ensembl:ENSP00000378483.1	intact:EBI-2809670|uniprotkb:Q6KUB6|uniprotkb:Q6I0E9|uniprotkb:E9QZ71|uniprotkb:E9QZ72|uniprotkb:Q81S67|uniprotkb:A0A0F7RKN4	psi-mi:rgs19_human(display_long)|uniprotkb:G-alpha-interacting protein(gene name synonym)|uniprotkb:RGS19(gene name)|psi-mi:RGS19(display_short)|uniprotkb:GAIP(gene name synonym)|uniprotkb:GNAI3IP(gene name synonym)	psi-mi:a0a6l7hi94_bacan(display_long)|uniprotkb:GBAA_1804(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809667|imex:IM-13779-1388	author score:15|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011526787.1|refseq:XP_011526788.1|refseq:NP_001034556.1|refseq:NP_005864.1|panther:PTHR10845(orthology-group)|ensembl:ENSG00000171700.14(gene)|ensembl:ENST00000332298.9(transcript)|ensembl:ENST00000395042.2(transcript)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0006914""(autophagy)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0009968""(negative regulation of signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0045471""(response to ethanol)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR036305|interpro:IPR044926|mint:P49795|rcsb pdb:1CMZ|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-418597"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR013663(Helicase, SWF/SNF/SWI type, bacterial)|interpro:IPR000330(SNF2-related)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR038718|interpro:IPR027417|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016787""(hydrolase activity)|refseq:WP_000507070.1|interpro:IPR049730"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lGw7GXTwMFo5aFKUn8B4tlkZ8rM9606	rogid:UALwsYQ6P5Vi+Y6Ffzu+ItCyX2Y1392	intact-crc:D3C59290D547497B|rigid:fpxvpGfNzAelglvwOZnsngZDQCM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PJ09	uniprotkb:Q8IV08	intact:EBI-2809683|uniprotkb:Q6KTR5|uniprotkb:Q6HZT0|uniprotkb:E9QXV8|uniprotkb:E9QXV9|uniprotkb:Q81RK3	intact:EBI-2689908|uniprotkb:Q9BW87|uniprotkb:Q92853|intact:EBI-40264531|ensembl:ENSP00000348901.5|ensembl:ENSP00000386293.1|ensembl:ENSP00000386938.3|ensembl:ENSP00000387022.1|ensembl:ENSP00000387050.1|ensembl:ENSP00000515107.1|ensembl:ENSP00000515110.1|ensembl:ENSP00000515111.1|ensembl:ENSP00000515112.1|ensembl:ENSP00000515113.1|ensembl:ENSP00000515115.1|ensembl:ENSP00000515116.1|ensembl:ENSP00000515117.1|ensembl:ENSP00000515118.1|ensembl:ENSP00000515119.1|ensembl:ENSP00000515120.1|ensembl:ENSP00000515121.1|ensembl:ENSP00000515122.1|ensembl:ENSP00000515123.1	psi-mi:a0a6l8pj09_bacan(display_long)|uniprotkb:GBAA_2041(locus name)	"psi-mi:pld3_human(display_long)|uniprotkb:HindIII K4L homolog(gene name synonym)|uniprotkb:Hu-K4(gene name synonym)|uniprotkb:Phospholipase D3(gene name synonym)|uniprotkb:PLD3(gene name)|psi-mi:PLD3(display_short)|uniprotkb:""(S,S)-bis(monoacylglycero)phosphate synthase PLD3""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809680|imex:IM-13779-1387	author score:15|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039424|interpro:IPR000914(Bacterial extracellular solute-binding protein, family 5)|refseq:WP_000824542.1|go:""GO:0015833""(peptide transport)|go:""GO:0030313""(cell envelope)|go:""GO:0042597""(periplasmic space)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|go:""GO:1904680""(peptide transmembrane transporter activity)|interpro:IPR030678"	"efo:""Orphanet:589522""|ensembl:ENSG00000105223.21(gene)|ensembl:ENST00000356508.9(transcript)|ensembl:ENST00000409281.5(transcript)|ensembl:ENST00000409419.5(transcript)|ensembl:ENST00000409587.5(transcript)|ensembl:ENST00000409735.9(transcript)|ensembl:ENST00000700616.1(transcript)|ensembl:ENST00000700619.1(transcript)|ensembl:ENST00000700620.1(transcript)|ensembl:ENST00000700621.1(transcript)|ensembl:ENST00000700623.1(transcript)|ensembl:ENST00000700625.1(transcript)|ensembl:ENST00000700626.1(transcript)|ensembl:ENST00000700628.1(transcript)|ensembl:ENST00000700630.1(transcript)|ensembl:ENST00000700631.1(transcript)|ensembl:ENST00000700632.1(transcript)|ensembl:ENST00000700633.1(transcript)|ensembl:ENST00000700634.1(transcript)|ensembl:ENST00000700637.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002376""(immune system process)|go:""GO:0004630""(phospholipase D activity)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0014902""(myotube differentiation)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045145""(single-stranded DNA 5'-3' DNA exonuclease activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1900015""(regulation of cytokine production involved in inflammatory response)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR032803|interpro:IPR050874|mint:Q8IV08|rcsb pdb:8Q1K|rcsb pdb:8Q1X|rcsb pdb:8S86|rcsb pdb:8V5T|reactome:R-HSA-1483148|reactome:R-HSA-2029485|refseq:NP_001026866.1|refseq:NP_001278240.1|refseq:NP_036400.2|refseq:XP_005258761.1|refseq:XP_005258764.1|refseq:XP_005258765.1|refseq:XP_005258766.1|refseq:XP_005258767.1|refseq:XP_006723185.1|refseq:XP_011524994.1|refseq:XP_011524995.1|refseq:XP_016882035.1|refseq:XP_016882036.1|refseq:XP_016882037.1|refseq:XP_016882038.1|panther:PTHR10185(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MRwqe3B9RUzfsl3XKuJqvN5rARo1392	rogid:UAnUtENnwfOxhcqSzMmb7yOlBFI9606	intact-crc:3FDAD13222D9A9EC|rigid:9fmA4zw53zFGU75NjzE05nNL+k0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P07332	uniprotkb:Q81VW3	intact:EBI-1055635|ensembl:ENSP00000331504.3|uniprotkb:B4DUD0|uniprotkb:E9PC94|uniprotkb:E9PC95|uniprotkb:Q2VXS7|uniprotkb:Q2VXS8|uniprotkb:Q2VXT0|uniprotkb:Q6GTU5|uniprotkb:B2R6E6	intact:EBI-2809695|uniprotkb:Q6KYL1|uniprotkb:Q6I4W7	psi-mi:fes_human(display_long)|uniprotkb:FES(gene name)|psi-mi:FES(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:Proto-oncogene c-Fes(gene name synonym)|uniprotkb:Proto-oncogene c-Fps(gene name synonym)|uniprotkb:Feline sarcoma/Fujinami avian sarcoma oncogene homolog(gene name synonym)|uniprotkb:p93c-fes(gene name synonym)	psi-mi:syk_bacan(display_long)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:BAS0076(locus name)|uniprotkb:BA_0076(locus name)|uniprotkb:GBAA_0076(locus name)|uniprotkb:lysS(gene name)|psi-mi:lysS(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809692|imex:IM-13779-1389	author score:15|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000182511.12(gene)|ensembl:ENST00000328850.8(transcript)|go:""GO:0001578""(microtubule bundle formation)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006935""(chemotaxis)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007155""(cell adhesion)|go:""GO:0008017""(microtubule binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0043304""(regulation of mast cell degranulation)|go:""GO:0045595""(regulation of cell differentiation)|go:""GO:0045639""(positive regulation of myeloid cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0051450""(myoblast proliferation)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0071305""(cellular response to vitamin D)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016250(Tyrosine-protein kinase, Fes/Fps)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027267|interpro:IPR031160|interpro:IPR035849|interpro:IPR036860|interpro:IPR050198|mint:P07332|rcsb pdb:1WQU|rcsb pdb:2DCR|rcsb pdb:3BKB|rcsb pdb:3CBL|rcsb pdb:3CD3|rcsb pdb:4DYL|rcsb pdb:4E93|rcsb pdb:6JMF|rcsb pdb:7T1K|rcsb pdb:7T1L|rcsb pdb:8X2T|reactome:R-HSA-1433557|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|refseq:NP_001137255.1|refseq:NP_001137256.1|refseq:NP_001137257.1|refseq:NP_001996.1|refseq:XP_005254937.1|refseq:XP_005254939.1|refseq:XP_016877494.1|refseq:XP_016877495.1|refseq:XP_016877496.1|refseq:XP_016877497.1|refseq:XP_016877498.1|refseq:XP_016877499.1|panther:PTHR24418(orthology-group)"	"interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|refseq:WP_000369671.1|go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|go:""GO:0016740""(transferase activity)|interpro:IPR034762|interpro:IPR044136|refseq:NP_842645.1|refseq:YP_026363.1|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jsI2Ytqu7whZlUt7qISAW3W3WqQ9606	rogid:cj4MS8ifiK7Z2KbRGFGgXrn3x941392	intact-crc:0D180C741E4C365D|rigid:HEsJtY5U+45/yYhVi84aZ9JRXMk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P1I7	uniprotkb:P41222	intact:EBI-2809746|uniprotkb:Q6KXV0|uniprotkb:Q6I440|uniprotkb:E9RCC7|uniprotkb:E9RCC8|uniprotkb:A0A2P0H989|uniprotkb:Q81Z98	intact:EBI-948821|uniprotkb:Q9UC22|uniprotkb:Q5SQ10|uniprotkb:Q7M4P3|uniprotkb:Q9UCC9|uniprotkb:Q9UCD9|uniprotkb:B2R727|ensembl:ENSP00000360687.3	psi-mi:a0a6l8p1i7_bacan(display_long)|uniprotkb:GBAA_0374(locus name)	psi-mi:ptgds_human(display_long)|uniprotkb:Lipocalin-type prostaglandin-D synthase(gene name synonym)|uniprotkb:Glutathione-independent PGD synthase(gene name synonym)|uniprotkb:Prostaglandin-D2 synthase(gene name synonym)|uniprotkb:Beta-trace protein(gene name synonym)|uniprotkb:Cerebrin-28(gene name synonym)|uniprotkb:PTGDS(gene name)|psi-mi:PTGDS(display_short)|uniprotkb:PDS(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809743|imex:IM-13779-1393	author score:14|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017501(Phage infection protein, YhgE,  C-terminal)|interpro:IPR017500(Phage infection protein, YhgE,  N-terminal)|interpro:IPR051328|go:""GO:0016020""(membrane)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR013525(ABC-2 type transporter)|refseq:WP_000810134.1"	"refseq:NP_000945.3|ensembl:ENSG00000107317.13(gene)|ensembl:ENST00000371625.8(transcript)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0004667""(prostaglandin-D synthase activity)|go:""GO:0005501""(retinoid binding)|go:""GO:0005504""(fatty acid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0010467""(gene expression)|go:""GO:0019371""(cyclooxygenase pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043303""(mast cell degranulation)|go:""GO:0045187""(regulation of circadian sleep/wake cycle, sleep)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000255""(negative regulation of male germ cell proliferation)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002345(Lipocalin)|interpro:IPR012674(Calycin)|interpro:IPR022272|mint:P41222|rcsb pdb:2WWP|rcsb pdb:3O19|rcsb pdb:3O22|rcsb pdb:3O2Y|rcsb pdb:4IMN|rcsb pdb:4IMO|rcsb pdb:4ORR|rcsb pdb:4ORS|rcsb pdb:4ORU|rcsb pdb:4ORW|rcsb pdb:4ORX|rcsb pdb:4ORY|rcsb pdb:4OS0|rcsb pdb:4OS3|rcsb pdb:4OS8|rcsb pdb:5WY9|rcsb pdb:8HTA|reactome:R-HSA-2162123|reactome:R-HSA-9690406|panther:PTHR11430(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Km4jDuu44pVTrI8b6www/dkgkrY1392	rogid:hqvCVc1a1AWLCZWiYWgA4vPZNtk9606	intact-crc:372F2D67ED62B60D|rigid:VX4H8091vg3qMawTStGaxZsjsTA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P1C8	uniprotkb:Q9Y3C5	intact:EBI-2809717|uniprotkb:Q6KX13|uniprotkb:Q6I395|uniprotkb:E9QX61|uniprotkb:E9QX62|uniprotkb:Q81V12|uniprotkb:A0A0J1HPE8	intact:EBI-396669|intact:EBI-2129167|uniprotkb:A8KAI2|uniprotkb:Q5T7R8|ensembl:ENSP00000242719.3	psi-mi:a0a6l8p1c8_bacan(display_long)|uniprotkb:GBAA_0692(locus name)	psi-mi:rnf11_human(display_long)|uniprotkb:CGI-123(orf name)|uniprotkb:RNF11(gene name)|psi-mi:RNF11(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809722|imex:IM-13779-1392	author score:14|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000791491.1|interpro:IPR029062|interpro:IPR039975	"refseq:NP_055187.1|ensembl:ENSG00000123091.5(gene)|ensembl:ENST00000242719.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005769""(early endosome)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0055037""(recycling endosome)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042981|interpro:IPR052804|mint:Q9Y3C5|panther:PTHR46359(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rmCdN8WfYRTzGdoiaYY3DCxiNa01392	rogid:Uj0YAf/t+AdYbMd6fgQ8hVKoP0w9606	intact-crc:0F446338D8CA8088|rigid:y6hfDO7xfQNgWiG5tSgSE5W7dRU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3ACA2	uniprotkb:P20339	intact:EBI-2809732|uniprotkb:Q6I4Z1|uniprotkb:Q6KYN5|uniprotkb:E9R6Z1|uniprotkb:E9R6Z2|uniprotkb:A0A2P0H8Q3|uniprotkb:Q81VY7	intact:EBI-399437|uniprotkb:B4DJA5|intact:EBI-1048179|uniprotkb:Q6FI44|ensembl:ENSP00000273047.4	psi-mi:a0a6h3aca2_bacan(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:GBAA_0052(locus name)	psi-mi:rab5a_human(display_long)|uniprotkb:RAB5A(gene name)|psi-mi:RAB5A(display_short)|uniprotkb:RAB5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809729|imex:IM-13779-1391	author score:14|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003711(Transcription factor CarD)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR027417|go:""GO:0000716""(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016787""(hydrolase activity)|refseq:WP_000579702.1|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|interpro:IPR047112"	"refseq:NP_004153.2|panther:PTHR24073(orthology-group)|refseq:NP_001278977.1|ensembl:ENSG00000144566.11(gene)|ensembl:ENST00000273047.9(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006909""(phagocytosis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0010008""(endosome membrane)|go:""GO:0012505""(endomembrane system)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0019003""(GDP binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032009""(early phagosome)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0036477""(somatodendritic compartment)|go:""GO:0042470""(melanosome)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043195""(terminal bouton)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043679""(axon terminus)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045121""(membrane raft)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0051036""(regulation of endosome size)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098559""(cytoplasmic side of early endosome membrane)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P20339|rcsb pdb:1N6H|rcsb pdb:1N6I|rcsb pdb:1N6K|rcsb pdb:1N6L|rcsb pdb:1N6N|rcsb pdb:1N6O|rcsb pdb:1N6P|rcsb pdb:1N6R|rcsb pdb:1R2Q|rcsb pdb:1TU3|rcsb pdb:1TU4|rcsb pdb:3MJH|rcsb pdb:4Q9U|rcsb pdb:7BL1|reactome:R-HSA-1660499|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9636383|reactome:R-HSA-9820960|reactome:R-HSA-983231|dip:DIP-380N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:YI7l8CaJx4h5svtxw/Ch5kofxR81392	rogid:SgowwV7QSVCvfsqSDE+6CHmPmKA9606	intact-crc:DFD6A409DEBE2F11|rigid:Uy2kV4YdengGOyT3UArJR5mg2Ug	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P1Z2	uniprotkb:A0A6L8PKS7	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960.1	intact:EBI-2809705|uniprotkb:Q6HR58|uniprotkb:Q6KKH5|uniprotkb:E9QWF2|uniprotkb:E9QWF3|uniprotkb:A0A2P0HL14|uniprotkb:Q81XC3	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:a0a6l8pks7_bacan(display_long)|uniprotkb:GBAA_5317(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809710|imex:IM-13779-1390	author score:15|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137154.1|refseq:NP_065949.1|ensembl:ENSG00000012822.16(gene)|ensembl:ENST00000550804.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030518""(nuclear receptor-mediated steroid hormone signaling pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|interpro:IPR051002|mint:Q9P1Z2|refseq:XP_016875196.1|dip:DIP-47322N|panther:PTHR31915(orthology-group)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR051310|interpro:IPR025278|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|refseq:WP_000455036.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	rogid:LEAQuRzrOsJwYgZq7QXDmoKrfqM1392	intact-crc:3F772CB6108D5576|rigid:+FBcvRi+u01sxMvA7/jR2Ja0hsQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7RE19	uniprotkb:P19838	intact:EBI-2809783|uniprotkb:Q6KPM6|uniprotkb:Q6HVF7|uniprotkb:E9QS28|uniprotkb:E9QS29|uniprotkb:Q81Y62	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a0f7re19_bacan(display_long)|uniprotkb:GBAA_3695(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809780|imex:IM-13779-1395	author score:13|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001119(S-layer homology region)|interpro:IPR051465|go:""GO:0030115""(S-layer)|interpro:IPR032247"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:RZeq/OQN8n8nnEe280+/uO/FFX01392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:3EE2CB4F1999EF26|rigid:tBHKLSXQvtl/gwfEcpLg4IBmPlk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3K3	uniprotkb:Q81ST3	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	intact:EBI-2809767|uniprotkb:Q6I113|uniprotkb:Q6KUW7	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:panb_bacan(display_long)|uniprotkb:panB(gene name)|psi-mi:panB(display_short)|uniprotkb:Ketopantoate hydroxymethyltransferase(gene name synonym)|uniprotkb:BA_1562(locus name)|uniprotkb:GBAA_1562(locus name)|uniprotkb:BAS1449(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809773|imex:IM-13779-1396	author score:13|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"interpro:IPR003700(Ketopantoate hydroxymethyltransferase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|refseq:WP_000851103.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003864""(3-methyl-2-oxobutanoate hydroxymethyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0015940""(pantothenate biosynthetic process)|interpro:IPR040442|refseq:NP_844012.1|refseq:YP_027718.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:cq+jbW/VKpc3K0Otc+9f0LBhIIk1392	intact-crc:A792E9BBF6A9F207|rigid:Vn2umu+YuTdzVhoHZrjM4dPCl6E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P38507	uniprotkb:P01857-1	intact:EBI-7840885|intact:MINT-1505339	intact:EBI-42826219|ensembl:ENSP00000374991.2|ensembl:ENSP00000488387.1	psi-mi:spa_staau(display_long)|uniprotkb:spa(gene name)|psi-mi:spa(display_short)|uniprotkb:Staphylococcal protein A(gene name synonym)	psi-mi:p01857-1(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)|uniprotkb:Secreted(isoform synonym)|uniprotkb:sIgG1(isoform synonym)	"psi-mi:""MI:0018""(two hybrid)"	Fukuda et al. (2010)	pubmed:20214683|imex:IM-15677|mint:MINT-7556261|mint:fj-09-1428	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-7840879|mint:MINT-7556266|imex:IM-15677-1	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:5CBN|go:""GO:0005576""(extracellular region)|go:""GO:0019864""(IgG binding)|rcsb pdb:1BDC|rcsb pdb:1BDD|rcsb pdb:1EDI|rcsb pdb:1EDJ|rcsb pdb:1EDK|rcsb pdb:1EDL|rcsb pdb:1FC2|rcsb pdb:1H0T|rcsb pdb:1LP1|rcsb pdb:1Q2N|rcsb pdb:1SS1|rcsb pdb:2JWD|rcsb pdb:2M5A|rcsb pdb:2SPZ|rcsb pdb:3MZW|rcsb pdb:4NPD|rcsb pdb:4NPE|rcsb pdb:4NPF|rcsb pdb:4WWI|rcsb pdb:4Y4Y|rcsb pdb:4Y5Z|rcsb pdb:4ZMD|rcsb pdb:4ZNC|rcsb pdb:5CBO|rcsb pdb:5COC|rcsb pdb:5EWX|rcsb pdb:5H76|rcsb pdb:5H79|rcsb pdb:5H7A|rcsb pdb:5H7B|rcsb pdb:5H7C|rcsb pdb:5H7D|rcsb pdb:5X3F|rcsb pdb:5XBY|rcsb pdb:6KRV|rcsb pdb:7EOY|rcsb pdb:7EP6|rcsb pdb:7FDJ|rcsb pdb:7NHA|rcsb pdb:7NHC|rcsb pdb:7NHX|rcsb pdb:7NI0|rcsb pdb:7NIK|rcsb pdb:7NIL|rcsb pdb:7NIR|rcsb pdb:7NIS|rcsb pdb:7NJ3|rcsb pdb:7NJ4|rcsb pdb:7NJ5|rcsb pdb:7NJ7|rcsb pdb:7NK1|rcsb pdb:7NK2|rcsb pdb:8CPL|interpro:IPR009063(Immunoglobulin/albumin-binding)|interpro:IPR018392|interpro:IPR003132(Protein A, Ig-binding)|interpro:IPR005038(Octapeptide repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|refseq:WP_047211818.1|mint:P38507|interpro:IPR036779|interpro:IPR019931|mint:MINT-7556268(identity)"	ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390549.6(transcript)|ensembl:ENST00000631466.1(transcript)|intact:EBI-356114(isoform-parent)|mint:MINT-7556269(identity)	-	comment:mint	-	figure legend:F2|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2010/01/27	2025/03/31	rogid:WV65RLWVR/JIZobtCyKqyeQsjpc1280	rogid:1YK8rrTDnOYYKW5wHI48/rYlr5o9606	intact-crc:2C6CC7821196584F|rigid:HpnUNH56/khorTaVyE4acZp0p3Y	false	binding-associated region:212-269(MINT-7556273)|mutation decreasing interaction:246-246(MINT-7556284)|fusion protein:?-?(MINT-7556270)	fusion protein:?-?(MINT-7556276)|binding-associated region:119-330(MINT-7556279)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q04206	uniprotkb:B7UNX4	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	intact:EBI-8520963|intact:MINT-8094579	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:b7unx4_eco27(display_long)|uniprotkb:E2348C_1042(locus name)	"psi-mi:""MI:0435""(protease assay)"	Baruch et al. (2011)	mint:MINT-8094283|pubmed:21113130|imex:IM-15327|doi:10.1038/emboj.2010.297	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8520958|mint:MINT-8094297|imex:IM-15327-1	intact-miscore:0.44	-	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3|mint:MINT-8094300(identity)"	interpro:IPR025208|mint:B7UNX4|mint:MINT-8094299(identity)	-	-	comment:mint	figure legend:f5d|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/02/14	2025/03/26	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rogid:yDxmgZLbXZhvASDg97uc2EDjwjY574521	intact-crc:1D6E5A7FABB2ADC9|rigid:hrThXZStf5apiQANq8KosQz5wWk	false	binding-associated region:1-210(MINT-8094586)	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:B5BUJ7	intact:EBI-8520980	intact:EBI-8520993|intact:MINT-8094526	intact:MINT-8094291	psi-mi:b5buj7_human(display_long)|uniprotkb:MAPK9(gene name)|psi-mi:MAPK9(display_short)	psi-mi:d3qni8_ecocb(display_short)|psi-mi:EBI-8520980(display_long)|uniprotkb:nleD(gene name)|psi-mi:nleD(display_short)|uniprotkb:G2583_1000(locus name)	"psi-mi:""MI:0435""(protease assay)"	Baruch et al. (2011)	mint:MINT-8094283|pubmed:21113130|imex:IM-15327|doi:10.1038/emboj.2010.297	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:701177(ecocb)|taxid:701177(""Escherichia coli O55:H7 (strain CB9615 / EPEC)"")"	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8520988|mint:MINT-8094544|imex:IM-15327-2	intact-miscore:0.44	-	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008351(JNK MAP kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|mint:B5BUJ7|go:""GO:0004705""(JUN kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0033554""(cellular response to stress)|go:""GO:0048511""(rhythmic process)|go:""GO:0106310""(protein serine kinase activity)|interpro:IPR050117|mint:MINT-8094548(identity)"	uniprotkb:D3QNI8(uniprot-removed-ac)|mint:MINT-8094546(identity)	-	comment:mint	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint	figure legend:f2d|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/02/14	2025/03/31	rogid:FgJiImWX3Q1jcZv7Sknue389gZc9606	rogid:bhJER/V4yZaFTHf+smMrT0Ldjig701177	intact-crc:A03A314945D89427|rigid:ogdlvK5l1+qzFdwZ1cwDD1Iz+vE	false	his tag:?-?(MINT-8094556)	mutation disrupting interaction:143-143(MINT-8094552)	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
intact:EBI-8520980	uniprotkb:B5BUJ7	intact:MINT-8094291	intact:EBI-8520993|intact:MINT-8094526	psi-mi:d3qni8_ecocb(display_short)|psi-mi:EBI-8520980(display_long)|uniprotkb:nleD(gene name)|psi-mi:nleD(display_short)|uniprotkb:G2583_1000(locus name)	psi-mi:b5buj7_human(display_long)|uniprotkb:MAPK9(gene name)|psi-mi:MAPK9(display_short)	"psi-mi:""MI:0435""(protease assay)"	Baruch et al. (2011)	mint:MINT-8094283|pubmed:21113130|imex:IM-15327|doi:10.1038/emboj.2010.297	"taxid:701177(ecocb)|taxid:701177(""Escherichia coli O55:H7 (strain CB9615 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8521022|mint:MINT-8094560|imex:IM-15327-3	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:D3QNI8(uniprot-removed-ac)|mint:MINT-8094562(identity)	"interpro:IPR008351(JNK MAP kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|mint:B5BUJ7|go:""GO:0004705""(JUN kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0033554""(cellular response to stress)|go:""GO:0048511""(rhythmic process)|go:""GO:0106310""(protein serine kinase activity)|interpro:IPR050117|mint:MINT-8094564(identity)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint	comment:mint	comment:mint|figure legend:f1g f2e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/02/14	2025/03/31	rogid:bhJER/V4yZaFTHf+smMrT0Ldjig701177	rogid:FgJiImWX3Q1jcZv7Sknue389gZc9606	intact-crc:E9417420E6AD600B|rigid:ogdlvK5l1+qzFdwZ1cwDD1Iz+vE	false	-	his tag:?-?(MINT-8094568)	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:P0A6F9	uniprotkb:Q16762	intact:EBI-369169|uniprotkb:P05380|uniprotkb:Q2M6G2	intact:EBI-8463774|intact:UNK-5474760|uniprotkb:B3KRM1|intact:UNK-5393841|uniprotkb:Q6IB06|ensembl:ENSP00000249042.3|ensembl:ENSP00000385828.3|ensembl:ENSP00000478739.1	psi-mi:ch10_ecoli(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:mopB(gene name synonym)|uniprotkb:JW4102(locus name)|uniprotkb:b4142(locus name)	psi-mi:thtr_human(display_long)|uniprotkb:TST(gene name)|psi-mi:TST(display_short)|uniprotkb:Rhodanese(gene name synonym)	"psi-mi:""MI:0051""(fluorescence technology)"	Motojima et al. (2010)	pubmed:20959808|imex:IM-15404|mint:MINT-8088424|doi:10.1038/emboj.2010.262	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8463768|mint:MINT-8088432|imex:IM-15404-5	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_418566.1|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0009408""(response to heat)|go:""GO:0019068""(virion assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:1990220""(GroEL-GroES complex)|interpro:IPR011032(GroES-like)|interpro:IPR018369|interpro:IPR020818|interpro:IPR037124|rcsb pdb:1AON|rcsb pdb:1EGS|rcsb pdb:1GRU|rcsb pdb:1PCQ|rcsb pdb:1PF9|rcsb pdb:1SVT|rcsb pdb:1SX4|rcsb pdb:2C7C|rcsb pdb:2C7D|rcsb pdb:3WVL|rcsb pdb:3ZPZ|rcsb pdb:3ZQ0|rcsb pdb:3ZQ1|rcsb pdb:5OPX|rcsb pdb:7PBJ|rcsb pdb:7PBX|rcsb pdb:7VWX|rcsb pdb:8BA9|rcsb pdb:8BKZ|rcsb pdb:8BM0|rcsb pdb:8BM1|rcsb pdb:8BMO|rcsb pdb:8BMT|rcsb pdb:8P4M|rcsb pdb:8P4N|rcsb pdb:8P4O|rcsb pdb:8QXS|rcsb pdb:8QXT|rcsb pdb:8QXU|rcsb pdb:8QXV|refseq:WP_001026276.1|mint:P0A6F9|dip:DIP-9835N|panther:PTHR10772(orthology-group)|mint:MINT-8088435(identity)"	"refseq:NP_001257412.1|refseq:NP_003303.2|ensembl:ENSG00000128311.14(gene)|ensembl:ENST00000249042.8(transcript)|ensembl:ENST00000403892.7(transcript)|ensembl:ENST00000622841.1(transcript)|go:""GO:0000098""(sulfur amino acid catabolic process)|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0008097""(5S rRNA binding)|go:""GO:0009440""(cyanate catabolic process)|go:""GO:0016784""(3-mercaptopyruvate sulfurtransferase activity)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0035928""(rRNA import into mitochondrion)|go:""GO:0051029""(rRNA transport)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|interpro:IPR045078|mint:Q16762|rcsb pdb:8AGF|reactome:R-HSA-1614517|reactome:R-HSA-1614558|panther:PTHR11364(orthology-group)|mint:MINT-8088434(identity)"	-	crc64:76829E09B11217EF	"comment:mint|function:""\""Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity\"""""	figure legend:f1|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/02/01	2025/03/26	rogid:mvrAHLYJAZprWGPuKThDXdD66OI83333	rogid:ZFzo21gbhPkIzH5aCGHRS1UoC0Y9606	intact-crc:2C582F06E8223DD8|rigid:rvk9026D2HbtbWVKuqMDMQLE7kI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P0A6F5	uniprotkb:Q16762	intact:EBI-543750|uniprotkb:P06139|uniprotkb:Q2M6G1	intact:EBI-8463774|intact:UNK-5474760|uniprotkb:B3KRM1|intact:UNK-5393841|uniprotkb:Q6IB06|ensembl:ENSP00000249042.3|ensembl:ENSP00000385828.3|ensembl:ENSP00000478739.1	psi-mi:ch60_ecoli(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:GroEL protein(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:mopA(gene name synonym)|uniprotkb:JW4103(locus name)|uniprotkb:b4143(locus name)	psi-mi:thtr_human(display_long)|uniprotkb:TST(gene name)|psi-mi:TST(display_short)|uniprotkb:Rhodanese(gene name synonym)	"psi-mi:""MI:0030""(cross-linking study)"	Motojima et al. (2010)	pubmed:20959808|imex:IM-15404|mint:MINT-8088424|doi:10.1038/emboj.2010.262	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8464022|mint:MINT-8090147|imex:IM-15404-4	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_418567.1|refseq:WP_000729117.1|mint:P0A6F5|dip:DIP-339N|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0009314""(response to radiation)|go:""GO:0009408""(response to heat)|go:""GO:0016020""(membrane)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019068""(virion assembly)|go:""GO:0042026""(protein refolding)|go:""GO:0042802""(identical protein binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990220""(GroEL-GroES complex)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:1AON|rcsb pdb:1DK7|rcsb pdb:1DKD|rcsb pdb:1FY9|rcsb pdb:1FYA|rcsb pdb:1GR5|rcsb pdb:1GRL|rcsb pdb:1GRU|rcsb pdb:1JON|rcsb pdb:1KID|rcsb pdb:1KP8|rcsb pdb:1LA1|rcsb pdb:1MNF|rcsb pdb:1OEL|rcsb pdb:1PCQ|rcsb pdb:1PF9|rcsb pdb:1SS8|rcsb pdb:1SVT|rcsb pdb:1SX3|rcsb pdb:1SX4|rcsb pdb:1XCK|rcsb pdb:2C7C|rcsb pdb:2C7D|rcsb pdb:2C7E|rcsb pdb:2CGT|rcsb pdb:2EU1|rcsb pdb:2NWC|rcsb pdb:2YEY|rcsb pdb:3C9V|rcsb pdb:3CAU|rcsb pdb:3VZ6|rcsb pdb:3VZ7|rcsb pdb:3VZ8|rcsb pdb:3WVL|rcsb pdb:3ZPZ|rcsb pdb:3ZQ0|rcsb pdb:3ZQ1|rcsb pdb:4AAQ|rcsb pdb:4AAR|rcsb pdb:4AAS|rcsb pdb:4AAU|rcsb pdb:4AB2|rcsb pdb:4AB3|rcsb pdb:4V43|rcsb pdb:4WGL|rcsb pdb:4WSC|rcsb pdb:5OPW|rcsb pdb:5OPX|rcsb pdb:5W0S|rcsb pdb:7PBJ|rcsb pdb:7PBX|rcsb pdb:7VWX|rcsb pdb:7XOJ|rcsb pdb:7XOK|rcsb pdb:7XOL|rcsb pdb:7XOM|rcsb pdb:7XON|rcsb pdb:7XOO|rcsb pdb:7XOP|rcsb pdb:7XOQ|rcsb pdb:7XOR|rcsb pdb:7XOS|rcsb pdb:7YWY|rcsb pdb:8BA7|rcsb pdb:8BA8|rcsb pdb:8BA9|rcsb pdb:8BKZ|rcsb pdb:8BL2|rcsb pdb:8BL7|rcsb pdb:8BLC|rcsb pdb:8BLD|rcsb pdb:8BLE|rcsb pdb:8BLF|rcsb pdb:8BLY|rcsb pdb:8BM0|rcsb pdb:8BM1|rcsb pdb:8BMD|rcsb pdb:8BMO|rcsb pdb:8BMT|rcsb pdb:8P4M|rcsb pdb:8P4N|rcsb pdb:8P4O|rcsb pdb:8QXS|rcsb pdb:8QXT|rcsb pdb:8QXU|rcsb pdb:8QXV|rcsb pdb:8S32|panther:PTHR45633(orthology-group)|mint:MINT-8090153(identity)"	"refseq:NP_001257412.1|refseq:NP_003303.2|ensembl:ENSG00000128311.14(gene)|ensembl:ENST00000249042.8(transcript)|ensembl:ENST00000403892.7(transcript)|ensembl:ENST00000622841.1(transcript)|go:""GO:0000098""(sulfur amino acid catabolic process)|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0008097""(5S rRNA binding)|go:""GO:0009440""(cyanate catabolic process)|go:""GO:0016784""(3-mercaptopyruvate sulfurtransferase activity)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0035928""(rRNA import into mitochondrion)|go:""GO:0051029""(rRNA transport)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|interpro:IPR045078|mint:Q16762|rcsb pdb:8AGF|reactome:R-HSA-1614517|reactome:R-HSA-1614558|panther:PTHR11364(orthology-group)|mint:MINT-8090149(identity)"	-	crc64:CD3A0FB505F74AD1	"comment:mint|function:""\""Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity\"""""	figure legend:f3b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/02/01	2025/03/26	rogid:TuNoPwyx7V5IaOQVjtdcc6sctqw83333	rogid:ZFzo21gbhPkIzH5aCGHRS1UoC0Y9606	intact-crc:02B0BC1C8CBE2976|rigid:yIGHdsJspO9Aj/uGmsMjkqtLXj0	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P0A6F9	uniprotkb:Q16762	intact:EBI-369169|uniprotkb:P05380|uniprotkb:Q2M6G2	intact:EBI-8463774|intact:UNK-5474760|uniprotkb:B3KRM1|intact:UNK-5393841|uniprotkb:Q6IB06|ensembl:ENSP00000249042.3|ensembl:ENSP00000385828.3|ensembl:ENSP00000478739.1	psi-mi:ch10_ecoli(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:mopB(gene name synonym)|uniprotkb:JW4102(locus name)|uniprotkb:b4142(locus name)	psi-mi:thtr_human(display_long)|uniprotkb:TST(gene name)|psi-mi:TST(display_short)|uniprotkb:Rhodanese(gene name synonym)	"psi-mi:""MI:0071""(molecular sieving)"	Motojima et al. (2010)	pubmed:20959808|imex:IM-15404|mint:MINT-8088424|doi:10.1038/emboj.2010.262	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8464052|mint:MINT-8090118|imex:IM-15404-1	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_418566.1|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0009408""(response to heat)|go:""GO:0019068""(virion assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:1990220""(GroEL-GroES complex)|interpro:IPR011032(GroES-like)|interpro:IPR018369|interpro:IPR020818|interpro:IPR037124|rcsb pdb:1AON|rcsb pdb:1EGS|rcsb pdb:1GRU|rcsb pdb:1PCQ|rcsb pdb:1PF9|rcsb pdb:1SVT|rcsb pdb:1SX4|rcsb pdb:2C7C|rcsb pdb:2C7D|rcsb pdb:3WVL|rcsb pdb:3ZPZ|rcsb pdb:3ZQ0|rcsb pdb:3ZQ1|rcsb pdb:5OPX|rcsb pdb:7PBJ|rcsb pdb:7PBX|rcsb pdb:7VWX|rcsb pdb:8BA9|rcsb pdb:8BKZ|rcsb pdb:8BM0|rcsb pdb:8BM1|rcsb pdb:8BMO|rcsb pdb:8BMT|rcsb pdb:8P4M|rcsb pdb:8P4N|rcsb pdb:8P4O|rcsb pdb:8QXS|rcsb pdb:8QXT|rcsb pdb:8QXU|rcsb pdb:8QXV|refseq:WP_001026276.1|mint:P0A6F9|dip:DIP-9835N|panther:PTHR10772(orthology-group)|mint:MINT-8090122(identity)"	"refseq:NP_001257412.1|refseq:NP_003303.2|ensembl:ENSG00000128311.14(gene)|ensembl:ENST00000249042.8(transcript)|ensembl:ENST00000403892.7(transcript)|ensembl:ENST00000622841.1(transcript)|go:""GO:0000098""(sulfur amino acid catabolic process)|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0008097""(5S rRNA binding)|go:""GO:0009440""(cyanate catabolic process)|go:""GO:0016784""(3-mercaptopyruvate sulfurtransferase activity)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0035928""(rRNA import into mitochondrion)|go:""GO:0051029""(rRNA transport)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|interpro:IPR045078|mint:Q16762|rcsb pdb:8AGF|reactome:R-HSA-1614517|reactome:R-HSA-1614558|panther:PTHR11364(orthology-group)|mint:MINT-8090120(identity)"	-	crc64:76829E09B11217EF	"comment:mint|function:""\""Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity\"""""	figure legend:f1d|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/02/01	2025/03/26	rogid:mvrAHLYJAZprWGPuKThDXdD66OI83333	rogid:ZFzo21gbhPkIzH5aCGHRS1UoC0Y9606	intact-crc:225F1643712599F3|rigid:rvk9026D2HbtbWVKuqMDMQLE7kI	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P01031	uniprotkb:D3JIB2	intact:EBI-8558308|ensembl:ENSP00000223642.1|intact:UNK-5392818|uniprotkb:Q27I61|intact:UNK-5368655|uniprotkb:Q14CJ0|intact:UNK-5396112	intact:EBI-8558292|intact:MINT-8143387	psi-mi:co5_human(display_long)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4(gene name synonym)|uniprotkb:CPAMD4(gene name synonym)|uniprotkb:C5(gene name)|psi-mi:C5(display_short)	psi-mi:d3jib2_staau(display_long)	"psi-mi:""MI:0114""(x-ray crystallography)"	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8558286|mint:MINT-8143400|imex:IM-15401-3	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106804.10(gene)|ensembl:ENST00000223642.3(transcript)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005579""(membrane attack complex)|go:""GO:0005615""(extracellular space)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008009""(chemokine activity)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010760""(negative regulation of macrophage chemotaxis)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|interpro:IPR048843|interpro:IPR050473|mint:P01031|rcsb pdb:1CFA|rcsb pdb:1KJS|rcsb pdb:1XWE|rcsb pdb:3CU7|rcsb pdb:3HQA|rcsb pdb:3HQB|rcsb pdb:3KLS|rcsb pdb:3KM9|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:4A5W|rcsb pdb:4E0S|rcsb pdb:4P39|rcsb pdb:4UU9|rcsb pdb:5B4P|rcsb pdb:5B71|rcsb pdb:5HCC|rcsb pdb:5HCD|rcsb pdb:5HCE|rcsb pdb:5I5K|rcsb pdb:6H03|rcsb pdb:6H04|rcsb pdb:6RPT|rcsb pdb:6RQJ|rcsb pdb:7AD6|rcsb pdb:7AD7|rcsb pdb:7NYC|rcsb pdb:7NYD|rcsb pdb:7Y64|rcsb pdb:8B0F|rcsb pdb:8B0G|rcsb pdb:8B0H|rcsb pdb:8HK5|rcsb pdb:8HQC|rcsb pdb:8IA2|rcsb pdb:8JZZ|reactome:R-HSA-166665|reactome:R-HSA-174577|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-977606|refseq:NP_001304092.1|refseq:NP_001726.2|efo:""Orphanet:169150""|panther:PTHR11412(orthology-group)|mint:MINT-8143402(identity)"	"go:""GO:0005576""(extracellular region)|rcsb pdb:3PRX|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|mint:D3JIB2|mint:MINT-8143404(identity)"	-	"function:Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled|comment:mint|function:""\""Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis)\""""|function:""\""Defects in C5 are the cause of complement C5 deficiency [MIM:609536]. Patients with dysfunction of C5 display a propensity for severe recurrent infections\""""|function:""\""Genetic variation in C5 can be associated with susceptibility to liver fibrosis [MIM:120900]. Liver fibrosis is a common consequence of all chronic liver diseases, irrespective of etiology. Common C5 variants can influence the progression and severity of fibrogenesis\"""""	comment:mint	comment:mint|figure legend:f2 t1 st2 sf7|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/03	2024/11/14	rogid:EpfpW2TQ68YvIqNRfr6uIyA6MUU9606	rogid:JNNLSfjz8rj6W9NL6s18CEfKj2o1280	intact-crc:5758911FD8916419|rigid:a21Vs4qDsz7Wldqyn6CoineFoxg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:D3JIB2	uniprotkb:P01031	intact:EBI-8558292|intact:MINT-8143387	intact:EBI-8558308|ensembl:ENSP00000223642.1|intact:UNK-5392818|uniprotkb:Q27I61|intact:UNK-5368655|uniprotkb:Q14CJ0|intact:UNK-5396112	psi-mi:d3jib2_staau(display_long)	psi-mi:co5_human(display_long)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4(gene name synonym)|uniprotkb:CPAMD4(gene name synonym)|uniprotkb:C5(gene name)|psi-mi:C5(display_short)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8558411|mint:MINT-8143431|imex:IM-15401-1	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|rcsb pdb:3PRX|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|mint:D3JIB2|mint:MINT-8143437(identity)"	"ensembl:ENSG00000106804.10(gene)|ensembl:ENST00000223642.3(transcript)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005579""(membrane attack complex)|go:""GO:0005615""(extracellular space)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008009""(chemokine activity)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010760""(negative regulation of macrophage chemotaxis)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|interpro:IPR048843|interpro:IPR050473|mint:P01031|rcsb pdb:1CFA|rcsb pdb:1KJS|rcsb pdb:1XWE|rcsb pdb:3CU7|rcsb pdb:3HQA|rcsb pdb:3HQB|rcsb pdb:3KLS|rcsb pdb:3KM9|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:4A5W|rcsb pdb:4E0S|rcsb pdb:4P39|rcsb pdb:4UU9|rcsb pdb:5B4P|rcsb pdb:5B71|rcsb pdb:5HCC|rcsb pdb:5HCD|rcsb pdb:5HCE|rcsb pdb:5I5K|rcsb pdb:6H03|rcsb pdb:6H04|rcsb pdb:6RPT|rcsb pdb:6RQJ|rcsb pdb:7AD6|rcsb pdb:7AD7|rcsb pdb:7NYC|rcsb pdb:7NYD|rcsb pdb:7Y64|rcsb pdb:8B0F|rcsb pdb:8B0G|rcsb pdb:8B0H|rcsb pdb:8HK5|rcsb pdb:8HQC|rcsb pdb:8IA2|rcsb pdb:8JZZ|reactome:R-HSA-166665|reactome:R-HSA-174577|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-977606|refseq:NP_001304092.1|refseq:NP_001726.2|efo:""Orphanet:169150""|panther:PTHR11412(orthology-group)|mint:MINT-8143433(identity)"	-	comment:mint	"function:Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled|comment:mint|function:""\""Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis)\""""|function:""\""Defects in C5 are the cause of complement C5 deficiency [MIM:609536]. Patients with dysfunction of C5 display a propensity for severe recurrent infections\""""|function:""\""Genetic variation in C5 can be associated with susceptibility to liver fibrosis [MIM:120900]. Liver fibrosis is a common consequence of all chronic liver diseases, irrespective of etiology. Common C5 variants can influence the progression and severity of fibrogenesis\"""""	comment:mint|figure legend:sf6b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.4x10^-5(molar)	2011/03/03	2024/11/14	rogid:JNNLSfjz8rj6W9NL6s18CEfKj2o1280	rogid:EpfpW2TQ68YvIqNRfr6uIyA6MUU9606	intact-crc:D1B4D0538EF34600|rigid:a21Vs4qDsz7Wldqyn6CoineFoxg	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:D3JIB2	uniprotkb:P01031	intact:EBI-8558292|intact:MINT-8143387	intact:EBI-8558308|ensembl:ENSP00000223642.1|intact:UNK-5392818|uniprotkb:Q27I61|intact:UNK-5368655|uniprotkb:Q14CJ0|intact:UNK-5396112	psi-mi:d3jib2_staau(display_long)	psi-mi:co5_human(display_long)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4(gene name synonym)|uniprotkb:CPAMD4(gene name synonym)|uniprotkb:C5(gene name)|psi-mi:C5(display_short)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8558427|mint:MINT-8143443|imex:IM-15401-2	intact-miscore:0.52	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|rcsb pdb:3PRX|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|mint:D3JIB2|mint:MINT-8143450(identity)"	"ensembl:ENSG00000106804.10(gene)|ensembl:ENST00000223642.3(transcript)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005579""(membrane attack complex)|go:""GO:0005615""(extracellular space)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008009""(chemokine activity)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010760""(negative regulation of macrophage chemotaxis)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|interpro:IPR048843|interpro:IPR050473|mint:P01031|rcsb pdb:1CFA|rcsb pdb:1KJS|rcsb pdb:1XWE|rcsb pdb:3CU7|rcsb pdb:3HQA|rcsb pdb:3HQB|rcsb pdb:3KLS|rcsb pdb:3KM9|rcsb pdb:3PRX|rcsb pdb:3PVM|rcsb pdb:4A5W|rcsb pdb:4E0S|rcsb pdb:4P39|rcsb pdb:4UU9|rcsb pdb:5B4P|rcsb pdb:5B71|rcsb pdb:5HCC|rcsb pdb:5HCD|rcsb pdb:5HCE|rcsb pdb:5I5K|rcsb pdb:6H03|rcsb pdb:6H04|rcsb pdb:6RPT|rcsb pdb:6RQJ|rcsb pdb:7AD6|rcsb pdb:7AD7|rcsb pdb:7NYC|rcsb pdb:7NYD|rcsb pdb:7Y64|rcsb pdb:8B0F|rcsb pdb:8B0G|rcsb pdb:8B0H|rcsb pdb:8HK5|rcsb pdb:8HQC|rcsb pdb:8IA2|rcsb pdb:8JZZ|reactome:R-HSA-166665|reactome:R-HSA-174577|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-977606|refseq:NP_001304092.1|refseq:NP_001726.2|efo:""Orphanet:169150""|panther:PTHR11412(orthology-group)|mint:MINT-8143446(identity)"	-	comment:mint	"function:Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled|comment:mint|function:""\""Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis)\""""|function:""\""Defects in C5 are the cause of complement C5 deficiency [MIM:609536]. Patients with dysfunction of C5 display a propensity for severe recurrent infections\""""|function:""\""Genetic variation in C5 can be associated with susceptibility to liver fibrosis [MIM:120900]. Liver fibrosis is a common consequence of all chronic liver diseases, irrespective of etiology. Common C5 variants can influence the progression and severity of fibrogenesis\"""""	comment:homomint|comment:mint|figure legend:sf6c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.96x10^-5(molar)	2011/03/03	2025/01/26	rogid:JNNLSfjz8rj6W9NL6s18CEfKj2o1280	rogid:EpfpW2TQ68YvIqNRfr6uIyA6MUU9606	intact-crc:DCB3A7CFA63EBBEC|rigid:FCX5N/N3N4UZWhMJO2ofTOfwqok	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:D3JIB2	uniprotkb:P01024	intact:EBI-8558292|intact:MINT-8143387	intact:EBI-905851|uniprotkb:A7E236|ensembl:ENSP00000245907.4	psi-mi:d3jib2_staau(display_long)	psi-mi:co3_human(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)|uniprotkb:CPAMD1(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Laursen et al. (2011)	mint:MINT-8143379|pubmed:21217642|imex:IM-15401|doi:10.1038/emboj.2010.341	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8558427|mint:MINT-8143443|imex:IM-15401-2	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|rcsb pdb:3PRX|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|mint:D3JIB2|mint:MINT-8143450(identity)"	"efo:""Orphanet:280133""|efo:""Orphanet:544472""|ensembl:ENSG00000125730.18(gene)|ensembl:ENST00000245907.11(transcript)|go:""GO:0001798""(positive regulation of type IIa hypersensitivity)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001970""(positive regulation of activation of membrane attack complex)|go:""GO:0002430""(complement receptor mediated signaling pathway)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007165""(signal transduction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0009617""(response to bacterium)|go:""GO:0009986""(cell surface)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010828""(positive regulation of D-glucose transmembrane transport)|go:""GO:0010866""(regulation of triglyceride biosynthetic process)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0016322""(neuron remodeling)|go:""GO:0031715""(C5L2 anaphylatoxin chemotactic receptor binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035846""(oviduct epithelium development)|go:""GO:0042113""(B cell activation)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0097278""(complement-dependent cytotoxicity)|go:""GO:0150062""(complement-mediated synapse pruning)|go:""GO:0150064""(vertebrate eye-specific patterning)|go:""GO:2000427""(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|interpro:IPR047565|interpro:IPR048848|interpro:IPR049466|interpro:IPR050473|mint:P01024|rcsb pdb:1C3D|rcsb pdb:1GHQ|rcsb pdb:1W2S|rcsb pdb:2A73|rcsb pdb:2A74|rcsb pdb:2GOX|rcsb pdb:2I07|rcsb pdb:2ICE|rcsb pdb:2ICF|rcsb pdb:2NOJ|rcsb pdb:2QKI|rcsb pdb:2WII|rcsb pdb:2WIN|rcsb pdb:2WY7|rcsb pdb:2WY8|rcsb pdb:2XQW|rcsb pdb:2XWB|rcsb pdb:2XWJ|rcsb pdb:3D5R|rcsb pdb:3D5S|rcsb pdb:3G6J|rcsb pdb:3L3O|rcsb pdb:3L5N|rcsb pdb:3NMS|rcsb pdb:3OED|rcsb pdb:3OHX|rcsb pdb:3OXU|rcsb pdb:3RJ3|rcsb pdb:3T4A|rcsb pdb:4HW5|rcsb pdb:4HWJ|rcsb pdb:4I6O|rcsb pdb:4M76|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5FO7|rcsb pdb:5FO8|rcsb pdb:5FO9|rcsb pdb:5FOA|rcsb pdb:5FOB|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:6EHG|rcsb pdb:6RMT|rcsb pdb:6RMU|rcsb pdb:6RUR|rcsb pdb:6RUV|rcsb pdb:6S0B|rcsb pdb:6YO6|rcsb pdb:7AKK|rcsb pdb:7BAG|rcsb pdb:7NOZ|rcsb pdb:7PI6|rcsb pdb:7QIV|rcsb pdb:7TV9|rcsb pdb:7UE9|rcsb pdb:7ZGK|rcsb pdb:8ENU|rcsb pdb:8EOK|rcsb pdb:8HK2|rcsb pdb:8I9L|rcsb pdb:8OQ3|rcsb pdb:8OVB|rcsb pdb:8UH2|rcsb pdb:8UIN|reactome:R-HSA-173736|reactome:R-HSA-174577|reactome:R-HSA-198933|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-418594|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9660826|reactome:R-HSA-977606|refseq:NP_000055.2|dip:DIP-35180N|panther:PTHR11412(orthology-group)|mint:MINT-8143448(identity)"	-	comment:mint	-	comment:homomint|comment:mint|figure legend:sf6c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.96x10^-5(molar)	2011/03/03	2025/01/26	rogid:JNNLSfjz8rj6W9NL6s18CEfKj2o1280	rogid:6Axa89cCPpUXFsLnd7sCurZzLYI9606	intact-crc:DCB3A7CFA63EBBEC|rigid:FCX5N/N3N4UZWhMJO2ofTOfwqok	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A0A380PE22	uniprotkb:O76064	intact:EBI-2856011|uniprotkb:A0A0H2W318|uniprotkb:Q74VW4|uniprotkb:Q7CJX4|uniprotkb:A0A384LD58	intact:EBI-373337|uniprotkb:Q53H16|uniprotkb:Q5NKW5|ensembl:ENSP00000362578.4|uniprotkb:A6NN24|uniprotkb:A8MYC0|uniprotkb:B4DPG0	psi-mi:a0a380pe22_yerpe(display_long)|uniprotkb:YPO2801(locus name)	psi-mi:rnf8_human(display_long)|uniprotkb:RNF8(gene name)|psi-mi:RNF8(display_short)|uniprotkb:KIAA0646(gene name synonym)|uniprotkb:RING finger protein 8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF8(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856008|imex:IM-13779-6062	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR018677|refseq:WP_002209756.1|interpro:IPR025513|refseq:YP_002347742.1	"ensembl:ENSG00000112130.17(gene)|refseq:NP_003949.1|refseq:NP_898901.1|ensembl:ENST00000373479.9(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010212""(response to ionizing radiation)|go:""GO:0030496""(midbody)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0035092""(sperm DNA condensation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036297""(interstrand cross-link repair)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0042393""(histone binding)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0045190""(isotype switching)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0051301""(cell division)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:0140861""(DNA repair-dependent chromatin remodeling)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017335(E3 ubiquitin ligase, RNF8)|interpro:IPR017907|mint:O76064|rcsb pdb:2CSW|rcsb pdb:2PIE|rcsb pdb:4AYC|rcsb pdb:4ORH|rcsb pdb:4WHV|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|dip:DIP-31265N|panther:PTHR15067(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dGYO2y8tXuDYlpLIte+D054U4jc632	rogid:nsYlZhRT5wsltOEjHh1l815IphQ9606	intact-crc:EDDF634FC71A29B2|rigid:vWpktwQiT5tN8l9Izm10DfvjPmA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P07998	uniprotkb:Q8D051	intact:EBI-2823523|uniprotkb:D3DS06|uniprotkb:Q6ICS5|uniprotkb:Q9UCB5|uniprotkb:Q1KHR2|uniprotkb:B2R589|uniprotkb:Q9UCB4|uniprotkb:Q16869|uniprotkb:Q16830|ensembl:ENSP00000344193.3|ensembl:ENSP00000381057.4|ensembl:ENSP00000381060.4|ensembl:ENSP00000399493.2	intact:EBI-2856027	psi-mi:rnas1_human(display_long)|uniprotkb:RNASE1(gene name)|psi-mi:RNASE1(display_short)|uniprotkb:RIB1(gene name synonym)|uniprotkb:RNS1(gene name synonym)|uniprotkb:HP-RNase(gene name synonym)|uniprotkb:RIB-1(gene name synonym)|uniprotkb:RNase UpI-1(gene name synonym)|uniprotkb:Ribonuclease 1(gene name synonym)|uniprotkb:Ribonuclease A(gene name synonym)	psi-mi:q8d051_yerpe(display_long)|uniprotkb:y2759(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856030|imex:IM-13779-6064	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002924.1|refseq:NP_937875.1|refseq:NP_937877.1|refseq:NP_937878.1|ensembl:ENSG00000129538.14(gene)|ensembl:ENST00000340900.3(transcript)|ensembl:ENST00000397967.5(transcript)|ensembl:ENST00000397970.4(transcript)|ensembl:ENST00000412779.2(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0004522""(ribonuclease A activity)|go:""GO:0004540""(RNA nuclease activity)|go:""GO:0016829""(lyase activity)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|mint:P07998|rcsb pdb:1DZA|rcsb pdb:1E21|rcsb pdb:1H8X|rcsb pdb:1Z7X|rcsb pdb:2E0J|rcsb pdb:2E0L|rcsb pdb:2E0M|rcsb pdb:2E0O|rcsb pdb:2K11|rcsb pdb:2Q4G|rcsb pdb:3F8G|rcsb pdb:4KXH|reactome:R-HSA-9613829|reactome:R-HSA-9615710|panther:PTHR11437(orthology-group)"	"interpro:IPR050298|interpro:IPR001897(Porin, bacterial type)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR033900|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0046930""(pore complex)|interpro:IPR023614"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pOyV+GmwHrK9ALqklzbSFYxTmu09606	rogid:wY/QWrt/DKI3164kNHTGn3zhlx0632	intact-crc:58BEE3FC2FE732DE|rigid:gaj8jNNNbcBD40fhYXeFKDqCk2E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIQ3	uniprotkb:P07998	intact:EBI-2842473|uniprotkb:Q8CZN8|uniprotkb:Q0WJM5	intact:EBI-2823523|uniprotkb:D3DS06|uniprotkb:Q6ICS5|uniprotkb:Q9UCB5|uniprotkb:Q1KHR2|uniprotkb:B2R589|uniprotkb:Q9UCB4|uniprotkb:Q16869|uniprotkb:Q16830|ensembl:ENSP00000344193.3|ensembl:ENSP00000381057.4|ensembl:ENSP00000381060.4|ensembl:ENSP00000399493.2	psi-mi:deob_yerpe(display_long)|uniprotkb:deoB(gene name)|psi-mi:deoB(display_short)|uniprotkb:Phosphodeoxyribomutase(gene name synonym)|uniprotkb:YPO0439(locus name)|uniprotkb:y3741(locus name)|uniprotkb:YP_3743(locus name)	psi-mi:rnas1_human(display_long)|uniprotkb:RNASE1(gene name)|psi-mi:RNASE1(display_short)|uniprotkb:RIB1(gene name synonym)|uniprotkb:RNS1(gene name synonym)|uniprotkb:HP-RNase(gene name synonym)|uniprotkb:RIB-1(gene name synonym)|uniprotkb:RNase UpI-1(gene name synonym)|uniprotkb:Ribonuclease 1(gene name synonym)|uniprotkb:Ribonuclease A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856037|imex:IM-13779-6063	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR010045(Phosphopentomutase)|interpro:IPR006124(Metalloenzyme)|interpro:IPR024052|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006015""(5-phosphoribose 1-diphosphate biosynthetic process)|go:""GO:0006018""(2-deoxyribose 1-phosphate catabolic process)|go:""GO:0008973""(phosphopentomutase activity)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0043094""(metabolic compound salvage)|refseq:WP_002209216.1|refseq:YP_002345513.1|panther:PTHR21110(orthology-group)"	"refseq:NP_002924.1|refseq:NP_937875.1|refseq:NP_937877.1|refseq:NP_937878.1|ensembl:ENSG00000129538.14(gene)|ensembl:ENST00000340900.3(transcript)|ensembl:ENST00000397967.5(transcript)|ensembl:ENST00000397970.4(transcript)|ensembl:ENST00000412779.2(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0004522""(ribonuclease A activity)|go:""GO:0004540""(RNA nuclease activity)|go:""GO:0016829""(lyase activity)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|mint:P07998|rcsb pdb:1DZA|rcsb pdb:1E21|rcsb pdb:1H8X|rcsb pdb:1Z7X|rcsb pdb:2E0J|rcsb pdb:2E0L|rcsb pdb:2E0M|rcsb pdb:2E0O|rcsb pdb:2K11|rcsb pdb:2Q4G|rcsb pdb:3F8G|rcsb pdb:4KXH|reactome:R-HSA-9613829|reactome:R-HSA-9615710|panther:PTHR11437(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LC8q64MdN91Wk2zrqc1En6sw9gU632	rogid:pOyV+GmwHrK9ALqklzbSFYxTmu09606	intact-crc:9EEEB9422F489042|rigid:MyNL+rhhA+lfb8gGkxnD2FqcJw4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96EP0	uniprotkb:Q7ARD3	intact:EBI-948111|uniprotkb:Q9H5F1|uniprotkb:Q9NWD2|uniprotkb:Q86VI2|uniprotkb:Q8TEI0|uniprotkb:Q96GB4|uniprotkb:Q96NF1|uniprotkb:A0A962|ensembl:ENSP00000315112.6|ensembl:ENSP00000496609.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:rnf31_human(display_long)|uniprotkb:Zinc in-between-RING-finger ubiquitin-associated domain protein(gene name synonym)|uniprotkb:RNF31(gene name)|psi-mi:RNF31(display_short)|uniprotkb:ZIBRA(gene name synonym)|uniprotkb:HOIL-1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF31(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856020|imex:IM-13779-6065	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:6KC5|rcsb pdb:6KC6|rcsb pdb:6SC5|rcsb pdb:6SC6|rcsb pdb:6SC7|rcsb pdb:6SC8|rcsb pdb:6SC9|rcsb pdb:7TV4|rcsb pdb:7UY2|rcsb pdb:7UYJ|rcsb pdb:7UYK|rcsb pdb:7V8F|rcsb pdb:7V8G|rcsb pdb:9AZJ|rcsb pdb:9B0B|rcsb pdb:9B0Z|rcsb pdb:9B12|reactome:R-HSA-5357786|ensembl:ENSG00000092098.18(gene)|ensembl:ENSG00000285152.2(gene)|ensembl:ENST00000324103.11(transcript)|ensembl:ENST00000647495.2(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0036435""(K48-linked polyubiquitin modification-dependent protein binding)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0071797""(LUBAC complex)|go:""GO:0097039""(protein linear polyubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:1904417""(positive regulation of xenophagy)|go:""GO:1990450""(linear polyubiquitin binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018997|interpro:IPR026254|interpro:IPR032065|interpro:IPR036339|interpro:IPR036443|interpro:IPR040641|interpro:IPR041031|interpro:IPR044066|interpro:IPR047539|interpro:IPR047540|interpro:IPR047541|interpro:IPR047542|interpro:IPR047543|mint:Q96EP0|rcsb pdb:2CT7|rcsb pdb:4DBG|rcsb pdb:4JUY|rcsb pdb:4LJO|rcsb pdb:4LJP|rcsb pdb:4LJQ|rcsb pdb:4OWF|rcsb pdb:4OYJ|rcsb pdb:4OYK|rcsb pdb:4P09|rcsb pdb:4P0A|rcsb pdb:4P0B|rcsb pdb:5EDV|rcsb pdb:5LJN|rcsb pdb:5X0W|rcsb pdb:6GZY|reactome:R-HSA-5357905|reactome:R-HSA-5357956|refseq:NP_001297261.1|refseq:NP_060469.4|dip:DIP-44034N|efo:""Orphanet:329173""|panther:PTHR16004(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:5QylozByg2G8/5LnkorkdY5fPec9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:17C2ACDB454D1F8E|rigid:/PLOvn1gDY6xUoARlHeFrwrWQP0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBZ9	uniprotkb:Q9NWF9	intact:EBI-2851065|uniprotkb:Q0WC55	intact:EBI-723313|uniprotkb:Q7Z7C1|uniprotkb:Q6Y691|uniprotkb:Q75ML7|uniprotkb:Q7Z2H7|uniprotkb:Q8NHW7|uniprotkb:Q9NYT1|ensembl:ENSP00000404602.2	psi-mi:dpo4_yerpe(display_long)|uniprotkb:dinP(gene name synonym)|uniprotkb:YPO3231(locus name)|uniprotkb:y0959(locus name)|uniprotkb:YP_0702(locus name)|uniprotkb:dinB(gene name)|psi-mi:dinB(display_short)	psi-mi:rn216_human(display_long)|uniprotkb:TRIAD3(gene name synonym)|uniprotkb:UBCE7IP1(gene name synonym)|uniprotkb:RING finger protein 216(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 1(gene name synonym)|uniprotkb:Zinc finger protein inhibiting NF-kappa-B(gene name synonym)|uniprotkb:Triad domain-containing protein 3(gene name synonym)|uniprotkb:RNF216(gene name)|psi-mi:RNF216(display_short)|uniprotkb:ZIN(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF216(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856044|imex:IM-13779-6066	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR043502|interpro:IPR017961|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR022880|refseq:WP_002208708.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0009432""(SOS response)|go:""GO:0042276""(error-prone translesion synthesis)|interpro:IPR043128|interpro:IPR036775|interpro:IPR053848|refseq:YP_002348133.1|interpro:IPR050116|panther:PTHR11076(orthology-group)"	"ensembl:ENSG00000011275.19(gene)|ensembl:ENST00000425013.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0032648""(regulation of interferon-beta production)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0050691""(regulation of defense response to virus by host)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044066|interpro:IPR047544|interpro:IPR047545|interpro:IPR047546|interpro:IPR051628|mint:Q9NWF9|rcsb pdb:7M4M|rcsb pdb:7M4N|rcsb pdb:7M4O|rcsb pdb:8EB0|reactome:R-HSA-936440|refseq:NP_996994.1|refseq:NP_996999.1|refseq:XP_005249842.1|refseq:XP_011513738.1|refseq:XP_016867852.1|refseq:XP_016867854.1|efo:""Orphanet:1173""|panther:PTHR22770(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dJC1TxxW9BoCSiFaklVosXbx3KY632	rogid:IrD/snISVEoKM7Mej6ufGnrokTc9606	intact-crc:A660A4FEF6B65353|rigid:T8CT6M5+i3hMHQA8uHdfSES6urk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5L7Y0	uniprotkb:Q96A37	intact:EBI-2853824	intact:EBI-2130320|ensembl:ENSP00000326095.4|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8	psi-mi:a0a3g5l7y0_yerpe(display_long)|uniprotkb:sfcA2(gene name)|psi-mi:sfcA2(display_short)|uniprotkb:YP_2657(locus name)|uniprotkb:y1449(locus name)	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856062|imex:IM-13779-6068	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051674|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|interpro:IPR012188(Malic enzyme, phosphate acetyl/butaryl transferase)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR036291|interpro:IPR037062|interpro:IPR042112|interpro:IPR042113|uniprotkb:A0A6B3T265(uniprot-removed-ac)|go:""GO:0004470""(malic enzyme activity)|go:""GO:0006108""(malate metabolic process)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051287""(NAD binding)|interpro:IPR045213|refseq:WP_002224829.1|interpro:IPR046346"	"ensembl:ENSG00000158717.11(gene)|ensembl:ENST00000312838.9(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0005737""(cytoplasm)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006914""(autophagy)|go:""GO:0045087""(innate immune response)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR051438|refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|panther:PTHR46016(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:stWUfKx3Suo1T8GcyMQBEsNHMII632	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	intact-crc:4DC462BEFD9EFD37|rigid:7jeseQzcjBE1gax0RWXjJBQ3LbA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CGS4	uniprotkb:Q96A37	intact:EBI-2846699|uniprotkb:Q74QG3	intact:EBI-2130320|ensembl:ENSP00000326095.4|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8	psi-mi:e4pd_yerpe(display_long)|uniprotkb:epd(gene name)|psi-mi:epd(display_short)|uniprotkb:YPO0922(locus name)|uniprotkb:y3309(locus name)|uniprotkb:YP_3518(locus name)	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856076|imex:IM-13779-6070	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006422(D-erythrose-4-phosphate dehydrogenase)|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|refseq:WP_002209964.1|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0008615""(pyridoxine biosynthetic process)|go:""GO:0042823""(pyridoxal phosphate biosynthetic process)|go:""GO:0048001""(erythrose-4-phosphate dehydrogenase activity)|go:""GO:0051287""(NAD binding)|interpro:IPR036291|refseq:YP_002345970.1|panther:PTHR43148(orthology-group)"	"ensembl:ENSG00000158717.11(gene)|ensembl:ENST00000312838.9(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0005737""(cytoplasm)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006914""(autophagy)|go:""GO:0045087""(innate immune response)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR051438|refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|panther:PTHR46016(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PzUDobm36XTKelGxo57qKYNpTgk632	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	intact-crc:08CA86771256ABF4|rigid:mJDhWH/qbIQewTklUDBEtUpwMyE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ND24	uniprotkb:A0A2S9PFM0	intact:EBI-2856054|uniprotkb:B4DTD1|uniprotkb:B2RUW0|ensembl:ENSP00000300650.4|ensembl:ENSP00000431643.1	intact:EBI-2846871|uniprotkb:Q74QH1|uniprotkb:A0A0H2W7H4|uniprotkb:Q7CGR9|uniprotkb:A0A384LFS9	psi-mi:rn214_human(display_long)|uniprotkb:RNF214(gene name)|psi-mi:RNF214(display_short)	psi-mi:a0a2s9pfm0_yerpe(display_long)|uniprotkb:YPO0938(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856051|imex:IM-13779-6067	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001265178.1|refseq:NP_001070707.1|refseq:NP_997226.2|ensembl:ENSG00000167257.11(gene)|ensembl:ENST00000300650.9(transcript)|ensembl:ENST00000531452.5(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q8ND24|panther:PTHR15727(orthology-group)"	"interpro:IPR017755(N-carbamoylputrescine amidase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:WP_002209979.1|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0050126""(N-carbamoylputrescine amidase activity)|interpro:IPR036526|refseq:YP_002345985.1|interpro:IPR050345"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hn6cadtHWcJXcGn2WsaBNdQkTow9606	rogid:VEt5ZICBEzJqD2dQaZCgWKgplSI632	intact-crc:8EB3E3C1DBD45520|rigid:2fZmjtpj8P8i6yMWDeQHhTQLXjY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96A37	uniprotkb:A0A0H2W1D0	intact:EBI-2130320|ensembl:ENSP00000326095.4|uniprotkb:B3KQ03|uniprotkb:Q96DM0|uniprotkb:D3DX75|uniprotkb:H3BTU8	intact:EBI-2850611|uniprotkb:Q74XN0|uniprotkb:Q0WBY0|uniprotkb:A0A3N4B5H8|uniprotkb:Q7CKA0|uniprotkb:A0A384KPX7	psi-mi:rn166_human(display_long)|uniprotkb:RNF166(gene name)|psi-mi:RNF166(display_short)|uniprotkb:RING finger protein 166(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF166(gene name synonym)	psi-mi:a0a0h2w1d0_yerpe(display_long)|uniprotkb:YPO3312(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856069|imex:IM-13779-6069	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000158717.11(gene)|ensembl:ENST00000312838.9(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0005737""(cytoplasm)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006914""(autophagy)|go:""GO:0045087""(innate immune response)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR034734|interpro:IPR051438|refseq:NP_001165286.1|refseq:NP_001165287.1|refseq:NP_849163.1|refseq:XP_016878402.1|panther:PTHR46016(orthology-group)"	"interpro:IPR018485|interpro:IPR018484|interpro:IPR000577(Carbohydrate kinase, FGGY)|refseq:WP_002209440.1|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016301""(kinase activity)|interpro:IPR043129|interpro:IPR042016|refseq:YP_002348208.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QV195sbjVofHePvnO8nsleiWSkg9606	rogid:TkbiVPrlraU0BBleepm9BhezvWk632	intact-crc:5B5C4D7FDDA83089|rigid:nho8I/MutNXyhhh65y7t/BJPYoQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94763	uniprotkb:Q8ZJP8	intact:EBI-357067|uniprotkb:A8K805|uniprotkb:Q9UNU3|intact:EBI-2683009|uniprotkb:H7BY42|uniprotkb:Q8TC23|ensembl:ENSP00000376097.2	intact:EBI-2847365|uniprotkb:Q0WKP8	psi-mi:rmp_human(display_long)|uniprotkb:URI1(gene name)|psi-mi:URI1(display_short)|uniprotkb:C19orf2(gene name synonym)|uniprotkb:NNX3(gene name synonym)|uniprotkb:PPP1R19(gene name synonym)|uniprotkb:Protein NNX3(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 19(gene name synonym)|uniprotkb:RMP(gene name synonym)|uniprotkb:RNA polymerase II subunit 5-mediating protein(gene name synonym)|uniprotkb:URI(gene name synonym)	psi-mi:rnph_yerpe(display_long)|uniprotkb:rph(gene name)|psi-mi:rph(display_short)|uniprotkb:tRNA nucleotidyltransferase(gene name synonym)|uniprotkb:YPO0044(locus name)|uniprotkb:y0097(locus name)|uniprotkb:YP_0045(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856102|imex:IM-13779-6075	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003787.2|refseq:NP_001239570.1|ensembl:ENSG00000105176.18(gene)|ensembl:ENST00000392271.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0009615""(response to virus)|go:""GO:0010923""(negative regulation of phosphatase activity)|go:""GO:0019212""(phosphatase inhibitor activity)|go:""GO:0030425""(dendrite)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0050821""(protein stabilization)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR052255|mint:O94763|panther:PTHR15111(orthology-group)"	"interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR002381(Ribonuclease phosphorolytic, bacterial-type)|interpro:IPR018336|interpro:IPR027408|refseq:WP_002208997.1|go:""GO:0000049""(tRNA binding)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0003723""(RNA binding)|go:""GO:0006364""(rRNA processing)|go:""GO:0008033""(tRNA processing)|go:""GO:0009022""(tRNA nucleotidyltransferase activity)|go:""GO:0016075""(rRNA catabolic process)|interpro:IPR036345|refseq:YP_002345140.1|interpro:IPR050080|panther:PTHR11953(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:izqLgjD5/WAkdmUp7K8hIQ+cGxE9606	rogid:w1ahukqHBCGll+OW4Q9GEEimgOY632	intact-crc:526ACEBA2844F9B4|rigid:4V4UZvFzDEb2JJAvhZvfcB8qeyQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D053	uniprotkb:Q06587	intact:EBI-2854358|uniprotkb:Q74VV1	intact:EBI-752313|ensembl:ENSP00000363787.4|ensembl:ENSP00000372699.4|ensembl:ENSP00000396271.2|ensembl:ENSP00000396439.2|ensembl:ENSP00000400572.2|ensembl:ENSP00000412190.2|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0	psi-mi:q8d053_yerpe(display_long)|uniprotkb:pqiB(gene name)|psi-mi:pqiB(display_short)|uniprotkb:pqiB1(gene name synonym)|uniprotkb:YP_1172(locus name)|uniprotkb:y2747(locus name)	psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:RING1A(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856109|imex:IM-13779-6074	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051800|interpro:IPR003399(Mammalian cell entry related)|go:""GO:0016020""(membrane)"	"ensembl:ENSG00000204227.5(gene)|ensembl:ENSG00000206287.5(gene)|ensembl:ENSG00000226788.3(gene)|ensembl:ENSG00000228520.3(gene)|ensembl:ENSG00000231115.3(gene)|ensembl:ENSG00000235107.3(gene)|ensembl:ENST00000374656.5(transcript)|ensembl:ENST00000383212.4(transcript)|ensembl:ENST00000415941.2(transcript)|ensembl:ENST00000427374.2(transcript)|ensembl:ENST00000430233.2(transcript)|ensembl:ENST00000436128.2(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001739""(sex chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0009952""(anterior/posterior pattern specification)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016607""(nuclear speck)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048593""(camera-type eye morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0097027""(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR043540|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-42043N|refseq:NP_002922.2|panther:PTHR46076(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:A52nN/Y0rkWA9ZIgkm8/dIpb+sI632	rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606	intact-crc:39325560A2164BCC|rigid:FKaGmHJIe1FhkTUp7Vzb2JueUg0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YHK6	uniprotkb:Q9H9V4	intact:EBI-2856093|uniprotkb:A0A0H2W5D6|uniprotkb:Q74SI7|uniprotkb:Q7CJF5|uniprotkb:A0A384KU48	intact:EBI-2129998|uniprotkb:Q52LK3|ensembl:ENSP00000256257.1	psi-mi:a0a5p8yhk6_yerpe(display_long)|uniprotkb:cysK(gene name)|psi-mi:cysK(display_short)|uniprotkb:cysZ(gene name synonym)|uniprotkb:YPO2992(locus name)	psi-mi:rn122_human(display_long)|uniprotkb:RNF122(gene name)|psi-mi:RNF122(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856090|imex:IM-13779-6072	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR005856(Cysteine synthase K/M)|interpro:IPR005859(Cysteine synthase A)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR050214|refseq:WP_002222180.1|go:""GO:0004124""(cysteine synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006535""(cysteine biosynthetic process from serine)|go:""GO:0080146""(L-cysteine desulfhydrase activity)|interpro:IPR036052|refseq:YP_002347916.1|panther:PTHR10314(orthology-group)"	"refseq:NP_079063.2|ensembl:ENSG00000133874.2(gene)|ensembl:ENST00000256257.2(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0010917""(negative regulation of mitochondrial membrane potential)|go:""GO:0016020""(membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR051834|panther:PTHR22763(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UrC5dh7j9HnS/MZkY6/7kxZcpME632	rogid:mNEF3wyRPfB1WyLpF+I27YBAqzQ9606	intact-crc:C4B625BA0CA7A135|rigid:i4uuc/E8NqMkW0jZU1/7lLUXlUk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZM3	uniprotkb:Q96NA2	intact:EBI-2842197|uniprotkb:Q74YC6	intact:EBI-2856119|uniprotkb:B2RBQ8|uniprotkb:Q9BSL3|uniprotkb:Q71RE6|uniprotkb:Q9BYS3|ensembl:ENSP00000301336.6|ensembl:ENSP00000481849.1	psi-mi:q8czm3_yerpe(display_long)|uniprotkb:hemN(gene name)|psi-mi:hemN(display_short)|uniprotkb:hemN1(gene name synonym)|uniprotkb:YP_0022(locus name)|uniprotkb:y3807(locus name)	psi-mi:rilp_human(display_long)|uniprotkb:RILP(gene name)|psi-mi:RILP(display_short)|uniprotkb:PP10141(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856116|imex:IM-13779-6073	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004558(Oxygen-independent coproporphyrinogen III oxidase HemN)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR010723(HemN, C-terminal)|interpro:IPR007197(Radical SAM)|interpro:IPR013785(Aldolase-type TIM barrel)|go:""GO:0004109""(coproporphyrinogen oxidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0051989""(coproporphyrinogen dehydrogenase activity)|interpro:IPR034505"	"refseq:NP_113618.2|ensembl:ENSG00000167705.12(gene)|ensembl:ENSG00000274145.2(gene)|ensembl:ENST00000301336.7(transcript)|ensembl:ENST00000622136.2(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0015031""(protein transport)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032509""(endosome transport via multivesicular body sorting pathway)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051959""(dynein light intermediate chain binding)|go:""GO:0060271""(cilium assembly)|go:""GO:0070676""(intralumenal vesicle formation)|interpro:IPR021563|interpro:IPR034743|interpro:IPR034744|interpro:IPR051241|rcsb pdb:1YHN|reactome:R-HSA-2132295|dip:DIP-29458N|panther:PTHR21502(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	crc64:1057A1DAC2FFED94	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:J5m2HbtFIANx5IaV2zvcYnB7hYI632	rogid:dBBOnpVleCSq8//uqicphTGykw09606	intact-crc:A71D730B1C8F4F82|rigid:FAtIMx9LGNzMOmxX3J1TeBqkWtg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NC42	uniprotkb:P17778	intact:EBI-2801688|uniprotkb:Q8WUU3|uniprotkb:Q8NBY5|uniprotkb:Q8N5I8|uniprotkb:Q53S14|ensembl:ENSP00000295317.3	intact:EBI-2842665|uniprotkb:O68701	psi-mi:rn149_human(display_long)|uniprotkb:DNAPTP2(gene name synonym)|uniprotkb:DNA polymerase-transactivated protein 2(gene name synonym)|uniprotkb:RING finger protein 149(gene name synonym)|uniprotkb:RNF149(gene name)|psi-mi:RNF149(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF149(gene name synonym)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856083|imex:IM-13779-6071	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_775918.2|ensembl:ENSG00000163162.9(gene)|ensembl:ENST00000295317.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042712|interpro:IPR046450|mint:Q8NC42|panther:PTHR22765(orthology-group)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lKDjXVh73wnuRkXJHOtsWY6AwZI9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:01FDFA3245F663AC|rigid:6SSYED3QVerRaMfhMmVjPStS9I0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:P61586	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856145|imex:IM-13779-6080	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:E56791C815844F14|rigid:KyPzMEdlmem7Y2flwFr2tci75Rk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61586	uniprotkb:Q8ZCT9	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	intact:EBI-2844687|uniprotkb:Q0WD28	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	psi-mi:der_yerpe(display_long)|uniprotkb:der(gene name)|psi-mi:der(display_short)|uniprotkb:engA(gene name synonym)|uniprotkb:GTP-binding protein EngA(gene name synonym)|uniprotkb:YPO2875(locus name)|uniprotkb:y1357(locus name)|uniprotkb:YP_2741(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856152|imex:IM-13779-6079	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"interpro:IPR032859|interpro:IPR016484(GTP-binding, EngA)|interpro:IPR006073(GTP1/OBG)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR031166|go:""GO:0005525""(GTP binding)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0043022""(ribosome binding)|refseq:WP_002209813.1|refseq:YP_002347810.1|panther:PTHR43834(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	rogid:a3YV0SOJTAdEtPWBkgeX/kJ6UR8632	intact-crc:C9171F3AC8DF804E|rigid:Mjt1C3AIznM+ypH3wWf6lYXndfs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61586	uniprotkb:Q8ZAG5	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	intact:EBI-2856162|uniprotkb:Q74R71|uniprotkb:Q8D1J8|uniprotkb:Q0WAH3	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	psi-mi:cora_yerpe(display_long)|uniprotkb:corA(gene name)|psi-mi:corA(display_short)|uniprotkb:YPO3837(locus name)|uniprotkb:y0393(locus name)|uniprotkb:YP_3211(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856159|imex:IM-13779-6078	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"interpro:IPR004488(Magnesium and cobalt transport protein CorA)|interpro:IPR050829|refseq:WP_002211480.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015087""(cobalt ion transmembrane transporter activity)|go:""GO:0015095""(magnesium ion transmembrane transporter activity)|go:""GO:0015099""(nickel cation transmembrane transporter activity)|interpro:IPR002523(Mg2+ transporter protein, CorA-like)|refseq:YP_002348715.1|interpro:IPR045861|interpro:IPR045863|panther:PTHR47685(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	rogid:O9MJi8tdDrXdOixFtWEIlN2Psbw632	intact-crc:242EFD3ACB4EAC2F|rigid:hd3bK9lmfd/5NnwnPgVOxAX46PQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PDV6	uniprotkb:P61586	intact:EBI-2840553|uniprotkb:Q74T00|uniprotkb:A0A0H2W6Y4|uniprotkb:Q7CJA6	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000503282.1|ensembl:ENSP00000504180.1	psi-mi:a0a380pdv6_yerpe(display_long)|uniprotkb:asd(gene name)|psi-mi:asd(display_short)|uniprotkb:usg-1(gene name synonym)|uniprotkb:YPO2765(locus name)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856138|imex:IM-13779-6077	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000534(Semialdehyde dehydrogenase, NAD-binding)|interpro:IPR012280(Semialdehyde dehydrogenase, dimerisation region)|go:""GO:0004073""(aspartate-semialdehyde dehydrogenase activity)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051287""(NAD binding)|refseq:WP_002209726.1|refseq:YP_002347712.1|interpro:IPR036291|panther:PTHR46278(orthology-group)"	"panther:PTHR24072(orthology-group)|efo:""Orphanet:589608""|ensembl:ENSG00000067560.14(gene)|ensembl:ENST00000418115.6(transcript)|ensembl:ENST00000445425.6(transcript)|ensembl:ENST00000678200.1(transcript)|ensembl:ENST00000679208.1(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001764""(neuron migration)|go:""GO:0001822""(kidney development)|go:""GO:0001998""(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:""GO:0002363""(alpha-beta T cell lineage commitment)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0003189""(aortic valve formation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0017022""(myosin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035385""(Roundabout signaling pathway)|go:""GO:0036089""(cleavage furrow formation)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042476""(odontogenesis)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043197""(dendritic spine)|go:""GO:0043296""(apical junction complex)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043366""(beta selection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060193""(positive regulation of lipase activity)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0090324""(negative regulation of oxidative phosphorylation)|go:""GO:0097049""(motor neuron apoptotic process)|rcsb pdb:2RGN|go:""GO:0097498""(endothelial tube lumen extension)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902766""(skeletal muscle satellite cell migration)|go:""GO:1903427""(negative regulation of reactive oxygen species biosynthetic process)|go:""GO:1903673""(mitotic cleavage furrow formation)|go:""GO:1904695""(positive regulation of vascular associated smooth muscle contraction)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1905274""(regulation of modification of postsynaptic actin cytoskeleton)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:3KZ1|rcsb pdb:3LW8|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|rcsb pdb:7G80|rcsb pdb:7G81|rcsb pdb:7G82|rcsb pdb:7G83|rcsb pdb:7G84|rcsb pdb:7G85|rcsb pdb:7G86|rcsb pdb:7G87|rcsb pdb:7G88|rcsb pdb:7G89|rcsb pdb:7G8A|rcsb pdb:7G8B|rcsb pdb:7G8C|rcsb pdb:7G8D|rcsb pdb:7G8E|rcsb pdb:7G8F|rcsb pdb:7G8G|rcsb pdb:7G8H|rcsb pdb:7G8I|rcsb pdb:7G8J|rcsb pdb:7G8K|rcsb pdb:7G8L|rcsb pdb:7G8M|rcsb pdb:7G8N|rcsb pdb:7G8O|rcsb pdb:7G8P|rcsb pdb:7G8Q|rcsb pdb:7G8R|rcsb pdb:7G8S|rcsb pdb:7G8T|rcsb pdb:7G8U|rcsb pdb:7G8V|rcsb pdb:7G8W|rcsb pdb:7G8X|rcsb pdb:7G8Y|rcsb pdb:7G8Z|rcsb pdb:7G90|rcsb pdb:7G91|rcsb pdb:7G92|rcsb pdb:7G93|rcsb pdb:7G94|rcsb pdb:7G95|rcsb pdb:7G96|rcsb pdb:7G97|rcsb pdb:7G98|rcsb pdb:7G99|rcsb pdb:7G9A|rcsb pdb:7G9B|rcsb pdb:7G9C|rcsb pdb:7G9D|rcsb pdb:7G9E|rcsb pdb:7G9F|rcsb pdb:7G9G|rcsb pdb:7G9H|rcsb pdb:7G9I|rcsb pdb:7G9J|rcsb pdb:7QSC|rcsb pdb:7QTM|rcsb pdb:7WZA|rcsb pdb:7WZC|rcsb pdb:8BNT|rcsb pdb:8FC7|rcsb pdb:8FC9|rcsb pdb:8FCB|rcsb pdb:8FPW|rcsb pdb:8FPX|rcsb pdb:8GI3|rcsb pdb:8GI6|rcsb pdb:8JVJ|rcsb pdb:8T1C|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|refseq:NP_001300870.1|refseq:NP_001655.1|dip:DIP-29642N|ensembl:ENSP00000400175.1|ensembl:ENSP00000408402.3|ensembl:ENSP00000504180.1|ensembl:ENSP00000503282.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:uJbdLN4o1CmliMmX0uoqzanhqOw632	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	intact-crc:B14FC9E12F9285EA|rigid:dFX6xY9f21RcLOC2ISTwa1YA78Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04843	uniprotkb:Q8ZBZ9	intact:EBI-355963|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0|ensembl:ENSP00000296255.3	intact:EBI-2851065|uniprotkb:Q0WC55	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:dpo4_yerpe(display_long)|uniprotkb:dinP(gene name synonym)|uniprotkb:YPO3231(locus name)|uniprotkb:y0959(locus name)|uniprotkb:YP_0702(locus name)|uniprotkb:dinB(gene name)|psi-mi:dinB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856131|imex:IM-13779-6076	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:402020""|ensembl:ENSG00000163902.12(gene)|ensembl:ENST00000296255.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0042470""(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|rcsb pdb:8B6L|rcsb pdb:8PN9|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_002941.1|dip:DIP-38152N|panther:PTHR21049(orthology-group)"	"interpro:IPR043502|interpro:IPR017961|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR022880|refseq:WP_002208708.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0009432""(SOS response)|go:""GO:0042276""(error-prone translesion synthesis)|interpro:IPR043128|interpro:IPR036775|interpro:IPR053848|refseq:YP_002348133.1|interpro:IPR050116|panther:PTHR11076(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	rogid:dJC1TxxW9BoCSiFaklVosXbx3KY632	intact-crc:E58253D24CF9CDE8|rigid:9MFJ8xNGIxRUNLgRU7elcOXqUzo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H2S0	uniprotkb:Q6ZUM4	intact:EBI-2845117|uniprotkb:Q74SK9|uniprotkb:Q0WCU8|uniprotkb:Q7CJE4|uniprotkb:A0A384LH60	intact:EBI-2856199|uniprotkb:A8K3N5|uniprotkb:A4FU35|uniprotkb:Q494U0|uniprotkb:Q8WY58|uniprotkb:Q6NWZ8|uniprotkb:C9JTF3|ensembl:ENSP00000477741.1|ensembl:ENSP00000509127.1|intact:EBI-28984204	psi-mi:a0a2u2h2s0_yerpe(display_long)|uniprotkb:dmsB(gene name)|psi-mi:dmsB(display_short)|uniprotkb:YPO2966(locus name)	psi-mi:rhg27_human(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short)|uniprotkb:CAMGAP1(gene name synonym)|uniprotkb:SH3D20(gene name synonym)|uniprotkb:CIN85-associated multi-domain-containing Rho GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 27(gene name synonym)|uniprotkb:PP905(orf name)|uniprotkb:SH3 domain-containing protein 20(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856208|imex:IM-13779-6082	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR014297(Dimethylsulphoxide reductase, chain B)|interpro:IPR017900|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002211603.1|refseq:YP_002347890.1|interpro:IPR050954|panther:PTHR43177(orthology-group)"	"refseq:XP_006721808.1|refseq:NP_777579.2|refseq:NP_954976.1|refseq:NP_001269219.1|ensembl:ENSG00000159314.13(gene)|ensembl:ENSG00000276907.4(gene)|ensembl:ENST00000610792.3(transcript)|ensembl:ENST00000685559.1(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0051291""(protein heterooligomerization)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR036028|interpro:IPR050729|rcsb pdb:3PP2|reactome:R-HSA-9013148|reactome:R-HSA-9013149|panther:PTHR23176(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9jyIOCO41ainU3jSCjdpHqWlt50632	rogid:E5nmKdVVnfW2ee8Uc9nb6Nb3rkA9606	intact-crc:3D68D4248A4DA967|rigid:Za9jtwxNNq70rcQzQZiy0kKeJyQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHK5	uniprotkb:Q7Z6I6	intact:EBI-2840092|uniprotkb:Q0WIF2	intact:EBI-2814810|uniprotkb:Q5SY52|uniprotkb:Q6ZML6|uniprotkb:Q5SY53|uniprotkb:Q7Z3J8|uniprotkb:Q86XI7|uniprotkb:Q5SY54|ensembl:ENSP00000356992.3	psi-mi:syk_yerpe(display_long)|uniprotkb:lysS(gene name)|psi-mi:lysS(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO0888(locus name)|uniprotkb:YP_3584(locus name)|uniprotkb:y3272(locus name)	psi-mi:rhg30_human(display_long)|uniprotkb:ARHGAP30(gene name)|psi-mi:ARHGAP30(display_short)|uniprotkb:Rho-type GTPase-activating protein 30(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856173|imex:IM-13779-6081	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR044136|go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|refseq:WP_002209930.1|interpro:IPR034762|refseq:YP_002345936.1|interpro:IPR045864|panther:PTHR42918(orthology-group)"	"refseq:XP_011507693.1|refseq:NP_001020769.1|refseq:NP_859071.2|refseq:NP_001274529.1|refseq:NP_001274531.1|refseq:XP_005245130.1|ensembl:ENSG00000186517.14(gene)|ensembl:ENST00000368013.8(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005829""(cytosol)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR051576|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420|panther:PTHR15729(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7RLsEIl+oAzL6AY+mxY4y8mj2AM632	rogid:L0Pbx3s9V/lw/NAiHZHnvXwI8Hw9606	intact-crc:47EA3E725AC7065C|rigid:hDjZK9lD/meIQpI3j8feWTkrhSE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIL4	uniprotkb:Q52LW3	intact:EBI-2852663|uniprotkb:Q0WJI3	intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526.6	psi-mi:carb_yerpe(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:YPO0482(locus name)|uniprotkb:YP_3697(locus name)|uniprotkb:y3692(locus name)	psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856192|imex:IM-13779-6083	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|refseq:WP_002210502.1|go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR033937|interpro:IPR036897|interpro:IPR036914|refseq:YP_002345555.1|panther:PTHR11405(orthology-group)"	"efo:""Orphanet:199306""|ensembl:ENSG00000137962.13(gene)|ensembl:ENST00000260526.11(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0051058""(negative regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR046349|interpro:IPR051025|interpro:IPR054713|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_001315593.1|refseq:NP_004806.3|refseq:XP_011540741.1|panther:PTHR15228(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l/RzabCD1P/dEo/AmaYoXpYV1FY632	rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606	intact-crc:B87C6759220FB1EB|rigid:CeWjNbsjZ2xQEo4drtBPSW4Pmv8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q52LW3	uniprotkb:A0A5P8YDJ2	intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526.6	intact:EBI-2856183|uniprotkb:A0A0H2W964|uniprotkb:Q74QL2|uniprotkb:A0A2U2H0T9|uniprotkb:Q7CGP1|uniprotkb:A0A384KAF1	psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym)	psi-mi:a0a5p8ydj2_yerpe(display_long)|uniprotkb:YPO0986(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856180|imex:IM-13779-6084	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:199306""|ensembl:ENSG00000137962.13(gene)|ensembl:ENST00000260526.11(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0051058""(negative regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR046349|interpro:IPR051025|interpro:IPR054713|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_001315593.1|refseq:NP_004806.3|refseq:XP_011540741.1|panther:PTHR15228(orthology-group)"	interpro:IPR006311(Twin-arginine translocation pathway signal)|refseq:WP_002211654.1|interpro:IPR050955|interpro:IPR029058|interpro:IPR041172|refseq:YP_002346033.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606	rogid:D0e6VAzeYAQwUN3mCgDECU+Rcg0632	intact-crc:3691E11013AA0DDB|rigid:0nqBppn7b/QzkEykaOjyYVC4cgw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49796	uniprotkb:A0A3N4B4H4	intact:EBI-2107809|uniprotkb:A6NHA0|uniprotkb:Q8NFN6|uniprotkb:Q8WXA0|uniprotkb:Q5VXC1|uniprotkb:Q5VZ05|uniprotkb:Q6ZRM5|uniprotkb:Q8IUQ1|uniprotkb:Q8NC47|uniprotkb:Q8NFN4|uniprotkb:Q8NFN5|uniprotkb:Q8TD59|uniprotkb:Q8TD68|uniprotkb:B3KUB2|uniprotkb:A8K0V1|uniprotkb:Q5VXB8|uniprotkb:Q5VZ06|uniprotkb:Q8WV02|ensembl:ENSP00000259406.7|ensembl:ENSP00000363255.2	intact:EBI-2856246|uniprotkb:A0A0H2W865|uniprotkb:Q74QF7|uniprotkb:Q7CGX7|uniprotkb:A0A384L6E2	psi-mi:rgs3_human(display_long)|uniprotkb:RGS3(gene name)|psi-mi:RGS3(display_short)	psi-mi:a0a3n4b4h4_yerpe(display_long)|uniprotkb:YPO0829(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856243|imex:IM-13779-6087	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269851.1|refseq:NP_001269852.1|refseq:XP_006717282.1|refseq:NP_060260.3|refseq:NP_570613.2|refseq:NP_652759.3|refseq:NP_001263189.1|refseq:NP_001263191.1|refseq:NP_602299.1|refseq:NP_652760.2|panther:PTHR46848(orthology-group)|refseq:NP_001263190.1|refseq:XP_006717289.1|refseq:XP_006717293.1|refseq:XP_011517198.1|refseq:XP_011517199.1|refseq:XP_011517200.1|refseq:XP_011517202.1|refseq:XP_011517203.1|refseq:XP_016870494.1|refseq:XP_016870495.1|ensembl:ENSG00000138835.24(gene)|ensembl:ENST00000350696.9(transcript)|ensembl:ENST00000374140.6(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0009968""(negative regulation of signal transduction)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR034951|interpro:IPR035892|interpro:IPR036034|interpro:IPR036305|interpro:IPR044926|mint:P49796|rcsb pdb:2F5Y|rcsb pdb:2OJ4|rcsb pdb:3FBK|reactome:R-HSA-416476|reactome:R-HSA-418594"	"refseq:WP_002209873.1|interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR000917(Sulphatase)|interpro:IPR050738|go:""GO:0004065""(arylsulfatase activity)|refseq:YP_002345881.1|panther:PTHR42693(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xe1DKEKnIxEZ6X2F97smZSW2FrA9606	rogid:FVCatv0xoCiBjs5b3zxfMTBJ3+g632	intact-crc:60125FA5F5511F3D|rigid:zg1sqkrN2QQXwZlwXCwTqSo57lQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P68587	uniprotkb:P49796	intact:EBI-2844901|uniprotkb:P40295	intact:EBI-2107809|uniprotkb:A6NHA0|uniprotkb:Q8NFN6|uniprotkb:Q8WXA0|uniprotkb:Q5VXC1|uniprotkb:Q5VZ05|uniprotkb:Q6ZRM5|uniprotkb:Q8IUQ1|uniprotkb:Q8NC47|uniprotkb:Q8NFN4|uniprotkb:Q8NFN5|uniprotkb:Q8TD59|uniprotkb:Q8TD68|uniprotkb:B3KUB2|uniprotkb:A8K0V1|uniprotkb:Q5VXB8|uniprotkb:Q5VZ06|uniprotkb:Q8WV02|ensembl:ENSP00000259406.7|ensembl:ENSP00000363255.2	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	psi-mi:rgs3_human(display_long)|uniprotkb:RGS3(gene name)|psi-mi:RGS3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856229|imex:IM-13779-6089	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"refseq:NP_001269851.1|refseq:NP_001269852.1|refseq:XP_006717282.1|refseq:NP_060260.3|refseq:NP_570613.2|refseq:NP_652759.3|refseq:NP_001263189.1|refseq:NP_001263191.1|refseq:NP_602299.1|refseq:NP_652760.2|panther:PTHR46848(orthology-group)|refseq:NP_001263190.1|refseq:XP_006717289.1|refseq:XP_006717293.1|refseq:XP_011517198.1|refseq:XP_011517199.1|refseq:XP_011517200.1|refseq:XP_011517202.1|refseq:XP_011517203.1|refseq:XP_016870494.1|refseq:XP_016870495.1|ensembl:ENSG00000138835.24(gene)|ensembl:ENST00000350696.9(transcript)|ensembl:ENST00000374140.6(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0009968""(negative regulation of signal transduction)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR034951|interpro:IPR035892|interpro:IPR036034|interpro:IPR036305|interpro:IPR044926|mint:P49796|rcsb pdb:2F5Y|rcsb pdb:2OJ4|rcsb pdb:3FBK|reactome:R-HSA-416476|reactome:R-HSA-418594"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	rogid:Xe1DKEKnIxEZ6X2F97smZSW2FrA9606	intact-crc:B3F08238E1505916|rigid:p59TxJSHbmY7BhlMNhD2Oiic9yA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZC18	uniprotkb:P98171	intact:EBI-2851256|uniprotkb:Q0WC74	intact:EBI-2796462|ensembl:ENSP00000203786.8|uniprotkb:Q14144|uniprotkb:Q86UY3	psi-mi:rdgc_yerpe(display_long)|uniprotkb:rdgC(gene name)|psi-mi:rdgC(display_short)|uniprotkb:YPO3212(locus name)|uniprotkb:y0974(locus name)|uniprotkb:YP_0723(locus name)	psi-mi:rhg04_human(display_long)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856215|imex:IM-13779-6085	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007476(Putative exonuclease, RdgC)|refseq:WP_002208691.1|go:""GO:0000018""(regulation of DNA recombination)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006310""(DNA recombination)|go:""GO:0043590""(bacterial nucleoid)|refseq:YP_002348114.1|panther:PTHR38103(orthology-group)"	"ensembl:ENSG00000089820.17(gene)|ensembl:ENST00000350060.10(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030426""(growth cone)|go:""GO:0030517""(negative regulation of axon extension)|go:""GO:0042802""(identical protein binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035678|interpro:IPR036028|interpro:IPR051627|mint:P98171|rcsb pdb:2EPD|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_001158213.1|refseq:NP_001657.3|dip:DIP-41592N|panther:PTHR14166(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fjThsIbDKuwXOUDaMBLbS+Ab+F0632	rogid:WVlgmfAiXK06tLaxc8utjbtRa2Y9606	intact-crc:F4D0B10E5E34E432|rigid:zLUzZU5+qpMjDHnL3h7jW1JpgHc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YGL4	uniprotkb:Q07960	intact:EBI-2842269	intact:EBI-602762|uniprotkb:D3DQQ6|ensembl:ENSP00000310491.4	psi-mi:a0a5p8ygl4_yerpe(display_long)|uniprotkb:y2085(locus name)|uniprotkb:rnfC(gene name)|psi-mi:rnfC(display_short)|uniprotkb:Rnf electron transport complex subunit C(gene name synonym)	psi-mi:rhg01_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-related small GTPase protein activator(gene name synonym)|uniprotkb:p50-RhoGAP(gene name synonym)|uniprotkb:CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP1(gene name)|psi-mi:ARHGAP1(display_short)|uniprotkb:CDC42GAP(gene name synonym)|uniprotkb:RHOGAP1(gene name synonym)|uniprotkb:GTPase-activating protein rhoGAP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856222|imex:IM-13779-6086	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010208(Electron transport complex, RnfC)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR017896|interpro:IPR017900|interpro:IPR019554|interpro:IPR026902|interpro:IPR037225|refseq:WP_002223606.1|uniprotkb:Q8D0I9(uniprot-removed-ac)|go:""GO:0005886""(plasma membrane)|go:""GO:0009055""(electron transfer activity)|go:""GO:0022900""(electron transport chain)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)"	"refseq:NP_004299.1|ensembl:ENSG00000175220.12(gene)|ensembl:ENST00000311956.9(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0010008""(endosome membrane)|go:""GO:0016197""(endosomal transport)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0033572""(transferrin transport)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0070062""(extracellular exosome)|reactome:R-HSA-9696270|go:""GO:2001136""(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|interpro:IPR049592|mint:Q07960|rcsb pdb:1AM4|rcsb pdb:1GRN|rcsb pdb:1OW3|rcsb pdb:1RGP|rcsb pdb:1TX4|rcsb pdb:2NGR|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:6R3V|rcsb pdb:7QSC|rcsb pdb:7QTM|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|refseq:XP_011518397.1|dip:DIP-6081N|panther:PTHR45808(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:NRqQl9HrLq9sWIRyxpxhQ0JPxQo632	rogid:ceA3oLsnddhLiSbylS89P64mYBo9606	intact-crc:5CEA12FE2B1A155B|rigid:1oLOWi2n85oHO2+mgYWb7VeRPM0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17778	uniprotkb:P49796	intact:EBI-2842665|uniprotkb:O68701	intact:EBI-2107809|uniprotkb:A6NHA0|uniprotkb:Q8NFN6|uniprotkb:Q8WXA0|uniprotkb:Q5VXC1|uniprotkb:Q5VZ05|uniprotkb:Q6ZRM5|uniprotkb:Q8IUQ1|uniprotkb:Q8NC47|uniprotkb:Q8NFN4|uniprotkb:Q8NFN5|uniprotkb:Q8TD59|uniprotkb:Q8TD68|uniprotkb:B3KUB2|uniprotkb:A8K0V1|uniprotkb:Q5VXB8|uniprotkb:Q5VZ06|uniprotkb:Q8WV02|ensembl:ENSP00000259406.7|ensembl:ENSP00000363255.2	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	psi-mi:rgs3_human(display_long)|uniprotkb:RGS3(gene name)|psi-mi:RGS3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856236|imex:IM-13779-6088	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"refseq:NP_001269851.1|refseq:NP_001269852.1|refseq:XP_006717282.1|refseq:NP_060260.3|refseq:NP_570613.2|refseq:NP_652759.3|refseq:NP_001263189.1|refseq:NP_001263191.1|refseq:NP_602299.1|refseq:NP_652760.2|panther:PTHR46848(orthology-group)|refseq:NP_001263190.1|refseq:XP_006717289.1|refseq:XP_006717293.1|refseq:XP_011517198.1|refseq:XP_011517199.1|refseq:XP_011517200.1|refseq:XP_011517202.1|refseq:XP_011517203.1|refseq:XP_016870494.1|refseq:XP_016870495.1|ensembl:ENSG00000138835.24(gene)|ensembl:ENST00000350696.9(transcript)|ensembl:ENST00000374140.6(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0009968""(negative regulation of signal transduction)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR034951|interpro:IPR035892|interpro:IPR036034|interpro:IPR036305|interpro:IPR044926|mint:P49796|rcsb pdb:2F5Y|rcsb pdb:2OJ4|rcsb pdb:3FBK|reactome:R-HSA-416476|reactome:R-HSA-418594"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	rogid:Xe1DKEKnIxEZ6X2F97smZSW2FrA9606	intact-crc:2557ABF5B5222F0E|rigid:zr57V4Kvvziu+Y4xpSc+yywElY4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49796	uniprotkb:A0A380PIV1	intact:EBI-2107809|uniprotkb:A6NHA0|uniprotkb:Q8NFN6|uniprotkb:Q8WXA0|uniprotkb:Q5VXC1|uniprotkb:Q5VZ05|uniprotkb:Q6ZRM5|uniprotkb:Q8IUQ1|uniprotkb:Q8NC47|uniprotkb:Q8NFN4|uniprotkb:Q8NFN5|uniprotkb:Q8TD59|uniprotkb:Q8TD68|uniprotkb:B3KUB2|uniprotkb:A8K0V1|uniprotkb:Q5VXB8|uniprotkb:Q5VZ06|uniprotkb:Q8WV02|ensembl:ENSP00000259406.7|ensembl:ENSP00000363255.2	intact:EBI-2856258|uniprotkb:Q0WK78|uniprotkb:Q74XY2|uniprotkb:Q7CFT0|uniprotkb:A0A384K961	psi-mi:rgs3_human(display_long)|uniprotkb:RGS3(gene name)|psi-mi:RGS3(display_short)	psi-mi:a0a380piv1_yerpe(display_long)|uniprotkb:prlA(gene name)|psi-mi:prlA(display_short)|uniprotkb:secY(gene name synonym)|uniprotkb:YPO0229(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856255|imex:IM-13779-6090	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269851.1|refseq:NP_001269852.1|refseq:XP_006717282.1|refseq:NP_060260.3|refseq:NP_570613.2|refseq:NP_652759.3|refseq:NP_001263189.1|refseq:NP_001263191.1|refseq:NP_602299.1|refseq:NP_652760.2|panther:PTHR46848(orthology-group)|refseq:NP_001263190.1|refseq:XP_006717289.1|refseq:XP_006717293.1|refseq:XP_011517198.1|refseq:XP_011517199.1|refseq:XP_011517200.1|refseq:XP_011517202.1|refseq:XP_011517203.1|refseq:XP_016870494.1|refseq:XP_016870495.1|ensembl:ENSG00000138835.24(gene)|ensembl:ENST00000350696.9(transcript)|ensembl:ENST00000374140.6(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0009968""(negative regulation of signal transduction)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR034951|interpro:IPR035892|interpro:IPR036034|interpro:IPR036305|interpro:IPR044926|mint:P49796|rcsb pdb:2F5Y|rcsb pdb:2OJ4|rcsb pdb:3FBK|reactome:R-HSA-416476|reactome:R-HSA-418594"	"refseq:WP_002213344.1|interpro:IPR030659|interpro:IPR002208(SecY protein)|interpro:IPR023201|go:""GO:0005048""(signal sequence binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006616""(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0031522""(cell envelope Sec protein transport complex)|go:""GO:0043952""(protein transport by the Sec complex)|refseq:YP_002345310.1|interpro:IPR026593|panther:PTHR10906(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xe1DKEKnIxEZ6X2F97smZSW2FrA9606	rogid:h0OsEa4fyd7foYDOa0RXtb8gdak632	intact-crc:AEF7EDFBB4D0339A|rigid:37fYm1oW+APHT6hjp3twxuxk90I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48382	uniprotkb:A0A2S9PIH8	intact:EBI-923266|uniprotkb:Q5VWC3|uniprotkb:D3DV19|ensembl:ENSP00000290524.4|ensembl:ENSP00000357864.2|ensembl:ENSP00000389130.2|uniprotkb:B7Z848|uniprotkb:E9PFU4	intact:EBI-2845089|uniprotkb:Q74RZ9|uniprotkb:Q0WIN7|uniprotkb:Q7CGZ1|uniprotkb:A0A384KV76	psi-mi:rfx5_human(display_long)|uniprotkb:RFX5(gene name)|psi-mi:RFX5(display_short)|uniprotkb:Regulatory factor X 5(gene name synonym)	psi-mi:a0a2s9pih8_yerpe(display_long)|uniprotkb:lysA(gene name)|psi-mi:lysA(display_short)|uniprotkb:YPO0796(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856286|imex:IM-13779-6093	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143390.18(gene)|ensembl:ENST00000290524.8(transcript)|ensembl:ENST00000368870.6(transcript)|ensembl:ENST00000452671.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045348""(positive regulation of MHC class II biosynthetic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR029298|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|mint:P48382|rcsb pdb:2KW3|rcsb pdb:3V30|refseq:NP_000440.1|refseq:NP_001020774.1|refseq:XP_005245462.1|refseq:XP_005245463.1|refseq:XP_011508149.1|refseq:XP_011508150.1|refseq:XP_011508151.1|refseq:XP_011508152.1|efo:""Orphanet:572""|panther:PTHR12619(orthology-group)"	"interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR002986(Diaminopimelate decarboxylase)|interpro:IPR022643|interpro:IPR022644|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|interpro:IPR022653|interpro:IPR022657|interpro:IPR029066|go:""GO:0008836""(diaminopimelate decarboxylase activity)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:WP_002209846.1|refseq:YP_002345851.1|panther:PTHR43727(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kElLakR+ct4K8Mw6q91im3K8Zh89606	rogid:PVmk2FT176nUnOdaH1n3olLPC7Q632	intact-crc:DAF373E3FDC8ACD2|rigid:nVIlKzxw9v8xhPBXNZsmSbT7nKc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49796	uniprotkb:Q7ARN6	intact:EBI-2107809|uniprotkb:A6NHA0|uniprotkb:Q8NFN6|uniprotkb:Q8WXA0|uniprotkb:Q5VXC1|uniprotkb:Q5VZ05|uniprotkb:Q6ZRM5|uniprotkb:Q8IUQ1|uniprotkb:Q8NC47|uniprotkb:Q8NFN4|uniprotkb:Q8NFN5|uniprotkb:Q8TD59|uniprotkb:Q8TD68|uniprotkb:B3KUB2|uniprotkb:A8K0V1|uniprotkb:Q5VXB8|uniprotkb:Q5VZ06|uniprotkb:Q8WV02|ensembl:ENSP00000259406.7|ensembl:ENSP00000363255.2	intact:EBI-2839731|uniprotkb:Q7ARK0|uniprotkb:Q7BTY2|uniprotkb:A0A384L599|uniprotkb:Q7BT05|uniprotkb:A0A1U8QV46	psi-mi:rgs3_human(display_long)|uniprotkb:RGS3(gene name)|psi-mi:RGS3(display_short)	psi-mi:q7arn6_yerpe(display_long)|uniprotkb:DNA replication protein DnaC(gene name synonym)|uniprotkb:ISU56_03960(orf name)|uniprotkb:ISU56_05175(orf name)|uniprotkb:ISU56_08425(orf name)|uniprotkb:ISU56_14845(orf name)|uniprotkb:ISU59_17960(orf name)|uniprotkb:YPCD1.02(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856267|imex:IM-13779-6091	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269851.1|refseq:NP_001269852.1|refseq:XP_006717282.1|refseq:NP_060260.3|refseq:NP_570613.2|refseq:NP_652759.3|refseq:NP_001263189.1|refseq:NP_001263191.1|refseq:NP_602299.1|refseq:NP_652760.2|panther:PTHR46848(orthology-group)|refseq:NP_001263190.1|refseq:XP_006717289.1|refseq:XP_006717293.1|refseq:XP_011517198.1|refseq:XP_011517199.1|refseq:XP_011517200.1|refseq:XP_011517202.1|refseq:XP_011517203.1|refseq:XP_016870494.1|refseq:XP_016870495.1|ensembl:ENSG00000138835.24(gene)|ensembl:ENST00000350696.9(transcript)|ensembl:ENST00000374140.6(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0009968""(negative regulation of signal transduction)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR034951|interpro:IPR035892|interpro:IPR036034|interpro:IPR036305|interpro:IPR044926|mint:P49796|rcsb pdb:2F5Y|rcsb pdb:2OJ4|rcsb pdb:3FBK|reactome:R-HSA-416476|reactome:R-HSA-418594"	"refseq:NP_857639.1|refseq:NP_857717.1|refseq:NP_857781.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002611(IstB-like ATP-binding protein)|refseq:NP_395139.1|refseq:NP_395337.2|refseq:YP_006960970.1|interpro:IPR027417|interpro:IPR028350|go:""GO:0005524""(ATP binding)|go:""GO:0006260""(DNA replication)|go:""GO:0006269""(DNA replication, synthesis of primer)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:1990077""(primosome complex)|interpro:IPR047661|panther:PTHR30050(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xe1DKEKnIxEZ6X2F97smZSW2FrA9606	rogid:xE2EJm7k/XeOG5DV/dXhxV6bzD4632	intact-crc:00D8849C4D6E8AFC|rigid:WVGCyBGMyb3Y4e5eJtHFzI6tzqc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q3MIN7	uniprotkb:Q8ZDJ2	intact:EBI-2856274|uniprotkb:Q0P6G0|uniprotkb:B5ME84|uniprotkb:B7ZL22|ensembl:ENSP00000369823.3|uniprotkb:A0A0A0MRX4	intact:EBI-2844031|uniprotkb:Q0WDV6	psi-mi:rgl3_human(display_long)|uniprotkb:RGL3(gene name)|psi-mi:RGL3(display_short)	psi-mi:a2mgh_yerpe(display_long)|uniprotkb:YPO2573(locus name)|uniprotkb:y1143(locus name)|uniprotkb:YP_1141(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856279|imex:IM-13779-6094	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001030300.3|refseq:NP_001155088.2|ensembl:ENSG00000205517.13(gene)|ensembl:ENST00000380456.8(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0031267""(small GTPase binding)|interpro:IPR000159(Ras-association)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR030750|interpro:IPR036964|mint:Q3MIN7|reactome:R-HSA-5673001|panther:PTHR23113(orthology-group)"	"interpro:IPR021868|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|go:""GO:0004866""(endopeptidase inhibitor activity)|interpro:IPR041203|interpro:IPR041246|interpro:IPR041462|refseq:YP_002347532.1|interpro:IPR051802|panther:PTHR40094(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4pY8HWZbObW0azAaVL2kRXwOcwo9606	rogid:9FN1refl1me6jgo6ehCPO8MzV8Y632	intact-crc:CF1CD1C639600DAB|rigid:AwsHbyWkNps3eHZQt4B+pz9DMBs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13156	uniprotkb:Q9X6B0	intact:EBI-2856301|uniprotkb:Q3SY03|ensembl:ENSP00000362131.3	intact:EBI-2844324|intact:EBI-2856296|uniprotkb:Q0WBX3	psi-mi:rfa4_human(display_long)|uniprotkb:RPA4(gene name)|psi-mi:RPA4(display_short)|uniprotkb:Replication factor A protein 4(gene name synonym)	psi-mi:katg_yerpe(display_long)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)|uniprotkb:katY(gene name synonym)|uniprotkb:Antigen 5(gene name synonym)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:YPO3319(locus name)|uniprotkb:y0870(locus name)|uniprotkb:YP_0367(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856293|imex:IM-13779-6092	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037479.1|ensembl:ENSG00000204086.4(gene)|ensembl:ENST00000373040.4(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005662""(DNA replication factor A complex)|go:""GO:0006260""(DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006281""(DNA repair)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042162""(telomeric DNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|reactome:R-HSA-68962|dip:DIP-24241N|panther:PTHR13989(orthology-group)"	"interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|go:""GO:0004096""(catalase activity)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|refseq:WP_002209433.1|refseq:YP_002348215.1|panther:PTHR30555(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ks8XM/kYfzDLs2UimDd6CGb3+Is9606	rogid:RBebELhpxkVGfQv9Ix9rW4jzmpE632	intact-crc:799F8DAECC31C97C|rigid:yHrlsVfvLeVUWfI9twwFGpdtXO0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YIB0	uniprotkb:Q9GZR2	intact:EBI-2849936|uniprotkb:Q74W18|uniprotkb:Q0WDQ9|uniprotkb:Q7CJU5|uniprotkb:A0A384K8S0	intact:EBI-2856313|uniprotkb:Q5T8S4|uniprotkb:B2RAT2|uniprotkb:Q9GZW3|uniprotkb:Q5T8S6|uniprotkb:Q5T8S5|ensembl:ENSP00000361010.3|ensembl:ENSP00000486065.1	psi-mi:a0a5p8yib0_yerpe(display_long)|uniprotkb:asnB(gene name)|psi-mi:asnB(display_short)|uniprotkb:YPO2623(locus name)	psi-mi:rexo4_human(display_long)|uniprotkb:REXO4(gene name)|psi-mi:REXO4(display_short)|uniprotkb:PMC2(gene name synonym)|uniprotkb:XPMC2H(gene name synonym)|uniprotkb:Exonuclease XPMC2(gene name synonym)|uniprotkb:Prevents mitotic catastrophe 2 protein homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856310|imex:IM-13779-6095	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR001962(Asparagine synthase)|interpro:IPR017932|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033738|interpro:IPR029055|refseq:WP_002210348.1|go:""GO:0004066""(""asparagine synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006529""(asparagine biosynthetic process)|refseq:YP_002347579.1|interpro:IPR050795|panther:PTHR11772(orthology-group)"	"refseq:NP_001266278.1|refseq:NP_001266279.1|refseq:NP_001266280.1|refseq:NP_065118.2|ensembl:ENSG00000148300.12(gene)|ensembl:ENSG00000280706.3(gene)|ensembl:ENST00000371942.8(transcript)|ensembl:ENST00000630460.3(transcript)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006281""(DNA repair)|go:""GO:0006308""(DNA catabolic process)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006364""(rRNA processing)|go:""GO:0006396""(RNA processing)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0016607""(nuclear speck)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036397|interpro:IPR037431|interpro:IPR047021|mint:Q9GZR2|panther:PTHR12801(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/3AdfRR3qomx0JU+SwWtTPa2aeU632	rogid:N0OxZ2by59SnW1Xup2iaA29RPCU9606	intact-crc:2187F4C5F261D73E|rigid:HTo6K7tE025Vdwr6PFUtanqnW/E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H195	uniprotkb:O15258	intact:EBI-2856351|uniprotkb:Q0WK20|uniprotkb:A0A3N4B003|uniprotkb:Q7CKR0|uniprotkb:A0A384LAZ5	intact:EBI-716910|uniprotkb:O95322|ensembl:ENSP00000464222.1|ensembl:ENSP00000475168.1	psi-mi:a0a2u2h195_yerpe(display_long)|uniprotkb:YPO0286(locus name)	psi-mi:rer1_human(display_long)|uniprotkb:RER1(gene name)|psi-mi:RER1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856354|imex:IM-13779-6096	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002209066.1|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR026332|interpro:IPR034505|go:""GO:0003824""(catalytic activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051536""(iron-sulfur cluster binding)|refseq:YP_002345368.1"	"refseq:NP_008964.3|refseq:XP_006710369.1|refseq:XP_016855622.1|refseq:XP_016855623.1|refseq:XP_016855624.1|refseq:XP_011538844.1|refseq:XP_011538845.1|ensembl:ENSG00000157916.20(gene)|ensembl:ENST00000488353.2(transcript)|ensembl:ENST00000605895.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006621""(protein retention in ER lumen)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0009986""(cell surface)|go:""GO:0033130""(acetylcholine receptor binding)|go:""GO:0071340""(skeletal muscle acetylcholine-gated channel clustering)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|interpro:IPR004932(Retrieval of early ER protein Rer1)|mint:O15258|panther:PTHR10743(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Li7e0B3DlkLENa113dhTD5393Po632	rogid:rLTZIWGawmaVck0uemR5/E9bFRk9606	intact-crc:A1FD30EC09F588DA|rigid:0oAUiYg8AfhjVZVJtrSVWCkkd3U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZY2	uniprotkb:Q96R05	intact:EBI-2847648	intact:EBI-2856326|uniprotkb:B2R517|uniprotkb:Q5SWJ4|ensembl:ENSP00000294435.7	psi-mi:q8czy2_yerpe(display_long)|uniprotkb:recC(gene name)|psi-mi:recC(display_short)|uniprotkb:Exonuclease V subunit RecC(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecC(gene name synonym)|uniprotkb:y3166(locus name)	psi-mi:ret7_human(display_long)|uniprotkb:RBP7(gene name)|psi-mi:RBP7(display_short)|uniprotkb:Cellular retinoic acid-binding protein 4(gene name synonym)|uniprotkb:Cellular retinoic acid-binding protein IV(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856332|imex:IM-13779-6098	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002231332.1|interpro:IPR006697(Exodeoxyribonuclease V, RecC subunit)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0004519""(endonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR041500"	"refseq:NP_443192.1|ensembl:ENSG00000162444.12(gene)|ensembl:ENST00000294435.8(transcript)|go:""GO:0005504""(fatty acid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0015908""(fatty acid transport)|go:""GO:0016918""(retinal binding)|go:""GO:0019841""(retinol binding)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|rcsb pdb:1LPJ|rcsb pdb:6AT8|rcsb pdb:6E6K|panther:PTHR11955(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2Q4GsXvIqa5TrZjFD/kPigwGJNw632	rogid:75axWxV5mnxExd1avjdlOUK4o2E9606	intact-crc:0B2E26DC1A946CFE|rigid:saovyiHdw3SbABKldJxNKRcED1I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96A58	uniprotkb:A0A454XXH7	intact:EBI-2856342|uniprotkb:B2R9R0|uniprotkb:B4DI02|ensembl:ENSP00000256953.2|ensembl:ENSP00000438280.1|ensembl:ENSP00000441505.1	intact:EBI-2851240|uniprotkb:Q74Y15|uniprotkb:A0A0H2W158|uniprotkb:Q7CFV5|uniprotkb:A0A384K924	psi-mi:rerg_human(display_long)|uniprotkb:RERG(gene name)|psi-mi:RERG(display_short)	psi-mi:a0a454xxh7_yerpe(display_long)|uniprotkb:YPO0168(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856339|imex:IM-13779-6097	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001177655.1|refseq:NP_116307.1|ensembl:ENSG00000134533.6(gene)|ensembl:ENST00000256953.6(transcript)|ensembl:ENST00000536465.5(transcript)|ensembl:ENST00000538313.5(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009725""(response to hormone)|go:""GO:0019003""(GDP binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030331""(nuclear estrogen receptor binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR051065|rcsb pdb:2ATV|panther:PTHR24070(orthology-group)"	interpro:IPR027417|refseq:WP_002215686.1|interpro:IPR033186|refseq:YP_002345254.1|interpro:IPR051162|panther:PTHR30121(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZanMMlTztDFvruyi3UwghpbGcX89606	rogid:7T8Io5VjMpoAGWF393x9GYtAK2w632	intact-crc:5C9A17DEB72C94BA|rigid:Ftkt8DKqaV7AgQ/8frk9tjYFu0k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92785	uniprotkb:Q7ARD3	intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|uniprotkb:B4DT58|ensembl:ENSP00000436901.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856361|imex:IM-13779-6099	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1465""|ensembl:ENSG00000133884.11(gene)|ensembl:ENST00000528416.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0007399""(nervous system development)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0062072""(histone H3K9me2/3 reader activity)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0070577""(lysine-acetylated histone binding)|go:""GO:0071565""(nBAF complex)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:1905454""(negative regulation of myeloid progenitor cell differentiation)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-9824585|reactome:R-HSA-9845323|refseq:NP_006259.1|dip:DIP-27575N"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:82AB4D817AE128A2|rigid:UrcEAg9G7wIFlunl8d7Wbrm19k8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13123	uniprotkb:Q8ZHG3	intact:EBI-713456|uniprotkb:Q6IPD8|ensembl:ENSP00000396301.2	intact:EBI-2854674|uniprotkb:Q8CZV6|uniprotkb:Q0WIA5	psi-mi:red_human(display_long)|uniprotkb:Protein RER(gene name synonym)|uniprotkb:IK factor(gene name synonym)|uniprotkb:Cytokine IK(gene name synonym)|uniprotkb:IK(gene name)|psi-mi:IK(display_short)|uniprotkb:RED(gene name synonym)|uniprotkb:RER(gene name synonym)	psi-mi:y936_yerpe(display_long)|uniprotkb:YPO0936(locus name)|uniprotkb:y3322(locus name)|uniprotkb:YP_3506(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856389|imex:IM-13779-6101	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006074.2|ensembl:ENSG00000113141.19(gene)|ensembl:ENST00000417647.7(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000922""(spindle pole)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0016607""(nuclear speck)|go:""GO:0034501""(protein localization to kinetochore)|go:""GO:0042802""(identical protein binding)|go:""GO:0071005""(U2-type precatalytic spliceosome)|interpro:IPR012492(RED-like, C-terminal)|interpro:IPR012916(RED-like, N-terminal)|interpro:IPR039896|mint:Q13123|rcsb pdb:5O9Z|rcsb pdb:6Q8I|rcsb pdb:8QO9|rcsb pdb:8QZS|reactome:R-HSA-72163|panther:PTHR12765(orthology-group)"	"interpro:IPR003774(Protein of unknown function DUF179)|refseq:WP_002209977.1|go:""GO:0005829""(cytosol)|refseq:YP_002345983.1|panther:PTHR30327(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EBUQl+Gj0ozHP85Uh4xc9q2Vr6Y9606	rogid:mUyeIgl5pBHZwbB6q7lbZ88jLW0632	intact-crc:A1704B51194CF8E5|rigid:VYLKvmFKG75zn/LkSb/J8Y6+P+k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HAU5	uniprotkb:P58526	intact:EBI-372073|ensembl:ENSP00000348708.2|ensembl:ENSP00000350221.5|ensembl:ENSP00000380244.2|uniprotkb:A6NLJ5|uniprotkb:Q5W0J4|uniprotkb:Q14BM1|uniprotkb:Q8N8U1|uniprotkb:Q9H1J2|uniprotkb:Q9NWL1|uniprotkb:Q9P2D9|uniprotkb:Q9Y4M9|uniprotkb:D3DRS0|intact:EBI-28979373	intact:EBI-2851618|uniprotkb:Q0WE76	psi-mi:rent2_human(display_long)|uniprotkb:Up-frameshift suppressor 2 homolog(gene name synonym)|uniprotkb:UPF2(gene name)|psi-mi:UPF2(display_short)|uniprotkb:KIAA1408(gene name synonym)|uniprotkb:RENT2(gene name synonym)	psi-mi:mtox_yerpe(display_long)|uniprotkb:solA(gene name)|psi-mi:solA(display_short)|uniprotkb:YPO2448(locus name)|uniprotkb:y1742(locus name)|uniprotkb:YP_2268(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856368|imex:IM-13779-6100	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000151461.20(gene)|ensembl:ENST00000356352.6(transcript)|ensembl:ENST00000357604.10(transcript)|ensembl:ENST00000397053.6(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0001889""(liver development)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0035145""(exon-exon junction complex)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR007193(Up-frameshift suppressor 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039762|mint:Q9HAU5|rcsb pdb:1UW4|rcsb pdb:2WJV|rcsb pdb:4CEK|rcsb pdb:4CEM|rcsb pdb:7NWU|rcsb pdb:7QG6|reactome:R-HSA-9010553|reactome:R-HSA-975957|dip:DIP-31148N|refseq:NP_056357.1|refseq:NP_542166.1|panther:PTHR12839(orthology-group)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR023493|refseq:WP_002211850.1|go:""GO:0005829""(cytosol)|go:""GO:0008115""(sarcosine oxidase activity)|go:""GO:0050131""(N-methyl-L-amino-acid oxidase activity)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|refseq:YP_002347412.1|interpro:IPR045170|panther:PTHR10961(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:+hTMzl+IgYWyiDMSv5s4TeGt3D89606	rogid:CVPINp8wGJnyzKPXSUk8Tm4az0w632	intact-crc:DD5F0789CE1C58A2|rigid://VDm9OwGktBEyuchVt9ybVFyP0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P51606	uniprotkb:Q8D0N9	intact:EBI-752022|uniprotkb:Q96BI6|uniprotkb:B4DNZ3|ensembl:ENSP00000377303.3	intact:EBI-2845331|uniprotkb:Q74UJ0	psi-mi:renbp_human(display_long)|uniprotkb:N-acetyl-D-glucosamine 2-epimerase(gene name synonym)|uniprotkb:GlcNAc 2-epimerase(gene name synonym)|uniprotkb:Renin-binding protein(gene name synonym)|uniprotkb:RENBP(gene name)|psi-mi:RENBP(display_short)	psi-mi:q8d0n9_yerpe(display_long)|uniprotkb:pqiB2(gene name)|psi-mi:pqiB2(display_short)|uniprotkb:YP_1726(locus name)|uniprotkb:y1863(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856382|imex:IM-13779-6102	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002901.2|refseq:XP_016885187.1|ensembl:ENSG00000102032.13(gene)|ensembl:ENST00000393700.8(transcript)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006044""(N-acetylglucosamine metabolic process)|go:""GO:0006051""(N-acetylmannosamine metabolic process)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0019262""(N-acetylneuraminate catabolic process)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0050121""(N-acylglucosamine 2-epimerase activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010819(N-acylglucosamine 2-epimerase)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR034116|reactome:R-HSA-446210|panther:PTHR15108(orthology-group)"	"interpro:IPR003399(Mammalian cell entry related)|go:""GO:0016020""(membrane)|interpro:IPR051800"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RaAGBWNA09LPsbSWaALhjwl9N8Y9606	rogid:ubTQpOsKz5MxAzZCDHdFKkWSofo632	intact-crc:70D5CBD6A2CB1779|rigid:Y9L5MoBKU6tXg45eyi5wmQiZ32w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q92900	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142.1	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856375|imex:IM-13779-6103	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:NP_002902.2|ensembl:ENSG00000005007.14(gene)|ensembl:ENST00000599848.5(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0000932""(P-body)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006449""(regulation of translational termination)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032201""(telomere maintenance via semi-conservative replication)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0035145""(exon-exon junction complex)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0044530""(supraspliceosomal complex)|go:""GO:0044770""(cell cycle phase transition)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061014""(positive regulation of mRNA catabolic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1905746""(positive regulation of mRNA cis splicing, via spliceosome)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|interpro:IPR045055|interpro:IPR047187|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|rcsb pdb:8RXB|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001284478.1|dip:DIP-29875N|panther:PTHR10887(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606	intact-crc:9AF937CADE4B41F3|rigid:O4/l1adl/v+7UcjICd/XW5VFoQ0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49792	uniprotkb:A0A380PDY1	intact:EBI-973138|ensembl:ENSP00000283195.6|intact:EBI-28970106|uniprotkb:Q13074|uniprotkb:Q15280|uniprotkb:Q53TE2|uniprotkb:Q59FH7	intact:EBI-2848416|uniprotkb:Q74UI0|uniprotkb:A0A0H2W558|uniprotkb:Q7CIW0|uniprotkb:A0A384L8E0	psi-mi:rbp2_human(display_long)|uniprotkb:RANBP2(gene name)|psi-mi:RANBP2(display_short)|uniprotkb:NUP358(gene name synonym)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup358(gene name synonym)|uniprotkb:Nucleoporin Nup358(gene name synonym)|uniprotkb:358 kDa nucleoporin(gene name synonym)|uniprotkb:p270(gene name synonym)	psi-mi:a0a380pdy1_yerpe(display_long)|uniprotkb:ogl(gene name)|psi-mi:ogl(display_short)|uniprotkb:YPO1713(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856426|imex:IM-13779-6105	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000153201.17(gene)|ensembl:ENST00000283195.11(transcript)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005642""(annulate lamellae)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006111""(regulation of gluconeogenesis)|go:""GO:0006457""(protein folding)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0016020""(membrane)|go:""GO:0016925""(protein sumoylation)|go:""GO:0019789""(SUMO transferase activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042405""(nuclear inclusion body)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044614""(nuclear pore cytoplasmic filaments)|go:""GO:0044615""(nuclear pore nuclear basket)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051028""(mRNA transport)|go:""GO:0051168""(nuclear export)|go:""GO:0051642""(centrosome localization)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0106068""(SUMO ligase complex)|go:""GO:1990723""(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|interpro:IPR045255|mint:P49792|rcsb pdb:1RRP|rcsb pdb:1XKE|rcsb pdb:1Z5S|rcsb pdb:2LAS|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4GA0|rcsb pdb:4I9Y|rcsb pdb:4L6E|rcsb pdb:4LQW|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:7MNJ|rcsb pdb:7MNK|rcsb pdb:7MNL|rcsb pdb:7MNM|rcsb pdb:7MNN|rcsb pdb:7MNO|rcsb pdb:7MNP|rcsb pdb:7MNQ|rcsb pdb:7MNR|rcsb pdb:7MNS|rcsb pdb:7MNT|rcsb pdb:7MNU|rcsb pdb:7MNV|rcsb pdb:7MNW|rcsb pdb:7MNX|rcsb pdb:7MNY|rcsb pdb:7MNZ|rcsb pdb:7R5J|rcsb pdb:7R5K|rcsb pdb:9B62|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9648025|reactome:R-HSA-9705671|reactome:R-HSA-9725370|refseq:NP_006258.3|efo:""Orphanet:178342""|efo:""Orphanet:263524""|efo:""Orphanet:88619""|dip:DIP-37654N|panther:PTHR23138(orthology-group)"	"interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027946|refseq:WP_002210841.1|go:""GO:0045490""(pectin catabolic process)|go:""GO:0047487""(oligogalacturonide lyase activity)|refseq:YP_002346716.1|panther:PTHR36842(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:KB+rjfw8djVygvDpTncA0NO2MDY9606	rogid:e8mn+xTHxqbWMCnpEvzfGUD7MYI632	intact-crc:C4B058504698A4F5|rigid:Y0roiKmITE8ZzkN0rON56n5GQW8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W496	uniprotkb:Q92804	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	intact:EBI-2255091|ensembl:ENSP00000474096.1|ensembl:ENSP00000480040.1|uniprotkb:B2R837|uniprotkb:Q92751|intact:EBI-3867593|uniprotkb:Q86X94	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	psi-mi:rbp56_human(display_long)|uniprotkb:TAF15(gene name)|psi-mi:TAF15(display_short)|uniprotkb:RBP56(gene name synonym)|uniprotkb:TAF2N(gene name synonym)|uniprotkb:RNA-binding protein 56(gene name synonym)|uniprotkb:68 kDa TATA-binding protein-associated factor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856407|imex:IM-13779-6107	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"ensembl:ENSG00000270647.7(gene)|ensembl:ENSG00000276833.2(gene)|ensembl:ENST00000605844.6(transcript)|ensembl:ENST00000617382.2(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0008380""(RNA splicing)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048255""(mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q92804|rcsb pdb:2MMY|rcsb pdb:8ONS|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|refseq:NP_003478.1|refseq:NP_631961.1|dip:DIP-52760N|efo:""Orphanet:209916""|efo:""Orphanet:803""|panther:PTHR23238(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	rogid:9+wyDu+1dvocxFI4GKvLqkvChDc9606	intact-crc:55DD3959F30BCD0E|rigid:3ZjnNX3UCFPgTrCfy21Btx4EEu4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92804	uniprotkb:A0A0H2W636	intact:EBI-2255091|ensembl:ENSP00000474096.1|ensembl:ENSP00000480040.1|uniprotkb:B2R837|uniprotkb:Q92751|intact:EBI-3867593|uniprotkb:Q86X94	intact:EBI-2856417|uniprotkb:Q74RS7|uniprotkb:Q0WJ46|uniprotkb:A0A3N4B521|uniprotkb:Q7CGF4|uniprotkb:A0A384KSL1	psi-mi:rbp56_human(display_long)|uniprotkb:TAF15(gene name)|psi-mi:TAF15(display_short)|uniprotkb:RBP56(gene name synonym)|uniprotkb:TAF2N(gene name synonym)|uniprotkb:RNA-binding protein 56(gene name synonym)|uniprotkb:68 kDa TATA-binding protein-associated factor(gene name synonym)	psi-mi:a0a0h2w636_yerpe(display_long)|uniprotkb:YPO0623(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856414|imex:IM-13779-6106	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000270647.7(gene)|ensembl:ENSG00000276833.2(gene)|ensembl:ENST00000605844.6(transcript)|ensembl:ENST00000617382.2(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0008380""(RNA splicing)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048255""(mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q92804|rcsb pdb:2MMY|rcsb pdb:8ONS|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|refseq:NP_003478.1|refseq:NP_631961.1|dip:DIP-52760N|efo:""Orphanet:209916""|efo:""Orphanet:803""|panther:PTHR23238(orthology-group)"	"refseq:WP_002210373.1|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR050596|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:YP_002345692.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:9+wyDu+1dvocxFI4GKvLqkvChDc9606	rogid:yCgJ+OyMVo9sCEVG1Q3Ju+SJXmY632	intact-crc:961119694DE9B407|rigid:QLJTkLgtwUwKz5znnkM4WWvU0nM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZEJ5	uniprotkb:P25791	intact:EBI-2856396|uniprotkb:Q0WEZ2	intact:EBI-739696|uniprotkb:Q9HD58|ensembl:ENSP00000379175.3	psi-mi:y2172_yerpe(display_long)|uniprotkb:YPO2172(locus name)|uniprotkb:y2149(locus name)|uniprotkb:YP_1971(locus name)	psi-mi:rbtn2_human(display_long)|uniprotkb:LMO2(gene name)|psi-mi:LMO2(display_short)|uniprotkb:RBTN2(gene name synonym)|uniprotkb:RHOM2(gene name synonym)|uniprotkb:TTG2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym)|uniprotkb:RBTNL1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856400|imex:IM-13779-6104	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002210666.1|interpro:IPR032710|interpro:IPR004027(SEC-C motif)|interpro:IPR023006|interpro:IPR048469|refseq:YP_002347146.1|panther:PTHR33747(orthology-group)	"refseq:NP_001135787.1|refseq:NP_001135788.1|refseq:NP_005565.2|refseq:XP_005252978.1|ensembl:ENSG00000135363.12(gene)|ensembl:ENST00000395833.7(transcript)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR050945|mint:P25791|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:4KFZ|reactome:R-HSA-8939236|refseq:XP_016873216.1|refseq:XP_016873217.1|refseq:XP_016873218.1|refseq:XP_016873219.1|refseq:XP_016873220.1|refseq:XP_016873221.1|refseq:XP_016873222.1|panther:PTHR45787(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eDZPQNJ3f6IM09menY8ourrP8O0632	rogid:o3vD6A43ue8k3BhmFh/mgyYvhsw9606	intact-crc:C2D304FF0F15E759|rigid:Y1iWncdIp9IIWnCHGTFhyVR81Yc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H1K0	uniprotkb:A0A3G5LBG9	intact:EBI-1105310|uniprotkb:Q3KP30|uniprotkb:Q59EY8|uniprotkb:Q8NAQ1|uniprotkb:B4DWY8|uniprotkb:C9J4P5|ensembl:ENSP00000253699.3|ensembl:ENSP00000422551.1	intact:EBI-2843337|uniprotkb:Q7ARE7|uniprotkb:Q7BT22|uniprotkb:A0A1U8QL38|uniprotkb:O68742|uniprotkb:Q65AP5|uniprotkb:A0A2S9PDV0	psi-mi:rbns5_human(display_long)|uniprotkb:RBSN(gene name)|psi-mi:RBSN(display_short)|uniprotkb:110 kDa protein(gene name synonym)|uniprotkb:FYVE finger-containing Rab5 effector protein rabenosyn-5(gene name synonym)|uniprotkb:RAB effector RBSN(gene name synonym)|uniprotkb:ZFYVE20(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 20(gene name synonym)	psi-mi:a0a3g5lbg9_yerpe(display_long)|uniprotkb:YPMT1.25c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856433|imex:IM-13779-6108	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:675775""|efo:""Orphanet:675782""|ensembl:ENSG00000131381.13(gene)|ensembl:ENST00000253699.7(transcript)|ensembl:ENST00000476527.7(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR021565|interpro:IPR036531|interpro:IPR052727|mint:Q9H1K0|rcsb pdb:1YZM|rcsb pdb:1Z0J|rcsb pdb:1Z0K|reactome:R-HSA-168138|reactome:R-HSA-983231|refseq:NP_001289307.1|refseq:NP_071735.2|refseq:XP_005265441.1|refseq:XP_005265442.1|refseq:XP_016862512.1|panther:PTHR13510(orthology-group)"	refseq:NP_395361.1|refseq:YP_093902.1|refseq:NP_857661.1|refseq:WP_002211788.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fKkis2EhJdqQj04oUTABbwxEI2Y9606	rogid:b42FykicLMYhKQ/f+NviSJexojE632	intact-crc:EB2C00D62C569B95|rigid:IUaBnDvpZpXFLdWaDkc6VUJ8LGY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BWF3	uniprotkb:Q8Z9S7	intact:EBI-2856454|uniprotkb:B3KUN0|uniprotkb:Q8WU85|uniprotkb:Q6P1P2|uniprotkb:O02916|uniprotkb:Q4VC48|uniprotkb:B4E1U0|uniprotkb:E7EQS3|ensembl:ENSP00000309166.8|ensembl:ENSP00000386561.2|ensembl:ENSP00000386894.1	intact:EBI-2843785|uniprotkb:Q74PA2|uniprotkb:Q0W9R8|uniprotkb:Q8CZF5	psi-mi:rbm4_human(display_long)|uniprotkb:RBM4(gene name)|psi-mi:RBM4(display_short)|uniprotkb:RBM4A(gene name synonym)|uniprotkb:Lark homolog(gene name synonym)|uniprotkb:RNA-binding motif protein 4(gene name synonym)|uniprotkb:RNA-binding motif protein 4a(gene name synonym)	psi-mi:glmu_yerpe(display_long)|uniprotkb:glmU(gene name)|psi-mi:glmU(display_short)|uniprotkb:YPO4119(locus name)|uniprotkb:y4133(locus name)|uniprotkb:YP_4026(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856463|imex:IM-13779-6111	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001185772.1|refseq:NP_002887.2|refseq:NP_001185773.1|ensembl:ENSG00000173933.21(gene)|ensembl:ENST00000310092.12(transcript)|ensembl:ENST00000408993.6(transcript)|ensembl:ENST00000409406.1(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0002190""(cap-independent translational initiation)|go:""GO:0002192""(IRES-dependent translational initiation of linear mRNA)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016607""(nuclear speck)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030332""(cyclin binding)|go:""GO:0031016""(pancreas development)|go:""GO:0032055""(negative regulation of translation in response to stress)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0035198""(miRNA binding)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0035773""(insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0035883""(enteroendocrine cell differentiation)|go:""GO:0043153""(entrainment of circadian clock by photoperiod)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0046626""(regulation of insulin receptor signaling pathway)|go:""GO:0046685""(response to arsenic-containing substance)|go:""GO:0046822""(regulation of nucleocytoplasmic transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0097157""(pre-mRNA intronic binding)|go:""GO:0097158""(pre-mRNA intronic pyrimidine-rich binding)|go:""GO:0097167""(circadian regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979|interpro:IPR050502|mint:Q9BWF3|rcsb pdb:2DNQ|reactome:R-HSA-400253|dip:DIP-44199N|panther:PTHR23147(orthology-group)"	"rcsb pdb:4FCE|interpro:IPR029044|interpro:IPR005882(UDP-N-acetylglucosamine pyrophosphorylase)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR018357|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR025877|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003977""(UDP-N-acetylglucosamine diphosphorylase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019134""(glucosamine-1-phosphate N-acetyltransferase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR038009|refseq:WP_002215550.1|refseq:YP_002348970.1|interpro:IPR050065|panther:PTHR43584(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hbW6dv/AEWQz3mWvA2/9n8h/bbA9606	rogid:9qnSgGL+fCmXV2kMl5dYnODFWqw632	intact-crc:B562AB6847A111ED|rigid:nfNLeFmCvc2oCmVpkv95octwXdM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W7E2	uniprotkb:P78332	intact:EBI-2848155|uniprotkb:A0A2U2H0T1|uniprotkb:Q74QL8|uniprotkb:Q0WI49|uniprotkb:Q7CGN6|uniprotkb:A0A384KKB9	intact:EBI-2692323|uniprotkb:O75524|uniprotkb:O60549|uniprotkb:Q86SS3|uniprotkb:B4E0G6|ensembl:ENSP00000266022.4	psi-mi:a0a0h2w7e2_yerpe(display_long)|uniprotkb:iutA(gene name)|psi-mi:iutA(display_short)|uniprotkb:YPO0994(locus name)	psi-mi:rbm6_human(display_long)|uniprotkb:DEF3(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-12(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:RNA-binding motif protein 6(gene name synonym)|uniprotkb:RNA-binding protein DEF-3(gene name synonym)|uniprotkb:RBM6(gene name)|psi-mi:RBM6(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856447|imex:IM-13779-6112	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|refseq:WP_002211646.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002346039.1"	"refseq:NP_005768.1|refseq:NP_001161054.1|refseq:XP_005264843.1|refseq:XP_005264844.1|refseq:XP_016860988.1|refseq:XP_016860989.1|refseq:XP_016860990.1|refseq:XP_016860991.1|ensembl:ENSG00000004534.15(gene)|ensembl:ENST00000266022.9(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006396""(RNA processing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034123|interpro:IPR034125|interpro:IPR035617|interpro:IPR035979|interpro:IPR041591|mint:P78332|panther:PTHR13948(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h+zziPxtFmhqRng+3zCsRqmsI/M632	rogid:qNU439nvkG+dQNbzNI+F2JI3B049606	intact-crc:847668160C7D12F8|rigid:zMsaN0fT5Q1yGjAkMRJ5zF6QZPg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P78332	uniprotkb:Q8CZU2	intact:EBI-2692323|uniprotkb:O75524|uniprotkb:O60549|uniprotkb:Q86SS3|uniprotkb:B4E0G6|ensembl:ENSP00000266022.4	intact:EBI-2843382	psi-mi:rbm6_human(display_long)|uniprotkb:DEF3(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-12(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:RNA-binding motif protein 6(gene name synonym)|uniprotkb:RNA-binding protein DEF-3(gene name synonym)|uniprotkb:RBM6(gene name)|psi-mi:RBM6(display_short)	psi-mi:q8czu2_yerpe(display_long)|uniprotkb:yapH(gene name)|psi-mi:yapH(display_short)|uniprotkb:y3396(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856440|imex:IM-13779-6109	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005768.1|refseq:NP_001161054.1|refseq:XP_005264843.1|refseq:XP_005264844.1|refseq:XP_016860988.1|refseq:XP_016860989.1|refseq:XP_016860990.1|refseq:XP_016860991.1|ensembl:ENSG00000004534.15(gene)|ensembl:ENST00000266022.9(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006396""(RNA processing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034123|interpro:IPR034125|interpro:IPR035617|interpro:IPR035979|interpro:IPR041591|mint:P78332|panther:PTHR13948(orthology-group)"	"interpro:IPR024973|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0019867""(outer membrane)|interpro:IPR036709|interpro:IPR043990|interpro:IPR050909"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qNU439nvkG+dQNbzNI+F2JI3B049606	rogid:w2l6qUtIv4INNGQ9HeM84bFptXU632	intact-crc:27358F36B47BA5D9|rigid:ioM6cAy2WeypiOsQS4wjg2jakvA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96LT9	uniprotkb:P58475	intact:EBI-2602807|uniprotkb:Q96FK7|uniprotkb:Q96JI8|uniprotkb:Q9NXX2|uniprotkb:Q5TZ87|uniprotkb:Q9NSU7|uniprotkb:D3DT74|intact:EBI-28982482|uniprotkb:A8K1C9|ensembl:ENSP00000391432.1|ensembl:ENSP00000432886.1	intact:EBI-2844536|uniprotkb:Q0WD15	psi-mi:rnpc3_human(display_long)|uniprotkb:RNPC3(gene name)|psi-mi:RNPC3(display_short)|uniprotkb:KIAA1839(gene name synonym)|uniprotkb:RBM40(gene name synonym)|uniprotkb:RNP(gene name synonym)|uniprotkb:RNA-binding motif protein 40(gene name synonym)|uniprotkb:U11/U12 small nuclear ribonucleoprotein 65 kDa protein(gene name synonym)|uniprotkb:SNRNP65(gene name synonym)	psi-mi:pepb_yerpe(display_long)|uniprotkb:pepB(gene name)|psi-mi:pepB(display_short)|uniprotkb:Aminopeptidase B(gene name synonym)|uniprotkb:YPO2889(locus name)|uniprotkb:y1342(locus name)|uniprotkb:YP_2566(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856470|imex:IM-13779-6110	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000185946.16(gene)|ensembl:ENST00000423855.7(transcript)|ensembl:ENST00000533099.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005689""(U12-type spliceosomal complex)|go:""GO:0008380""(RNA splicing)|go:""GO:0030626""(U12 snRNA binding)|go:""GO:0097157""(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034147|interpro:IPR035979|interpro:IPR045164|mint:Q96LT9|rcsb pdb:3EGN|rcsb pdb:5OBN|reactome:R-HSA-72165|refseq:NP_060089.1|efo:""Orphanet:231662""|panther:PTHR16105(orthology-group)"	"rcsb pdb:6CXD|interpro:IPR008330(Peptidase M17, peptidase B)|interpro:IPR011356(Peptidase M17, leucyl aminopeptidase)|interpro:IPR000819(Peptidase M17, leucyl aminopeptidase, C-terminal)|go:""GO:0005737""(cytoplasm)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|refseq:WP_002209829.1|interpro:IPR047620|refseq:YP_002347823.1|panther:PTHR11963(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ehmZe1svzkhcslvywgnQ2MmcPD09606	rogid:J5OJKSDVSShLKMcWpyqc/Jwspys632	intact-crc:FB0BF131FF321B0B|rigid:/ms4qA2a+cRwqjNSnP0FUNK9Ikk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14498	uniprotkb:Q8ZHZ4	intact:EBI-395290|uniprotkb:A5D8W2|uniprotkb:B0BLV3|uniprotkb:Q14499|uniprotkb:A2RRD3|uniprotkb:E1P5S0|uniprotkb:E1P5S1|ensembl:ENSP00000253363.6	intact:EBI-2854831|uniprotkb:Q8CZT0|uniprotkb:Q74RJ0|uniprotkb:Q0WIU7	psi-mi:rbm39_human(display_long)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym)	psi-mi:flgi1_yerpe(display_long)|uniprotkb:flgI1(gene name)|psi-mi:flgI1(display_short)|uniprotkb:Basal body P-ring protein 1(gene name synonym)|uniprotkb:YPO0730(locus name)|uniprotkb:y3448(locus name)|uniprotkb:YP_3041(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856496|imex:IM-13779-6116	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229528.1|refseq:NP_001229529.1|refseq:NP_004893.1|refseq:NP_909122.1|ensembl:ENSG00000131051.24(gene)|ensembl:ENST00000253363.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006396""(RNA processing)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034451""(centriolar satellite)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0050733""(RS domain binding)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q14498|rcsb pdb:2JRS|rcsb pdb:2MHN|rcsb pdb:4OO6|rcsb pdb:4OZ0|rcsb pdb:4OZ1|rcsb pdb:4YUD|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:7Q33|reactome:R-HSA-72163|dip:DIP-32928N|panther:PTHR48036(orthology-group)"	"interpro:IPR001782(Flagellar P-ring protein)|go:""GO:0005198""(structural molecule activity)|go:""GO:0009428""(bacterial-type flagellum basal body, distal rod, P ring)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:YP_002345791.1|panther:PTHR30381(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:/e7HNZt0CtcDKTwF8BqSwNpyufc9606	rogid:SjQhgcbQkRdaN3B9eqXEc4t7H20632	intact-crc:949BAFAE21AF1A91|rigid:ZjAWsseHv5k9sCe40X2vWv8EmS0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14498	uniprotkb:A0A6B3VBG2	intact:EBI-395290|uniprotkb:A5D8W2|uniprotkb:B0BLV3|uniprotkb:Q14499|uniprotkb:A2RRD3|uniprotkb:E1P5S0|uniprotkb:E1P5S1|ensembl:ENSP00000253363.6	intact:EBI-2849663	psi-mi:rbm39_human(display_long)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym)	psi-mi:a0a6b3vbg2_yerpe(display_long)|uniprotkb:yapB(gene name)|psi-mi:yapB(display_short)|uniprotkb:y1345(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856489|imex:IM-13779-6117	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229528.1|refseq:NP_001229529.1|refseq:NP_004893.1|refseq:NP_909122.1|ensembl:ENSG00000131051.24(gene)|ensembl:ENST00000253363.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006396""(RNA processing)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034451""(centriolar satellite)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0050733""(RS domain binding)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q14498|rcsb pdb:2JRS|rcsb pdb:2MHN|rcsb pdb:4OO6|rcsb pdb:4OZ0|rcsb pdb:4OZ1|rcsb pdb:4YUD|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:7Q33|reactome:R-HSA-72163|dip:DIP-32928N|panther:PTHR48036(orthology-group)"	"interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|uniprotkb:A0A6B3T6Y5(uniprot-removed-ac)|go:""GO:0019867""(outer membrane)|interpro:IPR051551"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:/e7HNZt0CtcDKTwF8BqSwNpyufc9606	rogid:jNPx4rqCv9bEZelj7jbp42kW+NY632	intact-crc:35E0C482426FB7C7|rigid:N//mMjLzKyVm0qhKVZpDYjXKAGU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H0Z9	uniprotkb:Q8CZU9	intact:EBI-2840723|uniprotkb:A6NMU6|uniprotkb:A6NDK1|uniprotkb:Q9BYK3|uniprotkb:Q15350|uniprotkb:Q9BYK4|uniprotkb:Q15351|ensembl:ENSP00000348538.5	intact:EBI-2841714	psi-mi:rbm38_human(display_long)|uniprotkb:RBM38(gene name)|psi-mi:RBM38(display_short)|uniprotkb:RNPC1(gene name synonym)|uniprotkb:SEB4(gene name synonym)|uniprotkb:CLL-associated antigen KW-5(gene name synonym)|uniprotkb:HSRNASEB(gene name synonym)|uniprotkb:RNA-binding motif protein 38(gene name synonym)|uniprotkb:RNA-binding region-containing protein 1(gene name synonym)|uniprotkb:ssDNA-binding protein SEB4(gene name synonym)	psi-mi:q8czu9_yerpe(display_long)|uniprotkb:y3342(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856516|imex:IM-13779-6113	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_059965.2|refseq:NP_906270.1|refseq:NP_001278709.1|ensembl:ENSG00000132819.17(gene)|ensembl:ENST00000356208.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0006978""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008380""(RNA splicing)|go:""GO:0010830""(regulation of myotube differentiation)|go:""GO:0030154""(cell differentiation)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR050886|rcsb pdb:2CQD|rcsb pdb:6JVX|rcsb pdb:6JVY|panther:PTHR48024(orthology-group)"	interpro:IPR002491(Periplasmic binding protein)|interpro:IPR050902	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YRMebCG/7UAxjcg/UCoZSwnwMOg9606	rogid:61Vn/X9ZzrY6cGaSgyM0HeClZVc632	intact-crc:0C4B4C1C7D6CE405|rigid:i/XoRn56bLrMhP1AHd2CzLW48Z8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14498	uniprotkb:Q8ZAQ1	intact:EBI-395290|uniprotkb:A5D8W2|uniprotkb:B0BLV3|uniprotkb:Q14499|uniprotkb:A2RRD3|uniprotkb:E1P5S0|uniprotkb:E1P5S1|ensembl:ENSP00000253363.6	intact:EBI-2856477|uniprotkb:Q0WAR8	psi-mi:rbm39_human(display_long)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym)	psi-mi:thie_yerpe(display_long)|uniprotkb:thiE(gene name)|psi-mi:thiE(display_short)|uniprotkb:Thiamine-phosphate pyrophosphorylase(gene name synonym)|uniprotkb:YPO3740(locus name)|uniprotkb:YP_3103(locus name)|uniprotkb:y0490(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856482|imex:IM-13779-6114	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229528.1|refseq:NP_001229529.1|refseq:NP_004893.1|refseq:NP_909122.1|ensembl:ENSG00000131051.24(gene)|ensembl:ENST00000253363.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006396""(RNA processing)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034451""(centriolar satellite)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0050733""(RS domain binding)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q14498|rcsb pdb:2JRS|rcsb pdb:2MHN|rcsb pdb:4OO6|rcsb pdb:4OZ0|rcsb pdb:4OZ1|rcsb pdb:4YUD|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:7Q33|reactome:R-HSA-72163|dip:DIP-32928N|panther:PTHR48036(orthology-group)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR022998|interpro:IPR034291|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004789""(thiamine-phosphate diphosphorylase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|interpro:IPR036206|refseq:YP_002348620.1|panther:PTHR20857(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:/e7HNZt0CtcDKTwF8BqSwNpyufc9606	rogid:ZNe5XLgZFr9Sfzn/Uc33alfe1gA632	intact-crc:0BB656AE2082184C|rigid:MK89B+czLTptjYzI0JbqGIdXWdA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0P1	uniprotkb:Q14498	intact:EBI-2856506|uniprotkb:Q8ZFL9|uniprotkb:Q0WGA3	intact:EBI-395290|uniprotkb:A5D8W2|uniprotkb:B0BLV3|uniprotkb:Q14499|uniprotkb:A2RRD3|uniprotkb:E1P5S0|uniprotkb:E1P5S1|ensembl:ENSP00000253363.6	psi-mi:chey_yerpe(display_long)|uniprotkb:cheY(gene name)|psi-mi:cheY(display_short)|uniprotkb:YPO1680(locus name)|uniprotkb:y1842(locus name)|uniprotkb:YP_1810(locus name)	psi-mi:rbm39_human(display_long)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856503|imex:IM-13779-6115	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q8D0P1|interpro:IPR011006(CheY-like)|interpro:IPR001789(Signal transduction response regulator, receiver region)|refseq:WP_002210873.1|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|interpro:IPR052048|refseq:YP_002346685.1|panther:PTHR43228(orthology-group)"	"refseq:NP_001229528.1|refseq:NP_001229529.1|refseq:NP_004893.1|refseq:NP_909122.1|ensembl:ENSG00000131051.24(gene)|ensembl:ENST00000253363.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006396""(RNA processing)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034451""(centriolar satellite)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0050733""(RS domain binding)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q14498|rcsb pdb:2JRS|rcsb pdb:2MHN|rcsb pdb:4OO6|rcsb pdb:4OZ0|rcsb pdb:4OZ1|rcsb pdb:4YUD|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:7Q33|reactome:R-HSA-72163|dip:DIP-32928N|panther:PTHR48036(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:wf5r24m07Zgglm31fBnlvBt1VVY632	rogid:/e7HNZt0CtcDKTwF8BqSwNpyufc9606	intact-crc:6DF8841020825619|rigid:4qH7fS0ufCzK6sz/46PRE44jC+U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06400	uniprotkb:Q8ZC49	intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163.4	intact:EBI-2852010|uniprotkb:Q0WCB0	psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:thii_yerpe(display_long)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:YPO3173(locus name)|uniprotkb:y1012(locus name)|uniprotkb:YP_0758(locus name)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856549|imex:IM-13779-6121	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000139687.17(gene)|ensembl:ENST00000267163.6(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001894""(tissue homeostasis)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016605""(PML body)|go:""GO:0019900""(kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031134""(sister chromatid biorientation)|go:""GO:0031175""(neuron projection development)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034088""(maintenance of mitotic sister chromatid cohesion)|go:""GO:0034349""(glial cell apoptotic process)|go:""GO:0035189""(Rb-E2F complex)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0042551""(neuron maturation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043353""(enucleate erythrocyte differentiation)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043550""(regulation of lipid kinase activity)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0045842""(positive regulation of mitotic metaphase/anaphase transition)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048565""(digestive tract development)|go:""GO:0048667""(cell morphogenesis involved in neuron differentiation)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051276""(chromosome organization)|go:""GO:0051301""(cell division)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0061793""(chromatin lock complex)|go:""GO:0071459""(protein localization to chromosome, centromeric region)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071901""(negative regulation of protein serine/threonine kinase activity)|go:""GO:0090230""(regulation of centromere complex assembly)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902948""(negative regulation of tau-protein kinase activity)|go:""GO:1903055""(positive regulation of extracellular matrix organization)|go:""GO:1903944""(negative regulation of hepatocyte apoptotic process)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904761""(negative regulation of myofibroblast differentiation)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000679""(positive regulation of transcription regulatory region DNA binding)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|reactome:R-HSA-9725371|reactome:R-HSA-9841922|refseq:NP_000312.2|efo:""Orphanet:1587""|efo:""Orphanet:357027""|efo:""Orphanet:357034""|efo:""Orphanet:668""|efo:""Orphanet:70573""|dip:DIP-582N|panther:PTHR13742(orthology-group)|ensembl:ENSP00000267163.4"	"interpro:IPR026340|interpro:IPR001763(Rhodanese-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|refseq:WP_002208658.1|go:""GO:0000049""(tRNA binding)|go:""GO:0002937""(tRNA 4-thiouridine biosynthesis)|go:""GO:0004810""(CCA tRNA nucleotidyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0052837""(thiazole biosynthetic process)|go:""GO:0140741""(tRNA-uracil-4 sulfurtransferase activity)|interpro:IPR036873|interpro:IPR054173|refseq:YP_002348078.1|interpro:IPR049961|interpro:IPR049962|interpro:IPR050102|panther:PTHR43209(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/12	rogid:xidCNX96KlQzu160polvT61k4Zw9606	rogid:JVdYYtaSxHT0xyr6zYDRPl2jCF4632	intact-crc:C71098644E29175F|rigid:/i5T7UDRWvN7UL7aa48n01IIpmk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CWG4	uniprotkb:Q9NW64	intact:EBI-2856530|uniprotkb:Q74QZ9	intact:EBI-2602260|uniprotkb:A6NDM5|uniprotkb:O95607|uniprotkb:B4DLI9|ensembl:ENSP00000199814.4	psi-mi:q8cwg4_yerpe(display_long)|uniprotkb:glpD(gene name)|psi-mi:glpD(display_short)|uniprotkb:YP_3299(locus name)|uniprotkb:y3891(locus name)	psi-mi:rbm22_human(display_long)|uniprotkb:RBM22(gene name)|psi-mi:RBM22(display_short)|uniprotkb:ZC3H16(gene name synonym)|uniprotkb:RNA-binding motif protein 22(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 16(gene name synonym)|uniprotkb:199G4(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856535|imex:IM-13779-6119	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR031656|go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0006072""(glycerol-3-phosphate metabolic process)|go:""GO:0009331""(""glycerol-3-phosphate dehydrogenase (FAD) complex"")|interpro:IPR038299|interpro:IPR036188"	"refseq:NP_060517.1|ensembl:ENSG00000086589.12(gene)|ensembl:ENST00000199814.9(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000974""(Prp19 complex)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0033120""(positive regulation of RNA splicing)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0045292""(mRNA cis splicing, via spliceosome)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0046872""(metal ion binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0071006""(U2-type catalytic step 1 spliceosome)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036855|interpro:IPR039171|interpro:IPR048995|mint:Q9NW64|rcsb pdb:2YTC|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8RO2|rcsb pdb:9FMD|reactome:R-HSA-72163|panther:PTHR14089(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:R9I22ZXVmXiKYYz/+NgwNjlHCb0632	rogid:PjcPER8I/RBxwu3oACO1LHxzKAM9606	intact-crc:EB01CFB9D656C41D|rigid:Bi9Cz4zzMp3GuSqiMELMAWktGuc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H077	uniprotkb:Q9H0Z9	intact:EBI-2841812|uniprotkb:Q74VJ9|uniprotkb:A0A384LD89|uniprotkb:Q0WHC7|uniprotkb:Q7CHD8|uniprotkb:A0A380PPP8	intact:EBI-2840723|uniprotkb:A6NMU6|uniprotkb:A6NDK1|uniprotkb:Q9BYK3|uniprotkb:Q15350|uniprotkb:Q9BYK4|uniprotkb:Q15351|ensembl:ENSP00000348538.5	psi-mi:a0a2u2h077_yerpe(display_long)|uniprotkb:mtr(gene name)|psi-mi:mtr(display_short)|uniprotkb:YPO1285(locus name)	psi-mi:rbm38_human(display_long)|uniprotkb:RBM38(gene name)|psi-mi:RBM38(display_short)|uniprotkb:RNPC1(gene name synonym)|uniprotkb:SEB4(gene name synonym)|uniprotkb:CLL-associated antigen KW-5(gene name synonym)|uniprotkb:HSRNASEB(gene name synonym)|uniprotkb:RNA-binding motif protein 38(gene name synonym)|uniprotkb:RNA-binding region-containing protein 1(gene name synonym)|uniprotkb:ssDNA-binding protein SEB4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856523|imex:IM-13779-6118	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018227|interpro:IPR013059(Tryptophan/tyrosine transporter)|interpro:IPR006311(Twin-arginine translocation pathway signal)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005886""(plasma membrane)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|refseq:YP_002346311.1|refseq:WP_002208812.1"	"refseq:NP_059965.2|refseq:NP_906270.1|refseq:NP_001278709.1|ensembl:ENSG00000132819.17(gene)|ensembl:ENST00000356208.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0006978""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008380""(RNA splicing)|go:""GO:0010830""(regulation of myotube differentiation)|go:""GO:0030154""(cell differentiation)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR050886|rcsb pdb:2CQD|rcsb pdb:6JVX|rcsb pdb:6JVY|panther:PTHR48024(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M4JTYX328BR2JznjfkTVzEKmmW4632	rogid:YRMebCG/7UAxjcg/UCoZSwnwMOg9606	intact-crc:F01939DB3A36CCD2|rigid:uIKCo0YPntKwUhwQiSC+TAzgqtc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08999	uniprotkb:Q9X6B0	intact:EBI-971439|ensembl:ENSP00000262133.6|uniprotkb:Q15073|uniprotkb:Q16084|uniprotkb:Q92812|uniprotkb:B7Z913|uniprotkb:Q8NE70	intact:EBI-2844324|intact:EBI-2856296|uniprotkb:Q0WBX3	psi-mi:rbl2_human(display_long)|uniprotkb:RBL2(gene name)|psi-mi:RBL2(display_short)|uniprotkb:RB2(gene name synonym)|uniprotkb:Retinoblastoma-related protein 2(gene name synonym)|uniprotkb:130 kDa retinoblastoma-associated protein(gene name synonym)|uniprotkb:pRb2(gene name synonym)	psi-mi:katg_yerpe(display_long)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)|uniprotkb:katY(gene name synonym)|uniprotkb:Antigen 5(gene name synonym)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:YPO3319(locus name)|uniprotkb:y0870(locus name)|uniprotkb:YP_0367(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856542|imex:IM-13779-6122	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000103479.17(gene)|ensembl:ENST00000262133.11(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0030154""(cell differentiation)|go:""GO:0043550""(regulation of lipid kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:Q08999|rcsb pdb:4XI9|rcsb pdb:5C1D|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-9617828|refseq:NP_005602.3|refseq:NP_001310537.1|dip:DIP-425N|panther:PTHR13742(orthology-group)"	"interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|go:""GO:0004096""(catalase activity)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|refseq:WP_002209433.1|refseq:YP_002348215.1|panther:PTHR30555(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/17	rogid:2/u/ejPv7UkPWeZYyfJpZXf9Roc9606	rogid:RBebELhpxkVGfQv9Ix9rW4jzmpE632	intact-crc:7870657461E8C23C|rigid:vkNJgRRQ7gC7Yyo7tRONS+UzIOM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0N7	uniprotkb:Q9Y3P9	intact:EBI-2846144|uniprotkb:Q74UI7	intact:EBI-1057545|uniprotkb:Q05CW2|uniprotkb:Q6ZMY1|uniprotkb:Q9HA28|uniprotkb:Q9P0E2|uniprotkb:Q9UG67|intact:EBI-2948690|uniprotkb:B9A6L2|ensembl:ENSP00000362751.4	psi-mi:q8d0n7_yerpe(display_long)|uniprotkb:prc(gene name)|psi-mi:prc(display_short)|uniprotkb:y1867(locus name)|uniprotkb:YP_1730(locus name)	psi-mi:rbgp1_human(display_long)|uniprotkb:RABGAP1(gene name)|psi-mi:RABGAP1(display_short)|uniprotkb:HSPC094(orf name)|uniprotkb:Rab6 GTPase-activating protein GAPCenA(gene name synonym)|uniprotkb:GAP and centrosome-associated protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856556|imex:IM-13779-6120	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR040573|interpro:IPR005151(Peptidase S41)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004447(Peptidase S41A, C-terminal protease)|interpro:IPR020992|interpro:IPR029045|go:""GO:0006508""(proteolysis)|go:""GO:0008236""(serine-type peptidase activity)|interpro:IPR036034"	"refseq:NP_036329.3|refseq:XP_011516742.1|refseq:XP_011516743.1|refseq:XP_016870056.1|refseq:XP_016870057.1|refseq:XP_016870058.1|ensembl:ENSG00000011454.18(gene)|ensembl:ENST00000373647.9(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0015631""(tubulin binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043087""(regulation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022164|interpro:IPR035969|interpro:IPR050302|mint:Q9Y3P9|rcsb pdb:4NC6|reactome:R-HSA-8854214|panther:PTHR47219(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Elwv+8dvBsFzE8ij0VVewq9UzrA632	rogid:yGnx7q5tyqYfpbeVDwZ8IKI1o+k9606	intact-crc:C66C8D36223A9A23|rigid:kcxwigQk07OBBLIZeQG4xllgFEs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TDY2	uniprotkb:Q8ZEX9	intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008.5	intact:EBI-2841177|uniprotkb:Q0WFD6	psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym)	psi-mi:hem1_yerpe(display_long)|uniprotkb:hemA(gene name)|psi-mi:hemA(display_short)|uniprotkb:YPO2016(locus name)|uniprotkb:y2291(locus name)|uniprotkb:YP_1864(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856563|imex:IM-13779-6123	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_016869596.1|ensembl:ENSG00000023287.13(gene)|ensembl:ENST00000025008.10(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0000425""(pexophagy)|go:""GO:0001889""(liver development)|go:""GO:0005764""(lysosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0007507""(heart development)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0034517""(ribophagy)|go:""GO:0034727""(piecemeal microautophagy of the nucleus)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045087""(innate immune response)|go:""GO:0045793""(positive regulation of cell size)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061709""(reticulophagy)|go:""GO:0061723""(glycophagy)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:1903059""(regulation of protein lipidation)|go:""GO:1990316""(Atg1/ULK1 kinase complex)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|rcsb pdb:7EA2|rcsb pdb:7EAA|rcsb pdb:8SOI|rcsb pdb:8SQZ|rcsb pdb:8SRM|rcsb pdb:8W6B|rcsb pdb:8YFK|rcsb pdb:8YFL|rcsb pdb:8YFM|rcsb pdb:8YFN|rcsb pdb:9C82|reactome:R-HSA-1632852|refseq:XP_011515945.1|dip:DIP-45969N|panther:PTHR13222(orthology-group)"	"refseq:YP_002347002.1|interpro:IPR000343(Tetrapyrrole biosynthesis, glutamyl-tRNA reductase)|interpro:IPR015896(Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, C-terminal)|interpro:IPR015895(Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal)|interpro:IPR018214|interpro:IPR006151(Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase)|go:""GO:0008883""(glutamyl-tRNA reductase activity)|go:""GO:0019353""(protoporphyrinogen IX biosynthetic process from glutamate)|go:""GO:0050661""(NADP binding)|refseq:WP_002211237.1|interpro:IPR036291|interpro:IPR036343|interpro:IPR036453|panther:PTHR43013(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606	rogid:gC8jpCVOJdbcbVGI/m53CULDe6w632	intact-crc:B902206C4598DDA2|rigid:F1/8TZeF1sJnUAC63F8NqmzND8s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P51159	uniprotkb:Q8D0R5	intact:EBI-716881|uniprotkb:O00195|uniprotkb:Q6FI40|uniprotkb:Q9UIR9|uniprotkb:Q9Y5U3|ensembl:ENSP00000337761.1|ensembl:ENSP00000379601.2|ensembl:ENSP00000455012.1|ensembl:ENSP00000456059.1|ensembl:ENSP00000513368.1|ensembl:ENSP00000513369.1	intact:EBI-2850346|uniprotkb:Q74T91	psi-mi:rb27a_human(display_long)|uniprotkb:GTP-binding protein Ram(gene name synonym)|uniprotkb:RAB27A(gene name)|psi-mi:RAB27A(display_short)|uniprotkb:RAB27(gene name synonym)	psi-mi:q8d0r5_yerpe(display_long)|uniprotkb:cpsG(gene name)|psi-mi:cpsG(display_short)|uniprotkb:y1710(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856570|imex:IM-13779-6126	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-44244N|ensembl:ENSG00000069974.17(gene)|ensembl:ENST00000336787.6(transcript)|ensembl:ENST00000396307.6(transcript)|ensembl:ENST00000564609.5(transcript)|ensembl:ENST00000569493.5(transcript)|ensembl:ENST00000697642.1(transcript)|ensembl:ENST00000697643.1(transcript)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006887""(exocytosis)|go:""GO:0007596""(blood coagulation)|go:""GO:0009306""(protein secretion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019003""(GDP binding)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030141""(secretory granule)|go:""GO:0030318""(melanocyte differentiation)|go:""GO:0030425""(dendrite)|go:""GO:0031489""(myosin V binding)|go:""GO:0032400""(melanosome localization)|go:""GO:0032402""(melanosome transport)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0033162""(melanosome membrane)|go:""GO:0035580""(specific granule lumen)|go:""GO:0036257""(multivesicular body organization)|go:""GO:0042470""(melanosome)|go:""GO:0043316""(cytotoxic T cell degranulation)|go:""GO:0043320""(natural killer cell degranulation)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070382""(exocytic vesicle)|go:""GO:0071985""(multivesicular body sorting pathway)|go:""GO:0097278""(complement-dependent cytotoxicity)|go:""GO:1903307""(positive regulation of regulated secretory pathway)|go:""GO:1903428""(positive regulation of reactive oxygen species biosynthetic process)|go:""GO:1903435""(positive regulation of constitutive secretory pathway)|go:""GO:1990182""(exosomal secretion)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|interpro:IPR050305|mint:P51159|rcsb pdb:6HUF|rcsb pdb:7OPP|rcsb pdb:7OPQ|rcsb pdb:7OPR|reactome:R-HSA-264876|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9824585|refseq:NP_004571.2|refseq:NP_899057.1|refseq:NP_899058.1|refseq:NP_899059.1|refseq:XP_005254633.1|refseq:XP_011520154.1|refseq:XP_011520156.1|refseq:XP_011520157.1|refseq:XP_011520158.1|efo:""Orphanet:79477""|panther:PTHR47977(orthology-group)"	"interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016868""(intramolecular phosphotransferase activity)|interpro:IPR036900"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xHjWV0BbHEEl7KwP1IWzMV7WRuE9606	rogid:z2kz1BX3Sd7E73WGqRSF6X0AGrM632	intact-crc:310AC5A3B5A132CF|rigid:ar3r4cpEHwkcGQpeOECWz2uXpWI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PLH1	uniprotkb:Q8WWW0	intact:EBI-2856592|uniprotkb:Q74X46|uniprotkb:Q7CKH1|uniprotkb:A0A0H2W2R5	intact:EBI-367390|uniprotkb:Q5SY32|uniprotkb:Q8WWV9|uniprotkb:Q8WXF4|uniprotkb:Q9BT99|uniprotkb:A8K1E6|ensembl:ENSP00000462099.1	psi-mi:a0a2s9plh1_yerpe(display_long)|uniprotkb:YPO3468(locus name)	psi-mi:rasf5_human(display_long)|uniprotkb:RAPL(gene name synonym)|uniprotkb:RASSF5(gene name)|psi-mi:RASSF5(display_short)|uniprotkb:NORE1(gene name synonym)|uniprotkb:New ras effector 1(gene name synonym)|uniprotkb:Regulator for cell adhesion and polarization enriched in lymphoid tissues(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856589|imex:IM-13779-6125	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002209281.1|interpro:IPR008397(Alginate lyase)|interpro:IPR008929(Chondroitin AC/alginate lyase)|go:""GO:0016829""(lyase activity)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348357.1"	"refseq:NP_872604.1|refseq:NP_872605.1|refseq:NP_872606.1|ensembl:ENSG00000266094.8(gene)|ensembl:ENST00000579436.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005874""(microtubule)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0042802""(identical protein binding)|go:""GO:0046651""(lymphocyte proliferation)|go:""GO:0046872""(metal ion binding)|go:""GO:0050672""(negative regulation of lymphocyte proliferation)|go:""GO:1900180""(regulation of protein localization to nucleus)|interpro:IPR000159(Ras-association)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011524(SARAH)|interpro:IPR029071|interpro:IPR033614|interpro:IPR033623|interpro:IPR046349|mint:Q8WWW0|rcsb pdb:4LGD|rcsb pdb:4OH8|dip:DIP-32490N|panther:PTHR22738(orthology-group)|ensembl:ENST00000577571.5|ensembl:ENSP00000462576.1|ensembl:ENSP00000462099.1|ensembl:ENST00000580449.5|ensembl:ENSP00000462544.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XJauDb6vvXdcLKHXeXt+Js2URk8632	rogid:EqQpr1Zt1laHo0Y23CpTVMnl28Y9606	intact-crc:1B0FEF8F16726EB2|rigid:/KM8+tWZ4lIVR0eYhLu70c4as/U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86WH2	uniprotkb:Q8ZI61	intact:EBI-2845202|uniprotkb:Q86WH1|ensembl:ENSP00000443021.1	intact:EBI-2856600|uniprotkb:Q0WJ17|uniprotkb:Q8CZR9|uniprotkb:Q74RQ4	psi-mi:rasf3_human(display_long)|uniprotkb:RASSF3(gene name)|psi-mi:RASSF3(display_short)	"psi-mi:glne_yerpe(display_long)|uniprotkb:glnE(gene name)|psi-mi:glnE(display_short)|uniprotkb:""ATP:glutamine synthetase adenylyltransferase""(gene name synonym)|uniprotkb:ATase(gene name synonym)|uniprotkb:YPO0653(locus name)|uniprotkb:YP_2968(locus name)|uniprotkb:y3525(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856607|imex:IM-13779-6127	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_835463.1|ensembl:ENSG00000153179.14(gene)|ensembl:ENST00000542104.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0042802""(identical protein binding)|interpro:IPR000159(Ras-association)|interpro:IPR011524(SARAH)|interpro:IPR029071|interpro:IPR033614|panther:PTHR22738(orthology-group)|ensembl:ENST00000283172.8|ensembl:ENSP00000283172.4|ensembl:ENSP00000443021.1"	"interpro:IPR023057|interpro:IPR005190(Glutamate-ammonia ligase adenylyltransferase)|interpro:IPR013546(GlnD PII-uridylyltransferase)|refseq:WP_002212194.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000820""(regulation of glutamine family amino acid metabolic process)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008882""([glutamate-ammonia-ligase] adenylyltransferase activity)|go:""GO:0047388""([glutamine synthetase]-adenylyl-L-tyrosine phosphorylase activity)|interpro:IPR043519|refseq:YP_002345721.1|panther:PTHR30621(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ipKVrUCmMEXZqFafYvRKKqY6qsg9606	rogid:RoEcJZfF/CSIgmtP9TYrZ6mEC70632	intact-crc:C8842696B9407529|rigid:UlqPOL8mUvckW2nawWwWJZ6DWRw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q02833	uniprotkb:Q8D0P9	intact:EBI-929013|uniprotkb:Q3KP42|uniprotkb:G5E9N9|uniprotkb:Q3KP41|intact:EBI-11052282|ensembl:ENSP00000380713.3|ensembl:ENSP00000479652.1	intact:EBI-2856577|uniprotkb:Q74UF2	psi-mi:rasf7_human(display_long)|uniprotkb:RASSF7(gene name)|psi-mi:RASSF7(display_short)|uniprotkb:C11orf13(gene name synonym)|uniprotkb:HRC1(gene name synonym)|uniprotkb:HRAS1-related cluster protein 1(gene name synonym)	psi-mi:q8d0p9_yerpe(display_long)|uniprotkb:aer(gene name)|psi-mi:aer(display_short)|uniprotkb:YP_1774(locus name)|uniprotkb:y1805(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856582|imex:IM-13779-6124	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137465.1|refseq:NP_001137466.1|refseq:NP_003466.1|refseq:XP_016873850.1|refseq:XP_016873851.1|ensembl:ENSG00000099849.15(gene)|ensembl:ENSG00000273859.4(gene)|ensembl:ENST00000397583.8(transcript)|ensembl:ENST00000622905.2(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0034451""(centriolar satellite)|interpro:IPR000159(Ras-association)|interpro:IPR029071|interpro:IPR033593|interpro:IPR033631|mint:Q02833|ensembl:ENST00000397582.7|ensembl:ENSP00000380712.3|ensembl:ENSP00000380713.3|ensembl:ENST00000431809.5|ensembl:ENSP00000403068.1|ensembl:ENST00000454668.2|ensembl:ENSP00000405606.2|ensembl:ENSP00000479652.1|panther:PTHR15286(orthology-group)"	"interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR051310|interpro:IPR013655(PAS fold-3)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR035965"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:p1j9prChoZIecLZDG02TGJ0Z76I9606	rogid:UQ1nmynYyPCB+ni3UxBTbLxoRNg632	intact-crc:CC3F9C341F30DF37|rigid:N+ftZgIzbOo0v6m1sLBQaYNyfGk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GXB6	uniprotkb:Q5U651	intact:EBI-2842443|uniprotkb:Q0WGI3|uniprotkb:Q74TC4|uniprotkb:Q7CJ25|uniprotkb:A0A0H2W4P6|uniprotkb:A0A384KVT4	intact:EBI-2797123|ensembl:ENSP00000222145.3|uniprotkb:Q6U676	psi-mi:a0a2u2gxb6_yerpe(display_long)|uniprotkb:23S rRNA accumulation protein YceD(gene name synonym)|uniprotkb:YPO1594(locus name)	psi-mi:rain_human(display_long)|uniprotkb:RASIP1(gene name)|psi-mi:RASIP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856635|imex:IM-13779-6129	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003772(Protein of unknown function DUF177)|interpro:IPR039255|go:""GO:0042254""(ribosome biogenesis)|refseq:WP_002210930.1|refseq:YP_002346605.1"	"ensembl:ENSG00000105538.10(gene)|ensembl:ENST00000222145.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0005795""(Golgi stack)|go:""GO:0005911""(cell-cell junction)|go:""GO:0007165""(signal transduction)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033625""(positive regulation of integrin activation)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0051020""(GTPase binding)|go:""GO:1905709""(negative regulation of membrane permeability)|go:""GO:2000299""(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR000159(Ras-association)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR037983|interpro:IPR052072|rcsb pdb:5KHO|rcsb pdb:5KHQ|dip:DIP-29457N|refseq:NP_060275.2|panther:PTHR16027(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	crc64:470021F91B59EC52	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:GDUDakEOgj5J/WN78nZbu71zTZY632	rogid:L0Vu21+1Ec4kZs0C89QTTABdvnA9606	intact-crc:936622CB58218D00|rigid:YID7tU/UTE1b8+fWtuUlNUh/lYk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3L5	uniprotkb:A0A3N4B418	intact:EBI-2856617|uniprotkb:B3KWD6|uniprotkb:Q5H9H9|uniprotkb:Q9BTS0|ensembl:ENSP00000340274.2|ensembl:ENSP00000359911.1	intact:EBI-2840046|uniprotkb:Q0WFD2|uniprotkb:Q74U73|uniprotkb:Q7CIA4|uniprotkb:A0A380PD11	psi-mi:rap2c_human(display_long)|uniprotkb:RAP2C(gene name)|psi-mi:RAP2C(display_short)	psi-mi:a0a3n4b418_yerpe(display_long)|uniprotkb:YPO2020(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856614|imex:IM-13779-6130	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011529678.1|refseq:NP_067006.3|refseq:NP_001258116.1|refseq:NP_001258115.1|ensembl:ENSG00000123728.10(gene)|ensembl:ENST00000342983.6(transcript)|ensembl:ENST00000370874.2(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0019003""(GDP binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0032486""(Rap protein signal transduction)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061097""(regulation of protein tyrosine kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090557""(establishment of endothelial intestinal barrier)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR041840|mint:Q9Y3L5|reactome:R-HSA-6798695|panther:PTHR24070(orthology-group)"	refseq:YP_002347006.1|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032698|refseq:WP_002211233.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sJd/ACUSylvly87sdRNcZUiF91k9606	rogid:wzxT1bjS3dgwqWVrMmCge2eTVT0632	intact-crc:0BCB1B8AD84E5E50|rigid:kwzmahQi30Kg6tABYIb0BwaiAXA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WKG1	uniprotkb:Q86V87	intact:EBI-2855083|uniprotkb:Q74Y36|uniprotkb:A0A0H2W137|uniprotkb:A0A3N4AZM6|uniprotkb:Q7CFW7|uniprotkb:A0A384L9U0	intact:EBI-2856645|uniprotkb:Q71JB5|uniprotkb:B3KNX1|uniprotkb:Q7L3J6|uniprotkb:Q9H6W4|uniprotkb:B2RDQ5|uniprotkb:Q969T0|uniprotkb:Q2M211|ensembl:ENSP00000289921.6|ensembl:ENSP00000403288.3	psi-mi:q0wkg1_yerpe(display_long)|uniprotkb:YPO0141(locus name)	psi-mi:fhi2b_human(display_long)|uniprotkb:FHIP2B(gene name)|psi-mi:FHIP2B(display_short)|uniprotkb:FAM160B2(gene name synonym)|uniprotkb:RAI16(gene name synonym)|uniprotkb:Retinoic acid-induced protein 16(gene name synonym)|uniprotkb:FP13191(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856642|imex:IM-13779-6131	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|refseq:WP_002208909.1|go:""GO:0046872""(metal ion binding)|interpro:IPR050155|interpro:IPR036412|refseq:YP_002345227.1"	refseq:NP_073586.5|ensembl:ENSG00000158863.22(gene)|ensembl:ENST00000289921.8(transcript)|ensembl:ENST00000450006.7(transcript)|interpro:IPR019384|interpro:IPR045668|interpro:IPR045669|panther:PTHR21705(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:C2n5rHIofpB8tAA4iKdS/lm5nZ4632	rogid:NM/AO5FsDbZMx7KR84w6yryM3nU9606	intact-crc:C0D864E62606DEAE|rigid:pgnwUGC/qbq4MP9q+aj1hmwNNxI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA76	uniprotkb:P61224	intact:EBI-2846943|uniprotkb:Q0WA76	intact:EBI-358143|intact:EBI-1047928|uniprotkb:P09526|uniprotkb:Q6DCA1|uniprotkb:Q6LES0|uniprotkb:Q502X3|uniprotkb:Q5TZR4|uniprotkb:B2R5Z2|ensembl:ENSP00000250559.9|ensembl:ENSP00000377085.5|ensembl:ENSP00000439966.1|ensembl:ENSP00000441275.1|uniprotkb:B4DQI8|uniprotkb:B4DW74|uniprotkb:B4DW94|intact:EBI-11037134|intact:EBI-21353832	psi-mi:glgx_yerpe(display_long)|uniprotkb:glgX(gene name)|psi-mi:glgX(display_short)|uniprotkb:Limit dextrin alpha-1,6-maltotetraose-hydrolase(gene name synonym)|uniprotkb:YPO3941(locus name)|uniprotkb:YP_3303(locus name)|uniprotkb:y3887(locus name)	psi-mi:rap1b_human(display_long)|uniprotkb:OK/SW-cl.11(orf name)|uniprotkb:RAP1B(gene name)|psi-mi:RAP1B(display_short)|uniprotkb:GTP-binding protein smg p21B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856628|imex:IM-13779-6128	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR022844|interpro:IPR011837(Glycogen debranching enzyme GlgX)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR040784|go:""GO:0004133""(obsolete glycogen debranching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005980""(glycogen catabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_002209499.1|interpro:IPR044505|refseq:YP_002348812.1|panther:PTHR43002(orthology-group)"	"panther:PTHR24070(orthology-group)|refseq:NP_001010942.1|refseq:NP_056461.1|ensembl:ENSG00000127314.18(gene)|ensembl:ENST00000250559.14(transcript)|ensembl:ENST00000341355.9(transcript)|ensembl:ENST00000393436.9(transcript)|ensembl:ENST00000537460.5(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0019003""(GDP binding)|go:""GO:0032486""(Rap protein signal transduction)|go:""GO:0033625""(positive regulation of integrin activation)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045955""(negative regulation of calcium ion-dependent exocytosis)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0061028""(establishment of endothelial barrier)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099010""(modification of postsynaptic structure)|go:""GO:1901888""(regulation of cell junction assembly)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000301""(negative regulation of synaptic vesicle exocytosis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR038851|mint:P61224|rcsb pdb:3BRW|rcsb pdb:3CF6|rcsb pdb:4DXA|rcsb pdb:4HDO|rcsb pdb:4HDQ|rcsb pdb:4M8N|rcsb pdb:4MGI|rcsb pdb:4MGK|rcsb pdb:4MGY|rcsb pdb:4MGZ|rcsb pdb:4MH0|rcsb pdb:5KHO|rcsb pdb:6AXF|rcsb pdb:6BA6|rcsb pdb:6KYK|rcsb pdb:6OQ3|rcsb pdb:6OQ4|rcsb pdb:6UZK|rcsb pdb:7C7I|rcsb pdb:7C7J|rcsb pdb:8SU8|rcsb pdb:8T09|rcsb pdb:8T7V|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-392517|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8875555|reactome:R-HSA-8950505|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_001238846.1|refseq:NP_001238847.1|refseq:NP_001238850.1|refseq:NP_001238851.1|dip:DIP-35407N|ensembl:ENSP00000250559.9|ensembl:ENSP00000441275.1|ensembl:ENSP00000377085.5|ensembl:ENST00000450214.6|ensembl:ENSP00000399986.2|ensembl:ENSP00000439966.1|ensembl:ENST00000539091.5|ensembl:ENSP00000444830.1|ensembl:ENST00000540209.5|ensembl:ENSP00000446318.1|ensembl:ENST00000542145.5|ensembl:ENSP00000440014.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:8sHtj0obGqvrIdGE1JWk8okcbRM632	rogid:CiuN7je+CaRH9QKDiR3vrzcJ87g9606	intact-crc:E0D03E940FB1E0E0|rigid:0k98PB7MK/4NEBszOZmYRK4iIHw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P0K7	uniprotkb:A0A5P8YF73	intact:EBI-1023749|uniprotkb:Q6V1W9|uniprotkb:Q7Z5I4|uniprotkb:Q7Z733|uniprotkb:Q9P2L2|uniprotkb:Q9Y3T5|uniprotkb:E9PED3|intact:EBI-2555698|ensembl:ENSP00000265109.3|ensembl:ENSP00000388725.2|ensembl:ENSP00000422942.1	intact:EBI-2856663|uniprotkb:Q74U03|uniprotkb:A0A0H2W614|uniprotkb:Q7CIH3|uniprotkb:A0A384K9R3	psi-mi:rai14_human(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:RAI14(gene name)|psi-mi:RAI14(display_short)|uniprotkb:KIAA1334(gene name synonym)|uniprotkb:NORPEG(gene name synonym)	psi-mi:a0a5p8yf73_yerpe(display_long)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:YPO2157(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856660|imex:IM-13779-6136	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138992.1|refseq:NP_001138993.1|refseq:NP_001138994.1|refseq:NP_001138995.1|refseq:NP_001138997.1|refseq:NP_056392.2|refseq:XP_011512319.1|refseq:XP_011512320.1|refseq:XP_011512321.1|refseq:XP_011512322.1|refseq:XP_011512323.1|refseq:XP_011512324.1|refseq:XP_006714532.1|refseq:XP_016864824.1|ensembl:ENSG00000039560.14(gene)|ensembl:ENST00000265109.8(transcript)|ensembl:ENST00000428746.6(transcript)|ensembl:ENST00000503673.5(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030154""(cell differentiation)|go:""GO:0070161""(anchoring junction)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR042420|mint:Q9P0K7|panther:PTHR24129(orthology-group)"	"interpro:IPR020830|interpro:IPR020831|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0006006""(glucose metabolic process)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|interpro:IPR036291|refseq:YP_002347132.1|panther:PTHR10836(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:m5hQYx6HEi9QEAey1UiNpeAp6tw9606	rogid:WbFAcZfS8gDogRdS/wIZddO4pHg632	intact-crc:02705AC30F9247C9|rigid:Erz7D7VBSCGaU1OqL3UToymsx8g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A384KL32	uniprotkb:O60216	intact:EBI-2855180|uniprotkb:Q74WI8|uniprotkb:Q7CHC3|uniprotkb:Q0WHF1	intact:EBI-80739|uniprotkb:Q15001|uniprotkb:Q99568|ensembl:ENSP00000297338.2|ensembl:ENSP00000427923.2|ensembl:ENSP00000428158.2|ensembl:ENSP00000429342.2|ensembl:ENSP00000430273.2|ensembl:ENSP00000430524.2|ensembl:ENSP00000509687.1|uniprotkb:A8K0E0|intact:EBI-21354011	psi-mi:a0a384kl32_yerpe(display_long)|uniprotkb:YPO1258(locus name)	psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856672|imex:IM-13779-6132	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052947|interpro:IPR016583(Uncharacterised conserved protein UCP011452, HNH endonuclease domain, YhhZ)|interpro:IPR003615(HNH nuclease)|refseq:WP_002208839.1|interpro:IPR044925|panther:PTHR34319(orthology-group)	"ensembl:ENSG00000164754.16(gene)|ensembl:ENST00000297338.7(transcript)|ensembl:ENST00000517485.6(transcript)|ensembl:ENST00000517749.2(transcript)|ensembl:ENST00000519837.6(transcript)|ensembl:ENST00000520992.6(transcript)|ensembl:ENST00000522699.2(transcript)|ensembl:ENST00000687358.1(transcript)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000785""(chromatin)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000922""(spindle pole)|go:""GO:0001666""(response to hypoxia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005829""(cytosol)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0007131""(reciprocal meiotic recombination)|go:""GO:0008278""(cohesin complex)|go:""GO:0010972""(negative regulation of G2/M transition of mitotic cell cycle)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0030496""(midbody)|go:""GO:0030892""(mitotic cohesin complex)|go:""GO:0030893""(meiotic cohesin complex)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0034087""(establishment of mitotic sister chromatid cohesion)|go:""GO:0034089""(establishment of meiotic sister chromatid cohesion)|go:""GO:0034351""(negative regulation of glial cell apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045841""(negative regulation of mitotic metaphase/anaphase transition)|go:""GO:0045876""(positive regulation of sister chromatid cohesion)|go:""GO:0051301""(cell division)|go:""GO:0071168""(protein localization to chromatin)|go:""GO:0106222""(lncRNA binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140588""(chromatin looping)|go:""GO:1990414""(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|interpro:IPR049589|mint:O60216|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|rcsb pdb:6WGE|rcsb pdb:7W1M|rcsb pdb:7ZJS|rcsb pdb:8K4D|rcsb pdb:8P0A|rcsb pdb:8PQ5|rcsb pdb:8RO6|rcsb pdb:8RO7|rcsb pdb:8RO8|rcsb pdb:8RO9|rcsb pdb:8ROA|rcsb pdb:8ROB|rcsb pdb:8ROC|rcsb pdb:8ROD|rcsb pdb:8ROE|rcsb pdb:8ROF|rcsb pdb:8ROG|rcsb pdb:8ROH|rcsb pdb:8ROI|rcsb pdb:8ROJ|rcsb pdb:8ROK|rcsb pdb:8ROL|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|panther:PTHR12585(orthology-group)|efo:""Orphanet:199""|efo:""Orphanet:502""|dip:DIP-29201N|ensembl:ENSP00000297338.2|ensembl:ENSP00000427923.2|ensembl:ENSP00000430273.2|ensembl:ENSP00000430524.2|ensembl:ENSP00000429342.2|ensembl:ENSP00000428158.2|ensembl:ENSP00000509687.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:k8VGxxWPx+NdmGLFn262erw8Wf8632	rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606	intact-crc:5D53B99ED0D3EAC4|rigid:XPVBvnp/6Pn0ET5FI5rfDIIEamg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15153	uniprotkb:Q0WBF9	intact:EBI-489652|ensembl:ENSP00000249071.6|uniprotkb:Q9UDJ4	intact:EBI-2856682|uniprotkb:Q74X66|uniprotkb:Q8D1D1	psi-mi:rac2_human(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Small G protein(gene name synonym)|uniprotkb:GX(gene name synonym)|uniprotkb:RAC2(gene name)|psi-mi:RAC2(display_short)	psi-mi:pnp_yerpe(display_long)|uniprotkb:pnp(gene name)|psi-mi:pnp(display_short)|uniprotkb:Polynucleotide phosphorylase(gene name synonym)|uniprotkb:YPO3490(locus name)|uniprotkb:y0694(locus name)|uniprotkb:YP_0593(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856679|imex:IM-13779-6135	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000128340.16(gene)|ensembl:ENST00000249071.11(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006935""(chemotaxis)|go:""GO:0007015""(actin filament organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010810""(regulation of cell-substrate adhesion)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0043131""(erythrocyte enucleation)|go:""GO:0043304""(regulation of mast cell degranulation)|go:""GO:0045453""(bone resorption)|go:""GO:0045730""(respiratory burst)|go:""GO:0060263""(regulation of respiratory burst)|go:""GO:0060753""(regulation of mast cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070662""(mast cell proliferation)|go:""GO:0070668""(positive regulation of mast cell proliferation)|go:""GO:0071593""(lymphocyte aggregation)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:1902622""(regulation of neutrophil migration)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P15153|rcsb pdb:1DS6|rcsb pdb:2W2T|rcsb pdb:2W2V|rcsb pdb:2W2X|reactome:R-HSA-114604|reactome:R-HSA-1222556|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-4086400|reactome:R-HSA-5668599|reactome:R-HSA-6811558|reactome:R-HSA-9013404|refseq:NP_002863.1|efo:""Orphanet:183707""|dip:DIP-34291N|panther:PTHR24072(orthology-group)"	"refseq:WP_002209259.1|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR020568|interpro:IPR027408|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004654""(polyribonucleotide nucleotidyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0006401""(RNA catabolic process)|go:""GO:0006402""(mRNA catabolic process)|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612|refseq:YP_002348379.1|panther:PTHR11252(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:NYkPt/WNmKM3qAhhaufLCPkc/io9606	rogid:OtyeeLgdrKybDBd4sPZ7s/ufy78632	intact-crc:65988931142AFA7D|rigid:YZcTmm8TnKMGERNSRBxAX/NbEsc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15276	uniprotkb:Q0WKQ4	intact:EBI-447043|uniprotkb:O95369|uniprotkb:Q8IVX3|uniprotkb:B2RAG7|ensembl:ENSP00000445408.2	intact:EBI-2841918|uniprotkb:Q74YB1|uniprotkb:Q7CLB1|uniprotkb:A0A5P8YL50|uniprotkb:A0A0H2W0T4	psi-mi:rabe1_human(display_long)|uniprotkb:Rabaptin-5(gene name synonym)|uniprotkb:Rabaptin-5alpha(gene name synonym)|uniprotkb:Rabaptin-4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-17(gene name synonym)|uniprotkb:RABEP1(gene name)|psi-mi:RABEP1(display_short)|uniprotkb:RABPT5(gene name synonym)|uniprotkb:RABPT5A(gene name synonym)|uniprotkb:RAB5EP(gene name synonym)	psi-mi:q0wkq4_yerpe(display_long)|uniprotkb:spoT(gene name)|psi-mi:spoT(display_short)|uniprotkb:YPO0038(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856692|imex:IM-13779-6133	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001278510.1|refseq:NP_001077054.1|refseq:NP_004694.2|dip:DIP-29350N|rcsb pdb:1TU3|ensembl:ENSG00000029725.17(gene)|ensembl:ENST00000537505.6(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006915""(apoptotic process)|go:""GO:0008083""(growth factor activity)|go:""GO:0015031""(protein transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055037""(recycling endosome)|go:""GO:0061025""(membrane fusion)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1903441""(protein localization to ciliary membrane)|interpro:IPR003914(Rabaptin)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR018514|mint:Q15276|rcsb pdb:1P4U|rcsb pdb:1X79|rcsb pdb:4N3Y|rcsb pdb:4N3Z|rcsb pdb:4Q9U|reactome:R-HSA-8854214|panther:PTHR31179(orthology-group)"	"interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR007685(RelA/SpoT)|interpro:IPR004811(RelA/SpoT protein)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR033655|go:""GO:0015970""(guanosine tetraphosphate biosynthetic process)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002209002.1|interpro:IPR043519|refseq:YP_002345134.1|interpro:IPR045600|interpro:IPR045865"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:FDHgN8w6jbAPC3iQfeLY6sdLkrs9606	rogid:DFSylU3fdvQugjKDCGmQic4raK0632	intact-crc:13FB776384569731|rigid:SGczah9RPbN7dqTZKUyT8BtgQUk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14966	uniprotkb:A0A380PDF6	intact:EBI-372165|ensembl:ENSP00000235932.4|ensembl:ENSP00000356107.3|ensembl:ENSP00000402910.1|uniprotkb:B4E1K3|uniprotkb:C9JE77	intact:EBI-2856702|uniprotkb:Q74UZ3|uniprotkb:Q7CI04|uniprotkb:A0A0H2W3V4	psi-mi:rab7l_human(display_long)|uniprotkb:RAB29(gene name)|psi-mi:RAB29(display_short)|uniprotkb:RAB7L1(gene name synonym)|uniprotkb:Rab-7-like protein 1(gene name synonym)|uniprotkb:Ras-related protein Rab-29(gene name synonym)	psi-mi:a0a380pdf6_yerpe(display_long)|uniprotkb:yecS(gene name)|psi-mi:yecS(display_short)|uniprotkb:YPO1847(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856699|imex:IM-13779-6134	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000117280.13(gene)|ensembl:ENST00000235932.8(transcript)|ensembl:ENST00000367139.8(transcript)|ensembl:ENST00000414729.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005773""(vacuole)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007416""(synapse assembly)|go:""GO:0009617""(response to bacterium)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012505""(endomembrane system)|go:""GO:0019003""(GDP binding)|go:""GO:0019894""(kinesin binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032438""(melanosome organization)|go:""GO:0042110""(T cell activation)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042470""(melanosome)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070840""(dynein complex binding)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0097708""(intracellular vesicle)|go:""GO:1903441""(protein localization to ciliary membrane)|go:""GO:1905279""(regulation of retrograde transport, endosome to Golgi)|go:""GO:1990748""(cellular detoxification)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030697|mint:O14966|rcsb pdb:6HH2|rcsb pdb:8FO2|rcsb pdb:8FO8|rcsb pdb:8FO9|reactome:R-HSA-8873719|refseq:NP_001129134.1|refseq:NP_003920.1|refseq:NP_001129135.1|refseq:NP_001129136.1|refseq:XP_005245626.1|refseq:XP_005245627.1|refseq:XP_005245628.1|refseq:XP_006711668.1|refseq:XP_006711669.1|refseq:XP_016858237.1|refseq:XP_016858238.1|refseq:XP_016858239.1|dip:DIP-31215N|panther:PTHR24073(orthology-group)"	"interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_002211158.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015184""(L-cystine transmembrane transporter activity)|go:""GO:0015811""(L-cystine transport)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|interpro:IPR035906|interpro:IPR043429|refseq:YP_002346841.1|panther:PTHR30614(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iqqWBBmsxTZcMPjfgiBjdv8LzAw9606	rogid:pJ27jWvWt/SRd2N+cRvIV71qr60632	intact-crc:62E363D1EE7C9093|rigid:OKrQLAqQihUiRvZoY4kCPgpthso	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GVZ6	uniprotkb:Q96AX2	intact:EBI-2842971|uniprotkb:Q74W16|uniprotkb:A0A0H2W2X1|uniprotkb:Q7CJU6|uniprotkb:A0A3N4AZS9|uniprotkb:A0A384L7G7	intact:EBI-748121|uniprotkb:A8MXF5|uniprotkb:A8MYT0|uniprotkb:Q8IWA7|ensembl:ENSP00000376389.5|ensembl:ENSP00000436563.1|ensembl:ENSP00000483155.1	psi-mi:a0a2u2gvz6_yerpe(display_long)|uniprotkb:ubiF(gene name)|psi-mi:ubiF(display_short)|uniprotkb:YPO2621(locus name)	psi-mi:rab37_human(display_long)|uniprotkb:RAB37(gene name)|psi-mi:RAB37(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856732|imex:IM-13779-6140	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR010971(Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6)|go:""GO:0004497""(monooxygenase activity)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0016705""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:""GO:0071949""(FAD binding)|refseq:WP_002210347.1|interpro:IPR036188|refseq:YP_002347577.1|interpro:IPR051205"	"ensembl:ENSG00000172794.20(gene)|ensembl:ENST00000392613.10(transcript)|ensembl:ENST00000481224.5(transcript)|ensembl:ENST00000613645.1(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005768""(endosome)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-HSA-6798695|reactome:R-HSA-8873719|refseq:NP_001006639.1|refseq:NP_001157461.1|refseq:NP_001157462.1|refseq:NP_783865.1|refseq:NP_001317400.1|panther:PTHR47978(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zKOVHd4RmzcakJDi4rlK0Xy9yNc632	rogid:hXcRUHYbbCGiJhkLFTSrri04Uys9606	intact-crc:2223E69D0DE25F65|rigid:eZDQptjbCNHuGWEEjOA2ix06szE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20339	uniprotkb:O68779	intact:EBI-399437|uniprotkb:B4DJA5|intact:EBI-1048179|uniprotkb:Q6FI44|ensembl:ENSP00000273047.4	intact:EBI-2853455|intact:EBI-2855635|uniprotkb:Q74YF2|uniprotkb:Q7ARB0|uniprotkb:Q7BT13|uniprotkb:A0A3G5L6V4|uniprotkb:A0A1U8QYA4|uniprotkb:A0A0H2W5L4|uniprotkb:Q7CIE2	psi-mi:rab5a_human(display_long)|uniprotkb:RAB5A(gene name)|psi-mi:RAB5A(display_short)|uniprotkb:RAB5(gene name synonym)	psi-mi:o68779_yerpe(display_long)|uniprotkb:y1062(gene name)|psi-mi:y1062(display_short)|uniprotkb:ypmt1.80C(gene name synonym)|uniprotkb:ISU59_11670(orf name)|uniprotkb:ISU59_12615(orf name)|uniprotkb:YPMT1.80c(locus name)|uniprotkb:YPO0011(locus name)|uniprotkb:YPO1493(locus name)|uniprotkb:YPO1561(locus name)|uniprotkb:YPO1583(locus name)|uniprotkb:YPO1589(locus name)|uniprotkb:YPO1621(locus name)|uniprotkb:YPO1727(locus name)|uniprotkb:YPO1988(locus name)|uniprotkb:YPO2104(locus name)|uniprotkb:YPO2136(locus name)|uniprotkb:YPO2170(locus name)|uniprotkb:YPO2194(locus name)|uniprotkb:YPO2447(locus name)|uniprotkb:YPO2571(locus name)|uniprotkb:YPO2656(locus name)|uniprotkb:YPO2783(locus name)|uniprotkb:YPO2799(locus name)|uniprotkb:YPO2862(locus name)|uniprotkb:YPO2942(locus name)|uniprotkb:YPO3875(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856725|imex:IM-13779-6139	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004153.2|panther:PTHR24073(orthology-group)|refseq:NP_001278977.1|ensembl:ENSG00000144566.11(gene)|ensembl:ENST00000273047.9(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006909""(phagocytosis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0010008""(endosome membrane)|go:""GO:0012505""(endomembrane system)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0019003""(GDP binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032009""(early phagosome)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0036477""(somatodendritic compartment)|go:""GO:0042470""(melanosome)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043195""(terminal bouton)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043679""(axon terminus)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045121""(membrane raft)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0051036""(regulation of endosome size)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098559""(cytoplasmic side of early endosome membrane)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P20339|rcsb pdb:1N6H|rcsb pdb:1N6I|rcsb pdb:1N6K|rcsb pdb:1N6L|rcsb pdb:1N6N|rcsb pdb:1N6O|rcsb pdb:1N6P|rcsb pdb:1N6R|rcsb pdb:1R2Q|rcsb pdb:1TU3|rcsb pdb:1TU4|rcsb pdb:3MJH|rcsb pdb:4Q9U|rcsb pdb:7BL1|reactome:R-HSA-1660499|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9636383|reactome:R-HSA-9820960|reactome:R-HSA-983231|dip:DIP-380N"	"refseq:NP_395426.1|refseq:NP_857700.1|interpro:IPR001207(Transposase, mutator type)|refseq:YP_093966.1|refseq:WP_002209743.1|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|refseq:YP_002347531.1|refseq:YP_002345107.1|refseq:YP_002346509.1|refseq:YP_002346575.1|refseq:YP_002346595.1|refseq:YP_002346600.1|refseq:YP_002346632.1|refseq:YP_002346729.1|refseq:YP_002346973.1|refseq:YP_002347085.1|refseq:YP_002347114.1|refseq:YP_002347145.1|refseq:YP_002347167.1|refseq:YP_002347411.1|refseq:YP_002347607.1|refseq:YP_002347730.1|refseq:YP_002347741.1|refseq:YP_002347797.1|refseq:YP_002347869.1|refseq:YP_002348751.1|panther:PTHR33217(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:SgowwV7QSVCvfsqSDE+6CHmPmKA9606	rogid:y/++sl3PEsvjk5YqmX2+hc+8JHM632	intact-crc:B4C53FA394835D35|rigid:mnDpG1/HmshQTeHpqfZpRO4BcC0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H0N0	uniprotkb:P58543	intact:EBI-2856714|uniprotkb:Q53RU3|uniprotkb:Q6FIF7|uniprotkb:Q9P128|ensembl:ENSP00000387307.2|ensembl:ENSP00000517898.1	intact:EBI-2847390|uniprotkb:Q0WER7	psi-mi:rab6c_human(display_long)|uniprotkb:RAB6C(gene name)|psi-mi:RAB6C(display_short)|uniprotkb:WTH3(gene name synonym)|uniprotkb:Rab6-like protein WTH3(gene name synonym)	psi-mi:arab_yerpe(display_long)|uniprotkb:araB(gene name)|psi-mi:araB(display_short)|uniprotkb:YPO2254(locus name)|uniprotkb:y2095(locus name)|uniprotkb:YP_2050(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856711|imex:IM-13779-6137	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115520.2|ensembl:ENSG00000222014.6(gene)|ensembl:ENSG00000292140.1(gene)|ensembl:ENST00000410061.4(transcript)|ensembl:ENST00000709845.1(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0012505""(endomembrane system)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:1903292""(protein localization to Golgi membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:Q9H0N0|panther:PTHR24073(orthology-group)"	"interpro:IPR018485|interpro:IPR005929(L-ribulokinase)|interpro:IPR043129|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008741""(ribulokinase activity)|go:""GO:0019150""(D-ribulokinase activity)|go:""GO:0019321""(pentose metabolic process)|go:""GO:0019569""(L-arabinose catabolic process to xylulose 5-phosphate)|refseq:YP_002347221.1|panther:PTHR43435(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H7zc0o8L2ntXc4NsvKx8Zvm/6kw9606	rogid:hejpPk7Q+tUU+cmG5v4jTehB47I632	intact-crc:07A83E2141D35D3D|rigid:DKZ/5tGbvlCdfo1wSrWeUn4s3xU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W8Z8	uniprotkb:Q9BZG1	intact:EBI-2856746|uniprotkb:Q74QD6|uniprotkb:A0A3N4B8Z3|uniprotkb:Q7CGV9|uniprotkb:Q0WII5	intact:EBI-2856739|ensembl:ENSP00000301043.6|ensembl:ENSP00000378666.3|ensembl:ENSP00000404180.3|uniprotkb:Q8NCJ8|uniprotkb:Q96AR4|uniprotkb:Q5BJE6|uniprotkb:B4E3A0|uniprotkb:E9PEJ9	psi-mi:a0a0h2w8z8_yerpe(display_long)|uniprotkb:bgaB(gene name)|psi-mi:bgaB(display_short)|uniprotkb:pbg(gene name synonym)|uniprotkb:YPO0852(locus name)	psi-mi:rab34_human(display_long)|uniprotkb:RAB34(gene name)|psi-mi:RAB34(display_short)|uniprotkb:RAB39(gene name synonym)|uniprotkb:RAH(gene name synonym)|uniprotkb:Ras-related protein Rab-39(gene name synonym)|uniprotkb:Ras-related protein Rah(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856751|imex:IM-13779-6138	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029062|interpro:IPR013739(Beta-galactosidase C-terminal)|interpro:IPR013738(Beta-galactosidase trimerisation)|interpro:IPR003476(Glycoside hydrolase, family 42)|interpro:IPR013529(Glycoside hydrolase, family 42, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209897.1|go:""GO:0004565""(beta-galactosidase activity)|go:""GO:0006012""(galactose metabolic process)|go:""GO:0009341""(beta-galactosidase complex)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:YP_002345903.1"	"go:""GO:0060271""(cilium assembly)|go:""GO:0061824""(cytosolic ciliogenesis)|ensembl:ENSG00000109113.20(gene)|ensembl:ENST00000301043.10(transcript)|ensembl:ENST00000395245.9(transcript)|ensembl:ENST00000436730.7(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005795""(Golgi stack)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005929""(cilium)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031982""(vesicle)|go:""GO:0031985""(Golgi cisterna)|go:""GO:0032418""(lysosome localization)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045880""(positive regulation of smoothened signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090382""(phagosome maturation)|go:""GO:0090385""(phagosome-lysosome fusion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:Q9BZG1|reactome:R-HSA-8873719|refseq:NP_001138414.1|refseq:NP_114140.4|refseq:NP_001243206.1|refseq:NP_001243207.1|refseq:NP_001243205.1|panther:PTHR47977(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FQsKPHA93Zu/VST9+vZv6zeQ8DA632	rogid:iLgB/izd8tZSvcOniuaCsxkgl5I9606	intact-crc:8CF6F9BF82B98FB5|rigid:rt8DFF3YjGqo9JEFDfE2btmEE24	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6IQ26	uniprotkb:Q8ZJ73	intact:EBI-2856768|uniprotkb:Q9UPR1|uniprotkb:Q9H6U7|uniprotkb:Q9UFV0|uniprotkb:Q96GN3|uniprotkb:B4DJ15|uniprotkb:E9PS91|ensembl:ENSP00000328524.3	intact:EBI-2856761|uniprotkb:Q74XL3|uniprotkb:Q0WK57|uniprotkb:Q7CKS9	psi-mi:den5a_human(display_long)|uniprotkb:DENND5A(gene name)|psi-mi:DENND5A(display_short)|uniprotkb:KIAA1091(gene name synonym)|uniprotkb:RAB6IP1(gene name synonym)|uniprotkb:Rab6-interacting protein 1(gene name synonym)	psi-mi:actp_yerpe(display_long)|uniprotkb:actP(gene name)|psi-mi:actP(display_short)|uniprotkb:Acetate permease(gene name synonym)|uniprotkb:Acetate transporter ActP(gene name synonym)|uniprotkb:YPO0251(locus name)|uniprotkb:y0508(locus name)|uniprotkb:YP_0404(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856758|imex:IM-13779-6141	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001230183.1|refseq:NP_001335677.1|refseq:NP_056028.2|ensembl:ENSG00000184014.9(gene)|ensembl:ENST00000328194.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001194(DENN)|interpro:IPR004012(RUN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR036392|interpro:IPR037213|interpro:IPR037516|interpro:IPR043153|interpro:IPR047277|interpro:IPR047278|interpro:IPR047294|interpro:IPR047295|mint:Q6IQ26|reactome:R-HSA-8876198|panther:PTHR46070(orthology-group)"	"interpro:IPR014083(Cation/acetate symporter ActP)|interpro:IPR001734(Na+/solute symporter)|interpro:IPR018212|interpro:IPR050277|refseq:WP_002209029.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006814""(sodium ion transport)|go:""GO:0006847""(plasma membrane acetate transport)|go:""GO:0015123""(acetate transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|go:""GO:0043879""(glycolate transmembrane transporter activity)|interpro:IPR038377|refseq:YP_002345331.1|panther:PTHR48086(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:US2gf8uHwPzdyb0U2GcnEELsdPI9606	rogid:7/16s2sdy7eGyVVq+3+pmDS71Kc632	intact-crc:9A62988EB14CFEDC|rigid:IrgAYT7ry7riOzhsOrjRPlf+f7o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W867	uniprotkb:Q9H0R6	intact:EBI-2853738	intact:EBI-2856796|uniprotkb:Q5VWJ4|uniprotkb:Q9HA60|uniprotkb:Q9NV19|ensembl:ENSP00000358042.4	psi-mi:a0a0h2w867_yerpe(display_long)|uniprotkb:fliM(gene name)|psi-mi:fliM(display_short)|uniprotkb:fliM_2(gene name synonym)|uniprotkb:NCTC5923_04508(orf name)|uniprotkb:YP_3023(locus name)|uniprotkb:y3467(locus name)	psi-mi:gata_human(display_long)|uniprotkb:QRSL1(gene name)|psi-mi:QRSL1(display_short)|uniprotkb:Glutaminyl-tRNA synthase-like protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856793|imex:IM-13779-6142	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|interpro:IPR036429|uniprotkb:A0A6B3T5K9(uniprot-removed-ac)|refseq:WP_002211446.1"	"efo:""Orphanet:570491""|ensembl:ENSG00000130348.11(gene)|ensembl:ENST00000369046.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0030956""(""glutamyl-tRNA(Gln) amidotransferase complex"")|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032543""(mitochondrial translation)|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0070681""(glutaminyl-tRNAGln biosynthesis via transamidation)|interpro:IPR000120(Amidase signature enzyme)|interpro:IPR004412(""Glutamyl-tRNA(Gln) amidotransferase A subunit"")|interpro:IPR023631|interpro:IPR036928|mint:Q9H0R6|refseq:NP_060762.3|dip:DIP-48970N|panther:PTHR11895(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/17	rogid:oyGy7f/7t+MADi8Zs5mMlPzsGZk632	rogid:/RVDRYFvbHttKo9WEmryGNEBR+09606	intact-crc:27F1FFAE27E44A6F|rigid:CIHKT4ipKqhfcaWgeonlNQtJchk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0R8	uniprotkb:Q16769	intact:EBI-2842494	intact:EBI-2856807|uniprotkb:Q3KRG6|uniprotkb:Q16770|uniprotkb:Q53TR4|ensembl:ENSP00000344829.3	psi-mi:q8d0r8_yerpe(display_long)|uniprotkb:y1697(locus name)	psi-mi:qpct_human(display_long)|uniprotkb:QPCT(gene name)|psi-mi:QPCT(display_short)|uniprotkb:Glutaminyl cyclase(gene name synonym)|uniprotkb:Glutaminyl-tRNA cyclotransferase(gene name synonym)|uniprotkb:Glutamyl cyclase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856813|imex:IM-13779-6143	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010069(Adhesin HecA 20-residue repeat x2)|interpro:IPR006914(Protein of unknown function DUF638, haemagglutinin/haemolysin putative)|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR025157|interpro:IPR024973|go:""GO:0003824""(catalytic activity)|go:""GO:0090729""(toxin activity)"	"refseq:NP_036545.1|ensembl:ENSG00000115828.17(gene)|ensembl:ENST00000338415.8(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016603""(glutaminyl-peptide cyclotransferase activity)|go:""GO:0017186""(peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase)|go:""GO:0035580""(specific granule lumen)|go:""GO:0036211""(protein modification process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR007484(Peptidase M28)|interpro:IPR037457|interpro:IPR040234|mint:Q16769|rcsb pdb:2AFM|rcsb pdb:2AFO|rcsb pdb:2AFU|rcsb pdb:2AFS|rcsb pdb:2AFW|rcsb pdb:2AFX|rcsb pdb:2AFZ|rcsb pdb:2ZED|rcsb pdb:2ZEE|rcsb pdb:2ZEF|rcsb pdb:2ZEG|rcsb pdb:2ZEH|rcsb pdb:2ZEL|rcsb pdb:2ZEM|rcsb pdb:2ZEN|rcsb pdb:2ZEO|rcsb pdb:2ZEP|rcsb pdb:3PBB|rcsb pdb:3PBE|rcsb pdb:3SI0|rcsb pdb:4YU9|rcsb pdb:4YWY|rcsb pdb:6GBX|rcsb pdb:6YI1|rcsb pdb:6YJY|rcsb pdb:7CM0|rcsb pdb:7COZ|rcsb pdb:7CP0|rcsb pdb:7D8E|rcsb pdb:8HY3|rcsb pdb:8XGB|rcsb pdb:8XGT|rcsb pdb:8XGY|reactome:R-HSA-6798695|panther:PTHR12283(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9COFgNsEzFFJW9Occ82iuwwcF+Y632	rogid:P77dag9F4CgK4eLQHdFlYbz4Kxg9606	intact-crc:6FBEB4203EB4F9C0|rigid:Z/T3soirEFFL2FT0HfBYH0CJPpE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2K5	uniprotkb:Q8ZGW9	intact:EBI-948428|uniprotkb:Q2M1T9|uniprotkb:Q3ZCT5|uniprotkb:B7ZL65|ensembl:ENSP00000317903.6|ensembl:ENSP00000351784.2	intact:EBI-2856781|uniprotkb:Q0WHP5	psi-mi:r3hd2_human(display_long)|uniprotkb:R3HDM2(gene name)|psi-mi:R3HDM2(display_short)|uniprotkb:KIAA1002(gene name synonym)	psi-mi:biod1_yerpe(display_long)|uniprotkb:Dethiobiotin synthase 1(gene name synonym)|uniprotkb:bioD1(gene name)|psi-mi:bioD1(display_short)|uniprotkb:DTB synthetase 1(gene name synonym)|uniprotkb:YPO1154(locus name)|uniprotkb:y3028(locus name)|uniprotkb:YP_1006(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856786|imex:IM-13779-6144	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055740.3|refseq:NP_001317050.1|refseq:NP_001317051.1|refseq:NP_001317052.1|refseq:XP_016874520.1|refseq:XP_016874521.1|refseq:XP_016874522.1|ensembl:ENSG00000179912.21(gene)|ensembl:ENST00000347140.7(transcript)|ensembl:ENST00000358907.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR024771|interpro:IPR036867|interpro:IPR051937|rcsb pdb:1WHR|panther:PTHR15672(orthology-group)"	"interpro:IPR004472(Dethiobiotin synthase)|interpro:IPR027417|refseq:WP_002216554.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004141""(dethiobiotin synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009102""(biotin biosynthetic process)|refseq:YP_002346193.1|panther:PTHR43210(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EQSTKyI0NzNtSoHpnx7ac6T+GaU9606	rogid:qYf9r2/zbn9T1FkMmuqRTeKSAp8632	intact-crc:B83C6E6FA99A1B2E|rigid:nQRwgrIKmtipDEtRgQIzAD/uMKM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y4P0	uniprotkb:A0A380PL37	intact:EBI-2856823	intact:EBI-2848428|uniprotkb:Q74PX4|uniprotkb:A0A0H2W7W6|uniprotkb:Q7CG52|uniprotkb:A0A384KFS5	psi-mi:q9y4p0_human(display_long)|uniprotkb:DKFZp434C171(gene name)|psi-mi:DKFZp434C171(display_short)	psi-mi:a0a380pl37_yerpe(display_long)|uniprotkb:YPO0421(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856820|imex:IM-13779-6145	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR027463|refseq:WP_002209200.1|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:YP_002345497.1|panther:PTHR32063(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Mw7YesU/ws/lVDPFa8HTPgZe+2A9606	rogid:eNynpfVNIWDaaydEc5eAanQErH8632	intact-crc:AE8B47D00FF76363|rigid:wDSbQYGG97CmIrYmXLS+rHLwUPI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W225	uniprotkb:Q7Z7A1	intact:EBI-2844774	intact:EBI-2563266|uniprotkb:A2A2Y1|uniprotkb:B2RP67|uniprotkb:Q3MN79|uniprotkb:Q5FWF8|uniprotkb:Q5JVD0|uniprotkb:Q9Y489|uniprotkb:Q8TEP3|uniprotkb:Q6MZR3|uniprotkb:Q6PKC1|intact:EBI-2796138|ensembl:ENSP00000362962.1	psi-mi:a0a0h2w225_yerpe(display_long)|uniprotkb:sbcC2(gene name)|psi-mi:sbcC2(display_short)|uniprotkb:sbcC(gene name synonym)|uniprotkb:YP_0725(locus name)|uniprotkb:y0976(locus name)	psi-mi:cntrl_human(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym)|uniprotkb:Centrosomal protein 1(gene name synonym)|uniprotkb:CNTRL(gene name)|psi-mi:CNTRL(display_short)|uniprotkb:CEP110(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856831|imex:IM-13779-6150	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR027417|interpro:IPR038729|uniprotkb:A0A6B3T1W4(uniprot-removed-ac)|go:""GO:0004527""(exonuclease activity)|go:""GO:0006302""(double-strand break repair)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002223265.1"	"refseq:NP_008949.4|ensembl:ENSG00000119397.19(gene)|ensembl:ENST00000373855.7(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035904""(aorta development)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051301""(cell division)|go:""GO:0060976""(coronary vasculature development)|go:""GO:0090543""(Flemming body)|go:""GO:0090619""(meiotic spindle pole)|go:""GO:0097431""(mitotic spindle pole)|go:""GO:0120103""(centriolar subdistal appendage)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050836|mint:Q7Z7A1|reactome:R-HSA-1839117|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5655302|reactome:R-HSA-8854518|refseq:XP_005251736.1|refseq:NP_001317691.1|dip:DIP-47280N|panther:PTHR34491(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kLIIS2zCAycudIvZsl7pSdsTqz0632	rogid:wmPF3eCXN2WiNQIyd0CR3OGJROo9606	intact-crc:E0C485F5880F8A03|rigid:JwAbeI6bH7/22dKe6R/Zx5xcMgs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A1U8QSD0	uniprotkb:Q9UQC1	intact:EBI-2851086|uniprotkb:Q74YG8|uniprotkb:Q65AD8|uniprotkb:Q9ZGZ0	intact:EBI-354981	psi-mi:a0a1u8qsd0_yerpe(display_long)	psi-mi:q9uqc1_human(display_long)|uniprotkb:HSP70-1(gene name)|psi-mi:HSP70-1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856852|imex:IM-13779-6147	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094011.1|interpro:IPR025188|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR043129"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7V6Si5eR8IhffjxNCN0T7bRZj70632	rogid:5CycxNHAEy8lDjRntw5Gv8eHQGE9606	intact-crc:C4B9BC14AD5D7423|rigid:rSnGFEooecb26+CgIvoz8JUPEc0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0E1	uniprotkb:Q9UQM3	intact:EBI-2851171	intact:EBI-2801906	psi-mi:q8d0e1_yerpe(display_long)|uniprotkb:y2338(locus name)	psi-mi:q9uqm3_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856838|imex:IM-13779-6146	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR010252(Formiminoglutamate deiminase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR032466|go:""GO:0016810""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"")|interpro:IPR051607"	"interpro:IPR002452(Alpha tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005874""(microtubule)|go:""GO:0007017""(microtubule-based process)|go:""GO:0016787""(hydrolase activity)|go:""GO:0031514""(motile cilium)|interpro:IPR036525|interpro:IPR037103|interpro:IPR023123"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PERKzynzhTOYlkTaHwhsilRxm0U632	rogid:dXM+m/9m422DFgPGPKCLTsk17QQ9606	intact-crc:9CC1A5CCD8B30B43|rigid:kv93d/i5RaJCA1vP51Scet0/FOE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZED8	uniprotkb:Q9UQC1	intact:EBI-2840186|uniprotkb:Q0WET1	intact:EBI-354981	psi-mi:rnb_yerpe(display_long)|uniprotkb:rnb(gene name)|psi-mi:rnb(display_short)|uniprotkb:Exoribonuclease II(gene name synonym)|uniprotkb:YPO2235(locus name)|uniprotkb:y2077(locus name)|uniprotkb:YP_2034(locus name)	psi-mi:q9uqc1_human(display_long)|uniprotkb:HSP70-1(gene name)|psi-mi:HSP70-1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856845|imex:IM-13779-6149	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR022966|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011804(Ribonuclease II, bacterial)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008859""(exoribonuclease II activity)|refseq:WP_002210605.1|interpro:IPR001900(Ribonuclease II and R)|refseq:YP_002347207.1|interpro:IPR050180|panther:PTHR23355(orthology-group)"	"interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR043129"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8bPsungEsr2YreZsZg9IgHPm9uI632	rogid:5CycxNHAEy8lDjRntw5Gv8eHQGE9606	intact-crc:DC4D5336EEB49A98|rigid:SfTarYHvxqCk+h9qTu0aSH+dhVs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UQC1	uniprotkb:A0A2U2GUR4	intact:EBI-354981	intact:EBI-2856862|uniprotkb:Q0WCY9|uniprotkb:A0A380PF67|uniprotkb:Q7CJQ0|uniprotkb:A0A384LGX4	psi-mi:q9uqc1_human(display_long)|uniprotkb:HSP70-1(gene name)|psi-mi:HSP70-1(display_short)	psi-mi:a0a2u2gur4_yerpe(display_long)|uniprotkb:YPO2918(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856859|imex:IM-13779-6148	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR043129"	refseq:WP_002211559.1|refseq:YP_002347849.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5CycxNHAEy8lDjRntw5Gv8eHQGE9606	rogid:hCTr4oYTlUfoT7lERsa4W3VTgrc632	intact-crc:03DDCBEBDFB92804|rigid:mK1AkjN76f2clUmbh71vjp1yq44	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZD71	uniprotkb:Q9UQC1	intact:EBI-2856879|uniprotkb:Q0WDH2	intact:EBI-354981	psi-mi:era_yerpe(display_long)|uniprotkb:era(gene name)|psi-mi:era(display_short)|uniprotkb:YPO2719(locus name)|uniprotkb:y1298(locus name)|uniprotkb:YP_2523(locus name)	psi-mi:q9uqc1_human(display_long)|uniprotkb:HSP70-1(gene name)|psi-mi:HSP70-1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856876|imex:IM-13779-6153	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005662(GTP-binding protein Era)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030388|refseq:WP_002214829.1|go:""GO:0000028""(ribosomal small subunit assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0070181""(small ribosomal subunit rRNA binding)|refseq:YP_002347666.1|panther:PTHR42698(orthology-group)"	"interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR043129"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ckqm7XjL6CF11EM83zGqIPaGhw0632	rogid:5CycxNHAEy8lDjRntw5Gv8eHQGE9606	intact-crc:E4AF7583B8CAE9F7|rigid:Zm70qJkDsHNXMgfiLMaK9B0w0r8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YB08	uniprotkb:Q9UK73	intact:EBI-2856899|uniprotkb:Q74R69|uniprotkb:A0A0H2W858|uniprotkb:A0A2U2GYF6|uniprotkb:Q7CKY1|uniprotkb:A0A384KIP4	intact:EBI-310482|uniprotkb:O43146|ensembl:ENSP00000307298.4	psi-mi:a0a5p8yb08_yerpe(display_long)|uniprotkb:YPO3835(locus name)	psi-mi:fem1b_human(display_long)|uniprotkb:FEM1B(gene name)|psi-mi:FEM1B(display_short)|uniprotkb:KIAA0396(gene name synonym)|uniprotkb:F1AA(gene name synonym)|uniprotkb:FEM1-beta(gene name synonym)|uniprotkb:Fem-1-like death receptor-binding protein alpha(gene name synonym)|uniprotkb:Fem-1-like in apoptotic pathway protein alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856904|imex:IM-13779-6152	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029069|interpro:IPR003736(Phenylacetic acid degradation-related protein)|interpro:IPR006683(Thioesterase superfamily)|refseq:WP_002211482.1|go:""GO:0016289""(acyl-CoA hydrolase activity)|refseq:YP_002348713.1"	"refseq:NP_056137.1|ensembl:ENSG00000169018.6(gene)|ensembl:ENST00000306917.5(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0005123""(death receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051438""(regulation of ubiquitin-protein transferase activity)|go:""GO:0060442""(branching involved in prostate gland morphogenesis)|go:""GO:0060743""(epithelial cell maturation involved in prostate gland development)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000001""(regulation of DNA damage checkpoint)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:Q9UK73|rcsb pdb:6LBF|rcsb pdb:7CNG|rcsb pdb:7EL6|rcsb pdb:8IJ1|rcsb pdb:8JE1|rcsb pdb:8JE2|rcsb pdb:8WQA|rcsb pdb:8WQB|rcsb pdb:8WQC|rcsb pdb:8WQD|rcsb pdb:8WQE|rcsb pdb:8WQF|rcsb pdb:8WQG|rcsb pdb:8WQH|rcsb pdb:8WQI|reactome:R-HSA-8951664|dip:DIP-31663N|panther:PTHR24173(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:pSL513hhpuxfBcbx2la9eLhUem4632	rogid:ODOxw01NrJ8fUJv2XopsdTYtAr49606	intact-crc:9F683D17EC4D4A51|rigid:MqZQfDPD9D9UtEg1+qJpQNQVM70	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A7Y8RFP1	uniprotkb:Q9UQC1	intact:EBI-2854011|uniprotkb:Q74VT1|uniprotkb:Q0WH27|uniprotkb:A0A0H2W345|uniprotkb:Q7CHJ5|uniprotkb:A0A384L578	intact:EBI-354981	psi-mi:a0a7y8rfp1_yerpe(display_long)|uniprotkb:YPO1388(locus name)	psi-mi:q9uqc1_human(display_long)|uniprotkb:HSP70-1(gene name)|psi-mi:HSP70-1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856869|imex:IM-13779-6151	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005594(YadA-like, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|refseq:YP_002346411.1|interpro:IPR045584"	"interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR043129"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:p3FK6eF6RqucVMsp7QfWajIkzjw632	rogid:5CycxNHAEy8lDjRntw5Gv8eHQGE9606	intact-crc:925EE753A7B7D05A|rigid:kSFwD8n3jbtNE0CxkdqYoJH3Jlg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZS2	uniprotkb:Q9UPC7	intact:EBI-2845681	intact:EBI-2856891	psi-mi:q8czs2_yerpe(display_long)|uniprotkb:icc(gene name)|psi-mi:icc(display_short)|uniprotkb:y3513(locus name)|uniprotkb:cpdA(gene name synonym)	psi-mi:q9upc7_human(display_long)|uniprotkb:MPV17(gene name)|psi-mi:MPV17(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856888|imex:IM-13779-6154	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026575|interpro:IPR046379|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|go:""GO:0000166""(nucleotide binding)|go:""GO:0004115""(3',5'-cyclic-AMP phosphodiesterase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR050884"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pHtA80uk66ZaIBbjEM2kYqV0pog632	rogid:k/TY7wqAuVE1dqc+oZ+4qGAqtlc9606	intact-crc:A24C7C44C15F30F3|rigid:kPhIh8lUOm31vqq0fK+oxcxPfeM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GWQ4	uniprotkb:Q9UK73	intact:EBI-2845580|uniprotkb:Q74SR7|uniprotkb:Q0WDH9|uniprotkb:Q7CJQ8|uniprotkb:A0A380PMW3|uniprotkb:A0A384L966	intact:EBI-310482|uniprotkb:O43146|ensembl:ENSP00000307298.4	psi-mi:a0a2u2gwq4_yerpe(display_long)|uniprotkb:mclA(gene name)|psi-mi:mclA(display_short)|uniprotkb:Regulator of SigE(gene name synonym)|uniprotkb:Sigma-E anti-sigma factor RseA(gene name synonym)|uniprotkb:Sigma-E factor negative regulatory protein(gene name synonym)|uniprotkb:rseA(gene name synonym)|uniprotkb:YPO2712(locus name)	psi-mi:fem1b_human(display_long)|uniprotkb:FEM1B(gene name)|psi-mi:FEM1B(display_short)|uniprotkb:KIAA0396(gene name synonym)|uniprotkb:F1AA(gene name synonym)|uniprotkb:FEM1-beta(gene name synonym)|uniprotkb:Fem-1-like death receptor-binding protein alpha(gene name synonym)|uniprotkb:Fem-1-like in apoptotic pathway protein alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856918|imex:IM-13779-6158	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026279|interpro:IPR005573(Anti sigma-E protein RseA, C-terminal)|interpro:IPR005572(Anti sigma-E protein RseA, N-terminal)|go:""GO:0005886""(plasma membrane)|go:""GO:0016989""(sigma factor antagonist activity)|refseq:WP_002209673.1|interpro:IPR036147|refseq:YP_002347659.1|interpro:IPR052383"	"refseq:NP_056137.1|ensembl:ENSG00000169018.6(gene)|ensembl:ENST00000306917.5(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0005123""(death receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051438""(regulation of ubiquitin-protein transferase activity)|go:""GO:0060442""(branching involved in prostate gland morphogenesis)|go:""GO:0060743""(epithelial cell maturation involved in prostate gland development)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000001""(regulation of DNA damage checkpoint)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:Q9UK73|rcsb pdb:6LBF|rcsb pdb:7CNG|rcsb pdb:7EL6|rcsb pdb:8IJ1|rcsb pdb:8JE1|rcsb pdb:8JE2|rcsb pdb:8WQA|rcsb pdb:8WQB|rcsb pdb:8WQC|rcsb pdb:8WQD|rcsb pdb:8WQE|rcsb pdb:8WQF|rcsb pdb:8WQG|rcsb pdb:8WQH|rcsb pdb:8WQI|reactome:R-HSA-8951664|dip:DIP-31663N|panther:PTHR24173(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:LwZJGFoSTyhBT8PD/0j5gaZwEWc632	rogid:ODOxw01NrJ8fUJv2XopsdTYtAr49606	intact-crc:B52A19A81E8D994D|rigid:6EwHM2Z1/lDtbW/Mlqpf7pkXj8o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZEC9	uniprotkb:A6NHR9	intact:EBI-2846779|uniprotkb:Q0WES2	intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603.7	psi-mi:rnfb_yerpe(display_long)|uniprotkb:rnfB(gene name)|psi-mi:rnfB(display_short)|uniprotkb:Rnf electron transport complex subunit B(gene name synonym)|uniprotkb:YPO2245(locus name)|uniprotkb:YP_2043(locus name)|uniprotkb:y2086(locus name)	psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856944|imex:IM-13779-6159	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR010207(Electron transport complex, RnfB)|interpro:IPR016463(Electron transport complex, RnfB, subgroup)|interpro:IPR007202(Putative Fe-S cluster)|refseq:WP_002210596.1|interpro:IPR050294|go:""GO:0005886""(plasma membrane)|go:""GO:0009055""(electron transfer activity)|go:""GO:0022900""(electron transport chain)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:YP_002347216.1|panther:PTHR42859(orthology-group)"	"ensembl:ENSG00000101596.17(gene)|ensembl:ENST00000320876.11(transcript)|go:""GO:0001740""(Barr body)|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006302""(double-strand break repair)|go:""GO:0009048""(dosage compensation by inactivation of X chromosome)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043584""(nose development)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0051276""(chromosome organization)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|interpro:IPR055109|mint:A6NHR9|rcsb pdb:6MW7|refseq:NP_056110.2|efo:""Orphanet:2250""|efo:""Orphanet:269""|panther:PTHR22640(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8AghVg8h4AhMIHX7IMGRPKzPYis632	rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606	intact-crc:2BD833DC77BE00A6|rigid:k20BSTIr2cEfMTTwbRdmShl+TbA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZH09	uniprotkb:Q9UK73	intact:EBI-2856932|uniprotkb:Q0WHT9	intact:EBI-310482|uniprotkb:O43146|ensembl:ENSP00000307298.4	psi-mi:nadk_yerpe(display_long)|uniprotkb:nadK(gene name)|psi-mi:nadK(display_short)|uniprotkb:ATP-dependent NAD kinase(gene name synonym)|uniprotkb:YPO1106(locus name)|uniprotkb:YP_1050(locus name)|uniprotkb:y3074(locus name)	psi-mi:fem1b_human(display_long)|uniprotkb:FEM1B(gene name)|psi-mi:FEM1B(display_short)|uniprotkb:KIAA0396(gene name synonym)|uniprotkb:F1AA(gene name synonym)|uniprotkb:FEM1-beta(gene name synonym)|uniprotkb:Fem-1-like death receptor-binding protein alpha(gene name synonym)|uniprotkb:Fem-1-like in apoptotic pathway protein alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856937|imex:IM-13779-6157	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR002504(ATP-NAD/AcoX kinase)|refseq:WP_002210719.1|rcsb pdb:4HAO|go:""GO:0003951""(NAD+ kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006741""(NADP biosynthetic process)|go:""GO:0019674""(NAD metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051287""(NAD binding)|refseq:YP_002346149.1|panther:PTHR20275(orthology-group)"	"refseq:NP_056137.1|ensembl:ENSG00000169018.6(gene)|ensembl:ENST00000306917.5(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0005123""(death receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051438""(regulation of ubiquitin-protein transferase activity)|go:""GO:0060442""(branching involved in prostate gland morphogenesis)|go:""GO:0060743""(epithelial cell maturation involved in prostate gland development)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000001""(regulation of DNA damage checkpoint)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:Q9UK73|rcsb pdb:6LBF|rcsb pdb:7CNG|rcsb pdb:7EL6|rcsb pdb:8IJ1|rcsb pdb:8JE1|rcsb pdb:8JE2|rcsb pdb:8WQA|rcsb pdb:8WQB|rcsb pdb:8WQC|rcsb pdb:8WQD|rcsb pdb:8WQE|rcsb pdb:8WQF|rcsb pdb:8WQG|rcsb pdb:8WQH|rcsb pdb:8WQI|reactome:R-HSA-8951664|dip:DIP-31663N|panther:PTHR24173(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Vuq/Jluh23sZu6oyc5QVK4Wlomc632	rogid:ODOxw01NrJ8fUJv2XopsdTYtAr49606	intact-crc:1282D9ADC463C93F|rigid:8t1iJkLGH0CjrEJUUR9nHoEM1Rs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YB67	uniprotkb:Q9UK73	intact:EBI-2854189|uniprotkb:Q74R15|uniprotkb:Q0WAN8|uniprotkb:Q7CKU7|uniprotkb:A0A384K8J9	intact:EBI-310482|uniprotkb:O43146|ensembl:ENSP00000307298.4	psi-mi:a0a5p8yb67_yerpe(display_long)|uniprotkb:hemB(gene name)|psi-mi:hemB(display_short)|uniprotkb:ncf(gene name synonym)|uniprotkb:YPO3771(locus name)	psi-mi:fem1b_human(display_long)|uniprotkb:FEM1B(gene name)|psi-mi:FEM1B(display_short)|uniprotkb:KIAA0396(gene name synonym)|uniprotkb:F1AA(gene name synonym)|uniprotkb:FEM1-beta(gene name synonym)|uniprotkb:Fem-1-like death receptor-binding protein alpha(gene name synonym)|uniprotkb:Fem-1-like in apoptotic pathway protein alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856911|imex:IM-13779-6155	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR030656|interpro:IPR001731(Tetrapyrrole biosynthesis, porphobilinogen synthase)|interpro:IPR013785(Aldolase-type TIM barrel)|refseq:WP_002211541.1|go:""GO:0004655""(porphobilinogen synthase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0008270""(zinc ion binding)|refseq:YP_002348650.1|panther:PTHR11458(orthology-group)"	"refseq:NP_056137.1|ensembl:ENSG00000169018.6(gene)|ensembl:ENST00000306917.5(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0005123""(death receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051438""(regulation of ubiquitin-protein transferase activity)|go:""GO:0060442""(branching involved in prostate gland morphogenesis)|go:""GO:0060743""(epithelial cell maturation involved in prostate gland development)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000001""(regulation of DNA damage checkpoint)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:Q9UK73|rcsb pdb:6LBF|rcsb pdb:7CNG|rcsb pdb:7EL6|rcsb pdb:8IJ1|rcsb pdb:8JE1|rcsb pdb:8JE2|rcsb pdb:8WQA|rcsb pdb:8WQB|rcsb pdb:8WQC|rcsb pdb:8WQD|rcsb pdb:8WQE|rcsb pdb:8WQF|rcsb pdb:8WQG|rcsb pdb:8WQH|rcsb pdb:8WQI|reactome:R-HSA-8951664|dip:DIP-31663N|panther:PTHR24173(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:XQVKiDYNUJHbMuNEDPkNJYaXWVU632	rogid:ODOxw01NrJ8fUJv2XopsdTYtAr49606	intact-crc:72F06D767DBD2858|rigid:mJRjIoaYhwfGUYF3Oqd852HKfxg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WGT7	uniprotkb:Q9UK73	intact:EBI-2850542|uniprotkb:Q74VD6|uniprotkb:Q7CHP0|uniprotkb:A0A0H2W4Q1	intact:EBI-310482|uniprotkb:O43146|ensembl:ENSP00000307298.4	psi-mi:q0wgt7_yerpe(display_long)|uniprotkb:YPO1485(locus name)	psi-mi:fem1b_human(display_long)|uniprotkb:FEM1B(gene name)|psi-mi:FEM1B(display_short)|uniprotkb:KIAA0396(gene name synonym)|uniprotkb:F1AA(gene name synonym)|uniprotkb:FEM1-beta(gene name synonym)|uniprotkb:Fem-1-like death receptor-binding protein alpha(gene name synonym)|uniprotkb:Fem-1-like in apoptotic pathway protein alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856925|imex:IM-13779-6156	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010272(Type VI secretion system, VCA0110)|refseq:WP_002211940.1|refseq:YP_002346501.1|panther:PTHR35370(orthology-group)	"refseq:NP_056137.1|ensembl:ENSG00000169018.6(gene)|ensembl:ENST00000306917.5(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0005123""(death receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051438""(regulation of ubiquitin-protein transferase activity)|go:""GO:0060442""(branching involved in prostate gland morphogenesis)|go:""GO:0060743""(epithelial cell maturation involved in prostate gland development)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000001""(regulation of DNA damage checkpoint)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:Q9UK73|rcsb pdb:6LBF|rcsb pdb:7CNG|rcsb pdb:7EL6|rcsb pdb:8IJ1|rcsb pdb:8JE1|rcsb pdb:8JE2|rcsb pdb:8WQA|rcsb pdb:8WQB|rcsb pdb:8WQC|rcsb pdb:8WQD|rcsb pdb:8WQE|rcsb pdb:8WQF|rcsb pdb:8WQG|rcsb pdb:8WQH|rcsb pdb:8WQI|reactome:R-HSA-8951664|dip:DIP-31663N|panther:PTHR24173(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:alKNsFV/5ZWYoWO8CrdjCKkqbEU632	rogid:ODOxw01NrJ8fUJv2XopsdTYtAr49606	intact-crc:BB0CC37B4F587EB2|rigid:njeGJA0x1uBErrwdOfc6zTyL5so	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YAV7	uniprotkb:Q9UG01	intact:EBI-2839792|uniprotkb:Q74QU9|uniprotkb:Q0WA24|uniprotkb:Q7CG16|uniprotkb:A0A0H2W8V3	intact:EBI-2815009|uniprotkb:Q9UFJ9|uniprotkb:Q96HW4|uniprotkb:Q86X44|uniprotkb:Q9ULP1|uniprotkb:B2RNU5|uniprotkb:A5PKZ0|ensembl:ENSP00000260570.3|intact:EBI-28975847	psi-mi:a0a5p8yav7_yerpe(display_long)|uniprotkb:pelY(gene name)|psi-mi:pelY(display_short)|uniprotkb:YPO3994(locus name)	psi-mi:if172_human(display_long)|uniprotkb:IFT172(gene name)|psi-mi:IFT172(display_short)|uniprotkb:KIAA1179(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856958|imex:IM-13779-6160	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010702(Periplasmic pectate lyase)|refseq:YP_002348864.1|refseq:WP_002209555.1|go:""GO:0016837""(carbon-oxygen lyase activity, acting on polysaccharides)|go:""GO:0042597""(periplasmic space)|go:""GO:0045490""(pectin catabolic process)"	"ensembl:ENSG00000138002.16(gene)|ensembl:ENST00000260570.8(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0001947""(heart looping)|go:""GO:0005929""(cilium)|go:""GO:0005930""(axoneme)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007420""(brain development)|go:""GO:0008544""(epidermis development)|go:""GO:0009953""(dorsal/ventral pattern formation)|go:""GO:0010839""(negative regulation of keratinocyte proliferation)|go:""GO:0016485""(protein processing)|go:""GO:0021522""(spinal cord motor neuron differentiation)|go:""GO:0030992""(intraciliary transport particle B)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0035720""(intraciliary anterograde transport)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042073""(intraciliary transport)|go:""GO:0043616""(keratinocyte proliferation)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0045880""(positive regulation of smoothened signaling pathway)|go:""GO:0048596""(embryonic camera-type eye morphogenesis)|go:""GO:0060021""(roof of mouth development)|go:""GO:0060173""(limb development)|go:""GO:0060271""(cilium assembly)|go:""GO:0060348""(bone development)|go:""GO:0061525""(hindgut development)|go:""GO:0070986""(left/right axis specification)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097228""(sperm principal piece)|go:""GO:0097542""(ciliary tip)|go:""GO:0097598""(sperm cytoplasmic droplet)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036322|mint:Q9UG01|reactome:R-HSA-5610787|reactome:R-HSA-5620924|refseq:NP_056477.1|efo:""Orphanet:110""|efo:""Orphanet:140969""|efo:""Orphanet:474""|efo:""Orphanet:791""|panther:PTHR15722(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TdSmcoWgW+r5eNyU5ieC4Vae68s632	rogid:qPsplxtaPXhG90gLPi6qmmMIsy89606	intact-crc:8CCB5EAB0B7FC96C|rigid:svqE0xkB0YidOEn6egroiDrFeos	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A6NHR9	uniprotkb:Q7ARD3	intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603.7	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856951|imex:IM-13779-6161	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000101596.17(gene)|ensembl:ENST00000320876.11(transcript)|go:""GO:0001740""(Barr body)|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006302""(double-strand break repair)|go:""GO:0009048""(dosage compensation by inactivation of X chromosome)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043584""(nose development)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0051276""(chromosome organization)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|interpro:IPR055109|mint:A6NHR9|rcsb pdb:6MW7|refseq:NP_056110.2|efo:""Orphanet:2250""|efo:""Orphanet:269""|panther:PTHR22640(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:90209B2EAAE1973D|rigid:kc07zHJArVH6ugdyBNRffZQu+gU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UFZ8	uniprotkb:Q8CLV1	intact:EBI-2856978	intact:EBI-2856975	psi-mi:q9ufz8_human(display_long)|uniprotkb:DKFZp434I213(gene name)|psi-mi:DKFZp434I213(display_short)	psi-mi:q8clv1_yerpe(display_long)|uniprotkb:gabD_2(gene name)|psi-mi:gabD_2(display_short)|uniprotkb:NCTC5923_00696(orf name)|uniprotkb:y0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856972|imex:IM-13779-6162	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR050749|go:""GO:0004571""(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0009100""(glycoprotein metabolic process)|go:""GO:0016020""(membrane)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR050740|go:""GO:0036243""(""succinate-semialdehyde dehydrogenase (NADP+) activity"")|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Lf4DoGoJ+g3XU+OGdS2xMyHShtg9606	rogid:6zYk/wgwNbJp4HA15TbUfK5jmJs632	intact-crc:D53FFFB49B1B6707|rigid:IR3PlxhdUXzJRFHGK217sogVSBE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UF98	uniprotkb:Q8D176	intact:EBI-2815043	intact:EBI-2842041	psi-mi:q9uf98_human(display_long)|uniprotkb:DKFZp434E0321(gene name)|psi-mi:DKFZp434E0321(display_short)	psi-mi:q8d176_yerpe(display_long)|uniprotkb:y0939(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856986|imex:IM-13779-6163	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000782(Beta-Ig-H3/fasciclin)|interpro:IPR000538(Link)|interpro:IPR024731|go:""GO:0005509""(calcium ion binding)|go:""GO:0005540""(hyaluronic acid binding)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|interpro:IPR036378"	"interpro:IPR010158(Amidase, hydantoinase/carbamoylase)|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|go:""GO:0016813""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"")|go:""GO:0046872""(metal ion binding)|interpro:IPR036264"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Nzy6fyOUs+R9UkUSwIp+E/WU1Hs9606	rogid:/GOJxJQAHqgWtVu6otA2a4TvHfI632	intact-crc:E1E4C680C2AC07BF|rigid:yzJbnpGVhh+h7RK/I1pwZWGUcLI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UG01	uniprotkb:A0A5P8YLE8	intact:EBI-2815009|uniprotkb:Q9UFJ9|uniprotkb:Q96HW4|uniprotkb:Q86X44|uniprotkb:Q9ULP1|uniprotkb:B2RNU5|uniprotkb:A5PKZ0|ensembl:ENSP00000260570.3|intact:EBI-28975847	intact:EBI-2841627|uniprotkb:Q74Y48|uniprotkb:A0A384L7I3|uniprotkb:A0A0H2W0Y8|uniprotkb:Q7CFX4	psi-mi:if172_human(display_long)|uniprotkb:IFT172(gene name)|psi-mi:IFT172(display_short)|uniprotkb:KIAA1179(gene name synonym)	psi-mi:a0a5p8yle8_yerpe(display_long)|uniprotkb:malQ(gene name)|psi-mi:malQ(display_short)|uniprotkb:Amylomaltase(gene name synonym)|uniprotkb:Disproportionating enzyme(gene name synonym)|uniprotkb:YPO0126(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856965|imex:IM-13779-6164	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000138002.16(gene)|ensembl:ENST00000260570.8(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0001947""(heart looping)|go:""GO:0005929""(cilium)|go:""GO:0005930""(axoneme)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007420""(brain development)|go:""GO:0008544""(epidermis development)|go:""GO:0009953""(dorsal/ventral pattern formation)|go:""GO:0010839""(negative regulation of keratinocyte proliferation)|go:""GO:0016485""(protein processing)|go:""GO:0021522""(spinal cord motor neuron differentiation)|go:""GO:0030992""(intraciliary transport particle B)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0035720""(intraciliary anterograde transport)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042073""(intraciliary transport)|go:""GO:0043616""(keratinocyte proliferation)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0045880""(positive regulation of smoothened signaling pathway)|go:""GO:0048596""(embryonic camera-type eye morphogenesis)|go:""GO:0060021""(roof of mouth development)|go:""GO:0060173""(limb development)|go:""GO:0060271""(cilium assembly)|go:""GO:0060348""(bone development)|go:""GO:0061525""(hindgut development)|go:""GO:0070986""(left/right axis specification)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097228""(sperm principal piece)|go:""GO:0097542""(ciliary tip)|go:""GO:0097598""(sperm cytoplasmic droplet)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036322|mint:Q9UG01|reactome:R-HSA-5610787|reactome:R-HSA-5620924|refseq:NP_056477.1|efo:""Orphanet:110""|efo:""Orphanet:140969""|efo:""Orphanet:474""|efo:""Orphanet:791""|panther:PTHR15722(orthology-group)"	"interpro:IPR003385(Glycoside hydrolase, family 77)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR048458|go:""GO:0004134""(4-alpha-glucanotransferase activity)|go:""GO:0005975""(carbohydrate metabolic process)|refseq:YP_002345212.1|refseq:WP_002208925.1|panther:PTHR32438(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qPsplxtaPXhG90gLPi6qmmMIsy89606	rogid:JdI4fLE1gbtuqHycNtXRKKfEZ7Y632	intact-crc:F54F9EC70FE756F5|rigid:HHBIbS/9J/UTZ9tpQoK2VWOIJBw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UF61	uniprotkb:Q8D1B7	intact:EBI-2857005	intact:EBI-2840583|uniprotkb:Q74XW4	psi-mi:q9uf61_human(display_long)|uniprotkb:DKFZp434E202(gene name)|psi-mi:DKFZp434E202(display_short)	psi-mi:q8d1b7_yerpe(display_long)|uniprotkb:nadC(gene name)|psi-mi:nadC(display_short)|uniprotkb:Quinolinate phosphoribosyltransferase [decarboxylating](gene name synonym)|uniprotkb:YP_0260(locus name)|uniprotkb:y0762(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857009|imex:IM-13779-6165	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR027277|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004393(Nicotinate-nucleotide pyrophosphorylase)|interpro:IPR002638(Quinolinate phosphoribosyl transferase)|interpro:IPR022412|go:""GO:0004514""(""nicotinate-nucleotide diphosphorylase (carboxylating) activity"")|go:""GO:0009435""(NAD biosynthetic process)|interpro:IPR036068|interpro:IPR037128"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/U2/sSkZGyCrBbTqT9H97S6z3TA9606	rogid:TgisPBFeZCSKhBzO4ieWZ5gsm58632	intact-crc:B7D1E63B9CA47277|rigid:WkIhBCCBhzmSOiKd3xCs24cwsFU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UF61	uniprotkb:A0A2S9PFM0	intact:EBI-2857005	intact:EBI-2846871|uniprotkb:Q74QH1|uniprotkb:A0A0H2W7H4|uniprotkb:Q7CGR9|uniprotkb:A0A384LFS9	psi-mi:q9uf61_human(display_long)|uniprotkb:DKFZp434E202(gene name)|psi-mi:DKFZp434E202(display_short)	psi-mi:a0a2s9pfm0_yerpe(display_long)|uniprotkb:YPO0938(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857028|imex:IM-13779-6166	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR017755(N-carbamoylputrescine amidase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:WP_002209979.1|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0050126""(N-carbamoylputrescine amidase activity)|interpro:IPR036526|refseq:YP_002345985.1|interpro:IPR050345"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/U2/sSkZGyCrBbTqT9H97S6z3TA9606	rogid:VEt5ZICBEzJqD2dQaZCgWKgplSI632	intact-crc:CDC2435D60A90D8A|rigid:1IzQuimPHtz0WA1bNbFO2pYOnkE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UF61	uniprotkb:Q8D069	intact:EBI-2857005	intact:EBI-2857016|uniprotkb:Q74VC7	psi-mi:q9uf61_human(display_long)|uniprotkb:DKFZp434E202(gene name)|psi-mi:DKFZp434E202(display_short)	psi-mi:q8d069_yerpe(display_long)|uniprotkb:moeB(gene name)|psi-mi:moeB(display_short)|uniprotkb:YP_1384(locus name)|uniprotkb:y2674(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857021|imex:IM-13779-6168	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR012730(Molybdopterin synthase sulphurylase MoeB)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|go:""GO:0006777""(Mo-molybdopterin cofactor biosynthetic process)|go:""GO:0008641""(ubiquitin-like modifier activating enzyme activity)|interpro:IPR035985|interpro:IPR045886"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/U2/sSkZGyCrBbTqT9H97S6z3TA9606	rogid:cU1wfR2cW/jCKCcO3OQnpaYXdUk632	intact-crc:ABE91E8A118A0036|rigid:R6zDpH1k2fIHWVhka/y9qA2caNA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UF98	uniprotkb:A0A5P8YI89	intact:EBI-2815043	intact:EBI-2856996|uniprotkb:Q74W12|uniprotkb:Q0WDR7|uniprotkb:A0A0H2W1Y5|uniprotkb:Q7CJU9|uniprotkb:A0A384KHX2	psi-mi:q9uf98_human(display_long)|uniprotkb:DKFZp434E0321(gene name)|psi-mi:DKFZp434E0321(display_short)	psi-mi:a0a5p8yi89_yerpe(display_long)|uniprotkb:glnH(gene name)|psi-mi:glnH(display_short)|uniprotkb:YPO2615(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2856993|imex:IM-13779-6169	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000782(Beta-Ig-H3/fasciclin)|interpro:IPR000538(Link)|interpro:IPR024731|go:""GO:0005509""(calcium ion binding)|go:""GO:0005540""(hyaluronic acid binding)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|interpro:IPR036378"	interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR051455|refseq:WP_002210339.1|refseq:YP_002347571.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Nzy6fyOUs+R9UkUSwIp+E/WU1Hs9606	rogid:d/lT7X8seIFa6kLk/rLxIP1ZgME632	intact-crc:5EB888EF6304742E|rigid:ndneXbpI7V0tjGJZv7n1kU+bFK4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCV9	uniprotkb:Q9UF61	intact:EBI-2841552|uniprotkb:Q0WD51|uniprotkb:Q7CJL0|uniprotkb:Q74SA6	intact:EBI-2857005	psi-mi:mdtc_yerpe(display_long)|uniprotkb:mdtC(gene name)|psi-mi:mdtC(display_short)|uniprotkb:Multidrug transporter MdtC(gene name synonym)|uniprotkb:YPO2849(locus name)|uniprotkb:y1384(locus name)|uniprotkb:YP_2716(locus name)	psi-mi:q9uf61_human(display_long)|uniprotkb:DKFZp434E202(gene name)|psi-mi:DKFZp434E202(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857035|imex:IM-13779-6167	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR023931|interpro:IPR027463|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:WP_002209794.1|refseq:YP_002347787.1|panther:PTHR32063(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ingTP0+OfxdIVYajlP/RcmvKJUw632	rogid:/U2/sSkZGyCrBbTqT9H97S6z3TA9606	intact-crc:759DA0B5C522618E|rigid:Cfp9l2A1F0NFZb6j0h9E+cx/YiQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P1U1	uniprotkb:Q8CZU2	intact:EBI-1047175|uniprotkb:Q7Z526|uniprotkb:Q96BT2|uniprotkb:A8MTG1|uniprotkb:B4DFW4|ensembl:ENSP00000256001.8	intact:EBI-2843382	psi-mi:arp3b_human(display_long)|uniprotkb:ARP4(gene name synonym)|uniprotkb:Actin-like protein 3B(gene name synonym)|uniprotkb:ARP3-beta(gene name synonym)|uniprotkb:Actin-related protein ARP4(gene name synonym)|uniprotkb:ACTR3B(gene name)|psi-mi:ACTR3B(display_short)|uniprotkb:ARP11(gene name synonym)	psi-mi:q8czu2_yerpe(display_long)|uniprotkb:yapH(gene name)|psi-mi:yapH(display_short)|uniprotkb:y3396(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857082|imex:IM-13779-6171	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035225.1|refseq:NP_065178.1|ensembl:ENSG00000133627.18(gene)|ensembl:ENST00000256001.13(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0042995""(cell projection)|go:""GO:0070062""(extracellular exosome)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:Q9P1U1|panther:PTHR11937(orthology-group)"	"interpro:IPR024973|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0019867""(outer membrane)|interpro:IPR036709|interpro:IPR043990|interpro:IPR050909"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SKF1gLSYzo6jWlBcukVF0DBimA09606	rogid:w2l6qUtIv4INNGQ9HeM84bFptXU632	intact-crc:6A0D98978C2F64EE|rigid:fhsEemr+6Tw/JOfI7MNynkz2viA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P1Y0	uniprotkb:Q8D092	intact:EBI-2857074	intact:EBI-2845361	psi-mi:q9p1y0_human(display_long)|uniprotkb:HNMT(gene name)|psi-mi:HNMT(display_short)	psi-mi:q8d092_yerpe(display_long)|uniprotkb:fcuA(gene name)|psi-mi:fcuA(display_short)|uniprotkb:y2556(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857071|imex:IM-13779-6173	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029063|interpro:IPR016673(Histamine N-methyltransferase)|go:""GO:0032259""(methylation)|go:""GO:0046539""(histamine N-methyltransferase activity)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR010105(TonB-dependent siderophore receptor)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jfhnFnOdC1itna46YLP4vXnWXBc9606	rogid:7oNsiLRBKD+1PyrMueBNpf/zdLs632	intact-crc:4996408EF912A146|rigid:5tzhOPtj6ctxj0V4Gv4OvffJ9x4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKN6	uniprotkb:Q8N5J2	intact:EBI-2855015|uniprotkb:Q74S26	intact:EBI-372322|uniprotkb:Q9NUL9|uniprotkb:Q9P2F7|ensembl:ENSP00000354669.7|ensembl:ENSP00000354814.5|ensembl:ENSP00000507359.1|intact:EBI-2857053|uniprotkb:B3KWV8|uniprotkb:B3KWP4|uniprotkb:B4DXF2|uniprotkb:B4E1S4|uniprotkb:Q5SZF0|uniprotkb:D3DV09|uniprotkb:J3KP53	psi-mi:q8ckn6_yerpe(display_long)|uniprotkb:YP_2833(locus name)|uniprotkb:y3210(locus name)	psi-mi:miny1_human(display_long)|uniprotkb:MINDY1(gene name)|psi-mi:MINDY1(display_short)|uniprotkb:Deubiquitinating enzyme MINDY-1(gene name synonym)|uniprotkb:FAM63A(gene name synonym)|uniprotkb:KIAA1390(gene name synonym)|uniprotkb:Protein FAM63A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857064|imex:IM-13779-6172	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|go:""GO:0019867""(outer membrane)|interpro:IPR036709"	"ensembl:ENSG00000143409.18(gene)|ensembl:ENST00000361738.12(transcript)|ensembl:ENST00000361936.9(transcript)|ensembl:ENST00000683666.2(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006508""(proteolysis)|go:""GO:0016604""(nuclear body)|go:""GO:0016807""(cysteine-type carboxypeptidase activity)|go:""GO:0036435""(K48-linked polyubiquitin modification-dependent protein binding)|go:""GO:1990380""(K48-linked deubiquitinase activity)|interpro:IPR007518(Protein of unknown function DUF544)|interpro:IPR033979|rcsb pdb:5JKN|rcsb pdb:5JQS|rcsb pdb:5MN9|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6Y6R|rcsb pdb:6YJG|rcsb pdb:6Z90|refseq:NP_001035307.1|refseq:NP_001156730.1|refseq:NP_001156731.1|refseq:NP_001156732.1|refseq:NP_001306927.1|refseq:NP_060849.2|refseq:XP_016857261.1|refseq:XP_016857266.1|panther:PTHR18063(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1PmyGpcWP3bPwcEODrFtqgYq+a0632	rogid:igv+fceD9vJ66Q1RnoLANxnRFnI9606	intact-crc:60AA6B44ACE31AA3|rigid:LTbtx8XF4/uy3ZvJ1uArMoVt7Jo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YBQ9	uniprotkb:Q9TQE4	intact:EBI-2844830|uniprotkb:Q74X93|uniprotkb:A0A0H2W369|uniprotkb:Q7CKK6|uniprotkb:A0A2U2GXX7|uniprotkb:A0A384KXD1	intact:EBI-2857042	psi-mi:a0a5p8ybq9_yerpe(display_long)|uniprotkb:YPO3526(locus name)	psi-mi:q9tqe4_human(display_long)|uniprotkb:HLA-DQB1(gene name)|psi-mi:HLA-DQB1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857046|imex:IM-13779-6170	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR005170(Transporter-associated region)|interpro:IPR044751|go:""GO:0005886""(plasma membrane)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_002210164.1|interpro:IPR036318|refseq:YP_002348415.1|interpro:IPR046342"	"interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR050160|go:""GO:0006955""(immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0042613""(MHC class II protein complex)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JC3IVKKYgEftNqAeJWJ+daHPtRo632	rogid:U4QE5w+KHxYd27qypZR9INwVcK09606	intact-crc:4B496C3C2E30026D|rigid:qYptdfLzQOK/0d4d1VbRY8+WxMA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P0Q9	uniprotkb:A0A380PKK2	intact:EBI-2857112	intact:EBI-2847639|uniprotkb:Q74VA2|uniprotkb:A0A0H2W3M4|uniprotkb:Q7CHR2|uniprotkb:A0A384L7F9	psi-mi:q9p0q9_human(display_long)	psi-mi:a0a380pkk2_yerpe(display_long)|uniprotkb:YPO1523(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857119|imex:IM-13779-6176	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR034904|interpro:IPR000808(Mrp, conserved site)|interpro:IPR027417|refseq:WP_002211871.1|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0140663""(ATP-dependent FeS chaperone activity)|interpro:IPR033756|interpro:IPR019591|interpro:IPR044304|refseq:YP_002346539.1|panther:PTHR42961(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LdD8geee4wtf+QuVHsYvhHKDshs9606	rogid:llon2DY2OOAhmre4/3iLWmPJAH8632	intact-crc:448224553A476BA9|rigid:tB8veeareYXyIKFSWJytmTQ6nbY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P1U1	uniprotkb:Q8ZCW0	intact:EBI-1047175|uniprotkb:Q7Z526|uniprotkb:Q96BT2|uniprotkb:A8MTG1|uniprotkb:B4DFW4|ensembl:ENSP00000256001.8	intact:EBI-2842923|uniprotkb:Q7CJK9|uniprotkb:Q0WD52|uniprotkb:Q74SA7	psi-mi:arp3b_human(display_long)|uniprotkb:ARP4(gene name synonym)|uniprotkb:Actin-like protein 3B(gene name synonym)|uniprotkb:ARP3-beta(gene name synonym)|uniprotkb:Actin-related protein ARP4(gene name synonym)|uniprotkb:ACTR3B(gene name)|psi-mi:ACTR3B(display_short)|uniprotkb:ARP11(gene name synonym)	psi-mi:mdtb_yerpe(display_long)|uniprotkb:mdtB(gene name)|psi-mi:mdtB(display_short)|uniprotkb:Multidrug transporter MdtB(gene name synonym)|uniprotkb:YPO2848(locus name)|uniprotkb:y1385(locus name)|uniprotkb:YP_2715(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857089|imex:IM-13779-6174	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035225.1|refseq:NP_065178.1|ensembl:ENSG00000133627.18(gene)|ensembl:ENST00000256001.13(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0042995""(cell projection)|go:""GO:0070062""(extracellular exosome)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:Q9P1U1|panther:PTHR11937(orthology-group)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR022831|interpro:IPR027463|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:WP_002209793.1|refseq:YP_002347786.1|panther:PTHR32063(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SKF1gLSYzo6jWlBcukVF0DBimA09606	rogid:LHw1WKWrAW5/xlsQ5C6WVb5Ua3M632	intact-crc:AE55907E8C962491|rigid:Rov4rt9Aw206wILvqmBE2gIN80U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BEU0	uniprotkb:Q9P153	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	intact:EBI-2857096	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	psi-mi:q9p153_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857099|imex:IM-13779-6177	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	rogid:m/9y+SM7ASyfbbSNIjPRb1Z+7sc9606	intact-crc:35ABC1860F47EF13|rigid:AWHPL/8e95aMW4MPTssyt9VDp/w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P0M7	uniprotkb:Q8ZBP8	intact:EBI-2857126	intact:EBI-2857130|uniprotkb:Q0WBT6	psi-mi:q9p0m7_human(display_long)	"psi-mi:trud_yerpe(display_long)|uniprotkb:truD(gene name)|psi-mi:truD(display_short)|uniprotkb:tRNA pseudouridylate synthase D(gene name synonym)|uniprotkb:tRNA-uridine isomerase D(gene name synonym)|uniprotkb:YPO3359(locus name)|uniprotkb:y0830(locus name)|uniprotkb:YP_0328(locus name)|uniprotkb:""tRNA pseudouridine(13) synthase""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857135|imex:IM-13779-6178	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR042884	"interpro:IPR020103|interpro:IPR001656(tRNA pseudouridine synthase D)|interpro:IPR020119|interpro:IPR011760(tRNA pseudouridine synthase D, core)|interpro:IPR050170|refseq:WP_002209393.1|interpro:IPR042214|go:""GO:0001522""(pseudouridine synthesis)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0009982""(pseudouridine synthase activity)|go:""GO:0031119""(tRNA pseudouridine synthesis)|go:""GO:0160150""(""tRNA pseudouridine(13) synthase activity"")|interpro:IPR043165|refseq:YP_002348252.1|panther:PTHR47811(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KtSq9W36MavcvjRYSHXfFWPbRjc9606	rogid:C1bNcwOxG3QA4HfKBV4FoTPcRoc632	intact-crc:A0FBE8933E36F312|rigid:or+SMV5E8DOhe+TGkKcf3ytlZRg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P0Q9	uniprotkb:Q8D134	intact:EBI-2857112	intact:EBI-2857106	psi-mi:q9p0q9_human(display_long)	psi-mi:q8d134_yerpe(display_long)|uniprotkb:y1147(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857109|imex:IM-13779-6175	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR029035|interpro:IPR029061|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR030817|go:""GO:0000287""(magnesium ion binding)|go:""GO:0016823""(hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances)|go:""GO:0019310""(inositol catabolic process)|go:""GO:0019752""(carboxylic acid metabolic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|interpro:IPR045229"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LdD8geee4wtf+QuVHsYvhHKDshs9606	rogid:Z+Lv+S7FyW7TVAIuZrZ+Sn9Nlys632	intact-crc:1E14B0569B25331D|rigid:ezWN7k2q6nl5oLNLgUhB6JhTkHY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CL88	uniprotkb:Q9NXJ9	intact:EBI-2857164	intact:EBI-2810445	psi-mi:q8cl88_yerpe(display_long)|uniprotkb:y1834(locus name)	psi-mi:q9nxj9_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857168|imex:IM-13779-6179	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR051551|go:""GO:0019867""(outer membrane)|interpro:IPR036709|interpro:IPR043990"	"interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR052435|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR036600|interpro:IPR049257"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:G0mR8P5CZ016j1+vnvWb9h/RZDU632	rogid:eIwM1L2dR2qDXLwN2StvefxgHu49606	intact-crc:7B8552C6E1E25207|rigid:DEGwFbJlinxAIKOfJ4oTJcs+Qww	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NXJ9	uniprotkb:Q8ZAR2	intact:EBI-2810445	intact:EBI-2842016|uniprotkb:Q0WAS9	psi-mi:q9nxj9_human(display_long)	psi-mi:pur2_yerpe(display_long)|uniprotkb:purD(gene name)|psi-mi:purD(display_short)|uniprotkb:GARS(gene name synonym)|uniprotkb:Glycinamide ribonucleotide synthetase(gene name synonym)|uniprotkb:Phosphoribosylglycinamide synthetase(gene name synonym)|uniprotkb:YPO3729(locus name)|uniprotkb:y0501(locus name)|uniprotkb:YP_3092(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857182|imex:IM-13779-6182	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR052435|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR036600|interpro:IPR049257"	"interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|rcsb pdb:3MJF|go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_002210691.1|interpro:IPR037123|refseq:YP_002348609.1|panther:PTHR43472(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eIwM1L2dR2qDXLwN2StvefxgHu49606	rogid:lCNHTp0WZiZKDpeBBaNkuNmlzIc632	intact-crc:CC27177BB1C81B3B|rigid:vYwCM45DKX15lKvrzaROkRYyHlg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZN54	uniprotkb:Q8ZGK7	intact:EBI-2857145|uniprotkb:B4E0S9|uniprotkb:B4DK62|uniprotkb:B3KT65|uniprotkb:Q8N8N3|uniprotkb:B7Z3H6|uniprotkb:Q9NXL0|uniprotkb:H3BUG7|ensembl:ENSP00000268676.7	intact:EBI-2857155|uniprotkb:Q8D024|uniprotkb:Q0WHC8	psi-mi:defi8_human(display_long)|uniprotkb:DEF8(gene name)|psi-mi:DEF8(display_short)	psi-mi:efpl_yerpe(display_long)|uniprotkb:YPO1284(locus name)|uniprotkb:y2901(locus name)|uniprotkb:YP_1307(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857142|imex:IM-13779-6181	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229745.1|refseq:NP_001229746.1|refseq:NP_001229747.1|refseq:NP_001229748.1|refseq:NP_001229749.1|refseq:NP_001229750.1|refseq:NP_001229751.1|refseq:NP_060172.1|refseq:NP_997397.1|refseq:XP_016878847.1|refseq:XP_016878849.1|refseq:XP_016878852.1|refseq:XP_016878856.1|refseq:XP_016878857.1|refseq:XP_016878858.1|refseq:XP_005256375.2|ensembl:ENSG00000140995.17(gene)|ensembl:ENST00000268676.11(transcript)|go:""GO:0032418""(lysosome localization)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:1900029""(positive regulation of ruffle assembly)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR025258|interpro:IPR046349|interpro:IPR047983|interpro:IPR051366|mint:Q6ZN54|panther:PTHR12326(orthology-group)"	"interpro:IPR015365(Elongation factor P, C-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR020599|interpro:IPR013185(Translation elongation factor, KOW-like)|interpro:IPR011897(Translation elongation factor P-like protein YeiP)|interpro:IPR001059(Translation elongation factor P/YeiP, central)|interpro:IPR013852(Translation elongation factor P/YeiP, conserved site)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|refseq:WP_002228019.1|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0043043""(peptide biosynthetic process)|refseq:YP_002346310.1|panther:PTHR30053(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AehFw7CwQB+Nn1dUNK7z6J4b4Ks9606	rogid:DIHAOB8S4lcaSC350HLia+oYNCA632	intact-crc:07B90FBAC1805171|rigid:ljt2d/KLeC6J1qSaB3SgazMzySs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YCX0	uniprotkb:Q9NXJ9	intact:EBI-2847136|uniprotkb:Q0WIK5|uniprotkb:Q7CGX5|uniprotkb:A0A384LKL7	intact:EBI-2810445	psi-mi:a0a5p8ycx0_yerpe(display_long)|uniprotkb:agaZ(gene name)|psi-mi:agaZ(display_short)|uniprotkb:YPO0832(locus name)	psi-mi:q9nxj9_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857175|imex:IM-13779-6180	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR012062(D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit AgaZ)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0009024""(tagatose-6-phosphate kinase activity)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:2001059""(D-tagatose 6-phosphate catabolic process)|refseq:WP_002209876.1|refseq:YP_002345883.1|interpro:IPR050303|panther:PTHR32502(orthology-group)"	"interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR052435|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR036600|interpro:IPR049257"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jeuVSNHzZuV4uI3LfyWid3P6eWE632	rogid:eIwM1L2dR2qDXLwN2StvefxgHu49606	intact-crc:26BC4456AFE5FBF3|rigid:ZsrA4kMY1owLS1mSNU1b/s8sJpI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NXJ9	uniprotkb:Q8ZG09	intact:EBI-2810445	intact:EBI-2842762|uniprotkb:Q74VB1|uniprotkb:Q7CHQ5|uniprotkb:Q0WGR1	psi-mi:q9nxj9_human(display_long)	psi-mi:mao1_yerpe(display_long)|uniprotkb:maeA(gene name)|psi-mi:maeA(display_short)|uniprotkb:YPO1511(locus name)|uniprotkb:y2658(locus name)|uniprotkb:YP_1401(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857189|imex:IM-13779-6187	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR052435|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR036600|interpro:IPR049257"	"interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR001891(Malic oxidoreductase)|interpro:IPR023667|go:""GO:0004470""(malic enzyme activity)|go:""GO:0004471""(""malate dehydrogenase (decarboxylating) (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006108""(malate metabolic process)|go:""GO:0008948""(oxaloacetate decarboxylase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051287""(NAD binding)|refseq:WP_002211968.1|interpro:IPR036291|interpro:IPR037062|refseq:YP_002346527.1|interpro:IPR046346|panther:PTHR23406(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eIwM1L2dR2qDXLwN2StvefxgHu49606	rogid:3qTE5pPHB/ePJ+WGe7JGTqu1xJA632	intact-crc:3515A652814D3896|rigid:4th6T4DMSk0HNJuX1JlHCID0Ieo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NWB7	uniprotkb:A0A0H2W3V7	intact:EBI-725672|intact:EBI-1581177|uniprotkb:Q96DA9|ensembl:ENSP00000264538.3	intact:EBI-2839946|uniprotkb:A0A384LA47|uniprotkb:Q74UY8|uniprotkb:Q0WFV3|uniprotkb:Q7CHZ9|uniprotkb:A0A5P8YEB4	psi-mi:ift57_human(display_long)|uniprotkb:IFT57(gene name)|psi-mi:IFT57(display_short)|uniprotkb:DERP8(gene name synonym)|uniprotkb:ESRRBL1(gene name synonym)|uniprotkb:HIPPI(gene name synonym)|uniprotkb:HIP1-interacting protein(gene name synonym)|uniprotkb:Estrogen-related receptor beta-like protein 1(gene name synonym)|uniprotkb:Dermal papilla-derived protein 8(gene name synonym)|uniprotkb:MHS4R2(gene name synonym)	psi-mi:a0a0h2w3v7_yerpe(display_long)|uniprotkb:flaV(gene name)|psi-mi:flaV(display_short)|uniprotkb:Flagellar cap protein(gene name synonym)|uniprotkb:flbC(gene name synonym)|uniprotkb:fliD(gene name synonym)|uniprotkb:YPO1841(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857207|imex:IM-13779-6186	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:508501""|ensembl:ENSG00000114446.5(gene)|ensembl:ENST00000264538.4(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0001947""(heart looping)|go:""GO:0003677""(DNA binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005929""(cilium)|go:""GO:0005930""(axoneme)|go:""GO:0006915""(apoptotic process)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0010839""(negative regulation of keratinocyte proliferation)|go:""GO:0030992""(intraciliary transport particle B)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0035720""(intraciliary anterograde transport)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042073""(intraciliary transport)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043616""(keratinocyte proliferation)|go:""GO:0044292""(dendrite terminus)|go:""GO:0044458""(motile cilium assembly)|go:""GO:0060271""(cilium assembly)|go:""GO:0097542""(ciliary tip)|go:""GO:0097546""(ciliary base)|go:""GO:1905515""(non-motile cilium assembly)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR019530|mint:Q9NWB7|reactome:R-HSA-5610787|reactome:R-HSA-5620924|refseq:NP_060480.1|panther:PTHR16011(orthology-group)"	"refseq:YP_002346835.1|interpro:IPR010809(Flagellar hook-associated 2, C-terminal)|interpro:IPR003481(Flagellar hook-associated protein 2, N-terminal)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0009421""(bacterial-type flagellum filament cap)|go:""GO:0009424""(bacterial-type flagellum hook)|refseq:WP_002211150.1|interpro:IPR040026"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dwediEVcY3c1oEqj6xTpaae4aTk9606	rogid:y6JIeGlhmIELicCmvORRUOwywBM632	intact-crc:BE2868E47B3A9EF1|rigid:orm3owxkXcWxq9ulLW6ukkBN5r4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NTU6	uniprotkb:A0A380PKG2	intact:EBI-2842454	intact:EBI-2857235|uniprotkb:Q74V84|uniprotkb:A0A5P8YGK0|uniprotkb:Q7CHS5|uniprotkb:A0A0H2W4J4	psi-mi:q9ntu6_human(display_long)|uniprotkb:DKFZp434P211(gene name)|psi-mi:DKFZp434P211(display_short)	psi-mi:a0a380pkg2_yerpe(display_long)|uniprotkb:yeeF(gene name)|psi-mi:yeeF(display_short)|uniprotkb:YPO1557(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857240|imex:IM-13779-6185	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR043220	"interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR050367|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_002211902.1|refseq:YP_002346571.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cgvTN7kcRrPpxQFNdD0pwOs1yWc9606	rogid:5F169y+0XPPzeklWGv4DyAI+Hlc632	intact-crc:167ACB2BF37709B9|rigid:lcDdXRfCYCnO2l6GiGDp9mVry9I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2857196	uniprotkb:A0A0H2W8E2	-	intact:EBI-2845898|uniprotkb:Q74Q33|uniprotkb:Q0WJG5|uniprotkb:Q7CG91|uniprotkb:A0A2U2H085|uniprotkb:A0A384KB95	psi-mi:l37a4_human(display_short)|psi-mi:EBI-2857196(display_long)|uniprotkb:LRRC37A4(gene name)|psi-mi:LRRC37A4(display_short)	psi-mi:a0a0h2w8e2_yerpe(display_long)|uniprotkb:YPO0500(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857200|imex:IM-13779-6183	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q9NWC8(uniprot-removed-ac)	interpro:IPR008312(Uncharacterised conserved protein UCP028301)|refseq:WP_002210481.1|refseq:YP_002345573.1	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ekV9BYJ9EhjIJ9od8ulrilFQoIY9606	rogid:r1UlnEbb/K20reicDTxy4VHlP90632	intact-crc:FF6E52B4E98F49CF|rigid:sAA47skPv80EBJmtC4x68uuyWX8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CK83	uniprotkb:Q86WJ1	intact:EBI-2851851|uniprotkb:Q74QS6	intact:EBI-2340020|intact:EBI-2857214|uniprotkb:Q96HF7|uniprotkb:Q9BVJ1|uniprotkb:Q6DD94|uniprotkb:Q53EZ3|uniprotkb:Q9NVV8|uniprotkb:Q86XH3|uniprotkb:Q5VXX7|uniprotkb:A5YM64|uniprotkb:Q6PK83|uniprotkb:Q96SP3|uniprotkb:B4DDE1|uniprotkb:B5MDZ7|ensembl:ENSP00000358262.4	psi-mi:q8ck83_yerpe(display_long)|uniprotkb:accC1(gene name)|psi-mi:accC1(display_short)|uniprotkb:YP_3384(locus name)|uniprotkb:y4042(locus name)	psi-mi:chd1l_human(display_long)|uniprotkb:CHD1L(gene name)|psi-mi:CHD1L(display_short)|uniprotkb:ALC1(gene name synonym)|uniprotkb:Amplified in liver cancer protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857228|imex:IM-13779-6184	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|go:""GO:0005524""(ATP binding)|go:""GO:0016874""(ligase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR052032"	"dip:DIP-48933N|ensembl:ENSG00000131778.20(gene)|ensembl:ENST00000369258.8(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006974""(DNA damage response)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031491""(nucleosome binding)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0090734""(site of DNA damage)|go:""GO:0140566""(histone reader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140658""(ATP-dependent chromatin remodeler activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:0160004""(poly-ADP-D-ribose modification-dependent protein binding)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031053|interpro:IPR038718|interpro:IPR043472|interpro:IPR049730|mint:Q86WJ1|rcsb pdb:6ZHX|rcsb pdb:6ZHY|rcsb pdb:7ENN|rcsb pdb:7EPU|rcsb pdb:7OTQ|rcsb pdb:8B0A|reactome:R-HSA-5696395|reactome:R-HSA-5696400|refseq:NP_001243266.1|refseq:NP_001243267.1|refseq:NP_001335382.1|refseq:NP_001335385.1|refseq:NP_001335386.1|refseq:NP_001335387.1|refseq:NP_001335388.1|refseq:NP_001335389.1|refseq:NP_001335390.1|refseq:NP_001335391.1|refseq:NP_001335392.1|refseq:NP_001335393.1|refseq:NP_001335394.1|refseq:NP_001335395.1|refseq:NP_004275.4|refseq:NP_078844.2|ensembl:ENSP00000358262.4|ensembl:ENST00000369259.4|ensembl:ENSP00000358263.3|panther:PTHR47157(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zWNetqBcgNgoffpGm1WuBpGKZiA632	rogid:e8j47togv1uhkm+TwhWyG6OxiiE9606	intact-crc:02E1F00E72F458B8|rigid:bef2OEZvt2DbdewYNSaeWsJf7Rk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCA8	uniprotkb:A0A2S9PLH1	intact:EBI-2815064	intact:EBI-2856592|uniprotkb:Q74X46|uniprotkb:Q7CKH1|uniprotkb:A0A0H2W2R5	psi-mi:q9hca8_human(display_long)|uniprotkb:ZNF224(gene name)|psi-mi:ZNF224(display_short)	psi-mi:a0a2s9plh1_yerpe(display_long)|uniprotkb:YPO3468(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857266|imex:IM-13779-6190	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001909(Krueppel-associated  box)|interpro:IPR050169|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR036051"	"refseq:WP_002209281.1|interpro:IPR008397(Alginate lyase)|interpro:IPR008929(Chondroitin AC/alginate lyase)|go:""GO:0016829""(lyase activity)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348357.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eRV2QNgkdyBy3vqhca1NFv3k9qU9606	rogid:XJauDb6vvXdcLKHXeXt+Js2URk8632	intact-crc:60F2251AE51E0EA7|rigid:MkXSyRkGTChHl2NeAEJrPsK1ZD8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZM8	uniprotkb:Q9NPH2	intact:EBI-2848309	intact:EBI-720563|intact:EBI-1050340|uniprotkb:Q7Z525|uniprotkb:Q9BT65|uniprotkb:Q9H2Y2|uniprotkb:Q9NSU0|uniprotkb:Q9NVW7|uniprotkb:Q6NXT5|uniprotkb:B3KRT1|uniprotkb:G5E9U0|ensembl:ENSP00000337746.7	psi-mi:q8czm8_yerpe(display_long)|uniprotkb:ptsA(gene name)|psi-mi:ptsA(display_short)|uniprotkb:y3776(locus name)	psi-mi:ino1_human(display_long)|uniprotkb:INO1(gene name synonym)|uniprotkb:ISYNA1(gene name)|psi-mi:ISYNA1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase A1(gene name synonym)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857247|imex:IM-13779-6191	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR018274|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR023151|interpro:IPR006318(Phosphoenolpyruvate-protein phosphotransferase)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR008731(Phosphotransferase system, PEP-utilising enzyme, N-terminal)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|go:""GO:0005737""(cytoplasm)|go:""GO:0008965""(phosphoenolpyruvate-protein phosphotransferase activity)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR040442|interpro:IPR035895|interpro:IPR036618|interpro:IPR036637|interpro:IPR050499"	"refseq:NP_001164409.1|refseq:NP_057452.1|refseq:NP_001240318.1|ensembl:ENSG00000105655.19(gene)|ensembl:ENST00000338128.13(transcript)|go:""GO:0004512""(inositol-3-phosphate synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006021""(inositol biosynthetic process)|go:""GO:0008654""(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|mint:Q9NPH2|reactome:R-HSA-1855183|panther:PTHR11510(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yFrXLYA0rYHKZA16/O8hjY0IDfU632	rogid:46Ryo/iaI6hmbkuetMsJSyrm3FU9606	intact-crc:47C6AC1339BE6BBD|rigid:CuHfvKGPNFUcXXJOj5r1lA5sLnA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZV1	uniprotkb:Q9HCK3	intact:EBI-2843995	intact:EBI-2857254	psi-mi:q8czv1_yerpe(display_long)|uniprotkb:y3335(locus name)	psi-mi:q9hck3_human(display_long)|uniprotkb:KIAA1569(gene name)|psi-mi:KIAA1569(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857259|imex:IM-13779-6189	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR021307	"interpro:IPR054085|interpro:IPR054086|interpro:IPR054087|interpro:IPR054088|interpro:IPR054089|interpro:IPR054090|interpro:IPR054091|interpro:IPR054092|refseq:NP_115518.3|interpro:IPR013783(Immunoglobulin-like fold)|go:""GO:0051298""(centrosome duplication)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0090222""(centrosome-templated microtubule nucleation)|interpro:IPR039103"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mvlSMRwfbr0qayRobyN7vmxNk50632	rogid:RJZJz1MK/F5jkCdG/gcqBSikbTA9606	intact-crc:47AB310B079E2F66|rigid:u1Z+FuHUVDQA1ACpociXFyeE8es	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HB72	uniprotkb:Q7ARD3	intact:EBI-2857276	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:q9hb72_human(display_long)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857273|imex:IM-13779-6188	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007513(Four F5 protein)|interpro:IPR026939|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR045230"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xOoYNJ+HwNiyrBhWa7qFimZBcQ49606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:95A36335BB2118B6|rigid:G3j4fX77zKlnZwgPOdn9N+8Ee/A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKW7	uniprotkb:A5PLN9	intact:EBI-2845318	intact:EBI-2857298|uniprotkb:Q49A23|uniprotkb:Q4JHG0|uniprotkb:Q17RZ9|uniprotkb:Q6MZG4|uniprotkb:Q8TCM2|uniprotkb:Q9H8I3|ensembl:ENSP00000382367.3	psi-mi:q8ckw7_yerpe(display_long)|uniprotkb:y2698(locus name)	psi-mi:tpc13_human(display_long)|uniprotkb:TRAPPC13(gene name)|psi-mi:TRAPPC13(display_short)|uniprotkb:C5orf44(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857295|imex:IM-13779-6192	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002231240.1|interpro:IPR028244|interpro:IPR018769|interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)	"refseq:NP_001087224.1|refseq:NP_001087225.1|refseq:NP_079217.2|refseq:NP_001230666.1|ensembl:ENSG00000113597.19(gene)|ensembl:ENST00000399438.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006901""(vesicle coating)|go:""GO:0099022""(vesicle tethering)|go:""GO:1990071""(TRAPPII protein complex)|go:""GO:1990072""(TRAPPIII protein complex)|interpro:IPR010378(Protein of unknown function DUF974)|mint:A5PLN9|reactome:R-HSA-8876198|dip:DIP-48284N|panther:PTHR13134(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Nrvz9YxMF2TgzN5e3ZNazVacK34632	rogid:av9WiddXfzAIr65RDo2AXQfWtVk9606	intact-crc:3B8D9DC86AB2A98E|rigid:7bdqkMyfJSt56BIu6+MA6gbXnBE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H346	uniprotkb:Q96DY7	intact:EBI-2849136|uniprotkb:Q74TG8|uniprotkb:A0A0H2W5H4|uniprotkb:Q0WEC0|uniprotkb:Q7CIT1|uniprotkb:A0A384KWM5	intact:EBI-2857286|uniprotkb:Q9HA89|uniprotkb:B4DUR5|ensembl:ENSP00000303398.1	psi-mi:a0a2u2h346_yerpe(display_long)|uniprotkb:YPO2403(locus name)	psi-mi:mtbp_human(display_long)|uniprotkb:MTBP(gene name)|psi-mi:MTBP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857283|imex:IM-13779-6194	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010231(SUF system FeS cluster assembly, SufB)|interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|refseq:WP_002211808.1|go:""GO:0016226""(iron-sulfur cluster assembly)|interpro:IPR037284|refseq:YP_002347368.1|interpro:IPR045595"	"refseq:NP_071328.2|ensembl:ENSG00000172167.8(gene)|ensembl:ENST00000305949.6(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0007089""(traversing start control point of mitotic cell cycle)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0034501""(protein localization to kinetochore)|go:""GO:0045839""(negative regulation of mitotic nuclear division)|interpro:IPR029418|interpro:IPR029420|interpro:IPR029421|interpro:IPR039061|panther:PTHR14382(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DkCekEHB1T0D0zddmetEadbmVDk632	rogid:RSlztwxAJ2xqITEg3zeYQ8uQBUM9606	intact-crc:EB05CABD544103F5|rigid:T1OPLKov93ia8/0NDSmXYl/QG54	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H632	uniprotkb:Q8D068	intact:EBI-2857328	intact:EBI-2846153|uniprotkb:Q74VD0	psi-mi:q9h632_human(display_long)	psi-mi:q8d068_yerpe(display_long)|uniprotkb:uup3(gene name)|psi-mi:uup3(display_short)|uniprotkb:YP_1381(locus name)|uniprotkb:y2677(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857325|imex:IM-13779-6195	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR032781|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR050611"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DbQJZjZuz/8h5F3+SccnmfTBGZ09606	rogid:uq/st091dJjwV1JggBt3SaIlbSQ632	intact-crc:CBD23549616E3C2B|rigid:f2mxp+lov9/x20XrTjWmK8CH1SY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BRX5	uniprotkb:A0A380PL54	intact:EBI-2857315|uniprotkb:B2RDP3|uniprotkb:Q9H870|uniprotkb:E9PB21|ensembl:ENSP00000318196.6	intact:EBI-2847486|uniprotkb:Q74PZ0|uniprotkb:Q0WJM2|uniprotkb:Q7CG61|uniprotkb:A0A384KFY6	psi-mi:psf3_human(display_long)|uniprotkb:GINS3(gene name)|psi-mi:GINS3(display_short)|uniprotkb:PSF3(gene name synonym)|uniprotkb:GINS complex subunit 3(gene name synonym)	psi-mi:a0a380pl54_yerpe(display_long)|uniprotkb:b4388(gene name)|psi-mi:b4388(display_short)|uniprotkb:serB(gene name synonym)|uniprotkb:O-phosphoserine phosphohydrolase(gene name synonym)|uniprotkb:YPO0442(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857312|imex:IM-13779-6193	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001119601.1|refseq:NP_001119602.1|refseq:NP_073607.2|ensembl:ENSG00000181938.14(gene)|ensembl:ENST00000318129.6(transcript)|go:""GO:0000811""(GINS complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0071162""(CMG complex)|go:""GO:1902975""(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|interpro:IPR055221|mint:Q9BRX5|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:8B9D|rcsb pdb:8OK2|reactome:R-HSA-176974|dip:DIP-29333N|panther:PTHR22768(orthology-group)"	"interpro:IPR023214|refseq:WP_002209219.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006564""(L-serine biosynthetic process)|go:""GO:0036424""(L-phosphoserine phosphatase activity)|interpro:IPR036412|interpro:IPR041449|interpro:IPR004469(Phosphoserine phosphatase SerB)|refseq:YP_002345516.1|interpro:IPR050582|panther:PTHR43344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/14	rogid:3anXwRLIwu/t1G1v+P1yzhh7QqA9606	rogid:geOUaVXaO28Rw1OHbz2UDW1vFEg632	intact-crc:2AC5C8E071BEDAF9|rigid:Tc+O7+ms5ykhnZOKTstNCpqSAPc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5LE80	uniprotkb:Q9P2X3	intact:EBI-2844490	intact:EBI-2857352|uniprotkb:A8MXG0|uniprotkb:Q49AM0|uniprotkb:Q9H2X4|ensembl:ENSP00000284202.4	psi-mi:a0a3g5le80_yerpe(display_long)|uniprotkb:y0950(locus name)	psi-mi:impct_human(display_long)|uniprotkb:IMPACT(gene name)|psi-mi:IMPACT(display_short)|uniprotkb:Imprinted and ancient gene protein homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857359|imex:IM-13779-6199	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A2U2H2E6(uniprot-removed-ac)|refseq:WP_002214689.1	"refseq:NP_060909.1|ensembl:ENSG00000154059.11(gene)|ensembl:ENST00000284202.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0043022""(ribosome binding)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140469""(GCN2-mediated signaling)|go:""GO:1990138""(neuron projection extension)|go:""GO:1990611""(regulation of cytoplasmic translational initiation in response to stress)|interpro:IPR001498(Protein of unknown function UPF0029, N-terminal)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR020568|interpro:IPR020569|interpro:IPR023582|interpro:IPR036956|reactome:R-HSA-9633012|panther:PTHR16301(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/jucghU/x5u3xZ8tY3nE8V0qUNg632	rogid:8TKZjuF5JkplyjE2D+6HlvygE4U9606	intact-crc:703C89E88E80A804|rigid:g+TWDDYjMlZ9XiS6sg1Cz+t2M18	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H3U2	uniprotkb:Q8CL50	intact:EBI-2841307	intact:EBI-2857335	psi-mi:q9h3u2_human(display_long)|uniprotkb:smap-7(gene name)|psi-mi:smap-7(display_short)	psi-mi:q8cl50_yerpe(display_long)|uniprotkb:y2187(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857338|imex:IM-13779-6200	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:""GO:0005634""(nucleus)|interpro:IPR050717|interpro:IPR036236"	interpro:IPR045604	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8T0z+zfA5tGSiSDxfIYV2CR3E289606	rogid:jt6BQ8hZFhQrWjllEvfW2r4RX60632	intact-crc:28DE3CBC47D6009A|rigid:4lTQ6E0d00xOBsocsNq7gC6eSGs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H355	uniprotkb:P42713	intact:EBI-2801997	intact:EBI-2855318	psi-mi:q9h355_human(display_long)|uniprotkb:hCG_2018797(orf name)|uniprotkb:DKFZp686B0790(gene name)|psi-mi:DKFZp686B0790(display_short)	psi-mi:yscq_yerpe(display_long)|uniprotkb:yscQ(gene name)|psi-mi:yscQ(display_short)|uniprotkb:YPCD1.43(locus name)|uniprotkb:y5035(locus name)|uniprotkb:y0038(locus name)|uniprotkb:YP_pCD40(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857345|imex:IM-13779-6196	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"refseq:NP_395177.1|refseq:NP_857739.1|refseq:NP_857934.1|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|interpro:IPR003283(Type III secretion system outer membrane O protein)|interpro:IPR013385(Type III secretion system apparatus protein YscQ/HrcQ)|refseq:WP_002212948.1|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0071978""(bacterial-type flagellum-dependent swarming motility)|interpro:IPR036429|panther:PTHR30034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M/QkNnPcTQThExIo8qiGSEwgAls9606	rogid:6QCEVIThofNCQV+S/cN32USA1WE632	intact-crc:FFE21ED3B8EA9BD8|rigid:mATutdFtNtciAmFy3em2VqD2nl4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1Q0	uniprotkb:Q9Y520	intact:EBI-2842423	intact:EBI-2685847|uniprotkb:Q05DM8|uniprotkb:Q9HA05|uniprotkb:Q9UF29|uniprotkb:Q9NSM8|uniprotkb:Q9H2N2|uniprotkb:Q9NXL3|uniprotkb:Q6PD54|uniprotkb:Q49A39|uniprotkb:Q9UPQ6|intact:EBI-2824421	psi-mi:q8d1q0_yerpe(display_long)|uniprotkb:gabD(gene name)|psi-mi:gabD(display_short)|uniprotkb:gabD_1(gene name synonym)|uniprotkb:NCTC5923_00695(orf name)|uniprotkb:y0176(locus name)	psi-mi:prc2c_human(display_long)|uniprotkb:BAT2D1(gene name synonym)|uniprotkb:KIAA1096(gene name synonym)|uniprotkb:XTP2(gene name synonym)|uniprotkb:BAT2 domain-containing protein 1(gene name synonym)|uniprotkb:HBV X-transactivated gene 2 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 2-like 2(gene name synonym)|uniprotkb:PRRC2C(gene name)|psi-mi:PRRC2C(display_short)|uniprotkb:BAT2L2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2C(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857373|imex:IM-13779-6198	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR029510|go:""GO:0036243""(""succinate-semialdehyde dehydrogenase (NADP+) activity"")|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR050740"	"refseq:NP_055987.2|refseq:XP_006711301.1|refseq:XP_005245074.1|dip:DIP-47285N|mint:Q9Y520|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0034063""(stress granule assembly)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|panther:PTHR14038(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:txdyWoCIYMZColLNszJEOPdNYNk632	rogid:qecMuJHnm8n95OFpT+m+i9JbBoo9606	intact-crc:4E63CC321969EDCC|rigid:+SWOdDOcTe8oCN+OCHPTQh87cUw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y520	uniprotkb:Q8ZGR6	intact:EBI-2685847|uniprotkb:Q05DM8|uniprotkb:Q9HA05|uniprotkb:Q9UF29|uniprotkb:Q9NSM8|uniprotkb:Q9H2N2|uniprotkb:Q9NXL3|uniprotkb:Q6PD54|uniprotkb:Q49A39|uniprotkb:Q9UPQ6|intact:EBI-2824421	intact:EBI-2844456|uniprotkb:Q0WHI9	psi-mi:prc2c_human(display_long)|uniprotkb:BAT2D1(gene name synonym)|uniprotkb:KIAA1096(gene name synonym)|uniprotkb:XTP2(gene name synonym)|uniprotkb:BAT2 domain-containing protein 1(gene name synonym)|uniprotkb:HBV X-transactivated gene 2 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 2-like 2(gene name synonym)|uniprotkb:PRRC2C(gene name)|psi-mi:PRRC2C(display_short)|uniprotkb:BAT2L2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2C(gene name synonym)	psi-mi:ubig_yerpe(display_long)|uniprotkb:ubiG(gene name)|psi-mi:ubiG(display_short)|uniprotkb:2-polyprenyl-6-hydroxyphenol methylase(gene name synonym)|uniprotkb:3-demethylubiquinone 3-O-methyltransferase(gene name synonym)|uniprotkb:YPO1215(locus name)|uniprotkb:YP_0922(locus name)|uniprotkb:y2973(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857366|imex:IM-13779-6197	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055987.2|refseq:XP_006711301.1|refseq:XP_005245074.1|dip:DIP-47285N|mint:Q9Y520|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0034063""(stress granule assembly)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|panther:PTHR14038(orthology-group)"	"interpro:IPR029063|interpro:IPR010233(Ubiquinone biosynthesis O-methyltransferase)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0010420""(polyprenyldihydroxybenzoate methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0061542""(3-demethylubiquinol 3-O-methyltransferase activity)|go:""GO:0102208""(2-polyprenyl-6-hydroxyphenol methylase activity)|refseq:WP_002210820.1|refseq:YP_002346249.1|panther:PTHR43464(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qecMuJHnm8n95OFpT+m+i9JbBoo9606	rogid:HQ8DZ/0XF59YGNXPYkTGaS2XvHQ632	intact-crc:F97EAEC913063D21|rigid:aPYv5Lxtp8bX+Fd7xc1ULLoIj88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1M2	uniprotkb:Q9Y520	intact:EBI-2849599|uniprotkb:Q74Y66	intact:EBI-2685847|uniprotkb:Q05DM8|uniprotkb:Q9HA05|uniprotkb:Q9UF29|uniprotkb:Q9NSM8|uniprotkb:Q9H2N2|uniprotkb:Q9NXL3|uniprotkb:Q6PD54|uniprotkb:Q49A39|uniprotkb:Q9UPQ6|intact:EBI-2824421	psi-mi:q8d1m2_yerpe(display_long)|uniprotkb:acrA1(gene name)|psi-mi:acrA1(display_short)|uniprotkb:YP_0101(locus name)|uniprotkb:y0287(locus name)	psi-mi:prc2c_human(display_long)|uniprotkb:BAT2D1(gene name synonym)|uniprotkb:KIAA1096(gene name synonym)|uniprotkb:XTP2(gene name synonym)|uniprotkb:BAT2 domain-containing protein 1(gene name synonym)|uniprotkb:HBV X-transactivated gene 2 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 2-like 2(gene name synonym)|uniprotkb:PRRC2C(gene name)|psi-mi:PRRC2C(display_short)|uniprotkb:BAT2L2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2C(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857380|imex:IM-13779-6201	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006144(Secretion protein HlyD, conserved site)|interpro:IPR011053(Single hybrid motif)|go:""GO:0009306""(protein secretion)|go:""GO:0016020""(membrane)|interpro:IPR050739"	"refseq:NP_055987.2|refseq:XP_006711301.1|refseq:XP_005245074.1|dip:DIP-47285N|mint:Q9Y520|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0034063""(stress granule assembly)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|panther:PTHR14038(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:81koSqzmbeM9XH9qVt8tsKLcazY632	rogid:qecMuJHnm8n95OFpT+m+i9JbBoo9606	intact-crc:1A7555D0D429ED0C|rigid:V9zS61yzCe6JWWTLOIKB6bVkre0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H1C8	uniprotkb:A0A0H2W174	intact:EBI-2824460	intact:EBI-2857409|uniprotkb:Q74WU9|uniprotkb:A0A3N4BLR1|uniprotkb:Q7CK49|uniprotkb:Q0WC84	psi-mi:q9h1c8_human(display_long)	psi-mi:a0a0h2w174_yerpe(display_long)|uniprotkb:malZ(gene name)|psi-mi:malZ(display_short)|uniprotkb:YPO3200(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857406|imex:IM-13779-6203	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|interpro:IPR007677(DFNA5 protein)|interpro:IPR041263"	"interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004185(Glycoside hydrolase, family 13, N-terminal Ig-like region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017069(Maltodextrin glucosidase)|refseq:WP_002208678.1|go:""GO:0004558""(alpha-1,4-glucosidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:YP_002348104.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:z3qFWwBlJxH9pCmOB/Hljm5yZC09606	rogid:xXWAIuIiT4Lo4aYGy1vcRouNeV4632	intact-crc:7EDACC36EBC32D7C|rigid:BxFst+h0NlfnGQ/hIQvcLi3OWjg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHH3	uniprotkb:Q9Y520	intact:EBI-2857394|uniprotkb:Q0WIB9	intact:EBI-2685847|uniprotkb:Q05DM8|uniprotkb:Q9HA05|uniprotkb:Q9UF29|uniprotkb:Q9NSM8|uniprotkb:Q9H2N2|uniprotkb:Q9NXL3|uniprotkb:Q6PD54|uniprotkb:Q49A39|uniprotkb:Q9UPQ6|intact:EBI-2824421	psi-mi:pgk_yerpe(display_long)|uniprotkb:pgk(gene name)|psi-mi:pgk(display_short)|uniprotkb:YPO0921(locus name)|uniprotkb:y3308(locus name)|uniprotkb:YP_3519(locus name)	psi-mi:prc2c_human(display_long)|uniprotkb:BAT2D1(gene name synonym)|uniprotkb:KIAA1096(gene name synonym)|uniprotkb:XTP2(gene name synonym)|uniprotkb:BAT2 domain-containing protein 1(gene name synonym)|uniprotkb:HBV X-transactivated gene 2 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 2-like 2(gene name synonym)|uniprotkb:PRRC2C(gene name)|psi-mi:PRRC2C(display_short)|uniprotkb:BAT2L2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2C(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857399|imex:IM-13779-6202	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|refseq:WP_002209963.1|go:""GO:0004618""(phosphoglycerate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0043531""(ADP binding)|interpro:IPR036043|refseq:YP_002345969.1|panther:PTHR11406(orthology-group)"	"refseq:NP_055987.2|refseq:XP_006711301.1|refseq:XP_005245074.1|dip:DIP-47285N|mint:Q9Y520|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0034063""(stress granule assembly)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|panther:PTHR14038(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NB2BLC2gD2al0+rea01wVtP5/iU632	rogid:qecMuJHnm8n95OFpT+m+i9JbBoo9606	intact-crc:D3C1D77E1B9EECCF|rigid:aUMtI+QZ+dUz/y02I7XNZhs/CBc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H2G1	uniprotkb:A6NC98	intact:EBI-2857421|uniprotkb:Q74Y18|uniprotkb:Q0WKD8|uniprotkb:Q7CFV8|uniprotkb:A0A384LDE1	intact:EBI-347573|uniprotkb:B5MDM2|ensembl:ENSP00000349238.5|uniprotkb:A5D8Y5|uniprotkb:Q05BL2|uniprotkb:Q6RUV3|uniprotkb:Q8N1Q6|uniprotkb:Q8NF44|uniprotkb:Q9H0H1|intact:EBI-2802028	psi-mi:a0a2u2h2g1_yerpe(display_long)|uniprotkb:YPO0164(locus name)	psi-mi:cc88b_human(display_long)|uniprotkb:CCDC88B(gene name)|psi-mi:CCDC88B(display_short)|uniprotkb:BRLZ(gene name synonym)|uniprotkb:Brain leucine zipper domain-containing protein(gene name synonym)|uniprotkb:Hook-related protein 3(gene name synonym)|uniprotkb:Gipie(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857418|imex:IM-13779-6205	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR010100(TonB-dependent copper receptor)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|refseq:WP_002208882.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015344""(siderophore uptake transmembrane transporter activity)|go:""GO:0044718""(siderophore transmembrane transport)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002345250.1|panther:PTHR30069(orthology-group)"	"ensembl:ENSG00000168071.22(gene)|ensembl:ENST00000356786.10(transcript)|go:""GO:0001819""(positive regulation of cytokine production)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0008017""(microtubule binding)|go:""GO:0016020""(membrane)|go:""GO:0030705""(cytoskeleton-dependent intracellular transport)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042832""(defense response to protozoan)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051959""(dynein light intermediate chain binding)|interpro:IPR036872|interpro:IPR043936|mint:A6NC98|refseq:NP_115627.6|panther:PTHR18947(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OF3HwYfg6zaTqz0HTQ2WdTZ5Dv4632	rogid:s3J2pQABqQHFONLVjshSCCTTmSc9606	intact-crc:12BE95AD14CC0DA1|rigid:ZrD2wCkSlDTzvf6Jd/T60ut7z8U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y520	uniprotkb:A0A0H2W2N9	intact:EBI-2685847|uniprotkb:Q05DM8|uniprotkb:Q9HA05|uniprotkb:Q9UF29|uniprotkb:Q9NSM8|uniprotkb:Q9H2N2|uniprotkb:Q9NXL3|uniprotkb:Q6PD54|uniprotkb:Q49A39|uniprotkb:Q9UPQ6|intact:EBI-2824421	intact:EBI-2840467|uniprotkb:Q74XT4|uniprotkb:Q0WBR4|uniprotkb:A0A384L498|uniprotkb:Q7CKD3|uniprotkb:A0A3N4B9W7	psi-mi:prc2c_human(display_long)|uniprotkb:BAT2D1(gene name synonym)|uniprotkb:KIAA1096(gene name synonym)|uniprotkb:XTP2(gene name synonym)|uniprotkb:BAT2 domain-containing protein 1(gene name synonym)|uniprotkb:HBV X-transactivated gene 2 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 2-like 2(gene name synonym)|uniprotkb:PRRC2C(gene name)|psi-mi:PRRC2C(display_short)|uniprotkb:BAT2L2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2C(gene name synonym)	psi-mi:a0a0h2w2n9_yerpe(display_long)|uniprotkb:degP(gene name)|psi-mi:degP(display_short)|uniprotkb:gsrA(gene name synonym)|uniprotkb:htrA(gene name synonym)|uniprotkb:ptd(gene name synonym)|uniprotkb:YPO3382(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857387|imex:IM-13779-6204	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055987.2|refseq:XP_006711301.1|refseq:XP_005245074.1|dip:DIP-47285N|mint:Q9Y520|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0034063""(stress granule assembly)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|panther:PTHR14038(orthology-group)"	"interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:WP_002209370.1|refseq:YP_002348274.1|interpro:IPR036034"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qecMuJHnm8n95OFpT+m+i9JbBoo9606	rogid:wh5TqHAdstARdvvFDyS2kqzSnxY632	intact-crc:75B625C00FF4E9F2|rigid:S2cxuQZfvuSHQMdmTCOJWMrMrUI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZU9	uniprotkb:Q9C0D7	intact:EBI-2841714	intact:EBI-2857430|uniprotkb:B4DI65|uniprotkb:B4DR47|ensembl:ENSP00000278590.3	psi-mi:q8czu9_yerpe(display_long)|uniprotkb:y3342(locus name)	psi-mi:zc12c_human(display_long)|uniprotkb:ZC3H12C(gene name)|psi-mi:ZC3H12C(display_short)|uniprotkb:KIAA1726(gene name synonym)|uniprotkb:MCPIP3(gene name synonym)|uniprotkb:MCP-induced protein 3(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12C(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857434|imex:IM-13779-6208	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR002491(Periplasmic binding protein)|interpro:IPR050902	"refseq:NP_203748.1|refseq:XP_016873966.1|ensembl:ENSG00000149289.11(gene)|ensembl:ENST00000278590.8(transcript)|go:""GO:0003729""(mRNA binding)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR021869|interpro:IPR040546|interpro:IPR040757|interpro:IPR051101|panther:PTHR12876(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:61Vn/X9ZzrY6cGaSgyM0HeClZVc632	rogid:gfS1g0G2iiUk51BN1J7yoWQtyb09606	intact-crc:DAC3D6FB9538021F|rigid:oGIblapHBRyVDSwIUT89+rKYOe8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BUD9	uniprotkb:Q8ZIG9	intact:EBI-2815091	intact:EBI-2841314|uniprotkb:Q0WJD4	psi-mi:q9bud9_human(display_long)|uniprotkb:AAK1(gene name)|psi-mi:AAK1(display_short)|uniprotkb:Adaptor-associated kinase 1(gene name synonym)	psi-mi:leu3_yerpe(display_long)|uniprotkb:leuB(gene name)|psi-mi:leuB(display_short)|uniprotkb:3-IPM-DH(gene name synonym)|uniprotkb:Beta-IPM dehydrogenase(gene name synonym)|uniprotkb:YPO0532(locus name)|uniprotkb:y3646(locus name)|uniprotkb:YP_3650(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857464|imex:IM-13779-6209	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR051744|go:""GO:0004672""(protein kinase activity)|go:""GO:0005524""(ATP binding)"	"interpro:IPR019818|interpro:IPR024084|interpro:IPR004429(3-isopropylmalate dehydrogenase)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003862""(3-isopropylmalate dehydrogenase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0051287""(NAD binding)|refseq:WP_002210454.1|panther:PTHR42979(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:omcMYHQW8TuItDu+/qaLSXo1X109606	rogid:reEfvgdNZvA05yp9jIBUEmyL2/o632	intact-crc:03BFE7376E08B6BA|rigid:zg7OkkMni/PQ7bLHzdZjCBNSgZs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCG1	uniprotkb:Q7CIA2	intact:EBI-2857453|intact:EBI-3922135|uniprotkb:Q14589|uniprotkb:Q504Q8|uniprotkb:Q96JC5|uniprotkb:Q9BVY9|uniprotkb:Q9H7N6|ensembl:ENSP00000406201.1|ensembl:ENSP00000409597.1|ensembl:ENSP00000470961.1|ensembl:ENSP00000507845.1	intact:EBI-2849892|uniprotkb:Q74U75	psi-mi:zn160_human(display_long)|uniprotkb:ZNF160(gene name)|psi-mi:ZNF160(display_short)|uniprotkb:KIAA1611(gene name synonym)|uniprotkb:Zinc finger protein HZF5(gene name synonym)|uniprotkb:Zinc finger protein Kr18(gene name synonym)	"psi-mi:prmc_yerpe(display_long)|uniprotkb:N5-glutamine methyltransferase PrmC(gene name synonym)|uniprotkb:""Protein-(glutamine-N5) MTase PrmC""(gene name synonym)|uniprotkb:Protein-glutamine N-methyltransferase PrmC(gene name synonym)|uniprotkb:hemK(gene name synonym)|uniprotkb:YPO2018(locus name)|uniprotkb:YP_1866(locus name)|uniprotkb:y2289(locus name)|uniprotkb:prmC(gene name)|psi-mi:prmC(display_short)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857457|imex:IM-13779-6207	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001309055.1|refseq:NP_001309054.1|refseq:NP_001096073.1|refseq:NP_150630.2|refseq:NP_942596.1|refseq:NP_001309057.1|refseq:NP_001309058.1|refseq:NP_001309059.1|refseq:NP_001309060.1|refseq:NP_001309061.1|refseq:NP_001309062.1|refseq:NP_001309063.1|refseq:NP_001309064.1|refseq:NP_001309065.1|refseq:XP_016882935.1|refseq:XP_016882937.1|ensembl:ENSG00000170949.18(gene)|ensembl:ENST00000418871.5(transcript)|ensembl:ENST00000429604.5(transcript)|ensembl:ENST00000599056.5(transcript)|ensembl:ENST00000683776.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0030097""(hemopoiesis)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR050527|reactome:R-HSA-212436|panther:PTHR24377(orthology-group)"	"interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004556(Modification methylase HemK)|interpro:IPR019874|interpro:IPR025714|interpro:IPR029063|refseq:WP_002211235.1|interpro:IPR040758|go:""GO:0003676""(nucleic acid binding)|go:""GO:0006415""(translational termination)|go:""GO:0032259""(methylation)|go:""GO:0036009""(protein-glutamine N-methyltransferase activity)|go:""GO:0102559""(""peptide chain release factor N(5)-glutamine methyltransferase activity"")|refseq:YP_002347004.1|interpro:IPR050320|panther:PTHR18895(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Q2G1Ettvdkbgz8bHt2bmZzOPRjg9606	rogid:THdPGJ4n/c8dQ78xq18i7nKkalc632	intact-crc:6F8CAEAE1937369E|rigid:V9Jkd/KAJjjgHm+Q/0M1yLwNPjs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0F3	uniprotkb:Q9BW66	intact:EBI-2857441|uniprotkb:Q74U42	intact:EBI-739784|uniprotkb:F5H8A7|uniprotkb:Q9NPF9|uniprotkb:F5H7P3|ensembl:ENSP00000216756.6|ensembl:ENSP00000453839.1	psi-mi:q8d0f3_yerpe(display_long)|uniprotkb:YP_1909(locus name)|uniprotkb:zwf(gene name)|psi-mi:zwf(display_short)|uniprotkb:y2244(locus name)	psi-mi:cinp_human(display_long)|uniprotkb:CINP(gene name)|psi-mi:CINP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857446|imex:IM-13779-6206	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001282(Glucose-6-phosphate dehydrogenase)|interpro:IPR019796|interpro:IPR022675|interpro:IPR022674|go:""GO:0004345""(glucose-6-phosphate dehydrogenase activity)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0050661""(NADP binding)|interpro:IPR036291"	"refseq:NP_116019.1|refseq:NP_001306975.1|ensembl:ENSG00000100865.15(gene)|ensembl:ENST00000216756.11(transcript)|ensembl:ENST00000559514.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0051301""(cell division)|go:""GO:1990275""(preribosome binding)|interpro:IPR023250|rcsb pdb:8CIH|rcsb pdb:8RHN|dip:DIP-49011N|panther:PTHR15827(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/25	rogid:zLDFatEkJiffqgaqH3wUOVQ57s8632	rogid:SOPi9nufGbexSPzMJCFPgmJrd/o9606	intact-crc:118DD1A07C6C1F12|rigid:nEbcn9XMudvE77T08hN89nOVMN0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKB2	uniprotkb:Q9BRW1	intact:EBI-2857486	intact:EBI-2857489	psi-mi:q8ckb2_yerpe(display_long)|uniprotkb:y3797(locus name)	psi-mi:q9brw1_human(display_long)|uniprotkb:EVI2B(gene name)|psi-mi:EVI2B(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857493|imex:IM-13779-6210	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR052934|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)"	"interpro:IPR033239|refseq:NP_006486.3|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5sqSFEOPSOBD89B6HPwdhZkqANc632	rogid:cU7SD08w8WVY+ORpQmV/YJWGj7Q9606	intact-crc:53B3FCD1D8E8FF55|rigid:YmsmsWKKGdp6K5dY4+YCEIcKn9c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PLH1	uniprotkb:Q9BQ83	intact:EBI-2856592|uniprotkb:Q74X46|uniprotkb:Q7CKH1|uniprotkb:A0A0H2W2R5	intact:EBI-2370858|uniprotkb:Q6NTG6|uniprotkb:B7ZME1|ensembl:ENSP00000251303.7|ensembl:ENSP00000328940.5	psi-mi:a0a2s9plh1_yerpe(display_long)|uniprotkb:YPO3468(locus name)	psi-mi:slx1_human(display_long)|uniprotkb:GIYD1(gene name synonym)|uniprotkb:GIYD2(gene name synonym)|uniprotkb:SLX1(gene name synonym)|uniprotkb:GIY-YIG domain-containing protein 1(gene name synonym)|uniprotkb:SLX1A(gene name)|psi-mi:SLX1A(display_short)|uniprotkb:SLX1B(gene name)|psi-mi:SLX1B(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857519|imex:IM-13779-6212	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002209281.1|interpro:IPR008397(Alginate lyase)|interpro:IPR008929(Chondroitin AC/alginate lyase)|go:""GO:0016829""(lyase activity)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348357.1"	"ensembl:ENSG00000132207.19(gene)|ensembl:ENSG00000181625.18(gene)|ensembl:ENST00000251303.11(transcript)|ensembl:ENST00000330181.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0008821""(crossover junction DNA endonuclease activity)|go:""GO:0010792""(DNA double-strand break processing involved in repair via single-strand annealing)|go:""GO:0010833""(telomere maintenance via telomere lengthening)|go:""GO:0017108""(5'-flap endonuclease activity)|go:""GO:0033557""(Slx1-Slx4 complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0061820""(telomeric D-loop disassembly)|go:""GO:0090656""(t-circle formation)|go:""GO:1904357""(negative regulation of telomere maintenance via telomere lengthening)|go:""GO:1904431""(positive regulation of t-circle formation)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR027520|interpro:IPR035901|interpro:IPR048749|interpro:IPR050381|reactome:R-HSA-5693568|reactome:R-HSA-6783310|refseq:NP_001014999.1|refseq:NP_001015000.1|refseq:NP_076949.1|refseq:NP_835145.1|panther:PTHR20208(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XJauDb6vvXdcLKHXeXt+Js2URk8632	rogid:HOCvski3UnUW86f0rfOUf8fTQ8c9606	intact-crc:8A49E7F4333EC04E|rigid:aYd+XymFC3FFl9mccF0c5SYj71E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W3E3	uniprotkb:Q9BRW1	intact:EBI-2857500|uniprotkb:Q74VI6|uniprotkb:A0A2S9PI91|uniprotkb:Q7CHC8|uniprotkb:Q0WHE2	intact:EBI-2857489	psi-mi:a0a0h2w3e3_yerpe(display_long)|uniprotkb:bcr(gene name)|psi-mi:bcr(display_short)|uniprotkb:bicA(gene name synonym)|uniprotkb:bicR(gene name synonym)|uniprotkb:sur(gene name synonym)|uniprotkb:suxA(gene name synonym)|uniprotkb:YPO1267(locus name)	psi-mi:q9brw1_human(display_long)|uniprotkb:EVI2B(gene name)|psi-mi:EVI2B(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857505|imex:IM-13779-6213	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020846|interpro:IPR004812(Drug resistance transporter Bcr/CflA subfamily)|interpro:IPR011701(Major facilitator superfamily MFS-1)|refseq:WP_002208831.1|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR036259|refseq:YP_002346296.1"	"interpro:IPR033239|refseq:NP_006486.3|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:455JF+n6Oe6dlqZUuclJ+1lby2U632	rogid:cU7SD08w8WVY+ORpQmV/YJWGj7Q9606	intact-crc:2B8D3536C140632D|rigid:E8InIhqKZMEOcG2SQi2NI/0Db5w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GZL1	uniprotkb:Q9BQ83	intact:EBI-2854458|uniprotkb:Q74PS2|uniprotkb:Q0WB90|uniprotkb:A0A5P8YJZ1|uniprotkb:Q7CL96|uniprotkb:A0A384KMD8	intact:EBI-2370858|uniprotkb:Q6NTG6|uniprotkb:B7ZME1|ensembl:ENSP00000251303.7|ensembl:ENSP00000328940.5	psi-mi:a0a2u2gzl1_yerpe(display_long)|uniprotkb:pog(gene name)|psi-mi:pog(display_short)|uniprotkb:ssp(gene name synonym)|uniprotkb:sspA(gene name synonym)|uniprotkb:YPO3561(locus name)	psi-mi:slx1_human(display_long)|uniprotkb:GIYD1(gene name synonym)|uniprotkb:GIYD2(gene name synonym)|uniprotkb:SLX1(gene name synonym)|uniprotkb:GIY-YIG domain-containing protein 1(gene name synonym)|uniprotkb:SLX1A(gene name)|psi-mi:SLX1A(display_short)|uniprotkb:SLX1B(gene name)|psi-mi:SLX1B(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857512|imex:IM-13779-6211	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050983|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|rcsb pdb:1YY7|refseq:WP_002210135.1|interpro:IPR034341|interpro:IPR040079|interpro:IPR036249|interpro:IPR036282|refseq:YP_002348448.1|interpro:IPR034342	"ensembl:ENSG00000132207.19(gene)|ensembl:ENSG00000181625.18(gene)|ensembl:ENST00000251303.11(transcript)|ensembl:ENST00000330181.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0008821""(crossover junction DNA endonuclease activity)|go:""GO:0010792""(DNA double-strand break processing involved in repair via single-strand annealing)|go:""GO:0010833""(telomere maintenance via telomere lengthening)|go:""GO:0017108""(5'-flap endonuclease activity)|go:""GO:0033557""(Slx1-Slx4 complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0061820""(telomeric D-loop disassembly)|go:""GO:0090656""(t-circle formation)|go:""GO:1904357""(negative regulation of telomere maintenance via telomere lengthening)|go:""GO:1904431""(positive regulation of t-circle formation)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR027520|interpro:IPR035901|interpro:IPR048749|interpro:IPR050381|reactome:R-HSA-5693568|reactome:R-HSA-6783310|refseq:NP_001014999.1|refseq:NP_001015000.1|refseq:NP_076949.1|refseq:NP_835145.1|panther:PTHR20208(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9smmAt4ZQb55TC9gx1z1tyl4bTI632	rogid:HOCvski3UnUW86f0rfOUf8fTQ8c9606	intact-crc:B2CEB9884448851C|rigid:Q0jfRFOr2Fsunz2eWvMkwcWDqiQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYS8	uniprotkb:Q6NTE8	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	intact:EBI-2857471|uniprotkb:Q9UN54|uniprotkb:B5MD09|uniprotkb:Q7Z3D8|uniprotkb:Q9BUC1|uniprotkb:E9PAK6|ensembl:ENSP00000292586.6|ensembl:ENSP00000491991.1|intact:EBI-28972029	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	psi-mi:mrnip_human(display_long)|uniprotkb:MRNIP(gene name)|psi-mi:MRNIP(display_short)|uniprotkb:C5orf45(gene name synonym)|uniprotkb:MRN-interacting protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857479|imex:IM-13779-6214	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	"refseq:NP_001017987.1|refseq:NP_057259.2|ensembl:ENSG00000161010.16(gene)|ensembl:ENSG00000283918.2(gene)|ensembl:ENST00000292586.11(transcript)|ensembl:ENST00000639632.2(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0006974""(DNA damage response)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0010212""(response to ionizing radiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0071168""(protein localization to chromatin)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2001032""(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR032739|interpro:IPR049472|mint:Q6NTE8|panther:PTHR15863(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	rogid:CrsM09JAVJR3E6yo2BT4fxwV5yQ9606	intact-crc:0F9A8CE010E2FAEA|rigid:LjJqLbBQepo3BrAhOCPIf1YevxI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A7D9NLK2	uniprotkb:Q96LM7	intact:EBI-2842776	intact:EBI-2796677|ensembl:ENSP00000375732.2	psi-mi:a0a7d9nlk2_yerpe(display_long)|uniprotkb:ORF99(gene name)|psi-mi:ORF99(display_short)|uniprotkb:Y1060(locus name)	psi-mi:q96lm7_human(display_long)|uniprotkb:CD37(gene name)|psi-mi:CD37(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857547|imex:IM-13779-6217	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002224265.1|refseq:YP_093964.1|uniprotkb:A0A5K1VD91(uniprot-removed-ac)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"ensembl:ENSG00000104894.12(gene)|ensembl:ENST00000391859.6(transcript)|go:""GO:0016020""(membrane)|interpro:IPR018499|interpro:IPR018503"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:drpdmgWm7Xi1tzOHiVuDwatPqrI632	rogid:tcTp+2kI1f21WZWslX4/BwTVp549606	intact-crc:E31C888CBD5A5465|rigid:+JHfPydqTsmlMOLK5Lcshn3k23s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6GPH4	uniprotkb:P17778	intact:EBI-2815120|uniprotkb:Q99982|uniprotkb:A8K9Y3|uniprotkb:A2T932|uniprotkb:Q8N557|uniprotkb:Q6MZE8|uniprotkb:A8K2L1|uniprotkb:A2T931|uniprotkb:D3DTM6|ensembl:ENSP00000354822.3	intact:EBI-2842665|uniprotkb:O68701	psi-mi:xaf1_human(display_long)|uniprotkb:XAF1(gene name)|psi-mi:XAF1(display_short)|uniprotkb:BIRC4BP(gene name synonym)|uniprotkb:XIAPAF1(gene name synonym)|uniprotkb:BIRC4-binding protein(gene name synonym)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857533|imex:IM-13779-6218	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_059993.2|refseq:NP_954590.1|refseq:XP_005256765.1|ensembl:ENSG00000132530.17(gene)|ensembl:ENST00000361842.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0140313""(molecular sequestering activity)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031220|interpro:IPR041386|interpro:IPR049439|interpro:IPR051986|rcsb pdb:2LXW|reactome:R-HSA-909733|panther:PTHR16295(orthology-group)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mq5cxYJeNJw2RyYn05nfTS/s5gI9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:5E9A5EE8866EC1FE|rigid:Jc9J2kRUgFd9GTSg8SrDUNuCbLU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BQ83	uniprotkb:A0A2S9PLB3	intact:EBI-2370858|uniprotkb:Q6NTG6|uniprotkb:B7ZME1|ensembl:ENSP00000251303.7|ensembl:ENSP00000328940.5	intact:EBI-2852501|uniprotkb:Q74Q16|uniprotkb:Q0WJJ2|uniprotkb:Q7CG79|uniprotkb:A0A384LE02	psi-mi:slx1_human(display_long)|uniprotkb:GIYD1(gene name synonym)|uniprotkb:GIYD2(gene name synonym)|uniprotkb:SLX1(gene name synonym)|uniprotkb:GIY-YIG domain-containing protein 1(gene name synonym)|uniprotkb:SLX1A(gene name)|psi-mi:SLX1A(display_short)|uniprotkb:SLX1B(gene name)|psi-mi:SLX1B(display_short)	psi-mi:a0a2s9plb3_yerpe(display_long)|uniprotkb:b0025(gene name)|psi-mi:b0025(display_short)|uniprotkb:ribF(gene name synonym)|uniprotkb:YPO0474(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857526|imex:IM-13779-6215	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000132207.19(gene)|ensembl:ENSG00000181625.18(gene)|ensembl:ENST00000251303.11(transcript)|ensembl:ENST00000330181.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0008821""(crossover junction DNA endonuclease activity)|go:""GO:0010792""(DNA double-strand break processing involved in repair via single-strand annealing)|go:""GO:0010833""(telomere maintenance via telomere lengthening)|go:""GO:0017108""(5'-flap endonuclease activity)|go:""GO:0033557""(Slx1-Slx4 complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0061820""(telomeric D-loop disassembly)|go:""GO:0090656""(t-circle formation)|go:""GO:1904357""(negative regulation of telomere maintenance via telomere lengthening)|go:""GO:1904431""(positive regulation of t-circle formation)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR027520|interpro:IPR035901|interpro:IPR048749|interpro:IPR050381|reactome:R-HSA-5693568|reactome:R-HSA-6783310|refseq:NP_001014999.1|refseq:NP_001015000.1|refseq:NP_076949.1|refseq:NP_835145.1|panther:PTHR20208(orthology-group)"	"refseq:WP_002210510.1|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR015864(FAD synthetase)|interpro:IPR023468|interpro:IPR002606(Riboflavin kinase/FAD synthetase)|interpro:IPR015865(Riboflavin kinase)|interpro:IPR023465|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|go:""GO:0003919""(FMN adenylyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006747""(FAD biosynthetic process)|go:""GO:0006771""(riboflavin metabolic process)|go:""GO:0008531""(riboflavin kinase activity)|go:""GO:0009231""(riboflavin biosynthetic process)|go:""GO:0009398""(FMN biosynthetic process)|refseq:YP_002345546.1|panther:PTHR22749(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HOCvski3UnUW86f0rfOUf8fTQ8c9606	rogid:0cLBPOUE8nJw1J+/mrY5ir7KpXU632	intact-crc:A3673E25286955EC|rigid:ywcWdfPc2Gx7P4khCcbVmwjGoyM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96LM7	uniprotkb:Q9Z375	intact:EBI-2796677|ensembl:ENSP00000375732.2	intact:EBI-2852829|uniprotkb:Q7CI43|uniprotkb:Q74UQ2|uniprotkb:A0A0H2W3B1|uniprotkb:A0A1U8QVE0|uniprotkb:A0A3N4B1F0	psi-mi:q96lm7_human(display_long)|uniprotkb:CD37(gene name)|psi-mi:CD37(display_short)	psi-mi:q9z375_yerpe(display_long)|uniprotkb:irp7(gene name)|psi-mi:irp7(display_short)|uniprotkb:ybtQ(gene name synonym)|uniprotkb:YPO1914(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857540|imex:IM-13779-6216	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000104894.12(gene)|ensembl:ENST00000391859.6(transcript)|go:""GO:0016020""(membrane)|interpro:IPR018499|interpro:IPR018503"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_002212761.1|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR036640|refseq:YP_002346905.1|interpro:IPR039421|panther:PTHR24222(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tcTp+2kI1f21WZWslX4/BwTVp549606	rogid:aJ6y5toJ2mfcSS+lal5tKlKh1Jk632	intact-crc:C404550008E80917|rigid:GT+OOiOETf15mEPxjYfCtNdNtMo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96LM7	uniprotkb:A0A5P8YFD8	intact:EBI-2796677|ensembl:ENSP00000375732.2	intact:EBI-2844797|uniprotkb:Q74TW8|uniprotkb:A0A0H2W658|uniprotkb:Q7CIM3|uniprotkb:A0A384L807	psi-mi:q96lm7_human(display_long)|uniprotkb:CD37(gene name)|psi-mi:CD37(display_short)	psi-mi:a0a5p8yfd8_yerpe(display_long)|uniprotkb:trpE(gene name)|psi-mi:trpE(display_short)|uniprotkb:YPO2208(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857554|imex:IM-13779-6219	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000104894.12(gene)|ensembl:ENST00000391859.6(transcript)|go:""GO:0016020""(membrane)|interpro:IPR018499|interpro:IPR018503"	"interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR019999|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR005257(Anthranilate synthase component I, TrpE)|interpro:IPR015890(Chorismate binding, C-terminal)|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004049""(anthranilate synthase activity)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347179.1|panther:PTHR11236(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tcTp+2kI1f21WZWslX4/BwTVp549606	rogid:4yY3KOTpkixAVvXxxbToZJUfRYM632	intact-crc:29C3008837DF01A9|rigid:PMlXcTyL1sqVKEFiARBmN2piGgg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99435	uniprotkb:Q8ZCW0	intact:EBI-946274|intact:EBI-2845314|uniprotkb:B7Z2U7|uniprotkb:B7Z5Q4|uniprotkb:B7Z9J5|uniprotkb:B7Z9U3|uniprotkb:Q96JS2|ensembl:ENSP00000390680.2|ensembl:ENSP00000394612.2	intact:EBI-2842923|uniprotkb:Q7CJK9|uniprotkb:Q0WD52|uniprotkb:Q74SA7	psi-mi:nell2_human(display_long)|uniprotkb:NELL2(gene name)|psi-mi:NELL2(display_short)|uniprotkb:NRP2(gene name synonym)|uniprotkb:NEL-like protein 2(gene name synonym)|uniprotkb:Nel-related protein 2(gene name synonym)	psi-mi:mdtb_yerpe(display_long)|uniprotkb:mdtB(gene name)|psi-mi:mdtB(display_short)|uniprotkb:Multidrug transporter MdtB(gene name synonym)|uniprotkb:YPO2848(locus name)|uniprotkb:y1385(locus name)|uniprotkb:YP_2715(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857595|imex:IM-13779-6223	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138579.1|refseq:NP_001138580.1|refseq:NP_001138581.1|refseq:NP_001138582.1|refseq:NP_006150.1|refseq:XP_005268962.1|refseq:XP_011536698.1|ensembl:ENSG00000184613.11(gene)|ensembl:ENST00000429094.7(transcript)|ensembl:ENST00000452445.6(transcript)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0008201""(heparin binding)|go:""GO:0009566""(fertilization)|go:""GO:0042802""(identical protein binding)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0071679""(commissural neuron axon guidance)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR024731|interpro:IPR048287|interpro:IPR049883|interpro:IPR051586|mint:Q99435|rcsb pdb:6POG|reactome:R-HSA-428542|dip:DIP-49927N|panther:PTHR24042(orthology-group)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR022831|interpro:IPR027463|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:WP_002209793.1|refseq:YP_002347786.1|panther:PTHR32063(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/NYlmX9iC3H17WXd+u97CVwOD7c9606	rogid:LHw1WKWrAW5/xlsQ5C6WVb5Ua3M632	intact-crc:A449D8C688BAB8B3|rigid:/C7LdKKYR5k5N5/c2qInWcus/v8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96LM7	uniprotkb:A0A2U2H0W0	intact:EBI-2796677|ensembl:ENSP00000375732.2	intact:EBI-2857561|uniprotkb:Q74U91|uniprotkb:Q0WFF6|uniprotkb:A0A380PDB4|uniprotkb:Q7CI92|uniprotkb:A0A384L848	psi-mi:q96lm7_human(display_long)|uniprotkb:CD37(gene name)|psi-mi:CD37(display_short)	psi-mi:a0a2u2h0w0_yerpe(display_long)|uniprotkb:YPO1997(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857566|imex:IM-13779-6222	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000104894.12(gene)|ensembl:ENST00000391859.6(transcript)|go:""GO:0016020""(membrane)|interpro:IPR018499|interpro:IPR018503"	interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR052750|interpro:IPR029058|refseq:WP_002211257.1|refseq:YP_002346982.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tcTp+2kI1f21WZWslX4/BwTVp549606	rogid:DP6LxF8YTJKUt3yW/2M2CRKvosU632	intact-crc:F0E09B263246EDFC|rigid:ObqR4K/baZRncMauagLyTGA7sik	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q53GL7	uniprotkb:A0A6B3V616	intact:EBI-2857573|uniprotkb:Q8N2I0|uniprotkb:Q8WV05|uniprotkb:Q96CH7|uniprotkb:Q96K72|ensembl:ENSP00000325618.7	intact:EBI-2857577|uniprotkb:Q74Q35|uniprotkb:A0A0H2W7S3|uniprotkb:Q0WJG3|uniprotkb:Q7CG93|uniprotkb:A0A384KHH0	psi-mi:par10_human(display_long)|uniprotkb:Poly [ADP-ribose] polymerase 10(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 10(gene name synonym)|uniprotkb:PARP10(gene name)|psi-mi:PARP10(display_short)	psi-mi:a0a6b3v616_yerpe(display_long)|uniprotkb:YPO0502(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857581|imex:IM-13779-6220	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_116178.2|ensembl:ENSG00000178685.14(gene)|ensembl:ENST00000313028.12(transcript)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0019082""(viral protein processing)|go:""GO:0019985""(translesion synthesis)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0034356""(obsolete NAD biosynthesis via nicotinamide riboside salvage pathway)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0070212""(protein poly-ADP-ribosylation)|go:""GO:0070213""(protein auto-ADP-ribosylation)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140804""(NAD+-protein-lysine ADP-ribosyltransferase activity)|go:""GO:0140806""(NAD+-protein-aspartate ADP-ribosyltransferase activity)|go:""GO:0140822""(NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity)|go:""GO:0140844""(NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity)|go:""GO:0140867""(NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity)|go:""GO:1900045""(negative regulation of protein K63-linked ubiquitination)|go:""GO:1990404""(NAD+-protein mono-ADP-ribosyltransferase activity)|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034464|interpro:IPR052056|mint:Q53GL7|rcsb pdb:2DHX|rcsb pdb:3HKV|rcsb pdb:5LX6|rcsb pdb:6FXI|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|panther:PTHR14453(orthology-group)"	interpro:IPR008514(Virulence factor for secretion apparatus)|interpro:IPR053165|refseq:WP_002210479.1|interpro:IPR036624|refseq:YP_002345575.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WcJRnNPrEAYD6vk9c4ACoh5fX1U9606	rogid:z1mUVhDpcORzcdxvl6Z6OeK/kFI632	intact-crc:2E4163D0BF01A831|rigid:wkfqxucHpfZ/M+cpmq3m6VVfVEc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99435	uniprotkb:A0A0H2W7X9	intact:EBI-946274|intact:EBI-2845314|uniprotkb:B7Z2U7|uniprotkb:B7Z5Q4|uniprotkb:B7Z9J5|uniprotkb:B7Z9U3|uniprotkb:Q96JS2|ensembl:ENSP00000390680.2|ensembl:ENSP00000394612.2	intact:EBI-2843015|uniprotkb:Q74QK1|uniprotkb:Q7CHN2|uniprotkb:Q0WI67|uniprotkb:Q7CGP9	psi-mi:nell2_human(display_long)|uniprotkb:NELL2(gene name)|psi-mi:NELL2(display_short)|uniprotkb:NRP2(gene name synonym)|uniprotkb:NEL-like protein 2(gene name synonym)|uniprotkb:Nel-related protein 2(gene name synonym)	psi-mi:a0a0h2w7x9_yerpe(display_long)|uniprotkb:ISU59_06840(orf name)|uniprotkb:YPO0974(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857588|imex:IM-13779-6221	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138579.1|refseq:NP_001138580.1|refseq:NP_001138581.1|refseq:NP_001138582.1|refseq:NP_006150.1|refseq:XP_005268962.1|refseq:XP_011536698.1|ensembl:ENSG00000184613.11(gene)|ensembl:ENST00000429094.7(transcript)|ensembl:ENST00000452445.6(transcript)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0008201""(heparin binding)|go:""GO:0009566""(fertilization)|go:""GO:0042802""(identical protein binding)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0071679""(commissural neuron axon guidance)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR024731|interpro:IPR048287|interpro:IPR049883|interpro:IPR051586|mint:Q99435|rcsb pdb:6POG|reactome:R-HSA-428542|dip:DIP-49927N|panther:PTHR24042(orthology-group)"	"interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|refseq:WP_002228049.1|go:""GO:0016020""(membrane)|interpro:IPR036737|refseq:YP_002346021.1|interpro:IPR050330|panther:PTHR30329(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/NYlmX9iC3H17WXd+u97CVwOD7c9606	rogid:Kx+QXBlmlUG6k9akoh2hB1wlo3I632	intact-crc:69C70288A2683C2A|rigid:1Bf2J0UE/eWjdRbJsl4WB/B0+Ug	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B0I1T2	uniprotkb:A0A5P8YB67	intact:EBI-2857637|uniprotkb:Q96RI5|uniprotkb:Q8TEI9|uniprotkb:Q96RI6|uniprotkb:Q8TES2|uniprotkb:Q96BE2|ensembl:ENSP00000258787.7	intact:EBI-2854189|uniprotkb:Q74R15|uniprotkb:Q0WAN8|uniprotkb:Q7CKU7|uniprotkb:A0A384K8J9	psi-mi:myo1g_human(display_long)|uniprotkb:MYO1G(gene name)|psi-mi:MYO1G(display_short)|uniprotkb:HA2(gene name synonym)	psi-mi:a0a5p8yb67_yerpe(display_long)|uniprotkb:hemB(gene name)|psi-mi:hemB(display_short)|uniprotkb:ncf(gene name synonym)|uniprotkb:YPO3771(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857647|imex:IM-13779-6226	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_149043.2|ensembl:ENSG00000136286.16(gene)|ensembl:ENST00000258787.12(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0006887""(exocytosis)|go:""GO:0006897""(endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016459""(myosin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030175""(filopodium)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0043325""(phosphatidylinositol-3,4-bisphosphate binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071976""(cell gliding)|go:""GO:0072678""(T cell migration)|go:""GO:0120117""(T cell meandering migration)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:B0I1T2|panther:PTHR13140(orthology-group)"	"interpro:IPR030656|interpro:IPR001731(Tetrapyrrole biosynthesis, porphobilinogen synthase)|interpro:IPR013785(Aldolase-type TIM barrel)|refseq:WP_002211541.1|go:""GO:0004655""(porphobilinogen synthase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0008270""(zinc ion binding)|refseq:YP_002348650.1|panther:PTHR11458(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9VsQfp7AsKTN+3jpHkAWsSbNoxc9606	rogid:XQVKiDYNUJHbMuNEDPkNJYaXWVU632	intact-crc:EA9389CE661E4B41|rigid:DLti32N2PNEe0DQEKQB82/7QrAg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WDK1	uniprotkb:Q96H41	intact:EBI-2850684|uniprotkb:Q74ST1|uniprotkb:A0A0H2W551|uniprotkb:A0A5P8YJE0|uniprotkb:Q7CJR5|uniprotkb:A0A384L7X2	intact:EBI-2857612	psi-mi:q0wdk1_yerpe(display_long)|uniprotkb:kdpD(gene name)|psi-mi:kdpD(display_short)|uniprotkb:YPO2689(locus name)	psi-mi:q96h41_human(display_long)|uniprotkb:SETMAR(gene name)|psi-mi:SETMAR(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857609|imex:IM-13779-6224	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR027417|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003852(Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal)|interpro:IPR029016|interpro:IPR025201|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016020""(membrane)|interpro:IPR038318|interpro:IPR036097|interpro:IPR036890|refseq:WP_002209649.1|refseq:YP_002347637.1|interpro:IPR052023"	"refseq:NP_001307605.1|interpro:IPR036397|interpro:IPR001888(Transposase, type 1)|interpro:IPR052709|go:""GO:0003676""(nucleic acid binding)|interpro:IPR036388|interpro:IPR041426"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Fbp8vVsab8EtVWWrBsbzda/Mi7I632	rogid:AfDtKaikeHt4BOCLUSuvqJcWTYY9606	intact-crc:DC666C152459D31E|rigid:rpSYrKb2Hyep6vS5vjF23/0AwLo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YAL1	uniprotkb:Q96I30	intact:EBI-2847693|uniprotkb:Q74QT5|uniprotkb:A0A0H2W741|uniprotkb:Q7CFS1|uniprotkb:A0A384LBQ5	intact:EBI-721013	psi-mi:a0a5p8yal1_yerpe(display_long)|uniprotkb:yhjW(gene name)|psi-mi:yhjW(display_short)|uniprotkb:YPO4013(locus name)	psi-mi:q96i30_human(display_long)|uniprotkb:GPR108(gene name)|psi-mi:GPR108(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857602|imex:IM-13779-6228	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR012549(Protein of unknown function DUF1705)|interpro:IPR000917(Sulphatase)|refseq:WP_002209571.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009244""(lipopolysaccharide core region biosynthetic process)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0043838""(""phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity"")|interpro:IPR040423|refseq:YP_002348879.1|panther:PTHR30443(orthology-group)"	"interpro:IPR009637(Transmembrane receptor, eukaryota)|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HkeTpMUkl5+g00S4VZSWIDHQ28c632	rogid:NWZX6zLdtUNdp/DDz0ZXm75ra/c9606	intact-crc:5289691A5C52518A|rigid:GsSdyGr/kgijnARdIoplKP3bLMM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W0I2	uniprotkb:Q6UXT9	intact:EBI-2847735|uniprotkb:Q74XP3|uniprotkb:Q0WBW4|uniprotkb:Q7CKA9|uniprotkb:A0A384L3M8	intact:EBI-2824666|uniprotkb:Q96EC5|ensembl:ENSP00000302657.3	psi-mi:a0a0h2w0i2_yerpe(display_long)|uniprotkb:YPO3328(locus name)	psi-mi:abh15_human(display_long)|uniprotkb:ABHD15(gene name)|psi-mi:ABHD15(display_short)|uniprotkb:Alpha/beta hydrolase domain-containing protein 15(gene name synonym)|uniprotkb:UNQ6510/PRO21435(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857630|imex:IM-13779-6225	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025997|interpro:IPR028082|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002348224.1|interpro:IPR050555"	"refseq:NP_937790.2|ensembl:ENSG00000168792.5(gene)|ensembl:ENST00000307201.5(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0034338""(short-chain carboxylesterase activity)|go:""GO:0047372""(monoacylglycerol lipase activity)|go:""GO:0060612""(adipose tissue development)|interpro:IPR029058|interpro:IPR050960|panther:PTHR10794(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HHGoonb2nUNXAajQaaTnNuqKf7g632	rogid:wcKuX4uLcT3HXmm2mKi6qbH5nrU9606	intact-crc:87D674B96CC5185B|rigid:41eLquLkX9sYvZFhI5iXzLlN4fI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WKD7	uniprotkb:Q96FB2	intact:EBI-2842097|uniprotkb:Q74Y17|uniprotkb:Q7CFV7|uniprotkb:A0A380PIN1|uniprotkb:A0A0H2W080	intact:EBI-2857623	psi-mi:q0wkd7_yerpe(display_long)|uniprotkb:YPO0165(locus name)	psi-mi:q96fb2_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857620|imex:IM-13779-6227	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000843(Bacterial regulatory protein, LacI)|interpro:IPR028082|go:""GO:0003677""(DNA binding)|go:""GO:0006355""(regulation of DNA-templated transcription)|refseq:WP_002208881.1|refseq:YP_002345251.1|interpro:IPR046335"	"refseq:NP_001523.2|interpro:IPR002259(Delayed-early response protein/equilibrative nucleoside transporter)|refseq:NP_001287798.1|go:""GO:0005337""(nucleoside transmembrane transporter activity)|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:djLG9eflkpuHq1g4QCFSjvuK4eI632	rogid:lE2bYeysiEHB50gsB3C7RalKWp09606	intact-crc:441D3F3E0C873ADD|rigid:VWb6I/RjuQIeTrp/IILS0q8jL+E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q95HL4	uniprotkb:Q8D087	intact:EBI-2857695	intact:EBI-2857699	psi-mi:q95hl4_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)	psi-mi:q8d087_yerpe(display_long)|uniprotkb:y2582(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857692|imex:IM-13779-6230	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR050160|go:""GO:0006955""(immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0042613""(MHC class II protein complex)"	"interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR002252(Glycoside hydrolase, family 36)|interpro:IPR000111(Glycoside hydrolase, clan GH-D)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031704|interpro:IPR050985|go:""GO:0004557""(alpha-galactosidase activity)|go:""GO:0016052""(carbohydrate catabolic process)|interpro:IPR038417"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Q8XwQHuG3NNlN/KC5qspCuNWal49606	rogid:TX42uijKrKJOqqTMDU9cwszICWU632	intact-crc:3D7550C3A615ADE0|rigid:jd/ut1MAQwz92I+y7iYr+J4FRWU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96HM7	uniprotkb:Q8Z9R8	intact:EBI-1222622|intact:EBI-2857661|uniprotkb:Q96B20|ensembl:ENSP00000396040.1|ensembl:ENSP00000446688.1	intact:EBI-2839934|uniprotkb:Q0W9Q7|intact:EBI-2857683|intact:EBI-2870000	psi-mi:ped1b_human(display_long)|uniprotkb:FAM113B(gene name synonym)|uniprotkb:Protein FAM113B(gene name synonym)|uniprotkb:PCED1B(gene name)|psi-mi:PCED1B(display_short)	psi-mi:mnmg_yerpe(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:YPO4130(locus name)|uniprotkb:y4144(locus name)|uniprotkb:YP_4037(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857680|imex:IM-13779-6232	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001268358.1|refseq:NP_612380.1|refseq:XP_005269281.1|refseq:XP_011537280.1|refseq:XP_016875696.1|refseq:XP_016875697.1|refseq:XP_016875698.1|refseq:XP_016875699.1|refseq:XP_016875700.1|refseq:XP_016875701.1|refseq:XP_016875702.1|refseq:XP_016875703.1|refseq:XP_016875704.1|refseq:XP_016875705.1|ensembl:ENSG00000179715.13(gene)|ensembl:ENST00000432328.2(transcript)|ensembl:ENST00000546455.6(transcript)|interpro:IPR036514|panther:PTHR14469(orthology-group)	"interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|interpro:IPR044920|interpro:IPR026904|refseq:WP_002212259.1|interpro:IPR049312|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|interpro:IPR047001|refseq:YP_002348981.1|interpro:IPR040131|panther:PTHR11806(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zdnRSKAuaixZ1c9X1oerWNI9A9c9606	rogid:v90IkqKm+dlosxfAPKVYWCflBG4632	intact-crc:0FDB15FB94BF7F17|rigid:y3S7QrS+E/geT1jDEFf+0iBzqlY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YHJ0	uniprotkb:B0I1T2	intact:EBI-2840822|uniprotkb:A0A384KBR7|uniprotkb:Q0WCM8|uniprotkb:Q7CJI0	intact:EBI-2857637|uniprotkb:Q96RI5|uniprotkb:Q8TEI9|uniprotkb:Q96RI6|uniprotkb:Q8TES2|uniprotkb:Q96BE2|ensembl:ENSP00000258787.7	psi-mi:a0a5p8yhj0_yerpe(display_long)|uniprotkb:napF(gene name)|psi-mi:napF(display_short)|uniprotkb:YPO3040(locus name)	psi-mi:myo1g_human(display_long)|uniprotkb:MYO1G(gene name)|psi-mi:MYO1G(display_short)|uniprotkb:HA2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857654|imex:IM-13779-6229	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR004496(Ferredoxin-type protein NapF)|refseq:YP_002347960.1|interpro:IPR017900|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002208536.1|interpro:IPR050572|panther:PTHR24960(orthology-group)"	"refseq:NP_149043.2|ensembl:ENSG00000136286.16(gene)|ensembl:ENST00000258787.12(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0006887""(exocytosis)|go:""GO:0006897""(endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016459""(myosin complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030175""(filopodium)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0043325""(phosphatidylinositol-3,4-bisphosphate binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071976""(cell gliding)|go:""GO:0072678""(T cell migration)|go:""GO:0120117""(T cell meandering migration)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:B0I1T2|panther:PTHR13140(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eff9jqgNqHt/SEUvObWFEj5j/tU632	rogid:9VsQfp7AsKTN+3jpHkAWsSbNoxc9606	intact-crc:670E6D0D4B106993|rigid:+r/mneLSFNySzSmwh2WbX1nRHxk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96HM7	uniprotkb:Q8ZE20	intact:EBI-1222622|intact:EBI-2857661|uniprotkb:Q96B20|ensembl:ENSP00000396040.1|ensembl:ENSP00000446688.1	intact:EBI-2857666|uniprotkb:Q74TK0|uniprotkb:Q0WEF3|uniprotkb:Q8D0L4	psi-mi:ped1b_human(display_long)|uniprotkb:FAM113B(gene name synonym)|uniprotkb:Protein FAM113B(gene name synonym)|uniprotkb:PCED1B(gene name)|psi-mi:PCED1B(display_short)	psi-mi:syy_yerpe(display_long)|uniprotkb:tyrS(gene name)|psi-mi:tyrS(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO2369(locus name)|uniprotkb:YP_2155(locus name)|uniprotkb:y1966(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857673|imex:IM-13779-6231	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001268358.1|refseq:NP_612380.1|refseq:XP_005269281.1|refseq:XP_011537280.1|refseq:XP_016875696.1|refseq:XP_016875697.1|refseq:XP_016875698.1|refseq:XP_016875699.1|refseq:XP_016875700.1|refseq:XP_016875701.1|refseq:XP_016875702.1|refseq:XP_016875703.1|refseq:XP_016875704.1|refseq:XP_016875705.1|ensembl:ENSG00000179715.13(gene)|ensembl:ENST00000432328.2(transcript)|ensembl:ENST00000546455.6(transcript)|interpro:IPR036514|panther:PTHR14469(orthology-group)	"interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002942(RNA-binding S4)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR024088|interpro:IPR024107|refseq:WP_002210960.1|go:""GO:0003723""(RNA binding)|go:""GO:0004831""(tyrosine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006437""(tyrosyl-tRNA aminoacylation)|go:""GO:0043039""(tRNA aminoacylation)|interpro:IPR054608|interpro:IPR036986|refseq:YP_002347335.1|panther:PTHR11766(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zdnRSKAuaixZ1c9X1oerWNI9A9c9606	rogid:BUagKLSbiLvLgJHoonFfm7nI4ss632	intact-crc:948E09FB964FAA66|rigid:LET8s6OTzhFqEeJck8qTAdEZQ+0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92827	uniprotkb:Q8CLV1	intact:EBI-2845336	intact:EBI-2856975	psi-mi:q92827_human(display_long)|uniprotkb:MYO1F(gene name)|psi-mi:MYO1F(display_short)	psi-mi:q8clv1_yerpe(display_long)|uniprotkb:gabD_2(gene name)|psi-mi:gabD_2(display_short)|uniprotkb:NCTC5923_00696(orf name)|uniprotkb:y0175(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857717|imex:IM-13779-6236	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001609(Myosin head, motor region)|interpro:IPR027417|go:""GO:0000146""(microfilament motor activity)|go:""GO:0003779""(actin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0016461""(unconventional myosin complex)|interpro:IPR036961"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR050740|go:""GO:0036243""(""succinate-semialdehyde dehydrogenase (NADP+) activity"")|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sYVVJef8ak9YNyN/GxbJcqHg4ok9606	rogid:6zYk/wgwNbJp4HA15TbUfK5jmJs632	intact-crc:F15D4FA3987FA94C|rigid:cCP/4S6BsVq7cZaXyGXih1A2FAw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92982	uniprotkb:Q8D0C8	intact:EBI-2802124|uniprotkb:Q6GU89|uniprotkb:Q9BT07|uniprotkb:Q8WUV5|ensembl:ENSP00000364595.4	intact:EBI-2845934|uniprotkb:Q74UN2	psi-mi:ninj1_human(display_long)|uniprotkb:Nerve injury-induced protein 1(gene name synonym)|uniprotkb:NINJ1(gene name)|psi-mi:NINJ1(display_short)	psi-mi:q8d0c8_yerpe(display_long)|uniprotkb:aRO81(gene name)|psi-mi:aRO81(display_short)|uniprotkb:YP_1678(locus name)|uniprotkb:y2375(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857738|imex:IM-13779-6237	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004139.2|ensembl:ENSG00000131669.10(gene)|ensembl:ENST00000375446.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002232""(leukocyte chemotaxis involved in inflammatory response)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007399""(nervous system development)|go:""GO:0019835""(cytolysis)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0071474""(cellular hyperosmotic response)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097707""(ferroptosis)|go:""GO:0098631""(cell adhesion mediator activity)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:0141201""(pyroptotic cell death)|interpro:IPR007007(Ninjurin)|rcsb pdb:8CQR|rcsb pdb:8SZA|rcsb pdb:8UIP|panther:PTHR12316(orthology-group)"	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR050859"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wepu2O1BvKU/BGYreACextfDAdk9606	rogid:r71UI6xxi/cqjPI/E/qSei9l3XY632	intact-crc:7CE533DB0E5C495F|rigid:UapGsy80aVhh62lLJWUyXFuv5Fs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H2N4	uniprotkb:Q92942	intact:EBI-2857706|uniprotkb:Q74SJ9|uniprotkb:Q0WCT8|uniprotkb:Q7CJE8|uniprotkb:A0A384LL35	intact:EBI-1760273	psi-mi:a0a2u2h2n4_yerpe(display_long)|uniprotkb:YPO2976(locus name)	psi-mi:q92942_human(display_long)|uniprotkb:RGL2(gene name)|psi-mi:RGL2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857710|imex:IM-13779-6233	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010856(Protein of unknown function DUF1479)|interpro:IPR027443|rcsb pdb:7TWC|rcsb pdb:7TWE|rcsb pdb:4RGK|refseq:WP_002211614.1|go:""GO:0046872""(metal ion binding)|refseq:YP_002347900.1|panther:PTHR30613(orthology-group)"	"interpro:IPR000159(Ras-association)|interpro:IPR019804|interpro:IPR023578|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR029071|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR036964|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0035556""(intracellular signal transduction)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5BmDBtq/2vImcXeb2aVJBfZU0M4632	rogid:YSGPD8lMR2qcO755GePCur/dwK09606	intact-crc:138481CB38E8F240|rigid:gLOaDKPc1XB8mkpYRW7H4IGbhfg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ02	uniprotkb:Q92982	intact:EBI-2855503|uniprotkb:Q0WJX8|uniprotkb:Q7CKN8|uniprotkb:Q74XE7	intact:EBI-2802124|uniprotkb:Q6GU89|uniprotkb:Q9BT07|uniprotkb:Q8WUV5|ensembl:ENSP00000364595.4	"psi-mi:rhab_yerpe(display_long)|uniprotkb:rhaB(gene name)|psi-mi:rhaB(display_short)|uniprotkb:Rhamnulose kinase(gene name synonym)|uniprotkb:YPO0330(locus name)|uniprotkb:y0587(locus name)|uniprotkb:YP_0485(locus name)|uniprotkb:L-rhamnulose 1-kinase(gene name synonym)|uniprotkb:""ATP:L-rhamnulose phosphotransferase""(gene name synonym)"	psi-mi:ninj1_human(display_long)|uniprotkb:Nerve injury-induced protein 1(gene name synonym)|uniprotkb:NINJ1(gene name)|psi-mi:NINJ1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857731|imex:IM-13779-6235	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018485|interpro:IPR018484|interpro:IPR013449(Rhamnulokinase)|interpro:IPR000577(Carbohydrate kinase, FGGY)|refseq:WP_002209105.1|go:""GO:0004370""(glycerol kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008993""(rhamnulokinase activity)|go:""GO:0019301""(rhamnose catabolic process)|interpro:IPR043129|refseq:YP_002345410.1|panther:PTHR10196(orthology-group)"	"refseq:NP_004139.2|ensembl:ENSG00000131669.10(gene)|ensembl:ENST00000375446.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002232""(leukocyte chemotaxis involved in inflammatory response)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007399""(nervous system development)|go:""GO:0019835""(cytolysis)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0071474""(cellular hyperosmotic response)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097707""(ferroptosis)|go:""GO:0098631""(cell adhesion mediator activity)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:0141201""(pyroptotic cell death)|interpro:IPR007007(Ninjurin)|rcsb pdb:8CQR|rcsb pdb:8SZA|rcsb pdb:8UIP|panther:PTHR12316(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lL9J4K2xcNV9zW+r3/RgTvxRYeQ632	rogid:wepu2O1BvKU/BGYreACextfDAdk9606	intact-crc:F695FA650C1049E6|rigid:yVjY/LTV/BrU5rJTAmws4vKoJME	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WY97	uniprotkb:Q8D1P4	intact:EBI-2824704	intact:EBI-2845144	psi-mi:q8wy97_human(display_long)	psi-mi:q8d1p4_yerpe(display_long)|uniprotkb:y0195(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857724|imex:IM-13779-6234	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	interpro:IPR032712|interpro:IPR025263|interpro:IPR011836(Conserved hypothetical protein CHP02099)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:A8otEVwzTdMo+G4wobntjuykjqw9606	rogid:k1ALZgWrTdqeyJ1mZBZgusKWD8Y632	intact-crc:76E09617478D0679|rigid:GWM9h2p6mFsHrPHIwDDco9s7TFQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z5L9	uniprotkb:Q7CGT3	intact:EBI-2857769|ensembl:ENSP00000355568.3|uniprotkb:B1AM36|uniprotkb:Q7Z5L8|uniprotkb:Q6P083|uniprotkb:Q8N351|uniprotkb:B1AM35|uniprotkb:Q8WUH8	intact:EBI-2851362|uniprotkb:Q74Q94	psi-mi:i2bp2_human(display_long)|uniprotkb:IRF2BP2(gene name)|psi-mi:IRF2BP2(display_short)	psi-mi:ygfz_yerpe(display_long)|uniprotkb:YPO0898(locus name)|uniprotkb:y3283(locus name)|uniprotkb:YP_3595(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857766|imex:IM-13779-6241	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1572""|efo:""Orphanet:520""|ensembl:ENSG00000168264.12(gene)|ensembl:ENST00000366609.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002327""(immature B cell differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR022750|interpro:IPR044882|mint:Q7Z5L9|refseq:NP_001070865.1|refseq:NP_892017.2|panther:PTHR10816(orthology-group)"	"interpro:IPR029043|interpro:IPR023758|interpro:IPR017703(Folate-binding, YgfZ)|refseq:WP_002209940.1|go:""GO:0005542""(folic acid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008033""(tRNA processing)|go:""GO:0009451""(RNA modification)|go:""GO:0016226""(iron-sulfur cluster assembly)|interpro:IPR048451|refseq:YP_002345947.1|interpro:IPR045179|panther:PTHR22602(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:D7vDkesEqSEgGURqQ0LM7XhXdRk9606	rogid:qsp6c7iyJPkACUpbuAv36AvJDYs632	intact-crc:502F18D8CD403250|rigid:hWRHXxYL1CmIqkwyrmR3gEFnbbc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92982	uniprotkb:A0A5P8YHJ0	intact:EBI-2802124|uniprotkb:Q6GU89|uniprotkb:Q9BT07|uniprotkb:Q8WUV5|ensembl:ENSP00000364595.4	intact:EBI-2840822|uniprotkb:A0A384KBR7|uniprotkb:Q0WCM8|uniprotkb:Q7CJI0	psi-mi:ninj1_human(display_long)|uniprotkb:Nerve injury-induced protein 1(gene name synonym)|uniprotkb:NINJ1(gene name)|psi-mi:NINJ1(display_short)	psi-mi:a0a5p8yhj0_yerpe(display_long)|uniprotkb:napF(gene name)|psi-mi:napF(display_short)|uniprotkb:YPO3040(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857759|imex:IM-13779-6239	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004139.2|ensembl:ENSG00000131669.10(gene)|ensembl:ENST00000375446.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002232""(leukocyte chemotaxis involved in inflammatory response)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007399""(nervous system development)|go:""GO:0019835""(cytolysis)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0071474""(cellular hyperosmotic response)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097707""(ferroptosis)|go:""GO:0098631""(cell adhesion mediator activity)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:0141201""(pyroptotic cell death)|interpro:IPR007007(Ninjurin)|rcsb pdb:8CQR|rcsb pdb:8SZA|rcsb pdb:8UIP|panther:PTHR12316(orthology-group)"	"interpro:IPR017896|interpro:IPR004496(Ferredoxin-type protein NapF)|refseq:YP_002347960.1|interpro:IPR017900|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002208536.1|interpro:IPR050572|panther:PTHR24960(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wepu2O1BvKU/BGYreACextfDAdk9606	rogid:eff9jqgNqHt/SEUvObWFEj5j/tU632	intact-crc:3421733E4C9D5FBF|rigid:nOxrzD9PsZDwy5k4RnEOL5/pE94	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H1T2	uniprotkb:Q92982	intact:EBI-2847930|uniprotkb:A0A380PGD9|uniprotkb:Q0WBW0|uniprotkb:Q7CKB2|uniprotkb:A0A384KAJ5	intact:EBI-2802124|uniprotkb:Q6GU89|uniprotkb:Q9BT07|uniprotkb:Q8WUV5|ensembl:ENSP00000364595.4	psi-mi:a0a2u2h1t2_yerpe(display_long)|uniprotkb:YPO3332(locus name)	psi-mi:ninj1_human(display_long)|uniprotkb:Nerve injury-induced protein 1(gene name synonym)|uniprotkb:NINJ1(gene name)|psi-mi:NINJ1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857745|imex:IM-13779-6240	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|refseq:WP_002216010.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:YP_002348228.1"	"refseq:NP_004139.2|ensembl:ENSG00000131669.10(gene)|ensembl:ENST00000375446.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002232""(leukocyte chemotaxis involved in inflammatory response)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007399""(nervous system development)|go:""GO:0019835""(cytolysis)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0071474""(cellular hyperosmotic response)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097707""(ferroptosis)|go:""GO:0098631""(cell adhesion mediator activity)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:0141201""(pyroptotic cell death)|interpro:IPR007007(Ninjurin)|rcsb pdb:8CQR|rcsb pdb:8SZA|rcsb pdb:8UIP|panther:PTHR12316(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pJcJoiSi0mBqBQjt8m5FB8UHoDE632	rogid:wepu2O1BvKU/BGYreACextfDAdk9606	intact-crc:E6BC48DF39AB6E77|rigid:MejNhTGS4CBqQkcIv2hRiwego5U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GWQ4	uniprotkb:Q92982	intact:EBI-2845580|uniprotkb:Q74SR7|uniprotkb:Q0WDH9|uniprotkb:Q7CJQ8|uniprotkb:A0A380PMW3|uniprotkb:A0A384L966	intact:EBI-2802124|uniprotkb:Q6GU89|uniprotkb:Q9BT07|uniprotkb:Q8WUV5|ensembl:ENSP00000364595.4	psi-mi:a0a2u2gwq4_yerpe(display_long)|uniprotkb:mclA(gene name)|psi-mi:mclA(display_short)|uniprotkb:Regulator of SigE(gene name synonym)|uniprotkb:Sigma-E anti-sigma factor RseA(gene name synonym)|uniprotkb:Sigma-E factor negative regulatory protein(gene name synonym)|uniprotkb:rseA(gene name synonym)|uniprotkb:YPO2712(locus name)	psi-mi:ninj1_human(display_long)|uniprotkb:Nerve injury-induced protein 1(gene name synonym)|uniprotkb:NINJ1(gene name)|psi-mi:NINJ1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857752|imex:IM-13779-6238	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026279|interpro:IPR005573(Anti sigma-E protein RseA, C-terminal)|interpro:IPR005572(Anti sigma-E protein RseA, N-terminal)|go:""GO:0005886""(plasma membrane)|go:""GO:0016989""(sigma factor antagonist activity)|refseq:WP_002209673.1|interpro:IPR036147|refseq:YP_002347659.1|interpro:IPR052383"	"refseq:NP_004139.2|ensembl:ENSG00000131669.10(gene)|ensembl:ENST00000375446.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002232""(leukocyte chemotaxis involved in inflammatory response)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007399""(nervous system development)|go:""GO:0019835""(cytolysis)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0071474""(cellular hyperosmotic response)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097300""(programmed necrotic cell death)|go:""GO:0097707""(ferroptosis)|go:""GO:0098631""(cell adhesion mediator activity)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:0141201""(pyroptotic cell death)|interpro:IPR007007(Ninjurin)|rcsb pdb:8CQR|rcsb pdb:8SZA|rcsb pdb:8UIP|panther:PTHR12316(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LwZJGFoSTyhBT8PD/0j5gaZwEWc632	rogid:wepu2O1BvKU/BGYreACextfDAdk9606	intact-crc:7E66E32302A3CC78|rigid:ck7FfIPoE4Gcspg4cgMbUl4fRbI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6M0NII6	uniprotkb:Q8NF67	intact:EBI-2841704	intact:EBI-2339795	psi-mi:a0a6m0nii6_yerpe(display_long)|uniprotkb:y2471(locus name)	psi-mi:a2012_human(display_long)|uniprotkb:ANKRD20A12P(gene name)|psi-mi:ANKRD20A12P(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857839|imex:IM-13779-6244	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T0M9(uniprot-removed-ac)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR029016|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|refseq:WP_002228541.1"	interpro:IPR050657|interpro:IPR039497	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:d/mBSOpThH3MO4/Ze3GAgpPOK+o632	rogid:pbkYxUq9I5R4Fbswp3UxLD/wwOg9606	intact-crc:21ABF63E146B177D|rigid:XLnVCt004tuy3A8TJ0RJp5L6eb8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TDM2	uniprotkb:A0A5P8YFD8	intact:EBI-2857794	intact:EBI-2844797|uniprotkb:Q74TW8|uniprotkb:A0A0H2W658|uniprotkb:Q7CIM3|uniprotkb:A0A384L807	psi-mi:q8tdm2_human(display_long)|uniprotkb:HCBP1(gene name)|psi-mi:HCBP1(display_short)	psi-mi:a0a5p8yfd8_yerpe(display_long)|uniprotkb:trpE(gene name)|psi-mi:trpE(display_short)|uniprotkb:YPO2208(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857798|imex:IM-13779-6242	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016708(Aspartoacylase)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR050178|go:""GO:0005737""(cytoplasm)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016788""(hydrolase activity, acting on ester bonds)|go:""GO:0016811""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"")|go:""GO:0046872""(metal ion binding)"	"interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR019999|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR005257(Anthranilate synthase component I, TrpE)|interpro:IPR015890(Chorismate binding, C-terminal)|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004049""(anthranilate synthase activity)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347179.1|panther:PTHR11236(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2/Pr/Wp+bqzO73mv1KYB8i99Baw9606	rogid:4yY3KOTpkixAVvXxxbToZJUfRYM632	intact-crc:B20B96D621F12204|rigid:yaCc0MDpXGGt1xu4xco+uXFvdPU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCT9	uniprotkb:Q8TEE7	intact:EBI-2844687|uniprotkb:Q0WD28	intact:EBI-2857783	psi-mi:der_yerpe(display_long)|uniprotkb:der(gene name)|psi-mi:der(display_short)|uniprotkb:engA(gene name synonym)|uniprotkb:GTP-binding protein EngA(gene name synonym)|uniprotkb:YPO2875(locus name)|uniprotkb:y1357(locus name)|uniprotkb:YP_2741(locus name)	psi-mi:q8tee7_human(display_long)|uniprotkb:FLJ00250(gene name)|psi-mi:FLJ00250(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857787|imex:IM-13779-6246	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR032859|interpro:IPR016484(GTP-binding, EngA)|interpro:IPR006073(GTP1/OBG)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR031166|go:""GO:0005525""(GTP binding)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0043022""(ribosome binding)|refseq:WP_002209813.1|refseq:YP_002347810.1|panther:PTHR43834(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:a3YV0SOJTAdEtPWBkgeX/kJ6UR8632	rogid:ybAN1i/nfXYs37ojqaKImt7vZzc9606	intact-crc:E724AE53CC5C0D1F|rigid:IDG6ZaB8uQ2vkpZMZZDLWsElHac	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0H6	uniprotkb:Q8NG08	intact:EBI-2857816|uniprotkb:Q74TR8	intact:EBI-2857808|uniprotkb:Q4G0T2|uniprotkb:Q9H7L5|uniprotkb:A8K4C9|ensembl:ENSP00000247815.5|ensembl:ENSP00000443287.1	psi-mi:q8d0h6_yerpe(display_long)|uniprotkb:YP_2076(locus name)|uniprotkb:y2122(locus name)	psi-mi:helb_human(display_long)|uniprotkb:HELB(gene name)|psi-mi:HELB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857805|imex:IM-13779-6245	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR009216(Predicted virulence protein SrfB)	"refseq:NP_387467.2|refseq:XP_005269291.1|ensembl:ENSG00000127311.10(gene)|ensembl:ENST00000247815.9(transcript)|ensembl:ENST00000545134.1(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006269""(DNA replication, synthesis of primer)|go:""GO:0006281""(DNA repair)|go:""GO:0006974""(DNA damage response)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016604""(nuclear body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017116""(single-stranded DNA helicase activity)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0043139""(5'-3' DNA helicase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1903775""(regulation of DNA double-strand break processing)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR027417|interpro:IPR050534|mint:Q8NG08|rcsb pdb:7XV1|panther:PTHR43788(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MtJczcVzgkPo2FuN1Uy2RPZ0F3M632	rogid:raNaHGVcm41zMDqtYrqtYIDj1l49606	intact-crc:F3D7CDEBAC515027|rigid:pPRHO4ThfKctna2IVk/pZqzqTS4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NFI3	uniprotkb:Q8ZGK8	intact:EBI-2857825|uniprotkb:Q8TB86|uniprotkb:Q9H6U4|uniprotkb:Q659F0|ensembl:ENSP00000462333.1	intact:EBI-2840206|uniprotkb:Q0WHC9	psi-mi:enase_human(display_long)|uniprotkb:ENGASE(gene name)|psi-mi:ENGASE(display_short)	psi-mi:uxua_yerpe(display_long)|uniprotkb:uxuA(gene name)|psi-mi:uxuA(display_short)|uniprotkb:D-mannonate hydro-lyase(gene name synonym)|uniprotkb:YPO1283(locus name)|uniprotkb:YP_1308(locus name)|uniprotkb:y2902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857832|imex:IM-13779-6243	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001036038.1|ensembl:ENSG00000167280.17(gene)|ensembl:ENST00000579016.6(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006491""(N-glycan processing)|go:""GO:0033925""(mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity)|interpro:IPR001357(BRCT)|interpro:IPR005201(Glycoside hydrolase, family 85)|interpro:IPR032979|reactome:R-HSA-532668|panther:PTHR13246(orthology-group)"	"interpro:IPR004628(Mannonate dehydratase)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008927""(mannonate dehydratase activity)|go:""GO:0030145""(manganese ion binding)|go:""GO:0042840""(D-glucuronate catabolic process)|refseq:WP_002208813.1|refseq:YP_002346309.1|interpro:IPR036237|panther:PTHR30387(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TA6ob5I/6q81VxQRkTxzI3SA7kk9606	rogid:JhdXu0NB4lbIj/rl4GvHVR+RwwE632	intact-crc:82B63C287EE9C4CB|rigid:AMou1ywyTtrEhcLFJBvLdwL0KHc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q4LDE5	uniprotkb:A0A2S9PFM0	intact:EBI-2798103|ensembl:ENSP00000363593.2|uniprotkb:Q96JU7|uniprotkb:Q5VTE5|uniprotkb:Q5D213|uniprotkb:Q0P675|uniprotkb:Q9H284|uniprotkb:Q5T938|uniprotkb:Q9H8J9|uniprotkb:Q5VTE4|uniprotkb:Q7Z3G3|uniprotkb:Q7Z387|uniprotkb:Q8NBT9	intact:EBI-2846871|uniprotkb:Q74QH1|uniprotkb:A0A0H2W7H4|uniprotkb:Q7CGR9|uniprotkb:A0A384LFS9	psi-mi:svep1_human(display_long)|uniprotkb:C9orf13(gene name synonym)|uniprotkb:CCP22(gene name synonym)|uniprotkb:SELOB(gene name synonym)|uniprotkb:CCP module-containing protein 22(gene name synonym)|uniprotkb:Polydom(gene name synonym)|uniprotkb:Selectin-like osteoblast-derived protein(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-38(gene name synonym)|uniprotkb:SVEP1(gene name)|psi-mi:SVEP1(display_short)	psi-mi:a0a2s9pfm0_yerpe(display_long)|uniprotkb:YPO0938(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857882|imex:IM-13779-6250	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165124.19(gene)|ensembl:ENST00000374469.6(transcript)|go:""GO:0003017""(lymph circulation)|go:""GO:0003682""(chromatin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008544""(epidermis development)|go:""GO:0010467""(gene expression)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0016020""(membrane)|go:""GO:0036303""(lymph vessel morphogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0048014""(Tie signaling pathway)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0120193""(tight junction organization)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001759(Pentaxin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003410(Hyalin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011641(GCC2 and GCC3)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR035976|interpro:IPR036465|interpro:IPR049883|interpro:IPR050350|mint:Q4LDE5|refseq:NP_699197.3|panther:PTHR19325(orthology-group)"	"interpro:IPR017755(N-carbamoylputrescine amidase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:WP_002209979.1|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0050126""(N-carbamoylputrescine amidase activity)|interpro:IPR036526|refseq:YP_002345985.1|interpro:IPR050345"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Eql8u2cebsRMv79rjBrmS/0b9Ec9606	rogid:VEt5ZICBEzJqD2dQaZCgWKgplSI632	intact-crc:9570FF3F9C0892EC|rigid:9Fh2Q5vuvLua6TwwNtQI9regtvg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2857896	uniprotkb:O68723	-	intact:EBI-2857889|uniprotkb:Q74YR2	psi-mi:q8nbk5_human(display_short)|psi-mi:EBI-2857896(display_long)	psi-mi:o68723_yerpe(display_long)|uniprotkb:Y1050(locus name)|uniprotkb:YP_pMT006(locus name)|uniprotkb:ORF90(gene name)|psi-mi:ORF90(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857893|imex:IM-13779-6248	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q8NBK5(uniprot-removed-ac)	interpro:IPR025484	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:OZFkxl3As03E0sa5pPXdevNZfhM632	intact-crc:CAF86475A5C036B4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PJT7	uniprotkb:A0A2U2H2H7	intact:EBI-740660|uniprotkb:B4DXU8|uniprotkb:B4DZW7|uniprotkb:A8MY46|uniprotkb:Q6MZU4|uniprotkb:Q6PJ32|uniprotkb:Q6PUI6|uniprotkb:Q6PUI8|uniprotkb:Q86TQ5|uniprotkb:Q86TW0|uniprotkb:Q86TW1|uniprotkb:Q8NCZ3|uniprotkb:Q8TDE2|uniprotkb:Q9HAC9|uniprotkb:Q9Y5A0|uniprotkb:Q8NCT6|intact:EBI-2857849|uniprotkb:B4E2H4|uniprotkb:G3V5R4|ensembl:ENSP00000251038.5	intact:EBI-2853632|uniprotkb:Q74PQ7|uniprotkb:A0A0H2W8Q9|uniprotkb:A0A380PH97|uniprotkb:Q7CL87|uniprotkb:A0A384KJ22	psi-mi:zc3he_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-37(gene name synonym)|uniprotkb:ZC3H14(gene name)|psi-mi:ZC3H14(display_short)|uniprotkb:Mammalian suppressor of tau pathology-2(gene name synonym)	psi-mi:a0a2u2h2h7_yerpe(display_long)|uniprotkb:yrbK(gene name)|psi-mi:yrbK(display_short)|uniprotkb:lptC(gene name synonym)|uniprotkb:YPO3579(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857846|imex:IM-13779-6247	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100722.20(gene)|ensembl:ENST00000251038.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0016607""(nuclear speck)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0046872""(metal ion binding)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR040366|refseq:NP_001153575.1|refseq:NP_001153576.1|refseq:NP_001313236.1|refseq:NP_079100.2|refseq:NP_997543.1|refseq:NP_997544.1|refseq:NP_997545.2|refseq:XP_005268125.1|efo:""Orphanet:88616""|panther:PTHR14738(orthology-group)"	"interpro:IPR052363|interpro:IPR010664(Protein of unknown function DUF1239)|interpro:IPR026265|refseq:WP_002218352.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015221""(lipopolysaccharide transmembrane transporter activity)|go:""GO:0043165""(Gram-negative-bacterium-type cell outer membrane assembly)|refseq:YP_002348466.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:X2bh/uBtNVh/Wy30Sk+M3ijrZoM9606	rogid:aDJ16CEXIG/yEvICO07srgHr4Ik632	intact-crc:EB648CB9DE3635CD|rigid:oAME1nz4tjMjpRFNYdiELMO3UFQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q4LDE5	uniprotkb:Q8D1N3	intact:EBI-2798103|ensembl:ENSP00000363593.2|uniprotkb:Q96JU7|uniprotkb:Q5VTE5|uniprotkb:Q5D213|uniprotkb:Q0P675|uniprotkb:Q9H284|uniprotkb:Q5T938|uniprotkb:Q9H8J9|uniprotkb:Q5VTE4|uniprotkb:Q7Z3G3|uniprotkb:Q7Z387|uniprotkb:Q8NBT9	intact:EBI-2857870|uniprotkb:Q74PJ0	psi-mi:svep1_human(display_long)|uniprotkb:C9orf13(gene name synonym)|uniprotkb:CCP22(gene name synonym)|uniprotkb:SELOB(gene name synonym)|uniprotkb:CCP module-containing protein 22(gene name synonym)|uniprotkb:Polydom(gene name synonym)|uniprotkb:Selectin-like osteoblast-derived protein(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-38(gene name synonym)|uniprotkb:SVEP1(gene name)|psi-mi:SVEP1(display_short)	"psi-mi:q8d1n3_yerpe(display_long)|uniprotkb:ddg(gene name)|psi-mi:ddg(display_short)|uniprotkb:""Kdo(2)-lipid IV(A) acyltransferase""(gene name synonym)|uniprotkb:lpxP(gene name synonym)|uniprotkb:YP_3915(locus name)|uniprotkb:y0236(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857875|imex:IM-13779-6249	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165124.19(gene)|ensembl:ENST00000374469.6(transcript)|go:""GO:0003017""(lymph circulation)|go:""GO:0003682""(chromatin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008544""(epidermis development)|go:""GO:0010467""(gene expression)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0016020""(membrane)|go:""GO:0036303""(lymph vessel morphogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0048014""(Tie signaling pathway)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0120193""(tight junction organization)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001759(Pentaxin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003410(Hyalin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011641(GCC2 and GCC3)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR035976|interpro:IPR036465|interpro:IPR049883|interpro:IPR050350|mint:Q4LDE5|refseq:NP_699197.3|panther:PTHR19325(orthology-group)"	"interpro:IPR004960(Bacterial lipid A biosynthesis acyltransferase)|interpro:IPR011920(""Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase"")|interpro:IPR030857|go:""GO:0005886""(plasma membrane)|go:""GO:0008951""(palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity)|go:""GO:0009103""(lipopolysaccharide biosynthetic process)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0009409""(response to cold)|go:""GO:0036104""(Kdo2-lipid A biosynthetic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Eql8u2cebsRMv79rjBrmS/0b9Ec9606	rogid:SW0QW9yLuNQPaiMkw6xuT9CL7B0632	intact-crc:37666B937CCCBFF5|rigid:0MNm2lC8wo/08CWhgyjuYbr/gPg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B3KX85	uniprotkb:Q8D020	intact:EBI-36480973	intact:EBI-2841685|uniprotkb:Q74WI5	psi-mi:b3kx85_human(display_long)	psi-mi:q8d020_yerpe(display_long)|uniprotkb:bglA(gene name)|psi-mi:bglA(display_short)|uniprotkb:y2932(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857904|imex:IM-13779-6251	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_787114.2|interpro:IPR003616(Post-SET zinc-binding region)	"interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR018120|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR033132|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005975""(carbohydrate metabolic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RX0deSEMuXA+Zk5CUgfJnKF8sDc9606	rogid:FIpi7GKMp+RoIo3dUToc4hru/9o632	intact-crc:D271AE154FCB76E4|rigid:gvQve8hO4peKnoJdW+mo5mwCKWM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BEU0	uniprotkb:B3KX85	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	intact:EBI-36480973	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	psi-mi:b3kx85_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857925|imex:IM-13779-6253	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	refseq:NP_787114.2|interpro:IPR003616(Post-SET zinc-binding region)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	rogid:RX0deSEMuXA+Zk5CUgfJnKF8sDc9606	intact-crc:6C1E4CA0D40D317E|rigid:ea+ZEu/AoACnTnoFamvjlyjOq/A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PJE2	uniprotkb:B3KX85	intact:EBI-2850829|uniprotkb:Q74WU5|uniprotkb:Q0WC89|uniprotkb:Q7CK47|uniprotkb:A0A384L2F1	intact:EBI-36480973	psi-mi:a0a2s9pje2_yerpe(display_long)|uniprotkb:ahpC(gene name)|psi-mi:ahpC(display_short)|uniprotkb:YPO3194(locus name)	psi-mi:b3kx85_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857918|imex:IM-13779-6252	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013766(Thioredoxin domain)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|refseq:WP_002208675.1|go:""GO:0005829""(cytosol)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0045454""(cell redox homeostasis)|interpro:IPR036249|refseq:YP_002348099.1|interpro:IPR050217|panther:PTHR10681(orthology-group)"	refseq:NP_787114.2|interpro:IPR003616(Post-SET zinc-binding region)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GnZEc/ZzTTpq4nrPnH46z4CNIwg632	rogid:RX0deSEMuXA+Zk5CUgfJnKF8sDc9606	intact-crc:E6D02DF5E8109BB4|rigid:iCjsnb79t/pTjxjw+uNqbyQy/6Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B3KX85	uniprotkb:Q8CWI4	intact:EBI-36480973	intact:EBI-2841215	psi-mi:b3kx85_human(display_long)	psi-mi:q8cwi4_yerpe(display_long)|uniprotkb:kbl(gene name)|psi-mi:kbl(display_short)|uniprotkb:Glycine acetyltransferase(gene name synonym)|uniprotkb:y0081(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857911|imex:IM-13779-6254	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_787114.2|interpro:IPR003616(Post-SET zinc-binding region)	"interpro:IPR011282(2-amino-3-ketobutyrate coenzyme A ligase)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0008890""(glycine C-acetyltransferase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0016874""(ligase activity)|go:""GO:0019518""(L-threonine catabolic process to glycine)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR050087"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RX0deSEMuXA+Zk5CUgfJnKF8sDc9606	rogid:uETD2R/0GvIqPvz6yt39/YuJzJQ632	intact-crc:4246AB424EA86F7A|rigid:qFPKUdHvl2YGilzSozHN/PoUnRE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GWL4	uniprotkb:B3KX85	intact:EBI-2842513|uniprotkb:Q74QF2|uniprotkb:Q0WIK2|uniprotkb:Q7CGX2|uniprotkb:A0A384KBZ2	intact:EBI-36480973	psi-mi:a0a2u2gwl4_yerpe(display_long)|uniprotkb:YPO0835(locus name)	psi-mi:b3kx85_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857932|imex:IM-13779-6255	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004700(Phosphotransferase system, sorbose-specific IIC subunit)|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|refseq:WP_002209879.1|interpro:IPR047835|refseq:YP_002345886.1|interpro:IPR050303|panther:PTHR32502(orthology-group)"	refseq:NP_787114.2|interpro:IPR003616(Post-SET zinc-binding region)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sFFGuU7nv2zkwyFSwvZPy1xxJLc632	rogid:RX0deSEMuXA+Zk5CUgfJnKF8sDc9606	intact-crc:A824B9A22A25C58B|rigid:vQ0QJD6+J0fRZKMx/x1liMRgaoc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C099	uniprotkb:O68723	intact:EBI-725598|intact:EBI-2802231|uniprotkb:Q8N768|uniprotkb:Q96DK7|uniprotkb:Q96N01|uniprotkb:B4DYX6|uniprotkb:B5RI11|ensembl:ENSP00000353538.3	intact:EBI-2857889|uniprotkb:Q74YR2	psi-mi:lrcc1_human(display_long)|uniprotkb:KIAA1764(gene name synonym)|uniprotkb:LRRCC1(gene name)|psi-mi:LRRCC1(display_short)|uniprotkb:CLERC(gene name synonym)|uniprotkb:Centrosomal leucine-rich repeat and coiled-coil domain-containing protein(gene name synonym)	psi-mi:o68723_yerpe(display_long)|uniprotkb:Y1050(locus name)|uniprotkb:YP_pMT006(locus name)|uniprotkb:ORF90(gene name)|psi-mi:ORF90(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857967|imex:IM-13779-6258	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_208325.3|ensembl:ENSG00000133739.16(gene)|ensembl:ENST00000360375.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0051301""(cell division)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|mint:Q9C099|panther:PTHR15454(orthology-group)"	interpro:IPR025484	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uYbYWJqdbQuxk9vvo4N5JVaW8jU9606	rogid:OZFkxl3As03E0sa5pPXdevNZfhM632	intact-crc:678CE235C3F6FFC9|rigid:LTmXpk0JZmv7NylzP3WHWOAwVm0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PIY7	uniprotkb:Q8D1L3	intact:EBI-2802204|uniprotkb:Q86WZ2|uniprotkb:Q8N927|ensembl:ENSP00000296783.3|ensembl:ENSP00000397563.1	intact:EBI-2848215	psi-mi:gld2_human(display_long)|uniprotkb:TENT2(gene name)|psi-mi:TENT2(display_short)|uniprotkb:GLD2(gene name synonym)|uniprotkb:PAP-associated domain-containing protein 4(gene name synonym)|uniprotkb:PAPD4(gene name synonym)|uniprotkb:Terminal nucleotidyltransferase 2(gene name synonym)|uniprotkb:Terminal uridylyltransferase 2(gene name synonym)	psi-mi:q8d1l3_yerpe(display_long)|uniprotkb:ilvE(gene name)|psi-mi:ilvE(display_short)|uniprotkb:y0337(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857939|imex:IM-13779-6260	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001107865.1|refseq:NP_001107866.1|refseq:NP_776158.2|ensembl:ENSG00000164329.15(gene)|ensembl:ENST00000296783.7(transcript)|ensembl:ENST00000453514.6(transcript)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0031380""(nuclear RNA-directed RNA polymerase complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:0140958""(target-directed miRNA degradation)|go:""GO:1990817""(""poly(A) RNA polymerase activity"")|go:""GO:2000626""(negative regulation of miRNA catabolic process)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR043519|interpro:IPR054708|mint:Q6PIY7|refseq:NP_001284673.1|refseq:XP_016864642.1|refseq:XP_016864643.1|refseq:XP_016864644.1|refseq:XP_016864645.1|refseq:XP_016864646.1|refseq:XP_016864647.1|refseq:XP_016864648.1|refseq:XP_016864649.1|panther:PTHR12271(orthology-group)"	"interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR018300|interpro:IPR005785(Branched-chain amino acid aminotransferase I)|interpro:IPR043131|interpro:IPR043132|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0052655""(L-valine-2-oxoglutarate transaminase activity)|go:""GO:0052656""(L-isoleucine-2-oxoglutarate transaminase activity)|interpro:IPR033939|interpro:IPR036038|interpro:IPR050571"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QSN7ZKgdCNKeKfYdAou4NXxqNv89606	rogid:JAIOxo2Y3yD5UWLnGFqrvcdTTQM632	intact-crc:038E83973A68F27B|rigid:qgYCuLby6JK1y2Fahe8MbVfOZWw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q8N7H5	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265.2|uniprotkb:M0QX35	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857946|imex:IM-13779-6256	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:NP_061961.2|refseq:NP_001243755.1|ensembl:ENSG00000006712.15(gene)|ensembl:ENST00000221265.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001650""(fibrillar center)|go:""GO:0001711""(endodermal cell fate commitment)|go:""GO:0003682""(chromatin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016593""(Cdc73/Paf1 complex)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045638""(negative regulation of myeloid cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:1902808""(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|rcsb pdb:7OOP|rcsb pdb:7OPC|rcsb pdb:7OPD|rcsb pdb:7UNC|rcsb pdb:7UND|rcsb pdb:8A3Y|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-48673N|panther:PTHR23188(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606	intact-crc:61661083EF937B9C|rigid:1N0W1eYwK9Bx54je4LKccgMOizM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C099	uniprotkb:Q8D0P9	intact:EBI-725598|intact:EBI-2802231|uniprotkb:Q8N768|uniprotkb:Q96DK7|uniprotkb:Q96N01|uniprotkb:B4DYX6|uniprotkb:B5RI11|ensembl:ENSP00000353538.3	intact:EBI-2856577|uniprotkb:Q74UF2	psi-mi:lrcc1_human(display_long)|uniprotkb:KIAA1764(gene name synonym)|uniprotkb:LRRCC1(gene name)|psi-mi:LRRCC1(display_short)|uniprotkb:CLERC(gene name synonym)|uniprotkb:Centrosomal leucine-rich repeat and coiled-coil domain-containing protein(gene name synonym)	psi-mi:q8d0p9_yerpe(display_long)|uniprotkb:aer(gene name)|psi-mi:aer(display_short)|uniprotkb:YP_1774(locus name)|uniprotkb:y1805(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857953|imex:IM-13779-6259	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_208325.3|ensembl:ENSG00000133739.16(gene)|ensembl:ENST00000360375.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0051301""(cell division)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|mint:Q9C099|panther:PTHR15454(orthology-group)"	"interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR051310|interpro:IPR013655(PAS fold-3)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR035965"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uYbYWJqdbQuxk9vvo4N5JVaW8jU9606	rogid:UQ1nmynYyPCB+ni3UxBTbLxoRNg632	intact-crc:172AE5649C017D57|rigid:YKov9eITEYkuTw+QsLfFzjb0nN4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W3V7	uniprotkb:Q9C099	intact:EBI-2839946|uniprotkb:A0A384LA47|uniprotkb:Q74UY8|uniprotkb:Q0WFV3|uniprotkb:Q7CHZ9|uniprotkb:A0A5P8YEB4	intact:EBI-725598|intact:EBI-2802231|uniprotkb:Q8N768|uniprotkb:Q96DK7|uniprotkb:Q96N01|uniprotkb:B4DYX6|uniprotkb:B5RI11|ensembl:ENSP00000353538.3	psi-mi:a0a0h2w3v7_yerpe(display_long)|uniprotkb:flaV(gene name)|psi-mi:flaV(display_short)|uniprotkb:Flagellar cap protein(gene name synonym)|uniprotkb:flbC(gene name synonym)|uniprotkb:fliD(gene name synonym)|uniprotkb:YPO1841(locus name)	psi-mi:lrcc1_human(display_long)|uniprotkb:KIAA1764(gene name synonym)|uniprotkb:LRRCC1(gene name)|psi-mi:LRRCC1(display_short)|uniprotkb:CLERC(gene name synonym)|uniprotkb:Centrosomal leucine-rich repeat and coiled-coil domain-containing protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857960|imex:IM-13779-6257	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002346835.1|interpro:IPR010809(Flagellar hook-associated 2, C-terminal)|interpro:IPR003481(Flagellar hook-associated protein 2, N-terminal)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0009421""(bacterial-type flagellum filament cap)|go:""GO:0009424""(bacterial-type flagellum hook)|refseq:WP_002211150.1|interpro:IPR040026"	"refseq:NP_208325.3|ensembl:ENSG00000133739.16(gene)|ensembl:ENST00000360375.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0051301""(cell division)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|mint:Q9C099|panther:PTHR15454(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y6JIeGlhmIELicCmvORRUOwywBM632	rogid:uYbYWJqdbQuxk9vvo4N5JVaW8jU9606	intact-crc:0ACC6DDB6A63E2E4|rigid:1FC4ZDMq4hpinKWw/JzGiP5INqY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZFR0	uniprotkb:Q8N512	intact:EBI-2857991|uniprotkb:Q0WGE6	intact:EBI-2857981	psi-mi:pept_yerpe(display_long)|uniprotkb:pepT(gene name)|psi-mi:pepT(display_short)|uniprotkb:Aminotripeptidase(gene name synonym)|uniprotkb:Tripeptide aminopeptidase(gene name synonym)|uniprotkb:YPO1631(locus name)|uniprotkb:y1791(locus name)|uniprotkb:YP_1761(locus name)	psi-mi:q8n512_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857996|imex:IM-13779-6264	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR010161(Peptidase M20B, tripeptide aminopeptidase)|refseq:WP_002210920.1|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0045148""(tripeptide aminopeptidase activity)|interpro:IPR036264|refseq:YP_002346642.1|panther:PTHR42994(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/sFvXfEC4pSnS9aI2zKFcuGUt+k632	rogid:RPi9j78WJ/P3Ki+dh55bSWvXBVY9606	intact-crc:EADB6788B3038B15|rigid:FOA3Upyy46BHv3bTxymRJQP/Ssk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N712	uniprotkb:Q8ZIH1	intact:EBI-2825041	intact:EBI-2841326|uniprotkb:Q0WJD6	psi-mi:q8n712_human(display_long)|uniprotkb:C17orf95(gene name)|psi-mi:C17orf95(display_short)	psi-mi:leud_yerpe(display_long)|uniprotkb:leuD(gene name)|psi-mi:leuD(display_short)|uniprotkb:Alpha-IPM isomerase(gene name synonym)|uniprotkb:Isopropylmalate isomerase(gene name synonym)|uniprotkb:YPO0530(locus name)|uniprotkb:y3648(locus name)|uniprotkb:YP_3652(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857974|imex:IM-13779-6261	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR019410|interpro:IPR029063|go:""GO:0008168""(methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0032991""(protein-containing complex)|refseq:NP_001193914.1"	"interpro:IPR004431(3-isopropylmalate dehydratase, small subunit region)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|go:""GO:0003861""(3-isopropylmalate dehydratase activity)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009316""(3-isopropylmalate dehydratase complex)|refseq:WP_002210456.1|refseq:YP_002345602.1|interpro:IPR033940|interpro:IPR050075|panther:PTHR43345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ObjRrtRynGHGsNEk4dOQBBEKHMY9606	rogid:lF0EK380WhlR7ondVqFIwVAnDFQ632	intact-crc:49EAD2B36C8406EF|rigid:n8Zk3YCA3xELQ2UwmTh9GM3Mw2c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2858006	uniprotkb:Q8D194	-	intact:EBI-2847851|uniprotkb:Q74XR4	psi-mi:q8n2n0_human(display_short)|psi-mi:EBI-2858006(display_long)	psi-mi:q8d194_yerpe(display_long)|uniprotkb:dAK1_1(gene name)|psi-mi:dAK1_1(display_short)|uniprotkb:YP_0337(locus name)|uniprotkb:y0840(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858003|imex:IM-13779-6262	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q8N2N0(uniprot-removed-ac)	"interpro:IPR004006(Dak kinase)|go:""GO:0004371""(glycerone kinase activity)|go:""GO:0006071""(glycerol metabolic process)|interpro:IPR050861"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:PGSwAYXIFUUnJmzpLaHT1vlvQxc632	intact-crc:68EE9F2AFBAEDFB4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N512	uniprotkb:Q8D1L3	intact:EBI-2857981	intact:EBI-2848215	psi-mi:q8n512_human(display_long)	psi-mi:q8d1l3_yerpe(display_long)|uniprotkb:ilvE(gene name)|psi-mi:ilvE(display_short)|uniprotkb:y0337(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2857984|imex:IM-13779-6263	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR018300|interpro:IPR005785(Branched-chain amino acid aminotransferase I)|interpro:IPR043131|interpro:IPR043132|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0052655""(L-valine-2-oxoglutarate transaminase activity)|go:""GO:0052656""(L-isoleucine-2-oxoglutarate transaminase activity)|interpro:IPR033939|interpro:IPR036038|interpro:IPR050571"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RPi9j78WJ/P3Ki+dh55bSWvXBVY9606	rogid:JAIOxo2Y3yD5UWLnGFqrvcdTTQM632	intact-crc:388DB24B3BE0F699|rigid:yXAB/DC+6QR7oxlXIMky7iHEeko	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YAV7	uniprotkb:Q8N2J9	intact:EBI-2839792|uniprotkb:Q74QU9|uniprotkb:Q0WA24|uniprotkb:Q7CG16|uniprotkb:A0A0H2W8V3	intact:EBI-2858012	psi-mi:a0a5p8yav7_yerpe(display_long)|uniprotkb:pelY(gene name)|psi-mi:pelY(display_short)|uniprotkb:YPO3994(locus name)	psi-mi:q8n2j9_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858015|imex:IM-13779-6265	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010702(Periplasmic pectate lyase)|refseq:YP_002348864.1|refseq:WP_002209555.1|go:""GO:0016837""(carbon-oxygen lyase activity, acting on polysaccharides)|go:""GO:0042597""(periplasmic space)|go:""GO:0045490""(pectin catabolic process)"	"interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR020837|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|go:""GO:0007596""(blood coagulation)|interpro:IPR037579|interpro:IPR036056"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TdSmcoWgW+r5eNyU5ieC4Vae68s632	rogid:SSXHgoeqtypb8ygjR5wRpkzPMsg9606	intact-crc:E238F82447990FBF|rigid:ZgkVaep6fV/IEO9Fc4BwI8adk1c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IZ63	uniprotkb:Q8D014	intact:EBI-2858054|uniprotkb:E9PB31|ensembl:ENSP00000407653.2	intact:EBI-2840312|uniprotkb:Q74WE9	psi-mi:prr22_human(display_long)|uniprotkb:PRR22(gene name)|psi-mi:PRR22(display_short)	psi-mi:q8d014_yerpe(display_long)|uniprotkb:nrdB(gene name)|psi-mi:nrdB(display_short)|uniprotkb:y2975(locus name)|uniprotkb:YP_0924(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858058|imex:IM-13779-6266	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001127788.1|ensembl:ENSG00000212123.4(gene)|ensembl:ENST00000419421.3(transcript)|interpro:IPR031535|panther:PTHR37871(orthology-group)	"interpro:IPR033909|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|go:""GO:0004748""(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:""GO:0009263""(deoxyribonucleotide biosynthetic process)|interpro:IPR030475|interpro:IPR012348(Ribonucleotide reductase-related)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0HRs5M1S8mG5+dxEifpTGkOpNsw9606	rogid:cQYray4oIRTe9sYOcO6GpVOCuBc632	intact-crc:490934AF066CBA36|rigid:aWI/CfjyEO79exmjMr/NgmweMjQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHI2	uniprotkb:Q8N287	intact:EBI-2858025|uniprotkb:Q0WIC9	intact:EBI-2858029	psi-mi:y911_yerpe(display_long)|uniprotkb:YPO0911(locus name)|uniprotkb:y3298(locus name)|uniprotkb:YP_3608(locus name)	psi-mi:q8n287_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858022|imex:IM-13779-6267	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011978(YgfB and YecA)|refseq:WP_002209953.1|go:""GO:0005829""(cytosol)|interpro:IPR036255|refseq:YP_002345959.1|panther:PTHR37528(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:K16ujvdzHI3GiDBUXUJUE1Q6g34632	rogid:fDKwugeqo0JpJQqZOUfka27w+t89606	intact-crc:A78CE01E11C6EA2F|rigid:qT5y4a26IZJ9kOvALJCN60HhGaA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IZM6	uniprotkb:Q8ZHZ5	intact:EBI-2858046	intact:EBI-2858039|uniprotkb:Q74RJ1|uniprotkb:Q0WIU8|uniprotkb:Q7CGL0	psi-mi:q8izm6_human(display_long)|uniprotkb:BPGAP1(gene name)|psi-mi:BPGAP1(display_short)	psi-mi:flgh1_yerpe(display_long)|uniprotkb:flgH1(gene name)|psi-mi:flgH1(display_short)|uniprotkb:Basal body L-ring protein 1(gene name synonym)|uniprotkb:YPO0729(locus name)|uniprotkb:y3449(locus name)|uniprotkb:YP_3040(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858036|imex:IM-13779-6268	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0007165""(signal transduction)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030335""(positive regulation of cell migration)|interpro:IPR036865|mint:Q8IZM6"	"interpro:IPR000527(Flagellar L-ring protein)|refseq:WP_002211429.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009427""(bacterial-type flagellum basal body, distal rod, L ring)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:YP_002345790.1|panther:PTHR34933(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PSJDYHCvtZYdpIQwvHUTU86zhP89606	rogid:Q+NSfLft869SSbjMsvF1Op2i/nU632	intact-crc:F260A0BA9985379A|rigid:O2KC+98xu3OTTUwBMnB4jyJUXEY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IZ63	uniprotkb:A0A0H2W9S4	intact:EBI-2858054|uniprotkb:E9PB31|ensembl:ENSP00000407653.2	intact:EBI-2851018|uniprotkb:Q74PV1|uniprotkb:A0A380PJ36|uniprotkb:Q7CG39|uniprotkb:Q0WJR3	psi-mi:prr22_human(display_long)|uniprotkb:PRR22(gene name)|psi-mi:PRR22(display_short)	psi-mi:a0a0h2w9s4_yerpe(display_long)|uniprotkb:YPO0398(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858072|imex:IM-13779-6272	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001127788.1|ensembl:ENSG00000212123.4(gene)|ensembl:ENST00000419421.3(transcript)|interpro:IPR031535|panther:PTHR37871(orthology-group)	"interpro:IPR001915(Peptidase M48, Ste24p)|refseq:WP_002209176.1|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:YP_002345475.1|interpro:IPR051156"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0HRs5M1S8mG5+dxEifpTGkOpNsw9606	rogid:hu7ik6gGx0jCcFmvYlH72f4i/p4632	intact-crc:4B67BE5F3A46CE06|rigid:f/hZYCwjyi1iluEp7nZ/Nz2zbR8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B652	uniprotkb:Q8IZ03	intact:EBI-2841456|uniprotkb:Q74UD2|uniprotkb:A0A0H2W5A2|uniprotkb:Q7CIY7	intact:EBI-746217|intact:EBI-12169379|intact:EBI-12754659	psi-mi:a0a3n4b652_yerpe(display_long)|uniprotkb:cheA(gene name)|psi-mi:cheA(display_short)|uniprotkb:YPO1666(locus name)	psi-mi:q8iz03_human(display_long)|uniprotkb:IFIT2(gene name)|psi-mi:IFIT2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858079|imex:IM-13779-6270	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR002545(CheW-like protein)|interpro:IPR015162(CheY binding)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR008207(""Signal transduction histidine kinase, phosphotransfer (Hpt) region"")|interpro:IPR004105(Signal transduction histidine kinase, subgroup, homodimeric)|interpro:IPR005467(Signal transduction histidine kinase, core)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006935""(chemotaxis)|refseq:YP_002346673.1|interpro:IPR035891|interpro:IPR036061|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037006|interpro:IPR051315|panther:PTHR43395(orthology-group)"	"go:""GO:0051707""(response to other organism)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KztfI7bmNuR6U1Zo6bOZct0DtBc632	rogid:bDd9CPSoKMqKgT2p7JDx583lLYM9606	intact-crc:FEA04616370F45F7|rigid:OJ4a0noPiLgCam3437DuDgQW/Zo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIL4	uniprotkb:Q8IZ03	intact:EBI-2852663|uniprotkb:Q0WJI3	intact:EBI-746217|intact:EBI-12169379|intact:EBI-12754659	psi-mi:carb_yerpe(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:YPO0482(locus name)|uniprotkb:YP_3697(locus name)|uniprotkb:y3692(locus name)	psi-mi:q8iz03_human(display_long)|uniprotkb:IFIT2(gene name)|psi-mi:IFIT2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858093|imex:IM-13779-6273	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|refseq:WP_002210502.1|go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR033937|interpro:IPR036897|interpro:IPR036914|refseq:YP_002345555.1|panther:PTHR11405(orthology-group)"	"go:""GO:0051707""(response to other organism)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l/RzabCD1P/dEo/AmaYoXpYV1FY632	rogid:bDd9CPSoKMqKgT2p7JDx583lLYM9606	intact-crc:20BEA1C776EDCCBC|rigid:ISqV1jrveQMWmgHGr1co0Nt3fSQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IZ63	uniprotkb:A0A2U2GVZ6	intact:EBI-2858054|uniprotkb:E9PB31|ensembl:ENSP00000407653.2	intact:EBI-2842971|uniprotkb:Q74W16|uniprotkb:A0A0H2W2X1|uniprotkb:Q7CJU6|uniprotkb:A0A3N4AZS9|uniprotkb:A0A384L7G7	psi-mi:prr22_human(display_long)|uniprotkb:PRR22(gene name)|psi-mi:PRR22(display_short)	psi-mi:a0a2u2gvz6_yerpe(display_long)|uniprotkb:ubiF(gene name)|psi-mi:ubiF(display_short)|uniprotkb:YPO2621(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858065|imex:IM-13779-6269	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001127788.1|ensembl:ENSG00000212123.4(gene)|ensembl:ENST00000419421.3(transcript)|interpro:IPR031535|panther:PTHR37871(orthology-group)	"interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR010971(Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6)|go:""GO:0004497""(monooxygenase activity)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0016705""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:""GO:0071949""(FAD binding)|refseq:WP_002210347.1|interpro:IPR036188|refseq:YP_002347577.1|interpro:IPR051205"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0HRs5M1S8mG5+dxEifpTGkOpNsw9606	rogid:zKOVHd4RmzcakJDi4rlK0Xy9yNc632	intact-crc:FB8F4A8481D417C6|rigid:X730uoKTXLJA3tnwpm9VxwbfErc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46359	uniprotkb:Q8IZ03	intact:EBI-2844956|uniprotkb:Q0WFP1	intact:EBI-746217|intact:EBI-12169379|intact:EBI-12754659	psi-mi:fyua_yerpe(display_long)|uniprotkb:fyuA(gene name)|psi-mi:fyuA(display_short)|uniprotkb:psn(gene name synonym)|uniprotkb:IRPC(gene name synonym)|uniprotkb:YPO1906(locus name)|uniprotkb:y2404(locus name)|uniprotkb:YP_1649(locus name)	psi-mi:q8iz03_human(display_long)|uniprotkb:IFIT2(gene name)|psi-mi:IFIT2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858086|imex:IM-13779-6271	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|rcsb pdb:4EPA|go:""GO:0009279""(cell outer membrane)|go:""GO:0015344""(siderophore uptake transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0044718""(siderophore transmembrane transport)|refseq:WP_002212885.1|interpro:IPR036942|interpro:IPR039426|refseq:YP_002346897.1|panther:PTHR30069(orthology-group)"	"go:""GO:0051707""(response to other organism)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sl/8Ppm/ZorktNWh6kbdsQhE1JA632	rogid:bDd9CPSoKMqKgT2p7JDx583lLYM9606	intact-crc:DBF4CDCCD9E7D85F|rigid:ep3cMyAsyDfOKfY5P/ROfNw58oI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZEL9	uniprotkb:Q8IYZ2	intact:EBI-2858120|uniprotkb:Q0WF17	intact:EBI-2858105	psi-mi:fadr_yerpe(display_long)|uniprotkb:fadR(gene name)|psi-mi:fadR(display_short)|uniprotkb:YPO2144(locus name)|uniprotkb:y2177(locus name)|uniprotkb:YP_1946(locus name)	psi-mi:q8iyz2_human(display_long)|uniprotkb:ZNF521(gene name)|psi-mi:ZNF521(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858117|imex:IM-13779-6274	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014178(Fatty acid response transcription factor FadR)|interpro:IPR008920(Fatty acid responsive transcription factor FadR, C-terminal)|interpro:IPR000524(Bacterial regulatory protein GntR, HTH)|interpro:IPR028374|refseq:WP_002211688.1|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0019217""(regulation of fatty acid metabolic process)|interpro:IPR036388|interpro:IPR036390|refseq:YP_002347121.1|panther:PTHR43537(orthology-group)"	refseq:NP_001295154.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BtgcqSpKLgoqX7IWTz50Z6ZY5/w632	rogid:srjl07kl9qH3wUwlrdJulKTSNYQ9606	intact-crc:3B53F2540677A606|rigid:LLvzb06j8fen96YoLSGD2hntpi0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IYZ2	uniprotkb:A0A2U2GWS2	intact:EBI-2858105	intact:EBI-2858100|uniprotkb:Q74SR6|uniprotkb:A0A0H2W634|uniprotkb:Q7CJQ7|uniprotkb:A0A384KQD2	psi-mi:q8iyz2_human(display_long)|uniprotkb:ZNF521(gene name)|psi-mi:ZNF521(display_short)	psi-mi:a0a2u2gws2_yerpe(display_long)|uniprotkb:rseB(gene name)|psi-mi:rseB(display_short)|uniprotkb:YPO2713(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858110|imex:IM-13779-6276	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001295154.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	"interpro:IPR033434|interpro:IPR033436|interpro:IPR005588(MucB/RseB)|refseq:WP_002209674.1|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0032885""(regulation of polysaccharide biosynthetic process)|go:""GO:0045152""(antisigma factor binding)|interpro:IPR038484|refseq:YP_002347660.1|panther:PTHR38782(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:srjl07kl9qH3wUwlrdJulKTSNYQ9606	rogid:CKCZ9xitf23bxFI4wCD7b8J8aLo632	intact-crc:08A0CDDBBFF7BED0|rigid:wAjOv5uTQ4aL+Py3YpqLrElV9gE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q49A88	uniprotkb:A0A2S9PJH3	intact:EBI-751035|intact:EBI-2622203|intact:EBI-2858142|uniprotkb:B7Z2T2|uniprotkb:B8ZZ58|intact:EBI-946963|intact:EBI-1104778|uniprotkb:Q7Z3N3|uniprotkb:Q86T30|uniprotkb:Q8WUJ8|uniprotkb:Q96K47|uniprotkb:Q9H9A3|uniprotkb:Q9UFH0|uniprotkb:Q8IWF8|uniprotkb:B8ZZ41|uniprotkb:D3DN98|uniprotkb:B7Z2Q3	intact:EBI-2839884|uniprotkb:Q7CIZ2|uniprotkb:Q0WGC0	psi-mi:ccd14_human(display_long)|uniprotkb:CCDC14(gene name)|psi-mi:CCDC14(display_short)	psi-mi:a0a2s9pjh3_yerpe(display_long)|uniprotkb:mgtC(gene name)|psi-mi:mgtC(display_short)|uniprotkb:YPO1660(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858139|imex:IM-13779-6277	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_073594.4|refseq:XP_005247767.1|refseq:XP_005247768.1|refseq:XP_005247770.1|refseq:XP_005247771.1|refseq:NP_001295246.1|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0021762""(substantia nigra development)|go:""GO:0034451""(centriolar satellite)|go:""GO:0071539""(protein localization to centrosome)|interpro:IPR029343|refseq:XP_016862545.1|refseq:XP_016862547.1|refseq:XP_016862548.1|mint:Q49A88|dip:DIP-47727N|panther:PTHR22367(orthology-group)"	"interpro:IPR003416(MgtC/SapB transporter)|interpro:IPR048640|interpro:IPR049177|go:""GO:0005886""(plasma membrane)|refseq:YP_002346668.1|panther:PTHR33778(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:y1bU4io/NA6LIX+pwRkB8gstVuY9606	rogid:uPB8dbfu1Sb5/L3fJ2zFWCc7gWs632	intact-crc:F08FE5E8586B65E5|rigid:pAtB+2Xf0MwSShY5mVq/gIG6lkk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IX62	uniprotkb:A0A0H2W0I2	intact:EBI-2858129	intact:EBI-2847735|uniprotkb:Q74XP3|uniprotkb:Q0WBW4|uniprotkb:Q7CKA9|uniprotkb:A0A384L3M8	psi-mi:q8ix62_human(display_long)	psi-mi:a0a0h2w0i2_yerpe(display_long)|uniprotkb:YPO3328(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858132|imex:IM-13779-6275	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010630(Protein of unknown function DUF1220)|go:""GO:0005737""(cytoplasm)|interpro:IPR055306"	"interpro:IPR025997|interpro:IPR028082|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002348224.1|interpro:IPR050555"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wwAchIrFI2hAPvu/38Yr7AS91BU9606	rogid:HHGoonb2nUNXAajQaaTnNuqKf7g632	intact-crc:45EC2BF83AC093BB|rigid:ywLVzT5f74rXmPZJPqVhJpsiYBw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PFE9	uniprotkb:Q8IUP8	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	intact:EBI-2825155	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	psi-mi:q8iup8_human(display_long)|uniprotkb:PCDH12(gene name)|psi-mi:PCDH12(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858177|imex:IM-13779-6281	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR013164(Cadherin, N-terminal)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|interpro:IPR050174"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	rogid:oJdBVEYKg3bFf7UtgiqLttU4hkA9606	intact-crc:E7FA263E9084FABB|rigid:cIT79+nwbD1QyPL0fYM27gIzTEY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86XR2	uniprotkb:Q8ZHI8	intact:EBI-2796690|uniprotkb:Q7Z6H6|uniprotkb:Q8TEQ3|uniprotkb:Q86XR3|uniprotkb:Q86XR4|uniprotkb:B4DNU3|uniprotkb:B4DVN7|ensembl:ENSP00000335040.3	intact:EBI-2853665|uniprotkb:Q0WID5	psi-mi:niba3_human(display_long)|uniprotkb:NIBAN3(gene name)|psi-mi:NIBAN3(display_short)|uniprotkb:BCNP1(gene name synonym)|uniprotkb:FAM129C(gene name synonym)|uniprotkb:B-cell novel protein 1(gene name synonym)|uniprotkb:Niban-like protein 2(gene name synonym)|uniprotkb:Protein FAM129C(gene name synonym)	"psi-mi:gcsp_yerpe(display_long)|uniprotkb:gcvP(gene name)|psi-mi:gcvP(display_short)|uniprotkb:Glycine cleavage system P-protein(gene name synonym)|uniprotkb:Glycine decarboxylase(gene name synonym)|uniprotkb:""Glycine dehydrogenase (aminomethyl-transferring)""(gene name synonym)|uniprotkb:YPO0905(locus name)|uniprotkb:YP_3602(locus name)|uniprotkb:y3292(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858194|imex:IM-13779-6280	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001091994.1|refseq:NP_775815.2|refseq:NP_001308756.1|refseq:NP_001308757.1|ensembl:ENSG00000167483.19(gene)|ensembl:ENST00000335393.8(transcript)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR026088|panther:PTHR14392(orthology-group)	"refseq:WP_002209947.1|interpro:IPR020581|interpro:IPR003437(Glycine cleavage system P-protein)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:""GO:0004375""(""glycine dehydrogenase (decarboxylating) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0016594""(glycine binding)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR049315|interpro:IPR049316|refseq:YP_002345953.1|panther:PTHR11773(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1OT0PKDbrs+XgxgpZMW0tfzn5789606	rogid:DyITTFcMLNG19IvzD1ZE6K5EW/U632	intact-crc:0AAF45833E2FAF9C|rigid:irgGD3eb5ohuuY6WGDag3NAt0Dk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKC4	uniprotkb:Q15751	intact:EBI-2858163	intact:EBI-2682261|uniprotkb:Q8IW65|intact:EBI-2825112|intact:EBI-28971771|ensembl:ENSP00000390158.2	psi-mi:q8ckc4_yerpe(display_long)|uniprotkb:y3735(locus name)	psi-mi:herc1_human(display_long)|uniprotkb:HECT domain and RCC1-like domain-containing protein 1(gene name synonym)|uniprotkb:p532(gene name synonym)|uniprotkb:p619(gene name synonym)|uniprotkb:HERC1(gene name)|psi-mi:HERC1(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase HERC1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858160|imex:IM-13779-6282	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR025230|go:""GO:0005524""(ATP binding)|interpro:IPR036388|interpro:IPR036597|interpro:IPR040198"	"efo:""Orphanet:457359""|ensembl:ENSG00000103657.14(gene)|ensembl:ENST00000443617.7(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021702""(cerebellar Purkinje cell differentiation)|go:""GO:0022038""(corpus callosum development)|go:""GO:0031175""(neuron projection development)|go:""GO:0050885""(neuromuscular process controlling balance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000569(HECT)|interpro:IPR001680(WD40 repeat)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR035768|interpro:IPR035983|interpro:IPR036322|interpro:IPR043136|interpro:IPR051625|mint:Q15751|rcsb pdb:4O2W|rcsb pdb:4QT6|reactome:R-HSA-983168|refseq:NP_003913.3|panther:PTHR22870(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SV9JzJXwBnZ1/hewWFARzQUzhxI632	rogid:E4Noy/4r/V1MyW8d8PZPsX36in09606	intact-crc:2A1131709E25F9EC|rigid:/4FcZAtSCtiSxEQdzJU+JpXRO8M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15751	uniprotkb:Q7CIZ3	intact:EBI-2682261|uniprotkb:Q8IW65|intact:EBI-2825112|intact:EBI-28971771|ensembl:ENSP00000390158.2	intact:EBI-2852946|uniprotkb:Q74UE1	psi-mi:herc1_human(display_long)|uniprotkb:HECT domain and RCC1-like domain-containing protein 1(gene name synonym)|uniprotkb:p532(gene name synonym)|uniprotkb:p619(gene name synonym)|uniprotkb:HERC1(gene name)|psi-mi:HERC1(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase HERC1(gene name synonym)	psi-mi:bgal_yerpe(display_long)|uniprotkb:lacZ(gene name)|psi-mi:lacZ(display_short)|uniprotkb:Lactase(gene name synonym)|uniprotkb:YPO1654(locus name)|uniprotkb:y1817(locus name)|uniprotkb:YP_1785(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858170|imex:IM-13779-6278	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:457359""|ensembl:ENSG00000103657.14(gene)|ensembl:ENST00000443617.7(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021702""(cerebellar Purkinje cell differentiation)|go:""GO:0022038""(corpus callosum development)|go:""GO:0031175""(neuron projection development)|go:""GO:0050885""(neuromuscular process controlling balance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000569(HECT)|interpro:IPR001680(WD40 repeat)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR035768|interpro:IPR035983|interpro:IPR036322|interpro:IPR043136|interpro:IPR051625|mint:Q15751|rcsb pdb:4O2W|rcsb pdb:4QT6|reactome:R-HSA-983168|refseq:NP_003913.3|panther:PTHR22870(orthology-group)"	"interpro:IPR050347|interpro:IPR008979(Galactose-binding like)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR014718(Glycoside hydrolase-type carbohydrate-binding, subgroup)|interpro:IPR006101(Glycoside hydrolase, family 2)|interpro:IPR023232|interpro:IPR023933|interpro:IPR023230|interpro:IPR004199(Glycoside hydrolase, family 42, domain 5)|interpro:IPR006102(Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich)|interpro:IPR006104(Glycoside hydrolase family 2, carbohydrate-binding)|interpro:IPR006103(Glycoside hydrolase family 2, TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002214048.1|interpro:IPR032312|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004565""(beta-galactosidase activity)|go:""GO:0005990""(lactose catabolic process)|go:""GO:0009341""(beta-galactosidase complex)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036156|refseq:YP_002346664.1|panther:PTHR46323(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E4Noy/4r/V1MyW8d8PZPsX36in09606	rogid:RFOxfJbd+ZN/lJ/fIfkqbMSwF7w632	intact-crc:FFD2678940B471C8|rigid:w+dpT6maqSH2nnTUkV2pKGobtkc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IUN7	uniprotkb:Q7ARD3	intact:EBI-2858184|uniprotkb:E9PBI1|ensembl:ENSP00000378358.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:q8iun7_human(display_long)|uniprotkb:ADH6(gene name)|psi-mi:ADH6(display_short)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858187|imex:IM-13779-6279	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000663.1|refseq:NP_001095940.1|ensembl:ENSG00000172955.17(gene)|ensembl:ENST00000394897.5(transcript)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR036291"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+L2fGtsDiprLO2xRAqcGcdYh8oo9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:4C9D7DB30DA61F0B|rigid:RoA2k4zDjBptu7o5io4ROVFq6+I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16822	uniprotkb:Q8CZS2	intact:EBI-2825219|uniprotkb:O43253|uniprotkb:Q9BV62|intact:EBI-3189808|uniprotkb:Q86U01|ensembl:ENSP00000216780.4|ensembl:ENSP00000494919.1|uniprotkb:B4DW73	intact:EBI-2845681	psi-mi:pckgm_human(display_long)|uniprotkb:PCK2(gene name)|psi-mi:PCK2(display_short)|uniprotkb:PEPCK2(gene name synonym)|uniprotkb:Phosphoenolpyruvate carboxykinase 2, mitochondrial(gene name synonym)	psi-mi:q8czs2_yerpe(display_long)|uniprotkb:icc(gene name)|psi-mi:icc(display_short)|uniprotkb:y3513(locus name)|uniprotkb:cpdA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858231|imex:IM-13779-6285	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100889.12(gene)|ensembl:ENSG00000285241.2(gene)|ensembl:ENST00000216780.9(transcript)|ensembl:ENST00000645217.2(transcript)|go:""GO:0004611""(phosphoenolpyruvate carboxykinase activity)|go:""GO:0004613""(""phosphoenolpyruvate carboxykinase (GTP) activity"")|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006107""(oxaloacetate metabolic process)|go:""GO:0006116""(obsolete NADH oxidation)|go:""GO:0019543""(propionate catabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0042594""(response to starvation)|go:""GO:0046327""(glycerol biosynthetic process from pyruvate)|go:""GO:0070365""(hepatocyte differentiation)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|interpro:IPR008209(Phosphoenolpyruvate carboxykinase, GTP-utilising)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR018091|interpro:IPR035077|interpro:IPR035078|mint:Q16822|reactome:R-HSA-70263|refseq:NP_001018083.2|refseq:NP_001278485.1|refseq:NP_001294983.1|refseq:NP_004554.3|efo:""Orphanet:2880""|panther:PTHR11561(orthology-group)"	"interpro:IPR026575|interpro:IPR046379|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|go:""GO:0000166""(nucleotide binding)|go:""GO:0004115""(3',5'-cyclic-AMP phosphodiesterase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR050884"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gbQbu8+tVa1xs/fKesefSJlpSaM9606	rogid:pHtA80uk66ZaIBbjEM2kYqV0pog632	intact-crc:FCA98D68007373D1|rigid:NtrkPhCmT2AaaQSLlGZ+IPNPOIA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PDF6	uniprotkb:Q86UY0	intact:EBI-2856702|uniprotkb:Q74UZ3|uniprotkb:Q7CI04|uniprotkb:A0A0H2W3V4	intact:EBI-2825190|intact:EBI-11955035|intact:EBI-12742613	psi-mi:a0a380pdf6_yerpe(display_long)|uniprotkb:yecS(gene name)|psi-mi:yecS(display_short)|uniprotkb:YPO1847(locus name)	psi-mi:q86uy0_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858224|imex:IM-13779-6284	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_002211158.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015184""(L-cystine transmembrane transporter activity)|go:""GO:0015811""(L-cystine transport)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|interpro:IPR035906|interpro:IPR043429|refseq:YP_002346841.1|panther:PTHR30614(orthology-group)"	"interpro:IPR005788(Disulphide isomerase)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0005788""(endoplasmic reticulum lumen)|interpro:IPR036249|interpro:IPR051063"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pJ27jWvWt/SRd2N+cRvIV71qr60632	rogid:KU14gIY2qRj+zg/dhVy0khrsfU09606	intact-crc:2F2F8BC65D364F6D|rigid:dVMiS985zwK3AM+0FLvNaaaLeO8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PBF6	uniprotkb:Q86VE0	intact:EBI-2858208|uniprotkb:Q74RW5|uniprotkb:Q7CGC7|uniprotkb:A0A3N4BUB9|uniprotkb:Q0WJ85	intact:EBI-2858213|ensembl:ENSP00000325402.4	psi-mi:a0a2s9pbf6_yerpe(display_long)|uniprotkb:uxaA(gene name)|psi-mi:uxaA(display_short)|uniprotkb:YPO0581(locus name)	psi-mi:mypop_human(display_long)|uniprotkb:MYPOP(gene name)|psi-mi:MYPOP(display_short)|uniprotkb:P42POP(gene name synonym)|uniprotkb:Myb-related protein p42POP(gene name synonym)|uniprotkb:Partner of profilin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858217|imex:IM-13779-6286	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007392(D-galactarate dehydratase/Altronate hydrolase, C-terminal)|interpro:IPR013974(SAF domain)|interpro:IPR044144|interpro:IPR052172|refseq:WP_002210408.1|go:""GO:0016787""(hydrolase activity)|go:""GO:0016829""(lyase activity)|interpro:IPR048332|refseq:YP_002345653.1"	"refseq:NP_001012661.1|ensembl:ENSG00000176182.6(gene)|ensembl:ENST00000322217.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR028002|interpro:IPR052870|panther:PTHR32345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HPdHp8PXEzf8Z8gFJJj/FAsINEk632	rogid:Vdwo3nlDWx6nLVRBLCqgQSl869g9606	intact-crc:E84E443B5E2566DD|rigid:Z+mtNZurB2jloSaz1o9FaozSpbM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86XI8	uniprotkb:Q8D1C5	intact:EBI-2682158|ensembl:ENSP00000331363.7|uniprotkb:A0A087WWL5	intact:EBI-2842614	psi-mi:zswm9_human(display_long)|uniprotkb:ZSWIM9(gene name)|psi-mi:ZSWIM9(display_short)|uniprotkb:C19orf68(gene name synonym)	psi-mi:q8d1c5_yerpe(display_long)|uniprotkb:phnI(gene name)|psi-mi:phnI(display_short)|uniprotkb:y0727(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858201|imex:IM-13779-6283	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_955373.3|refseq:XP_006723268.1|ensembl:ENSG00000185453.13(gene)|ensembl:ENST00000328759.11(transcript)|interpro:IPR040854|interpro:IPR048315|interpro:IPR049217|interpro:IPR049218|mint:Q86XI8|panther:PTHR47086(orthology-group)	"interpro:IPR008773(Phosphonate metabolism)|go:""GO:0019634""(organic phosphonate metabolic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4wOy3iLGFg7lgvbA8nWPUgIgS0w9606	rogid:AbNsdhrfAkwhBQT3IgXGyOmugPY632	intact-crc:BE97DA2AE96B7F4F|rigid:PUxsHFLG8VCvHPO6mWvOU3n9gmE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16822	uniprotkb:A0A2U2H0W0	intact:EBI-2825219|uniprotkb:O43253|uniprotkb:Q9BV62|intact:EBI-3189808|uniprotkb:Q86U01|ensembl:ENSP00000216780.4|ensembl:ENSP00000494919.1|uniprotkb:B4DW73	intact:EBI-2857561|uniprotkb:Q74U91|uniprotkb:Q0WFF6|uniprotkb:A0A380PDB4|uniprotkb:Q7CI92|uniprotkb:A0A384L848	psi-mi:pckgm_human(display_long)|uniprotkb:PCK2(gene name)|psi-mi:PCK2(display_short)|uniprotkb:PEPCK2(gene name synonym)|uniprotkb:Phosphoenolpyruvate carboxykinase 2, mitochondrial(gene name synonym)	psi-mi:a0a2u2h0w0_yerpe(display_long)|uniprotkb:YPO1997(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858238|imex:IM-13779-6287	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100889.12(gene)|ensembl:ENSG00000285241.2(gene)|ensembl:ENST00000216780.9(transcript)|ensembl:ENST00000645217.2(transcript)|go:""GO:0004611""(phosphoenolpyruvate carboxykinase activity)|go:""GO:0004613""(""phosphoenolpyruvate carboxykinase (GTP) activity"")|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006107""(oxaloacetate metabolic process)|go:""GO:0006116""(obsolete NADH oxidation)|go:""GO:0019543""(propionate catabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0042594""(response to starvation)|go:""GO:0046327""(glycerol biosynthetic process from pyruvate)|go:""GO:0070365""(hepatocyte differentiation)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|interpro:IPR008209(Phosphoenolpyruvate carboxykinase, GTP-utilising)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR018091|interpro:IPR035077|interpro:IPR035078|mint:Q16822|reactome:R-HSA-70263|refseq:NP_001018083.2|refseq:NP_001278485.1|refseq:NP_001294983.1|refseq:NP_004554.3|efo:""Orphanet:2880""|panther:PTHR11561(orthology-group)"	interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR052750|interpro:IPR029058|refseq:WP_002211257.1|refseq:YP_002346982.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gbQbu8+tVa1xs/fKesefSJlpSaM9606	rogid:DP6LxF8YTJKUt3yW/2M2CRKvosU632	intact-crc:2CA26EAB900DBBB0|rigid:aUsYEafFw6jElALHpCwWKGiTC/Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9F287	uniprotkb:Q86TG7	intact:EBI-2854744|uniprotkb:Q7CGE2|uniprotkb:A0A384KA49|uniprotkb:A0A1U8QHS7|uniprotkb:A0A454XLL2	intact:EBI-2858265|uniprotkb:Q9UPV1|uniprotkb:Q96A68|uniprotkb:B4DSP0	psi-mi:q9f287_yerpe(display_long)|uniprotkb:yapF(gene name)|psi-mi:yapF(display_short)|uniprotkb:YPO0606(locus name)	psi-mi:peg10_human(display_long)|uniprotkb:PEG10(gene name)|psi-mi:PEG10(display_short)|uniprotkb:EDR(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:MART2(gene name synonym)|uniprotkb:MEF3L1(gene name synonym)|uniprotkb:RGAG3(gene name synonym)|uniprotkb:Embryonal carcinoma differentiation-regulated protein(gene name synonym)|uniprotkb:Mammalian retrotransposon-derived protein 2(gene name synonym)|uniprotkb:Myelin expression factor 3-like protein 1(gene name synonym)|uniprotkb:Paternally expressed gene 10 protein(gene name synonym)|uniprotkb:Retrotransposon gag domain-containing protein 3(gene name synonym)|uniprotkb:Retrotransposon-derived gag-like polyprotein(gene name synonym)|uniprotkb:Ty3/Gypsy-like protein(gene name synonym)|uniprotkb:KIAA1051e(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858271|imex:IM-13779-6289	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR005546(Autotransporter beta-domain)|refseq:WP_002210389.1|interpro:IPR036709|refseq:YP_002345675.1	"refseq:NP_001035242.1|refseq:NP_001171890.1|refseq:NP_001171891.1|refseq:NP_055883.2|interpro:IPR021109|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR032549|interpro:IPR032567|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0051028""(mRNA transport)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0075523""(viral translational frameshifting)|go:""GO:0110077""(vesicle-mediated intercellular transport)|go:""GO:1903561""(extracellular vesicle)|rcsb pdb:7LGA|interpro:IPR036875|interpro:IPR043128|interpro:IPR043502|mint:Q86TG7|refseq:NP_001165908.1|refseq:NP_001165909.1|panther:PTHR15503(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uIQ9881A2N1D063pjSQtEbbJqNs632	rogid:wkCBsH9/PsFMwJFu/qOwZcn63D49606	intact-crc:2E7CB6E333A87C51|rigid:QAYKShft/Ttt3GiLj7FcqDL1a08	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ79	uniprotkb:Q16822	intact:EBI-2848724|uniprotkb:Q0WK65	intact:EBI-2825219|uniprotkb:O43253|uniprotkb:Q9BV62|intact:EBI-3189808|uniprotkb:Q86U01|ensembl:ENSP00000216780.4|ensembl:ENSP00000494919.1|uniprotkb:B4DW73	psi-mi:def_yerpe(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:Polypeptide deformylase(gene name synonym)|uniprotkb:YPO0242(locus name)|uniprotkb:y4023(locus name)|uniprotkb:YP_0240(locus name)	psi-mi:pckgm_human(display_long)|uniprotkb:PCK2(gene name)|psi-mi:PCK2(display_short)|uniprotkb:PEPCK2(gene name synonym)|uniprotkb:Phosphoenolpyruvate carboxykinase 2, mitochondrial(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858245|imex:IM-13779-6290	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023635|refseq:WP_002209021.1|go:""GO:0006412""(translation)|go:""GO:0042586""(peptide deformylase activity)|go:""GO:0043686""(co-translational protein modification)|go:""GO:0046872""(metal ion binding)|interpro:IPR036821|refseq:YP_002345323.1|panther:PTHR10458(orthology-group)"	"ensembl:ENSG00000100889.12(gene)|ensembl:ENSG00000285241.2(gene)|ensembl:ENST00000216780.9(transcript)|ensembl:ENST00000645217.2(transcript)|go:""GO:0004611""(phosphoenolpyruvate carboxykinase activity)|go:""GO:0004613""(""phosphoenolpyruvate carboxykinase (GTP) activity"")|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006107""(oxaloacetate metabolic process)|go:""GO:0006116""(obsolete NADH oxidation)|go:""GO:0019543""(propionate catabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0042594""(response to starvation)|go:""GO:0046327""(glycerol biosynthetic process from pyruvate)|go:""GO:0070365""(hepatocyte differentiation)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|interpro:IPR008209(Phosphoenolpyruvate carboxykinase, GTP-utilising)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR018091|interpro:IPR035077|interpro:IPR035078|mint:Q16822|reactome:R-HSA-70263|refseq:NP_001018083.2|refseq:NP_001278485.1|refseq:NP_001294983.1|refseq:NP_004554.3|efo:""Orphanet:2880""|panther:PTHR11561(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0gMsJg2ASyOuH6uV9yRb1d4bMGk632	rogid:gbQbu8+tVa1xs/fKesefSJlpSaM9606	intact-crc:C4A17C810267C07A|rigid:Bpq05Ftl0lCfe4h+/EtbdZVpFLs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D008	uniprotkb:Q6ZSS7	intact:EBI-2841189|uniprotkb:Q74WC8	intact:EBI-2858252|uniprotkb:Q9NXM3|uniprotkb:D3KSZ4|uniprotkb:Q86TH2|ensembl:ENSP00000281416.7|ensembl:ENSP00000376141.1	psi-mi:q8d008_yerpe(display_long)|uniprotkb:livM2(gene name)|psi-mi:livM2(display_short)|uniprotkb:YP_0948(locus name)|uniprotkb:y3001(locus name)	psi-mi:mfsd6_human(display_long)|uniprotkb:MFSD6(gene name)|psi-mi:MFSD6(display_short)|uniprotkb:MMR2(gene name synonym)|uniprotkb:Macrophage MHC class I receptor 2 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858258|imex:IM-13779-6288	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|interpro:IPR017779(ABC transporter, urea, permease protein, UrtB)|interpro:IPR016024(Armadillo-type fold)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR052157"	"refseq:XP_011509670.1|refseq:NP_060164.3|refseq:XP_005246711.1|ensembl:ENSG00000151690.15(gene)|ensembl:ENST00000281416.11(transcript)|ensembl:ENST00000392328.6(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|interpro:IPR024989|interpro:IPR036259|interpro:IPR051717|panther:PTHR16172(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:f8uYuwhgruoNpYu1MdwJpc91v5Q632	rogid:Fu3jyjX1ribBg4Uq5gMo7qWRUbk9606	intact-crc:6C6883D5EEA50C7D|rigid:eHWXd7qranvotzgJHBWWLrM+Bj0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D054	uniprotkb:P52569	intact:EBI-2852052	intact:EBI-2858278|uniprotkb:O15291|uniprotkb:Q6NSZ7|uniprotkb:O15292|uniprotkb:Q14CQ6|uniprotkb:B7ZL54|uniprotkb:Q86TC6|ensembl:ENSP00000419140.2|ensembl:ENSP00000430464.1|ensembl:ENSP00000492016.2	psi-mi:q8d054_yerpe(display_long)|uniprotkb:fabF(gene name)|psi-mi:fabF(display_short)|uniprotkb:fabF_4(gene name synonym)|uniprotkb:NCTC5923_01694(orf name)|uniprotkb:y2744(locus name)	psi-mi:ctr2_human(display_long)|uniprotkb:SLC7A2(gene name)|psi-mi:SLC7A2(display_short)|uniprotkb:ATRC2(gene name synonym)|uniprotkb:CAT2(gene name synonym)|uniprotkb:Solute carrier family 7 member 2(gene name synonym)|uniprotkb:Low affinity cationic amino acid transporter 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858288|imex:IM-13779-6291	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018201|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016039(Thiolase-like)|interpro:IPR020841|go:""GO:0004315""(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:""GO:0006633""(fatty acid biosynthetic process)|interpro:IPR000794(Beta-ketoacyl synthase)"	"refseq:NP_001008539.3|refseq:NP_001158243.1|refseq:NP_003037.4|refseq:XP_005273667.1|refseq:XP_005273668.1|refseq:XP_005273669.1|ensembl:ENSG00000003989.18(gene)|ensembl:ENST00000494857.6(transcript)|ensembl:ENST00000522656.5(transcript)|ensembl:ENST00000640220.1(transcript)|go:""GO:0000064""(L-ornithine transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015174""(basic amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015189""(L-lysine transmembrane transporter activity)|go:""GO:0015807""(L-amino acid transport)|go:""GO:0030054""(cell junction)|go:""GO:0061459""(L-arginine transmembrane transporter activity)|go:""GO:0089718""(amino acid import across plasma membrane)|go:""GO:0097638""(L-arginine import across plasma membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1902475""(L-alpha-amino acid transmembrane transport)|go:""GO:1903352""(L-ornithine transmembrane transport)|go:""GO:1903826""(L-arginine transmembrane transport)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004755(Cationic amino acid transport permease)|interpro:IPR029485|mint:P52569|reactome:R-HSA-352230|refseq:XP_016869235.1|refseq:XP_016869236.1|panther:PTHR43243(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xl43YLev9BwgHiphq3Wzri47FxA632	rogid:sTEceBwq7KUpaNgBKVX2+ss/oKU9606	intact-crc:C8DF50AF123CEB8F|rigid:8ZZXWpetrP15oIbgL677n4CO9Ig	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A7Y8RCW6	uniprotkb:Q86TA5	intact:EBI-2845056|uniprotkb:Q7CKM5|uniprotkb:A0A5P8YBL8|uniprotkb:Q0WJU7	intact:EBI-2858302	psi-mi:a0a7y8rcw6_yerpe(display_long)|uniprotkb:YPO0363(locus name)	psi-mi:q86ta5_human(display_long)|uniprotkb:DKFZp451L0319(gene name)|psi-mi:DKFZp451L0319(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858310|imex:IM-13779-6292	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR024393|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR011066(Mechanosensitive ion channel MscS, C-terminal)|interpro:IPR006685(Mechanosensitive ion channel MscS)|interpro:IPR011014(Mechanosensitive ion channel MscS, transmembrane-2)|interpro:IPR006686(Mechanosensitive ion channel MscS, conserved site)|interpro:IPR025692|go:""GO:0005886""(plasma membrane)|go:""GO:0008381""(mechanosensitive monoatomic ion channel activity)|interpro:IPR049142|interpro:IPR049278|interpro:IPR023408|refseq:YP_002345441.1|interpro:IPR052702"	"refseq:NP_001036066.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|go:""GO:0003676""(nucleic acid binding)|interpro:IPR039190"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:z6l0v0GxSQqbhV/esC/hffWqLG8632	rogid:5HqsxsSaI6UfY6CyWXUMTrWmB4A9606	intact-crc:3BC986335CC32457|rigid:YzF7xLU1/6h58OekLkJSlUYNV0I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86TA5	uniprotkb:Q8CZU0	intact:EBI-2858302	intact:EBI-2858298	psi-mi:q86ta5_human(display_long)|uniprotkb:DKFZp451L0319(gene name)|psi-mi:DKFZp451L0319(display_short)	psi-mi:q8czu0_yerpe(display_long)|uniprotkb:ppsA_1(gene name)|psi-mi:ppsA_1(display_short)|uniprotkb:NCTC5923_02141(orf name)|uniprotkb:y3406(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858295|imex:IM-13779-6294	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001036066.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|go:""GO:0003676""(nucleic acid binding)|interpro:IPR039190"	"interpro:IPR020806|interpro:IPR020841|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR018201|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016039(Thiolase-like)|interpro:IPR050091|refseq:WP_002211631.1|go:""GO:0004315""(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0031177""(phosphopantetheine binding)|interpro:IPR036736|interpro:IPR042099|interpro:IPR040097|interpro:IPR045851"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5HqsxsSaI6UfY6CyWXUMTrWmB4A9606	rogid:FMVvuiYqaklkRdVMtBPUDzm55VU632	intact-crc:94DC9537C60A6204|rigid:2lraYLOi3xh/si+3bY3r2ce0qGU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WJF8	uniprotkb:Q86TA5	intact:EBI-2840848|uniprotkb:Q74Q40|uniprotkb:A0A384KWW8|uniprotkb:A0A0H2W7R8|uniprotkb:Q7CG97	intact:EBI-2858302	psi-mi:q0wjf8_yerpe(display_long)|uniprotkb:YPO0507(locus name)	psi-mi:q86ta5_human(display_long)|uniprotkb:DKFZp451L0319(gene name)|psi-mi:DKFZp451L0319(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858317|imex:IM-13779-6293	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|refseq:YP_002345580.1|refseq:WP_002210474.1|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)|interpro:IPR050708|panther:PTHR32305(orthology-group)	"refseq:NP_001036066.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|go:""GO:0003676""(nucleic acid binding)|interpro:IPR039190"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JSZl/NaLilra6W552YbRdX1LvXc632	rogid:5HqsxsSaI6UfY6CyWXUMTrWmB4A9606	intact-crc:3912E3D99F1F54F8|rigid:UFqRRw0Boxe0xEunBGJcRj5ls88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8ZIC5	-	intact:EBI-2858331|uniprotkb:Q0WJ86	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:uxab_yerpe(display_long)|uniprotkb:uxaB(gene name)|psi-mi:uxaB(display_short)|uniprotkb:Tagaturonate dehydrogenase(gene name synonym)|uniprotkb:Tagaturonate reductase(gene name synonym)|uniprotkb:YPO0580(locus name)|uniprotkb:y3599(locus name)|uniprotkb:YP_2900(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858336|imex:IM-13779-6297	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR023668|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR013118(Mannitol dehydrogenase, C-terminal)|interpro:IPR013131(Mannitol dehydrogenase, N-terminal)|refseq:WP_002210409.1|go:""GO:0005829""(cytosol)|go:""GO:0008926""(mannitol-1-phosphate 5-dehydrogenase activity)|go:""GO:0009026""(tagaturonate reductase activity)|go:""GO:0019592""(mannitol catabolic process)|go:""GO:0019698""(D-galacturonate catabolic process)|interpro:IPR036291|refseq:YP_002345652.1|panther:PTHR30524(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:PyqKR9KbcVlhb9JsQra1Qvptw6Y632	intact-crc:4AC01DA7E95342A7|rigid:FZl8ExUoif6G+LzaYnG1g82F5pE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZDF8	intact:EBI-1033611	intact:EBI-2843052|uniprotkb:Q0WDS2	-	psi-mi:syl_yerpe(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO2610(locus name)|uniprotkb:YP_1103(locus name)|uniprotkb:y1184(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858343|imex:IM-13779-6298	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR025709|interpro:IPR015413(""Aminoacyl-tRNA synthetase, class I (M)"")|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004823""(leucine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006429""(leucyl-tRNA aminoacylation)|refseq:WP_002210333.1|refseq:YP_002347566.1|panther:PTHR43740(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3sEWdGj2m6kDFCDXlrNdwz7rjRs632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:3A3620A7EA9A973A|rigid:ZvJNQeIImc/P0c/oU4qnW7St2I8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8ZD36	-	intact:EBI-2853182|uniprotkb:Q0WDD5|intact:EBI-2862751	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:mnmc_yerpe(display_long)|uniprotkb:mnmC(gene name)|psi-mi:mnmC(display_short)|uniprotkb:YPO2756(locus name)|uniprotkb:y1590(locus name)|uniprotkb:YP_2407(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858324|imex:IM-13779-6295	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR029063|interpro:IPR008471(Protein of unknown function DUF752)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR023032|interpro:IPR017610(tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal)|rcsb pdb:3PVC|rcsb pdb:3SGL|refseq:WP_002209716.1|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0004808""(""tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0016645""(oxidoreductase activity, acting on the CH-NH group of donors)|go:""GO:0032259""(methylation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR047785|interpro:IPR036188|refseq:YP_002347703.1|panther:PTHR13847(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:WUUEfp2U7AMQZl+RUxlKHTdbp3E632	intact-crc:A7D320A7E9A4B0CD|rigid:VocxSCFcotesScxmgCMK0VdexIA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A3G5LAS3	-	intact:EBI-2858353|uniprotkb:A0A1U8QWA8|uniprotkb:Q74YJ3|uniprotkb:Q9ZGY3|uniprotkb:Q7ARA8|uniprotkb:A0A0H2W1Z2|uniprotkb:A0A384LAQ1	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a3g5las3_yerpe(display_long)|uniprotkb:YPMT1.86c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858350|imex:IM-13779-6296	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	refseq:NP_395432.1|refseq:WP_002228802.1	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:7tH07Yv4XPfqK+U1ZykbkUm6Uuk632	intact-crc:C827052DFC16C718|rigid:cA4eGFfEdmAkuniDPhTcEtkUhuQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8D0F7	-	intact:EBI-2858387|uniprotkb:Q74U34	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:q8d0f7_yerpe(display_long)|uniprotkb:YP_1918(locus name)|uniprotkb:rnd(gene name)|psi-mi:rnd(display_short)|uniprotkb:y2235(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858392|imex:IM-13779-6301	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR002562(3'-5' exonuclease)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR010997(HRDC-like)|interpro:IPR006292(Ribonuclease D)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR051086|go:""GO:0000166""(nucleotide binding)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0033890""(ribonuclease D activity)|go:""GO:0042780""(tRNA 3'-end processing)|interpro:IPR036397|interpro:IPR048579|interpro:IPR044876"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:uepiYyTWB1eAu/pzLVjmyvmm7/w632	intact-crc:BDA14719E9EB831A|rigid:5hX7yjpeqG1fBbFsRhY8MAqsUvw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1R0	intact:EBI-1033611	intact:EBI-2843803	-	psi-mi:q8d1r0_yerpe(display_long)|uniprotkb:degQ(gene name)|psi-mi:degQ(display_short)|uniprotkb:y0137(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858361|imex:IM-13779-6299	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|interpro:IPR036034"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AA9pxma2K+wssT66h3sgiRuf6Uc632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:18A83619E879C322|rigid:12RToUJ0EuqeR9vYxC6E6dbXRzw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8D131	-	intact:EBI-2858378|uniprotkb:Q74VY8	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:q8d131_yerpe(display_long)|uniprotkb:mviM1(gene name)|psi-mi:mviM1(display_short)|uniprotkb:YP_1131(locus name)|uniprotkb:y1152(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858375|imex:IM-13779-6300	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR050463|go:""GO:0000166""(nucleotide binding)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR055170|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:A5TCBtioM6Hbyj2QQ+aVDQPo8D8632	intact-crc:68993619E8325F7A|rigid:kMr3i0V5GTKd6hE01gnF5DSBpco	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8D176	-	intact:EBI-2842041	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:q8d176_yerpe(display_long)|uniprotkb:y0939(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858368|imex:IM-13779-6302	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR010158(Amidase, hydantoinase/carbamoylase)|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|go:""GO:0016813""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"")|go:""GO:0046872""(metal ion binding)|interpro:IPR036264"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:/GOJxJQAHqgWtVu6otA2a4TvHfI632	intact-crc:9A5D3619E9A5D0E9|rigid:pvhuOuzYwhbBybV1brH4lMNRGNI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0E1	intact:EBI-1033611	intact:EBI-2851171	-	psi-mi:q8d0e1_yerpe(display_long)|uniprotkb:y2338(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858399|imex:IM-13779-6303	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR010252(Formiminoglutamate deiminase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR032466|go:""GO:0016810""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"")|interpro:IPR051607"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PERKzynzhTOYlkTaHwhsilRxm0U632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:5C324719E821650C|rigid:oLgexrKeLjPHEWDakcC1YeF/ikA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8CZU0	-	intact:EBI-2858298	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:q8czu0_yerpe(display_long)|uniprotkb:ppsA_1(gene name)|psi-mi:ppsA_1(display_short)|uniprotkb:NCTC5923_02141(orf name)|uniprotkb:y3406(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858420|imex:IM-13779-6305	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR020806|interpro:IPR020841|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR018201|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016039(Thiolase-like)|interpro:IPR050091|refseq:WP_002211631.1|go:""GO:0004315""(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0031177""(phosphopantetheine binding)|interpro:IPR036736|interpro:IPR042099|interpro:IPR040097|interpro:IPR045851"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:FMVvuiYqaklkRdVMtBPUDzm55VU632	intact-crc:BC1D7F4EE87840E2|rigid:yG0mi+xn9E/KwE9j4sGUAH5YfYo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A6B3V8I0	-	intact:EBI-2858430	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a6b3v8i0_yerpe(display_long)|uniprotkb:y3432(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858427|imex:IM-13779-6307	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	uniprotkb:A0A6B3T871(uniprot-removed-ac)|interpro:IPR031325|interpro:IPR001826(RHS protein)|interpro:IPR006530(YD repeat)|interpro:IPR022385|interpro:IPR050708|interpro:IPR045351|refseq:WP_002223678.1	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:15j6ruoytaqTYCE9CNBDSnL94j8632	intact-crc:12C14684E1E9F22D|rigid:xSO5MtxGxfu7e8NQG8eswH5hAlo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZZ7	intact:EBI-1033611	intact:EBI-2842831|uniprotkb:Q74W48	-	psi-mi:q8czz7_yerpe(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:YP_1051(locus name)|uniprotkb:y3075(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858406|imex:IM-13779-6306	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5D57QZRbHjtu2izZZ+54f7spmuk632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:22C27F4EE9EDCD8B|rigid:4jvf3iI7AThqm5/EKueA7V1GayI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8CZX8	-	intact:EBI-2842787|uniprotkb:Q74S00	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:q8czx8_yerpe(display_long)|uniprotkb:lysR(gene name)|psi-mi:lysR(display_short)|uniprotkb:lysR17(gene name synonym)|uniprotkb:YP_2860(locus name)|uniprotkb:y3185(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858413|imex:IM-13779-6304	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:EsQj+JSnKznEgjvjnq0+lLlaUlg632	intact-crc:17207F4EEA9C73D0|rigid:yA8p0yf7eFDkBt+oQRqlvDi72OM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8CLU1	-	intact:EBI-2858457|uniprotkb:Q74PI9	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:q8clu1_yerpe(display_long)|uniprotkb:YP_3916(locus name)|uniprotkb:y0237(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858461|imex:IM-13779-6311	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	-	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:0uc/wKxOf6SolN7v6B1IoBBJqMM632	intact-crc:6205494EE824BB9E|rigid:6ElI86a45W/TZ7Z0IV8NxzibQ+8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A6B3VBG4	-	intact:EBI-2852922	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a6b3vbg4_yerpe(display_long)|uniprotkb:y3441(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858438|imex:IM-13779-6312	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR042187|uniprotkb:A0A6B3T508(uniprot-removed-ac)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009288""(bacterial-type flagellum)|refseq:WP_002223682.1|interpro:IPR046358"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:lSNXlJTIub0W1CW9Z3nGnfxHIa0632	intact-crc:3FB57C84E099329E|rigid:jhvWpd2pG13IK2gihQ/xmKG0DZU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A0H2W4H3	-	intact:EBI-2858468	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a0h2w4h3_yerpe(display_long)|uniprotkb:YP_1837(locus name)|uniprotkb:y2321(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858472|imex:IM-13779-6309	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"uniprotkb:A0A6B3T4U9(uniprot-removed-ac)|interpro:IPR006597(Sel1-like)|interpro:IPR025115|go:""GO:0016020""(membrane)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_002224461.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:NVXO5Rz08tT/PDCoVtWWQlxThz0632	intact-crc:E581190523A98ACD|rigid:J+FYbO7D5rud0Q752EmPBIfRUKU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q74PW2	-	intact:EBI-2858445|uniprotkb:Q8CZM9	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:lsrb_yerpe(display_long)|uniprotkb:lsrB(gene name)|psi-mi:lsrB(display_short)|uniprotkb:YPO0409(locus name)|uniprotkb:y3772(locus name)|uniprotkb:YP_3772(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858450|imex:IM-13779-6308	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR028082|rcsb pdb:3T95|interpro:IPR025997|interpro:IPR050555|interpro:IPR030159|refseq:WP_002209189.1|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|refseq:YP_002345486.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:HwGPUMANnHZjBVvIO9NkzMLorcQ632	intact-crc:FE3638B037C105A3|rigid:O/cSgcD6wLpUqJqiZWt/qlrkNhk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A2U2GXV0	-	intact:EBI-2840495|uniprotkb:Q74PJ9|uniprotkb:A0A0H2W8W4|uniprotkb:A0A384L2Q0|uniprotkb:Q7CL55	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a2u2gxv0_yerpe(display_long)|uniprotkb:YPO3641(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858479|imex:IM-13779-6310	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	refseq:WP_002210051.1|refseq:YP_002348526.1|interpro:IPR036869	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:SVf+9kCFQwgDlka34vEDmNYw9/Q632	intact-crc:5AF566F416DD9FE7|rigid:PFYkvvALvVuv+1YO2h0c/Dpfp1k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A5P8YJI1	-	intact:EBI-2858529|uniprotkb:Q0WDU9|uniprotkb:Q74VY7|uniprotkb:Q7CJW5|uniprotkb:A0A0H2W3R2|uniprotkb:A0A384L3Q2	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a5p8yji1_yerpe(display_long)|uniprotkb:YPO2583(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858526|imex:IM-13779-6315	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR001851(Bacterial inner-membrane translocator)|refseq:WP_002210302.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:YP_002347539.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:FHy7gYcL9rb0sZLs/qmTFUaBQFA632	intact-crc:BB20CEFEE6208C1E|rigid:ejdFMeUw8wjC4dzxZ8AW/P92bjM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H195	intact:EBI-1033611	intact:EBI-2856351|uniprotkb:Q0WK20|uniprotkb:A0A3N4B003|uniprotkb:Q7CKR0|uniprotkb:A0A384LAZ5	-	psi-mi:a0a2u2h195_yerpe(display_long)|uniprotkb:YPO0286(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858498|imex:IM-13779-6316	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002209066.1|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR026332|interpro:IPR034505|go:""GO:0003824""(catalytic activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051536""(iron-sulfur cluster binding)|refseq:YP_002345368.1"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Li7e0B3DlkLENa113dhTD5393Po632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:DBB4262B17E6C625|rigid:wdnyQZUuo2csTp001dOG58iLpCU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A5P8YAT7	-	intact:EBI-2858489|uniprotkb:Q0WA98|uniprotkb:Q74RC8|uniprotkb:Q7CL10|uniprotkb:A0A2U2GZF0|uniprotkb:A0A384KAR2	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a5p8yat7_yerpe(display_long)|uniprotkb:oxyR(gene name)|psi-mi:oxyR(display_short)|uniprotkb:YPO3915(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858486|imex:IM-13779-6313	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|refseq:WP_002209478.1|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|refseq:YP_002348790.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:0KxIjKerk7G+ruNiISO3pEw7LQY632	intact-crc:AE81D5FEE7EC8A05|rigid:gN338rUBOcFdYa/4Ay+GkEkojoc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A2S9PJM4	-	intact:EBI-2845974|uniprotkb:Q74XF1|uniprotkb:Q7CKP1|uniprotkb:A0A3N4B1T8|uniprotkb:A0A0H2W2H9	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a2s9pjm4_yerpe(display_long)|uniprotkb:tyrB(gene name)|psi-mi:tyrB(display_short)|uniprotkb:YPO0322(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858505|imex:IM-13779-6314	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|refseq:WP_002209097.1|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:YP_002345402.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:gUXDGn5QEZOQcHwUvev80Fg2l8s632	intact-crc:31CEACDDC38FAA7D|rigid:4Uh+Rx+9AmkATUOeJ7xwNsh9gN4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H1T2	intact:EBI-1033611	intact:EBI-2847930|uniprotkb:A0A380PGD9|uniprotkb:Q0WBW0|uniprotkb:Q7CKB2|uniprotkb:A0A384KAJ5	-	psi-mi:a0a2u2h1t2_yerpe(display_long)|uniprotkb:YPO3332(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858519|imex:IM-13779-6318	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|refseq:WP_002216010.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:YP_002348228.1"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pJcJoiSi0mBqBQjt8m5FB8UHoDE632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:A3C9262B1664CD6C|rigid:Iqz9Otm3lTHF3K7D45O0fHCc10M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W2N9	intact:EBI-1033611	intact:EBI-2840467|uniprotkb:Q74XT4|uniprotkb:Q0WBR4|uniprotkb:A0A384L498|uniprotkb:Q7CKD3|uniprotkb:A0A3N4B9W7	-	psi-mi:a0a0h2w2n9_yerpe(display_long)|uniprotkb:degP(gene name)|psi-mi:degP(display_short)|uniprotkb:gsrA(gene name synonym)|uniprotkb:htrA(gene name synonym)|uniprotkb:ptd(gene name synonym)|uniprotkb:YPO3382(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858512|imex:IM-13779-6317	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:WP_002209370.1|refseq:YP_002348274.1|interpro:IPR036034"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wh5TqHAdstARdvvFDyS2kqzSnxY632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:A2683F0521F6443D|rigid:bZ+VVvUPCyyRGgL6tZfRxDqtygc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYS8	intact:EBI-1033611	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	-	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858564|imex:IM-13779-6321	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:DA9D17F4143B4B72|rigid:yDrzCgZTNendU1w2DvyODcr2d0A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YES8	intact:EBI-1033611	intact:EBI-2848652|uniprotkb:Q74US7|uniprotkb:A0A0H2W5A9|uniprotkb:Q7CHW1|uniprotkb:A0A384KDB2	-	psi-mi:a0a5p8yes8_yerpe(display_long)|uniprotkb:sdaA(gene name)|psi-mi:sdaA(display_short)|uniprotkb:YPO1771(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858571|imex:IM-13779-6323	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029009|interpro:IPR004644(Iron-sulphur-dependent L-serine dehydratase single chain form)|interpro:IPR005130(Serine dehydratase alpha chain)|interpro:IPR005131(Serine dehydratase beta chain)|refseq:WP_002211079.1|go:""GO:0003941""(L-serine ammonia-lyase activity)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:YP_002346768.1|interpro:IPR051318|panther:PTHR30182(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yVnD/73Ksx+jEUDkJwTGNlx1tGM632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:C0A311FEE49C1A2F|rigid:Fp+N+dsBhZFiXsZ7gfnZiSQovds	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A5P8YGH4	-	intact:EBI-2842137|uniprotkb:Q0WF29|uniprotkb:Q7CIG0	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a5p8ygh4_yerpe(display_long)|uniprotkb:YPO2131(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858557|imex:IM-13779-6320	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	interpro:IPR015406(Protein of unknown function DUF1983)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032876|refseq:WP_002211698.1|interpro:IPR036116|refseq:YP_002347109.1|interpro:IPR053171|panther:PTHR36251(orthology-group)	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:oOCFMN5J0JyZf3JZhYlAIr4sCxM632	intact-crc:9612F3FEE70FD1B5|rigid:WPyY4GHAiQKodbXYxnks8N4oK+g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A380PDY1	-	intact:EBI-2848416|uniprotkb:Q74UI0|uniprotkb:A0A0H2W558|uniprotkb:Q7CIW0|uniprotkb:A0A384L8E0	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a380pdy1_yerpe(display_long)|uniprotkb:ogl(gene name)|psi-mi:ogl(display_short)|uniprotkb:YPO1713(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858538|imex:IM-13779-6319	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027946|refseq:WP_002210841.1|go:""GO:0045490""(pectin catabolic process)|go:""GO:0047487""(oligogalacturonide lyase activity)|refseq:YP_002346716.1|panther:PTHR36842(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:e8mn+xTHxqbWMCnpEvzfGUD7MYI632	intact-crc:11B803573B2266C6|rigid:4EmHojgIaGtxBADzt2kRhUBYg2E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PDG1	intact:EBI-1033611	intact:EBI-2858548|uniprotkb:Q74TV6|uniprotkb:Q7CIL5|uniprotkb:A0A0H2W529	-	psi-mi:a0a380pdg1_yerpe(display_long)|uniprotkb:acn(gene name)|psi-mi:acn(display_short)|uniprotkb:acnA(gene name synonym)|uniprotkb:YPO2221(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858545|imex:IM-13779-6322	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044137|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR018136|refseq:WP_002215187.1|go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006101""(citrate metabolic process)|go:""GO:0030350""(iron-responsive element binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR036008|refseq:YP_002347193.1|panther:PTHR11670(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:U+Apr4nPvMOLOKyPanMpXDngrWk632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:720603573B2484C9|rigid:nv8pnaim4LF5ELVWEAgvN+F5ZZw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A0H2W496	-	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858592|imex:IM-13779-6325	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	intact-crc:E6A0190522942487|rigid:n6nSx6Wc050B0GZ9i0z15bzBZzM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A3N4B3A1	-	intact:EBI-2846733|uniprotkb:Q74VL0|uniprotkb:A0A0H2W474|uniprotkb:Q7CHE8|uniprotkb:A0A384KI85	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a3n4b3a1_yerpe(display_long)|uniprotkb:fpr(gene name)|psi-mi:fpr(display_short)|uniprotkb:fruB(gene name synonym)|uniprotkb:fruF(gene name synonym)|uniprotkb:YPO1298(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858585|imex:IM-13779-6324	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR002114(Phosphotransferase system, HPr serine phosphorylation site)|refseq:WP_002208799.1|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0090563""(protein-phosphocysteine-sugar phosphotransferase activity)|interpro:IPR035895|refseq:YP_002346323.1|interpro:IPR050893|panther:PTHR30181(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:Vp2FIu9BGFwhpfjQL30qgAgLZPU632	intact-crc:80FFD908BB535DA9|rigid:6yzJI1IcdP/Bq3pWgaKjZ7bjLWo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PIH8	intact:EBI-1033611	intact:EBI-2845089|uniprotkb:Q74RZ9|uniprotkb:Q0WIN7|uniprotkb:Q7CGZ1|uniprotkb:A0A384KV76	-	psi-mi:a0a2s9pih8_yerpe(display_long)|uniprotkb:lysA(gene name)|psi-mi:lysA(display_short)|uniprotkb:YPO0796(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858599|imex:IM-13779-6327	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR002986(Diaminopimelate decarboxylase)|interpro:IPR022643|interpro:IPR022644|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|interpro:IPR022653|interpro:IPR022657|interpro:IPR029066|go:""GO:0008836""(diaminopimelate decarboxylase activity)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:WP_002209846.1|refseq:YP_002345851.1|panther:PTHR43727(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PVmk2FT176nUnOdaH1n3olLPC7Q632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:941C3FDDC01A83B4|rigid:sV7qV+xWgfMknkF7YqwEfU+0rSY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A2U2H160	-	intact:EBI-2839804|uniprotkb:Q74VL9|uniprotkb:Q0WHA0|uniprotkb:Q7CHF5|uniprotkb:A0A384KFZ8|uniprotkb:A0A5P8YDY1	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a2u2h160_yerpe(display_long)|uniprotkb:YPO1313(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858578|imex:IM-13779-6326	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|refseq:WP_002208782.1|interpro:IPR010916(TonB box, conserved site)|go:""GO:0009279""(cell outer membrane)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002346338.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:Mg0owqCn0ozvLrRu4vW8Rgc4sZk632	intact-crc:C76B262B16CAB5BE|rigid:A4wW6Kmnr50vz6Ho3OhUKqzUgcg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WJ53	intact:EBI-1033611	intact:EBI-2841146|uniprotkb:A0A0H2W7L9|uniprotkb:Q74RT3|uniprotkb:Q7CGF0|uniprotkb:A0A380PMR6	-	psi-mi:q0wj53_yerpe(display_long)|uniprotkb:YPO0616(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858627|imex:IM-13779-6329	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002345685.1|interpro:IPR002772(Glycoside hydrolase, family 3, C-terminal)|interpro:IPR001764(Glycoside hydrolase, family 3, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR026891|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036881|interpro:IPR036962|refseq:WP_002210379.1|interpro:IPR051915"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NIeb7qLRqloPp0rZ/Uu04q0TwMU632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:63224B71608A7B7C|rigid:QnEeEI0dXPHaIOACmLSyYwTtXBE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A380PLQ4	-	intact:EBI-2841937|uniprotkb:Q74RN6|uniprotkb:Q7CGH9|uniprotkb:A0A0H2W839	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a380plq4_yerpe(display_long)|uniprotkb:parC(gene name)|psi-mi:parC(display_short)|uniprotkb:Topoisomerase IV subunit A(gene name synonym)|uniprotkb:YPO0671(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858620|imex:IM-13779-6331	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006265""(DNA topological change)|go:""GO:0007059""(chromosome segregation)|go:""GO:0009330""(""DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex"")|go:""GO:0019897""(extrinsic component of plasma membrane)|go:""GO:0034335""(DNA negative supercoiling activity)|refseq:WP_002212178.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR035516|interpro:IPR005742(DNA topoisomerase IV, subunit A, Gram-negative)|refseq:YP_002345739.1|interpro:IPR050220|panther:PTHR43493(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:IvRCQJ0mieNBBTNb7i1F6inwn/8632	intact-crc:C9DB8B573A0F8146|rigid:eq8aglCkEFwb6WcU3Gmj2RPUolU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CGB6	intact:EBI-1033611	intact:EBI-2846518|uniprotkb:Q74Q78	-	psi-mi:seca_yerpe(display_long)|uniprotkb:secA(gene name)|psi-mi:secA(display_short)|uniprotkb:YPO0564(locus name)|uniprotkb:y3617(locus name)|uniprotkb:YP_3620(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858634|imex:IM-13779-6330	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004027(SEC-C motif)|interpro:IPR000185(SecA protein)|interpro:IPR020937|interpro:IPR011115(SecA DEAD-like)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR044722|interpro:IPR027417|refseq:WP_002210426.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0017038""(protein import)|go:""GO:0031522""(cell envelope Sec protein transport complex)|go:""GO:0043952""(protein transport by the Sec complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0065002""(intracellular protein transmembrane transport)|interpro:IPR036266|interpro:IPR036670|refseq:YP_002345635.1|panther:PTHR30612(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3yL6/B2I1wIRUb5RFvMibkWeWlQ632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:155EE6B736B61CF9|rigid:JGX/TicvoGOQOkMO4/1ErWf1dNI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q0WIJ7	-	intact:EBI-2851185|uniprotkb:Q74QE7|uniprotkb:A0A0H2W874|uniprotkb:A0A3N4B4F6|uniprotkb:Q7CGW9|uniprotkb:A0A384LBF7	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:q0wij7_yerpe(display_long)|uniprotkb:YPO0840(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858606|imex:IM-13779-6332	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010905(Glycosyl hydrolase, family 88)|refseq:WP_002209884.1|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR012341(Six-hairpin glycosidase)|refseq:YP_002345891.1|interpro:IPR052043"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:OJNnsHqKxXDsmBDCvDpKtYoti2k632	intact-crc:84CAD87161E80752|rigid:o3rRPOFhhd0CRwNQI1id1i9R1w4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A2S9PFM0	-	intact:EBI-2846871|uniprotkb:Q74QH1|uniprotkb:A0A0H2W7H4|uniprotkb:Q7CGR9|uniprotkb:A0A384LFS9	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a2s9pfm0_yerpe(display_long)|uniprotkb:YPO0938(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858613|imex:IM-13779-6328	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR017755(N-carbamoylputrescine amidase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:WP_002209979.1|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0050126""(N-carbamoylputrescine amidase activity)|interpro:IPR036526|refseq:YP_002345985.1|interpro:IPR050345"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:VEt5ZICBEzJqD2dQaZCgWKgplSI632	intact-crc:8050E0DDC2FC540C|rigid:kXv+oVzqkQfqGg0IEfUUGrXqWw8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q7ARH3	-	intact:EBI-2849426|uniprotkb:A0A384KLR8|uniprotkb:O68711|uniprotkb:Q74YV0|uniprotkb:A0A0H2W092|uniprotkb:A0A2U2GVE2	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:q7arh3_yerpe(display_long)|uniprotkb:tnpA(gene name)|psi-mi:tnpA(display_short)|uniprotkb:YPCD1.90c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858673|imex:IM-13779-6337	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"refseq:NP_857769.1|interpro:IPR002513(Transposase, Tn3)|refseq:NP_395219.1|interpro:IPR025296|interpro:IPR047653|refseq:WP_002213256.1|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:00nBYkSaVEOjkb6Bm6Lk/llhQRc632	intact-crc:A6EAF955379B4480|rigid:Rkt0oZPS8gCWqjHr7aSN5jbkRn0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YMT8	intact:EBI-1033611	intact:EBI-2858655|uniprotkb:A0A1U8QPA8|uniprotkb:O68748|uniprotkb:Q74YN5|uniprotkb:Q7ARE3|uniprotkb:A0A384L3Y0	-	psi-mi:a0a5p8ymt8_yerpe(display_long)|uniprotkb:YPMT1.30(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858659|imex:IM-13779-6334	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_395368.1|interpro:IPR027417|interpro:IPR050615|refseq:WP_002211794.1|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|panther:PTHR11274(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BJmupnbfQIWjfKKF1hJ9rDPFilY632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:041F99FEE49D8E34|rigid:GyJRLRZzId3TvMKo/+MGAyylnmo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYH3	intact:EBI-1033611	intact:EBI-2842340|uniprotkb:Q74PE3|uniprotkb:Q0W9X2|uniprotkb:Q7CFQ3|uniprotkb:A0A5P8YAI4|uniprotkb:A0A384L096	-	psi-mi:a0a2u2gyh3_yerpe(display_long)|uniprotkb:fdoH(gene name)|psi-mi:fdoH(display_short)|uniprotkb:YPO4057(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858648|imex:IM-13779-6336	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR006470(Formate dehydrogenase, beta subunit)|interpro:IPR014603(Formate dehydrogenase, iron-sulphur subunit)|interpro:IPR015246(Formate dehydrogenase, transmembrane)|interpro:IPR017900|go:""GO:0005886""(plasma membrane)|go:""GO:0015944""(formate oxidation)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002209611.1|interpro:IPR038384|refseq:YP_002348916.1|interpro:IPR051555"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qUnsGukyBMEHq2jL5PYOvQ0betE632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:6A9617F4163E7C3F|rigid:6BNJOzra4ALNzK0PhM3qmOSLbK0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H129	intact:EBI-1033611	intact:EBI-2842176|uniprotkb:Q7ARE9|uniprotkb:A0A1U8QLB5|uniprotkb:O68740|uniprotkb:A0A384K8I4	-	psi-mi:a0a2u2h129_yerpe(display_long)|uniprotkb:YPMT1.23c(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858666|imex:IM-13779-6335	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395359.1	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4xa0lQiscvHi6CWXCiIT959GpQw632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:DBAF262B1470C2F1|rigid:Pcc9K4BKCzkCFS9iOEJrJ+GwxMY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A5P8YLY5	-	intact:EBI-2840998|uniprotkb:A0A384LAN6|uniprotkb:Q74Y20|uniprotkb:Q7CFW0|uniprotkb:Q0WKE1	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a5p8yly5_yerpe(display_long)|uniprotkb:nirB(gene name)|psi-mi:nirB(display_short)|uniprotkb:YPO0161(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858641|imex:IM-13779-6333	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"refseq:YP_002345247.1|interpro:IPR007419(BFD-like [2Fe-2S]-binding region)|interpro:IPR005117(Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like)|interpro:IPR012744(""Nitrite reductase [NAD(P)H] large subunit, NirB"")|interpro:IPR017121(""Nitrite reductase [NAD(P)H], large subunit"")|interpro:IPR006067(Nitrite and sulphite reductase 4Fe-4S region)|interpro:IPR006066(Nitrite and sulphite reductase iron-sulphur/siroheme-binding site)|interpro:IPR023753|interpro:IPR041575|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|go:""GO:0020037""(heme binding)|go:""GO:0042128""(nitrate assimilation)|go:""GO:0046872""(metal ion binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0050661""(NADP binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0098809""(nitrite reductase activity)|refseq:WP_002208886.1|interpro:IPR036136|interpro:IPR036188|interpro:IPR041854|interpro:IPR052034|interpro:IPR045854|panther:PTHR43809(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:6u3Rf93p+0SPTDFZ4PpmLjcphzY632	intact-crc:CAFFE8FEE756BFC6|rigid:DqsFeh3YNJJW2prSnFaCmC1NCBk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZH56	intact:EBI-1033611	intact:EBI-2858713|uniprotkb:Q0WHY9	-	psi-mi:lpxa_yerpe(display_long)|uniprotkb:lpxA(gene name)|psi-mi:lpxA(display_short)|uniprotkb:YPO1056(locus name)|uniprotkb:y3123(locus name)|uniprotkb:YP_2794(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858718|imex:IM-13779-6339	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR018357|interpro:IPR010137(Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029098|refseq:WP_002212143.1|go:""GO:0005737""(cytoplasm)|go:""GO:0008780""(acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0016020""(membrane)|interpro:IPR037157|refseq:YP_002346099.1|panther:PTHR43480(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FhCkLw4XLpgMGYyblPQ5lccpk24632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:BD6B6CA7E9A5795A|rigid:eF3Vg1h9n31ZKAt85B+eKhUHlp4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8ZFX5	-	intact:EBI-2851740|uniprotkb:Q0WGM4	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:hisx_yerpe(display_long)|uniprotkb:hisD(gene name)|psi-mi:hisD(display_short)|uniprotkb:YPO1548(locus name)|uniprotkb:y2621(locus name)|uniprotkb:YP_1437(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858725|imex:IM-13779-6340	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR001692(Histidinol dehydrogenase)|interpro:IPR022695|interpro:IPR012131(Histidinol dehydrogenase, prokaryotic)|refseq:WP_002211895.1|go:""GO:0000105""(L-histidine biosynthetic process)|go:""GO:0004399""(histidinol dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0051287""(NAD binding)|refseq:YP_002346564.1|panther:PTHR21256(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:aXT+/ioqFLvYG1ayljhfqLE1ikU632	intact-crc:E532C2A7E9548CDB|rigid:HyFe++Xf1U9WbD0+gWsz/bNEYRk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q7CJG3	-	intact:EBI-2844548|uniprotkb:Q74SH9	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:macb2_yerpe(display_long)|uniprotkb:macB2(gene name)|psi-mi:macB2(display_short)|uniprotkb:YPO3000(locus name)|uniprotkb:y1480(locus name)|uniprotkb:YP_2625(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858706|imex:IM-13779-6341	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|interpro:IPR027417|refseq:WP_002208496.1|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0046677""(response to antibiotic)|refseq:YP_002347924.1|interpro:IPR050250|panther:PTHR30572(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:qWvpFRqsQF+xx75wAFlSYA197R0632	intact-crc:BDA8DBB7379832AF|rigid:QJ9hTG57C4I3PPbz05pbrUdIFB0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAS8	intact:EBI-1033611	intact:EBI-2858695|uniprotkb:Q0WAU5|uniprotkb:Q74RG2|uniprotkb:Q7CLD6	-	psi-mi:malk_yerpe(display_long)|uniprotkb:malK(gene name)|psi-mi:malK(display_short)|uniprotkb:YPO3712(locus name)|uniprotkb:y0031(locus name)|uniprotkb:YP_3074(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858692|imex:IM-13779-6338	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR015855(ABC transporter, maltose/maltodextrin import, MalK)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR027417|interpro:IPR040582|refseq:WP_002212091.1|go:""GO:0005524""(ATP binding)|go:""GO:0015423""(ABC-type maltose transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055052""(""ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing"")|go:""GO:1990060""(maltose transport complex)|interpro:IPR047641|refseq:YP_002348593.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR43875(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iYvtpY6Sey6L+FCWA7ApyIW7S6Q632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:363B95A7EA9E76E0|rigid:t9Pxmz/44fHubHNoogCZmuXFm/c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q7CHF8	-	intact:EBI-2858680|uniprotkb:Q74VM4	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:metn2_yerpe(display_long)|uniprotkb:metN2(gene name)|psi-mi:metN2(display_short)|uniprotkb:YPO1318(locus name)|uniprotkb:y2866(locus name)|uniprotkb:YP_1274(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858685|imex:IM-13779-6342	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR018449|interpro:IPR027417|interpro:IPR050086|refseq:WP_002208776.1|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0033232""(ABC-type D-methionine transporter activity)|interpro:IPR041701|refseq:YP_002346343.1|interpro:IPR045865|panther:PTHR43166(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:KCSOYehf7X3uUPwm7zLeMXPOAdo632	intact-crc:7A6339B7359A94A9|rigid:em/y01LJI+HPc1XiEOGOboyTpK4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAN0	intact:EBI-1033611	intact:EBI-2842242|uniprotkb:Q0WAP3	-	psi-mi:fadb_yerpe(display_long)|uniprotkb:fadB(gene name)|psi-mi:fadB(display_short)|uniprotkb:YPO3766(locus name)|uniprotkb:y0464(locus name)|uniprotkb:YP_3282(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858746|imex:IM-13779-6344	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|interpro:IPR012799(Fatty oxidation complex, alpha subunit FadB)|interpro:IPR029045|go:""GO:0004165""(""delta(3)-delta(2)-enoyl-CoA isomerase activity"")|go:""GO:0004300""(enoyl-CoA hydratase activity)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0008692""(3-hydroxybutyryl-CoA epimerase activity)|go:""GO:0016509""(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0036125""(fatty acid beta-oxidation multienzyme complex)|go:""GO:0070403""(NAD+ binding)|refseq:WP_002211546.1|interpro:IPR036291|refseq:YP_002348645.1|interpro:IPR050136|panther:PTHR43612(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zUCGFSdEv7X+WT+PNMNgwgSM+4c632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:5A1695A7E87F8A25|rigid:h9gtpEX+RVUejmos05cUFlgejX0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8ZGX4	-	intact:EBI-2840069|uniprotkb:Q74W78|uniprotkb:Q0WHQ0|uniprotkb:Q7CH64	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:6pgl_yerpe(display_long)|uniprotkb:pgl(gene name)|psi-mi:pgl(display_short)|uniprotkb:YPO1149(locus name)|uniprotkb:y3033(locus name)|uniprotkb:YP_1011(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858760|imex:IM-13779-6347	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"refseq:YP_002346188.1|interpro:IPR022528|interpro:IPR019405|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0009051""(pentose-phosphate shunt, oxidative branch)|go:""GO:0017057""(6-phosphogluconolactonase activity)|refseq:WP_002210760.1|interpro:IPR050282|panther:PTHR30344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:noKVC/wB8Hf1xbPbMQHTszCjTss632	intact-crc:34EFB3A7E90873FE|rigid:5cQgWfEDNmi8JzxSYprs+qKAA38	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA77	intact:EBI-1033611	intact:EBI-2846955|uniprotkb:Q0WA77	-	psi-mi:glgc_yerpe(display_long)|uniprotkb:glgC(gene name)|psi-mi:glgC(display_short)|uniprotkb:ADP-glucose pyrophosphorylase(gene name synonym)|uniprotkb:ADP-glucose synthase(gene name synonym)|uniprotkb:YPO3940(locus name)|uniprotkb:y3888(locus name)|uniprotkb:YP_3302(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858732|imex:IM-13779-6343	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005836(ADP-glucose pyrophosphorylase, conserved site)|interpro:IPR011831(Glucose-1-phosphate adenylyltransferase)|interpro:IPR023049|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|go:""GO:0005524""(ATP binding)|go:""GO:0005978""(glycogen biosynthetic process)|go:""GO:0008878""(glucose-1-phosphate adenylyltransferase activity)|refseq:YP_002348811.1|panther:PTHR43523(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:B4k9ksS2wJK1E5De0OsPSPOXGQE632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:60BF95A7E9F93D66|rigid:QS+LMp1nPZW7FfhQegDHbCIEMOo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:Q8Z9U7	-	intact:EBI-2844315|uniprotkb:Q0W9T9	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:dnaa_yerpe(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:YPO4097(locus name)|uniprotkb:y4113(locus name)|uniprotkb:YP_4005(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858753|imex:IM-13779-6345	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR020591|interpro:IPR018312|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR024633|interpro:IPR027417|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002220732.1|interpro:IPR038454|refseq:YP_002348949.1|panther:PTHR30050(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:quI/wKd39km6/ursW/cA4L2/N8E632	intact-crc:2A7D4DA7E9EEAB51|rigid:+9KJ08R3dzcdJfGBrJ7YXgSi8lA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBY6	intact:EBI-1033611	intact:EBI-2855277|uniprotkb:Q0WC42	-	psi-mi:fade_yerpe(display_long)|uniprotkb:fadE(gene name)|psi-mi:fadE(display_short)|uniprotkb:YPO3244(locus name)|uniprotkb:y0946(locus name)|uniprotkb:YP_0688(locus name)	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858739|imex:IM-13779-6346	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050741|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR015396(Protein of unknown function DUF1974)|refseq:WP_002214691.1|interpro:IPR046373|go:""GO:0003995""(acyl-CoA dehydrogenase activity)|go:""GO:0004466""(long-chain fatty acyl-CoA dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0033539""(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070991""(medium-chain fatty acyl-CoA dehydrogenase activity)|interpro:IPR036250|interpro:IPR037069|interpro:IPR047634|refseq:YP_002348146.1|panther:PTHR48083(orthology-group)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1bMzTZsE58nKz8ZYNHjmsbYt9ZA632	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	intact-crc:F83606A7E9B1D0DC|rigid:dbnSaQeGaILD9uHTH4AA1TYsQ34	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75530	uniprotkb:A0A5P8YCV6	intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360.6|ensembl:ENSP00000500834.1	intact:EBI-2858767|uniprotkb:Q74QD8|uniprotkb:Q7CGW1|uniprotkb:A0A0H2W830|uniprotkb:Q0WII9	psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym)	psi-mi:a0a5p8ycv6_yerpe(display_long)|uniprotkb:YPO0848(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858771|imex:IM-13779-6350	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000074266.24(gene)|ensembl:ENST00000263360.11(transcript)|ensembl:ENST00000672825.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005829""(cytosol)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0021510""(spinal cord development)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0035098""(""ESC/E(Z) complex"")|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR051243|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6LO2|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|rcsb pdb:7MSB|rcsb pdb:7MSD|rcsb pdb:7P3C|rcsb pdb:7P3G|rcsb pdb:7P3J|rcsb pdb:7QJG|rcsb pdb:7QJU|rcsb pdb:7QK4|rcsb pdb:7SI4|rcsb pdb:7SI5|rcsb pdb:7TD5|rcsb pdb:8EQV|rcsb pdb:8FYH|rcsb pdb:8T9G|rcsb pdb:8TAS|rcsb pdb:8TB9|rcsb pdb:9C8U|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|refseq:NP_001294936.1|refseq:NP_003788.2|dip:DIP-36673N|efo:""Orphanet:659387""|efo:""Orphanet:659396""|panther:PTHR10253(orthology-group)"	"interpro:IPR033403|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR025887|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR048395|refseq:YP_002345899.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/17	rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606	rogid:T6J2RioWE2HPMThGMCH5c2P4t9c632	intact-crc:2DB1B70994D6AB17|rigid:5bSKo52mH5UU+4/+eVEgKHnv7ds	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q75MY8	uniprotkb:A0A5P8YI71	intact:EBI-2858803	intact:EBI-2858807|uniprotkb:A0A0H2W727|uniprotkb:Q74SE5|uniprotkb:Q7CJI3|uniprotkb:A0A384LGU2	psi-mi:q75my8_human(display_long)|uniprotkb:MX2(gene name)|psi-mi:MX2(display_short)	psi-mi:a0a5p8yi71_yerpe(display_long)|uniprotkb:YPO3044(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858811|imex:IM-13779-6348	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000375(Dynamin central region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)"	refseq:WP_002208540.1|refseq:YP_002347964.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zsU8K+EUeMVN0uAWQn/3EwhIsoE9606	rogid:4ZJ+Rfgc82ps/xlqGfQUPh7gxAE632	intact-crc:CD636A08B5C34AF4|rigid:2mqtM7mEHyjkw6ktIYBUVVgdE98	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75521	uniprotkb:A0A6B3UZY3	intact:EBI-2512024|ensembl:ENSP00000369461.3|uniprotkb:Q9NYH7|uniprotkb:Q9NQH1|uniprotkb:Q9H0T9|uniprotkb:Q5JYK7|uniprotkb:Q7L124|uniprotkb:Q9UN55|uniprotkb:Q9BUE9|uniprotkb:Q8N0X0|uniprotkb:Q5JYK5|intact:EBI-2802486	intact:EBI-2840340	"psi-mi:eci2_human(display_long)|uniprotkb:ECI2(gene name)|psi-mi:ECI2(display_short)|uniprotkb:DRS1(gene name synonym)|uniprotkb:HCA88(gene name synonym)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:""Delta(3),delta(2)-enoyl-CoA isomerase""(gene name synonym)|uniprotkb:Diazepam-binding inhibitor-related protein 1(gene name synonym)|uniprotkb:DRS-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 88(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-1(gene name synonym)|uniprotkb:PECI(gene name synonym)|uniprotkb:Peroxisomal 3,2-trans-enoyl-CoA isomerase(gene name synonym)"	psi-mi:a0a6b3uzy3_yerpe(display_long)|uniprotkb:barA(gene name)|psi-mi:barA(display_short)|uniprotkb:y0808(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858796|imex:IM-13779-6351	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000198721.13(gene)|ensembl:ENST00000380118.8(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0004165""(""delta(3)-delta(2)-enoyl-CoA isomerase activity"")|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0009062""(fatty acid catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR001753(Crotonase, core)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR022408|interpro:IPR029045|interpro:IPR035984|interpro:IPR051053|mint:O75521|rcsb pdb:2CQU|rcsb pdb:2F6Q|rcsb pdb:4U18|rcsb pdb:4U19|rcsb pdb:4U1A|reactome:R-HSA-390247|reactome:R-HSA-9033241|refseq:NP_001159482.1|refseq:NP_006108.2|refseq:NP_996667.2|panther:PTHR43684(orthology-group)"	"uniprotkb:Q8D1A1(uniprot-removed-ac)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008207(""Signal transduction histidine kinase, phosphotransfer (Hpt) region"")|interpro:IPR011006(CheY-like)|interpro:IPR019247|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|refseq:WP_002228321.1|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005886""(plasma membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AIR8lybsBusmVmjgsN0Hcl6p+3g9606	rogid:UceaICmR2UNiq3xdZ1868RlLXJ0632	intact-crc:457A519D4D970A4D|rigid:WDa1pmtQiMOnk122OBZDr42L1Ms	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6NXR2	uniprotkb:Q8D0C8	intact:EBI-2858778|uniprotkb:A8K0A1|uniprotkb:Q7Z5K6|uniprotkb:Q32NE4|uniprotkb:A6NMT8|uniprotkb:Q7L5M5	intact:EBI-2845934|uniprotkb:Q74UN2	psi-mi:stg31_human(display_long)|uniprotkb:STAG3L1(gene name)|psi-mi:STAG3L1(display_short)|uniprotkb:STAG3L2(gene name)|psi-mi:STAG3L2(display_short)|uniprotkb:STAG3L3(gene name)|psi-mi:STAG3L3(display_short)|uniprotkb:Stromal antigen 3-like(gene name synonym)	psi-mi:q8d0c8_yerpe(display_long)|uniprotkb:aRO81(gene name)|psi-mi:aRO81(display_short)|uniprotkb:YP_1678(locus name)|uniprotkb:y2375(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858789|imex:IM-13779-6349	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005488""(binding)|refseq:NP_001013761.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|ipi:IPI00556151|ipi:IPI00878533|ensembl:ENSG00000205583|ensembl:ENSG00000174353|ensembl:ENSG00000160828|refseq:NP_001020373.2|ipi:IPI00973263"	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR050859"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8HL4Dm/Gc+Qm6QXXEUQBCUrDdV49606	rogid:r71UI6xxi/cqjPI/E/qSei9l3XY632	intact-crc:DC36B21CDD6ADFE4|rigid:K9YlnUNkwzc5N//1Cg15HcuXDrA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q71V99	uniprotkb:A0A0H2W2X2	intact:EBI-2825563	intact:EBI-2858818|uniprotkb:Q0WDU3|uniprotkb:Q74VZ3|uniprotkb:Q7CJW2|uniprotkb:A0A3N4AZS0|uniprotkb:A0A384LI09	psi-mi:q71v99_human(display_long)	psi-mi:a0a0h2w2x2_yerpe(display_long)|uniprotkb:YPO2589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858822|imex:IM-13779-6352	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR024936|interpro:IPR029000|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006457""(protein folding)|go:""GO:0006915""(apoptotic process)|go:""GO:0016018""(cyclosporin A binding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)"	interpro:IPR007138(Antibiotic biosynthesis monooxygenase)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR050744|refseq:WP_002210309.1|refseq:YP_002347545.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VwIoW2yfdaAEwZj6MfekFYqkZjw9606	rogid:0kEdI4fSZxkyWdmdTWZNGfmW9lM632	intact-crc:54EDF8F3316DFBC7|rigid:rAdQSJhRCXAn8meZBH6s56hbzmM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B6K1	uniprotkb:P04440	intact:EBI-2841967|uniprotkb:Q7CHV2|uniprotkb:Q0WG31	intact:EBI-2802503|uniprotkb:Q9GIM2|uniprotkb:Q5EP47|uniprotkb:Q29682|uniprotkb:Q29879|uniprotkb:B8ZX68|uniprotkb:Q5EP52|uniprotkb:Q29698|uniprotkb:Q29827|uniprotkb:Q5EP46|uniprotkb:Q9XS11|uniprotkb:Q14279|uniprotkb:Q5YLA6|uniprotkb:O19700|uniprotkb:P01916|uniprotkb:B9W5S8|uniprotkb:O98219|uniprotkb:Q29778|uniprotkb:B9W6F9|uniprotkb:O19749|uniprotkb:Q30033|uniprotkb:Q5EP53|uniprotkb:Q9TQE2|uniprotkb:Q9GJ41|uniprotkb:Q29684|uniprotkb:O00259|uniprotkb:Q5I4H9|uniprotkb:A8YPB3|uniprotkb:P04232|uniprotkb:Q5ENE1|uniprotkb:C0MPP5|uniprotkb:Q30174|uniprotkb:Q29880|uniprotkb:Q8HWT5|uniprotkb:Q30052|uniprotkb:Q9TNT7|uniprotkb:Q5SQ73|uniprotkb:Q9BD13|uniprotkb:Q5EP51|uniprotkb:Q4JHD8|uniprotkb:Q860Z7|uniprotkb:Q5ENW3|uniprotkb:A0PFJ7|uniprotkb:Q6LBX3|uniprotkb:Q6LBX7|uniprotkb:B7VF87|uniprotkb:C0MPQ7|uniprotkb:Q30032|uniprotkb:Q9MY67|uniprotkb:Q5ISH4|uniprotkb:Q9XS12|uniprotkb:Q29977|uniprotkb:Q6PWX6|uniprotkb:Q30053|uniprotkb:Q0ZFN3|uniprotkb:Q5EP56|uniprotkb:Q27S71|uniprotkb:Q30050|uniprotkb:P79493|uniprotkb:P79608|uniprotkb:Q6LBX6|uniprotkb:Q0P0L4|uniprotkb:Q6IVX1|uniprotkb:Q30051|uniprotkb:O98216|uniprotkb:A5I886|uniprotkb:Q95IT7|uniprotkb:O98217|uniprotkb:Q29714|uniprotkb:O19698|uniprotkb:B5U8B4|uniprotkb:C5IZL1|uniprotkb:Q4GY31|uniprotkb:Q29775|uniprotkb:Q30054|uniprotkb:B7VF80|uniprotkb:O98215|uniprotkb:B8ZYT0|uniprotkb:Q30055|uniprotkb:Q29776|uniprotkb:C0MPQ5|uniprotkb:Q5STP2|uniprotkb:Q95IT8|uniprotkb:C0MPQ3|uniprotkb:Q6LBX2|uniprotkb:O98223|uniprotkb:C0MPQ6|uniprotkb:Q30034|uniprotkb:O46884|uniprotkb:Q29779|uniprotkb:Q6LBX4|uniprotkb:Q5ISH5|uniprotkb:C0MPQ2|uniprotkb:O19702|uniprotkb:Q8HWL7|uniprotkb:Q9GIX6|uniprotkb:Q29898|uniprotkb:Q2MGW3|uniprotkb:Q6TAS4|uniprotkb:O98218|uniprotkb:Q8SNC4|uniprotkb:Q29828|uniprotkb:Q9GIM4|uniprotkb:O77952|uniprotkb:Q7YQ10|uniprotkb:Q5EP49|uniprotkb:Q714U1|uniprotkb:Q6LBX5|uniprotkb:Q5I4H8|uniprotkb:B9W6F7|uniprotkb:Q95HC1|uniprotkb:P13763|uniprotkb:C4R9J5|uniprotkb:Q5ENE0|uniprotkb:Q30015|uniprotkb:Q30031|uniprotkb:Q29781|uniprotkb:O98222|uniprotkb:Q714U2|ensembl:ENSP00000382422.2|ensembl:ENSP00000389288.2|ensembl:ENSP00000396095.2|ensembl:ENSP00000407674.2|ensembl:ENSP00000408146.2|ensembl:ENSP00000414196.2	psi-mi:a0a3n4b6k1_yerpe(display_long)|uniprotkb:EIIAB-Man(gene name synonym)|uniprotkb:gptB(gene name)|psi-mi:gptB(display_short)|uniprotkb:EIII-Man(gene name synonym)|uniprotkb:manX(gene name synonym)|uniprotkb:ptsL(gene name synonym)|uniprotkb:YPO1758(locus name)	"psi-mi:dpb1_human(display_long)|uniprotkb:HLA-DP1B(gene name synonym)|uniprotkb:""HLA class II histocompatibility antigen, DP(W4) beta chain""(gene name synonym)|uniprotkb:MHC class II antigen DPB1(gene name synonym)|uniprotkb:HLA-DPB1(gene name)|psi-mi:HLA-DPB1(display_short)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858829|imex:IM-13779-6353	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004701(Phosphotransferase system, fructose subfamily IIA component)|interpro:IPR013789(Phosphotransferase system, fructose subfamily IIA component, subgroup)|interpro:IPR004720(Phosphotransferase system, sorbose subfamily IIB component)|interpro:IPR018455|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|interpro:IPR033887|interpro:IPR036662|interpro:IPR036667|refseq:WP_002211069.1|refseq:YP_002346757.1|interpro:IPR051471|panther:PTHR33799(orthology-group)"	"ensembl:ENSG00000215048.13(gene)|ensembl:ENSG00000223865.12(gene)|ensembl:ENSG00000226826.10(gene)|ensembl:ENSG00000230763.11(gene)|ensembl:ENSG00000236693.11(gene)|ensembl:ENSG00000237710.10(gene)|ensembl:ENST00000399500.6(transcript)|ensembl:ENST00000411749.6(transcript)|ensembl:ENST00000418931.7(transcript)|ensembl:ENST00000425130.6(transcript)|ensembl:ENST00000433800.6(transcript)|ensembl:ENST00000454006.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P04440|rcsb pdb:3LQZ|rcsb pdb:4P4K|rcsb pdb:4P4R|rcsb pdb:4P57|rcsb pdb:4P5K|rcsb pdb:4P5M|rcsb pdb:7T2A|rcsb pdb:7T2B|rcsb pdb:7T2C|rcsb pdb:7T2D|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_002112.3|efo:""Orphanet:133""|efo:""Orphanet:900""|panther:PTHR19944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6EMnus36OolbaozHpfdN+4jAtF0632	rogid:gy8rTenPR8u64fM9Kzl7ocoX3CM9606	intact-crc:5F9AE726DB77DD5B|rigid:7lhtrEZI3gpo1loZkuHO6IB2kX8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2858843	uniprotkb:Q8Z9R8	-	intact:EBI-2839934|uniprotkb:Q0W9Q7|intact:EBI-2857683|intact:EBI-2870000	psi-mi:q6zv67_human(display_short)|psi-mi:EBI-2858843(display_long)	psi-mi:mnmg_yerpe(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:YPO4130(locus name)|uniprotkb:y4144(locus name)|uniprotkb:YP_4037(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858845|imex:IM-13779-6356	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6ZV67(uniprot-removed-ac)	"interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|interpro:IPR044920|interpro:IPR026904|refseq:WP_002212259.1|interpro:IPR049312|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|interpro:IPR047001|refseq:YP_002348981.1|interpro:IPR040131|panther:PTHR11806(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:v90IkqKm+dlosxfAPKVYWCflBG4632	intact-crc:BBF34D72AB1A5DB5	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CWH0	uniprotkb:Q6ZV49	intact:EBI-2858855|uniprotkb:Q74S64	intact:EBI-2798219	psi-mi:q8cwh0_yerpe(display_long)|uniprotkb:dniR(gene name)|psi-mi:dniR(display_short)|uniprotkb:mltD(gene name synonym)|uniprotkb:YP_2771(locus name)|uniprotkb:y3098(locus name)	psi-mi:q6zv49_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858852|imex:IM-13779-6354	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023346|interpro:IPR008258(Lytic transglycosylase-like, catalytic)|interpro:IPR018392|interpro:IPR000189(Prokaryotic transglycosylase, active site)|go:""GO:0000270""(peptidoglycan metabolic process)|go:""GO:0008933""(peptidoglycan lytic transglycosylase activity)|go:""GO:0016020""(membrane)|go:""GO:0071555""(cell wall organization)|interpro:IPR036779"	interpro:IPR051860	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ea0Cr/VCEuVGJEDQP5qLl4XjFuY632	rogid:7usho4dmyTGVa3bYSx2PCfj6Nz49606	intact-crc:B47A2EB780F8CD11|rigid:kLLiv471m01nBzrHcSMT0FMk09A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04440	uniprotkb:Q8ZDX8	intact:EBI-2802503|uniprotkb:Q9GIM2|uniprotkb:Q5EP47|uniprotkb:Q29682|uniprotkb:Q29879|uniprotkb:B8ZX68|uniprotkb:Q5EP52|uniprotkb:Q29698|uniprotkb:Q29827|uniprotkb:Q5EP46|uniprotkb:Q9XS11|uniprotkb:Q14279|uniprotkb:Q5YLA6|uniprotkb:O19700|uniprotkb:P01916|uniprotkb:B9W5S8|uniprotkb:O98219|uniprotkb:Q29778|uniprotkb:B9W6F9|uniprotkb:O19749|uniprotkb:Q30033|uniprotkb:Q5EP53|uniprotkb:Q9TQE2|uniprotkb:Q9GJ41|uniprotkb:Q29684|uniprotkb:O00259|uniprotkb:Q5I4H9|uniprotkb:A8YPB3|uniprotkb:P04232|uniprotkb:Q5ENE1|uniprotkb:C0MPP5|uniprotkb:Q30174|uniprotkb:Q29880|uniprotkb:Q8HWT5|uniprotkb:Q30052|uniprotkb:Q9TNT7|uniprotkb:Q5SQ73|uniprotkb:Q9BD13|uniprotkb:Q5EP51|uniprotkb:Q4JHD8|uniprotkb:Q860Z7|uniprotkb:Q5ENW3|uniprotkb:A0PFJ7|uniprotkb:Q6LBX3|uniprotkb:Q6LBX7|uniprotkb:B7VF87|uniprotkb:C0MPQ7|uniprotkb:Q30032|uniprotkb:Q9MY67|uniprotkb:Q5ISH4|uniprotkb:Q9XS12|uniprotkb:Q29977|uniprotkb:Q6PWX6|uniprotkb:Q30053|uniprotkb:Q0ZFN3|uniprotkb:Q5EP56|uniprotkb:Q27S71|uniprotkb:Q30050|uniprotkb:P79493|uniprotkb:P79608|uniprotkb:Q6LBX6|uniprotkb:Q0P0L4|uniprotkb:Q6IVX1|uniprotkb:Q30051|uniprotkb:O98216|uniprotkb:A5I886|uniprotkb:Q95IT7|uniprotkb:O98217|uniprotkb:Q29714|uniprotkb:O19698|uniprotkb:B5U8B4|uniprotkb:C5IZL1|uniprotkb:Q4GY31|uniprotkb:Q29775|uniprotkb:Q30054|uniprotkb:B7VF80|uniprotkb:O98215|uniprotkb:B8ZYT0|uniprotkb:Q30055|uniprotkb:Q29776|uniprotkb:C0MPQ5|uniprotkb:Q5STP2|uniprotkb:Q95IT8|uniprotkb:C0MPQ3|uniprotkb:Q6LBX2|uniprotkb:O98223|uniprotkb:C0MPQ6|uniprotkb:Q30034|uniprotkb:O46884|uniprotkb:Q29779|uniprotkb:Q6LBX4|uniprotkb:Q5ISH5|uniprotkb:C0MPQ2|uniprotkb:O19702|uniprotkb:Q8HWL7|uniprotkb:Q9GIX6|uniprotkb:Q29898|uniprotkb:Q2MGW3|uniprotkb:Q6TAS4|uniprotkb:O98218|uniprotkb:Q8SNC4|uniprotkb:Q29828|uniprotkb:Q9GIM4|uniprotkb:O77952|uniprotkb:Q7YQ10|uniprotkb:Q5EP49|uniprotkb:Q714U1|uniprotkb:Q6LBX5|uniprotkb:Q5I4H8|uniprotkb:B9W6F7|uniprotkb:Q95HC1|uniprotkb:P13763|uniprotkb:C4R9J5|uniprotkb:Q5ENE0|uniprotkb:Q30015|uniprotkb:Q30031|uniprotkb:Q29781|uniprotkb:O98222|uniprotkb:Q714U2|ensembl:ENSP00000382422.2|ensembl:ENSP00000389288.2|ensembl:ENSP00000396095.2|ensembl:ENSP00000407674.2|ensembl:ENSP00000408146.2|ensembl:ENSP00000414196.2	intact:EBI-2846075|uniprotkb:Q0WEA5|uniprotkb:Q7CIU0|uniprotkb:Q74TF5	"psi-mi:dpb1_human(display_long)|uniprotkb:HLA-DP1B(gene name synonym)|uniprotkb:""HLA class II histocompatibility antigen, DP(W4) beta chain""(gene name synonym)|uniprotkb:MHC class II antigen DPB1(gene name synonym)|uniprotkb:HLA-DPB1(gene name)|psi-mi:HLA-DPB1(display_short)"	psi-mi:arna_yerpe(display_long)|uniprotkb:arnA(gene name)|psi-mi:arnA(display_short)|uniprotkb:YPO2420(locus name)|uniprotkb:y1919(locus name)|uniprotkb:YP_2207(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858836|imex:IM-13779-6355	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000215048.13(gene)|ensembl:ENSG00000223865.12(gene)|ensembl:ENSG00000226826.10(gene)|ensembl:ENSG00000230763.11(gene)|ensembl:ENSG00000236693.11(gene)|ensembl:ENSG00000237710.10(gene)|ensembl:ENST00000399500.6(transcript)|ensembl:ENST00000411749.6(transcript)|ensembl:ENST00000418931.7(transcript)|ensembl:ENST00000425130.6(transcript)|ensembl:ENST00000433800.6(transcript)|ensembl:ENST00000454006.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P04440|rcsb pdb:3LQZ|rcsb pdb:4P4K|rcsb pdb:4P4R|rcsb pdb:4P57|rcsb pdb:4P5K|rcsb pdb:4P5M|rcsb pdb:7T2A|rcsb pdb:7T2B|rcsb pdb:7T2C|rcsb pdb:7T2D|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_002112.3|efo:""Orphanet:133""|efo:""Orphanet:900""|panther:PTHR19944(orthology-group)"	"interpro:IPR021168|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|refseq:WP_002211823.1|go:""GO:0009103""(lipopolysaccharide biosynthetic process)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016831""(carboxy-lyase activity)|go:""GO:0046677""(response to antibiotic)|go:""GO:0099618""(UDP-glucuronate dehydrogenase activity)|go:""GO:0099619""(UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity)|interpro:IPR036291|interpro:IPR036477|refseq:YP_002347383.1|interpro:IPR050177|interpro:IPR045869|panther:PTHR43245(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gy8rTenPR8u64fM9Kzl7ocoX3CM9606	rogid:0CooVpb0kMelEinfekL5BXxuWUQ632	intact-crc:7A85FE384A8A5F66|rigid:DhSB+9nVJ4A7VykY+nsMz0EJ7Dc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZV49	uniprotkb:A0A5P8YCR4	intact:EBI-2798219	intact:EBI-2858882|uniprotkb:A0A0H2W7G3|uniprotkb:Q74QI8|uniprotkb:Q7CGQ9|uniprotkb:A0A384KMF4	psi-mi:q6zv49_human(display_long)	psi-mi:a0a5p8ycr4_yerpe(display_long)|uniprotkb:speC(gene name)|psi-mi:speC(display_short)|uniprotkb:YPO0960(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858887|imex:IM-13779-6358	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR051860	"interpro:IPR011006(CheY-like)|interpro:IPR005308(Orn/Lys/Arg decarboxylase, N-terminal)|interpro:IPR011193(Ornithine/lysine/arginine decarboxylase)|interpro:IPR000310(Orn/Lys/Arg decarboxylase, major region)|interpro:IPR008286(Orn/Lys/Arg decarboxylase, C-terminal)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR027464|interpro:IPR027568|refseq:WP_002210002.1|go:""GO:0004586""(ornithine decarboxylase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR036633|refseq:YP_002346006.1|panther:PTHR45229(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7usho4dmyTGVa3bYSx2PCfj6Nz49606	rogid:gaYKF9GoE6pCSNcI0eSktVOz620632	intact-crc:1E0D97621F942481|rigid:IH9bVvMD3Z8BPmPyYPN6ZThIGWM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZV49	uniprotkb:A0A2S9PBJ0	intact:EBI-2798219	intact:EBI-2858904|uniprotkb:Q74RX0|uniprotkb:A0A380PM03|uniprotkb:Q7CGC5|uniprotkb:A0A0H2W7X2	psi-mi:q6zv49_human(display_long)	psi-mi:a0a2s9pbj0_yerpe(display_long)|uniprotkb:yqjA(gene name)|psi-mi:yqjA(display_short)|uniprotkb:YPO0574(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858901|imex:IM-13779-6361	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR051860	"interpro:IPR032816|interpro:IPR032818|refseq:WP_002210414.1|go:""GO:0005886""(plasma membrane)|refseq:YP_002345646.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7usho4dmyTGVa3bYSx2PCfj6Nz49606	rogid:w4DTBfb0g5Hhs/5EQ9Uu0bDlxeI632	intact-crc:6E3C9B8389A78A72|rigid:2Ecm4vtLhOPAppDIGJO8Tbe5kV0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKV8	uniprotkb:Q6ZV49	intact:EBI-2843133	intact:EBI-2798219	psi-mi:q8ckv8_yerpe(display_long)|uniprotkb:y2773(locus name)	psi-mi:q6zv49_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858864|imex:IM-13779-6357	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	interpro:IPR051860	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CvpkOm4oTIkR/qXV0+wE+2oZeTk632	rogid:7usho4dmyTGVa3bYSx2PCfj6Nz49606	intact-crc:978D72B78219D28E|rigid:e0QxRh5f2kvt6nXJZr5WJHpEq9k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W2Z9	uniprotkb:Q6ZV49	intact:EBI-2858874|uniprotkb:Q74XH6|uniprotkb:A0A5P8YBN3|uniprotkb:Q7CKQ6|uniprotkb:Q0WK16	intact:EBI-2798219	psi-mi:a0a0h2w2z9_yerpe(display_long)|uniprotkb:YPO0290(locus name)	psi-mi:q6zv49_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858871|imex:IM-13779-6360	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR011215(Uncharacterised conserved protein UCP020979)|interpro:IPR028157|refseq:WP_002209070.1|interpro:IPR048336|refseq:YP_002345372.1	interpro:IPR051860	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tkiAUX1x4Qx0pUonilOsHwLapVo632	rogid:7usho4dmyTGVa3bYSx2PCfj6Nz49606	intact-crc:35CF8CEB8C8E309E|rigid:xNpKhGpYkUEepyrvr+H2PiQDKQk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZV49	uniprotkb:Q7CGI0	intact:EBI-2798219	intact:EBI-2840021|uniprotkb:Q74RN4	psi-mi:q6zv49_human(display_long)	psi-mi:ftsp_yerpe(display_long)|uniprotkb:ftsP(gene name)|psi-mi:ftsP(display_short)|uniprotkb:YPO0673(locus name)|uniprotkb:YP_2989(locus name)|uniprotkb:y3504(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858894|imex:IM-13779-6359	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR051860	"refseq:YP_002345741.1|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR008972(Cupredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR026589|refseq:WP_002212176.1|go:""GO:0005507""(copper ion binding)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|interpro:IPR045087|panther:PTHR11709(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7usho4dmyTGVa3bYSx2PCfj6Nz49606	rogid:JQTwQ8R/Yza07pQepCvAhD8UkWA632	intact-crc:664C8A4E5FF89421|rigid:UIDo6Cy9NaNs5zJ3UWevDYLj8oQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHH3	uniprotkb:Q6ZV49	intact:EBI-2857394|uniprotkb:Q0WIB9	intact:EBI-2798219	psi-mi:pgk_yerpe(display_long)|uniprotkb:pgk(gene name)|psi-mi:pgk(display_short)|uniprotkb:YPO0921(locus name)|uniprotkb:y3308(locus name)|uniprotkb:YP_3519(locus name)	psi-mi:q6zv49_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858913|imex:IM-13779-6366	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|refseq:WP_002209963.1|go:""GO:0004618""(phosphoglycerate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0043531""(ADP binding)|interpro:IPR036043|refseq:YP_002345969.1|panther:PTHR11406(orthology-group)"	interpro:IPR051860	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NB2BLC2gD2al0+rea01wVtP5/iU632	rogid:7usho4dmyTGVa3bYSx2PCfj6Nz49606	intact-crc:A90F005E801DCA23|rigid:Um1DNgUBnUo+C3Ggn3CK3q9jSJI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D045	intact:EBI-2858927	intact:EBI-2843214|uniprotkb:Q74VS8	-	psi-mi:q8d045_yerpe(display_long)|uniprotkb:y2788(locus name)	psi-mi:q6zum1_human(display_short)|psi-mi:EBI-2858927(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858929|imex:IM-13779-6365	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR041080|interpro:IPR003776(YcaO-like)	uniprotkb:Q6ZUM1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eDZjumGXqh186vyaDbx1D0kzPg8632	-	intact-crc:07164F190A0311C4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKV8	intact:EBI-2858927	intact:EBI-2843133	-	psi-mi:q8ckv8_yerpe(display_long)|uniprotkb:y2773(locus name)	psi-mi:q6zum1_human(display_short)|psi-mi:EBI-2858927(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858936|imex:IM-13779-6363	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	uniprotkb:Q6ZUM1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CvpkOm4oTIkR/qXV0+wE+2oZeTk632	-	intact-crc:A781164E09DC7E40	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H144	intact:EBI-2858927	intact:EBI-2841538|uniprotkb:O68732|uniprotkb:Q74YQ2|uniprotkb:A0A0H2VZE7|uniprotkb:Q7ARF6|uniprotkb:A0A384L8C6|uniprotkb:A0A1U8QFZ7	-	psi-mi:a0a2u2h144_yerpe(display_long)|uniprotkb:YPMT1.15c(locus name)	psi-mi:q6zum1_human(display_short)|psi-mi:EBI-2858927(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858943|imex:IM-13779-6364	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395351.1|refseq:YP_093892.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|refseq:WP_002211779.1|interpro:IPR024411"	uniprotkb:Q6ZUM1(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xq2Ec6P3nSErFowcd9WtA5SDDC0632	-	intact-crc:6F17B51B1935A7F3	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZV49	uniprotkb:Q8ZGY5	intact:EBI-2798219	intact:EBI-2841765|uniprotkb:Q0WHR3	psi-mi:q6zv49_human(display_long)	psi-mi:gpma_yerpe(display_long)|uniprotkb:gpmA(gene name)|psi-mi:gpmA(display_short)|uniprotkb:YPO1133(locus name)|uniprotkb:y3048(locus name)|uniprotkb:YP_1025(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858920|imex:IM-13779-6362	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR051860	"interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR029033|interpro:IPR013078(Phosphoglycerate mutase)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0046538""(obsolete 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity)|refseq:YP_002346175.1|refseq:WP_002210746.1|panther:PTHR11931(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7usho4dmyTGVa3bYSx2PCfj6Nz49606	rogid:w14CAyFDgSjT7kqFQjVHzHi0wRc632	intact-crc:1197DF5E81D2594D|rigid:yUuZNA07i16Fq7swsTat2KNOn0s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2815295	uniprotkb:A0A0H2W225	-	intact:EBI-2844774	psi-mi:q6zv49_human(display_short)|psi-mi:EBI-2815295(display_long)	psi-mi:a0a0h2w225_yerpe(display_long)|uniprotkb:sbcC2(gene name)|psi-mi:sbcC2(display_short)|uniprotkb:sbcC(gene name synonym)|uniprotkb:YP_0725(locus name)|uniprotkb:y0976(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858960|imex:IM-13779-6369	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6ZTC2(uniprot-removed-ac)	"interpro:IPR027417|interpro:IPR038729|uniprotkb:A0A6B3T1W4(uniprot-removed-ac)|go:""GO:0004527""(exonuclease activity)|go:""GO:0006302""(double-strand break repair)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002223265.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:kLIIS2zCAycudIvZsl7pSdsTqz0632	intact-crc:2333C376A16CF0BA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZTQ9	uniprotkb:P68587	intact:EBI-2858950	intact:EBI-2844901|uniprotkb:P40295	psi-mi:q6ztq9_human(display_long)	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858953|imex:IM-13779-6367	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y6Nye2HrDrwx/nRdgPLaimTHKVs9606	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	intact-crc:3F4E8CBA58DF564F|rigid:7C1zU1UqOD7UiEJlliJhwi0hfuo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2815295	uniprotkb:A0A5P8YCV0	-	intact:EBI-2847775|uniprotkb:Q74Q84|uniprotkb:Q0WIC7|uniprotkb:Q7CGS8|uniprotkb:A0A384L1X8	psi-mi:q6zv49_human(display_short)|psi-mi:EBI-2815295(display_long)	psi-mi:a0a5p8ycv0_yerpe(display_long)|uniprotkb:YPO0913(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858967|imex:IM-13779-6370	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6ZTC2(uniprot-removed-ac)	"interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|refseq:WP_002209955.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009396""(folic acid-containing compound biosynthetic process)|go:""GO:0030272""(5-formyltetrahydrofolate cyclo-ligase activity)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|interpro:IPR024185|interpro:IPR037171|refseq:YP_002345961.1|panther:PTHR23407(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:10+1hunnZ1E8GkdgkFMuY64dDRY632	intact-crc:FF96187F5E6203AC	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2858978	uniprotkb:A0A2U2GUZ8	-	intact:EBI-2858974|uniprotkb:Q74PU1|uniprotkb:A0A380PJ37|uniprotkb:Q0WJS3|uniprotkb:Q7CG32|uniprotkb:A0A384L519	psi-mi:q6ztb6_human(display_short)|psi-mi:EBI-2858978(display_long)	psi-mi:a0a2u2guz8_yerpe(display_long)|uniprotkb:YPO0388(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858980|imex:IM-13779-6368	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6ZTB6(uniprot-removed-ac)	interpro:IPR019292|refseq:WP_002209167.1|refseq:YP_002345465.1	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:KAzzgB6fVtKcGVFVzqcVYB96Yyk632	intact-crc:91562929E878E012	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2845675	uniprotkb:P74989	-	intact:EBI-2844339|uniprotkb:Q7CI67|uniprotkb:Q74UL3|uniprotkb:A0A384KQE5|uniprotkb:A0A1U8QXW3|uniprotkb:A0A380PD48	psi-mi:q6zsk6_human(display_short)|psi-mi:EBI-2845675(display_long)	psi-mi:p74989_yerpe(display_long)|uniprotkb:hmsS(gene name)|psi-mi:hmsS(display_short)|uniprotkb:YPO1954(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859014|imex:IM-13779-6373	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6ZSK6(uniprot-removed-ac)	"interpro:IPR023829|go:""GO:0016020""(membrane)|go:""GO:0043709""(cell adhesion involved in single-species biofilm formation)|refseq:WP_002212041.1|refseq:YP_002346943.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:6hXM7XL95ZWCW9EgS2OwTXd5FkQ632	intact-crc:9D30F1F364F7AD29	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P69961	intact:EBI-2858990	intact:EBI-2847280|uniprotkb:Q663H6|uniprotkb:Q00931	-	psi-mi:lcrs_yerpe(display_long)|uniprotkb:lcrS(gene name)|psi-mi:lcrS(display_short)|uniprotkb:YPCD1.63(locus name)|uniprotkb:y5015(locus name)|uniprotkb:y0018(locus name)|uniprotkb:YP_pCD20(locus name)	psi-mi:q6zt02_human(display_short)|psi-mi:EBI-2858990(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858996|imex:IM-13779-6374	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002514(Transposase IS3/IS911)|refseq:NP_395197.1|refseq:NP_857719.1|refseq:NP_857914.1|interpro:IPR009057(Homeodomain-like)|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|interpro:IPR052546|panther:PTHR33609(orthology-group)"	uniprotkb:Q6ZT02(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qN+XjQYD6AUbLCv9ZgB3dougULw632	-	intact-crc:D5EA837B65048A8A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2858990	uniprotkb:P58644	-	intact:EBI-2847265|uniprotkb:Q0WET9	psi-mi:q6zt02_human(display_short)|psi-mi:EBI-2858990(display_long)	psi-mi:pyrf_yerpe(display_long)|uniprotkb:pyrF(gene name)|psi-mi:pyrF(display_short)|uniprotkb:OMP decarboxylase(gene name synonym)|uniprotkb:YPO2227(locus name)|uniprotkb:y2069(locus name)|uniprotkb:YP_2026(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2858987|imex:IM-13779-6371	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6ZT02(uniprot-removed-ac)	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR014732(Orotidine 5'-phosphate decarboxylase, subfamily 1, core)|interpro:IPR018089|interpro:IPR001754(Orotidine 5'-phosphate decarboxylase, core)|interpro:IPR011060(Ribulose-phosphate binding barrel)|refseq:WP_002210613.1|go:""GO:0004590""(orotidine-5'-phosphate decarboxylase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|interpro:IPR047596|refseq:YP_002347199.1|panther:PTHR32119(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:dtw0gJaLqe7+VDQVDgj+DE1VQvg632	intact-crc:CFD5A4F5DC7679CC	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZSC8	uniprotkb:A0A0H2W3B5	intact:EBI-2815312	intact:EBI-2859024|uniprotkb:Q74X49|uniprotkb:A0A380PIS3|uniprotkb:Q7CKH5|uniprotkb:Q0WBH7	psi-mi:q6zsc8_human(display_long)	psi-mi:a0a0h2w3b5_yerpe(display_long)|uniprotkb:YPO3472(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859021|imex:IM-13779-6375	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031152|go:""GO:0016020""(membrane)"	"interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|refseq:WP_002209277.1|go:""GO:0030313""(cell envelope)|interpro:IPR050490|refseq:YP_002348361.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NC2eSxR2c8bo5BscH7HDLDlHfcM9606	rogid:XnetQP8uHUepV3OgVBaaloDQvS8632	intact-crc:2858FDBDB7AFDA82|rigid:mKgRvC40tawl2uvgVmEiDsehY3I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2845675	uniprotkb:A0A6M0NJJ8	-	intact:EBI-2859006	psi-mi:q6zsk6_human(display_short)|psi-mi:EBI-2845675(display_long)	psi-mi:a0a6m0njj8_yerpe(display_long)|uniprotkb:zntA(gene name)|psi-mi:zntA(display_short)|uniprotkb:y0410(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859003|imex:IM-13779-6372	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6ZSK6(uniprot-removed-ac)	"uniprotkb:A0A6B3T3U5(uniprot-removed-ac)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR017969|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR027256|interpro:IPR036163|interpro:IPR036412|interpro:IPR044492|interpro:IPR051014|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015662""(P-type ion transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019829""(ATPase-coupled monoatomic cation transmembrane transporter activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002231925.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:+CzYQMblOQc5YaMubF8rba/RSxo632	intact-crc:1A36B1F006EC2A0E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZRX4	uniprotkb:P69974	intact:EBI-2859042	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	psi-mi:q6zrx4_human(display_long)	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859045|imex:IM-13779-6376	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dzXsZytBmUz7H5+9UmC+Cv5mwgU9606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:3CD001D5EEE0BB02|rigid:gLowtCe2+N6CTanNhXhPqf6lGsI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2825685	uniprotkb:Q8CKI8	-	intact:EBI-2855532	psi-mi:q6zrz6_human(display_short)|psi-mi:EBI-2825685(display_long)	psi-mi:q8cki8_yerpe(display_long)|uniprotkb:NCTC5923_02392(orf name)|uniprotkb:y3427(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859052|imex:IM-13779-6377	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6ZRJ3(uniprot-removed-ac)	refseq:WP_002213742.1	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:kFpagl9Qd6b6ImFRX9++a7dnIjA632	intact-crc:5EFFB13E2F5156B4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2859036	uniprotkb:A0A2U2GXH7	-	intact:EBI-2848470|uniprotkb:Q74WH6|uniprotkb:Q0WHG3|uniprotkb:A0A0H2W2J4|uniprotkb:Q7CHB5|uniprotkb:A0A384K9G2	psi-mi:q6zrx5_human(display_short)|psi-mi:EBI-2859036(display_long)	psi-mi:a0a2u2gxh7_yerpe(display_long)|uniprotkb:YPO1246(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859033|imex:IM-13779-6378	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6ZRX5(uniprot-removed-ac)	interpro:IPR009826(DNA circulation, N-terminal)|refseq:WP_002208852.1|refseq:YP_002346275.1|interpro:IPR052399	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:Qbi9eC3jfsnnPhDaTUvn+57rY7s632	intact-crc:DECADBDAA47C16D6	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H2W8	intact:EBI-2845685	intact:EBI-2859062|uniprotkb:Q74R22|uniprotkb:A0A5P8YCG3|uniprotkb:A0A0H2W7C6|uniprotkb:Q7CKV2|uniprotkb:A0A384L4Z3	-	psi-mi:a0a2u2h2w8_yerpe(display_long)|uniprotkb:YPO3785(locus name)	psi-mi:q6zrb0_human(display_short)|psi-mi:EBI-2845685(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859059|imex:IM-13779-6379	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026893|interpro:IPR029021|refseq:WP_002228183.1|go:""GO:0004721""(phosphoprotein phosphatase activity)|refseq:YP_002348662.1"	uniprotkb:Q6ZRB0(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/6YZnelr1WaabkYNEObn+bBuB6E632	-	intact-crc:AB5502A8F891C755	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B9Y1	uniprotkb:Q6ZN12	intact:EBI-2846283|uniprotkb:Q74XU0|uniprotkb:Q0WBQ4|uniprotkb:Q7CKD5|uniprotkb:A0A384LCY5	intact:EBI-2859087	psi-mi:a0a3n4b9y1_yerpe(display_long)|uniprotkb:fhuC(gene name)|psi-mi:fhuC(display_short)|uniprotkb:YPO3392(locus name)	psi-mi:q6zn12_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859090|imex:IM-13779-6383	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR027417|refseq:WP_002209359.1|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006826""(iron ion transport)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_002348284.1|interpro:IPR051535|panther:PTHR42771(orthology-group)"	"interpro:IPR054361|interpro:IPR000571(Zinc finger, CCCH-type)|refseq:NP_940983.2|go:""GO:0003723""(RNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR036855|interpro:IPR045124"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:G0PFXVTTvSHCqaLV10fe+uJnEh8632	rogid:vE5dGeLHs3uZhugyzjNq5Fk19H89606	intact-crc:3AB8B606AFEB3274|rigid:XuEtWLvuPMHRkP0f7JhrFdUD3iM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5L7Y0	uniprotkb:Q7Z2F6	intact:EBI-2853824	intact:EBI-2796279|ensembl:ENSP00000319222.9|uniprotkb:Q6ZQX1	psi-mi:a0a3g5l7y0_yerpe(display_long)|uniprotkb:sfcA2(gene name)|psi-mi:sfcA2(display_short)|uniprotkb:YP_2657(locus name)|uniprotkb:y1449(locus name)	psi-mi:krbx5_human(display_long)|uniprotkb:KRBOX5(gene name)|psi-mi:KRBOX5(display_short)|uniprotkb:ZNF720(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859070|imex:IM-13779-6384	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051674|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|interpro:IPR012188(Malic enzyme, phosphate acetyl/butaryl transferase)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR036291|interpro:IPR037062|interpro:IPR042112|interpro:IPR042113|uniprotkb:A0A6B3T265(uniprot-removed-ac)|go:""GO:0004470""(malic enzyme activity)|go:""GO:0006108""(malate metabolic process)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051287""(NAD binding)|interpro:IPR045213|refseq:WP_002224829.1|interpro:IPR046346"	"ensembl:ENSG00000197302.11(gene)|ensembl:ENST00000316491.14(transcript)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR036051|interpro:IPR050169|reactome:R-HSA-212436|refseq:NP_001124385.1|panther:PTHR23232(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:stWUfKx3Suo1T8GcyMQBEsNHMII632	rogid:43PvXdswJf+g/kFex3W+v9jjv4Q9606	intact-crc:B47F24C022842908|rigid:idJdEsboEnNZtErGC4eIwoT9czY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2859077	uniprotkb:A0A0H2W7E2	-	intact:EBI-2848155|uniprotkb:A0A2U2H0T1|uniprotkb:Q74QL8|uniprotkb:Q0WI49|uniprotkb:Q7CGN6|uniprotkb:A0A384KKB9	psi-mi:yv021_human(display_short)|psi-mi:EBI-2859077(display_long)	psi-mi:a0a0h2w7e2_yerpe(display_long)|uniprotkb:iutA(gene name)|psi-mi:iutA(display_short)|uniprotkb:YPO0994(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859080|imex:IM-13779-6380	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6ZQP7(uniprot-removed-ac)	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|refseq:WP_002211646.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002346039.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kdsXhzGEaMSzcjhDcs2UqcTBrHo9606	rogid:h+zziPxtFmhqRng+3zCsRqmsI/M632	intact-crc:11D64D646B88A486|rigid:BFqtLa+IwjoxyIzjvWsGENPaK2s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15149	uniprotkb:P58543	intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763|ensembl:ENSP00000323856.4	intact:EBI-2847390|uniprotkb:Q0WER7	psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:arab_yerpe(display_long)|uniprotkb:araB(gene name)|psi-mi:araB(display_short)|uniprotkb:YPO2254(locus name)|uniprotkb:y2095(locus name)|uniprotkb:YP_2050(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859097|imex:IM-13779-6381	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1114""|efo:""Orphanet:158684""|efo:""Orphanet:254361""|efo:""Orphanet:257""|efo:""Orphanet:79401""|ensembl:ENSG00000178209.17(gene)|ensembl:ENST00000322810.8(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0002102""(podosome)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0002522""(leukocyte migration involved in immune response)|go:""GO:0003334""(keratinocyte development)|go:""GO:0003723""(RNA binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005925""(focal adhesion)|go:""GO:0006997""(nucleus organization)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008104""(protein localization)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0010467""(gene expression)|go:""GO:0010761""(fibroblast migration)|go:""GO:0010818""(T cell chemotaxis)|go:""GO:0014866""(skeletal myofibril assembly)|go:""GO:0016528""(sarcoplasm)|go:""GO:0019226""(transmission of nerve impulse)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0030018""(Z disc)|go:""GO:0030056""(hemidesmosome)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030506""(ankyrin binding)|go:""GO:0031581""(hemidesmosome assembly)|go:""GO:0032094""(response to food)|interpro:IPR035915|go:""GO:0032287""(peripheral nervous system myelin maintenance)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0042060""(wound healing)|go:""GO:0042383""(sarcolemma)|go:""GO:0042802""(identical protein binding)|go:""GO:0043034""(costamere)|go:""GO:0043114""(regulation of vascular permeability)|go:""GO:0043209""(myelin sheath)|go:""GO:0043933""(protein-containing complex organization)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0045109""(intermediate filament organization)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048741""(skeletal muscle fiber development)|go:""GO:0051015""(actin filament binding)|go:""GO:0055013""(cardiac muscle cell development)|go:""GO:0061436""(establishment of skin barrier)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071464""(cellular response to hydrostatic pressure)|go:""GO:0071498""(cellular response to fluid shear stress)|go:""GO:0120193""(tight junction organization)|go:""GO:2000689""(actomyosin contractile ring assembly actin filament organization)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|interpro:IPR049538|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1|panther:PTHR23169(orthology-group)"	"interpro:IPR018485|interpro:IPR005929(L-ribulokinase)|interpro:IPR043129|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008741""(ribulokinase activity)|go:""GO:0019150""(D-ribulokinase activity)|go:""GO:0019321""(pentose metabolic process)|go:""GO:0019569""(L-arabinose catabolic process to xylulose 5-phosphate)|refseq:YP_002347221.1|panther:PTHR43435(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606	rogid:hejpPk7Q+tUU+cmG5v4jTehB47I632	intact-crc:A8479FBBEE766B26|rigid:8BDftUeg3qmhOBuLBwF9kJs2UEI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2802728	uniprotkb:Q8CLU1	-	intact:EBI-2858457|uniprotkb:Q74PI9	psi-mi:q6pj02_human(display_short)|psi-mi:EBI-2802728(display_long)	psi-mi:q8clu1_yerpe(display_long)|uniprotkb:YP_3916(locus name)|uniprotkb:y0237(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859104|imex:IM-13779-6382	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6PJ02(uniprot-removed-ac)	-	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:0uc/wKxOf6SolN7v6B1IoBBJqMM632	intact-crc:6CCBBDEFD356EDCB	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YHJ0	intact:EBI-2802728	intact:EBI-2840822|uniprotkb:A0A384KBR7|uniprotkb:Q0WCM8|uniprotkb:Q7CJI0	-	psi-mi:a0a5p8yhj0_yerpe(display_long)|uniprotkb:napF(gene name)|psi-mi:napF(display_short)|uniprotkb:YPO3040(locus name)	psi-mi:q6pj02_human(display_short)|psi-mi:EBI-2802728(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859118|imex:IM-13779-6387	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR004496(Ferredoxin-type protein NapF)|refseq:YP_002347960.1|interpro:IPR017900|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002208536.1|interpro:IPR050572|panther:PTHR24960(orthology-group)"	uniprotkb:Q6PJ02(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eff9jqgNqHt/SEUvObWFEj5j/tU632	-	intact-crc:011FB27CF4708609	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W0Z5	intact:EBI-2859135	intact:EBI-2844986|uniprotkb:Q74Y40|uniprotkb:Q0WKG8|uniprotkb:Q7CFX1|uniprotkb:A0A380PIN3|uniprotkb:A0A384LBS1	-	psi-mi:a0a0h2w0z5_yerpe(display_long)|uniprotkb:YPO0134(locus name)	psi-mi:q6p6a7_human(display_short)|psi-mi:EBI-2859135(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859132|imex:IM-13779-6386	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR023323|interpro:IPR023319|interpro:IPR018974|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR044146|refseq:WP_002208916.1|go:""GO:0003676""(nucleic acid binding)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|interpro:IPR055179|interpro:IPR032639|interpro:IPR037027|interpro:IPR041692|refseq:YP_002345220.1|interpro:IPR050437"	uniprotkb:Q6P6A7(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ttlZGvCMP/bbGv1PpYdheTErKIk632	-	intact-crc:A80B9CFF6EC2D179	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2802728	uniprotkb:Q8CKW7	-	intact:EBI-2845318	psi-mi:q6pj02_human(display_short)|psi-mi:EBI-2802728(display_long)	psi-mi:q8ckw7_yerpe(display_long)|uniprotkb:y2698(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859111|imex:IM-13779-6385	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6PJ02(uniprot-removed-ac)	refseq:WP_002231240.1|interpro:IPR028244|interpro:IPR018769|interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:Nrvz9YxMF2TgzN5e3ZNazVacK34632	intact-crc:523BEAEFD29C56B4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8Z9S7	intact:EBI-2802728	intact:EBI-2843785|uniprotkb:Q74PA2|uniprotkb:Q0W9R8|uniprotkb:Q8CZF5	-	psi-mi:glmu_yerpe(display_long)|uniprotkb:glmU(gene name)|psi-mi:glmU(display_short)|uniprotkb:YPO4119(locus name)|uniprotkb:y4133(locus name)|uniprotkb:YP_4026(locus name)	psi-mi:q6pj02_human(display_short)|psi-mi:EBI-2802728(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859125|imex:IM-13779-6388	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:4FCE|interpro:IPR029044|interpro:IPR005882(UDP-N-acetylglucosamine pyrophosphorylase)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR018357|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR025877|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003977""(UDP-N-acetylglucosamine diphosphorylase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019134""(glucosamine-1-phosphate N-acetyltransferase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR038009|refseq:WP_002215550.1|refseq:YP_002348970.1|interpro:IPR050065|panther:PTHR43584(orthology-group)"	uniprotkb:Q6PJ02(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9qnSgGL+fCmXV2kMl5dYnODFWqw632	-	intact-crc:3B95B906D29D3707	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IZD2	uniprotkb:A0A2U2GXH4	intact:EBI-2689959|uniprotkb:Q86TI3|uniprotkb:B6ZDM3|uniprotkb:Q8IWR5|uniprotkb:B6ZDE4|uniprotkb:Q6P5Y2|uniprotkb:Q86WG0|uniprotkb:Q86W12|uniprotkb:Q8NFF8|uniprotkb:Q8IV78|uniprotkb:Q86WL2|uniprotkb:Q6T316|uniprotkb:Q9NWE7|uniprotkb:Q6PKG4|intact:EBI-2815322|uniprotkb:M4K8J3|intact:EBI-28975207|ensembl:ENSP00000312379.3	intact:EBI-2855070|uniprotkb:Q0WHE9|uniprotkb:A0A380PMU6|uniprotkb:Q7CHC4|uniprotkb:A0A384KKM6	psi-mi:kmt2e_human(display_long)|uniprotkb:KMT2E(gene name)|psi-mi:KMT2E(display_short)|uniprotkb:MLL5(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 5(gene name synonym)	psi-mi:a0a2u2gxh4_yerpe(display_long)|uniprotkb:YPO1260(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859141|imex:IM-13779-6389	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000005483.23(gene)|ensembl:ENST00000311117.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0002446""(neutrophil mediated immunity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016604""(nuclear body)|go:""GO:0016607""(nuclear speck)|go:""GO:0019899""(enzyme binding)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034967""(Set3 complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0042119""(neutrophil activation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0070210""(Rpd3L-Expanded complex)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR044434|interpro:IPR046341|rcsb pdb:2LV9|rcsb pdb:4L58|rcsb pdb:5HT6|refseq:NP_061152.3|refseq:NP_891847.1|refseq:XP_005250550.1|refseq:XP_011514702.1|panther:PTHR46462(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR012159(Membrane sulphatase, HI0842-related)|interpro:IPR024588|interpro:IPR000917(Sulphatase)|interpro:IPR047997|refseq:WP_002208837.1|go:""GO:0005886""(plasma membrane)|interpro:IPR052701|refseq:YP_002346289.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:R88sB8694YH12wYZLv4PLcpqegU9606	rogid:nMNkk/9JyQnEZEr48ZNjLZzy2Dc632	intact-crc:E2CC12CE502590CA|rigid:hHEi95aV3GqRhAZu/G1EAChGVus	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P68587	intact:EBI-2796107	intact:EBI-2844901|uniprotkb:P40295	-	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	psi-mi:q6p491_human(display_short)|psi-mi:EBI-2796107(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859160|imex:IM-13779-6390	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	uniprotkb:Q6P491(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	-	intact-crc:4805FE7206B6A5FF	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2796107	uniprotkb:Q8CZW4	-	intact:EBI-2851384|uniprotkb:Q74QA0	psi-mi:q6p491_human(display_short)|psi-mi:EBI-2796107(display_long)	psi-mi:q8czw4_yerpe(display_long)|uniprotkb:y3277(locus name)|uniprotkb:fldB(gene name)|psi-mi:fldB(display_short)|uniprotkb:YP_3589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859167|imex:IM-13779-6391	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6P491(uniprot-removed-ac)	"interpro:IPR029039|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001226(Flavodoxin, conserved site)|interpro:IPR010086(Flavodoxin, long chain)|go:""GO:0009055""(electron transfer activity)|go:""GO:0010181""(FMN binding)|interpro:IPR050619"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:FZlCLDczSf2Gjm4UsIPSSoGJH6E632	intact-crc:2BB95436CC908DD6	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IZD2	uniprotkb:Q7CHM0	intact:EBI-2689959|uniprotkb:Q86TI3|uniprotkb:B6ZDM3|uniprotkb:Q8IWR5|uniprotkb:B6ZDE4|uniprotkb:Q6P5Y2|uniprotkb:Q86WG0|uniprotkb:Q86W12|uniprotkb:Q8NFF8|uniprotkb:Q8IV78|uniprotkb:Q86WL2|uniprotkb:Q6T316|uniprotkb:Q9NWE7|uniprotkb:Q6PKG4|intact:EBI-2815322|uniprotkb:M4K8J3|intact:EBI-28975207|ensembl:ENSP00000312379.3	intact:EBI-2859148|uniprotkb:Q74VH4	psi-mi:kmt2e_human(display_long)|uniprotkb:KMT2E(gene name)|psi-mi:KMT2E(display_short)|uniprotkb:MLL5(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 5(gene name synonym)	psi-mi:hspq_yerpe(display_long)|uniprotkb:hspQ(gene name)|psi-mi:hspQ(display_short)|uniprotkb:YPO1444(locus name)|uniprotkb:y2726(locus name)|uniprotkb:YP_1335(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859153|imex:IM-13779-6392	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000005483.23(gene)|ensembl:ENST00000311117.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0002446""(neutrophil mediated immunity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016604""(nuclear body)|go:""GO:0016607""(nuclear speck)|go:""GO:0019899""(enzyme binding)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034967""(Set3 complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0042119""(neutrophil activation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0070210""(Rpd3L-Expanded complex)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR044434|interpro:IPR046341|rcsb pdb:2LV9|rcsb pdb:4L58|rcsb pdb:5HT6|refseq:NP_061152.3|refseq:NP_891847.1|refseq:XP_005250550.1|refseq:XP_011514702.1|panther:PTHR46462(orthology-group)"	"interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR022866|refseq:WP_002213054.1|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009408""(response to heat)|interpro:IPR036623|refseq:YP_002346465.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:R88sB8694YH12wYZLv4PLcpqegU9606	rogid:+HCTn04AY15SicugA6Q3VBpkSQU632	intact-crc:9DCED84CF3186A6A|rigid:D2j56jo+esW5I8PWJRqUYLdqVXM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2796107	uniprotkb:A0A2U2GXR2	-	intact:EBI-2843146|uniprotkb:Q74PJ2|uniprotkb:Q0WB19|uniprotkb:Q7CL49|uniprotkb:A0A3N4AWB6|uniprotkb:A0A384LGR5	psi-mi:q6p491_human(display_short)|psi-mi:EBI-2796107(display_long)	psi-mi:a0a2u2gxr2_yerpe(display_long)|uniprotkb:YPO3634(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859174|imex:IM-13779-6393	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6P491(uniprot-removed-ac)	"interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002210044.1|refseq:YP_002348519.1|interpro:IPR050107"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:J+WSGnBdkicCNERBIkk/oDw6qcU632	intact-crc:8E629EECB0E990AA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9RID8	intact:EBI-2796107	intact:EBI-2859217|uniprotkb:A0A3G5LBF7|uniprotkb:A0A384LNJ8|uniprotkb:Q7BTU6|uniprotkb:A0A2S9PDW1|uniprotkb:A0A380PG85	-	psi-mi:q9rid8_yerpe(display_long)|uniprotkb:YPMT1.33(locus name)	psi-mi:q6p491_human(display_short)|psi-mi:EBI-2796107(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859214|imex:IM-13779-6396	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002214134.1|refseq:NP_857670.1|interpro:IPR003223(Flagellin phase1 repressor)|refseq:NP_395371.1|go:""GO:0003700""(DNA-binding transcription factor activity)"	uniprotkb:Q6P491(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Gai8ohATJMOb+TpT/VpPGU9fdDw632	-	intact-crc:0A2B0D8ABE01A421	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2796107	uniprotkb:A0A2S9PKV8	-	intact:EBI-2859198|uniprotkb:Q74WD4|uniprotkb:Q0WHK6|uniprotkb:Q7CH84|uniprotkb:A0A384KBV6	psi-mi:q6p491_human(display_short)|psi-mi:EBI-2796107(display_long)	psi-mi:a0a2s9pkv8_yerpe(display_long)|uniprotkb:YPO1194(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859195|imex:IM-13779-6397	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6P491(uniprot-removed-ac)	"interpro:IPR001763(Rhodanese-like)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|refseq:WP_002210799.1|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0016784""(3-mercaptopyruvate sulfurtransferase activity)|interpro:IPR036873|refseq:YP_002346232.1|interpro:IPR045078|panther:PTHR11364(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:tC9S/oaqk3d0afXfuawLwoksqPQ632	intact-crc:3E68D7C5F243C590	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2796107	uniprotkb:A0A2U2H346	-	intact:EBI-2849136|uniprotkb:Q74TG8|uniprotkb:A0A0H2W5H4|uniprotkb:Q0WEC0|uniprotkb:Q7CIT1|uniprotkb:A0A384KWM5	psi-mi:q6p491_human(display_short)|psi-mi:EBI-2796107(display_long)	psi-mi:a0a2u2h346_yerpe(display_long)|uniprotkb:YPO2403(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859181|imex:IM-13779-6398	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6P491(uniprot-removed-ac)	"interpro:IPR010231(SUF system FeS cluster assembly, SufB)|interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|refseq:WP_002211808.1|go:""GO:0016226""(iron-sulfur cluster assembly)|interpro:IPR037284|refseq:YP_002347368.1|interpro:IPR045595"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:DkCekEHB1T0D0zddmetEadbmVDk632	intact-crc:C7B56136CEB5CB48	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B1T4	intact:EBI-2796107	intact:EBI-2853134|uniprotkb:Q74US9|uniprotkb:Q7CHW3|uniprotkb:Q0WG18	-	psi-mi:a0a3n4b1t4_yerpe(display_long)|uniprotkb:pabB(gene name)|psi-mi:pabB(display_short)|uniprotkb:YPO1773(locus name)	psi-mi:q6p491_human(display_short)|psi-mi:EBI-2796107(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859188|imex:IM-13779-6394	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR019999|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR015890(Chorismate binding, C-terminal)|interpro:IPR005802(Para-aminobenzoate synthase, component I)|refseq:WP_002211081.1|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0009396""(folic acid-containing compound biosynthetic process)|go:""GO:0016829""(lyase activity)|go:""GO:0046820""(4-amino-4-deoxychorismate synthase activity)|refseq:YP_002346770.1|panther:PTHR11236(orthology-group)"	uniprotkb:Q6P491(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fkSqWMkWrOvBbNXuB2JurPa96zg632	-	intact-crc:6FCCBD0B54038A25	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WKG1	intact:EBI-2796107	intact:EBI-2855083|uniprotkb:Q74Y36|uniprotkb:A0A0H2W137|uniprotkb:A0A3N4AZM6|uniprotkb:Q7CFW7|uniprotkb:A0A384L9U0	-	psi-mi:q0wkg1_yerpe(display_long)|uniprotkb:YPO0141(locus name)	psi-mi:q6p491_human(display_short)|psi-mi:EBI-2796107(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859207|imex:IM-13779-6395	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|refseq:WP_002208909.1|go:""GO:0046872""(metal ion binding)|interpro:IPR050155|interpro:IPR036412|refseq:YP_002345227.1"	uniprotkb:Q6P491(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:C2n5rHIofpB8tAA4iKdS/lm5nZ4632	-	intact-crc:0885F29F6E39CF33	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q70EL1	uniprotkb:Q7CGI0	intact:EBI-946185|intact:EBI-2798236|uniprotkb:B9ZVM1|uniprotkb:A1L4Q4|uniprotkb:A3KFK3|uniprotkb:A3KFK5|uniprotkb:A3KFK6|uniprotkb:A3KFK7|uniprotkb:A6PVS4|uniprotkb:A6PVS5|uniprotkb:A6PVS6|uniprotkb:A6PVS7|uniprotkb:B3KVY1|uniprotkb:Q5F2F4|uniprotkb:Q6ZSP1|uniprotkb:Q6ZSR1|uniprotkb:Q6ZTM0|uniprotkb:Q8N1X2|uniprotkb:Q6P1N6|ensembl:ENSP00000345216.4|ensembl:ENSP00000510226.1	intact:EBI-2840021|uniprotkb:Q74RN4	psi-mi:ubp54_human(display_long)|uniprotkb:C10orf29(gene name synonym)|uniprotkb:USP54(gene name)|psi-mi:USP54(display_short)|uniprotkb:Ubiquitin-specific peptidase 54(gene name synonym)	psi-mi:ftsp_yerpe(display_long)|uniprotkb:ftsP(gene name)|psi-mi:ftsP(display_short)|uniprotkb:YPO0673(locus name)|uniprotkb:YP_2989(locus name)|uniprotkb:y3504(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859250|imex:IM-13779-6403	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_689799.3|refseq:NP_001307366.1|ensembl:ENSG00000166348.20(gene)|ensembl:ENST00000339859.8(transcript)|ensembl:ENST00000687698.1(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0016579""(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|interpro:IPR038765|interpro:IPR052398|mint:Q70EL1|rcsb pdb:8C61|refseq:XP_016871263.1|refseq:XP_016871264.1|refseq:XP_016871265.1|refseq:XP_016871266.1|panther:PTHR22975(orthology-group)"	"refseq:YP_002345741.1|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR008972(Cupredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR026589|refseq:WP_002212176.1|go:""GO:0005507""(copper ion binding)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|interpro:IPR045087|panther:PTHR11709(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TwMLO8uUiZ6onr+jyUz5D6qwZ1g9606	rogid:JQTwQ8R/Yza07pQepCvAhD8UkWA632	intact-crc:209502511C4D0623|rigid:GPZYaFqHG4IwBoFVdiBJstZxMkU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6P0P0	uniprotkb:A0A2S9PFD7	intact:EBI-2825917	intact:EBI-2859267|uniprotkb:Q7CJH0|uniprotkb:Q0WCQ3	psi-mi:q6p0p0_human(display_long)|uniprotkb:MBD6(gene name)|psi-mi:MBD6(display_short)	psi-mi:a0a2s9pfd7_yerpe(display_long)|uniprotkb:cysW(gene name)|psi-mi:cysW(display_short)|uniprotkb:YPO3013(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859264|imex:IM-13779-6401	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001739(Methyl-CpG DNA binding)|refseq:NP_443129.3|interpro:IPR016177(DNA-binding, integrase-type)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|interpro:IPR011866(Sulphate ABC transporter, permease protein CysW)|interpro:IPR005667(Sulphate ABC transporter permease protein 2)|refseq:WP_002208510.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015419""(ABC-type sulfate transporter activity)|interpro:IPR035906|refseq:YP_002347935.1|panther:PTHR30406(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5PNUdeKqnHsVy1Xy6dVNeDYjQkg9606	rogid:JwGXgWwCj+0vH4Ju43jH9aNfHSY632	intact-crc:B12F540A72131539|rigid:Im3l0AgaCCoqFeEjYs0y2AuU7co	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92619	uniprotkb:Q8D0R5	intact:EBI-2825900|uniprotkb:Q9GJP1|uniprotkb:Q9MY24|uniprotkb:Q9GJP0|uniprotkb:Q7LE26|uniprotkb:Q8HX84|uniprotkb:Q86WS1|uniprotkb:Q9GJN9|uniprotkb:Q6P189|uniprotkb:B4DTS4|uniprotkb:F6QP70|ensembl:ENSP00000316772.2	intact:EBI-2850346|uniprotkb:Q74T91	psi-mi:hmha1_human(display_long)|uniprotkb:ARHGAP45(gene name)|psi-mi:ARHGAP45(display_short)|uniprotkb:HMHA1(gene name synonym)|uniprotkb:KIAA0223(gene name synonym)	psi-mi:q8d0r5_yerpe(display_long)|uniprotkb:cpsG(gene name)|psi-mi:cpsG(display_short)|uniprotkb:y1710(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859257|imex:IM-13779-6404	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036424.2|refseq:NP_001245257.1|refseq:NP_001269263.1|refseq:NP_001269264.1|ensembl:ENSG00000180448.11(gene)|ensembl:ENST00000313093.7(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0046872""(metal ion binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0051058""(negative regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR046349|interpro:IPR051025|interpro:IPR054713|rcsb pdb:3D25|rcsb pdb:3FT3|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|panther:PTHR15228(orthology-group)"	"interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016868""(intramolecular phosphotransferase activity)|interpro:IPR036900"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nRGrHrWZk1fyrQODPbmqj6+pJcc9606	rogid:z2kz1BX3Sd7E73WGqRSF6X0AGrM632	intact-crc:744BBE1C62428C9E|rigid:7bP8OZubghZ+1f0ZZgRh93R8w3w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCP4	intact:EBI-2796107	intact:EBI-2859224|uniprotkb:Q0WCX8	-	psi-mi:pdxj_yerpe(display_long)|uniprotkb:pdxJ(gene name)|psi-mi:pdxJ(display_short)|uniprotkb:YPO2930(locus name)|uniprotkb:y1300(locus name)|uniprotkb:YP_2525(locus name)	psi-mi:q6p491_human(display_short)|psi-mi:EBI-2796107(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859229|imex:IM-13779-6399	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004569(""Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ"")|rcsb pdb:3F4N|refseq:WP_002211569.1|go:""GO:0005829""(cytosol)|go:""GO:0008615""(pyridoxine biosynthetic process)|go:""GO:0033856""(pyridoxine 5'-phosphate synthase activity)|interpro:IPR036130|refseq:YP_002347860.1|panther:PTHR30456(orthology-group)"	uniprotkb:Q6P491(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:V3zZ7N7jjvgdZvAJZUyN3RJoUiQ632	-	intact-crc:A5545CDFCC911C59	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2825867	uniprotkb:Q8ZJ02	-	intact:EBI-2855503|uniprotkb:Q0WJX8|uniprotkb:Q7CKN8|uniprotkb:Q74XE7	psi-mi:q6p491_human(display_short)|psi-mi:EBI-2825867(display_long)	"psi-mi:rhab_yerpe(display_long)|uniprotkb:rhaB(gene name)|psi-mi:rhaB(display_short)|uniprotkb:Rhamnulose kinase(gene name synonym)|uniprotkb:YPO0330(locus name)|uniprotkb:y0587(locus name)|uniprotkb:YP_0485(locus name)|uniprotkb:L-rhamnulose 1-kinase(gene name synonym)|uniprotkb:""ATP:L-rhamnulose phosphotransferase""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859236|imex:IM-13779-6402	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6P447(uniprot-removed-ac)	"interpro:IPR018485|interpro:IPR018484|interpro:IPR013449(Rhamnulokinase)|interpro:IPR000577(Carbohydrate kinase, FGGY)|refseq:WP_002209105.1|go:""GO:0004370""(glycerol kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008993""(rhamnulokinase activity)|go:""GO:0019301""(rhamnose catabolic process)|interpro:IPR043129|refseq:YP_002345410.1|panther:PTHR10196(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:lL9J4K2xcNV9zW+r3/RgTvxRYeQ632	intact-crc:E922A5DFCD4C222B	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1M8	uniprotkb:Q70EL1	intact:EBI-2843956	intact:EBI-946185|intact:EBI-2798236|uniprotkb:B9ZVM1|uniprotkb:A1L4Q4|uniprotkb:A3KFK3|uniprotkb:A3KFK5|uniprotkb:A3KFK6|uniprotkb:A3KFK7|uniprotkb:A6PVS4|uniprotkb:A6PVS5|uniprotkb:A6PVS6|uniprotkb:A6PVS7|uniprotkb:B3KVY1|uniprotkb:Q5F2F4|uniprotkb:Q6ZSP1|uniprotkb:Q6ZSR1|uniprotkb:Q6ZTM0|uniprotkb:Q8N1X2|uniprotkb:Q6P1N6|ensembl:ENSP00000345216.4|ensembl:ENSP00000510226.1	psi-mi:q8d1m8_yerpe(display_long)|uniprotkb:y0257(locus name)	psi-mi:ubp54_human(display_long)|uniprotkb:C10orf29(gene name synonym)|uniprotkb:USP54(gene name)|psi-mi:USP54(display_short)|uniprotkb:Ubiquitin-specific peptidase 54(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859243|imex:IM-13779-6400	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)|interpro:IPR050708	"refseq:NP_689799.3|refseq:NP_001307366.1|ensembl:ENSG00000166348.20(gene)|ensembl:ENST00000339859.8(transcript)|ensembl:ENST00000687698.1(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0016579""(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|interpro:IPR038765|interpro:IPR052398|mint:Q70EL1|rcsb pdb:8C61|refseq:XP_016871263.1|refseq:XP_016871264.1|refseq:XP_016871265.1|refseq:XP_016871266.1|panther:PTHR22975(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CV6eFVldIgYFQRKvjlqv9/IE4do632	rogid:TwMLO8uUiZ6onr+jyUz5D6qwZ1g9606	intact-crc:81B7D2FFC1AB9D2E|rigid:pFKvdqmgWyP6PlPj2O/IAMAY8u4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6P0P0	uniprotkb:Q0WJ53	intact:EBI-2825917	intact:EBI-2841146|uniprotkb:A0A0H2W7L9|uniprotkb:Q74RT3|uniprotkb:Q7CGF0|uniprotkb:A0A380PMR6	psi-mi:q6p0p0_human(display_long)|uniprotkb:MBD6(gene name)|psi-mi:MBD6(display_short)	psi-mi:q0wj53_yerpe(display_long)|uniprotkb:YPO0616(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859275|imex:IM-13779-6405	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001739(Methyl-CpG DNA binding)|refseq:NP_443129.3|interpro:IPR016177(DNA-binding, integrase-type)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)"	"refseq:YP_002345685.1|interpro:IPR002772(Glycoside hydrolase, family 3, C-terminal)|interpro:IPR001764(Glycoside hydrolase, family 3, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR026891|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036881|interpro:IPR036962|refseq:WP_002210379.1|interpro:IPR051915"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5PNUdeKqnHsVy1Xy6dVNeDYjQkg9606	rogid:NIeb7qLRqloPp0rZ/Uu04q0TwMU632	intact-crc:7CE35CEF69A5D09D|rigid:yKfycypf4SNmwVTqG+AWwbnMfR0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKW7	uniprotkb:Q9NVV2	intact:EBI-2845318	intact:EBI-2859285|uniprotkb:Q6NSX4|ensembl:ENSP00000386230.2	psi-mi:q8ckw7_yerpe(display_long)|uniprotkb:y2698(locus name)	psi-mi:cs073_human(display_long)|uniprotkb:C19orf73(gene name)|psi-mi:C19orf73(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859282|imex:IM-13779-6407	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002231240.1|interpro:IPR028244|interpro:IPR018769|interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)	refseq:NP_060581.2|ensembl:ENSG00000221916.4(gene)|ensembl:ENST00000408991.4(transcript)|interpro:IPR040779	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Nrvz9YxMF2TgzN5e3ZNazVacK34632	rogid:aeYwmHW79+pLA95JO+4vK7/8SSk9606	intact-crc:792CBA6C3C066237|rigid:W56glEssdinTEUcgD7Wpll12YvE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2859303	uniprotkb:Q8ZJF3	-	intact:EBI-2850095|uniprotkb:Q0WKE6	psi-mi:sphar_human(display_short)|psi-mi:EBI-2859303(display_long)|uniprotkb:SPHAR(gene name)|psi-mi:SPHAR(display_short)|uniprotkb:S-phase response protein(gene name synonym)	psi-mi:gph_yerpe(display_long)|uniprotkb:gph(gene name)|psi-mi:gph(display_short)|uniprotkb:YPO0156(locus name)|uniprotkb:y3939(locus name)|uniprotkb:YP_0158(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859309|imex:IM-13779-6406	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q15513(uniprot-removed-ac)	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|interpro:IPR037512|refseq:WP_002208892.1|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006281""(DNA repair)|go:""GO:0008967""(phosphoglycolate phosphatase activity)|go:""GO:0046295""(glycolate biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR036412|interpro:IPR041492|refseq:YP_002345242.1|interpro:IPR050155|panther:PTHR43434(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bEfosjqXtGkl5Ihd9Dd56pAdnQ09606	rogid:n2m9iPEoLBOpfauijcWx/W/lq+M632	intact-crc:9ABB136CC5CC4C2E|rigid:9NRv+nCDu7yQtgFofnVGgz1iqI4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2859294	uniprotkb:Q7CIZ3	-	intact:EBI-2852946|uniprotkb:Q74UE1	psi-mi:q6nsf3_human(display_short)|psi-mi:EBI-2859294(display_long)	psi-mi:bgal_yerpe(display_long)|uniprotkb:lacZ(gene name)|psi-mi:lacZ(display_short)|uniprotkb:Lactase(gene name synonym)|uniprotkb:YPO1654(locus name)|uniprotkb:y1817(locus name)|uniprotkb:YP_1785(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859296|imex:IM-13779-6408	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q6NSF3(uniprot-removed-ac)	"interpro:IPR050347|interpro:IPR008979(Galactose-binding like)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR014718(Glycoside hydrolase-type carbohydrate-binding, subgroup)|interpro:IPR006101(Glycoside hydrolase, family 2)|interpro:IPR023232|interpro:IPR023933|interpro:IPR023230|interpro:IPR004199(Glycoside hydrolase, family 42, domain 5)|interpro:IPR006102(Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich)|interpro:IPR006104(Glycoside hydrolase family 2, carbohydrate-binding)|interpro:IPR006103(Glycoside hydrolase family 2, TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002214048.1|interpro:IPR032312|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004565""(beta-galactosidase activity)|go:""GO:0005990""(lactose catabolic process)|go:""GO:0009341""(beta-galactosidase complex)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036156|refseq:YP_002346664.1|panther:PTHR46323(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:RFOxfJbd+ZN/lJ/fIfkqbMSwF7w632	intact-crc:6F0EF71C5DF959A1	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P51148	uniprotkb:A0A0H2W4I3	intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689.5|ensembl:ENSP00000377440.3|intact:EBI-21355794	intact:EBI-2859355	psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym)	psi-mi:a0a0h2w4i3_yerpe(display_long)|uniprotkb:baeS4(gene name)|psi-mi:baeS4(display_short)|uniprotkb:YP_1847(locus name)|uniprotkb:y2308(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859352|imex:IM-13779-6413	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004574.2|refseq:NP_958842.1|refseq:NP_001238968.1|ensembl:ENSG00000108774.15(gene)|ensembl:ENST00000346213.9(transcript)|ensembl:ENST00000393860.7(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0012505""(endomembrane system)|go:""GO:0019003""(GDP binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042470""(melanosome)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51148|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9820960|refseq:XP_011523392.1|refseq:XP_011523393.1|panther:PTHR24073(orthology-group)"	"interpro:IPR050428|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|uniprotkb:A0A2U2H0U9(uniprot-removed-ac)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR006290(Signal transduction histidine kinase, heavy metal sensor)|interpro:IPR036097|interpro:IPR036890"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606	rogid:8DFMrQ+cCcz7yzAotZ3lLq4Qj3Q632	intact-crc:D08E089FDB64AF21|rigid:1v4OMMg7K1rKLN+0Rs6pQjqekzk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B6L0	uniprotkb:P52565	intact:EBI-2843472|uniprotkb:Q74V57|uniprotkb:Q0WG53|uniprotkb:Q7CHU3|uniprotkb:A0A384LQD6	intact:EBI-712693|intact:EBI-718039|intact:EBI-2840752|uniprotkb:A8MXW0|uniprotkb:B4DDD3|uniprotkb:B4DUV9|uniprotkb:B2R5X1|uniprotkb:Q6IBM5|ensembl:ENSP00000269321.7|ensembl:ENSP00000441348.2|ensembl:ENSP00000464205.1	psi-mi:a0a3n4b6l0_yerpe(display_long)|uniprotkb:YPO1735(locus name)	psi-mi:gdir1_human(display_long)|uniprotkb:Rho-GDI alpha(gene name synonym)|uniprotkb:ARHGDIA(gene name)|psi-mi:ARHGDIA(display_short)|uniprotkb:GDIA1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859338|imex:IM-13779-6410	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034040""(ATPase-coupled lipid transmembrane transporter activity)|go:""GO:0055085""(transmembrane transport)|go:""GO:0140359""(ABC-type transporter activity)|refseq:WP_002211045.1|interpro:IPR039421|interpro:IPR036640|refseq:YP_002346735.1|panther:PTHR24221(orthology-group)"	"rcsb pdb:1RHO|rcsb pdb:2BXW|rcsb pdb:2JHS|rcsb pdb:2JHT|rcsb pdb:2JHU|rcsb pdb:2JHV|rcsb pdb:2JHW|rcsb pdb:2JHX|rcsb pdb:2JHY|rcsb pdb:2JHZ|rcsb pdb:2JI0|rcsb pdb:2N80|rcsb pdb:8X8T|reactome:R-HSA-193634|reactome:R-HSA-209563|reactome:R-HSA-8980692|reactome:R-HSA-9013106|ensembl:ENSG00000141522.13(gene)|ensembl:ENST00000269321.12(transcript)|ensembl:ENST00000541078.7(transcript)|ensembl:ENST00000580685.5(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0005094""(Rho GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098693""(regulation of synaptic vesicle cycle)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52565|rcsb pdb:1CC0|rcsb pdb:1FSO|rcsb pdb:1FST|rcsb pdb:1FT0|rcsb pdb:1FT3|rcsb pdb:1HH4|rcsb pdb:1KMT|rcsb pdb:1QVY|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013407|reactome:R-HSA-9013408|refseq:NP_001172006.1|refseq:NP_001172007.1|refseq:NP_001288169.1|refseq:NP_001288170.1|refseq:NP_001288171.1|refseq:NP_001288172.1|refseq:NP_004300.1|efo:""Orphanet:656""|panther:PTHR10980(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ep3J4ZlEy2Z2pYtxMfWUvoNfklU632	rogid:nHmwosTUeo1R72Mp5uHLYdcBofk9606	intact-crc:F9D945529C3D1543|rigid:pM3IvLMQ8KdkndPQun7UHa/gK5Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA76	uniprotkb:P52565	intact:EBI-2846943|uniprotkb:Q0WA76	intact:EBI-712693|intact:EBI-718039|intact:EBI-2840752|uniprotkb:A8MXW0|uniprotkb:B4DDD3|uniprotkb:B4DUV9|uniprotkb:B2R5X1|uniprotkb:Q6IBM5|ensembl:ENSP00000269321.7|ensembl:ENSP00000441348.2|ensembl:ENSP00000464205.1	psi-mi:glgx_yerpe(display_long)|uniprotkb:glgX(gene name)|psi-mi:glgX(display_short)|uniprotkb:Limit dextrin alpha-1,6-maltotetraose-hydrolase(gene name synonym)|uniprotkb:YPO3941(locus name)|uniprotkb:YP_3303(locus name)|uniprotkb:y3887(locus name)	psi-mi:gdir1_human(display_long)|uniprotkb:Rho-GDI alpha(gene name synonym)|uniprotkb:ARHGDIA(gene name)|psi-mi:ARHGDIA(display_short)|uniprotkb:GDIA1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859345|imex:IM-13779-6411	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR022844|interpro:IPR011837(Glycogen debranching enzyme GlgX)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR040784|go:""GO:0004133""(obsolete glycogen debranching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005980""(glycogen catabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_002209499.1|interpro:IPR044505|refseq:YP_002348812.1|panther:PTHR43002(orthology-group)"	"rcsb pdb:1RHO|rcsb pdb:2BXW|rcsb pdb:2JHS|rcsb pdb:2JHT|rcsb pdb:2JHU|rcsb pdb:2JHV|rcsb pdb:2JHW|rcsb pdb:2JHX|rcsb pdb:2JHY|rcsb pdb:2JHZ|rcsb pdb:2JI0|rcsb pdb:2N80|rcsb pdb:8X8T|reactome:R-HSA-193634|reactome:R-HSA-209563|reactome:R-HSA-8980692|reactome:R-HSA-9013106|ensembl:ENSG00000141522.13(gene)|ensembl:ENST00000269321.12(transcript)|ensembl:ENST00000541078.7(transcript)|ensembl:ENST00000580685.5(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0005094""(Rho GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098693""(regulation of synaptic vesicle cycle)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52565|rcsb pdb:1CC0|rcsb pdb:1FSO|rcsb pdb:1FST|rcsb pdb:1FT0|rcsb pdb:1FT3|rcsb pdb:1HH4|rcsb pdb:1KMT|rcsb pdb:1QVY|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013407|reactome:R-HSA-9013408|refseq:NP_001172006.1|refseq:NP_001172007.1|refseq:NP_001288169.1|refseq:NP_001288170.1|refseq:NP_001288171.1|refseq:NP_001288172.1|refseq:NP_004300.1|efo:""Orphanet:656""|panther:PTHR10980(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8sHtj0obGqvrIdGE1JWk8okcbRM632	rogid:nHmwosTUeo1R72Mp5uHLYdcBofk9606	intact-crc:9B18683E02F44AFF|rigid:Eac7OX+OG3y++62Vb6GcAq0Yu4o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6N0B2	uniprotkb:A0A5P8YED3	intact:EBI-2859319	intact:EBI-2854280|uniprotkb:Q0WHC6|uniprotkb:Q7CHD9|uniprotkb:A0A384L0S4	psi-mi:q6n0b2_human(display_long)|uniprotkb:DKFZp686G18136(gene name)|psi-mi:DKFZp686G18136(display_short)	psi-mi:a0a5p8yed3_yerpe(display_long)|uniprotkb:YPO1286(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859316|imex:IM-13779-6409	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001985(S-adenosylmethionine decarboxylase)|interpro:IPR016067(S-adenosylmethionine decarboxylase, core)|interpro:IPR018166|refseq:NP_001625.2|go:""GO:0004014""(adenosylmethionine decarboxylase activity)|go:""GO:0006597""(spermine biosynthetic process)|go:""GO:0008295""(spermidine biosynthetic process)|interpro:IPR048283"	interpro:IPR052572|interpro:IPR005358(Protein of unknown function UPF0153)|refseq:WP_002208811.1|refseq:YP_002346312.1|panther:PTHR36931(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:X8GJXlWjc9wCFyUSARh52FdmfMk9606	rogid:xi1BijFluPDXuPfEHIwAzy+vb5s632	intact-crc:B5CEF0EFAFC0D332|rigid:Ub3TK5+MPgrgfqjatNQtssxQe58	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6L5J4	uniprotkb:Q8CK83	intact:EBI-2859327	intact:EBI-2851851|uniprotkb:Q74QS6	psi-mi:q6l5j4_human(display_long)|uniprotkb:FPRL2(gene name)|psi-mi:FPRL2(display_short)|uniprotkb:hCG_91958(orf name)	psi-mi:q8ck83_yerpe(display_long)|uniprotkb:accC1(gene name)|psi-mi:accC1(display_short)|uniprotkb:YP_3384(locus name)|uniprotkb:y4042(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859331|imex:IM-13779-6412	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011524989.1|refseq:NP_002021.3|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000826(Formyl/methionyl peptide receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)"	"interpro:IPR011761(ATP-grasp fold)|go:""GO:0005524""(ATP binding)|go:""GO:0016874""(ligase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR052032"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zMODy8OpAaXTq9mUW80J9jkNfiA9606	rogid:zWNetqBcgNgoffpGm1WuBpGKZiA632	intact-crc:0A44063B849F2A2C|rigid:CMqJ7SQ5JxpAW20bXEDu6KzhW5Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ73	uniprotkb:Q6EI07	intact:EBI-2856761|uniprotkb:Q74XL3|uniprotkb:Q0WK57|uniprotkb:Q7CKS9	intact:EBI-2859379	psi-mi:actp_yerpe(display_long)|uniprotkb:actP(gene name)|psi-mi:actP(display_short)|uniprotkb:Acetate permease(gene name synonym)|uniprotkb:Acetate transporter ActP(gene name synonym)|uniprotkb:YPO0251(locus name)|uniprotkb:y0508(locus name)|uniprotkb:YP_0404(locus name)	psi-mi:q6ei07_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859382|imex:IM-13779-6414	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014083(Cation/acetate symporter ActP)|interpro:IPR001734(Na+/solute symporter)|interpro:IPR018212|interpro:IPR050277|refseq:WP_002209029.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006814""(sodium ion transport)|go:""GO:0006847""(plasma membrane acetate transport)|go:""GO:0015123""(acetate transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|go:""GO:0043879""(glycolate transmembrane transporter activity)|interpro:IPR038377|refseq:YP_002345331.1|panther:PTHR48086(orthology-group)"	"go:""GO:0008168""(methyltransferase activity)|go:""GO:0032259""(methylation)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7/16s2sdy7eGyVVq+3+pmDS71Kc632	rogid:FFUxXNlFtPXg5mPIh0lqP1FbvDA9606	intact-crc:8E9E2DE5F7DD863B|rigid:873pXVGNU/gVly0uCJgiZwD2KP8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q659B4	uniprotkb:A0A2U2H077	intact:EBI-2859396	intact:EBI-2841812|uniprotkb:Q74VJ9|uniprotkb:A0A384LD89|uniprotkb:Q0WHC7|uniprotkb:Q7CHD8|uniprotkb:A0A380PPP8	psi-mi:q659b4_human(display_long)|uniprotkb:DKFZp667O055(gene name)|psi-mi:DKFZp667O055(display_short)	psi-mi:a0a2u2h077_yerpe(display_long)|uniprotkb:mtr(gene name)|psi-mi:mtr(display_short)|uniprotkb:YPO1285(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859400|imex:IM-13779-6417	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR018097|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0005509""(calcium ion binding)|interpro:IPR052235|interpro:IPR049883"	"interpro:IPR018227|interpro:IPR013059(Tryptophan/tyrosine transporter)|interpro:IPR006311(Twin-arginine translocation pathway signal)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005886""(plasma membrane)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|refseq:YP_002346311.1|refseq:WP_002208812.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zWFMAogkeO30Sd5uCmklucmk5iw9606	rogid:M4JTYX328BR2JznjfkTVzEKmmW4632	intact-crc:044F2AF94F1D2BC7|rigid:4JWR+3o/ztlM6MZKKVdp4f0OUoE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50897	uniprotkb:A0A380PGX5	intact:EBI-1237011|intact:EBI-2859371|uniprotkb:Q6FGQ4|uniprotkb:B4DY24|ensembl:ENSP00000432053.1|ensembl:ENSP00000493153.1	intact:EBI-2859364|uniprotkb:Q0WA59|uniprotkb:Q7CFZ6|uniprotkb:A0A384L997	psi-mi:ppt1_human(display_long)|uniprotkb:PPT1(gene name)|psi-mi:PPT1(display_short)|uniprotkb:PPT(gene name synonym)|uniprotkb:Palmitoyl-protein hydrolase 1(gene name synonym)|uniprotkb:CLN1(gene name synonym)	psi-mi:a0a380pgx5_yerpe(display_long)|uniprotkb:Transcriptional regulatory protein OmpR(gene name synonym)|uniprotkb:YPO3958(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859368|imex:IM-13779-6416	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:228329""|ensembl:ENSG00000131238.18(gene)|ensembl:ENST00000529905.5(transcript)|ensembl:ENST00000642050.2(transcript)|go:""GO:0002084""(protein depalmitoylation)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006897""(endocytosis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006907""(pinocytosis)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0007269""(neurotransmitter secretion)|go:""GO:0007399""(nervous system development)|go:""GO:0007420""(brain development)|go:""GO:0007601""(visual perception)|go:""GO:0007625""(grooming behavior)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008306""(associative learning)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0008474""(""palmitoyl-(protein) hydrolase activity"")|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0030149""(sphingolipid catabolic process)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031579""(membrane raft organization)|go:""GO:0034164""(negative regulation of toll-like receptor 9 signaling pathway)|go:""GO:0035727""(lysophosphatidic acid binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045121""(membrane raft)|go:""GO:0046949""(fatty-acyl-CoA biosynthetic process)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048666""(neuron development)|go:""GO:0050803""(regulation of synapse structure or activity)|go:""GO:0052816""(long-chain fatty acyl-CoA hydrolase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0120146""(sulfatide binding)|interpro:IPR002472(Palmitoyl protein thioesterase)|interpro:IPR029058|mint:P50897|rcsb pdb:3GRO|reactome:R-HSA-75105|refseq:NP_000301.1|refseq:NP_001136076.1|panther:PTHR11247(orthology-group)"	"interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR039420|refseq:WP_002209516.1|go:""GO:0000156""(phosphorelay response regulator activity)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0032993""(protein-DNA complex)|interpro:IPR036388|refseq:YP_002348829.1|panther:PTHR48111(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2G1ae6m4OZsMiRzro/2JmWiOOMA9606	rogid:ga2AV0D49GvY1GxS4xAokS7Hyq4632	intact-crc:DBC5F9B116087D1D|rigid:dKet/h5M/Gzg9jh1Rfd8AhYDGAg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17778	uniprotkb:Q659D1	intact:EBI-2842665|uniprotkb:O68701	intact:EBI-2815376	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	psi-mi:q659d1_human(display_long)|uniprotkb:DKFZp434J052(gene name)|psi-mi:DKFZp434J052(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859389|imex:IM-13779-6415	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"interpro:IPR024858|go:""GO:0005801""(cis-Golgi network)|interpro:IPR043937|interpro:IPR043976"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	rogid:gZHSNPZc86hPqcMK3haKL1B4uBM9606	intact-crc:8C5B37BA9891CCF7|rigid:Z1FcvmZ2bw6ijDumA8Kpjqf/NH8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17778	uniprotkb:P49756	intact:EBI-2842665|uniprotkb:O68701	intact:EBI-2211856|ensembl:ENSP00000261973.7|ensembl:ENSP00000431150.1|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859436|imex:IM-13779-6419	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"ensembl:ENSG00000119707.14(gene)|ensembl:ENST00000261973.12(transcript)|ensembl:ENST00000527432.5(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0042981""(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|interpro:IPR052768|mint:P49756|rcsb pdb:3V53|reactome:R-HSA-72163|refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|panther:PTHR18806(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606	intact-crc:687BA16311219B62|rigid:tXAFpUQnne0jeGBI2HKge9sM8+U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W496	uniprotkb:Q64F87	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	intact:EBI-2802835	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	psi-mi:q64f87_human(display_long)|uniprotkb:TCIRG1(gene name)|psi-mi:TCIRG1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859407|imex:IM-13779-6420	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0033179""(proton-transporting V-type ATPase, V0 domain)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	rogid:O2weW43Gy9rOGzpeBtv4Ak+TKDE9606	intact-crc:2477F77A91557BBB|rigid:731Tf+lOSHgK/E9aBLq7cJZtj6w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2859414	uniprotkb:A0A2U2GZB5	-	intact:EBI-2846673|uniprotkb:Q74QD5|uniprotkb:Q0WII4|uniprotkb:Q7CGV8|uniprotkb:A0A3N4B688|uniprotkb:A0A384LH97	psi-mi:q63z42_human(display_short)|psi-mi:EBI-2859414(display_long)	psi-mi:a0a2u2gzb5_yerpe(display_long)|uniprotkb:YPO0853(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859416|imex:IM-13779-6418	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q63Z42(uniprot-removed-ac)	"interpro:IPR011683(Glycosyl hydrolase 53)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209898.1|go:""GO:0015926""(glucosidase activity)|refseq:YP_002345904.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	-	rogid:vZspj0o9Xm28cUFYlvj9K2v6gM8632	intact-crc:048B394F76D6BA1B	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IVF1	uniprotkb:Q8ZJ73	intact:EBI-2859446|uniprotkb:A6NMX5|uniprotkb:C9JDI1|uniprotkb:Q5VZW1|ensembl:ENSP00000371126.1	intact:EBI-2856761|uniprotkb:Q74XL3|uniprotkb:Q0WK57|uniprotkb:Q7CKS9	psi-mi:ntm2a_human(display_long)|uniprotkb:NUTM2A(gene name)|psi-mi:NUTM2A(display_short)|uniprotkb:FAM22A(gene name synonym)|uniprotkb:KIAA2020(gene name synonym)	psi-mi:actp_yerpe(display_long)|uniprotkb:actP(gene name)|psi-mi:actP(display_short)|uniprotkb:Acetate permease(gene name synonym)|uniprotkb:Acetate transporter ActP(gene name synonym)|uniprotkb:YPO0251(locus name)|uniprotkb:y0508(locus name)|uniprotkb:YP_0404(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859443|imex:IM-13779-6421	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:213711""|ensembl:ENSG00000184923.12(gene)|ensembl:ENST00000381707.6(transcript)|interpro:IPR024309|interpro:IPR024310|refseq:NP_001009610.1|refseq:NP_001092808.1|refseq:XP_011538424.1|refseq:XP_016872096.1|panther:PTHR22879(orthology-group)"	"interpro:IPR014083(Cation/acetate symporter ActP)|interpro:IPR001734(Na+/solute symporter)|interpro:IPR018212|interpro:IPR050277|refseq:WP_002209029.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006814""(sodium ion transport)|go:""GO:0006847""(plasma membrane acetate transport)|go:""GO:0015123""(acetate transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|go:""GO:0043879""(glycolate transmembrane transporter activity)|interpro:IPR038377|refseq:YP_002345331.1|panther:PTHR48086(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sMSSf4Y4kwELDvPln9Cz1GoduRQ9606	rogid:7/16s2sdy7eGyVVq+3+pmDS71Kc632	intact-crc:85D8240E55932C4A|rigid:SPRNGckPCKV0EcfK4SdFcD260es	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GZX8	uniprotkb:Q8IWT3	intact:EBI-2843751|uniprotkb:Q74V95|uniprotkb:A0A0H2W3N0|uniprotkb:Q7CHR8|uniprotkb:Q0WGN7|uniprotkb:A0A384KT94	intact:EBI-311123|uniprotkb:O75188|uniprotkb:Q68CP2|uniprotkb:Q68D92|uniprotkb:Q8N3W9|uniprotkb:Q9BU56|intact:EBI-2845754|uniprotkb:Q5TCY3|ensembl:ENSP00000252050.4	psi-mi:a0a2u2gzx8_yerpe(display_long)|uniprotkb:YPO1535(locus name)	psi-mi:cul9_human(display_long)|uniprotkb:CUL9(gene name)|psi-mi:CUL9(display_short)|uniprotkb:H7AP1(gene name synonym)|uniprotkb:KIAA0708(gene name synonym)|uniprotkb:UbcH7-associated protein 1(gene name synonym)|uniprotkb:PARC(gene name synonym)|uniprotkb:p53-associated parkin-like cytoplasmic protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859487|imex:IM-13779-6425	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000522(Bacterial transport system permease protein)|refseq:WP_002211881.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR037294|refseq:YP_002346551.1"	"refseq:NP_055904.1|ensembl:ENSG00000112659.14(gene)|ensembl:ENST00000252050.9(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031461""(cullin-RING ubiquitin ligase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR017907|interpro:IPR019559|interpro:IPR021097|interpro:IPR036317|interpro:IPR036388|interpro:IPR044066|interpro:IPR045093|interpro:IPR047560|interpro:IPR047561|interpro:IPR047562|mint:Q8IWT3|rcsb pdb:2JUF|rcsb pdb:8Q7E|rcsb pdb:8Q7H|rcsb pdb:8RHZ|reactome:R-HSA-8951664|panther:PTHR22771(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l+psx95jXdNVBQMnKWDbWE5epic632	rogid:l3eOdyfEVm0PkkDykJXN270o1Kc9606	intact-crc:AFD5647DB082CFB4|rigid:Rg/q9SC61uPnLmWrWwBZL3C+0eU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5TYM6	uniprotkb:Q0WKG1	intact:EBI-2859479|ensembl:ENSP00000356097.2	intact:EBI-2855083|uniprotkb:Q74Y36|uniprotkb:A0A0H2W137|uniprotkb:A0A3N4AZM6|uniprotkb:Q7CFW7|uniprotkb:A0A384L9U0	psi-mi:q5tym6_human(display_long)|uniprotkb:FAM72A(gene name)|psi-mi:FAM72A(display_short)|uniprotkb:RP11-312O7.1-006(orf name)	psi-mi:q0wkg1_yerpe(display_long)|uniprotkb:YPO0141(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859476|imex:IM-13779-6422	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011508267.1|refseq:NP_001304830.1|ensembl:ENSG00000196550.11(gene)|ensembl:ENST00000367129.6(transcript)|go:""GO:0005829""(cytosol)|interpro:IPR026768"	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|refseq:WP_002208909.1|go:""GO:0046872""(metal ion binding)|interpro:IPR050155|interpro:IPR036412|refseq:YP_002345227.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XpD0t9GIP74Fx0kHaK55dmaFIWw9606	rogid:C2n5rHIofpB8tAA4iKdS/lm5nZ4632	intact-crc:03E53945B171E679|rigid:Q4WbuRM426QXggFx8PvynVUVQCw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZU2	uniprotkb:Q92598	intact:EBI-2843382	intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|intact:EBI-25629146|uniprotkb:B4DYH1|ensembl:ENSP00000318687.5|intact:EBI-21353685	psi-mi:q8czu2_yerpe(display_long)|uniprotkb:yapH(gene name)|psi-mi:yapH(display_short)|uniprotkb:y3396(locus name)	psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym)|uniprotkb:Heat shock protein family H member 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859503|imex:IM-13779-6423	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR024973|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0019867""(outer membrane)|interpro:IPR036709|interpro:IPR043990|interpro:IPR050909"	"refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694.20(gene)|ensembl:ENST00000320027.10(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0032991""(protein-containing complex)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0045345""(positive regulation of MHC class I biosynthetic process)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051135""(positive regulation of NK T cell activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453|panther:PTHR45639(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:w2l6qUtIv4INNGQ9HeM84bFptXU632	rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606	intact-crc:4CF697B975201B68|rigid:vr07Kx6+sUMKfO4xxVKi+//ycWE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12899	uniprotkb:Q8D1D4	intact:EBI-2341136|ensembl:ENSP00000331131.5|ensembl:ENSP00000373102.2|ensembl:ENSP00000379806.1|ensembl:ENSP00000389203.2|ensembl:ENSP00000390258.1|ensembl:ENSP00000391879.1|ensembl:ENSP00000392805.2|ensembl:ENSP00000393011.1|ensembl:ENSP00000394371.1|ensembl:ENSP00000394421.1|ensembl:ENSP00000395491.1|ensembl:ENSP00000396188.1|ensembl:ENSP00000398545.1|ensembl:ENSP00000402395.1|ensembl:ENSP00000406707.1|ensembl:ENSP00000407294.2|ensembl:ENSP00000407876.1|ensembl:ENSP00000408233.2|ensembl:ENSP00000409182.1|ensembl:ENSP00000410446.2|ensembl:ENSP00000414248.1|ensembl:ENSP00000415328.1|ensembl:ENSP00000415755.2|ensembl:ENSP00000416737.1|intact:EBI-2802887|uniprotkb:A6NG96|uniprotkb:Q5SRL2	intact:EBI-2859510|uniprotkb:Q74X74	psi-mi:tri26_human(display_long)|uniprotkb:TRIM26(gene name)|psi-mi:TRIM26(display_short)|uniprotkb:RNF95(gene name synonym)|uniprotkb:ZNF173(gene name synonym)|uniprotkb:Zinc finger protein 173(gene name synonym)|uniprotkb:Acid finger protein(gene name synonym)|uniprotkb:RING finger protein 95(gene name synonym)	psi-mi:q8d1d4_yerpe(display_long)|uniprotkb:ftsH(gene name synonym)|uniprotkb:hflB(gene name)|psi-mi:hflB(display_short)|uniprotkb:NCTC5923_00800(orf name)|uniprotkb:YP_0581(locus name)|uniprotkb:y0682(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859515|imex:IM-13779-6424	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137313.15(gene)|ensembl:ENSG00000226060.7(gene)|ensembl:ENSG00000228881.7(gene)|ensembl:ENSG00000230230.7(gene)|ensembl:ENSG00000231002.7(gene)|ensembl:ENSG00000231641.9(gene)|ensembl:ENSG00000234046.7(gene)|ensembl:ENSG00000234127.9(gene)|ensembl:ENST00000327357.9(transcript)|ensembl:ENST00000383607.6(transcript)|ensembl:ENST00000396558.5(transcript)|ensembl:ENST00000415923.6(transcript)|ensembl:ENST00000422349.5(transcript)|ensembl:ENST00000425523.5(transcript)|ensembl:ENST00000425831.5(transcript)|ensembl:ENST00000427535.5(transcript)|ensembl:ENST00000428486.5(transcript)|ensembl:ENST00000432326.5(transcript)|ensembl:ENST00000433314.5(transcript)|ensembl:ENST00000436219.5(transcript)|ensembl:ENST00000437089.5(transcript)|ensembl:ENST00000438384.5(transcript)|ensembl:ENST00000438908.5(transcript)|ensembl:ENST00000439094.6(transcript)|ensembl:ENST00000445259.6(transcript)|ensembl:ENST00000447711.6(transcript)|ensembl:ENST00000450392.5(transcript)|ensembl:ENST00000453195.5(transcript)|ensembl:ENST00000454678.7(transcript)|ensembl:ENST00000455000.6(transcript)|ensembl:ENST00000456093.5(transcript)|ensembl:ENST00000456770.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0045087""(innate immune response)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|interpro:IPR050143|mint:Q12899|reactome:R-HSA-877300|refseq:XP_006715243.1|refseq:NP_001229712.1|refseq:NP_003440.1|refseq:XP_005249434.1|refseq:XP_005249431.1|refseq:XP_005249432.1|refseq:XP_005249433.1|refseq:XP_005249435.1|dip:DIP-52853N|panther:PTHR24103(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR000642(Peptidase M41)|interpro:IPR027417|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0051301""(cell division)|interpro:IPR037219|interpro:IPR041569"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:GPu3YgJ3xR1pN/MM9IKU3unCj1A9606	rogid:hxOQM9f6nYka/fP5Gx5H4wtxKzk632	intact-crc:4FCC531FA691AE29|rigid:rzvFCSWI/jAgHW6MzqP9Sl6KkzA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75911	uniprotkb:Q0WBD0	intact:EBI-2859457|uniprotkb:Q9BUC8|uniprotkb:Q6UY38|uniprotkb:Q5VUY3|uniprotkb:B2R7F3|ensembl:ENSP00000480439.1	intact:EBI-2859467|uniprotkb:Q74X88|uniprotkb:A0A0H2W0V4|uniprotkb:Q7CKK2|uniprotkb:A0A3N4BAJ6|uniprotkb:A0A384LII3	psi-mi:dhrs3_human(display_long)|uniprotkb:DHRS3(gene name)|psi-mi:DHRS3(display_short)|uniprotkb:DD83.1(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:RDH17(gene name synonym)|uniprotkb:Retinol dehydrogenase 17(gene name synonym)|uniprotkb:SDR16C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 16C member 1(gene name synonym)|uniprotkb:UNQ2424/PRO4983(orf name)	"psi-mi:q0wbd0_yerpe(display_long)|uniprotkb:mpl(gene name)|psi-mi:mpl(display_short)|uniprotkb:Murein peptide ligase(gene name synonym)|uniprotkb:""UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase""(gene name synonym)|uniprotkb:YPO3519(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859464|imex:IM-13779-6426	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004744.2|ensembl:ENSG00000162496.10(gene)|ensembl:ENST00000616661.5(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0001523""(retinoid metabolic process)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0004745""(""all-trans-retinol dehydrogenase (NAD+) activity"")|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0007601""(visual perception)|go:""GO:0009055""(electron transfer activity)|go:""GO:0030278""(regulation of ossification)|go:""GO:0042572""(retinol metabolic process)|go:""GO:0042622""(photoreceptor outer segment membrane)|go:""GO:0048385""(regulation of retinoic acid receptor signaling pathway)|go:""GO:0048387""(negative regulation of retinoic acid receptor signaling pathway)|go:""GO:0052650""(""all-trans-retinol dehydrogenase (NADP+) activity"")|go:""GO:0060021""(roof of mouth development)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0060411""(cardiac septum morphogenesis)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|reactome:R-HSA-2187335|reactome:R-HSA-5365859|panther:PTHR24322(orthology-group)"	"interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005757(""UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase"")|interpro:IPR050061|refseq:WP_002210171.1|go:""GO:0005524""(ATP binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0009254""(peptidoglycan turnover)|go:""GO:0016881""(acid-amino acid ligase activity)|go:""GO:0051301""(cell division)|go:""GO:0071555""(cell wall organization)|interpro:IPR036565|interpro:IPR036615|refseq:YP_002348408.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YIN4HeYPO/+Atd8NdkZe9BGNxbw9606	rogid:PMIpfeOKUWuVqagpeeFZ2SWD8rg632	intact-crc:49A29B7F1D5AD528|rigid:QY+342OThl8ooYdgXd54ZQdth3M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA84	uniprotkb:Q12899	intact:EBI-2842602|uniprotkb:Q0WA86	intact:EBI-2341136|ensembl:ENSP00000331131.5|ensembl:ENSP00000373102.2|ensembl:ENSP00000379806.1|ensembl:ENSP00000389203.2|ensembl:ENSP00000390258.1|ensembl:ENSP00000391879.1|ensembl:ENSP00000392805.2|ensembl:ENSP00000393011.1|ensembl:ENSP00000394371.1|ensembl:ENSP00000394421.1|ensembl:ENSP00000395491.1|ensembl:ENSP00000396188.1|ensembl:ENSP00000398545.1|ensembl:ENSP00000402395.1|ensembl:ENSP00000406707.1|ensembl:ENSP00000407294.2|ensembl:ENSP00000407876.1|ensembl:ENSP00000408233.2|ensembl:ENSP00000409182.1|ensembl:ENSP00000410446.2|ensembl:ENSP00000414248.1|ensembl:ENSP00000415328.1|ensembl:ENSP00000415755.2|ensembl:ENSP00000416737.1|intact:EBI-2802887|uniprotkb:A6NG96|uniprotkb:Q5SRL2	psi-mi:capp_yerpe(display_long)|uniprotkb:ppc(gene name)|psi-mi:ppc(display_short)|uniprotkb:YPO3929(locus name)|uniprotkb:y0308(locus name)|uniprotkb:YP_3121(locus name)	psi-mi:tri26_human(display_long)|uniprotkb:TRIM26(gene name)|psi-mi:TRIM26(display_short)|uniprotkb:RNF95(gene name synonym)|uniprotkb:ZNF173(gene name synonym)|uniprotkb:Zinc finger protein 173(gene name synonym)|uniprotkb:Acid finger protein(gene name synonym)|uniprotkb:RING finger protein 95(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859536|imex:IM-13779-6428	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033129|interpro:IPR021135|interpro:IPR018129|interpro:IPR022805|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006107""(oxaloacetate metabolic process)|go:""GO:0008964""(phosphoenolpyruvate carboxylase activity)|go:""GO:0015977""(carbon fixation)|refseq:WP_002209491.1|refseq:YP_002348802.1|panther:PTHR30523(orthology-group)"	"ensembl:ENSG00000137313.15(gene)|ensembl:ENSG00000226060.7(gene)|ensembl:ENSG00000228881.7(gene)|ensembl:ENSG00000230230.7(gene)|ensembl:ENSG00000231002.7(gene)|ensembl:ENSG00000231641.9(gene)|ensembl:ENSG00000234046.7(gene)|ensembl:ENSG00000234127.9(gene)|ensembl:ENST00000327357.9(transcript)|ensembl:ENST00000383607.6(transcript)|ensembl:ENST00000396558.5(transcript)|ensembl:ENST00000415923.6(transcript)|ensembl:ENST00000422349.5(transcript)|ensembl:ENST00000425523.5(transcript)|ensembl:ENST00000425831.5(transcript)|ensembl:ENST00000427535.5(transcript)|ensembl:ENST00000428486.5(transcript)|ensembl:ENST00000432326.5(transcript)|ensembl:ENST00000433314.5(transcript)|ensembl:ENST00000436219.5(transcript)|ensembl:ENST00000437089.5(transcript)|ensembl:ENST00000438384.5(transcript)|ensembl:ENST00000438908.5(transcript)|ensembl:ENST00000439094.6(transcript)|ensembl:ENST00000445259.6(transcript)|ensembl:ENST00000447711.6(transcript)|ensembl:ENST00000450392.5(transcript)|ensembl:ENST00000453195.5(transcript)|ensembl:ENST00000454678.7(transcript)|ensembl:ENST00000455000.6(transcript)|ensembl:ENST00000456093.5(transcript)|ensembl:ENST00000456770.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0045087""(innate immune response)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|interpro:IPR050143|mint:Q12899|reactome:R-HSA-877300|refseq:XP_006715243.1|refseq:NP_001229712.1|refseq:NP_003440.1|refseq:XP_005249434.1|refseq:XP_005249431.1|refseq:XP_005249432.1|refseq:XP_005249433.1|refseq:XP_005249435.1|dip:DIP-52853N|panther:PTHR24103(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:aPbGF+uF/gTYbtmc4Mkr1Ys0jNc632	rogid:GPu3YgJ3xR1pN/MM9IKU3unCj1A9606	intact-crc:7132F0A1A680D8F0|rigid:G8f+RuMrDqWKDHsmO3ua5bWZAII	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5R352	uniprotkb:A0A2U2GZS7	intact:EBI-2859546	intact:EBI-2843433|uniprotkb:Q74W70|uniprotkb:A0A0H2W1T5|uniprotkb:Q7CH58|uniprotkb:A0A3N4B3M4|uniprotkb:A0A384LC90	psi-mi:q5r352_human(display_long)|uniprotkb:PLN(gene name)|psi-mi:PLN(display_short)|uniprotkb:hCG_20805(orf name)	psi-mi:a0a2u2gzs7_yerpe(display_long)|uniprotkb:galB(gene name)|psi-mi:galB(display_short)|uniprotkb:galT(gene name synonym)|uniprotkb:YPO1138(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859543|imex:IM-13779-6429	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002658.1|interpro:IPR005984(Phospholamban)|go:""GO:0001675""(acrosome assembly)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0008542""(visual learning)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0042030""(ATPase inhibitor activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0048738""(cardiac muscle tissue development)|go:""GO:0050802""(circadian sleep/wake cycle, sleep)|go:""GO:0086004""(regulation of cardiac muscle cell contraction)|go:""GO:0086023""(adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:""GO:0086092""(regulation of the force of heart contraction by cardiac conduction)|go:""GO:0090279""(regulation of calcium ion import)|go:""GO:1901077""(regulation of relaxation of muscle)|go:""GO:1902081""(negative regulation of calcium ion import into sarcoplasmic reticulum)"	"interpro:IPR001937(Galactose-1-phosphate uridyl transferase, class I)|interpro:IPR005850(Galactose-1-phosphate uridyl transferase, C-terminal)|interpro:IPR005849(Galactose-1-phosphate uridyl transferase, N-terminal)|interpro:IPR019779|go:""GO:0006012""(galactose metabolic process)|go:""GO:0008108""(""UDP-glucose:hexose-1-phosphate uridylyltransferase activity"")|go:""GO:0008270""(zinc ion binding)|refseq:WP_002210749.1|interpro:IPR036265|refseq:YP_002346178.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ez0SC8EfE4K9O9JI5wNGAHJUXOw9606	rogid:1wWEGW8F2ZvDmG2/gCGCjsXVXE4632	intact-crc:333FB0411DC7D484|rigid:cRmVswF5XtHJuRkzwKomPMI1Eig	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12899	uniprotkb:A0A0H2W3V7	intact:EBI-2341136|ensembl:ENSP00000331131.5|ensembl:ENSP00000373102.2|ensembl:ENSP00000379806.1|ensembl:ENSP00000389203.2|ensembl:ENSP00000390258.1|ensembl:ENSP00000391879.1|ensembl:ENSP00000392805.2|ensembl:ENSP00000393011.1|ensembl:ENSP00000394371.1|ensembl:ENSP00000394421.1|ensembl:ENSP00000395491.1|ensembl:ENSP00000396188.1|ensembl:ENSP00000398545.1|ensembl:ENSP00000402395.1|ensembl:ENSP00000406707.1|ensembl:ENSP00000407294.2|ensembl:ENSP00000407876.1|ensembl:ENSP00000408233.2|ensembl:ENSP00000409182.1|ensembl:ENSP00000410446.2|ensembl:ENSP00000414248.1|ensembl:ENSP00000415328.1|ensembl:ENSP00000415755.2|ensembl:ENSP00000416737.1|intact:EBI-2802887|uniprotkb:A6NG96|uniprotkb:Q5SRL2	intact:EBI-2839946|uniprotkb:A0A384LA47|uniprotkb:Q74UY8|uniprotkb:Q0WFV3|uniprotkb:Q7CHZ9|uniprotkb:A0A5P8YEB4	psi-mi:tri26_human(display_long)|uniprotkb:TRIM26(gene name)|psi-mi:TRIM26(display_short)|uniprotkb:RNF95(gene name synonym)|uniprotkb:ZNF173(gene name synonym)|uniprotkb:Zinc finger protein 173(gene name synonym)|uniprotkb:Acid finger protein(gene name synonym)|uniprotkb:RING finger protein 95(gene name synonym)	psi-mi:a0a0h2w3v7_yerpe(display_long)|uniprotkb:flaV(gene name)|psi-mi:flaV(display_short)|uniprotkb:Flagellar cap protein(gene name synonym)|uniprotkb:flbC(gene name synonym)|uniprotkb:fliD(gene name synonym)|uniprotkb:YPO1841(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859529|imex:IM-13779-6430	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137313.15(gene)|ensembl:ENSG00000226060.7(gene)|ensembl:ENSG00000228881.7(gene)|ensembl:ENSG00000230230.7(gene)|ensembl:ENSG00000231002.7(gene)|ensembl:ENSG00000231641.9(gene)|ensembl:ENSG00000234046.7(gene)|ensembl:ENSG00000234127.9(gene)|ensembl:ENST00000327357.9(transcript)|ensembl:ENST00000383607.6(transcript)|ensembl:ENST00000396558.5(transcript)|ensembl:ENST00000415923.6(transcript)|ensembl:ENST00000422349.5(transcript)|ensembl:ENST00000425523.5(transcript)|ensembl:ENST00000425831.5(transcript)|ensembl:ENST00000427535.5(transcript)|ensembl:ENST00000428486.5(transcript)|ensembl:ENST00000432326.5(transcript)|ensembl:ENST00000433314.5(transcript)|ensembl:ENST00000436219.5(transcript)|ensembl:ENST00000437089.5(transcript)|ensembl:ENST00000438384.5(transcript)|ensembl:ENST00000438908.5(transcript)|ensembl:ENST00000439094.6(transcript)|ensembl:ENST00000445259.6(transcript)|ensembl:ENST00000447711.6(transcript)|ensembl:ENST00000450392.5(transcript)|ensembl:ENST00000453195.5(transcript)|ensembl:ENST00000454678.7(transcript)|ensembl:ENST00000455000.6(transcript)|ensembl:ENST00000456093.5(transcript)|ensembl:ENST00000456770.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0045087""(innate immune response)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|interpro:IPR050143|mint:Q12899|reactome:R-HSA-877300|refseq:XP_006715243.1|refseq:NP_001229712.1|refseq:NP_003440.1|refseq:XP_005249434.1|refseq:XP_005249431.1|refseq:XP_005249432.1|refseq:XP_005249433.1|refseq:XP_005249435.1|dip:DIP-52853N|panther:PTHR24103(orthology-group)"	"refseq:YP_002346835.1|interpro:IPR010809(Flagellar hook-associated 2, C-terminal)|interpro:IPR003481(Flagellar hook-associated protein 2, N-terminal)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0009421""(bacterial-type flagellum filament cap)|go:""GO:0009424""(bacterial-type flagellum hook)|refseq:WP_002211150.1|interpro:IPR040026"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:GPu3YgJ3xR1pN/MM9IKU3unCj1A9606	rogid:y6JIeGlhmIELicCmvORRUOwywBM632	intact-crc:50C91A9FCF8C35A2|rigid:oHffY0Rs90Sx1EkCzjxXUJ0jrzo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLT3	uniprotkb:Q12899	intact:EBI-2845884	intact:EBI-2341136|ensembl:ENSP00000331131.5|ensembl:ENSP00000373102.2|ensembl:ENSP00000379806.1|ensembl:ENSP00000389203.2|ensembl:ENSP00000390258.1|ensembl:ENSP00000391879.1|ensembl:ENSP00000392805.2|ensembl:ENSP00000393011.1|ensembl:ENSP00000394371.1|ensembl:ENSP00000394421.1|ensembl:ENSP00000395491.1|ensembl:ENSP00000396188.1|ensembl:ENSP00000398545.1|ensembl:ENSP00000402395.1|ensembl:ENSP00000406707.1|ensembl:ENSP00000407294.2|ensembl:ENSP00000407876.1|ensembl:ENSP00000408233.2|ensembl:ENSP00000409182.1|ensembl:ENSP00000410446.2|ensembl:ENSP00000414248.1|ensembl:ENSP00000415328.1|ensembl:ENSP00000415755.2|ensembl:ENSP00000416737.1|intact:EBI-2802887|uniprotkb:A6NG96|uniprotkb:Q5SRL2	psi-mi:q8clt3_yerpe(display_long)|uniprotkb:y0272(locus name)	psi-mi:tri26_human(display_long)|uniprotkb:TRIM26(gene name)|psi-mi:TRIM26(display_short)|uniprotkb:RNF95(gene name synonym)|uniprotkb:ZNF173(gene name synonym)|uniprotkb:Zinc finger protein 173(gene name synonym)|uniprotkb:Acid finger protein(gene name synonym)|uniprotkb:RING finger protein 95(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859522|imex:IM-13779-6427	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010657(ImpA, N-terminal)|interpro:IPR017739(Type VI secretion system-associated, VCA0119)	"ensembl:ENSG00000137313.15(gene)|ensembl:ENSG00000226060.7(gene)|ensembl:ENSG00000228881.7(gene)|ensembl:ENSG00000230230.7(gene)|ensembl:ENSG00000231002.7(gene)|ensembl:ENSG00000231641.9(gene)|ensembl:ENSG00000234046.7(gene)|ensembl:ENSG00000234127.9(gene)|ensembl:ENST00000327357.9(transcript)|ensembl:ENST00000383607.6(transcript)|ensembl:ENST00000396558.5(transcript)|ensembl:ENST00000415923.6(transcript)|ensembl:ENST00000422349.5(transcript)|ensembl:ENST00000425523.5(transcript)|ensembl:ENST00000425831.5(transcript)|ensembl:ENST00000427535.5(transcript)|ensembl:ENST00000428486.5(transcript)|ensembl:ENST00000432326.5(transcript)|ensembl:ENST00000433314.5(transcript)|ensembl:ENST00000436219.5(transcript)|ensembl:ENST00000437089.5(transcript)|ensembl:ENST00000438384.5(transcript)|ensembl:ENST00000438908.5(transcript)|ensembl:ENST00000439094.6(transcript)|ensembl:ENST00000445259.6(transcript)|ensembl:ENST00000447711.6(transcript)|ensembl:ENST00000450392.5(transcript)|ensembl:ENST00000453195.5(transcript)|ensembl:ENST00000454678.7(transcript)|ensembl:ENST00000455000.6(transcript)|ensembl:ENST00000456093.5(transcript)|ensembl:ENST00000456770.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0045087""(innate immune response)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|interpro:IPR050143|mint:Q12899|reactome:R-HSA-877300|refseq:XP_006715243.1|refseq:NP_001229712.1|refseq:NP_003440.1|refseq:XP_005249434.1|refseq:XP_005249431.1|refseq:XP_005249432.1|refseq:XP_005249433.1|refseq:XP_005249435.1|dip:DIP-52853N|panther:PTHR24103(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:6TnQPOOe3FeEE1LWQVyzY/Oug6E632	rogid:GPu3YgJ3xR1pN/MM9IKU3unCj1A9606	intact-crc:96262C48A7028C89|rigid:PiMYkpVRkACdDYnyqv8pfSrV0Fw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2826141	uniprotkb:P68587	-	intact:EBI-2844901|uniprotkb:P40295	psi-mi:q5jv94_human(display_short)|psi-mi:EBI-2826141(display_long)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:RP11-111L24.1-004(orf name)	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859554|imex:IM-13779-6431	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q5JV94(uniprot-removed-ac)	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2WJNDbDPvPObjnCLjBw9G2ftUTk9606	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	intact-crc:08A3CA65CB33F573|rigid:+aDV+VVmnRxHE7aONoTNcIiwkPE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A384KHP8	intact:EBI-2859573	intact:EBI-2840740|uniprotkb:Q74S58|uniprotkb:Q0WHX7|uniprotkb:Q7CH24	-	psi-mi:a0a384khp8_yerpe(display_long)|uniprotkb:cutF(gene name)|psi-mi:cutF(display_short)|uniprotkb:nlpE(gene name synonym)|uniprotkb:YPO1067(locus name)	psi-mi:q5jtv9_human(display_short)|psi-mi:EBI-2859573(display_long)|uniprotkb:CEP78(gene name)|psi-mi:CEP78(display_short)|uniprotkb:RP11-336N8.5-004(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859577|imex:IM-13779-6432	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR007298(Copper resistance lipoprotein NlpE)|interpro:IPR033450|interpro:IPR038139|interpro:IPR043176|refseq:YP_002346111.1	uniprotkb:Q5JTV9(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ryLPtdXQoNwxiqxUzYaySoAkJkc632	rogid:bziEOagynomfLeV7jqaQdC+RkjU9606	intact-crc:EC509E92E7F9E6C5|rigid:tFB9tGVrMuMfTrHtmIpy0QTuilE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2826141	uniprotkb:Q8D0D5	-	intact:EBI-2859561|uniprotkb:Q74UK8	psi-mi:q5jv94_human(display_short)|psi-mi:EBI-2826141(display_long)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:RP11-111L24.1-004(orf name)	psi-mi:q8d0d5_yerpe(display_long)|uniprotkb:YP_1704(locus name)|uniprotkb:narX(gene name)|psi-mi:narX(display_short)|uniprotkb:y2351(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859566|imex:IM-13779-6434	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q5JV94(uniprot-removed-ac)	"interpro:IPR029095|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR016380(Signal transduction histidine kinase, nitrate/nitrite-sensing)|interpro:IPR011712(Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR050482|interpro:IPR042295|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0046983""(protein dimerization activity)|interpro:IPR036890"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2WJNDbDPvPObjnCLjBw9G2ftUTk9606	rogid:i/66V4m6OjWd+5sHS3qgQKBuP0M632	intact-crc:5204728DB8EA6E90|rigid:V6C/xb0+Zungko24QB1BbGKx+Q8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14596	uniprotkb:Q7CIC2	intact:EBI-742698|uniprotkb:Q13173|uniprotkb:Q15026|uniprotkb:Q96GB6|uniprotkb:Q9NRF7|uniprotkb:Q5J7Q8|intact:EBI-2859623|ensembl:ENSP00000343479.5|ensembl:ENSP00000466667.1	intact:EBI-2859615|uniprotkb:Q74U47	psi-mi:nbr1_human(display_long)|uniprotkb:Neighbor of BRCA1 gene 1 protein(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 2(gene name synonym)|uniprotkb:Protein 1A1-3B(gene name synonym)|uniprotkb:NBR1(gene name)|psi-mi:NBR1(display_short)|uniprotkb:1A13B(gene name synonym)|uniprotkb:KIAA0049(gene name synonym)|uniprotkb:M17S2(gene name synonym)|uniprotkb:Cell migration-inducing gene 19 protein(gene name synonym)|uniprotkb:MIG19(orf name)	psi-mi:znuc_yerpe(display_long)|uniprotkb:znuC(gene name)|psi-mi:znuC(display_short)|uniprotkb:YPO2060(locus name)|uniprotkb:y2250(locus name)|uniprotkb:YP_1903(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859620|imex:IM-13779-6435	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005890.2|refseq:NP_114068.1|refseq:XP_011523115.1|refseq:NP_001278500.1|refseq:NP_001278501.1|refseq:XP_016880131.1|ensembl:ENSG00000188554.15(gene)|ensembl:ENST00000341165.10(transcript)|ensembl:ENST00000590996.6(transcript)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016604""(nuclear body)|go:""GO:0030500""(regulation of bone mineralization)|go:""GO:0031430""(M band)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043235""(receptor complex)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0051019""(mitogen-activated protein kinase binding)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR032350|interpro:IPR034852|interpro:IPR043145|interpro:IPR053793|mint:Q14596|rcsb pdb:1WJ6|rcsb pdb:2BKF|rcsb pdb:2CP8|rcsb pdb:2G4S|rcsb pdb:2L8J|rcsb pdb:2MGW|rcsb pdb:2MJ5|rcsb pdb:4OLE|reactome:R-HSA-9664873|panther:PTHR20930(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR050153|go:""GO:0005524""(ATP binding)|go:""GO:0010043""(response to zinc ion)|go:""GO:0015633""(ABC-type zinc transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|panther:PTHR42734(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rRlRq4sK4fkVQCliQ68/MIEOX6g9606	rogid:bCxjpWeCg/VUwlIaWYH3ZI3h5tk632	intact-crc:7FC146348B49BD55|rigid:bl+x9lMfMdwl752WIY4crhINk60	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZ71	uniprotkb:A0A380SBN9	intact:EBI-2859587|uniprotkb:A2A398|uniprotkb:A2A397|uniprotkb:Q9NZ73|uniprotkb:Q9H4X6|uniprotkb:Q9BW37|uniprotkb:Q9NX25|uniprotkb:B4DYM3|uniprotkb:Q9H402|uniprotkb:Q9UPR4|uniprotkb:B4DRM5|uniprotkb:B4E3N6|uniprotkb:Q9Y4R6|uniprotkb:Q5JTV4|intact:EBI-3248693|uniprotkb:Q5JTV3|uniprotkb:E1P5J4|uniprotkb:E1P5J5|ensembl:ENSP00000359035.3|intact:EBI-28972964	intact:EBI-2859606|uniprotkb:Q74VS2|uniprotkb:A0A384LDT6|uniprotkb:Q0WH40|uniprotkb:Q7CHI7	psi-mi:rtel1_human(display_long)|uniprotkb:RTEL1(gene name)|psi-mi:RTEL1(display_short)|uniprotkb:C20orf41(gene name synonym)|uniprotkb:KIAA1088(gene name synonym)|uniprotkb:NHL(gene name synonym)|uniprotkb:Novel helicase-like(gene name synonym)	psi-mi:a0a380sbn9_yerpe(display_long)|uniprotkb:alsB(gene name)|psi-mi:alsB(display_short)|uniprotkb:ihb(gene name synonym)|uniprotkb:livR(gene name synonym)|uniprotkb:lrp(gene name synonym)|uniprotkb:oppI(gene name synonym)|uniprotkb:YPO1375(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859584|imex:IM-13779-6433	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000258366.12(gene)|ensembl:ENST00000370018.7(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000732""(DNA strand displacement)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0010569""(regulation of double-strand break repair via homologous recombination)|go:""GO:0016607""(nuclear speck)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031297""(replication fork processing)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0043247""(telomere maintenance in response to DNA damage)|go:""GO:0045910""(negative regulation of DNA recombination)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070182""(DNA polymerase binding)|go:""GO:0090657""(telomeric loop disassembly)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1902990""(mitotic telomere maintenance via semi-conservative replication)|go:""GO:1904355""(positive regulation of telomere capping)|go:""GO:1904358""(positive regulation of telomere maintenance via telomere lengthening)|go:""GO:1904430""(negative regulation of t-circle formation)|go:""GO:1904506""(negative regulation of telomere maintenance in response to DNA damage)|go:""GO:1904535""(positive regulation of telomeric loop disassembly)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR013020(""DNA helicase (DNA repair), Rad3 type"")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|interpro:IPR030845|interpro:IPR045028|interpro:IPR049909|rcsb pdb:7WU8|rcsb pdb:8P8H|rcsb pdb:8YA8|reactome:R-HSA-171319|reactome:R-HSA-2564830|reactome:R-HSA-5693554|refseq:NP_001269938.1|refseq:NP_001269939.1|refseq:NP_057518.1|refseq:NP_116575.3|efo:""Orphanet:1775""|efo:""Orphanet:2032""|efo:""Orphanet:3322""|panther:PTHR11472(orthology-group)|ensembl:ENST00000318100.9|ensembl:ENSP00000322287.5|ensembl:ENST00000360203.11|ensembl:ENSP00000353332.5|ensembl:ENSP00000359035.3|ensembl:ENST00000482936.6|ensembl:ENSP00000457868.2|ensembl:ENST00000508582.7|ensembl:ENSP00000424307.2"	"refseq:YP_002346398.1|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR019888|interpro:IPR019887|interpro:IPR000485(Transcription regulator, AsnC/Lrp)|interpro:IPR011991(Winged helix repressor DNA-binding)|interpro:IPR019885|refseq:WP_002211340.1|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006524""(alanine catabolic process)|go:""GO:0043201""(response to L-leucine)|go:""GO:0043565""(sequence-specific DNA binding)|interpro:IPR036388|interpro:IPR036390|panther:PTHR30154(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6gjiNtZ3d+GnlnJR++7G7yo53fs9606	rogid:UhsFhiqr8/nsqSc1PV5oRdAtSvs632	intact-crc:DC1ECC6CAD4AE0FE|rigid:Kg40HpFG91Cco5d36r5AHLRUGQ8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94760	uniprotkb:Q8ZCT9	intact:EBI-2859658|intact:EBI-4286999|uniprotkb:Q5HYC8|uniprotkb:Q86XK5|ensembl:ENSP00000284031.8	intact:EBI-2844687|uniprotkb:Q0WD28	psi-mi:ddah1_human(display_long)|uniprotkb:DDAH1(gene name)|psi-mi:DDAH1(display_short)|uniprotkb:DDAH(gene name synonym)|uniprotkb:DDAHI(gene name synonym)|uniprotkb:Dimethylargininase-1(gene name synonym)	psi-mi:der_yerpe(display_long)|uniprotkb:der(gene name)|psi-mi:der(display_short)|uniprotkb:engA(gene name synonym)|uniprotkb:GTP-binding protein EngA(gene name synonym)|uniprotkb:YPO2875(locus name)|uniprotkb:y1357(locus name)|uniprotkb:YP_2741(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859655|imex:IM-13779-6439	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036269.1|refseq:NP_001127917.1|refseq:XP_005270767.1|ensembl:ENSG00000153904.21(gene)|ensembl:ENST00000284031.13(transcript)|go:""GO:0000052""(citrulline metabolic process)|go:""GO:0003073""(regulation of systemic arterial blood pressure)|go:""GO:0003824""(catalytic activity)|go:""GO:0005829""(cytosol)|go:""GO:0006525""(arginine metabolic process)|go:""GO:0006527""(arginine catabolic process)|go:""GO:0007263""(nitric oxide mediated signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016403""(dimethylargininase activity)|go:""GO:0016597""(amino acid binding)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046209""(nitric oxide metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1900038""(negative regulation of cellular response to hypoxia)|interpro:IPR033199|rcsb pdb:2JAI|rcsb pdb:2JAJ|rcsb pdb:3I2E|rcsb pdb:3I4A|rcsb pdb:3P8E|rcsb pdb:3P8P|rcsb pdb:6DGE|rcsb pdb:6SZP|rcsb pdb:6SZQ|rcsb pdb:7ULU|rcsb pdb:7ULV|rcsb pdb:7ULX|rcsb pdb:7USZ|rcsb pdb:7UT0|reactome:R-HSA-203615|dip:DIP-61582N|panther:PTHR12737(orthology-group)"	"interpro:IPR032859|interpro:IPR016484(GTP-binding, EngA)|interpro:IPR006073(GTP1/OBG)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR031166|go:""GO:0005525""(GTP binding)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0043022""(ribosome binding)|refseq:WP_002209813.1|refseq:YP_002347810.1|panther:PTHR43834(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/10	rogid:5h5LJE27Q8aAH2WUE1bMfUgZBvQ9606	rogid:a3YV0SOJTAdEtPWBkgeX/kJ6UR8632	intact-crc:53396BD546970702|rigid:W4l5bQjW+K3u+MMMaxdXQai4IGE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5FWG5	uniprotkb:Q8CKB2	intact:EBI-2859680	intact:EBI-2857486	psi-mi:q5fwg5_human(display_long)|uniprotkb:TLR1(gene name)|psi-mi:TLR1(display_short)	psi-mi:q8ckb2_yerpe(display_long)|uniprotkb:y3797(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859677|imex:IM-13779-6438	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR032675|interpro:IPR003591(Leucine-rich repeat, typical subtype)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0006954""(inflammatory response)|go:""GO:0016020""(membrane)|go:""GO:0045087""(innate immune response)|interpro:IPR035897|interpro:IPR017241(Toll-like receptor)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR052934|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zFgbJfku342P0xAecA2sE7ntJOY9606	rogid:5sqSFEOPSOBD89B6HPwdhZkqANc632	intact-crc:C5D73A937F25044B|rigid:2F1PoWE3yG/LzcWHO6bmTitaJ3Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5H9A3	uniprotkb:A0A3N4BA87	intact:EBI-2859666	intact:EBI-2849383|uniprotkb:Q74PH8|uniprotkb:A0A0H2W8Y4|uniprotkb:Q7CL39|uniprotkb:A0A384L9C4	psi-mi:q5h9a3_human(display_long)|uniprotkb:ATRX(gene name)|psi-mi:ATRX(display_short)|uniprotkb:ATP-dependent helicase ATRX(gene name synonym)|uniprotkb:X-linked nuclear protein(gene name synonym)|uniprotkb:RP5-875J14.1-004(orf name)	psi-mi:a0a3n4ba87_yerpe(display_long)|uniprotkb:ISU59_19965(orf name)|uniprotkb:YPO3618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859670|imex:IM-13779-6437	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR052131|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0006281""(DNA repair)|go:""GO:0016787""(hydrolase activity)"	"interpro:IPR004104(Oxidoreductase, C-terminal)|interpro:IPR000683(Oxidoreductase, N-terminal)|refseq:WP_002210025.1|go:""GO:0000166""(nucleotide binding)|go:""GO:0005829""(cytosol)|go:""GO:0017000""(antibiotic biosynthetic process)|go:""GO:0102497""(""scyllo-inositol dehydrogenase (NADP+) activity"")|interpro:IPR036291|refseq:YP_002348503.1|interpro:IPR051317|panther:PTHR43708(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zFSKJSnFDSaMjha4eoEvOMS9RpM9606	rogid:oAKjFkWV9yeIL0iPB/h3xOcZxZw632	intact-crc:E77115A814DDAF12|rigid:3XYXNwCW4LnlMONQw6b1SJnU6vs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CHW4	uniprotkb:Q5HYW2	intact:EBI-2848778|uniprotkb:Q74UT0	intact:EBI-2859639|uniprotkb:B2RN94|ensembl:ENSP00000488668.1|uniprotkb:A0A0J9YY34	psi-mi:purt_yerpe(display_long)|uniprotkb:purT(gene name)|psi-mi:purT(display_short)|uniprotkb:5'-phosphoribosylglycinamide transformylase 2(gene name synonym)|uniprotkb:Formate-dependent GAR transformylase(gene name synonym)|uniprotkb:GAR transformylase 2(gene name synonym)|uniprotkb:Non-folate glycinamide ribonucleotide transformylase(gene name synonym)|uniprotkb:Phosphoribosylglycinamide formyltransferase 2(gene name synonym)|uniprotkb:YPO1775(locus name)|uniprotkb:YP_1618(locus name)|uniprotkb:y2533(locus name)	psi-mi:nhsl2_human(display_long)|uniprotkb:NHSL2(gene name)|psi-mi:NHSL2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859636|imex:IM-13779-6440	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR003135(ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR005862(Phosphoribosylglycinamide formyltransferase 2)|interpro:IPR011054(Rudiment single hybrid motif)|refseq:WP_002211083.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004644""(phosphoribosylglycinamide formyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0043815""(phosphoribosylglycinamide formyltransferase 2 activity)|interpro:IPR048740|interpro:IPR054350|refseq:YP_002346772.1|panther:PTHR43055(orthology-group)"	"ensembl:ENSG00000204131.11(gene)|ensembl:ENST00000633930.2(transcript)|go:""GO:0030154""(cell differentiation)|interpro:IPR024845|refseq:NP_001013649.2|panther:PTHR23039(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bCau0DjK5zfXGn3uk1MMfw6Caso632	rogid:X46rSKPpXDENYdWFZmLU2rAFyI09606	intact-crc:3A99ECF38329F4C2|rigid:AxGM6bSnyAvtpKtEA3irjfU8NNI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B6K1	uniprotkb:Q5HYD9	intact:EBI-2841967|uniprotkb:Q7CHV2|uniprotkb:Q0WG31	intact:EBI-2802919	psi-mi:a0a3n4b6k1_yerpe(display_long)|uniprotkb:EIIAB-Man(gene name synonym)|uniprotkb:gptB(gene name)|psi-mi:gptB(display_short)|uniprotkb:EIII-Man(gene name synonym)|uniprotkb:manX(gene name synonym)|uniprotkb:ptsL(gene name synonym)|uniprotkb:YPO1758(locus name)	psi-mi:q5hyd9_human(display_long)|uniprotkb:DKFZp686M0619(gene name)|psi-mi:DKFZp686M0619(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859648|imex:IM-13779-6436	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004701(Phosphotransferase system, fructose subfamily IIA component)|interpro:IPR013789(Phosphotransferase system, fructose subfamily IIA component, subgroup)|interpro:IPR004720(Phosphotransferase system, sorbose subfamily IIB component)|interpro:IPR018455|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|interpro:IPR033887|interpro:IPR036662|interpro:IPR036667|refseq:WP_002211069.1|refseq:YP_002346757.1|interpro:IPR051471|panther:PTHR33799(orthology-group)"	"interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|go:""GO:0020037""(heme binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR036400|interpro:IPR050668"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6EMnus36OolbaozHpfdN+4jAtF0632	rogid:EFTwE3PrtKQyWkuDfO7Zsfy3iog9606	intact-crc:9BCC2B0CF5E2C345|rigid:+J2uQ9JdMWh6Oyw3EgHQDuWnui4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3S9	uniprotkb:Q8D0T1	intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929.6|ensembl:ENSP00000508809.1|ensembl:ENSP00000510366.1|ensembl:ENSP00000510377.1	intact:EBI-2846795|uniprotkb:Q74T24	psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym)	psi-mi:q8d0t1_yerpe(display_long)|uniprotkb:aat2(gene name)|psi-mi:aat2(display_short)|uniprotkb:YP_2369(locus name)|uniprotkb:y1628(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859699|imex:IM-13779-6443	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_982283.2|ensembl:ENSG00000264343.7(gene)|ensembl:ENST00000362074.8(transcript)|ensembl:ENST00000686973.1(transcript)|ensembl:ENST00000687833.1(transcript)|ensembl:ENST00000692119.1(transcript)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030154""(cell differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|interpro:IPR049883|interpro:IPR050906|mint:Q7Z3S9|reactome:R-HSA-2979096|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1"	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR051926"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606	rogid:7IrpMzFq+fCJGRerouk+rCU3GV8632	intact-crc:D25A96F204562413|rigid:ubkb42IeVdO7Cc4C7yq29I4Nl8w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAF1	uniprotkb:Q59H65	intact:EBI-2847121|uniprotkb:Q0WAF4	intact:EBI-2798309	psi-mi:wzye_yerpe(display_long)|uniprotkb:wzyE(gene name)|psi-mi:wzyE(display_short)|uniprotkb:wecF(gene name synonym)|uniprotkb:YPO3856(locus name)|uniprotkb:y0372(locus name)|uniprotkb:YP_3189(locus name)	psi-mi:q59h65_human(display_long)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859713|imex:IM-13779-6444	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010691(WzyE)|go:""GO:0005886""(plasma membrane)|go:""GO:0009246""(enterobacterial common antigen biosynthetic process)|refseq:WP_002211978.1|refseq:YP_002348734.1"	"go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006081""(aldehyde metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0016620""(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR012394(""Aldehyde dehydrogenase NAD(P)-dependent"")|interpro:IPR029510|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DunRXV3CpPUWSRQnNPV6bIM/Ao8632	rogid:l/Y9pGlqG7pZkd47kqTczjuKOpM9606	intact-crc:62FFE3C5FF5B27AA|rigid:8ZM4pfraDRBXPyetRSTDCKvYieg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q7Z3S9	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929.6|ensembl:ENSP00000508809.1|ensembl:ENSP00000510366.1|ensembl:ENSP00000510377.1	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859706|imex:IM-13779-6442	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:NP_982283.2|ensembl:ENSG00000264343.7(gene)|ensembl:ENST00000362074.8(transcript)|ensembl:ENST00000686973.1(transcript)|ensembl:ENST00000687833.1(transcript)|ensembl:ENST00000692119.1(transcript)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030154""(cell differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|interpro:IPR049883|interpro:IPR050906|mint:Q7Z3S9|reactome:R-HSA-2979096|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606	intact-crc:9CAF28BEDBEA0291|rigid:76dqNlyvt2kA4rf88+Bw6gr298k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q59GM9	uniprotkb:A0A2U2H442	intact:EBI-2859720	intact:EBI-2850550|uniprotkb:Q74WH5|uniprotkb:A0A5P8YDV2|uniprotkb:Q0WHG4|uniprotkb:Q7CHB4|uniprotkb:A0A384LD81	psi-mi:q59gm9_human(display_long)	psi-mi:a0a2u2h442_yerpe(display_long)|uniprotkb:YPO1245(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859723|imex:IM-13779-6441	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR035090|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|go:""GO:0005977""(glycogen metabolic process)|go:""GO:0008184""(glycogen phosphorylase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0031220""(maltodextrin phosphorylase activity)"	refseq:WP_002208853.1|refseq:YP_002346274.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MgsR36OW1gYmTWiJDu7dQ5gCCLE9606	rogid:BxXs1C2W2KnC7YYSP0bq8vjxXow632	intact-crc:F02E99C2E2FF73A2|rigid:1B6+FHGAq+rKdcaxElm4OyVUX44	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q59GM9	uniprotkb:Q8ZHI8	intact:EBI-2859720	intact:EBI-2853665|uniprotkb:Q0WID5	psi-mi:q59gm9_human(display_long)	"psi-mi:gcsp_yerpe(display_long)|uniprotkb:gcvP(gene name)|psi-mi:gcvP(display_short)|uniprotkb:Glycine cleavage system P-protein(gene name synonym)|uniprotkb:Glycine decarboxylase(gene name synonym)|uniprotkb:""Glycine dehydrogenase (aminomethyl-transferring)""(gene name synonym)|uniprotkb:YPO0905(locus name)|uniprotkb:YP_3602(locus name)|uniprotkb:y3292(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859730|imex:IM-13779-6449	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR035090|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|go:""GO:0005977""(glycogen metabolic process)|go:""GO:0008184""(glycogen phosphorylase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0031220""(maltodextrin phosphorylase activity)"	"refseq:WP_002209947.1|interpro:IPR020581|interpro:IPR003437(Glycine cleavage system P-protein)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:""GO:0004375""(""glycine dehydrogenase (decarboxylating) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0016594""(glycine binding)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR049315|interpro:IPR049316|refseq:YP_002345953.1|panther:PTHR11773(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MgsR36OW1gYmTWiJDu7dQ5gCCLE9606	rogid:DyITTFcMLNG19IvzD1ZE6K5EW/U632	intact-crc:872995FB770B8223|rigid:L+0b2kWj0OttijcM+ANv7q8nF5I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q59EG5	uniprotkb:Q8ZH40	intact:EBI-2859747	intact:EBI-2853216|uniprotkb:Q0WHX3	psi-mi:q59eg5_human(display_long)	psi-mi:metq_yerpe(display_long)|uniprotkb:metQ(gene name)|psi-mi:metQ(display_short)|uniprotkb:YPO1071(locus name)|uniprotkb:y3106(locus name)|uniprotkb:YP_2778(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859744|imex:IM-13779-6448	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR050887|interpro:IPR013783(Immunoglobulin-like fold)|go:""GO:0004567""(beta-mannosidase activity)|interpro:IPR036156|interpro:IPR041447|interpro:IPR041625"	"interpro:IPR004872(NLPA lipoprotein)|refseq:WP_002212159.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|refseq:YP_002346115.1|panther:PTHR30429(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:U3Qf1BD9mnUngVXy6fPLB67d7QY9606	rogid:Q6fJ70CWCE/DbbUHlJ9Z7HHzEig632	intact-crc:A0ACEBAA4541A3A1|rigid:ytcWwXnGB6hv4bUSw+TCaLwDcOg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W834	uniprotkb:Q59F13	intact:EBI-2846024	intact:EBI-2826244	psi-mi:a0a0h2w834_yerpe(display_long)|uniprotkb:YP_3851(locus name)|uniprotkb:y0170(locus name)	psi-mi:q59f13_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859737|imex:IM-13779-6445	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A6B3T3V9(uniprot-removed-ac)|refseq:WP_011055205.1	"interpro:IPR032466|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006331(Adenosine deaminase-related growth factor)|go:""GO:0004000""(adenosine deaminase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0006154""(adenosine catabolic process)|interpro:IPR006330(Adenosine deaminase)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:saqLPnEWmzpLG+E2JzO8S+w+WY8632	rogid:uvRTS0e0OpK7Zx2tnXKrGYlbCXY9606	intact-crc:DD4AB2C48C8E7D9E|rigid:IMWAiWr1RhQq6x325a+4KlcgbQQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A384KHP8	uniprotkb:Q59E90	intact:EBI-2840740|uniprotkb:Q74S58|uniprotkb:Q0WHX7|uniprotkb:Q7CH24	intact:EBI-2859764	psi-mi:a0a384khp8_yerpe(display_long)|uniprotkb:cutF(gene name)|psi-mi:cutF(display_short)|uniprotkb:nlpE(gene name synonym)|uniprotkb:YPO1067(locus name)	psi-mi:q59e90_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859768|imex:IM-13779-6447	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR007298(Copper resistance lipoprotein NlpE)|interpro:IPR033450|interpro:IPR038139|interpro:IPR043176|refseq:YP_002346111.1	"interpro:IPR027291|interpro:IPR028995|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR011682(Glycosyl hydrolases 38, C-terminal)|interpro:IPR015341(Glycoside hydrolase, family 38, central region)|interpro:IPR000602(Glycoside hydrolase, family 38, core)|interpro:IPR041147|interpro:IPR050843|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|go:""GO:0004559""(alpha-mannosidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0006013""(mannose metabolic process)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR037094|interpro:IPR048534"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ryLPtdXQoNwxiqxUzYaySoAkJkc632	rogid:u0xXtJ1XNIhgpgsif8M8O4OhKjE9606	intact-crc:58833688410D2E8F|rigid:bTwq/mEyornWfT8oX8mSo4M+mfU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W5B3	uniprotkb:Q59E94	intact:EBI-2852094|uniprotkb:Q74US2|uniprotkb:A0A3N4BGG1|uniprotkb:Q0WG25|uniprotkb:Q7CHV7|uniprotkb:A0A384LL75	intact:EBI-2859757	psi-mi:a0a0h2w5b3_yerpe(display_long)|uniprotkb:hpaH(gene name)|psi-mi:hpaH(display_short)|uniprotkb:hpcG(gene name synonym)|uniprotkb:YPO1766(locus name)	psi-mi:q59e94_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859754|imex:IM-13779-6446	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012690(2-oxo-hepta-3-ene-1,7-dioic acid hydratase)|refseq:WP_002211074.1|go:""GO:0009056""(catabolic process)|go:""GO:0018817""(2-oxo-hept-3-ene-1,7-dioate hydratase activity)|interpro:IPR036663|refseq:YP_002346763.1|interpro:IPR050772|interpro:IPR011234(Fumarylacetoacetase, C-terminal-related)"	"interpro:IPR029045|interpro:IPR022408|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR001753(Crotonase, core)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR051053|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0004165""(""delta(3)-delta(2)-enoyl-CoA isomerase activity"")|go:""GO:0005777""(peroxisome)|interpro:IPR035984"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:51nRlHF8JkFhYaUo6oPpqkEY8Ug632	rogid:wBDPJjLi4dGI4vHn8Dm9Avrh6Nk9606	intact-crc:AF235F20674E57DF|rigid:kU/mIGZ1Bc06i6gRqtwq+ADHxv4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q584P1	uniprotkb:P17778	intact:EBI-2802940	intact:EBI-2842665|uniprotkb:O68701	psi-mi:q584p1_human(display_long)|uniprotkb:PCYOX1(gene name)|psi-mi:PCYOX1(display_short)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859786|imex:IM-13779-6450	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010795(Prenylcysteine lyase)|go:""GO:0001735""(prenylcysteine oxidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0030328""(prenylcysteine catabolic process)|interpro:IPR017046(Prenylcysteine oxidase)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bjvqPvzL434WpgPB38ERK9k2KKk9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:E25C38E00B957336|rigid:PFi2Ublxr/ie1GMspSh7Ozrov/w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NP72	uniprotkb:A0A3N4BNK4	intact:EBI-722247|uniprotkb:Q53FX8|uniprotkb:Q6FIH1|uniprotkb:B3KMC7|uniprotkb:D3DRW1|intact:EBI-2859793|uniprotkb:Q56UN9|uniprotkb:B7Z333|ensembl:ENSP00000349415.7|ensembl:ENSP00000507542.1	intact:EBI-2855448|uniprotkb:A0A380PK27|uniprotkb:Q0WDQ1|uniprotkb:Q7CJU1	psi-mi:rab18_human(display_long)|uniprotkb:RAB18(gene name)|psi-mi:RAB18(display_short)	psi-mi:a0a3n4bnk4_yerpe(display_long)|uniprotkb:ybfM(gene name)|psi-mi:ybfM(display_short)|uniprotkb:YPO2631(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859797|imex:IM-13779-6452	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2510""|ensembl:ENSG00000099246.19(gene)|ensembl:ENST00000356940.11(transcript)|ensembl:ENST00000682082.1(transcript)|go:""GO:0001654""(eye development)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0007420""(brain development)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019003""(GDP binding)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0034389""(lipid droplet organization)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR025662|interpro:IPR027417|interpro:IPR050227|mint:Q9NP72|rcsb pdb:1X3S|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-8873719|reactome:R-HSA-8876198|refseq:NP_001243339.1|refseq:NP_001243340.1|refseq:NP_001243341.1|refseq:NP_001243344.1|refseq:NP_067075.1|dip:DIP-60514N|panther:PTHR24073(orthology-group)"	"interpro:IPR005318(Outer membrane porin, bacterial)|refseq:WP_002210355.1|go:""GO:0016020""(membrane)|interpro:IPR023614|refseq:YP_002347587.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xw6DaP3FsJo34UZC/jqjJEWfSeg9606	rogid:kQOm62Hk7MNtNLAcnBC4bzThrBs632	intact-crc:7A2B2085B4D69B24|rigid:GwyEpS9l3DpTUSdEyvK7XE4vDB4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YB62	uniprotkb:Q58F08	intact:EBI-2844412|uniprotkb:Q74RA2|uniprotkb:Q0WAD3|uniprotkb:Q7CKZ7|uniprotkb:A0A0H2W7C0|uniprotkb:A0A384KQ85	intact:EBI-2859775	psi-mi:a0a5p8yb62_yerpe(display_long)|uniprotkb:YPO3879(locus name)	psi-mi:q58f08_human(display_long)|uniprotkb:ANKIB1(gene name)|psi-mi:ANKIB1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859779|imex:IM-13779-6451	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR018030|interpro:IPR025885|interpro:IPR025949|interpro:IPR043142|refseq:WP_002211999.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR042186|interpro:IPR037224|refseq:YP_002348755.1"	"interpro:IPR031127|interpro:IPR044066|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR047564|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|interpro:IPR045840"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LoLtCTl+KcIEJlQnZYPeOB8LOg4632	rogid:ExTT8S0NLtMXZSUe9AGaNAB/0sE9606	intact-crc:CD8B499B66E7DC89|rigid:xj9FDg933aKXTsu35qyYuP4bHbU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NP72	uniprotkb:P58497	intact:EBI-722247|uniprotkb:Q53FX8|uniprotkb:Q6FIH1|uniprotkb:B3KMC7|uniprotkb:D3DRW1|intact:EBI-2859793|uniprotkb:Q56UN9|uniprotkb:B7Z333|ensembl:ENSP00000349415.7|ensembl:ENSP00000507542.1	intact:EBI-2840431|uniprotkb:Q0WHQ6	psi-mi:rab18_human(display_long)|uniprotkb:RAB18(gene name)|psi-mi:RAB18(display_short)	psi-mi:mode_yerpe(display_long)|uniprotkb:modE(gene name)|psi-mi:modE(display_short)|uniprotkb:YPO1143(locus name)|uniprotkb:y3040(locus name)|uniprotkb:YP_1017(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859804|imex:IM-13779-6453	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2510""|ensembl:ENSG00000099246.19(gene)|ensembl:ENST00000356940.11(transcript)|ensembl:ENST00000682082.1(transcript)|go:""GO:0001654""(eye development)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0007420""(brain development)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019003""(GDP binding)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0034389""(lipid droplet organization)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR025662|interpro:IPR027417|interpro:IPR050227|mint:Q9NP72|rcsb pdb:1X3S|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-8873719|reactome:R-HSA-8876198|refseq:NP_001243339.1|refseq:NP_001243340.1|refseq:NP_001243341.1|refseq:NP_001243344.1|refseq:NP_067075.1|dip:DIP-60514N|panther:PTHR24073(orthology-group)"	"interpro:IPR005116(Transport-associated OB, type 1)|interpro:IPR004606(Molybdenum-pterin binding)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR003725(Molybdenum-binding protein, N-terminal)|interpro:IPR016462(Molybdate-dependent transcriptional regulator, ModE)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0015689""(molybdate ion transport)|go:""GO:0030151""(molybdenum ion binding)|refseq:WP_002210754.1|refseq:YP_002346182.1|interpro:IPR036388|interpro:IPR036390|interpro:IPR051815|panther:PTHR30432(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xw6DaP3FsJo34UZC/jqjJEWfSeg9606	rogid:UOXc5L3bZSzLOIuq9x/17/AMHmM632	intact-crc:F93711FE07F3A413|rigid:YVDgFfYGhaS9RxxXzkpw1EjrjPQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q53TK7	uniprotkb:Q8ZBC2	intact:EBI-2859847	intact:EBI-2851492|uniprotkb:Q0WBF3	psi-mi:q53tk7_human(display_long)|uniprotkb:ACYP2(gene name)|psi-mi:ACYP2(display_short)	psi-mi:if2_yerpe(display_long)|uniprotkb:infB(gene name)|psi-mi:infB(display_short)|uniprotkb:YPO3496(locus name)|uniprotkb:y0688(locus name)|uniprotkb:YP_0587(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859851|imex:IM-13779-6457	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020456|interpro:IPR001792(Acylphosphatase)|interpro:IPR017968|go:""GO:0003998""(acylphosphatase activity)|interpro:IPR036046"	"refseq:WP_002223151.1|interpro:IPR044145|interpro:IPR009061(Putative DNA binding)|interpro:IPR013575(Initiation factor 2 associated region, bacterial)|interpro:IPR006847(Translation initiation factor IF-2, N-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000178(Initiation factor 2)|interpro:IPR023115|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR015760(Translation initiation factor 2 related)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR036925|interpro:IPR053905|refseq:YP_002348385.1|panther:PTHR43381(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dEsmQZlWvXMF34wwzDiiMzLJuNQ9606	rogid:8Lhp4NihTUjn3nGZLA2K6kHbXg8632	intact-crc:AE75D9B7AA02E67E|rigid:7+r6jemnOghIixc/32uJmF0Jvjc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZD2	uniprotkb:Q8CL89	intact:EBI-2859814|uniprotkb:Q96J68|uniprotkb:Q53Z13|ensembl:ENSP00000315263.3	intact:EBI-2839866	psi-mi:gltp_human(display_long)|uniprotkb:GLTP(gene name)|psi-mi:GLTP(display_short)	psi-mi:q8cl89_yerpe(display_long)|uniprotkb:y1833(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859811|imex:IM-13779-6456	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057517.1|ensembl:ENSG00000139433.11(gene)|ensembl:ENST00000318348.9(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0008289""(lipid binding)|go:""GO:0017089""(glycolipid transfer activity)|go:""GO:0035627""(ceramide transport)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0042802""(identical protein binding)|go:""GO:0051861""(glycolipid binding)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:0120013""(lipid transfer activity)|go:""GO:1902387""(ceramide 1-phosphate binding)|go:""GO:1902388""(ceramide 1-phosphate transfer activity)|interpro:IPR014830(Glycolipid transfer protein, GLTP)|interpro:IPR036497|rcsb pdb:1SWX|rcsb pdb:1SX6|rcsb pdb:2EUK|rcsb pdb:2EUM|rcsb pdb:2EVD|rcsb pdb:2EVL|rcsb pdb:2EVS|rcsb pdb:2EVT|rcsb pdb:3RIC|rcsb pdb:3RWV|rcsb pdb:3RZN|rcsb pdb:3S0I|rcsb pdb:3S0K|rcsb pdb:4GH0|rcsb pdb:4GHP|rcsb pdb:4GHS|rcsb pdb:4GIX|rcsb pdb:4GJQ|rcsb pdb:4GVT|rcsb pdb:4GXD|rcsb pdb:4GXG|rcsb pdb:4H2Z|reactome:R-HSA-9845576|dip:DIP-59418N|panther:PTHR10219(orthology-group)"	interpro:IPR051551	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/22	rogid:LUCzH3RfKDyE95M1W2K3kTdI8Ec9606	rogid:kFqNelFqfI7J+vafdsofmQ0p0zA632	intact-crc:DB438E53F0AFCE1A|rigid:U4DQTR87lVur5J268z3VAT/56fE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WGQ5	uniprotkb:Q53RD8	intact:EBI-2853517|uniprotkb:Q74VA6|uniprotkb:Q7CHR0	intact:EBI-2859861	psi-mi:q0wgq5_yerpe(display_long)|uniprotkb:YPO1517(locus name)	psi-mi:q53rd8_human(display_long)|uniprotkb:LOC84524(gene name)|psi-mi:LOC84524(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859858|imex:IM-13779-6455	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050555|interpro:IPR025997|interpro:IPR028082|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002346533.1|panther:PTHR30036(orthology-group)"	"interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054361|go:""GO:0003723""(RNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR036855|interpro:IPR045124"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qnuiW6B7FZ3gckfa7i2/HzKZAI8632	rogid:F6VFwDwEECWpaphyv6kFPs383Fk9606	intact-crc:253991FFD2A2B199|rigid:pypacZ//Xd76f+1xYoccE0Fh/QE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q53TP4	uniprotkb:A0A2U2GXI1	intact:EBI-2859827	intact:EBI-2853305	psi-mi:q53tp4_human(display_long)|uniprotkb:MDA5(gene name)|psi-mi:MDA5(display_short)	psi-mi:a0a2u2gxi1_yerpe(display_long)|uniprotkb:flgL(gene name)|psi-mi:flgL(display_short)|uniprotkb:YP_1584(locus name)|uniprotkb:y2499(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859824|imex:IM-13779-6458	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR051363|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016787""(hydrolase activity)|go:""GO:0051607""(defense response to virus)|interpro:IPR038557|interpro:IPR041204"	"go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009424""(bacterial-type flagellum hook)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|uniprotkb:A0A5P8YE87(uniprot-removed-ac)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR013384(Flagellar hook-associated protein 3)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6PopBlBqUNNVpyHg5wBe8ptfucg9606	rogid:k1gRMllt847rh0+ibgAih55Crz0632	intact-crc:0A0E2670ABA730B9|rigid:vWkQK2iSk4WPYOAkcDHXXK0Mocg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q53TP4	uniprotkb:Q8CZW0	intact:EBI-2859827	intact:EBI-2859838|uniprotkb:Q74Q83	psi-mi:q53tp4_human(display_long)|uniprotkb:MDA5(gene name)|psi-mi:MDA5(display_short)	psi-mi:q8czw0_yerpe(display_long)|uniprotkb:serA(gene name)|psi-mi:serA(display_short)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:y3301(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859835|imex:IM-13779-6454	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR051363|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016787""(hydrolase activity)|go:""GO:0051607""(defense response to virus)|interpro:IPR038557|interpro:IPR041204"	"interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR050223|interpro:IPR029752|interpro:IPR029753|go:""GO:0004617""(phosphoglycerate dehydrogenase activity)|go:""GO:0051287""(NAD binding)|interpro:IPR054480|interpro:IPR036291|interpro:IPR045865"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6PopBlBqUNNVpyHg5wBe8ptfucg9606	rogid:NPmrxWZ3Tsy1t5cHRu3+OpWW/4I632	intact-crc:1C4687DD9CAFA30A|rigid:D2SQVdgM9hYnRZEBGvdGx72QgCA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIQ3	uniprotkb:Q53G34	intact:EBI-2842473|uniprotkb:Q8CZN8|uniprotkb:Q0WJM5	intact:EBI-2859880	psi-mi:deob_yerpe(display_long)|uniprotkb:deoB(gene name)|psi-mi:deoB(display_short)|uniprotkb:Phosphodeoxyribomutase(gene name synonym)|uniprotkb:YPO0439(locus name)|uniprotkb:y3741(locus name)|uniprotkb:YP_3743(locus name)	psi-mi:q53g34_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859890|imex:IM-13779-6459	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR010045(Phosphopentomutase)|interpro:IPR006124(Metalloenzyme)|interpro:IPR024052|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006015""(5-phosphoribose 1-diphosphate biosynthetic process)|go:""GO:0006018""(2-deoxyribose 1-phosphate catabolic process)|go:""GO:0008973""(phosphopentomutase activity)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0043094""(metabolic compound salvage)|refseq:WP_002209216.1|refseq:YP_002345513.1|panther:PTHR21110(orthology-group)"	"interpro:IPR018108|interpro:IPR023395|go:""GO:0005741""(mitochondrial outer membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LC8q64MdN91Wk2zrqc1En6sw9gU632	rogid:Otc5oNsm31STSrkimRWduBqBt9Q9606	intact-crc:38EBB607FC0EFDB7|rigid:Awuz6/JdfVMiyAXGqCOPJis5tEs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W6W4	uniprotkb:Q53R16	intact:EBI-2843643|uniprotkb:Q74RL4|uniprotkb:Q0WIX4|uniprotkb:Q7CGJ6|uniprotkb:A0A5P8YJ93|uniprotkb:A0A384LJE2	intact:EBI-2859869	psi-mi:a0a0h2w6w4_yerpe(display_long)|uniprotkb:YPO0700(locus name)	psi-mi:q53r16_human(display_long)|uniprotkb:KIAA0053(gene name)|psi-mi:KIAA0053(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859873|imex:IM-13779-6461	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008966(Adhesion, bacterial)|interpro:IPR000259(Fimbrial protein)|refseq:WP_002211456.1|go:""GO:0007155""(cell adhesion)|go:""GO:0009289""(pilus)|interpro:IPR036937|refseq:YP_002345764.1|interpro:IPR050263"	"interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR051025|go:""GO:0005096""(GTPase activator activity)|go:""GO:0007165""(signal transduction)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Q8Cvuk8bSe5Of8+4jTNlsIg6fbw632	rogid:VYnMaq7Q99HTAdTB9n2SSafLTcU9606	intact-crc:43432D49B777DBA5|rigid:EGMZuyD9dX7yTZ9lf1aASBJ9U7U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W3U3	uniprotkb:Q4VC00	intact:EBI-2859897|uniprotkb:Q74VW2|uniprotkb:A0A384LJQ9|uniprotkb:Q0WD94|uniprotkb:Q7CJX6|uniprotkb:A0A3N4B2U6	intact:EBI-2826326	psi-mi:a0a0h2w3u3_yerpe(display_long)|uniprotkb:bglB(gene name)|psi-mi:bglB(display_short)|uniprotkb:YPO2803(locus name)	psi-mi:q4vc00_human(display_long)|uniprotkb:MAN2B2(gene name)|psi-mi:MAN2B2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859902|imex:IM-13779-6462	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002347744.1|interpro:IPR002772(Glycoside hydrolase, family 3, C-terminal)|interpro:IPR001764(Glycoside hydrolase, family 3, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR019800|interpro:IPR026891|interpro:IPR050288|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_002209758.1|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR036881|interpro:IPR036962"	"interpro:IPR027291|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR011682(Glycosyl hydrolases 38, C-terminal)|interpro:IPR015341(Glycoside hydrolase, family 38, central region)|interpro:IPR000602(Glycoside hydrolase, family 38, core)|interpro:IPR028995|go:""GO:0004559""(alpha-mannosidase activity)|go:""GO:0006013""(mannose metabolic process)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR037094|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR050843"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CFSXDKLhXQPL2V/gU2biHJW5N3o632	rogid:7ezy7n98U8ZipQxJ3W8GKdldqNU9606	intact-crc:86E63D5F1B0A30E7|rigid:sfxfjd5/kH6lnf1cPkDfwCqrU+I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q53G34	uniprotkb:Q8ZFB2	intact:EBI-2859880	intact:EBI-2842002|uniprotkb:Q0WFY8|uniprotkb:Q8CWH3|uniprotkb:Q74UV7	psi-mi:q53g34_human(display_long)	psi-mi:flgh2_yerpe(display_long)|uniprotkb:flgH2(gene name)|psi-mi:flgH2(display_short)|uniprotkb:Basal body L-ring protein 2(gene name synonym)|uniprotkb:YPO1805(locus name)|uniprotkb:y2504(locus name)|uniprotkb:YP_1588(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859883|imex:IM-13779-6460	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018108|interpro:IPR023395|go:""GO:0005741""(mitochondrial outer membrane)"	"interpro:IPR000527(Flagellar L-ring protein)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009427""(bacterial-type flagellum basal body, distal rod, L ring)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:WP_002211116.1|refseq:YP_002346800.1|panther:PTHR34933(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Otc5oNsm31STSrkimRWduBqBt9Q9606	rogid:K+hG2Y1XkdBPEZly69izKbuTRvo632	intact-crc:6D916907FC572B49|rigid:Y8H/5djJ1NagLTfTPzOrlmZ2obU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P68587	uniprotkb:Q30154	intact:EBI-2844901|uniprotkb:P40295	intact:EBI-2798348|ensembl:ENSP00000364114.3|uniprotkb:Q29788|uniprotkb:C7C4X3|uniprotkb:O00283|uniprotkb:O46700|uniprotkb:Q29787|uniprotkb:B2RBV6|uniprotkb:Q30126|uniprotkb:O00157|uniprotkb:Q29703|uniprotkb:Q9MY54|uniprotkb:Q7M2H9|uniprotkb:Q30150|uniprotkb:Q8HWS7|uniprotkb:Q6SJR2|uniprotkb:Q8WLR5|uniprotkb:Q9XRX6|uniprotkb:Q30199	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	psi-mi:drb5_human(display_long)|uniprotkb:DR beta-5(gene name synonym)|uniprotkb:DR2-beta-2(gene name synonym)|uniprotkb:Dw2(gene name synonym)|uniprotkb:MHC class II antigen DRB5(gene name synonym)|uniprotkb:HLA-DRB5(gene name)|psi-mi:HLA-DRB5(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859954|imex:IM-13779-6466	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"ensembl:ENSG00000198502.7(gene)|ensembl:ENST00000374975.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:Q30154|rcsb pdb:1FV1|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1ZGL|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_002116.2|panther:PTHR19944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	rogid:ipwOu43xHvM4TpqIDU/kbn8ZJbI9606	intact-crc:D57B6FB9BB5BAE18|rigid:vihku5oDpnOH6wEiCevQGX1EE3s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZH30	uniprotkb:Q3MIB5	intact:EBI-2859927|uniprotkb:Q0WHW3	intact:EBI-2859932	psi-mi:rnh_yerpe(display_long)|uniprotkb:rnhA(gene name)|psi-mi:rnhA(display_short)|uniprotkb:YPO1081(locus name)|uniprotkb:y3095(locus name)|uniprotkb:YP_2768(locus name)	psi-mi:q3mib5_human(display_long)|uniprotkb:INMT(gene name)|psi-mi:INMT(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859936|imex:IM-13779-6465	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002346125.1|interpro:IPR022892|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002156(Ribonuclease H)|interpro:IPR050092|refseq:WP_002210699.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0004523""(RNA-DNA hybrid ribonuclease activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0043137""(DNA replication, removal of RNA primer)|interpro:IPR036397|panther:PTHR10642(orthology-group)"	"interpro:IPR025820|interpro:IPR000940(Methyltransferase, NNMT/PNMT/TEMT)|interpro:IPR029063|interpro:IPR053384|go:""GO:0008757""(S-adenosylmethionine-dependent methyltransferase activity)|go:""GO:0032259""(methylation)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2fW9scaTvqM3UD1STQFx9lltiBQ632	rogid:N+M/BUQyKbHZYaKU0O7v3A21GdE9606	intact-crc:4AA54676BECCD7F9|rigid:h/dgnASAqfTSSLXDUBoiRiPKXnc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P68587	uniprotkb:Q6ZSB9	intact:EBI-2844901|uniprotkb:P40295	intact:EBI-2859943|intact:EBI-3943814|uniprotkb:A8K936|uniprotkb:Q32ML0|uniprotkb:Q59FJ4|uniprotkb:Q5EBN0|uniprotkb:Q8TB80|ensembl:ENSP00000338807.4	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	psi-mi:zbt49_human(display_long)|uniprotkb:ZBTB49(gene name)|psi-mi:ZBTB49(display_short)|uniprotkb:ZNF509(gene name synonym)|uniprotkb:Zinc finger protein 509(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859947|imex:IM-13779-6467	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"refseq:XP_011511718.1|refseq:NP_660334.3|refseq:XP_005248008.1|refseq:NP_001317554.1|ensembl:ENSG00000168826.16(gene)|ensembl:ENST00000337872.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050457|panther:PTHR24399(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	rogid:KdzgnOiwQcwvEM7Z34SXOgYi5y49606	intact-crc:55AA81D8039CD807|rigid:0fJ/7V6sTVUiylPXmOJKd4bcOk4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P58582	uniprotkb:Q4VAK3	intact:EBI-2846820|uniprotkb:Q0WIA6	intact:EBI-2803046	psi-mi:gshb_yerpe(display_long)|uniprotkb:gshB(gene name)|psi-mi:gshB(display_short)|uniprotkb:GSH synthetase(gene name synonym)|uniprotkb:Glutathione synthase(gene name synonym)|uniprotkb:YPO0935(locus name)|uniprotkb:y3321(locus name)|uniprotkb:YP_3507(locus name)	psi-mi:q4vak3_human(display_long)|uniprotkb:OFD1(gene name)|psi-mi:OFD1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859909|imex:IM-13779-6464	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR006284(Glutathione synthetase, prokaryotic)|interpro:IPR004218(Prokaryotic glutathione synthetase, ATP-binding)|interpro:IPR004215(Prokaryotic glutathione synthetase, N-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|refseq:WP_002209976.1|go:""GO:0004363""(glutathione synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|refseq:YP_002345982.1|panther:PTHR21621(orthology-group)"	interpro:IPR055289	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2PCcRO+ezg1vmWad2fXePKESKh4632	rogid:89UeJ/4mu1bIHqVh+2BOq1G1SoM9606	intact-crc:AA1D46F057A0F7BE|rigid:CvLiSnBXzOGVe7LAh13059O4Eng	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q49A13	uniprotkb:P68587	intact:EBI-2859919	intact:EBI-2844901|uniprotkb:P40295	psi-mi:q49a13_human(display_long)|uniprotkb:ZNF800(gene name)|psi-mi:ZNF800(display_short)	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859916|imex:IM-13779-6463	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039149	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5EqGJ0N+wWzWDVa+Ll7BIB02NOM9606	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	intact-crc:26CEB3D3B896685F|rigid:g6/xKXkzYKnEcM+8t3WaQBIIFkM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B631	uniprotkb:Q30154	intact:EBI-2859968|uniprotkb:Q74VK7|uniprotkb:Q0WHB8|uniprotkb:Q7CHE6	intact:EBI-2798348|ensembl:ENSP00000364114.3|uniprotkb:Q29788|uniprotkb:C7C4X3|uniprotkb:O00283|uniprotkb:O46700|uniprotkb:Q29787|uniprotkb:B2RBV6|uniprotkb:Q30126|uniprotkb:O00157|uniprotkb:Q29703|uniprotkb:Q9MY54|uniprotkb:Q7M2H9|uniprotkb:Q30150|uniprotkb:Q8HWS7|uniprotkb:Q6SJR2|uniprotkb:Q8WLR5|uniprotkb:Q9XRX6|uniprotkb:Q30199	psi-mi:a0a3n4b631_yerpe(display_long)|uniprotkb:YPO1294(locus name)	psi-mi:drb5_human(display_long)|uniprotkb:DR beta-5(gene name synonym)|uniprotkb:DR2-beta-2(gene name synonym)|uniprotkb:Dw2(gene name synonym)|uniprotkb:MHC class II antigen DRB5(gene name synonym)|uniprotkb:HLA-DRB5(gene name)|psi-mi:HLA-DRB5(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859973|imex:IM-13779-6472	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002346320.1|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR050107|refseq:WP_002208803.1|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|panther:PTHR43790(orthology-group)"	"ensembl:ENSG00000198502.7(gene)|ensembl:ENST00000374975.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:Q30154|rcsb pdb:1FV1|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1ZGL|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_002116.2|panther:PTHR19944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0VaVASVo0mvyDl5gKVp5uAy75QI632	rogid:ipwOu43xHvM4TpqIDU/kbn8ZJbI9606	intact-crc:6062EF4910773AB8|rigid:LImyLK1eG3/lG5+VKUGbCm8Owr0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H2S0	uniprotkb:P42892	intact:EBI-2845117|uniprotkb:Q74SK9|uniprotkb:Q0WCU8|uniprotkb:Q7CJE4|uniprotkb:A0A384LH60	intact:EBI-2859983|intact:EBI-2907408|uniprotkb:A8K3P1|uniprotkb:B4E291|uniprotkb:Q14217|uniprotkb:Q17RN5|uniprotkb:Q2Z2K8|uniprotkb:Q58GE7|uniprotkb:Q5THM5|uniprotkb:Q5THM7|uniprotkb:Q5THM8|uniprotkb:Q9UJQ6|uniprotkb:Q9UPF4|uniprotkb:Q9UPM4|uniprotkb:Q9Y501|ensembl:ENSP00000364028.6	psi-mi:a0a2u2h2s0_yerpe(display_long)|uniprotkb:dmsB(gene name)|psi-mi:dmsB(display_short)|uniprotkb:YPO2966(locus name)	psi-mi:ece1_human(display_long)|uniprotkb:ECE1(gene name)|psi-mi:ECE1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859980|imex:IM-13779-6469	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR014297(Dimethylsulphoxide reductase, chain B)|interpro:IPR017900|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002211603.1|refseq:YP_002347890.1|interpro:IPR050954|panther:PTHR43177(orthology-group)"	"ensembl:ENSG00000117298.16(gene)|ensembl:ENST00000374893.11(transcript)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007507""(heart development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0010814""(substance P catabolic process)|go:""GO:0010815""(bradykinin catabolic process)|go:""GO:0010816""(calcitonin catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016485""(protein processing)|go:""GO:0016486""(peptide hormone processing)|go:""GO:0017046""(peptide hormone binding)|go:""GO:0019229""(regulation of vasoconstriction)|go:""GO:0031982""(vesicle)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0034959""(endothelin maturation)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0042447""(hormone catabolic process)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043583""(ear development)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0060037""(pharyngeal system development)|go:""GO:0060385""(axonogenesis involved in innervation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097492""(sympathetic neuron axon guidance)|go:""GO:1902287""(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR000718(Peptidase M13, neprilysin)|interpro:IPR008753(Peptidase M13)|interpro:IPR018497|interpro:IPR024079|interpro:IPR042089|mint:P42892|rcsb pdb:3DWB|reactome:R-HSA-375276|refseq:NP_001106818.1|refseq:NP_001106819.1|refseq:NP_001106820.1|refseq:NP_001388.1|refseq:XP_006710461.1|refseq:XP_011539175.1|refseq:XP_016856000.1|efo:""Orphanet:388""|panther:PTHR11733(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9jyIOCO41ainU3jSCjdpHqWlt50632	rogid:Naxpnfs4LctZGDLImqijiMIKFvY9606	intact-crc:BF6EA71341C54FCD|rigid:lat9HbjSAzSWXgkTNomgFT73LQM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P42892	uniprotkb:A0A5P8YAL1	intact:EBI-2859983|intact:EBI-2907408|uniprotkb:A8K3P1|uniprotkb:B4E291|uniprotkb:Q14217|uniprotkb:Q17RN5|uniprotkb:Q2Z2K8|uniprotkb:Q58GE7|uniprotkb:Q5THM5|uniprotkb:Q5THM7|uniprotkb:Q5THM8|uniprotkb:Q9UJQ6|uniprotkb:Q9UPF4|uniprotkb:Q9UPM4|uniprotkb:Q9Y501|ensembl:ENSP00000364028.6	intact:EBI-2847693|uniprotkb:Q74QT5|uniprotkb:A0A0H2W741|uniprotkb:Q7CFS1|uniprotkb:A0A384LBQ5	psi-mi:ece1_human(display_long)|uniprotkb:ECE1(gene name)|psi-mi:ECE1(display_short)	psi-mi:a0a5p8yal1_yerpe(display_long)|uniprotkb:yhjW(gene name)|psi-mi:yhjW(display_short)|uniprotkb:YPO4013(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859991|imex:IM-13779-6471	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000117298.16(gene)|ensembl:ENST00000374893.11(transcript)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0003100""(regulation of systemic arterial blood pressure by endothelin)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007507""(heart development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0010814""(substance P catabolic process)|go:""GO:0010815""(bradykinin catabolic process)|go:""GO:0010816""(calcitonin catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016485""(protein processing)|go:""GO:0016486""(peptide hormone processing)|go:""GO:0017046""(peptide hormone binding)|go:""GO:0019229""(regulation of vasoconstriction)|go:""GO:0031982""(vesicle)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0034959""(endothelin maturation)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0042447""(hormone catabolic process)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043583""(ear development)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0060037""(pharyngeal system development)|go:""GO:0060385""(axonogenesis involved in innervation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097492""(sympathetic neuron axon guidance)|go:""GO:1902287""(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR000718(Peptidase M13, neprilysin)|interpro:IPR008753(Peptidase M13)|interpro:IPR018497|interpro:IPR024079|interpro:IPR042089|mint:P42892|rcsb pdb:3DWB|reactome:R-HSA-375276|refseq:NP_001106818.1|refseq:NP_001106819.1|refseq:NP_001106820.1|refseq:NP_001388.1|refseq:XP_006710461.1|refseq:XP_011539175.1|refseq:XP_016856000.1|efo:""Orphanet:388""|panther:PTHR11733(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR012549(Protein of unknown function DUF1705)|interpro:IPR000917(Sulphatase)|refseq:WP_002209571.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009244""(lipopolysaccharide core region biosynthetic process)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0043838""(""phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity"")|interpro:IPR040423|refseq:YP_002348879.1|panther:PTHR30443(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Naxpnfs4LctZGDLImqijiMIKFvY9606	rogid:HkeTpMUkl5+g00S4VZSWIDHQ28c632	intact-crc:78431E952B6BF9C8|rigid:akMjQRz41cxE+eqiw2UsBtULGPg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q30154	uniprotkb:Q8CLT0	intact:EBI-2798348|ensembl:ENSP00000364114.3|uniprotkb:Q29788|uniprotkb:C7C4X3|uniprotkb:O00283|uniprotkb:O46700|uniprotkb:Q29787|uniprotkb:B2RBV6|uniprotkb:Q30126|uniprotkb:O00157|uniprotkb:Q29703|uniprotkb:Q9MY54|uniprotkb:Q7M2H9|uniprotkb:Q30150|uniprotkb:Q8HWS7|uniprotkb:Q6SJR2|uniprotkb:Q8WLR5|uniprotkb:Q9XRX6|uniprotkb:Q30199	intact:EBI-2855052|uniprotkb:Q74PF1	psi-mi:drb5_human(display_long)|uniprotkb:DR beta-5(gene name synonym)|uniprotkb:DR2-beta-2(gene name synonym)|uniprotkb:Dw2(gene name synonym)|uniprotkb:MHC class II antigen DRB5(gene name synonym)|uniprotkb:HLA-DRB5(gene name)|psi-mi:HLA-DRB5(display_short)	psi-mi:q8clt0_yerpe(display_long)|uniprotkb:YP_3956(locus name)|uniprotkb:y0280(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2859961|imex:IM-13779-6468	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000198502.7(gene)|ensembl:ENST00000374975.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:Q30154|rcsb pdb:1FV1|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1ZGL|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_002116.2|panther:PTHR19944(orthology-group)"	interpro:IPR010732(Protein of unknown function DUF1305)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ipwOu43xHvM4TpqIDU/kbn8ZJbI9606	rogid:YJLIYYyJ4C5Tki3xmcQ2jFOW6ig632	intact-crc:44EBD906C9A8E9F5|rigid:Q3rV2nzvAJRtedxRC33nC3cmdoA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2859998	uniprotkb:A0A0H2W572	-	intact:EBI-2860005|uniprotkb:Q74TT6|uniprotkb:Q0WER6|uniprotkb:Q7CIK2|uniprotkb:A0A380PDA9	psi-mi:in4l2_human(display_short)|psi-mi:EBI-2859998(display_long)|uniprotkb:INTS4L2(gene name)|psi-mi:INTS4L2(display_short)	psi-mi:a0a0h2w572_yerpe(display_long)|uniprotkb:araF(gene name)|psi-mi:araF(display_short)|uniprotkb:YPO2255(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860002|imex:IM-13779-6470	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q2T9F4(uniprot-removed-ac)	"refseq:YP_002347222.1|interpro:IPR001761(Periplasmic binding protein/LacI transcriptional regulator)|interpro:IPR028082|refseq:WP_002210589.1|interpro:IPR026266|interpro:IPR050555|go:""GO:0042597""(periplasmic space)|go:""GO:0042882""(L-arabinose transmembrane transport)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Gv4S6+hlHR0zCf03ly4eqZcBTB49606	rogid:fzouHkH0BvQ3kltm5kIDtacOREY632	intact-crc:31D80A62A972A7B3|rigid:MShUjmUG7RtbAQEownTrWuc3aKw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CL88	uniprotkb:Q2NL98	intact:EBI-2857164	intact:EBI-2803134|uniprotkb:B3KW55|ensembl:ENSP00000343348.2|ensembl:ENSP00000517810.1	psi-mi:q8cl88_yerpe(display_long)|uniprotkb:y1834(locus name)	psi-mi:vmac_human(display_long)|uniprotkb:VMAC(gene name)|psi-mi:VMAC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860033|imex:IM-13779-6475	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR051551|go:""GO:0019867""(outer membrane)|interpro:IPR036709|interpro:IPR043990"	"refseq:NP_001017921.1|ensembl:ENSG00000187650.4(gene)|ensembl:ENSG00000292061.1(gene)|ensembl:ENST00000339485.4(transcript)|ensembl:ENST00000709632.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0045098""(type III intermediate filament)|mint:Q2NL98|panther:PTHR34707(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:G0mR8P5CZ016j1+vnvWb9h/RZDU632	rogid:uE3A2XhetBP92kP4nP8zhjNG0co9606	intact-crc:8EB60040C58474D8|rigid:Y74ciRmw+aNHDQhHB6JwEb6S6Jw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q2NL98	uniprotkb:P58492	intact:EBI-2803134|uniprotkb:B3KW55|ensembl:ENSP00000343348.2|ensembl:ENSP00000517810.1	intact:EBI-2843087|uniprotkb:Q0WCS4	psi-mi:vmac_human(display_long)|uniprotkb:VMAC(gene name)|psi-mi:VMAC(display_short)	psi-mi:zipa_yerpe(display_long)|uniprotkb:zipA(gene name)|psi-mi:zipA(display_short)|uniprotkb:YPO2990(locus name)|uniprotkb:y1491(locus name)|uniprotkb:YP_2615(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860014|imex:IM-13779-6474	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001017921.1|ensembl:ENSG00000187650.4(gene)|ensembl:ENSG00000292061.1(gene)|ensembl:ENST00000339485.4(transcript)|ensembl:ENST00000709632.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0045098""(type III intermediate filament)|mint:Q2NL98|panther:PTHR34707(orthology-group)"	"interpro:IPR011919(Cell division protein ZipA)|interpro:IPR007449(ZipA, C-terminal FtsZ-binding region)|go:""GO:0000917""(division septum assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|interpro:IPR036765|refseq:WP_002227089.1|refseq:YP_002347914.1|panther:PTHR38685(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uE3A2XhetBP92kP4nP8zhjNG0co9606	rogid:BeJdUMpcAUuTee/AiHsPfnL/+wg632	intact-crc:AD03B69827AB3D19|rigid:tyWdw1Mo8drbTQeG4pE91XMiM1Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CHW4	uniprotkb:Q2M2A3	intact:EBI-2848778|uniprotkb:Q74UT0	intact:EBI-2860040	psi-mi:purt_yerpe(display_long)|uniprotkb:purT(gene name)|psi-mi:purT(display_short)|uniprotkb:5'-phosphoribosylglycinamide transformylase 2(gene name synonym)|uniprotkb:Formate-dependent GAR transformylase(gene name synonym)|uniprotkb:GAR transformylase 2(gene name synonym)|uniprotkb:Non-folate glycinamide ribonucleotide transformylase(gene name synonym)|uniprotkb:Phosphoribosylglycinamide formyltransferase 2(gene name synonym)|uniprotkb:YPO1775(locus name)|uniprotkb:YP_1618(locus name)|uniprotkb:y2533(locus name)	psi-mi:q2m2a3_human(display_long)|uniprotkb:GANC(gene name)|psi-mi:GANC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860044|imex:IM-13779-6476	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR003135(ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR005862(Phosphoribosylglycinamide formyltransferase 2)|interpro:IPR011054(Rudiment single hybrid motif)|refseq:WP_002211083.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004644""(phosphoribosylglycinamide formyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0043815""(phosphoribosylglycinamide formyltransferase 2 activity)|interpro:IPR048740|interpro:IPR054350|refseq:YP_002346772.1|panther:PTHR43055(orthology-group)"	"interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR025887|interpro:IPR030458|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0090599""(alpha-glucosidase activity)|interpro:IPR048395"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bCau0DjK5zfXGn3uk1MMfw6Caso632	rogid:jx2exm9nBOyhbmx1PNfKEZQdt1M9606	intact-crc:B705B4060D1E989B|rigid:7vKozIO0KUaeVCZe0udwrznkMgw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q2NL98	uniprotkb:Q8D1N7	intact:EBI-2803134|uniprotkb:B3KW55|ensembl:ENSP00000343348.2|ensembl:ENSP00000517810.1	intact:EBI-2860024|uniprotkb:Q74PK4	psi-mi:vmac_human(display_long)|uniprotkb:VMAC(gene name)|psi-mi:VMAC(display_short)	psi-mi:q8d1n7_yerpe(display_long)|uniprotkb:pcp2(gene name synonym)|uniprotkb:YP_3901(locus name)|uniprotkb:y0221(locus name)|uniprotkb:slyB(gene name)|psi-mi:slyB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860021|imex:IM-13779-6473	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001017921.1|ensembl:ENSG00000187650.4(gene)|ensembl:ENSG00000292061.1(gene)|ensembl:ENST00000339485.4(transcript)|ensembl:ENST00000709632.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0045098""(type III intermediate filament)|mint:Q2NL98|panther:PTHR34707(orthology-group)"	"interpro:IPR008816(Rickettsia 17 kDa surface antigen)|interpro:IPR051407|go:""GO:0009279""(cell outer membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uE3A2XhetBP92kP4nP8zhjNG0co9606	rogid:GI4IQeYEDkq4EssGfpahsrs7LX8632	intact-crc:EC3A7F17C6E6586E|rigid:Vxoz22bzuj1H49C8VgkGN3jfMWM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CJM9	uniprotkb:O75132	intact:EBI-2860051|uniprotkb:Q74S81	intact:EBI-2860059|uniprotkb:B2RZH1|uniprotkb:Q9UGG8|uniprotkb:Q1ECU0|ensembl:ENSP00000216268.4	"psi-mi:rlmn_yerpe(display_long)|uniprotkb:rlmN(gene name)|psi-mi:rlmN(display_short)|uniprotkb:""23S rRNA (adenine(2503)-C(2))-methyltransferase""(gene name synonym)|uniprotkb:23S rRNA m2A2503 methyltransferase(gene name synonym)|uniprotkb:Ribosomal RNA large subunit methyltransferase N(gene name synonym)|uniprotkb:""tRNA (adenine(37)-C(2))-methyltransferase""(gene name synonym)|uniprotkb:tRNA m2A37 methyltransferase(gene name synonym)|uniprotkb:YPO2882(locus name)|uniprotkb:YP_2748(locus name)|uniprotkb:y1350(locus name)"	psi-mi:zbed4_human(display_long)|uniprotkb:ZBED4(gene name)|psi-mi:ZBED4(display_short)|uniprotkb:KIAA0637(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860056|imex:IM-13779-6478	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002347817.1|interpro:IPR004383(Conserved hypothetical protein CHP00048)|interpro:IPR007197(Radical SAM)|interpro:IPR040072|refseq:WP_002209820.1|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR027492|go:""GO:0000049""(tRNA binding)|go:""GO:0002935""(""tRNA (adenine(37)-C2)-methyltransferase activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0019843""(rRNA binding)|go:""GO:0030488""(tRNA methylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0070040""(""rRNA (adenine(2503)-C2-)-methyltransferase activity"")|go:""GO:0070475""(rRNA base methylation)|interpro:IPR048641|panther:PTHR30544(orthology-group)"	"refseq:NP_055653.2|ensembl:ENSG00000100426.8(gene)|ensembl:ENST00000216268.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0042802""(identical protein binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046983""(protein dimerization activity)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|interpro:IPR052035|mint:O75132|panther:PTHR46481(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kG8F68TmWQ35toLNiP51mzTTqgU632	rogid:T1pqiOcpLeOA25QudngK1xk+xaA9606	intact-crc:EA4DF3254EED40C5|rigid:YAfJ6AYIPRE4do4fstWIVlqesvc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A384KHP8	uniprotkb:Q15810	intact:EBI-2840740|uniprotkb:Q74S58|uniprotkb:Q0WHX7|uniprotkb:Q7CH24	intact:EBI-2803183	psi-mi:a0a384khp8_yerpe(display_long)|uniprotkb:cutF(gene name)|psi-mi:cutF(display_short)|uniprotkb:nlpE(gene name synonym)|uniprotkb:YPO1067(locus name)	psi-mi:q15810_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860108|imex:IM-13779-6481	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR007298(Copper resistance lipoprotein NlpE)|interpro:IPR033450|interpro:IPR038139|interpro:IPR043176|refseq:YP_002346111.1	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ryLPtdXQoNwxiqxUzYaySoAkJkc632	rogid:t8amiW2oum0jf0swQi36216VoJs9606	intact-crc:88F586B1850FD84F|rigid:S/E3Y9L/A0xeFI21rNUi60UxfwM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULD4	uniprotkb:A0A2U2H442	intact:EBI-1753470|uniprotkb:A6NJE2|uniprotkb:Q5R3K8|ensembl:ENSP00000350267.6|intact:EBI-2860074|uniprotkb:A6ND56|uniprotkb:B7ZLN5|uniprotkb:E7EX85|uniprotkb:Q17RB6	intact:EBI-2850550|uniprotkb:Q74WH5|uniprotkb:A0A5P8YDV2|uniprotkb:Q0WHG4|uniprotkb:Q7CHB4|uniprotkb:A0A384LD81	psi-mi:brpf3_human(display_long)|uniprotkb:BRPF3(gene name)|psi-mi:BRPF3(display_short)|uniprotkb:KIAA1286(gene name synonym)	psi-mi:a0a2u2h442_yerpe(display_long)|uniprotkb:YPO1245(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860071|imex:IM-13779-6480	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011512791.1|refseq:XP_005249067.1|refseq:XP_005249068.1|refseq:NP_056510.2|ensembl:ENSG00000096070.19(gene)|ensembl:ENST00000357641.10(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046872""(metal ion binding)|go:""GO:0050793""(regulation of developmental process)|go:""GO:0070776""(MOZ/MORF histone acetyltransferase complex)|go:""GO:1903706""(regulation of hemopoiesis)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR042005|interpro:IPR050701|mint:Q9ULD4|rcsb pdb:3PFS|reactome:R-HSA-114608|reactome:R-HSA-3214847|reactome:R-HSA-6804758|panther:PTHR13793(orthology-group)"	refseq:WP_002208853.1|refseq:YP_002346274.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CgyLb1z0upVoKfJxtzvybQ6NAkE9606	rogid:BxXs1C2W2KnC7YYSP0bq8vjxXow632	intact-crc:B3359CF45105E2EB|rigid:RnBP5fvFwp04HPZK/SiSPm0qSvg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NCM8	uniprotkb:Q7ARD3	intact:EBI-2512957|ensembl:ENSP00000364887.2|uniprotkb:Q7Z363|uniprotkb:O00432|uniprotkb:Q9HAE4|uniprotkb:Q8N977|uniprotkb:Q3C1U8|uniprotkb:Q6ZMX7|uniprotkb:Q16693|uniprotkb:Q6ZUM6|uniprotkb:Q4AC93|uniprotkb:Q92815|intact:EBI-2860086	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:dyhc2_human(display_long)|uniprotkb:DYNC2H1(gene name)|psi-mi:DYNC2H1(display_short)|uniprotkb:DYH1B(gene name synonym)|uniprotkb:KIAA1997(gene name synonym)|uniprotkb:Cytoplasmic dynein 2 heavy chain(gene name synonym)|uniprotkb:Dynein cytoplasmic heavy chain 2(gene name synonym)|uniprotkb:Dynein heavy chain isotype 1B(gene name synonym)|uniprotkb:Dynein heavy chain 11(gene name synonym)|uniprotkb:DHC1B(gene name synonym)|uniprotkb:DHC2(gene name synonym)|uniprotkb:DNCH2(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860083|imex:IM-13779-6477	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|ensembl:ENSG00000187240.17(gene)|ensembl:ENST00000375735.7(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005874""(microtubule)|go:""GO:0005930""(axoneme)|go:""GO:0007030""(Golgi organization)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0008569""(minus-end-directed microtubule motor activity)|go:""GO:0009953""(dorsal/ventral pattern formation)|go:""GO:0016485""(protein processing)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0021522""(spinal cord motor neuron differentiation)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0030900""(forebrain development)|go:""GO:0035721""(intraciliary retrograde transport)|go:""GO:0045177""(apical part of cell)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0045880""(positive regulation of smoothened signaling pathway)|go:""GO:0051959""(dynein light intermediate chain binding)|go:""GO:0060294""(cilium movement involved in cell motility)|go:""GO:0060976""(coronary vasculature development)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097542""(ciliary tip)|go:""GO:0097729""(9+2 motile cilium)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR026983|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR049400|interpro:IPR054354|mint:Q8NCM8|rcsb pdb:4RH7|rcsb pdb:8RGG|rcsb pdb:8RGH|reactome:R-HSA-5610787|reactome:R-HSA-5620924|refseq:NP_001073932.1|refseq:NP_001368.2|efo:""Orphanet:474""|efo:""Orphanet:93269""|efo:""Orphanet:93270""|efo:""Orphanet:93271""|panther:PTHR10676(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:c6bU2mT13JkjPNR9maL9+/R3IIg9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:5E968F5E92751851|rigid:wQS8+S7qbP4fj1u24QK7RNhgLP8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PFE9	uniprotkb:Q15810	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	intact:EBI-2803183	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	psi-mi:q15810_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860115|imex:IM-13779-6479	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	rogid:t8amiW2oum0jf0swQi36216VoJs9606	intact-crc:63B118146B7476B7|rigid:N8+sHWSMA24C5JjGDnmWcj9ll5U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5T4T6	uniprotkb:Q7CJD3	intact:EBI-2860160|uniprotkb:Q96EJ2|uniprotkb:Q6ZRM2|uniprotkb:A6NDS5|uniprotkb:Q08GK5|ensembl:ENSP00000283141.6|intact:EBI-28986132	intact:EBI-2855741|uniprotkb:Q74SM2|uniprotkb:A0A3N4AYV1|uniprotkb:A0A0H2W5Z0|uniprotkb:A0A5P8YHE2	psi-mi:syc2l_human(display_long)|uniprotkb:SYCP2L(gene name)|psi-mi:SYCP2L(display_short)|uniprotkb:C6orf177(gene name synonym)|uniprotkb:NO145(gene name synonym)|uniprotkb:145 kDa nucleolar protein homolog(gene name synonym)	psi-mi:q7cjd3_yerpe(display_long)|uniprotkb:YPO2950(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860157|imex:IM-13779-6484	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035364.2|ensembl:ENSG00000153157.14(gene)|ensembl:ENST00000283141.11(transcript)|go:""GO:0000779""(condensed chromosome, centromeric region)|go:""GO:0000800""(lateral element)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0051598""(meiotic recombination checkpoint signaling)|interpro:IPR024835|interpro:IPR040560|interpro:IPR041322|panther:PTHR15607(orthology-group)"	"interpro:IPR008966(Adhesion, bacterial)|interpro:IPR000259(Fimbrial protein)|refseq:WP_002215319.1|go:""GO:0007155""(cell adhesion)|go:""GO:0009289""(pilus)|interpro:IPR036937|refseq:YP_002347876.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4MbJgYu3T0cyMoBekHEj2YUOE0Y9606	rogid:6QQhHwv9NYl8rfpAQ7PgAyP2aUQ632	intact-crc:97A5455D07233C3E|rigid:1CQcFtZ7hrJ5z79YDSMQ6H2N6h8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZW4	uniprotkb:Q9HD43	intact:EBI-2851384|uniprotkb:Q74QA0	intact:EBI-1267176|uniprotkb:Q15426|uniprotkb:Q2NKN9|uniprotkb:Q2NKP0|intact:EBI-2826558|uniprotkb:C9JCH2|ensembl:ENSP00000365528.2	psi-mi:q8czw4_yerpe(display_long)|uniprotkb:y3277(locus name)|uniprotkb:fldB(gene name)|psi-mi:fldB(display_short)|uniprotkb:YP_3589(locus name)	psi-mi:ptprh_human(display_long)|uniprotkb:PTPRH(gene name)|psi-mi:PTPRH(display_short)|uniprotkb:SAP1(gene name synonym)|uniprotkb:Transmembrane-type protein-tyrosine phosphatase type H(gene name synonym)|uniprotkb:Stomach cancer-associated protein tyrosine phosphatase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860143|imex:IM-13779-6485	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029039|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001226(Flavodoxin, conserved site)|interpro:IPR010086(Flavodoxin, long chain)|go:""GO:0009055""(electron transfer activity)|go:""GO:0010181""(FMN binding)|interpro:IPR050619"	"ensembl:ENSG00000080031.10(gene)|ensembl:ENST00000376350.8(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031528""(microvillus membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR050713|mint:Q9HD43|rcsb pdb:7XC0|refseq:NP_001154912.2|refseq:NP_002833.4|panther:PTHR19134(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FZlCLDczSf2Gjm4UsIPSSoGJH6E632	rogid:a7NZuEFgvJhp4nMMr3+0yi9KT8Y9606	intact-crc:1C0BC98C030604BC|rigid:nXhyOSXTt7oZ8IV1YqghzWrRDfI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15810	uniprotkb:Q8ZAA1	intact:EBI-2803183	intact:EBI-2860122|uniprotkb:Q74RC5|uniprotkb:Q8D1L7|uniprotkb:Q0WAA3	psi-mi:q15810_human(display_long)	psi-mi:btub_yerpe(display_long)|uniprotkb:btuB(gene name)|psi-mi:btuB(display_short)|uniprotkb:Cobalamin receptor(gene name synonym)|uniprotkb:Outer membrane cobalamin translocator(gene name synonym)|uniprotkb:YPO3910(locus name)|uniprotkb:y0325(locus name)|uniprotkb:YP_3138(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860129|imex:IM-13779-6486	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010101(TonB-dependent vitamin B12 receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR039426|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0015420""(ABC-type vitamin B12 transporter activity)|go:""GO:0015889""(cobalamin transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0046930""(pore complex)|interpro:IPR036942|interpro:IPR037066|refseq:WP_002228170.1|panther:PTHR30069(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t8amiW2oum0jf0swQi36216VoJs9606	rogid:DOy5Ti+yMtG0ogW80Av35K2fKW0632	intact-crc:199458A08DC6C545|rigid:E1LIwv6LxdHK7tlzxbGifnsjlzo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HD43	uniprotkb:A0A3G5LD16	intact:EBI-1267176|uniprotkb:Q15426|uniprotkb:Q2NKN9|uniprotkb:Q2NKP0|intact:EBI-2826558|uniprotkb:C9JCH2|ensembl:ENSP00000365528.2	intact:EBI-2843158	psi-mi:ptprh_human(display_long)|uniprotkb:PTPRH(gene name)|psi-mi:PTPRH(display_short)|uniprotkb:SAP1(gene name synonym)|uniprotkb:Transmembrane-type protein-tyrosine phosphatase type H(gene name synonym)|uniprotkb:Stomach cancer-associated protein tyrosine phosphatase 1(gene name synonym)	psi-mi:a0a3g5ld16_yerpe(display_long)|uniprotkb:sufD(gene name)|psi-mi:sufD(display_short)|uniprotkb:NCTC5923_02768(orf name)|uniprotkb:YP_2188(locus name)|uniprotkb:y1937(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860136|imex:IM-13779-6482	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000080031.10(gene)|ensembl:ENST00000376350.8(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031528""(microvillus membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR050713|mint:Q9HD43|rcsb pdb:7XC0|refseq:NP_001154912.2|refseq:NP_002833.4|panther:PTHR19134(orthology-group)"	"uniprotkb:A0A6B3T3E6(uniprot-removed-ac)|interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|interpro:IPR011542(SUF system FeS cluster assembly, SufD)|interpro:IPR037284|go:""GO:0016226""(iron-sulfur cluster assembly)|refseq:WP_002211806.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:a7NZuEFgvJhp4nMMr3+0yi9KT8Y9606	rogid:uncY4eypg9zENXaPeJUsdcE+jL4632	intact-crc:3A959D4F1F6C5F2B|rigid:9RMI1F75twuscX+oX9xEgLadZCk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0VD83	uniprotkb:Q7ARD3	intact:EBI-2826617|uniprotkb:Q9NPJ9|uniprotkb:Q8NC15|uniprotkb:Q0VD81|uniprotkb:H3BU97|ensembl:ENSP00000457539.1|intact:EBI-28978080	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:apobr_human(display_long)|uniprotkb:APOBR(gene name)|psi-mi:APOBR(display_short)|uniprotkb:Apolipoprotein B-48 receptor(gene name synonym)|uniprotkb:APOB48R(gene name synonym)|uniprotkb:Apolipoprotein B-100 receptor(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860150|imex:IM-13779-6483	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_061160.3|ensembl:ENSG00000184730.12(gene)|ensembl:ENST00000564831.6(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0006869""(lipid transport)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0030229""(very-low-density lipoprotein particle receptor activity)|go:""GO:0034361""(very-low-density lipoprotein particle)|go:""GO:0034362""(low-density lipoprotein particle)|go:""GO:0042627""(chylomicron)|interpro:IPR026158|reactome:R-HSA-8964046|panther:PTHR15964(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:T2vGmU0ShIcp9xn7DOt3p760qKw9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:D8B0FEDF2E30293C|rigid:dNCb6Uaw4n8OeFXE0Fmxjj7tyJA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZM3	uniprotkb:P30520	intact:EBI-2842197|uniprotkb:Q74YC6	intact:EBI-1042898|uniprotkb:Q96EG7|uniprotkb:B1AQM5|ensembl:ENSP00000355493.3	psi-mi:q8czm3_yerpe(display_long)|uniprotkb:hemN(gene name)|psi-mi:hemN(display_short)|uniprotkb:hemN1(gene name synonym)|uniprotkb:YP_0022(locus name)|uniprotkb:y3807(locus name)	psi-mi:pura2_human(display_long)|uniprotkb:ADSS2(gene name)|psi-mi:ADSS2(display_short)|uniprotkb:ADSS(gene name synonym)|uniprotkb:Adenylosuccinate synthetase, acidic isozyme(gene name synonym)|uniprotkb:Adenylosuccinate synthetase, liver isozyme(gene name synonym)|uniprotkb:IMP--aspartate ligase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860179|imex:IM-13779-6489	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004558(Oxygen-independent coproporphyrinogen III oxidase HemN)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR010723(HemN, C-terminal)|interpro:IPR007197(Radical SAM)|interpro:IPR013785(Aldolase-type TIM barrel)|go:""GO:0004109""(coproporphyrinogen oxidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0051989""(coproporphyrinogen dehydrogenase activity)|interpro:IPR034505"	"refseq:NP_001117.2|ensembl:ENSG00000035687.10(gene)|ensembl:ENST00000366535.4(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0002376""(immune system process)|go:""GO:0004019""(adenylosuccinate synthase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006167""(AMP biosynthetic process)|go:""GO:0006531""(aspartate metabolic process)|go:""GO:0014074""(response to purine-containing compound)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0044208""('de novo' AMP biosynthetic process)|go:""GO:0046040""(IMP metabolic process)|go:""GO:0060359""(response to ammonium ion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071257""(cellular response to electrical stimulus)|interpro:IPR001114(Adenylosuccinate synthetase)|interpro:IPR018220|interpro:IPR027417|interpro:IPR027529|interpro:IPR033128|interpro:IPR042109|interpro:IPR042110|interpro:IPR042111|mint:P30520|rcsb pdb:2V40|reactome:R-HSA-73817|panther:PTHR11846(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:J5m2HbtFIANx5IaV2zvcYnB7hYI632	rogid:Tyydt3Z/JHGYtfY9oc9XfFkDguM9606	intact-crc:CE01672588BAE79C|rigid:GwVBx2TQ2cN0AANhs4/DCV+HtyI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40127	uniprotkb:P30520	intact:EBI-2844091|uniprotkb:Q0WAG2	intact:EBI-1042898|uniprotkb:Q96EG7|uniprotkb:B1AQM5|ensembl:ENSP00000355493.3	psi-mi:cyaa_yerpe(display_long)|uniprotkb:cya(gene name)|psi-mi:cya(display_short)|uniprotkb:cyaA(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:YPO3848(locus name)|uniprotkb:y0382(locus name)|uniprotkb:YP_3199(locus name)	psi-mi:pura2_human(display_long)|uniprotkb:ADSS2(gene name)|psi-mi:ADSS2(display_short)|uniprotkb:ADSS(gene name synonym)|uniprotkb:Adenylosuccinate synthetase, acidic isozyme(gene name synonym)|uniprotkb:Adenylosuccinate synthetase, liver isozyme(gene name synonym)|uniprotkb:IMP--aspartate ligase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860186|imex:IM-13779-6490	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000274(Adenylate cyclase, class-I)|interpro:IPR024686|interpro:IPR024685|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006171""(cAMP biosynthetic process)|refseq:WP_002211468.1|refseq:YP_002348726.1|panther:PTHR38760(orthology-group)"	"refseq:NP_001117.2|ensembl:ENSG00000035687.10(gene)|ensembl:ENST00000366535.4(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0002376""(immune system process)|go:""GO:0004019""(adenylosuccinate synthase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006167""(AMP biosynthetic process)|go:""GO:0006531""(aspartate metabolic process)|go:""GO:0014074""(response to purine-containing compound)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0044208""('de novo' AMP biosynthetic process)|go:""GO:0046040""(IMP metabolic process)|go:""GO:0060359""(response to ammonium ion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071257""(cellular response to electrical stimulus)|interpro:IPR001114(Adenylosuccinate synthetase)|interpro:IPR018220|interpro:IPR027417|interpro:IPR027529|interpro:IPR033128|interpro:IPR042109|interpro:IPR042110|interpro:IPR042111|mint:P30520|rcsb pdb:2V40|reactome:R-HSA-73817|panther:PTHR11846(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l0RzY0/qkJ4UmTdMusK/+DQB0ow632	rogid:Tyydt3Z/JHGYtfY9oc9XfFkDguM9606	intact-crc:060069A818A98E78|rigid:kWbFC7OnSclpKF2yTjW+zBvQnxE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13610	uniprotkb:A0A3N4B749	intact:EBI-1050630|uniprotkb:A8K3R6|uniprotkb:Q7Z3X9|ensembl:ENSP00000387365.3	intact:EBI-2842996|uniprotkb:Q74V98|uniprotkb:Q0WGP3|uniprotkb:Q7CHR5|uniprotkb:A0A384LAC1	psi-mi:pwp1_human(display_long)|uniprotkb:Keratinocyte protein IEF SSP 9502(gene name synonym)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short)	psi-mi:a0a3n4b749_yerpe(display_long)|uniprotkb:YPO1529(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860172|imex:IM-13779-6487	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_008993.1|refseq:NP_001304892.1|ensembl:ENSG00000136045.12(gene)|ensembl:ENST00000412830.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006364""(rRNA processing)|go:""GO:0140713""(histone chaperone activity)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1990889""(histone H4K20me3 reader activity)|go:""GO:2000738""(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q13610|panther:PTHR14091(orthology-group)"	"interpro:IPR010977(Aromatic-L-amino-acid decarboxylase)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002211877.1|go:""GO:0005737""(cytoplasm)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0016831""(carboxy-lyase activity)|go:""GO:0019752""(carboxylic acid metabolic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:YP_002346545.1|panther:PTHR45677(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3LMa4f6IxjpvEoh2Hyu0hHKkY789606	rogid:Uex6pAvRG3FNG1VCbilPXw5bliY632	intact-crc:BB2189AA269E1377|rigid:LSmtgzB6uiEu/0Yy3wu2TIvKYbU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31939	uniprotkb:A0A5P8YCV0	intact:EBI-1048599|uniprotkb:Q13856|uniprotkb:Q53S28|uniprotkb:A8K202|uniprotkb:E9PBU3|ensembl:ENSP00000236959.9	intact:EBI-2847775|uniprotkb:Q74Q84|uniprotkb:Q0WIC7|uniprotkb:Q7CGS8|uniprotkb:A0A384L1X8	psi-mi:pur9_human(display_long)|uniprotkb:ATIC(gene name)|psi-mi:ATIC(display_short)|uniprotkb:PURH(gene name synonym)|uniprotkb:OK/SW-cl.86(orf name)|uniprotkb:AICAR transformylase/inosine monophosphate cyclohydrolase(gene name synonym)	psi-mi:a0a5p8ycv0_yerpe(display_long)|uniprotkb:YPO0913(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860193|imex:IM-13779-6488	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000138363.15(gene)|ensembl:ENST00000236959.14(transcript)|go:""GO:0003360""(brainstem development)|go:""GO:0003937""(IMP cyclohydrolase activity)|go:""GO:0004643""(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|go:""GO:0006177""(GMP biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0021549""(cerebellum development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044208""('de novo' AMP biosynthetic process)|go:""GO:0045296""(cadherin binding)|go:""GO:0046452""(dihydrofolate metabolic process)|go:""GO:0046654""(tetrahydrofolate biosynthetic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097294""('de novo' XMP biosynthetic process)|go:""GO:0098761""(cellular response to interleukin-7)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|mint:P31939|rcsb pdb:1P4R|rcsb pdb:1PKX|rcsb pdb:1PL0|rcsb pdb:5UY8|rcsb pdb:5UZ0|reactome:R-HSA-73817|reactome:R-HSA-9725370|refseq:NP_004035.2|efo:""Orphanet:250977""|panther:PTHR11692(orthology-group)"	"interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|refseq:WP_002209955.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009396""(folic acid-containing compound biosynthetic process)|go:""GO:0030272""(5-formyltetrahydrofolate cyclo-ligase activity)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|interpro:IPR024185|interpro:IPR037171|refseq:YP_002345961.1|panther:PTHR23407(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xe3388w/LOBYgag9P8Gp3IGo9wU9606	rogid:10+1hunnZ1E8GkdgkFMuY64dDRY632	intact-crc:D73FE0B901B0A331|rigid:XWEAkINLUNa3c+DMfQOPlC4Ogkk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZDJ2	uniprotkb:P29350	intact:EBI-2844031|uniprotkb:Q0WDV6	intact:EBI-78260|intact:EBI-28977917|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67|ensembl:ENSP00000326010.9	psi-mi:a2mgh_yerpe(display_long)|uniprotkb:YPO2573(locus name)|uniprotkb:y1143(locus name)|uniprotkb:YP_1141(locus name)	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860240|imex:IM-13779-6493	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021868|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|go:""GO:0004866""(endopeptidase inhibitor activity)|interpro:IPR041203|interpro:IPR041246|interpro:IPR041462|refseq:YP_002347532.1|interpro:IPR051802|panther:PTHR40094(orthology-group)"	"panther:PTHR46257(orthology-group)|dip:DIP-31002N|interpro:IPR036860|efo:""Orphanet:3243""|efo:""Orphanet:538863""|efo:""Orphanet:538866""|efo:""Orphanet:538869""|efo:""Orphanet:538872""|ensembl:ENSG00000111679.17(gene)|ensembl:ENST00000318974.14(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002924""(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033007""(negative regulation of mast cell activation involved in immune response)|go:""GO:0033630""(positive regulation of cell adhesion mediated by integrin)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042105""(alpha-beta T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050732""(negative regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905867""(epididymis development)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR052123|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:3PS5|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|rcsb pdb:8YHI|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-201556|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9705671|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|refseq:XP_011519290.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9FN1refl1me6jgo6ehCPO8MzV8Y632	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	intact-crc:4F8A2C6298256BEA|rigid:s/Opv0mo6ooWpVKRUZ4/3J3aKro	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TB72	uniprotkb:Q8ZJF3	intact:EBI-311190|uniprotkb:O00234|uniprotkb:Q53TV7|uniprotkb:Q8WY43|uniprotkb:Q9HAN2|uniprotkb:B4E2B6|uniprotkb:B3KSL0|uniprotkb:D6W527|ensembl:ENSP00000516061.1	intact:EBI-2850095|uniprotkb:Q0WKE6	psi-mi:pum2_human(display_long)|uniprotkb:PUM2(gene name)|psi-mi:PUM2(display_short)|uniprotkb:KIAA0235(gene name synonym)|uniprotkb:PUMH2(gene name synonym)	psi-mi:gph_yerpe(display_long)|uniprotkb:gph(gene name)|psi-mi:gph(display_short)|uniprotkb:YPO0156(locus name)|uniprotkb:y3939(locus name)|uniprotkb:YP_0158(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860212|imex:IM-13779-6494	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056132.1|refseq:NP_001269681.1|refseq:XP_005262664.1|refseq:XP_005262666.1|refseq:XP_006712036.1|refseq:XP_006712037.1|ensembl:ENSG00000055917.17(gene)|ensembl:ENST00000704930.1(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001942""(hair follicle development)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006417""(regulation of translation)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034063""(stress granule assembly)|go:""GO:0035196""(miRNA processing)|go:""GO:0035198""(miRNA binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048687""(positive regulation of sprouting of injured axon)|go:""GO:0051276""(chromosome organization)|go:""GO:0051983""(regulation of chromosome segregation)|go:""GO:0060612""(adipose tissue development)|go:""GO:0060964""(regulation of miRNA-mediated gene silencing)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0062104""(pumilio-response element binding)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0106222""(lncRNA binding)|rcsb pdb:3Q0Q|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1900246""(positive regulation of RIG-I signaling pathway)|go:""GO:1904580""(regulation of intracellular mRNA localization)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|mint:Q8TB72|rcsb pdb:3Q0R|rcsb pdb:3Q0S|reactome:R-HSA-8951664|refseq:XP_011531021.1|refseq:XP_011531022.1|refseq:XP_011531023.1|refseq:XP_016859190.1|refseq:XP_016859191.1|refseq:XP_016859196.1|refseq:XP_016859197.1|panther:PTHR12537(orthology-group)"	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|interpro:IPR037512|refseq:WP_002208892.1|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006281""(DNA repair)|go:""GO:0008967""(phosphoglycolate phosphatase activity)|go:""GO:0046295""(glycolate biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR036412|interpro:IPR041492|refseq:YP_002345242.1|interpro:IPR050155|panther:PTHR43434(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WOut5XivMQAQkHVKu1wjFTK6ePM9606	rogid:n2m9iPEoLBOpfauijcWx/W/lq+M632	intact-crc:A5B24259DC2A666E|rigid:UGNBk/1Ml6DstPP7p1KptnQs0go	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31939	uniprotkb:A0A380PFZ2	intact:EBI-1048599|uniprotkb:Q13856|uniprotkb:Q53S28|uniprotkb:A8K202|uniprotkb:E9PBU3|ensembl:ENSP00000236959.9	intact:EBI-2860200|uniprotkb:Q74QX6|uniprotkb:Q0WA54|uniprotkb:Q7CFZ9	psi-mi:pur9_human(display_long)|uniprotkb:ATIC(gene name)|psi-mi:ATIC(display_short)|uniprotkb:PURH(gene name synonym)|uniprotkb:OK/SW-cl.86(orf name)|uniprotkb:AICAR transformylase/inosine monophosphate cyclohydrolase(gene name synonym)	psi-mi:a0a380pfz2_yerpe(display_long)|uniprotkb:YPO3963(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860205|imex:IM-13779-6491	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000138363.15(gene)|ensembl:ENST00000236959.14(transcript)|go:""GO:0003360""(brainstem development)|go:""GO:0003937""(IMP cyclohydrolase activity)|go:""GO:0004643""(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|go:""GO:0006177""(GMP biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0021549""(cerebellum development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044208""('de novo' AMP biosynthetic process)|go:""GO:0045296""(cadherin binding)|go:""GO:0046452""(dihydrofolate metabolic process)|go:""GO:0046654""(tetrahydrofolate biosynthetic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097294""('de novo' XMP biosynthetic process)|go:""GO:0098761""(cellular response to interleukin-7)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|mint:P31939|rcsb pdb:1P4R|rcsb pdb:1PKX|rcsb pdb:1PL0|rcsb pdb:5UY8|rcsb pdb:5UZ0|reactome:R-HSA-73817|reactome:R-HSA-9725370|refseq:NP_004035.2|efo:""Orphanet:250977""|panther:PTHR11692(orthology-group)"	"refseq:YP_002348834.1|interpro:IPR001851(Bacterial inner-membrane translocator)|refseq:WP_002209522.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|panther:PTHR32196(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xe3388w/LOBYgag9P8Gp3IGo9wU9606	rogid:1BJOSwh9X3kQ90C2m8mahsGQqcY632	intact-crc:F974C0EDF7B14304|rigid:IMiCGXOjXOn4NZ+MmnO2Q33OO1I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P18433	uniprotkb:Q8D0N9	intact:EBI-2609645|uniprotkb:D3DVX5|uniprotkb:Q14513|uniprotkb:Q7Z2I2|uniprotkb:A8K2G8|uniprotkb:Q96TD9|ensembl:ENSP00000382787.2|intact:EBI-11028029	intact:EBI-2845331|uniprotkb:Q74UJ0	psi-mi:ptpra_human(display_long)|uniprotkb:PTPRA(gene name)|psi-mi:PTPRA(display_short)|uniprotkb:PTPA(gene name synonym)|uniprotkb:PTPRL2(gene name synonym)	psi-mi:q8d0n9_yerpe(display_long)|uniprotkb:pqiB2(gene name)|psi-mi:pqiB2(display_short)|uniprotkb:YP_1726(locus name)|uniprotkb:y1863(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860233|imex:IM-13779-6496	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000132670.21(gene)|ensembl:ENST00000399903.7(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0043235""(receptor complex)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097060""(synaptic membrane)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|interpro:IPR050348|mint:P18433|rcsb pdb:6UZT|reactome:R-HSA-375165|reactome:R-HSA-5673001|refseq:NP_002827.1|refseq:NP_543030.1|refseq:NP_543031.1|panther:PTHR19134(orthology-group)"	"interpro:IPR003399(Mammalian cell entry related)|go:""GO:0016020""(membrane)|interpro:IPR051800"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dWjvj2zG0Kapb8MhDjinV+LpG109606	rogid:ubTQpOsKz5MxAzZCDHdFKkWSofo632	intact-crc:9014770927AB56A1|rigid:QYURCSibhhI6gKJVhKeKnU8UWAs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D050	uniprotkb:Q9UHX1	intact:EBI-2848540|uniprotkb:Q74VU3	intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359.1|ensembl:ENSP00000515511.1	psi-mi:q8d050_yerpe(display_long)|uniprotkb:aspC(gene name)|psi-mi:aspC(display_short)|uniprotkb:y2760(locus name)|uniprotkb:YP_1183(locus name)	"psi-mi:puf60_human(display_long)|uniprotkb:""60 kDa poly(U)-binding-splicing factor""(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860219|imex:IM-13779-6492	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)"	"efo:""Orphanet:508488""|efo:""Orphanet:508498""|dip:DIP-34636N|ensembl:ENSG00000179950.15(gene)|ensembl:ENST00000526683.6(transcript)|ensembl:ENST00000703866.1(transcript)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006376""(mRNA splice site recognition)|go:""GO:0006915""(apoptotic process)|go:""GO:0030054""(cell junction)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|interpro:IPR051974|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|rcsb pdb:3US5|rcsb pdb:3UWT|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|rcsb pdb:6LUR|rcsb pdb:6SLO|rcsb pdb:7Q8A|rcsb pdb:7Z3X|reactome:R-HSA-72163|refseq:NP_001129505.1|refseq:NP_001258025.1|refseq:NP_001258026.1|refseq:NP_001258027.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:XP_016868728.1|refseq:XP_016868729.1|panther:PTHR47330(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PXhfATAXvq73Z2dQc+YovYvMWRY632	rogid:nL6ALA543VdThkempiJTWAOhoNA9606	intact-crc:20923BBA3BBBD1D4|rigid:t65xORytu7tNJQiVJHBpxUAiMQ8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P23467	uniprotkb:Q8Z9U2	intact:EBI-1265766|uniprotkb:B7ZKT0|uniprotkb:C9JX87|uniprotkb:Q14D85|uniprotkb:Q3MIV7|ensembl:ENSP00000261266.5|uniprotkb:B7ZKS8|uniprotkb:F5H3G6	intact:EBI-2843724|uniprotkb:Q0W9T4	psi-mi:ptprb_human(display_long)|uniprotkb:PTPRB(gene name)|psi-mi:PTPRB(display_short)|uniprotkb:PTPB(gene name synonym)|uniprotkb:Vascular endothelial protein tyrosine phosphatase(gene name synonym)	psi-mi:mnme_yerpe(display_long)|uniprotkb:mnmE(gene name)|psi-mi:mnmE(display_short)|uniprotkb:thdF(gene name synonym)|uniprotkb:trmE(gene name synonym)|uniprotkb:YPO4103(locus name)|uniprotkb:y4118(locus name)|uniprotkb:YP_4010(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860226|imex:IM-13779-6495	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001103224.1|refseq:NP_001193900.1|refseq:NP_001193901.1|refseq:NP_002828.3|ensembl:ENSG00000127329.16(gene)|ensembl:ENST00000261266.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0006796""(phosphate-containing compound metabolic process)|go:""GO:0008347""(glial cell migration)|go:""GO:0016311""(dephosphorylation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0035579""(specific granule membrane)|go:""GO:0043235""(receptor complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|interpro:IPR050713|mint:P23467|rcsb pdb:2AHS|rcsb pdb:2H02|rcsb pdb:2H03|rcsb pdb:2H04|rcsb pdb:2HC1|rcsb pdb:2HC2|rcsb pdb:2I3R|rcsb pdb:2I3U|rcsb pdb:2I4E|rcsb pdb:2I4G|rcsb pdb:2I4H|rcsb pdb:2I5X|rcsb pdb:8JBN|rcsb pdb:8JBY|reactome:R-HSA-6798695|refseq:NP_001317133.1|panther:PTHR46957(orthology-group)"	"interpro:IPR018948|interpro:IPR004520(tRNA modification GTPase TrmE)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR025867|interpro:IPR027417|interpro:IPR031168|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0046872""(metal ion binding)|interpro:IPR027266|interpro:IPR027368|refseq:YP_002348954.1|panther:PTHR42714(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:X+GhwOoXfwd3PaFx3UFdQNkNAL89606	rogid:XaI2j4tZS0U65rUmSnAsXuaqAKo632	intact-crc:70BD2E1EF4587A18|rigid:Q3jsyc3Iof0brSf5InOei16wbXI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q9H3S7	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-724478|uniprotkb:Q7KZF8|uniprotkb:Q8N6Z5|uniprotkb:Q9BSR5|uniprotkb:Q9P257|uniprotkb:Q9UG03|uniprotkb:Q9UMZ4|uniprotkb:A8K0D7|ensembl:ENSP00000265562.4	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:ptn23_human(display_long)|uniprotkb:His domain-containing protein tyrosine phosphatase(gene name synonym)|uniprotkb:Protein tyrosine phosphatase TD14(gene name synonym)|uniprotkb:PTPN23(gene name)|psi-mi:PTPN23(display_short)|uniprotkb:KIAA1471(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860257|imex:IM-13779-6499	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"efo:""Orphanet:528084""|ensembl:ENSG00000076201.16(gene)|ensembl:ENST00000265562.5(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0010633""(negative regulation of epithelial cell migration)|go:""GO:0016604""(nuclear body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0032456""(endocytic recycling)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0060271""(cilium assembly)|go:""GO:0061357""(positive regulation of Wnt protein secretion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1903387""(positive regulation of homophilic cell adhesion)|go:""GO:1903393""(positive regulation of adherens junction organization)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004328(BRO1)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR025304|interpro:IPR029021|interpro:IPR038499|mint:Q9H3S7|rcsb pdb:3RAU|rcsb pdb:5CRU|rcsb pdb:5CRV|rcsb pdb:5LM1|rcsb pdb:5LM2|rcsb pdb:5MJY|rcsb pdb:5MJZ|rcsb pdb:5MK0|rcsb pdb:5MK1|rcsb pdb:5MK2|rcsb pdb:5MK3|reactome:R-HSA-9008059|refseq:NP_001291411.1|refseq:NP_056281.1|dip:DIP-29923N|panther:PTHR23030(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:PeqzQLL4J4v9IMuHFBlb+1B4Ujw9606	intact-crc:74EC01F38BECC98E|rigid:8uBZwV94ICTn6CrCDOnXlWyqEPI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H3S7	uniprotkb:Q8D0S2	intact:EBI-724478|uniprotkb:Q7KZF8|uniprotkb:Q8N6Z5|uniprotkb:Q9BSR5|uniprotkb:Q9P257|uniprotkb:Q9UG03|uniprotkb:Q9UMZ4|uniprotkb:A8K0D7|ensembl:ENSP00000265562.4	intact:EBI-2860250	psi-mi:ptn23_human(display_long)|uniprotkb:His domain-containing protein tyrosine phosphatase(gene name synonym)|uniprotkb:Protein tyrosine phosphatase TD14(gene name synonym)|uniprotkb:PTPN23(gene name)|psi-mi:PTPN23(display_short)|uniprotkb:KIAA1471(gene name synonym)	psi-mi:q8d0s2_yerpe(display_long)|uniprotkb:y1672(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860247|imex:IM-13779-6497	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000076201.16(gene)|ensembl:ENST00000265562.5(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0010633""(negative regulation of epithelial cell migration)|go:""GO:0016604""(nuclear body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0032456""(endocytic recycling)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0060271""(cilium assembly)|go:""GO:0061357""(positive regulation of Wnt protein secretion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1903387""(positive regulation of homophilic cell adhesion)|go:""GO:1903393""(positive regulation of adherens junction organization)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004328(BRO1)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR025304|interpro:IPR029021|interpro:IPR038499|mint:Q9H3S7|rcsb pdb:3RAU|rcsb pdb:5CRU|rcsb pdb:5CRV|rcsb pdb:5LM1|rcsb pdb:5LM2|rcsb pdb:5MJY|rcsb pdb:5MJZ|rcsb pdb:5MK0|rcsb pdb:5MK1|rcsb pdb:5MK2|rcsb pdb:5MK3|reactome:R-HSA-9008059|refseq:NP_001291411.1|refseq:NP_056281.1|dip:DIP-29923N|panther:PTHR23030(orthology-group)"	"interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR050903|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR035965|interpro:IPR013655(PAS fold-3)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:PeqzQLL4J4v9IMuHFBlb+1B4Ujw9606	rogid:Ijy2z//5zbVT/OTgKSlRqBBFln8632	intact-crc:AB4EBFBF54B4787B|rigid:EgipX7qmHuhI08C+FQyD6ETMkR8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D131	uniprotkb:P18031	intact:EBI-2858378|uniprotkb:Q74VY8	intact:EBI-968788|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4|ensembl:ENSP00000360683.3	psi-mi:q8d131_yerpe(display_long)|uniprotkb:mviM1(gene name)|psi-mi:mviM1(display_short)|uniprotkb:YP_1131(locus name)|uniprotkb:y1152(locus name)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860280|imex:IM-13779-6498	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR050463|go:""GO:0000166""(nucleotide binding)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR055170|interpro:IPR036291"	"refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N|ensembl:ENSG00000196396.10(gene)|ensembl:ENST00000371621.5(transcript)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0003723""(RNA binding)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0009968""(negative regulation of signal transduction)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030162""(regulation of proteolysis)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031904""(endosome lumen)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033157""(regulation of intracellular protein transport)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035791""(platelet-derived growth factor receptor-beta signaling pathway)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045296""(cadherin binding)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071732""(cellular response to nitric oxide)|go:""GO:0097443""(sorting endosome)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902202""(regulation of hepatocyte growth factor receptor signaling pathway)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903896""(positive regulation of IRE1-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904753""(negative regulation of vascular associated smooth muscle cell migration)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990264""(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:""GO:2000353""(positive regulation of endothelial cell apoptotic process)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR051985|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1AAX|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2F6Z|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:2NT7|rcsb pdb:2NTA|rcsb pdb:2QBP|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2QBS|rcsb pdb:2VEU|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2ZMM|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:3EB1|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QDV|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:6OMY|rcsb pdb:6PFW|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:6XE8|rcsb pdb:6XEF|rcsb pdb:6XEA|rcsb pdb:6XED|rcsb pdb:6XEE|rcsb pdb:6XEG|rcsb pdb:7FQM|rcsb pdb:7FQN|rcsb pdb:7FQO|rcsb pdb:7FQP|rcsb pdb:7FQQ|rcsb pdb:7FQR|rcsb pdb:7FQS|rcsb pdb:7FQT|rcsb pdb:7FQU|rcsb pdb:7FQV|rcsb pdb:7FQW|rcsb pdb:7FQX|rcsb pdb:7FQY|rcsb pdb:7FQZ|rcsb pdb:7FRE|rcsb pdb:7FRF|rcsb pdb:7FRG|rcsb pdb:7FRH|rcsb pdb:7FRI|rcsb pdb:7FRJ|rcsb pdb:7FRK|rcsb pdb:7FRL|rcsb pdb:7FRM|rcsb pdb:7FRN|rcsb pdb:7FRO|rcsb pdb:7FRP|rcsb pdb:7FRQ|rcsb pdb:7FRR|rcsb pdb:7FRS|rcsb pdb:7FRT|rcsb pdb:7FRU|rcsb pdb:7GS7|rcsb pdb:7GS8|rcsb pdb:7GS9|rcsb pdb:7GSA|rcsb pdb:7GSB|rcsb pdb:7GSC|rcsb pdb:7GSD|rcsb pdb:7GSE|rcsb pdb:7GSF|rcsb pdb:7GSG|rcsb pdb:7GSH|rcsb pdb:7GSI|rcsb pdb:7GSJ|rcsb pdb:7GSK|rcsb pdb:7GSL|rcsb pdb:7GSM|rcsb pdb:7GSN|rcsb pdb:7GSO|rcsb pdb:7GSQ|rcsb pdb:7GSR|rcsb pdb:7GST|rcsb pdb:7GSU|rcsb pdb:7GSV|rcsb pdb:7GSW|rcsb pdb:7GSX|rcsb pdb:7GSY|rcsb pdb:7GSZ|rcsb pdb:7GT0|rcsb pdb:7GT1|rcsb pdb:7GT2|rcsb pdb:7GT3|rcsb pdb:7GT4|rcsb pdb:7GT5|rcsb pdb:7GTI|rcsb pdb:7GT6|rcsb pdb:7GT7|rcsb pdb:7GT8|rcsb pdb:7GT9|rcsb pdb:7GTA|rcsb pdb:7GTB|rcsb pdb:7GTC|rcsb pdb:7GTD|rcsb pdb:7GTE|rcsb pdb:7GTF|rcsb pdb:7GTG|rcsb pdb:7GTH|rcsb pdb:7GTJ|rcsb pdb:7GTK|rcsb pdb:7GTL|rcsb pdb:7GTM|rcsb pdb:7GTN|rcsb pdb:7GTO|rcsb pdb:7GTP|rcsb pdb:7GTQ|rcsb pdb:7GTR|rcsb pdb:7GTS|rcsb pdb:7GTT|rcsb pdb:7GTU|rcsb pdb:7GTV|rcsb pdb:7GTW|rcsb pdb:7GTX|rcsb pdb:7GTY|rcsb pdb:7GTZ|rcsb pdb:7GU0|rcsb pdb:7GU1|rcsb pdb:7GU2|rcsb pdb:7GU3|rcsb pdb:7GU4|rcsb pdb:7GU5|rcsb pdb:7GU6|rcsb pdb:7GU7|rcsb pdb:7GU8|rcsb pdb:7GU9|rcsb pdb:7GUA|rcsb pdb:7GUB|rcsb pdb:7GUC|rcsb pdb:7KEN|rcsb pdb:7KEY|rcsb pdb:7KLX|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MKZ|rcsb pdb:7MM1|rcsb pdb:7MN7|rcsb pdb:7MN9|rcsb pdb:7MNA|rcsb pdb:7MNB|rcsb pdb:7MNC|rcsb pdb:7MND|rcsb pdb:7MNE|rcsb pdb:7MNF|rcsb pdb:7MOU|rcsb pdb:7MOV|rcsb pdb:7MOW|rcsb pdb:7RIN|rcsb pdb:7S4F|rcsb pdb:8DU7|rcsb pdb:8EXI|rcsb pdb:8EXJ|rcsb pdb:8EXK|rcsb pdb:8EXM|rcsb pdb:8EXN|rcsb pdb:8EYA|rcsb pdb:8EYB|rcsb pdb:8EYC|rcsb pdb:8F88|rcsb pdb:8G65|rcsb pdb:8G67|rcsb pdb:8G68|rcsb pdb:8G69|rcsb pdb:8G6A|rcsb pdb:8SKL|rcsb pdb:8U1E|rcsb pdb:8XOY|rcsb pdb:9C66|rcsb pdb:9CYO|rcsb pdb:9CYP|rcsb pdb:9CYQ|rcsb pdb:9CYR|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-77387|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-9860927|panther:PTHR46047(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:A5TCBtioM6Hbyj2QQ+aVDQPo8D8632	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	intact-crc:91CDC9C18457AC81|rigid:wCT961wDxhZsoUt6Hkf8B6HyGcY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16825	uniprotkb:A0A2S9PBR0	intact:EBI-2860264|ensembl:ENSP00000330276.3|ensembl:ENSP00000452414.1	intact:EBI-2860272|uniprotkb:Q7CIN4|uniprotkb:Q0WEY3	psi-mi:ptn21_human(display_long)|uniprotkb:PTPN21(gene name)|psi-mi:PTPN21(display_short)|uniprotkb:PTPD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase D1(gene name synonym)	psi-mi:a0a2s9pbr0_yerpe(display_long)|uniprotkb:oppA(gene name)|psi-mi:oppA(display_short)|uniprotkb:YPO2182(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860269|imex:IM-13779-6500	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011534669.1|refseq:NP_008970.2|refseq:XP_005267344.1|ensembl:ENSG00000070778.13(gene)|ensembl:ENST00000328736.7(transcript)|ensembl:ENST00000556564.6(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014392(Protein-tyrosine phosphatase, non-receptor type-14, -21)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR041782|mint:Q16825|rcsb pdb:8GVL|rcsb pdb:8GVV|rcsb pdb:8GWH|rcsb pdb:8GXE|rcsb pdb:8Y8Y|panther:PTHR45706(orthology-group)"	"interpro:IPR000914(Bacterial extracellular solute-binding protein, family 5)|interpro:IPR039424|interpro:IPR023765|refseq:WP_002218177.1|interpro:IPR030678|go:""GO:0015833""(peptide transport)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|go:""GO:1904680""(peptide transmembrane transporter activity)|refseq:YP_002347155.1|panther:PTHR30290(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MCooW5Oa6wUFCJRUWdbBb+DUcNI9606	rogid:pn2AAG+/dGH62sfV+r9JinIZHfc632	intact-crc:0163701615DB7632|rigid:J2TmaPeA4Y+FImSTGNNkLDfG4/0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q3KNS1	uniprotkb:Q8ZIN5	intact:EBI-2860313|uniprotkb:Q6ZU28|uniprotkb:I3L499|uniprotkb:F6LPT1	intact:EBI-2860318|uniprotkb:Q0WJK6	psi-mi:pthd3_human(display_long)|uniprotkb:PTCHD3(gene name)|psi-mi:PTCHD3(display_short)|uniprotkb:PTR(gene name synonym)|uniprotkb:Patched-related protein(gene name synonym)	psi-mi:khse_yerpe(display_long)|uniprotkb:thrB(gene name)|psi-mi:thrB(display_short)|uniprotkb:YPO0460(locus name)|uniprotkb:y3716(locus name)|uniprotkb:YP_3722(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860310|imex:IM-13779-6502	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001030014.2|interpro:IPR051697|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0097225""(sperm midpiece)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|panther:PTHR10796(orthology-group)"	"interpro:IPR006204(GHMP kinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR000870(Homoserine kinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|refseq:WP_002209238.1|go:""GO:0004413""(homoserine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009088""(threonine biosynthetic process)|interpro:IPR036554|refseq:YP_002345532.1|panther:PTHR20861(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/OYuWewa3hX7V7JKktxf7Zii+C09606	rogid:H1wn9dY0xbEJB1q1bQFLwIMygqY632	intact-crc:68881631B569D946|rigid:hFT/NjM1BTZ+/QpASyUP2hjIxZw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1K6	uniprotkb:Q03431	intact:EBI-2860302	intact:EBI-2860297|uniprotkb:Q2M1U3|ensembl:ENSP00000321999.4|ensembl:ENSP00000402723.1|ensembl:ENSP00000411424.1|ensembl:ENSP00000413774.2	psi-mi:q8d1k6_yerpe(display_long)|uniprotkb:wzzE(gene name)|psi-mi:wzzE(display_short)|uniprotkb:y0363(locus name)	psi-mi:pth1r_human(display_long)|uniprotkb:PTH1R(gene name)|psi-mi:PTH1R(display_short)|uniprotkb:PTHR(gene name synonym)|uniprotkb:PTHR1(gene name synonym)|uniprotkb:PTH/PTHrP type I receptor(gene name synonym)|uniprotkb:Parathyroid hormone 1 receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860294|imex:IM-13779-6504	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003856(Lipopolysaccharide biosynthesis)|interpro:IPR032895|interpro:IPR050445|go:""GO:0005886""(plasma membrane)|go:""GO:0009246""(enterobacterial common antigen biosynthetic process)"	"efo:""Orphanet:296""|efo:""Orphanet:33067""|efo:""Orphanet:412206""|efo:""Orphanet:50945""|efo:""Orphanet:79106""|ensembl:ENSG00000160801.14(gene)|ensembl:ENST00000313049.9(transcript)|ensembl:ENST00000418619.5(transcript)|ensembl:ENST00000430002.6(transcript)|ensembl:ENST00000449590.6(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0002076""(osteoblast development)|go:""GO:0004991""(parathyroid hormone receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007187""(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:""GO:0007188""(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0007200""(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008528""(G protein-coupled peptide receptor activity)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0017046""(peptide hormone binding)|go:""GO:0030282""(bone mineralization)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045453""(bone resorption)|go:""GO:0048469""(cell maturation)|go:""GO:0060732""(positive regulation of inositol phosphate biosynthetic process)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR002170(GPCR, family 2, parathyroid hormone receptor)|interpro:IPR017981|interpro:IPR017983|interpro:IPR036445|interpro:IPR050332|mint:Q03431|rcsb pdb:1BL1|rcsb pdb:3C4M|rcsb pdb:3H3G|rcsb pdb:3L2J|rcsb pdb:4Z8J|rcsb pdb:5EMB|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:7UZO|rcsb pdb:7UZP|rcsb pdb:7VVJ|rcsb pdb:7VVK|rcsb pdb:7VVL|rcsb pdb:7VVM|rcsb pdb:7VVN|rcsb pdb:7VVO|rcsb pdb:7Y35|rcsb pdb:7Y36|rcsb pdb:8BIA|rcsb pdb:8BJ0|rcsb pdb:8D51|rcsb pdb:8D52|rcsb pdb:8FLQ|rcsb pdb:8FLR|rcsb pdb:8FLS|rcsb pdb:8FLT|rcsb pdb:8FLU|rcsb pdb:8GW8|rcsb pdb:8HA0|rcsb pdb:8HAF|rcsb pdb:8HAO|rcsb pdb:8JR9|rcsb pdb:9JR2|rcsb pdb:9JR3|reactome:R-HSA-373080|reactome:R-HSA-418555|refseq:NP_000307.1|refseq:NP_001171673.1|refseq:XP_016862422.1|panther:PTHR45620(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dnS1WOEnus6FSM+v/AeLTGNGO08632	rogid:zdoFjG63+GTnmdGVyNf1Gg2rf4k9606	intact-crc:2CE738CDEEBB2507|rigid:5yElGGaO4v9wn+fGyjZuwtgtrds	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P26599	uniprotkb:P42713	intact:EBI-350540|intact:EBI-744534|uniprotkb:Q9BUQ0|ensembl:ENSP00000349428.4	intact:EBI-2855318	psi-mi:ptbp1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:PTB(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym)|uniprotkb:57 kDa RNA-binding protein PPTB-1(gene name synonym)	psi-mi:yscq_yerpe(display_long)|uniprotkb:yscQ(gene name)|psi-mi:yscQ(display_short)|uniprotkb:YPCD1.43(locus name)|uniprotkb:y5035(locus name)|uniprotkb:y0038(locus name)|uniprotkb:YP_pCD40(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860327|imex:IM-13779-6503	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002810.1|refseq:NP_114367.1|refseq:NP_114368.1|ensembl:ENSG00000011304.22(gene)|ensembl:ENST00000356948.11(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006397""(mRNA processing)|go:""GO:0008187""(poly-pyrimidine tract binding)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0033119""(negative regulation of RNA splicing)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045595""(regulation of cell differentiation)|go:""GO:0048025""(negative regulation of mRNA splicing, via spliceosome)|go:""GO:0051148""(negative regulation of muscle cell differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070886""(positive regulation of calcineurin-NFAT signaling cascade)|go:""GO:0075522""(IRES-dependent viral translational initiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR035000|interpro:IPR035001|interpro:IPR035979|mint:P26599|rcsb pdb:1QM9|rcsb pdb:1SJQ|rcsb pdb:1SJR|rcsb pdb:2AD9|rcsb pdb:2ADB|rcsb pdb:2ADC|rcsb pdb:2EVZ|rcsb pdb:2N3O|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|rcsb pdb:8BGF|rcsb pdb:8BWF|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|panther:PTHR15592(orthology-group)"	"refseq:NP_395177.1|refseq:NP_857739.1|refseq:NP_857934.1|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|interpro:IPR003283(Type III secretion system outer membrane O protein)|interpro:IPR013385(Type III secretion system apparatus protein YscQ/HrcQ)|refseq:WP_002212948.1|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0071978""(bacterial-type flagellum-dependent swarming motility)|interpro:IPR036429|panther:PTHR30034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:g5/7bY/TV5l8fS6aBJMg6BNJaWs9606	rogid:6QCEVIThofNCQV+S/cN32USA1WE632	intact-crc:86CBDA91B8746FA2|rigid:zi5xiU/9JqB8q3wpMNczhgXJKnU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1D2	uniprotkb:Q7Z6K3	intact:EBI-2849752|uniprotkb:Q74X70	intact:EBI-2860334|uniprotkb:Q5T7V5|uniprotkb:Q5T7V6|ensembl:ENSP00000344299.4	psi-mi:q8d1d2_yerpe(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:y0687(locus name)	psi-mi:ptar1_human(display_long)|uniprotkb:PTAR1(gene name)|psi-mi:PTAR1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860340|imex:IM-13779-6505	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010214(Transcription termination factor NusA, C-terminal duplication)|interpro:IPR010213(Transcription termination factor NusA)|interpro:IPR025249|interpro:IPR030842|go:""GO:0000166""(nucleotide binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|interpro:IPR036555"	"refseq:NP_001093136.1|ensembl:ENSG00000188647.13(gene)|ensembl:ENST00000340434.5(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0008318""(protein prenyltransferase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:Q7Z6K3|rcsb pdb:6J6X|rcsb pdb:6J74|rcsb pdb:6J7F|rcsb pdb:6J7X|rcsb pdb:6O60|panther:PTHR11129(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YzZfDXwWbJbXKFeHL1SADDhW96Q632	rogid:jWt/x+vt0OvGLJ8PBuy2khuTVgQ9606	intact-crc:86A5053D2D957FFE|rigid:FT+N02MWxXHN/dXnaS2znex8BOQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12923	uniprotkb:Q8D1D4	intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249.2	intact:EBI-2859510|uniprotkb:Q74X74	psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym)	psi-mi:q8d1d4_yerpe(display_long)|uniprotkb:ftsH(gene name synonym)|uniprotkb:hflB(gene name)|psi-mi:hflB(display_short)|uniprotkb:NCTC5923_00800(orf name)|uniprotkb:YP_0581(locus name)|uniprotkb:y0682(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860287|imex:IM-13779-6501	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENSG00000163629.13(gene)|ensembl:ENST00000411767.7(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|interpro:IPR000299(Band 4.1, N-terminal)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0030027""(lamellipodium)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0036312""(phosphatidylinositol 3-kinase regulatory subunit binding)|go:""GO:0044297""(cell body)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097237""(cellular response to toxic substance)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1904890""(negative regulation of excitatory synapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|interpro:IPR052074|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|rcsb pdb:7QCX|rcsb pdb:7QCY|rcsb pdb:7XTY|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-40449N|panther:PTHR46900(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR000642(Peptidase M41)|interpro:IPR027417|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0051301""(cell division)|interpro:IPR037219|interpro:IPR041569"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606	rogid:hxOQM9f6nYka/fP5Gx5H4wtxKzk632	intact-crc:BFCFEB1A9C95574B|rigid:NFJouCbZj9s8Ao4Iw3w7lTifLko	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q06323	uniprotkb:Q8ZIH1	intact:EBI-712149|uniprotkb:H0YNE3|uniprotkb:Q9UEF4|ensembl:ENSP00000206451.6|ensembl:ENSP00000495095.1|uniprotkb:Q6IBM2|uniprotkb:A6NJG9	intact:EBI-2841326|uniprotkb:Q0WJD6	psi-mi:psme1_human(display_long)|uniprotkb:Proteasome activator 28 subunit alpha(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 1(gene name synonym)|uniprotkb:11S regulator complex subunit alpha(gene name synonym)|uniprotkb:Interferon gamma up-regulated I-5111 protein(gene name synonym)|uniprotkb:PSME1(gene name)|psi-mi:PSME1(display_short)|uniprotkb:IFI5111(gene name synonym)	psi-mi:leud_yerpe(display_long)|uniprotkb:leuD(gene name)|psi-mi:leuD(display_short)|uniprotkb:Alpha-IPM isomerase(gene name synonym)|uniprotkb:Isopropylmalate isomerase(gene name synonym)|uniprotkb:YPO0530(locus name)|uniprotkb:y3648(locus name)|uniprotkb:YP_3652(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860368|imex:IM-13779-6507	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006254.1|ensembl:ENSG00000092010.15(gene)|ensembl:ENSG00000284916.2(gene)|ensembl:ENST00000206451.11(transcript)|ensembl:ENST00000645537.2(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008537""(proteasome activator complex)|go:""GO:0019884""(antigen processing and presentation of exogenous antigen)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q06323|rcsb pdb:1AVO|rcsb pdb:7DR6|rcsb pdb:7DRW|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:8CXB|reactome:R-HSA-9907900|refseq:NP_001268457.1|panther:PTHR10660(orthology-group)"	"interpro:IPR004431(3-isopropylmalate dehydratase, small subunit region)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|go:""GO:0003861""(3-isopropylmalate dehydratase activity)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009316""(3-isopropylmalate dehydratase complex)|refseq:WP_002210456.1|refseq:YP_002345602.1|interpro:IPR033940|interpro:IPR050075|panther:PTHR43345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kyTjI3VP2S7Bvwq4R0pJudnlOC09606	rogid:lF0EK380WhlR7ondVqFIwVAnDFQ632	intact-crc:28F8827A99DFCB3D|rigid:O8turaxj6aO9ue0/s3DqDPkOHo4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99460	uniprotkb:P58497	intact:EBI-357874|ensembl:ENSP00000309474.6|ensembl:ENSP00000503068.1|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79	intact:EBI-2840431|uniprotkb:Q0WHQ6	psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym)	psi-mi:mode_yerpe(display_long)|uniprotkb:modE(gene name)|psi-mi:modE(display_short)|uniprotkb:YPO1143(locus name)|uniprotkb:y3040(locus name)|uniprotkb:YP_1017(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860375|imex:IM-13779-6508	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000173692.14(gene)|ensembl:ENST00000308696.11(transcript)|ensembl:ENST00000677230.1(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005838""(proteasome regulatory particle)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034515""(proteasome storage granule)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042176""(regulation of protein catabolic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR040623|interpro:IPR048570|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|panther:PTHR10943(orthology-group)"	"interpro:IPR005116(Transport-associated OB, type 1)|interpro:IPR004606(Molybdenum-pterin binding)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR003725(Molybdenum-binding protein, N-terminal)|interpro:IPR016462(Molybdate-dependent transcriptional regulator, ModE)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0015689""(molybdate ion transport)|go:""GO:0030151""(molybdenum ion binding)|refseq:WP_002210754.1|refseq:YP_002346182.1|interpro:IPR036388|interpro:IPR036390|interpro:IPR051815|panther:PTHR30432(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606	rogid:UOXc5L3bZSzLOIuq9x/17/AMHmM632	intact-crc:1D89FBE478743114|rigid:0fzktNI9Lyg6yzHdQrVPqybJc2Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UL46	uniprotkb:Q8D0P9	intact:EBI-741630|uniprotkb:Q15129|ensembl:ENSP00000216802.5|ensembl:ENSP00000495790.1	intact:EBI-2856577|uniprotkb:Q74UF2	psi-mi:psme2_human(display_long)|uniprotkb:Proteasome activator 28 subunit beta(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 2(gene name synonym)|uniprotkb:11S regulator complex subunit beta(gene name synonym)|uniprotkb:PSME2(gene name)|psi-mi:PSME2(display_short)	psi-mi:q8d0p9_yerpe(display_long)|uniprotkb:aer(gene name)|psi-mi:aer(display_short)|uniprotkb:YP_1774(locus name)|uniprotkb:y1805(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860347|imex:IM-13779-6510	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002809.2|ensembl:ENSG00000100911.16(gene)|ensembl:ENSG00000284889.2(gene)|ensembl:ENST00000216802.10(transcript)|ensembl:ENST00000645325.2(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008537""(proteasome activator complex)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q9UL46|rcsb pdb:7DR6|rcsb pdb:7DRW|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:8CXB|reactome:R-HSA-8950505|reactome:R-HSA-9907900|panther:PTHR10660(orthology-group)"	"interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR051310|interpro:IPR013655(PAS fold-3)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR035965"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:I1OweiKOkWYntSzrxcNfWjAHgx49606	rogid:UQ1nmynYyPCB+ni3UxBTbLxoRNg632	intact-crc:1581EF1EB25E4EC8|rigid:G87QlY/CfgMqS2yr2jRn3jCHJfU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UL46	uniprotkb:Q8ZIY3	intact:EBI-741630|uniprotkb:Q15129|ensembl:ENSP00000216802.5|ensembl:ENSP00000495790.1	intact:EBI-2845647|uniprotkb:Q0WJV9	psi-mi:psme2_human(display_long)|uniprotkb:Proteasome activator 28 subunit beta(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 2(gene name synonym)|uniprotkb:11S regulator complex subunit beta(gene name synonym)|uniprotkb:PSME2(gene name)|psi-mi:PSME2(display_short)	psi-mi:ch60_yerpe(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:mopA(gene name synonym)|uniprotkb:YPO0351(locus name)|uniprotkb:YP_0506(locus name)|uniprotkb:y0609(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860361|imex:IM-13779-6509	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002809.2|ensembl:ENSG00000100911.16(gene)|ensembl:ENSG00000284889.2(gene)|ensembl:ENST00000216802.10(transcript)|ensembl:ENST00000645325.2(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008537""(proteasome activator complex)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q9UL46|rcsb pdb:7DR6|rcsb pdb:7DRW|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:8CXB|reactome:R-HSA-8950505|reactome:R-HSA-9907900|panther:PTHR10660(orthology-group)"	"interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|go:""GO:0005524""(ATP binding)|go:""GO:0009408""(response to heat)|go:""GO:0016853""(isomerase activity)|go:""GO:0042026""(protein refolding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990220""(GroEL-GroES complex)|refseq:WP_002209128.1|interpro:IPR027410|refseq:YP_002345429.1|panther:PTHR45633(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:I1OweiKOkWYntSzrxcNfWjAHgx49606	rogid:Ns3NkyImUYTNcqMXDVXNh0E5DTY632	intact-crc:04ACB5A0B002E0B8|rigid:nKh8LQImk9L2Hg/95zOepO1F1o8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YDE1	uniprotkb:Q9UL46	intact:EBI-2844065|uniprotkb:Q74W55|uniprotkb:Q7CH46|uniprotkb:A0A0H2W1U8	intact:EBI-741630|uniprotkb:Q15129|ensembl:ENSP00000216802.5|ensembl:ENSP00000495790.1	psi-mi:a0a5p8yde1_yerpe(display_long)|uniprotkb:sucA(gene name)|psi-mi:sucA(display_short)|uniprotkb:YPO1113(locus name)	psi-mi:psme2_human(display_long)|uniprotkb:Proteasome activator 28 subunit beta(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 2(gene name synonym)|uniprotkb:11S regulator complex subunit beta(gene name synonym)|uniprotkb:PSME2(gene name)|psi-mi:PSME2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860354|imex:IM-13779-6506	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029061|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|go:""GO:0004591""(""oxoglutarate dehydrogenase (succinyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|refseq:WP_002210726.1|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|refseq:YP_002346156.1|panther:PTHR23152(orthology-group)"	"refseq:NP_002809.2|ensembl:ENSG00000100911.16(gene)|ensembl:ENSG00000284889.2(gene)|ensembl:ENST00000216802.10(transcript)|ensembl:ENST00000645325.2(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008537""(proteasome activator complex)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q9UL46|rcsb pdb:7DR6|rcsb pdb:7DRW|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:8CXB|reactome:R-HSA-8950505|reactome:R-HSA-9907900|panther:PTHR10660(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:w9PJqpc9Yv62WYzCA8FUl99d9lk632	rogid:I1OweiKOkWYntSzrxcNfWjAHgx49606	intact-crc:E782EB0545B1B431|rigid:sF+321hAvobRXOJfJxr4ZCNaCOM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NYI0	uniprotkb:A0A0H2W867	intact:EBI-2798394|uniprotkb:A6NFQ4|uniprotkb:Q6B003|uniprotkb:Q9Y2F1|uniprotkb:E9KL50|intact:EBI-28988041	intact:EBI-2853738	psi-mi:psd3_human(display_long)|uniprotkb:EFA6D(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D(gene name synonym)|uniprotkb:EFA6R(gene name synonym)|uniprotkb:HCA67(gene name synonym)|uniprotkb:KIAA0942(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 67(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 3(gene name synonym)|uniprotkb:PSD3(gene name)|psi-mi:PSD3(display_short)|uniprotkb:Epididymis tissue protein Li 20mP(gene name synonym)	psi-mi:a0a0h2w867_yerpe(display_long)|uniprotkb:fliM(gene name)|psi-mi:fliM(display_short)|uniprotkb:fliM_2(gene name synonym)|uniprotkb:NCTC5923_04508(orf name)|uniprotkb:YP_3023(locus name)|uniprotkb:y3467(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860420|imex:IM-13779-6513	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056125.3|refseq:NP_996792.1|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:Q9NYI0|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0014069""(postsynaptic density)|go:""GO:0032012""(regulation of ARF protein signal transduction)|go:""GO:0032587""(ruffle membrane)|panther:PTHR10663(orthology-group)"	"interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|interpro:IPR036429|uniprotkb:A0A6B3T5K9(uniprot-removed-ac)|refseq:WP_002211446.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wu9g5GmiJva6VGDtz8duECqvI3w9606	rogid:oyGy7f/7t+MADi8Zs5mMlPzsGZk632	intact-crc:A8667B3F07CB6DCD|rigid:bBBcwMizZovpNoeeExKDQYC1nNo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NYI0	uniprotkb:A0A2U2H1G9	intact:EBI-2798394|uniprotkb:A6NFQ4|uniprotkb:Q6B003|uniprotkb:Q9Y2F1|uniprotkb:E9KL50|intact:EBI-28988041	intact:EBI-2860427|uniprotkb:Q74RP9|uniprotkb:A0A0H2W7P5|uniprotkb:Q7CGG9|uniprotkb:A0A3N4B4Z5|uniprotkb:A0A384LGP0	psi-mi:psd3_human(display_long)|uniprotkb:EFA6D(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D(gene name synonym)|uniprotkb:EFA6R(gene name synonym)|uniprotkb:HCA67(gene name synonym)|uniprotkb:KIAA0942(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 67(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 3(gene name synonym)|uniprotkb:PSD3(gene name)|psi-mi:PSD3(display_short)|uniprotkb:Epididymis tissue protein Li 20mP(gene name synonym)	psi-mi:a0a2u2h1g9_yerpe(display_long)|uniprotkb:YPO0659(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860431|imex:IM-13779-6515	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056125.3|refseq:NP_996792.1|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:Q9NYI0|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0014069""(postsynaptic density)|go:""GO:0032012""(regulation of ARF protein signal transduction)|go:""GO:0032587""(ruffle membrane)|panther:PTHR10663(orthology-group)"	"interpro:IPR014436(Extradiol aromatic ring-opening dioxygenase, DODA type)|interpro:IPR004183(Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016701""(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen)|refseq:WP_002212189.1|refseq:YP_002345727.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wu9g5GmiJva6VGDtz8duECqvI3w9606	rogid:IUaXFpI/HmIVIRVSHrjNyP6o7As632	intact-crc:2BB95645A582B1B7|rigid:5f7t90gD0mbHiMJVcJdj77WtAMg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NYI0	uniprotkb:P69972	intact:EBI-2798394|uniprotkb:A6NFQ4|uniprotkb:Q6B003|uniprotkb:Q9Y2F1|uniprotkb:E9KL50|intact:EBI-28988041	intact:EBI-2860400|uniprotkb:Q00926|uniprotkb:Q663I0	psi-mi:psd3_human(display_long)|uniprotkb:EFA6D(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D(gene name synonym)|uniprotkb:EFA6R(gene name synonym)|uniprotkb:HCA67(gene name synonym)|uniprotkb:KIAA0942(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 67(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 3(gene name synonym)|uniprotkb:PSD3(gene name)|psi-mi:PSD3(display_short)|uniprotkb:Epididymis tissue protein Li 20mP(gene name synonym)	psi-mi:yscj_yerpe(display_long)|uniprotkb:yscJ(gene name)|psi-mi:yscJ(display_short)|uniprotkb:lcrKA(gene name synonym)|uniprotkb:ylpB(gene name synonym)|uniprotkb:Low calcium response locus protein KA(gene name synonym)|uniprotkb:YPCD1.59(locus name)|uniprotkb:y5019(locus name)|uniprotkb:y0022(locus name)|uniprotkb:YP_pCD24(locus name)|uniprotkb:Lipoprotein YlpB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860406|imex:IM-13779-6514	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056125.3|refseq:NP_996792.1|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:Q9NYI0|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0014069""(postsynaptic density)|go:""GO:0032012""(regulation of ARF protein signal transduction)|go:""GO:0032587""(ruffle membrane)|panther:PTHR10663(orthology-group)"	"refseq:NP_395193.1|refseq:NP_857723.1|refseq:NP_857918.1|interpro:IPR003282(Type III secretion system lipoprotein HrcJ/YscJ)|interpro:IPR006182(Secretory protein YscJ/FliF)|refseq:WP_002212912.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009306""(protein secretion)|interpro:IPR043427|interpro:IPR045851|panther:PTHR30046(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wu9g5GmiJva6VGDtz8duECqvI3w9606	rogid:PKBdZ+0o1yj/arfe7ax31Dz1Hs0632	intact-crc:27AF6C9D1096D6A4|rigid:DDQPD+T43zdw73gZ9JElGfAEnQ8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NYI0	uniprotkb:Q8D0H6	intact:EBI-2798394|uniprotkb:A6NFQ4|uniprotkb:Q6B003|uniprotkb:Q9Y2F1|uniprotkb:E9KL50|intact:EBI-28988041	intact:EBI-2857816|uniprotkb:Q74TR8	psi-mi:psd3_human(display_long)|uniprotkb:EFA6D(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D(gene name synonym)|uniprotkb:EFA6R(gene name synonym)|uniprotkb:HCA67(gene name synonym)|uniprotkb:KIAA0942(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 67(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 3(gene name synonym)|uniprotkb:PSD3(gene name)|psi-mi:PSD3(display_short)|uniprotkb:Epididymis tissue protein Li 20mP(gene name synonym)	psi-mi:q8d0h6_yerpe(display_long)|uniprotkb:YP_2076(locus name)|uniprotkb:y2122(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860413|imex:IM-13779-6512	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056125.3|refseq:NP_996792.1|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:Q9NYI0|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0014069""(postsynaptic density)|go:""GO:0032012""(regulation of ARF protein signal transduction)|go:""GO:0032587""(ruffle membrane)|panther:PTHR10663(orthology-group)"	interpro:IPR009216(Predicted virulence protein SrfB)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wu9g5GmiJva6VGDtz8duECqvI3w9606	rogid:MtJczcVzgkPo2FuN1Uy2RPZ0F3M632	intact-crc:7D0C7C63AC677AF8|rigid:CgStrjdCXJwA9G1DTRkuoh90OGw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZV1	uniprotkb:Q8TCT7	intact:EBI-2843995	intact:EBI-2860382|uniprotkb:Q8IUH9|uniprotkb:O60365|uniprotkb:Q9P1Z6|uniprotkb:Q9BUY6|uniprotkb:Q9H3M4|uniprotkb:Q9NPN2|uniprotkb:Q567S3|uniprotkb:D6W609|ensembl:ENSP00000478298.1	psi-mi:q8czv1_yerpe(display_long)|uniprotkb:y3335(locus name)	psi-mi:spp2b_human(display_long)|uniprotkb:SPPL2B(gene name)|psi-mi:SPPL2B(display_short)|uniprotkb:IMP4(gene name synonym)|uniprotkb:KIAA1532(gene name synonym)|uniprotkb:PSL1(gene name synonym)|uniprotkb:Intramembrane protease 4(gene name synonym)|uniprotkb:Presenilin-like protein 1(gene name synonym)|uniprotkb:Presenilin homologous protein 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860393|imex:IM-13779-6511	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR021307	"refseq:NP_001070706.1|refseq:NP_694533.1|ensembl:ENSG00000005206.17(gene)|ensembl:ENST00000613503.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0010008""(endosome membrane)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030660""(Golgi-associated vesicle membrane)|go:""GO:0031293""(membrane protein intracellular domain proteolysis)|go:""GO:0033619""(membrane protein proteolysis)|go:""GO:0042500""(aspartic endopeptidase activity, intramembrane cleaving)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0050776""(regulation of immune response)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|interpro:IPR003137(Protease-associated PA)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR007369(Peptidase A22B, signal peptide peptidase)|interpro:IPR046450|mint:Q8TCT7|reactome:R-HSA-5357905|panther:PTHR12174(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mvlSMRwfbr0qayRobyN7vmxNk50632	rogid:RRMP9jnU51hQQubjjEKj1JOHM9o9606	intact-crc:3B899AF80B89A765|rigid:4aizcJ7h+4QLCyS+TbHJacwn10E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0I3	uniprotkb:O60759	intact:EBI-2860455	intact:EBI-997814|intact:EBI-2803304|uniprotkb:Q15630|uniprotkb:Q8NE32|uniprotkb:B4DWH9|ensembl:ENSP00000264192.3	psi-mi:q8d0i3_yerpe(display_long)|uniprotkb:manA(gene name)|psi-mi:manA(display_short)|uniprotkb:Phosphohexomutase(gene name synonym)|uniprotkb:Phosphomannose isomerase(gene name synonym)|uniprotkb:y2105(locus name)	psi-mi:cytip_human(display_long)|uniprotkb:Cytohesin-binding protein HE(gene name synonym)|uniprotkb:Cytohesin binder and regulator(gene name synonym)|uniprotkb:CYTIP(gene name)|psi-mi:CYTIP(display_short)|uniprotkb:PSCDBP(gene name synonym)|uniprotkb:Cytohesin-associated scaffolding protein(gene name synonym)|uniprotkb:Pleckstrin homology Sec7 and coiled-coil domains-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860452|imex:IM-13779-6519	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR001250(Mannose-6-phosphate isomerase, type I)|interpro:IPR016305(Mannose-6-phosphate isomerase)|interpro:IPR018050|interpro:IPR014710(RmlC-like jelly roll fold)|go:""GO:0004476""(mannose-6-phosphate isomerase activity)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009298""(GDP-mannose biosynthetic process)|interpro:IPR049071|interpro:IPR046457|interpro:IPR046458"	"refseq:NP_004279.3|refseq:XP_016860875.1|ensembl:ENSG00000115165.11(gene)|ensembl:ENST00000264192.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0030155""(regulation of cell adhesion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR052122|mint:O60759|rcsb pdb:2Z17|panther:PTHR15963(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wQlmh1sSD+u655e4iGuos8stS+0632	rogid:2gBEQjAfTYfUd3I3QExqEP3zDtQ9606	intact-crc:882C68A371EDE33B|rigid:ycuXss3sH/Hq7cl6TfjZYid9fiI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P28062	uniprotkb:A0A454XXH7	intact:EBI-372294|ensembl:ENSP00000364016.4|ensembl:ENSP00000372723.4|ensembl:ENSP00000394155.2|ensembl:ENSP00000402406.2|ensembl:ENSP00000404585.2|ensembl:ENSP00000406797.2|ensembl:ENSP00000414770.2|uniprotkb:Q29824|uniprotkb:Q96J48|uniprotkb:Q5JNW6|uniprotkb:B0UZC0|intact:EBI-780761|uniprotkb:Q5QNR8	intact:EBI-2851240|uniprotkb:Q74Y15|uniprotkb:A0A0H2W158|uniprotkb:Q7CFV5|uniprotkb:A0A384K924	psi-mi:psb8_human(display_long)|uniprotkb:PSMB8(gene name)|psi-mi:PSMB8(display_short)|uniprotkb:LMP7(gene name synonym)|uniprotkb:RING10(gene name synonym)|uniprotkb:Y2(gene name synonym)|uniprotkb:Proteasome subunit beta-5i(gene name synonym)|uniprotkb:Proteasome component C13(gene name synonym)|uniprotkb:Macropain subunit C13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C13(gene name synonym)|uniprotkb:Low molecular mass protein 7(gene name synonym)|uniprotkb:PSMB5i(gene name synonym)|uniprotkb:Really interesting new gene 10 protein(gene name synonym)	psi-mi:a0a454xxh7_yerpe(display_long)|uniprotkb:YPO0168(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860475|imex:IM-13779-6518	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204264.12(gene)|ensembl:ENSG00000206298.8(gene)|ensembl:ENSG00000226201.6(gene)|ensembl:ENSG00000230669.6(gene)|ensembl:ENSG00000231631.6(gene)|ensembl:ENSG00000235715.6(gene)|ensembl:ENSG00000236443.6(gene)|ensembl:ENST00000374882.8(transcript)|ensembl:ENST00000383236.8(transcript)|ensembl:ENST00000421445.6(transcript)|ensembl:ENST00000429645.6(transcript)|ensembl:ENST00000438442.6(transcript)|ensembl:ENST00000455660.6(transcript)|ensembl:ENST00000457261.6(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004298""(threonine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019774""(proteasome core complex, beta-subunit complex)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0052548""(regulation of endopeptidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990111""(spermatoproteasome complex)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|mint:P28062|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|rcsb pdb:7B12|reactome:R-HSA-909733|reactome:R-HSA-9907900|refseq:NP_004150.1|refseq:NP_683720.2|efo:""Orphanet:324977""|panther:PTHR11599(orthology-group)"	interpro:IPR027417|refseq:WP_002215686.1|interpro:IPR033186|refseq:YP_002345254.1|interpro:IPR051162|panther:PTHR30121(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XSNs073UKpjwL4TejKS9mczVX9I9606	rogid:7T8Io5VjMpoAGWF393x9GYtAK2w632	intact-crc:6606FE2374113A3F|rigid:gGXjQeweSk4tNFqUoWAijL8kYZs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZEC9	uniprotkb:Q9UNM6	intact:EBI-2846779|uniprotkb:Q0WES2	intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186.1	psi-mi:rnfb_yerpe(display_long)|uniprotkb:rnfB(gene name)|psi-mi:rnfB(display_short)|uniprotkb:Rnf electron transport complex subunit B(gene name synonym)|uniprotkb:YPO2245(locus name)|uniprotkb:YP_2043(locus name)|uniprotkb:y2086(locus name)	psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860438|imex:IM-13779-6520	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR010207(Electron transport complex, RnfB)|interpro:IPR016463(Electron transport complex, RnfB, subgroup)|interpro:IPR007202(Putative Fe-S cluster)|refseq:WP_002210596.1|interpro:IPR050294|go:""GO:0005886""(plasma membrane)|go:""GO:0009055""(electron transfer activity)|go:""GO:0022900""(electron transport chain)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:YP_002347216.1|panther:PTHR42859(orthology-group)"	"refseq:NP_002808.3|refseq:NP_787128.2|ensembl:ENSG00000185627.19(gene)|ensembl:ENST00000532097.6(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005838""(proteasome regulatory particle)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007127""(meiosis I)|go:""GO:0008541""(proteasome regulatory particle, lid subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|interpro:IPR054179|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-27576N|panther:PTHR10539(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8AghVg8h4AhMIHX7IMGRPKzPYis632	rogid:iOxE62MMeGx+aqsrir/LukJqeho9606	intact-crc:76477E3630B083D9|rigid:yy2LyyRQqp1vrdGRe7wYgsT2k5A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H0Q2	uniprotkb:O00232	intact:EBI-2849316|uniprotkb:Q74T97|uniprotkb:A0A0H2W5H0|uniprotkb:A0A380SBC9|uniprotkb:Q7CJ44|uniprotkb:A0A384KC05	intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|uniprotkb:A6NP15|ensembl:ENSP00000348442.3	psi-mi:a0a2u2h0q2_yerpe(display_long)|uniprotkb:YPO2473(locus name)	psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860445|imex:IM-13779-6516	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR015045(Protein of unknown function DUF1861)|interpro:IPR023296|refseq:WP_002213840.1|refseq:YP_002347437.1	"efo:""Orphanet:528084""|efo:""Orphanet:529962""|interpro:IPR036388|ensembl:ENSG00000197170.10(gene)|ensembl:ENST00000356126.8(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005838""(proteasome regulatory particle)|go:""GO:0008541""(proteasome regulatory particle, lid subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|interpro:IPR054559|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-5676590|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|refseq:NP_001303270.1|refseq:NP_002807.1|refseq:NP_777360.1|dip:DIP-27549N|panther:PTHR10855(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:O/NA0dkts3mvJMI8kSLzsoLX53I632	rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606	intact-crc:112FFD5AE8B9C593|rigid:raRTCTCJhtysO29lpFfJV5bwrUg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B5A3	uniprotkb:O60759	intact:EBI-2860466|uniprotkb:Q74Q70|uniprotkb:Q7CGA8|uniprotkb:Q0WJB8	intact:EBI-997814|intact:EBI-2803304|uniprotkb:Q15630|uniprotkb:Q8NE32|uniprotkb:B4DWH9|ensembl:ENSP00000264192.3	psi-mi:a0a3n4b5a3_yerpe(display_long)|uniprotkb:ftsI(gene name)|psi-mi:ftsI(display_short)|uniprotkb:Penicillin-binding protein 3(gene name synonym)|uniprotkb:pbpB(gene name synonym)|uniprotkb:YPO0549(locus name)	psi-mi:cytip_human(display_long)|uniprotkb:Cytohesin-binding protein HE(gene name synonym)|uniprotkb:Cytohesin binder and regulator(gene name synonym)|uniprotkb:CYTIP(gene name)|psi-mi:CYTIP(display_short)|uniprotkb:PSCDBP(gene name synonym)|uniprotkb:Cytohesin-associated scaffolding protein(gene name synonym)|uniprotkb:Pleckstrin homology Sec7 and coiled-coil domains-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860463|imex:IM-13779-6517	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|refseq:WP_002210440.1|interpro:IPR050515|go:""GO:0000917""(division septum assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008658""(penicillin binding)|go:""GO:0008955""(peptidoglycan glycosyltransferase activity)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|go:""GO:0071555""(cell wall organization)|interpro:IPR036138|refseq:YP_002345620.1|interpro:IPR037532|rcsb pdb:6SYN|rcsb pdb:6TUD|panther:PTHR30627(orthology-group)"	"refseq:NP_004279.3|refseq:XP_016860875.1|ensembl:ENSG00000115165.11(gene)|ensembl:ENST00000264192.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0030155""(regulation of cell adhesion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR052122|mint:O60759|rcsb pdb:2Z17|panther:PTHR15963(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:e+sE4nM4gBd2xYu/J5UYdl88nsk632	rogid:2gBEQjAfTYfUd3I3QExqEP3zDtQ9606	intact-crc:CBCD3C59BF6BB01F|rigid:0V38ulW0XXl/4zvhR0Uh/FWTNSg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P25786	uniprotkb:Q8ZIC6	intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676.2	intact:EBI-2860508|uniprotkb:Q8CZR0|uniprotkb:Q0WJ87	psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym)|uniprotkb:Proteasome subunit alpha-6(gene name synonym)	psi-mi:uxac_yerpe(display_long)|uniprotkb:uxaC(gene name)|psi-mi:uxaC(display_short)|uniprotkb:Glucuronate isomerase(gene name synonym)|uniprotkb:Uronic isomerase(gene name synonym)|uniprotkb:YPO0579(locus name)|uniprotkb:y3600(locus name)|uniprotkb:YP_2899(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860514|imex:IM-13779-6522	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002777.1|refseq:NP_683877.1|ensembl:ENSG00000129084.19(gene)|ensembl:ENST00000396394.7(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002376""(immune system process)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019773""(proteasome core complex, alpha-subunit complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|interpro:IPR050115|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM3|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29369N|panther:PTHR11599(orthology-group)"	"interpro:IPR003766(Glucuronate isomerase)|refseq:WP_002210410.1|interpro:IPR032466|go:""GO:0008880""(glucuronate isomerase activity)|go:""GO:0019698""(D-galacturonate catabolic process)|go:""GO:0042840""(D-glucuronate catabolic process)|refseq:YP_002345651.1|panther:PTHR30068(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606	rogid:xvb/gj4dlbyJ5YEc5bnU6UL77to632	intact-crc:2C840230B940417F|rigid:5lWC+pu8nYFOf7H7aTxtZMWSS0M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PKV8	uniprotkb:P60900	intact:EBI-2859198|uniprotkb:Q74WD4|uniprotkb:Q0WHK6|uniprotkb:Q7CH84|uniprotkb:A0A384KBV6	intact:EBI-357793|ensembl:ENSP00000261479.4|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9	psi-mi:a0a2s9pkv8_yerpe(display_long)|uniprotkb:YPO1194(locus name)	psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym)|uniprotkb:Proteasome subunit alpha-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860501|imex:IM-13779-6524	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001763(Rhodanese-like)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|refseq:WP_002210799.1|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0016784""(3-mercaptopyruvate sulfurtransferase activity)|interpro:IPR036873|refseq:YP_002346232.1|interpro:IPR045078|panther:PTHR11364(orthology-group)"	"refseq:NP_002782.1|ensembl:ENSG00000100902.11(gene)|ensembl:ENST00000261479.9(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0005840""(ribosome)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019773""(proteasome core complex, alpha-subunit complex)|go:""GO:0030016""(myofibril)|go:""GO:0030017""(sarcomere)|go:""GO:0035639""(purine ribonucleoside triphosphate binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|interpro:IPR050115|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM3|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|panther:PTHR11599(orthology-group)|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:NP_001269161.1|refseq:XP_016876957.1|dip:DIP-29367N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:tC9S/oaqk3d0afXfuawLwoksqPQ632	rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606	intact-crc:20588CBBB6D3AC7B|rigid:1o6EHuXIrCIYxnjmmMgnRCHl7IQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46355	uniprotkb:Q99436	intact:EBI-2860482|uniprotkb:Q0WAG1	intact:EBI-603319|uniprotkb:Q96AG8|uniprotkb:Q9BWA7|uniprotkb:Q5TBG6|ensembl:ENSP00000259457.3|uniprotkb:B4E0P1	psi-mi:hem3_yerpe(display_long)|uniprotkb:hemC(gene name)|psi-mi:hemC(display_short)|uniprotkb:Hydroxymethylbilane synthase(gene name synonym)|uniprotkb:Pre-uroporphyrinogen synthase(gene name synonym)|uniprotkb:YPO3849(locus name)|uniprotkb:y0381(locus name)|uniprotkb:YP_3197(locus name)	psi-mi:psb7_human(display_long)|uniprotkb:PSMB7(gene name)|psi-mi:PSMB7(display_short)|uniprotkb:Proteasome subunit Z(gene name synonym)|uniprotkb:Macropain chain Z(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain Z(gene name synonym)|uniprotkb:Z(gene name synonym)|uniprotkb:Proteasome subunit beta-2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860487|imex:IM-13779-6521	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000860(Tetrapyrrole biosynthesis, hydroxymethylbilane synthase)|interpro:IPR022419|interpro:IPR022417|interpro:IPR022418|refseq:WP_002211465.1|go:""GO:0004418""(hydroxymethylbilane synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0006783""(heme biosynthetic process)|interpro:IPR036803|refseq:YP_002348727.1|panther:PTHR11557(orthology-group)"	"refseq:NP_002790.1|ensembl:ENSG00000136930.13(gene)|ensembl:ENST00000259457.8(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004298""(threonine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0016604""(nuclear body)|go:""GO:0019774""(proteasome core complex, beta-subunit complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|mint:Q99436|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:7NAP|rcsb pdb:6HUV|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-33843N|panther:PTHR11599(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:krvqhTt20EZ6UKb/Xzvv9+nk5C0632	rogid:w880QftOor3RdaGvhCup7apz2OM9606	intact-crc:F9141819B73515E9|rigid:IVU9z8OBDPPyyHilqsP015QxExI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1L3	uniprotkb:O14818	intact:EBI-2848215	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|ensembl:ENSP00000359910.4|uniprotkb:Q5JXJ2	psi-mi:q8d1l3_yerpe(display_long)|uniprotkb:ilvE(gene name)|psi-mi:ilvE(display_short)|uniprotkb:y0337(locus name)	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)|uniprotkb:Proteasome subunit alpha-4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860494|imex:IM-13779-6523	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR018300|interpro:IPR005785(Branched-chain amino acid aminotransferase I)|interpro:IPR043131|interpro:IPR043132|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0052655""(L-valine-2-oxoglutarate transaminase activity)|go:""GO:0052656""(L-isoleucine-2-oxoglutarate transaminase activity)|interpro:IPR033939|interpro:IPR036038|interpro:IPR050571"	"refseq:NP_002783.1|ensembl:ENSG00000101182.15(gene)|ensembl:ENST00000370873.9(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019773""(proteasome core complex, alpha-subunit complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR050115|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM3|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29363N|panther:PTHR11599(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:JAIOxo2Y3yD5UWLnGFqrvcdTTQM632	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	intact-crc:5E3D20E17E488882|rigid:LFQ0JAsnpR/4d8u16PCzcbNahI8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35998	uniprotkb:A0A2U2GV98	intact:EBI-359710|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644.3|ensembl:ENSP00000391211.1|ensembl:ENSP00000502939.1|ensembl:ENSP00000503179.1|ensembl:ENSP00000504608.1|uniprotkb:B7Z5E2	intact:EBI-2842935|uniprotkb:Q0WA52|uniprotkb:Q7CG01|uniprotkb:A0A380PFZ4|uniprotkb:A0A384KIG3	psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:a0a2u2gv98_yerpe(display_long)|uniprotkb:YPO3965(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860553|imex:IM-13779-6529	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191382.1|refseq:NP_002794.1|panther:PTHR23073(orthology-group)|ensembl:ENSG00000161057.13(gene)|ensembl:ENST00000292644.5(transcript)|ensembl:ENST00000435765.5(transcript)|ensembl:ENST00000678493.1(transcript)|ensembl:ENST00000679205.1(transcript)|ensembl:ENST00000679341.1(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0000932""(P-body)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR041569|interpro:IPR048723|interpro:IPR050221|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-27554N"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR000014(PAS)|interpro:IPR005467(Signal transduction histidine kinase, core)|refseq:WP_002209524.1|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0016020""(membrane)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|refseq:YP_002348836.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606	rogid:l6f5EnoNPBCpn3IKEDOJAOvm7+w632	intact-crc:C2D55800CF500D67|rigid:1M9dmH+IvgbPUwUYWwdyWjHkVRc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P25786	uniprotkb:A0A380PFB0	intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676.2	intact:EBI-2860521|uniprotkb:Q74SD4|uniprotkb:A0A0H2W679|uniprotkb:Q7CJJ2|uniprotkb:A0A384KDC0	psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym)|uniprotkb:Proteasome subunit alpha-6(gene name synonym)	psi-mi:a0a380pfb0_yerpe(display_long)|uniprotkb:YPO3058(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860525|imex:IM-13779-6525	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002777.1|refseq:NP_683877.1|ensembl:ENSG00000129084.19(gene)|ensembl:ENST00000396394.7(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002376""(immune system process)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019773""(proteasome core complex, alpha-subunit complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|interpro:IPR050115|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM3|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29369N|panther:PTHR11599(orthology-group)"	"interpro:IPR007343(Protein of unknown function, zinc metallopeptidase putative)|refseq:WP_002208554.1|go:""GO:0016020""(membrane)|refseq:YP_002347978.1|panther:PTHR30168(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606	rogid:KVJTtYNUK01KB2kjhwZ2dSyHr40632	intact-crc:8F62AAA1055D2895|rigid:4zN+eJvn0gnKShUiSHywOHGiXdo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P25786	uniprotkb:Q7ARD3	intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676.2	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym)|uniprotkb:Proteasome subunit alpha-6(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860532|imex:IM-13779-6528	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002777.1|refseq:NP_683877.1|ensembl:ENSG00000129084.19(gene)|ensembl:ENST00000396394.7(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002376""(immune system process)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005839""(proteasome core complex)|go:""GO:0019773""(proteasome core complex, alpha-subunit complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|interpro:IPR050115|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7B12|rcsb pdb:7LXV|rcsb pdb:7NAN|rcsb pdb:7NAO|rcsb pdb:7NAP|rcsb pdb:7NAQ|rcsb pdb:7NHT|rcsb pdb:7PG9|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7V5G|rcsb pdb:7V5M|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8BZL|rcsb pdb:8CVR|rcsb pdb:8CVS|rcsb pdb:8CVT|rcsb pdb:8CXB|rcsb pdb:8QYJ|rcsb pdb:8QYL|rcsb pdb:8QYM|rcsb pdb:8QYN|rcsb pdb:8QYO|rcsb pdb:8QYS|rcsb pdb:8QZ9|rcsb pdb:8TM3|rcsb pdb:8TM4|rcsb pdb:8TM5|rcsb pdb:8TM6|rcsb pdb:8UD9|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29369N|panther:PTHR11599(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:3DE2E6C2676ED2D5|rigid:pa+EhdhHLiT/4h/ncLrgJ37h9wM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG8	uniprotkb:P35998	intact:EBI-2849252|uniprotkb:Q0WIB1	intact:EBI-359710|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644.3|ensembl:ENSP00000391211.1|ensembl:ENSP00000502939.1|ensembl:ENSP00000503179.1|ensembl:ENSP00000504608.1|uniprotkb:B7Z5E2	psi-mi:spea_yerpe(display_long)|uniprotkb:speA(gene name)|psi-mi:speA(display_short)|uniprotkb:YPO0929(locus name)|uniprotkb:y3313(locus name)|uniprotkb:YP_3513(locus name)	psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860546|imex:IM-13779-6527	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR002985(Arginine decarboxylase)|interpro:IPR022657|interpro:IPR022644|interpro:IPR022653|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|interpro:IPR029066|interpro:IPR040634|go:""GO:0006527""(arginine catabolic process)|go:""GO:0008295""(spermidine biosynthetic process)|go:""GO:0008792""(arginine decarboxylase activity)|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0046872""(metal ion binding)|interpro:IPR041128|refseq:WP_002209969.1|refseq:YP_002345977.1|panther:PTHR43295(orthology-group)"	"refseq:NP_001191382.1|refseq:NP_002794.1|panther:PTHR23073(orthology-group)|ensembl:ENSG00000161057.13(gene)|ensembl:ENST00000292644.5(transcript)|ensembl:ENST00000435765.5(transcript)|ensembl:ENST00000678493.1(transcript)|ensembl:ENST00000679205.1(transcript)|ensembl:ENST00000679341.1(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0000932""(P-body)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR041569|interpro:IPR048723|interpro:IPR050221|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-27554N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:WJK/NuC1y1WJhbzgBDwly+QaYwA632	rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606	intact-crc:6A50B5529DAF353F|rigid:D95V4Ld5lxu3TxYCOrgDGRst3Wc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5L2Q1	uniprotkb:P62195	intact:EBI-2845751	intact:EBI-357745|ensembl:ENSP00000310572.6|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3	psi-mi:a0a3g5l2q1_yerpe(display_long)|uniprotkb:rcsD_1(gene name)|psi-mi:rcsD_1(display_short)|uniprotkb:NCTC5923_01909(orf name)|uniprotkb:y2968(locus name)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860539|imex:IM-13779-6526	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T660(uniprot-removed-ac)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036890|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0016020""(membrane)|go:""GO:0016740""(transferase activity)|refseq:WP_002216093.1"	"ensembl:ENSG00000087191.14(gene)|ensembl:ENST00000310144.11(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008134""(transcription factor binding)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031531""(thyrotropin-releasing hormone receptor binding)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|panther:PTHR23073(orthology-group)|refseq:NP_001186092.1|refseq:NP_002796.4|dip:DIP-36645N"	"psi-mi:""MI:0469""(intact)"	-	crc64:29C6410C4A85A7F7	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:r4uXUojxy6U1CFud51vTXRXZz/k632	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	intact-crc:A987020D4966C032|rigid:3U8sKRao41yi/oO9kCipEHlr8uQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6P2Q9	uniprotkb:Q8CZQ9	intact:EBI-538479|uniprotkb:O14547|uniprotkb:O75965|ensembl:ENSP00000304350.6|ensembl:ENSP00000460348.1|ensembl:ENSP00000479194.1|ensembl:ENSP00000488611.1	intact:EBI-2852846|uniprotkb:Q74RW8	psi-mi:prp8_human(display_long)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:PRP8 homolog(gene name synonym)|uniprotkb:220 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:p220(gene name synonym)|uniprotkb:PRPC8(gene name synonym)|uniprotkb:PRPF8(gene name)|psi-mi:PRPF8(display_short)	psi-mi:q8czq9_yerpe(display_long)|uniprotkb:y3602(locus name)|uniprotkb:exuR(gene name)|psi-mi:exuR(display_short)|uniprotkb:YP_2896(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860598|imex:IM-13779-6532	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000174231.18(gene)|ensembl:ENSG00000274442.2(gene)|ensembl:ENST00000304992.11(transcript)|ensembl:ENST00000572621.5(transcript)|ensembl:ENST00000614672.2(transcript)|ensembl:ENST00000634039.1(transcript)|go:""GO:0000244""(spliceosomal tri-snRNP complex assembly)|go:""GO:0000375""(RNA splicing, via transesterification reactions)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005682""(U5 snRNP)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0030619""(U1 snRNA binding)|go:""GO:0030620""(U2 snRNA binding)|go:""GO:0030623""(U5 snRNA binding)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071006""(U2-type catalytic step 1 spliceosome)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097157""(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q6P2Q9|rcsb pdb:3E9L|rcsb pdb:3ENB|rcsb pdb:3JCR|rcsb pdb:3LRU|rcsb pdb:4JK7|rcsb pdb:4JK8|rcsb pdb:4JK9|rcsb pdb:4JKA|rcsb pdb:4JKB|rcsb pdb:4JKC|rcsb pdb:4JKD|rcsb pdb:4JKE|rcsb pdb:4JKF|rcsb pdb:4JKG|rcsb pdb:4JKH|rcsb pdb:4KIT|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|rcsb pdb:7OS2|rcsb pdb:7PJH|rcsb pdb:7PX3|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8BC8|rcsb pdb:8BC9|rcsb pdb:8BCA|rcsb pdb:8BCB|rcsb pdb:8BCC|rcsb pdb:8BCD|rcsb pdb:8BCE|rcsb pdb:8BCF|rcsb pdb:8BCG|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8Q7N|rcsb pdb:8Q7Q|rcsb pdb:8Q7V|rcsb pdb:8Q7W|rcsb pdb:8Q7X|rcsb pdb:8Q91|rcsb pdb:8QO9|rcsb pdb:8QOZ|rcsb pdb:8QP8|rcsb pdb:8QP9|rcsb pdb:8QPA|rcsb pdb:8QPB|rcsb pdb:8QPE|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RC0|rcsb pdb:8RM5|rcsb pdb:8RO2|rcsb pdb:8Y6O|rcsb pdb:9FMD|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_006436.3|dip:DIP-29614N|efo:""Orphanet:528084""|efo:""Orphanet:791""|panther:PTHR11140(orthology-group)"	"interpro:IPR011711(GntR, C-terminal)|interpro:IPR000524(Bacterial regulatory protein GntR, HTH)|interpro:IPR008920(Fatty acid responsive transcription factor FadR, C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:I0ot8b3pvieXRI66omFm145sGVA9606	rogid:RD2sxgq5tm9YnJVsIx4EdMD3/Uw632	intact-crc:AD57EB4C927862DC|rigid:/LpGLfWXQcfUaI1BiPgS7wgvHJI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YDR4	uniprotkb:P79522	intact:EBI-2860586|uniprotkb:Q74WD8|uniprotkb:Q0WHK1|uniprotkb:Q7CH88|uniprotkb:A0A384L6S5	intact:EBI-2803328|uniprotkb:Q5RJB5|uniprotkb:Q5STN6|uniprotkb:A1A4H4|ensembl:ENSP00000365744.4|ensembl:ENSP00000373086.4|ensembl:ENSP00000392826.2|ensembl:ENSP00000396416.2|ensembl:ENSP00000398352.2|ensembl:ENSP00000402596.2|ensembl:ENSP00000415432.2	psi-mi:a0a5p8ydr4_yerpe(display_long)|uniprotkb:YPO1201(locus name)	psi-mi:prr3_human(display_long)|uniprotkb:CAT56(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT56(gene name synonym)|uniprotkb:PRR3(gene name)|psi-mi:PRR3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860591|imex:IM-13779-6531	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005308(Orn/Lys/Arg decarboxylase, N-terminal)|interpro:IPR011193(Ornithine/lysine/arginine decarboxylase)|interpro:IPR000310(Orn/Lys/Arg decarboxylase, major region)|interpro:IPR008286(Orn/Lys/Arg decarboxylase, C-terminal)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002210805.1|go:""GO:0005829""(cytosol)|go:""GO:0006527""(arginine catabolic process)|go:""GO:0008792""(arginine decarboxylase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR036633|refseq:YP_002346237.1|panther:PTHR45229(orthology-group)"	"refseq:NP_079539.2|ensembl:ENSG00000204576.12(gene)|ensembl:ENSG00000206491.12(gene)|ensembl:ENSG00000223766.10(gene)|ensembl:ENSG00000223887.10(gene)|ensembl:ENSG00000228186.10(gene)|ensembl:ENSG00000229202.10(gene)|ensembl:ENSG00000233564.10(gene)|ensembl:ENST00000376560.8(transcript)|ensembl:ENST00000383592.8(transcript)|ensembl:ENST00000427729.6(transcript)|ensembl:ENST00000432371.6(transcript)|ensembl:ENST00000449754.6(transcript)|ensembl:ENST00000453232.6(transcript)|ensembl:ENST00000454399.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR042805|panther:PTHR47398(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9A69vMd4aUh4omR1oSM0/w+bz0Y632	rogid:bcAKyQnrxJvEB6z7wAfU7MxJyRQ9606	intact-crc:0C7F0FD1D8E1C4D9|rigid:L0I637Ttk0O+CDoKKp4Ons8lwnQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43686	uniprotkb:A0A2U2H045	intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812.1|ensembl:ENSP00000487367.1	intact:EBI-2860567|uniprotkb:Q74U11|uniprotkb:Q0WF16|uniprotkb:Q7CIG7|uniprotkb:A0A0H2W4Y2|uniprotkb:A0A384KMX6	psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:a0a2u2h045_yerpe(display_long)|uniprotkb:YPO2145(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860572|imex:IM-13779-6530	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006494.1|refseq:NP_694546.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|ensembl:ENSG00000013275.8(gene)|ensembl:ENSG00000281221.3(gene)|ensembl:ENST00000157812.7(transcript)|ensembl:ENST00000629691.3(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29274N|panther:PTHR23073(orthology-group)"	interpro:IPR007390(Sporulation stage V, protein R)|refseq:WP_002211687.1|refseq:YP_002347122.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606	rogid:hVWFo5xBv+72QfFLl/7gk5BPipo632	intact-crc:FFB0E09F2E5B7F1B|rigid:tOCmWel8UlbNPHKQDx4MiXOG5nQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43686	uniprotkb:A0A3N4AWI2	intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812.1|ensembl:ENSP00000487367.1	intact:EBI-2850800|uniprotkb:Q74PQ4|uniprotkb:Q0WB69|uniprotkb:Q7CL85|uniprotkb:A0A384LA61	psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:a0a3n4awi2_yerpe(display_long)|uniprotkb:ntrA(gene name synonym)|uniprotkb:rpoN(gene name synonym)|uniprotkb:YPO3582(locus name)|uniprotkb:glnF(gene name)|psi-mi:glnF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860560|imex:IM-13779-6534	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006494.1|refseq:NP_694546.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|ensembl:ENSG00000013275.8(gene)|ensembl:ENSG00000281221.3(gene)|ensembl:ENST00000157812.7(transcript)|ensembl:ENST00000629691.3(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-29274N|panther:PTHR23073(orthology-group)"	"interpro:IPR000394(RNA polymerase sigma factor 54)|interpro:IPR007046(RNA polymerase sigma factor 54, core-binding)|interpro:IPR007634(RNA polymerase sigma factor 54, DNA-binding)|refseq:WP_002210115.1|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001216""(DNA-binding transcription activator activity)|go:""GO:0003677""(DNA binding)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0016987""(sigma factor activity)|interpro:IPR038709|refseq:YP_002348469.1|panther:PTHR32248(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606	rogid:zdzEhy+OLn0kaYS9XKuSOj5MMBM632	intact-crc:89A0867401F1C376|rigid:ac19Nf8v1tdkm6dWnlGsr/Dtt4U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17980	uniprotkb:Q0WJG6	intact:EBI-359720|uniprotkb:Q3B757|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1|ensembl:ENSP00000298852.3|ensembl:ENSP00000481029.1	intact:EBI-2842715|uniprotkb:Q74Q32|uniprotkb:Q7CG90|uniprotkb:A0A0H2W8G8	psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym)	psi-mi:q0wjg6_yerpe(display_long)|uniprotkb:YPO0499(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860579|imex:IM-13779-6533	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002795.2|ensembl:ENSG00000165916.9(gene)|ensembl:ENST00000298852.8(transcript)|ensembl:ENST00000619920.4(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0000932""(P-body)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043921""(modulation by host of viral transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|dip:DIP-27555N|panther:PTHR23073(orthology-group)"	interpro:IPR010657(ImpA, N-terminal)|refseq:WP_002210482.1|interpro:IPR017740(Type VI secretion system-associated, ImpA)|refseq:YP_002345572.1|panther:PTHR37951(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606	rogid:uNdFAQfLnIba3iBFtXgVG6+OjM8632	intact-crc:468A6166AAB52F99|rigid:8WbBaLzSSYwMhaylVbZwX4IwnZI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W5A0	uniprotkb:P07737	intact:EBI-2860643|uniprotkb:Q74TI3|uniprotkb:Q7CIS3|uniprotkb:A0A380SAX2|uniprotkb:Q0WED4	intact:EBI-713780|uniprotkb:Q53Y44|ensembl:ENSP00000225655.5	psi-mi:a0a0h2w5a0_yerpe(display_long)|uniprotkb:YPO2388(locus name)	psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860648|imex:IM-13779-6539	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|refseq:WP_002210942.1|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|refseq:YP_002347354.1"	"ensembl:ENSG00000108518.8(gene)|ensembl:ENST00000225655.6(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0003785""(actin monomer binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030837""(negative regulation of actin filament polymerization)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032232""(negative regulation of actin filament bundle assembly)|go:""GO:0032233""(positive regulation of actin filament bundle assembly)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050821""(protein stabilization)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0060074""(synapse maturation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0072562""(blood microparticle)|go:""GO:0098885""(modification of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900029""(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|interpro:IPR048278|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|rcsb pdb:7P1H|rcsb pdb:8BJH|rcsb pdb:8BJI|rcsb pdb:8BJJ|rcsb pdb:8BR0|rcsb pdb:8RTY|rcsb pdb:9AZP|reactome:R-HSA-114608|reactome:R-HSA-376176|reactome:R-HSA-4086400|reactome:R-HSA-5663220|refseq:NP_005013.1|dip:DIP-30N|efo:""Orphanet:803""|panther:PTHR13936(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:qusIJwX33yQEbGFFOo0bTmjGhto632	rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606	intact-crc:6AC210C55994E625|rigid:ZAs1J+Bw1ktbvTURIs5klnyep/Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YKZ2	uniprotkb:Q92620	intact:EBI-2860622|uniprotkb:Q74Q71|uniprotkb:Q0WJB6|uniprotkb:Q7CGA9|uniprotkb:A0A384LCM3	intact:EBI-1043041|uniprotkb:O75212|uniprotkb:Q96HN7|uniprotkb:D3DWS7|uniprotkb:B4DVG8|ensembl:ENSP00000268482.3	psi-mi:a0a5p8ykz2_yerpe(display_long)|uniprotkb:mra(gene name)|psi-mi:mra(display_short)|uniprotkb:D-alanyl-D-alanine-adding enzyme(gene name synonym)|uniprotkb:murF(gene name synonym)|uniprotkb:YPO0551(locus name)	psi-mi:prp16_human(display_long)|uniprotkb:DHX38(gene name)|psi-mi:DHX38(display_short)|uniprotkb:DDX38(gene name synonym)|uniprotkb:KIAA0224(gene name synonym)|uniprotkb:PRP16(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DHX38(gene name synonym)|uniprotkb:DEAH box protein 38(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860619|imex:IM-13779-6536	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005863(UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase)|refseq:WP_002210438.1|interpro:IPR051046|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008766""(UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0047480""(UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity)|go:""GO:0051301""(cell division)|go:""GO:0071555""(cell wall organization)|interpro:IPR035911|interpro:IPR036565|interpro:IPR036615|refseq:YP_002345622.1|panther:PTHR43024(orthology-group)"	"efo:""Orphanet:791""|ensembl:ENSG00000140829.12(gene)|ensembl:ENST00000268482.8(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034458""(3'-5' RNA helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR048333|mint:Q92620|rcsb pdb:5YZG|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:8I0W|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_054722.2|refseq:XP_011521786.1|refseq:XP_011521787.1|panther:PTHR18934(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fdMeHvUVX+djYjbRWAsbMX0u/YA632	rogid:miHZNGhDUIz9imwhlPz2tIsCNLs9606	intact-crc:D2E00530AF530685|rigid:FVnkXBWS4czz6Pz09JuwIqwAdaA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG7	uniprotkb:Q6P2Q9	intact:EBI-2843887|uniprotkb:Q0WIB0	intact:EBI-538479|uniprotkb:O14547|uniprotkb:O75965|ensembl:ENSP00000304350.6|ensembl:ENSP00000460348.1|ensembl:ENSP00000479194.1|ensembl:ENSP00000488611.1	psi-mi:metk_yerpe(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:MAT(gene name synonym)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:YPO0931(locus name)|uniprotkb:y3314(locus name)|uniprotkb:YP_3512(locus name)	psi-mi:prp8_human(display_long)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:PRP8 homolog(gene name synonym)|uniprotkb:220 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:p220(gene name synonym)|uniprotkb:PRPC8(gene name synonym)|uniprotkb:PRPF8(gene name)|psi-mi:PRPF8(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860605|imex:IM-13779-6535	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|refseq:WP_002209971.1|refseq:YP_002345978.1|panther:PTHR11964(orthology-group)"	"ensembl:ENSG00000174231.18(gene)|ensembl:ENSG00000274442.2(gene)|ensembl:ENST00000304992.11(transcript)|ensembl:ENST00000572621.5(transcript)|ensembl:ENST00000614672.2(transcript)|ensembl:ENST00000634039.1(transcript)|go:""GO:0000244""(spliceosomal tri-snRNP complex assembly)|go:""GO:0000375""(RNA splicing, via transesterification reactions)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005682""(U5 snRNP)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0030619""(U1 snRNA binding)|go:""GO:0030620""(U2 snRNA binding)|go:""GO:0030623""(U5 snRNA binding)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071006""(U2-type catalytic step 1 spliceosome)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097157""(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q6P2Q9|rcsb pdb:3E9L|rcsb pdb:3ENB|rcsb pdb:3JCR|rcsb pdb:3LRU|rcsb pdb:4JK7|rcsb pdb:4JK8|rcsb pdb:4JK9|rcsb pdb:4JKA|rcsb pdb:4JKB|rcsb pdb:4JKC|rcsb pdb:4JKD|rcsb pdb:4JKE|rcsb pdb:4JKF|rcsb pdb:4JKG|rcsb pdb:4JKH|rcsb pdb:4KIT|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|rcsb pdb:7OS2|rcsb pdb:7PJH|rcsb pdb:7PX3|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8BC8|rcsb pdb:8BC9|rcsb pdb:8BCA|rcsb pdb:8BCB|rcsb pdb:8BCC|rcsb pdb:8BCD|rcsb pdb:8BCE|rcsb pdb:8BCF|rcsb pdb:8BCG|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8Q7N|rcsb pdb:8Q7Q|rcsb pdb:8Q7V|rcsb pdb:8Q7W|rcsb pdb:8Q7X|rcsb pdb:8Q91|rcsb pdb:8QO9|rcsb pdb:8QOZ|rcsb pdb:8QP8|rcsb pdb:8QP9|rcsb pdb:8QPA|rcsb pdb:8QPB|rcsb pdb:8QPE|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RC0|rcsb pdb:8RM5|rcsb pdb:8RO2|rcsb pdb:8Y6O|rcsb pdb:9FMD|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_006436.3|dip:DIP-29614N|efo:""Orphanet:528084""|efo:""Orphanet:791""|panther:PTHR11140(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:1htJOEwkQpME5HLtvSLlZmF2H0s632	rogid:I0ot8b3pvieXRI66omFm145sGVA9606	intact-crc:D057F8A591519A85|rigid:ukUDlMVxFGQ2l58fAccoACfMTiQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAA1	uniprotkb:Q13523	intact:EBI-2860122|uniprotkb:Q74RC5|uniprotkb:Q8D1L7|uniprotkb:Q0WAA3	intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194.6|ensembl:ENSP00000433547.1	psi-mi:btub_yerpe(display_long)|uniprotkb:btuB(gene name)|psi-mi:btuB(display_short)|uniprotkb:Cobalamin receptor(gene name synonym)|uniprotkb:Outer membrane cobalamin translocator(gene name synonym)|uniprotkb:YPO3910(locus name)|uniprotkb:y0325(locus name)|uniprotkb:YP_3138(locus name)	psi-mi:prp4k_human(display_long)|uniprotkb:PRP4K(gene name)|psi-mi:PRP4K(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4B(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRPF4K(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860612|imex:IM-13779-6538	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010101(TonB-dependent vitamin B12 receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR039426|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0015420""(ABC-type vitamin B12 transporter activity)|go:""GO:0015889""(cobalamin transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0046930""(pore complex)|interpro:IPR036942|interpro:IPR037066|refseq:WP_002228170.1|panther:PTHR30069(orthology-group)"	"refseq:NP_003904.3|ensembl:ENSG00000112739.17(gene)|ensembl:ENST00000337659.11(transcript)|ensembl:ENST00000480058.5(transcript)|go:""GO:0000244""(spliceosomal tri-snRNP complex assembly)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000776""(kinetochore)|go:""GO:0003723""(RNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016607""(nuclear speck)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045292""(mRNA cis splicing, via spliceosome)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090266""(regulation of mitotic cell cycle spindle assembly checkpoint)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|interpro:IPR050494|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8QXD|rcsb pdb:8R08|rcsb pdb:8R0A|rcsb pdb:8Y6O|reactome:R-HSA-72163|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1|panther:PTHR24056(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DOy5Ti+yMtG0ogW80Av35K2fKW0632	rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606	intact-crc:36A7A1CA8181FB32|rigid:AT9FR9l0oULjL/1hvRlng7j+EoU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1C5	uniprotkb:O94903	intact:EBI-2842614	intact:EBI-2860631|uniprotkb:Q6FI94|ensembl:ENSP00000333551.3	psi-mi:q8d1c5_yerpe(display_long)|uniprotkb:phnI(gene name)|psi-mi:phnI(display_short)|uniprotkb:y0727(locus name)	psi-mi:plphp_human(display_long)|uniprotkb:PLPBP(gene name)|psi-mi:PLPBP(display_short)|uniprotkb:PROSC(gene name synonym)|uniprotkb:Proline synthase co-transcribed bacterial homolog protein(gene name synonym)|uniprotkb:Pyridoxal phosphate-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860636|imex:IM-13779-6537	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008773(Phosphonate metabolism)|go:""GO:0019634""(organic phosphonate metabolic process)"	"ensembl:ENSG00000147471.12(gene)|ensembl:ENST00000328195.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR011078(Predicted pyridoxal phosphate-dependent enzyme, YBL036C type)|interpro:IPR029066|mint:O94903|refseq:NP_009129.1|efo:""Orphanet:3006""|panther:PTHR10146(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AbNsdhrfAkwhBQT3IgXGyOmugPY632	rogid:xrOEPMjG0y+otG21Al6Q0UuQcEY9606	intact-crc:4CAB9DD743592EAE|rigid:P90kNvf79vxF/ux45R87JCB5VoM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13162	uniprotkb:A0A5P8YEC7	intact:EBI-2211957|ensembl:ENSP00000368646.4|uniprotkb:Q6FHT3	intact:EBI-2855406	psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)	psi-mi:a0a5p8yec7_yerpe(display_long)|uniprotkb:putA(gene name)|psi-mi:putA(display_short)|uniprotkb:y2455(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860669|imex:IM-13779-6543	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000123131.13(gene)|ensembl:ENST00000379341.9(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007252""(I-kappaB phosphorylation)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0008584""(male gonad development)|go:""GO:0022417""(obsolete protein maturation by protein folding)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140313""(molecular sequestering activity)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000255""(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|interpro:IPR050217|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|rcsb pdb:8EKW|rcsb pdb:8EKY|reactome:R-HSA-6798695|refseq:NP_006397.1|panther:PTHR10681(orthology-group)"	"interpro:IPR002872(Proline dehydrogenase)|interpro:IPR005933(Delta-1-pyrroline-5-carboxylate dehydrogenase 3)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR024082|interpro:IPR024089|interpro:IPR024090|interpro:IPR025703|interpro:IPR029041|interpro:IPR029510|interpro:IPR041349|interpro:IPR050485|uniprotkb:A0A6B3T0Q3(uniprot-removed-ac)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003842""(1-pyrroline-5-carboxylate dehydrogenase activity)|go:""GO:0004657""(proline dehydrogenase activity)|go:""GO:0006561""(proline biosynthetic process)|go:""GO:0010133""(proline catabolic process to glutamate)|go:""GO:0043565""(sequence-specific DNA binding)|interpro:IPR048798|refseq:WP_002224448.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606	rogid:74tf8h9/P3GoEJSTSbP1lNh73KI632	intact-crc:1E214D70B28148B0|rigid:nRSc5LUbVzzjKpD9IaaTc26jX2k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8Z9Z1	uniprotkb:P30048	intact:EBI-2860676|uniprotkb:Q7CFR0|uniprotkb:Q0W9Y7|uniprotkb:Q74QR2	intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|ensembl:ENSP00000298510.2|uniprotkb:E9PH29	psi-mi:xyla_yerpe(display_long)|uniprotkb:xylA(gene name)|psi-mi:xylA(display_short)|uniprotkb:YPO4038(locus name)|uniprotkb:y4057(locus name)|uniprotkb:YP_3400(locus name)	psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860683|imex:IM-13779-6541	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013452(Xylose isomerase, bacterial type)|interpro:IPR001998(Xylose isomerase)|refseq:WP_002209593.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009045""(xylose isomerase activity)|go:""GO:0042843""(D-xylose catabolic process)|interpro:IPR036237|refseq:YP_002348901.1|panther:PTHR32176(orthology-group)"	"refseq:NP_006784.1|ensembl:ENSG00000165672.7(gene)|ensembl:ENST00000298510.4(transcript)|go:""GO:0001893""(maternal placenta development)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0018171""(peptidyl-cysteine oxidation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033673""(negative regulation of kinase activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0102039""(NADH-dependent peroxiredoxin activity)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|interpro:IPR050217|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|refseq:NP_001289201.1|dip:DIP-33600N|panther:PTHR10681(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:DDYiFXiPcm9LEaNOw8cvbDYTX8U632	rogid:+J/zV8u0jGCSzTGXafxgecTv/149606	intact-crc:85416FB53E55740B|rigid:Heubo/kKTaliMaBlAQDaTumoWBw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WJW6	uniprotkb:P30048	intact:EBI-2860690|uniprotkb:Q74XD4|uniprotkb:Q7CKN1|uniprotkb:A0A3N4AXG1|uniprotkb:A0A0H2W329	intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|ensembl:ENSP00000298510.2|uniprotkb:E9PH29	psi-mi:q0wjw6_yerpe(display_long)|uniprotkb:b4079(gene name)|psi-mi:b4079(display_short)|uniprotkb:fdhF(gene name synonym)|uniprotkb:YPO0344(locus name)	psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860695|imex:IM-13779-6542	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006478(Formate dehydrogenase, alpha subunit)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR027467|refseq:WP_002209120.1|interpro:IPR050123|go:""GO:0008863""(""formate dehydrogenase (NAD+) activity"")|go:""GO:0015942""(formate metabolic process)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:1990204""(oxidoreductase complex)|interpro:IPR041924|refseq:YP_002345422.1"	"refseq:NP_006784.1|ensembl:ENSG00000165672.7(gene)|ensembl:ENST00000298510.4(transcript)|go:""GO:0001893""(maternal placenta development)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0018171""(peptidyl-cysteine oxidation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033673""(negative regulation of kinase activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0102039""(NADH-dependent peroxiredoxin activity)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|interpro:IPR050217|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|refseq:NP_001289201.1|dip:DIP-33600N|panther:PTHR10681(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:k6dXgc/93CsEB3BuTI7fZvAR+eo632	rogid:+J/zV8u0jGCSzTGXafxgecTv/149606	intact-crc:00636963B7C0528A|rigid:pHMIfzdBxX7TkdOwgY2FDBS7JWc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VBG2	uniprotkb:Q8TCU6	intact:EBI-2849663	intact:EBI-1046542|uniprotkb:E1P5X9|uniprotkb:Q5JS95|uniprotkb:Q5JS96|uniprotkb:Q69YL2|uniprotkb:Q7Z2L9|uniprotkb:Q9BQH0|uniprotkb:Q9BX55|uniprotkb:Q9H4Q6|uniprotkb:Q9P2D2|uniprotkb:Q9UGQ4|ensembl:ENSP00000361009.3	psi-mi:a0a6b3vbg2_yerpe(display_long)|uniprotkb:yapB(gene name)|psi-mi:yapB(display_short)|uniprotkb:y1345(locus name)	psi-mi:prex1_human(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860662|imex:IM-13779-6540	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|uniprotkb:A0A6B3T6Y5(uniprot-removed-ac)|go:""GO:0019867""(outer membrane)|interpro:IPR051551"	"refseq:NP_065871.2|ensembl:ENSG00000124126.14(gene)|ensembl:ENST00000371941.4(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006801""(superoxide metabolic process)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0023051""(regulation of signaling)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030426""(growth cone)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042119""(neutrophil activation)|go:""GO:0043198""(dendritic shaft)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050773""(regulation of dendrite development)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR036388|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036390|interpro:IPR051832|interpro:IPR055251|mint:Q8TCU6|rcsb pdb:3QIK|rcsb pdb:4YON|rcsb pdb:5D27|rcsb pdb:5D3V|rcsb pdb:5D3W|rcsb pdb:5D3X|rcsb pdb:5D3Y|rcsb pdb:5FI0|rcsb pdb:5FI1|rcsb pdb:6PCV|rcsb pdb:6VSK|rcsb pdb:7RX9|rcsb pdb:8TUA|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|dip:DIP-46975N|panther:PTHR22829(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jNPx4rqCv9bEZelj7jbp42kW+NY632	rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606	intact-crc:3E4464B587D2219A|rigid:Esg1hYoHk7M6QRgu3EIaYRk0J2s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P07737	uniprotkb:A0A5P8YDU7	intact:EBI-713780|uniprotkb:Q53Y44|ensembl:ENSP00000225655.5	intact:EBI-2846054|uniprotkb:Q74VN3|uniprotkb:A0A0H2W386|uniprotkb:Q7CHG5|uniprotkb:A0A2U2H0F8|uniprotkb:A0A384KD64	psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym)	psi-mi:a0a5p8ydu7_yerpe(display_long)|uniprotkb:YPO1330(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860655|imex:IM-13779-6544	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108518.8(gene)|ensembl:ENST00000225655.6(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0003785""(actin monomer binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030837""(negative regulation of actin filament polymerization)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032232""(negative regulation of actin filament bundle assembly)|go:""GO:0032233""(positive regulation of actin filament bundle assembly)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050821""(protein stabilization)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0060074""(synapse maturation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0072562""(blood microparticle)|go:""GO:0098885""(modification of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900029""(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|interpro:IPR048278|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|rcsb pdb:7P1H|rcsb pdb:8BJH|rcsb pdb:8BJI|rcsb pdb:8BJJ|rcsb pdb:8BR0|rcsb pdb:8RTY|rcsb pdb:9AZP|reactome:R-HSA-114608|reactome:R-HSA-376176|reactome:R-HSA-4086400|reactome:R-HSA-5663220|refseq:NP_005013.1|dip:DIP-30N|efo:""Orphanet:803""|panther:PTHR13936(orthology-group)"	interpro:IPR019660|refseq:WP_002208763.1|refseq:YP_002346355.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606	rogid:Ue8A5mhje57pQqJVwmBF+iP8ruI632	intact-crc:8487946B8FC3744E|rigid:ncwIi1KUoyT3zN553/zbHBs514E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30048	uniprotkb:Q7CHU1	intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|ensembl:ENSP00000298510.2|uniprotkb:E9PH29	intact:EBI-2841165|uniprotkb:Q74V60	psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	psi-mi:mtfa_yerpe(display_long)|uniprotkb:mtfA(gene name)|psi-mi:mtfA(display_short)|uniprotkb:Probable zinc metallopeptidase MtfA(gene name synonym)|uniprotkb:YPO1732(locus name)|uniprotkb:YP_1472(locus name)|uniprotkb:y2576(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860716|imex:IM-13779-6546	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006784.1|ensembl:ENSG00000165672.7(gene)|ensembl:ENST00000298510.4(transcript)|go:""GO:0001893""(maternal placenta development)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0018171""(peptidyl-cysteine oxidation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033673""(negative regulation of kinase activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0102039""(NADH-dependent peroxiredoxin activity)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|interpro:IPR050217|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|refseq:NP_001289201.1|dip:DIP-33600N|panther:PTHR10681(orthology-group)"	"refseq:YP_002346732.1|interpro:IPR024079|interpro:IPR010384(Protein of unknown function DUF980)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|refseq:WP_002211042.1|interpro:IPR042252|panther:PTHR30164(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:+J/zV8u0jGCSzTGXafxgecTv/149606	rogid:3PKDmcLXdDD+p8B4M6novftNc7A632	intact-crc:83031BA5E15617A7|rigid:ZdREsml3LWLOad5ugLUAWTYySC4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P68587	uniprotkb:Q06830	intact:EBI-2844901|uniprotkb:P40295	intact:EBI-353193|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8|ensembl:ENSP00000262746.1|ensembl:ENSP00000361152.5|ensembl:ENSP00000389047.2|ensembl:ENSP00000407034.2|ensembl:ENSP00000503140.1	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860730|imex:IM-13779-6549	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|ensembl:ENSG00000117450.15(gene)|ensembl:ENST00000262746.5(transcript)|ensembl:ENST00000319248.13(transcript)|ensembl:ENST00000424390.2(transcript)|ensembl:ENST00000447184.6(transcript)|ensembl:ENST00000676549.1(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0003723""(RNA binding)|go:""GO:0004601""(peroxidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0019430""(removal of superoxide radicals)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0034101""(erythrocyte homeostasis)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042470""(melanosome)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045321""(leukocyte activation)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1901222""(regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|interpro:IPR050217|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|rcsb pdb:7LJ1|rcsb pdb:7WET|rcsb pdb:7WEU|rcsb pdb:8X71|rcsb pdb:8X73|rcsb pdb:8Z54|rcsb pdb:8Z55|rcsb pdb:8Z56|rcsb pdb:8Z57|rcsb pdb:8Z58|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|reactome:R-HSA-9818027|dip:DIP-33152N|panther:PTHR10681(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	intact-crc:BA2C3304D462CD3F|rigid:sTAZtXfmliqZlRKmmBxDjPXj7Wc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30048	uniprotkb:A0A0H2W240	intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|ensembl:ENSP00000298510.2|uniprotkb:E9PH29	intact:EBI-2850287|uniprotkb:Q74VW1|uniprotkb:Q7CJX7|uniprotkb:Q0WD93	psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	psi-mi:a0a0h2w240_yerpe(display_long)|uniprotkb:YPO2804(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860702|imex:IM-13779-6545	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006784.1|ensembl:ENSG00000165672.7(gene)|ensembl:ENST00000298510.4(transcript)|go:""GO:0001893""(maternal placenta development)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0018171""(peptidyl-cysteine oxidation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033673""(negative regulation of kinase activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0102039""(NADH-dependent peroxiredoxin activity)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|interpro:IPR050217|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|refseq:NP_001289201.1|dip:DIP-33600N|panther:PTHR10681(orthology-group)"	refseq:WP_002209759.1|refseq:YP_002347745.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:+J/zV8u0jGCSzTGXafxgecTv/149606	rogid:JhYA2WkP/pLAsCxyNh5bCfVn+IA632	intact-crc:E6BDDF3B97222706|rigid:smQmeFKrfPFNs0XancypdgJozoI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30048	uniprotkb:Q8ZI61	intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|ensembl:ENSP00000298510.2|uniprotkb:E9PH29	intact:EBI-2856600|uniprotkb:Q0WJ17|uniprotkb:Q8CZR9|uniprotkb:Q74RQ4	psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	"psi-mi:glne_yerpe(display_long)|uniprotkb:glnE(gene name)|psi-mi:glnE(display_short)|uniprotkb:""ATP:glutamine synthetase adenylyltransferase""(gene name synonym)|uniprotkb:ATase(gene name synonym)|uniprotkb:YPO0653(locus name)|uniprotkb:YP_2968(locus name)|uniprotkb:y3525(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860723|imex:IM-13779-6547	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006784.1|ensembl:ENSG00000165672.7(gene)|ensembl:ENST00000298510.4(transcript)|go:""GO:0001893""(maternal placenta development)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0018171""(peptidyl-cysteine oxidation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033673""(negative regulation of kinase activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0102039""(NADH-dependent peroxiredoxin activity)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|interpro:IPR050217|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|refseq:NP_001289201.1|dip:DIP-33600N|panther:PTHR10681(orthology-group)"	"interpro:IPR023057|interpro:IPR005190(Glutamate-ammonia ligase adenylyltransferase)|interpro:IPR013546(GlnD PII-uridylyltransferase)|refseq:WP_002212194.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000820""(regulation of glutamine family amino acid metabolic process)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008882""([glutamate-ammonia-ligase] adenylyltransferase activity)|go:""GO:0047388""([glutamine synthetase]-adenylyl-L-tyrosine phosphorylase activity)|interpro:IPR043519|refseq:YP_002345721.1|panther:PTHR30621(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:+J/zV8u0jGCSzTGXafxgecTv/149606	rogid:RoEcJZfF/CSIgmtP9TYrZ6mEC70632	intact-crc:FDC63FB53E41CD23|rigid:dHVjZE6uJgEnw95lsOEbDQMZ7VA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30048	uniprotkb:A0A2U2H272	intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|ensembl:ENSP00000298510.2|uniprotkb:E9PH29	intact:EBI-2846184|uniprotkb:Q74Y19|uniprotkb:Q0WKE0|uniprotkb:Q7CFV9|uniprotkb:A0A384LDU9	psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	psi-mi:a0a2u2h272_yerpe(display_long)|uniprotkb:codA(gene name)|psi-mi:codA(display_short)|uniprotkb:YPO0162(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860709|imex:IM-13779-6548	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006784.1|ensembl:ENSG00000165672.7(gene)|ensembl:ENST00000298510.4(transcript)|go:""GO:0001893""(maternal placenta development)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0018171""(peptidyl-cysteine oxidation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033673""(negative regulation of kinase activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0102039""(NADH-dependent peroxiredoxin activity)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|interpro:IPR050217|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|refseq:NP_001289201.1|dip:DIP-33600N|panther:PTHR10681(orthology-group)"	"interpro:IPR013108(Amidohydrolase 3)|interpro:IPR011059(Metal-dependent hydrolase, composite)|go:""GO:0004131""(cytosine deaminase activity)|go:""GO:0006209""(cytosine catabolic process)|go:""GO:0035888""(isoguanine deaminase activity)|interpro:IPR032466|refseq:YP_002345248.1|interpro:IPR052349|panther:PTHR32027(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:+J/zV8u0jGCSzTGXafxgecTv/149606	rogid:sKugK78/Nviq8A3SGcJ/uWrDZto632	intact-crc:53A4864D86483CFE|rigid:EbNIqhFDYnfNykgE2M1qbwkf9FQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5VTL8	uniprotkb:A0A3N4BNK4	intact:EBI-1045334|uniprotkb:Q05DD6|uniprotkb:Q32Q58|uniprotkb:Q5VTL9|uniprotkb:Q6PK39|uniprotkb:Q7Z6E2|uniprotkb:Q86WF3|uniprotkb:Q8IWG9|uniprotkb:Q9NW40|ensembl:ENSP00000359042.4	intact:EBI-2855448|uniprotkb:A0A380PK27|uniprotkb:Q0WDQ1|uniprotkb:Q7CJU1	psi-mi:pr38b_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-27(gene name synonym)|uniprotkb:PRPF38B(gene name)|psi-mi:PRPF38B(display_short)	psi-mi:a0a3n4bnk4_yerpe(display_long)|uniprotkb:ybfM(gene name)|psi-mi:ybfM(display_short)|uniprotkb:YPO2631(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860770|imex:IM-13779-6551	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060531.2|ensembl:ENSG00000134186.12(gene)|ensembl:ENST00000370025.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0071011""(precatalytic spliceosome)|interpro:IPR005037(PRP38)|mint:Q5VTL8|panther:PTHR23142(orthology-group)"	"interpro:IPR005318(Outer membrane porin, bacterial)|refseq:WP_002210355.1|go:""GO:0016020""(membrane)|interpro:IPR023614|refseq:YP_002347587.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AWwws/iWEHoeyV7o3bgLKBQKgQ49606	rogid:kQOm62Hk7MNtNLAcnBC4bzThrBs632	intact-crc:40F3AE446AAA6265|rigid:T+prPFeGGVr6jOyk2e4zYI4M3CY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PMQ0	uniprotkb:O75400	intact:EBI-2840516|uniprotkb:Q74WF1|uniprotkb:A0A0H2W3X0|uniprotkb:Q7CH96	intact:EBI-473291|uniprotkb:O43856|uniprotkb:O75404|uniprotkb:Q8TBQ1|uniprotkb:Q9H782|uniprotkb:Q9NWU9|uniprotkb:Q9P0Q2|uniprotkb:Q9Y5A8|ensembl:ENSP00000512591.1	psi-mi:a0a380pmq0_yerpe(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:hisW(gene name synonym)|uniprotkb:nalA(gene name synonym)|uniprotkb:parD(gene name synonym)|uniprotkb:YPO1216(locus name)	psi-mi:pr40a_human(display_long)|uniprotkb:Formin-binding protein 3(gene name synonym)|uniprotkb:Formin-binding protein 11(gene name synonym)|uniprotkb:Huntingtin-interacting protein A(gene name synonym)|uniprotkb:Huntingtin yeast partner A(gene name synonym)|uniprotkb:Fas ligand-associated factor 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-6(gene name synonym)|uniprotkb:HSPC225(orf name)|uniprotkb:HYPA(gene name synonym)|uniprotkb:PRPF40A(gene name)|psi-mi:PRPF40A(display_short)|uniprotkb:FLAF1(gene name synonym)|uniprotkb:FBP11(gene name synonym)|uniprotkb:FNBP3(gene name synonym)|uniprotkb:HIP10(gene name synonym)|uniprotkb:Huntingtin-interacting protein 10(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860763|imex:IM-13779-6553	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006265""(DNA topological change)|go:""GO:0009330""(""DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex"")|go:""GO:0034335""(DNA negative supercoiling activity)|refseq:WP_002210821.1|refseq:YP_002346250.1|interpro:IPR035516|interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR050220|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|panther:PTHR43493(orthology-group)"	"refseq:NP_060362.3|panther:PTHR11864(orthology-group)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002713(FF)|ensembl:ENSG00000196504.21(gene)|ensembl:ENST00000696381.1(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005685""(U1 snRNP)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0016607""(nuclear speck)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0045292""(mRNA cis splicing, via spliceosome)|go:""GO:0051301""(cell division)|go:""GO:0071004""(U2-type prespliceosome)|interpro:IPR036020|interpro:IPR036517|interpro:IPR039726|mint:O75400|rcsb pdb:1UZC|rcsb pdb:1YWI|rcsb pdb:1YWJ|rcsb pdb:1ZR7|rcsb pdb:2CQN|rcsb pdb:2DYF|rcsb pdb:2KZG|rcsb pdb:2L5F|rcsb pdb:2L9V|rcsb pdb:2LKS|rcsb pdb:8PXW|rcsb pdb:8PXX|reactome:R-HSA-72163"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:14H4sDitlL6oLmBRsSQONtZJ468632	rogid:XgnBshjHK5u08HROtUS9Zr2Ot809606	intact-crc:2E9EE968B2F1B9E5|rigid:ixdQcFdXZBlzuhTUUOmCOwhx34A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q65AQ0	uniprotkb:Q5VTL8	intact:EBI-2840948|uniprotkb:Q7ARF1|uniprotkb:O68736|uniprotkb:Q74YP7|uniprotkb:A0A1U8QHE0|uniprotkb:A0A384L0B5|uniprotkb:A0A380PGV8	intact:EBI-1045334|uniprotkb:Q05DD6|uniprotkb:Q32Q58|uniprotkb:Q5VTL9|uniprotkb:Q6PK39|uniprotkb:Q7Z6E2|uniprotkb:Q86WF3|uniprotkb:Q8IWG9|uniprotkb:Q9NW40|ensembl:ENSP00000359042.4	psi-mi:q65aq0_yerpe(display_long)|uniprotkb:YPMT1.20c(locus name)	psi-mi:pr38b_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-27(gene name synonym)|uniprotkb:PRPF38B(gene name)|psi-mi:PRPF38B(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860777|imex:IM-13779-6552	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|refseq:NP_395356.1|refseq:YP_093897.1|refseq:WP_002211783.1	"refseq:NP_060531.2|ensembl:ENSG00000134186.12(gene)|ensembl:ENST00000370025.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0071011""(precatalytic spliceosome)|interpro:IPR005037(PRP38)|mint:Q5VTL8|panther:PTHR23142(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ddNAMtYP5UYjatxR1iFv4p5Pwns632	rogid:AWwws/iWEHoeyV7o3bgLKBQKgQ49606	intact-crc:50CAB5B965CB7228|rigid:AQOOriPgypTVp8XWouV+dHahc9Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:O75915	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258.3	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860749|imex:IM-13779-6550	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:NP_006398.1|ensembl:ENSG00000144746.7(gene)|ensembl:ENST00000273258.4(transcript)|go:""GO:0002037""(negative regulation of L-glutamate import across plasma membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0007611""(learning or memory)|go:""GO:0008631""(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:""GO:0010917""(negative regulation of mitochondrial membrane potential)|go:""GO:0015031""(protein transport)|go:""GO:0015813""(L-glutamate transmembrane transport)|go:""GO:0016020""(membrane)|go:""GO:0032874""(positive regulation of stress-activated MAPK cascade)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0051051""(negative regulation of transport)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098712""(L-glutamate import across plasma membrane)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|panther:PTHR12859(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606	intact-crc:91DE056E5BB4841D|rigid:/6l2ihmVYDDLr+S4+LU6ohvAwBU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96QH2	uniprotkb:Q8D041	intact:EBI-2860740|uniprotkb:Q8N6W7|intact:EBI-11995316|ensembl:ENSP00000408342.2	intact:EBI-2851114|uniprotkb:Q74VR7	psi-mi:pram_human(display_long)|uniprotkb:PRAM1(gene name)|psi-mi:PRAM1(display_short)	psi-mi:q8d041_yerpe(display_long)|uniprotkb:clpA(gene name)|psi-mi:clpA(display_short)|uniprotkb:clpA1(gene name synonym)|uniprotkb:YP_1225(locus name)|uniprotkb:y2809(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860737|imex:IM-13779-6554	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115528.4|interpro:IPR029294|interpro:IPR036028|interpro:IPR043443|ensembl:ENSG00000133246.12(gene)|ensembl:ENST00000423345.5(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008289""(lipid binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0043313""(regulation of neutrophil degranulation)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|panther:PTHR16830(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR013461(ATP-dependent Clp protease ATP-binding subunit clpA)|interpro:IPR027417|interpro:IPR028299|go:""GO:0005524""(ATP binding)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0043335""(protein unfolding)|interpro:IPR036628|interpro:IPR041546|interpro:IPR050130"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ndKSfxjK+LbX4/+2cSRfQATKTM89606	rogid:s5Ofou/48VE84z5dH0ElXjvQns8632	intact-crc:A7635C2E6A8A4099|rigid:iiZ8d9ZpDOa8NDHHprT2MzZ81UQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5VV67	uniprotkb:A0A0H2W2N9	intact:EBI-1045850|uniprotkb:Q5VV66|uniprotkb:Q6P3U5|uniprotkb:Q6P3W1|uniprotkb:Q76N31|uniprotkb:Q9BUJ3|uniprotkb:Q9BZE5|uniprotkb:Q9Y4E0|intact:EBI-28968769|ensembl:ENSP00000278070.2	intact:EBI-2840467|uniprotkb:Q74XT4|uniprotkb:Q0WBR4|uniprotkb:A0A384L498|uniprotkb:Q7CKD3|uniprotkb:A0A3N4B9W7	psi-mi:pprc1_human(display_long)|uniprotkb:PGC-1-related coactivator(gene name synonym)|uniprotkb:PPRC1(gene name)|psi-mi:PPRC1(display_short)|uniprotkb:KIAA0595(gene name synonym)	psi-mi:a0a0h2w2n9_yerpe(display_long)|uniprotkb:degP(gene name)|psi-mi:degP(display_short)|uniprotkb:gsrA(gene name synonym)|uniprotkb:htrA(gene name synonym)|uniprotkb:ptd(gene name synonym)|uniprotkb:YPO3382(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860791|imex:IM-13779-6558	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055877.3|refseq:NP_001275656.1|refseq:NP_001275657.1|mint:Q5VV67|ensembl:ENSG00000148840.11(gene)|ensembl:ENST00000278070.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0097009""(energy homeostasis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034834|interpro:IPR035979|reactome:R-HSA-2151201|panther:PTHR15528(orthology-group)"	"interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:WP_002209370.1|refseq:YP_002348274.1|interpro:IPR036034"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CzoJyQC7ZylKapYmIL3Ik5IxhBk9606	rogid:wh5TqHAdstARdvvFDyS2kqzSnxY632	intact-crc:39B53E7B0B175B78|rigid:QD+FFuImA5fo1H+ztFpgfabX6Os	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96BP3	uniprotkb:Q8ZCQ2	intact:EBI-2827139|uniprotkb:Q15002|uniprotkb:Q7KZ89|uniprotkb:B4DWR9|ensembl:ENSP00000261308.4	intact:EBI-2850142|uniprotkb:Q0WCY7	psi-mi:ppwd1_human(display_long)|uniprotkb:PPWD1(gene name)|psi-mi:PPWD1(display_short)|uniprotkb:KIAA0073(gene name synonym)|uniprotkb:Spliceosome-associated cyclophilin(gene name synonym)	psi-mi:pur4_yerpe(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:YPO2921(locus name)|uniprotkb:YP_2536(locus name)|uniprotkb:y1309(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860784|imex:IM-13779-6555	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056157.1|refseq:NP_001265855.1|refseq:NP_001265856.1|refseq:NP_001265858.1|ensembl:ENSG00000113593.12(gene)|ensembl:ENST00000261308.10(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006457""(protein folding)|go:""GO:0016604""(nuclear body)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR029000|interpro:IPR036322|interpro:IPR044666|mint:Q96BP3|rcsb pdb:2A2N|rcsb pdb:5YZG|rcsb pdb:7A5P|rcsb pdb:8I0W|rcsb pdb:9FMD|reactome:R-HSA-72163|panther:PTHR45625(orthology-group)"	"interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR029062|refseq:WP_002211561.1|interpro:IPR040707|go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609|refseq:YP_002347851.1|panther:PTHR10099(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vM2ElmgCNRyiax53U2M7JgBkbfU9606	rogid:8JTbD5hWDWC5PK7sHtiOwqqdyHs632	intact-crc:06AA7BE899A33892|rigid:AIoQoEVQRZjKhTJY9mooSp6l9Wo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17778	uniprotkb:Q13427	intact:EBI-2842665|uniprotkb:O68701	intact:EBI-396072|uniprotkb:O00706|uniprotkb:Q96DG9|uniprotkb:Q53R40|uniprotkb:Q53SN4|uniprotkb:D3DPC5|uniprotkb:D3DPC6|ensembl:ENSP00000260970.3|ensembl:ENSP00000407083.2|ensembl:ENSP00000408683.2|ensembl:ENSP00000502997.1|ensembl:ENSP00000503136.1|ensembl:ENSP00000503525.1	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	psi-mi:ppig_human(display_long)|uniprotkb:PPIG(gene name)|psi-mi:PPIG(display_short)|uniprotkb:Cyclophilin G(gene name synonym)|uniprotkb:Clk-associating RS-cyclophilin(gene name synonym)|uniprotkb:CASP10(gene name synonym)|uniprotkb:Rotamase G(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860805|imex:IM-13779-6557	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"refseq:NP_004783.2|refseq:XP_005247023.1|refseq:XP_005247024.1|ensembl:ENSG00000138398.17(gene)|ensembl:ENST00000260970.8(transcript)|ensembl:ENST00000433207.6(transcript)|ensembl:ENST00000448752.7(transcript)|ensembl:ENST00000676756.1(transcript)|ensembl:ENST00000678499.1(transcript)|ensembl:ENST00000679107.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0008380""(RNA splicing)|go:""GO:0016018""(cyclosporin A binding)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:Q13427|rcsb pdb:2GW2|rcsb pdb:2WFI|rcsb pdb:2WFJ|rcsb pdb:5YZG|reactome:R-HSA-72163|reactome:R-HSA-9692916"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	rogid:gp1Pqv5G8E+PrPmp+BtUSSIkD/89606	intact-crc:C3E3795C36BE3AF4|rigid:0x5hUb6XVBN2LUAbvjf23vA7YZY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P23284	uniprotkb:Q8D126	intact:EBI-359252|uniprotkb:Q9BVK5|uniprotkb:A8K534|uniprotkb:Q6IBH5|ensembl:ENSP00000300026.4	intact:EBI-2860812|uniprotkb:Q74W08	psi-mi:ppib_human(display_long)|uniprotkb:PPIB(gene name)|psi-mi:PPIB(display_short)|uniprotkb:CYPB(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Rotamase B(gene name synonym)	psi-mi:q8d126_yerpe(display_long)|uniprotkb:tar2(gene name)|psi-mi:tar2(display_short)|uniprotkb:YP_1102(locus name)|uniprotkb:y1185(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860817|imex:IM-13779-6559	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:216804""|efo:""Orphanet:216812""|efo:""Orphanet:216820""|ensembl:ENSG00000166794.7(gene)|ensembl:ENST00000300026.4(transcript)|go:""GO:0000413""(protein peptidyl-prolyl isomerization)|go:""GO:0003723""(RNA binding)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0016018""(cyclosporin A binding)|go:""GO:0016020""(membrane)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0040018""(positive regulation of multicellular organism growth)|go:""GO:0042470""(melanosome)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0060348""(bone development)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P23284|rcsb pdb:1CYN|rcsb pdb:3ICH|rcsb pdb:3ICI|rcsb pdb:8K0F|rcsb pdb:8K0I|rcsb pdb:8K0M|rcsb pdb:8K17|rcsb pdb:8KC9|reactome:R-HSA-1650814|reactome:R-HSA-9692916|refseq:NP_000933.1"	interpro:IPR009912(Protein of unknown function DUF1451)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h6nKaPUyEYUctYuu/3XfFhM4y9c9606	rogid:L/9Y//+aDHX/4sDv9Wnxer1NsdY632	intact-crc:0435E6DB3D20C30C|rigid:Vj63xPIz1jJj2grJalgIggXSWNU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZK5	uniprotkb:Q9H939	intact:EBI-2845872|uniprotkb:Q74QX9	intact:EBI-2609610|ensembl:ENSP00000387261.4	psi-mi:q8czk5_yerpe(display_long)|uniprotkb:fba(gene name)|psi-mi:fba(display_short)|uniprotkb:YP_3323(locus name)|uniprotkb:y3869(locus name)	psi-mi:ppip2_human(display_long)|uniprotkb:PSTPIP2(gene name)|psi-mi:PSTPIP2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860798|imex:IM-13779-6556	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000771(Ketose-bisphosphate aldolase, class-II)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016832""(aldehyde-lyase activity)|interpro:IPR050246"	"refseq:NP_077748.3|ensembl:ENSG00000152229.18(gene)|ensembl:ENST00000409746.5(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0051015""(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR027267|interpro:IPR031160|interpro:IPR042694|mint:Q9H939|panther:PTHR23065(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:F4QkMnJWZdUUOo6ENRO8BbcEL+I632	rogid:ghqpcq5SdMjxt7NE9Yc7n6YiexA9606	intact-crc:9B38785F377F3C8F|rigid:1jgiJHFPQvHtgyWiWrGx9DAlkdE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380SBN9	uniprotkb:P05186	intact:EBI-2859606|uniprotkb:Q74VS2|uniprotkb:A0A384LDT6|uniprotkb:Q0WH40|uniprotkb:Q7CHI7	intact:EBI-1054354|uniprotkb:A1A4E7|uniprotkb:O75090|uniprotkb:Q2TAI7|uniprotkb:Q59EJ7|uniprotkb:Q5BKZ5|uniprotkb:Q5VTG5|uniprotkb:Q6NZI8|uniprotkb:Q8WU32|uniprotkb:Q9UBK0|uniprotkb:B7Z387|uniprotkb:B2RMP8|uniprotkb:B7Z4Y6|ensembl:ENSP00000363965.1|ensembl:ENSP00000363973.3	psi-mi:a0a380sbn9_yerpe(display_long)|uniprotkb:alsB(gene name)|psi-mi:alsB(display_short)|uniprotkb:ihb(gene name synonym)|uniprotkb:livR(gene name synonym)|uniprotkb:lrp(gene name synonym)|uniprotkb:oppI(gene name synonym)|uniprotkb:YPO1375(locus name)	psi-mi:ppbt_human(display_long)|uniprotkb:Alkaline phosphatase liver/bone/kidney isozyme(gene name synonym)|uniprotkb:ALPL(gene name)|psi-mi:ALPL(display_short)|uniprotkb:Phosphoamidase(gene name synonym)|uniprotkb:Phosphocreatine phosphatase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860857|imex:IM-13779-6562	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002346398.1|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR019888|interpro:IPR019887|interpro:IPR000485(Transcription regulator, AsnC/Lrp)|interpro:IPR011991(Winged helix repressor DNA-binding)|interpro:IPR019885|refseq:WP_002211340.1|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006524""(alanine catabolic process)|go:""GO:0043201""(response to L-leucine)|go:""GO:0043565""(sequence-specific DNA binding)|interpro:IPR036388|interpro:IPR036390|panther:PTHR30154(orthology-group)"	"efo:""Orphanet:247623""|efo:""Orphanet:247638""|efo:""Orphanet:247651""|efo:""Orphanet:247667""|efo:""Orphanet:247676""|efo:""Orphanet:247685""|ensembl:ENSG00000162551.14(gene)|ensembl:ENST00000374832.5(transcript)|ensembl:ENST00000374840.8(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001958""(endochondral ossification)|go:""GO:0003006""(developmental process involved in reproduction)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0004035""(alkaline phosphatase activity)|go:""GO:0004427""(inorganic diphosphate phosphatase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0016462""(pyrophosphatase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019725""(cellular homeostasis)|go:""GO:0030282""(bone mineralization)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031214""(biomineral tissue development)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032868""(response to insulin)|go:""GO:0033280""(response to vitamin D)|go:""GO:0033883""(pyridoxal phosphatase activity)|go:""GO:0034516""(response to vitamin B6)|go:""GO:0036005""(response to macrophage colony-stimulating factor)|go:""GO:0042822""(pyridoxal phosphate metabolic process)|go:""GO:0043262""(ADP phosphatase activity)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050187""(phosphoamidase activity)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0052732""(phosphoethanolamine phosphatase activity)|go:""GO:0055062""(phosphate ion homeostasis)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0071529""(cementum mineralization)|go:""GO:0098552""(side of membrane)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140651""(futile creatine cycle)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:0140928""(inhibition of non-skeletal tissue mineralization)|go:""GO:1904383""(response to sodium phosphate)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|mint:P05186|rcsb pdb:7YIV|rcsb pdb:7YIW|rcsb pdb:7YIX|reactome:R-HSA-163125|refseq:NP_000469.3|refseq:NP_001120973.2|refseq:NP_001170991.1|refseq:XP_005245875.1|refseq:XP_006710609.1|panther:PTHR11596(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UhsFhiqr8/nsqSc1PV5oRdAtSvs632	rogid:iO0/TZ5yjqLOEZWp673XGt02mnI9606	intact-crc:42A34C637C8DA73F|rigid:po+TDbhPlhdlY3M+TCaQliFdUts	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIL4	uniprotkb:P10619	intact:EBI-2852663|uniprotkb:Q0WJI3	intact:EBI-989654|uniprotkb:Q9BW68|uniprotkb:Q561W6|uniprotkb:Q5JZH1|uniprotkb:Q96KJ2|uniprotkb:Q9BR08|uniprotkb:B2R798|ensembl:ENSP00000191018.5|ensembl:ENSP00000361537.2|ensembl:ENSP00000475524.2|ensembl:ENSP00000493613.2	psi-mi:carb_yerpe(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:YPO0482(locus name)|uniprotkb:YP_3697(locus name)|uniprotkb:y3692(locus name)	psi-mi:ppgb_human(display_long)|uniprotkb:Cathepsin A(gene name synonym)|uniprotkb:Carboxypeptidase C(gene name synonym)|uniprotkb:Protective protein for beta-galactosidase(gene name synonym)|uniprotkb:CTSA(gene name)|psi-mi:CTSA(display_short)|uniprotkb:PPGB(gene name synonym)|uniprotkb:Carboxypeptidase L(gene name synonym)|uniprotkb:Protective protein cathepsin A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860838|imex:IM-13779-6563	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|refseq:WP_002210502.1|go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR033937|interpro:IPR036897|interpro:IPR036914|refseq:YP_002345555.1|panther:PTHR11405(orthology-group)"	"efo:""Orphanet:351""|efo:""Orphanet:575553""|ensembl:ENSG00000064601.21(gene)|ensembl:ENST00000191018.9(transcript)|ensembl:ENST00000372459.7(transcript)|ensembl:ENST00000607482.6(transcript)|ensembl:ENST00000646241.3(transcript)|go:""GO:0004180""(carboxypeptidase activity)|go:""GO:0004185""(serine-type carboxypeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006508""(proteolysis)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0016020""(membrane)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904714""(regulation of chaperone-mediated autophagy)|go:""GO:1904715""(negative regulation of chaperone-mediated autophagy)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|interpro:IPR033124|mint:P10619|rcsb pdb:1IVY|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BXN|rcsb pdb:4AZ0|rcsb pdb:4AZ3|rcsb pdb:4CI9|rcsb pdb:4CIA|rcsb pdb:4CIB|rcsb pdb:4MWS|rcsb pdb:4MWT|rcsb pdb:6WIA|reactome:R-HSA-2132295|reactome:R-HSA-4085001|reactome:R-HSA-4341670|reactome:R-HSA-6798695|reactome:R-HSA-9840310|refseq:NP_000299.2|refseq:NP_001121167.1|refseq:NP_001161066.1|panther:PTHR11802(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l/RzabCD1P/dEo/AmaYoXpYV1FY632	rogid:l/CZaKjZTuZu1ROoJJZVsxobYrQ9606	intact-crc:362BCB01235A39F3|rigid:8JeEf6KIexwIl2oC3jzxcmgir3c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CG77	uniprotkb:Q4J6C6	intact:EBI-2860845|uniprotkb:Q74Q13	intact:EBI-949331|uniprotkb:A7E2X6|uniprotkb:O43163|uniprotkb:Q4J6C3|uniprotkb:Q4J6C4|uniprotkb:Q4ZG39|uniprotkb:Q6ZMW7|uniprotkb:Q96DW7|uniprotkb:D6W5A3|ensembl:ENSP00000260648.6|ensembl:ENSP00000386509.1|ensembl:ENSP00000386543.1|ensembl:ENSP00000386909.1|ensembl:ENSP00000391456.1|ensembl:ENSP00000409480.1	psi-mi:nhaa_yerpe(display_long)|uniprotkb:nhaA(gene name)|psi-mi:nhaA(display_short)|uniprotkb:Sodium/proton antiporter NhaA(gene name synonym)|uniprotkb:YPO0470(locus name)|uniprotkb:YP_3710(locus name)|uniprotkb:y3704(locus name)	psi-mi:ppcel_human(display_long)|uniprotkb:KIAA0436(gene name synonym)|uniprotkb:Prolylendopeptidase-like(gene name synonym)|uniprotkb:PREPL(gene name)|psi-mi:PREPL(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860850|imex:IM-13779-6561	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023171|interpro:IPR004670(Na+/H+ antiporter NhaA)|refseq:WP_002220711.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006885""(regulation of pH)|go:""GO:0015385""(""sodium:proton antiporter activity"")|refseq:YP_002345542.1|panther:PTHR30341(orthology-group)"	"ensembl:ENSG00000138078.16(gene)|ensembl:ENST00000260648.10(transcript)|ensembl:ENST00000409272.5(transcript)|ensembl:ENST00000409936.5(transcript)|ensembl:ENST00000410081.5(transcript)|ensembl:ENST00000425263.5(transcript)|ensembl:ENST00000426481.5(transcript)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002470(Peptidase S9A, prolyl oligopeptidase)|interpro:IPR023302|interpro:IPR029058|interpro:IPR051543|mint:Q4J6C6|rcsb pdb:7OBM|rcsb pdb:8RFB|refseq:NP_001035844.1|refseq:NP_001035845.1|refseq:NP_001165074.1|refseq:NP_001165077.1|refseq:NP_001165084.1|refseq:NP_001165088.1|refseq:NP_006027.2|refseq:XP_011531500.1|refseq:XP_011531502.1|refseq:XP_011531504.1|refseq:XP_016860873.1|refseq:XP_016860874.1|efo:""Orphanet:163690""|efo:""Orphanet:163693""|efo:""Orphanet:238523""|efo:""Orphanet:369881""|panther:PTHR11757(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2jzd3JIvL38CrOPFxGfkKb82j14632	rogid:xn++9zR6AX/HzP4KzrriJR5IUTk9606	intact-crc:F7BC0FF0DC8B0114|rigid:41j/RkU44JjwRtKKMNUdoMQy9D4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NEY8	uniprotkb:Q8CZR5	intact:EBI-474076|uniprotkb:Q8TB09|uniprotkb:Q86YT2|uniprotkb:Q8IXN3|uniprotkb:Q96NB9|uniprotkb:Q9NXL4|uniprotkb:Q9P0P6|uniprotkb:Q9P0R9|uniprotkb:E9PAX8|ensembl:ENSP00000378935.2|ensembl:ENSP00000479913.1	intact:EBI-2839873	psi-mi:pphln_human(display_long)|uniprotkb:Gastric cancer antigen Ga50(gene name synonym)|uniprotkb:HSPC206(orf name)|uniprotkb:HSPC232(orf name)|uniprotkb:PPHLN1(gene name)|psi-mi:PPHLN1(display_short)|uniprotkb:CDC7 expression repressor(gene name synonym)	psi-mi:q8czr5_yerpe(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:y3537(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860824|imex:IM-13779-6564	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137259.1|refseq:NP_001137260.1|refseq:NP_057572.5|refseq:NP_958846.1|refseq:NP_958847.1|refseq:NP_958848.1|refseq:NP_958923.1|dip:DIP-49051N|ensembl:ENSG00000134283.18(gene)|ensembl:ENST00000395568.6(transcript)|ensembl:ENST00000610488.4(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0031424""(keratinization)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0097355""(protein localization to heterochromatin)|go:""GO:0140719""(constitutive heterochromatin formation)|interpro:IPR028851|mint:Q8NEY8|rcsb pdb:6SWG|reactome:R-HSA-9843970|panther:PTHR15836(orthology-group)"	"interpro:IPR028630|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016987""(sigma factor activity)|interpro:IPR042189|interpro:IPR036388|interpro:IPR050239"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/23	rogid:+s8KstGQ7d91qe3DDnpKYMJon7o9606	rogid:8NwL0C9CZc1yJ2fOOz9gZqJHCMI632	intact-crc:DAA7026B340D2DE8|rigid:ly5i16+FVsAQ+GWp3GX8m8ar4Gc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10619	uniprotkb:Q0WJT0	intact:EBI-989654|uniprotkb:Q9BW68|uniprotkb:Q561W6|uniprotkb:Q5JZH1|uniprotkb:Q96KJ2|uniprotkb:Q9BR08|uniprotkb:B2R798|ensembl:ENSP00000191018.5|ensembl:ENSP00000361537.2|ensembl:ENSP00000475524.2|ensembl:ENSP00000493613.2	intact:EBI-2848005|uniprotkb:A0A3N4BBH4|uniprotkb:Q74XB0|uniprotkb:A0A0H2W350|uniprotkb:Q7CKL8|uniprotkb:A0A384LB40	psi-mi:ppgb_human(display_long)|uniprotkb:Cathepsin A(gene name synonym)|uniprotkb:Carboxypeptidase C(gene name synonym)|uniprotkb:Protective protein for beta-galactosidase(gene name synonym)|uniprotkb:CTSA(gene name)|psi-mi:CTSA(display_short)|uniprotkb:PPGB(gene name synonym)|uniprotkb:Carboxypeptidase L(gene name synonym)|uniprotkb:Protective protein cathepsin A(gene name synonym)	psi-mi:q0wjt0_yerpe(display_long)|uniprotkb:rnr(gene name)|psi-mi:rnr(display_short)|uniprotkb:vacB(gene name synonym)|uniprotkb:YPO0380(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860831|imex:IM-13779-6560	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:351""|efo:""Orphanet:575553""|ensembl:ENSG00000064601.21(gene)|ensembl:ENST00000191018.9(transcript)|ensembl:ENST00000372459.7(transcript)|ensembl:ENST00000607482.6(transcript)|ensembl:ENST00000646241.3(transcript)|go:""GO:0004180""(carboxypeptidase activity)|go:""GO:0004185""(serine-type carboxypeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006508""(proteolysis)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0016020""(membrane)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904714""(regulation of chaperone-mediated autophagy)|go:""GO:1904715""(negative regulation of chaperone-mediated autophagy)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|interpro:IPR033124|mint:P10619|rcsb pdb:1IVY|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BXN|rcsb pdb:4AZ0|rcsb pdb:4AZ3|rcsb pdb:4CI9|rcsb pdb:4CIA|rcsb pdb:4CIB|rcsb pdb:4MWS|rcsb pdb:4MWT|rcsb pdb:6WIA|reactome:R-HSA-2132295|reactome:R-HSA-4085001|reactome:R-HSA-4341670|reactome:R-HSA-6798695|reactome:R-HSA-9840310|refseq:NP_000299.2|refseq:NP_001121167.1|refseq:NP_001161066.1|panther:PTHR11802(orthology-group)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011805(Ribonuclease R, bacterial)|interpro:IPR013668(Ribonuclease R winged-helix domain)|interpro:IPR040476|refseq:WP_002209159.1|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008859""(exoribonuclease II activity)|go:""GO:0016070""(RNA metabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:YP_002345458.1|interpro:IPR050180"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l/CZaKjZTuZu1ROoJJZVsxobYrQ9606	rogid:jBGTi4O5QHZXkNIanuHOpATLT7Q632	intact-crc:45279DD7AA2EECFC|rigid:h8cakIpqpThCXJg3oIkESYozBc0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P67775	uniprotkb:A0A2U2GZL1	intact:EBI-712311|uniprotkb:P05323|uniprotkb:P13197|ensembl:ENSP00000418447.1	intact:EBI-2854458|uniprotkb:Q74PS2|uniprotkb:Q0WB90|uniprotkb:A0A5P8YJZ1|uniprotkb:Q7CL96|uniprotkb:A0A384KMD8	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:a0a2u2gzl1_yerpe(display_long)|uniprotkb:pog(gene name)|psi-mi:pog(display_short)|uniprotkb:ssp(gene name synonym)|uniprotkb:sspA(gene name synonym)|uniprotkb:YPO3561(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860871|imex:IM-13779-6568	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000113575.13(gene)|ensembl:ENST00000481195.6(transcript)|go:""GO:0000159""(protein phosphatase type 2A complex)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000922""(spindle pole)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007498""(mesoderm development)|go:""GO:0008287""(protein serine/threonine phosphatase complex)|go:""GO:0010288""(response to lead ion)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035970""(peptidyl-threonine dephosphorylation)|go:""GO:0040008""(regulation of growth)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045595""(regulation of cell differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050811""(GABA receptor binding)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070262""(peptidyl-serine dephosphorylation)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1904528""(positive regulation of microtubule binding)|go:""GO:1904539""(negative regulation of glycolytic process through fructose-6-phosphate)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186(""Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase"")|interpro:IPR029052|interpro:IPR047129|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:4NY3|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|rcsb pdb:7PKS|rcsb pdb:7SOY|rcsb pdb:7YCX|rcsb pdb:8RBX|rcsb pdb:8RBZ|rcsb pdb:8RC4|rcsb pdb:8SO0|rcsb pdb:8TTB|rcsb pdb:8TWE|rcsb pdb:8TWI|rcsb pdb:8U1X|rcsb pdb:8U89|rcsb pdb:8UWB|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|reactome:R-HSA-9833482|reactome:R-HSA-9860927|refseq:NP_002706.1|efo:""Orphanet:528084""|dip:DIP-29395N|panther:PTHR45619(orthology-group)"	interpro:IPR050983|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|rcsb pdb:1YY7|refseq:WP_002210135.1|interpro:IPR034341|interpro:IPR040079|interpro:IPR036249|interpro:IPR036282|refseq:YP_002348448.1|interpro:IPR034342	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:9smmAt4ZQb55TC9gx1z1tyl4bTI632	intact-crc:AA1A984BC236976D|rigid:0Z816BLIXREpkNMZfwvoeZf8ReM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15435	uniprotkb:Q7ARD3	intact:EBI-1024281|uniprotkb:Q9UQE5|uniprotkb:Q9UQE6|uniprotkb:Q9Y6K4|uniprotkb:B4DFD4|uniprotkb:B5MCY6|ensembl:ENSP00000234038.6|ensembl:ENSP00000385657.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:pp1r7_human(display_long)|uniprotkb:Protein phosphatase 1 regulatory subunit 22(gene name synonym)|uniprotkb:PPP1R7(gene name)|psi-mi:PPP1R7(display_short)|uniprotkb:SDS22(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860885|imex:IM-13779-6567	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002703.1|refseq:NP_001269338.1|refseq:NP_001269339.1|refseq:NP_001269340.1|refseq:NP_001269341.1|refseq:NP_001269342.1|refseq:NP_001269343.1|dip:DIP-1005N|ensembl:ENSG00000115685.15(gene)|ensembl:ENST00000234038.11(transcript)|ensembl:ENST00000407025.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR025875|interpro:IPR032675|interpro:IPR050576|mint:Q15435|rcsb pdb:6HKW|rcsb pdb:6MKY|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:8B5R|rcsb pdb:8U5G|panther:PTHR45973(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HKHhTMtEgPpOdf/lS59bZAOrDjk9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:1694B17726295D81|rigid:yrFgeA9CVursMpOAty8DDpcJDs0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48454	uniprotkb:A0A3N4BNK4	intact:EBI-2827192|uniprotkb:Q9H4M5|uniprotkb:Q9BSS6|uniprotkb:B4DRT5|ensembl:ENSP00000240139.5	intact:EBI-2855448|uniprotkb:A0A380PK27|uniprotkb:Q0WDQ1|uniprotkb:Q7CJU1	psi-mi:pp2bc_human(display_long)|uniprotkb:PPP3CC(gene name)|psi-mi:PPP3CC(display_short)|uniprotkb:CALNA3(gene name synonym)|uniprotkb:CNA3(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Calcineurin, testis-specific catalytic subunit(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit gamma isoform(gene name synonym)	psi-mi:a0a3n4bnk4_yerpe(display_long)|uniprotkb:ybfM(gene name)|psi-mi:ybfM(display_short)|uniprotkb:YPO2631(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860864|imex:IM-13779-6565	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005596.2|refseq:NP_001230904.1|refseq:NP_001230903.1|ensembl:ENSG00000120910.15(gene)|ensembl:ENST00000240139.10(transcript)|go:""GO:0004723""(calcium-dependent protein serine/threonine phosphatase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005955""(calcineurin complex)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008287""(protein serine/threonine phosphatase complex)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0070886""(positive regulation of calcineurin-NFAT signaling cascade)|go:""GO:0097720""(calcineurin-mediated signaling)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1900244""(positive regulation of synaptic vesicle endocytosis)|go:""GO:1905665""(positive regulation of calcium ion import across plasma membrane)|go:""GO:1905949""(negative regulation of calcium ion import across plasma membrane)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186(""Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase"")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:P48454|rcsb pdb:7U0T|reactome:R-HSA-111447|reactome:R-HSA-180024|panther:PTHR45673(orthology-group)"	"interpro:IPR005318(Outer membrane porin, bacterial)|refseq:WP_002210355.1|go:""GO:0016020""(membrane)|interpro:IPR023614|refseq:YP_002347587.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kCGnmYnNPtbosNJTQdIZ9ye0JHk9606	rogid:kQOm62Hk7MNtNLAcnBC4bzThrBs632	intact-crc:6BF7042A76A9870D|rigid:yc7XinwYRPk5voKXRayjJqq/ryg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96QC0	uniprotkb:P17778	intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694.2|ensembl:ENSP00000373080.4|ensembl:ENSP00000389299.2|ensembl:ENSP00000407181.2|ensembl:ENSP00000407310.2|ensembl:ENSP00000413554.2|ensembl:ENSP00000416060.2	intact:EBI-2842665|uniprotkb:O68701	psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860878|imex:IM-13779-6566	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|ensembl:ENSG00000204569.10(gene)|ensembl:ENSG00000206489.9(gene)|ensembl:ENSG00000227804.7(gene)|ensembl:ENSG00000230995.7(gene)|ensembl:ENSG00000231737.7(gene)|ensembl:ENSG00000235291.7(gene)|ensembl:ENSG00000238104.7(gene)|ensembl:ENST00000376511.7(transcript)|ensembl:ENST00000383586.8(transcript)|ensembl:ENST00000420949.6(transcript)|ensembl:ENST00000424446.6(transcript)|ensembl:ENST00000426299.6(transcript)|ensembl:ENST00000429597.6(transcript)|ensembl:ENST00000449113.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0016604""(nuclear body)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0046872""(metal ion binding)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|go:""GO:1904290""(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|rcsb pdb:6ZV2|rcsb pdb:8SW5|dip:DIP-39343N|panther:PTHR47398(orthology-group)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:E33935C252BFE9E8|rigid:8yuqjchaFQFcqWIVkBUbL9oA0JQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62140	uniprotkb:Q8ZAQ2	intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122.6|ensembl:ENSP00000378769.2|ensembl:ENSP00000398839.2|ensembl:ENSP00000414918.2|ensembl:ENSP00000515219.1	intact:EBI-2860892|uniprotkb:Q0WAR9	psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short)	psi-mi:thic_yerpe(display_long)|uniprotkb:thiC(gene name)|psi-mi:thiC(display_short)|uniprotkb:YP_3102(locus name)|uniprotkb:Hydroxymethylpyrimidine phosphate synthase(gene name synonym)|uniprotkb:YPO3739(locus name)|uniprotkb:y0491(locus name)|uniprotkb:Thiamine biosynthesis protein ThiC(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860897|imex:IM-13779-6569	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000213639.11(gene)|ensembl:ENST00000296122.10(transcript)|ensembl:ENST00000395366.3(transcript)|ensembl:ENST00000420282.6(transcript)|ensembl:ENST00000441461.6(transcript)|ensembl:ENST00000703173.1(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0005977""(glycogen metabolic process)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0016791""(phosphatase activity)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043153""(entrainment of circadian clock by photoperiod)|go:""GO:0046872""(metal ion binding)|go:""GO:0050115""(myosin-light-chain-phosphatase activity)|go:""GO:0051301""(cell division)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186(""Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase"")|interpro:IPR029052|interpro:IPR031675|interpro:IPR050341|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9726840|reactome:R-HSA-9726842|reactome:R-HSA-9828806|refseq:NP_002700.1|refseq:NP_996759.1|efo:""Orphanet:2701""|dip:DIP-33220N|panther:PTHR11668(orthology-group)"	"interpro:IPR002817(Thiamine biosynthesis protein ThiC)|refseq:WP_002210682.1|interpro:IPR025747|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0016830""(carbon-carbon lyase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR038521|interpro:IPR037509|refseq:YP_002348619.1|panther:PTHR30557(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606	rogid:RVZL9aFEqXV/KORpQabcnqvxVkE632	intact-crc:3E1EAE2A79DEB1B3|rigid:LfErvO4R7ZWxenQZXxfccueHQLM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UBT6	uniprotkb:Q7ARD3	intact:EBI-2860904|uniprotkb:Q8NB30|uniprotkb:Q9UHC5|uniprotkb:Q96L01|uniprotkb:Q86VJ8|uniprotkb:Q8IZY0|uniprotkb:B2RBD2|uniprotkb:Q96Q86|uniprotkb:Q96Q87|uniprotkb:Q8IZY1|uniprotkb:Q5Q9G5|uniprotkb:Q5Q9G6|uniprotkb:Q5Q9G7|uniprotkb:Q5Q9G8|ensembl:ENSP00000241436.4	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:polk_human(display_long)|uniprotkb:POLK(gene name)|psi-mi:POLK(display_short)|uniprotkb:DINB1(gene name synonym)|uniprotkb:DINB protein(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860917|imex:IM-13779-6570	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057302.1|refseq:XP_016865048.1|refseq:XP_016865049.1|refseq:XP_016865052.1|refseq:NP_001332851.1|ensembl:ENSG00000122008.16(gene)|ensembl:ENST00000241436.9(transcript)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006297""(nucleotide-excision repair, DNA gap filling)|go:""GO:0006974""(DNA damage response)|go:""GO:0016604""(nuclear body)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042276""(error-prone translesion synthesis)|go:""GO:0046872""(metal ion binding)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR017961|interpro:IPR022880|interpro:IPR024728|interpro:IPR036775|interpro:IPR043128|interpro:IPR043502|interpro:IPR050116|rcsb pdb:1T94|rcsb pdb:2LSI|rcsb pdb:2OH2|rcsb pdb:2W7O|rcsb pdb:2W7P|rcsb pdb:3IN5|rcsb pdb:3PZP|rcsb pdb:4BA9|rcsb pdb:4GK5|rcsb pdb:4U6P|rcsb pdb:4U7C|rcsb pdb:5T14|rcsb pdb:5W2A|rcsb pdb:5W2C|rcsb pdb:6BRX|rcsb pdb:6BS1|rcsb pdb:6CST|rcsb pdb:7NV0|rcsb pdb:7NV1|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|panther:PTHR11076(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:93wVfgLrwZ0ZM0zbMqFBLlqps0o9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:A5B217CCC1C5AB22|rigid:kyVLkI/WhQzDAPSgmO3cHLvrEIs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q7Z3K3	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860924|imex:IM-13779-6571	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	intact-crc:6BF7771229AC3DBE|rigid:tzN+kig83Zx7LfsKjt2ldI2ymLw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3K3	uniprotkb:Q8ZFR0	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	intact:EBI-2857991|uniprotkb:Q0WGE6	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:pept_yerpe(display_long)|uniprotkb:pepT(gene name)|psi-mi:pepT(display_short)|uniprotkb:Aminotripeptidase(gene name synonym)|uniprotkb:Tripeptide aminopeptidase(gene name synonym)|uniprotkb:YPO1631(locus name)|uniprotkb:y1791(locus name)|uniprotkb:YP_1761(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860931|imex:IM-13779-6572	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR010161(Peptidase M20B, tripeptide aminopeptidase)|refseq:WP_002210920.1|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0045148""(tripeptide aminopeptidase activity)|interpro:IPR036264|refseq:YP_002346642.1|panther:PTHR42994(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:/sFvXfEC4pSnS9aI2zKFcuGUt+k632	intact-crc:C2094CE0F64D3D7A|rigid:4AsPAoTZdKJX+ZuWIEjY8uPgqek	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3K3	uniprotkb:P58543	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	intact:EBI-2847390|uniprotkb:Q0WER7	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:arab_yerpe(display_long)|uniprotkb:araB(gene name)|psi-mi:araB(display_short)|uniprotkb:YPO2254(locus name)|uniprotkb:y2095(locus name)|uniprotkb:YP_2050(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860975|imex:IM-13779-6577	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"interpro:IPR018485|interpro:IPR005929(L-ribulokinase)|interpro:IPR043129|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008741""(ribulokinase activity)|go:""GO:0019150""(D-ribulokinase activity)|go:""GO:0019321""(pentose metabolic process)|go:""GO:0019569""(L-arabinose catabolic process to xylulose 5-phosphate)|refseq:YP_002347221.1|panther:PTHR43435(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:hejpPk7Q+tUU+cmG5v4jTehB47I632	intact-crc:867C00D116CFDB2E|rigid:xJZLz1vJc0AMhjs58xTMGH0A+pw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3K3	uniprotkb:Q56989	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	intact:EBI-2860949|uniprotkb:Q0WK23	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:hmur_yerpe(display_long)|uniprotkb:hmuR(gene name)|psi-mi:hmuR(display_short)|uniprotkb:YPO0283(locus name)|uniprotkb:y0543(locus name)|uniprotkb:YP_0438(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860954|imex:IM-13779-6576	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR011276(TonB-dependent haem/haemoglobin receptor)|interpro:IPR010949(TonB-dependent haemoglobin/transferrin/lactoferrin receptor)|refseq:WP_002209062.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015232""(heme transmembrane transporter activity)|go:""GO:0015344""(siderophore uptake transmembrane transporter activity)|go:""GO:0044718""(siderophore transmembrane transport)|go:""GO:0071281""(cellular response to iron ion)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002345365.1|panther:PTHR30069(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:+01B95YakdqYxalnNbktgrTkIok632	intact-crc:DBCA14AFC9E34986|rigid:6cJIehQK9SXtFqmZshWEAGSZm8Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJF3	uniprotkb:Q7Z3K3	intact:EBI-2850095|uniprotkb:Q0WKE6	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	psi-mi:gph_yerpe(display_long)|uniprotkb:gph(gene name)|psi-mi:gph(display_short)|uniprotkb:YPO0156(locus name)|uniprotkb:y3939(locus name)|uniprotkb:YP_0158(locus name)	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860961|imex:IM-13779-6574	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|interpro:IPR037512|refseq:WP_002208892.1|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006281""(DNA repair)|go:""GO:0008967""(phosphoglycolate phosphatase activity)|go:""GO:0046295""(glycolate biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR036412|interpro:IPR041492|refseq:YP_002345242.1|interpro:IPR050155|panther:PTHR43434(orthology-group)"	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:n2m9iPEoLBOpfauijcWx/W/lq+M632	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	intact-crc:464300E0F6AC836F|rigid:ANMcwNMGMerXiu9gPJogv8so+Mg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA76	uniprotkb:Q7Z3K3	intact:EBI-2846943|uniprotkb:Q0WA76	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	psi-mi:glgx_yerpe(display_long)|uniprotkb:glgX(gene name)|psi-mi:glgX(display_short)|uniprotkb:Limit dextrin alpha-1,6-maltotetraose-hydrolase(gene name synonym)|uniprotkb:YPO3941(locus name)|uniprotkb:YP_3303(locus name)|uniprotkb:y3887(locus name)	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860968|imex:IM-13779-6575	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR022844|interpro:IPR011837(Glycogen debranching enzyme GlgX)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR040784|go:""GO:0004133""(obsolete glycogen debranching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005980""(glycogen catabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_002209499.1|interpro:IPR044505|refseq:YP_002348812.1|panther:PTHR43002(orthology-group)"	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8sHtj0obGqvrIdGE1JWk8okcbRM632	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	intact-crc:D2EE1BE0F7912F27|rigid:7uNROtvvSB2vJMteUnjMlX3cKJk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3K3	uniprotkb:P28808	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	intact:EBI-2860941	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:lcrf_yerpe(display_long)|uniprotkb:lcrF(gene name)|psi-mi:lcrF(display_short)|uniprotkb:virF(gene name synonym)|uniprotkb:YPCD1.49(locus name)|uniprotkb:y5029(locus name)|uniprotkb:y0032(locus name)|uniprotkb:YP_pCD34(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860938|imex:IM-13779-6573	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"refseq:NP_395183.1|refseq:NP_857733.1|refseq:NP_857928.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR018062|interpro:IPR018060|interpro:IPR020449|interpro:IPR054015|mint:P28808|refseq:WP_002212931.1|interpro:IPR050204|interpro:IPR037923|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0043565""(sequence-specific DNA binding)|panther:PTHR43280(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:yVpO1P2FvEEro9oVZYYjR90kz/M632	intact-crc:8C8D0FC343CC515B|rigid:ajkfH7uq0OzVYkZazN4AYxb4Cc0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3K3	uniprotkb:Q8ZGX4	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	intact:EBI-2840069|uniprotkb:Q74W78|uniprotkb:Q0WHQ0|uniprotkb:Q7CH64	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:6pgl_yerpe(display_long)|uniprotkb:pgl(gene name)|psi-mi:pgl(display_short)|uniprotkb:YPO1149(locus name)|uniprotkb:y3033(locus name)|uniprotkb:YP_1011(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860982|imex:IM-13779-6582	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"refseq:YP_002346188.1|interpro:IPR022528|interpro:IPR019405|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0009051""(pentose-phosphate shunt, oxidative branch)|go:""GO:0017057""(6-phosphogluconolactonase activity)|refseq:WP_002210760.1|interpro:IPR050282|panther:PTHR30344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:noKVC/wB8Hf1xbPbMQHTszCjTss632	intact-crc:C7BE3DE0F73C9EC6|rigid:l4nAggvPAZe2etb12Dp/MQeGm5g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01860	uniprotkb:A0A0H2W2N9	intact:EBI-475687|uniprotkb:P31359|uniprotkb:Q15167|uniprotkb:Q15168|uniprotkb:Q16422|uniprotkb:A6NCS1|uniprotkb:A6NLL8|uniprotkb:Q5STF3|uniprotkb:Q5STF4|uniprotkb:D2IYK4|ensembl:ENSP00000259915.7|ensembl:ENSP00000373016.4|ensembl:ENSP00000388842.2|ensembl:ENSP00000391681.2|ensembl:ENSP00000392877.2|ensembl:ENSP00000400047.2|ensembl:ENSP00000405041.2	intact:EBI-2840467|uniprotkb:Q74XT4|uniprotkb:Q0WBR4|uniprotkb:A0A384L498|uniprotkb:Q7CKD3|uniprotkb:A0A3N4B9W7	psi-mi:po5f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 3(gene name synonym)|uniprotkb:Octamer-binding protein 3(gene name synonym)|uniprotkb:POU5F1(gene name)|psi-mi:POU5F1(display_short)|uniprotkb:OCT3(gene name synonym)|uniprotkb:OCT4(gene name synonym)|uniprotkb:OTF3(gene name synonym)|uniprotkb:Octamer-binding protein 4(gene name synonym)	psi-mi:a0a0h2w2n9_yerpe(display_long)|uniprotkb:degP(gene name)|psi-mi:degP(display_short)|uniprotkb:gsrA(gene name synonym)|uniprotkb:htrA(gene name synonym)|uniprotkb:ptd(gene name synonym)|uniprotkb:YPO3382(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860989|imex:IM-13779-6578	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001272916.1|refseq:NP_002692.2|panther:PTHR11636(orthology-group)|ensembl:ENSG00000204531.21(gene)|ensembl:ENSG00000206454.12(gene)|ensembl:ENSG00000229094.9(gene)|ensembl:ENSG00000230336.9(gene)|ensembl:ENSG00000233911.9(gene)|ensembl:ENSG00000235068.9(gene)|ensembl:ENSG00000237582.10(gene)|ensembl:ENST00000259915.13(transcript)|ensembl:ENST00000383524.4(transcript)|ensembl:ENST00000429603.2(transcript)|ensembl:ENST00000433063.6(transcript)|ensembl:ENST00000434616.2(transcript)|ensembl:ENST00000437747.6(transcript)|ensembl:ENST00000454714.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001714""(endodermal cell fate specification)|go:""GO:0001824""(blastocyst development)|go:""GO:0003129""(heart induction)|go:""GO:0003133""(endodermal-mesodermal cell signaling)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0009611""(response to wounding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0009786""(regulation of asymmetric cell division)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0035198""(miRNA binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0060795""(cell fate commitment involved in formation of primary germ layer)|go:""GO:0060913""(cardiac cell fate determination)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|interpro:IPR050255|mint:Q01860|rcsb pdb:6T90|rcsb pdb:6YOV|rcsb pdb:7U0G|rcsb pdb:7U0I|rcsb pdb:8G87|rcsb pdb:8G88|rcsb pdb:8G8B|rcsb pdb:8G8E|rcsb pdb:8G8G|rcsb pdb:8OTS|rcsb pdb:8SPS|rcsb pdb:8SPU|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-452723|reactome:R-HSA-9754189|reactome:R-HSA-9823739|reactome:R-HSA-9827857|reactome:R-HSA-9834899|dip:DIP-33440N"	"interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:WP_002209370.1|refseq:YP_002348274.1|interpro:IPR036034"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eMEp6g1n+kU2YnuRprn2B79q7OM9606	rogid:wh5TqHAdstARdvvFDyS2kqzSnxY632	intact-crc:DD5C8AF9740623F4|rigid:1n0UnTHFAG2Z28yxgRoXDLJPTOw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARK4	uniprotkb:P14859	intact:EBI-2849202|uniprotkb:Q74YZ8|uniprotkb:Q7ARG6|uniprotkb:Q7BT15|intact:EBI-2862232|uniprotkb:A0A3G5L2H4|uniprotkb:A0A1U8QNS3|uniprotkb:Q7CL24|uniprotkb:Q7CI35	intact:EBI-624770|uniprotkb:Q5TBT7|uniprotkb:Q6PK46|uniprotkb:Q8NEU9|uniprotkb:Q9BPV1|intact:EBI-28988911|uniprotkb:B1AL91|uniprotkb:B1AL93|ensembl:ENSP00000441285.2|uniprotkb:B4E029|uniprotkb:J3KP77	psi-mi:q7ark4_yerpe(display_long)|uniprotkb:ypmt1.57c(gene name)|psi-mi:ypmt1.57c(display_short)|uniprotkb:Y0016(gene name synonym)|uniprotkb:DNA replication protein DnaC(gene name synonym)|uniprotkb:YPO0030(locus name)|uniprotkb:YPO0096(locus name)|uniprotkb:YPO0172(locus name)|uniprotkb:YPO0248(locus name)|uniprotkb:YPO0385(locus name)|uniprotkb:YPO0527(locus name)|uniprotkb:YPO0566(locus name)|uniprotkb:YPO0638(locus name)|uniprotkb:YPO0779(locus name)|uniprotkb:YPO0825(locus name)|uniprotkb:YPO0923(locus name)|uniprotkb:YPO1014(locus name)|uniprotkb:YPO1085(locus name)|uniprotkb:YPO1131(locus name)|uniprotkb:YPO1339(locus name)|uniprotkb:YPO1426(locus name)|uniprotkb:YPO1519(locus name)|uniprotkb:YPO1622(locus name)|uniprotkb:YPO1691(locus name)|uniprotkb:YPO1730(locus name)|uniprotkb:YPO1751(locus name)|uniprotkb:YPO1901(locus name)|uniprotkb:YPO2025(locus name)|uniprotkb:YPO2086(locus name)|uniprotkb:YPO2177(locus name)|uniprotkb:YPO2364(locus name)|uniprotkb:YPO2397(locus name)|uniprotkb:YPO2517(locus name)|uniprotkb:YPO2642(locus name)|uniprotkb:YPO2722(locus name)|uniprotkb:YPO2809(locus name)|uniprotkb:YPO2931(locus name)|uniprotkb:YPO3208(locus name)|uniprotkb:YPO3252(locus name)|uniprotkb:YPO3283(locus name)|uniprotkb:YPO3435(locus name)|uniprotkb:YPO3543(locus name)|uniprotkb:YPO3592(locus name)|uniprotkb:YPO3700(locus name)|uniprotkb:YPO3755(locus name)|uniprotkb:YPO3773(locus name)|uniprotkb:YPO4009(locus name)|uniprotkb:YPPCP1.02(locus name)|uniprotkb:YPMT1.02(locus name)|uniprotkb:YPMT1.57c(locus name)	psi-mi:po2f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:NF-A1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2860996|imex:IM-13779-6581	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001317493.1|refseq:NP_395228.1|refseq:NP_395337.2|refseq:NP_395401.1|refseq:NP_857912.1|refseq:YP_094026.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002611(IstB-like ATP-binding protein)|interpro:IPR028350|interpro:IPR027417|interpro:IPR047661|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006260""(DNA replication)|go:""GO:0006269""(DNA replication, synthesis of primer)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:1990077""(primosome complex)|refseq:YP_002345126.1|refseq:YP_002345187.1|refseq:YP_002345257.1|refseq:YP_002345329.1|refseq:YP_002345462.1|refseq:YP_002345600.1|refseq:YP_002345637.1|refseq:YP_002345705.1|refseq:YP_002345835.1|refseq:YP_002345879.1|refseq:YP_002345971.1|refseq:YP_002346057.1|refseq:YP_002346128.1|refseq:YP_002346173.1|refseq:YP_002346363.1|refseq:YP_002346449.1|refseq:YP_002346535.1|refseq:YP_002346633.1|refseq:YP_002346694.1|refseq:YP_002346731.1|refseq:YP_002346751.1|refseq:YP_002346891.1|refseq:YP_002347009.1|refseq:YP_002347067.1|refseq:YP_002347151.1|refseq:YP_002347331.1|refseq:YP_002347363.1|refseq:YP_002347481.1|refseq:YP_002347595.1|refseq:YP_002347669.1|refseq:YP_002347750.1|refseq:YP_002347861.1|refseq:YP_002348111.1|refseq:YP_002348153.1|refseq:YP_002348182.1|refseq:YP_002348327.1|refseq:YP_002348431.1|refseq:YP_002348477.1|refseq:YP_002348582.1|refseq:YP_002348635.1|refseq:YP_002348651.1|refseq:YP_002348876.1|panther:PTHR30050(orthology-group)"	"refseq:NP_001185715.1|ensembl:ENSG00000143190.23(gene)|ensembl:ENST00000541643.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1902895""(positive regulation of miRNA transcription)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|interpro:IPR045703|interpro:IPR050255|mint:P14859|rcsb pdb:1CQT|rcsb pdb:1E3O|rcsb pdb:1GT0|rcsb pdb:1HF0|rcsb pdb:1O4X|rcsb pdb:1OCT|rcsb pdb:1POG|rcsb pdb:1POU|reactome:R-HSA-6785807|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|reactome:R-HSA-9018519|refseq:NP_001185712.1|refseq:NP_002688.3|refseq:XP_011507956.1|dip:DIP-226N|panther:PTHR11636(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yqskl8o49hYONtduM+rZmKno4uU632	rogid:znBO7MSmTt52C2Lr6il25Hb9OBc9606	intact-crc:738EC3746D65293C|rigid:CeN1u/r8fD+o/pnbqRQp6iW5sWE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96HA1	uniprotkb:P69961	intact:EBI-739990|uniprotkb:A8MXF9|uniprotkb:O75115|uniprotkb:Q9Y4S7|intact:EBI-948778|uniprotkb:A6NFS9|uniprotkb:A8CDT4|uniprotkb:A8K933|uniprotkb:Q96DI0|uniprotkb:Q9H9X1|uniprotkb:Q9Y2N3|ensembl:ENSP00000405562.2	intact:EBI-2847280|uniprotkb:Q663H6|uniprotkb:Q00931	psi-mi:p121a_human(display_long)|uniprotkb:POM121(gene name)|psi-mi:POM121(display_short)|uniprotkb:KIAA0618(gene name synonym)|uniprotkb:NUP121(gene name synonym)|uniprotkb:POM121A(gene name synonym)|uniprotkb:Pore membrane protein of 121 kDa(gene name synonym)|uniprotkb:Nuclear envelope pore membrane protein POM 121A(gene name synonym)|uniprotkb:Nucleoporin Nup121(gene name synonym)	psi-mi:lcrs_yerpe(display_long)|uniprotkb:lcrS(gene name)|psi-mi:lcrS(display_short)|uniprotkb:YPCD1.63(locus name)|uniprotkb:y5015(locus name)|uniprotkb:y0018(locus name)|uniprotkb:YP_pCD20(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861010|imex:IM-13779-6580	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001244119.1|refseq:NP_742017.1|refseq:XP_005250783.1|refseq:XP_006716259.1|ensembl:ENSG00000196313.13(gene)|ensembl:ENST00000434423.5(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0031965""(nuclear membrane)|go:""GO:0051028""(mRNA transport)|interpro:IPR026054|mint:Q96HA1|rcsb pdb:5T6W|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9705671|refseq:XP_016868342.1|refseq:XP_016868343.1|panther:PTHR23193(orthology-group)"	"interpro:IPR002514(Transposase IS3/IS911)|refseq:NP_395197.1|refseq:NP_857719.1|refseq:NP_857914.1|interpro:IPR009057(Homeodomain-like)|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|interpro:IPR052546|panther:PTHR33609(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lQ9VaBl42KMRJaM4UdF4ng9ZX549606	rogid:qN+XjQYD6AUbLCv9ZgB3dougULw632	intact-crc:29CB57E96BB0DB8E|rigid:nWeO6xufm9JiKoAV7KF1BuDcfuo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96HA1	uniprotkb:Q8D014	intact:EBI-739990|uniprotkb:A8MXF9|uniprotkb:O75115|uniprotkb:Q9Y4S7|intact:EBI-948778|uniprotkb:A6NFS9|uniprotkb:A8CDT4|uniprotkb:A8K933|uniprotkb:Q96DI0|uniprotkb:Q9H9X1|uniprotkb:Q9Y2N3|ensembl:ENSP00000405562.2	intact:EBI-2840312|uniprotkb:Q74WE9	psi-mi:p121a_human(display_long)|uniprotkb:POM121(gene name)|psi-mi:POM121(display_short)|uniprotkb:KIAA0618(gene name synonym)|uniprotkb:NUP121(gene name synonym)|uniprotkb:POM121A(gene name synonym)|uniprotkb:Pore membrane protein of 121 kDa(gene name synonym)|uniprotkb:Nuclear envelope pore membrane protein POM 121A(gene name synonym)|uniprotkb:Nucleoporin Nup121(gene name synonym)	psi-mi:q8d014_yerpe(display_long)|uniprotkb:nrdB(gene name)|psi-mi:nrdB(display_short)|uniprotkb:y2975(locus name)|uniprotkb:YP_0924(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861003|imex:IM-13779-6579	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001244119.1|refseq:NP_742017.1|refseq:XP_005250783.1|refseq:XP_006716259.1|ensembl:ENSG00000196313.13(gene)|ensembl:ENST00000434423.5(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0031965""(nuclear membrane)|go:""GO:0051028""(mRNA transport)|interpro:IPR026054|mint:Q96HA1|rcsb pdb:5T6W|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9705671|refseq:XP_016868342.1|refseq:XP_016868343.1|panther:PTHR23193(orthology-group)"	"interpro:IPR033909|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|go:""GO:0004748""(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:""GO:0009263""(deoxyribonucleotide biosynthetic process)|interpro:IPR030475|interpro:IPR012348(Ribonucleotide reductase-related)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lQ9VaBl42KMRJaM4UdF4ng9ZX549606	rogid:cQYray4oIRTe9sYOcO6GpVOCuBc632	intact-crc:AA697E7019EF4D44|rigid:VIX9I1MEwbCQgM9bF30dgT3aqiE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01453	uniprotkb:A0A3G5L195	intact:EBI-2845982|uniprotkb:Q8WV01|ensembl:ENSP00000308937.3|ensembl:ENSP00000484631.1|ensembl:ENSP00000501546.1|ensembl:ENSP00000501557.1|ensembl:ENSP00000501727.1|ensembl:ENSP00000501804.1|ensembl:ENSP00000502018.1|ensembl:ENSP00000502310.1|ensembl:ENSP00000502601.1|ensembl:ENSP00000502835.1	intact:EBI-2846239	psi-mi:pmp22_human(display_long)|uniprotkb:PMP22(gene name)|psi-mi:PMP22(display_short)|uniprotkb:GAS3(gene name synonym)|uniprotkb:Growth arrest-specific protein 3(gene name synonym)	psi-mi:a0a3g5l195_yerpe(display_long)|uniprotkb:gltD_2(gene name synonym)|uniprotkb:NCTC5923_03556(orf name)|uniprotkb:YP_0496(locus name)|uniprotkb:y0599(locus name)|uniprotkb:gltD1(gene name)|psi-mi:gltD1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861024|imex:IM-13779-6586	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109099.16(gene)|ensembl:ENST00000312280.9(transcript)|ensembl:ENST00000612492.5(transcript)|ensembl:ENST00000674651.1(transcript)|ensembl:ENST00000674673.1(transcript)|ensembl:ENST00000674868.1(transcript)|ensembl:ENST00000675350.1(transcript)|ensembl:ENST00000675808.1(transcript)|ensembl:ENST00000675819.1(transcript)|ensembl:ENST00000675950.1(transcript)|ensembl:ENST00000676221.1(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006915""(apoptotic process)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007422""(peripheral nervous system development)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0030154""(cell differentiation)|go:""GO:0032060""(bleb assembly)|go:""GO:0032288""(myelin assembly)|go:""GO:0043218""(compact myelin)|go:""GO:0045202""(synapse)|interpro:IPR003936(Peripheral myelin protein PMP22)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20)|interpro:IPR050579|reactome:R-HSA-9619665|refseq:NP_000295.1|refseq:NP_001268384.1|refseq:NP_001268385.1|refseq:NP_696996.1|refseq:NP_696997.1|efo:""Orphanet:101081""|efo:""Orphanet:3115""|efo:""Orphanet:640""|efo:""Orphanet:64748""|efo:""Orphanet:90658""|efo:""Orphanet:98916""|panther:PTHR10671(orthology-group)"	"go:""GO:0016491""(oxidoreductase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|uniprotkb:A0A0H2W2I9(uniprot-removed-ac)|interpro:IPR006006(Glutamate synthase, NADH/NADPH, small subunit 2)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR017896|interpro:IPR017900|interpro:IPR023753|interpro:IPR028261|interpro:IPR036188|refseq:WP_002209118.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8GEEj1AMDasftvESZoQzybDVtKI9606	rogid:O695WmNy+GxlzKIxVsZgUG5sXkQ632	intact-crc:D7E24894860E5271|rigid:LqDObM5P2TVD/Brsh/++GUtcTqM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TBY8	uniprotkb:Q8CZZ7	intact:EBI-2827396|uniprotkb:Q9BY16|uniprotkb:Q8NA09|uniprotkb:Q9H0H4|uniprotkb:B3KVI9|uniprotkb:H7BY07|ensembl:ENSP00000237353.10|uniprotkb:G3V1Q7	intact:EBI-2842831|uniprotkb:Q74W48	psi-mi:pmfbp_human(display_long)|uniprotkb:PMFBP1(gene name)|psi-mi:PMFBP1(display_short)	psi-mi:q8czz7_yerpe(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:YP_1051(locus name)|uniprotkb:y3075(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861031|imex:IM-13779-6584	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000118557.16(gene)|ensembl:ENST00000237353.15(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007286""(spermatid development)|go:""GO:0008104""(protein localization)|go:""GO:0010467""(gene expression)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0036126""(sperm flagellum)|go:""GO:0061827""(sperm head)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0120212""(sperm head-tail coupling apparatus)|interpro:IPR037391|refseq:NP_001153685.1|refseq:NP_112583.2|efo:""Orphanet:529970""|panther:PTHR18881(orthology-group)"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xw2dXXywgzNwpgUYjM6SkWZwe3M9606	rogid:5D57QZRbHjtu2izZZ+54f7spmuk632	intact-crc:12D428926084B7F3|rigid:bmx5e+gJomgO0lHxTB932y5sQ2E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15031	uniprotkb:A0A3G5LAS3	intact:EBI-722004|uniprotkb:Q7KZU3|uniprotkb:Q9BSU7|uniprotkb:A6QRH0|ensembl:ENSP00000352288.4|ensembl:ENSP00000409171.1	intact:EBI-2858353|uniprotkb:A0A1U8QWA8|uniprotkb:Q74YJ3|uniprotkb:Q9ZGY3|uniprotkb:Q7ARA8|uniprotkb:A0A0H2W1Z2|uniprotkb:A0A384LAQ1	psi-mi:plxb2_human(display_long)|uniprotkb:MM1(gene name synonym)|uniprotkb:PLXNB2(gene name)|psi-mi:PLXNB2(display_short)|uniprotkb:KIAA0315(gene name synonym)	psi-mi:a0a3g5las3_yerpe(display_long)|uniprotkb:YPMT1.86c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861038|imex:IM-13779-6585	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036533.2|refseq:XP_005261966.1|refseq:XP_005261967.1|refseq:XP_005261968.1|refseq:XP_006724476.1|ensembl:ENSG00000196576.16(gene)|ensembl:ENST00000359337.9(transcript)|ensembl:ENST00000449103.5(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002116""(semaphorin receptor complex)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007416""(synapse assembly)|go:""GO:0007420""(brain development)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0050772""(positive regulation of axonogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:1904861""(excitatory synapse assembly)|go:""GO:2001222""(regulation of neuron migration)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR046800|mint:O15031|rcsb pdb:4E71|refseq:XP_016884192.1|refseq:XP_016884193.1|panther:PTHR22625(orthology-group)"	refseq:NP_395432.1|refseq:WP_002228802.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vUQ49+gukzUJkXbZKmcztEequc49606	rogid:7tH07Yv4XPfqK+U1ZykbkUm6Uuk632	intact-crc:5ED09FD0BB9CB213|rigid:1QuGjXlXWoZ+WNPCDdSi2rtV2Cc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W5H8	uniprotkb:Q96T60	intact:EBI-2844517|uniprotkb:Q74U50|uniprotkb:Q0WFA4|uniprotkb:Q7CIB9|uniprotkb:A0A380PCV3|uniprotkb:A0A384K834	intact:EBI-1045072|uniprotkb:Q9P1V2|uniprotkb:Q9UKU8|uniprotkb:Q9UNF8|uniprotkb:Q9UNI0|uniprotkb:Q9BUL2|ensembl:ENSP00000323511.2|ensembl:ENSP00000472300.1	psi-mi:a0a0h2w5h8_yerpe(display_long)|uniprotkb:YPO2052(locus name)	psi-mi:pnkp_human(display_long)|uniprotkb:Polynucleotide kinase-3'-phosphatase(gene name synonym)|uniprotkb:DNA 5'-kinase/3'-phosphatase(gene name synonym)|uniprotkb:PNKP(gene name)|psi-mi:PNKP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861017|imex:IM-13779-6583	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR002763(Protein of unknown function DUF72)|refseq:WP_002211205.1|interpro:IPR036520|refseq:YP_002347034.1	"efo:""Orphanet:101101""|efo:""Orphanet:1934""|efo:""Orphanet:459033""|ensembl:ENSG00000039650.12(gene)|ensembl:ENST00000322344.8(transcript)|ensembl:ENST00000596014.5(transcript)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006287""(base-excision repair, gap-filling)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0009314""(response to radiation)|go:""GO:0010836""(negative regulation of protein ADP-ribosylation)|go:""GO:0016020""(membrane)|go:""GO:0017076""(purine nucleotide binding)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0035861""(site of double-strand break)|go:""GO:0046403""(polynucleotide 3'-phosphatase activity)|go:""GO:0046404""(ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity)|go:""GO:0051103""(obsolete DNA ligation involved in DNA repair)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR006549(HAD-superfamily hydrolase, subfamily IIIA)|interpro:IPR006550(Polynucleotide kinase 3-phosphatase)|interpro:IPR006551(DNA 3-phosphatase)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013954(Polynucleotide kinase 3 phosphatase, central region)|interpro:IPR023214|interpro:IPR027417|interpro:IPR036412|interpro:IPR041388|mint:Q96T60|rcsb pdb:2BRF|rcsb pdb:2W3O|reactome:R-HSA-5649702|refseq:NP_009185.2|panther:PTHR12083(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yEDCK2RsoQ26AbDYmB6g8rBQ2+o632	rogid:wlLm6ja4qrCmWB44mE+C4w3wnyQ9606	intact-crc:DE70171A25C2E7B8|rigid:wvgih/sU8I4pcxZ8gfLwnIpYwM0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZEL7	uniprotkb:O15031	intact:EBI-2844441|uniprotkb:Q0WF15	intact:EBI-722004|uniprotkb:Q7KZU3|uniprotkb:Q9BSU7|uniprotkb:A6QRH0|ensembl:ENSP00000352288.4|ensembl:ENSP00000409171.1	psi-mi:dada_yerpe(display_long)|uniprotkb:dadA(gene name)|psi-mi:dadA(display_short)|uniprotkb:YPO2147(locus name)|uniprotkb:y2174(locus name)|uniprotkb:YP_1948(locus name)	psi-mi:plxb2_human(display_long)|uniprotkb:MM1(gene name synonym)|uniprotkb:PLXNB2(gene name)|psi-mi:PLXNB2(display_short)|uniprotkb:KIAA0315(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861045|imex:IM-13779-6587	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023080|interpro:IPR006076(FAD dependent oxidoreductase)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008718""(D-amino-acid dehydrogenase activity)|go:""GO:0055130""(D-alanine catabolic process)|refseq:WP_002211686.1|interpro:IPR036188|refseq:YP_002347123.1|panther:PTHR13847(orthology-group)"	"refseq:NP_036533.2|refseq:XP_005261966.1|refseq:XP_005261967.1|refseq:XP_005261968.1|refseq:XP_006724476.1|ensembl:ENSG00000196576.16(gene)|ensembl:ENST00000359337.9(transcript)|ensembl:ENST00000449103.5(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002116""(semaphorin receptor complex)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007416""(synapse assembly)|go:""GO:0007420""(brain development)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0050772""(positive regulation of axonogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:1904861""(excitatory synapse assembly)|go:""GO:2001222""(regulation of neuron migration)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR046800|mint:O15031|rcsb pdb:4E71|refseq:XP_016884192.1|refseq:XP_016884193.1|panther:PTHR22625(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oBXUXNHRC9vQGDI87OKH88hNmMw632	rogid:vUQ49+gukzUJkXbZKmcztEequc49606	intact-crc:77497CE9AAB3842A|rigid:6HOr3Z7fIJwqRtCuSgGcHqdOyug	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BX97	uniprotkb:Q56974	intact:EBI-2803560|uniprotkb:Q8ND68|uniprotkb:Q9BZD5|uniprotkb:Q8TER8|uniprotkb:Q86VP0|uniprotkb:Q8N8Y0|ensembl:ENSP00000252590.3	intact:EBI-2861069|uniprotkb:Q74YX8|uniprotkb:Q7BTX6|uniprotkb:A0A0H2W163	psi-mi:plvap_human(display_long)|uniprotkb:FELS(gene name synonym)|uniprotkb:PV1(gene name synonym)|uniprotkb:Fenestrated endothelial-linked structure protein(gene name synonym)|uniprotkb:Plasmalemma vesicle protein 1(gene name synonym)|uniprotkb:PLVAP(gene name)|psi-mi:PLVAP(display_short)	psi-mi:sctc_yerpe(display_long)|uniprotkb:sctC(gene name)|psi-mi:sctC(display_short)|uniprotkb:Type III secretion protein YscC(gene name synonym)|uniprotkb:yscC(gene name synonym)|uniprotkb:YPCD1.52(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861066|imex:IM-13779-6591	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000130300.9(gene)|ensembl:ENST00000252590.9(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0002693""(positive regulation of cellular extravasation)|go:""GO:0005901""(caveola)|go:""GO:0009986""(cell surface)|go:""GO:0032502""(developmental process)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043114""(regulation of vascular permeability)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|interpro:IPR009538(PV-1)|refseq:NP_112600.1|efo:""Orphanet:329242""|panther:PTHR21687(orthology-group)"	"interpro:IPR005644(NolW-like)|interpro:IPR004846(Type II and III secretion system)|interpro:IPR004845(Type II secretion system gspD, conserved site)|interpro:IPR003522(Type III secretion system outer membrane pore YscC/HrcC)|refseq:NP_857730.1|refseq:NP_857925.1|refseq:NP_395186.1|refseq:WP_002212923.1|interpro:IPR050810|interpro:IPR038591|go:""GO:0009279""(cell outer membrane)|go:""GO:0009306""(protein secretion)|go:""GO:0015627""(type II protein secretion system complex)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|interpro:IPR049034|panther:PTHR30332(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:B2XiKCX2HgPicALeBR9ePpTFLu49606	rogid:5xlTM71wKRUKMa1DaeOrn2PC4HY632	intact-crc:FCD6C6F87C2AE8DC|rigid:FWL7z7Z5JD/C9e0MVWisBeYjLOI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13796	uniprotkb:A0A0H2W0Z5	intact:EBI-698036|uniprotkb:Q5TBN4|uniprotkb:B2R613|ensembl:ENSP00000315757.2|ensembl:ENSP00000381581.1|uniprotkb:B4DUA0	intact:EBI-2844986|uniprotkb:Q74Y40|uniprotkb:Q0WKG8|uniprotkb:Q7CFX1|uniprotkb:A0A380PIN3|uniprotkb:A0A384LBS1	psi-mi:plsl_human(display_long)|uniprotkb:L-plastin(gene name synonym)|uniprotkb:Lymphocyte cytosolic protein 1(gene name synonym)|uniprotkb:LC64P(gene name synonym)|uniprotkb:LCP1(gene name)|psi-mi:LCP1(display_short)|uniprotkb:PLS2(gene name synonym)	psi-mi:a0a0h2w0z5_yerpe(display_long)|uniprotkb:YPO0134(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861084|imex:IM-13779-6590	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002289.2|refseq:XP_005266431.1|ensembl:ENSG00000136167.15(gene)|ensembl:ENST00000323076.7(transcript)|ensembl:ENST00000398576.6(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002102""(podosome)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0010737""(protein kinase A signaling)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016477""(cell migration)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030054""(cell junction)|go:""GO:0030175""(filopodium)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0032432""(actin filament bundle)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033157""(regulation of intracellular protein transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051020""(GTPase binding)|go:""GO:0051639""(actin filament network formation)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0097386""(glial cell projection)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039959|mint:P13796|rcsb pdb:2D85|rcsb pdb:5JOJ|rcsb pdb:5JOL|rcsb pdb:6VEC|reactome:R-HSA-8950505|dip:DIP-34767N|panther:PTHR19961(orthology-group)"	"interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR023323|interpro:IPR023319|interpro:IPR018974|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR044146|refseq:WP_002208916.1|go:""GO:0003676""(nucleic acid binding)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|interpro:IPR055179|interpro:IPR032639|interpro:IPR037027|interpro:IPR041692|refseq:YP_002345220.1|interpro:IPR050437"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/23	rogid:1uy1zhroB3GHUiAwLjEdP5Rz1xM9606	rogid:ttlZGvCMP/bbGv1PpYdheTErKIk632	intact-crc:BDAE5DD499EDCC88|rigid:mPO8l34sULyPQTF3nXxIgoS1+mQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43157	uniprotkb:A0A3G5KZU3	intact:EBI-1111488|uniprotkb:Q6NY20|uniprotkb:Q9UIV7|uniprotkb:Q9UJ92|uniprotkb:Q9UJ93|uniprotkb:A6H8Y2|ensembl:ENSP00000296440.6|ensembl:ENSP00000351338.4	intact:EBI-2850940	psi-mi:plxb1_human(display_long)|uniprotkb:PLXNB1(gene name)|psi-mi:PLXNB1(display_short)|uniprotkb:KIAA0407(gene name synonym)|uniprotkb:SEP(gene name synonym)|uniprotkb:Semaphorin receptor SEP(gene name synonym)|uniprotkb:PLXN5(gene name synonym)	psi-mi:a0a3g5kzu3_yerpe(display_long)|uniprotkb:y0245(locus name)|uniprotkb:ssuA(gene name)|psi-mi:ssuA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861052|imex:IM-13779-6592	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123554.1|refseq:NP_002664.2|refseq:XP_016862120.1|ensembl:ENSG00000164050.13(gene)|ensembl:ENST00000296440.11(transcript)|ensembl:ENST00000358536.8(transcript)|go:""GO:0002116""(semaphorin receptor complex)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007416""(synapse assembly)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016477""(cell migration)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0030215""(semaphorin receptor binding)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0033689""(negative regulation of osteoblast proliferation)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0043931""(ossification involved in bone maturation)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0050772""(positive regulation of axonogenesis)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1904862""(inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|interpro:IPR046800|mint:O43157|rcsb pdb:2JPH|rcsb pdb:2OS6|rcsb pdb:2R2O|rcsb pdb:2REX|rcsb pdb:3HM6|rcsb pdb:3OL2|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:5B4W|rcsb pdb:7VF3|rcsb pdb:7VG7|rcsb pdb:8B3K|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-9013405|dip:DIP-36742N|panther:PTHR22625(orthology-group)"	"interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR010067(ABC transporter, substrate-binding protein, aliphatic sulphonates)|interpro:IPR015168(NMT1/THI5 like)|uniprotkb:A0A6B3T643(uniprot-removed-ac)|go:""GO:0016020""(membrane)|go:""GO:0042597""(periplasmic space)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|refseq:WP_002220949.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wWC3lipQ3PIBCvCjt5t2gQTAXro9606	rogid:kuMqjHfkYUIBJ4hy+1j+bwqjjo4632	intact-crc:CC61B4FFDC609A80|rigid:PvNzENXJAcqFGDZ2Ubg8x0zpyFM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6M0NNK5	uniprotkb:Q9BX97	intact:EBI-2846580	intact:EBI-2803560|uniprotkb:Q8ND68|uniprotkb:Q9BZD5|uniprotkb:Q8TER8|uniprotkb:Q86VP0|uniprotkb:Q8N8Y0|ensembl:ENSP00000252590.3	psi-mi:a0a6m0nnk5_yerpe(display_long)|uniprotkb:y1846(locus name)	psi-mi:plvap_human(display_long)|uniprotkb:FELS(gene name synonym)|uniprotkb:PV1(gene name synonym)|uniprotkb:Fenestrated endothelial-linked structure protein(gene name synonym)|uniprotkb:Plasmalemma vesicle protein 1(gene name synonym)|uniprotkb:PLVAP(gene name)|psi-mi:PLVAP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861059|imex:IM-13779-6588	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T7I9(uniprot-removed-ac)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR008640(Hep/Hag)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0019867""(outer membrane)"	"ensembl:ENSG00000130300.9(gene)|ensembl:ENST00000252590.9(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0002693""(positive regulation of cellular extravasation)|go:""GO:0005901""(caveola)|go:""GO:0009986""(cell surface)|go:""GO:0032502""(developmental process)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043114""(regulation of vascular permeability)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|interpro:IPR009538(PV-1)|refseq:NP_112600.1|efo:""Orphanet:329242""|panther:PTHR21687(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yL2m6VTkA9R9Q4e4kurjcWXhQOY632	rogid:B2XiKCX2HgPicALeBR9ePpTFLu49606	intact-crc:2C88A7D26379AEB8|rigid:hu5tJk3mr966E78zTnXr/Y6mt84	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZDG9	uniprotkb:Q9BX97	intact:EBI-2846543|uniprotkb:Q0WDT3	intact:EBI-2803560|uniprotkb:Q8ND68|uniprotkb:Q9BZD5|uniprotkb:Q8TER8|uniprotkb:Q86VP0|uniprotkb:Q8N8Y0|ensembl:ENSP00000252590.3	psi-mi:lipb_yerpe(display_long)|uniprotkb:lipB(gene name)|psi-mi:lipB(display_short)|uniprotkb:Lipoate-protein ligase B(gene name synonym)|uniprotkb:Lipoyl/octanoyl transferase(gene name synonym)|uniprotkb:Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase(gene name synonym)|uniprotkb:YPO2599(locus name)|uniprotkb:y1173(locus name)|uniprotkb:YP_1114(locus name)	psi-mi:plvap_human(display_long)|uniprotkb:FELS(gene name synonym)|uniprotkb:PV1(gene name synonym)|uniprotkb:Fenestrated endothelial-linked structure protein(gene name synonym)|uniprotkb:Plasmalemma vesicle protein 1(gene name synonym)|uniprotkb:PLVAP(gene name)|psi-mi:PLVAP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861077|imex:IM-13779-6589	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004143(Biotin/lipoate A/B protein ligase)|interpro:IPR000544(Lipoate-protein ligase B)|interpro:IPR020605|refseq:WP_002218201.1|go:""GO:0005737""(cytoplasm)|go:""GO:0033819""(""lipoyl(octanoyl) transferase activity"")|interpro:IPR045864|panther:PTHR10993(orthology-group)"	"ensembl:ENSG00000130300.9(gene)|ensembl:ENST00000252590.9(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0002693""(positive regulation of cellular extravasation)|go:""GO:0005901""(caveola)|go:""GO:0009986""(cell surface)|go:""GO:0032502""(developmental process)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043114""(regulation of vascular permeability)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|interpro:IPR009538(PV-1)|refseq:NP_112600.1|efo:""Orphanet:329242""|panther:PTHR21687(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hReS04IYeo8x9cJJiZM0jH7goUg632	rogid:B2XiKCX2HgPicALeBR9ePpTFLu49606	intact-crc:26D57CB742F0F08E|rigid:Ou6B2+zS1wHDSQfdkd0wqJlRuy0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NRY6	uniprotkb:A0A3N4BEU0	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021.11|ensembl:ENSP00000459019.1|ensembl:ENSP00000459419.1|ensembl:ENSP00000483743.2|ensembl:ENSP00000491350.1|ensembl:ENSP00000491393.1|ensembl:ENSP00000492026.2|ensembl:ENSP00000492083.1	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	"psi-mi:pls3_human(display_long)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 3""(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)"	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861105|imex:IM-13779-6594	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838.17(gene)|ensembl:ENSG00000284009.2(gene)|go:""GO:0045340""(mercury ion binding)|ensembl:ENST00000324822.15(transcript)|ensembl:ENST00000574401.5(transcript)|ensembl:ENST00000576201.5(transcript)|ensembl:ENST00000619711.5(transcript)|ensembl:ENST00000639780.1(transcript)|ensembl:ENST00000639874.2(transcript)|ensembl:ENST00000640053.1(transcript)|ensembl:ENST00000640375.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0032049""(cardiolipin biosynthetic process)|go:""GO:0032791""(lead ion binding)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0090199""(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)|mint:Q9NRY6|panther:PTHR23248(orthology-group)"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	intact-crc:4DC96126CADE0919|rigid:BclxqErJ2rjnhAkQs48H9d/5GOg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NRY6	uniprotkb:Q8ZIL5	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021.11|ensembl:ENSP00000459019.1|ensembl:ENSP00000459419.1|ensembl:ENSP00000483743.2|ensembl:ENSP00000491350.1|ensembl:ENSP00000491393.1|ensembl:ENSP00000492026.2|ensembl:ENSP00000492083.1	intact:EBI-2855644|uniprotkb:Q0WJI4	"psi-mi:pls3_human(display_long)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 3""(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)"	psi-mi:cara_yerpe(display_long)|uniprotkb:carA(gene name)|psi-mi:carA(display_short)|uniprotkb:Carbamoyl phosphate synthetase glutamine chain(gene name synonym)|uniprotkb:YPO0481(locus name)|uniprotkb:YP_3698(locus name)|uniprotkb:y3693(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861126|imex:IM-13779-6595	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838.17(gene)|ensembl:ENSG00000284009.2(gene)|go:""GO:0045340""(mercury ion binding)|ensembl:ENST00000324822.15(transcript)|ensembl:ENST00000574401.5(transcript)|ensembl:ENST00000576201.5(transcript)|ensembl:ENST00000619711.5(transcript)|ensembl:ENST00000639780.1(transcript)|ensembl:ENST00000639874.2(transcript)|ensembl:ENST00000640053.1(transcript)|ensembl:ENST00000640375.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0032049""(cardiolipin biosynthetic process)|go:""GO:0032791""(lead ion binding)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0090199""(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)|mint:Q9NRY6|panther:PTHR23248(orthology-group)"	"interpro:IPR029062|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR017926|refseq:WP_002224759.1|interpro:IPR035686|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0004359""(glutaminase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005951""(carbamoyl-phosphate synthase complex)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|interpro:IPR050472|interpro:IPR036480|refseq:YP_002345554.1|panther:PTHR11405(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	rogid:jU7sTbYvJhDasXs9v10lgQwS/IE632	intact-crc:5B3FFD8C73F8AA39|rigid:6GdFW6KpjDLZH1xIuvsFSGnHnDU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NRQ2	uniprotkb:P58497	intact:EBI-769257|uniprotkb:Q2TTR3|uniprotkb:Q658L3|uniprotkb:Q7Z505|uniprotkb:A8K2E9|uniprotkb:Q6ZR73|ensembl:ENSP00000347038.2|ensembl:ENSP00000399315.2|ensembl:ENSP00000419040.1	intact:EBI-2840431|uniprotkb:Q0WHQ6	"psi-mi:pls4_human(display_long)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 4""(gene name synonym)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 43 protein(gene name synonym)|uniprotkb:PLSCR4(gene name)|psi-mi:PLSCR4(display_short)|uniprotkb:GIG43(orf name)"	psi-mi:mode_yerpe(display_long)|uniprotkb:modE(gene name)|psi-mi:modE(display_short)|uniprotkb:YPO1143(locus name)|uniprotkb:y3040(locus name)|uniprotkb:YP_1017(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861091|imex:IM-13779-6593	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005247711.1|refseq:XP_005247712.1|refseq:NP_001121778.1|refseq:NP_001170775.1|refseq:NP_065086.2|refseq:NP_001121776.1|refseq:NP_001121777.1|ensembl:ENSG00000114698.15(gene)|ensembl:ENST00000354952.7(transcript)|ensembl:ENST00000446574.6(transcript)|ensembl:ENST00000493382.5(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0071222""(cellular response to lipopolysaccharide)|interpro:IPR005552(Scramblase)|mint:Q9NRQ2|rcsb pdb:3Q5U|refseq:XP_011511333.1|panther:PTHR23248(orthology-group)"	"interpro:IPR005116(Transport-associated OB, type 1)|interpro:IPR004606(Molybdenum-pterin binding)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR003725(Molybdenum-binding protein, N-terminal)|interpro:IPR016462(Molybdate-dependent transcriptional regulator, ModE)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0015689""(molybdate ion transport)|go:""GO:0030151""(molybdenum ion binding)|refseq:WP_002210754.1|refseq:YP_002346182.1|interpro:IPR036388|interpro:IPR036390|interpro:IPR051815|panther:PTHR30432(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bqEhBoGZZebMZn4JWpg/X0qU49A9606	rogid:UOXc5L3bZSzLOIuq9x/17/AMHmM632	intact-crc:26C2D661C573AF6B|rigid:Oi8GtZamLx8cgz9wLH2p/7h88SQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NRY6	uniprotkb:Q9X6B0	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021.11|ensembl:ENSP00000459019.1|ensembl:ENSP00000459419.1|ensembl:ENSP00000483743.2|ensembl:ENSP00000491350.1|ensembl:ENSP00000491393.1|ensembl:ENSP00000492026.2|ensembl:ENSP00000492083.1	intact:EBI-2844324|intact:EBI-2856296|uniprotkb:Q0WBX3	"psi-mi:pls3_human(display_long)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 3""(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)"	psi-mi:katg_yerpe(display_long)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)|uniprotkb:katY(gene name synonym)|uniprotkb:Antigen 5(gene name synonym)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:YPO3319(locus name)|uniprotkb:y0870(locus name)|uniprotkb:YP_0367(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861119|imex:IM-13779-6598	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838.17(gene)|ensembl:ENSG00000284009.2(gene)|go:""GO:0045340""(mercury ion binding)|ensembl:ENST00000324822.15(transcript)|ensembl:ENST00000574401.5(transcript)|ensembl:ENST00000576201.5(transcript)|ensembl:ENST00000619711.5(transcript)|ensembl:ENST00000639780.1(transcript)|ensembl:ENST00000639874.2(transcript)|ensembl:ENST00000640053.1(transcript)|ensembl:ENST00000640375.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0032049""(cardiolipin biosynthetic process)|go:""GO:0032791""(lead ion binding)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0090199""(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)|mint:Q9NRY6|panther:PTHR23248(orthology-group)"	"interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|go:""GO:0004096""(catalase activity)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|refseq:WP_002209433.1|refseq:YP_002348215.1|panther:PTHR30555(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	rogid:RBebELhpxkVGfQv9Ix9rW4jzmpE632	intact-crc:CD3E18B303D494DC|rigid:ubgOkd3WuMUUORLrVp9A7DEwFhI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NRY6	uniprotkb:A0A0H2W6E9	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021.11|ensembl:ENSP00000459019.1|ensembl:ENSP00000459419.1|ensembl:ENSP00000483743.2|ensembl:ENSP00000491350.1|ensembl:ENSP00000491393.1|ensembl:ENSP00000492026.2|ensembl:ENSP00000492083.1	intact:EBI-2853427|uniprotkb:Q74WL2|uniprotkb:Q74XZ4|uniprotkb:Q74WU0|uniprotkb:Q8CLY1	"psi-mi:pls3_human(display_long)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 3""(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)"	psi-mi:a0a0h2w6e9_yerpe(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861098|imex:IM-13779-6596	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838.17(gene)|ensembl:ENSG00000284009.2(gene)|go:""GO:0045340""(mercury ion binding)|ensembl:ENST00000324822.15(transcript)|ensembl:ENST00000574401.5(transcript)|ensembl:ENST00000576201.5(transcript)|ensembl:ENST00000619711.5(transcript)|ensembl:ENST00000639780.1(transcript)|ensembl:ENST00000639874.2(transcript)|ensembl:ENST00000640053.1(transcript)|ensembl:ENST00000640375.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0032049""(cardiolipin biosynthetic process)|go:""GO:0032791""(lead ion binding)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0090199""(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)|mint:Q9NRY6|panther:PTHR23248(orthology-group)"	"refseq:YP_093918.1|interpro:IPR002686(Transposase IS200-like)|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|interpro:IPR036515"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	rogid:7GOftNTJxtzq5aUbatG8ug5sIa0632	intact-crc:2428ED514DB5380A|rigid:n5pLtn3EBf6Hr62icSqQnHanu+w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ16	uniprotkb:Q9NRY6	intact:EBI-2841852|uniprotkb:Q0WJZ3	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021.11|ensembl:ENSP00000459019.1|ensembl:ENSP00000459419.1|ensembl:ENSP00000483743.2|ensembl:ENSP00000491350.1|ensembl:ENSP00000491393.1|ensembl:ENSP00000492026.2|ensembl:ENSP00000492083.1	psi-mi:lexa_yerpe(display_long)|uniprotkb:lexA(gene name)|psi-mi:lexA(display_short)|uniprotkb:YPO0314(locus name)|uniprotkb:y0572(locus name)|uniprotkb:YP_0470(locus name)	"psi-mi:pls3_human(display_long)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 3""(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861112|imex:IM-13779-6597	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039418|interpro:IPR006199(LexA DNA-binding region)|interpro:IPR006200(Peptidase S24, LexA repressor)|interpro:IPR006197(Peptidase S24, LexA/MucA/RumA/RuvA)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0009432""(SOS response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002345395.1|refseq:WP_002209090.1|interpro:IPR036286|interpro:IPR036388|interpro:IPR036390|interpro:IPR050077|panther:PTHR33516(orthology-group)"	"refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838.17(gene)|ensembl:ENSG00000284009.2(gene)|go:""GO:0045340""(mercury ion binding)|ensembl:ENST00000324822.15(transcript)|ensembl:ENST00000574401.5(transcript)|ensembl:ENST00000576201.5(transcript)|ensembl:ENST00000619711.5(transcript)|ensembl:ENST00000639780.1(transcript)|ensembl:ENST00000639874.2(transcript)|ensembl:ENST00000640053.1(transcript)|ensembl:ENST00000640375.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0032049""(cardiolipin biosynthetic process)|go:""GO:0032791""(lead ion binding)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0090199""(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)|mint:Q9NRY6|panther:PTHR23248(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1RBPmARbsfVEavq4/r0MVDBH/Og632	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	intact-crc:51356E8C730C9387|rigid:T0JPi8WaJ6Iq+Axm6BLmVqIaIW8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ74	uniprotkb:Q9NRY6	intact:EBI-2861133|uniprotkb:Q0WK60	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021.11|ensembl:ENSP00000459019.1|ensembl:ENSP00000459419.1|ensembl:ENSP00000483743.2|ensembl:ENSP00000491350.1|ensembl:ENSP00000491393.1|ensembl:ENSP00000492026.2|ensembl:ENSP00000492083.1	psi-mi:aroe_yerpe(display_long)|uniprotkb:aroE(gene name)|psi-mi:aroE(display_short)|uniprotkb:YPO0246(locus name)|uniprotkb:y4028(locus name)|uniprotkb:YP_0245(locus name)	"psi-mi:pls3_human(display_long)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 3""(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861138|imex:IM-13779-6599	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011342(Quinate/shikimate 5-dehydrogenase)|interpro:IPR013708(Shikimate dehydrogenase substrate binding, N-terminal)|interpro:IPR022893|interpro:IPR006151(Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase)|refseq:WP_002209026.1|go:""GO:0004764""(""shikimate 3-dehydrogenase (NADP+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0009073""(aromatic amino acid family biosynthetic process)|go:""GO:0009423""(chorismate biosynthetic process)|go:""GO:0019632""(shikimate metabolic process)|go:""GO:0050661""(NADP binding)|interpro:IPR036291|interpro:IPR041121|refseq:YP_002345328.1|interpro:IPR046346|panther:PTHR21089(orthology-group)"	"refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838.17(gene)|ensembl:ENSG00000284009.2(gene)|go:""GO:0045340""(mercury ion binding)|ensembl:ENST00000324822.15(transcript)|ensembl:ENST00000574401.5(transcript)|ensembl:ENST00000576201.5(transcript)|ensembl:ENST00000619711.5(transcript)|ensembl:ENST00000639780.1(transcript)|ensembl:ENST00000639874.2(transcript)|ensembl:ENST00000640053.1(transcript)|ensembl:ENST00000640375.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0032049""(cardiolipin biosynthetic process)|go:""GO:0032791""(lead ion binding)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0090199""(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)|mint:Q9NRY6|panther:PTHR23248(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dRYrxoQeMbXrptePRIuZexxnfl8632	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	intact-crc:CC136E8C73B4A776|rigid:iCfRBZUMixzwhyLGGCzaL+91tRo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZQ9	uniprotkb:O15162	intact:EBI-2852846|uniprotkb:Q74RW8	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	psi-mi:q8czq9_yerpe(display_long)|uniprotkb:y3602(locus name)|uniprotkb:exuR(gene name)|psi-mi:exuR(display_short)|uniprotkb:YP_2896(locus name)	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861145|imex:IM-13779-6601	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011711(GntR, C-terminal)|interpro:IPR000524(Bacterial regulatory protein GntR, HTH)|interpro:IPR008920(Fatty acid responsive transcription factor FadR, C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RD2sxgq5tm9YnJVsIx4EdMD3/Uw632	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	intact-crc:3075F72285BE7F02|rigid:SOxN82KDcdBLPYVfjnvGeJisJS8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15162	uniprotkb:Q7ARD3	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861159|imex:IM-13779-6600	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:080A713958E49829|rigid:/btBPqYlTxYzcDo+OO4+N4+vmX0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15162	uniprotkb:Q7CGI0	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	intact:EBI-2840021|uniprotkb:Q74RN4	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	psi-mi:ftsp_yerpe(display_long)|uniprotkb:ftsP(gene name)|psi-mi:ftsP(display_short)|uniprotkb:YPO0673(locus name)|uniprotkb:YP_2989(locus name)|uniprotkb:y3504(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861152|imex:IM-13779-6602	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	"refseq:YP_002345741.1|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR008972(Cupredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR026589|refseq:WP_002212176.1|go:""GO:0005507""(copper ion binding)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|interpro:IPR045087|panther:PTHR11709(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:JQTwQ8R/Yza07pQepCvAhD8UkWA632	intact-crc:DFE96EDB580255BB|rigid:RdUqmUM7BO4iGYV3QnJI8W6d3rY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4AWI2	uniprotkb:P00747	intact:EBI-2850800|uniprotkb:Q74PQ4|uniprotkb:Q0WB69|uniprotkb:Q7CL85|uniprotkb:A0A384LA61	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	psi-mi:a0a3n4awi2_yerpe(display_long)|uniprotkb:ntrA(gene name synonym)|uniprotkb:rpoN(gene name synonym)|uniprotkb:YPO3582(locus name)|uniprotkb:glnF(gene name)|psi-mi:glnF(display_short)	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861180|imex:IM-13779-6604	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000394(RNA polymerase sigma factor 54)|interpro:IPR007046(RNA polymerase sigma factor 54, core-binding)|interpro:IPR007634(RNA polymerase sigma factor 54, DNA-binding)|refseq:WP_002210115.1|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001216""(DNA-binding transcription activator activity)|go:""GO:0003677""(DNA binding)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0016987""(sigma factor activity)|interpro:IPR038709|refseq:YP_002348469.1|panther:PTHR32248(orthology-group)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zdzEhy+OLn0kaYS9XKuSOj5MMBM632	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	intact-crc:01E81C42481A7E57|rigid:wbnnPB2YvRy0Fs0ZYOeghSUK71c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1A4	uniprotkb:Q9NYY3	intact:EBI-2850994	intact:EBI-721354|uniprotkb:O60679|uniprotkb:Q96CV7|uniprotkb:Q9UE61|ensembl:ENSP00000274289.3	psi-mi:q8d1a4_yerpe(display_long)|uniprotkb:y0798(locus name)|uniprotkb:fhuB(gene name)|psi-mi:fhuB(display_short)	psi-mi:plk2_human(display_long)|uniprotkb:Polo-like kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SNK(gene name synonym)|uniprotkb:Serum-inducible kinase(gene name synonym)|uniprotkb:PLK2(gene name)|psi-mi:PLK2(display_short)|uniprotkb:SNK(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861194|imex:IM-13779-6605	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000522(Bacterial transport system permease protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR037294"	"dip:DIP-48943N|refseq:NP_006613.2|refseq:NP_001239155.1|ensembl:ENSG00000145632.15(gene)|ensembl:ENST00000274289.8(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0000922""(spindle pole)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007613""(memory)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032486""(Rap protein signal transduction)|go:""GO:0043008""(ATP-dependent protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0060292""(long-term synaptic depression)|go:""GO:0071866""(negative regulation of apoptotic process in bone marrow cell)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:2000773""(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|interpro:IPR042825|mint:Q9NYY3|rcsb pdb:4I5M|rcsb pdb:4I5P|rcsb pdb:4I6B|rcsb pdb:4I6F|rcsb pdb:4I6H|rcsb pdb:4RS6|rcsb pdb:4XB0|reactome:R-HSA-6804115|reactome:R-HSA-9662834|reactome:R-HSA-9768919|panther:PTHR24345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PGAfc4VH09eJJH0aF+uMggT6rQg632	rogid:pjEqMnSG5E6daeauZylX38gmiS09606	intact-crc:04B746B55576955C|rigid:sM3tsIQCRZruLHZdFCDu0Q/YYLA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00747	uniprotkb:Q7CGB6	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938.9	intact:EBI-2846518|uniprotkb:Q74Q78	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:seca_yerpe(display_long)|uniprotkb:secA(gene name)|psi-mi:secA(display_short)|uniprotkb:YPO0564(locus name)|uniprotkb:y3617(locus name)|uniprotkb:YP_3620(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861187|imex:IM-13779-6607	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:537072""|efo:""Orphanet:722""|ensembl:ENSG00000122194.20(gene)|ensembl:ENST00000308192.14(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007596""(blood coagulation)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0051919""(positive regulation of fibrinolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990405""(protein antigen binding)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|rcsb pdb:7E50|rcsb pdb:7THS|rcsb pdb:7UAH|rcsb pdb:8F7U|rcsb pdb:8F7V|rcsb pdb:8UQ6|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|refseq:NP_000292.1|panther:PTHR24261(orthology-group)"	"interpro:IPR004027(SEC-C motif)|interpro:IPR000185(SecA protein)|interpro:IPR020937|interpro:IPR011115(SecA DEAD-like)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR044722|interpro:IPR027417|refseq:WP_002210426.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0017038""(protein import)|go:""GO:0031522""(cell envelope Sec protein transport complex)|go:""GO:0043952""(protein transport by the Sec complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0065002""(intracellular protein transmembrane transport)|interpro:IPR036266|interpro:IPR036670|refseq:YP_002345635.1|panther:PTHR30612(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:3yL6/B2I1wIRUb5RFvMibkWeWlQ632	intact-crc:32DDC25FE8D1F906|rigid:5zx+pEivWFtriQ9rm/hYZXjcOH0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43660	uniprotkb:Q0WBF9	intact:EBI-1051504|uniprotkb:Q3KQY5|uniprotkb:Q8WUD8|uniprotkb:B3KMK4|ensembl:ENSP00000424417.1	intact:EBI-2856682|uniprotkb:Q74X66|uniprotkb:Q8D1D1	psi-mi:plrg1_human(display_long)|uniprotkb:PLRG1(gene name)|psi-mi:PLRG1(display_short)	psi-mi:pnp_yerpe(display_long)|uniprotkb:pnp(gene name)|psi-mi:pnp(display_short)|uniprotkb:Polynucleotide phosphorylase(gene name synonym)|uniprotkb:YPO3490(locus name)|uniprotkb:y0694(locus name)|uniprotkb:YP_0593(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861166|imex:IM-13779-6603	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188493.1|refseq:NP_002660.1|ensembl:ENSG00000171566.12(gene)|ensembl:ENST00000499023.7(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000974""(Prp19 complex)|go:""GO:0001650""(fibrillar center)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR045241|mint:O43660|rcsb pdb:4YVD|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DH6|rcsb pdb:7DVQ|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8RO2|rcsb pdb:9FMD|reactome:R-HSA-72163|panther:PTHR19923(orthology-group)"	"refseq:WP_002209259.1|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR020568|interpro:IPR027408|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004654""(polyribonucleotide nucleotidyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0006401""(RNA catabolic process)|go:""GO:0006402""(mRNA catabolic process)|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612|refseq:YP_002348379.1|panther:PTHR11252(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TdZ60+R9eEw7Q0zgsHjv8DImHMA9606	rogid:OtyeeLgdrKybDBd4sPZ7s/ufy78632	intact-crc:AA83491A38170A51|rigid:/f7jqoN2dBUrICbotO2Iq8L1oEI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O68779	uniprotkb:Q04941	intact:EBI-2853455|intact:EBI-2855635|uniprotkb:Q74YF2|uniprotkb:Q7ARB0|uniprotkb:Q7BT13|uniprotkb:A0A3G5L6V4|uniprotkb:A0A1U8QYA4|uniprotkb:A0A0H2W5L4|uniprotkb:Q7CIE2	intact:EBI-608347|uniprotkb:A6NDT7|uniprotkb:Q32MM8|ensembl:ENSP00000365505.5	psi-mi:o68779_yerpe(display_long)|uniprotkb:y1062(gene name)|psi-mi:y1062(display_short)|uniprotkb:ypmt1.80C(gene name synonym)|uniprotkb:ISU59_11670(orf name)|uniprotkb:ISU59_12615(orf name)|uniprotkb:YPMT1.80c(locus name)|uniprotkb:YPO0011(locus name)|uniprotkb:YPO1493(locus name)|uniprotkb:YPO1561(locus name)|uniprotkb:YPO1583(locus name)|uniprotkb:YPO1589(locus name)|uniprotkb:YPO1621(locus name)|uniprotkb:YPO1727(locus name)|uniprotkb:YPO1988(locus name)|uniprotkb:YPO2104(locus name)|uniprotkb:YPO2136(locus name)|uniprotkb:YPO2170(locus name)|uniprotkb:YPO2194(locus name)|uniprotkb:YPO2447(locus name)|uniprotkb:YPO2571(locus name)|uniprotkb:YPO2656(locus name)|uniprotkb:YPO2783(locus name)|uniprotkb:YPO2799(locus name)|uniprotkb:YPO2862(locus name)|uniprotkb:YPO2942(locus name)|uniprotkb:YPO3875(locus name)	psi-mi:plp2_human(display_long)|uniprotkb:Intestinal membrane A4 protein(gene name synonym)|uniprotkb:Differentiation-dependent protein A4(gene name synonym)|uniprotkb:PLP2(gene name)|psi-mi:PLP2(display_short)|uniprotkb:A4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861173|imex:IM-13779-6606	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395426.1|refseq:NP_857700.1|interpro:IPR001207(Transposase, mutator type)|refseq:YP_093966.1|refseq:WP_002209743.1|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|refseq:YP_002347531.1|refseq:YP_002345107.1|refseq:YP_002346509.1|refseq:YP_002346575.1|refseq:YP_002346595.1|refseq:YP_002346600.1|refseq:YP_002346632.1|refseq:YP_002346729.1|refseq:YP_002346973.1|refseq:YP_002347085.1|refseq:YP_002347114.1|refseq:YP_002347145.1|refseq:YP_002347167.1|refseq:YP_002347411.1|refseq:YP_002347607.1|refseq:YP_002347730.1|refseq:YP_002347741.1|refseq:YP_002347797.1|refseq:YP_002347869.1|refseq:YP_002348751.1|panther:PTHR33217(orthology-group)"	"ensembl:ENSG00000102007.11(gene)|ensembl:ENST00000376327.6(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006935""(chemotaxis)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019956""(chemokine binding)|interpro:IPR008253(Marvel)|interpro:IPR050578|mint:Q04941|refseq:NP_002659.1|panther:PTHR22776(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y/++sl3PEsvjk5YqmX2+hc+8JHM632	rogid:mQOlRVDVw9W4XWAzftif1tnKEdU9606	intact-crc:2D469B2661D78A43|rigid:UzunijDAGgUSSEo9HvN2NTzvxic	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3V8I0	uniprotkb:Q6DJT9	intact:EBI-2858430	intact:EBI-1220878|uniprotkb:Q59GH8|uniprotkb:Q9Y4L2|uniprotkb:B4DLC2|ensembl:ENSP00000325546.3|ensembl:ENSP00000416537.2	psi-mi:a0a6b3v8i0_yerpe(display_long)|uniprotkb:y3432(locus name)	psi-mi:plag1_human(display_long)|uniprotkb:PLAG1(gene name)|psi-mi:PLAG1(display_short)|uniprotkb:Pleiomorphic adenoma gene 1 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861214|imex:IM-13779-6608	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A6B3T871(uniprot-removed-ac)|interpro:IPR031325|interpro:IPR001826(RHS protein)|interpro:IPR006530(YD repeat)|interpro:IPR022385|interpro:IPR050708|interpro:IPR045351|refseq:WP_002223678.1	"efo:""Orphanet:397590""|efo:""Orphanet:454821""|ensembl:ENSG00000181690.8(gene)|ensembl:ENST00000316981.8(transcript)|ensembl:ENST00000429357.2(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016607""(nuclear speck)|go:""GO:0022612""(gland morphogenesis)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060736""(prostate gland growth)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q6DJT9|refseq:NP_001108106.1|refseq:NP_001108107.1|refseq:NP_002646.2|refseq:XP_011515846.1|refseq:XP_016869065.1|refseq:XP_016869066.1|panther:PTHR24388(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:15j6ruoytaqTYCE9CNBDSnL94j8632	rogid:u1dG94SRn9oUw9PPm0nlcfS1jQY9606	intact-crc:C2A48FA7C80942EA|rigid:s3K3zGcPmGYEZLF7oaQWwhyWP9c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H7P9	uniprotkb:A0A380PL37	intact:EBI-2797213|ensembl:ENSP00000392906.2|uniprotkb:Q9H699|uniprotkb:Q6DHV6|uniprotkb:Q96BU2|uniprotkb:B8ZZK6|uniprotkb:Q96D18|uniprotkb:C9J0Y4	intact:EBI-2848428|uniprotkb:Q74PX4|uniprotkb:A0A0H2W7W6|uniprotkb:Q7CG52|uniprotkb:A0A384KFS5	psi-mi:pkhg2_human(display_long)|uniprotkb:PLEKHG2(gene name)|psi-mi:PLEKHG2(display_short)	psi-mi:a0a380pl37_yerpe(display_long)|uniprotkb:YPO0421(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861240|imex:IM-13779-6610	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090924.15(gene)|ensembl:ENST00000425673.6(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0031267""(small GTPase binding)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR043324|interpro:IPR055251|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_073746.2|refseq:XP_005259220.1|panther:PTHR45924(orthology-group)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR027463|refseq:WP_002209200.1|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:YP_002345497.1|panther:PTHR32063(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mltTLBwRpTza8JTKuQjBZpSol/M9606	rogid:eNynpfVNIWDaaydEc5eAanQErH8632	intact-crc:3F78EA7452C58A2A|rigid:8sSpTY8/lcyChmSCLMkADAOJhVc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IVE3	uniprotkb:Q7ARD3	intact:EBI-2815745|uniprotkb:Q6P4Q1|uniprotkb:Q8N3Q3|uniprotkb:Q5JPJ6|ensembl:ENSP00000282406.4	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:pkhh2_human(display_long)|uniprotkb:PLEKHH2(gene name)|psi-mi:PLEKHH2(display_short)|uniprotkb:KIAA2028(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861233|imex:IM-13779-6609	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_742066.2|ensembl:ENSG00000152527.14(gene)|ensembl:ENST00000282406.9(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0030027""(lamellipodium)|go:""GO:0030835""(negative regulation of actin filament depolymerization)|go:""GO:0030864""(cortical actin cytoskeleton)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR038185|refseq:XP_016858842.1|panther:PTHR22903(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vIFW/bsu7BKuWZYe+VyQpQBdYnQ9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:2C23517BDDFF087B|rigid:QAUMgQuNc7ugm9ucDKtSKyGKI0E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCU2	uniprotkb:Q53GL0	intact:EBI-2861221|uniprotkb:Q0WD31	intact:EBI-949945|uniprotkb:Q336K5|uniprotkb:Q8IZ51|uniprotkb:Q9UL48|uniprotkb:Q9NRV3|ensembl:ENSP00000358120.4	psi-mi:ex7l_yerpe(display_long)|uniprotkb:xseA(gene name)|psi-mi:xseA(display_short)|uniprotkb:Exodeoxyribonuclease VII large subunit(gene name synonym)|uniprotkb:YPO2872(locus name)|uniprotkb:y1361(locus name)|uniprotkb:YP_2738(locus name)	psi-mi:pkho1_human(display_long)|uniprotkb:HQ0024c(orf name)|uniprotkb:PLEKHO1(gene name)|psi-mi:PLEKHO1(display_short)|uniprotkb:CKIP1(gene name synonym)|uniprotkb:Casein kinase 2-interacting protein 1(gene name synonym)|uniprotkb:Osteoclast maturation-associated gene 120 protein(gene name synonym)|uniprotkb:C-Jun-binding protein(gene name synonym)|uniprotkb:OC120(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861226|imex:IM-13779-6611	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020579|interpro:IPR003753(Exonuclease VII, large subunit)|interpro:IPR025824|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006308""(DNA catabolic process)|go:""GO:0008855""(exodeoxyribonuclease VII activity)|go:""GO:0009318""(exodeoxyribonuclease VII complex)|refseq:WP_002209810.1|refseq:YP_002347807.1|panther:PTHR30008(orthology-group)"	"refseq:NP_057358.2|refseq:NP_001291651.1|refseq:NP_001291652.1|refseq:NP_001291653.1|refseq:XP_016856909.1|dip:DIP-46903N|ensembl:ENSG00000023902.14(gene)|ensembl:ENST00000369124.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0032587""(ruffle membrane)|go:""GO:0036195""(muscle cell projection membrane)|go:""GO:0051451""(myoblast migration)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1901739""(regulation of myoblast fusion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR043448|mint:Q53GL0|rcsb pdb:3AA1|panther:PTHR15871(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zU89dTJy0spohd+cw3CGxfreDmk632	rogid:f+fuKzDy9VwrKcC9fJMo3JqRenM9606	intact-crc:71C573FFC1888052|rigid:scU5z8sWeKrkppbCsFztqvMO7vI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6P4A8	uniprotkb:Q8D1P6	intact:EBI-2861204|uniprotkb:Q9BVV3|uniprotkb:Q9H625|uniprotkb:A8K4E9|ensembl:ENSP00000240617.5	intact:EBI-2839854	psi-mi:plbl1_human(display_long)|uniprotkb:PLBD1(gene name)|psi-mi:PLBD1(display_short)|uniprotkb:LAMA-like protein 1(gene name synonym)|uniprotkb:Lamina ancestor homolog 1(gene name synonym)|uniprotkb:Phospholipase B domain-containing protein 1(gene name synonym)	psi-mi:q8d1p6_yerpe(display_long)|uniprotkb:tcaC1(gene name)|psi-mi:tcaC1(display_short)|uniprotkb:y0185(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861201|imex:IM-13779-6612	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079105.4|ensembl:ENSG00000121316.11(gene)|ensembl:ENST00000240617.10(transcript)|go:""GO:0004620""(phospholipase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005829""(cytosol)|go:""GO:0009395""(phospholipid catabolic process)|interpro:IPR007000(Laminin A)|interpro:IPR043040|interpro:IPR043041|interpro:IPR043042|mint:Q6P4A8|reactome:R-HSA-1482788|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1483115|panther:PTHR12370(orthology-group)"	"interpro:IPR003284(Salmonella virulence plasmid 65kDa B protein)|interpro:IPR022044|interpro:IPR022045|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|interpro:IPR028994"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6ZbYKlwkiOBkyp3kckZ4QkLCj689606	rogid:O/TCvNvvMc3GrD6oFI13BOD7NL8632	intact-crc:8D635CE1176C5393|rigid:S2zlxi7Qa0m6rXTFEoiynKeR7vI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D054	uniprotkb:O43164	intact:EBI-2852052	intact:EBI-1996038|uniprotkb:D3DSZ5|ensembl:ENSP00000354775.2|ensembl:ENSP00000355284.3|uniprotkb:Q68D49|uniprotkb:Q8N1G5|uniprotkb:A8K6U4	psi-mi:q8d054_yerpe(display_long)|uniprotkb:fabF(gene name)|psi-mi:fabF(display_short)|uniprotkb:fabF_4(gene name synonym)|uniprotkb:NCTC5923_01694(orf name)|uniprotkb:y2744(locus name)	psi-mi:pja2_human(display_long)|uniprotkb:PJA2(gene name)|psi-mi:PJA2(display_short)|uniprotkb:KIAA0438(gene name synonym)|uniprotkb:RNF131(gene name synonym)|uniprotkb:RING finger protein 131(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Praja-2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861261|imex:IM-13779-6614	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018201|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016039(Thiolase-like)|interpro:IPR020841|go:""GO:0004315""(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:""GO:0006633""(fatty acid biosynthetic process)|interpro:IPR000794(Beta-ketoacyl synthase)"	"ensembl:ENSG00000198961.10(gene)|ensembl:ENST00000361189.7(transcript)|ensembl:ENST00000361557.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0007616""(long-term memory)|go:""GO:0010738""(regulation of protein kinase A signaling)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0034137""(positive regulation of toll-like receptor 2 signaling pathway)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900745""(positive regulation of p38MAPK cascade)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O43164|reactome:R-HSA-983168|refseq:NP_055634.3|panther:PTHR15710(orthology-group)|refseq:XP_016865588.1|dip:DIP-47040N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:Xl43YLev9BwgHiphq3Wzri47FxA632	rogid:z0OkXLozXymqwyF+xQR+PFa+bQI9606	intact-crc:B901289A7E5D0EAB|rigid:37E1I06CFwlPBEHxc+3KdBF1mJk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HB21	uniprotkb:Q8ZC32	intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986.3|ensembl:ENSP00000376547.3|ensembl:ENSP00000394416.1	intact:EBI-2852171|uniprotkb:Q0WC91	psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym)	psi-mi:quea_yerpe(display_long)|uniprotkb:queA(gene name)|psi-mi:queA(display_short)|uniprotkb:Queuosine biosynthesis protein QueA(gene name synonym)|uniprotkb:YPO3192(locus name)|uniprotkb:y0990(locus name)|uniprotkb:YP_0739(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861247|imex:IM-13779-6613	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:XP_005270073.1|refseq:XP_005270078.1|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679.15(gene)|ensembl:ENST00000368990.8(transcript)|ensembl:ENST00000392799.7(transcript)|ensembl:ENST00000433307.2(transcript)|go:""GO:0001553""(luteinization)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008209""(androgen metabolic process)|go:""GO:0008210""(estrogen metabolic process)|go:""GO:0009791""(post-embryonic development)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0031529""(ruffle organization)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033327""(Leydig cell differentiation)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0043325""(phosphatidylinositol-3,4-bisphosphate binding)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060021""(roof of mouth development)|go:""GO:0060325""(face morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070301""(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR051707|mint:Q9HB21|rcsb pdb:1EAZ|reactome:R-HSA-1660499|panther:PTHR14336(orthology-group)"	"interpro:IPR003699(Queuosine biosynthesis protein)|refseq:WP_002208673.1|go:""GO:0002099""(tRNA wobble guanine modification)|go:""GO:0005737""(cytoplasm)|go:""GO:0008616""(queuosine biosynthetic process)|go:""GO:0051075""(""S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"")|interpro:IPR036100|interpro:IPR042118|interpro:IPR042119|refseq:YP_002348097.1|panther:PTHR30307(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606	rogid:F+PRsjhaH3dz6Fk0kbG+UQpfEYY632	intact-crc:0131DB9B8E85A0EB|rigid:4HAW//JFYQHgYF4PZwZe6TlrSyY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZGW9	uniprotkb:O00562	intact:EBI-2856781|uniprotkb:Q0WHP5	intact:EBI-2861268|uniprotkb:A6NME4|uniprotkb:Q8TBN3|uniprotkb:Q6T7X3|uniprotkb:Q9BZ73|ensembl:ENSP00000348772.3|ensembl:ENSP00000437286.1	psi-mi:biod1_yerpe(display_long)|uniprotkb:Dethiobiotin synthase 1(gene name synonym)|uniprotkb:bioD1(gene name)|psi-mi:bioD1(display_short)|uniprotkb:DTB synthetase 1(gene name synonym)|uniprotkb:YPO1154(locus name)|uniprotkb:y3028(locus name)|uniprotkb:YP_1006(locus name)	psi-mi:pitm1_human(display_long)|uniprotkb:PITPNM1(gene name)|psi-mi:PITPNM1(display_short)|uniprotkb:DRES9(gene name synonym)|uniprotkb:NIR2(gene name synonym)|uniprotkb:PITPNM(gene name synonym)|uniprotkb:Drosophila retinal degeneration B homolog(gene name synonym)|uniprotkb:Phosphatidylinositol transfer protein, membrane-associated 1(gene name synonym)|uniprotkb:Pyk2 N-terminal domain-interacting receptor 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861277|imex:IM-13779-6615	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004472(Dethiobiotin synthase)|interpro:IPR027417|refseq:WP_002216554.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004141""(dethiobiotin synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009102""(biotin biosynthetic process)|refseq:YP_002346193.1|panther:PTHR43210(orthology-group)"	"refseq:NP_001124320.1|refseq:NP_004901.2|refseq:XP_016874075.1|ensembl:ENSG00000110697.14(gene)|ensembl:ENST00000356404.8(transcript)|ensembl:ENST00000534749.5(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0007420""(brain development)|go:""GO:0007602""(phototransduction)|go:""GO:0008525""(phosphatidylcholine transporter activity)|go:""GO:0008526""(phosphatidylinositol transfer activity)|go:""GO:0015031""(protein transport)|go:""GO:0015914""(phospholipid transport)|go:""GO:0016020""(membrane)|go:""GO:0030496""(midbody)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044297""(cell body)|go:""GO:0070300""(phosphatidic acid binding)|interpro:IPR001666(Phosphatidylinositol transfer protein)|interpro:IPR004177(DDHD)|interpro:IPR023214|interpro:IPR023393|interpro:IPR031315|interpro:IPR036412|interpro:IPR055261|mint:O00562|reactome:R-HSA-1483226|panther:PTHR10658(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qYf9r2/zbn9T1FkMmuqRTeKSAp8632	rogid:lJDwa5NR0oz6zQCNbw8fUbVuU0E9606	intact-crc:1005BA05BF4F2B39|rigid:bZZeu2mr/21KV6uosCSKBeVFzj4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BXM7	uniprotkb:Q8ZC51	intact:EBI-2846068|uniprotkb:Q8N6T9|uniprotkb:Q8NBU3|uniprotkb:Q96DE4|ensembl:ENSP00000364204.3	intact:EBI-2843370|uniprotkb:Q0WCB2	psi-mi:pink1_human(display_long)|uniprotkb:PINK1(gene name)|psi-mi:PINK1(display_short)|uniprotkb:BRPK(gene name synonym)|uniprotkb:PTEN-induced putative kinase protein 1(gene name synonym)	psi-mi:pane_yerpe(display_long)|uniprotkb:panE(gene name)|psi-mi:panE(display_short)|uniprotkb:apbA(gene name synonym)|uniprotkb:Ketopantoate reductase(gene name synonym)|uniprotkb:YPO3171(locus name)|uniprotkb:y1014(locus name)|uniprotkb:YP_0760(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861284|imex:IM-13779-6617	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000158828.8(gene)|ensembl:ENST00000321556.5(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0000423""(mitophagy)|go:""GO:0000785""(chromatin)|go:""GO:0002020""(protease binding)|go:""GO:0002082""(regulation of oxidative phosphorylation)|go:""GO:0002931""(response to ischemia)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0014046""(dopamine secretion)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0016301""(kinase activity)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030424""(axon)|go:""GO:0030426""(growth cone)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032148""(activation of protein kinase B activity)|go:""GO:0032226""(positive regulation of synaptic transmission, dopaminergic)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033603""(positive regulation of dopamine secretion)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0038203""(TORC2 signaling)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043422""(protein kinase B binding)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051443""(positive regulation of ubiquitin-protein transferase activity)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055131""(C3HC4-type RING finger domain binding)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0072655""(establishment of protein localization to mitochondrion)|go:""GO:0072656""(maintenance of protein location in mitochondrion)|go:""GO:0090141""(positive regulation of mitochondrial fission)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0090258""(negative regulation of mitochondrial fission)|go:""GO:0097237""(cellular response to toxic substance)|go:""GO:0097413""(Lewy body)|go:""GO:0097449""(astrocyte projection)|go:""GO:0099074""(mitochondrion to lysosome vesicle-mediated transport)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900407""(regulation of cellular response to oxidative stress)|go:""GO:1901525""(negative regulation of mitophagy)|go:""GO:1902803""(regulation of synaptic vesicle transport)|go:""GO:1902902""(negative regulation of autophagosome assembly)|go:""GO:1902958""(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|go:""GO:1903298""(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:""GO:1903377""(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:""GO:1903384""(negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway)|go:""GO:1903751""(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:1903852""(positive regulation of cristae formation)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:1904544""(positive regulation of free ubiquitin chain polymerization)|go:""GO:1904841""(TORC2 complex binding)|go:""GO:1904881""(cellular response to hydrogen sulfide)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000377""(regulation of reactive oxygen species metabolic process)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2001171""(positive regulation of ATP biosynthetic process)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR040110|interpro:IPR051511|mint:Q9BXM7|reactome:R-HSA-5205685|reactome:R-HSA-9614657|refseq:NP_115785.1|dip:DIP-29427N|efo:""Orphanet:2828""|panther:PTHR22972(orthology-group)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR003710(Ketopantoate reductase ApbA/PanE)|interpro:IPR013752(Ketopantoate reductase ApbA/PanE, C-terminal)|interpro:IPR013332(Ketopantoate reductase ApbA/PanE, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|go:""GO:0005737""(cytoplasm)|go:""GO:0008677""(2-dehydropantoate 2-reductase activity)|go:""GO:0015940""(pantothenate biosynthetic process)|go:""GO:0050661""(NADP binding)|refseq:WP_002208656.1|interpro:IPR036291|refseq:YP_002348076.1|interpro:IPR050838|panther:PTHR43765(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PL0FnTaDke9w5FQlThTKmye/phs9606	rogid:VMeNwiEEs+L7pYXqwMTUHVm2nxQ632	intact-crc:2155BE66BEFBCE8C|rigid:DUbIqNzW2O09Qhb2wDS6VusolAs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48736	uniprotkb:A0A3G5LJH8	intact:EBI-1030384|uniprotkb:Q8IV23|uniprotkb:Q9BZC8|uniprotkb:A4D0Q6|ensembl:ENSP00000352121.3|ensembl:ENSP00000392258.2|ensembl:ENSP00000419260.1	intact:EBI-2851477|uniprotkb:Q74YN1|uniprotkb:Q7ARE0|uniprotkb:Q7BT25|uniprotkb:A0A384KBQ0|uniprotkb:Q65AN4|uniprotkb:A0A1U8QEQ2|uniprotkb:A0A2U2H125|uniprotkb:O68752	psi-mi:pk3cg_human(display_long)|uniprotkb:PIK3CG(gene name)|psi-mi:PIK3CG(display_short)|uniprotkb:p120-PI3K(gene name synonym)|uniprotkb:Phosphoinositide-3-kinase catalytic gamma polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CG(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma(gene name synonym)	psi-mi:a0a3g5ljh8_yerpe(display_long)|uniprotkb:YPMT1.34(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861254|imex:IM-13779-6616	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002640.2|refseq:NP_001269355.1|refseq:NP_001269356.1|refseq:XP_005250500.1|dip:DIP-37781N|rcsb pdb:3APD|rcsb pdb:3APF|rcsb pdb:3CSF|rcsb pdb:3CST|rcsb pdb:3DBS|ensembl:ENSG00000105851.11(gene)|ensembl:ENST00000359195.3(transcript)|ensembl:ENST00000440650.6(transcript)|ensembl:ENST00000496166.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001819""(positive regulation of cytokine production)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002407""(dendritic cell chemotaxis)|go:""GO:0002675""(positive regulation of acute inflammatory response)|go:""GO:0002679""(respiratory burst involved in defense response)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005943""(phosphatidylinositol 3-kinase complex, class IA)|go:""GO:0005944""(phosphatidylinositol 3-kinase complex, class IB)|go:""GO:0006897""(endocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007200""(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010818""(T cell chemotaxis)|go:""GO:0010897""(negative regulation of triglyceride catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016303""(1-phosphatidylinositol-3-kinase activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0032252""(secretory granule localization)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035005""(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035747""(natural killer cell chemotaxis)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036092""(phosphatidylinositol-3-phosphate biosynthetic process)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043303""(mast cell degranulation)|go:""GO:0043406""(positive regulation of MAP kinase activity)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045087""(innate immune response)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0046934""(1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:""GO:0048015""(phosphatidylinositol-mediated signaling)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055118""(negative regulation of cardiac muscle contraction)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|rcsb pdb:3DPD|go:""GO:0072672""(neutrophil extravasation)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1903169""(regulation of calcium ion transmembrane transport)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000270""(negative regulation of fibroblast apoptotic process)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|interpro:IPR045580|mint:P48736|rcsb pdb:1E8Y|rcsb pdb:1E8Z|rcsb pdb:1HE8|rcsb pdb:2A4Z|rcsb pdb:2A5U|rcsb pdb:2CHW|rcsb pdb:2CHX|rcsb pdb:2CHZ|rcsb pdb:2V4L|rcsb pdb:3APC|rcsb pdb:3ENE|rcsb pdb:3IBE|rcsb pdb:3L08|rcsb pdb:3L13|rcsb pdb:3L16|rcsb pdb:3L17|rcsb pdb:3L54|rcsb pdb:3LJ3|rcsb pdb:3MJW|rcsb pdb:3ML8|rcsb pdb:3ML9|rcsb pdb:3NZS|rcsb pdb:3NZU|rcsb pdb:3OAW|rcsb pdb:3P2B|rcsb pdb:3PRE|rcsb pdb:3PRZ|rcsb pdb:3PS6|rcsb pdb:3QAQ|rcsb pdb:3QAR|rcsb pdb:3QJZ|rcsb pdb:3QK0|rcsb pdb:3R7Q|rcsb pdb:3R7R|rcsb pdb:3S2A|rcsb pdb:3SD5|rcsb pdb:3T8M|rcsb pdb:3TJP|rcsb pdb:3TL5|rcsb pdb:3ZVV|rcsb pdb:3ZW3|rcsb pdb:4ANU|rcsb pdb:4ANV|rcsb pdb:4ANW|rcsb pdb:4ANX|rcsb pdb:4AOF|rcsb pdb:4DK5|rcsb pdb:4EZJ|rcsb pdb:4EZK|rcsb pdb:4EZL|rcsb pdb:4F1S|rcsb pdb:4FA6|rcsb pdb:4FAD|rcsb pdb:4FHJ|rcsb pdb:4FHK|rcsb pdb:4HLE|rcsb pdb:4FJY|rcsb pdb:4FJZ|rcsb pdb:4HVB|rcsb pdb:4FLH|rcsb pdb:4FUL|rcsb pdb:4G11|rcsb pdb:4GB9|rcsb pdb:4J6I|rcsb pdb:4KZ0|rcsb pdb:4KZC|rcsb pdb:4PS3|rcsb pdb:4PS7|rcsb pdb:4PS8|rcsb pdb:4URK|rcsb pdb:4WWN|rcsb pdb:4WWO|rcsb pdb:4WWP|rcsb pdb:4XX5|rcsb pdb:4XZ4|rcsb pdb:5G55|rcsb pdb:5EDS|rcsb pdb:5G2N|rcsb pdb:5JHA|rcsb pdb:5JHB|rcsb pdb:5KAE|rcsb pdb:5OQ4|rcsb pdb:5T23|rcsb pdb:6AUD|rcsb pdb:6C1S|rcsb pdb:6FH5|rcsb pdb:6GQ7|rcsb pdb:6T3B|rcsb pdb:6T3C|rcsb pdb:6XRL|rcsb pdb:6XRM|rcsb pdb:6XRN|rcsb pdb:7JWE|rcsb pdb:7JWZ|rcsb pdb:7JX0|rcsb pdb:7KKE|rcsb pdb:7MEZ|rcsb pdb:7Z61|rcsb pdb:8DP0|rcsb pdb:8SC8|reactome:R-HSA-114604|reactome:R-HSA-1660499|reactome:R-HSA-392451|reactome:R-HSA-9027276|ensembl:ENSP00000352121.3|ensembl:ENSP00000392258.2|ensembl:ENSP00000419260.1|panther:PTHR10048(orthology-group)"	refseq:NP_395372.1|refseq:YP_093913.1|refseq:NP_857671.1|refseq:WP_002211799.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:by9ZmIbjn8roJ0j7/BbCwBMvCDg9606	rogid:EQfeZsF+Ifz/4ATGhKSB5pDt9HU632	intact-crc:0566A25940378FEF|rigid:/l36XFFgYuNVhtnUKIQPK8vuLHw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKJ1	uniprotkb:A0A2U2GWQ4	intact:EBI-965833|uniprotkb:Q8NHI1|ensembl:ENSP00000198536.2	intact:EBI-2845580|uniprotkb:Q74SR7|uniprotkb:Q0WDH9|uniprotkb:Q7CJQ8|uniprotkb:A0A380PMW3|uniprotkb:A0A384L966	psi-mi:pilra_human(display_long)|uniprotkb:PILRA(gene name)|psi-mi:PILRA(display_short)|uniprotkb:Inhibitory receptor PILR-alpha(gene name synonym)|uniprotkb:Cell surface receptor FDF03(gene name synonym)	psi-mi:a0a2u2gwq4_yerpe(display_long)|uniprotkb:mclA(gene name)|psi-mi:mclA(display_short)|uniprotkb:Regulator of SigE(gene name synonym)|uniprotkb:Sigma-E anti-sigma factor RseA(gene name synonym)|uniprotkb:Sigma-E factor negative regulatory protein(gene name synonym)|uniprotkb:rseA(gene name synonym)|uniprotkb:YPO2712(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861298|imex:IM-13779-6618	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_038467.2|refseq:NP_840056.1|refseq:NP_840057.1|ensembl:ENSG00000085514.16(gene)|ensembl:ENST00000198536.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR051694|rcsb pdb:3WUZ|rcsb pdb:3WV0|rcsb pdb:4NFB|rcsb pdb:5XO2|rcsb pdb:5XOF|reactome:R-HSA-198933|panther:PTHR15549(orthology-group)"	"interpro:IPR026279|interpro:IPR005573(Anti sigma-E protein RseA, C-terminal)|interpro:IPR005572(Anti sigma-E protein RseA, N-terminal)|go:""GO:0005886""(plasma membrane)|go:""GO:0016989""(sigma factor antagonist activity)|refseq:WP_002209673.1|interpro:IPR036147|refseq:YP_002347659.1|interpro:IPR052383"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QWSaRQHGXRXAOOMvijnTQztvSpY9606	rogid:LwZJGFoSTyhBT8PD/0j5gaZwEWc632	intact-crc:BA284B08C52B2E53|rigid:j4d5wokCUNcUkY5kyHwWHel3Y7A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA84	uniprotkb:Q13492	intact:EBI-2842602|uniprotkb:Q0WA86	intact:EBI-2803688|uniprotkb:Q86XZ9|uniprotkb:O60700|uniprotkb:Q6GMQ6|uniprotkb:B4DTM3|uniprotkb:E9PN05|uniprotkb:F8VPG7|uniprotkb:Q4LE54|ensembl:ENSP00000377015.3|intact:EBI-28967113	psi-mi:capp_yerpe(display_long)|uniprotkb:ppc(gene name)|psi-mi:ppc(display_short)|uniprotkb:YPO3929(locus name)|uniprotkb:y0308(locus name)|uniprotkb:YP_3121(locus name)	psi-mi:pical_human(display_long)|uniprotkb:CALM(gene name synonym)|uniprotkb:Clathrin assembly lymphoid myeloid leukemia protein(gene name synonym)|uniprotkb:PICALM(gene name)|psi-mi:PICALM(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861312|imex:IM-13779-6619	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033129|interpro:IPR021135|interpro:IPR018129|interpro:IPR022805|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006107""(oxaloacetate metabolic process)|go:""GO:0008964""(phosphoenolpyruvate carboxylase activity)|go:""GO:0015977""(carbon fixation)|refseq:WP_002209491.1|refseq:YP_002348802.1|panther:PTHR30523(orthology-group)"	"ensembl:ENSG00000073921.18(gene)|ensembl:ENST00000393346.8(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0005545""(1-phosphatidylinositol binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006897""(endocytosis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007409""(axonogenesis)|go:""GO:0007611""(learning or memory)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0009986""(cell surface)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016185""(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:""GO:0016188""(synaptic vesicle maturation)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030132""(clathrin coat of coated pit)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030276""(clathrin binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031623""(receptor internalization)|go:""GO:0031982""(vesicle)|go:""GO:0032050""(clathrin heavy chain binding)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0048156""(tau protein binding)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070381""(endosome to plasma membrane transport vesicle)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097418""(neurofibrillary tangle)|go:""GO:0097494""(regulation of vesicle size)|go:""GO:0097753""(membrane bending)|go:""GO:0098894""(extrinsic component of presynaptic endocytic zone membrane)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902991""(regulation of amyloid precursor protein catabolic process)|go:""GO:1902993""(positive regulation of amyloid precursor protein catabolic process)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:2000009""(negative regulation of protein localization to cell surface)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR045192|mint:Q13492|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9696264|refseq:NP_001008660.1|refseq:NP_001193875.1|refseq:NP_001193876.1|refseq:NP_009097.2|refseq:XP_005274388.1|efo:""Orphanet:99861""|panther:PTHR22951(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aPbGF+uF/gTYbtmc4Mkr1Ys0jNc632	rogid:UIZhYyYqmBCyN4xwPCl9PeCdK8Q9606	intact-crc:E2835D2110701630|rigid:s5VHxYpjIKFADSX4KD+J3eRGJV4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Burke et al. (2011)	mint:MINT-8173295|pubmed:21569203|imex:IM-16719|mint:fj-11-0115.r2	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8665283|mint:MINT-8173300|imex:IM-16719-1	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-8173302(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-8173303(identity)"	-	-	comment:mint	comment:mint|figure legend:f5b f6b f7a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.0x10^-6(molar)	2011/04/26	2025/03/25	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:A6FE0BF8312E6537|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:163-480(MINT-8173318)|mutation decreasing interaction:278-278(MINT-8173341)|mutation decreasing interaction:276-276(MINT-8173337)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Burke et al. (2011)	mint:MINT-8173295|pubmed:21569203|imex:IM-16719|mint:fj-11-0115.r2	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8665306|mint:MINT-8173347|imex:IM-16719-2	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-8173350(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-8173352(identity)"	-	-	comment:mint	figure legend:f7b|comment:mint|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:22.7x10^-6(molar)	2011/04/26	2025/03/25	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:000BA494FB1AB3CA|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	-	binding-associated region:309-480(MINT-8173357)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P02751	uniprotkb:Q53682	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-8398005|intact:MINT-7991086	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q53682_staau(display_long)|uniprotkb:GQX37_12780(orf name)|uniprotkb:SAMEA2078260_01108(orf name)|uniprotkb:NCTC13131_00002(orf name)|uniprotkb:fnbB(gene name)|psi-mi:fnbB(display_short)|uniprotkb:SAMEA2080344_00622(orf name)|uniprotkb:SAMEA2081063_00958(orf name)|uniprotkb:SAMEA70146418_00235(orf name)|uniprotkb:ACR74_11475(orf name)|uniprotkb:LB359_00215(orf name)|uniprotkb:SAMEA1029536_02750(orf name)|uniprotkb:SAMEA2078588_01190(orf name)|uniprotkb:SAMEA4008575_00785(orf name)|uniprotkb:ERS1058648_02239(orf name)	"psi-mi:""MI:0049""(filter binding)"	Burke et al. (2011)	mint:MINT-8173295|pubmed:21569203|imex:IM-16719|mint:fj-11-0115.r2	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8665330|mint:MINT-8173367|imex:IM-16719-3	intact-miscore:0.74	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)|mint:MINT-8173369(identity)"	"go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|interpro:IPR004237(Fibronectin binding repeat)|interpro:IPR011266(Fibrogen-binding, domain 2)|interpro:IPR011252(Fibrogen-binding, domain 1)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_000841422.1|interpro:IPR041171|interpro:IPR019931|mint:MINT-8173370(identity)"	-	-	comment:mint	comment:domino|comment:mint|figure legend:f8b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/04/26	2025/03/25	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:bfAMauHulbhUf2/F8M7vRYHFsPw1280	intact-crc:597D87EE585C242C|rigid:qkm6GXU5Oa9JuvYZq21kf8fyiiE	false	binding-associated region:1-273(MINT-8173373)	binding-associated region:163-480(MINT-8173380)	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:O60664	uniprotkb:A0A6L8PRN6	intact:EBI-725795|uniprotkb:Q53G77|uniprotkb:Q9BS03|uniprotkb:Q9UBD7|uniprotkb:Q9UP92|uniprotkb:A8K4Y9|uniprotkb:K7EQF4|intact:EBI-11103673|ensembl:ENSP00000221957.3	intact:EBI-2809795|uniprotkb:Q6KT17|uniprotkb:E9QTD7|uniprotkb:Q81QV1	psi-mi:plin3_human(display_long)|uniprotkb:Cargo selection protein TIP47(gene name synonym)|uniprotkb:47 kDa mannose 6-phosphate receptor-binding protein(gene name synonym)|uniprotkb:Placental protein 17(gene name synonym)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short)|uniprotkb:TIP47(gene name synonym)|uniprotkb:M6PRBP1(gene name synonym)|uniprotkb:Mannose-6-phosphate receptor-binding protein 1(gene name synonym)	psi-mi:a0a6l8prn6_bacan(display_long)|uniprotkb:GBAA_2314(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809792|imex:IM-13779-1397	author score:13|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001157666.1|refseq:NP_001157661.1|refseq:NP_005808.3|ensembl:ENSG00000105355.9(gene)|ensembl:ENST00000221957.9(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0010008""(endosome membrane)|go:""GO:0010890""(positive regulation of triglyceride storage)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019915""(lipid storage)|go:""GO:0030133""(transport vesicle)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0045296""(cadherin binding)|go:""GO:1905691""(lipid droplet disassembly)|interpro:IPR004279(Perilipin)|mint:O60664|reactome:R-HSA-163560|reactome:R-HSA-6811440|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9706019|panther:PTHR14024(orthology-group)"	interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR024696|refseq:WP_000249923.1|interpro:IPR051768|interpro:IPR036689	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:U+skqZ/oQtQscaEvfdh+AVnCCKA9606	rogid:F/oxRKTzWTtfjzkNdzflVMqhX0s1392	intact-crc:99F41302043C457D|rigid:/tfIAmcSEERKlhOiBedk8umEIPI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HKS1	uniprotkb:P13693	intact:EBI-2809755|uniprotkb:Q6HZ94|uniprotkb:Q6KT88|uniprotkb:E9R2X7|uniprotkb:E9R2X8|uniprotkb:A0A2P0HDM1|uniprotkb:Q81R24	intact:EBI-1783169|uniprotkb:Q6YLS2|uniprotkb:Q7Z4J4|uniprotkb:Q96EE2|uniprotkb:Q9UC70|intact:EBI-1058458|uniprotkb:B2R7E5|intact:EBI-5772926|uniprotkb:Q8TBK7|ensembl:ENSP00000431872.2	psi-mi:a0a6l7hks1_bacan(display_long)|uniprotkb:GBAA_2235(locus name)	psi-mi:tctp_human(display_long)|uniprotkb:TPT1(gene name)|psi-mi:TPT1(display_short)|uniprotkb:p23(gene name synonym)|uniprotkb:Histamine-releasing factor(gene name synonym)|uniprotkb:Fortilin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809760|imex:IM-13779-1394	author score:13|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR021860|interpro:IPR050491|refseq:WP_000034308.1	"refseq:NP_003286.1|refseq:NP_001273202.1|ensembl:ENSG00000133112.17(gene)|ensembl:ENST00000530705.6(transcript)|go:""GO:0000922""(spindle pole)|go:""GO:0003723""(RNA binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005771""(multivesicular body)|go:""GO:0005829""(cytosol)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0009615""(response to virus)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|interpro:IPR018103|interpro:IPR018105|interpro:IPR034737|mint:P13693|rcsb pdb:1YZ1|rcsb pdb:2HR9|rcsb pdb:3EBM|rcsb pdb:4Z9V|rcsb pdb:5O9L|rcsb pdb:5O9M|rcsb pdb:6IZB|rcsb pdb:6IZE|dip:DIP-40097N|panther:PTHR11991(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:s3ufynX4Z88i1hsIcrId1NlDw0o1392	rogid:1RijAyNqyKFL9LvKa9wbYtC4fRo9606	intact-crc:B09F43301D27F355|rigid:55Qtd4M0OsSgCZ3iPf9yLt5aUpc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AGK5	uniprotkb:Q86VP1	intact:EBI-2809816|uniprotkb:Q6KVT3|uniprotkb:Q6I1Z4|uniprotkb:E9QTJ8|uniprotkb:E9QTJ9|uniprotkb:Q81TR0|uniprotkb:A0A0F7RFQ0	intact:EBI-529518|uniprotkb:O60398|uniprotkb:O95770|uniprotkb:Q13311|uniprotkb:Q9BQG5|uniprotkb:Q9UI88|uniprotkb:B4DKU7|uniprotkb:E7ENV2|uniprotkb:A4D196|ensembl:ENSP00000379612.2	psi-mi:a0a6h3agk5_bacan(display_long)|uniprotkb:pepF1(gene name)|psi-mi:pepF1(display_short)|uniprotkb:GBAA_1206(locus name)	psi-mi:taxb1_human(display_long)|uniprotkb:TRAF6-binding protein(gene name synonym)|uniprotkb:TAX1BP1(gene name)|psi-mi:TAX1BP1(display_short)|uniprotkb:T6BP(gene name synonym)|uniprotkb:PRO0105(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809822|imex:IM-13779-1400	author score:12|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|interpro:IPR004438(Peptidase M3B, oligoendopeptidase F)|interpro:IPR013647(Peptidase M3B, oligopeptidase F, N-terminal)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006508""(proteolysis)|go:""GO:0006518""(peptide metabolic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000003398.1|interpro:IPR042088|interpro:IPR045090"	"refseq:NP_001073333.1|refseq:NP_001193830.1|refseq:NP_001193831.1|refseq:NP_006015.4|ensembl:ENSG00000106052.14(gene)|ensembl:ENST00000396319.7(transcript)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0005739""(mitochondrion)|go:""GO:0005776""(autophagosome)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0006915""(apoptotic process)|go:""GO:0019900""(kinase binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0034144""(negative regulation of toll-like receptor 4 signaling pathway)|go:""GO:0039532""(negative regulation of cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905161""(protein localization to phagocytic vesicle)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|interpro:IPR051002|mint:Q86VP1|rcsb pdb:2M7Q|rcsb pdb:4BMJ|rcsb pdb:4NLH|rcsb pdb:4Z4K|rcsb pdb:4Z4M|rcsb pdb:5AAS|rcsb pdb:5YT6|rcsb pdb:5Z7G|rcsb pdb:8W6A|rcsb pdb:8W6B|reactome:R-HSA-5357905|reactome:R-HSA-936440|dip:DIP-33010N|panther:PTHR31915(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gbqWViaR6w//z94aLZ1HFT5BjWE1392	rogid:OJfD9nSzpjJ3bMbHugSDVJ9fj/E9606	intact-crc:96938FEC8FA09433|rigid:iRyceYob48EBr4jS8D8+UyZQ9ZM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PRN6	uniprotkb:O15126	intact:EBI-2809795|uniprotkb:Q6KT17|uniprotkb:E9QTD7|uniprotkb:Q81QV1	intact:EBI-954338|uniprotkb:O43587|uniprotkb:Q96BX1|uniprotkb:Q96QK5|uniprotkb:Q6FG23|ensembl:ENSP00000481022.1	psi-mi:a0a6l8prn6_bacan(display_long)|uniprotkb:GBAA_2314(locus name)	psi-mi:scam1_human(display_long)|uniprotkb:SCAMP1(gene name)|psi-mi:SCAMP1(display_short)|uniprotkb:SCAMP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809829|imex:IM-13779-1399	author score:12|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR024696|refseq:WP_000249923.1|interpro:IPR051768|interpro:IPR036689	"refseq:NP_004857.4|refseq:NP_001277158.1|ensembl:ENSG00000085365.18(gene)|ensembl:ENST00000621999.5(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0055038""(recycling endosome membrane)|interpro:IPR007273(SCAMP)|mint:O15126|reactome:R-HSA-6798695|panther:PTHR10687(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:F/oxRKTzWTtfjzkNdzflVMqhX0s1392	rogid:Utuf4fnpMHS2yG4zfccdB2enfxI9606	intact-crc:325DF69C9D1DBE41|rigid:gVdTxDrEgg9+SbzgCcC596iQ+M0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:Q81LD0	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2809803|uniprotkb:Q6KM26|uniprotkb:Q6HST3	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:gsa2_bacan(display_long)|uniprotkb:hemL2(gene name)|psi-mi:hemL2(display_short)|uniprotkb:Glutamate-1-semialdehyde aminotransferase 2(gene name synonym)|uniprotkb:BA_4693(locus name)|uniprotkb:GBAA_4693(locus name)|uniprotkb:BAS4358(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809809|imex:IM-13779-1398	author score:13|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR004639(Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|rcsb pdb:3K28|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0042286""(glutamate-1-semialdehyde 2,1-aminomutase activity)|refseq:WP_001224513.1|refseq:NP_846906.1|refseq:YP_030605.1|interpro:IPR049704"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:GnZPBZpKvZpcwazgpwseq6iVQbg1392	intact-crc:C0B087ED46217974|rigid:8B9tp31KUKfY9enceVJ4cMpvIDE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2B3Y6C6	uniprotkb:P19838	intact:EBI-2809836|uniprotkb:A0A1V4BKN1|uniprotkb:Q6HS64|uniprotkb:Q6KLG4|uniprotkb:E9R1Z0|uniprotkb:E9R1Z1|uniprotkb:Q81KQ8	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a2b3y6c6_bacan(display_long)|uniprotkb:GBAA_4932(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809841|imex:IM-13779-1403	author score:12|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009293(Protein of unknown function DUF948, bacterial)|go:""GO:0016020""(membrane)|refseq:WP_001197726.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:bq85IyqkiV02z9B9bgDu4A+z+cU1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:DA7390E59185466F|rigid:atE1jdsbNWYaqAt+EJEBA45rSPw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q02447	uniprotkb:A0A6L8P6L1	intact:EBI-348158|intact:EBI-28978002|uniprotkb:A0AVL9|uniprotkb:Q69B26|uniprotkb:Q69B27|uniprotkb:Q8TD56|uniprotkb:Q8WWU4|uniprotkb:Q9BQR1|uniprotkb:B4E2B7|ensembl:ENSP00000310301.6	intact:EBI-2809878|uniprotkb:Q6I3Z2|uniprotkb:Q6KXQ4|uniprotkb:E9R1Y7|uniprotkb:E9R1Y8|uniprotkb:Q81Z52|uniprotkb:A0A0F7RMG3	psi-mi:sp3_human(display_long)|uniprotkb:SPR-2(gene name synonym)|uniprotkb:SP3(gene name)|psi-mi:SP3(display_short)	psi-mi:a0a6l8p6l1_bacan(display_long)|uniprotkb:GBAA_0421(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809875|imex:IM-13779-1402	author score:11|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001017371.3|refseq:NP_001166183.1|refseq:NP_003102.1|ensembl:ENSG00000172845.18(gene)|ensembl:ENST00000310015.12(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001503""(ossification)|go:""GO:0001779""(natural killer cell differentiation)|go:""GO:0001829""(trophectodermal cell differentiation)|go:""GO:0001889""(liver development)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0002318""(myeloid progenitor cell differentiation)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016605""(PML body)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030219""(megakaryocyte differentiation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030851""(granulocyte differentiation)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0043353""(enucleate erythrocyte differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048596""(embryonic camera-type eye morphogenesis)|go:""GO:0048706""(embryonic skeletal system development)|go:""GO:0060136""(embryonic process involved in female pregnancy)|go:""GO:0060216""(definitive hemopoiesis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q02447|reactome:R-HSA-3232118|panther:PTHR23235(orthology-group)"	"interpro:IPR007197(Radical SAM)|interpro:IPR014866(YfkB-like domain)|interpro:IPR013785(Aldolase-type TIM barrel)|go:""GO:0003824""(catalytic activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR031004|refseq:WP_000156003.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VXqjICYbtoDWPEw2j4UCNGo7MvU9606	rogid:BSJ0SMeZprDBEfO9AnyN2+GNdiI1392	intact-crc:9F455A0CFB05FFC5|rigid:+ansSEFLCuqonjt5kyMWUtWXfPE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14964	uniprotkb:A0A6L7H1C2	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201.4|ensembl:ENSP00000504106.1	intact:EBI-2809848|uniprotkb:Q6KMV0|uniprotkb:Q6HTL0|uniprotkb:E9QWV5|uniprotkb:E9QWV6|uniprotkb:A0A2P0HIT1|uniprotkb:Q81M57	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:a0a6l7h1c2_bacan(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:GBAA_4397(locus name)|uniprotkb:Recombination protein N(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809854|imex:IM-13779-1401	author score:12|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004703.1|ensembl:ENSG00000185359.14(gene)|ensembl:ENST00000329138.9(transcript)|ensembl:ENST00000676546.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010324""(membrane invagination)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010642""(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:""GO:0016197""(endosomal transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033565""(ESCRT-0 complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0042176""(regulation of protein catabolic process)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043405""(regulation of MAP kinase activity)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0090148""(membrane fission)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:1903543""(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|dip:DIP-29050N|panther:PTHR46275(orthology-group)"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|refseq:WP_000947756.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:aXVFQ2/u7+QhLnMBoqc0Kc6RtX01392	intact-crc:BB19A8A354EE73DE|rigid:nDesJH6B0It+hbKs//F8/0d4224	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HJT4	uniprotkb:Q96AE4	intact:EBI-2809861|uniprotkb:Q6KQT1|uniprotkb:Q6HWN8|uniprotkb:E9R665|uniprotkb:E9R666|uniprotkb:A0A2P0HGD7|uniprotkb:Q81NH4	intact:EBI-711404|ensembl:ENSP00000359804.2|uniprotkb:Q12828	psi-mi:a0a6l7hjt4_bacan(display_long)|uniprotkb:cypD(gene name)|psi-mi:cypD(display_short)|uniprotkb:GBAA_3221(locus name)	psi-mi:fubp1_human(display_long)|uniprotkb:FUBP1(gene name)|psi-mi:FUBP1(display_short)|uniprotkb:DNA helicase V(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809868|imex:IM-13779-1404	author score:12|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023206|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR017927|interpro:IPR001094(Flavodoxin-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR017938|interpro:IPR029039|go:""GO:0003958""(NADPH-hemoprotein reductase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0010181""(FMN binding)|go:""GO:0020037""(heme binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070330""(aromatase activity)|refseq:WP_000359079.1|interpro:IPR023173|interpro:IPR036396|interpro:IPR039261"	"ensembl:ENSG00000162613.18(gene)|ensembl:ENST00000370768.7(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010628""(positive regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|interpro:IPR048249|interpro:IPR048250|interpro:IPR048251|interpro:IPR048252|mint:Q96AE4|rcsb pdb:1J4W|rcsb pdb:2KXH|rcsb pdb:4LIJ|rcsb pdb:6Y24|rcsb pdb:6Y2C|rcsb pdb:6Y2D|rcsb pdb:8P25|refseq:NP_003893.2|refseq:NP_001290362.1|refseq:XP_016858232.1|dip:DIP-47273N|panther:PTHR10288(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zhoaOvUxUjv19qj1am2VKlovHG81392	rogid:38IaQgYv8qLMAryXO0lbfzgjjsM9606	intact-crc:A731DFD4FE98B3E0|rigid:0wtIWUwMZZftUjiIc2yL88EyuWo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:Q7Z3K3	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809938|imex:IM-13779-1409	author score:10|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	intact-crc:C4C709299CB5B53F|rigid:dKTu4LeQwSRwnVR8CZdeHJpKkcQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:P46379	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809917|imex:IM-13779-1408	author score:11|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:0338221445914AEB|rigid:14VGjJqH7soIj5mlc3i+n6jiLWg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:Q96T58	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-765739|uniprotkb:Q9UQ01|uniprotkb:Q9Y556|uniprotkb:Q9H9A8|uniprotkb:Q9NWH5|ensembl:ENSP00000364912.3|intact:EBI-28975565	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:mint_human(display_long)|uniprotkb:SPEN homolog(gene name synonym)|uniprotkb:SMART/HDAC1-associated repressor protein(gene name synonym)|uniprotkb:KIAA0929(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:SHARP(gene name synonym)|uniprotkb:SPEN(gene name)|psi-mi:SPEN(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809897|imex:IM-13779-1407	author score:11|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"efo:""Orphanet:1606""|ensembl:ENSG00000065526.13(gene)|ensembl:ENST00000375759.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034172|interpro:IPR034173|interpro:IPR034174|interpro:IPR034175|interpro:IPR035979|interpro:IPR049093|interpro:IPR049094|interpro:IPR049095|mint:Q96T58|rcsb pdb:1OW1|rcsb pdb:2RT5|rcsb pdb:4P6Q|rcsb pdb:7Z1K|reactome:R-HSA-9013422|refseq:NP_055816.2|dip:DIP-34569N|efo:""Orphanet:662234""|panther:PTHR23189(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:m7bdkKVATaG4dkFG/BYXRn4jOIk9606	intact-crc:D5F371BFF8EB9249|rigid:o+osRDfv7FaH62IHqRnoqcifw6U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VV7	uniprotkb:O14964	intact:EBI-2809904|uniprotkb:Q6I4W1|uniprotkb:Q6KYK5	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201.4|ensembl:ENSP00000504106.1	psi-mi:disa_bacan(display_long)|uniprotkb:disA(gene name)|psi-mi:disA(display_short)|uniprotkb:Cyclic di-AMP synthase(gene name synonym)|uniprotkb:Diadenylate cyclase(gene name synonym)|uniprotkb:BAS0083(locus name)|uniprotkb:BA_0082(locus name)|uniprotkb:GBAA_0082(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809910|imex:IM-13779-1405	author score:11|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018906|interpro:IPR003390(Protein of unknown function DUF147)|interpro:IPR023763|interpro:IPR010994(RuvA domain 2-like)|refseq:WP_000392168.1|interpro:IPR050338|go:""GO:0003677""(DNA binding)|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0106408""(diadenylate cyclase activity)|interpro:IPR038331|interpro:IPR036888|refseq:NP_842651.1|refseq:YP_026369.1"	"refseq:NP_004703.1|ensembl:ENSG00000185359.14(gene)|ensembl:ENST00000329138.9(transcript)|ensembl:ENST00000676546.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010324""(membrane invagination)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010642""(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:""GO:0016197""(endosomal transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033565""(ESCRT-0 complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0042176""(regulation of protein catabolic process)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043405""(regulation of MAP kinase activity)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0090148""(membrane fission)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:1903543""(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|dip:DIP-29050N|panther:PTHR46275(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:w05jKsotbORB695Nm44K6s+jHHk1392	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:EBF97FF06192E518|rigid:yujelfHQT4gQRInt5dR/JIdcE+k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H1G2	uniprotkb:Q9H4A3	intact:EBI-2809927	intact:EBI-457907|uniprotkb:O15052|uniprotkb:P54963|uniprotkb:Q86WL5|uniprotkb:Q8N673|uniprotkb:Q9P1S9|uniprotkb:Q4VBX9|intact:EBI-948424|uniprotkb:A1L4B0|uniprotkb:Q6IFS5|uniprotkb:C5HTZ5|uniprotkb:C5HTZ6|uniprotkb:C5HTZ7|uniprotkb:H6WZW3|uniprotkb:Q96CZ6|ensembl:ENSP00000313059.6	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	psi-mi:wnk1_human(display_long)|uniprotkb:WNK1(gene name)|psi-mi:WNK1(display_short)|uniprotkb:KDP(gene name synonym)|uniprotkb:KIAA0344(gene name synonym)|uniprotkb:PRKWNK1(gene name synonym)|uniprotkb:Protein kinase with no lysine 1(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 1(gene name synonym)|uniprotkb:Erythrocyte 65 kDa protein(gene name synonym)|uniprotkb:Kinase deficient protein(gene name synonym)|uniprotkb:HSN2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809924|imex:IM-13779-1406	author score:10|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"efo:""Orphanet:88940""|efo:""Orphanet:970""|ensembl:ENSG00000060237.19(gene)|ensembl:ENST00000315939.11(transcript)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0007165""(signal transduction)|go:""GO:0007507""(heart development)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010766""(negative regulation of sodium ion transport)|go:""GO:0010793""(regulation of mRNA export from nucleus)|go:""GO:0010820""(positive regulation of T cell chemotaxis)|go:""GO:0016020""(membrane)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0030644""(intracellular chloride ion homeostasis)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033633""(negative regulation of cell-cell adhesion mediated by integrin)|go:""GO:0034115""(negative regulation of heterotypic cell-cell adhesion)|go:""GO:0034260""(negative regulation of GTPase activity)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038116""(""chemokine (C-C motif) ligand 21 signaling pathway"")|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048666""(neuron development)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0055075""(potassium ion homeostasis)|go:""GO:0055080""(monoatomic cation homeostasis)|go:""GO:0071474""(cellular hyperosmotic response)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090188""(negative regulation of pancreatic juice secretion)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097022""(lymphocyte migration into lymph node)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1902305""(regulation of sodium ion transmembrane transport)|go:""GO:1903038""(negative regulation of leukocyte cell-cell adhesion)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:1903490""(positive regulation of mitotic cytokinesis)|go:""GO:1904062""(regulation of monoatomic cation transmembrane transport)|go:""GO:1904595""(positive regulation of termination of RNA polymerase II transcription)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990869""(cellular response to chemokine)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|interpro:IPR050588|mint:Q9H4A3|rcsb pdb:4PWN|rcsb pdb:5TF9|rcsb pdb:5WDY|rcsb pdb:5WE8|rcsb pdb:6FBK|reactome:R-HSA-2672351|refseq:NP_001171914.1|refseq:NP_055638.2|refseq:NP_061852.3|refseq:NP_998820.3|refseq:XP_016875326.1|refseq:XP_016875327.1|dip:DIP-32648N|panther:PTHR24361(orthology-group)|ensembl:ENSP00000313059.6|ensembl:ENST00000340908.9|ensembl:ENSP00000341292.5|ensembl:ENST00000530271.6|ensembl:ENSP00000433548.3|ensembl:ENST00000537687.5|ensembl:ENSP00000444465.1|ensembl:ENST00000675631.1|ensembl:ENSP00000502415.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/06	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	rogid:Jt4cvhSumyRRIZDmWgj4GsG7wjQ9606	intact-crc:24840DDE5E447BE1|rigid:SpQdOZPYclVetGhBBNc78Za8e48	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UL45	uniprotkb:Q81VV7	intact:EBI-465781|ensembl:ENSP00000220531.4	intact:EBI-2809904|uniprotkb:Q6I4W1|uniprotkb:Q6KYK5	psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym)	psi-mi:disa_bacan(display_long)|uniprotkb:disA(gene name)|psi-mi:disA(display_short)|uniprotkb:Cyclic di-AMP synthase(gene name synonym)|uniprotkb:Diadenylate cyclase(gene name synonym)|uniprotkb:BAS0083(locus name)|uniprotkb:BA_0082(locus name)|uniprotkb:GBAA_0082(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809945|imex:IM-13779-1410	author score:10|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:231531""|panther:PTHR31328(orthology-group)|ensembl:ENSG00000104164.12(gene)|ensembl:ENST00000220531.9(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0001822""(kidney development)|go:""GO:0002936""(bradykinin biosynthetic process)|go:""GO:0003016""(respiratory system process)|go:""GO:0003158""(endothelium development)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006536""(glutamate metabolic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0006605""(protein targeting)|go:""GO:0006644""(phospholipid metabolic process)|go:""GO:0007596""(blood coagulation)|go:""GO:0007613""(memory)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010467""(gene expression)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016081""(synaptic vesicle docking)|go:""GO:0019905""(syntaxin binding)|go:""GO:0021542""(dentate gyrus development)|go:""GO:0021854""(hypothalamus development)|go:""GO:0030133""(transport vesicle)|go:""GO:0030318""(melanocyte differentiation)|go:""GO:0031083""(BLOC-1 complex)|go:""GO:0031175""(neuron projection development)|go:""GO:0031941""(filamentous actin)|go:""GO:0032402""(melanosome transport)|go:""GO:0032438""(melanosome organization)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0033299""(secretion of lysosomal enzymes)|go:""GO:0033484""(intracellular nitric oxide homeostasis)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0042311""(vasodilation)|go:""GO:0042745""(circadian sleep/wake cycle)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043227""(membrane-bounded organelle)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0046085""(adenosine metabolic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0048286""(lung alveolus development)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050942""(positive regulation of pigment cell differentiation)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060271""(cilium assembly)|go:""GO:0061025""(membrane fusion)|go:""GO:0070938""(contractile ring)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0098793""(presynapse)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1905144""(response to acetylcholine)|go:""GO:1990742""(microvesicle)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1"	"interpro:IPR018906|interpro:IPR003390(Protein of unknown function DUF147)|interpro:IPR023763|interpro:IPR010994(RuvA domain 2-like)|refseq:WP_000392168.1|interpro:IPR050338|go:""GO:0003677""(DNA binding)|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0106408""(diadenylate cyclase activity)|interpro:IPR038331|interpro:IPR036888|refseq:NP_842651.1|refseq:YP_026369.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606	rogid:w05jKsotbORB695Nm44K6s+jHHk1392	intact-crc:828D9C0E2AC5A771|rigid:DNYhQ5wmHeWtJo5Y+0UcBg73OXE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96BD5	uniprotkb:Q81KT8	intact:EBI-745085|uniprotkb:Q6AWA2|uniprotkb:Q9C0G7|uniprotkb:Q9H8V9|uniprotkb:Q9HAK6|uniprotkb:Q9NZE9|uniprotkb:D3DQP5|ensembl:ENSP00000398824.2	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	psi-mi:pf21a_human(display_long)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name)	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809952|imex:IM-13779-1412	author score:9|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:52022""|dip:DIP-60252N|ensembl:ENSG00000135365.17(gene)|ensembl:ENST00000418153.6(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0046872""(metal ion binding)|go:""GO:1990391""(DNA repair complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q96BD5|rcsb pdb:2PUY|rcsb pdb:2YQL|reactome:R-HSA-3214815|reactome:R-HSA-9679191|reactome:R-HSA-983231|refseq:NP_001095272.1|refseq:NP_057705.3|refseq:XP_005253022.1|refseq:XP_011518475.1|refseq:XP_011518476.1|refseq:XP_011518481.1|refseq:XP_016873380.1|panther:PTHR24102(orthology-group)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/12	rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	intact-crc:D220A0CB71556C16|rigid:CHxpULQENM+ePqOeYrfICMOBw64	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q00987	uniprotkb:A0A6L7H4A4	intact:EBI-389668|intact:EBI-28980679|uniprotkb:A6NL51|uniprotkb:Q13226|uniprotkb:Q13297|uniprotkb:Q13298|uniprotkb:Q13299|uniprotkb:Q13300|uniprotkb:Q13301|uniprotkb:Q53XW0|uniprotkb:Q71TW9|uniprotkb:Q8WYJ1|uniprotkb:Q8WYJ2|uniprotkb:Q9UGI3|uniprotkb:Q9UMT8|uniprotkb:A8K2S6|ensembl:ENSP00000444430.2	intact:EBI-2809965|uniprotkb:Q6KS98|uniprotkb:E9QYD6|uniprotkb:A0A2P0HEH6|uniprotkb:Q81Q14	psi-mi:mdm2_human(display_long)|uniprotkb:MDM2(gene name)|psi-mi:MDM2(display_short)|uniprotkb:p53-binding protein Mdm2(gene name synonym)|uniprotkb:Oncoprotein Mdm2(gene name synonym)|uniprotkb:Double minute 2 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Mdm2(gene name synonym)	psi-mi:a0a6l7h4a4_bacan(display_long)|uniprotkb:GBAA_2625(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809969|imex:IM-13779-1411	author score:9|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR46858(orthology-group)|rcsb pdb:4JVE|rcsb pdb:4JVR|rcsb pdb:4JWR|rcsb pdb:4MDN|rcsb pdb:4MDQ|rcsb pdb:4OAS|rcsb pdb:4OBA|rcsb pdb:4OCC|rcsb pdb:4ODE|rcsb pdb:4ODF|rcsb pdb:4OGN|rcsb pdb:4OGT|rcsb pdb:4OGV|rcsb pdb:4OQ3|rcsb pdb:4QO4|rcsb pdb:4QOC|rcsb pdb:4UD7|rcsb pdb:4UE1|rcsb pdb:4UMN|rcsb pdb:4WT2|rcsb pdb:4XXB|rcsb pdb:4ZFI|rcsb pdb:4ZGK|rcsb pdb:4ZYC|rcsb pdb:4ZYF|rcsb pdb:4ZYI|rcsb pdb:5AFG|rcsb pdb:5C5A|rcsb pdb:5HMH|rcsb pdb:5HMI|rcsb pdb:5HMK|rcsb pdb:5J7F|rcsb pdb:5J7G|rcsb pdb:5LAV|rcsb pdb:5LAW|rcsb pdb:5LAY|rcsb pdb:5LAZ|rcsb pdb:5LN2|rcsb pdb:5MNJ|rcsb pdb:5OAI|rcsb pdb:5OC8|rcsb pdb:5SWK|rcsb pdb:5TRF|rcsb pdb:5UMM|rcsb pdb:5VK0|rcsb pdb:5WTS|rcsb pdb:5XXK|rcsb pdb:5Z02|rcsb pdb:5ZXF|rcsb pdb:6AAW|rcsb pdb:6GGN|rcsb pdb:6H22|rcsb pdb:6HFA|rcsb pdb:6I29|rcsb pdb:6I3S|rcsb pdb:6IM9|rcsb pdb:6KZU|rcsb pdb:6Q96|rcsb pdb:6Q9H|rcsb pdb:6Q9L|rcsb pdb:6Q9O|rcsb pdb:6SQO|rcsb pdb:6T2D|rcsb pdb:6T2E|rcsb pdb:6T2F|rcsb pdb:6Y4Q|rcsb pdb:6YR6|rcsb pdb:7AD0|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7AYE|rcsb pdb:7BIR|rcsb pdb:7BIT|rcsb pdb:7BIV|rcsb pdb:7BJ0|rcsb pdb:7BJ6|rcsb pdb:7BMG|rcsb pdb:7KJM|rcsb pdb:7NA1|rcsb pdb:7NA2|rcsb pdb:7NA3|rcsb pdb:7NA4|rcsb pdb:7NUS|rcsb pdb:7QDQ|rcsb pdb:8AEU|rcsb pdb:8BGU|rcsb pdb:8EI9|rcsb pdb:8EIA|rcsb pdb:8EIB|rcsb pdb:8EIC|rcsb pdb:8F0Z|rcsb pdb:8F10|ensembl:ENSG00000135679.27(gene)|ensembl:ENST00000539479.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001568""(blood vessel development)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0002039""(p53 binding)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003283""(atrial septum development)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0007089""(traversing start control point of mitotic cell cycle)|go:""GO:0008097""(5S rRNA binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010039""(response to iron ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010955""(negative regulation of protein processing)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016567""(protein ubiquitination)|rcsb pdb:8F12|rcsb pdb:8F13|rcsb pdb:8GCG|rcsb pdb:8J81|go:""GO:0016874""(ligase activity)|go:""GO:0016925""(protein sumoylation)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019789""(SUMO transferase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0032026""(response to magnesium ion)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042176""(regulation of protein catabolic process)|go:""GO:0042220""(response to cocaine)|go:""GO:0042802""(identical protein binding)|go:""GO:0042975""(peroxisome proliferator activated receptor binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045472""(response to ether)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061663""(NEDD8 ligase activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071301""(cellular response to vitamin B1)|go:""GO:0071312""(cellular response to alkaloid)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0071391""(cellular response to estrogen stimulus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071494""(cellular response to UV-C)|go:""GO:0072537""(fibroblast activation)|go:""GO:0072717""(cellular response to actinomycin D)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:0099576""(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:""GO:1901797""(negative regulation of signal transduction by p53 class mediator)|go:""GO:1902254""(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:1904404""(response to formaldehyde)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904754""(positive regulation of vascular associated smooth muscle cell migration)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990785""(response to water-immersion restraint stress)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016495(p53 negative regulator Mdm2/Mdm4)|interpro:IPR028340|interpro:IPR036443|interpro:IPR036885|interpro:IPR044080|mint:Q00987|rcsb pdb:1RV1|rcsb pdb:1T4E|rcsb pdb:1T4F|rcsb pdb:1YCR|rcsb pdb:1Z1M|rcsb pdb:2AXI|rcsb pdb:2C6A|rcsb pdb:2C6B|rcsb pdb:2F1Y|rcsb pdb:2FOP|rcsb pdb:2GV2|rcsb pdb:2HDP|rcsb pdb:2LZG|rcsb pdb:2M86|rcsb pdb:2MPS|rcsb pdb:2RUH|rcsb pdb:2VJE|rcsb pdb:2VJF|rcsb pdb:3EQS|rcsb pdb:3G03|rcsb pdb:3IUX|rcsb pdb:3IWY|rcsb pdb:3JZK|rcsb pdb:3JZR|rcsb pdb:3JZS|rcsb pdb:3LBK|rcsb pdb:3LBL|rcsb pdb:3LNJ|rcsb pdb:3LNZ|rcsb pdb:3MQS|rcsb pdb:3TJ2|rcsb pdb:3TPX|rcsb pdb:3TU1|rcsb pdb:3V3B|rcsb pdb:3VBG|rcsb pdb:3VZV|rcsb pdb:3W69|rcsb pdb:4DIJ|rcsb pdb:4ERE|rcsb pdb:4ERF|rcsb pdb:4HBM|rcsb pdb:4HFZ|rcsb pdb:4HG7|rcsb pdb:4JV7|rcsb pdb:4JV9|rcsb pdb:8P0D|rcsb pdb:8PWC|reactome:R-HSA-198323|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-399719|reactome:R-HSA-5674400|reactome:R-HSA-5689880|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69541|reactome:R-HSA-8941858|reactome:R-HSA-9725370|reactome:R-HSA-9768919|refseq:NP_001138811.1|refseq:NP_001265391.1|refseq:NP_002383.2|refseq:XP_005268929.1|refseq:XP_006719462.1|efo:""Orphanet:99970""|efo:""Orphanet:99971""|efo:""Orphanet:524""|dip:DIP-392N|ensembl:ENST00000258149.11|ensembl:ENSP00000258149.6|ensembl:ENST00000299252.8|ensembl:ENSP00000299252.4|ensembl:ENST00000360430.6|ensembl:ENSP00000353611.2|ensembl:ENST00000393413.7|ensembl:ENSP00000377065.3|ensembl:ENSP00000444430.2"	interpro:IPR014973(Protein of unknown function DUF1835)|interpro:IPR022123|refseq:WP_000565732.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:CFy2L9Et1jFtlApOFn2AKiGPWJ89606	rogid:OLXAdJsxl+6W4jWwUZ6ORz1SQzs1392	intact-crc:F87ED4FCF5B14012|rigid:IH//5GCbW3otXUz5b6KoGgvzOLc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:Q86T24	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-2515625|uniprotkb:Q7Z361|uniprotkb:Q8N3P0|uniprotkb:Q8IVP6|uniprotkb:O00319|uniprotkb:B2R5U6|ensembl:ENSP00000314153.2|ensembl:ENSP00000450969.1	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:kaiso_human(display_long)|uniprotkb:ZBTB33(gene name)|psi-mi:ZBTB33(display_short)|uniprotkb:KAISO(gene name synonym)|uniprotkb:ZNF348(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 33(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809988|imex:IM-13779-1413	author score:9|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"refseq:NP_001171671.1|refseq:NP_006768.1|ensembl:ENSG00000177485.7(gene)|ensembl:ENST00000326624.2(transcript)|ensembl:ENST00000557385.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008327""(methyl-CpG binding)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050457|mint:Q86T24|rcsb pdb:2LT7|rcsb pdb:3FKC|rcsb pdb:3M4T|rcsb pdb:3M8V|rcsb pdb:4F6M|rcsb pdb:4F6N|rcsb pdb:5VMU|rcsb pdb:5VMV|rcsb pdb:5VMW|rcsb pdb:5VMX|rcsb pdb:5VMY|rcsb pdb:5VMZ|rcsb pdb:6DF5|rcsb pdb:6DF8|rcsb pdb:6DF9|rcsb pdb:6DFA|rcsb pdb:6DFB|rcsb pdb:6DFC|rcsb pdb:6V8U|panther:PTHR24399(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:nD+3FCTCYxUrXZXpBW5Co1V0CHc9606	intact-crc:3EC3572BD30B3C7B|rigid:p3GATUUql6N1iKDyqrRB/zK35e4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7L513	uniprotkb:A0A6L7HB35	intact:EBI-2806840|uniprotkb:Q5VXA1|uniprotkb:Q5VXA3|uniprotkb:Q5VXA2|uniprotkb:Q9BR57|uniprotkb:Q96PJ2|uniprotkb:Q96PJ0|uniprotkb:Q5VXA4|uniprotkb:Q8NEW4|uniprotkb:Q96PJ1|uniprotkb:Q8WXH3|uniprotkb:Q96PC6|uniprotkb:A0N0M1|uniprotkb:Q5VXB0|uniprotkb:Q96PJ4|ensembl:ENSP00000236938.7|uniprotkb:A6NC03|uniprotkb:A6NL20|uniprotkb:F5H720|uniprotkb:F8W743|uniprotkb:G3V1J2|uniprotkb:Q5VXB1	intact:EBI-2810010|uniprotkb:Q6KX90|uniprotkb:Q6I3H7|uniprotkb:E9QTP4|uniprotkb:E9QTP5|uniprotkb:A0A2P0HA09|uniprotkb:Q81V90	psi-mi:fcrla_human(display_long)|uniprotkb:FCRL(gene name synonym)|uniprotkb:FCRL1(gene name synonym)|uniprotkb:FCRLM1(gene name synonym)|uniprotkb:FCRX(gene name synonym)|uniprotkb:FREB(gene name synonym)|uniprotkb:Fc receptor homolog expressed in B-cells(gene name synonym)|uniprotkb:Fc receptor-like and mucin-like protein 1(gene name synonym)|uniprotkb:Fc receptor-like protein(gene name synonym)|uniprotkb:Fc receptor-related protein X(gene name synonym)|uniprotkb:UNQ291/PRO329(orf name)|uniprotkb:FCRLA(gene name)|psi-mi:FCRLA(display_short)	psi-mi:a0a6l7hb35_bacan(display_long)|uniprotkb:aspA1(gene name)|psi-mi:aspA1(display_short)|uniprotkb:GBAA_0609(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810007|imex:IM-13779-1414	author score:9|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001171795.1|refseq:NP_001171796.1|refseq:NP_001171799.1|refseq:NP_001171800.1|refseq:NP_001171801.1|refseq:NP_001171802.1|refseq:NP_116127.3|ensembl:ENSG00000132185.18(gene)|ensembl:ENST00000236938.12(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030154""(cell differentiation)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050488|rcsb pdb:4HWN|panther:PTHR11481(orthology-group)"	"interpro:IPR004708(Aspartate ammonia-lyase)|interpro:IPR018951|interpro:IPR000362(Fumarate lyase)|interpro:IPR020557|interpro:IPR008948(L-Aspartase-like)|interpro:IPR024083|interpro:IPR022761|interpro:IPR051546|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006531""(aspartate metabolic process)|go:""GO:0008797""(aspartate ammonia-lyase activity)|refseq:WP_000562147.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8IN4JYjINzn29PadL0irqR3sSeE9606	rogid:nnzLQtRPCMiP6XJ4eU50JaPldIo1392	intact-crc:DF3AB1AAC5EA8DDF|rigid:nPizp6S8F9MXPvOvIPZfp9ooyh0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14232	uniprotkb:A0A6H3A7J7	intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|ensembl:ENSP00000416250.2|uniprotkb:B4DGX0	intact:EBI-2810023|uniprotkb:Q6KSW8|uniprotkb:Q6HYX2|uniprotkb:E9RE10|uniprotkb:E9RE11|uniprotkb:A0A2P0HE73|uniprotkb:Q81QQ0	psi-mi:ei2ba_human(display_long)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym)|uniprotkb:eIF2B GDP-GTP exchange factor subunit alpha(gene name synonym)	psi-mi:a0a6h3a7j7_bacan(display_long)|uniprotkb:Isochorismate mutase(gene name synonym)|uniprotkb:GBAA_2369(locus name)|uniprotkb:dhbC(gene name)|psi-mi:dhbC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810020|imex:IM-13779-1417	author score:9|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:157713""|efo:""Orphanet:157716""|efo:""Orphanet:157719""|efo:""Orphanet:99853""|efo:""Orphanet:99854""|ensembl:ENSG00000111361.13(gene)|ensembl:ENST00000424014.7(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005851""(eukaryotic translation initiation factor 2B complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0009408""(response to heat)|go:""GO:0009749""(response to glucose)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|interpro:IPR051501|mint:Q14232|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7F64|rcsb pdb:7F66|rcsb pdb:7F67|rcsb pdb:7KMA|rcsb pdb:7KMF|rcsb pdb:7L70|rcsb pdb:7L7G|rcsb pdb:7RLO|rcsb pdb:7TRJ|rcsb pdb:7VLK|rcsb pdb:8TQZ|reactome:R-HSA-72731|refseq:NP_001405.1|panther:PTHR45860(orthology-group)"	"interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR015890(Chorismate binding, C-terminal)|interpro:IPR004561(Isochorismate synthase)|rcsb pdb:3OS6|go:""GO:0008909""(isochorismate synthase activity)|go:""GO:0009697""(salicylic acid biosynthetic process)|refseq:WP_001001950.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606	rogid:DddlWEIOGPuLygNtt3eH2rRSQdQ1392	intact-crc:BB354DBD012C5586|rigid:o43cTL1tXmltHkwZjpxLRjvOseU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCC8	uniprotkb:A0A6L7H6I4	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	intact:EBI-2809998|uniprotkb:Q6KRP7|uniprotkb:Q6HXM1|uniprotkb:E9R229|uniprotkb:E9R230|uniprotkb:Q81PF8|uniprotkb:A0A0F7RD29	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	psi-mi:a0a6l7h6i4_bacan(display_long)|uniprotkb:GBAA_2849(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809995|imex:IM-13779-1416	author score:9|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"interpro:IPR000064(NLP/P60)|interpro:IPR051202|go:""GO:0008234""(cysteine-type peptidase activity)|refseq:WP_000755447.1|interpro:IPR038765|interpro:IPR041382"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	rogid:8a3L7UT/Zan1MKYf6EjLItnqBqY1392	intact-crc:69A51490418C5F19|rigid:wErOSSBb3zV40IzWQpOUBlUUHzs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PN40	uniprotkb:Q8N2S1	intact:EBI-2809979|uniprotkb:Q6KX48|uniprotkb:Q6I3D2|uniprotkb:E9QZ41|uniprotkb:E9QZ42|uniprotkb:Q81V48|uniprotkb:A0A0F7RLX2	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905.8	psi-mi:a0a6l8pn40_bacan(display_long)|uniprotkb:GBAA_0653(locus name)	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2809976|imex:IM-13779-1415	author score:9|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR052706|go:""GO:0016020""(membrane)|interpro:IPR036513|refseq:WP_000487882.1"	"ensembl:ENSG00000090006.18(gene)|ensembl:ENST00000308370.11(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006457""(protein folding)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031012""(extracellular matrix)|go:""GO:0046879""(hormone secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q8N2S1|reactome:R-HSA-2129379|reactome:R-HSA-2173789|refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|efo:""Orphanet:221145""|efo:""Orphanet:98896""|panther:PTHR24034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uXxKvpa5urYCow1J6WlFTe4Oxoo1392	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	intact-crc:80CDF11CB751A7E7|rigid:Mxwrj8SRUUUm6PfQod6dXi9jdiw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81UM1	uniprotkb:P09871	intact:EBI-2810062|uniprotkb:Q6KWM8|uniprotkb:E9QUN3	intact:EBI-2810045|uniprotkb:Q9UCU9|uniprotkb:Q9UCV3|uniprotkb:Q9UCU7|uniprotkb:Q9UCV5|uniprotkb:Q9UCV4|uniprotkb:Q9UCU8|uniprotkb:Q9UCV2|uniprotkb:Q9UCV1|uniprotkb:Q9UCV0|uniprotkb:Q9UM14|uniprotkb:D3DUT4|ensembl:ENSP00000328173.3|ensembl:ENSP00000354057.5|ensembl:ENSP00000385035.1	psi-mi:q81um1_bacan(display_long)|uniprotkb:GBAA_0843(locus name)	psi-mi:c1s_human(display_long)|uniprotkb:C1S(gene name)|psi-mi:C1S(display_short)|uniprotkb:C1 esterase(gene name synonym)|uniprotkb:Complement component 1 subcomponent s(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810059|imex:IM-13779-1420	author score:9|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018028|interpro:IPR010582(Catalase-related)|interpro:IPR024712|interpro:IPR020835|interpro:IPR002226(Catalase)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR043156|interpro:IPR029062|go:""GO:0004096""(catalase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0020037""(heme binding)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR041399"	"ensembl:ENSG00000182326.17(gene)|ensembl:ENST00000328916.7(transcript)|ensembl:ENST00000360817.10(transcript)|ensembl:ENST00000406697.5(transcript)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0072562""(blood microparticle)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR024175|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR043504|mint:P09871|rcsb pdb:1ELV|rcsb pdb:1NZI|rcsb pdb:4J1Y|rcsb pdb:4LMF|rcsb pdb:4LOR|rcsb pdb:4LOS|rcsb pdb:4LOT|rcsb pdb:6F1C|rcsb pdb:6F1H|rcsb pdb:8GMN|rcsb pdb:8TYP|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|refseq:NP_001333779.1|refseq:NP_001725.1|refseq:NP_958850.1|refseq:XP_005253817.1|efo:""Orphanet:169147""|efo:""Orphanet:75392""|panther:PTHR24255(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:emjR7zrszb3kjc9o/hpyL6qIl941392	rogid:3zz5RwIqLyPO71zdCp5Vx7aVl+Y9606	intact-crc:A1B5189BD4FD44F7|rigid:gDA1kDN8lI6tlQPt6cLnSMVcpJY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15700	uniprotkb:A0A6L8PW84	intact:EBI-80426|uniprotkb:Q59G57|uniprotkb:Q68CQ8|uniprotkb:Q6ZTA8|uniprotkb:B7WNY8|uniprotkb:F8W9V6|uniprotkb:Q5H9Q4|ensembl:ENSP00000381355.2	intact:EBI-2810036|uniprotkb:Q6I0D7|uniprotkb:Q6KUA7|uniprotkb:E9QSG5|uniprotkb:E9QSG6|uniprotkb:Q81S56|uniprotkb:A0A0F7RJG7	psi-mi:dlg2_human(display_long)|uniprotkb:DLG2(gene name)|psi-mi:DLG2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)	psi-mi:a0a6l8pw84_bacan(display_long)|uniprotkb:GBAA_1818(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810033|imex:IM-13779-1418	author score:9|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001355.2|refseq:NP_001136171.1|refseq:NP_001136172.1|refseq:NP_001136174.1|refseq:NP_001193698.1|panther:PTHR23119(orthology-group)|ensembl:ENSG00000150672.19(gene)|ensembl:ENST00000398309.6(transcript)|go:""GO:0004385""(guanylate kinase activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007399""(nervous system development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0035865""(cellular response to potassium ion)|go:""GO:0043005""(neuron projection)|go:""GO:0043113""(receptor clustering)|go:""GO:0043204""(perikaryon)|go:""GO:0044224""(juxtaparanode region of axon)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0097120""(receptor localization to synapse)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:0099642""(retrograde axonal protein transport)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313(""Membrane-associated guanylate kinase (MAGUK) scaffold protein"")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|interpro:IPR050614|mint:Q15700|rcsb pdb:2BYG|rcsb pdb:2HE2|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-6794361|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244"	"interpro:IPR002901(Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase)|interpro:IPR001119(S-layer homology region)|refseq:WP_000756001.1|interpro:IPR051465|go:""GO:0004040""(amidase activity)|go:""GO:0030115""(S-layer)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hBuRCYIzH2etGCJINoeHIYFGTrc9606	rogid:rvtlwru3355qXbTQawe6Hx/9UN01392	intact-crc:EB954768C3CEDE58|rigid:eM5d5kkZP/f82vodMyzWSDcbEIY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5VYS8	uniprotkb:A0A6L7H280	intact:EBI-2810086|uniprotkb:Q96N57|uniprotkb:Q658Z9|uniprotkb:Q8N5F0|uniprotkb:Q96NE8|uniprotkb:Q5H9T0|uniprotkb:Q9C0F2|uniprotkb:Q6MZJ3|uniprotkb:Q659A2|uniprotkb:Q5VYS5|uniprotkb:Q9H8M6|uniprotkb:Q5VYS7|ensembl:ENSP00000365130.3	intact:EBI-2810080|uniprotkb:Q6HWG1|uniprotkb:Q6KQK9|uniprotkb:E9R333|uniprotkb:E9R334|uniprotkb:A0A2P0HGI7|uniprotkb:Q81NA2	psi-mi:tut7_human(display_long)|uniprotkb:TUT7(gene name)|psi-mi:TUT7(display_short)|uniprotkb:HS2(gene name synonym)|uniprotkb:KIAA1711(gene name synonym)|uniprotkb:ZCCHC6(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 6(gene name synonym)	psi-mi:a0a6l7h280_bacan(display_long)|uniprotkb:hypF(gene name)|psi-mi:hypF(display_short)|uniprotkb:GBAA_3313(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810077|imex:IM-13779-1421	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001171988.1|refseq:NP_001172003.1|refseq:NP_078893.2|ensembl:ENSG00000083223.18(gene)|ensembl:ENST00000375963.8(transcript)|go:""GO:0001556""(oocyte maturation)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010586""(miRNA metabolic process)|go:""GO:0031054""(pre-miRNA processing)|go:""GO:0031123""(RNA 3'-end processing)|go:""GO:0035198""(miRNA binding)|go:""GO:0050265""(RNA uridylyltransferase activity)|go:""GO:0070569""(uridylyltransferase activity)|go:""GO:0071076""(obsolete RNA 3' uridylation)|go:""GO:0141008""(transposable element silencing by mRNA destabilization)|go:""GO:1990074""(polyuridylation-dependent mRNA catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036875|interpro:IPR043519|interpro:IPR045100|interpro:IPR054708|rcsb pdb:5W0B|rcsb pdb:5W0M|rcsb pdb:5W0N|rcsb pdb:5W0O|rcsb pdb:8OEF|rcsb pdb:8OPP|rcsb pdb:8OPS|rcsb pdb:8OPT|reactome:R-HSA-429947|reactome:R-HSA-9819196|reactome:R-HSA-9820865|refseq:NP_001317647.1|refseq:XP_016870619.1|refseq:XP_016870620.1|panther:PTHR12271(orthology-group)"	"refseq:WP_000755925.1|interpro:IPR001792(Acylphosphatase)|interpro:IPR017968|interpro:IPR004421(Hydrogenase maturation factor, HypF-type)|interpro:IPR017945|interpro:IPR006070(SUA5/yciO/yrdC, N-terminal)|interpro:IPR011125(Zinc finger, HypF-type)|interpro:IPR051060|interpro:IPR043129|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003998""(acylphosphatase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016743""(carboxyl- or carbamoyltransferase activity)|go:""GO:0016874""(ligase activity)|go:""GO:0051604""(protein maturation)|interpro:IPR055128|interpro:IPR036046|interpro:IPR041440"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7SZLc/DgsdZVQBnq8x5e2MCunyQ9606	rogid:NiJgcEgsdw62qLQJeO1ER4HUq4s1392	intact-crc:4DCA82D97A5B75B6|rigid:BT4qF58t8aJXd5DtyMON4HJk6MU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P53365	uniprotkb:A0A6L8PRN6	intact:EBI-638194|uniprotkb:D3DQT5|uniprotkb:B4E306|uniprotkb:B4DX86|ensembl:ENSP00000254584.2|ensembl:ENSP00000379998.3	intact:EBI-2809795|uniprotkb:Q6KT17|uniprotkb:E9QTD7|uniprotkb:Q81QV1	psi-mi:arfp2_human(display_long)|uniprotkb:ADP-ribosylation factor-interacting protein 2(gene name synonym)|uniprotkb:Partner of RAC1(gene name synonym)|uniprotkb:ARFIP2(gene name)|psi-mi:ARFIP2(display_short)|uniprotkb:POR1(gene name synonym)	psi-mi:a0a6l8prn6_bacan(display_long)|uniprotkb:GBAA_2314(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810070|imex:IM-13779-1419	author score:9|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229784.1|refseq:NP_036534.1|refseq:NP_001229785.1|refseq:XP_005252897.1|ensembl:ENSG00000132254.13(gene)|ensembl:ENST00000254584.6(transcript)|ensembl:ENST00000396777.8(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0001726""(ruffle)|go:""GO:0005525""(GTP binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031529""(ruffle organization)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0034497""(protein localization to phagophore assembly site)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0140090""(membrane curvature sensor activity)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|mint:P53365|rcsb pdb:1I49|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:4DCN|reactome:R-HSA-6811440|panther:PTHR12141(orthology-group)"	interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR024696|refseq:WP_000249923.1|interpro:IPR051768|interpro:IPR036689	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:q3QMUWlBIW82Szrv9jbMR6ikOZg9606	rogid:F/oxRKTzWTtfjzkNdzflVMqhX0s1392	intact-crc:BA7A2D630F7C0BEC|rigid:cviP4N3yrKMeUMOZvtJ4k0B3JC8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3A8V4	uniprotkb:Q6NUQ1	intact:EBI-2810133|uniprotkb:A0A1J9WG58|uniprotkb:Q6KWL8|uniprotkb:Q6I2T9|uniprotkb:E9RC14|uniprotkb:E9RC15|uniprotkb:Q81UL0|uniprotkb:A0A2B8HWP9	intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|ensembl:ENSP00000257700.2|intact:EBI-28981798	psi-mi:a0a6h3a8v4_bacan(display_long)|uniprotkb:sasP1(gene name)|psi-mi:sasP1(display_short)|uniprotkb:GBAA_0858(locus name)	psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810130|imex:IM-13779-1423	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001448(Small acid-soluble spore protein, alpha/beta type)|interpro:IPR018126|refseq:WP_000013338.1|interpro:IPR050847|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0006265""(DNA topological change)|interpro:IPR038300"	"ensembl:ENSG00000135249.8(gene)|ensembl:ENST00000257700.7(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0015031""(protein transport)|go:""GO:0060628""(regulation of ER to Golgi vesicle-mediated transport)|go:""GO:0070939""(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|mint:Q6NUQ1|reactome:R-HSA-6811434|refseq:NP_068749.3|efo:""Orphanet:464724""|dip:DIP-36477N|panther:PTHR13520(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:L0kfSsXpT8asMqUkNwqi8XwOx8s1392	rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606	intact-crc:A01D540719AC0317|rigid:WuoMPEOAN7Z+sr8ZnjQLIgANHsM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1W4N6	uniprotkb:Q8TEL6	intact:EBI-2810109|uniprotkb:Q6HZP7|uniprotkb:Q6KTN4|uniprotkb:E9RB38|uniprotkb:E9RB39|uniprotkb:Q81JF5|uniprotkb:A0A1Q4M120	intact:EBI-2559060|ensembl:ENSP00000252015.2|uniprotkb:Q96H82|uniprotkb:Q9UFS6|uniprotkb:Q9BVB8|uniprotkb:Q9H429|uniprotkb:E1P5Q1|uniprotkb:E1P5Q0	psi-mi:a0a4y1w4n6_bacan(display_long)|uniprotkb:GBAA_2075(locus name)	psi-mi:tp4ap_human(display_long)|uniprotkb:TRPC4AP(gene name)|psi-mi:TRPC4AP(display_short)|uniprotkb:C20orf188(gene name synonym)|uniprotkb:TRRP4AP(gene name synonym)|uniprotkb:Protein TAP1(gene name synonym)|uniprotkb:TNF-receptor ubiquitous scaffolding/signaling protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810106|imex:IM-13779-1422	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|refseq:WP_000226260.1|interpro:IPR050710|go:""GO:0016020""(membrane)|interpro:IPR036013"	"ensembl:ENSG00000100991.12(gene)|ensembl:ENST00000252015.3(transcript)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019902""(phosphatase binding)|go:""GO:0031464""(Cul4A-RING E3 ubiquitin ligase complex)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048820""(hair follicle maturation)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022162|mint:Q8TEL6|reactome:R-HSA-3295583|refseq:NP_056453.1|refseq:NP_955400.1|dip:DIP-42719N|panther:PTHR31743(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VCRnolV60wUvaHSf272liArehbc1392	rogid:fGdo0w+MT7OtbDJDS9/HAx6Y7XE9606	intact-crc:32FDBB7BD2F47E78|rigid:F0oa/YYciaeN4igWkDpkUEe3IUM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99961	uniprotkb:A0A0J1HYK7	intact:EBI-697911|uniprotkb:Q99668|uniprotkb:B4DRA1|uniprotkb:E7EVZ4|uniprotkb:M0QZV5|ensembl:ENSP00000269886.2	intact:EBI-2810121|uniprotkb:A0A1Q4M6L3|uniprotkb:Q6KMX1|uniprotkb:Q6HTN1|uniprotkb:E9RDY9|uniprotkb:E9RDZ0|uniprotkb:Q81M78|uniprotkb:A0A2A8KRL5	psi-mi:sh3g1_human(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym)	psi-mi:a0a0j1hyk7_bacan(display_long)|uniprotkb:GBAA_4374(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810118|imex:IM-13779-1424	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001186872.1|refseq:NP_003016.1|refseq:NP_001186873.1|ensembl:ENSG00000141985.9(gene)|ensembl:ENST00000269886.7(transcript)|go:""GO:0002102""(podosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007417""(central nervous system development)|go:""GO:0008289""(lipid binding)|go:""GO:0016191""(synaptic vesicle uncoating)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0042995""(cell projection)|go:""GO:0045296""(cadherin binding)|go:""GO:0070161""(anchoring junction)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|interpro:IPR050384|mint:Q99961|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|dip:DIP-29452N|panther:PTHR14167(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|refseq:WP_000590218.1|interpro:IPR050086|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015424""(ABC-type amino acid transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR030679"	"psi-mi:""MI:0469""(intact)"	crc64:6E5BE978BC955077	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606	rogid:e8UjREQwSQJCc8U3lwXxT91onVY1392	intact-crc:720072FDCAFB9316|rigid:jKkgN73T1YxGvclda7knhpV4pjA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3K3	uniprotkb:A0A2B6C300	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	intact:EBI-2810143|uniprotkb:Q6KUT4|uniprotkb:Q6I0X8|uniprotkb:E9RCT6|uniprotkb:E9RCT7|uniprotkb:Q81SP6|uniprotkb:A0A0J1HPY9	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	psi-mi:a0a2b6c300_bacan(display_long)|uniprotkb:GBAA_1600(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810148|imex:IM-13779-1425	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	refseq:WP_001235537.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	rogid:Ua4K5TlTRIz4klc72LsSB+owr4w1392	intact-crc:F714A9862B75333A|rigid:fW5ZrodmIAoYgukwDR99v5bGaJA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WUM4	uniprotkb:A0A6H3ACE8	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|ensembl:ENSP00000307387.3|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|intact:EBI-28983290|uniprotkb:C5MQH7|intact:EBI-10971645	intact:EBI-2810192|uniprotkb:Q6I1B5|uniprotkb:Q6KV62|uniprotkb:E9R9W5|uniprotkb:E9R9W6|uniprotkb:Q81T33|uniprotkb:A0A0F7RF59	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	psi-mi:a0a6h3ace8_bacan(display_long)|uniprotkb:GBAA_1456(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810197|imex:IM-13779-1429	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037506.2|ensembl:ENSG00000170248.15(gene)|ensembl:ENST00000307296.8(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0000915""(actomyosin contractile ring assembly)|go:""GO:0001772""(immunological synapse)|go:""GO:0005768""(endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006915""(apoptotic process)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0031871""(proteinase activated receptor binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0042470""(melanosome)|go:""GO:0042641""(actomyosin)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045199""(maintenance of epithelial cell apical/basal polarity)|go:""GO:0046755""(viral budding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0061952""(midbody abscission)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090543""(Flemming body)|go:""GO:0090559""(regulation of membrane permeability)|go:""GO:0090611""(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0097734""(extracellular exosome biogenesis)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903551""(regulation of extracellular exosome assembly)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001155901.1|refseq:NP_001243121.1|dip:DIP-29327N|panther:PTHR23030(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011712(Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR017202(Signal transduction histidine kinase, LiaS)|interpro:IPR050482|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0046983""(protein dimerization activity)|interpro:IPR036890|refseq:WP_000744313.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	rogid:QPB/y1kXKdQ3nVF/xNXQFN4ilhg1392	intact-crc:72EFABE3780D1188|rigid:JVi6XTkQptozBv0RMukxJ6Vk/CA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81LB8	uniprotkb:P12955	intact:EBI-2810158|uniprotkb:Q6HSS1|uniprotkb:Q6KM14	intact:EBI-948765|uniprotkb:Q8TBN9|uniprotkb:Q9BT75|uniprotkb:A8K3Z1|uniprotkb:A8K416|uniprotkb:A8K696|uniprotkb:A8MX47|uniprotkb:B4DGJ1|uniprotkb:B4DDB7|uniprotkb:E9PCE8|ensembl:ENSP00000244137.5	psi-mi:tig_bacan(display_long)|uniprotkb:tig(gene name)|psi-mi:tig(display_short)|uniprotkb:PPIase(gene name synonym)|uniprotkb:BAS4370(locus name)|uniprotkb:BA_4705(locus name)|uniprotkb:GBAA_4705(locus name)	psi-mi:pepd_human(display_long)|uniprotkb:Proline dipeptidase(gene name synonym)|uniprotkb:Imidodipeptidase(gene name synonym)|uniprotkb:Peptidase D(gene name synonym)|uniprotkb:PEPD(gene name)|psi-mi:PEPD(display_short)|uniprotkb:PRD(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810155|imex:IM-13779-1426	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR027304|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR005215(Trigger factor)|interpro:IPR008880(Trigger factor, C-terminal, bacterial)|interpro:IPR008881(Trigger factor, ribosome-binding, bacterial)|go:""GO:0005737""(cytoplasm)|go:""GO:0015031""(protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043335""(protein unfolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051301""(cell division)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|refseq:WP_000729253.1|interpro:IPR036611|interpro:IPR037041|refseq:NP_846918.1|refseq:YP_030617.1|interpro:IPR046357"	"dip:DIP-50038N|efo:""Orphanet:742""|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|ensembl:ENSG00000124299.16(gene)|ensembl:ENST00000244137.12(transcript)|go:""GO:0004181""(metallocarboxypeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0008233""(peptidase activity)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030574""(collagen catabolic process)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0102009""(proline dipeptidase activity)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|interpro:IPR029149|interpro:IPR036005|interpro:IPR052433|rcsb pdb:2IW2|rcsb pdb:2OKN|rcsb pdb:5M4G|rcsb pdb:5M4J|rcsb pdb:5M4L|rcsb pdb:5M4Q|rcsb pdb:5MBY|rcsb pdb:5MBZ|rcsb pdb:5MC0|rcsb pdb:5MC1|rcsb pdb:5MC2|rcsb pdb:5MC3|rcsb pdb:5MC4|rcsb pdb:5MC5|rcsb pdb:6H2P|rcsb pdb:6H2Q|rcsb pdb:6QSB|rcsb pdb:6QSC|rcsb pdb:6SRE|rcsb pdb:6SRF|rcsb pdb:6SRG|refseq:NP_000276.2|refseq:NP_001159528.1|refseq:NP_001159529.1|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	crc64:E8C4A2497E44BA22	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AXRPk6I10MtZssV4TGaiiOnZ0/o1392	rogid:S33ZGUuOs+AAE83dREDwbnMKJws9606	intact-crc:F401DCD4E2304540|rigid:vPpkdiRspQmVxMI1LzdCyPQLGxI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00151	uniprotkb:A0A6L7HQ21	intact:EBI-724897|uniprotkb:Q5VZH5|uniprotkb:Q9BPZ9|uniprotkb:B2RBS6|ensembl:ENSP00000360305.3	intact:EBI-2810168|uniprotkb:Q6KKD6|uniprotkb:Q6HR17|uniprotkb:E9RBH1|uniprotkb:E9RBH2|uniprotkb:Q81X81|uniprotkb:A0A0F7RAW7	psi-mi:pdli1_human(display_long)|uniprotkb:Elfin(gene name synonym)|uniprotkb:LIM domain protein CLP-36(gene name synonym)|uniprotkb:C-terminal LIM domain protein 1(gene name synonym)|uniprotkb:PDLIM1(gene name)|psi-mi:PDLIM1(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:CLP36(gene name synonym)	psi-mi:a0a6l7hq21_bacan(display_long)|uniprotkb:GBAA_5361(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810173|imex:IM-13779-1428	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066272.1|ensembl:ENSG00000107438.9(gene)|ensembl:ENST00000329399.7(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001725""(stress fiber)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003779""(actin binding)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007507""(heart development)|go:""GO:0010761""(fibroblast migration)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030950""(establishment or maintenance of actin cytoskeleton polarity)|go:""GO:0031941""(filamentous actin)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0051371""(muscle alpha-actinin binding)|go:""GO:0061061""(muscle structure development)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR028537|interpro:IPR031847|interpro:IPR036034|interpro:IPR050604|mint:O00151|rcsb pdb:1X62|rcsb pdb:2PKT|panther:PTHR24214(orthology-group)"	interpro:IPR024455|interpro:IPR054612|refseq:WP_000168836.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kUUqX2NgmaXbdbESj6oHxE+EQ2g9606	rogid:hBmvFWa1O4yKv9+ncHGD9WU2vYw1392	intact-crc:9A8568A2DA4190BB|rigid:IunxBc14Iv6V15NW+YDiQxnIHdU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30101	uniprotkb:A0A6L7HD40	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289.5	intact:EBI-2810183|uniprotkb:Q6KLQ3|uniprotkb:E9QSB9|uniprotkb:Q81L02|uniprotkb:A0A0F7RB54	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	psi-mi:a0a6l7hd40_bacan(display_long)|uniprotkb:phoR(gene name)|psi-mi:phoR(display_short)|uniprotkb:GBAA_4832(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810180|imex:IM-13779-1427	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000167004.14(gene)|ensembl:ENST00000300289.10(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004629""(phospholipase C activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0009986""(cell surface)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061779""(Tapasin-ERp57 complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|rcsb pdb:7QNG|rcsb pdb:7QPD|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|refseq:NP_005304.3|dip:DIP-29132N|panther:PTHR18929(orthology-group)"	"interpro:IPR031967|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|refseq:WP_001032128.1|interpro:IPR050351|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016036""(cellular response to phosphate starvation)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	rogid:qJyafQ+ueTkNv1tskYoeZbePYzc1392	intact-crc:6A1A7F996E67039D|rigid:YfyCpTMLEQMxkDNNAkwtto25Xms	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81MI9	uniprotkb:P17931	intact:EBI-2810228|uniprotkb:Q6HTY9|uniprotkb:Q6KN69	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	"psi-mi:mtnd_bacan(display_long)|uniprotkb:mtnD(gene name)|psi-mi:mtnD(display_short)|uniprotkb:1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(gene name synonym)|uniprotkb:""Acireductone dioxygenase (Fe(2+)-requiring)""(gene name synonym)|uniprotkb:""Acireductone dioxygenase (Ni(2+)-requiring)""(gene name synonym)|uniprotkb:BA_4258(locus name)|uniprotkb:GBAA_4258(locus name)|uniprotkb:BAS3949(locus name)"	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810234|imex:IM-13779-1431	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023956|interpro:IPR004313(Acireductone dioxygenase, ARD)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|go:""GO:0005506""(iron ion binding)|go:""GO:0010308""(""acireductone dioxygenase (Ni2+-requiring) activity"")|go:""GO:0010309""(""acireductone dioxygenase [iron(II)-requiring] activity"")|go:""GO:0016151""(nickel cation binding)|go:""GO:0019284""(L-methionine salvage from S-adenosylmethionine)|go:""GO:0019509""(L-methionine salvage from methylthioadenosine)|rcsb pdb:4QGL|rcsb pdb:4QGM|refseq:WP_000057328.1|refseq:NP_846493.1|refseq:YP_030199.1"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:8qcvDO73KtNm6kcTYXSdmY/sJhw1392	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:BA50F6ED4499B563|rigid:yiVR52VhSmjyus3XHg7QFma1Zjo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96RW7	uniprotkb:A0A6L8PBE8	intact:EBI-2806183|uniprotkb:Q96DN8|uniprotkb:Q5TYR7|uniprotkb:Q96DN3|uniprotkb:Q96SC3|uniprotkb:A6NGE3|ensembl:ENSP00000271588.4	intact:EBI-2810254|uniprotkb:Q6KWK3|uniprotkb:Q6I2S2|uniprotkb:E9QWW6|uniprotkb:E9QWW7|uniprotkb:Q81UJ3|uniprotkb:A0A0F7RLP7	psi-mi:hmcn1_human(display_long)|uniprotkb:FIBL6(gene name synonym)|uniprotkb:Fibulin-6(gene name synonym)|uniprotkb:HMCN1(gene name)|psi-mi:HMCN1(display_short)	psi-mi:a0a6l8pbe8_bacan(display_long)|uniprotkb:GBAA_0876(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810259|imex:IM-13779-1432	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_114141.2|refseq:XP_011508340.1|ensembl:ENSG00000143341.12(gene)|ensembl:ENST00000271588.9(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005737""(cytoplasm)|go:""GO:0005912""(adherens junction)|go:""GO:0005927""(muscle tendon junction)|go:""GO:0005938""(cell cortex)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007601""(visual perception)|go:""GO:0009617""(response to bacterium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0051301""(cell division)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071711""(basement membrane organization)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018097|interpro:IPR026823|interpro:IPR036179|interpro:IPR036383|interpro:IPR036465|interpro:IPR049883|interpro:IPR050958|panther:PTHR23277(orthology-group)"	"interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR025110|go:""GO:0003824""(catalytic activity)|interpro:IPR050237|interpro:IPR042099|interpro:IPR045851|refseq:WP_000282022.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hybxCgCN8p6aJ6LoTgeKIfTQzYA9606	rogid:Z5sCT05VbUe0hkm9GioLEacM3ps1392	intact-crc:FC54641392CD8278|rigid:cxkjFmk42b7kJhc6UP4jEYGq8Rg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q81S27	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2810215|uniprotkb:Q6I0A6|uniprotkb:Q6KU80	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:ilvc2_bacan(display_long)|uniprotkb:ilvC2(gene name)|psi-mi:ilvC2(display_short)|uniprotkb:ilvC-2(gene name synonym)|uniprotkb:Acetohydroxy-acid isomeroreductase 2(gene name synonym)|uniprotkb:BA_1852(locus name)|uniprotkb:GBAA_1852(locus name)|uniprotkb:BAS1716(locus name)|uniprotkb:Alpha-keto-beta-hydroxylacyl reductoisomerase 2(gene name synonym)|uniprotkb:Ketol-acid reductoisomerase type 1(gene name synonym)|uniprotkb:Ketol-acid reductoisomerase type I(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810221|imex:IM-13779-1433	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013023(Acetohydroxy acid isomeroreductase)|interpro:IPR000506(Acetohydroxy acid isomeroreductase C-terminal)|interpro:IPR013116(Acetohydroxy acid isomeroreductase, catalytic)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004455""(ketol-acid reductoisomerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0050661""(NADP binding)|refseq:WP_000861162.1|interpro:IPR014359(Ketol-acid reductoisomerase, gammaproteobacteria)|interpro:IPR036291|refseq:NP_844269.1|refseq:YP_027981.1|rcsb pdb:8EP7"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:GBngyk+IvD+ZNENclr7Vr+WEkFs1392	intact-crc:5D7FBC00798186BB|rigid:NYAEDOBNdRaSVkbsZrcopcR9nb8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P55209	uniprotkb:A0A6L8PH40	intact:EBI-356392|uniprotkb:B3KNT8|ensembl:ENSP00000376947.3|ensembl:ENSP00000477538.1|uniprotkb:B3KV44|intact:EBI-21355522	intact:EBI-2810204|uniprotkb:Q6KQ50|uniprotkb:E9RDQ6|uniprotkb:A0A2P0HGN2|uniprotkb:Q81YP2	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:a0a6l8ph40_bacan(display_long)|uniprotkb:GBAA_3497(locus name)|uniprotkb:hcp(gene name)|psi-mi:hcp(display_short)|uniprotkb:Hybrid-cluster protein(gene name synonym)|uniprotkb:Prismane protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810208|imex:IM-13779-1430	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004528.1|refseq:NP_631946.1|ensembl:ENSG00000187109.15(gene)|ensembl:ENST00000393263.7(transcript)|ensembl:ENST00000618691.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0042393""(histone binding)|go:""GO:0042470""(melanosome)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0140713""(histone chaperone activity)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|interpro:IPR002164(""Nucleosome assembly protein (NAP)"")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|rcsb pdb:7UN3|rcsb pdb:7UN6|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|panther:PTHR11875(orthology-group)"	"interpro:IPR010048(Hybrid cluster protein)|interpro:IPR004137(Prismane)|interpro:IPR011254(Prismane-like)|interpro:IPR016099(Prismane-like, alpha/beta-sandwich)|interpro:IPR016100(Prismane, alpha-bundle)|go:""GO:0004601""(peroxidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0046872""(metal ion binding)|go:""GO:0050418""(hydroxylamine reductase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_000458880.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rogid:N9ZuOG215ykhbNBBpX5HpQbk8dw1392	intact-crc:2045C2EDA58305D8|rigid:H7j9YmQrZOINf7gUkIa9gJS5+fg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81L32	uniprotkb:Q07666	intact:EBI-2810244|uniprotkb:Q6HSI7|uniprotkb:Q6KLT2	intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829.7	psi-mi:syn_bacan(display_long)|uniprotkb:asnS(gene name)|psi-mi:asnS(display_short)|uniprotkb:Asparaginyl-tRNA synthetase(gene name synonym)|uniprotkb:BAS4454(locus name)|uniprotkb:BA_4802(locus name)|uniprotkb:GBAA_4802(locus name)	psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810241|imex:IM-13779-1434	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004522(Asparaginyl-tRNA synthetase, class IIb)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0004816""(asparagine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006421""(asparaginyl-tRNA aminoacylation)|go:""GO:0016740""(transferase activity)|refseq:WP_000432163.1|refseq:NP_847005.1|refseq:YP_030701.1|interpro:IPR045864"	"refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|panther:PTHR11208(orthology-group)|ensembl:ENSG00000121774.18(gene)|ensembl:ENST00000327300.12(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0016020""(membrane)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046831""(regulation of RNA export from nucleus)|go:""GO:0046833""(positive regulation of RNA export from nucleus)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070618""(Grb2-Sos complex)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|interpro:IPR045071|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|rcsb pdb:7Z89|rcsb pdb:7Z8A|rcsb pdb:7Z9A|rcsb pdb:7Z9B|rcsb pdb:7ZAB|rcsb pdb:7ZAC|rcsb pdb:7ZAF|rcsb pdb:7ZAM|reactome:R-HSA-8849468"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:mt3LZ6UiTSkQu3DvSutGoRSLUGM1392	rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606	intact-crc:8B7FDFA8FBB51C09|rigid:lro2YMF6qyhNjW6qJedbkhxCcyc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AKT1	uniprotkb:Q14192	intact:EBI-2810296|uniprotkb:Q6KMD5|uniprotkb:Q6HT47|uniprotkb:E9QUJ5|uniprotkb:E9QUJ6|uniprotkb:Q81LP0|uniprotkb:A0A2B6BPP5	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	psi-mi:a0a6h3akt1_bacan(display_long)|uniprotkb:GBAA_4573(locus name)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810293|imex:IM-13779-1435	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001201016.1	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:+5AdnRZPIAeI4thFVeE4zG2Rctc1392	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:92E391A2378621D5|rigid:WBZjzLN9UNROJVaigMqWw1BfZGY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81TT4	uniprotkb:Q96NT0	intact:EBI-2810319|uniprotkb:Q6KVV5|uniprotkb:Q6I218	intact:EBI-2810325|uniprotkb:Q9BR88|ensembl:ENSP00000259229.2|uniprotkb:B4DJ47	psi-mi:clpb_bacan(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:BA_1177(locus name)|uniprotkb:GBAA_1177(locus name)|uniprotkb:BAS1090(locus name)	psi-mi:cc115_human(display_long)|uniprotkb:CCDC115(gene name)|psi-mi:CCDC115(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810330|imex:IM-13779-1436	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR050130|interpro:IPR027417|interpro:IPR028299|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034605""(cellular response to heat)|go:""GO:0042026""(protein refolding)|refseq:WP_000365381.1|interpro:IPR036628|interpro:IPR041546|refseq:NP_843655.1|refseq:YP_027362.1"	"ensembl:ENSG00000136710.10(gene)|ensembl:ENST00000259229.7(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0016020""(membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070072""(vacuolar proton-transporting V-type ATPase complex assembly)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR040357|mint:Q96NT0|reactome:R-HSA-8980692|refseq:NP_001308047.1|refseq:NP_001308048.1|refseq:NP_115733.2|efo:""Orphanet:468684""|panther:PTHR31996(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RwqOsWdy9S7sYBI7SYTY7Mv0pSE1392	rogid:cUCb36pVMieoV7ZwXQPtD/kIAXY9606	intact-crc:D7FDA79BA26825ED|rigid:f2ZmKfKg1LNTcmbIwqNe1DE0FmU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z4H7	uniprotkb:A0A4Y1WE58	intact:EBI-2558196|uniprotkb:Q05CG1|uniprotkb:Q14CB6|uniprotkb:Q2TA91|uniprotkb:Q8IZQ4|uniprotkb:Q9H998|uniprotkb:Q96FN0|uniprotkb:Q14CD9|uniprotkb:B3KPK4|uniprotkb:Q6IQ10|uniprotkb:Q9H950|uniprotkb:Q9NXT8|uniprotkb:Q9HCJ8|uniprotkb:Q6NZX5|uniprotkb:B4DX82|ensembl:ENSP00000369871.3	intact:EBI-2810305|uniprotkb:Q6KW20|uniprotkb:Q6I285|uniprotkb:E9R1F6|uniprotkb:E9R1F7|uniprotkb:A0A2P0HB60|uniprotkb:Q81U00	psi-mi:haus6_human(display_long)|uniprotkb:HAUS6(gene name)|psi-mi:HAUS6(display_short)|uniprotkb:DGT6(gene name synonym)|uniprotkb:FAM29A(gene name synonym)|uniprotkb:KIAA1574(gene name synonym)	psi-mi:a0a4y1we58_bacan(display_long)|uniprotkb:GBAA_1094(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810312|imex:IM-13779-1438	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060115.3|refseq:NP_001257819.1|dip:DIP-48830N|ensembl:ENSG00000147874.11(gene)|ensembl:ENST00000380502.8(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007098""(centrosome cycle)|go:""GO:0008017""(microtubule binding)|go:""GO:0010968""(regulation of microtubule nucleation)|go:""GO:0051225""(spindle assembly)|go:""GO:0051301""(cell division)|go:""GO:0070652""(HAUS complex)|go:""GO:1990498""(mitotic spindle microtubule)|interpro:IPR026797|interpro:IPR028163|mint:Q7Z4H7|rcsb pdb:7SQK|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|panther:PTHR16151(orthology-group)"	"interpro:IPR020968|interpro:IPR008979(Galactose-binding like)|interpro:IPR022385|interpro:IPR006530(YD repeat)|interpro:IPR050708|go:""GO:0016020""(membrane)|refseq:WP_000387561.1|interpro:IPR045351|interpro:IPR031325"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:l5edu15aLS4hXrPg/lfQ2323G2o9606	rogid:8jqYn7kracNCDGYibTeEcZe2fl81392	intact-crc:DD06A41A7092B6CE|rigid:edNjLTcLfx7aK59iN+ZuGPEsp8s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2H6	uniprotkb:A0A6L8PRT3	intact:EBI-2810266|uniprotkb:Q6EVH4|uniprotkb:Q6N020|uniprotkb:B4DYG1|uniprotkb:Q5JVF8|uniprotkb:Q5HYC9|uniprotkb:Q6ZME4|uniprotkb:Q6P9D5|uniprotkb:Q6EVH3|uniprotkb:Q5JVF9|uniprotkb:Q9H1W1|ensembl:ENSP00000417257.1|ensembl:ENSP00000441831.1	intact:EBI-2810281|uniprotkb:Q6KWF0|uniprotkb:Q6I2L9|uniprotkb:E9QYR1|uniprotkb:E9QYR2|uniprotkb:A0A2P0HAS7|uniprotkb:Q81UD8	psi-mi:fnd3a_human(display_long)|uniprotkb:FNDC3A(gene name)|psi-mi:FNDC3A(display_short)|uniprotkb:FNDC3(gene name synonym)|uniprotkb:HUGO(gene name synonym)|uniprotkb:KIAA0970(gene name synonym)|uniprotkb:Human gene expressed in odontoblasts(gene name synonym)	psi-mi:a0a6l8prt3_bacan(display_long)|uniprotkb:GBAA_0939(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810286|imex:IM-13779-1437	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001073141.1|refseq:NP_055738.3|refseq:XP_011533299.1|refseq:NP_001265367.1|ensembl:ENSG00000102531.16(gene)|ensembl:ENST00000492622.6(transcript)|ensembl:ENST00000541916.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007286""(spermatid development)|go:""GO:0009566""(fertilization)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060009""(Sertoli cell development)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR050617|mint:Q9Y2H6|rcsb pdb:1WK0|rcsb pdb:1X3D|rcsb pdb:1X4X|rcsb pdb:1X5X|rcsb pdb:2CRM|rcsb pdb:2CRZ|refseq:XP_016875929.1|refseq:XP_016875930.1|refseq:XP_016875931.1|panther:PTHR24099(orthology-group)"	"interpro:IPR002781(Protein of unknown function DUF81)|interpro:IPR052017|go:""GO:0005886""(plasma membrane)|refseq:WP_000348431.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7gFZgxAfa590PH85SnEF3oeSNSI9606	rogid:mPVMar2OZMt09C2nspk5UtS2Voo1392	intact-crc:6A45E6A9FF918AAD|rigid:eOwrtA10zztRtZI+pIlmZKB+vdc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TAQ2	uniprotkb:A0A6L8NXL2	intact:EBI-357418|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3|ensembl:ENSP00000267064.4	intact:EBI-2810373|uniprotkb:Q6HSY9|uniprotkb:E9R1I8|uniprotkb:Q6KM77	psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym)	"psi-mi:a0a6l8nxl2_bacan(display_long)|uniprotkb:relA(gene name)|psi-mi:relA(display_short)|uniprotkb:GBAA_4637(locus name)|uniprotkb:""ATP:GTP 3'-pyrophosphotransferase""(gene name synonym)|uniprotkb:ppGpp synthase I(gene name synonym)|uniprotkb:""(p)ppGpp synthase""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810378|imex:IM-13779-1440	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1465""|ensembl:ENSG00000139613.12(gene)|ensembl:ENST00000267064.8(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006337""(nucleosome disassembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007399""(nervous system development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035060""(brahma complex)|go:""GO:0042393""(histone binding)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0071564""(npBAF complex)|go:""GO:0071565""(nBAF complex)|go:""GO:0140092""(bBAF complex)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR049898|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7VDV|rcsb pdb:7Y8R|reactome:R-HSA-3214858|reactome:R-HSA-8939243|reactome:R-HSA-9824585|reactome:R-HSA-9845323|refseq:NP_001123892.1|refseq:NP_001317217.1|refseq:NP_003066.2|refseq:NP_620706.1|dip:DIP-27611N|panther:PTHR12802(orthology-group)"	"interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR043519|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR007685(RelA/SpoT)|interpro:IPR004811(RelA/SpoT protein)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|go:""GO:0003723""(RNA binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0008728""(GTP diphosphokinase activity)|go:""GO:0015970""(guanosine tetraphosphate biosynthetic process)|interpro:IPR033655|refseq:WP_001262816.1|interpro:IPR045600|interpro:IPR045865"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606	rogid:Q+seJPIrvTNL33DE6phHj8HuFUw1392	intact-crc:A86E95C130A7389A|rigid:GcI6PG2Mmhks5XDHDhn4ADU4A4U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:A0A1J9WBB5	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2810337|uniprotkb:Q6HT57|uniprotkb:Q6KME6|uniprotkb:A0A1J9WM20|uniprotkb:E9R3U9|uniprotkb:E9R3V0|uniprotkb:Q81LQ0|uniprotkb:A0A0J1HXZ1	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:a0a1j9wbb5_bacan(display_long)|uniprotkb:GBAA_4562(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810343|imex:IM-13779-1441	author score:8|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR019988|interpro:IPR050896|interpro:IPR006073(GTP1/OBG)|rcsb pdb:3H2Y|interpro:IPR027417|go:""GO:0005525""(GTP binding)|interpro:IPR030378|refseq:WP_000140795.1|interpro:IPR048422"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:wuQsMXSKOY+78AkuVWoxuxfVKik1392	intact-crc:FADDF1108FE00EE5|rigid:WEJLEC1HVUQGI8hX/Hu/hdiNYHY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HRI8	uniprotkb:Q14765	intact:EBI-2810366|uniprotkb:Q6F051	intact:EBI-1186538|uniprotkb:Q96NZ6|ensembl:ENSP00000351255.4|ensembl:ENSP00000376134.2|ensembl:ENSP00000412397.2|ensembl:ENSP00000414322.2	psi-mi:a0a6l7hri8_bacan(display_long)|uniprotkb:GBAA_pXO2_0034(locus name)	psi-mi:stat4_human(display_long)|uniprotkb:STAT4(gene name)|psi-mi:STAT4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810363|imex:IM-13779-1442	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_000249505.1"	"panther:PTHR11801(orthology-group)|ensembl:ENSG00000138378.20(gene)|ensembl:ENST00000358470.8(transcript)|dip:DIP-39854N|ensembl:ENST00000392320.7(transcript)|ensembl:ENST00000432798.2(transcript)|ensembl:ENST00000450994.2(transcript)|go:""GO:0000785""(chromatin)|efo:""Orphanet:117""|efo:""Orphanet:536""|efo:""Orphanet:85408""|efo:""Orphanet:85410""|efo:""Orphanet:93552""|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006952""(defense response)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0035722""(interleukin-12-mediated signaling pathway)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045063""(T-helper 1 cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070741""(response to interleukin-6)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR029839|interpro:IPR035856|interpro:IPR036535|interpro:IPR036860|interpro:IPR046991|interpro:IPR048988|mint:Q14765|reactome:R-HSA-8854691|reactome:R-HSA-8950505|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020958|refseq:NP_001230764.1|refseq:NP_003142.1|refseq:XP_006712782.1|refseq:XP_011510007.1|ensembl:ENSP00000351255.4|ensembl:ENSP00000376134.2|ensembl:ENSP00000414322.2|ensembl:ENSP00000412397.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CttsAiL8z2LvYlOUlkIGYJ7cxoA1392	rogid:z6Wvolbix1XQBOsVA/MIxXi56qU9606	intact-crc:8FE50469A65260DD|rigid:5mm3ODzqgqn54m7V12nPt6aqr0U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WF3	uniprotkb:Q9Y2Z4	intact:EBI-2810353|uniprotkb:Q6KNT6|uniprotkb:Q6HUK1	intact:EBI-1049286|uniprotkb:Q9H817|uniprotkb:D3DUW8|ensembl:ENSP00000320658.8	psi-mi:pyrk_bacan(display_long)|uniprotkb:pyrK(gene name)|psi-mi:pyrK(display_short)|uniprotkb:Dihydroorotate oxidase B, electron transfer subunit(gene name synonym)|uniprotkb:BAS3736(locus name)|uniprotkb:BA_4024(locus name)|uniprotkb:GBAA_4024(locus name)	psi-mi:syym_human(display_long)|uniprotkb:YARS2(gene name)|psi-mi:YARS2(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:CGI-04(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810350|imex:IM-13779-1439	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012165(Cytochrome-c3 hydrogenase, gamma subunit)|interpro:IPR019480|interpro:IPR017927|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR017938|interpro:IPR050353|interpro:IPR023455|go:""GO:0009055""(electron transfer activity)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|refseq:WP_000983358.1|interpro:IPR037117|interpro:IPR039261|refseq:NP_846265.1|refseq:YP_029987.1"	"ensembl:ENSG00000139131.13(gene)|ensembl:ENST00000324868.13(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004831""(tyrosine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0016604""(nuclear body)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043039""(tRNA aminoacylation)|go:""GO:0070184""(mitochondrial tyrosyl-tRNA aminoacylation)|go:""GO:0072545""(L-tyrosine binding)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR024088|interpro:IPR036986|mint:Q9Y2Z4|rcsb pdb:2PID|rcsb pdb:3ZXI|reactome:R-HSA-379726|refseq:NP_001035526.1|dip:DIP-29487N|efo:""Orphanet:2598""|panther:PTHR11766(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:ukHmn2WCGQnyGSMWOj4GYa3bqC81392	rogid:cTNOZVenqyzWUlHTF7XLcZIKV+s9606	intact-crc:D46CCC88237F20BB|rigid:EAWVi6msehjUfLM/SZvB+KrG+70	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HA92	uniprotkb:A0A6L7H2Q9	intact:EBI-2810392|uniprotkb:Q9BRY7|uniprotkb:Q86VC4|uniprotkb:Q53HV8|uniprotkb:Q9NUS7|ensembl:ENSP00000258955.2|uniprotkb:B4DMW0	intact:EBI-2810400|uniprotkb:Q6KTQ9|uniprotkb:Q6HZS4|uniprotkb:E9RAZ3|uniprotkb:E9RAZ4|uniprotkb:Q81RJ7|uniprotkb:A0A0F7RD30	psi-mi:rsad1_human(display_long)|uniprotkb:RSAD1(gene name)|psi-mi:RSAD1(display_short)|uniprotkb:Putative heme chaperone(gene name synonym)	psi-mi:a0a6l7h2q9_bacan(display_long)|uniprotkb:GBAA_2047(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810405|imex:IM-13779-1443	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060816.1|ensembl:ENSG00000136444.10(gene)|ensembl:ENST00000258955.7(transcript)|go:""GO:0004109""(coproporphyrinogen oxidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006779""(porphyrin-containing compound biosynthetic process)|go:""GO:0020037""(heme binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR004559(Putative oxygen-independent coproporphyrinogen III oxidase)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR010723(HemN, C-terminal)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR034505|panther:PTHR13932(orthology-group)"	interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:WP_000216920.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LruAJaa5xrnTP8+R+8CyOF5lOu09606	rogid:H+yb15aOHMi9sIfuMqerdtx927Y1392	intact-crc:0B69E4DAA9B0459B|rigid:Q4u/Ei1wVH5xG4vY3wyz0FJAnRY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7RE19	uniprotkb:O94979	intact:EBI-2809783|uniprotkb:Q6KPM6|uniprotkb:Q6HVF7|uniprotkb:E9QS28|uniprotkb:E9QS29|uniprotkb:Q81Y62	intact:EBI-1767898|uniprotkb:Q17RR5|uniprotkb:Q5H9P6|uniprotkb:Q5XG74|uniprotkb:Q659G7|uniprotkb:Q6ZU90|uniprotkb:Q7LCX9|uniprotkb:Q86TJ0|uniprotkb:Q8IZH4|uniprotkb:Q9P048|uniprotkb:Q9P0A6|uniprotkb:Q9UM05|uniprotkb:Q9UM06|uniprotkb:B7ZKZ7|intact:EBI-25605813|uniprotkb:B7ZL00|uniprotkb:B4DIW6|uniprotkb:H7C2W3|ensembl:ENSP00000347329.2|ensembl:ENSP00000378721.2|ensembl:ENSP00000400926.1	psi-mi:a0a0f7re19_bacan(display_long)|uniprotkb:GBAA_3695(locus name)	psi-mi:sc31a_human(display_long)|uniprotkb:SEC31A(gene name)|psi-mi:SEC31A(display_short)|uniprotkb:KIAA0905(gene name synonym)|uniprotkb:SEC31L1(gene name synonym)|uniprotkb:HSPC275(orf name)|uniprotkb:HSPC334(orf name)|uniprotkb:SEC31-related protein A(gene name synonym)|uniprotkb:SEC31-like protein 1(gene name synonym)|uniprotkb:ABP125(gene name synonym)|uniprotkb:ABP130(gene name synonym)|uniprotkb:Web1-like protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810385|imex:IM-13779-1445	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001119(S-layer homology region)|interpro:IPR051465|go:""GO:0030115""(S-layer)|interpro:IPR032247"	"refseq:NP_001070674.1|refseq:NP_001070675.1|refseq:NP_001070676.1|refseq:NP_057295.2|refseq:NP_001177978.1|refseq:NP_001287673.1|refseq:NP_001287674.1|refseq:NP_001305048.1|refseq:NP_001305049.1|dip:DIP-40438N|ensembl:ENSG00000138674.17(gene)|ensembl:ENST00000355196.6(transcript)|ensembl:ENST00000395310.7(transcript)|ensembl:ENST00000448323.5(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0015031""(protein transport)|go:""GO:0030120""(vesicle coat)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024298|interpro:IPR036322|interpro:IPR040251|mint:O94979|rcsb pdb:3WXA|rcsb pdb:7SUL|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-381038|reactome:R-HSA-9725370|reactome:R-HSA-983170|panther:PTHR13923(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RZeq/OQN8n8nnEe280+/uO/FFX01392	rogid:MvtQi/4RmQ0siNtNoYH6k1rPv1Y9606	intact-crc:89571D234B67AB80|rigid:chaHTCnzMGVoC8dswi2sSRTO5eg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5R372	uniprotkb:A0A3Q0PRD7	intact:EBI-2810417|uniprotkb:Q8WV78|uniprotkb:Q9UQP5|uniprotkb:Q5R369|uniprotkb:Q9UQ19|uniprotkb:Q8N921|uniprotkb:O75059|uniprotkb:Q3ZTR8|uniprotkb:Q9Y6Y5|uniprotkb:Q9NSP8|uniprotkb:Q8IVV0|intact:EBI-3203909|uniprotkb:Q9Y6Y6|ensembl:ENSP00000251507.4	intact:EBI-2810412|uniprotkb:Q6KSP1|uniprotkb:Q6HYP0|uniprotkb:A0A1T3V4S0|uniprotkb:E9R444|uniprotkb:E9R445|uniprotkb:Q81QG7	psi-mi:rbg1l_human(display_long)|uniprotkb:RABGAP1L(gene name)|psi-mi:RABGAP1L(display_short)|uniprotkb:HHL(gene name synonym)|uniprotkb:KIAA0471(gene name synonym)	psi-mi:a0a3q0prd7_bacan(display_long)|uniprotkb:GBAA_2458(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810432|imex:IM-13779-1446	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001030307.1|refseq:NP_055672.3|refseq:NP_001230692.1|refseq:NP_001230694.1|ensembl:ENSG00000152061.24(gene)|ensembl:ENST00000251507.8(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006897""(endocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032880""(regulation of protein localization)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022164|interpro:IPR035969|interpro:IPR050302|rcsb pdb:3HZJ|panther:PTHR47219(orthology-group)"	interpro:IPR008863(Toxic anion resistance)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cvAqfETiY1zUH+PVyBtdzMuOPD09606	rogid:yFhxdvzsJZtdS3cPPgkYzGM4tvA1392	intact-crc:A7A196199666C8E0|rigid:85rnSpTOLRKLL69FC6c6Y/r0olI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NXJ9	uniprotkb:Q81X77	intact:EBI-2810445	intact:EBI-2810439|uniprotkb:Q6HR13|uniprotkb:Q6KKD2	psi-mi:q9nxj9_human(display_long)	psi-mi:gpmi_bacan(display_long)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)|uniprotkb:gpmA(gene name synonym)|uniprotkb:BA_5365(locus name)|uniprotkb:GBAA_5365(locus name)|uniprotkb:BAS4986(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810448|imex:IM-13779-1444	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR052435|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR036600|interpro:IPR049257"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|rcsb pdb:2IFY|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030435""(sporulation resulting in formation of a cellular spore)|go:""GO:0043937""(regulation of sporulation)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|refseq:WP_001231153.1|interpro:IPR036646|refseq:NP_847539.1|refseq:YP_031225.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eIwM1L2dR2qDXLwN2StvefxgHu49606	rogid:pxX2Dycc6/EBhmFHPZ5uVcHE6I41392	intact-crc:3AFE251B16B637D9|rigid:jQVSGm4e+l8GH3y+DdBSzQCSWmM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HR87	uniprotkb:Q96BD5	intact:EBI-2810473|uniprotkb:Q6KY70|uniprotkb:Q6I4G9|uniprotkb:E9QXF3|uniprotkb:E9QXF4|uniprotkb:Q81VG6|uniprotkb:A0A1S0QS93	intact:EBI-745085|uniprotkb:Q6AWA2|uniprotkb:Q9C0G7|uniprotkb:Q9H8V9|uniprotkb:Q9HAK6|uniprotkb:Q9NZE9|uniprotkb:D3DQP5|ensembl:ENSP00000398824.2	psi-mi:a0a6l7hr87_bacan(display_long)|uniprotkb:hppD(gene name)|psi-mi:hppD(display_short)|uniprotkb:GBAA_0240(locus name)	psi-mi:pf21a_human(display_long)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810479|imex:IM-13779-1447	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005956(4-hydroxyphenylpyruvate dioxygenase)|interpro:IPR004360(Glyoxalase/bleomycin resistance protein/dioxygenase)|interpro:IPR029068|go:""GO:0003868""(4-hydroxyphenylpyruvate dioxygenase activity)|go:""GO:0006572""(tyrosine catabolic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000810913.1|interpro:IPR037523|interpro:IPR041735|interpro:IPR041736"	"efo:""Orphanet:52022""|dip:DIP-60252N|ensembl:ENSG00000135365.17(gene)|ensembl:ENST00000418153.6(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0046872""(metal ion binding)|go:""GO:1990391""(DNA repair complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q96BD5|rcsb pdb:2PUY|rcsb pdb:2YQL|reactome:R-HSA-3214815|reactome:R-HSA-9679191|reactome:R-HSA-983231|refseq:NP_001095272.1|refseq:NP_057705.3|refseq:XP_005253022.1|refseq:XP_011518475.1|refseq:XP_011518476.1|refseq:XP_011518481.1|refseq:XP_016873380.1|panther:PTHR24102(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/12	rogid:9GuCkBxrf6oRvFwDRigjGEIWyPs1392	rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606	intact-crc:769FACDD4E07DF03|rigid:xFCLfRsXULLNi9fAf4wLt2wLyO8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L8Q0F3	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2810486|uniprotkb:Q6HXP0|uniprotkb:Q6KRR4|uniprotkb:E9QW99|uniprotkb:E9QWA0|uniprotkb:A0A2P0HF19|uniprotkb:Q81PH5	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l8q0f3_bacan(display_long)|uniprotkb:GBAA_2830(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810491|imex:IM-13779-1450	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR001463(""Sodium:alanine symporter"")|go:""GO:0005283""(""amino acid:sodium symporter activity"")|go:""GO:0005886""(plasma membrane)|refseq:WP_000436991.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:Rglrw8eG7YXx10FTKrIu7U1sNCM1392	intact-crc:7DDFF927C8D552E5|rigid:npc9TwWMnJ37x2tdEJJ09tpm5Gg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P47974	uniprotkb:A0A6L8P0S7	intact:EBI-1644149|uniprotkb:Q9BSJ3|intact:EBI-2810458|uniprotkb:Q53TB4|ensembl:ENSP00000282388.3	intact:EBI-2810464|uniprotkb:Q6I496|uniprotkb:Q6KY01|uniprotkb:E9QVG1|uniprotkb:E9QVG2|uniprotkb:Q81ZF0|uniprotkb:A0A1J9VUR9	psi-mi:tisd_human(display_long)|uniprotkb:ZFP36L2(gene name)|psi-mi:ZFP36L2(display_short)|uniprotkb:ERF2(gene name synonym)|uniprotkb:RNF162C(gene name synonym)|uniprotkb:TIS11D(gene name synonym)|uniprotkb:EGF-response factor 2(gene name synonym)|uniprotkb:Butyrate response factor 2(gene name synonym)|uniprotkb:TPA-induced sequence 11d(gene name synonym)|uniprotkb:Zinc finger protein 36, C3H1 type-like 2(gene name synonym)	psi-mi:a0a6l8p0s7_bacan(display_long)|uniprotkb:GBAA_0318(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810455|imex:IM-13779-1449	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:675396""|ensembl:ENSG00000152518.8(gene)|ensembl:ENST00000282388.4(transcript)|go:""GO:0000288""(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0009611""(response to wounding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0048103""(somatic stem cell division)|go:""GO:0060216""(definitive hemopoiesis)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0097011""(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901991""(negative regulation of mitotic cell cycle phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000737""(negative regulation of stem cell differentiation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR007635(Tis11B like protein, N-terminal)|interpro:IPR036855|interpro:IPR045877|rcsb pdb:1RGO|reactome:R-HSA-9820841|refseq:NP_008818.3|efo:""Orphanet:400025""|panther:PTHR12547(orthology-group)"	"interpro:IPR000835(Bacterial regulatory protein, MarR)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|refseq:WP_000942488.1|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SrumP5lqWb6Q9N2deBcna8zmhCA9606	rogid:820v7tJWdYsnfGnEye9iwlXA+uI1392	intact-crc:D806669DB0199B4A|rigid:y62v09P8m0BaIuLGzT6fIQqJHYc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75376	uniprotkb:D1MPX1	intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|uniprotkb:B3DLF8|ensembl:ENSP00000268712.2	intact:EBI-63974340	psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym)	psi-mi:d1mpx1_bacan(display_long)|uniprotkb:GBAA_1376(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810498|imex:IM-13779-1448	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-29402N|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1|refseq:XP_011522388.1|panther:PTHR13992(orthology-group)|ensembl:ENSG00000141027.23(gene)|ensembl:ENST00000268712.8(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0016020""(membrane)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045820""(negative regulation of glycolytic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045922""(negative regulation of fatty acid metabolic process)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0072686""(mitotic spindle)|go:""GO:1902894""(negative regulation of miRNA transcription)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|interpro:IPR051571|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3H52|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6WMS|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|rcsb pdb:8AS9|rcsb pdb:8D8I|rcsb pdb:8DKN|rcsb pdb:8DKV|rcsb pdb:8FHE|rcsb pdb:8FHG|rcsb pdb:8FKC|rcsb pdb:8FKD|rcsb pdb:8FKE|rcsb pdb:8FKF|rcsb pdb:8FKG|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|ensembl:ENSP00000268712.2|ensembl:ENST00000395848.5|ensembl:ENSP00000379189.1|ensembl:ENST00000395851.5|ensembl:ENSP00000379192.1"	"go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR027417"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/21	rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606	rogid:jbnlz3pIyPJMnl4WcqVYdWRQ7u01392	intact-crc:27AC5637BA8AAE72|rigid:T0GcE9opxP3MKqVxTpt6M7F0hhw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2C3H3W1	uniprotkb:Q9Y6Q9	intact:EBI-2810510|uniprotkb:Q6KKB3|uniprotkb:Q6HQZ4|uniprotkb:A0A0J1HQ70|uniprotkb:E9R3S1|uniprotkb:E9R3S2|uniprotkb:Q81X58|uniprotkb:A0A2A8YC97	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066.3|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	psi-mi:a0a2c3h3w1_bacan(display_long)|uniprotkb:GBAA_5385(locus name)	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810515|imex:IM-13779-1451	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR020476|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:WP_001190080.1	"refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151.19(gene)|ensembl:ENST00000371998.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035624""(receptor transactivation)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043697""(cell dedifferentiation)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070561""(vitamin D receptor signaling pathway)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|dip:DIP-30876N|ensembl:ENST00000371997.3|ensembl:ENSP00000361065.3|ensembl:ENSP00000361066.3|ensembl:ENST00000372004.7|ensembl:ENSP00000361073.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/12	rogid:4tbkJWoA+dRxYkFmG6oQIUl7tto1392	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	intact-crc:60CA24FA840E7CD4|rigid:R8V6Z3jkf9BUHd+vFxgZLM7Ab2s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04233	uniprotkb:A0A6L8PTT5	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-2810562|uniprotkb:Q6HVR1|uniprotkb:Q6KPX8|uniprotkb:E9R792|uniprotkb:E9R793|uniprotkb:Q81YG8|uniprotkb:A0A0F7REJ1	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:a0a6l8ptt5_bacan(display_long)|uniprotkb:GBAA_3581(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810559|imex:IM-13779-1456	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"interpro:IPR000653(DegT/DnrJ/EryC1/StrS aminotransferase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:""GO:0000271""(polysaccharide biosynthetic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:WP_001084732.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:Q0pKzwIux3ytDFlAgGr8eyehbos1392	intact-crc:3D2838A52730A0A1|rigid:T7K+8JjRGzB0yqc/RX4R5pROYas	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P8C7	uniprotkb:P14618	intact:EBI-2810538|uniprotkb:Q6I431|uniprotkb:Q6KXU1|uniprotkb:E9QZZ6|uniprotkb:E9QZZ7|uniprotkb:Q81Z89|uniprotkb:A0A0F7RNP9	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	psi-mi:a0a6l8p8c7_bacan(display_long)|uniprotkb:GBAA_0383(locus name)	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810535|imex:IM-13779-1455	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR050166|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_001214740.1"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:diwLDAlsK64CnkmfZM0zpnyynl81392	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	intact-crc:4E4174B0F107B1E2|rigid:MDzk3ipMdbGX8d3VmT21/qAO61U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14154	uniprotkb:A0A6L8PBB8	intact:EBI-2805660|uniprotkb:Q969R4|uniprotkb:Q96EU9|intact:EBI-2831226|ensembl:ENSP00000194118.4|ensembl:ENSP00000396225.2	intact:EBI-2810547|uniprotkb:Q6KWH8|uniprotkb:Q6I2Q0|uniprotkb:E9QV37|uniprotkb:E9QV38|uniprotkb:Q81UH0|uniprotkb:A0A0F7RGK4	psi-mi:dele1_human(display_long)|uniprotkb:DELE1(gene name)|psi-mi:DELE1(display_short)|uniprotkb:DELE(gene name synonym)|uniprotkb:Death ligand signal enhancer(gene name synonym)|uniprotkb:KIAA0141(gene name synonym)|uniprotkb:DAP3-binding cell death enhancer 1, long form(gene name synonym)	psi-mi:a0a6l8pbb8_bacan(display_long)|uniprotkb:GBAA_0902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810552|imex:IM-13779-1453	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001136075.1|refseq:NP_055588.3|refseq:XP_005268604.1|refseq:XP_005268605.1|ensembl:ENSG00000081791.9(gene)|ensembl:ENST00000194118.8(transcript)|ensembl:ENST00000432126.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0033554""(cellular response to stress)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0140468""(HRI-mediated signaling)|go:""GO:1901526""(positive regulation of mitophagy)|go:""GO:1990641""(response to iron ion starvation)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR052748|rcsb pdb:8D9X|reactome:R-HSA-9840373|panther:PTHR45011(orthology-group)"	"interpro:IPR003462(Ornithine cyclodeaminase/mu-crystallin)|interpro:IPR023401|go:""GO:0005737""(cytoplasm)|refseq:WP_000960276.1|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UBQ+baEp+eubj9KvSTnUTdJLq9g9606	rogid:A71+jKUZLyfZWvjcF3aw6Zz7k5w1392	intact-crc:77659DBF8BBE049E|rigid:/U9PRK5upO3IT1nkNSWz9gmuPAM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q04900	uniprotkb:A0A6L7H169	intact:EBI-2115896|uniprotkb:Q5JSU6|uniprotkb:E1P5E8|uniprotkb:E1P5E7|uniprotkb:E1P5E9|uniprotkb:B4DQ85|uniprotkb:O95413|uniprotkb:Q9BPV0|uniprotkb:Q9NR26|ensembl:ENSP00000309376.4	intact:EBI-2810522|uniprotkb:Q6KN99|uniprotkb:Q6HU17|uniprotkb:E9QV88|uniprotkb:E9QV89|uniprotkb:Q81ML9|uniprotkb:A0A0F7RCP2	psi-mi:muc24_human(display_long)|uniprotkb:Endolyn(gene name synonym)|uniprotkb:CD164(gene name)|psi-mi:CD164(display_short)|uniprotkb:Multi-glycosylated core protein 24(gene name synonym)	psi-mi:a0a6l7h169_bacan(display_long)|uniprotkb:GBAA_4228(locus name)|uniprotkb:malC(gene name)|psi-mi:malC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810528|imex:IM-13779-1452	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11337(orthology-group)|efo:""Orphanet:90635""|dip:DIP-43970N|ensembl:ENSG00000135535.17(gene)|ensembl:ENST00000310786.10(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007517""(muscle organ development)|go:""GO:0010008""(endosome membrane)|go:""GO:0030097""(hemopoiesis)|interpro:IPR007947(CD164 related protein)|mint:Q04900|refseq:NP_001135873.1|refseq:NP_001135874.1|refseq:NP_001135875.1|refseq:NP_001135876.1|refseq:NP_001333429.1|refseq:NP_006007.2"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0015423""(ABC-type maltose transporter activity)|go:""GO:0042956""(maltodextrin transmembrane transport)|go:""GO:1990060""(maltose transport complex)|refseq:WP_001194985.1|interpro:IPR035906"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RnECOHDDKJ98oN/MPUzPHIwRePs9606	rogid:aPutFgOPyiin0JS5cILRMtq8Tjg1392	intact-crc:8B1B5CAFC4282E76|rigid:SRHakPP5ir1o7ZX/x7UwmtfWWdc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81R83	uniprotkb:Q14192	intact:EBI-2810574|uniprotkb:Q6KTE5|uniprotkb:Q6HZF6	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	psi-mi:y2173_bacan(display_long)|uniprotkb:BA_2173(locus name)|uniprotkb:GBAA_2173(locus name)|uniprotkb:BAS2019(locus name)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810571|imex:IM-13779-1454	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009474(Protein of unknown function DUF1094)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_000063712.1|refseq:NP_844566.1|refseq:YP_028282.1"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:DwG1RQbAdj088ZOY9O74UrEBXms1392	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:A9BCA720980F84DC|rigid:vfamGncaNnMi8fI2HiP6quiYRow	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HLW1	uniprotkb:P15822	intact:EBI-2810622|uniprotkb:Q6I1B2|uniprotkb:Q6KV59|uniprotkb:E9R3R3|uniprotkb:E9R3R4|uniprotkb:Q81T30|uniprotkb:A0A0F7RK40	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	psi-mi:a0a6l7hlw1_bacan(display_long)|uniprotkb:brnQ3(gene name)|psi-mi:brnQ3(display_short)|uniprotkb:GBAA_1459(locus name)	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810619|imex:IM-13779-1458	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004685(Branched-chain amino acid transport system II carrier protein)|go:""GO:0005304""(L-valine transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0015188""(L-isoleucine transmembrane transporter activity)|go:""GO:0015190""(L-leucine transmembrane transporter activity)|go:""GO:0015818""(isoleucine transport)|go:""GO:0015820""(L-leucine transport)|refseq:WP_001099157.1"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dtoOAUiZxe+vfVjtKonz3QioyXw1392	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	intact-crc:932CDEC0829A9E15|rigid:1gB/hDTJ2VtpEEHXEE3+oeCYuXs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PDF7	uniprotkb:Q99828	intact:EBI-2810594|uniprotkb:Q6KW06|uniprotkb:Q6I272|uniprotkb:E9QVC8|uniprotkb:E9QVC9|uniprotkb:Q81TY6|uniprotkb:A0A0F7RMC5	intact:EBI-372594|uniprotkb:B5BU40|uniprotkb:O00693|uniprotkb:O00735|uniprotkb:Q6IB49|uniprotkb:Q96J54|uniprotkb:Q99971|ensembl:ENSP00000333873.6|uniprotkb:H6WJF3	psi-mi:a0a6l8pdf7_bacan(display_long)|uniprotkb:GBAA_1114(locus name)	psi-mi:cib1_human(display_long)|uniprotkb:Calmyrin(gene name synonym)|uniprotkb:DNA-PKcs-interacting protein(gene name synonym)|uniprotkb:Kinase-interacting protein(gene name synonym)|uniprotkb:SNK-interacting protein 2-28(gene name synonym)|uniprotkb:CIB1(gene name)|psi-mi:CIB1(display_short)|uniprotkb:CIB(gene name synonym)|uniprotkb:KIP(gene name synonym)|uniprotkb:PRKDCIP(gene name synonym)|uniprotkb:Calcium- and integrin-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810599|imex:IM-13779-1457	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029441|interpro:IPR010499(Bacterial transcription activator, effector binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018062|interpro:IPR018060|interpro:IPR011256(Regulatory factor, effector, bacterial)|interpro:IPR020449|interpro:IPR053182|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0043565""(sequence-specific DNA binding)|refseq:WP_000446832.1"	"go:""GO:0006302""(double-strand break repair)|go:""GO:0006915""(apoptotic process)|panther:PTHR45791(orthology-group)|go:""GO:0006974""(DNA damage response)|ensembl:ENSG00000185043.13(gene)|ensembl:ENST00000328649.11(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0002931""(response to ischemia)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0007026""(negative regulation of microtubule depolymerization)|go:""GO:0007113""(endomitotic cell cycle)|go:""GO:0007155""(cell adhesion)|go:""GO:0007286""(spermatid development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008427""(calcium-dependent protein kinase inhibitor activity)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030220""(platelet formation)|go:""GO:0030291""(protein serine/threonine kinase inhibitor activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0030426""(growth cone)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031982""(vesicle)|go:""GO:0032433""(filopodium tip)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033630""(positive regulation of cell adhesion mediated by integrin)|go:""GO:0038163""(thrombopoietin-mediated signaling pathway)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043085""(positive regulation of catalytic activity)|go:""GO:0043204""(perikaryon)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045653""(negative regulation of megakaryocyte differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051301""(cell division)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070886""(positive regulation of calcineurin-NFAT signaling cascade)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0071944""(cell periphery)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:2000256""(positive regulation of male germ cell proliferation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR051433|mint:Q99828|rcsb pdb:1DGU|rcsb pdb:1DGV|rcsb pdb:1XO5|rcsb pdb:1Y1A|rcsb pdb:2L4H|rcsb pdb:2L4I|rcsb pdb:2LM5|rcsb pdb:6OCX|rcsb pdb:6OD0|refseq:NP_001264693.1|refseq:NP_006375.2|efo:""Orphanet:302""|dip:DIP-31260N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:JhKSQU+Dy6soIOR2a8KdT3BUrsA1392	rogid:6nPuuJSN/emL6jukTGtT2ab+jNU9606	intact-crc:12E6BD83D8601F95|rigid:lSm3KuUCMI2zSaXrycZfOmkgOik	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3P1U4C2	uniprotkb:Q9C005	intact:EBI-2810583|uniprotkb:Q6KQI2|uniprotkb:E9QS96|uniprotkb:Q81N73	intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066.3|ensembl:ENSP00000345837.5	psi-mi:a0a3p1u4c2_bacan(display_long)|uniprotkb:GBAA_3344(locus name)	psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810587|imex:IM-13779-1459	author score:7|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000835(Bacterial regulatory protein, MarR)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|refseq:WP_000343680.1|interpro:IPR036388|interpro:IPR036390"	"refseq:NP_115963.1|refseq:NP_001308138.1|dip:DIP-34476N|ensembl:ENSG00000162961.14(gene)|ensembl:ENST00000295066.3(transcript)|ensembl:ENST00000342166.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0016197""(endosomal transport)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0071339""(MLL1 complex)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|interpro:IPR049629|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|rcsb pdb:7UD5|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:F0CKXSC8hAIBFADH7ltdnoTnzWc1392	rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606	intact-crc:AC1425552B2286D1|rigid:BcaMNtMgFLzGcuzKMdoUiQ5eTk4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:Q9H4A3	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-457907|uniprotkb:O15052|uniprotkb:P54963|uniprotkb:Q86WL5|uniprotkb:Q8N673|uniprotkb:Q9P1S9|uniprotkb:Q4VBX9|intact:EBI-948424|uniprotkb:A1L4B0|uniprotkb:Q6IFS5|uniprotkb:C5HTZ5|uniprotkb:C5HTZ6|uniprotkb:C5HTZ7|uniprotkb:H6WZW3|uniprotkb:Q96CZ6|ensembl:ENSP00000313059.6	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:wnk1_human(display_long)|uniprotkb:WNK1(gene name)|psi-mi:WNK1(display_short)|uniprotkb:KDP(gene name synonym)|uniprotkb:KIAA0344(gene name synonym)|uniprotkb:PRKWNK1(gene name synonym)|uniprotkb:Protein kinase with no lysine 1(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 1(gene name synonym)|uniprotkb:Erythrocyte 65 kDa protein(gene name synonym)|uniprotkb:Kinase deficient protein(gene name synonym)|uniprotkb:HSN2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810632|imex:IM-13779-1461	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"efo:""Orphanet:88940""|efo:""Orphanet:970""|ensembl:ENSG00000060237.19(gene)|ensembl:ENST00000315939.11(transcript)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0007165""(signal transduction)|go:""GO:0007507""(heart development)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010766""(negative regulation of sodium ion transport)|go:""GO:0010793""(regulation of mRNA export from nucleus)|go:""GO:0010820""(positive regulation of T cell chemotaxis)|go:""GO:0016020""(membrane)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0030644""(intracellular chloride ion homeostasis)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033633""(negative regulation of cell-cell adhesion mediated by integrin)|go:""GO:0034115""(negative regulation of heterotypic cell-cell adhesion)|go:""GO:0034260""(negative regulation of GTPase activity)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038116""(""chemokine (C-C motif) ligand 21 signaling pathway"")|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048666""(neuron development)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0055075""(potassium ion homeostasis)|go:""GO:0055080""(monoatomic cation homeostasis)|go:""GO:0071474""(cellular hyperosmotic response)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090188""(negative regulation of pancreatic juice secretion)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097022""(lymphocyte migration into lymph node)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1902305""(regulation of sodium ion transmembrane transport)|go:""GO:1903038""(negative regulation of leukocyte cell-cell adhesion)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:1903490""(positive regulation of mitotic cytokinesis)|go:""GO:1904062""(regulation of monoatomic cation transmembrane transport)|go:""GO:1904595""(positive regulation of termination of RNA polymerase II transcription)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990869""(cellular response to chemokine)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|interpro:IPR050588|mint:Q9H4A3|rcsb pdb:4PWN|rcsb pdb:5TF9|rcsb pdb:5WDY|rcsb pdb:5WE8|rcsb pdb:6FBK|reactome:R-HSA-2672351|refseq:NP_001171914.1|refseq:NP_055638.2|refseq:NP_061852.3|refseq:NP_998820.3|refseq:XP_016875326.1|refseq:XP_016875327.1|dip:DIP-32648N|panther:PTHR24361(orthology-group)|ensembl:ENSP00000313059.6|ensembl:ENST00000340908.9|ensembl:ENSP00000341292.5|ensembl:ENST00000530271.6|ensembl:ENSP00000433548.3|ensembl:ENST00000537687.5|ensembl:ENSP00000444465.1|ensembl:ENST00000675631.1|ensembl:ENSP00000502415.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/06	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:Jt4cvhSumyRRIZDmWgj4GsG7wjQ9606	intact-crc:83C0FE432E692641|rigid:fGW2wpFsYA3xvutpgLAwenHpuFk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WE9	uniprotkb:P17028	intact:EBI-2810609|uniprotkb:Q6HUJ7|uniprotkb:Q6KNT2	intact:EBI-707773|uniprotkb:O14754|uniprotkb:Q53YE4|uniprotkb:Q6ICR5|uniprotkb:Q8IZN4|ensembl:ENSP00000261332.5|ensembl:ENSP00000382015.2	psi-mi:pyrb_bacan(display_long)|uniprotkb:pyrB(gene name)|psi-mi:pyrB(display_short)|uniprotkb:Aspartate transcarbamylase(gene name synonym)|uniprotkb:BA_4028(locus name)|uniprotkb:GBAA_4028(locus name)|uniprotkb:BAS3740(locus name)	psi-mi:znf24_human(display_long)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein KOX17(gene name synonym)|uniprotkb:Retinoic acid suppression protein A(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 3(gene name synonym)|uniprotkb:ZNF24(gene name)|psi-mi:ZNF24(display_short)|uniprotkb:KOX17(gene name synonym)|uniprotkb:ZNF191(gene name synonym)|uniprotkb:ZSCAN3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810606|imex:IM-13779-1460	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|go:""GO:0004070""(aspartate carbamoyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0016597""(amino acid binding)|go:""GO:0044205""('de novo' UMP biosynthetic process)|refseq:WP_000018849.1|interpro:IPR036901|refseq:NP_846269.1|refseq:YP_029991.1"	"refseq:NP_008896.2|refseq:XP_005258398.1|refseq:NP_001295052.1|ensembl:ENSG00000172466.16(gene)|ensembl:ENST00000261332.11(transcript)|ensembl:ENST00000399061.3(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0042552""(myelination)|go:""GO:0042802""(identical protein binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P17028|rcsb pdb:1X6E|rcsb pdb:3LHR|panther:PTHR23226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kYGPh/0/j5j2yg9ZpemwC1fkeWw1392	rogid:JkUMu2FtBQTBFKK1fj5wxMA1bjQ9606	intact-crc:78BE4C4E8E4C7E14|rigid:wxq8egLOlIGcKOg5/q4vUZkWhTM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15006	uniprotkb:Q81MN9	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853.3	intact:EBI-2810639|uniprotkb:Q6HU35|uniprotkb:Q6KNB9	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:ppk1_bacan(display_long)|uniprotkb:ppk(gene name)|psi-mi:ppk(display_short)|uniprotkb:ATP-polyphosphate phosphotransferase(gene name synonym)|uniprotkb:Polyphosphoric acid kinase(gene name synonym)|uniprotkb:BA_4208(locus name)|uniprotkb:GBAA_4208(locus name)|uniprotkb:BAS3903(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810645|imex:IM-13779-1462	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055488.1|ensembl:ENSG00000104412.8(gene)|ensembl:ENST00000220853.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0042406""(extrinsic component of endoplasmic reticulum membrane)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072546""(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|interpro:IPR055217|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|rcsb pdb:8EOI|rcsb pdb:8J0N|rcsb pdb:8J0O|rcsb pdb:8S9S|rcsb pdb:9C7V|panther:PTHR12760(orthology-group)"	"interpro:IPR003414(Polyphosphate kinase)|interpro:IPR025198|interpro:IPR025200|interpro:IPR024953|go:""GO:0005524""(ATP binding)|go:""GO:0006799""(polyphosphate biosynthetic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0009358""(polyphosphate kinase complex)|go:""GO:0046872""(metal ion binding)|refseq:WP_000423561.1|interpro:IPR036830|interpro:IPR036832|interpro:IPR041108|refseq:NP_846443.1|refseq:YP_030153.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:XAQtpZmDcBUTqfHyM89FQx4seQo1392	intact-crc:78946206D75BBADE|rigid:5nKAgDVnGqJxWpwFK2Fg0v8nNRk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H421	uniprotkb:Q8NDV7	intact:EBI-2810652|uniprotkb:Q6KSG7|uniprotkb:Q6HYF9|uniprotkb:E9R9F4|uniprotkb:E9R9F5|uniprotkb:Q81Q87|uniprotkb:A0A0F7RDV9	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	psi-mi:a0a6l7h421_bacan(display_long)|uniprotkb:GBAA_2546(locus name)	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810657|imex:IM-13779-1464	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR013560(Protein of unknown function DUF1722)|interpro:IPR007553(Protein of unknown function DUF523)|interpro:IPR017087(Uncharacterised conserved protein UCP037004)|refseq:WP_001248630.1	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:2helogO2D/G85c/K2apFD3gNVOc1392	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	intact-crc:3D5D76FE6D0901A3|rigid:zbjGQPDtTfIldCj9Ch3EXlz5IFQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HME0	uniprotkb:Q9BYB0	intact:EBI-2810667|uniprotkb:A0A1Q4M2E8|uniprotkb:Q6I2C8|uniprotkb:Q6KW55|uniprotkb:E9R5K0|uniprotkb:E9R5K1|uniprotkb:Q81U40|uniprotkb:A0A1J9WHI8	intact:EBI-1752330|uniprotkb:D7UT47|uniprotkb:Q8TET3|intact:EBI-28969573	psi-mi:a0a6l7hme0_bacan(display_long)|uniprotkb:ecsA(gene name)|psi-mi:ecsA(display_short)|uniprotkb:GBAA_1048(locus name)	psi-mi:shan3_human(display_long)|uniprotkb:SHANK3(gene name)|psi-mi:SHANK3(display_short)|uniprotkb:KIAA1650(gene name synonym)|uniprotkb:PSAP2(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:PROSAP2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810664|imex:IM-13779-1463	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR051782|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_001292599.1"	"dip:DIP-52267N|efo:""Orphanet:662169""|efo:""Orphanet:662172""|go:""GO:0000165""(MAPK cascade)|go:""GO:0003779""(actin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007416""(synapse assembly)|go:""GO:0007612""(learning)|go:""GO:0007613""(memory)|go:""GO:0008270""(zinc ion binding)|go:""GO:0014069""(postsynaptic density)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0021773""(striatal medium spiny neuron differentiation)|go:""GO:0030160""(synaptic receptor adaptor activity)|go:""GO:0030534""(adult behavior)|go:""GO:0032232""(negative regulation of actin filament bundle assembly)|go:""GO:0035176""(social behavior)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0042297""(vocal learning)|go:""GO:0043005""(neuron projection)|go:""GO:0043197""(dendritic spine)|go:""GO:0044309""(neuron spine)|go:""GO:0045794""(negative regulation of cell volume)|go:""GO:0048170""(positive regulation of long-term neuronal synaptic plasticity)|go:""GO:0048854""(brain morphogenesis)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051968""(positive regulation of synaptic transmission, glutamatergic)|go:""GO:0060170""(ciliary membrane)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0060999""(positive regulation of dendritic spine development)|go:""GO:0061001""(regulation of dendritic spine morphogenesis)|go:""GO:0071625""(vocalization behavior)|go:""GO:0097107""(postsynaptic density assembly)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097113""(AMPA glutamate receptor clustering)|go:""GO:0097114""(NMDA glutamate receptor clustering)|go:""GO:0097117""(guanylate kinase-associated protein clustering)|go:""GO:1900271""(regulation of long-term synaptic potentiation)|go:""GO:1900273""(positive regulation of long-term synaptic potentiation)|go:""GO:1900451""(positive regulation of glutamate receptor signaling pathway)|go:""GO:1900452""(regulation of long-term synaptic depression)|go:""GO:2000463""(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|interpro:IPR051569|mint:Q9BYB0|rcsb pdb:6CPK|rcsb pdb:7C7I|rcsb pdb:7C7J|reactome:R-HSA-6794361|reactome:R-HSA-8853659|refseq:NP_277052.1|panther:PTHR24135(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlYld1pe8amcr3avJfCXz721u0I1392	rogid:lYflQon8u7cSZVzSr6IYNiWLZUY9606	intact-crc:4B9E5C4CAF135871|rigid:l8vpMHloDt1zyRxhdvTeE5nuk4c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3Q0PRJ6	uniprotkb:O00560	intact:EBI-2810680|uniprotkb:Q6KR31|uniprotkb:Q6HWZ9|uniprotkb:E9R4P7|uniprotkb:E9R4P8|uniprotkb:Q81NS9|uniprotkb:A0A0F7RCF4	intact:EBI-727004|uniprotkb:O43391|uniprotkb:O00173|uniprotkb:Q14CP2|ensembl:ENSP00000260130.4|ensembl:ENSP00000411771.2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:a0a3q0prj6_bacan(display_long)|uniprotkb:GBAA_3096(locus name)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810677|imex:IM-13779-1465	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003778(Allophanate hydrolase subunit 2)|interpro:IPR052708|interpro:IPR029000|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)"	"ensembl:ENSG00000137575.12(gene)|ensembl:ENST00000260130.9(transcript)|ensembl:ENST00000413219.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0005109""(frizzled binding)|go:""GO:0005137""(interleukin-5 receptor binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005895""(interleukin-5 receptor complex)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016020""(membrane)|go:""GO:0019838""(growth factor binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042043""(neurexin family protein binding)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045545""(syndecan binding)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0098793""(presynapse)|go:""GO:0099054""(presynapse assembly)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051230|mint:O00560|rcsb pdb:1N99|rcsb pdb:1NTE|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|rcsb pdb:7FSG|rcsb pdb:7FSH|rcsb pdb:7FSI|rcsb pdb:7FSJ|rcsb pdb:7FSK|rcsb pdb:7FSL|rcsb pdb:7FT5|rcsb pdb:7FSM|rcsb pdb:7FSN|rcsb pdb:7FSO|rcsb pdb:7FSP|rcsb pdb:7FSQ|rcsb pdb:7FSR|rcsb pdb:7FSS|rcsb pdb:7FST|rcsb pdb:7FSU|rcsb pdb:7FSV|rcsb pdb:7FSW|rcsb pdb:7FSX|rcsb pdb:7FSY|rcsb pdb:7FSZ|rcsb pdb:7FT0|rcsb pdb:7FT1|rcsb pdb:7FT2|rcsb pdb:7FT3|rcsb pdb:7FT4|rcsb pdb:7FT6|rcsb pdb:7FT7|rcsb pdb:7FT8|rcsb pdb:7FT9|rcsb pdb:7FTA|rcsb pdb:7FTB|rcsb pdb:7FTC|rcsb pdb:7FTD|rcsb pdb:8AAI|rcsb pdb:8AAK|rcsb pdb:8AAO|rcsb pdb:8AAP|rcsb pdb:8BLU|rcsb pdb:8BLV|rcsb pdb:8HCK|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-6798695|refseq:NP_001007068.1|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|dip:DIP-42705N|panther:PTHR12345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:NUa3lWGCm+fzNXodfOc6AoaBPi01392	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	intact-crc:E0EFA4B6BCCB92D4|rigid:2PVv4naP9r9w6xI/Yizh1iWeGEc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HH45	uniprotkb:Q7Z3K3	intact:EBI-2810739|uniprotkb:Q6KQJ9|uniprotkb:Q6HWF0|uniprotkb:E9R0C6|uniprotkb:E9R0C7|uniprotkb:Q81N92|uniprotkb:A0A0F7RF31	intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-11742841|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715.2|ensembl:ENSP00000390156.2	psi-mi:a0a6l7hh45_bacan(display_long)|uniprotkb:GBAA_3323(locus name)	psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810744|imex:IM-13779-1468	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025672|interpro:IPR029101|go:""GO:0016020""(membrane)|refseq:WP_000180324.1"	"dip:DIP-38044N|ensembl:ENSG00000143442.24(gene)|ensembl:ENST00000271715.7(transcript)|ensembl:ENST00000439756.2(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0051382""(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050527|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|panther:PTHR24403(orthology-group)|efo:""Orphanet:468678"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WHI2kqITIISGoQqFf8Ewpzg/Ms01392	rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606	intact-crc:8C63CBD4D007C400|rigid:uH5n6PI3YQIJawSFISfjpWQ0jvM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81L10	uniprotkb:Q4VAK3	intact:EBI-2810713|uniprotkb:Q6KLR0|uniprotkb:Q6HSG5	intact:EBI-2803046	psi-mi:nrdr_bacan(display_long)|uniprotkb:nrdR(gene name)|psi-mi:nrdR(display_short)|uniprotkb:BA_4824(locus name)|uniprotkb:GBAA_4824(locus name)|uniprotkb:BAS4476(locus name)	psi-mi:q4vak3_human(display_long)|uniprotkb:OFD1(gene name)|psi-mi:OFD1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810719|imex:IM-13779-1467	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005144(ATP-cone)|interpro:IPR003796(Ribonucleotide reductase regulator NrdR-like)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR055173|refseq:WP_001203687.1|refseq:NP_847027.2|refseq:YP_030723.1"	interpro:IPR055289	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kG3YzLvKveoCeDX0WPFsMLvS+a01392	rogid:89UeJ/4mu1bIHqVh+2BOq1G1SoM9606	intact-crc:1FEF081EE0AFC7B4|rigid:jKUnNhH86LuZfGjWN87zzGKHwLU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PBR9	uniprotkb:Q9C099	intact:EBI-2810701|uniprotkb:Q6I1Q5|uniprotkb:Q6KVJ7|uniprotkb:E9QV27|uniprotkb:E9QV28|uniprotkb:Q81TH2|uniprotkb:A0A1J9UYI5	intact:EBI-725598|intact:EBI-2802231|uniprotkb:Q8N768|uniprotkb:Q96DK7|uniprotkb:Q96N01|uniprotkb:B4DYX6|uniprotkb:B5RI11|ensembl:ENSP00000353538.3	psi-mi:a0a6l8pbr9_bacan(display_long)|uniprotkb:GBAA_1303(locus name)	psi-mi:lrcc1_human(display_long)|uniprotkb:KIAA1764(gene name synonym)|uniprotkb:LRRCC1(gene name)|psi-mi:LRRCC1(display_short)|uniprotkb:CLERC(gene name synonym)|uniprotkb:Centrosomal leucine-rich repeat and coiled-coil domain-containing protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810706|imex:IM-13779-1470	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000490297.1	"refseq:NP_208325.3|ensembl:ENSG00000133739.16(gene)|ensembl:ENST00000360375.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0051301""(cell division)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|mint:Q9C099|panther:PTHR15454(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:18Maob9Whgm58MiBzcrlsOjPPVQ1392	rogid:uYbYWJqdbQuxk9vvo4N5JVaW8jU9606	intact-crc:DCE8B141403886BA|rigid:qQQVxtJDz6B8/PZ896jHBIlwHqo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WC4	uniprotkb:P62195	intact:EBI-2810729|uniprotkb:Q6HUG9|uniprotkb:Q6KNQ5|uniprotkb:E9R322|uniprotkb:E9R323	intact:EBI-357745|ensembl:ENSP00000310572.6|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3	psi-mi:ftsl_bacan(display_long)|uniprotkb:ftsL(gene name)|psi-mi:ftsL(display_short)|uniprotkb:GBAA_4056(locus name)|uniprotkb:BAS3768(locus name)|uniprotkb:BA_4056(locus name)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810726|imex:IM-13779-1469	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011922(Cell division protein, FtsL -like)|interpro:IPR007060(Septum formation initiator)|go:""GO:0005886""(plasma membrane)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|refseq:WP_000067081.1|refseq:NP_846296.1|refseq:YP_030019.1"	"ensembl:ENSG00000087191.14(gene)|ensembl:ENST00000310144.11(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008134""(transcription factor binding)|go:""GO:0008540""(proteasome regulatory particle, base subcomplex)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022624""(proteasome accessory complex)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031531""(thyrotropin-releasing hormone receptor binding)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1901800""(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|interpro:IPR050221|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:7QXN|rcsb pdb:7QXP|rcsb pdb:7QXU|rcsb pdb:7QXW|rcsb pdb:7QXX|rcsb pdb:7QY7|rcsb pdb:7QYA|rcsb pdb:7QYB|rcsb pdb:7W37|rcsb pdb:7W38|rcsb pdb:7W39|rcsb pdb:7W3A|rcsb pdb:7W3B|rcsb pdb:7W3C|rcsb pdb:7W3F|rcsb pdb:7W3G|rcsb pdb:7W3H|rcsb pdb:7W3I|rcsb pdb:7W3J|rcsb pdb:7W3K|rcsb pdb:7W3M|rcsb pdb:8CVT|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9755511|reactome:R-HSA-9762114|reactome:R-HSA-9824272|reactome:R-HSA-983168|reactome:R-HSA-9907900|panther:PTHR23073(orthology-group)|refseq:NP_001186092.1|refseq:NP_002796.4|dip:DIP-36645N"	"psi-mi:""MI:0469""(intact)"	-	crc64:29C6410C4A85A7F7	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:q5Syhc79fVumkDE4PezixCDRSyM1392	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	intact-crc:A15D63F13B2B0390|rigid:qI+yXzoWHTyxVdUo4DjGdnDnXJw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PD01	uniprotkb:Q9UQC1	intact:EBI-2810689|uniprotkb:Q6KR00|uniprotkb:Q6HWW8|uniprotkb:E9QQS7|uniprotkb:E9QQS8|uniprotkb:Q81NP8	intact:EBI-354981	psi-mi:a0a6l8pd01_bacan(display_long)|uniprotkb:GBAA_3131(locus name)	psi-mi:q9uqc1_human(display_long)|uniprotkb:HSP70-1(gene name)|psi-mi:HSP70-1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810694|imex:IM-13779-1466	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR036291|refseq:WP_000649082.1"	"interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR043129"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zX4+aIdzhDeWoVC9l0OlbVnHVow1392	rogid:5CycxNHAEy8lDjRntw5Gv8eHQGE9606	intact-crc:2146F5FD715D6D11|rigid:ydjsOrnf5fWrBsgi5TsbV/V7Qh0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L8PCV1	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2810776|uniprotkb:Q6F0C9|uniprotkb:E9RCD5|uniprotkb:Q81YV1	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l8pcv1_bacan(display_long)|uniprotkb:GBAA_0530(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810781|imex:IM-13779-1474	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017932|interpro:IPR002489(Glutamate synthase, alpha subunit, C-terminal)|interpro:IPR002932(Glutamate synthase, central-C)|interpro:IPR006982(Glutamate synthase, central-N)|interpro:IPR050711|interpro:IPR029055|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0015930""(glutamate synthase activity)|go:""GO:0019676""(ammonia assimilation cycle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051538""(3 iron, 4 sulfur cluster binding)|refseq:WP_000932985.1|interpro:IPR036485"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:Z+uk/bQaNmBqmHvxKudlUwj/uWE1392	intact-crc:2079A6A93897FDC6|rigid:CONEcu53HQ7GYQLemiXcL10lDk4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q81MB6	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2810766|uniprotkb:Q6HTR8|uniprotkb:Q6KN06	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:ribba_bacan(display_long)|uniprotkb:ribBA(gene name)|psi-mi:ribBA(display_short)|uniprotkb:BA_4333(locus name)|uniprotkb:GBAA_4333(locus name)|uniprotkb:BAS4020(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810763|imex:IM-13779-1471	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR017945|interpro:IPR000422(3,4-Dihydroxy-2-butanone 4-phosphate synthase)|interpro:IPR000926(GTP cyclohydrolase II)|interpro:IPR016299(Riboflavin biosynthesis protein RibA)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003935""(GTP cyclohydrolase II activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008686""(3,4-dihydroxy-2-butanone-4-phosphate synthase activity)|go:""GO:0009231""(riboflavin biosynthetic process)|go:""GO:0030145""(manganese ion binding)|refseq:WP_000469013.1|interpro:IPR032677|interpro:IPR036144|refseq:NP_846566.1|refseq:YP_030270.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:OX+juO2iF8QZRAF49UGw/v+kdN81392	intact-crc:AEDC020079CF8F09|rigid:TMheXYsEtDMQ/4Am+xsqckez5aM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HBC4	uniprotkb:O75592	intact:EBI-2810788|uniprotkb:Q6KXL0|uniprotkb:Q6I3U6|uniprotkb:E9QRV8|uniprotkb:E9QRV9|uniprotkb:Q81Z00|uniprotkb:A0A0F7RHU0	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596.2	psi-mi:a0a6l7hbc4_bacan(display_long)|uniprotkb:GBAA_0477(locus name)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810794|imex:IM-13779-1472	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_000233050.1"	"refseq:NP_055872.4|dip:DIP-28142N|ensembl:ENSG00000005810.20(gene)|ensembl:ENST00000544440.7(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030424""(axon)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902667""(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|panther:PTHR45943(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:GD/eq1rFPJzytQeLBsTJuqb9MWc1392	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:589548393F05EFC6|rigid:9EQvSGSQIHfFM46taXRENWzoxws	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13438	uniprotkb:A0A2B6C3E8	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|uniprotkb:E7EW91|uniprotkb:G3XA88|ensembl:ENSP00000318165.7	intact:EBI-2810754|uniprotkb:Q6KN14|uniprotkb:Q6HTS7|uniprotkb:E9QX86|uniprotkb:E9QX87|uniprotkb:Q81MC5|uniprotkb:A0A1Q4M6S3	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:a0a2b6c3e8_bacan(display_long)|uniprotkb:Prolyl aminopeptidase(gene name synonym)|uniprotkb:GBAA_4324(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810751|imex:IM-13779-1473	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|dip:DIP-37493N|ensembl:ENSG00000135506.17(gene)|ensembl:ENST00000315970.12(transcript)|go:""GO:0000836""(Hrd1p ubiquitin ligase complex)|go:""GO:0002020""(protease binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006605""(protein targeting)|go:""GO:0006621""(protein retention in ER lumen)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:1904153""(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|interpro:IPR045149|mint:Q13438|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|panther:PTHR15414(orthology-group)"	"interpro:IPR002410(Peptidase S33, prolyl aminopeptidase)|interpro:IPR029058|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006508""(proteolysis)|interpro:IPR005944(Peptidase S33, proline iminopeptidase 1)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|refseq:WP_000898981.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:HXCi382IX2ok1ZBXf1SSzyjVorI1392	intact-crc:3E506281C2C15D89|rigid:HgFUSjX7MXJQ6YZjV1jRRiJXAMY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HKK4	uniprotkb:P46379	intact:EBI-2810832|uniprotkb:Q6KUC2|uniprotkb:Q6I0F5|uniprotkb:E9R343|uniprotkb:E9R344|uniprotkb:Q81S73|uniprotkb:A0A1V4B4K7	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:a0a6l7hkk4_bacan(display_long)|uniprotkb:pyrH1(gene name)|psi-mi:pyrH1(display_short)|uniprotkb:Uridine monophosphate kinase(gene name synonym)|uniprotkb:pyrH(gene name synonym)|uniprotkb:GBAA_1797(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810838|imex:IM-13779-1476	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR011817(Uridylate kinase)|interpro:IPR015963(Uridylate kinase, bacteria)|rcsb pdb:2JJX|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006225""(UDP biosynthetic process)|go:""GO:0033862""(UMP kinase activity)|go:""GO:0044210""('de novo' CTP biosynthetic process)|refseq:WP_001248056.1|interpro:IPR036393"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dhD/kOG1Coln/84/inYwx4F9nSs1392	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:F7340B5D1553B9D7|rigid:9thpnOV3d8lX7qY+tk7AfzlYTfU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14618	uniprotkb:A0A6L8PZH2	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	intact:EBI-2810813|uniprotkb:Q6KQ97|uniprotkb:Q6HW41|uniprotkb:E9R080|uniprotkb:E9R081|uniprotkb:Q81MX7	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	psi-mi:a0a6l8pzh2_bacan(display_long)|uniprotkb:GBAA_3443(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810818|imex:IM-13779-1475	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	interpro:IPR004954(Peptidase M60, viral enhancin protein)|interpro:IPR031161|refseq:WP_000826235.1|interpro:IPR042279	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rogid:4lvwahEID9UJuvLFGgVnlmJW6KA1392	intact-crc:F43E940A002C6A66|rigid:OUBNiCBvMIcNpNrmofAaOTxt3WU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81TT4	uniprotkb:Q9UBW5	intact:EBI-2810319|uniprotkb:Q6KVV5|uniprotkb:Q6I218	intact:EBI-2042570|uniprotkb:Q86VV0|uniprotkb:Q9NWK4|uniprotkb:Q9UKN4|uniprotkb:B7Z6F3|uniprotkb:F5H0W4|ensembl:ENSP00000483983.2	psi-mi:clpb_bacan(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:BA_1177(locus name)|uniprotkb:GBAA_1177(locus name)|uniprotkb:BAS1090(locus name)	psi-mi:bin2_human(display_long)|uniprotkb:BIN2(gene name)|psi-mi:BIN2(display_short)|uniprotkb:BRAP1(gene name synonym)|uniprotkb:Breast cancer-associated protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810825|imex:IM-13779-1478	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR050130|interpro:IPR027417|interpro:IPR028299|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034605""(cellular response to heat)|go:""GO:0042026""(protein refolding)|refseq:WP_000365381.1|interpro:IPR036628|interpro:IPR041546|refseq:NP_843655.1|refseq:YP_027362.1"	"refseq:NP_001276936.1|refseq:NP_001276937.1|refseq:NP_001276938.1|refseq:NP_057377.3|panther:PTHR46514(orthology-group)|ensembl:ENSG00000110934.13(gene)|ensembl:ENST00000615107.6(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002102""(podosome)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042995""(cell projection)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070161""(anchoring junction)|go:""GO:0071800""(podosome assembly)|go:""GO:0097320""(plasma membrane tubulation)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003005(Amphiphysin)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR046984|interpro:IPR048886|rcsb pdb:4AVM|rcsb pdb:4I1Q|reactome:R-HSA-6798695|reactome:R-HSA-9673768"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RwqOsWdy9S7sYBI7SYTY7Mv0pSE1392	rogid:wD8yD0/ulLv6pt3ICEGRI+G0W0Y9606	intact-crc:824C1AEA75F261D0|rigid:Y85ATnZ0tIYADj2+5dyDvFmlxvo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94973	uniprotkb:Q81R83	intact:EBI-1642835|uniprotkb:O75403|uniprotkb:Q96SI8|uniprotkb:Q53ET1|ensembl:ENSP00000413234.3	intact:EBI-2810574|uniprotkb:Q6KTE5|uniprotkb:Q6HZF6	psi-mi:ap2a2_human(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:y2173_bacan(display_long)|uniprotkb:BA_2173(locus name)|uniprotkb:GBAA_2173(locus name)|uniprotkb:BAS2019(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810845|imex:IM-13779-1479	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229766.1|refseq:NP_036437.1|ensembl:ENSG00000183020.15(gene)|ensembl:ENST00000448903.7(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008289""(lipid binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR050840|mint:O94973|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-6798695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|panther:PTHR22780(orthology-group)"	"interpro:IPR009474(Protein of unknown function DUF1094)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_000063712.1|refseq:NP_844566.1|refseq:YP_028282.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sda1msOBssgmBiU3ZfSyk3z7/jc9606	rogid:DwG1RQbAdj088ZOY9O74UrEBXms1392	intact-crc:C43C763A715F4C54|rigid:GfREj4DeD9LKfo4mR9eQ6JH4PwE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16584	uniprotkb:A0A6L8PC29	intact:EBI-49961|uniprotkb:Q53H00|uniprotkb:Q59F06|uniprotkb:Q6P2G4|uniprotkb:B4DS76|ensembl:ENSP00000309597.3	intact:EBI-2810801|uniprotkb:Q6KRM4|uniprotkb:Q6HXJ8|uniprotkb:E9QRE3|uniprotkb:E9QRE4|uniprotkb:A0A2P0HF49|uniprotkb:Q81PD4	psi-mi:m3k11_human(display_long)|uniprotkb:MAP3K11(gene name)|psi-mi:MAP3K11(display_short)|uniprotkb:Mixed lineage kinase 3(gene name synonym)|uniprotkb:Src-homology 3 domain-containing proline-rich kinase(gene name synonym)|uniprotkb:SPRK(gene name synonym)|uniprotkb:PTK1(gene name synonym)|uniprotkb:MLK3(gene name synonym)	psi-mi:a0a6l8pc29_bacan(display_long)|uniprotkb:GBAA_2876(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810806|imex:IM-13779-1477	author score:6|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002410.1|panther:PTHR44329(orthology-group)|ensembl:ENSG00000173327.8(gene)|ensembl:ENST00000309100.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007017""(microtubule-based process)|go:""GO:0007254""(JNK cascade)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031434""(mitogen-activated protein kinase kinase binding)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044843""(cell cycle G1/S phase transition)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0106310""(protein serine kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016231(Mitogen-activated protein kinase kinase kinase, 9/10/11)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035779|interpro:IPR036028|interpro:IPR051681|mint:Q16584|rcsb pdb:5K26|rcsb pdb:5K28|rcsb pdb:6AQB|rcsb pdb:6CQ7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-9013148|reactome:R-HSA-9013408|reactome:R-HSA-9013424|reactome:R-HSA-9649948"	refseq:WP_001062740.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/06	rogid:njuMQIbuVFlWXNggegg3zYAKmS49606	rogid:4BbTj8554Gwm4rVypGL1Pva9DGE1392	intact-crc:45FB87B8A64A512C|rigid:TG+UVMGJ0o4QVtrOZwWbb7r9LlQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94842	uniprotkb:A0A6L7H5N1	intact:EBI-948613|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0|ensembl:ENSP00000393080.3|ensembl:ENSP00000477868.1	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810872|imex:IM-13779-1481	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055643.1|refseq:NP_001290452.1|ensembl:ENSG00000092203.15(gene)|ensembl:ENST00000448790.7(transcript)|ensembl:ENST00000613569.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR051365|mint:O94842|panther:PTHR45781(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:3318C717FAAD21FB|rigid:gcQ8SABS4HV8S1EteEQuPsqlbgQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04275	uniprotkb:Q81TL8	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	intact:EBI-2810855|uniprotkb:Q6KVP0|uniprotkb:Q6I1U8	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:trpb_bacan(display_long)|uniprotkb:trpB(gene name)|psi-mi:trpB(display_short)|uniprotkb:BA_1253(locus name)|uniprotkb:GBAA_1253(locus name)|uniprotkb:BAS1161(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810852|imex:IM-13779-1480	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"rcsb pdb:4NEG|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR006653(Tryptophan synthase, beta chain, conserved site)|interpro:IPR006654(Tryptophan synthase, beta chain)|interpro:IPR023026|go:""GO:0004834""(tryptophan synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006568""(L-tryptophan metabolic process)|refseq:WP_001105001.1|interpro:IPR036052|refseq:NP_843725.1|refseq:YP_027432.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:8bGGwe6QiCJpPhUQlmDzddcdDJc1392	intact-crc:F2654494D044703E|rigid:NQ/ZmiZDzHe8aJ2AzAFGaS9JLTk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96PV0	uniprotkb:A0A6L8PCK7	intact:EBI-2682386|uniprotkb:Q9UGE2|uniprotkb:A8MQC4|uniprotkb:Q8TCS2|uniprotkb:A2AB17|uniprotkb:A2BEL6|uniprotkb:A2BEL7|intact:EBI-28975552|ensembl:ENSP00000414259.2|ensembl:ENSP00000486463.1|ensembl:ENSP00000496007.1	intact:EBI-2810879|uniprotkb:Q6KQA6|uniprotkb:Q6HW50|uniprotkb:E9QU09|uniprotkb:E9QU10|uniprotkb:A0A2P0HGJ3|uniprotkb:Q81MY7	psi-mi:sygp1_human(display_long)|uniprotkb:KIAA1938(gene name synonym)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)|uniprotkb:SYNGAP1(gene name)|psi-mi:SYNGAP1(display_short)	psi-mi:a0a6l8pck7_bacan(display_long)|uniprotkb:GBAA_3432(locus name)|uniprotkb:tkt1(gene name)|psi-mi:tkt1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810885|imex:IM-13779-1484	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1942""|efo:""Orphanet:442835""|efo:""Orphanet:544254""|ensembl:ENSG00000197283.18(gene)|ensembl:ENSG00000227460.8(gene)|ensembl:ENST00000455687.6(transcript)|ensembl:ENST00000629380.3(transcript)|ensembl:ENST00000646630.1(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007389""(pattern specification process)|go:""GO:0007409""(axonogenesis)|go:""GO:0008542""(visual learning)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016358""(dendrite development)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0043113""(receptor clustering)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0046580""(negative regulation of Ras protein signal transduction)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0050771""(negative regulation of axonogenesis)|go:""GO:0050803""(regulation of synapse structure or activity)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0098880""(maintenance of postsynaptic specialization structure)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:Q96PV0|reactome:R-HSA-5658442|refseq:NP_001123538.1|refseq:NP_006763.2|panther:PTHR10194(orthology-group)"	"interpro:IPR033247|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR029061|go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|refseq:WP_000193036.1|interpro:IPR049557"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3Uq2PiuV/QQyjjPbPJS+CgN8+W89606	rogid:CAmYX1bWNU1J1p+yojcrnbiE0Ww1392	intact-crc:21907CF7EDB05D6E|rigid:SPSrXCJ0mmfPgNrAAFwo1UlnF4Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13423	uniprotkb:Q4FZB7	intact:EBI-456868|uniprotkb:Q937W2|uniprotkb:Q937W3|uniprotkb:Q9F5R7|uniprotkb:Q9KH69|uniprotkb:Q9RQU2	intact:EBI-1047962|uniprotkb:Q3SX56|uniprotkb:Q4V775|uniprotkb:Q6P150|uniprotkb:Q96E44|uniprotkb:Q9BUL0|uniprotkb:Q9H022|uniprotkb:Q9H2K3|uniprotkb:Q9NXV3|uniprotkb:Q9Y393|uniprotkb:B7WNX7|ensembl:ENSP00000305899.4|ensembl:ENSP00000484858.1|uniprotkb:A0A0A0MT19	psi-mi:pag_bacan(display_long)|uniprotkb:PA-83(gene name synonym)|uniprotkb:Anthrax toxins translocating protein(gene name synonym)|uniprotkb:pagA(gene name)|psi-mi:pagA(display_short)|uniprotkb:pag(gene name synonym)|uniprotkb:pXO1-110(locus name)|uniprotkb:BXA0164(locus name)|uniprotkb:GBAA_pXO1_0164(locus name)	psi-mi:kmt5b_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:CGI-85(orf name)|uniprotkb:KMT5B(gene name)|psi-mi:KMT5B(display_short)|uniprotkb:Lysine N-methyltransferase 5B(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5B(gene name synonym)|uniprotkb:SUV420H1(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810892|imex:IM-13779-1482	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P13423|refseq:NP_052806.1|refseq:WP_000746487.1|refseq:WP_000746486.1|refseq:WP_000746488.1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0044533""(obsolete positive regulation of apoptotic process in another organism)|go:""GO:0046872""(metal ion binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0090729""(toxin activity)|interpro:IPR003896(Bacterial exotoxin B)|interpro:IPR011658(PA14)|interpro:IPR027439|interpro:IPR027441|interpro:IPR035088|interpro:IPR035331|interpro:IPR037149|interpro:IPR037524|interpro:IPR048853|rcsb pdb:1ACC|rcsb pdb:1T6B|rcsb pdb:1TZN|rcsb pdb:1TZO|rcsb pdb:3ETB|rcsb pdb:3INO|rcsb pdb:3J9C|rcsb pdb:3KWV|rcsb pdb:3MHZ|rcsb pdb:3Q8A|rcsb pdb:3Q8B|rcsb pdb:3Q8C|rcsb pdb:3Q8E|rcsb pdb:3Q8F|rcsb pdb:3TEW|rcsb pdb:3TEX|rcsb pdb:3TEY|rcsb pdb:3TEZ|rcsb pdb:4EE2|rcsb pdb:4H2A|rcsb pdb:4NAM|rcsb pdb:5FR3|rcsb pdb:6PSN|rcsb pdb:6UJI|rcsb pdb:6UZB|rcsb pdb:6UZD|rcsb pdb:6UZE|rcsb pdb:6VRA|rcsb pdb:6WJJ|rcsb pdb:6ZXJ|rcsb pdb:6ZXK|rcsb pdb:6ZXL|rcsb pdb:7KXR|rcsb pdb:7O85|reactome:R-HSA-5210891|dip:DIP-29841N"	"efo:""Orphanet:684226""|ensembl:ENSG00000110066.16(gene)|ensembl:ENST00000304363.9(transcript)|ensembl:ENST00000615954.4(transcript)|go:""GO:0000779""(condensed chromosome, centromeric region)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0007517""(muscle organ development)|go:""GO:0032259""(methylation)|go:""GO:0042054""(histone methyltransferase activity)|go:""GO:0042799""(histone H4K20 methyltransferase activity)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0046872""(metal ion binding)|go:""GO:0140939""(histone H4 methyltransferase activity)|go:""GO:0140941""(histone H4K20me methyltransferase activity)|go:""GO:0140944""(histone H4K20 monomethyltransferase activity)|go:""GO:1904047""(S-adenosyl-L-methionine binding)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044424|interpro:IPR046341|mint:Q4FZB7|rcsb pdb:3S8P|rcsb pdb:5CPR|rcsb pdb:5WBV|rcsb pdb:7YRD|rcsb pdb:7YRG|rcsb pdb:8JHF|rcsb pdb:8JHG|rcsb pdb:8T9F|rcsb pdb:8T9H|reactome:R-HSA-3214841|refseq:NP_001287838.1|refseq:NP_057112.3|refseq:NP_060105.3|refseq:XP_005274092.2|refseq:XP_011543393.1|refseq:XP_011543395.1|refseq:XP_011543396.1|dip:DIP-48656N|panther:PTHR12977(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xLr/ydN4I0qJ46G/8A3JfZqAbyE1392	rogid:PtHlCj2DZzd3IA0joU5M307MqM49606	intact-crc:DF6099ECF4353259|rigid:JtwTOXRLN+axvWTtt+XNKVQs3Wc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PKC3	uniprotkb:A0A2B3Y6C6	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	intact:EBI-2809836|uniprotkb:A0A1V4BKN1|uniprotkb:Q6HS64|uniprotkb:Q6KLG4|uniprotkb:E9R1Z0|uniprotkb:E9R1Z1|uniprotkb:Q81KQ8	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:a0a2b3y6c6_bacan(display_long)|uniprotkb:GBAA_4932(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810865|imex:IM-13779-1483	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"interpro:IPR009293(Protein of unknown function DUF948, bacterial)|go:""GO:0016020""(membrane)|refseq:WP_001197726.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:bq85IyqkiV02z9B9bgDu4A+z+cU1392	intact-crc:D144ED2DA039CDAD|rigid:PAGRDDdZl/dO8HfslxwoJOV1oag	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95793	uniprotkb:A0A6L8P1C8	intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|uniprotkb:E1P5Y1|uniprotkb:E1P608|ensembl:ENSP00000360922.2|uniprotkb:Q5JW29	intact:EBI-2809717|uniprotkb:Q6KX13|uniprotkb:Q6I395|uniprotkb:E9QX61|uniprotkb:E9QX62|uniprotkb:Q81V12|uniprotkb:A0A0J1HPE8	psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym)	psi-mi:a0a6l8p1c8_bacan(display_long)|uniprotkb:GBAA_0692(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810899|imex:IM-13779-1487	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|panther:PTHR46054(orthology-group)|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|ensembl:ENSG00000124214.21(gene)|ensembl:ENST00000371856.7(transcript)|go:""GO:0000512""(lncRNA-mediated post-transcriptional gene silencing)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0007281""(germ cell development)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0030425""(dendrite)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044297""(cell body)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0046726""(positive regulation by virus of viral protein levels in host cell)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098964""(anterograde dendritic transport of messenger ribonucleoprotein complex)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099010""(modification of postsynaptic structure)|go:""GO:1900273""(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|interpro:IPR051740|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY|refseq:XP_005260584.1|refseq:NP_001306063.1|refseq:NP_001306064.1"	refseq:WP_000791491.1|interpro:IPR029062|interpro:IPR039975	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606	rogid:rmCdN8WfYRTzGdoiaYY3DCxiNa01392	intact-crc:CBCF7F75B3D94265|rigid:4GrGTXDYJenTEJA6JymsbwPvONU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:O00560	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-727004|uniprotkb:O43391|uniprotkb:O00173|uniprotkb:Q14CP2|ensembl:ENSP00000260130.4|ensembl:ENSP00000411771.2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810940|imex:IM-13779-1489	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"ensembl:ENSG00000137575.12(gene)|ensembl:ENST00000260130.9(transcript)|ensembl:ENST00000413219.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0005109""(frizzled binding)|go:""GO:0005137""(interleukin-5 receptor binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005895""(interleukin-5 receptor complex)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016020""(membrane)|go:""GO:0019838""(growth factor binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042043""(neurexin family protein binding)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045545""(syndecan binding)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0098793""(presynapse)|go:""GO:0099054""(presynapse assembly)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051230|mint:O00560|rcsb pdb:1N99|rcsb pdb:1NTE|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|rcsb pdb:7FSG|rcsb pdb:7FSH|rcsb pdb:7FSI|rcsb pdb:7FSJ|rcsb pdb:7FSK|rcsb pdb:7FSL|rcsb pdb:7FT5|rcsb pdb:7FSM|rcsb pdb:7FSN|rcsb pdb:7FSO|rcsb pdb:7FSP|rcsb pdb:7FSQ|rcsb pdb:7FSR|rcsb pdb:7FSS|rcsb pdb:7FST|rcsb pdb:7FSU|rcsb pdb:7FSV|rcsb pdb:7FSW|rcsb pdb:7FSX|rcsb pdb:7FSY|rcsb pdb:7FSZ|rcsb pdb:7FT0|rcsb pdb:7FT1|rcsb pdb:7FT2|rcsb pdb:7FT3|rcsb pdb:7FT4|rcsb pdb:7FT6|rcsb pdb:7FT7|rcsb pdb:7FT8|rcsb pdb:7FT9|rcsb pdb:7FTA|rcsb pdb:7FTB|rcsb pdb:7FTC|rcsb pdb:7FTD|rcsb pdb:8AAI|rcsb pdb:8AAK|rcsb pdb:8AAO|rcsb pdb:8AAP|rcsb pdb:8BLU|rcsb pdb:8BLV|rcsb pdb:8HCK|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-6798695|refseq:NP_001007068.1|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|dip:DIP-42705N|panther:PTHR12345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	intact-crc:3424973B2396523A|rigid:LlFMgDsBoubZqHA74iEFE9vzmMg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2P0HLN8	uniprotkb:Q9NY15	intact:EBI-2810906	intact:EBI-2797815|ensembl:ENSP00000312946.6|uniprotkb:Q93072|uniprotkb:Q8IUH1|uniprotkb:Q8IUH0|uniprotkb:A7E297	psi-mi:a0a2p0hln8_bacan(display_long)|uniprotkb:spo0J(gene name)|psi-mi:spo0J(display_short)|uniprotkb:BA_5729(locus name)	psi-mi:stab1_human(display_long)|uniprotkb:Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1(gene name synonym)|uniprotkb:MS-1 antigen(gene name synonym)|uniprotkb:FEEL1(gene name synonym)|uniprotkb:KIAA0246(gene name synonym)|uniprotkb:STAB1(gene name)|psi-mi:STAB1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810912|imex:IM-13779-1485	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050336|interpro:IPR003115(ParB-like nuclease)|interpro:IPR004437(ParB-like partition protein)|interpro:IPR036086|go:""GO:0003677""(DNA binding)|go:""GO:0005694""(chromosome)|go:""GO:0007059""(chromosome segregation)|go:""GO:0045881""(positive regulation of sporulation resulting in formation of a cellular spore)|uniprotkb:A0A2K1VHE8(uniprot-removed-ac)|interpro:IPR041468|refseq:NP_847874.2|refseq:WP_001051841.1"	"ensembl:ENSG00000010327.10(gene)|ensembl:ENST00000321725.10(transcript)|go:""GO:0005041""(low-density lipoprotein particle receptor activity)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005540""(hyaluronic acid binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030169""(low-density lipoprotein particle binding)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0042742""(defense response to bacterium)|interpro:IPR000538(Link)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000782(Beta-Ig-H3/fasciclin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR024731|interpro:IPR036378|mint:Q9NY15|reactome:R-HSA-3000497|refseq:NP_055951.2|panther:PTHR24038(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yZl0oXOncYOEs5/ejxEfcSQuNoE1392	rogid:Y+QVppJrqNJEd2E6wtHqFT+1cII9606	intact-crc:06E50CE839373855|rigid:U02EMx+UDbDB182XsackQYg+kXI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NTJ3	uniprotkb:Q81TW1	intact:EBI-356173|uniprotkb:A6NLT9|uniprotkb:O95752|uniprotkb:Q8NDL4|uniprotkb:Q9UNT9|uniprotkb:D3DNL8|ensembl:ENSP00000341382.5|ensembl:ENSP00000349961.3	intact:EBI-2810929|uniprotkb:Q6I247|uniprotkb:Q6KVY3	psi-mi:smc4_human(display_long)|uniprotkb:SMC4(gene name)|psi-mi:SMC4(display_short)|uniprotkb:CAPC(gene name synonym)|uniprotkb:SMC4L1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym)	psi-mi:adda_bacan(display_long)|uniprotkb:addA(gene name)|psi-mi:addA(display_short)|uniprotkb:DNA 3'-5' helicase AddA(gene name synonym)|uniprotkb:BAS1061(locus name)|uniprotkb:BA_1142(locus name)|uniprotkb:GBAA_1142(locus name)|uniprotkb:ATP-dependent helicase/nuclease AddA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810926|imex:IM-13779-1486	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002800.1|refseq:NP_005487.3|refseq:NP_001275682.1|ensembl:ENSG00000113810.16(gene)|ensembl:ENST00000344722.5(transcript)|ensembl:ENST00000357388.8(transcript)|go:""GO:0000070""(mitotic sister chromatid segregation)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000796""(condensin complex)|go:""GO:0003682""(chromatin binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007076""(mitotic chromosome condensation)|go:""GO:0010032""(meiotic chromosome condensation)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045132""(meiotic chromosome segregation)|go:""GO:0051301""(cell division)|go:""GO:0051383""(kinetochore organization)|go:""GO:0051984""(positive regulation of chromosome segregation)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:1905821""(positive regulation of chromosome condensation)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|mint:Q9NTJ3|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853|refseq:XP_011510613.1|dip:DIP-32946N|panther:PTHR43939(orthology-group)"	"interpro:IPR014152(""DNA helicase (recombination ), AddA type"")|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR038726|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0033202""(DNA helicase complex)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|refseq:WP_000970458.1|refseq:NP_843626.1|refseq:YP_027333.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:+2lnTSgTXZwRawJ/ASBRa6EDgv09606	rogid:mjbRVJQHL4JcpSJqsALgvEqgiMk1392	intact-crc:4A6BDC5FC9162910|rigid:dsHepNqRyIzSymJ+O2BWbvjAZEg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92922	uniprotkb:A0A6L7H1C2	intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480.5	intact:EBI-2809848|uniprotkb:Q6KMV0|uniprotkb:Q6HTL0|uniprotkb:E9QWV5|uniprotkb:E9QWV6|uniprotkb:A0A2P0HIT1|uniprotkb:Q81M57	psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym)	psi-mi:a0a6l7h1c2_bacan(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:GBAA_4397(locus name)|uniprotkb:Recombination protein N(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810919|imex:IM-13779-1488	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003065.3|interpro:IPR032450|ensembl:ENSG00000173473.11(gene)|ensembl:ENST00000254480.10(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0001673""(male germ cell nucleus)|go:""GO:0001741""(XY body)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006337""(nucleosome disassembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030850""(prostate gland development)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035060""(brahma complex)|go:""GO:0042393""(histone binding)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0071564""(npBAF complex)|go:""GO:0071565""(nBAF complex)|go:""GO:0140288""(GBAF complex)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR032448|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR049898|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|reactome:R-HSA-9824585|reactome:R-HSA-9845323|dip:DIP-27545N|dip:DIP-33044N|panther:PTHR12802(orthology-group)"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|refseq:WP_000947756.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606	rogid:aXVFQ2/u7+QhLnMBoqc0Kc6RtX01392	intact-crc:6078274C9EF60B9B|rigid:ZZuFFALFYLW7tRzI1h3Frq9HMPs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PXD8	uniprotkb:O00560	intact:EBI-2810958|uniprotkb:Q6KJQ4|uniprotkb:Q6HQC6|uniprotkb:E9QUX0|uniprotkb:E9QUX1|uniprotkb:A0A2P0HLG3|uniprotkb:Q81JS6	intact:EBI-727004|uniprotkb:O43391|uniprotkb:O00173|uniprotkb:Q14CP2|ensembl:ENSP00000260130.4|ensembl:ENSP00000411771.2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:a0a6l8pxd8_bacan(display_long)|uniprotkb:GBAA_5623(locus name)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810963|imex:IM-13779-1492	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR001264(Glycosyl transferase, family 51)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR050396|interpro:IPR023346|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008658""(penicillin binding)|go:""GO:0008955""(peptidoglycan glycosyltransferase activity)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0071555""(cell wall organization)|refseq:WP_000372993.1|interpro:IPR036950"	"ensembl:ENSG00000137575.12(gene)|ensembl:ENST00000260130.9(transcript)|ensembl:ENST00000413219.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0005109""(frizzled binding)|go:""GO:0005137""(interleukin-5 receptor binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005895""(interleukin-5 receptor complex)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016020""(membrane)|go:""GO:0019838""(growth factor binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042043""(neurexin family protein binding)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045545""(syndecan binding)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0098793""(presynapse)|go:""GO:0099054""(presynapse assembly)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051230|mint:O00560|rcsb pdb:1N99|rcsb pdb:1NTE|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|rcsb pdb:7FSG|rcsb pdb:7FSH|rcsb pdb:7FSI|rcsb pdb:7FSJ|rcsb pdb:7FSK|rcsb pdb:7FSL|rcsb pdb:7FT5|rcsb pdb:7FSM|rcsb pdb:7FSN|rcsb pdb:7FSO|rcsb pdb:7FSP|rcsb pdb:7FSQ|rcsb pdb:7FSR|rcsb pdb:7FSS|rcsb pdb:7FST|rcsb pdb:7FSU|rcsb pdb:7FSV|rcsb pdb:7FSW|rcsb pdb:7FSX|rcsb pdb:7FSY|rcsb pdb:7FSZ|rcsb pdb:7FT0|rcsb pdb:7FT1|rcsb pdb:7FT2|rcsb pdb:7FT3|rcsb pdb:7FT4|rcsb pdb:7FT6|rcsb pdb:7FT7|rcsb pdb:7FT8|rcsb pdb:7FT9|rcsb pdb:7FTA|rcsb pdb:7FTB|rcsb pdb:7FTC|rcsb pdb:7FTD|rcsb pdb:8AAI|rcsb pdb:8AAK|rcsb pdb:8AAO|rcsb pdb:8AAP|rcsb pdb:8BLU|rcsb pdb:8BLV|rcsb pdb:8HCK|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-6798695|refseq:NP_001007068.1|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|dip:DIP-42705N|panther:PTHR12345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:OcEb3PHukIxX0kOwU8P2pZu//q41392	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	intact-crc:735BE6C44023B41E|rigid:LdwYO9Nxs1Q7WOyKlmxfvWnxrCs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00560	uniprotkb:A0A0F7RFX5	intact:EBI-727004|uniprotkb:O43391|uniprotkb:O00173|uniprotkb:Q14CP2|ensembl:ENSP00000260130.4|ensembl:ENSP00000411771.2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	intact:EBI-2810947|uniprotkb:Q6KU61|uniprotkb:E9RBK1|uniprotkb:Q81S07	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:a0a0f7rfx5_bacan(display_long)|uniprotkb:GBAA_1873(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810951|imex:IM-13779-1490	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137575.12(gene)|ensembl:ENST00000260130.9(transcript)|ensembl:ENST00000413219.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0005109""(frizzled binding)|go:""GO:0005137""(interleukin-5 receptor binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005895""(interleukin-5 receptor complex)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016020""(membrane)|go:""GO:0019838""(growth factor binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042043""(neurexin family protein binding)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045545""(syndecan binding)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0098793""(presynapse)|go:""GO:0099054""(presynapse assembly)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051230|mint:O00560|rcsb pdb:1N99|rcsb pdb:1NTE|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|rcsb pdb:7FSG|rcsb pdb:7FSH|rcsb pdb:7FSI|rcsb pdb:7FSJ|rcsb pdb:7FSK|rcsb pdb:7FSL|rcsb pdb:7FT5|rcsb pdb:7FSM|rcsb pdb:7FSN|rcsb pdb:7FSO|rcsb pdb:7FSP|rcsb pdb:7FSQ|rcsb pdb:7FSR|rcsb pdb:7FSS|rcsb pdb:7FST|rcsb pdb:7FSU|rcsb pdb:7FSV|rcsb pdb:7FSW|rcsb pdb:7FSX|rcsb pdb:7FSY|rcsb pdb:7FSZ|rcsb pdb:7FT0|rcsb pdb:7FT1|rcsb pdb:7FT2|rcsb pdb:7FT3|rcsb pdb:7FT4|rcsb pdb:7FT6|rcsb pdb:7FT7|rcsb pdb:7FT8|rcsb pdb:7FT9|rcsb pdb:7FTA|rcsb pdb:7FTB|rcsb pdb:7FTC|rcsb pdb:7FTD|rcsb pdb:8AAI|rcsb pdb:8AAK|rcsb pdb:8AAO|rcsb pdb:8AAP|rcsb pdb:8BLU|rcsb pdb:8BLV|rcsb pdb:8HCK|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-6798695|refseq:NP_001007068.1|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|dip:DIP-42705N|panther:PTHR12345(orthology-group)"	refseq:WP_000939923.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	rogid:7btqhFP46e35lhUMA3JJILGy8tU1392	intact-crc:112FC4F331BCC84D|rigid:0NTV0TprEEtPHl8oJjPr9Zsud4g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N392	uniprotkb:A0A2P0HHN0	intact:EBI-372814|uniprotkb:E1P575|ensembl:ENSP00000357131.2|uniprotkb:Q58EZ3|uniprotkb:Q6P679|uniprotkb:Q6PJD7|uniprotkb:Q96S64|intact:EBI-28984395	intact:EBI-2810973	psi-mi:rhg18_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym)|uniprotkb:MacGAP(gene name synonym)|uniprotkb:ARHGAP18(gene name)|psi-mi:ARHGAP18(display_short)	psi-mi:a0a2p0hhn0_bacan(display_long)|uniprotkb:BA_3818(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810970|imex:IM-13779-1491	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000146376.11(gene)|ensembl:ENST00000368149.3(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016607""(nuclear speck)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q8N392|reactome:R-HSA-8980692|reactome:R-HSA-9013106|refseq:NP_277050.2|panther:PTHR14963(orthology-group)"	"uniprotkb:Q81XV0(uniprot-removed-ac)|interpro:IPR002611(IstB-like ATP-binding protein)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006260""(DNA replication)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:NP_846070.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:24F0Swg/Ye/UfWPt8fJcO+q0nkc9606	rogid:JTcMfCQuMK0eBbE1t1iYq3NVBz41392	intact-crc:528C8ECA3A91D0B4|rigid:mw/twdmq60tiboDTDWi5W6pcTaM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H7X0	uniprotkb:O75787	intact:EBI-2810985	intact:EBI-2512037|uniprotkb:Q8NG15|uniprotkb:Q8NBP3|uniprotkb:Q5QTQ7|uniprotkb:Q9UG89|uniprotkb:Q96FV6|uniprotkb:Q9H2P8|uniprotkb:Q96LB5|uniprotkb:Q6T7F5|uniprotkb:B7Z9I3|ensembl:ENSP00000490083.1	psi-mi:a0a6l7h7x0_bacan(display_long)|uniprotkb:asnO1(gene name)|psi-mi:asnO1(display_short)|uniprotkb:BA_1157(locus name)	"psi-mi:renr_human(display_long)|uniprotkb:ATP6AP2(gene name)|psi-mi:ATP6AP2(display_short)|uniprotkb:ATP6IP2(gene name synonym)|uniprotkb:CAPER(gene name synonym)|uniprotkb:ELDF10(gene name synonym)|uniprotkb:Renin/prorenin receptor(gene name synonym)|uniprotkb:""ATPase H(+)-transporting lysosomal accessory protein 2""(gene name synonym)|uniprotkb:""ATPase H(+)-transporting lysosomal-interacting protein 2""(gene name synonym)|uniprotkb:Vacuolar ATP synthase membrane sector-associated protein M8-9(gene name synonym)|uniprotkb:N14F(gene name synonym)|uniprotkb:Embryonic liver differentiation factor 10(gene name synonym)|uniprotkb:HT028(orf name)|uniprotkb:MSTP009(orf name)|uniprotkb:PSEC0072(orf name)|uniprotkb:ER-localized type I transmembrane adapter(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810982|imex:IM-13779-1493	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A2P0HB98(uniprot-removed-ac)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|refseq:NP_843639.2|interpro:IPR051786|go:""GO:0004066""(""asparagine synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006529""(asparagine biosynthetic process)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:WP_000333975.1"	"efo:""Orphanet:363654""|efo:""Orphanet:93952""|ensembl:ENSG00000182220.15(gene)|ensembl:ENST00000636580.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0002003""(angiotensin maturation)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0021626""(central nervous system maturation)|go:""GO:0021903""(rostrocaudal neural tube patterning)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030424""(axon)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0032591""(dendritic spine membrane)|go:""GO:0032914""(positive regulation of transforming growth factor beta1 production)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0048069""(eye pigmentation)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0051452""(intracellular pH reduction)|go:""GO:0060323""(head morphogenesis)|go:""GO:0061795""(Golgi lumen acidification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR012493(Renin receptor-like)|mint:O75787|rcsb pdb:3LBS|rcsb pdb:3LC8|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:NP_005756.2|panther:PTHR13351(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GYuJtq/zho+XvZ6xGl6acAn9U4k1392	rogid:v4lEPX23LdYqPi8dQX4MZG+tQZg9606	intact-crc:98EE9514247B8D6D|rigid:TiejwKGjVO3i5aQZ80fzMMPH+zw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5TB80	uniprotkb:A0A6L7HRI8	intact:EBI-1059012|uniprotkb:A6PVL7|uniprotkb:A6PVL8|uniprotkb:Q6P475|uniprotkb:Q9Y2L2|ensembl:ENSP00000385215.3	intact:EBI-2810366|uniprotkb:Q6F051	psi-mi:ce162_human(display_long)|uniprotkb:CEP162(gene name)|psi-mi:CEP162(display_short)|uniprotkb:C6orf84(gene name synonym)|uniprotkb:KIAA1009(gene name synonym)|uniprotkb:Protein QN1 homolog(gene name synonym)|uniprotkb:QN1(gene name synonym)	psi-mi:a0a6l7hri8_bacan(display_long)|uniprotkb:GBAA_pXO2_0034(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811002|imex:IM-13779-1496	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273135.1|refseq:NP_055710.2|refseq:XP_016865973.1|refseq:XP_006715443.1|ensembl:ENSG00000135315.12(gene)|ensembl:ENST00000403245.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005879""(axonemal microtubule)|go:""GO:0034451""(centriolar satellite)|go:""GO:0060271""(cilium assembly)|interpro:IPR038774|mint:Q5TB80|reactome:R-HSA-5620912|dip:DIP-50714N|panther:PTHR34031(orthology-group)"	"go:""GO:0016020""(membrane)|refseq:WP_000249505.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HVNIR6cxYzGFkoNEDnEcn1ro7UQ9606	rogid:CttsAiL8z2LvYlOUlkIGYJ7cxoA1392	intact-crc:DB4420A83FD727FC|rigid:4s1xgpX2FcdJZsI2n/3oSeF9iHo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04440	uniprotkb:A0A6L7HFM3	intact:EBI-2802503|uniprotkb:Q9GIM2|uniprotkb:Q5EP47|uniprotkb:Q29682|uniprotkb:Q29879|uniprotkb:B8ZX68|uniprotkb:Q5EP52|uniprotkb:Q29698|uniprotkb:Q29827|uniprotkb:Q5EP46|uniprotkb:Q9XS11|uniprotkb:Q14279|uniprotkb:Q5YLA6|uniprotkb:O19700|uniprotkb:P01916|uniprotkb:B9W5S8|uniprotkb:O98219|uniprotkb:Q29778|uniprotkb:B9W6F9|uniprotkb:O19749|uniprotkb:Q30033|uniprotkb:Q5EP53|uniprotkb:Q9TQE2|uniprotkb:Q9GJ41|uniprotkb:Q29684|uniprotkb:O00259|uniprotkb:Q5I4H9|uniprotkb:A8YPB3|uniprotkb:P04232|uniprotkb:Q5ENE1|uniprotkb:C0MPP5|uniprotkb:Q30174|uniprotkb:Q29880|uniprotkb:Q8HWT5|uniprotkb:Q30052|uniprotkb:Q9TNT7|uniprotkb:Q5SQ73|uniprotkb:Q9BD13|uniprotkb:Q5EP51|uniprotkb:Q4JHD8|uniprotkb:Q860Z7|uniprotkb:Q5ENW3|uniprotkb:A0PFJ7|uniprotkb:Q6LBX3|uniprotkb:Q6LBX7|uniprotkb:B7VF87|uniprotkb:C0MPQ7|uniprotkb:Q30032|uniprotkb:Q9MY67|uniprotkb:Q5ISH4|uniprotkb:Q9XS12|uniprotkb:Q29977|uniprotkb:Q6PWX6|uniprotkb:Q30053|uniprotkb:Q0ZFN3|uniprotkb:Q5EP56|uniprotkb:Q27S71|uniprotkb:Q30050|uniprotkb:P79493|uniprotkb:P79608|uniprotkb:Q6LBX6|uniprotkb:Q0P0L4|uniprotkb:Q6IVX1|uniprotkb:Q30051|uniprotkb:O98216|uniprotkb:A5I886|uniprotkb:Q95IT7|uniprotkb:O98217|uniprotkb:Q29714|uniprotkb:O19698|uniprotkb:B5U8B4|uniprotkb:C5IZL1|uniprotkb:Q4GY31|uniprotkb:Q29775|uniprotkb:Q30054|uniprotkb:B7VF80|uniprotkb:O98215|uniprotkb:B8ZYT0|uniprotkb:Q30055|uniprotkb:Q29776|uniprotkb:C0MPQ5|uniprotkb:Q5STP2|uniprotkb:Q95IT8|uniprotkb:C0MPQ3|uniprotkb:Q6LBX2|uniprotkb:O98223|uniprotkb:C0MPQ6|uniprotkb:Q30034|uniprotkb:O46884|uniprotkb:Q29779|uniprotkb:Q6LBX4|uniprotkb:Q5ISH5|uniprotkb:C0MPQ2|uniprotkb:O19702|uniprotkb:Q8HWL7|uniprotkb:Q9GIX6|uniprotkb:Q29898|uniprotkb:Q2MGW3|uniprotkb:Q6TAS4|uniprotkb:O98218|uniprotkb:Q8SNC4|uniprotkb:Q29828|uniprotkb:Q9GIM4|uniprotkb:O77952|uniprotkb:Q7YQ10|uniprotkb:Q5EP49|uniprotkb:Q714U1|uniprotkb:Q6LBX5|uniprotkb:Q5I4H8|uniprotkb:B9W6F7|uniprotkb:Q95HC1|uniprotkb:P13763|uniprotkb:C4R9J5|uniprotkb:Q5ENE0|uniprotkb:Q30015|uniprotkb:Q30031|uniprotkb:Q29781|uniprotkb:O98222|uniprotkb:Q714U2|ensembl:ENSP00000382422.2|ensembl:ENSP00000389288.2|ensembl:ENSP00000396095.2|ensembl:ENSP00000407674.2|ensembl:ENSP00000408146.2|ensembl:ENSP00000414196.2	intact:EBI-2811019|uniprotkb:Q6HU79|uniprotkb:Q6KNG3|uniprotkb:E9R8X8|uniprotkb:E9R8X9|uniprotkb:Q81MT6|uniprotkb:A0A0F7RCX3	"psi-mi:dpb1_human(display_long)|uniprotkb:HLA-DP1B(gene name synonym)|uniprotkb:""HLA class II histocompatibility antigen, DP(W4) beta chain""(gene name synonym)|uniprotkb:MHC class II antigen DPB1(gene name synonym)|uniprotkb:HLA-DPB1(gene name)|psi-mi:HLA-DPB1(display_short)"	psi-mi:a0a6l7hfm3_bacan(display_long)|uniprotkb:pyc(gene name)|psi-mi:pyc(display_short)|uniprotkb:GBAA_4157(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811016|imex:IM-13779-1497	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000215048.13(gene)|ensembl:ENSG00000223865.12(gene)|ensembl:ENSG00000226826.10(gene)|ensembl:ENSG00000230763.11(gene)|ensembl:ENSG00000236693.11(gene)|ensembl:ENSG00000237710.10(gene)|ensembl:ENST00000399500.6(transcript)|ensembl:ENST00000411749.6(transcript)|ensembl:ENST00000418931.7(transcript)|ensembl:ENST00000425130.6(transcript)|ensembl:ENST00000433800.6(transcript)|ensembl:ENST00000454006.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P04440|rcsb pdb:3LQZ|rcsb pdb:4P4K|rcsb pdb:4P4R|rcsb pdb:4P57|rcsb pdb:4P5K|rcsb pdb:4P5M|rcsb pdb:7T2A|rcsb pdb:7T2B|rcsb pdb:7T2C|rcsb pdb:7T2D|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_002112.3|efo:""Orphanet:133""|efo:""Orphanet:900""|panther:PTHR19944(orthology-group)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011053(Single hybrid motif)|go:""GO:0004736""(pyruvate carboxylase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0046872""(metal ion binding)|interpro:IPR055268|refseq:WP_000164068.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gy8rTenPR8u64fM9Kzl7ocoX3CM9606	rogid:vk3wfrqt2MsmQkUObx8VTjcjDNs1392	intact-crc:D539AFEB334A5CBB|rigid:9cBHdACKNRmnrTEByDNqK1o9bdg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H1G2	uniprotkb:Q2TAL8	intact:EBI-2809927	intact:EBI-2798044|ensembl:ENSP00000350094.2|ensembl:ENSP00000378830.2|ensembl:ENSP00000412870.2|ensembl:ENSP00000412890.1|ensembl:ENSP00000515516.1|ensembl:ENSP00000515573.1|uniprotkb:Q8TEA5|uniprotkb:Q4G0F7|uniprotkb:Q7L621	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	psi-mi:qric1_human(display_long)|uniprotkb:QRICH1(gene name)|psi-mi:QRICH1(display_short)|uniprotkb:Glutamine-rich protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2810995|imex:IM-13779-1494	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"ensembl:ENSG00000198218.12(gene)|ensembl:ENST00000357496.6(transcript)|ensembl:ENST00000395443.7(transcript)|ensembl:ENST00000411682.2(transcript)|ensembl:ENST00000424300.5(transcript)|ensembl:ENST00000703871.1(transcript)|ensembl:ENST00000703942.1(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036499""(PERK-mediated unfolded protein response)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0140467""(integrated stress response signaling)|interpro:IPR021893|interpro:IPR051284|mint:Q2TAL8|refseq:NP_001307509.1|refseq:NP_001307510.1|refseq:NP_001307511.1|refseq:NP_001307512.1|refseq:NP_001307513.1|refseq:NP_001307514.1|refseq:NP_060200.2|refseq:NP_942581.1|refseq:XP_011532165.1|efo:""Orphanet:580940""|panther:PTHR45736(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	rogid:lZutsiEMc3Fpej5M2vhosiQZnoA9606	intact-crc:7E3EFEB43DEBA2D6|rigid:CQ0E+uOdERZnlSTkPhmBOsCofNg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UQC1	uniprotkb:P13423	intact:EBI-354981	intact:EBI-456868|uniprotkb:Q937W2|uniprotkb:Q937W3|uniprotkb:Q9F5R7|uniprotkb:Q9KH69|uniprotkb:Q9RQU2	psi-mi:q9uqc1_human(display_long)|uniprotkb:HSP70-1(gene name)|psi-mi:HSP70-1(display_short)	psi-mi:pag_bacan(display_long)|uniprotkb:PA-83(gene name synonym)|uniprotkb:Anthrax toxins translocating protein(gene name synonym)|uniprotkb:pagA(gene name)|psi-mi:pagA(display_short)|uniprotkb:pag(gene name synonym)|uniprotkb:pXO1-110(locus name)|uniprotkb:BXA0164(locus name)|uniprotkb:GBAA_pXO1_0164(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811009|imex:IM-13779-1495	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR043129"	"mint:P13423|refseq:NP_052806.1|refseq:WP_000746487.1|refseq:WP_000746486.1|refseq:WP_000746488.1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0044533""(obsolete positive regulation of apoptotic process in another organism)|go:""GO:0046872""(metal ion binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0090729""(toxin activity)|interpro:IPR003896(Bacterial exotoxin B)|interpro:IPR011658(PA14)|interpro:IPR027439|interpro:IPR027441|interpro:IPR035088|interpro:IPR035331|interpro:IPR037149|interpro:IPR037524|interpro:IPR048853|rcsb pdb:1ACC|rcsb pdb:1T6B|rcsb pdb:1TZN|rcsb pdb:1TZO|rcsb pdb:3ETB|rcsb pdb:3INO|rcsb pdb:3J9C|rcsb pdb:3KWV|rcsb pdb:3MHZ|rcsb pdb:3Q8A|rcsb pdb:3Q8B|rcsb pdb:3Q8C|rcsb pdb:3Q8E|rcsb pdb:3Q8F|rcsb pdb:3TEW|rcsb pdb:3TEX|rcsb pdb:3TEY|rcsb pdb:3TEZ|rcsb pdb:4EE2|rcsb pdb:4H2A|rcsb pdb:4NAM|rcsb pdb:5FR3|rcsb pdb:6PSN|rcsb pdb:6UJI|rcsb pdb:6UZB|rcsb pdb:6UZD|rcsb pdb:6UZE|rcsb pdb:6VRA|rcsb pdb:6WJJ|rcsb pdb:6ZXJ|rcsb pdb:6ZXK|rcsb pdb:6ZXL|rcsb pdb:7KXR|rcsb pdb:7O85|reactome:R-HSA-5210891|dip:DIP-29841N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5CycxNHAEy8lDjRntw5Gv8eHQGE9606	rogid:xLr/ydN4I0qJ46G/8A3JfZqAbyE1392	intact-crc:C3DCD9E047AD65B0|rigid:/XOg2xYTVpXYCdbhZ00TTCH0opU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96P16	uniprotkb:A0A6L7HIQ7	intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955.4|ensembl:ENSP00000381984.3	intact:EBI-2811048|uniprotkb:Q6HYX8|uniprotkb:Q6KSX7|uniprotkb:E9R7R7|uniprotkb:E9R7R8|uniprotkb:Q81QQ9	psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym)	psi-mi:a0a6l7hiq7_bacan(display_long)|uniprotkb:GBAA_2360(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811054|imex:IM-13779-1499	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|dip:DIP-50901N|ensembl:ENSG00000141425.18(gene)|ensembl:ENST00000357384.8(transcript)|ensembl:ENST00000399022.9(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001111""(RNA polymerase II promoter clearance)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0042802""(identical protein binding)|go:""GO:0097550""(transcription preinitiation complex)|go:""GO:0099122""(RNA polymerase II C-terminal domain binding)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|interpro:IPR047884|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|panther:PTHR12460(orthology-group)"	"interpro:IPR038729|interpro:IPR027417|go:""GO:0004527""(exonuclease activity)|go:""GO:0006302""(double-strand break repair)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_001247439.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606	rogid:qvsnnLvk4Z6RZBH5uYm5/h0yzyM1392	intact-crc:975F82BDF93A1C16|rigid:TwlZ1f5RI2oumpAzBp4IzMV7W9k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q6EZZ9	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2811074|uniprotkb:A0A0F7RMV3	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q6ezz9_bacan(display_long)|uniprotkb:GBAA_pXO1_0017(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811077|imex:IM-13779-1500	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	refseq:WP_000710698.1|interpro:IPR046060	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:4SdwrVISzDbmmK/hByc+kkeK0J41392	intact-crc:AA14DFB0D4B9A4EA|rigid:7RLjns2+YcCK2twu8YQ9myXMG9g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7REH3	uniprotkb:P19838	intact:EBI-2811064|uniprotkb:Q6KPV8|uniprotkb:E9R093|uniprotkb:Q81YE8	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a0f7reh3_bacan(display_long)|uniprotkb:GBAA_3601(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811061|imex:IM-13779-1502	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001116379.1|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR047589	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:kRV2TrznOHMKW2jOg5FKoFx9L+41392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:DE08B7AA19C1AECF|rigid:glcG+649Gs2F87mL07o7woDkJ2A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60831	uniprotkb:A0A6L8PRN6	intact:EBI-2506064|uniprotkb:B2RD20|ensembl:ENSP00000451962.2|ensembl:ENSP00000518158.1	intact:EBI-2809795|uniprotkb:Q6KT17|uniprotkb:E9QTD7|uniprotkb:Q81QV1	psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name)	psi-mi:a0a6l8prn6_bacan(display_long)|uniprotkb:GBAA_2314(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811030|imex:IM-13779-1498	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009144.1|ensembl:ENSG00000243279.4(gene)|ensembl:ENSG00000292222.1(gene)|ensembl:ENST00000553851.3(transcript)|ensembl:ENST00000710261.1(transcript)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0015813""(L-glutamate transmembrane transport)|go:""GO:0016020""(membrane)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|panther:PTHR12859(orthology-group)"	interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR024696|refseq:WP_000249923.1|interpro:IPR051768|interpro:IPR036689	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606	rogid:F/oxRKTzWTtfjzkNdzflVMqhX0s1392	intact-crc:2AC0F713C4E4E407|rigid:TpbGaX3ts1B6keQEZIxrQaEmAkw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P57721	uniprotkb:A0A6L7GZR7	intact:EBI-954627|uniprotkb:Q8N9K6|uniprotkb:Q96EP6|uniprotkb:A8MPS2|uniprotkb:A8MQ26|uniprotkb:B7WNN9|uniprotkb:B7WPC1|intact:EBI-2555264|ensembl:ENSP00000383168.1|ensembl:ENSP00000505796.1	intact:EBI-2811037|uniprotkb:Q6HT99|uniprotkb:E9R942|uniprotkb:A0A0F7R886|uniprotkb:Q6KMJ2	psi-mi:pcbp3_human(display_long)|uniprotkb:PCBP3-overlapping transcript(gene name synonym)|uniprotkb:PCBP3-overlapping transcript 1(gene name synonym)|uniprotkb:PCBP3OT(gene name synonym)|uniprotkb:PCBP3(gene name)|psi-mi:PCBP3(display_short)|uniprotkb:Alpha-CP3(gene name synonym)|uniprotkb:PCBP3-OT1(gene name synonym)	psi-mi:a0a6l7gzr7_bacan(display_long)|uniprotkb:GBAA_4512(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811041|imex:IM-13779-1501	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123613.1|refseq:NP_001335167.1|refseq:NP_001335171.1|refseq:NP_001335173.1|refseq:NP_065389.2|ensembl:ENSG00000183570.17(gene)|ensembl:ENST00000400314.5(transcript)|ensembl:ENST00000681687.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990829""(C-rich single-stranded DNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P57721|panther:PTHR10288(orthology-group)"	"interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017221(Uncharacterised conserved protein UPF0135, NIF3)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|refseq:WP_000036216.1|interpro:IPR015867(Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal)|interpro:IPR036069"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FM/z2+gksm+t2UY+BhMIl/myjqk9606	rogid:QLw+C4toLL3VxZPIV6og9r1Ib9U1392	intact-crc:5ADFBCC5EF276701|rigid:WHd+AelBkxTcnoPbmGxhaUyoGcw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PKS7	uniprotkb:Q13503	intact:EBI-2809705|uniprotkb:Q6HR58|uniprotkb:Q6KKH5|uniprotkb:E9QWF2|uniprotkb:E9QWF3|uniprotkb:A0A2P0HL14|uniprotkb:Q81XC3	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892.3	psi-mi:a0a6l8pks7_bacan(display_long)|uniprotkb:GBAA_5317(locus name)	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811097|imex:IM-13779-1503	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR051310|interpro:IPR025278|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|refseq:WP_000455036.1"	"panther:PTHR13381(orthology-group)|refseq:NP_004255.2|ensembl:ENSG00000152944.9(gene)|ensembl:ENST00000282892.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070847""(core mediator complex)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110|dip:DIP-31471N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:LEAQuRzrOsJwYgZq7QXDmoKrfqM1392	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	intact-crc:52D836105FAF68C3|rigid:GF6nuXxWOVJl9+wwuAoBQie+MEk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NHL6	uniprotkb:A0A6L8P7D1	intact:EBI-2805262|uniprotkb:Q8NHK0|uniprotkb:Q8NHJ9|uniprotkb:O75025|uniprotkb:O75024|uniprotkb:A8MXT0|uniprotkb:A2IXV4|ensembl:ENSP00000480365.1|ensembl:ENSP00000481700.1	intact:EBI-2811104|uniprotkb:Q6I4W5|uniprotkb:Q6KYK9|uniprotkb:E9R7S6|uniprotkb:E9R7S7|uniprotkb:A0A2P0H8R4|uniprotkb:Q81VW1	psi-mi:lirb1_human(display_long)|uniprotkb:ILT2(gene name synonym)|uniprotkb:LIR1(gene name synonym)|uniprotkb:MIR7(gene name synonym)|uniprotkb:CD85 antigen-like family member J(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 2(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 7(gene name synonym)|uniprotkb:LILRB1(gene name)|psi-mi:LILRB1(display_short)	psi-mi:a0a6l8p7d1_bacan(display_long)|uniprotkb:GBAA_0078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811109|imex:IM-13779-1506	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000274669.5(gene)|ensembl:ENSG00000277807.5(gene)|ensembl:ENST00000616408.4(transcript)|ensembl:ENST00000618055.4(transcript)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0002230""(positive regulation of defense response to virus by host)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002309""(T cell proliferation involved in immune response)|rcsb pdb:6EWO|go:""GO:0002719""(negative regulation of cytokine production involved in immune response)|go:""GO:0002764""(immune response-regulating signaling pathway)|go:""GO:0002767""(immune response-inhibiting cell surface receptor signaling pathway)|go:""GO:0002774""(Fc receptor mediated inhibitory signaling pathway)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0009615""(response to virus)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014063""(negative regulation of serotonin secretion)|go:""GO:0023025""(MHC class Ib protein complex binding)|go:""GO:0023029""(MHC class Ib protein binding)|go:""GO:0030107""(HLA-A specific inhibitory MHC class I receptor activity)|go:""GO:0030109""(HLA-B specific inhibitory MHC class I receptor activity)|go:""GO:0031623""(receptor internalization)|go:""GO:0032393""(MHC class I receptor activity)|go:""GO:0032394""(MHC class Ib receptor activity)|go:""GO:0032396""(inhibitory MHC class I receptor activity)|go:""GO:0032688""(negative regulation of interferon-beta production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032693""(negative regulation of interleukin-10 production)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032945""(negative regulation of mononuclear cell proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046636""(negative regulation of alpha-beta T cell activation)|go:""GO:0051607""(defense response to virus)|go:""GO:0051926""(negative regulation of calcium ion transport)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0097028""(dendritic cell differentiation)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:2000669""(negative regulation of dendritic cell apoptotic process)|go:""GO:2001186""(negative regulation of CD8-positive, alpha-beta T cell activation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001193""(positive regulation of gamma-delta T cell activation involved in immune response)|go:""GO:2001199""(negative regulation of dendritic cell differentiation)|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050412|mint:Q8NHL6|rcsb pdb:1G0X|rcsb pdb:1P7Q|rcsb pdb:1UFU|rcsb pdb:1UGN|rcsb pdb:1VDG|rcsb pdb:3D2U|rcsb pdb:4LL9|rcsb pdb:4NO0|rcsb pdb:5KNM|rcsb pdb:6AEE|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6K60|rcsb pdb:6ZDX|rcsb pdb:7KFK|reactome:R-HSA-198933|refseq:NP_001075106.2|refseq:NP_001075107.2|refseq:NP_001075108.2|refseq:NP_001265327.2|refseq:NP_006660.4|refseq:NP_001265328.2|panther:PTHR11738(orthology-group)"	"interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR025542|go:""GO:0005507""(copper ion binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0046870""(cadmium ion binding)|go:""GO:0050897""(cobalt ion binding)|go:""GO:1990169""(stress response to copper ion)|go:""GO:1990170""(stress response to cadmium ion)|refseq:WP_000128392.1|interpro:IPR036876"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:c3bdpF4SePNjbOkhewak+Vj98hU9606	rogid:fFRKcYLwdibEOh2Hhza1iABGP5U1392	intact-crc:EC36C85A2114D436|rigid:vS+hzY3BFSgM1SA771meE+nA93E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y219	uniprotkb:A0A2P0HHU3	intact:EBI-946223|uniprotkb:Q9UE17|uniprotkb:Q9UE99|uniprotkb:Q9UNK8|uniprotkb:Q9Y6P9|uniprotkb:Q9Y6Q0|ensembl:ENSP00000328169.3	intact:EBI-2811119|uniprotkb:Q6KPA1|uniprotkb:E9RCY6|uniprotkb:Q81WX2	psi-mi:jag2_human(display_long)|uniprotkb:JAG2(gene name)|psi-mi:JAG2(display_short)	psi-mi:a0a2p0hhu3_bacan(display_long)|uniprotkb:GBAA_3841(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811116|imex:IM-13779-1504	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002217.3|refseq:NP_660142.1|ensembl:ENSG00000184916.9(gene)|ensembl:ENST00000331782.8(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003016""(respiratory system process)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008083""(growth factor activity)|go:""GO:0009912""(auditory receptor cell fate commitment)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0030154""(cell differentiation)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030217""(T cell differentiation)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042492""(gamma-delta T cell differentiation)|go:""GO:0045061""(thymic T cell selection)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:1990134""(epithelial cell apoptotic process involved in palatal shelf morphogenesis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001774(""Delta/Serrate/lag-2 (DSL) protein"")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026219|interpro:IPR049883|mint:Q9Y219|rcsb pdb:5MW5|rcsb pdb:5MW7|rcsb pdb:5MWF|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-9013507|panther:PTHR24044(orthology-group)"	"interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|go:""GO:0005615""(extracellular space)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|refseq:WP_000092465.1|interpro:IPR048009"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GoH5Lw1zl+3dhA4RSpJTyQ0LY4Q9606	rogid:bOpkW2SnpXGvNsOHSbPKRkQYwxw1392	intact-crc:215A958F751B9355|rigid:qOSodL1Quvxq1COrDbdqA1MDyTo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13772	uniprotkb:Q81SW4	intact:EBI-954501|uniprotkb:Q14239|uniprotkb:B4E260|uniprotkb:E9PAV7|uniprotkb:J3KQN8|uniprotkb:A8K8W5|intact:EBI-28971630|ensembl:ENSP00000462943.1|ensembl:ENSP00000463476.1|ensembl:ENSP00000464054.1	intact:EBI-2811087|uniprotkb:Q6I143|uniprotkb:Q6KUZ7|uniprotkb:E9QV53|uniprotkb:E9QV54	psi-mi:ncoa4_human(display_long)|uniprotkb:Androgen receptor-associated protein of 70 kDa(gene name synonym)|uniprotkb:Ret-activating protein ELE1(gene name synonym)|uniprotkb:NCOA4(gene name)|psi-mi:NCOA4(display_short)|uniprotkb:ARA70(gene name synonym)|uniprotkb:ELE1(gene name synonym)|uniprotkb:RFG(gene name synonym)|uniprotkb:Androgen receptor coactivator 70 kDa protein(gene name synonym)|uniprotkb:Ferritin cargo receptor NCOA4(gene name synonym)	psi-mi:sp4a_bacan(display_long)|uniprotkb:spoIVA(gene name)|psi-mi:spoIVA(display_short)|uniprotkb:Coat morphogenetic protein SpoIVA(gene name synonym)|uniprotkb:BAS1419(locus name)|uniprotkb:BA_1530(locus name)|uniprotkb:GBAA_1530(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811084|imex:IM-13779-1505	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:146""|dip:DIP-5957N|ensembl:ENSG00000266412.6(gene)|ensembl:ENST00000581486.6(transcript)|ensembl:ENST00000583565.5(transcript)|ensembl:ENST00000585132.5(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005776""(autophagosome)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0008584""(male gonad development)|go:""GO:0009725""(response to hormone)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0044754""(autolysosome)|go:""GO:0071391""(cellular response to estrogen stimulus)|go:""GO:0071394""(cellular response to testosterone stimulus)|interpro:IPR022174|interpro:IPR039947|rcsb pdb:1T5Z|rcsb pdb:8QU9|reactome:R-HSA-9841922|refseq:NP_001138732.1|refseq:NP_001138733.1|refseq:NP_001138734.1|refseq:NP_001138735.1|refseq:NP_005428.1|panther:PTHR17085(orthology-group)"	"interpro:IPR014201(Sporulation stage IV, protein A)|interpro:IPR027417|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030435""(sporulation resulting in formation of a cellular spore)|go:""GO:0031160""(spore wall)|go:""GO:0042244""(spore wall assembly)|go:""GO:0042601""(endospore-forming forespore)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070499""(exosporium assembly)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|refseq:WP_000416519.1|refseq:YP_027688.1|refseq:NP_843981.1|interpro:IPR046840|interpro:IPR046841|interpro:IPR046842"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/NfEP88wxWvTac5UcLWx2WJend89606	rogid:iPDW6vKDNWNkkAUf22hjfqaPdks1392	intact-crc:9B53044A31B58ADF|rigid:DbhBEkrH7uObROS3vHlX1lCwh24	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:Q8IWJ2	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-1645320|uniprotkb:O15045|uniprotkb:Q4ZG46|uniprotkb:Q8TDH3|uniprotkb:Q9H2G8|uniprotkb:A6H8X8|intact:EBI-1645335|ensembl:ENSP00000307939.5|intact:EBI-28984280	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:gcc2_human(display_long)|uniprotkb:GCC2(gene name)|psi-mi:GCC2(display_short)|uniprotkb:KIAA0336(gene name synonym)|uniprotkb:RANBP2L4(gene name synonym)|uniprotkb:185 kDa Golgi coiled-coil protein(gene name synonym)|uniprotkb:Ran-binding protein 2-like 4(gene name synonym)|uniprotkb:CTCL tumor antigen se1-1(gene name synonym)|uniprotkb:CLL-associated antigen KW-11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-53(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811168|imex:IM-13779-1508	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"refseq:NP_852118.1|refseq:XP_006712934.1|ensembl:ENSG00000135968.22(gene)|ensembl:ENST00000309863.11(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0016020""(membrane)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0034499""(late endosome to Golgi transport)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0070861""(regulation of protein exit from endoplasmic reticulum)|go:""GO:0071955""(recycling endosome to Golgi transport)|go:""GO:0090161""(Golgi ribbon formation)|interpro:IPR000237(GRIP)|interpro:IPR032023|interpro:IPR051841|rcsb pdb:3BBP|reactome:R-HSA-6811440|reactome:R-HSA-9725370|panther:PTHR18902(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:YeL/V7QABi3DbamH+qE6WfFLAco9606	intact-crc:9D955F2E3AC496DB|rigid:QXQOHq7F8WtIkWvNVNWjjzlqzyw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43464	uniprotkb:A0A6L7H5N1	intact:EBI-517086|uniprotkb:Q9HBZ4|uniprotkb:Q9P0Y3|uniprotkb:Q9P0Y4|ensembl:ENSP00000258080.3	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:htra2_human(display_long)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)|uniprotkb:HTRA2(gene name)|psi-mi:HTRA2(display_short)|uniprotkb:PRSS25(gene name synonym)|uniprotkb:OMI(gene name synonym)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811127|imex:IM-13779-1509	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2828""|efo:""Orphanet:505208""|ensembl:ENSG00000115317.13(gene)|ensembl:ENST00000258080.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006508""(proteolysis)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007628""(adult walking behavior)|go:""GO:0008233""(peptidase activity)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009635""(response to herbicide)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0012501""(programmed cell death)|go:""GO:0016020""(membrane)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0019742""(pentacyclic triterpenoid metabolic process)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030291""(protein serine/threonine kinase inhibitor activity)|go:""GO:0030900""(forebrain development)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0048666""(neuron development)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:1905090""(negative regulation of type 2 mitophagy)|go:""GO:1905370""(serine-type endopeptidase complex)|go:""GO:1990948""(ubiquitin ligase inhibitor activity)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001241""(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:O43464|rcsb pdb:1LCY|rcsb pdb:2PZD|rcsb pdb:5FHT|rcsb pdb:5M3N|rcsb pdb:5M3O|rcsb pdb:5TNY|rcsb pdb:5TNZ|rcsb pdb:5TO0|rcsb pdb:5TO1|rcsb pdb:5WYN|rcsb pdb:7VGE|rcsb pdb:8AUK|rcsb pdb:8E2K|reactome:R-HSA-9837999|reactome:R-HSA-9841251|refseq:NP_001308656.1|refseq:NP_037379.1|refseq:NP_659540.1|panther:PTHR22939(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IaLYfoH7H9K64U0KrEY7iB1vAfU9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:B3C46CE443F5FCD0|rigid:P6lYo/qNC7lvPU4LkQI9il9anHM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00165	uniprotkb:A0A0F7R9R7	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	intact:EBI-2811159	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:a0a0f7r9r7_bacan(display_long)|uniprotkb:BA_5304(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811156|imex:IM-13779-1510	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	uniprotkb:Q81XD5(uniprot-removed-ac)|interpro:IPR004954(Peptidase M60, viral enhancin protein)|refseq:NP_847481.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rogid:+2A2K0JZVOaQ/UaFJyV7O41Bvos1392	intact-crc:EB7509902611CA04|rigid:1AI0ni4tzVz5CXW9o6NWUgMDyxs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81S26	uniprotkb:P30511	intact:EBI-2811143|uniprotkb:Q6KU79|uniprotkb:Q6I0A5	intact:EBI-2811134|uniprotkb:Q5SPT5|uniprotkb:Q9TP68|uniprotkb:Q8WLP5|uniprotkb:Q860R0|uniprotkb:Q5JQJ1|uniprotkb:Q8MGQ1|uniprotkb:Q95HC0|uniprotkb:Q5JQI8|ensembl:ENSP00000334263.4|ensembl:ENSP00000366057.1	psi-mi:ilvd_bacan(display_long)|uniprotkb:ilvD(gene name)|psi-mi:ilvD(display_short)|uniprotkb:BA_1853(locus name)|uniprotkb:GBAA_1853(locus name)|uniprotkb:BAS1717(locus name)	psi-mi:hlaf_human(display_long)|uniprotkb:HLA-F(gene name)|psi-mi:HLA-F(display_short)|uniprotkb:HLA-5.4(gene name synonym)|uniprotkb:HLAF(gene name synonym)|uniprotkb:CDA12(gene name synonym)|uniprotkb:HLA F antigen(gene name synonym)|uniprotkb:Leukocyte antigen F(gene name synonym)|uniprotkb:MHC class I antigen F(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811149|imex:IM-13779-1507	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004404(Dihydroxy-acid dehydratase)|interpro:IPR000581(Dihydroxy-acid and 6-phosphogluconate dehydratase)|interpro:IPR020558|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004160""(dihydroxy-acid dehydratase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|refseq:WP_001255799.1|interpro:IPR037237|interpro:IPR042096|refseq:NP_844270.1|refseq:YP_027982.1"	"refseq:NP_001091948.1|refseq:NP_001091949.1|refseq:NP_061823.2|ensembl:ENSG00000204642.14(gene)|ensembl:ENST00000334668.8(transcript)|ensembl:ENST00000376861.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002477""(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002725""(negative regulation of T cell cytokine production)|go:""GO:0002728""(negative regulation of natural killer cell cytokine production)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032398""(MHC class Ib protein complex)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0043322""(negative regulation of natural killer cell degranulation)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046978""(TAP1 binding)|go:""GO:0046979""(TAP2 binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P30511|rcsb pdb:5IUE|rcsb pdb:5KNM|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|panther:PTHR16675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2rwY7biS4Is4mpOU8lcawsTzqSU1392	rogid:rbmQdah7wpa+IyDjP5vDlIA+heM9606	intact-crc:1C04F4E08C117690|rigid:T/+YVuy85Mghs7ERoCu/H2/zcM8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P9C4	uniprotkb:O00273	intact:EBI-2811209|uniprotkb:A0A0J1HL43|uniprotkb:Q6KYM3|uniprotkb:Q6I4X9|uniprotkb:E9R1T0|uniprotkb:E9R1T1|uniprotkb:Q81VX5|uniprotkb:A0A347ZXP1	intact:EBI-727171|uniprotkb:Q96I97|uniprotkb:Q9Y6C6|uniprotkb:Q5T6G6|uniprotkb:Q5T6G5|ensembl:ENSP00000366237.3	psi-mi:a0a6l8p9c4_bacan(display_long)|uniprotkb:ftsH(gene name)|psi-mi:ftsH(display_short)|uniprotkb:GBAA_0064(locus name)	psi-mi:dffa_human(display_long)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym)|uniprotkb:DFFA(gene name)|psi-mi:DFFA(display_short)|uniprotkb:DFF1(gene name synonym)|uniprotkb:DFF45(gene name synonym)|uniprotkb:H13(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811206|imex:IM-13779-1512	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR000642(Peptidase M41)|interpro:IPR027417|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0051301""(cell division)|refseq:WP_001079659.1|interpro:IPR037219|interpro:IPR041569"	"refseq:NP_004392.1|refseq:NP_998731.1|ensembl:ENSG00000160049.12(gene)|ensembl:ENST00000377038.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006309""(apoptotic DNA fragmentation)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0032076""(negative regulation of deoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0060703""(deoxyribonuclease inhibitor activity)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070242""(thymocyte apoptotic process)|go:""GO:1900118""(negative regulation of execution phase of apoptosis)|go:""GO:1902511""(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|mint:O00273|rcsb pdb:1IBX|rcsb pdb:1IYR|rcsb pdb:1KOY|reactome:R-HSA-140342|panther:PTHR12306(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZOptq4R8kaVv+70fzRZGncFxnbY1392	rogid:jz7MT9TaqFl1lwoITptPZ3P2KVY9606	intact-crc:E3876F8DE34FFD43|rigid:fOA0LpVa+mBDt2J3SIkrtiaeN5M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6P2E9	uniprotkb:A0A6L8PFQ4	intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811.5	intact:EBI-2811194|uniprotkb:Q6KKD9|uniprotkb:Q6HR20|uniprotkb:E9RDA5|uniprotkb:E9RDA6|uniprotkb:Q81X84|uniprotkb:A0A0F7R5R3	psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym)	psi-mi:a0a6l8pfq4_bacan(display_long)|uniprotkb:GBAA_5358(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811199|imex:IM-13779-1514	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055144.3|dip:DIP-31192N|ensembl:ENSG00000038358.15(gene)|ensembl:ENST00000358933.10(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0031087""(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|interpro:IPR036322|interpro:IPR044938|interpro:IPR045152|interpro:IPR049404|mint:Q6P2E9|reactome:R-HSA-430039|panther:PTHR15598(orthology-group)"	interpro:IPR006944(Phage portal protein)|interpro:IPR006427(Phage portal protein, HK97)|refseq:WP_000522484.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606	rogid:dfclSVwADmsN1LvBduNOVnRZ0DA1392	intact-crc:45F46A9A2B3B0888|rigid:48NGTvxmZq2A5jruXyNrQBCQ77E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P32519	uniprotkb:A0A6L7H5N1	intact:EBI-765526|uniprotkb:Q9UDE1|uniprotkb:Q8N6F6|ensembl:ENSP00000239882.3|uniprotkb:B4E2I5|uniprotkb:E9PDQ9	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:elf1_human(display_long)|uniprotkb:E74-like factor 1(gene name synonym)|uniprotkb:ELF1(gene name)|psi-mi:ELF1(display_short)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811187|imex:IM-13779-1511	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_758961.1|ensembl:ENSG00000120690.17(gene)|ensembl:ENST00000239882.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR022084|interpro:IPR036388|interpro:IPR036390|interpro:IPR046328|mint:P32519|rcsb pdb:8BZM|reactome:R-HSA-8939245|reactome:R-HSA-8939247|refseq:NP_001138825.1|refseq:XP_005266333.1|refseq:XP_005266334.1|refseq:XP_011533252.1|refseq:XP_016875898.1|refseq:XP_016875899.1|refseq:XP_016875900.1|refseq:XP_016875901.1|refseq:XP_016875902.1|dip:DIP-185N|panther:PTHR11849(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bkNv2VvMBvrmLtvw8qhFrj9Zgqg9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:5DBAB37FD4E0CA85|rigid:vBMkTram1e0M0mmlUe48hZdoBU0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60861	uniprotkb:A0A4Y1WC41	intact:EBI-2683717|uniprotkb:Q53Y77|uniprotkb:B2RCK9|uniprotkb:Q7Z571|uniprotkb:O43144|uniprotkb:A8KAC2|ensembl:ENSP00000407552.2	intact:EBI-2811175|uniprotkb:Q6KLQ4|uniprotkb:E9QTZ5|uniprotkb:Q81L03	psi-mi:gas7_human(display_long)|uniprotkb:KIAA0394(gene name synonym)|uniprotkb:GAS7(gene name)|psi-mi:GAS7(display_short)	psi-mi:a0a4y1wc41_bacan(display_long)|uniprotkb:polA(gene name)|psi-mi:polA(display_short)|uniprotkb:GBAA_4831(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811180|imex:IM-13779-1513	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011522346.1|refseq:NP_003635.2|refseq:NP_958836.1|refseq:NP_958839.1|refseq:NP_001124303.1|refseq:XP_005256888.1|refseq:XP_005256889.1|refseq:XP_016880728.1|ensembl:ENSG00000007237.19(gene)|ensembl:ENST00000432992.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0042802""(identical protein binding)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051015""(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036020|interpro:IPR036028|interpro:IPR037957|mint:O60861|rcsb pdb:2LX7|rcsb pdb:2YSH|panther:PTHR23065(orthology-group)"	"interpro:IPR043502|interpro:IPR018320|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR020046|interpro:IPR020045|interpro:IPR002421(5'-3' exonuclease)|interpro:IPR019760|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR002298(DNA polymerase A)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR029060|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006302""(double-strand break repair)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0008409""(5'-3' exonuclease activity)|interpro:IPR054690|refseq:WP_000412819.1|interpro:IPR036279|interpro:IPR036397"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AGTjGZ7Nb4FN05kKzZ7POn5n+xQ9606	rogid:gn81BLwvkwoLgpPMLb4rhkwHVHg1392	intact-crc:76B33FF220D2A674|rigid:HQu+2kchHN1/uTLZflGqegeIYQc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35222	uniprotkb:Q81JT7	intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|uniprotkb:A8K1L7|ensembl:ENSP00000344456.5|ensembl:ENSP00000379486.3|ensembl:ENSP00000379488.3|ensembl:ENSP00000385604.1|ensembl:ENSP00000387455.2|ensembl:ENSP00000401599.2|ensembl:ENSP00000409302.2|ensembl:ENSP00000412219.2|ensembl:ENSP00000493533.1|ensembl:ENSP00000493583.2|ensembl:ENSP00000493610.1|ensembl:ENSP00000494053.1|ensembl:ENSP00000494411.1|ensembl:ENSP00000494677.1|ensembl:ENSP00000494845.1|ensembl:ENSP00000494914.1|ensembl:ENSP00000495076.1|ensembl:ENSP00000495244.1|ensembl:ENSP00000495360.1|ensembl:ENSP00000495450.1|ensembl:ENSP00000495719.1|ensembl:ENSP00000495992.1|ensembl:ENSP00000496021.1|ensembl:ENSP00000496180.1|ensembl:ENSP00000496385.1|intact:EBI-491563	intact:EBI-2811219|uniprotkb:Q6KJR4|uniprotkb:Q6HQD6	psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym)	psi-mi:syr1_bacan(display_long)|uniprotkb:argS1(gene name)|psi-mi:argS1(display_short)|uniprotkb:Arginyl-tRNA synthetase 1(gene name synonym)|uniprotkb:BAS5213(locus name)|uniprotkb:BA_5611(locus name)|uniprotkb:GBAA_5611(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811225|imex:IM-13779-1515	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168036.19(gene)|ensembl:ENST00000349496.11(transcript)|ensembl:ENST00000396183.7(transcript)|ensembl:ENST00000396185.8(transcript)|ensembl:ENST00000405570.6(transcript)|ensembl:ENST00000431914.6(transcript)|ensembl:ENST00000433400.6(transcript)|ensembl:ENST00000441708.2(transcript)|ensembl:ENST00000450969.6(transcript)|ensembl:ENST00000642248.1(transcript)|ensembl:ENST00000642315.1(transcript)|ensembl:ENST00000642426.1(transcript)|ensembl:ENST00000642992.1(transcript)|ensembl:ENST00000643031.1(transcript)|ensembl:ENST00000643297.1(transcript)|ensembl:ENST00000643541.1(transcript)|ensembl:ENST00000643977.1(transcript)|ensembl:ENST00000643992.1(transcript)|ensembl:ENST00000644867.1(transcript)|ensembl:ENST00000645210.1(transcript)|ensembl:ENST00000645320.1(transcript)|ensembl:ENST00000645982.1(transcript)|ensembl:ENST00000646369.1(transcript)|ensembl:ENST00000646725.1(transcript)|ensembl:ENST00000647390.1(transcript)|ensembl:ENST00000647413.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000578""(embryonic axis specification)|go:""GO:0000791""(euchromatin)|go:""GO:0000922""(spindle pole)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0001569""(branching involved in blood vessel morphogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001658""(branching involved in ureteric bud morphogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001708""(cell fate specification)|go:""GO:0001711""(endodermal cell fate commitment)|go:""GO:0001764""(neuron migration)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001840""(neural plate development)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0002053""(positive regulation of mesenchymal cell proliferation)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0002089""(lens morphogenesis in camera-type eye)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003266""(regulation of secondary heart field cardioblast proliferation)|go:""GO:0003338""(metanephros morphogenesis)|go:""GO:0003340""(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005916""(fascia adherens)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007398""(ectoderm development)|go:""GO:0007403""(glial cell fate determination)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0009950""(dorsal/ventral axis specification)|go:""GO:0009954""(proximal/distal pattern formation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010909""(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016342""(catenin complex)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0016600""(flotillin complex)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021819""(layer formation in cerebral cortex)|go:""GO:0021854""(hypothalamus development)|go:""GO:0022009""(central nervous system vasculogenesis)|go:""GO:0030018""(Z disc)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030539""(male genitalia development)|go:""GO:0030877""(beta-catenin destruction complex)|go:""GO:0030902""(hindbrain development)|go:""GO:0030997""(regulation of centriole-centriole cohesion)|go:""GO:0031016""(pancreas development)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031528""(microvillus membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031641""(regulation of myelination)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0032355""(response to estradiol)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034750""(Scrib-APC-beta-catenin complex)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0035112""(genitalia morphogenesis)|go:""GO:0035115""(embryonic forelimb morphogenesis)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035315""(hair cell differentiation)|go:""GO:0035995""(detection of muscle stretch)|go:""GO:0036023""(embryonic skeletal limb joint morphogenesis)|go:""GO:0036520""(astrocyte-dopaminergic neuron signaling)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0044338""(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:""GO:0045177""(apical part of cell)|go:""GO:0045202""(synapse)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045453""(bone resorption)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045603""(positive regulation of endothelial cell differentiation)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0045743""(positive regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045976""(negative regulation of mitotic cell cycle, embryonic)|go:""GO:0046332""(SMAD binding)|go:""GO:0048145""(regulation of fibroblast proliferation)|go:""GO:0048469""(cell maturation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0048538""(thymus development)|go:""GO:0048599""(oocyte development)|go:""GO:0048617""(embryonic foregut morphogenesis)|go:""GO:0048643""(positive regulation of skeletal muscle tissue development)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0048664""(neuron fate determination)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048715""(negative regulation of oligodendrocyte differentiation)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0050808""(synapse organization)|go:""GO:0051145""(smooth muscle cell differentiation)|go:""GO:0051450""(myoblast proliferation)|go:""GO:0051884""(regulation of timing of anagen)|go:""GO:0051963""(regulation of synapse assembly)|go:""GO:0060066""(oviduct development)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060440""(trachea formation)|go:""GO:0060441""(epithelial tube branching involved in lung morphogenesis)|go:""GO:0060484""(lung-associated mesenchyme development)|go:""GO:0060487""(lung epithelial cell differentiation)|go:""GO:0060492""(lung induction)|go:""GO:0060742""(epithelial cell differentiation involved in prostate gland development)|go:""GO:0060767""(epithelial cell proliferation involved in prostate gland development)|go:""GO:0060769""(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:0060789""(hair follicle placode formation)|go:""GO:0060856""(establishment of blood-brain barrier)|go:""GO:0060916""(mesenchymal cell proliferation involved in lung development)|go:""GO:0061047""(positive regulation of branching involved in lung morphogenesis)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0061198""(fungiform papilla formation)|go:""GO:0061549""(sympathetic ganglion development)|go:""GO:0061550""(cranial ganglion development)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070369""(beta-catenin-TCF7L2 complex)|go:""GO:0070411""(I-SMAD binding)|go:""GO:0070602""(regulation of centromeric sister chromatid cohesion)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0071944""(cell periphery)|go:""GO:0072033""(renal vesicle formation)|go:""GO:0072053""(renal inner medulla development)|go:""GO:0072054""(renal outer medulla development)|go:""GO:0072079""(nephron tubule formation)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0072182""(regulation of nephron tubule epithelial cell differentiation)|go:""GO:0072497""(mesenchymal stem cell differentiation)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0090279""(regulation of calcium ion import)|go:""GO:0090425""(acinar cell differentiation)|go:""GO:0097091""(synaptic vesicle clustering)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098831""(presynaptic active zone cytoplasmic component)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1901331""(positive regulation of odontoblast differentiation)|go:""GO:1903377""(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:""GO:1904888""(cranial skeletal system development)|go:""GO:1904948""(midbrain dopaminergic neuron differentiation)|go:""GO:1990138""(neuron projection extension)|go:""GO:1990226""(histone methyltransferase binding)|go:""GO:1990403""(embryonic brain development)|go:""GO:1990711""(beta-catenin-ICAT complex)|go:""GO:1990791""(dorsal root ganglion development)|go:""GO:1990907""(beta-catenin-TCF complex)|go:""GO:1990909""(Wnt signalosome)|go:""GO:1990963""(establishment of blood-retinal barrier)|go:""GO:2000008""(regulation of protein localization to cell surface)|go:""GO:2000017""(positive regulation of determination of dorsal identity)|go:""GO:2000288""(positive regulation of myoblast proliferation)|go:""GO:2000648""(positive regulation of stem cell proliferation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|rcsb pdb:7AR4|rcsb pdb:7UWI|rcsb pdb:7UWO|rcsb pdb:7ZRB|rcsb pdb:8EI9|rcsb pdb:8EIA|rcsb pdb:8EIB|rcsb pdb:8EIC|rcsb pdb:8RU3|rcsb pdb:8RU4|rcsb pdb:8VME|rcsb pdb:8VMF|rcsb pdb:8Y0G|rcsb pdb:8Y0P|rcsb pdb:8Y14|rcsb pdb:8Z0U|rcsb pdb:8Z10|rcsb pdb:8Z5J|rcsb pdb:8Z61|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|reactome:R-HSA-3134973|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|reactome:R-HSA-9733709|reactome:R-HSA-9754189|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9793380|reactome:R-HSA-9796292|reactome:R-HSA-9823730|reactome:R-HSA-9824272|reactome:R-HSA-9824585|reactome:R-HSA-9825892|reactome:R-HSA-9830364|reactome:R-HSA-9833576|reactome:R-HSA-9834899|reactome:R-HSA-9856530|reactome:R-HSA-9856649|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1|efo:""Orphanet:1501""|efo:""Orphanet:210159""|efo:""Orphanet:33402""|efo:""Orphanet:404473""|efo:""Orphanet:54595""|efo:""Orphanet:569248""|efo:""Orphanet:873""|efo:""Orphanet:891""|efo:""Orphanet:91414""|dip:DIP-122N|panther:PTHR45976(orthology-group)|ensembl:ENSP00000344456.5|ensembl:ENSP00000379486.3|ensembl:ENSP00000379488.3|ensembl:ENSP00000385604.1|ensembl:ENSP00000412219.2|ensembl:ENSP00000387455.2|ensembl:ENSP00000401599.2|ensembl:ENSP00000409302.2|ensembl:ENSP00000495244.1|ensembl:ENSP00000495076.1|ensembl:ENSP00000495719.1|ensembl:ENSP00000496385.1|ensembl:ENSP00000495450.1|ensembl:ENSP00000494677.1|ensembl:ENSP00000494411.1|ensembl:ENSP00000494053.1|ensembl:ENSP00000493610.1|ensembl:ENSP00000495992.1|ensembl:ENSP00000496180.1|ensembl:ENSP00000495360.1|ensembl:ENSP00000494845.1|ensembl:ENSP00000494914.1|ensembl:ENSP00000496021.1|ensembl:ENSP00000493533.1|ensembl:ENSP00000493583.2"	"interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|go:""GO:0004814""(arginine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006420""(arginyl-tRNA aminoacylation)|refseq:WP_001086469.1|interpro:IPR035684|interpro:IPR036695|refseq:NP_847763.1|refseq:YP_031452.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606	rogid:urOvROG9PysHxGQNMzj+KR6g2Qk1392	intact-crc:3FE3E343056D7AF8|rigid:Xd1SXzO5Ba0HtDXaWofs+fWdtLg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2B6C7W6	uniprotkb:Q9Y224	intact:EBI-2811245|uniprotkb:Q6KLL4|uniprotkb:Q6HSB8|uniprotkb:A0A0J1HW79|uniprotkb:E9QRC1|uniprotkb:E9QRC2|uniprotkb:Q81KW2|uniprotkb:A0A2A7DCA6	intact:EBI-1104547|ensembl:ENSP00000261700.3	psi-mi:a0a2b6c7w6_bacan(display_long)|uniprotkb:GBAA_4875(locus name)	psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811250|imex:IM-13779-1517	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR006015(""Universal stress protein (Usp)"")|interpro:IPR006016(UspA)|refseq:WP_001066673.1"	"refseq:NP_057123.1|ensembl:ENSG00000087302.9(gene)|ensembl:ENST00000261700.8(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006388""(tRNA splicing, via endonucleolytic cleavage and ligation)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050658""(RNA transport)|go:""GO:0072669""(tRNA-splicing ligase complex)|go:""GO:0072686""(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|rcsb pdb:7P3A|reactome:R-HSA-6784531|panther:PTHR15924(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ip9DJeDXmkMaUZrrECiLvAbLiGs1392	rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606	intact-crc:F88D6EA091D63091|rigid:GIaLoaDB33cX/KS5Du3hz0umBMw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P02462	uniprotkb:A0A2P0HGH1	intact:EBI-2432478|uniprotkb:B1AM70|uniprotkb:A7E2W4|uniprotkb:Q1P9S9|uniprotkb:Q5VWF6|uniprotkb:Q86X41|uniprotkb:Q8NF88|uniprotkb:Q9NYC5|uniprotkb:F5H5K0|ensembl:ENSP00000364979.4	intact:EBI-2811235	psi-mi:co4a1_human(display_long)|uniprotkb:COL4A1(gene name)|psi-mi:COL4A1(display_short)	psi-mi:a0a2p0hgh1_bacan(display_long)|uniprotkb:zwf(gene name)|psi-mi:zwf(display_short)|uniprotkb:BA_3433(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811232|imex:IM-13779-1516	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000187498.17(gene)|ensembl:ENST00000375820.10(transcript)|go:""GO:0001569""(branching involved in blood vessel morphogenesis)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005587""(collagen type IV trimer)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007420""(brain development)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0038063""(collagen-activated tyrosine kinase receptor signaling pathway)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048514""(blood vessel morphogenesis)|go:""GO:0061304""(retinal blood vessel morphogenesis)|go:""GO:0061333""(renal tubule morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071711""(basement membrane organization)|interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036954|interpro:IPR050149|mint:P02462|rcsb pdb:1LI1|rcsb pdb:5NAX|rcsb pdb:5NAY|rcsb pdb:6MPX|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8948216|refseq:NP_001290039.1|refseq:NP_001836.3|efo:""Orphanet:36383""|efo:""Orphanet:477749""|efo:""Orphanet:481986""|efo:""Orphanet:73229""|efo:""Orphanet:75326""|efo:""Orphanet:899""|efo:""Orphanet:99810""|panther:PTHR24023(orthology-group)"	"interpro:IPR001282(Glucose-6-phosphate dehydrogenase)|interpro:IPR022674|interpro:IPR022675|interpro:IPR036291|refseq:NP_845717.2|refseq:WP_000445337.1|go:""GO:0004345""(glucose-6-phosphate dehydrogenase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0009051""(pentose-phosphate shunt, oxidative branch)|go:""GO:0050661""(NADP binding)|uniprotkb:A0A0F7RG58(uniprot-removed-ac)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/U3Xsl1lPZnPBfd1cRVDqtuvVb49606	rogid:73Fn1AzTH7zV/B/yaTuxmlvd3+M1392	intact-crc:6CF555C849BF77B8|rigid:gKE3LnKufW99txxoYn6vZNfDpYo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43747	uniprotkb:A0A6L7H5N1	intact:EBI-447609|uniprotkb:O75709|uniprotkb:O75842|uniprotkb:Q9UG09|uniprotkb:Q9Y3U4|ensembl:ENSP00000299980.4|ensembl:ENSP00000454523.1	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:ap1g1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit gamma-1(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin subunit gamma-1(gene name synonym)|uniprotkb:Gamma1-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 gamma-1 large chain(gene name synonym)|uniprotkb:AP1G1(gene name)|psi-mi:AP1G1(display_short)|uniprotkb:ADTG(gene name synonym)|uniprotkb:CLAPG1(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit gamma-1(gene name synonym)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811290|imex:IM-13779-1521	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166747.13(gene)|ensembl:ENST00000299980.9(transcript)|ensembl:ENST00000569748.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005518""(collagen binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0016020""(membrane)|go:""GO:0016182""(synaptic vesicle budding from endosome)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019894""(kinesin binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032438""(melanosome organization)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0055037""(recycling endosome)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0098793""(presynapse)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|interpro:IPR050840|mint:O43747|rcsb pdb:1IU1|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001025178.1|refseq:NP_001119.3|efo:""Orphanet:528084""|panther:PTHR22780(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E0niV91xZ1PV6Pr6Koq3Xs+9nKg9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:6D1C4EB39C2C0543|rigid:Qk0P9ECHc64htAgBPUelUXOoPbo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WM3	uniprotkb:Q9HCK8	intact:EBI-2811277|uniprotkb:Q6KP05|uniprotkb:Q6HUS3	intact:EBI-1169146|uniprotkb:Q68DQ0|uniprotkb:Q8N3Z9|uniprotkb:Q8NCY4|uniprotkb:Q8TBR9|uniprotkb:Q96F26|uniprotkb:Q4G0D8|uniprotkb:Q6DKH9|uniprotkb:Q6P440|uniprotkb:Q6ZNL7|ensembl:ENSP00000451601.1|ensembl:ENSP00000495070.1|ensembl:ENSP00000495240.1	psi-mi:if2_bacan(display_long)|uniprotkb:infB(gene name)|psi-mi:infB(display_short)|uniprotkb:BA_3950(locus name)|uniprotkb:GBAA_3950(locus name)|uniprotkb:BAS3664(locus name)	psi-mi:chd8_human(display_long)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811283|imex:IM-13779-1519	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR053905|interpro:IPR044145|interpro:IPR006847(Translation initiation factor IF-2, N-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000178(Initiation factor 2)|interpro:IPR023115|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|refseq:WP_000036339.1|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR036925|refseq:NP_846193.1|refseq:YP_029915.1"	"panther:PTHR45623(orthology-group)|dip:DIP-38021N|ensembl:ENSG00000100888.15(gene)|ensembl:ENST00000557364.6(transcript)|ensembl:ENST00000643469.1(transcript)|ensembl:ENST00000646647.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0002039""(p53 binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006397""(mRNA processing)|go:""GO:0007420""(brain development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035176""(social behavior)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042393""(histone binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045945""(positive regulation of transcription by RNA polymerase III)|go:""GO:0048565""(digestive tract development)|go:""GO:0060134""(prepulse inhibition)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071339""(MLL1 complex)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140658""(ATP-dependent chromatin remodeler activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|go:""GO:2000270""(negative regulation of fibroblast apoptotic process)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR034724|interpro:IPR037259|interpro:IPR038718|interpro:IPR049730|interpro:IPR051493|mint:Q9HCK8|rcsb pdb:2CKA|rcsb pdb:2DL6|reactome:R-HSA-3769402|refseq:NP_001164100.1|refseq:NP_065971.2|efo:""Orphanet:261229""|efo:""Orphanet:642675"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:ZybMBb8EpwfT4Z43NREw57NAPPc1392	rogid:QwADLvHNwK00OAboBtAkqaICd489606	intact-crc:ABF2FC9AAEE3C0B4|rigid:e4R/yc+Gb/tBtPO+/7aCggW+Cng	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96JB5	uniprotkb:Q81WE4	intact:EBI-718818|uniprotkb:Q53FA2|uniprotkb:Q9H3F8|uniprotkb:Q9H8G0|uniprotkb:Q9HBR9|uniprotkb:D3DTU1|uniprotkb:D3DTU2|ensembl:ENSP00000344683.4|uniprotkb:B7Z6N4|uniprotkb:F5H3I5	intact:EBI-2811264|uniprotkb:Q6HUJ1|uniprotkb:Q6KNS7	psi-mi:ck5p3_human(display_long)|uniprotkb:CDK5 activator-binding protein C53(gene name synonym)|uniprotkb:Protein HSF-27(gene name synonym)|uniprotkb:CDK5RAP3(gene name)|psi-mi:CDK5RAP3(display_short)|uniprotkb:IC53(gene name synonym)|uniprotkb:MSTP016(orf name)|uniprotkb:OK/SW-cl.114(orf name)|uniprotkb:PP1553(orf name)|uniprotkb:LXXLL/leucine-zipper-containing ARF-binding protein(gene name synonym)|uniprotkb:LZAP(gene name synonym)	psi-mi:syi1_bacan(display_long)|uniprotkb:ileS1(gene name)|psi-mi:ileS1(display_short)|uniprotkb:Isoleucyl-tRNA synthetase 1(gene name synonym)|uniprotkb:BAS3746(locus name)|uniprotkb:BA_4034(locus name)|uniprotkb:GBAA_4034(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811270|imex:IM-13779-1520	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_788276.1|refseq:NP_001265126.1|ensembl:ENSG00000108465.15(gene)|ensembl:ENST00000338399.9(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0001889""(liver development)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0007420""(brain development)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010921""(regulation of phosphatase activity)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030262""(apoptotic nuclear changes)|go:""GO:0030332""(cyclin binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0044818""(mitotic G2/M transition checkpoint)|go:""GO:0045664""(regulation of neuron differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0060318""(definitive erythrocyte differentiation)|go:""GO:0071569""(protein ufmylation)|go:""GO:0071901""(negative regulation of protein serine/threonine kinase activity)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:0140501""(positive regulation of reticulophagy)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1901798""(positive regulation of signal transduction by p53 class mediator)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR008491(Protein of unknown function DUF773)|mint:Q96JB5|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8QFC|refseq:NP_001265127.1|refseq:NP_001265145.1|refseq:NP_001265146.1|refseq:XP_011523599.1|refseq:XP_016880653.1|refseq:XP_016880654.1|panther:PTHR14894(orthology-group)"	"interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR023585|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR050081|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004822""(isoleucine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006428""(isoleucyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|interpro:IPR033708|refseq:WP_000455959.1|refseq:NP_846274.1|refseq:YP_029997.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:K1S/DQ6fYeOm+MiiGicED0chJAw9606	rogid:xstV9KzBf6jt+0sUgWldGrgqqlc1392	intact-crc:40C6B412B8BA366E|rigid:G4rbKool/wq1TQbivTmArOFSJ24	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NX76	uniprotkb:A0A6L8PRN6	intact:EBI-1054315|uniprotkb:Q6IAC4|ensembl:ENSP00000205636.3	intact:EBI-2809795|uniprotkb:Q6KT17|uniprotkb:E9QTD7|uniprotkb:Q81QV1	psi-mi:cklf6_human(display_long)|uniprotkb:Chemokine-like factor superfamily member 6(gene name synonym)|uniprotkb:CMTM6(gene name)|psi-mi:CMTM6(display_short)|uniprotkb:CKLFSF6(gene name synonym)	psi-mi:a0a6l8prn6_bacan(display_long)|uniprotkb:GBAA_2314(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811257|imex:IM-13779-1518	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060271.1|ensembl:ENSG00000091317.8(gene)|ensembl:ENST00000205636.4(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0055038""(recycling endosome membrane)|interpro:IPR008253(Marvel)|interpro:IPR050578|mint:Q9NX76|reactome:R-HSA-6798695|panther:PTHR22776(orthology-group)"	interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR024696|refseq:WP_000249923.1|interpro:IPR051768|interpro:IPR036689	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OrVBhhmdJZSWGfyJc/eYUYNtdYE9606	rogid:F/oxRKTzWTtfjzkNdzflVMqhX0s1392	intact-crc:2483AA13319AEEAB|rigid:FTrUNUS/zovr2m68FnJxBth7rTY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6X8	uniprotkb:A0A6H3AES4	intact:EBI-948566|ensembl:ENSP00000314709.4	intact:EBI-2811324|uniprotkb:Q6HYW1|uniprotkb:Q6KSV8|uniprotkb:E9RCE1|uniprotkb:E9RCE2|uniprotkb:Q81QN9|uniprotkb:A0A0F7RE93	psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym)	psi-mi:a0a6h3aes4_bacan(display_long)|uniprotkb:GBAA_2380(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811329|imex:IM-13779-1526	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055758.1|refseq:XP_005250893.1|refseq:XP_005250894.1|refseq:XP_011515233.1|refseq:XP_011515234.1|ensembl:ENSG00000178764.8(gene)|ensembl:ENST00000314393.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0060040""(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q9Y6X8|rcsb pdb:2DMP|rcsb pdb:3NAU|panther:PTHR15467(orthology-group)"	"interpro:IPR054399|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR023827|interpro:IPR023828|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR050131|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|refseq:WP_000790944.1|interpro:IPR034084|interpro:IPR036852"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606	rogid:GIz9JENfwf7NponUkIqm1coWxy81392	intact-crc:DF93BE81798F5DA1|rigid:Y2tc+VCy8iCDWu3QU+6nr0fC81A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HSZ9	uniprotkb:Q9Y6X8	intact:EBI-2811304|uniprotkb:Q6KXZ4|uniprotkb:Q6I488|uniprotkb:E9R4T3|uniprotkb:E9R4T4|uniprotkb:Q81ZE2|uniprotkb:A0A1V4B8A9	intact:EBI-948566|ensembl:ENSP00000314709.4	psi-mi:a0a6l7hsz9_bacan(display_long)|uniprotkb:gabD(gene name)|psi-mi:gabD(display_short)|uniprotkb:GBAA_0327(locus name)	psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811310|imex:IM-13779-1525	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR010102(Succinic semialdehyde dehydrogenase)|interpro:IPR050740|go:""GO:0004777""(""succinate-semialdehyde dehydrogenase (NAD+) activity"")|go:""GO:0009450""(gamma-aminobutyric acid catabolic process)|refseq:WP_000358103.1|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)"	"refseq:NP_055758.1|refseq:XP_005250893.1|refseq:XP_005250894.1|refseq:XP_011515233.1|refseq:XP_011515234.1|ensembl:ENSG00000178764.8(gene)|ensembl:ENST00000314393.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0060040""(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q9Y6X8|rcsb pdb:2DMP|rcsb pdb:3NAU|panther:PTHR15467(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IKDmk6KMXo8kwWQowTVtLRljgHY1392	rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606	intact-crc:8DEE709F878A1704|rigid:4hXafKS90VqOL/L4Dtd5BMUvUwY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HB35	uniprotkb:O60315	intact:EBI-2810010|uniprotkb:Q6KX90|uniprotkb:Q6I3H7|uniprotkb:E9QTP4|uniprotkb:E9QTP5|uniprotkb:A0A2P0HA09|uniprotkb:Q81V90	intact:EBI-717614|uniprotkb:A0JP09|uniprotkb:Q9UED1|uniprotkb:B7Z2P2|uniprotkb:F5H814|ensembl:ENSP00000386854.2|ensembl:ENSP00000454157.1|ensembl:ENSP00000487174.1	psi-mi:a0a6l7hb35_bacan(display_long)|uniprotkb:aspA1(gene name)|psi-mi:aspA1(display_short)|uniprotkb:GBAA_0609(locus name)	psi-mi:zeb2_human(display_long)|uniprotkb:Zinc finger homeobox protein 1b(gene name synonym)|uniprotkb:Smad-interacting protein 1(gene name synonym)|uniprotkb:ZEB2(gene name)|psi-mi:ZEB2(display_short)|uniprotkb:KIAA0569(gene name synonym)|uniprotkb:SIP1(gene name synonym)|uniprotkb:ZFX1B(gene name synonym)|uniprotkb:HRIHFB2411(orf name)|uniprotkb:ZFHX1B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811336|imex:IM-13779-1524	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004708(Aspartate ammonia-lyase)|interpro:IPR018951|interpro:IPR000362(Fumarate lyase)|interpro:IPR020557|interpro:IPR008948(L-Aspartase-like)|interpro:IPR024083|interpro:IPR022761|interpro:IPR051546|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006531""(aspartate metabolic process)|go:""GO:0008797""(aspartate ammonia-lyase activity)|refseq:WP_000562147.1"	"efo:""Orphanet:261537""|efo:""Orphanet:261552""|ensembl:ENSG00000169554.23(gene)|ensembl:ENST00000409487.7(transcript)|ensembl:ENST00000558170.6(transcript)|ensembl:ENST00000627532.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007399""(nervous system development)|go:""GO:0007417""(central nervous system development)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0019208""(phosphatase regulator activity)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0036446""(myofibroblast differentiation)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0045636""(positive regulation of melanocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048023""(positive regulation of melanin biosynthetic process)|go:""GO:0048066""(developmental pigmentation)|go:""GO:0048143""(astrocyte activation)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0072537""(fibroblast activation)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090649""(response to oxygen-glucose deprivation)|go:""GO:0097324""(melanocyte migration)|go:""GO:1903056""(regulation of melanosome organization)|go:""GO:1904330""(positive regulation of myofibroblast contraction)|go:""GO:1904520""(regulation of myofibroblast cell apoptotic process)|go:""GO:1905603""(regulation of blood-brain barrier permeability)|interpro:IPR001356(Homeobox)|interpro:IPR008598(Drought induced 19)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR051574|mint:O60315|rcsb pdb:2DA7|reactome:R-HSA-9762293|reactome:R-HSA-9823739|reactome:R-HSA-9832991|refseq:NP_001165124.1|refseq:NP_055610.1|refseq:XP_006712944.1|refseq:XP_006712945.1|efo:""Orphanet:626""|panther:PTHR24391(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nnzLQtRPCMiP6XJ4eU50JaPldIo1392	rogid:KIKq943mmyO6wbsDamXsyo0OnEo9606	intact-crc:479B63BA029150A3|rigid:A/8VpgjuLfzoobagdohzjKSAdDM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6X8	uniprotkb:A0A4Y1WE58	intact:EBI-948566|ensembl:ENSP00000314709.4	intact:EBI-2810305|uniprotkb:Q6KW20|uniprotkb:Q6I285|uniprotkb:E9R1F6|uniprotkb:E9R1F7|uniprotkb:A0A2P0HB60|uniprotkb:Q81U00	psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym)	psi-mi:a0a4y1we58_bacan(display_long)|uniprotkb:GBAA_1094(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811317|imex:IM-13779-1523	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055758.1|refseq:XP_005250893.1|refseq:XP_005250894.1|refseq:XP_011515233.1|refseq:XP_011515234.1|ensembl:ENSG00000178764.8(gene)|ensembl:ENST00000314393.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0060040""(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q9Y6X8|rcsb pdb:2DMP|rcsb pdb:3NAU|panther:PTHR15467(orthology-group)"	"interpro:IPR020968|interpro:IPR008979(Galactose-binding like)|interpro:IPR022385|interpro:IPR006530(YD repeat)|interpro:IPR050708|go:""GO:0016020""(membrane)|refseq:WP_000387561.1|interpro:IPR045351|interpro:IPR031325"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606	rogid:8jqYn7kracNCDGYibTeEcZe2fl81392	intact-crc:C0085BBAB4349B80|rigid:FFankUBSnPYsbOBPwBUxSmnfCTo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TED9	uniprotkb:Q81KT8	intact:EBI-1053644|uniprotkb:Q08AN4|uniprotkb:Q08AN5|uniprotkb:Q8IW82|uniprotkb:Q8N8Z5|uniprotkb:Q8N9Q4|ensembl:ENSP00000296721.4	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	psi-mi:af1l1_human(display_long)|uniprotkb:AFAP1L1(gene name)|psi-mi:AFAP1L1(display_short)	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811297|imex:IM-13779-1522	author score:5|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001139809.1|refseq:NP_689619.1|refseq:NP_001309991.1|refseq:NP_001309992.1|ensembl:ENSG00000157510.14(gene)|ensembl:ENST00000296721.9(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0002102""(podosome)|go:""GO:0005829""(cytosol)|go:""GO:0042995""(cell projection)|go:""GO:0070161""(anchoring junction)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030113|panther:PTHR14338(orthology-group)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZQdgj6z1yyjJo/wJZYhAuAYmUDw9606	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	intact-crc:642FAD131B8D0BFD|rigid:qqog0V+SjRb+0HY03jXMbBbiM7I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NQB0	uniprotkb:A0A6L8PRR8	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274.4	intact:EBI-2811394|uniprotkb:Q6I2G7|uniprotkb:Q6KW94|uniprotkb:E9R8J0|uniprotkb:E9R8J1|uniprotkb:Q81U80|uniprotkb:A0A0F7RLC1	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:a0a6l8prr8_bacan(display_long)|uniprotkb:GBAA_1004(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811399|imex:IM-13779-1531	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000148737.18(gene)|ensembl:ENST00000355995.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001568""(blood vessel development)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009749""(response to glucose)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010909""(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016605""(PML body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031016""(pancreas development)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032350""(regulation of hormone metabolic process)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0043570""(maintenance of DNA repeat elements)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045721""(negative regulation of gluconeogenesis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048625""(myoblast fate commitment)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070369""(beta-catenin-TCF7L2 complex)|go:""GO:0071664""(catenin-TCF7L2 complex)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990907""(beta-catenin-TCF complex)|go:""GO:2000675""(negative regulation of type B pancreatic cell apoptotic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430|reactome:R-HSA-9823730|reactome:R-HSA-9825892|refseq:NP_001139746.1|refseq:NP_001139755.1|refseq:NP_001139756.1|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270141.1|refseq:XP_005270146.1|refseq:XP_005270153.1|refseq:XP_005270160.1|refseq:XP_016872081.1|refseq:XP_016872082.1|efo:""Orphanet:528084""|dip:DIP-36236N|ensembl:ENST00000352065.10|ensembl:ENSP00000344823.5|ensembl:ENST00000355717.9|ensembl:ENSP00000347949.4|ensembl:ENSP00000348274.4|ensembl:ENST00000369397.8|ensembl:ENSP00000358404.4|ensembl:ENST00000538897.5|ensembl:ENSP00000446172.1|ensembl:ENST00000627217.3|ensembl:ENSP00000486891.1|panther:PTHR10373(orthology-group)"	"interpro:IPR020843|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR011032(GroES-like)|go:""GO:0016651""(""oxidoreductase activity, acting on NAD(P)H"")|go:""GO:0070402""(NADPH binding)|refseq:WP_000902291.1|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:bJoUAV4WZkl9RHHmLvJxDPIL7Wk1392	intact-crc:05FE7FDD70B98E30|rigid:yt+2z5IcGV6BG4agzezaHbEGIwQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IXZ2	uniprotkb:A0A6L8PDJ5	intact:EBI-2811352|uniprotkb:Q9BUS4|uniprotkb:Q14163|uniprotkb:Q8N4E2|ensembl:ENSP00000262577.5	intact:EBI-2811343|uniprotkb:Q6KSJ7|uniprotkb:Q6HYJ6|uniprotkb:E9R6F8|uniprotkb:E9R6F9|uniprotkb:Q81QB9|uniprotkb:A0A0F7RH87	psi-mi:zc3h3_human(display_long)|uniprotkb:ZC3H3(gene name)|psi-mi:ZC3H3(display_short)|uniprotkb:KIAA0150(gene name synonym)|uniprotkb:ZC3HDC3(gene name synonym)|uniprotkb:SMICL(gene name synonym)|uniprotkb:Smad-interacting CPSF-like factor(gene name synonym)	psi-mi:a0a6l8pdj5_bacan(display_long)|uniprotkb:csbX(gene name)|psi-mi:csbX(display_short)|uniprotkb:GBAA_2510(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811349|imex:IM-13779-1529	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055932.2|ensembl:ENSG00000014164.7(gene)|ensembl:ENST00000262577.6(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005847""(mRNA cleavage and polyadenylation specificity factor complex)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0032927""(positive regulation of activin receptor signaling pathway)|go:""GO:0046872""(metal ion binding)|go:""GO:0051028""(mRNA transport)|go:""GO:0070412""(R-SMAD binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|panther:PTHR46156(orthology-group)"	"interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR050930|refseq:WP_000991764.1|interpro:IPR036259|interpro:IPR004748(Polyol permease)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nDBI6LhiSLHYjLh4Tf6+/PgOrMA9606	rogid:cxQLwi0F0jXAO/aHHdeN7baYuWc1392	intact-crc:CD0E360B7EBCCD95|rigid:sSRmY0mxl0MK0vFZMcVRG4rMz2k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HC63	uniprotkb:Q9UH99	intact:EBI-2811370|uniprotkb:Q6KTZ3|uniprotkb:Q6I014|uniprotkb:E9QYA2|uniprotkb:E9QYA3|uniprotkb:Q81RT7|uniprotkb:A0A0F7RJ72	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|uniprotkb:B0QY62|uniprotkb:Q504T5|ensembl:ENSP00000383992.1|ensembl:ENSP00000385740.1|ensembl:ENSP00000508608.1	psi-mi:a0a6l7hc63_bacan(display_long)|uniprotkb:GBAA_1950(locus name)	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811375|imex:IM-13779-1530	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR018044|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0071555""(cell wall organization)|refseq:WP_000825873.1"	"refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|ensembl:ENSG00000100242.16(gene)|ensembl:ENST00000405510.5(transcript)|ensembl:ENST00000406622.5(transcript)|ensembl:ENST00000689035.1(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0008017""(microtubule binding)|go:""GO:0010008""(endosome membrane)|go:""GO:0021817""(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031022""(nuclear migration along microfilament)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034993""(meiotic nuclear membrane microtubule tethering complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0051642""(centrosome localization)|go:""GO:0090292""(nuclear matrix anchoring at nuclear membrane)|go:""GO:0140444""(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR040994|interpro:IPR045119|mint:Q9UH99|rcsb pdb:3UNP|rcsb pdb:4DXR|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|panther:PTHR12911(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:C+GkPog4qlTLKuFTOFPtKPvk7yQ1392	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	intact-crc:61316C256A0A311B|rigid:nCUx3OFSImOb6GKC/+35YMTGp5o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96RL1	uniprotkb:A0A6L7HG24	intact:EBI-725300|intact:EBI-1263554|uniprotkb:Q5XKQ1|uniprotkb:Q7Z3W7|uniprotkb:Q8N5B9|uniprotkb:Q9BZR1|uniprotkb:Q9BZR5|uniprotkb:Q9UHX7|uniprotkb:A8MSA1|uniprotkb:B3KMZ1|uniprotkb:B4E3N2|ensembl:ENSP00000366434.4|ensembl:ENSP00000421926.1	intact:EBI-2811385|uniprotkb:Q6KMQ6|uniprotkb:Q6HTG4|uniprotkb:E9R169|uniprotkb:E9R170|uniprotkb:Q81M11|uniprotkb:A0A0F7R8D9	psi-mi:uimc1_human(display_long)|uniprotkb:Retinoid X receptor-interacting protein 110(gene name synonym)|uniprotkb:Receptor-associated protein 80(gene name synonym)|uniprotkb:Ubiquitin interaction motif-containing protein 1(gene name synonym)|uniprotkb:UIMC1(gene name)|psi-mi:UIMC1(display_short)|uniprotkb:RAP80(gene name synonym)|uniprotkb:RXRIP110(gene name synonym)	psi-mi:a0a6l7hg24_bacan(display_long)|uniprotkb:GBAA_4444(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811382|imex:IM-13779-1528	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001186226.1|refseq:NP_001186227.1|refseq:NP_057374.3|refseq:XP_005265987.1|refseq:XP_005265993.1|refseq:XP_006714934.1|refseq:NP_001304890.1|refseq:XP_016865063.1|refseq:XP_016865067.1|refseq:XP_016865068.1|dip:DIP-29936N|ensembl:ENSG00000087206.17(gene)|ensembl:ENST00000377227.8(transcript)|ensembl:ENST00000511320.6(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006282""(regulation of DNA repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0010212""(response to ionizing radiation)|go:""GO:0016604""(nuclear body)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042393""(histone binding)|go:""GO:0044818""(mitotic G2/M transition checkpoint)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0061649""(ubiquitin-modified histone reader activity)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0070531""(BRCA1-A complex)|go:""GO:0140861""(DNA repair-dependent chromatin remodeling)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR038868|interpro:IPR040714|mint:Q96RL1|rcsb pdb:2MKF|rcsb pdb:2MKG|rcsb pdb:2N9E|rcsb pdb:2RR9|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|panther:PTHR15932(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR051782|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000891288.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:j5ho+aD4tkX7bXXlROdiprUX1Mc9606	rogid:/pw+ThQWZ4LMdrZ7n9sAVSfc+v41392	intact-crc:4500480CF7CF9093|rigid:q8OdjT9rOZ5QOOvluuvRf98O/x0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H4A3	uniprotkb:A0A0F7REH3	intact:EBI-457907|uniprotkb:O15052|uniprotkb:P54963|uniprotkb:Q86WL5|uniprotkb:Q8N673|uniprotkb:Q9P1S9|uniprotkb:Q4VBX9|intact:EBI-948424|uniprotkb:A1L4B0|uniprotkb:Q6IFS5|uniprotkb:C5HTZ5|uniprotkb:C5HTZ6|uniprotkb:C5HTZ7|uniprotkb:H6WZW3|uniprotkb:Q96CZ6|ensembl:ENSP00000313059.6	intact:EBI-2811064|uniprotkb:Q6KPV8|uniprotkb:E9R093|uniprotkb:Q81YE8	psi-mi:wnk1_human(display_long)|uniprotkb:WNK1(gene name)|psi-mi:WNK1(display_short)|uniprotkb:KDP(gene name synonym)|uniprotkb:KIAA0344(gene name synonym)|uniprotkb:PRKWNK1(gene name synonym)|uniprotkb:Protein kinase with no lysine 1(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 1(gene name synonym)|uniprotkb:Erythrocyte 65 kDa protein(gene name synonym)|uniprotkb:Kinase deficient protein(gene name synonym)|uniprotkb:HSN2(gene name synonym)	psi-mi:a0a0f7reh3_bacan(display_long)|uniprotkb:GBAA_3601(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811363|imex:IM-13779-1527	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:88940""|efo:""Orphanet:970""|ensembl:ENSG00000060237.19(gene)|ensembl:ENST00000315939.11(transcript)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0007165""(signal transduction)|go:""GO:0007507""(heart development)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010766""(negative regulation of sodium ion transport)|go:""GO:0010793""(regulation of mRNA export from nucleus)|go:""GO:0010820""(positive regulation of T cell chemotaxis)|go:""GO:0016020""(membrane)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0030644""(intracellular chloride ion homeostasis)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033633""(negative regulation of cell-cell adhesion mediated by integrin)|go:""GO:0034115""(negative regulation of heterotypic cell-cell adhesion)|go:""GO:0034260""(negative regulation of GTPase activity)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038116""(""chemokine (C-C motif) ligand 21 signaling pathway"")|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048666""(neuron development)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0055075""(potassium ion homeostasis)|go:""GO:0055080""(monoatomic cation homeostasis)|go:""GO:0071474""(cellular hyperosmotic response)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090188""(negative regulation of pancreatic juice secretion)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097022""(lymphocyte migration into lymph node)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1902305""(regulation of sodium ion transmembrane transport)|go:""GO:1903038""(negative regulation of leukocyte cell-cell adhesion)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:1903490""(positive regulation of mitotic cytokinesis)|go:""GO:1904062""(regulation of monoatomic cation transmembrane transport)|go:""GO:1904595""(positive regulation of termination of RNA polymerase II transcription)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990869""(cellular response to chemokine)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|interpro:IPR050588|mint:Q9H4A3|rcsb pdb:4PWN|rcsb pdb:5TF9|rcsb pdb:5WDY|rcsb pdb:5WE8|rcsb pdb:6FBK|reactome:R-HSA-2672351|refseq:NP_001171914.1|refseq:NP_055638.2|refseq:NP_061852.3|refseq:NP_998820.3|refseq:XP_016875326.1|refseq:XP_016875327.1|dip:DIP-32648N|panther:PTHR24361(orthology-group)|ensembl:ENSP00000313059.6|ensembl:ENST00000340908.9|ensembl:ENSP00000341292.5|ensembl:ENST00000530271.6|ensembl:ENSP00000433548.3|ensembl:ENST00000537687.5|ensembl:ENSP00000444465.1|ensembl:ENST00000675631.1|ensembl:ENSP00000502415.1"	refseq:WP_001116379.1|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/06	rogid:Jt4cvhSumyRRIZDmWgj4GsG7wjQ9606	rogid:kRV2TrznOHMKW2jOg5FKoFx9L+41392	intact-crc:A711B92328864164|rigid:GBqYOhseJ7Jl006aVOzpDBPrcH8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81LD0	uniprotkb:Q9NQB0	intact:EBI-2809803|uniprotkb:Q6KM26|uniprotkb:Q6HST3	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274.4	psi-mi:gsa2_bacan(display_long)|uniprotkb:hemL2(gene name)|psi-mi:hemL2(display_short)|uniprotkb:Glutamate-1-semialdehyde aminotransferase 2(gene name synonym)|uniprotkb:BA_4693(locus name)|uniprotkb:GBAA_4693(locus name)|uniprotkb:BAS4358(locus name)	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811406|imex:IM-13779-1532	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004639(Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|rcsb pdb:3K28|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0042286""(glutamate-1-semialdehyde 2,1-aminomutase activity)|refseq:WP_001224513.1|refseq:NP_846906.1|refseq:YP_030605.1|interpro:IPR049704"	"ensembl:ENSG00000148737.18(gene)|ensembl:ENST00000355995.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001568""(blood vessel development)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009749""(response to glucose)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010909""(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016605""(PML body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031016""(pancreas development)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032350""(regulation of hormone metabolic process)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0043570""(maintenance of DNA repeat elements)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045721""(negative regulation of gluconeogenesis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048625""(myoblast fate commitment)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070369""(beta-catenin-TCF7L2 complex)|go:""GO:0071664""(catenin-TCF7L2 complex)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990907""(beta-catenin-TCF complex)|go:""GO:2000675""(negative regulation of type B pancreatic cell apoptotic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430|reactome:R-HSA-9823730|reactome:R-HSA-9825892|refseq:NP_001139746.1|refseq:NP_001139755.1|refseq:NP_001139756.1|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270141.1|refseq:XP_005270146.1|refseq:XP_005270153.1|refseq:XP_005270160.1|refseq:XP_016872081.1|refseq:XP_016872082.1|efo:""Orphanet:528084""|dip:DIP-36236N|ensembl:ENST00000352065.10|ensembl:ENSP00000344823.5|ensembl:ENST00000355717.9|ensembl:ENSP00000347949.4|ensembl:ENSP00000348274.4|ensembl:ENST00000369397.8|ensembl:ENSP00000358404.4|ensembl:ENST00000538897.5|ensembl:ENSP00000446172.1|ensembl:ENST00000627217.3|ensembl:ENSP00000486891.1|panther:PTHR10373(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:GnZPBZpKvZpcwazgpwseq6iVQbg1392	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	intact-crc:059902FD33C4FBED|rigid:PP6JdnEPp0CiD39u/WDyOrvsLmM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UNH7	uniprotkb:A0A6L7HNW1	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	intact:EBI-2811449|uniprotkb:Q6HQL3|uniprotkb:Q6KJY7|uniprotkb:E9QZW1|uniprotkb:E9QZW2|uniprotkb:A0A2P0HLN6|uniprotkb:Q81K14	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	psi-mi:a0a6l7hnw1_bacan(display_long)|uniprotkb:spoIID(gene name)|psi-mi:spoIID(display_short)|uniprotkb:GBAA_5528(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811455|imex:IM-13779-1534	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	"interpro:IPR013486(Sporulation stage II protein D, amidase enhancer LytB)|interpro:IPR013693(Sporulation stage II protein D, amidase enhancer LytB N-terminal)|interpro:IPR014225(Sporulation stage II, protein D firmicutes)|interpro:IPR051922|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0030435""(sporulation resulting in formation of a cellular spore)|rcsb pdb:4RWR|refseq:WP_000672625.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	rogid:1kmpmcWapTSvs/Frk4lApzKieQU1392	intact-crc:76FA7E4AF2B28C07|rigid:nFmgGJ3tj45FgQLzLfHQhU5/Fp8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96R06	uniprotkb:A0A6L8PQC3	intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300.5	intact:EBI-2811440|uniprotkb:Q6I444|uniprotkb:Q6KXV4|uniprotkb:E9QQR3|uniprotkb:E9QQR4|uniprotkb:A0A2P0H9A7|uniprotkb:Q81ZA2	psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym)	psi-mi:a0a6l8pqc3_bacan(display_long)|uniprotkb:GBAA_0370(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811437|imex:IM-13779-1536	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006452.3|panther:PTHR15347(orthology-group)|ensembl:ENSG00000076382.17(gene)|ensembl:ENST00000321765.10(transcript)|go:""GO:0000070""(mitotic sister chromatid segregation)|go:""GO:0000776""(kinetochore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007051""(spindle organization)|go:""GO:0007059""(chromosome segregation)|go:""GO:0008017""(microtubule binding)|go:""GO:0016604""(nuclear body)|go:""GO:0030496""(midbody)|go:""GO:0032388""(positive regulation of intracellular transport)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0035371""(microtubule plus-end)|go:""GO:0036064""(ciliary basal body)|go:""GO:0051294""(establishment of spindle orientation)|go:""GO:0051301""(cell division)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090235""(regulation of metaphase plate congression)|go:""GO:0097431""(mitotic spindle pole)|go:""GO:1905832""(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|refseq:WP_000410216.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606	rogid:+ivfvCodXbxbEMok2GCUbqdVQA01392	intact-crc:640040D80E7646DF|rigid:QvbY25gaiu2RNIFV7v1LeU5n+2c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3ACK0	uniprotkb:O95793	intact:EBI-2811413|uniprotkb:Q6KVF7|uniprotkb:Q6I1K7|uniprotkb:E9QV69|uniprotkb:E9QV70|uniprotkb:Q81TD1|uniprotkb:A0A1Q4M366	intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|uniprotkb:E1P5Y1|uniprotkb:E1P608|ensembl:ENSP00000360922.2|uniprotkb:Q5JW29	psi-mi:a0a6h3ack0_bacan(display_long)|uniprotkb:GBAA_1353(locus name)	psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811418|imex:IM-13779-1535	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011976(Peptidase M3B, oligoendopeptidase-related clade 2)|rcsb pdb:3SKS|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0006518""(peptide metabolic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000008568.1|interpro:IPR045090"	"refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|panther:PTHR46054(orthology-group)|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|ensembl:ENSG00000124214.21(gene)|ensembl:ENST00000371856.7(transcript)|go:""GO:0000512""(lncRNA-mediated post-transcriptional gene silencing)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0007281""(germ cell development)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0030425""(dendrite)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044297""(cell body)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0046726""(positive regulation by virus of viral protein levels in host cell)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098964""(anterograde dendritic transport of messenger ribonucleoprotein complex)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099010""(modification of postsynaptic structure)|go:""GO:1900273""(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|interpro:IPR051740|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY|refseq:XP_005260584.1|refseq:NP_001306063.1|refseq:NP_001306064.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:NhlSbW3/OOXI5SWdBI0YtKRCFNk1392	rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606	intact-crc:264026871C8EE599|rigid:ONi0UYy/Qhih3nUxjtrUXQluBCo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00267	uniprotkb:A0A6L7HPS8	intact:EBI-710464|ensembl:ENSP00000404029.4|ensembl:ENSP00000469090.1|ensembl:ENSP00000470252.1|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639	intact:EBI-2811425|uniprotkb:Q6HRJ4|uniprotkb:Q6KKW0|uniprotkb:E9R632|uniprotkb:E9R633|uniprotkb:A0A2P0HKW8|uniprotkb:Q81XR7	psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym)	psi-mi:a0a6l7hps8_bacan(display_long)|uniprotkb:GBAA_5164(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811430|imex:IM-13779-1533	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000196235.14(gene)|ensembl:ENST00000432763.7(transcript)|ensembl:ENST00000598725.5(transcript)|ensembl:ENST00000599117.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0019899""(enzyme binding)|go:""GO:0032044""(DSIF complex)|go:""GO:0032785""(negative regulation of DNA-templated transcription, elongation)|go:""GO:0032786""(positive regulation of DNA-templated transcription, elongation)|go:""GO:0034243""(regulation of transcription elongation by RNA polymerase II)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0140673""(transcription elongation-coupled chromatin remodeling)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|rcsb pdb:7OKX|rcsb pdb:7OKY|rcsb pdb:7OL0|rcsb pdb:7PKS|rcsb pdb:7UNC|rcsb pdb:7UND|rcsb pdb:7YCX|rcsb pdb:8A3Y|rcsb pdb:8P4C|rcsb pdb:8P4D|rcsb pdb:8P4E|rcsb pdb:8P4F|rcsb pdb:8RBX|rcsb pdb:8UHA|rcsb pdb:8UHD|rcsb pdb:8UHG|rcsb pdb:8UI0|rcsb pdb:8UIS|rcsb pdb:8W8E|rcsb pdb:8W8F|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N|panther:PTHR11125(orthology-group)"	refseq:WP_000535253.1|interpro:IPR036388|interpro:IPR036390	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:8VodOhZyrmNy3xxDTTsB8KugN849606	rogid:86+Q0iLT04LZsjQkZ5F8HfdEIRc1392	intact-crc:D6EBDB9AFC2A1E7B|rigid:VwOR8EKED1O+rPQqegtoBSsW4C0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NQZ2	uniprotkb:A0A6L7HRI8	intact:EBI-714067|uniprotkb:Q6FI82|ensembl:ENSP00000254803.2	intact:EBI-2810366|uniprotkb:Q6F051	psi-mi:sas10_human(display_long)|uniprotkb:CRLZ1(gene name synonym)|uniprotkb:Disrupter of silencing SAS10(gene name synonym)|uniprotkb:UTP3 homolog(gene name synonym)|uniprotkb:Charged amino acid-rich leucine zipper 1(gene name synonym)|uniprotkb:UTP3(gene name)|psi-mi:UTP3(display_short)|uniprotkb:SAS10(gene name synonym)	psi-mi:a0a6l7hri8_bacan(display_long)|uniprotkb:GBAA_pXO2_0034(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811506|imex:IM-13779-1541	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_065101.1|ensembl:ENSG00000132467.4(gene)|ensembl:ENST00000254803.4(transcript)|go:""GO:0000462""(""maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006325""(chromatin organization)|go:""GO:0007420""(brain development)|go:""GO:0032040""(small-subunit processome)|go:""GO:0042274""(ribosomal small subunit biogenesis)|interpro:IPR007146(Small-subunit processome, Utp3)|interpro:IPR018972|mint:Q9NQZ2|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|reactome:R-HSA-6790901|reactome:R-HSA-6791226|panther:PTHR13237(orthology-group)"	"go:""GO:0016020""(membrane)|refseq:WP_000249505.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jfZVDuLFaOgL/g/mUSMktGbsVhQ9606	rogid:CttsAiL8z2LvYlOUlkIGYJ7cxoA1392	intact-crc:E3844FDBAE4ACD5F|rigid:5/9dCoodk96dkn3RO3B+BbAKZHg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NVB0	uniprotkb:O00560	intact:EBI-2811493|uniprotkb:Q6KWL2|uniprotkb:Q6I2T1|uniprotkb:E9R8N8|uniprotkb:E9R8N9|uniprotkb:Q81UK2|uniprotkb:A0A0F7RLK2	intact:EBI-727004|uniprotkb:O43391|uniprotkb:O00173|uniprotkb:Q14CP2|ensembl:ENSP00000260130.4|ensembl:ENSP00000411771.2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:a0a6l8nvb0_bacan(display_long)|uniprotkb:alsS(gene name)|psi-mi:alsS(display_short)|uniprotkb:GBAA_0866(locus name)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811499|imex:IM-13779-1538	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012782(Acetolactate synthase, catabolic)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR029035|interpro:IPR029061|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003984""(acetolactate synthase activity)|go:""GO:0005948""(acetolactate synthase complex)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0034077""(butanediol metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_000103511.1|interpro:IPR045229"	"ensembl:ENSG00000137575.12(gene)|ensembl:ENST00000260130.9(transcript)|ensembl:ENST00000413219.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0005109""(frizzled binding)|go:""GO:0005137""(interleukin-5 receptor binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005895""(interleukin-5 receptor complex)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016020""(membrane)|go:""GO:0019838""(growth factor binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042043""(neurexin family protein binding)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045545""(syndecan binding)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0098793""(presynapse)|go:""GO:0099054""(presynapse assembly)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051230|mint:O00560|rcsb pdb:1N99|rcsb pdb:1NTE|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|rcsb pdb:7FSG|rcsb pdb:7FSH|rcsb pdb:7FSI|rcsb pdb:7FSJ|rcsb pdb:7FSK|rcsb pdb:7FSL|rcsb pdb:7FT5|rcsb pdb:7FSM|rcsb pdb:7FSN|rcsb pdb:7FSO|rcsb pdb:7FSP|rcsb pdb:7FSQ|rcsb pdb:7FSR|rcsb pdb:7FSS|rcsb pdb:7FST|rcsb pdb:7FSU|rcsb pdb:7FSV|rcsb pdb:7FSW|rcsb pdb:7FSX|rcsb pdb:7FSY|rcsb pdb:7FSZ|rcsb pdb:7FT0|rcsb pdb:7FT1|rcsb pdb:7FT2|rcsb pdb:7FT3|rcsb pdb:7FT4|rcsb pdb:7FT6|rcsb pdb:7FT7|rcsb pdb:7FT8|rcsb pdb:7FT9|rcsb pdb:7FTA|rcsb pdb:7FTB|rcsb pdb:7FTC|rcsb pdb:7FTD|rcsb pdb:8AAI|rcsb pdb:8AAK|rcsb pdb:8AAO|rcsb pdb:8AAP|rcsb pdb:8BLU|rcsb pdb:8BLV|rcsb pdb:8HCK|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-6798695|refseq:NP_001007068.1|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|dip:DIP-42705N|panther:PTHR12345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:rRCMmJc9HuwjVl3UsPYv6jvntSI1392	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	intact-crc:CB5A3316774E3EB4|rigid:wMU52hAL/qV3TgcE5qE2DcjbwYc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14242	uniprotkb:A0A6L8PBA4	intact:EBI-1030190|uniprotkb:Q12775|uniprotkb:Q6GTW7|uniprotkb:Q8N7J7|uniprotkb:B4DQC3|uniprotkb:A8K2Y0|uniprotkb:B7Z5C7|uniprotkb:J3KMX6|ensembl:ENSP00000447752.1	intact:EBI-2811481|uniprotkb:Q6HWM6|uniprotkb:Q6KQR8|uniprotkb:E9R9K3|uniprotkb:E9R9K4|uniprotkb:Q81NG1|uniprotkb:A0A0F7RFB0	psi-mi:selpl_human(display_long)|uniprotkb:SELPLG(gene name)|psi-mi:SELPLG(display_short)|uniprotkb:Selectin P ligand(gene name synonym)	psi-mi:a0a6l8pba4_bacan(display_long)|uniprotkb:GBAA_3236(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811486|imex:IM-13779-1540	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193538.1|refseq:NP_002997.2|dip:DIP-37668N|ensembl:ENSG00000110876.11(gene)|ensembl:ENST00000550948.2(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001931""(uropod)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0050900""(leukocyte migration)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0050902""(leukocyte adhesive activation)|go:""GO:0071354""(cellular response to interleukin-6)|interpro:IPR026195|rcsb pdb:1G1S|reactome:R-HSA-202733|panther:PTHR17384(orthology-group)"	"interpro:IPR027278|interpro:IPR005966(Pyridoxal phosphate-dependent deaminase)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|go:""GO:0019148""(D-cysteine desulfhydrase activity)|refseq:WP_001046577.1|interpro:IPR036052"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9UTaluLRA9WEeiqsCXJMkKOmbhc9606	rogid:wppwoIBS9yJ6YJCkewhEheENTIg1392	intact-crc:B64DF9FF3C0BAEF1|rigid:dzvOsE2fjO2ufUGGNZ+umAbw3qE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3P1TQ19	uniprotkb:Q9UQE7	intact:EBI-2811472|uniprotkb:A0A0J1HLL8|uniprotkb:Q6I4W3|uniprotkb:Q6KYK7|uniprotkb:E9QSZ3|uniprotkb:E9QSZ4|uniprotkb:Q81VV9|uniprotkb:A0A2A8KMR5	intact:EBI-80718|uniprotkb:O60464|uniprotkb:Q5T482|ensembl:ENSP00000354720.5|uniprotkb:A8K156	psi-mi:a0a3p1tq19_bacan(display_long)|uniprotkb:GBAA_0080(locus name)	psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811469|imex:IM-13779-1537	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR050130|interpro:IPR027417|interpro:IPR028299|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034605""(cellular response to heat)|refseq:WP_000971179.1|interpro:IPR036628|interpro:IPR041546"	"ensembl:ENSG00000108055.11(gene)|ensembl:ENST00000361804.5(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000785""(chromatin)|go:""GO:0000800""(lateral element)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003777""(microtubule motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005829""(cytosol)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0008278""(cohesin complex)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0030892""(mitotic cohesin complex)|go:""GO:0030893""(meiotic cohesin complex)|go:""GO:0034087""(establishment of mitotic sister chromatid cohesion)|go:""GO:0034089""(establishment of meiotic sister chromatid cohesion)|go:""GO:0036033""(mediator complex binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0051301""(cell division)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0070840""(dynein complex binding)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0097431""(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|rcsb pdb:7W1M|rcsb pdb:8P0A|rcsb pdb:8ROH|rcsb pdb:8ROI|rcsb pdb:8ROJ|rcsb pdb:8ROK|rcsb pdb:8ROL|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_005436.1|panther:PTHR43977(orthology-group)|efo:""Orphanet:199""|dip:DIP-29200N|ensembl:ENSP00000354720.5"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/12	rogid:0gBmMjDFwwFXk8GpRSENJnWyTiI1392	rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606	intact-crc:6ABA6F75EB094BCD|rigid:Wc61xUs4D0KGfqPgepzZ/c5xTfw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:O95721	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-490676|ensembl:ENSP00000215730.6	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:snp29_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-29(gene name synonym)|uniprotkb:Soluble 29 kDa NSF attachment protein(gene name synonym)|uniprotkb:SNAP29(gene name)|psi-mi:SNAP29(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811462|imex:IM-13779-1539	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"ensembl:ENSG00000099940.12(gene)|ensembl:ENST00000215730.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005776""(autophagosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006903""(vesicle targeting)|go:""GO:0015031""(protein transport)|go:""GO:0016082""(synaptic vesicle priming)|go:""GO:0016240""(autophagosome membrane docking)|go:""GO:0019905""(syntaxin binding)|go:""GO:0020018""(ciliary pocket membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031629""(synaptic vesicle fusion to presynaptic active zone membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0060271""(cilium assembly)|go:""GO:0061025""(membrane fusion)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098793""(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|mint:O95721|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-6798695|reactome:R-HSA-6811438|refseq:NP_004773.1|efo:""Orphanet:66631""|dip:DIP-56475N|panther:PTHR19305(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:4HyjERPnEDdBgiGt70N9oyrMN1k9606	intact-crc:56D69CE0174F5D12|rigid:fvePjJ3eruYLqB7nNYiA/q+SHuQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UK73	uniprotkb:A0A6L7HQR3	intact:EBI-310482|uniprotkb:O43146|ensembl:ENSP00000307298.4	intact:EBI-2811526|uniprotkb:Q6HQ63|uniprotkb:Q6KJK4|uniprotkb:E9R1X9|uniprotkb:E9R1Y0|uniprotkb:Q81JM0|uniprotkb:A0A1Q4LWI1	psi-mi:fem1b_human(display_long)|uniprotkb:FEM1B(gene name)|psi-mi:FEM1B(display_short)|uniprotkb:KIAA0396(gene name synonym)|uniprotkb:F1AA(gene name synonym)|uniprotkb:FEM1-beta(gene name synonym)|uniprotkb:Fem-1-like death receptor-binding protein alpha(gene name synonym)|uniprotkb:Fem-1-like in apoptotic pathway protein alpha(gene name synonym)	psi-mi:a0a6l7hqr3_bacan(display_long)|uniprotkb:GBAA_5684(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811531|imex:IM-13779-1544	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056137.1|ensembl:ENSG00000169018.6(gene)|ensembl:ENST00000306917.5(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0005123""(death receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051438""(regulation of ubiquitin-protein transferase activity)|go:""GO:0060442""(branching involved in prostate gland morphogenesis)|go:""GO:0060743""(epithelial cell maturation involved in prostate gland development)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000001""(regulation of DNA damage checkpoint)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:Q9UK73|rcsb pdb:6LBF|rcsb pdb:7CNG|rcsb pdb:7EL6|rcsb pdb:8IJ1|rcsb pdb:8JE1|rcsb pdb:8JE2|rcsb pdb:8WQA|rcsb pdb:8WQB|rcsb pdb:8WQC|rcsb pdb:8WQD|rcsb pdb:8WQE|rcsb pdb:8WQF|rcsb pdb:8WQG|rcsb pdb:8WQH|rcsb pdb:8WQI|reactome:R-HSA-8951664|dip:DIP-31663N|panther:PTHR24173(orthology-group)"	"interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR050256|interpro:IPR029044|go:""GO:0005886""(plasma membrane)|go:""GO:0016757""(glycosyltransferase activity)|refseq:WP_001170714.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:ODOxw01NrJ8fUJv2XopsdTYtAr49606	rogid:FZF33SfiwULL1x5+MFR5rJPn+yo1392	intact-crc:F06C9B89DBDF065B|rigid:tqjnsJ7APWlkFx5Z35MtImla8r4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VM2	uniprotkb:Q15276	intact:EBI-2811516|uniprotkb:Q6I4L9|uniprotkb:Q6KYC1	intact:EBI-447043|uniprotkb:O95369|uniprotkb:Q8IVX3|uniprotkb:B2RAG7|ensembl:ENSP00000445408.2	psi-mi:metn1_bacan(display_long)|uniprotkb:metN1(gene name)|psi-mi:metN1(display_short)|uniprotkb:BA_0174(locus name)|uniprotkb:GBAA_0174(locus name)|uniprotkb:BAS0176(locus name)	psi-mi:rabe1_human(display_long)|uniprotkb:Rabaptin-5(gene name synonym)|uniprotkb:Rabaptin-5alpha(gene name synonym)|uniprotkb:Rabaptin-4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-17(gene name synonym)|uniprotkb:RABEP1(gene name)|psi-mi:RABEP1(display_short)|uniprotkb:RABPT5(gene name synonym)|uniprotkb:RABPT5A(gene name synonym)|uniprotkb:RAB5EP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811513|imex:IM-13779-1542	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR018449|interpro:IPR050086|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0033232""(ABC-type D-methionine transporter activity)|refseq:WP_000571358.1|interpro:IPR041701|interpro:IPR045865|refseq:NP_842738.1|refseq:YP_026461.1"	"refseq:NP_001278510.1|refseq:NP_001077054.1|refseq:NP_004694.2|dip:DIP-29350N|rcsb pdb:1TU3|ensembl:ENSG00000029725.17(gene)|ensembl:ENST00000537505.6(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006915""(apoptotic process)|go:""GO:0008083""(growth factor activity)|go:""GO:0015031""(protein transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055037""(recycling endosome)|go:""GO:0061025""(membrane fusion)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1903441""(protein localization to ciliary membrane)|interpro:IPR003914(Rabaptin)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR018514|mint:Q15276|rcsb pdb:1P4U|rcsb pdb:1X79|rcsb pdb:4N3Y|rcsb pdb:4N3Z|rcsb pdb:4Q9U|reactome:R-HSA-8854214|panther:PTHR31179(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:qQq+wPOZbbw8RNRWcF8CIv2GE2U1392	rogid:FDHgN8w6jbAPC3iQfeLY6sdLkrs9606	intact-crc:49029FEE0D9AC9C6|rigid:0iZEwH2kzkrDaAoEsVEAlWmQ7HY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:Q9H799	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-2811541|uniprotkb:Q9H5T1|uniprotkb:Q8N8L4|uniprotkb:Q4G174|uniprotkb:Q9H8T9|intact:EBI-3261532|uniprotkb:A8MUB7|uniprotkb:B7ZLV7|uniprotkb:Q6DK46|ensembl:ENSP00000421690.1	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:cpln1_human(display_long)|uniprotkb:C5orf42(gene name synonym)|uniprotkb:JBTS17(gene name synonym)|uniprotkb:Protein JBTS17(gene name synonym)|uniprotkb:CPLANE1(gene name)|psi-mi:CPLANE1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811538|imex:IM-13779-1543	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"ensembl:ENSG00000197603.16(gene)|ensembl:ENST00000508244.5(transcript)|go:""GO:0016020""(membrane)|go:""GO:0035869""(ciliary transition zone)|go:""GO:0060271""(cilium assembly)|interpro:IPR028236|interpro:IPR036322|mint:Q9H799|refseq:NP_075561.3|efo:""Orphanet:2754""|efo:""Orphanet:475""|efo:""Orphanet:65684""|panther:PTHR14492(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:8zhawWxiqpQM34EraNekNaz/N/o9606	intact-crc:C45E933DD01E319A|rigid:ZTSKsiiE2Gp7ptDb904IC0p5iYQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3P1TYG2	uniprotkb:Q8NDN9	intact:EBI-2811562|uniprotkb:Q6KW66|uniprotkb:Q6I2D9|uniprotkb:E9QVT7|uniprotkb:E9QVT8|uniprotkb:Q81U51|uniprotkb:A0A0J1KUD1	intact:EBI-2811558|ensembl:ENSP00000258646.3|ensembl:ENSP00000367552.2|uniprotkb:Q969U9|intact:EBI-3044072|uniprotkb:Q8IY29	psi-mi:a0a3p1tyg2_bacan(display_long)|uniprotkb:GBAA_1035(locus name)	psi-mi:rcbt1_human(display_long)|uniprotkb:RCBTB1(gene name)|psi-mi:RCBTB1(display_short)|uniprotkb:CLLD7(gene name synonym)|uniprotkb:E4.5(gene name synonym)|uniprotkb:Chronic lymphocytic leukemia deletion region gene 7 protein(gene name synonym)|uniprotkb:Regulator of chromosome condensation and BTB domain-containing protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811555|imex:IM-13779-1545	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000835(Bacterial regulatory protein, MarR)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|refseq:WP_000841455.1|interpro:IPR036388|interpro:IPR036390"	"ensembl:ENSG00000136144.12(gene)|ensembl:ENST00000258646.3(transcript)|ensembl:ENST00000378302.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006325""(chromatin organization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR047996|interpro:IPR051625|mint:Q8NDN9|refseq:NP_060661.3|refseq:XP_005266498.1|refseq:XP_011533435.1|refseq:XP_011533436.1|efo:""Orphanet:99002""|panther:PTHR22870(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Glc5tFpthPAr8yk9CzLz+0N3qmQ1392	rogid:qlFRfKV0PffERWU2HnbL6M64qa09606	intact-crc:77B04BAF35CC156A|rigid:+XFUqekidP3rAEyBocBzKBWPMJQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3ADD1	uniprotkb:P55786	intact:EBI-2811613|uniprotkb:Q6HRK5|uniprotkb:Q6KKX0|uniprotkb:E9QZD5|uniprotkb:E9QZD6|uniprotkb:Q81XS7|uniprotkb:A0A1S0QRP5	intact:EBI-1046129|uniprotkb:Q6P145|uniprotkb:Q9NP16|uniprotkb:Q9UEM2|uniprotkb:B7Z463|ensembl:ENSP00000320324.4|ensembl:ENSP00000503682.1	psi-mi:a0a6h3add1_bacan(display_long)|uniprotkb:Alpha-phosphoglucomutase(gene name synonym)|uniprotkb:Glucose phosphomutase(gene name synonym)|uniprotkb:GBAA_5153(locus name)	psi-mi:psa_human(display_long)|uniprotkb:NPEPPS(gene name)|psi-mi:NPEPPS(display_short)|uniprotkb:PSA(gene name synonym)|uniprotkb:Cytosol alanyl aminopeptidase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811610|imex:IM-13779-1549	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006166""(purine ribonucleoside salvage)|go:""GO:0008973""(phosphopentomutase activity)|refseq:WP_001104191.1|interpro:IPR036900"	"refseq:NP_006301.3|refseq:NP_001317186.1|ensembl:ENSG00000141279.18(gene)|ensembl:ENST00000322157.9(transcript)|ensembl:ENST00000677120.1(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0042277""(peptide binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|interpro:IPR045357|interpro:IPR050344|mint:P55786|rcsb pdb:8SW0|rcsb pdb:8SW1|reactome:R-HSA-983168|panther:PTHR11533(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:35B45uRyKPVI0bM8btRq2zn0YUQ1392	rogid:gDl9SPlJhCOhA8uF4OEw+lIPh2M9606	intact-crc:412D32D04C71FB97|rigid:pJ0XlTFDRnpa0EOWmQvKtJevI7Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-1033611	uniprotkb:A0A6L8P3I2	-	intact:EBI-2811571|uniprotkb:A0A1Q4M2S2|uniprotkb:Q6I206|uniprotkb:Q6KVU4|uniprotkb:E9RAG4|uniprotkb:E9RAG5|uniprotkb:Q81TS3|uniprotkb:A0A2A7DD91	psi-mi:q7z5w1_human(display_short)|psi-mi:EBI-1033611(display_long)|uniprotkb:IGHV4-31(gene name)|psi-mi:IGHV4-31(display_short)	psi-mi:a0a6l8p3i2_bacan(display_long)|uniprotkb:GBAA_1192(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811576|imex:IM-13779-1546	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q7Z5W1(uniprot-removed-ac)	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|refseq:WP_000534165.1|interpro:IPR035906|interpro:IPR045621"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCK2M2OlKlXGmi32G7i6d1bC/V09606	rogid:SXL75EkM2v0JzmCCHwl3FIhC4W81392	intact-crc:BECC594ADEFE0EDC|rigid:bXnsN5c5zCqXU5seJiauuTjPKeY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BVL2	uniprotkb:A0A6L8PKS7	intact:EBI-2811583|uniprotkb:O43160|uniprotkb:Q5JRG5|uniprotkb:Q5JRG2|uniprotkb:A6NI12|uniprotkb:B4DZJ1|ensembl:ENSP00000371155.3	intact:EBI-2809705|uniprotkb:Q6HR58|uniprotkb:Q6KKH5|uniprotkb:E9QWF2|uniprotkb:E9QWF3|uniprotkb:A0A2P0HL14|uniprotkb:Q81XC3	psi-mi:nup58_human(display_long)|uniprotkb:NUP58(gene name)|psi-mi:NUP58(display_short)|uniprotkb:58 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0410(gene name synonym)|uniprotkb:NUPL1(gene name synonym)|uniprotkb:Nucleoporin-like protein 1(gene name synonym)	psi-mi:a0a6l8pks7_bacan(display_long)|uniprotkb:GBAA_5317(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811590|imex:IM-13779-1548	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001008564.1|refseq:NP_054808.1|ensembl:ENSG00000139496.18(gene)|ensembl:ENST00000381736.8(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0015031""(protein transport)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042306""(regulation of protein import into nucleus)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0051028""(mRNA transport)|interpro:IPR024882|mint:Q9BVL2|rcsb pdb:4JO7|rcsb pdb:4JO9|rcsb pdb:4JQ5|rcsb pdb:5IJN|rcsb pdb:5IJO|rcsb pdb:7PER|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9705671|panther:PTHR13437(orthology-group)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR051310|interpro:IPR025278|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|refseq:WP_000455036.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:r5XY6QyOFxuZgJjeuVPoLag3YNI9606	rogid:LEAQuRzrOsJwYgZq7QXDmoKrfqM1392	intact-crc:B01579F88C00B0C9|rigid:ZkwjjwwOOAsCoqxZNVpJN7M8fmk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NYI0	uniprotkb:A0A6L7H165	intact:EBI-2798394|uniprotkb:A6NFQ4|uniprotkb:Q6B003|uniprotkb:Q9Y2F1|uniprotkb:E9KL50|intact:EBI-28988041	intact:EBI-2811597|uniprotkb:Q6KPI1|uniprotkb:Q6HVB3|uniprotkb:E9QV35|uniprotkb:E9QV36|uniprotkb:A0A2P0HHN5|uniprotkb:Q81Y15	psi-mi:psd3_human(display_long)|uniprotkb:EFA6D(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D(gene name synonym)|uniprotkb:EFA6R(gene name synonym)|uniprotkb:HCA67(gene name synonym)|uniprotkb:KIAA0942(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 67(gene name synonym)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 3(gene name synonym)|uniprotkb:PSD3(gene name)|psi-mi:PSD3(display_short)|uniprotkb:Epididymis tissue protein Li 20mP(gene name synonym)	psi-mi:a0a6l7h165_bacan(display_long)|uniprotkb:GBAA_3744(locus name)|uniprotkb:tkt2(gene name)|psi-mi:tkt2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811603|imex:IM-13779-1547	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056125.3|refseq:NP_996792.1|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:Q9NYI0|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0014069""(postsynaptic density)|go:""GO:0032012""(regulation of ARF protein signal transduction)|go:""GO:0032587""(ruffle membrane)|panther:PTHR10663(orthology-group)"	"interpro:IPR033247|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|rcsb pdb:3M49|interpro:IPR029061|go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|refseq:WP_000019755.1|rcsb pdb:3HYL|interpro:IPR049557"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wu9g5GmiJva6VGDtz8duECqvI3w9606	rogid:/3w4Fmuo2N06ZcrbsjphHSbI8do1392	intact-crc:56107B5F93301B7D|rigid:9+r1ClAe9vvgr0yW2mLsGtZEt7w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P2X1	uniprotkb:O00151	intact:EBI-2811664|uniprotkb:Q6HWH8|uniprotkb:Q6KQM9|uniprotkb:E9QRE5|uniprotkb:E9QRE6|uniprotkb:Q81NC2|uniprotkb:A0A0F7R9W0	intact:EBI-724897|uniprotkb:Q5VZH5|uniprotkb:Q9BPZ9|uniprotkb:B2RBS6|ensembl:ENSP00000360305.3	psi-mi:a0a6l8p2x1_bacan(display_long)|uniprotkb:GBAA_3288(locus name)	psi-mi:pdli1_human(display_long)|uniprotkb:Elfin(gene name synonym)|uniprotkb:LIM domain protein CLP-36(gene name synonym)|uniprotkb:C-terminal LIM domain protein 1(gene name synonym)|uniprotkb:PDLIM1(gene name)|psi-mi:PDLIM1(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:CLP36(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811661|imex:IM-13779-1552	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR043502|interpro:IPR017961|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR043128|interpro:IPR024728|interpro:IPR050116|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0009432""(SOS response)|go:""GO:0042276""(error-prone translesion synthesis)|refseq:WP_000272549.1|interpro:IPR036775"	"refseq:NP_066272.1|ensembl:ENSG00000107438.9(gene)|ensembl:ENST00000329399.7(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001725""(stress fiber)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003779""(actin binding)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007507""(heart development)|go:""GO:0010761""(fibroblast migration)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030950""(establishment or maintenance of actin cytoskeleton polarity)|go:""GO:0031941""(filamentous actin)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0051371""(muscle alpha-actinin binding)|go:""GO:0061061""(muscle structure development)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR028537|interpro:IPR031847|interpro:IPR036034|interpro:IPR050604|mint:O00151|rcsb pdb:1X62|rcsb pdb:2PKT|panther:PTHR24214(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fUIT+VEfXS3bjWD3plCkaA/yspE1392	rogid:kUUqX2NgmaXbdbESj6oHxE+EQ2g9606	intact-crc:666A9C7CB8025EB7|rigid:NcXlW75Cc244BRvfFMRPGRInnMY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PCN9	uniprotkb:P36873	intact:EBI-2811622|uniprotkb:Q6KV21|uniprotkb:Q6I170|uniprotkb:E9QUA2|uniprotkb:E9QUA3|uniprotkb:A0A2P0HBZ9|uniprotkb:Q81SZ0	intact:EBI-356283|ensembl:ENSP00000335084.5	psi-mi:a0a6l8pcn9_bacan(display_long)|uniprotkb:fer(gene name)|psi-mi:fer(display_short)|uniprotkb:GBAA_1503(locus name)	psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811628|imex:IM-13779-1550	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001080(3Fe-4S ferredoxin)|interpro:IPR017896|interpro:IPR052395|go:""GO:0005506""(iron ion binding)|go:""GO:0009055""(electron transfer activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_001151993.1"	"refseq:NP_001231903.1|refseq:NP_002701.1|panther:PTHR11668(orthology-group)|ensembl:ENSG00000186298.12(gene)|ensembl:ENST00000335007.10(transcript)|go:""GO:0000070""(mitotic sister chromatid segregation)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000776""(kinetochore)|go:""GO:0001824""(blastocyst development)|go:""GO:0003723""(RNA binding)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0005977""(glycogen metabolic process)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0016607""(nuclear speck)|go:""GO:0016791""(phosphatase activity)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030496""(midbody)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043153""(entrainment of circadian clock by photoperiod)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046822""(regulation of nucleocytoplasmic transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186(""Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase"")|interpro:IPR029052|interpro:IPR031675|interpro:IPR050341|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|rcsb pdb:5INB|rcsb pdb:5J28|rcsb pdb:7SD0|rcsb pdb:8B5R|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-9726840|reactome:R-HSA-9726842|reactome:R-HSA-9828806|dip:DIP-749N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Aok6PtI5iwR7os10dk6r1mb+PTs1392	rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606	intact-crc:01D316943BA34BC3|rigid:55vFqRrrLRlS5+oUuuszKjTsHSM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P78364	uniprotkb:A0A6L7H1G2	intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659.1|ensembl:ENSP00000440674.1	intact:EBI-2809927	psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym)	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811654|imex:IM-13779-1554	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2512""|dip:DIP-44567N|ensembl:ENSG00000111752.11(gene)|ensembl:ENST00000543824.5(transcript)|ensembl:ENST00000544916.6(transcript)|go:""GO:0001739""(sex chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016604""(nuclear body)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0042393""(histone binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|interpro:IPR050548|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|refseq:NP_004417.2|panther:PTHR12247(orthology-group)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/28	rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	intact-crc:B98AD79A6EA2E983|rigid:0S3PMxzrKj/L82F23jWQkf1rMto	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PQR4	uniprotkb:O15162	intact:EBI-2811635|uniprotkb:Q6I443|uniprotkb:Q6KXV3|uniprotkb:E9R6Y1|uniprotkb:E9R6Y2|uniprotkb:Q81ZA1|uniprotkb:A0A2B6CBL2	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	psi-mi:a0a6l8pqr4_bacan(display_long)|uniprotkb:GBAA_0371(locus name)	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811640|imex:IM-13779-1553	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR032091|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|go:""GO:0004556""(alpha-amylase activity)|go:""GO:0009313""(oligosaccharide catabolic process)|refseq:WP_001044735.1|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR045857"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Dtzg5gPp1dA60+U3XNlVLtv3qQ01392	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	intact-crc:6A1B736B99AAD75A|rigid:CWq7hOPe1drukmbf6t5t5+421Mc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81X77	uniprotkb:Q16512	intact:EBI-2810439|uniprotkb:Q6HR13|uniprotkb:Q6KKD2	intact:EBI-602382|intact:EBI-1384186|intact:EBI-748186|uniprotkb:A8K7W5|uniprotkb:B2R9R4|uniprotkb:B3KVN3|uniprotkb:Q504U4|uniprotkb:Q8IUV5|uniprotkb:Q9UD44|uniprotkb:Q15143|ensembl:ENSP00000242783.7	psi-mi:gpmi_bacan(display_long)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)|uniprotkb:gpmA(gene name synonym)|uniprotkb:BA_5365(locus name)|uniprotkb:GBAA_5365(locus name)|uniprotkb:BAS4986(locus name)	psi-mi:pkn1_human(display_long)|uniprotkb:PKN1(gene name)|psi-mi:PKN1(display_short)|uniprotkb:PKN(gene name synonym)|uniprotkb:PRK1(gene name synonym)|uniprotkb:PRKCL1(gene name synonym)|uniprotkb:PAK1(gene name synonym)|uniprotkb:Protease-activated kinase 1(gene name synonym)|uniprotkb:Protein kinase C-like 1(gene name synonym)|uniprotkb:Protein kinase C-like PKN(gene name synonym)|uniprotkb:Protein kinase PKN-alpha(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 1(gene name synonym)|uniprotkb:Serine-threonine protein kinase N(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811647|imex:IM-13779-1551	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|rcsb pdb:2IFY|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030435""(sporulation resulting in formation of a cellular spore)|go:""GO:0043937""(regulation of sporulation)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|refseq:WP_001231153.1|interpro:IPR036646|refseq:NP_847539.1|refseq:YP_031225.1"	"refseq:NP_002732.3|refseq:NP_998725.1|dip:DIP-34240N|ensembl:ENSG00000123143.13(gene)|ensembl:ENST00000242783.11(transcript)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001783""(B cell apoptotic process)|go:""GO:0002634""(regulation of germinal center formation)|go:""GO:0002637""(regulation of immunoglobulin production)|go:""GO:0003014""(renal system process)|go:""GO:0003682""(chromatin binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004697""(diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004698""(calcium,diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004699""(diacylglycerol-dependent, calcium-independent serine/threonine kinase activity)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006972""(hyperosmotic response)|go:""GO:0007165""(signal transduction)|go:""GO:0010631""(epithelial cell migration)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030496""(midbody)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042393""(histone binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0048536""(spleen development)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0060765""(regulation of androgen receptor signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037317|interpro:IPR037784|mint:Q16512|rcsb pdb:1CXZ|rcsb pdb:1URF|rcsb pdb:2RMK|rcsb pdb:4NKG|rcsb pdb:4OTD|rcsb pdb:4OTG|rcsb pdb:4OTH|rcsb pdb:4OTI|reactome:R-HSA-5625740|reactome:R-HSA-5625886|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|panther:PTHR24356(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:pxX2Dycc6/EBhmFHPZ5uVcHE6I41392	rogid:4g0klnFDUlztO05MH9R4sECDTtU9606	intact-crc:7465BF6DC0F62203|rigid:hby8KI/dJM2TccMn8e0zg30gLN8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PZQ9	uniprotkb:Q6ZW49	intact:EBI-2811687|uniprotkb:Q6KQL0|uniprotkb:Q6HWG2|uniprotkb:E9QX97|uniprotkb:E9QX98|uniprotkb:Q81NA3|uniprotkb:A0A0F7RF52	intact:EBI-743225|uniprotkb:O15404|uniprotkb:Q6N099|uniprotkb:Q6ZWH9|uniprotkb:Q7Z315|uniprotkb:Q86UN0|uniprotkb:Q8N4P9|uniprotkb:Q96HP2|ensembl:ENSP00000384048.1	psi-mi:a0a6l8pzq9_bacan(display_long)|uniprotkb:GBAA_3312(locus name)|uniprotkb:DABA aminotransferase(gene name synonym)	psi-mi:paxi1_human(display_long)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym)|uniprotkb:PAXIP1(gene name)|psi-mi:PAXIP1(display_short)|uniprotkb:PAXIP1L(gene name synonym)|uniprotkb:PTIP(gene name synonym)|uniprotkb:CAGF28(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811684|imex:IM-13779-1555	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005814(Aminotransferase class-III)|interpro:IPR004637(Diaminobutyrate-2-oxoglutarate transaminase)|interpro:IPR012773(Diaminobutyrate--2-oxoglutarate aminotransferase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0019491""(ectoine biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0045303""(diaminobutyrate-2-oxoglutarate transaminase activity)|go:""GO:0047307""(diaminobutyrate-pyruvate transaminase activity)|refseq:WP_000261660.1|interpro:IPR049704"	"refseq:NP_031375.3|refseq:XP_005249596.1|refseq:XP_016867370.1|dip:DIP-41786N|ensembl:ENSG00000157212.20(gene)|ensembl:ENST00000404141.6(transcript)|go:""GO:0001570""(vasculogenesis)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0010212""(response to ionizing radiation)|go:""GO:0016363""(nuclear matrix)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0048304""(positive regulation of isotype switching to IgG isotypes)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0060612""(adipose tissue development)|go:""GO:0060717""(chorion development)|go:""GO:1902749""(regulation of cell cycle G2/M phase transition)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR051579|mint:Q6ZW49|rcsb pdb:3SQD|reactome:R-HSA-5617472|reactome:R-HSA-5693571|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922|panther:PTHR23196(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1pSxtgDf4BoJ9dx3Bl92b9g3Pug1392	rogid:djzoPtMxXMP9LBvpzVNBcq04QEY9606	intact-crc:D1F6BF3FA11FCBC2|rigid:cFpSA8QRKoDWzkr4/xJ/MsQdnpQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75340	uniprotkb:A0A2P0HAK2	intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933.4	intact:EBI-2811673|uniprotkb:Q6KWL7|uniprotkb:E9R2F2|uniprotkb:Q81UK8	psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym)	psi-mi:a0a2p0hak2_bacan(display_long)|uniprotkb:GBAA_0860(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811677|imex:IM-13779-1557	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915.9(gene)|ensembl:ENST00000264933.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0014029""(neural crest formation)|go:""GO:0014032""(neural crest cell development)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0034605""(cellular response to heat)|go:""GO:0036324""(vascular endothelial growth factor receptor-2 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:1902527""(positive regulation of protein monoubiquitination)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR051426|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|dip:DIP-33217N|panther:PTHR46212(orthology-group)"	refseq:WP_000658120.1|interpro:IPR026838	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606	rogid:qmS6oUIKMrlit4ipqga1NQKH9CI1392	intact-crc:593A40198C3B98C6|rigid:SdGxfHTpdLHQmpnC/qMVTDt/p7k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9X365	uniprotkb:P04637	intact:EBI-2811711|uniprotkb:A0A0F7RN80	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5|ensembl:ENSP00000269305.4|ensembl:ENSP00000391478.2|ensembl:ENSP00000424104.2|ensembl:ENSP00000426252.2|ensembl:ENSP00000519624.1|ensembl:ENSP00000519626.1	psi-mi:q9x365_bacan(display_long)|uniprotkb:GBAA_pXO1_0130(locus name)	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811714|imex:IM-13779-1556	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_052791.1|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR028357|go:""GO:0000271""(polysaccharide biosynthetic process)|go:""GO:0003979""(UDP-glucose 6-dehydrogenase activity)|go:""GO:0006065""(UDP-glucuronate biosynthetic process)|go:""GO:0051287""(NAD binding)|refseq:WP_001027044.1|interpro:IPR036220|interpro:IPR036291"	"efo:""Orphanet:1333""|efo:""Orphanet:145""|efo:""Orphanet:1501""|efo:""Orphanet:210159""|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:251899""|efo:""Orphanet:2807""|efo:""Orphanet:293199""|efo:""Orphanet:3318""|efo:""Orphanet:524""|efo:""Orphanet:585909""|efo:""Orphanet:668""|efo:""Orphanet:67038""|efo:""Orphanet:70573""|efo:""Orphanet:96253""|efo:""Orphanet:99756""|efo:""Orphanet:99757""|panther:PTHR11447(orthology-group)|efo:""Orphanet:52688""|ensembl:ENSG00000141510.19(gene)|ensembl:ENST00000269305.9(transcript)|ensembl:ENST00000445888.6(transcript)|ensembl:ENST00000503591.2(transcript)|ensembl:ENST00000508793.6(transcript)|ensembl:ENST00000714357.1(transcript)|ensembl:ENST00000714359.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000423""(mitophagy)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001094""(TFIID-class transcription factor complex binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001756""(somitogenesis)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0002020""(protease binding)|go:""GO:0002039""(p53 binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002309""(T cell proliferation involved in immune response)|go:""GO:0002326""(B cell lineage commitment)|go:""GO:0002360""(T cell lineage commitment)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005507""(copper ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005657""(replication fork)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006914""(autophagy)|go:""GO:0006974""(DNA damage response)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0006978""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:0006983""(ER overload response)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007369""(gastrulation)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007406""(negative regulation of neuroblast proliferation)|go:""GO:0008104""(protein localization)|go:""GO:0008156""(negative regulation of DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0009299""(mRNA transcription)|go:""GO:0009303""(rRNA transcription)|go:""GO:0009651""(response to salt stress)|go:""GO:0010165""(response to X-ray)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010659""(cardiac muscle cell apoptotic process)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016032""(viral process)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016605""(PML body)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019661""(glucose catabolic process to lactate via pyruvate)|go:""GO:0019899""(enzyme binding)|go:""GO:0021549""(cerebellum development)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034103""(regulation of tissue remodeling)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035033""(histone deacetylase regulator activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035794""(positive regulation of mitochondrial membrane permeability)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036310""(ATP-dependent DNA/DNA annealing activity)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043073""(germ cell nucleus)|go:""GO:0043153""(entrainment of circadian clock by photoperiod)|go:""GO:0043504""(mitochondrial DNA repair)|go:""GO:0043516""(regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045899""(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048512""(circadian behavior)|go:""GO:0048539""(bone marrow development)|go:""GO:0048568""(embryonic organ development)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051097""(negative regulation of helicase activity)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051276""(chromosome organization)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070242""(thymocyte apoptotic process)|go:""GO:0070245""(positive regulation of thymocyte apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071494""(cellular response to UV-C)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0072331""(signal transduction by p53 class mediator)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0072717""(cellular response to actinomycin D)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090399""(replicative senescence)|go:""GO:0090403""(oxidative stress-induced premature senescence)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097252""(oligodendrocyte apoptotic process)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901525""(negative regulation of mitophagy)|go:""GO:1902108""(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902253""(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:1902749""(regulation of cell cycle G2/M phase transition)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903451""(negative regulation of G1 to G0 transition)|go:""GO:1903799""(negative regulation of miRNA processing)|go:""GO:1904024""(negative regulation of glucose catabolic process to lactate via pyruvate)|go:""GO:1905856""(negative regulation of pentose-phosphate shunt)|go:""GO:1990144""(intrinsic apoptotic signaling pathway in response to hypoxia)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000269""(regulation of fibroblast apoptotic process)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2000647""(negative regulation of stem cell proliferation)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872(""p53 transactivation domain (TAD)"")|interpro:IPR036674|interpro:IPR040926|mint:P04637|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|rcsb pdb:2AHI|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3Q06|rcsb pdb:3SAK|rcsb pdb:3TG5|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGL|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:5BUA|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6XRE|rcsb pdb:6ZNC|rcsb pdb:7B46|rcsb pdb:7B47|rcsb pdb:7B48|rcsb pdb:7B49|rcsb pdb:7B4A|rcsb pdb:7B4B|rcsb pdb:7B4C|rcsb pdb:7B4D|rcsb pdb:7B4E|rcsb pdb:7B4F|rcsb pdb:7B4G|rcsb pdb:7B4H|rcsb pdb:7B4N|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7DVD|rcsb pdb:7EAX|rcsb pdb:7EDS|rcsb pdb:7EEU|rcsb pdb:7EL4|rcsb pdb:7NMI|rcsb pdb:7RM4|rcsb pdb:7V97|rcsb pdb:7XZX|rcsb pdb:7XZZ|rcsb pdb:7YGI|rcsb pdb:8A31|rcsb pdb:8A32|rcsb pdb:8A92|rcsb pdb:8CG7|rcsb pdb:8DC4|rcsb pdb:8DC6|rcsb pdb:8DC7|rcsb pdb:8DC8|rcsb pdb:8E7A|rcsb pdb:8E7B|rcsb pdb:8F2H|rcsb pdb:8F2I|rcsb pdb:8GCR|rcsb pdb:8HLL|rcsb pdb:8HLM|rcsb pdb:8HLN|rcsb pdb:8J8N|rcsb pdb:8OXM|rcsb pdb:8OXO|rcsb pdb:8QWK|rcsb pdb:8QWL|rcsb pdb:8QWM|rcsb pdb:8QWN|rcsb pdb:8QWO|rcsb pdb:8QWP|rcsb pdb:8R1F|rcsb pdb:8R1G|rcsb pdb:8UQR|rcsb pdb:8WD2|rcsb pdb:8XP5|rcsb pdb:9C5S|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-9723905|reactome:R-HSA-9725370|reactome:R-HSA-9758274|reactome:R-HSA-9819196|reactome:R-HSA-983231|reactome:R-HSA-9833482|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|refseq:NP_001119590.1|refseq:NP_001263624.1|refseq:NP_001263625.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|ensembl:ENSP00000269305.4|ensembl:ENST00000420246.6|ensembl:ENSP00000391127.2|ensembl:ENSP00000391478.2|ensembl:ENST00000455263.6|ensembl:ENSP00000398846.2|ensembl:ENSP00000426252.2|ensembl:ENST00000504290.5|ensembl:ENSP00000484409.1|ensembl:ENST00000504937.5|ensembl:ENSP00000481179.1|ensembl:ENSP00000424104.2|ensembl:ENST00000509690.6|ensembl:ENSP00000425104.2|ensembl:ENST00000510385.5|ensembl:ENSP00000478499.1|ensembl:ENST00000610292.4|ensembl:ENSP00000478219.1|ensembl:ENST00000610538.4|ensembl:ENSP00000480868.1|ensembl:ENST00000619485.4|ensembl:ENSP00000482537.1|ensembl:ENST00000620739.4|ensembl:ENSP00000481638.1|ensembl:ENST00000622645.4|ensembl:ENSP00000482222.1|ensembl:ENSP00000519624.1|ensembl:ENSP00000519626.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:DJdOP3XbPA2jandJxLQudB6VJnU1392	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	intact-crc:D258990E955146AA|rigid:AICDnJV/DjAbQMUHfKKgR4Gg7ak	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:Q9NP74	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-2811699|uniprotkb:Q9NPS0|uniprotkb:Q9NPM6|uniprotkb:Q9NPM5|uniprotkb:Q9H7E6|ensembl:ENSP00000263174.4	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:palmd_human(display_long)|uniprotkb:PALMD(gene name)|psi-mi:PALMD(display_short)|uniprotkb:C1orf11(gene name synonym)|uniprotkb:PALML(gene name synonym)|uniprotkb:Paralemmin-like protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811696|imex:IM-13779-1558	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"refseq:NP_060204.1|ensembl:ENSG00000099260.12(gene)|ensembl:ENST00000263174.9(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016020""(membrane)|go:""GO:0043197""(dendritic spine)|interpro:IPR004965(Paralemmin)|panther:PTHR46881(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:M0wCVUG2QhiZF7ufx3A9tP2BHY09606	intact-crc:9B2045C79A121C18|rigid:+bOv8Vn6Q1B9TVYlp6yiAFdgjmU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00376	uniprotkb:A0A6L8PQC3	intact:EBI-2811724	intact:EBI-2811440|uniprotkb:Q6I444|uniprotkb:Q6KXV4|uniprotkb:E9QQR3|uniprotkb:E9QQR4|uniprotkb:A0A2P0H9A7|uniprotkb:Q81ZA2	psi-mi:o00376_human(display_long)	psi-mi:a0a6l8pqc3_bacan(display_long)|uniprotkb:GBAA_0370(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811721|imex:IM-13779-1561	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR042566|interpro:IPR004244(Transposase, L1)|go:""GO:0004803""(transposase activity)|interpro:IPR035300|interpro:IPR035301|interpro:IPR043636"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|refseq:WP_000410216.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VAmTDezlE5ojKqzukuXq3RiDIiM9606	rogid:+ivfvCodXbxbEMok2GCUbqdVQA01392	intact-crc:FDD3380A7D46B5E1|rigid:2NZ395bdnGSfuddVIWDTH8wUUQI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VE1	uniprotkb:P16083	intact:EBI-2811760|uniprotkb:Q6I4E3|uniprotkb:Q6KY46	intact:EBI-358466|uniprotkb:B2R492|uniprotkb:Q5TD04|ensembl:ENSP00000337773.2|ensembl:ENSP00000369795.1|ensembl:ENSP00000369822.4	psi-mi:ch60_bacan(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:BAS0253(locus name)|uniprotkb:BA_0267(locus name)|uniprotkb:GBAA_0267(locus name)	"psi-mi:nqo2_human(display_long)|uniprotkb:NQO2(gene name)|psi-mi:NQO2(display_short)|uniprotkb:NMOR2(gene name synonym)|uniprotkb:NRH dehydrogenase [quinone] 2(gene name synonym)|uniprotkb:""NRH:quinone oxidoreductase 2""(gene name synonym)|uniprotkb:Quinone reductase 2(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811757|imex:IM-13779-1560	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016853""(isomerase activity)|go:""GO:0042026""(protein refolding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|refseq:WP_001030000.1|interpro:IPR027410|refseq:NP_842820.1|refseq:YP_026537.1"	"ensembl:ENSG00000124588.22(gene)|ensembl:ENST00000338130.7(transcript)|ensembl:ENST00000380430.6(transcript)|ensembl:ENST00000380455.11(transcript)|go:""GO:0001512""(dihydronicotinamide riboside quinone reductase activity)|go:""GO:0003955""(""NAD(P)H dehydrogenase (quinone) activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009055""(electron transfer activity)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016661""(oxidoreductase activity, acting on other nitrogenous compounds as donors)|go:""GO:0031404""(chloride ion binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071949""(FAD binding)|go:""GO:1901662""(quinone catabolic process)|go:""GO:1904408""(melatonin binding)|go:""GO:1905594""(resveratrol binding)|interpro:IPR003680(Flavodoxin-like fold)|interpro:IPR029039|interpro:IPR051545|mint:P16083|rcsb pdb:1QR2|rcsb pdb:1SG0|rcsb pdb:1XI2|rcsb pdb:1ZX1|rcsb pdb:2BZS|rcsb pdb:2QMY|rcsb pdb:2QMZ|rcsb pdb:2QR2|rcsb pdb:2QWX|rcsb pdb:2QX4|rcsb pdb:2QX6|rcsb pdb:2QX8|rcsb pdb:2QX9|rcsb pdb:3FW1|rcsb pdb:3G5M|rcsb pdb:3GAM|rcsb pdb:3NFR|rcsb pdb:3NHF|rcsb pdb:3NHJ|rcsb pdb:3NHK|rcsb pdb:3NHL|rcsb pdb:3NHP|rcsb pdb:3NHR|rcsb pdb:3NHS|rcsb pdb:3NHU|rcsb pdb:3NHW|rcsb pdb:3NHY|rcsb pdb:3O2N|rcsb pdb:3O73|rcsb pdb:3OVM|rcsb pdb:3OWH|rcsb pdb:3OWX|rcsb pdb:3OX1|rcsb pdb:3OX2|rcsb pdb:3OX3|rcsb pdb:3TE7|rcsb pdb:3TEM|rcsb pdb:3TZB|rcsb pdb:3UXE|rcsb pdb:3UXH|rcsb pdb:4FGJ|rcsb pdb:4FGK|rcsb pdb:4FGL|rcsb pdb:4GQI|rcsb pdb:4GR9|rcsb pdb:4QOD|rcsb pdb:4QOE|rcsb pdb:4QOF|rcsb pdb:4QOG|rcsb pdb:4QOH|rcsb pdb:4QOI|rcsb pdb:4QOJ|rcsb pdb:4U7F|rcsb pdb:4U7G|rcsb pdb:4U7H|rcsb pdb:4XDG|rcsb pdb:4XDH|rcsb pdb:4ZVK|rcsb pdb:4ZVL|rcsb pdb:4ZVM|rcsb pdb:4ZVN|rcsb pdb:5BUC|rcsb pdb:5LBT|rcsb pdb:5LBU|rcsb pdb:5LBW|rcsb pdb:5LBY|rcsb pdb:5LBZ|rcsb pdb:7O4D|reactome:R-HSA-211945|refseq:NP_000895.2|refseq:NP_001277150.1|refseq:NP_001305869.1|efo:""Orphanet:227535""|dip:DIP-39704N|panther:PTHR10204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:rfS7W7PjZAE/lCghNeZHC3DI9IU1392	rogid:e23niMWdj6fUH4WR3K6sUCTM0KE9606	intact-crc:E228CD06CADE896D|rigid:dL4qlo57jY+Q4r7AUWmFm/0f/8E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AGH4	uniprotkb:P20393	intact:EBI-2811747|uniprotkb:Q6KPR0|uniprotkb:Q6HVI9|uniprotkb:E9QZA8|uniprotkb:E9QZA9|uniprotkb:Q81Y98|uniprotkb:A0A0F7REA7	intact:EBI-2811738|uniprotkb:Q15304|uniprotkb:Q0P5Z4|ensembl:ENSP00000246672.3	psi-mi:a0a6h3agh4_bacan(display_long)|uniprotkb:parE(gene name)|psi-mi:parE(display_short)|uniprotkb:Topoisomerase IV subunit B(gene name synonym)|uniprotkb:GBAA_3657(locus name)	psi-mi:nr1d1_human(display_long)|uniprotkb:NR1D1(gene name)|psi-mi:NR1D1(display_short)|uniprotkb:EAR1(gene name synonym)|uniprotkb:HREV(gene name synonym)|uniprotkb:THRAL(gene name synonym)|uniprotkb:Rev-erbA-alpha(gene name synonym)|uniprotkb:V-erbA-related protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811744|imex:IM-13779-1562	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011557(DNA gyrase, subunit B)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR005740(DNA topoisomerase IV, subunit B, Gram-positive)|interpro:IPR006171(TOPRIM)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0006265""(DNA topological change)|go:""GO:0007059""(chromosome segregation)|go:""GO:0034335""(DNA negative supercoiling activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_001062204.1|interpro:IPR036890|interpro:IPR000565(DNA topoisomerase, type IIA, subunit B)"	"refseq:NP_068370.1|ensembl:ENSG00000126368.6(gene)|ensembl:ENST00000246672.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001678""(intracellular glucose homeostasis)|go:""GO:0003707""(nuclear steroid receptor activity)|go:""GO:0004879""(nuclear receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005978""(glycogen biosynthetic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009755""(hormone-mediated signaling pathway)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016604""(nuclear body)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0020037""(heme binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030425""(dendrite)|go:""GO:0031648""(protein destabilization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0034144""(negative regulation of toll-like receptor 4 signaling pathway)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042749""(regulation of circadian sleep/wake cycle)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043197""(dendritic spine)|go:""GO:0044321""(response to leptin)|go:""GO:0045598""(regulation of fat cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0060086""(circadian temperature homeostasis)|go:""GO:0061178""(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0061469""(regulation of type B pancreatic cell proliferation)|go:""GO:0061889""(negative regulation of astrocyte activation)|go:""GO:0070859""(positive regulation of bile acid biosynthetic process)|go:""GO:0070888""(E-box binding)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0150079""(negative regulation of neuroinflammatory response)|go:""GO:1903979""(negative regulation of microglial cell activation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR050234|mint:P20393|rcsb pdb:1A6Y|rcsb pdb:1GA5|rcsb pdb:1HLZ|rcsb pdb:3N00|rcsb pdb:8D8I|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-9707616|dip:DIP-48396N|panther:PTHR24082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/23	rogid:yUlUe2myCjax59Zrv/o54Ei+VvU1392	rogid:UfaVQzUQ3wD4xDBh1sjp+eaawY89606	intact-crc:AE13F6B1E10E31BD|rigid:319d8EqPiRQTPSPBqILtQLcW8pg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81MN9	uniprotkb:Q9UHY1	intact:EBI-2810639|uniprotkb:Q6HU35|uniprotkb:Q6KNB9	intact:EBI-749731|uniprotkb:Q53FZ5|uniprotkb:Q96SU3|uniprotkb:B3KV40|uniprotkb:D6W558|ensembl:ENSP00000233557.3|ensembl:ENSP00000369181.3	psi-mi:ppk1_bacan(display_long)|uniprotkb:ppk(gene name)|psi-mi:ppk(display_short)|uniprotkb:ATP-polyphosphate phosphotransferase(gene name synonym)|uniprotkb:Polyphosphoric acid kinase(gene name synonym)|uniprotkb:BA_4208(locus name)|uniprotkb:GBAA_4208(locus name)|uniprotkb:BAS3903(locus name)	psi-mi:nrbp_human(display_long)|uniprotkb:NRBP1(gene name)|psi-mi:NRBP1(display_short)|uniprotkb:BCON3(gene name synonym)|uniprotkb:NRBP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811731|imex:IM-13779-1559	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003414(Polyphosphate kinase)|interpro:IPR025198|interpro:IPR025200|interpro:IPR024953|go:""GO:0005524""(ATP binding)|go:""GO:0006799""(polyphosphate biosynthetic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0009358""(polyphosphate kinase complex)|go:""GO:0046872""(metal ion binding)|refseq:WP_000423561.1|interpro:IPR036830|interpro:IPR036832|interpro:IPR041108|refseq:NP_846443.1|refseq:YP_030153.1"	"refseq:NP_037524.1|ensembl:ENSG00000115216.14(gene)|refseq:NP_001308286.1|refseq:NP_001308287.1|refseq:NP_001308288.1|refseq:NP_001308290.1|refseq:NP_001308291.1|refseq:NP_001308292.1|ensembl:ENST00000233557.7(transcript)|ensembl:ENST00000379852.8(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005938""(cell cortex)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0042803""(protein homodimerization activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR050588|mint:Q9UHY1|reactome:R-HSA-383280|panther:PTHR24361(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XAQtpZmDcBUTqfHyM89FQx4seQo1392	rogid:goSncKy0TZmmVuw5UPUDsCiAzkk9606	intact-crc:8C2A1575C8BD89EC|rigid:irq5d1AtkrBZotYLdwKsA7R6zKQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7GZT9	uniprotkb:P19838	intact:EBI-2811785|uniprotkb:Q6KMK6|uniprotkb:Q6HTB4|uniprotkb:E9R4L1|uniprotkb:E9R4L2|uniprotkb:A0A2P0HJ67|uniprotkb:Q81LW2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l7gzt9_bacan(display_long)|uniprotkb:GBAA_4497(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811782|imex:IM-13779-1563	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR050515|go:""GO:0005886""(plasma membrane)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008658""(penicillin binding)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|go:""GO:0071972""(peptidoglycan L,D-transpeptidase activity)|refseq:WP_000039017.1|interpro:IPR036138"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:5VOSZ7DqTA+TtGLOAeoQ3SrBB5Q1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:D494B9A7BCF45900|rigid:zMuvIjmz578aiQb8yR9C9eZZGr4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q3BBV0	uniprotkb:A0A6L8PC29	intact:EBI-2804530|uniprotkb:Q9C0H0|uniprotkb:Q8N4E8|uniprotkb:S4R3K2	intact:EBI-2810801|uniprotkb:Q6KRM4|uniprotkb:Q6HXJ8|uniprotkb:E9QRE3|uniprotkb:E9QRE4|uniprotkb:A0A2P0HF49|uniprotkb:Q81PD4	psi-mi:nbpf1_human(display_long)|uniprotkb:KIAA1693(gene name synonym)|uniprotkb:NBPF1(gene name)|psi-mi:NBPF1(display_short)|uniprotkb:Neuroblastoma breakpoint family member 1(gene name synonym)	psi-mi:a0a6l8pc29_bacan(display_long)|uniprotkb:GBAA_2876(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811807|imex:IM-13779-1564	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060410.2|interpro:IPR010630(Protein of unknown function DUF1220)|go:""GO:0005737""(cytoplasm)|interpro:IPR055306|mint:Q3BBV0|ensembl:ENST00000430580.6|ensembl:ENSP00000474456.1|ensembl:ENSG00000219481.11|panther:PTHR14199(orthology-group)"	refseq:WP_001062740.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:df9dRNH9FlktRbcB4eZJiICNysA9606	rogid:4BbTj8554Gwm4rVypGL1Pva9DGE1392	intact-crc:40795B16C86E24A0|rigid:AlYhRiTSOACemgNtpdWwMzA4Oak	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75323	uniprotkb:A0A6H3ADV2	intact:EBI-307133|uniprotkb:O43801|uniprotkb:Q53X96|uniprotkb:C9IYJ3|ensembl:ENSP00000313050.3	intact:EBI-2811770|uniprotkb:Q6KSQ5|uniprotkb:Q6HYQ2|uniprotkb:E9RE07|uniprotkb:E9RE08|uniprotkb:Q81QI2|uniprotkb:A0A0J1HNX0	psi-mi:nips2_human(display_long)|uniprotkb:NIPSNAP2(gene name)|psi-mi:NIPSNAP2(display_short)|uniprotkb:GBAS(gene name synonym)|uniprotkb:Glioblastoma-amplified sequence(gene name synonym)	psi-mi:a0a6h3adv2_bacan(display_long)|uniprotkb:GBAA_2443(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811775|imex:IM-13779-1565	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001189398.1|refseq:NP_001474.1|ensembl:ENSG00000146729.10(gene)|ensembl:ENST00000322090.8(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:1901843""(positive regulation of high voltage-gated calcium channel activity)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|interpro:IPR051557|mint:O75323|reactome:R-HSA-9013407|reactome:R-HSA-9013409|dip:DIP-33564N|panther:PTHR21017(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015421""(ABC-type oligopeptide transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000834766.1|interpro:IPR039421|interpro:IPR036640"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:sfBQGdtSVoH21kBu/Bz9x8x3KWU9606	rogid:lB+oHmo0TrFTnO3aanZonqZ3L0Y1392	intact-crc:6F77D25F47267A3E|rigid:wAj4+utJK5rzyRYKcacSBd1ZzUQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81S14	uniprotkb:Q9Y6Q9	intact:EBI-2811794|uniprotkb:Q6I094|uniprotkb:Q6KU68	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066.3|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	psi-mi:mtad_bacan(display_long)|uniprotkb:mtaD(gene name)|psi-mi:mtaD(display_short)|uniprotkb:BA_1865(locus name)|uniprotkb:GBAA_1865(locus name)|uniprotkb:BAS1729(locus name)	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811800|imex:IM-13779-1566	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR023512|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR050287|go:""GO:0046872""(metal ion binding)|go:""GO:0050270""(S-adenosylhomocysteine deaminase activity)|go:""GO:0090614""(5'-methylthioadenosine deaminase activity)|interpro:IPR032466|refseq:NP_844282.1|refseq:YP_027994.1"	"refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151.19(gene)|ensembl:ENST00000371998.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035624""(receptor transactivation)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043697""(cell dedifferentiation)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070561""(vitamin D receptor signaling pathway)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|dip:DIP-30876N|ensembl:ENST00000371997.3|ensembl:ENSP00000361065.3|ensembl:ENSP00000361066.3|ensembl:ENST00000372004.7|ensembl:ENSP00000361073.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/12	rogid:TDYnZJrYplZEtZNuGj+DQVH3gl81392	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	intact-crc:44017F795E235BCC|rigid:KRNqs3PjDjvZdyW4UQzGCtPnTfM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96T58	uniprotkb:A0A6L7H1G2	intact:EBI-765739|uniprotkb:Q9UQ01|uniprotkb:Q9Y556|uniprotkb:Q9H9A8|uniprotkb:Q9NWH5|ensembl:ENSP00000364912.3|intact:EBI-28975565	intact:EBI-2809927	psi-mi:mint_human(display_long)|uniprotkb:SPEN homolog(gene name synonym)|uniprotkb:SMART/HDAC1-associated repressor protein(gene name synonym)|uniprotkb:KIAA0929(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:SHARP(gene name synonym)|uniprotkb:SPEN(gene name)|psi-mi:SPEN(display_short)	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811814|imex:IM-13779-1567	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1606""|ensembl:ENSG00000065526.13(gene)|ensembl:ENST00000375759.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034172|interpro:IPR034173|interpro:IPR034174|interpro:IPR034175|interpro:IPR035979|interpro:IPR049093|interpro:IPR049094|interpro:IPR049095|mint:Q96T58|rcsb pdb:1OW1|rcsb pdb:2RT5|rcsb pdb:4P6Q|rcsb pdb:7Z1K|reactome:R-HSA-9013422|refseq:NP_055816.2|dip:DIP-34569N|efo:""Orphanet:662234""|panther:PTHR23189(orthology-group)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:m7bdkKVATaG4dkFG/BYXRn4jOIk9606	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	intact-crc:72B7822288C6CFE9|rigid:KEuTzAU8RlmxZz5rfp9IQQhX34k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5HYC2	uniprotkb:A0A6L7H1G2	intact:EBI-948754|intact:EBI-28977075|uniprotkb:A8MTP2|uniprotkb:Q4VXA2|uniprotkb:Q8IVE5|uniprotkb:B9EGW7|ensembl:ENSP00000382815.3	intact:EBI-2809927	psi-mi:brd10_human(display_long)|uniprotkb:BRD10(gene name)|psi-mi:BRD10(display_short)|uniprotkb:KIAA2026(gene name synonym)	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811852|imex:IM-13779-1572	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001017969.2|refseq:XP_005251442.1|refseq:XP_011516063.1|refseq:XP_016869821.1|refseq:XP_016869822.1|refseq:XP_016869823.1|ensembl:ENSG00000183354.12(gene)|ensembl:ENST00000399933.8(transcript)|go:""GO:0005634""(nucleus)|interpro:IPR001487(Bromodomain)|interpro:IPR036427|interpro:IPR040214|panther:PTHR31095(orthology-group)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YFhpi0l2vbyI+RDf+lYQUCb1kIc9606	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	intact-crc:ED88E833250CA511|rigid:iDyIvR4+r7bsHv5yhX9uLO09Nxk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14618	uniprotkb:A0A0F7RE19	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	intact:EBI-2809783|uniprotkb:Q6KPM6|uniprotkb:Q6HVF7|uniprotkb:E9QS28|uniprotkb:E9QS29|uniprotkb:Q81Y62	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	psi-mi:a0a0f7re19_bacan(display_long)|uniprotkb:GBAA_3695(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811833|imex:IM-13779-1571	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"interpro:IPR001119(S-layer homology region)|interpro:IPR051465|go:""GO:0030115""(S-layer)|interpro:IPR032247"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rogid:RZeq/OQN8n8nnEe280+/uO/FFX01392	intact-crc:4085DF93B83BA6AA|rigid:q8WgNi20wrMecerMViEc30s+u5Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6AI39	uniprotkb:A0A6L7H5N1	intact:EBI-1012434|uniprotkb:Q5TFZ3|uniprotkb:Q92514|uniprotkb:A1L3W2|ensembl:ENSP00000313933.4|ensembl:ENSP00000377723.1	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:bicrl_human(display_long)|uniprotkb:BICRAL(gene name)|psi-mi:BICRAL(display_short)|uniprotkb:GLTSCR1L(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 1 protein-like(gene name synonym)|uniprotkb:KIAA0240(gene name synonym)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811859|imex:IM-13779-1570	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056164.1|refseq:NP_001305748.1|ensembl:ENSG00000112624.14(gene)|ensembl:ENST00000314073.10(transcript)|ensembl:ENST00000394168.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140288""(GBAF complex)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR015671(Glioma tumour suppressor candidate region gene 1)|interpro:IPR052438|panther:PTHR15572(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wmf9lC4nRlhlduBaz3ZPV8ro3vQ9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:F1EC5CF68C836371|rigid:dMlYRGRIT7D+tCWeTJmAYBj7iBU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AL61	uniprotkb:Q13503	intact:EBI-2811821|uniprotkb:Q6HRW6|uniprotkb:Q6KL70|uniprotkb:E9R688|uniprotkb:E9R689|uniprotkb:Q81KG0|uniprotkb:A0A1Q4M4V8|uniprotkb:A0A2A8YNJ0	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892.3	psi-mi:a0a6h3al61_bacan(display_long)|uniprotkb:GBAA_5039(locus name)	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811826|imex:IM-13779-1568	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000849109.1	"panther:PTHR13381(orthology-group)|refseq:NP_004255.2|ensembl:ENSG00000152944.9(gene)|ensembl:ENST00000282892.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070847""(core mediator complex)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110|dip:DIP-31471N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:wMbQ1UQrOWbq4LXQdUQnaFvEIhU1392	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	intact-crc:26B15DB71538E91D|rigid:kch6b6285ycucr/OSjIeN6XwoPc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2A8YLN2	uniprotkb:Q92845	intact:EBI-2811840|uniprotkb:Q6HQ28|uniprotkb:Q6KJH2|uniprotkb:E9QWM5|uniprotkb:E9QWM6|uniprotkb:Q81JI6|uniprotkb:A0A1J9VMZ0|uniprotkb:A0A2B6C5E0	intact:EBI-954040|uniprotkb:Q9H416|uniprotkb:Q8NHU7|uniprotkb:B2RDL1|uniprotkb:B1AKU4|uniprotkb:B7Z8A3|uniprotkb:F5H591|uniprotkb:B1AKU5|ensembl:ENSP00000354560.2	psi-mi:a0a2a8yln2_bacan(display_long)|uniprotkb:GBAA_5719(locus name)	psi-mi:kifa3_human(display_long)|uniprotkb:Smg GDS-associated protein(gene name synonym)|uniprotkb:KIFAP3(gene name)|psi-mi:KIFAP3(display_short)|uniprotkb:SMAP(gene name synonym)|uniprotkb:KIF3AP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811845|imex:IM-13779-1569	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000160(GGDEF)|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR014528(Signal transduction phosphoesterase predicted, YybT type)|interpro:IPR051319|interpro:IPR038763|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_001113900.1|interpro:IPR049553"	"refseq:NP_001191443.1|refseq:NP_001191445.1|refseq:NP_001191446.1|refseq:NP_055785.2|ensembl:ENSG00000075945.13(gene)|ensembl:ENST00000361580.7(transcript)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0005930""(axoneme)|go:""GO:0007017""(microtubule-based process)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007165""(signal transduction)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007406""(negative regulation of neuroblast proliferation)|go:""GO:0008104""(protein localization)|go:""GO:0010659""(cardiac muscle cell apoptotic process)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016939""(kinesin II complex)|go:""GO:0019894""(kinesin binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0035869""(ciliary transition zone)|go:""GO:0036064""(ciliary basal body)|go:""GO:0044782""(cilium organization)|go:""GO:0046587""(positive regulation of calcium-dependent cell-cell adhesion)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070242""(thymocyte apoptotic process)|go:""GO:0070244""(negative regulation of thymocyte apoptotic process)|go:""GO:0072383""(plus-end-directed vesicle transport along microtubule)|go:""GO:0097542""(ciliary tip)|go:""GO:0098794""(postsynapse)|go:""GO:0098971""(anterograde dendritic transport of neurotransmitter receptor complex)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0120170""(intraciliary transport particle B binding)|go:""GO:1990075""(periciliary membrane compartment)|interpro:IPR000225(Armadillo)|interpro:IPR008658(Kinesin-associated)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q92845|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|panther:PTHR15605(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JltcMS8lgOhx+YbtRKJlzxMbBbM1392	rogid:pEcMuA/HlGJKpLQzlt1/R00TZ3Q9606	intact-crc:67FDED15ECD896C3|rigid:BQeQEmhj/pBL/rKrO3TCmDLv7+Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:A0A6L7HB94	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2811866|uniprotkb:Q6KWZ1|uniprotkb:E9QTY4|uniprotkb:Q81UZ0	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:a0a6l7hb94_bacan(display_long)|uniprotkb:GBAA_0716(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811870|imex:IM-13779-1575	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|interpro:IPR011864(Phosphate ABC transporter, permease protein PstC)|interpro:IPR051124|go:""GO:0005315""(phosphate transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006817""(phosphate ion transport)|refseq:WP_000676681.1|interpro:IPR035906"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:3p9WbhzFIeUl0xBA3Q9TTq6xTvg1392	intact-crc:9506A606BCB90E5C|rigid:atuMKx1AMO6jZ/BSRbVBBrAyIUE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PKS7	uniprotkb:Q9Y4F9	intact:EBI-2809705|uniprotkb:Q6HR58|uniprotkb:Q6KKH5|uniprotkb:E9QWF2|uniprotkb:E9QWF3|uniprotkb:A0A2P0HL14|uniprotkb:Q81XC3	intact:EBI-2798942|uniprotkb:A6NHP2|uniprotkb:Q5VV38|uniprotkb:Q5VV37|uniprotkb:Q9BQ28|uniprotkb:Q13529|ensembl:ENSP00000259698.4|ensembl:ENSP00000482957.1|intact:EBI-12131068|intact:EBI-13096912	psi-mi:a0a6l8pks7_bacan(display_long)|uniprotkb:GBAA_5317(locus name)	psi-mi:ripr2_human(display_long)|uniprotkb:RIPOR2(gene name)|psi-mi:RIPOR2(display_short)|uniprotkb:C6orf32(gene name synonym)|uniprotkb:DIFF48(gene name synonym)|uniprotkb:FAM65B(gene name synonym)|uniprotkb:KIAA0386(gene name synonym)|uniprotkb:PL48(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811901|imex:IM-13779-1574	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR051310|interpro:IPR025278|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|refseq:WP_000455036.1"	"ensembl:ENSG00000111913.20(gene)|ensembl:ENST00000259698.9(transcript)|ensembl:ENST00000613507.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006935""(chemotaxis)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007517""(muscle organ development)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0030175""(filopodium)|go:""GO:0032420""(stereocilium)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060171""(stereocilium membrane)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:1901673""(regulation of mitotic spindle assembly)|go:""GO:1901741""(positive regulation of myoblast fusion)|go:""GO:1903904""(negative regulation of establishment of T cell polarity)|go:""GO:1905872""(negative regulation of protein localization to cell leading edge)|go:""GO:1990869""(cellular response to chemokine)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000391""(positive regulation of neutrophil extravasation)|go:""GO:2000405""(negative regulation of T cell migration)|go:""GO:2001107""(negative regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026136|interpro:IPR031780|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001273375.1|refseq:NP_001273376.1|refseq:NP_055537.2|refseq:NP_056948.2|refseq:XP_016867015.1|refseq:XP_016867016.1|efo:""Orphanet:90636""|panther:PTHR15829(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LEAQuRzrOsJwYgZq7QXDmoKrfqM1392	rogid:c96hMI1PasEb6udn1jNd5ze3fT89606	intact-crc:691BA4AAED706D05|rigid:ktn8ecZ9KbbfV1qU3GbMbtr2kqI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49773	uniprotkb:A0A6L8P1S1	intact:EBI-1054330|uniprotkb:Q9H5W8|ensembl:ENSP00000304229.5	intact:EBI-2811877|uniprotkb:Q6KQU0|uniprotkb:E9R5Q0|uniprotkb:Q81NI4	psi-mi:hint1_human(display_long)|uniprotkb:Protein kinase C inhibitor 1(gene name synonym)|uniprotkb:Protein kinase C-interacting protein 1(gene name synonym)|uniprotkb:HINT1(gene name)|psi-mi:HINT1(display_short)|uniprotkb:HINT(gene name synonym)|uniprotkb:PKCI1(gene name synonym)|uniprotkb:PRKCNH1(gene name synonym)|uniprotkb:Desumoylating isopeptidase HINT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein 1(gene name synonym)	psi-mi:a0a6l8p1s1_bacan(display_long)|uniprotkb:GBAA_3208(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811881|imex:IM-13779-1573	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:324442""|ensembl:ENSG00000169567.13(gene)|ensembl:ENST00000304043.10(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000166""(nucleotide binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006508""(proteolysis)|go:""GO:0007165""(signal transduction)|go:""GO:0009154""(purine ribonucleotide catabolic process)|go:""GO:0016787""(hydrolase activity)|go:""GO:0016926""(protein desumoylation)|go:""GO:0016929""(deSUMOylase activity)|go:""GO:0043530""(adenosine 5'-monophosphoramidase activity)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310(""Histidine triad (HIT) protein"")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|mint:P49773|rcsb pdb:1AV5|rcsb pdb:1KPA|rcsb pdb:1KPB|rcsb pdb:1KPC|rcsb pdb:1KPE|rcsb pdb:1KPF|rcsb pdb:3TW2|rcsb pdb:4EQE|rcsb pdb:4EQG|rcsb pdb:4EQH|rcsb pdb:4ZKL|rcsb pdb:4ZKV|rcsb pdb:5ED3|rcsb pdb:5ED6|rcsb pdb:5EMT|rcsb pdb:5I2E|rcsb pdb:5I2F|rcsb pdb:5IPB|rcsb pdb:5IPC|rcsb pdb:5IPD|rcsb pdb:5IPE|rcsb pdb:5KLY|rcsb pdb:5KLZ|rcsb pdb:5KM0|rcsb pdb:5KM1|rcsb pdb:5KM2|rcsb pdb:5KM3|rcsb pdb:5KM4|rcsb pdb:5KM6|rcsb pdb:5KMA|rcsb pdb:5KMB|rcsb pdb:5KMC|rcsb pdb:5O8I|rcsb pdb:5WA8|rcsb pdb:5WA9|rcsb pdb:5WAA|rcsb pdb:6B42|rcsb pdb:6G9Z|rcsb pdb:6J53|rcsb pdb:6J58|rcsb pdb:6J5S|rcsb pdb:6J5Z|rcsb pdb:6J64|rcsb pdb:6J65|rcsb pdb:6N3V|rcsb pdb:6N3W|rcsb pdb:6N3X|rcsb pdb:6N3Y|rcsb pdb:6YQM|rcsb pdb:7Q2U|rcsb pdb:8P8P|rcsb pdb:8PA6|rcsb pdb:8PA9|rcsb pdb:8PAF|rcsb pdb:8PAI|rcsb pdb:8PWK|rcsb pdb:8WZD|reactome:R-HSA-9824594|reactome:R-HSA-9825892|reactome:R-HSA-9856649|refseq:NP_005331.1|panther:PTHR23089(orthology-group)"	"interpro:IPR004360(Glyoxalase/bleomycin resistance protein/dioxygenase)|interpro:IPR037523|interpro:IPR051785|interpro:IPR029068|go:""GO:0004493""(methylmalonyl-CoA epimerase activity)|go:""GO:0046491""(L-methylmalonyl-CoA metabolic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_001145266.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vXotU/cqS8hSHeBmCk30zSQ9k/E9606	rogid:6MIT7A7jtAT/+5yIJEyb4uwoglk1392	intact-crc:20C3B65E2ACB83B6|rigid:yielVA1K5yfyT4nUCye9oZ0X4Rw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VT8	uniprotkb:O00165	intact:EBI-2811891|uniprotkb:Q6I4U2	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811888|imex:IM-13779-1576	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	intact-crc:E4AA9D98F6C61C22|rigid:Uvhv0EuqZSRekGZcP6JWSuqpwuE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P1I7	uniprotkb:O43491	intact:EBI-2809746|uniprotkb:Q6KXV0|uniprotkb:Q6I440|uniprotkb:E9RCC7|uniprotkb:E9RCC8|uniprotkb:A0A2P0H989|uniprotkb:Q81Z98	intact:EBI-1052044|uniprotkb:Q5T4F0|uniprotkb:B4DHI8|uniprotkb:Q68DV2|uniprotkb:E9PPD9|ensembl:ENSP00000338481.3|ensembl:ENSP00000357110.2	psi-mi:a0a6l8p1i7_bacan(display_long)|uniprotkb:GBAA_0374(locus name)	psi-mi:e41l2_human(display_long)|uniprotkb:Generally expressed protein 4.1(gene name synonym)|uniprotkb:EPB41L2(gene name)|psi-mi:EPB41L2(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811908|imex:IM-13779-1577	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017501(Phage infection protein, YhgE,  C-terminal)|interpro:IPR017500(Phage infection protein, YhgE,  N-terminal)|interpro:IPR051328|go:""GO:0016020""(membrane)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR013525(ABC-2 type transporter)|refseq:WP_000810134.1"	"refseq:NP_001422.1|refseq:NP_001129026.1|refseq:NP_001129027.1|refseq:NP_001239589.1|refseq:XP_011533832.1|refseq:XP_011533836.1|refseq:XP_016865844.1|refseq:XP_016865848.1|refseq:XP_016865849.1|refseq:XP_016865850.1|refseq:XP_016865851.1|dip:DIP-17034N|ensembl:ENSG00000079819.20(gene)|ensembl:ENST00000337057.8(transcript)|ensembl:ENST00000368128.6(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0008091""(spectrin)|go:""GO:0030054""(cell junction)|go:""GO:0030507""(spectrin binding)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0042731""(PH domain binding)|go:""GO:0051301""(cell division)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904778""(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|mint:O43491|reactome:R-HSA-6794361|panther:PTHR23280(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Km4jDuu44pVTrI8b6www/dkgkrY1392	rogid:QvhY6g+bBqTBR8oHl/php27Wb7Y9606	intact-crc:F308A076D0502842|rigid:rjwaSpRKeAgj1OuKdrNV0AmqmVE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HEE9	uniprotkb:Q9HCM1	intact:EBI-2811961|uniprotkb:Q6HT96|uniprotkb:Q6KMI9|uniprotkb:E9RAC2|uniprotkb:E9RAC3|uniprotkb:Q81LU5|uniprotkb:A0A1J9WIU5	intact:EBI-308368|uniprotkb:Q4KN17|uniprotkb:Q9NVL6|uniprotkb:Q9NWP9|uniprotkb:B2RTU5|ensembl:ENSP00000310338.4	psi-mi:a0a6l7hee9_bacan(display_long)|uniprotkb:GBAA_4515(locus name)|uniprotkb:sigA(gene name)|psi-mi:sigA(display_short)	psi-mi:resf1_human(display_long)|uniprotkb:RESF1(gene name)|psi-mi:RESF1(display_short)|uniprotkb:C12orf35(gene name synonym)|uniprotkb:KIAA1551(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811967|imex:IM-13779-1580	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028630|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR050239|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016987""(sigma factor activity)|refseq:WP_000764058.1|interpro:IPR042189|interpro:IPR036388"	"refseq:NP_060639.3|ensembl:ENSG00000174718.12(gene)|ensembl:ENST00000312561.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0042393""(histone binding)|go:""GO:0141005""(transposable element silencing by heterochromatin formation)|go:""GO:1990226""(histone methyltransferase binding)|interpro:IPR027866|mint:Q9HCM1|refseq:XP_005253462.1|refseq:XP_011519024.1|refseq:XP_016875039.1|dip:DIP-37599N|panther:PTHR21604(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:B+oGNayePUrFKBMVM5F7WotZ1Cs1392	rogid:JZhTz9sIotvCEoYh1IrFDhM5KzE9606	intact-crc:6AF7AE95023FD34F|rigid:sPmo+69wgJtQqqQfMVt/TjhnuKA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BPX3	uniprotkb:Q9X2Y1	intact:EBI-970214|uniprotkb:Q9HBI9|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6|ensembl:ENSP00000251496.2	intact:EBI-2811940|uniprotkb:A0A0F7RIB6	psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym)	psi-mi:q9x2y1_bacan(display_long)|uniprotkb:GBAA_pXO1_0015(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811943|imex:IM-13779-1579	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_071741.2|dip:DIP-34891N|ensembl:ENSG00000109805.10(gene)|ensembl:ENST00000251496.7(transcript)|go:""GO:0000779""(condensed chromosome, centromeric region)|go:""GO:0000793""(condensed chromosome)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000796""(condensin complex)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007076""(mitotic chromosome condensation)|go:""GO:0016020""(membrane)|go:""GO:0051301""(cell division)|go:""GO:0051984""(positive regulation of chromosome segregation)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:1905821""(positive regulation of chromosome condensation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|panther:PTHR14418(orthology-group)"	"interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|refseq:NP_052706.1|interpro:IPR029063|go:""GO:0003676""(nucleic acid binding)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0032259""(methylation)|refseq:WP_001236413.1|interpro:IPR046076"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:G45XQBcnTeSunRz57s6lJErxvjo9606	rogid:Tu99i4+SZvgB2cz4qdaNaDDSScU1392	intact-crc:79CAE726EE8CB59A|rigid:IMCyUEyBrWiesPFPrRSGygNlaIE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75534	uniprotkb:A0A6L7HPU1	intact:EBI-719186|uniprotkb:O94961|uniprotkb:Q5TF04|uniprotkb:Q5TF05|uniprotkb:Q68DI9|uniprotkb:Q9Y2S4|uniprotkb:E9PGZ0|uniprotkb:Q68DF1|intact:EBI-1059183|uniprotkb:A8K281|ensembl:ENSP00000351329.4|ensembl:ENSP00000407724.3|ensembl:ENSP00000432958.1|ensembl:ENSP00000508874.1|ensembl:ENSP00000509808.1|ensembl:ENSP00000510208.1|uniprotkb:G5E9Q2|intact:EBI-21358614	intact:EBI-2811931|uniprotkb:Q6HQU7|uniprotkb:Q6KK67|uniprotkb:E9R2W7|uniprotkb:E9R2W8|uniprotkb:Q81X12|uniprotkb:A0A1J9VQC3	psi-mi:csde1_human(display_long)|uniprotkb:Protein UNR(gene name synonym)|uniprotkb:N-ras upstream gene protein(gene name synonym)|uniprotkb:CSDE1(gene name)|psi-mi:CSDE1(display_short)|uniprotkb:D1S155E(gene name synonym)|uniprotkb:KIAA0885(gene name synonym)|uniprotkb:NRU(gene name synonym)|uniprotkb:UNR(gene name synonym)	psi-mi:a0a6l7hpu1_bacan(display_long)|uniprotkb:GBAA_5437(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811928|imex:IM-13779-1581	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001007554.1|refseq:NP_001123995.1|refseq:NP_001229820.1|refseq:NP_001229821.1|refseq:NP_001229822.1|refseq:NP_009089.4|ensembl:ENSG00000009307.17(gene)|ensembl:ENST00000358528.9(transcript)|ensembl:ENST00000438362.7(transcript)|ensembl:ENST00000534699.5(transcript)|ensembl:ENST00000689217.1(transcript)|ensembl:ENST00000689989.1(transcript)|ensembl:ENST00000692719.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0008584""(male gonad development)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0034063""(stress granule assembly)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0070937""(CRD-mediated mRNA stability complex)|go:""GO:0070966""(nuclear-transcribed mRNA catabolic process, no-go decay)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0106002""(mCRD-mediated mRNA stability complex)|go:""GO:0106222""(lncRNA binding)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1905172""(RISC complex binding)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|interpro:IPR024642|mint:O75534|rcsb pdb:1WFQ|rcsb pdb:1X65|rcsb pdb:2YTV|rcsb pdb:2YTX|rcsb pdb:2YTY|panther:PTHR12913(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011608(PRD)|interpro:IPR004701(Phosphotransferase system, fructose subfamily IIA component)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR025943|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000820931.1|interpro:IPR033887|interpro:IPR036390|interpro:IPR036634|interpro:IPR036662"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fpL1bONjNXyXjIO/akUIIoeEGTc9606	rogid:tvq/h2oA/aWYNCnp+DjoR59hDQo1392	intact-crc:7D4BF7A498D8A689|rigid:i1arrpfRSbGuiS2aRu6ZzrI8HFA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PHK5	uniprotkb:Q9BTC0	intact:EBI-2811918|uniprotkb:Q6KMR4|uniprotkb:Q6HTH2|uniprotkb:E9R719|uniprotkb:E9R720|uniprotkb:Q81M19|uniprotkb:A0A0F7RDI0	intact:EBI-739985|uniprotkb:O15043|uniprotkb:A8MY65|uniprotkb:Q3ZTL7|uniprotkb:Q3ZTL8|uniprotkb:Q4VXS1|uniprotkb:Q4VXS2|uniprotkb:Q4VXV8|uniprotkb:Q96D72|uniprotkb:Q9BQW0|uniprotkb:Q9BW03|uniprotkb:Q9H4G6|uniprotkb:Q9H4G7|uniprotkb:Q9NTU8|uniprotkb:Q9NUM8|uniprotkb:Q9UFB6|uniprotkb:B9EH82|uniprotkb:Q4VXV9|uniprotkb:E1P5I1|ensembl:ENSP00000266070.4|ensembl:ENSP00000378752.1|intact:EBI-28975591	psi-mi:a0a6l8phk5_bacan(display_long)|uniprotkb:GBAA_4436(locus name)|uniprotkb:sugE2(gene name)|psi-mi:sugE2(display_short)	psi-mi:dido1_human(display_long)|uniprotkb:DIDO1(gene name)|psi-mi:DIDO1(display_short)|uniprotkb:Death-associated transcription factor 1(gene name synonym)|uniprotkb:C20orf158(gene name synonym)|uniprotkb:DATF1(gene name synonym)|uniprotkb:KIAA0333(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811915|imex:IM-13779-1578	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000390(Small multidrug resistance protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_000312624.1|interpro:IPR045324"	"refseq:NP_001180298.1|refseq:NP_001180299.1|refseq:NP_071388.2|refseq:NP_149072.2|refseq:NP_542986.1|refseq:NP_542987.2|refseq:XP_011526811.1|ensembl:ENSG00000101191.17(gene)|ensembl:ENST00000266070.8(transcript)|ensembl:ENST00000395343.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0097190""(apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR033082|interpro:IPR036575|mint:Q9BTC0|rcsb pdb:2M3H|rcsb pdb:4L7X|reactome:R-HSA-1221632|panther:PTHR11477(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jXYwPvVPcHA7oehMLCdENYLjl8Q1392	rogid:xtp4cq/633PxqppXYlVvameuI7M9606	intact-crc:A03A4310E31F5639|rigid:oV4jbUYMoA4aiD04N5LLgTFG7p8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3P1U0S6	uniprotkb:O00299	intact:EBI-2811950|uniprotkb:Q6KKL9|uniprotkb:E9QRJ8|uniprotkb:Q81XG9	intact:EBI-347404|uniprotkb:Q15089|uniprotkb:Q502X1|ensembl:ENSP00000364934.2|ensembl:ENSP00000364935.2|ensembl:ENSP00000364940.3|ensembl:ENSP00000372896.2|ensembl:ENSP00000372897.2|ensembl:ENSP00000379229.1|ensembl:ENSP00000382926.3|ensembl:ENSP00000382931.1|ensembl:ENSP00000391395.1|ensembl:ENSP00000398056.2|ensembl:ENSP00000400280.1|ensembl:ENSP00000400532.1|ensembl:ENSP00000401292.2|ensembl:ENSP00000404037.1|ensembl:ENSP00000404589.1|ensembl:ENSP00000406088.1|ensembl:ENSP00000406335.2|ensembl:ENSP00000406968.1|ensembl:ENSP00000407429.2|ensembl:ENSP00000407791.2|ensembl:ENSP00000408094.1|ensembl:ENSP00000408357.1|ensembl:ENSP00000409247.1|ensembl:ENSP00000409979.1|ensembl:ENSP00000410965.1|ensembl:ENSP00000412217.1|ensembl:ENSP00000413330.1|ensembl:ENSP00000416211.1|ensembl:ENSP00000477623.1|ensembl:ENSP00000478930.1|ensembl:ENSP00000479501.1|ensembl:ENSP00000479808.1|ensembl:ENSP00000480256.1|ensembl:ENSP00000482255.1|ensembl:ENSP00000484581.1	psi-mi:a0a3p1u0s6_bacan(display_long)|uniprotkb:GBAA_5268(locus name)	psi-mi:clic1_human(display_long)|uniprotkb:CLIC1(gene name)|psi-mi:CLIC1(display_short)|uniprotkb:NCC27(gene name synonym)|uniprotkb:Nuclear chloride ion channel 27(gene name synonym)|uniprotkb:Chloride channel ABP(gene name synonym)|uniprotkb:Regulatory nuclear chloride ion channel protein(gene name synonym)|uniprotkb:G6(gene name synonym)|uniprotkb:Glutaredoxin-like oxidoreductase CLIC1(gene name synonym)|uniprotkb:Glutathione-dependent dehydroascorbate reductase CLIC1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811954|imex:IM-13779-1582	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_011053269.1"	"refseq:NP_001279.2|refseq:NP_001274522.1|refseq:NP_001274523.1|panther:PTHR43920(orthology-group)|ensembl:ENSG00000206394.8(gene)|ensembl:ENSG00000213719.8(gene)|ensembl:ENSG00000223639.6(gene)|ensembl:ENSG00000226248.6(gene)|ensembl:ENSG00000226417.6(gene)|ensembl:ENSG00000226651.6(gene)|ensembl:ENSG00000230685.6(gene)|ensembl:ENST00000375779.6(transcript)|ensembl:ENST00000375780.6(transcript)|ensembl:ENST00000375784.8(transcript)|ensembl:ENST00000383404.6(transcript)|ensembl:ENST00000383405.6(transcript)|ensembl:ENST00000395892.5(transcript)|ensembl:ENST00000400052.7(transcript)|ensembl:ENST00000400058.5(transcript)|ensembl:ENST00000415179.5(transcript)|ensembl:ENST00000418285.6(transcript)|ensembl:ENST00000420458.5(transcript)|ensembl:ENST00000422167.6(transcript)|ensembl:ENST00000423055.5(transcript)|ensembl:ENST00000423143.5(transcript)|ensembl:ENST00000423804.5(transcript)|ensembl:ENST00000425464.6(transcript)|ensembl:ENST00000431921.5(transcript)|ensembl:ENST00000433916.5(transcript)|ensembl:ENST00000434202.5(transcript)|ensembl:ENST00000435242.5(transcript)|ensembl:ENST00000438708.5(transcript)|ensembl:ENST00000438750.5(transcript)|ensembl:ENST00000442045.5(transcript)|ensembl:ENST00000447338.5(transcript)|ensembl:ENST00000447369.5(transcript)|ensembl:ENST00000451546.5(transcript)|ensembl:ENST00000456863.6(transcript)|ensembl:ENST00000457485.6(transcript)|ensembl:ENST00000614673.1(transcript)|ensembl:ENST00000614982.1(transcript)|ensembl:ENST00000616760.1(transcript)|ensembl:ENST00000618288.1(transcript)|ensembl:ENST00000619727.1(transcript)|ensembl:ENST00000621055.1(transcript)|ensembl:ENST00000622613.1(transcript)|go:""GO:0005254""(chloride channel activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0006821""(chloride transport)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031982""(vesicle)|go:""GO:0034707""(chloride channel complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0072562""(blood microparticle)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030259|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|interpro:IPR053823|mint:O00299|rcsb pdb:1K0M|rcsb pdb:1K0N|rcsb pdb:1K0O|rcsb pdb:1RK4|rcsb pdb:3O3T|rcsb pdb:3P8W|rcsb pdb:3P90|rcsb pdb:3QR6|rcsb pdb:3SWL|rcsb pdb:3TGZ|rcsb pdb:3UVH|rcsb pdb:4IQA|rcsb pdb:4JZQ|rcsb pdb:4K0G|rcsb pdb:4K0N|rcsb pdb:7F8R|rcsb pdb:7FBQ"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hjrcwydPWBq88ogxTtvYTY0MLYE1392	rogid:HVux62IcNdqcPgqmlGlIyZTLpFo9606	intact-crc:3B72D488197E68CF|rigid:pd/t5pWx/t7pCyqI+vMct2dvozs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10809	uniprotkb:A0A6L7H1X5	intact:EBI-352528|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|ensembl:ENSP00000340019.2|ensembl:ENSP00000373620.3|ensembl:ENSP00000396460.2|ensembl:ENSP00000402478.2|ensembl:ENSP00000412227.2|ensembl:ENSP00000412717.2|ensembl:ENSP00000414446.2|ensembl:ENSP00000503139.1|ensembl:ENSP00000503894.1|uniprotkb:B7Z712	intact:EBI-2811996|uniprotkb:Q6HW67|uniprotkb:Q6KQC3|uniprotkb:E9QY43|uniprotkb:E9QY44|uniprotkb:Q81N05|uniprotkb:A0A0F7RBD1	psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym)|uniprotkb:Heat shock protein family D member 1(gene name synonym)	psi-mi:a0a6l7h1x5_bacan(display_long)|uniprotkb:GBAA_3414(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811993|imex:IM-13779-1583	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000144381.18(gene)|ensembl:ENST00000345042.6(transcript)|ensembl:ENST00000388968.8(transcript)|ensembl:ENST00000418022.2(transcript)|ensembl:ENST00000426480.2(transcript)|ensembl:ENST00000428204.6(transcript)|ensembl:ENST00000439605.2(transcript)|ensembl:ENST00000452200.6(transcript)|ensembl:ENST00000677913.1(transcript)|ensembl:ENST00000678761.1(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002039""(p53 binding)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0002842""(positive regulation of T cell mediated immune response to tumor cell)|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006457""(protein folding)|go:""GO:0006458""('de novo' protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008035""(high-density lipoprotein particle binding)|go:""GO:0008637""(apoptotic mitochondrial changes)|go:""GO:0009409""(response to cold)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030135""(coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0034186""(apolipoprotein A-I binding)|go:""GO:0034514""(mitochondrial unfolded protein response)|go:""GO:0042026""(protein refolding)|go:""GO:0042100""(B cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0042113""(B cell activation)|go:""GO:0043032""(positive regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045041""(protein import into mitochondrial intermembrane space)|go:""GO:0046696""(lipopolysaccharide receptor complex)|go:""GO:0048291""(isotype switching to IgG isotypes)|go:""GO:0050821""(protein stabilization)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0051604""(protein maturation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:0140494""(migrasome)|go:""GO:0140608""(cysteine-type endopeptidase activator activity)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1900118""(negative regulation of execution phase of apoptosis)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|rcsb pdb:7L7S|rcsb pdb:8G7J|rcsb pdb:8G7K|rcsb pdb:8G7L|rcsb pdb:8G7M|rcsb pdb:8G7N|rcsb pdb:8G7O|rcsb pdb:8U39|reactome:R-HSA-1268020|reactome:R-HSA-8869496|reactome:R-HSA-9837999|reactome:R-HSA-9841251|refseq:NP_002147.2|refseq:NP_955472.1|efo:""Orphanet:100994""|efo:""Orphanet:280288""|dip:DIP-58N|panther:PTHR45633(orthology-group)"	"interpro:IPR029063|go:""GO:0008757""(S-adenosylmethionine-dependent methyltransferase activity)|refseq:WP_000679183.1|interpro:IPR013216(Methyltransferase type 11)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606	rogid:c2E/wfylV5PNEtqOeXq1w1JUZmg1392	intact-crc:1494D18E97AEF31A|rigid:6pwNb8dLrMzwNKbJ1+lMjs5jdvA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3M2	uniprotkb:A0A0F7RA65	intact:EBI-947308|uniprotkb:Q66GT6|uniprotkb:Q9UIK9|uniprotkb:B2R4S2|ensembl:ENSP00000216029.3|ensembl:ENSP00000380026.2|ensembl:ENSP00000412260.2|ensembl:ENSP00000413934.2	intact:EBI-2812017|uniprotkb:Q6KPF1|uniprotkb:E9RCL2|uniprotkb:Q81XY2	psi-mi:cby1_human(display_long)|uniprotkb:CBY1(gene name)|psi-mi:CBY1(display_short)|uniprotkb:C22orf2(gene name synonym)|uniprotkb:CBY(gene name synonym)|uniprotkb:HRIHFB2025(orf name)|uniprotkb:ARB1(gene name synonym)|uniprotkb:PGEA1(gene name synonym)|uniprotkb:PKD2 interactor, Golgi and endoplasmic reticulum-associated 1(gene name synonym)|uniprotkb:PIGEA-14(gene name synonym)|uniprotkb:Cytosolic leucine-rich protein(gene name synonym)|uniprotkb:ARPP-binding protein(gene name synonym)	psi-mi:a0a0f7ra65_bacan(display_long)|uniprotkb:GBAA_3782(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812021|imex:IM-13779-1584	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100211.12(gene)|ensembl:ENST00000216029.8(transcript)|ensembl:ENST00000396811.6(transcript)|ensembl:ENST00000411557.6(transcript)|ensembl:ENST00000416285.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008104""(protein localization)|go:""GO:0016607""(nuclear speck)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0033504""(floor plate development)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060271""(cilium assembly)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|interpro:IPR028118|mint:Q9Y3M2|rcsb pdb:4WRQ|reactome:R-HSA-3769402|refseq:NP_001002880.2|refseq:NP_056188.1|dip:DIP-29651N|efo:""Orphanet:475""|panther:PTHR21533(orthology-group)"	interpro:IPR006450(Protein of unknown function, phage)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RqvyVBe3nAEf0bYnToiVsM5hLhc9606	rogid:PvTwdDRJwoizvmpqcgqezKI9N541392	intact-crc:3C9BA46A8A8D2CBE|rigid:/5/03CSb8h2lUYtZr6FVrqeswKg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3E2	uniprotkb:A0A3Q0PRD7	intact:EBI-2811974|uniprotkb:Q6NS91|uniprotkb:Q2M2V6|uniprotkb:Q8N117|uniprotkb:Q3ZB81|uniprotkb:Q8N6C2|uniprotkb:Q8N3G3|uniprotkb:Q7RTP1|uniprotkb:Q9NWA3|ensembl:ENSP00000358293.3|ensembl:ENSP00000498136.1	intact:EBI-2810412|uniprotkb:Q6KSP1|uniprotkb:Q6HYP0|uniprotkb:A0A1T3V4S0|uniprotkb:E9R444|uniprotkb:E9R445|uniprotkb:Q81QG7	psi-mi:cc186_human(display_long)|uniprotkb:CCDC186(gene name)|psi-mi:CCDC186(display_short)|uniprotkb:C10orf118(gene name synonym)|uniprotkb:CTCL tumor antigen HD-CL-01/L14-2(gene name synonym)	psi-mi:a0a3q0prd7_bacan(display_long)|uniprotkb:GBAA_2458(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2811986|imex:IM-13779-1585	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060487.2|refseq:NP_694981.1|refseq:NP_001308758.1|ensembl:ENSG00000165813.20(gene)|ensembl:ENST00000369287.8(transcript)|ensembl:ENST00000648613.1(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0009617""(response to bacterium)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035773""(insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0099518""(vesicle cytoskeletal trafficking)|interpro:IPR038830|mint:Q7Z3E2|dip:DIP-47298N|panther:PTHR18911(orthology-group)"	interpro:IPR008863(Toxic anion resistance)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jP5a23xDi3eH2ATeXCAaJUz7BM89606	rogid:yFhxdvzsJZtdS3cPPgkYzGM4tvA1392	intact-crc:72854AA25FAF8BDD|rigid:1/SbFUFDhSUbZArytterRRj59Jg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AEB7	uniprotkb:P00746	intact:EBI-2812008|uniprotkb:Q6KW05|uniprotkb:Q6I269|uniprotkb:E9RD61|uniprotkb:E9RD62|uniprotkb:Q81TY3|uniprotkb:A0A0F7RL82	intact:EBI-1223696|uniprotkb:Q5U5S1|uniprotkb:Q86VJ5|uniprotkb:Q8N4E0|uniprotkb:Q8WZB4|uniprotkb:B4DV76|ensembl:ENSP00000332139.4|ensembl:ENSP00000478745.1	psi-mi:a0a6h3aeb7_bacan(display_long)|uniprotkb:GBAA_1118(locus name)	psi-mi:cfad_human(display_long)|uniprotkb:CFD(gene name)|psi-mi:CFD(display_short)|uniprotkb:DF(gene name synonym)|uniprotkb:PFD(gene name synonym)|uniprotkb:C3 convertase activator(gene name synonym)|uniprotkb:Properdin factor D(gene name synonym)|uniprotkb:Adipsin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812005|imex:IM-13779-1586	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR050351|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016036""(cellular response to phosphate starvation)|interpro:IPR036097|interpro:IPR036890|refseq:WP_001010422.1"	"efo:""Orphanet:169467""|ensembl:ENSG00000197766.9(gene)|ensembl:ENSG00000274619.2(gene)|ensembl:ENST00000327726.11(transcript)|ensembl:ENST00000617994.2(transcript)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0009617""(response to bacterium)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0051604""(protein maturation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:1BIO|rcsb pdb:1DFP|rcsb pdb:1DIC|rcsb pdb:1DST|rcsb pdb:1DSU|rcsb pdb:1FDP|rcsb pdb:1HFD|rcsb pdb:2XW9|rcsb pdb:2XWA|rcsb pdb:2XWB|rcsb pdb:4CBN|rcsb pdb:4CBO|rcsb pdb:4D9R|rcsb pdb:5FBE|rcsb pdb:5FBI|rcsb pdb:5FCK|rcsb pdb:5MT0|rcsb pdb:5MT4|rcsb pdb:5NAR|rcsb pdb:5NAT|rcsb pdb:5NAW|rcsb pdb:5NB6|rcsb pdb:5NB7|rcsb pdb:5NBA|rcsb pdb:5TCA|rcsb pdb:5TCC|rcsb pdb:6FTY|rcsb pdb:6FTZ|rcsb pdb:6FUG|rcsb pdb:6FUH|rcsb pdb:6FUI|rcsb pdb:6FUJ|rcsb pdb:6FUT|rcsb pdb:6QMR|rcsb pdb:6QMT|rcsb pdb:6VMJ|rcsb pdb:6VMK|rcsb pdb:8D95|rcsb pdb:8DEA|rcsb pdb:8DG6|reactome:R-HSA-114608|reactome:R-HSA-173736|reactome:R-HSA-6798695|refseq:NP_001304264.1|refseq:NP_001919.2|panther:PTHR24271(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:A+/Vlv9OA1JWPLI/K0K9D1e+9gU1392	rogid:G9Jd0KXMDGx6ds9rkRNVrrzrgtw9606	intact-crc:DDDB83903A1A9F45|rigid:8KjqypGx9BD8z4kqHv+DqtR+AiY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01889	uniprotkb:P13423	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	intact:EBI-456868|uniprotkb:Q937W2|uniprotkb:Q937W3|uniprotkb:Q9F5R7|uniprotkb:Q9KH69|uniprotkb:Q9RQU2	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:pag_bacan(display_long)|uniprotkb:PA-83(gene name synonym)|uniprotkb:Anthrax toxins translocating protein(gene name synonym)|uniprotkb:pagA(gene name)|psi-mi:pagA(display_short)|uniprotkb:pag(gene name synonym)|uniprotkb:pXO1-110(locus name)|uniprotkb:BXA0164(locus name)|uniprotkb:GBAA_pXO1_0164(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812057|imex:IM-13779-1590	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"mint:P13423|refseq:NP_052806.1|refseq:WP_000746487.1|refseq:WP_000746486.1|refseq:WP_000746488.1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0044533""(obsolete positive regulation of apoptotic process in another organism)|go:""GO:0046872""(metal ion binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0090729""(toxin activity)|interpro:IPR003896(Bacterial exotoxin B)|interpro:IPR011658(PA14)|interpro:IPR027439|interpro:IPR027441|interpro:IPR035088|interpro:IPR035331|interpro:IPR037149|interpro:IPR037524|interpro:IPR048853|rcsb pdb:1ACC|rcsb pdb:1T6B|rcsb pdb:1TZN|rcsb pdb:1TZO|rcsb pdb:3ETB|rcsb pdb:3INO|rcsb pdb:3J9C|rcsb pdb:3KWV|rcsb pdb:3MHZ|rcsb pdb:3Q8A|rcsb pdb:3Q8B|rcsb pdb:3Q8C|rcsb pdb:3Q8E|rcsb pdb:3Q8F|rcsb pdb:3TEW|rcsb pdb:3TEX|rcsb pdb:3TEY|rcsb pdb:3TEZ|rcsb pdb:4EE2|rcsb pdb:4H2A|rcsb pdb:4NAM|rcsb pdb:5FR3|rcsb pdb:6PSN|rcsb pdb:6UJI|rcsb pdb:6UZB|rcsb pdb:6UZD|rcsb pdb:6UZE|rcsb pdb:6VRA|rcsb pdb:6WJJ|rcsb pdb:6ZXJ|rcsb pdb:6ZXK|rcsb pdb:6ZXL|rcsb pdb:7KXR|rcsb pdb:7O85|reactome:R-HSA-5210891|dip:DIP-29841N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	rogid:xLr/ydN4I0qJ46G/8A3JfZqAbyE1392	intact-crc:7E6C3FA31F1C358D|rigid:McbRaHxWM8PaF+dTFJLsdXaT+sg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H2M3	uniprotkb:Q9NWW7	intact:EBI-2812033	intact:EBI-2812028|uniprotkb:Q9H629|uniprotkb:D6W5G3|ensembl:ENSP00000264434.2|ensembl:ENSP00000404515.1	psi-mi:a0a6l7h2m3_bacan(display_long)|uniprotkb:BA_3473(locus name)	psi-mi:cb042_human(display_long)|uniprotkb:C2orf42(gene name)|psi-mi:C2orf42(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812038|imex:IM-13779-1589	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|refseq:NP_845755.2|interpro:IPR050237|go:""GO:0005524""(ATP binding)|go:""GO:0016877""(ligase activity, forming carbon-sulfur bonds)|uniprotkb:A0A0F7RG28(uniprot-removed-ac)|interpro:IPR045851"	"ensembl:ENSG00000115998.8(gene)|ensembl:ENST00000264434.7(transcript)|ensembl:ENST00000420306.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|interpro:IPR026049|interpro:IPR029269|refseq:NP_001335687.1|refseq:NP_001335688.1|refseq:NP_001335689.1|refseq:NP_001335690.1|refseq:NP_001335691.1|refseq:NP_001335692.1|refseq:NP_001335693.1|refseq:NP_060350.1|panther:PTHR13518(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tVv/bFqWNowqNLZ+P/5QYxKMrgE1392	rogid:Pxu26KjINn/euuvhpc7NMqej76Y9606	intact-crc:637BC6F2E9801181|rigid:VCDeaHjgQyXiyYyI/fUej6a8A7Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46379	uniprotkb:A0A6L8PZG6	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2812048|uniprotkb:Q6HW57|uniprotkb:Q6KQB3|uniprotkb:E9R4V0|uniprotkb:E9R4V1|uniprotkb:Q81MZ5|uniprotkb:A0A0F7RBC2	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:a0a6l8pzg6_bacan(display_long)|uniprotkb:GBAA_3424(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812045|imex:IM-13779-1587	author score:4|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|go:""GO:0005886""(plasma membrane)|interpro:IPR050638|refseq:WP_000814716.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:kG2XIUjw1PkmVtYseZf+x+cJfAg1392	intact-crc:73398F1F07B22721|rigid:SOjip25yaNDUrSpVSqf6vHTa6+M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NRM2	uniprotkb:A0A6L8PGF9	intact:EBI-949305|uniprotkb:Q75MZ2|uniprotkb:Q75MZ3|uniprotkb:Q8WY14|ensembl:ENSP00000354501.3	intact:EBI-2812067|uniprotkb:Q6HZF5|uniprotkb:Q6KTE4|uniprotkb:E9R4G8|uniprotkb:E9R4G9|uniprotkb:Q81R82|uniprotkb:A0A0F7RIG7	psi-mi:zn277_human(display_long)|uniprotkb:ZNF277(gene name)|psi-mi:ZNF277(display_short)|uniprotkb:ZNF277P(gene name synonym)|uniprotkb:NRIF4(gene name synonym)|uniprotkb:Nuclear receptor-interacting factor 4(gene name synonym)	psi-mi:a0a6l8pgf9_bacan(display_long)|uniprotkb:GBAA_2174(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812064|imex:IM-13779-1588	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_068834.2|ensembl:ENSG00000198839.10(gene)|ensembl:ENST00000361822.8(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:2000772""(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|panther:PTHR13267(orthology-group)"	"interpro:IPR007536(Protein of unknown function DUF548)|interpro:IPR029063|go:""GO:0008990""(""rRNA (guanine-N2-)-methyltransferase activity"")|refseq:WP_000637445.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LH60QmqqTZD5rgMq1hXWbyCO09s9606	rogid:9J88Y78eGq6GLkPj6dvcpx+fMzY1392	intact-crc:DB94E3EE5273387E|rigid:sTg0ktn1QacUrHQIWTq2xdVFpDc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULJ6	uniprotkb:A0A4Y1WC41	intact:EBI-308362|uniprotkb:Q7Z7E6|uniprotkb:Q5JSH9|ensembl:ENSP00000334474.5	intact:EBI-2811175|uniprotkb:Q6KLQ4|uniprotkb:E9QTZ5|uniprotkb:Q81L03	psi-mi:zmiz1_human(display_long)|uniprotkb:ZMIZ1(gene name)|psi-mi:ZMIZ1(display_short)|uniprotkb:KIAA1224(gene name synonym)|uniprotkb:ZIMP10(gene name synonym)|uniprotkb:RAI17(gene name synonym)|uniprotkb:Retinoic acid-induced protein 17(gene name synonym)|uniprotkb:PIAS-like protein Zimp10(gene name synonym)	psi-mi:a0a4y1wc41_bacan(display_long)|uniprotkb:polA(gene name)|psi-mi:polA(display_short)|uniprotkb:GBAA_4831(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812088|imex:IM-13779-1591	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108175.19(gene)|ensembl:ENST00000334512.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007296""(vitellogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016925""(protein sumoylation)|go:""GO:0021852""(pyramidal neuron migration to cerebral cortex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048589""(developmental growth)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0090398""(cellular senescence)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040797|mint:Q9ULJ6|rcsb pdb:5AIZ|refseq:NP_065071.1|refseq:XP_011538282.1|refseq:XP_016871931.1|efo:""Orphanet:528084""|panther:PTHR10782(orthology-group)"	"interpro:IPR043502|interpro:IPR018320|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR020046|interpro:IPR020045|interpro:IPR002421(5'-3' exonuclease)|interpro:IPR019760|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR002298(DNA polymerase A)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR029060|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006302""(double-strand break repair)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0008409""(5'-3' exonuclease activity)|interpro:IPR054690|refseq:WP_000412819.1|interpro:IPR036279|interpro:IPR036397"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gqMqBRe+muLdsN5jD0SGo6r88a09606	rogid:gn81BLwvkwoLgpPMLb4rhkwHVHg1392	intact-crc:2CB8406C7AA1F6FC|rigid:kZ806rM5cdviLQ4aCoDnrWEFPI8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A1J9WCP3	uniprotkb:P46939	intact:EBI-2812130|uniprotkb:Q6KXZ3|uniprotkb:Q6I487|uniprotkb:E9R189|uniprotkb:E9R190|uniprotkb:Q81ZE1|uniprotkb:A0A0J1HRK2	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|ensembl:ENSP00000356515.3|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40	psi-mi:a0a1j9wcp3_bacan(display_long)|uniprotkb:GBAA_0328(locus name)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812127|imex:IM-13779-1593	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000390(Small multidrug resistance protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_000263260.1|interpro:IPR045324"	"ensembl:ENSG00000152818.20(gene)|ensembl:ENST00000367545.8(transcript)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006936""(muscle contraction)|go:""GO:0007517""(muscle organ development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016020""(membrane)|go:""GO:0017166""(vinculin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030175""(filopodium)|go:""GO:0031527""(filopodium membrane)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042383""(sarcolemma)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0099536""(synaptic signaling)|go:""GO:2000649""(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|interpro:IPR050774|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665|refseq:NP_009055.2|refseq:XP_005267187.1|refseq:XP_011534408.1|dip:DIP-711N|panther:PTHR12268(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:kNnvGEtfbtmZ3WYcCWH4ScQCMOU1392	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	intact-crc:222FF6606E34AE1F|rigid:pQS7xs47Cr1t34EFDYBOfS3lk/k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1WB04	uniprotkb:Q9ULJ6	intact:EBI-2812076|uniprotkb:Q6KK37|uniprotkb:Q6HQR9|uniprotkb:E9R296|uniprotkb:E9R297|uniprotkb:Q81WY3|uniprotkb:A0A1J9VPA6|uniprotkb:A0A0J1HTG5	intact:EBI-308362|uniprotkb:Q7Z7E6|uniprotkb:Q5JSH9|ensembl:ENSP00000334474.5	psi-mi:a0a4y1wb04_bacan(display_long)|uniprotkb:GBAA_5468(locus name)	psi-mi:zmiz1_human(display_long)|uniprotkb:ZMIZ1(gene name)|psi-mi:ZMIZ1(display_short)|uniprotkb:KIAA1224(gene name synonym)|uniprotkb:ZIMP10(gene name synonym)|uniprotkb:RAI17(gene name synonym)|uniprotkb:Retinoic acid-induced protein 17(gene name synonym)|uniprotkb:PIAS-like protein Zimp10(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812081|imex:IM-13779-1594	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010652(Protein of unknown function DUF1232)|interpro:IPR016983(Uncharacterised conserved protein UCP031804)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|refseq:WP_000435503.1"	"ensembl:ENSG00000108175.19(gene)|ensembl:ENST00000334512.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007296""(vitellogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016925""(protein sumoylation)|go:""GO:0021852""(pyramidal neuron migration to cerebral cortex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048589""(developmental growth)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0090398""(cellular senescence)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040797|mint:Q9ULJ6|rcsb pdb:5AIZ|refseq:NP_065071.1|refseq:XP_011538282.1|refseq:XP_016871931.1|efo:""Orphanet:528084""|panther:PTHR10782(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BJqIUz/7uOTqNy4f7DQKBxNl8Pw1392	rogid:gqMqBRe+muLdsN5jD0SGo6r88a09606	intact-crc:636B2A60D7B04B27|rigid:pgm6VADnCzEIF1TCVs95V5Cqqow	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3Q0PRJ6	uniprotkb:P15822	intact:EBI-2810680|uniprotkb:Q6KR31|uniprotkb:Q6HWZ9|uniprotkb:E9R4P7|uniprotkb:E9R4P8|uniprotkb:Q81NS9|uniprotkb:A0A0F7RCF4	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	psi-mi:a0a3q0prj6_bacan(display_long)|uniprotkb:GBAA_3096(locus name)	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812095|imex:IM-13779-1595	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003778(Allophanate hydrolase subunit 2)|interpro:IPR052708|interpro:IPR029000|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NUa3lWGCm+fzNXodfOc6AoaBPi01392	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	intact-crc:171068B2D800D2BA|rigid:bKi4obqB5XepIoCRIE6f7HhW+EA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7GZ58	uniprotkb:Q9P0L0	intact:EBI-2812115|uniprotkb:Q6HS52|uniprotkb:Q6KLF2|uniprotkb:E9RDW1|uniprotkb:E9RDW2|uniprotkb:A0A2P0HK47|uniprotkb:Q81KP7	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880.3	psi-mi:a0a6l7gz58_bacan(display_long)|uniprotkb:GBAA_4946(locus name)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812120|imex:IM-13779-1596	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026533|interpro:IPR050299|interpro:IPR029001|go:""GO:0000166""(nucleotide binding)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_000869926.1"	"refseq:NP_003565.4|refseq:NP_919415.2|ensembl:ENSG00000101558.14(gene)|ensembl:ENST00000400000.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031982""(vesicle)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035627""(ceramide transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0061025""(membrane fusion)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0090114""(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|dip:DIP-41135N|panther:PTHR10809(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:wcST6FeYxMr1CrjUqTkPLwW3nHY1392	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	intact-crc:DAC7E02144813A2A|rigid:48Mu6xhoJQf+mhLQlGY1uJ7P/uY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15822	uniprotkb:A0A384KEI8	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	intact:EBI-2812105|uniprotkb:Q6KM54|uniprotkb:Q6HSW4|uniprotkb:E9R0Z2|uniprotkb:E9R0Z3|uniprotkb:Q81LF9|uniprotkb:A0A0F7R6B3	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	psi-mi:a0a384kei8_bacan(display_long)|uniprotkb:nadB(gene name)|psi-mi:nadB(display_short)|uniprotkb:GBAA_4662(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812102|imex:IM-13779-1592	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	"interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR005288(L-aspartate oxidase)|interpro:IPR027477|go:""GO:0005737""(cytoplasm)|go:""GO:0008734""(L-aspartate oxidase activity)|go:""GO:0034628""('de novo' NAD biosynthetic process from L-aspartate)|refseq:WP_001138517.1|interpro:IPR036188|interpro:IPR037099"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	rogid:teasIDUFp3AIev+D17Bx3hcCV5c1392	intact-crc:D53B47D0E8BE5028|rigid:9IqPoAg/dCIAt0zZ1MeLsc5SEI0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H3M7	uniprotkb:A0A6L8PL93	intact:EBI-1369170|uniprotkb:B4E3D3|uniprotkb:Q16226|uniprotkb:Q6PML0|uniprotkb:Q9BXG9|ensembl:ENSP00000462521.1	intact:EBI-2812142|uniprotkb:Q6HXW8|uniprotkb:Q6KRZ0|uniprotkb:E9R374|uniprotkb:E9R375|uniprotkb:Q81PQ4|uniprotkb:A0A0F7RGT7	psi-mi:txnip_human(display_long)|uniprotkb:TXNIP(gene name)|psi-mi:TXNIP(display_short)|uniprotkb:VDUP1(gene name synonym)|uniprotkb:Vitamin D3 up-regulated protein 1(gene name synonym)|uniprotkb:Thioredoxin-binding protein 2(gene name synonym)	psi-mi:a0a6l8pl93_bacan(display_long)|uniprotkb:ypeB(gene name)|psi-mi:ypeB(display_short)|uniprotkb:GBAA_2747(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812139|imex:IM-13779-1599	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006463.3|refseq:NP_001300901.1|ensembl:ENSG00000265972.6(gene)|ensembl:ENST00000582401.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006954""(inflammatory response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0009749""(response to glucose)|go:""GO:0015031""(protein transport)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032570""(response to progesterone)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051782""(negative regulation of cell division)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0140052""(cellular response to oxidised low-density lipoprotein particle stimulus)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR050357|mint:Q9H3M7|rcsb pdb:4GEI|rcsb pdb:4GEJ|rcsb pdb:4GFX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4ROF|rcsb pdb:4ROJ|rcsb pdb:5CQ2|rcsb pdb:5DF6|rcsb pdb:5DWS|rcsb pdb:5DZD|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9707564|panther:PTHR11188(orthology-group)"	"interpro:IPR014239(Spore germination YpeB)|go:""GO:0009847""(spore germination)|refseq:WP_000943708.1|interpro:IPR025711|interpro:IPR048402"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:jJMKfl1/92UPMTXBLCdu6NcYbjQ9606	rogid:ArcU2AZZMp9ttGHYayHY+K9lpzU1392	intact-crc:963F8B79383DCE20|rigid:uKXXVGAzudCdBhB3TvgTe5xh118	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H1G2	uniprotkb:Q6PKC3	intact:EBI-2809927	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812152|imex:IM-13779-1597	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	intact-crc:A1AFFCEB19450A27|rigid:dMHhcs2dIhKDLARde43TxOXFO4g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81X85	uniprotkb:Q6PKC3	intact:EBI-2812174|uniprotkb:Q6KKE0|uniprotkb:E9RAE3	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	psi-mi:q81x85_bacan(display_long)|uniprotkb:GBAA_5357(locus name)	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812171|imex:IM-13779-1598	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002711(HNH endonuclease)|interpro:IPR003615(HNH nuclease)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0008270""(zinc ion binding)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cvrrKkEnADjyuk0XbSWnTXpzR/01392	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	intact-crc:C6463CE05D63D5C8|rigid:wieKw6AJBQbn2p71KREHFR0Tvzs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PKC3	uniprotkb:A0A6L7H121	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	intact:EBI-2812162|uniprotkb:Q6KPC5|uniprotkb:Q6HV53|uniprotkb:E9QR13|uniprotkb:E9QR14|uniprotkb:Q81XV4|uniprotkb:A0A0F7RA44	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:a0a6l7h121_bacan(display_long)|uniprotkb:GBAA_3814(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812159|imex:IM-13779-1600	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR050750|interpro:IPR029063|go:""GO:0009307""(DNA restriction-modification system)|go:""GO:0032259""(methylation)|go:""GO:0051719""(""DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates"")|go:""GO:0051720""(""DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates"")|refseq:WP_000286272.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:hfAwL7rY7VEKa5dCSgNFS9MoDfw1392	intact-crc:E06B30410FF9A0F5|rigid:lTXs1bDXKfahgVF9e74V+A13Nks	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81MS2	uniprotkb:Q15643	intact:EBI-2812204|uniprotkb:Q6HU64|uniprotkb:Q6KNE9	intact:EBI-1047183|uniprotkb:O14689|uniprotkb:O15154|uniprotkb:O95949|uniprotkb:B2RUT2|uniprotkb:Q6MZL5|ensembl:ENSP00000267622.4	psi-mi:spea_bacan(display_long)|uniprotkb:speA(gene name)|psi-mi:speA(display_short)|uniprotkb:BA_4172(locus name)|uniprotkb:GBAA_4172(locus name)|uniprotkb:BAS3874(locus name)	psi-mi:tripb_human(display_long)|uniprotkb:Golgi-associated microtubule-binding protein 210(gene name synonym)|uniprotkb:Clonal evolution-related gene on chromosome 14 protein(gene name synonym)|uniprotkb:Trip230(gene name synonym)|uniprotkb:TRIP11(gene name)|psi-mi:TRIP11(display_short)|uniprotkb:CEV14(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812201|imex:IM-13779-1603	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000310(Orn/Lys/Arg decarboxylase, major region)|interpro:IPR008286(Orn/Lys/Arg decarboxylase, C-terminal)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR052357|go:""GO:0005737""(cytoplasm)|go:""GO:0008295""(spermidine biosynthetic process)|go:""GO:0008792""(arginine decarboxylase activity)|go:""GO:0009446""(putrescine biosynthetic process)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR036633|refseq:NP_846410.1|refseq:YP_030124.1"	"ensembl:ENSG00000100815.12(gene)|ensembl:ENST00000267622.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002079""(inner acrosomal membrane)|go:""GO:0002081""(outer acrosomal membrane)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003413""(chondrocyte differentiation involved in endochondral bone morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0030133""(transport vesicle)|go:""GO:0031267""(small GTPase binding)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0051216""(cartilage development)|go:""GO:0060122""(inner ear receptor cell stereocilium organization)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0090161""(Golgi ribbon formation)|go:""GO:0099041""(vesicle tethering to Golgi)|interpro:IPR000237(GRIP)|mint:Q15643|reactome:R-HSA-5620924|reactome:R-HSA-6811438|reactome:R-HSA-9703465|refseq:NP_004230.2|dip:DIP-40357N|efo:""Orphanet:166272""|efo:""Orphanet:93299""|panther:PTHR18921(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vpUN3f9QZ8QAbpr42l8aRBtBkj81392	rogid:M/XOdT1ZPDaQqMuBXsAB5p6N9LY9606	intact-crc:DB3799362050A414|rigid:aFvNf0AwDQZmzosf9mi8RdoKg8E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99598	uniprotkb:A0A6L8PNZ7	intact:EBI-21353855|ensembl:ENSP00000355599.3|uniprotkb:B1APC6	intact:EBI-2812182|uniprotkb:Q6HZV9|uniprotkb:Q6KTU1|uniprotkb:E9QZ89|uniprotkb:E9QZ90|uniprotkb:A0A2P0HD89|uniprotkb:Q81RN5	psi-mi:tsnax_human(display_long)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym)|uniprotkb:Translin-associated factor X(gene name synonym)	psi-mi:a0a6l8pnz7_bacan(display_long)|uniprotkb:GBAA_2007(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812187|imex:IM-13779-1602	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000116918.15(gene)|ensembl:ENST00000366639.9(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030154""(cell differentiation)|rcsb pdb:3QB5|go:""GO:0030422""(siRNA processing)|go:""GO:0031687""(A2A adenosine receptor binding)|go:""GO:0035194""(regulatory ncRNA-mediated post-transcriptional gene silencing)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:1902555""(endoribonuclease complex)|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|interpro:IPR016069(Translin, C-terminal)|interpro:IPR036081|mint:Q99598|rcsb pdb:3PJA|reactome:R-HSA-426486|uniprotkb:A0A024R3V8(uniprot-removed-ac)|dip:DIP-29463N|refseq:NP_005990.1|panther:PTHR10741(orthology-group)"	interpro:IPR007061(Protein of unknown function DUF664)|refseq:WP_001018093.1|interpro:IPR034660	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606	rogid:bZqpMYbUnAit6yydnyWCxzO6WG41392	intact-crc:1A5C2A67F0B665F5|rigid:+nYXPC0LxQvq6kVoJ0/DhVGB6U4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99816	uniprotkb:A0A6L7H1C2	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968.3	intact:EBI-2809848|uniprotkb:Q6KMV0|uniprotkb:Q6HTL0|uniprotkb:E9QWV5|uniprotkb:E9QWV6|uniprotkb:A0A2P0HIT1|uniprotkb:Q81M57	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:a0a6l7h1c2_bacan(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:GBAA_4397(locus name)|uniprotkb:Recombination protein N(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812194|imex:IM-13779-1601	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006283.1|dip:DIP-31809N|panther:PTHR23306(orthology-group)|rcsb pdb:1M4P|ensembl:ENSG00000074319.13(gene)|ensembl:ENST00000251968.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000813""(ESCRT I complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006858""(extracellular transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0019076""(viral release from host cell)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0036211""(protein modification process)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043405""(regulation of MAP kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046755""(viral budding)|go:""GO:0046790""(virion binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0051301""(cell division)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090148""(membrane fission)|go:""GO:0090543""(Flemming body)|go:""GO:0097352""(autophagosome maturation)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903551""(regulation of extracellular exosome assembly)|go:""GO:1903774""(positive regulation of viral budding via host ESCRT complex)|go:""GO:1990182""(exosomal secretion)|go:""GO:2000397""(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|interpro:IPR052070|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|rcsb pdb:7NLC|rcsb pdb:7ZLX|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|refseq:WP_000947756.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:aXVFQ2/u7+QhLnMBoqc0Kc6RtX01392	intact-crc:16F933B21714386F|rigid:wYaGAHynq6QGNf77rD2k+T8ly1Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15654	uniprotkb:A0A6L8P706	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|uniprotkb:F2ZC07|uniprotkb:F2ZC08|ensembl:ENSP00000200457.4	intact:EBI-2812225|uniprotkb:Q6I0N2|uniprotkb:Q6KUJ1|uniprotkb:E9QW18|uniprotkb:E9QW19|uniprotkb:A0A2P0HCA8|uniprotkb:Q81SF2	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:a0a6l8p706_bacan(display_long)|uniprotkb:GBAA_1706(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812230|imex:IM-13779-1606	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003293.2|dip:DIP-34466N|ensembl:ENSG00000087077.14(gene)|ensembl:ENST00000200457.9(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003723""(RNA binding)|go:""GO:0005149""(interleukin-1 receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0019900""(kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0043009""(chordate embryonic development)|go:""GO:0046872""(metal ion binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|panther:PTHR24212(orthology-group)"	"interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009288""(bacterial-type flagellum)|refseq:WP_001222388.1|interpro:IPR042187|interpro:IPR046358"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:E4keB86WCxgOoOrZylw1M6OqCFM1392	intact-crc:E9847C23E748C106|rigid:Icoqv/k/TW/WeceWJ5bpkBpjvKg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NDV7	uniprotkb:Q81TZ1	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	intact:EBI-2812253|uniprotkb:Q6KW11|uniprotkb:E9QRG3	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	psi-mi:q81tz1_bacan(display_long)|uniprotkb:GBAA_1107(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812250|imex:IM-13779-1607	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	rogid:uTIQYuSWBxYTOh5vNuOOmn6mtdo1392	intact-crc:86F1380B1F1E65CA|rigid:F+ltf6chIgZJdjtMFG07nyPr1MI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NDV7	uniprotkb:A0A6L8PJK6	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	intact:EBI-2812240|uniprotkb:Q6KX38|uniprotkb:Q6I3C1|uniprotkb:E9QUC2|uniprotkb:E9QUC3|uniprotkb:Q81V38|uniprotkb:A0A0F7RJ14	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	psi-mi:a0a6l8pjk6_bacan(display_long)|uniprotkb:rbsK(gene name)|psi-mi:rbsK(display_short)|uniprotkb:GBAA_0665(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812237|imex:IM-13779-1605	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR002173(Carbohydrate/puine kinase, PfkB, conserved site)|interpro:IPR011877(Ribokinase, bacterial)|interpro:IPR002139(Ribokinase)|interpro:IPR029056|go:""GO:0004747""(ribokinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019303""(D-ribose catabolic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_001132852.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	rogid:bCT50FjU1Cr3U/oOrt5sbgTy9Ts1392	intact-crc:40146B77A24069ED|rigid:Yo0QS15OfcYRAlvFvD9FsOdZZiI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15643	uniprotkb:A0A348A041	intact:EBI-1047183|uniprotkb:O14689|uniprotkb:O15154|uniprotkb:O95949|uniprotkb:B2RUT2|uniprotkb:Q6MZL5|ensembl:ENSP00000267622.4	intact:EBI-2812214|uniprotkb:Q6KWE3|uniprotkb:E9R2C7|uniprotkb:Q81UC9	psi-mi:tripb_human(display_long)|uniprotkb:Golgi-associated microtubule-binding protein 210(gene name synonym)|uniprotkb:Clonal evolution-related gene on chromosome 14 protein(gene name synonym)|uniprotkb:Trip230(gene name synonym)|uniprotkb:TRIP11(gene name)|psi-mi:TRIP11(display_short)|uniprotkb:CEV14(gene name synonym)	psi-mi:a0a348a041_bacan(display_long)|uniprotkb:GBAA_0949(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812218|imex:IM-13779-1604	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100815.12(gene)|ensembl:ENST00000267622.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002079""(inner acrosomal membrane)|go:""GO:0002081""(outer acrosomal membrane)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003413""(chondrocyte differentiation involved in endochondral bone morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0030133""(transport vesicle)|go:""GO:0031267""(small GTPase binding)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0051216""(cartilage development)|go:""GO:0060122""(inner ear receptor cell stereocilium organization)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0090161""(Golgi ribbon formation)|go:""GO:0099041""(vesicle tethering to Golgi)|interpro:IPR000237(GRIP)|mint:Q15643|reactome:R-HSA-5620924|reactome:R-HSA-6811438|reactome:R-HSA-9703465|refseq:NP_004230.2|dip:DIP-40357N|efo:""Orphanet:166272""|efo:""Orphanet:93299""|panther:PTHR18921(orthology-group)"	refseq:WP_000013670.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M/XOdT1ZPDaQqMuBXsAB5p6N9LY9606	rogid:HACbCzsVWs9UlcTV2aFEjTeNEbQ1392	intact-crc:A689B3A2B6548221|rigid:M690K6T9i1z0Iu8nM2Zvmjm92nk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HHX2	uniprotkb:P14868	intact:EBI-2812285|uniprotkb:Q6KUB0|uniprotkb:Q6I0E0|uniprotkb:E9QSI8|uniprotkb:E9QSI9|uniprotkb:Q81S59|uniprotkb:A0A0F7RKM4	intact:EBI-358730|uniprotkb:Q2TNI3|uniprotkb:Q32Q69|uniprotkb:Q53HV4|uniprotkb:Q53YC5|uniprotkb:Q9BW52|uniprotkb:A8K3J2|uniprotkb:D3DP77|ensembl:ENSP00000264161.4|uniprotkb:Q68CR9	psi-mi:a0a6l7hhx2_bacan(display_long)|uniprotkb:GBAA_1815(locus name)	psi-mi:sydc_human(display_long)|uniprotkb:DARS1(gene name)|psi-mi:DARS1(display_short)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 40 protein(gene name synonym)|uniprotkb:DARS(gene name synonym)|uniprotkb:PIG40(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812282|imex:IM-13779-1612	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025450|go:""GO:0016020""(membrane)|refseq:WP_000789548.1"	"ensembl:ENSG00000115866.11(gene)|ensembl:ENST00000264161.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004046""(aminoacylase activity)|go:""GO:0004815""(aspartate-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0006422""(aspartyl-tRNA aminoacylation)|go:""GO:0016020""(membrane)|go:""GO:0017101""(aminoacyl-tRNA synthetase multienzyme complex)|go:""GO:0045202""(synapse)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004523(Aspartyl-tRNA synthetase, class IIb, archea/euk type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR045864|mint:P14868|rcsb pdb:4J15|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-9856649|refseq:NP_001280241.1|refseq:NP_001340.2|efo:""Orphanet:363412""|panther:PTHR43450(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:g0iSNc7Mh4tgNaBj+nHYsEjH5sY1392	rogid:Yzpil/THkSHGR/ixVyQbV3RZz/E9606	intact-crc:E5EF48C2DAE9CFB9|rigid:gNpRPS6v7RBKi3IDLhkf0O8JZK8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10587	uniprotkb:A0A6H3A8V4	intact:EBI-2796967|uniprotkb:B0QYS8|ensembl:ENSP00000266304.4|uniprotkb:Q8IU94|uniprotkb:Q15729|uniprotkb:B2RC22|uniprotkb:Q96TG4|uniprotkb:Q7Z3J7	intact:EBI-2810133|uniprotkb:A0A1J9WG58|uniprotkb:Q6KWL8|uniprotkb:Q6I2T9|uniprotkb:E9RC14|uniprotkb:E9RC15|uniprotkb:Q81UL0|uniprotkb:A0A2B8HWP9	psi-mi:tef_human(display_long)|uniprotkb:KIAA1655(gene name synonym)|uniprotkb:TEF(gene name)|psi-mi:TEF(display_short)	psi-mi:a0a6h3a8v4_bacan(display_long)|uniprotkb:sasP1(gene name)|psi-mi:sasP1(display_short)|uniprotkb:GBAA_0858(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812275|imex:IM-13779-1609	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138870.1|refseq:NP_003207.1|ensembl:ENSG00000167074.15(gene)|ensembl:ENST00000266304.9(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0048511""(rhythmic process)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|rcsb pdb:4U5T|panther:PTHR11988(orthology-group)"	"interpro:IPR001448(Small acid-soluble spore protein, alpha/beta type)|interpro:IPR018126|refseq:WP_000013338.1|interpro:IPR050847|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0006265""(DNA topological change)|interpro:IPR038300"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QXQh9ROTc0D9dcg3Qq76i3b/jFo9606	rogid:L0kfSsXpT8asMqUkNwqi8XwOx8s1392	intact-crc:C2E6EFBDDBF17F90|rigid:Tu7fDvQ3/sLR0grT784lYaqUWwM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UM00	uniprotkb:A0A2P0HLN8	intact:EBI-1051217|uniprotkb:O75545|uniprotkb:Q9BZS3|uniprotkb:Q9BZU8|uniprotkb:B2REA0|uniprotkb:J9JIE6|ensembl:ENSP00000480514.1	intact:EBI-2810906	psi-mi:tmco1_human(display_long)|uniprotkb:Transmembrane and coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:Xenogeneic cross-immune protein PCIA3(gene name synonym)|uniprotkb:Transmembrane and coiled-coil domains protein 4(gene name synonym)|uniprotkb:TMCO1(gene name)|psi-mi:TMCO1(display_short)|uniprotkb:PNAS-10(orf name)|uniprotkb:PNAS-136(orf name)|uniprotkb:UNQ151/PRO177(orf name)|uniprotkb:TMCC4(gene name synonym)|uniprotkb:GEL complex subunit TMCO1(gene name synonym)	psi-mi:a0a2p0hln8_bacan(display_long)|uniprotkb:spo0J(gene name)|psi-mi:spo0J(display_short)|uniprotkb:BA_5729(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812261|imex:IM-13779-1608	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143183.18(gene)|ensembl:ENST00000612311.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001503""(ossification)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006983""(ER overload response)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0043022""(ribosome binding)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0160063""(multi-pass transmembrane protein insertion into ER membrane)|go:""GO:0160064""(multi-pass translocon complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008559(Protein of unknown function DUF841, eukaryotic)|mint:Q9UM00|rcsb pdb:6W6L|refseq:NP_061899.2|efo:""Orphanet:1394""|panther:PTHR20917(orthology-group)"	"interpro:IPR050336|interpro:IPR003115(ParB-like nuclease)|interpro:IPR004437(ParB-like partition protein)|interpro:IPR036086|go:""GO:0003677""(DNA binding)|go:""GO:0005694""(chromosome)|go:""GO:0007059""(chromosome segregation)|go:""GO:0045881""(positive regulation of sporulation resulting in formation of a cellular spore)|uniprotkb:A0A2K1VHE8(uniprot-removed-ac)|interpro:IPR041468|refseq:NP_847874.2|refseq:WP_001051841.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AGRI6UgUEOjrVCi0laVQPtfaHRU9606	rogid:yZl0oXOncYOEs5/ejxEfcSQuNoE1392	intact-crc:28CAE9F86907ABE6|rigid:lf2voEIvCIKvLCUXkA56J/M2MIA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H9C3	uniprotkb:Q9UNK0	intact:EBI-2812297|uniprotkb:Q6KK92|uniprotkb:Q6HQX4|uniprotkb:E9R1I9|uniprotkb:E9R1J0|uniprotkb:Q81X37|uniprotkb:A0A1Q4LY85	intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255.2	psi-mi:a0a6l7h9c3_bacan(display_long)|uniprotkb:GBAA_5406(locus name)	psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812294|imex:IM-13779-1610	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|refseq:WP_001099975.1|interpro:IPR036388|interpro:IPR036390"	"refseq:NP_004844.1|ensembl:ENSG00000170310.15(gene)|ensembl:ENST00000306357.9(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0012505""(endomembrane system)|go:""GO:0019869""(chloride channel inhibitor activity)|go:""GO:0019905""(syntaxin binding)|go:""GO:0031201""(SNARE complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048278""(vesicle docking)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|interpro:IPR045242|mint:Q9UNK0|dip:DIP-47274N|panther:PTHR19957(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:RF415biCLiP0aJnqIsNwQXl5DRw1392	rogid:jdsUOdy99aWRb94ndPtawff7z/o9606	intact-crc:B16DFD7EF791BBB5|rigid:vNZPPloIXNbpqXgm+Q9tWxFWd7E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10587	uniprotkb:A0A6L7H2M3	intact:EBI-2796967|uniprotkb:B0QYS8|ensembl:ENSP00000266304.4|uniprotkb:Q8IU94|uniprotkb:Q15729|uniprotkb:B2RC22|uniprotkb:Q96TG4|uniprotkb:Q7Z3J7	intact:EBI-2812033	psi-mi:tef_human(display_long)|uniprotkb:KIAA1655(gene name synonym)|uniprotkb:TEF(gene name)|psi-mi:TEF(display_short)	psi-mi:a0a6l7h2m3_bacan(display_long)|uniprotkb:BA_3473(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812268|imex:IM-13779-1611	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138870.1|refseq:NP_003207.1|ensembl:ENSG00000167074.15(gene)|ensembl:ENST00000266304.9(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0048511""(rhythmic process)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|rcsb pdb:4U5T|panther:PTHR11988(orthology-group)"	"interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|refseq:NP_845755.2|interpro:IPR050237|go:""GO:0005524""(ATP binding)|go:""GO:0016877""(ligase activity, forming carbon-sulfur bonds)|uniprotkb:A0A0F7RG28(uniprot-removed-ac)|interpro:IPR045851"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QXQh9ROTc0D9dcg3Qq76i3b/jFo9606	rogid:tVv/bFqWNowqNLZ+P/5QYxKMrgE1392	intact-crc:1D9DF87483C5A079|rigid:i97mCPIer0MgEdUrMlh6Ilov848	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00560	uniprotkb:Q81KT8	intact:EBI-727004|uniprotkb:O43391|uniprotkb:O00173|uniprotkb:Q14CP2|ensembl:ENSP00000260130.4|ensembl:ENSP00000411771.2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812332|imex:IM-13779-1614	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137575.12(gene)|ensembl:ENST00000260130.9(transcript)|ensembl:ENST00000413219.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0005109""(frizzled binding)|go:""GO:0005137""(interleukin-5 receptor binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005895""(interleukin-5 receptor complex)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016020""(membrane)|go:""GO:0019838""(growth factor binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042043""(neurexin family protein binding)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045545""(syndecan binding)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0098793""(presynapse)|go:""GO:0099054""(presynapse assembly)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051230|mint:O00560|rcsb pdb:1N99|rcsb pdb:1NTE|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|rcsb pdb:7FSG|rcsb pdb:7FSH|rcsb pdb:7FSI|rcsb pdb:7FSJ|rcsb pdb:7FSK|rcsb pdb:7FSL|rcsb pdb:7FT5|rcsb pdb:7FSM|rcsb pdb:7FSN|rcsb pdb:7FSO|rcsb pdb:7FSP|rcsb pdb:7FSQ|rcsb pdb:7FSR|rcsb pdb:7FSS|rcsb pdb:7FST|rcsb pdb:7FSU|rcsb pdb:7FSV|rcsb pdb:7FSW|rcsb pdb:7FSX|rcsb pdb:7FSY|rcsb pdb:7FSZ|rcsb pdb:7FT0|rcsb pdb:7FT1|rcsb pdb:7FT2|rcsb pdb:7FT3|rcsb pdb:7FT4|rcsb pdb:7FT6|rcsb pdb:7FT7|rcsb pdb:7FT8|rcsb pdb:7FT9|rcsb pdb:7FTA|rcsb pdb:7FTB|rcsb pdb:7FTC|rcsb pdb:7FTD|rcsb pdb:8AAI|rcsb pdb:8AAK|rcsb pdb:8AAO|rcsb pdb:8AAP|rcsb pdb:8BLU|rcsb pdb:8BLV|rcsb pdb:8HCK|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-6798695|refseq:NP_001007068.1|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|dip:DIP-42705N|panther:PTHR12345(orthology-group)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	intact-crc:F3C60BF1692A6E0C|rigid:hfW21fjQ23xbuDyFoZ85QOHNi3I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81NB9	uniprotkb:P42226	intact:EBI-2812309|uniprotkb:Q6KQM6|uniprotkb:Q6HWH5|uniprotkb:E9R427|uniprotkb:E9R428|uniprotkb:A0A2P0HGL6	intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134.3|ensembl:ENSP00000401486.3|ensembl:ENSP00000438451.2|ensembl:ENSP00000450732.2|ensembl:ENSP00000450747.2|ensembl:ENSP00000451074.2|ensembl:ENSP00000451742.1|ensembl:ENSP00000452203.2|ensembl:ENSP00000452394.2|ensembl:ENSP00000519638.1|ensembl:ENSP00000519640.1	psi-mi:q81nb9_bacan(display_long)|uniprotkb:GBAA_3291(locus name)	psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812306|imex:IM-13779-1615	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003122(Chemotaxis methyl-accepting receptor, ligand-binding)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR033479|interpro:IPR029151|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)"	"panther:PTHR11801(orthology-group)|dip:DIP-39855N|efo:""Orphanet:2126""|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|ensembl:ENSG00000166888.13(gene)|ensembl:ENST00000300134.8(transcript)|ensembl:ENST00000454075.7(transcript)|ensembl:ENST00000543873.6(transcript)|ensembl:ENST00000553275.2(transcript)|ensembl:ENST00000553397.6(transcript)|ensembl:ENST00000553499.6(transcript)|ensembl:ENST00000555849.6(transcript)|ensembl:ENST00000556155.5(transcript)|ensembl:ENST00000557635.6(transcript)|ensembl:ENST00000714371.1(transcript)|ensembl:ENST00000714373.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0002296""(T-helper 1 cell lineage commitment)|go:""GO:0002829""(negative regulation of type 2 immune response)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006952""(defense response)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0033598""(mammary gland epithelial cell proliferation)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048289""(isotype switching to IgE isotypes)|go:""GO:0048295""(positive regulation of isotype switching to IgE isotypes)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0060443""(mammary gland morphogenesis)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070666""(regulation of mast cell proliferation)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1902170""(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|interpro:IPR048988|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:9BIG|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_001171551.1|refseq:NP_003144.3|refseq:XP_006719638.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/14	rogid:T8+w33pRMsereboSV5Xh/bY3EqQ1392	rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606	intact-crc:5DF856D23778C38B|rigid:UwVNP2X3O2CdEKoQevEEj9C+0gU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2G9	uniprotkb:A0A6L7HA67	intact:EBI-2812339|uniprotkb:A8K8P2|uniprotkb:Q8TEM0|uniprotkb:Q3KQX0|uniprotkb:O75257|uniprotkb:B3KWJ1|ensembl:ENSP00000354733.2|ensembl:ENSP00000477651.1|ensembl:ENSP00000488808.1	intact:EBI-2812348|uniprotkb:Q6I475|uniprotkb:Q6KXY1|uniprotkb:E9R3H0|uniprotkb:E9R3H1|uniprotkb:Q81ZC9|uniprotkb:A0A0F7RI49	psi-mi:sbno2_human(display_long)|uniprotkb:SBNO2(gene name)|psi-mi:SBNO2(display_short)|uniprotkb:KIAA0963(gene name synonym)	psi-mi:a0a6l7ha67_bacan(display_long)|uniprotkb:GBAA_0340(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812353|imex:IM-13779-1617	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001093592.1|refseq:NP_055778.2|ensembl:ENSG00000064932.16(gene)|ensembl:ENSG00000278788.4(gene)|ensembl:ENST00000361757.8(transcript)|ensembl:ENST00000612198.3(transcript)|ensembl:ENST00000631948.1(transcript)|go:""GO:0002281""(macrophage activation involved in immune response)|go:""GO:0005634""(nucleus)|go:""GO:0030282""(bone mineralization)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0042393""(histone binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0061430""(bone trabecula morphogenesis)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071348""(cellular response to interleukin-11)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0072675""(osteoclast fusion)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR026741|interpro:IPR026937|interpro:IPR027417|interpro:IPR039187|panther:PTHR12706(orthology-group)"	refseq:WP_000972836.1|interpro:IPR036390	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iPkqlBv3rJUTdMyX35ksXpOFutU9606	rogid:rzFKPdbWxl2+C6+7eh5l11tO6Qs1392	intact-crc:C9F26028A819CD39|rigid:X2MWpgRUDJF3alPd3oHP6orj4CA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P18583	uniprotkb:Q81S14	intact:EBI-1053513|uniprotkb:O14487|uniprotkb:O95981|uniprotkb:Q14120|uniprotkb:Q9H7B1|uniprotkb:Q9P070|uniprotkb:Q9P072|uniprotkb:Q9UKP9|uniprotkb:Q9UPY0|uniprotkb:D3DSF5|uniprotkb:D3DSF6|uniprotkb:E7ETE8|uniprotkb:E7EU67|uniprotkb:E7EVW3|uniprotkb:E9PFQ2|uniprotkb:Q6PKE0|intact:EBI-28988950|ensembl:ENSP00000348984.4	intact:EBI-2811794|uniprotkb:Q6I094|uniprotkb:Q6KU68	psi-mi:son_human(display_long)|uniprotkb:SON3(gene name synonym)|uniprotkb:Negative regulatory element-binding protein(gene name synonym)|uniprotkb:Protein DBP-5(gene name synonym)|uniprotkb:Bax antagonist selected in saccharomyces 1(gene name synonym)|uniprotkb:SON(gene name)|psi-mi:SON(display_short)|uniprotkb:C21orf50(gene name synonym)|uniprotkb:DBP5(gene name synonym)|uniprotkb:KIAA1019(gene name synonym)|uniprotkb:NREBP(gene name synonym)|uniprotkb:HSPC310(orf name)|uniprotkb:HSPC312(orf name)	psi-mi:mtad_bacan(display_long)|uniprotkb:mtaD(gene name)|psi-mi:mtaD(display_short)|uniprotkb:BA_1865(locus name)|uniprotkb:GBAA_1865(locus name)|uniprotkb:BAS1729(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812318|imex:IM-13779-1613	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:500150""|dip:DIP-42289N|ensembl:ENSG00000159140.23(gene)|ensembl:ENST00000356577.10(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0051726""(regulation of cell cycle)|interpro:IPR000467(D111/G-patch)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032922|interpro:IPR036322|mint:P18583|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DYN|refseq:NP_001278340.1|refseq:NP_001278341.1|refseq:NP_115571.2|refseq:NP_620305.2|panther:PTHR46528(orthology-group)"	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR023512|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR050287|go:""GO:0046872""(metal ion binding)|go:""GO:0050270""(S-adenosylhomocysteine deaminase activity)|go:""GO:0090614""(5'-methylthioadenosine deaminase activity)|interpro:IPR032466|refseq:NP_844282.1|refseq:YP_027994.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:XHPM2q25vXRqEK7eQpWvJ6Uzc3U9606	rogid:TDYnZJrYplZEtZNuGj+DQVH3gl81392	intact-crc:B640D4D73B9FB131|rigid:4pSvazzsAdiSoVNB9Kg8sx8yhok	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P18583	uniprotkb:A0A6L7H1G2	intact:EBI-1053513|uniprotkb:O14487|uniprotkb:O95981|uniprotkb:Q14120|uniprotkb:Q9H7B1|uniprotkb:Q9P070|uniprotkb:Q9P072|uniprotkb:Q9UKP9|uniprotkb:Q9UPY0|uniprotkb:D3DSF5|uniprotkb:D3DSF6|uniprotkb:E7ETE8|uniprotkb:E7EU67|uniprotkb:E7EVW3|uniprotkb:E9PFQ2|uniprotkb:Q6PKE0|intact:EBI-28988950|ensembl:ENSP00000348984.4	intact:EBI-2809927	psi-mi:son_human(display_long)|uniprotkb:SON3(gene name synonym)|uniprotkb:Negative regulatory element-binding protein(gene name synonym)|uniprotkb:Protein DBP-5(gene name synonym)|uniprotkb:Bax antagonist selected in saccharomyces 1(gene name synonym)|uniprotkb:SON(gene name)|psi-mi:SON(display_short)|uniprotkb:C21orf50(gene name synonym)|uniprotkb:DBP5(gene name synonym)|uniprotkb:KIAA1019(gene name synonym)|uniprotkb:NREBP(gene name synonym)|uniprotkb:HSPC310(orf name)|uniprotkb:HSPC312(orf name)	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812325|imex:IM-13779-1616	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:500150""|dip:DIP-42289N|ensembl:ENSG00000159140.23(gene)|ensembl:ENST00000356577.10(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0051726""(regulation of cell cycle)|interpro:IPR000467(D111/G-patch)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032922|interpro:IPR036322|mint:P18583|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DYN|refseq:NP_001278340.1|refseq:NP_001278341.1|refseq:NP_115571.2|refseq:NP_620305.2|panther:PTHR46528(orthology-group)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:XHPM2q25vXRqEK7eQpWvJ6Uzc3U9606	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	intact-crc:DEDEAEE2A5A4911F|rigid:MtQbOuAWn0ne6lUiQifIjgl626k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P0K7	uniprotkb:A0A2P0HDF0	intact:EBI-1023749|uniprotkb:Q6V1W9|uniprotkb:Q7Z5I4|uniprotkb:Q7Z733|uniprotkb:Q9P2L2|uniprotkb:Q9Y3T5|uniprotkb:E9PED3|intact:EBI-2555698|ensembl:ENSP00000265109.3|ensembl:ENSP00000388725.2|ensembl:ENSP00000422942.1	intact:EBI-2812392	psi-mi:rai14_human(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:RAI14(gene name)|psi-mi:RAI14(display_short)|uniprotkb:KIAA1334(gene name synonym)|uniprotkb:NORPEG(gene name synonym)	psi-mi:a0a2p0hdf0_bacan(display_long)|uniprotkb:BA_2121(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812397|imex:IM-13779-1621	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138992.1|refseq:NP_001138993.1|refseq:NP_001138994.1|refseq:NP_001138995.1|refseq:NP_001138997.1|refseq:NP_056392.2|refseq:XP_011512319.1|refseq:XP_011512320.1|refseq:XP_011512321.1|refseq:XP_011512322.1|refseq:XP_011512323.1|refseq:XP_011512324.1|refseq:XP_006714532.1|refseq:XP_016864824.1|ensembl:ENSG00000039560.14(gene)|ensembl:ENST00000265109.8(transcript)|ensembl:ENST00000428746.6(transcript)|ensembl:ENST00000503673.5(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030154""(cell differentiation)|go:""GO:0070161""(anchoring junction)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR042420|mint:Q9P0K7|panther:PTHR24129(orthology-group)"	interpro:IPR002881(Protein of unknown function DUF58)|refseq:NP_844519.2|refseq:WP_000831661.1|uniprotkb:Q81RC8(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:m5hQYx6HEi9QEAey1UiNpeAp6tw9606	rogid:P3iPDTKUbo0S8xT8slTyKxlgSqc1392	intact-crc:EBBFF64B0DD43A3E|rigid:MaJRiSdd0F1DgD95XashTC5wZXs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NVB0	uniprotkb:P49796	intact:EBI-2811493|uniprotkb:Q6KWL2|uniprotkb:Q6I2T1|uniprotkb:E9R8N8|uniprotkb:E9R8N9|uniprotkb:Q81UK2|uniprotkb:A0A0F7RLK2	intact:EBI-2107809|uniprotkb:A6NHA0|uniprotkb:Q8NFN6|uniprotkb:Q8WXA0|uniprotkb:Q5VXC1|uniprotkb:Q5VZ05|uniprotkb:Q6ZRM5|uniprotkb:Q8IUQ1|uniprotkb:Q8NC47|uniprotkb:Q8NFN4|uniprotkb:Q8NFN5|uniprotkb:Q8TD59|uniprotkb:Q8TD68|uniprotkb:B3KUB2|uniprotkb:A8K0V1|uniprotkb:Q5VXB8|uniprotkb:Q5VZ06|uniprotkb:Q8WV02|ensembl:ENSP00000259406.7|ensembl:ENSP00000363255.2	psi-mi:a0a6l8nvb0_bacan(display_long)|uniprotkb:alsS(gene name)|psi-mi:alsS(display_short)|uniprotkb:GBAA_0866(locus name)	psi-mi:rgs3_human(display_long)|uniprotkb:RGS3(gene name)|psi-mi:RGS3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2812385|imex:IM-13779-1619	author score:3|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012782(Acetolactate synthase, catabolic)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR029035|interpro:IPR029061|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003984""(acetolactate synthase activity)|go:""GO:0005948""(acetolactate synthase complex)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0034077""(butanediol metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_000103511.1|interpro:IPR045229"	"refseq:NP_001269851.1|refseq:NP_001269852.1|refseq:XP_006717282.1|refseq:NP_060260.3|refseq:NP_570613.2|refseq:NP_652759.3|refseq:NP_001263189.1|refseq:NP_001263191.1|refseq:NP_602299.1|refseq:NP_652760.2|panther:PTHR46848(orthology-group)|refseq:NP_001263190.1|refseq:XP_006717289.1|refseq:XP_006717293.1|refseq:XP_011517198.1|refseq:XP_011517199.1|refseq:XP_011517200.1|refseq:XP_011517202.1|refseq:XP_011517203.1|refseq:XP_016870494.1|refseq:XP_016870495.1|ensembl:ENSG00000138835.24(gene)|ensembl:ENST00000350696.9(transcript)|ensembl:ENST00000374140.6(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0009968""(negative regulation of signal transduction)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR034951|interpro:IPR035892|interpro:IPR036034|interpro:IPR036305|interpro:IPR044926|mint:P49796|rcsb pdb:2F5Y|rcsb pdb:2OJ4|rcsb pdb:3FBK|reactome:R-HSA-416476|reactome:R-HSA-418594"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rRCMmJc9HuwjVl3UsPYv6jvntSI1392	rogid:Xe1DKEKnIxEZ6X2F97smZSW2FrA9606	intact-crc:01145FA732AD6B15|rigid:5MpMGR/vos4hujv8++szmqbqd5I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P0A6H1	uniprotkb:Q16740-PRO_0000005516	intact:EBI-547386|uniprotkb:P33138|uniprotkb:Q2MBY8	intact:EBI-25815820	psi-mi:clpx_ecoli(display_long)|uniprotkb:clpX(gene name)|psi-mi:clpX(display_short)|uniprotkb:lopC(gene name synonym)|uniprotkb:b0438(locus name)|uniprotkb:JW0428(locus name)|uniprotkb:ATP-dependent unfoldase ClpX(gene name synonym)	psi-mi:q16740-pro_0000005516(display_long)|uniprotkb:CLPP(gene name)|psi-mi:CLPP(display_short)|uniprotkb:Endopeptidase Clp(gene name synonym)|uniprotkb:Caseinolytic mitochondrial matrix peptidase proteolytic subunit(gene name synonym)	"psi-mi:""MI:0435""(protease assay)"	Kang et al. (2004)	pubmed:15522782|imex:IM-28396	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0570""(protein cleavage)"	"psi-mi:""MI:0486""(UniProt)"	intact:EBI-25828468|imex:IM-28396-7	intact-miscore:0.44	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:1343""(enzyme regulator)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_414972.1|refseq:WP_000130305.1|dip:DIP-35907N|go:""GO:0002020""(protease binding)|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009368""(endopeptidase Clp complex)|go:""GO:0009376""(HslUV protease complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030164""(protein denaturation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043335""(protein unfolding)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051301""(cell division)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|interpro:IPR038366|interpro:IPR046425|interpro:IPR050052|rcsb pdb:1OVX|rcsb pdb:2DS5|rcsb pdb:2DS6|rcsb pdb:2DS7|rcsb pdb:2DS8|rcsb pdb:3HTE|rcsb pdb:3HWS|rcsb pdb:4I34|rcsb pdb:4I4L|rcsb pdb:4I5O|rcsb pdb:4I63|rcsb pdb:4I81|rcsb pdb:4I9K|rcsb pdb:6PO1|rcsb pdb:6PO3|rcsb pdb:6POD|rcsb pdb:6POS|rcsb pdb:6PP5|rcsb pdb:6PP6|rcsb pdb:6PP7|rcsb pdb:6PP8|rcsb pdb:6PPE|rcsb pdb:6WR2|rcsb pdb:6WRF|rcsb pdb:6WSG|rcsb pdb:8E7V|rcsb pdb:8E8Q|rcsb pdb:8E91|rcsb pdb:8ET3|rcsb pdb:8V9R|rcsb pdb:9C87|rcsb pdb:9C88|panther:PTHR48102(orthology-group)"	intact:EBI-1056029(chain-parent)	-	-	chain-seq-start:57|chain-seq-end:277	figure legend:Fig. 6B,|comment:Removal of the 28 C-terminal amino-acid resiudes of CLPP increased reaction rate, which has been inferred to suggest increased the interaction with CLPP.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/18	2024/11/14	rogid:6//qYAydC2CE8MbKznReK0+ywDk83333	rogid:NI9vS/tAKFh0iOSRNzRVlHUxUbc9606	intact-crc:85C180898DF0A19F|rigid:dRH6bmKpiSj8tex8k2g9ziPY8F4	false	-	sufficient binding region:1-193	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P07355	uniprotkb:B7UM99	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Munera et al. (2012)	pubmed:22587461|imex:IM-28348	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25829597|imex:IM-28348-11	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	-	-	-	"figure legend:fig. 3 suppl.fig.2|comment:""\""HeLa cells ectopically expressing GFP–AnxA2 were infected for 2 h with wild-type E2348/69 (E69) and E69Δtir strains. E69ΔescN was used as a control. Immunofluorescence revealed that, whereas AnxA2 was recruited to wild-type EPEC in 90–100% of examined cells, it was not recruited to the attachment sites of EPEC Δtir or ΔescN in any of the cells examined (Figure 3)\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/08	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:577F0C050814B216|rigid:cD21WBRPh9JdG5w8vzIXd8kgIyw	false	green fluorescent protein tag:?-?	mutation with no effect:474-474	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P07355	uniprotkb:B7UM99	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0809""(bimolecular fluorescence complementation)"	Munera et al. (2012)	pubmed:22587461|imex:IM-28348	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25829625|imex:IM-28348-13	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	-	-	-	figure legend:fig. 4a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2020/09/08	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:E62E6DDA49C10D6C|rigid:cD21WBRPh9JdG5w8vzIXd8kgIyw	false	n-venus:?-?	c-venus:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P07355	uniprotkb:Q7DB77	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0809""(bimolecular fluorescence complementation)"	Munera et al. (2012)	pubmed:22587461|imex:IM-28348	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25829633|imex:IM-28348-15	intact-miscore:0.53	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:fig. 4a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2020/09/08	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:96FC8AD1924EC0DE|rigid:084GbKM2AUbRbj2CCP0GSU1yGR4	false	n-venus:?-?	c-venus:?-?	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P07355	uniprotkb:Q7DB77	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	"psi-mi:""MI:0047""(far western blotting)"	Munera et al. (2012)	pubmed:22587461|imex:IM-28348	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25829641|imex:IM-28348-17	intact-miscore:0.53	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	-	-	-	figure legend:fig. 4b-5|comment:Specific interaction of AnxA2 with TirN and TirC showed that TirC of EHEC and C. rodentium interacted with AnxA2 more strongly than their corresponding TirN domains, which showed a reduced level of binding to AnxA2.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/08	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	intact-crc:F28C3ED8CB347F7C|rigid:084GbKM2AUbRbj2CCP0GSU1yGR4	false	ha tag:?-?|binding-associated region:191-339	his tag:?-?|binding-associated region:366-558	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P07355	uniprotkb:Q7BHL5	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-25829671	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:q7bhl5_citro(display_long)|uniprotkb:Secreted effector protein Tir(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Munera et al. (2012)	pubmed:22587461|imex:IM-28348	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:67825(Citrobacter rodentium)|taxid:67825(Citrobacter rodentium)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25829656|imex:IM-28348-27	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|refseq:WP_012907112.1|interpro:IPR037003|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|mint:Q7BHL5"	-	-	-	figure legend:fig. 5|comment:Specific interaction of AnxA2 with TirN and TirC showed that TirC of EHEC and C. rodentium interacted with AnxA2 more strongly than their corresponding TirN domains, which showed a reduced level of binding to AnxA2.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/08	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:AI4JzHLvzSiPX87ffIWCLk374I067825	intact-crc:D25449702B1111C1|rigid:jS2UV+UwPFY4XVwDsIxFyuKrQ3s	false	ha tag:?-?|binding-associated region:191-339	his tag:?-?|binding-associated region:367-547	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P07355	uniprotkb:B7UM99	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|ensembl:ENSP00000379342.3|ensembl:ENSP00000387545.3|ensembl:ENSP00000411352.2|ensembl:ENSP00000452858.2|ensembl:ENSP00000452895.2|ensembl:ENSP00000452981.2|ensembl:ENSP00000453694.2|ensembl:ENSP00000453859.2|ensembl:ENSP00000503447.1|ensembl:ENSP00000503757.1|ensembl:ENSP00000503855.1|ensembl:ENSP00000504035.1|ensembl:ENSP00000504164.1|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0047""(far western blotting)"	Munera et al. (2012)	pubmed:22587461|imex:IM-28348	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25829690|imex:IM-28348-19	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|ensembl:ENSG00000182718.18(gene)|ensembl:ENST00000396024.7(transcript)|ensembl:ENST00000421017.6(transcript)|ensembl:ENST00000451270.7(transcript)|ensembl:ENST00000557906.6(transcript)|ensembl:ENST00000558558.6(transcript)|ensembl:ENST00000559818.6(transcript)|ensembl:ENST00000559956.6(transcript)|ensembl:ENST00000560468.6(transcript)|ensembl:ENST00000677968.1(transcript)|ensembl:ENST00000678061.1(transcript)|ensembl:ENST00000678450.1(transcript)|ensembl:ENST00000678870.1(transcript)|ensembl:ENST00000679109.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0002020""(protease binding)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014823""(response to activity)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019834""(phospholipase A2 inhibitor activity)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0030496""(midbody)|go:""GO:0031340""(positive regulation of vesicle fusion)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032804""(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0036035""(osteoclast development)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042730""(fibrinolysis)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0044090""(positive regulation of vacuole organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905581""(positive regulation of low-density lipoprotein particle clearance)|go:""GO:1905597""(positive regulation of low-density lipoprotein particle receptor binding)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1905602""(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:1905686""(positive regulation of plasma membrane repair)|go:""GO:1990665""(AnxA2-p11 complex)|go:""GO:1990667""(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|rcsb pdb:7DTO|rcsb pdb:7EQ7|rcsb pdb:7NMI|rcsb pdb:7P70|rcsb pdb:7P71|rcsb pdb:7P72|rcsb pdb:7P73|rcsb pdb:7P74|rcsb pdb:7PC3|rcsb pdb:7PC4|rcsb pdb:7PC5|rcsb pdb:7PC7|rcsb pdb:7PC8|rcsb pdb:7PC9|rcsb pdb:7PCB|rcsb pdb:7QQL|rcsb pdb:7QQM|rcsb pdb:7QQN|rcsb pdb:7ZVN|rcsb pdb:7ZVX|rcsb pdb:8AEL|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|reactome:R-HSA-9860927|refseq:XP_016877579.1|refseq:XP_016877580.1|panther:PTHR10502(orthology-group)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	-	-	-	figure legend:fig. 5|comment:Specific interaction of AnxA2 with TirN and TirC showed that TirC of EHEC and C. rodentium interacted with AnxA2 more strongly than their corresponding TirN domains, which showed a reduced level of binding to AnxA2.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/08	2024/11/14	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:23C6884970403456|rigid:cD21WBRPh9JdG5w8vzIXd8kgIyw	false	ha tag:?-?|binding-associated region:191-339	his tag:?-?	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P49755	uniprotkb:Q8XAL7	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145.4	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Olsen et al. (2013)	pubmed:23434013|imex:IM-28340	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25828269|imex:IM-28340-1	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006818.3|ensembl:ENSG00000170348.9(gene)|ensembl:ENST00000303575.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0032732""(positive regulation of interleukin-1 production)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0035964""(COPI-coated vesicle budding)|go:""GO:0042470""(melanosome)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0048199""(vesicle targeting, to, from or within Golgi)|go:""GO:0048205""(COPI coating of Golgi vesicle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0070765""(gamma-secretase complex)|go:""GO:0106272""(protein localization to ERGIC)|go:""GO:0106273""(cytosol to ERGIC protein transport)|go:""GO:1902003""(regulation of amyloid-beta formation)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR22811(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	"figure legend:text|comment:""\""We identified 3 different human cDNA sequences (Tmp21, CD151, PAIP2) that may encode proteins that interact with NleF. Among these, we further studied Tmp21 (also named p23/p24d) as a putative NleF binding partner.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/09/08	2024/11/14	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:6E709A0D5714F34B|rigid:/KZhjMvasrKH0laA/0JgVWClhRw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P48509	uniprotkb:Q8XAL7	intact:EBI-10210332|uniprotkb:Q86U54|uniprotkb:Q14826|uniprotkb:E9PI15|uniprotkb:Q96TE3|uniprotkb:A8KAK8|ensembl:ENSP00000324101.4|ensembl:ENSP00000380565.3|ensembl:ENSP00000380566.1|ensembl:ENSP00000432385.1	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:cd151_human(display_long)|uniprotkb:CD151(gene name)|psi-mi:CD151(display_short)|uniprotkb:GP27(gene name synonym)|uniprotkb:Membrane glycoprotein SFA-1(gene name synonym)|uniprotkb:Platelet-endothelial tetraspan antigen 3(gene name synonym)|uniprotkb:TSPAN24(gene name synonym)|uniprotkb:Tetraspanin-24(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Olsen et al. (2013)	pubmed:23434013|imex:IM-28340	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25828283|imex:IM-28340-3	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR19282(orthology-group)|ensembl:ENSG00000177697.19(gene)|ensembl:ENST00000322008.9(transcript)|ensembl:ENST00000397420.9(transcript)|ensembl:ENST00000397421.5(transcript)|ensembl:ENST00000530726.5(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0042098""(T cell proliferation)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045807""(positive regulation of endocytosis)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P48509|reactome:R-HSA-2022090|reactome:R-HSA-446107|refseq:NP_001034579.1|refseq:NP_004348.2|refseq:NP_620598.1|refseq:NP_620599.1|efo:""Orphanet:300333"""	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	"figure legend:text|comment:""\""We identified 3 different human cDNA sequences (Tmp21, CD151, PAIP2) that may encode proteins that interact with NleF. Among these, we further studied Tmp21 (also named p23/p24d) as a putative NleF binding partner.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/09/08	2024/11/14	rogid:Cxlf8123VFoYdzJ5fh0jzkSaaL09606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:8A30B813ABD2FE86|rigid:yNoujhtVeTQG8goIiD97t3ebres	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9BPZ3	uniprotkb:Q8XAL7	intact:EBI-2957445|intact:EBI-28983240|uniprotkb:Q49A06|uniprotkb:Q9P0Q8|uniprotkb:Q9H0Y5|uniprotkb:B2RBI1|uniprotkb:D3DQC6|ensembl:ENSP00000265192.4|ensembl:ENSP00000378275.2|ensembl:ENSP00000422508.1	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:paip2_human(display_long)|uniprotkb:PAIP2(gene name)|psi-mi:PAIP2(display_short)|uniprotkb:PAIP2A(gene name synonym)|uniprotkb:HSPC218(orf name)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Olsen et al. (2013)	pubmed:23434013|imex:IM-28340	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25828288|imex:IM-28340-5	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001028284.1|refseq:NP_057564.3|refseq:XP_011541730.1|refseq:XP_016865011.1|refseq:XP_016865012.1|ensembl:ENSG00000120727.13(gene)|ensembl:ENST00000265192.9(transcript)|ensembl:ENST00000394795.6(transcript)|ensembl:ENST00000510080.1(transcript)|go:""GO:0000900""(mRNA regulatory element binding translation repressor activity)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006412""(translation)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007613""(memory)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030371""(translation repressor activity)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:1900271""(regulation of long-term synaptic potentiation)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR040396|mint:Q9BPZ3|rcsb pdb:1JGN|rcsb pdb:3KUS|rcsb pdb:3KUT|panther:PTHR13154(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	"figure legend:text|comment:""\""We identified 3 different human cDNA sequences (Tmp21, CD151, PAIP2) that may encode proteins that interact with NleF. Among these, we further studied Tmp21 (also named p23/p24d) as a putative NleF binding partner.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/09/08	2024/11/14	rogid:g8odIyznsg186nI0YTU30fzY+yQ9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:2623B5473D5A63EE|rigid:N0TSmR8RaYKvYoIn9RI31szXuOE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P49755	uniprotkb:Q8XAL7	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145.4	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Olsen et al. (2013)	pubmed:23434013|imex:IM-28340	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25828300|imex:IM-28340-7	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006818.3|ensembl:ENSG00000170348.9(gene)|ensembl:ENST00000303575.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0032732""(positive regulation of interleukin-1 production)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0035964""(COPI-coated vesicle budding)|go:""GO:0042470""(melanosome)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0048199""(vesicle targeting, to, from or within Golgi)|go:""GO:0048205""(COPI coating of Golgi vesicle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0070765""(gamma-secretase complex)|go:""GO:0106272""(protein localization to ERGIC)|go:""GO:0106273""(cytosol to ERGIC protein transport)|go:""GO:1902003""(regulation of amyloid-beta formation)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR22811(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	figure legend:fig.1a|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/09/08	2024/11/14	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:93F3A85AF578134A|rigid:/KZhjMvasrKH0laA/0JgVWClhRw	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P49755	uniprotkb:Q8XAL7	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145.4	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Olsen et al. (2013)	pubmed:23434013|imex:IM-28340	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25828337|imex:IM-28340-9	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006818.3|ensembl:ENSG00000170348.9(gene)|ensembl:ENST00000303575.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0032732""(positive regulation of interleukin-1 production)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0035964""(COPI-coated vesicle budding)|go:""GO:0042470""(melanosome)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0048199""(vesicle targeting, to, from or within Golgi)|go:""GO:0048205""(COPI coating of Golgi vesicle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0070765""(gamma-secretase complex)|go:""GO:0106272""(protein localization to ERGIC)|go:""GO:0106273""(cytosol to ERGIC protein transport)|go:""GO:1902003""(regulation of amyloid-beta formation)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR22811(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	"figure legend:fig.1b|comment:""\""By expressing and purifying recombinant forms of NleF and Tmp21 in E. coli BL21(DE3)  and then using these proteins in pulldown assays, we confirmed that NleF and Tmp21 bind  directly in vitro (Fig. 1B).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/08	2024/11/14	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:5BE2F4CC7171CD38|rigid:/KZhjMvasrKH0laA/0JgVWClhRw	false	his tag:?-?	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P49755	uniprotkb:Q8XAL7	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145.4	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Olsen et al. (2013)	pubmed:23434013|imex:IM-28340	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25828379|imex:IM-28340-11	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006818.3|ensembl:ENSG00000170348.9(gene)|ensembl:ENST00000303575.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0032732""(positive regulation of interleukin-1 production)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0035964""(COPI-coated vesicle budding)|go:""GO:0042470""(melanosome)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0048199""(vesicle targeting, to, from or within Golgi)|go:""GO:0048205""(COPI coating of Golgi vesicle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0070765""(gamma-secretase complex)|go:""GO:0106272""(protein localization to ERGIC)|go:""GO:0106273""(cytosol to ERGIC protein transport)|go:""GO:1902003""(regulation of amyloid-beta formation)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR22811(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	"go:""GO:0048471""(perinuclear region of cytoplasm)"	-	-	figure legend:fig.1d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/08	2024/11/14	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:510C3A032FB84F54|rigid:/KZhjMvasrKH0laA/0JgVWClhRw	false	ha tag:?-?	flag tag:?-?	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P49755	uniprotkb:Q8XAL7	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145.4	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0809""(bimolecular fluorescence complementation)"	Olsen et al. (2013)	pubmed:23434013|imex:IM-28340	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25828427|imex:IM-28340-13	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006818.3|ensembl:ENSG00000170348.9(gene)|ensembl:ENST00000303575.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0032732""(positive regulation of interleukin-1 production)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0035964""(COPI-coated vesicle budding)|go:""GO:0042470""(melanosome)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0048199""(vesicle targeting, to, from or within Golgi)|go:""GO:0048205""(COPI coating of Golgi vesicle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0070765""(gamma-secretase complex)|go:""GO:0106272""(protein localization to ERGIC)|go:""GO:0106273""(cytosol to ERGIC protein transport)|go:""GO:1902003""(regulation of amyloid-beta formation)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR22811(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	figure legend:fig.2 b-d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/08	2024/11/14	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:F57E1F0249D32B94|rigid:/KZhjMvasrKH0laA/0JgVWClhRw	false	n-venus:?-?	c-venus:?-?|necessary binding region:66-84	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:Q8XAL7	uniprotkb:P49755	intact:EBI-10039292|uniprotkb:Q7AEM9	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145.4	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	"psi-mi:""MI:0809""(bimolecular fluorescence complementation)"	Olsen et al. (2013)	pubmed:23434013|imex:IM-28340	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25828438|imex:IM-28340-15	intact-miscore:0.63	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	"refseq:NP_006818.3|ensembl:ENSG00000170348.9(gene)|ensembl:ENST00000303575.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0032732""(positive regulation of interleukin-1 production)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0035964""(COPI-coated vesicle budding)|go:""GO:0042470""(melanosome)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0048199""(vesicle targeting, to, from or within Golgi)|go:""GO:0048205""(COPI coating of Golgi vesicle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0070765""(gamma-secretase complex)|go:""GO:0106272""(protein localization to ERGIC)|go:""GO:0106273""(cytosol to ERGIC protein transport)|go:""GO:1902003""(regulation of amyloid-beta formation)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR22811(orthology-group)"	-	-	-	figure legend:fig.2 b-d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2020/09/08	2024/11/14	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	intact-crc:D70E54BC465ACE4A|rigid:/KZhjMvasrKH0laA/0JgVWClhRw	false	n-venus:?-?	c-venus:?-?|necessary binding region:64-124	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P55211	uniprotkb:Q8XAL7	intact:EBI-516799|uniprotkb:O95348|uniprotkb:Q92852|uniprotkb:Q9BQ62|uniprotkb:Q9UEQ3|uniprotkb:Q9UIJ8|uniprotkb:Q53Y70|uniprotkb:Q5JRU9|uniprotkb:Q5UGI1|uniprotkb:B4E1A3|ensembl:ENSP00000330237.5	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:casp9_human(display_long)|uniprotkb:ICE-like apoptotic protease 6(gene name synonym)|uniprotkb:Apoptotic protease Mch-6(gene name synonym)|uniprotkb:Apoptotic protease-activating factor 3(gene name synonym)|uniprotkb:CASP9(gene name)|psi-mi:CASP9(display_short)|uniprotkb:MCH6(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Blasche et al. (2012)	pubmed:23516580|imex:IM-28332	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25825627|imex:IM-28332-1	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001264983.1|refseq:NP_001220.2|refseq:NP_127463.2|refseq:XP_005246071.1|ensembl:ENSG00000132906.18(gene)|ensembl:ENST00000333868.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001822""(kidney development)|go:""GO:0002931""(response to ischemia)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008233""(peptidase activity)|go:""GO:0008303""(caspase complex)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0016485""(protein processing)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030220""(platelet formation)|go:""GO:0032025""(response to cobalt ion)|go:""GO:0032355""(response to estradiol)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034349""(glial cell apoptotic process)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043293""(apoptosome)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044346""(fibroblast apoptotic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051604""(protein maturation)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0071887""(leukocyte apoptotic process)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR011600(Peptidase C14, caspase catalytic)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR042147|mint:P55211|rcsb pdb:1JXQ|rcsb pdb:1NW9|rcsb pdb:2AR9|rcsb pdb:3D9T|rcsb pdb:3V3K|rcsb pdb:3YGS|rcsb pdb:4RHW|rcsb pdb:5JUY|rcsb pdb:5WVC|rcsb pdb:5WVE|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-168638|reactome:R-HSA-198323|reactome:R-HSA-418889|reactome:R-HSA-5674400|reactome:R-HSA-9627069|panther:PTHR10454(orthology-group)|dip:DIP-27625N"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	figure legend:text|comment:In a systematic effort to elucidate the cellular targets of EHEC effector proteins, we identified caspase-9 as a binding partner of NleF. Caspase-9 was the predominant hit identified in screens of NleF against amino- and carboxy-terminally tagged yeast two-hybrid libraries|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2020/09/08	2024/11/14	rogid:IYW59Vh17AEnXa6/wLpkIPNE0Bo9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:FB48B9C241D4D16F|rigid:7k9kmTQrmSBvIMvcleDJFlJsRMU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q14790	uniprotkb:Q8XAL7	intact:EBI-78060|uniprotkb:Q14793|uniprotkb:Q14794|uniprotkb:Q14795|uniprotkb:Q14796|uniprotkb:Q15780|uniprotkb:Q15806|uniprotkb:Q53TT5|uniprotkb:Q8TDI1|uniprotkb:Q8TDI2|uniprotkb:Q8TDI3|uniprotkb:Q8TDI4|uniprotkb:Q8TDI5|uniprotkb:Q96T22|uniprotkb:Q9C0K4|uniprotkb:O14676|uniprotkb:Q14791|uniprotkb:Q14792|uniprotkb:Q9UQ81|ensembl:ENSP00000396869.2|ensembl:ENSP00000397528.2|ensembl:ENSP00000412523.2|ensembl:ENSP00000501268.1|ensembl:ENSP00000512369.1	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:casp8_human(display_long)|uniprotkb:CASP8(gene name)|psi-mi:CASP8(display_short)|uniprotkb:MCH5(gene name synonym)|uniprotkb:ICE-like apoptotic protease 5(gene name synonym)|uniprotkb:MORT1-associated ced-3 homolog(gene name synonym)|uniprotkb:FADD-homologous ICE/ced-3-like protease(gene name synonym)|uniprotkb:FADD-like ICE(gene name synonym)|uniprotkb:Apoptotic cysteine protease(gene name synonym)|uniprotkb:Apoptotic protease Mch-5(gene name synonym)|uniprotkb:CAP4(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2012)	pubmed:23516580|imex:IM-28332	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25827472|imex:IM-28332-9	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR10454(orthology-group)|efo:""Orphanet:210159""|efo:""Orphanet:275517""|dip:DIP-30915N|ensembl:ENST00000264275.9|ensembl:ENSP00000264275.5|ensembl:ENST00000323492.11|ensembl:ENSP00000325722.7|ensembl:ENST00000358485.8|ensembl:ENSP00000351273.4|ensembl:ENST00000392258.7|ensembl:ENSP00000376087.3|ensembl:ENST00000392263.6|ensembl:ENSP00000376091.2|ensembl:ENSP00000397528.2|ensembl:ENSP00000412523.2|ensembl:ENSP00000396869.2|ensembl:ENST00000444430.3|ensembl:ENSP00000394434.3|ensembl:ENST00000447616.6|ensembl:ENSP00000388306.2|ensembl:ENSP00000501268.1|ensembl:ENSP00000512369.1|ensembl:ENST00000696068.1|ensembl:ENSP00000512370.1|ensembl:ENST00000696087.1|ensembl:ENSP00000512382.1|ensembl:ENSG00000064012.24(gene)|ensembl:ENST00000413726.6(transcript)|ensembl:ENST00000432109.6(transcript)|ensembl:ENST00000440732.6(transcript)|ensembl:ENST00000673742.1(transcript)|ensembl:ENST00000696067.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006508""(proteolysis)|go:""GO:0006915""(apoptotic process)|go:""GO:0007507""(heart development)|go:""GO:0008233""(peptidase activity)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0030027""(lamellipodium)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032025""(response to cobalt ion)|go:""GO:0032355""(response to estradiol)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032991""(protein-containing complex)|rcsb pdb:1QDU|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042110""(T cell activation)|go:""GO:0042113""(B cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045088""(regulation of innate immune response)|go:""GO:0045471""(response to ethanol)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0051604""(protein maturation)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0060715""(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097264""(self proteolysis)|go:""GO:0097342""(ripoptosome)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001875(Death effector)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR011029(DEATH-like)|interpro:IPR011600(Peptidase C14, caspase catalytic)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033170|mint:Q14790|rcsb pdb:1F9E|rcsb pdb:1I4E|rcsb pdb:1QTN|rcsb pdb:2C2Z|rcsb pdb:2FUN|rcsb pdb:2K7Z|rcsb pdb:2Y1L|rcsb pdb:3H11|rcsb pdb:3KJN|rcsb pdb:3KJQ|rcsb pdb:4JJ7|rcsb pdb:4PRZ|rcsb pdb:4PS1|rcsb pdb:4ZBW|rcsb pdb:5H31|rcsb pdb:5H33|rcsb pdb:5JQE|rcsb pdb:5L08|rcsb pdb:6AGW|rcsb pdb:6PX9|rcsb pdb:7DEE|rcsb pdb:7LVJ|rcsb pdb:7LVM|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-111465|reactome:R-HSA-140534|reactome:R-HSA-168638|reactome:R-HSA-2562578|reactome:R-HSA-264870|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5660668|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75108|reactome:R-HSA-75153|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9686347|reactome:R-HSA-9693928|reactome:R-HSA-9758274|refseq:NP_001073593.1|refseq:NP_001073594.1|refseq:NP_001219.2|refseq:NP_203519.1|refseq:NP_203520.1|refseq:NP_203522.1|refseq:XP_005246943.1|refseq:XP_005246944.1|refseq:XP_005246945.1|refseq:XP_005246946.1|refseq:XP_005246947.1|refseq:XP_005246948.1|refseq:XP_005246949.1|refseq:XP_006712852.1|refseq:XP_006712853.1|refseq:XP_006712856.1"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	"comment:""\""NleF +18 (random amino acids) was generated by removal of the native stop codon.\"""""	figure legend:fig. 1a, 6b sf2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2020/09/08	2024/11/14	rogid:XKI9lMiIKZTtoY2lN/QIm1yTksY9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:FD9C837D682ACA8F|rigid:LrsofKFTDX/YtoxIUUzdM6beICI	false	protein a tag:n-n	mutation disrupting interaction:189-189|mutation disrupting interaction:186-186|mutation disrupting interaction:187-187|mutation disrupting interaction:188-188|mutation disrupting interaction:189-189|luciferase tag:n-n|mutation disrupting interaction:186-189	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P49662	uniprotkb:Q8XAL7	intact:EBI-1057327|uniprotkb:A2NHL8|uniprotkb:A2NHM0|uniprotkb:A2NHL9|uniprotkb:B3KPZ9|uniprotkb:B4DJH5|uniprotkb:B4E2D2|uniprotkb:O95601|uniprotkb:Q7KYX7|uniprotkb:Q9UG96|ensembl:ENSP00000388566.2	intact:EBI-10039292|uniprotkb:Q7AEM9	"psi-mi:casp4_human(display_long)|uniprotkb:ICH2(gene name synonym)|uniprotkb:CASP4(gene name)|psi-mi:CASP4(display_short)|uniprotkb:Protease TX(gene name synonym)|uniprotkb:""ICE(rel)-II""(gene name synonym)|uniprotkb:ICE and Ced-3 homolog 2(gene name synonym)|uniprotkb:Mih1(gene name synonym)"	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2012)	pubmed:23516580|imex:IM-28332	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25827503|imex:IM-28332-11	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001216.1|refseq:NP_150649.1|ensembl:ENSG00000196954.14(gene)|ensembl:ENST00000444739.7(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006915""(apoptotic process)|go:""GO:0008289""(lipid binding)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0050700""(CARD domain binding)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0051604""(protein maturation)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0072558""(NLRP1 inflammasome complex)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0160074""(non-canonical inflammasome complex)|go:""GO:0160075""(non-canonical inflammasome complex assembly)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:2000494""(positive regulation of interleukin-18-mediated signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR011600(Peptidase C14, caspase catalytic)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|mint:P49662|rcsb pdb:6KMZ|rcsb pdb:6NRY|rcsb pdb:7WR0|rcsb pdb:7WR1|rcsb pdb:7WR4|rcsb pdb:7WR5|rcsb pdb:7WR6|rcsb pdb:8J6K|rcsb pdb:8SPB|reactome:R-HSA-168638|reactome:R-HSA-5620971|refseq:XP_011541321.1|refseq:XP_016873886.1|dip:DIP-44806N|panther:PTHR10454(orthology-group)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	"comment:""\""NleF +18 (random amino acids) was generated by removal of the native stop codon.\"""""	figure legend:fig. 1a, 6a sf2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2020/09/08	2024/11/14	rogid:GAgsHH5G984opk7ar2CzWDsDhWA9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:97EE22815FF3E4B3|rigid:2xaT7O5tFGd2uHMtaOdhUChbD9A	false	protein a tag:n-n	mutation disrupting interaction:189-189|mutation disrupting interaction:186-186|mutation disrupting interaction:187-187|mutation decreasing interaction:188-188|luciferase tag:n-n|mutation disrupting interaction:189-189|mutation disrupting interaction:186-189	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P55211	uniprotkb:Q8XAL7	intact:EBI-516799|uniprotkb:O95348|uniprotkb:Q92852|uniprotkb:Q9BQ62|uniprotkb:Q9UEQ3|uniprotkb:Q9UIJ8|uniprotkb:Q53Y70|uniprotkb:Q5JRU9|uniprotkb:Q5UGI1|uniprotkb:B4E1A3|ensembl:ENSP00000330237.5	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:casp9_human(display_long)|uniprotkb:ICE-like apoptotic protease 6(gene name synonym)|uniprotkb:Apoptotic protease Mch-6(gene name synonym)|uniprotkb:Apoptotic protease-activating factor 3(gene name synonym)|uniprotkb:CASP9(gene name)|psi-mi:CASP9(display_short)|uniprotkb:MCH6(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:0729""(luminescence based mammalian interactome mapping)"	Blasche et al. (2012)	pubmed:23516580|imex:IM-28332	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-26303199|imex:IM-28332-12	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001264983.1|refseq:NP_001220.2|refseq:NP_127463.2|refseq:XP_005246071.1|ensembl:ENSG00000132906.18(gene)|ensembl:ENST00000333868.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001822""(kidney development)|go:""GO:0002931""(response to ischemia)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008233""(peptidase activity)|go:""GO:0008303""(caspase complex)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0016485""(protein processing)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030220""(platelet formation)|go:""GO:0032025""(response to cobalt ion)|go:""GO:0032355""(response to estradiol)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034349""(glial cell apoptotic process)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043293""(apoptosome)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044346""(fibroblast apoptotic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051604""(protein maturation)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0071887""(leukocyte apoptotic process)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR011600(Peptidase C14, caspase catalytic)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR042147|mint:P55211|rcsb pdb:1JXQ|rcsb pdb:1NW9|rcsb pdb:2AR9|rcsb pdb:3D9T|rcsb pdb:3V3K|rcsb pdb:3YGS|rcsb pdb:4RHW|rcsb pdb:5JUY|rcsb pdb:5WVC|rcsb pdb:5WVE|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-168638|reactome:R-HSA-198323|reactome:R-HSA-418889|reactome:R-HSA-5674400|reactome:R-HSA-9627069|panther:PTHR10454(orthology-group)|dip:DIP-27625N"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	"comment:""\""NleF +18 (random amino acids) was generated by removal of the native stop codon.\"""""	figure legend:fig. 1a, 6a sf2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293)|taxid:9606(Homo sapiens HEK293 embryonic kidney cell)	-	2020/09/08	2024/11/14	rogid:IYW59Vh17AEnXa6/wLpkIPNE0Bo9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:68C6BB6987B31822|rigid:7k9kmTQrmSBvIMvcleDJFlJsRMU	false	protein a tag:n-n	mutation decreasing interaction:189-189|mutation decreasing interaction:186-186|mutation disrupting interaction:187-187|mutation with no effect:188-188|luciferase tag:n-n|mutation disrupting interaction:189-189|mutation disrupting interaction:186-189	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"
uniprotkb:P55211	uniprotkb:Q8XAL7	intact:EBI-516799|uniprotkb:O95348|uniprotkb:Q92852|uniprotkb:Q9BQ62|uniprotkb:Q9UEQ3|uniprotkb:Q9UIJ8|uniprotkb:Q53Y70|uniprotkb:Q5JRU9|uniprotkb:Q5UGI1|uniprotkb:B4E1A3|ensembl:ENSP00000330237.5	intact:EBI-10039292|uniprotkb:Q7AEM9	psi-mi:casp9_human(display_long)|uniprotkb:ICE-like apoptotic protease 6(gene name synonym)|uniprotkb:Apoptotic protease Mch-6(gene name synonym)|uniprotkb:Apoptotic protease-activating factor 3(gene name synonym)|uniprotkb:CASP9(gene name)|psi-mi:CASP9(display_short)|uniprotkb:MCH6(gene name synonym)	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	"psi-mi:""MI:2318""(force measurement)"	Blasche et al. (2012)	pubmed:23516580|imex:IM-28332	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25827349|imex:IM-28332-5	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001264983.1|refseq:NP_001220.2|refseq:NP_127463.2|refseq:XP_005246071.1|ensembl:ENSG00000132906.18(gene)|ensembl:ENST00000333868.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001822""(kidney development)|go:""GO:0002931""(response to ischemia)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008233""(peptidase activity)|go:""GO:0008303""(caspase complex)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0016485""(protein processing)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030220""(platelet formation)|go:""GO:0032025""(response to cobalt ion)|go:""GO:0032355""(response to estradiol)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034349""(glial cell apoptotic process)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043293""(apoptosome)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044346""(fibroblast apoptotic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051604""(protein maturation)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0071887""(leukocyte apoptotic process)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR011600(Peptidase C14, caspase catalytic)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR042147|mint:P55211|rcsb pdb:1JXQ|rcsb pdb:1NW9|rcsb pdb:2AR9|rcsb pdb:3D9T|rcsb pdb:3V3K|rcsb pdb:3YGS|rcsb pdb:4RHW|rcsb pdb:5JUY|rcsb pdb:5WVC|rcsb pdb:5WVE|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-168638|reactome:R-HSA-198323|reactome:R-HSA-418889|reactome:R-HSA-5674400|reactome:R-HSA-9627069|panther:PTHR10454(orthology-group)|dip:DIP-27625N"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	-	-	-	"figure legend:fig. 1c|comment:""\""The affinity constant (Kd) of NleF binding to immobilized caspase-9 as measured by surface acoustic wave (SAW) technology is ∼39 nM.\""""|comment:""\""Binding kinetic and affinity was analysed on sam®5 BLUE and sam®5 GREEN instruments (SAW Instruments GmbH, Bonn, Germany). Both instruments use the \\""surface acoustic wave\\""-principle for label-free analysis of molecular binding in a flow-through system as described in Perpeet et al. (2006)\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:39.0x10^-9(molar)	2020/09/08	2024/11/14	rogid:IYW59Vh17AEnXa6/wLpkIPNE0Bo9606	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	intact-crc:82C8EB4DF7A8EF20|rigid:7k9kmTQrmSBvIMvcleDJFlJsRMU	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8XAL7	uniprotkb:P55211	intact:EBI-10039292|uniprotkb:Q7AEM9	intact:EBI-516799|uniprotkb:O95348|uniprotkb:Q92852|uniprotkb:Q9BQ62|uniprotkb:Q9UEQ3|uniprotkb:Q9UIJ8|uniprotkb:Q53Y70|uniprotkb:Q5JRU9|uniprotkb:Q5UGI1|uniprotkb:B4E1A3|ensembl:ENSP00000330237.5	psi-mi:nlef_eco57(display_long)|uniprotkb:nleF(gene name)|psi-mi:nleF(display_short)|uniprotkb:Non-LEE-encoded type III effector F(gene name synonym)|uniprotkb:Z6020.1(locus name)|uniprotkb:ECs1815(locus name)	psi-mi:casp9_human(display_long)|uniprotkb:ICE-like apoptotic protease 6(gene name synonym)|uniprotkb:Apoptotic protease Mch-6(gene name synonym)|uniprotkb:Apoptotic protease-activating factor 3(gene name synonym)|uniprotkb:CASP9(gene name)|psi-mi:CASP9(display_short)|uniprotkb:MCH6(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Blasche et al. (2012)	pubmed:23516580|imex:IM-28332	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25827386|imex:IM-28332-7	intact-miscore:0.72	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000938103.1|interpro:IPR031829|interpro:IPR038334|go:""GO:0005576""(extracellular region)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0030430""(host cell cytoplasm)|rcsb pdb:3V3K|mint:Q8XAL7|refseq:NP_309842.1"	"refseq:NP_001264983.1|refseq:NP_001220.2|refseq:NP_127463.2|refseq:XP_005246071.1|ensembl:ENSG00000132906.18(gene)|ensembl:ENST00000333868.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001822""(kidney development)|go:""GO:0002931""(response to ischemia)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008233""(peptidase activity)|go:""GO:0008303""(caspase complex)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0016485""(protein processing)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030220""(platelet formation)|go:""GO:0032025""(response to cobalt ion)|go:""GO:0032355""(response to estradiol)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034349""(glial cell apoptotic process)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043293""(apoptosome)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044346""(fibroblast apoptotic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051604""(protein maturation)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0071887""(leukocyte apoptotic process)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR011600(Peptidase C14, caspase catalytic)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR042147|mint:P55211|rcsb pdb:1JXQ|rcsb pdb:1NW9|rcsb pdb:2AR9|rcsb pdb:3D9T|rcsb pdb:3V3K|rcsb pdb:3YGS|rcsb pdb:4RHW|rcsb pdb:5JUY|rcsb pdb:5WVC|rcsb pdb:5WVE|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-168638|reactome:R-HSA-198323|reactome:R-HSA-418889|reactome:R-HSA-5674400|reactome:R-HSA-9627069|panther:PTHR10454(orthology-group)|dip:DIP-27625N"	pdbe:3V3K	-	-	figure legend:st2 fig.4|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/08	2024/11/14	rogid:HkXeuy5go7xh1ktNxTnkZDm0YLw83334	rogid:IYW59Vh17AEnXa6/wLpkIPNE0Bo9606	intact-crc:7FA3AF142F0B0797|rigid:7k9kmTQrmSBvIMvcleDJFlJsRMU	false	sufficient binding region:25-189	sufficient binding region:141-416	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P0ABE7	uniprotkb:P63096	intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3	intact:EBI-618639|uniprotkb:Q5U074|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|ensembl:ENSP00000343027.3|ensembl:ENSP00000391439.2|ensembl:ENSP00000496800.1|ensembl:ENSP00000496829.1|ensembl:ENSP00000497051.1|ensembl:ENSP00000497179.1|ensembl:ENSP00000497260.1|ensembl:ENSP00000497315.1|ensembl:ENSP00000497379.1|ensembl:ENSP00000497717.1|ensembl:ENSP00000497754.1|ensembl:ENSP00000497760.1|ensembl:ENSP00000497765.1|ensembl:ENSP00000497773.1|ensembl:ENSP00000498091.1|uniprotkb:B4E2V1|uniprotkb:C9J3A4	psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short)	psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	"psi-mi:""MI:0410""(3D electron microscopy)"	Kang et al. (2018)	pubmed:29899450|imex:IM-28379	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-25681738|wwpdb:6CMO|emdb:EMD-7517|imex:IM-28379-1	intact-miscore:0.49	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:8K2W|rcsb pdb:8HNK|rcsb pdb:8HNL|rcsb pdb:8HNM|rcsb pdb:8HNN|rcsb pdb:8JLJ|rcsb pdb:8JLK|rcsb pdb:8JLN|rcsb pdb:8JLO|rcsb pdb:8JLP|rcsb pdb:8JLQ|rcsb pdb:8JLR|rcsb pdb:8JSO|rcsb pdb:7XWO|rcsb pdb:8C9W|rcsb pdb:8CIC|rcsb pdb:8HJ5|rcsb pdb:8IRS|rcsb pdb:8IRT|rcsb pdb:8IRV|rcsb pdb:8K2X|rcsb pdb:8PWN|rcsb pdb:8W8B|rcsb pdb:8A2O|rcsb pdb:8A2P|rcsb pdb:8HQE|rcsb pdb:8HQM|rcsb pdb:8HQN|rcsb pdb:8HVI|rcsb pdb:8IHB|rcsb pdb:8IHF|rcsb pdb:8IHH|rcsb pdb:8IHI|rcsb pdb:8IHJ|rcsb pdb:8IHK|rcsb pdb:8J7E|rcsb pdb:8JJ8|rcsb pdb:8JJL|rcsb pdb:8JMT|rcsb pdb:8TB7|rcsb pdb:8DRE|rcsb pdb:7SQ0|rcsb pdb:7T2G|rcsb pdb:7XKI|rcsb pdb:7XKT|rcsb pdb:8DR8|rcsb pdb:8DRA|rcsb pdb:8DRK|rcsb pdb:8DRN|rcsb pdb:8DRO|rcsb pdb:8DRQ|rcsb pdb:8DS3|rcsb pdb:8DS9|rcsb pdb:8DSA|rcsb pdb:8F74|rcsb pdb:8F77|rcsb pdb:8F79|rcsb pdb:8F7B|rcsb pdb:8F7D|rcsb pdb:8F7E|rcsb pdb:8F7J|rcsb pdb:8FYN|rcsb pdb:8GNE|rcsb pdb:8GY7|rcsb pdb:8HII|rcsb pdb:8HIJ|rcsb pdb:8HIK|rcsb pdb:8HS2|rcsb pdb:8HS3|rcsb pdb:8HSC|rcsb pdb:7F61|rcsb pdb:7PP1|rcsb pdb:7TX7|rcsb pdb:7W53|rcsb pdb:7W55|rcsb pdb:7W56|rcsb pdb:7W57|rcsb pdb:7X5H|rcsb pdb:8DEP|rcsb pdb:8DRD|rcsb pdb:8DRF|rcsb pdb:8DRJ|rcsb pdb:8DRL|rcsb pdb:8DRM|rcsb pdb:7TX6|rcsb pdb:7MK4|rcsb pdb:7N4F|rcsb pdb:7N4G|rcsb pdb:7XTC|rcsb pdb:7XZ5|rcsb pdb:7XZ6|rcsb pdb:7Y12|rcsb pdb:7Y13|rcsb pdb:7Y14|rcsb pdb:7Y15|rcsb pdb:7YXA|rcsb pdb:7ZI0|rcsb pdb:8CU6|rcsb pdb:8CU7|rcsb pdb:8DEN|rcsb pdb:8DJK|rcsb pdb:8DJM|rcsb pdb:8DU3|rcsb pdb:4IAQ|rcsb pdb:7RWW|rcsb pdb:7RWX|rcsb pdb:7RWY|rcsb pdb:7SBF|rcsb pdb:7SU2|rcsb pdb:7T32|rcsb pdb:7TEP|rcsb pdb:7W0L|rcsb pdb:7W0M|rcsb pdb:7W0N|rcsb pdb:7W0O|rcsb pdb:7W0P|rcsb pdb:7WC6|rcsb pdb:7WC7|rcsb pdb:7WC8|rcsb pdb:7WC9|rcsb pdb:7WJ5|rcsb pdb:7XAY|rcsb pdb:7XT8|rcsb pdb:7XT9|rcsb pdb:7XTA|rcsb pdb:7RWV|rcsb pdb:7XTB|rcsb pdb:3U8P|rcsb pdb:7RWU|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:8I7V|rcsb pdb:8I7W|rcsb pdb:8JPN|rcsb pdb:8JPP|rcsb pdb:8K9K|rcsb pdb:8RLN|rcsb pdb:8TH3|rcsb pdb:8TH4|rcsb pdb:8YRG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:5YO3|rcsb pdb:7EZC|rcsb pdb:7F4D|rcsb pdb:7F4F|rcsb pdb:7F4H|rcsb pdb:7F4I|rcsb pdb:7JNI|rcsb pdb:7LR5|rcsb pdb:7LRA|rcsb pdb:7LRB|rcsb pdb:7LRR|rcsb pdb:7LRV|rcsb pdb:7LSJ|rcsb pdb:7LSL|rcsb pdb:7LSN|rcsb pdb:7LV1|rcsb pdb:7LV4|rcsb pdb:7PX4|rcsb pdb:7PYR|rcsb pdb:7WVV|rcsb pdb:7WVW|rcsb pdb:7WVX|rcsb pdb:7WVY|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4EA3|rcsb pdb:7F83|rcsb pdb:7F9Y|rcsb pdb:7F9Z|rcsb pdb:7S8M|rcsb pdb:7S8O|rcsb pdb:7S8P|rcsb pdb:7VOD|rcsb pdb:7VOE|rcsb pdb:4JKV|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6GT3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|rcsb pdb:4YAY|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:7JVR|rcsb pdb:8JT6|rcsb pdb:8FDO|rcsb pdb:8H2G|rcsb pdb:8JT8|rcsb pdb:8RQQ|rcsb pdb:8WRZ|rcsb pdb:8X2K|rcsb pdb:8XV2|rcsb pdb:8XV5|rcsb pdb:8XV9|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|go:""GO:0005506""(iron ion binding)|go:""GO:0009055""(electron transfer activity)|go:""GO:0020037""(heme binding)|go:""GO:0022900""(electron transport chain)|go:""GO:0042597""(periplasmic space)|rcsb pdb:8FY8|rcsb pdb:8FYE|rcsb pdb:8FYL|rcsb pdb:8FYT|rcsb pdb:8FYX|rcsb pdb:8K9L|rcsb pdb:8TS1|rcsb pdb:8TS2|rcsb pdb:8TS3|rcsb pdb:8XVJ|rcsb pdb:8XVK|rcsb pdb:8XVL|rcsb pdb:8YZK|rcsb pdb:8ZFJ|rcsb pdb:8ZFK|rcsb pdb:8ZFL|rcsb pdb:8ZFM|rcsb pdb:8ZMF|rcsb pdb:8ZMG|rcsb pdb:8ZSJ|rcsb pdb:8ZSP|rcsb pdb:8ZSS|rcsb pdb:8ZSV|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:7EXD|rcsb pdb:7MYZ|rcsb pdb:7RM5|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:7XRZ|rcsb pdb:7XY6|rcsb pdb:7XY7|rcsb pdb:7YIT|rcsb pdb:7ZL9|rcsb pdb:7ZLY|rcsb pdb:8F7C|rcsb pdb:8IBU|rcsb pdb:8IBV|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WHA|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV|rcsb pdb:8HN8|rcsb pdb:8HOC|rcsb pdb:8IKJ|rcsb pdb:8J9O|rcsb pdb:8JH7|rcsb pdb:8JHC|rcsb pdb:8K8J|rcsb pdb:8UHB|rcsb pdb:8UT1|rcsb pdb:8UTB|rcsb pdb:8UZJ|rcsb pdb:8V80|rcsb pdb:8V82|rcsb pdb:8V86|rcsb pdb:8V88|rcsb pdb:8V89|rcsb pdb:8V8A|rcsb pdb:8V8C|rcsb pdb:8V8D|rcsb pdb:8W8Q|rcsb pdb:8X5X"	"refseq:NP_002060.4|ensembl:ENSG00000127955.17(gene)|ensembl:ENST00000351004.8(transcript)|ensembl:ENST00000442586.2(transcript)|ensembl:ENST00000648098.1(transcript)|ensembl:ENST00000648306.1(transcript)|ensembl:ENST00000648412.1(transcript)|ensembl:ENST00000648476.1(transcript)|ensembl:ENST00000648663.1(transcript)|ensembl:ENST00000648832.1(transcript)|ensembl:ENST00000648877.1(transcript)|ensembl:ENST00000648953.1(transcript)|ensembl:ENST00000649225.1(transcript)|ensembl:ENST00000649267.1(transcript)|ensembl:ENST00000649487.1(transcript)|ensembl:ENST00000649796.2(transcript)|ensembl:ENST00000649855.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001664""(G protein-coupled receptor binding)|rcsb pdb:2OM2|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005834""(heterotrimeric G-protein complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007188""(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0007198""(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:""GO:0010854""(adenylate cyclase regulator activity)|go:""GO:0019003""(GDP binding)|go:""GO:0030496""(midbody)|go:""GO:0031683""(G-protein beta/gamma-subunit complex binding)|go:""GO:0031749""(D2 dopamine receptor binding)|go:""GO:0031821""(G protein-coupled serotonin receptor binding)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0051301""(cell division)|go:""GO:0060236""(regulation of mitotic spindle organization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072678""(T cell migration)|go:""GO:1904322""(cellular response to forskolin)|go:""GO:1904778""(positive regulation of protein localization to cell cortex)|interpro:IPR001019(""Guanine nucleotide binding protein (G-protein), alpha subunit"")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7DB6|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7DW9|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7EJX|rcsb pdb:7EO2|rcsb pdb:7EO4|rcsb pdb:7EUO|rcsb pdb:7EVY|rcsb pdb:7EVZ|rcsb pdb:7EW0|rcsb pdb:7EW1|rcsb pdb:7EW2|rcsb pdb:7EW3|rcsb pdb:7EW4|rcsb pdb:7EW7|rcsb pdb:7EXD|rcsb pdb:7EZH|rcsb pdb:7EZK|rcsb pdb:7EZM|rcsb pdb:7F1Q|rcsb pdb:7F1R|rcsb pdb:7F1S|rcsb pdb:7F4D|rcsb pdb:7F4F|rcsb pdb:7F4H|rcsb pdb:7F4I|rcsb pdb:7JHJ|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7MTS|rcsb pdb:7NA7|rcsb pdb:7NA8|rcsb pdb:7O7F|rcsb pdb:7P02|rcsb pdb:7RKM|rcsb pdb:7RKN|rcsb pdb:7RKX|rcsb pdb:7RKY|rcsb pdb:7S8M|rcsb pdb:7S8O|rcsb pdb:7SBF|rcsb pdb:7SCG|rcsb pdb:7SQO|rcsb pdb:7T2G|rcsb pdb:7T2H|rcsb pdb:7T6B|rcsb pdb:7T6S|rcsb pdb:7T6T|rcsb pdb:7T6U|rcsb pdb:7T6V|rcsb pdb:7TRK|rcsb pdb:7TRP|rcsb pdb:7TRQ|rcsb pdb:7TRS|rcsb pdb:7TUZ|rcsb pdb:7U2K|rcsb pdb:7U2L|rcsb pdb:7V68|rcsb pdb:7V69|rcsb pdb:7V6A|rcsb pdb:7V9L|rcsb pdb:7VAB|rcsb pdb:7VDH|rcsb pdb:7VDL|rcsb pdb:7VDM|rcsb pdb:7VFX|rcsb pdb:7VGX|rcsb pdb:7VGY|rcsb pdb:7VGZ|rcsb pdb:7VH0|rcsb pdb:7VIE|rcsb pdb:7VIF|rcsb pdb:7VIG|rcsb pdb:7VIH|rcsb pdb:7VKT|rcsb pdb:7VL8|rcsb pdb:7VL9|rcsb pdb:7VLA|rcsb pdb:7VUG|rcsb pdb:7VUY|rcsb pdb:7VUZ|rcsb pdb:7VV3|rcsb pdb:7VV5|rcsb pdb:7W0L|rcsb pdb:7W0M|rcsb pdb:7W0N|rcsb pdb:7W0O|rcsb pdb:7W0P|rcsb pdb:7WF7|rcsb pdb:7WIC|rcsb pdb:7WIG|rcsb pdb:7WJ5|rcsb pdb:7WQ3|rcsb pdb:7WU4|rcsb pdb:7WU5|rcsb pdb:7WU9|rcsb pdb:7WUI|rcsb pdb:7WUJ|rcsb pdb:7WVU|rcsb pdb:7WYB|rcsb pdb:7WZ4|rcsb pdb:7X2V|rcsb pdb:7X5H|rcsb pdb:7X9A|rcsb pdb:7X9B|rcsb pdb:7X9C|rcsb pdb:7X9Y|rcsb pdb:7XA3|rcsb pdb:7XAT|rcsb pdb:7XAU|rcsb pdb:7XAV|rcsb pdb:7XBW|rcsb pdb:7XBX|rcsb pdb:7XK2|rcsb pdb:7XK8|rcsb pdb:7XMR|rcsb pdb:7XMS|rcsb pdb:7XMT|rcsb pdb:7XTA|rcsb pdb:7XXH|rcsb pdb:7Y12|rcsb pdb:7Y15|rcsb pdb:7Y1F|rcsb pdb:7Y64|rcsb pdb:7Y65|rcsb pdb:7Y66|rcsb pdb:7Y67|rcsb pdb:7Y89|rcsb pdb:7YAC|rcsb pdb:7YAE|rcsb pdb:7YDJ|rcsb pdb:7YDP|rcsb pdb:7YKD|rcsb pdb:7YON|rcsb pdb:7YOO|rcsb pdb:7YU3|rcsb pdb:7YU5|rcsb pdb:7YU6|rcsb pdb:7YU7|rcsb pdb:7YU8|rcsb pdb:8DZP|rcsb pdb:8EF5|rcsb pdb:8EF6|rcsb pdb:8EFB|rcsb pdb:8EFL|rcsb pdb:8EFO|rcsb pdb:8EFQ|rcsb pdb:8F7Q|rcsb pdb:8F7R|rcsb pdb:8F7S|rcsb pdb:8F7W|rcsb pdb:8F7X|rcsb pdb:8FEG|rcsb pdb:8FY8|rcsb pdb:8FYE|rcsb pdb:8FYL|rcsb pdb:8FYT|rcsb pdb:8FYX|rcsb pdb:8G05|rcsb pdb:8G59|rcsb pdb:8G94|rcsb pdb:8GAG|rcsb pdb:8GCM|rcsb pdb:8GCP|rcsb pdb:8GDC|rcsb pdb:8GHV|rcsb pdb:8GUQ|rcsb pdb:8GUR|rcsb pdb:8GUS|rcsb pdb:8GUT|rcsb pdb:8H2G|rcsb pdb:8H4I|rcsb pdb:8HBD|rcsb pdb:8HK2|rcsb pdb:8HK3|rcsb pdb:8HK5|rcsb pdb:8HN8|rcsb pdb:8HNK|rcsb pdb:8HNL|rcsb pdb:8HNM|rcsb pdb:8HOC|rcsb pdb:8HQE|rcsb pdb:8HQM|rcsb pdb:8HQN|rcsb pdb:8HS3|rcsb pdb:8HSC|rcsb pdb:8HVI|rcsb pdb:8I7V|rcsb pdb:8I7W|rcsb pdb:8IA8|rcsb pdb:8IC0|rcsb pdb:8ID3|rcsb pdb:8ID4|rcsb pdb:8ID6|rcsb pdb:8ID8|rcsb pdb:8ID9|rcsb pdb:8IHB|rcsb pdb:8IHF|rcsb pdb:8IHH|rcsb pdb:8IHI|rcsb pdb:8IHJ|rcsb pdb:8IJ3|rcsb pdb:8IJA|rcsb pdb:8IJB|rcsb pdb:8IJD|rcsb pdb:8IKG|rcsb pdb:8IKH|rcsb pdb:8INR|rcsb pdb:8IOC|rcsb pdb:8IOD|rcsb pdb:8IRS|rcsb pdb:8IRT|rcsb pdb:8IRV|rcsb pdb:8IU2|rcsb pdb:8IW4|rcsb pdb:8IW7|rcsb pdb:8IW9|rcsb pdb:8IY5|rcsb pdb:8IZ4|rcsb pdb:8J18|rcsb pdb:8J19|rcsb pdb:8J1A|rcsb pdb:8J20|rcsb pdb:8J21|rcsb pdb:8J22|rcsb pdb:8J23|rcsb pdb:8J24|rcsb pdb:8J6I|rcsb pdb:8J6J|rcsb pdb:8J6L|rcsb pdb:8J6P|rcsb pdb:8J6Q|rcsb pdb:8J6R|rcsb pdb:8JD3|rcsb pdb:8JD5|rcsb pdb:8JGB|rcsb pdb:8JGG|rcsb pdb:8JHY|rcsb pdb:8JII|rcsb pdb:8JIL|rcsb pdb:8JIM|rcsb pdb:8JIP|rcsb pdb:8JIR|rcsb pdb:8JIS|rcsb pdb:8JJP|rcsb pdb:8JLJ|rcsb pdb:8JLK|rcsb pdb:8JLR|rcsb pdb:8JPN|rcsb pdb:8JR9|rcsb pdb:8JSO|rcsb pdb:8JSP|rcsb pdb:8JT6|rcsb pdb:8JXT|rcsb pdb:8JXV|rcsb pdb:8JXW|rcsb pdb:8JXX|rcsb pdb:8JZ7|rcsb pdb:8K2X|rcsb pdb:8K3Z|rcsb pdb:8K4N|rcsb pdb:8K4P|rcsb pdb:8KFX|rcsb pdb:8KFY|rcsb pdb:8KFZ|rcsb pdb:8PJK|rcsb pdb:8PKM|rcsb pdb:8SAI|rcsb pdb:8SG1|rcsb pdb:8U1U|rcsb pdb:8U4N|rcsb pdb:8U4O|rcsb pdb:8U4P|rcsb pdb:8U4Q|rcsb pdb:8UGY|rcsb pdb:8UH3|rcsb pdb:8VY7|rcsb pdb:8W8B|rcsb pdb:8W8R|rcsb pdb:8WC3|rcsb pdb:8WC4|rcsb pdb:8WC5|rcsb pdb:8WC6|rcsb pdb:8WC7|rcsb pdb:8WC8|rcsb pdb:8WCA|rcsb pdb:8WG8|rcsb pdb:8WOG|rcsb pdb:8WP1|rcsb pdb:8WRB|rcsb pdb:8WSS|rcsb pdb:8WW2|rcsb pdb:8XBE|rcsb pdb:8XBH|rcsb pdb:8XGM|rcsb pdb:8XOS|rcsb pdb:8XQN|rcsb pdb:8XQO|rcsb pdb:8XQS|rcsb pdb:8XQT|rcsb pdb:8XWP|rcsb pdb:8XWQ|rcsb pdb:8XZF|rcsb pdb:8XZG|rcsb pdb:8XZH|rcsb pdb:8XZI|rcsb pdb:8XZJ|rcsb pdb:8YKV|rcsb pdb:8YKW|rcsb pdb:8YKX|rcsb pdb:8YN5|rcsb pdb:8YN6|rcsb pdb:8YN9|rcsb pdb:8YNA|rcsb pdb:8YUU|rcsb pdb:8YUV|rcsb pdb:8ZBE|rcsb pdb:8ZCJ|rcsb pdb:8ZJD|rcsb pdb:8ZJE|rcsb pdb:8ZQE|rcsb pdb:9AVG|rcsb pdb:9AYF|rcsb pdb:9BQJ|rcsb pdb:9EPP|rcsb pdb:9EPQ|rcsb pdb:9ERX|rcsb pdb:9IJ9|rcsb pdb:9IQT|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9634597|reactome:R-HSA-9660821|refseq:NP_001243343.1|panther:PTHR10218(orthology-group)"	-	-	-	figure legend:Fig 2, Extended Data Fig 2, Extended Data Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/06/17	2024/11/14	rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562	rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606	intact-crc:6AA84C2B8C5EB848|rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E	false	-	his tag:n-n|maltose binding protein tag:n-n	1	1	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"
uniprotkb:P0ABE7	uniprotkb:P63096	intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3	intact:EBI-618639|uniprotkb:Q5U074|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|ensembl:ENSP00000343027.3|ensembl:ENSP00000391439.2|ensembl:ENSP00000496800.1|ensembl:ENSP00000496829.1|ensembl:ENSP00000497051.1|ensembl:ENSP00000497179.1|ensembl:ENSP00000497260.1|ensembl:ENSP00000497315.1|ensembl:ENSP00000497379.1|ensembl:ENSP00000497717.1|ensembl:ENSP00000497754.1|ensembl:ENSP00000497760.1|ensembl:ENSP00000497765.1|ensembl:ENSP00000497773.1|ensembl:ENSP00000498091.1|uniprotkb:B4E2V1|uniprotkb:C9J3A4	psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short)	psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	"psi-mi:""MI:0071""(molecular sieving)"	Kang et al. (2018)	pubmed:29899450|imex:IM-28379	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-25681765|imex:IM-28379-3	intact-miscore:0.49	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:8K2W|rcsb pdb:8HNK|rcsb pdb:8HNL|rcsb pdb:8HNM|rcsb pdb:8HNN|rcsb pdb:8JLJ|rcsb pdb:8JLK|rcsb pdb:8JLN|rcsb pdb:8JLO|rcsb pdb:8JLP|rcsb pdb:8JLQ|rcsb pdb:8JLR|rcsb pdb:8JSO|rcsb pdb:7XWO|rcsb pdb:8C9W|rcsb pdb:8CIC|rcsb pdb:8HJ5|rcsb pdb:8IRS|rcsb pdb:8IRT|rcsb pdb:8IRV|rcsb pdb:8K2X|rcsb pdb:8PWN|rcsb pdb:8W8B|rcsb pdb:8A2O|rcsb pdb:8A2P|rcsb pdb:8HQE|rcsb pdb:8HQM|rcsb pdb:8HQN|rcsb pdb:8HVI|rcsb pdb:8IHB|rcsb pdb:8IHF|rcsb pdb:8IHH|rcsb pdb:8IHI|rcsb pdb:8IHJ|rcsb pdb:8IHK|rcsb pdb:8J7E|rcsb pdb:8JJ8|rcsb pdb:8JJL|rcsb pdb:8JMT|rcsb pdb:8TB7|rcsb pdb:8DRE|rcsb pdb:7SQ0|rcsb pdb:7T2G|rcsb pdb:7XKI|rcsb pdb:7XKT|rcsb pdb:8DR8|rcsb pdb:8DRA|rcsb pdb:8DRK|rcsb pdb:8DRN|rcsb pdb:8DRO|rcsb pdb:8DRQ|rcsb pdb:8DS3|rcsb pdb:8DS9|rcsb pdb:8DSA|rcsb pdb:8F74|rcsb pdb:8F77|rcsb pdb:8F79|rcsb pdb:8F7B|rcsb pdb:8F7D|rcsb pdb:8F7E|rcsb pdb:8F7J|rcsb pdb:8FYN|rcsb pdb:8GNE|rcsb pdb:8GY7|rcsb pdb:8HII|rcsb pdb:8HIJ|rcsb pdb:8HIK|rcsb pdb:8HS2|rcsb pdb:8HS3|rcsb pdb:8HSC|rcsb pdb:7F61|rcsb pdb:7PP1|rcsb pdb:7TX7|rcsb pdb:7W53|rcsb pdb:7W55|rcsb pdb:7W56|rcsb pdb:7W57|rcsb pdb:7X5H|rcsb pdb:8DEP|rcsb pdb:8DRD|rcsb pdb:8DRF|rcsb pdb:8DRJ|rcsb pdb:8DRL|rcsb pdb:8DRM|rcsb pdb:7TX6|rcsb pdb:7MK4|rcsb pdb:7N4F|rcsb pdb:7N4G|rcsb pdb:7XTC|rcsb pdb:7XZ5|rcsb pdb:7XZ6|rcsb pdb:7Y12|rcsb pdb:7Y13|rcsb pdb:7Y14|rcsb pdb:7Y15|rcsb pdb:7YXA|rcsb pdb:7ZI0|rcsb pdb:8CU6|rcsb pdb:8CU7|rcsb pdb:8DEN|rcsb pdb:8DJK|rcsb pdb:8DJM|rcsb pdb:8DU3|rcsb pdb:4IAQ|rcsb pdb:7RWW|rcsb pdb:7RWX|rcsb pdb:7RWY|rcsb pdb:7SBF|rcsb pdb:7SU2|rcsb pdb:7T32|rcsb pdb:7TEP|rcsb pdb:7W0L|rcsb pdb:7W0M|rcsb pdb:7W0N|rcsb pdb:7W0O|rcsb pdb:7W0P|rcsb pdb:7WC6|rcsb pdb:7WC7|rcsb pdb:7WC8|rcsb pdb:7WC9|rcsb pdb:7WJ5|rcsb pdb:7XAY|rcsb pdb:7XT8|rcsb pdb:7XT9|rcsb pdb:7XTA|rcsb pdb:7RWV|rcsb pdb:7XTB|rcsb pdb:3U8P|rcsb pdb:7RWU|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:8I7V|rcsb pdb:8I7W|rcsb pdb:8JPN|rcsb pdb:8JPP|rcsb pdb:8K9K|rcsb pdb:8RLN|rcsb pdb:8TH3|rcsb pdb:8TH4|rcsb pdb:8YRG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:5YO3|rcsb pdb:7EZC|rcsb pdb:7F4D|rcsb pdb:7F4F|rcsb pdb:7F4H|rcsb pdb:7F4I|rcsb pdb:7JNI|rcsb pdb:7LR5|rcsb pdb:7LRA|rcsb pdb:7LRB|rcsb pdb:7LRR|rcsb pdb:7LRV|rcsb pdb:7LSJ|rcsb pdb:7LSL|rcsb pdb:7LSN|rcsb pdb:7LV1|rcsb pdb:7LV4|rcsb pdb:7PX4|rcsb pdb:7PYR|rcsb pdb:7WVV|rcsb pdb:7WVW|rcsb pdb:7WVX|rcsb pdb:7WVY|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4EA3|rcsb pdb:7F83|rcsb pdb:7F9Y|rcsb pdb:7F9Z|rcsb pdb:7S8M|rcsb pdb:7S8O|rcsb pdb:7S8P|rcsb pdb:7VOD|rcsb pdb:7VOE|rcsb pdb:4JKV|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6GT3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|rcsb pdb:4YAY|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:7JVR|rcsb pdb:8JT6|rcsb pdb:8FDO|rcsb pdb:8H2G|rcsb pdb:8JT8|rcsb pdb:8RQQ|rcsb pdb:8WRZ|rcsb pdb:8X2K|rcsb pdb:8XV2|rcsb pdb:8XV5|rcsb pdb:8XV9|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|go:""GO:0005506""(iron ion binding)|go:""GO:0009055""(electron transfer activity)|go:""GO:0020037""(heme binding)|go:""GO:0022900""(electron transport chain)|go:""GO:0042597""(periplasmic space)|rcsb pdb:8FY8|rcsb pdb:8FYE|rcsb pdb:8FYL|rcsb pdb:8FYT|rcsb pdb:8FYX|rcsb pdb:8K9L|rcsb pdb:8TS1|rcsb pdb:8TS2|rcsb pdb:8TS3|rcsb pdb:8XVJ|rcsb pdb:8XVK|rcsb pdb:8XVL|rcsb pdb:8YZK|rcsb pdb:8ZFJ|rcsb pdb:8ZFK|rcsb pdb:8ZFL|rcsb pdb:8ZFM|rcsb pdb:8ZMF|rcsb pdb:8ZMG|rcsb pdb:8ZSJ|rcsb pdb:8ZSP|rcsb pdb:8ZSS|rcsb pdb:8ZSV|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:7EXD|rcsb pdb:7MYZ|rcsb pdb:7RM5|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:7XRZ|rcsb pdb:7XY6|rcsb pdb:7XY7|rcsb pdb:7YIT|rcsb pdb:7ZL9|rcsb pdb:7ZLY|rcsb pdb:8F7C|rcsb pdb:8IBU|rcsb pdb:8IBV|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WHA|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV|rcsb pdb:8HN8|rcsb pdb:8HOC|rcsb pdb:8IKJ|rcsb pdb:8J9O|rcsb pdb:8JH7|rcsb pdb:8JHC|rcsb pdb:8K8J|rcsb pdb:8UHB|rcsb pdb:8UT1|rcsb pdb:8UTB|rcsb pdb:8UZJ|rcsb pdb:8V80|rcsb pdb:8V82|rcsb pdb:8V86|rcsb pdb:8V88|rcsb pdb:8V89|rcsb pdb:8V8A|rcsb pdb:8V8C|rcsb pdb:8V8D|rcsb pdb:8W8Q|rcsb pdb:8X5X"	"refseq:NP_002060.4|ensembl:ENSG00000127955.17(gene)|ensembl:ENST00000351004.8(transcript)|ensembl:ENST00000442586.2(transcript)|ensembl:ENST00000648098.1(transcript)|ensembl:ENST00000648306.1(transcript)|ensembl:ENST00000648412.1(transcript)|ensembl:ENST00000648476.1(transcript)|ensembl:ENST00000648663.1(transcript)|ensembl:ENST00000648832.1(transcript)|ensembl:ENST00000648877.1(transcript)|ensembl:ENST00000648953.1(transcript)|ensembl:ENST00000649225.1(transcript)|ensembl:ENST00000649267.1(transcript)|ensembl:ENST00000649487.1(transcript)|ensembl:ENST00000649796.2(transcript)|ensembl:ENST00000649855.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001664""(G protein-coupled receptor binding)|rcsb pdb:2OM2|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005834""(heterotrimeric G-protein complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007188""(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0007198""(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:""GO:0010854""(adenylate cyclase regulator activity)|go:""GO:0019003""(GDP binding)|go:""GO:0030496""(midbody)|go:""GO:0031683""(G-protein beta/gamma-subunit complex binding)|go:""GO:0031749""(D2 dopamine receptor binding)|go:""GO:0031821""(G protein-coupled serotonin receptor binding)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0051301""(cell division)|go:""GO:0060236""(regulation of mitotic spindle organization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072678""(T cell migration)|go:""GO:1904322""(cellular response to forskolin)|go:""GO:1904778""(positive regulation of protein localization to cell cortex)|interpro:IPR001019(""Guanine nucleotide binding protein (G-protein), alpha subunit"")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7DB6|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7DW9|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7EJX|rcsb pdb:7EO2|rcsb pdb:7EO4|rcsb pdb:7EUO|rcsb pdb:7EVY|rcsb pdb:7EVZ|rcsb pdb:7EW0|rcsb pdb:7EW1|rcsb pdb:7EW2|rcsb pdb:7EW3|rcsb pdb:7EW4|rcsb pdb:7EW7|rcsb pdb:7EXD|rcsb pdb:7EZH|rcsb pdb:7EZK|rcsb pdb:7EZM|rcsb pdb:7F1Q|rcsb pdb:7F1R|rcsb pdb:7F1S|rcsb pdb:7F4D|rcsb pdb:7F4F|rcsb pdb:7F4H|rcsb pdb:7F4I|rcsb pdb:7JHJ|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7MTS|rcsb pdb:7NA7|rcsb pdb:7NA8|rcsb pdb:7O7F|rcsb pdb:7P02|rcsb pdb:7RKM|rcsb pdb:7RKN|rcsb pdb:7RKX|rcsb pdb:7RKY|rcsb pdb:7S8M|rcsb pdb:7S8O|rcsb pdb:7SBF|rcsb pdb:7SCG|rcsb pdb:7SQO|rcsb pdb:7T2G|rcsb pdb:7T2H|rcsb pdb:7T6B|rcsb pdb:7T6S|rcsb pdb:7T6T|rcsb pdb:7T6U|rcsb pdb:7T6V|rcsb pdb:7TRK|rcsb pdb:7TRP|rcsb pdb:7TRQ|rcsb pdb:7TRS|rcsb pdb:7TUZ|rcsb pdb:7U2K|rcsb pdb:7U2L|rcsb pdb:7V68|rcsb pdb:7V69|rcsb pdb:7V6A|rcsb pdb:7V9L|rcsb pdb:7VAB|rcsb pdb:7VDH|rcsb pdb:7VDL|rcsb pdb:7VDM|rcsb pdb:7VFX|rcsb pdb:7VGX|rcsb pdb:7VGY|rcsb pdb:7VGZ|rcsb pdb:7VH0|rcsb pdb:7VIE|rcsb pdb:7VIF|rcsb pdb:7VIG|rcsb pdb:7VIH|rcsb pdb:7VKT|rcsb pdb:7VL8|rcsb pdb:7VL9|rcsb pdb:7VLA|rcsb pdb:7VUG|rcsb pdb:7VUY|rcsb pdb:7VUZ|rcsb pdb:7VV3|rcsb pdb:7VV5|rcsb pdb:7W0L|rcsb pdb:7W0M|rcsb pdb:7W0N|rcsb pdb:7W0O|rcsb pdb:7W0P|rcsb pdb:7WF7|rcsb pdb:7WIC|rcsb pdb:7WIG|rcsb pdb:7WJ5|rcsb pdb:7WQ3|rcsb pdb:7WU4|rcsb pdb:7WU5|rcsb pdb:7WU9|rcsb pdb:7WUI|rcsb pdb:7WUJ|rcsb pdb:7WVU|rcsb pdb:7WYB|rcsb pdb:7WZ4|rcsb pdb:7X2V|rcsb pdb:7X5H|rcsb pdb:7X9A|rcsb pdb:7X9B|rcsb pdb:7X9C|rcsb pdb:7X9Y|rcsb pdb:7XA3|rcsb pdb:7XAT|rcsb pdb:7XAU|rcsb pdb:7XAV|rcsb pdb:7XBW|rcsb pdb:7XBX|rcsb pdb:7XK2|rcsb pdb:7XK8|rcsb pdb:7XMR|rcsb pdb:7XMS|rcsb pdb:7XMT|rcsb pdb:7XTA|rcsb pdb:7XXH|rcsb pdb:7Y12|rcsb pdb:7Y15|rcsb pdb:7Y1F|rcsb pdb:7Y64|rcsb pdb:7Y65|rcsb pdb:7Y66|rcsb pdb:7Y67|rcsb pdb:7Y89|rcsb pdb:7YAC|rcsb pdb:7YAE|rcsb pdb:7YDJ|rcsb pdb:7YDP|rcsb pdb:7YKD|rcsb pdb:7YON|rcsb pdb:7YOO|rcsb pdb:7YU3|rcsb pdb:7YU5|rcsb pdb:7YU6|rcsb pdb:7YU7|rcsb pdb:7YU8|rcsb pdb:8DZP|rcsb pdb:8EF5|rcsb pdb:8EF6|rcsb pdb:8EFB|rcsb pdb:8EFL|rcsb pdb:8EFO|rcsb pdb:8EFQ|rcsb pdb:8F7Q|rcsb pdb:8F7R|rcsb pdb:8F7S|rcsb pdb:8F7W|rcsb pdb:8F7X|rcsb pdb:8FEG|rcsb pdb:8FY8|rcsb pdb:8FYE|rcsb pdb:8FYL|rcsb pdb:8FYT|rcsb pdb:8FYX|rcsb pdb:8G05|rcsb pdb:8G59|rcsb pdb:8G94|rcsb pdb:8GAG|rcsb pdb:8GCM|rcsb pdb:8GCP|rcsb pdb:8GDC|rcsb pdb:8GHV|rcsb pdb:8GUQ|rcsb pdb:8GUR|rcsb pdb:8GUS|rcsb pdb:8GUT|rcsb pdb:8H2G|rcsb pdb:8H4I|rcsb pdb:8HBD|rcsb pdb:8HK2|rcsb pdb:8HK3|rcsb pdb:8HK5|rcsb pdb:8HN8|rcsb pdb:8HNK|rcsb pdb:8HNL|rcsb pdb:8HNM|rcsb pdb:8HOC|rcsb pdb:8HQE|rcsb pdb:8HQM|rcsb pdb:8HQN|rcsb pdb:8HS3|rcsb pdb:8HSC|rcsb pdb:8HVI|rcsb pdb:8I7V|rcsb pdb:8I7W|rcsb pdb:8IA8|rcsb pdb:8IC0|rcsb pdb:8ID3|rcsb pdb:8ID4|rcsb pdb:8ID6|rcsb pdb:8ID8|rcsb pdb:8ID9|rcsb pdb:8IHB|rcsb pdb:8IHF|rcsb pdb:8IHH|rcsb pdb:8IHI|rcsb pdb:8IHJ|rcsb pdb:8IJ3|rcsb pdb:8IJA|rcsb pdb:8IJB|rcsb pdb:8IJD|rcsb pdb:8IKG|rcsb pdb:8IKH|rcsb pdb:8INR|rcsb pdb:8IOC|rcsb pdb:8IOD|rcsb pdb:8IRS|rcsb pdb:8IRT|rcsb pdb:8IRV|rcsb pdb:8IU2|rcsb pdb:8IW4|rcsb pdb:8IW7|rcsb pdb:8IW9|rcsb pdb:8IY5|rcsb pdb:8IZ4|rcsb pdb:8J18|rcsb pdb:8J19|rcsb pdb:8J1A|rcsb pdb:8J20|rcsb pdb:8J21|rcsb pdb:8J22|rcsb pdb:8J23|rcsb pdb:8J24|rcsb pdb:8J6I|rcsb pdb:8J6J|rcsb pdb:8J6L|rcsb pdb:8J6P|rcsb pdb:8J6Q|rcsb pdb:8J6R|rcsb pdb:8JD3|rcsb pdb:8JD5|rcsb pdb:8JGB|rcsb pdb:8JGG|rcsb pdb:8JHY|rcsb pdb:8JII|rcsb pdb:8JIL|rcsb pdb:8JIM|rcsb pdb:8JIP|rcsb pdb:8JIR|rcsb pdb:8JIS|rcsb pdb:8JJP|rcsb pdb:8JLJ|rcsb pdb:8JLK|rcsb pdb:8JLR|rcsb pdb:8JPN|rcsb pdb:8JR9|rcsb pdb:8JSO|rcsb pdb:8JSP|rcsb pdb:8JT6|rcsb pdb:8JXT|rcsb pdb:8JXV|rcsb pdb:8JXW|rcsb pdb:8JXX|rcsb pdb:8JZ7|rcsb pdb:8K2X|rcsb pdb:8K3Z|rcsb pdb:8K4N|rcsb pdb:8K4P|rcsb pdb:8KFX|rcsb pdb:8KFY|rcsb pdb:8KFZ|rcsb pdb:8PJK|rcsb pdb:8PKM|rcsb pdb:8SAI|rcsb pdb:8SG1|rcsb pdb:8U1U|rcsb pdb:8U4N|rcsb pdb:8U4O|rcsb pdb:8U4P|rcsb pdb:8U4Q|rcsb pdb:8UGY|rcsb pdb:8UH3|rcsb pdb:8VY7|rcsb pdb:8W8B|rcsb pdb:8W8R|rcsb pdb:8WC3|rcsb pdb:8WC4|rcsb pdb:8WC5|rcsb pdb:8WC6|rcsb pdb:8WC7|rcsb pdb:8WC8|rcsb pdb:8WCA|rcsb pdb:8WG8|rcsb pdb:8WOG|rcsb pdb:8WP1|rcsb pdb:8WRB|rcsb pdb:8WSS|rcsb pdb:8WW2|rcsb pdb:8XBE|rcsb pdb:8XBH|rcsb pdb:8XGM|rcsb pdb:8XOS|rcsb pdb:8XQN|rcsb pdb:8XQO|rcsb pdb:8XQS|rcsb pdb:8XQT|rcsb pdb:8XWP|rcsb pdb:8XWQ|rcsb pdb:8XZF|rcsb pdb:8XZG|rcsb pdb:8XZH|rcsb pdb:8XZI|rcsb pdb:8XZJ|rcsb pdb:8YKV|rcsb pdb:8YKW|rcsb pdb:8YKX|rcsb pdb:8YN5|rcsb pdb:8YN6|rcsb pdb:8YN9|rcsb pdb:8YNA|rcsb pdb:8YUU|rcsb pdb:8YUV|rcsb pdb:8ZBE|rcsb pdb:8ZCJ|rcsb pdb:8ZJD|rcsb pdb:8ZJE|rcsb pdb:8ZQE|rcsb pdb:9AVG|rcsb pdb:9AYF|rcsb pdb:9BQJ|rcsb pdb:9EPP|rcsb pdb:9EPQ|rcsb pdb:9ERX|rcsb pdb:9IJ9|rcsb pdb:9IQT|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9634597|reactome:R-HSA-9660821|refseq:NP_001243343.1|panther:PTHR10218(orthology-group)"	-	-	-	figure legend:Extended Data Fig 1a, b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/06/17	2024/11/14	rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562	rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606	intact-crc:243E383B8DB3BE4E|rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E	false	-	-	1	1	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"	"psi-mi:""MI:0396""(predetermined participant)|psi-mi:""MI:2287""(identification by structure determination)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q7L591	intact:EBI-25400937	intact:EBI-2834978|uniprotkb:Q8N864|uniprotkb:Q9H666|uniprotkb:Q9BQB3|uniprotkb:E9PAT0|uniprotkb:H7BXS0	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:dok3_human(display_long)|uniprotkb:DOK3(gene name)|psi-mi:DOK3(display_short)|uniprotkb:Downstream of tyrosine kinase 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0101003""(ficolin-1-rich granule membrane)|reactome:R-HSA-6798695|refseq:NP_001295164.1|refseq:NP_001295165.1|refseq:NP_001138347.1|refseq:NP_001138348.1|refseq:NP_079148.2|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|refseq:XP_005266044.1|interpro:IPR037751|mint:Q7L591|interpro:IPR050996|panther:PTHR21258(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:G9EW2VdiFHPeonrp8T8Qbt2qQZQ9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q96AE4	intact:EBI-25400937	intact:EBI-711404|ensembl:ENSP00000359804.2|uniprotkb:Q12828	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:fubp1_human(display_long)|uniprotkb:FUBP1(gene name)|psi-mi:FUBP1(display_short)|uniprotkb:DNA helicase V(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"ensembl:ENSG00000162613.18(gene)|ensembl:ENST00000370768.7(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010628""(positive regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|interpro:IPR048249|interpro:IPR048250|interpro:IPR048251|interpro:IPR048252|mint:Q96AE4|rcsb pdb:1J4W|rcsb pdb:2KXH|rcsb pdb:4LIJ|rcsb pdb:6Y24|rcsb pdb:6Y2C|rcsb pdb:6Y2D|rcsb pdb:8P25|refseq:NP_003893.2|refseq:NP_001290362.1|refseq:XP_016858232.1|dip:DIP-47273N|panther:PTHR10288(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:38IaQgYv8qLMAryXO0lbfzgjjsM9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:P23246	intact:EBI-25400937	intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748.5	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"efo:""Orphanet:319308""|ensembl:ENSG00000116560.12(gene)|ensembl:ENST00000357214.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0042382""(paraspeckles)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042754""(negative regulation of circadian rhythm)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1902177""(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|rcsb pdb:7PU5|rcsb pdb:7SP0|rcsb pdb:7UJ1|rcsb pdb:7UK1|reactome:R-HSA-8849468|reactome:R-HSA-9635465|refseq:NP_005057.1|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N|panther:PTHR23189(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q15233	intact:EBI-25400937	intact:EBI-350527|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3|ensembl:ENSP00000276079.8|ensembl:ENSP00000362947.1|ensembl:ENSP00000406673.2|ensembl:ENSP00000410299.2|ensembl:ENSP00000415777.2|ensembl:ENSP00000503031.1|ensembl:ENSP00000503233.1|ensembl:ENSP00000504314.1|ensembl:ENSP00000504351.1	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"efo:""Orphanet:319308""|efo:""Orphanet:466791""|ensembl:ENSG00000147140.17(gene)|ensembl:ENST00000276079.13(transcript)|ensembl:ENST00000373841.5(transcript)|ensembl:ENST00000420903.6(transcript)|ensembl:ENST00000450092.6(transcript)|ensembl:ENST00000454976.2(transcript)|ensembl:ENST00000677274.1(transcript)|ensembl:ENST00000677446.1(transcript)|ensembl:ENST00000677612.1(transcript)|ensembl:ENST00000678231.1(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0042382""(paraspeckles)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903377""(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|rcsb pdb:7PU5|refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|dip:DIP-29951N|panther:PTHR23189(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q15437	intact:EBI-25400937	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544.2|ensembl:ENSP00000338844.3|ensembl:ENSP00000366685.1|ensembl:ENSP00000497473.1	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"ensembl:ENSG00000101310.17(gene)|ensembl:ENST00000262544.6(transcript)|ensembl:ENST00000336714.8(transcript)|ensembl:ENST00000377465.6(transcript)|ensembl:ENST00000650089.1(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008270""(zinc ion binding)|go:""GO:0012505""(endomembrane system)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|refseq:XP_016883082.1|efo:""Orphanet:201""|efo:""Orphanet:98873""|panther:PTHR11141(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q9H3S7	intact:EBI-25400937	intact:EBI-724478|uniprotkb:Q7KZF8|uniprotkb:Q8N6Z5|uniprotkb:Q9BSR5|uniprotkb:Q9P257|uniprotkb:Q9UG03|uniprotkb:Q9UMZ4|uniprotkb:A8K0D7|ensembl:ENSP00000265562.4	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:ptn23_human(display_long)|uniprotkb:His domain-containing protein tyrosine phosphatase(gene name synonym)|uniprotkb:Protein tyrosine phosphatase TD14(gene name synonym)|uniprotkb:PTPN23(gene name)|psi-mi:PTPN23(display_short)|uniprotkb:KIAA1471(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"efo:""Orphanet:528084""|ensembl:ENSG00000076201.16(gene)|ensembl:ENST00000265562.5(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0010633""(negative regulation of epithelial cell migration)|go:""GO:0016604""(nuclear body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0032456""(endocytic recycling)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0060271""(cilium assembly)|go:""GO:0061357""(positive regulation of Wnt protein secretion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1903387""(positive regulation of homophilic cell adhesion)|go:""GO:1903393""(positive regulation of adherens junction organization)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004328(BRO1)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR025304|interpro:IPR029021|interpro:IPR038499|mint:Q9H3S7|rcsb pdb:3RAU|rcsb pdb:5CRU|rcsb pdb:5CRV|rcsb pdb:5LM1|rcsb pdb:5LM2|rcsb pdb:5MJY|rcsb pdb:5MJZ|rcsb pdb:5MK0|rcsb pdb:5MK1|rcsb pdb:5MK2|rcsb pdb:5MK3|reactome:R-HSA-9008059|refseq:NP_001291411.1|refseq:NP_056281.1|dip:DIP-29923N|panther:PTHR23030(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:PeqzQLL4J4v9IMuHFBlb+1B4Ujw9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:O94855	intact:EBI-25400937	intact:EBI-748817|intact:EBI-1212263|uniprotkb:Q8IYI7|ensembl:ENSP00000280551.6	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:sc24d_human(display_long)|uniprotkb:KIAA0755(gene name synonym)|uniprotkb:SEC24D(gene name)|psi-mi:SEC24D(display_short)|uniprotkb:SEC24-related protein D(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"ensembl:ENSG00000150961.15(gene)|ensembl:ENST00000280551.11(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008270""(zinc ion binding)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|interpro:IPR050550|mint:O94855|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_001304995.1|refseq:NP_055637.2|refseq:XP_005263436.1|efo:""Orphanet:2050""|efo:""Orphanet:216796""|panther:PTHR13803(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:CuxIZAR5xQP4Kc0ucDYGZ+siB8w9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q15436	intact:EBI-25400937	intact:EBI-81088|uniprotkb:B2R5P4|uniprotkb:Q8NE16|ensembl:ENSP00000306881.6|uniprotkb:B3KXI2	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:sc23a_human(display_long)|uniprotkb:SEC23A(gene name)|psi-mi:SEC23A(display_short)|uniprotkb:SEC23-related protein A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"ensembl:ENSG00000100934.15(gene)|ensembl:ENST00000307712.11(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008270""(zinc ion binding)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15436|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:2YRC|rcsb pdb:2YRD|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|rcsb pdb:5VNE|rcsb pdb:5VNF|rcsb pdb:5VNG|rcsb pdb:5VNH|rcsb pdb:5VNI|rcsb pdb:5VNJ|rcsb pdb:5VNK|rcsb pdb:5VNL|rcsb pdb:5VNM|rcsb pdb:5VNN|rcsb pdb:5VNO|rcsb pdb:8HR0|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_006355.2|panther:PTHR11141(orthology-group)|efo:""Orphanet:50814"""	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:u1FCes02jPb3CGRj1aDkzpbSiuI9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q92945	intact:EBI-25400937	intact:EBI-1049099|uniprotkb:O00301|uniprotkb:Q59EZ9|uniprotkb:Q5U4P6|uniprotkb:Q9UNT5|uniprotkb:Q9UQH5|intact:EBI-5455671|ensembl:ENSP00000381216.2	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:fubp2_human(display_long)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:KHSRP(gene name)|psi-mi:KHSRP(display_short)|uniprotkb:FUBP2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_003676.2|ensembl:ENSG00000088247.19(gene)|ensembl:ENST00000398148.7(transcript)|go:""GO:0000375""(RNA splicing, via transesterification reactions)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0010586""(miRNA metabolic process)|go:""GO:0010989""(negative regulation of low-density lipoprotein particle clearance)|go:""GO:0016020""(membrane)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045019""(negative regulation of nitric oxide biosynthetic process)|go:""GO:0051028""(mRNA transport)|go:""GO:0061014""(positive regulation of mRNA catabolic process)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0071345""(cellular response to cytokine stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|interpro:IPR047369|interpro:IPR047370|interpro:IPR047371|interpro:IPR047372|mint:Q92945|rcsb pdb:2HH2|rcsb pdb:2HH3|rcsb pdb:2JVZ|rcsb pdb:2OPU|rcsb pdb:2OPV|rcsb pdb:4B8T|reactome:R-HSA-380994|reactome:R-HSA-450604|dip:DIP-48484N|panther:PTHR10288(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:hlybJllTqSgPgtwwz3kc12zDYh49606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q15654	intact:EBI-25400937	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|uniprotkb:F2ZC07|uniprotkb:F2ZC08|ensembl:ENSP00000200457.4	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_003293.2|dip:DIP-34466N|ensembl:ENSG00000087077.14(gene)|ensembl:ENST00000200457.9(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003723""(RNA binding)|go:""GO:0005149""(interleukin-1 receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0019900""(kinase binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0043009""(chordate embryonic development)|go:""GO:0046872""(metal ion binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|panther:PTHR24212(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:P50570	intact:EBI-25400937	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890.6	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)|uniprotkb:Dynamin 2(gene name synonym)|uniprotkb:Dynamin II(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"dip:DIP-31244N|panther:PTHR11566(orthology-group)|efo:""Orphanet:100044""|efo:""Orphanet:169189""|efo:""Orphanet:228179""|efo:""Orphanet:363409""|ensembl:ENSG00000079805.19(gene)|ensembl:ENST00000355667.11(transcript)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001891""(phagocytic cup)|go:""GO:0001931""(uropod)|go:""GO:0002102""(podosome)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005925""(focal adhesion)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006909""(phagocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008017""(microtubule binding)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016185""(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019899""(enzyme binding)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030496""(midbody)|go:""GO:0030516""(regulation of axon extension)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0033572""(transferrin transport)|go:""GO:0043005""(neuron projection)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0045202""(synapse)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051258""(protein polymerization)|go:""GO:0055037""(recycling endosome)|go:""GO:0061024""(membrane organization)|go:""GO:0061572""(actin filament bundle organization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097749""(membrane tubulation)|go:""GO:0098793""(presynapse)|go:""GO:0099050""(vesicle scission)|go:""GO:1903526""(negative regulation of membrane tubulation)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR045063|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|refseq:NP_004936.2"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q16630	intact:EBI-25400937	intact:EBI-358410|uniprotkb:Q53ES1|uniprotkb:Q9BSJ7|uniprotkb:Q9BW18|intact:EBI-740029|uniprotkb:A8K7K9|ensembl:ENSP00000391774.2	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:cpsf6_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"panther:PTHR23204(orthology-group)|refseq:NP_008938.2|ensembl:ENSG00000111605.18(gene)|ensembl:ENST00000435070.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005726""(perichromatin fibrils)|go:""GO:0005737""(cytoplasm)|go:""GO:0005847""(mRNA cleavage and polyadenylation specificity factor complex)|go:""GO:0005849""(mRNA cleavage factor complex)|go:""GO:0006397""(mRNA processing)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0035061""(interchromatin granule)|go:""GO:0042382""(paraspeckles)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0046833""(positive regulation of RNA export from nucleus)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051290""(protein heterotetramerization)|go:""GO:0110104""(mRNA alternative polyadenylation)|go:""GO:0180010""(co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway)|go:""GO:1990448""(exon-exon junction complex binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979|mint:Q16630|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:4B4N|rcsb pdb:4U0A|rcsb pdb:4U0B|rcsb pdb:4WYM|rcsb pdb:6AY9|rcsb pdb:6GX9|rcsb pdb:7SNQ|rcsb pdb:7ZUD|rcsb pdb:8CL1|rcsb pdb:8EJL|rcsb pdb:8GDV|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001287876.1|dip:DIP-34501N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:nvZBuI+X/m+5MGIsfh2ToVe5nFs9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:P50552	intact:EBI-25400937	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|ensembl:ENSP00000245932.5|intact:EBI-28992147	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_003361.1|ensembl:ENSG00000125753.15(gene)|ensembl:ENST00000245932.11(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007411""(axon guidance)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031527""(filopodium membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|mint:P50552|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR038023|rcsb pdb:1EGX|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:8GAT|rcsb pdb:8GAU|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N|panther:PTHR11202(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:P22234	intact:EBI-25400937	intact:EBI-712261|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|ensembl:ENSP00000264221.2|ensembl:ENSP00000421096.1|intact:EBI-21352784	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"ensembl:ENSG00000128050.9(gene)|ensembl:ENST00000264221.6(transcript)|ensembl:ENST00000512576.3(transcript)|go:""GO:0004638""(phosphoribosylaminoimidazole carboxylase activity)|go:""GO:0004639""(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006177""(GMP biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0044208""('de novo' AMP biosynthetic process)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097294""('de novo' XMP biosynthetic process)|interpro:IPR000031(""1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase"")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|interpro:IPR050089|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|rcsb pdb:6YB9|rcsb pdb:7ALE|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1|panther:PTHR43599(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:O94979	intact:EBI-25400937	intact:EBI-1767898|uniprotkb:Q17RR5|uniprotkb:Q5H9P6|uniprotkb:Q5XG74|uniprotkb:Q659G7|uniprotkb:Q6ZU90|uniprotkb:Q7LCX9|uniprotkb:Q86TJ0|uniprotkb:Q8IZH4|uniprotkb:Q9P048|uniprotkb:Q9P0A6|uniprotkb:Q9UM05|uniprotkb:Q9UM06|uniprotkb:B7ZKZ7|intact:EBI-25605813|uniprotkb:B7ZL00|uniprotkb:B4DIW6|uniprotkb:H7C2W3|ensembl:ENSP00000347329.2|ensembl:ENSP00000378721.2|ensembl:ENSP00000400926.1	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:sc31a_human(display_long)|uniprotkb:SEC31A(gene name)|psi-mi:SEC31A(display_short)|uniprotkb:KIAA0905(gene name synonym)|uniprotkb:SEC31L1(gene name synonym)|uniprotkb:HSPC275(orf name)|uniprotkb:HSPC334(orf name)|uniprotkb:SEC31-related protein A(gene name synonym)|uniprotkb:SEC31-like protein 1(gene name synonym)|uniprotkb:ABP125(gene name synonym)|uniprotkb:ABP130(gene name synonym)|uniprotkb:Web1-like protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_001070674.1|refseq:NP_001070675.1|refseq:NP_001070676.1|refseq:NP_057295.2|refseq:NP_001177978.1|refseq:NP_001287673.1|refseq:NP_001287674.1|refseq:NP_001305048.1|refseq:NP_001305049.1|dip:DIP-40438N|ensembl:ENSG00000138674.17(gene)|ensembl:ENST00000355196.6(transcript)|ensembl:ENST00000395310.7(transcript)|ensembl:ENST00000448323.5(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0015031""(protein transport)|go:""GO:0030120""(vesicle coat)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024298|interpro:IPR036322|interpro:IPR040251|mint:O94979|rcsb pdb:3WXA|rcsb pdb:7SUL|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-381038|reactome:R-HSA-9725370|reactome:R-HSA-983170|panther:PTHR13923(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:MvtQi/4RmQ0siNtNoYH6k1rPv1Y9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:O43809	intact:EBI-25400937	intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291.5|intact:EBI-21354068	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_008937.1|ensembl:ENSG00000167005.14(gene)|ensembl:ENST00000300291.10(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005847""(mRNA cleavage and polyadenylation specificity factor complex)|go:""GO:0005849""(mRNA cleavage factor complex)|go:""GO:0006397""(mRNA processing)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016604""(nuclear body)|go:""GO:0030154""(cell differentiation)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0042382""(paraspeckles)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051290""(protein heterotetramerization)|go:""GO:0110104""(mRNA alternative polyadenylation)|go:""GO:0180010""(co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway)|go:""GO:2000738""(positive regulation of stem cell differentiation)|go:""GO:2000975""(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N|panther:PTHR13047(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q9NTZ6	intact:EBI-25400937	intact:EBI-310707|uniprotkb:E1P5R6|uniprotkb:B3KRU2|uniprotkb:O94865|uniprotkb:Q8N3B1|uniprotkb:Q9H196|ensembl:ENSP00000352668.1|ensembl:ENSP00000363217.3|ensembl:ENSP00000363228.3	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:rbm12_human(display_long)|uniprotkb:HRIHFB2091(orf name)|uniprotkb:RBM12(gene name)|psi-mi:RBM12(display_short)|uniprotkb:KIAA0765(gene name synonym)|uniprotkb:RNA-binding motif protein 12(gene name synonym)|uniprotkb:SH3/WW domain anchor protein in the nucleus(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_001185767.1|refseq:NP_001185769.1|refseq:NP_006038.2|refseq:NP_690051.1|ensembl:ENSG00000244462.8(gene)|ensembl:ENST00000359646.1(transcript)|ensembl:ENST00000374104.7(transcript)|ensembl:ENST00000374114.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034591|interpro:IPR034594|interpro:IPR034854|interpro:IPR034855|interpro:IPR034856|interpro:IPR035979|interpro:IPR050666|mint:Q9NTZ6|rcsb pdb:1WEL|rcsb pdb:2CPY|rcsb pdb:2DNN|rcsb pdb:2EK1|rcsb pdb:2EK6|panther:PTHR13976(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:Hcz7OUumWYuRnRNMjwFYUZBquVo9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:P55735	intact:EBI-25400937	intact:EBI-1046596|ensembl:ENSP00000312122.4|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:SEC13A(gene name synonym)|uniprotkb:GATOR2 complex protein SEC13(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_001129704.1|refseq:NP_899195.1|ensembl:ENSG00000157020.18(gene)|ensembl:ENST00000350697.8(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0031080""(nuclear pore outer ring)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0032527""(protein exit from endoplasmic reticulum)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0051028""(mRNA transport)|go:""GO:0061700""(GATOR2 complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:0090114""(COPII-coated vesicle budding)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904263""(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:5A9Q|rcsb pdb:7PEQ|rcsb pdb:7R5J|rcsb pdb:7R5K|rcsb pdb:7UHY|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|refseq:XP_016862508.1|dip:DIP-39091N|panther:PTHR11024(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q8WUM4	intact:EBI-25400937	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|ensembl:ENSP00000307387.3|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|intact:EBI-28983290|uniprotkb:C5MQH7|intact:EBI-10971645	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_037506.2|ensembl:ENSG00000170248.15(gene)|ensembl:ENST00000307296.8(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0000915""(actomyosin contractile ring assembly)|go:""GO:0001772""(immunological synapse)|go:""GO:0005768""(endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006915""(apoptotic process)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0031871""(proteinase activated receptor binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0042470""(melanosome)|go:""GO:0042641""(actomyosin)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045199""(maintenance of epithelial cell apical/basal polarity)|go:""GO:0046755""(viral budding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0061952""(midbody abscission)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090543""(Flemming body)|go:""GO:0090559""(regulation of membrane permeability)|go:""GO:0090611""(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0097734""(extracellular exosome biogenesis)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903551""(regulation of extracellular exosome assembly)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001155901.1|refseq:NP_001243121.1|dip:DIP-29327N|panther:PTHR23030(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q96I24	intact:EBI-25400937	intact:EBI-954200|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8|ensembl:ENSP00000318177.9|intact:EBI-21357206	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_003925.1|dip:DIP-50124N|ensembl:ENSG00000107164.17(gene)|ensembl:ENST00000319725.10(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005840""(ribosome)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043198""(dendritic shaft)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|panther:PTHR10288(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q6P2E9	intact:EBI-25400937	intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811.5	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_055144.3|dip:DIP-31192N|ensembl:ENSG00000038358.15(gene)|ensembl:ENST00000358933.10(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0031087""(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|interpro:IPR036322|interpro:IPR044938|interpro:IPR045152|interpro:IPR049404|mint:Q6P2E9|reactome:R-HSA-430039|panther:PTHR15598(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q96M27	intact:EBI-25400937	intact:EBI-2560879|intact:EBI-28987821|uniprotkb:Q8NEZ7|uniprotkb:Q86Y42|uniprotkb:Q69YM8|uniprotkb:Q7L2U7|uniprotkb:Q96AJ3|uniprotkb:Q8IVL4|uniprotkb:Q8IVJ4|ensembl:ENSP00000296666.9|ensembl:ENSP00000520434.1	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:prrc1_human(display_long)|uniprotkb:PRRC1(gene name)|psi-mi:PRRC1(display_short)|uniprotkb:Proline-rich and coiled-coil-containing protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_570721.1|refseq:NP_001273737.1|refseq:XP_006714592.1|ensembl:ENSG00000164244.22(gene)|ensembl:ENST00000296666.13(transcript)|ensembl:ENST00000715263.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|go:""GO:0042802""(identical protein binding)|interpro:IPR026533|interpro:IPR026534|interpro:IPR029001|mint:Q96M27|panther:PTHR23276(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:PLR9r6Zo0BDrdOArwQjuDiVPIik9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAS2	uniprotkb:Q9UI08	intact:EBI-25400937	intact:EBI-346653|uniprotkb:O95884|uniprotkb:Q7Z522|uniprotkb:Q8TBV1|uniprotkb:Q9UF25|uniprotkb:A8K105|uniprotkb:Q9UIC2|uniprotkb:B7Z3I5|ensembl:ENSP00000384720.2	psi-mi:a0a0h3las2_mycte(display_long)|uniprotkb:apa(gene name)|psi-mi:apa(display_short)|uniprotkb:Fibronectin attachment protein(gene name synonym)|uniprotkb:ERDMAN_2049(locus name)	psi-mi:evl_human(display_long)|uniprotkb:EVL(gene name)|psi-mi:EVL(display_short)|uniprotkb:RNB6(gene name synonym)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25400946|imex:IM-27663-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0050840""(extracellular matrix binding)|refseq:WP_003409337.1|interpro:IPR010801(Fibronectin-attachment)|mint:A0A0H3LAS2"	"refseq:NP_057421.1|refseq:NP_001317150.1|panther:PTHR11202(orthology-group)|ensembl:ENSG00000196405.13(gene)|ensembl:ENST00000402714.6(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007015""(actin filament organization)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007411""(axon guidance)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010633""(negative regulation of epithelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:1900028""(negative regulation of ruffle assembly)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR038023|mint:Q9UI08|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-5663220"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:Gl2ed3g9zS0EakZeOzHCMVJOMVg652616	rogid:ZYA6pfvqC68sm/0egUg4hBif/Pc9606	intact-crc:E535EF713EE48BC5|rigid:otmzVH8cynxtVfj86IsNptBRfqk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LD76	uniprotkb:O00410	intact:EBI-25401032	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219.3|ensembl:ENSP00000418393.1|ensembl:ENSP00000499125.1|intact:EBI-21353074	psi-mi:a0a0h3ld76_mycte(display_long)|uniprotkb:cfp6(gene name)|psi-mi:cfp6(display_short)|uniprotkb:ERDMAN_3293(locus name)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401039|imex:IM-27663-3	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR019692|mint:A0A0H3LD76"	"refseq:NP_002262.3|refseq:XP_005254109.1|refseq:XP_005254110.1|ensembl:ENSG00000065150.21(gene)|ensembl:ENST00000357602.7(transcript)|ensembl:ENST00000490680.5(transcript)|ensembl:ENST00000651721.2(transcript)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003723""(RNA binding)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0006610""(ribosomal protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0045736""(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0071230""(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|refseq:XP_016876051.1|dip:DIP-41042N|panther:PTHR10527(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:7Yvjh7xFoRoT5VcnhV8vhD8Nafs652616	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	intact-crc:B81AA8812D59ED70|rigid:esTgPtdlp8N9oj7huV82p+427v8	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LD76	uniprotkb:P13284	intact:EBI-25401032	intact:EBI-2868897|uniprotkb:Q9UL08|uniprotkb:Q76MF9|uniprotkb:Q8NEI4|uniprotkb:Q8WU77|ensembl:ENSP00000384886.1	psi-mi:a0a0h3ld76_mycte(display_long)|uniprotkb:cfp6(gene name)|psi-mi:cfp6(display_short)|uniprotkb:ERDMAN_3293(locus name)	psi-mi:gilt_human(display_long)|uniprotkb:IFI30(gene name)|psi-mi:IFI30(display_short)|uniprotkb:GILT(gene name synonym)|uniprotkb:Gamma-interferon-inducible protein IP-30(gene name synonym)|uniprotkb:IP30(gene name synonym)|uniprotkb:Legumaturain(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401039|imex:IM-27663-3	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR019692|mint:A0A0H3LD76"	"refseq:NP_006323.2|ensembl:ENSG00000216490.4(gene)|ensembl:ENST00000407280.4(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005764""(lysosome)|go:""GO:0005829""(cytosol)|go:""GO:0016667""(oxidoreductase activity, acting on a sulfur group of donors)|go:""GO:0016671""(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0030054""(cell junction)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|interpro:IPR004911(Gamma interferon inducible lysosomal thiol reductase GILT)|mint:P13284|reactome:R-HSA-2132295|reactome:R-HSA-877300|panther:PTHR13234(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:7Yvjh7xFoRoT5VcnhV8vhD8Nafs652616	rogid:Ek7pdIMSbIkfoPrLZZDYR72JjFo9606	intact-crc:B81AA8812D59ED70|rigid:esTgPtdlp8N9oj7huV82p+427v8	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LD76	uniprotkb:P26373	intact:EBI-25401032	intact:EBI-356849|uniprotkb:Q3KQT8|uniprotkb:Q9BPX0|uniprotkb:Q567Q8|uniprotkb:B4DLX3|uniprotkb:F5H1S2|ensembl:ENSP00000307889.5|ensembl:ENSP00000376811.3|ensembl:ENSP00000455009.1	psi-mi:a0a0h3ld76_mycte(display_long)|uniprotkb:cfp6(gene name)|psi-mi:cfp6(display_short)|uniprotkb:ERDMAN_3293(locus name)	psi-mi:rl13_human(display_long)|uniprotkb:RPL13(gene name)|psi-mi:RPL13(display_short)|uniprotkb:BBC1(gene name synonym)|uniprotkb:Breast basic conserved protein 1(gene name synonym)|uniprotkb:OK/SW-cl.46(orf name)|uniprotkb:60S ribosomal protein L13(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401039|imex:IM-27663-3	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR019692|mint:A0A0H3LD76"	"rcsb pdb:6OM0|ensembl:ENSG00000167526.15(gene)|ensembl:ENST00000311528.10(transcript)|ensembl:ENST00000393099.4(transcript)|ensembl:ENST00000567815.5(transcript)|go:""GO:0001824""(blastocyst development)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0016020""(membrane)|go:""GO:0022625""(cytosolic large ribosomal subunit)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0045202""(synapse)|go:""GO:0060348""(bone development)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P26373|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:7F5S|rcsb pdb:7OW7|rcsb pdb:7QVP|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8A3D|rcsb pdb:8FKP|rcsb pdb:8FKQ|rcsb pdb:8FKR|rcsb pdb:8FKS|rcsb pdb:8FKT|rcsb pdb:8FKU|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|rcsb pdb:8FKZ|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FL9|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLC|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8FLF|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8GLP|rcsb pdb:8IDT|rcsb pdb:8IDY|rcsb pdb:8IE3|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8INK|rcsb pdb:8IPD|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR1|rcsb pdb:8IR3|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8OJ8|rcsb pdb:8QFD|rcsb pdb:8QOI|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9G8M|rcsb pdb:9GMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000968.2|refseq:NP_001230059.1|refseq:NP_001230060.1|refseq:NP_150254.1|efo:""Orphanet:370015""|panther:PTHR11722(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:7Yvjh7xFoRoT5VcnhV8vhD8Nafs652616	rogid:2SZ+AEe41Ystwj9t9I0Z1cZ5GQ49606	intact-crc:B81AA8812D59ED70|rigid:esTgPtdlp8N9oj7huV82p+427v8	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LEU4	uniprotkb:Q147U7	intact:EBI-25401047	intact:EBI-11735944|uniprotkb:B3KW20|ensembl:ENSP00000380671.2	psi-mi:a0a0h3leu4_mycte(display_long)|uniprotkb:cpsA(gene name)|psi-mi:cpsA(display_short)|uniprotkb:ERDMAN_3823(locus name)	psi-mi:smco1_human(display_long)|uniprotkb:SMCO1(gene name)|psi-mi:SMCO1(display_short)|uniprotkb:C3orf43(gene name synonym)|uniprotkb:Single-pass membrane protein with coiled-coil domains 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401056|imex:IM-27663-21	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR050922|refseq:WP_003900866.1|interpro:IPR027381|interpro:IPR004474(Cell envelope-related transcriptional attenuator)|mint:A0A0H3LEU4"	"refseq:NP_001071125.1|refseq:NP_001307402.1|ensembl:ENSG00000214097.5(gene)|ensembl:ENST00000397537.3(transcript)|go:""GO:0016020""(membrane)|interpro:IPR027875|mint:Q147U7|panther:PTHR35979(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:UJUdWGLXH7xY+KhahvpdPofwY6U652616	rogid:FUEt2WUxWGiszbF99ntaUMlYWHU9606	intact-crc:AE2A5359E73C617E|rigid:gEzgtZOwNv+BCVcjtEKJJ53HxsU	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LG06	uniprotkb:O43663	intact:EBI-25401064	intact:EBI-741137|uniprotkb:Q9BSB6|uniprotkb:A6NC44|uniprotkb:B4DLR1|uniprotkb:H9KV59|ensembl:ENSP00000377793.3|intact:EBI-11127601	psi-mi:a0a0h3lg06_mycte(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:ERDMAN_4249(locus name)	psi-mi:prc1_human(display_long)|uniprotkb:PRC1(gene name)|psi-mi:PRC1(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401076|imex:IM-27663-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0044315""(protein secretion by the type VII secretion system)|go:""GO:0052027""(symbiont-mediated perturbation of host signal transduction pathway)|go:""GO:0052170""(symbiont-mediated suppression of host innate immune response)|refseq:WP_003399963.1|interpro:IPR036689|interpro:IPR010310(Protein of unknown function DUF909)|mint:A0A0H3LG06"	"refseq:NP_003972.1|refseq:NP_001254509.1|ensembl:ENSG00000198901.14(gene)|ensembl:ENST00000394249.8(transcript)|go:""GO:0000022""(mitotic spindle elongation)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000922""(spindle pole)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005876""(spindle microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0008017""(microtubule binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0019894""(kinesin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030496""(midbody)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0045171""(intercellular bridge)|go:""GO:0051256""(mitotic spindle midzone assembly)|go:""GO:0051301""(cell division)|go:""GO:0070938""(contractile ring)|go:""GO:1990023""(mitotic spindle midzone)|interpro:IPR007145(MAP65/ASE1)|mint:O43663|rcsb pdb:3NRX|rcsb pdb:3NRY|rcsb pdb:4L3I|rcsb pdb:4L6Y|rcsb pdb:5KMG|rcsb pdb:7VBG|reactome:R-HSA-5625900|dip:DIP-34436N|panther:PTHR19321(orthology-group)"	-	-	crc64:28393C5B1B3662F3	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q652616	rogid:AV2d6TYVsFn2J598pi/GmPdgK7A9606	intact-crc:D656F506DE9E0BEF|rigid:Ud9WUaD+YOeh5oza6GmJ0GoksCc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LG06	uniprotkb:O00264	intact:EBI-25401064	intact:EBI-1045534|uniprotkb:Q9UGJ9|uniprotkb:B7Z1L3|ensembl:ENSP00000217971.7	psi-mi:a0a0h3lg06_mycte(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:ERDMAN_4249(locus name)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401076|imex:IM-27663-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0044315""(protein secretion by the type VII secretion system)|go:""GO:0052027""(symbiont-mediated perturbation of host signal transduction pathway)|go:""GO:0052170""(symbiont-mediated suppression of host innate immune response)|refseq:WP_003399963.1|interpro:IPR036689|interpro:IPR010310(Protein of unknown function DUF909)|mint:A0A0H3LG06"	"efo:""Orphanet:98994""|ensembl:ENSG00000101856.10(gene)|ensembl:ENST00000217971.8(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0005496""(steroid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0030868""(smooth endoplasmic reticulum membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044297""(cell body)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:0140077""(positive regulation of lipoprotein transport)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|interpro:IPR050577|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|refseq:NP_001269550.1|refseq:NP_006658.1|panther:PTHR10281(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q652616	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	intact-crc:D656F506DE9E0BEF|rigid:Ud9WUaD+YOeh5oza6GmJ0GoksCc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LG06	uniprotkb:P50336	intact:EBI-25401064	intact:EBI-716607|uniprotkb:Q5VTW8|uniprotkb:D3DVG0|ensembl:ENSP00000343943.5|ensembl:ENSP00000356978.4	psi-mi:a0a0h3lg06_mycte(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:ERDMAN_4249(locus name)	psi-mi:ppox_human(display_long)|uniprotkb:PPOX(gene name)|psi-mi:PPOX(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401076|imex:IM-27663-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0044315""(protein secretion by the type VII secretion system)|go:""GO:0052027""(symbiont-mediated perturbation of host signal transduction pathway)|go:""GO:0052170""(symbiont-mediated suppression of host innate immune response)|refseq:WP_003399963.1|interpro:IPR036689|interpro:IPR010310(Protein of unknown function DUF909)|mint:A0A0H3LG06"	"ensembl:ENSG00000143224.18(gene)|ensembl:ENST00000352210.9(transcript)|ensembl:ENST00000367999.9(transcript)|go:""GO:0004729""(oxygen-dependent protoporphyrinogen oxidase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006779""(porphyrin-containing compound biosynthetic process)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0006784""(heme A biosynthetic process)|go:""GO:0006785""(heme B biosynthetic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0048034""(heme O biosynthetic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070819""(menaquinone-dependent protoporphyrinogen oxidase activity)|interpro:IPR002937(Amine oxidase)|interpro:IPR004572(Protoporphyrinogen oxidase)|interpro:IPR036188|interpro:IPR050464|mint:P50336|rcsb pdb:3NKS|rcsb pdb:4IVM|rcsb pdb:4IVO|reactome:R-HSA-189451|refseq:NP_000300.1|refseq:NP_001116236.1|efo:""Orphanet:79473""|panther:PTHR42923(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q652616	rogid:Y+DmgW/MogsQTWJlcL2S08lRNIk9606	intact-crc:D656F506DE9E0BEF|rigid:Ud9WUaD+YOeh5oza6GmJ0GoksCc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LG06	uniprotkb:Q9H0U4	intact:EBI-25401064	intact:EBI-1045214|uniprotkb:A8K7S1|ensembl:ENSP00000310226.6	psi-mi:a0a0h3lg06_mycte(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:ERDMAN_4249(locus name)	psi-mi:rab1b_human(display_long)|uniprotkb:RAB1B(gene name)|psi-mi:RAB1B(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401076|imex:IM-27663-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0044315""(protein secretion by the type VII secretion system)|go:""GO:0052027""(symbiont-mediated perturbation of host signal transduction pathway)|go:""GO:0052170""(symbiont-mediated suppression of host innate immune response)|refseq:WP_003399963.1|interpro:IPR036689|interpro:IPR010310(Protein of unknown function DUF909)|mint:A0A0H3LG06"	"refseq:NP_112243.1|dip:DIP-42462N|ensembl:ENSG00000174903.16(gene)|ensembl:ENST00000311481.11(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0019068""(virion assembly)|go:""GO:0030133""(transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:Q9H0U4|rcsb pdb:3JZA|rcsb pdb:3NKV|rcsb pdb:4HLQ|rcsb pdb:4I1O|rcsb pdb:5O74|rcsb pdb:5SZH|rcsb pdb:5SZK|rcsb pdb:6SKU|rcsb pdb:8ALK|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q652616	rogid:EI6DHq7xCboSkoqGY5NmVY4Iqf09606	intact-crc:D656F506DE9E0BEF|rigid:Ud9WUaD+YOeh5oza6GmJ0GoksCc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LG06	uniprotkb:P62820	intact:EBI-25401064	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:a0a0h3lg06_mycte(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:ERDMAN_4249(locus name)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401076|imex:IM-27663-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0044315""(protein secretion by the type VII secretion system)|go:""GO:0052027""(symbiont-mediated perturbation of host signal transduction pathway)|go:""GO:0052170""(symbiont-mediated suppression of host innate immune response)|refseq:WP_003399963.1|interpro:IPR036689|interpro:IPR010310(Protein of unknown function DUF909)|mint:A0A0H3LG06"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q652616	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:D656F506DE9E0BEF|rigid:Ud9WUaD+YOeh5oza6GmJ0GoksCc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LG06	uniprotkb:Q9H7Z7	intact:EBI-25401064	intact:EBI-681645|uniprotkb:Q53EW9|uniprotkb:Q5SYV6|uniprotkb:Q96GI0|uniprotkb:Q96GL2|ensembl:ENSP00000345341.6	psi-mi:a0a0h3lg06_mycte(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:ERDMAN_4249(locus name)	"psi-mi:pges2_human(display_long)|uniprotkb:Microsomal prostaglandin E synthase 2(gene name synonym)|uniprotkb:PTGES2(gene name)|psi-mi:PTGES2(display_short)|uniprotkb:PGES2(gene name synonym)|uniprotkb:C9orf15(gene name synonym)|uniprotkb:Membrane-associated prostaglandin E synthase-2(gene name synonym)|uniprotkb:""Prostaglandin-H(2) E-isomerase""(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401076|imex:IM-27663-23	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0044315""(protein secretion by the type VII secretion system)|go:""GO:0052027""(symbiont-mediated perturbation of host signal transduction pathway)|go:""GO:0052170""(symbiont-mediated suppression of host innate immune response)|refseq:WP_003399963.1|interpro:IPR036689|interpro:IPR010310(Protein of unknown function DUF909)|mint:A0A0H3LG06"	"refseq:NP_001243264.1|refseq:NP_079348.1|refseq:NP_945176.1|ensembl:ENSG00000148334.16(gene)|ensembl:ENST00000338961.11(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003677""(DNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0016829""(lyase activity)|go:""GO:0019371""(cyclooxygenase pathway)|go:""GO:0020037""(heme binding)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0036134""(12-hydroxyheptadecatrienoic acid synthase activity)|go:""GO:0043295""(glutathione binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046903""(secretion)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050220""(prostaglandin-E synthase activity)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR034334|interpro:IPR034335|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:Q9H7Z7|reactome:R-HSA-2162123|reactome:R-HSA-6798695|panther:PTHR12782(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q652616	rogid:DFALgQTHlFSBHZUZBKTJNxxSqjk9606	intact-crc:D656F506DE9E0BEF|rigid:Ud9WUaD+YOeh5oza6GmJ0GoksCc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LN59	uniprotkb:Q99567	intact:EBI-25401108	intact:EBI-726178|uniprotkb:Q9BWE5|uniprotkb:D3DTM2|intact:EBI-28967918|ensembl:ENSP00000458954.1	psi-mi:a0a0h3ln59_mycte(display_long)|uniprotkb:ERDMAN_4257(locus name)	psi-mi:nup88_human(display_long)|uniprotkb:Nucleoporin Nup88(gene name synonym)|uniprotkb:88 kDa nucleoporin(gene name synonym)|uniprotkb:NUP88(gene name)|psi-mi:NUP88(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401114|imex:IM-27663-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR038332|refseq:WP_003399995.1|interpro:IPR041275|interpro:IPR054056|mint:A0A0H3LN59	"efo:""Orphanet:994""|ensembl:ENSG00000108559.13(gene)|ensembl:ENST00000573584.6(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0017056""(structural constituent of nuclear pore)|interpro:IPR019321|interpro:IPR037700|mint:Q99567|rcsb pdb:7MNI|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9705671|refseq:NP_001307582.1|refseq:NP_002523.2|panther:PTHR13257(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:J1uUpDLGDHIN1D3ylg+KHjHQuYs652616	rogid:4e7YTurNWkXUn9zj0JiD2muc94A9606	intact-crc:FD992DD3A8A9195E|rigid:WUwlcJNBei0bWfqmj/Lx7ZDBm2o	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LN59	uniprotkb:Q96EP5	intact:EBI-25401108	intact:EBI-2133162|uniprotkb:Q96MJ3|uniprotkb:Q9NRR9|ensembl:ENSP00000233078.4	psi-mi:a0a0h3ln59_mycte(display_long)|uniprotkb:ERDMAN_4257(locus name)	psi-mi:dazp1_human(display_long)|uniprotkb:DAZAP1(gene name)|psi-mi:DAZAP1(display_short)|uniprotkb:Deleted in azoospermia-associated protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401114|imex:IM-27663-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR038332|refseq:WP_003399995.1|interpro:IPR041275|interpro:IPR054056|mint:A0A0H3LN59	"ensembl:ENSG00000071626.17(gene)|ensembl:ENST00000233078.9(transcript)|go:""GO:0001673""(male germ cell nucleus)|go:""GO:0001893""(maternal placenta development)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0030154""(cell differentiation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034046""(""poly(G) binding"")|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034131|interpro:IPR034134|interpro:IPR035979|mint:Q96EP5|rcsb pdb:2DGS|rcsb pdb:2DH8|refseq:NP_061832.2|refseq:NP_733829.1|panther:PTHR48027(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:J1uUpDLGDHIN1D3ylg+KHjHQuYs652616	rogid:4uZCZTXZGnZAD9tBcurmc8RhGwY9606	intact-crc:FD992DD3A8A9195E|rigid:WUwlcJNBei0bWfqmj/Lx7ZDBm2o	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LN59	uniprotkb:Q9BYJ9	intact:EBI-25401108	intact:EBI-1051237|uniprotkb:Q8N3G5|uniprotkb:Q8TBT1|uniprotkb:Q96AN4|uniprotkb:Q96S57|uniprotkb:Q9BTI7|uniprotkb:Q9NX79|ensembl:ENSP00000359364.3	psi-mi:a0a0h3ln59_mycte(display_long)|uniprotkb:ERDMAN_4257(locus name)	psi-mi:ythd1_human(display_long)|uniprotkb:Dermatomyositis associated with cancer putative autoantigen 1(gene name synonym)|uniprotkb:YTHDF1(gene name)|psi-mi:YTHDF1(display_short)|uniprotkb:C20orf21(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401114|imex:IM-27663-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR038332|refseq:WP_003399995.1|interpro:IPR041275|interpro:IPR054056|mint:A0A0H3LN59	"refseq:NP_060268.2|ensembl:ENSG00000149658.18(gene)|ensembl:ENST00000370339.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0002376""(immune system process)|go:""GO:0002577""(regulation of antigen processing and presentation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0007612""(learning)|go:""GO:0007613""(memory)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0034063""(stress granule assembly)|go:""GO:0043022""(ribosome binding)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0061157""(mRNA destabilization)|go:""GO:0070925""(organelle assembly)|go:""GO:1900271""(regulation of long-term synaptic potentiation)|go:""GO:1902667""(regulation of axon guidance)|go:""GO:1990247""(N6-methyladenosine-containing RNA reader activity)|interpro:IPR007275(YT521-B-like protein)|interpro:IPR045168|mint:Q9BYJ9|rcsb pdb:4RCI|rcsb pdb:4RCJ|rcsb pdb:7PCU|rcsb pdb:7QKN|rcsb pdb:7QL7|rcsb pdb:7YYE|rcsb pdb:7YYF|rcsb pdb:7YYJ|rcsb pdb:7YZ8|rcsb pdb:8BS4|panther:PTHR12357(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:J1uUpDLGDHIN1D3ylg+KHjHQuYs652616	rogid:uzNKPfwF7I+6hLk6l8iiDOhuBcQ9606	intact-crc:FD992DD3A8A9195E|rigid:WUwlcJNBei0bWfqmj/Lx7ZDBm2o	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LN59	uniprotkb:Q9BUJ2	intact:EBI-25401108	intact:EBI-1018153|intact:EBI-2563529|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863.2	psi-mi:a0a0h3ln59_mycte(display_long)|uniprotkb:ERDMAN_4257(locus name)	psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401114|imex:IM-27663-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR038332|refseq:WP_003399995.1|interpro:IPR041275|interpro:IPR054056|mint:A0A0H3LN59	"refseq:NP_008971.2|refseq:NP_653333.1|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N|ensembl:ENSG00000105323.18(gene)|ensembl:ENST00000392006.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006396""(RNA processing)|go:""GO:0009615""(response to virus)|go:""GO:0019899""(enzyme binding)|go:""GO:0045202""(synapse)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|rcsb pdb:1ZRJ|panther:PTHR12381(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:J1uUpDLGDHIN1D3ylg+KHjHQuYs652616	rogid:IahA7SVR1NmvldrWKQlAwApinQE9606	intact-crc:FD992DD3A8A9195E|rigid:WUwlcJNBei0bWfqmj/Lx7ZDBm2o	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LN59	uniprotkb:P35658	intact:EBI-25401108	intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400.5	psi-mi:a0a0h3ln59_mycte(display_long)|uniprotkb:ERDMAN_4257(locus name)	psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401114|imex:IM-27663-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR038332|refseq:WP_003399995.1|interpro:IPR041275|interpro:IPR054056|mint:A0A0H3LN59	"efo:""Orphanet:402014""|efo:""Orphanet:99861""|ensembl:ENSG00000126883.19(gene)|ensembl:ENST00000359428.10(transcript)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0046822""(regulation of nucleocytoplasmic transport)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:1990876""(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC|rcsb pdb:3FMO|rcsb pdb:3FMP|rcsb pdb:5DIS|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9705671|refseq:NP_001305253.1|refseq:NP_001305254.1|refseq:NP_005076.3|dip:DIP-38367N|panther:PTHR23193(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:J1uUpDLGDHIN1D3ylg+KHjHQuYs652616	rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606	intact-crc:FD992DD3A8A9195E|rigid:WUwlcJNBei0bWfqmj/Lx7ZDBm2o	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LN28	uniprotkb:Q9UKB1	intact:EBI-25401139	intact:EBI-355189|uniprotkb:Q9P2S8|uniprotkb:Q9P2S9|uniprotkb:Q9Y4C6|uniprotkb:B2RC98|ensembl:ENSP00000265094.5	psi-mi:a0a0h3ln28_mycte(display_long)|uniprotkb:ERDMAN_4222(locus name)	psi-mi:fbw1b_human(display_long)|uniprotkb:KIAA0696(gene name synonym)|uniprotkb:FBXW11(gene name)|psi-mi:FBXW11(display_short)|uniprotkb:BTRCP2(gene name synonym)|uniprotkb:FBW1B(gene name synonym)|uniprotkb:FBXW1B(gene name synonym)|uniprotkb:F-box/WD repeat-containing protein 1B(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP2(gene name synonym)|uniprotkb:Homologous to Slimb protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401144|imex:IM-27663-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|mint:A0A0H3LN28"	"ensembl:ENSG00000072803.18(gene)|ensembl:ENST00000265094.9(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007097""(nuclear migration)|go:""GO:0007281""(germ cell development)|go:""GO:0008090""(retrograde axonal transport)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019005""(SCF ubiquitin ligase complex)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0031146""(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0031648""(protein destabilization)|go:""GO:0042753""(positive regulation of circadian rhythm)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0048511""(rhythmic process)|go:""GO:0048854""(brain morphogenesis)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0070840""(dynein complex binding)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|interpro:IPR050995|mint:Q9UKB1|rcsb pdb:6WNX|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_036432.2|refseq:NP_387448.2|refseq:NP_387449.2|efo:""Orphanet:528084""|dip:DIP-27593N|panther:PTHR44129(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:OECIiZL/VFo4L0v4f/KEidvtWuM652616	rogid:8wLc2Pt+mLfRsNwXOnjho+1A0u09606	intact-crc:10E1B3F63DC8FAB2|rigid:Epdxp4QEKu6KRUtYs5nYCZooUWo	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LN28	uniprotkb:P13010	intact:EBI-25401139	intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|ensembl:ENSP00000375977.2|ensembl:ENSP00000375978.3|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1	psi-mi:a0a0h3ln28_mycte(display_long)|uniprotkb:ERDMAN_4222(locus name)	"psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:""X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)""(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401144|imex:IM-27663-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|mint:A0A0H3LN28"	"panther:PTHR12604(orthology-group)|ensembl:ENSG00000079246.16(gene)|ensembl:ENST00000392132.7(transcript)|ensembl:ENST00000392133.7(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000725""(recombinational repair)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000783""(nuclear telomere cap complex)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|refseq:NP_066964.1|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006310""(DNA recombination)|go:""GO:0006974""(DNA damage response)|go:""GO:0007004""(telomere maintenance via telomerase)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022008""(neurogenesis)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032040""(small-subunit processome)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034462""(small-subunit processome assembly)|go:""GO:0034511""(U3 snoRNA binding)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0043564""(""Ku70:Ku80 complex"")|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045027""(DNA end binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0070198""(protein localization to chromosome, telomeric region)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0071398""(cellular response to fatty acid)|go:""GO:0071425""(hematopoietic stem cell proliferation)|go:""GO:0071475""(cellular hyperosmotic salinity response)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0090734""(site of DNA damage)|go:""GO:1904430""(negative regulation of t-circle formation)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7SUD|rcsb pdb:7Z6O|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:7ZT6|rcsb pdb:7ZVT|rcsb pdb:7ZWA|rcsb pdb:7ZYG|rcsb pdb:8AG4|rcsb pdb:8AG5|rcsb pdb:8ASC|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|dip:DIP-31379N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:OECIiZL/VFo4L0v4f/KEidvtWuM652616	rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606	intact-crc:10E1B3F63DC8FAB2|rigid:Epdxp4QEKu6KRUtYs5nYCZooUWo	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LN28	uniprotkb:P12956	intact:EBI-25401139	intact:EBI-353208|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|ensembl:ENSP00000352257.4|ensembl:ENSP00000353192.3|ensembl:ENSP00000384257.1|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8|intact:EBI-21355587	psi-mi:a0a0h3ln28_mycte(display_long)|uniprotkb:ERDMAN_4222(locus name)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401144|imex:IM-27663-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|mint:A0A0H3LN28"	"refseq:NP_001460.1|refseq:NP_001275905.1|ensembl:ENSG00000196419.13(gene)|ensembl:ENST00000359308.8(transcript)|ensembl:ENST00000360079.8(transcript)|ensembl:ENST00000405878.5(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000725""(recombinational repair)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000783""(nuclear telomere cap complex)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006266""(obsolete DNA ligation)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030332""(cyclin binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0043564""(""Ku70:Ku80 complex"")|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045621""(positive regulation of lymphocyte differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0051575""(5'-deoxyribose-5-phosphate lyase activity)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0071475""(cellular hyperosmotic salinity response)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097680""(double-strand break repair via classical nonhomologous end joining)|rcsb pdb:8ASC|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|interpro:IPR047087|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7Z6O|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:7ZT6|rcsb pdb:7ZVT|rcsb pdb:7ZWA|rcsb pdb:7ZYG|rcsb pdb:8AG4|rcsb pdb:8AG5|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|refseq:NP_001275906.1|dip:DIP-24188N|panther:PTHR12604(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:OECIiZL/VFo4L0v4f/KEidvtWuM652616	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	intact-crc:10E1B3F63DC8FAB2|rigid:Epdxp4QEKu6KRUtYs5nYCZooUWo	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LN28	uniprotkb:P84243	intact:EBI-25401139	intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810.3|ensembl:ENSP00000355778.1|ensembl:ENSP00000355780.3|ensembl:ENSP00000355781.1|ensembl:ENSP00000465813.1|ensembl:ENSP00000466020.1|ensembl:ENSP00000468714.1|ensembl:ENSP00000499275.1|ensembl:ENSP00000499385.1|ensembl:ENSP00000499800.1	psi-mi:a0a0h3ln28_mycte(display_long)|uniprotkb:ERDMAN_4222(locus name)	psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401144|imex:IM-27663-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|mint:A0A0H3LN28"	"refseq:NP_002098.1|refseq:NP_005315.1|dip:DIP-40046N|ensembl:ENSG00000132475.10(gene)|ensembl:ENSG00000163041.13(gene)|ensembl:ENST00000254810.8(transcript)|ensembl:ENST00000366813.1(transcript)|ensembl:ENST00000366815.10(transcript)|ensembl:ENST00000366816.5(transcript)|ensembl:ENST00000586607.5(transcript)|ensembl:ENST00000587560.5(transcript)|ensembl:ENST00000589599.5(transcript)|ensembl:ENST00000655399.1(transcript)|ensembl:ENST00000661429.1(transcript)|ensembl:ENST00000666609.1(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000786""(nucleosome)|go:""GO:0000939""(inner kinetochore)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0001556""(oocyte maturation)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001740""(Barr body)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006997""(nucleus organization)|go:""GO:0007286""(spermatid development)|go:""GO:0007338""(single fertilization)|go:""GO:0007566""(embryo implantation)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008584""(male gonad development)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030527""(structural constituent of chromatin)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0031508""(pericentric heterochromatin formation)|go:""GO:0031509""(subtelomeric heterochromatin formation)|go:""GO:0032200""(telomere organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090230""(regulation of centromere complex assembly)|go:""GO:1902340""(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|rcsb pdb:3QL9|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:3WTP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4GNG|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4U7T|rcsb pdb:4W5A|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7CWH|rcsb pdb:7OKP|rcsb pdb:7V1L|rcsb pdb:7V1M|rcsb pdb:7VCQ|rcsb pdb:7W5M|rcsb pdb:7WBV|rcsb pdb:7WBW|rcsb pdb:7WBX|rcsb pdb:7XSE|rcsb pdb:7XSX|rcsb pdb:7XSZ|rcsb pdb:7XT7|rcsb pdb:7XTD|rcsb pdb:7XTI|rcsb pdb:8JH2|rcsb pdb:8JH3|rcsb pdb:8JH4|rcsb pdb:8KB5|rcsb pdb:9B3P|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-68616|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-9821002|reactome:R-HSA-9821993|reactome:R-HSA-983231|reactome:R-HSA-9841922|reactome:R-HSA-9843940|reactome:R-HSA-9843970|reactome:R-HSA-9845323|panther:PTHR11426(orthology-group)|ensembl:ENSP00000254810.3|ensembl:ENSP00000355778.1|ensembl:ENSP00000355780.3|ensembl:ENSP00000355781.1|ensembl:ENSP00000466020.1|ensembl:ENSP00000468714.1|ensembl:ENSP00000465813.1|ensembl:ENSP00000499800.1|ensembl:ENSP00000499385.1|ensembl:ENSP00000499275.1"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:OECIiZL/VFo4L0v4f/KEidvtWuM652616	rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606	intact-crc:10E1B3F63DC8FAB2|rigid:Epdxp4QEKu6KRUtYs5nYCZooUWo	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LN28	uniprotkb:Q71DI3	intact:EBI-25401139	intact:EBI-750650|uniprotkb:A2BDF6|uniprotkb:A6NFS4|uniprotkb:Q6B053|ensembl:ENSP00000333277.2|ensembl:ENSP00000358154.1|ensembl:ENSP00000385479.1	psi-mi:a0a0h3ln28_mycte(display_long)|uniprotkb:ERDMAN_4222(locus name)	psi-mi:h32_human(display_long)|uniprotkb:H3C13(gene name)|psi-mi:H3C13(display_short)|uniprotkb:H3C14(gene name)|psi-mi:H3C14(display_short)|uniprotkb:H3C15(gene name)|psi-mi:H3C15(display_short)|uniprotkb:H3-clustered histone 13(gene name synonym)|uniprotkb:H3-clustered histone 14(gene name synonym)|uniprotkb:H3-clustered histone 15(gene name synonym)|uniprotkb:H3F2(gene name synonym)|uniprotkb:H3FM(gene name synonym)|uniprotkb:HIST2H3A(gene name synonym)|uniprotkb:HIST2H3C(gene name synonym)|uniprotkb:HIST2H3D(gene name synonym)|uniprotkb:Histone H3/m(gene name synonym)|uniprotkb:Histone H3/o(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401144|imex:IM-27663-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|mint:A0A0H3LN28"	"refseq:NP_001005464.1|refseq:NP_001116847.1|refseq:NP_066403.2|ensembl:ENSG00000183598.4(gene)|ensembl:ENSG00000203811.2(gene)|ensembl:ENSG00000203852.4(gene)|ensembl:ENST00000331491.2(transcript)|ensembl:ENST00000369158.2(transcript)|ensembl:ENST00000403683.2(transcript)|go:""GO:0000786""(nucleosome)|go:""GO:0003677""(DNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0030527""(structural constituent of chromatin)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q71DI3|rcsb pdb:2IIJ|rcsb pdb:2X4W|rcsb pdb:2X4X|rcsb pdb:2X4Y|rcsb pdb:3AV1|rcsb pdb:3DB3|rcsb pdb:3MO8|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:4OUC|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B40|rcsb pdb:5BO0|rcsb pdb:5CIU|rcsb pdb:5VAC|rcsb pdb:6ACE|rcsb pdb:6FML|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7BQZ|rcsb pdb:7BU9|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7PET|rcsb pdb:7PEU|rcsb pdb:7PEV|rcsb pdb:7PEW|rcsb pdb:7PEX|rcsb pdb:7PEY|rcsb pdb:7PEZ|rcsb pdb:7PF0|rcsb pdb:7PF2|rcsb pdb:7PF3|rcsb pdb:7PF4|rcsb pdb:7PF5|rcsb pdb:7PF6|rcsb pdb:7PFA|rcsb pdb:7PFC|rcsb pdb:7PFD|rcsb pdb:7PFE|rcsb pdb:7PFF|rcsb pdb:7PFT|rcsb pdb:7PFU|rcsb pdb:7PFV|rcsb pdb:7PFW|rcsb pdb:7PFX|rcsb pdb:7TAN|rcsb pdb:7U50|rcsb pdb:7U51|rcsb pdb:7U52|rcsb pdb:7U53|rcsb pdb:7UV9|rcsb pdb:7UVA|rcsb pdb:7XCR|rcsb pdb:7XCT|rcsb pdb:7XD0|rcsb pdb:7YRD|rcsb pdb:8AAG|rcsb pdb:8ATF|rcsb pdb:8AV6|rcsb pdb:8GRQ|rcsb pdb:8HQY|rcsb pdb:8HR1|rcsb pdb:8JLB|rcsb pdb:8JLD|rcsb pdb:8OL1|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-68616|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-9821002|reactome:R-HSA-983231|reactome:R-HSA-9841922|reactome:R-HSA-9843940|reactome:R-HSA-9843970|reactome:R-HSA-9845323|dip:DIP-48606N|panther:PTHR11426(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:OECIiZL/VFo4L0v4f/KEidvtWuM652616	rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o9606	intact-crc:10E1B3F63DC8FAB2|rigid:Epdxp4QEKu6KRUtYs5nYCZooUWo	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LEM1	uniprotkb:Q9H773	intact:EBI-25401166	intact:EBI-723569|intact:EBI-1384169|ensembl:ENSP00000322524.4	psi-mi:a0a0h3lem1_mycte(display_long)|uniprotkb:esxQ(gene name)|psi-mi:esxQ(display_short)|uniprotkb:ERDMAN_3306(locus name)	psi-mi:dctp1_human(display_long)|uniprotkb:DCTPP1(gene name)|psi-mi:DCTPP1(display_short)|uniprotkb:RS21C6(gene name synonym)|uniprotkb:CDA03(orf name)|uniprotkb:XTP3TPA(gene name synonym)|uniprotkb:Deoxycytidine-triphosphatase 1(gene name synonym)|uniprotkb:XTP3-transactivated gene A protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401172|imex:IM-27663-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR036689|mint:A0A0H3LEM1	"refseq:NP_077001.1|ensembl:ENSG00000179958.10(gene)|ensembl:ENST00000319285.5(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006253""(dCTP catabolic process)|go:""GO:0009143""(nucleoside triphosphate catabolic process)|go:""GO:0032556""(pyrimidine deoxyribonucleotide binding)|go:""GO:0042262""(DNA protection)|go:""GO:0042802""(identical protein binding)|go:""GO:0047429""(nucleoside triphosphate diphosphatase activity)|go:""GO:0047840""(dCTP diphosphatase activity)|interpro:IPR025984|interpro:IPR052555|mint:Q9H773|rcsb pdb:7MU5|reactome:R-HSA-499943|panther:PTHR46523(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:wCHe508qlgi/G9AS2PozpADMTog652616	rogid:4EfV2ZU2MgDiFXShthfualZnat09606	intact-crc:04AEB05961E6AA38|rigid:+y6KqYLCvcj9DwbPa2aac39kMAk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LEM1	uniprotkb:Q86Y56	intact:EBI-25401166	intact:EBI-719966|uniprotkb:Q69YL1|uniprotkb:Q96FI9|uniprotkb:Q9NX75|ensembl:ENSP00000297440.6	psi-mi:a0a0h3lem1_mycte(display_long)|uniprotkb:esxQ(gene name)|psi-mi:esxQ(display_short)|uniprotkb:ERDMAN_3306(locus name)	psi-mi:daaf5_human(display_long)|uniprotkb:DNAAF5(gene name)|psi-mi:DNAAF5(display_short)|uniprotkb:HEAT repeat-containing protein 2(gene name synonym)|uniprotkb:HEATR2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401172|imex:IM-27663-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR036689|mint:A0A0H3LEM1	"efo:""Orphanet:244""|ensembl:ENSG00000164818.16(gene)|ensembl:ENST00000297440.11(transcript)|go:""GO:0003341""(cilium movement)|go:""GO:0005737""(cytoplasm)|go:""GO:0036158""(outer dynein arm assembly)|go:""GO:0036159""(inner dynein arm assembly)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0120293""(dynein axonemal particle)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR052623|mint:Q86Y56|refseq:NP_060272.3|panther:PTHR16216(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:wCHe508qlgi/G9AS2PozpADMTog652616	rogid:5AmIkT2NW1/GyC8udQmrI5hRAsU9606	intact-crc:04AEB05961E6AA38|rigid:+y6KqYLCvcj9DwbPa2aac39kMAk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LEM1	uniprotkb:Q92616	intact:EBI-25401166	intact:EBI-356221|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692|ensembl:ENSP00000300648.6	psi-mi:a0a0h3lem1_mycte(display_long)|uniprotkb:esxQ(gene name)|psi-mi:esxQ(display_short)|uniprotkb:ERDMAN_3306(locus name)	psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401172|imex:IM-27663-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR036689|mint:A0A0H3LEM1	"refseq:NP_006827.1|ensembl:ENSG00000089154.11(gene)|ensembl:ENST00000300648.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0006417""(regulation of translation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016020""(membrane)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0055106""(ubiquitin-protein transferase regulator activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0140469""(GCN2-mediated signaling)|go:""GO:0160127""(protein-RNA covalent cross-linking repair)|go:""GO:0170011""(stalled ribosome sensor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|panther:PTHR23346(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:wCHe508qlgi/G9AS2PozpADMTog652616	rogid:aXrR83M54Nh1pnmdgL71NurSSfI9606	intact-crc:04AEB05961E6AA38|rigid:+y6KqYLCvcj9DwbPa2aac39kMAk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LEM1	uniprotkb:Q9H3P7	intact:EBI-25401166	intact:EBI-1791792|ensembl:ENSP00000355777.5|uniprotkb:Q5VTJ0|uniprotkb:Q6P9F1|uniprotkb:Q8IZC5|uniprotkb:Q8N4D6|uniprotkb:Q9H6U3|uniprotkb:B2RB29	psi-mi:a0a0h3lem1_mycte(display_long)|uniprotkb:esxQ(gene name)|psi-mi:esxQ(display_short)|uniprotkb:ERDMAN_3306(locus name)	psi-mi:gcp60_human(display_long)|uniprotkb:GOCAP1(gene name synonym)|uniprotkb:GOLPH1(gene name synonym)|uniprotkb:ACBD3(gene name)|psi-mi:ACBD3(display_short)|uniprotkb:GCP60(gene name synonym)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401172|imex:IM-27663-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR036689|mint:A0A0H3LEM1	"ensembl:ENSG00000182827.9(gene)|ensembl:ENST00000366812.6(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006694""(steroid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR009038(GOLD)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|interpro:IPR036598|interpro:IPR052269|mint:Q9H3P7|rcsb pdb:2N72|rcsb pdb:2N73|rcsb pdb:5LZ1|rcsb pdb:5LZ3|rcsb pdb:5LZ6|rcsb pdb:5TDQ|rcsb pdb:6HLN|rcsb pdb:6HLT|rcsb pdb:6HLV|rcsb pdb:6HLW|rcsb pdb:6HM8|rcsb pdb:6HMV|reactome:R-HSA-432722|refseq:NP_073572.2|dip:DIP-40673N|panther:PTHR22973(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:wCHe508qlgi/G9AS2PozpADMTog652616	rogid:jAaMXnoXG6RGj+lAgIYk1inXA6o9606	intact-crc:04AEB05961E6AA38|rigid:+y6KqYLCvcj9DwbPa2aac39kMAk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q9UKV8	intact:EBI-25401182	intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592.5	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:5JS2|rcsb pdb:5KI6|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|rcsb pdb:7KI3|rcsb pdb:8D6J|rcsb pdb:8D71|rcsb pdb:8THQ|rcsb pdb:9BEZ|rcsb pdb:9BF0|rcsb pdb:9BF2|ensembl:ENSG00000123908.12(gene)|ensembl:ENST00000220592.10(transcript)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000932""(P-body)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010501""(obsolete RNA secondary structure unwinding)|go:""GO:0010586""(miRNA metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016442""(RISC complex)|go:""GO:0030422""(siRNA processing)|go:""GO:0030425""(dendrite)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031054""(pre-miRNA processing)|go:""GO:0033962""(P-body assembly)|go:""GO:0035194""(regulatory ncRNA-mediated post-transcriptional gene silencing)|go:""GO:0035196""(miRNA processing)|go:""GO:0035197""(siRNA binding)|go:""GO:0035198""(miRNA binding)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0035279""(miRNA-mediated gene silencing by mRNA destabilization)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042985""(negative regulation of amyloid precursor protein biosynthetic process)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0070551""(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:""GO:0070578""(RISC-loading complex)|go:""GO:0070922""(RISC complex assembly)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090624""(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:""GO:0090625""(siRNA-mediated gene silencing by mRNA destabilization)|go:""GO:0098794""(postsynapse)|go:""GO:0098808""(mRNA cap binding)|go:""GO:0098978""(glutamatergic synapse)|reactome:R-HSA-1912408|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901165""(positive regulation of trophoblast cell migration)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|interpro:IPR045246|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|rcsb pdb:3QX9|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9725371|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9820841|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001158095.1|refseq:NP_036286.2|dip:DIP-29194N|efo:""Orphanet:528084""|panther:PTHR22891(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q6Y7W6	intact:EBI-25401182	intact:EBI-765394|uniprotkb:O75137|uniprotkb:Q7Z2Z8|uniprotkb:Q7Z3I2|uniprotkb:Q96HU4|uniprotkb:Q9NV82|ensembl:ENSP00000362664.5|ensembl:ENSP00000386537.1|uniprotkb:B9EG55|uniprotkb:A6H8W4|uniprotkb:E9PBB0|intact:EBI-10969943	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:ggyf2_human(display_long)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"ensembl:ENSG00000204120.16(gene)|ensembl:ENST00000373563.9(transcript)|ensembl:ENST00000409547.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007631""(feeding behavior)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016441""(post-transcriptional gene silencing)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0021522""(spinal cord motor neuron differentiation)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0043204""(perikaryon)|go:""GO:0045296""(cadherin binding)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050881""(musculoskeletal movement)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0061157""(mRNA destabilization)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:1990635""(proximal dendrite)|interpro:IPR003169(GYF)|interpro:IPR035445|interpro:IPR051640|mint:Q6Y7W6|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:7RUP|refseq:NP_001096616.1|refseq:NP_001096617.1|refseq:NP_001096618.1|refseq:NP_056390.2|efo:""Orphanet:411602""|panther:PTHR14445(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q9H9C1	intact:EBI-25401182	intact:EBI-749080|uniprotkb:O95434|uniprotkb:Q9H7E1|uniprotkb:Q9H9I9|uniprotkb:B4DPI6|ensembl:ENSP00000339122.2|ensembl:ENSP00000452181.1|ensembl:ENSP00000452191.1	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:spe39_human(display_long)|uniprotkb:VIPAS39(gene name)|psi-mi:VIPAS39(display_short)|uniprotkb:C14orf133(gene name synonym)|uniprotkb:SPE39(gene name synonym)|uniprotkb:VIPAR(gene name synonym)|uniprotkb:VPS33B-interacting protein in apical-basolateral polarity regulator(gene name synonym)|uniprotkb:VPS33B-interacting protein in polarity and apical restriction(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"efo:""Orphanet:2697""|ensembl:ENSG00000151445.16(gene)|ensembl:ENST00000343765.6(transcript)|ensembl:ENST00000553888.5(transcript)|ensembl:ENST00000557658.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007034""(vacuolar transport)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0017185""(peptidyl-lysine hydroxylation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0032963""(collagen metabolic process)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046907""(intracellular transport)|go:""GO:0055037""(recycling endosome)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0099023""(vesicle tethering complex)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR038132|interpro:IPR040057|mint:Q9H9C1|refseq:NP_001180243.1|refseq:NP_001180244.1|refseq:NP_001180245.1|refseq:NP_001180246.1|refseq:NP_071350.2|panther:PTHR13364(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:Th3K4elgRIPP7DHwIRBN+GKNOXM9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q8NBJ5	intact:EBI-25401182	intact:EBI-1057068|uniprotkb:Q8NC64|ensembl:ENSP00000252599.3	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	"psi-mi:gt251_human(display_long)|uniprotkb:COLGALT1(gene name)|psi-mi:COLGALT1(display_short)|uniprotkb:""Collagen beta(1-O)galactosyltransferase 1""(gene name synonym)|uniprotkb:GLT25D1(gene name synonym)|uniprotkb:Glycosyltransferase 25 family member 1(gene name synonym)|uniprotkb:Hydroxylysine galactosyltransferase 1(gene name synonym)|uniprotkb:PSEC0241(orf name)"	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"ensembl:ENSG00000130309.12(gene)|ensembl:ENST00000252599.9(transcript)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0016020""(membrane)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0050211""(procollagen galactosyltransferase activity)|go:""GO:1904028""(positive regulation of collagen fibril organization)|interpro:IPR002654(Glycosyl transferase, family 25)|interpro:IPR029044|interpro:IPR050757|mint:Q8NBJ5|reactome:R-HSA-1650814|refseq:NP_078932.2|efo:""Orphanet:99810""|panther:PTHR10730(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:nB7wFmsUKfA2+PrPaqw08fQpJRs9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q9UPQ9	intact:EBI-25401182	intact:EBI-947158|uniprotkb:B0QY78|uniprotkb:Q5TH52|uniprotkb:Q8TBX2|uniprotkb:B4DGC0|uniprotkb:B0QY73|ensembl:ENSP00000401946.2	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:tnr6b_human(display_long)|uniprotkb:TNRC6B(gene name)|psi-mi:TNRC6B(display_short)|uniprotkb:KIAA1093(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"ensembl:ENSG00000100354.22(gene)|ensembl:ENST00000454349.7(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034925|interpro:IPR035979|interpro:IPR052068|mint:Q9UPQ9|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001020014.1|refseq:NP_001155973.1|refseq:NP_055903.2|dip:DIP-29624N|efo:""Orphanet:528084""|panther:PTHR13020(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:A4yGG9Gt++0QN+6jFzfhWVYN+Dw9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q7Z7F0	intact:EBI-25401182	intact:EBI-751942|uniprotkb:O94981|uniprotkb:Q7L7Q2|uniprotkb:Q7Z7E9|uniprotkb:Q8TBQ0|ensembl:ENSP00000357304.3	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:khdc4_human(display_long)|uniprotkb:KHDC4(gene name)|psi-mi:KHDC4(display_short)|uniprotkb:BLOM7(gene name synonym)|uniprotkb:Brings lots of money 7(gene name synonym)|uniprotkb:KIAA0907(gene name synonym)|uniprotkb:Pre-mRNA splicing factor protein KHDC4(gene name synonym)|uniprotkb:SNORA80EHG(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_055764.2|ensembl:ENSG00000132680.11(gene)|ensembl:ENST00000368321.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006376""(mRNA splice site recognition)|interpro:IPR031121|interpro:IPR036612|interpro:IPR047889|interpro:IPR047890|interpro:IPR055256|mint:Q7Z7F0|rcsb pdb:2YQR|panther:PTHR15744(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:JjYHRjwyj+jqt/m4RFA7bwsWEOY9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q9H267	intact:EBI-25401182	intact:EBI-749072|uniprotkb:Q96K14|uniprotkb:Q9NRP6|uniprotkb:Q9NSF3|ensembl:ENSP00000327650.4|uniprotkb:B3KQF6	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:vp33b_human(display_long)|uniprotkb:VPS33B(gene name)|psi-mi:VPS33B(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"ensembl:ENSG00000184056.15(gene)|ensembl:ENST00000333371.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007032""(endosome organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0017185""(peptidyl-lysine hydroxylation)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030897""(HOPS complex)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032400""(melanosome localization)|go:""GO:0032418""(lysosome localization)|go:""GO:0032963""(collagen metabolic process)|go:""GO:0033263""(CORVET complex)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0061025""(membrane fusion)|go:""GO:0070889""(platelet alpha granule organization)|go:""GO:0090330""(regulation of platelet aggregation)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0099023""(vesicle tethering complex)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q9H267|reactome:R-HSA-9636383|reactome:R-HSA-9754560|refseq:NP_001276077.1|refseq:NP_001276078.1|refseq:NP_061138.3|refseq:XP_005254944.1|refseq:XP_011519750.1|efo:""Orphanet:2697""|panther:PTHR11679(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:T2rUOt9qjfn8vCzySAKCCa3UC689606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:O60568	intact:EBI-25401182	intact:EBI-741582|uniprotkb:Q540C3|uniprotkb:B2R6W6|ensembl:ENSP00000223127.3	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:plod3_human(display_long)|uniprotkb:PLOD3(gene name)|psi-mi:PLOD3(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"ensembl:ENSG00000106397.12(gene)|ensembl:ENST00000223127.8(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001886""(endothelial cell morphogenesis)|go:""GO:0005506""(iron ion binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0006493""(protein O-linked glycosylation)|go:""GO:0008104""(protein localization)|go:""GO:0008475""(procollagen-lysine 5-dioxygenase activity)|go:""GO:0017185""(peptidyl-lysine hydroxylation)|go:""GO:0021915""(neural tube development)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0031418""(L-ascorbic acid binding)|go:""GO:0032963""(collagen metabolic process)|go:""GO:0033823""(procollagen glucosyltransferase activity)|go:""GO:0036094""(small molecule binding)|go:""GO:0042311""(vasodilation)|go:""GO:0046872""(metal ion binding)|go:""GO:0046947""(hydroxylysine biosynthetic process)|go:""GO:0048730""(epidermis morphogenesis)|go:""GO:0050211""(procollagen galactosyltransferase activity)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070831""(basement membrane assembly)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123(""2OG-Fe(II) oxygenase"")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|interpro:IPR044861|interpro:IPR050757|mint:O60568|rcsb pdb:6FXK|rcsb pdb:6FXM|rcsb pdb:6FXR|rcsb pdb:6FXT|rcsb pdb:6FXX|rcsb pdb:6FXY|rcsb pdb:6TE3|rcsb pdb:6TEC|rcsb pdb:6TES|rcsb pdb:6TEU|rcsb pdb:6TEX|rcsb pdb:6TEZ|rcsb pdb:6WFV|rcsb pdb:8ONE|reactome:R-HSA-1650814|refseq:NP_001075.1|efo:""Orphanet:300284""|panther:PTHR10730(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:dvfk+ko7squrB6c4AayW+fR8EnE9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q9NXV2	intact:EBI-25401182	intact:EBI-1056857|uniprotkb:D3DU96|ensembl:ENSP00000301738.4	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:kctd5_human(display_long)|uniprotkb:KCTD5(gene name)|psi-mi:KCTD5(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_061865.1|ensembl:ENSG00000167977.9(gene)|ensembl:ENST00000301738.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0097602""(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q9NXV2|rcsb pdb:3DRX|rcsb pdb:3DRY|rcsb pdb:3DRZ|rcsb pdb:8U7Z|rcsb pdb:8U80|rcsb pdb:8U81|rcsb pdb:8U82|rcsb pdb:8U83|rcsb pdb:8U84|panther:PTHR14958(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:KzXA4jgTKUY/EE1ORX+nMLCPfro9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:O95466	intact:EBI-25401182	intact:EBI-720020|uniprotkb:Q6DKG5|uniprotkb:Q6IBP3|uniprotkb:Q86UH1|uniprotkb:Q8N671|uniprotkb:Q8TDH1|uniprotkb:Q96H10|uniprotkb:D2DGW2|ensembl:ENSP00000329219.2	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:fmnl1_human(display_long)|uniprotkb:Leukocyte formin(gene name synonym)|uniprotkb:CLL-associated antigen KW-13(gene name synonym)|uniprotkb:FMNL1(gene name)|psi-mi:FMNL1(display_short)|uniprotkb:C17orf1(gene name synonym)|uniprotkb:C17orf1B(gene name synonym)|uniprotkb:FMNL(gene name synonym)|uniprotkb:FRL1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_005883.2|ensembl:ENSG00000184922.15(gene)|ensembl:ENST00000331495.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032059""(bleb)|go:""GO:0032794""(GTPase activating protein binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR043592|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:O95466|rcsb pdb:4YDH|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:XP_006722126.1|refseq:XP_006722133.1|panther:PTHR45857(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:SN1xgeqb5yPUjiaEv2H/kyDrD4c9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:P11586	intact:EBI-25401182	intact:EBI-709638|uniprotkb:Q86VC9|uniprotkb:Q9BVP5|uniprotkb:B2R5Y2|uniprotkb:G3V2B8|ensembl:ENSP00000498336.1|ensembl:ENSP00000498511.1|intact:EBI-21358459|uniprotkb:A0A024R652|uniprotkb:A0A384N5Y3	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:c1tc_human(display_long)|uniprotkb:MTHFD1(gene name)|psi-mi:MTHFD1(display_short)|uniprotkb:MTHFC(gene name synonym)|uniprotkb:MTHFD(gene name synonym)|uniprotkb:Epididymis secretory sperm binding protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"efo:""Orphanet:658813""|dip:DIP-33682N|ensembl:ENSG00000100714.18(gene)|ensembl:ENST00000651537.1(transcript)|ensembl:ENST00000652337.1(transcript)|go:""GO:0001780""(neutrophil homeostasis)|go:""GO:0001843""(neural tube closure)|go:""GO:0004329""(formate-tetrahydrofolate ligase activity)|go:""GO:0004477""(methenyltetrahydrofolate cyclohydrolase activity)|go:""GO:0004486""(""methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity"")|go:""GO:0004487""(""methylenetetrahydrofolate dehydrogenase (NAD+) activity"")|go:""GO:0004488""(""methylenetetrahydrofolate dehydrogenase (NADP+) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006555""(methionine metabolic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0007507""(heart development)|go:""GO:0009069""(serine family amino acid metabolic process)|go:""GO:0009070""(serine family amino acid biosynthetic process)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0009152""(purine ribonucleotide biosynthetic process)|go:""GO:0009257""(10-formyltetrahydrofolate biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019346""(transsulfuration)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0048702""(embryonic neurocranium morphogenesis)|go:""GO:0048703""(embryonic viscerocranium morphogenesis)|go:""GO:0061053""(somite development)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR020867|interpro:IPR027417|interpro:IPR036291|interpro:IPR046346|mint:P11586|rcsb pdb:1A4I|rcsb pdb:1DIA|rcsb pdb:1DIB|rcsb pdb:1DIG|rcsb pdb:6ECP|rcsb pdb:6ECQ|rcsb pdb:6ECR|reactome:R-HSA-196757|refseq:NP_005947.3|panther:PTHR48099(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:6ZizfpjVcaL5WNxKXL7qJpw59PI9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q96HE7	intact:EBI-25401182	intact:EBI-2564539|uniprotkb:A8K9X4|uniprotkb:A8MYW1|uniprotkb:Q7LD45|uniprotkb:Q9P1Q9|uniprotkb:Q9UKV6|ensembl:ENSP00000379042.3	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:ero1a_human(display_long)|uniprotkb:ERO1A(gene name)|psi-mi:ERO1A(display_short)|uniprotkb:ERO1L(gene name synonym)|uniprotkb:Endoplasmic oxidoreductin-1-like protein(gene name synonym)|uniprotkb:Endoplasmic reticulum oxidoreductase alpha(gene name synonym)|uniprotkb:Oxidoreductin-1-L-alpha(gene name synonym)|uniprotkb:UNQ434/PRO865(orf name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_055399.1|ensembl:ENSG00000197930.13(gene)|ensembl:ENST00000395686.8(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005796""(Golgi lumen)|go:""GO:0006457""(protein folding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0009266""(response to temperature stimulus)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0016020""(membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016972""(thiol oxidase activity)|go:""GO:0019852""(L-ascorbic acid metabolic process)|go:""GO:0022417""(obsolete protein maturation by protein folding)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030425""(dendrite)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036211""(protein modification process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0050873""(brown fat cell differentiation)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071949""(FAD binding)|interpro:IPR007266(Endoplasmic reticulum oxidoreductin 1)|interpro:IPR037192|mint:Q96HE7|rcsb pdb:3AHQ|rcsb pdb:3AHR|reactome:R-HSA-3299685|panther:PTHR12613(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:7IOP99IQt+7MBAQ0LKqPo5mFylo9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q7Z739	intact:EBI-25401182	intact:EBI-2849837|uniprotkb:Q659A3|uniprotkb:B3KXL4|uniprotkb:Q63Z37|ensembl:ENSP00000473496.2	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:ythd3_human(display_long)|uniprotkb:YTHDF3(gene name)|psi-mi:YTHDF3(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_689971.4|refseq:NP_001264742.1|refseq:NP_001264743.1|refseq:NP_001264744.1|refseq:NP_001264745.1|refseq:NP_001264746.1|refseq:NP_001264747.1|ensembl:ENSG00000185728.17(gene)|ensembl:ENST00000539294.6(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0034063""(stress granule assembly)|go:""GO:0043022""(ribosome binding)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0061157""(mRNA destabilization)|go:""GO:0070925""(organelle assembly)|go:""GO:1901163""(regulation of trophoblast cell migration)|go:""GO:1990247""(N6-methyladenosine-containing RNA reader activity)|interpro:IPR007275(YT521-B-like protein)|interpro:IPR045168|mint:Q7Z739|rcsb pdb:6ZOT|rcsb pdb:8BS5|rcsb pdb:8BS6|panther:PTHR12357(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:M1/1RMOQiQ7kD+J9KMmEq9RZebw9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q15637	intact:EBI-25401182	intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607.3	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|refseq:XP_016873733.1|refseq:NP_973726.2|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N|ensembl:ENSG00000168066.22(gene)|ensembl:ENST00000377390.8(transcript)|go:""GO:0000245""(spliceosomal complex assembly)|go:""GO:0000389""(mRNA 3'-splice site recognition)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005840""(ribosome)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016604""(nuclear body)|go:""GO:0030238""(male sex determination)|go:""GO:0030575""(nuclear body organization)|go:""GO:0033327""(Leydig cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0048662""(negative regulation of smooth muscle cell proliferation)|go:""GO:0050810""(regulation of steroid biosynthetic process)|go:""GO:0089701""(U2AF complex)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR032570|interpro:IPR036612|interpro:IPR045071|interpro:IPR047086|interpro:IPR055256|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|rcsb pdb:4FXW|rcsb pdb:4FXX|rcsb pdb:7VH9|rcsb pdb:7VPX|rcsb pdb:8PXX|reactome:R-HSA-72163|panther:PTHR11208(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:A6NJG2	intact:EBI-25401182	intact:EBI-25401233|ensembl:ENSP00000340975.3	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:swahd_human(display_long)|uniprotkb:Ankyrin repeat domain-containing protein 58(gene name synonym)|uniprotkb:Protein sosondowah homolog D(gene name synonym)|uniprotkb:SOWAHD(gene name)|psi-mi:SOWAHD(display_short)|uniprotkb:ANKRD58(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	ensembl:ENSG00000187808.5(gene)|ensembl:ENST00000343905.5(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:A6NJG2|panther:PTHR14491(orthology-group)|refseq:NP_001099046.1	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:Rx0hoh5SFRSjD0DzfhznneVtTOA9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q6P3W7	intact:EBI-25401182	intact:EBI-1046810|ensembl:ENSP00000354061.2|uniprotkb:Q96EF4|uniprotkb:Q96ST4|uniprotkb:Q9H7V5|uniprotkb:Q9NVH3|uniprotkb:Q9P2I7|uniprotkb:A8KAB5	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:scyl2_human(display_long)|uniprotkb:Coated vesicle-associated kinase of 104 kDa(gene name synonym)|uniprotkb:SCYL2(gene name)|psi-mi:SCYL2(display_short)|uniprotkb:CVAK104(gene name synonym)|uniprotkb:KIAA1360(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"ensembl:ENSG00000136021.19(gene)|ensembl:ENST00000360820.7(transcript)|go:""GO:0004672""(protein kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0007420""(brain development)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0021860""(pyramidal neuron development)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR051177|mint:Q6P3W7|refseq:NP_001304713.1|refseq:NP_001317182.1|refseq:NP_001317183.1|refseq:NP_001317185.1|refseq:NP_060458.3|efo:""Orphanet:1143""|panther:PTHR12984(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:gYSfjHA8PY8nvLrWxnm2RxpNdnY9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q92499	intact:EBI-25401182	intact:EBI-358474|ensembl:ENSP00000233084.3|ensembl:ENSP00000370745.1|ensembl:ENSP00000413767.2|ensembl:ENSP00000504080.1|uniprotkb:B4DME8|uniprotkb:B4DPN6	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:ddx1_human(display_long)|uniprotkb:DDX1(gene name)|psi-mi:DDX1(display_short)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:DEAD box protein retinoblastoma(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_004930.1|ensembl:ENSG00000079785.16(gene)|ensembl:ENST00000233084.8(transcript)|ensembl:ENST00000381341.7(transcript)|ensembl:ENST00000434671.2(transcript)|ensembl:ENST00000677302.1(transcript)|go:""GO:0000245""(spliceosomal complex assembly)|go:""GO:0002735""(positive regulation of myeloid dendritic cell cytokine production)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006388""(tRNA splicing, via endonucleolytic cleavage and ligation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0033677""(DNA/RNA helicase activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0045087""(innate immune response)|go:""GO:0051607""(defense response to virus)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071920""(cleavage body)|go:""GO:0072669""(tRNA-splicing ligase complex)|go:""GO:0090304""(nucleic acid metabolic process)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR043136|mint:Q92499|rcsb pdb:4XW3|rcsb pdb:8TBX|reactome:R-HSA-6784531|dip:DIP-38163N|panther:PTHR24031(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:n2Zv07BpuUDT32/ttDzIFXH3yIQ9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:O60879	intact:EBI-25401182	intact:EBI-2835047|ensembl:ENSP00000321348.8|uniprotkb:O60878|uniprotkb:Q9UJL2|uniprotkb:Q8WX06|uniprotkb:Q8WX48|uniprotkb:A6NG19	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:diap2_human(display_long)|uniprotkb:DIAPH2(gene name)|psi-mi:DIAPH2(display_short)|uniprotkb:DIA(gene name synonym)|uniprotkb:Diaphanous-related formin-2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"ensembl:ENSG00000147202.19(gene)|ensembl:ENST00000324765.13(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0007292""(female gamete generation)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048477""(oogenesis)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|interpro:IPR044933|interpro:IPR051412|mint:O60879|reactome:R-HSA-5663220|reactome:R-HSA-9013405|reactome:R-HSA-9035034|dip:DIP-47261N|refseq:NP_006720.1|refseq:NP_009293.1|panther:PTHR45691(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:y/mru/1w3z/4Dn1K++ya3k80Qzs9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q9Y224	intact:EBI-25401182	intact:EBI-1104547|ensembl:ENSP00000261700.3	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_057123.1|ensembl:ENSG00000087302.9(gene)|ensembl:ENST00000261700.8(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006388""(tRNA splicing, via endonucleolytic cleavage and ligation)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050658""(RNA transport)|go:""GO:0072669""(tRNA-splicing ligase complex)|go:""GO:0072686""(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|rcsb pdb:7P3A|reactome:R-HSA-6784531|panther:PTHR15924(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:P22681	intact:EBI-25401182	intact:EBI-518228|uniprotkb:A3KMP8|ensembl:ENSP00000264033.3	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:cbl_human(display_long)|uniprotkb:Signal transduction protein CBL(gene name synonym)|uniprotkb:Proto-oncogene c-Cbl(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)|uniprotkb:RING finger protein 55(gene name synonym)|uniprotkb:CBL(gene name)|psi-mi:CBL(display_short)|uniprotkb:CBL2(gene name synonym)|uniprotkb:RNF55(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"efo:""Orphanet:363972""|efo:""Orphanet:648""|efo:""Orphanet:86834""|efo:""Orphanet:98850""|ensembl:ENSG00000110395.8(gene)|ensembl:ENST00000264033.6(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0008584""(male gonad development)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0014823""(response to activity)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016600""(flotillin complex)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0030426""(growth cone)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0032487""(regulation of Rap protein signal transduction)|go:""GO:0033574""(response to testosterone)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036312""(phosphatidylinositol 3-kinase regulatory subunit binding)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042594""(response to starvation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043303""(mast cell degranulation)|go:""GO:0045121""(membrane raft)|go:""GO:0045296""(cadherin binding)|go:""GO:0045471""(response to ethanol)|go:""GO:0045742""(positive regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070086""(ubiquitin-dependent endocytosis)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:2000583""(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR009060(UBA-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018957|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|rcsb pdb:6O03|interpro:IPR036860|mint:P22681|rcsb pdb:1B47|rcsb pdb:1FBV|rcsb pdb:1YVH|rcsb pdb:2CBL|rcsb pdb:2JUJ|rcsb pdb:2K4D|rcsb pdb:2OO9|rcsb pdb:2Y1M|rcsb pdb:2Y1N|rcsb pdb:3BUM|rcsb pdb:3BUN|rcsb pdb:3BUO|rcsb pdb:3BUW|rcsb pdb:3BUX|rcsb pdb:3OB1|rcsb pdb:3OB2|rcsb pdb:3PLF|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4GPL|rcsb pdb:5HKW|rcsb pdb:5HKX|rcsb pdb:5HKY|rcsb pdb:5HKZ|rcsb pdb:5HL0|rcsb pdb:5J3X|rcsb pdb:5O76|rcsb pdb:6O02|rcsb pdb:6XAR|rcsb pdb:7SIY|reactome:R-HSA-1059683|reactome:R-HSA-1236382|reactome:R-HSA-1295596|reactome:R-HSA-1433559|reactome:R-HSA-182971|reactome:R-HSA-2173789|reactome:R-HSA-5637810|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6807004|reactome:R-HSA-8849469|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-912631|reactome:R-HSA-9680350|reactome:R-HSA-9706369|reactome:R-HSA-9706377|refseq:NP_005179.2|dip:DIP-189N|panther:PTHR23007(orthology-group)|ensembl:ENSP00000264033.3"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:WPXFRmBKHEANKUlN/OYsuyAe9a09606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q9Y3I0	intact:EBI-25401182	intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038.5	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_055121.1|panther:PTHR11118(orthology-group)|dip:DIP-46750N|ensembl:ENSG00000100220.12(gene)|ensembl:ENST00000216038.6(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001890""(placenta development)|go:""GO:0003723""(RNA binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006388""(tRNA splicing, via endonucleolytic cleavage and ligation)|go:""GO:0017166""(vinculin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0072669""(tRNA-splicing ligase complex)|go:""GO:0170057""(""RNA ligase (GTP) activity"")|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|rcsb pdb:7P3B|rcsb pdb:8BTT|rcsb pdb:8ODO|rcsb pdb:8ODP|reactome:R-HSA-6784531"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q99613	intact:EBI-25401182	intact:EBI-353741|uniprotkb:A8K7Z0|ensembl:ENSP00000332604.7|ensembl:ENSP00000378953.1|ensembl:ENSP00000457418.1|ensembl:ENSP00000457963.1|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-25643229|uniprotkb:B4E1D5|uniprotkb:H3BRV0|intact:EBI-11017021	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|ensembl:ENSG00000184110.15(gene)|ensembl:ENST00000331666.11(transcript)|ensembl:ENST00000395587.5(transcript)|ensembl:ENST00000566501.5(transcript)|ensembl:ENST00000566866.5(transcript)|rcsb pdb:8PJ3|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0043022""(ribosome binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:1902416""(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8RG0|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001273407.1|refseq:NP_001254503.1|dip:DIP-32865N|panther:PTHR13937(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q13148	intact:EBI-25401182	intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|ensembl:ENSP00000240185.4|ensembl:ENSP00000491203.1|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"ensembl:ENSG00000120948.19(gene)|ensembl:ENST00000240185.8(transcript)|ensembl:ENST00000639083.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005726""(perichromatin fibrils)|go:""GO:0005739""(mitochondrion)|go:""GO:0006397""(mRNA processing)|go:""GO:0008289""(lipid binding)|go:""GO:0008380""(RNA splicing)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016607""(nuclear speck)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035061""(interchromatin granule)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0048511""(rhythmic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071765""(nuclear inner membrane organization)|go:""GO:0097157""(pre-mRNA intronic binding)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1990000""(amyloid fibril formation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|interpro:IPR049124|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|rcsb pdb:7N9H|rcsb pdb:7PY2|rcsb pdb:7Q3U|rcsb pdb:8A6I|rcsb pdb:8CG3|rcsb pdb:8CGG|rcsb pdb:8CGH|rcsb pdb:8QX9|rcsb pdb:8QXA|rcsb pdb:8QXB|rcsb pdb:9FOF|rcsb pdb:9FOR|refseq:NP_031401.1|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|efo:""Orphanet:275872""|efo:""Orphanet:803""|dip:DIP-31167N|panther:PTHR48033(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:O60573	intact:EBI-25401182	intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416.3	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"refseq:NP_004837.1|ensembl:ENSG00000135930.15(gene)|ensembl:ENST00000258416.8(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0098808""(mRNA cap binding)|interpro:IPR001040(""Eukaryotic translation initiation factor 4E (eIF-4E)"")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|dip:DIP-32578N|refseq:NP_001263265.1|panther:PTHR11960(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L6J6	uniprotkb:Q99733	intact:EBI-25401182	intact:EBI-2255116|ensembl:ENSP00000369915.4|ensembl:ENSP00000483728.1|uniprotkb:B2R6J4|uniprotkb:F5HFY4	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	psi-mi:np1l4_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)|uniprotkb:NAP2(gene name synonym)|uniprotkb:Nucleosome assembly protein 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401190|imex:IM-27663-5	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	"ensembl:ENSG00000205531.14(gene)|ensembl:ENSG00000273562.4(gene)|ensembl:ENST00000380542.9(transcript)|ensembl:ENST00000619695.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0031491""(nucleosome binding)|go:""GO:0042393""(histone binding)|go:""GO:0051082""(unfolded protein binding)|interpro:IPR002164(""Nucleosome assembly protein (NAP)"")|interpro:IPR037231|mint:Q99733|refseq:NP_005960.1|panther:PTHR11875(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	rogid:tES8IJDlW4JONR/pdC8dq49I/7Y9606	intact-crc:007C3121C5067654|rigid:9x/dhVesyGAvfeAAKoNaNxbAFy0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q16543	uniprotkb:A0A0H3L6W4	intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005.1|intact:EBI-21355356	intact:EBI-25401270	psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym)	psi-mi:a0a0h3l6w4_mycte(display_long)|uniprotkb:lpqR(gene name)|psi-mi:lpqR(display_short)|uniprotkb:ERDMAN_0929(locus name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401282|imex:IM-27663-7	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_008996.1|ensembl:ENSG00000105401.10(gene)|ensembl:ENST00000222005.7(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006605""(protein targeting)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0060334""(regulation of type II interferon-mediated signaling pathway)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1990565""(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|rcsb pdb:7Z37|rcsb pdb:7Z38|rcsb pdb:7ZR0|rcsb pdb:7ZR5|rcsb pdb:7ZR6|rcsb pdb:8GAE|rcsb pdb:8GFT|rcsb pdb:8U1L|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|dip:DIP-27560N|panther:PTHR12800(orthology-group)"	"go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016805""(dipeptidase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR000755(Peptidase M15D, vanX D-ala-D-ala dipeptidase)|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)|mint:A0A0H3L6W4"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/26	rogid:iajhitd2iEmd17KfpU/nMaKc4049606	rogid:wBUoDUaVehtZ7llTDYrEF18jLSY652616	intact-crc:EA33A9AB2451CAF2|rigid:Y+3wG2ThFANd9Kq4J0H1ZtrLst8	false	-	strep tag:c-c	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q8N813	uniprotkb:A0A0H3L4A6	intact:EBI-18115268|uniprotkb:B2RNW5|ensembl:ENSP00000493276.1	intact:EBI-25401304	psi-mi:pr23e_human(display_long)|uniprotkb:PRR23E(gene name)|psi-mi:PRR23E(display_short)|uniprotkb:C3orf56(gene name synonym)	psi-mi:a0a0h3l4a6_mycte(display_long)|uniprotkb:mtc28(gene name)|psi-mi:mtc28(display_short)|uniprotkb:ERDMAN_0048(locus name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401296|imex:IM-27663-45	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	panther:PTHR31813(orthology-group)|refseq:NP_001007535.1|ensembl:ENSG00000214324.5(gene)|ensembl:ENST00000624688.2(transcript)|mint:Q8N813	refseq:WP_003900793.1|interpro:IPR019674|mint:A0A0H3L4A6	-	-	-	figure legend:SF4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:JrqbvIJAi/U+7mqrfj6FEwIGVPI9606	rogid:VEmgJig3VcWCQJBEVzhT5K7IN1A652616	intact-crc:F4FE1F0F6B7E3CD1|rigid:kwNbDZSN40PX2g9CCCZ8HU4vU8w	false	-	strep tag:c-c	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBR3	uniprotkb:O60488	intact:EBI-25401311	intact:EBI-2643816|uniprotkb:O60849|uniprotkb:O60848|uniprotkb:Q5JWV8|uniprotkb:D3DUY2|ensembl:ENSP00000339787.2|ensembl:ENSP00000419171.2|ensembl:ENSP00000425408.2|ensembl:ENSP00000500897.1	psi-mi:a0a0h3lbr3_mycte(display_long)|uniprotkb:PE25(gene name)|psi-mi:PE25(display_short)|uniprotkb:ERDMAN_2675(locus name)	psi-mi:acsl4_human(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 4(gene name synonym)|uniprotkb:ACS4(gene name synonym)|uniprotkb:FACL4(gene name synonym)|uniprotkb:LACS4(gene name synonym)|uniprotkb:ACSL4(gene name)|psi-mi:ACSL4(display_short)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401320|imex:IM-27663-9	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:4W4K|rcsb pdb:4W4L|interpro:IPR000084(PE N-terminal)|refseq:WP_003412551.1|mint:A0A0H3LBR3	"ensembl:ENSG00000068366.21(gene)|ensembl:ENST00000340800.7(transcript)|ensembl:ENST00000469796.7(transcript)|ensembl:ENST00000502391.6(transcript)|ensembl:ENST00000671846.1(transcript)|go:""GO:0001676""(long-chain fatty acid metabolic process)|go:""GO:0004467""(long-chain fatty acid-CoA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0008610""(lipid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0031957""(very long-chain fatty acid-CoA ligase activity)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032307""(negative regulation of prostaglandin secretion)|go:""GO:0035336""(long-chain fatty-acyl-CoA metabolic process)|go:""GO:0035338""(long-chain fatty-acyl-CoA biosynthetic process)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0047676""(arachidonate-CoA ligase activity)|go:""GO:0060136""(embryonic process involved in female pregnancy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090433""(palmitoyl-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR042099|interpro:IPR045851|mint:O60488|reactome:R-HSA-434313|reactome:R-HSA-75876|refseq:NP_001305438.1|refseq:NP_001305439.1|refseq:NP_004449.1|refseq:NP_075266.1|refseq:XP_005262166.1|refseq:XP_006724698.1|refseq:XP_011529190.1|refseq:XP_011529191.1|efo:""Orphanet:777""|efo:""Orphanet:86818""|panther:PTHR43272(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:Cf3zce+v83q+nBny06xFJ3MF0eA652616	rogid:5qETfD5b3GoM+c+cTu1odyXIWgY9606	intact-crc:0AD4C52938B81536|rigid:IGqNlmHNfVxF476dC3jsAI2msLQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBR3	uniprotkb:Q99536	intact:EBI-25401311	intact:EBI-2514883|uniprotkb:Q5BKZ7|uniprotkb:A8K345|uniprotkb:Q13035|uniprotkb:Q9BUT8|uniprotkb:Q96A39|ensembl:ENSP00000347872.2|uniprotkb:B0AZP7|uniprotkb:B4DPX4|intact:EBI-26519135	psi-mi:a0a0h3lbr3_mycte(display_long)|uniprotkb:PE25(gene name)|psi-mi:PE25(display_short)|uniprotkb:ERDMAN_2675(locus name)	psi-mi:vat1_human(display_long)|uniprotkb:VAT1(gene name)|psi-mi:VAT1(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401320|imex:IM-27663-9	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:4W4K|rcsb pdb:4W4L|interpro:IPR000084(PE N-terminal)|refseq:WP_003412551.1|mint:A0A0H3LBR3	"refseq:NP_006364.2|ensembl:ENSG00000108828.16(gene)|ensembl:ENST00000355653.8(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010637""(negative regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002364(Quinone oxidoreductase/zeta-crystallin, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|interpro:IPR052100|mint:Q99536|rcsb pdb:6K9Y|rcsb pdb:6LHR|rcsb pdb:6LII|reactome:R-HSA-6798695|panther:PTHR44054(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:Cf3zce+v83q+nBny06xFJ3MF0eA652616	rogid:CaICWyJ+h3ry4itndQodektQFQo9606	intact-crc:0AD4C52938B81536|rigid:IGqNlmHNfVxF476dC3jsAI2msLQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBR3	uniprotkb:Q9NVJ2	intact:EBI-25401311	intact:EBI-718376|ensembl:ENSP00000256496.3|uniprotkb:B4DI85	psi-mi:a0a0h3lbr3_mycte(display_long)|uniprotkb:PE25(gene name)|psi-mi:PE25(display_short)|uniprotkb:ERDMAN_2675(locus name)	psi-mi:arl8b_human(display_long)|uniprotkb:ADP-ribosylation factor-like protein 10C(gene name synonym)|uniprotkb:Novel small G protein indispensable for equal chromosome segregation 1(gene name synonym)|uniprotkb:ARL8B(gene name)|psi-mi:ARL8B(display_short)|uniprotkb:ARL10C(gene name synonym)|uniprotkb:GIE1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401320|imex:IM-27663-9	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:4W4K|rcsb pdb:4W4L|interpro:IPR000084(PE N-terminal)|refseq:WP_003412551.1|mint:A0A0H3LBR3	"refseq:NP_060654.1|ensembl:ENSG00000134108.14(gene)|ensembl:ENST00000256496.8(transcript)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0002505""(antigen processing and presentation of polysaccharide antigen via MHC class II)|go:""GO:0002747""(antigen processing and presentation following phagocytosis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0007059""(chromosome segregation)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019003""(GDP binding)|go:""GO:0030496""(midbody)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032418""(lysosome localization)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0045202""(synapse)|go:""GO:0046754""(viral exocytosis)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0051233""(spindle midzone)|go:""GO:0051301""(cell division)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090117""(endosome to lysosome transport of low-density lipoprotein particle)|go:""GO:0090385""(phagosome-lysosome fusion)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:1902774""(late endosome to lysosome transport)|go:""GO:1902946""(protein localization to early endosome)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990927""(calcium ion regulated lysosome exocytosis)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044154|mint:Q9NVJ2|rcsb pdb:2AL7|rcsb pdb:8JC5|rcsb pdb:8JCA|panther:PTHR45732(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:Cf3zce+v83q+nBny06xFJ3MF0eA652616	rogid:DLTh63yjvilHei1RUU6P4Ad0TAo9606	intact-crc:0AD4C52938B81536|rigid:IGqNlmHNfVxF476dC3jsAI2msLQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBR3	uniprotkb:Q07812	intact:EBI-25401311	intact:EBI-516580|uniprotkb:P55269|uniprotkb:Q07814|uniprotkb:Q07815|uniprotkb:Q8WZ49|uniprotkb:Q9NR76|uniprotkb:Q9UQD6|uniprotkb:Q9NYG7|uniprotkb:Q9UCZ6|uniprotkb:Q9UCZ7|uniprotkb:A8K4W1|intact:EBI-8995042|ensembl:ENSP00000263262.9	psi-mi:a0a0h3lbr3_mycte(display_long)|uniprotkb:PE25(gene name)|psi-mi:PE25(display_short)|uniprotkb:ERDMAN_2675(locus name)	psi-mi:bax_human(display_long)|uniprotkb:BAX(gene name)|psi-mi:BAX(display_short)|uniprotkb:BCL2L4(gene name synonym)|uniprotkb:Bcl-2-like protein 4(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401320|imex:IM-27663-9	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:4W4K|rcsb pdb:4W4L|interpro:IPR000084(PE N-terminal)|refseq:WP_003412551.1|mint:A0A0H3LBR3	"refseq:NP_004315.1|refseq:NP_620116.1|refseq:NP_620118.1|refseq:NP_620119.2|refseq:XP_016882566.1|refseq:NP_001278357.1|refseq:NP_001278360.1|ensembl:ENSG00000087088.21(gene)|ensembl:ENST00000345358.12(transcript)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0001764""(neuron migration)|go:""GO:0001777""(T cell homeostatic proliferation)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001783""(B cell apoptotic process)|go:""GO:0001822""(kidney development)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002262""(myeloid cell homeostasis)|go:""GO:0002352""(B cell negative selection)|go:""GO:0002358""(B cell homeostatic proliferation)|go:""GO:0002904""(positive regulation of B cell apoptotic process)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005757""(mitochondrial permeability transition pore complex)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006687""(glycosphingolipid metabolic process)|go:""GO:0006808""(regulation of nitrogen utilization)|go:""GO:0006915""(apoptotic process)|go:""GO:0007281""(germ cell development)|go:""GO:0008053""(mitochondrial fusion)|go:""GO:0008289""(lipid binding)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0008637""(apoptotic mitochondrial changes)|go:""GO:0009566""(fertilization)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009651""(response to salt stress)|go:""GO:0010248""(establishment or maintenance of transmembrane electrochemical gradient)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010524""(positive regulation of calcium ion transport into cytosol)|go:""GO:0010917""(negative regulation of mitochondrial membrane potential)|go:""GO:0015267""(channel activity)|go:""GO:0016020""(membrane)|go:""GO:0021854""(hypothalamus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0032471""(negative regulation of endoplasmic reticulum calcium ion concentration)|go:""GO:0032976""(release of matrix enzymes from mitochondria)|go:""GO:0033599""(regulation of mammary gland epithelial cell proliferation)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035234""(ectopic germ cell programmed cell death)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0045136""(development of secondary sexual characteristics)|go:""GO:0046666""(retinal cell programmed cell death)|go:""GO:0046930""(pore complex)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048087""(positive regulation of developmental pigmentation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048515""(spermatid differentiation)|go:""GO:0048597""(post-embryonic camera-type eye morphogenesis)|go:""GO:0048678""(response to axon injury)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0051204""(protein insertion into mitochondrial membrane)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0060011""(Sertoli cell proliferation)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0060057""(apoptotic process involved in mammary gland involution)|go:""GO:0060058""(positive regulation of apoptotic process involved in mammary gland involution)|go:""GO:0060068""(vagina development)|go:""GO:0060402""(calcium ion transport into cytosol)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070242""(thymocyte apoptotic process)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097136""(Bcl-2 family protein complex)|go:""GO:0097144""(BAX complex)|go:""GO:0097145""(BAK complex)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:0098586""(cellular response to virus)|go:""GO:1902110""(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902262""(apoptotic process involved in blood vessel morphogenesis)|go:""GO:1902263""(apoptotic process involved in embryonic digit morphogenesis)|go:""GO:1902445""(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)|go:""GO:1902512""(positive regulation of apoptotic DNA fragmentation)|go:""GO:1903896""(positive regulation of IRE1-mediated unfolded protein response)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|go:""GO:1990117""(B cell receptor apoptotic signaling pathway)|go:""GO:2000243""(positive regulation of reproductive process)|go:""GO:2000673""(positive regulation of motor neuron apoptotic process)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR036834|interpro:IPR046371|mint:Q07812|rcsb pdb:1F16|rcsb pdb:2G5B|rcsb pdb:2K7W|rcsb pdb:2LR1|rcsb pdb:3PK1|rcsb pdb:3PL7|rcsb pdb:4BD2|rcsb pdb:4BD6|rcsb pdb:4BD7|rcsb pdb:4BD8|rcsb pdb:4BDU|rcsb pdb:4S0O|rcsb pdb:4S0P|rcsb pdb:4UF2|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIG|rcsb pdb:4ZIH|rcsb pdb:4ZII|rcsb pdb:5W5X|rcsb pdb:5W5Z|rcsb pdb:5W60|rcsb pdb:5W61|rcsb pdb:6EB6|rcsb pdb:6L8V|rcsb pdb:6L95|rcsb pdb:6TRR|rcsb pdb:6XY6|rcsb pdb:7ADT|rcsb pdb:8G1T|rcsb pdb:8SPE|rcsb pdb:8SPF|rcsb pdb:8SPZ|rcsb pdb:8SRX|rcsb pdb:8SRY|rcsb pdb:8SVK|reactome:R-HSA-111457|reactome:R-HSA-114294|reactome:R-HSA-5620971|reactome:R-HSA-6803204|reactome:R-HSA-6804114|reactome:R-HSA-8878166|reactome:R-HSA-9603505|dip:DIP-232N|panther:PTHR11256(orthology-group)|ensembl:ENST00000293288.12|ensembl:ENSP00000293288.8|ensembl:ENSP00000263262.9|ensembl:ENST00000354470.7|ensembl:ENSP00000346461.3|ensembl:ENST00000356483.8|ensembl:ENSP00000348871.4|ensembl:ENST00000415969.6|ensembl:ENSP00000389971.2|ensembl:ENST00000515540.5|ensembl:ENSP00000426328.1"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:Cf3zce+v83q+nBny06xFJ3MF0eA652616	rogid:+Fz2No3HFxN4vZ+KGhDcgPQhpLo9606	intact-crc:0AD4C52938B81536|rigid:IGqNlmHNfVxF476dC3jsAI2msLQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBR3	uniprotkb:Q15738	intact:EBI-25401311	intact:EBI-4280135|uniprotkb:D3DWT6|uniprotkb:O00344|ensembl:ENSP00000359297.3|ensembl:ENSP00000391854.1|ensembl:ENSP00000517980.1|ensembl:ENSP00000517982.1	psi-mi:a0a0h3lbr3_mycte(display_long)|uniprotkb:PE25(gene name)|psi-mi:PE25(display_short)|uniprotkb:ERDMAN_2675(locus name)	psi-mi:nsdhl_human(display_long)|uniprotkb:NSDHL(gene name)|psi-mi:NSDHL(display_short)|uniprotkb:H105E3(gene name synonym)|uniprotkb:Protein H105e3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401320|imex:IM-27663-9	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:4W4K|rcsb pdb:4W4L|interpro:IPR000084(PE N-terminal)|refseq:WP_003412551.1|mint:A0A0H3LBR3	"ensembl:ENSG00000147383.11(gene)|ensembl:ENSG00000292192.1(gene)|ensembl:ENST00000370274.8(transcript)|ensembl:ENST00000440023.5(transcript)|ensembl:ENST00000709998.1(transcript)|ensembl:ENST00000710000.1(transcript)|go:""GO:0000252""(""3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity"")|go:""GO:0001942""(hair follicle development)|go:""GO:0003854""(""3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity"")|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0102175""(""3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity"")|interpro:IPR002225(3-beta hydroxysteroid dehydrogenase/isomerase)|interpro:IPR036291|interpro:IPR050177|mint:Q15738|rcsb pdb:6JKG|rcsb pdb:6JKH|reactome:R-HSA-191273|refseq:NP_001123237.1|refseq:NP_057006.1|refseq:XP_011529480.1|efo:""Orphanet:139""|efo:""Orphanet:251383""|panther:PTHR10366(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:Cf3zce+v83q+nBny06xFJ3MF0eA652616	rogid:Hfd2Gvro+f9sk/Wn2Dxsgh1nbfo9606	intact-crc:0AD4C52938B81536|rigid:IGqNlmHNfVxF476dC3jsAI2msLQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LH51	uniprotkb:P63167	intact:EBI-25401369	intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577.6|ensembl:ENSP00000376296.2|ensembl:ENSP00000376297.2|ensembl:ENSP00000446614.1|ensembl:ENSP00000447907.1	psi-mi:a0a0h3lh51_mycte(display_long)|uniprotkb:PE35(gene name)|psi-mi:PE35(display_short)|uniprotkb:ERDMAN_4246(locus name)	psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401350|imex:IM-27663-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003399870.1|interpro:IPR000084(PE N-terminal)|mint:A0A0H3LH51	"refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|ensembl:ENSG00000088986.11(gene)|ensembl:ENST00000242577.11(transcript)|ensembl:ENST00000392508.2(transcript)|ensembl:ENST00000392509.6(transcript)|ensembl:ENST00000548342.5(transcript)|ensembl:ENST00000549989.1(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0016020""(membrane)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030286""(dynein complex)|go:""GO:0035721""(intraciliary retrograde transport)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042326""(negative regulation of phosphorylation)|go:""GO:0044458""(motile cilium assembly)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0060703""(deoxyribonuclease inhibitor activity)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0072686""(mitotic spindle)|go:""GO:0097542""(ciliary tip)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0110027""(negative regulation of DNA strand resection involved in replication fork processing)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|rcsb pdb:8PR0|rcsb pdb:8PR1|rcsb pdb:8PTK|rcsb pdb:8RGG|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|dip:DIP-33150N|panther:PTHR11886(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:pCiIMfJP1mSoFMWAhd5x0Fc03uM652616	rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606	intact-crc:3510454975E3CF02|rigid:mJWHgSOnDDaU+3F/tclJjjjKgT4	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LH51	uniprotkb:P49790	intact:EBI-25401369	intact:EBI-286779|uniprotkb:Q5T9I7|intact:EBI-1237421|ensembl:ENSP00000262077.3|uniprotkb:E7EPX5|uniprotkb:Q4LE47|uniprotkb:Q7Z743|uniprotkb:B4DIK2|uniprotkb:F6QR24	psi-mi:a0a0h3lh51_mycte(display_long)|uniprotkb:PE35(gene name)|psi-mi:PE35(display_short)|uniprotkb:ERDMAN_4246(locus name)	psi-mi:nu153_human(display_long)|uniprotkb:Nucleoporin Nup153(gene name synonym)|uniprotkb:153 kDa nucleoporin(gene name synonym)|uniprotkb:NUP153(gene name)|psi-mi:NUP153(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401350|imex:IM-27663-11	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003399870.1|interpro:IPR000084(PE N-terminal)|mint:A0A0H3LH51	"refseq:NP_005115.2|ensembl:ENSG00000124789.12(gene)|ensembl:ENST00000262077.3(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0016020""(membrane)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034399""(nuclear periphery)|go:""GO:0042405""(nuclear inclusion body)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043657""(host cell)|go:""GO:0044615""(nuclear pore nuclear basket)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046832""(negative regulation of RNA export from nucleus)|go:""GO:0046872""(metal ion binding)|go:""GO:0051028""(mRNA transport)|go:""GO:0051292""(nuclear pore complex assembly)|go:""GO:0075732""(viral penetration into host nucleus)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1990000""(amyloid fibril formation)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013913(Nucleoporin, Nup153-like)|interpro:IPR018892|interpro:IPR026054|interpro:IPR036443|mint:P49790|rcsb pdb:2EBQ|rcsb pdb:2EBR|rcsb pdb:2EBV|rcsb pdb:2GQE|rcsb pdb:4U0C|rcsb pdb:4U0D|rcsb pdb:5TSV|rcsb pdb:5TSX|rcsb pdb:6AYA|rcsb pdb:8CKY|rcsb pdb:8CL0|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9705671|refseq:NP_001265138.1|refseq:NP_001265139.1|dip:DIP-38185N|panther:PTHR23193(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:pCiIMfJP1mSoFMWAhd5x0Fc03uM652616	rogid:rOax/ikcAu5fmDiCOauVr7Y/fzY9606	intact-crc:3510454975E3CF02|rigid:mJWHgSOnDDaU+3F/tclJjjjKgT4	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L5M6	uniprotkb:P49755	intact:EBI-25401393	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145.4	psi-mi:a0a0h3l5m6_mycte(display_long)|uniprotkb:PPE11(gene name)|psi-mi:PPE11(display_short)|uniprotkb:ERDMAN_0497(locus name)	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401386|imex:IM-27663-13	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0052572""(response to host immune response)|refseq:WP_003898460.1|interpro:IPR000030(Mycobacterial PPE protein)|interpro:IPR038332|interpro:IPR043641|mint:A0A0H3L5M6"	"refseq:NP_006818.3|ensembl:ENSG00000170348.9(gene)|ensembl:ENST00000303575.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0032732""(positive regulation of interleukin-1 production)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0035964""(COPI-coated vesicle budding)|go:""GO:0042470""(melanosome)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0048199""(vesicle targeting, to, from or within Golgi)|go:""GO:0048205""(COPI coating of Golgi vesicle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0070765""(gamma-secretase complex)|go:""GO:0106272""(protein localization to ERGIC)|go:""GO:0106273""(cytosol to ERGIC protein transport)|go:""GO:1902003""(regulation of amyloid-beta formation)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR22811(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:T/W9IaA7v1OFNox3rxioc9+oHRM652616	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	intact-crc:8286D3B5D9541531|rigid:R1jSs3pKAp2h8wQPVi+PPv5sjTk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L5M6	uniprotkb:Q13724	intact:EBI-25401393	intact:EBI-720141|uniprotkb:Q17RN9|uniprotkb:Q8TCT5|uniprotkb:A8K938|uniprotkb:F5H6D0|ensembl:ENSP00000410992.3	psi-mi:a0a0h3l5m6_mycte(display_long)|uniprotkb:PPE11(gene name)|psi-mi:PPE11(display_short)|uniprotkb:ERDMAN_0497(locus name)	psi-mi:mogs_human(display_long)|uniprotkb:Processing A-glucosidase I(gene name synonym)|uniprotkb:MOGS(gene name)|psi-mi:MOGS(display_short)|uniprotkb:GCS1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401386|imex:IM-27663-13	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0052572""(response to host immune response)|refseq:WP_003898460.1|interpro:IPR000030(Mycobacterial PPE protein)|interpro:IPR038332|interpro:IPR043641|mint:A0A0H3L5M6"	"efo:""Orphanet:79330""|refseq:NP_006293.2|ensembl:ENSG00000115275.15(gene)|ensembl:ENST00000448666.7(transcript)|go:""GO:0004573""(Glc3Man9GlcNAc2 oligosaccharide glucosidase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006457""(protein folding)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0009311""(oligosaccharide metabolic process)|go:""GO:0015926""(glucosidase activity)|go:""GO:0016020""(membrane)|go:""GO:0019082""(viral protein processing)|go:""GO:0070062""(extracellular exosome)|interpro:IPR004888(Glycoside hydrolase, family 63)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR031335|interpro:IPR031631|interpro:IPR038518|mint:Q13724|reactome:R-HSA-4793954|reactome:R-HSA-532668|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:NP_001139630.1|panther:PTHR10412(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:T/W9IaA7v1OFNox3rxioc9+oHRM652616	rogid:odbL3NUcP483ilKg/CMVn2GtdVs9606	intact-crc:8286D3B5D9541531|rigid:R1jSs3pKAp2h8wQPVi+PPv5sjTk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O95398	uniprotkb:A0A0H3L6R4	intact:EBI-6172806|uniprotkb:O95634|uniprotkb:Q8WVN0|uniprotkb:A8K2G5|uniprotkb:E7EQC8|ensembl:ENSP00000373864.3|ensembl:ENSP00000395708.2	intact:EBI-25401486	psi-mi:rpgf3_human(display_long)|uniprotkb:RAPGEF3(gene name)|psi-mi:RAPGEF3(display_short)|uniprotkb:CGEF1(gene name synonym)|uniprotkb:EPAC(gene name synonym)|uniprotkb:EPAC1(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 1(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 1(gene name synonym)|uniprotkb:Rap1 guanine-nucleotide-exchange factor directly activated by cAMP(gene name synonym)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor I(gene name synonym)	psi-mi:a0a0h3l6r4_mycte(display_long)|uniprotkb:ERDMAN_0870(locus name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401490|imex:IM-27663-29	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001092002.1|refseq:NP_006096.2|ensembl:ENSG00000079337.16(gene)|ensembl:ENST00000389212.7(transcript)|ensembl:ENST00000449771.7(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0007165""(signal transduction)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0008306""(associative learning)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030175""(filopodium)|go:""GO:0030552""(cAMP binding)|go:""GO:0032486""(Rap protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034242""(negative regulation of syncytium formation by plasma membrane fusion)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060143""(positive regulation of syncytium formation by plasma membrane fusion)|go:""GO:0061028""(establishment of endothelial barrier)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071320""(cellular response to cAMP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|interpro:IPR036964|mint:O95398|rcsb pdb:6H7E|reactome:R-HSA-354192|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|panther:PTHR23113(orthology-group)"	mint:A0A0H3L6R4	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:JTvCAJZQHQvt9s2Z2GDOszHq0pk9606	rogid:uziJm9KcopWZqQBfOh5DkS6p3bU652616	intact-crc:5EE6ACA900B6E09B|rigid:UyOuGXeNtyAp2wJ7ivfz79uTwZI	false	-	strep tag:c-c	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q9BX66	uniprotkb:A0A0H3LBC5	intact:EBI-433642|ensembl:ENSP00000355136.3|ensembl:ENSP00000360293.2|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932	intact:EBI-25401496	psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym)	psi-mi:a0a0h3lbc5_mycte(display_long)|uniprotkb:ERDMAN_1112(locus name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401502|imex:IM-27663-47	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000095637.23(gene)|ensembl:ENST00000361941.7(transcript)|ensembl:ENST00000371247.7(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016600""(flotillin complex)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0045121""(membrane raft)|go:""GO:0045725""(positive regulation of glycogen biosynthetic process)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0046889""(positive regulation of lipid biosynthetic process)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|interpro:IPR050384|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|panther:PTHR14167(orthology-group)"	interpro:IPR041313|mint:A0A0H3LBC5	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606	rogid:CxxtTIvkvnCKVO1k97ChAr0bxF0652616	intact-crc:387DFFFE1C416545|rigid:15v7nRYPYdEuG3Yb/XgOKGa4QqI	false	-	strep tag:c-c	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBL5	uniprotkb:P63151	intact:EBI-25401508	intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113.3	psi-mi:a0a0h3lbl5_mycte(display_long)|uniprotkb:ERDMAN_1200(locus name)	psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401515|imex:IM-27663-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|interpro:IPR051532|interpro:IPR036514|refseq:WP_003405726.1|interpro:IPR013830(Esterase, SGNH hydrolase-type)|mint:A0A0H3LBL5"	"refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914.11(gene)|ensembl:ENST00000380737.8(transcript)|go:""GO:0000159""(protein phosphatase type 2A complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0043278""(response to morphine)|go:""GO:0051983""(regulation of chromosome segregation)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140767""(enzyme-substrate adaptor activity)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|rcsb pdb:8SO0|rcsb pdb:8TTB|rcsb pdb:8TWE|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|reactome:R-HSA-9860927|dip:DIP-29398N|panther:PTHR11871(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:ov6DqTBjygJMfMPfntt6rUFnwho652616	rogid:evS6klM2alZXtMthVsshKkrNgiA9606	intact-crc:32A041EEB0736D71|rigid:uOmaZjFz2aeO36QwvpBPjKQwfxM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBL5	uniprotkb:Q15291	intact:EBI-25401508	intact:EBI-592823|ensembl:ENSP00000264515.6|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7	psi-mi:a0a0h3lbl5_mycte(display_long)|uniprotkb:ERDMAN_1200(locus name)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401515|imex:IM-27663-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|interpro:IPR051532|interpro:IPR036514|refseq:WP_003405726.1|interpro:IPR013830(Esterase, SGNH hydrolase-type)|mint:A0A0H3LBL5"	"ensembl:ENSG00000117222.14(gene)|ensembl:ENST00000264515.11(transcript)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006974""(DNA damage response)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042393""(histone binding)|go:""GO:0043627""(response to estrogen)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0071339""(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|rcsb pdb:7MBM|rcsb pdb:7MBN|rcsb pdb:7UD5|rcsb pdb:7W67|rcsb pdb:7W6A|rcsb pdb:7W6I|rcsb pdb:7W6J|rcsb pdb:7W6L|rcsb pdb:8DU4|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922|refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|panther:PTHR44040(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:ov6DqTBjygJMfMPfntt6rUFnwho652616	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	intact-crc:32A041EEB0736D71|rigid:uOmaZjFz2aeO36QwvpBPjKQwfxM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBL5	uniprotkb:P62714	intact:EBI-25401508	intact:EBI-1044367|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5|ensembl:ENSP00000221138.4	psi-mi:a0a0h3lbl5_mycte(display_long)|uniprotkb:ERDMAN_1200(locus name)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401515|imex:IM-27663-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|interpro:IPR051532|interpro:IPR036514|refseq:WP_003405726.1|interpro:IPR013830(Esterase, SGNH hydrolase-type)|mint:A0A0H3LBL5"	"refseq:NP_001009552.1|dip:DIP-42325N|ensembl:ENSG00000104695.13(gene)|ensembl:ENST00000221138.9(transcript)|go:""GO:0000159""(protein phosphatase type 2A complex)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000922""(spindle pole)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008637""(apoptotic mitochondrial changes)|go:""GO:0010288""(response to lead ion)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035970""(peptidyl-threonine dephosphorylation)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0046580""(negative regulation of Ras protein signal transduction)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046872""(metal ion binding)|go:""GO:0048156""(tau protein binding)|go:""GO:0070262""(peptidyl-serine dephosphorylation)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1904528""(positive regulation of microtubule binding)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186(""Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase"")|interpro:IPR029052|interpro:IPR047129|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-9833482|panther:PTHR45619(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:ov6DqTBjygJMfMPfntt6rUFnwho652616	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	intact-crc:32A041EEB0736D71|rigid:uOmaZjFz2aeO36QwvpBPjKQwfxM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBL5	uniprotkb:P30153	intact:EBI-25401508	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804.6	psi-mi:a0a0h3lbl5_mycte(display_long)|uniprotkb:ERDMAN_1200(locus name)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401515|imex:IM-27663-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|interpro:IPR051532|interpro:IPR036514|refseq:WP_003405726.1|interpro:IPR013830(Esterase, SGNH hydrolase-type)|mint:A0A0H3LBL5"	"ensembl:ENSG00000105568.19(gene)|ensembl:ENST00000322088.11(transcript)|go:""GO:0000159""(protein phosphatase type 2A complex)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007143""(female meiotic nuclear division)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0030425""(dendrite)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0040008""(regulation of growth)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0045595""(regulation of cell differentiation)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051232""(meiotic spindle elongation)|go:""GO:0051306""(mitotic sister chromatid separation)|go:""GO:0051754""(meiotic sister chromatid cohesion, centromeric)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1903538""(regulation of meiotic cell cycle process involved in oocyte maturation)|go:""GO:1990405""(protein antigen binding)|go:""GO:2001241""(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR051023|interpro:IPR054573|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|rcsb pdb:7PKS|rcsb pdb:7SOY|rcsb pdb:7YCX|rcsb pdb:8RBX|rcsb pdb:8RBZ|rcsb pdb:8RC4|rcsb pdb:8SO0|rcsb pdb:8TTB|rcsb pdb:8TWE|rcsb pdb:8TWI|rcsb pdb:8U1X|rcsb pdb:8U89|rcsb pdb:8UWB|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|reactome:R-HSA-9833482|reactome:R-HSA-9860927|refseq:NP_055040.2|efo:""Orphanet:457284""|dip:DIP-29394N|ensembl:ENSP00000324804.6|panther:PTHR10648(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:ov6DqTBjygJMfMPfntt6rUFnwho652616	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:32A041EEB0736D71|rigid:uOmaZjFz2aeO36QwvpBPjKQwfxM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBL5	uniprotkb:O00743	intact:EBI-25401508	intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648.4	psi-mi:a0a0h3lbl5_mycte(display_long)|uniprotkb:ERDMAN_1200(locus name)	psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401515|imex:IM-27663-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|interpro:IPR051532|interpro:IPR036514|refseq:WP_003405726.1|interpro:IPR013830(Esterase, SGNH hydrolase-type)|mint:A0A0H3LBL5"	"refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|ensembl:ENSG00000119414.12(gene)|ensembl:ENST00000373547.9(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0045087""(innate immune response)|go:""GO:0046872""(metal ion binding)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0160049""(negative regulation of cGAS/STING signaling pathway)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186(""Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase"")|interpro:IPR029052|interpro:IPR047129|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005|dip:DIP-27581N|panther:PTHR45619(orthology-group)|ensembl:ENSP00000362648.4|ensembl:ENST00000415905.5|ensembl:ENSP00000411744.1|ensembl:ENST00000451402.5|ensembl:ENSP00000392147.1"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:ov6DqTBjygJMfMPfntt6rUFnwho652616	rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606	intact-crc:32A041EEB0736D71|rigid:uOmaZjFz2aeO36QwvpBPjKQwfxM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBL5	uniprotkb:Q9UBL3	intact:EBI-25401508	intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|uniprotkb:A8K7C3|uniprotkb:D3DSW9|ensembl:ENSP00000340896.5	psi-mi:a0a0h3lbl5_mycte(display_long)|uniprotkb:ERDMAN_1200(locus name)	psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401515|imex:IM-27663-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|interpro:IPR051532|interpro:IPR036514|refseq:WP_003405726.1|interpro:IPR013830(Esterase, SGNH hydrolase-type)|mint:A0A0H3LBL5"	"refseq:NP_001098684.1|refseq:NP_004665.2|refseq:NP_001248761.1|ensembl:ENSG00000129691.16(gene)|ensembl:ENST00000343823.11(transcript)|go:""GO:0000791""(euchromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006974""(DNA damage response)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0030097""(hemopoiesis)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0043627""(response to estrogen)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0071339""(MLL1 complex)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|interpro:IPR043136|interpro:IPR049455|interpro:IPR053835|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|rcsb pdb:7MBM|rcsb pdb:7MBN|rcsb pdb:7UD5|rcsb pdb:7W67|rcsb pdb:7W6A|rcsb pdb:7W6I|rcsb pdb:7W6J|rcsb pdb:7W6L|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922|dip:DIP-29222N|panther:PTHR10598(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:ov6DqTBjygJMfMPfntt6rUFnwho652616	rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606	intact-crc:32A041EEB0736D71|rigid:uOmaZjFz2aeO36QwvpBPjKQwfxM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBL5	uniprotkb:P09622	intact:EBI-25401508	intact:EBI-353366|ensembl:ENSP00000205402.3|ensembl:ENSP00000390667.1|uniprotkb:Q14131|uniprotkb:Q14167|uniprotkb:Q59EV8|uniprotkb:Q8WTS4|uniprotkb:B2R5X0|uniprotkb:B4DHG0|uniprotkb:B4DT69	psi-mi:a0a0h3lbl5_mycte(display_long)|uniprotkb:ERDMAN_1200(locus name)	psi-mi:dldh_human(display_long)|uniprotkb:DLD(gene name)|psi-mi:DLD(display_short)|uniprotkb:GCSL(gene name synonym)|uniprotkb:LAD(gene name synonym)|uniprotkb:PHE3(gene name synonym)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Glycine cleavage system L protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401515|imex:IM-27663-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|interpro:IPR051532|interpro:IPR036514|refseq:WP_003405726.1|interpro:IPR013830(Esterase, SGNH hydrolase-type)|mint:A0A0H3LBL5"	"ensembl:ENSG00000091140.15(gene)|ensembl:ENST00000205402.10(transcript)|ensembl:ENST00000417551.5(transcript)|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006086""(pyruvate decarboxylation to acetyl-CoA)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0006120""(mitochondrial electron transport, NADH to ubiquinone)|go:""GO:0006508""(proteolysis)|go:""GO:0007369""(gastrulation)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0031514""(motile cilium)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0043159""(acrosomal matrix)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|go:""GO:0045254""(pyruvate dehydrogenase complex)|go:""GO:0048240""(sperm capacitation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0160157""(branched-chain alpha-ketoacid dehydrogenase complex)|go:""GO:0160167""(oxoadipate dehydrogenase complex)|go:""GO:1902493""(acetyltransferase complex)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|interpro:IPR050151|mint:P09622|rcsb pdb:1ZMC|rcsb pdb:1ZMD|rcsb pdb:1ZY8|rcsb pdb:2F5Z|rcsb pdb:3RNM|rcsb pdb:5J5Z|rcsb pdb:5NHG|rcsb pdb:6HG8|rcsb pdb:6I4P|rcsb pdb:6I4Q|rcsb pdb:6I4R|rcsb pdb:6I4S|rcsb pdb:6I4T|rcsb pdb:6I4U|rcsb pdb:6I4Z|rcsb pdb:7PSC|rcsb pdb:7ZYT|reactome:R-HSA-204174|reactome:R-HSA-5362517|reactome:R-HSA-6783984|reactome:R-HSA-70895|reactome:R-HSA-9837999|reactome:R-HSA-9853506|reactome:R-HSA-9858328|reactome:R-HSA-9859138|reactome:R-HSA-9861559|reactome:R-HSA-9865113|reactome:R-HSA-9907570|reactome:R-HSA-9912481|reactome:R-HSA-9912529|refseq:NP_000099.2|refseq:NP_001276679.1|refseq:NP_001276680.1|refseq:NP_001276681.1|efo:""Orphanet:2394""|dip:DIP-29027N|panther:PTHR22912(orthology-group)"	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:7613492C516F3835	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:ov6DqTBjygJMfMPfntt6rUFnwho652616	rogid:7Yf9KyBWf18686aOXVUwab65rl89606	intact-crc:32A041EEB0736D71|rigid:uOmaZjFz2aeO36QwvpBPjKQwfxM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBL5	uniprotkb:P35268	intact:EBI-25401508	intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088.3	psi-mi:a0a0h3lbl5_mycte(display_long)|uniprotkb:ERDMAN_1200(locus name)	psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:60S ribosomal protein L22(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401515|imex:IM-27663-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|interpro:IPR051532|interpro:IPR036514|refseq:WP_003405726.1|interpro:IPR013830(Esterase, SGNH hydrolase-type)|mint:A0A0H3LBL5"	"refseq:NP_000974.1|ensembl:ENSG00000116251.11(gene)|ensembl:ENST00000234875.9(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0008201""(heparin binding)|go:""GO:0022625""(cytosolic large ribosomal subunit)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0046632""(alpha-beta T cell differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140236""(translation at presynapse)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:7F5S|rcsb pdb:7QVP|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8A3D|rcsb pdb:8FKZ|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8IR1|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FL9|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLC|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8FLF|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IDT|rcsb pdb:8IDY|rcsb pdb:8IE3|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8INK|rcsb pdb:8IPD|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR3|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8OJ8|rcsb pdb:8QFD|rcsb pdb:8QOI|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9FQ0|rcsb pdb:9G8M|rcsb pdb:9GMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|panther:PTHR10064(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:ov6DqTBjygJMfMPfntt6rUFnwho652616	rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606	intact-crc:32A041EEB0736D71|rigid:uOmaZjFz2aeO36QwvpBPjKQwfxM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBL5	uniprotkb:P61978	intact:EBI-25401508	intact:EBI-304185|intact:EBI-28971491|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|ensembl:ENSP00000317788.4|ensembl:ENSP00000353552.5|ensembl:ENSP00000515619.1|ensembl:ENSP00000515654.1|ensembl:ENSP00000515655.1|ensembl:ENSP00000515656.1|ensembl:ENSP00000515661.1|intact:EBI-3440248|uniprotkb:Q6IBN1	psi-mi:a0a0h3lbl5_mycte(display_long)|uniprotkb:ERDMAN_1200(locus name)	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401515|imex:IM-27663-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|interpro:IPR051532|interpro:IPR036514|refseq:WP_003405726.1|interpro:IPR013830(Esterase, SGNH hydrolase-type)|mint:A0A0H3LBL5"	"efo:""Orphanet:352665""|efo:""Orphanet:453504""|ensembl:ENSG00000165119.22(gene)|ensembl:ENST00000351839.7(transcript)|ensembl:ENST00000360384.9(transcript)|ensembl:ENST00000704006.1(transcript)|ensembl:ENST00000704051.1(transcript)|ensembl:ENST00000704052.1(transcript)|ensembl:ENST00000704053.1(transcript)|ensembl:ENST00000704058.1(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000785""(chromatin)|go:""GO:0002102""(podosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006396""(RNA processing)|go:""GO:0007165""(signal transduction)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010988""(regulation of low-density lipoprotein particle clearance)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042995""(cell projection)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045296""(cadherin binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0048025""(negative regulation of mRNA splicing, via spliceosome)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1902165""(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:1905599""(positive regulation of low-density lipoprotein receptor activity)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|rcsb pdb:1ZZK|rcsb pdb:7CRE|rcsb pdb:7CRU|rcsb pdb:7RJK|rcsb pdb:7RJO|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|refseq:XP_016870157.1|dip:DIP-31805N|panther:PTHR10288(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:ov6DqTBjygJMfMPfntt6rUFnwho652616	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	intact-crc:32A041EEB0736D71|rigid:uOmaZjFz2aeO36QwvpBPjKQwfxM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBL5	uniprotkb:Q9C005	intact:EBI-25401508	intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066.3|ensembl:ENSP00000345837.5	psi-mi:a0a0h3lbl5_mycte(display_long)|uniprotkb:ERDMAN_1200(locus name)	psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401515|imex:IM-27663-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|interpro:IPR051532|interpro:IPR036514|refseq:WP_003405726.1|interpro:IPR013830(Esterase, SGNH hydrolase-type)|mint:A0A0H3LBL5"	"refseq:NP_115963.1|refseq:NP_001308138.1|dip:DIP-34476N|ensembl:ENSG00000162961.14(gene)|ensembl:ENST00000295066.3(transcript)|ensembl:ENST00000342166.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0016197""(endosomal transport)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0071339""(MLL1 complex)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|interpro:IPR049629|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|rcsb pdb:7UD5|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/28	rogid:ov6DqTBjygJMfMPfntt6rUFnwho652616	rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606	intact-crc:32A041EEB0736D71|rigid:uOmaZjFz2aeO36QwvpBPjKQwfxM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P09651	uniprotkb:A0A0H3L929	intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|uniprotkb:A8K4Z8|intact:EBI-2556572|ensembl:ENSP00000503610.1|ensembl:ENSP00000341826.7|intact:EBI-21353669	intact:EBI-25401584	psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)	psi-mi:a0a0h3l929_mycte(display_long)|uniprotkb:ERDMAN_1669(locus name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401592|imex:IM-27663-31	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:1L3K|ensembl:ENSG00000135486.19(gene)|ensembl:ENST00000340913.11(transcript)|ensembl:ENST00000677210.1(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0035198""(miRNA binding)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0051028""(mRNA transport)|go:""GO:0051168""(nuclear export)|go:""GO:0051170""(import into nucleus)|go:""GO:0061752""(telomeric repeat-containing RNA binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0098505""(G-rich strand telomeric DNA binding)|go:""GO:1903936""(cellular response to sodium arsenite)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034516|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|rcsb pdb:7ZJ2|rcsb pdb:8IK7|rcsb pdb:8IKB|rcsb pdb:8IKP|rcsb pdb:8IKS|rcsb pdb:8RZV|rcsb pdb:9F1S|rcsb pdb:9F4D|rcsb pdb:9F4E|rcsb pdb:9F4F|rcsb pdb:9F4G|rcsb pdb:9F4H|rcsb pdb:9F4J|rcsb pdb:9F4K|rcsb pdb:9F4L|rcsb pdb:9F4M|rcsb pdb:9F4N|rcsb pdb:9F4O|rcsb pdb:9F4P|rcsb pdb:9F4Q|rcsb pdb:9F4R|rcsb pdb:9F4S|rcsb pdb:9F4T|rcsb pdb:9F4U|rcsb pdb:9F4V|rcsb pdb:9F4W|rcsb pdb:9F4X|rcsb pdb:9F4Y|rcsb pdb:9F4Z|rcsb pdb:9F50|rcsb pdb:9F51|rcsb pdb:9F52|rcsb pdb:9F53|rcsb pdb:9F54|rcsb pdb:9F55|rcsb pdb:9F5C|rcsb pdb:9F5D|rcsb pdb:9F5E|rcsb pdb:9F5F|rcsb pdb:9F5G|rcsb pdb:9F5K|rcsb pdb:9F7F|rcsb pdb:9F7H|rcsb pdb:9GEA|rcsb pdb:9GPJ|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9692914|reactome:R-HSA-9735869|refseq:NP_002127.1|refseq:NP_112420.1|refseq:XP_005268883.1|efo:""Orphanet:52430""|efo:""Orphanet:803""|dip:DIP-29338N|panther:PTHR48026(orthology-group)"	interpro:IPR050049|refseq:WP_003898900.1|interpro:IPR009923(Dodecin flavoprotein)|interpro:IPR025543|interpro:IPR036694|mint:A0A0H3L929	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606	rogid:rbhRDsT9L/trSxfxe9jh3Qqcv7c652616	intact-crc:8611C1EC4A36F8D9|rigid:Pui8O+JBAW9AD+GUVq2S2wIg8rI	false	-	strep tag:c-c	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:Q9Y3A3	intact:EBI-25401610	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|uniprotkb:B4DML0|ensembl:ENSP00000315702.4	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1|ensembl:ENSG00000115540.15(gene)|ensembl:ENST00000323303.9(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|panther:PTHR22599(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:P23258	intact:EBI-25401610	intact:EBI-302589|uniprotkb:Q9BW59|uniprotkb:Q53X79|ensembl:ENSP00000251413.2	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:tbg1_human(display_long)|uniprotkb:TUBG1(gene name)|psi-mi:TUBG1(display_short)|uniprotkb:TUBG(gene name synonym)|uniprotkb:Gamma-1-tubulin(gene name synonym)|uniprotkb:Gamma-tubulin complex component 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"efo:""Orphanet:261183""|ensembl:ENSG00000131462.9(gene)|ensembl:ENST00000251413.8(transcript)|go:""GO:0000070""(mitotic sister chromatid segregation)|go:""GO:0000212""(meiotic spindle organization)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000242""(pericentriolar material)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000930""(gamma-tubulin complex)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005819""(spindle)|go:""GO:0005827""(polar microtubule)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0045177""(apical part of cell)|go:""GO:0055037""(recycling endosome)|go:""GO:0097730""(non-motile cilium)|go:""GO:1990498""(mitotic spindle microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P23258|rcsb pdb:1Z5V|rcsb pdb:1Z5W|rcsb pdb:3CB2|rcsb pdb:6V5V|rcsb pdb:6V6S|rcsb pdb:7AS4|rcsb pdb:7QJ0|rcsb pdb:7QJ1|rcsb pdb:7QJ2|rcsb pdb:7QJ3|rcsb pdb:7QJ4|rcsb pdb:7QJ5|rcsb pdb:7QJ6|rcsb pdb:7QJ7|rcsb pdb:7QJ8|rcsb pdb:7QJ9|rcsb pdb:7QJA|rcsb pdb:7QJB|rcsb pdb:7QJC|rcsb pdb:7QJD|rcsb pdb:7QJE|rcsb pdb:8Q62|rcsb pdb:8RX1|rcsb pdb:8VA2|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001061.2|dip:DIP-29890N|panther:PTHR11588(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:Y5WLH1ZKlS7FOa9ePmH3dpdE8Xk9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:Q9Y315	intact:EBI-25401610	intact:EBI-1048152|uniprotkb:Q53HN9|uniprotkb:Q6PHW2|ensembl:ENSP00000416583.2	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:deoc_human(display_long)|uniprotkb:2-deoxy-D-ribose 5-phosphate aldolase(gene name synonym)|uniprotkb:Phosphodeoxyriboaldolase(gene name synonym)|uniprotkb:DERA(gene name)|psi-mi:DERA(display_short)|uniprotkb:CGI-26(orf name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_057038.2|ensembl:ENSG00000023697.13(gene)|ensembl:ENST00000428559.7(transcript)|go:""GO:0004139""(deoxyribose-phosphate aldolase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0009264""(deoxyribonucleotide catabolic process)|go:""GO:0016052""(carbohydrate catabolic process)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0046121""(deoxyribonucleoside catabolic process)|go:""GO:0046386""(deoxyribose phosphate catabolic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR002915(Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase)|interpro:IPR011343(Deoxyribose-phosphate aldolase)|interpro:IPR013785(Aldolase-type TIM barrel)|mint:Q9Y315|reactome:R-HSA-6798695|reactome:R-HSA-71336|panther:PTHR10889(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:2gmO8stx2PunDk1T8+r3YqwLBSY9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:Q8IZ83	intact:EBI-25401610	intact:EBI-1044483|uniprotkb:C9JBH6|uniprotkb:Q86YF0|uniprotkb:Q8IYL4|uniprotkb:Q8TEI8|uniprotkb:B4DLQ1|ensembl:ENSP00000293350.3	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:a16a1_human(display_long)|uniprotkb:ALDH16A1(gene name)|psi-mi:ALDH16A1(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_699160.2|refseq:NP_001138868.1|ensembl:ENSG00000161618.10(gene)|ensembl:ENST00000293350.9(transcript)|go:""GO:0016020""(membrane)|go:""GO:0016620""(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q8IZ83|panther:PTHR11699(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:BoCNAGkgDh2oJaclyaoXr117+iw9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:Q96CW5	intact:EBI-25401610	intact:EBI-1046278|uniprotkb:O43631|uniprotkb:O60852|uniprotkb:O60853|uniprotkb:Q7Z4K1|uniprotkb:Q96I79|uniprotkb:Q5T8L2|ensembl:ENSP00000261965.3	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:gcp3_human(display_long)|uniprotkb:Spindle pole body protein Spc98 homolog(gene name synonym)|uniprotkb:TUBGCP3(gene name)|psi-mi:TUBGCP3(display_short)|uniprotkb:GCP3(gene name synonym)|uniprotkb:Gamma-ring complex protein 104 kDa(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_006313.1|refseq:NP_001273207.1|refseq:NP_001273208.1|refseq:NP_001273206.1|ensembl:ENSG00000126216.15(gene)|ensembl:ENST00000261965.8(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000930""(gamma-tubulin complex)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005819""(spindle)|go:""GO:0005827""(polar microtubule)|go:""GO:0005829""(cytosol)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007338""(single fertilization)|go:""GO:0016020""(membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051321""(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q96CW5|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0U|rcsb pdb:7AS4|rcsb pdb:7QJ0|rcsb pdb:7QJ1|rcsb pdb:7QJ2|rcsb pdb:7QJ3|rcsb pdb:7QJ4|rcsb pdb:7QJ5|rcsb pdb:7QJ6|rcsb pdb:7QJ7|rcsb pdb:7QJ8|rcsb pdb:7QJ9|rcsb pdb:7QJA|rcsb pdb:7QJB|rcsb pdb:7QJC|rcsb pdb:7QJD|rcsb pdb:8Q62|rcsb pdb:8RX1|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|reactome:R-HSA-380270|reactome:R-HSA-380320|panther:PTHR19302(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:xt+Ngo2s/4djh2PnyMEaxgDyLrs9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:Q13033	intact:EBI-25401610	intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071.5	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_001077362.1|refseq:NP_055389.3|ensembl:ENSG00000196792.12(gene)|ensembl:ENST00000357479.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0030425""(dendrite)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033147""(negative regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|go:""GO:0098794""(postsynapse)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR051488|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|rcsb pdb:7K36|panther:PTHR15653(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:Q9BSJ2	intact:EBI-25401610	intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936.3|ensembl:ENSP00000506731.1|ensembl:ENSP00000507482.1|ensembl:ENSP00000507610.1|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"ensembl:ENSG00000130640.15(gene)|ensembl:ENST00000252936.8(transcript)|ensembl:ENST00000682123.1(transcript)|ensembl:ENST00000682515.1(transcript)|ensembl:ENST00000683612.1(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000922""(spindle pole)|go:""GO:0000930""(gamma-tubulin complex)|go:""GO:0001764""(neuron migration)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007420""(brain development)|go:""GO:0016020""(membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|rcsb pdb:7QJ0|rcsb pdb:7QJ1|rcsb pdb:7QJ2|rcsb pdb:7QJ3|rcsb pdb:7QJ4|rcsb pdb:7QJ5|rcsb pdb:7QJ6|rcsb pdb:7QJ7|rcsb pdb:7QJ8|rcsb pdb:7QJ9|rcsb pdb:7QJA|rcsb pdb:7QJB|rcsb pdb:7QJC|rcsb pdb:7QJD|rcsb pdb:8Q62|rcsb pdb:8RX1|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|reactome:R-HSA-380270|reactome:R-HSA-380320|refseq:NP_006650.1|refseq:NP_001243547.1|refseq:NP_001243546.1|panther:PTHR19302(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:Q92844	intact:EBI-25401610	intact:EBI-356349|uniprotkb:Q92885|uniprotkb:D3DPB5|uniprotkb:Q7Z4J6|ensembl:ENSP00000259075.2|ensembl:ENSP00000376505.2	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:tank_human(display_long)|uniprotkb:TANK(gene name)|psi-mi:TANK(display_short)|uniprotkb:ITRAF(gene name synonym)|uniprotkb:TRAF2(gene name synonym)|uniprotkb:TRAF-interacting protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_001186064.1|refseq:NP_004171.2|refseq:NP_597841.1|ensembl:ENSG00000136560.14(gene)|ensembl:ENST00000259075.6(transcript)|ensembl:ENST00000392749.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:1902554""(serine/threonine protein kinase complex)|go:""GO:1903003""(positive regulation of protein deubiquitination)|go:""GO:2000158""(positive regulation of ubiquitin-specific protease activity)|interpro:IPR024581|interpro:IPR039669|interpro:IPR041641|mint:Q92844|rcsb pdb:1KZZ|rcsb pdb:1L0A|rcsb pdb:5H10|reactome:R-HSA-9013973|reactome:R-HSA-933541|reactome:R-HSA-936964|reactome:R-HSA-9824878|reactome:R-HSA-9828211|refseq:XP_016858585.1|refseq:XP_016858586.1|dip:DIP-27516N|panther:PTHR15249(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:B6PUVX1PZ5XmFszyF0tRSwfbb4M9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:Q15027	intact:EBI-25401610	intact:EBI-751746|uniprotkb:Q53XN9|ensembl:ENSP00000158762.3|ensembl:ENSP00000499859.1	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:acap1_human(display_long)|uniprotkb:ACAP1(gene name)|psi-mi:ACAP1(display_short)|uniprotkb:Centaurin-beta-1(gene name synonym)|uniprotkb:CENTB1(gene name synonym)|uniprotkb:KIAA0050(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_055531.1|ensembl:ENSG00000072818.12(gene)|ensembl:ENSG00000288169.1(gene)|ensembl:ENST00000158762.8(transcript)|ensembl:ENST00000672212.1(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0055038""(recycling endosome membrane)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR004148(BAR)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|interpro:IPR045258|mint:Q15027|rcsb pdb:3JUE|rcsb pdb:3T9K|rcsb pdb:4CKG|rcsb pdb:4CKH|rcsb pdb:4F1P|rcsb pdb:4NSW|rcsb pdb:5H3D|panther:PTHR23180(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:pdHptA2uWwLfGAtHieVj+hm1udw9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:Q6NZ67	intact:EBI-25401610	intact:EBI-1052566|uniprotkb:Q96CG4|intact:EBI-2555069|ensembl:ENSP00000281871.7|ensembl:ENSP00000517875.1	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:mzt2b_human(display_long)|uniprotkb:MZT2B(gene name)|psi-mi:MZT2B(display_short)|uniprotkb:FAM128B(gene name synonym)|uniprotkb:MOZART2B(gene name synonym)|uniprotkb:Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2B(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_079305.2|ensembl:ENSG00000152082.15(gene)|ensembl:ENSG00000292119.1(gene)|ensembl:ENST00000281871.11(transcript)|ensembl:ENST00000709784.1(transcript)|go:""GO:0000931""(gamma-tubulin ring complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|interpro:IPR024332|mint:Q6NZ67|reactome:R-HSA-380270|reactome:R-HSA-380320|panther:PTHR28578(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:zjtQDl3ebeUtbVBixZvPf25VcxQ9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:O43294	intact:EBI-25401610	intact:EBI-1051449|uniprotkb:Q9BPW3|uniprotkb:Q9Y2V5|uniprotkb:B2R8D5|ensembl:ENSP00000378332.3	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:tgfi1_human(display_long)|uniprotkb:TGFB1I1(gene name)|psi-mi:TGFB1I1(display_short)|uniprotkb:ARA55(gene name synonym)|uniprotkb:Hydrogen peroxide-inducible clone 5 protein(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 55 kDa(gene name synonym)|uniprotkb:Androgen receptor coactivator 55 kDa protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_001035919.1|refseq:NP_001158191.1|refseq:NP_057011.2|dip:DIP-5931N|ensembl:ENSG00000140682.19(gene)|ensembl:ENST00000394863.8(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0016363""(nuclear matrix)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045165""(cell fate commitment)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048495""(Roundabout binding)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0070411""(I-SMAD binding)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|interpro:IPR047075|mint:O43294|panther:PTHR24216(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:ekkGbwdFenBhBn0HzJjd4Szi61U9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:O43815	intact:EBI-25401610	intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918.4|uniprotkb:Q53TQ8|uniprotkb:Q9NP38	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_003153.2|ensembl:ENSG00000115808.13(gene)|ensembl:ENST00000263918.9(transcript)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016358""(dendrite development)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030425""(dendrite)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR051488|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|reactome:R-HSA-9700645|reactome:R-HSA-9725370|panther:PTHR15653(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAM7	uniprotkb:Q9NRL3	intact:EBI-25401610	intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280.4	psi-mi:a0a0h3lam7_mycte(display_long)|uniprotkb:ERDMAN_1994(locus name)	psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401616|imex:IM-27663-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003409065.1|interpro:IPR007969(Protein of unknown function DUF732)|mint:A0A0H3LAM7	"refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372.15(gene)|ensembl:ENST00000263280.11(transcript)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0030425""(dendrite)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR051488|mint:Q9NRL3|panther:PTHR15653(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/01	rogid:MBvvxyl7hm/oZag7d2diWPJHNBE652616	rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606	intact-crc:860665CD7E11AA92|rigid:juFlYDSS2u90M3+NniHJlD2I8DA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L9I7	uniprotkb:Q9NVX7	intact:EBI-25401663	intact:EBI-725970|uniprotkb:Q6IA85|uniprotkb:Q9BUC3|uniprotkb:Q9NV76|uniprotkb:D3DQS2|uniprotkb:D3DQS1|uniprotkb:A0A075B6T4|uniprotkb:B3KRH9|ensembl:ENSP00000415106.2|ensembl:ENSP00000495892.1	psi-mi:a0a0h3l9i7_mycte(display_long)|uniprotkb:ERDMAN_2006(locus name)	psi-mi:kbtb4_human(display_long)|uniprotkb:BTB and kelch domain-containing protein 4(gene name synonym)|uniprotkb:KBTBD4(gene name)|psi-mi:KBTBD4(display_short)|uniprotkb:BKLHD4(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401928|imex:IM-27663-68	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR050109|interpro:IPR009057(Homeodomain-like)|interpro:IPR001647(Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal)|interpro:IPR036271|interpro:IPR025996|refseq:WP_003899034.1|mint:A0A0H3L9I7"	refseq:NP_057590.3|refseq:NP_060565.4|refseq:NP_001305645.1|refseq:NP_001305646.1|refseq:NP_001305647.1|refseq:NP_001305648.1|refseq:NP_001305649.1|refseq:NP_001305650.1|refseq:NP_001305651.1|refseq:NP_001305652.1|refseq:NP_001305653.1|refseq:NP_001305654.1|ensembl:ENSG00000123444.14(gene)|ensembl:ENSG00000284900.2(gene)|ensembl:ENST00000430070.7(transcript)|ensembl:ENST00000647201.2(transcript)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR042884|interpro:IPR042949|interpro:IPR042950|mint:Q9NVX7|rcsb pdb:2EQX|panther:PTHR47195(orthology-group)	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:+nfmZkrPEFtnvh6c6DD2Y0Ox+iE652616	rogid:fyiVZnI2XQGd6PfRfq+Z+4LiWb09606	intact-crc:2C3F5472B78A2BBE|rigid:wX5m871vQ5NFRnFnIEGG0jkuDDc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L9I7	uniprotkb:Q93008	intact:EBI-25401663	intact:EBI-302524|intact:EBI-1058656|intact:EBI-28978998|uniprotkb:O75550|uniprotkb:Q8WWT3|uniprotkb:Q8WX12|ensembl:ENSP00000367558.2|ensembl:ENSP00000515975.1	psi-mi:a0a0h3l9i7_mycte(display_long)|uniprotkb:ERDMAN_2006(locus name)	psi-mi:usp9x_human(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401928|imex:IM-27663-68	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR050109|interpro:IPR009057(Homeodomain-like)|interpro:IPR001647(Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal)|interpro:IPR036271|interpro:IPR025996|refseq:WP_003899034.1|mint:A0A0H3L9I7"	"efo:""Orphanet:480880""|efo:""Orphanet:777""|ensembl:ENSG00000124486.15(gene)|ensembl:ENST00000378308.7(transcript)|ensembl:ENST00000704650.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001764""(neuron migration)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006307""(DNA alkylation repair)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007292""(female gamete generation)|go:""GO:0008104""(protein localization)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016562""(protein import into peroxisome matrix, receptor recycling)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0030426""(growth cone)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0035520""(monoubiquitinated protein deubiquitination)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0048511""(rhythmic process)|go:""GO:0048675""(axon extension)|go:""GO:0050821""(protein stabilization)|go:""GO:0051301""(cell division)|go:""GO:0060271""(cilium assembly)|go:""GO:0061578""(K63-linked deubiquitinase activity)|go:""GO:0061824""(cytosolic ciliogenesis)|go:""GO:0070410""(co-SMAD binding)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0071947""(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:""GO:0101005""(deubiquitinase activity)|go:""GO:0140313""(molecular sequestering activity)|go:""GO:0180017""(K11-linked deubiquitinase activity)|go:""GO:1904515""(positive regulation of TORC2 signaling)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990380""(K48-linked deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR038765|interpro:IPR050164|interpro:IPR055176|mint:Q93008|rcsb pdb:5VBD|rcsb pdb:5WCH|rcsb pdb:7YXX|rcsb pdb:7YXY|reactome:R-HSA-2173795|reactome:R-HSA-5689880|reactome:R-HSA-8866652|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9033241|reactome:R-HSA-977225|refseq:NP_001034679.2|refseq:NP_001034680.2|dip:DIP-27562N|panther:PTHR24006(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:+nfmZkrPEFtnvh6c6DD2Y0Ox+iE652616	rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606	intact-crc:2C3F5472B78A2BBE|rigid:wX5m871vQ5NFRnFnIEGG0jkuDDc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L9I7	uniprotkb:Q86VM9	intact:EBI-25401663	intact:EBI-1045965|uniprotkb:Q96DG4|uniprotkb:Q96MP7|ensembl:ENSP00000301011.5	psi-mi:a0a0h3l9i7_mycte(display_long)|uniprotkb:ERDMAN_2006(locus name)	psi-mi:zch18_human(display_long)|uniprotkb:NHN1(gene name synonym)|uniprotkb:Nuclear protein NHN1(gene name synonym)|uniprotkb:ZC3H18(gene name)|psi-mi:ZC3H18(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401928|imex:IM-27663-68	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR050109|interpro:IPR009057(Homeodomain-like)|interpro:IPR001647(Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal)|interpro:IPR036271|interpro:IPR025996|refseq:WP_003899034.1|mint:A0A0H3L9I7"	"refseq:NP_001281269.1|ensembl:ENSG00000158545.16(gene)|ensembl:ENST00000301011.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0016607""(nuclear speck)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0050779""(RNA destabilization)|go:""GO:0140262""(mRNA cap binding complex binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|interpro:IPR052647|mint:Q86VM9|refseq:NP_653205.3|panther:PTHR46582(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:+nfmZkrPEFtnvh6c6DD2Y0Ox+iE652616	rogid:H9lST8OLyCpyi5AWYqFYskL0ezI9606	intact-crc:2C3F5472B78A2BBE|rigid:wX5m871vQ5NFRnFnIEGG0jkuDDc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L9I7	uniprotkb:P68400	intact:EBI-25401663	intact:EBI-347804|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|ensembl:ENSP00000217244.3|ensembl:ENSP00000383076.2|ensembl:ENSP00000495248.1|ensembl:ENSP00000495422.1|ensembl:ENSP00000495902.1|ensembl:ENSP00000495912.1|ensembl:ENSP00000495998.1|ensembl:ENSP00000496569.1|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6	psi-mi:a0a0h3l9i7_mycte(display_long)|uniprotkb:ERDMAN_2006(locus name)	psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401928|imex:IM-27663-68	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR050109|interpro:IPR009057(Homeodomain-like)|interpro:IPR001647(Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal)|interpro:IPR036271|interpro:IPR025996|refseq:WP_003899034.1|mint:A0A0H3L9I7"	"ensembl:ENSG00000101266.19(gene)|ensembl:ENST00000217244.9(transcript)|ensembl:ENST00000400217.7(transcript)|ensembl:ENST00000643660.1(transcript)|ensembl:ENST00000645623.1(transcript)|ensembl:ENST00000646305.1(transcript)|ensembl:ENST00000646561.1(transcript)|ensembl:ENST00000646814.1(transcript)|ensembl:ENST00000647348.1(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005956""(protein kinase CK2 complex)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016301""(kinase activity)|go:""GO:0016605""(PML body)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048511""(rhythmic process)|go:""GO:0050821""(protein stabilization)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070822""(Sin3-type complex)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0075342""(symbiont-mediated disruption of host cell PML body)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1905337""(positive regulation of aggrephagy)|go:""GO:1905818""(regulation of chromosome separation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR045216|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:3PE1|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:4DGL|rcsb pdb:4FBX|rcsb pdb:4GRB|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:5CT0|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5OS7|rcsb pdb:5OS8|rcsb pdb:5OSL|rcsb pdb:5OSP|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5OT5|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OWL|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5ZN2|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|rcsb pdb:6A1C|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|rcsb pdb:6TLR|rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7A4Q|rcsb pdb:7AT5|rcsb pdb:7AY9|rcsb pdb:7AYA|rcsb pdb:7B8H|rcsb pdb:7B8I|rcsb pdb:7BU4|rcsb pdb:7L1X|rcsb pdb:7PSU|rcsb pdb:7QGB|rcsb pdb:7QGC|rcsb pdb:7QGD|rcsb pdb:7QGE|rcsb pdb:7QUX|rcsb pdb:7X4H|rcsb pdb:7Z39|rcsb pdb:7ZWE|rcsb pdb:7ZWG|rcsb pdb:7ZY0|rcsb pdb:7ZY2|rcsb pdb:7ZY5|rcsb pdb:7ZY8|rcsb pdb:7ZYD|rcsb pdb:7ZYK|rcsb pdb:7ZYO|rcsb pdb:7ZYR|rcsb pdb:8AE7|rcsb pdb:8AEC|rcsb pdb:8AEK|rcsb pdb:8AEM|rcsb pdb:8BGC|rcsb pdb:8C5Q|rcsb pdb:8C6L|rcsb pdb:8C6M|rcsb pdb:8C6N|rcsb pdb:8P05|rcsb pdb:8P06|rcsb pdb:8P07|rcsb pdb:8PVO|rcsb pdb:8PVP|rcsb pdb:8QQB|rcsb pdb:8QWY|rcsb pdb:8QWZ|rcsb pdb:9EPV|rcsb pdb:9EPW|rcsb pdb:9EPX|rcsb pdb:9EPY|rcsb pdb:9EPZ|rcsb pdb:9EQ0|rcsb pdb:9EQ1|rcsb pdb:9EZG|rcsb pdb:9FYF|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|reactome:R-HSA-9755511|reactome:R-HSA-9828806|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|efo:""Orphanet:528084""|panther:PTHR24054(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:+nfmZkrPEFtnvh6c6DD2Y0Ox+iE652616	rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606	intact-crc:2C3F5472B78A2BBE|rigid:wX5m871vQ5NFRnFnIEGG0jkuDDc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L9I7	uniprotkb:P67870	intact:EBI-25401663	intact:EBI-348169|uniprotkb:P07312|uniprotkb:P13862|ensembl:ENSP00000365025.2|ensembl:ENSP00000365026.2|ensembl:ENSP00000365042.3|ensembl:ENSP00000372919.2|ensembl:ENSP00000372925.4|ensembl:ENSP00000382980.1|ensembl:ENSP00000390900.2|ensembl:ENSP00000391038.1|ensembl:ENSP00000393756.1|ensembl:ENSP00000394855.1|ensembl:ENSP00000395275.1|ensembl:ENSP00000400188.2|ensembl:ENSP00000407018.2|ensembl:ENSP00000407379.1|ensembl:ENSP00000409510.1|ensembl:ENSP00000410802.1|ensembl:ENSP00000411322.1|ensembl:ENSP00000412520.1|ensembl:ENSP00000413469.1|ensembl:ENSP00000415237.2|ensembl:ENSP00000415303.2|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9	psi-mi:a0a0h3l9i7_mycte(display_long)|uniprotkb:ERDMAN_2006(locus name)	psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401928|imex:IM-27663-68	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR050109|interpro:IPR009057(Homeodomain-like)|interpro:IPR001647(Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal)|interpro:IPR036271|interpro:IPR025996|refseq:WP_003899034.1|mint:A0A0H3L9I7"	"ensembl:ENSG00000204435.15(gene)|ensembl:ENSG00000206406.9(gene)|ensembl:ENSG00000224398.7(gene)|ensembl:ENSG00000224774.7(gene)|ensembl:ENSG00000228875.8(gene)|ensembl:ENSG00000230700.11(gene)|ensembl:ENSG00000232960.12(gene)|ensembl:ENST00000375865.6(transcript)|ensembl:ENST00000375866.2(transcript)|ensembl:ENST00000375882.7(transcript)|ensembl:ENST00000383427.6(transcript)|ensembl:ENST00000383433.8(transcript)|ensembl:ENST00000400110.5(transcript)|ensembl:ENST00000412802.5(transcript)|ensembl:ENST00000418230.5(transcript)|ensembl:ENST00000422567.6(transcript)|ensembl:ENST00000429633.5(transcript)|ensembl:ENST00000431476.5(transcript)|ensembl:ENST00000436169.5(transcript)|ensembl:ENST00000443673.6(transcript)|ensembl:ENST00000448596.1(transcript)|ensembl:ENST00000451917.6(transcript)|ensembl:ENST00000452985.6(transcript)|ensembl:ENST00000453234.5(transcript)|ensembl:ENST00000454382.6(transcript)|ensembl:ENST00000454511.5(transcript)|ensembl:ENST00000455161.1(transcript)|ensembl:ENST00000458330.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005956""(protein kinase CK2 complex)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016605""(PML body)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032927""(positive regulation of activin receptor signaling pathway)|go:""GO:0033211""(adiponectin-activated signaling pathway)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051101""(regulation of DNA binding)|go:""GO:0060391""(positive regulation of SMAD protein signal transduction)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0075342""(symbiont-mediated disruption of host cell PML body)|go:""GO:1903901""(negative regulation of viral life cycle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:6Q38|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|reactome:R-HSA-9755511|reactome:R-HSA-9828806|refseq:NP_001269314.1|refseq:NP_001311.3|dip:DIP-131N|panther:PTHR11740(orthology-group)|efo:""Orphanet:178469"""	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:+nfmZkrPEFtnvh6c6DD2Y0Ox+iE652616	rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606	intact-crc:2C3F5472B78A2BBE|rigid:wX5m871vQ5NFRnFnIEGG0jkuDDc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L9I7	uniprotkb:P04066	intact:EBI-25401663	intact:EBI-2512153|ensembl:ENSP00000363603.3|uniprotkb:Q14335|uniprotkb:Q8NAC2|uniprotkb:Q3LID0|uniprotkb:Q14334|uniprotkb:B2RBG3	psi-mi:a0a0h3l9i7_mycte(display_long)|uniprotkb:ERDMAN_2006(locus name)	psi-mi:fuco_human(display_long)|uniprotkb:FUCA1(gene name)|psi-mi:FUCA1(display_short)|uniprotkb:Alpha-L-fucoside fucohydrolase 1(gene name synonym)|uniprotkb:Alpha-L-fucosidase I(gene name synonym)|uniprotkb:Nbla10230(orf name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401928|imex:IM-27663-68	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR050109|interpro:IPR009057(Homeodomain-like)|interpro:IPR001647(Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal)|interpro:IPR036271|interpro:IPR025996|refseq:WP_003899034.1|mint:A0A0H3L9I7"	"ensembl:ENSG00000179163.12(gene)|ensembl:ENST00000374479.4(transcript)|go:""GO:0004560""(alpha-L-fucosidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0006004""(fucose metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016139""(glycoside catabolic process)|go:""GO:0019377""(glycolipid catabolic process)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000933(""Glycoside hydrolase, family 29 (alpha-L-fucosidase)"")|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR016286(Alpha-L-fucosidase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018526|interpro:IPR031919|mint:P04066|rcsb pdb:7PLS|rcsb pdb:7PM4|reactome:R-HSA-6798695|reactome:R-HSA-975578|refseq:NP_000138.2|efo:""Orphanet:349""|panther:PTHR10030(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:+nfmZkrPEFtnvh6c6DD2Y0Ox+iE652616	rogid:hzGxBObvRAGMJxL+I9shJUo+nLg9606	intact-crc:2C3F5472B78A2BBE|rigid:wX5m871vQ5NFRnFnIEGG0jkuDDc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3L9I7	uniprotkb:P78527	intact:EBI-25401663	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420.3	psi-mi:a0a0h3l9i7_mycte(display_long)|uniprotkb:ERDMAN_2006(locus name)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)|uniprotkb:Ser-473 kinase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401928|imex:IM-27663-68	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR050109|interpro:IPR009057(Homeodomain-like)|interpro:IPR001647(Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal)|interpro:IPR036271|interpro:IPR025996|refseq:WP_003899034.1|mint:A0A0H3L9I7"	"efo:""Orphanet:317425""|ensembl:ENSG00000253729.9(gene)|ensembl:ENST00000314191.7(transcript)|go:""GO:0000460""(maturation of 5.8S rRNA)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0001756""(somitogenesis)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0002326""(B cell lineage commitment)|go:""GO:0002327""(immature B cell differentiation)|go:""GO:0002328""(pro-B cell differentiation)|go:""GO:0002360""(T cell lineage commitment)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0016020""(membrane)|go:""GO:0016233""(telomere capping)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0031648""(protein destabilization)|go:""GO:0032040""(small-subunit processome)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033152""(""immunoglobulin V(D)J recombination"")|go:""GO:0033153""(""T cell receptor V(D)J recombination"")|go:""GO:0034462""(small-subunit processome assembly)|go:""GO:0034511""(U3 snoRNA binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035234""(ectopic germ cell programmed cell death)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036211""(protein modification process)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045087""(innate immune response)|go:""GO:0045621""(positive regulation of lymphocyte differentiation)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0050678""(regulation of epithelial cell proliferation)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097681""(double-strand break repair via alternative nonhomologous end joining)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:0160049""(negative regulation of cGAS/STING signaling pathway)|go:""GO:1902036""(regulation of hematopoietic stem cell differentiation)|go:""GO:1905221""(positive regulation of platelet formation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|interpro:IPR045581|interpro:IPR046803|interpro:IPR046804|interpro:IPR050517|mint:P78527|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|rcsb pdb:7K11|rcsb pdb:7K19|rcsb pdb:7K1B|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7OTM|rcsb pdb:7OTP|rcsb pdb:7OTV|rcsb pdb:7OTW|rcsb pdb:7OTY|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7SUD|rcsb pdb:7TYR|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZ9|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|refseq:NP_001075109.1|refseq:NP_008835.5|dip:DIP-24186N|panther:PTHR11139(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/10	rogid:+nfmZkrPEFtnvh6c6DD2Y0Ox+iE652616	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	intact-crc:2C3F5472B78A2BBE|rigid:wX5m871vQ5NFRnFnIEGG0jkuDDc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:P25205	intact:EBI-25401952	intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940.2	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"ensembl:ENSG00000112118.20(gene)|ensembl:ENST00000596288.7(transcript)|go:""GO:0000727""(double-strand break repair via break-induced replication)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005658""(""alpha DNA polymerase:primase complex"")|go:""GO:0005813""(centrosome)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006271""(DNA strand elongation involved in DNA replication)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030174""(regulation of DNA-templated DNA replication initiation)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042555""(MCM complex)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071162""(CMG complex)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1902975""(mitotic DNA replication initiation)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:7W1Y|rcsb pdb:7W68|rcsb pdb:8B9D|rcsb pdb:8S09|rcsb pdb:8S0A|rcsb pdb:8S0B|rcsb pdb:8S0D|rcsb pdb:8S0E|rcsb pdb:8S0F|rcsb pdb:8W0E|rcsb pdb:8W0F|rcsb pdb:8W0G|rcsb pdb:8W0I|rcsb pdb:9CAQ|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_002379.3|refseq:NP_001257401.1|dip:DIP-31726N|panther:PTHR11630(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:O43865	intact:EBI-25401952	intact:EBI-2371423|uniprotkb:Q2TAJ6|uniprotkb:Q502W8|uniprotkb:Q5VSM0|uniprotkb:Q6P171|uniprotkb:Q96PK4|uniprotkb:Q9UG84|ensembl:ENSP00000358814.5|uniprotkb:B4E168	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	"psi-mi:sahh2_human(display_long)|uniprotkb:AHCYL1(gene name)|psi-mi:AHCYL1(display_short)|uniprotkb:DCAL(gene name synonym)|uniprotkb:XPVKONA(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 2(gene name synonym)|uniprotkb:DC-expressed AHCY-like molecule(gene name synonym)|uniprotkb:Putative adenosylhomocysteinase 2(gene name synonym)|uniprotkb:""IP(3)Rs binding protein released with IP(3)""(gene name synonym)|uniprotkb:IRBIT(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"ensembl:ENSG00000168710.18(gene)|ensembl:ENST00000369799.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0010765""(positive regulation of sodium ion transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0031440""(regulation of mRNA 3'-end processing)|go:""GO:0032412""(regulation of monoatomic ion transmembrane transporter activity)|go:""GO:0033353""(S-adenosylmethionine cycle)|go:""GO:0038166""(angiotensin-activated signaling pathway)|go:""GO:0042045""(epithelial fluid transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0044070""(regulation of monoatomic anion transport)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:O43865|rcsb pdb:3MTG|reactome:R-HSA-112043|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|refseq:NP_001229602.1|refseq:NP_001229603.1|refseq:NP_001229604.1|refseq:NP_001229605.1|refseq:NP_006612.2|panther:PTHR23420(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:uwZ+P9SdKadoVn01p/b8qHp6egk9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:Q13765	intact:EBI-25401952	intact:EBI-712216|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|intact:EBI-25601473|ensembl:ENSP00000349212.3|ensembl:ENSP00000377469.4|ensembl:ENSP00000446801.1|ensembl:ENSP00000447821.1|ensembl:ENSP00000503345.1|uniprotkb:F8VU71	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|ensembl:ENSG00000196531.14(gene)|ensembl:ENST00000356769.7(transcript)|ensembl:ENST00000393891.8(transcript)|ensembl:ENST00000546392.6(transcript)|ensembl:ENST00000552540.5(transcript)|ensembl:ENST00000678066.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003231""(cardiac ventricle development)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005854""(nascent polypeptide-associated complex)|go:""GO:0006412""(translation)|go:""GO:0010664""(negative regulation of striated muscle cell apoptotic process)|go:""GO:0015031""(protein transport)|go:""GO:0042060""(wound healing)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048633""(positive regulation of skeletal muscle tissue growth)|go:""GO:0048742""(regulation of skeletal muscle fiber development)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905551""(negative regulation of protein localization to endoplasmic reticulum)|go:""GO:2000138""(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|rcsb pdb:7QWQ|rcsb pdb:7QWR|rcsb pdb:7QWS|rcsb pdb:8P2K|rcsb pdb:9F1B|rcsb pdb:9F1C|rcsb pdb:9F1D|rcsb pdb:9FQ0|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:Q01130	intact:EBI-25401952	intact:EBI-627047|uniprotkb:B3KWD5|uniprotkb:B4DN89|uniprotkb:H0YG49|ensembl:ENSP00000353089.5|ensembl:ENSP00000376276.2|ensembl:ENSP00000391278.3|ensembl:ENSP00000462425.1|intact:EBI-21351483	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"ensembl:ENSG00000161547.17(gene)|ensembl:ENST00000359995.10(transcript)|ensembl:ENST00000392485.2(transcript)|ensembl:ENST00000452355.7(transcript)|ensembl:ENST00000585202.5(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005726""(perichromatin fibrils)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0033197""(response to vitamin E)|go:""GO:0035061""(interchromatin granule)|go:""GO:0036002""(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR051106|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N|efo:""Orphanet:98823""|efo:""Orphanet:98849""|efo:""Orphanet:98850""|panther:PTHR23147(orthology-group)|ensembl:ENSP00000353089.5|ensembl:ENSP00000376276.2|ensembl:ENSP00000391278.3|ensembl:ENST00000508921.7|ensembl:ENSP00000441780.2|ensembl:ENSP00000462425.1"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:P82979	intact:EBI-25401952	intact:EBI-347495|uniprotkb:Q9P066|uniprotkb:A8K393|ensembl:ENSP00000337632.3|ensembl:ENSP00000449409.1	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:sarnp_human(display_long)|uniprotkb:HSPC316(orf name)|uniprotkb:Cytokine-induced protein of 29 kDa(gene name synonym)|uniprotkb:SARNP(gene name)|psi-mi:SARNP(display_short)|uniprotkb:Proliferation-associated cytokine-inducible protein CIP29(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:Nuclear protein Hcc-1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"refseq:NP_149073.1|panther:PTHR46551(orthology-group)|ensembl:ENSG00000205323.9(gene)|ensembl:ENST00000336133.8(transcript)|ensembl:ENST00000546604.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000346""(transcription export complex)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006417""(regulation of translation)|go:""GO:0016607""(nuclear speck)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR036361|interpro:IPR052240|mint:P82979|rcsb pdb:2DO1|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:O/j7XYd9K3eQu1JS58FSsEyPRpE9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:Q15287	intact:EBI-25401952	intact:EBI-395959|uniprotkb:A8K1P0|uniprotkb:B4DDU8|uniprotkb:B4DZU7|uniprotkb:B7ZA17|uniprotkb:O75308|uniprotkb:Q32P25|uniprotkb:Q8WY42|uniprotkb:Q9NYG3|ensembl:ENSP00000301730.8|ensembl:ENSP00000315859.5|ensembl:ENSP00000380275.2|ensembl:ENSP00000457723.1|ensembl:ENSP00000457820.1	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:rnps1_human(display_long)|uniprotkb:SR-related protein LDC2(gene name synonym)|uniprotkb:RNPS1(gene name)|psi-mi:RNPS1(display_short)|uniprotkb:LDC2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"refseq:NP_006702.1|refseq:NP_542161.1|refseq:NP_001273554.1|refseq:NP_001273555.1|refseq:NP_001273556.1|refseq:XP_005255105.1|refseq:XP_005255106.1|ensembl:ENSG00000205937.12(gene)|ensembl:ENST00000301730.12(transcript)|ensembl:ENST00000320225.10(transcript)|ensembl:ENST00000397086.6(transcript)|ensembl:ENST00000565678.5(transcript)|ensembl:ENST00000568631.5(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0048025""(negative regulation of mRNA splicing, via spliceosome)|go:""GO:0061574""(ASAP complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034201|interpro:IPR035979|mint:Q15287|rcsb pdb:4A8X|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:XP_016878363.1|dip:DIP-32943N|panther:PTHR15481(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:nANu/nh/pD/F6dYE2Sa28OegPGs9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:Q9C0C9	intact:EBI-25401952	intact:EBI-2339946|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q9H6E6|ensembl:ENSP00000323687.6	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"refseq:NP_071349.3|ensembl:ENSG00000175931.13(gene)|ensembl:ENST00000319380.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|rcsb pdb:7UN3|rcsb pdb:7UN6|reactome:R-HSA-983168|panther:PTHR46116(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:Q9UQ35	intact:EBI-25401952	intact:EBI-1050142|uniprotkb:A6NKB9|uniprotkb:Q9UHA8|uniprotkb:Q9UQ36|uniprotkb:Q9UQ37|uniprotkb:Q9UQ38|uniprotkb:Q9UQ40|uniprotkb:O15038|uniprotkb:O94803|uniprotkb:Q6NSL3|uniprotkb:Q6PIM3|uniprotkb:Q6PK40|uniprotkb:Q8IW17|uniprotkb:Q96GY7|uniprotkb:Q9P0G1|uniprotkb:D3DU97|ensembl:ENSP00000301740.8|ensembl:ENSP00000461181.2	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:srrm2_human(display_long)|uniprotkb:Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa(gene name synonym)|uniprotkb:Splicing coactivator subunit SRm300(gene name synonym)|uniprotkb:300 kDa nuclear matrix antigen(gene name synonym)|uniprotkb:SRRM2(gene name)|psi-mi:SRRM2(display_short)|uniprotkb:KIAA0324(gene name synonym)|uniprotkb:SRL300(gene name synonym)|uniprotkb:SRM300(gene name synonym)|uniprotkb:HSPC075(orf name)|uniprotkb:Tax-responsive enhancer element-binding protein 803(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"efo:""Orphanet:652487""|ensembl:ENSG00000167978.19(gene)|ensembl:ENST00000301740.13(transcript)|ensembl:ENST00000576924.6(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0015030""(Cajal body)|go:""GO:0016607""(nuclear speck)|go:""GO:0070742""(C2H2 zinc finger domain binding)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR024945|rcsb pdb:7W59|interpro:IPR047490|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:9FMD|interpro:IPR051372|mint:Q9UQ35|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7DVQ|rcsb pdb:7QTT|reactome:R-HSA-72163|refseq:NP_057417.3|panther:PTHR34755(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:3yyPAOaCzKSCEg5guJSbq0MWrHI9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:P33992	intact:EBI-25401952	intact:EBI-359410|uniprotkb:O60785|uniprotkb:Q14578|uniprotkb:Q9BTJ4|uniprotkb:Q9BWL8|ensembl:ENSP00000216122.3	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:mcm5_human(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:CDC46 homolog(gene name synonym)|uniprotkb:P1-CDC46(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"panther:PTHR11630(orthology-group)|refseq:NP_006730.2|ensembl:ENSG00000100297.16(gene)|ensembl:ENST00000216122.9(transcript)|go:""GO:0000727""(double-strand break repair via break-induced replication)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030174""(regulation of DNA-templated DNA replication initiation)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042555""(MCM complex)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071162""(CMG complex)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|interpro:IPR054125|mint:P33992|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:7W1Y|rcsb pdb:7W68|rcsb pdb:8B9D|rcsb pdb:8S09|rcsb pdb:8S0A|rcsb pdb:8S0B|rcsb pdb:8S0D|rcsb pdb:8S0E|rcsb pdb:8S0F|rcsb pdb:8W0E|rcsb pdb:8W0F|rcsb pdb:8W0G|rcsb pdb:8W0I|rcsb pdb:9CAQ|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27578N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:WjJ4lSpADQFtwT0WnumbRHl/lPw9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:P49736	intact:EBI-25401952	intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056.7	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"efo:""Orphanet:90635""|panther:PTHR11630(orthology-group)|ensembl:ENSG00000073111.15(gene)|ensembl:ENST00000265056.12(transcript)|go:""GO:0000727""(double-strand break repair via break-induced replication)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005664""(nuclear origin of replication recognition complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006915""(apoptotic process)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030174""(regulation of DNA-templated DNA replication initiation)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042393""(histone binding)|go:""GO:0042555""(MCM complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071162""(CMG complex)|go:""GO:0071353""(cellular response to interleukin-4)|go:""GO:0090102""(cochlea development)|interpro:IPR041562|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1902975""(mitotic DNA replication initiation)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:7W1Y|rcsb pdb:7W68|rcsb pdb:8B9D|rcsb pdb:8S09|rcsb pdb:8S0A|rcsb pdb:8S0B|rcsb pdb:8S0D|rcsb pdb:8S0E|rcsb pdb:8S0F|rcsb pdb:8W0E|rcsb pdb:8W0F|rcsb pdb:8W0G|rcsb pdb:8W0I|rcsb pdb:8YJF|rcsb pdb:8YJM|rcsb pdb:9CAQ|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:O00203	intact:EBI-25401952	intact:EBI-1044383|uniprotkb:O00580|uniprotkb:Q7Z393|uniprotkb:Q9HD66|uniprotkb:E5RJ68|intact:EBI-10969499|ensembl:ENSP00000255194.7	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:ap3b1_human(display_long)|uniprotkb:Adaptor protein complex AP-3 subunit beta-1(gene name synonym)|uniprotkb:Beta-3A-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta-1 large chain(gene name synonym)|uniprotkb:AP3B1(gene name)|psi-mi:AP3B1(display_short)|uniprotkb:ADTB3A(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta-1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"efo:""Orphanet:664500""|dip:DIP-24208N|ensembl:ENSG00000132842.16(gene)|ensembl:ENST00000255194.11(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003016""(respiratory system process)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006954""(inflammatory response)|go:""GO:0007040""(lysosome organization)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0007596""(blood coagulation)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030131""(clathrin adaptor complex)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0030851""(granulocyte differentiation)|go:""GO:0032438""(melanosome organization)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0036211""(protein modification process)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046907""(intracellular transport)|go:""GO:0048007""(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0051138""(positive regulation of NK T cell differentiation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0090152""(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:""GO:0098773""(skin epidermis development)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990742""(microvesicle)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|interpro:IPR029394|mint:O00203|reactome:R-HSA-432722|reactome:R-HSA-6802952|refseq:NP_001258698.1|refseq:NP_003655.3|panther:PTHR11134(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:+06UuQo62p9ALS7DiX+yKg7YRyg9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:P20962	intact:EBI-25401952	intact:EBI-724050|ensembl:ENSP00000310088.7	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:ptms_human(display_long)|uniprotkb:PTMS(gene name)|psi-mi:PTMS(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"refseq:NP_002815.3|ensembl:ENSG00000159335.19(gene)|ensembl:ENST00000309083.8(transcript)|go:""GO:0002376""(immune system process)|go:""GO:0005634""(nucleus)|go:""GO:0006260""(DNA replication)|go:""GO:0042393""(histone binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P20962|panther:PTHR22745(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:iELnzobQCJMa28yQCYCaO4h6/nE9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:Q15154	intact:EBI-25401952	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|ensembl:ENSP00000327077.8|intact:EBI-16421643|intact:EBI-10961691	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"efo:""Orphanet:146""|ensembl:ENSG00000078674.20(gene)|ensembl:ENST00000325083.13(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001764""(neuron migration)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0007098""(centrosome cycle)|go:""GO:0016020""(membrane)|go:""GO:0022027""(interkinetic nuclear migration)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034451""(centriolar satellite)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0034454""(microtubule anchoring at centrosome)|go:""GO:0035176""(social behavior)|go:""GO:0035735""(intraciliary transport involved in cilium assembly)|go:""GO:0035869""(ciliary transition zone)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060271""(cilium assembly)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0140706""(protein-containing complex localization to centriolar satellite)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|rcsb pdb:7Q46|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001302437.1|refseq:NP_006188.3|refseq:XP_016868972.1|refseq:XP_016868973.1|refseq:XP_016868983.1|refseq:XP_016868984.1|refseq:XP_016868985.1|dip:DIP-42189N|panther:PTHR14164(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:gV7sfdY5uU0egRgqblpnK4TeGB09606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:Q9Y383	intact:EBI-25401952	intact:EBI-352851|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500|ensembl:ENSP00000347005.4	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|ensembl:ENSG00000146963.18(gene)|ensembl:ENST00000354926.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005685""(U1 snRNP)|go:""GO:0006376""(mRNA splice site recognition)|go:""GO:0016607""(nuclear speck)|go:""GO:0019899""(enzyme binding)|go:""GO:0071004""(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|dip:DIP-32513N|panther:PTHR12375(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:P33993	intact:EBI-25401952	intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288.5	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"efo:""Orphanet:2512""|ensembl:ENSG00000166508.19(gene)|ensembl:ENST00000303887.10(transcript)|go:""GO:0000727""(double-strand break repair via break-induced replication)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006271""(DNA strand elongation involved in DNA replication)|go:""GO:0006974""(DNA damage response)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030174""(regulation of DNA-templated DNA replication initiation)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042325""(regulation of phosphorylation)|go:""GO:0042555""(MCM complex)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071162""(CMG complex)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:7W1Y|rcsb pdb:7W68|rcsb pdb:8B9D|rcsb pdb:8S09|rcsb pdb:8S0A|rcsb pdb:8S0B|rcsb pdb:8S0D|rcsb pdb:8S0E|rcsb pdb:8S0F|rcsb pdb:8W0E|rcsb pdb:8W0F|rcsb pdb:8W0G|rcsb pdb:8W0I|rcsb pdb:9CAQ|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|dip:DIP-27580N|panther:PTHR11630(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:O60841	intact:EBI-25401952	intact:EBI-928530|uniprotkb:O95805|uniprotkb:Q9UF81|uniprotkb:Q9UMN7|uniprotkb:Q53RV7|uniprotkb:Q53SI8|ensembl:ENSP00000289371.5	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:if2p_human(display_long)|uniprotkb:EIF5B(gene name)|psi-mi:EIF5B(display_short)|uniprotkb:IF2(gene name synonym)|uniprotkb:KIAA0741(gene name synonym)|uniprotkb:Translation initiation factor IF-2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"refseq:NP_056988.3|ensembl:ENSG00000158417.12(gene)|ensembl:ENST00000289371.11(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0042255""(ribosome assembly)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR023115|interpro:IPR027417|interpro:IPR029459|interpro:IPR036925|mint:O60841|rcsb pdb:7TQL|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|reactome:R-HSA-72706|panther:PTHR43381(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:5rLXO0ZcDcwLGOM4ZGA4fvQJ33U9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:Q8IYB3	intact:EBI-25401952	intact:EBI-1055880|uniprotkb:O60585|uniprotkb:Q5VVN4|ensembl:ENSP00000326261.8	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:srrm1_human(display_long)|uniprotkb:SRRM1(gene name)|psi-mi:SRRM1(display_short)|uniprotkb:SRM160(gene name synonym)|uniprotkb:Ser/Arg-related nuclear matrix protein(gene name synonym)|uniprotkb:SR-related nuclear matrix protein of 160 kDa(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"refseq:NP_001290377.1|refseq:NP_001290378.1|refseq:NP_005830.2|ensembl:ENSG00000133226.19(gene)|ensembl:ENST00000323848.14(transcript)|go:""GO:0000375""(RNA splicing, via transesterification reactions)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0008380""(RNA splicing)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR036483|interpro:IPR052225|mint:Q8IYB3|rcsb pdb:1MP1|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|rcsb pdb:8I0P|rcsb pdb:8I0R|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418|reactome:R-HSA-9013422|panther:PTHR23148(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:x9vhX2HWCy5mm29U2xVXxj1GJw09606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:P78537	intact:EBI-25401952	intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537.1	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym)|uniprotkb:Protein acetyltransferase BLOC1S1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"refseq:NP_001478.2|go:""GO:0005829""(cytosol)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0009060""(aerobic respiration)|go:""GO:0016197""(endosomal transport)|go:""GO:0018394""(peptidyl-lysine acetylation)|go:""GO:0031083""(BLOC-1 complex)|go:""GO:0031175""(neuron projection development)|go:""GO:0032418""(lysosome localization)|go:""GO:0032438""(melanosome organization)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0051036""(regulation of endosome size)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0061733""(protein-lysine-acetyltransferase activity)|go:""GO:0062196""(regulation of lysosome size)|ensembl:ENSG00000135441.8(gene)|ensembl:ENST00000548925.6(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0098574""(cytoplasmic side of lysosomal membrane)|go:""GO:0099078""(BORC complex)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|panther:PTHR13073(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:lntB3izez0HoFLPpiAtPBayt+G49606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA42	uniprotkb:P20290	intact:EBI-25401952	intact:EBI-1054687|uniprotkb:Q13893|uniprotkb:Q76M56|uniprotkb:A8K510|ensembl:ENSP00000369965.3	psi-mi:a0a0h3la42_mycte(display_long)|uniprotkb:cfp17(gene name)|psi-mi:cfp17(display_short)|uniprotkb:ERDMAN_2017(locus name)	psi-mi:btf3_human(display_long)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401960|imex:IM-27663-48	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050923|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:A0A0H3LA42	"refseq:NP_001032726.1|refseq:NP_001198.2|ensembl:ENSG00000145741.17(gene)|ensembl:ENST00000380591.8(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005854""(nascent polypeptide-associated complex)|go:""GO:0015031""(protein transport)|go:""GO:1905551""(negative regulation of protein localization to endoplasmic reticulum)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|mint:P20290|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:7QWQ|rcsb pdb:7QWR|rcsb pdb:9F1B|rcsb pdb:9F1C|rcsb pdb:9F1D|rcsb pdb:9FQ0|panther:PTHR10351(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo652616	rogid:TU7PtK2KVrzmdfaTdWcHloiRZYg9606	intact-crc:86E9E069A5E23FFE|rigid:pYxc2WyDDrKnPWzIYBGmAgQYQGc	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA99	uniprotkb:P15104	intact:EBI-25402024	intact:EBI-746653|ensembl:ENSP00000307900.5|ensembl:ENSP00000344958.5|ensembl:ENSP00000356537.6|ensembl:ENSP00000398320.2|uniprotkb:Q499Y9|uniprotkb:Q5T9Z1|uniprotkb:Q7Z3W4|uniprotkb:Q8IZ17	psi-mi:a0a0h3la99_mycte(display_long)|uniprotkb:ERDMAN_2098(locus name)	psi-mi:glna_human(display_long)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:GLUL(gene name)|psi-mi:GLUL(display_short)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Palmitoyltransferase GLUL(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402028|imex:IM-27663-50	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:A0A0H3LA99	"ensembl:ENSG00000135821.20(gene)|ensembl:ENST00000311223.9(transcript)|ensembl:ENST00000331872.11(transcript)|ensembl:ENST00000339526.9(transcript)|ensembl:ENST00000417584.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0004356""(glutamine synthetase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006538""(glutamate catabolic process)|go:""GO:0006542""(glutamine biosynthetic process)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009749""(response to glucose)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0018345""(protein palmitoylation)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0044297""(cell body)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097386""(glial cell projection)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1904749""(regulation of protein localization to nucleolus)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|interpro:IPR050292|mint:P15104|rcsb pdb:2OJW|rcsb pdb:2QC8|rcsb pdb:7EVT|rcsb pdb:8DNU|reactome:R-HSA-210455|reactome:R-HSA-8964539|refseq:NP_001028216.1|refseq:NP_001028228.1|refseq:NP_002056.2|refseq:XP_006711341.1|efo:""Orphanet:71278""|dip:DIP-308N|panther:PTHR20852(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/17	rogid:aUAOId90XORxDvtrj1fBg7tpREs652616	rogid:UOOgfw1g+kmpsEx64pUbW9GfmYw9606	intact-crc:6C7570BD7C2544C3|rigid:G2t6/XLcMxrsOEA9gNexzXFgOAg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA99	uniprotkb:P49366	intact:EBI-25402024	intact:EBI-741925|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5|ensembl:ENSP00000210060.6	psi-mi:a0a0h3la99_mycte(display_long)|uniprotkb:ERDMAN_2098(locus name)	psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402028|imex:IM-27663-50	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:A0A0H3LA99	"refseq:NP_001193903.1|refseq:NP_001921.1|refseq:NP_037538.1|refseq:XP_011526072.1|ensembl:ENSG00000095059.17(gene)|ensembl:ENST00000210060.12(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0008216""(spermidine metabolic process)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008612""(peptidyl-lysine modification to peptidyl-hypusine)|go:""GO:0034038""(deoxyhypusine synthase activity)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0046203""(spermidine catabolic process)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|rcsb pdb:7A6S|rcsb pdb:7A6T|rcsb pdb:8A0E|rcsb pdb:8A0F|rcsb pdb:8A0G|reactome:R-HSA-204626|panther:PTHR11703(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/17	rogid:aUAOId90XORxDvtrj1fBg7tpREs652616	rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606	intact-crc:6C7570BD7C2544C3|rigid:G2t6/XLcMxrsOEA9gNexzXFgOAg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LA99	uniprotkb:P15311	intact:EBI-25402024	intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934.7|ensembl:ENSP00000356042.3	psi-mi:a0a0h3la99_mycte(display_long)|uniprotkb:ERDMAN_2098(locus name)	psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402028|imex:IM-27663-50	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	mint:A0A0H3LA99	"ensembl:ENSG00000092820.19(gene)|ensembl:ENST00000337147.11(transcript)|ensembl:ENST00000367075.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0001726""(ruffle)|go:""GO:0001772""(immunological synapse)|go:""GO:0001931""(uropod)|go:""GO:0001951""(intestinal D-glucose absorption)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005903""(brush border)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0008017""(microtubule binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010737""(protein kinase A signaling)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022614""(membrane to membrane docking)|go:""GO:0030033""(microvillus assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030175""(filopodium)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0031528""(microvillus membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0031982""(vesicle)|go:""GO:0032532""(regulation of microvillus length)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|go:""GO:0035088""(establishment or maintenance of apical/basal cell polarity)|go:""GO:0036064""(ciliary basal body)|go:""GO:0040018""(positive regulation of multicellular organism growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0042995""(cell projection)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0044548""(S100 protein binding)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045177""(apical part of cell)|go:""GO:0045296""(cadherin binding)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051018""(protein kinase A binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051660""(establishment of centrosome localization)|go:""GO:0061028""(establishment of endothelial barrier)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0071944""(cell periphery)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0072697""(protein localization to cell cortex)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098974""(postsynaptic actin cytoskeleton organization)|go:""GO:1902115""(regulation of organelle assembly)|go:""GO:1902896""(terminal web assembly)|go:""GO:1902966""(positive regulation of protein localization to early endosome)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903753""(negative regulation of p38MAPK cascade)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|interpro:IPR046810|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|rcsb pdb:7T1K|rcsb pdb:7T1L|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001104547.1|refseq:NP_003370.2|efo:""Orphanet:88616""|dip:DIP-38868N|panther:PTHR23281(orthology-group)|ensembl:ENSP00000338934.7|ensembl:ENSP00000356042.3"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/17	rogid:aUAOId90XORxDvtrj1fBg7tpREs652616	rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606	intact-crc:6C7570BD7C2544C3|rigid:G2t6/XLcMxrsOEA9gNexzXFgOAg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q9ULT8	uniprotkb:A0A0H3LA05	intact:EBI-310559|uniprotkb:Q6P445|uniprotkb:Q86VJ1|uniprotkb:Q96F34|uniprotkb:Q9UFZ7|uniprotkb:D3DS86|ensembl:ENSP00000382269.1|ensembl:ENSP00000450697.1	intact:EBI-25402037	psi-mi:hecd1_human(display_long)|uniprotkb:HECTD1(gene name)|psi-mi:HECTD1(display_short)|uniprotkb:KIAA1131(gene name synonym)|uniprotkb:HECT domain-containing protein 1(gene name synonym)|uniprotkb:E3 ligase for inhibin receptor(gene name synonym)	psi-mi:a0a0h3la05_mycte(display_long)|uniprotkb:cfp21(gene name)|psi-mi:cfp21(display_short)|uniprotkb:ERDMAN_2184(locus name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402047|imex:IM-27663-52	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000092148.14(gene)|ensembl:ENST00000399332.6(transcript)|ensembl:ENST00000553700.5(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0003170""(heart valve development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0016607""(nuclear speck)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0035904""(aorta development)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000569(HECT)|interpro:IPR002110(Ankyrin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010606(Mib-herc2)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR036770|interpro:IPR037252|interpro:IPR041200|interpro:IPR045322|mint:Q9ULT8|rcsb pdb:2DK3|rcsb pdb:2LC3|rcsb pdb:3DKM|reactome:R-HSA-983168|refseq:XP_005267559.2|refseq:NP_056197.3|dip:DIP-31669N|panther:PTHR45670(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0052689""(carboxylic ester hydrolase activity)|interpro:IPR029058|interpro:IPR000675(Cutinase)|interpro:IPR043579|interpro:IPR043580|mint:A0A0H3LA05"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:j1zlgEQjO02IyJ4P4tyisjiarXI9606	rogid:pWIaQlmJjVWFG0tVPM+QbWSEKoU652616	intact-crc:0511A9844614448D|rigid:wS+N5ZRFOsg5kl1FkgOsizGRQ5I	false	-	strep tag:c-c	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:Q9UNZ2	intact:EBI-25401874	intact:EBI-721577|uniprotkb:Q7Z533|uniprotkb:Q9H102|uniprotkb:Q9NVL9|uniprotkb:Q9UI06|uniprotkb:Q5JXA5|uniprotkb:B2RD74|uniprotkb:Q5JXA4|uniprotkb:A2A2L1|ensembl:ENSP00000216879.4	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:nsf1c_human(display_long)|uniprotkb:p97 cofactor p47(gene name synonym)|uniprotkb:NSFL1C(gene name)|psi-mi:NSFL1C(display_short)|uniprotkb:UBXN2C(gene name synonym)|uniprotkb:UBX domain-containing protein 2C(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"refseq:NP_001193665.1|refseq:NP_057227.2|refseq:NP_061327.2|ensembl:ENSG00000088833.18(gene)|ensembl:ENST00000216879.9(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005795""(Golgi stack)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007030""(Golgi organization)|go:""GO:0008289""(lipid binding)|go:""GO:0031468""(nuclear membrane reassembly)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046604""(positive regulation of mitotic centrosome separation)|go:""GO:0061025""(membrane fusion)|go:""GO:1904780""(negative regulation of protein localization to centrosome)|go:""GO:1990730""(VCP-NSFL1C complex)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR012989(SEP)|interpro:IPR029071|interpro:IPR036241|mint:Q9UNZ2|rcsb pdb:1SS6|rcsb pdb:8HRZ|reactome:R-HSA-9013407|dip:DIP-39611N|refseq:XP_006723657.1|panther:PTHR23333(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:LhK56TmbnfHvffJ2WUFlJJepje89606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:P47756	intact:EBI-25401874	intact:EBI-353595|uniprotkb:Q5U0L4|uniprotkb:Q8TB49|ensembl:ENSP00000264202.7|uniprotkb:Q9NUC4|uniprotkb:Q32Q68	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:capzb_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"refseq:NP_004921.1|ensembl:ENSG00000077549.19(gene)|ensembl:ENST00000264202.8(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003779""(actin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005903""(brush border)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030017""(sarcomere)|go:""GO:0030027""(lamellipodium)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0045296""(cadherin binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051490""(negative regulation of filopodium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071203""(WASH complex)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0120212""(sperm head-tail coupling apparatus)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47756|rcsb pdb:8F8Q|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9662360|reactome:R-HSA-983231|refseq:NP_001269091.1|panther:PTHR10619(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:48IQ1CJkjL9DdUW66uFlFKhRWxo9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:Q96GA3	intact:EBI-25401874	intact:EBI-2558389|uniprotkb:Q96JX8|ensembl:ENSP00000356548.5	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:ltv1_human(display_long)|uniprotkb:LTV1(gene name)|psi-mi:LTV1(display_short)|uniprotkb:C6orf93(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"refseq:NP_116249.2|ensembl:ENSG00000135521.9(gene)|ensembl:ENST00000367576.6(transcript)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0030688""(preribosome, small subunit precursor)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|interpro:IPR007307(Low temperature viability protein)|mint:Q96GA3|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:7WTT|rcsb pdb:7WTU|rcsb pdb:7WTW|rcsb pdb:7WTX|rcsb pdb:7WTZ|rcsb pdb:7WU0|reactome:R-HSA-6791226|panther:PTHR21531(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:Csfx8GS5hoclLY1BYki/uUKoSIM9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:P05387	intact:EBI-25401874	intact:EBI-352813|uniprotkb:Q6FG96|ensembl:ENSP00000322419.4|ensembl:ENSP00000431240.1	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:60S acidic ribosomal protein P2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"refseq:NP_000995.1|ensembl:ENSG00000177600.10(gene)|ensembl:ENST00000321153.9(transcript)|ensembl:ENST00000530797.6(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0002182""(cytoplasmic translational elongation)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0016020""(membrane)|go:""GO:0022625""(cytosolic large ribosomal subunit)|go:""GO:0070062""(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|panther:PTHR21141(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:Q9Y4P1	intact:EBI-25401874	intact:EBI-712014|uniprotkb:Q6ZUV8|uniprotkb:Q8WYM9|uniprotkb:Q96K07|uniprotkb:Q96K96|uniprotkb:Q96SZ1|uniprotkb:Q9Y2F2|uniprotkb:Q53NU4|uniprotkb:B7WNK2|ensembl:ENSP00000384259.3	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:atg4b_human(display_long)|uniprotkb:Autophagy-related protein 4 homolog B(gene name synonym)|uniprotkb:Autophagy-related cysteine endopeptidase 1(gene name synonym)|uniprotkb:AUT-like 1 cysteine endopeptidase(gene name synonym)|uniprotkb:ATG4B(gene name)|psi-mi:ATG4B(display_short)|uniprotkb:APG4B(gene name synonym)|uniprotkb:AUTL1(gene name synonym)|uniprotkb:KIAA0943(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"refseq:NP_037457.3|refseq:NP_847896.1|ensembl:ENSG00000168397.17(gene)|ensembl:ENST00000404914.8(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0000423""(mitophagy)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0006914""(autophagy)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0015031""(protein transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0016237""(microautophagy)|go:""GO:0016485""(protein processing)|go:""GO:0019786""(protein-phosphatidylethanolamide deconjugating activity)|go:""GO:0031173""(otolith mineralization completed early in development)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034497""(protein localization to phagophore assembly site)|go:""GO:0034727""(piecemeal microautophagy of the nucleus)|go:""GO:0035973""(aggrephagy)|go:""GO:0051697""(protein delipidation)|go:""GO:0097110""(scaffold protein binding)|interpro:IPR005078(Peptidase C54)|interpro:IPR038765|interpro:IPR046792|interpro:IPR046793|mint:Q9Y4P1|rcsb pdb:2CY7|rcsb pdb:2D1I|rcsb pdb:2Z0D|rcsb pdb:2Z0E|rcsb pdb:2ZZP|rcsb pdb:5LXH|rcsb pdb:5LXI|reactome:R-HSA-1632852|panther:PTHR22624(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:xSDsMshJik2bdLQ06b0kErCLxyM9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:P05388	intact:EBI-25401874	intact:EBI-354101|uniprotkb:Q9BVK4|ensembl:ENSP00000339027.3|ensembl:ENSP00000376299.4|ensembl:ENSP00000449328.1|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|intact:EBI-21359026	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:60S acidic ribosomal protein P0(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157.16(gene)|ensembl:ENST00000228306.8(transcript)|ensembl:ENST00000392514.9(transcript)|ensembl:ENST00000551150.5(transcript)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0022625""(cytosolic large ribosomal subunit)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0030425""(dendrite)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070180""(large ribosomal subunit rRNA binding)|go:""GO:0071353""(cellular response to interleukin-4)|go:""GO:0098794""(postsynapse)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|interpro:IPR050323|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G6J|rcsb pdb:8K2C|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8YOO|rcsb pdb:8YOP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|panther:PTHR45699(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:P55072	intact:EBI-25401874	intact:EBI-355164|uniprotkb:Q969G7|intact:EBI-10175326|uniprotkb:V9HW80|ensembl:ENSP00000351777.6|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	"psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:HEL-220(gene name synonym)|uniprotkb:HEL-S-70(gene name synonym)|uniprotkb:""15S Mg(2+)-ATPase p97 subunit""(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"ensembl:ENSG00000165280.18(gene)|ensembl:ENST00000358901.11(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006734""(NADH metabolic process)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006914""(autophagy)|go:""GO:0006974""(DNA damage response)|go:""GO:0008289""(lipid binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0010918""(positive regulation of mitochondrial membrane potential)|go:""GO:0016236""(macroautophagy)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019079""(viral genome replication)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0019985""(translesion synthesis)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032510""(endosome to lysosome transport via multivesicular body sorting pathway)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034098""(VCP-NPL4-UFD1 AAA ATPase complex)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035617""(stress granule disassembly)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036297""(interstrand cross-link repair)|go:""GO:0036435""(K48-linked polyubiquitin modification-dependent protein binding)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036513""(Derlin-1 retrotranslocation complex)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043531""(ADP binding)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050807""(regulation of synapse organization)|go:""GO:0051228""(mitotic spindle disassembly)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070842""(aggresome assembly)|go:""GO:0071218""(cellular response to misfolded protein)|go:""GO:0072389""(flavin adenine dinucleotide catabolic process)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0106300""(protein-DNA covalent cross-linking repair)|go:""GO:0120186""(negative regulation of protein localization to chromatin)|go:""GO:0140036""(ubiquitin-modified protein reader activity)|go:""GO:0140455""(cytoplasm protein quality control)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903006""(positive regulation of protein K63-linked deubiquitination)|go:""GO:1903007""(positive regulation of Lys63-specific deubiquitinase activity)|go:""GO:1903715""(regulation of aerobic respiration)|go:""GO:1903843""(cellular response to arsenite ion)|go:""GO:1903862""(positive regulation of oxidative phosphorylation)|go:""GO:1904288""(BAT3 complex binding)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1904949""(ATPase complex)|go:""GO:1905634""(regulation of protein localization to chromatin)|go:""GO:1990381""(ubiquitin-specific protease binding)|go:""GO:1990730""(VCP-NSFL1C complex)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001171""(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|interpro:IPR050168|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|rcsb pdb:7BP9|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|rcsb pdb:7K56|rcsb pdb:7K57|rcsb pdb:7K59|rcsb pdb:7L5W|rcsb pdb:7L5X|rcsb pdb:7LMY|rcsb pdb:7LMZ|rcsb pdb:7LN0|rcsb pdb:7LN1|rcsb pdb:7LN2|rcsb pdb:7LN3|rcsb pdb:7LN4|rcsb pdb:7LN5|rcsb pdb:7LN6|rcsb pdb:7MDM|rcsb pdb:7MDO|rcsb pdb:7MHS|rcsb pdb:7OAT|rcsb pdb:7PUX|rcsb pdb:7R7S|rcsb pdb:7R7T|rcsb pdb:7R7U|rcsb pdb:7RL6|rcsb pdb:7RL7|rcsb pdb:7RL9|rcsb pdb:7RLA|rcsb pdb:7RLB|rcsb pdb:7RLC|rcsb pdb:7RLD|rcsb pdb:7RLF|rcsb pdb:7RLG|rcsb pdb:7RLH|rcsb pdb:7RLI|rcsb pdb:7RLJ|rcsb pdb:7VCS|rcsb pdb:7VCT|rcsb pdb:7VCU|rcsb pdb:7VCV|rcsb pdb:7VCX|rcsb pdb:7Y4W|rcsb pdb:7Y53|rcsb pdb:7Y59|rcsb pdb:8B5R|rcsb pdb:8FCL|rcsb pdb:8FCM|rcsb pdb:8FCN|rcsb pdb:8FCO|rcsb pdb:8FCP|rcsb pdb:8FCQ|rcsb pdb:8FCR|rcsb pdb:8FCT|rcsb pdb:8HL7|rcsb pdb:8HRZ|rcsb pdb:8KG2|rcsb pdb:8OOI|rcsb pdb:8PQX|rcsb pdb:8R0E|rcsb pdb:8RS9|rcsb pdb:8RSB|rcsb pdb:8RSC|rcsb pdb:8UV2|rcsb pdb:8UVO|rcsb pdb:8UVP|rcsb pdb:8UVQ|rcsb pdb:8VKU|rcsb pdb:8VLS|rcsb pdb:8VOV|rcsb pdb:8YKA|rcsb pdb:9BOQ|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-8951664|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|reactome:R-HSA-9755511|refseq:NP_009057.1|efo:""Orphanet:100070""|efo:""Orphanet:275864""|efo:""Orphanet:275872""|efo:""Orphanet:329475""|efo:""Orphanet:329478""|efo:""Orphanet:435387""|efo:""Orphanet:52430""|efo:""Orphanet:803""|dip:DIP-33543N|panther:PTHR23077(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:Q96ST2	intact:EBI-25401874	intact:EBI-2515615|uniprotkb:Q2TB65|uniprotkb:Q9NV97|uniprotkb:Q96MI7|uniprotkb:Q9NWH8|uniprotkb:Q6P157|uniprotkb:Q8N3E8|ensembl:ENSP00000295321.4	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:iws1_human(display_long)|uniprotkb:IWS1(gene name)|psi-mi:IWS1(display_short)|uniprotkb:IWS1L(gene name synonym)|uniprotkb:IWS1-like protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"refseq:NP_060439.2|ensembl:ENSG00000163166.15(gene)|ensembl:ENST00000295321.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0010793""(regulation of mRNA export from nucleus)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0050684""(regulation of mRNA processing)|go:""GO:0140673""(transcription elongation-coupled chromatin remodeling)|interpro:IPR017923|interpro:IPR035441|interpro:IPR051037|mint:Q96ST2|rcsb pdb:6EMR|rcsb pdb:6ZV1|rcsb pdb:6ZV4|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|panther:PTHR46010(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:G7KjbkwlfWdg2VufnJfRBiS/yUs9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:Q5T1M5	intact:EBI-25401874	intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256.3|ensembl:ENSP00000416158.2	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321.10(gene)|ensembl:ENST00000238256.8(transcript)|ensembl:ENST00000446284.6(transcript)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0003779""(actin binding)|go:""GO:0005769""(early endosome)|go:""GO:0006897""(endocytosis)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030426""(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR046357|mint:Q5T1M5|panther:PTHR44927(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:Q9Y4B6	intact:EBI-25401874	intact:EBI-1996353|uniprotkb:Q2YD74|uniprotkb:Q8TBD9|uniprotkb:Q9HCA1|uniprotkb:Q9UG37|ensembl:ENSP00000393183.2|ensembl:ENSP00000506880.1|intact:EBI-2559078|intact:EBI-28988191	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:dcaf1_human(display_long)|uniprotkb:DCAF1(gene name)|psi-mi:DCAF1(display_short)|uniprotkb:HIV-1 Vpr-binding protein(gene name synonym)|uniprotkb:KIAA0800(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:VPRBP(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"go:""GO:1990244""(histone H2AT120 kinase activity)|refseq:NP_001165375.1|refseq:NP_055518.1|refseq:XP_011532575.1|refseq:XP_011532576.1|refseq:XP_011532577.1|refseq:XP_011532578.1|refseq:XP_011532579.1|ensembl:ENSG00000145041.17(gene)|ensembl:ENST00000423656.5(transcript)|ensembl:ENST00000684031.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0033151""(""V(D)J recombination"")|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035212""(cell competition in a multicellular organism)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|rcsb pdb:4P7I|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|mint:Q9Y4B6|rcsb pdb:3WA0|rcsb pdb:4CC9|rcsb pdb:4PXW|rcsb pdb:4Z8L|rcsb pdb:5AJA|rcsb pdb:5JK7|rcsb pdb:6N45|rcsb pdb:6ZUE|rcsb pdb:6ZX9|rcsb pdb:7OKQ|rcsb pdb:7SSE|rcsb pdb:7UFV|rcsb pdb:7V7B|rcsb pdb:7V7C|rcsb pdb:8F8E|rcsb pdb:8OG5|rcsb pdb:8OG6|rcsb pdb:8OG7|rcsb pdb:8OG8|rcsb pdb:8OG9|rcsb pdb:8OGA|rcsb pdb:8OGB|rcsb pdb:8OGC|rcsb pdb:8OO5|rcsb pdb:8OOD|rcsb pdb:9BHR|rcsb pdb:9BHS|rcsb pdb:9C1Q|reactome:R-HSA-983168|refseq:XP_005276810.1|refseq:XP_005276812.1|panther:PTHR13129(orthology-group)|refseq:XP_016863035.1|refseq:XP_016863036.1|refseq:XP_016863037.1|refseq:XP_016863038.1|refseq:XP_016863039.1|dip:DIP-47048N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:qs3qG0MM135EE/DjC1S/gCLRFhc9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:Q12768	intact:EBI-25401874	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016.7	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"ensembl:ENSG00000164961.16(gene)|ensembl:ENST00000318410.12(transcript)|go:""GO:0001556""(oocyte maturation)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0007032""(endosome organization)|go:""GO:0007040""(lysosome organization)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0015031""(protein transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0040038""(polar body extrusion after meiotic divisions)|go:""GO:0043025""(neuronal cell body)|go:""GO:0051125""(regulation of actin nucleation)|go:""GO:0071203""(WASH complex)|go:""GO:0090306""(meiotic spindle assembly)|go:""GO:0097494""(regulation of vesicle size)|go:""GO:0140285""(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:NP_055661.3|refseq:XP_016869602.1|efo:""Orphanet:100989""|efo:""Orphanet:7""|panther:PTHR15691(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:O43719	intact:EBI-25401874	intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|ensembl:ENSP00000218364.4|ensembl:ENSP00000442699.1|intact:EBI-28971035	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short)|uniprotkb:HIV Tat-specific factor 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"refseq:NP_001156752.1|refseq:NP_055315.2|ensembl:ENSG00000102241.12(gene)|refseq:XP_005262461.1|rcsb pdb:6Y5Q|rcsb pdb:7EVO|ensembl:ENST00000218364.5(transcript)|ensembl:ENST00000535601.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005684""(U2-type spliceosomal complex)|go:""GO:0005686""(U2 snRNP)|go:""GO:0035861""(site of double-strand break)|go:""GO:0140463""(chromatin-protein adaptor activity)|go:""GO:0160004""(poly-ADP-D-ribose modification-dependent protein binding)|go:""GO:1903241""(U2-type prespliceosome assembly)|go:""GO:1990166""(protein localization to site of double-strand break)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:7Q3L|rcsb pdb:8HK1|reactome:R-HSA-72163|dip:DIP-42095N|panther:PTHR15608(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:PttL+7D+505QAmcHRGNsc40haPY9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LAC5	uniprotkb:P06748	intact:EBI-25401874	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402053|imex:IM-27663-70	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:B11227DAAA4F56AF|rigid:7KgSRdLAn/UKfD6Ql92SVWLwfEk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBU6	uniprotkb:Q9NTK5	intact:EBI-25402072	intact:EBI-766468|uniprotkb:Q5BJD7|uniprotkb:Q8NCI8|uniprotkb:Q96CU1|uniprotkb:Q96SV2|uniprotkb:Q9P1D3|uniprotkb:Q9UNY9|uniprotkb:Q9Y6G4|ensembl:ENSP00000284719.3|uniprotkb:D7EHM2	psi-mi:a0a0h3lbu6_mycte(display_long)|uniprotkb:ERDMAN_2717(locus name)	psi-mi:ola1_human(display_long)|uniprotkb:GTPBP9(gene name synonym)|uniprotkb:GTP-binding protein 9(gene name synonym)|uniprotkb:OLA1(gene name)|psi-mi:OLA1(display_short)|uniprotkb:PTD004(orf name)|uniprotkb:PRO2455(orf name)|uniprotkb:DNA damage-regulated overexpressed in cancer 45(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402078|imex:IM-27663-54	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052892|interpro:IPR029471|interpro:IPR003615(HNH nuclease)|mint:A0A0H3LBU6	"refseq:NP_001011708.1|refseq:NP_037473.3|dip:DIP-34591N|ensembl:ENSG00000138430.16(gene)|ensembl:ENST00000284719.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR004095(TGS)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR023192|interpro:IPR027417|interpro:IPR031167|interpro:IPR041706|mint:Q9NTK5|rcsb pdb:2OHF|reactome:R-HSA-114608|panther:PTHR23305(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:TwEFubiRQBJZQJeZgeiegVcK8cs652616	rogid:aQk5XBcKpx1YSW4mHtyRsTpimvk9606	intact-crc:5BBF80C8111703AA|rigid:osyT+kXn2LROWDw5US5nL9twBHY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBU6	uniprotkb:P49411	intact:EBI-25402072	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439.3	psi-mi:a0a0h3lbu6_mycte(display_long)|uniprotkb:ERDMAN_2717(locus name)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402078|imex:IM-27663-54	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052892|interpro:IPR029471|interpro:IPR003615(HNH nuclease)|mint:A0A0H3LBU6	"efo:""Orphanet:254925""|ensembl:ENSG00000178952.11(gene)|ensembl:ENST00000313511.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045202""(synapse)|go:""GO:0045471""(response to ethanol)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070125""(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|interpro:IPR050055|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|reactome:R-HSA-9754560|refseq:NP_003312.3|refseq:XP_016879108.1|panther:PTHR43721(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:TwEFubiRQBJZQJeZgeiegVcK8cs652616	rogid:gmW0HIoZ+8MccQHJ44Lcu2uwCss9606	intact-crc:5BBF80C8111703AA|rigid:osyT+kXn2LROWDw5US5nL9twBHY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBU6	uniprotkb:Q9Y5L4	intact:EBI-25402072	intact:EBI-1057344|uniprotkb:P62206|uniprotkb:Q9UHL8|uniprotkb:Q9WTL1|ensembl:ENSP00000215570.2	psi-mi:a0a0h3lbu6_mycte(display_long)|uniprotkb:ERDMAN_2717(locus name)	psi-mi:tim13_human(display_long)|uniprotkb:TIMM13(gene name)|psi-mi:TIMM13(display_short)|uniprotkb:TIM13B(gene name synonym)|uniprotkb:TIMM13A(gene name synonym)|uniprotkb:TIMM13B(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402078|imex:IM-27663-54	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052892|interpro:IPR029471|interpro:IPR003615(HNH nuclease)|mint:A0A0H3LBU6	"refseq:NP_036590.1|ensembl:ENSG00000099800.8(gene)|ensembl:ENST00000215570.8(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042719""(mitochondrial intermembrane space protein transporter complex)|go:""GO:0045039""(protein insertion into mitochondrial inner membrane)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|mint:Q9Y5L4|reactome:R-HSA-1268020|panther:PTHR19338(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:TwEFubiRQBJZQJeZgeiegVcK8cs652616	rogid:kFNYBvKwUM0JECXq9FjvYv55JAM9606	intact-crc:5BBF80C8111703AA|rigid:osyT+kXn2LROWDw5US5nL9twBHY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBU6	uniprotkb:P56192	intact:EBI-25402072	intact:EBI-355848|uniprotkb:Q14895|uniprotkb:Q53H14|uniprotkb:Q96A15|uniprotkb:Q96BZ0|uniprotkb:Q9NSE0|ensembl:ENSP00000262027.5|uniprotkb:B3KVK7	psi-mi:a0a0h3lbu6_mycte(display_long)|uniprotkb:ERDMAN_2717(locus name)	psi-mi:symc_human(display_long)|uniprotkb:MARS1(gene name)|psi-mi:MARS1(display_short)|uniprotkb:MARS(gene name synonym)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402078|imex:IM-27663-54	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052892|interpro:IPR029471|interpro:IPR003615(HNH nuclease)|mint:A0A0H3LBU6	"efo:""Orphanet:397735""|efo:""Orphanet:401835""|efo:""Orphanet:440427""|ensembl:ENSG00000166986.15(gene)|ensembl:ENST00000262027.10(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0004825""(methionine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006418""(tRNA aminoacylation for protein translation)|go:""GO:0006431""(methionyl-tRNA aminoacylation)|go:""GO:0009303""(rRNA transcription)|go:""GO:0016020""(membrane)|go:""GO:0017101""(aminoacyl-tRNA synthetase multienzyme complex)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR000738(WHEP-TRS)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413(""Aminoacyl-tRNA synthetase, class I (M)"")|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR036282|interpro:IPR041598|interpro:IPR041872|mint:P56192|rcsb pdb:2DJV|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5GL7|rcsb pdb:5GOY|rcsb pdb:5Y6L|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-9856649|refseq:NP_004981.2|dip:DIP-38164N|panther:PTHR45765(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:TwEFubiRQBJZQJeZgeiegVcK8cs652616	rogid:qNZ6XqndlF5KRn/TWFDb5T1GjEc9606	intact-crc:5BBF80C8111703AA|rigid:osyT+kXn2LROWDw5US5nL9twBHY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBU6	uniprotkb:Q9UPY3	intact:EBI-25402072	intact:EBI-395506|uniprotkb:O95943|uniprotkb:Q9UQ02|uniprotkb:A7E2D3|uniprotkb:E0AD28|uniprotkb:B3KRG4|ensembl:ENSP00000343745.3|ensembl:ENSP00000376783.1|ensembl:ENSP00000433060.3|ensembl:ENSP00000433926.2|ensembl:ENSP00000435681.1|ensembl:ENSP00000437256.1|ensembl:ENSP00000502730.2	psi-mi:a0a0h3lbu6_mycte(display_long)|uniprotkb:ERDMAN_2717(locus name)	psi-mi:dicer_human(display_long)|uniprotkb:DICER1(gene name)|psi-mi:DICER1(display_short)|uniprotkb:DICER(gene name synonym)|uniprotkb:HERNA(gene name synonym)|uniprotkb:KIAA0928(gene name synonym)|uniprotkb:Helicase with RNase motif(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402078|imex:IM-27663-54	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052892|interpro:IPR029471|interpro:IPR003615(HNH nuclease)|mint:A0A0H3LBU6	"ensembl:ENSG00000100697.17(gene)|ensembl:ENST00000343455.8(transcript)|ensembl:ENST00000393063.6(transcript)|ensembl:ENST00000526495.6(transcript)|ensembl:ENST00000527414.5(transcript)|ensembl:ENST00000529720.2(transcript)|ensembl:ENST00000531162.7(transcript)|ensembl:ENST00000674628.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0004525""(ribonuclease III activity)|go:""GO:0004530""(deoxyribonuclease I activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006309""(apoptotic DNA fragmentation)|go:""GO:0010586""(miRNA metabolic process)|go:""GO:0010626""(negative regulation of Schwann cell proliferation)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016078""(tRNA decay)|go:""GO:0016442""(RISC complex)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021675""(nerve development)|go:""GO:0030422""(siRNA processing)|go:""GO:0031054""(pre-miRNA processing)|go:""GO:0031643""(positive regulation of myelination)|go:""GO:0032290""(peripheral nervous system myelin formation)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0035196""(miRNA processing)|go:""GO:0035197""(siRNA binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070578""(RISC-loading complex)|go:""GO:0070883""(pre-miRNA binding)|go:""GO:0070922""(RISC complex assembly)|go:""GO:0098795""(global gene silencing by mRNA cleavage)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|interpro:IPR048512|interpro:IPR048513|mint:Q9UPY3|rcsb pdb:2EB1|rcsb pdb:4NGB|rcsb pdb:4NGC|rcsb pdb:4NGD|rcsb pdb:4NGF|rcsb pdb:4NGG|rcsb pdb:4NH3|rcsb pdb:4NH5|rcsb pdb:4NH6|rcsb pdb:4NHA|rcsb pdb:4WYQ|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:7XW2|rcsb pdb:7XW3|reactome:R-HSA-203927|reactome:R-HSA-426486|reactome:R-HSA-9708296|reactome:R-HSA-9820841|reactome:R-HSA-9824594|refseq:NP_001182502.1|refseq:NP_001258211.1|refseq:NP_001278557.1|refseq:NP_085124.2|refseq:NP_803187.1|refseq:XP_011534901.1|refseq:XP_011534902.1|refseq:XP_011534903.1|refseq:XP_011534904.1|refseq:XP_016876609.1|refseq:XP_016876610.1|efo:""Orphanet:276399""|efo:""Orphanet:284343""|efo:""Orphanet:404476""|efo:""Orphanet:99757""|efo:""Orphanet:99914""|efo:""Orphanet:99915""|efo:""Orphanet:99916""|dip:DIP-29664N|panther:PTHR14950(orthology-group)|ensembl:ENSP00000343745.3|ensembl:ENSP00000376783.1|ensembl:ENSP00000437256.1|ensembl:ENSP00000435681.1|ensembl:ENSP00000433926.2|ensembl:ENSP00000433060.3|ensembl:ENST00000541352.5|ensembl:ENSP00000444719.1|ensembl:ENSP00000502730.2"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:TwEFubiRQBJZQJeZgeiegVcK8cs652616	rogid:RhSXQEEvS9b0IOvnrPYhRd0MzI09606	intact-crc:5BBF80C8111703AA|rigid:osyT+kXn2LROWDw5US5nL9twBHY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBU6	uniprotkb:O60220	intact:EBI-25402072	intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993.3	psi-mi:a0a0h3lbu6_mycte(display_long)|uniprotkb:ERDMAN_2717(locus name)	psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402078|imex:IM-27663-54	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052892|interpro:IPR029471|interpro:IPR003615(HNH nuclease)|mint:A0A0H3LBU6	"ensembl:ENSG00000126953.8(gene)|ensembl:ENST00000372902.4(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0007399""(nervous system development)|go:""GO:0042719""(mitochondrial intermembrane space protein transporter complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0045039""(protein insertion into mitochondrial inner membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|mint:O60220|reactome:R-HSA-1268020|refseq:NP_004076.1|efo:""Orphanet:52368""|panther:PTHR19338(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:TwEFubiRQBJZQJeZgeiegVcK8cs652616	rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606	intact-crc:5BBF80C8111703AA|rigid:osyT+kXn2LROWDw5US5nL9twBHY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBU6	uniprotkb:Q13155	intact:EBI-25402072	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029.3|uniprotkb:F8W950|intact:EBI-21359480	psi-mi:a0a0h3lbu6_mycte(display_long)|uniprotkb:ERDMAN_2717(locus name)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402078|imex:IM-27663-54	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052892|interpro:IPR029471|interpro:IPR003615(HNH nuclease)|mint:A0A0H3LBU6	"refseq:NP_006294.2|dip:DIP-34421N|ensembl:ENSG00000106305.10(gene)|ensembl:ENST00000223029.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0006915""(apoptotic process)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017101""(aminoacyl-tRNA synthetase multienzyme complex)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060510""(type II pneumocyte differentiation)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|rcsb pdb:8J9S|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-9856649|refseq:NP_001313536.1|panther:PTHR13438(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:TwEFubiRQBJZQJeZgeiegVcK8cs652616	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	intact-crc:5BBF80C8111703AA|rigid:osyT+kXn2LROWDw5US5nL9twBHY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBU6	uniprotkb:P07814	intact:EBI-25402072	intact:EBI-355315|uniprotkb:Q5H9S5|uniprotkb:Q6PD57|uniprotkb:Q86X73|uniprotkb:A0AVA9|uniprotkb:Q05BP6|uniprotkb:Q05DF8|uniprotkb:Q5DSM1|uniprotkb:B9EGH3|ensembl:ENSP00000355890.3	psi-mi:a0a0h3lbu6_mycte(display_long)|uniprotkb:ERDMAN_2717(locus name)	psi-mi:syep_human(display_long)|uniprotkb:EPRS1(gene name)|psi-mi:EPRS1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 32 protein(gene name synonym)|uniprotkb:EPRS(gene name synonym)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Glutamatyl-prolyl-tRNA synthetase(gene name synonym)|uniprotkb:PARS(gene name synonym)|uniprotkb:QARS(gene name synonym)|uniprotkb:QPRS(gene name synonym)|uniprotkb:PIG32(orf name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402078|imex:IM-27663-54	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052892|interpro:IPR029471|interpro:IPR003615(HNH nuclease)|mint:A0A0H3LBU6	"refseq:NP_004437.2|ensembl:ENSG00000136628.18(gene)|ensembl:ENST00000366923.8(transcript)|go:""GO:0004818""(glutamate-tRNA ligase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006418""(tRNA aminoacylation for protein translation)|go:""GO:0006424""(glutamyl-tRNA aminoacylation)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0017101""(aminoacyl-tRNA synthetase multienzyme complex)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0051020""(GTPase binding)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0097452""(GAIT complex)|go:""GO:0140212""(regulation of long-chain fatty acid import into cell)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|interpro:IPR045864|interpro:IPR049437|interpro:IPR053836|mint:P07814|rcsb pdb:1FYJ|rcsb pdb:4HVC|rcsb pdb:4K86|rcsb pdb:4K87|rcsb pdb:4K88|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5BMU|rcsb pdb:5V58|rcsb pdb:5VAD|rcsb pdb:5Y6L|rcsb pdb:6IY6|rcsb pdb:7BBU|rcsb pdb:7F98|rcsb pdb:7F99|rcsb pdb:7F9A|rcsb pdb:7F9B|rcsb pdb:7F9C|rcsb pdb:7F9D|rcsb pdb:7OSY|rcsb pdb:7OSZ|rcsb pdb:7OT0|rcsb pdb:7OT1|rcsb pdb:7OT2|rcsb pdb:7OT3|rcsb pdb:7X09|rcsb pdb:7X1O|rcsb pdb:7Y1H|rcsb pdb:7Y1W|rcsb pdb:7Y28|rcsb pdb:7Y3S|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-6782315|reactome:R-HSA-9856649|dip:DIP-40825N|panther:PTHR43382(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:TwEFubiRQBJZQJeZgeiegVcK8cs652616	rogid:67nL6JkhNTSttOucQt3mLRQZeLY9606	intact-crc:5BBF80C8111703AA|rigid:osyT+kXn2LROWDw5US5nL9twBHY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBU6	uniprotkb:P54136	intact:EBI-25402072	intact:EBI-355482|uniprotkb:Q9BWA1|uniprotkb:B2RBS9|uniprotkb:Q53GY4|ensembl:ENSP00000231572.3|intact:EBI-28985219	psi-mi:a0a0h3lbu6_mycte(display_long)|uniprotkb:ERDMAN_2717(locus name)	psi-mi:syrc_human(display_long)|uniprotkb:RARS1(gene name)|psi-mi:RARS1(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:RARS(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402078|imex:IM-27663-54	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052892|interpro:IPR029471|interpro:IPR003615(HNH nuclease)|mint:A0A0H3LBU6	"efo:""Orphanet:438114""|ensembl:ENSG00000113643.9(gene)|ensembl:ENST00000231572.8(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0004814""(arginine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006418""(tRNA aminoacylation for protein translation)|go:""GO:0006420""(arginyl-tRNA aminoacylation)|go:""GO:0016020""(membrane)|go:""GO:0017101""(aminoacyl-tRNA synthetase multienzyme complex)|go:""GO:0034618""(arginine binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:P54136|rcsb pdb:4Q2T|rcsb pdb:4Q2X|rcsb pdb:4Q2Y|rcsb pdb:4R3Z|rcsb pdb:4ZAJ|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-9856649|refseq:NP_002878.2|panther:PTHR11956(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:TwEFubiRQBJZQJeZgeiegVcK8cs652616	rogid:oM9gWF1NucjgVjBFm4DcjmnQNCE9606	intact-crc:5BBF80C8111703AA|rigid:osyT+kXn2LROWDw5US5nL9twBHY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBU6	uniprotkb:Q14257	intact:EBI-25402072	intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|uniprotkb:F8WCY5|ensembl:ENSP00000378349.3	psi-mi:a0a0h3lbu6_mycte(display_long)|uniprotkb:ERDMAN_2717(locus name)	psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402078|imex:IM-27663-54	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052892|interpro:IPR029471|interpro:IPR003615(HNH nuclease)|mint:A0A0H3LBU6	"refseq:NP_002893.1|refseq:NP_001258766.1|ensembl:ENSG00000117906.14(gene)|ensembl:ENST00000394885.8(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|panther:PTHR10827(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/25	rogid:TwEFubiRQBJZQJeZgeiegVcK8cs652616	rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606	intact-crc:5BBF80C8111703AA|rigid:osyT+kXn2LROWDw5US5nL9twBHY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LIS0	uniprotkb:P22307	intact:EBI-25402095	intact:EBI-1050999|uniprotkb:Q15432|uniprotkb:Q16622|uniprotkb:Q99430|uniprotkb:Q5VVZ1|uniprotkb:D3DQ37|uniprotkb:Q6NXF4|uniprotkb:B4DHP6|uniprotkb:A6NM69|uniprotkb:B4DGJ9|uniprotkb:C9JC79|uniprotkb:E1B6W5|uniprotkb:F2Z3J1|ensembl:ENSP00000360569.3	psi-mi:a0a0h3lis0_mycte(display_long)|uniprotkb:ERDMAN_2741(locus name)	psi-mi:scp2_human(display_long)|uniprotkb:Propanoyl-CoA C-acyltransferase(gene name synonym)|uniprotkb:Sterol carrier protein X(gene name synonym)|uniprotkb:SCP-chi(gene name synonym)|uniprotkb:SCPX(gene name synonym)|uniprotkb:SCP2(gene name)|psi-mi:SCP2(display_short)|uniprotkb:Acetyl-CoA C-myristoyltransferase(gene name synonym)|uniprotkb:Non-specific lipid-transfer protein(gene name synonym)|uniprotkb:SCP-2/3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:SCP-2/thiolase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402102|imex:IM-27663-72	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003900858.1|interpro:IPR005268(Conserved hypothetical protein CHP00725)|interpro:IPR041164|mint:A0A0H3LIS0	"efo:""Orphanet:163684""|ensembl:ENSG00000116171.19(gene)|ensembl:ENST00000371514.8(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0003988""(acetyl-CoA C-acyltransferase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0006694""(steroid biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0006701""(progesterone biosynthetic process)|go:""GO:0008206""(bile acid metabolic process)|go:""GO:0008526""(phosphatidylinositol transfer activity)|go:""GO:0015485""(cholesterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0016020""(membrane)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032385""(positive regulation of intracellular cholesterol transport)|go:""GO:0032959""(inositol trisphosphate biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033540""(fatty acid beta-oxidation using acyl-CoA oxidase)|go:""GO:0033814""(propanoyl-CoA C-acyltransferase activity)|go:""GO:0036042""(long-chain fatty acyl-CoA binding)|go:""GO:0036109""(alpha-linolenic acid metabolic process)|go:""GO:0045940""(positive regulation of steroid metabolic process)|go:""GO:0050632""(propionyl-CoA C2-trimethyltridecanoyltransferase activity)|go:""GO:0050633""(acetyl-CoA C-myristoyltransferase activity)|go:""GO:0070538""(oleic acid binding)|go:""GO:0071071""(regulation of phospholipid biosynthetic process)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0120019""(phosphatidylcholine transfer activity)|go:""GO:0120020""(cholesterol transfer activity)|go:""GO:1901373""(lipid hydroperoxide transport)|interpro:IPR003033(Sterol-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR036527|interpro:IPR055140|mint:P22307|rcsb pdb:1QND|rcsb pdb:2C0L|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-9033241|reactome:R-HSA-9033500|refseq:NP_001007099.1|refseq:NP_001007100.1|refseq:NP_001007101.1|refseq:NP_001007251.1|refseq:NP_001180528.1|refseq:NP_001180546.1|refseq:NP_002970.2|refseq:XP_016857535.1|panther:PTHR24314(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:+tiPH+/MfBoeuUk38896lFFVtbw652616	rogid:Vwnu7RuD/2qhcH55Fl9v2TMErtc9606	intact-crc:BCE4EB792AB4BCB5|rigid:nnSJA9poyMEuMF25W6JUduwIjrY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LIS0	uniprotkb:Q15018	intact:EBI-25402095	intact:EBI-1056583|uniprotkb:Q96H11|uniprotkb:B4DKR2|ensembl:ENSP00000298492.5|intact:EBI-28981592	psi-mi:a0a0h3lis0_mycte(display_long)|uniprotkb:ERDMAN_2741(locus name)	psi-mi:abrx2_human(display_long)|uniprotkb:ABRAXAS2(gene name)|psi-mi:ABRAXAS2(display_short)|uniprotkb:ABRO1(gene name synonym)|uniprotkb:Abraxas brother protein 1(gene name synonym)|uniprotkb:FAM175B(gene name synonym)|uniprotkb:KIAA0157(gene name synonym)|uniprotkb:Protein FAM175B(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402102|imex:IM-27663-72	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003900858.1|interpro:IPR005268(Conserved hypothetical protein CHP00725)|interpro:IPR041164|mint:A0A0H3LIS0	"refseq:NP_115558.3|ensembl:ENSG00000165660.8(gene)|ensembl:ENST00000298492.6(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000922""(spindle pole)|go:""GO:0002931""(response to ischemia)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0007059""(chromosome segregation)|go:""GO:0008017""(microtubule binding)|go:""GO:0008608""(attachment of spindle microtubules to kinetochore)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0051301""(cell division)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0070552""(BRISC complex)|go:""GO:0090307""(mitotic spindle assembly)|interpro:IPR023238|interpro:IPR023240|interpro:IPR037518|mint:Q15018|rcsb pdb:6H3C|rcsb pdb:6R8F|reactome:R-HSA-5689901|panther:PTHR31728(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:+tiPH+/MfBoeuUk38896lFFVtbw652616	rogid:fYZdQpH09qcBBUV1IKV2wsRk4m89606	intact-crc:BCE4EB792AB4BCB5|rigid:nnSJA9poyMEuMF25W6JUduwIjrY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LHQ1	uniprotkb:Q8IWR0	intact:EBI-25402112	intact:EBI-724271|uniprotkb:Q9NPE9|uniprotkb:D3DUG5|ensembl:ENSP00000347999.4|ensembl:ENSP00000379773.2	psi-mi:a0a0h3lhq1_mycte(display_long)|uniprotkb:ERDMAN_3320(locus name)	psi-mi:z3h7a_human(display_long)|uniprotkb:ZC3H7A(gene name)|psi-mi:ZC3H7A(display_short)|uniprotkb:ZC3H7(gene name synonym)|uniprotkb:ZC3HDC7(gene name synonym)|uniprotkb:HSPC055(orf name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402118|imex:IM-27663-56	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003415932.1|interpro:IPR025637|mint:A0A0H3LHQ1	"refseq:NP_054872.2|refseq:XP_006720940.1|refseq:XP_011520765.1|ensembl:ENSG00000122299.12(gene)|ensembl:ENST00000355758.9(transcript)|ensembl:ENST00000396516.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0035196""(miRNA processing)|go:""GO:0035198""(miRNA binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036236|interpro:IPR036855|interpro:IPR039691|mint:Q8IWR0|rcsb pdb:2D9M|panther:PTHR14928(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:PvLVzB4L7oIg1rc/n1iiziSleOs652616	rogid:9jUCQwl3/lLQ979tdqWlZ0Zszns9606	intact-crc:EECEAD652F52B395|rigid:+zcdWgji9hIzE/XgRIIvStw9M8k	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LHQ1	uniprotkb:P55209	intact:EBI-25402112	intact:EBI-356392|uniprotkb:B3KNT8|ensembl:ENSP00000376947.3|ensembl:ENSP00000477538.1|uniprotkb:B3KV44|intact:EBI-21355522	psi-mi:a0a0h3lhq1_mycte(display_long)|uniprotkb:ERDMAN_3320(locus name)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402118|imex:IM-27663-56	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003415932.1|interpro:IPR025637|mint:A0A0H3LHQ1	"refseq:NP_004528.1|refseq:NP_631946.1|ensembl:ENSG00000187109.15(gene)|ensembl:ENST00000393263.7(transcript)|ensembl:ENST00000618691.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0042393""(histone binding)|go:""GO:0042470""(melanosome)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0140713""(histone chaperone activity)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|interpro:IPR002164(""Nucleosome assembly protein (NAP)"")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|rcsb pdb:7UN3|rcsb pdb:7UN6|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|panther:PTHR11875(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:PvLVzB4L7oIg1rc/n1iiziSleOs652616	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	intact-crc:EECEAD652F52B395|rigid:+zcdWgji9hIzE/XgRIIvStw9M8k	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LHQ1	uniprotkb:Q15365	intact:EBI-25402112	intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556.5	psi-mi:a0a0h3lhq1_mycte(display_long)|uniprotkb:ERDMAN_3320(locus name)	psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402118|imex:IM-27663-56	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003415932.1|interpro:IPR025637|mint:A0A0H3LHQ1	"refseq:NP_006187.2|ensembl:ENSG00000169564.7(gene)|ensembl:ENST00000303577.7(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0039694""(viral RNA genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098847""(sequence-specific single stranded DNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-38136N|ensembl:ENSP00000305556.5|panther:PTHR10288(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:PvLVzB4L7oIg1rc/n1iiziSleOs652616	rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606	intact-crc:EECEAD652F52B395|rigid:+zcdWgji9hIzE/XgRIIvStw9M8k	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LHQ1	uniprotkb:Q14005	intact:EBI-25402112	intact:EBI-2831580|uniprotkb:A8MU65|uniprotkb:B9EGR6|uniprotkb:Q6ZMQ7|uniprotkb:Q9UP18|uniprotkb:A6NM20|uniprotkb:Q16435|uniprotkb:Q6VVE6|uniprotkb:B5TY35|uniprotkb:H3BVH5|ensembl:ENSP00000508085.1|intact:EBI-28973443	psi-mi:a0a0h3lhq1_mycte(display_long)|uniprotkb:ERDMAN_3320(locus name)	psi-mi:il16_human(display_long)|uniprotkb:IL16(gene name)|psi-mi:IL16(display_short)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402118|imex:IM-27663-56	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003415932.1|interpro:IPR025637|mint:A0A0H3LHQ1	"refseq:XP_011519822.1|refseq:NP_001165599.1|refseq:NP_004504.3|refseq:NP_757366.2|refseq:XP_005254403.1|refseq:XP_016877630.1|refseq:XP_016877631.1|ensembl:ENSG00000172349.19(gene)|ensembl:ENST00000683961.1(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006955""(immune response)|go:""GO:0016607""(nuclear speck)|go:""GO:0030595""(leukocyte chemotaxis)|go:""GO:0032730""(positive regulation of interleukin-1 alpha production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050930""(induction of positive chemotaxis)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0090543""(Flemming body)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|interpro:IPR055287|mint:Q14005|rcsb pdb:1I16|rcsb pdb:1X6D|rcsb pdb:5FB8|reactome:R-HSA-449836|dip:DIP-6006N|panther:PTHR48396(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:PvLVzB4L7oIg1rc/n1iiziSleOs652616	rogid:3kcSA6a4uuNCcII2VNJRIVUGY+89606	intact-crc:EECEAD652F52B395|rigid:+zcdWgji9hIzE/XgRIIvStw9M8k	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LHQ1	uniprotkb:Q14847	intact:EBI-25402112	intact:EBI-742828|uniprotkb:Q96ED2|uniprotkb:Q96IG0|uniprotkb:B4DGQ0|ensembl:ENSP00000325240.6	psi-mi:a0a0h3lhq1_mycte(display_long)|uniprotkb:ERDMAN_3320(locus name)	psi-mi:lasp1_human(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short)|uniprotkb:MLN50(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402118|imex:IM-27663-56	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_003415932.1|interpro:IPR025637|mint:A0A0H3LHQ1	"refseq:NP_006139.1|refseq:NP_001258537.1|ensembl:ENSG00000002834.19(gene)|ensembl:ENST00000318008.11(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0015075""(monoatomic ion transmembrane transporter activity)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051015""(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|interpro:IPR051759|mint:Q14847|rcsb pdb:3I35|panther:PTHR46218(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/24	rogid:PvLVzB4L7oIg1rc/n1iiziSleOs652616	rogid:Oa+FdJXeQhahYTqVrHYk6yBrUWI9606	intact-crc:EECEAD652F52B395|rigid:+zcdWgji9hIzE/XgRIIvStw9M8k	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LIL2	uniprotkb:Q86TI2	intact:EBI-25402151	intact:EBI-7475352|uniprotkb:Q8N2J7|uniprotkb:Q1ZZB8|uniprotkb:O75273|uniprotkb:Q8WXD8|uniprotkb:Q9BVR3|uniprotkb:Q6AI37|uniprotkb:Q8N3F5|uniprotkb:Q96NT8|uniprotkb:Q6UAL0|intact:MINT-4535936|uniprotkb:O75868|uniprotkb:Q6ZMT2|uniprotkb:Q6ZNJ5|ensembl:ENSP00000469603.1|ensembl:ENSP00000515514.1	psi-mi:a0a0h3lil2_mycte(display_long)|uniprotkb:ERDMAN_3583(locus name)	psi-mi:dpp9_human(display_long)|uniprotkb:DPP9(gene name)|psi-mi:DPP9(display_short)|uniprotkb:DPRP2(gene name synonym)|uniprotkb:Dipeptidyl peptidase IV-related protein 2(gene name synonym)|uniprotkb:Dipeptidyl peptidase IX(gene name synonym)|uniprotkb:Dipeptidyl peptidase-like protein 9(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402157|imex:IM-27663-74	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050922|interpro:IPR027381|interpro:IPR004474(Cell envelope-related transcriptional attenuator)|mint:A0A0H3LIL2	"efo:""Orphanet:2032""|ensembl:ENSG00000142002.19(gene)|ensembl:ENST00000593973.2(transcript)|ensembl:ENST00000598800.5(transcript)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006508""(proteolysis)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008239""(dipeptidyl-peptidase activity)|go:""GO:0031252""(cell leading edge)|go:""GO:0042802""(identical protein binding)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0070269""(pyroptotic inflammatory response)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002469(Peptidase S9B, dipeptidylpeptidase IV N-terminal)|interpro:IPR029058|interpro:IPR045785|interpro:IPR050278|mint:Q86TI2|rcsb pdb:6EOQ|rcsb pdb:6QZV|rcsb pdb:6EOR|rcsb pdb:6X6A|rcsb pdb:6X6C|rcsb pdb:7A3F|rcsb pdb:7JKQ|rcsb pdb:7JN7|rcsb pdb:7SVL|rcsb pdb:7SVN|rcsb pdb:7ZXS|refseq:NP_631898.3|refseq:XP_005259730.1|refseq:XP_011526710.1|refseq:XP_011526712.1|panther:PTHR11731(orthology-group)"	-	-	comment:mint|function:Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/01/24	rogid:SJboGZtFkqJe0gb7AqIuEA/ZTow652616	rogid:m3rJ6BPsdQqnesPiTY9vclr5hE49606	intact-crc:AC6499F1D86DFD05|rigid:HKm0IFpVLtTDc/EWq/vU+qtrMnQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LFD6	uniprotkb:P51610	intact:EBI-25402163	intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|ensembl:ENSP00000309555.7|intact:EBI-14324845|intact:EBI-12980473	psi-mi:a0a0h3lfd6_mycte(display_long)|uniprotkb:ERDMAN_4015(locus name)	psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402169|imex:IM-27663-58	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|interpro:IPR043504|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|mint:A0A0H3LFD6"	"ensembl:ENSG00000172534.14(gene)|ensembl:ENST00000310441.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0019046""(release from viral latency)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0044545""(NSL complex)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0050821""(protein stabilization)|go:""GO:0071339""(MLL1 complex)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-9772755|refseq:NP_005325.2|refseq:XP_006724879.1|efo:""Orphanet:369962""|efo:""Orphanet:777""|dip:DIP-32955N|panther:PTHR46003(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:ttTOSC4/+t/sY9Pm2IsAwjUHhzg652616	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	intact-crc:15E7F9A65AC0A870|rigid:0+7zdYRYVxxuVog0xA7UKdrZU1Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LFG6	uniprotkb:Q8N726	intact:EBI-25402175	intact:EBI-625922|uniprotkb:Q13195|uniprotkb:Q13399|uniprotkb:Q16360|uniprotkb:Q7KZR9|uniprotkb:D3DRK2|ensembl:ENSP00000432664.2|ensembl:ENSP00000462950.1	psi-mi:a0a0h3lfg6_mycte(display_long)|uniprotkb:ERDMAN_4058(locus name)	psi-mi:arf_human(display_long)|uniprotkb:p14ARF(gene name synonym)|uniprotkb:CDKN2A(gene name)|psi-mi:CDKN2A(display_short)|uniprotkb:CDKN2(gene name synonym)|uniprotkb:MLM(gene name synonym)|uniprotkb:Alternative reading frame(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402182|imex:IM-27663-60	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:WP_003419812.1|interpro:IPR026954|interpro:IPR038232|mint:A0A0H3LFG6"	"ensembl:ENSG00000147889.18(gene)|ensembl:ENST00000530628.2(transcript)|ensembl:ENST00000579755.2(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0002039""(p53 binding)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006364""(rRNA processing)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016925""(protein sumoylation)|go:""GO:0019789""(SUMO transferase activity)|go:""GO:0030575""(nuclear body organization)|refseq:NP_478102.2|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031648""(protein destabilization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033088""(negative regulation of immature T cell proliferation in thymus)|go:""GO:0033235""(positive regulation of protein sumoylation)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043517""(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0048103""(somatic stem cell division)|go:""GO:0050821""(protein stabilization)|go:""GO:0051444""(negative regulation of ubiquitin-protein transferase activity)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051882""(mitochondrial depolarization)|go:""GO:0055105""(ubiquitin-protein transferase inhibitor activity)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0090398""(cellular senescence)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1901798""(positive regulation of signal transduction by p53 class mediator)|go:""GO:1902570""(protein localization to nucleolus)|go:""GO:1903051""(negative regulation of proteolysis involved in protein catabolic process)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|go:""GO:1904667""(negative regulation of ubiquitin protein ligase activity)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990948""(ubiquitin ligase inhibitor activity)|go:""GO:2000059""(negative regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000435""(negative regulation of protein neddylation)|interpro:IPR010868(Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal)|mint:Q8N726|reactome:R-HSA-111471|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-6804757|reactome:R-HSA-69541|reactome:R-HSA-8941858|reactome:R-HSA-9645722|reactome:R-HSA-9646303|reactome:R-HSA-9646304|reactome:R-HSA-9759194|dip:DIP-24171N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/27	rogid:otYp8Zhu7tLjfXPnNultwBITScw652616	rogid:zdbvJmkrI/zJFL+Enq5jTM1Csdw9606	intact-crc:0DCEA9202B6863FD|rigid:gm4hgNMGsQse/PuNrZUqUX4wXsk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LMP0	uniprotkb:P50991	intact:EBI-25402198	intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958.3	psi-mi:a0a0h3lmp0_mycte(display_long)|uniprotkb:ERDMAN_4076(locus name)	psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 4(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402208|imex:IM-27663-62	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004069""(""L-aspartate:2-oxoglutarate aminotransferase activity"")|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:WP_003899653.1|mint:A0A0H3LMP0"	"refseq:NP_006421.2|refseq:NP_001243650.1|ensembl:ENSG00000115484.15(gene)|ensembl:ENST00000394440.8(transcript)|go:""GO:0002199""(zona pellucida receptor complex)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0042470""(melanosome)|go:""GO:0042995""(cell projection)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044297""(cell body)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090666""(scaRNA localization to Cajal body)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904851""(positive regulation of establishment of protein localization to telomere)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR053374|interpro:IPR054827|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7TUB|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I9Q|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHD|rcsb pdb:8SHE|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32971N|panther:PTHR11353(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA652616	rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606	intact-crc:2F47D9ADE05F89C2|rigid:rCMBcJ6ISWtKIagdzCfgSQ4tFLI	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LMP0	uniprotkb:P48643	intact:EBI-25402198	intact:EBI-355710|uniprotkb:A8JZY8|uniprotkb:A8K2X8|uniprotkb:B4DYD8|ensembl:ENSP00000280326.4	psi-mi:a0a0h3lmp0_mycte(display_long)|uniprotkb:ERDMAN_4076(locus name)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 5(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402208|imex:IM-27663-62	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004069""(""L-aspartate:2-oxoglutarate aminotransferase activity"")|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:WP_003899653.1|mint:A0A0H3LMP0"	"efo:""Orphanet:139578""|ensembl:ENSG00000150753.12(gene)|ensembl:ENST00000280326.9(transcript)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0009615""(response to virus)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031681""(G-protein beta-subunit binding)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044297""(cell body)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904851""(positive regulation of establishment of protein localization to telomere)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012718(T-complex protein 1, epsilon subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR053374|interpro:IPR054827|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7TUB|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8AJM|rcsb pdb:8AJO|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHD|rcsb pdb:8SHE|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|refseq:NP_001293084.1|refseq:NP_036205.1|dip:DIP-31181N|panther:PTHR11353(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA652616	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:2F47D9ADE05F89C2|rigid:rCMBcJ6ISWtKIagdzCfgSQ4tFLI	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LMP0	uniprotkb:P50990	intact:EBI-25402198	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788.4|ensembl:ENSP00000517017.1	psi-mi:a0a0h3lmp0_mycte(display_long)|uniprotkb:ERDMAN_4076(locus name)	psi-mi:tcpq_human(display_long)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402208|imex:IM-27663-62	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004069""(""L-aspartate:2-oxoglutarate aminotransferase activity"")|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:WP_003899653.1|mint:A0A0H3LMP0"	"panther:PTHR11353(orthology-group)|refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|rcsb pdb:8SHE|ensembl:ENSG00000156261.13(gene)|ensembl:ENSG00000291533.1(gene)|ensembl:ENST00000286788.9(transcript)|ensembl:ENST00000707884.1(transcript)|go:""GO:0002199""(zona pellucida receptor complex)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005874""(microtubule)|go:""GO:0005929""(cilium)|go:""GO:0006457""(protein folding)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0016887""(ATP hydrolysis activity)|rcsb pdb:8SHD|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044297""(cell body)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045296""(cadherin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7TUB|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6798695|reactome:R-HSA-6814122|dip:DIP-38124N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA652616	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:2F47D9ADE05F89C2|rigid:rCMBcJ6ISWtKIagdzCfgSQ4tFLI	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LMP0	uniprotkb:P78371	intact:EBI-25402198	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300.6	psi-mi:a0a0h3lmp0_mycte(display_long)|uniprotkb:ERDMAN_4076(locus name)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402208|imex:IM-27663-62	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004069""(""L-aspartate:2-oxoglutarate aminotransferase activity"")|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:WP_003899653.1|mint:A0A0H3LMP0"	"panther:PTHR11353(orthology-group)|refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226.13(gene)|ensembl:ENST00000299300.11(transcript)|go:""GO:0002199""(zona pellucida receptor complex)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044297""(cell body)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090666""(scaRNA localization to Cajal body)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR053374|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7TUB|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHD|rcsb pdb:8SHE|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA652616	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:2F47D9ADE05F89C2|rigid:rCMBcJ6ISWtKIagdzCfgSQ4tFLI	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LMP0	uniprotkb:P49368	intact:EBI-25402198	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688.3	psi-mi:a0a0h3lmp0_mycte(display_long)|uniprotkb:ERDMAN_4076(locus name)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402208|imex:IM-27663-62	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004069""(""L-aspartate:2-oxoglutarate aminotransferase activity"")|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:WP_003899653.1|mint:A0A0H3LMP0"	"refseq:NP_001008800.1|panther:PTHR11353(orthology-group)|refseq:NP_005989.3|ensembl:ENSG00000163468.15(gene)|ensembl:ENST00000295688.8(transcript)|go:""GO:0002199""(zona pellucida receptor complex)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044297""(cell body)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904851""(positive regulation of establishment of protein localization to telomere)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR053374|interpro:IPR054827|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7TUB|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I6J|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHD|rcsb pdb:8SHE|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA652616	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:2F47D9ADE05F89C2|rigid:rCMBcJ6ISWtKIagdzCfgSQ4tFLI	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LMP0	uniprotkb:Q99832	intact:EBI-25402198	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091.5	psi-mi:a0a0h3lmp0_mycte(display_long)|uniprotkb:ERDMAN_4076(locus name)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 7(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402208|imex:IM-27663-62	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004069""(""L-aspartate:2-oxoglutarate aminotransferase activity"")|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:WP_003899653.1|mint:A0A0H3LMP0"	"panther:PTHR11353(orthology-group)|dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624.17(gene)|ensembl:ENST00000258091.10(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0042802""(identical protein binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044297""(cell body)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904851""(positive regulation of establishment of protein localization to telomere)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR053374|interpro:IPR054827|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7TUB|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHD|rcsb pdb:8SHE|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA652616	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:2F47D9ADE05F89C2|rigid:rCMBcJ6ISWtKIagdzCfgSQ4tFLI	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LMP0	uniprotkb:P40227	intact:EBI-25402198	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|intact:EBI-5912031|uniprotkb:A6NCD2|ensembl:ENSP00000275603.4|intact:EBI-26518976	psi-mi:a0a0h3lmp0_mycte(display_long)|uniprotkb:ERDMAN_4076(locus name)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 6A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402208|imex:IM-27663-62	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004069""(""L-aspartate:2-oxoglutarate aminotransferase activity"")|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:WP_003899653.1|mint:A0A0H3LMP0"	"panther:PTHR11353(orthology-group)|refseq:NP_001753.1|refseq:NP_001009186.1|ensembl:ENSG00000146731.11(gene)|ensembl:ENST00000275603.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071987""(WD40-repeat domain binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904851""(positive regulation of establishment of protein localization to telomere)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR053374|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7TUB|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHD|rcsb pdb:8SHE|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|dip:DIP-33558N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA652616	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:2F47D9ADE05F89C2|rigid:rCMBcJ6ISWtKIagdzCfgSQ4tFLI	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBW4	uniprotkb:P01111	intact:EBI-25402228	intact:EBI-721993|uniprotkb:Q14971|uniprotkb:Q15104|uniprotkb:Q15282|ensembl:ENSP00000358548.4	psi-mi:a0a0h3lbw4_mycte(display_long)|uniprotkb:TB8.4(gene name)|psi-mi:TB8.4(display_short)|uniprotkb:ERDMAN_1317(locus name)	psi-mi:rasn_human(display_long)|uniprotkb:Transforming protein N-Ras(gene name synonym)|uniprotkb:NRAS(gene name)|psi-mi:NRAS(display_short)|uniprotkb:HRAS1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402237|imex:IM-27663-64	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0020037""(heme binding)|refseq:WP_003406169.1|interpro:IPR032407|interpro:IPR016572(Uncharacterised conserved protein UCP010611)|mint:A0A0H3LBW4"	"efo:""Orphanet:146""|efo:""Orphanet:2612""|efo:""Orphanet:268114""|efo:""Orphanet:389""|efo:""Orphanet:626""|efo:""Orphanet:648""|efo:""Orphanet:86834""|ensembl:ENSG00000213281.5(gene)|ensembl:ENST00000369535.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0019003""(GDP binding)|go:""GO:0044877""(protein-containing complex binding)|rcsb pdb:6MPP|go:""GO:0045445""(myoblast differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01111|rcsb pdb:2N9C|rcsb pdb:3CON|rcsb pdb:5UHV|rcsb pdb:6E6H|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6WGH|rcsb pdb:6ZIO|rcsb pdb:6ZIR|rcsb pdb:6ZIZ|rcsb pdb:7F68|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7PB2|rcsb pdb:8TBI|rcsb pdb:8VM2|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5658442|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9753510|reactome:R-HSA-9753512|refseq:NP_002515.1|dip:DIP-1058N|panther:PTHR24070(orthology-group)|ensembl:ENSP00000358548.4"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:1+GXTs4GNP41DIMGsE0zpUUw89U652616	rogid:Et90BD+t6LnYThbW6ShQge1GRK89606	intact-crc:2177CD181D2C19CC|rigid:sFb5qX57t0/XL23gxcTUq+y3fjk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBW4	uniprotkb:Q32MZ4	intact:EBI-25402228	intact:EBI-1369100|uniprotkb:O75766|uniprotkb:O75799|uniprotkb:Q32MZ5|uniprotkb:Q53T49|uniprotkb:Q6PKG2|uniprotkb:E9PGZ2|uniprotkb:Q9Y607|ensembl:ENSP00000375857.4|intact:EBI-28987401	psi-mi:a0a0h3lbw4_mycte(display_long)|uniprotkb:TB8.4(gene name)|psi-mi:TB8.4(display_short)|uniprotkb:ERDMAN_1317(locus name)	psi-mi:lrrf1_human(display_long)|uniprotkb:LRRFIP1(gene name)|psi-mi:LRRFIP1(display_short)|uniprotkb:GCF2(gene name synonym)|uniprotkb:TRIP(gene name synonym)|uniprotkb:TAR RNA-interacting protein(gene name synonym)|uniprotkb:GC-binding factor 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402237|imex:IM-27663-64	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0020037""(heme binding)|refseq:WP_003406169.1|interpro:IPR032407|interpro:IPR016572(Uncharacterised conserved protein UCP010611)|mint:A0A0H3LBW4"	"refseq:NP_001131024.1|refseq:NP_001131025.1|refseq:NP_004726.2|refseq:NP_001131022.1|ensembl:ENSG00000124831.20(gene)|ensembl:ENST00000392000.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|interpro:IPR019139|mint:Q32MZ4|rcsb pdb:4H22|reactome:R-HSA-1839117|reactome:R-HSA-3134973|reactome:R-HSA-5655302|panther:PTHR19212(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:1+GXTs4GNP41DIMGsE0zpUUw89U652616	rogid:GRBGUu5k+BNhFDb4Z2B2XkQ0mcQ9606	intact-crc:2177CD181D2C19CC|rigid:sFb5qX57t0/XL23gxcTUq+y3fjk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBW4	uniprotkb:Q15907	intact:EBI-25402228	intact:EBI-722234|uniprotkb:Q2YDT2|uniprotkb:Q8NI07|uniprotkb:B2R7I4|uniprotkb:D6W671|uniprotkb:A5YM50|uniprotkb:Q5U0I1|uniprotkb:Q6FHR0|uniprotkb:Q6FI42|uniprotkb:B4DMK0|ensembl:ENSP00000333547.5	psi-mi:a0a0h3lbw4_mycte(display_long)|uniprotkb:TB8.4(gene name)|psi-mi:TB8.4(display_short)|uniprotkb:ERDMAN_1317(locus name)	psi-mi:rb11b_human(display_long)|uniprotkb:GTP-binding protein YPT3(gene name synonym)|uniprotkb:RAB11B(gene name)|psi-mi:RAB11B(display_short)|uniprotkb:YPT3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402237|imex:IM-27663-64	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0020037""(heme binding)|refseq:WP_003406169.1|interpro:IPR032407|interpro:IPR016572(Uncharacterised conserved protein UCP010611)|mint:A0A0H3LBW4"	"refseq:NP_004209.2|ensembl:ENSG00000185236.12(gene)|ensembl:ENST00000328024.11(transcript)|go:""GO:0001881""(receptor recycling)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0019003""(GDP binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031489""(myosin V binding)|go:""GO:0032402""(melanosome transport)|go:""GO:0032456""(endocytic recycling)|go:""GO:0033572""(transferrin transport)|go:""GO:0035773""(insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0044070""(regulation of monoatomic anion transport)|go:""GO:0045054""(constitutive secretory pathway)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071468""(cellular response to acidic pH)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:2000008""(regulation of protein localization to cell surface)|go:""GO:2001135""(regulation of endocytic recycling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050209|mint:Q15907|rcsb pdb:2F9L|rcsb pdb:2F9M|rcsb pdb:4OJK|reactome:R-HSA-8854214|reactome:R-HSA-8873719|dip:DIP-50898N|panther:PTHR47979(orthology-group)"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:1+GXTs4GNP41DIMGsE0zpUUw89U652616	rogid:+fsu7NPmd5fgoe0TE67IcISlscA9606	intact-crc:2177CD181D2C19CC|rigid:sFb5qX57t0/XL23gxcTUq+y3fjk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:A0A0H3LBW4	uniprotkb:P20339	intact:EBI-25402228	intact:EBI-399437|uniprotkb:B4DJA5|intact:EBI-1048179|uniprotkb:Q6FI44|ensembl:ENSP00000273047.4	psi-mi:a0a0h3lbw4_mycte(display_long)|uniprotkb:TB8.4(gene name)|psi-mi:TB8.4(display_short)|uniprotkb:ERDMAN_1317(locus name)	psi-mi:rab5a_human(display_long)|uniprotkb:RAB5A(gene name)|psi-mi:RAB5A(display_short)|uniprotkb:RAB5(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402237|imex:IM-27663-64	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0020037""(heme binding)|refseq:WP_003406169.1|interpro:IPR032407|interpro:IPR016572(Uncharacterised conserved protein UCP010611)|mint:A0A0H3LBW4"	"refseq:NP_004153.2|panther:PTHR24073(orthology-group)|refseq:NP_001278977.1|ensembl:ENSG00000144566.11(gene)|ensembl:ENST00000273047.9(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006909""(phagocytosis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0010008""(endosome membrane)|go:""GO:0012505""(endomembrane system)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0019003""(GDP binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032009""(early phagosome)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0036477""(somatodendritic compartment)|go:""GO:0042470""(melanosome)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043195""(terminal bouton)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043679""(axon terminus)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045121""(membrane raft)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0051036""(regulation of endosome size)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098559""(cytoplasmic side of early endosome membrane)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P20339|rcsb pdb:1N6H|rcsb pdb:1N6I|rcsb pdb:1N6K|rcsb pdb:1N6L|rcsb pdb:1N6N|rcsb pdb:1N6O|rcsb pdb:1N6P|rcsb pdb:1N6R|rcsb pdb:1R2Q|rcsb pdb:1TU3|rcsb pdb:1TU4|rcsb pdb:3MJH|rcsb pdb:4Q9U|rcsb pdb:7BL1|reactome:R-HSA-1660499|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9636383|reactome:R-HSA-9820960|reactome:R-HSA-983231|dip:DIP-380N"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/03/26	rogid:1+GXTs4GNP41DIMGsE0zpUUw89U652616	rogid:SgowwV7QSVCvfsqSDE+6CHmPmKA9606	intact-crc:2177CD181D2C19CC|rigid:sFb5qX57t0/XL23gxcTUq+y3fjk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q16881	uniprotkb:A0A0H3LFI2	intact:EBI-716617|uniprotkb:Q6FI31|uniprotkb:Q6VB40|uniprotkb:Q6VB41|uniprotkb:Q6VB42|uniprotkb:Q6VBP2|uniprotkb:Q6VBP3|uniprotkb:Q6VBP4|uniprotkb:Q6VBP5|uniprotkb:Q6VBP9|uniprotkb:Q6VBQ0|uniprotkb:Q6YNQ1|uniprotkb:Q8WVC8|uniprotkb:Q99475|uniprotkb:Q9UES8|uniprotkb:Q76P53|uniprotkb:Q7LA96|uniprotkb:Q9UH79|uniprotkb:B7Z1F4|uniprotkb:B7Z3Y8|uniprotkb:B7Z904|uniprotkb:E9PMY9|uniprotkb:F5H780|ensembl:ENSP00000434516.1	intact:EBI-25402257	psi-mi:trxr1_human(display_long)|uniprotkb:KDRF(gene name synonym)|uniprotkb:Thioredoxin reductase TR1(gene name synonym)|uniprotkb:KM-102-derived reductase-like factor(gene name synonym)|uniprotkb:GRIM12(gene name synonym)|uniprotkb:TXNRD1(gene name)|psi-mi:TXNRD1(display_short)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 12 protein(gene name synonym)|uniprotkb:Peroxidase TXNRD1(gene name synonym)	psi-mi:a0a0h3lfi2_mycte(display_long)|uniprotkb:trxA(gene name)|psi-mi:trxA(display_short)|uniprotkb:ERDMAN_1637(locus name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25402267|imex:IM-27663-66	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001087240.1|refseq:NP_003321.3|refseq:NP_877393.1|refseq:NP_877419.1|refseq:NP_877420.1|refseq:NP_001248374.1|refseq:NP_001248375.1|ensembl:ENSG00000198431.18(gene)|ensembl:ENST00000525566.6(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001707""(mesoderm formation)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0050137""(NADPH peroxidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071949""(FAD binding)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|interpro:IPR036249|interpro:IPR046952|mint:Q16881|rcsb pdb:2CFY|rcsb pdb:2J3N|rcsb pdb:2ZZ0|rcsb pdb:2ZZB|rcsb pdb:2ZZC|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:7X1R|reactome:R-HSA-1989781|reactome:R-HSA-2408550|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5263617|reactome:R-HSA-5336415|reactome:R-HSA-5628897|reactome:R-HSA-9818027|panther:PTHR48105(orthology-group)"	"go:""GO:0016491""(oxidoreductase activity)|go:""GO:0045454""(cell redox homeostasis)|interpro:IPR036249|interpro:IPR013766(Thioredoxin domain)|refseq:WP_003900345.1|mint:A0A0H3LFI2"	-	-	-	figure legend:ST4 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2024/11/14	rogid:0CrcaHgTDl4AIU4V2zXt3u9Pet89606	rogid:78JHZRa5D9HyCwp5P+mCrG7X+VQ652616	intact-crc:209631940759AF45|rigid:UyX7s3wshw/c2iv2bpgHORjyxJM	false	-	strep tag:c-c	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q9Y4P1	uniprotkb:A0A0H3LAC5	intact:EBI-712014|uniprotkb:Q6ZUV8|uniprotkb:Q8WYM9|uniprotkb:Q96K07|uniprotkb:Q96K96|uniprotkb:Q96SZ1|uniprotkb:Q9Y2F2|uniprotkb:Q53NU4|uniprotkb:B7WNK2|ensembl:ENSP00000384259.3	intact:EBI-25401874	psi-mi:atg4b_human(display_long)|uniprotkb:Autophagy-related protein 4 homolog B(gene name synonym)|uniprotkb:Autophagy-related cysteine endopeptidase 1(gene name synonym)|uniprotkb:AUT-like 1 cysteine endopeptidase(gene name synonym)|uniprotkb:ATG4B(gene name)|psi-mi:ATG4B(display_short)|uniprotkb:APG4B(gene name synonym)|uniprotkb:AUTL1(gene name synonym)|uniprotkb:KIAA0943(gene name synonym)	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401868|imex:IM-27663-37	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037457.3|refseq:NP_847896.1|ensembl:ENSG00000168397.17(gene)|ensembl:ENST00000404914.8(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0000423""(mitophagy)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0006914""(autophagy)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0015031""(protein transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0016237""(microautophagy)|go:""GO:0016485""(protein processing)|go:""GO:0019786""(protein-phosphatidylethanolamide deconjugating activity)|go:""GO:0031173""(otolith mineralization completed early in development)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034497""(protein localization to phagophore assembly site)|go:""GO:0034727""(piecemeal microautophagy of the nucleus)|go:""GO:0035973""(aggrephagy)|go:""GO:0051697""(protein delipidation)|go:""GO:0097110""(scaffold protein binding)|interpro:IPR005078(Peptidase C54)|interpro:IPR038765|interpro:IPR046792|interpro:IPR046793|mint:Q9Y4P1|rcsb pdb:2CY7|rcsb pdb:2D1I|rcsb pdb:2Z0D|rcsb pdb:2Z0E|rcsb pdb:2ZZP|rcsb pdb:5LXH|rcsb pdb:5LXI|reactome:R-HSA-1632852|panther:PTHR22624(orthology-group)"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	-	-	-	figure legend:SF1E|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/01/17	2024/11/14	rogid:xSDsMshJik2bdLQ06b0kErCLxyM9606	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	intact-crc:BB220642774AE1D8|rigid:8psA4106mcCcOxc3IPDMlsj+/CY	false	flag tag:?-?	strep tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q9Y4B6	uniprotkb:A0A0H3LAC5	intact:EBI-1996353|uniprotkb:Q2YD74|uniprotkb:Q8TBD9|uniprotkb:Q9HCA1|uniprotkb:Q9UG37|ensembl:ENSP00000393183.2|ensembl:ENSP00000506880.1|intact:EBI-2559078|intact:EBI-28988191	intact:EBI-25401874	psi-mi:dcaf1_human(display_long)|uniprotkb:DCAF1(gene name)|psi-mi:DCAF1(display_short)|uniprotkb:HIV-1 Vpr-binding protein(gene name synonym)|uniprotkb:KIAA0800(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:VPRBP(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym)	psi-mi:a0a0h3lac5_mycte(display_long)|uniprotkb:ERDMAN_2289(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401883|imex:IM-27663-39	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:1990244""(histone H2AT120 kinase activity)|refseq:NP_001165375.1|refseq:NP_055518.1|refseq:XP_011532575.1|refseq:XP_011532576.1|refseq:XP_011532577.1|refseq:XP_011532578.1|refseq:XP_011532579.1|ensembl:ENSG00000145041.17(gene)|ensembl:ENST00000423656.5(transcript)|ensembl:ENST00000684031.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0033151""(""V(D)J recombination"")|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035212""(cell competition in a multicellular organism)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|rcsb pdb:4P7I|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|mint:Q9Y4B6|rcsb pdb:3WA0|rcsb pdb:4CC9|rcsb pdb:4PXW|rcsb pdb:4Z8L|rcsb pdb:5AJA|rcsb pdb:5JK7|rcsb pdb:6N45|rcsb pdb:6ZUE|rcsb pdb:6ZX9|rcsb pdb:7OKQ|rcsb pdb:7SSE|rcsb pdb:7UFV|rcsb pdb:7V7B|rcsb pdb:7V7C|rcsb pdb:8F8E|rcsb pdb:8OG5|rcsb pdb:8OG6|rcsb pdb:8OG7|rcsb pdb:8OG8|rcsb pdb:8OG9|rcsb pdb:8OGA|rcsb pdb:8OGB|rcsb pdb:8OGC|rcsb pdb:8OO5|rcsb pdb:8OOD|rcsb pdb:9BHR|rcsb pdb:9BHS|rcsb pdb:9C1Q|reactome:R-HSA-983168|refseq:XP_005276810.1|refseq:XP_005276812.1|panther:PTHR13129(orthology-group)|refseq:XP_016863035.1|refseq:XP_016863036.1|refseq:XP_016863037.1|refseq:XP_016863038.1|refseq:XP_016863039.1|dip:DIP-47048N"	"go:""GO:0005829""(cytosol)|go:""GO:0016627""(oxidoreductase activity, acting on the CH-CH group of donors)|go:""GO:0070967""(coenzyme F420 binding)|interpro:IPR052019|refseq:WP_003899157.1|interpro:IPR019920|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|mint:A0A0H3LAC5"	-	-	-	figure legend:suppl. fig. 1 F|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/01/17	2025/03/17	rogid:qs3qG0MM135EE/DjC1S/gCLRFhc9606	rogid:cryKHrkqTwMBH+syGMASAtIIRdo652616	intact-crc:A6515F42028FD2E8|rigid:84iGV484eh6pgOuCNzRGzItsWoI	false	flag tag:?-?	strep tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P22681	uniprotkb:A0A0H3L6J6	intact:EBI-518228|uniprotkb:A3KMP8|ensembl:ENSP00000264033.3	intact:EBI-25401182	psi-mi:cbl_human(display_long)|uniprotkb:Signal transduction protein CBL(gene name synonym)|uniprotkb:Proto-oncogene c-Cbl(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)|uniprotkb:RING finger protein 55(gene name synonym)|uniprotkb:CBL(gene name)|psi-mi:CBL(display_short)|uniprotkb:CBL2(gene name synonym)|uniprotkb:RNF55(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401782|imex:IM-27663-35	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:363972""|efo:""Orphanet:648""|efo:""Orphanet:86834""|efo:""Orphanet:98850""|ensembl:ENSG00000110395.8(gene)|ensembl:ENST00000264033.6(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0008584""(male gonad development)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0014823""(response to activity)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016600""(flotillin complex)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0030426""(growth cone)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0032487""(regulation of Rap protein signal transduction)|go:""GO:0033574""(response to testosterone)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036312""(phosphatidylinositol 3-kinase regulatory subunit binding)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042594""(response to starvation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043303""(mast cell degranulation)|go:""GO:0045121""(membrane raft)|go:""GO:0045296""(cadherin binding)|go:""GO:0045471""(response to ethanol)|go:""GO:0045742""(positive regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070086""(ubiquitin-dependent endocytosis)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:2000583""(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR009060(UBA-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018957|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|rcsb pdb:6O03|interpro:IPR036860|mint:P22681|rcsb pdb:1B47|rcsb pdb:1FBV|rcsb pdb:1YVH|rcsb pdb:2CBL|rcsb pdb:2JUJ|rcsb pdb:2K4D|rcsb pdb:2OO9|rcsb pdb:2Y1M|rcsb pdb:2Y1N|rcsb pdb:3BUM|rcsb pdb:3BUN|rcsb pdb:3BUO|rcsb pdb:3BUW|rcsb pdb:3BUX|rcsb pdb:3OB1|rcsb pdb:3OB2|rcsb pdb:3PLF|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4GPL|rcsb pdb:5HKW|rcsb pdb:5HKX|rcsb pdb:5HKY|rcsb pdb:5HKZ|rcsb pdb:5HL0|rcsb pdb:5J3X|rcsb pdb:5O76|rcsb pdb:6O02|rcsb pdb:6XAR|rcsb pdb:7SIY|reactome:R-HSA-1059683|reactome:R-HSA-1236382|reactome:R-HSA-1295596|reactome:R-HSA-1433559|reactome:R-HSA-182971|reactome:R-HSA-2173789|reactome:R-HSA-5637810|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6807004|reactome:R-HSA-8849469|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-912631|reactome:R-HSA-9680350|reactome:R-HSA-9706369|reactome:R-HSA-9706377|refseq:NP_005179.2|dip:DIP-189N|panther:PTHR23007(orthology-group)|ensembl:ENSP00000264033.3"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	-	-	-	figure legend:SF4|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/17	2025/02/06	rogid:WPXFRmBKHEANKUlN/OYsuyAe9a09606	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	intact-crc:3468293EDC15E80E|rigid:FMNn3QMA8Q4iHRdfdOjjE+HBETc	false	flag tag:c-c	strep tag:c-c	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:P22681	uniprotkb:A0A0H3L6J6	intact:EBI-518228|uniprotkb:A3KMP8|ensembl:ENSP00000264033.3	intact:EBI-25401182	psi-mi:cbl_human(display_long)|uniprotkb:Signal transduction protein CBL(gene name synonym)|uniprotkb:Proto-oncogene c-Cbl(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)|uniprotkb:RING finger protein 55(gene name synonym)|uniprotkb:CBL(gene name)|psi-mi:CBL(display_short)|uniprotkb:CBL2(gene name synonym)|uniprotkb:RNF55(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)	psi-mi:a0a0h3l6j6_mycte(display_long)|uniprotkb:lpqN(gene name)|psi-mi:lpqN(display_short)|uniprotkb:ERDMAN_0641(locus name)	"psi-mi:""MI:0096""(pull down)"	Penn et al. (2018)	imex:IM-27663|pubmed:30118682	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")|taxid:652616(""Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25401860|imex:IM-27663-19	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:363972""|efo:""Orphanet:648""|efo:""Orphanet:86834""|efo:""Orphanet:98850""|ensembl:ENSG00000110395.8(gene)|ensembl:ENST00000264033.6(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0008584""(male gonad development)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0014823""(response to activity)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016600""(flotillin complex)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0030426""(growth cone)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0032487""(regulation of Rap protein signal transduction)|go:""GO:0033574""(response to testosterone)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036312""(phosphatidylinositol 3-kinase regulatory subunit binding)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042594""(response to starvation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043303""(mast cell degranulation)|go:""GO:0045121""(membrane raft)|go:""GO:0045296""(cadherin binding)|go:""GO:0045471""(response to ethanol)|go:""GO:0045742""(positive regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070086""(ubiquitin-dependent endocytosis)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:2000583""(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR009060(UBA-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR018957|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|rcsb pdb:6O03|interpro:IPR036860|mint:P22681|rcsb pdb:1B47|rcsb pdb:1FBV|rcsb pdb:1YVH|rcsb pdb:2CBL|rcsb pdb:2JUJ|rcsb pdb:2K4D|rcsb pdb:2OO9|rcsb pdb:2Y1M|rcsb pdb:2Y1N|rcsb pdb:3BUM|rcsb pdb:3BUN|rcsb pdb:3BUO|rcsb pdb:3BUW|rcsb pdb:3BUX|rcsb pdb:3OB1|rcsb pdb:3OB2|rcsb pdb:3PLF|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4GPL|rcsb pdb:5HKW|rcsb pdb:5HKX|rcsb pdb:5HKY|rcsb pdb:5HKZ|rcsb pdb:5HL0|rcsb pdb:5J3X|rcsb pdb:5O76|rcsb pdb:6O02|rcsb pdb:6XAR|rcsb pdb:7SIY|reactome:R-HSA-1059683|reactome:R-HSA-1236382|reactome:R-HSA-1295596|reactome:R-HSA-1433559|reactome:R-HSA-182971|reactome:R-HSA-2173789|reactome:R-HSA-5637810|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6807004|reactome:R-HSA-8849469|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-912631|reactome:R-HSA-9680350|reactome:R-HSA-9706369|reactome:R-HSA-9706377|refseq:NP_005179.2|dip:DIP-189N|panther:PTHR23007(orthology-group)|ensembl:ENSP00000264033.3"	refseq:WP_003403052.1|interpro:IPR019674|mint:A0A0H3L6J6	-	-	-	figure legend:F4F|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2020/01/17	2025/02/06	rogid:WPXFRmBKHEANKUlN/OYsuyAe9a09606	rogid:QmotiHd89RrI1RCUDHLN4Is7BoQ652616	intact-crc:53AACD6FA1755F09|rigid:FMNn3QMA8Q4iHRdfdOjjE+HBETc	false	-	strep tag:c-c	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:O84008	uniprotkb:Q86UP2	intact:EBI-22302424	intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3|ensembl:ENSP00000378725.3|ensembl:ENSP00000432149.1	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001072989.1|refseq:NP_004977.2|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|ensembl:ENSG00000126777.18(gene)|ensembl:ENST00000395314.8(transcript)|ensembl:ENST00000459737.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019894""(kinesin binding)|go:""GO:0045296""(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:XP_011535053.1|refseq:XP_011535055.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N|panther:PTHR18864(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:O95819	intact:EBI-22302424	intact:EBI-2511133|intact:EBI-28985706|uniprotkb:O75172|uniprotkb:Q9NST7|uniprotkb:E7ESS2|ensembl:ENSP00000314363.6	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:m4k4_human(display_long)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_663719.2|refseq:NP_001229488.1|refseq:NP_004825.3|refseq:NP_663720.1|ensembl:ENSG00000071054.17(gene)|ensembl:ENST00000347699.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001953""(negative regulation of cell-matrix adhesion)|go:""GO:0004111""(creatine kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008017""(microtubule binding)|go:""GO:0008349""(MAP kinase kinase kinase kinase activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032014""(positive regulation of ARF protein signal transduction)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046328""(regulation of JNK cascade)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120183""(positive regulation of focal adhesion disassembly)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR051700|mint:O95819|rcsb pdb:4OBO|rcsb pdb:4OBP|rcsb pdb:4OBQ|rcsb pdb:4RVT|rcsb pdb:4U3Y|rcsb pdb:4U3Z|rcsb pdb:4U40|rcsb pdb:4U41|rcsb pdb:4U42|rcsb pdb:4U43|rcsb pdb:4U44|rcsb pdb:4U45|rcsb pdb:4ZK5|rcsb pdb:4ZP5|rcsb pdb:5DI1|rcsb pdb:5J95|rcsb pdb:5W5Q|reactome:R-HSA-2559580|panther:PTHR48015(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:wEXGp6vM4HhwldyeQJKvEdilMpQ9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9UL54	intact:EBI-22302424	intact:EBI-352832|uniprotkb:O94957|uniprotkb:Q6UW73|uniprotkb:Q7LC09|uniprotkb:Q9NSW2|uniprotkb:B2RN35|uniprotkb:A5PKY1|uniprotkb:A7MCZ2|uniprotkb:B7ZM88|ensembl:ENSP00000310094.4	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:taok2_human(display_long)|uniprotkb:TAOK2(gene name)|psi-mi:TAOK2(display_short)|uniprotkb:KIAA0881(gene name synonym)|uniprotkb:MAP3K17(gene name synonym)|uniprotkb:PSK(gene name synonym)|uniprotkb:PSK1(gene name synonym)|uniprotkb:UNQ2971/PRO7431(orf name)|uniprotkb:Prostate-derived sterile 20-like kinase 1(gene name synonym)|uniprotkb:Thousand and one amino acid protein kinase 2(gene name synonym)|uniprotkb:Kinase from chicken homolog C(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_004774.1|refseq:NP_057235.2|refseq:NP_001238972.1|ensembl:ENSG00000149930.18(gene)|ensembl:ENST00000308893.9(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007409""(axonogenesis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016477""(cell migration)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030424""(axon)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031434""(mitogen-activated protein kinase kinase binding)|go:""GO:0031954""(positive regulation of protein autophosphorylation)|go:""GO:0032147""(activation of protein kinase activity)|go:""GO:0032874""(positive regulation of stress-activated MAPK cascade)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038191""(neuropilin binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043235""(receptor complex)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044294""(dendritic growth cone)|go:""GO:0044295""(axonal growth cone)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:0150019""(basal dendrite morphogenesis)|go:""GO:0150020""(basal dendrite arborization)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR051234|mint:Q9UL54|panther:PTHR47167(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:aA9reWZMb8l6Ziy+jyX5bbTD6vE9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:O14617	intact:EBI-22302424	intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055.4	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"efo:""Orphanet:664511""|dip:DIP-46793N|ensembl:ENSG00000065000.20(gene)|ensembl:ENST00000345016.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016182""(synaptic vesicle budding from endosome)|go:""GO:0016183""(synaptic vesicle coating)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0032438""(melanosome organization)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0043195""(terminal bouton)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046907""(intracellular transport)|go:""GO:0048007""(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0048499""(synaptic vesicle membrane organization)|go:""GO:0051138""(positive regulation of NK T cell differentiation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140916""(zinc ion import into lysosome)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|refseq:NP_001248755.1|refseq:NP_003929.4|efo:""Orphanet:1000""|efo:""Orphanet:54""|panther:PTHR22781(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:P20585	intact:EBI-22302424	intact:EBI-1164205|uniprotkb:Q6PJT5|uniprotkb:Q86UQ6|uniprotkb:Q92867|uniprotkb:A6NMM6|uniprotkb:A1L482|uniprotkb:A1L480|ensembl:ENSP00000265081.6	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:msh3_human(display_long)|uniprotkb:Divergent upstream protein(gene name synonym)|uniprotkb:Mismatch repair protein 1(gene name synonym)|uniprotkb:MSH3(gene name)|psi-mi:MSH3(display_short)|uniprotkb:DUC1(gene name synonym)|uniprotkb:DUG(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"panther:PTHR11361(orthology-group)|dip:DIP-35127N|ensembl:ENSG00000113318.11(gene)|ensembl:ENST00000265081.7(transcript)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0006298""(mismatch repair)|go:""GO:0006312""(mitotic recombination)|go:""GO:0016020""(membrane)|go:""GO:0016447""(somatic recombination of immunoglobulin gene segments)|go:""GO:0019899""(enzyme binding)|go:""GO:0030983""(mismatched DNA binding)|go:""GO:0032302""(MutSbeta complex)|go:""GO:0043570""(maintenance of DNA repeat elements)|go:""GO:0045910""(negative regulation of DNA recombination)|go:""GO:0051096""(positive regulation of helicase activity)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|interpro:IPR045076|mint:P20585|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|rcsb pdb:8OLX|rcsb pdb:8OM5|rcsb pdb:8OM9|rcsb pdb:8OMA|rcsb pdb:8OMO|rcsb pdb:8OMQ|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|refseq:NP_002430.3|efo:""Orphanet:480536"""	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:6nxGZyJMsk7NfSFhDftKiT/omSE9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q05397	intact:EBI-22302424	intact:EBI-702142|uniprotkb:Q14291|uniprotkb:Q9UD85|intact:EBI-11047590|uniprotkb:B4E2N6|uniprotkb:F5H4S4|ensembl:ENSP00000429474.1|ensembl:ENSP00000429911.1|uniprotkb:J3QT16|uniprotkb:Q8IYN9	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:fak1_human(display_long)|uniprotkb:PTK2(gene name)|psi-mi:PTK2(display_short)|uniprotkb:FAK(gene name synonym)|uniprotkb:FAK1(gene name synonym)|uniprotkb:pp125FAK(gene name synonym)|uniprotkb:Protein-tyrosine kinase 2(gene name synonym)|uniprotkb:Focal adhesion kinase-related nonkinase(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 71(gene name synonym)|uniprotkb:p125FAK(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_722560.1|refseq:NP_001186578.1|ensembl:ENSG00000169398.20(gene)|ensembl:ENST00000521059.5(transcript)|ensembl:ENST00000522684.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001725""(stress fiber)|go:""GO:0001890""(placenta development)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003779""(actin binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007172""(signal complex assembly)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0010632""(regulation of epithelial cell migration)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0016477""(cell migration)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035995""(detection of muscle stretch)|go:""GO:0036064""(ciliary basal body)|go:""GO:0038007""(netrin-activated signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043087""(regulation of GTPase activity)|go:""GO:0043197""(dendritic spine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048870""(cell motility)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060396""(growth hormone receptor signaling pathway)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0120041""(positive regulation of macrophage proliferation)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900024""(regulation of substrate adhesion-dependent cell spreading)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR029071|interpro:IPR035963|interpro:IPR036137|interpro:IPR041390|interpro:IPR041784|interpro:IPR049385|mint:Q05397|rcsb pdb:1K04|rcsb pdb:1K05|rcsb pdb:1MP8|rcsb pdb:1OW6|rcsb pdb:1OW7|rcsb pdb:1OW8|rcsb pdb:2ETM|rcsb pdb:2IJM|rcsb pdb:3B71|rcsb pdb:3BZ3|rcsb pdb:3PXK|rcsb pdb:3S9O|rcsb pdb:4EBV|rcsb pdb:4EBW|rcsb pdb:4GU6|rcsb pdb:4GU9|rcsb pdb:4I4E|rcsb pdb:4I4F|rcsb pdb:4K8A|rcsb pdb:4K9Y|rcsb pdb:4KAB|rcsb pdb:4KAO|rcsb pdb:4NY0|rcsb pdb:4Q9S|rcsb pdb:6I8Z|rcsb pdb:6LES|rcsb pdb:6PW8|rcsb pdb:6YOJ|rcsb pdb:6YQ1|rcsb pdb:6YR9|rcsb pdb:6YT6|rcsb pdb:6YVS|rcsb pdb:6YVY|rcsb pdb:6YXV|rcsb pdb:7PI4|rcsb pdb:7W7Z|rcsb pdb:7W8B|rcsb pdb:7W8I|rcsb pdb:7W9U|reactome:R-HSA-111465|reactome:R-HSA-2029482|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-8874081|reactome:R-HSA-9009391|reactome:R-HSA-9634638|reactome:R-HSA-9664422|reactome:R-HSA-9860927|refseq:XP_016869162.1|panther:PTHR24418(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:8q4JfaNYtMdXVLU77d1EtSP0lVg9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:O95782	intact:EBI-22302424	intact:EBI-353552|uniprotkb:Q96CI7|uniprotkb:Q96PP6|uniprotkb:Q96PP7|uniprotkb:Q9H070|ensembl:ENSP00000351926.4|intact:EBI-28973302	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ap2a1_human(display_long)|uniprotkb:AP2A1(gene name)|psi-mi:AP2A1(display_short)|uniprotkb:ADTAA(gene name synonym)|uniprotkb:CLAPA1(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_055018.2|refseq:NP_570603.2|ensembl:ENSG00000196961.13(gene)|ensembl:ENST00000359032.10(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0006897""(endocytosis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030130""(clathrin coat of trans-Golgi network vesicle)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0032433""(filopodium tip)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098843""(postsynaptic endocytic zone)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900126""(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR050840|mint:O95782|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|dip:DIP-33164N|panther:PTHR22780(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:egkaIAhvIi1FqNr+8KEFeJaYZcc9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q10567	intact:EBI-22302424	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:O94973	intact:EBI-22302424	intact:EBI-1642835|uniprotkb:O75403|uniprotkb:Q96SI8|uniprotkb:Q53ET1|ensembl:ENSP00000413234.3	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ap2a2_human(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001229766.1|refseq:NP_036437.1|ensembl:ENSG00000183020.15(gene)|ensembl:ENST00000448903.7(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008289""(lipid binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR050840|mint:O94973|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-6798695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|panther:PTHR22780(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:sda1msOBssgmBiU3ZfSyk3z7/jc9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q8TCJ2	intact:EBI-22302424	intact:EBI-2256290|ensembl:ENSP00000295770.2|uniprotkb:Q96JZ4|uniprotkb:Q96KY7	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:stt3b_human(display_long)|uniprotkb:STT3B(gene name)|psi-mi:STT3B(display_short)|uniprotkb:SIMP(gene name synonym)|uniprotkb:Source of immunodominant MHC-associated peptides homolog(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000163527.11(gene)|ensembl:ENST00000295770.4(transcript)|go:""GO:0004579""(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0006516""(glycoprotein catabolic process)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036503""(ERAD pathway)|go:""GO:0043686""(co-translational protein modification)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0046872""(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|interpro:IPR048307|interpro:IPR048999|mint:Q8TCJ2|rcsb pdb:6S7T|refseq:NP_849193.1|efo:""Orphanet:370924""|panther:PTHR13872(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:4F+9LbIZTFRoczuphd1jzuhnFDo9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q12797	intact:EBI-22302424	intact:EBI-2967294|uniprotkb:B4E2K4|uniprotkb:F5H667|uniprotkb:Q9NRI0|uniprotkb:Q9Y4J0|uniprotkb:Q9H2C4|uniprotkb:A6NDF4|uniprotkb:Q9NRI1|uniprotkb:A6NHI2|uniprotkb:B4DIC9|uniprotkb:B7ZM95|uniprotkb:E5RGP5|uniprotkb:Q6NXR7|uniprotkb:Q8TB28|uniprotkb:Q9H291|intact:EBI-8994140|uniprotkb:A0A0A0MSK8|ensembl:ENSP00000368767.4	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:asph_human(display_long)|uniprotkb:ASPH(gene name)|psi-mi:ASPH(display_short)|uniprotkb:Aspartate beta-hydroxylase(gene name synonym)|uniprotkb:Peptide-aspartate beta-dioxygenase(gene name synonym)|uniprotkb:BAH(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000198363.18(gene)|ensembl:ENST00000379454.9(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005513""(detection of calcium ion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006936""(muscle contraction)|go:""GO:0007389""(pattern specification process)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0009055""(electron transfer activity)|go:""GO:0010524""(positive regulation of calcium ion transport into cytosol)|go:""GO:0010649""(regulation of cell communication by electrical coupling)|go:""GO:0010880""(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0014701""(junctional sarcoplasmic reticulum membrane)|go:""GO:0031585""(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032237""(activation of store-operated calcium channel activity)|go:""GO:0032541""(cortical endoplasmic reticulum)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0033018""(sarcoplasmic reticulum lumen)|go:""GO:0033198""(response to ATP)|go:""GO:0034704""(calcium channel complex)|go:""GO:0035108""(limb morphogenesis)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060021""(roof of mouth development)|go:""GO:0060314""(regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0060316""(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0060325""(face morphogenesis)|go:""GO:0062101""(peptidyl-aspartic acid 3-dioxygenase activity)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:1901879""(regulation of protein depolymerization)|interpro:IPR007803(Aspartyl/Asparaginyl beta-hydroxylase)|interpro:IPR007943(Aspartyl beta-hydroxylase, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027443|interpro:IPR039038|mint:Q12797|rcsb pdb:5APA|rcsb pdb:5JQY|rcsb pdb:5JTC|rcsb pdb:5JZ6|rcsb pdb:5JZ8|rcsb pdb:5JZA|rcsb pdb:5JZU|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6QA5|rcsb pdb:6RK9|rcsb pdb:6YYU|rcsb pdb:6YYV|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|rcsb pdb:7YB8|rcsb pdb:7YB9|rcsb pdb:7YBA|rcsb pdb:7YBB|rcsb pdb:7YBC|reactome:R-HSA-2672351|reactome:R-HSA-5578775|reactome:R-HSA-9629569|refseq:NP_001158222.1|refseq:NP_001158223.1|refseq:NP_001158225.1|refseq:NP_001158227.1|refseq:NP_001158228.1|refseq:NP_004309.2|refseq:NP_064549.1|refseq:NP_115855.1|refseq:NP_115856.1|refseq:NP_115857.1|efo:""Orphanet:412022""|panther:PTHR12366(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:8Sv1CuwqdVCK6/PF6kL0hkX3/tw9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9UER7	intact:EBI-22302424	intact:EBI-77321|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7|ensembl:ENSP00000266000.6|ensembl:ENSP00000363668.5|ensembl:ENSP00000372539.4|ensembl:ENSP00000372681.4|ensembl:ENSP00000382014.3|ensembl:ENSP00000382281.3|ensembl:ENSP00000394108.2|ensembl:ENSP00000404376.2|ensembl:ENSP00000404623.1|ensembl:ENSP00000410772.2	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001135441.1|refseq:NP_001241646.1|refseq:NP_001341.1|panther:PTHR12766(orthology-group)|dip:DIP-27628N|ensembl:ENSP00000266000.6|ensembl:ENSP00000363668.5|ensembl:ENSP00000372539.4|ensembl:ENSP00000372681.4|ensembl:ENSP00000382014.3|ensembl:ENSP00000382281.3|ensembl:ENST00000414083.6|ensembl:ENSP00000396876.2|ensembl:ENSP00000404623.1|ensembl:ENSP00000404376.2|ensembl:ENSP00000394108.2|ensembl:ENSP00000410772.2|ensembl:ENST00000612868.4|ensembl:ENSP00000479172.1|ensembl:ENST00000612888.2|ensembl:ENSP00000483394.1|ensembl:ENST00000613912.3|ensembl:ENSP00000477633.1|ensembl:ENST00000616312.1|ensembl:ENSP00000483517.1|ensembl:ENST00000617660.4|ensembl:ENSP00000480448.1|ensembl:ENST00000619421.1|ensembl:ENSP00000478810.1|ensembl:ENST00000620164.4|ensembl:ENSP00000482399.1|ensembl:ENST00000622655.1|ensembl:ENSP00000484830.1|ensembl:ENSG00000204209.13(gene)|ensembl:ENSG00000206206.11(gene)|ensembl:ENSG00000206279.10(gene)|ensembl:ENSG00000227046.8(gene)|ensembl:ENSG00000231617.8(gene)|ensembl:ENST00000266000.10(transcript)|ensembl:ENST00000374542.10(transcript)|ensembl:ENST00000383062.8(transcript)|ensembl:ENST00000383194.8(transcript)|ensembl:ENST00000399060.7(transcript)|ensembl:ENST00000399344.7(transcript)|ensembl:ENST00000433482.5(transcript)|ensembl:ENST00000436311.6(transcript)|ensembl:ENST00000445009.6(transcript)|ensembl:ENST00000455860.6(transcript)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002039""(p53 binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007254""(JNK cascade)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016604""(nuclear body)|go:""GO:0016605""(PML body)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031396""(regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0036480""(neuron intrinsic apoptotic signaling pathway in response to oxidative stress)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071276""(cellular response to cadmium ion)|go:""GO:0071280""(cellular response to copper ion)|go:""GO:0072738""(cellular response to diamide)|go:""GO:0140416""(transcription regulator inhibitor activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1903936""(cellular response to sodium arsenite)|interpro:IPR031333|interpro:IPR038298|interpro:IPR046378|interpro:IPR046426|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q8TAF3	intact:EBI-22302424	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491.5	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"dip:DIP-50841N|efo:""Orphanet:401800""|ensembl:ENSG00000114742.14(gene)|ensembl:ENST00000302313.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043588""(skin development)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:1902525""(regulation of protein monoubiquitination)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|interpro:IPR051246|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|refseq:NP_065890.1|panther:PTHR19862(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9HDC5	intact:EBI-22302424	intact:EBI-465137|uniprotkb:B2RTZ0|ensembl:ENSP00000344488.4	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_065698.1|refseq:XP_005251331.1|refseq:XP_005251332.1|refseq:NP_001304759.1|panther:PTHR23085(orthology-group)|ensembl:ENSG00000104369.5(gene)|ensembl:ENST00000342232.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007517""(muscle organ development)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0014701""(junctional sarcoplasmic reticulum membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0030018""(Z disc)|go:""GO:0030314""(junctional membrane complex)|go:""GO:0060314""(regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0060402""(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|rcsb pdb:7RW4"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9BXF6	intact:EBI-22302424	intact:EBI-1387068|uniprotkb:O94939|uniprotkb:Q9P0M1|ensembl:ENSP00000258098.6	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:rfip5_human(display_long)|uniprotkb:RAB11FIP5(gene name)|psi-mi:RAB11FIP5(display_short)|uniprotkb:GAF1(gene name synonym)|uniprotkb:KIAA0857(gene name synonym)|uniprotkb:RIP11(gene name synonym)|uniprotkb:Rab11-interacting protein Rip11(gene name synonym)|uniprotkb:Gamma-SNAP-associated factor 1(gene name synonym)|uniprotkb:Phosphoprotein pp75(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_056285.1|ensembl:ENSG00000135631.17(gene)|ensembl:ENST00000258098.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0030141""(secretory granule)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035773""(insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070164""(negative regulation of adiponectin secretion)|go:""GO:0071468""(cellular response to acidic pH)|go:""GO:2000008""(regulation of protein localization to cell surface)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR019018|interpro:IPR035892|interpro:IPR037245|interpro:IPR037789|mint:Q9BXF6|panther:PTHR15746(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:X3eYUlRpL+nSmU4gfUEA5RntseY9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q8TAA9	intact:EBI-22302424	intact:EBI-682393|uniprotkb:Q86WG8|uniprotkb:Q8N559|uniprotkb:Q5T1D3|uniprotkb:Q5T1D4|ensembl:ENSP00000310800.3|ensembl:ENSP00000347672.2|ensembl:ENSP00000358522.1	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:vang1_human(display_long)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Strabismus 2(gene name synonym)|uniprotkb:Loop-tail protein 2 homolog(gene name synonym)|uniprotkb:VANGL1(gene name)|psi-mi:VANGL1(display_short)|uniprotkb:STB2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"efo:""Orphanet:3027""|ensembl:ENSG00000173218.15(gene)|ensembl:ENST00000310260.7(transcript)|ensembl:ENST00000355485.7(transcript)|ensembl:ENST00000369509.1(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0043473""(pigmentation)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0120197""(mucociliary clearance)|interpro:IPR009539(Strabismus)|mint:Q8TAA9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001165882.1|refseq:NP_001165883.1|refseq:NP_620409.1|panther:PTHR20886(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:TRLqwMf+W5eZcgW8gT5S1zM9VzU9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9ULK5	intact:EBI-22302424	intact:EBI-1054279|uniprotkb:Q5T212|uniprotkb:D3DVE9|ensembl:ENSP00000357040.2	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:vang2_human(display_long)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Strabismus 1(gene name synonym)|uniprotkb:Loop-tail protein 1 homolog(gene name synonym)|uniprotkb:VANGL2(gene name)|psi-mi:VANGL2(display_short)|uniprotkb:KIAA1215(gene name synonym)|uniprotkb:STB1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"efo:""Orphanet:563609""|efo:""Orphanet:563612""|ensembl:ENSG00000162738.8(gene)|ensembl:ENST00000368061.3(transcript)|go:""GO:0001736""(establishment of planar polarity)|go:""GO:0001843""(neural tube closure)|go:""GO:0001947""(heart looping)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0035787""(cell migration involved in kidney development)|go:""GO:0036514""(dopaminergic neuron axon guidance)|go:""GO:0036515""(serotonergic neuron axon guidance)|go:""GO:0045176""(apical protein localization)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q9ULK5|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7R2M|rcsb pdb:7R2T|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_065068.1|refseq:XP_005245414.1|refseq:XP_011508106.1|panther:PTHR20886(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:x6JAZMeK90S/m6+oSp/W1tN1Cjc9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q8NHP6	intact:EBI-22302424	intact:EBI-2812848|uniprotkb:Q8N3H2|uniprotkb:Q8NA83|ensembl:ENSP00000369860.3	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001170946.1|refseq:NP_689794.1|ensembl:ENSG00000130150.12(gene)|ensembl:ENST00000380492.8(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0044232""(organelle membrane contact site)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|go:""GO:0140042""(lipid droplet formation)|go:""GO:0140284""(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|interpro:IPR053012|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|panther:PTHR46384(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q7L804	intact:EBI-22302424	intact:EBI-1049676|uniprotkb:A6NEI4|uniprotkb:Q9Y2F0|ensembl:ENSP00000347839.3|intact:EBI-28973556|uniprotkb:Q3I768	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:rfip2_human(display_long)|uniprotkb:NRip11(gene name synonym)|uniprotkb:RAB11FIP2(gene name)|psi-mi:RAB11FIP2(display_short)|uniprotkb:KIAA0941(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_055719.1|ensembl:ENSG00000107560.12(gene)|ensembl:ENST00000355624.8(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0006909""(phagocytosis)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035669""(TRAM-dependent toll-like receptor 4 signaling pathway)|go:""GO:0035773""(insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042995""(cell projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR019018|interpro:IPR035892|interpro:IPR037245|interpro:IPR037789|mint:Q7L804|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2K6S|rcsb pdb:3TSO|rcsb pdb:4C4P|rcsb pdb:6S8X|reactome:R-HSA-432040|refseq:NP_001317096.1|dip:DIP-29139N|panther:PTHR15746(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:SM9AVuCsVKsV/VsI6FyQuZyq/xE9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q86Y07	intact:EBI-22302424	intact:EBI-1207615|uniprotkb:Q49AK9|uniprotkb:Q53EU9|uniprotkb:Q86Y08|uniprotkb:Q86Y09|uniprotkb:Q86Y10|uniprotkb:Q86Y11|uniprotkb:Q86Y12|uniprotkb:Q8IXI5|uniprotkb:Q99987|uniprotkb:Q53S39|uniprotkb:Q53S77|uniprotkb:Q53TU1|uniprotkb:B4DKL0|uniprotkb:D6W5D4|uniprotkb:D6W5D6|ensembl:ENSP00000342381.4|ensembl:ENSP00000408002.2	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:vrk2_human(display_long)|uniprotkb:VRK2(gene name)|psi-mi:VRK2(display_short)|uniprotkb:Vaccinia-related kinase 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:XP_011531394.1|refseq:XP_006712153.1|refseq:XP_006712154.1|refseq:XP_006712155.1|refseq:XP_006712156.1|refseq:NP_001123952.1|refseq:NP_001123953.1|refseq:NP_001123954.1|refseq:NP_001123955.1|refseq:NP_006287.2|refseq:NP_001275765.1|refseq:NP_001275766.1|refseq:NP_001275767.1|refseq:NP_001275768.1|ensembl:ENSG00000028116.18(gene)|ensembl:ENST00000340157.9(transcript)|ensembl:ENST00000435505.6(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000659""(regulation of interleukin-1-mediated signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR050235|mint:Q86Y07|rcsb pdb:2V62|rcsb pdb:5UU1|rcsb pdb:6NCG|rcsb pdb:8Q1Z|rcsb pdb:9FET|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:XP_005264597.1|panther:PTHR11909(orthology-group)|refseq:XP_016860347.1|refseq:XP_016860348.1|refseq:XP_016860349.1|refseq:XP_016860350.1|refseq:XP_016860351.1|refseq:XP_016860352.1"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:sDftNP5rKcTUJgpJAcbJsNzag0I9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q96CW1	intact:EBI-22302424	intact:EBI-297683|uniprotkb:A6NE12|uniprotkb:P20172|uniprotkb:P53679|ensembl:ENSP00000292807.5|uniprotkb:D3DNT1	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ap2m1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:AP2M1(gene name)|psi-mi:AP2M1(display_short)|uniprotkb:CLAPM1(gene name synonym)|uniprotkb:KIAA0109(gene name synonym)|uniprotkb:Adaptin-mu2(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:HA2 50 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"efo:""Orphanet:1942""|ensembl:ENSG00000161203.14(gene)|ensembl:ENST00000292807.9(transcript)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0005048""(signal sequence binding)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008289""(lipid binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097494""(regulation of vesicle size)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0098794""(postsynapse)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0098894""(extrinsic component of presynaptic endocytic zone membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900244""(positive regulation of synaptic vesicle endocytosis)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|interpro:IPR050431|mint:Q96CW1|rcsb pdb:1H6E|rcsb pdb:6BNT|rcsb pdb:6URI|reactome:R-HSA-164939|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|refseq:NP_001020376.1|refseq:NP_001298127.1|refseq:NP_004059.2|panther:PTHR10529(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9BXS5	intact:EBI-22302424	intact:EBI-541426|uniprotkb:Q4TTY5|ensembl:ENSP00000291439.2	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ap1m1_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-1 subunit(gene name synonym)|uniprotkb:Mu-adaptin 1(gene name synonym)|uniprotkb:AP-mu chain family member mu1A(gene name synonym)|uniprotkb:Mu1A-adaptin(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit mu-1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1 medium chain 1(gene name synonym)|uniprotkb:AP1M1(gene name)|psi-mi:AP1M1(display_short)|uniprotkb:CLTNM(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_115882.1|refseq:NP_001123996.1|ensembl:ENSG00000072958.9(gene)|ensembl:ENST00000291439.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032438""(melanosome organization)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903232""(melanosome assembly)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR050431|mint:Q9BXS5|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|panther:PTHR10529(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:B6OVovdusOdmvB0D+RIyhRRga2Q9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q8TBX8	intact:EBI-22302424	intact:EBI-1383637|uniprotkb:Q9H6N2|uniprotkb:B2RDL3|uniprotkb:B4DM11|uniprotkb:B4DY44|ensembl:ENSP00000347032.5|ensembl:ENSP00000439878.2	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:pi42c_human(display_long)|uniprotkb:PIP4K2C(gene name)|psi-mi:PIP4K2C(display_short)|uniprotkb:PIP5K2C(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II gamma(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001139730.1|refseq:NP_001139731.1|refseq:NP_079055.3|refseq:NP_001139732.1|ensembl:ENSG00000166908.18(gene)|ensembl:ENST00000354947.10(transcript)|ensembl:ENST00000540759.6(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005776""(autophagosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016308""(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:""GO:0016309""(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902635""(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:""GO:2000786""(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027483|interpro:IPR027484|mint:Q8TBX8|rcsb pdb:2GK9|rcsb pdb:7QIE|rcsb pdb:7QPN|rcsb pdb:8BQ4|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453|panther:PTHR23086(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:vC4KtXa6EcyihfFZdCAb3GmQUhs9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:P49674	intact:EBI-22302424	intact:EBI-749343|ensembl:ENSP00000352929.3|ensembl:ENSP00000380044.1|ensembl:ENSP00000384074.1	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|ensembl:ENSG00000213923.13(gene)|ensembl:ENST00000359867.7(transcript)|ensembl:ENST00000396832.6(transcript)|ensembl:ENST00000403904.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006897""(endocytosis)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030426""(growth cone)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048512""(circadian behavior)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000052""(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050235|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-400253|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|dip:DIP-38050N|panther:PTHR11909(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:evdzz03ba4MFWavN9xRae/Wxwio9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:P78356	intact:EBI-22302424	intact:EBI-947090|uniprotkb:Q5U0E8|uniprotkb:Q8TBP2|ensembl:ENSP00000480776.1|ensembl:ENSP00000482548.1	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	"psi-mi:pi42b_human(display_long)|uniprotkb:PIP4K2B(gene name)|psi-mi:PIP4K2B(display_short)|uniprotkb:""PtdIns(5)P-4-kinase isoform 2-beta""(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-beta(gene name synonym)|uniprotkb:PIP5K2B(gene name synonym)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-beta(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II beta(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_003550.1|ensembl:ENSG00000276293.5(gene)|ensembl:ENSG00000277292.2(gene)|ensembl:ENST00000613180.2(transcript)|ensembl:ENST00000619039.5(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005776""(autophagosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016308""(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:""GO:0016309""(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:1902635""(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:""GO:2000786""(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027483|interpro:IPR027484|mint:P78356|rcsb pdb:1BO1|rcsb pdb:3WZZ|rcsb pdb:3X01|rcsb pdb:3X02|rcsb pdb:3X03|rcsb pdb:3X04|rcsb pdb:3X05|rcsb pdb:3X06|rcsb pdb:3X07|rcsb pdb:3X08|rcsb pdb:3X09|rcsb pdb:3X0A|rcsb pdb:3X0B|rcsb pdb:3X0C|rcsb pdb:6K4G|rcsb pdb:6K4H|rcsb pdb:7EM1|rcsb pdb:7EM2|rcsb pdb:7EM3|rcsb pdb:7EM4|rcsb pdb:7EM5|rcsb pdb:7EM6|rcsb pdb:7EM7|rcsb pdb:7EM8|rcsb pdb:7N80|rcsb pdb:7N81|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453|panther:PTHR23086(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:sKU3t4ChBZODcGl1ZUqfncyNkSo9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:P32121	intact:EBI-22302424	intact:EBI-714559|uniprotkb:Q0Z8D3|uniprotkb:Q2PP19|uniprotkb:Q6ICT3|uniprotkb:Q8N7Y2|uniprotkb:Q9UEQ6|uniprotkb:B7WPL3|uniprotkb:B5B0C0|uniprotkb:D3DTK2|intact:EBI-28974065|uniprotkb:B4DLW0|uniprotkb:H0Y688|ensembl:ENSP00000269260.2	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:arrb2_human(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:ARRB2(gene name)|psi-mi:ARRB2(display_short)|uniprotkb:ARB2(gene name synonym)|uniprotkb:ARR2(gene name synonym)|uniprotkb:Non-visual arrestin-3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_004304.1|refseq:NP_945355.1|refseq:NP_001244259.1|refseq:NP_001244260.1|refseq:NP_001244257.1|refseq:NP_001244258.1|ensembl:ENSG00000141480.18(gene)|ensembl:ENST00000269260.7(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0002029""(desensitization of G protein-coupled receptor signaling pathway)|go:""GO:0002031""(G protein-coupled receptor internalization)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007212""(G protein-coupled dopamine receptor signaling pathway)|go:""GO:0007628""(adult walking behavior)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0015031""(protein transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019899""(enzyme binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031701""(angiotensin receptor binding)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032226""(positive regulation of synaptic transmission, dopaminergic)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|reactome:R-HSA-5674135|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043422""(protein kinase B binding)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0098794""(postsynapse)|go:""GO:0098926""(postsynaptic signal transduction)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000727""(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P32121|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-456926|reactome:R-HSA-5099900|reactome:R-HSA-5635838|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9839389|refseq:NP_001316993.1|dip:DIP-40089N|panther:PTHR11792(orthology-group)|ensembl:ENSP00000269260.2|ensembl:ENST00000346341.6|ensembl:ENSP00000341895.2|ensembl:ENST00000381488.10|ensembl:ENSP00000370898.6|ensembl:ENST00000412477.7|ensembl:ENSP00000403701.3"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:MY34flMH9cdhPtMLGYOQtoQyr2U9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:P48426	intact:EBI-22302424	intact:EBI-3924422|uniprotkb:Q5VUX3|uniprotkb:D3DRV1|uniprotkb:B0YJ66|uniprotkb:P53807|uniprotkb:B4DGX2|ensembl:ENSP00000365757.4	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	"psi-mi:pi42a_human(display_long)|uniprotkb:PIP4K2A(gene name)|psi-mi:PIP4K2A(display_short)|uniprotkb:PIP5K2(gene name synonym)|uniprotkb:PIP5K2A(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-alpha(gene name synonym)|uniprotkb:PIP5KIII(gene name synonym)|uniprotkb:""PtdIns(4)P-5-kinase B isoform""(gene name synonym)|uniprotkb:""PtdIns(4)P-5-kinase C isoform""(gene name synonym)|uniprotkb:""PtdIns(5)P-4-kinase isoform 2-alpha""(gene name synonym)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II alpha(gene name synonym)|uniprotkb:PI5P4KA(gene name synonym)|uniprotkb:Phosphatidylinositol 5-Phosphate 4-Kinase(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000150867.14(gene)|ensembl:ENST00000376573.9(transcript)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005776""(autophagosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016308""(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:""GO:0016309""(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:0090119""(vesicle-mediated cholesterol transport)|go:""GO:1902635""(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:""GO:2000786""(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027483|interpro:IPR027484|mint:P48426|rcsb pdb:2YBX|rcsb pdb:6OSP|rcsb pdb:6UX9|rcsb pdb:6YM3|rcsb pdb:6YM4|rcsb pdb:6YM5|rcsb pdb:7N6Z|rcsb pdb:7N71|rcsb pdb:7N7J|rcsb pdb:7N7K|rcsb pdb:7N7L|rcsb pdb:7N7M|rcsb pdb:7N7N|rcsb pdb:7N7O|rcsb pdb:8C8C|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453|refseq:NP_001316991.1|refseq:NP_005019.2|refseq:XP_016871819.1|refseq:XP_016871820.1|efo:""Orphanet:585936""|panther:PTHR23086(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:Fmsp/H2ucCjs7wyiCgEqe9Y5UT49606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:P68400	intact:EBI-22302424	intact:EBI-347804|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|ensembl:ENSP00000217244.3|ensembl:ENSP00000383076.2|ensembl:ENSP00000495248.1|ensembl:ENSP00000495422.1|ensembl:ENSP00000495902.1|ensembl:ENSP00000495912.1|ensembl:ENSP00000495998.1|ensembl:ENSP00000496569.1|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000101266.19(gene)|ensembl:ENST00000217244.9(transcript)|ensembl:ENST00000400217.7(transcript)|ensembl:ENST00000643660.1(transcript)|ensembl:ENST00000645623.1(transcript)|ensembl:ENST00000646305.1(transcript)|ensembl:ENST00000646561.1(transcript)|ensembl:ENST00000646814.1(transcript)|ensembl:ENST00000647348.1(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005956""(protein kinase CK2 complex)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0007165""(signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016301""(kinase activity)|go:""GO:0016605""(PML body)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048511""(rhythmic process)|go:""GO:0050821""(protein stabilization)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070822""(Sin3-type complex)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0075342""(symbiont-mediated disruption of host cell PML body)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1905337""(positive regulation of aggrephagy)|go:""GO:1905818""(regulation of chromosome separation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000042""(negative regulation of double-strand break repair via homologous recombination)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR045216|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:3PE1|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:4DGL|rcsb pdb:4FBX|rcsb pdb:4GRB|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:5CT0|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5OS7|rcsb pdb:5OS8|rcsb pdb:5OSL|rcsb pdb:5OSP|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5OT5|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OWL|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5ZN2|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|rcsb pdb:6A1C|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|rcsb pdb:6TLR|rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7A4Q|rcsb pdb:7AT5|rcsb pdb:7AY9|rcsb pdb:7AYA|rcsb pdb:7B8H|rcsb pdb:7B8I|rcsb pdb:7BU4|rcsb pdb:7L1X|rcsb pdb:7PSU|rcsb pdb:7QGB|rcsb pdb:7QGC|rcsb pdb:7QGD|rcsb pdb:7QGE|rcsb pdb:7QUX|rcsb pdb:7X4H|rcsb pdb:7Z39|rcsb pdb:7ZWE|rcsb pdb:7ZWG|rcsb pdb:7ZY0|rcsb pdb:7ZY2|rcsb pdb:7ZY5|rcsb pdb:7ZY8|rcsb pdb:7ZYD|rcsb pdb:7ZYK|rcsb pdb:7ZYO|rcsb pdb:7ZYR|rcsb pdb:8AE7|rcsb pdb:8AEC|rcsb pdb:8AEK|rcsb pdb:8AEM|rcsb pdb:8BGC|rcsb pdb:8C5Q|rcsb pdb:8C6L|rcsb pdb:8C6M|rcsb pdb:8C6N|rcsb pdb:8P05|rcsb pdb:8P06|rcsb pdb:8P07|rcsb pdb:8PVO|rcsb pdb:8PVP|rcsb pdb:8QQB|rcsb pdb:8QWY|rcsb pdb:8QWZ|rcsb pdb:9EPV|rcsb pdb:9EPW|rcsb pdb:9EPX|rcsb pdb:9EPY|rcsb pdb:9EPZ|rcsb pdb:9EQ0|rcsb pdb:9EQ1|rcsb pdb:9EZG|rcsb pdb:9FYF|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|reactome:R-HSA-9755511|reactome:R-HSA-9828806|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|efo:""Orphanet:528084""|panther:PTHR24054(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q7LGA3	intact:EBI-22302424	intact:EBI-5461291|ensembl:ENSP00000359581.4|uniprotkb:D3DT22|uniprotkb:O75036|uniprotkb:Q32NB5|uniprotkb:Q8TAC5|uniprotkb:Q9H441|uniprotkb:Q9NUJ9	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:hs2st_human(display_long)|uniprotkb:HS2ST1(gene name)|psi-mi:HS2ST1(display_short)|uniprotkb:HS2ST(gene name synonym)|uniprotkb:KIAA0448(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000153936.18(gene)|ensembl:ENST00000370550.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004394""(heparan sulfate 2-sulfotransferase activity)|go:""GO:0010467""(gene expression)|go:""GO:0015014""(obsolete heparan sulfate proteoglycan biosynthetic process, chain elongation)|go:""GO:0015015""(obsolete heparan sulfate proteoglycan biosynthetic process, enzymatic modification)|go:""GO:0016020""(membrane)|go:""GO:0030202""(heparin proteoglycan metabolic process)|go:""GO:0060676""(ureteric bud formation)|interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|interpro:IPR007734(Heparan sulphate 2-O-sulphotransferase)|interpro:IPR027417|mint:Q7LGA3|reactome:R-HSA-2022928|refseq:NP_001127964.1|refseq:NP_036394.1|efo:""Orphanet:528084""|panther:PTHR12129(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:96+iUitOmSLSpaEzhZu+9fZXLEQ9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:P19784	intact:EBI-22302424	intact:EBI-347451|ensembl:ENSP00000262506.3	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001887.1|dip:DIP-318N|panther:PTHR24054(orthology-group)|ensembl:ENSG00000070770.10(gene)|ensembl:ENST00000262506.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005956""(protein kinase CK2 complex)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097421""(liver regeneration)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1901524""(regulation of mitophagy)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:1905818""(regulation of chromosome separation)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR045216|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|rcsb pdb:7AT9|rcsb pdb:7ATV|rcsb pdb:7XYH|rcsb pdb:8Q77|rcsb pdb:8Q9S|rcsb pdb:8QBU|rcsb pdb:8QCD|rcsb pdb:8QCG|rcsb pdb:8QF1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|reactome:R-HSA-9755511|reactome:R-HSA-9828806"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:P48729	intact:EBI-22302424	intact:EBI-1383726|uniprotkb:Q96HD2|uniprotkb:Q5U046|uniprotkb:Q5U047|uniprotkb:Q6FGA2|uniprotkb:Q4JJA0|uniprotkb:Q9UDK3|uniprotkb:D3DQG0|uniprotkb:D3DQG1|uniprotkb:Q71TU5|intact:EBI-11048253|ensembl:ENSP00000367074.2	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:kc1a_human(display_long)|uniprotkb:CSNK1A1(gene name)|psi-mi:CSNK1A1(display_short)|uniprotkb:CK1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001020276.1|refseq:NP_001883.4|refseq:NP_001258670.1|refseq:NP_001258671.1|ensembl:ENSG00000113712.19(gene)|ensembl:ENST00000377843.8(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007030""(Golgi organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016607""(nuclear speck)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019082""(viral protein processing)|go:""GO:0030877""(beta-catenin destruction complex)|go:""GO:0031670""(cellular response to nutrient)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0051301""(cell division)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050235|mint:P48729|rcsb pdb:5FQD|rcsb pdb:6GZD|rcsb pdb:7WTT|rcsb pdb:8G66|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5635838|reactome:R-HSA-9694631|dip:DIP-40367N|panther:PTHR11909(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9H0U3	intact:EBI-22302424	intact:EBI-2798816|uniprotkb:B2RAR4|uniprotkb:Q53G00|uniprotkb:Q8NBN6|uniprotkb:D3DTE3|ensembl:ENSP00000354649.6|ensembl:ENSP00000480732.1|uniprotkb:Q6P577	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:magt1_human(display_long)|uniprotkb:IAG2(gene name synonym)|uniprotkb:Implantation-associated protein(gene name synonym)|uniprotkb:MAGT1(gene name)|psi-mi:MAGT1(display_short)|uniprotkb:Magnesium transporter protein 1(gene name synonym)|uniprotkb:PSEC0084(orf name)|uniprotkb:UNQ628/PRO1244(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000102158.22(gene)|ensembl:ENST00000358075.11(transcript)|ensembl:ENST00000618282.5(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0008250""(oligosaccharyltransferase complex)|go:""GO:0015095""(magnesium ion transmembrane transporter activity)|go:""GO:0015693""(magnesium ion transport)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0050890""(cognition)|go:""GO:0055085""(transmembrane transport)|interpro:IPR021149|interpro:IPR036249|mint:Q9H0U3|rcsb pdb:6S7T|reactome:R-HSA-446203|reactome:R-HSA-5223345|reactome:R-HSA-6798695|reactome:R-HSA-9694548|refseq:NP_115497.4|efo:""Orphanet:317476""|panther:PTHR12692(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:M7/LTAlkuCCyeqlTlcJkfu2HU9k9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:O95159	intact:EBI-22302424	intact:EBI-718439|uniprotkb:O14616|uniprotkb:Q9UID0|uniprotkb:A8K7E9|ensembl:ENSP00000294258.3	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:zfpl1_human(display_long)|uniprotkb:Zinc finger protein MCG4(gene name synonym)|uniprotkb:ZFPL1(gene name)|psi-mi:ZFPL1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_006773.2|ensembl:ENSG00000162300.13(gene)|ensembl:ENST00000294258.8(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039043|mint:O95159|panther:PTHR12981(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:8U/G+YcD/pF1Cg44ghFOW+D8tD89606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q96AG4	intact:EBI-22302424	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|uniprotkb:B2RE83|ensembl:ENSP00000225972.7	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_060979.2|ensembl:ENSG00000108829.10(gene)|ensembl:ENST00000225972.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045296""(cadherin binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050216|mint:Q96AG4|panther:PTHR45752(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q15691	intact:EBI-22302424	intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721.5	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_036457.1|refseq:XP_011526998.1|dip:DIP-38018N|ensembl:ENSG00000101367.9(gene)|ensembl:ENST00000375571.6(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0001578""(microtubule bundle formation)|go:""GO:0003723""(RNA binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0005925""(focal adhesion)|go:""GO:0008104""(protein localization)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030981""(cortical microtubule cytoskeleton)|go:""GO:0031110""(regulation of microtubule polymerization or depolymerization)|go:""GO:0031115""(negative regulation of microtubule polymerization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0045296""(cadherin binding)|go:""GO:0031253""(cell projection membrane)|go:""GO:0035371""(microtubule plus-end)|go:""GO:0035372""(protein localization to microtubule)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051233""(spindle midzone)|go:""GO:0051301""(cell division)|go:""GO:0051315""(attachment of mitotic spindle microtubules to kinetochore)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0097431""(mitotic spindle pole)|go:""GO:1902480""(protein localization to mitotic spindle)|go:""GO:1902888""(protein localization to astral microtubule)|go:""GO:1905515""(non-motile cilium assembly)|go:""GO:1905721""(mitotic spindle astral microtubule end)|go:""GO:1990498""(mitotic spindle microtubule)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|panther:PTHR10623(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9P0L0	intact:EBI-22302424	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880.3	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_003565.4|refseq:NP_919415.2|ensembl:ENSG00000101558.14(gene)|ensembl:ENST00000400000.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031982""(vesicle)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035627""(ceramide transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0061025""(membrane fusion)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0090114""(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|dip:DIP-41135N|panther:PTHR10809(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q5HYI8	intact:EBI-22302424	intact:EBI-2824032|uniprotkb:Q8WUD3|ensembl:ENSP00000273375.4	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:rabl3_human(display_long)|uniprotkb:RABL3(gene name)|psi-mi:RABL3(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000144840.10(gene)|ensembl:ENST00000273375.8(transcript)|go:""GO:0001779""(natural killer cell differentiation)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0012505""(endomembrane system)|go:""GO:0030183""(B cell differentiation)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046578""(regulation of Ras protein signal transduction)|go:""GO:0050821""(protein stabilization)|go:""GO:1903059""(regulation of protein lipidation)|interpro:IPR027417|mint:Q5HYI8|refseq:NP_776186.2|efo:""Orphanet:1333""|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:wa/T6PILk7wiphCKdnT3OidKB0E9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q13445	intact:EBI-22302424	intact:EBI-4310995|ensembl:ENSP00000214869.1	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:tmed1_human(display_long)|uniprotkb:TMED1(gene name)|psi-mi:TMED1(display_short)|uniprotkb:IL1RL1L(gene name synonym)|uniprotkb:IL1RL1LG(gene name synonym)|uniprotkb:Interleukin-1 receptor-like 1 ligand(gene name synonym)|uniprotkb:Putative T1/ST2 receptor-binding protein(gene name synonym)|uniprotkb:p24 family protein gamma-1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_006849.1|ensembl:ENSG00000099203.7(gene)|ensembl:ENST00000214869.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0045087""(innate immune response)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q13445|rcsb pdb:7RRM|panther:PTHR22811(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:PQHIGiwN0HhCGcpm1HGn/WF3t9U9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9Y3B3	intact:EBI-22302424	intact:EBI-2561467|uniprotkb:Q96K51|uniprotkb:Q8WUU6|ensembl:ENSP00000405926.3|intact:EBI-10990361|uniprotkb:Q8NBU8	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:tmed7_human(display_long)|uniprotkb:TMED7(gene name)|psi-mi:TMED7(display_short)|uniprotkb:CGI-109(orf name)|uniprotkb:p24 family protein gamma-3(gene name synonym)|uniprotkb:p27(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001157941.1|refseq:NP_861974.1|ensembl:ENSG00000134970.14(gene)|ensembl:ENST00000456936.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0030126""(COPI vesicle coat)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q9Y3B3|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR22811(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:A0B8TdJSOf63pd4GZ65i4VH/M8g9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:P67870	intact:EBI-22302424	intact:EBI-348169|uniprotkb:P07312|uniprotkb:P13862|ensembl:ENSP00000365025.2|ensembl:ENSP00000365026.2|ensembl:ENSP00000365042.3|ensembl:ENSP00000372919.2|ensembl:ENSP00000372925.4|ensembl:ENSP00000382980.1|ensembl:ENSP00000390900.2|ensembl:ENSP00000391038.1|ensembl:ENSP00000393756.1|ensembl:ENSP00000394855.1|ensembl:ENSP00000395275.1|ensembl:ENSP00000400188.2|ensembl:ENSP00000407018.2|ensembl:ENSP00000407379.1|ensembl:ENSP00000409510.1|ensembl:ENSP00000410802.1|ensembl:ENSP00000411322.1|ensembl:ENSP00000412520.1|ensembl:ENSP00000413469.1|ensembl:ENSP00000415237.2|ensembl:ENSP00000415303.2|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000204435.15(gene)|ensembl:ENSG00000206406.9(gene)|ensembl:ENSG00000224398.7(gene)|ensembl:ENSG00000224774.7(gene)|ensembl:ENSG00000228875.8(gene)|ensembl:ENSG00000230700.11(gene)|ensembl:ENSG00000232960.12(gene)|ensembl:ENST00000375865.6(transcript)|ensembl:ENST00000375866.2(transcript)|ensembl:ENST00000375882.7(transcript)|ensembl:ENST00000383427.6(transcript)|ensembl:ENST00000383433.8(transcript)|ensembl:ENST00000400110.5(transcript)|ensembl:ENST00000412802.5(transcript)|ensembl:ENST00000418230.5(transcript)|ensembl:ENST00000422567.6(transcript)|ensembl:ENST00000429633.5(transcript)|ensembl:ENST00000431476.5(transcript)|ensembl:ENST00000436169.5(transcript)|ensembl:ENST00000443673.6(transcript)|ensembl:ENST00000448596.1(transcript)|ensembl:ENST00000451917.6(transcript)|ensembl:ENST00000452985.6(transcript)|ensembl:ENST00000453234.5(transcript)|ensembl:ENST00000454382.6(transcript)|ensembl:ENST00000454511.5(transcript)|ensembl:ENST00000455161.1(transcript)|ensembl:ENST00000458330.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005956""(protein kinase CK2 complex)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016605""(PML body)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032927""(positive regulation of activin receptor signaling pathway)|go:""GO:0033211""(adiponectin-activated signaling pathway)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051101""(regulation of DNA binding)|go:""GO:0060391""(positive regulation of SMAD protein signal transduction)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0075342""(symbiont-mediated disruption of host cell PML body)|go:""GO:1903901""(negative regulation of viral life cycle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:6Q38|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|reactome:R-HSA-9755511|reactome:R-HSA-9828806|refseq:NP_001269314.1|refseq:NP_001311.3|dip:DIP-131N|panther:PTHR11740(orthology-group)|efo:""Orphanet:178469"""	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9NNW5	intact:EBI-22302424	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389.1	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:wdr6_human(display_long)|uniprotkb:WD repeat-containing protein 6(gene name synonym)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_060501.3|panther:PTHR14344(orthology-group)|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252.19(gene)|ensembl:ENST00000608424.6(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002130""(wobble position ribose methylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0030488""(tRNA methylation)|go:""GO:0070314""(G1 to G0 transition)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR051973|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q15006	intact:EBI-22302424	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853.3	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_055488.1|ensembl:ENSG00000104412.8(gene)|ensembl:ENST00000220853.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0042406""(extrinsic component of endoplasmic reticulum membrane)|go:""GO:0045050""(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0072546""(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|interpro:IPR055217|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|rcsb pdb:8EOI|rcsb pdb:8J0N|rcsb pdb:8J0O|rcsb pdb:8S9S|rcsb pdb:9C7V|panther:PTHR12760(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:O94913	intact:EBI-22302424	intact:EBI-2559809|ensembl:ENSP00000298281.4|uniprotkb:Q6P0X8|uniprotkb:A6H8W7|uniprotkb:O43671	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:pcf11_human(display_long)|uniprotkb:PCF11(gene name)|psi-mi:PCF11(display_short)|uniprotkb:KIAA0824(gene name synonym)|uniprotkb:Pre-mRNA cleavage complex II protein Pcf11(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000165494.12(gene)|ensembl:ENST00000298281.8(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005849""(mRNA cleavage factor complex)|go:""GO:0006369""(termination of RNA polymerase II transcription)|go:""GO:0180010""(co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR021605|interpro:IPR045154|interpro:IPR047415|interpro:IPR048829|interpro:IPR048830|interpro:IPR048832|interpro:IPR054127|mint:O94913|rcsb pdb:6WJH|reactome:R-HSA-6807505|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_056969.2|dip:DIP-56825N|panther:PTHR15921(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:UcfmBNhPWm0PbZmQ2LkwK3WvKcU9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:O94988	intact:EBI-22302424	intact:EBI-10962518|uniprotkb:Q8NBA3|uniprotkb:Q24JP0|uniprotkb:Q5PR21|uniprotkb:B4DLC1|ensembl:ENSP00000264344.5	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:fa13a_human(display_long)|uniprotkb:FAM13A(gene name)|psi-mi:FAM13A(display_short)|uniprotkb:FAM13A1(gene name synonym)|uniprotkb:KIAA0914(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"efo:""Orphanet:2032""|ensembl:ENSG00000138640.15(gene)|ensembl:ENST00000264344.10(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039102|mint:O94988|reactome:R-HSA-8980692|reactome:R-HSA-9013149|refseq:NP_001015045.1|refseq:NP_001252507.1|refseq:NP_001252508.1|refseq:NP_001252509.1|refseq:NP_055698.2|refseq:XP_011529818.1|panther:PTHR15904(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:Uwm2VF+xwj4Rc5+KKfgBh7l/M6I9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q7Z2K6	intact:EBI-22302424	intact:EBI-10976398|uniprotkb:B3KSB1|uniprotkb:B2RNA4|uniprotkb:Q9H5M1|uniprotkb:Q8N5T5|ensembl:ENSP00000340427.5|ensembl:ENSP00000417160.1|ensembl:ENSP00000432986.2|ensembl:ENSP00000509092.1|ensembl:ENSP00000509328.1|ensembl:ENSP00000509900.1|ensembl:ENSP00000510190.1	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ermp1_human(display_long)|uniprotkb:ERMP1(gene name)|psi-mi:ERMP1(display_short)|uniprotkb:FXNA(gene name synonym)|uniprotkb:Felix-ina(gene name synonym)|uniprotkb:KIAA1815(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_079172.2|ensembl:ENSG00000099219.15(gene)|ensembl:ENST00000339450.10(transcript)|ensembl:ENST00000462592.5(transcript)|ensembl:ENST00000487088.6(transcript)|ensembl:ENST00000688202.1(transcript)|ensembl:ENST00000689268.1(transcript)|ensembl:ENST00000689364.1(transcript)|ensembl:ENST00000690284.1(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008235""(metalloexopeptidase activity)|go:""GO:0016020""(membrane)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0046872""(metal ion binding)|interpro:IPR007484(Peptidase M28)|interpro:IPR045175|interpro:IPR048024|interpro:IPR053973|interpro:IPR053974|mint:Q7Z2K6|panther:PTHR12147(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:KTUjM61VKt7x03WaW4M8L0OkaJ49606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9NV70	intact:EBI-22302424	intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514.7|ensembl:ENSP00000370695.2	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|refseq:XP_005265807.1|refseq:XP_016863898.1|dip:DIP-37579N|ensembl:ENSG00000090989.18(gene)|ensembl:ENST00000346134.11(transcript)|ensembl:ENST00000381295.7(transcript)|go:""GO:0000145""(exocyst)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051607""(defense response to virus)|go:""GO:0090148""(membrane fission)|go:""GO:0090522""(vesicle tethering involved in exocytosis)|go:""GO:0090543""(Flemming body)|interpro:IPR019160|interpro:IPR028258|interpro:IPR048628|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|panther:PTHR16092(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q96TA2	intact:EBI-22302424	intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV9|uniprotkb:D3DRV8|uniprotkb:B4DNM1|ensembl:ENSP00000318480.3|intact:EBI-10989776	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000136758.21(gene)|ensembl:ENST00000326799.7(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010636""(positive regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034214""(protein hexamerization)|go:""GO:0034982""(mitochondrial protein processing)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664|reactome:R-HSA-9837999|reactome:R-HSA-9840373|refseq:NP_001240795.1|refseq:NP_055078.1|refseq:NP_647473.1|efo:""Orphanet:98676""|panther:PTHR23076(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q96A33	intact:EBI-22302424	intact:EBI-720151|uniprotkb:Q96D00|uniprotkb:Q96JZ7|uniprotkb:Q9H3E4|uniprotkb:Q9NRG3|uniprotkb:B2RAS8|uniprotkb:D3DU20|ensembl:ENSP00000225726.5|ensembl:ENSP00000384888.3	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ccd47_human(display_long)|uniprotkb:CCDC47(gene name)|psi-mi:CCDC47(display_short)|uniprotkb:Calumin(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 47(gene name synonym)|uniprotkb:GK001(orf name)|uniprotkb:MSTP041(orf name)|uniprotkb:PSEC0077(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_064583.2|refseq:XP_005257584.1|ensembl:ENSG00000108588.15(gene)|ensembl:ENST00000225726.10(transcript)|ensembl:ENST00000403162.7(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006983""(ER overload response)|go:""GO:0009791""(post-embryonic development)|go:""GO:0016020""(membrane)|go:""GO:0030867""(rough endoplasmic reticulum membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0036503""(ERAD pathway)|go:""GO:0043022""(ribosome binding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045048""(protein insertion into ER membrane)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0160063""(multi-pass transmembrane protein insertion into ER membrane)|go:""GO:0160064""(multi-pass translocon complex)|interpro:IPR012879(Protein of unknown function DUF1682)|mint:Q96A33|rcsb pdb:6W6L|panther:PTHR12883(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:DdZFzZrrc4culfYoex0Czf/X6SQ9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:P48651	intact:EBI-22302424	intact:EBI-8652106|ensembl:ENSP00000430548.1|uniprotkb:E5RFC5|uniprotkb:Q9BUQ5|intact:MINT-8163942|uniprotkb:B4DE85	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:ptss1_human(display_long)|uniprotkb:PTDSS1(gene name)|psi-mi:PTDSS1(display_short)|uniprotkb:KIAA0024(gene name synonym)|uniprotkb:PSSA(gene name synonym)|uniprotkb:Serine-exchange enzyme I(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000156471.13(gene)|ensembl:ENST00000517309.6(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016740""(transferase activity)|go:""GO:0106245""(L-serine-phosphatidylethanolamine phosphatidyltransferase activity)|go:""GO:0106258""(L-serine-phosphatidylcholine phosphatidyltransferase activity)|interpro:IPR004277(Phosphatidyl serine synthase)|mint:P48651|rcsb pdb:9B4E|rcsb pdb:9B4F|rcsb pdb:9B4G|reactome:R-HSA-1483101|refseq:NP_001277154.1|refseq:NP_055569.1|efo:""Orphanet:2658""|panther:PTHR15362(orthology-group)"	-	-	comment:mint	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:FDSRlCB+/84r8jXnvywHmzAqq9s9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q9Y4P3	intact:EBI-22302424	intact:EBI-2513719|uniprotkb:Q9UQE2|ensembl:ENSP00000307260.4	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:tbl2_human(display_long)|uniprotkb:TBL2(gene name)|psi-mi:TBL2(display_short)|uniprotkb:WBSCR13(gene name synonym)|uniprotkb:WS beta-transducin repeats protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 13 protein(gene name synonym)|uniprotkb:UNQ563/PRO1125(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"ensembl:ENSG00000106638.18(gene)|ensembl:ENST00000305632.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0071456""(cellular response to hypoxia)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR042410|mint:Q9Y4P3|refseq:NP_036585.1|efo:""Orphanet:904""|panther:PTHR44321(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:K0mFwM08LEIAWO/zg4Irplaq9oM9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:O95292	intact:EBI-22302424	intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175.1	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"panther:PTHR10809(orthology-group)|dip:DIP-39816N|efo:""Orphanet:209335""|efo:""Orphanet:803""|ensembl:ENSG00000124164.16(gene)|ensembl:ENST00000475243.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019899""(enzyme binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0044830""(modulation by host of viral RNA genome replication)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046725""(negative regulation by virus of viral protein levels in host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0090114""(COPII-coated vesicle budding)|go:""GO:0090158""(endoplasmic reticulum membrane organization)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|refseq:NP_001182606.1|refseq:NP_004729.1"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:O15258	intact:EBI-22302424	intact:EBI-716910|uniprotkb:O95322|ensembl:ENSP00000464222.1|ensembl:ENSP00000475168.1	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:rer1_human(display_long)|uniprotkb:RER1(gene name)|psi-mi:RER1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_008964.3|refseq:XP_006710369.1|refseq:XP_016855622.1|refseq:XP_016855623.1|refseq:XP_016855624.1|refseq:XP_011538844.1|refseq:XP_011538845.1|ensembl:ENSG00000157916.20(gene)|ensembl:ENST00000488353.2(transcript)|ensembl:ENST00000605895.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006621""(protein retention in ER lumen)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0009986""(cell surface)|go:""GO:0033130""(acetylcholine receptor binding)|go:""GO:0071340""(skeletal muscle acetylcholine-gated channel clustering)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|interpro:IPR004932(Retrieval of early ER protein Rer1)|mint:O15258|panther:PTHR10743(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:rLTZIWGawmaVck0uemR5/E9bFRk9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:O14880	intact:EBI-22302424	intact:EBI-724754|uniprotkb:Q6ICN4|uniprotkb:B2R592|ensembl:ENSP00000356859.1|ensembl:ENSP00000356864.3	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:mgst3_human(display_long)|uniprotkb:MGST3(gene name)|psi-mi:MGST3(display_short)|uniprotkb:Glutathione peroxidase MGST3(gene name synonym)|uniprotkb:LTC4 synthase MGST3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_004519.1|refseq:XP_005245231.2|ensembl:ENSG00000143198.13(gene)|ensembl:ENST00000367884.6(transcript)|ensembl:ENST00000367889.8(transcript)|go:""GO:0004364""(glutathione transferase activity)|go:""GO:0004464""(leukotriene-C4 synthase activity)|go:""GO:0004602""(glutathione peroxidase activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006692""(prostanoid metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0019369""(arachidonate metabolic process)|go:""GO:0019370""(leukotriene biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR001129(""Membrane-associated, eicosanoid and glutathione metabolism (MAPEG)"")|interpro:IPR023352|interpro:IPR050997|mint:O14880|reactome:R-HSA-156590|reactome:R-HSA-5423646|panther:PTHR10250(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:J7fGwczUzRe0yRbrDkBPsHLZkjY9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84008	uniprotkb:Q96B49	intact:EBI-22302424	intact:EBI-10826510|uniprotkb:B2DG15|uniprotkb:Q9UH52|ensembl:ENSP00000381856.3|ensembl:ENSP00000381859.3	psi-mi:y005_chltr(display_long)|uniprotkb:CT_005(locus name)	psi-mi:tom6_human(display_long)|uniprotkb:TOMM6(gene name)|psi-mi:TOMM6(display_short)|uniprotkb:Overexpressed breast tumor protein(gene name synonym)|uniprotkb:Translocase of outer membrane 6 kDa subunit homolog(gene name synonym)|uniprotkb:OBTP(gene name synonym)|uniprotkb:TOM6(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302433|imex:IM-27647-41	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219507.1|refseq:WP_009871351.1|interpro:IPR035355|mint:O84008"	"refseq:NP_001127965.1|ensembl:ENSG00000214736.8(gene)|ensembl:ENST00000398881.4(transcript)|ensembl:ENST00000398884.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0045040""(protein insertion into mitochondrial outer membrane)|go:""GO:0140596""(TOM complex)|interpro:IPR029182|mint:Q96B49|rcsb pdb:7CK6|rcsb pdb:7CP9|rcsb pdb:7VBY|rcsb pdb:7VC4|rcsb pdb:7VD2|rcsb pdb:7VDD|rcsb pdb:8XVA|reactome:R-HSA-1268020|reactome:R-HSA-5205685|panther:PTHR15527(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/25	rogid:EQ9RGs9+Kj81t5ofLs8gBlv/Ai4272561	rogid:j3q/LBZ1XHboUAcHka+T8XtNsIM9606	intact-crc:081E22E6B0A1BC9F|rigid:Uhhw1wDpwCyX63GCy32w1q9e0/I	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84009	uniprotkb:Q13308	intact:EBI-22302493	intact:EBI-2803245|uniprotkb:Q8NFA6|uniprotkb:Q5T650|uniprotkb:Q8NFA8|uniprotkb:Q13417|uniprotkb:Q6IQ54|uniprotkb:Q8NFA5|uniprotkb:Q8NFA7|uniprotkb:A8K974|uniprotkb:B7Z477|uniprotkb:E9PFZ5|ensembl:ENSP00000230419.4	psi-mi:y006_chltr(display_long)|uniprotkb:CT_006(locus name)	psi-mi:ptk7_human(display_long)|uniprotkb:CCK4(gene name synonym)|uniprotkb:Colon carcinoma kinase 4(gene name synonym)|uniprotkb:Protein-tyrosine kinase 7(gene name synonym)|uniprotkb:PTK7(gene name)|psi-mi:PTK7(display_short)|uniprotkb:Pseudo tyrosine kinase receptor 7(gene name synonym)|uniprotkb:Tyrosine-protein kinase-like 7(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302502|imex:IM-27647-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219508.1|refseq:WP_009871352.1|interpro:IPR035358|mint:O84009"	"refseq:NP_001257327.1|refseq:NP_002812.2|refseq:NP_690619.1|refseq:NP_690620.1|refseq:NP_690621.1|ensembl:ENSG00000112655.16(gene)|ensembl:ENST00000230419.9(transcript)|go:""GO:0001736""(establishment of planar polarity)|go:""GO:0001822""(kidney development)|go:""GO:0001843""(neural tube closure)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003401""(axis elongation)|go:""GO:0004672""(protein kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007165""(signal transduction)|go:""GO:0008046""(axon guidance receptor activity)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016477""(cell migration)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030424""(axon)|go:""GO:0042060""(wound healing)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0050808""(synapse organization)|go:""GO:0060026""(convergent extension)|go:""GO:0060484""(lung-associated mesenchyme development)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0060976""(coronary vasculature development)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0090103""(cochlea morphogenesis)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050958|mint:Q13308|rcsb pdb:6VG3|panther:PTHR45080(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:F8nnTiew8jgaGltw+2w6cxGEHjk272561	rogid:O4L3LFD0WvN1hDb1abqVBbW1gis9606	intact-crc:091359075A686E88|rigid:YXjQyhmENVJ/gaPUU8GMPTpPKbY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84009	uniprotkb:P61981	intact:EBI-22302493	intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330.3	psi-mi:y006_chltr(display_long)|uniprotkb:CT_006(locus name)	psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302502|imex:IM-27647-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219508.1|refseq:WP_009871352.1|interpro:IPR035358|mint:O84009"	"efo:""Orphanet:442835""|rcsb pdb:6A5S|rcsb pdb:6BYJ|ensembl:ENSG00000170027.7(gene)|ensembl:ENST00000307630.5(transcript)|go:""GO:0002842""(positive regulation of T cell mediated immune response to tumor cell)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008426""(protein kinase C inhibitor activity)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022409""(positive regulation of cell-cell adhesion)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045664""(regulation of neuron differentiation)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098793""(presynapse)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|rcsb pdb:6ZBT|rcsb pdb:6ZC9|rcsb pdb:7A6R|rcsb pdb:7A6Y|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_036611.2|dip:DIP-33406N|panther:PTHR18860(orthology-group)|ensembl:ENSP00000306330.3"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:F8nnTiew8jgaGltw+2w6cxGEHjk272561	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606	intact-crc:091359075A686E88|rigid:YXjQyhmENVJ/gaPUU8GMPTpPKbY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84009	uniprotkb:P31946	intact:EBI-22302493	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161.4|ensembl:ENSP00000361930.3	psi-mi:y006_chltr(display_long)|uniprotkb:CT_006(locus name)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302502|imex:IM-27647-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219508.1|refseq:WP_009871352.1|interpro:IPR035358|mint:O84009"	"panther:PTHR18860(orthology-group)|refseq:NP_003395.1|refseq:NP_647539.1|ensembl:ENSG00000166913.13(gene)|ensembl:ENST00000353703.9(transcript)|ensembl:ENST00000372839.7(transcript)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|rcsb pdb:8DP5|rcsb pdb:8EQ8|rcsb pdb:8EQH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9726840|reactome:R-HSA-9726842|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:XP_016883528.1|dip:DIP-743N|ensembl:ENSP00000300161.4|ensembl:ENSP00000361930.3"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:F8nnTiew8jgaGltw+2w6cxGEHjk272561	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	intact-crc:091359075A686E88|rigid:YXjQyhmENVJ/gaPUU8GMPTpPKbY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84009	uniprotkb:Q04917	intact:EBI-22302493	intact:EBI-306940|intact:EBI-11759595|ensembl:ENSP00000248975.5|intact:EBI-21351354	psi-mi:y006_chltr(display_long)|uniprotkb:CT_006(locus name)	psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302502|imex:IM-27647-81	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219508.1|refseq:WP_009871352.1|interpro:IPR035358|mint:O84009"	"refseq:NP_003396.1|ensembl:ENSG00000128245.15(gene)|ensembl:ENST00000248975.6(transcript)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0003779""(actin binding)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006713""(glucocorticoid catabolic process)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0014704""(intercalated disc)|go:""GO:0017080""(sodium channel regulator activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0035259""(nuclear glucocorticoid receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042921""(nuclear receptor-mediated glucocorticoid signaling pathway)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045664""(regulation of neuron differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0050774""(negative regulation of dendrite morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0086010""(membrane depolarization during action potential)|go:""GO:0098793""(presynapse)|go:""GO:0099171""(presynaptic modulation of chemical synaptic transmission)|go:""GO:0150048""(cerebellar granule cell to Purkinje cell synapse)|go:""GO:2000649""(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|rcsb pdb:7NMZ|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9735871|reactome:R-HSA-9755779|dip:DIP-27566N|ensembl:ENSP00000248975.5|panther:PTHR18860(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:F8nnTiew8jgaGltw+2w6cxGEHjk272561	rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606	intact-crc:091359075A686E88|rigid:YXjQyhmENVJ/gaPUU8GMPTpPKbY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84039	uniprotkb:O14967	intact:EBI-22302511	intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699.5|ensembl:ENSP00000392782.1	psi-mi:y036_chltr(display_long)|uniprotkb:CT_036(locus name)	psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302519|imex:IM-27647-61	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|refseq:NP_219538.1|refseq:WP_010724994.1|mint:O84039"	"refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132.13(gene)|ensembl:ENST00000325617.10(transcript)|ensembl:ENST00000414773.5(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006457""(protein folding)|go:""GO:0007338""(single fertilization)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0036503""(ERAD pathway)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967|panther:PTHR11073(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:D6ARk/Mp8W+Kpqkk3xLQyADkav4272561	rogid:Akb2XoiNjob34njC2erE11yg80w9606	intact-crc:A4EF73CCA0389A41|rigid:WkN+a6UmB0RXBY/DXr/edt8fftA	false	binding-associated region:52-403|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:Q8IXB1	intact:EBI-22302545	intact:EBI-2949763|uniprotkb:Q53QT7|uniprotkb:Q6UWZ6|uniprotkb:Q96K44|uniprotkb:Q8NC82|uniprotkb:Q86T61|uniprotkb:Q9NSY6|uniprotkb:Q17RJ6|uniprotkb:Q8TD87|uniprotkb:Q96K54|uniprotkb:Q96K38|uniprotkb:Q4ZG06|uniprotkb:Q3B7W8|ensembl:ENSP00000264065.6	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	psi-mi:djc10_human(display_long)|uniprotkb:DNAJC10(gene name)|psi-mi:DNAJC10(display_short)|uniprotkb:ERDJ5(gene name synonym)|uniprotkb:Macrothioredoxin(gene name synonym)|uniprotkb:UNQ495/PRO1012(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 5(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"refseq:NP_061854.1|refseq:NP_001258510.1|dip:DIP-48947N|ensembl:ENSG00000077232.19(gene)|ensembl:ENST00000264065.12(transcript)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0016020""(membrane)|go:""GO:0016671""(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0036503""(ERAD pathway)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR021170|interpro:IPR035673|interpro:IPR035674|interpro:IPR036249|interpro:IPR036869|interpro:IPR052460|mint:Q8IXB1|panther:PTHR44340(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:sD/pp49jws0LrBjwCxQmZqzfR9U9606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:Q32P28	intact:EBI-22302545	intact:EBI-396328|uniprotkb:Q96SK8|uniprotkb:Q7KZR4|uniprotkb:Q96BR8|uniprotkb:Q96SL5|uniprotkb:Q96SN3|uniprotkb:Q9H6K3|uniprotkb:Q9HC86|uniprotkb:Q9HC87|intact:EBI-2555416|ensembl:ENSP00000296388.5	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	psi-mi:p3h1_human(display_long)|uniprotkb:P3H1(gene name)|psi-mi:P3H1(display_short)|uniprotkb:GROS1(gene name synonym)|uniprotkb:Growth suppressor 1(gene name synonym)|uniprotkb:LEPRE1(gene name synonym)|uniprotkb:Leucine- and proline-enriched proteoglycan 1(gene name synonym)|uniprotkb:PSEC0109(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"ensembl:ENSG00000117385.16(gene)|ensembl:ENST00000296388.10(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006457""(protein folding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016020""(membrane)|go:""GO:0018126""(protein hydroxylation)|go:""GO:0019797""(procollagen-proline 3-dioxygenase activity)|go:""GO:0031418""(L-ascorbic acid binding)|go:""GO:0032963""(collagen metabolic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0050708""(regulation of protein secretion)|go:""GO:0050821""(protein stabilization)|go:""GO:0060348""(bone development)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1901874""(negative regulation of post-translational protein modification)|interpro:IPR005123(""2OG-Fe(II) oxygenase"")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR039575|interpro:IPR044862|mint:Q32P28|rcsb pdb:8K0E|rcsb pdb:8K0F|rcsb pdb:8K0I|rcsb pdb:8K0M|rcsb pdb:8K17|rcsb pdb:8KC9|reactome:R-HSA-1650814|refseq:NP_001139761.1|refseq:NP_001230175.1|refseq:NP_071751.3|efo:""Orphanet:216804""|efo:""Orphanet:216812""|panther:PTHR14049(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:L3euuYyawz69NXv4u6baW/ceVdU9606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:Q6NUQ4	intact:EBI-22302545	intact:EBI-372318|uniprotkb:A6NNF2|uniprotkb:Q53SW1|uniprotkb:Q69YH4|uniprotkb:Q8WZ37|uniprotkb:Q9NXH2|uniprotkb:Q8NC45|ensembl:ENSP00000238788.9|ensembl:ENSP00000319469.7|uniprotkb:B3KUI9|uniprotkb:B5MCD8|uniprotkb:D6W547	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	psi-mi:tm214_human(display_long)|uniprotkb:TMEM214(gene name)|psi-mi:TMEM214(display_short)|uniprotkb:PP446(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"ensembl:ENSG00000119777.20(gene)|ensembl:ENST00000238788.14(transcript)|ensembl:ENST00000321326.11(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0006915""(apoptotic process)|interpro:IPR019308|mint:Q6NUQ4|refseq:NP_001077059.1|refseq:NP_060197.4|panther:PTHR13448(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:Yx4jp39AqeiXqOJVzMMRqRgk8449606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:P55345	intact:EBI-22302545	intact:EBI-78458|uniprotkb:P78350|uniprotkb:Q9BW15|uniprotkb:Q9UMC2|uniprotkb:Q6FHF0|uniprotkb:Q99781|uniprotkb:Q498Y5|uniprotkb:B7U630|uniprotkb:B7U631|uniprotkb:B7U632|uniprotkb:Q5U7D4|ensembl:ENSP00000347906.3|ensembl:ENSP00000380759.1|ensembl:ENSP00000380760.2	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	psi-mi:anm2_human(display_long)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"refseq:NP_001526.2|refseq:NP_996845.1|panther:PTHR11006(orthology-group)|refseq:NP_001273605.1|refseq:NP_001273606.1|refseq:NP_001273607.1|refseq:NP_001229794.1|refseq:NP_001229793.1|refseq:XP_005261168.1|refseq:XP_006724061.1|refseq:NP_001229795.1|refseq:XP_006724063.1|ensembl:ENSG00000160310.20(gene)|ensembl:ENST00000355680.8(transcript)|ensembl:ENST00000397637.5(transcript)|ensembl:ENST00000397638.7(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006479""(protein methylation)|go:""GO:0007165""(signal transduction)|go:""GO:0016274""(protein-arginine N-methyltransferase activity)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0033142""(nuclear progesterone receptor binding)|go:""GO:0035242""(protein-arginine omega-N asymmetric methyltransferase activity)|go:""GO:0035642""(histone H3R17 methyltransferase activity)|go:""GO:0042054""(histone methyltransferase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0042975""(peroxisome proliferator activated receptor binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0044020""(histone H4R3 methyltransferase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048588""(developmental cell growth)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0060765""(regulation of androgen receptor signaling pathway)|go:""GO:0062122""(histone H3K37 methyltransferase activity)|go:""GO:0070611""(histone H3R2 methyltransferase activity)|go:""GO:0140592""(histone H3R8 methyltransferase activity)|go:""GO:0140759""(histone H3K56 methyltransferase activity)|go:""GO:0140903""(histone H3R26 methyltransferase activity)|go:""GO:0140938""(histone H3 methyltransferase activity)|go:""GO:0140984""(histone H4K12 methyltransferase activity)|go:""GO:1990259""(histone H2A Q104 methyltransferase activity)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR007848(Methyltransferase small)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036028|interpro:IPR055135|mint:P55345|rcsb pdb:1X2P"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:+xna8Cy+5sQWV6hvKfg4rNrQKBw9606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:O60613	intact:EBI-22302545	intact:EBI-1052797|uniprotkb:Q4GZG7|uniprotkb:Q8WU00|uniprotkb:Q9BS64|uniprotkb:Q9GZW0|uniprotkb:Q9NR01|uniprotkb:A0A0B4J1S4|ensembl:ENSP00000328729.6	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	psi-mi:sep15_human(display_long)|uniprotkb:SELENOF(gene name)|psi-mi:SELENOF(display_short)|uniprotkb:15 kDa selenoprotein(gene name synonym)|uniprotkb:SEP15(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"refseq:NP_004252.2|refseq:NP_976086.1|ensembl:ENSG00000183291.18(gene)|ensembl:ENST00000331835.10(transcript)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0008430""(selenium binding)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0035092""(sperm DNA condensation)|go:""GO:0051084""('de novo' post-translational protein folding)|interpro:IPR014912(Sep15/SelM redox)|interpro:IPR036249|interpro:IPR038219|interpro:IPR039992|mint:O60613|panther:PTHR13077(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:O+C59EK6dpYLDbHWrJT10RtGus89606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:Q9NYU2	intact:EBI-22302545	intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253.6	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	"psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:""UDP--Glc:glycoprotein glucosyltransferase""(gene name synonym)|uniprotkb:UGCGL1(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"refseq:NP_064505.1|go:""GO:0051082""(unfolded protein binding)|ensembl:ENSG00000136731.13(gene)|ensembl:ENST00000259253.11(transcript)|go:""GO:0003980""(""UDP-glucose:glycoprotein glucosyltransferase activity"")|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036503""(ERAD pathway)|go:""GO:0044322""(endoplasmic reticulum quality control compartment)|go:""GO:0051084""('de novo' post-translational protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904380""(endoplasmic reticulum mannose trimming)|interpro:IPR009448(""UDP-glucose:Glycoprotein Glucosyltransferase"")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032|panther:PTHR11226(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:O14967	intact:EBI-22302545	intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699.5|ensembl:ENSP00000392782.1	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132.13(gene)|ensembl:ENST00000325617.10(transcript)|ensembl:ENST00000414773.5(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006457""(protein folding)|go:""GO:0007338""(single fertilization)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0036503""(ERAD pathway)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967|panther:PTHR11073(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:Akb2XoiNjob34njC2erE11yg80w9606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:P07237	intact:EBI-22302545	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801.4	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"panther:PTHR18929(orthology-group)|ensembl:ENSG00000185624.16(gene)|ensembl:ENST00000331483.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0003779""(actin binding)|go:""GO:0004656""(procollagen-proline 4-dioxygenase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0016222""(procollagen-proline 4-dioxygenase complex)|go:""GO:0016972""(thiol oxidase activity)|go:""GO:0018401""(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:""GO:0019899""(enzyme binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030070""(insulin processing)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035722""(interleukin-12-mediated signaling pathway)|go:""GO:0038155""(interleukin-23-mediated signaling pathway)|go:""GO:0042470""(melanosome)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902175""(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|rcsb pdb:7ZSC|rcsb pdb:8EOJ|rcsb pdb:8GDY|reactome:R-HSA-1650814|reactome:R-HSA-264876|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8964041|reactome:R-HSA-9020591|reactome:R-HSA-9020933|refseq:NP_000909.2|efo:""Orphanet:2050""|efo:""Orphanet:216796""|dip:DIP-32979N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:Q15165	intact:EBI-22302545	intact:EBI-3909798|uniprotkb:O15114|uniprotkb:B4DJD5|uniprotkb:Q5FBX7|uniprotkb:O15115|uniprotkb:B2RCP9|uniprotkb:Q86YL0|uniprotkb:O75856|uniprotkb:A4D1H7|intact:EBI-10966394|ensembl:ENSP00000222572.3|ensembl:ENSP00000488838.1	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	psi-mi:pon2_human(display_long)|uniprotkb:PON2(gene name)|psi-mi:PON2(display_short)|uniprotkb:Aromatic esterase 2(gene name synonym)|uniprotkb:Serum aryldialkylphosphatase 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"dip:DIP-61136N|ensembl:ENSG00000105854.13(gene)|ensembl:ENST00000222572.8(transcript)|ensembl:ENST00000633531.1(transcript)|go:""GO:0004064""(arylesterase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009636""(response to toxic substance)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0102007""(acyl-L-homoserine-lactone lactonohydrolase activity)|go:""GO:1901335""(lactone catabolic process)|interpro:IPR002640(Arylesterase)|interpro:IPR008364(Paraoxonase2)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR051288|mint:Q15165|reactome:R-HSA-2142688|refseq:NP_000296.2|refseq:NP_001018171.1|efo:""Orphanet:803""|panther:PTHR11799(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:9zE87aut0R8eYxaXM+HgYsJxLYI9606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:O60220	intact:EBI-22302545	intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993.3	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"ensembl:ENSG00000126953.8(gene)|ensembl:ENST00000372902.4(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0007399""(nervous system development)|go:""GO:0042719""(mitochondrial intermembrane space protein transporter complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0045039""(protein insertion into mitochondrial inner membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|mint:O60220|reactome:R-HSA-1268020|refseq:NP_004076.1|efo:""Orphanet:52368""|panther:PTHR19338(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84061	uniprotkb:Q9Y5J9	intact:EBI-22302545	intact:EBI-1049085|uniprotkb:Q3KQS9|uniprotkb:Q9UN04|uniprotkb:B0YJA5|ensembl:ENSP00000422122.2	psi-mi:o84061_chltr(display_long)|uniprotkb:CT_058(locus name)	psi-mi:tim8b_human(display_long)|uniprotkb:Deafness dystonia protein 2(gene name synonym)|uniprotkb:DDP-like protein(gene name synonym)|uniprotkb:TIM8B(gene name synonym)|uniprotkb:TIMM8B(gene name)|psi-mi:TIMM8B(display_short)|uniprotkb:DDP2(gene name synonym)|uniprotkb:DDPL(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302553|imex:IM-27647-43	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219561.1|refseq:WP_010725013.1|interpro:IPR002589(Appr-1-p processing)|mint:O84061"	"refseq:NP_036591.2|ensembl:ENSG00000150779.12(gene)|ensembl:ENST00000504148.3(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042719""(mitochondrial intermembrane space protein transporter complex)|go:""GO:0045039""(protein insertion into mitochondrial inner membrane)|go:""GO:0140318""(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|mint:Q9Y5J9|reactome:R-HSA-1268020|panther:PTHR19338(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:ro3pR4wbBRsPVSXiBJeoJrBN09M272561	rogid:7DK/1BIkwyl9KMIgEFWqRhZn2ZE9606	intact-crc:FAA4EFC07C00ADCA|rigid:IOkjQ26/57f6/HLsPHo5Dbdbuaw	false	strep tag:c-c|binding-associated region:57-367	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q6DD88	uniprotkb:O84137	intact:EBI-6165882|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1|ensembl:ENSP00000381844.3	intact:EBI-22302573	psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short)	psi-mi:o84137_chltr(display_long)|uniprotkb:CT_135(locus name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272561(chltr)|taxid:272561(chltr)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302580|imex:IM-27647-83	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000184743.13(gene)|ensembl:ENST00000398868.8(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0098826""(endoplasmic reticulum tubular network membrane)|go:""GO:1903373""(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|refseq:NP_001276977.1|refseq:NP_056274.3|efo:""Orphanet:36386""|panther:PTHR10751(orthology-group)"	"go:""GO:0016020""(membrane)|refseq:NP_219638.1|refseq:WP_009873048.1|mint:O84137"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606	rogid:8IsEuju3fvTl5kH9oZp4jHGWyOs272561	intact-crc:AB3641F6CE4AB122|rigid:X/Z6tpoX+1CTQuIPV553NtW7WGg	false	-	binding-associated region:57-360|strep tag:c-c	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:P08519	intact:EBI-22302591	intact:EBI-9232288|uniprotkb:Q5VTD7|uniprotkb:Q9UD88|ensembl:ENSP00000321334.6	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:apoa_human(display_long)|uniprotkb:LPA(gene name)|psi-mi:LPA(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"refseq:NP_005568.2|ensembl:ENSG00000198670.13(gene)|ensembl:ENST00000316300.10(transcript)|go:""GO:0001968""(fibronectin binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006869""(lipid transport)|go:""GO:0008015""(blood circulation)|go:""GO:0008201""(heparin binding)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0034358""(plasma lipoprotein particle)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|interpro:IPR050759|mint:P08519|rcsb pdb:1I71|rcsb pdb:1JFN|rcsb pdb:1KIV|rcsb pdb:2FEB|rcsb pdb:3KIV|rcsb pdb:4BV5|rcsb pdb:4BV7|rcsb pdb:4BVC|rcsb pdb:4BVD|rcsb pdb:4BVV|rcsb pdb:4BVW|rcsb pdb:4KIV|rcsb pdb:6RX7|rcsb pdb:8TCE|rcsb pdb:8V8Z|rcsb pdb:8V9B|reactome:R-HSA-8964041|panther:PTHR20851(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:cWuHYqUe4koLC8b9Jg55fNKdSIA9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:Q14203	intact:EBI-22302591	intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300|ensembl:ENSP00000487279.2	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"efo:""Orphanet:139589""|efo:""Orphanet:178509""|efo:""Orphanet:803""|ensembl:ENSG00000204843.13(gene)|ensembl:ENST00000628224.3(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0000922""(spindle pole)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005938""(cell cortex)|go:""GO:0007097""(nuclear migration)|go:""GO:0007399""(nervous system development)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0008017""(microtubule binding)|go:""GO:0010457""(centriole-centriole cohesion)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015631""(tubulin binding)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021517""(ventral spinal cord development)|go:""GO:0030286""(dynein complex)|go:""GO:0030424""(axon)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031252""(cell leading edge)|go:""GO:0032402""(melanosome transport)|go:""GO:0034454""(microtubule anchoring at centrosome)|go:""GO:0035371""(microtubule plus-end)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045171""(intercellular bridge)|go:""GO:0048156""(tau protein binding)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051081""(nuclear membrane disassembly)|go:""GO:0051301""(cell division)|go:""GO:0060236""(regulation of mitotic spindle organization)|go:""GO:0061744""(motor behavior)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:0099558""(maintenance of synapse structure)|go:""GO:0099738""(cell cortex region)|go:""GO:0120103""(centriolar subdistal appendage)|go:""GO:1904398""(positive regulation of neuromuscular junction development)|go:""GO:1905515""(non-motile cilium assembly)|go:""GO:1990535""(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-9725370|refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177765.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|dip:DIP-31365N|panther:PTHR18916(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:Q9UJW0	intact:EBI-22302591	intact:EBI-2134033|uniprotkb:Q8TAN8|uniprotkb:D3DQH0|intact:EBI-2559420|uniprotkb:B3KWW0|uniprotkb:E5RGT5|ensembl:ENSP00000416968.2	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:dctn4_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)|uniprotkb:Dynactin subunit p62(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"ensembl:ENSG00000132912.14(gene)|ensembl:ENST00000447998.7(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000922""(spindle pole)|go:""GO:0001725""(stress fiber)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005868""(cytoplasmic dynein complex)|go:""GO:0005869""(dynactin complex)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0030017""(sarcomere)|interpro:IPR008603(Dynactin p62)|mint:Q9UJW0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|refseq:NP_001129115.1|refseq:NP_001129116.1|refseq:NP_057305.1|refseq:XP_011535946.1|refseq:XP_011535947.1|efo:""Orphanet:586""|panther:PTHR13034(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:JradQZl06O4u9N3HH+cpvdP05RA9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:Q9NZ32	intact:EBI-22302591	intact:EBI-2559426|ensembl:ENSP00000254286.4|uniprotkb:Q9H9Y5|uniprotkb:Q9NWY2	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:arp10_human(display_long)|uniprotkb:ACTR10(gene name)|psi-mi:ACTR10(display_short)|uniprotkb:ACTR11(gene name synonym)|uniprotkb:ARP11(gene name synonym)|uniprotkb:Actin-related protein 11(gene name synonym)|uniprotkb:ARP10(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"ensembl:ENSG00000131966.14(gene)|ensembl:ENST00000254286.9(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0098958""(retrograde axonal transport of mitochondrion)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR004000(Actin/actin-like)|interpro:IPR043129|mint:Q9NZ32|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|refseq:NP_060947.1|panther:PTHR11937(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:zP8oC2X4zksg1YC89SF2yerpa6I9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:Q13561	intact:EBI-22302591	intact:EBI-715074|uniprotkb:Q86YN2|uniprotkb:Q9BW17|uniprotkb:B2RBK5|ensembl:ENSP00000447824.1	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:dctn2_human(display_long)|uniprotkb:Dynactin complex 50 kDa subunit(gene name synonym)|uniprotkb:50 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:p50 dynamitin(gene name synonym)|uniprotkb:DCTN2(gene name)|psi-mi:DCTN2(display_short)|uniprotkb:DCTN50(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"go:""GO:0005869""(dynactin complex)|go:""GO:0005874""(microtubule)|ensembl:ENSG00000175203.17(gene)|ensembl:ENST00000548249.6(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030286""(dynein complex)|go:""GO:0030426""(growth cone)|go:""GO:0030507""(spectrin binding)|go:""GO:0031982""(vesicle)|go:""GO:0032402""(melanosome transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071539""(protein localization to centrosome)|interpro:IPR028133|mint:Q13561|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|refseq:NP_001248341.1|refseq:NP_001248342.1|dip:DIP-37545N|refseq:NP_006391.1|panther:PTHR15346(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:JrL5jUtArek+zqmCkPKomnjuSf09606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:P42025	intact:EBI-22302591	intact:EBI-367493|uniprotkb:Q53SK5|uniprotkb:Q9BRB7|uniprotkb:D3DVH2|ensembl:ENSP00000289228.5|ensembl:ENSP00000517084.1	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:acty_human(display_long)|uniprotkb:ACTR1B(gene name)|psi-mi:ACTR1B(display_short)|uniprotkb:Actin-related protein 1B(gene name synonym)|uniprotkb:CTRN2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"refseq:NP_005726.1|ensembl:ENSG00000115073.8(gene)|ensembl:ENSG00000291597.1(gene)|ensembl:ENST00000289228.7(transcript)|ensembl:ENST00000708081.1(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P42025|reactome:R-HSA-2132295|reactome:R-HSA-6798695|panther:PTHR11937(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:FUpYgmLV3BdkZIlZGyC6L5kR+wE9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:Q12792	intact:EBI-22302591	intact:EBI-1056675|uniprotkb:Q6NUK9|uniprotkb:A8K5A8|uniprotkb:Q59G07|uniprotkb:Q5U0B1|uniprotkb:Q6FHJ1|uniprotkb:Q6FHL6|uniprotkb:Q86XL6|uniprotkb:Q8TCD3|uniprotkb:B3KXS6|uniprotkb:B4DLX9|ensembl:ENSP00000378886.2	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:twf1_human(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:PTK9(gene name synonym)|uniprotkb:Protein A6(gene name synonym)|uniprotkb:Protein tyrosine kinase 9(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"refseq:NP_001229326.1|refseq:NP_002813.3|ensembl:ENSG00000151239.14(gene)|ensembl:ENST00000395510.7(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0003785""(actin monomer binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010613""(positive regulation of cardiac muscle hypertrophy)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030016""(myofibril)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030175""(filopodium)|go:""GO:0030837""(negative regulation of actin filament polymerization)|go:""GO:0032587""(ruffle membrane)|go:""GO:0042989""(obsolete sequestering of actin monomers)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|mint:Q12792|rcsb pdb:7CCC|reactome:R-HSA-9013418|reactome:R-HSA-9662360|reactome:R-HSA-9662361|panther:PTHR13759(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:5yv7DC8rsBmxmXtzv40wJ/U154c9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:Q14192	intact:EBI-22302591	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:O00399	intact:EBI-22302591	intact:EBI-2559415|ensembl:ENSP00000221114.3|uniprotkb:B2RAC1	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"ensembl:ENSG00000104671.8(gene)|ensembl:ENST00000221114.8(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0070840""(dynein complex binding)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|refseq:NP_006562.1|panther:PTHR13072(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:O75935	intact:EBI-22302591	intact:EBI-347442|uniprotkb:A6NII7|uniprotkb:Q5T1I7|uniprotkb:Q5T1I5|uniprotkb:Q5T8G3|uniprotkb:Q9BPU8|uniprotkb:B2RBM5|ensembl:ENSP00000259632.7	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:dctn3_human(display_long)|uniprotkb:DCTN22(gene name synonym)|uniprotkb:DCTN3(gene name)|psi-mi:DCTN3(display_short)|uniprotkb:Dynactin complex subunit 22 kDa subunit(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"refseq:NP_009165.1|refseq:NP_077324.1|refseq:NP_001268354.1|refseq:NP_001268355.1|panther:PTHR28360(orthology-group)|ensembl:ENSG00000137100.16(gene)|ensembl:ENST00000259632.12(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0007017""(microtubule-based process)|go:""GO:0030496""(midbody)|go:""GO:0032154""(cleavage furrow)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061640""(cytoskeleton-dependent cytokinesis)|interpro:IPR009991(Dynactin subunit p22)|mint:O75935|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:KPLiGDMa0KR/H31QtEdl2YiwYzk9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:Q9BTE1	intact:EBI-22302591	intact:EBI-747324|ensembl:ENSP00000300087.2|uniprotkb:H3BN51|uniprotkb:A8K9X8|uniprotkb:H3BQA4	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:dctn5_human(display_long)|uniprotkb:Dynactin subunit p25(gene name synonym)|uniprotkb:DCTN5(gene name)|psi-mi:DCTN5(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"refseq:NP_115875.1|ensembl:ENSG00000166847.10(gene)|ensembl:ENST00000300087.7(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0003281""(ventricular septum development)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035904""(aorta development)|go:""GO:0060976""(coronary vasculature development)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR047125|mint:Q9BTE1|rcsb pdb:5NW4|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|refseq:NP_001186672.1|refseq:NP_001185940.1|panther:PTHR46126(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:/aCDlJJ8PO7etMT4aZxg1i5WtYE9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84166	uniprotkb:P61163	intact:EBI-22302591	intact:EBI-774234|uniprotkb:P42024|uniprotkb:B2R6B0|ensembl:ENSP00000358921.4	psi-mi:o84166_chltr(display_long)|uniprotkb:CT_164(locus name)	psi-mi:actz_human(display_long)|uniprotkb:Centrosome-associated actin homolog(gene name synonym)|uniprotkb:Actin-RPV(gene name synonym)|uniprotkb:ARP1(gene name synonym)|uniprotkb:ACTR1A(gene name)|psi-mi:ACTR1A(display_short)|uniprotkb:CTRN1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302598|imex:IM-27647-45	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219667.1|refseq:WP_010725105.1|mint:O84166"	"refseq:NP_005727.1|ensembl:ENSG00000138107.13(gene)|ensembl:ENST00000369905.9(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005869""(dynactin complex)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005938""(cell cortex)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0070062""(extracellular exosome)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P61163|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|panther:PTHR11937(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:LCGF3HTZwhAWieL9EdyKWWyYPJ4272561	rogid:aJHKOSj1qmZ7Pk8aZAyWWd8DEdw9606	intact-crc:86C68A3C6AE49839|rigid:CP6JqO48XdcInkBMSxfTKS+A/tQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84198	uniprotkb:P54727	intact:EBI-22302615	intact:EBI-954531|uniprotkb:Q8WUB0|uniprotkb:B3KWK8|uniprotkb:G5E9P0|uniprotkb:Q7Z5K8|ensembl:ENSP00000350708.3	psi-mi:o84198_chltr(display_long)|uniprotkb:CT_195(locus name)	psi-mi:rd23b_human(display_long)|uniprotkb:XP-C repair-complementing complex 58 kDa protein(gene name synonym)|uniprotkb:RAD23B(gene name)|psi-mi:RAD23B(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302622|imex:IM-27647-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219699.1|refseq:WP_010725118.1|mint:O84198"	"refseq:NP_002865.1|refseq:NP_001231653.1|dip:DIP-39944N|ensembl:ENSG00000119318.13(gene)|ensembl:ENST00000358015.8(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0007283""(spermatogenesis)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0032434""(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070628""(proteasome binding)|go:""GO:0071942""(XPC complex)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:0140612""(DNA damage sensor activity)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|interpro:IPR041811|mint:P54727|rcsb pdb:1P1A|rcsb pdb:1PVE|rcsb pdb:1UEL|rcsb pdb:8EBS|rcsb pdb:8EBV|rcsb pdb:8EBW|reactome:R-HSA-532668|reactome:R-HSA-5689877|reactome:R-HSA-5696394|reactome:R-HSA-5696395|panther:PTHR10621(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:j0Kp4k//hsLl+Z1Er9tJyOPMeTM272561	rogid:msyh4+G2TzDW+xgGjixPKWWrjRE9606	intact-crc:1AD5047F5C386BDB|rigid:lATlSScRobTKDWyAYNIAoUfyM5k	false	strep tag:c-c|binding-associated region:212-363	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84198	uniprotkb:O60220	intact:EBI-22302615	intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993.3	psi-mi:o84198_chltr(display_long)|uniprotkb:CT_195(locus name)	psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302622|imex:IM-27647-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219699.1|refseq:WP_010725118.1|mint:O84198"	"ensembl:ENSG00000126953.8(gene)|ensembl:ENST00000372902.4(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0007399""(nervous system development)|go:""GO:0042719""(mitochondrial intermembrane space protein transporter complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0045039""(protein insertion into mitochondrial inner membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|mint:O60220|reactome:R-HSA-1268020|refseq:NP_004076.1|efo:""Orphanet:52368""|panther:PTHR19338(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:j0Kp4k//hsLl+Z1Er9tJyOPMeTM272561	rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606	intact-crc:1AD5047F5C386BDB|rigid:lATlSScRobTKDWyAYNIAoUfyM5k	false	strep tag:c-c|binding-associated region:212-363	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84198	uniprotkb:Q9Y5J9	intact:EBI-22302615	intact:EBI-1049085|uniprotkb:Q3KQS9|uniprotkb:Q9UN04|uniprotkb:B0YJA5|ensembl:ENSP00000422122.2	psi-mi:o84198_chltr(display_long)|uniprotkb:CT_195(locus name)	psi-mi:tim8b_human(display_long)|uniprotkb:Deafness dystonia protein 2(gene name synonym)|uniprotkb:DDP-like protein(gene name synonym)|uniprotkb:TIM8B(gene name synonym)|uniprotkb:TIMM8B(gene name)|psi-mi:TIMM8B(display_short)|uniprotkb:DDP2(gene name synonym)|uniprotkb:DDPL(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302622|imex:IM-27647-85	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219699.1|refseq:WP_010725118.1|mint:O84198"	"refseq:NP_036591.2|ensembl:ENSG00000150779.12(gene)|ensembl:ENST00000504148.3(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042719""(mitochondrial intermembrane space protein transporter complex)|go:""GO:0045039""(protein insertion into mitochondrial inner membrane)|go:""GO:0140318""(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|mint:Q9Y5J9|reactome:R-HSA-1268020|panther:PTHR19338(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:j0Kp4k//hsLl+Z1Er9tJyOPMeTM272561	rogid:7DK/1BIkwyl9KMIgEFWqRhZn2ZE9606	intact-crc:1AD5047F5C386BDB|rigid:lATlSScRobTKDWyAYNIAoUfyM5k	false	strep tag:c-c|binding-associated region:212-363	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84225	uniprotkb:Q8IWV8	intact:EBI-22302631	intact:EBI-1237260|uniprotkb:O15057|uniprotkb:Q4VXK2|uniprotkb:Q5TFH6|uniprotkb:Q6P2I2|uniprotkb:Q6ZUD0|ensembl:ENSP00000361990.1	psi-mi:o84225_chltr(display_long)|uniprotkb:CT_222(locus name)	psi-mi:ubr2_human(display_long)|uniprotkb:UBR2(gene name)|psi-mi:UBR2(display_short)|uniprotkb:C6orf133(gene name synonym)|uniprotkb:KIAA0349(gene name synonym)|uniprotkb:N-recognin-2(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-2(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-II(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302636|imex:IM-27647-63	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|mint:O84225"	"refseq:NP_001171730.1|refseq:NP_056070.1|refseq:XP_005249022.1|ensembl:ENSG00000024048.11(gene)|ensembl:ENST00000372899.6(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007131""(reciprocal meiotic recombination)|go:""GO:0007140""(male meiotic nuclear division)|go:""GO:0007141""(male meiosis I)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010526""(transposable element silencing)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070728""(L-leucine binding)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:0071596""(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:""GO:0141053""(histone H2A ubiquitin ligase activity)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR003769(Adaptor protein ClpS, core)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR036390|interpro:IPR039164|interpro:IPR042065|interpro:IPR044046|interpro:IPR047508|interpro:IPR055194|mint:Q8IWV8|rcsb pdb:3NY2|rcsb pdb:3NY3|rcsb pdb:5TDA|rcsb pdb:5TDB|rcsb pdb:5TDD|rcsb pdb:5UM3|reactome:R-HSA-983168|dip:DIP-38165N|panther:PTHR21497(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/28	rogid:/d4W43RkW9aL5Doe4hdOflMCD88272561	rogid:FhRNI+FmJXWFjMAY1EUCiwqZPGY9606	intact-crc:0FE5D53F45529412|rigid:qCw4WbtSlzAQMXFLdo8slFFXqzc	false	strep tag:c-c|binding-associated region:89-129	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84225	uniprotkb:Q71F23	intact:EBI-22302631	intact:EBI-2515234|uniprotkb:Q09GN2|uniprotkb:Q32Q71|uniprotkb:A2RRD9|uniprotkb:Q9H5G1|ensembl:ENSP00000281453.5	psi-mi:o84225_chltr(display_long)|uniprotkb:CT_222(locus name)	psi-mi:cenpu_human(display_long)|uniprotkb:CENPU(gene name)|psi-mi:CENPU(display_short)|uniprotkb:Centromere protein of 50 kDa(gene name synonym)|uniprotkb:ICEN24(gene name synonym)|uniprotkb:Interphase centromere complex protein 24(gene name synonym)|uniprotkb:KLIP1(gene name synonym)|uniprotkb:KSHV latent nuclear antigen-interacting protein 1(gene name synonym)|uniprotkb:MLF1-interacting protein(gene name synonym)|uniprotkb:MLF1IP(gene name synonym)|uniprotkb:PBIP1(gene name synonym)|uniprotkb:Polo-box-interacting protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302636|imex:IM-27647-63	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|mint:O84225"	"refseq:NP_078905.2|ensembl:ENSG00000151725.12(gene)|ensembl:ENST00000281453.10(transcript)|go:""GO:0000939""(inner kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007059""(chromosome segregation)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043009""(chordate embryonic development)|interpro:IPR025214|mint:Q71F23|rcsb pdb:7PB8|rcsb pdb:7PKN|rcsb pdb:7QOO|rcsb pdb:7R5S|rcsb pdb:7R5V|rcsb pdb:7XHN|rcsb pdb:7XHO|rcsb pdb:7YWX|rcsb pdb:7YYH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-48539N|panther:PTHR32222(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/28	rogid:/d4W43RkW9aL5Doe4hdOflMCD88272561	rogid:9FtaN8LMgqRrTXtmbt5NDbKCyus9606	intact-crc:0FE5D53F45529412|rigid:qCw4WbtSlzAQMXFLdo8slFFXqzc	false	strep tag:c-c|binding-associated region:89-129	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84225	uniprotkb:Q8IWV7	intact:EBI-22302631	intact:EBI-711736|ensembl:ENSP00000290650.4|uniprotkb:O60708|uniprotkb:O75492|uniprotkb:Q14D45|uniprotkb:Q68DN9|uniprotkb:Q8IWY6|uniprotkb:Q96JY4	psi-mi:o84225_chltr(display_long)|uniprotkb:CT_222(locus name)	psi-mi:ubr1_human(display_long)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-I(gene name synonym)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302636|imex:IM-27647-63	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|mint:O84225"	"ensembl:ENSG00000159459.12(gene)|ensembl:ENST00000290650.9(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000502""(proteasome complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070728""(L-leucine binding)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:0071596""(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR003769(Adaptor protein ClpS, core)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR036390|interpro:IPR039164|interpro:IPR042065|interpro:IPR044046|interpro:IPR047507|interpro:IPR055194|mint:Q8IWV7|rcsb pdb:3NY1|rcsb pdb:5TDC|reactome:R-HSA-983168|refseq:NP_777576.1|efo:""Orphanet:2315""|dip:DIP-47033N|panther:PTHR21497(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/28	rogid:/d4W43RkW9aL5Doe4hdOflMCD88272561	rogid:BcTsfaVfIa+WpIb8EPaPca2UZN89606	intact-crc:0FE5D53F45529412|rigid:qCw4WbtSlzAQMXFLdo8slFFXqzc	false	strep tag:c-c|binding-associated region:89-129	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84226	uniprotkb:Q9P2E9	intact:EBI-22302645	intact:EBI-2371806|uniprotkb:A2A2S6|uniprotkb:A6NCN6|uniprotkb:O75300|uniprotkb:O75301|uniprotkb:Q5W165|uniprotkb:Q96SB2|uniprotkb:Q9BWP1|uniprotkb:Q9H476|uniprotkb:A0A0A0MRV0|ensembl:ENSP00000246043.4|ensembl:ENSP00000367044.1|intact:EBI-28985482	psi-mi:o84226_chltr(display_long)|uniprotkb:CT_223(locus name)	psi-mi:rrbp1_human(display_long)|uniprotkb:RRBP1(gene name)|psi-mi:RRBP1(display_short)|uniprotkb:KIAA1398(gene name synonym)|uniprotkb:Ribosome receptor protein(gene name synonym)|uniprotkb:180 kDa ribosome receptor homolog(gene name synonym)|uniprotkb:ES/130-related protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302652|imex:IM-27647-87	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219728.1|refseq:WP_010725128.1|mint:O84226"	"refseq:NP_001036041.1|refseq:NP_004578.2|ensembl:ENSG00000125844.17(gene)|ensembl:ENST00000246043.8(transcript)|ensembl:ENST00000377813.6(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005840""(ribosome)|go:""GO:0006412""(translation)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR040248|mint:Q9P2E9|reactome:R-HSA-9725370|panther:PTHR18939(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/28	rogid:cwfEeY7cDtx5J6pOS7Zz2bvqypM272561	rogid:uOiVzIAM5bsSl2s1BSIfnUtZ3Ms9606	intact-crc:500EF8363F2BA9D5|rigid:L/xuBJ88nYHdu/gTJoKSSLmQh7M	false	strep tag:c-c|binding-associated region:84-270	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84226	uniprotkb:Q9Y678	intact:EBI-22302645	intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002.6	psi-mi:o84226_chltr(display_long)|uniprotkb:CT_223(locus name)	psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302652|imex:IM-27647-87	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219728.1|refseq:WP_010725128.1|mint:O84226"	"refseq:NP_057212.1|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|ensembl:ENSG00000181789.14(gene)|ensembl:ENST00000314797.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0009306""(protein secretion)|go:""GO:0030126""(COPI vesicle coat)|go:""GO:0030133""(transport vesicle)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0072384""(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N|panther:PTHR10261(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/28	rogid:cwfEeY7cDtx5J6pOS7Zz2bvqypM272561	rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606	intact-crc:500EF8363F2BA9D5|rigid:L/xuBJ88nYHdu/gTJoKSSLmQh7M	false	strep tag:c-c|binding-associated region:84-270	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84226	uniprotkb:Q14677	intact:EBI-22302645	intact:EBI-1171113|uniprotkb:Q8NAF1|uniprotkb:Q96E05|uniprotkb:D3DQJ6|uniprotkb:B7Z6F8|intact:EBI-28971708|ensembl:ENSP00000388340.2	psi-mi:o84226_chltr(display_long)|uniprotkb:CT_223(locus name)	psi-mi:epn4_human(display_long)|uniprotkb:CLINT1(gene name)|psi-mi:CLINT1(display_short)|uniprotkb:ENTH(gene name synonym)|uniprotkb:EPN4(gene name synonym)|uniprotkb:EPNR(gene name synonym)|uniprotkb:KIAA0171(gene name synonym)|uniprotkb:Epsin-4(gene name synonym)|uniprotkb:Epsin-related protein(gene name synonym)|uniprotkb:Enthoprotin(gene name synonym)|uniprotkb:Clathrin-interacting protein localized in the trans-Golgi region(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302652|imex:IM-27647-87	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219728.1|refseq:WP_010725128.1|mint:O84226"	"refseq:NP_001182484.1|refseq:NP_001182485.1|refseq:NP_055481.1|panther:PTHR12276(orthology-group)|dip:DIP-45604N|ensembl:ENSG00000113282.14(gene)|ensembl:ENST00000411809.7(transcript)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0016020""(membrane)|go:""GO:0030125""(clathrin vesicle coat)|go:""GO:0030276""(clathrin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q14677|rcsb pdb:1XGW|rcsb pdb:2QY7|rcsb pdb:2V8S|reactome:R-HSA-432722"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/28	rogid:cwfEeY7cDtx5J6pOS7Zz2bvqypM272561	rogid:cflzNAWnEQR6zTr4d+hwfy1doC49606	intact-crc:500EF8363F2BA9D5|rigid:L/xuBJ88nYHdu/gTJoKSSLmQh7M	false	strep tag:c-c|binding-associated region:84-270	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:Q9H3G5	uniprotkb:O84227	intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|intact:EBI-1058665|uniprotkb:A4D1A4|ensembl:ENSP00000265394.5|ensembl:ENSP00000379572.3|ensembl:ENSP00000387164.1	intact:EBI-22302662	psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym)	psi-mi:o84227_chltr(display_long)|uniprotkb:CT_224(locus name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272561(chltr)|taxid:272561(chltr)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302669|imex:IM-27647-47	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_061902.2|refseq:NP_112601.3|ensembl:ENSG00000106066.15(gene)|ensembl:ENST00000265394.10(transcript)|ensembl:ENST00000396276.7(transcript)|ensembl:ENST00000409850.5(transcript)|go:""GO:0004185""(serine-type carboxypeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1|panther:PTHR11802(orthology-group)"	"go:""GO:0016020""(membrane)|refseq:NP_219729.1|refseq:WP_009873078.1|mint:O84227"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:antgab61u6D+KmbopQeowXqSqWQ9606	rogid:p1+tQrS/4/mC6+KIi6kLelc2MAo272561	intact-crc:86377C0CE9913F0B|rigid:6AguGKRRy/plXnvk1OZ1fsKQJZ4	false	-	binding-associated region:84-147|strep tag:c-c	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84229	uniprotkb:Q13045	intact:EBI-22302680	intact:EBI-351549|uniprotkb:B4DIL0|uniprotkb:F5H407|uniprotkb:J3QLG3|ensembl:ENSP00000324573.4|ensembl:ENSP00000491480.1	psi-mi:o84229_chltr(display_long)|uniprotkb:CT_226(locus name)	psi-mi:flii_human(display_long)|uniprotkb:FLII(gene name)|psi-mi:FLII(display_short)|uniprotkb:FLIL(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302687|imex:IM-27647-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219731.1|refseq:WP_010725129.1|mint:O84229"	"efo:""Orphanet:819""|ensembl:ENSG00000177731.16(gene)|ensembl:ENSG00000284571.3(gene)|ensembl:ENST00000327031.9(transcript)|ensembl:ENST00000638207.2(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003779""(actin binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0005925""(focal adhesion)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030239""(myofibril assembly)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042995""(cell projection)|go:""GO:0045214""(sarcomere organization)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR025875|interpro:IPR029006|interpro:IPR032675|mint:Q13045|refseq:NP_001243193.1|refseq:NP_001243194.1|refseq:NP_002009.1|panther:PTHR11977(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:H7GYv0eZQr/CnxlDvp7PBXZkd+k272561	rogid:hzls0Ir+lr0+wNsTUeIURV3fXVQ9606	intact-crc:1A0A356E5866DDED|rigid:WBtuxKE8hconGkNe4fVANgNpYxQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84229	uniprotkb:Q32MZ4	intact:EBI-22302680	intact:EBI-1369100|uniprotkb:O75766|uniprotkb:O75799|uniprotkb:Q32MZ5|uniprotkb:Q53T49|uniprotkb:Q6PKG2|uniprotkb:E9PGZ2|uniprotkb:Q9Y607|ensembl:ENSP00000375857.4|intact:EBI-28987401	psi-mi:o84229_chltr(display_long)|uniprotkb:CT_226(locus name)	psi-mi:lrrf1_human(display_long)|uniprotkb:LRRFIP1(gene name)|psi-mi:LRRFIP1(display_short)|uniprotkb:GCF2(gene name synonym)|uniprotkb:TRIP(gene name synonym)|uniprotkb:TAR RNA-interacting protein(gene name synonym)|uniprotkb:GC-binding factor 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302687|imex:IM-27647-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219731.1|refseq:WP_010725129.1|mint:O84229"	"refseq:NP_001131024.1|refseq:NP_001131025.1|refseq:NP_004726.2|refseq:NP_001131022.1|ensembl:ENSG00000124831.20(gene)|ensembl:ENST00000392000.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|interpro:IPR019139|mint:Q32MZ4|rcsb pdb:4H22|reactome:R-HSA-1839117|reactome:R-HSA-3134973|reactome:R-HSA-5655302|panther:PTHR19212(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:H7GYv0eZQr/CnxlDvp7PBXZkd+k272561	rogid:GRBGUu5k+BNhFDb4Z2B2XkQ0mcQ9606	intact-crc:1A0A356E5866DDED|rigid:WBtuxKE8hconGkNe4fVANgNpYxQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84229	uniprotkb:Q9NYL9	intact:EBI-22302680	intact:EBI-352614|uniprotkb:Q9NT43|uniprotkb:Q9NZR0|uniprotkb:B2R6G7|ensembl:ENSP00000308753.7	psi-mi:o84229_chltr(display_long)|uniprotkb:CT_226(locus name)	psi-mi:tmod3_human(display_long)|uniprotkb:TMOD3(gene name)|psi-mi:TMOD3(display_short)|uniprotkb:Ubiquitous tropomodulin(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302687|imex:IM-27647-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219731.1|refseq:WP_010725129.1|mint:O84229"	"refseq:NP_055362.1|ensembl:ENSG00000138594.14(gene)|ensembl:ENST00000308580.12(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005523""(tropomyosin binding)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005865""(striated muscle thin filament)|go:""GO:0005912""(adherens junction)|go:""GO:0006936""(muscle contraction)|go:""GO:0007015""(actin filament organization)|go:""GO:0030016""(myofibril)|go:""GO:0030239""(myofibril assembly)|go:""GO:0044772""(mitotic cell cycle phase transition)|go:""GO:0048821""(erythrocyte development)|go:""GO:0051694""(pointed-end actin filament capping)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:1901992""(positive regulation of mitotic cell cycle phase transition)|interpro:IPR004934(Tropomodulin)|interpro:IPR032675|mint:Q9NYL9|reactome:R-HSA-390522|reactome:R-HSA-9013418|reactome:R-HSA-9696264|refseq:XP_016877576.1|refseq:XP_016877577.1|panther:PTHR10901(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:H7GYv0eZQr/CnxlDvp7PBXZkd+k272561	rogid:crEfCAAepSPAE8ByBpD4Sr14P5I9606	intact-crc:1A0A356E5866DDED|rigid:WBtuxKE8hconGkNe4fVANgNpYxQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84229	uniprotkb:Q9Y608	intact:EBI-22302680	intact:EBI-1023718|uniprotkb:Q68CV3|uniprotkb:Q9NXH5|uniprotkb:A8K649|uniprotkb:A8MXR0|uniprotkb:B4DY63|ensembl:ENSP00000338727.4	psi-mi:o84229_chltr(display_long)|uniprotkb:CT_226(locus name)	psi-mi:lrrf2_human(display_long)|uniprotkb:LRRFIP2(gene name)|psi-mi:LRRFIP2(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302687|imex:IM-27647-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219731.1|refseq:WP_010725129.1|mint:O84229"	"refseq:XP_011532519.1|refseq:XP_011532520.1|refseq:XP_011532521.1|refseq:XP_005265596.1|refseq:XP_005265597.1|refseq:NP_001335239.1|refseq:NP_001335240.1|refseq:NP_006300.1|refseq:NP_060194.1|refseq:NP_001127841.1|refseq:NP_001269620.1|refseq:XP_016862973.1|ensembl:ENSG00000093167.18(gene)|ensembl:ENST00000336686.9(transcript)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030275""(LRR domain binding)|interpro:IPR019139|mint:Q9Y608|panther:PTHR19212(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:H7GYv0eZQr/CnxlDvp7PBXZkd+k272561	rogid:ma/crL7UY91uJ8bqLfkX3K8aQLI9606	intact-crc:1A0A356E5866DDED|rigid:WBtuxKE8hconGkNe4fVANgNpYxQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84230	uniprotkb:Q9NVW2	intact:EBI-22302695	intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|ensembl:ENSP00000253571.3|ensembl:ENSP00000328059.6|uniprotkb:B2RBQ1	psi-mi:o84230_chltr(display_long)|uniprotkb:CT_227(locus name)	psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302702|imex:IM-27647-21	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219732.1|refseq:WP_009871574.1|mint:O84230"	"ensembl:ENSG00000131263.13(gene)|ensembl:ENST00000332687.11(transcript)|ensembl:ENST00000349225.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR051834|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168|refseq:NP_057204.2|refseq:NP_899196.1|panther:PTHR45931(orthology-group)|efo:""Orphanet:528084"""	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:zp/rtaPMi1WqXCfsRhEh33c+1b4272561	rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606	intact-crc:F41D1C534E0F9769|rigid:jfl/UL+8rniRM80iuTBkx6BxC1k	false	binding-associated region:87-132|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84231	uniprotkb:O14974	intact:EBI-22302709	intact:EBI-351726|uniprotkb:Q2NKL4|uniprotkb:Q569H0|uniprotkb:Q86WU3|uniprotkb:Q8NFR6|uniprotkb:Q9BYH0|intact:EBI-28988491|uniprotkb:B4DZ09|uniprotkb:F8VWB4|ensembl:ENSP00000261207.5|ensembl:ENSP00000389168.2	psi-mi:o84231_chltr(display_long)|uniprotkb:CT_228(locus name)	psi-mi:mypt1_human(display_long)|uniprotkb:PPP1R12A(gene name)|psi-mi:PPP1R12A(display_short)|uniprotkb:MBS(gene name synonym)|uniprotkb:MYPT1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302716|imex:IM-27647-65	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219733.1|refseq:WP_009873080.1|mint:O84231"	"refseq:NP_001137357.1|refseq:NP_001137358.1|refseq:NP_002471.1|refseq:NP_001231919.1|refseq:NP_001231921.1|refseq:XP_011536685.1|ensembl:ENSG00000058272.19(gene)|ensembl:ENST00000261207.9(transcript)|ensembl:ENST00000450142.7(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0001725""(stress fiber)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0017020""(myosin phosphatase regulator activity)|go:""GO:0019208""(phosphatase regulator activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0031672""(A band)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043292""(contractile muscle fiber)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046822""(regulation of nucleocytoplasmic transport)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR031775|interpro:IPR036770|interpro:IPR051226|mint:O14974|rcsb pdb:2KJY|rcsb pdb:5HUZ|reactome:R-HSA-2565942|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|dip:DIP-33186N|panther:PTHR24179(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/26	rogid:DZj7bSZEXikp0OeSEhXdXMzjssU272561	rogid:Xi5lGskc0tWQCHtbYlgR45ERMSk9606	intact-crc:52E9409FC9C50F27|rigid:oB0ZMsHXnaEyt4jlGsCLxcRU0t8	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84231	uniprotkb:Q53HC5	intact:EBI-22302709	intact:EBI-724915|uniprotkb:Q8TAP0|uniprotkb:Q9NUX3|ensembl:ENSP00000300976.3	psi-mi:o84231_chltr(display_long)|uniprotkb:CT_228(locus name)	psi-mi:klh26_human(display_long)|uniprotkb:KLHL26(gene name)|psi-mi:KLHL26(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302722|imex:IM-27647-3	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219733.1|refseq:WP_009873080.1|mint:O84231"	refseq:NP_060786.1|ensembl:ENSG00000167487.12(gene)|ensembl:ENST00000300976.9(transcript)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030588|mint:Q53HC5|panther:PTHR45632(orthology-group)	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:DZj7bSZEXikp0OeSEhXdXMzjssU272561	rogid:ttSomgoE7proVj7jmp9Umc/IbXk9606	intact-crc:26782E88A510AA86|rigid:EwCpvedmmc3knXWASh5vKEgnRyE	false	strep tag:c-c|binding-associated region:88-196	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84231	uniprotkb:P35221	intact:EBI-22302709	intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669.7	psi-mi:o84231_chltr(display_long)|uniprotkb:CT_228(locus name)	psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302722|imex:IM-27647-3	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219733.1|refseq:WP_009873080.1|mint:O84231"	"ensembl:ENSG00000044115.21(gene)|ensembl:ENST00000302763.12(transcript)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007406""(negative regulation of neuroblast proliferation)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008104""(protein localization)|go:""GO:0008584""(male gonad development)|go:""GO:0014704""(intercalated disc)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016264""(gap junction assembly)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0016600""(flotillin complex)|go:""GO:0017166""(vinculin binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0031103""(axon regeneration)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043297""(apical junction assembly)|go:""GO:0043627""(response to estrogen)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045880""(positive regulation of smoothened signaling pathway)|go:""GO:0051015""(actin filament binding)|go:""GO:0071681""(cellular response to indole-3-methanol)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:2000146""(negative regulation of cell motility)|go:""GO:2001045""(negative regulation of integrin-mediated signaling pathway)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:2001241""(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:7UTJ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467|reactome:R-HSA-9762292|reactome:R-HSA-9764302|reactome:R-HSA-9833576|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|refseq:NP_001894.2|efo:""Orphanet:26106""|efo:""Orphanet:99001""|dip:DIP-515N|panther:PTHR18914(orthology-group)|ensembl:ENSP00000304669.7|ensembl:ENST00000540387.5|ensembl:ENSP00000438476.1"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:DZj7bSZEXikp0OeSEhXdXMzjssU272561	rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606	intact-crc:26782E88A510AA86|rigid:EwCpvedmmc3knXWASh5vKEgnRyE	false	strep tag:c-c|binding-associated region:88-196	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:O43819	intact:EBI-22302746	intact:EBI-357012|uniprotkb:Q3T1B5|uniprotkb:Q9UK87|ensembl:ENSP00000252785.3|ensembl:ENSP00000379046.4|ensembl:ENSP00000444242.1|ensembl:ENSP00000444433.1	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	psi-mi:sco2_human(display_long)|uniprotkb:SCO2(gene name)|psi-mi:SCO2(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302731|imex:IM-27647-67	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"efo:""Orphanet:1561""|efo:""Orphanet:521411""|efo:""Orphanet:98619""|panther:PTHR12151(orthology-group)|ensembl:ENSG00000284194.3(gene)|ensembl:ENST00000252785.3(transcript)|ensembl:ENST00000395693.8(transcript)|ensembl:ENST00000535425.5(transcript)|ensembl:ENST00000543927.6(transcript)|go:""GO:0001654""(eye development)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003012""(muscle system process)|go:""GO:0005507""(copper ion binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0014823""(response to activity)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0016531""(copper chaperone activity)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0030016""(myofibril)|go:""GO:0033617""(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|mint:O43819|rcsb pdb:2RLI|reactome:R-HSA-5628897|reactome:R-HSA-9864848|refseq:NP_001162580.1|refseq:NP_001162581.1|refseq:NP_001162582.1|refseq:NP_005129.2|dip:DIP-46088N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:RaD9DPaOnFKJvwNRUK9KQdptmqc9606	intact-crc:C08FFAF127C2049A|rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw	false	strep tag:c-c|binding-associated region:93-215	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:Q9BRT9	intact:EBI-22302746	intact:EBI-747500|uniprotkb:Q8N648|ensembl:ENSP00000276533.3|ensembl:ENSP00000428754.1|uniprotkb:B2R8H5|uniprotkb:D3DSY0	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	psi-mi:sld5_human(display_long)|uniprotkb:SLD5(gene name synonym)|uniprotkb:GINS complex subunit 4(gene name synonym)|uniprotkb:GINS4(gene name)|psi-mi:GINS4(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302731|imex:IM-27647-67	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"refseq:NP_115712.1|refseq:XP_005273716.1|ensembl:ENSG00000147536.12(gene)|ensembl:ENST00000276533.4(transcript)|ensembl:ENST00000518671.5(transcript)|go:""GO:0000727""(double-strand break repair via break-induced replication)|go:""GO:0000811""(GINS complex)|go:""GO:0001833""(inner cell mass cell proliferation)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0071162""(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|mint:Q9BRT9|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:8B9D|rcsb pdb:8OK2|reactome:R-HSA-176974|dip:DIP-29334N|panther:PTHR21206(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:DL/sJVWAbcV57zkjNgnsQ5acRi09606	intact-crc:C08FFAF127C2049A|rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw	false	strep tag:c-c|binding-associated region:93-215	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:Q9BRX5	intact:EBI-22302746	intact:EBI-2857315|uniprotkb:B2RDP3|uniprotkb:Q9H870|uniprotkb:E9PB21|ensembl:ENSP00000318196.6	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	psi-mi:psf3_human(display_long)|uniprotkb:GINS3(gene name)|psi-mi:GINS3(display_short)|uniprotkb:PSF3(gene name synonym)|uniprotkb:GINS complex subunit 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302731|imex:IM-27647-67	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"refseq:NP_001119601.1|refseq:NP_001119602.1|refseq:NP_073607.2|ensembl:ENSG00000181938.14(gene)|ensembl:ENST00000318129.6(transcript)|go:""GO:0000811""(GINS complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0071162""(CMG complex)|go:""GO:1902975""(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|interpro:IPR055221|mint:Q9BRX5|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:8B9D|rcsb pdb:8OK2|reactome:R-HSA-176974|dip:DIP-29333N|panther:PTHR22768(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:3anXwRLIwu/t1G1v+P1yzhh7QqA9606	intact-crc:C08FFAF127C2049A|rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw	false	strep tag:c-c|binding-associated region:93-215	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:Q9Y248	intact:EBI-22302746	intact:EBI-747491|uniprotkb:Q6IAG9|ensembl:ENSP00000253462.3|uniprotkb:D3DUM5	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	psi-mi:psf2_human(display_long)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:GINS2(gene name)|psi-mi:GINS2(display_short)|uniprotkb:CGI-122(orf name)|uniprotkb:DC5(orf name)|uniprotkb:HSPC037(orf name)|uniprotkb:PSF2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302731|imex:IM-27647-67	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"refseq:NP_057179.1|ensembl:ENSG00000131153.9(gene)|ensembl:ENST00000253462.8(transcript)|go:""GO:0000727""(double-strand break repair via break-induced replication)|go:""GO:0000811""(GINS complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0071162""(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|mint:Q9Y248|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:8B9D|rcsb pdb:8OK2|reactome:R-HSA-176974|dip:DIP-29332N|panther:PTHR12772(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:OKFZLWhkmZNQxqS2tKptq61jsxs9606	intact-crc:C08FFAF127C2049A|rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw	false	strep tag:c-c|binding-associated region:93-215	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:P52294	intact:EBI-22302746	intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|uniprotkb:D3DN93|ensembl:ENSP00000343701.6	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302731|imex:IM-27647-67	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"panther:PTHR23316(orthology-group)|refseq:NP_002255.3|ensembl:ENSG00000114030.13(gene)|ensembl:ENST00000344337.11(transcript)|go:""GO:0000018""(regulation of DNA recombination)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0014069""(postsynaptic density)|go:""GO:0014841""(skeletal muscle satellite cell proliferation)|go:""GO:0014901""(satellite cell activation involved in skeletal muscle regeneration)|go:""GO:0030425""(dendrite)|go:""GO:0042564""(NLS-dependent protein nuclear import complex)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-68616|reactome:R-HSA-909733|reactome:R-HSA-9636249|refseq:XP_005247494.1|dip:DIP-29296N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606	intact-crc:C08FFAF127C2049A|rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw	false	strep tag:c-c|binding-associated region:93-215	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:Q14691	intact:EBI-22302746	intact:EBI-9019496|uniprotkb:Q9NQI7|uniprotkb:Q9NQE2|ensembl:ENSP00000262460.4|ensembl:ENSP00000512943.1	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	psi-mi:psf1_human(display_long)|uniprotkb:GINS1(gene name)|psi-mi:GINS1(display_short)|uniprotkb:GINS complex subunit 1(gene name synonym)|uniprotkb:KIAA0186(gene name synonym)|uniprotkb:PSF1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302731|imex:IM-27647-67	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"dip:DIP-29331N|ensembl:ENSG00000101003.12(gene)|ensembl:ENST00000262460.5(transcript)|ensembl:ENST00000696874.1(transcript)|go:""GO:0000811""(GINS complex)|go:""GO:0001833""(inner cell mass cell proliferation)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0071162""(CMG complex)|go:""GO:1902983""(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|mint:Q14691|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:8B9D|rcsb pdb:8OK2|reactome:R-HSA-176974|refseq:NP_066545.3|panther:PTHR12914(orthology-group)|efo:""Orphanet:505227"""	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:uUjKx4tV7oRDtXaL9zDlBBQDRjQ9606	intact-crc:C08FFAF127C2049A|rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw	false	strep tag:c-c|binding-associated region:93-215	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:Q9H9L3	intact:EBI-22302746	intact:EBI-751335|uniprotkb:Q64KA2|uniprotkb:D3DVC6|ensembl:ENSP00000323424.6|ensembl:ENSP00000357202.2	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	psi-mi:i20l2_human(display_long)|uniprotkb:ISG20L2(gene name)|psi-mi:ISG20L2(display_short)|uniprotkb:HSD38(orf name)|uniprotkb:HSD-38(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302731|imex:IM-27647-67	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"refseq:NP_001290024.1|refseq:XP_005245573.1|refseq:XP_006711623.1|refseq:XP_006711624.1|ensembl:ENSG00000143319.18(gene)|ensembl:ENST00000313146.11(transcript)|ensembl:ENST00000368219.2(transcript)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004527""(exonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0006396""(RNA processing)|go:""GO:0042254""(ribosome biogenesis)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036397|interpro:IPR037433|interpro:IPR047021|mint:Q9H9L3|rcsb pdb:7YW5|reactome:R-HSA-6791226|panther:PTHR12801(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:i/TZBz8UuJIRm7WZZKjHYU75AS89606	intact-crc:C08FFAF127C2049A|rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw	false	strep tag:c-c|binding-associated region:93-215	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:Q9UNQ2	intact:EBI-22302746	intact:EBI-395738|uniprotkb:O76025|uniprotkb:Q9BU77|uniprotkb:Q9UES1|ensembl:ENSP00000199320.4	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	"psi-mi:dim1_human(display_long)|uniprotkb:DIMT1L(gene name synonym)|uniprotkb:DIM1 dimethyladenosine transferase 1 homolog(gene name synonym)|uniprotkb:DIM1 dimethyladenosine transferase 1-like(gene name synonym)|uniprotkb:DIMT1(gene name)|psi-mi:DIMT1(display_short)|uniprotkb:""18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase""(gene name synonym)|uniprotkb:18S rRNA dimethylase(gene name synonym)|uniprotkb:""S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase""(gene name synonym)|uniprotkb:HUSSY-05(orf name)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302731|imex:IM-27647-67	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"rcsb pdb:6W6C|ensembl:ENSG00000086189.11(gene)|ensembl:ENST00000199320.9(transcript)|go:""GO:0000179""(""rRNA (adenine-N6,N6-)-dimethyltransferase activity"")|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0031167""(rRNA methylation)|go:""GO:0032040""(small-subunit processome)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0052909""(""18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity"")|go:""GO:2000234""(positive regulation of rRNA processing)|interpro:IPR001737(Ribosomal RNA adenine methylase transferase)|interpro:IPR011530(rRNA adenine dimethylase)|interpro:IPR020596|interpro:IPR020598|interpro:IPR029063|mint:Q9UNQ2|rcsb pdb:1ZQ9|rcsb pdb:6W6F|rcsb pdb:7MQA|rcsb pdb:7WTS|reactome:R-HSA-6790901|refseq:NP_001335005.1|refseq:NP_055288.1|panther:PTHR11727(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:hx0FRrx+XTeoziOqfesiw4KL+wo9606	intact-crc:C08FFAF127C2049A|rigid:8Q/SbwNlUZN9yoJsTbqUdb88ndw	false	strep tag:c-c|binding-associated region:93-215	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:P62820	intact:EBI-22302746	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302753|imex:IM-27647-5	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:41EF72293B37FF64|rigid:5HMDEJrYjkYgve+IpHzkWTi0c/Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:Q15286	intact:EBI-22302746	intact:EBI-722275|uniprotkb:B4E390|uniprotkb:B2R6E0|ensembl:ENSP00000229340.5	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	psi-mi:rab35_human(display_long)|uniprotkb:Ras-related protein Rab-1C(gene name synonym)|uniprotkb:GTP-binding protein RAY(gene name synonym)|uniprotkb:RAB35(gene name)|psi-mi:RAB35(display_short)|uniprotkb:RAB1C(gene name synonym)|uniprotkb:RAY(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302753|imex:IM-27647-5	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"refseq:NP_001161078.1|refseq:NP_006852.1|ensembl:ENSG00000111737.12(gene)|ensembl:ENST00000229340.10(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0008104""(protein localization)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0019003""(GDP binding)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031175""(neuron projection development)|go:""GO:0031253""(cell projection membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032482""(Rab protein signal transduction)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042470""(melanosome)|go:""GO:0045171""(intercellular bridge)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041815|interpro:IPR050227|mint:Q15286|rcsb pdb:3TW8|rcsb pdb:6EKK|rcsb pdb:6IF2|rcsb pdb:6IF3|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR47977(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:95pH+DyDjv9FcxFeMmGYoJ0KyPo9606	intact-crc:41EF72293B37FF64|rigid:5HMDEJrYjkYgve+IpHzkWTi0c/Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84232	uniprotkb:Q9H0U4	intact:EBI-22302746	intact:EBI-1045214|uniprotkb:A8K7S1|ensembl:ENSP00000310226.6	psi-mi:o84232_chltr(display_long)|uniprotkb:CT_229(locus name)	psi-mi:rab1b_human(display_long)|uniprotkb:RAB1B(gene name)|psi-mi:RAB1B(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302753|imex:IM-27647-5	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219734.1|refseq:WP_010725130.1|mint:O84232"	"refseq:NP_112243.1|dip:DIP-42462N|ensembl:ENSG00000174903.16(gene)|ensembl:ENST00000311481.11(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0019068""(virion assembly)|go:""GO:0030133""(transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:Q9H0U4|rcsb pdb:3JZA|rcsb pdb:3NKV|rcsb pdb:4HLQ|rcsb pdb:4I1O|rcsb pdb:5O74|rcsb pdb:5SZH|rcsb pdb:5SZK|rcsb pdb:6SKU|rcsb pdb:8ALK|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:ENmeiCsJQtbxFY+r5Virg9Y/RuQ272561	rogid:EI6DHq7xCboSkoqGY5NmVY4Iqf09606	intact-crc:41EF72293B37FF64|rigid:5HMDEJrYjkYgve+IpHzkWTi0c/Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:P36406	intact:EBI-22302763	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524.9	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302770|imex:IM-27647-89	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|ensembl:ENSG00000113595.15(gene)|ensembl:ENST00000231524.14(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019003""(GDP binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR024156|interpro:IPR027370|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|refseq:XP_016864933.1|panther:PTHR11711(orthology-group)|ensembl:ENSP00000231524.9|ensembl:ENST00000274327.11|ensembl:ENSP00000274327.7|ensembl:ENST00000381018.7|ensembl:ENSP00000370406.3"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	intact-crc:5B16B29A9F885CF5|rigid:HC69XjuDBYPmgu7P+sJwwCqstcE	false	binding-associated region:184-303|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:P28331	intact:EBI-22302763	intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3|ensembl:ENSP00000233190.5|ensembl:ENSP00000399912.1|ensembl:ENSP00000489640.1|ensembl:ENSP00000490898.1	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"efo:""Orphanet:2609""|ensembl:ENSG00000023228.15(gene)|ensembl:ENSG00000283447.3(gene)|ensembl:ENST00000233190.11(transcript)|ensembl:ENST00000449699.5(transcript)|ensembl:ENST00000635748.2(transcript)|ensembl:ENST00000636505.1(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006120""(mitochondrial electron transport, NADH to ubiquinone)|go:""GO:0008137""(""NADH dehydrogenase (ubiquinone) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0009060""(aerobic respiration)|go:""GO:0032981""(mitochondrial respiratory chain complex I assembly)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045271""(respiratory chain complex I)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|interpro:IPR050123|interpro:IPR054351|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9837999|refseq:NP_001186910.1|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186913.1|refseq:NP_004997.4|panther:PTHR11615(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:Q13098	intact:EBI-22302763	intact:EBI-725197|uniprotkb:Q8NA10|uniprotkb:Q9BWL1|ensembl:ENSP00000302873.6	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:csn1_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 1(gene name synonym)|uniprotkb:G protein pathway suppressor 1(gene name synonym)|uniprotkb:Protein MFH(gene name synonym)|uniprotkb:GPS1(gene name)|psi-mi:GPS1(display_short)|uniprotkb:COPS1(gene name synonym)|uniprotkb:CSN1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"refseq:NP_004118.3|refseq:NP_997657.1|refseq:NP_001308021.1|refseq:XP_016880023.1|dip:DIP-42077N|ensembl:ENSG00000169727.14(gene)|ensembl:ENST00000306823.10(transcript)|go:""GO:0000338""(protein deneddylation)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007254""(JNK cascade)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0045116""(protein neddylation)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR019585|interpro:IPR036390|interpro:IPR045135|interpro:IPR048624|mint:Q13098|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:8H38|rcsb pdb:8H3A|rcsb pdb:8H3F|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|panther:PTHR14145(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:OMWZ67qcgKTM0R/hy8L2oCa3cpo9606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:P61201	intact:EBI-22302763	intact:EBI-1050386|uniprotkb:O88950|uniprotkb:Q15647|uniprotkb:Q6FGP4|uniprotkb:Q9BY54|uniprotkb:Q9R249|uniprotkb:Q9UNI2|uniprotkb:Q9UNQ5|ensembl:ENSP00000373553.5	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:csn2_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 15(gene name synonym)|uniprotkb:Alien homolog(gene name synonym)|uniprotkb:COPS2(gene name)|psi-mi:COPS2(display_short)|uniprotkb:CSN2(gene name synonym)|uniprotkb:TRIP15(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"refseq:NP_001137359.1|refseq:NP_004227.1|dip:DIP-42076N|ensembl:ENSG00000166200.15(gene)|ensembl:ENST00000388901.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000338""(protein deneddylation)|go:""GO:0001833""(inner cell mass cell proliferation)|go:""GO:0001834""(trophectodermal cell proliferation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0030182""(neuron differentiation)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0045116""(protein neddylation)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR050871|mint:P61201|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6A73|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:8H38|rcsb pdb:8H3A|rcsb pdb:8H3F|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|panther:PTHR10678(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:MrlEHktIBvvcQux7Z7kqYJYgbbs9606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:Q9UNS2	intact:EBI-22302763	intact:EBI-350590|uniprotkb:O43191|uniprotkb:Q7LDR6|uniprotkb:B2R683|uniprotkb:B4DY81|ensembl:ENSP00000268717.5	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:csn3_human(display_long)|uniprotkb:COPS3(gene name)|psi-mi:COPS3(display_short)|uniprotkb:CSN3(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"refseq:NP_001186054.1|refseq:NP_003644.2|refseq:XP_005256894.1|ensembl:ENSG00000141030.13(gene)|ensembl:ENST00000268717.10(transcript)|go:""GO:0000338""(protein deneddylation)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007165""(signal transduction)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0009416""(response to light stimulus)|go:""GO:0045116""(protein neddylation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:1902162""(obsolete regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR048621|interpro:IPR050756|interpro:IPR055089|mint:Q9UNS2|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:8H38|rcsb pdb:8H3A|rcsb pdb:8H3F|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|refseq:NP_001303283.1|refseq:NP_001303284.1|refseq:NP_001303285.1|refseq:NP_001303286.1|refseq:NP_001303287.1|dip:DIP-32478N|panther:PTHR10758(orthology-group)|ensembl:ENSP00000268717.5|ensembl:ENST00000539941.6|ensembl:ENSP00000437606.2"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:z6E/tPEo/ksVxD5Yyfo89t+ww989606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:Q9BT78	intact:EBI-22302763	intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|uniprotkb:B3KST5|ensembl:ENSP00000264389.2	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"refseq:NP_057213.2|refseq:NP_001244935.1|refseq:NP_001317656.1|dip:DIP-34516N|ensembl:ENSG00000138663.9(gene)|ensembl:ENST00000264389.7(transcript)|go:""GO:0000338""(protein deneddylation)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0016607""(nuclear speck)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0030054""(cell junction)|go:""GO:0045116""(protein neddylation)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR041406|interpro:IPR054559|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:8H38|rcsb pdb:8H3A|rcsb pdb:8H3F|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|panther:PTHR10855(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:O43719	intact:EBI-22302763	intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|ensembl:ENSP00000218364.4|ensembl:ENSP00000442699.1|intact:EBI-28971035	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short)|uniprotkb:HIV Tat-specific factor 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"refseq:NP_001156752.1|refseq:NP_055315.2|ensembl:ENSG00000102241.12(gene)|refseq:XP_005262461.1|rcsb pdb:6Y5Q|rcsb pdb:7EVO|ensembl:ENST00000218364.5(transcript)|ensembl:ENST00000535601.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005684""(U2-type spliceosomal complex)|go:""GO:0005686""(U2 snRNP)|go:""GO:0035861""(site of double-strand break)|go:""GO:0140463""(chromatin-protein adaptor activity)|go:""GO:0160004""(poly-ADP-D-ribose modification-dependent protein binding)|go:""GO:1903241""(U2-type prespliceosome assembly)|go:""GO:1990166""(protein localization to site of double-strand break)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:7Q3L|rcsb pdb:8HK1|reactome:R-HSA-72163|dip:DIP-42095N|panther:PTHR15608(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:PttL+7D+505QAmcHRGNsc40haPY9606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:Q6NUM6	intact:EBI-22302763	intact:EBI-12847032|uniprotkb:A6NG09|uniprotkb:B4DFY2|uniprotkb:Q3KQX2|uniprotkb:A0A087WZB2|ensembl:ENSP00000482502.1	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:tyw1b_human(display_long)|uniprotkb:TYW1B(gene name)|psi-mi:TYW1B(display_short)|uniprotkb:RSAFD2(gene name synonym)|uniprotkb:Radical S-adenosyl methionine and flavodoxin domain-containing protein 2(gene name synonym)|uniprotkb:tRNA wybutosine-synthesizing protein 1 homolog B(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"panther:PTHR13930(orthology-group)|refseq:NP_001138912.2|ensembl:ENSG00000277149.5(gene)|ensembl:ENST00000620995.5(transcript)|go:""GO:0010181""(FMN binding)|go:""GO:0031591""(wybutosine biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0102521""(tRNA-4-demethylwyosine synthase activity)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR007197(Radical SAM)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR013917(Wyosine base formation)|interpro:IPR029039|interpro:IPR034556|mint:Q6NUM6"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:fIFV8S42LjKaRydFyQerBEg/lps9606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:Q9Y4X5	intact:EBI-22302763	intact:EBI-2514233|uniprotkb:Q9UEN0|uniprotkb:Q9H3T6|uniprotkb:O76026|uniprotkb:Q9UP39|uniprotkb:B2R6U3|ensembl:ENSP00000369217.4	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:ari1_human(display_long)|uniprotkb:Protein ariadne-1 homolog(gene name synonym)|uniprotkb:ARIH1(gene name)|psi-mi:ARIH1(display_short)|uniprotkb:ARI(gene name synonym)|uniprotkb:MOP6(gene name synonym)|uniprotkb:UBCH7BP(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-binding protein 1(gene name synonym)|uniprotkb:UbcH7-binding protein(gene name synonym)|uniprotkb:UbcM4-interacting protein(gene name synonym)|uniprotkb:HHARI(gene name synonym)|uniprotkb:H7-AP2(gene name synonym)|uniprotkb:Monocyte protein 6(gene name synonym)|uniprotkb:HUSSY-27(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"ensembl:ENSG00000166233.15(gene)|ensembl:ENST00000379887.9(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0015030""(Cajal body)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0019787""(ubiquitin-like protein transferase activity)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0039585""(PKR/eIFalpha signaling)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0097413""(Lewy body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|interpro:IPR031127|interpro:IPR044066|interpro:IPR045840|interpro:IPR048962|mint:Q9Y4X5|rcsb pdb:1WD2|rcsb pdb:2M9Y|rcsb pdb:4KBL|rcsb pdb:4KC9|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5S|reactome:R-HSA-1169408|reactome:R-HSA-9833110|reactome:R-HSA-9833482|refseq:NP_005735.2|dip:DIP-53626N|panther:PTHR11685(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:4au2wa0c7NccURO3aKdmKN0U3PE9606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:Q9H3P7	intact:EBI-22302763	intact:EBI-1791792|ensembl:ENSP00000355777.5|uniprotkb:Q5VTJ0|uniprotkb:Q6P9F1|uniprotkb:Q8IZC5|uniprotkb:Q8N4D6|uniprotkb:Q9H6U3|uniprotkb:B2RB29	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:gcp60_human(display_long)|uniprotkb:GOCAP1(gene name synonym)|uniprotkb:GOLPH1(gene name synonym)|uniprotkb:ACBD3(gene name)|psi-mi:ACBD3(display_short)|uniprotkb:GCP60(gene name synonym)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"ensembl:ENSG00000182827.9(gene)|ensembl:ENST00000366812.6(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006694""(steroid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR009038(GOLD)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|interpro:IPR036598|interpro:IPR052269|mint:Q9H3P7|rcsb pdb:2N72|rcsb pdb:2N73|rcsb pdb:5LZ1|rcsb pdb:5LZ3|rcsb pdb:5LZ6|rcsb pdb:5TDQ|rcsb pdb:6HLN|rcsb pdb:6HLT|rcsb pdb:6HLV|rcsb pdb:6HLW|rcsb pdb:6HM8|rcsb pdb:6HMV|reactome:R-HSA-432722|refseq:NP_073572.2|dip:DIP-40673N|panther:PTHR22973(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:jAaMXnoXG6RGj+lAgIYk1inXA6o9606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:P13489	intact:EBI-22302763	intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402.2|ensembl:ENSP00000348515.5|ensembl:ENSP00000380729.3|ensembl:ENSP00000380738.1|ensembl:ENSP00000380739.2|ensembl:ENSP00000416589.2|ensembl:ENSP00000433999.1|ensembl:ENSP00000435594.1|ensembl:ENSP00000478664.1|ensembl:ENSP00000479004.1|ensembl:ENSP00000479966.1|ensembl:ENSP00000480036.1|ensembl:ENSP00000484572.1|ensembl:ENSP00000487753.1|ensembl:ENSP00000487940.1|ensembl:ENSP00000488734.1	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|ensembl:ENSG00000023191.17(gene)|ensembl:ENSG00000276230.4(gene)|ensembl:ENST00000354420.7(transcript)|ensembl:ENST00000356187.9(transcript)|ensembl:ENST00000397604.7(transcript)|ensembl:ENST00000397614.5(transcript)|ensembl:ENST00000397615.6(transcript)|ensembl:ENST00000438658.6(transcript)|ensembl:ENST00000533410.5(transcript)|ensembl:ENST00000534797.5(transcript)|ensembl:ENST00000612988.4(transcript)|ensembl:ENST00000617351.4(transcript)|ensembl:ENST00000618184.3(transcript)|ensembl:ENST00000619599.4(transcript)|ensembl:ENST00000621211.2(transcript)|ensembl:ENST00000632527.1(transcript)|ensembl:ENST00000632954.1(transcript)|ensembl:ENST00000633287.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008428""(ribonuclease inhibitor activity)|go:""GO:0016477""(cell migration)|go:""GO:0030027""(lamellipodium)|go:""GO:0032311""(angiogenin-PRI complex)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0036416""(tRNA stabilization)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|interpro:IPR050637|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|refseq:XP_016873595.1|panther:PTHR24112(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:Q92905	intact:EBI-22302763	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512.4	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"ensembl:ENSG00000121022.14(gene)|ensembl:ENST00000357849.9(transcript)|go:""GO:0000338""(protein deneddylation)|go:""GO:0000785""(chromatin)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006412""(translation)|go:""GO:0006508""(proteolysis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0045116""(protein neddylation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046328""(regulation of JNK cascade)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0140492""(metal-dependent deubiquitinase activity)|rcsb pdb:4D18|go:""GO:1903894""(regulation of IRE1-mediated unfolded protein response)|go:""GO:1990182""(exosomal secretion)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR040961|interpro:IPR050242|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:8H38|rcsb pdb:8H3A|rcsb pdb:8H3F|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|refseq:NP_006828.2|dip:DIP-34546N|panther:PTHR10410(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84326	uniprotkb:Q9UBW8	intact:EBI-22302763	intact:EBI-712982|uniprotkb:Q9NVX3|uniprotkb:Q9UJW4|uniprotkb:A8K9A6|ensembl:ENSP00000229251.3|ensembl:ENSP00000438115.1|ensembl:ENSP00000438363.1|ensembl:ENSP00000441852.1|ensembl:ENSP00000446039.1	psi-mi:o84326_chltr(display_long)|uniprotkb:CT_324(locus name)	psi-mi:csn7a_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 7a(gene name synonym)|uniprotkb:Dermal papilla-derived protein 10(gene name synonym)|uniprotkb:COPS7A(gene name)|psi-mi:COPS7A(display_short)|uniprotkb:CSN7A(gene name synonym)|uniprotkb:DERP10(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302779|imex:IM-27647-23	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219829.1|refseq:WP_009871671.1|mint:O84326"	"refseq:NP_001157565.1|refseq:NP_001157566.1|refseq:NP_001157567.1|refseq:NP_057403.1|ensembl:ENSG00000111652.10(gene)|ensembl:ENST00000229251.7(transcript)|ensembl:ENST00000534877.5(transcript)|ensembl:ENST00000534947.5(transcript)|ensembl:ENST00000539735.5(transcript)|ensembl:ENST00000543155.6(transcript)|go:""GO:0000338""(protein deneddylation)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0010387""(COP9 signalosome assembly)|go:""GO:0045116""(protein neddylation)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR041481|interpro:IPR045237|mint:Q9UBW8|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|refseq:XP_005253751.1|dip:DIP-53412N|panther:PTHR15350(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/19	rogid:KoMJcg53Z7rKz+LUwywiHaAGLzk272561	rogid:KT1zw5OuZthyscvNa/4lW1iJz2Q9606	intact-crc:476679CEDB72B3CC|rigid:yDID0/eyWtb3ezHp4X3gzaUExYY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84251	uniprotkb:P10586	intact:EBI-22302798	intact:EBI-7188069|uniprotkb:Q5T022|uniprotkb:Q5W9G2|intact:MINT-1189049|uniprotkb:D3DPX7|uniprotkb:Q5T021|uniprotkb:D3DPX6|uniprotkb:Q86WS0|ensembl:ENSP00000353030.4	psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name)	psi-mi:ptprf_human(display_long)|uniprotkb:PTPRF(gene name)|psi-mi:PTPRF(display_short)|uniprotkb:LAR(gene name synonym)|uniprotkb:Leukocyte common antigen related(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302805|imex:IM-27647-49	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219754.1|refseq:WP_010725138.1|mint:O84251"	"efo:""Orphanet:180188""|ensembl:ENSG00000142949.17(gene)|ensembl:ENST00000359947.9(transcript)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007185""(cell surface receptor protein tyrosine phosphatase signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008201""(heparin binding)|go:""GO:0016477""(cell migration)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031102""(neuron projection regeneration)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035373""(chondroitin sulfate proteoglycan binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0048679""(regulation of axon regeneration)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0099560""(synaptic membrane adhesion)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1900121""(negative regulation of receptor binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR050713|mint:P10586|rcsb pdb:1LAR|rcsb pdb:2DJU|rcsb pdb:2DN7|rcsb pdb:2EDX|rcsb pdb:2EDY|rcsb pdb:2YD5|rcsb pdb:2YD8|rcsb pdb:4N5U|rcsb pdb:6KR4|rcsb pdb:6TPT|rcsb pdb:6TPU|rcsb pdb:6TPV|rcsb pdb:6TPW|reactome:R-HSA-388844|reactome:R-HSA-77387|reactome:R-HSA-8849932|refseq:NP_002831.2|refseq:NP_569707.2|panther:PTHR19134(orthology-group)"	-	-	comment:mint|comment:homomint	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561	rogid:JLPH3tIxOkyVmJ0mZsBZ+TanLVk9606	intact-crc:7715BD18E8620EB3|rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84251	uniprotkb:P35610	intact:EBI-22302798	intact:EBI-6621955|uniprotkb:A6NC40|uniprotkb:A8K3P4|uniprotkb:A9Z1V7|uniprotkb:B4DU95|uniprotkb:Q5T0X4|uniprotkb:Q8N1E4|ensembl:ENSP00000356591.3	psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name)	"psi-mi:soat1_human(display_long)|uniprotkb:SOAT1(gene name)|psi-mi:SOAT1(display_short)|uniprotkb:ACACT(gene name synonym)|uniprotkb:ACACT1(gene name synonym)|uniprotkb:ACAT(gene name synonym)|uniprotkb:ACAT1(gene name synonym)|uniprotkb:SOAT(gene name synonym)|uniprotkb:STAT(gene name synonym)|uniprotkb:""Acyl-coenzyme A:cholesterol acyltransferase 1""(gene name synonym)|uniprotkb:Cholesterol acyltransferase 1(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302805|imex:IM-27647-49	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219754.1|refseq:WP_010725138.1|mint:O84251"	"refseq:XP_011508213.1|refseq:NP_001239440.1|refseq:NP_001239441.1|refseq:NP_003092.4|ensembl:ENSG00000057252.13(gene)|ensembl:ENST00000367619.8(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0004772""(sterol O-acyltransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0010742""(macrophage derived foam cell differentiation)|go:""GO:0010878""(cholesterol storage)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0034379""(very-low-density lipoprotein particle assembly)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0034736""(cholesterol O-acyltransferase activity)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042986""(positive regulation of amyloid precursor protein biosynthetic process)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|interpro:IPR030687|mint:P35610|rcsb pdb:6L47|rcsb pdb:6L48|rcsb pdb:6P2J|rcsb pdb:6P2P|rcsb pdb:6VUM|reactome:R-HSA-8964038|panther:PTHR10408(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561	rogid:jX8d8x9ZYOdpE2Vg+C5ECuX9zQQ9606	intact-crc:7715BD18E8620EB3|rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84251	uniprotkb:Q8WU67	intact:EBI-22302798	intact:EBI-2876553|ensembl:ENSP00000289119.2|uniprotkb:O43411|uniprotkb:B0YIV0|uniprotkb:B7Z5C2	psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name)	psi-mi:abhd3_human(display_long)|uniprotkb:ABHD3(gene name)|psi-mi:ABHD3(display_short)|uniprotkb:Abhydrolase domain-containing protein 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302805|imex:IM-27647-49	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219754.1|refseq:WP_010725138.1|mint:O84251"	"ensembl:ENSG00000158201.10(gene)|ensembl:ENST00000289119.7(transcript)|go:""GO:0004623""(phospholipase A2 activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006656""(phosphatidylcholine biosynthetic process)|go:""GO:0008126""(acetylesterase activity)|go:""GO:0008970""(phospholipase A1 activity)|go:""GO:0046470""(phosphatidylcholine metabolic process)|go:""GO:0047372""(monoacylglycerol lipase activity)|go:""GO:0047498""(calcium-dependent phospholipase A2 activity)|go:""GO:0047499""(calcium-independent phospholipase A2 activity)|go:""GO:0051792""(medium-chain fatty acid biosynthetic process)|go:""GO:0051793""(medium-chain fatty acid catabolic process)|go:""GO:0052739""(obsolete phosphatidylserine 1-acylhydrolase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR029058|interpro:IPR050960|mint:Q8WU67|reactome:R-HSA-1483191|refseq:NP_001295185.1|refseq:NP_001295186.1|refseq:NP_612213.2|panther:PTHR10794(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561	rogid:QGMm0R1GsOz+kODPipFvZi1/tqg9606	intact-crc:7715BD18E8620EB3|rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84251	uniprotkb:Q9UBE0	intact:EBI-22302798	intact:EBI-743154|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6|ensembl:ENSP00000270225.6|intact:EBI-21351343	psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name)	psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302805|imex:IM-27647-49	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219754.1|refseq:WP_010725138.1|mint:O84251"	"refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N|ensembl:ENSG00000142230.13(gene)|ensembl:ENST00000270225.12(transcript)|go:""GO:0004839""(ubiquitin activating enzyme activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0016925""(protein sumoylation)|go:""GO:0031510""(SUMO activating enzyme complex)|go:""GO:0033235""(positive regulation of protein sumoylation)|go:""GO:0043008""(ATP-dependent protein binding)|go:""GO:0044388""(small protein activating enzyme binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|interpro:IPR045886|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|panther:PTHR10953(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561	rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606	intact-crc:7715BD18E8620EB3|rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84251	uniprotkb:Q9H0P0	intact:EBI-22302798	intact:EBI-3918356|intact:EBI-25600615|uniprotkb:Q7L3G6|uniprotkb:B8ZZC4|uniprotkb:Q6NXS6|uniprotkb:Q9UC45|uniprotkb:A8K253|uniprotkb:Q9UC42|uniprotkb:Q9UC44|uniprotkb:B2RAA5|uniprotkb:Q6IPZ1|uniprotkb:Q9UC43|uniprotkb:Q9P0P5	psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name)	psi-mi:5nt3a_human(display_long)|uniprotkb:NT5C3A(gene name)|psi-mi:NT5C3A(display_short)|uniprotkb:Cytosolic 5'-nucleotidase 3(gene name synonym)|uniprotkb:Cytosolic 5'-nucleotidase III(gene name synonym)|uniprotkb:NT5C3(gene name synonym)|uniprotkb:P5N1(gene name synonym)|uniprotkb:Pyrimidine 5'-nucleotidase 1(gene name synonym)|uniprotkb:UMPH1(gene name synonym)|uniprotkb:Uridine 5'-monophosphate hydrolase 1(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:HSPC233(orf name)|uniprotkb:7-methylguanosine phosphate-specific 5'-nucleotidase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302805|imex:IM-27647-49	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219754.1|refseq:WP_010725138.1|mint:O84251"	"go:""GO:0000166""(nucleotide binding)|go:""GO:0000215""(tRNA 2'-phosphotransferase activity)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006213""(pyrimidine nucleoside metabolic process)|go:""GO:0008253""(5'-nucleotidase activity)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0016604""(nuclear body)|go:""GO:0051607""(defense response to virus)|go:""GO:0106411""(obsolete XMP 5'-nucleosidase activity)|interpro:IPR006434(HAD-superfamily hydrolase, subfamily IE)|interpro:IPR023214|interpro:IPR036412|mint:Q9H0P0|rcsb pdb:2CN1|rcsb pdb:2JGA|rcsb pdb:2VKQ|reactome:R-HSA-73621|refseq:NP_001002009.1|refseq:NP_001002010.1|refseq:NP_001159590.1|refseq:NP_057573.2|refseq:XP_011513711.1|efo:""Orphanet:35120""|panther:PTHR13045(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561	rogid:IMqgR3fhBBTmQWKVhLlMIhK+s4Y9606	intact-crc:7715BD18E8620EB3|rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84251	uniprotkb:Q9NX61	intact:EBI-22302798	intact:EBI-6138599|uniprotkb:Q7L2Y1|uniprotkb:B3KUE0|uniprotkb:G5E9M6|ensembl:ENSP00000162044.7	psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name)	psi-mi:t161a_human(display_long)|uniprotkb:TMEM161A(gene name)|psi-mi:TMEM161A(display_short)|uniprotkb:Adaptive response to oxidative stress protein 29(gene name synonym)|uniprotkb:UNQ582/PRO1152(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302805|imex:IM-27647-49	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219754.1|refseq:WP_010725138.1|mint:O84251"	"refseq:NP_060284.1|refseq:NP_001243695.1|ensembl:ENSG00000064545.15(gene)|ensembl:ENST00000162044.14(transcript)|go:""GO:0016020""(membrane)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034644""(cellular response to UV)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR019395|mint:Q9NX61|panther:PTHR13624(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561	rogid:VVl+h1R9nV0jkQjR4xUzsUe4qKU9606	intact-crc:7715BD18E8620EB3|rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84251	uniprotkb:Q9HAV0	intact:EBI-22302798	intact:EBI-358539|uniprotkb:B3KMH5|uniprotkb:D3DNR8|ensembl:ENSP00000232564.3|ensembl:ENSP00000501882.1|ensembl:ENSP00000502628.1	psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name)	psi-mi:gbb4_human(display_long)|uniprotkb:GNB4(gene name)|psi-mi:GNB4(display_short)|uniprotkb:Transducin beta chain 4(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302805|imex:IM-27647-49	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219754.1|refseq:WP_010725138.1|mint:O84251"	"ensembl:ENSG00000114450.11(gene)|ensembl:ENST00000232564.8(transcript)|ensembl:ENST00000674862.1(transcript)|ensembl:ENST00000676128.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005834""(heterotrimeric G-protein complex)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045202""(synapse)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9HAV0|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9856530|reactome:R-HSA-997272|refseq:NP_067642.1|refseq:XP_005247749.1|refseq:XP_006713784.1|efo:""Orphanet:352670""|panther:PTHR19850(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561	rogid:L6hFuZe1Luk8YTFW+posXDa2Qj49606	intact-crc:7715BD18E8620EB3|rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84251	uniprotkb:P54709	intact:EBI-22302798	intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371.3	psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name)	psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302805|imex:IM-27647-49	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219754.1|refseq:WP_010725138.1|mint:O84251"	"refseq:NP_001670.1|dip:DIP-50717N|ensembl:ENSG00000069849.11(gene)|ensembl:ENST00000286371.8(transcript)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005890""(""sodium:potassium-exchanging ATPase complex"")|go:""GO:0006883""(intracellular sodium ion homeostasis)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030007""(intracellular potassium ion homeostasis)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0035725""(sodium ion transmembrane transport)|go:""GO:0036126""(sperm flagellum)|go:""GO:0036376""(sodium ion export across plasma membrane)|go:""GO:0042470""(melanosome)|go:""GO:0050821""(protein stabilization)|go:""GO:0051117""(ATPase binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071805""(potassium ion transmembrane transport)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0086009""(membrane repolarization)|go:""GO:1901018""(positive regulation of potassium ion transmembrane transporter activity)|go:""GO:1903278""(positive regulation of sodium ion export across plasma membrane)|go:""GO:1903288""(positive regulation of potassium ion import across plasma membrane)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|panther:PTHR11523(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561	rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606	intact-crc:7715BD18E8620EB3|rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84251	uniprotkb:Q9H8H3	intact:EBI-22302798	intact:EBI-1390168|uniprotkb:Q9H7R3|uniprotkb:Q9UHZ7|uniprotkb:Q9Y422|ensembl:ENSP00000331787.4|ensembl:ENSP00000447542.1|ensembl:ENSP00000448785.1	psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name)	psi-mi:tmt1a_human(display_long)|uniprotkb:TMT1A(gene name)|psi-mi:TMT1A(display_short)|uniprotkb:METTL7A(gene name synonym)|uniprotkb:Methyltransferase-like protein 7A(gene name synonym)|uniprotkb:Protein AAM-B(gene name synonym)|uniprotkb:Thiol methyltransferase 1A(gene name synonym)|uniprotkb:PRO0066(orf name)|uniprotkb:UNQ1902/PRO4348(orf name)|uniprotkb:N6-adenosine-methyltransferase TMT1A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302805|imex:IM-27647-49	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219754.1|refseq:WP_010725138.1|mint:O84251"	"refseq:NP_054752.3|refseq:XP_006719395.1|ensembl:ENSG00000185432.12(gene)|ensembl:ENST00000332160.5(transcript)|ensembl:ENST00000547104.1(transcript)|ensembl:ENST00000548553.1(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001734""(""mRNA m(6)A methyltransferase activity"")|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0008173""(RNA methyltransferase activity)|go:""GO:0016020""(membrane)|go:""GO:0018708""(thiol S-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0042476""(odontogenesis)|go:""GO:0180035""(lncRNA processing)|go:""GO:1904724""(tertiary granule lumen)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|interpro:IPR052356|mint:Q9H8H3|reactome:R-HSA-6798695|panther:PTHR42912(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561	rogid:b8PnE+BClVn1MzOlg0uIaqDSOaU9606	intact-crc:7715BD18E8620EB3|rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84251	uniprotkb:Q9Y3E5	intact:EBI-22302798	intact:EBI-1056751|uniprotkb:Q9NTE5|uniprotkb:B3KUY4|ensembl:ENSP00000376758.2|ensembl:ENSP00000464327.1	psi-mi:o84251_chltr(display_long)|uniprotkb:CT_249(locus name)	psi-mi:pth2_human(display_long)|uniprotkb:PTRH2(gene name)|psi-mi:PTRH2(display_short)|uniprotkb:BIT1(gene name synonym)|uniprotkb:PTH2(gene name synonym)|uniprotkb:CGI-147(orf name)|uniprotkb:Bcl-2 inhibitor of transcription 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302805|imex:IM-27647-49	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219754.1|refseq:WP_010725138.1|mint:O84251"	"efo:""Orphanet:456312""|ensembl:ENSG00000141378.15(gene)|ensembl:ENST00000393038.3(transcript)|ensembl:ENST00000470557.2(transcript)|go:""GO:0004045""(peptidyl-tRNA hydrolase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:2000210""(positive regulation of anoikis)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR002833(Peptidyl-tRNA hydrolase, PTH2)|interpro:IPR023476|mint:Q9Y3E5|rcsb pdb:1Q7S|reactome:R-HSA-5689880|refseq:NP_001015509.1|refseq:NP_057161.1|refseq:XP_011523189.1|panther:PTHR12649(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:Qrz9/Xb6BG0jCeKOJb19bBygXxo272561	rogid:E0QOhTNtGBt5CQ3gPebnOhoKvdU9606	intact-crc:7715BD18E8620EB3|rigid:w0x7du7EkeaypeTnQJiNbSV1b7Q	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:Q9Y487	intact:EBI-22302824	intact:EBI-988630|uniprotkb:Q6NUM0|uniprotkb:A8K026|ensembl:ENSP00000332247.2	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	"psi-mi:vpp2_human(display_long)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2(gene name synonym)|uniprotkb:TJ6(gene name synonym)|uniprotkb:ATP6V0A2(gene name)|psi-mi:ATP6V0A2(display_short)|uniprotkb:""Lysosomal H(+)-transporting ATPase V0 subunit a 2""(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"ensembl:ENSG00000185344.15(gene)|ensembl:ENST00000330342.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006955""(immune response)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051117""(ATPase binding)|go:""GO:0061795""(Golgi lumen acidification)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|mint:Q9Y487|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:NP_036595.2|efo:""Orphanet:2834""|efo:""Orphanet:357074""|panther:PTHR11629(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:I4UxvwiAe4ObvfgL15K2lzNKuOA9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:Q93050	intact:EBI-22302824	intact:EBI-2891238|uniprotkb:Q8N5G7|uniprotkb:Q9NSX0|intact:EBI-4324496|uniprotkb:B7Z3B7|ensembl:ENSP00000342951.3|ensembl:ENSP00000515539.1	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	psi-mi:vpp1_human(display_long)|uniprotkb:ATP6V0A1(gene name)|psi-mi:ATP6V0A1(display_short)|uniprotkb:ATP6N1(gene name synonym)|uniprotkb:ATP6N1A(gene name synonym)|uniprotkb:VPP1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"go:""GO:1902600""(proton transmembrane transport)|ensembl:ENSG00000033627.18(gene)|ensembl:ENST00000343619.9(transcript)|ensembl:ENST00000703901.1(transcript)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0042470""(melanosome)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051117""(ATPase binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|mint:Q93050|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:NP_001123492.1|refseq:NP_001123493.1|refseq:NP_005168.2|efo:""Orphanet:528084""|panther:PTHR11629(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:3htDhXCA9potj7i32HoA2j3Sfqw9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:P61421	intact:EBI-22302824	intact:EBI-954063|uniprotkb:P12953|uniprotkb:Q02547|ensembl:ENSP00000290949.3	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	psi-mi:va0d1_human(display_long)|uniprotkb:Vacuolar proton pump subunit d 1(gene name synonym)|uniprotkb:V-ATPase AC39 subunit(gene name synonym)|uniprotkb:V-ATPase 40 kDa accessory protein(gene name synonym)|uniprotkb:32 kDa accessory protein(gene name synonym)|uniprotkb:ATP6V0D1(gene name)|psi-mi:ATP6V0D1(display_short)|uniprotkb:ATP6D(gene name synonym)|uniprotkb:VPATPD(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"refseq:NP_004682.2|dip:DIP-47435N|ensembl:ENSG00000159720.13(gene)|ensembl:ENST00000290949.8(transcript)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007034""(vacuolar transport)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0033181""(plasma membrane proton-transporting V-type ATPase complex)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0043679""(axon terminus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|mint:P61421|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|rcsb pdb:7UNF|reactome:R-HSA-1222556|reactome:R-HSA-381038|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-9857377|panther:PTHR11028(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:3a/yIxEF9LMwAZUR3npGQrw8xNo9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:O75787	intact:EBI-22302824	intact:EBI-2512037|uniprotkb:Q8NG15|uniprotkb:Q8NBP3|uniprotkb:Q5QTQ7|uniprotkb:Q9UG89|uniprotkb:Q96FV6|uniprotkb:Q9H2P8|uniprotkb:Q96LB5|uniprotkb:Q6T7F5|uniprotkb:B7Z9I3|ensembl:ENSP00000490083.1	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	"psi-mi:renr_human(display_long)|uniprotkb:ATP6AP2(gene name)|psi-mi:ATP6AP2(display_short)|uniprotkb:ATP6IP2(gene name synonym)|uniprotkb:CAPER(gene name synonym)|uniprotkb:ELDF10(gene name synonym)|uniprotkb:Renin/prorenin receptor(gene name synonym)|uniprotkb:""ATPase H(+)-transporting lysosomal accessory protein 2""(gene name synonym)|uniprotkb:""ATPase H(+)-transporting lysosomal-interacting protein 2""(gene name synonym)|uniprotkb:Vacuolar ATP synthase membrane sector-associated protein M8-9(gene name synonym)|uniprotkb:N14F(gene name synonym)|uniprotkb:Embryonic liver differentiation factor 10(gene name synonym)|uniprotkb:HT028(orf name)|uniprotkb:MSTP009(orf name)|uniprotkb:PSEC0072(orf name)|uniprotkb:ER-localized type I transmembrane adapter(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"efo:""Orphanet:363654""|efo:""Orphanet:93952""|ensembl:ENSG00000182220.15(gene)|ensembl:ENST00000636580.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0002003""(angiotensin maturation)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0021626""(central nervous system maturation)|go:""GO:0021903""(rostrocaudal neural tube patterning)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030424""(axon)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0032591""(dendritic spine membrane)|go:""GO:0032914""(positive regulation of transforming growth factor beta1 production)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0048069""(eye pigmentation)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0051452""(intracellular pH reduction)|go:""GO:0060323""(head morphogenesis)|go:""GO:0061795""(Golgi lumen acidification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR012493(Renin receptor-like)|mint:O75787|rcsb pdb:3LBS|rcsb pdb:3LC8|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:NP_005756.2|panther:PTHR13351(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:v4lEPX23LdYqPi8dQX4MZG+tQZg9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:Q96G23	intact:EBI-22302824	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688.6|ensembl:ENSP00000357950.5	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418.20(gene)|ensembl:ENST00000271688.10(transcript)|ensembl:ENST00000368954.10(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0030148""(sphingolipid biosynthetic process)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0046513""(ceramide biosynthetic process)|go:""GO:0048681""(negative regulation of axon regeneration)|go:""GO:0050291""(sphingosine N-acyltransferase activity)|go:""GO:1900148""(negative regulation of Schwann cell migration)|go:""GO:1905045""(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|panther:PTHR12560(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:Q06136	intact:EBI-22302824	intact:EBI-3909166|uniprotkb:B2R5Y1|uniprotkb:B4DMX0|ensembl:ENSP00000494352.1	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	psi-mi:kdsr_human(display_long)|uniprotkb:KDSR(gene name)|psi-mi:KDSR(display_short)|uniprotkb:FVT1(gene name synonym)|uniprotkb:3-dehydrosphinganine reductase(gene name synonym)|uniprotkb:Follicular variant translocation protein 1(gene name synonym)|uniprotkb:SDR35C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 35C member 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"ensembl:ENSG00000119537.18(gene)|ensembl:ENST00000645214.2(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006666""(3-keto-sphinganine metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0030148""(sphingolipid biosynthetic process)|go:""GO:0047560""(3-dehydrosphinganine reductase activity)|go:""GO:0070402""(NADPH binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|interpro:IPR045022|mint:Q06136|reactome:R-HSA-1660661|refseq:NP_002026.1|efo:""Orphanet:316""|efo:""Orphanet:317""|panther:PTHR43550(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:Qeo5s672s/qK8CE52sS1Pr01kFY9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:P24539	intact:EBI-22302824	intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737.3	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	"psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:""ATP synthase proton-transporting mitochondrial F(0) complex subunit B1""(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"refseq:NP_001679.2|ensembl:ENSG00000116459.11(gene)|ensembl:ENST00000369722.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0015078""(proton transmembrane transporter activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0016020""(membrane)|go:""GO:0021762""(substantia nigra development)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045263""(""obsolete proton-transporting ATP synthase complex, coupling factor F(o)"")|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|rcsb pdb:8H9F|rcsb pdb:8H9G|rcsb pdb:8H9J|rcsb pdb:8H9K|rcsb pdb:8H9M|rcsb pdb:8H9N|rcsb pdb:8H9Q|rcsb pdb:8H9R|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|panther:PTHR12733(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:n1HuorsLzONcID7ccOL9qEsODLE9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:Q96NT0	intact:EBI-22302824	intact:EBI-2810325|uniprotkb:Q9BR88|ensembl:ENSP00000259229.2|uniprotkb:B4DJ47	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	psi-mi:cc115_human(display_long)|uniprotkb:CCDC115(gene name)|psi-mi:CCDC115(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"ensembl:ENSG00000136710.10(gene)|ensembl:ENST00000259229.7(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0016020""(membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070072""(vacuolar proton-transporting V-type ATPase complex assembly)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR040357|mint:Q96NT0|reactome:R-HSA-8980692|refseq:NP_001308047.1|refseq:NP_001308048.1|refseq:NP_115733.2|efo:""Orphanet:468684""|panther:PTHR31996(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:cUCb36pVMieoV7ZwXQPtD/kIAXY9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:P30049	intact:EBI-22302824	intact:EBI-1049505|uniprotkb:Q6FG90|uniprotkb:D6W5Y3|ensembl:ENSP00000215375.1|ensembl:ENSP00000378995.1|ensembl:ENSP00000464863.1	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	psi-mi:atpd_human(display_long)|uniprotkb:ATP5F1D(gene name)|psi-mi:ATP5F1D(display_short)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:ATP5D(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"ensembl:ENSG00000099624.8(gene)|ensembl:ENST00000215375.7(transcript)|ensembl:ENST00000395633.5(transcript)|ensembl:ENST00000591660.5(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0009060""(aerobic respiration)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0033615""(mitochondrial proton-transporting ATP synthase complex assembly)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045261""(""obsolete proton-transporting ATP synthase complex, catalytic core F(1)"")|go:""GO:0046688""(response to copper ion)|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|interpro:IPR036794|interpro:IPR048937|mint:P30049|rcsb pdb:8H9F|rcsb pdb:8H9J|rcsb pdb:8H9M|rcsb pdb:8H9Q|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|refseq:NP_001001975.1|refseq:NP_001678.1|efo:""Orphanet:254913""|panther:PTHR13822(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:OA8if7wpjwV6hkkaLqPyz6YDljc9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:O75947	intact:EBI-22302824	intact:EBI-724024|uniprotkb:Q9H3J4|uniprotkb:B2R5L6|ensembl:ENSP00000301587.4	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863.12(gene)|ensembl:ENST00000301587.9(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0015078""(proton transmembrane transporter activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045263""(""obsolete proton-transporting ATP synthase complex, coupling factor F(o)"")|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|rcsb pdb:8H9F|rcsb pdb:8H9G|rcsb pdb:8H9J|rcsb pdb:8H9K|rcsb pdb:8H9M|rcsb pdb:8H9N|rcsb pdb:8H9Q|rcsb pdb:8H9R|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|reactome:R-HSA-9837999|panther:PTHR12700(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:P56134	intact:EBI-22302824	intact:EBI-712794|uniprotkb:O76079|uniprotkb:Q96L83|uniprotkb:Q9BTI8|uniprotkb:C9J8H9|uniprotkb:F8W7V3|uniprotkb:Q6IBB3|ensembl:ENSP00000292475.4|intact:EBI-11047094	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	psi-mi:atpk_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase membrane subunit f(gene name synonym)|uniprotkb:ATP5J2(gene name synonym)|uniprotkb:ATP5JL(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"refseq:NP_001003713.1|refseq:NP_004880.1|refseq:NP_001003714.1|refseq:NP_001034267.1|ensembl:ENSG00000241468.8(gene)|ensembl:ENST00000292475.8(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045263""(""obsolete proton-transporting ATP synthase complex, coupling factor F(o)"")|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR019344|mint:P56134|rcsb pdb:8H9F|rcsb pdb:8H9J|rcsb pdb:8H9M|rcsb pdb:8H9Q|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|panther:PTHR13080(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:+WS7rjFef6JE+mlZ4Q8TF2A+G0E9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:P56385	intact:EBI-22302824	intact:EBI-2270000|uniprotkb:Q0D2L9|ensembl:ENSP00000306003.4	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	psi-mi:atp5i_human(display_long)|uniprotkb:ATP5ME(gene name)|psi-mi:ATP5ME(display_short)|uniprotkb:ATP5I(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)|uniprotkb:ATP5K(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"refseq:NP_009031.1|ensembl:ENSG00000169020.10(gene)|ensembl:ENST00000304312.5(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0015078""(proton transmembrane transporter activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045263""(""obsolete proton-transporting ATP synthase complex, coupling factor F(o)"")|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:P56385|rcsb pdb:8H9F|rcsb pdb:8H9J|rcsb pdb:8H9M|rcsb pdb:8H9Q|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|panther:PTHR12427(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:NYpqzWQYASXwSwU/BYDTMU2tJjI9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84362	uniprotkb:P03928	intact:EBI-22302824	intact:EBI-3439833|intact:EBI-3450125|uniprotkb:Q34771|ensembl:ENSP00000355265.1	psi-mi:o84362_chltr(display_long)|uniprotkb:CT_357(locus name)	psi-mi:atp8_human(display_long)|uniprotkb:MT-ATP8(gene name)|psi-mi:MT-ATP8(display_short)|uniprotkb:ATP8(gene name synonym)|uniprotkb:ATPASE8(gene name synonym)|uniprotkb:MTATP8(gene name synonym)|uniprotkb:A6L(gene name synonym)|uniprotkb:F-ATPase subunit 8(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302831|imex:IM-27647-25	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219866.1|refseq:WP_010725169.1|mint:O84362"	"efo:""Orphanet:254913""|efo:""Orphanet:397750""|efo:""Orphanet:480""|ensembl:ENSG00000228253.1(gene)|ensembl:ENST00000361851.1(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0015078""(proton transmembrane transporter activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045263""(""obsolete proton-transporting ATP synthase complex, coupling factor F(o)"")|interpro:IPR001421(ATPase, F0 complex, subunit 8, mitochondrial, Metazoan)|interpro:IPR039017|mint:P03928|rcsb pdb:8H9F|rcsb pdb:8H9J|rcsb pdb:8H9M|rcsb pdb:8H9Q|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|refseq:YP_003024030.1|panther:PTHR13722(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/10	rogid:+OisYy7E1fl/rfP1oL1Srsfabfs272561	rogid:8LbAeHQBEFnML9W9QP2R2igsr0U9606	intact-crc:AFBAAE0F1E8F6365|rigid:R1VMKrKuLaB4lzNklsVqSCrHmsA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:O43149	intact:EBI-22302849	intact:EBI-715672|uniprotkb:Q6NXG0|uniprotkb:Q6ZRA1|uniprotkb:Q6ZSF4|uniprotkb:Q9NVB9|uniprotkb:A7MBM5|ensembl:ENSP00000371051.2	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:zzef1_human(display_long)|uniprotkb:ZZEF1(gene name)|psi-mi:ZZEF1(display_short)|uniprotkb:KIAA0399(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_055928.3|ensembl:ENSG00000074755.15(gene)|ensembl:ENST00000381638.7(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0035064""(methylated histone binding)|go:""GO:0070577""(lysine-acetylated histone binding)|go:""GO:0140566""(histone reader activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011992(EF-Hand type)|interpro:IPR040099|interpro:IPR041986|interpro:IPR043145|interpro:IPR047052|mint:O43149|panther:PTHR22772(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:LpYXMInET7VBZ/ZLV23wuQksKTA9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q9BZ29	intact:EBI-22302849	intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761.1	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387.22(gene)|ensembl:ENST00000652315.1(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045296""(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|interpro:IPR046769|interpro:IPR046770|interpro:IPR046773|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231|panther:PTHR23317(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q9C0C9	intact:EBI-22302849	intact:EBI-2339946|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q9H6E6|ensembl:ENSP00000323687.6	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_071349.3|ensembl:ENSG00000175931.13(gene)|ensembl:ENST00000319380.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|rcsb pdb:7UN3|rcsb pdb:7UN6|reactome:R-HSA-983168|panther:PTHR46116(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:P14735	intact:EBI-22302849	intact:EBI-2556886|uniprotkb:Q5T5N2|uniprotkb:D3DR35|uniprotkb:B2R721|uniprotkb:B7ZAU2|ensembl:ENSP00000265986.6	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:ide_human(display_long)|uniprotkb:IDE(gene name)|psi-mi:IDE(display_short)|uniprotkb:Insulin protease(gene name synonym)|uniprotkb:Insulysin(gene name synonym)|uniprotkb:Abeta-degrading protease(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_004960.2|refseq:NP_001159418.1|dip:DIP-55771N|ensembl:ENSG00000119912.18(gene)|ensembl:ENST00000265986.11(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010815""(bradykinin catabolic process)|go:""GO:0010992""(ubiquitin recycling)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0030163""(protein catabolic process)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0042277""(peptide binding)|go:""GO:0042447""(hormone catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0043559""(insulin binding)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0050435""(amyloid-beta metabolic process)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0150094""(amyloid-beta clearance by cellular catabolic process)|go:""GO:1901142""(insulin metabolic process)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1903715""(regulation of aerobic respiration)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR032632|interpro:IPR050626|interpro:IPR054734|mint:P14735|rcsb pdb:2G47|rcsb pdb:2G48|rcsb pdb:2G49|rcsb pdb:2G54|rcsb pdb:2G56|rcsb pdb:2JBU|rcsb pdb:2JG4|rcsb pdb:2WBY|rcsb pdb:2WC0|rcsb pdb:2WK3|rcsb pdb:2YPU|rcsb pdb:3CWW|rcsb pdb:3E4A|rcsb pdb:3E4Z|rcsb pdb:3E50|rcsb pdb:3H44|rcsb pdb:3HGZ|rcsb pdb:3N56|rcsb pdb:3N57|rcsb pdb:3OFI|rcsb pdb:3QZ2|rcsb pdb:4DTT|rcsb pdb:4DWK|rcsb pdb:4GS8|rcsb pdb:4GSC|rcsb pdb:4GSF|rcsb pdb:4IFH|rcsb pdb:4IOF|rcsb pdb:4LTE|rcsb pdb:4M1C|rcsb pdb:4NXO|rcsb pdb:4PES|rcsb pdb:4PF7|rcsb pdb:4PF9|rcsb pdb:4PFC|rcsb pdb:4QIA|rcsb pdb:4RAL|rcsb pdb:4RE9|rcsb pdb:5CJO|rcsb pdb:5UOE|rcsb pdb:5WOB|rcsb pdb:6B3Q|rcsb pdb:6B70|rcsb pdb:6B7Y|rcsb pdb:6B7Z|rcsb pdb:6BF6|rcsb pdb:6BF7|rcsb pdb:6BF8|rcsb pdb:6BF9|rcsb pdb:6BFC|rcsb pdb:6BYZ|rcsb pdb:6EDS|rcsb pdb:6MQ3|rcsb pdb:7K1D|rcsb pdb:7K1E|rcsb pdb:7K1F|rcsb pdb:7RZE|rcsb pdb:7RZF|rcsb pdb:7RZG|rcsb pdb:7RZH|rcsb pdb:7RZI|reactome:R-HSA-5689880|reactome:R-HSA-77387|reactome:R-HSA-9033241|panther:PTHR43690(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:dwngN3kUOExC5qapSgF01YhBNAM9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q5T447	intact:EBI-22302849	intact:EBI-2691157|uniprotkb:B3KPV7|uniprotkb:B3KRH4|uniprotkb:Q5T448|uniprotkb:Q9H783|ensembl:ENSP00000361245.4	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:hecd3_human(display_long)|uniprotkb:HECT domain-containing protein 3(gene name synonym)|uniprotkb:HECTD3(gene name)|psi-mi:HECTD3(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase HECTD3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_078878.3|ensembl:ENSG00000126107.15(gene)|ensembl:ENST00000372172.5(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019905""(syntaxin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR000569(HECT)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR035983|interpro:IPR042469|mint:Q5T447|reactome:R-HSA-983168|panther:PTHR46654(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:laodrF8CReKmM4d6n3sHGBmQB6Q9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q66LE6	intact:EBI-22302849	intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970.2	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_060931.2|refseq:NP_001278239.1|ensembl:ENSG00000175470.20(gene)|ensembl:ENST00000455566.6(transcript)|go:""GO:0000159""(protein phosphatase type 2A complex)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0005829""(cytosol)|go:""GO:0010458""(exit from mitosis)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0051301""(cell division)|go:""GO:0051983""(regulation of chromosome segregation)|go:""GO:0140767""(enzyme-substrate adaptor activity)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|panther:PTHR11871(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:P51398	intact:EBI-22302849	intact:EBI-355912|uniprotkb:Q13044|uniprotkb:Q96Q20|uniprotkb:Q68CT7|uniprotkb:B4DP59|uniprotkb:E7EM60|uniprotkb:B4DY62|ensembl:ENSP00000341692.3|ensembl:ENSP00000357320.5	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:rt29_human(display_long)|uniprotkb:DAP3(gene name)|psi-mi:DAP3(display_short)|uniprotkb:MRPS29(gene name synonym)|uniprotkb:Death-associated protein 3(gene name synonym)|uniprotkb:Ionizing radiation resistance conferring protein(gene name synonym)|uniprotkb:28S ribosomal protein S29, mitochondrial(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_001186778.1|refseq:NP_004623.1|refseq:NP_387506.1|refseq:NP_001186779.1|refseq:NP_001186780.1|refseq:XP_005245537.1|refseq:XP_005245538.1|ensembl:ENSG00000132676.16(gene)|ensembl:ENST00000343043.7(transcript)|ensembl:ENST00000368336.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005763""(mitochondrial small ribosomal subunit)|go:""GO:0032543""(mitochondrial translation)|go:""GO:0097190""(apoptotic signaling pathway)|interpro:IPR008092(Death associated protein 3)|interpro:IPR019368|interpro:IPR027417|mint:P51398|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|rcsb pdb:7P2E|rcsb pdb:7PNX|rcsb pdb:7PNY|rcsb pdb:7PNZ|rcsb pdb:7PO0|rcsb pdb:7PO1|rcsb pdb:7PO2|rcsb pdb:7PO3|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8CSP|rcsb pdb:8CSQ|rcsb pdb:8CSR|rcsb pdb:8CSS|rcsb pdb:8CST|rcsb pdb:8CSU|rcsb pdb:8K2A|rcsb pdb:8OIR|rcsb pdb:8OIS|rcsb pdb:8QRK|rcsb pdb:8QRL|rcsb pdb:8QRM|rcsb pdb:8QRN|rcsb pdb:8XT0|rcsb pdb:8XT2|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_016857780.1|refseq:XP_016857781.1|refseq:XP_016857782.1|panther:PTHR12810(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:xSIyqKH4F49Iu+AVuVThJWsi9EA9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:P82650	intact:EBI-22302849	intact:EBI-1050752|ensembl:ENSP00000418008.1|ensembl:ENSP00000505414.1|ensembl:ENSP00000510396.1|uniprotkb:Q9H3I1	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:rt22_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:C3orf5(gene name synonym)|uniprotkb:RPMS22(gene name synonym)|uniprotkb:GK002(orf name)|uniprotkb:28S ribosomal protein S22, mitochondrial(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"ensembl:ENSG00000175110.14(gene)|ensembl:ENST00000495075.5(transcript)|ensembl:ENST00000680020.1(transcript)|ensembl:ENST00000688697.1(transcript)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|mint:P82650|go:""GO:0005743""(mitochondrial inner membrane)|rcsb pdb:3J9M|go:""GO:0005761""(mitochondrial ribosome)|go:""GO:0005763""(mitochondrial small ribosomal subunit)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR019374|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|rcsb pdb:7P2E|rcsb pdb:7PNX|rcsb pdb:7PNY|rcsb pdb:7PNZ|rcsb pdb:7PO0|rcsb pdb:7PO1|rcsb pdb:7PO2|rcsb pdb:7PO3|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8CSP|rcsb pdb:8CSQ|rcsb pdb:8CSR|rcsb pdb:8CSS|rcsb pdb:8CST|rcsb pdb:8CSU|rcsb pdb:8K2A|rcsb pdb:8OIR|rcsb pdb:8OIS|rcsb pdb:8QRK|rcsb pdb:8QRL|rcsb pdb:8QRM|rcsb pdb:8QRN|rcsb pdb:8XT0|rcsb pdb:8XT2|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_064576.1|efo:""Orphanet:137908""|efo:""Orphanet:243""|panther:PTHR13071(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:T0htF4/rvOZUZ3RcuCjWvEg9iTE9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q8N4Q1	intact:EBI-22302849	intact:EBI-2562213|uniprotkb:A8K3Z9|uniprotkb:Q96AI2|uniprotkb:Q96MY6|intact:EBI-25633037|ensembl:ENSP00000380122.3	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:mia40_human(display_long)|uniprotkb:MIA40(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 4(gene name synonym)|uniprotkb:CHCHD4(gene name)|psi-mi:CHCHD4(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_001091972.1|refseq:NP_653237.1|ensembl:ENSG00000163528.13(gene)|ensembl:ENST00000396914.4(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0018171""(peptidyl-cysteine oxidation)|go:""GO:0022417""(obsolete protein maturation by protein folding)|go:""GO:0033108""(mitochondrial respiratory chain complex assembly)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0043504""(mitochondrial DNA repair)|go:""GO:0045041""(protein import into mitochondrial intermembrane space)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051084""('de novo' post-translational protein folding)|go:""GO:0160203""(mitochondrial disulfide relay system)|go:""GO:1901857""(positive regulation of cellular respiration)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR010625(CHCH)|interpro:IPR039289|mint:Q8N4Q1|rcsb pdb:2K3J|rcsb pdb:2L0Y|reactome:R-HSA-1268020|dip:DIP-48483N|panther:PTHR21622(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:ACH8CTQRjTwq7nz6toGTrn3VHlE9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q9Y4Y9	intact:EBI-22302849	intact:EBI-373007|ensembl:ENSP00000410758.2	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:lsm5_human(display_long)|uniprotkb:LSM5(gene name)|psi-mi:LSM5(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"panther:PTHR20971(orthology-group)|ensembl:ENSG00000106355.10(gene)|ensembl:ENST00000450169.7(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005688""(U6 snRNP)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0009617""(response to bacterium)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0120115""(Lsm2-8 complex)|go:""GO:1990726""(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR033871|interpro:IPR047575|mint:Q9Y4Y9|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8QO9|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RM5|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_001124182.1|refseq:NP_001132971.1|refseq:NP_036454.1|dip:DIP-31162N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:EeF2r4qY+BFrZTyTCT+i4ccskf49606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q9Y4B6	intact:EBI-22302849	intact:EBI-1996353|uniprotkb:Q2YD74|uniprotkb:Q8TBD9|uniprotkb:Q9HCA1|uniprotkb:Q9UG37|ensembl:ENSP00000393183.2|ensembl:ENSP00000506880.1|intact:EBI-2559078|intact:EBI-28988191	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:dcaf1_human(display_long)|uniprotkb:DCAF1(gene name)|psi-mi:DCAF1(display_short)|uniprotkb:HIV-1 Vpr-binding protein(gene name synonym)|uniprotkb:KIAA0800(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:VPRBP(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"go:""GO:1990244""(histone H2AT120 kinase activity)|refseq:NP_001165375.1|refseq:NP_055518.1|refseq:XP_011532575.1|refseq:XP_011532576.1|refseq:XP_011532577.1|refseq:XP_011532578.1|refseq:XP_011532579.1|ensembl:ENSG00000145041.17(gene)|ensembl:ENST00000423656.5(transcript)|ensembl:ENST00000684031.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0033151""(""V(D)J recombination"")|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035212""(cell competition in a multicellular organism)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|rcsb pdb:4P7I|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|mint:Q9Y4B6|rcsb pdb:3WA0|rcsb pdb:4CC9|rcsb pdb:4PXW|rcsb pdb:4Z8L|rcsb pdb:5AJA|rcsb pdb:5JK7|rcsb pdb:6N45|rcsb pdb:6ZUE|rcsb pdb:6ZX9|rcsb pdb:7OKQ|rcsb pdb:7SSE|rcsb pdb:7UFV|rcsb pdb:7V7B|rcsb pdb:7V7C|rcsb pdb:8F8E|rcsb pdb:8OG5|rcsb pdb:8OG6|rcsb pdb:8OG7|rcsb pdb:8OG8|rcsb pdb:8OG9|rcsb pdb:8OGA|rcsb pdb:8OGB|rcsb pdb:8OGC|rcsb pdb:8OO5|rcsb pdb:8OOD|rcsb pdb:9BHR|rcsb pdb:9BHS|rcsb pdb:9C1Q|reactome:R-HSA-983168|refseq:XP_005276810.1|refseq:XP_005276812.1|panther:PTHR13129(orthology-group)|refseq:XP_016863035.1|refseq:XP_016863036.1|refseq:XP_016863037.1|refseq:XP_016863038.1|refseq:XP_016863039.1|dip:DIP-47048N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:qs3qG0MM135EE/DjC1S/gCLRFhc9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:O00410	intact:EBI-22302849	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219.3|ensembl:ENSP00000418393.1|ensembl:ENSP00000499125.1|intact:EBI-21353074	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_002262.3|refseq:XP_005254109.1|refseq:XP_005254110.1|ensembl:ENSG00000065150.21(gene)|ensembl:ENST00000357602.7(transcript)|ensembl:ENST00000490680.5(transcript)|ensembl:ENST00000651721.2(transcript)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003723""(RNA binding)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0006610""(ribosomal protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0045736""(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0071230""(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|refseq:XP_016876051.1|dip:DIP-41042N|panther:PTHR10527(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q8TEX9	intact:EBI-22302849	intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453.6|ensembl:ENSP00000494795.1	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_078934.3|panther:PTHR10527(orthology-group)|ensembl:ENSG00000196497.17(gene)|ensembl:ENSG00000285248.2(gene)|ensembl:ENST00000354464.11(transcript)|ensembl:ENST00000644546.2(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0061608""(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK|rcsb pdb:7UNK|rcsb pdb:8DYO|dip:DIP-32944N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q5H9R7	intact:EBI-22302849	intact:EBI-355498|uniprotkb:Q3B7I1|uniprotkb:Q7L4R8|uniprotkb:Q8N3B2|uniprotkb:Q96MB2|uniprotkb:Q9H2K5|uniprotkb:Q9H2K6|uniprotkb:Q9HCL4|uniprotkb:Q9NUY3|uniprotkb:Q3I4Y0|uniprotkb:Q3KR35|uniprotkb:Q68CR3|intact:EBI-25598259|ensembl:ENSP00000377389.2|intact:EBI-28971860	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:pp6r3_human(display_long)|uniprotkb:PPP6R3(gene name)|psi-mi:PPP6R3(display_short)|uniprotkb:C11orf23(gene name synonym)|uniprotkb:KIAA1558(gene name synonym)|uniprotkb:PP6R3(gene name synonym)|uniprotkb:SAPL(gene name synonym)|uniprotkb:Sporulation-induced transcript 4-associated protein SAPL(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym)|uniprotkb:SAPS3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_001157632.1|refseq:NP_001157633.1|refseq:NP_001157634.1|refseq:NP_001157635.1|refseq:NP_001157636.1|refseq:NP_060782.2|refseq:XP_011543442.1|ensembl:ENSG00000110075.15(gene)|ensembl:ENST00000393800.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0019903""(protein phosphatase binding)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q5H9R7|reactome:R-HSA-171319|reactome:R-HSA-204005|refseq:XP_006718676.1|refseq:XP_006718677.1|refseq:XP_006718681.1|refseq:XP_006718687.1|refseq:XP_016873451.1|refseq:XP_016873452.1|refseq:XP_016873455.1|panther:PTHR12634(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:9hU14AmzYI9nORfchfMtLoyRecA9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q14566	intact:EBI-22302849	intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156.2	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"ensembl:ENSG00000076003.5(gene)|ensembl:ENST00000264156.3(transcript)|go:""GO:0000727""(double-strand break repair via break-induced replication)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030174""(regulation of DNA-templated DNA replication initiation)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042555""(MCM complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071162""(CMG complex)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1902969""(mitotic DNA replication)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:7W1Y|rcsb pdb:7W68|rcsb pdb:8B9D|rcsb pdb:8S09|rcsb pdb:8S0A|rcsb pdb:8S0B|rcsb pdb:8S0D|rcsb pdb:8S0E|rcsb pdb:8S0F|rcsb pdb:8W0E|rcsb pdb:8W0F|rcsb pdb:8W0G|rcsb pdb:8W0I|rcsb pdb:9CAQ|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_005906.2|dip:DIP-31727N|panther:PTHR11630(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q96EY7	intact:EBI-22302849	intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630.7	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Pentatricopeptide repeat domain-containing protein 3, mitochondrial(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_060422.4|ensembl:ENSG00000132300.19(gene)|ensembl:ENST00000254630.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005763""(mitochondrial small ribosomal subunit)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006417""(regulation of translation)|go:""GO:0019843""(rRNA binding)|go:""GO:0032543""(mitochondrial translation)|go:""GO:0043024""(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|rcsb pdb:6ZSB|interpro:IPR055063|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|rcsb pdb:7P2E|rcsb pdb:7PNX|rcsb pdb:7PNY|rcsb pdb:7PNZ|rcsb pdb:7PO0|rcsb pdb:7PO1|rcsb pdb:7PO2|rcsb pdb:7PO3|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8CSP|rcsb pdb:8CSQ|rcsb pdb:8CSR|rcsb pdb:8CSS|rcsb pdb:8CST|rcsb pdb:8CSU|rcsb pdb:8K2A|rcsb pdb:8OIR|rcsb pdb:8OIS|rcsb pdb:8QRK|rcsb pdb:8QRL|rcsb pdb:8QRM|rcsb pdb:8QRN|rcsb pdb:8XT0|rcsb pdb:8XT2|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR16276(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:O15355	intact:EBI-22302849	intact:EBI-725702|ensembl:ENSP00000342778.4	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_817092.1|dip:DIP-29404N|ensembl:ENSG00000115241.11(gene)|ensembl:ENST00000344034.5(transcript)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0035970""(peptidyl-threonine dephosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|panther:PTHR13832(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q9Y5Q8	intact:EBI-22302849	intact:EBI-1045409|uniprotkb:Q8N2U7|uniprotkb:Q8N857|uniprotkb:Q96GD9|uniprotkb:Q9H4P2|uniprotkb:A6NI44|uniprotkb:A6NJB9|uniprotkb:Q5T7U2|uniprotkb:Q5T7U3|intact:EBI-2556713|ensembl:ENSP00000361169.5	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:tf3c5_human(display_long)|uniprotkb:Transcription factor IIIC subunit epsilon(gene name synonym)|uniprotkb:TF3C-epsilon(gene name synonym)|uniprotkb:Transcription factor IIIC 63 kDa subunit(gene name synonym)|uniprotkb:GTF3C5(gene name)|psi-mi:GTF3C5(display_short)|uniprotkb:CDABP0017(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_001116295.1|refseq:NP_036219.2|refseq:NP_001273638.1|dip:DIP-50823N|ensembl:ENSG00000148308.18(gene)|ensembl:ENST00000372097.10(transcript)|go:""GO:0000127""(transcription factor TFIIIC complex)|go:""GO:0000995""(RNA polymerase III general transcription initiation factor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006383""(transcription by RNA polymerase III)|go:""GO:0006384""(transcription initiation at RNA polymerase III promoter)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0042791""(5S class rRNA transcription by RNA polymerase III)|go:""GO:0042797""(tRNA transcription by RNA polymerase III)|interpro:IPR019136|interpro:IPR040454|interpro:IPR041499|interpro:IPR042536|mint:Q9Y5Q8|rcsb pdb:8CLK|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|panther:PTHR13230(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:Cb1wPs3qn4+Up/g7WgOMDEFtp+M9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q969S3	intact:EBI-22302849	intact:EBI-2687480|ensembl:ENSP00000310042.2	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:zn622_human(display_long)|uniprotkb:ZPR9(gene name synonym)|uniprotkb:Zinc finger-like protein 9(gene name synonym)|uniprotkb:ZNF622(gene name)|psi-mi:ZNF622(display_short)|uniprotkb:Zinc finger protein 622(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_219482.1|ensembl:ENSG00000173545.5(gene)|ensembl:ENST00000308683.3(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008631""(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:""GO:0030687""(preribosome, large subunit precursor)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:1990275""(preribosome binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661|mint:Q969S3|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:9GMO|panther:PTHR13182(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:WUzJA1E/Gz78ud7PgHYxKxUSvU49606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q96GA3	intact:EBI-22302849	intact:EBI-2558389|uniprotkb:Q96JX8|ensembl:ENSP00000356548.5	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:ltv1_human(display_long)|uniprotkb:LTV1(gene name)|psi-mi:LTV1(display_short)|uniprotkb:C6orf93(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_116249.2|ensembl:ENSG00000135521.9(gene)|ensembl:ENST00000367576.6(transcript)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0030688""(preribosome, small subunit precursor)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|interpro:IPR007307(Low temperature viability protein)|mint:Q96GA3|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:7WTT|rcsb pdb:7WTU|rcsb pdb:7WTW|rcsb pdb:7WTX|rcsb pdb:7WTZ|rcsb pdb:7WU0|reactome:R-HSA-6791226|panther:PTHR21531(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:Csfx8GS5hoclLY1BYki/uUKoSIM9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:P13489	intact:EBI-22302849	intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402.2|ensembl:ENSP00000348515.5|ensembl:ENSP00000380729.3|ensembl:ENSP00000380738.1|ensembl:ENSP00000380739.2|ensembl:ENSP00000416589.2|ensembl:ENSP00000433999.1|ensembl:ENSP00000435594.1|ensembl:ENSP00000478664.1|ensembl:ENSP00000479004.1|ensembl:ENSP00000479966.1|ensembl:ENSP00000480036.1|ensembl:ENSP00000484572.1|ensembl:ENSP00000487753.1|ensembl:ENSP00000487940.1|ensembl:ENSP00000488734.1	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|ensembl:ENSG00000023191.17(gene)|ensembl:ENSG00000276230.4(gene)|ensembl:ENST00000354420.7(transcript)|ensembl:ENST00000356187.9(transcript)|ensembl:ENST00000397604.7(transcript)|ensembl:ENST00000397614.5(transcript)|ensembl:ENST00000397615.6(transcript)|ensembl:ENST00000438658.6(transcript)|ensembl:ENST00000533410.5(transcript)|ensembl:ENST00000534797.5(transcript)|ensembl:ENST00000612988.4(transcript)|ensembl:ENST00000617351.4(transcript)|ensembl:ENST00000618184.3(transcript)|ensembl:ENST00000619599.4(transcript)|ensembl:ENST00000621211.2(transcript)|ensembl:ENST00000632527.1(transcript)|ensembl:ENST00000632954.1(transcript)|ensembl:ENST00000633287.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008428""(ribonuclease inhibitor activity)|go:""GO:0016477""(cell migration)|go:""GO:0030027""(lamellipodium)|go:""GO:0032311""(angiogenin-PRI complex)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0036416""(tRNA stabilization)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|interpro:IPR050637|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|refseq:XP_016873595.1|panther:PTHR24112(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:P63151	intact:EBI-22302849	intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113.3	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914.11(gene)|ensembl:ENST00000380737.8(transcript)|go:""GO:0000159""(protein phosphatase type 2A complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0043278""(response to morphine)|go:""GO:0051983""(regulation of chromosome segregation)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140767""(enzyme-substrate adaptor activity)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|rcsb pdb:8SO0|rcsb pdb:8TTB|rcsb pdb:8TWE|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|reactome:R-HSA-9860927|dip:DIP-29398N|panther:PTHR11871(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:evS6klM2alZXtMthVsshKkrNgiA9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:P82675	intact:EBI-22302849	intact:EBI-1054287|uniprotkb:Q96LJ6|uniprotkb:Q9BWI4|uniprotkb:Q9BYC4|uniprotkb:Q4ZFY5|ensembl:ENSP00000272418.2	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:rt05_human(display_long)|uniprotkb:MRPS5(gene name)|psi-mi:MRPS5(display_short)|uniprotkb:28S ribosomal protein S5, mitochondrial(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_114108.1|ensembl:ENSG00000144029.14(gene)|ensembl:ENST00000272418.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005763""(mitochondrial small ribosomal subunit)|go:""GO:0006412""(translation)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|interpro:IPR048584|mint:P82675|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|rcsb pdb:7P2E|rcsb pdb:7PNX|rcsb pdb:7PNY|rcsb pdb:7PNZ|rcsb pdb:7PO0|rcsb pdb:7PO1|rcsb pdb:7PO2|rcsb pdb:7PO3|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8CSP|rcsb pdb:8CSQ|rcsb pdb:8CSR|rcsb pdb:8CSS|rcsb pdb:8CST|rcsb pdb:8CSU|rcsb pdb:8K2A|rcsb pdb:8OIR|rcsb pdb:8OIS|rcsb pdb:8QRK|rcsb pdb:8QRL|rcsb pdb:8QRM|rcsb pdb:8QRN|rcsb pdb:8XT0|rcsb pdb:8XT2|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR13718(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:l+aZgmDVWWimuUiH4IS4FG1cwlQ9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q9BT78	intact:EBI-22302849	intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|uniprotkb:B3KST5|ensembl:ENSP00000264389.2	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_057213.2|refseq:NP_001244935.1|refseq:NP_001317656.1|dip:DIP-34516N|ensembl:ENSG00000138663.9(gene)|ensembl:ENST00000264389.7(transcript)|go:""GO:0000338""(protein deneddylation)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0016607""(nuclear speck)|go:""GO:0019784""(deNEDDylase activity)|go:""GO:0030054""(cell junction)|go:""GO:0045116""(protein neddylation)|go:""GO:2000434""(regulation of protein neddylation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR041406|interpro:IPR054559|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:8H38|rcsb pdb:8H3A|rcsb pdb:8H3F|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|panther:PTHR10855(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q9NTK5	intact:EBI-22302849	intact:EBI-766468|uniprotkb:Q5BJD7|uniprotkb:Q8NCI8|uniprotkb:Q96CU1|uniprotkb:Q96SV2|uniprotkb:Q9P1D3|uniprotkb:Q9UNY9|uniprotkb:Q9Y6G4|ensembl:ENSP00000284719.3|uniprotkb:D7EHM2	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:ola1_human(display_long)|uniprotkb:GTPBP9(gene name synonym)|uniprotkb:GTP-binding protein 9(gene name synonym)|uniprotkb:OLA1(gene name)|psi-mi:OLA1(display_short)|uniprotkb:PTD004(orf name)|uniprotkb:PRO2455(orf name)|uniprotkb:DNA damage-regulated overexpressed in cancer 45(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_001011708.1|refseq:NP_037473.3|dip:DIP-34591N|ensembl:ENSG00000138430.16(gene)|ensembl:ENST00000284719.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR004095(TGS)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR023192|interpro:IPR027417|interpro:IPR031167|interpro:IPR041706|mint:Q9NTK5|rcsb pdb:2OHF|reactome:R-HSA-114608|panther:PTHR23305(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:aQk5XBcKpx1YSW4mHtyRsTpimvk9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q9BQA1	intact:EBI-22302849	intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090.5	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym)|uniprotkb:Methylosome protein 50(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_077007.1|refseq:NP_001303993.1|refseq:NP_001303991.1|refseq:NP_001303992.1|ensembl:ENSG00000116455.14(gene)|ensembl:ENST00000235090.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007309""(oocyte axis specification)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008327""(methyl-CpG binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0031465""(Cul4B-RING E3 ubiquitin ligase complex)|go:""GO:0034709""(methylosome)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0060528""(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:""GO:0060767""(epithelial cell proliferation involved in prostate gland development)|go:""GO:0060770""(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR052139|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7BO7|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|rcsb pdb:7MX7|rcsb pdb:7MXA|rcsb pdb:7MXC|rcsb pdb:8VEX|rcsb pdb:7MXG|rcsb pdb:7MXN|rcsb pdb:7S0U|rcsb pdb:7S1P|rcsb pdb:7S1Q|rcsb pdb:7S1R|rcsb pdb:7S1S|rcsb pdb:7SER|rcsb pdb:7SES|rcsb pdb:7U30|rcsb pdb:7UOH|rcsb pdb:7UY1|rcsb pdb:7UYF|rcsb pdb:7ZUP|rcsb pdb:7ZUQ|rcsb pdb:7ZUU|rcsb pdb:7ZUY|rcsb pdb:7ZV2|rcsb pdb:7ZVL|rcsb pdb:7ZVU|rcsb pdb:8CSG|rcsb pdb:8CTB|rcsb pdb:8CYI|rcsb pdb:8G1U|rcsb pdb:8VEO|rcsb pdb:8VET|rcsb pdb:8VEU|rcsb pdb:8VEW|rcsb pdb:8VEY|rcsb pdb:9C10|rcsb pdb:9EYU|rcsb pdb:9EYV|rcsb pdb:9EYW|rcsb pdb:9EYX|reactome:R-HSA-191859|reactome:R-HSA-3214858|dip:DIP-38172N|panther:PTHR46853(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:0q4wunYtHalObC8r1wphhelIpr49606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q9Y676	intact:EBI-22302849	intact:EBI-750085|uniprotkb:Q9BS27|uniprotkb:A6NDQ0|uniprotkb:Q659G4|intact:EBI-1050511|ensembl:ENSP00000259873.4|ensembl:ENSP00000383438.3|ensembl:ENSP00000397790.2|ensembl:ENSP00000398494.2|ensembl:ENSP00000402718.2|ensembl:ENSP00000414972.2|ensembl:ENSP00000415703.2	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:rt18b_human(display_long)|uniprotkb:28S ribosomal protein S18-2, mitochondrial(gene name synonym)|uniprotkb:C6orf14(gene name synonym)|uniprotkb:MRPS18B(gene name)|psi-mi:MRPS18B(display_short)|uniprotkb:28S ribosomal protein S18b, mitochondrial(gene name synonym)|uniprotkb:Small ribosomal subunit protein bS18b(gene name synonym)|uniprotkb:HSPC183(orf name)|uniprotkb:PTD017(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_054765.1|ensembl:ENSG00000203624.10(gene)|ensembl:ENSG00000204568.12(gene)|ensembl:ENSG00000223775.8(gene)|ensembl:ENSG00000226111.8(gene)|ensembl:ENSG00000227420.8(gene)|ensembl:ENSG00000229861.8(gene)|ensembl:ENSG00000233813.8(gene)|ensembl:ENST00000259873.5(transcript)|ensembl:ENST00000327800.10(transcript)|ensembl:ENST00000412451.6(transcript)|ensembl:ENST00000426945.6(transcript)|ensembl:ENST00000430402.6(transcript)|ensembl:ENST00000451032.6(transcript)|ensembl:ENST00000454427.6(transcript)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005763""(mitochondrial small ribosomal subunit)|go:""GO:0006412""(translation)|go:""GO:0030054""(cell junction)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR001648(Ribosomal protein S18)|interpro:IPR036870|interpro:IPR040054|mint:Q9Y676|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|rcsb pdb:7P2E|rcsb pdb:7PNX|rcsb pdb:7PNY|rcsb pdb:7PNZ|rcsb pdb:7PO0|rcsb pdb:7PO1|rcsb pdb:7PO2|rcsb pdb:7PO3|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8CSP|rcsb pdb:8CSQ|rcsb pdb:8CSR|rcsb pdb:8CSS|rcsb pdb:8CST|rcsb pdb:8CSU|rcsb pdb:8K2A|rcsb pdb:8OIR|rcsb pdb:8OIS|rcsb pdb:8QRK|rcsb pdb:8QRL|rcsb pdb:8QRM|rcsb pdb:8QRN|rcsb pdb:8XT0|rcsb pdb:8XT2|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|dip:DIP-29894N|panther:PTHR13329(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:DFGekxKm74bAo8IWpOi8LDITWqc9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:P54105	intact:EBI-22302849	intact:EBI-724693|uniprotkb:Q0VDK6|uniprotkb:Q9NRD2|uniprotkb:Q9NRD3|uniprotkb:B2RCS9|ensembl:ENSP00000433919.1|ensembl:ENSP00000434311.1	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:icln_human(display_long)|uniprotkb:Chloride conductance regulatory protein ICln(gene name synonym)|uniprotkb:Chloride channel, nucleotide sensitive 1A(gene name synonym)|uniprotkb:Chloride ion current inducer protein(gene name synonym)|uniprotkb:Reticulocyte pICln(gene name synonym)|uniprotkb:CLNS1A(gene name)|psi-mi:CLNS1A(display_short)|uniprotkb:ICLN(gene name synonym)|uniprotkb:CLCI(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_001284.1|refseq:NP_001298128.1|refseq:NP_001298129.1|refseq:NP_001298130.1|refseq:NP_001298131.1|ensembl:ENSG00000074201.9(gene)|ensembl:ENST00000525428.6(transcript)|ensembl:ENST00000528364.1(transcript)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006821""(chloride transport)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0034709""(methylosome)|go:""GO:0034715""(pICln-Sm protein complex)|go:""GO:0045292""(mRNA cis splicing, via spliceosome)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR003521(Nucleotide-sensitive chloride conductance regulator)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039924|mint:P54105|rcsb pdb:6V0O|reactome:R-HSA-191859|dip:DIP-44185N|panther:PTHR21399(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:dGx9UwPj9VBp1CiPTRCXnT3IYt89606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:P82930	intact:EBI-22302849	intact:EBI-1048516|uniprotkb:Q9BVI7|ensembl:ENSP00000380531.3	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:rt34_human(display_long)|uniprotkb:MRPS34(gene name)|psi-mi:MRPS34(display_short)|uniprotkb:28S ribosomal protein S34, mitochondrial(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_076425.1|ensembl:ENSG00000074071.15(gene)|ensembl:ENST00000397375.7(transcript)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005763""(mitochondrial small ribosomal subunit)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR032053|mint:P82930|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|rcsb pdb:7P2E|rcsb pdb:7PNX|rcsb pdb:7PNY|rcsb pdb:7PNZ|rcsb pdb:7PO0|rcsb pdb:7PO1|rcsb pdb:7PO2|rcsb pdb:7PO3|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8CSP|rcsb pdb:8CSQ|rcsb pdb:8CSR|rcsb pdb:8CSS|rcsb pdb:8CST|rcsb pdb:8CSU|rcsb pdb:8K2A|rcsb pdb:8OIR|rcsb pdb:8OIS|rcsb pdb:8QRK|rcsb pdb:8QRL|rcsb pdb:8QRM|rcsb pdb:8QRN|rcsb pdb:8XT0|rcsb pdb:8XT2|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001287829.1|panther:PTHR28589(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:UTZkYPSJqThFKwoB7D5sH6g0zuc9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q9Y2R5	intact:EBI-22302849	intact:EBI-1046443|uniprotkb:Q86X15|ensembl:ENSP00000285298.4	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:rt17_human(display_long)|uniprotkb:MRPS17(gene name)|psi-mi:MRPS17(display_short)|uniprotkb:RPMS17(gene name synonym)|uniprotkb:HSPC011(orf name)|uniprotkb:28S ribosomal protein S17, mitochondrial(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_057053.1|ensembl:ENSG00000239789.6(gene)|ensembl:ENST00000285298.9(transcript)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005763""(mitochondrial small ribosomal subunit)|go:""GO:0006412""(translation)|go:""GO:0019843""(rRNA binding)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR039193|mint:Q9Y2R5|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|rcsb pdb:7P2E|rcsb pdb:7PNX|rcsb pdb:7PNY|rcsb pdb:7PNZ|rcsb pdb:7PO0|rcsb pdb:7PO1|rcsb pdb:7PO2|rcsb pdb:7PO3|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8CSP|rcsb pdb:8CSQ|rcsb pdb:8CSR|rcsb pdb:8CSS|rcsb pdb:8CST|rcsb pdb:8CSU|rcsb pdb:8K2A|rcsb pdb:8OIR|rcsb pdb:8OIS|rcsb pdb:8QRK|rcsb pdb:8QRL|rcsb pdb:8QRM|rcsb pdb:8QRN|rcsb pdb:8XT0|rcsb pdb:8XT2|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR24088(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:UDEpLcg5pGMMYvvc72HnPf9169U9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:O75147	intact:EBI-22302849	intact:EBI-1223896|uniprotkb:A4KVA5|uniprotkb:Q96IW3|intact:EBI-7903201|intact:MINT-8415345|uniprotkb:A4KVA4|uniprotkb:S4R3M6|ensembl:ENSP00000385636.1|intact:EBI-28983679|uniprotkb:A0A024R468	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:obsl1_human(display_long)|uniprotkb:OBSL1(gene name)|psi-mi:OBSL1(display_short)|uniprotkb:KIAA0657(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"efo:""Orphanet:2616""|ensembl:ENSG00000124006.15(gene)|ensembl:ENST00000404537.6(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0014704""(intercalated disc)|go:""GO:0030018""(Z disc)|go:""GO:0031430""(M band)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050775""(positive regulation of dendrite morphogenesis)|go:""GO:0055003""(cardiac myofibril assembly)|go:""GO:1990393""(3M complex)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR052385|mint:O75147|rcsb pdb:2CPC|rcsb pdb:2E6P|rcsb pdb:2E6Q|rcsb pdb:2LU7|rcsb pdb:2LVC|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:3KNB|rcsb pdb:5FM5|reactome:R-HSA-8951664|refseq:NP_001166879.1|refseq:NP_001166902.1|refseq:NP_056126.1|dip:DIP-38340N|panther:PTHR35971(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:HFxqB+AxsXH/zWXgCj/ODfSmqQQ9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q6IA86	intact:EBI-22302849	intact:EBI-2680411|uniprotkb:Q53GZ0|uniprotkb:Q8N5C2|uniprotkb:Q9H9N0|uniprotkb:Q96GV4|uniprotkb:Q687Y8|uniprotkb:Q9NV81|uniprotkb:Q96PI7|uniprotkb:B4DTG0|uniprotkb:A8KAI6|uniprotkb:B4DXP0|uniprotkb:E7EP23|uniprotkb:E9PCX0|intact:EBI-28972003|ensembl:ENSP00000350967.6	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:elp2_human(display_long)|uniprotkb:STATIP1(gene name synonym)|uniprotkb:SHINC-2(gene name synonym)|uniprotkb:STAT3-interacting protein 1(gene name synonym)|uniprotkb:ELP2(gene name)|psi-mi:ELP2(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_001229804.1|refseq:NP_001229805.1|refseq:NP_001229806.1|refseq:NP_001229807.1|refseq:NP_001229808.1|refseq:NP_060725.1|ensembl:ENSG00000134759.14(gene)|ensembl:ENST00000358232.11(transcript)|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0006417""(regulation of translation)|go:""GO:0008023""(transcription elongation factor complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0033588""(elongator holoenzyme complex)|go:""GO:0046425""(regulation of receptor signaling pathway via JAK-STAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037289|mint:Q6IA86|rcsb pdb:8PTX|rcsb pdb:8PTY|rcsb pdb:8PTZ|rcsb pdb:8PU0|reactome:R-HSA-3214847|dip:DIP-56235N|panther:PTHR44111(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:CkQQYyJ00MHOYXKhvVnwgAhdP2M9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:Q96EB6	intact:EBI-22302849	intact:EBI-1802965|uniprotkb:Q2XNF6|uniprotkb:Q5JVQ0|uniprotkb:Q9GZR9|uniprotkb:Q9Y6F0|ensembl:ENSP00000212015.6	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:sir1_human(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:SIRT1(gene name)|psi-mi:SIRT1(display_short)|uniprotkb:SIR2L1(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_001135970.1|refseq:NP_036370.2|ensembl:ENSG00000096717.12(gene)|ensembl:ENST00000212015.11(transcript)|go:""GO:0000012""(single strand break repair)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000183""(rDNA heterochromatin formation)|go:""GO:0000720""(pyrimidine dimer repair by nucleotide-excision repair)|go:""GO:0000731""(DNA synthesis involved in DNA repair)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000792""(heterochromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001542""(ovulation from ovarian follicle)|go:""GO:0001650""(fibrillar center)|go:""GO:0001678""(intracellular glucose homeostasis)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0002039""(p53 binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0004407""(histone deacetylase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005677""(chromatin silencing complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006346""(DNA methylation-dependent constitutive heterochromatin formation)|go:""GO:0006476""(protein deacetylation)|go:""GO:0006642""(triglyceride mobilization)|go:""GO:0006974""(DNA damage response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0007517""(muscle organ development)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010868""(negative regulation of triglyceride biosynthetic process)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0010883""(regulation of lipid storage)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016605""(PML body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0017136""(histone deacetylase activity, NAD-dependent)|go:""GO:0018394""(peptidyl-lysine acetylation)|go:""GO:0019213""(deacetylase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031393""(negative regulation of prostaglandin biosynthetic process)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031648""(protein destabilization)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0032041""(histone H3K14 deacetylase activity, NAD-dependent)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032868""(response to insulin)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0033210""(leptin-mediated signaling pathway)|go:""GO:0033553""(rDNA heterochromatin)|go:""GO:0033558""(protein lysine deacetylase activity)|go:""GO:0034391""(regulation of smooth muscle cell apoptotic process)|go:""GO:0034979""(NAD-dependent protein lysine deacetylase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035356""(intracellular triglyceride homeostasis)|go:""GO:0035358""(regulation of peroxisome proliferator activated receptor signaling pathway)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042326""(negative regulation of phosphorylation)|go:""GO:0042393""(histone binding)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042595""(behavioral response to starvation)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043398""(HLH domain binding)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0044321""(response to leptin)|go:""GO:0045348""(positive regulation of MHC class II biosynthetic process)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045722""(positive regulation of gluconeogenesis)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046015""(regulation of transcription by glucose)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0046872""(metal ion binding)|go:""GO:0046969""(histone H3K9 deacetylase activity, NAD-dependent)|go:""GO:0046970""(histone H4K16 deacetylase activity, NAD-dependent)|go:""GO:0050872""(white fat cell differentiation)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0051658""(maintenance of nucleus location)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055089""(fatty acid homeostasis)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0061773""(eNoSc complex)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070403""(NAD+ binding)|go:""GO:0070857""(regulation of bile acid biosynthetic process)|go:""GO:0070914""(UV-damage excision repair)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0090335""(regulation of brown fat cell differentiation)|go:""GO:0090400""(stress-induced premature senescence)|go:""GO:0097009""(energy homeostasis)|go:""GO:0097372""(histone H3K18 deacetylase activity, NAD-dependent)|go:""GO:0106230""(protein depropionylation)|go:""GO:0106231""(NAD-dependent protein-lysine depropionylase activity)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140765""(histone H3K56 deacetylase activity, NAD-dependent)|go:""GO:0140861""(DNA repair-dependent chromatin remodeling)|go:""GO:0140937""(histone H4K12 deacetylase activity, hydrolytic mechanism)|go:""GO:0141050""(histone H3K deacetylase activity)|go:""GO:0141208""(NAD-dependent protein lysine delactylase activity)|go:""GO:0141222""(histone H3K4 deacetylase activity, NAD-dependent)|go:""GO:0160012""(NAD-dependent histone decrotonylase activity)|go:""GO:0170012""(histone H3K18 decrotonylase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901797""(negative regulation of signal transduction by p53 class mediator)|go:""GO:1901984""(negative regulation of protein acetylation)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902424""(negative regulation of attachment of mitotic spindle microtubules to kinetochore)|go:""GO:1904179""(positive regulation of adipose tissue development)|go:""GO:1990254""(keratin filament binding)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000111""(positive regulation of macrophage apoptotic process)|go:""GO:2000481""(positive regulation of cAMP-dependent protein kinase activity)|go:""GO:2000655""(negative regulation of cellular response to testosterone stimulus)|go:""GO:2000757""(negative regulation of peptidyl-lysine acetylation)|go:""GO:2000773""(negative regulation of cellular senescence)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|interpro:IPR050134|mint:Q96EB6|rcsb pdb:4I5I|rcsb pdb:4IF6|rcsb pdb:4IG9|rcsb pdb:4KXQ|rcsb pdb:4ZZH|rcsb pdb:4ZZI|rcsb pdb:4ZZJ|rcsb pdb:5BTR|rcsb pdb:8ANB|reactome:R-HSA-3371453|reactome:R-HSA-400253|reactome:R-HSA-427359|reactome:R-HSA-9617629|reactome:R-HSA-9707616|reactome:R-HSA-9841922|reactome:R-HSA-9854907|reactome:R-HSA-9856649|panther:PTHR11085(orthology-group)|refseq:NP_001300978.1|dip:DIP-29757N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:h3zVepuhRhzlINCluVuAn71Btjc9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:O43251	intact:EBI-22302849	intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0016070""(RNA metabolic process)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0140297""(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR047131|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|panther:PTHR15597(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:eIocECpScMWGhrZslIle29WUyKs9606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84388	uniprotkb:P49354	intact:EBI-22302849	intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423.3	psi-mi:o84388_chltr(display_long)|uniprotkb:CT_383(locus name)	psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302856|imex:IM-27647-27	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219893.1|refseq:WP_009871735.1|mint:O84388"	"refseq:NP_002018.1|ensembl:ENSG00000168522.13(gene)|ensembl:ENST00000302279.8(transcript)|go:""GO:0004660""(protein farnesyltransferase activity)|go:""GO:0004661""(protein geranylgeranyltransferase activity)|go:""GO:0004662""(CAAX-protein geranylgeranyltransferase activity)|go:""GO:0004663""(Rab geranylgeranyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0005953""(CAAX-protein geranylgeranyltransferase complex)|go:""GO:0005965""(protein farnesyltransferase complex)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007323""(peptide pheromone maturation)|go:""GO:0008017""(microtubule binding)|go:""GO:0018343""(protein farnesylation)|go:""GO:0018344""(protein geranylgeranylation)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0071340""(skeletal muscle acetylcholine-gated channel clustering)|go:""GO:0090044""(positive regulation of tubulin deacetylation)|go:""GO:0090045""(positive regulation of deacetylase activity)|go:""GO:1904395""(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002|reactome:R-HSA-9679191|panther:PTHR11129(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/24	rogid:TVSz81pv/SSvsAU5jp6OobILOc0272561	rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606	intact-crc:A90FEB7C2C61F090|rigid:eCvY3s7v7YY5wWYJTLDGfPpSy3s	false	binding-associated region:156-243|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q9Y2H6	intact:EBI-22302898	intact:EBI-2810266|uniprotkb:Q6EVH4|uniprotkb:Q6N020|uniprotkb:B4DYG1|uniprotkb:Q5JVF8|uniprotkb:Q5HYC9|uniprotkb:Q6ZME4|uniprotkb:Q6P9D5|uniprotkb:Q6EVH3|uniprotkb:Q5JVF9|uniprotkb:Q9H1W1|ensembl:ENSP00000417257.1|ensembl:ENSP00000441831.1	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:fnd3a_human(display_long)|uniprotkb:FNDC3A(gene name)|psi-mi:FNDC3A(display_short)|uniprotkb:FNDC3(gene name synonym)|uniprotkb:HUGO(gene name synonym)|uniprotkb:KIAA0970(gene name synonym)|uniprotkb:Human gene expressed in odontoblasts(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"refseq:NP_001073141.1|refseq:NP_055738.3|refseq:XP_011533299.1|refseq:NP_001265367.1|ensembl:ENSG00000102531.16(gene)|ensembl:ENST00000492622.6(transcript)|ensembl:ENST00000541916.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007286""(spermatid development)|go:""GO:0009566""(fertilization)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060009""(Sertoli cell development)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR050617|mint:Q9Y2H6|rcsb pdb:1WK0|rcsb pdb:1X3D|rcsb pdb:1X4X|rcsb pdb:1X5X|rcsb pdb:2CRM|rcsb pdb:2CRZ|refseq:XP_016875929.1|refseq:XP_016875930.1|refseq:XP_016875931.1|panther:PTHR24099(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:7gFZgxAfa590PH85SnEF3oeSNSI9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q58WW2	intact:EBI-22302898	intact:EBI-2559044|ensembl:ENSP00000311949.6|uniprotkb:Q8TB19|uniprotkb:Q8IXH3|uniprotkb:A2A295|uniprotkb:Q7L8I0|uniprotkb:B4DNB8	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:dcaf6_human(display_long)|uniprotkb:DCAF6(gene name)|psi-mi:DCAF6(display_short)|uniprotkb:IQWD1(gene name synonym)|uniprotkb:Nuclear receptor interaction protein(gene name synonym)|uniprotkb:IQ motif and WD repeat-containing protein 1(gene name synonym)|uniprotkb:Androgen receptor complex-associated protein(gene name synonym)|uniprotkb:MSTP055(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"ensembl:ENSG00000143164.16(gene)|ensembl:ENST00000312263.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR045151|mint:Q58WW2|rcsb pdb:3I7O|reactome:R-HSA-8951664|refseq:NP_001017977.1|refseq:NP_001185885.1|refseq:NP_001185886.1|refseq:NP_060912.2|dip:DIP-44678N|panther:PTHR15574(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:1CtoPWPj6fdryvDlC46pXiUguDc9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:O94826	intact:EBI-22302898	intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320.5	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"refseq:NP_055635.3|ensembl:ENSG00000154174.8(gene)|ensembl:ENST00000284320.6(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0002230""(positive regulation of defense response to virus by host)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005742""(mitochondrial outer membrane translocase complex)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0030150""(protein import into mitochondrial matrix)|go:""GO:0030943""(mitochondrion targeting sequence binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045039""(protein insertion into mitochondrial inner membrane)|go:""GO:0045040""(protein insertion into mitochondrial outer membrane)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061052""(negative regulation of cell growth involved in cardiac muscle cell development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097068""(response to thyroxine)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140596""(TOM complex)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|reactome:R-HSA-1268020|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-9692916|reactome:R-HSA-9705671|panther:PTHR46208(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q9UJX3	intact:EBI-22302898	intact:EBI-1384164|uniprotkb:Q96AC4|uniprotkb:Q96GF4|uniprotkb:Q9BU24|uniprotkb:Q9NT16|ensembl:ENSP00000394394.4	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:apc7_human(display_long)|uniprotkb:ANAPC7(gene name)|psi-mi:ANAPC7(display_short)|uniprotkb:APC7(gene name synonym)|uniprotkb:Cyclosome subunit 7(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019903""(protein phosphatase binding)|dip:DIP-39765N|ensembl:ENSG00000196510.14(gene)|ensembl:ENST00000455511.9(transcript)|go:""GO:0000792""(heterochromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005680""(anaphase-promoting complex)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0007420""(brain development)|go:""GO:0031145""(anaphase-promoting complex-dependent catabolic process)|go:""GO:0045842""(positive regulation of mitotic metaphase/anaphase transition)|go:""GO:0051301""(cell division)|go:""GO:0051445""(regulation of meiotic cell cycle)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0140767""(enzyme-substrate adaptor activity)|go:""GO:0141198""(protein branched polyubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX3|rcsb pdb:3FFL|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|rcsb pdb:8PKP|rcsb pdb:8TAR|rcsb pdb:8TAU|rcsb pdb:9GAW|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|panther:PTHR12558(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:lByk++a5wKNCI86NxSWdaY6CBAc9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q01581	intact:EBI-22302898	intact:EBI-1055448|ensembl:ENSP00000322706.6|ensembl:ENSP00000399402.2|uniprotkb:B2RDL8	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:hmcs1_human(display_long)|uniprotkb:3-hydroxy-3-methylglutaryl coenzyme A synthase(gene name synonym)|uniprotkb:HMGCS1(gene name)|psi-mi:HMGCS1(display_short)|uniprotkb:HMGCS(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"ensembl:ENSG00000112972.16(gene)|ensembl:ENST00000325110.11(transcript)|ensembl:ENST00000433297.2(transcript)|go:""GO:0004421""(hydroxymethylglutaryl-CoA synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006084""(acetyl-CoA metabolic process)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0010142""(farnesyl diphosphate biosynthetic process, mevalonate pathway)|go:""GO:0042803""(protein homodimerization activity)|interpro:IPR000590(Hydroxymethylglutaryl-coenzyme A synthase, active site)|interpro:IPR010122(Hydroxymethylglutaryl-CoA synthase, eukaryotic)|interpro:IPR013528(Hydroxymethylglutaryl-coenzyme A synthase, N-terminal)|interpro:IPR013746(Hydroxymethylglutaryl-coenzyme A synthase C-terminal)|interpro:IPR016039(Thiolase-like)|mint:Q01581|rcsb pdb:2P8U|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|refseq:NP_001311148.1|refseq:NP_001311149.1|refseq:NP_001311151.1|refseq:NP_001311152.1|refseq:NP_001311153.1|refseq:NP_001091742.1|refseq:NP_002121.4|refseq:NP_001317592.1|panther:PTHR43323(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:7txkOHhV1hUghX+s35oVhKsmS2c9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q8NBN7	intact:EBI-22302898	intact:EBI-3922765|uniprotkb:Q96G88|uniprotkb:Q6UX79|ensembl:ENSP00000391121.2|ensembl:ENSP00000477512.1	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:rdh13_human(display_long)|uniprotkb:RDH13(gene name)|psi-mi:RDH13(display_short)|uniprotkb:SDR7C3(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 7C member 3(gene name synonym)|uniprotkb:PSEC0082(orf name)|uniprotkb:UNQ736/PRO1430(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"refseq:XP_011524709.1|refseq:NP_612421.1|refseq:XP_005258530.1|ensembl:ENSG00000160439.16(gene)|ensembl:ENSG00000276684.4(gene)|ensembl:ENST00000415061.8(transcript)|ensembl:ENST00000615256.4(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0009644""(response to high light intensity)|go:""GO:0010842""(retina layer formation)|go:""GO:0042462""(eye photoreceptor cell development)|go:""GO:0042574""(retinal metabolic process)|go:""GO:0052650""(""all-trans-retinol dehydrogenase (NADP+) activity"")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q8NBN7|reactome:R-HSA-5365859|refseq:NP_001139443.1|panther:PTHR43157(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:UHfrKddjwiPXJ6xohB99Ua0jGZo9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:O43759	intact:EBI-22302898	intact:EBI-6269521|uniprotkb:A6NP69|uniprotkb:A8K0E2|uniprotkb:O43757|uniprotkb:O43758|uniprotkb:Q53Y02|uniprotkb:Q96J56|uniprotkb:Q9UGZ4|ensembl:ENSP00000332287.5	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:sng1_human(display_long)|uniprotkb:SYNGR1(gene name)|psi-mi:SYNGR1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"refseq:NP_004702.2|refseq:NP_663783.1|refseq:NP_663791.1|ensembl:ENSG00000100321.15(gene)|ensembl:ENST00000328933.10(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0016020""(membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042470""(melanosome)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0048169""(regulation of long-term neuronal synaptic plasticity)|go:""GO:0048172""(regulation of short-term neuronal synaptic plasticity)|go:""GO:0048499""(synaptic vesicle membrane organization)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR008253(Marvel)|interpro:IPR016579(Synaptogyrin)|mint:O43759|rcsb pdb:8A6M|reactome:R-HSA-6798695|panther:PTHR10838(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:1wEiG09j29FhN8v7ZGSOvuK2Ong9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:P62491	intact:EBI-22302898	intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|uniprotkb:B2R4B6|uniprotkb:B4DT13|ensembl:ENSP00000261890.2	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"efo:""Orphanet:178469""|dip:DIP-29138N|ensembl:ENSG00000103769.10(gene)|ensembl:ENST00000261890.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000922""(spindle pole)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005771""(multivesicular body)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0006887""(exocytosis)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0008017""(microtubule binding)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0010971""(positive regulation of G2/M transition of mitotic cell cycle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0031175""(neuron projection development)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031489""(myosin V binding)|go:""GO:0031982""(vesicle)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032402""(melanosome transport)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048227""(plasma membrane to endosome transport)|go:""GO:0051650""(establishment of vesicle localization)|go:""GO:0051959""(dynein light intermediate chain binding)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0061502""(early endosome to recycling endosome transport)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0072594""(establishment of protein localization to organelle)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090150""(establishment of protein localization to membrane)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0098837""(postsynaptic recycling endosome)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:1902017""(regulation of cilium assembly)|go:""GO:1902954""(regulation of early endosome to recycling endosome transport)|go:""GO:1903438""(positive regulation of mitotic cytokinetic process)|go:""GO:1904779""(regulation of protein localization to centrosome)|go:""GO:1990182""(exosomal secretion)|go:""GO:2001135""(regulation of endocytic recycling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050209|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|rcsb pdb:8VOF|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|refseq:NP_001193765.1|refseq:NP_004654.1|panther:PTHR47979(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q8N0U8	intact:EBI-22302898	intact:EBI-11337915|uniprotkb:E7ETM5|uniprotkb:Q6AHW9|uniprotkb:B4E222|uniprotkb:Q6TEK6|ensembl:ENSP00000353998.2|ensembl:ENSP00000497394.1	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:vkorl_human(display_long)|uniprotkb:VKORC1L1(gene name)|psi-mi:VKORC1L1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"refseq:NP_001271271.1|refseq:NP_775788.2|ensembl:ENSG00000196715.7(gene)|ensembl:ENST00000360768.5(transcript)|ensembl:ENST00000648179.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0017187""(peptidyl-glutamic acid carboxylation)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0042373""(vitamin K metabolic process)|go:""GO:0047057""(""vitamin-K-epoxide reductase (warfarin-sensitive) activity"")|go:""GO:0048038""(quinone binding)|interpro:IPR012932(Vitamin K epoxide reductase)|interpro:IPR038354|interpro:IPR042406|mint:Q8N0U8|reactome:R-HSA-6806664|panther:PTHR14519(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:0gdoyZTMoqEjTsPOfeUNSlH4M7k9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q9NVH1	intact:EBI-22302898	intact:EBI-1055336|uniprotkb:Q4VWF5|uniprotkb:Q5VZN0|uniprotkb:Q6PK20|uniprotkb:Q6PK70|uniprotkb:Q8NDM2|uniprotkb:Q96CL7|ensembl:ENSP00000366800.5	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:djc11_human(display_long)|uniprotkb:DNAJC11(gene name)|psi-mi:DNAJC11(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"refseq:NP_060668.2|ensembl:ENSG00000007923.17(gene)|ensembl:ENST00000377577.10(transcript)|go:""GO:0001401""(SAM complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0007007""(inner mitochondrial membrane organization)|go:""GO:0016607""(nuclear speck)|go:""GO:0042407""(cristae formation)|go:""GO:0140275""(MIB complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR024586|interpro:IPR036869|interpro:IPR052243|interpro:IPR055225|mint:Q9NVH1|reactome:R-HSA-8949613|panther:PTHR44157(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:+I9CW/QUSn5NIkn2CRTFzq50c/I9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q9H3G5	intact:EBI-22302898	intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|intact:EBI-1058665|uniprotkb:A4D1A4|ensembl:ENSP00000265394.5|ensembl:ENSP00000379572.3|ensembl:ENSP00000387164.1	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"refseq:NP_061902.2|refseq:NP_112601.3|ensembl:ENSG00000106066.15(gene)|ensembl:ENST00000265394.10(transcript)|ensembl:ENST00000396276.7(transcript)|ensembl:ENST00000409850.5(transcript)|go:""GO:0004185""(serine-type carboxypeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1|panther:PTHR11802(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:antgab61u6D+KmbopQeowXqSqWQ9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q9P0L0	intact:EBI-22302898	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880.3	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"refseq:NP_003565.4|refseq:NP_919415.2|ensembl:ENSG00000101558.14(gene)|ensembl:ENST00000400000.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031982""(vesicle)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035627""(ceramide transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0061025""(membrane fusion)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0090114""(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|dip:DIP-41135N|panther:PTHR10809(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:P84077	intact:EBI-22302898	intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102.5|ensembl:ENSP00000514653.1|ensembl:ENSP00000514654.1|ensembl:ENSP00000514657.1	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"panther:PTHR11711(orthology-group)|efo:""Orphanet:98892""|ensembl:ENSG00000143761.17(gene)|ensembl:ENST00000272102.10(transcript)|ensembl:ENST00000470558.5(transcript)|ensembl:ENST00000478336.5(transcript)|ensembl:ENST00000478424.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0002090""(regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030017""(sarcomere)|go:""GO:0031252""(cell leading edge)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0043005""(neuron projection)|go:""GO:0060292""(long-term synaptic depression)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097061""(dendritic spine organization)|go:""GO:0098586""(cellular response to virus)|go:""GO:1990386""(mitotic cleavage furrow ingression)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR024156|interpro:IPR027417|interpro:IPR045872|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7DN8|rcsb pdb:7DN9|rcsb pdb:7MGE|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9U|rcsb pdb:8D9W|rcsb pdb:8SDW|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505|reactome:R-HSA-9845576|refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:zray9asm6VonxpuJpv0dRBspPt89606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:P38435	intact:EBI-22302898	intact:EBI-10963113|uniprotkb:B4DMC5|uniprotkb:E9PEE1|uniprotkb:Q6GU45|uniprotkb:Q14415|ensembl:ENSP00000233838.3	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:vkgc_human(display_long)|uniprotkb:GGCX(gene name)|psi-mi:GGCX(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:Gamma-glutamyl carboxylase(gene name synonym)|uniprotkb:Peptidyl-glutamate 4-carboxylase(gene name synonym)|uniprotkb:Vitamin K gamma glutamyl carboxylase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"efo:""Orphanet:436274""|efo:""Orphanet:91135""|efo:""Orphanet:98434""|ensembl:ENSG00000115486.13(gene)|ensembl:ENST00000233838.9(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007596""(blood coagulation)|go:""GO:0008488""(gamma-glutamyl carboxylase activity)|go:""GO:0016020""(membrane)|go:""GO:0019842""(vitamin binding)|go:""GO:0036211""(protein modification process)|go:""GO:0042373""(vitamin K metabolic process)|interpro:IPR007782(Vitamin K-dependent gamma-carboxylase)|interpro:IPR011020(HTTM)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR053934|interpro:IPR053935|mint:P38435|reactome:R-HSA-159740|reactome:R-HSA-9673240|refseq:NP_000812.2|refseq:NP_001135741.1|panther:PTHR12639(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:icDLv1KyH9HC3h9enCp9S/nXPmM9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:P49915	intact:EBI-22302898	intact:EBI-1050289|uniprotkb:A8K639|uniprotkb:B4DXV7|uniprotkb:F8W720|ensembl:ENSP00000419851.1	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:guaa_human(display_long)|uniprotkb:GMP synthetase(gene name synonym)|uniprotkb:Glutamine amidotransferase(gene name synonym)|uniprotkb:GMPS(gene name)|psi-mi:GMPS(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"refseq:NP_003866.1|ensembl:ENSG00000163655.16(gene)|ensembl:ENST00000496455.7(transcript)|go:""GO:0003921""(GMP synthase activity)|go:""GO:0003922""(""GMP synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006177""(GMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0009168""(purine ribonucleoside monophosphate biosynthetic process)|interpro:IPR001674(GMP synthase, C-terminal)|interpro:IPR004739(GMP synthase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017926|interpro:IPR022310|interpro:IPR025777|interpro:IPR029062|mint:P49915|rcsb pdb:2VPI|rcsb pdb:2VXO|reactome:R-HSA-73817|reactome:R-HSA-9748787|panther:PTHR11922(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:LYs65bPoqjVG/ZxA6v+yJo3HsLI9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q96D46	intact:EBI-22302898	intact:EBI-2371176|uniprotkb:Q9Y2Z6|uniprotkb:D3DNM7|ensembl:ENSP00000307525.2|ensembl:ENSP00000419004.1	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:nmd3_human(display_long)|uniprotkb:NMD3(gene name)|psi-mi:NMD3(display_short)|uniprotkb:CGI-07(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"ensembl:ENSG00000169251.13(gene)|ensembl:ENST00000351193.7(transcript)|ensembl:ENST00000460469.1(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:1902680""(positive regulation of RNA biosynthetic process)|go:""GO:1904751""(positive regulation of protein localization to nucleolus)|interpro:IPR007064(NMD3)|interpro:IPR039768|interpro:IPR048898|interpro:IPR048899|mint:Q96D46|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|refseq:NP_057022.2|refseq:XP_005247568.1|refseq:XP_005247569.1|dip:DIP-53427N|panther:PTHR12746(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:ufeZYizNnQTOnJjgF+zmyLQphJE9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:Q9BVC4	intact:EBI-22302898	intact:EBI-1387471|intact:EBI-1567843|uniprotkb:Q5M800|uniprotkb:Q86Y18|uniprotkb:Q8WUI5|uniprotkb:Q9HA66|uniprotkb:Q9UJV6|uniprotkb:B4DY00|uniprotkb:B3KMM4|uniprotkb:D3DU88|ensembl:ENSP00000380313.1|ensembl:ENSP00000455046.1|ensembl:ENSP00000456405.1|ensembl:ENSP00000457870.1	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:lst8_human(display_long)|uniprotkb:MLST8(gene name)|psi-mi:MLST8(display_short)|uniprotkb:GBL(gene name synonym)|uniprotkb:G protein beta subunit-like(gene name synonym)|uniprotkb:LST8(gene name synonym)|uniprotkb:Mammalian lethal with SEC13 protein 8(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"refseq:NP_001186102.1|refseq:NP_001186103.1|refseq:NP_001186104.1|refseq:NP_071767.3|refseq:XP_016879037.1|refseq:XP_016879038.1|dip:DIP-39481N|ensembl:ENSG00000167965.18(gene)|ensembl:ENST00000397124.5(transcript)|ensembl:ENST00000564088.5(transcript)|ensembl:ENST00000565250.1(transcript)|ensembl:ENST00000569417.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0031929""(TOR signaling)|go:""GO:0031931""(TORC1 complex)|go:""GO:0031932""(TORC2 complex)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0038203""(TORC2 signaling)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0046889""(positive regulation of lipid biosynthetic process)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071470""(cellular response to osmotic stress)|go:""GO:1905857""(positive regulation of pentose-phosphate shunt)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR037588|mint:Q9BVC4|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5H64|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|rcsb pdb:7OWG|rcsb pdb:7PE7|rcsb pdb:7PE8|rcsb pdb:7PE9|rcsb pdb:7PEA|rcsb pdb:7PEB|rcsb pdb:7PEC|rcsb pdb:7TZO|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8ERA|rcsb pdb:8RCH|rcsb pdb:8RCK|rcsb pdb:9F44|rcsb pdb:9F45|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|reactome:R-HSA-9856530|panther:PTHR19842(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:BQek96xYe/1IaE8vgX3Uvl9vkCc9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84560	uniprotkb:O75431	intact:EBI-22302898	intact:EBI-7415268|uniprotkb:Q53SQ2|uniprotkb:Q5M7Z6|uniprotkb:A8JZZ4|intact:MINT-3001232|intact:MINT-4876050|uniprotkb:Q53S50|uniprotkb:Q8IZ68|ensembl:ENSP00000249442.6	psi-mi:o84560_chltr(display_long)|uniprotkb:CT_556(locus name)	psi-mi:mtx2_human(display_long)|uniprotkb:MTX2(gene name)|psi-mi:MTX2(display_short)|uniprotkb:Mitochondrial outer membrane import complex protein 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302905|imex:IM-27647-7	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_009872749.1|refseq:NP_220071.1|mint:O84560"	"efo:""Orphanet:647667""|ensembl:ENSG00000128654.14(gene)|ensembl:ENST00000249442.11(transcript)|go:""GO:0001401""(SAM complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006839""(mitochondrial transport)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007007""(inner mitochondrial membrane organization)|go:""GO:0045040""(protein insertion into mitochondrial outer membrane)|go:""GO:0140275""(MIB complex)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|interpro:IPR050931|mint:O75431|reactome:R-HSA-1268020|reactome:R-HSA-8949613|refseq:NP_001006636.1|refseq:NP_001306026.1|refseq:NP_001306027.1|refseq:NP_006545.1|panther:PTHR12289(orthology-group)"	-	-	comment:mint|function:Involved in transport of proteins into the mitochondrion	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/05	rogid:HWARZCf1ho4obz/G1bAIcFr+dIo272561	rogid:M4zfGX8gfFUFW7xYoXeEzA2UCSM9606	intact-crc:BCDA4357A1A09911|rigid:fi73t3qDZaT0g5UmlmS123cVABM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:O60293	intact:EBI-22302928	intact:EBI-746701|ensembl:ENSP00000368017.4|intact:EBI-2874127|uniprotkb:Q6GMU1|uniprotkb:Q6P2S9|uniprotkb:Q6ZV36|uniprotkb:Q96BE7	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:zc3h1_human(display_long)|uniprotkb:Proline/serine-rich coiled-coil protein 2(gene name synonym)|uniprotkb:ZFC3H1(gene name)|psi-mi:ZFC3H1(display_short)|uniprotkb:KIAA0546(gene name synonym)|uniprotkb:PSRC2(gene name synonym)|uniprotkb:CCDC131(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 131(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"ensembl:ENSG00000133858.17(gene)|ensembl:ENST00000378743.9(transcript)|go:""GO:0000176""(""nuclear exosome (RNase complex)"")|go:""GO:0000178""(""exosome (RNase complex)"")|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0006396""(RNA processing)|go:""GO:0046872""(metal ion binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019607|interpro:IPR039278|mint:O60293|refseq:NP_659419.3|panther:PTHR21563(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:QJlOZNAOi6leWMDpXLZH6hYjMOk9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q12770	intact:EBI-22302928	intact:EBI-6190187|uniprotkb:Q8N2E0|uniprotkb:Q8WUA1|ensembl:ENSP00000265565.5|ensembl:ENSP00000497087.1	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:scap_human(display_long)|uniprotkb:SCAP(gene name)|psi-mi:SCAP(display_short)|uniprotkb:KIAA0199(gene name synonym)|uniprotkb:PSEC0227(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:XP_011531803.1|refseq:NP_036367.2|refseq:XP_016861407.1|refseq:XP_016861410.1|ensembl:ENSG00000114650.21(gene)|ensembl:ENST00000265565.10(transcript)|ensembl:ENST00000648151.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001666""(response to hypoxia)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006955""(immune response)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0032868""(response to insulin)|go:""GO:0032933""(SREBP signaling pathway)|go:""GO:0032934""(sterol binding)|go:""GO:0032936""(SREBP-SCAP complex)|go:""GO:0033552""(response to vitamin B3)|go:""GO:0042304""(regulation of fatty acid biosynthetic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045540""(regulation of cholesterol biosynthetic process)|go:""GO:0045541""(negative regulation of cholesterol biosynthetic process)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR030225|interpro:IPR036322|interpro:IPR053958|mint:Q12770|rcsb pdb:6M49|rcsb pdb:7ETW|reactome:R-HSA-1655829|panther:PTHR46378(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:bhavwLS6XzkZpAoBhCsII97JfpI9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q27J81	intact:EBI-22302928	intact:EBI-2557882|uniprotkb:Q6PK22|uniprotkb:Q86TR7|uniprotkb:Q9H6N1|uniprotkb:Q9BRM1|uniprotkb:Q27J83|uniprotkb:Q69YL8|uniprotkb:Q6P1X7|intact:EBI-28987364|ensembl:ENSP00000376410.4	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:inf2_human(display_long)|uniprotkb:INF2(gene name)|psi-mi:INF2(display_short)|uniprotkb:C14orf151(gene name synonym)|uniprotkb:C14orf173(gene name synonym)|uniprotkb:HBEBP2-binding protein C(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"efo:""Orphanet:656""|efo:""Orphanet:93114""|ensembl:ENSG00000203485.14(gene)|ensembl:ENST00000392634.9(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005884""(actin filament)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0090140""(regulation of mitochondrial fission)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:Q27J81|rcsb pdb:8RV2|rcsb pdb:9AZ4|rcsb pdb:9AZP|rcsb pdb:9AZQ|rcsb pdb:9B03|rcsb pdb:9B0K|rcsb pdb:9FJN|rcsb pdb:9FJW|refseq:NP_001026884.3|refseq:NP_071934.3|refseq:NP_116103.1|panther:PTHR45691(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:Vtx6fZtKGr2qGWX70naf5REXWTw9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:O75155	intact:EBI-22302928	intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641.2	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712.13(gene)|ensembl:ENST00000456430.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0010265""(SCF complex assembly)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017025""(TBP-class protein binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013932(""TATA-binding protein interacting (TIP20)"")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155|panther:PTHR12696(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q9NSV4	intact:EBI-22302928	intact:EBI-1050601|uniprotkb:A2A3B8|uniprotkb:A2A3B9|uniprotkb:A2A3C0|uniprotkb:Q18P99|uniprotkb:Q18PA0|uniprotkb:Q18PA1|uniprotkb:Q2KPB6|uniprotkb:Q3ZK23|uniprotkb:Q5JTP8|uniprotkb:Q5T2S7|uniprotkb:Q5XKF6|uniprotkb:Q6MZF0|uniprotkb:Q6NUP0|uniprotkb:Q86VS4|uniprotkb:Q8NAV4|ensembl:ENSP00000383178.3	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:diap3_human(display_long)|uniprotkb:Diaphanous-related formin-3(gene name synonym)|uniprotkb:DIAPH3(gene name)|psi-mi:DIAPH3(display_short)|uniprotkb:DIAP3(gene name synonym)|uniprotkb:MDia2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"efo:""Orphanet:90635""|rcsb pdb:5UWP|ensembl:ENSG00000139734.19(gene)|ensembl:ENST00000400324.9(transcript)|go:""GO:0000813""(ESCRT I complex)|go:""GO:0000922""(spindle pole)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003779""(actin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|rcsb pdb:6X2Y|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007026""(negative regulation of microtubule depolymerization)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008017""(microtubule binding)|go:""GO:0010467""(gene expression)|go:""GO:0016197""(endosomal transport)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030030""(cell projection organization)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031941""(filamentous actin)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034367""(protein-containing complex remodeling)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043131""(erythrocyte enucleation)|go:""GO:0045010""(actin nucleation)|go:""GO:0045296""(cadherin binding)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060113""(inner ear receptor cell differentiation)|go:""GO:0060322""(head development)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:0071800""(podosome assembly)|go:""GO:0097470""(ribbon synapse)|go:""GO:1990427""(stereocilia tip-link density)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|interpro:IPR044933|interpro:IPR051412|mint:Q9NSV4|reactome:R-HSA-5663220|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|refseq:NP_001035982.1|refseq:NP_001245295.1|refseq:NP_001245296.1|refseq:NP_001245297.1|refseq:NP_001245298.1|refseq:NP_001245299.1|refseq:NP_112194.2|panther:PTHR45691(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:noy8LGt6F+8an19X1WyEqSqpAYk9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q86XI2	intact:EBI-22302928	intact:EBI-1047404|uniprotkb:Q7Z3J9|uniprotkb:Q8WUG8|uniprotkb:Q9BRX6|uniprotkb:Q9H8S2|uniprotkb:Q9H9K6|uniprotkb:A4D228|ensembl:ENSP00000348657.3|ensembl:ENSP00000386569.1	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:cndg2_human(display_long)|uniprotkb:Chromosome-associated protein G2(gene name synonym)|uniprotkb:Non-SMC condensin II complex subunit G2(gene name synonym)|uniprotkb:Leucine zipper protein 5(gene name synonym)|uniprotkb:NCAPG2(gene name)|psi-mi:NCAPG2(display_short)|uniprotkb:LUZP5(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_060230.5|ensembl:ENSG00000146918.20(gene)|ensembl:ENST00000356309.8(transcript)|ensembl:ENST00000409423.5(transcript)|go:""GO:0000070""(mitotic sister chromatid segregation)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000796""(condensin complex)|go:""GO:0001833""(inner cell mass cell proliferation)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030261""(chromosome condensation)|go:""GO:0035064""(methylated histone binding)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0051301""(cell division)|go:""GO:0051984""(positive regulation of chromosome segregation)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:1905821""(positive regulation of chromosome condensation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024741|mint:Q86XI2|reactome:R-HSA-2299718|refseq:NP_001268861.1|refseq:NP_001268862.1|refseq:XP_011514658.1|refseq:XP_011514659.1|dip:DIP-43902N|panther:PTHR16199(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:4JkTPdyKz1cYblG0ZU0vQKMsuB49606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:P78347	intact:EBI-22302928	intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070.1	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"efo:""Orphanet:904""|ensembl:ENSG00000263001.8(gene)|ensembl:ENST00000573035.6(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|interpro:IPR036647|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|refseq:NP_001157108.1|refseq:NP_001267729.1|refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|dip:DIP-24252N|panther:PTHR46304(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q7Z4Q2	intact:EBI-22302928	intact:EBI-1051903|uniprotkb:Q8N525|uniprotkb:Q8WV56|uniprotkb:Q96CC9|uniprotkb:Q9NWN7|ensembl:ENSP00000299192.7|uniprotkb:A8K1N4	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:heat3_human(display_long)|uniprotkb:HEATR3(gene name)|psi-mi:HEATR3(display_short)|uniprotkb:Symportin Syo1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"ensembl:ENSG00000155393.14(gene)|ensembl:ENST00000299192.8(transcript)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0043249""(erythrocyte maturation)|go:""GO:0051082""(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR052616|mint:Q7Z4Q2|refseq:NP_891552.1|efo:""Orphanet:124""|panther:PTHR13347(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:CjdYLKIHc/A29+XYy4VjNNHJSRU9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q86U38	intact:EBI-22302928	intact:EBI-5456022|uniprotkb:Q8IVF0|uniprotkb:Q8TBS6|intact:EBI-8293740|intact:MINT-8407174|uniprotkb:A8MY76|ensembl:ENSP00000267425.3|ensembl:ENSP00000495668.1	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:nop9_human(display_long)|uniprotkb:NOP9(gene name)|psi-mi:NOP9(display_short)|uniprotkb:C14orf21(gene name synonym)|uniprotkb:KIAA2021(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_001273296.1|refseq:NP_777573.1|ensembl:ENSG00000196943.14(gene)|ensembl:ENSG00000285326.3(gene)|ensembl:ENST00000267425.8(transcript)|ensembl:ENST00000644840.2(transcript)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0000447""(""endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0000472""(""endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0000480""(""endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0003723""(RNA binding)|go:""GO:0005730""(nucleolus)|go:""GO:0030686""(90S preribosome)|go:""GO:0030688""(preribosome, small subunit precursor)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040000|mint:Q86U38|panther:PTHR13102(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:dJjEtwyK4x6qVx2dW0MzS7tqDYI9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q6IBW4	intact:EBI-22302928	intact:EBI-2548296|uniprotkb:Q9BUT3|uniprotkb:Q9BVD1|uniprotkb:B7WPH1|uniprotkb:O43788|uniprotkb:Q13391|uniprotkb:Q96C14|uniprotkb:Q96GJ0|uniprotkb:Q9BQ71|ensembl:ENSP00000410088.2	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:cndh2_human(display_long)|uniprotkb:NCAPH2(gene name)|psi-mi:NCAPH2(display_short)|uniprotkb:CAPH2(gene name synonym)|uniprotkb:Non-SMC condensin II complex subunit H2(gene name synonym)|uniprotkb:Chromosome-associated protein H2(gene name synonym)|uniprotkb:Kleisin-beta(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_001171940.1|refseq:NP_055366.3|refseq:NP_689512.2|ensembl:ENSG00000025770.19(gene)|ensembl:ENST00000420993.7(transcript)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000796""(condensin complex)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007076""(mitotic chromosome condensation)|go:""GO:0010032""(meiotic chromosome condensation)|go:""GO:0016020""(membrane)|go:""GO:0030054""(cell junction)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0045171""(intercellular bridge)|go:""GO:0051306""(mitotic sister chromatid separation)|go:""GO:0051309""(female meiosis chromosome separation)|go:""GO:0051984""(positive regulation of chromosome segregation)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:1905821""(positive regulation of chromosome condensation)|interpro:IPR009378(Protein of unknown function DUF1032)|interpro:IPR031719|interpro:IPR031737|interpro:IPR031739|mint:Q6IBW4|reactome:R-HSA-2299718|dip:DIP-43901N|panther:PTHR14324(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:GTOZg0OoAHm+tj3C8/3sCGM+G5E9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q9BT22	intact:EBI-22302928	intact:EBI-6268721|uniprotkb:Q6UVZ9|uniprotkb:Q8N5Y4|uniprotkb:Q9P2Y2|uniprotkb:B4DP08|ensembl:ENSP00000262374.5	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	"psi-mi:alg1_human(display_long)|uniprotkb:ALG1(gene name)|psi-mi:ALG1(display_short)|uniprotkb:HMAT1(gene name synonym)|uniprotkb:HMT1(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 1 homolog(gene name synonym)|uniprotkb:Beta-1,4-mannosyltransferase(gene name synonym)|uniprotkb:""GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase""(gene name synonym)|uniprotkb:GDP-mannose-dolichol diphosphochitobiose mannosyltransferase(gene name synonym)|uniprotkb:Mannosyltransferase-1(gene name synonym)|uniprotkb:PSEC0061(orf name)|uniprotkb:UNQ861/PRO1870(orf name)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"ensembl:ENSG00000033011.14(gene)|ensembl:ENST00000262374.10(transcript)|go:""GO:0000030""(mannosyltransferase activity)|go:""GO:0004578""(chitobiosyldiphosphodolichol beta-mannosyltransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0006488""(dolichol-linked oligosaccharide biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR026051|mint:Q9BT22|reactome:R-HSA-446193|reactome:R-HSA-4549380|refseq:NP_001317433.1|refseq:NP_061982.3|refseq:XP_016878947.1|efo:""Orphanet:79327""|panther:PTHR13036(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:ssuj2ltO7juusnd1BHWPqAsYdV09606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:P56182	intact:EBI-22302928	intact:EBI-2880285|uniprotkb:Q9NST5|ensembl:ENSP00000417464.1	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_003674.1|ensembl:ENSG00000160214.13(gene)|ensembl:ENST00000497547.2(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0006364""(rRNA processing)|go:""GO:0030688""(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|rcsb pdb:8FKP|rcsb pdb:8FKR|rcsb pdb:8FKT|rcsb pdb:8FKV|reactome:R-HSA-6791226|panther:PTHR13026(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:P55010	intact:EBI-22302928	intact:EBI-286450|uniprotkb:Q9H5N2|uniprotkb:Q9UG48|uniprotkb:Q53XB3|ensembl:ENSP00000216554.3|ensembl:ENSP00000376477.2|ensembl:ENSP00000453743.1	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:if5_human(display_long)|uniprotkb:EIF5(gene name)|psi-mi:EIF5(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_001960.2|refseq:NP_892116.2|ensembl:ENSG00000100664.11(gene)|ensembl:ENST00000216554.8(transcript)|ensembl:ENST00000392715.6(transcript)|ensembl:ENST00000558506.1(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005092""(GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0042255""(ribosome assembly)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0071074""(eukaryotic initiation factor eIF2 binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|interpro:IPR045196|mint:P55010|rcsb pdb:2E9H|rcsb pdb:2G2K|rcsb pdb:2IU1|rcsb pdb:8OZ0|rcsb pdb:8PJ2|rcsb pdb:8PJ3|reactome:R-HSA-72702|reactome:R-HSA-72706|panther:PTHR23001(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:lM5AZJWJOQGbxADfl8MGCx3JAXc9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q86UD0	intact:EBI-22302928	intact:EBI-2561646|ensembl:ENSP00000386348.3	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:sapc2_human(display_long)|uniprotkb:SAPCD2(gene name)|psi-mi:SAPCD2(display_short)|uniprotkb:C9orf140(gene name synonym)|uniprotkb:Tumor specificity and mitosis phase-dependent expression protein(gene name synonym)|uniprotkb:p42.3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_848543.2|ensembl:ENSG00000186193.9(gene)|ensembl:ENST00000409687.5(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0043296""(apical junction complex)|go:""GO:0045179""(apical cortex)|go:""GO:0090175""(regulation of establishment of planar polarity)|go:""GO:0098725""(symmetric cell division)|go:""GO:1904777""(negative regulation of protein localization to cell cortex)|interpro:IPR026828|mint:Q86UD0|panther:PTHR14907(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:P07CYw5xvvMZxL3MdRzOVP1fLQg9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:P42695	intact:EBI-22302928	intact:EBI-722805|uniprotkb:A6NFS2|uniprotkb:Q4KMQ9|ensembl:ENSP00000433681.3|ensembl:ENSP00000508707.1|ensembl:ENSP00000510391.1	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:cndd3_human(display_long)|uniprotkb:Non-SMC condensin II complex subunit D3(gene name synonym)|uniprotkb:NCAPD3(gene name)|psi-mi:NCAPD3(display_short)|uniprotkb:CAPD3(gene name synonym)|uniprotkb:KIAA0056(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"efo:""Orphanet:2512""|ensembl:ENSG00000151503.14(gene)|ensembl:ENST00000534548.7(transcript)|ensembl:ENST00000685324.1(transcript)|ensembl:ENST00000688672.1(transcript)|go:""GO:0000779""(condensed chromosome, centromeric region)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000796""(condensin complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0007076""(mitotic chromosome condensation)|go:""GO:0010032""(meiotic chromosome condensation)|go:""GO:0016020""(membrane)|go:""GO:0035064""(methylated histone binding)|go:""GO:0042393""(histone binding)|go:""GO:0051301""(cell division)|go:""GO:0051984""(positive regulation of chromosome segregation)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:1905821""(positive regulation of chromosome condensation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|interpro:IPR032682|mint:P42695|reactome:R-HSA-2299718|refseq:NP_056076.1|dip:DIP-43903N|panther:PTHR14222(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:z5WYLlrGt33uAM9NRN9SQeHFDaA9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q86VP6	intact:EBI-22302928	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318.1	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_060918.2|ensembl:ENSG00000111530.13(gene)|ensembl:ENST00000545606.6(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0010265""(SCF complex assembly)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017025""(TBP-class protein binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031461""(cullin-RING ubiquitin ligase complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0045899""(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013932(""TATA-binding protein interacting (TIP20)"")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|rcsb pdb:7Z8R|rcsb pdb:7Z8T|rcsb pdb:7Z8V|rcsb pdb:7ZBW|rcsb pdb:7ZBZ|rcsb pdb:8CDJ|rcsb pdb:8CDK|rcsb pdb:8H3Q|rcsb pdb:8OR0|rcsb pdb:8OR2|rcsb pdb:8OR3|rcsb pdb:8OR4|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|dip:DIP-31608N|panther:PTHR12696(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:O95347	intact:EBI-22302928	intact:EBI-355822|intact:EBI-1058371|uniprotkb:Q9P1P2|uniprotkb:Q6IEE0|intact:EBI-25598637|ensembl:ENSP00000286398.7|ensembl:ENSP00000363919.3|ensembl:ENSP00000363925.3	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:smc2_human(display_long)|uniprotkb:PRO0324(orf name)|uniprotkb:SMC2(gene name)|psi-mi:SMC2(display_short)|uniprotkb:CAPE(gene name synonym)|uniprotkb:SMC2L1(gene name synonym)|uniprotkb:Chromosome-associated protein E(gene name synonym)|uniprotkb:XCAP-E homolog(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_001036015.1|refseq:NP_001036016.1|refseq:NP_006435.2|refseq:XP_011516451.1|refseq:XP_011516455.1|refseq:NP_001252531.1|ensembl:ENSG00000136824.19(gene)|ensembl:ENST00000286398.11(transcript)|ensembl:ENST00000374787.7(transcript)|ensembl:ENST00000374793.8(transcript)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000785""(chromatin)|go:""GO:0000793""(condensed chromosome)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000796""(condensin complex)|go:""GO:0003682""(chromatin binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007076""(mitotic chromosome condensation)|go:""GO:0010032""(meiotic chromosome condensation)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045132""(meiotic chromosome segregation)|go:""GO:0051301""(cell division)|go:""GO:0051383""(kinetochore organization)|go:""GO:0051984""(positive regulation of chromosome segregation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:1905821""(positive regulation of chromosome condensation)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027120|interpro:IPR027417|interpro:IPR036277|mint:O95347|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853|refseq:XP_006716996.1|refseq:XP_011516450.1|refseq:XP_016869695.1|refseq:XP_016869696.1|refseq:XP_016869697.1|dip:DIP-35422N|panther:PTHR43941(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:k7RHRDmgiucuAOIfh8vjbqnlv3E9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q9UHI6	intact:EBI-22302928	intact:EBI-347658|ensembl:ENSP00000358716.4|ensembl:ENSP00000505857.1|uniprotkb:Q9UIY0|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9Y659|uniprotkb:B4DWV7	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"ensembl:ENSG00000064703.13(gene)|ensembl:ENST00000369702.5(transcript)|ensembl:ENST00000679724.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000244""(spliceosomal tri-snRNP complex assembly)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006396""(RNA processing)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032797""(SMN complex)|go:""GO:0034719""(SMN-Sm protein complex)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0048477""(oogenesis)|go:""GO:0050810""(regulation of steroid biosynthetic process)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0090571""(RNA polymerase II transcription repressor complex)|go:""GO:0097504""(Gemini of Cajal bodies)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|reactome:R-HSA-9754678|refseq:NP_009135.4|dip:DIP-32606N|panther:PTHR47958(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q07065	intact:EBI-22302928	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265.4|intact:EBI-21353377	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_006816.2|ensembl:ENSG00000136026.14(gene)|ensembl:ENST00000378026.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005811""(lipid droplet)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042599""(lamellar body)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270|panther:PTHR45161(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q96HR8	intact:EBI-22302928	intact:EBI-2515597|uniprotkb:D3DP28|ensembl:ENSP00000274054.2|uniprotkb:E9PAZ2	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:naf1_human(display_long)|uniprotkb:NAF1(gene name)|psi-mi:NAF1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:XP_011530712.1|refseq:NP_001122403.1|refseq:NP_612395.2|ensembl:ENSG00000145414.9(gene)|ensembl:ENST00000274054.3(transcript)|go:""GO:0000454""(snoRNA guided rRNA pseudouridine synthesis)|go:""GO:0000493""(box H/ACA snoRNP assembly)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005732""(""sno(s)RNA-containing ribonucleoprotein complex"")|go:""GO:0005737""(cytoplasm)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043489""(RNA stabilization)|go:""GO:0070034""(telomerase RNA binding)|go:""GO:0090669""(telomerase RNA stabilization)|go:""GO:0090671""(telomerase RNA localization to Cajal body)|go:""GO:1904358""(positive regulation of telomere maintenance via telomere lengthening)|go:""GO:1905323""(telomerase holoenzyme complex assembly)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|interpro:IPR040309|mint:Q96HR8|rcsb pdb:2EQN|panther:PTHR31633(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:RN78Bx9nJvfGDvaezT/U4TUf2KY9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:P04637	intact:EBI-22302928	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5|ensembl:ENSP00000269305.4|ensembl:ENSP00000391478.2|ensembl:ENSP00000424104.2|ensembl:ENSP00000426252.2|ensembl:ENSP00000519624.1|ensembl:ENSP00000519626.1	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"efo:""Orphanet:1333""|efo:""Orphanet:145""|efo:""Orphanet:1501""|efo:""Orphanet:210159""|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:251899""|efo:""Orphanet:2807""|efo:""Orphanet:293199""|efo:""Orphanet:3318""|efo:""Orphanet:524""|efo:""Orphanet:585909""|efo:""Orphanet:668""|efo:""Orphanet:67038""|efo:""Orphanet:70573""|efo:""Orphanet:96253""|efo:""Orphanet:99756""|efo:""Orphanet:99757""|panther:PTHR11447(orthology-group)|efo:""Orphanet:52688""|ensembl:ENSG00000141510.19(gene)|ensembl:ENST00000269305.9(transcript)|ensembl:ENST00000445888.6(transcript)|ensembl:ENST00000503591.2(transcript)|ensembl:ENST00000508793.6(transcript)|ensembl:ENST00000714357.1(transcript)|ensembl:ENST00000714359.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000423""(mitophagy)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001094""(TFIID-class transcription factor complex binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001756""(somitogenesis)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0002020""(protease binding)|go:""GO:0002039""(p53 binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002309""(T cell proliferation involved in immune response)|go:""GO:0002326""(B cell lineage commitment)|go:""GO:0002360""(T cell lineage commitment)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005507""(copper ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005657""(replication fork)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006914""(autophagy)|go:""GO:0006974""(DNA damage response)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0006978""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:0006983""(ER overload response)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007369""(gastrulation)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007406""(negative regulation of neuroblast proliferation)|go:""GO:0008104""(protein localization)|go:""GO:0008156""(negative regulation of DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0009299""(mRNA transcription)|go:""GO:0009303""(rRNA transcription)|go:""GO:0009651""(response to salt stress)|go:""GO:0010165""(response to X-ray)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010659""(cardiac muscle cell apoptotic process)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016032""(viral process)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016605""(PML body)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019661""(glucose catabolic process to lactate via pyruvate)|go:""GO:0019899""(enzyme binding)|go:""GO:0021549""(cerebellum development)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034103""(regulation of tissue remodeling)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035033""(histone deacetylase regulator activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035794""(positive regulation of mitochondrial membrane permeability)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036310""(ATP-dependent DNA/DNA annealing activity)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043073""(germ cell nucleus)|go:""GO:0043153""(entrainment of circadian clock by photoperiod)|go:""GO:0043504""(mitochondrial DNA repair)|go:""GO:0043516""(regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045899""(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048512""(circadian behavior)|go:""GO:0048539""(bone marrow development)|go:""GO:0048568""(embryonic organ development)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051097""(negative regulation of helicase activity)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051276""(chromosome organization)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070242""(thymocyte apoptotic process)|go:""GO:0070245""(positive regulation of thymocyte apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071494""(cellular response to UV-C)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0072331""(signal transduction by p53 class mediator)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0072717""(cellular response to actinomycin D)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090399""(replicative senescence)|go:""GO:0090403""(oxidative stress-induced premature senescence)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097252""(oligodendrocyte apoptotic process)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901525""(negative regulation of mitophagy)|go:""GO:1902108""(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902253""(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:1902749""(regulation of cell cycle G2/M phase transition)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903451""(negative regulation of G1 to G0 transition)|go:""GO:1903799""(negative regulation of miRNA processing)|go:""GO:1904024""(negative regulation of glucose catabolic process to lactate via pyruvate)|go:""GO:1905856""(negative regulation of pentose-phosphate shunt)|go:""GO:1990144""(intrinsic apoptotic signaling pathway in response to hypoxia)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000269""(regulation of fibroblast apoptotic process)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2000647""(negative regulation of stem cell proliferation)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872(""p53 transactivation domain (TAD)"")|interpro:IPR036674|interpro:IPR040926|mint:P04637|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|rcsb pdb:2AHI|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3Q06|rcsb pdb:3SAK|rcsb pdb:3TG5|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGL|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:5BUA|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6XRE|rcsb pdb:6ZNC|rcsb pdb:7B46|rcsb pdb:7B47|rcsb pdb:7B48|rcsb pdb:7B49|rcsb pdb:7B4A|rcsb pdb:7B4B|rcsb pdb:7B4C|rcsb pdb:7B4D|rcsb pdb:7B4E|rcsb pdb:7B4F|rcsb pdb:7B4G|rcsb pdb:7B4H|rcsb pdb:7B4N|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7DVD|rcsb pdb:7EAX|rcsb pdb:7EDS|rcsb pdb:7EEU|rcsb pdb:7EL4|rcsb pdb:7NMI|rcsb pdb:7RM4|rcsb pdb:7V97|rcsb pdb:7XZX|rcsb pdb:7XZZ|rcsb pdb:7YGI|rcsb pdb:8A31|rcsb pdb:8A32|rcsb pdb:8A92|rcsb pdb:8CG7|rcsb pdb:8DC4|rcsb pdb:8DC6|rcsb pdb:8DC7|rcsb pdb:8DC8|rcsb pdb:8E7A|rcsb pdb:8E7B|rcsb pdb:8F2H|rcsb pdb:8F2I|rcsb pdb:8GCR|rcsb pdb:8HLL|rcsb pdb:8HLM|rcsb pdb:8HLN|rcsb pdb:8J8N|rcsb pdb:8OXM|rcsb pdb:8OXO|rcsb pdb:8QWK|rcsb pdb:8QWL|rcsb pdb:8QWM|rcsb pdb:8QWN|rcsb pdb:8QWO|rcsb pdb:8QWP|rcsb pdb:8R1F|rcsb pdb:8R1G|rcsb pdb:8UQR|rcsb pdb:8WD2|rcsb pdb:8XP5|rcsb pdb:9C5S|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-9723905|reactome:R-HSA-9725370|reactome:R-HSA-9758274|reactome:R-HSA-9819196|reactome:R-HSA-983231|reactome:R-HSA-9833482|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|refseq:NP_001119590.1|refseq:NP_001263624.1|refseq:NP_001263625.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|ensembl:ENSP00000269305.4|ensembl:ENST00000420246.6|ensembl:ENSP00000391127.2|ensembl:ENSP00000391478.2|ensembl:ENST00000455263.6|ensembl:ENSP00000398846.2|ensembl:ENSP00000426252.2|ensembl:ENST00000504290.5|ensembl:ENSP00000484409.1|ensembl:ENST00000504937.5|ensembl:ENSP00000481179.1|ensembl:ENSP00000424104.2|ensembl:ENST00000509690.6|ensembl:ENSP00000425104.2|ensembl:ENST00000510385.5|ensembl:ENSP00000478499.1|ensembl:ENST00000610292.4|ensembl:ENSP00000478219.1|ensembl:ENST00000610538.4|ensembl:ENSP00000480868.1|ensembl:ENST00000619485.4|ensembl:ENSP00000482537.1|ensembl:ENST00000620739.4|ensembl:ENSP00000481638.1|ensembl:ENST00000622645.4|ensembl:ENSP00000482222.1|ensembl:ENSP00000519624.1|ensembl:ENSP00000519626.1"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q9H4A6	intact:EBI-22302928	intact:EBI-2465479|uniprotkb:Q9UIW5|ensembl:ENSP00000265070.6	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:golp3_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short)|uniprotkb:GPP34(gene name synonym)|uniprotkb:Coat protein GPP34(gene name synonym)|uniprotkb:Mitochondrial DNA absence factor(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"refseq:NP_071413.1|ensembl:ENSG00000113384.14(gene)|ensembl:ENST00000265070.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0009101""(glycoprotein biosynthetic process)|go:""GO:0009306""(protein secretion)|go:""GO:0010467""(gene expression)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0016477""(cell migration)|go:""GO:0019899""(enzyme binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0031985""(Golgi cisterna)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045053""(protein retention in Golgi apparatus)|go:""GO:0048194""(Golgi vesicle budding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0060352""(cell adhesion molecule production)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0072752""(cellular response to rapamycin)|go:""GO:0090161""(Golgi ribbon formation)|go:""GO:0090164""(asymmetric Golgi ribbon formation)|go:""GO:0140312""(cargo adaptor activity)|go:""GO:0140450""(protein targeting to Golgi apparatus)|interpro:IPR008628(Golgi phosphoprotein 3)|interpro:IPR038261|mint:Q9H4A6|rcsb pdb:3KN1|panther:PTHR12704(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:tHHREhHksCP+Yf9FzycM9cI+wkc9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:Q8WXD5	intact:EBI-22302928	intact:EBI-752301|ensembl:ENSP00000281950.2|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"ensembl:ENSG00000152147.11(gene)|ensembl:ENST00000281950.8(transcript)|go:""GO:0000245""(spliceosomal complex assembly)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016604""(nuclear body)|go:""GO:0032797""(SMN complex)|go:""GO:0034719""(SMN-Sm protein complex)|go:""GO:0097504""(Gemini of Cajal bodies)|interpro:IPR009422(Gemin6)|interpro:IPR046856|interpro:IPR046857|interpro:IPR047574|interpro:IPR047575|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859|reactome:R-HSA-9754678|refseq:NP_079051.9|dip:DIP-41331N|panther:PTHR14710(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84793	uniprotkb:O60610	intact:EBI-22302928	intact:EBI-3959709|uniprotkb:Q59FH8|uniprotkb:B7ZKW2|uniprotkb:A6NF18|uniprotkb:Q9UC76|intact:EBI-6137912|uniprotkb:E9PEZ2|uniprotkb:Q17RN4|ensembl:ENSP00000373706.4	psi-mi:o84793_chltr(display_long)|uniprotkb:CT_788(locus name)	psi-mi:diap1_human(display_long)|uniprotkb:DIAPH1(gene name)|psi-mi:DIAPH1(display_short)|uniprotkb:DIAP1(gene name synonym)|uniprotkb:Diaphanous-related formin-1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302936|imex:IM-27647-91	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|interpro:IPR025640|refseq:NP_220307.1|refseq:WP_010725345.1|mint:O84793"	"ensembl:ENSG00000131504.18(gene)|ensembl:ENST00000389054.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032886""(regulation of microtubule-based process)|go:""GO:0035372""(protein localization to microtubule)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0071420""(cellular response to histamine)|go:""GO:0072686""(mitotic spindle)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|interpro:IPR044933|interpro:IPR051412|mint:O60610|rcsb pdb:8FG1|reactome:R-HSA-5663220|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9854909|refseq:NP_001073280.1|refseq:NP_005210.3|efo:""Orphanet:2573""|efo:""Orphanet:477814""|efo:""Orphanet:494444""|panther:PTHR45691(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/20	rogid:a6EHGzyAZxua7c8Pvsx9pDHVI8w272561	rogid:m8uSwdWB9ePt8wzBRQBVujfEBfo9606	intact-crc:C5483027E52C4937|rigid:dyi93G0CJxGxBDN+i9ubprFzfzI	false	strep tag:c-c|binding-associated region:26-166	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84447	uniprotkb:Q9Y3E0	intact:EBI-22303381	intact:EBI-4402607|uniprotkb:B2R4R4|uniprotkb:Q54A40|uniprotkb:Q6I9W6|uniprotkb:Q9P1R9|ensembl:ENSP00000229314.4	psi-mi:o84447_chltr(display_long)|uniprotkb:CT_440(locus name)	psi-mi:got1b_human(display_long)|uniprotkb:GOLT1B(gene name)|psi-mi:GOLT1B(display_short)|uniprotkb:GOT1A(gene name synonym)|uniprotkb:Golgi transport 1 homolog B(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 470(gene name synonym)|uniprotkb:hGOT1a(gene name synonym)|uniprotkb:CGI-141(orf name)|uniprotkb:HDCMA39P(orf name)|uniprotkb:UNQ432/PRO793(orf name)|uniprotkb:GCT2(gene name synonym)|uniprotkb:Germ cell tumor 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303388|imex:IM-27647-69	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_219952.1|refseq:WP_009871795.1|mint:O84447"	"refseq:NP_057156.1|ensembl:ENSG00000111711.10(gene)|ensembl:ENST00000229314.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|interpro:IPR007305(Got1-like protein)|interpro:IPR045176|mint:Q9Y3E0|panther:PTHR21493(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:gu5tPovGP6iBBdfPTQozB6nZ8xQ272561	rogid:dvlUtRzzjPZ9BTUtxhy2Sb3KB4Q9606	intact-crc:17DB42B37204192E|rigid:7M2ieNq9C07a24Xb5uO97mNPE9c	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84449	uniprotkb:Q9NR09	intact:EBI-22303394	intact:EBI-1765160|uniprotkb:Q9ULD1|ensembl:ENSP00000393596.2	psi-mi:srpd_chltr(display_long)|uniprotkb:15 kDa cysteine-rich outer membrane protein(gene name synonym)|uniprotkb:Cysteine-rich protein A(gene name synonym)|uniprotkb:srp(gene name)|psi-mi:srp(display_short)|uniprotkb:crpA(gene name synonym)|uniprotkb:CT_442(locus name)	psi-mi:birc6_human(display_long)|uniprotkb:Baculoviral IAP repeat-containing protein 6(gene name synonym)|uniprotkb:BIRC6(gene name)|psi-mi:BIRC6(display_short)|uniprotkb:KIAA1289(gene name synonym)|uniprotkb:Ubiquitin-conjugating BIR domain enzyme apollon(gene name synonym)|uniprotkb:BIR repeat-containing ubiquitin-conjugating enzyme(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303405|imex:IM-27647-9	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0019867""(outer membrane)|refseq:NP_219954.1|refseq:WP_009872659.1|interpro:IPR008436(Chlamydia 15 kDa cysteine-rich outer membrane)|mint:O84449"	"refseq:NP_057336.3|ensembl:ENSG00000115760.16(gene)|ensembl:ENST00000421745.7(transcript)|go:""GO:0000922""(spindle pole)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030496""(midbody)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0060711""(labyrinthine layer development)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0090543""(Flemming body)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022103|mint:Q9NR09|rcsb pdb:3CEG|rcsb pdb:8ATM|rcsb pdb:8ATO|rcsb pdb:8ATU|rcsb pdb:8ATX|rcsb pdb:8AUK|rcsb pdb:8AUW|rcsb pdb:8E2D|rcsb pdb:8E2E|rcsb pdb:8E2F|rcsb pdb:8E2G|rcsb pdb:8E2H|rcsb pdb:8E2I|rcsb pdb:8E2K|reactome:R-HSA-9700645|reactome:R-HSA-9725370|panther:PTHR46116(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:/Tyk9fBlumPf1mfHsWYTn13A2wQ272561	rogid:VCOEh/W7S7TLU/gNXfg9SkQMhoc9606	intact-crc:9FFC7BBD27005AEB|rigid:z2taWkMhvEFvmFIYRPotXkL4pbE	false	binding-associated region:71-150|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84449	uniprotkb:Q9Y4L1	intact:EBI-22303394	intact:EBI-1054186|uniprotkb:Q2I204|uniprotkb:Q53H25|uniprotkb:B7Z909|uniprotkb:A8C1Z0|ensembl:ENSP00000431874.2|ensembl:ENSP00000462951.2|ensembl:ENSP00000480150.1|ensembl:ENSP00000480248.2|ensembl:ENSP00000486825.1	psi-mi:srpd_chltr(display_long)|uniprotkb:15 kDa cysteine-rich outer membrane protein(gene name synonym)|uniprotkb:Cysteine-rich protein A(gene name synonym)|uniprotkb:srp(gene name)|psi-mi:srp(display_short)|uniprotkb:crpA(gene name synonym)|uniprotkb:CT_442(locus name)	psi-mi:hyou1_human(display_long)|uniprotkb:HSPH4(gene name synonym)|uniprotkb:Heat shock protein family H member 4(gene name synonym)|uniprotkb:150 kDa oxygen-regulated protein(gene name synonym)|uniprotkb:GRP170(gene name synonym)|uniprotkb:HYOU1(gene name)|psi-mi:HYOU1(display_short)|uniprotkb:ORP150(gene name synonym)|uniprotkb:170 kDa glucose-regulated protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303405|imex:IM-27647-9	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0019867""(outer membrane)|refseq:NP_219954.1|refseq:WP_009872659.1|interpro:IPR008436(Chlamydia 15 kDa cysteine-rich outer membrane)|mint:O84449"	"refseq:NP_001124463.1|refseq:NP_006380.1|refseq:XP_016872585.1|refseq:XP_016872586.1|ensembl:ENSG00000149428.21(gene)|ensembl:ENSG00000280682.3(gene)|ensembl:ENST00000530473.6(transcript)|ensembl:ENST00000534233.6(transcript)|ensembl:ENST00000614711.5(transcript)|ensembl:ENST00000617285.5(transcript)|ensembl:ENST00000630669.3(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0002931""(response to ischemia)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005925""(focal adhesion)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0016020""(membrane)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1903298""(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:""GO:1903382""(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:Q9Y4L1|reactome:R-HSA-3000484|reactome:R-HSA-381038|panther:PTHR45639(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:/Tyk9fBlumPf1mfHsWYTn13A2wQ272561	rogid:xqSFRaiiHJLNVqgh87tHx9lfnS49606	intact-crc:9FFC7BBD27005AEB|rigid:z2taWkMhvEFvmFIYRPotXkL4pbE	false	binding-associated region:71-150|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84648	uniprotkb:Q14534	intact:EBI-22303572	intact:EBI-3905171|uniprotkb:Q9UEK6|uniprotkb:Q9UNR6|ensembl:ENSP00000265896.5	psi-mi:o84648_chltr(display_long)|uniprotkb:CT_642(locus name)	psi-mi:erg1_human(display_long)|uniprotkb:SQLE(gene name)|psi-mi:SQLE(display_short)|uniprotkb:ERG1(gene name synonym)|uniprotkb:Squalene epoxidase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303579|imex:IM-27647-29	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220160.1|refseq:WP_010725287.1|mint:O84648"	"refseq:NP_003120.2|ensembl:ENSG00000104549.12(gene)|ensembl:ENST00000265896.10(transcript)|go:""GO:0004506""(squalene monooxygenase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016126""(sterol biosynthetic process)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0071949""(FAD binding)|go:""GO:0140042""(lipid droplet formation)|go:""GO:1904614""(response to biphenyl)|interpro:IPR013698(Squalene epoxidase)|interpro:IPR036188|interpro:IPR040125|mint:Q14534|rcsb pdb:6C6N|rcsb pdb:6C6P|rcsb pdb:6C6R|reactome:R-HSA-191273|reactome:R-HSA-2426168|panther:PTHR10835(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:qYRqhfb71UQRiktdWgcoiYBQXTI272561	rogid:jZnV6eRSD75A7YVspfL6SBq8XkA9606	intact-crc:FB59838207728F1A|rigid:P3RQbtPEPUu4WXnXQp/0hA9BwB4	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84648	uniprotkb:Q92930	intact:EBI-22303572	intact:EBI-1760095|uniprotkb:Q9P293|uniprotkb:Q5JPC4|ensembl:ENSP00000312734.4	psi-mi:o84648_chltr(display_long)|uniprotkb:CT_642(locus name)	psi-mi:rab8b_human(display_long)|uniprotkb:RAB8B(gene name)|psi-mi:RAB8B(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303579|imex:IM-27647-29	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220160.1|refseq:WP_010725287.1|mint:O84648"	"refseq:NP_057614.1|ensembl:ENSG00000166128.13(gene)|ensembl:ENST00000321437.9(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005768""(endosome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0010008""(endosome membrane)|go:""GO:0019003""(GDP binding)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030911""(TPR domain binding)|go:""GO:0031346""(positive regulation of cell projection organization)|go:""GO:0032456""(endocytic recycling)|go:""GO:0045046""(protein import into peroxisome membrane)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051286""(cell tip)|go:""GO:0051461""(positive regulation of corticotropin secretion)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0150115""(cell-substrate junction organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050305|mint:Q92930|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR47980(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:qYRqhfb71UQRiktdWgcoiYBQXTI272561	rogid:1EzHoU6jEdli/t9gfwMBDjW3fNI9606	intact-crc:FB59838207728F1A|rigid:P3RQbtPEPUu4WXnXQp/0hA9BwB4	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84648	uniprotkb:Q9ULH0	intact:EBI-22303572	intact:EBI-716681|uniprotkb:A1L4N4|intact:EBI-2798329|uniprotkb:Q6MZU2|uniprotkb:Q9H889|uniprotkb:Q9H9E4|uniprotkb:Q9NT37|uniprotkb:Q9UF42|uniprotkb:Q4VC08|ensembl:ENSP00000256707.4	psi-mi:o84648_chltr(display_long)|uniprotkb:CT_642(locus name)	psi-mi:kdis_human(display_long)|uniprotkb:KIAA1250(gene name synonym)|uniprotkb:KIDINS220(gene name)|psi-mi:KIDINS220(display_short)|uniprotkb:ARMS(gene name synonym)|uniprotkb:Ankyrin repeat-rich membrane-spanning protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303579|imex:IM-27647-29	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220160.1|refseq:WP_010725287.1|mint:O84648"	"ensembl:ENSG00000134313.17(gene)|ensembl:ENST00000256707.8(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016020""(membrane)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0038180""(nerve growth factor signaling pathway)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR011646(KAP P-loop)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036770|interpro:IPR052771|mint:Q9ULH0|reactome:R-HSA-170984|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_065789.1|efo:""Orphanet:521390""|panther:PTHR24116(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:qYRqhfb71UQRiktdWgcoiYBQXTI272561	rogid:0wyaXuvXCqQTlfjuW4TAcIGmdlw9606	intact-crc:FB59838207728F1A|rigid:P3RQbtPEPUu4WXnXQp/0hA9BwB4	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84648	uniprotkb:P42704	intact:EBI-22303572	intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665.7	psi-mi:o84648_chltr(display_long)|uniprotkb:CT_642(locus name)	psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303579|imex:IM-27647-29	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220160.1|refseq:WP_010725287.1|mint:O84648"	"dip:DIP-27543N|ensembl:ENSG00000138095.20(gene)|ensembl:ENST00000260665.12(transcript)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000957""(mitochondrial RNA catabolic process)|go:""GO:0000961""(negative regulation of mitochondrial RNA catabolic process)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0006914""(autophagy)|go:""GO:0008017""(microtubule binding)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0051028""(mRNA transport)|go:""GO:0070129""(regulation of mitochondrial translation)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|rcsb pdb:8ANY|reactome:R-HSA-9836573|refseq:NP_573566.2|efo:""Orphanet:70472""|panther:PTHR46669(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:qYRqhfb71UQRiktdWgcoiYBQXTI272561	rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606	intact-crc:FB59838207728F1A|rigid:P3RQbtPEPUu4WXnXQp/0hA9BwB4	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84648	uniprotkb:Q9GZT3	intact:EBI-22303572	intact:EBI-1050793|uniprotkb:J3KMY7|intact:EBI-10967524|ensembl:ENSP00000450909.1	psi-mi:o84648_chltr(display_long)|uniprotkb:CT_642(locus name)	psi-mi:slirp_human(display_long)|uniprotkb:SLIRP(gene name)|psi-mi:SLIRP(display_short)|uniprotkb:C14orf156(gene name synonym)|uniprotkb:DC23(orf name)|uniprotkb:DC50(orf name)|uniprotkb:PD04872(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303579|imex:IM-27647-29	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220160.1|refseq:WP_010725287.1|mint:O84648"	"refseq:NP_112487.1|refseq:NP_001254792.1|refseq:NP_001254793.1|ensembl:ENSG00000119705.10(gene)|ensembl:ENST00000557342.6(transcript)|go:""GO:0000961""(negative regulation of mitochondrial RNA catabolic process)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007286""(spermatid development)|go:""GO:0007338""(single fertilization)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0036126""(sperm flagellum)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034152|interpro:IPR035979|interpro:IPR052462|mint:Q9GZT3|rcsb pdb:8ANY|reactome:R-HSA-9836573"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:qYRqhfb71UQRiktdWgcoiYBQXTI272561	rogid:8sPWOtmxPTOVlthXwBiIIp/+6go9606	intact-crc:FB59838207728F1A|rigid:P3RQbtPEPUu4WXnXQp/0hA9BwB4	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84623	uniprotkb:P61962	intact:EBI-22303612	intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|uniprotkb:B4E039|ensembl:ENSP00000402312.2|ensembl:ENSP00000483236.1|ensembl:ENSP00000508930.1|ensembl:ENSP00000509006.1	psi-mi:o84623_chltr(display_long)|uniprotkb:CT_618(locus name)	psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303619|imex:IM-27647-11	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220135.1|refseq:WP_010725275.1|mint:O84623"	"panther:PTHR19919(orthology-group)|refseq:NP_005819.3|ensembl:ENSG00000136485.16(gene)|ensembl:ENST00000431926.7(transcript)|ensembl:ENST00000614556.5(transcript)|ensembl:ENST00000686337.1(transcript)|ensembl:ENST00000690417.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR045159|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/28	rogid:jrgFj+3qHniid9gbFfQSpN1v0yg272561	rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606	intact-crc:D12C65F2DCFA3C23|rigid:HYB7/wNAJZwGAdM3NiCnEp+fxls	false	binding-associated region:1-214|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84623	uniprotkb:Q9NR45	intact:EBI-22303612	intact:EBI-709675|uniprotkb:Q8WUV9|uniprotkb:Q9BWS6|uniprotkb:Q9NVD4|uniprotkb:B2RE98|ensembl:ENSP00000210444.5	psi-mi:o84623_chltr(display_long)|uniprotkb:CT_618(locus name)	psi-mi:sias_human(display_long)|uniprotkb:N-acetylneuraminic acid phosphate synthase(gene name synonym)|uniprotkb:NANS(gene name)|psi-mi:NANS(display_short)|uniprotkb:SAS(gene name synonym)|uniprotkb:3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase(gene name synonym)|uniprotkb:Sialic acid phosphate synthase(gene name synonym)|uniprotkb:Sialic acid synthase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303627|imex:IM-27647-13	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220135.1|refseq:WP_010725275.1|mint:O84623"	"efo:""Orphanet:168454""|ensembl:ENSG00000095380.11(gene)|ensembl:ENST00000210444.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006055""(CMP-N-acetylneuraminate biosynthetic process)|go:""GO:0016051""(carbohydrate biosynthetic process)|go:""GO:0046380""(N-acetylneuraminate biosynthetic process)|go:""GO:0047444""(N-acylneuraminate-9-phosphate synthase activity)|go:""GO:0050462""(N-acetylneuraminate synthase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070085""(glycosylation)|interpro:IPR006013(Antifreeze, type III)|interpro:IPR006190(Antifreeze-like/N-acetylneuraminic acid synthase C-terminal)|interpro:IPR013132(N-acetylneuraminic acid synthase, N-terminal)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR013974(SAF domain)|interpro:IPR036732|interpro:IPR051690|mint:Q9NR45|rcsb pdb:1WVO|reactome:R-HSA-4085001|refseq:NP_061819.2|panther:PTHR42966(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:jrgFj+3qHniid9gbFfQSpN1v0yg272561	rogid:kdMBtQ/FC9c+6Bi79j1RkkifZ2k9606	intact-crc:E92308F4E39F0E42|rigid:4oHZMztWCXrp5wCWqQl3f/cyX6g	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84733	uniprotkb:Q96AA3	intact:EBI-22303635	intact:EBI-6269616|uniprotkb:Q96J03|ensembl:ENSP00000296292.3	psi-mi:o84733_chltr(display_long)|uniprotkb:CT_728(locus name)	psi-mi:rft1_human(display_long)|uniprotkb:Protein RFT1 homolog(gene name synonym)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303646|imex:IM-27647-51	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005384""(manganese ion transmembrane transporter activity)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0030026""(intracellular manganese ion homeostasis)|refseq:NP_220247.1|refseq:WP_009872105.1|interpro:IPR008217(Protein of unknown function DUF125, transmembrane)|mint:O84733"	"ensembl:ENSG00000163933.11(gene)|ensembl:ENST00000296292.8(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0006488""(dolichol-linked oligosaccharide biosynthetic process)|go:""GO:0034202""(glycolipid floppase activity)|go:""GO:0034203""(glycolipid translocation)|interpro:IPR007594(RFT1)|mint:Q96AA3|reactome:R-HSA-446193|reactome:R-HSA-4570571|refseq:NP_443091.1|efo:""Orphanet:244310""|panther:PTHR13117(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:vLTq1R+bG9wT6RNToV/a6lRGpQ0272561	rogid:off+uN6MYDiLT5q1oh7G2sd6RXw9606	intact-crc:EC070964F4FEF1E2|rigid:KvCgcQYs8exwZmnc59Vw33LiyoQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84733	uniprotkb:O60779	intact:EBI-22303635	intact:EBI-3941998|uniprotkb:Q8WV87|uniprotkb:Q9UBL7|uniprotkb:Q9UN31|uniprotkb:Q9UN43|uniprotkb:B2R9H0|uniprotkb:Q9UKJ2|uniprotkb:B4E1X4|ensembl:ENSP00000236137.5	psi-mi:o84733_chltr(display_long)|uniprotkb:CT_728(locus name)	psi-mi:s19a2_human(display_long)|uniprotkb:SLC19A2(gene name)|psi-mi:SLC19A2(display_short)|uniprotkb:THT1(gene name synonym)|uniprotkb:TRMA(gene name synonym)|uniprotkb:Solute carrier family 19 member 2(gene name synonym)|uniprotkb:Thiamine carrier 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303646|imex:IM-27647-51	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005384""(manganese ion transmembrane transporter activity)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0030026""(intracellular manganese ion homeostasis)|refseq:NP_220247.1|refseq:WP_009872105.1|interpro:IPR008217(Protein of unknown function DUF125, transmembrane)|mint:O84733"	"ensembl:ENSG00000117479.15(gene)|ensembl:ENST00000236137.10(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008517""(folic acid transmembrane transporter activity)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0015234""(thiamine transmembrane transporter activity)|go:""GO:0015888""(thiamine transport)|go:""GO:0016020""(membrane)|go:""GO:0031923""(pyridoxine transport)|go:""GO:0042723""(thiamine-containing compound metabolic process)|go:""GO:0055085""(transmembrane transport)|go:""GO:0071934""(thiamine transmembrane transport)|interpro:IPR002666(Reduced folate carrier)|interpro:IPR028338|interpro:IPR036259|mint:O60779|reactome:R-HSA-196819|refseq:NP_001306596.1|refseq:NP_008927.1|efo:""Orphanet:49827""|panther:PTHR10686(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:vLTq1R+bG9wT6RNToV/a6lRGpQ0272561	rogid:jaxPhDzyD6VTkLBvxtw/nCixzAE9606	intact-crc:EC070964F4FEF1E2|rigid:KvCgcQYs8exwZmnc59Vw33LiyoQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84733	uniprotkb:P0CG08	intact:EBI-22303635	intact:EBI-11905631|uniprotkb:A6NKF9|uniprotkb:A6NN37|uniprotkb:B2RUV3|uniprotkb:B3KMN3|uniprotkb:Q53FQ9|uniprotkb:Q5T2V8|uniprotkb:Q5T5P5|uniprotkb:Q659E2|uniprotkb:Q6NVY5|uniprotkb:Q9P0S4|uniprotkb:Q9Y302|ensembl:ENSP00000358233.4	psi-mi:o84733_chltr(display_long)|uniprotkb:CT_728(locus name)	psi-mi:gphrb_human(display_long)|uniprotkb:GPR89B(gene name)|psi-mi:GPR89B(display_short)|uniprotkb:GPR89C(gene name synonym)|uniprotkb:Protein GPR89B(gene name synonym)|uniprotkb:GPHR(gene name synonym)|uniprotkb:GPR89(gene name synonym)|uniprotkb:SH120(gene name synonym)|uniprotkb:HSPC201(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303646|imex:IM-27647-51	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005384""(manganese ion transmembrane transporter activity)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0030026""(intracellular manganese ion homeostasis)|refseq:NP_220247.1|refseq:WP_009872105.1|interpro:IPR008217(Protein of unknown function DUF125, transmembrane)|mint:O84733"	"refseq:NP_001091081.1|refseq:NP_057418.1|refseq:XP_005277458.1|refseq:XP_006711555.1|refseq:XP_011507915.1|refseq:XP_011508212.1|ensembl:ENSG00000188092.15(gene)|ensembl:ENST00000314163.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0008308""(voltage-gated monoatomic anion channel activity)|go:""GO:0015031""(protein transport)|go:""GO:0030217""(T cell differentiation)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0034702""(monoatomic ion channel complex)|go:""GO:0051452""(intracellular pH reduction)|interpro:IPR015672(G-protein coupled receptor 89-related)|interpro:IPR022535|interpro:IPR025969|mint:P0CG08|panther:PTHR15948(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:vLTq1R+bG9wT6RNToV/a6lRGpQ0272561	rogid:4pAq3FBvosP3U/y/iw/ixx+QPcM9606	intact-crc:EC070964F4FEF1E2|rigid:KvCgcQYs8exwZmnc59Vw33LiyoQ	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84819	uniprotkb:P52701	intact:EBI-22303654	intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9|ensembl:ENSP00000234420.5	psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name)	psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303686|imex:IM-27647-71	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220333.1|refseq:WP_010725353.1|mint:O84819"	"panther:PTHR11361(orthology-group)|ensembl:ENSG00000116062.19(gene)|ensembl:ENST00000234420.11(transcript)|go:""GO:0000710""(meiotic mismatch repair)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006298""(mismatch repair)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009411""(response to UV)|go:""GO:0016446""(somatic hypermutation of immunoglobulin genes)|go:""GO:0016447""(somatic recombination of immunoglobulin gene segments)|go:""GO:0019899""(enzyme binding)|go:""GO:0030983""(mismatched DNA binding)|go:""GO:0032137""(guanine/thymine mispair binding)|go:""GO:0032301""(MutSalpha complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045190""(isotype switching)|go:""GO:0045910""(negative regulation of DNA recombination)|go:""GO:0051096""(positive regulation of helicase activity)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|interpro:IPR045076|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|rcsb pdb:8AG6|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|refseq:NP_000170.1|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|efo:""Orphanet:144""|efo:""Orphanet:252202""|dip:DIP-32972N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561	rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606	intact-crc:25A9612365B720FD|rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84819	uniprotkb:O00267	intact:EBI-22303654	intact:EBI-710464|ensembl:ENSP00000404029.4|ensembl:ENSP00000469090.1|ensembl:ENSP00000470252.1|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639	psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name)	psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303686|imex:IM-27647-71	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220333.1|refseq:WP_010725353.1|mint:O84819"	"ensembl:ENSG00000196235.14(gene)|ensembl:ENST00000432763.7(transcript)|ensembl:ENST00000598725.5(transcript)|ensembl:ENST00000599117.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0019899""(enzyme binding)|go:""GO:0032044""(DSIF complex)|go:""GO:0032785""(negative regulation of DNA-templated transcription, elongation)|go:""GO:0032786""(positive regulation of DNA-templated transcription, elongation)|go:""GO:0034243""(regulation of transcription elongation by RNA polymerase II)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0140673""(transcription elongation-coupled chromatin remodeling)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|rcsb pdb:7OKX|rcsb pdb:7OKY|rcsb pdb:7OL0|rcsb pdb:7PKS|rcsb pdb:7UNC|rcsb pdb:7UND|rcsb pdb:7YCX|rcsb pdb:8A3Y|rcsb pdb:8P4C|rcsb pdb:8P4D|rcsb pdb:8P4E|rcsb pdb:8P4F|rcsb pdb:8RBX|rcsb pdb:8UHA|rcsb pdb:8UHD|rcsb pdb:8UHG|rcsb pdb:8UI0|rcsb pdb:8UIS|rcsb pdb:8W8E|rcsb pdb:8W8F|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N|panther:PTHR11125(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561	rogid:8VodOhZyrmNy3xxDTTsB8KugN849606	intact-crc:25A9612365B720FD|rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84819	uniprotkb:Q8TF05	intact:EBI-22303654	intact:EBI-1056262|uniprotkb:Q99774|uniprotkb:Q9UNQ7|ensembl:ENSP00000383402.3	psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name)	psi-mi:pp4r1_human(display_long)|uniprotkb:PPP4R1(gene name)|psi-mi:PPP4R1(display_short)|uniprotkb:MEG1(gene name synonym)|uniprotkb:PP4R1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303686|imex:IM-27647-71	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220333.1|refseq:WP_010725353.1|mint:O84819"	"refseq:NP_001035847.1|refseq:NP_005125.1|ensembl:ENSG00000154845.16(gene)|ensembl:ENST00000400556.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0030289""(protein phosphatase 4 complex)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033461|interpro:IPR051023|mint:Q8TF05|panther:PTHR10648(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561	rogid:c7WdQEzkeS6LDpC2GD9czxBdWj09606	intact-crc:25A9612365B720FD|rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84819	uniprotkb:P43246	intact:EBI-22303654	intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146.2	psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name)	psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303686|imex:IM-27647-71	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220333.1|refseq:WP_010725353.1|mint:O84819"	"efo:""Orphanet:144""|efo:""Orphanet:252202""|ensembl:ENSG00000095002.16(gene)|ensembl:ENST00000233146.7(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0002204""(somatic recombination of immunoglobulin genes involved in immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006281""(DNA repair)|go:""GO:0006298""(mismatch repair)|go:""GO:0006301""(postreplication repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006312""(mitotic recombination)|go:""GO:0007281""(germ cell development)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008584""(male gonad development)|go:""GO:0010165""(response to X-ray)|go:""GO:0010224""(response to UV-B)|go:""GO:0016020""(membrane)|go:""GO:0016446""(somatic hypermutation of immunoglobulin genes)|go:""GO:0016447""(somatic recombination of immunoglobulin gene segments)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019237""(centromeric DNA binding)|go:""GO:0019724""(B cell mediated immunity)|go:""GO:0030183""(B cell differentiation)|go:""GO:0031573""(mitotic intra-S DNA damage checkpoint signaling)|go:""GO:0032137""(guanine/thymine mispair binding)|go:""GO:0032301""(MutSalpha complex)|go:""GO:0032302""(MutSbeta complex)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043570""(maintenance of DNA repeat elements)|go:""GO:0045190""(isotype switching)|go:""GO:0045910""(negative regulation of DNA recombination)|go:""GO:0048298""(positive regulation of isotype switching to IgA isotypes)|go:""GO:0048304""(positive regulation of isotype switching to IgG isotypes)|go:""GO:0051096""(positive regulation of helicase activity)|go:""GO:0071168""(protein localization to chromatin)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|interpro:IPR045076|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|rcsb pdb:8AG6|rcsb pdb:8OLX|rcsb pdb:8OM5|rcsb pdb:8OM9|rcsb pdb:8OMA|rcsb pdb:8OMO|rcsb pdb:8OMQ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|refseq:NP_000242.1|refseq:NP_001245210.1|dip:DIP-35054N|panther:PTHR11361(orthology-group)|ensembl:ENSP00000233146.2|ensembl:ENST00000543555.6|ensembl:ENSP00000442697.1"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561	rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606	intact-crc:25A9612365B720FD|rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84819	uniprotkb:Q96J02	intact:EBI-22303654	intact:EBI-1564678|uniprotkb:O43584|uniprotkb:Q5TEL0|uniprotkb:Q96F66|uniprotkb:Q9BY75|uniprotkb:Q9H451|uniprotkb:Q9H4U5|uniprotkb:A6NEW4|uniprotkb:Q5QP37|uniprotkb:E1P5P3|uniprotkb:B4E234|uniprotkb:F5H217|ensembl:ENSP00000262650.5|ensembl:ENSP00000499786.1	psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name)	psi-mi:itch_human(display_long)|uniprotkb:HECT-type E3 ubiquitin transferase Itchy homolog(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 4(gene name synonym)|uniprotkb:NFE2-associated polypeptide 1(gene name synonym)|uniprotkb:ITCH(gene name)|psi-mi:ITCH(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303686|imex:IM-27647-71	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220333.1|refseq:WP_010725353.1|mint:O84819"	"efo:""Orphanet:228426""|panther:PTHR11254(orthology-group)|dip:DIP-29849N|ensembl:ENSG00000078747.17(gene)|ensembl:ENST00000262650.11(transcript)|ensembl:ENST00000665346.1(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002669""(positive regulation of T cell anergy)|go:""GO:0002870""(T cell anergy)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016874""(ligase activity)|go:""GO:0019787""(ubiquitin-like protein transferase activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034450""(ubiquitin-ubiquitin ligase activity)|go:""GO:0035519""(protein K29-linked ubiquitination)|go:""GO:0035739""(CD4-positive, alpha-beta T cell proliferation)|go:""GO:0035872""(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:""GO:0039532""(negative regulation of cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045236""(CXCR chemokine receptor binding)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050687""(negative regulation of defense response to virus)|go:""GO:0051607""(defense response to virus)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0060544""(regulation of necroptotic process)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0090085""(regulation of protein deubiquitination)|go:""GO:0141198""(protein branched polyubiquitination)|go:""GO:1902036""(regulation of hematopoietic stem cell differentiation)|go:""GO:1990763""(arrestin family protein binding)|go:""GO:2000562""(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|interpro:IPR050409|mint:Q96J02|rcsb pdb:2DMV|rcsb pdb:2KYK|rcsb pdb:2NQ3|rcsb pdb:2P4R|rcsb pdb:2YSF|rcsb pdb:3TUG|rcsb pdb:4ROF|rcsb pdb:5C7M|rcsb pdb:5CQ2|rcsb pdb:5DWS|rcsb pdb:5DZD|rcsb pdb:5SXP|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-2122948|reactome:R-HSA-5610780|reactome:R-HSA-5632684|reactome:R-HSA-5675482|reactome:R-HSA-8939236|reactome:R-HSA-936440|reactome:R-HSA-9692916|reactome:R-HSA-983168|refseq:NP_001244066.1|refseq:NP_001244067.1|refseq:NP_001311126.1|refseq:NP_001311127.1|refseq:NP_113671.3|refseq:XP_016883578.1|refseq:XP_016883580.1"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561	rogid:JyySOfI+ZHOI1mvdxWDGN6njgCY9606	intact-crc:25A9612365B720FD|rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84819	uniprotkb:Q8N3F8	intact:EBI-22303654	intact:EBI-1056885|uniprotkb:Q5TI16|uniprotkb:Q7RTP5|uniprotkb:Q8N3N8|uniprotkb:Q9BVL9|uniprotkb:Q9BY92|uniprotkb:Q9UH43|uniprotkb:Q9UH44|uniprotkb:Q9UH45|ensembl:ENSP00000215957.6	psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name)	psi-mi:milk1_human(display_long)|uniprotkb:MICALL1(gene name)|psi-mi:MICALL1(display_short)|uniprotkb:KIAA1668(gene name synonym)|uniprotkb:MIRAB13(gene name synonym)|uniprotkb:Molecule interacting with Rab13(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303686|imex:IM-27647-71	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220333.1|refseq:WP_010725353.1|mint:O84819"	"refseq:NP_203744.1|ensembl:ENSG00000100139.14(gene)|ensembl:ENST00000215957.10(transcript)|go:""GO:0005770""(late endosome)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0010009""(cytoplasmic side of endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032458""(slow endocytic recycling)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:0097320""(plasma membrane tubulation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR022735|interpro:IPR036872|interpro:IPR050540|mint:Q8N3F8|rcsb pdb:2KSP"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561	rogid:G64P9EtjEfLIVLYkb+w3vCWaT0w9606	intact-crc:25A9612365B720FD|rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84819	uniprotkb:Q6L8Q7	intact:EBI-22303654	intact:EBI-2515865|uniprotkb:Q8IYU3|uniprotkb:Q8NDU2|uniprotkb:Q8TE78|uniprotkb:B4DTU8|ensembl:ENSP00000309142.7	psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name)	psi-mi:pde12_human(display_long)|uniprotkb:PDE12(gene name)|psi-mi:PDE12(display_short)|uniprotkb:Mitochondrial deadenylase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303686|imex:IM-27647-71	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220333.1|refseq:WP_010725353.1|mint:O84819"	"refseq:NP_808881.3|ensembl:ENSG00000174840.10(gene)|ensembl:ENST00000311180.9(transcript)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000288""(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:0000958""(mitochondrial mRNA catabolic process)|go:""GO:0004527""(exonuclease activity)|go:""GO:0004535""(""poly(A)-specific ribonuclease activity"")|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0034611""(oligoribonucleotidase activity)|go:""GO:0035457""(cellular response to interferon-alpha)|go:""GO:0044528""(regulation of mitochondrial mRNA stability)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090304""(nucleic acid metabolic process)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|interpro:IPR048821|interpro:IPR050410|mint:Q6L8Q7|rcsb pdb:4Z0V|rcsb pdb:4Z2B|rcsb pdb:4ZKF|reactome:R-HSA-8983711|panther:PTHR12121(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561	rogid:P2ALFhSP4Qnqnd08vmkOcVoXe/I9606	intact-crc:25A9612365B720FD|rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84819	uniprotkb:Q9Y6V7	intact:EBI-22303654	intact:EBI-719274|uniprotkb:Q53FJ1|ensembl:ENSP00000247003.3|uniprotkb:E7ENA0|uniprotkb:Q9BVQ8	psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name)	psi-mi:ddx49_human(display_long)|uniprotkb:DEAD box protein 49(gene name synonym)|uniprotkb:DDX49(gene name)|psi-mi:DDX49(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303686|imex:IM-27647-71	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220333.1|refseq:WP_010725353.1|mint:O84819"	"refseq:NP_061943.2|ensembl:ENSG00000105671.12(gene)|ensembl:ENST00000247003.9(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006364""(rRNA processing)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0044357""(regulation of rRNA stability)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR050079|mint:Q9Y6V7|reactome:R-HSA-6790901|reactome:R-HSA-6791226|panther:PTHR24031(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561	rogid:Yfej1zXpPTue3eewQcR5OpNILeM9606	intact-crc:25A9612365B720FD|rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84819	uniprotkb:P60510	intact:EBI-22303654	intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387.7|ensembl:ENSP00000455995.1	psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name)	psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303686|imex:IM-27647-71	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220333.1|refseq:WP_010725353.1|mint:O84819"	"refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923.14(gene)|ensembl:ENST00000279387.12(transcript)|ensembl:ENST00000561610.1(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000785""(chromatin)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0010569""(regulation of double-strand break repair via homologous recombination)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0030289""(protein phosphatase 4 complex)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|go:""GO:2000779""(regulation of double-strand break repair)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186(""Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase"")|interpro:IPR029052|interpro:IPR047129|mint:P60510|reactome:R-HSA-5693607|panther:PTHR45619(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561	rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606	intact-crc:25A9612365B720FD|rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84819	uniprotkb:Q9NYJ1	intact:EBI-22303654	intact:EBI-22303661|ensembl:ENSP00000347919.4|ensembl:ENSP00000437772.1|ensembl:ENSP00000443795.1|uniprotkb:B2RAA0|uniprotkb:Q69YU4	psi-mi:o84819_chltr(display_long)|uniprotkb:CT_813(locus name)	psi-mi:coa4_human(display_long)|uniprotkb:COA4(gene name)|psi-mi:COA4(display_short)|uniprotkb:CHCHD8(gene name synonym)|uniprotkb:E2IG2(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 8(gene name synonym)|uniprotkb:E2-induced gene 2 protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303686|imex:IM-27647-71	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220333.1|refseq:WP_010725353.1|mint:O84819"	"ensembl:ENSG00000181924.8(gene)|ensembl:ENST00000355693.5(transcript)|ensembl:ENST00000537289.2(transcript)|ensembl:ENST00000545127.1(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0033617""(mitochondrial cytochrome c oxidase assembly)|interpro:IPR010625(CHCH)|interpro:IPR039870|mint:Q9NYJ1|reactome:R-HSA-1268020|panther:PTHR13639(orthology-group)|refseq:NP_057649.2|refseq:XP_016873372.1|refseq:XP_016873373.1"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:h+iT8ll8HZRbGJFygUbuA0mwjoE272561	rogid:L1PGDFR+DvWHCwqfW6bL3atHvVs9606	intact-crc:25A9612365B720FD|rigid:LLfbFXeEQ2gBj+ErBRHlMhfTbYE	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84820	uniprotkb:Q9Y4B6	intact:EBI-22303701	intact:EBI-1996353|uniprotkb:Q2YD74|uniprotkb:Q8TBD9|uniprotkb:Q9HCA1|uniprotkb:Q9UG37|ensembl:ENSP00000393183.2|ensembl:ENSP00000506880.1|intact:EBI-2559078|intact:EBI-28988191	psi-mi:o84820_chltr(display_long)|uniprotkb:CT_814(locus name)	psi-mi:dcaf1_human(display_long)|uniprotkb:DCAF1(gene name)|psi-mi:DCAF1(display_short)|uniprotkb:HIV-1 Vpr-binding protein(gene name synonym)|uniprotkb:KIAA0800(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:VPRBP(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303708|imex:IM-27647-31	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220334.1|refseq:WP_010725354.1|mint:O84820"	"go:""GO:1990244""(histone H2AT120 kinase activity)|refseq:NP_001165375.1|refseq:NP_055518.1|refseq:XP_011532575.1|refseq:XP_011532576.1|refseq:XP_011532577.1|refseq:XP_011532578.1|refseq:XP_011532579.1|ensembl:ENSG00000145041.17(gene)|ensembl:ENST00000423656.5(transcript)|ensembl:ENST00000684031.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0033151""(""V(D)J recombination"")|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035212""(cell competition in a multicellular organism)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|rcsb pdb:4P7I|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|mint:Q9Y4B6|rcsb pdb:3WA0|rcsb pdb:4CC9|rcsb pdb:4PXW|rcsb pdb:4Z8L|rcsb pdb:5AJA|rcsb pdb:5JK7|rcsb pdb:6N45|rcsb pdb:6ZUE|rcsb pdb:6ZX9|rcsb pdb:7OKQ|rcsb pdb:7SSE|rcsb pdb:7UFV|rcsb pdb:7V7B|rcsb pdb:7V7C|rcsb pdb:8F8E|rcsb pdb:8OG5|rcsb pdb:8OG6|rcsb pdb:8OG7|rcsb pdb:8OG8|rcsb pdb:8OG9|rcsb pdb:8OGA|rcsb pdb:8OGB|rcsb pdb:8OGC|rcsb pdb:8OO5|rcsb pdb:8OOD|rcsb pdb:9BHR|rcsb pdb:9BHS|rcsb pdb:9C1Q|reactome:R-HSA-983168|refseq:XP_005276810.1|refseq:XP_005276812.1|panther:PTHR13129(orthology-group)|refseq:XP_016863035.1|refseq:XP_016863036.1|refseq:XP_016863037.1|refseq:XP_016863038.1|refseq:XP_016863039.1|dip:DIP-47048N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:vK/WLNMoij0Z894SiWg1VaF2vHU272561	rogid:qs3qG0MM135EE/DjC1S/gCLRFhc9606	intact-crc:F16C38B707E4A122|rigid:hVcEJUy4gtL1DEOT/9gHN0b6zkY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84820	uniprotkb:O43164	intact:EBI-22303701	intact:EBI-1996038|uniprotkb:D3DSZ5|ensembl:ENSP00000354775.2|ensembl:ENSP00000355284.3|uniprotkb:Q68D49|uniprotkb:Q8N1G5|uniprotkb:A8K6U4	psi-mi:o84820_chltr(display_long)|uniprotkb:CT_814(locus name)	psi-mi:pja2_human(display_long)|uniprotkb:PJA2(gene name)|psi-mi:PJA2(display_short)|uniprotkb:KIAA0438(gene name synonym)|uniprotkb:RNF131(gene name synonym)|uniprotkb:RING finger protein 131(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Praja-2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303708|imex:IM-27647-31	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220334.1|refseq:WP_010725354.1|mint:O84820"	"ensembl:ENSG00000198961.10(gene)|ensembl:ENST00000361189.7(transcript)|ensembl:ENST00000361557.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0007616""(long-term memory)|go:""GO:0010738""(regulation of protein kinase A signaling)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0034137""(positive regulation of toll-like receptor 2 signaling pathway)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900745""(positive regulation of p38MAPK cascade)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O43164|reactome:R-HSA-983168|refseq:NP_055634.3|panther:PTHR15710(orthology-group)|refseq:XP_016865588.1|dip:DIP-47040N"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:vK/WLNMoij0Z894SiWg1VaF2vHU272561	rogid:z0OkXLozXymqwyF+xQR+PFa+bQI9606	intact-crc:F16C38B707E4A122|rigid:hVcEJUy4gtL1DEOT/9gHN0b6zkY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84820	uniprotkb:Q9BW61	intact:EBI-22303701	intact:EBI-2510241|ensembl:ENSP00000352928.3|ensembl:ENSP00000472171.1|ensembl:ENSP00000473086.1	psi-mi:o84820_chltr(display_long)|uniprotkb:CT_814(locus name)	psi-mi:dda1_human(display_long)|uniprotkb:DDA1(gene name)|psi-mi:DDA1(display_short)|uniprotkb:C19orf58(gene name synonym)|uniprotkb:PCIA1(gene name synonym)|uniprotkb:Placenta cross-immune reaction antigen 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303708|imex:IM-27647-31	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220334.1|refseq:WP_010725354.1|mint:O84820"	"refseq:NP_076955.1|dip:DIP-53527N|ensembl:ENSG00000130311.11(gene)|ensembl:ENST00000359866.9(transcript)|ensembl:ENST00000593466.5(transcript)|ensembl:ENST00000596582.1(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0005654""(nucleoplasm)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR018276|interpro:IPR033575|mint:Q9BW61|rcsb pdb:6DSZ|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:8G46|rcsb pdb:8QH5|rcsb pdb:8ROX|rcsb pdb:8ROY|rcsb pdb:8TL6|reactome:R-HSA-8951664|panther:PTHR31879(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:vK/WLNMoij0Z894SiWg1VaF2vHU272561	rogid:yD3tRVKVhirdHUj58DCTphW7ZYs9606	intact-crc:F16C38B707E4A122|rigid:hVcEJUy4gtL1DEOT/9gHN0b6zkY	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84826	uniprotkb:Q5TEU4	intact:EBI-22303716	intact:EBI-10762958|uniprotkb:A8K166|uniprotkb:Q6GPH3|uniprotkb:Q9H6F4|ensembl:ENSP00000367346.5	psi-mi:y819_chltr(display_long)|uniprotkb:CT_819(locus name)	psi-mi:nduf5_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5(gene name synonym)|uniprotkb:Putative methyltransferase NDUFAF5(gene name synonym)|uniprotkb:NDUFAF5(gene name)|psi-mi:NDUFAF5(display_short)|uniprotkb:C20orf7(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303725|imex:IM-27647-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0030162""(regulation of proteolysis)|panther:PTHR23291(orthology-group)|refseq:NP_220340.1|refseq:WP_009872956.1|interpro:IPR006214(Protein of unknown function UPF0005)|mint:O84826"	"efo:""Orphanet:2609""|ensembl:ENSG00000101247.18(gene)|ensembl:ENST00000378106.10(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0008757""(S-adenosylmethionine-dependent methyltransferase activity)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0030961""(peptidyl-arginine hydroxylation)|go:""GO:0032259""(methylation)|go:""GO:0032981""(mitochondrial respiratory chain complex I assembly)|go:""GO:0099617""(matrix side of mitochondrial inner membrane)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|interpro:IPR050602|mint:Q5TEU4|reactome:R-HSA-6799198|refseq:NP_001034464.1|refseq:NP_077025.2|panther:PTHR13090(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:ICKqu0SV5jIHm0iWAZG30pvCx3k272561	rogid:BC4jrAunVf7T4Cbrr/sZVFnkrfA9606	intact-crc:19FF8BDAA3E7A079|rigid:jeZ8eM+fiRf+8PpUMbyM7zfk0gg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84826	uniprotkb:Q8N5G0	intact:EBI-22303716	intact:EBI-6570855|uniprotkb:C9JYT8|uniprotkb:Q9BRT5|ensembl:ENSP00000427407.2	psi-mi:y819_chltr(display_long)|uniprotkb:CT_819(locus name)	psi-mi:sim20_human(display_long)|uniprotkb:SMIM20(gene name)|psi-mi:SMIM20(display_short)|uniprotkb:C4orf52(gene name synonym)|uniprotkb:MITRAC7(gene name synonym)|uniprotkb:Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303725|imex:IM-27647-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0030162""(regulation of proteolysis)|panther:PTHR23291(orthology-group)|refseq:NP_220340.1|refseq:WP_009872956.1|interpro:IPR006214(Protein of unknown function UPF0005)|mint:O84826"	"refseq:NP_001138904.1|ensembl:ENSG00000250317.9(gene)|ensembl:ENST00000506197.3(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0033617""(mitochondrial cytochrome c oxidase assembly)|interpro:IPR027917|mint:Q8N5G0|reactome:R-HSA-9864848|panther:PTHR34923(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:ICKqu0SV5jIHm0iWAZG30pvCx3k272561	rogid:yqRjpvlmOpU7RfsXACpQ7ytSFZE9606	intact-crc:19FF8BDAA3E7A079|rigid:jeZ8eM+fiRf+8PpUMbyM7zfk0gg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84826	uniprotkb:A1L188	intact:EBI-22303716	intact:EBI-20593474|ensembl:ENSP00000400184.2	psi-mi:y819_chltr(display_long)|uniprotkb:CT_819(locus name)	psi-mi:nduf8_human(display_long)|uniprotkb:NDUFAF8(gene name)|psi-mi:NDUFAF8(display_short)|uniprotkb:C17orf89(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303725|imex:IM-27647-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0030162""(regulation of proteolysis)|panther:PTHR23291(orthology-group)|refseq:NP_220340.1|refseq:WP_009872956.1|interpro:IPR006214(Protein of unknown function UPF0005)|mint:O84826"	"ensembl:ENSG00000224877.4(gene)|ensembl:ENST00000431388.3(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0032981""(mitochondrial respiratory chain complex I assembly)|interpro:IPR034595|mint:A1L188|reactome:R-HSA-6799198|refseq:NP_001079990.1|panther:PTHR34561(orthology-group)|efo:""Orphanet:2609"""	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:ICKqu0SV5jIHm0iWAZG30pvCx3k272561	rogid:S/mahr2flAFENqydZrw3d9WyQqM9606	intact-crc:19FF8BDAA3E7A079|rigid:jeZ8eM+fiRf+8PpUMbyM7zfk0gg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84826	uniprotkb:O15067	intact:EBI-22303716	intact:EBI-1052653|uniprotkb:A6H8V8|ensembl:ENSP00000313490.6	psi-mi:y819_chltr(display_long)|uniprotkb:CT_819(locus name)	psi-mi:pur4_human(display_long)|uniprotkb:Phosphoribosylformylglycineamide amidotransferase(gene name synonym)|uniprotkb:Formylglycinamide ribotide amidotransferase(gene name synonym)|uniprotkb:PFAS(gene name)|psi-mi:PFAS(display_short)|uniprotkb:KIAA0361(gene name synonym)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303725|imex:IM-27647-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0030162""(regulation of proteolysis)|panther:PTHR23291(orthology-group)|refseq:NP_220340.1|refseq:WP_009872956.1|interpro:IPR006214(Protein of unknown function UPF0005)|mint:O84826"	"refseq:NP_036525.1|ensembl:ENSG00000178921.14(gene)|ensembl:ENST00000314666.11(transcript)|go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006177""(GMP biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0009168""(purine ribonucleoside monophosphate biosynthetic process)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0044208""('de novo' AMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097065""(anterior head development)|go:""GO:0097294""('de novo' XMP biosynthetic process)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR029062|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR040707|interpro:IPR041609|interpro:IPR055181|mint:O15067|reactome:R-HSA-73817|panther:PTHR10099(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:ICKqu0SV5jIHm0iWAZG30pvCx3k272561	rogid:e52AyHjHUrLjnoJP+rInkcvfGJk9606	intact-crc:19FF8BDAA3E7A079|rigid:jeZ8eM+fiRf+8PpUMbyM7zfk0gg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84826	uniprotkb:Q13505	intact:EBI-22303716	intact:EBI-1052588|uniprotkb:B1AVR9|uniprotkb:B1AVS0|uniprotkb:B2R9P4|uniprotkb:Q9BUU3|uniprotkb:A0A0A0MRK6|ensembl:ENSP00000357360.3	psi-mi:y819_chltr(display_long)|uniprotkb:CT_819(locus name)	psi-mi:mtx1_human(display_long)|uniprotkb:MTX1(gene name)|psi-mi:MTX1(display_short)|uniprotkb:MTX(gene name synonym)|uniprotkb:MTXN(gene name synonym)|uniprotkb:Mitochondrial outer membrane import complex protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303725|imex:IM-27647-15	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0030162""(regulation of proteolysis)|panther:PTHR23291(orthology-group)|refseq:NP_220340.1|refseq:WP_009872956.1|interpro:IPR006214(Protein of unknown function UPF0005)|mint:O84826"	"refseq:NP_002446.3|refseq:NP_942584.2|ensembl:ENSG00000173171.15(gene)|ensembl:ENST00000368376.8(transcript)|go:""GO:0001401""(SAM complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007007""(inner mitochondrial membrane organization)|go:""GO:0007595""(lactation)|go:""GO:0016020""(membrane)|mint:Q13505|go:""GO:0045040""(protein insertion into mitochondrial outer membrane)|go:""GO:0140275""(MIB complex)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|interpro:IPR050931|reactome:R-HSA-1268020|reactome:R-HSA-8949613|reactome:R-HSA-9013404|panther:PTHR12289(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:ICKqu0SV5jIHm0iWAZG30pvCx3k272561	rogid:LoRdRoXuGOFmrPBEt324uUHgKos9606	intact-crc:19FF8BDAA3E7A079|rigid:jeZ8eM+fiRf+8PpUMbyM7zfk0gg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84853	uniprotkb:Q8WVP7	intact:EBI-22303735	intact:EBI-6138627|uniprotkb:A4D242|uniprotkb:Q8N3E3|uniprotkb:Q96QZ5|uniprotkb:Q9H5N0|uniprotkb:Q9HAG9|uniprotkb:Q9UDN5|uniprotkb:Q9Y6U2|ensembl:ENSP00000326604.7	psi-mi:o84853_chltr(display_long)|uniprotkb:CT_846(locus name)	psi-mi:lmbr1_human(display_long)|uniprotkb:LMBR1(gene name)|psi-mi:LMBR1(display_short)|uniprotkb:C7orf2(gene name synonym)|uniprotkb:DIF14(gene name synonym)|uniprotkb:Differentiation-related gene 14 protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303742|imex:IM-27647-101	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220367.1|refseq:WP_009872233.1|mint:O84853"	"ensembl:ENSG00000105983.23(gene)|ensembl:ENST00000353442.10(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0042733""(embryonic digit morphogenesis)|interpro:IPR006876(LMBR1-like conserved region)|interpro:IPR008075(Lipocalin-1 receptor)|mint:Q8WVP7|refseq:NP_071903.2|refseq:XP_016867996.1|efo:""Orphanet:2378""|efo:""Orphanet:931""|efo:""Orphanet:93321""|efo:""Orphanet:93336""|efo:""Orphanet:93405""|efo:""Orphanet:988""|panther:PTHR12625(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:E5HBJR0LBremFNwkwQd/1CHiNnc272561	rogid:a5rq7+LN7TI2Niu8fC9MeRARQvU9606	intact-crc:D86AD9FF8ECD6058|rigid:iege/AERe27gbA4lIWnfcRrNjD0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84853	uniprotkb:O76024	intact:EBI-22303735	intact:EBI-720609|uniprotkb:Q8N6I3|uniprotkb:Q9UNW6|uniprotkb:B2R797|uniprotkb:D3DVT1|ensembl:ENSP00000226760.1|ensembl:ENSP00000423337.1|ensembl:ENSP00000506978.1	psi-mi:o84853_chltr(display_long)|uniprotkb:CT_846(locus name)	psi-mi:wfs1_human(display_long)|uniprotkb:WFS1(gene name)|psi-mi:WFS1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303742|imex:IM-27647-101	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220367.1|refseq:WP_009872233.1|mint:O84853"	"efo:""Orphanet:3463""|efo:""Orphanet:411590""|efo:""Orphanet:90635""|efo:""Orphanet:98991""|ensembl:ENSG00000109501.15(gene)|ensembl:ENST00000226760.5(transcript)|ensembl:ENST00000503569.5(transcript)|ensembl:ENST00000684087.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001822""(kidney development)|go:""GO:0003091""(renal water homeostasis)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006983""(ER overload response)|go:""GO:0007601""(visual perception)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0022417""(obsolete protein maturation by protein folding)|go:""GO:0030141""(secretory granule)|go:""GO:0030425""(dendrite)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031016""(pancreas development)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042048""(olfactory behavior)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045927""(positive regulation of growth)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0050877""(nervous system process)|go:""GO:0051117""(ATPase binding)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0070628""(proteasome binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903573""(negative regulation of response to endoplasmic reticulum stress)|go:""GO:1903892""(negative regulation of ATF6-mediated unfolded protein response)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000675""(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR026208|interpro:IPR026209|interpro:IPR045400|interpro:IPR045458|interpro:IPR045460|interpro:IPR045461|mint:O76024|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001139325.1|refseq:NP_005996.2|panther:PTHR13098(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:E5HBJR0LBremFNwkwQd/1CHiNnc272561	rogid:bt4NKJUKyrQeJ8emdvrT3sg0Rf49606	intact-crc:D86AD9FF8ECD6058|rigid:iege/AERe27gbA4lIWnfcRrNjD0	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0CI27	uniprotkb:Q5SW79	intact:EBI-22303749|uniprotkb:O84121|uniprotkb:Q99Q56|uniprotkb:Q9AM94|uniprotkb:Q9AMA7|uniprotkb:Q9AMA8|uniprotkb:Q9AMA9|uniprotkb:Q9AMB0|uniprotkb:Q9AMB1|uniprotkb:Q9F7K9|uniprotkb:Q9RFX7	intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500.1|ensembl:ENSP00000483344.1	psi-mi:inca_chltr(display_long)|uniprotkb:incA(gene name)|psi-mi:incA(display_short)|uniprotkb:CT_119(locus name)	psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303771|imex:IM-27647-73	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:6E6A|rcsb pdb:6E7E|refseq:NP_219622.1|refseq:WP_009871466.1|mint:P0CI27"	"refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702.17(gene)|ensembl:ENSG00000276725.4(gene)|ensembl:ENST00000366542.6(transcript)|ensembl:ENST00000612450.4(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0120103""(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029300|interpro:IPR051176|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N|panther:PTHR15715(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:ccmWavz7ZW1HZZFFu1T5BVIQLVs272561	rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606	intact-crc:F88A433BD94005BD|rigid:/Es0wNLUuiX+juWtRxnYT36AFJM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0CI27	uniprotkb:Q08209	intact:EBI-22303749|uniprotkb:O84121|uniprotkb:Q99Q56|uniprotkb:Q9AM94|uniprotkb:Q9AMA7|uniprotkb:Q9AMA8|uniprotkb:Q9AMA9|uniprotkb:Q9AMB0|uniprotkb:Q9AMB1|uniprotkb:Q9F7K9|uniprotkb:Q9RFX7	intact:EBI-352922|uniprotkb:Q8TAW9|uniprotkb:A8K3B7|uniprotkb:B5BUA2|uniprotkb:A1A441|uniprotkb:A8W6Z7|uniprotkb:A8W6Z8|ensembl:ENSP00000378323.3	psi-mi:inca_chltr(display_long)|uniprotkb:incA(gene name)|psi-mi:incA(display_short)|uniprotkb:CT_119(locus name)	psi-mi:pp2ba_human(display_long)|uniprotkb:PPP3CA(gene name)|psi-mi:PPP3CA(display_short)|uniprotkb:CALNA(gene name synonym)|uniprotkb:CNA(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Calcineurin A alpha(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303771|imex:IM-27647-73	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:6E6A|rcsb pdb:6E7E|refseq:NP_219622.1|refseq:WP_009871466.1|mint:P0CI27"	"ensembl:ENSG00000138814.17(gene)|ensembl:ENST00000394854.8(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0001975""(response to amphetamine)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005955""(calcineurin complex)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006816""(calcium ion transport)|go:""GO:0008287""(protein serine/threonine phosphatase complex)|go:""GO:0008544""(epidermis development)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0014883""(transition between fast and slow fiber)|go:""GO:0014898""(cardiac muscle hypertrophy in response to stress)|go:""GO:0016311""(dephosphorylation)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0019897""(extrinsic component of plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0023057""(negative regulation of signaling)|go:""GO:0030018""(Z disc)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0033555""(multicellular organismal response to stress)|go:""GO:0036057""(slit diaphragm)|go:""GO:0042060""(wound healing)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0042383""(sarcolemma)|go:""GO:0043197""(dendritic spine)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045807""(positive regulation of endocytosis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046676""(negative regulation of insulin secretion)|go:""GO:0046878""(positive regulation of saliva secretion)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048741""(skeletal muscle fiber development)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050774""(negative regulation of dendrite morphogenesis)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0051117""(ATPase binding)|go:""GO:0051592""(response to calcium ion)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0061006""(regulation of cell proliferation involved in kidney morphogenesis)|go:""GO:0070262""(peptidyl-serine dephosphorylation)|go:""GO:0070886""(positive regulation of calcineurin-NFAT signaling cascade)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0090193""(positive regulation of glomerulus development)|go:""GO:0097205""(renal filtration)|go:""GO:0097720""(calcineurin-mediated signaling)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099170""(postsynaptic modulation of chemical synaptic transmission)|go:""GO:0110062""(negative regulation of angiotensin-activated signaling pathway)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1903244""(positive regulation of cardiac muscle hypertrophy in response to stress)|go:""GO:1905205""(positive regulation of connective tissue replacement)|go:""GO:1905665""(positive regulation of calcium ion import across plasma membrane)|go:""GO:1905949""(negative regulation of calcium ion import across plasma membrane)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186(""Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase"")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:Q08209|rcsb pdb:1AUI|rcsb pdb:1M63|rcsb pdb:1MF8|rcsb pdb:2JOG|rcsb pdb:2JZI|rcsb pdb:2P6B|rcsb pdb:2R28|rcsb pdb:2W73|rcsb pdb:3LL8|rcsb pdb:4F0Z|rcsb pdb:4Q5U|rcsb pdb:5C1V|rcsb pdb:5SVE|rcsb pdb:6NUC|rcsb pdb:6NUF|rcsb pdb:6NUU|rcsb pdb:6UUQ|rcsb pdb:9B9G|reactome:R-HSA-180024|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763|refseq:NP_000935.1|refseq:NP_001124163.1|refseq:NP_001124164.1|efo:""Orphanet:178469""|efo:""Orphanet:442835""|efo:""Orphanet:565858""|dip:DIP-6095N|panther:PTHR45673(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:ccmWavz7ZW1HZZFFu1T5BVIQLVs272561	rogid:kYtl+Yk39rbcDp5vIjH8WLsZysU9606	intact-crc:F88A433BD94005BD|rigid:/Es0wNLUuiX+juWtRxnYT36AFJM	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q86TI2	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-7475352|uniprotkb:Q8N2J7|uniprotkb:Q1ZZB8|uniprotkb:O75273|uniprotkb:Q8WXD8|uniprotkb:Q9BVR3|uniprotkb:Q6AI37|uniprotkb:Q8N3F5|uniprotkb:Q96NT8|uniprotkb:Q6UAL0|intact:MINT-4535936|uniprotkb:O75868|uniprotkb:Q6ZMT2|uniprotkb:Q6ZNJ5|ensembl:ENSP00000469603.1|ensembl:ENSP00000515514.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:dpp9_human(display_long)|uniprotkb:DPP9(gene name)|psi-mi:DPP9(display_short)|uniprotkb:DPRP2(gene name synonym)|uniprotkb:Dipeptidyl peptidase IV-related protein 2(gene name synonym)|uniprotkb:Dipeptidyl peptidase IX(gene name synonym)|uniprotkb:Dipeptidyl peptidase-like protein 9(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303794|imex:IM-27647-75	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"efo:""Orphanet:2032""|ensembl:ENSG00000142002.19(gene)|ensembl:ENST00000593973.2(transcript)|ensembl:ENST00000598800.5(transcript)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006508""(proteolysis)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008239""(dipeptidyl-peptidase activity)|go:""GO:0031252""(cell leading edge)|go:""GO:0042802""(identical protein binding)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0070269""(pyroptotic inflammatory response)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002469(Peptidase S9B, dipeptidylpeptidase IV N-terminal)|interpro:IPR029058|interpro:IPR045785|interpro:IPR050278|mint:Q86TI2|rcsb pdb:6EOQ|rcsb pdb:6QZV|rcsb pdb:6EOR|rcsb pdb:6X6A|rcsb pdb:6X6C|rcsb pdb:7A3F|rcsb pdb:7JKQ|rcsb pdb:7JN7|rcsb pdb:7SVL|rcsb pdb:7SVN|rcsb pdb:7ZXS|refseq:NP_631898.3|refseq:XP_005259730.1|refseq:XP_011526710.1|refseq:XP_011526712.1|panther:PTHR11731(orthology-group)"	-	-	comment:mint|function:Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:m3rJ6BPsdQqnesPiTY9vclr5hE49606	intact-crc:E6BAADBDB96E0A48|rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc	false	binding-associated region:101-132|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q13596	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303794|imex:IM-27647-75	intact-miscore:0.43	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528.15(gene)|ensembl:ENST00000559844.6(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990460""(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|interpro:IPR036871|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|rcsb pdb:8A1G|rcsb pdb:8ABQ|rcsb pdb:8AFZ|dip:DIP-398N|panther:PTHR10555(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606	intact-crc:E6BAADBDB96E0A48|rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc	false	binding-associated region:101-132|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:O60749	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831.2|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303794|imex:IM-27647-75	intact-miscore:0.43	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000205302.7(gene)|ensembl:ENST00000379516.7(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990460""(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037918|mint:O60749|reactome:R-HSA-432722|refseq:NP_003091.2|refseq:NP_001265128.1|panther:PTHR10555(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606	intact-crc:E6BAADBDB96E0A48|rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc	false	binding-associated region:101-132|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9UNH7	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303794|imex:IM-27647-75	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	intact-crc:E6BAADBDB96E0A48|rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc	false	binding-associated region:101-132|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9Y5X3	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-715760|uniprotkb:Q52LC4|uniprotkb:B7ZKN3|uniprotkb:Q9BWP0|uniprotkb:D3DW26|uniprotkb:Q7KZN0|ensembl:ENSP00000366988.3|ensembl:ENSP00000366998.3	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx5_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303794|imex:IM-27647-75	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_055241.1|refseq:NP_689413.1|ensembl:ENSG00000089006.17(gene)|ensembl:ENST00000377759.9(transcript)|ensembl:ENST00000377768.7(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001891""(phagocytic cup)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006907""(pinocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010314""(phosphatidylinositol-5-phosphate binding)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0034452""(dynactin binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0045776""(negative regulation of blood pressure)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070685""(macropinocytic cup)|go:""GO:0080025""(phosphatidylinositol-3,5-bisphosphate binding)|go:""GO:0097422""(tubular endosome)|go:""GO:0098559""(cytoplasmic side of early endosome membrane)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|interpro:IPR042135|mint:Q9Y5X3|rcsb pdb:1SYS|rcsb pdb:5TGH|rcsb pdb:5TGI|rcsb pdb:5TGJ|rcsb pdb:5WY2|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6N5Z|rcsb pdb:8A1G|rcsb pdb:8ABQ|rcsb pdb:8AFZ|reactome:R-HSA-432722|panther:PTHR45850(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:VR2oUxQ4M2bm5zKeHQlao046QL09606	intact-crc:E6BAADBDB96E0A48|rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc	false	binding-associated region:101-132|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q86XE0	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-8099743|uniprotkb:Q8IW53|intact:MINT-8163285|intact:MINT-6940005|uniprotkb:Q96NG4|ensembl:ENSP00000310620.6	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx32_human(display_long)|uniprotkb:Sorting nexin-6B(gene name synonym)|uniprotkb:SNX32(gene name)|psi-mi:SNX32(display_short)|uniprotkb:SNX6B(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303794|imex:IM-27647-75	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_689973.2|panther:PTHR45850(orthology-group)|ensembl:ENSG00000172803.18(gene)|ensembl:ENST00000308342.7(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0015031""(protein transport)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR036871|mint:Q86XE0|rcsb pdb:6E8R"	-	-	function:May be involved in several stages of intracellular trafficking	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:I0+rJkFVm8v1eM51FMdsDBEFACc9606	intact-crc:E6BAADBDB96E0A48|rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc	false	binding-associated region:101-132|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q13888	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-1565170|uniprotkb:Q15570|uniprotkb:Q15571|uniprotkb:Q9BS41|ensembl:ENSP00000274400.5|ensembl:ENSP00000328901.6|ensembl:ENSP00000477954.1|ensembl:ENSP00000479262.1|ensembl:ENSP00000480548.1|ensembl:ENSP00000486014.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:tf2h2_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 2(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p44 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 44 kDa subunit(gene name synonym)|uniprotkb:GTF2H2(gene name)|psi-mi:GTF2H2(display_short)|uniprotkb:BTF2P44(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303794|imex:IM-27647-75	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_001506.1|panther:PTHR12695(orthology-group)|refseq:XP_016864894.1|refseq:XP_016864895.1|refseq:XP_016864892.1|refseq:XP_016864893.1|dip:DIP-786N|ensembl:ENSG00000145736.15(gene)|ensembl:ENSG00000275045.4(gene)|ensembl:ENSG00000276910.4(gene)|ensembl:ENST00000274400.10(transcript)|ensembl:ENST00000330280.11(transcript)|ensembl:ENST00000612581.4(transcript)|ensembl:ENST00000617228.4(transcript)|ensembl:ENST00000619997.4(transcript)|ensembl:ENST00000628423.2(transcript)|go:""GO:0000438""(core TFIIH complex portion of holo TFIIH complex)|go:""GO:0000439""(transcription factor TFIIH core complex)|go:""GO:0002031""(G protein-coupled receptor internalization)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005669""(transcription factor TFIID complex)|go:""GO:0005675""(transcription factor TFIIH holo complex)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006367""(transcription initiation at RNA polymerase II promoter)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009411""(response to UV)|go:""GO:0016251""(RNA polymerase II general transcription initiation factor activity)|go:""GO:0016607""(nuclear speck)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|interpro:IPR046349|mint:Q13888|rcsb pdb:1Z60|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7AD8|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|rcsb pdb:8BVW|rcsb pdb:8BYQ|rcsb pdb:8EBS|rcsb pdb:8EBT|rcsb pdb:8EBU|rcsb pdb:8EBV|rcsb pdb:8EBW|rcsb pdb:8EBX|rcsb pdb:8EBY|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8WAK|rcsb pdb:8WAL|rcsb pdb:8WAN|rcsb pdb:8WAO|rcsb pdb:8WAP|rcsb pdb:8WAQ|rcsb pdb:8WAR|rcsb pdb:8WAS|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:U4tPk4UlGiQz+exwhYG9kg7xGAM9606	intact-crc:E6BAADBDB96E0A48|rigid:koGrMfyrJ7DbrHfWOvpv0qJbyRc	false	binding-associated region:101-132|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:P04439	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155|ensembl:ENSP00000366005.5|ensembl:ENSP00000379873.1|ensembl:ENSP00000516612.1|ensembl:ENSP00000516614.1|ensembl:ENSP00000516616.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"efo:""Orphanet:179""|ensembl:ENSG00000206503.15(gene)|ensembl:ENST00000376809.10(transcript)|ensembl:ENST00000396634.5(transcript)|ensembl:ENST00000706901.1(transcript)|ensembl:ENST00000706903.1(transcript)|ensembl:ENST00000706905.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002419""(T cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002485""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0003723""(RNA binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0062061""(TAP complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2000568""(positive regulation of memory T cell activation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WJ5|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7MLE|rcsb pdb:7PHR|rcsb pdb:7QPD|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7STF|rcsb pdb:7UC5|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|rcsb pdb:8DVG|rcsb pdb:8RYM|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_001229687.1|refseq:NP_002107.3|ensembl:ENSP00000366005.5|ensembl:ENSP00000379873.1|ensembl:ENSP00000516612.1|ensembl:ENSP00000516614.1|ensembl:ENSP00000516616.1|panther:PTHR16675(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:P46531	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000148400.13(gene)|ensembl:ENST00000651671.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001554""(luteolysis)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001889""(liver development)|go:""GO:0001947""(heart looping)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0002085""(inhibition of neuroepithelial cell differentiation)|go:""GO:0002193""(MAML1-RBP-Jkappa- ICN1 complex)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003157""(endocardium development)|go:""GO:0003160""(endocardium morphogenesis)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003169""(coronary vein morphogenesis)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0003182""(coronary sinus valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003192""(mitral valve formation)|go:""GO:0003198""(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003207""(cardiac chamber formation)|go:""GO:0003208""(cardiac ventricle morphogenesis)|go:""GO:0003209""(cardiac atrium morphogenesis)|go:""GO:0003213""(cardiac right atrium morphogenesis)|go:""GO:0003214""(cardiac left ventricle morphogenesis)|go:""GO:0003219""(cardiac right ventricle formation)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003241""(growth involved in heart morphogenesis)|go:""GO:0003252""(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:""GO:0003270""(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:""GO:0003273""(cell migration involved in endocardial cushion formation)|go:""GO:0003332""(negative regulation of extracellular matrix constituent secretion)|go:""GO:0003344""(pericardium morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007221""(positive regulation of transcription of Notch receptor target)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007386""(compartment pattern specification)|go:""GO:0007411""(axon guidance)|go:""GO:0007440""(foregut morphogenesis)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009912""(auditory receptor cell fate commitment)|go:""GO:0009957""(epidermal cell fate specification)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010614""(negative regulation of cardiac muscle hypertrophy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010832""(negative regulation of myotube differentiation)|go:""GO:0014031""(mesenchymal cell development)|go:""GO:0014807""(regulation of somitogenesis)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0019899""(enzyme binding)|go:""GO:0021515""(cell differentiation in spinal cord)|go:""GO:0021915""(neural tube development)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030900""(forebrain development)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032966""(negative regulation of collagen biosynthetic process)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035148""(tube formation)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042670""(retinal cone cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045603""(positive regulation of endothelial cell differentiation)|go:""GO:0045608""(negative regulation of inner ear auditory receptor cell differentiation)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045955""(negative regulation of calcium ion-dependent exocytosis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046533""(negative regulation of photoreceptor cell differentiation)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0048103""(somatic stem cell division)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048711""(positive regulation of astrocyte differentiation)|go:""GO:0048715""(negative regulation of oligodendrocyte differentiation)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0055008""(cardiac muscle tissue morphogenesis)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060271""(cilium assembly)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0060354""(negative regulation of cell adhesion molecule production)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060528""(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:""GO:0060740""(prostate gland epithelium morphogenesis)|go:""GO:0060768""(regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:0060842""(arterial endothelial cell differentiation)|go:""GO:0060843""(venous endothelial cell differentiation)|go:""GO:0060948""(cardiac vascular smooth muscle cell development)|go:""GO:0060956""(endocardial cell differentiation)|go:""GO:0060979""(vasculogenesis involved in coronary vascular morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061101""(neuroendocrine cell differentiation)|go:""GO:0061344""(regulation of cell adhesion involved in heart morphogenesis)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0062043""(positive regulation of cardiac epithelial to mesenchymal transition)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0071372""(cellular response to follicle-stimulating hormone stimulus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072017""(distal tubule development)|go:""GO:0072044""(collecting duct development)|go:""GO:0072091""(regulation of stem cell proliferation)|go:""GO:0072144""(glomerular mesangial cell development)|go:""GO:0072148""(epithelial cell fate commitment)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0097400""(interleukin-17-mediated signaling pathway)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099565""(chemical synaptic transmission, postsynaptic)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:1901201""(regulation of extracellular matrix assembly)|go:""GO:1902263""(apoptotic process involved in embryonic digit morphogenesis)|go:""GO:1902339""(positive regulation of apoptotic process involved in morphogenesis)|go:""GO:1903849""(positive regulation of aorta morphogenesis)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2000974""(negative regulation of pro-B cell differentiation)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|rcsb pdb:1PB5|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:P46531|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|rcsb pdb:8OR5|rcsb pdb:8ORY|rcsb pdb:8ORZ|rcsb pdb:9B3G|rcsb pdb:9B3N|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|reactome:R-HSA-9818030|reactome:R-HSA-9818749|reactome:R-HSA-9824272|refseq:NP_060087.3|dip:DIP-29919N|efo:""Orphanet:402075""|efo:""Orphanet:974""|panther:PTHR45836(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:P11717	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-1048580|uniprotkb:Q7Z7G9|uniprotkb:Q96PT5|ensembl:ENSP00000349437.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:mpri_human(display_long)|uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym)|uniprotkb:Insulin-like growth factor II receptor(gene name synonym)|uniprotkb:M6P/IGF2 receptor(gene name synonym)|uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym)|uniprotkb:IGF2R(gene name)|psi-mi:IGF2R(display_short)|uniprotkb:MPRI(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_000867.2|ensembl:ENSG00000197081.16(gene)|ensembl:ENST00000356956.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001889""(liver development)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0001972""(retinoic acid binding)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005520""(insulin-like growth factor binding)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005641""(nuclear envelope lumen)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007165""(signal transduction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0009791""(post-embryonic development)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030118""(clathrin coat)|go:""GO:0030133""(transport vesicle)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031995""(insulin-like growth factor II binding)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904772""(response to tetrachloromethane)|go:""GO:1905394""(retromer complex binding)|interpro:IPR000479(Cation-independent mannose-6-phosphate receptor)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|interpro:IPR044865|mint:P11717|rcsb pdb:1E6F|rcsb pdb:1GP0|rcsb pdb:1GP3|rcsb pdb:1GQB|rcsb pdb:1JPL|rcsb pdb:1JWG|rcsb pdb:1LF8|rcsb pdb:2CNJ|rcsb pdb:2L29|rcsb pdb:2L2A|rcsb pdb:2M68|rcsb pdb:2M6T|rcsb pdb:2V5N|rcsb pdb:2V5O|rcsb pdb:2V5P|rcsb pdb:5IEI|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6P8I|rcsb pdb:6V02|rcsb pdb:6Z30|rcsb pdb:6Z31|rcsb pdb:6Z32|rcsb pdb:8AFZ|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-6027N|panther:PTHR15071(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:7lkG6WR8MQ/SONiTV/8g1ZTtKTU9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q04721	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-2652733|uniprotkb:Q5T3X7|uniprotkb:Q99734|uniprotkb:Q9H240|ensembl:ENSP00000256646.2	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:notc2_human(display_long)|uniprotkb:NOTCH2(gene name)|psi-mi:NOTCH2(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"efo:""Orphanet:261629""|efo:""Orphanet:955""|ensembl:ENSG00000134250.21(gene)|ensembl:ENST00000256646.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001709""(cell fate determination)|go:""GO:0001947""(heart looping)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0002315""(marginal zone B cell differentiation)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0006915""(apoptotic process)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007411""(axon guidance)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009986""(cell surface)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010838""(positive regulation of keratinocyte proliferation)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035622""(intrahepatic bile duct development)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042060""(wound healing)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043011""(myeloid dendritic cell differentiation)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0046849""(bone remodeling)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0060413""(atrial septum morphogenesis)|go:""GO:0060674""(placenta blood vessel development)|go:""GO:0061073""(ciliary body morphogenesis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0072014""(proximal tubule development)|go:""GO:0072015""(podocyte development)|go:""GO:0072104""(glomerular capillary formation)|go:""GO:0072574""(hepatocyte proliferation)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1990705""(cholangiocyte proliferation)|go:""GO:2001204""(regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022336|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:Q04721|rcsb pdb:2OO4|rcsb pdb:5MWB|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-2197563|reactome:R-HSA-2979096|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013695|refseq:NP_001186930.1|refseq:NP_077719.2|ensembl:ENSP00000256646.2|panther:PTHR45836(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:aXdQSGMwNJ7K0tA2kc3rRFysbIc9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q92729	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-7052301|uniprotkb:Q59HA4|intact:MINT-1349420|uniprotkb:Q5SYU5|uniprotkb:O00197|uniprotkb:A6H8L1|uniprotkb:P78399|uniprotkb:Q92735|uniprotkb:Q5SYU4|uniprotkb:Q92850|ensembl:ENSP00000334941.5	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:ptpru_human(display_long)|uniprotkb:PTPRU(gene name)|psi-mi:PTPRU(display_short)|uniprotkb:PCP2(gene name synonym)|uniprotkb:FMI(gene name synonym)|uniprotkb:PTPRO(gene name synonym)|uniprotkb:Receptor-type protein-tyrosine phosphatase psi(gene name synonym)|uniprotkb:Pancreatic carcinoma phosphatase 2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor omicron(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase J(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase pi(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_001181930.1|refseq:NP_005695.3|refseq:NP_573439.2|refseq:NP_573438.3|ensembl:ENSG00000060656.20(gene)|ensembl:ENST00000345512.7(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007185""(cell surface receptor protein tyrosine phosphatase signaling pathway)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031175""(neuron projection development)|go:""GO:0034109""(homotypic cell-cell adhesion)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:2000049""(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR051622|mint:Q92729|rcsb pdb:6SUB|rcsb pdb:6SUC|reactome:R-HSA-1433557|panther:PTHR19134(orthology-group)"	-	-	comment:mint|function:Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Forms complexes with beta-catenin and gamma-catenin/plakoglobin	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:zEYsgwn37ANdzpiq5f8h2TL+XD89606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:P00533	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-297353|uniprotkb:Q9BZS2|uniprotkb:Q9GZX1|uniprotkb:Q9H2C9|uniprotkb:Q9H3C9|uniprotkb:Q9UMD7|uniprotkb:Q9UMD8|uniprotkb:Q9UMG5|uniprotkb:O00688|uniprotkb:O00732|uniprotkb:P06268|uniprotkb:Q14225|uniprotkb:Q92795|intact:EBI-28985169|uniprotkb:Q68GS5|ensembl:ENSP00000275493.2	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:egfr_human(display_long)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:ERBB(gene name synonym)|uniprotkb:HER1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000146648.21(gene)|ensembl:ENST00000275493.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001503""(ossification)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001942""(hair follicle development)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007435""(salivary gland morphogenesis)|go:""GO:0007494""(midgut development)|go:""GO:0007611""(learning or memory)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016101""(diterpenoid metabolic process)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0022008""(neurogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0033594""(response to hydroxyisoflavone)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038134""(ERBB2-EGFR signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042311""(vasodilation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042698""(ovulation cycle)|go:""GO:0042743""(hydrogen peroxide metabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0043586""(tongue development)|go:""GO:0045121""(membrane raft)|go:""GO:0045296""(cadherin binding)|go:""GO:0045737""(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048143""(astrocyte activation)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048408""(epidermal growth factor binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048546""(digestive tract morphogenesis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051015""(actin filament binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051205""(protein insertion into membrane)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051968""(positive regulation of synaptic transmission, glutamatergic)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060571""(morphogenesis of an epithelial fold)|go:""GO:0061029""(eyelid development in camera-type eye)|go:""GO:0070141""(response to UV-A)|go:""GO:0070257""(positive regulation of mucus secretion)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070435""(Shc-EGFR complex)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097421""(liver regeneration)|go:""GO:0097489""(multivesicular body, internal vesicle lumen)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900020""(positive regulation of protein kinase C activity)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|go:""GO:1902722""(positive regulation of prolactin secretion)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905208""(negative regulation of cardiocyte differentiation)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|interpro:IPR049328|interpro:IPR050122|mint:P00533|rcsb pdb:1IVO|rcsb pdb:1M14|rcsb pdb:1M17|rcsb pdb:1MOX|rcsb pdb:1NQL|rcsb pdb:1XKK|rcsb pdb:1YY9|rcsb pdb:1Z9I|rcsb pdb:2EB2|rcsb pdb:2EB3|rcsb pdb:2GS2|rcsb pdb:2GS6|rcsb pdb:2GS7|rcsb pdb:2ITN|rcsb pdb:2ITO|rcsb pdb:2ITP|rcsb pdb:2ITQ|rcsb pdb:2ITT|rcsb pdb:2ITU|rcsb pdb:2ITV|rcsb pdb:2ITW|rcsb pdb:2ITX|rcsb pdb:2ITY|rcsb pdb:2ITZ|rcsb pdb:2KS1|rcsb pdb:2J5E|rcsb pdb:2J5F|rcsb pdb:2J6M|rcsb pdb:2JIT|rcsb pdb:2JIU|rcsb pdb:2JIV|rcsb pdb:2M0B|rcsb pdb:2M20|rcsb pdb:2N5S|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:2RGP|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BEL|rcsb pdb:3BUO|rcsb pdb:3C09|rcsb pdb:3G5V|rcsb pdb:3G5Y|rcsb pdb:3GOP|rcsb pdb:3GT8|rcsb pdb:3IKA|rcsb pdb:3LZB|rcsb pdb:3NJP|rcsb pdb:3OB2|rcsb pdb:3OP0|rcsb pdb:3P0Y|rcsb pdb:3PFV|rcsb pdb:3POZ|rcsb pdb:3QWQ|rcsb pdb:3UG1|rcsb pdb:3UG2|rcsb pdb:3VJN|rcsb pdb:3VJO|rcsb pdb:3VRP|rcsb pdb:3VRR|rcsb pdb:3W2O|rcsb pdb:3W2P|rcsb pdb:3W2Q|rcsb pdb:3W2R|rcsb pdb:3W2S|rcsb pdb:3W32|rcsb pdb:3W33|rcsb pdb:4G5J|rcsb pdb:4G5P|rcsb pdb:4HJO|rcsb pdb:4I1Z|rcsb pdb:4I20|rcsb pdb:4I21|rcsb pdb:4I22|rcsb pdb:4I23|rcsb pdb:4I24|rcsb pdb:4JQ7|rcsb pdb:4JQ8|rcsb pdb:4JR3|rcsb pdb:4JRV|rcsb pdb:4KRL|rcsb pdb:4KRM|rcsb pdb:4KRO|rcsb pdb:4KRP|rcsb pdb:4LI5|rcsb pdb:4LL0|rcsb pdb:4LQM|rcsb pdb:4LRM|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4R5S|rcsb pdb:4RIW|rcsb pdb:4RIX|rcsb pdb:4RIY|rcsb pdb:4RJ4|rcsb pdb:4RJ5|rcsb pdb:4RJ6|rcsb pdb:4RJ7|rcsb pdb:4RJ8|rcsb pdb:4TKS|rcsb pdb:4UIP|rcsb pdb:4UV7|rcsb pdb:4WD5|rcsb pdb:4WKQ|rcsb pdb:4WRG|rcsb pdb:4ZAU|rcsb pdb:4ZJV|rcsb pdb:4ZSE|rcsb pdb:5C8K|rcsb pdb:5C8M|rcsb pdb:5C8N|rcsb pdb:5CAL|rcsb pdb:5CAN|rcsb pdb:5CAO|rcsb pdb:5CAP|rcsb pdb:5CAQ|rcsb pdb:5CAS|rcsb pdb:5CAU|rcsb pdb:5CAV|rcsb pdb:5CNN|rcsb pdb:5CNO|rcsb pdb:5CZH|rcsb pdb:5CZI|rcsb pdb:5D41|rcsb pdb:5EDP|rcsb pdb:5EDQ|rcsb pdb:5EDR|rcsb pdb:5EM5|rcsb pdb:5EM6|rcsb pdb:5EM7|rcsb pdb:5EM8|rcsb pdb:5FED|rcsb pdb:5FEE|rcsb pdb:5FEQ|rcsb pdb:5GMP|rcsb pdb:5GNK|rcsb pdb:5GTY|rcsb pdb:5GTZ|rcsb pdb:5HCX|rcsb pdb:5HCY|rcsb pdb:5HCZ|rcsb pdb:5HG5|rcsb pdb:5HG7|rcsb pdb:5HG8|rcsb pdb:5HG9|rcsb pdb:5HIB|rcsb pdb:5HIC|rcsb pdb:5J9Y|rcsb pdb:5J9Z|rcsb pdb:5JEB|rcsb pdb:5LV6|rcsb pdb:5SX4|rcsb pdb:5SX5|rcsb pdb:5U8L|rcsb pdb:5UG8|rcsb pdb:5UG9|rcsb pdb:5UGA|rcsb pdb:5UGB|rcsb pdb:5UGC|rcsb pdb:5UWD|rcsb pdb:5WB7|rcsb pdb:5WB8|rcsb pdb:5X26|rcsb pdb:5X27|rcsb pdb:5X28|rcsb pdb:5X2A|rcsb pdb:5X2C|rcsb pdb:5X2F|rcsb pdb:5X2K|rcsb pdb:5XDK|rcsb pdb:5XDL|rcsb pdb:5XGM|rcsb pdb:5XGN|rcsb pdb:5XWD|rcsb pdb:5Y25|rcsb pdb:5Y9T|rcsb pdb:5YU9|rcsb pdb:5ZTO|rcsb pdb:5ZWJ|rcsb pdb:6ARU|rcsb pdb:6B3S|rcsb pdb:6D8E|rcsb pdb:6DUK|rcsb pdb:6JRJ|rcsb pdb:6JRK|rcsb pdb:6JRX|rcsb pdb:6JWL|rcsb pdb:6JX0|rcsb pdb:6JX4|rcsb pdb:6JXT|rcsb pdb:6JZ0|rcsb pdb:6LUB|rcsb pdb:6LUD|rcsb pdb:6P1D|rcsb pdb:6P1L|rcsb pdb:6P8Q|rcsb pdb:6S89|rcsb pdb:6S8A|rcsb pdb:6S9B|rcsb pdb:6S9C|rcsb pdb:6S9D|rcsb pdb:6TFU|rcsb pdb:6TFV|rcsb pdb:6TFW|rcsb pdb:6TFY|rcsb pdb:6TFZ|rcsb pdb:6TG0|rcsb pdb:6TG1|rcsb pdb:6V5N|rcsb pdb:6V5P|rcsb pdb:6V66|rcsb pdb:6V6K|rcsb pdb:6V6O|rcsb pdb:6VH4|rcsb pdb:6VHN|rcsb pdb:6VHP|rcsb pdb:6WA2|rcsb pdb:6WAK|rcsb pdb:6WXN|rcsb pdb:6XL4|rcsb pdb:6Z4B|rcsb pdb:6Z4D|rcsb pdb:7A2A|rcsb pdb:7A6I|rcsb pdb:7A6J|rcsb pdb:7A6K|rcsb pdb:7AEI|rcsb pdb:7AEM|rcsb pdb:7B85|rcsb pdb:7ER2|rcsb pdb:7JXI|rcsb pdb:7JXK|rcsb pdb:7JXL|rcsb pdb:7JXM|rcsb pdb:7JXP|rcsb pdb:7JXQ|rcsb pdb:7JXW|rcsb pdb:7K1H|rcsb pdb:7K1I|rcsb pdb:7KXZ|rcsb pdb:7KY0|rcsb pdb:7LEN|rcsb pdb:7LFR|rcsb pdb:7LFS|rcsb pdb:7LG8|rcsb pdb:7LGS|rcsb pdb:7LTX|rcsb pdb:7OM4|rcsb pdb:7OXB|rcsb pdb:7SI1|rcsb pdb:7SYD|rcsb pdb:7SYE|rcsb pdb:7SZ0|rcsb pdb:7SZ1|rcsb pdb:8A2B|rcsb pdb:7SZ5|rcsb pdb:7SZ7|rcsb pdb:7T4I|rcsb pdb:7T4J|rcsb pdb:7TVD|rcsb pdb:7U98|rcsb pdb:7U99|rcsb pdb:7U9A|rcsb pdb:7UKV|rcsb pdb:7UKW|rcsb pdb:7VRA|rcsb pdb:7VRE|rcsb pdb:7ZYM|rcsb pdb:7ZYN|rcsb pdb:7ZYP|rcsb pdb:7ZYQ|rcsb pdb:8A27|rcsb pdb:8A2A|rcsb pdb:8A2D|rcsb pdb:8D73|rcsb pdb:8D76|rcsb pdb:8DSW|rcsb pdb:8EME|rcsb pdb:8F1H|rcsb pdb:8F1W|rcsb pdb:8F1X|rcsb pdb:8F1Y|rcsb pdb:8F1Z|rcsb pdb:8FV3|rcsb pdb:8FV4|rcsb pdb:8G63|rcsb pdb:8GB4|rcsb pdb:8GK5|rcsb pdb:8H7X|rcsb pdb:8HGO|rcsb pdb:8HGP|rcsb pdb:8HGS|rcsb pdb:8HV1|rcsb pdb:8HV2|rcsb pdb:8HV3|rcsb pdb:8HV4|rcsb pdb:8HV5|rcsb pdb:8HV6|rcsb pdb:8HV7|rcsb pdb:8HV8|rcsb pdb:8HV9|rcsb pdb:8HVA|rcsb pdb:8HY7|rcsb pdb:8KFQ|rcsb pdb:8PNZ|rcsb pdb:8PO0|rcsb pdb:8PO1|rcsb pdb:8PO2|rcsb pdb:8PO3|rcsb pdb:8PO4|rcsb pdb:8S1M|rcsb pdb:8SC7|rcsb pdb:8TJL|rcsb pdb:8TO3|rcsb pdb:8TO4|rcsb pdb:8UKV|rcsb pdb:8UKW|rcsb pdb:8UKX|rcsb pdb:8WD4|rcsb pdb:9EWT|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-212718|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-445144|reactome:R-HSA-5637810|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8857538|reactome:R-HSA-8863795|reactome:R-HSA-8866910|reactome:R-HSA-9009391|reactome:R-HSA-9013507|reactome:R-HSA-9609690|reactome:R-HSA-9634638|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9820960|refseq:NP_005219.2|refseq:NP_958439.1|refseq:NP_958440.1|refseq:NP_958441.1|dip:DIP-405N|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:294023""|ensembl:ENSP00000275493.2|ensembl:ENST00000342916.7|ensembl:ENSP00000342376.3|ensembl:ENST00000344576.7|ensembl:ENSP00000345973.2|ensembl:ENST00000420316.6|ensembl:ENSP00000413843.2|panther:PTHR24416(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:gXB5slVTC+z8DdqqXIzXG7lDwk09606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9Y2J2	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158.2|uniprotkb:B7Z4I5|uniprotkb:F5GX05	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397.18(gene)|ensembl:ENST00000341928.7(transcript)|go:""GO:0002175""(protein localization to paranode region of axon)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006915""(apoptotic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0030054""(cell junction)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0030913""(paranodal junction assembly)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0033270""(paranode region of axon)|go:""GO:0043217""(myelin maintenance)|go:""GO:0044224""(juxtaparanode region of axon)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0071205""(protein localization to juxtaparanode region of axon)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098696""(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0106006""(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847(""FERM adjacent (FA)"")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N|panther:PTHR23280(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:P19022	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-2256711|uniprotkb:Q14923|uniprotkb:Q8N173|uniprotkb:B0YIY6|uniprotkb:A8MWK3|intact:EBI-40264067|ensembl:ENSP00000269141.3|intact:EBI-28986933	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:cadh2_human(display_long)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short)|uniprotkb:CDHN(gene name synonym)|uniprotkb:NCAD(gene name synonym)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDw325(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"dip:DIP-43894N|efo:""Orphanet:293910""|ensembl:ENSG00000170558.10(gene)|ensembl:ENST00000269141.8(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003323""(type B pancreatic cell development)|go:""GO:0003723""(RNA binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007416""(synapse assembly)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009986""(cell surface)|go:""GO:0010001""(glial cell differentiation)|go:""GO:0014032""(neural crest cell development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0014704""(intercalated disc)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0016339""(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030057""(desmosome)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035995""(detection of muscle stretch)|go:""GO:0042383""(sarcolemma)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045177""(apical part of cell)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048514""(blood vessel morphogenesis)|go:""GO:0048787""(presynaptic active zone membrane)|go:""GO:0048854""(brain morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0060019""(radial glial cell differentiation)|go:""GO:0060563""(neuroepithelial cell differentiation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070445""(regulation of oligodendrocyte progenitor proliferation)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0090497""(mesenchymal cell migration)|go:""GO:0097091""(synaptic vesicle clustering)|go:""GO:0097118""(neuroligin clustering involved in postsynaptic membrane assembly)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0099634""(postsynaptic specialization membrane)|go:""GO:1902897""(regulation of postsynaptic density protein 95 clustering)|go:""GO:2000809""(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|mint:P19022|reactome:R-HSA-381426|reactome:R-HSA-418990|reactome:R-HSA-525793|reactome:R-HSA-8957275|refseq:NP_001295105.1|refseq:NP_001783.2|panther:PTHR24027(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:lo+u8oH3T9OYU56F5MgXKmwEhuI9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q14574	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-6163585|intact:EBI-28985956|uniprotkb:A6NN35|uniprotkb:Q14200|uniprotkb:Q9HAZ9|ensembl:ENSP00000353608.4	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:dsc3_human(display_long)|uniprotkb:Cadherin family member 3(gene name synonym)|uniprotkb:DSC4(gene name synonym)|uniprotkb:Desmocollin-4(gene name synonym)|uniprotkb:HT-CP(gene name synonym)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:CDHF3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000134762.17(gene)|ensembl:ENST00000360428.9(transcript)|go:""GO:0001533""(cornified envelope)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0016020""(membrane)|go:""GO:0030054""(cell junction)|go:""GO:0030057""(desmosome)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR050971|mint:Q14574|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_001932.2|refseq:NP_077741.2|efo:""Orphanet:217407""|panther:PTHR24025(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:2En63we0WgDfQQY2f4qQHK/clSI9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q68DH5	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-20858131|uniprotkb:B3KRB6|uniprotkb:Q9NTC7|ensembl:ENSP00000296603.4	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:lmbd2_human(display_long)|uniprotkb:LMBRD2(gene name)|psi-mi:LMBRD2(display_short)|uniprotkb:LMBR1 domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"efo:""Orphanet:528084""|panther:PTHR21355(orthology-group)|ensembl:ENSG00000164187.7(gene)|ensembl:ENST00000296603.5(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0071875""(adrenergic receptor signaling pathway)|interpro:IPR006876(LMBR1-like conserved region)|interpro:IPR051584|mint:Q68DH5|refseq:NP_001007528.1|refseq:XP_011512464.1"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:q2WB24Dd8SLHl38AcRDvDE/k8zs9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q5VV42	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695.4|ensembl:ENSP00000367873.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	"psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:""tRNA-t(6)A37 methylthiotransferase""(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_060244.2|ensembl:ENSG00000145996.11(gene)|ensembl:ENST00000274695.8(transcript)|ensembl:ENST00000378610.1(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0016020""(membrane)|go:""GO:0035598""(""tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase activity"")|go:""GO:0035600""(tRNA methylthiolation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0061712""(""obsolete tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase"")|go:""GO:1990145""(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315|panther:PTHR11918(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q04206	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-73886|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1|ensembl:ENSP00000384273.3	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"panther:PTHR24169(orthology-group)|efo:""Orphanet:530792""|dip:DIP-24238N|efo:""Orphanet:596759""|ensembl:ENSG00000173039.20(gene)|ensembl:ENST00000406246.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001889""(liver development)|go:""GO:0001942""(hair follicle development)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006117""(acetaldehyde metabolic process)|go:""GO:0006325""(chromatin organization)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007218""(neuropeptide signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010224""(response to UV-B)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014040""(positive regulation of Schwann cell differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030163""(protein catabolic process)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032570""(response to progesterone)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032868""(response to insulin)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0034097""(response to cytokine)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0038084""(vascular endothelial growth factor signaling pathway)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038161""(prolactin signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042277""(peptide binding)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042805""(actinin binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051607""(defense response to virus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071159""(NF-kappaB complex)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071224""(cellular response to peptidoglycan)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071532""(ankyrin repeat binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099527""(postsynapse to nucleus signaling pathway)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIW|rcsb pdb:7BIY|rcsb pdb:7BJB|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7LET|rcsb pdb:7LEU|rcsb pdb:7LF4|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NMH|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001138610.1|refseq:NP_001230913.1|refseq:NP_068810.3|ensembl:ENST00000308639.13|ensembl:ENSP00000311508.9|ensembl:ENSP00000384273.3"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q13596	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.43	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528.15(gene)|ensembl:ENST00000559844.6(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990460""(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|interpro:IPR036871|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|rcsb pdb:8A1G|rcsb pdb:8ABQ|rcsb pdb:8AFZ|dip:DIP-398N|panther:PTHR10555(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:O60749	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831.2|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.43	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000205302.7(gene)|ensembl:ENST00000379516.7(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990460""(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037918|mint:O60749|reactome:R-HSA-432722|refseq:NP_003091.2|refseq:NP_001265128.1|panther:PTHR10555(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9BY67	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-5652260|uniprotkb:Q86WB8|uniprotkb:Q8N2F4|uniprotkb:A4FVB5|uniprotkb:F5H0J4|uniprotkb:H0YGA7|uniprotkb:H1ZZV9|uniprotkb:H1ZZW1|uniprotkb:H1ZZW2|uniprotkb:X5D2C8|ensembl:ENSP00000395359.2	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:cadm1_human(display_long)|uniprotkb:IGSF4A(gene name synonym)|uniprotkb:CADM1(gene name)|psi-mi:CADM1(display_short)|uniprotkb:IGSF4(gene name synonym)|uniprotkb:NECL2(gene name synonym)|uniprotkb:SYNCAM(gene name synonym)|uniprotkb:TSLC1(gene name synonym)|uniprotkb:Immunoglobulin superfamily member 4(gene name synonym)|uniprotkb:Nectin-like protein 2(gene name synonym)|uniprotkb:Spermatogenic immunoglobulin superfamily(gene name synonym)|uniprotkb:Synaptic cell adhesion molecule(gene name synonym)|uniprotkb:Tumor suppressor in lung cancer 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_001091987.1|refseq:NP_055148.3|dip:DIP-57599N|refseq:NP_001287972.1|refseq:NP_001287973.1|refseq:NP_001287974.1|ensembl:ENSG00000182985.19(gene)|ensembl:ENST00000452722.7(transcript)|go:""GO:0001819""(positive regulation of cytokine production)|go:""GO:0001889""(liver development)|go:""GO:0002376""(immune system process)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006915""(apoptotic process)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008037""(cell recognition)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030425""(dendrite)|go:""GO:0042271""(susceptibility to natural killer cell mediated cytotoxicity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043005""(neuron projection)|go:""GO:0045202""(synapse)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051606""(detection of stimulus)|go:""GO:0120154""(negative regulation of ERBB4 signaling pathway)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9BY67|rcsb pdb:3BIN|rcsb pdb:4H5S|reactome:R-HSA-418990|reactome:R-HSA-420597|panther:PTHR45889(orthology-group)"	-	-	crc64:CDEDE1E0C08BDD3A	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:870cLsl7OEZV3iLs+IaE2V/UW4o9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9UNH7	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9Y5X3	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-715760|uniprotkb:Q52LC4|uniprotkb:B7ZKN3|uniprotkb:Q9BWP0|uniprotkb:D3DW26|uniprotkb:Q7KZN0|ensembl:ENSP00000366988.3|ensembl:ENSP00000366998.3	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx5_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_055241.1|refseq:NP_689413.1|ensembl:ENSG00000089006.17(gene)|ensembl:ENST00000377759.9(transcript)|ensembl:ENST00000377768.7(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001891""(phagocytic cup)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006907""(pinocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010314""(phosphatidylinositol-5-phosphate binding)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0034452""(dynactin binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0045776""(negative regulation of blood pressure)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070685""(macropinocytic cup)|go:""GO:0080025""(phosphatidylinositol-3,5-bisphosphate binding)|go:""GO:0097422""(tubular endosome)|go:""GO:0098559""(cytoplasmic side of early endosome membrane)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|interpro:IPR042135|mint:Q9Y5X3|rcsb pdb:1SYS|rcsb pdb:5TGH|rcsb pdb:5TGI|rcsb pdb:5TGJ|rcsb pdb:5WY2|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6N5Z|rcsb pdb:8A1G|rcsb pdb:8ABQ|rcsb pdb:8AFZ|reactome:R-HSA-432722|panther:PTHR45850(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:VR2oUxQ4M2bm5zKeHQlao046QL09606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:P30447	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-1046240|uniprotkb:Q9TQF1|uniprotkb:Q9TQF8|uniprotkb:Q9TQG5|uniprotkb:Q9TQM6	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:1a23_human(display_long)|uniprotkb:MHC class I antigen A*23(gene name synonym)|uniprotkb:HLA class I histocompatibility antigen, A-9 alpha chain(gene name synonym)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"go:""GO:0042612""(MHC class I protein complex)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|ensembl:ENST00000454091|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0009986""(cell surface)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0042605""(peptide antigen binding)|ensembl:ENSG00000223980|ensembl:ENSP00000410645|go:""GO:0000139""(Golgi membrane)|go:""GO:0002479""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:""GO:0002480""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:""GO:0005886""(plasma membrane)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0050776""(regulation of immune response)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0071556""(obsolete integral component of lumenal side of endoplasmic reticulum membrane)|go:""GO:0002474""(antigen processing and presentation of peptide antigen via MHC class I)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0055038""(recycling endosome membrane)|interpro:IPR036179|interpro:IPR037055"	-	-	no-uniprot-update:This interactor won't be updated using Uniprot.	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:RuTq2GS3tPQEFt5Pbhm5IOpWa0Y9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q12907	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-3915406|uniprotkb:Q53HH1|ensembl:ENSP00000303366.7	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:lman2_human(display_long)|uniprotkb:LMAN2(gene name)|psi-mi:LMAN2(display_short)|uniprotkb:C5orf8(gene name synonym)|uniprotkb:Glycoprotein GP36b(gene name synonym)|uniprotkb:Lectin mannose-binding 2(gene name synonym)|uniprotkb:Vesicular integral-membrane protein 36(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_006807.1|ensembl:ENSG00000169223.16(gene)|ensembl:ENST00000303127.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035664|interpro:IPR051136|mint:Q12907|reactome:R-HSA-204005|reactome:R-HSA-5694530|panther:PTHR12223(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:goqUZGW9/lvVMWDAZS9csH3TqWY9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:P98172	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-538287|uniprotkb:D3DVU0|ensembl:ENSP00000204961.4	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:efnb1_human(display_long)|uniprotkb:EPH-related receptor tyrosine kinase ligand 2(gene name synonym)|uniprotkb:EFL3(gene name synonym)|uniprotkb:EFNB1(gene name)|psi-mi:EFNB1(display_short)|uniprotkb:EFL-3(gene name synonym)|uniprotkb:EPLG2(gene name synonym)|uniprotkb:LERK2(gene name synonym)|uniprotkb:ELK ligand(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"panther:PTHR11304(orthology-group)|ensembl:ENSG00000090776.6(gene)|ensembl:ENST00000204961.5(transcript)|go:""GO:0001755""(neural crest cell migration)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007411""(axon guidance)|go:""GO:0009880""(embryonic pattern specification)|go:""GO:0009986""(cell surface)|go:""GO:0031295""(T cell costimulation)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P98172|rcsb pdb:6THG|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|refseq:NP_004420.1|efo:""Orphanet:1520"""	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:s9RYPWXKQ2QMzvfGluiliH3YC3s9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9P2W9	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-725334|uniprotkb:Q596L3|uniprotkb:Q5TZP5|ensembl:ENSP00000305810.2	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:stx18_human(display_long)|uniprotkb:Cell growth-inhibiting gene 9 protein(gene name synonym)|uniprotkb:STX18(gene name)|psi-mi:STX18(display_short)|uniprotkb:GIG9(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_058626.1|refseq:NP_001333211.1|refseq:NP_001333210.1|refseq:NP_001333229.1|dip:DIP-37617N|ensembl:ENSG00000168818.10(gene)|ensembl:ENST00000306200.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031201""(SNARE complex)|go:""GO:0090158""(endoplasmic reticulum membrane organization)|go:""GO:1902117""(positive regulation of organelle assembly)|go:""GO:1902953""(positive regulation of ER to Golgi vesicle-mediated transport)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR019529|mint:Q9P2W9|reactome:R-HSA-6811434|panther:PTHR15959(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:QpvkckDM1D5Jaty6AmK3vEwRZts9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9UET6	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-1055987|uniprotkb:O75670|uniprotkb:B2RCJ0|ensembl:ENSP00000326948.2	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:trm7_human(display_long)|uniprotkb:FTSJ1(gene name)|psi-mi:FTSJ1(display_short)|uniprotkb:JM23(orf name)|uniprotkb:Protein ftsJ homolog 1(gene name synonym)|uniprotkb:2'-O-ribose RNA methyltransferase TRM7 homolog(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000068438.15(gene)|ensembl:ENST00000348411.3(transcript)|go:""GO:0002128""(tRNA nucleoside ribose methylation)|go:""GO:0002130""(wobble position ribose methylation)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006400""(tRNA modification)|go:""GO:0008175""(tRNA methyltransferase activity)|go:""GO:0016423""(""tRNA (guanine) methyltransferase activity"")|go:""GO:0022008""(neurogenesis)|go:""GO:0030488""(tRNA methylation)|go:""GO:0106050""(tRNA 2'-O-methyltransferase activity)|go:""GO:0106340""(""tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase activity"")|go:""GO:1904047""(S-adenosyl-L-methionine binding)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR028590|interpro:IPR029063|interpro:IPR050082|mint:Q9UET6|reactome:R-HSA-6782315|refseq:NP_001269086.1|refseq:NP_036412.1|refseq:NP_803188.1|refseq:XP_005272652.1|efo:""Orphanet:777""|panther:PTHR10920(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:N4L9nsU0Wj3FMVjYALdxpx56aZs9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9Y6I9	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-10329860|uniprotkb:Q9UKD7|uniprotkb:B3KN87|ensembl:ENSP00000340969.5|ensembl:ENSP00000378497.1|ensembl:ENSP00000396628.1|ensembl:ENSP00000398802.1|ensembl:ENSP00000408186.1|ensembl:ENSP00000477946.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:tx264_human(display_long)|uniprotkb:TEX264(gene name)|psi-mi:TEX264(display_short)|uniprotkb:Putative secreted protein Zsig11(gene name synonym)|uniprotkb:ZSIG11(gene name synonym)|uniprotkb:UNQ337/PRO536(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:XP_011532107.1|refseq:NP_001123356.1|refseq:NP_001230654.1|refseq:NP_001230655.1|refseq:NP_001230656.1|refseq:NP_001265124.1|refseq:NP_057010.1|refseq:XP_006713258.1|refseq:XP_006713260.1|ensembl:ENSG00000164081.13(gene)|ensembl:ENST00000341333.10(transcript)|ensembl:ENST00000395057.5(transcript)|ensembl:ENST00000415259.5(transcript)|ensembl:ENST00000416589.5(transcript)|ensembl:ENST00000457573.5(transcript)|ensembl:ENST00000611400.4(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005657""(replication fork)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0061709""(reticulophagy)|go:""GO:0106300""(protein-DNA covalent cross-linking repair)|interpro:IPR011256(Regulatory factor, effector, bacterial)|mint:Q9Y6I9|rcsb pdb:7VEC|rcsb pdb:7VED|reactome:R-HSA-114608|panther:PTHR15949(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:Agv5w3SF9VdUL0o2qXZ7erRtyJ09606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q86Y82	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-2691717|uniprotkb:B1AJQ7|uniprotkb:O95564|ensembl:ENSP00000363054.4	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:stx12_human(display_long)|uniprotkb:STX12(gene name)|psi-mi:STX12(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_803173.1|dip:DIP-44225N|ensembl:ENSG00000117758.14(gene)|ensembl:ENST00000373943.9(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000149""(SNARE binding)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0012505""(endomembrane system)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032456""(endocytic recycling)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045121""(membrane raft)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048278""(vesicle docking)|go:""GO:0050821""(protein stabilization)|go:""GO:0055037""(recycling endosome)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0098837""(postsynaptic recycling endosome)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR045242|mint:Q86Y82|rcsb pdb:2DNX|panther:PTHR19957(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:kSTOaE08HK8SpI19dBZRZbOVCGw9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9NUM4	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-10490807|uniprotkb:Q53FL9|uniprotkb:A4D108|uniprotkb:Q8N4L0|ensembl:ENSP00000379901.2|ensembl:ENSP00000379902.3|ensembl:ENSP00000401302.2|ensembl:ENSP00000515905.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:t106b_human(display_long)|uniprotkb:TMEM106B(gene name)|psi-mi:TMEM106B(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000106460.20(gene)|ensembl:ENST00000396667.7(transcript)|ensembl:ENST00000396668.8(transcript)|ensembl:ENST00000444443.6(transcript)|ensembl:ENST00000704455.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0007040""(lysosome organization)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032418""(lysosome localization)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0051117""(ATPase binding)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:1900006""(positive regulation of dendrite development)|go:""GO:1905146""(lysosomal protein catabolic process)|go:""GO:1905671""(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)|interpro:IPR048509|interpro:IPR048511|mint:Q9NUM4|rcsb pdb:7QVC|rcsb pdb:7QVF|rcsb pdb:7QWG|rcsb pdb:7QWL|rcsb pdb:7QWM|rcsb pdb:7SAQ|rcsb pdb:7SAR|rcsb pdb:7SAS|rcsb pdb:7TMC|rcsb pdb:7U10|rcsb pdb:7U11|rcsb pdb:7U12|rcsb pdb:7U13|rcsb pdb:7U14|rcsb pdb:7U15|rcsb pdb:7U16|rcsb pdb:7U17|rcsb pdb:7U18|rcsb pdb:7X83|rcsb pdb:7X84|rcsb pdb:8B7D|rcsb pdb:8F9K|rcsb pdb:8J7N|rcsb pdb:8J7P|rcsb pdb:8OTD|rcsb pdb:8OTE|refseq:NP_001127704.1|refseq:NP_060844.2|refseq:XP_005249846.1|efo:""Orphanet:100070""|efo:""Orphanet:100069""|efo:""Orphanet:275864""|ensembl:ENSP00000379901.2|ensembl:ENSP00000379902.3|ensembl:ENSP00000401302.2|ensembl:ENSP00000515905.1|panther:PTHR28556(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:RdOP7hFA+H8Tjb/iLZrdShpfJmg9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q8IY95	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-4324723|uniprotkb:Q7Z3A1|uniprotkb:Q8N928|ensembl:ENSP00000305069.4	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:tm192_human(display_long)|uniprotkb:TMEM192(gene name)|psi-mi:TMEM192(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_001093859.1|ensembl:ENSG00000170088.14(gene)|ensembl:ENST00000306480.11(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005770""(late endosome)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR029399|mint:Q8IY95|panther:PTHR31592(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:b2RQelAEDWcwiZ0w8/tgiEmeBX09606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:O15400	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-3221827|uniprotkb:Q5SZW2|uniprotkb:Q96ES9|uniprotkb:E1P579|ensembl:ENSP00000356918.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:stx7_human(display_long)|uniprotkb:STX7(gene name)|psi-mi:STX7(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:XP_011534480.1|refseq:NP_003560.2|refseq:NP_001313507.1|refseq:NP_001313508.1|refseq:NP_001313509.1|dip:DIP-57384N|go:""GO:0005765""(lysosomal membrane)|ensembl:ENSG00000079950.14(gene)|ensembl:ENST00000367941.7(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0012505""(endomembrane system)|go:""GO:0019869""(chloride channel inhibitor activity)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031201""(SNARE complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0042582""(azurophil granule)|go:""GO:0048278""(vesicle docking)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051640""(organelle localization)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070820""(tertiary granule)|go:""GO:0070925""(organelle assembly)|go:""GO:1902685""(positive regulation of receptor localization to synapse)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR045242|mint:O15400|panther:PTHR19957(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:lFaq26g0qeP7ObMMKexuZamQgps9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9NNW5	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:wdr6_human(display_long)|uniprotkb:WD repeat-containing protein 6(gene name synonym)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_060501.3|panther:PTHR14344(orthology-group)|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252.19(gene)|ensembl:ENST00000608424.6(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002130""(wobble position ribose methylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0030488""(tRNA methylation)|go:""GO:0070314""(G1 to G0 transition)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR051973|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9Y2U8	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-2561428|uniprotkb:Q9NT47|uniprotkb:Q9NYA5|ensembl:ENSP00000308369.2|intact:EBI-40264392	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:man1_human(display_long)|uniprotkb:MAN1(gene name synonym)|uniprotkb:LEM domain-containing protein 3(gene name synonym)|uniprotkb:LEMD3(gene name)|psi-mi:LEMD3(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000174106.3(gene)|ensembl:ENST00000308330.3(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0016020""(membrane)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032926""(negative regulation of activin receptor signaling pathway)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018996|interpro:IPR034394|interpro:IPR035979|interpro:IPR041885|interpro:IPR052277|mint:Q9Y2U8|rcsb pdb:2CH0|rcsb pdb:5ZOJ|rcsb pdb:5ZOK|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001161086.1|refseq:NP_055134.2|efo:""Orphanet:166119""|efo:""Orphanet:1879""|efo:""Orphanet:94063""|panther:PTHR48036(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:8AILzxAZLbxCAzlJ7oPg9WybOmY9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:O94874	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-1048088|intact:EBI-2798769|uniprotkb:Q8N765|uniprotkb:Q9NTQ0|uniprotkb:A0PJ53|uniprotkb:B4DJ57|uniprotkb:C0H5X5|ensembl:ENSP00000358283.4	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:ufl1_human(display_long)|uniprotkb:UFL1(gene name)|psi-mi:UFL1(display_short)|uniprotkb:E3 UFM1-protein transferase 1(gene name synonym)|uniprotkb:KIAA0776(gene name synonym)|uniprotkb:Novel LZAP-binding protein(gene name synonym)|uniprotkb:RCAD(gene name synonym)|uniprotkb:Regulator of C53/LZAP and DDRGK1(gene name synonym)|uniprotkb:NLBP(gene name synonym)|uniprotkb:MAXER(gene name synonym)|uniprotkb:Multiple alpha-helix protein located at ER(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_056138.1|ensembl:ENSG00000014123.10(gene)|ensembl:ENST00000369278.5(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0002841""(negative regulation of T cell mediated immune response to tumor cell)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006974""(DNA damage response)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032434""(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033146""(regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035861""(site of double-strand break)|go:""GO:0043005""(neuron projection)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050821""(protein stabilization)|go:""GO:0050868""(negative regulation of T cell activation)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0061666""(UFM1 ligase activity)|go:""GO:0061709""(reticulophagy)|go:""GO:0071568""(UFM1 transferase activity)|go:""GO:0071569""(protein ufmylation)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0140501""(positive regulation of reticulophagy)|go:""GO:1902065""(response to L-glutamate)|go:""GO:1903052""(positive regulation of proteolysis involved in protein catabolic process)|go:""GO:1903895""(negative regulation of IRE1-mediated unfolded protein response)|go:""GO:1990592""(protein K69-linked ufmylation)|interpro:IPR018611|mint:O94874|rcsb pdb:8B9X|rcsb pdb:8C0D|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8OJ8|rcsb pdb:8QFC|rcsb pdb:8QFD|reactome:R-HSA-983168|panther:PTHR31057(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:wiJotyDNle7GoYzFkOif0TFNr2w9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9BRR6	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-723761|uniprotkb:Q49AU7|uniprotkb:Q8NBI1|uniprotkb:Q8WZ90|uniprotkb:Q96NF8|uniprotkb:Q9H0A7|ensembl:ENSP00000397694.3	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:adpgk_human(display_long)|uniprotkb:RbBP-35(gene name synonym)|uniprotkb:ADPGK(gene name)|psi-mi:ADPGK(display_short)|uniprotkb:PSEC0260(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_112574.3|refseq:XP_006720775.1|ensembl:ENSG00000159322.18(gene)|ensembl:ENST00000456471.3(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0043843""(ADP-specific glucokinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0061620""(glycolytic process through glucose-6-phosphate)|interpro:IPR007666(ADP-specific phosphofructokinase/glucokinase)|interpro:IPR029056|mint:Q9BRR6|reactome:R-HSA-70171|panther:PTHR21208(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:jeRKymflPO3JABiI6J42cZZEbwc9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q96AG4	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|uniprotkb:B2RE83|ensembl:ENSP00000225972.7	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_060979.2|ensembl:ENSG00000108829.10(gene)|ensembl:ENST00000225972.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045296""(cadherin binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050216|mint:Q96AG4|panther:PTHR45752(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9BQT9	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-11291074|uniprotkb:A0A3B3IRF8|uniprotkb:D3DUT6|uniprotkb:O94831|uniprotkb:Q2T9J5|uniprotkb:Q5UE57|ensembl:ENSP00000266546.6|ensembl:ENSP00000500510.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:cstn3_human(display_long)|uniprotkb:CLSTN3(gene name)|psi-mi:CLSTN3(display_short)|uniprotkb:CS3(gene name synonym)|uniprotkb:KIAA0726(gene name synonym)|uniprotkb:Alcadein-beta(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_055533.2|refseq:XP_006719226.1|ensembl:ENSG00000139182.15(gene)|ensembl:ENSG00000288427.1(gene)|ensembl:ENST00000266546.11(transcript)|ensembl:ENST00000672495.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007416""(synapse assembly)|go:""GO:0009306""(protein secretion)|go:""GO:0009986""(cell surface)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0019852""(L-ascorbic acid metabolic process)|go:""GO:0030425""(dendrite)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035249""(synaptic transmission, glutamatergic)|go:""GO:0042043""(neurexin family protein binding)|go:""GO:0044232""(organelle membrane contact site)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0050806""(positive regulation of synaptic transmission)|go:""GO:0050996""(positive regulation of lipid catabolic process)|go:""GO:0051932""(synaptic transmission, GABAergic)|go:""GO:0051963""(regulation of synapse assembly)|go:""GO:0051965""(positive regulation of synapse assembly)|go:""GO:0097490""(sympathetic neuron projection extension)|go:""GO:0098632""(cell-cell adhesion mediator activity)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0106106""(cold-induced thermogenesis)|go:""GO:0160078""(negative regulation of lipid droplet fusion)|go:""GO:1902474""(positive regulation of protein localization to synapse)|go:""GO:1904861""(excitatory synapse assembly)|go:""GO:1904862""(inhibitory synapse assembly)|go:""GO:1904889""(regulation of excitatory synapse assembly)|go:""GO:1904890""(negative regulation of excitatory synapse assembly)|go:""GO:1905606""(regulation of presynapse assembly)|go:""GO:1905704""(positive regulation of inhibitory synapse assembly)|go:""GO:1990845""(adaptive thermogenesis)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR045588|mint:Q9BQT9|panther:PTHR14139(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:6rGsIDkSoXvlLtfjgJ/dp0TEPU89606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q5SWA1	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-2815482|uniprotkb:Q53GQ4|uniprotkb:Q96SN1|uniprotkb:Q6P156|uniprotkb:Q658M2|ensembl:ENSP00000356156.4	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:pr15b_human(display_long)|uniprotkb:PPP1R15B(gene name)|psi-mi:PPP1R15B(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000158615.10(gene)|ensembl:ENST00000367188.5(transcript)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006417""(regulation of translation)|go:""GO:0006983""(ER overload response)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|interpro:IPR019512|interpro:IPR019523|interpro:IPR051254|mint:Q5SWA1|rcsb pdb:4V0U|rcsb pdb:4V0V|rcsb pdb:4V0W|rcsb pdb:4V0X|refseq:NP_116222.4|efo:""Orphanet:391408""|panther:PTHR16489(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:O44pxO1/HwzW+jWPV5GVBizBlCQ9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q13190	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|uniprotkb:F8W8Q9|ensembl:ENSP00000294179.3	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_003155.2|refseq:NP_001231595.1|ensembl:ENSG00000162236.13(gene)|ensembl:ENST00000294179.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0006906""(vesicle fusion)|go:""GO:0012505""(endomembrane system)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0031201""(SNARE complex)|go:""GO:0031982""(vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0045296""(cadherin binding)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048278""(vesicle docking)|go:""GO:0048280""(vesicle fusion with Golgi apparatus)|go:""GO:0090166""(Golgi disassembly)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|interpro:IPR045242|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001317223.1|dip:DIP-56987N|panther:PTHR19957(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q9BWL3	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-16771163|ensembl:ENSP00000357507.4|uniprotkb:A8K3G8|uniprotkb:D3DV72|uniprotkb:D3DV74|uniprotkb:Q5M801|uniprotkb:Q5VU73|uniprotkb:Q5VU83|uniprotkb:Q96HP7|uniprotkb:Q9UFU2|uniprotkb:Q9UGL7|uniprotkb:Q9UGL8|uniprotkb:Q9Y2R6	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:ca043_human(display_long)|uniprotkb:C1orf43(gene name)|psi-mi:C1orf43(display_short)|uniprotkb:NICE3(gene name synonym)|uniprotkb:NS5ATP4(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 4(gene name synonym)|uniprotkb:Protein NICE-3(gene name synonym)|uniprotkb:S863-3(gene name synonym)|uniprotkb:HSPC012(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000143612.21(gene)|ensembl:ENST00000368521.10(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005739""(mitochondrion)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006909""(phagocytosis)|go:""GO:0016020""(membrane)|interpro:IPR010876(NICE-3)|mint:Q9BWL3|refseq:NP_001092086.1|refseq:NP_001284646.1|refseq:NP_001284647.1|refseq:NP_001284649.1|refseq:NP_001284650.1|refseq:NP_001284652.1|refseq:NP_056264.1|refseq:NP_620077.1|panther:PTHR21425(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:L5dPZ3YNGbmbzVR0nb+Gjzz5H5s9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:P63000	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-413628|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q9BTB4|uniprotkb:Q5JAA8|ensembl:ENSP00000258737.7	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303808|imex:IM-27647-93	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"efo:""Orphanet:500159""|ensembl:ENSG00000136238.20(gene)|ensembl:ENST00000348035.9(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003376""(sphingosine-1-phosphate receptor signaling pathway)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006954""(inflammatory response)|go:""GO:0007015""(actin filament organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009611""(response to wounding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031529""(ruffle organization)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032707""(negative regulation of interleukin-23 production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042470""(melanosome)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0043197""(dendritic spine)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045428""(regulation of nitric oxide biosynthetic process)|go:""GO:0045730""(respiratory burst)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048870""(cell motility)|go:""GO:0051022""(Rho GDP-dissociation inhibitor binding)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051668""(localization within membrane)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060263""(regulation of respiratory burst)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0097178""(ruffle assembly)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902622""(regulation of neutrophil migration)|go:""GO:1903348""(positive regulation of bicellular tight junction assembly)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:7DPA|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|rcsb pdb:7SJ4|rcsb pdb:7USD|rcsb pdb:7USE|rcsb pdb:8I5V|rcsb pdb:8I5W|rcsb pdb:8Q0N|rcsb pdb:8WEJ|rcsb pdb:8ZJ2|rcsb pdb:8ZJI|rcsb pdb:8ZJJ|rcsb pdb:8ZJK|rcsb pdb:8ZJL|rcsb pdb:8ZJM|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-9748787|reactome:R-HSA-983231|refseq:NP_008839.2|refseq:NP_061485.1|dip:DIP-29260N|panther:PTHR24072(orthology-group)|ensembl:ENSP00000258737.7|ensembl:ENST00000356142.4|ensembl:ENSP00000348461.4"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:B976E35E945C4996|rigid:Wki7DHaB2dC8TymeIjAPR7gq7rk	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:P02461	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-2431491|uniprotkb:P78429|uniprotkb:Q15112|uniprotkb:Q9UC90|uniprotkb:Q9UC91|uniprotkb:Q16403|uniprotkb:Q53S91|uniprotkb:Q541P8|uniprotkb:Q6LDB3|uniprotkb:Q6LDJ2|uniprotkb:Q6LDJ3|uniprotkb:Q7KZ56|uniprotkb:Q8N6U4|uniprotkb:Q9UC88|uniprotkb:Q9UC89|uniprotkb:D2JYH5|uniprotkb:R4N3C5|uniprotkb:V9GZI1|uniprotkb:D3DPH4|ensembl:ENSP00000304408.4	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:co3a1_human(display_long)|uniprotkb:COL3A1(gene name)|psi-mi:COL3A1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303864|imex:IM-27647-77	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"ensembl:ENSG00000168542.18(gene)|ensembl:ENST00000304636.9(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001764""(neuron migration)|go:""GO:0001894""(tissue homeostasis)|go:""GO:0002020""(protease binding)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005586""(collagen type III trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007507""(heart development)|go:""GO:0009314""(response to radiation)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0021819""(layer formation in cerebral cortex)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030168""(platelet activation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0030324""(lung development)|go:""GO:0032905""(transforming growth factor beta1 production)|go:""GO:0034097""(response to cytokine)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0036022""(limb joint morphogenesis)|go:""GO:0042060""(wound healing)|go:""GO:0043588""(skin development)|go:""GO:0046332""(SMAD binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048565""(digestive tract development)|go:""GO:0050777""(negative regulation of immune response)|go:""GO:0060350""(endochondral bone morphogenesis)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0097435""(supramolecular fiber organization)|go:""GO:1990776""(response to angiotensin)|go:""GO:2001223""(negative regulation of neuron migration)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|mint:P02461|rcsb pdb:2V53|rcsb pdb:3DMW|rcsb pdb:4AE2|rcsb pdb:4AEJ|rcsb pdb:4AK3|rcsb pdb:4GYX|rcsb pdb:6FZV|rcsb pdb:6FZW|rcsb pdb:7WWR|rcsb pdb:7WWS|rcsb pdb:7XAN|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_000081.1|dip:DIP-57177N|efo:""Orphanet:231160""|efo:""Orphanet:2500""|efo:""Orphanet:286""|efo:""Orphanet:636941""|efo:""Orphanet:86""|panther:PTHR24023(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:mJwvNKDtUVF6OMwaeEO2xcjKYWE9606	intact-crc:CA8EBE754A6F7A2A|rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA	false	binding-associated region:1-26|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:P17655	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-1028956|uniprotkb:Q16738|uniprotkb:Q6PJT3|uniprotkb:Q8WU26|uniprotkb:Q9HBB1|uniprotkb:A6NDG7|ensembl:ENSP00000295006.5|uniprotkb:B7ZA96|uniprotkb:E7ES58	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:can2_human(display_long)|uniprotkb:CAPN2(gene name)|psi-mi:CAPN2(display_short)|uniprotkb:CANPL2(gene name synonym)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym)|uniprotkb:Calpain large polypeptide L2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303864|imex:IM-27647-77	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"refseq:NP_001139540.1|refseq:NP_001739.2|ensembl:ENSG00000162909.18(gene)|ensembl:ENST00000295006.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001824""(blastocyst development)|go:""GO:0004198""(calcium-dependent cysteine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006508""(proteolysis)|go:""GO:0007520""(myoblast fusion)|go:""GO:0007565""(female pregnancy)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0019899""(enzyme binding)|go:""GO:0030425""(dendrite)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031143""(pseudopodium)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0048266""(behavioral response to pain)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0110158""(calpain complex)|go:""GO:0140249""(protein catabolic process at postsynapse)|go:""GO:1901741""(positive regulation of myoblast fusion)|go:""GO:2001247""(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR042736|mint:P17655|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:2NQA|reactome:R-HSA-1474228|reactome:R-HSA-8862803|reactome:R-HSA-9856530|reactome:R-HSA-9860927|panther:PTHR10183(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:r60XX66kihGVLaa9888soeXjc0M9606	intact-crc:CA8EBE754A6F7A2A|rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA	false	binding-associated region:1-26|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:O75439	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-721199|uniprotkb:O60416|uniprotkb:Q96FV4|ensembl:ENSP00000249269.4	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:mppb_human(display_long)|uniprotkb:Beta-MPP(gene name synonym)|uniprotkb:P-52(gene name synonym)|uniprotkb:PMPCB(gene name)|psi-mi:PMPCB(display_short)|uniprotkb:MPPB(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303864|imex:IM-27647-77	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"efo:""Orphanet:569290""|ensembl:ENSG00000105819.15(gene)|ensembl:ENST00000249269.9(transcript)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006627""(protein processing involved in protein targeting to mitochondrion)|go:""GO:0006851""(mitochondrial calcium ion transmembrane transport)|go:""GO:0017087""(mitochondrial processing peptidase complex)|go:""GO:0046872""(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR050361|mint:O75439|reactome:R-HSA-1268020|reactome:R-HSA-8949664|refseq:NP_004270.2|panther:PTHR11851(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:TMqHDYssMbBpUdw0HcGrMPaJd/89606	intact-crc:CA8EBE754A6F7A2A|rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA	false	binding-associated region:1-26|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:P04632	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-711828|ensembl:ENSP00000246533.2|ensembl:ENSP00000464849.1|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303864|imex:IM-27647-77	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"ensembl:ENSG00000126247.11(gene)|ensembl:ENST00000246533.8(transcript)|ensembl:ENST00000588815.5(transcript)|go:""GO:0004198""(calcium-dependent cysteine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0110158""(calpain complex)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:XP_005259352.1|refseq:XP_005259353.1|refseq:NP_001289561.1|refseq:NP_001289562.1|panther:PTHR46735(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606	intact-crc:CA8EBE754A6F7A2A|rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA	false	binding-associated region:1-26|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:Q06203	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-3920254|ensembl:ENSP00000264220.2	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:pur1_human(display_long)|uniprotkb:PPAT(gene name)|psi-mi:PPAT(display_short)|uniprotkb:GPAT(gene name synonym)|uniprotkb:Glutamine phosphoribosylpyrophosphate amidotransferase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303864|imex:IM-27647-77	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"refseq:NP_002694.3|ensembl:ENSG00000128059.8(gene)|ensembl:ENST00000264220.6(transcript)|go:""GO:0004044""(amidophosphoribosyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006177""(GMP biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0044208""('de novo' AMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0097294""('de novo' XMP biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005854(Amidophosphoribosyl transferase)|interpro:IPR017932|interpro:IPR029055|interpro:IPR029057|interpro:IPR035584|mint:Q06203|reactome:R-HSA-73817|panther:PTHR11907(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:W+6JIL0Nlil+ZMhxjlmySnQkqZE9606	intact-crc:CA8EBE754A6F7A2A|rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA	false	binding-associated region:1-26|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:P54819	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-1056291|uniprotkb:Q16856|uniprotkb:Q5TIF7|uniprotkb:Q8TCY2|uniprotkb:Q8TCY3|uniprotkb:A8K6L1|uniprotkb:B4DHH7|uniprotkb:B4DL64|uniprotkb:Q5EB54|ensembl:ENSP00000499935.1	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	"psi-mi:kad2_human(display_long)|uniprotkb:AK2(gene name)|psi-mi:AK2(display_short)|uniprotkb:ADK2(gene name synonym)|uniprotkb:ATP-AMP transphosphorylase 2(gene name synonym)|uniprotkb:""ATP:AMP phosphotransferase""(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303864|imex:IM-27647-77	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"ensembl:ENSG00000004455.18(gene)|ensembl:ENST00000672715.1(transcript)|go:""GO:0004017""(adenylate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006172""(ADP biosynthetic process)|go:""GO:0015949""(nucleobase-containing small molecule interconversion)|go:""GO:0046033""(AMP metabolic process)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097226""(sperm mitochondrial sheath)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028587|interpro:IPR033690|mint:P54819|rcsb pdb:2C9Y|reactome:R-HSA-499943|refseq:NP_001186128.1|refseq:NP_001306068.1|refseq:NP_001306069.1|refseq:NP_001616.1|refseq:NP_037543.1|efo:""Orphanet:33355""|panther:PTHR23359(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:pzIKBBzoytYPw3r87WMBueRNpWw9606	intact-crc:CA8EBE754A6F7A2A|rigid:jCo/N8JOLDjkpDcKjNyDWduI9MA	false	binding-associated region:1-26|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:Q29RF7	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427.8	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303877|imex:IM-27647-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|panther:PTHR12663(orthology-group)|refseq:XP_016863417.1|dip:DIP-35419N|ensembl:ENSG00000121892.15(gene)|ensembl:ENST00000303538.13(transcript)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0008156""(negative regulation of DNA replication)|go:""GO:0051301""(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606	intact-crc:1EC20BC95CB17018|rigid:5niHQcpdaa2bLMOe/kbhzktOnvg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:Q9NQC3	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-715945|intact:EBI-1753019|uniprotkb:Q9Y2Y7|uniprotkb:O94962|uniprotkb:Q9BXG5|uniprotkb:Q9H212|uniprotkb:Q9H3I3|uniprotkb:Q9UQ42|uniprotkb:Q9Y293|uniprotkb:Q9Y5U6|intact:EBI-1958210|intact:EBI-1056082|uniprotkb:Q7L7Q8|uniprotkb:Q96B16|intact:EBI-28967519|uniprotkb:Q7L7Q5|uniprotkb:Q7L7Q6|uniprotkb:Q8IUA4|ensembl:ENSP00000337838.6	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:rtn4_human(display_long)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303877|imex:IM-27647-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"refseq:XP_005264491.1|refseq:XP_016860007.1|refseq:XP_016860008.1|dip:DIP-42003N|ensembl:ENSG00000115310.19(gene)|ensembl:ENST00000337526.11(transcript)|go:""GO:0001825""(blastocyst formation)|go:""GO:0002523""(leukocyte migration involved in inflammatory response)|go:""GO:0003723""(RNA binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007413""(axonal fasciculation)|go:""GO:0007420""(brain development)|go:""GO:0010634""(positive regulation of epithelial cell migration)|go:""GO:0014069""(postsynaptic density)|go:""GO:0021801""(cerebral cortex radial glia-guided migration)|go:""GO:0022009""(central nervous system vasculogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030517""(negative regulation of axon extension)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0033601""(positive regulation of mammary gland epithelial cell proliferation)|go:""GO:0034165""(positive regulation of toll-like receptor 9 signaling pathway)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0035441""(cell migration involved in vasculogenesis)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050821""(protein stabilization)|go:""GO:0051292""(nuclear pore complex assembly)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0061462""(protein localization to lysosome)|go:""GO:0070161""(anchoring junction)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071782""(endoplasmic reticulum tubular network)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|go:""GO:0071787""(endoplasmic reticulum tubular network formation)|go:""GO:0090156""(intracellular sphingolipid homeostasis)|go:""GO:0098826""(endoplasmic reticulum tubular network membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0120078""(cell adhesion involved in sprouting angiogenesis)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902430""(negative regulation of amyloid-beta formation)|go:""GO:1902624""(positive regulation of neutrophil migration)|go:""GO:1905523""(positive regulation of macrophage migration)|go:""GO:1905552""(positive regulation of protein localization to endoplasmic reticulum)|go:""GO:1905580""(positive regulation of ERBB3 signaling pathway)|go:""GO:1905653""(positive regulation of artery morphogenesis)|go:""GO:1990809""(endoplasmic reticulum tubular network membrane organization)|go:""GO:2000172""(regulation of branching morphogenesis of a nerve)|go:""GO:2000347""(positive regulation of hepatocyte proliferation)|go:""GO:2001213""(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|interpro:IPR046964|mint:Q9NQC3|rcsb pdb:2G31|rcsb pdb:2JV5|reactome:R-HSA-193634|refseq:NP_001308788.1|refseq:NP_001308789.1|refseq:NP_001308790.1|refseq:NP_001308791.1|refseq:NP_001308792.1|refseq:NP_001308833.1|refseq:NP_008939.1|refseq:NP_065393.1|refseq:NP_722550.1|refseq:NP_997403.1|refseq:NP_997404.1|panther:PTHR45799(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:uhivTNOPdC7+q81CliY0Ozu0EwA9606	intact-crc:1EC20BC95CB17018|rigid:5niHQcpdaa2bLMOe/kbhzktOnvg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:Q9UIA9	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512.9	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303877|imex:IM-27647-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"refseq:NP_055839.3|ensembl:ENSG00000130227.17(gene)|ensembl:ENST00000252512.14(transcript)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0031267""(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|mint:Q9UIA9|panther:PTHR12596(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606	intact-crc:1EC20BC95CB17018|rigid:5niHQcpdaa2bLMOe/kbhzktOnvg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:Q9BSJ2	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936.3|ensembl:ENSP00000506731.1|ensembl:ENSP00000507482.1|ensembl:ENSP00000507610.1|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303877|imex:IM-27647-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"ensembl:ENSG00000130640.15(gene)|ensembl:ENST00000252936.8(transcript)|ensembl:ENST00000682123.1(transcript)|ensembl:ENST00000682515.1(transcript)|ensembl:ENST00000683612.1(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000922""(spindle pole)|go:""GO:0000930""(gamma-tubulin complex)|go:""GO:0001764""(neuron migration)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007420""(brain development)|go:""GO:0016020""(membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|rcsb pdb:7QJ0|rcsb pdb:7QJ1|rcsb pdb:7QJ2|rcsb pdb:7QJ3|rcsb pdb:7QJ4|rcsb pdb:7QJ5|rcsb pdb:7QJ6|rcsb pdb:7QJ7|rcsb pdb:7QJ8|rcsb pdb:7QJ9|rcsb pdb:7QJA|rcsb pdb:7QJB|rcsb pdb:7QJC|rcsb pdb:7QJD|rcsb pdb:8Q62|rcsb pdb:8RX1|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|reactome:R-HSA-380270|reactome:R-HSA-380320|refseq:NP_006650.1|refseq:NP_001243547.1|refseq:NP_001243546.1|panther:PTHR19302(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606	intact-crc:1EC20BC95CB17018|rigid:5niHQcpdaa2bLMOe/kbhzktOnvg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:Q15058	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-1045252|uniprotkb:Q14CI8|uniprotkb:Q4G0A5|uniprotkb:Q5T1W3|ensembl:ENSP00000356319.4|ensembl:ENSP00000483069.1	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:kif14_human(display_long)|uniprotkb:KIF14(gene name)|psi-mi:KIF14(display_short)|uniprotkb:KIAA0042(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303877|imex:IM-27647-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"efo:""Orphanet:2512""|efo:""Orphanet:439897""|ensembl:ENSG00000118193.12(gene)|ensembl:ENST00000367350.5(transcript)|ensembl:ENST00000614960.4(transcript)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0003777""(microtubule motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0008017""(microtubule binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0010389""(regulation of G2/M transition of mitotic cell cycle)|go:""GO:0015631""(tubulin binding)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021685""(cerebellar granular layer structural organization)|go:""GO:0021693""(cerebellar Purkinje cell layer structural organization)|go:""GO:0021695""(cerebellar cortex development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021772""(olfactory bulb development)|go:""GO:0021846""(cell proliferation in forebrain)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0031146""(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0031641""(regulation of myelination)|go:""GO:0032147""(activation of protein kinase activity)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032487""(regulation of Rap protein signal transduction)|go:""GO:0033624""(negative regulation of integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043523""(regulation of neuron apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0051233""(spindle midzone)|go:""GO:0051301""(cell division)|go:""GO:0090543""(Flemming body)|go:""GO:1903429""(regulation of cell maturation)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR027417|interpro:IPR032405|interpro:IPR036961|mint:Q15058|reactome:R-HSA-5625900|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001292721.1|refseq:NP_055690.1|refseq:XP_011508533.1|refseq:XP_011508534.1|refseq:XP_016858494.1|panther:PTHR24115(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:xIx+ywoBoaILDgAkmzxHOtF15DA9606	intact-crc:1EC20BC95CB17018|rigid:5niHQcpdaa2bLMOe/kbhzktOnvg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI5	uniprotkb:Q96KR6	intact:EBI-22303849|uniprotkb:O84119|uniprotkb:Q9RPP9	intact:EBI-18938272|ensembl:ENSP00000360437.3|uniprotkb:B2RBQ9|uniprotkb:E1P5Y7|uniprotkb:Q8WVN2|uniprotkb:Q9BYL6|uniprotkb:Q9H418	psi-mi:incf_chltr(display_long)|uniprotkb:incF(gene name)|psi-mi:incF(display_short)|uniprotkb:CT_117(locus name)	psi-mi:f210b_human(display_long)|uniprotkb:FAM210B(gene name)|psi-mi:FAM210B(display_short)|uniprotkb:C20orf108(gene name synonym)|uniprotkb:PSEC0265(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303877|imex:IM-27647-17	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219620.1|refseq:WP_010725072.1|interpro:IPR035119|mint:P0DJI5"	"ensembl:ENSG00000124098.10(gene)|ensembl:ENST00000371384.4(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0016020""(membrane)|go:""GO:0043249""(erythrocyte maturation)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0071392""(cellular response to estradiol stimulus)|interpro:IPR009688(Protein of unknown function DUF1279)|interpro:IPR045866|mint:Q96KR6|refseq:NP_543011.2|panther:PTHR21377(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/02/27	rogid:C6DuaOtU7uXwpB/eZ9UrX4CSqIY272561	rogid:UMQqeHBUt+7hAYbTA131Zkr/mxY9606	intact-crc:1EC20BC95CB17018|rigid:5niHQcpdaa2bLMOe/kbhzktOnvg	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DPS6	uniprotkb:Q9NX20	intact:EBI-22303890|uniprotkb:O84120|uniprotkb:Q9RPP8	intact:EBI-2560190|ensembl:ENSP00000300151.4|uniprotkb:Q9HB70|uniprotkb:Q9BYD0	psi-mi:incg_chltr(display_long)|uniprotkb:incG(gene name)|psi-mi:incG(display_short)|uniprotkb:CT_118(locus name)	psi-mi:rm16_human(display_long)|uniprotkb:MRPL16(gene name)|psi-mi:MRPL16(display_short)|uniprotkb:39S ribosomal protein L16, mitochondrial(gene name synonym)|uniprotkb:PNAS-111(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303904|imex:IM-27647-33	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219621.1|refseq:WP_009871465.1|mint:P0DPS6"	"refseq:NP_060310.1|ensembl:ENSG00000166902.5(gene)|ensembl:ENST00000300151.5(transcript)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005762""(mitochondrial large ribosomal subunit)|go:""GO:0019843""(rRNA binding)|go:""GO:0032543""(mitochondrial translation)|interpro:IPR000114(Ribosomal protein L16)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR036920|interpro:IPR047873|mint:Q9NX20|rcsb pdb:3IY9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:7OI6|rcsb pdb:7OI7|rcsb pdb:7OI8|rcsb pdb:7OI9|rcsb pdb:7OIA|rcsb pdb:7OIB|rcsb pdb:7OIC|rcsb pdb:7OID|rcsb pdb:7OIE|rcsb pdb:7PD3|rcsb pdb:7PO4|rcsb pdb:7QH6|rcsb pdb:7QH7|rcsb pdb:7QI4|rcsb pdb:7QI5|rcsb pdb:7QI6|rcsb pdb:8ANY|rcsb pdb:8K2A|rcsb pdb:8K2B|rcsb pdb:8OIR|rcsb pdb:8OIT|rcsb pdb:8PK0|rcsb pdb:8QSJ|rcsb pdb:8QU1|rcsb pdb:8QU5|rcsb pdb:8XT0|rcsb pdb:8XT1|rcsb pdb:8XT2|rcsb pdb:8XT3|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|panther:PTHR12220(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:OcJqgIA74MSkXHwVH+wFDDj5T70272561	rogid:5ngQm8RUtN0SGgxJN2mGtWKhHMU9606	intact-crc:0A17A86E94640C1C|rigid:J9X92Yadt9aUVtd50HrxnixVMlA	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:P01111	intact:EBI-22303910	intact:EBI-721993|uniprotkb:Q14971|uniprotkb:Q15104|uniprotkb:Q15282|ensembl:ENSP00000358548.4	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	psi-mi:rasn_human(display_long)|uniprotkb:Transforming protein N-Ras(gene name synonym)|uniprotkb:NRAS(gene name)|psi-mi:NRAS(display_short)|uniprotkb:HRAS1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"efo:""Orphanet:146""|efo:""Orphanet:2612""|efo:""Orphanet:268114""|efo:""Orphanet:389""|efo:""Orphanet:626""|efo:""Orphanet:648""|efo:""Orphanet:86834""|ensembl:ENSG00000213281.5(gene)|ensembl:ENST00000369535.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0019003""(GDP binding)|go:""GO:0044877""(protein-containing complex binding)|rcsb pdb:6MPP|go:""GO:0045445""(myoblast differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01111|rcsb pdb:2N9C|rcsb pdb:3CON|rcsb pdb:5UHV|rcsb pdb:6E6H|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6WGH|rcsb pdb:6ZIO|rcsb pdb:6ZIR|rcsb pdb:6ZIZ|rcsb pdb:7F68|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7PB2|rcsb pdb:8TBI|rcsb pdb:8VM2|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5658442|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9753510|reactome:R-HSA-9753512|refseq:NP_002515.1|dip:DIP-1058N|panther:PTHR24070(orthology-group)|ensembl:ENSP00000358548.4"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:Et90BD+t6LnYThbW6ShQge1GRK89606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:O43504	intact:EBI-22303910	intact:EBI-713382|uniprotkb:Q6IBD8|ensembl:ENSP00000473439.1|intact:EBI-10173304|uniprotkb:A0A0C4DGV4	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	psi-mi:ltor5_human(display_long)|uniprotkb:LAMTOR5(gene name)|psi-mi:LAMTOR5(display_short)|uniprotkb:HBXIP(gene name synonym)|uniprotkb:Hepatitis B virus X-interacting protein(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5(gene name synonym)|uniprotkb:XIP(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"refseq:NP_006393.2|ensembl:ENSG00000134248.14(gene)|ensembl:ENST00000602318.6(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009615""(response to virus)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0019079""(viral genome replication)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0061462""(protein localization to lysosome)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071986""(Ragulator complex)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1905636""(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:""GO:1990877""(FNIP-folliculin RagC/D GAP)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR024135|mint:O43504|rcsb pdb:3MS6|rcsb pdb:3MSH|rcsb pdb:5VOK|rcsb pdb:5X6U|rcsb pdb:5X6V|rcsb pdb:5Y38|rcsb pdb:5Y39|rcsb pdb:5Y3A|rcsb pdb:5YK3|rcsb pdb:5YK5|rcsb pdb:6B9X|rcsb pdb:6EHP|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6U62|rcsb pdb:6ULG|rcsb pdb:6WJ2|rcsb pdb:6WJ3|rcsb pdb:7T3A|rcsb pdb:7T3B|rcsb pdb:7T3C|rcsb pdb:7UX2|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8DHB|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288|dip:DIP-61482N|panther:PTHR13342(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:p4hO3N/2WyUvZJzDxQVPtjPNdNY9606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:Q9NP73	intact:EBI-22303910	intact:EBI-947892|uniprotkb:B1AKD6|uniprotkb:B1AKM1|uniprotkb:B2R5L5|uniprotkb:B7Z6J0|uniprotkb:B7Z804|uniprotkb:B7Z9A8|uniprotkb:B7ZAJ1|uniprotkb:B7ZB57|uniprotkb:Q9H5U8|uniprotkb:Q5JXY9|uniprotkb:Q17RC3|uniprotkb:B7Z847|ensembl:ENSP00000378260.3	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	psi-mi:alg13_human(display_long)|uniprotkb:ALG13(gene name)|psi-mi:ALG13(display_short)|uniprotkb:CXorf45(gene name synonym)|uniprotkb:Asparagine-linked glycosylation 13 homolog(gene name synonym)|uniprotkb:Glycosyltransferase 28 domain-containing protein 1(gene name synonym)|uniprotkb:MDS031(orf name)|uniprotkb:GLT28D1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"ensembl:ENSG00000101901.13(gene)|ensembl:ENST00000394780.8(transcript)|go:""GO:0004577""(N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0006488""(dolichol-linked oligosaccharide biosynthetic process)|go:""GO:0006508""(proteolysis)|go:""GO:0043541""(UDP-N-acetylglucosamine transferase complex)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|interpro:IPR002999(Tudor)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR007235(Glycosyl transferase, family 28, C-terminal)|interpro:IPR038765|interpro:IPR039042|interpro:IPR047387|mint:Q9NP73|reactome:R-HSA-446193|reactome:R-HSA-5633231|refseq:NP_001034299.3|refseq:NP_001093392.1|refseq:NP_001161857.1|refseq:NP_001244159.1|refseq:NP_001244160.1|refseq:NP_001244163.1|refseq:NP_001244166.1|refseq:NP_001244170.1|refseq:NP_060936.1|efo:""Orphanet:324422""|efo:""Orphanet:777""|panther:PTHR12867(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:IWuKvuIaEYMzcYT6dqoUr/1Uouc9606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:P38606	intact:EBI-22303910	intact:EBI-1054757|intact:EBI-10982175|uniprotkb:Q53YD9|uniprotkb:Q96DY6|uniprotkb:Q9UHY3|uniprotkb:B2RBR8|uniprotkb:D3DN75|uniprotkb:B7Z1R5|ensembl:ENSP00000273398.3|ensembl:ENSP00000515542.1|ensembl:ENSP00000515547.1|ensembl:ENSP00000515548.1	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	psi-mi:vata_human(display_long)|uniprotkb:Vacuolar proton pump subunit alpha(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit(gene name synonym)|uniprotkb:Vacuolar ATPase isoform VA68(gene name synonym)|uniprotkb:ATP6V1A(gene name)|psi-mi:ATP6V1A(display_short)|uniprotkb:ATP6A1(gene name synonym)|uniprotkb:ATP6V1A1(gene name synonym)|uniprotkb:VPP2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"efo:""Orphanet:357074""|efo:""Orphanet:442835""|ensembl:ENSG00000114573.12(gene)|ensembl:ENST00000273398.8(transcript)|ensembl:ENST00000703904.2(transcript)|ensembl:ENST00000703910.1(transcript)|ensembl:ENST00000703911.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000221""(vacuolar proton-transporting V-type ATPase, V1 domain)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016469""(proton-transporting two-sector ATPase complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030141""(secretory granule)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046933""(proton-transporting ATP synthase activity, rotational mechanism)|go:""GO:0046961""(proton-transporting ATPase activity, rotational mechanism)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0051452""(intracellular pH reduction)|go:""GO:0061795""(Golgi lumen acidification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0098850""(extrinsic component of synaptic vesicle membrane)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|interpro:IPR055190|mint:P38606|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|rcsb pdb:7UNF|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-9857377|refseq:NP_001681.2|panther:PTHR43607(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:GqPRFwsl5tDH83kpE8Al7NiYWrI9606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:Q6PIU2	intact:EBI-22303910	intact:EBI-2907902|uniprotkb:B7Z2K4|uniprotkb:B7Z3A1|uniprotkb:B7Z5U2|uniprotkb:B7Z906|uniprotkb:B7ZAW6|uniprotkb:Q86WZ1|uniprotkb:Q9P2I4|uniprotkb:F5H7K4|ensembl:ENSP00000418571.4	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	psi-mi:nceh1_human(display_long)|uniprotkb:NCEH1(gene name)|psi-mi:NCEH1(display_short)|uniprotkb:AADACL1(gene name synonym)|uniprotkb:KIAA1363(gene name synonym)|uniprotkb:Arylacetamide deacetylase-like 1(gene name synonym)|uniprotkb:Acetylalkylglycerol acetylhydrolase(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"refseq:NP_001139748.1|refseq:NP_001139749.1|refseq:NP_001139750.1|refseq:NP_065843.3|ensembl:ENSG00000144959.11(gene)|ensembl:ENST00000475381.7(transcript)|go:""GO:0004771""(sterol ester esterase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0017171""(serine hydrolase activity)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0046485""(ether lipid metabolic process)|go:""GO:0047378""(acetylalkylglycerol acetylhydrolase activity)|interpro:IPR013094(Alpha/beta hydrolase fold-3)|interpro:IPR017157(Arylacetamide deacetylase)|interpro:IPR029058|interpro:IPR033140|interpro:IPR050300|mint:Q6PIU2|reactome:R-HSA-8964038|panther:PTHR23024(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:ja3glDJZYcd7LadzVHDjBN8qncY9606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:Q99706	intact:EBI-22303910	intact:EBI-10294579|uniprotkb:A8W795|uniprotkb:O43534|uniprotkb:P78400|uniprotkb:O14623|uniprotkb:Q99560|uniprotkb:O14621|uniprotkb:Q99561|uniprotkb:O14622|uniprotkb:P78401|uniprotkb:Q9UQJ7|uniprotkb:Q99562|uniprotkb:Q99559|uniprotkb:O14624|uniprotkb:Q8N738|ensembl:ENSP00000477601.1|ensembl:ENSP00000477886.1|ensembl:ENSP00000477887.1|ensembl:ENSP00000478362.1|ensembl:ENSP00000478491.1|ensembl:ENSP00000479179.1|ensembl:ENSP00000480801.1|ensembl:ENSP00000482206.1|ensembl:ENSP00000482383.1|ensembl:ENSP00000482452.1|ensembl:ENSP00000483101.1|ensembl:ENSP00000483782.1|ensembl:ENSP00000484389.1	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	psi-mi:ki2l4_human(display_long)|uniprotkb:KIR2DL4(gene name)|psi-mi:KIR2DL4(display_short)|uniprotkb:CD158 antigen-like family member D(gene name synonym)|uniprotkb:CD158D(gene name synonym)|uniprotkb:G9P(gene name synonym)|uniprotkb:KIR103AS(gene name synonym)|uniprotkb:Killer cell inhibitory receptor 103AS(gene name synonym)|uniprotkb:MHC class I NK cell receptor KIR103AS(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"refseq:NP_002246.5|ensembl:ENSG00000274609.1(gene)|ensembl:ENSG00000274955.4(gene)|ensembl:ENSG00000275317.4(gene)|ensembl:ENSG00000275456.1(gene)|ensembl:ENSG00000276779.1(gene)|ensembl:ENSG00000277362.1(gene)|ensembl:ENSG00000277750.1(gene)|ensembl:ENSG00000277964.1(gene)|ensembl:ENSG00000278074.1(gene)|ensembl:ENSG00000278271.1(gene)|ensembl:ENSG00000278430.4(gene)|ensembl:ENST00000612573.1(transcript)|ensembl:ENST00000612660.4(transcript)|ensembl:ENST00000613053.1(transcript)|ensembl:ENST00000614653.1(transcript)|ensembl:ENST00000615970.1(transcript)|ensembl:ENST00000616354.4(transcript)|ensembl:ENST00000618297.1(transcript)|ensembl:ENST00000618358.1(transcript)|ensembl:ENST00000618567.1(transcript)|ensembl:ENST00000619637.4(transcript)|ensembl:ENST00000619848.1(transcript)|ensembl:ENST00000620484.4(transcript)|ensembl:ENST00000620486.4(transcript)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0002764""(immune response-regulating signaling pathway)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006968""(cellular defense response)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032394""(MHC class Ib receptor activity)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:2000774""(positive regulation of cellular senescence)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050412|mint:Q99706|rcsb pdb:3WYR|reactome:R-HSA-198933|panther:PTHR11738(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:wMAkL8jQLoP5FlMYL6zhLc8kuUI9606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:O14828	intact:EBI-22303910	intact:EBI-4401333|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0|ensembl:ENSP00000307275.3|ensembl:ENSP00000461521.1	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"refseq:NP_005689.2|refseq:NP_443069.1|ensembl:ENSG00000116521.12(gene)|ensembl:ENSG00000263290.5(gene)|ensembl:ENST00000302631.8(transcript)|ensembl:ENST00000570831.5(transcript)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0015031""(protein transport)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|panther:PTHR10687(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:O15162	intact:EBI-22303910	intact:EBI-740019|uniprotkb:B2R8H8|uniprotkb:B4DTE8|ensembl:ENSP00000345494.4	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	"psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:""Ca(2+)-dependent phospholipid scramblase 1""(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:""Mg(2+)-dependent nuclease""(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"refseq:NP_066928.1|refseq:XP_011511206.1|ensembl:ENSG00000188313.13(gene)|ensembl:ENST00000342435.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004518""(nuclease activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006659""(phosphatidylserine biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006953""(acute-phase response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010288""(response to lead ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017121""(plasma membrane phospholipid scrambling)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0032791""(lead ion binding)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045340""(mercury ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051607""(defense response to virus)|go:""GO:0060368""(regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070782""(phosphatidylserine exposure on apoptotic cell surface)|go:""GO:1905820""(positive regulation of chromosome separation)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_011511209.1|refseq:XP_016862118.1|panther:PTHR23248(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:P51572	intact:EBI-22303910	intact:EBI-77683|uniprotkb:Q13836|uniprotkb:Q96CF0|uniprotkb:D3DWV5|uniprotkb:B3KQ79|ensembl:ENSP00000343458.6|ensembl:ENSP00000494052.1|ensembl:ENSP00000499882.1	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	psi-mi:bap31_human(display_long)|uniprotkb:BCAP31(gene name)|psi-mi:BCAP31(display_short)|uniprotkb:BAP31(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:6C6-AG tumor-associated antigen(gene name synonym)|uniprotkb:DXS1357E(gene name synonym)|uniprotkb:Protein CDM(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"panther:PTHR12701(orthology-group)|efo:""Orphanet:369939""|efo:""Orphanet:369942""|ensembl:ENSG00000185825.17(gene)|ensembl:ENST00000345046.12(transcript)|ensembl:ENST00000647529.1(transcript)|ensembl:ENST00000672675.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016020""(membrane)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070973""(protein localization to endoplasmic reticulum exit site)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1904154""(positive regulation of retrograde protein transport, ER to cytosol)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:P51572|rcsb pdb:4JZL|rcsb pdb:4JZP|rcsb pdb:8XWX|reactome:R-HSA-111465|reactome:R-HSA-75153|reactome:R-HSA-8980692|reactome:R-HSA-983170|reactome:R-HSA-9833110|refseq:NP_001132913.1|refseq:NP_001132929.1|refseq:NP_001243376.1|refseq:NP_005736.3"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:m0aN00PLZJDWA/K1vEbla1W9+S89606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:Q96HR9	intact:EBI-22303910	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861.5	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"ensembl:ENSG00000115255.12(gene)|ensembl:ENST00000395479.10(transcript)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0032386""(regulation of intracellular transport)|go:""GO:0050908""(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|refseq:NP_001316485.1|refseq:NP_612402.1|efo:""Orphanet:791""|panther:PTHR12300(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:O84569	uniprotkb:O60831	intact:EBI-22303910	intact:EBI-2506064|uniprotkb:B2RD20|ensembl:ENSP00000451962.2|ensembl:ENSP00000518158.1	psi-mi:o84569_chltr(display_long)|uniprotkb:CT_565(locus name)	psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303917|imex:IM-27647-53	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:NP_220080.1|refseq:WP_009871930.1|mint:O84569"	"refseq:NP_009144.1|ensembl:ENSG00000243279.4(gene)|ensembl:ENSG00000292222.1(gene)|ensembl:ENST00000553851.3(transcript)|ensembl:ENST00000710261.1(transcript)|go:""GO:0010008""(endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0015813""(L-glutamate transmembrane transport)|go:""GO:0016020""(membrane)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|panther:PTHR12859(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/26	rogid:4CNBDC2uQxXLzdp5VLRBerso0aQ272561	rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606	intact-crc:478CDC7C847114C9|rigid:IqK7J0kc0LGz6A+QaVPDGBH3rHA	false	binding-associated region:1-144|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI3	uniprotkb:Q14315	intact:EBI-22303935|uniprotkb:O84117|uniprotkb:Q9RPQ1	intact:EBI-489954|ensembl:ENSP00000327145.8|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88	psi-mi:incd_chltr(display_long)|uniprotkb:incD(gene name)|psi-mi:incD(display_short)|uniprotkb:CT_115(locus name)	psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303950|imex:IM-27647-79	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219618.1|refseq:WP_009871462.1|interpro:IPR035117|mint:P0DJI3"	"ensembl:ENSG00000128591.17(gene)|ensembl:ENST00000325888.13(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0016528""(sarcoplasm)|go:""GO:0030018""(Z disc)|go:""GO:0030506""(ankyrin binding)|go:""GO:0042383""(sarcolemma)|go:""GO:0042802""(identical protein binding)|go:""GO:0043034""(costamere)|go:""GO:0045171""(intercellular bridge)|go:""GO:0045214""(sarcomere organization)|go:""GO:0051015""(actin filament binding)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|rcsb pdb:7OUU|rcsb pdb:7OUV|rcsb pdb:7P0E|rcsb pdb:8PA0|reactome:R-HSA-446353|refseq:NP_001120959.1|refseq:NP_001449.3|efo:""Orphanet:171445""|efo:""Orphanet:63273""|efo:""Orphanet:75249""|dip:DIP-33398N|panther:PTHR38537(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:NtfH41PBF6GvaI2uBjbJOl4Jsic272561	rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606	intact-crc:2903ECE3B5F6A8E9|rigid:fVRhYpL/aEJTZ/fK0GVaHKB2f7s	false	binding-associated region:95-141|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI3	uniprotkb:P33176	intact:EBI-22303935|uniprotkb:O84117|uniprotkb:Q9RPQ1	intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078.4	psi-mi:incd_chltr(display_long)|uniprotkb:incD(gene name)|psi-mi:incD(display_short)|uniprotkb:CT_115(locus name)	psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303950|imex:IM-27647-79	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219618.1|refseq:WP_009871462.1|interpro:IPR035117|mint:P0DJI3"	"refseq:NP_004512.1|ensembl:ENSG00000170759.11(gene)|ensembl:ENST00000302418.5(transcript)|go:""GO:0003777""(microtubule motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007028""(cytoplasm organization)|go:""GO:0007411""(axon guidance)|go:""GO:0008017""(microtubule binding)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031982""(vesicle)|go:""GO:0032230""(positive regulation of synaptic transmission, GABAergic)|go:""GO:0032418""(lysosome localization)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0035617""(stress granule disassembly)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042802""(identical protein binding)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0051642""(centrosome localization)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072383""(plus-end-directed vesicle transport along microtubule)|go:""GO:0098971""(anterograde dendritic transport of neurotransmitter receptor complex)|go:""GO:0098987""(regulation of modification of synapse structure, modulating synaptic transmission)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0160040""(mitocytosis)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990048""(anterograde neuronal dense core vesicle transport)|go:""GO:1990049""(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|rcsb pdb:7RIK|rcsb pdb:8IXA|rcsb pdb:8IXB|rcsb pdb:8IXD|rcsb pdb:8IXE|rcsb pdb:8IXF|rcsb pdb:8IXG|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-9725370|reactome:R-HSA-983189|dip:DIP-29244N|panther:PTHR24115(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:NtfH41PBF6GvaI2uBjbJOl4Jsic272561	rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606	intact-crc:2903ECE3B5F6A8E9|rigid:fVRhYpL/aEJTZ/fK0GVaHKB2f7s	false	binding-associated region:95-141|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI3	uniprotkb:P51784	intact:EBI-22303935|uniprotkb:O84117|uniprotkb:Q9RPQ1	intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348.3	psi-mi:incd_chltr(display_long)|uniprotkb:incD(gene name)|psi-mi:incD(display_short)|uniprotkb:CT_115(locus name)	psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303950|imex:IM-27647-79	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219618.1|refseq:WP_009871462.1|interpro:IPR035117|mint:P0DJI3"	"refseq:NP_004642.2|ensembl:ENSG00000102226.10(gene)|ensembl:ENST00000218348.7(transcript)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0016579""(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|interpro:IPR050185|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|rcsb pdb:8OYP|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:XP_005272731.1|refseq:XP_011542290.1|dip:DIP-27567N|panther:PTHR21646(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/01	rogid:NtfH41PBF6GvaI2uBjbJOl4Jsic272561	rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606	intact-crc:2903ECE3B5F6A8E9|rigid:fVRhYpL/aEJTZ/fK0GVaHKB2f7s	false	binding-associated region:95-141|strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI3	uniprotkb:Q9Y5P4	intact:EBI-22303935|uniprotkb:O84117|uniprotkb:Q9RPQ1	intact:EBI-739994|uniprotkb:Q96Q85|uniprotkb:Q96Q88|uniprotkb:Q9H2S7|uniprotkb:Q9H2S8|uniprotkb:Q53YV1|uniprotkb:Q53YV2|uniprotkb:A8K7S2|uniprotkb:B3KUB7|ensembl:ENSP00000261415.8|ensembl:ENSP00000494110.2|ensembl:ENSP00000495760.1	psi-mi:incd_chltr(display_long)|uniprotkb:incD(gene name)|psi-mi:incD(display_short)|uniprotkb:CT_115(locus name)	psi-mi:cert_human(display_long)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22303961|imex:IM-27647-19	intact-miscore:0.35	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|refseq:NP_219618.1|refseq:WP_009871462.1|interpro:IPR035117|mint:P0DJI3"	"efo:""Orphanet:528084""|ensembl:ENSG00000113163.19(gene)|ensembl:ENST00000261415.12(transcript)|ensembl:ENST00000643780.2(transcript)|ensembl:ENST00000644072.2(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0006936""(muscle contraction)|go:""GO:0006955""(immune response)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007165""(signal transduction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016301""(kinase activity)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035621""(ER to Golgi ceramide transport)|go:""GO:0035627""(ceramide transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0097001""(ceramide binding)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:0120012""(intermembrane sphingolipid transfer)|go:""GO:0120017""(ceramide transfer activity)|go:""GO:1902387""(ceramide 1-phosphate binding)|go:""GO:1902388""(ceramide 1-phosphate transfer activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002913(Lipid-binding START)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023393|interpro:IPR041952|interpro:IPR051213|mint:Q9Y5P4|rcsb pdb:2E3M|rcsb pdb:2E3N|rcsb pdb:2E3O|rcsb pdb:2E3P|rcsb pdb:2E3Q|rcsb pdb:2E3R|rcsb pdb:2E3S|rcsb pdb:2RSG|rcsb pdb:2Z9Y|rcsb pdb:2Z9Z|rcsb pdb:3H3Q|rcsb pdb:3H3R|rcsb pdb:3H3S|rcsb pdb:3H3T|rcsb pdb:4HHV|rcsb pdb:5JJD|rcsb pdb:5ZYG|rcsb pdb:5ZYH|rcsb pdb:5ZYI|rcsb pdb:5ZYJ|rcsb pdb:5ZYK|rcsb pdb:5ZYL|rcsb pdb:5ZYM|rcsb pdb:6IEZ|rcsb pdb:6IF0|rcsb pdb:6J0O|rcsb pdb:6J81|reactome:R-HSA-1660661|refseq:NP_001123577.1|refseq:NP_005704.1|refseq:NP_112729.1|refseq:XP_006714576.1|refseq:XP_016864408.1|panther:PTHR10219(orthology-group)"	-	-	-	figure legend:F1 ST1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2024/11/14	rogid:NtfH41PBF6GvaI2uBjbJOl4Jsic272561	rogid:AohUpOJQHInz8f5bKv9/Xb5K+/Y9606	intact-crc:D5F816DCFA80D4D8|rigid:G71pXxjDJJPuwCHlwYhluW+eybs	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0102""(sequence tag identification)"	"psi-mi:""MI:0102""(sequence tag identification)"
uniprotkb:P0DJI4	uniprotkb:Q13596	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25295488|imex:IM-27647-35	intact-miscore:0.43	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528.15(gene)|ensembl:ENST00000559844.6(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990460""(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|interpro:IPR036871|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|rcsb pdb:8A1G|rcsb pdb:8ABQ|rcsb pdb:8AFZ|dip:DIP-398N|panther:PTHR10555(orthology-group)"	-	-	-	figure legend:f4a f4e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606	intact-crc:02E8959617E368F8|rigid:goeedF/tULz346QqYmty980UmZQ	false	strep tag:c-c|sufficient binding region:101-132	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P0DJI4	uniprotkb:O60749	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831.2|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25295488|imex:IM-27647-35	intact-miscore:0.43	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"ensembl:ENSG00000205302.7(gene)|ensembl:ENST00000379516.7(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990460""(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037918|mint:O60749|reactome:R-HSA-432722|refseq:NP_003091.2|refseq:NP_001265128.1|panther:PTHR10555(orthology-group)"	-	-	-	figure legend:f4a f4e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606	intact-crc:02E8959617E368F8|rigid:goeedF/tULz346QqYmty980UmZQ	false	strep tag:c-c|sufficient binding region:101-132	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P0DJI4	uniprotkb:Q9Y5X3	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-715760|uniprotkb:Q52LC4|uniprotkb:B7ZKN3|uniprotkb:Q9BWP0|uniprotkb:D3DW26|uniprotkb:Q7KZN0|ensembl:ENSP00000366988.3|ensembl:ENSP00000366998.3	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx5_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25295488|imex:IM-27647-35	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_055241.1|refseq:NP_689413.1|ensembl:ENSG00000089006.17(gene)|ensembl:ENST00000377759.9(transcript)|ensembl:ENST00000377768.7(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001891""(phagocytic cup)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006907""(pinocytosis)|go:""GO:0007174""(epidermal growth factor catabolic process)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010314""(phosphatidylinositol-5-phosphate binding)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0034452""(dynactin binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0045776""(negative regulation of blood pressure)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0070685""(macropinocytic cup)|go:""GO:0080025""(phosphatidylinositol-3,5-bisphosphate binding)|go:""GO:0097422""(tubular endosome)|go:""GO:0098559""(cytoplasmic side of early endosome membrane)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|interpro:IPR042135|mint:Q9Y5X3|rcsb pdb:1SYS|rcsb pdb:5TGH|rcsb pdb:5TGI|rcsb pdb:5TGJ|rcsb pdb:5WY2|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6N5Z|rcsb pdb:8A1G|rcsb pdb:8ABQ|rcsb pdb:8AFZ|reactome:R-HSA-432722|panther:PTHR45850(orthology-group)"	-	-	-	figure legend:f4a f4e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:VR2oUxQ4M2bm5zKeHQlao046QL09606	intact-crc:02E8959617E368F8|rigid:goeedF/tULz346QqYmty980UmZQ	false	strep tag:c-c|sufficient binding region:101-132	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P0DJI4	uniprotkb:Q9UNH7	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25295488|imex:IM-27647-35	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	-	-	-	figure legend:f4a f4e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	intact-crc:02E8959617E368F8|rigid:goeedF/tULz346QqYmty980UmZQ	false	strep tag:c-c|sufficient binding region:101-132	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P0DJI4	uniprotkb:Q9UNH7	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25398962|imex:IM-27647-39	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	-	-	-	figure legend:sf4c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	intact-crc:0913AB6D3BA3A72C|rigid:Yfyd0hSpTk0vp6QxTT2jei5zPjg	false	green fluorescent protein tag:c-c|binding-associated region:101-132	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:Q13596	uniprotkb:P0DJI4	intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785.1	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short)	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272561(chltr)|taxid:272561(chltr)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25399045|imex:IM-27647-97	intact-miscore:0.43	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528.15(gene)|ensembl:ENST00000559844.6(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990460""(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|interpro:IPR036871|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|rcsb pdb:8A1G|rcsb pdb:8ABQ|rcsb pdb:8AFZ|dip:DIP-398N|panther:PTHR10555(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	-	-	-	figure legend:f5A sf5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/12/11	2025/02/27	rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	intact-crc:2C6408703E9B5A5F|rigid:++zQa8MUHWr8nGOCytSEDVBE05Y	false	-	-	-	-	"psi-mi:""MI:0707""(anti tag immunostaining)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:Q9UNH7	uniprotkb:P0DJI4	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272561(chltr)|taxid:272561(chltr)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25399063|imex:IM-27647-99	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	-	-	-	figure legend:f5A sf5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/12/11	2025/03/17	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	intact-crc:11D152D6CDF4DAF2|rigid:Wy+bfvkLXGLqC6/EzHLcEoZnLis	false	-	-	-	-	"psi-mi:""MI:0707""(anti tag immunostaining)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:O60749	uniprotkb:P0DJI4	intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831.2|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name)	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272561(chltr)|taxid:272561(chltr)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25399069|imex:IM-27647-105	intact-miscore:0.43	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000205302.7(gene)|ensembl:ENST00000379516.7(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990460""(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR036871|interpro:IPR037918|mint:O60749|reactome:R-HSA-432722|refseq:NP_003091.2|refseq:NP_001265128.1|panther:PTHR10555(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	-	-	-	figure legend:F5A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/12/11	2024/11/14	rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	intact-crc:29F08639F04ED05A|rigid:RzvDLRdyMbl06IH3oRPXp5wGyRI	false	-	-	-	-	"psi-mi:""MI:0707""(anti tag immunostaining)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:P0DJI4	uniprotkb:Q13596	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785.1	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25420698|imex:IM-27647-106	intact-miscore:0.43	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528.15(gene)|ensembl:ENST00000559844.6(transcript)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0072673""(lamellipodium morphogenesis)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990460""(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|interpro:IPR036871|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|rcsb pdb:8A1G|rcsb pdb:8ABQ|rcsb pdb:8AFZ|dip:DIP-398N|panther:PTHR10555(orthology-group)"	-	-	-	"figure legend:sf5b sf5c|agonist:""\""nocodazole (CHEBI:34892)\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606	intact-crc:878B03D0702DA4D6|rigid:PQjFWtLLO9dNhWl9Pl/yEiBYflw	false	-	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:P0DJI4	uniprotkb:Q9UNH7	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	"psi-mi:""MI:0663""(confocal microscopy)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25420698|imex:IM-27647-106	intact-miscore:0.61	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	-	-	-	"figure legend:sf5b sf5c|agonist:""\""nocodazole (CHEBI:34892)\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	intact-crc:878B03D0702DA4D6|rigid:PQjFWtLLO9dNhWl9Pl/yEiBYflw	false	-	-	-	-	"psi-mi:""MI:0867""(tag visualisation by fluorescence)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:Q9UNH7	uniprotkb:B0B9M4	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	intact:EBI-25421041|uniprotkb:O84118|uniprotkb:Q9RPQ0	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	psi-mi:ince_chlt2(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CTL0371(locus name)	"psi-mi:""MI:0663""(confocal microscopy)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:471472(chlt2)|taxid:471472(""Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25421035|imex:IM-27647-108	intact-miscore:0.27	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	"refseq:WP_009873571.1|refseq:YP_001654455.1|interpro:IPR035118|go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|mint:B0B9M4"	-	-	-	"figure legend:f6d f6e|comment:""\""We also observed increased SNX6 recruitment and SNX6-positive tubules in C. trachomatis serovar L2 transformed with a vector expressing untagged IncE (pIncE) under control of its native promoter compared to C. trachomatis transformed with empty vector (Figure 6D and 6E).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/12/11	2025/03/17	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	rogid:KeYDCr/BYZ31n0CMgSzemsUUpec471472	intact-crc:D4A852CF7D25AA54|rigid:yB0e2S7kowOd2qGl8eo9dqsvLwM	false	-	-	-	-	"psi-mi:""MI:0707""(anti tag immunostaining)"	"psi-mi:""MI:0707""(anti tag immunostaining)"
uniprotkb:P0DJI4	uniprotkb:Q9UNH7	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	"psi-mi:""MI:0096""(pull down)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25398684|imex:IM-27647-95	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	-	-	-	figure legend:f4f|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	intact-crc:8DCE6AD0CA58375E|rigid:Wy+bfvkLXGLqC6/EzHLcEoZnLis	false	tandem tag:?-?|binding-associated region:101-132|strep tag:c-c	his tag:n-n|binding-associated region:1-181	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:P0DJI4	uniprotkb:Q9UNH7	intact:EBI-22303778|uniprotkb:O84118|uniprotkb:Q9RPQ0	intact:EBI-949294|uniprotkb:Q9Y449|uniprotkb:C0H5W9|ensembl:ENSP00000355217.5	psi-mi:ince_chltr(display_long)|uniprotkb:incE(gene name)|psi-mi:incE(display_short)|uniprotkb:CT_116(locus name)	psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Mirrashidi et al. (2015)	pubmed:26118995|imex:IM-27647	taxid:272561(chltr)|taxid:272561(chltr)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-25398676|imex:IM-27647-55	intact-miscore:0.61	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0033644""(host cell membrane)|go:""GO:0140221""(pathogen-containing vacuole membrane)|rcsb pdb:5TP1|refseq:NP_219619.1|refseq:WP_010725071.1|interpro:IPR035118|mint:P0DJI4"	"refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N|ensembl:ENSG00000129515.20(gene)|ensembl:ENST00000362031.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030904""(retromer complex)|go:""GO:0030905""(retromer, tubulation complex)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034452""(dynactin binding)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0097422""(tubular endosome)|go:""GO:0098842""(postsynaptic early endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|panther:PTHR45850(orthology-group)"	-	-	-	figure legend:f4b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/12/11	2025/03/17	rogid:8jKSDhDOMaGC4M5UzaABfjPPVsQ272561	rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606	intact-crc:1E9F84533065D050|rigid:Wy+bfvkLXGLqC6/EzHLcEoZnLis	false	strep tag:c-c	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B7UM99	uniprotkb:P05783	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Batchelor et al. (2004)	imex:IM-27518|pubmed:14710194	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22229017|imex:IM-27518-3	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	"go:""GO:0016020""(membrane)|go:""GO:0005737""(cytoplasm)"	-	-	figure legend:fig.2a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/25	2025/03/25	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	intact-crc:448083619450CD45|rigid:VfXrurNnW99L71cDN2oN/BJy/Vw	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B7UM99	uniprotkb:P05783	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Batchelor et al. (2004)	imex:IM-27518|pubmed:14710194	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22229023|imex:IM-27518-5	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	"go:""GO:0005737""(cytoplasm)"	-	-	figure legend:fig.2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/25	2025/03/25	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	intact-crc:7403D3D2BC44A78C|rigid:VfXrurNnW99L71cDN2oN/BJy/Vw	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B7UM99	uniprotkb:P05787	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-297852|uniprotkb:Q14099|uniprotkb:Q14716|uniprotkb:Q14717|uniprotkb:Q53GJ0|uniprotkb:Q6DHW5|uniprotkb:Q6GMY0|uniprotkb:Q6P4C7|uniprotkb:Q96J60|uniprotkb:A8K4H3|uniprotkb:B0AZN5|ensembl:ENSP00000293308.6|ensembl:ENSP00000447402.1|ensembl:ENSP00000447566.1|ensembl:ENSP00000509398.1|uniprotkb:F8VXB4	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:k2c8_human(display_long)|uniprotkb:Keratin-8(gene name synonym)|uniprotkb:KRT8(gene name)|psi-mi:KRT8(display_short)|uniprotkb:CYK8(gene name synonym)|uniprotkb:Cytokeratin-8(gene name synonym)|uniprotkb:Type-II keratin Kb8(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Batchelor et al. (2004)	imex:IM-27518|pubmed:14710194	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22229033|imex:IM-27518-7	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"refseq:NP_001243222.1|ensembl:ENSG00000170421.13(gene)|ensembl:ENST00000293308.11(transcript)|ensembl:ENST00000546897.5(transcript)|ensembl:ENST00000552551.5(transcript)|ensembl:ENST00000692008.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005882""(intermediate filament)|go:""GO:0005911""(cell-cell junction)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0030018""(Z disc)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0042383""(sarcolemma)|go:""GO:0043034""(costamere)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045095""(keratin filament)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045214""(sarcomere organization)|go:""GO:0051599""(response to hydrostatic pressure)|go:""GO:0051707""(response to other organism)|go:""GO:0060706""(cell differentiation involved in embryonic placenta development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P05787|rcsb pdb:7K3C|rcsb pdb:7K3X|rcsb pdb:7K3Y|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002264.1|dip:DIP-424N|panther:PTHR45616(orthology-group)"	"go:""GO:0005737""(cytoplasm)"	-	-	figure legend:fig.2c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/25	2024/11/14	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:zyV8eOjx426ehjJYK4jsizORUws9606	intact-crc:88C58189ADF1EC49|rigid:dN2UbABjynXCiPEchqGaY8rvkAc	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P05783	uniprotkb:B7UM99	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Batchelor et al. (2004)	imex:IM-27518|pubmed:14710194	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22229127|imex:IM-27518-11	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"go:""GO:0042995""(cell projection)"	-	-	figure legend:fig. 3,4|comment:Colocalization of Tir and CK18 in EPEC‐induced pedestals was also observed in the human intestinal epithelial INT407 and Caco‐2 cell lines.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/25	2025/03/25	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:3E323DBA66210812|rigid:VfXrurNnW99L71cDN2oN/BJy/Vw	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P05787	uniprotkb:B7UM99	intact:EBI-297852|uniprotkb:Q14099|uniprotkb:Q14716|uniprotkb:Q14717|uniprotkb:Q53GJ0|uniprotkb:Q6DHW5|uniprotkb:Q6GMY0|uniprotkb:Q6P4C7|uniprotkb:Q96J60|uniprotkb:A8K4H3|uniprotkb:B0AZN5|ensembl:ENSP00000293308.6|ensembl:ENSP00000447402.1|ensembl:ENSP00000447566.1|ensembl:ENSP00000509398.1|uniprotkb:F8VXB4	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:k2c8_human(display_long)|uniprotkb:Keratin-8(gene name synonym)|uniprotkb:KRT8(gene name)|psi-mi:KRT8(display_short)|uniprotkb:CYK8(gene name synonym)|uniprotkb:Cytokeratin-8(gene name synonym)|uniprotkb:Type-II keratin Kb8(gene name synonym)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Batchelor et al. (2004)	imex:IM-27518|pubmed:14710194	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22229135|imex:IM-27518-13	intact-miscore:0.46	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001243222.1|ensembl:ENSG00000170421.13(gene)|ensembl:ENST00000293308.11(transcript)|ensembl:ENST00000546897.5(transcript)|ensembl:ENST00000552551.5(transcript)|ensembl:ENST00000692008.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005882""(intermediate filament)|go:""GO:0005911""(cell-cell junction)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0030018""(Z disc)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0042383""(sarcolemma)|go:""GO:0043034""(costamere)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045095""(keratin filament)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045214""(sarcomere organization)|go:""GO:0051599""(response to hydrostatic pressure)|go:""GO:0051707""(response to other organism)|go:""GO:0060706""(cell differentiation involved in embryonic placenta development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P05787|rcsb pdb:7K3C|rcsb pdb:7K3X|rcsb pdb:7K3Y|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002264.1|dip:DIP-424N|panther:PTHR45616(orthology-group)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"go:""GO:0042995""(cell projection)"	-	-	figure legend:fig. 3|comment:Colocalization of Tir and CK18 in EPEC‐induced pedestals was also observed in the human intestinal epithelial INT407 and Caco‐2 cell lines.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/25	2024/11/14	rogid:zyV8eOjx426ehjJYK4jsizORUws9606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:93B4655B48271495|rigid:dN2UbABjynXCiPEchqGaY8rvkAc	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:O00401	uniprotkb:Q8X482	intact:EBI-957615|uniprotkb:Q7Z746|uniprotkb:A1JUI9|ensembl:ENSP00000223023.4	intact:EBI-22229752	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)|uniprotkb:Neural Wiskott-Aldrich syndrome protein(gene name synonym)	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	"psi-mi:""MI:0416""(fluorescence microscopy)"	Campellone et al. (2004)	imex:IM-27522|pubmed:15296718	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22229777|imex:IM-27522-5	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003932.3|dip:DIP-29042N|ensembl:ENSG00000106299.8(gene)|ensembl:ENST00000223023.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0008017""(microtubule binding)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0009617""(response to bacterium)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016050""(vesicle organization)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030050""(vesicle transport along actin filament)|go:""GO:0030478""(actin cap)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030695""(GTPase regulator activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051301""(cell division)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051653""(spindle localization)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1903526""(negative regulation of membrane tubulation)|go:""GO:2000370""(positive regulation of clathrin-dependent endocytosis)|go:""GO:2000402""(negative regulation of lymphocyte migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033927|interpro:IPR036936|mint:O00401|rcsb pdb:2FF3|rcsb pdb:2LNH|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|panther:PTHR13037(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	"go:""GO:0042995""(cell projection)"	-	-	"figure legend:fig. 5b|comment:""\""Fluorescent antibody staining of HeLa cells infected with KC12 expressing EspFU demonstrated that HA-tagged EHEC Tir and myc-tagged EspFU precisely colocalized beneath adherent bacteria (Figure 5B), suggesting that they may physically associate during pedestal formation.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/27	2025/02/28	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	intact-crc:B6272834EC8C39EC|rigid:ghnY3tuMdnA7Ye8yd9kJicYt4ZI	false	-	myc tag:?-?	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:B7UM99	uniprotkb:O00401	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-957615|uniprotkb:Q7Z746|uniprotkb:A1JUI9|ensembl:ENSP00000223023.4	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)|uniprotkb:Neural Wiskott-Aldrich syndrome protein(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Campellone et al. (2004)	imex:IM-27522|pubmed:15296718	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22229787|imex:IM-27522-7	intact-miscore:0.27	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"refseq:NP_003932.3|dip:DIP-29042N|ensembl:ENSG00000106299.8(gene)|ensembl:ENST00000223023.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0008017""(microtubule binding)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0009617""(response to bacterium)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016050""(vesicle organization)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030050""(vesicle transport along actin filament)|go:""GO:0030478""(actin cap)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030695""(GTPase regulator activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051301""(cell division)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051653""(spindle localization)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1903526""(negative regulation of membrane tubulation)|go:""GO:2000370""(positive regulation of clathrin-dependent endocytosis)|go:""GO:2000402""(negative regulation of lymphocyte migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033927|interpro:IPR036936|mint:O00401|rcsb pdb:2FF3|rcsb pdb:2LNH|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|panther:PTHR13037(orthology-group)"	"go:""GO:0042995""(cell projection)"	-	-	"figure legend:fig. 5b|comment:""\""Fluorescent antibody staining of HeLa cells infected with KC12 expressing EspFU demonstrated that HA-tagged EHEC Tir and myc-tagged EspFU precisely colocalized beneath adherent bacteria (Figure 5B), suggesting that they may physically associate during pedestal formation.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/27	2025/02/28	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	intact-crc:55E6804DCFD9A280|rigid:0bIKaaLFvPQHysNtEL1J8LDeyO0	false	ha tag:?-?	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:O00401	uniprotkb:Q8X482	intact:EBI-957615|uniprotkb:Q7Z746|uniprotkb:A1JUI9|ensembl:ENSP00000223023.4	intact:EBI-22229752	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)|uniprotkb:Neural Wiskott-Aldrich syndrome protein(gene name synonym)	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Campellone et al. (2004)	imex:IM-27522|pubmed:15296718	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22229812|imex:IM-27522-11	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003932.3|dip:DIP-29042N|ensembl:ENSG00000106299.8(gene)|ensembl:ENST00000223023.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0008017""(microtubule binding)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0009617""(response to bacterium)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016050""(vesicle organization)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030050""(vesicle transport along actin filament)|go:""GO:0030478""(actin cap)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030695""(GTPase regulator activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051301""(cell division)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051653""(spindle localization)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1903526""(negative regulation of membrane tubulation)|go:""GO:2000370""(positive regulation of clathrin-dependent endocytosis)|go:""GO:2000402""(negative regulation of lymphocyte migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033927|interpro:IPR036936|mint:O00401|rcsb pdb:2FF3|rcsb pdb:2LNH|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|panther:PTHR13037(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	-	-	-	figure legend:fig. 6b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/27	2025/02/28	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	intact-crc:0AC71D02E66AB049|rigid:ghnY3tuMdnA7Ye8yd9kJicYt4ZI	false	-	myc tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q8X482	uniprotkb:O00401	intact:EBI-22229752	intact:EBI-957615|uniprotkb:Q7Z746|uniprotkb:A1JUI9|ensembl:ENSP00000223023.4	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)|uniprotkb:Neural Wiskott-Aldrich syndrome protein(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Campellone et al. (2004)	imex:IM-27522|pubmed:15296718	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22229827|imex:IM-27522-13	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	"refseq:NP_003932.3|dip:DIP-29042N|ensembl:ENSG00000106299.8(gene)|ensembl:ENST00000223023.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0008017""(microtubule binding)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0009617""(response to bacterium)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016050""(vesicle organization)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030050""(vesicle transport along actin filament)|go:""GO:0030478""(actin cap)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030695""(GTPase regulator activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051301""(cell division)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051653""(spindle localization)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1903526""(negative regulation of membrane tubulation)|go:""GO:2000370""(positive regulation of clathrin-dependent endocytosis)|go:""GO:2000402""(negative regulation of lymphocyte migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033927|interpro:IPR036936|mint:O00401|rcsb pdb:2FF3|rcsb pdb:2LNH|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|panther:PTHR13037(orthology-group)"	-	-	-	figure legend:fig.6c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/27	2025/02/28	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	intact-crc:48121538693815E4|rigid:ghnY3tuMdnA7Ye8yd9kJicYt4ZI	false	binding-associated region:80-384|his tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q8X482	uniprotkb:O00401	intact:EBI-22229752	intact:EBI-957615|uniprotkb:Q7Z746|uniprotkb:A1JUI9|ensembl:ENSP00000223023.4	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)|uniprotkb:Neural Wiskott-Aldrich syndrome protein(gene name synonym)	"psi-mi:""MI:0047""(far western blotting)"	Campellone et al. (2004)	imex:IM-27522|pubmed:15296718	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22229833|imex:IM-27522-15	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	"refseq:NP_003932.3|dip:DIP-29042N|ensembl:ENSG00000106299.8(gene)|ensembl:ENST00000223023.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0008017""(microtubule binding)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0009617""(response to bacterium)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016050""(vesicle organization)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030050""(vesicle transport along actin filament)|go:""GO:0030478""(actin cap)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030695""(GTPase regulator activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051301""(cell division)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051653""(spindle localization)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1903526""(negative regulation of membrane tubulation)|go:""GO:2000370""(positive regulation of clathrin-dependent endocytosis)|go:""GO:2000402""(negative regulation of lymphocyte migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033927|interpro:IPR036936|mint:O00401|rcsb pdb:2FF3|rcsb pdb:2LNH|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|panther:PTHR13037(orthology-group)"	-	-	-	figure legend:fig.6c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/27	2025/02/28	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	intact-crc:373FC1665F5D523D|rigid:ghnY3tuMdnA7Ye8yd9kJicYt4ZI	false	binding-associated region:80-384|his tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q8X482	uniprotkb:O00401	intact:EBI-22229752	intact:EBI-957615|uniprotkb:Q7Z746|uniprotkb:A1JUI9|ensembl:ENSP00000223023.4	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)|uniprotkb:Neural Wiskott-Aldrich syndrome protein(gene name synonym)	"psi-mi:""MI:0049""(filter binding)"	Garmendia et al. (2004)	pubmed:15527496|imex:IM-27524	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22230090|imex:IM-27524-1	intact-miscore:0.69	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	"refseq:NP_003932.3|dip:DIP-29042N|ensembl:ENSG00000106299.8(gene)|ensembl:ENST00000223023.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0008017""(microtubule binding)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0009617""(response to bacterium)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016050""(vesicle organization)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030050""(vesicle transport along actin filament)|go:""GO:0030478""(actin cap)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030695""(GTPase regulator activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051301""(cell division)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051653""(spindle localization)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1903526""(negative regulation of membrane tubulation)|go:""GO:2000370""(positive regulation of clathrin-dependent endocytosis)|go:""GO:2000402""(negative regulation of lymphocyte migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033927|interpro:IPR036936|mint:O00401|rcsb pdb:2FF3|rcsb pdb:2LNH|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|panther:PTHR13037(orthology-group)"	-	-	-	figure legend:fig.9d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/27	2025/02/28	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	intact-crc:1517C4044FDDCA64|rigid:ghnY3tuMdnA7Ye8yd9kJicYt4ZI	false	his tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UM99	uniprotkb:P31946	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161.4|ensembl:ENSP00000361930.3	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Patel et al. (2006)	imex:IM-27538|pubmed:16367866	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22235202|imex:IM-27538-1	intact-miscore:0.53	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"panther:PTHR18860(orthology-group)|refseq:NP_003395.1|refseq:NP_647539.1|ensembl:ENSG00000166913.13(gene)|ensembl:ENST00000353703.9(transcript)|ensembl:ENST00000372839.7(transcript)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|rcsb pdb:8DP5|rcsb pdb:8EQ8|rcsb pdb:8EQH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9726840|reactome:R-HSA-9726842|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:XP_016883528.1|dip:DIP-743N|ensembl:ENSP00000300161.4|ensembl:ENSP00000361930.3"	-	-	-	figure legend:table 1 fig. 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/11/27	2025/03/20	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	intact-crc:432DFC2481CB2497|rigid:Z2uFRnVF56MXF8ZZbUV67JPCtaQ	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63104	uniprotkb:B7UM99	intact:EBI-347088|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6NUR9|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Patel et al. (2006)	imex:IM-27538|pubmed:16367866	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22235206|imex:IM-27538-3	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164924.18(gene)|ensembl:ENST00000353245.7(transcript)|ensembl:ENST00000395951.7(transcript)|ensembl:ENST00000395953.6(transcript)|ensembl:ENST00000395956.7(transcript)|ensembl:ENST00000395957.6(transcript)|ensembl:ENST00000395958.6(transcript)|ensembl:ENST00000419477.6(transcript)|ensembl:ENST00000457309.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001525""(angiogenesis)|go:""GO:0003016""(respiratory system process)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008039""(synaptic target recognition)|go:""GO:0008104""(protein localization)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030324""(lung development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031982""(vesicle)|go:""GO:0035148""(tube formation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0072562""(blood microparticle)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090168""(Golgi reassembly)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63104|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5J31|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|rcsb pdb:7MFD|rcsb pdb:7MFE|rcsb pdb:7MFF|rcsb pdb:7Q16|rcsb pdb:7ZIT|rcsb pdb:8A9G|rcsb pdb:8AH2|rcsb pdb:8QDV|rcsb pdb:8WE2|rcsb pdb:8WF6|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|efo:""Orphanet:178469""|panther:PTHR18860(orthology-group)|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1|ensembl:ENST00000522542.5|ensembl:ENSP00000430072.1"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	-	-	-	figure legend:table 1 fig. 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/11/27	2025/03/24	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:10846AE7F196236C|rigid:PehvWl+WYBHeqUvyjR/TGvHtOYo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UM99	uniprotkb:P27348	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Patel et al. (2006)	imex:IM-27538|pubmed:16367866	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22235210|imex:IM-27538-5	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"panther:PTHR18860(orthology-group)|refseq:NP_006817.1|ensembl:ENSG00000134308.14(gene)|ensembl:ENST00000238081.8(transcript)|ensembl:ENST00000381844.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034766""(negative regulation of monoatomic ion transmembrane transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045202""(synapse)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071889""(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|dip:DIP-27584N|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4"	-	-	-	figure legend:table 1 fig. 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/11/27	2025/02/28	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	intact-crc:584C16815B4EE499|rigid:GrNhrtVtL22nsGVuE0gQWfDfwDM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B7UM99	uniprotkb:P27348	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Patel et al. (2006)	imex:IM-27538|pubmed:16367866	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22235221|imex:IM-27538-7	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"panther:PTHR18860(orthology-group)|refseq:NP_006817.1|ensembl:ENSG00000134308.14(gene)|ensembl:ENST00000238081.8(transcript)|ensembl:ENST00000381844.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034766""(negative regulation of monoatomic ion transmembrane transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045202""(synapse)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071889""(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|dip:DIP-27584N|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4"	-	-	"comment:""\""in performing these experiments we noted that pGAD‐GH constructs missing the 3′ non‐coding region present in cDNA33 exhibited lower levels of β‐galactosidase activity in the yeast two‐hybrid assay irrespective of the codons at the beginning of the 14‐3‐3 reading frame (PJ69‐4A pICC10 + pNC701 and pICC10 + pNC720 of Fig. 1A).\"""""	"figure legend:table 1 fig. 1|comment:""\""None of these Tir subfragments showed β‐galactosidase activities above that of the host or single plasmid‐bearing control strains (Fig. 1B). In yeast, the complete Tir molecule is required for recognition by 14‐3‐3τ.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/11/27	2025/02/28	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	intact-crc:CADA3B63CD3860D9|rigid:GrNhrtVtL22nsGVuE0gQWfDfwDM	false	mutation with no effect:51-51|mutation with no effect:434-434|mutation with no effect:465-465	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UM99	uniprotkb:P27348	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Patel et al. (2006)	imex:IM-27538|pubmed:16367866	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22235390|imex:IM-27538-9	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"panther:PTHR18860(orthology-group)|refseq:NP_006817.1|ensembl:ENSG00000134308.14(gene)|ensembl:ENST00000238081.8(transcript)|ensembl:ENST00000381844.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034766""(negative regulation of monoatomic ion transmembrane transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045202""(synapse)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071889""(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|dip:DIP-27584N|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4"	-	-	-	figure legend:fig. 2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/27	2025/02/28	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	intact-crc:161205041624BF34|rigid:GrNhrtVtL22nsGVuE0gQWfDfwDM	false	his tag:?-?	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UM99	uniprotkb:P31946	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161.4|ensembl:ENSP00000361930.3	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	"psi-mi:""MI:0411""(enzyme linked immunosorbent assay)"	Patel et al. (2006)	imex:IM-27538|pubmed:16367866	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22235402|imex:IM-27538-11	intact-miscore:0.53	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"panther:PTHR18860(orthology-group)|refseq:NP_003395.1|refseq:NP_647539.1|ensembl:ENSG00000166913.13(gene)|ensembl:ENST00000353703.9(transcript)|ensembl:ENST00000372839.7(transcript)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|rcsb pdb:8DP5|rcsb pdb:8EQ8|rcsb pdb:8EQH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9726840|reactome:R-HSA-9726842|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:XP_016883528.1|dip:DIP-743N|ensembl:ENSP00000300161.4|ensembl:ENSP00000361930.3"	-	-	-	figure legend:fig. 2b|comment:By comparison at saturation of 14‐3‐3τ with Tir, the 14‐3‐3β isoform exhibited only 10% of the binding ability of the former.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/27	2025/03/20	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	intact-crc:8737A80A81B8A55F|rigid:Z2uFRnVF56MXF8ZZbUV67JPCtaQ	false	his tag:?-?	-	-	-	"psi-mi:""MI:0421""(identification by antibody)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UM99	uniprotkb:P27348	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Patel et al. (2006)	imex:IM-27538|pubmed:16367866	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22235416|imex:IM-27538-13	intact-miscore:0.66	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"panther:PTHR18860(orthology-group)|refseq:NP_006817.1|ensembl:ENSG00000134308.14(gene)|ensembl:ENST00000238081.8(transcript)|ensembl:ENST00000381844.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034766""(negative regulation of monoatomic ion transmembrane transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045202""(synapse)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071889""(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|dip:DIP-27584N|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4"	-	-	-	figure legend:fig 3|comment:The 14‐3‐3τ and cytokeratin 18 proteins were observed to co‐precipitate with Tir in the wild‐type EPEC‐infected membrane and cytoplasmic extracts but were absent in the ΔTir control.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/27	2025/03/25	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	intact-crc:DC0C241D89593868|rigid:knKCYXQ81d25e4Brc43hI8tN7a4	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B7UM99	uniprotkb:P05783	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Patel et al. (2006)	imex:IM-27538|pubmed:16367866	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22235416|imex:IM-27538-13	intact-miscore:0.66	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	-	-	-	figure legend:fig 3|comment:The 14‐3‐3τ and cytokeratin 18 proteins were observed to co‐precipitate with Tir in the wild‐type EPEC‐infected membrane and cytoplasmic extracts but were absent in the ΔTir control.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/27	2025/03/25	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	intact-crc:DC0C241D89593868|rigid:knKCYXQ81d25e4Brc43hI8tN7a4	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:B7UM99	uniprotkb:P27348	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Patel et al. (2006)	imex:IM-27538|pubmed:16367866	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22235421|imex:IM-27538-15	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"panther:PTHR18860(orthology-group)|refseq:NP_006817.1|ensembl:ENSG00000134308.14(gene)|ensembl:ENST00000238081.8(transcript)|ensembl:ENST00000381844.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034766""(negative regulation of monoatomic ion transmembrane transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045202""(synapse)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071889""(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|dip:DIP-27584N|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4"	-	-	-	figure legend:fig 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/27	2025/02/28	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	intact-crc:47700E6CA73E7307|rigid:GrNhrtVtL22nsGVuE0gQWfDfwDM	false	-	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P27348	uniprotkb:B7UM99	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Patel et al. (2006)	imex:IM-27538|pubmed:16367866	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22235436|imex:IM-27538-17	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR18860(orthology-group)|refseq:NP_006817.1|ensembl:ENSG00000134308.14(gene)|ensembl:ENST00000238081.8(transcript)|ensembl:ENST00000381844.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034766""(negative regulation of monoatomic ion transmembrane transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045202""(synapse)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071889""(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|dip:DIP-27584N|ensembl:ENSP00000238081.3|ensembl:ENSP00000371267.4"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"go:""GO:0042995""(cell projection)"	-	-	figure legend:fig. 4|comment:14‐3‐3τ was found throughout the host cell but was observed to accumulate adjacent to Tir localized at the extremity of the actin‐stained pedestal. The tips of the pedestals represent the interface of the bacterial attachment site and the location of Tir as it interacts with intimin|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/11/27	2025/02/28	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	intact-crc:39285956B2A6A5EE|rigid:GrNhrtVtL22nsGVuE0gQWfDfwDM	false	-	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q8X482	uniprotkb:Q14247	intact:EBI-22229752	intact:EBI-351886|intact:EBI-3959948|uniprotkb:Q8N707|uniprotkb:Q96H99|ensembl:ENSP00000301843.8|ensembl:ENSP00000500756.1	"psi-mi:espfu_eco57(display_long)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:""espF(U)""(gene name)|psi-mi:""espF(U)""(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:Z3072(locus name)"	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Cantarelli et al. (2007)	imex:IM-27552|pubmed:17451412	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22272907|imex:IM-27552-6	intact-miscore:0.27	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0030430""(host cell cytoplasm)|interpro:IPR044889|interpro:IPR006891(EspF protein)|mint:Q8X482"	"refseq:NP_005222.2|refseq:NP_612632.1|refseq:NP_001171669.1|ensembl:ENSG00000085733.16(gene)|ensembl:ENSG00000288401.1(gene)|ensembl:ENST00000301843.13(transcript)|ensembl:ENST00000671805.1(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0002102""(podosome)|go:""GO:0005522""(profilin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007165""(signal transduction)|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030516""(regulation of axon extension)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0043197""(dendritic spine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0045987""(positive regulation of smooth muscle contraction)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0048870""(cell motility)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097581""(lamellipodium organization)|go:""GO:1901524""(regulation of mitophagy)|go:""GO:1990023""(mitotic spindle midzone)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|dip:DIP-33190N"	"go:""GO:0042995""(cell projection)"	-	-	"figure legend:fig. 4c|comment:""\""Infection of HeLa cells with DMEM‐activated EHEC expressing FLAG‐tagged EspFu (as in Fig. 2C and D) resulted in a perfect colocalization of EspFu‐FLAG and tyrosine‐phosphorylated cortactin, which was visible 45 min after infection (Fig. 4C). As the infection proceeded (120 min), cortactin was dephosphorylated and only EspFu‐FLAG was detected near the bacteria.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/12/02	2025/03/11	rogid:5ta4O6gj+U5E7doG3zmjLy36nJ483334	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:51B36852E6872844|rigid:AffvIfSUbfE+9f/+4IHLjr9WDL0	false	flag tag:?-?	-	-	-	"psi-mi:""MI:0707""(anti tag immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q7DB77	uniprotkb:Q14247	intact:EBI-6480811|uniprotkb:Q7A9Q1|uniprotkb:Q9R396	intact:EBI-351886|intact:EBI-3959948|uniprotkb:Q8N707|uniprotkb:Q96H99|ensembl:ENSP00000301843.8|ensembl:ENSP00000500756.1	psi-mi:tir_eco57(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:espE(gene name synonym)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:Z5112(locus name)|uniprotkb:ECs4561(locus name)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Cantarelli et al. (2007)	imex:IM-27552|pubmed:17451412	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22274999|imex:IM-27552-20	intact-miscore:0.27	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001301454.1|interpro:IPR022638|interpro:IPR022639|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|rcsb pdb:2ZQK|rcsb pdb:2ZWK|interpro:IPR037003|mint:Q7DB77|refseq:NP_312588.1"	"refseq:NP_005222.2|refseq:NP_612632.1|refseq:NP_001171669.1|ensembl:ENSG00000085733.16(gene)|ensembl:ENSG00000288401.1(gene)|ensembl:ENST00000301843.13(transcript)|ensembl:ENST00000671805.1(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0002102""(podosome)|go:""GO:0005522""(profilin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007165""(signal transduction)|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030516""(regulation of axon extension)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0043197""(dendritic spine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0045987""(positive regulation of smooth muscle contraction)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0048870""(cell motility)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097581""(lamellipodium organization)|go:""GO:1901524""(regulation of mitophagy)|go:""GO:1990023""(mitotic spindle midzone)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|dip:DIP-33190N"	"go:""GO:0042995""(cell projection)"	-	-	"figure legend:fig. 5e|comment:""\""Furthermore, using immunofluorescence, Tir and tyrosine‐phosphorylated cortactin were found to colocalize beneath the attached bacteria in HeLa cells infected with DMEM‐activated EHEC for 45 min (Fig. 5E). Accordingly, due to the cortactin dephosphorylation, only Tir was detected in HeLa cells infected with EHEC for 120 min. Infection of HeLa cells with DMEM‐activated EHEC Δtir resulted in a complete failure to induce tyrosine phosphorylation of cortactin, as well as actin assembly (Fig. 5E, Δtir).\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2019/12/02	2025/03/11	rogid:w091zQ2yloHiTr07621yQtr7n0w83334	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:50B23D37620A9F45|rigid:f2eYnqQ2M783YtQMAV8mrYPfjUY	false	myc tag:?-?	-	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q8N302	uniprotkb:Q5NEC5	intact:EBI-747899|uniprotkb:O00581|uniprotkb:Q53YS3|uniprotkb:Q9BU84|uniprotkb:Q9NW66|intact:EBI-28984369|ensembl:ENSP00000316109.7	intact:EBI-22297545	psi-mi:aggf1_human(display_long)|uniprotkb:Angiogenic factor VG5Q(gene name synonym)|uniprotkb:Vasculogenesis gene on 5q protein(gene name synonym)|uniprotkb:G patch domain-containing protein 7(gene name synonym)|uniprotkb:AGGF1(gene name)|psi-mi:AGGF1(display_short)|uniprotkb:VG5Q(gene name synonym)|uniprotkb:GPATC7(gene name synonym)|uniprotkb:GPATCH7(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297557|imex:IM-27563-301	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:90308""|ensembl:ENSG00000164252.13(gene)|ensembl:ENST00000312916.12(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0007155""(cell adhesion)|go:""GO:0042802""(identical protein binding)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000467(D111/G-patch)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR035624|interpro:IPR041591|interpro:IPR053027|mint:Q8N302|reactome:R-HSA-6802952|refseq:NP_060516.2|panther:PTHR23106(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:5FA3UwL9w6K00rccLnd3fwIs8oo9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:7F50D5C0F46664E5|rigid:RV/3nK7T3GwzbxrTQfdC+QxLizs	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P23526	uniprotkb:Q5NHH2	intact:EBI-1053240|uniprotkb:Q96A36|uniprotkb:B3KUN3|uniprotkb:F5H737|uniprotkb:A8K307|uniprotkb:E1P5P2|ensembl:ENSP00000217426.2	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:sahh_human(display_long)|uniprotkb:S-adenosyl-L-homocysteine hydrolase(gene name synonym)|uniprotkb:AHCY(gene name)|psi-mi:AHCY(display_short)|uniprotkb:SAHH(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297567|imex:IM-27563-281	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:88618""|dip:DIP-50557N|ensembl:ENSG00000101444.13(gene)|ensembl:ENST00000217426.7(transcript)|go:""GO:0004013""(adenosylhomocysteinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0033353""(S-adenosylmethionine cycle)|go:""GO:0042470""(melanosome)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:P23526|rcsb pdb:1A7A|rcsb pdb:1LI4|rcsb pdb:3NJ4|rcsb pdb:4PFJ|rcsb pdb:4PGF|rcsb pdb:4YVF|rcsb pdb:5W49|rcsb pdb:5W4B|reactome:R-HSA-156581|reactome:R-HSA-1614635|reactome:R-HSA-2408508|reactome:R-HSA-5578997|refseq:NP_000678.1|refseq:NP_001155238.1|refseq:NP_001309013.1|refseq:NP_001309014.1|refseq:XP_005260374.1|refseq:XP_011526961.1|refseq:XP_016883197.1|refseq:XP_016883198.1|panther:PTHR23420(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/28	rogid:+y7rwgw9EIMaVrkt4/9kbZM44sg9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:BC0F08784E37ACE4|rigid:DS0izCYLzJvB7EQucqNAuXbl5T8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15121	uniprotkb:Q5NFP9	intact:EBI-1052491|uniprotkb:Q5U031|uniprotkb:Q9BS21|uniprotkb:Q9UCI9|uniprotkb:B2R8N3|uniprotkb:Q6FGA4|uniprotkb:Q6ICP2|ensembl:ENSP00000285930.3	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:aldr_human(display_long)|uniprotkb:Aldehyde reductase(gene name synonym)|uniprotkb:ALR2(gene name synonym)|uniprotkb:Aldose reductase(gene name synonym)|uniprotkb:AKR1B1(gene name)|psi-mi:AKR1B1(display_short)|uniprotkb:ALDR1(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297577|imex:IM-27563-461	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001619.1|ensembl:ENSG00000085662.14(gene)|ensembl:ENST00000285930.9(transcript)|go:""GO:0001523""(retinoid metabolic process)|go:""GO:0001758""(retinal dehydrogenase activity)|go:""GO:0002070""(epithelial cell maturation)|go:""GO:0003091""(renal water homeostasis)|go:""GO:0004032""(""aldose reductase (NADPH) activity"")|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006700""(C21-steroid hormone biosynthetic process)|go:""GO:0009055""(electron transfer activity)|go:""GO:0019853""(L-ascorbic acid biosynthetic process)|go:""GO:0035809""(regulation of urine volume)|go:""GO:0036130""(prostaglandin H2 endoperoxidase reductase activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043795""(glyceraldehyde oxidoreductase activity)|go:""GO:0044597""(daunorubicin metabolic process)|go:""GO:0044598""(doxorubicin metabolic process)|go:""GO:0046370""(fructose biosynthetic process)|go:""GO:0047655""(allyl-alcohol dehydrogenase activity)|go:""GO:0047939""(L-glucuronate reductase activity)|go:""GO:0047956""(""glycerol dehydrogenase (NADP+) activity"")|go:""GO:0052650""(""all-trans-retinol dehydrogenase (NADP+) activity"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0071475""(cellular hyperosmotic salinity response)|go:""GO:0072205""(metanephric collecting duct development)|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|mint:P15121|rcsb pdb:1ABN|rcsb pdb:1ADS|rcsb pdb:1AZ1|rcsb pdb:1AZ2|rcsb pdb:1EF3|rcsb pdb:1EL3|rcsb pdb:1IEI|rcsb pdb:1MAR|rcsb pdb:1PWL|rcsb pdb:1PWM|rcsb pdb:1T40|rcsb pdb:1T41|rcsb pdb:1US0|rcsb pdb:1X96|rcsb pdb:1X97|rcsb pdb:1X98|rcsb pdb:1XGD|rcsb pdb:1Z3N|rcsb pdb:1Z89|rcsb pdb:1Z8A|rcsb pdb:2ACQ|rcsb pdb:2ACR|rcsb pdb:2ACS|rcsb pdb:2ACU|rcsb pdb:2AGT|rcsb pdb:2DUX|rcsb pdb:2DUZ|rcsb pdb:2DV0|rcsb pdb:2F2K|rcsb pdb:2FZ8|rcsb pdb:2FZ9|rcsb pdb:2FZB|rcsb pdb:2FZD|rcsb pdb:2HV5|rcsb pdb:2HVN|rcsb pdb:2HVO|rcsb pdb:2I16|rcsb pdb:2I17|rcsb pdb:2IKG|rcsb pdb:2IKH|rcsb pdb:2IKI|rcsb pdb:2IKJ|rcsb pdb:2INE|rcsb pdb:2INZ|rcsb pdb:2IPW|rcsb pdb:2IQ0|rcsb pdb:2IQD|rcsb pdb:2IS7|rcsb pdb:2ISF|rcsb pdb:2J8T|rcsb pdb:2NVC|rcsb pdb:2NVD|rcsb pdb:2PD5|rcsb pdb:2PD9|rcsb pdb:2PDB|rcsb pdb:2PDC|rcsb pdb:2PDF|rcsb pdb:2PDG|rcsb pdb:2PDH|rcsb pdb:2PDI|rcsb pdb:2PDJ|rcsb pdb:2PDK|rcsb pdb:2PDL|rcsb pdb:2PDM|rcsb pdb:2PDN|rcsb pdb:2PDP|rcsb pdb:2PDQ|rcsb pdb:2PDU|rcsb pdb:2PDW|rcsb pdb:2PDX|rcsb pdb:2PDY|rcsb pdb:2PEV|rcsb pdb:2PF8|rcsb pdb:2PFH|rcsb pdb:2PZN|rcsb pdb:2QXW|rcsb pdb:2R24|rcsb pdb:3BCJ|rcsb pdb:3DN5|rcsb pdb:3G5E|rcsb pdb:3GHR|rcsb pdb:3GHS|rcsb pdb:3GHT|rcsb pdb:3GHU|rcsb pdb:3LBO|rcsb pdb:3LD5|rcsb pdb:3LEN|rcsb pdb:3LEP|rcsb pdb:3LQG|rcsb pdb:3LQL|rcsb pdb:3LZ3|rcsb pdb:3LZ5|rcsb pdb:3M0I|rcsb pdb:3M4H|rcsb pdb:3M64|rcsb pdb:3MB9|rcsb pdb:3MC5|rcsb pdb:3ONB|rcsb pdb:3ONC|rcsb pdb:3P2V|rcsb pdb:3Q65|rcsb pdb:3Q67|rcsb pdb:3RX2|rcsb pdb:3RX3|rcsb pdb:3RX4|rcsb pdb:3S3G|rcsb pdb:3T42|rcsb pdb:3U2C|rcsb pdb:3V35|rcsb pdb:3V36|rcsb pdb:4GCA|rcsb pdb:4GQ0|rcsb pdb:4IGS|rcsb pdb:4JIR|rcsb pdb:4LAU|rcsb pdb:4LAZ|rcsb pdb:4LB3|rcsb pdb:4LB4|rcsb pdb:4LBR|rcsb pdb:4LBS|rcsb pdb:4NKC|rcsb pdb:4PR4|rcsb pdb:4PRR|rcsb pdb:4PRT|rcsb pdb:4PUU|rcsb pdb:4PUW|rcsb pdb:4Q7B|rcsb pdb:4QBX|rcsb pdb:4QR6|rcsb pdb:4QX4|rcsb pdb:4QXI|rcsb pdb:4RPQ|rcsb pdb:4XZH|rcsb pdb:4XZI|rcsb pdb:4YS1|rcsb pdb:4YU1|rcsb pdb:5HA7|rcsb pdb:5OU0|rcsb pdb:5OUJ|rcsb pdb:5OUK|rcsb pdb:6F7R|rcsb pdb:6F81|rcsb pdb:6F82|rcsb pdb:6F84|rcsb pdb:6F8O|rcsb pdb:6SYW|rcsb pdb:6T27|rcsb pdb:6T3P|rcsb pdb:6T5G|rcsb pdb:6T7Q|rcsb pdb:6TD8|rcsb pdb:6TUC|rcsb pdb:6TUF|rcsb pdb:6TXP|rcsb pdb:6XUM|rcsb pdb:6Y03|rcsb pdb:6Y1P|rcsb pdb:8A4N|rcsb pdb:8AE9|rcsb pdb:8AQG|rcsb pdb:8AQP|rcsb pdb:8AUU|rcsb pdb:8B34|rcsb pdb:8B3N|rcsb pdb:8B3R|rcsb pdb:8B66|rcsb pdb:8BJL|rcsb pdb:8CNF|rcsb pdb:8CNP|rcsb pdb:8FH5|rcsb pdb:8FH6|rcsb pdb:8FH7|rcsb pdb:8FH8|rcsb pdb:8FH9|rcsb pdb:8OZ2|rcsb pdb:8P2R|reactome:R-HSA-196108|reactome:R-HSA-5652227|panther:PTHR11732(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:4uLYatk0qP+BBr1brwQ2q5Y9oQk9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:009FEF43D60E8785|rigid:zW5DxExzmJvIL0EWxyJnQrtfxEQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P56385	uniprotkb:Q5NHH2	intact:EBI-2270000|uniprotkb:Q0D2L9|ensembl:ENSP00000306003.4	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:atp5i_human(display_long)|uniprotkb:ATP5ME(gene name)|psi-mi:ATP5ME(display_short)|uniprotkb:ATP5I(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)|uniprotkb:ATP5K(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297698|imex:IM-27563-603	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009031.1|ensembl:ENSG00000169020.10(gene)|ensembl:ENST00000304312.5(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0015078""(proton transmembrane transporter activity)|go:""GO:0015986""(proton motive force-driven ATP synthesis)|go:""GO:0042776""(proton motive force-driven mitochondrial ATP synthesis)|go:""GO:0045259""(proton-transporting ATP synthase complex)|go:""GO:0045263""(""obsolete proton-transporting ATP synthase complex, coupling factor F(o)"")|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:P56385|rcsb pdb:8H9F|rcsb pdb:8H9J|rcsb pdb:8H9M|rcsb pdb:8H9Q|rcsb pdb:8H9S|rcsb pdb:8H9T|rcsb pdb:8H9U|rcsb pdb:8H9V|rcsb pdb:8KHF|rcsb pdb:8KI3|reactome:R-HSA-163210|reactome:R-HSA-8949613|panther:PTHR12427(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:NYpqzWQYASXwSwU/BYDTMU2tJjI9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:188BE4E4BF48BD78|rigid:piVUMOlnY+16QPmoelFZtxSjl+0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N8A2	uniprotkb:Q5NES6	intact:EBI-1245329|uniprotkb:Q6P480|uniprotkb:Q86VL5|uniprotkb:Q8IZ72|uniprotkb:Q9UFA4|uniprotkb:Q53SL9|ensembl:ENSP00000282272.9	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:anr44_human(display_long)|uniprotkb:ANKRD44(gene name)|psi-mi:ANKRD44(display_short)|uniprotkb:Ankyrin repeat domain-containing protein 44(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297607|imex:IM-27563-541	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001182073.1|refseq:NP_710181.2|ensembl:ENSG00000065413.20(gene)|ensembl:ENST00000282272.15(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:Q8N8A2|refseq:XP_005247005.1|panther:PTHR24123(orthology-group)	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:Vi+efSZ2F/weEJsGibCJCwhwlXs9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:2D75D3007EA559A2|rigid:jSdyaWnqs0YHUWuTh0eC1Kz23RQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q68CP9	uniprotkb:Q5NHT8	intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044.6	intact:EBI-2806309	psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297678|imex:IM-27563-5	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000189079.18(gene)|ensembl:ENST00000334344.11(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006337""(nucleosome disassembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|interpro:IPR003150(DNA-binding RFX)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0042592""(homeostatic process)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0048568""(embryonic organ development)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|interpro:IPR052406|mint:Q68CP9|rcsb pdb:7VDV|rcsb pdb:7Y8R|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_001334768.1|refseq:NP_689854.2|dip:DIP-33391N|efo:""Orphanet:1465"""	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/17	rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:25FAE821AAD1B2DF|rigid:Y6nhSXsxUbV3oi8PoBW/UYHb8wI	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y4X0	uniprotkb:Q5NHT8	intact:EBI-8583355|ensembl:ENSP00000262844.5|uniprotkb:Q8WX22|intact:MINT-3086664|uniprotkb:Q5JYV9|uniprotkb:Q6P9D8|uniprotkb:Q9UIQ8	intact:EBI-2806309	psi-mi:ammr1_human(display_long)|uniprotkb:AMMECR1(gene name)|psi-mi:AMMECR1(display_short)|uniprotkb:AMME syndrome candidate gene 1 protein(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297587|imex:IM-27563-601	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000101935.13(gene)|ensembl:ENST00000262844.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|interpro:IPR002733(AMMECR1)|interpro:IPR023473|interpro:IPR027485|interpro:IPR036071|mint:Q9Y4X0|refseq:NP_001020751.1|refseq:NP_001165160.1|refseq:NP_056180.1|efo:""Orphanet:86818""|panther:PTHR13016(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	"comment:mint|comment:homomint|function:""\""Defects in AMMECR1 may be a cause of AMME complex [MIM:300194]; also known as Alport syndrome with mental retardation, midface hypoplasia and elliptocytosis. The AMME complex is a contiguous gene deletion syndrome\"""""	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/24	rogid:epeJrGQt5CbnPII1/FSttS0KzwE9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:3E4461E7A6073D52|rigid:MpKW2G8a3qiV9KuGW+5PKB+Zjj0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5NHH2	uniprotkb:A6NEK1	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	intact:EBI-6873205	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	psi-mi:arrd5_human(display_long)|uniprotkb:ARRDC5(gene name)|psi-mi:ARRDC5(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297688|imex:IM-27563-105	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	"go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|refseq:NP_001073992.1|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR050357|mint:A6NEK1|panther:PTHR11188(orthology-group)"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	rogid:8mlgTh40pjWOuZvc96KfxGng6VU9606	intact-crc:CB01C9C0DA4F73B6|rigid:iCuh1crDxUv3rXDbElksdYr0AIs	false	tag:n-n	tag:c-c	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P52566	uniprotkb:Q5NES6	intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945.4|ensembl:ENSP00000440560.1|ensembl:ENSP00000444860.1	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297668|imex:IM-27563-103	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001166.3|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|ensembl:ENSG00000111348.9(gene)|ensembl:ENST00000228945.9(transcript)|ensembl:ENST00000541546.5(transcript)|ensembl:ENST00000541644.5(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005094""(Rho GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071461""(cellular response to redox state)|go:""GO:1901164""(negative regulation of trophoblast cell migration)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|dip:DIP-40959N|panther:PTHR10980(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:7038464BA8B5EDF8|rigid:Sm7gBHeCgrdO34JjcH8woJfi7f4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UM13	uniprotkb:Q5NEC5	intact:EBI-1266437|uniprotkb:Q2V500|uniprotkb:Q9UG51|uniprotkb:Q9Y5R0|uniprotkb:D3DNZ7|ensembl:ENSP00000310071.5|ensembl:ENSP00000403891.2|ensembl:ENSP00000423995.1|ensembl:ENSP00000478501.1	intact:EBI-22297545	psi-mi:apc10_human(display_long)|uniprotkb:ANAPC10(gene name)|psi-mi:ANAPC10(display_short)|uniprotkb:APC10(gene name synonym)|uniprotkb:Cyclosome subunit 10(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297597|imex:IM-27563-101	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055700.2|refseq:NP_001243635.1|refseq:NP_001243636.1|refseq:NP_001243637.1|refseq:NP_001243638.1|refseq:NP_001243639.1|ensembl:ENSG00000164162.14(gene)|ensembl:ENST00000309439.9(transcript)|ensembl:ENST00000451299.6(transcript)|ensembl:ENST00000507656.6(transcript)|ensembl:ENST00000613466.4(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005680""(anaphase-promoting complex)|go:""GO:0005829""(cytosol)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0031145""(anaphase-promoting complex-dependent catabolic process)|go:""GO:0051301""(cell division)|go:""GO:0051445""(regulation of meiotic cell cycle)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0141198""(protein branched polyubiquitination)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR016901(Anaphase-promoting complex, subunit 10, subgroup)|mint:Q9UM13|rcsb pdb:1JHJ|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|rcsb pdb:8PKP|rcsb pdb:8TAR|rcsb pdb:8TAU|rcsb pdb:9GAW|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_011529826.1|refseq:NP_001305296.1|dip:DIP-39885N|panther:PTHR12936(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/21	rogid:kKLo92DrTuOsaeowcNSWKe7xyn49606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:F0E5F98C981A059D|rigid:TZLuenmaizEHYSTM6WNs1tz3Sa4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:B4E2M5	uniprotkb:Q5NEM9	intact:EBI-22297617|ensembl:ENSP00000454770.2	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:anr66_human(display_long)|uniprotkb:ANKRD66(gene name)|psi-mi:ANKRD66(display_short)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297628|imex:IM-27563-1	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	ensembl:ENSG00000230062.7(gene)|ensembl:ENST00000565422.3(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR050776|mint:B4E2M5|panther:PTHR24201(orthology-group)|refseq:NP_001155907.2	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:VU5Q6GaOfMvcPF5DJBKTdZ05Gf09606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:11681EC5FF578093|rigid:8FR6VfIXb+2WLOj665bR758y1EM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2T2	uniprotkb:Q5NEM9	intact:EBI-2371151|uniprotkb:Q5JQ12|uniprotkb:Q9H5L2|ensembl:ENSP00000347408.4|ensembl:ENSP00000361831.1	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:ap3m1_human(display_long)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu-1(gene name synonym)|uniprotkb:AP3M1(gene name)|psi-mi:AP3M1(display_short)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:Mu3A-adaptin(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297648|imex:IM-27563-361	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001307192.1|refseq:NP_001307193.1|ensembl:ENSG00000185009.13(gene)|ensembl:ENST00000355264.9(transcript)|ensembl:ENST00000372745.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030131""(clathrin adaptor complex)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0046907""(intracellular transport)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0098837""(postsynaptic recycling endosome)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR050431|mint:Q9Y2T2|reactome:R-HSA-390471|refseq:NP_036227.1|refseq:NP_996895.1|panther:PTHR10529(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:VsXYkOxEite1RzT1YHCA6/U4gj09606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:C18DDA2AEC53F825|rigid:0UlfXPFaATOt/KCTZVC8cp7TThs	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13367	uniprotkb:Q5NES6	intact:EBI-1642811|uniprotkb:O14808|uniprotkb:Q52LY8|uniprotkb:A4Z4T7|uniprotkb:B7ZKR7|uniprotkb:B7ZKS0|ensembl:ENSP00000499235.1|intact:EBI-28985906	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:ap3b2_human(display_long)|uniprotkb:AP3B2(gene name)|psi-mi:AP3B2(display_short)|uniprotkb:Adaptor protein complex AP-3 subunit beta-2(gene name synonym)|uniprotkb:Beta-3B-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta-2 large chain(gene name synonym)|uniprotkb:Neuron-specific vesicle coat protein beta-NAP(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta-2(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297638|imex:IM-27563-3	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000103723.17(gene)|ensembl:ENST00000668990.2(transcript)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0016183""(synaptic vesicle coating)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0046907""(intracellular transport)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0098793""(presynapse)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|mint:Q13367|refseq:NP_001265440.1|refseq:NP_001265441.1|refseq:NP_001335370.1|refseq:NP_004635.2|efo:""Orphanet:442835""|panther:PTHR11134(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:UpuB/FVFDHPUjAf40y3SxOL9xzA9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:A91DC3ABE2DC54AF|rigid:JCOtaxoUZHh5Voyd8PdlQ/g3P88	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P52566	uniprotkb:Q5NHT8	intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945.4|ensembl:ENSP00000440560.1|ensembl:ENSP00000444860.1	intact:EBI-2806309	psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297658|imex:IM-27563-201	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001166.3|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|ensembl:ENSG00000111348.9(gene)|ensembl:ENST00000228945.9(transcript)|ensembl:ENST00000541546.5(transcript)|ensembl:ENST00000541644.5(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005094""(Rho GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071461""(cellular response to redox state)|go:""GO:1901164""(negative regulation of trophoblast cell migration)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|dip:DIP-40959N|panther:PTHR10980(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:948604E350E4CDC8|rigid:XlhAh5HQqZXkBLiYJrfmje+0sH4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86VG3	uniprotkb:Q5NHH2	intact:EBI-3923037|uniprotkb:Q96DD6|uniprotkb:D3DR18|ensembl:ENSP00000334848.5|ensembl:ENSP00000403937.3|ensembl:ENSP00000431374.2|ensembl:ENSP00000432685.2|ensembl:ENSP00000433407.2|ensembl:ENSP00000483671.1|ensembl:ENSP00000503448.1|ensembl:ENSP00000504720.1	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:iftap_human(display_long)|uniprotkb:IFTAP(gene name)|psi-mi:IFTAP(display_short)|uniprotkb:C11orf74(gene name synonym)|uniprotkb:NWC(gene name synonym)|uniprotkb:Protein HEPIS(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297801|imex:IM-27563-11	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011518187.1|refseq:XP_006718201.1|ensembl:ENSG00000166352.18(gene)|ensembl:ENST00000334307.10(transcript)|ensembl:ENST00000446510.6(transcript)|ensembl:ENST00000530697.6(transcript)|ensembl:ENST00000531554.6(transcript)|ensembl:ENST00000532470.3(transcript)|ensembl:ENST00000617650.5(transcript)|ensembl:ENST00000676979.1(transcript)|ensembl:ENST00000678060.1(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007340""(acrosome reaction)|go:""GO:0097731""(9+0 non-motile cilium)|go:""GO:0120160""(intraciliary transport particle A binding)|interpro:IPR040028|mint:Q86VG3|refseq:NP_001263651.1|refseq:NP_001263652.1|refseq:NP_001263653.1|refseq:NP_001263654.1|refseq:NP_001263655.1|refseq:NP_001263656.1|refseq:NP_620142.2|panther:PTHR35543(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:oLcIB5xXVb7erU+hZ8Bgt//y/4A9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:74E5A459305E6F20|rigid:PCqAyGWuIw7YnppdVzJ56MZcBDc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35226	uniprotkb:Q5NFP9	intact:EBI-2341576|ensembl:ENSP00000365851.3|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297781|imex:IM-27563-381	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168283.14(gene)|ensembl:ENST00000376663.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000792""(heterochromatin)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006346""(DNA methylation-dependent constitutive heterochromatin formation)|go:""GO:0006959""(humoral immune response)|go:""GO:0007379""(segment specification)|go:""GO:0007420""(brain development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016604""(nuclear body)|go:""GO:0021903""(rostrocaudal neural tube patterning)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031519""(PcG protein complex)|go:""GO:0033092""(positive regulation of immature T cell proliferation in thymus)|go:""GO:0035102""(PRC1 complex)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0048103""(somatic stem cell division)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0051443""(positive regulation of ubiquitin-protein transferase activity)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071535""(RING-like zinc finger domain binding)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090183""(regulation of kidney development)|go:""GO:0097027""(ubiquitin-protein transferase activator activity)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000011""(regulation of adaxial/abaxial pattern formation)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|rcsb pdb:8GRM|rcsb pdb:8PP7|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|refseq:NP_001190991.1|refseq:NP_005171.4|dip:DIP-41879N|panther:PTHR10825(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:F0ACF0377196673E|rigid:DXplko2rwQE+xGHH3W18uwbfu90	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5SZJ8	uniprotkb:Q5NHH2	intact:EBI-16579518|ensembl:ENSP00000359782.3|uniprotkb:Q4G0W8|uniprotkb:Q8N662|uniprotkb:Q96NS6	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:bend6_human(display_long)|uniprotkb:BEND6(gene name)|psi-mi:BEND6(display_short)|uniprotkb:C6orf65(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297771|imex:IM-27563-107	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000151917.18(gene)|ensembl:ENST00000370746.8(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0007399""(nervous system development)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|interpro:IPR018379|interpro:IPR037496|mint:Q5SZJ8|rcsb pdb:7YUL|rcsb pdb:7YUN|refseq:NP_001305468.1|refseq:NP_689944.2|refseq:XP_005248946.1|refseq:XP_016865895.1|refseq:XP_016865896.1|panther:PTHR35346(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:m1j2ZPgMQKg4ibux5XsEls16f0o9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:2C671E41F68DA940|rigid:EMzB+yh7DL5RbMUHIgTbEip2d50	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86VG3	uniprotkb:Q5NFP9	intact:EBI-3923037|uniprotkb:Q96DD6|uniprotkb:D3DR18|ensembl:ENSP00000334848.5|ensembl:ENSP00000403937.3|ensembl:ENSP00000431374.2|ensembl:ENSP00000432685.2|ensembl:ENSP00000433407.2|ensembl:ENSP00000483671.1|ensembl:ENSP00000503448.1|ensembl:ENSP00000504720.1	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:iftap_human(display_long)|uniprotkb:IFTAP(gene name)|psi-mi:IFTAP(display_short)|uniprotkb:C11orf74(gene name synonym)|uniprotkb:NWC(gene name synonym)|uniprotkb:Protein HEPIS(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297811|imex:IM-27563-287	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011518187.1|refseq:XP_006718201.1|ensembl:ENSG00000166352.18(gene)|ensembl:ENST00000334307.10(transcript)|ensembl:ENST00000446510.6(transcript)|ensembl:ENST00000530697.6(transcript)|ensembl:ENST00000531554.6(transcript)|ensembl:ENST00000532470.3(transcript)|ensembl:ENST00000617650.5(transcript)|ensembl:ENST00000676979.1(transcript)|ensembl:ENST00000678060.1(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007340""(acrosome reaction)|go:""GO:0097731""(9+0 non-motile cilium)|go:""GO:0120160""(intraciliary transport particle A binding)|interpro:IPR040028|mint:Q86VG3|refseq:NP_001263651.1|refseq:NP_001263652.1|refseq:NP_001263653.1|refseq:NP_001263654.1|refseq:NP_001263655.1|refseq:NP_001263656.1|refseq:NP_620142.2|panther:PTHR35543(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:oLcIB5xXVb7erU+hZ8Bgt//y/4A9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:2807AE462E09004D|rigid:dgze4AZ3AxCfHeveNqKEeKzI0Gs	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14867	uniprotkb:Q5NGJ5	intact:EBI-1263541|uniprotkb:O43285|ensembl:ENSP00000286800.3|ensembl:ENSP00000382805.1|uniprotkb:Q6ICU0	intact:EBI-22297738|uniprotkb:A0A0G2RPF6	psi-mi:bach1_human(display_long)|uniprotkb:BACH1(gene name)|psi-mi:BACH1(display_short)|uniprotkb:BTB and CNC homolog 1(gene name synonym)|uniprotkb:HA2303(gene name synonym)	psi-mi:q5ngj5_fratt(display_long)|uniprotkb:FTT_0842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297751|imex:IM-27563-283	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-24223N|refseq:NP_001177.1|refseq:NP_996749.1|ensembl:ENSG00000156273.16(gene)|ensembl:ENST00000286800.8(transcript)|ensembl:ENST00000399921.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0019222""(regulation of metabolic process)|go:""GO:0020037""(heme binding)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0098531""(ligand-modulated transcription factor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR043321|interpro:IPR046347|interpro:IPR050457|mint:O14867|rcsb pdb:2IHC|reactome:R-HSA-9707587|reactome:R-HSA-9707616|reactome:R-HSA-9708530|reactome:R-HSA-9818027|panther:PTHR46105(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|interpro:IPR050330|refseq:WP_003020808.1|refseq:YP_169847.1|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|mint:Q5NGJ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:8z/lJRahlkaHjT3j2jqOEH+koaA9606	rogid:/Dq7r5H2A4RbaDlrrHYQHMOGtbc177416	intact-crc:0800F95571462D73|rigid:zEE6+F9RXvYvua9Vxgu6+S5QCjg	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ND07	uniprotkb:Q5NEQ5	intact:EBI-22297838|ensembl:ENSP00000377577.3|uniprotkb:Q0P604|uniprotkb:Q9H5P8	intact:EBI-2808269|uniprotkb:A0A0G2RQ71	psi-mi:bbof1_human(display_long)|uniprotkb:Coiled-coil domain-containing protein 176(gene name synonym)|uniprotkb:BBOF1(gene name)|psi-mi:BBOF1(display_short)|uniprotkb:C14orf45(gene name synonym)|uniprotkb:CCDC176(gene name synonym)	psi-mi:q5neq5_fratt(display_long)|uniprotkb:Polyphosphate kinase PPK2(gene name synonym)|uniprotkb:FTT_1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297865|imex:IM-27563-13	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000119636.16(gene)|ensembl:ENST00000394009.5(transcript)|go:""GO:0005930""(axoneme)|go:""GO:0007026""(negative regulation of microtubule depolymerization)|go:""GO:0007288""(sperm axoneme assembly)|go:""GO:0007338""(single fertilization)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0036064""(ciliary basal body)|go:""GO:0036126""(sperm flagellum)|go:""GO:0044458""(motile cilium assembly)|go:""GO:0050821""(protein stabilization)|interpro:IPR032777|mint:Q8ND07|panther:PTHR14845(orthology-group)|refseq:NP_079333.2"	"interpro:IPR016898(Polyphosphate kinase 2, predicted)|interpro:IPR022488|interpro:IPR022486|refseq:YP_170487.1|refseq:WP_003014894.1|interpro:IPR027417|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0046872""(metal ion binding)|rcsb pdb:4YEG|rcsb pdb:5LL0|rcsb pdb:5LLB|rcsb pdb:5LLF|mint:Q5NEQ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:Vum2/kznYFVHcPAegGT8frMgV7E9606	rogid:3hIShFXVmkZdI9gV6zbu32j30jM177416	intact-crc:B4E9543A61DD4167|rigid:8MvEQFRj4Mcrrbp9ubqpa4zyIVY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75787	uniprotkb:Q5NHH2	intact:EBI-2512037|uniprotkb:Q8NG15|uniprotkb:Q8NBP3|uniprotkb:Q5QTQ7|uniprotkb:Q9UG89|uniprotkb:Q96FV6|uniprotkb:Q9H2P8|uniprotkb:Q96LB5|uniprotkb:Q6T7F5|uniprotkb:B7Z9I3|ensembl:ENSP00000490083.1	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	"psi-mi:renr_human(display_long)|uniprotkb:ATP6AP2(gene name)|psi-mi:ATP6AP2(display_short)|uniprotkb:ATP6IP2(gene name synonym)|uniprotkb:CAPER(gene name synonym)|uniprotkb:ELDF10(gene name synonym)|uniprotkb:Renin/prorenin receptor(gene name synonym)|uniprotkb:""ATPase H(+)-transporting lysosomal accessory protein 2""(gene name synonym)|uniprotkb:""ATPase H(+)-transporting lysosomal-interacting protein 2""(gene name synonym)|uniprotkb:Vacuolar ATP synthase membrane sector-associated protein M8-9(gene name synonym)|uniprotkb:N14F(gene name synonym)|uniprotkb:Embryonic liver differentiation factor 10(gene name synonym)|uniprotkb:HT028(orf name)|uniprotkb:MSTP009(orf name)|uniprotkb:PSEC0072(orf name)|uniprotkb:ER-localized type I transmembrane adapter(gene name synonym)"	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297708|imex:IM-27563-7	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:363654""|efo:""Orphanet:93952""|ensembl:ENSG00000182220.15(gene)|ensembl:ENST00000636580.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000220""(vacuolar proton-transporting V-type ATPase, V0 domain)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0002003""(angiotensin maturation)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007035""(vacuolar acidification)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0021626""(central nervous system maturation)|go:""GO:0021903""(rostrocaudal neural tube patterning)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030424""(axon)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0032591""(dendritic spine membrane)|go:""GO:0032914""(positive regulation of transforming growth factor beta1 production)|go:""GO:0033176""(proton-transporting V-type ATPase complex)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0048069""(eye pigmentation)|go:""GO:0048388""(endosomal lumen acidification)|go:""GO:0051452""(intracellular pH reduction)|go:""GO:0060323""(head morphogenesis)|go:""GO:0061795""(Golgi lumen acidification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097401""(synaptic vesicle lumen acidification)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1902600""(proton transmembrane transport)|interpro:IPR012493(Renin receptor-like)|mint:O75787|rcsb pdb:3LBS|rcsb pdb:3LC8|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|rcsb pdb:7U4T|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:NP_005756.2|panther:PTHR13351(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:v4lEPX23LdYqPi8dQX4MZG+tQZg9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:E6EC79B4748D3099|rigid:NVuzWWn4sBNG0rYYD4j56TCfvrY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ND07	uniprotkb:Q5NHT8	intact:EBI-22297838|ensembl:ENSP00000377577.3|uniprotkb:Q0P604|uniprotkb:Q9H5P8	intact:EBI-2806309	psi-mi:bbof1_human(display_long)|uniprotkb:Coiled-coil domain-containing protein 176(gene name synonym)|uniprotkb:BBOF1(gene name)|psi-mi:BBOF1(display_short)|uniprotkb:C14orf45(gene name synonym)|uniprotkb:CCDC176(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297855|imex:IM-27563-543	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000119636.16(gene)|ensembl:ENST00000394009.5(transcript)|go:""GO:0005930""(axoneme)|go:""GO:0007026""(negative regulation of microtubule depolymerization)|go:""GO:0007288""(sperm axoneme assembly)|go:""GO:0007338""(single fertilization)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0036064""(ciliary basal body)|go:""GO:0036126""(sperm flagellum)|go:""GO:0044458""(motile cilium assembly)|go:""GO:0050821""(protein stabilization)|interpro:IPR032777|mint:Q8ND07|panther:PTHR14845(orthology-group)|refseq:NP_079333.2"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:Vum2/kznYFVHcPAegGT8frMgV7E9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:07CC9A5AD0026D1F|rigid:SOBMS4l9BtthcIKJ6kVOIoZ0QS0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UIF8	uniprotkb:Q5NFP9	intact:EBI-741542|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8|ensembl:ENSP00000376534.2	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297761|imex:IM-27563-9	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_038478.2|refseq:NP_001276904.1|rcsb pdb:4CUP|rcsb pdb:4CUQ|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ7|rcsb pdb:5CQ6|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5E9Y|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBN|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|ensembl:ENSG00000123636.20(gene)|ensembl:ENST00000392783.7(transcript)|rcsb pdb:5PC9|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006338""(chromatin remodeling)|rcsb pdb:5PCA|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|rcsb pdb:5PCB|rcsb pdb:5PCC|go:""GO:0046872""(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PCG|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5PD2|rcsb pdb:5PD3|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PDX|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PEQ|rcsb pdb:5PER|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PFM|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|rcsb pdb:7Q42|rcsb pdb:7WIN|panther:PTHR45915(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:CDF07EDF2D81FFC7|rigid:i+vSBAXxszjFGfDvYeNdT6nJJe4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14977	uniprotkb:Q5NGZ9	intact:EBI-1054824|uniprotkb:A6NCD5|uniprotkb:Q6IBQ7|uniprotkb:Q96D20|ensembl:ENSP00000321507.4|ensembl:ENSP00000337180.5|ensembl:ENSP00000506895.1|ensembl:ENSP00000506898.1|ensembl:ENSP00000507451.1	intact:EBI-22297718|uniprotkb:A0A0G2RPD4	psi-mi:azin1_human(display_long)|uniprotkb:Ornithine decarboxylase antizyme inhibitor(gene name synonym)|uniprotkb:AZIN1(gene name)|psi-mi:AZIN1(display_short)|uniprotkb:OAZI(gene name synonym)|uniprotkb:OAZIN(gene name synonym)	psi-mi:q5ngz9_fratt(display_long)|uniprotkb:FTT_0677c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297728|imex:IM-27563-203	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056962.2|refseq:NP_680479.1|refseq:XP_011515428.1|refseq:XP_011515429.1|ensembl:ENSG00000155096.15(gene)|ensembl:ENST00000337198.10(transcript)|ensembl:ENST00000347770.8(transcript)|ensembl:ENST00000681985.1(transcript)|ensembl:ENST00000682725.1(transcript)|ensembl:ENST00000684566.1(transcript)|go:""GO:0004586""(ornithine decarboxylase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0033387""(putrescine biosynthetic process from arginine, via ornithine)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042978""(ornithine decarboxylase activator activity)|go:""GO:1902269""(positive regulation of polyamine transmembrane transport)|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|interpro:IPR002433(Ornithine decarboxylase)|interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR022643|interpro:IPR022644|interpro:IPR022657|interpro:IPR029066|interpro:IPR031178|mint:O14977|rcsb pdb:4ZGZ|reactome:R-HSA-350562|panther:PTHR11482(orthology-group)"	"go:""GO:0008757""(S-adenosylmethionine-dependent methyltransferase activity)|go:""GO:0032259""(methylation)|interpro:IPR051052|refseq:YP_169693.1|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q5NGZ9|refseq:WP_003020462.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:wopQOhmBCTYUuNN63k1nk+J61i89606	rogid:NsQTuFVA2+HfApHSBfsjyZCn664177416	intact-crc:B74FEE86A77A63A5|rigid:WB59v0Z7Jpz6HdlVgPijPlHP1Pk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5VW32	uniprotkb:Q5NIP8	intact:EBI-6286053|uniprotkb:Q96MG1|uniprotkb:B7Z9G5|ensembl:ENSP00000343742.5	intact:EBI-2796698	psi-mi:brox_human(display_long)|uniprotkb:BROX(gene name)|psi-mi:BROX(display_short)|uniprotkb:BROFTI(gene name synonym)|uniprotkb:C1orf58(gene name synonym)|uniprotkb:BRO1 domain- and CAAX motif-containing protein(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297791|imex:IM-27563-285	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011507516.1|refseq:NP_001275508.1|refseq:NP_001275510.1|refseq:NP_653296.2|refseq:NP_001275509.1|refseq:XP_005273122.2|dip:DIP-59406N|refseq:XP_016855863.1|ensembl:ENSG00000162819.12(gene)|ensembl:ENST00000340934.10(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0007084""(mitotic nuclear membrane reassembly)|go:""GO:0031965""(nuclear membrane)|go:""GO:0070062""(extracellular exosome)|interpro:IPR004328(BRO1)|interpro:IPR038499|interpro:IPR038898|mint:Q5VW32|rcsb pdb:3R9M|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM2|rcsb pdb:3UM3|rcsb pdb:3ZXP|panther:PTHR23032(orthology-group)"	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/28	rogid:YX73MQPZZYz7j3AHQXyItU+bxQ49606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:09E03DAFAB833979|rigid:e0dJi4rFlxL8U/bGHhQ/IiVRE0U	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HB07	uniprotkb:Q5NGE3	intact:EBI-709754|uniprotkb:Q86UA3|intact:EBI-10258793|ensembl:ENSP00000267103.5|ensembl:ENSP00000517432.1	intact:EBI-22297821|uniprotkb:A0A0G2RPC6	psi-mi:myg1_human(display_long)|uniprotkb:MYG1(gene name)|psi-mi:MYG1(display_short)|uniprotkb:C12orf10(gene name synonym)	psi-mi:q5nge3_fratt(display_long)|uniprotkb:FTT_0902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297828|imex:IM-27563-621	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067653.3|ensembl:ENSG00000139637.14(gene)|ensembl:ENSG00000291835.1(gene)|ensembl:ENST00000267103.10(transcript)|ensembl:ENST00000708949.1(transcript)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000959""(mitochondrial RNA metabolic process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006364""(rRNA processing)|go:""GO:0006397""(mRNA processing)|go:""GO:0035641""(locomotory exploration behavior)|interpro:IPR003226(Metal-dependent protein hydrolase)|mint:Q9HB07|panther:PTHR11215(orthology-group)"	refseq:YP_169899.1|mint:Q5NGE3	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:yAZMnr2LGA2TmIXzlFhr5TxXI2I9606	rogid:NCB/Hok6C9lpbhvu2mMcLmSbgZs177416	intact-crc:D1BDCD74C721564E|rigid:dWm4P0JMfGRG62jJRVY/VZq7jo0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P47755	uniprotkb:Q5NES6	intact:EBI-762451|ensembl:ENSP00000354947.2|uniprotkb:B4DG50	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297945|imex:IM-27563-15	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006127.1|ensembl:ENSG00000198898.16(gene)|ensembl:ENST00000361183.8(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|panther:PTHR10653(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/28	rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:845BA129787DBEA4|rigid:Zppg4F2R3RP3WXp9zqjKnW3kyNg	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96L12	uniprotkb:Q5NEC5	intact:EBI-21757403|ensembl:ENSP00000269881.3|uniprotkb:D9N574|uniprotkb:Q96LN3	intact:EBI-22297545	psi-mi:calr3_human(display_long)|uniprotkb:CALR3(gene name)|psi-mi:CALR3(display_short)|uniprotkb:CRT2(gene name synonym)|uniprotkb:Calreticulin-2(gene name synonym)|uniprotkb:Calsperin(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297925|imex:IM-27563-547	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000269058.6(gene)|ensembl:ENST00000269881.8(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006457""(protein folding)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030154""(cell differentiation)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0036503""(ERAD pathway)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:Q96L12|refseq:NP_659483.2|panther:PTHR11073(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/15	rogid:xH1TfFrG8Vb4h7JbW16XuuW8wPg9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:93A15782EF91D783|rigid:jAgpf4mG07q3R06EAnchGsZ89RA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62158	uniprotkb:Q5NGJ5	intact:EBI-397435|uniprotkb:P02593|uniprotkb:Q53S29|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	intact:EBI-22297738|uniprotkb:A0A0G2RPF6	psi-mi:calm_human(display_short)|psi-mi:P62158(display_long)|uniprotkb:CALM1(gene name)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:q5ngj5_fratt(display_long)|uniprotkb:FTT_0842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297915|imex:IM-27563-289	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:1304""(molecule set)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:""GO:0002027""(regulation of heart rate)|go:""GO:0005513""(detection of calcium ion)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0030017""(sarcomere)|go:""GO:0030801""(obsolete positive regulation of cyclic nucleotide metabolic process)|go:""GO:0032516""(obsolete positive regulation of phosphoprotein phosphatase activity)|go:""GO:0035307""(obsolete positive regulation of protein dephosphorylation)|go:""GO:0051343""(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005876""(spindle microtubule)|go:""GO:0000922""(spindle pole)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0006936""(muscle contraction)|go:""GO:0060315""(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0002576""(platelet degranulation)|go:""GO:0060316""(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0050999""(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:""GO:0010801""(negative regulation of peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031954""(positive regulation of protein autophosphorylation)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0000165""(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:5COC|go:""GO:0021762""(substantia nigra development)|go:""GO:0070062""(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|rcsb pdb:4GOW|rcsb pdb:4Q57|go:""GO:0043647""(inositol phosphate metabolic process)|go:""GO:0022400""(regulation of opsin-mediated signaling pathway)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0005576""(extracellular region)|go:""GO:0031997""(obsolete N-terminal myristoylation domain binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0010880""(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031432""(titin binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051592""(response to calcium ion)|go:""GO:0055117""(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:""GO:0005088""|go:""GO:0007223""(Wnt signaling pathway, calcium modulating pathway)|go:""GO:0008440""(inositol-1,4,5-trisphosphate 3-kinase activity)|go:""GO:0015276""(ligand-gated monoatomic ion channel activity)|go:""GO:0005634""(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:4UMO|rcsb pdb:4V0C|go:""GO:0031982""(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|refseq:NP_001292555.1|rcsb pdb:4OVN|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|rcsb pdb:5DBR|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0001975""(response to amphetamine)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0030235""(nitric-oxide synthase regulator activity)|go:""GO:0030426""(growth cone)|go:""GO:0051000""(positive regulation of nitric-oxide synthase activity)|go:""GO:0051412""(response to corticosterone)|go:""GO:1901841""(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:""GO:0032991""(protein-containing complex)|go:""GO:0006479""(protein methylation)|go:""GO:0014069""(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0043388""(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:""GO:0034704""(calcium channel complex)|go:""GO:0010856""(adenylate cyclase activator activity)|go:""GO:0051186""(obsolete cofactor metabolic process)|go:""GO:0075206""(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:""GO:0060314""(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:""GO:1902494""(catalytic complex)|go:""GO:0043234""|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0030819""(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:""GO:0019722""(calcium-mediated signaling)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:""GO:0005623""(obsolete cell)|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|rcsb pdb:6HR1|rcsb pdb:6OS4|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0016032""(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O"	"go:""GO:0009279""(cell outer membrane)|interpro:IPR050330|refseq:WP_003020808.1|refseq:YP_169847.1|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|mint:Q5NGJ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/25	-	rogid:/Dq7r5H2A4RbaDlrrHYQHMOGtbc177416	intact-crc:DBA58B63A0C623C3	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13987	uniprotkb:Q5NEC5	intact:EBI-297972|ensembl:ENSP00000340210.3|ensembl:ENSP00000379191.3|ensembl:ENSP00000403511.2|ensembl:ENSP00000404822.2|ensembl:ENSP00000410182.2|ensembl:ENSP00000432942.1|ensembl:ENSP00000494884.1|ensembl:ENSP00000498448.1|ensembl:ENSP00000498879.1|uniprotkb:E9PR17	intact:EBI-22297545	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297975|imex:IM-27563-111	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:169464""|ensembl:ENSG00000085063.18(gene)|ensembl:ENST00000351554.8(transcript)|ensembl:ENST00000395850.9(transcript)|ensembl:ENST00000415002.7(transcript)|ensembl:ENST00000437761.6(transcript)|ensembl:ENST00000445143.6(transcript)|ensembl:ENST00000527577.5(transcript)|ensembl:ENST00000642928.2(transcript)|ensembl:ENST00000651785.1(transcript)|ensembl:ENST00000652678.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001848""(complement binding)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0005615""(extracellular space)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007596""(blood coagulation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030133""(transport vesicle)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0031982""(vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR045860|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|rcsb pdb:8B0F|rcsb pdb:8B0G|rcsb pdb:8B0H|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|panther:PTHR10036(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:55B18115DA4A0B6B|rigid:Ef7ELB4zcaAD17t6vBml89tf0+4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TAL5	uniprotkb:Q5NEC5	intact:EBI-10694291|ensembl:ENSP00000288462.4|ensembl:ENSP00000363280.1	intact:EBI-22297545	psi-mi:ci043_human(display_long)|uniprotkb:C9orf43(gene name)|psi-mi:C9orf43(display_short)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297885|imex:IM-27563-623	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001265558.1|refseq:NP_689999.1|ensembl:ENSG00000157653.12(gene)|ensembl:ENST00000288462.4(transcript)|ensembl:ENST00000374165.6(transcript)|interpro:IPR029134|mint:Q8TAL5|panther:PTHR36130(orthology-group)	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:LGnLEmC1sPfnq+qr2b3M7cEccek9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:780C8737B88C033C|rigid:dvoNPVrMXN8Tg9ek8/bTJftxGTQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y530	uniprotkb:Q5NG28	intact:EBI-8502288|uniprotkb:A6NEK4|uniprotkb:Q96F23|intact:MINT-6946088|uniprotkb:A8K4H4|ensembl:ENSP00000416829.2|ensembl:ENSP00000420193.1|ensembl:ENSP00000420484.1|ensembl:ENSP00000420601.1	intact:EBI-2802768|uniprotkb:A0A0G2RPI9	psi-mi:oard1_human(display_long)|uniprotkb:OARD1(gene name)|psi-mi:OARD1(display_short)|uniprotkb:C6orf130(gene name synonym)|uniprotkb:O-acetyl-ADP-ribose deacetylase 1(gene name synonym)|uniprotkb:TARG1(gene name synonym)|uniprotkb:Terminal ADP-ribose protein glycohydrolase 1(gene name synonym)|uniprotkb:[Protein ADP-ribosylglutamate] hydrolase OARD1(gene name synonym)	psi-mi:q5ng28_fratt(display_long)|uniprotkb:dacD(gene name)|psi-mi:dacD(display_short)|uniprotkb:FTT_1029(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297875|imex:IM-27563-205	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_659500.1|refseq:NP_001316613.1|refseq:NP_001316614.1|refseq:NP_001316615.1|refseq:NP_001316617.1|ensembl:ENSG00000124596.17(gene)|ensembl:ENST00000424266.7(transcript)|ensembl:ENST00000463088.5(transcript)|ensembl:ENST00000468811.5(transcript)|ensembl:ENST00000479950.5(transcript)|go:""GO:0001883""(purine nucleoside binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006974""(DNA damage response)|go:""GO:0042278""(purine nucleoside metabolic process)|go:""GO:0047407""(ADP-ribosyl-[dinitrogen reductase] hydrolase activity)|go:""GO:0051725""(protein de-ADP-ribosylation)|go:""GO:0061463""(O-acetyl-ADP-ribose deacetylase activity)|go:""GO:0090734""(site of DNA damage)|go:""GO:0140291""(peptidyl-glutamate ADP-deribosylation)|go:""GO:0140293""(ADP-ribosylglutamate hydrolase activity)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR043472|interpro:IPR050892|mint:Q9Y530|rcsb pdb:2EEE|rcsb pdb:2L8R|rcsb pdb:2LGR|rcsb pdb:4J5Q|rcsb pdb:4J5R|rcsb pdb:4J5S|panther:PTHR12521(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015956(Penicillin-binding protein-associated)|interpro:IPR018044|interpro:IPR012907(Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal)|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:YP_170014.1|refseq:WP_003021136.1|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|rcsb pdb:6OSU|mint:Q5NG28|interpro:IPR037167"	-	comment:mint|comment:homomint	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:gpT7Rwra3qEVjLpdSYrT9dCXBRI9606	rogid:EYTPcD8JUkej9Gvps0ogQD5aQ1c177416	intact-crc:46752CB17038F5B2|rigid:nCSx2/39+Hbv8SJMuy7M8X3IbdU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HB71	uniprotkb:Q5NHH2	intact:EBI-1047302|uniprotkb:O60666|uniprotkb:B2ZWH2|uniprotkb:Q5R371|uniprotkb:B3KSF1|uniprotkb:Q5R370|intact:EBI-21351010|ensembl:ENSP00000356652.2	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:cybp_human(display_long)|uniprotkb:Siah-interacting protein(gene name synonym)|uniprotkb:S100A6-binding protein(gene name synonym)|uniprotkb:CACYBP(gene name)|psi-mi:CACYBP(display_short)|uniprotkb:S100A6BP(gene name synonym)|uniprotkb:SIP(gene name synonym)|uniprotkb:PNAS-107(orf name)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297905|imex:IM-27563-545	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001007215.1|refseq:NP_055227.1|refseq:XP_016856535.1|ensembl:ENSG00000116161.18(gene)|ensembl:ENST00000367679.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007507""(heart development)|go:""GO:0015631""(tubulin binding)|go:""GO:0030877""(beta-catenin destruction complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044548""(S100 protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR015120(Siah interacting protein, N terminal)|interpro:IPR037201|interpro:IPR037893|interpro:IPR052289|mint:Q9HB71|rcsb pdb:1X5M|rcsb pdb:2A25|rcsb pdb:2A26|panther:PTHR13164(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:mvv1o19mLHBS3FDnATyOFsDoZvk9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:8E23F22256AAC1E5|rigid:yzfWtvlhMUYAyxnOOj93izG1vDY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75952	uniprotkb:Q5NHT8	intact:EBI-10898454|uniprotkb:B2R857|uniprotkb:Q8WXW5|uniprotkb:Q9HAY3|uniprotkb:Q9HAY4|uniprotkb:Q9HAY5|uniprotkb:Q9HCY9|ensembl:ENSP00000431142.3|ensembl:ENSP00000432870.1|ensembl:ENSP00000483621.1	intact:EBI-2806309	psi-mi:cabyr_human(display_long)|uniprotkb:CABYR(gene name)|psi-mi:CABYR(display_short)|uniprotkb:CBP86(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Calcium-binding protein 86(gene name synonym)|uniprotkb:Cancer/testis antigen 88(gene name synonym)|uniprotkb:Fibrousheathin II(gene name synonym)|uniprotkb:Fibrousheathin-2(gene name synonym)|uniprotkb:Testis-specific calcium-binding protein CBP86(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297895|imex:IM-27563-207	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036321.2|refseq:NP_619584.1|refseq:NP_619585.1|refseq:NP_722452.1|refseq:NP_722453.1|refseq:NP_722454.1|refseq:XP_016881195.1|ensembl:ENSG00000154040.21(gene)|ensembl:ENST00000463087.5(transcript)|ensembl:ENST00000486759.6(transcript)|ensembl:ENST00000621648.4(transcript)|go:""GO:0003351""(epithelial cilium movement involved in extracellular fluid movement)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0031514""(motile cilium)|go:""GO:0035686""(sperm fibrous sheath)|go:""GO:0048240""(sperm capacitation)|go:""GO:0097228""(sperm principal piece)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR038848|interpro:IPR047579|mint:O75952|panther:PTHR15494(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:64WTKl4YcRJZDlxroCpoHRKmXDo9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:C7D0631462B0176B|rigid:8E4vp0IjL6ZWwotcP3Cbn+sdxc8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01518	uniprotkb:Q5NEC5	intact:EBI-2808398|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1|ensembl:ENSP00000361878.2|ensembl:ENSP00000361883.3|ensembl:ENSP00000361891.3	intact:EBI-22297545	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297935|imex:IM-27563-109	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_005270425.1|ensembl:ENSG00000131236.18(gene)|ensembl:ENST00000372792.7(transcript)|ensembl:ENST00000372797.7(transcript)|ensembl:ENST00000372805.8(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001667""(ameboidal-type cell migration)|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007165""(signal transduction)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0019933""(cAMP-mediated signaling)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098885""(modification of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR036222|interpro:IPR036223|interpro:IPR053950|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|dip:DIP-62063N|panther:PTHR10652(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	crc64:7789D1FAC0D1AB7B	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/28	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:C269148777757804|rigid:VutkyYpu4kIc4W8VMatmghLvDgA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9GZT6	uniprotkb:Q5NHH2	intact:EBI-713148|uniprotkb:Q3B781|uniprotkb:Q9GZU6|uniprotkb:A8K8I4|uniprotkb:B4E3L2|ensembl:ENSP00000434724.1|uniprotkb:B3KP87	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:cc90b_human(display_long)|uniprotkb:CUA003(orf name)|uniprotkb:CCDC90B(gene name)|psi-mi:CCDC90B(display_short)|uniprotkb:MDS011(orf name)|uniprotkb:MDS025(orf name)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297955|imex:IM-27563-463	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273045.1|refseq:NP_001273046.1|refseq:NP_001273047.1|refseq:NP_001273048.1|refseq:NP_001273049.1|refseq:NP_068597.2|ensembl:ENSG00000137500.10(gene)|ensembl:ENST00000529689.6(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0031966""(mitochondrial membrane)|interpro:IPR024461|mint:Q9GZT6|rcsb pdb:6H9M|refseq:XP_016873593.1|refseq:XP_005274216.1|panther:PTHR14360(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:eFdcuPTHBcuVWQ1tEdAnIKN9IhI9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:517FB8232A8A3DE2|rigid:VD0f40+24NJhF/2KBHv1Z2uFT2U	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50990	uniprotkb:Q5NFP9	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788.4|ensembl:ENSP00000517017.1	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:tcpq_human(display_long)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297965|imex:IM-27563-549	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11353(orthology-group)|refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|rcsb pdb:8SHE|ensembl:ENSG00000156261.13(gene)|ensembl:ENSG00000291533.1(gene)|ensembl:ENST00000286788.9(transcript)|ensembl:ENST00000707884.1(transcript)|go:""GO:0002199""(zona pellucida receptor complex)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005832""(chaperonin-containing T-complex)|go:""GO:0005874""(microtubule)|go:""GO:0005929""(cilium)|go:""GO:0006457""(protein folding)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0016887""(ATP hydrolysis activity)|rcsb pdb:8SHD|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044297""(cell body)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045296""(cadherin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051086""(chaperone mediated protein folding independent of cofactor)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1904874""(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|rcsb pdb:7NVL|rcsb pdb:7NVM|rcsb pdb:7NVN|rcsb pdb:7NVO|rcsb pdb:7TRG|rcsb pdb:7TTN|rcsb pdb:7TTT|rcsb pdb:7TUB|rcsb pdb:7WU7|rcsb pdb:7WZ3|rcsb pdb:7X0A|rcsb pdb:7X0S|rcsb pdb:7X0V|rcsb pdb:7X3J|rcsb pdb:7X3U|rcsb pdb:7X6Q|rcsb pdb:7X7Y|rcsb pdb:8HKI|rcsb pdb:8I1U|rcsb pdb:8I9U|rcsb pdb:8IB8|rcsb pdb:8SFE|rcsb pdb:8SFF|rcsb pdb:8SG8|rcsb pdb:8SG9|rcsb pdb:8SGC|rcsb pdb:8SGL|rcsb pdb:8SGQ|rcsb pdb:8SH9|rcsb pdb:8SHA|rcsb pdb:8SHF|rcsb pdb:8SHG|rcsb pdb:8SHL|rcsb pdb:8SHN|rcsb pdb:8SHO|rcsb pdb:8SHP|rcsb pdb:8SHQ|rcsb pdb:8SHT|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6798695|reactome:R-HSA-6814122|dip:DIP-38124N"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/26	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:E9FFCE52D71818BE|rigid:GdCN4gui/tIdqoT5uRO8IUCS4ZQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q58WW2	uniprotkb:Q5NEC5	intact:EBI-2559044|ensembl:ENSP00000311949.6|uniprotkb:Q8TB19|uniprotkb:Q8IXH3|uniprotkb:A2A295|uniprotkb:Q7L8I0|uniprotkb:B4DNB8	intact:EBI-22297545	psi-mi:dcaf6_human(display_long)|uniprotkb:DCAF6(gene name)|psi-mi:DCAF6(display_short)|uniprotkb:IQWD1(gene name synonym)|uniprotkb:Nuclear receptor interaction protein(gene name synonym)|uniprotkb:IQ motif and WD repeat-containing protein 1(gene name synonym)|uniprotkb:Androgen receptor complex-associated protein(gene name synonym)|uniprotkb:MSTP055(orf name)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298035|imex:IM-27563-467	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143164.16(gene)|ensembl:ENST00000312263.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR045151|mint:Q58WW2|rcsb pdb:3I7O|reactome:R-HSA-8951664|refseq:NP_001017977.1|refseq:NP_001185885.1|refseq:NP_001185886.1|refseq:NP_060912.2|dip:DIP-44678N|panther:PTHR15574(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/25	rogid:1CtoPWPj6fdryvDlC46pXiUguDc9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:A2156898BEEC363B|rigid:4xn0KqLRXkiRCbXFRlGcnC76vK8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NE35	uniprotkb:Q5NHH2	intact:EBI-8596191|ensembl:ENSP00000265997.4|ensembl:ENSP00000482128.1|uniprotkb:Q9Y2E9|uniprotkb:Q9NQJ7|uniprotkb:Q5T389|intact:UNK-5523090	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:cpeb3_human(display_long)|uniprotkb:CPEB3(gene name)|psi-mi:CPEB3(display_short)|uniprotkb:KIAA0940(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298015|imex:IM-27563-17	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000107864.15(gene)|ensembl:ENST00000265997.5(transcript)|ensembl:ENST00000614585.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000900""(mRNA regulatory element binding translation repressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007616""(long-term memory)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0014069""(postsynaptic density)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030014""(CCR4-NOT complex)|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043022""(ribosome binding)|go:""GO:0045202""(synapse)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0060998""(regulation of dendritic spine development)|go:""GO:0060999""(positive regulation of dendritic spine development)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0097440""(apical dendrite)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1900248""(negative regulation of cytoplasmic translational elongation)|go:""GO:2000766""(negative regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032296|interpro:IPR034819|interpro:IPR035979|interpro:IPR038446|mint:Q8NE35|rcsb pdb:2DNL|rcsb pdb:2RUG|rcsb pdb:7N2E|rcsb pdb:7N2F|rcsb pdb:7N2G|rcsb pdb:8SPA|refseq:NP_055727.3|refseq:NP_001171608.1|refseq:XP_005269687.1|panther:PTHR12566(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	comment:mint	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:WzbauahDDjrcRmf9PCoBmlbSyyI9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:145DEAA82E4849F5|rigid:k3au+Xh98A9oaGzczk0wOpTt15E	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13206	uniprotkb:Q5NHT8	intact:EBI-2514399|uniprotkb:Q5BJD8|uniprotkb:B2RCQ3|ensembl:ENSP00000314348.3	intact:EBI-2806309	psi-mi:ddx10_human(display_long)|uniprotkb:DDX10(gene name)|psi-mi:DDX10(display_short)|uniprotkb:DEAD box protein 10(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298055|imex:IM-27563-121	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000178105.12(gene)|ensembl:ENST00000322536.8(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0006364""(rRNA processing)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0097065""(anterior head development)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417|mint:Q13206|rcsb pdb:2PL3|refseq:NP_004389.2|panther:PTHR24031(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:MMAbABrYQHlYDyPsagT7oY92Z3M9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:6535FCA8DEDEA3F3|rigid:znqX4X60aLMXQao0cY6SNzgmj+k	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H819	uniprotkb:Q5NG28	intact:EBI-21505462|ensembl:ENSP00000302843.5	intact:EBI-2802768|uniprotkb:A0A0G2RPI9	psi-mi:djc18_human(display_long)|uniprotkb:DNAJC18(gene name)|psi-mi:DNAJC18(display_short)	psi-mi:q5ng28_fratt(display_long)|uniprotkb:dacD(gene name)|psi-mi:dacD(display_short)|uniprotkb:FTT_1029(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298105|imex:IM-27563-471	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000170464.10(gene)|ensembl:ENST00000302060.10(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0071218""(cellular response to misfolded protein)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR015399(Protein of unknown function DUF1977, DnaJ-like)|interpro:IPR018253|interpro:IPR036869|interpro:IPR051100|mint:Q9H819|refseq:NP_689899.1|panther:PTHR43908(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015956(Penicillin-binding protein-associated)|interpro:IPR018044|interpro:IPR012907(Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal)|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:YP_170014.1|refseq:WP_003021136.1|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|rcsb pdb:6OSU|mint:Q5NG28|interpro:IPR037167"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:i7Ht6oVsOxILPjRRRkiY0Y/g7Fo9606	rogid:EYTPcD8JUkej9Gvps0ogQD5aQ1c177416	intact-crc:B5F90D43E5CD9651|rigid:TK4xt7Fv2mVi7+dUP/abQrESruU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UDY4	uniprotkb:Q5NFP9	intact:EBI-356960|uniprotkb:Q13431|uniprotkb:B2R824|ensembl:ENSP00000359799.5	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:dnjb4_human(display_long)|uniprotkb:DNAJB4(gene name)|psi-mi:DNAJB4(display_short)|uniprotkb:DNAJW(gene name synonym)|uniprotkb:HLJ1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1 homolog(gene name synonym)|uniprotkb:Human liver DnaJ-like protein(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298095|imex:IM-27563-551	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_008965.2|ensembl:ENSG00000162616.9(gene)|ensembl:ENST00000370763.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001671""(ATPase activator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0009408""(response to heat)|go:""GO:0030018""(Z disc)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|interpro:IPR051339|mint:Q9UDY4|refseq:NP_001304028.1|refseq:NP_001304029.1|refseq:NP_001304030.1|refseq:NP_001304031.1|refseq:NP_001304032.1|panther:PTHR24078(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:gN0zBtJQiTN+YYSAtMk1mddNWLU9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:7D47209084577AF1|rigid:qNtRWj/4vKtjb3CY+KmlnJeRkrM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q03188	uniprotkb:Q5NEM9	intact:EBI-295799|uniprotkb:Q9P0M5|ensembl:ENSP00000273853.6|uniprotkb:Q8IW27|uniprotkb:Q6PIR0	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297995|imex:IM-27563-627	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001803.2|ensembl:ENSG00000145241.11(gene)|ensembl:ENST00000273853.11(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0000779""(condensed chromosome, centromeric region)|go:""GO:0000939""(inner kinetochore)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005829""(cytosol)|go:""GO:0007059""(chromosome segregation)|go:""GO:0016604""(nuclear body)|go:""GO:0019237""(centromeric DNA binding)|go:""GO:0030496""(midbody)|go:""GO:0042802""(identical protein binding)|go:""GO:0051301""(cell division)|go:""GO:0051315""(attachment of mitotic spindle microtubules to kinetochore)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0051455""(spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:7PII|rcsb pdb:7QOO|rcsb pdb:7R5R|rcsb pdb:7XHN|rcsb pdb:7XHO|rcsb pdb:7YWX|rcsb pdb:7YYH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|panther:PTHR16684(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:A74E200C3D0EAEEE|rigid:wyWasLwJxOwC7JEr/WXyaBdLmUM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q03188	uniprotkb:Q5NFP9	intact:EBI-295799|uniprotkb:Q9P0M5|ensembl:ENSP00000273853.6|uniprotkb:Q8IW27|uniprotkb:Q6PIR0	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22297985|imex:IM-27563-625	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001803.2|ensembl:ENSG00000145241.11(gene)|ensembl:ENST00000273853.11(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0000779""(condensed chromosome, centromeric region)|go:""GO:0000939""(inner kinetochore)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005829""(cytosol)|go:""GO:0007059""(chromosome segregation)|go:""GO:0016604""(nuclear body)|go:""GO:0019237""(centromeric DNA binding)|go:""GO:0030496""(midbody)|go:""GO:0042802""(identical protein binding)|go:""GO:0051301""(cell division)|go:""GO:0051315""(attachment of mitotic spindle microtubules to kinetochore)|go:""GO:0051382""(kinetochore assembly)|go:""GO:0051455""(spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:7PII|rcsb pdb:7QOO|rcsb pdb:7R5R|rcsb pdb:7XHN|rcsb pdb:7XHO|rcsb pdb:7YWX|rcsb pdb:7YYH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|panther:PTHR16684(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:926DBA770682F281|rigid:ZvSw3YPQQqIZrCvTvHwTx+GvWxQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35638	uniprotkb:Q5NGJ5	intact:EBI-742651|uniprotkb:F8VS99|ensembl:ENSP00000340671.3|ensembl:ENSP00000447188.1|ensembl:ENSP00000494844.1	intact:EBI-22297738|uniprotkb:A0A0G2RPF6	psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)	psi-mi:q5ngj5_fratt(display_long)|uniprotkb:FTT_0842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298045|imex:IM-27563-291	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-41589N|ensembl:ENSG00000175197.13(gene)|ensembl:ENST00000346473.8(transcript)|ensembl:ENST00000547303.5(transcript)|ensembl:ENST00000623876.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001955""(blood vessel maturation)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006974""(DNA damage response)|go:""GO:0006983""(ER overload response)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008140""(cAMP response element binding protein binding)|go:""GO:0009611""(response to wounding)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0010467""(gene expression)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032700""(negative regulation of interleukin-17 production)|go:""GO:0032713""(negative regulation of interleukin-4 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036119""(response to platelet-derived growth factor)|go:""GO:0036488""(CHOP-C/EBP complex)|go:""GO:0036499""(PERK-mediated unfolded protein response)|go:""GO:0036500""(ATF6-mediated unfolded protein response)|go:""GO:0042594""(response to starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043522""(leucine zipper domain binding)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060840""(artery development)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0072655""(establishment of protein localization to mitochondrion)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140416""(transcription regulator inhibitor activity)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:0140468""(HRI-mediated signaling)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1904738""(vascular associated smooth muscle cell migration)|go:""GO:1990442""(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:""GO:1990617""(CHOP-ATF4 complex)|go:""GO:1990622""(CHOP-ATF3 complex)|go:""GO:1990874""(vascular associated smooth muscle cell proliferation)|go:""GO:2000016""(negative regulation of determination of dorsal identity)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|refseq:NP_001181986.1|refseq:NP_004074.2|efo:""Orphanet:99967""|panther:PTHR16833(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|interpro:IPR050330|refseq:WP_003020808.1|refseq:YP_169847.1|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|mint:Q5NGJ5"	-	crc64:31905293FB1FBBE2	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606	rogid:/Dq7r5H2A4RbaDlrrHYQHMOGtbc177416	intact-crc:500ED8014FADB381|rigid:M6NI4d8tUSflJREvjDFhMmUFvAs	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NX08	uniprotkb:Q5NES6	intact:EBI-725694|uniprotkb:Q8WUR4|uniprotkb:Q9HC15|ensembl:ENSP00000370984.4	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:comd8_human(display_long)|uniprotkb:COMMD8(gene name)|psi-mi:COMMD8(display_short)|uniprotkb:MDS022(orf name)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298005|imex:IM-27563-465	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060315.1|refseq:NP_001316597.1|ensembl:ENSG00000169019.11(gene)|ensembl:ENST00000381571.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0051059""(NF-kappaB binding)|interpro:IPR017920|interpro:IPR047155|interpro:IPR047235|interpro:IPR055184|mint:Q9NX08|rcsb pdb:8F2R|rcsb pdb:8F2U|rcsb pdb:8P0W|reactome:R-HSA-8951664|panther:PTHR16231(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:m3HKrdrtTRNJyCfMBLOZCaZRexg9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:B47AA374D3E3837F|rigid:o6nJ6WdYZDZfIMvGKFwPgz4LYLM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NS37	uniprotkb:Q5NIP8	intact:EBI-632965|uniprotkb:Q52LT3|uniprotkb:B2R8Q9|uniprotkb:Q0P5U9|ensembl:ENSP00000433459.1|ensembl:ENSP00000434281.1	intact:EBI-2796698	psi-mi:zhang_human(display_long)|uniprotkb:Host cell factor-binding transcription factor Zhangfei(gene name synonym)|uniprotkb:CREBZF(gene name)|psi-mi:CREBZF(display_short)|uniprotkb:ZF(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298025|imex:IM-27563-113	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001034707.1|refseq:XP_016873577.1|refseq:XP_016873578.1|refseq:XP_016873579.1|refseq:XP_016873580.1|refseq:XP_016873581.1|ensembl:ENSG00000137504.16(gene)|ensembl:ENST00000490820.2(transcript)|ensembl:ENST00000527447.2(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0009615""(response to virus)|go:""GO:0036500""(ATF6-mediated unfolded protein response)|go:""GO:0042802""(identical protein binding)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051090""(regulation of DNA-binding transcription factor activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140467""(integrated stress response signaling)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR046347|mint:Q9NS37|refseq:XP_011543497.1|dip:DIP-33934N"	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/12/11	rogid:f4aOJ/8bwzLv6oFRz6dERW2dUIA9606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:42CF0C7BFF35AC72|rigid:LFbN6SEJNVz2GNUwGwSn3NRAYR4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BTC0	uniprotkb:Q5NES6	intact:EBI-739985|uniprotkb:O15043|uniprotkb:A8MY65|uniprotkb:Q3ZTL7|uniprotkb:Q3ZTL8|uniprotkb:Q4VXS1|uniprotkb:Q4VXS2|uniprotkb:Q4VXV8|uniprotkb:Q96D72|uniprotkb:Q9BQW0|uniprotkb:Q9BW03|uniprotkb:Q9H4G6|uniprotkb:Q9H4G7|uniprotkb:Q9NTU8|uniprotkb:Q9NUM8|uniprotkb:Q9UFB6|uniprotkb:B9EH82|uniprotkb:Q4VXV9|uniprotkb:E1P5I1|ensembl:ENSP00000266070.4|ensembl:ENSP00000378752.1|intact:EBI-28975591	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:dido1_human(display_long)|uniprotkb:DIDO1(gene name)|psi-mi:DIDO1(display_short)|uniprotkb:Death-associated transcription factor 1(gene name synonym)|uniprotkb:C20orf158(gene name synonym)|uniprotkb:DATF1(gene name synonym)|uniprotkb:KIAA0333(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298065|imex:IM-27563-383	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001180298.1|refseq:NP_001180299.1|refseq:NP_071388.2|refseq:NP_149072.2|refseq:NP_542986.1|refseq:NP_542987.2|refseq:XP_011526811.1|ensembl:ENSG00000101191.17(gene)|ensembl:ENST00000266070.8(transcript)|ensembl:ENST00000395343.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0097190""(apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR033082|interpro:IPR036575|mint:Q9BTC0|rcsb pdb:2M3H|rcsb pdb:4L7X|reactome:R-HSA-1221632|panther:PTHR11477(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:xtp4cq/633PxqppXYlVvameuI7M9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:38315720F34028FA|rigid:2Fpl/Af+nsO7v8uJzn1uxgKFUqg	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UI17	uniprotkb:Q5NEC5	intact:EBI-20890502|uniprotkb:B2RBN0|uniprotkb:B4E1J9|ensembl:ENSP00000255189.3	intact:EBI-22297545	psi-mi:m2gd_human(display_long)|uniprotkb:ME2GLYDH(gene name synonym)|uniprotkb:DMGDH(gene name)|psi-mi:DMGDH(display_short)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298075|imex:IM-27563-469	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:243343""|panther:PTHR13847(orthology-group)|ensembl:ENSG00000132837.15(gene)|ensembl:ENST00000255189.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006579""(amino-acid betaine catabolic process)|go:""GO:0009055""(electron transfer activity)|go:""GO:0019695""(choline metabolic process)|go:""GO:0042426""(choline catabolic process)|go:""GO:0047865""(dimethylglycine dehydrogenase activity)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR006222(Glycine cleavage T-protein, N-terminal)|interpro:IPR013977(Glycine cleavage T-protein, C-terminal barrel)|interpro:IPR027266|interpro:IPR028896|interpro:IPR029043|interpro:IPR032503|interpro:IPR036188|mint:Q9UI17|rcsb pdb:5L46|reactome:R-HSA-6798163|refseq:NP_037523.2"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:6g7Vyu/wQTekdCGtobtb9E9olpM9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:55DCDE7E5B735557|rigid:POTmsQKwxLgNmA3/k4KZq2aLJfc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UBS4	uniprotkb:Q5NEM9	intact:EBI-713113|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6|ensembl:ENSP00000265028.3|ensembl:ENSP00000414398.1	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298085|imex:IM-27563-209	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090520.12(gene)|ensembl:ENST00000265028.8(transcript)|ensembl:ENST00000439351.5(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006457""(protein folding)|go:""GO:0016020""(membrane)|go:""GO:0016556""(mRNA modification)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051604""(protein maturation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0101031""(protein folding chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|interpro:IPR051736|mint:Q9UBS4|reactome:R-HSA-381038|refseq:NP_057390.1|efo:""Orphanet:730""|dip:DIP-29678N|panther:PTHR44298(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/01	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:94BB339AC7F37BF9|rigid:xER+chvdxpwiLcZ2rtzpbyBxAo4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00488	uniprotkb:Q5NFP9	intact:EBI-2565863|uniprotkb:Q59HA7|uniprotkb:Q8N6X2|uniprotkb:Q96P24|uniprotkb:Q9BX29|ensembl:ENSP00000264870.3	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:f13a_human(display_long)|uniprotkb:F13A1(gene name)|psi-mi:F13A1(display_short)|uniprotkb:F13A(gene name synonym)|uniprotkb:Protein-glutamine gamma-glutamyltransferase A chain(gene name synonym)|uniprotkb:Transglutaminase A chain(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298220|imex:IM-27563-385	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000124491.16(gene)|ensembl:ENST00000264870.8(transcript)|go:""GO:0003810""(protein-glutamine gamma-glutamyltransferase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0007596""(blood coagulation)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0046872""(metal ion binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0072378""(blood coagulation, fibrin clot formation)|go:""GO:0072562""(blood microparticle)|go:""GO:1990234""(transferase complex)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|interpro:IPR050779|mint:P00488|rcsb pdb:1EVU|rcsb pdb:1EX0|rcsb pdb:1F13|rcsb pdb:1FIE|rcsb pdb:1GGT|rcsb pdb:1GGU|rcsb pdb:1GGY|rcsb pdb:1QRK|rcsb pdb:4KTY|rcsb pdb:5MHL|rcsb pdb:5MHM|rcsb pdb:5MHN|rcsb pdb:5MHO|rcsb pdb:8CMT|rcsb pdb:8CMU|reactome:R-HSA-114608|reactome:R-HSA-140875|reactome:R-HSA-6785807|refseq:NP_000120.2|dip:DIP-377N|efo:""Orphanet:331""|panther:PTHR11590(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:IWmnuQaMKNBRiGMEZboCITlR4Oc9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:98360042A092E383|rigid:axoKt4PzECS288r4ahCy3IY5bQg	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P32519	uniprotkb:Q5NGJ5	intact:EBI-765526|uniprotkb:Q9UDE1|uniprotkb:Q8N6F6|ensembl:ENSP00000239882.3|uniprotkb:B4E2I5|uniprotkb:E9PDQ9	intact:EBI-22297738|uniprotkb:A0A0G2RPF6	psi-mi:elf1_human(display_long)|uniprotkb:E74-like factor 1(gene name synonym)|uniprotkb:ELF1(gene name)|psi-mi:ELF1(display_short)	psi-mi:q5ngj5_fratt(display_long)|uniprotkb:FTT_0842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298170|imex:IM-27563-555	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_758961.1|ensembl:ENSG00000120690.17(gene)|ensembl:ENST00000239882.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR022084|interpro:IPR036388|interpro:IPR036390|interpro:IPR046328|mint:P32519|rcsb pdb:8BZM|reactome:R-HSA-8939245|reactome:R-HSA-8939247|refseq:NP_001138825.1|refseq:XP_005266333.1|refseq:XP_005266334.1|refseq:XP_011533252.1|refseq:XP_016875898.1|refseq:XP_016875899.1|refseq:XP_016875900.1|refseq:XP_016875901.1|refseq:XP_016875902.1|dip:DIP-185N|panther:PTHR11849(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|interpro:IPR050330|refseq:WP_003020808.1|refseq:YP_169847.1|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|mint:Q5NGJ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:bkNv2VvMBvrmLtvw8qhFrj9Zgqg9606	rogid:/Dq7r5H2A4RbaDlrrHYQHMOGtbc177416	intact-crc:4FD67B466858BC5D|rigid:lwjDcTUIwp8K8gOc16IRFvyQ8zU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A4FU69	uniprotkb:Q5NEC5	intact:EBI-11722294|uniprotkb:B2RPN0|uniprotkb:B4DS75|uniprotkb:B4DZR5|uniprotkb:F5GYL2|uniprotkb:Q0VD68|uniprotkb:Q6ZRM6|uniprotkb:Q8NDG9|ensembl:ENSP00000378312.3	intact:EBI-22297545	psi-mi:efcb5_human(display_long)|uniprotkb:EFCAB5(gene name)|psi-mi:EFCAB5(display_short)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298130|imex:IM-27563-553	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138525.1|refseq:NP_940931.2|ensembl:ENSG00000176927.16(gene)|ensembl:ENST00000394835.8(transcript)|go:""GO:0005509""(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018247|interpro:IPR029016|mint:A4FU69|panther:PTHR46788(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:56kp/VGpt4CcyoIMa3iRiRLGYNM9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:0857131F4FA0CF05|rigid:cGgunYa7YMI9xWaw55y6a9/bWyc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16422	uniprotkb:Q5NFP9	intact:EBI-1171184|uniprotkb:P18180|uniprotkb:Q96C47|uniprotkb:Q6FG26|uniprotkb:Q6FG49|uniprotkb:Q9UCD0|ensembl:ENSP00000263735.4	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:epcam_human(display_long)|uniprotkb:EPCAM(gene name)|psi-mi:EPCAM(display_short)|uniprotkb:GA733-2(gene name synonym)|uniprotkb:M1S2(gene name synonym)|uniprotkb:TROP1(gene name synonym)|uniprotkb:Major gastrointestinal tumor-associated protein GA733-2(gene name synonym)|uniprotkb:Epithelial cell surface antigen(gene name synonym)|uniprotkb:Epithelial glycoprotein(gene name synonym)|uniprotkb:Adenocarcinoma-associated antigen(gene name synonym)|uniprotkb:KSA(gene name synonym)|uniprotkb:KS 1/4 antigen(gene name synonym)|uniprotkb:Cell surface glycoprotein Trop-1(gene name synonym)|uniprotkb:M4S1(gene name synonym)|uniprotkb:MIC18(gene name synonym)|uniprotkb:TACSTD1(gene name synonym)|uniprotkb:Tumor-associated calcium signal transducer 1(gene name synonym)|uniprotkb:Epithelial glycoprotein 314(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298180|imex:IM-27563-223	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR14168(orthology-group)|ensembl:ENSG00000119888.11(gene)|ensembl:ENST00000263735.9(transcript)|go:""GO:0001657""(ureteric bud development)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0023019""(signal transduction involved in regulation of gene expression)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048863""(stem cell differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000648""(positive regulation of stem cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|rcsb pdb:4MZV|interpro:IPR036857|interpro:IPR041630|interpro:IPR043406|interpro:IPR049420|mint:P16422|rcsb pdb:6I07|reactome:R-HSA-202733|refseq:NP_002345.2|efo:""Orphanet:144""|efo:""Orphanet:92050"""	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:mzYNoxHCDJuzMM5HkW5FIOaxm1w9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:A0AE062DAF3AFE82|rigid:B2aZJkZc5C19NIKyOk5s+M3pxhk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60739	uniprotkb:Q5NEC5	intact:EBI-1043343|uniprotkb:Q9UQF8|ensembl:ENSP00000232905.3	intact:EBI-22297545	psi-mi:eif1b_human(display_long)|uniprotkb:Protein translation factor SUI1 homolog GC20(gene name synonym)|uniprotkb:EIF1B(gene name)|psi-mi:EIF1B(display_short)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298160|imex:IM-27563-125	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005866.1|ensembl:ENSG00000114784.4(gene)|ensembl:ENST00000232905.4(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0043024""(ribosomal small subunit binding)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005874(Eukaryotic translation initiation factor SUI1)|interpro:IPR036877|mint:O60739|panther:PTHR10388(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:0nnqCaTD/q0KhGcITR0LD7WLET09606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:1C3E7B69E9F7224D|rigid:KATCZgi7+1Fu1fwjzpkY+WT7Y0E	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60739	uniprotkb:Q5NEM9	intact:EBI-1043343|uniprotkb:Q9UQF8|ensembl:ENSP00000232905.3	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:eif1b_human(display_long)|uniprotkb:Protein translation factor SUI1 homolog GC20(gene name synonym)|uniprotkb:EIF1B(gene name)|psi-mi:EIF1B(display_short)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298150|imex:IM-27563-19	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005866.1|ensembl:ENSG00000114784.4(gene)|ensembl:ENST00000232905.4(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0043024""(ribosomal small subunit binding)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005874(Eukaryotic translation initiation factor SUI1)|interpro:IPR036877|mint:O60739|panther:PTHR10388(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:0nnqCaTD/q0KhGcITR0LD7WLET09606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:BD6AAC16CB5B1773|rigid:yNHOMvp1p/VoougOd2I9IDFJ7kw	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NP50	uniprotkb:Q5NEC5	intact:EBI-741906|uniprotkb:Q9BSZ8|uniprotkb:D3DUV8|ensembl:ENSP00000337477.4|ensembl:ENSP00000393279.2|ensembl:ENSP00000479093.1|ensembl:ENSP00000488570.1	intact:EBI-22297545	psi-mi:shcaf_human(display_long)|uniprotkb:SINHCAF(gene name)|psi-mi:SINHCAF(display_short)|uniprotkb:C12orf14(gene name synonym)|uniprotkb:FAM60A(gene name synonym)|uniprotkb:Protein FAM60A(gene name synonym)|uniprotkb:Tera protein homolog(gene name synonym)|uniprotkb:L4(orf name)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298250|imex:IM-27563-387	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001129283.1|refseq:NP_001129284.1|refseq:NP_067061.1|refseq:XP_016875247.1|refseq:XP_016875248.1|refseq:XP_016875249.1|refseq:XP_016875250.1|refseq:XP_016875251.1|ensembl:ENSG00000139146.14(gene)|ensembl:ENSG00000276371.2(gene)|ensembl:ENST00000337682.9(transcript)|ensembl:ENST00000454658.6(transcript)|ensembl:ENST00000617411.2(transcript)|ensembl:ENST00000633702.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0005634""(nucleus)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0070822""(Sin3-type complex)|go:""GO:1902455""(negative regulation of stem cell population maintenance)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR026065|mint:Q9NP50|refseq:XP_011519105.1|panther:PTHR13422(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:LVESO8KQhobNYQduBQ/iAmNaNTM9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:98718B0EBD771446|rigid:xMDQEr8zgwBvFWrZ5L6JQ6vyDcE	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NV70	uniprotkb:Q5NGE3	intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514.7|ensembl:ENSP00000370695.2	intact:EBI-22297821|uniprotkb:A0A0G2RPC6	psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name)	psi-mi:q5nge3_fratt(display_long)|uniprotkb:FTT_0902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298210|imex:IM-27563-473	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|refseq:XP_005265807.1|refseq:XP_016863898.1|dip:DIP-37579N|ensembl:ENSG00000090989.18(gene)|ensembl:ENST00000346134.11(transcript)|ensembl:ENST00000381295.7(transcript)|go:""GO:0000145""(exocyst)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051607""(defense response to virus)|go:""GO:0090148""(membrane fission)|go:""GO:0090522""(vesicle tethering involved in exocytosis)|go:""GO:0090543""(Flemming body)|interpro:IPR019160|interpro:IPR028258|interpro:IPR048628|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|panther:PTHR16092(orthology-group)"	refseq:YP_169899.1|mint:Q5NGE3	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/28	rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606	rogid:NCB/Hok6C9lpbhvu2mMcLmSbgZs177416	intact-crc:4CF3BC001338DF70|rigid:mMU08QcKxQ9/mGYL747QZMa1Ko8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96DN0	uniprotkb:Q5NES6	intact:EBI-953772|ensembl:ENSP00000266397.2	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:erp27_human(display_long)|uniprotkb:ERP27(gene name)|psi-mi:ERP27(display_short)|uniprotkb:C12orf46(gene name synonym)|uniprotkb:Inactive protein disulfide-isomerase 27(gene name synonym)|uniprotkb:UNQ781/PRO1575(orf name)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298190|imex:IM-27563-21	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_689534.1|refseq:NP_001287713.1|ensembl:ENSG00000139055.7(gene)|ensembl:ENST00000266397.7(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0034976""(response to endoplasmic reticulum stress)|interpro:IPR036249|mint:Q96DN0|rcsb pdb:2L4C|rcsb pdb:4F9Z|panther:PTHR18929(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:QlmYUMPM82wLI35xU26gUAHomTk9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:63291B3CB5FC6274|rigid:cJ8xGdH7L6oYS+F9h9XhsLE/Iws	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P18146	uniprotkb:Q5NFP9	intact:EBI-2834611|ensembl:ENSP00000239938.4	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:egr1_human(display_long)|uniprotkb:EGR1(gene name)|psi-mi:EGR1(display_short)|uniprotkb:KROX24(gene name synonym)|uniprotkb:ZNF225(gene name synonym)|uniprotkb:AT225(gene name synonym)|uniprotkb:Nerve growth factor-induced protein A(gene name synonym)|uniprotkb:Transcription factor ETR103(gene name synonym)|uniprotkb:Transcription factor Zif268(gene name synonym)|uniprotkb:Zinc finger protein 225(gene name synonym)|uniprotkb:Zinc finger protein Krox-24(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298140|imex:IM-27563-123	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000120738.8(gene)|ensembl:ENST00000239938.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009749""(response to glucose)|go:""GO:0010385""(double-stranded methylated DNA binding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032868""(response to insulin)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0033233""(regulation of protein sumoylation)|go:""GO:0035035""(histone acetyltransferase binding)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043523""(regulation of neuron apoptotic process)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0044029""(positive regulation of gene expression via chromosomal CpG island demethylation)|go:""GO:0044729""(hemi-methylated DNA-binding)|go:""GO:0044849""(estrous cycle)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046886""(positive regulation of hormone biosynthetic process)|go:""GO:0060086""(circadian temperature homeostasis)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071504""(cellular response to heparin)|go:""GO:0071506""(cellular response to mycophenolic acid)|go:""GO:0072110""(glomerular mesangial cell proliferation)|go:""GO:0072303""(positive regulation of glomerular metanephric mesangial cell proliferation)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0098759""(cellular response to interleukin-8)|go:""GO:1901875""(positive regulation of post-translational protein modification)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000182""(regulation of progesterone biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR021839|interpro:IPR021849|interpro:IPR036236|mint:P18146|rcsb pdb:4R2A|rcsb pdb:4R2C|rcsb pdb:4R2D|rcsb pdb:4X9J|rcsb pdb:5N14|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-909733|refseq:NP_001955.1|panther:PTHR23235(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:7JnUP8JJaEG/d72DbadDN/gibQ89606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:CAFAB43C66532D30|rigid:HP0q9tn0fe5HsKOll6v7JNUcHEA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NV70	uniprotkb:Q5NHH2	intact:EBI-1045313|uniprotkb:Q504V4|uniprotkb:Q8WUE7|uniprotkb:Q96T15|uniprotkb:Q9NZE4|ensembl:ENSP00000326514.7|ensembl:ENSP00000370695.2	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:exoc1_human(display_long)|uniprotkb:Exocyst complex component Sec3(gene name synonym)|uniprotkb:EXOC1(gene name)|psi-mi:EXOC1(display_short)|uniprotkb:SEC3(gene name synonym)|uniprotkb:SEC3L1(gene name synonym)|uniprotkb:BM-012(orf name)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298200|imex:IM-27563-127	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020095.1|refseq:NP_060731.2|refseq:NP_839955.1|refseq:XP_005265807.1|refseq:XP_016863898.1|dip:DIP-37579N|ensembl:ENSG00000090989.18(gene)|ensembl:ENST00000346134.11(transcript)|ensembl:ENST00000381295.7(transcript)|go:""GO:0000145""(exocyst)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051607""(defense response to virus)|go:""GO:0090148""(membrane fission)|go:""GO:0090522""(vesicle tethering involved in exocytosis)|go:""GO:0090543""(Flemming body)|interpro:IPR019160|interpro:IPR028258|interpro:IPR048628|mint:Q9NV70|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|panther:PTHR16092(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/28	rogid:DKEfnn4CJkBSIdGRfVy+znSPOrc9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:8FF2A8E24EDC4E2A|rigid:8tBE5VEsZ8yl/66CiUo4XFRq/J8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5W0V3	uniprotkb:Q5NH45	intact:EBI-7054959|uniprotkb:Q8IY76|uniprotkb:Q5H9P7|uniprotkb:Q9HCH2|uniprotkb:Q5W0V2|intact:MINT-8201763|ensembl:ENSP00000358251.4	intact:EBI-2796893|uniprotkb:A0A0G2RNJ2	psi-mi:fhi2a_human(display_long)|uniprotkb:FHIP2A(gene name)|psi-mi:FHIP2A(display_short)|uniprotkb:FAM160B1(gene name synonym)|uniprotkb:KIAA1600(gene name synonym)	psi-mi:q5nh45_fratt(display_long)|uniprotkb:lon(gene name)|psi-mi:lon(display_short)|uniprotkb:ATP-dependent protease La(gene name synonym)|uniprotkb:FTT_0626(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298240|imex:IM-27563-129	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001128523.1|refseq:NP_065991.3|ensembl:ENSG00000151553.16(gene)|ensembl:ENST00000369248.9(transcript)|interpro:IPR019384|interpro:IPR045668|interpro:IPR045669|mint:Q5W0V3|panther:PTHR21705(orthology-group)	"go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034605""(cellular response to heat)|go:""GO:0043565""(sequence-specific DNA binding)|interpro:IPR054594|refseq:YP_169647.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR027065|interpro:IPR027417|interpro:IPR027543|refseq:WP_003023412.1|mint:Q5NH45|interpro:IPR046336"	-	comment:mint	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/27	rogid:ztLSJ/Jf2V5nrPCwlBZfAzmrmzM9606	rogid:VbLPJiXznE9s4Ww3dtsvWlgjMfM177416	intact-crc:8EF5AE600B951B72|rigid:bFdcCjPe00I0mgzMx1lAfG7rup0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H6L5	uniprotkb:Q5NIP8	intact:EBI-5664372|uniprotkb:Q9H6K6|uniprotkb:Q9H764|uniprotkb:Q69YN8|uniprotkb:Q9NXM8|ensembl:ENSP00000304642.9	intact:EBI-2796698	psi-mi:retr1_human(display_long)|uniprotkb:RETREG1(gene name)|psi-mi:RETREG1(display_short)|uniprotkb:FAM134B(gene name synonym)|uniprotkb:JK1(gene name synonym)|uniprotkb:Reticulophagy receptor 1(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298230|imex:IM-27563-561	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-61577N|efo:""Orphanet:970""|ensembl:ENSG00000154153.15(gene)|ensembl:ENST00000306320.10(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005730""(nucleolus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0016604""(nuclear body)|go:""GO:0019233""(sensory perception of pain)|go:""GO:0030574""(collagen catabolic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0050872""(white fat cell differentiation)|go:""GO:0061709""(reticulophagy)|go:""GO:0140506""(endoplasmic reticulum-autophagosome adaptor activity)|interpro:IPR043384|interpro:IPR055255|mint:Q9H6L5|rcsb pdb:7BRQ|rcsb pdb:7FB5|refseq:NP_001030022.1|refseq:NP_061873.2|panther:PTHR28659(orthology-group)"	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/26	rogid:9IT3rARBCtNfCAkRklfhF3Q5bf09606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:3D434F8DFB84764F|rigid:1762HuDjndkBdlGNecg7rjRABrs	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13011	uniprotkb:Q5NHH2	intact:EBI-711968|uniprotkb:Q8WVX0|uniprotkb:Q96EZ9|ensembl:ENSP00000221418.3|ensembl:ENSP00000489530.1|uniprotkb:A8K745	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:ech1_human(display_long)|uniprotkb:ECH1(gene name)|psi-mi:ECH1(display_short)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298120|imex:IM-27563-221	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000104823.9(gene)|ensembl:ENSG00000282853.2(gene)|ensembl:ENST00000221418.9(transcript)|ensembl:ENST00000634245.2(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0016020""(membrane)|go:""GO:0051750""(""delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity"")|go:""GO:0070062""(extracellular exosome)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|interpro:IPR045002|mint:Q13011|rcsb pdb:2VRE|rcsb pdb:8SK6|reactome:R-HSA-9033241|reactome:R-HSA-9837999|refseq:NP_001389.2|panther:PTHR43149(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:gh0bwdUu9tkSTHWuySCaTXIQGzI9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:CDE6949B8D11C850|rigid:ODGbRapAN9troKWnU2divzuWpTM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P21802	uniprotkb:Q5NGJ5	intact:EBI-1028658|uniprotkb:P18443|uniprotkb:Q01742|uniprotkb:Q12922|uniprotkb:Q14300|uniprotkb:Q14301|uniprotkb:Q14302|uniprotkb:Q14303|uniprotkb:Q14304|uniprotkb:Q14305|uniprotkb:Q14672|uniprotkb:Q14718|uniprotkb:Q14719|uniprotkb:Q86YI4|uniprotkb:Q96KL9|uniprotkb:Q96KM0|uniprotkb:Q96KM1|uniprotkb:Q96KM2|uniprotkb:Q9NZU2|uniprotkb:Q9NZU3|uniprotkb:Q9UD01|uniprotkb:Q9UD02|uniprotkb:Q9UIH3|uniprotkb:Q9UIH4|uniprotkb:Q9UIH5|uniprotkb:Q9UIH6|uniprotkb:Q9UIH7|uniprotkb:Q9UIH8|uniprotkb:Q9UM87|uniprotkb:Q9UMC6|uniprotkb:Q9UNS7|uniprotkb:Q9UQH7|uniprotkb:Q9UQH8|uniprotkb:Q9UQH9|uniprotkb:Q9UQI0|uniprotkb:Q1KHY5|uniprotkb:B4DFC2|uniprotkb:E7EVR6|uniprotkb:E9PCR0|uniprotkb:Q8IXC7|ensembl:ENSP00000351276.6	intact:EBI-22297738|uniprotkb:A0A0G2RPF6	psi-mi:fgfr2_human(display_long)|uniprotkb:FGFR2(gene name)|psi-mi:FGFR2(display_short)|uniprotkb:BEK(gene name synonym)|uniprotkb:KSAM(gene name synonym)|uniprotkb:Keratinocyte growth factor receptor(gene name synonym)|uniprotkb:KGFR(gene name synonym)|uniprotkb:K-sam(gene name synonym)	psi-mi:q5ngj5_fratt(display_long)|uniprotkb:FTT_0842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298270|imex:IM-27563-629	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-3788N|efo:""Orphanet:1540""|efo:""Orphanet:1555""|efo:""Orphanet:168624""|efo:""Orphanet:207""|efo:""Orphanet:2363""|efo:""Orphanet:313855""|efo:""Orphanet:596008""|efo:""Orphanet:794""|efo:""Orphanet:87""|efo:""Orphanet:93258""|efo:""Orphanet:93259""|efo:""Orphanet:93260""|ensembl:ENSG00000066468.24(gene)|ensembl:ENST00000358487.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001525""(angiogenesis)|go:""GO:0001657""(ureteric bud development)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0002053""(positive regulation of mesenchymal cell proliferation)|go:""GO:0003148""(outflow tract septum morphogenesis)|go:""GO:0003149""(membranous septum morphogenesis)|go:""GO:0003416""(endochondral bone growth)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006915""(apoptotic process)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007409""(axonogenesis)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008288""(boss receptor activity)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0008589""(regulation of smoothened signaling pathway)|go:""GO:0009791""(post-embryonic development)|go:""GO:0009880""(embryonic pattern specification)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009986""(cell surface)|go:""GO:0010518""(positive regulation of phospholipase activity)|go:""GO:0010839""(negative regulation of keratinocyte proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0017134""(fibroblast growth factor binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0021769""(orbitofrontal cortex development)|go:""GO:0021847""(ventricular zone neuroblast division)|go:""GO:0021860""(pyramidal neuron development)|go:""GO:0022612""(gland morphogenesis)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030282""(bone mineralization)|go:""GO:0030324""(lung development)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0030901""(midbrain development)|go:""GO:0030916""(otic vesicle formation)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032808""(lacrimal gland development)|go:""GO:0033688""(regulation of osteoblast proliferation)|go:""GO:0035265""(organ growth)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035602""(fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell)|go:""GO:0035603""(fibroblast growth factor receptor signaling pathway involved in hemopoiesis)|go:""GO:0035604""(fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow)|go:""GO:0035607""(fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0042472""(inner ear morphogenesis)|go:""GO:0042476""(odontogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043235""(receptor complex)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0045165""(cell fate commitment)|go:""GO:0045471""(response to ethanol)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048286""(lung alveolus development)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048557""(embryonic digestive tract morphogenesis)|go:""GO:0048562""(embryonic organ morphogenesis)|go:""GO:0048565""(digestive tract development)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048608""(reproductive structure development)|go:""GO:0048701""(embryonic cranial skeleton morphogenesis)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048730""(epidermis morphogenesis)|go:""GO:0048755""(branching morphogenesis of a nerve)|go:""GO:0048762""(mesenchymal cell differentiation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0051150""(regulation of smooth muscle cell differentiation)|go:""GO:0051781""(positive regulation of cell division)|go:""GO:0055010""(ventricular cardiac muscle tissue morphogenesis)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060076""(excitatory synapse)|go:""GO:0060174""(limb bud formation)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060348""(bone development)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0060442""(branching involved in prostate gland morphogenesis)|go:""GO:0060445""(branching involved in salivary gland morphogenesis)|go:""GO:0060449""(bud elongation involved in lung branching)|go:""GO:0060463""(lung lobe morphogenesis)|go:""GO:0060484""(lung-associated mesenchyme development)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060512""(prostate gland morphogenesis)|go:""GO:0060523""(prostate epithelial cord elongation)|go:""GO:0060527""(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:""GO:0060529""(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:""GO:0060595""(fibroblast growth factor receptor signaling pathway involved in mammary gland specification)|go:""GO:0060601""(lateral sprouting from an epithelium)|go:""GO:0060615""(mammary gland bud formation)|go:""GO:0060664""(epithelial cell proliferation involved in salivary gland morphogenesis)|go:""GO:0060667""(branch elongation involved in salivary gland morphogenesis)|go:""GO:0060670""(branching involved in labyrinthine layer morphogenesis)|go:""GO:0060688""(regulation of morphogenesis of a branching structure)|go:""GO:0060915""(mesenchymal cell differentiation involved in lung development)|go:""GO:0060916""(mesenchymal cell proliferation involved in lung development)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016248(Fibroblast growth factor receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|interpro:IPR050122|mint:P21802|rcsb pdb:1DJS|rcsb pdb:1E0O|rcsb pdb:1EV2|rcsb pdb:1GJO|rcsb pdb:1II4|rcsb pdb:1IIL|rcsb pdb:1NUN|rcsb pdb:1OEC|rcsb pdb:1WVZ|rcsb pdb:2FDB|rcsb pdb:2PSQ|rcsb pdb:2PVF|rcsb pdb:2PVY|rcsb pdb:2PWL|rcsb pdb:2PY3|rcsb pdb:2PZ5|rcsb pdb:2PZP|rcsb pdb:2PZR|rcsb pdb:2Q0B|rcsb pdb:3B2T|rcsb pdb:3CAF|rcsb pdb:3CLY|rcsb pdb:3CU1|rcsb pdb:3DAR|rcsb pdb:3EUU|rcsb pdb:3OJ2|rcsb pdb:3OJM|rcsb pdb:3RI1|rcsb pdb:4J23|rcsb pdb:4J95|rcsb pdb:4J96|rcsb pdb:4J97|rcsb pdb:4J98|rcsb pdb:4J99|rcsb pdb:4WV1|rcsb pdb:5EG3|rcsb pdb:5UGL|rcsb pdb:5UGX|rcsb pdb:5UHN|rcsb pdb:5UI0|rcsb pdb:6AGX|rcsb pdb:6LVK|rcsb pdb:6LVL|rcsb pdb:6V6Q|rcsb pdb:7KIA|rcsb pdb:7KIE|rcsb pdb:7OZY|rcsb pdb:8E1X|rcsb pdb:8H75|rcsb pdb:8STG|rcsb pdb:8SWE|rcsb pdb:8U1F|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-190375|reactome:R-HSA-190377|reactome:R-HSA-2023837|reactome:R-HSA-2033519|reactome:R-HSA-2219530|reactome:R-HSA-5654221|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654727|reactome:R-HSA-5655253|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851708|reactome:R-HSA-8853333|refseq:NP_000132.3|refseq:NP_001138385.1|refseq:NP_001138386.1|refseq:NP_001138387.1|refseq:NP_001138388.1|refseq:NP_001138389.1|refseq:NP_001138390.1|refseq:NP_001138391.1|refseq:NP_001307583.1|refseq:NP_001307587.1|refseq:NP_075259.4|refseq:NP_075418.1|panther:PTHR24416(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|interpro:IPR050330|refseq:WP_003020808.1|refseq:YP_169847.1|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|mint:Q5NGJ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:XW6x8AHgdb29IL3MhUFWpv4jaqE9606	rogid:/Dq7r5H2A4RbaDlrrHYQHMOGtbc177416	intact-crc:D15598FFAE14C4D3|rigid:AlYX4WQ60mjJzqWDIg9NSOEHLxg	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00367	uniprotkb:Q5NEC5	intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865.4|uniprotkb:B3KV55|uniprotkb:B4DGN5	intact:EBI-22297545	psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298337|imex:IM-27563-481	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:35878""|ensembl:ENSG00000148672.10(gene)|ensembl:ENST00000277865.5(transcript)|go:""GO:0004352""(""glutamate dehydrogenase (NAD+) activity"")|go:""GO:0004353""(""glutamate dehydrogenase [NAD(P)+] activity"")|go:""GO:0004354""(""glutamate dehydrogenase (NADP+) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006538""(glutamate catabolic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0021762""(substantia nigra development)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043531""(ADP binding)|go:""GO:0070403""(NAD+ binding)|go:""GO:0070728""(L-leucine binding)|go:""GO:0072350""(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|interpro:IPR046346|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|rcsb pdb:7UZM|rcsb pdb:8KGY|rcsb pdb:8SK8|rcsb pdb:8W4J|reactome:R-HSA-2151201|reactome:R-HSA-8964539|reactome:R-HSA-9837999|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|refseq:NP_005262.1|panther:PTHR11606(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:D7BDC8187A9B525A|rigid:VrPfAw8C4uPULdaMlI/3g2oqzVw	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P02671	uniprotkb:Q5NEC5	intact:EBI-348571|uniprotkb:Q9BX62|uniprotkb:Q9UCH2|uniprotkb:A8K3E4|ensembl:ENSP00000498441.1|uniprotkb:Q4QQH7|uniprotkb:D3DP14|uniprotkb:D3DP15	intact:EBI-22297545	psi-mi:fiba_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298260|imex:IM-27563-293	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"reactome:R-HSA-216083|ensembl:ENSG00000171560.18(gene)|ensembl:ENST00000651975.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031639""(plasminogen activation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043152""(induction of bacterial agglutination)|go:""GO:0045087""(innate immune response)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0046872""(metal ion binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051258""(protein polymerization)|go:""GO:0051592""(response to calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0072377""(blood coagulation, common pathway)|go:""GO:0072378""(blood coagulation, fibrin clot formation)|go:""GO:0072562""(blood microparticle)|go:""GO:0090277""(positive regulation of peptide hormone secretion)|reactome:R-HSA-354192|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903561""(extracellular vesicle)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR021996|interpro:IPR036056|interpro:IPR037579|mint:P02671|rcsb pdb:1BBR|rcsb pdb:1DM4|rcsb pdb:1FPH|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZD|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:1YCP|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3AT0|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4F27|rcsb pdb:5CFA|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-977225|refseq:NP_000499.1|refseq:NP_068657.1|dip:DIP-29643N|efo:""Orphanet:101041""|efo:""Orphanet:248408""|efo:""Orphanet:93562""|efo:""Orphanet:98880""|efo:""Orphanet:98881""|panther:PTHR47221(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/22	rogid:khlQGVpd+6qZLTrsT9KxlxgjMR09606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:4E16F58C1D30E01C|rigid:n00tMSjtb1F6sRz0rQbrXaYdIlk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HC38	uniprotkb:Q5NFC5	intact:EBI-1049764|uniprotkb:Q96B89|uniprotkb:Q9H3J8|uniprotkb:Q9HC37|uniprotkb:Q9NVN1|uniprotkb:D3DTG9|uniprotkb:D3DTH1|ensembl:ENSP00000301328.5	intact:EBI-22298320|uniprotkb:A0A0G2RPT0	psi-mi:glod4_human(display_long)|uniprotkb:GLOD4(gene name)|psi-mi:GLOD4(display_short)|uniprotkb:C17orf25(gene name synonym)|uniprotkb:CGI-150(orf name)|uniprotkb:My027(orf name)	psi-mi:q5nfc5_fratt(display_long)|uniprotkb:General secretion pathway protein H(gene name synonym)|uniprotkb:FTT_1314c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298327|imex:IM-27563-631	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057164.3|ensembl:ENSG00000167699.14(gene)|ensembl:ENST00000301328.9(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR029068|interpro:IPR037523|interpro:IPR043193|interpro:IPR043194|mint:Q9HC38|rcsb pdb:3ZI1|panther:PTHR46466(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0015627""(type II protein secretion system complex)|go:""GO:0015628""(protein secretion by the type II secretion system)|interpro:IPR045584|refseq:WP_003022044.1|refseq:YP_170267.1|mint:Q5NFC5|interpro:IPR022346"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:0Xu9EPSkmX9t8j0yLaCyBLhKcUs9606	rogid:0X6MsYyGE7Tjd9I6bLIdEfgErGo177416	intact-crc:DBF0FDEB2D86F977|rigid:R17SQryFnU+dmlcYCcwGwRlMKfI	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z7B0	uniprotkb:Q5NHH2	intact:EBI-16370558|uniprotkb:B2RMU6|uniprotkb:Q5VUL6|uniprotkb:Q86TC3|uniprotkb:Q8N8B9|uniprotkb:Q96SK6|uniprotkb:Q9NVI8|uniprotkb:Q9ULE5|ensembl:ENSP00000237172.7	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:flip1_human(display_long)|uniprotkb:FILIP1(gene name)|psi-mi:FILIP1(display_short)|uniprotkb:KIAA1275(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298280|imex:IM-27563-225	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001276916.1|refseq:NP_001287795.1|refseq:NP_056502.1|refseq:XP_005248770.1|refseq:XP_011534058.1|panther:PTHR23166(orthology-group)|ensembl:ENSG00000118407.15(gene)|ensembl:ENST00000237172.12(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099010""(modification of postsynaptic structure)|go:""GO:1903119""(protein localization to actin cytoskeleton)|interpro:IPR019131|interpro:IPR050719|mint:Q7Z7B0|reactome:R-HSA-9013405"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:Wt+by68gyWdQ50nKiSNP8Njonq09606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:A9E138E8FB3C9ACB|rigid:5QAzE/zgoFLqEmHRKsEB9+5iK3U	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99518	uniprotkb:Q5NFP9	intact:EBI-2825201|uniprotkb:Q5EBX4|uniprotkb:Q86U73|uniprotkb:Q9BRX1|ensembl:ENSP00000209929.8	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:fmo2_human(display_long)|uniprotkb:FMO2(gene name)|psi-mi:FMO2(display_short)|uniprotkb:Dimethylaniline oxidase 2(gene name synonym)|uniprotkb:FMO 1B1(gene name synonym)|uniprotkb:Pulmonary flavin-containing monooxygenase 2(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298290|imex:IM-27563-227	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001451.2|ensembl:ENSG00000094963.14(gene)|ensembl:ENST00000209929.10(transcript)|go:""GO:0004499""(N,N-dimethylaniline monooxygenase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006082""(organic acid metabolic process)|go:""GO:0006739""(NADP metabolic process)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0009404""(toxin metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0046322""(negative regulation of fatty acid oxidation)|go:""GO:0047822""(hypotaurine monooxygenase activity)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0050661""(NADP binding)|go:""GO:0070995""(obsolete NADPH oxidation)|go:""GO:0072592""(oxygen metabolic process)|go:""GO:0097009""(energy homeostasis)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR002254(""Flavin-containing monooxygenase (FMO) 2"")|interpro:IPR020946|interpro:IPR036188|interpro:IPR050346|mint:Q99518|reactome:R-HSA-217271|panther:PTHR23023(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:xZ4QTuaUuifDiz9ShwAtObhvPqU9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:6C84D8119C6B20F8|rigid:PHDYC4h+u5X10cNZEJOH8251Ld0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WU20	uniprotkb:Q5NEC5	intact:EBI-1104330|uniprotkb:O43558|uniprotkb:Q7LDQ6|uniprotkb:B0LPF2|uniprotkb:B2R684|ensembl:ENSP00000381083.2|ensembl:ENSP00000447241.1|ensembl:ENSP00000450048.1	intact:EBI-22297545	psi-mi:frs2_human(display_long)|uniprotkb:FRS2(gene name)|psi-mi:FRS2(display_short)|uniprotkb:Suc1-associated neurotrophic factor target 1(gene name synonym)|uniprotkb:FGFR-signaling adaptor SNT(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298300|imex:IM-27563-389	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001036020.1|refseq:NP_006645.3|refseq:NP_001265280.1|refseq:NP_001265282.1|refseq:NP_001265283.1|refseq:NP_001265284.1|refseq:NP_001265285.1|refseq:NP_001265286.1|ensembl:ENSG00000166225.9(gene)|ensembl:ENST00000397997.6(transcript)|ensembl:ENST00000549921.6(transcript)|ensembl:ENST00000550389.5(transcript)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001759""(organ induction)|go:""GO:0003281""(ventricular septum development)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005104""(fibroblast growth factor receptor binding)|go:""GO:0005168""(neurotrophin TRKA receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0007185""(cell surface receptor protein tyrosine phosphatase signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0008595""(anterior/posterior axis specification, embryo)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0019211""(phosphatase activator activity)|go:""GO:0030900""(forebrain development)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0046619""(lens placode formation involved in camera-type eye formation)|go:""GO:0050678""(regulation of epithelial cell proliferation)|go:""GO:0060527""(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:""GO:0070307""(lens fiber cell development)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:2000726""(negative regulation of cardiac muscle cell differentiation)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR038742|interpro:IPR050996|mint:Q8WU20|rcsb pdb:1XR0|rcsb pdb:2MFQ|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-170968|reactome:R-HSA-201556|reactome:R-HSA-2219530|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-9028731|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9725370|refseq:XP_016874206.1|refseq:XP_016874207.1|refseq:XP_016874208.1|panther:PTHR21258(orthology-group)|ensembl:ENSP00000381083.2|ensembl:ENSP00000450048.1|ensembl:ENSP00000447241.1"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:7tSNEY7uVWJZtQ3l1zd1xhkaoUU9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:48F9EFC338D742A4|rigid:iYv9qPhr75UGn3PGAoM5ZeEVuqg	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q969S9	uniprotkb:Q5NES6	intact:EBI-2371750|uniprotkb:Q8WYI0|uniprotkb:A0AR28|uniprotkb:Q8N6D8|uniprotkb:Q9H6Z1|ensembl:ENSP00000296805.3|ensembl:ENSP00000427004.1|intact:EBI-28986334	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:rrf2m_human(display_long)|uniprotkb:GFM2(gene name)|psi-mi:GFM2(display_short)|uniprotkb:EFG2(gene name synonym)|uniprotkb:Elongation factor G 2, mitochondrial(gene name synonym)|uniprotkb:Elongation factor G2(gene name synonym)|uniprotkb:MSTP027(orf name)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298310|imex:IM-27563-295	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164347.18(gene)|ensembl:ENST00000296805.8(transcript)|ensembl:ENST00000509430.5(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0032543""(mitochondrial translation)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0070126""(mitochondrial translational termination)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR030851|interpro:IPR031157|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|interpro:IPR053905|mint:Q969S9|rcsb pdb:7L20|rcsb pdb:7NSH|reactome:R-HSA-5419276|refseq:NP_001268231.1|refseq:NP_115756.2|refseq:NP_733781.1|refseq:NP_733792.1|refseq:XP_016865475.1|dip:DIP-53437N|efo:""Orphanet:565624""|panther:PTHR43261(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/25	rogid:tDdVCBcztI95aArJCyypUgUrWOw9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:7CCB69E4D72F4DDE|rigid:1ENwYXcGGk5WqtZGST+0rTBScLc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5T7V8	uniprotkb:Q5NHH2	intact:EBI-3917143|uniprotkb:Q6P1P9|uniprotkb:Q9HAE6|uniprotkb:Q9Y350|uniprotkb:Q49A22|ensembl:ENSP00000356737.4	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:gorab_human(display_long)|uniprotkb:GORAB(gene name)|psi-mi:GORAB(display_short)|uniprotkb:NTKLBP1(gene name synonym)|uniprotkb:SCYL1BP1(gene name synonym)|uniprotkb:N-terminal kinase-like-binding protein 1(gene name synonym)|uniprotkb:SCY1-like 1-binding protein 1(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298347|imex:IM-27563-303	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000120370.14(gene)|ensembl:ENST00000367763.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0045880""(positive regulation of smoothened signaling pathway)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR007033(Protein of unknown function DUF662)|mint:Q5T7V8|refseq:NP_001139511.1|refseq:NP_001307181.1|refseq:NP_689494.2|efo:""Orphanet:2078""|panther:PTHR21470(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:o3G28P0aQZuEmyJGwL4GSYXUEkY9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:BC2BB41F543875F9|rigid:AgKTOldQiyE9CEO9kTHBk5wMAdY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0VDF9	uniprotkb:Q5NHT8	intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623.3	intact:EBI-2806309	psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym)|uniprotkb:Heat shock protein family A member 14(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298387|imex:IM-27563-133	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057383.2|ensembl:ENSG00000187522.16(gene)|ensembl:ENST00000378372.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N|panther:PTHR19375(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/05	rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:DF4375A4D4CB0254|rigid:24s+vfvVRzlnnbVog6/WXk7/pRo	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKV0	uniprotkb:Q5NES6	intact:EBI-765444|uniprotkb:O94845|uniprotkb:O95028|uniprotkb:Q2M2R6|uniprotkb:Q86SL1|uniprotkb:Q86US3|uniprotkb:A7E2F3|ensembl:ENSP00000410337.2|uniprotkb:B7Z917|uniprotkb:B7Z4I4|uniprotkb:B7Z928|uniprotkb:B7Z940|uniprotkb:C9JS87|uniprotkb:E7EX34|uniprotkb:F8W9E0|intact:EBI-28970749	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:hdac9_human(display_long)|uniprotkb:Histone deacetylase 7B(gene name synonym)|uniprotkb:Histone deacetylase-related protein(gene name synonym)|uniprotkb:MEF2-interacting transcription repressor MITR(gene name synonym)|uniprotkb:HDAC9(gene name)|psi-mi:HDAC9(display_short)|uniprotkb:HDAC7(gene name synonym)|uniprotkb:HDAC7B(gene name synonym)|uniprotkb:KIAA0744(gene name synonym)|uniprotkb:HDRP(gene name synonym)|uniprotkb:MITR(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298367|imex:IM-27563-131	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001308818.1|refseq:NP_848510.1|refseq:NP_848512.1|refseq:NP_001191073.1|refseq:NP_001191074.1|refseq:NP_001191075.1|refseq:NP_001191076.1|refseq:NP_001191077.1|refseq:NP_055522.1|refseq:NP_478056.1|ensembl:ENSG00000048052.25(gene)|ensembl:ENST00000432645.6(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0004407""(histone deacetylase activity)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0006954""(inflammatory response)|go:""GO:0007507""(heart development)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030183""(B cell differentiation)|go:""GO:0031078""(histone H3K14 deacetylase activity, hydrolytic mechanism)|go:""GO:0032129""(histone H3K9 deacetylase activity, hydrolytic mechanism)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0033558""(protein lysine deacetylase activity)|go:""GO:0034739""(histone H4K16 deacetylase activity, hydrolytic mechanism)|go:""GO:0034983""(peptidyl-lysine deacetylation)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042113""(B cell activation)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048742""(regulation of skeletal muscle fiber development)|go:""GO:0051153""(regulation of striated muscle cell differentiation)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140937""(histone H4K12 deacetylase activity, hydrolytic mechanism)|go:""GO:0180032""(histone H4K5 deacetylase activity, hydrolytic mechanism)|go:""GO:0180033""(histone H4K8 deacetylase activity, hydrolytic mechanism)|go:""GO:1990162""(histone H3K4 deacetylase activity, hydrolytic mechanism)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR037138|interpro:IPR046949|mint:Q9UKV0|rcsb pdb:8Q9N|rcsb pdb:8Q9R|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|refseq:NP_001308797.1|refseq:NP_001308798.1|refseq:NP_001308799.1|refseq:NP_001308800.1|refseq:NP_001308801.1|refseq:NP_001308802.1|refseq:NP_001308803.1|refseq:NP_001308804.1|refseq:NP_001308805.1|refseq:NP_001308806.1|refseq:NP_001308807.1|refseq:NP_001308808.1|refseq:NP_001308813.1|refseq:NP_001308814.1|refseq:NP_001308815.1|refseq:NP_001308816.1|refseq:NP_001308817.1|refseq:NP_001308819.1|refseq:NP_001308820.1|refseq:NP_001308822.1|refseq:NP_001308823.1|refseq:NP_001308824.1|refseq:NP_001308825.1|refseq:NP_001308826.1|refseq:NP_001308827.1|refseq:NP_001308828.1|refseq:NP_001308829.1|refseq:NP_001308830.1|refseq:NP_001308831.1|refseq:XP_016868315.1|refseq:XP_016868317.1|refseq:XP_011513940.1|refseq:XP_011513941.1|dip:DIP-39904N|panther:PTHR10625(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:oFAc6CP+RY58lEB4qPxWnM90ecg9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:89EA77C7B60D1692|rigid:ITTHr5S4H4TNbnsxkh0Lm4M8To8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IX15	uniprotkb:Q5NHH2	intact:EBI-10742083|uniprotkb:A1L445|uniprotkb:B4DZ80|uniprotkb:F8WCA3|uniprotkb:Q6P049|uniprotkb:Q86XB6|uniprotkb:Q9P2A5|ensembl:ENSP00000350049.4	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:homez_human(display_long)|uniprotkb:HOMEZ(gene name)|psi-mi:HOMEZ(display_short)|uniprotkb:Homeodomain leucine zipper-containing factor(gene name synonym)|uniprotkb:KIAA1443(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298377|imex:IM-27563-563	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_065885.2|ensembl:ENSG00000290292.10(gene)|ensembl:ENST00000357460.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR024578|mint:Q8IX15|rcsb pdb:2ECC|rcsb pdb:2YS9|panther:PTHR15467(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:t/jhjPnrNTxtpwGbiBblgwul0209606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:FC27DE8F71F79A56|rigid:nc6CVZgEcgvjoOnFdBxxQfgkm/s	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0VDF9	uniprotkb:Q5NHH2	intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623.3	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym)|uniprotkb:Heat shock protein family A member 14(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298397|imex:IM-27563-229	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057383.2|ensembl:ENSG00000187522.16(gene)|ensembl:ENST00000378372.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N|panther:PTHR19375(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/05	rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:F95741457D8F344C|rigid:0jLhvtCzH5AEWW1Ux8ejJuXPEHA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86WP2	uniprotkb:Q5NFP9	intact:EBI-2349758|ensembl:ENSP00000421202.2|uniprotkb:A6NKW3|uniprotkb:Q6NSH6|uniprotkb:Q9H785|uniprotkb:Q9H0D4|uniprotkb:Q9NSN4|intact:EBI-28972285	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:gpbp1_human(display_long)|uniprotkb:GPBP1(gene name)|psi-mi:GPBP1(display_short)|uniprotkb:GPBP(gene name synonym)|uniprotkb:SSH6(gene name synonym)|uniprotkb:GC-rich promoter-binding protein 1(gene name synonym)|uniprotkb:Vascular wall-linked protein(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298357|imex:IM-27563-391	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000062194.16(gene)|ensembl:ENST00000506184.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR028128|mint:Q86WP2|refseq:NP_001120707.2|refseq:NP_001120708.1|refseq:NP_001190175.1|refseq:NP_075064.1|refseq:XP_016865245.1|refseq:XP_016865246.1|refseq:XP_016865247.1|refseq:XP_016865248.1|panther:PTHR14339(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:YpnFRXC1FDOxqNl2Dq67tJRNO6o9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:69FF8FC8899E0594|rigid:G+CIiJLxFijZGe3mHpwD0cBLjUM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48551	uniprotkb:Q5NIP8	intact:EBI-958408|uniprotkb:A8KAJ4|uniprotkb:Q6FHD7|uniprotkb:D3DSE8|uniprotkb:D3DSE9|uniprotkb:Q15467|ensembl:ENSP00000343957.5|ensembl:ENSP00000508013.1	intact:EBI-2796698	psi-mi:inar2_human(display_long)|uniprotkb:IFNAR2(gene name)|psi-mi:IFNAR2(display_short)|uniprotkb:IFNARB(gene name synonym)|uniprotkb:Type I interferon receptor 2(gene name synonym)|uniprotkb:IFNABR(gene name synonym)|uniprotkb:Interferon alpha binding protein(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298514|imex:IM-27563-231	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:431166""|dip:DIP-945N|ensembl:ENSG00000159110.22(gene)|ensembl:ENST00000342136.9(transcript)|ensembl:ENST00000683941.1(transcript)|go:""GO:0004905""(type I interferon receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008269""(JAK pathway signal transduction adaptor activity)|go:""GO:0009615""(response to virus)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0019962""(type I interferon binding)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042018""(interleukin-22 receptor activity)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0098586""(cellular response to virus)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116|interpro:IPR050650|mint:P48551|rcsb pdb:1N6U|rcsb pdb:1N6V|rcsb pdb:2HYM|rcsb pdb:2KZ1|rcsb pdb:2LAG|rcsb pdb:3S8W|rcsb pdb:3S9D|rcsb pdb:3SE3|rcsb pdb:3SE4|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191|reactome:R-HSA-9705671|reactome:R-HSA-9833109|refseq:NP_000865.2|refseq:NP_001276054.1|refseq:NP_001276055.1|refseq:NP_001276057.1|refseq:NP_997467.1|refseq:NP_997468.1|panther:PTHR20859(orthology-group)"	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:n9jPySJ4jlqmT6QgmSlEeNLwUog9606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:9B2B5F56F42AFDAF|rigid:NUju9ItSsBB9SypdMY/bgeBHbqM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NX62	uniprotkb:Q5NES6	intact:EBI-20838470|intact:EBI-28986553|uniprotkb:Q6NVY7|ensembl:ENSP00000262644.4	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	"psi-mi:impa3_human(display_long)|uniprotkb:BPNT2(gene name)|psi-mi:BPNT2(display_short)|uniprotkb:""3'(2'), 5'-bisphosphate nucleotidase 2""(gene name synonym)|uniprotkb:IMPA3(gene name synonym)|uniprotkb:IMPAD1(gene name synonym)|uniprotkb:Inositol monophosphatase domain-containing protein 1(gene name synonym)|uniprotkb:Myo-inositol monophosphatase A3(gene name synonym)|uniprotkb:Phosphoadenosine phosphate 3'-nucleotidase(gene name synonym)"	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298562|imex:IM-27563-27	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR43028(orthology-group)|efo:""Orphanet:280586""|ensembl:ENSG00000104331.9(gene)|ensembl:ENST00000262644.9(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001958""(endochondral ossification)|go:""GO:0002063""(chondrocyte development)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005829""(cytosol)|go:""GO:0008254""(3'-nucleotidase activity)|go:""GO:0008441""(""3'(2'),5'-bisphosphate nucleotidase activity"")|go:""GO:0009791""(post-embryonic development)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0030204""(obsolete chondroitin sulfate metabolic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0097657""(3',5'-nucleotide bisphosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR050725|mint:Q9NX62|reactome:R-HSA-156584|refseq:NP_060283.3"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:ZoiQ47lNFVJI83t+r49P4N5+RV09606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:F741DE6E4F20C5C9|rigid:07zVFdKKg/tupLNypBd4p3sNRe0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0VDF9	uniprotkb:Q5NEM9	intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623.3	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym)|uniprotkb:Heat shock protein family A member 14(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298434|imex:IM-27563-565	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057383.2|ensembl:ENSG00000187522.16(gene)|ensembl:ENST00000378372.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N|panther:PTHR19375(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/05	rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:9096D1215854074E|rigid:9culj/H7ny7u052LdViRI9SKpVc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0VDF9	uniprotkb:Q5NEQ5	intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623.3	intact:EBI-2808269|uniprotkb:A0A0G2RQ71	psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym)|uniprotkb:Heat shock protein family A member 14(gene name synonym)	psi-mi:q5neq5_fratt(display_long)|uniprotkb:Polyphosphate kinase PPK2(gene name synonym)|uniprotkb:FTT_1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298424|imex:IM-27563-135	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057383.2|ensembl:ENSG00000187522.16(gene)|ensembl:ENST00000378372.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N|panther:PTHR19375(orthology-group)"	"interpro:IPR016898(Polyphosphate kinase 2, predicted)|interpro:IPR022488|interpro:IPR022486|refseq:YP_170487.1|refseq:WP_003014894.1|interpro:IPR027417|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0046872""(metal ion binding)|rcsb pdb:4YEG|rcsb pdb:5LL0|rcsb pdb:5LLB|rcsb pdb:5LLF|mint:Q5NEQ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/05	rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606	rogid:3hIShFXVmkZdI9gV6zbu32j30jM177416	intact-crc:6C66BBC465142E2C|rigid:TZXrjaLFTO18Hb6MoixrlTxqsqc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0VDF9	uniprotkb:Q5NFA6	intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623.3	intact:EBI-22298407|uniprotkb:A0A0G2RN16	psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym)|uniprotkb:Heat shock protein family A member 14(gene name synonym)	psi-mi:q5nfa6_fratt(display_long)|uniprotkb:FTT_1334c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298414|imex:IM-27563-393	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057383.2|ensembl:ENSG00000187522.16(gene)|ensembl:ENST00000378372.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N|panther:PTHR19375(orthology-group)"	refseq:WP_003022083.1|refseq:YP_170286.1|mint:Q5NFA6	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/05	rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606	rogid:dwncQFHMLwTw/qNY05nJMJRnw9A177416	intact-crc:6F3617E41C74743A|rigid:dcXxCiRYezapq8/eQbiqmdr/+kY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48551	uniprotkb:Q5NEC5	intact:EBI-958408|uniprotkb:A8KAJ4|uniprotkb:Q6FHD7|uniprotkb:D3DSE8|uniprotkb:D3DSE9|uniprotkb:Q15467|ensembl:ENSP00000343957.5|ensembl:ENSP00000508013.1	intact:EBI-22297545	psi-mi:inar2_human(display_long)|uniprotkb:IFNAR2(gene name)|psi-mi:IFNAR2(display_short)|uniprotkb:IFNARB(gene name synonym)|uniprotkb:Type I interferon receptor 2(gene name synonym)|uniprotkb:IFNABR(gene name synonym)|uniprotkb:Interferon alpha binding protein(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298504|imex:IM-27563-395	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:431166""|dip:DIP-945N|ensembl:ENSG00000159110.22(gene)|ensembl:ENST00000342136.9(transcript)|ensembl:ENST00000683941.1(transcript)|go:""GO:0004905""(type I interferon receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008269""(JAK pathway signal transduction adaptor activity)|go:""GO:0009615""(response to virus)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0019962""(type I interferon binding)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042018""(interleukin-22 receptor activity)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0098586""(cellular response to virus)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116|interpro:IPR050650|mint:P48551|rcsb pdb:1N6U|rcsb pdb:1N6V|rcsb pdb:2HYM|rcsb pdb:2KZ1|rcsb pdb:2LAG|rcsb pdb:3S8W|rcsb pdb:3S9D|rcsb pdb:3SE3|rcsb pdb:3SE4|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191|reactome:R-HSA-9705671|reactome:R-HSA-9833109|refseq:NP_000865.2|refseq:NP_001276054.1|refseq:NP_001276055.1|refseq:NP_001276057.1|refseq:NP_997467.1|refseq:NP_997468.1|panther:PTHR20859(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:n9jPySJ4jlqmT6QgmSlEeNLwUog9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:975C1FE9B8000C60|rigid:Ux9IuSoL+Hc4V8oSV4HDn5ew7C8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P53990	uniprotkb:Q5NGE3	intact:EBI-945994|intact:EBI-4324656|uniprotkb:A8KAH5|uniprotkb:Q9BQ81|uniprotkb:Q9BWN2|uniprotkb:Q3SYM4|uniprotkb:J3QLU7	intact:EBI-22297821|uniprotkb:A0A0G2RPC6	psi-mi:ist1_human(display_long)|uniprotkb:IST1(gene name)|psi-mi:IST1(display_short)|uniprotkb:Putative MAPK-activating protein PM28(gene name synonym)|uniprotkb:KIAA0174(gene name synonym)|uniprotkb:Charged multivesicular body protein 8(gene name synonym)	psi-mi:q5nge3_fratt(display_long)|uniprotkb:FTT_0902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298572|imex:IM-27563-233	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055576.2|refseq:NP_001257904.1|refseq:NP_001257906.1|refseq:NP_001257905.1|refseq:NP_001257907.1|go:""GO:0000785""(chromatin)|go:""GO:0005576""(extracellular region)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0008104""(protein localization)|go:""GO:0015031""(protein transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030496""(midbody)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0048668""(collateral sprouting)|go:""GO:0048672""(positive regulation of collateral sprouting)|go:""GO:0051301""(cell division)|go:""GO:0061640""(cytoskeleton-dependent cytokinesis)|go:""GO:0061952""(midbody abscission)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090541""(MIT domain binding)|go:""GO:0090543""(Flemming body)|go:""GO:1904903""(ESCRT III complex disassembly)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|interpro:IPR042277|rcsb pdb:3FRR|rcsb pdb:3FRS|rcsb pdb:3JC1|rcsb pdb:4U7E|rcsb pdb:4U7I|rcsb pdb:4U7Y|rcsb pdb:4WZX|rcsb pdb:6E8G|rcsb pdb:6TZ4|rcsb pdb:6TZ5|rcsb pdb:6TZA|rcsb pdb:7S7J|rcsb pdb:8UC6|reactome:R-HSA-6798695|reactome:R-HSA-9668328|mint:P53990|dip:DIP-42546N|ensembl:ENST00000329908.12|ensembl:ENSP00000330408.8|ensembl:ENSG00000182149.21|ensembl:ENST00000378798.9|ensembl:ENSP00000368075.5|ensembl:ENST00000378799.11|ensembl:ENSP00000368076.6|ensembl:ENST00000535424.5|ensembl:ENSP00000438399.1|ensembl:ENST00000538850.5|ensembl:ENSP00000463711.1|ensembl:ENST00000541571.6|ensembl:ENSP00000455860.1|ensembl:ENST00000544564.5|ensembl:ENSP00000457844.1|ensembl:ENST00000606369.5|ensembl:ENSP00000475853.1|panther:PTHR12161(orthology-group)"	refseq:YP_169899.1|mint:Q5NGE3	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:RbWwKZ+sftO2x3UkFz8zAxVi2CU9606	rogid:NCB/Hok6C9lpbhvu2mMcLmSbgZs177416	intact-crc:74E5D6FF5BD390C5|rigid:twts8k9CY+9Zn+5+W4nhI0SwpaE	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40189	uniprotkb:Q5NG28	intact:EBI-1030834|uniprotkb:Q9UQ41|uniprotkb:A0N0L4|uniprotkb:Q5FC04|ensembl:ENSP00000370698.2|ensembl:ENSP00000462158.1|ensembl:ENSP00000513858.1	intact:EBI-2802768|uniprotkb:A0A0G2RPI9	psi-mi:il6rb_human(display_long)|uniprotkb:IL6ST(gene name)|psi-mi:IL6ST(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:CDw130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:q5ng28_fratt(display_long)|uniprotkb:dacD(gene name)|psi-mi:dacD(display_short)|uniprotkb:FTT_1029(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298524|imex:IM-27563-635	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:656283""|efo:""Orphanet:656300""|efo:""Orphanet:656313""|dip:DIP-95N|ensembl:ENSG00000134352.21(gene)|ensembl:ENST00000381298.7(transcript)|ensembl:ENST00000502326.7(transcript)|ensembl:ENST00000698645.1(transcript)|go:""GO:0002675""(positive regulation of acute inflammatory response)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0004897""(ciliary neurotrophic factor receptor activity)|go:""GO:0004921""(interleukin-11 receptor activity)|go:""GO:0005127""(ciliary neurotrophic factor receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0005896""(interleukin-6 receptor complex)|go:""GO:0005900""(oncostatin-M receptor complex)|go:""GO:0005977""(glycogen metabolic process)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010613""(positive regulation of cardiac muscle hypertrophy)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019838""(growth factor binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0019970""(interleukin-11 binding)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030425""(dendrite)|go:""GO:0034097""(response to cytokine)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038165""(oncostatin-M-mediated signaling pathway)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045121""(membrane raft)|go:""GO:0045509""(interleukin-27 receptor activity)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0048711""(positive regulation of astrocyte differentiation)|go:""GO:0048861""(leukemia inhibitory factor signaling pathway)|go:""GO:0060576""(intestinal epithelial cell development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0070104""(negative regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070106""(interleukin-27-mediated signaling pathway)|go:""GO:0070110""(ciliary neurotrophic factor receptor complex)|go:""GO:0070120""(ciliary neurotrophic factor-mediated signaling pathway)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097696""(cell surface receptor signaling pathway via STAT)|go:""GO:1901731""(positive regulation of platelet aggregation)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|interpro:IPR050379|mint:P40189|rcsb pdb:1BJ8|rcsb pdb:1BQU|rcsb pdb:1I1R|rcsb pdb:1P9M|rcsb pdb:1PVH|rcsb pdb:3L5H|rcsb pdb:3L5I|rcsb pdb:3L5J|rcsb pdb:7U7N|rcsb pdb:8D6A|rcsb pdb:8D74|rcsb pdb:8D7R|rcsb pdb:8D82|rcsb pdb:8D85|rcsb pdb:8DPS|rcsb pdb:8DPT|rcsb pdb:8DPU|rcsb pdb:8UPA|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-6788467|reactome:R-HSA-8984722|reactome:R-HSA-9020956|refseq:NP_001177910.1|refseq:NP_002175.2|refseq:NP_786943.1|panther:PTHR23036(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015956(Penicillin-binding protein-associated)|interpro:IPR018044|interpro:IPR012907(Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal)|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:YP_170014.1|refseq:WP_003021136.1|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|rcsb pdb:6OSU|mint:Q5NG28|interpro:IPR037167"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:0DhlsbEh3ZiKomQFf+5mjd6hUOM9606	rogid:EYTPcD8JUkej9Gvps0ogQD5aQ1c177416	intact-crc:B797795EBDADFA12|rigid:SPAiajyWV57wlC+OLN9qauFukdc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11021	uniprotkb:Q5NES6	intact:EBI-354921|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61|ensembl:ENSP00000324173.6	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298444|imex:IM-27563-483	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005338.1|ensembl:ENSG00000044574.9(gene)|ensembl:ENST00000324460.7(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006983""(ER overload response)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021589""(cerebellum structural organization)|go:""GO:0021680""(cerebellar Purkinje cell layer development)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030291""(protein serine/threonine kinase inhibitor activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031204""(post-translational protein targeting to membrane, translocation)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035437""(maintenance of protein localization in endoplasmic reticulum)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042026""(protein refolding)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042470""(melanosome)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060904""(regulation of protein folding in endoplasmic reticulum)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071353""(cellular response to interleukin-4)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1903891""(regulation of ATF6-mediated unfolded protein response)|go:""GO:1903894""(regulation of IRE1-mediated unfolded protein response)|go:""GO:1903895""(negative regulation of IRE1-mediated unfolded protein response)|go:""GO:1903897""(regulation of PERK-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|rcsb pdb:7N1R|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-8874177|reactome:R-HSA-983170|dip:DIP-33189N|panther:PTHR19375(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/25	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:5303E6BF9EE3A02D|rigid:ijGbSaLCem4vq76DKLWO3FJrADA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14902	uniprotkb:Q5NHT8	intact:EBI-722083|uniprotkb:Q540B4|uniprotkb:E5RGR8|uniprotkb:F6M9T7|ensembl:ENSP00000430505.1|ensembl:ENSP00000430950.1	intact:EBI-2806309	psi-mi:i23o1_human(display_long)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)|uniprotkb:IDO1(gene name)|psi-mi:IDO1(display_short)|uniprotkb:IDO(gene name synonym)|uniprotkb:INDO(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298484|imex:IM-27563-25	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002155.1|ensembl:ENSG00000131203.13(gene)|ensembl:ENST00000518237.6(transcript)|ensembl:ENST00000522495.5(transcript)|go:""GO:0002666""(positive regulation of T cell tolerance induction)|go:""GO:0002678""(positive regulation of chronic inflammatory response)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0004833""(tryptophan 2,3-dioxygenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006569""(L-tryptophan catabolic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007565""(female pregnancy)|go:""GO:0009055""(electron transfer activity)|go:""GO:0019441""(L-tryptophan catabolic process to kynurenine)|go:""GO:0019805""(quinolinate biosynthetic process)|go:""GO:0020037""(heme binding)|go:""GO:0030485""(smooth muscle contractile fiber)|go:""GO:0032421""(stereocilium bundle)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032693""(negative regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0033555""(multicellular organismal response to stress)|go:""GO:0033754""(indoleamine 2,3-dioxygenase activity)|go:""GO:0034276""(kynurenic acid biosynthetic process)|go:""GO:0034354""('de novo' NAD biosynthetic process from L-tryptophan)|go:""GO:0036269""(swimming behavior)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0046872""(metal ion binding)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:0070234""(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|mint:P14902|rcsb pdb:2D0T|rcsb pdb:2D0U|rcsb pdb:4PK5|rcsb pdb:4PK6|rcsb pdb:4U72|rcsb pdb:4U74|rcsb pdb:5EK2|rcsb pdb:5EK3|rcsb pdb:5EK4|rcsb pdb:5ETW|rcsb pdb:5WHR|rcsb pdb:5WMU|rcsb pdb:5WMV|rcsb pdb:5WMW|rcsb pdb:5WMX|rcsb pdb:5WN8|rcsb pdb:5XE1|rcsb pdb:6AZU|rcsb pdb:6AZV|rcsb pdb:6AZW|rcsb pdb:6CXU|rcsb pdb:6CXV|rcsb pdb:6DPQ|rcsb pdb:6DPR|rcsb pdb:6E35|rcsb pdb:6E40|rcsb pdb:6E41|rcsb pdb:6E42|rcsb pdb:6E43|rcsb pdb:6E44|rcsb pdb:6E45|rcsb pdb:6E46|rcsb pdb:6F0A|rcsb pdb:6KOF|rcsb pdb:6KPS|rcsb pdb:6KW7|rcsb pdb:6MQ6|rcsb pdb:6O3I|rcsb pdb:6PU7|rcsb pdb:6PZ1|rcsb pdb:6R63|rcsb pdb:6UBP|rcsb pdb:6V52|rcsb pdb:6WJY|rcsb pdb:6WPE|rcsb pdb:6X5Y|rcsb pdb:7A62|rcsb pdb:7AH4|rcsb pdb:7AH5|rcsb pdb:7AH6|rcsb pdb:7B1O|rcsb pdb:7E0O|rcsb pdb:7E0P|rcsb pdb:7E0Q|rcsb pdb:7E0S|rcsb pdb:7E0T|rcsb pdb:7E0U|rcsb pdb:7M63|rcsb pdb:7M7D|rcsb pdb:7NGE|rcsb pdb:7P0N|rcsb pdb:7P0R|rcsb pdb:7RRB|rcsb pdb:7RRC|rcsb pdb:7RRD|rcsb pdb:7YXT|rcsb pdb:7Z2L|rcsb pdb:7ZV3|rcsb pdb:8ABX|rcsb pdb:8FUR|rcsb pdb:8I7L|reactome:R-HSA-71240|panther:PTHR28657(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:VRa+azotGbtrAaR03lR72aeUpGc9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:F8978CE3EC1FA7A0|rigid:AsGQLPIJ46Jk7gzsPT1FXm7ckeg	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14902	uniprotkb:Q5NEM9	intact:EBI-722083|uniprotkb:Q540B4|uniprotkb:E5RGR8|uniprotkb:F6M9T7|ensembl:ENSP00000430505.1|ensembl:ENSP00000430950.1	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:i23o1_human(display_long)|uniprotkb:Indoleamine-pyrrole 2,3-dioxygenase(gene name synonym)|uniprotkb:IDO1(gene name)|psi-mi:IDO1(display_short)|uniprotkb:IDO(gene name synonym)|uniprotkb:INDO(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298494|imex:IM-27563-485	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002155.1|ensembl:ENSG00000131203.13(gene)|ensembl:ENST00000518237.6(transcript)|ensembl:ENST00000522495.5(transcript)|go:""GO:0002666""(positive regulation of T cell tolerance induction)|go:""GO:0002678""(positive regulation of chronic inflammatory response)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0004833""(tryptophan 2,3-dioxygenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006569""(L-tryptophan catabolic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007565""(female pregnancy)|go:""GO:0009055""(electron transfer activity)|go:""GO:0019441""(L-tryptophan catabolic process to kynurenine)|go:""GO:0019805""(quinolinate biosynthetic process)|go:""GO:0020037""(heme binding)|go:""GO:0030485""(smooth muscle contractile fiber)|go:""GO:0032421""(stereocilium bundle)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032693""(negative regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0033555""(multicellular organismal response to stress)|go:""GO:0033754""(indoleamine 2,3-dioxygenase activity)|go:""GO:0034276""(kynurenic acid biosynthetic process)|go:""GO:0034354""('de novo' NAD biosynthetic process from L-tryptophan)|go:""GO:0036269""(swimming behavior)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0046872""(metal ion binding)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:0070234""(positive regulation of T cell apoptotic process)|interpro:IPR000898(Indoleamine 2,3-dioxygenase)|interpro:IPR037217|mint:P14902|rcsb pdb:2D0T|rcsb pdb:2D0U|rcsb pdb:4PK5|rcsb pdb:4PK6|rcsb pdb:4U72|rcsb pdb:4U74|rcsb pdb:5EK2|rcsb pdb:5EK3|rcsb pdb:5EK4|rcsb pdb:5ETW|rcsb pdb:5WHR|rcsb pdb:5WMU|rcsb pdb:5WMV|rcsb pdb:5WMW|rcsb pdb:5WMX|rcsb pdb:5WN8|rcsb pdb:5XE1|rcsb pdb:6AZU|rcsb pdb:6AZV|rcsb pdb:6AZW|rcsb pdb:6CXU|rcsb pdb:6CXV|rcsb pdb:6DPQ|rcsb pdb:6DPR|rcsb pdb:6E35|rcsb pdb:6E40|rcsb pdb:6E41|rcsb pdb:6E42|rcsb pdb:6E43|rcsb pdb:6E44|rcsb pdb:6E45|rcsb pdb:6E46|rcsb pdb:6F0A|rcsb pdb:6KOF|rcsb pdb:6KPS|rcsb pdb:6KW7|rcsb pdb:6MQ6|rcsb pdb:6O3I|rcsb pdb:6PU7|rcsb pdb:6PZ1|rcsb pdb:6R63|rcsb pdb:6UBP|rcsb pdb:6V52|rcsb pdb:6WJY|rcsb pdb:6WPE|rcsb pdb:6X5Y|rcsb pdb:7A62|rcsb pdb:7AH4|rcsb pdb:7AH5|rcsb pdb:7AH6|rcsb pdb:7B1O|rcsb pdb:7E0O|rcsb pdb:7E0P|rcsb pdb:7E0Q|rcsb pdb:7E0S|rcsb pdb:7E0T|rcsb pdb:7E0U|rcsb pdb:7M63|rcsb pdb:7M7D|rcsb pdb:7NGE|rcsb pdb:7P0N|rcsb pdb:7P0R|rcsb pdb:7RRB|rcsb pdb:7RRC|rcsb pdb:7RRD|rcsb pdb:7YXT|rcsb pdb:7Z2L|rcsb pdb:7ZV3|rcsb pdb:8ABX|rcsb pdb:8FUR|rcsb pdb:8I7L|reactome:R-HSA-71240|panther:PTHR28657(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:VRa+azotGbtrAaR03lR72aeUpGc9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:B74228666080A2BA|rigid:jsN5LU03+vxrzKwCPpvlFuBv4pM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11142	uniprotkb:Q5NG28	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378.3|ensembl:ENSP00000432083.1|ensembl:ENSP00000437125.1	intact:EBI-2802768|uniprotkb:A0A0G2RPI9	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)|uniprotkb:Heat shock protein family A member 8(gene name synonym)	psi-mi:q5ng28_fratt(display_long)|uniprotkb:dacD(gene name)|psi-mi:dacD(display_short)|uniprotkb:FTT_1029(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298464|imex:IM-27563-305	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006588.1|refseq:NP_694881.1|ensembl:ENSG00000109971.14(gene)|ensembl:ENST00000227378.7(transcript)|ensembl:ENST00000532636.5(transcript)|ensembl:ENST00000534624.6(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000974""(Prp19 complex)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042470""(melanosome)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055131""(C3HC4-type RING finger domain binding)|go:""GO:0061024""(membrane organization)|go:""GO:0061202""(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0061684""(chaperone-mediated autophagy)|go:""GO:0061740""(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0072318""(clathrin coat disassembly)|go:""GO:0072562""(blood microparticle)|go:""GO:0098575""(lumenal side of lysosomal membrane)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0140545""(ATP-dependent protein disaggregase activity)|go:""GO:0140597""(protein carrier chaperone)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|go:""GO:1902904""(negative regulation of supramolecular fiber organization)|go:""GO:1904589""(regulation of protein import)|go:""GO:1904764""(chaperone-mediated autophagy translocation complex disassembly)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9828642|reactome:R-HSA-9833482|refseq:XP_011541100.1|dip:DIP-32874N|panther:PTHR19375(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015956(Penicillin-binding protein-associated)|interpro:IPR018044|interpro:IPR012907(Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal)|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:YP_170014.1|refseq:WP_003021136.1|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|rcsb pdb:6OSU|mint:Q5NG28|interpro:IPR037167"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	rogid:EYTPcD8JUkej9Gvps0ogQD5aQ1c177416	intact-crc:F7CEE72DD416B4A2|rigid:thwK7cTOQvnZbEiZIm5trpZZ7Zs	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11142	uniprotkb:Q5NHH2	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378.3|ensembl:ENSP00000432083.1|ensembl:ENSP00000437125.1	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)|uniprotkb:Heat shock protein family A member 8(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298454|imex:IM-27563-23	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006588.1|refseq:NP_694881.1|ensembl:ENSG00000109971.14(gene)|ensembl:ENST00000227378.7(transcript)|ensembl:ENST00000532636.5(transcript)|ensembl:ENST00000534624.6(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000974""(Prp19 complex)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042470""(melanosome)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055131""(C3HC4-type RING finger domain binding)|go:""GO:0061024""(membrane organization)|go:""GO:0061202""(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0061684""(chaperone-mediated autophagy)|go:""GO:0061740""(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0072318""(clathrin coat disassembly)|go:""GO:0072562""(blood microparticle)|go:""GO:0098575""(lumenal side of lysosomal membrane)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0140545""(ATP-dependent protein disaggregase activity)|go:""GO:0140597""(protein carrier chaperone)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1900226""(negative regulation of NLRP3 inflammasome complex assembly)|go:""GO:1902904""(negative regulation of supramolecular fiber organization)|go:""GO:1904589""(regulation of protein import)|go:""GO:1904764""(chaperone-mediated autophagy translocation complex disassembly)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9828642|reactome:R-HSA-9833482|refseq:XP_011541100.1|dip:DIP-32874N|panther:PTHR19375(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:9F05A6689B4D9A0A|rigid:Ep8Ih3huLz5r1qBhTIPmGnPwhBY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16871	uniprotkb:Q5NE77	intact:EBI-80490|ensembl:ENSP00000306157.3|uniprotkb:Q6NSP4|uniprotkb:Q6SV45|uniprotkb:Q9UPC1|uniprotkb:B2RCS6|uniprotkb:Q6NWM0|uniprotkb:B4DVT1|uniprotkb:Q05CU8|uniprotkb:Q6NWM1|uniprotkb:Q6NWM2|uniprotkb:Q6NWM3	intact:EBI-22298544|uniprotkb:A0A0G2RPD5	psi-mi:il7ra_human(display_long)|uniprotkb:IL7R(gene name)|psi-mi:IL7R(display_short)|uniprotkb:CDw127(gene name synonym)	psi-mi:q5ne77_fratt(display_long)|uniprotkb:FTT_1776c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298552|imex:IM-27563-397	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168685.15(gene)|ensembl:ENST00000303115.8(transcript)|go:""GO:0000018""(regulation of DNA recombination)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0003823""(antigen binding)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0004917""(interleukin-7 receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010467""(gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019725""(cellular homeostasis)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033089""(positive regulation of T cell differentiation in thymus)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0042100""(B cell proliferation)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048535""(lymph node development)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:1904894""(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040997|mint:P16871|rcsb pdb:3DI2|rcsb pdb:3DI3|rcsb pdb:3UP1|rcsb pdb:5J11|rcsb pdb:6P50|rcsb pdb:6P67|rcsb pdb:7OPB|reactome:R-HSA-1266695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_002176.2|panther:PTHR23037(orthology-group)|efo:""Orphanet:169154""|efo:""Orphanet:39041""|dip:DIP-3045N|ensembl:ENSP00000306157.3|ensembl:ENST00000506850.5|ensembl:ENSP00000421207.1"	refseq:WP_003022749.1|refseq:YP_170665.1|interpro:IPR021952|mint:Q5NE77	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/06	rogid:8tfp5J+GYGrnzfuyfJhj8T+IMt89606	rogid:fk9hxhaOluvQGV8dWTKghUWTN14177416	intact-crc:C98F23123B05F2B7|rigid:eLOalkH/D3YQ7Jmi9NiimuEanXI	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16871	uniprotkb:Q5NIP8	intact:EBI-80490|ensembl:ENSP00000306157.3|uniprotkb:Q6NSP4|uniprotkb:Q6SV45|uniprotkb:Q9UPC1|uniprotkb:B2RCS6|uniprotkb:Q6NWM0|uniprotkb:B4DVT1|uniprotkb:Q05CU8|uniprotkb:Q6NWM1|uniprotkb:Q6NWM2|uniprotkb:Q6NWM3	intact:EBI-2796698	psi-mi:il7ra_human(display_long)|uniprotkb:IL7R(gene name)|psi-mi:IL7R(display_short)|uniprotkb:CDw127(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298534|imex:IM-27563-137	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168685.15(gene)|ensembl:ENST00000303115.8(transcript)|go:""GO:0000018""(regulation of DNA recombination)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0003823""(antigen binding)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0004917""(interleukin-7 receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010467""(gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019725""(cellular homeostasis)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033089""(positive regulation of T cell differentiation in thymus)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0042100""(B cell proliferation)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048535""(lymph node development)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:1904894""(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040997|mint:P16871|rcsb pdb:3DI2|rcsb pdb:3DI3|rcsb pdb:3UP1|rcsb pdb:5J11|rcsb pdb:6P50|rcsb pdb:6P67|rcsb pdb:7OPB|reactome:R-HSA-1266695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_002176.2|panther:PTHR23037(orthology-group)|efo:""Orphanet:169154""|efo:""Orphanet:39041""|dip:DIP-3045N|ensembl:ENSP00000306157.3|ensembl:ENST00000506850.5|ensembl:ENSP00000421207.1"	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/06	rogid:8tfp5J+GYGrnzfuyfJhj8T+IMt89606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:23F1892A91D490B7|rigid:1grjkP3A54HjMA55t1SoVOywP4Q	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13907	uniprotkb:Q5NES6	intact:EBI-6285983|uniprotkb:B4E155|uniprotkb:Q32Q13|uniprotkb:Q53GQ6|uniprotkb:Q86U81|uniprotkb:Q8WUX8|uniprotkb:Q96IZ4|uniprotkb:Q9BQ74|ensembl:ENSP00000401879.2	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:idi1_human(display_long)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:Isopentenyl pyrophosphate isomerase 1(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298474|imex:IM-27563-633	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004499.2|refseq:NP_001304884.1|refseq:NP_001304885.1|refseq:NP_001304886.1|refseq:XP_011517759.1|ensembl:ENSG00000067064.13(gene)|ensembl:ENST00000429642.2(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004452""(isopentenyl-diphosphate delta-isomerase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005829""(cytosol)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0008299""(isoprenoid biosynthetic process)|go:""GO:0009240""(isopentenyl diphosphate biosynthetic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0050992""(dimethylallyl diphosphate biosynthetic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR015797(NUDIX)|mint:Q13907|rcsb pdb:2DHO|rcsb pdb:2I6K|rcsb pdb:2ICJ|rcsb pdb:2ICK|reactome:R-HSA-191273|reactome:R-HSA-2426168|panther:PTHR10885(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:UbjHfBd6yrV1Gxv+R0z56N7DVgA9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:FB02C84626F18AA2|rigid:IOxUr75mY8P0pfwgTH0vvqZsyx4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:Q5NFP9	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298636|imex:IM-27563-491	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:2C39D18D4261FAD3|rigid:h+ovVZ2LLuQBXniSwX9Ebmc4bXM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZVL6	uniprotkb:Q5NIP8	intact:EBI-2320371|uniprotkb:B0QYU0|ensembl:ENSP00000315295.4	intact:EBI-2796698	psi-mi:k154l_human(display_long)|uniprotkb:KIAA1549L(gene name)|psi-mi:KIAA1549L(display_short)|uniprotkb:C11orf41(gene name synonym)|uniprotkb:C11orf69(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298626|imex:IM-27563-489	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011518271.1|refseq:NP_036326.2|ensembl:ENSG00000110427.17(gene)|ensembl:ENST00000321505.9(transcript)|go:""GO:0016020""(membrane)|interpro:IPR024606|mint:Q6ZVL6|panther:PTHR21590(orthology-group)"	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:ms/4igVx/iJRKbNf2+01PfpIWng9606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:B766569676CBAD5D|rigid:S+qbFovPRtYA4VHNs5TwA29GBQc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZI2	uniprotkb:Q5NGE3	intact:EBI-2120635|uniprotkb:Q5U822|uniprotkb:B7Z7B4|ensembl:ENSP00000395323.1|uniprotkb:Q3YAD2|uniprotkb:Q3YAD0|uniprotkb:Q3YAD1|uniprotkb:Q3YAD3|intact:EBI-12174367|uniprotkb:A0A0C4DFQ7	intact:EBI-22297821|uniprotkb:A0A0G2RPC6	psi-mi:kcip1_human(display_long)|uniprotkb:Kv channel-interacting protein 1(gene name synonym)|uniprotkb:KCNIP1(gene name)|psi-mi:KCNIP1(display_short)|uniprotkb:KCHIP1(gene name synonym)|uniprotkb:VABP(gene name synonym)|uniprotkb:Potassium channel-interacting protein 1(gene name synonym)|uniprotkb:Vesicle APC-binding protein(gene name synonym)	psi-mi:q5nge3_fratt(display_long)|uniprotkb:FTT_0902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298582|imex:IM-27563-487	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001030009.1|refseq:NP_055407.1|refseq:NP_001030010.1|refseq:NP_001265268.1|refseq:NP_001265269.1|refseq:XP_016864896.1|dip:DIP-29246N|ensembl:ENSG00000182132.15(gene)|ensembl:ENST00000411494.5(transcript)|go:""GO:0005267""(potassium channel activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006936""(muscle contraction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0008016""(regulation of heart contraction)|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0030425""(dendrite)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045202""(synapse)|go:""GO:0071196""(Kv4.3-KChIP1 channel complex)|go:""GO:0086009""(membrane repolarization)|go:""GO:0097623""(potassium ion export across plasma membrane)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:Q9NZI2|rcsb pdb:1S1E|rcsb pdb:2I2R|rcsb pdb:2NZ0|rcsb pdb:7E83|rcsb pdb:7E84|rcsb pdb:7F3F|rcsb pdb:7W6N|rcsb pdb:7W6T|reactome:R-HSA-5576894|panther:PTHR23055(orthology-group)"	refseq:YP_169899.1|mint:Q5NGE3	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:+4k81JjvVvA1ODWgsux/34foDFY9606	rogid:NCB/Hok6C9lpbhvu2mMcLmSbgZs177416	intact-crc:C9E8A264CD07D659|rigid:0L8jaPYoa6Q2jX+/4GYvQUEhVQA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5JSQ8	uniprotkb:Q5NHH2	intact:EBI-22298602|ensembl:ENSP00000359415.3|uniprotkb:E1P535	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:khdcl_human(display_long)|uniprotkb:KHDC1L(gene name)|psi-mi:KHDC1L(display_short)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298616|imex:IM-27563-31	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000256980.5(gene)|ensembl:ENST00000370388.4(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|interpro:IPR031952|interpro:IPR036612|mint:Q5JSQ8|panther:PTHR31368(orthology-group)|refseq:NP_001119535.1"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:N0hBD0JOu6iSeVwgbkxRu/lRIbU9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:760EDB4578302431|rigid:hSWFYlsf9XgLS+5leiKj8D9iTOk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZI2	uniprotkb:Q5NEQ5	intact:EBI-2120635|uniprotkb:Q5U822|uniprotkb:B7Z7B4|ensembl:ENSP00000395323.1|uniprotkb:Q3YAD2|uniprotkb:Q3YAD0|uniprotkb:Q3YAD1|uniprotkb:Q3YAD3|intact:EBI-12174367|uniprotkb:A0A0C4DFQ7	intact:EBI-2808269|uniprotkb:A0A0G2RQ71	psi-mi:kcip1_human(display_long)|uniprotkb:Kv channel-interacting protein 1(gene name synonym)|uniprotkb:KCNIP1(gene name)|psi-mi:KCNIP1(display_short)|uniprotkb:KCHIP1(gene name synonym)|uniprotkb:VABP(gene name synonym)|uniprotkb:Potassium channel-interacting protein 1(gene name synonym)|uniprotkb:Vesicle APC-binding protein(gene name synonym)	psi-mi:q5neq5_fratt(display_long)|uniprotkb:Polyphosphate kinase PPK2(gene name synonym)|uniprotkb:FTT_1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298592|imex:IM-27563-29	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001030009.1|refseq:NP_055407.1|refseq:NP_001030010.1|refseq:NP_001265268.1|refseq:NP_001265269.1|refseq:XP_016864896.1|dip:DIP-29246N|ensembl:ENSG00000182132.15(gene)|ensembl:ENST00000411494.5(transcript)|go:""GO:0005267""(potassium channel activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006936""(muscle contraction)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0008016""(regulation of heart contraction)|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0030425""(dendrite)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045202""(synapse)|go:""GO:0071196""(Kv4.3-KChIP1 channel complex)|go:""GO:0086009""(membrane repolarization)|go:""GO:0097623""(potassium ion export across plasma membrane)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:Q9NZI2|rcsb pdb:1S1E|rcsb pdb:2I2R|rcsb pdb:2NZ0|rcsb pdb:7E83|rcsb pdb:7E84|rcsb pdb:7F3F|rcsb pdb:7W6N|rcsb pdb:7W6T|reactome:R-HSA-5576894|panther:PTHR23055(orthology-group)"	"interpro:IPR016898(Polyphosphate kinase 2, predicted)|interpro:IPR022488|interpro:IPR022486|refseq:YP_170487.1|refseq:WP_003014894.1|interpro:IPR027417|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0046872""(metal ion binding)|rcsb pdb:4YEG|rcsb pdb:5LL0|rcsb pdb:5LLB|rcsb pdb:5LLF|mint:Q5NEQ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:+4k81JjvVvA1ODWgsux/34foDFY9606	rogid:3hIShFXVmkZdI9gV6zbu32j30jM177416	intact-crc:9FD84C0788785D63|rigid:rC31QoIQDNbkF4eRKMPePtrJMUQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:Q5NHH2	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298646|imex:IM-27563-33	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:70DBDB925C3695BE|rigid:KoYP3V4QENYzmdVsROwsZqqGDHM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:Q5NGE3	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-22297821|uniprotkb:A0A0G2RPC6	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:q5nge3_fratt(display_long)|uniprotkb:FTT_0902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298656|imex:IM-27563-567	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	refseq:YP_169899.1|mint:Q5NGE3	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:NCB/Hok6C9lpbhvu2mMcLmSbgZs177416	intact-crc:B3DACF7001D204E4|rigid:IBH7VxO97Sj7bFa5q4BUbdndTaI	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43657	uniprotkb:Q5NFP9	intact:EBI-2876949|ensembl:ENSP00000344353.2|ensembl:ENSP00000367691.3|ensembl:ENSP00000482660.1|uniprotkb:Q53FA0|uniprotkb:Q7Z3S0|uniprotkb:Q3KPF5|uniprotkb:Q5VW44|uniprotkb:O15133|uniprotkb:Q7Z3S6|uniprotkb:B3KVF2|uniprotkb:F2YGU4|uniprotkb:A4FTW9	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:lpar6_human(display_long)|uniprotkb:LPAR6(gene name)|psi-mi:LPAR6(display_short)|uniprotkb:P2RY5(gene name synonym)|uniprotkb:Oleoyl-L-alpha-lysophosphatidic acid receptor(gene name synonym)|uniprotkb:P2Y purinoceptor 5(gene name synonym)|uniprotkb:Purinergic receptor 5(gene name synonym)|uniprotkb:RB intron encoded G-protein coupled receptor(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298666|imex:IM-27563-637	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENST00000345941.2(transcript)|ensembl:ENSG00000139679.16(gene)|ensembl:ENST00000378434.8(transcript)|ensembl:ENST00000620633.5(transcript)|go:""GO:0001835""(blastocyst hatching)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0070915""(lysophosphatidic acid receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P43657|reactome:R-HSA-416476|reactome:R-HSA-417957|refseq:NP_001155969.1|refseq:NP_001155970.1|refseq:NP_005758.2|efo:""Orphanet:170""|efo:""Orphanet:55654""|panther:PTHR24232(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:P+X2vlEYWomdIDveBaFHGf5r2389606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:4DDB9A32B6A2F645|rigid:uFHlqNSJu1OVKf8WRl9ZMZwDC0Y	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y5V3	uniprotkb:Q5NFP9	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333.8|ensembl:ENSP00000364874.1|ensembl:ENSP00000364927.3	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298696|imex:IM-27563-399	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSG00000179222.18(gene)|ensembl:ENST00000326587.12(transcript)|ensembl:ENST00000375722.5(transcript)|ensembl:ENST00000375772.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0090190""(positive regulation of branching involved in ureteric bud morphogenesis)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:2001235""(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889|reactome:R-HSA-9768919|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|panther:PTHR11736(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:840EC29F74C257F9|rigid:R8TyDoyiNgFDRYLNfGWpxWDQwgI	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96S90	uniprotkb:Q5NGZ9	intact:EBI-10293291|uniprotkb:Q69YX9|uniprotkb:B4DQA1|ensembl:ENSP00000357904.5	intact:EBI-22297718|uniprotkb:A0A0G2RPD4	psi-mi:lysm1_human(display_long)|uniprotkb:LYSMD1(gene name)|psi-mi:LYSMD1(display_short)|uniprotkb:SB145(orf name)	psi-mi:q5ngz9_fratt(display_long)|uniprotkb:FTT_0677c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298686|imex:IM-27563-307	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001130015.1|refseq:NP_997716.1|ensembl:ENSG00000163155.12(gene)|ensembl:ENST00000368908.10(transcript)|go:""GO:0005654""(nucleoplasm)|interpro:IPR018392|interpro:IPR036779|interpro:IPR045030|mint:Q96S90|rcsb pdb:2DJP|panther:PTHR20932(orthology-group)"	"go:""GO:0008757""(S-adenosylmethionine-dependent methyltransferase activity)|go:""GO:0032259""(methylation)|interpro:IPR051052|refseq:YP_169693.1|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q5NGZ9|refseq:WP_003020462.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:bOg3ZT/SesaFiRNv0Djrp95rQSA9606	rogid:NsQTuFVA2+HfApHSBfsjyZCn664177416	intact-crc:A298F0FA324ECECA|rigid:Wf0WPVcFR5omQDsD8zLFPMpGM5g	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92604	uniprotkb:Q5NHH2	intact:EBI-6116942|uniprotkb:Q53YL2|ensembl:ENSP00000355963.1|ensembl:ENSP00000355964.4	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	"psi-mi:lgat1_human(display_long)|uniprotkb:2-acylglycerophosphocholine O-acyltransferase(gene name synonym)|uniprotkb:LPGAT1(gene name)|psi-mi:LPGAT1(display_short)|uniprotkb:FAM34A(gene name synonym)|uniprotkb:KIAA0205(gene name synonym)|uniprotkb:""Acyl-CoA:monoacylglycerol acyltransferase LPGAT1""(gene name synonym)|uniprotkb:Lysophospholipid acyltransferase 7(gene name synonym)|uniprotkb:""Stearoyl-CoA:1-lyso-2-acyl-PE acyltransferase""(gene name synonym)"	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298676|imex:IM-27563-35	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011508530.1|refseq:XP_011508531.1|refseq:NP_055688.1|refseq:NP_001307737.1|ensembl:ENSG00000123684.13(gene)|ensembl:ENST00000366996.1(transcript)|ensembl:ENST00000366997.9(transcript)|go:""GO:0003841""(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:""GO:0003846""(2-acylglycerol O-acyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0008654""(phospholipid biosynthetic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0019432""(triglyceride biosynthetic process)|go:""GO:0036148""(phosphatidylglycerol acyl-chain remodeling)|go:""GO:0036149""(phosphatidylinositol acyl-chain remodeling)|go:""GO:0036152""(phosphatidylethanolamine acyl-chain remodeling)|go:""GO:0045723""(positive regulation of fatty acid biosynthetic process)|go:""GO:0047144""(2-acylglycerol-3-phosphate O-acyltransferase activity)|go:""GO:0047190""(2-acylglycerophosphocholine O-acyltransferase activity)|go:""GO:0071617""(lysophospholipid acyltransferase activity)|go:""GO:0071618""(lysophosphatidylethanolamine acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR032098|mint:Q92604|reactome:R-HSA-1482925|panther:PTHR10983(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:9N2frmSoY9VESmi8Z3ERTo1L3CU9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:CCBDBD7B6EBBC4A9|rigid:vhwPaTNsbUAWQ8nu/LedcoXQitQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99747	uniprotkb:Q5NHH2	intact:EBI-3221833|uniprotkb:Q9BUV1|uniprotkb:B4DFC9|ensembl:ENSP00000324628.6	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:snag_human(display_long)|uniprotkb:NAPG(gene name)|psi-mi:NAPG(display_short)|uniprotkb:SNAPG(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein gamma(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298786|imex:IM-27563-39	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011524058.1|refseq:NP_003817.1|ensembl:ENSG00000134265.13(gene)|ensembl:ENST00000322897.11(transcript)|go:""GO:0005483""(soluble NSF attachment protein activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0019905""(syntaxin binding)|go:""GO:0031201""(SNARE complex)|go:""GO:0050821""(protein stabilization)|go:""GO:0061025""(membrane fusion)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q99747|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|panther:PTHR13768(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:QbHDxqDWn6/UYiMIOMiKfx5eCFg9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:79EF9807126A064A|rigid:b6YnNdTTCQfRPSrdSN2PBQhTbk8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6F6	uniprotkb:Q5NHT8	intact:EBI-1563108|uniprotkb:Q9UNY1|uniprotkb:B7Z3T4|uniprotkb:B7Z9A3|uniprotkb:F5H6A1|uniprotkb:J3KQZ7|uniprotkb:B7Z6I2|uniprotkb:Q17S00|uniprotkb:E9PQY6|ensembl:ENSP00000432436.1	intact:EBI-2806309	psi-mi:irag1_human(display_long)|uniprotkb:IRAG1(gene name)|psi-mi:IRAG1(display_short)|uniprotkb:IRAG(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate(gene name synonym)|uniprotkb:JAW1-related protein MRVI1(gene name synonym)|uniprotkb:JAW1L(gene name synonym)|uniprotkb:MRVI1(gene name synonym)|uniprotkb:Protein MRVI1(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298726|imex:IM-27563-141	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193809.1|refseq:NP_569056.4|refseq:NP_001092049.2|refseq:NP_001093633.1|refseq:NP_001093637.1|refseq:NP_001193810.1|panther:PTHR15352(orthology-group)|ensembl:ENSG00000072952.21(gene)|ensembl:ENST00000531107.5(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR008677(MRVI1)|mint:Q9Y6F6|reactome:R-HSA-418457"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:VcjVQPpBjKrNG6c94yC5WwitU2Y9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:1C0474F7C08A6525|rigid:xAem6CMedmvcsEtW4Ttc0s8vOZQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6F6	uniprotkb:Q5NHH2	intact:EBI-1563108|uniprotkb:Q9UNY1|uniprotkb:B7Z3T4|uniprotkb:B7Z9A3|uniprotkb:F5H6A1|uniprotkb:J3KQZ7|uniprotkb:B7Z6I2|uniprotkb:Q17S00|uniprotkb:E9PQY6|ensembl:ENSP00000432436.1	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:irag1_human(display_long)|uniprotkb:IRAG1(gene name)|psi-mi:IRAG1(display_short)|uniprotkb:IRAG(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate(gene name synonym)|uniprotkb:JAW1-related protein MRVI1(gene name synonym)|uniprotkb:JAW1L(gene name synonym)|uniprotkb:MRVI1(gene name synonym)|uniprotkb:Protein MRVI1(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298746|imex:IM-27563-37	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193809.1|refseq:NP_569056.4|refseq:NP_001092049.2|refseq:NP_001093633.1|refseq:NP_001093637.1|refseq:NP_001193810.1|panther:PTHR15352(orthology-group)|ensembl:ENSG00000072952.21(gene)|ensembl:ENST00000531107.5(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR008677(MRVI1)|mint:Q9Y6F6|reactome:R-HSA-418457"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:VcjVQPpBjKrNG6c94yC5WwitU2Y9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:3A10401669CE533D|rigid:KwhlwrDxz6KhFo2NVo22VhpzHZM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6F6	uniprotkb:Q5NEC5	intact:EBI-1563108|uniprotkb:Q9UNY1|uniprotkb:B7Z3T4|uniprotkb:B7Z9A3|uniprotkb:F5H6A1|uniprotkb:J3KQZ7|uniprotkb:B7Z6I2|uniprotkb:Q17S00|uniprotkb:E9PQY6|ensembl:ENSP00000432436.1	intact:EBI-22297545	psi-mi:irag1_human(display_long)|uniprotkb:IRAG1(gene name)|psi-mi:IRAG1(display_short)|uniprotkb:IRAG(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate(gene name synonym)|uniprotkb:JAW1-related protein MRVI1(gene name synonym)|uniprotkb:JAW1L(gene name synonym)|uniprotkb:MRVI1(gene name synonym)|uniprotkb:Protein MRVI1(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298756|imex:IM-27563-239	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193809.1|refseq:NP_569056.4|refseq:NP_001092049.2|refseq:NP_001093633.1|refseq:NP_001093637.1|refseq:NP_001193810.1|panther:PTHR15352(orthology-group)|ensembl:ENSG00000072952.21(gene)|ensembl:ENST00000531107.5(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR008677(MRVI1)|mint:Q9Y6F6|reactome:R-HSA-418457"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:VcjVQPpBjKrNG6c94yC5WwitU2Y9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:F285070D6EB95501|rigid:c/Qr8x0sAM3JYD2gtUGE9KsNVqY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6F6	uniprotkb:Q5NFP9	intact:EBI-1563108|uniprotkb:Q9UNY1|uniprotkb:B7Z3T4|uniprotkb:B7Z9A3|uniprotkb:F5H6A1|uniprotkb:J3KQZ7|uniprotkb:B7Z6I2|uniprotkb:Q17S00|uniprotkb:E9PQY6|ensembl:ENSP00000432436.1	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:irag1_human(display_long)|uniprotkb:IRAG1(gene name)|psi-mi:IRAG1(display_short)|uniprotkb:IRAG(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate(gene name synonym)|uniprotkb:JAW1-related protein MRVI1(gene name synonym)|uniprotkb:JAW1L(gene name synonym)|uniprotkb:MRVI1(gene name synonym)|uniprotkb:Protein MRVI1(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298736|imex:IM-27563-237	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193809.1|refseq:NP_569056.4|refseq:NP_001092049.2|refseq:NP_001093633.1|refseq:NP_001093637.1|refseq:NP_001193810.1|panther:PTHR15352(orthology-group)|ensembl:ENSG00000072952.21(gene)|ensembl:ENST00000531107.5(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR008677(MRVI1)|mint:Q9Y6F6|reactome:R-HSA-418457"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:VcjVQPpBjKrNG6c94yC5WwitU2Y9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:66F24A0977993C50|rigid:VWcKWH5MVQTxLU8zMMs6v4NsEuw	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99747	uniprotkb:Q5NEM9	intact:EBI-3221833|uniprotkb:Q9BUV1|uniprotkb:B4DFC9|ensembl:ENSP00000324628.6	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:snag_human(display_long)|uniprotkb:NAPG(gene name)|psi-mi:NAPG(display_short)|uniprotkb:SNAPG(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein gamma(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298796|imex:IM-27563-493	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011524058.1|refseq:NP_003817.1|ensembl:ENSG00000134265.13(gene)|ensembl:ENST00000322897.11(transcript)|go:""GO:0005483""(soluble NSF attachment protein activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006891""(intra-Golgi vesicle-mediated transport)|go:""GO:0019905""(syntaxin binding)|go:""GO:0031201""(SNARE complex)|go:""GO:0050821""(protein stabilization)|go:""GO:0061025""(membrane fusion)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q99747|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|panther:PTHR13768(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:QbHDxqDWn6/UYiMIOMiKfx5eCFg9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:102E086337B13548|rigid:gxiIO18EeHGrNdjg5vSlWJzPt+M	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BXW6	uniprotkb:Q5NHT8	intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|ensembl:ENSP00000320291.3|uniprotkb:B7Z7D3	intact:EBI-2806309	psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298856|imex:IM-27563-495	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|ensembl:ENSG00000141447.19(gene)|ensembl:ENST00000319481.8(transcript)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005768""(endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0044232""(organelle membrane contact site)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0120015""(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|rcsb pdb:8ZQ3|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881022.1|refseq:XP_016881023.1|panther:PTHR10972(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:979B173DC2C6E0B5|rigid:kcbLisSnhlNvOdbxkYGd6YSxB3E	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14786	uniprotkb:Q5NES6	intact:EBI-1187100|uniprotkb:O60461|uniprotkb:Q96IH5|uniprotkb:Q5T7F2|uniprotkb:Q5T7F3|uniprotkb:B0LPG9|uniprotkb:Q86T59|uniprotkb:Q5T7F1|uniprotkb:Q96I90|ensembl:ENSP00000265371.3|ensembl:ENSP00000364001.2	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:nrp1_human(display_long)|uniprotkb:Vascular endothelial cell growth factor 165 receptor(gene name synonym)|uniprotkb:NRP1(gene name)|psi-mi:NRP1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:VEGF165R(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298836|imex:IM-27563-309	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001019800.1|refseq:NP_001019799.1|refseq:NP_003864.4|panther:PTHR46806(orthology-group)|refseq:NP_001316997.1|dip:DIP-5743N|rcsb pdb:2QQN|ensembl:ENSG00000099250.18(gene)|ensembl:ENST00000265371.8(transcript)|ensembl:ENST00000374867.7(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001569""(branching involved in blood vessel morphogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001755""(neural crest cell migration)|go:""GO:0001764""(neuron migration)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002116""(semaphorin receptor complex)|go:""GO:0003148""(outflow tract septum morphogenesis)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005883""(neurofilament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007411""(axon guidance)|go:""GO:0007413""(axonal fasciculation)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008201""(heparin binding)|go:""GO:0009611""(response to wounding)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|rcsb pdb:3I97|go:""GO:0015026""(coreceptor activity)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0019838""(growth factor binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0021612""(facial nerve structural organization)|go:""GO:0021637""(trigeminal nerve structural organization)|go:""GO:0021649""(vestibulocochlear nerve structural organization)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021828""(gonadotrophin-releasing hormone neuronal migration to the hypothalamus)|go:""GO:0030424""(axon)|go:""GO:0030947""(regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031290""(retinal ganglion cell axon guidance)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032489""(regulation of Cdc42 protein signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035767""(endothelial cell chemotaxis)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0036486""(ventral trunk neural crest cell migration)|go:""GO:0038085""(vascular endothelial growth factor binding)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0038190""(VEGF-activated neuropilin signaling pathway)|go:""GO:0043005""(neuron projection)|go:""GO:0043235""(receptor complex)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048842""(positive regulation of axon extension involved in axon guidance)|go:""GO:0048843""(negative regulation of axon extension involved in axon guidance)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0048846""(axon extension involved in axon guidance)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0060385""(axonogenesis involved in innervation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0060666""(dichotomous subdivision of terminal units involved in salivary gland branching)|go:""GO:0060978""(angiogenesis involved in coronary vascular morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061299""(retina vasculature morphogenesis in camera-type eye)|go:""GO:0061441""(renal artery morphogenesis)|go:""GO:0061549""(sympathetic ganglion development)|go:""GO:0061551""(trigeminal ganglion development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071679""(commissural neuron axon guidance)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0097102""(endothelial tip cell fate specification)|go:""GO:0097374""(sensory neuron axon guidance)|go:""GO:0097443""(sorting endosome)|go:""GO:0097475""(motor neuron migration)|go:""GO:0097490""(sympathetic neuron projection extension)|go:""GO:0097491""(sympathetic neuron projection guidance)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099173""(postsynapse organization)|go:""GO:0150018""(basal dendrite development)|go:""GO:0150020""(basal dendrite arborization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1902946""(protein localization to early endosome)|go:""GO:1903375""(facioacoustic ganglion development)|go:""GO:1904835""(dorsal root ganglion morphogenesis)|go:""GO:1905040""(otic placode development)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000859(CUB)|interpro:IPR000998(MAM)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014648(Neuropilin)|interpro:IPR022579|interpro:IPR035914|interpro:IPR050633|mint:O14786|rcsb pdb:1KEX|rcsb pdb:2QQI|rcsb pdb:2QQM|rcsb pdb:4DEQ|rcsb pdb:4RN5|rcsb pdb:5C7G|rcsb pdb:5IJR|rcsb pdb:5IYY|rcsb pdb:5J1X|rcsb pdb:5JGI|rcsb pdb:5JGQ|rcsb pdb:5JHK|rcsb pdb:5L73|rcsb pdb:6FMC|rcsb pdb:6FMF|rcsb pdb:6TKK|rcsb pdb:7JJC|rcsb pdb:7O1N|rcsb pdb:7P5U|rcsb pdb:8C5G|rcsb pdb:8PFE|rcsb pdb:9EOU|reactome:R-HSA-194306|reactome:R-HSA-376176|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-445144|reactome:R-HSA-447041|reactome:R-HSA-9694614"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/27	rogid:q8i8R/AetWNGkscqBWAJPHhmF+E9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:1891EF5485F34699|rigid:YwyQtNtvBjFROqx4gOKEIk3DXHQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NBF2	uniprotkb:Q5NEC5	intact:EBI-10269163|ensembl:ENSP00000358307.3|uniprotkb:Q8N5A6|uniprotkb:Q8N1H1	intact:EBI-22297545	psi-mi:nhlc2_human(display_long)|uniprotkb:NHLRC2(gene name)|psi-mi:NHLRC2(display_short)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298826|imex:IM-27563-241	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000196865.4(gene)|ensembl:ENST00000369301.3(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0031093""(platelet alpha granule lumen)|interpro:IPR001258(NHL repeat)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR045302|mint:Q8NBF2|rcsb pdb:6G7W|rcsb pdb:6GC1|reactome:R-HSA-114608|refseq:NP_940916.2|efo:""Orphanet:621758""|panther:PTHR46388(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:l6KHp2SvEGlcQTQyNeZMA9sQvww9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:00C5AC1877C0DAEF|rigid:B8A0BPWh+MFax/qT+/JEwIs4cVA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0ZGT2	uniprotkb:Q5NHH2	intact:EBI-351705|uniprotkb:B4DPZ7|uniprotkb:A0PJ84|uniprotkb:Q0D2H2|uniprotkb:Q14CC2|uniprotkb:Q14CC3|uniprotkb:Q16081|uniprotkb:Q7Z2X0|uniprotkb:Q96DL0|uniprotkb:Q9Y2V1|intact:EBI-2555043|ensembl:ENSP00000333938.7	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:nexn_human(display_long)|uniprotkb:F-actin-binding protein(gene name synonym)|uniprotkb:Nelin(gene name synonym)|uniprotkb:NEXN(gene name)|psi-mi:NEXN(display_short)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298806|imex:IM-27563-41	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:154""|ensembl:ENSG00000162614.19(gene)|ensembl:ENST00000334785.12(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007411""(axon guidance)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030018""(Z disc)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0051015""(actin filament binding)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0070593""(dendrite self-avoidance)|go:""GO:0098632""(cell-cell adhesion mediator activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q0ZGT2|refseq:NP_001165780.1|refseq:NP_653174.3|refseq:XP_005271380.1|panther:PTHR10075(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:YtKRiGq1tjrPhdFzpS5TKVn3So89606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:92E56E3ADC1BA527|rigid:aErXgSOGMINH+88aodZpu+5X6Fk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3A3	uniprotkb:Q5NHT8	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|uniprotkb:B4DML0|ensembl:ENSP00000315702.4	intact:EBI-2806309	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298716|imex:IM-27563-235	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1|ensembl:ENSG00000115540.15(gene)|ensembl:ENST00000323303.9(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|panther:PTHR22599(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:50CF623508C009FF|rigid:ZgkR1jqhS2p/3mtV7OveinvwQVY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N573	uniprotkb:Q5NES6	intact:EBI-6137766|uniprotkb:A6NK11|uniprotkb:A8KA34|uniprotkb:B3KXL1|uniprotkb:B7Z402|uniprotkb:B7Z8N5|uniprotkb:D3HIS6|uniprotkb:Q3LIB5|uniprotkb:Q6ZVK9|uniprotkb:Q8N8V0|uniprotkb:Q9H266|uniprotkb:Q9NWC7|ensembl:ENSP00000405424.2	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:oxr1_human(display_long)|uniprotkb:OXR1(gene name)|psi-mi:OXR1(display_short)|uniprotkb:Nbla00307(orf name)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298866|imex:IM-27563-403	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001185461.1|refseq:NP_001185462.1|refseq:NP_001185463.1|refseq:NP_001185464.1|refseq:NP_060472.2|refseq:NP_851999.2|refseq:XP_016869083.1|ensembl:ENSG00000164830.19(gene)|ensembl:ENST00000442977.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007628""(adult walking behavior)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0071447""(cellular response to hydroperoxide)|go:""GO:1900408""(negative regulation of cellular response to oxidative stress)|go:""GO:1902083""(negative regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR006571(TLDc)|interpro:IPR018392|interpro:IPR036779|mint:Q8N573|panther:PTHR23354(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:GU3rsP6X4kRZtGK5LMEPLwZewxM9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:B77119D3B729C11F|rigid:EjZPpNK4lMV0X2zclOLZWTsSI0A	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZM1	uniprotkb:Q5NIP8	intact:EBI-1994363|ensembl:ENSP00000352208.4|uniprotkb:Q5VWW2|uniprotkb:Q5VWW3|uniprotkb:Q5VWW4|uniprotkb:Q5VWW5|uniprotkb:Q7Z642|uniprotkb:Q8IWH0|uniprotkb:Q9HBU3|uniprotkb:Q9NZM0|uniprotkb:Q9ULL3|uniprotkb:Q9Y4U4|uniprotkb:B3KQN5	intact:EBI-2796698	psi-mi:myof_human(display_long)|uniprotkb:MYOF(gene name)|psi-mi:MYOF(display_short)|uniprotkb:KIAA1207(gene name synonym)|uniprotkb:FER1L3(gene name synonym)|uniprotkb:Fer-1-like protein 3(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298766|imex:IM-27563-569	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000138119.17(gene)|ensembl:ENST00000359263.9(transcript)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0006936""(muscle contraction)|go:""GO:0008015""(blood circulation)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046928""(regulation of neurotransmitter secretion)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|interpro:IPR055072|mint:Q9NZM1|rcsb pdb:2DMH|rcsb pdb:2K2O|rcsb pdb:6EEL|refseq:NP_038479.1|refseq:NP_579899.1|panther:PTHR45911(orthology-group)|efo:""Orphanet:599418"""	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:YbWzqcootZO0/w6OLRqxZEEAu9U9606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:9296EE0F03C5BF56|rigid:UpZ3PCoUlBtaUabf4Qrx3ugl1io	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16236	uniprotkb:Q5NGJ5	intact:EBI-2007911|uniprotkb:Q53RW6|uniprotkb:Q59HH2|uniprotkb:Q96F71|uniprotkb:B2RBU2|uniprotkb:B4E338|uniprotkb:E9PGJ7|ensembl:ENSP00000380252.3|intact:EBI-28978278	intact:EBI-22297738|uniprotkb:A0A0G2RPF6	psi-mi:nf2l2_human(display_long)|uniprotkb:NFE2L2(gene name)|psi-mi:NFE2L2(display_short)|uniprotkb:NRF2(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 2(gene name synonym)	psi-mi:q5ngj5_fratt(display_long)|uniprotkb:FTT_0842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298816|imex:IM-27563-571	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:619979""|panther:PTHR24411(orthology-group)|dip:DIP-29971N|ensembl:ENSG00000116044.17(gene)|ensembl:ENST00000397062.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0010499""(proteasomal ubiquitin-independent protein catabolic process)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0036499""(PERK-mediated unfolded protein response)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045088""(regulation of innate immune response)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046223""(aflatoxin catabolic process)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0061431""(cellular response to methionine)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071280""(cellular response to copper ion)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071498""(cellular response to fluid shear stress)|go:""GO:0071499""(cellular response to laminar fluid shear stress)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0110076""(negative regulation of ferroptosis)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900038""(negative regulation of cellular response to hypoxia)|go:""GO:1900407""(regulation of cellular response to oxidative stress)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903788""(positive regulation of glutathione biosynthetic process)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904753""(negative regulation of vascular associated smooth muscle cell migration)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000121""(regulation of removal of superoxide radicals)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR047167|mint:Q16236|rcsb pdb:2FLU|rcsb pdb:2LZ1|rcsb pdb:3ZGC|rcsb pdb:4IFL|rcsb pdb:5WFV|rcsb pdb:6T7V|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2K|rcsb pdb:7O7B|rcsb pdb:7X5E|rcsb pdb:7X5F|rcsb pdb:7X5G|rcsb pdb:8EJR|rcsb pdb:8EJS|reactome:R-HSA-8951664|reactome:R-HSA-9679191|reactome:R-HSA-9707587|reactome:R-HSA-9707616|reactome:R-HSA-9755511|reactome:R-HSA-9759194|reactome:R-HSA-9762114|reactome:R-HSA-9818025|reactome:R-HSA-9818026|reactome:R-HSA-9818027|reactome:R-HSA-9818028|reactome:R-HSA-9818030|reactome:R-HSA-9818032|reactome:R-HSA-9818035|reactome:R-HSA-9818749|refseq:NP_001138884.1|refseq:NP_001138885.1|refseq:NP_001300829.1|refseq:NP_001300830.1|refseq:NP_006155.2"	"go:""GO:0009279""(cell outer membrane)|interpro:IPR050330|refseq:WP_003020808.1|refseq:YP_169847.1|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|mint:Q5NGJ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/20	rogid:EjSeL1dJClhC2vIPip6QDc8QAUk9606	rogid:/Dq7r5H2A4RbaDlrrHYQHMOGtbc177416	intact-crc:7BB40F0FD26B449C|rigid:rzxAKBfwAAz2ZCeyq6QFkuHp6Zw	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00439	uniprotkb:Q5NEC5	intact:EBI-2861444|uniprotkb:Q16717|uniprotkb:Q8TC14|ensembl:ENSP00000448059.1	intact:EBI-22297545	psi-mi:ph4h_human(display_long)|uniprotkb:PAH(gene name)|psi-mi:PAH(display_short)|uniprotkb:Phe-4-monooxygenase(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298876|imex:IM-27563-639	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-58927N|ensembl:ENSG00000171759.10(gene)|ensembl:ENST00000553106.6(transcript)|go:""GO:0004505""(phenylalanine 4-monooxygenase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006559""(L-phenylalanine catabolic process)|go:""GO:0006571""(tyrosine biosynthetic process)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0042423""(catecholamine biosynthetic process)|interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR005961(Phenylalanine-4-hydroxylase, tetrameric form)|interpro:IPR018301|interpro:IPR019773|interpro:IPR019774|interpro:IPR036329|interpro:IPR036951|interpro:IPR041912|interpro:IPR045865|mint:P00439|rcsb pdb:1DMW|rcsb pdb:1J8T|rcsb pdb:1J8U|rcsb pdb:1KW0|rcsb pdb:1LRM|rcsb pdb:1MMK|rcsb pdb:1MMT|rcsb pdb:1PAH|rcsb pdb:1TDW|rcsb pdb:1TG2|rcsb pdb:2PAH|rcsb pdb:3PAH|rcsb pdb:4ANP|rcsb pdb:4PAH|rcsb pdb:5FII|rcsb pdb:5PAH|rcsb pdb:6HPO|rcsb pdb:6HYC|rcsb pdb:6N1K|rcsb pdb:6PAH|reactome:R-HSA-2160456|reactome:R-HSA-8964208|refseq:NP_000268.1|efo:""Orphanet:2209""|efo:""Orphanet:293284""|efo:""Orphanet:79253""|efo:""Orphanet:79254""|efo:""Orphanet:79651""|panther:PTHR11473(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:byO1PdD6RTWtUZOt5A9/N/Gl4Do9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:98C9EC6EC403D5D8|rigid:iD8B5riVwlAu/8iN0BPLZJvevVU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15648	uniprotkb:Q5NEQ5	intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651.6	intact:EBI-2808269|uniprotkb:A0A0G2RQ71	psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym)	psi-mi:q5neq5_fratt(display_long)|uniprotkb:Polyphosphate kinase PPK2(gene name synonym)|uniprotkb:FTT_1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298706|imex:IM-27563-139	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004765.2|ensembl:ENSG00000125686.12(gene)|ensembl:ENST00000300651.11(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000785""(chromatin)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001889""(liver development)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0002088""(lens development in camera-type eye)|go:""GO:0002154""(thyroid hormone receptor signaling pathway)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003406""(retinal pigment epithelium development)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006590""(thyroid hormone generation)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006702""(androgen biosynthetic process)|go:""GO:0007420""(brain development)|go:""GO:0007595""(lactation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010839""(negative regulation of keratinocyte proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030518""(nuclear receptor-mediated steroid hormone signaling pathway)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0033148""(positive regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0035035""(histone acetyltransferase binding)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035162""(embryonic hemopoiesis)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0042975""(peroxisome proliferator activated receptor binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045023""(G0 to G1 transition)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048821""(erythrocyte development)|go:""GO:0048822""(enucleate erythrocyte development)|go:""GO:0050693""(LBD domain binding)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0060335""(positive regulation of type II interferon-mediated signaling pathway)|go:""GO:0060744""(mammary gland branching involved in thelarche)|go:""GO:0060745""(mammary gland branching involved in pregnancy)|go:""GO:0060750""(epithelial cell proliferation involved in mammary gland duct elongation)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070318""(positive regulation of G0 to G1 transition)|go:""GO:0070562""(regulation of vitamin D receptor signaling pathway)|go:""GO:0070847""(core mediator complex)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0097067""(cellular response to thyroid hormone stimulus)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000347""(positive regulation of hepatocyte proliferation)|go:""GO:2001141""(regulation of RNA biosynthetic process)|interpro:IPR019680|interpro:IPR051999|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7OXU|rcsb pdb:7VQP|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9833110|reactome:R-HSA-9841922|dip:DIP-24212N|panther:PTHR12881(orthology-group)"	"interpro:IPR016898(Polyphosphate kinase 2, predicted)|interpro:IPR022488|interpro:IPR022486|refseq:YP_170487.1|refseq:WP_003014894.1|interpro:IPR027417|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0046872""(metal ion binding)|rcsb pdb:4YEG|rcsb pdb:5LL0|rcsb pdb:5LLB|rcsb pdb:5LLF|mint:Q5NEQ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/17	rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606	rogid:3hIShFXVmkZdI9gV6zbu32j30jM177416	intact-crc:23D4C6FE4E4B0ED2|rigid:ixRLLVmK0LSlLqffSY3ojtppV+g	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92802	uniprotkb:Q5NFP9	intact:EBI-2514973|uniprotkb:A3KME8|ensembl:ENSP00000267068.3|ensembl:ENSP00000501416.1|ensembl:ENSP00000501516.1|ensembl:ENSP00000501518.1|ensembl:ENSP00000501537.1	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:n42l2_human(display_long)|uniprotkb:N4BP2L2(gene name)|psi-mi:N4BP2L2(display_short)|uniprotkb:CG005(gene name synonym)|uniprotkb:PFAAP5(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 5(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298776|imex:IM-27563-401	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_016875836.1|refseq:XP_016875837.1|refseq:XP_016875838.1|refseq:NP_055702.1|ensembl:ENSG00000244754.9(gene)|ensembl:ENST00000267068.6(transcript)|ensembl:ENST00000674349.1(transcript)|ensembl:ENST00000674421.1(transcript)|ensembl:ENST00000674465.1(transcript)|ensembl:ENST00000674484.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001824""(blastocyst development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019899""(enzyme binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902035""(positive regulation of hematopoietic stem cell proliferation)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|interpro:IPR026302|interpro:IPR027417|mint:Q92802|panther:PTHR13308(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:a7wRNCzoB/ImcDT7U8E5355qX1A9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:5184C1FC560AEC97|rigid:5UqW6FldOaugbK+6ybomvd9Jzes	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49757	uniprotkb:Q5NEM9	intact:EBI-915016|uniprotkb:Q6NUQ7|uniprotkb:Q86SY1|uniprotkb:Q8WW73|uniprotkb:Q9UBG1|uniprotkb:Q9UEQ4|uniprotkb:Q9UKE8|uniprotkb:Q9UKE9|uniprotkb:Q9UKF0|uniprotkb:Q9UQJ4|uniprotkb:B4E2B1|ensembl:ENSP00000347169.3|ensembl:ENSP00000451300.1|uniprotkb:B1P2N7|uniprotkb:B1P2N8|uniprotkb:B1P2N9|uniprotkb:B1P2N5|uniprotkb:B1P2N6|intact:EBI-28966915	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:numb_human(display_long)|uniprotkb:Protein S171(gene name synonym)|uniprotkb:NUMB(gene name)|psi-mi:NUMB(display_short)|uniprotkb:C14orf41(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298846|imex:IM-27563-143	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001307043.1|refseq:NP_001005743.1|refseq:NP_001005744.1|refseq:NP_001005745.1|refseq:NP_003735.3|ensembl:ENSG00000133961.22(gene)|ensembl:ENST00000355058.7(transcript)|ensembl:ENST00000555238.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005925""(focal adhesion)|go:""GO:0007409""(axonogenesis)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0010008""(endosome membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0021670""(lateral ventricle development)|go:""GO:0021849""(neuroblast division in subventricular zone)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034332""(adherens junction organization)|go:""GO:0045177""(apical part of cell)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P49757|rcsb pdb:5NJJ|rcsb pdb:5NJK|reactome:R-HSA-2122948|reactome:R-HSA-437239|reactome:R-HSA-5610780|reactome:R-HSA-5632684|reactome:R-HSA-9725554|dip:DIP-37981N|panther:PTHR47368(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/28	rogid:X+CHBhp67o6ROnf86RCtXlCAaF49606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:ED5616F324F9C372|rigid:UEh/wdrA6HP08fSbluYHezdH/aw	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P52434	uniprotkb:Q5NHT8	intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8|ensembl:ENSP00000392913.1	intact:EBI-2806309	psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298976|imex:IM-27563-407	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006223.2|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|ensembl:ENSG00000163882.10(gene)|ensembl:ENST00000456318.6(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005665""(RNA polymerase II, core complex)|go:""GO:0005666""(RNA polymerase III complex)|go:""GO:0005736""(RNA polymerase I complex)|go:""GO:0005829""(cytosol)|go:""GO:0006360""(transcription by RNA polymerase I)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006383""(transcription by RNA polymerase III)|go:""GO:0032993""(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7FJI|rcsb pdb:7FJJ|rcsb pdb:7LBM|rcsb pdb:7OB9|rcsb pdb:7OBA|rcsb pdb:7OBB|rcsb pdb:7VBA|rcsb pdb:7VBB|rcsb pdb:7VBC|rcsb pdb:8A43|rcsb pdb:8ITY|rcsb pdb:8IUE|rcsb pdb:8IUH|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N|panther:PTHR10917(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/27	rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:0A337052D0DE3831|rigid:IiIyxO2TtZw3eTMxyvg4BKZPXwY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NDX5	uniprotkb:Q5NFP9	intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271.1	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298936|imex:IM-27563-145	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSG00000173889.16(gene)|ensembl:ENST00000494943.5(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0042393""(histone binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|interpro:IPR050548|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|panther:PTHR12247(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:CDF73C61B2008516|rigid:wAIbsui2VnzC1Gh6vCRu/c60GLk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NDX5	uniprotkb:Q5NES6	intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271.1	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298946|imex:IM-27563-147	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSG00000173889.16(gene)|ensembl:ENST00000494943.5(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0042393""(histone binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|interpro:IPR050548|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|panther:PTHR12247(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:53BF4037FD42FC53|rigid:/RB0FCg/TZkEbBIUEbGcidq+ZrA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WX93	uniprotkb:Q5NFP9	intact:EBI-2803991|uniprotkb:Q9Y2J6|uniprotkb:Q9UQF5|uniprotkb:Q8N1M2|uniprotkb:Q7Z3W0|uniprotkb:Q86WE8|uniprotkb:B5MD56|uniprotkb:Q7L3E0|uniprotkb:Q9UGA0|uniprotkb:Q9Y3E9|uniprotkb:B7ZMM5|uniprotkb:B3KTG2	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:palld_human(display_long)|uniprotkb:KIAA0992(gene name synonym)|uniprotkb:SIH002(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-77(gene name synonym)|uniprotkb:CGI-151(orf name)|uniprotkb:PALLD(gene name)|psi-mi:PALLD(display_short)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298886|imex:IM-27563-311	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0002102""(podosome)|go:""GO:0003334""(keratinocyte development)|go:""GO:0003382""(epithelial cell morphogenesis)|go:""GO:0003779""(actin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007411""(axon guidance)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016477""(cell migration)|go:""GO:0030018""(Z disc)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030424""(axon)|go:""GO:0030426""(growth cone)|go:""GO:0051371""(muscle alpha-actinin binding)|go:""GO:0060076""(excitatory synapse)|go:""GO:0070593""(dendrite self-avoidance)|go:""GO:0098632""(cell-cell adhesion mediator activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033017|interpro:IPR036179|mint:Q8WX93|rcsb pdb:2DM2|rcsb pdb:2DM3|refseq:NP_001159580.1|refseq:NP_001159581.1|refseq:NP_001159582.1|refseq:NP_057165.3|efo:""Orphanet:1333""|panther:PTHR10075(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:0GUVyoDYzf03b+bZXUa1n/fnP/Y9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:0D1596CFA71118D9|rigid:ky+Y5J9jfoj18pvXESY9evjf6Ms	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z4L9	uniprotkb:Q5NHH2	intact:EBI-20861779|uniprotkb:G3V118|ensembl:ENSP00000429721.1	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:ppr42_human(display_long)|uniprotkb:Leucine-rich repeat-containing protein 67(gene name synonym)|uniprotkb:PPP1R42(gene name)|psi-mi:PPP1R42(display_short)|uniprotkb:LRRC67(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299034|imex:IM-27563-151	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001013648.1|refseq:NP_001335492.1|panther:PTHR45973(orthology-group)|ensembl:ENSG00000178125.15(gene)|ensembl:ENST00000522909.5(transcript)|go:""GO:0002177""(manchette)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015631""(tubulin binding)|go:""GO:0070840""(dynein complex binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|interpro:IPR050836|mint:Q7Z4L9"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:Yz6kBX8B96wPZIccbK+NXyae12g9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:D8455844C5859F43|rigid:s0soh4+hPA+vxutpYg+Mr1gh/Ag	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63098	uniprotkb:Q5NEQ5	intact:EBI-915984|uniprotkb:B5MDU4|uniprotkb:P06705|uniprotkb:P15117|uniprotkb:Q08044|uniprotkb:Q53SL0|uniprotkb:B2RC10|ensembl:ENSP00000234310.3	intact:EBI-2808269|uniprotkb:A0A0G2RQ71	psi-mi:canb1_human(display_long)|uniprotkb:PPP3R1(gene name)|psi-mi:PPP3R1(display_short)|uniprotkb:CNA2(gene name synonym)|uniprotkb:CNB(gene name synonym)|uniprotkb:Protein phosphatase 2B regulatory subunit 1(gene name synonym)|uniprotkb:Protein phosphatase 3 regulatory subunit B alpha isoform 1(gene name synonym)	psi-mi:q5neq5_fratt(display_long)|uniprotkb:Polyphosphate kinase PPK2(gene name synonym)|uniprotkb:FTT_1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299044|imex:IM-27563-153	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000936.1|ensembl:ENSG00000221823.11(gene)|ensembl:ENST00000234310.8(transcript)|go:""GO:0001569""(branching involved in blood vessel morphogenesis)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0004723""(calcium-dependent protein serine/threonine phosphatase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005955""(calcineurin complex)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007507""(heart development)|go:""GO:0008287""(protein serine/threonine phosphatase complex)|go:""GO:0008597""(calcium-dependent protein serine/threonine phosphatase regulator activity)|go:""GO:0019902""(phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022011""(myelination in peripheral nervous system)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0042383""(sarcolemma)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0060487""(lung epithelial cell differentiation)|go:""GO:0070886""(positive regulation of calcineurin-NFAT signaling cascade)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098688""(parallel fiber to Purkinje cell synapse)|go:""GO:0098693""(regulation of synaptic vesicle cycle)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:0099170""(postsynaptic modulation of chemical synaptic transmission)|go:""GO:1905665""(positive regulation of calcium ion import across plasma membrane)|go:""GO:1905949""(negative regulation of calcium ion import across plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P63098|rcsb pdb:1AUI|rcsb pdb:1M63|rcsb pdb:1MF8|rcsb pdb:2P6B|rcsb pdb:3LL8|rcsb pdb:4F0Z|rcsb pdb:4OR9|rcsb pdb:4ORA|rcsb pdb:4ORC|rcsb pdb:5SVE|rcsb pdb:6NUC|rcsb pdb:6NUF|rcsb pdb:6NUU|rcsb pdb:7U0T|rcsb pdb:9B9G|reactome:R-HSA-111447|reactome:R-HSA-180024|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763|dip:DIP-6096N|panther:PTHR45942(orthology-group)"	"interpro:IPR016898(Polyphosphate kinase 2, predicted)|interpro:IPR022488|interpro:IPR022486|refseq:YP_170487.1|refseq:WP_003014894.1|interpro:IPR027417|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0046872""(metal ion binding)|rcsb pdb:4YEG|rcsb pdb:5LL0|rcsb pdb:5LLB|rcsb pdb:5LLF|mint:Q5NEQ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/27	rogid:RqM4Q9x8EiLx7CyoF2Rvjl5RddM9606	rogid:3hIShFXVmkZdI9gV6zbu32j30jM177416	intact-crc:5A2B868645D9ADD8|rigid:GJrvh76CVdpRD5ZHQkYYFt5qZkA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NVD7	uniprotkb:Q5NHH2	intact:EBI-747655|uniprotkb:Q96C85|uniprotkb:Q9HA48|ensembl:ENSP00000334008.9	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:parva_human(display_long)|uniprotkb:Calponin-like integrin-linked kinase-binding protein(gene name synonym)|uniprotkb:CH-ILKBP(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 2(gene name synonym)|uniprotkb:Actopaxin(gene name synonym)|uniprotkb:PARVA(gene name)|psi-mi:PARVA(display_short)|uniprotkb:MXRA2(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298896|imex:IM-27563-313	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060692.2|ensembl:ENSG00000197702.14(gene)|ensembl:ENST00000334956.15(transcript)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003148""(outflow tract septum morphogenesis)|go:""GO:0003779""(actin binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030018""(Z disc)|go:""GO:0030027""(lamellipodium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0045296""(cadherin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0060271""(cilium assembly)|go:""GO:0070252""(actin-mediated cell contraction)|go:""GO:0071670""(smooth muscle cell chemotaxis)|go:""GO:0071963""(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9NVD7|rcsb pdb:2K2R|rcsb pdb:2VZC|rcsb pdb:2VZD|rcsb pdb:2VZG|rcsb pdb:2VZI|rcsb pdb:3KMU|rcsb pdb:3KMW|rcsb pdb:3REP|rcsb pdb:6MIB|reactome:R-HSA-446343|reactome:R-HSA-446353|reactome:R-HSA-446388|panther:PTHR12114(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/17	rogid:KjiRqYX7cAl33+lH1FnFGfkaZsM9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:A652914E72F75F5F|rigid:IWDVmwLKp+hR2/FudQebPNjBoxU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15120	uniprotkb:Q5NEC5	intact:EBI-1383915|uniprotkb:B4DXG6|ensembl:ENSP00000368460.4|ensembl:ENSP00000497727.1	intact:EBI-22297545	psi-mi:pdk3_human(display_long)|uniprotkb:Pyruvate dehydrogenase kinase isoform 3(gene name synonym)|uniprotkb:PDK3(gene name)|psi-mi:PDK3(display_short)|uniprotkb:PDHK3(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298916|imex:IM-27563-243	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-29498N|ensembl:ENSG00000067992.17(gene)|ensembl:ENST00000379162.9(transcript)|ensembl:ENST00000648777.1(transcript)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004740""(""pyruvate dehydrogenase (acetyl-transferring) kinase activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0010510""(regulation of acetyl-CoA biosynthetic process from pyruvate)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071398""(cellular response to fatty acid)|go:""GO:0097411""(hypoxia-inducible factor-1alpha signaling pathway)|go:""GO:2000377""(regulation of reactive oxygen species metabolic process)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:Q15120|rcsb pdb:1Y8N|rcsb pdb:1Y8O|rcsb pdb:1Y8P|rcsb pdb:2PNR|rcsb pdb:2Q8I|reactome:R-HSA-204174|reactome:R-HSA-5362517|refseq:NP_001135858.1|refseq:NP_005382.1|panther:PTHR11947(orthology-group)|efo:""Orphanet:352675"""	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/26	rogid:Q+/L48rFsQ7HDy8zDZWSfHzVghU9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:1B8BE9FD92F08883|rigid:Du8gVZaE6PLcXajnP+6yCsQmqDc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96FC7	uniprotkb:Q5NES6	intact:EBI-748888|uniprotkb:Q68DF3|uniprotkb:Q6UXY3|uniprotkb:Q8N3W3|uniprotkb:Q96JM9|uniprotkb:Q96NP7|uniprotkb:B7WP61|ensembl:ENSP00000362987.4	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:phipl_human(display_long)|uniprotkb:PHYHIPL(gene name)|psi-mi:PHYHIPL(display_short)|uniprotkb:KIAA1796(gene name synonym)|uniprotkb:UNQ6309/PRO20934(orf name)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298956|imex:IM-27563-245	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137246.1|refseq:NP_115815.2|ensembl:ENSG00000165443.12(gene)|ensembl:ENST00000373880.9(transcript)|go:""GO:0005737""(cytoplasm)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR042868|interpro:IPR045545|mint:Q96FC7|panther:PTHR15698(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:UN1Behcm7/kY5U0oV5EiZfMgRW89606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:550B828E3256E0A0|rigid:9qbGjhQaELx7xKjPOhAOuOfTH48	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A8MPX8	uniprotkb:Q5NEC5	intact:EBI-22298996|ensembl:ENSP00000373702.4|uniprotkb:Q96LI7	intact:EBI-22297545	psi-mi:pp2d1_human(display_long)|uniprotkb:PP2D1(gene name)|psi-mi:PP2D1(display_short)|uniprotkb:C3orf48(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299014|imex:IM-27563-149	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000183977.14(gene)|ensembl:ENST00000389050.5(transcript)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0007165""(signal transduction)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:A8MPX8|panther:PTHR13832(orthology-group)|refseq:NP_001239586.1"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/15	rogid:2x7dQmQ6NqT852UgYibQtjw96JI9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:6CE29B71F1ECD487|rigid:qV6x7SNRyE/RIctQhFyVihV+dTI	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TCG2	uniprotkb:Q5NES6	intact:EBI-2116334|uniprotkb:Q9NUW2|ensembl:ENSP00000264864.6	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:p4k2b_human(display_long)|uniprotkb:PI4K2B(gene name)|psi-mi:PI4K2B(display_short)|uniprotkb:Phosphatidylinositol 4-kinase type II-beta(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298966|imex:IM-27563-43	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060793.2|panther:PTHR12865(orthology-group)|ensembl:ENSG00000038210.14(gene)|ensembl:ENST00000264864.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004430""(1-phosphatidylinositol 4-kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0007030""(Golgi organization)|go:""GO:0007032""(endosome organization)|go:""GO:0016020""(membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR039756|mint:Q8TCG2|rcsb pdb:4WTV|rcsb pdb:8A5X|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:hUI49lg+0Pgm1FdMiZsg40z/AZw9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:FDCC9FCE17905FD9|rigid:xgpXV12whyE7o3+NC3Rab8ONOOs	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P60484	uniprotkb:Q5NEC5	intact:EBI-696162|uniprotkb:O00633|uniprotkb:O02679|uniprotkb:Q6ICT7|uniprotkb:B2R904|ensembl:ENSP00000361021.3|ensembl:ENSP00000494918.2|ensembl:ENSP00000508752.1|ensembl:ENSP00000518242.1|uniprotkb:F2YHV0	intact:EBI-22297545	psi-mi:pten_human(display_long)|uniprotkb:Phosphatase and tensin homolog(gene name synonym)|uniprotkb:Mutated in multiple advanced cancers 1(gene name synonym)|uniprotkb:PTEN(gene name)|psi-mi:PTEN(display_short)|uniprotkb:MMAC1(gene name synonym)|uniprotkb:TEP1(gene name synonym)|uniprotkb:Inositol polyphosphate 3-phosphatase(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299074|imex:IM-27563-643	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000171862.16(gene)|ensembl:ENSG00000284792.2(gene)|ensembl:ENST00000371953.8(transcript)|ensembl:ENST00000644628.2(transcript)|ensembl:ENST00000688308.1(transcript)|ensembl:ENST00000710385.1(transcript)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0004438""(phosphatidylinositol-3-phosphate phosphatase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0007056""(spindle assembly involved in female meiosis)|go:""GO:0007270""(neuron-neuron synaptic transmission)|go:""GO:0007416""(synapse assembly)|go:""GO:0007417""(central nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0007611""(learning or memory)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008289""(lipid binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0010997""(anaphase-promoting complex binding)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016314""(phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0016605""(PML body)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0021542""(dentate gyrus development)|go:""GO:0021955""(central nervous system neuron axonogenesis)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030351""(inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity)|go:""GO:0030534""(adult behavior)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032286""(central nervous system myelin maintenance)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0033555""(multicellular organismal response to stress)|go:""GO:0035176""(social behavior)|go:""GO:0035749""(myelin sheath adaxonal region)|go:""GO:0042711""(maternal behavior)|go:""GO:0042802""(identical protein binding)|go:""GO:0042995""(cell projection)|go:""GO:0043005""(neuron projection)|go:""GO:0043197""(dendritic spine)|go:""GO:0043220""(Schmidt-Lanterman incisure)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045736""(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046621""(negative regulation of organ growth)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|go:""GO:0048853""(forebrain morphogenesis)|go:""GO:0048870""(cell motility)|go:""GO:0050771""(negative regulation of axonogenesis)|go:""GO:0050821""(protein stabilization)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051548""(negative regulation of keratinocyte migration)|go:""GO:0051717""(inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity)|go:""GO:0051800""(phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity)|go:""GO:0051895""(negative regulation of focal adhesion assembly)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0052866""(phosphatidylinositol phosphate phosphatase activity)|go:""GO:0060024""(rhythmic synaptic transmission)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060074""(synapse maturation)|go:""GO:0060134""(prepulse inhibition)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0071257""(cellular response to electrical stimulus)|go:""GO:0090394""(negative regulation of excitatory postsynaptic potential)|go:""GO:0097105""(presynaptic membrane assembly)|go:""GO:0097107""(postsynaptic density assembly)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1902807""(negative regulation of cell cycle G1/S phase transition)|go:""GO:1903690""(negative regulation of wound healing, spreading of epidermal cells)|go:""GO:1904668""(positive regulation of ubiquitin protein ligase activity)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990381""(ubiquitin-specific protease binding)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|go:""GO:1990757""(ubiquitin ligase activator activity)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000463""(positive regulation of excitatory postsynaptic potential)|go:""GO:2000773""(negative regulation of cellular senescence)|go:""GO:2000808""(negative regulation of synaptic vesicle clustering)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR014020(C2 tensin-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017361(Bifunctional phosphatidylinositol trisphosphate phosphatase/dual-specificity phosphatase PTEN)|interpro:IPR029021|interpro:IPR029023|interpro:IPR035892|interpro:IPR045101|interpro:IPR051281|mint:P60484|rcsb pdb:1D5R|rcsb pdb:2KYL|rcsb pdb:4O1V|rcsb pdb:5BUG|rcsb pdb:5BZX|rcsb pdb:5BZZ|rcsb pdb:7JTX|rcsb pdb:7JUK|rcsb pdb:7JUL|rcsb pdb:7JVX|rcsb pdb:7PC7|rcsb pdb:8X3S|reactome:R-HSA-1660499|reactome:R-HSA-1855204|reactome:R-HSA-199418|reactome:R-HSA-202424|reactome:R-HSA-5628897|reactome:R-HSA-5674404|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-8943723|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8986944|refseq:NP_000305.3|refseq:NP_001291646.2|refseq:NP_001291647.1|efo:""Orphanet:101070""|efo:""Orphanet:109""|efo:""Orphanet:137608""|efo:""Orphanet:145""|efo:""Orphanet:201""|efo:""Orphanet:210548""|efo:""Orphanet:2969""|efo:""Orphanet:397596""|efo:""Orphanet:494547""|efo:""Orphanet:494550""|efo:""Orphanet:500464""|efo:""Orphanet:500478""|efo:""Orphanet:500481""|efo:""Orphanet:502363""|efo:""Orphanet:502366""|efo:""Orphanet:65285""|efo:""Orphanet:744""|efo:""Orphanet:79076""|dip:DIP-35019N|panther:PTHR12305(orthology-group)|ensembl:ENSP00000361021.3|ensembl:ENSP00000494918.2|ensembl:ENSP00000508752.1|ensembl:ENSP00000518242.1|ensembl:ENST00000710387.1|ensembl:ENSP00000518244.1"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:/cPQox/hRcR/ED//46U5w4lcsyc9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:9B42015303D99FD3|rigid:RBKuA8sR0PWdUMcTNbCfJI83AE8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P52434	uniprotkb:Q5NFP9	intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8|ensembl:ENSP00000392913.1	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298986|imex:IM-27563-641	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006223.2|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|ensembl:ENSG00000163882.10(gene)|ensembl:ENST00000456318.6(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005665""(RNA polymerase II, core complex)|go:""GO:0005666""(RNA polymerase III complex)|go:""GO:0005736""(RNA polymerase I complex)|go:""GO:0005829""(cytosol)|go:""GO:0006360""(transcription by RNA polymerase I)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006383""(transcription by RNA polymerase III)|go:""GO:0032993""(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7FJI|rcsb pdb:7FJJ|rcsb pdb:7LBM|rcsb pdb:7OB9|rcsb pdb:7OBA|rcsb pdb:7OBB|rcsb pdb:7VBA|rcsb pdb:7VBB|rcsb pdb:7VBC|rcsb pdb:8A43|rcsb pdb:8ITY|rcsb pdb:8IUE|rcsb pdb:8IUH|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N|panther:PTHR10917(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/27	rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:70C54EAC67CD6144|rigid:h9UxWqtLkUrQdNMMYO4G3zqhC+M	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99471	uniprotkb:Q5NFP9	intact:EBI-357275|ensembl:ENSP00000334188.4|ensembl:ENSP00000447942.1|ensembl:ENSP00000517421.1|ensembl:ENSP00000517429.1|intact:EBI-1047551|uniprotkb:A8K9A8|uniprotkb:Q54AA8|uniprotkb:Q9C083|uniprotkb:Q9C084	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:pfd5_human(display_long)|uniprotkb:c-Myc-binding protein Mm-1(gene name synonym)|uniprotkb:PFDN5(gene name)|psi-mi:PFDN5(display_short)|uniprotkb:MM1(gene name synonym)|uniprotkb:Myc modulator 1(gene name synonym)|uniprotkb:PFD5(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298926|imex:IM-27563-573	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000123349.15(gene)|ensembl:ENSG00000291834.1(gene)|ensembl:ENST00000334478.9(transcript)|ensembl:ENST00000551018.5(transcript)|ensembl:ENST00000708922.1(transcript)|ensembl:ENST00000708937.1(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006457""(protein folding)|go:""GO:0016272""(prefoldin complex)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1905907""(negative regulation of amyloid fibril formation)|go:""GO:1990113""(RNA polymerase I assembly)|go:""GO:1990114""(RNA polymerase II core complex assembly)|go:""GO:1990115""(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|mint:Q99471|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:7WU7|reactome:R-HSA-389957|panther:PTHR12674(orthology-group)|refseq:NP_002615.2|refseq:NP_665904.1|dip:DIP-28155N"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/26	rogid:Cm4km207qcfDJYRUCIwUxMBT4tE9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:E543F01DEB5AA470|rigid:Fh1oMy2dVbxS/fw3dC3/9t5J1Ws	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08174	uniprotkb:Q5NFP9	intact:EBI-1223952|uniprotkb:Q8IUP2|ensembl:ENSP00000378043.3	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:pcdh1_human(display_long)|uniprotkb:PCDH1(gene name)|psi-mi:PCDH1(display_short)|uniprotkb:Protocadherin-42(gene name synonym)|uniprotkb:Cadherin-like protein 1(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22298906|imex:IM-27563-405	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001265542.1|refseq:NP_001265544.1|refseq:NP_002578.2|refseq:NP_115796.2|ensembl:ENSG00000156453.14(gene)|ensembl:ENST00000394536.4(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007399""(nervous system development)|go:""GO:0030054""(cell junction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR013585(Protocadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR050174|mint:Q08174|rcsb pdb:6BX7|rcsb pdb:6MGA|rcsb pdb:6PIM|rcsb pdb:6VFP|panther:PTHR24028(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:Yqh1H2HOAVFNkWTdYY0mHWVL2Zo9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:0E34D8103AECF982|rigid:E7O3cWMK5RD1r4pBQVQItKEBR5o	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKA9	uniprotkb:Q5NEQ5	intact:EBI-954220|uniprotkb:Q8N0Z1|uniprotkb:Q8N160|uniprotkb:Q8NFB0|uniprotkb:Q8NFB1|uniprotkb:Q969N9|uniprotkb:Q96Q76|ensembl:ENSP00000502818.1	intact:EBI-2808269|uniprotkb:A0A0G2RQ71	psi-mi:ptbp2_human(display_long)|uniprotkb:Neurally-enriched homolog of PTB(gene name synonym)|uniprotkb:Neural polypyrimidine tract-binding protein(gene name synonym)|uniprotkb:PTB-like protein(gene name synonym)|uniprotkb:PTBP2(gene name)|psi-mi:PTBP2(display_short)|uniprotkb:NPTB(gene name synonym)|uniprotkb:PTB(gene name synonym)|uniprotkb:PTBLP(gene name synonym)	psi-mi:q5neq5_fratt(display_long)|uniprotkb:Polyphosphate kinase PPK2(gene name synonym)|uniprotkb:FTT_1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299064|imex:IM-27563-47	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067013.1|refseq:NP_001287914.1|refseq:NP_001287915.1|refseq:NP_001287916.1|refseq:NP_001287917.1|refseq:NP_001287918.1|refseq:NP_001287919.1|ensembl:ENSG00000117569.20(gene)|ensembl:ENST00000674951.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006376""(mRNA splice site recognition)|go:""GO:0033119""(negative regulation of RNA splicing)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:2000177""(regulation of neural precursor cell proliferation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034799|interpro:IPR034800|interpro:IPR035002|interpro:IPR035979|mint:Q9UKA9|rcsb pdb:2CQ1|rcsb pdb:2MJU|rcsb pdb:4CQ1|panther:PTHR15592(orthology-group)"	"interpro:IPR016898(Polyphosphate kinase 2, predicted)|interpro:IPR022488|interpro:IPR022486|refseq:YP_170487.1|refseq:WP_003014894.1|interpro:IPR027417|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0046872""(metal ion binding)|rcsb pdb:4YEG|rcsb pdb:5LL0|rcsb pdb:5LLB|rcsb pdb:5LLF|mint:Q5NEQ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:HRWj6xZbfhYShcsdMR97O7CD4/Y9606	rogid:3hIShFXVmkZdI9gV6zbu32j30jM177416	intact-crc:667D36FAA4EAA568|rigid:aouqcPY7/hiNbEbjOU8nyH1IhbE	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10644	uniprotkb:Q5NEC5	intact:EBI-476431|uniprotkb:Q567S7|ensembl:ENSP00000351410.1|ensembl:ENSP00000376475.1|ensembl:ENSP00000445625.1|ensembl:ENSP00000464715.2|ensembl:ENSP00000464977.2|ensembl:ENSP00000465013.2|ensembl:ENSP00000465445.2|ensembl:ENSP00000466459.1|ensembl:ENSP00000466649.2|uniprotkb:K7ER48	intact:EBI-22297545	psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299054|imex:IM-27563-315	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108946.17(gene)|ensembl:ENST00000358598.6(transcript)|ensembl:ENST00000392711.5(transcript)|ensembl:ENST00000536854.6(transcript)|ensembl:ENST00000585427.6(transcript)|ensembl:ENST00000586397.5(transcript)|ensembl:ENST00000588178.6(transcript)|ensembl:ENST00000589017.6(transcript)|ensembl:ENST00000589228.6(transcript)|ensembl:ENST00000589480.6(transcript)|go:""GO:0001707""(mesoderm formation)|go:""GO:0004862""(cAMP-dependent protein kinase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005771""(multivesicular body)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0008603""(cAMP-dependent protein kinase regulator activity)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030552""(cAMP binding)|go:""GO:0031588""(nucleotide-activated protein kinase complex)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045214""(sarcomere organization)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0071377""(cellular response to glucagon stimulus)|go:""GO:0097546""(ciliary base)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0120212""(sperm head-tail coupling apparatus)|go:""GO:0141162""(negative regulation of cAMP/PKA signal transduction)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR050503|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-983231|reactome:R-HSA-9856530|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|dip:DIP-34368N|efo:""Orphanet:1359""|efo:""Orphanet:1501""|efo:""Orphanet:520""|efo:""Orphanet:615""|efo:""Orphanet:950""|panther:PTHR11635(orthology-group)|ensembl:ENSP00000351410.1|ensembl:ENSP00000376475.1|ensembl:ENSP00000445625.1|ensembl:ENSP00000464715.2|ensembl:ENST00000585981.6|ensembl:ENSP00000467311.2|ensembl:ENSP00000466459.1|ensembl:ENSP00000465013.2|ensembl:ENST00000588188.7|ensembl:ENSP00000468106.2|ensembl:ENSP00000465445.2|ensembl:ENSP00000464977.2|ensembl:ENSP00000466649.2|ensembl:ENST00000711037.1|ensembl:ENSP00000518555.1"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/01	rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:FAD901B77E4808C5|rigid:9rPNNxLdrg7bR7JDIvUI2Eukiks	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z4L9	uniprotkb:Q5NHT8	intact:EBI-20861779|uniprotkb:G3V118|ensembl:ENSP00000429721.1	intact:EBI-2806309	psi-mi:ppr42_human(display_long)|uniprotkb:Leucine-rich repeat-containing protein 67(gene name synonym)|uniprotkb:PPP1R42(gene name)|psi-mi:PPP1R42(display_short)|uniprotkb:LRRC67(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299024|imex:IM-27563-45	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001013648.1|refseq:NP_001335492.1|panther:PTHR45973(orthology-group)|ensembl:ENSG00000178125.15(gene)|ensembl:ENST00000522909.5(transcript)|go:""GO:0002177""(manchette)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015631""(tubulin binding)|go:""GO:0070840""(dynein complex binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|interpro:IPR050836|mint:Q7Z4L9"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:Yz6kBX8B96wPZIccbK+NXyae12g9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:FE516CA56CC1A95B|rigid:knzZq0zyqFh4GlM/U5CoKTAy0/M	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IXI2	uniprotkb:Q5NEM9	intact:EBI-1396430|uniprotkb:A4FVB6|uniprotkb:Q6NUR3|uniprotkb:Q6P9F8|uniprotkb:Q6PJG1|uniprotkb:Q6YMW8|uniprotkb:Q86UB0|uniprotkb:Q8IW28|uniprotkb:Q8IXJ7|uniprotkb:Q9H067|uniprotkb:Q9H9N8|uniprotkb:Q9NUZ2|uniprotkb:A6NFV0|uniprotkb:B4DG48|uniprotkb:J9JIH9|ensembl:ENSP00000334724.6	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:miro1_human(display_long)|uniprotkb:Ras homolog gene family member T1(gene name synonym)|uniprotkb:Rac-GTP-binding protein-like protein(gene name synonym)|uniprotkb:RHOT1(gene name)|psi-mi:RHOT1(display_short)|uniprotkb:ARHT1(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299134|imex:IM-27563-645	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001028738.1|refseq:NP_001028740.1|refseq:NP_060777.3|refseq:NP_001028739.2|refseq:NP_001275683.1|refseq:NP_001275684.1|refseq:NP_001275687.1|ensembl:ENSG00000126858.19(gene)|ensembl:ENST00000333942.10(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0016020""(membrane)|go:""GO:0019725""(cellular homeostasis)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0097345""(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|interpro:IPR052266|mint:Q8IXI2|rcsb pdb:5KSO|rcsb pdb:5KSP|rcsb pdb:5KSY|rcsb pdb:5KSZ|rcsb pdb:5KTY|rcsb pdb:5KU1|rcsb pdb:6D71|reactome:R-HSA-5689880|reactome:R-HSA-9013425|dip:DIP-39114N|panther:PTHR24072(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/01	rogid:gA6A8bgSwshvMwCO0cG66h+wwIY9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:1711F17FFAA8251D|rigid:ZcjhCOnVD12bk4gxxVS63HVTfAY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10826	uniprotkb:Q5NFP9	intact:EBI-2568838|uniprotkb:P12891|uniprotkb:Q00989|uniprotkb:Q15298|uniprotkb:Q9UN48|ensembl:ENSP00000373282.5|ensembl:ENSP00000508588.1|ensembl:ENSP00000510313.1|ensembl:ENSP00000510539.1|ensembl:ENSP00000510650.1	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:rarb_human(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299114|imex:IM-27563-575	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000077092.20(gene)|ensembl:ENST00000383772.9(transcript)|ensembl:ENST00000686715.1(transcript)|ensembl:ENST00000687353.1(transcript)|ensembl:ENST00000687676.1(transcript)|ensembl:ENST00000688892.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001657""(ureteric bud development)|go:""GO:0002068""(glandular epithelial cell development)|go:""GO:0003148""(outflow tract septum morphogenesis)|go:""GO:0003417""(growth plate cartilage development)|go:""GO:0003677""(DNA binding)|go:""GO:0004879""(nuclear receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0008270""(zinc ion binding)|go:""GO:0021756""(striatum development)|go:""GO:0022008""(neurogenesis)|go:""GO:0030154""(cell differentiation)|go:""GO:0031641""(regulation of myelination)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0048566""(embryonic digestive tract development)|go:""GO:0055012""(ventricular cardiac muscle cell differentiation)|go:""GO:0061351""(neural precursor cell proliferation)|go:""GO:0072089""(stem cell proliferation)|go:""GO:1901363""(heterocyclic compound binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000647""(negative regulation of stem cell proliferation)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR047158|interpro:IPR047159|mint:P10826|rcsb pdb:1HRA|rcsb pdb:1XAP|rcsb pdb:4DM6|rcsb pdb:4DM8|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:5UAN|rcsb pdb:6SSQ|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-5617472|refseq:NP_000956.2|refseq:NP_001277145.1|refseq:NP_001277146.1|refseq:NP_001277195.1|refseq:NP_001277205.1|refseq:NP_057236.1|efo:""Orphanet:2470""|panther:PTHR24082(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:GviMMhEdTqNBuvQ8p2XTKxllgdc9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:E2AFBF20A250D005|rigid:al7qeYRn0b/TD7yKCHsAtQC8noE	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49792	uniprotkb:Q5NHH2	intact:EBI-973138|ensembl:ENSP00000283195.6|intact:EBI-28970106|uniprotkb:Q13074|uniprotkb:Q15280|uniprotkb:Q53TE2|uniprotkb:Q59FH7	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:rbp2_human(display_long)|uniprotkb:RANBP2(gene name)|psi-mi:RANBP2(display_short)|uniprotkb:NUP358(gene name synonym)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup358(gene name synonym)|uniprotkb:Nucleoporin Nup358(gene name synonym)|uniprotkb:358 kDa nucleoporin(gene name synonym)|uniprotkb:p270(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299104|imex:IM-27563-155	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000153201.17(gene)|ensembl:ENST00000283195.11(transcript)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005642""(annulate lamellae)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006111""(regulation of gluconeogenesis)|go:""GO:0006457""(protein folding)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0016020""(membrane)|go:""GO:0016925""(protein sumoylation)|go:""GO:0019789""(SUMO transferase activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042405""(nuclear inclusion body)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044614""(nuclear pore cytoplasmic filaments)|go:""GO:0044615""(nuclear pore nuclear basket)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051028""(mRNA transport)|go:""GO:0051168""(nuclear export)|go:""GO:0051642""(centrosome localization)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0106068""(SUMO ligase complex)|go:""GO:1990723""(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|interpro:IPR045255|mint:P49792|rcsb pdb:1RRP|rcsb pdb:1XKE|rcsb pdb:1Z5S|rcsb pdb:2LAS|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4GA0|rcsb pdb:4I9Y|rcsb pdb:4L6E|rcsb pdb:4LQW|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:7MNJ|rcsb pdb:7MNK|rcsb pdb:7MNL|rcsb pdb:7MNM|rcsb pdb:7MNN|rcsb pdb:7MNO|rcsb pdb:7MNP|rcsb pdb:7MNQ|rcsb pdb:7MNR|rcsb pdb:7MNS|rcsb pdb:7MNT|rcsb pdb:7MNU|rcsb pdb:7MNV|rcsb pdb:7MNW|rcsb pdb:7MNX|rcsb pdb:7MNY|rcsb pdb:7MNZ|rcsb pdb:7R5J|rcsb pdb:7R5K|rcsb pdb:9B62|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9648025|reactome:R-HSA-9705671|reactome:R-HSA-9725370|refseq:NP_006258.3|efo:""Orphanet:178342""|efo:""Orphanet:263524""|efo:""Orphanet:88619""|dip:DIP-37654N|panther:PTHR23138(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/10	rogid:KB+rjfw8djVygvDpTncA0NO2MDY9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:D9EB55CFA3BF78B3|rigid:+SMiI2z3o9hwS9Q/44kfMAb3MaU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99496	uniprotkb:Q5NGJ5	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480.3|ensembl:ENSP00000520426.1	intact:EBI-22297738|uniprotkb:A0A0G2RPF6	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:q5ngj5_fratt(display_long)|uniprotkb:FTT_0842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299154|imex:IM-27563-647	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000121481.12(gene)|ensembl:ENST00000367510.8(transcript)|ensembl:ENST00000715230.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000791""(euchromatin)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001739""(sex chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0007281""(germ cell development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0010467""(gene expression)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0071339""(MLL1 complex)|go:""GO:0071535""(RING-like zinc finger domain binding)|go:""GO:0140862""(histone H2AK119 ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|rcsb pdb:8GRM|rcsb pdb:8PP7|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|panther:PTHR46076(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|interpro:IPR050330|refseq:WP_003020808.1|refseq:YP_169847.1|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|mint:Q5NGJ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/27	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:/Dq7r5H2A4RbaDlrrHYQHMOGtbc177416	intact-crc:8DD1EE4BA24362D2|rigid:EKZGg17u0tzWYSTzv4gWwWp7+nY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99496	uniprotkb:Q5NGE3	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480.3|ensembl:ENSP00000520426.1	intact:EBI-22297821|uniprotkb:A0A0G2RPC6	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:q5nge3_fratt(display_long)|uniprotkb:FTT_0902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299164|imex:IM-27563-497	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000121481.12(gene)|ensembl:ENST00000367510.8(transcript)|ensembl:ENST00000715230.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000791""(euchromatin)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001739""(sex chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0007281""(germ cell development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0010467""(gene expression)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0071339""(MLL1 complex)|go:""GO:0071535""(RING-like zinc finger domain binding)|go:""GO:0140862""(histone H2AK119 ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|rcsb pdb:8GRM|rcsb pdb:8PP7|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|panther:PTHR46076(orthology-group)"	refseq:YP_169899.1|mint:Q5NGE3	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/27	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:NCB/Hok6C9lpbhvu2mMcLmSbgZs177416	intact-crc:36DD0ADC3D257799|rigid:lpA2pRU3n0jlD6JWtRzB76jdGjU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96PU8	uniprotkb:Q5NHH2	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094.3	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)|uniprotkb:Protein quaking(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299094|imex:IM-27563-409	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000112531.17(gene)|ensembl:ENST00000361752.8(transcript)|go:""GO:0001570""(vasculogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007286""(spermatid development)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010717""(regulation of epithelial to mesenchymal transition)|go:""GO:0014004""(microglia differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031643""(positive regulation of myelination)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0035198""(miRNA binding)|go:""GO:0035886""(vascular associated smooth muscle cell differentiation)|go:""GO:0042552""(myelination)|go:""GO:0042759""(long-chain fatty acid biosynthetic process)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045649""(regulation of macrophage differentiation)|go:""GO:0045650""(negative regulation of macrophage differentiation)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0048710""(regulation of astrocyte differentiation)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0051028""(mRNA transport)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0160089""(""internal N(7)-methylguanine-containing RNA reader activity"")|go:""GO:0160091""(spliceosome-depend formation of circular RNA)|go:""GO:1905869""(negative regulation of 3'-UTR-mediated mRNA stabilization)|go:""GO:1990764""(myofibroblast contraction)|go:""GO:2000626""(negative regulation of miRNA catabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|interpro:IPR045071|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952|refseq:NP_001288014.1|refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:XP_011534561.1|efo:""Orphanet:251671""|ensembl:ENST00000275262.11|ensembl:ENSP00000275262.7|ensembl:ENST00000361195.6|ensembl:ENSP00000354867.2|ensembl:ENSP00000355094.3|ensembl:ENST00000361758.8|ensembl:ENSP00000354951.4|ensembl:ENST00000392127.6|ensembl:ENSP00000375973.2|ensembl:ENST00000424802.7|ensembl:ENSP00000408382.3|ensembl:ENST00000453779.6|ensembl:ENSP00000408775.2|panther:PTHR11208(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:37FB9438AA905631|rigid:kke0262Xx+T8LgRw74unGe7dYbQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y580	uniprotkb:Q5NEQ5	intact:EBI-746903|ensembl:ENSP00000439918.1|uniprotkb:Q9NUT4|uniprotkb:B2R6K8	intact:EBI-2808269|uniprotkb:A0A0G2RQ71	psi-mi:rbm7_human(display_long)|uniprotkb:RNA-binding motif protein 7(gene name synonym)|uniprotkb:RBM7(gene name)|psi-mi:RBM7(display_short)	psi-mi:q5neq5_fratt(display_long)|uniprotkb:Polyphosphate kinase PPK2(gene name synonym)|uniprotkb:FTT_1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299124|imex:IM-27563-49	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001272974.1|refseq:NP_001272975.1|refseq:NP_001272976.1|refseq:NP_001272977.1|ensembl:ENSG00000076053.12(gene)|ensembl:ENST00000540163.5(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016076""(snRNA catabolic process)|go:""GO:0017069""(snRNA binding)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0097157""(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034500|interpro:IPR035979|interpro:IPR052285|mint:Q9Y580|rcsb pdb:2M8H|rcsb pdb:5IQQ|rcsb pdb:5LXR|rcsb pdb:5LXY|rcsb pdb:7S7B|rcsb pdb:7S7C|reactome:R-HSA-72163|reactome:R-HSA-9843970|refseq:NP_057174.1|dip:DIP-48833N|panther:PTHR13798(orthology-group)"	"interpro:IPR016898(Polyphosphate kinase 2, predicted)|interpro:IPR022488|interpro:IPR022486|refseq:YP_170487.1|refseq:WP_003014894.1|interpro:IPR027417|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0046872""(metal ion binding)|rcsb pdb:4YEG|rcsb pdb:5LL0|rcsb pdb:5LLB|rcsb pdb:5LLF|mint:Q5NEQ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/23	rogid:d39RjBQTHAVQlOsmrxMX0NCR8CU9606	rogid:3hIShFXVmkZdI9gV6zbu32j30jM177416	intact-crc:C9D73B104EDAF945|rigid:067oOpJkA7JPd8hiGzjPk+qd1+0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99496	uniprotkb:Q5NHT8	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480.3|ensembl:ENSP00000520426.1	intact:EBI-2806309	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299144|imex:IM-27563-317	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000121481.12(gene)|ensembl:ENST00000367510.8(transcript)|ensembl:ENST00000715230.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000791""(euchromatin)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001739""(sex chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0007281""(germ cell development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0010467""(gene expression)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0071339""(MLL1 complex)|go:""GO:0071535""(RING-like zinc finger domain binding)|go:""GO:0140862""(histone H2AK119 ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|rcsb pdb:8GRM|rcsb pdb:8PP7|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|panther:PTHR46076(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/27	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:D3C82ADFC985D0DB|rigid:iNk6A3TYAbPdCJ6nJjnX1wteRGk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P29350	uniprotkb:Q5NEM9	intact:EBI-78260|intact:EBI-28977917|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67|ensembl:ENSP00000326010.9	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299084|imex:IM-27563-247	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR46257(orthology-group)|dip:DIP-31002N|interpro:IPR036860|efo:""Orphanet:3243""|efo:""Orphanet:538863""|efo:""Orphanet:538866""|efo:""Orphanet:538869""|efo:""Orphanet:538872""|ensembl:ENSG00000111679.17(gene)|ensembl:ENST00000318974.14(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002924""(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033007""(negative regulation of mast cell activation involved in immune response)|go:""GO:0033630""(positive regulation of cell adhesion mediated by integrin)|go:""GO:0035335""(peptidyl-tyrosine dephosphorylation)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042105""(alpha-beta T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050732""(negative regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1905867""(epididymis development)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR052123|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:3PS5|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|rcsb pdb:8YHI|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-201556|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9705671|reactome:R-HSA-9725371|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|refseq:XP_011519290.1"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:2B478B0E6DA1CA24|rigid:ITRFSaKKP2agg+JmqHCaXUAK9CI	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15047	uniprotkb:Q5NEQ5	intact:EBI-79691|uniprotkb:A6NEW2|uniprotkb:Q5SZD8|uniprotkb:Q5SZD9|uniprotkb:Q5SZE0|uniprotkb:Q5SZE7|uniprotkb:Q96GM9|ensembl:ENSP00000271640.5	intact:EBI-2808269|uniprotkb:A0A0G2RQ71	psi-mi:setb1_human(display_long)|uniprotkb:SETDB1(gene name)|psi-mi:SETDB1(display_short)|uniprotkb:KIAA0067(gene name synonym)|uniprotkb:KMT1E(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ERG-associated protein with SET domain(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1E(gene name synonym)|uniprotkb:ESET(gene name synonym)	psi-mi:q5neq5_fratt(display_long)|uniprotkb:Polyphosphate kinase PPK2(gene name synonym)|uniprotkb:FTT_1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299291|imex:IM-27563-321	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138887.1|refseq:NP_001230420.1|refseq:NP_036564.3|refseq:XP_016858444.1|panther:PTHR46024(orthology-group)|dip:DIP-31029N|ensembl:ENSP00000271640.5|ensembl:ENST00000368962.6|ensembl:ENSP00000357958.2|ensembl:ENST00000368969.8|ensembl:ENSP00000357965.4|ensembl:ENSG00000143379.13(gene)|ensembl:ENST00000271640.9(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006346""(DNA methylation-dependent constitutive heterochromatin formation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0032259""(methylation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046974""(histone H3K9 methyltransferase activity)|go:""GO:0070828""(heterochromatin organization)|go:""GO:0140938""(histone H3 methyltransferase activity)|go:""GO:0140947""(histone H3K9me2 methyltransferase activity)|go:""GO:0140948""(histone H3K9 monomethyltransferase activity)|go:""GO:0140949""(histone H3K9 trimethyltransferase activity)|go:""GO:0141005""(transposable element silencing by heterochromatin formation)|go:""GO:1990841""(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025796|interpro:IPR040880|interpro:IPR041291|interpro:IPR041292|interpro:IPR046341|interpro:IPR047232|interpro:IPR051516|mint:Q15047|rcsb pdb:3DLM|rcsb pdb:4X3S|rcsb pdb:5KCH|rcsb pdb:5KCO|rcsb pdb:5KE2|rcsb pdb:5KE3|rcsb pdb:5KH6|rcsb pdb:5QT1|rcsb pdb:5QT2|rcsb pdb:6AU2|rcsb pdb:6AU3|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6BPI|rcsb pdb:7C9N|rcsb pdb:7CAJ|rcsb pdb:7CD9|rcsb pdb:7CJT|rcsb pdb:8G5E|rcsb pdb:8IYA|rcsb pdb:8UWP|rcsb pdb:9CUW|rcsb pdb:9CUX|reactome:R-HSA-3214841|reactome:R-HSA-9843940|reactome:R-HSA-9843970"	"interpro:IPR016898(Polyphosphate kinase 2, predicted)|interpro:IPR022488|interpro:IPR022486|refseq:YP_170487.1|refseq:WP_003014894.1|interpro:IPR027417|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0046872""(metal ion binding)|rcsb pdb:4YEG|rcsb pdb:5LL0|rcsb pdb:5LLB|rcsb pdb:5LLF|mint:Q5NEQ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/01	rogid:ydyGndAZ5b35jF07y4WFUeHFFvE9606	rogid:3hIShFXVmkZdI9gV6zbu32j30jM177416	intact-crc:15DF06AC4301E4F2|rigid:crjumY8/IfyGUignn0trrXnkiH8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H0F5	uniprotkb:Q5NFP9	intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748|ensembl:ENSP00000259605.6	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299211|imex:IM-27563-413	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1|ensembl:ENSG00000137075.18(gene)|ensembl:ENST00000259605.11(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008584""(male gonad development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0036126""(sperm flagellum)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:7OJX|panther:PTHR46171(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:A9AFD8853B690305|rigid:LrrQ8cdXKYhmbwXaUDU6nVZ7i5c	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H0F5	uniprotkb:Q5NEC5	intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748|ensembl:ENSP00000259605.6	intact:EBI-22297545	psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299221|imex:IM-27563-249	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1|ensembl:ENSG00000137075.18(gene)|ensembl:ENST00000259605.11(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008584""(male gonad development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0036126""(sperm flagellum)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:7OJX|panther:PTHR46171(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:3DD8958122496A54|rigid:C93NKeKN/V6RLJWgYAA3jCcanZ8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95104	uniprotkb:Q5NES6	intact:EBI-2854897|uniprotkb:Q6P1M5|uniprotkb:Q8N3I8|uniprotkb:Q9ULP8|uniprotkb:Q0P5W8|uniprotkb:Q9UFM1|uniprotkb:C9JLZ0|ensembl:ENSP00000286835.7	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:scaf4_human(display_long)|uniprotkb:SCAF4(gene name)|psi-mi:SCAF4(display_short)|uniprotkb:Splicing factor, arginine/serine-rich 15(gene name synonym)|uniprotkb:SFRS15(gene name synonym)|uniprotkb:KIAA1172(gene name synonym)|uniprotkb:CTD-binding SR-like protein RA4(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299261|imex:IM-27563-577	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034369|interpro:IPR035979|interpro:IPR051485|mint:O95104|rcsb pdb:6XKB|refseq:NP_001138916.1|refseq:NP_001138917.1|ensembl:ENSG00000156304.15(gene)|ensembl:ENST00000286835.12(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:1990269""(RNA polymerase II C-terminal domain phosphoserine binding)|go:""GO:2000805""(""negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled"")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|refseq:NP_065757.1|panther:PTHR23140(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:l++VfjjY/kfVHl+bhXTWsyyL4Zc9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:6778E21098F95526|rigid:acmsHTxKjqA0ipBeH7UVkt4snEM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16585	uniprotkb:Q5NEC5	intact:EBI-5663627|uniprotkb:O00661|uniprotkb:B7Z635|ensembl:ENSP00000370839.6	intact:EBI-22297545	psi-mi:sgcb_human(display_long)|uniprotkb:43 kDa dystrophin-associated glycoprotein(gene name synonym)|uniprotkb:A3b(gene name synonym)|uniprotkb:SGCB(gene name)|psi-mi:SGCB(display_short)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299301|imex:IM-27563-415	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:119""|ensembl:ENSG00000163069.13(gene)|ensembl:ENST00000381431.10(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0007517""(muscle organ development)|go:""GO:0009749""(response to glucose)|go:""GO:0010467""(gene expression)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016012""(sarcoglycan complex)|go:""GO:0042383""(sarcolemma)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0044381""(glucose import in response to insulin stimulus)|go:""GO:0055013""(cardiac muscle cell development)|go:""GO:0097084""(vascular associated smooth muscle cell development)|interpro:IPR006875(Sarcoglycan complex subunit protein)|interpro:IPR027659|mint:Q16585|refseq:NP_000223.1|panther:PTHR21142(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:3kGYgS5HdH4e/aCHMtAnVJQDYjI9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:ABC264DA835B94E2|rigid:UtggccGi7I9p+txM+hojt9MuB58	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15047	uniprotkb:Q5NHT8	intact:EBI-79691|uniprotkb:A6NEW2|uniprotkb:Q5SZD8|uniprotkb:Q5SZD9|uniprotkb:Q5SZE0|uniprotkb:Q5SZE7|uniprotkb:Q96GM9|ensembl:ENSP00000271640.5	intact:EBI-2806309	psi-mi:setb1_human(display_long)|uniprotkb:SETDB1(gene name)|psi-mi:SETDB1(display_short)|uniprotkb:KIAA0067(gene name synonym)|uniprotkb:KMT1E(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ERG-associated protein with SET domain(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1E(gene name synonym)|uniprotkb:ESET(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299281|imex:IM-27563-161	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138887.1|refseq:NP_001230420.1|refseq:NP_036564.3|refseq:XP_016858444.1|panther:PTHR46024(orthology-group)|dip:DIP-31029N|ensembl:ENSP00000271640.5|ensembl:ENST00000368962.6|ensembl:ENSP00000357958.2|ensembl:ENST00000368969.8|ensembl:ENSP00000357965.4|ensembl:ENSG00000143379.13(gene)|ensembl:ENST00000271640.9(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006346""(DNA methylation-dependent constitutive heterochromatin formation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0032259""(methylation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046974""(histone H3K9 methyltransferase activity)|go:""GO:0070828""(heterochromatin organization)|go:""GO:0140938""(histone H3 methyltransferase activity)|go:""GO:0140947""(histone H3K9me2 methyltransferase activity)|go:""GO:0140948""(histone H3K9 monomethyltransferase activity)|go:""GO:0140949""(histone H3K9 trimethyltransferase activity)|go:""GO:0141005""(transposable element silencing by heterochromatin formation)|go:""GO:1990841""(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002999(Tudor)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025796|interpro:IPR040880|interpro:IPR041291|interpro:IPR041292|interpro:IPR046341|interpro:IPR047232|interpro:IPR051516|mint:Q15047|rcsb pdb:3DLM|rcsb pdb:4X3S|rcsb pdb:5KCH|rcsb pdb:5KCO|rcsb pdb:5KE2|rcsb pdb:5KE3|rcsb pdb:5KH6|rcsb pdb:5QT1|rcsb pdb:5QT2|rcsb pdb:6AU2|rcsb pdb:6AU3|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6BPI|rcsb pdb:7C9N|rcsb pdb:7CAJ|rcsb pdb:7CD9|rcsb pdb:7CJT|rcsb pdb:8G5E|rcsb pdb:8IYA|rcsb pdb:8UWP|rcsb pdb:9CUW|rcsb pdb:9CUX|reactome:R-HSA-3214841|reactome:R-HSA-9843940|reactome:R-HSA-9843970"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/01	rogid:ydyGndAZ5b35jF07y4WFUeHFFvE9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:A6FAC8CCF2DEC88A|rigid:VTZl5NmdlYKaoAmgRcaXVsU3NQU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q93073	uniprotkb:Q5NEC5	intact:EBI-2805647|uniprotkb:Q8N767|ensembl:ENSP00000453854.1	intact:EBI-22297545	psi-mi:sbp2l_human(display_long)|uniprotkb:KIAA0256(gene name synonym)|uniprotkb:SECISBP2L(gene name)|psi-mi:SECISBP2L(display_short)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299271|imex:IM-27563-159	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001180418.1|refseq:NP_055516.2|ensembl:ENSG00000138593.9(gene)|ensembl:ENST00000559471.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0035368""(selenocysteine insertion sequence binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|interpro:IPR040051|mint:Q93073|panther:PTHR13284(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:h2ByJoTHpYKWrIRaWpnqy4LbkUk9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:DC2465C136B0FF36|rigid:u6fjY6yXegwIJlkm17PpxknW0CQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z6J0	uniprotkb:Q5NFP9	intact:EBI-311339|intact:EBI-1374106|uniprotkb:Q05BT2|uniprotkb:Q8IW46|uniprotkb:Q9HAM2|uniprotkb:Q9P234|ensembl:ENSP00000284637.9	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:sh3r1_human(display_long)|uniprotkb:SH3RF1(gene name)|psi-mi:SH3RF1(display_short)|uniprotkb:POSH1(gene name synonym)|uniprotkb:KIAA1494(gene name synonym)|uniprotkb:POSH(gene name synonym)|uniprotkb:RNF142(gene name synonym)|uniprotkb:SH3MD2(gene name synonym)|uniprotkb:SH3 domain-containing RING finger protein 1(gene name synonym)|uniprotkb:Plenty of SH3s(gene name synonym)|uniprotkb:SH3 multiple domains protein 2(gene name synonym)|uniprotkb:RING finger protein 142(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SH3RF1(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299321|imex:IM-27563-419	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_065921.2|ensembl:ENSG00000154447.15(gene)|ensembl:ENST00000284637.14(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030027""(lamellipodium)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043370""(regulation of CD4-positive, alpha-beta T cell differentiation)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:1904044""(response to aldosterone)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000564""(regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR035795|interpro:IPR035816|interpro:IPR036028|interpro:IPR050384|mint:Q7Z6J0|rcsb pdb:7NZC|rcsb pdb:7NZD|reactome:R-HSA-9013424|reactome:R-HSA-983168|dip:DIP-31636N|panther:PTHR14167(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:xt8KC10AwFS6xTZVVApagbbyiJ49606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:A8C9F22AEE4BFF43|rigid:QNUFVLJRzwVQIs/F2OZd4OkVrU0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75116	uniprotkb:Q5NHT8	intact:EBI-366288|uniprotkb:Q9UQN5|uniprotkb:Q53QZ0|uniprotkb:Q53SJ7|ensembl:ENSP00000317985.6	intact:EBI-2806309	psi-mi:rock2_human(display_long)|uniprotkb:ROCK2(gene name)|psi-mi:ROCK2(display_short)|uniprotkb:KIAA0619(gene name synonym)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase II(gene name synonym)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 2(gene name synonym)|uniprotkb:p164 ROCK-2(gene name synonym)|uniprotkb:Rho kinase 2(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299231|imex:IM-27563-157	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004841.2|refseq:NP_001308572.1|ensembl:ENSG00000134318.16(gene)|ensembl:ENST00000315872.11(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0002931""(response to ischemia)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006939""(smooth muscle contraction)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010613""(positive regulation of cardiac muscle hypertrophy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010825""(positive regulation of centrosome duplication)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031644""(regulation of nervous system process)|go:""GO:0032723""(positive regulation of connective tissue growth factor production)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045019""(negative regulation of nitric oxide biosynthetic process)|go:""GO:0045616""(regulation of keratinocyte differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0048156""(tau protein binding)|go:""GO:0048511""(rhythmic process)|go:""GO:0048598""(embryonic morphogenesis)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0051298""(centrosome duplication)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0061133""(endopeptidase activator activity)|go:""GO:0061157""(mRNA destabilization)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0071394""(cellular response to testosterone stimulus)|go:""GO:0071559""(response to transforming growth factor beta)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090271""(positive regulation of fibroblast growth factor production)|go:""GO:0097746""(blood vessel diameter maintenance)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0110061""(regulation of angiotensin-activated signaling pathway)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:0150033""(negative regulation of protein localization to lysosome)|go:""GO:1900037""(regulation of cellular response to hypoxia)|go:""GO:1901888""(regulation of cell junction assembly)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902966""(positive regulation of protein localization to early endosome)|go:""GO:1902993""(positive regulation of amyloid precursor protein catabolic process)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903347""(negative regulation of bicellular tight junction assembly)|go:""GO:1905145""(cellular response to acetylcholine)|go:""GO:1905205""(positive regulation of connective tissue replacement)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990776""(response to angiotensin)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR029878|interpro:IPR037311|interpro:IPR046349|interpro:IPR050839|mint:O75116|rcsb pdb:4L6Q|rcsb pdb:4WOT|rcsb pdb:5U7Q|rcsb pdb:5U7R|rcsb pdb:6ED6|rcsb pdb:6P5M|rcsb pdb:6P5P|rcsb pdb:7JNT|rcsb pdb:7JOV|rcsb pdb:7P6N|rcsb pdb:8GDS|rcsb pdb:9EP8|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5627117|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013407|reactome:R-HSA-9013422|reactome:R-HSA-9679191|panther:PTHR22988(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:iCgqC5U/DXAzOEq6edMtL6ncK7U9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:7C35254ED7A3E810|rigid:nt1XB7Ld0yJ7nEqxGGo/MpYWazU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16348	uniprotkb:Q5NHT8	intact:EBI-12806032|uniprotkb:A8K1A5|uniprotkb:B4E2A7|ensembl:ENSP00000417085.1	intact:EBI-2806309	"psi-mi:s15a2_human(display_long)|uniprotkb:SLC15A2(gene name)|psi-mi:SLC15A2(display_short)|uniprotkb:""Kidney H(+)/peptide cotransporter""(gene name synonym)|uniprotkb:Oligopeptide transporter, kidney isoform(gene name synonym)|uniprotkb:PEPT2(gene name synonym)|uniprotkb:Peptide transporter 2(gene name synonym)"	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299341|imex:IM-27563-421	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11654(orthology-group)|refseq:NP_001139470.1|refseq:NP_066568.3|ensembl:ENSG00000163406.11(gene)|ensembl:ENST00000489711.6(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0015031""(protein transport)|go:""GO:0015333""(""peptide:proton symporter activity"")|go:""GO:0015835""(peptidoglycan transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0042908""(xenobiotic transport)|go:""GO:0042937""(tripeptide transmembrane transporter activity)|go:""GO:0042938""(dipeptide transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070293""(renal absorption)|go:""GO:0070424""(regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:""GO:0071916""(dipeptide transmembrane transporter activity)|go:""GO:0140206""(dipeptide import across plasma membrane)|go:""GO:0140207""(tripeptide import across plasma membrane)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR004768(""Oligopeptide transporter, peptide:H+ symporter"")|interpro:IPR018456|interpro:IPR029028|interpro:IPR036259|mint:Q16348|rcsb pdb:6EZI|rcsb pdb:7PMY"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:GvnWmFvYdawnD48dAh7S4aYkayc9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:FA538A4DD508CD0A|rigid:LcIM11GyzOV0j70B62+iZ8pnCHI	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16348	uniprotkb:Q5NEV0	intact:EBI-12806032|uniprotkb:A8K1A5|uniprotkb:B4E2A7|ensembl:ENSP00000417085.1	intact:EBI-22299174|uniprotkb:A0A0G2RP53	"psi-mi:s15a2_human(display_long)|uniprotkb:SLC15A2(gene name)|psi-mi:SLC15A2(display_short)|uniprotkb:""Kidney H(+)/peptide cotransporter""(gene name synonym)|uniprotkb:Oligopeptide transporter, kidney isoform(gene name synonym)|uniprotkb:PEPT2(gene name synonym)|uniprotkb:Peptide transporter 2(gene name synonym)"	"psi-mi:q5nev0_fratt(display_long)|uniprotkb:relA(gene name)|psi-mi:relA(display_short)|uniprotkb:""(p)ppGpp synthase""(gene name synonym)|uniprotkb:""ATP:GTP 3'-pyrophosphotransferase""(gene name synonym)|uniprotkb:ppGpp synthase I(gene name synonym)|uniprotkb:FTT_1508c(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299351|imex:IM-27563-499	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11654(orthology-group)|refseq:NP_001139470.1|refseq:NP_066568.3|ensembl:ENSG00000163406.11(gene)|ensembl:ENST00000489711.6(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0015031""(protein transport)|go:""GO:0015333""(""peptide:proton symporter activity"")|go:""GO:0015835""(peptidoglycan transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0042908""(xenobiotic transport)|go:""GO:0042937""(tripeptide transmembrane transporter activity)|go:""GO:0042938""(dipeptide transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070293""(renal absorption)|go:""GO:0070424""(regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:""GO:0071916""(dipeptide transmembrane transporter activity)|go:""GO:0140206""(dipeptide import across plasma membrane)|go:""GO:0140207""(tripeptide import across plasma membrane)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR004768(""Oligopeptide transporter, peptide:H+ symporter"")|interpro:IPR018456|interpro:IPR029028|interpro:IPR036259|mint:Q16348|rcsb pdb:6EZI|rcsb pdb:7PMY"	"go:""GO:0005525""(GTP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0008728""(GTP diphosphokinase activity)|go:""GO:0008893""(""guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"")|go:""GO:0015969""(guanosine tetraphosphate metabolic process)|go:""GO:0016301""(kinase activity)|go:""GO:0042594""(response to starvation)|refseq:WP_003025932.1|refseq:YP_170442.1|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004811(RelA/SpoT protein)|interpro:IPR007685(RelA/SpoT)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|interpro:IPR033655|mint:Q5NEV0|interpro:IPR043519"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:GvnWmFvYdawnD48dAh7S4aYkayc9606	rogid:j8MreXRGyjWTWSOsZagqQx0cTxU177416	intact-crc:74AE0090BF83F450|rigid:MaGXR/bl0bPL63FybmKstnWZV7M	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BQI5	uniprotkb:Q5NES6	intact:EBI-2690801|uniprotkb:Q6MZY6|uniprotkb:A6NLD1|uniprotkb:Q5VYE2|uniprotkb:A6NL81|uniprotkb:Q8IWC2|uniprotkb:Q68D76|uniprotkb:Q4LE32|uniprotkb:Q5VYE4|uniprotkb:Q5VYE3|ensembl:ENSP00000360076.3	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:sgip1_human(display_long)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)|uniprotkb:SGIP1(gene name)|psi-mi:SGIP1(display_short)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299311|imex:IM-27563-417	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001295132.1|refseq:XP_016858000.1|refseq:XP_016858001.1|refseq:XP_016858023.1|refseq:XP_016858024.1|refseq:NP_115667.2|refseq:XP_005271321.1|refseq:XP_005271327.1|refseq:XP_006711037.1|ensembl:ENSG00000118473.23(gene)|ensembl:ENST00000371037.9(transcript)|go:""GO:0002021""(response to dietary excess)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0008017""(microtubule binding)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097009""(energy homeostasis)|go:""GO:0098793""(presynapse)|go:""GO:2000253""(positive regulation of feeding behavior)|interpro:IPR018808|interpro:IPR028565|interpro:IPR036168|interpro:IPR037984|mint:Q9BQI5|rcsb pdb:5AWR|rcsb pdb:5AWS|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:6A9Y|reactome:R-HSA-8856825|reactome:R-HSA-8856828"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:zFAutzD0AvL0d3TY1e1+TCO1vO09606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:44195D873EDE95F4|rigid:YAG9BJBlRwkseie/6x8blUdSKtM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UHA3	uniprotkb:Q5NHT8	intact:EBI-749321|uniprotkb:Q561V8|uniprotkb:Q8N6S8|uniprotkb:Q96B04|uniprotkb:Q96C76|uniprotkb:Q96HJ1|uniprotkb:B2RD72|ensembl:ENSP00000260443.4	intact:EBI-2806309	psi-mi:rlp24_human(display_long)|uniprotkb:Ribosomal protein L24-like(gene name synonym)|uniprotkb:RSL24D1(gene name)|psi-mi:RSL24D1(display_short)|uniprotkb:RPL24L(gene name synonym)|uniprotkb:My024(orf name)|uniprotkb:C15orf15(gene name synonym)|uniprotkb:Ribosomal L24 domain-containing protein 1(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299241|imex:IM-27563-251	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057388.1|ensembl:ENSG00000137876.11(gene)|ensembl:ENST00000260443.9(transcript)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005840""(ribosome)|go:""GO:0006412""(translation)|go:""GO:0042273""(ribosomal large subunit biogenesis)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:Q9UHA3|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:8FKP|rcsb pdb:8FKQ|rcsb pdb:8FKR|rcsb pdb:8FKS|rcsb pdb:8FKT|rcsb pdb:8FKU|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|rcsb pdb:8FKZ|rcsb pdb:8FL0|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FL9|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLC|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8FLF|rcsb pdb:8IDT|rcsb pdb:8IDY|rcsb pdb:8IE3|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8INK|rcsb pdb:8IPD|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR1|rcsb pdb:8IR3|panther:PTHR10792(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:dP0x5J6G4bPc/7sbV1LIxLNLDn09606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:6F83DD458A9D3DE5|rigid:mz0s1RhhNzph7wXZ5UPVDJ7gzH0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00422	uniprotkb:Q5NH45	intact:EBI-1044156|ensembl:ENSP00000475925.1|uniprotkb:Q2TTR4|uniprotkb:Q6IAW9|uniprotkb:Q8N606|uniprotkb:Q9UF14|uniprotkb:B2R494|uniprotkb:X6RAL5	intact:EBI-2796893|uniprotkb:A0A0G2RNJ2	psi-mi:sap18_human(display_long)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 38 protein(gene name synonym)|uniprotkb:2HOR0202(gene name synonym)|uniprotkb:SAP18(gene name)|psi-mi:SAP18(display_short)|uniprotkb:GIG38(orf name)	psi-mi:q5nh45_fratt(display_long)|uniprotkb:lon(gene name)|psi-mi:lon(display_short)|uniprotkb:ATP-dependent protease La(gene name synonym)|uniprotkb:FTT_0626(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299251|imex:IM-27563-649	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000150459.13(gene)|ensembl:ENST00000607003.5(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016604""(nuclear body)|go:""GO:0016607""(nuclear speck)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048025""(negative regulation of mRNA splicing, via spliceosome)|go:""GO:0061574""(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O00422|rcsb pdb:2HDE|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-72163|reactome:R-HSA-9679191|refseq:NP_005861.2|dip:DIP-33590N|panther:PTHR13082(orthology-group)"	"go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034605""(cellular response to heat)|go:""GO:0043565""(sequence-specific DNA binding)|interpro:IPR054594|refseq:YP_169647.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR027065|interpro:IPR027417|interpro:IPR027543|refseq:WP_003023412.1|mint:Q5NH45|interpro:IPR046336"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/26	rogid:eJoksFCc7vBoAjJEpnXJvc/yg+Q9606	rogid:VbLPJiXznE9s4Ww3dtsvWlgjMfM177416	intact-crc:13B2169168AEF7B8|rigid:n/L2CuQMX3C+Quke6CWeN6b1g4I	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96EB6	uniprotkb:Q5NEC5	intact:EBI-1802965|uniprotkb:Q2XNF6|uniprotkb:Q5JVQ0|uniprotkb:Q9GZR9|uniprotkb:Q9Y6F0|ensembl:ENSP00000212015.6	intact:EBI-22297545	psi-mi:sir1_human(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:SIRT1(gene name)|psi-mi:SIRT1(display_short)|uniprotkb:SIR2L1(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299331|imex:IM-27563-253	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001135970.1|refseq:NP_036370.2|ensembl:ENSG00000096717.12(gene)|ensembl:ENST00000212015.11(transcript)|go:""GO:0000012""(single strand break repair)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000183""(rDNA heterochromatin formation)|go:""GO:0000720""(pyrimidine dimer repair by nucleotide-excision repair)|go:""GO:0000731""(DNA synthesis involved in DNA repair)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000792""(heterochromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001542""(ovulation from ovarian follicle)|go:""GO:0001650""(fibrillar center)|go:""GO:0001678""(intracellular glucose homeostasis)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0002039""(p53 binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0004407""(histone deacetylase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005677""(chromatin silencing complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006346""(DNA methylation-dependent constitutive heterochromatin formation)|go:""GO:0006476""(protein deacetylation)|go:""GO:0006642""(triglyceride mobilization)|go:""GO:0006974""(DNA damage response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0007517""(muscle organ development)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010868""(negative regulation of triglyceride biosynthetic process)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0010883""(regulation of lipid storage)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016605""(PML body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0017136""(histone deacetylase activity, NAD-dependent)|go:""GO:0018394""(peptidyl-lysine acetylation)|go:""GO:0019213""(deacetylase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031393""(negative regulation of prostaglandin biosynthetic process)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031648""(protein destabilization)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0032041""(histone H3K14 deacetylase activity, NAD-dependent)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032868""(response to insulin)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0033210""(leptin-mediated signaling pathway)|go:""GO:0033553""(rDNA heterochromatin)|go:""GO:0033558""(protein lysine deacetylase activity)|go:""GO:0034391""(regulation of smooth muscle cell apoptotic process)|go:""GO:0034979""(NAD-dependent protein lysine deacetylase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035356""(intracellular triglyceride homeostasis)|go:""GO:0035358""(regulation of peroxisome proliferator activated receptor signaling pathway)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042326""(negative regulation of phosphorylation)|go:""GO:0042393""(histone binding)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042595""(behavioral response to starvation)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043398""(HLH domain binding)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0044321""(response to leptin)|go:""GO:0045348""(positive regulation of MHC class II biosynthetic process)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045722""(positive regulation of gluconeogenesis)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046015""(regulation of transcription by glucose)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0046872""(metal ion binding)|go:""GO:0046969""(histone H3K9 deacetylase activity, NAD-dependent)|go:""GO:0046970""(histone H4K16 deacetylase activity, NAD-dependent)|go:""GO:0050872""(white fat cell differentiation)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0051658""(maintenance of nucleus location)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055089""(fatty acid homeostasis)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0061773""(eNoSc complex)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070403""(NAD+ binding)|go:""GO:0070857""(regulation of bile acid biosynthetic process)|go:""GO:0070914""(UV-damage excision repair)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0090335""(regulation of brown fat cell differentiation)|go:""GO:0090400""(stress-induced premature senescence)|go:""GO:0097009""(energy homeostasis)|go:""GO:0097372""(histone H3K18 deacetylase activity, NAD-dependent)|go:""GO:0106230""(protein depropionylation)|go:""GO:0106231""(NAD-dependent protein-lysine depropionylase activity)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140765""(histone H3K56 deacetylase activity, NAD-dependent)|go:""GO:0140861""(DNA repair-dependent chromatin remodeling)|go:""GO:0140937""(histone H4K12 deacetylase activity, hydrolytic mechanism)|go:""GO:0141050""(histone H3K deacetylase activity)|go:""GO:0141208""(NAD-dependent protein lysine delactylase activity)|go:""GO:0141222""(histone H3K4 deacetylase activity, NAD-dependent)|go:""GO:0160012""(NAD-dependent histone decrotonylase activity)|go:""GO:0170012""(histone H3K18 decrotonylase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901797""(negative regulation of signal transduction by p53 class mediator)|go:""GO:1901984""(negative regulation of protein acetylation)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902424""(negative regulation of attachment of mitotic spindle microtubules to kinetochore)|go:""GO:1904179""(positive regulation of adipose tissue development)|go:""GO:1990254""(keratin filament binding)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000111""(positive regulation of macrophage apoptotic process)|go:""GO:2000481""(positive regulation of cAMP-dependent protein kinase activity)|go:""GO:2000655""(negative regulation of cellular response to testosterone stimulus)|go:""GO:2000757""(negative regulation of peptidyl-lysine acetylation)|go:""GO:2000773""(negative regulation of cellular senescence)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|interpro:IPR050134|mint:Q96EB6|rcsb pdb:4I5I|rcsb pdb:4IF6|rcsb pdb:4IG9|rcsb pdb:4KXQ|rcsb pdb:4ZZH|rcsb pdb:4ZZI|rcsb pdb:4ZZJ|rcsb pdb:5BTR|rcsb pdb:8ANB|reactome:R-HSA-3371453|reactome:R-HSA-400253|reactome:R-HSA-427359|reactome:R-HSA-9617629|reactome:R-HSA-9707616|reactome:R-HSA-9841922|reactome:R-HSA-9854907|reactome:R-HSA-9856649|panther:PTHR11085(orthology-group)|refseq:NP_001300978.1|dip:DIP-29757N"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/24	rogid:h3zVepuhRhzlINCluVuAn71Btjc9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:C164416497947E83|rigid:I4Zj7RMr39vsKZkVEh+GkuYID8k	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99496	uniprotkb:Q5NEV0	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480.3|ensembl:ENSP00000520426.1	intact:EBI-22299174|uniprotkb:A0A0G2RP53	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	"psi-mi:q5nev0_fratt(display_long)|uniprotkb:relA(gene name)|psi-mi:relA(display_short)|uniprotkb:""(p)ppGpp synthase""(gene name synonym)|uniprotkb:""ATP:GTP 3'-pyrophosphotransferase""(gene name synonym)|uniprotkb:ppGpp synthase I(gene name synonym)|uniprotkb:FTT_1508c(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299191|imex:IM-27563-319	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000121481.12(gene)|ensembl:ENST00000367510.8(transcript)|ensembl:ENST00000715230.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000791""(euchromatin)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001739""(sex chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0007281""(germ cell development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0010467""(gene expression)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0071339""(MLL1 complex)|go:""GO:0071535""(RING-like zinc finger domain binding)|go:""GO:0140862""(histone H2AK119 ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|rcsb pdb:8GRM|rcsb pdb:8PP7|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|panther:PTHR46076(orthology-group)"	"go:""GO:0005525""(GTP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0008728""(GTP diphosphokinase activity)|go:""GO:0008893""(""guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"")|go:""GO:0015969""(guanosine tetraphosphate metabolic process)|go:""GO:0016301""(kinase activity)|go:""GO:0042594""(response to starvation)|refseq:WP_003025932.1|refseq:YP_170442.1|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004811(RelA/SpoT protein)|interpro:IPR007685(RelA/SpoT)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|interpro:IPR033655|mint:Q5NEV0|interpro:IPR043519"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/27	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:j8MreXRGyjWTWSOsZagqQx0cTxU177416	intact-crc:5D35A002A30EE981|rigid:F8djVJ3FV7Ym6p0ne0SpVsSjb3E	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99496	uniprotkb:Q5NES6	intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480.3|ensembl:ENSP00000520426.1	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299201|imex:IM-27563-411	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000121481.12(gene)|ensembl:ENST00000367510.8(transcript)|ensembl:ENST00000715230.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000791""(euchromatin)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001739""(sex chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0007281""(germ cell development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0010467""(gene expression)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0031519""(PcG protein complex)|go:""GO:0035102""(PRC1 complex)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0071339""(MLL1 complex)|go:""GO:0071535""(RING-like zinc finger domain binding)|go:""GO:0140862""(histone H2AK119 ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|rcsb pdb:8GRM|rcsb pdb:8PP7|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|panther:PTHR46076(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/27	rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:3776687731D4F0EB|rigid:VsdFmBhcIj4jeTGuJWyeqGaH4Tk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P52788	uniprotkb:Q5NGJ5	intact:EBI-724744|uniprotkb:A6NHA7|uniprotkb:A6NI34|uniprotkb:O00544|uniprotkb:Q9UQS1|uniprotkb:B2R9M0|ensembl:ENSP00000385746.2	intact:EBI-22297738|uniprotkb:A0A0G2RPF6	psi-mi:spsy_human(display_long)|uniprotkb:Spermidine aminopropyltransferase(gene name synonym)|uniprotkb:SMS(gene name)|psi-mi:SMS(display_short)	psi-mi:q5ngj5_fratt(display_long)|uniprotkb:FTT_0842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299381|imex:IM-27563-581	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:3063""|ensembl:ENSG00000102172.16(gene)|ensembl:ENST00000404933.7(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006555""(methionine metabolic process)|go:""GO:0006595""(polyamine metabolic process)|go:""GO:0006597""(spermine biosynthetic process)|go:""GO:0016768""(spermine synthase activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR015576(Spermine synthase-related)|interpro:IPR029063|interpro:IPR030373|interpro:IPR030374|interpro:IPR035246|interpro:IPR037163|interpro:IPR040900|mint:P52788|rcsb pdb:3C6K|rcsb pdb:3C6M|reactome:R-HSA-351202|refseq:NP_001245352.1|refseq:NP_004586.2|panther:PTHR46315(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|interpro:IPR050330|refseq:WP_003020808.1|refseq:YP_169847.1|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|mint:Q5NGJ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:RxMB1ienUWc30YDh7Zz7V49PjdQ9606	rogid:/Dq7r5H2A4RbaDlrrHYQHMOGtbc177416	intact-crc:91F606E40C6B08A1|rigid:zhHYorauLcXlAAd2HzGdjCGXxFw	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15269	uniprotkb:Q5NEC5	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|intact:EBI-25630596|uniprotkb:Q96IX6|ensembl:ENSP00000262554.2	intact:EBI-22297545	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299505|imex:IM-27563-585	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090054.16(gene)|ensembl:ENST00000262554.7(transcript)|go:""GO:0004758""(serine C-palmitoyltransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006665""(sphingolipid metabolic process)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0017059""(serine palmitoyltransferase complex)|go:""GO:0030148""(sphingolipid biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0046511""(sphinganine biosynthetic process)|go:""GO:0046512""(sphingosine biosynthetic process)|go:""GO:0046513""(ceramide biosynthetic process)|go:""GO:1904504""(positive regulation of lipophagy)|go:""GO:1904649""(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR050087|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|rcsb pdb:7YIU|rcsb pdb:7YIY|rcsb pdb:7YJ1|rcsb pdb:7YJ2|reactome:R-HSA-1660661|refseq:NP_001268232.1|refseq:NP_006406.1|refseq:NP_847894.1|dip:DIP-45626N|efo:""Orphanet:300605""|efo:""Orphanet:36386""|panther:PTHR13693(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/01	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:C54622C0DD81D913|rigid:hv1mta0vWls5vBmbmM0WFqeKDlA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43791	uniprotkb:Q5NEM9	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327.2|ensembl:ENSP00000377001.2|ensembl:ENSP00000420908.1|ensembl:ENSP00000424119.2|ensembl:ENSP00000425905.1|ensembl:ENSP00000426986.2|ensembl:ENSP00000499562.1	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299485|imex:IM-27563-583	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:662175""|efo:""Orphanet:662179""|dip:DIP-50517N|ensembl:ENSG00000121067.19(gene)|ensembl:ENST00000347630.6(transcript)|ensembl:ENST00000393328.6(transcript)|ensembl:ENST00000503676.5(transcript)|ensembl:ENST00000504102.6(transcript)|ensembl:ENST00000509079.6(transcript)|ensembl:ENST00000514121.6(transcript)|ensembl:ENST00000665825.1(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0016607""(nuclear speck)|go:""GO:0030162""(regulation of proteolysis)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0140678""(molecular function inhibitor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7KLZ|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|rcsb pdb:8DWS|rcsb pdb:8DWT|rcsb pdb:8DWU|rcsb pdb:8DWV|reactome:R-HSA-5632684|refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|refseq:XP_016880693.1|panther:PTHR24413(orthology-group)|ensembl:ENSP00000240327.2|ensembl:ENSP00000377001.2|ensembl:ENSP00000420908.1|ensembl:ENSP00000425905.1|ensembl:ENSP00000426986.2|ensembl:ENSP00000424119.2|ensembl:ENSP00000499562.1"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/25	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:E0D00C65DE750FFE|rigid:4aHVjd+yYcgnVK/kEdsPS3Qa3n4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6M5	uniprotkb:Q5NHH2	intact:EBI-10982148|uniprotkb:Q0VAK9|uniprotkb:Q9BZF6|ensembl:ENSP00000355968.4	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:znt1_human(display_long)|uniprotkb:Zinc transporter 1(gene name synonym)|uniprotkb:SLC30A1(gene name)|psi-mi:SLC30A1(display_short)|uniprotkb:Solute carrier family 30 member 1(gene name synonym)|uniprotkb:ZNT1(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299371|imex:IM-27563-501	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067017.2|ensembl:ENSG00000170385.10(gene)|ensembl:ENST00000367001.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005385""(zinc ion transmembrane transporter activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006829""(zinc ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0010312""(detoxification of zinc ion)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0030315""(T-tubule)|go:""GO:0030425""(dendrite)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0046872""(metal ion binding)|go:""GO:0046929""(negative regulation of neurotransmitter secretion)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0062111""(zinc ion import into organelle)|go:""GO:0070509""(calcium ion import)|go:""GO:0070574""(cadmium ion transmembrane transport)|go:""GO:0071577""(zinc ion transmembrane transport)|go:""GO:0071584""(negative regulation of zinc ion transmembrane import)|go:""GO:0071585""(detoxification of cadmium ion)|go:""GO:0090281""(negative regulation of calcium ion import)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0099573""(glutamatergic postsynaptic density)|go:""GO:0140826""(""zinc:proton antiporter activity"")|go:""GO:0140882""(zinc export across plasma membrane)|go:""GO:1902897""(regulation of postsynaptic density protein 95 clustering)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|mint:Q9Y6M5|rcsb pdb:8J2G|rcsb pdb:8ZSB|rcsb pdb:8ZSZ|reactome:R-HSA-435368|panther:PTHR45820(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:XL8LmzhYwIWnN1yPFHnDkoJg2TE9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:B1086630778E66E5|rigid:dFffFy2EtPfPdZ/dGte+T4Nuhk4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60271	uniprotkb:Q5NES6	intact:EBI-1023301|uniprotkb:A6H8U5|intact:EBI-2560890|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|ensembl:ENSP00000262013.7	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299440|imex:IM-27563-423	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294.22(gene)|ensembl:ENST00000262013.12(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019894""(kinesin binding)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032418""(lysosome localization)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903860""(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|panther:PTHR13886(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:13146698D948F630|rigid:zyy5Kas8xRHxcbbVwsOgq/tRZ6w	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08579	uniprotkb:Q5NG28	intact:EBI-1053651|uniprotkb:Q9UJD4|uniprotkb:B2R7J3|uniprotkb:D3DW21|ensembl:ENSP00000246071.6|ensembl:ENSP00000367178.5	intact:EBI-2802768|uniprotkb:A0A0G2RPI9	psi-mi:ru2b_human(display_long)|uniprotkb:SNRPB2(gene name)|psi-mi:SNRPB2(display_short)	psi-mi:q5ng28_fratt(display_long)|uniprotkb:dacD(gene name)|psi-mi:dacD(display_short)|uniprotkb:FTT_1029(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299401|imex:IM-27563-51	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003083.1|refseq:NP_937863.1|ensembl:ENSG00000125870.11(gene)|ensembl:ENST00000246071.8(transcript)|ensembl:ENST00000377943.9(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0001650""(fibrillar center)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005684""(U2-type spliceosomal complex)|go:""GO:0005685""(U1 snRNP)|go:""GO:0005686""(U2 snRNP)|go:""GO:0016607""(nuclear speck)|go:""GO:0030619""(U1 snRNA binding)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0070990""(snRNP binding)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1903241""(U2-type prespliceosome assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034562|interpro:IPR034564|interpro:IPR035979|mint:P08579|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7EVO|rcsb pdb:7VPX|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8HK1|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8QO9|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RM5|rcsb pdb:9FMD|reactome:R-HSA-72163|panther:PTHR10501(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015956(Penicillin-binding protein-associated)|interpro:IPR018044|interpro:IPR012907(Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal)|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:YP_170014.1|refseq:WP_003021136.1|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|rcsb pdb:6OSU|mint:Q5NG28|interpro:IPR037167"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:AzDL3wfFG4HmOfTs8NJL6bWjgrc9606	rogid:EYTPcD8JUkej9Gvps0ogQD5aQ1c177416	intact-crc:72D72799D51F2FEF|rigid:xFLV/LCIJU97ZNZBuENWlbHe0Uw	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13425	uniprotkb:Q5NIG9	intact:EBI-80411|uniprotkb:Q9BY09|ensembl:ENSP00000338191.4	intact:EBI-22299411|uniprotkb:A0A0G2RMS2	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:q5nig9_fratt(display_long)|uniprotkb:FTT_0103c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299420|imex:IM-27563-503	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006741.1|panther:PTHR10554(orthology-group)|ensembl:ENSG00000168807.17(gene)|ensembl:ENST00000336278.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016020""(membrane)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045202""(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|interpro:IPR055108|mint:Q13425|rcsb pdb:2VRF"	refseq:WP_003019536.1|refseq:YP_169173.1|interpro:IPR038721|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|mint:Q5NIG9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rogid:TeoOWdARAaB8os8ExfibIgVqyp0177416	intact-crc:DEFD6F45687C075C|rigid:WTw/QGXgGHDjf/40TXajWdlHJCw	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43308	uniprotkb:Q5NEC5	intact:EBI-2822012|uniprotkb:Q5VY96|uniprotkb:Q53HI0|uniprotkb:B2R9K9|uniprotkb:Q5VY95|uniprotkb:Q9BWE4|uniprotkb:Q6IB31|uniprotkb:D3DVA7|ensembl:ENSP00000295702.4|ensembl:ENSP00000434306.1	intact:EBI-22297545	psi-mi:ssrb_human(display_long)|uniprotkb:SSR2(gene name)|psi-mi:SSR2(display_short)|uniprotkb:TRAPB(gene name synonym)|uniprotkb:Signal sequence receptor subunit beta(gene name synonym)|uniprotkb:HSD25(orf name)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299535|imex:IM-27563-509	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003136.1|ensembl:ENSG00000163479.14(gene)|ensembl:ENST00000295702.9(transcript)|ensembl:ENST00000480567.5(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006613""(cotranslational protein targeting to membrane)|go:""GO:0016020""(membrane)|interpro:IPR008856(Translocon-associated beta)|mint:P43308|rcsb pdb:8B6L|reactome:R-HSA-1799339|dip:DIP-60652N|panther:PTHR12861(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:+cohFHCuFzTjNpAVIxzLWj0ReK89606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:96AF8DF4C3748A37|rigid:xA58uC92hOl45KsjFj+Q/7JF+Pc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZUB0	uniprotkb:Q5NIP8	intact:EBI-22299460|ensembl:ENSP00000488251.1|intact:EBI-28977127|uniprotkb:A0A0J9YX51	intact:EBI-2796698	psi-mi:s31d4_human(display_long)|uniprotkb:Protein FAM75D4(gene name synonym)|uniprotkb:SPATA31D4(gene name)|psi-mi:SPATA31D4(display_short)|uniprotkb:FAM75D4(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299475|imex:IM-27563-507	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000189357.9(gene)|ensembl:ENST00000419782.5(transcript)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016020""(membrane)|go:""GO:0030154""(cell differentiation)|interpro:IPR027970|interpro:IPR039509|mint:Q6ZUB0|refseq:NP_001138669.1"	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:+h9+YZ8JG6iIjOu0kNge3LOj2BI9606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:23656150CD76D608|rigid:cgvstWuBRWJxbjUvdB0dbQdxAMk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75643	uniprotkb:Q5NEC5	intact:EBI-1045395|uniprotkb:O94884|uniprotkb:Q6PX59|uniprotkb:Q8NBE6|uniprotkb:Q96IF2|uniprotkb:Q9H7S0|uniprotkb:Q6NZY0|intact:EBI-1051631|ensembl:ENSP00000317123.5	intact:EBI-22297545	psi-mi:u520_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short)|uniprotkb:HELIC2(gene name synonym)|uniprotkb:KIAA0788(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)|uniprotkb:Activating signal cointegrator 1 complex subunit 3-like 1(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:ASCC3L1(gene name synonym)|uniprotkb:BRR2(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299391|imex:IM-27563-163	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:791""|dip:DIP-31659N|ensembl:ENSG00000144028.15(gene)|ensembl:ENST00000323853.10(transcript)|go:""GO:0000354""(cis assembly of pre-catalytic spliceosome)|go:""GO:0000388""(""spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)"")|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005682""(U5 snRNP)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071006""(U2-type catalytic step 1 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|interpro:IPR048863|interpro:IPR050474|mint:O75643|rcsb pdb:2Q0Z|rcsb pdb:3JCR|rcsb pdb:4F91|rcsb pdb:4F92|rcsb pdb:4F93|rcsb pdb:4KIT|rcsb pdb:5O9Z|rcsb pdb:5URJ|rcsb pdb:5URK|rcsb pdb:5URM|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8O|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|rcsb pdb:7OS1|rcsb pdb:7OS2|rcsb pdb:7PX3|rcsb pdb:7W5B|rcsb pdb:8BC8|rcsb pdb:8BC9|rcsb pdb:8BCA|rcsb pdb:8BCB|rcsb pdb:8BCC|rcsb pdb:8BCD|rcsb pdb:8BCE|rcsb pdb:8BCF|rcsb pdb:8BCG|rcsb pdb:8BCH|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0W|rcsb pdb:8Q7Q|rcsb pdb:8Q7V|rcsb pdb:8Q7W|rcsb pdb:8Q7X|rcsb pdb:8Q91|rcsb pdb:8QO9|rcsb pdb:8QOZ|rcsb pdb:8QP9|rcsb pdb:8QPA|rcsb pdb:8QPB|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RC0|rcsb pdb:8RM5|rcsb pdb:8Y6O|rcsb pdb:9FMD|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_054733.2|refseq:XP_016859092.1|panther:PTHR24075(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:2ZAcbMfMlk2xWWAiy7MeCL0CHtM9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:31D8E340A97DC4C4|rigid:Ir0mUla3nn9CQSkwL26U5PSEJMY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UHB9	uniprotkb:Q5NFC5	intact:EBI-1048560|uniprotkb:Q8NCJ4|uniprotkb:Q8WUK2|ensembl:ENSP00000312066.1|uniprotkb:B3KUU5|uniprotkb:B3KWY7|uniprotkb:G3V1U4	intact:EBI-22298320|uniprotkb:A0A0G2RPT0	psi-mi:srp68_human(display_long)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein(gene name synonym)	psi-mi:q5nfc5_fratt(display_long)|uniprotkb:General secretion pathway protein H(gene name synonym)|uniprotkb:FTT_1314c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299515|imex:IM-27563-587	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001247431.1|refseq:NP_001247432.1|refseq:NP_055045.2|ensembl:ENSG00000167881.15(gene)|ensembl:ENST00000307877.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005047""(signal recognition particle binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005786""(signal recognition particle, endoplasmic reticulum targeting)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005925""(focal adhesion)|go:""GO:0006614""(SRP-dependent cotranslational protein targeting to membrane)|go:""GO:0008312""(7S RNA binding)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030942""(endoplasmic reticulum signal peptide binding)|go:""GO:0048500""(signal recognition particle)|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|mint:Q9UHB9|rcsb pdb:4P3E|rcsb pdb:4P3F|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:7NFX|rcsb pdb:7QWQ|rcsb pdb:8QVW|reactome:R-HSA-1799339|dip:DIP-50905N|panther:PTHR12860(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0015627""(type II protein secretion system complex)|go:""GO:0015628""(protein secretion by the type II secretion system)|interpro:IPR045584|refseq:WP_003022044.1|refseq:YP_170267.1|mint:Q5NFC5|interpro:IPR022346"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/01	rogid:8WwEMUV+QzJGJ6G7xufvSibYTSY9606	rogid:0X6MsYyGE7Tjd9I6bLIdEfgErGo177416	intact-crc:8D655F20FF085D73|rigid:dreIDD5l8ftVowaSW+i4zxjMdPY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6Q2	uniprotkb:Q5NFP9	intact:EBI-2821664|uniprotkb:Q96JE3|uniprotkb:Q9BYX3|uniprotkb:A8MXJ1|uniprotkb:B5MCF5|uniprotkb:B7ZL16|uniprotkb:A0A0A6YYH4|ensembl:ENSP00000384615.1|ensembl:ENSP00000385273.1|ensembl:ENSP00000497745.1	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:ston1_human(display_long)|uniprotkb:STON1(gene name)|psi-mi:STON1(display_short)|uniprotkb:SALF(gene name synonym)|uniprotkb:SBLF(gene name synonym)|uniprotkb:STN1(gene name synonym)|uniprotkb:Stoned B-like factor(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299555|imex:IM-27563-257	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001185524.1|refseq:NP_006864.2|refseq:NP_001185523.1|refseq:NP_001185522.1|ensembl:ENSG00000243244.7(gene)|ensembl:ENST00000404752.6(transcript)|ensembl:ENST00000406226.1(transcript)|ensembl:ENST00000649748.1(transcript)|go:""GO:0006929""(substrate-dependent cell migration)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0031252""(cell leading edge)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0042995""(cell projection)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097178""(ruffle assembly)|go:""GO:0120181""(focal adhesion disassembly)|interpro:IPR012320(Stonin homology)|interpro:IPR017110(Stonin)|interpro:IPR028565|interpro:IPR036168|interpro:IPR050431|mint:Q9Y6Q2|reactome:R-HSA-8856825|reactome:R-HSA-8856828|panther:PTHR10529(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:O2+Gya+wEzoNx284WvUMRjezRZY9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:8D5C880F84376E8B|rigid:EybOkzfJZBsi0cKNjA8RFKJ+ShA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75886	uniprotkb:Q5NGJ5	intact:EBI-373258|uniprotkb:Q7LDQ0|uniprotkb:Q9UF58|uniprotkb:A8K8A0|uniprotkb:D3DPA1|ensembl:ENSP00000263904.4	intact:EBI-22297738|uniprotkb:A0A0G2RPF6	psi-mi:stam2_human(display_long)|uniprotkb:STAM2(gene name)|psi-mi:STAM2(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Hrs-binding protein(gene name synonym)	psi-mi:q5ngj5_fratt(display_long)|uniprotkb:FTT_0842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299545|imex:IM-27563-653	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005834.4|ensembl:ENSG00000115145.10(gene)|ensembl:ENST00000263904.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0016236""(macroautophagy)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0031901""(early endosome membrane)|go:""GO:0033565""(ESCRT-0 complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0090148""(membrane fission)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035675|interpro:IPR036028|interpro:IPR047493|interpro:IPR050670|mint:O75886|rcsb pdb:1X2Q|rcsb pdb:1X5B|rcsb pdb:2L0T|rcsb pdb:5CRV|rcsb pdb:5IXF|reactome:R-HSA-182971|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|panther:PTHR45929(orthology-group)"	"go:""GO:0009279""(cell outer membrane)|interpro:IPR050330|refseq:WP_003020808.1|refseq:YP_169847.1|interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR036737|mint:Q5NGJ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:e5brcAWS5So29SdnZV3cAm/dZAk9606	rogid:/Dq7r5H2A4RbaDlrrHYQHMOGtbc177416	intact-crc:EEF8AFE9BCCA323E|rigid:58aTg0ER7BPHL2cK7xE36a5ncp0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43609	uniprotkb:Q5NEQ5	intact:EBI-3866665|uniprotkb:Q6PNE0|uniprotkb:D3DNX6|ensembl:ENSP00000343785.1|ensembl:ENSP00000377871.2|ensembl:ENSP00000480540.1|ensembl:ENSP00000481675.1|ensembl:ENSP00000498292.1	intact:EBI-2808269|uniprotkb:A0A0G2RQ71	psi-mi:spy1_human(display_long)|uniprotkb:SPRY1(gene name)|psi-mi:SPRY1(display_short)	psi-mi:q5neq5_fratt(display_long)|uniprotkb:Polyphosphate kinase PPK2(gene name synonym)|uniprotkb:FTT_1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299495|imex:IM-27563-651	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005832.1|refseq:NP_955359.1|refseq:NP_001244967.1|refseq:NP_001244968.1|refseq:XP_005262743.1|ensembl:ENSG00000164056.11(gene)|ensembl:ENST00000339241.1(transcript)|ensembl:ENST00000394339.2(transcript)|ensembl:ENST00000610581.4(transcript)|ensembl:ENST00000622283.1(transcript)|ensembl:ENST00000651917.1(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0001656""(metanephros development)|go:""GO:0001657""(ureteric bud development)|go:""GO:0001759""(organ induction)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0040037""(negative regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0046580""(negative regulation of Ras protein signal transduction)|go:""GO:0048513""(animal organ development)|go:""GO:0051387""(negative regulation of neurotrophin TRK receptor signaling pathway)|go:""GO:0060449""(bud elongation involved in lung branching)|go:""GO:0060940""(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:1902747""(negative regulation of lens fiber cell differentiation)|interpro:IPR007875(Sprouty)|interpro:IPR051192|mint:O43609|reactome:R-HSA-182971|refseq:XP_016863124.1|panther:PTHR12365(orthology-group)"	"interpro:IPR016898(Polyphosphate kinase 2, predicted)|interpro:IPR022488|interpro:IPR022486|refseq:YP_170487.1|refseq:WP_003014894.1|interpro:IPR027417|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0046872""(metal ion binding)|rcsb pdb:4YEG|rcsb pdb:5LL0|rcsb pdb:5LLB|rcsb pdb:5LLF|mint:Q5NEQ5"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:tbucIEQYibDQbBC1xVIZVDH2nIY9606	rogid:3hIShFXVmkZdI9gV6zbu32j30jM177416	intact-crc:6F7BE55AB18DE869|rigid:F/4fRsYcbIoeFYaaXW9Ni4LyIUs	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86U32	uniprotkb:Q5NEC5	intact:EBI-2562876	intact:EBI-22297545	psi-mi:q86u32_human(display_long)|uniprotkb:SFRS5(gene name)|psi-mi:SFRS5(display_short)|uniprotkb:hCG_21965(orf name)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299525|imex:IM-27563-323	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000504(RNA recognition motif, RNP-1)|go:""GO:0003723""(RNA binding)|interpro:IPR050374|mint:Q86U32|refseq:XP_016877083.1|interpro:IPR035979|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:fsV1/8Zs2cz6wdZ6+6v8oU/5Fsg9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:1DDD3D80522D37F1|rigid:/j1pKQ1khZPva9+bwKufFfArnS0	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6M5	uniprotkb:Q5NIP8	intact:EBI-10982148|uniprotkb:Q0VAK9|uniprotkb:Q9BZF6|ensembl:ENSP00000355968.4	intact:EBI-2796698	psi-mi:znt1_human(display_long)|uniprotkb:Zinc transporter 1(gene name synonym)|uniprotkb:SLC30A1(gene name)|psi-mi:SLC30A1(display_short)|uniprotkb:Solute carrier family 30 member 1(gene name synonym)|uniprotkb:ZNT1(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299361|imex:IM-27563-579	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067017.2|ensembl:ENSG00000170385.10(gene)|ensembl:ENST00000367001.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005385""(zinc ion transmembrane transporter activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006829""(zinc ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0010312""(detoxification of zinc ion)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0030315""(T-tubule)|go:""GO:0030425""(dendrite)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0046872""(metal ion binding)|go:""GO:0046929""(negative regulation of neurotransmitter secretion)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0062111""(zinc ion import into organelle)|go:""GO:0070509""(calcium ion import)|go:""GO:0070574""(cadmium ion transmembrane transport)|go:""GO:0071577""(zinc ion transmembrane transport)|go:""GO:0071584""(negative regulation of zinc ion transmembrane import)|go:""GO:0071585""(detoxification of cadmium ion)|go:""GO:0090281""(negative regulation of calcium ion import)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0099092""(postsynaptic density, intracellular component)|go:""GO:0099573""(glutamatergic postsynaptic density)|go:""GO:0140826""(""zinc:proton antiporter activity"")|go:""GO:0140882""(zinc export across plasma membrane)|go:""GO:1902897""(regulation of postsynaptic density protein 95 clustering)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|mint:Q9Y6M5|rcsb pdb:8J2G|rcsb pdb:8ZSB|rcsb pdb:8ZSZ|reactome:R-HSA-435368|panther:PTHR45820(orthology-group)"	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:XL8LmzhYwIWnN1yPFHnDkoJg2TE9606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:75EA61943CD39116|rigid:B7pQk/4fEnmicMMXpreq6kLtzAo	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60271	uniprotkb:Q5NFC5	intact:EBI-1023301|uniprotkb:A6H8U5|intact:EBI-2560890|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|ensembl:ENSP00000262013.7	intact:EBI-22298320|uniprotkb:A0A0G2RPT0	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:q5nfc5_fratt(display_long)|uniprotkb:General secretion pathway protein H(gene name synonym)|uniprotkb:FTT_1314c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299450|imex:IM-27563-255	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294.22(gene)|ensembl:ENST00000262013.12(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019894""(kinesin binding)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032418""(lysosome localization)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903860""(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|panther:PTHR13886(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0015627""(type II protein secretion system complex)|go:""GO:0015628""(protein secretion by the type II secretion system)|interpro:IPR045584|refseq:WP_003022044.1|refseq:YP_170267.1|mint:Q5NFC5|interpro:IPR022346"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:0X6MsYyGE7Tjd9I6bLIdEfgErGo177416	intact-crc:1044CAB8A028AC26|rigid:D7wLXIlyGZP5ikX66lgH6A10QsY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HBV2	uniprotkb:Q5NFP9	intact:EBI-17498703|ensembl:ENSP00000237201.1	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:saca1_human(display_long)|uniprotkb:Sperm acrosomal membrane-associated protein 32(gene name synonym)|uniprotkb:SPACA1(gene name)|psi-mi:SPACA1(display_short)|uniprotkb:SAMP32(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299430|imex:IM-27563-505	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_112222.1|panther:PTHR47223(orthology-group)|ensembl:ENSG00000118434.9(gene)|ensembl:ENST00000237201.2(transcript)|go:""GO:0001675""(acrosome assembly)|go:""GO:0002079""(inner acrosomal membrane)|go:""GO:0002080""(acrosomal membrane)|interpro:IPR037878|mint:Q9HBV2"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:En3NT4ITqXIWX5PuoJxbbDDx5Fw9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:AA9709AF13070CD5|rigid:P8HVpE4ru8roSRi4oXGxLSovpEk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P55061	uniprotkb:Q5NFC5	intact:EBI-1045825|uniprotkb:O14938|uniprotkb:Q643A7|uniprotkb:Q96J50|uniprotkb:F8W034|uniprotkb:B2R5M4|ensembl:ENSP00000267115.5|ensembl:ENSP00000378454.4|ensembl:ENSP00000448036.1|ensembl:ENSP00000450158.2	intact:EBI-22298320|uniprotkb:A0A0G2RPT0	psi-mi:bi1_human(display_long)|uniprotkb:Testis-enhanced gene transcript protein(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 6(gene name synonym)|uniprotkb:TMBIM6(gene name)|psi-mi:TMBIM6(display_short)|uniprotkb:BI1(gene name synonym)|uniprotkb:TEGT(gene name synonym)	psi-mi:q5nfc5_fratt(display_long)|uniprotkb:General secretion pathway protein H(gene name synonym)|uniprotkb:FTT_1314c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299605|imex:IM-27563-511	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001092046.1|refseq:NP_003208.2|ensembl:ENSG00000139644.13(gene)|ensembl:ENST00000267115.10(transcript)|ensembl:ENST00000395006.8(transcript)|ensembl:ENST00000549385.5(transcript)|ensembl:ENST00000552370.5(transcript)|go:""GO:0002638""(negative regulation of immunoglobulin production)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006914""(autophagy)|go:""GO:0010523""(negative regulation of calcium ion transport into cytosol)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0033119""(negative regulation of RNA splicing)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0036483""(neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0060698""(endoribonuclease inhibitor activity)|go:""GO:0060702""(negative regulation of endoribonuclease activity)|go:""GO:1902065""(response to L-glutamate)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903298""(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|interpro:IPR006213(Bax inhibitor 1, conserved site)|interpro:IPR006214(Protein of unknown function UPF0005)|mint:P55061|refseq:XP_005269183.1|panther:PTHR23291(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0015627""(type II protein secretion system complex)|go:""GO:0015628""(protein secretion by the type II secretion system)|interpro:IPR045584|refseq:WP_003022044.1|refseq:YP_170267.1|mint:Q5NFC5|interpro:IPR022346"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:l3wlIZarKWk471gkb6A5Jy/gN/U9606	rogid:0X6MsYyGE7Tjd9I6bLIdEfgErGo177416	intact-crc:945F8B942F66AD29|rigid:DTnEn9LiWZ7OE6c/oUTn1ImM87A	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P23193	uniprotkb:Q5NEC5	intact:EBI-2608271|uniprotkb:A6NF25|uniprotkb:A8K339|uniprotkb:Q15563|uniprotkb:Q6FG87|ensembl:ENSP00000428426.2	intact:EBI-22297545	psi-mi:tcea1_human(display_long)|uniprotkb:TCEA1(gene name)|psi-mi:TCEA1(display_short)|uniprotkb:GTF2S(gene name synonym)|uniprotkb:TFIIS(gene name synonym)|uniprotkb:Transcription elongation factor S-II protein 1(gene name synonym)|uniprotkb:Transcription elongation factor TFIIS.o(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299595|imex:IM-27563-655	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006747.1|refseq:NP_958845.1|mint:P23193|ensembl:ENSG00000187735.16(gene)|ensembl:ENST00000521604.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005669""(transcription factor TFIID complex)|go:""GO:0005730""(nucleolus)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR006289(Transcription elongation factor, TFIIS)|interpro:IPR017923|interpro:IPR035100|interpro:IPR035441|interpro:IPR036575|rcsb pdb:1TFI|rcsb pdb:3NDQ|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:6O9L|rcsb pdb:6ZUY|rcsb pdb:6ZV4|rcsb pdb:7CNF|rcsb pdb:7UNC|rcsb pdb:7UND|rcsb pdb:8A40|rcsb pdb:8UIS|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-48480N|panther:PTHR11477(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/28	rogid:88QvzePEd32tHYxrij2EoOYkaLk9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:63C19A271871BC6B|rigid:fDiYjn8+n0fUIoaFF9DYkLy2Hss	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P82094	uniprotkb:Q5NEM9	intact:EBI-949763|uniprotkb:Q17R87|uniprotkb:B7ZLJ2|uniprotkb:Q59GK0|ensembl:ENSP00000381567.2	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:tmf1_human(display_long)|uniprotkb:TMF1(gene name)|psi-mi:TMF1(display_short)|uniprotkb:Androgen receptor coactivator 160 kDa protein(gene name synonym)|uniprotkb:ARA160(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 160 kDa(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299675|imex:IM-27563-59	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009045.2|refseq:XP_011532358.1|dip:DIP-5933N|ensembl:ENSG00000144747.17(gene)|ensembl:ENST00000398559.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001675""(acrosome assembly)|go:""GO:0001819""(positive regulation of cytokine production)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007289""(spermatid nucleus differentiation)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0032275""(luteinizing hormone secretion)|go:""GO:0033327""(Leydig cell differentiation)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1904036""(negative regulation of epithelial cell apoptotic process)|go:""GO:2000845""(positive regulation of testosterone secretion)|interpro:IPR022091|interpro:IPR022092|interpro:IPR052602|mint:P82094|reactome:R-HSA-6811440|panther:PTHR46515(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:F+z+GIH0PWbFoueklDHM/lj55MI9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:D5AC39424E827047|rigid:y4SOAjz1NF+La3vtuqG50KpHxvc	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94864	uniprotkb:Q5NEC5	intact:EBI-722912|uniprotkb:Q6IB21|uniprotkb:Q9H2T6|uniprotkb:B4E3W3|ensembl:ENSP00000336750.5	intact:EBI-22297545	psi-mi:st65g_human(display_long)|uniprotkb:SPTF-associated factor 65 gamma(gene name synonym)|uniprotkb:Suppressor of Ty 7-like(gene name synonym)|uniprotkb:Adenocarcinoma antigen ART1(gene name synonym)|uniprotkb:SUPT7L(gene name)|psi-mi:SUPT7L(display_short)|uniprotkb:KIAA0764(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299575|imex:IM-27563-165	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269658.1|refseq:NP_001269659.1|refseq:NP_001269660.1|refseq:NP_001269661.1|refseq:NP_055675.1|refseq:XP_005264729.1|ensembl:ENSG00000119760.16(gene)|ensembl:ENST00000337768.10(transcript)|go:""GO:0000124""(SAGA complex)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006282""(regulation of DNA repair)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051457""(maintenance of protein location in nucleus)|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR039460|mint:O94864|rcsb pdb:7KTR|rcsb pdb:7KTS|rcsb pdb:8H7G|reactome:R-HSA-3214847|panther:PTHR28598(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:v26YjDoNB/9ekC4xRZEm77Roruw9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:CE740FAF2E4F0D3C|rigid:d+dp4vRkpamy1raQeU7+ZW9YWwk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P26639	uniprotkb:Q5NEC5	intact:EBI-1042683|uniprotkb:Q96FP5|uniprotkb:Q9BWA6|uniprotkb:A8K8I1|uniprotkb:B4DEG8|ensembl:ENSP00000265112.3|ensembl:ENSP00000424387.1	intact:EBI-22297545	psi-mi:sytc_human(display_long)|uniprotkb:TARS1(gene name)|psi-mi:TARS1(display_short)|uniprotkb:TARS(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase 1(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299585|imex:IM-27563-53	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33364""|ensembl:ENSG00000113407.14(gene)|ensembl:ENST00000265112.8(transcript)|ensembl:ENST00000502553.5(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0004829""(threonine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006435""(threonyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR002320(Threonyl-tRNA synthetase, class IIa)|interpro:IPR004095(TGS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018163|interpro:IPR033728|interpro:IPR036621|interpro:IPR045864|interpro:IPR047246|mint:P26639|rcsb pdb:1WWT|rcsb pdb:4HWT|rcsb pdb:4P3N|rcsb pdb:4TTV|rcsb pdb:5XLN|reactome:R-HSA-379716|refseq:NP_001245366.1|refseq:NP_001245367.1|refseq:NP_689508.3|panther:PTHR11451(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:Z+rOaI1ZO1TQftfkRn1HhXUqDAk9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:CD52099EFA4D8D31|rigid:fBlzjDA/0yHn7quN2XOVBevTaIk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62995	uniprotkb:Q5NE77	intact:EBI-725485|uniprotkb:O15449|uniprotkb:Q15815|uniprotkb:Q64283|uniprotkb:B4DVK2|uniprotkb:D3DNU3|ensembl:ENSP00000416959.2	intact:EBI-22298544|uniprotkb:A0A0G2RPD5	psi-mi:tra2b_human(display_long)|uniprotkb:TRA2B(gene name)|psi-mi:TRA2B(display_short)|uniprotkb:SFRS10(gene name synonym)|uniprotkb:Transformer-2 protein homolog B(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 10(gene name synonym)	psi-mi:q5ne77_fratt(display_long)|uniprotkb:FTT_1776c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299705|imex:IM-27563-517	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004584.1|refseq:XP_005247760.1|refseq:NP_001230808.1|refseq:XP_011511374.1|refseq:XP_016862522.1|dip:DIP-42278N|ensembl:ENSG00000136527.19(gene)|ensembl:ENST00000453386.7(transcript)|go:""GO:0000375""(RNA splicing, via transesterification reactions)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021796""(cerebral cortex regionalization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:1990403""(embryonic brain development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR050441|mint:P62995|rcsb pdb:2CQC|rcsb pdb:2KXN|rcsb pdb:2RRA|rcsb pdb:2RRB|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|panther:PTHR48034(orthology-group)"	refseq:WP_003022749.1|refseq:YP_170665.1|interpro:IPR021952|mint:Q5NE77	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:6uZGeHEDlIVsb2uPeo+9NoR4tDw9606	rogid:fk9hxhaOluvQGV8dWTKghUWTN14177416	intact-crc:65034457E9502D64|rigid:NlrL5SWtpV69Mpi+0g146Nq+mVI	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95379	uniprotkb:Q5NHH2	intact:EBI-1049336|uniprotkb:Q9P1Q1|uniprotkb:Q9UER5|uniprotkb:Q9UP47|uniprotkb:B3KMI2|uniprotkb:B3KMH1|ensembl:ENSP00000421848.1|ensembl:ENSP00000422245.1|uniprotkb:B7Z713	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:tfip8_human(display_long)|uniprotkb:Head and neck tumor and metastasis-related protein(gene name synonym)|uniprotkb:TNF-induced protein GG2-1(gene name synonym)|uniprotkb:SCC-S2(gene name synonym)|uniprotkb:NF-kappa-B-inducible DED-containing protein(gene name synonym)|uniprotkb:MDC-3.13(gene name synonym)|uniprotkb:TNFAIP8(gene name)|psi-mi:TNFAIP8(display_short)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299695|imex:IM-27563-515	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001071122.1|refseq:NP_055165.2|refseq:NP_001273742.1|refseq:NP_001273743.1|refseq:NP_001273744.1|refseq:NP_001273746.1|ensembl:ENSG00000145779.8(gene)|ensembl:ENST00000503646.1(transcript)|ensembl:ENST00000504771.3(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|interpro:IPR008477(Protein of unknown function DUF758)|interpro:IPR038355|mint:O95379|reactome:R-HSA-1483255|panther:PTHR12757(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:kU/YcbWj8qTDg4s94mo4j41mT849606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:59D0CE2844CD924B|rigid:w4530qSldmD33sakelr89LaB5KM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H3N1	uniprotkb:Q5NHT8	intact:EBI-1051115|uniprotkb:Q8N487|uniprotkb:Q8NBN5|uniprotkb:Q9Y4T6|uniprotkb:B2R7A4|ensembl:ENSP00000393316.2	intact:EBI-2806309	psi-mi:tmx1_human(display_long)|uniprotkb:Transmembrane Trx-related protein(gene name synonym)|uniprotkb:TMX1(gene name)|psi-mi:TMX1(display_short)|uniprotkb:TXNDC1(gene name synonym)|uniprotkb:TMX(gene name synonym)|uniprotkb:TXNDC(gene name synonym)|uniprotkb:PSEC0085(orf name)|uniprotkb:UNQ235/PRO268(orf name)|uniprotkb:Thioredoxin domain-containing protein 1(gene name synonym)|uniprotkb:Protein disulfide-isomerase TMX1(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299685|imex:IM-27563-61	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_110382.3|ensembl:ENSG00000139921.13(gene)|ensembl:ENST00000457354.7(transcript)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0010868""(negative regulation of triglyceride biosynthetic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:1904294""(positive regulation of ERAD pathway)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR052454|mint:Q9H3N1|rcsb pdb:1X5E|panther:PTHR46107(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:ZJH5N22Dnrk+SXa3Ysqqfu1md/I9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:DC3505E71AFCF828|rigid:fbjnABfyEwWrzeUtXmAvwr/1U0c	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TBQ9	uniprotkb:Q5NEM9	intact:EBI-13383218|uniprotkb:Q0P692|ensembl:ENSP00000424707.1	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:kisha_human(display_long)|uniprotkb:TMEM167A(gene name)|psi-mi:TMEM167A(display_short)|uniprotkb:TMEM167(gene name synonym)|uniprotkb:Transmembrane protein 167(gene name synonym)|uniprotkb:Transmembrane protein 167A(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299645|imex:IM-27563-57	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR13229(orthology-group)|refseq:NP_777569.1|ensembl:ENSG00000174695.10(gene)|ensembl:ENST00000502346.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0009306""(protein secretion)|go:""GO:0045054""(constitutive secretory pathway)|go:""GO:0046907""(intracellular transport)|interpro:IPR009653(Protein of unknown function DUF1242)|interpro:IPR051523|mint:Q8TBQ9"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:2LP+Xrgp/MwE2xXWkUORDUaBvlw9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:475395A01C146168|rigid:czo3NkBdGEcrZ7yr+KCdHiesAYM	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A5PLL7	uniprotkb:Q5NEM9	intact:EBI-11337896|ensembl:ENSP00000360715.4	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:pdes1_human(display_long)|uniprotkb:PEDS1(gene name)|psi-mi:PEDS1(display_short)|uniprotkb:KUA(gene name synonym)|uniprotkb:PDES(gene name synonym)|uniprotkb:TMEM189(gene name synonym)|uniprotkb:Transmembrane protein 189(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299655|imex:IM-27563-513	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001155977.1|refseq:NP_954580.1|refseq:NP_954673.1|ensembl:ENSG00000240849.11(gene)|ensembl:ENST00000371652.9(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0008611""(ether lipid biosynthetic process)|go:""GO:0050207""(plasmanylethanolamine desaturase activity)|interpro:IPR019547|interpro:IPR052601|mint:A5PLL7|panther:PTHR48177(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:c7SCgDYXvW7UJ0yk8mQRuYTzEUs9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:E3B0CF2B878AD007|rigid:7tdvauM4ObauiUoRUWN7Zt332gE	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TBQ9	uniprotkb:Q5NHH2	intact:EBI-13383218|uniprotkb:Q0P692|ensembl:ENSP00000424707.1	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:kisha_human(display_long)|uniprotkb:TMEM167A(gene name)|psi-mi:TMEM167A(display_short)|uniprotkb:TMEM167(gene name synonym)|uniprotkb:Transmembrane protein 167(gene name synonym)|uniprotkb:Transmembrane protein 167A(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299635|imex:IM-27563-55	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR13229(orthology-group)|refseq:NP_777569.1|ensembl:ENSG00000174695.10(gene)|ensembl:ENST00000502346.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0009306""(protein secretion)|go:""GO:0045054""(constitutive secretory pathway)|go:""GO:0046907""(intracellular transport)|interpro:IPR009653(Protein of unknown function DUF1242)|interpro:IPR051523|mint:Q8TBQ9"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:2LP+Xrgp/MwE2xXWkUORDUaBvlw9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:2E9205C439CF526A|rigid:UlsIdFq9KJ3l0ZGoyBh6JdP97TY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UHN6	uniprotkb:Q5NEC5	intact:EBI-2876905|uniprotkb:B2RTQ6|uniprotkb:Q8NBP6|uniprotkb:Q5T841|uniprotkb:Q5T840|uniprotkb:Q9P2D5|uniprotkb:Q5T839|uniprotkb:Q5T838|uniprotkb:A6H8W9|ensembl:ENSP00000366243.4	intact:EBI-22297545	psi-mi:ceip2_human(display_long)|uniprotkb:CEMIP2(gene name)|psi-mi:CEMIP2(display_short)|uniprotkb:KIAA1412(gene name synonym)|uniprotkb:TMEM2(gene name synonym)|uniprotkb:Transmembrane protein 2(gene name synonym)|uniprotkb:Cell migration-inducing hyaluronidase 2(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299665|imex:IM-27563-167	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001129292.1|refseq:NP_037522.1|ensembl:ENSG00000135048.14(gene)|ensembl:ENST00000377044.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903670""(regulation of sprouting angiogenesis)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR019316|interpro:IPR039473|interpro:IPR039477|interpro:IPR052252|mint:Q9UHN6|rcsb pdb:8C6I|refseq:XP_005251926.1|panther:PTHR15535(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:LVdpEH7Df1biSXHseli56Y9l9XQ9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:9B147027D16311C8|rigid:62UerksbpDQqybOXc5gG12xkbEo	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49755	uniprotkb:Q5NIP8	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145.4	intact:EBI-2796698	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:q5nip8_fratt(display_long)|uniprotkb:FTT_0018(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299615|imex:IM-27563-327	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006818.3|ensembl:ENSG00000170348.9(gene)|ensembl:ENST00000303575.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0032732""(positive regulation of interleukin-1 production)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0035964""(COPI-coated vesicle budding)|go:""GO:0042470""(melanosome)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0048199""(vesicle targeting, to, from or within Golgi)|go:""GO:0048205""(COPI coating of Golgi vesicle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0070765""(gamma-secretase complex)|go:""GO:0106272""(protein localization to ERGIC)|go:""GO:0106273""(cytosol to ERGIC protein transport)|go:""GO:1902003""(regulation of amyloid-beta formation)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR22811(orthology-group)"	interpro:IPR050739|refseq:YP_169094.1|mint:Q5NIP8|interpro:IPR039562	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	rogid:zIvOdx6A89Zlpfvha/D/uwNsho4177416	intact-crc:69D9C0D83A08675B|rigid:0ay2XVeds2ihY+39cmOZO0rgvng	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UNK0	uniprotkb:Q5NES6	intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255.2	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299565|imex:IM-27563-325	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004844.1|ensembl:ENSG00000170310.15(gene)|ensembl:ENST00000306357.9(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0005484""(SNAP receptor activity)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006906""(vesicle fusion)|go:""GO:0012505""(endomembrane system)|go:""GO:0019869""(chloride channel inhibitor activity)|go:""GO:0019905""(syntaxin binding)|go:""GO:0031201""(SNARE complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048278""(vesicle docking)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|interpro:IPR045242|mint:Q9UNK0|dip:DIP-47274N|panther:PTHR19957(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/05	rogid:jdsUOdy99aWRb94ndPtawff7z/o9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:2FE5BF171883DC7F|rigid:u6444GDsa+QowAErsoCTQLVHGww	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3A6	uniprotkb:Q5NEC5	intact:EBI-7560959|uniprotkb:D3DT38|intact:MINT-3085589|uniprotkb:B2R703|uniprotkb:Q96AX8|uniprotkb:B1AKT4|ensembl:ENSP00000359305.3	intact:EBI-22297545	psi-mi:tmed5_human(display_long)|uniprotkb:TMED5(gene name)|psi-mi:TMED5(display_short)|uniprotkb:p24 family protein gamma-2(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:CGI-100(orf name)|uniprotkb:UNQ397/PRO733(orf name)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299625|imex:IM-27563-329	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001161302.1|refseq:NP_057124.3|ensembl:ENSG00000117500.13(gene)|ensembl:ENST00000370282.8(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090161""(Golgi ribbon formation)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q9Y3A6|reactome:R-HSA-3238698|panther:PTHR22811(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	comment:mint|comment:homomint	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/02/27	rogid:3XAcqSucHNP4F3ilaBFRMSQ1B8Q9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:C30AF7D359473F26|rigid:q5tGmlp4Y+Jcb6KlJNIW6Ys7tzU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19320	uniprotkb:Q5NEC5	intact:EBI-6189824|uniprotkb:B4DKS4|uniprotkb:E9PDD1|uniprotkb:A8K6R7|uniprotkb:Q6NUP8|ensembl:ENSP00000294728.2	intact:EBI-22297545	psi-mi:vcam1_human(display_long)|uniprotkb:VCAM1(gene name)|psi-mi:VCAM1(display_short)|uniprotkb:INCAM-100(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299795|imex:IM-27563-63	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001069.1|refseq:NP_001186763.1|refseq:NP_542413.1|ensembl:ENSG00000162692.12(gene)|ensembl:ENST00000294728.7(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002102""(podosome)|go:""GO:0002544""(chronic inflammatory response)|go:""GO:0005178""(integrin binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007584""(response to nutrient)|go:""GO:0008131""(primary methylamine oxidase activity)|go:""GO:0009308""(amine metabolic process)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010043""(response to zinc ion)|go:""GO:0010212""(response to ionizing radiation)|go:""GO:0022614""(membrane to membrane docking)|go:""GO:0030175""(filopodium)|go:""GO:0030183""(B cell differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0033631""(cell-cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0035094""(response to nicotine)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042383""(sarcolemma)|go:""GO:0045177""(apical part of cell)|go:""GO:0045471""(response to ethanol)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0060384""(innervation)|go:""GO:0060945""(cardiac neuron differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071065""(alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0098631""(cell adhesion mediator activity)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR003989(Vascular cell adhesion molecule-1)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008424(Immunoglobulin C2-set)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR047012|mint:P19320|rcsb pdb:1IJ9|rcsb pdb:1VCA|rcsb pdb:1VSC|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-877300|panther:PTHR13771(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:ZgZa+cLeZ2PxFhdxPut2qd7QHVo9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:6DB17A71F960A634|rigid:ZBAcpUWSUd+Jtcv5BjwZR8+XMJ8	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15819	uniprotkb:Q5NEC5	intact:EBI-714329|ensembl:ENSP00000428209.1	intact:EBI-22297545	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299735|imex:IM-27563-425	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003341.1|ensembl:ENSG00000169139.12(gene)|ensembl:ENST00000523111.7(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000729""(DNA double-strand break processing)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006282""(regulation of DNA repair)|go:""GO:0006301""(postreplication repair)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031371""(ubiquitin conjugating enzyme complex)|go:""GO:0031372""(UBC13-MMS2 complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:1902523""(positive regulation of protein K63-linked ubiquitination)|go:""GO:2000781""(positive regulation of double-strand break repair)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:5AIT|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:8WR5|rcsb pdb:9BIV|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|dip:DIP-29830N|panther:PTHR24068(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/23	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:591908E77843CF5A|rigid:fLm9neeNRJ1KythKHoKh6JWTa6I	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14927	uniprotkb:Q5NFP9	intact:EBI-743128|uniprotkb:Q6FGD1|uniprotkb:E5RJU0|ensembl:ENSP00000287022.5	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:qcr7_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase complex 14 kDa protein(gene name synonym)|uniprotkb:Complex III subunit 7(gene name synonym)|uniprotkb:Complex III subunit VII(gene name synonym)|uniprotkb:QP-C(gene name synonym)|uniprotkb:UQCRB(gene name)|psi-mi:UQCRB(display_short)|uniprotkb:UQBP(gene name synonym)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299785|imex:IM-27563-171	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1460""|ensembl:ENSG00000156467.10(gene)|ensembl:ENST00000287022.10(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006122""(mitochondrial electron transport, ubiquinol to cytochrome c)|go:""GO:0009060""(aerobic respiration)|go:""GO:0045275""(respiratory chain complex III)|go:""GO:0045333""(cellular respiration)|go:""GO:0098803""(respiratory chain complex)|interpro:IPR003197(Cytochrome bd ubiquinol oxidase, 14 kDa subunit)|interpro:IPR036544|mint:P14927|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-9865881|refseq:NP_001186904.1|refseq:NP_001241681.1|refseq:NP_006285.1|panther:PTHR12022(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:JEa3rOlDB4nVyYDniZrcnF9b1Wg9606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:B49A873FD61D8359|rigid:9U+m4aGs2eWQoBPXisx2apmZtPU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60701	uniprotkb:Q5NGE3	intact:EBI-353006|uniprotkb:O60589|uniprotkb:B3KUU2|uniprotkb:B4DN25|ensembl:ENSP00000319501.6|ensembl:ENSP00000421757.1	intact:EBI-22297821|uniprotkb:A0A0G2RPC6	psi-mi:ugdh_human(display_long)|uniprotkb:UGDH(gene name)|psi-mi:UGDH(display_short)	psi-mi:q5nge3_fratt(display_long)|uniprotkb:FTT_0902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299775|imex:IM-27563-259	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001171629.1|refseq:NP_001171630.1|refseq:NP_003350.1|ensembl:ENSG00000109814.12(gene)|ensembl:ENST00000316423.11(transcript)|ensembl:ENST00000506179.5(transcript)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0003979""(UDP-glucose 6-dehydrogenase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006024""(glycosaminoglycan biosynthetic process)|go:""GO:0006065""(UDP-glucuronate biosynthetic process)|go:""GO:0015012""(heparan sulfate proteoglycan biosynthetic process)|go:""GO:0030206""(obsolete chondroitin sulfate biosynthetic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0042802""(identical protein binding)|go:""GO:0048666""(neuron development)|go:""GO:0051287""(NAD binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|mint:O60701|rcsb pdb:2Q3E|rcsb pdb:2QG4|rcsb pdb:3ITK|rcsb pdb:3KHU|rcsb pdb:3PRJ|rcsb pdb:3PTZ|rcsb pdb:3TDK|rcsb pdb:3TF5|rcsb pdb:4EDF|rcsb pdb:4RJT|rcsb pdb:5TJH|rcsb pdb:5VR8|rcsb pdb:5W4X|rcsb pdb:6C4J|rcsb pdb:6C4K|rcsb pdb:6C58|rcsb pdb:6C5A|rcsb pdb:6C5Z|reactome:R-HSA-173599|panther:PTHR11374(orthology-group)"	refseq:YP_169899.1|mint:Q5NGE3	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:FB1nDJFtfQk18OPze1TyR998SNk9606	rogid:NCB/Hok6C9lpbhvu2mMcLmSbgZs177416	intact-crc:4A7A38A53A9835CE|rigid:/7cskkINi3FYi/iFqQMLve/qwfY	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61960	uniprotkb:Q5NIG9	intact:EBI-1045061|uniprotkb:Q14346|uniprotkb:Q6IAG6|uniprotkb:Q9CPX2|uniprotkb:Q9NZF2|uniprotkb:Q5VXS0|ensembl:ENSP00000239878.4	intact:EBI-22299411|uniprotkb:A0A0G2RMS2	psi-mi:ufm1_human(display_long)|uniprotkb:UFM1(gene name)|psi-mi:UFM1(display_short)|uniprotkb:C13orf20(gene name synonym)|uniprotkb:BM-002(orf name)	psi-mi:q5nig9_fratt(display_long)|uniprotkb:FTT_0103c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299745|imex:IM-27563-331	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:139441""|ensembl:ENSG00000120686.12(gene)|ensembl:ENST00000239878.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007420""(brain development)|go:""GO:0033146""(regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0061709""(reticulophagy)|go:""GO:0071569""(protein ufmylation)|go:""GO:1990592""(protein K69-linked ufmylation)|interpro:IPR005375(Ubiquitin-like, Ufm1)|interpro:IPR029071|mint:P61960|rcsb pdb:1WXS|rcsb pdb:5HKH|rcsb pdb:5IA7|rcsb pdb:5IA8|rcsb pdb:5IAA|rcsb pdb:5L95|rcsb pdb:6H77|rcsb pdb:7W3N|rcsb pdb:8BZR|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8QFC|refseq:NP_001273632.1|refseq:NP_001273633.1|refseq:NP_001273634.1|refseq:NP_001273635.1|refseq:NP_057701.1|panther:PTHR15825(orthology-group)"	refseq:WP_003019536.1|refseq:YP_169173.1|interpro:IPR038721|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|mint:Q5NIG9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:zTJ0GOpHK6nPAOb6a93hQoAyNlE9606	rogid:TeoOWdARAaB8os8ExfibIgVqyp0177416	intact-crc:E8F77CEB658ABD95|rigid:9JMdxa8mw94fOWXUCWvL6dEtsdo	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43657	uniprotkb:Q5NEM9	intact:EBI-717435|uniprotkb:Q54A42|uniprotkb:Q6IAN9|ensembl:ENSP00000362111.4	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:tsn6_human(display_long)|uniprotkb:TSPAN6(gene name)|psi-mi:TSPAN6(display_short)|uniprotkb:TM4SF6(gene name synonym)|uniprotkb:Transmembrane 4 superfamily member 6(gene name synonym)|uniprotkb:T245 protein(gene name synonym)|uniprotkb:Tetraspanin TM4-D(gene name synonym)|uniprotkb:A15 homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 321(gene name synonym)|uniprotkb:UNQ767/PRO1560(orf name)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299715|imex:IM-27563-169	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003261.1|refseq:NP_001265672.1|ensembl:ENSG00000000003.16(gene)|ensembl:ENST00000373020.9(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0039532""(negative regulation of cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR048232|mint:O43657|panther:PTHR19282(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:mboW2aMSrqwnX5dgmVAtsrAQJqQ9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:EB78909EA54CB472|rigid:NPOpX5FKmvSrUy4Nqi7XpAUOp8Q	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61960	uniprotkb:Q5NEC5	intact:EBI-1045061|uniprotkb:Q14346|uniprotkb:Q6IAG6|uniprotkb:Q9CPX2|uniprotkb:Q9NZF2|uniprotkb:Q5VXS0|ensembl:ENSP00000239878.4	intact:EBI-22297545	psi-mi:ufm1_human(display_long)|uniprotkb:UFM1(gene name)|psi-mi:UFM1(display_short)|uniprotkb:C13orf20(gene name synonym)|uniprotkb:BM-002(orf name)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299765|imex:IM-27563-429	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:139441""|ensembl:ENSG00000120686.12(gene)|ensembl:ENST00000239878.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007420""(brain development)|go:""GO:0033146""(regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0061709""(reticulophagy)|go:""GO:0071569""(protein ufmylation)|go:""GO:1990592""(protein K69-linked ufmylation)|interpro:IPR005375(Ubiquitin-like, Ufm1)|interpro:IPR029071|mint:P61960|rcsb pdb:1WXS|rcsb pdb:5HKH|rcsb pdb:5IA7|rcsb pdb:5IA8|rcsb pdb:5IAA|rcsb pdb:5L95|rcsb pdb:6H77|rcsb pdb:7W3N|rcsb pdb:8BZR|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8QFC|refseq:NP_001273632.1|refseq:NP_001273633.1|refseq:NP_001273634.1|refseq:NP_001273635.1|refseq:NP_057701.1|panther:PTHR15825(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:zTJ0GOpHK6nPAOb6a93hQoAyNlE9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:BD52F2BEF693AC82|rigid:SPNY5Lle8WMqWEN0eFxqnsWa80Y	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15819	uniprotkb:Q5NHH2	intact:EBI-714329|ensembl:ENSP00000428209.1	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299725|imex:IM-27563-657	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003341.1|ensembl:ENSG00000169139.12(gene)|ensembl:ENST00000523111.7(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000729""(DNA double-strand break processing)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006282""(regulation of DNA repair)|go:""GO:0006301""(postreplication repair)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031371""(ubiquitin conjugating enzyme complex)|go:""GO:0031372""(UBC13-MMS2 complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:1902523""(positive regulation of protein K63-linked ubiquitination)|go:""GO:2000781""(positive regulation of double-strand break repair)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:5AIT|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:8WR5|rcsb pdb:9BIV|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|dip:DIP-29830N|panther:PTHR24068(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/23	rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:918C4FFC7F34C966|rigid:9m8STWDnepASerzR/zo6p12UIIE	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61960	uniprotkb:Q5NEV0	intact:EBI-1045061|uniprotkb:Q14346|uniprotkb:Q6IAG6|uniprotkb:Q9CPX2|uniprotkb:Q9NZF2|uniprotkb:Q5VXS0|ensembl:ENSP00000239878.4	intact:EBI-22299174|uniprotkb:A0A0G2RP53	psi-mi:ufm1_human(display_long)|uniprotkb:UFM1(gene name)|psi-mi:UFM1(display_short)|uniprotkb:C13orf20(gene name synonym)|uniprotkb:BM-002(orf name)	"psi-mi:q5nev0_fratt(display_long)|uniprotkb:relA(gene name)|psi-mi:relA(display_short)|uniprotkb:""(p)ppGpp synthase""(gene name synonym)|uniprotkb:""ATP:GTP 3'-pyrophosphotransferase""(gene name synonym)|uniprotkb:ppGpp synthase I(gene name synonym)|uniprotkb:FTT_1508c(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299755|imex:IM-27563-427	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:139441""|ensembl:ENSG00000120686.12(gene)|ensembl:ENST00000239878.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007420""(brain development)|go:""GO:0033146""(regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0061709""(reticulophagy)|go:""GO:0071569""(protein ufmylation)|go:""GO:1990592""(protein K69-linked ufmylation)|interpro:IPR005375(Ubiquitin-like, Ufm1)|interpro:IPR029071|mint:P61960|rcsb pdb:1WXS|rcsb pdb:5HKH|rcsb pdb:5IA7|rcsb pdb:5IA8|rcsb pdb:5IAA|rcsb pdb:5L95|rcsb pdb:6H77|rcsb pdb:7W3N|rcsb pdb:8BZR|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8QFC|refseq:NP_001273632.1|refseq:NP_001273633.1|refseq:NP_001273634.1|refseq:NP_001273635.1|refseq:NP_057701.1|panther:PTHR15825(orthology-group)"	"go:""GO:0005525""(GTP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0008728""(GTP diphosphokinase activity)|go:""GO:0008893""(""guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"")|go:""GO:0015969""(guanosine tetraphosphate metabolic process)|go:""GO:0016301""(kinase activity)|go:""GO:0042594""(response to starvation)|refseq:WP_003025932.1|refseq:YP_170442.1|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004811(RelA/SpoT protein)|interpro:IPR007685(RelA/SpoT)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|interpro:IPR033655|mint:Q5NEV0|interpro:IPR043519"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:zTJ0GOpHK6nPAOb6a93hQoAyNlE9606	rogid:j8MreXRGyjWTWSOsZagqQx0cTxU177416	intact-crc:DD2E0B99322BA5FC|rigid:d9OxsqEhlDO9USoAbblu29g5lCU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08AN1	uniprotkb:Q5NFP9	intact:EBI-11017730|uniprotkb:Q658V7|uniprotkb:B3KRV1|uniprotkb:Q0P658|ensembl:ENSP00000471000.1	intact:EBI-2797731|uniprotkb:A0A0G2RNB4	psi-mi:zn616_human(display_long)|uniprotkb:ZNF616(gene name)|psi-mi:ZNF616(display_short)	psi-mi:q5nfp9_fratt(display_long)|uniprotkb:bipA(gene name)|psi-mi:bipA(display_short)|uniprotkb:GTP-binding protein BipA(gene name synonym)|uniprotkb:FTT_1179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299925|imex:IM-27563-591	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_848618.2|ensembl:ENSG00000204611.7(gene)|ensembl:ENST00000600228.6(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR050329|mint:Q08AN1|reactome:R-HSA-212436|panther:PTHR24377(orthology-group)"	"go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000049""(tRNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019843""(rRNA binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0097216""(guanosine tetraphosphate binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR006298(GTP-binding protein TypA)|refseq:YP_170143.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR027417|interpro:IPR031157|refseq:WP_003021411.1|mint:Q5NFP9|interpro:IPR035647|interpro:IPR035651|interpro:IPR042116|interpro:IPR048876|interpro:IPR047041|interpro:IPR047042|interpro:IPR047043"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:w9RDDdjfFGbD7posXDXkYJ0A7p09606	rogid:IMFVT+yg6AiYrK3dkpu3rb/VnqE177416	intact-crc:D73E94BBE3C670FF|rigid:p5AACHMaAEsfUbsHxAflRkoVpZI	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q969J2	uniprotkb:Q5NHT8	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|ensembl:ENSP00000366509.2|intact:EBI-28979011	intact:EBI-2806309	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:htpg_fratt(display_long)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:FTT_0356(locus name)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:Heat shock protein HtpG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299905|imex:IM-27563-663	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_061983.2|refseq:XP_005249152.1|ensembl:ENSG00000187626.9(gene)|ensembl:ENST00000377294.3(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|panther:PTHR23226(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:YP_169404.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR036890|interpro:IPR037196|mint:Q5NHT8|refseq:WP_003020060.1"	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rogid:OWLagz5qozUwhWkHC9U9vSpB/fw177416	intact-crc:44FFE8EDC2374F9A|rigid:bLKF1NUCCGDmLIqp32WMh/qIT2Q	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P45880	uniprotkb:Q5NEC5	intact:EBI-354022|uniprotkb:Q5VWK1|uniprotkb:Q5VWK3|uniprotkb:Q6IB40|uniprotkb:Q7L3J5|uniprotkb:Q9BWK8|uniprotkb:Q9Y5I6|ensembl:ENSP00000361686.3|ensembl:ENSP00000443092.1	intact:EBI-22297545	psi-mi:vdac2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299815|imex:IM-27563-431	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001171712.1|refseq:NP_001171752.1|refseq:NP_003366.2|ensembl:ENSG00000165637.14(gene)|ensembl:ENST00000332211.11(transcript)|ensembl:ENST00000543351.5(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005244""(voltage-gated monoatomic ion channel activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006820""(monoatomic anion transport)|go:""GO:0007339""(binding of sperm to zona pellucida)|go:""GO:0008142""(oxysterol binding)|go:""GO:0008308""(voltage-gated monoatomic anion channel activity)|go:""GO:0015288""(porin activity)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032272""(negative regulation of protein polymerization)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0045121""(membrane raft)|go:""GO:0045332""(phospholipid translocation)|go:""GO:0046930""(pore complex)|go:""GO:0097001""(ceramide binding)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097345""(mitochondrial outer membrane permeabilization)|go:""GO:1990542""(mitochondrial transmembrane transport)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|mint:P45880|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-8949215|refseq:NP_001311017.1|panther:PTHR11743(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:seQxCd19Z2HmpXcwb48osAuuafA9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:3D459B3BA5B56714|rigid:togWSw0Vjw0g2R5azr5i5ie8uwE	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y4E5	uniprotkb:Q5NEC5	intact:EBI-747230|uniprotkb:Q5VVF1|uniprotkb:Q8N380|uniprotkb:Q8TD15|uniprotkb:Q9NQM1|uniprotkb:Q86YE4|uniprotkb:Q9C0G1|ensembl:ENSP00000359740.4|intact:EBI-1104831|uniprotkb:Q5VVE9	intact:EBI-22297545	psi-mi:zn451_human(display_long)|uniprotkb:KIAA1702(gene name synonym)|uniprotkb:Coactivator for steroid receptors(gene name synonym)|uniprotkb:ZNF451(gene name)|psi-mi:ZNF451(display_short)|uniprotkb:COASTER(gene name synonym)|uniprotkb:KIAA0576(gene name synonym)|uniprotkb:Zinc finger protein 451(gene name synonym)|uniprotkb:E3 SUMO-protein transferase ZNF451(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299915|imex:IM-27563-589	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001026794.1|refseq:NP_056370.2|ensembl:ENSG00000112200.17(gene)|ensembl:ENST00000370706.9(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0016605""(PML body)|go:""GO:0016925""(protein sumoylation)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0060633""(negative regulation of transcription initiation by RNA polymerase II)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0140416""(transcription regulator inhibitor activity)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041192|mint:Q9Y4E5|rcsb pdb:5D2M|dip:DIP-51264N|panther:PTHR24408(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:WNBXLe+XYJ7nSNhgXZL3keG5OYo9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:BFA6CF0B2A779521|rigid:aJV9EOwnuCSrhKBGj8fdzy6Z7no	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P23025	uniprotkb:Q5NHH2	intact:EBI-295222|uniprotkb:Q6LCW7|uniprotkb:Q5T1U9|uniprotkb:Q6LD02|ensembl:ENSP00000364270.5	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:xpa_human(display_long)|uniprotkb:XPA(gene name)|psi-mi:XPA(display_short)|uniprotkb:XPAC(gene name synonym)|uniprotkb:Xeroderma pigmentosum group A-complementing protein(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299855|imex:IM-27563-433	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136936.11(gene)|ensembl:ENST00000375128.5(transcript)|go:""GO:0000110""(nucleotide-excision repair factor 1 complex)|go:""GO:0000715""(nucleotide-excision repair, DNA damage recognition)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0006284""(base-excision repair)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0009650""(UV protection)|go:""GO:0010996""(response to auditory stimulus)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045171""(intercellular bridge)|go:""GO:0046872""(metal ion binding)|go:""GO:0070914""(UV-damage excision repair)|go:""GO:1901255""(nucleotide-excision repair involved in interstrand cross-link repair)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000465(XPA)|interpro:IPR009061(Putative DNA binding)|interpro:IPR022652|interpro:IPR022656|interpro:IPR022658|interpro:IPR037129|mint:P23025|rcsb pdb:1D4U|rcsb pdb:1XPA|rcsb pdb:2JNW|rcsb pdb:6J44|rcsb pdb:6LAE|rcsb pdb:6RO4|rcsb pdb:7AD8|rcsb pdb:8EBT|rcsb pdb:8EBU|rcsb pdb:8EBX|rcsb pdb:8EBY|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6782135|refseq:NP_000371.1|dip:DIP-24191N|efo:""Orphanet:910""|panther:PTHR10142(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/27	rogid:pHnq8HVW+SweFUtxsfwUaQcRokE9606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:BD7821CA282C195C|rigid:i25ga21R6TH2imetkxPyMXVjL4I	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75152	uniprotkb:Q5NGE3	intact:EBI-748480|uniprotkb:Q6AHY4|uniprotkb:Q6AHY9|uniprotkb:Q6AW79|uniprotkb:Q6AWA1|uniprotkb:Q6PJK4|uniprotkb:Q86XZ7|ensembl:ENSP00000333253.4|ensembl:ENSP00000356179.1|ensembl:ENSP00000356181.3|ensembl:ENSP00000356183.1|ensembl:ENSP00000491830.1	intact:EBI-22297821|uniprotkb:A0A0G2RPC6	psi-mi:zc11a_human(display_long)|uniprotkb:ZC3H11A(gene name)|psi-mi:ZC3H11A(display_short)|uniprotkb:KIAA0663(gene name synonym)|uniprotkb:ZC3HDC11A(gene name synonym)	psi-mi:q5nge3_fratt(display_long)|uniprotkb:FTT_0902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299895|imex:IM-27563-173	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_006711736.1|refseq:NP_055642.3|refseq:XP_011508501.1|refseq:XP_011508502.1|refseq:XP_011508503.1|refseq:XP_011508504.1|ensembl:ENSG00000058673.17(gene)|ensembl:ENST00000332127.8(transcript)|ensembl:ENST00000367210.3(transcript)|ensembl:ENST00000367212.7(transcript)|ensembl:ENST00000367214.5(transcript)|ensembl:ENST00000639812.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR041686|mint:O75152|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_001306167.1|refseq:NP_001306168.1|refseq:XP_005245700.1|refseq:XP_005245701.1|refseq:XP_016858445.1|refseq:XP_016858446.1|refseq:XP_016858447.1|refseq:XP_016858448.1|panther:PTHR15725(orthology-group)"	refseq:YP_169899.1|mint:Q5NGE3	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:BJfX/K7kBXQGQx6l+Y2xBtwyJAw9606	rogid:NCB/Hok6C9lpbhvu2mMcLmSbgZs177416	intact-crc:8E831C341792ECD9|rigid:ioYz/dwmuv+YrwicprcRfBpU9+s	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P23025	uniprotkb:Q5NEC5	intact:EBI-295222|uniprotkb:Q6LCW7|uniprotkb:Q5T1U9|uniprotkb:Q6LD02|ensembl:ENSP00000364270.5	intact:EBI-22297545	psi-mi:xpa_human(display_long)|uniprotkb:XPA(gene name)|psi-mi:XPA(display_short)|uniprotkb:XPAC(gene name synonym)|uniprotkb:Xeroderma pigmentosum group A-complementing protein(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299845|imex:IM-27563-67	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136936.11(gene)|ensembl:ENST00000375128.5(transcript)|go:""GO:0000110""(nucleotide-excision repair factor 1 complex)|go:""GO:0000715""(nucleotide-excision repair, DNA damage recognition)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0006284""(base-excision repair)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0009650""(UV protection)|go:""GO:0010996""(response to auditory stimulus)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045171""(intercellular bridge)|go:""GO:0046872""(metal ion binding)|go:""GO:0070914""(UV-damage excision repair)|go:""GO:1901255""(nucleotide-excision repair involved in interstrand cross-link repair)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000465(XPA)|interpro:IPR009061(Putative DNA binding)|interpro:IPR022652|interpro:IPR022656|interpro:IPR022658|interpro:IPR037129|mint:P23025|rcsb pdb:1D4U|rcsb pdb:1XPA|rcsb pdb:2JNW|rcsb pdb:6J44|rcsb pdb:6LAE|rcsb pdb:6RO4|rcsb pdb:7AD8|rcsb pdb:8EBT|rcsb pdb:8EBU|rcsb pdb:8EBX|rcsb pdb:8EBY|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6782135|refseq:NP_000371.1|dip:DIP-24191N|efo:""Orphanet:910""|panther:PTHR10142(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/01/27	rogid:pHnq8HVW+SweFUtxsfwUaQcRokE9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:75ED66D12F5B1F60|rigid:LuqoV4wF4KsmgMzw+CoRCAusuCE	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NAP3	uniprotkb:Q5NEC5	intact:EBI-5235984|uniprotkb:D3DNF6|ensembl:ENSP00000372635.5|ensembl:ENSP00000406955.2|ensembl:ENSP00000426387.1|ensembl:ENSP00000490041.1|intact:EBI-28968990	intact:EBI-22297545	psi-mi:zbt38_human(display_long)|uniprotkb:ZBTB38(gene name)|psi-mi:ZBTB38(display_short)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299875|imex:IM-27563-661	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011510913.1|refseq:XP_005247314.1|refseq:XP_005247315.1|refseq:NP_001073881.2|ensembl:ENSG00000177311.12(gene)|ensembl:ENST00000321464.7(transcript)|ensembl:ENST00000441582.2(transcript)|ensembl:ENST00000514251.5(transcript)|ensembl:ENST00000637056.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006974""(DNA damage response)|go:""GO:0008327""(methyl-CpG binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0072562""(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8NAP3|rcsb pdb:6E93|rcsb pdb:6E94|refseq:XP_005247318.1|refseq:XP_016861550.1|refseq:XP_016861541.1|refseq:XP_016861542.1|refseq:XP_016861543.1|refseq:XP_016861544.1|refseq:XP_016861545.1|refseq:XP_016861546.1|refseq:XP_016861547.1|refseq:XP_016861548.1|refseq:XP_016861549.1|panther:PTHR24388(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:2hYBmm9S5uBZPL4JBUvGWQaTPak9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:73E96A664527AF9C|rigid:W5AdGj6GZ/WfmP+6ACgi9L88NTk	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NCP5	uniprotkb:Q5NES6	intact:EBI-5658292|uniprotkb:Q86VJ7|uniprotkb:Q6IPT8|uniprotkb:Q86XX5|intact:EBI-28972467	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:zbt44_human(display_long)|uniprotkb:BTB/POZ domain-containing protein 15(gene name synonym)|uniprotkb:BTBD15(gene name synonym)|uniprotkb:ZNF851(gene name synonym)|uniprotkb:Zinc finger protein 851(gene name synonym)|uniprotkb:ZBTB44(gene name)|psi-mi:ZBTB44(display_short)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299885|imex:IM-27563-69	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q8NCP5|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_054874.3|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0046872""(metal ion binding)|refseq:NP_001288027.1|refseq:NP_001288028.1|interpro:IPR036236|refseq:XP_016873112.1|panther:PTHR24383(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:xewgUIEkS1YVch+LlFi+bSwFZ2Y9606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:6B18718ED2D71F7B|rigid:faScAGpN4xY2Y6Aibci+/QlBET4	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96TA2	uniprotkb:Q5NES6	intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV9|uniprotkb:D3DRV8|uniprotkb:B4DNM1|ensembl:ENSP00000318480.3|intact:EBI-10989776	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299865|imex:IM-27563-659	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136758.21(gene)|ensembl:ENST00000326799.7(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010636""(positive regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034214""(protein hexamerization)|go:""GO:0034982""(mitochondrial protein processing)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664|reactome:R-HSA-9837999|reactome:R-HSA-9840373|refseq:NP_001240795.1|refseq:NP_055078.1|refseq:NP_647473.1|efo:""Orphanet:98676""|panther:PTHR23076(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:DFEDFCE21B4C3B20|rigid:bLGde4w0/CJkWwewtwEFNHeJVAQ	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TAF3	uniprotkb:Q5NES6	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491.5	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299835|imex:IM-27563-65	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50841N|efo:""Orphanet:401800""|ensembl:ENSG00000114742.14(gene)|ensembl:ENST00000302313.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043588""(skin development)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:1902525""(regulation of protein monoubiquitination)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|interpro:IPR051246|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|refseq:NP_065890.1|panther:PTHR19862(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:28CEA8705146F693|rigid:UzkaPlL7cM54WCkL2NHTBKUQi1g	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TAF3	uniprotkb:Q5NHH2	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491.5	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299825|imex:IM-27563-335	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50841N|efo:""Orphanet:401800""|ensembl:ENSG00000114742.14(gene)|ensembl:ENST00000302313.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043588""(skin development)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:1902525""(regulation of protein monoubiquitination)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|interpro:IPR051246|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|refseq:NP_065890.1|panther:PTHR19862(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:EA64DE390053E0BB|rigid:agUtX1tlZcgMfuuLfP3fqheTpms	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96JH7	uniprotkb:Q5NEC5	intact:EBI-1995920|ensembl:ENSP00000309031.4|uniprotkb:Q504T4|uniprotkb:Q86T93|uniprotkb:Q86W01|uniprotkb:Q8N3A9|uniprotkb:Q9H5R8	intact:EBI-22297545	psi-mi:vcip1_human(display_long)|uniprotkb:VCPIP1(gene name)|psi-mi:VCPIP1(display_short)|uniprotkb:KIAA1850(gene name synonym)|uniprotkb:VCIP135(gene name synonym)|uniprotkb:Valosin-containing protein p97/p47 complex-interacting protein p135(gene name synonym)|uniprotkb:Valosin-containing protein p97/p47 complex-interacting protein 1(gene name synonym)	psi-mi:q5nec5_fratt(display_long)|uniprotkb:iglC2(gene name)|psi-mi:iglC2(display_short)|uniprotkb:iglC1(gene name synonym)|uniprotkb:FTT_1357c(locus name)|uniprotkb:FTT_1712c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22299805|imex:IM-27563-333	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079330.2|ensembl:ENSG00000175073.8(gene)|ensembl:ENST00000310421.5(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005795""(Golgi stack)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016320""(endoplasmic reticulum membrane fusion)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0035871""(protein K11-linked deubiquitination)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:0090168""(Golgi reassembly)|go:""GO:0106300""(protein-DNA covalent cross-linking repair)|go:""GO:1905634""(regulation of protein localization to chromatin)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR029071|interpro:IPR039087|interpro:IPR045827|interpro:IPR048857|mint:Q96JH7|rcsb pdb:8YKA|reactome:R-HSA-5689896|panther:PTHR14843(orthology-group)"	rcsb pdb:2QWU|refseq:YP_170309.1|refseq:YP_170617.1|interpro:IPR021048|mint:Q5NEC5	-	-	-	figure legend:ST2 F1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:EMqKXIMqv42Vlg5oUS+kT9WI5BQ9606	rogid:845AInuImIbj1XfNf0c+Vx3g2/E177416	intact-crc:97DF2D9F66933258|rigid:F8zuTcDNCTU1/EBU8svRXZkNWfw	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11021	uniprotkb:Q5NES6	intact:EBI-354921|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61|ensembl:ENSP00000324173.6	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22301978|imex:IM-27563-217	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005338.1|ensembl:ENSG00000044574.9(gene)|ensembl:ENST00000324460.7(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006983""(ER overload response)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021589""(cerebellum structural organization)|go:""GO:0021680""(cerebellar Purkinje cell layer development)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030291""(protein serine/threonine kinase inhibitor activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031204""(post-translational protein targeting to membrane, translocation)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035437""(maintenance of protein localization in endoplasmic reticulum)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042026""(protein refolding)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042470""(melanosome)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060904""(regulation of protein folding in endoplasmic reticulum)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071353""(cellular response to interleukin-4)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1903891""(regulation of ATF6-mediated unfolded protein response)|go:""GO:1903894""(regulation of IRE1-mediated unfolded protein response)|go:""GO:1903895""(negative regulation of IRE1-mediated unfolded protein response)|go:""GO:1903897""(regulation of PERK-mediated unfolded protein response)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|rcsb pdb:7N1R|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-8874177|reactome:R-HSA-983170|dip:DIP-33189N|panther:PTHR19375(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2025/03/25	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:D1335C9955EE634D|rigid:ijGbSaLCem4vq76DKLWO3FJrADA	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y2T2	uniprotkb:Q5NES6	intact:EBI-2371151|uniprotkb:Q5JQ12|uniprotkb:Q9H5L2|ensembl:ENSP00000347408.4|ensembl:ENSP00000361831.1	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:ap3m1_human(display_long)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu-1(gene name synonym)|uniprotkb:AP3M1(gene name)|psi-mi:AP3M1(display_short)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:Mu3A-adaptin(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22301998|imex:IM-27563-557	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001307192.1|refseq:NP_001307193.1|ensembl:ENSG00000185009.13(gene)|ensembl:ENST00000355264.9(transcript)|ensembl:ENST00000372745.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030131""(clathrin adaptor complex)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0046907""(intracellular transport)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0098837""(postsynaptic recycling endosome)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR050431|mint:Q9Y2T2|reactome:R-HSA-390471|refseq:NP_036227.1|refseq:NP_996895.1|panther:PTHR10529(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:VsXYkOxEite1RzT1YHCA6/U4gj09606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:3EB600B7E9B5935B|rigid:0/1nLmr+rCZ0nK5ABE7snVBEB9Y	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q9Y2T2	uniprotkb:Q5NEM9	intact:EBI-2371151|uniprotkb:Q5JQ12|uniprotkb:Q9H5L2|ensembl:ENSP00000347408.4|ensembl:ENSP00000361831.1	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:ap3m1_human(display_long)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu-1(gene name synonym)|uniprotkb:AP3M1(gene name)|psi-mi:AP3M1(display_short)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:Mu3A-adaptin(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302008|imex:IM-27563-219	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001307192.1|refseq:NP_001307193.1|ensembl:ENSG00000185009.13(gene)|ensembl:ENST00000355264.9(transcript)|ensembl:ENST00000372745.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030131""(clathrin adaptor complex)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0046907""(intracellular transport)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0098837""(postsynaptic recycling endosome)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR050431|mint:Q9Y2T2|reactome:R-HSA-390471|refseq:NP_036227.1|refseq:NP_996895.1|panther:PTHR10529(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:VsXYkOxEite1RzT1YHCA6/U4gj09606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:10DFE62983279C0A|rigid:0UlfXPFaATOt/KCTZVC8cp7TThs	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q96PU8	uniprotkb:Q5NEM9	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094.3	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)|uniprotkb:Protein quaking(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302028|imex:IM-27563-119	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000112531.17(gene)|ensembl:ENST00000361752.8(transcript)|go:""GO:0001570""(vasculogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007286""(spermatid development)|go:""GO:0008298""(intracellular mRNA localization)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010717""(regulation of epithelial to mesenchymal transition)|go:""GO:0014004""(microglia differentiation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031643""(positive regulation of myelination)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0035198""(miRNA binding)|go:""GO:0035886""(vascular associated smooth muscle cell differentiation)|go:""GO:0042552""(myelination)|go:""GO:0042759""(long-chain fatty acid biosynthetic process)|go:""GO:0045202""(synapse)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045649""(regulation of macrophage differentiation)|go:""GO:0045650""(negative regulation of macrophage differentiation)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0048710""(regulation of astrocyte differentiation)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0051028""(mRNA transport)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0160089""(""internal N(7)-methylguanine-containing RNA reader activity"")|go:""GO:0160091""(spliceosome-depend formation of circular RNA)|go:""GO:1905869""(negative regulation of 3'-UTR-mediated mRNA stabilization)|go:""GO:1990764""(myofibroblast contraction)|go:""GO:2000626""(negative regulation of miRNA catabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|interpro:IPR045071|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952|refseq:NP_001288014.1|refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:XP_011534561.1|efo:""Orphanet:251671""|ensembl:ENST00000275262.11|ensembl:ENSP00000275262.7|ensembl:ENST00000361195.6|ensembl:ENSP00000354867.2|ensembl:ENSP00000355094.3|ensembl:ENST00000361758.8|ensembl:ENSP00000354951.4|ensembl:ENST00000392127.6|ensembl:ENSP00000375973.2|ensembl:ENST00000424802.7|ensembl:ENSP00000408382.3|ensembl:ENST00000453779.6|ensembl:ENSP00000408775.2|panther:PTHR11208(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:0F1A3EF24CA55DEE|rigid:nhzpYDIgd2X9IHxihsDYUNHtFZU	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TAF3	uniprotkb:Q5NHH2	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491.5	intact:EBI-2800302|uniprotkb:A0A0G2RQ19	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	psi-mi:q5nhh2_fratt(display_long)|uniprotkb:FTT_0482c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22301968|imex:IM-27563-539	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50841N|efo:""Orphanet:401800""|ensembl:ENSG00000114742.14(gene)|ensembl:ENST00000302313.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043588""(skin development)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:1902525""(regulation of protein monoubiquitination)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|interpro:IPR051246|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|refseq:NP_065890.1|panther:PTHR19862(orthology-group)"	refseq:YP_169520.1|interpro:IPR021699|refseq:WP_003020291.1|mint:Q5NHH2	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	rogid:bm6LocX/Viuy004nc3Q0SGNq/f0177416	intact-crc:D8ECA901B7CBC4CB|rigid:agUtX1tlZcgMfuuLfP3fqheTpms	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TAF3	uniprotkb:Q5NES6	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491.5	intact:EBI-2797864|uniprotkb:A0A0G2RPR2	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	psi-mi:q5nes6_fratt(display_long)|uniprotkb:FTT_1538c(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22301988|imex:IM-27563-479	intact-miscore:0.49	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50841N|efo:""Orphanet:401800""|ensembl:ENSG00000114742.14(gene)|ensembl:ENST00000302313.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043588""(skin development)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:1902525""(regulation of protein monoubiquitination)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|interpro:IPR051246|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|refseq:NP_065890.1|panther:PTHR19862(orthology-group)"	refseq:YP_170466.1|refseq:WP_003022423.1|mint:Q5NES6|interpro:IPR014094(Uncharacterized conserved lipoprotein, UCP02722)	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	rogid:uCau2WgCxk4uc+Rm/AOn6xZRRMg177416	intact-crc:5A0DB42357A3A04D|rigid:UzkaPlL7cM54WCkL2NHTBKUQi1g	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q8TAF3	uniprotkb:Q5NEM9	intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491.5	intact:EBI-2799236|uniprotkb:A0A0G2RPP0	psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym)	psi-mi:q5nem9_fratt(display_long)|uniprotkb:FTT_1597(locus name)	"psi-mi:""MI:0397""(two hybrid array)"	Wallqvist et al. (2014)	pubmed:26714771|doi:10.1186/s12864-015-2351-1|imex:IM-27563	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:177416(fratt)|taxid:177416(Francisella tularensis subsp. tularensis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22302018|imex:IM-27563-559	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50841N|efo:""Orphanet:401800""|ensembl:ENSG00000114742.14(gene)|ensembl:ENST00000302313.10(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043588""(skin development)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048568""(embryonic organ development)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:1902525""(regulation of protein monoubiquitination)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|interpro:IPR051246|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|rcsb pdb:8A9J|rcsb pdb:8A9K|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|refseq:NP_065890.1|panther:PTHR19862(orthology-group)"	refseq:YP_170513.1|refseq:WP_003022515.1|mint:Q5NEM9	-	-	-	figure legend:ST5|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2019/11/14	2024/11/14	rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606	rogid:AHHZc/gDrcd8riKRjTLIVZy6nb8177416	intact-crc:746452BD3D31AF1C|rigid:CJ69eYvAEWtogpKkWlbKJ+v7Iek	false	tag:c-c	tag:n-n	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:A8DS70	uniprotkb:Q86X29	intact:EBI-25634990	intact:EBI-1056946|uniprotkb:O00112|uniprotkb:O00426|uniprotkb:Q6ZT80|uniprotkb:Q9UQL3|uniprotkb:E9PHD4|uniprotkb:Q8NBM0|uniprotkb:Q9BT33|uniprotkb:A6NDW3|ensembl:ENSP00000480821.1|intact:EBI-10982122|uniprotkb:B4DKL4	psi-mi:a8ds70_clodi(display_long)|uniprotkb:cdtB(gene name)|psi-mi:cdtB(display_short)	psi-mi:lsr_human(display_long)|uniprotkb:Angulin-1(gene name synonym)|uniprotkb:ILDR3(gene name synonym)|uniprotkb:LSR(gene name)|psi-mi:LSR(display_short)|uniprotkb:LISCH(gene name synonym)	"psi-mi:""MI:0969""(bio-layer interferometry)"	Anderson et al. (2019)	pubmed:31712627|imex:IM-28296	taxid:1496(clodi)|taxid:1496(Clostridium difficile)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0465""(DIP)"	intact:EBI-25635051|imex:IM-28296-5	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:8DCM|rcsb pdb:8DCN|rcsb pdb:7VNJ|rcsb pdb:7VNN|rcsb pdb:7YVQ|rcsb pdb:7YVS|refseq:WP_009890823.1|rcsb pdb:6O2M|rcsb pdb:6O2N|rcsb pdb:6O2O|rcsb pdb:6OKR|rcsb pdb:6OKS|rcsb pdb:6OKT|rcsb pdb:6OKU|interpro:IPR003896(Bacterial exotoxin B)|go:""GO:0005576""(extracellular region)|go:""GO:0016740""(transferase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051260""(protein homooligomerization)|interpro:IPR035331|interpro:IPR011658(PA14)|interpro:IPR035088|interpro:IPR027439|interpro:IPR037149|rcsb pdb:6V1S"	"refseq:NP_991403.1|refseq:NP_001247418.1|refseq:NP_001247419.1|refseq:NP_057009.3|refseq:NP_991404.1|ensembl:ENSG00000105699.17(gene)|ensembl:ENST00000621372.4(transcript)|go:""GO:0001889""(liver development)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0030054""(cell junction)|go:""GO:0034361""(very-low-density lipoprotein particle)|go:""GO:0034362""(low-density lipoprotein particle)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042627""(chylomicron)|go:""GO:0060856""(establishment of blood-brain barrier)|go:""GO:0061436""(establishment of skin barrier)|go:""GO:0061689""(tricellular tight junction)|go:""GO:0061833""(protein localization to tricellular tight junction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070160""(tight junction)|go:""GO:1904274""(tricellular tight junction assembly)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008664(LISCH7)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR051874|mint:Q86X29|reactome:R-HSA-8964038|reactome:R-HSA-8964046|panther:PTHR15923(orthology-group)"	-	-	-	figure legend:ExtFig6c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/11/19	2024/11/14	rogid:AImIjZm3u9ukW3Su4C0549I5kUw1496	rogid:jCmNdVxzNBHEpWjKNqyq5e6yEjs9606	intact-crc:061A22C9E6D5337B|rigid:IyCa5TuKGwMw4YKPXkWEdqFVdmw	false	binding-associated region:43-876	his tag:c-c|binding-associated region:1-259	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:B7UM99	uniprotkb:P05783	intact:EBI-2504426|uniprotkb:O50190|uniprotkb:O52147	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487.3|ensembl:ENSP00000373489.2	psi-mi:tir_eco27(display_long)|uniprotkb:tir(gene name)|psi-mi:tir(display_short)|uniprotkb:Secreted effector protein Tir(gene name synonym)|uniprotkb:espE(gene name synonym)|uniprotkb:E2348C_3941(locus name)	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Batchelor et al. (2004)	imex:IM-27518|pubmed:14710194	"taxid:574521(eco27)|taxid:574521(""Escherichia coli O127:H6 (strain E2348/69 / EPEC)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-22228314|imex:IM-27518-1	intact-miscore:0.66	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:B7UM99|refseq:WP_001339882.1|dip:DIP-27648N|dip:DIP-55921N|go:""GO:0005576""(extracellular region)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042169""(SH2 domain binding)|interpro:IPR003536(Translocated intimin receptor)|interpro:IPR022633|interpro:IPR022638|interpro:IPR022639|interpro:IPR037003|rcsb pdb:2CI9|rcsb pdb:2CIA|rcsb pdb:5WEZ"	"refseq:NP_000215.1|refseq:NP_954657.1|ensembl:ENSG00000111057.11(gene)|ensembl:ENST00000388835.4(transcript)|ensembl:ENST00000388837.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005912""(adherens junction)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0016363""(nuclear matrix)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045095""(keratin filament)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-633N|panther:PTHR23239(orthology-group)"	-	-	-	figure legend:fig 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/11/25	2025/03/25	rogid:KzZZf57ln3nXEZ0Rpn9Tf/B1DCk574521	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	intact-crc:E6F07334B2D00536|rigid:VfXrurNnW99L71cDN2oN/BJy/Vw	false	mutation increasing interaction rate:474-474	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P9WHW9	uniprotkb:O60603	intact:EBI-9086224|uniprotkb:L0TFI2|uniprotkb:Q7D4P4|uniprotkb:Q79F92	intact:EBI-973722|uniprotkb:O15454|uniprotkb:Q8NI00|ensembl:ENSP00000260010.6|ensembl:ENSP00000493968.2|ensembl:ENSP00000494425.1|ensembl:ENSP00000495339.1|ensembl:ENSP00000496208.2|ensembl:ENSP00000496676.2|ensembl:ENSP00000519700.1|ensembl:ENSP00000519701.1|ensembl:ENSP00000519702.1|ensembl:ENSP00000519703.1|ensembl:ENSP00000519704.1|uniprotkb:B3Y612|uniprotkb:D1CS45|uniprotkb:D1CS48|uniprotkb:D1CS49	psi-mi:ppe68_myctu(display_long)|uniprotkb:PPE68(gene name)|psi-mi:PPE68(display_short)|uniprotkb:Rv3873(locus name)	psi-mi:tlr2_human(display_long)|uniprotkb:Toll/interleukin-1 receptor-like protein 4(gene name synonym)|uniprotkb:TLR2(gene name)|psi-mi:TLR2(display_short)|uniprotkb:TIL4(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Tiwari et al. (2014)	pubmed:24467650|imex:IM-22080	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9086355|imex:IM-22080-4	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0052572""(response to host immune response)|interpro:IPR000030(Mycobacterial PPE protein)|refseq:YP_178022.1|refseq:WP_003399879.1|interpro:IPR038332|mint:P9WHW9"	"ensembl:ENSG00000137462.10(gene)|ensembl:ENST00000260010.7(transcript)|ensembl:ENST00000642580.1(transcript)|ensembl:ENST00000642700.2(transcript)|ensembl:ENST00000643501.2(transcript)|ensembl:ENST00000646219.2(transcript)|ensembl:ENST00000646900.2(transcript)|ensembl:ENST00000714431.1(transcript)|ensembl:ENST00000714432.1(transcript)|ensembl:ENST00000714433.1(transcript)|ensembl:ENST00000714434.1(transcript)|ensembl:ENST00000714435.1(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001875""(lipopolysaccharide immune receptor activity)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006691""(leukotriene metabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0007252""(I-kappaB phosphorylation)|go:""GO:0007612""(learning)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014005""(microglia development)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0032289""(central nervous system myelin formation)|go:""GO:0032570""(response to progesterone)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032741""(positive regulation of interleukin-18 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032868""(response to insulin)|go:""GO:0034134""(toll-like receptor 2 signaling pathway)|go:""GO:0035325""(Toll-like receptor binding)|go:""GO:0035354""(Toll-like receptor 1-Toll-like receptor 2 protein complex)|go:""GO:0035355""(Toll-like receptor 2-Toll-like receptor 6 protein complex)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042495""(detection of triacyl bacterial lipopeptide)|go:""GO:0042496""(detection of diacyl bacterial lipopeptide)|go:""GO:0042497""(triacyl lipopeptide binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042834""(peptidoglycan binding)|go:""GO:0042995""(cell projection)|go:""GO:0043235""(receptor complex)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046209""(nitric oxide metabolic process)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051607""(defense response to virus)|go:""GO:0051770""(obsolete positive regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0051964""(negative regulation of synapse assembly)|go:""GO:0061809""(NAD+ nucleosidase activity, cyclic ADP-ribose generating)|go:""GO:0070542""(response to fatty acid)|go:""GO:0071221""(cellular response to bacterial lipopeptide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071726""(cellular response to diacyl bacterial lipopeptide)|go:""GO:0071727""(cellular response to triacyl bacterial lipopeptide)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903974""(positive regulation of cellular response to macrophage colony-stimulating factor stimulus)|go:""GO:1904466""(positive regulation of matrix metallopeptidase secretion)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897|mint:O60603|rcsb pdb:1FYW|rcsb pdb:1FYX|rcsb pdb:1O77|rcsb pdb:2Z7X|rcsb pdb:2Z80|rcsb pdb:6NIG|rcsb pdb:8AR0|reactome:R-HSA-1236974|reactome:R-HSA-1461957|reactome:R-HSA-166058|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-9833110|refseq:NP_003255.2|refseq:XP_016864062.1|refseq:XP_016864063.1|refseq:XP_016864064.1|refseq:XP_016864065.1|refseq:NP_001305716.1|refseq:NP_001305718.1|refseq:NP_001305719.1|refseq:NP_001305720.1|refseq:NP_001305722.1|refseq:NP_001305725.1|refseq:NP_001305724.1|refseq:XP_011530517.1|refseq:XP_011530518.1|dip:DIP-35138N|panther:PTHR24365(orthology-group)"	-	-	-	figure legend:f6a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens THP-1 acute monocytic leukemia cell)	-	2014/01/16	2025/03/31	rogid:Mmdpw6fp1Vhn7cvxob30j/v/KrI83332	rogid:6xdppMwVYR7qWpDocSsqwvocdU89606	intact-crc:B875B6D00CF78E68|rigid:r1R0pASnvn7hleNgA12165XxADs	false	his tag:?-?	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P9WIG7	uniprotkb:O60603	intact:EBI-9086211|uniprotkb:L0TGV1|uniprotkb:Q8VIR8|uniprotkb:Q79F93	intact:EBI-973722|uniprotkb:O15454|uniprotkb:Q8NI00|ensembl:ENSP00000260010.6|ensembl:ENSP00000493968.2|ensembl:ENSP00000494425.1|ensembl:ENSP00000495339.1|ensembl:ENSP00000496208.2|ensembl:ENSP00000496676.2|ensembl:ENSP00000519700.1|ensembl:ENSP00000519701.1|ensembl:ENSP00000519702.1|ensembl:ENSP00000519703.1|ensembl:ENSP00000519704.1|uniprotkb:B3Y612|uniprotkb:D1CS45|uniprotkb:D1CS48|uniprotkb:D1CS49	psi-mi:pe35_myctu(display_long)|uniprotkb:PE35(gene name)|psi-mi:PE35(display_short)|uniprotkb:Rv3872(locus name)	psi-mi:tlr2_human(display_long)|uniprotkb:Toll/interleukin-1 receptor-like protein 4(gene name synonym)|uniprotkb:TLR2(gene name)|psi-mi:TLR2(display_short)|uniprotkb:TIL4(gene name synonym)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Tiwari et al. (2014)	pubmed:24467650|imex:IM-22080	"taxid:83332(myctu)|taxid:83332(""Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9086396|imex:IM-22080-5	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0009986""(cell surface)|interpro:IPR000084(PE N-terminal)|refseq:YP_178021.1|refseq:WP_003912361.1|mint:P9WIG7"	"ensembl:ENSG00000137462.10(gene)|ensembl:ENST00000260010.7(transcript)|ensembl:ENST00000642580.1(transcript)|ensembl:ENST00000642700.2(transcript)|ensembl:ENST00000643501.2(transcript)|ensembl:ENST00000646219.2(transcript)|ensembl:ENST00000646900.2(transcript)|ensembl:ENST00000714431.1(transcript)|ensembl:ENST00000714432.1(transcript)|ensembl:ENST00000714433.1(transcript)|ensembl:ENST00000714434.1(transcript)|ensembl:ENST00000714435.1(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001875""(lipopolysaccharide immune receptor activity)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006691""(leukotriene metabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0007252""(I-kappaB phosphorylation)|go:""GO:0007612""(learning)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014005""(microglia development)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0032289""(central nervous system myelin formation)|go:""GO:0032570""(response to progesterone)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032741""(positive regulation of interleukin-18 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032868""(response to insulin)|go:""GO:0034134""(toll-like receptor 2 signaling pathway)|go:""GO:0035325""(Toll-like receptor binding)|go:""GO:0035354""(Toll-like receptor 1-Toll-like receptor 2 protein complex)|go:""GO:0035355""(Toll-like receptor 2-Toll-like receptor 6 protein complex)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0038124""(""toll-like receptor TLR6:TLR2 signaling pathway"")|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042495""(detection of triacyl bacterial lipopeptide)|go:""GO:0042496""(detection of diacyl bacterial lipopeptide)|go:""GO:0042497""(triacyl lipopeptide binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042834""(peptidoglycan binding)|go:""GO:0042995""(cell projection)|go:""GO:0043235""(receptor complex)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046209""(nitric oxide metabolic process)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051607""(defense response to virus)|go:""GO:0051770""(obsolete positive regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0051964""(negative regulation of synapse assembly)|go:""GO:0061809""(NAD+ nucleosidase activity, cyclic ADP-ribose generating)|go:""GO:0070542""(response to fatty acid)|go:""GO:0071221""(cellular response to bacterial lipopeptide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071726""(cellular response to diacyl bacterial lipopeptide)|go:""GO:0071727""(cellular response to triacyl bacterial lipopeptide)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903974""(positive regulation of cellular response to macrophage colony-stimulating factor stimulus)|go:""GO:1904466""(positive regulation of matrix metallopeptidase secretion)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897|mint:O60603|rcsb pdb:1FYW|rcsb pdb:1FYX|rcsb pdb:1O77|rcsb pdb:2Z7X|rcsb pdb:2Z80|rcsb pdb:6NIG|rcsb pdb:8AR0|reactome:R-HSA-1236974|reactome:R-HSA-1461957|reactome:R-HSA-166058|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-9833110|refseq:NP_003255.2|refseq:XP_016864062.1|refseq:XP_016864063.1|refseq:XP_016864064.1|refseq:XP_016864065.1|refseq:NP_001305716.1|refseq:NP_001305718.1|refseq:NP_001305719.1|refseq:NP_001305720.1|refseq:NP_001305722.1|refseq:NP_001305725.1|refseq:NP_001305724.1|refseq:XP_011530517.1|refseq:XP_011530518.1|dip:DIP-35138N|panther:PTHR24365(orthology-group)"	-	-	-	figure legend:f6a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens THP-1 acute monocytic leukemia cell)	-	2014/01/16	2025/03/31	rogid:25izNArm9+0YQMaKw0Aky9ZeB+I83332	rogid:6xdppMwVYR7qWpDocSsqwvocdU89606	intact-crc:4E62DDA595A77B6B|rigid:xj9t0IxAzc1G4w8VmT+LUl6N0IE	false	his tag:?-?	-	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99XU0	uniprotkb:P02760	intact:EBI-8852705|uniprotkb:Q48WC7	intact:EBI-2115136|uniprotkb:P00977|uniprotkb:P02759|uniprotkb:P78491|uniprotkb:Q2TU33|uniprotkb:Q5TBD7|uniprotkb:Q9UC58|uniprotkb:Q9UDI8|ensembl:ENSP00000265132.3	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:ambp_human(display_long)|uniprotkb:AMBP(gene name)|psi-mi:AMBP(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:ITIL(gene name synonym)|uniprotkb:Protein HC(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-8852714|imex:IM-21724-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	"refseq:NP_001624.1|panther:PTHR46676(orthology-group)|ensembl:ENSG00000106927.12(gene)|ensembl:ENST00000265132.8(transcript)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007565""(female pregnancy)|go:""GO:0009986""(cell surface)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019862""(IgA binding)|go:""GO:0020037""(heme binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042167""(heme catabolic process)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0046904""(calcium oxalate binding)|go:""GO:0050777""(negative regulation of immune response)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR002968(Alpha-1-microglobulin)|interpro:IPR012674(Calycin)|interpro:IPR020901|interpro:IPR022272|interpro:IPR029856|interpro:IPR036880|mint:P02760|rcsb pdb:1BIK|rcsb pdb:3QKG|rcsb pdb:4ES7|rcsb pdb:4U30|rcsb pdb:6EJ7|rcsb pdb:6EJ8|rcsb pdb:6EJ9|rcsb pdb:6EJA|rcsb pdb:6EJB|rcsb pdb:6EJC|rcsb pdb:6EJD|reactome:R-HSA-2168880"	-	-	-	figure legend:5, table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/18	2025/03/25	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:os91tgT4TUMZ1qCf3SRbW5mwlGI9606	intact-crc:B48435DC28A0E260|rigid:0FyaooVffJledqorn6hPoYkexvg	false	tandem tag:n-n|sufficient binding region:3-98	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99XU0	uniprotkb:P04275	intact:EBI-8852705|uniprotkb:Q48WC7	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-8852714|imex:IM-21724-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	-	-	-	figure legend:5, table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/18	2025/03/25	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:B48435DC28A0E260|rigid:0FyaooVffJledqorn6hPoYkexvg	false	tandem tag:n-n|sufficient binding region:3-98	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99XU0	uniprotkb:P01009	intact:EBI-8852705|uniprotkb:Q48WC7	intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068.4|ensembl:ENSP00000376802.4|ensembl:ENSP00000376803.4|ensembl:ENSP00000385960.4|ensembl:ENSP00000390299.1|ensembl:ENSP00000408474.1|ensembl:ENSP00000416066.1|ensembl:ENSP00000416354.3|ensembl:ENSP00000490054.1	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-8852714|imex:IM-21724-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	"efo:""Orphanet:178396""|efo:""Orphanet:586""|efo:""Orphanet:60""|dip:DIP-35493N|ensembl:ENSG00000197249.14(gene)|ensembl:ENST00000355814.8(transcript)|ensembl:ENST00000393087.9(transcript)|ensembl:ENST00000393088.8(transcript)|ensembl:ENST00000404814.8(transcript)|ensembl:ENST00000437397.5(transcript)|ensembl:ENST00000440909.5(transcript)|ensembl:ENST00000448921.5(transcript)|ensembl:ENST00000449399.7(transcript)|ensembl:ENST00000636712.1(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006953""(acute-phase response)|go:""GO:0007596""(blood coagulation)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1D5S|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:8P4J|rcsb pdb:8P4U|rcsb pdb:8PI2|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275|refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|panther:PTHR11461(orthology-group)"	-	-	-	figure legend:5, table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/18	2025/03/25	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606	intact-crc:B48435DC28A0E260|rigid:0FyaooVffJledqorn6hPoYkexvg	false	tandem tag:n-n|sufficient binding region:3-98	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99XU0	uniprotkb:P02768	intact:EBI-8852705|uniprotkb:Q48WC7	intact:EBI-714423|uniprotkb:Q645G4|uniprotkb:O95574|uniprotkb:P04277|uniprotkb:Q13140|uniprotkb:Q68DN5|uniprotkb:Q6UXK4|uniprotkb:Q86YG0|uniprotkb:Q9P157|uniprotkb:Q9P1I7|uniprotkb:Q9UHS3|uniprotkb:Q9UJZ0|ensembl:ENSP00000295897.4|intact:EBI-7301844|intact:MINT-1161169|uniprotkb:E7ESS9|uniprotkb:Q8IUK7	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:albu_human(display_long)|uniprotkb:GIG42(orf name)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)|uniprotkb:GIG20(orf name)	"psi-mi:""MI:0096""(pull down)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-8852714|imex:IM-21724-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	"efo:""Orphanet:86816""|go:""GO:0005788""(endoplasmic reticulum lumen)|ensembl:ENSG00000163631.19(gene)|ensembl:ENST00000295897.9(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005504""(fatty acid binding)|go:""GO:0005507""(copper ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0015643""(toxic substance binding)|go:""GO:0016209""(antioxidant activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051902""(negative regulation of mitochondrial depolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0072732""(cellular response to calcium ion starvation)|go:""GO:0140272""(exogenous protein binding)|go:""GO:1903981""(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P02768|rcsb pdb:1AO6|rcsb pdb:1BJ5|rcsb pdb:1BKE|rcsb pdb:1BM0|rcsb pdb:1E78|rcsb pdb:1E7A|rcsb pdb:1E7B|rcsb pdb:1E7C|rcsb pdb:1E7E|rcsb pdb:1E7F|rcsb pdb:1E7G|rcsb pdb:1E7H|rcsb pdb:1E7I|rcsb pdb:1GNI|rcsb pdb:1GNJ|rcsb pdb:1H9Z|rcsb pdb:1HA2|rcsb pdb:1HK1|rcsb pdb:1HK2|rcsb pdb:1HK3|rcsb pdb:1HK4|rcsb pdb:1HK5|rcsb pdb:1N5U|rcsb pdb:1O9X|rcsb pdb:1TF0|rcsb pdb:1UOR|rcsb pdb:1YSX|rcsb pdb:2BX8|rcsb pdb:2BXA|rcsb pdb:2BXB|rcsb pdb:2BXC|rcsb pdb:2BXD|rcsb pdb:2BXE|rcsb pdb:2BXF|rcsb pdb:2BXG|rcsb pdb:2BXH|rcsb pdb:2BXI|rcsb pdb:2BXK|rcsb pdb:2BXL|rcsb pdb:2BXM|rcsb pdb:2BXN|rcsb pdb:2BXO|rcsb pdb:2BXP|rcsb pdb:2BXQ|rcsb pdb:2ESG|rcsb pdb:2I2Z|rcsb pdb:2I30|rcsb pdb:2N0X|rcsb pdb:2VDB|rcsb pdb:2VUE|rcsb pdb:2VUF|rcsb pdb:2XSI|rcsb pdb:2XVQ|rcsb pdb:2XVU|rcsb pdb:2XVV|rcsb pdb:2XVW|rcsb pdb:2XW0|rcsb pdb:2XW1|rcsb pdb:2YDF|rcsb pdb:3A73|rcsb pdb:3B9L|rcsb pdb:3B9M|rcsb pdb:3CX9|rcsb pdb:3JQZ|rcsb pdb:3JRY|rcsb pdb:3LU6|rcsb pdb:3LU7|rcsb pdb:3LU8|rcsb pdb:3SQJ|rcsb pdb:3TDL|rcsb pdb:3UIV|rcsb pdb:4BKE|rcsb pdb:4E99|rcsb pdb:4EMX|rcsb pdb:4G03|rcsb pdb:4G04|rcsb pdb:4HGK|rcsb pdb:4HGM|rcsb pdb:4IW1|rcsb pdb:4IW2|rcsb pdb:4K2C|rcsb pdb:4K71|rcsb pdb:4L8U|rcsb pdb:4L9K|rcsb pdb:4L9Q|rcsb pdb:4LA0|rcsb pdb:4LB2|rcsb pdb:4LB9|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4S1Y|rcsb pdb:4Z69|rcsb pdb:5FUO|rcsb pdb:5GIX|rcsb pdb:5GIY|rcsb pdb:5ID7|rcsb pdb:5IFO|rcsb pdb:5IJF|rcsb pdb:5UJB|rcsb pdb:5VNW|rcsb pdb:5X52|rcsb pdb:5YB1|rcsb pdb:5YOQ|rcsb pdb:5Z0B|rcsb pdb:6A7P|rcsb pdb:6EZQ|rcsb pdb:6JE7|rcsb pdb:6L4K|rcsb pdb:6M4R|rcsb pdb:6M58|rcsb pdb:6M5D|rcsb pdb:6M5E|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R7S|rcsb pdb:6WUW|rcsb pdb:6XV0|rcsb pdb:6YG9|rcsb pdb:6ZL1|rcsb pdb:7A9C|rcsb pdb:7AAE|rcsb pdb:7AAI|rcsb pdb:7D6J|rcsb pdb:7DJN|rcsb pdb:7DL4|rcsb pdb:7EEK|rcsb pdb:7FFR|rcsb pdb:7FFS|rcsb pdb:7JWN|rcsb pdb:7QFE|rcsb pdb:7VR0|rcsb pdb:7VR9|rcsb pdb:7WKZ|rcsb pdb:7WLF|rcsb pdb:7WOJ|rcsb pdb:7WOK|rcsb pdb:7WZ9|rcsb pdb:7X7X|rcsb pdb:7Y2D|rcsb pdb:7Z57|rcsb pdb:8A9Q|rcsb pdb:8CKS|rcsb pdb:8EW4|rcsb pdb:8EW7|rcsb pdb:8EY5|rcsb pdb:8H0O|rcsb pdb:8ISM|rcsb pdb:8ITR|rcsb pdb:8ITT|rcsb pdb:8J8E|rcsb pdb:8K1Y|rcsb pdb:8OI2|rcsb pdb:8Q3F|rcsb pdb:8RCO|rcsb pdb:8RCP|rcsb pdb:8RGK|rcsb pdb:8RGL|rcsb pdb:8VAC|rcsb pdb:8VAE|rcsb pdb:8VAF|rcsb pdb:8YXA|rcsb pdb:8YXB|rcsb pdb:8Z8V|rcsb pdb:9CSG|reactome:R-HSA-114608|reactome:R-HSA-159418|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2168880|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-8964058|reactome:R-HSA-9707564|reactome:R-HSA-9749641|reactome:R-HSA-9757110|reactome:R-HSA-9793528|refseq:NP_000468.1|dip:DIP-29902N|panther:PTHR11385(orthology-group)"	-	-	-	figure legend:5, table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/18	2025/03/25	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606	intact-crc:B48435DC28A0E260|rigid:0FyaooVffJledqorn6hPoYkexvg	false	tandem tag:n-n|sufficient binding region:3-98	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99XU0	uniprotkb:P02647	intact:EBI-8852705|uniprotkb:Q48WC7	intact:EBI-701692|uniprotkb:Q6LDN9|uniprotkb:Q6Q785|uniprotkb:A8K866|uniprotkb:Q9UCS8|uniprotkb:Q9UCT8|ensembl:ENSP00000236850.3|ensembl:ENSP00000352471.2|ensembl:ENSP00000364469.1|ensembl:ENSP00000364472.1	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:apoa1_human(display_long)|uniprotkb:APOA1(gene name)|psi-mi:APOA1(display_short)|uniprotkb:Apolipoprotein A1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-8852714|imex:IM-21724-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	"ensembl:ENSG00000118137.10(gene)|ensembl:ENST00000236850.5(transcript)|ensembl:ENST00000359492.6(transcript)|ensembl:ENST00000375320.5(transcript)|ensembl:ENST00000375323.5(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0002719""(negative regulation of cytokine production involved in immune response)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005769""(early endosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006656""(phosphatidylcholine biosynthetic process)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008035""(high-density lipoprotein particle binding)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008211""(glucocorticoid metabolic process)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0010903""(negative regulation of very-low-density lipoprotein particle remodeling)|go:""GO:0015485""(cholesterol binding)|go:""GO:0018158""(protein oxidation)|go:""GO:0018206""(peptidyl-methionine modification)|go:""GO:0019899""(enzyme binding)|go:""GO:0019915""(lipid storage)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030300""(regulation of intestinal cholesterol absorption)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030325""(adrenal gland development)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032489""(regulation of Cdc42 protein signal transduction)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0033700""(phospholipid efflux)|go:""GO:0034115""(negative regulation of heterotypic cell-cell adhesion)|go:""GO:0034190""(apolipoprotein receptor binding)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034361""(very-low-density lipoprotein particle)|go:""GO:0034362""(low-density lipoprotein particle)|go:""GO:0034364""(high-density lipoprotein particle)|go:""GO:0034366""(spherical high-density lipoprotein particle)|go:""GO:0034375""(high-density lipoprotein particle remodeling)|go:""GO:0034380""(high-density lipoprotein particle assembly)|go:""GO:0034384""(high-density lipoprotein particle clearance)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0042158""(lipoprotein biosynthetic process)|go:""GO:0042627""(chylomicron)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043534""(blood vessel endothelial cell migration)|go:""GO:0043691""(reverse cholesterol transport)|go:""GO:0045499""(chemorepellent activity)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0050821""(protein stabilization)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051180""(vitamin transport)|go:""GO:0051345""(positive regulation of hydrolase activity)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0055090""(acylglycerol homeostasis)|go:""GO:0055091""(phospholipid homeostasis)|go:""GO:0060228""(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:""GO:0060354""(negative regulation of cell adhesion molecule production)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070328""(triglyceride homeostasis)|go:""GO:0070508""(cholesterol import)|go:""GO:0070653""(high-density lipoprotein particle receptor binding)|go:""GO:0071402""(cellular response to lipoprotein particle stimulus)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0072562""(blood microparticle)|go:""GO:0090205""(positive regulation of cholesterol metabolic process)|go:""GO:0120020""(cholesterol transfer activity)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902995""(positive regulation of phospholipid efflux)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1905920""(positive regulation of CoA-transferase activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|interpro:IPR050163|mint:P02647|rcsb pdb:1AV1|rcsb pdb:1GW3|rcsb pdb:1GW4|rcsb pdb:1ODP|rcsb pdb:1ODQ|rcsb pdb:1ODR|rcsb pdb:2MSC|rcsb pdb:2MSD|rcsb pdb:2MSE|rcsb pdb:2N5E|rcsb pdb:3K2S|rcsb pdb:3R2P|rcsb pdb:4V6M|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CLZ|rcsb pdb:6CM1|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:7KJR|rcsb pdb:7RSC|rcsb pdb:7RSE|rcsb pdb:8EQS|reactome:R-HSA-114608|reactome:R-HSA-1369062|reactome:R-HSA-1989781|reactome:R-HSA-2168880|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-5682113|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963896|reactome:R-HSA-8963901|reactome:R-HSA-8964011|reactome:R-HSA-8964058|reactome:R-HSA-9707616|reactome:R-HSA-975634|reactome:R-HSA-977225|refseq:NP_000030.1|refseq:NP_001304946.1|refseq:NP_001304947.1|refseq:NP_001304950.1|efo:""Orphanet:425""|efo:""Orphanet:93560""|dip:DIP-29619N|panther:PTHR18976(orthology-group)"	-	-	-	figure legend:5, table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/18	2025/03/25	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:yEzPDeU8Uu/43dkLLOBAy6ey1vs9606	intact-crc:B48435DC28A0E260|rigid:0FyaooVffJledqorn6hPoYkexvg	false	tandem tag:n-n|sufficient binding region:3-98	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99XU0	uniprotkb:P01024	intact:EBI-8852705|uniprotkb:Q48WC7	intact:EBI-905851|uniprotkb:A7E236|ensembl:ENSP00000245907.4	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:co3_human(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)|uniprotkb:CPAMD1(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-8852714|imex:IM-21724-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	"efo:""Orphanet:280133""|efo:""Orphanet:544472""|ensembl:ENSG00000125730.18(gene)|ensembl:ENST00000245907.11(transcript)|go:""GO:0001798""(positive regulation of type IIa hypersensitivity)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001970""(positive regulation of activation of membrane attack complex)|go:""GO:0002430""(complement receptor mediated signaling pathway)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007165""(signal transduction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0009617""(response to bacterium)|go:""GO:0009986""(cell surface)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010828""(positive regulation of D-glucose transmembrane transport)|go:""GO:0010866""(regulation of triglyceride biosynthetic process)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0016322""(neuron remodeling)|go:""GO:0031715""(C5L2 anaphylatoxin chemotactic receptor binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035846""(oviduct epithelium development)|go:""GO:0042113""(B cell activation)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0097278""(complement-dependent cytotoxicity)|go:""GO:0150062""(complement-mediated synapse pruning)|go:""GO:0150064""(vertebrate eye-specific patterning)|go:""GO:2000427""(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|interpro:IPR047565|interpro:IPR048848|interpro:IPR049466|interpro:IPR050473|mint:P01024|rcsb pdb:1C3D|rcsb pdb:1GHQ|rcsb pdb:1W2S|rcsb pdb:2A73|rcsb pdb:2A74|rcsb pdb:2GOX|rcsb pdb:2I07|rcsb pdb:2ICE|rcsb pdb:2ICF|rcsb pdb:2NOJ|rcsb pdb:2QKI|rcsb pdb:2WII|rcsb pdb:2WIN|rcsb pdb:2WY7|rcsb pdb:2WY8|rcsb pdb:2XQW|rcsb pdb:2XWB|rcsb pdb:2XWJ|rcsb pdb:3D5R|rcsb pdb:3D5S|rcsb pdb:3G6J|rcsb pdb:3L3O|rcsb pdb:3L5N|rcsb pdb:3NMS|rcsb pdb:3OED|rcsb pdb:3OHX|rcsb pdb:3OXU|rcsb pdb:3RJ3|rcsb pdb:3T4A|rcsb pdb:4HW5|rcsb pdb:4HWJ|rcsb pdb:4I6O|rcsb pdb:4M76|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5FO7|rcsb pdb:5FO8|rcsb pdb:5FO9|rcsb pdb:5FOA|rcsb pdb:5FOB|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:6EHG|rcsb pdb:6RMT|rcsb pdb:6RMU|rcsb pdb:6RUR|rcsb pdb:6RUV|rcsb pdb:6S0B|rcsb pdb:6YO6|rcsb pdb:7AKK|rcsb pdb:7BAG|rcsb pdb:7NOZ|rcsb pdb:7PI6|rcsb pdb:7QIV|rcsb pdb:7TV9|rcsb pdb:7UE9|rcsb pdb:7ZGK|rcsb pdb:8ENU|rcsb pdb:8EOK|rcsb pdb:8HK2|rcsb pdb:8I9L|rcsb pdb:8OQ3|rcsb pdb:8OVB|rcsb pdb:8UH2|rcsb pdb:8UIN|reactome:R-HSA-173736|reactome:R-HSA-174577|reactome:R-HSA-198933|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-418594|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9660826|reactome:R-HSA-977606|refseq:NP_000055.2|dip:DIP-35180N|panther:PTHR11412(orthology-group)"	-	-	-	figure legend:5, table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/18	2025/03/25	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:6Axa89cCPpUXFsLnd7sCurZzLYI9606	intact-crc:B48435DC28A0E260|rigid:0FyaooVffJledqorn6hPoYkexvg	false	tandem tag:n-n|sufficient binding region:3-98	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99XU0	uniprotkb:P08603	intact:EBI-8852705|uniprotkb:Q48WC7	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-8852714|imex:IM-21724-1	intact-miscore:0.35	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	-	-	-	figure legend:5, table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/18	2025/03/25	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	intact-crc:B48435DC28A0E260|rigid:0FyaooVffJledqorn6hPoYkexvg	false	tandem tag:n-n|sufficient binding region:3-98	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99XU0	uniprotkb:P04196	intact:EBI-8852705|uniprotkb:Q48WC7	intact:EBI-3915012|uniprotkb:B9EK35|uniprotkb:D3DNU7|ensembl:ENSP00000232003.4	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:hrg_human(display_long)|uniprotkb:HRG(gene name)|psi-mi:HRG(display_short)|uniprotkb:Histidine-proline-rich glycoprotein(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-8852714|imex:IM-21724-1	intact-miscore:0.60	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	"dip:DIP-47264N|ensembl:ENSG00000113905.5(gene)|ensembl:ENST00000232003.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0002839""(positive regulation of immune response to tumor cell)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010543""(regulation of platelet activation)|go:""GO:0010593""(negative regulation of lamellipodium assembly)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0020037""(heme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033629""(negative regulation of cell adhesion mediated by integrin)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050832""(defense response to fungus)|go:""GO:0051838""(cytolysis by host of symbiont cells)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1900747""(negative regulation of vascular endothelial growth factor signaling pathway)|go:""GO:2000504""(positive regulation of blood vessel remodeling)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR046350|interpro:IPR050735|mint:P04196|reactome:R-HSA-114608|reactome:R-HSA-75205|refseq:NP_000403.1|efo:""Orphanet:217467""|panther:PTHR13814(orthology-group)"	-	-	-	figure legend:5, table 2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/18	2025/03/25	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:o/MnMkd+IKLRtprrFoOapUuoVEs9606	intact-crc:B48435DC28A0E260|rigid:0FyaooVffJledqorn6hPoYkexvg	false	tandem tag:n-n|sufficient binding region:3-98	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99XU0	uniprotkb:P04196	intact:EBI-8852705|uniprotkb:Q48WC7	intact:EBI-3915012|uniprotkb:B9EK35|uniprotkb:D3DNU7|ensembl:ENSP00000232003.4	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:hrg_human(display_long)|uniprotkb:HRG(gene name)|psi-mi:HRG(display_short)|uniprotkb:Histidine-proline-rich glycoprotein(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-8853742|imex:IM-21724-3	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	"dip:DIP-47264N|ensembl:ENSG00000113905.5(gene)|ensembl:ENST00000232003.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0002839""(positive regulation of immune response to tumor cell)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010543""(regulation of platelet activation)|go:""GO:0010593""(negative regulation of lamellipodium assembly)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0020037""(heme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033629""(negative regulation of cell adhesion mediated by integrin)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050832""(defense response to fungus)|go:""GO:0051838""(cytolysis by host of symbiont cells)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1900747""(negative regulation of vascular endothelial growth factor signaling pathway)|go:""GO:2000504""(positive regulation of blood vessel remodeling)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR046350|interpro:IPR050735|mint:P04196|reactome:R-HSA-114608|reactome:R-HSA-75205|refseq:NP_000403.1|efo:""Orphanet:217467""|panther:PTHR13814(orthology-group)"	-	-	-	figure legend:6a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:12.0x10^-6(molar)	2013/11/18	2024/11/14	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:o/MnMkd+IKLRtprrFoOapUuoVEs9606	intact-crc:165FF0BBDDDCA239|rigid:8vd8mDLchrTfBx0snqtYyA36teY	false	sufficient binding region:3-98	his tag:c-c	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99XU0	intact:EBI-8853818	intact:EBI-8852705|uniprotkb:Q48WC7	-	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:hrgshort(display_short)|psi-mi:EBI-8853818(display_long)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-8853767|imex:IM-21724-4	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0327""(peptide)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	uniprotkb:P04196(see-also)	-	-	-	figure legend:6d|comment:The assay detects two binding sites with different Kds for this interaction.|variable_condition:No pH values given for this interaction.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:12.0x10^-9 ~4.0(molar)|kd:500.0x10^-9 ~100.0(molar)	2013/11/18	2024/11/14	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:hv2GWASB9EeFcnBhJyGe2WTClNw9606	intact-crc:839CA0323379C2D5|rigid:vlL9r0bSnyaGRnxAf+0wBlvDWe0	false	sufficient binding region:3-98	-	1	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99XU0	uniprotkb:P04196	intact:EBI-8852705|uniprotkb:Q48WC7	intact:EBI-3915012|uniprotkb:B9EK35|uniprotkb:D3DNU7|ensembl:ENSP00000232003.4	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	psi-mi:hrg_human(display_long)|uniprotkb:HRG(gene name)|psi-mi:HRG(display_short)|uniprotkb:Histidine-proline-rich glycoprotein(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-9635836|imex:IM-21724-6	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	"dip:DIP-47264N|ensembl:ENSG00000113905.5(gene)|ensembl:ENST00000232003.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0002839""(positive regulation of immune response to tumor cell)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010543""(regulation of platelet activation)|go:""GO:0010593""(negative regulation of lamellipodium assembly)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0020037""(heme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033629""(negative regulation of cell adhesion mediated by integrin)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050832""(defense response to fungus)|go:""GO:0051838""(cytolysis by host of symbiont cells)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1900747""(negative regulation of vascular endothelial growth factor signaling pathway)|go:""GO:2000504""(positive regulation of blood vessel remodeling)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR046350|interpro:IPR050735|mint:P04196|reactome:R-HSA-114608|reactome:R-HSA-75205|refseq:NP_000403.1|efo:""Orphanet:217467""|panther:PTHR13814(orthology-group)"	-	-	-	figure legend:6b|variable_condition:pH 5.5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:130.0x10^-9(molar)	2013/11/18	2024/11/14	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	rogid:o/MnMkd+IKLRtprrFoOapUuoVEs9606	intact-crc:038D2D87AC6B2D21|rigid:8vd8mDLchrTfBx0snqtYyA36teY	false	sufficient binding region:3-98	strep ii tag:c-c	1	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P04196	uniprotkb:Q99XU0	intact:EBI-3915012|uniprotkb:B9EK35|uniprotkb:D3DNU7|ensembl:ENSP00000232003.4	intact:EBI-8852705|uniprotkb:Q48WC7	psi-mi:hrg_human(display_long)|uniprotkb:HRG(gene name)|psi-mi:HRG(display_short)|uniprotkb:Histidine-proline-rich glycoprotein(gene name synonym)	psi-mi:q99xu0_strp1(display_long)|uniprotkb:SPy_2034(locus name)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Wisniewska et al. (2014)	imex:IM-21724|pubmed:24825900	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:301447(strp1)|taxid:301447(Streptococcus pyogenes serotype M1)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-9635867|imex:IM-21724-7	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-47264N|ensembl:ENSG00000113905.5(gene)|ensembl:ENST00000232003.5(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0002839""(positive regulation of immune response to tumor cell)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0008201""(heparin binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010543""(regulation of platelet activation)|go:""GO:0010593""(negative regulation of lamellipodium assembly)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0020037""(heme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033629""(negative regulation of cell adhesion mediated by integrin)|go:""GO:0042730""(fibrinolysis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050832""(defense response to fungus)|go:""GO:0051838""(cytolysis by host of symbiont cells)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1900747""(negative regulation of vascular endothelial growth factor signaling pathway)|go:""GO:2000504""(positive regulation of blood vessel remodeling)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR046350|interpro:IPR050735|mint:P04196|reactome:R-HSA-114608|reactome:R-HSA-75205|refseq:NP_000403.1|efo:""Orphanet:217467""|panther:PTHR13814(orthology-group)"	"interpro:IPR025384|rcsb pdb:4MER|rcsb pdb:4PZ1|go:""GO:0042802""(identical protein binding)|refseq:NP_269983.1"	-	-	-	figure legend:6c|comment:The assay detects two binding sites with different Kds for this interaction.|variable_condition:pH 7.5|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:40.0x10^-9(molar)|kd:200.0x10^-9(molar)	2013/11/18	2024/11/14	rogid:o/MnMkd+IKLRtprrFoOapUuoVEs9606	rogid:vWbGEsSbqeeS8bg2Z4KnIyh41fM301447	intact-crc:F5369AA6F14ABFF6|rigid:8vd8mDLchrTfBx0snqtYyA36teY	false	strep ii tag:c-c	sufficient binding region:3-98	-	1	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5ZUS4	uniprotkb:P06748	intact:EBI-8871796	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:q5zus4_legph(display_long)|uniprotkb:legAS4(gene name)|psi-mi:legAS4(display_short)|uniprotkb:lpg1718(locus name)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871793|imex:IM-21744-1	intact-miscore:0.27	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR046341|interpro:IPR002110(Ankyrin)|interpro:IPR001214(SET)|interpro:IPR044427|refseq:WP_010947445.1|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|rcsb pdb:5CZY|rcsb pdb:8SR6|rcsb pdb:8SWI|interpro:IPR036770|interpro:IPR050777|mint:Q5ZUS4|refseq:YP_095745.1"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	"go:""GO:0005730""(nucleolus)"	-	-	figure legend:f1b sf1c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2013/11/22	2025/03/31	rogid:AawiOw7oGh89g01s2RH9B++pPHg272624	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:FF522C664DBDB796|rigid:LTHVICCodZHozscobcPTx58Fd7c	false	green fluorescent protein tag:?-?|binding-associated region:21-63	-	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:P06748	uniprotkb:Q2STB6	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	intact:EBI-8872002	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	psi-mi:q2stb6_burta(display_long)|uniprotkb:BTH_I3341(locus name)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:271848(burta)|taxid:271848(""Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)"")"	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871999|imex:IM-21744-11	intact-miscore:0.27	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	"interpro:IPR046341|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR001214(SET)|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|interpro:IPR050777|mint:Q2STB6"	"go:""GO:0005730""(nucleolus)"	-	-	figure legend:f3b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2013/11/22	2025/03/31	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	rogid:i34otlKhtGJYW7W/4jqARrIeB8Y271848	intact-crc:23FF39C4FBF249E9|rigid:tt70wTRaL3/SiD/qAxScLSs1R10	false	-	green fluorescent protein tag:?-?	-	-	"psi-mi:""MI:0422""(immunostaining)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:A0A0H3LYM0	uniprotkb:P06748	intact:EBI-8871974	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:a0a0h3lym0_borbr(display_long)|uniprotkb:BB4970(locus name)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0416""(fluorescence microscopy)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	"taxid:257310(borbr)|taxid:257310(""Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0403""(colocalization)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871965|imex:IM-21744-10	intact-miscore:0.27	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR046341|uniprotkb:Q7WDL8(uniprot-removed-ac)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|interpro:IPR050777|mint:A0A0H3LYM0|refseq:WP_003815991.1"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	"go:""GO:0005730""(nucleolus)"	-	-	figure legend:f3b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2013/11/22	2025/03/31	rogid:3yYBcjbC/XoJLkdtYcYgi2Wa3Zw257310	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:AB164CBA82D0EB2D|rigid:Awet/I4NCWKttSisnG3+weA+RqM	false	green fluorescent protein tag:?-?	-	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0422""(immunostaining)"
uniprotkb:Q5ZUS4	uniprotkb:P45973	intact:EBI-8871796	intact:EBI-78219|uniprotkb:B2R8T9|ensembl:ENSP00000209875.4|ensembl:ENSP00000401009.2|ensembl:ENSP00000449207.1	psi-mi:q5zus4_legph(display_long)|uniprotkb:legAS4(gene name)|psi-mi:legAS4(display_short)|uniprotkb:lpg1718(locus name)	psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871821|imex:IM-21744-2	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR046341|interpro:IPR002110(Ankyrin)|interpro:IPR001214(SET)|interpro:IPR044427|refseq:WP_010947445.1|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|rcsb pdb:5CZY|rcsb pdb:8SR6|rcsb pdb:8SWI|interpro:IPR036770|interpro:IPR050777|mint:Q5ZUS4|refseq:YP_095745.1"	"refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|panther:PTHR22812(orthology-group)|dip:DIP-5986N|ensembl:ENSG00000094916.16(gene)|ensembl:ENST00000209875.9(transcript)|ensembl:ENST00000439541.6(transcript)|ensembl:ENST00000550411.5(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000776""(kinetochore)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000792""(heterochromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005730""(nucleolus)|go:""GO:0006974""(DNA damage response)|go:""GO:0010369""(chromocenter)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090734""(site of DNA damage)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR051219|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|rcsb pdb:8UXQ|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|reactome:R-HSA-9843940"	-	-	-	figure legend:f2a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/11/22	2025/03/31	rogid:AawiOw7oGh89g01s2RH9B++pPHg272624	rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606	intact-crc:CF5C44473786E789|rigid:zQfs7SLVPcG3isZXzgc/LRV0rnE	false	fusion protein:?-?|binding-associated region:1-114,248-545	fusion protein:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5ZUS4	uniprotkb:Q13185	intact:EBI-8871796	intact:EBI-78176|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6|ensembl:ENSP00000336687.4|ensembl:ENSP00000379670.2	psi-mi:q5zus4_legph(display_long)|uniprotkb:legAS4(gene name)|psi-mi:legAS4(display_short)|uniprotkb:lpg1718(locus name)	psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871848|imex:IM-21744-3	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR046341|interpro:IPR002110(Ankyrin)|interpro:IPR001214(SET)|interpro:IPR044427|refseq:WP_010947445.1|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|rcsb pdb:5CZY|rcsb pdb:8SR6|rcsb pdb:8SWI|interpro:IPR036770|interpro:IPR050777|mint:Q5ZUS4|refseq:YP_095745.1"	"refseq:NP_009207.2|refseq:NP_057671.2|panther:PTHR22812(orthology-group)|refseq:XP_005249668.1|dip:DIP-5985N|ensembl:ENSG00000122565.19(gene)|ensembl:ENST00000337620.8(transcript)|ensembl:ENST00000396386.7(transcript)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000779""(condensed chromosome, centromeric region)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000792""(heterochromatin)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005819""(spindle)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006974""(DNA damage response)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035985""(senescence-associated heterochromatin focus)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048511""(rhythmic process)|go:""GO:0061793""(chromatin lock complex)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0090734""(site of DNA damage)|go:""GO:1990226""(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|interpro:IPR051219|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|rcsb pdb:5T1I|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750"	-	-	-	figure legend:f2a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/11/22	2025/03/31	rogid:AawiOw7oGh89g01s2RH9B++pPHg272624	rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606	intact-crc:47FCBA934DE0F500|rigid:JR7JNBz7HFEQwN2eupCGe8pnaCQ	false	fusion protein:?-?|binding-associated region:1-114,248-545	fusion protein:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P45973	uniprotkb:Q5ZUS4	intact:EBI-78219|uniprotkb:B2R8T9|ensembl:ENSP00000209875.4|ensembl:ENSP00000401009.2|ensembl:ENSP00000449207.1	intact:EBI-8871796	psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym)	psi-mi:q5zus4_legph(display_long)|uniprotkb:legAS4(gene name)|psi-mi:legAS4(display_short)|uniprotkb:lpg1718(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871870|imex:IM-21744-4	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|panther:PTHR22812(orthology-group)|dip:DIP-5986N|ensembl:ENSG00000094916.16(gene)|ensembl:ENST00000209875.9(transcript)|ensembl:ENST00000439541.6(transcript)|ensembl:ENST00000550411.5(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000776""(kinetochore)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000792""(heterochromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005730""(nucleolus)|go:""GO:0006974""(DNA damage response)|go:""GO:0010369""(chromocenter)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090734""(site of DNA damage)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR051219|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|rcsb pdb:8UXQ|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|reactome:R-HSA-9843940"	"interpro:IPR046341|interpro:IPR002110(Ankyrin)|interpro:IPR001214(SET)|interpro:IPR044427|refseq:WP_010947445.1|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|rcsb pdb:5CZY|rcsb pdb:8SR6|rcsb pdb:8SWI|interpro:IPR036770|interpro:IPR050777|mint:Q5ZUS4|refseq:YP_095745.1"	-	-	-	figure legend:f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2013/11/22	2025/03/31	rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606	rogid:AawiOw7oGh89g01s2RH9B++pPHg272624	intact-crc:CE8A62DFA213E3C1|rigid:zQfs7SLVPcG3isZXzgc/LRV0rnE	false	myc tag:?-?	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q13185	uniprotkb:Q5ZUS4	intact:EBI-78176|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6|ensembl:ENSP00000336687.4|ensembl:ENSP00000379670.2	intact:EBI-8871796	psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym)	psi-mi:q5zus4_legph(display_long)|uniprotkb:legAS4(gene name)|psi-mi:legAS4(display_short)|uniprotkb:lpg1718(locus name)	"psi-mi:""MI:0006""(anti bait coimmunoprecipitation)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871878|imex:IM-21744-5	intact-miscore:0.51	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009207.2|refseq:NP_057671.2|panther:PTHR22812(orthology-group)|refseq:XP_005249668.1|dip:DIP-5985N|ensembl:ENSG00000122565.19(gene)|ensembl:ENST00000337620.8(transcript)|ensembl:ENST00000396386.7(transcript)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0000779""(condensed chromosome, centromeric region)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000792""(heterochromatin)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005819""(spindle)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006974""(DNA damage response)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035985""(senescence-associated heterochromatin focus)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048511""(rhythmic process)|go:""GO:0061793""(chromatin lock complex)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0090734""(site of DNA damage)|go:""GO:1990226""(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|interpro:IPR051219|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|rcsb pdb:5T1I|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750"	"interpro:IPR046341|interpro:IPR002110(Ankyrin)|interpro:IPR001214(SET)|interpro:IPR044427|refseq:WP_010947445.1|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|rcsb pdb:5CZY|rcsb pdb:8SR6|rcsb pdb:8SWI|interpro:IPR036770|interpro:IPR050777|mint:Q5ZUS4|refseq:YP_095745.1"	-	-	-	figure legend:f2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2013/11/22	2025/03/31	rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606	rogid:AawiOw7oGh89g01s2RH9B++pPHg272624	intact-crc:B50BC66FAC42C04E|rigid:JR7JNBz7HFEQwN2eupCGe8pnaCQ	false	myc tag:?-?	flag tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q5ZUS4	uniprotkb:P45973	intact:EBI-8871796	intact:EBI-78219|uniprotkb:B2R8T9|ensembl:ENSP00000209875.4|ensembl:ENSP00000401009.2|ensembl:ENSP00000449207.1	psi-mi:q5zus4_legph(display_long)|uniprotkb:legAS4(gene name)|psi-mi:legAS4(display_short)|uniprotkb:lpg1718(locus name)	psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871927|imex:IM-21744-7	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR046341|interpro:IPR002110(Ankyrin)|interpro:IPR001214(SET)|interpro:IPR044427|refseq:WP_010947445.1|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|rcsb pdb:5CZY|rcsb pdb:8SR6|rcsb pdb:8SWI|interpro:IPR036770|interpro:IPR050777|mint:Q5ZUS4|refseq:YP_095745.1"	"refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|panther:PTHR22812(orthology-group)|dip:DIP-5986N|ensembl:ENSG00000094916.16(gene)|ensembl:ENST00000209875.9(transcript)|ensembl:ENST00000439541.6(transcript)|ensembl:ENST00000550411.5(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000776""(kinetochore)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000792""(heterochromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005730""(nucleolus)|go:""GO:0006974""(DNA damage response)|go:""GO:0010369""(chromocenter)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090734""(site of DNA damage)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR051219|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|rcsb pdb:8UXQ|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|reactome:R-HSA-9843940"	-	-	-	figure legend:f2e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/22	2025/03/31	rogid:AawiOw7oGh89g01s2RH9B++pPHg272624	rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606	intact-crc:6D34D3A17BF34D09|rigid:zQfs7SLVPcG3isZXzgc/LRV0rnE	false	glutathione s tranferase tag:?-?	mutation disrupting interaction:165-165	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q5ZUS4	uniprotkb:P45973	intact:EBI-8871796	intact:EBI-78219|uniprotkb:B2R8T9|ensembl:ENSP00000209875.4|ensembl:ENSP00000401009.2|ensembl:ENSP00000449207.1	psi-mi:q5zus4_legph(display_long)|uniprotkb:legAS4(gene name)|psi-mi:legAS4(display_short)|uniprotkb:lpg1718(locus name)	psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871937|imex:IM-21744-8	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR046341|interpro:IPR002110(Ankyrin)|interpro:IPR001214(SET)|interpro:IPR044427|refseq:WP_010947445.1|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|rcsb pdb:5CZY|rcsb pdb:8SR6|rcsb pdb:8SWI|interpro:IPR036770|interpro:IPR050777|mint:Q5ZUS4|refseq:YP_095745.1"	"refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|panther:PTHR22812(orthology-group)|dip:DIP-5986N|ensembl:ENSG00000094916.16(gene)|ensembl:ENST00000209875.9(transcript)|ensembl:ENST00000439541.6(transcript)|ensembl:ENST00000550411.5(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000776""(kinetochore)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000792""(heterochromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005730""(nucleolus)|go:""GO:0006974""(DNA damage response)|go:""GO:0010369""(chromocenter)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090734""(site of DNA damage)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR051219|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|rcsb pdb:8UXQ|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|reactome:R-HSA-9843940"	-	-	-	figure legend:f2e|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/22	2025/03/31	rogid:AawiOw7oGh89g01s2RH9B++pPHg272624	rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606	intact-crc:29E5E57E68B65940|rigid:zQfs7SLVPcG3isZXzgc/LRV0rnE	false	glutathione s tranferase tag:?-?	mutation disrupting interaction:174-174	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q5ZUS4	uniprotkb:P45973	intact:EBI-8871796	intact:EBI-78219|uniprotkb:B2R8T9|ensembl:ENSP00000209875.4|ensembl:ENSP00000401009.2|ensembl:ENSP00000449207.1	psi-mi:q5zus4_legph(display_long)|uniprotkb:legAS4(gene name)|psi-mi:legAS4(display_short)|uniprotkb:lpg1718(locus name)	psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871904|imex:IM-21744-6	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR046341|interpro:IPR002110(Ankyrin)|interpro:IPR001214(SET)|interpro:IPR044427|refseq:WP_010947445.1|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|rcsb pdb:5CZY|rcsb pdb:8SR6|rcsb pdb:8SWI|interpro:IPR036770|interpro:IPR050777|mint:Q5ZUS4|refseq:YP_095745.1"	"refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|panther:PTHR22812(orthology-group)|dip:DIP-5986N|ensembl:ENSG00000094916.16(gene)|ensembl:ENST00000209875.9(transcript)|ensembl:ENST00000439541.6(transcript)|ensembl:ENST00000550411.5(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000776""(kinetochore)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000792""(heterochromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005730""(nucleolus)|go:""GO:0006974""(DNA damage response)|go:""GO:0010369""(chromocenter)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090734""(site of DNA damage)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR051219|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|rcsb pdb:8UXQ|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|reactome:R-HSA-9843940"	-	-	-	figure legend:f2d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/22	2025/03/31	rogid:AawiOw7oGh89g01s2RH9B++pPHg272624	rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606	intact-crc:26A6DF88C66A1AD9|rigid:zQfs7SLVPcG3isZXzgc/LRV0rnE	false	glutathione s tranferase tag:?-?	binding-associated region:119-191	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q5ZUS4	uniprotkb:P45973	intact:EBI-8871796	intact:EBI-78219|uniprotkb:B2R8T9|ensembl:ENSP00000209875.4|ensembl:ENSP00000401009.2|ensembl:ENSP00000449207.1	psi-mi:q5zus4_legph(display_long)|uniprotkb:legAS4(gene name)|psi-mi:legAS4(display_short)|uniprotkb:lpg1718(locus name)	psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Li et al. (2013)	imex:IM-21744|pubmed:23797873	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-8871947|imex:IM-21744-9	intact-miscore:0.59	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR046341|interpro:IPR002110(Ankyrin)|interpro:IPR001214(SET)|interpro:IPR044427|refseq:WP_010947445.1|go:""GO:0005694""(chromosome)|go:""GO:0016279""(protein-lysine N-methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0140938""(histone H3 methyltransferase activity)|rcsb pdb:5CZY|rcsb pdb:8SR6|rcsb pdb:8SWI|interpro:IPR036770|interpro:IPR050777|mint:Q5ZUS4|refseq:YP_095745.1"	"refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|panther:PTHR22812(orthology-group)|dip:DIP-5986N|ensembl:ENSG00000094916.16(gene)|ensembl:ENST00000209875.9(transcript)|ensembl:ENST00000439541.6(transcript)|ensembl:ENST00000550411.5(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000776""(kinetochore)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000792""(heterochromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005730""(nucleolus)|go:""GO:0006974""(DNA damage response)|go:""GO:0010369""(chromocenter)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090734""(site of DNA damage)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR051219|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|rcsb pdb:8UXQ|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|reactome:R-HSA-9843940"	-	-	-	figure legend:f2f|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/22	2025/03/31	rogid:AawiOw7oGh89g01s2RH9B++pPHg272624	rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606	intact-crc:7763A960B73DD7CC|rigid:zQfs7SLVPcG3isZXzgc/LRV0rnE	false	glutathione s tranferase tag:?-?|binding-associated region:21-61	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q93ED6	uniprotkb:P02751	intact:EBI-9826140	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q93ed6_9stre(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0071""(molecular sieving)"	Tiouajni et al. (2014)	pubmed:25290767|imex:IM-23207	taxid:148942(streptococcus equi subsp. equi)|taxid:148942(Streptococcus equi subsp. equi)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9826136|imex:IM-23207-1	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:5DCQ|interpro:IPR023849|interpro:IPR013552(Fibronectin-binding, signal sequence)|mint:Q93ED6|refseq:WP_052292771.1	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:f2a f2b f2c|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/09/30	2025/03/31	rogid:2L9anYvFpOUkmhq8YSuzVSRvRj0148942	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:27C8E4B16B8B3279|rigid:2x6nyRK5fqDzM/xmh7/uOUB+SuM	false	his tag:?-?|binding-associated region:219-264	binding-associated region:468-602	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q93ED6	uniprotkb:P02751	intact:EBI-9826140	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q93ed6_9stre(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Tiouajni et al. (2014)	pubmed:25290767|imex:IM-23207	taxid:148942(streptococcus equi subsp. equi)|taxid:148942(Streptococcus equi subsp. equi)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9826173|imex:IM-23207-2	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:5DCQ|interpro:IPR023849|interpro:IPR013552(Fibronectin-binding, signal sequence)|mint:Q93ED6|refseq:WP_052292771.1	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:f2c t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.3x10^-6(molar)	2014/09/30	2025/03/31	rogid:2L9anYvFpOUkmhq8YSuzVSRvRj0148942	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:F577E36A1ED5C673|rigid:2x6nyRK5fqDzM/xmh7/uOUB+SuM	false	his tag:?-?	binding-associated region:468-602	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q93ED6	uniprotkb:P02751	intact:EBI-9826140	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q93ed6_9stre(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Tiouajni et al. (2014)	pubmed:25290767|imex:IM-23207	taxid:148942(streptococcus equi subsp. equi)|taxid:148942(Streptococcus equi subsp. equi)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9826187|imex:IM-23207-3	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:5DCQ|interpro:IPR023849|interpro:IPR013552(Fibronectin-binding, signal sequence)|mint:Q93ED6|refseq:WP_052292771.1	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:f2a f2b t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.3x10^-6(molar)	2014/09/30	2025/03/31	rogid:2L9anYvFpOUkmhq8YSuzVSRvRj0148942	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:A2A136A0FCB06520|rigid:2x6nyRK5fqDzM/xmh7/uOUB+SuM	false	his tag:?-?|necessary binding region:219-264	binding-associated region:306-602	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q93ED6	uniprotkb:P02751	intact:EBI-9826140	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q93ed6_9stre(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Tiouajni et al. (2014)	pubmed:25290767|imex:IM-23207	taxid:148942(streptococcus equi subsp. equi)|taxid:148942(Streptococcus equi subsp. equi)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9826218|imex:IM-23207-5	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:5DCQ|interpro:IPR023849|interpro:IPR013552(Fibronectin-binding, signal sequence)|mint:Q93ED6|refseq:WP_052292771.1	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:f2d t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:9.2x10^-6(molar)	2014/09/30	2025/03/31	rogid:2L9anYvFpOUkmhq8YSuzVSRvRj0148942	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:481FF68C2183F648|rigid:2x6nyRK5fqDzM/xmh7/uOUB+SuM	false	tandem tag:?-?|binding-associated region:219-264	binding-associated region:468-602	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q93ED6	uniprotkb:P02751	intact:EBI-9826140	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q93ed6_9stre(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Tiouajni et al. (2014)	pubmed:25290767|imex:IM-23207	taxid:148942(streptococcus equi subsp. equi)|taxid:148942(Streptococcus equi subsp. equi)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9826231|imex:IM-23207-6	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:5DCQ|interpro:IPR023849|interpro:IPR013552(Fibronectin-binding, signal sequence)|mint:Q93ED6|refseq:WP_052292771.1	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.8x10^-6(molar)	2014/09/30	2025/03/31	rogid:2L9anYvFpOUkmhq8YSuzVSRvRj0148942	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:32C9E055D117A98B|rigid:2x6nyRK5fqDzM/xmh7/uOUB+SuM	false	tandem tag:?-?|binding-associated region:219-264	binding-associated region:306-602	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q93ED6	uniprotkb:P02751	intact:EBI-9826140	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q93ed6_9stre(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Tiouajni et al. (2014)	pubmed:25290767|imex:IM-23207	taxid:148942(streptococcus equi subsp. equi)|taxid:148942(Streptococcus equi subsp. equi)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9826206|imex:IM-23207-4	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:5DCQ|interpro:IPR023849|interpro:IPR013552(Fibronectin-binding, signal sequence)|mint:Q93ED6|refseq:WP_052292771.1	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:f2d|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/09/30	2025/03/31	rogid:2L9anYvFpOUkmhq8YSuzVSRvRj0148942	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:03703D489BBB8540|rigid:2x6nyRK5fqDzM/xmh7/uOUB+SuM	false	tandem tag:?-?|binding-associated region:219-264	binding-associated region:468-602	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0816""(molecular weight estimation by staining)"
uniprotkb:P02751	uniprotkb:Q93ED6	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	intact:EBI-9826140	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q93ed6_9stre(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)	"psi-mi:""MI:0053""(fluorescence polarization spectroscopy)"	Tiouajni et al. (2014)	pubmed:25290767|imex:IM-23207	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:148942(streptococcus equi subsp. equi)|taxid:148942(Streptococcus equi subsp. equi)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9826564|imex:IM-23207-8	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	rcsb pdb:5DCQ|interpro:IPR023849|interpro:IPR013552(Fibronectin-binding, signal sequence)|mint:Q93ED6|refseq:WP_052292771.1	-	-	-	figure legend:f3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.22x10^-6(molar)	2014/09/30	2025/03/25	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:2L9anYvFpOUkmhq8YSuzVSRvRj0148942	intact-crc:3EC2348D073DF840|rigid:2x6nyRK5fqDzM/xmh7/uOUB+SuM	false	binding-associated region:306-602	binding-associated region:219-264	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q93ED6	uniprotkb:P02751	intact:EBI-9826140	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839.4	psi-mi:q93ed6_9stre(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	"psi-mi:""MI:0826""(x ray scattering)"	Tiouajni et al. (2014)	pubmed:25290767|imex:IM-23207	taxid:148942(streptococcus equi subsp. equi)|taxid:148942(Streptococcus equi subsp. equi)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9826586|imex:IM-23207-9	intact-miscore:0.68	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:5DCQ|interpro:IPR023849|interpro:IPR013552(Fibronectin-binding, signal sequence)|mint:Q93ED6|refseq:WP_052292771.1	"efo:""Orphanet:84090""|efo:""Orphanet:93315""|ensembl:ENSG00000115414.21(gene)|ensembl:ENST00000354785.11(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005577""(fibrinogen complex)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0006953""(acute-phase response)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009611""(response to wounding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014850""(response to muscle activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0018149""(peptide cross-linking)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042060""(wound healing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0071635""(negative regulation of transforming growth factor beta production)|go:""GO:0072562""(blood microparticle)|rcsb pdb:2RKY|go:""GO:0150102""(negative regulation of monocyte activation)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1904237""(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|interpro:IPR050991|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|rcsb pdb:8PEQ|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9634597|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9860927|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:XP_005246463.1|dip:DIP-29547N|panther:PTHR46708(orthology-group)"	-	-	-	figure legend:t3 f7|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/09/30	2025/03/31	rogid:2L9anYvFpOUkmhq8YSuzVSRvRj0148942	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	intact-crc:1596675A5FF7FAE4|rigid:2x6nyRK5fqDzM/xmh7/uOUB+SuM	false	his tag:?-?	binding-associated region:468-602	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q5S007	uniprotkb:P00634	intact:EBI-5323863|uniprotkb:A6NJU2|uniprotkb:Q6ZS50|uniprotkb:Q8NCX9|intact:EBI-28978369|ensembl:ENSP00000298910.7	intact:EBI-552958|uniprotkb:P77801|uniprotkb:P78051|uniprotkb:Q2MC42|uniprotkb:Q47041	psi-mi:lrrk2_human(display_long)|uniprotkb:LRRK2(gene name)|psi-mi:LRRK2(display_short)|uniprotkb:PARK8(gene name synonym)|uniprotkb:Dardarin(gene name synonym)	psi-mi:ppb_ecoli(display_long)|uniprotkb:phoA(gene name)|psi-mi:phoA(display_short)|uniprotkb:b0383(locus name)|uniprotkb:JW0374(locus name)	"psi-mi:""MI:1019""(protein phosphatase assay)"	Lobbestael et al. (2013)	pubmed:23937259|imex:IM-23014	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0203""(dephosphorylation reaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-9690874|imex:IM-23014-4	intact-miscore:0.44	-	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2828""|efo:""Orphanet:411602""|dip:DIP-29684N|ensembl:ENSG00000188906.17(gene)|ensembl:ENST00000298910.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000149""(SNARE binding)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003779""(actin binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007040""(lysosome organization)|go:""GO:0007254""(JNK cascade)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0008017""(microtubule binding)|go:""GO:0008104""(protein localization)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0010955""(negative regulation of protein processing)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0014041""(regulation of neuron maturation)|go:""GO:0015631""(tubulin binding)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0016301""(kinase activity)|go:""GO:0016310""(phosphorylation)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0021756""(striatum development)|go:""GO:0021772""(olfactory bulb development)|go:""GO:0022028""(tangential migration from the subventricular zone to the olfactory bulb)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030276""(clathrin binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031344""(regulation of cell projection organization)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032473""(cytoplasmic side of mitochondrial outer membrane)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034211""(GTP-dependent protein kinase activity)|go:""GO:0034260""(negative regulation of GTPase activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035564""(regulation of kidney size)|go:""GO:0035640""(exploration behavior)|go:""GO:0035641""(locomotory exploration behavior)|go:""GO:0035751""(regulation of lysosomal lumen pH)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036479""(peroxidase inhibitor activity)|go:""GO:0039706""(co-receptor binding)|go:""GO:0040012""(regulation of locomotion)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043068""(positive regulation of programmed cell death)|go:""GO:0043195""(terminal bouton)|go:""GO:0043204""(perikaryon)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043406""(positive regulation of MAP kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044753""(amphisome)|go:""GO:0044754""(autolysosome)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0046039""(GTP metabolic process)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048312""(intracellular distribution of mitochondria)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051018""(protein kinase A binding)|go:""GO:0051646""(mitochondrion localization)|go:""GO:0051770""(obsolete positive regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0051900""(regulation of mitochondrial depolarization)|go:""GO:0051966""(regulation of synaptic transmission, glutamatergic)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0060159""(regulation of dopamine receptor signaling pathway)|go:""GO:0060161""(positive regulation of dopamine receptor signaling pathway)|go:""GO:0060628""(regulation of ER to Golgi vesicle-mediated transport)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0061001""(regulation of dendritic spine morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070585""(protein localization to mitochondrion)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0070973""(protein localization to endoplasmic reticulum exit site)|go:""GO:0071287""(cellular response to manganese ion)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090140""(regulation of mitochondrial fission)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090394""(negative regulation of excitatory postsynaptic potential)|go:""GO:0097487""(multivesicular body, internal vesicle)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099400""(caveola neck)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140058""(neuron projection arborization)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:0141161""(regulation of cAMP/PKA signal transduction)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1900244""(positive regulation of synaptic vesicle endocytosis)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902499""(positive regulation of protein autoubiquitination)|go:""GO:1902692""(regulation of neuroblast proliferation)|go:""GO:1902803""(regulation of synaptic vesicle transport)|go:""GO:1902823""(negative regulation of late endosome to lysosome transport)|go:""GO:1902902""(negative regulation of autophagosome assembly)|go:""GO:1903125""(negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation)|go:""GO:1903215""(negative regulation of protein targeting to mitochondrion)|go:""GO:1903217""(negative regulation of protein processing involved in protein targeting to mitochondrion)|go:""GO:1903351""(cellular response to dopamine)|go:""GO:1903980""(positive regulation of microglial cell activation)|go:""GO:1904713""(beta-catenin destruction complex binding)|go:""GO:1904887""(Wnt signalosome assembly)|go:""GO:1905279""(regulation of retrograde transport, endosome to Golgi)|go:""GO:1905289""(regulation of CAMKK-AMPK signaling cascade)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:1990909""(Wnt signalosome)|go:""GO:2000172""(regulation of branching morphogenesis of a nerve)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|go:""GO:2000377""(regulation of reactive oxygen species metabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020859|interpro:IPR027417|interpro:IPR032171|interpro:IPR032675|interpro:IPR036322|interpro:IPR036770|interpro:IPR051420|mint:Q5S007|rcsb pdb:2ZEJ|rcsb pdb:3D6T|rcsb pdb:5MY9|rcsb pdb:5MYC|rcsb pdb:6DLO|rcsb pdb:6DLP|rcsb pdb:6OJE|rcsb pdb:6OJF|rcsb pdb:6VNO|rcsb pdb:6VP6|rcsb pdb:6VP7|rcsb pdb:6XAF|rcsb pdb:6XR4|rcsb pdb:7LHT|rcsb pdb:7LHW|rcsb pdb:7LI3|rcsb pdb:7LI4|rcsb pdb:7THY|rcsb pdb:7THZ|rcsb pdb:8FO2|rcsb pdb:8FO7|rcsb pdb:8FO8|rcsb pdb:8FO9|rcsb pdb:8SMC|rcsb pdb:8TXZ|rcsb pdb:8TYQ|rcsb pdb:8TZB|rcsb pdb:8TZC|rcsb pdb:8TZE|rcsb pdb:8TZF|rcsb pdb:8TZG|rcsb pdb:8TZH|rcsb pdb:8U1B|rcsb pdb:8U7H|rcsb pdb:8U7L|rcsb pdb:8U8A|rcsb pdb:8U8B|rcsb pdb:8VH4|rcsb pdb:8VH5|reactome:R-HSA-8857538|refseq:NP_940980.3|panther:PTHR45752(orthology-group)"	"refseq:NP_414917.2|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004035""(alkaline phosphatase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0030613""(oxidoreductase activity, acting on phosphorus or arsenic in donors)|go:""GO:0033748""(""hydrogenase (acceptor) activity"")|go:""GO:0042597""(periplasmic space)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|rcsb pdb:1AJA|rcsb pdb:1AJB|rcsb pdb:1AJC|rcsb pdb:1AJD|rcsb pdb:1ALH|rcsb pdb:1ALI|rcsb pdb:1ALJ|rcsb pdb:1ALK|rcsb pdb:1ANI|rcsb pdb:1ANJ|rcsb pdb:1B8J|rcsb pdb:1ED8|rcsb pdb:1ED9|rcsb pdb:1ELX|rcsb pdb:1ELY|rcsb pdb:1ELZ|rcsb pdb:1EW8|rcsb pdb:1EW9|rcsb pdb:1HJK|rcsb pdb:1HQA|rcsb pdb:1KH4|rcsb pdb:1KH5|rcsb pdb:1KH7|rcsb pdb:1KH9|rcsb pdb:1KHJ|rcsb pdb:1KHK|rcsb pdb:1KHL|rcsb pdb:1KHN|rcsb pdb:1URA|rcsb pdb:1URB|rcsb pdb:1Y6V|rcsb pdb:1Y7A|rcsb pdb:2ANH|rcsb pdb:2G9Y|rcsb pdb:2GA3|rcsb pdb:2MLX|rcsb pdb:2MLY|rcsb pdb:2MLZ|rcsb pdb:3BDF|rcsb pdb:3BDG|rcsb pdb:3BDH|rcsb pdb:3CMR|rcsb pdb:3DPC|rcsb pdb:3DYC|rcsb pdb:3TG0|rcsb pdb:4KM4|rcsb pdb:4YR1|rcsb pdb:5C66|rcsb pdb:5GAD|rcsb pdb:5GAF|rcsb pdb:5GAG|rcsb pdb:5GAH|rcsb pdb:5JTL|rcsb pdb:5JTM|rcsb pdb:5JTN|rcsb pdb:5JTO|rcsb pdb:5JTP|rcsb pdb:5TPQ|rcsb pdb:6PPT|rcsb pdb:6PQ2|rcsb pdb:6PQE|rcsb pdb:6PQM|rcsb pdb:6PRI|rcsb pdb:6PRJ|rcsb pdb:6PRQ|rcsb pdb:6PSI|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|refseq:WP_000814403.1|dip:DIP-10496N|panther:PTHR11596(orthology-group)"	"go:""GO:0006470""(protein dephosphorylation)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)"	-	-	figure legend:Figure 1|comment:positive control|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Affinomics - Interactions curated for the Affinomics consortium.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/08/11	2025/03/31	rogid:5ZNs+6rMb4Ifz0nBk6RgYmaCFsM9606	rogid:RWPdGs8xyEdVg8pMi5LMyyqX0ZA83333	intact-crc:7EA2A866A14BD39A|rigid:i1c9hPeBerYrdo7YPUoVF+DRSFE	false	32p radiolabel:?-?|phosphorylated residue:?-?|flag tag:n-n	-	-	-	"psi-mi:""MI:0821""(molecular weight estimation by autoradiography)"	"psi-mi:""MI:0821""(molecular weight estimation by autoradiography)"
uniprotkb:Q5S007	uniprotkb:P00634	intact:EBI-5323863|uniprotkb:A6NJU2|uniprotkb:Q6ZS50|uniprotkb:Q8NCX9|intact:EBI-28978369|ensembl:ENSP00000298910.7	intact:EBI-552958|uniprotkb:P77801|uniprotkb:P78051|uniprotkb:Q2MC42|uniprotkb:Q47041	psi-mi:lrrk2_human(display_long)|uniprotkb:LRRK2(gene name)|psi-mi:LRRK2(display_short)|uniprotkb:PARK8(gene name synonym)|uniprotkb:Dardarin(gene name synonym)	psi-mi:ppb_ecoli(display_long)|uniprotkb:phoA(gene name)|psi-mi:phoA(display_short)|uniprotkb:b0383(locus name)|uniprotkb:JW0374(locus name)	"psi-mi:""MI:1019""(protein phosphatase assay)"	Lobbestael et al. (2013)	pubmed:23937259|imex:IM-23014	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83333(ecoli)|taxid:83333(""Escherichia coli (strain K12)"")"	"psi-mi:""MI:0203""(dephosphorylation reaction)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-9690852|imex:IM-23014-3	intact-miscore:0.44	-	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2828""|efo:""Orphanet:411602""|dip:DIP-29684N|ensembl:ENSG00000188906.17(gene)|ensembl:ENST00000298910.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000149""(SNARE binding)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003779""(actin binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007040""(lysosome organization)|go:""GO:0007254""(JNK cascade)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0008017""(microtubule binding)|go:""GO:0008104""(protein localization)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0010955""(negative regulation of protein processing)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0014041""(regulation of neuron maturation)|go:""GO:0015631""(tubulin binding)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0016301""(kinase activity)|go:""GO:0016310""(phosphorylation)|go:""GO:0017075""(syntaxin-1 binding)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0021756""(striatum development)|go:""GO:0021772""(olfactory bulb development)|go:""GO:0022028""(tangential migration from the subventricular zone to the olfactory bulb)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030276""(clathrin binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031344""(regulation of cell projection organization)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032473""(cytoplasmic side of mitochondrial outer membrane)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034211""(GTP-dependent protein kinase activity)|go:""GO:0034260""(negative regulation of GTPase activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035564""(regulation of kidney size)|go:""GO:0035640""(exploration behavior)|go:""GO:0035641""(locomotory exploration behavior)|go:""GO:0035751""(regulation of lysosomal lumen pH)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036479""(peroxidase inhibitor activity)|go:""GO:0039706""(co-receptor binding)|go:""GO:0040012""(regulation of locomotion)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043068""(positive regulation of programmed cell death)|go:""GO:0043195""(terminal bouton)|go:""GO:0043204""(perikaryon)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043406""(positive regulation of MAP kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044753""(amphisome)|go:""GO:0044754""(autolysosome)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0046039""(GTP metabolic process)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048312""(intracellular distribution of mitochondria)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051018""(protein kinase A binding)|go:""GO:0051646""(mitochondrion localization)|go:""GO:0051770""(obsolete positive regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0051900""(regulation of mitochondrial depolarization)|go:""GO:0051966""(regulation of synaptic transmission, glutamatergic)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060079""(excitatory postsynaptic potential)|go:""GO:0060159""(regulation of dopamine receptor signaling pathway)|go:""GO:0060161""(positive regulation of dopamine receptor signaling pathway)|go:""GO:0060628""(regulation of ER to Golgi vesicle-mediated transport)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0061001""(regulation of dendritic spine morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070585""(protein localization to mitochondrion)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0070973""(protein localization to endoplasmic reticulum exit site)|go:""GO:0071287""(cellular response to manganese ion)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090140""(regulation of mitochondrial fission)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090394""(negative regulation of excitatory postsynaptic potential)|go:""GO:0097487""(multivesicular body, internal vesicle)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099400""(caveola neck)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140058""(neuron projection arborization)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:0141161""(regulation of cAMP/PKA signal transduction)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1900244""(positive regulation of synaptic vesicle endocytosis)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1902499""(positive regulation of protein autoubiquitination)|go:""GO:1902692""(regulation of neuroblast proliferation)|go:""GO:1902803""(regulation of synaptic vesicle transport)|go:""GO:1902823""(negative regulation of late endosome to lysosome transport)|go:""GO:1902902""(negative regulation of autophagosome assembly)|go:""GO:1903125""(negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation)|go:""GO:1903215""(negative regulation of protein targeting to mitochondrion)|go:""GO:1903217""(negative regulation of protein processing involved in protein targeting to mitochondrion)|go:""GO:1903351""(cellular response to dopamine)|go:""GO:1903980""(positive regulation of microglial cell activation)|go:""GO:1904713""(beta-catenin destruction complex binding)|go:""GO:1904887""(Wnt signalosome assembly)|go:""GO:1905279""(regulation of retrograde transport, endosome to Golgi)|go:""GO:1905289""(regulation of CAMKK-AMPK signaling cascade)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990606""(membrane scission GTPase motor activity)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:1990909""(Wnt signalosome)|go:""GO:2000172""(regulation of branching morphogenesis of a nerve)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|go:""GO:2000377""(regulation of reactive oxygen species metabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020859|interpro:IPR027417|interpro:IPR032171|interpro:IPR032675|interpro:IPR036322|interpro:IPR036770|interpro:IPR051420|mint:Q5S007|rcsb pdb:2ZEJ|rcsb pdb:3D6T|rcsb pdb:5MY9|rcsb pdb:5MYC|rcsb pdb:6DLO|rcsb pdb:6DLP|rcsb pdb:6OJE|rcsb pdb:6OJF|rcsb pdb:6VNO|rcsb pdb:6VP6|rcsb pdb:6VP7|rcsb pdb:6XAF|rcsb pdb:6XR4|rcsb pdb:7LHT|rcsb pdb:7LHW|rcsb pdb:7LI3|rcsb pdb:7LI4|rcsb pdb:7THY|rcsb pdb:7THZ|rcsb pdb:8FO2|rcsb pdb:8FO7|rcsb pdb:8FO8|rcsb pdb:8FO9|rcsb pdb:8SMC|rcsb pdb:8TXZ|rcsb pdb:8TYQ|rcsb pdb:8TZB|rcsb pdb:8TZC|rcsb pdb:8TZE|rcsb pdb:8TZF|rcsb pdb:8TZG|rcsb pdb:8TZH|rcsb pdb:8U1B|rcsb pdb:8U7H|rcsb pdb:8U7L|rcsb pdb:8U8A|rcsb pdb:8U8B|rcsb pdb:8VH4|rcsb pdb:8VH5|reactome:R-HSA-8857538|refseq:NP_940980.3|panther:PTHR45752(orthology-group)"	"refseq:NP_414917.2|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004035""(alkaline phosphatase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0030613""(oxidoreductase activity, acting on phosphorus or arsenic in donors)|go:""GO:0033748""(""hydrogenase (acceptor) activity"")|go:""GO:0042597""(periplasmic space)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|rcsb pdb:1AJA|rcsb pdb:1AJB|rcsb pdb:1AJC|rcsb pdb:1AJD|rcsb pdb:1ALH|rcsb pdb:1ALI|rcsb pdb:1ALJ|rcsb pdb:1ALK|rcsb pdb:1ANI|rcsb pdb:1ANJ|rcsb pdb:1B8J|rcsb pdb:1ED8|rcsb pdb:1ED9|rcsb pdb:1ELX|rcsb pdb:1ELY|rcsb pdb:1ELZ|rcsb pdb:1EW8|rcsb pdb:1EW9|rcsb pdb:1HJK|rcsb pdb:1HQA|rcsb pdb:1KH4|rcsb pdb:1KH5|rcsb pdb:1KH7|rcsb pdb:1KH9|rcsb pdb:1KHJ|rcsb pdb:1KHK|rcsb pdb:1KHL|rcsb pdb:1KHN|rcsb pdb:1URA|rcsb pdb:1URB|rcsb pdb:1Y6V|rcsb pdb:1Y7A|rcsb pdb:2ANH|rcsb pdb:2G9Y|rcsb pdb:2GA3|rcsb pdb:2MLX|rcsb pdb:2MLY|rcsb pdb:2MLZ|rcsb pdb:3BDF|rcsb pdb:3BDG|rcsb pdb:3BDH|rcsb pdb:3CMR|rcsb pdb:3DPC|rcsb pdb:3DYC|rcsb pdb:3TG0|rcsb pdb:4KM4|rcsb pdb:4YR1|rcsb pdb:5C66|rcsb pdb:5GAD|rcsb pdb:5GAF|rcsb pdb:5GAG|rcsb pdb:5GAH|rcsb pdb:5JTL|rcsb pdb:5JTM|rcsb pdb:5JTN|rcsb pdb:5JTO|rcsb pdb:5JTP|rcsb pdb:5TPQ|rcsb pdb:6PPT|rcsb pdb:6PQ2|rcsb pdb:6PQE|rcsb pdb:6PQM|rcsb pdb:6PRI|rcsb pdb:6PRJ|rcsb pdb:6PRQ|rcsb pdb:6PSI|rcsb pdb:7JMM|rcsb pdb:7JN8|rcsb pdb:7JN9|rcsb pdb:7JNE|rcsb pdb:7N6J|rcsb pdb:7N6K|rcsb pdb:7N6L|rcsb pdb:7N6M|refseq:WP_000814403.1|dip:DIP-10496N|panther:PTHR11596(orthology-group)"	"go:""GO:0006470""(protein dephosphorylation)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)"	-	-	figure legend:Figure 1|comment:positive control|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|curation depth:imex curation|full coverage:Only protein-protein interactions|dataset:Affinomics - Interactions curated for the Affinomics consortium.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/08/11	2025/03/31	rogid:5ZNs+6rMb4Ifz0nBk6RgYmaCFsM9606	rogid:RWPdGs8xyEdVg8pMi5LMyyqX0ZA83333	intact-crc:A9188623D0817FE6|rigid:i1c9hPeBerYrdo7YPUoVF+DRSFE	false	32p radiolabel:?-?|O-phospho-L-serine:973-973|O-phospho-L-serine:935-935|O-phospho-L-serine:910-910|O-phospho-L-serine:955-955|flag tag:n-n	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P24071	uniprotkb:A8E1U6	intact:EBI-1036488|uniprotkb:Q13603|uniprotkb:Q13604|uniprotkb:Q15727|uniprotkb:Q15728|uniprotkb:Q92590|uniprotkb:Q1AJL7|uniprotkb:Q1AJL8|uniprotkb:Q1AJL9|uniprotkb:Q53X38|uniprotkb:Q92587|uniprotkb:Q92588|uniprotkb:Q92592|uniprotkb:Q92593|uniprotkb:Q9UEK0|uniprotkb:Q53X39|ensembl:ENSP00000347714.3|ensembl:ENSP00000478465.1|ensembl:ENSP00000479738.1|ensembl:ENSP00000481195.1|ensembl:ENSP00000481502.1|ensembl:ENSP00000482334.1|ensembl:ENSP00000482623.1|ensembl:ENSP00000482807.1|ensembl:ENSP00000483099.1|ensembl:ENSP00000492230.1|ensembl:ENSP00000492447.1|ensembl:ENSP00000492529.2	intact:EBI-6401400	psi-mi:fcar_human(display_long)|uniprotkb:FCAR(gene name)|psi-mi:FCAR(display_short)|uniprotkb:CD89(gene name synonym)	psi-mi:a8e1u6_staau(display_long)|uniprotkb:sl11(gene name)|psi-mi:sl11(display_short)	"psi-mi:""MI:0047""(far western blotting)"	Chung et al. (2007)	pubmed:18045383|imex:IM-18162	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6401409|mpidb:MPIDB-INT-1074|imex:IM-18162-2	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001991.1|refseq:NP_579803.1|refseq:NP_579805.1|refseq:NP_579806.1|refseq:NP_579807.1|refseq:NP_579808.1|refseq:NP_579811.1|refseq:NP_579812.1|ensembl:ENSG00000186431.19(gene)|ensembl:ENSG00000273738.4(gene)|ensembl:ENSG00000274580.4(gene)|ensembl:ENSG00000275136.4(gene)|ensembl:ENSG00000275269.4(gene)|ensembl:ENSG00000275564.4(gene)|ensembl:ENSG00000275970.4(gene)|ensembl:ENSG00000276858.4(gene)|ensembl:ENSG00000276985.4(gene)|ensembl:ENSG00000283750.3(gene)|ensembl:ENSG00000284061.2(gene)|ensembl:ENST00000355524.8(transcript)|ensembl:ENST00000613199.4(transcript)|ensembl:ENST00000614226.4(transcript)|ensembl:ENST00000615829.4(transcript)|ensembl:ENST00000619385.4(transcript)|ensembl:ENST00000620801.4(transcript)|ensembl:ENST00000621702.4(transcript)|ensembl:ENST00000622157.4(transcript)|ensembl:ENST00000622737.4(transcript)|ensembl:ENST00000638212.2(transcript)|ensembl:ENST00000640025.2(transcript)|ensembl:ENST00000640582.2(transcript)|go:""GO:0002446""(neutrophil mediated immunity)|go:""GO:0002764""(immune response-regulating signaling pathway)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0019766""(IgA receptor activity)|go:""GO:0019862""(IgA binding)|go:""GO:0033031""(positive regulation of neutrophil apoptotic process)|go:""GO:0035457""(cellular response to interferon-alpha)|go:""GO:0035579""(specific granule membrane)|go:""GO:0038093""(Fc receptor signaling pathway)|go:""GO:0042119""(neutrophil activation)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097011""(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050412|rcsb pdb:1OVZ|rcsb pdb:1OW0|rcsb pdb:1UCT|rcsb pdb:8SKU|reactome:R-HSA-6798695|panther:PTHR11738(orthology-group)"	"go:""GO:0005576""(extracellular region)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)"	-	-	-	figure legend:Fig. 1B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2024/11/14	rogid:ycl94oh6X+RBbqjJyhU44bOz+d89606	rogid:+6aD4MOf/k9A8EQ2/iaXFXhSKiI1280	intact-crc:9F9D302231EB5276|rigid:KP8v6hPtE//WF+QuAAJrnjx6uWU	false	his tag:c-c|sufficient binding region:22-229|biotin tag:c-c	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q7BG35	uniprotkb:P06731	intact:EBI-6471155	intact:EBI-3914938|uniprotkb:H9KVA7|intact:EBI-28983305|ensembl:ENSP00000221992.5|ensembl:ENSP00000385072.1|ensembl:ENSP00000482303.1	psi-mi:q7bg35_ecolx(display_long)|uniprotkb:draE(gene name)|psi-mi:draE(display_short)	psi-mi:ceam5_human(display_long)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 5(gene name synonym)|uniprotkb:CEACAM5(gene name)|psi-mi:CEACAM5(display_short)|uniprotkb:Carcinoembryonic antigen(gene name synonym)|uniprotkb:CEA(gene name synonym)|uniprotkb:Meconium antigen 100(gene name synonym)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Korotkova et al. (2008)	pubmed:18086185|imex:IM-18169	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6471149|imex:IM-18169-8|mpidb:MPIDB-INT-1046|wwpdb:2qst	intact-miscore:0.44	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR021020|interpro:IPR006713(Adhesin, Dr-family)|interpro:IPR008966(Adhesion, bacterial)|refseq:WP_063269203.1|interpro:IPR037028	"refseq:NP_001278413.1|refseq:NP_001295327.1|refseq:NP_004354.3|dip:DIP-57769N|ensembl:ENSG00000105388.17(gene)|ensembl:ENST00000221992.11(transcript)|ensembl:ENST00000405816.5(transcript)|ensembl:ENST00000617332.4(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0009986""(cell surface)|go:""GO:0010832""(negative regulation of myotube differentiation)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0034109""(homotypic cell-cell adhesion)|go:""GO:0034235""(GPI anchor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098552""(side of membrane)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P06731|rcsb pdb:1E07|rcsb pdb:2QSQ|rcsb pdb:2QST|rcsb pdb:2VER|rcsb pdb:8BW0|reactome:R-HSA-163125|reactome:R-HSA-202733|refseq:XP_016881634.1|panther:PTHR44337(orthology-group)"	-	-	-	figure legend:Fig4C-E|agonist:DTT|comment:DraE appears to disrupt N-CEA dimers prior to binding to the resulting monomer.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2024/11/14	rogid:R3CuDQrzpbbcOhfCro/oLM7c/AY562	rogid:6HjZaCVuVCR0Mz6dFxOAHzhOqII9606	intact-crc:B6C96B20CB1E968F|rigid:MkmQ5EsHbBjVZErVpIRT9aCLD3M	false	-	mutation:73-73|sufficient binding region:34-144	2	2	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P06731	uniprotkb:Q57254	intact:EBI-3914938|uniprotkb:H9KVA7|intact:EBI-28983305|ensembl:ENSP00000221992.5|ensembl:ENSP00000385072.1|ensembl:ENSP00000482303.1	intact:EBI-6401630	psi-mi:ceam5_human(display_long)|uniprotkb:Carcinoembryonic antigen-related cell adhesion molecule 5(gene name synonym)|uniprotkb:CEACAM5(gene name)|psi-mi:CEACAM5(display_short)|uniprotkb:Carcinoembryonic antigen(gene name synonym)|uniprotkb:CEA(gene name synonym)|uniprotkb:Meconium antigen 100(gene name synonym)	psi-mi:afae3_ecolx(display_long)|uniprotkb:afaE3(gene name)|psi-mi:afaE3(display_short)|uniprotkb:afaE-3(gene name synonym)	"psi-mi:""MI:0077""(nuclear magnetic resonance)"	Korotkova et al. (2008)	pubmed:18086185|imex:IM-18169	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:562(ecolx)|taxid:562(Escherichia coli)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6401635|mpidb:MPIDB-INT-1045|imex:IM-18169-2	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001278413.1|refseq:NP_001295327.1|refseq:NP_004354.3|dip:DIP-57769N|ensembl:ENSG00000105388.17(gene)|ensembl:ENST00000221992.11(transcript)|ensembl:ENST00000405816.5(transcript)|ensembl:ENST00000617332.4(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0009986""(cell surface)|go:""GO:0010832""(negative regulation of myotube differentiation)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0034109""(homotypic cell-cell adhesion)|go:""GO:0034235""(GPI anchor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098552""(side of membrane)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050831|mint:P06731|rcsb pdb:1E07|rcsb pdb:2QSQ|rcsb pdb:2QST|rcsb pdb:2VER|rcsb pdb:8BW0|reactome:R-HSA-163125|reactome:R-HSA-202733|refseq:XP_016881634.1|panther:PTHR44337(orthology-group)"	"go:""GO:0009289""(pilus)|interpro:IPR006713(Adhesin, Dr-family)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR021020|rcsb pdb:1RXL|rcsb pdb:1USZ|rcsb pdb:1UT2|rcsb pdb:2IXQ|rcsb pdb:2VER|interpro:IPR037028"	-	-	-	figure legend:Table 4|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2025/03/31	rogid:6HjZaCVuVCR0Mz6dFxOAHzhOqII9606	rogid:xkbQEBFFX5H/IiogDqNzwXKU3sw562	intact-crc:429C14BD820BE634|rigid:lbmysjekvgSntOIVQwqHdV3u5AQ	false	mutation:52-52|mutation:54-54	15n label:?-?	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P08603	uniprotkb:P16946	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	intact:EBI-6403567	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	psi-mi:mx_strp9(display_long)|uniprotkb:ennX(gene name)|psi-mi:ennX(display_short)	"psi-mi:""MI:0400""(affinity technology)"	Haapasalo et al. (2008)	pubmed:18627465|imex:IM-18214	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:301452(strp9)|taxid:301452(Streptococcus pyogenes serotype M49)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6403574|mpidb:MPIDB-INT-622|imex:IM-18214-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006909""(phagocytosis)|interpro:IPR003345(M protein repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR019950|interpro:IPR049895|interpro:IPR049896|interpro:IPR019931"	-	-	-	figure legend:Fig. 3-6|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2025/03/31	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	rogid:99hWfG/hA/360q9HK651Xvs4gTY301452	intact-crc:7FB2A7BF170F2C76|rigid:FZZs6uOsvimZeBOYDv53ogbbPzs	false	mutation decreasing interaction strength:402-402|sufficient binding region:265..265-444..444	125i radiolabel:?-?	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P16946	uniprotkb:P08603	intact:EBI-6403567	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399.4	psi-mi:mx_strp9(display_long)|uniprotkb:ennX(gene name)|psi-mi:ennX(display_short)	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	"psi-mi:""MI:0400""(affinity technology)"	Haapasalo et al. (2008)	pubmed:18627465|imex:IM-18214	taxid:301452(strp9)|taxid:301452(Streptococcus pyogenes serotype M49)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6403579|mpidb:MPIDB-INT-621|imex:IM-18214-2	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0006909""(phagocytosis)|interpro:IPR003345(M protein repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR019950|interpro:IPR049895|interpro:IPR049896|interpro:IPR019931"	"efo:""Orphanet:200421""|efo:""Orphanet:244242""|efo:""Orphanet:244275""|efo:""Orphanet:329903""|efo:""Orphanet:544472""|efo:""Orphanet:75376""|efo:""Orphanet:93571""|ensembl:ENSG00000000971.17(gene)|ensembl:ENST00000367429.9(transcript)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006956""(complement activation)|go:""GO:0006957""(complement activation, alternative pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0030451""(regulation of complement activation, alternative pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0106139""(symbiont cell surface)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR051503|mint:P08603|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:5WTB|rcsb pdb:6ATG|rcsb pdb:6ZH1|rcsb pdb:7WKI|rcsb pdb:7ZJM|reactome:R-HSA-977606|refseq:NP_000177.2|dip:DIP-38303N|panther:PTHR45785(orthology-group)"	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2025/01/22	rogid:99hWfG/hA/360q9HK651Xvs4gTY301452	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	intact-crc:EB4F9D55310BFF59|rigid:FZZs6uOsvimZeBOYDv53ogbbPzs	false	-	-	-	-	"psi-mi:""MI:0866""(tag visualisation)"	"psi-mi:""MI:0866""(tag visualisation)"
uniprotkb:P09486	uniprotkb:Q2TV77	intact:EBI-2800983|uniprotkb:Q6IBK4|uniprotkb:D3DQH9|ensembl:ENSP00000231061.4	intact:EBI-6405263	psi-mi:sprc_human(display_long)|uniprotkb:ON(gene name synonym)|uniprotkb:Basement-membrane protein 40(gene name synonym)|uniprotkb:Osteonectin(gene name synonym)|uniprotkb:Secreted protein acidic and rich in cysteine(gene name synonym)|uniprotkb:SPARC(gene name)|psi-mi:SPARC(display_short)	psi-mi:q2tv77_finma(display_long)|uniprotkb:faf(gene name)|psi-mi:faf(display_short)	"psi-mi:""MI:0047""(far western blotting)"	Frick et al. (2008)	pubmed:18808384|imex:IM-18235	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1260(pepma)|taxid:1260(Peptostreptococcus magnus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6405596|imex:IM-18235-7|mpidb:MPIDB-INT-616	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000113140.11(gene)|ensembl:ENST00000231061.9(transcript)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031092""(platelet alpha granule membrane)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048752""(semicircular canal morphogenesis)|go:""GO:0050807""(regulation of synapse organization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071682""(endocytic vesicle lumen)|interpro:IPR001999(Osteonectin-like, conserved site)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|interpro:IPR037641|mint:P09486|rcsb pdb:1BMO|rcsb pdb:1NUB|rcsb pdb:1SRA|rcsb pdb:2V53|reactome:R-HSA-114608|reactome:R-HSA-1251985|reactome:R-HSA-3000178|reactome:R-HSA-3000497|refseq:NP_001296372.1|refseq:NP_001296373.1|refseq:NP_003109.1|dip:DIP-46426N|efo:""Orphanet:216820""|panther:PTHR13866(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033764|interpro:IPR019931"	-	-	-	figure legend:Fig. 6|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.3x10^-9(molar)	2012/11/30	2025/03/31	rogid:AG+FZo/KK2xdMFSEIgTbgZ2AVJc9606	rogid:x26dbTkLnV/GAmJv6yxOVNEBE6Q1260	intact-crc:92D5730ECDCF0C08|rigid:LQghCovuyvuFy+AxBONG529rx54	false	125i radiolabel:?-?	sufficient binding region:239-616	-	-	"psi-mi:""MI:0833""(autoradiography)"	"psi-mi:""MI:0833""(autoradiography)"
uniprotkb:Q2TV77	uniprotkb:P09486	intact:EBI-6405263	intact:EBI-2800983|uniprotkb:Q6IBK4|uniprotkb:D3DQH9|ensembl:ENSP00000231061.4	psi-mi:q2tv77_finma(display_long)|uniprotkb:faf(gene name)|psi-mi:faf(display_short)	psi-mi:sprc_human(display_long)|uniprotkb:ON(gene name synonym)|uniprotkb:Basement-membrane protein 40(gene name synonym)|uniprotkb:Osteonectin(gene name synonym)|uniprotkb:Secreted protein acidic and rich in cysteine(gene name synonym)|uniprotkb:SPARC(gene name)|psi-mi:SPARC(display_short)	"psi-mi:""MI:0040""(electron microscopy)"	Frick et al. (2008)	pubmed:18808384|imex:IM-18235	taxid:1260(pepma)|taxid:1260(Peptostreptococcus magnus)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6405734|imex:IM-18235-9|mpidb:MPIDB-INT-616	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033764|interpro:IPR019931"	"ensembl:ENSG00000113140.11(gene)|ensembl:ENST00000231061.9(transcript)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031092""(platelet alpha granule membrane)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048752""(semicircular canal morphogenesis)|go:""GO:0050807""(regulation of synapse organization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071682""(endocytic vesicle lumen)|interpro:IPR001999(Osteonectin-like, conserved site)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|interpro:IPR037641|mint:P09486|rcsb pdb:1BMO|rcsb pdb:1NUB|rcsb pdb:1SRA|rcsb pdb:2V53|reactome:R-HSA-114608|reactome:R-HSA-1251985|reactome:R-HSA-3000178|reactome:R-HSA-3000497|refseq:NP_001296372.1|refseq:NP_001296373.1|refseq:NP_003109.1|dip:DIP-46426N|efo:""Orphanet:216820""|panther:PTHR13866(orthology-group)"	-	-	-	figure legend:Fig. 6C|comment:GST tag used to locate the N-terminus of the molecule, BM40 could then be seen to bind to the C-terminus.|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2025/02/28	rogid:x26dbTkLnV/GAmJv6yxOVNEBE6Q1260	rogid:AG+FZo/KK2xdMFSEIgTbgZ2AVJc9606	intact-crc:0433DE09EABBC277|rigid:LQghCovuyvuFy+AxBONG529rx54	false	glutathione s tranferase tag:n-n	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P09486	uniprotkb:Q2TV77	intact:EBI-2800983|uniprotkb:Q6IBK4|uniprotkb:D3DQH9|ensembl:ENSP00000231061.4	intact:EBI-6405263	psi-mi:sprc_human(display_long)|uniprotkb:ON(gene name synonym)|uniprotkb:Basement-membrane protein 40(gene name synonym)|uniprotkb:Osteonectin(gene name synonym)|uniprotkb:Secreted protein acidic and rich in cysteine(gene name synonym)|uniprotkb:SPARC(gene name)|psi-mi:SPARC(display_short)	psi-mi:q2tv77_finma(display_long)|uniprotkb:faf(gene name)|psi-mi:faf(display_short)	"psi-mi:""MI:0040""(electron microscopy)"	Frick et al. (2008)	pubmed:18808384|imex:IM-18235	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1260(pepma)|taxid:1260(Peptostreptococcus magnus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6405689|imex:IM-18235-8|mpidb:MPIDB-INT-616	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000113140.11(gene)|ensembl:ENST00000231061.9(transcript)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031092""(platelet alpha granule membrane)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048752""(semicircular canal morphogenesis)|go:""GO:0050807""(regulation of synapse organization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071682""(endocytic vesicle lumen)|interpro:IPR001999(Osteonectin-like, conserved site)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|interpro:IPR037641|mint:P09486|rcsb pdb:1BMO|rcsb pdb:1NUB|rcsb pdb:1SRA|rcsb pdb:2V53|reactome:R-HSA-114608|reactome:R-HSA-1251985|reactome:R-HSA-3000178|reactome:R-HSA-3000497|refseq:NP_001296372.1|refseq:NP_001296373.1|refseq:NP_003109.1|dip:DIP-46426N|efo:""Orphanet:216820""|panther:PTHR13866(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033764|interpro:IPR019931"	-	-	-	figure legend:Fig. 6C|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2025/02/28	rogid:AG+FZo/KK2xdMFSEIgTbgZ2AVJc9606	rogid:x26dbTkLnV/GAmJv6yxOVNEBE6Q1260	intact-crc:858CFE7851017255|rigid:LQghCovuyvuFy+AxBONG529rx54	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P09486	uniprotkb:Q2TV77	intact:EBI-2800983|uniprotkb:Q6IBK4|uniprotkb:D3DQH9|ensembl:ENSP00000231061.4	intact:EBI-6405263	psi-mi:sprc_human(display_long)|uniprotkb:ON(gene name synonym)|uniprotkb:Basement-membrane protein 40(gene name synonym)|uniprotkb:Osteonectin(gene name synonym)|uniprotkb:Secreted protein acidic and rich in cysteine(gene name synonym)|uniprotkb:SPARC(gene name)|psi-mi:SPARC(display_short)	psi-mi:q2tv77_finma(display_long)|uniprotkb:faf(gene name)|psi-mi:faf(display_short)	"psi-mi:""MI:0107""(surface plasmon resonance)"	Frick et al. (2008)	pubmed:18808384|imex:IM-18235	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1260(pepma)|taxid:1260(Peptostreptococcus magnus)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6404524|mpidb:MPIDB-INT-616|imex:IM-18235-5	intact-miscore:0.60	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000113140.11(gene)|ensembl:ENST00000231061.9(transcript)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031092""(platelet alpha granule membrane)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048752""(semicircular canal morphogenesis)|go:""GO:0050807""(regulation of synapse organization)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071682""(endocytic vesicle lumen)|interpro:IPR001999(Osteonectin-like, conserved site)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|interpro:IPR037641|mint:P09486|rcsb pdb:1BMO|rcsb pdb:1NUB|rcsb pdb:1SRA|rcsb pdb:2V53|reactome:R-HSA-114608|reactome:R-HSA-1251985|reactome:R-HSA-3000178|reactome:R-HSA-3000497|refseq:NP_001296372.1|refseq:NP_001296373.1|refseq:NP_003109.1|dip:DIP-46426N|efo:""Orphanet:216820""|panther:PTHR13866(orthology-group)"	"go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033764|interpro:IPR019931"	-	-	-	figure legend:Fig. 6|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.3x10^-9(molar)	2012/11/30	2025/02/28	rogid:AG+FZo/KK2xdMFSEIgTbgZ2AVJc9606	rogid:x26dbTkLnV/GAmJv6yxOVNEBE6Q1260	intact-crc:CD19A5AF3991DBA0|rigid:LQghCovuyvuFy+AxBONG529rx54	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q6XW12	uniprotkb:P06400	intact:EBI-6405381	intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163.4	psi-mi:q6xw12_shifl(display_long)|uniprotkb:ospB(gene name)|psi-mi:ospB(display_short)	psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Zurawski et al. (2009)	pubmed:19017275|imex:IM-18243	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6405385|mpidb:MPIDB-INT-1131|imex:IM-18243-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001046942.1	"ensembl:ENSG00000139687.17(gene)|ensembl:ENST00000267163.6(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001894""(tissue homeostasis)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016605""(PML body)|go:""GO:0019900""(kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031134""(sister chromatid biorientation)|go:""GO:0031175""(neuron projection development)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034088""(maintenance of mitotic sister chromatid cohesion)|go:""GO:0034349""(glial cell apoptotic process)|go:""GO:0035189""(Rb-E2F complex)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0042551""(neuron maturation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043353""(enucleate erythrocyte differentiation)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043550""(regulation of lipid kinase activity)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0045842""(positive regulation of mitotic metaphase/anaphase transition)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048565""(digestive tract development)|go:""GO:0048667""(cell morphogenesis involved in neuron differentiation)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051276""(chromosome organization)|go:""GO:0051301""(cell division)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0061793""(chromatin lock complex)|go:""GO:0071459""(protein localization to chromosome, centromeric region)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071901""(negative regulation of protein serine/threonine kinase activity)|go:""GO:0090230""(regulation of centromere complex assembly)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902948""(negative regulation of tau-protein kinase activity)|go:""GO:1903055""(positive regulation of extracellular matrix organization)|go:""GO:1903944""(negative regulation of hepatocyte apoptotic process)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904761""(negative regulation of myofibroblast differentiation)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000679""(positive regulation of transcription regulatory region DNA binding)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|reactome:R-HSA-9725371|reactome:R-HSA-9841922|refseq:NP_000312.2|efo:""Orphanet:1587""|efo:""Orphanet:357027""|efo:""Orphanet:357034""|efo:""Orphanet:668""|efo:""Orphanet:70573""|dip:DIP-582N|panther:PTHR13742(orthology-group)|ensembl:ENSP00000267163.4"	-	-	-	figure legend:Fig 8A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2025/03/31	rogid:7wEe1b1KaVJ55NETthGmE41+13c623	rogid:xidCNX96KlQzu160polvT61k4Zw9606	intact-crc:3C32F17BE96D9558|rigid:GxUb12/oINodn23JpVZmscUz23s	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q8VSP9	uniprotkb:P06400	intact:EBI-6506625|uniprotkb:Q2ET10|uniprotkb:Q2ET14|uniprotkb:Q6XW10|uniprotkb:Q7BEG0|uniprotkb:Q99Q87	intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163.4	psi-mi:ospf_shifl(display_long)|uniprotkb:ospF(gene name)|psi-mi:ospF(display_short)|uniprotkb:mkaD(gene name synonym)|uniprotkb:Effector protein OspF(gene name synonym)|uniprotkb:pWR501_0013(orf name)|uniprotkb:SFLP011(orf name)|uniprotkb:CP0010(locus name)	psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Zurawski et al. (2009)	pubmed:19017275|imex:IM-18243	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0407""(direct interaction)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6405392|mpidb:MPIDB-INT-227|imex:IM-18243-2	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|refseq:NP_858143.1|refseq:YP_006960239.1|refseq:WP_001121867.1|interpro:IPR038498|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|rcsb pdb:3I0U|refseq:WP_010921598.1|mint:Q8VSP9"	"ensembl:ENSG00000139687.17(gene)|ensembl:ENST00000267163.6(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001894""(tissue homeostasis)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016605""(PML body)|go:""GO:0019900""(kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031134""(sister chromatid biorientation)|go:""GO:0031175""(neuron projection development)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034088""(maintenance of mitotic sister chromatid cohesion)|go:""GO:0034349""(glial cell apoptotic process)|go:""GO:0035189""(Rb-E2F complex)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0042551""(neuron maturation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043353""(enucleate erythrocyte differentiation)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043550""(regulation of lipid kinase activity)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0045842""(positive regulation of mitotic metaphase/anaphase transition)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048565""(digestive tract development)|go:""GO:0048667""(cell morphogenesis involved in neuron differentiation)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051276""(chromosome organization)|go:""GO:0051301""(cell division)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0061793""(chromatin lock complex)|go:""GO:0071459""(protein localization to chromosome, centromeric region)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071901""(negative regulation of protein serine/threonine kinase activity)|go:""GO:0090230""(regulation of centromere complex assembly)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902948""(negative regulation of tau-protein kinase activity)|go:""GO:1903055""(positive regulation of extracellular matrix organization)|go:""GO:1903944""(negative regulation of hepatocyte apoptotic process)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904761""(negative regulation of myofibroblast differentiation)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000679""(positive regulation of transcription regulatory region DNA binding)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|reactome:R-HSA-9725371|reactome:R-HSA-9841922|refseq:NP_000312.2|efo:""Orphanet:1587""|efo:""Orphanet:357027""|efo:""Orphanet:357034""|efo:""Orphanet:668""|efo:""Orphanet:70573""|dip:DIP-582N|panther:PTHR13742(orthology-group)|ensembl:ENSP00000267163.4"	-	-	-	figure legend:Fig. 8B|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2025/03/31	rogid:mSCbX2cDlV97OQC/v4kEJtqiOIU623	rogid:xidCNX96KlQzu160polvT61k4Zw9606	intact-crc:AFA591787C91AAA9|rigid:4NKN/OKB6d0tHnBxkuuZT3QQd2s	false	mutation decreasing interaction strength:178-178,180-180,182-182|sufficient binding region:152-239|glutathione s tranferase tag:?-?	sufficient binding region:701-928|maltose binding protein tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q8VSP9	uniprotkb:P06400	intact:EBI-6506625|uniprotkb:Q2ET10|uniprotkb:Q2ET14|uniprotkb:Q6XW10|uniprotkb:Q7BEG0|uniprotkb:Q99Q87	intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163.4	psi-mi:ospf_shifl(display_long)|uniprotkb:ospF(gene name)|psi-mi:ospF(display_short)|uniprotkb:mkaD(gene name synonym)|uniprotkb:Effector protein OspF(gene name synonym)|uniprotkb:pWR501_0013(orf name)|uniprotkb:SFLP011(orf name)|uniprotkb:CP0010(locus name)	psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Zurawski et al. (2009)	pubmed:19017275|imex:IM-18243	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6506654|mpidb:MPIDB-INT-227|imex:IM-18243-3	intact-miscore:0.54	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003519(Salmonella virulence-associated 28 kDa protein)|refseq:NP_858143.1|refseq:YP_006960239.1|refseq:WP_001121867.1|interpro:IPR038498|go:""GO:0005576""(extracellular region)|go:""GO:0016829""(lyase activity)|rcsb pdb:3I0U|refseq:WP_010921598.1|mint:Q8VSP9"	"ensembl:ENSG00000139687.17(gene)|ensembl:ENST00000267163.6(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001894""(tissue homeostasis)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016605""(PML body)|go:""GO:0019900""(kinase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031134""(sister chromatid biorientation)|go:""GO:0031175""(neuron projection development)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034088""(maintenance of mitotic sister chromatid cohesion)|go:""GO:0034349""(glial cell apoptotic process)|go:""GO:0035189""(Rb-E2F complex)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0042551""(neuron maturation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043353""(enucleate erythrocyte differentiation)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043550""(regulation of lipid kinase activity)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0045842""(positive regulation of mitotic metaphase/anaphase transition)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048565""(digestive tract development)|go:""GO:0048667""(cell morphogenesis involved in neuron differentiation)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051276""(chromosome organization)|go:""GO:0051301""(cell division)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061676""(importin-alpha family protein binding)|go:""GO:0061793""(chromatin lock complex)|go:""GO:0071459""(protein localization to chromosome, centromeric region)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071901""(negative regulation of protein serine/threonine kinase activity)|go:""GO:0090230""(regulation of centromere complex assembly)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902948""(negative regulation of tau-protein kinase activity)|go:""GO:1903055""(positive regulation of extracellular matrix organization)|go:""GO:1903944""(negative regulation of hepatocyte apoptotic process)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904761""(negative regulation of myofibroblast differentiation)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000679""(positive regulation of transcription regulatory region DNA binding)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|reactome:R-HSA-9725371|reactome:R-HSA-9841922|refseq:NP_000312.2|efo:""Orphanet:1587""|efo:""Orphanet:357027""|efo:""Orphanet:357034""|efo:""Orphanet:668""|efo:""Orphanet:70573""|dip:DIP-582N|panther:PTHR13742(orthology-group)|ensembl:ENSP00000267163.4"	-	-	-	figure legend:Fig. 8A|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2025/03/31	rogid:mSCbX2cDlV97OQC/v4kEJtqiOIU623	rogid:xidCNX96KlQzu160polvT61k4Zw9606	intact-crc:F6EE43792F77562B|rigid:4NKN/OKB6d0tHnBxkuuZT3QQd2s	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q5ZWZ3	uniprotkb:P62820	intact:EBI-6417967	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:q5zwz3_legph(display_long)|uniprotkb:lpg0940(locus name)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Neunuebel et al. (2012)	pubmed:22228731|imex:IM-18443	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6417972|mpidb:MPIDB-INT-1816|imex:IM-18443-1	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR041463|rcsb pdb:3TNF|refseq:WP_010946675.1|dip:DIP-59799N|mint:Q5ZWZ3|refseq:YP_094974.1	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	figure legend:Figure 3|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2024/11/14	rogid:AyBH7iPqbJYlEKGIubXHtBV/M+U272624	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:F06297C620EA5F6D|rigid:bJUBlq8PJT4Wyb2SP/9Et/NCqSE	false	sufficient binding region:190-600	mutation:70-70|mutation:25-25	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:P62820	uniprotkb:Q7BU69	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	intact:EBI-971514|uniprotkb:Q52295|uniprotkb:Q6XVV7|uniprotkb:Q7BEL1|uniprotkb:Q8VSF1	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	psi-mi:vira_shifl(display_long)|uniprotkb:virA(gene name)|psi-mi:virA(display_short)|uniprotkb:Effector protein VirA(gene name synonym)|uniprotkb:pWR501_0191(orf name)|uniprotkb:CP0181(locus name)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Dong et al. (2012)	pubmed:22939626|imex:IM-17932	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-6379627|imex:IM-17932-6	intact-miscore:0.40	-	"psi-mi:""MI:0500""(biological role)"	"psi-mi:""MI:0500""(biological role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	"go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|refseq:WP_001195004.1|interpro:IPR009669(EspG)|refseq:NP_858314.2|rcsb pdb:3EB8|rcsb pdb:3EE1|rcsb pdb:4FMB|refseq:NP_085345.1|interpro:IPR043098|refseq:YP_009062518.1"	-	-	-	figure legend:Fig. 2D|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-293t)|taxid:9606(Homo sapiens HEK293T embryonic kidney cell)	-	2012/11/02	2025/03/31	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	rogid:nYxyBJIHLvAcA8aSzi0wsVP2Mgo623	intact-crc:5933C7A95C3FECB5|rigid:nVXSTJhycsfeA6zS14hHY+oHZSA	false	flag tag:?-?|mutation decreasing interaction strength:25-25|mutation increasing interaction strength:70-70	myc tag:?-?	-	-	"psi-mi:""MI:0113""(western blot)"	"psi-mi:""MI:0113""(western blot)"
uniprotkb:Q7DB50	uniprotkb:P62820	intact:EBI-6379656|uniprotkb:Q7A9M3|uniprotkb:A0A6M0JN46	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:q7db50_eco57(display_long)|uniprotkb:espG(gene name)|psi-mi:espG(display_short)|uniprotkb:ECs_4590(orf name)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Dong et al. (2012)	pubmed:22939626|imex:IM-17932	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-6379749|imex:IM-17932-9|wwpdb:4fmc	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009669(EspG)|rcsb pdb:3PCR|rcsb pdb:3PCS|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|refseq:WP_001301460.1|interpro:IPR043098|go:""GO:0004197""(cysteine-type endopeptidase activity)|refseq:NP_312617.1"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	3d-resolution:2.8A|3d-r-factors:Rworking = 0.23 Rfree = 0.28|figure legend:Supp. Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/02	2025/03/31	rogid:g7FQ+G0CKEqSrzN+2H+OAnLu7No83334	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:E366399489734D96|rigid:10VBq+4inewuTUWIcyiy8v7PrsE	false	sufficient binding region:30-380	his tag:?-?|sufficient binding region:14-130	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q7DB50	uniprotkb:P62820	intact:EBI-6379656|uniprotkb:Q7A9M3|uniprotkb:A0A6M0JN46	intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286.3|ensembl:ENSP00000497078.1	psi-mi:q7db50_eco57(display_long)|uniprotkb:espG(gene name)|psi-mi:espG(display_short)|uniprotkb:ECs_4590(orf name)	psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym)	"psi-mi:""MI:0114""(x-ray crystallography)"	Dong et al. (2012)	pubmed:22939626|imex:IM-17932	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-6379749|imex:IM-17932-9|wwpdb:4fmc	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009669(EspG)|rcsb pdb:3PCR|rcsb pdb:3PCS|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|refseq:WP_001301460.1|interpro:IPR043098|go:""GO:0004197""(cysteine-type endopeptidase activity)|refseq:NP_312617.1"	"refseq:NP_004152.1|refseq:NP_056358.1|dip:DIP-1063N|ensembl:ENSG00000138069.18(gene)|ensembl:ENST00000409784.8(transcript)|ensembl:ENST00000649427.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006897""(endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016477""(cell migration)|go:""GO:0019068""(virion assembly)|go:""GO:0030252""(growth hormone secretion)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0032402""(melanosome transport)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042470""(melanosome)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045296""(cadherin binding)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090110""(COPII-coated vesicle cargo loading)|go:""GO:1903020""(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR050227|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|rcsb pdb:7EQ2|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|panther:PTHR24073(orthology-group)"	-	-	-	3d-resolution:2.8A|3d-r-factors:Rworking = 0.23 Rfree = 0.28|figure legend:Supp. Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/02	2025/03/31	rogid:g7FQ+G0CKEqSrzN+2H+OAnLu7No83334	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606	intact-crc:E366399489734D96|rigid:10VBq+4inewuTUWIcyiy8v7PrsE	false	sufficient binding region:30-380	his tag:?-?|sufficient binding region:6-176	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P62330	uniprotkb:Q7DB50	intact:EBI-638181|uniprotkb:P26438|intact:EBI-2802827|uniprotkb:Q6FGZ2|ensembl:ENSP00000298316.5|ensembl:ENSP00000510419.1	intact:EBI-6379656|uniprotkb:Q7A9M3|uniprotkb:A0A6M0JN46	psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)	psi-mi:q7db50_eco57(display_long)|uniprotkb:espG(gene name)|psi-mi:espG(display_short)|uniprotkb:ECs_4590(orf name)	"psi-mi:""MI:0114""(x-ray crystallography)"	Dong et al. (2012)	pubmed:22939626|imex:IM-17932	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:83334(eco57)|taxid:83334(""Escherichia coli O157:H7"")"	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-6379789|imex:IM-17932-11|wwpdb:4fme	intact-miscore:0.40	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001654.1|ensembl:ENSG00000165527.8(gene)|ensembl:ENST00000298316.7(transcript)|ensembl:ENST00000693319.1(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001889""(liver development)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007155""(cell adhesion)|go:""GO:0007399""(nervous system development)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019003""(GDP binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030154""(cell differentiation)|go:""GO:0030496""(midbody)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031527""(filopodium membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032456""(endocytic recycling)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0035020""(regulation of Rac protein signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051301""(cell division)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060998""(regulation of dendritic spine development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090162""(establishment of epithelial cell polarity)|go:""GO:0090543""(Flemming body)|go:""GO:0097178""(ruffle assembly)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099562""(maintenance of postsynaptic density structure)|go:""GO:0120183""(positive regulation of focal adhesion disassembly)|go:""GO:1902217""(erythrocyte apoptotic process)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903438""(positive regulation of mitotic cytokinetic process)|go:""GO:1905345""(protein localization to cleavage furrow)|go:""GO:1905606""(regulation of presynapse assembly)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:2000009""(negative regulation of protein localization to cell surface)|go:""GO:2000171""(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR024156|interpro:IPR027417|interpro:IPR041838|mint:P62330|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|rcsb pdb:7RK3|rcsb pdb:7XRD|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N|panther:PTHR11711(orthology-group)"	"interpro:IPR009669(EspG)|rcsb pdb:3PCR|rcsb pdb:3PCS|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|refseq:WP_001301460.1|interpro:IPR043098|go:""GO:0004197""(cysteine-type endopeptidase activity)|refseq:NP_312617.1"	-	-	-	3d-resolution:4.1A|3d-r-factors:Rworking = 0.21 Rfree = 0.25|figure legend:Supp. Table 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/02	2025/03/31	rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606	rogid:g7FQ+G0CKEqSrzN+2H+OAnLu7No83334	intact-crc:401CDD6CB8A96FB0|rigid:aeQ+e67UAXw3WEcZtRGo9tVkm5o	false	sufficient binding region:14-173	sufficient binding region:30-380	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:P60953	uniprotkb:A0A0H2ZTM2	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	intact:EBI-6405926	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:a0a0h2ztm2_myca1(display_long)|uniprotkb:MAV_4139(locus name)	"psi-mi:""MI:0018""(two hybrid)"	Harriff et al. (2009)	pubmed:19060135|imex:IM-18257	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:243243(strain 104)|taxid:243243(Mycobacterium avium)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6405930|mpidb:MPIDB-INT-696|imex:IM-18257-1	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	interpro:IPR042271|uniprotkb:A0QK49(uniprot-removed-ac)|interpro:IPR018766	-	-	-	curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2012/11/30	2024/11/07	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rogid:sKux8jW0sB1dWGn8JIjB6reDFT8243243	intact-crc:923B3054A7BC13D0|rigid:+/AEVEsnSHV0juwN/9kLM8Zje9E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H3A2T3	uniprotkb:P60953	intact:EBI-6405935	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:a0a0h3a2t3_myca1(display_long)|uniprotkb:MAV_1190(locus name)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Harriff et al. (2009)	pubmed:19060135|imex:IM-18257	taxid:243243(strain 104)|taxid:243243(Mycobacterium avium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6405939|mpidb:MPIDB-INT-695|imex:IM-18257-2	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004622""(lysophospholipase activity)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0046470""(phosphatidylcholine metabolic process)|uniprotkb:A0QBZ8(uniprot-removed-ac)|interpro:IPR001423(Lysophospholipase patatin, conserved site)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR050301"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	-	-	-	figure legend:Table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2012/11/30	2024/11/07	rogid:Cc76zVtwPicg5nHxqDpS0vW9Si4243243	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:F319250DE2AD988C|rigid:Rlg25gQMm3gr2+4GqQ1rktwYiZI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H3A1L5	uniprotkb:P60953	intact:EBI-6405944	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	psi-mi:a0a0h3a1l5_myca1(display_long)|uniprotkb:MAV_4671(locus name)	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	"psi-mi:""MI:0018""(two hybrid)"	Harriff et al. (2009)	pubmed:19060135|imex:IM-18257	taxid:243243(strain 104)|taxid:243243(Mycobacterium avium)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6405948|mpidb:MPIDB-INT-694|imex:IM-18257-3	intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|uniprotkb:A0QLL1(uniprot-removed-ac)|refseq:WP_011726184.1|interpro:IPR021373"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	-	-	-	figure legend:Table 3|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2012/11/30	2024/11/07	rogid:skjZHXrdtWRF0qajFliyJZwKMMg243243	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	intact-crc:20DA0A06ABAE4189|rigid:KihGlDteHm5I1REcde+nyVOYNsY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P07339	uniprotkb:P13128	intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671.2	intact:EBI-6407357|uniprotkb:Q57096|uniprotkb:Q48747|uniprotkb:Q57206	psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym)	psi-mi:tacy_lismo(display_long)|uniprotkb:LLO(gene name synonym)|uniprotkb:Thiol-activated cytolysin(gene name synonym)|uniprotkb:hlyA(gene name synonym)|uniprotkb:lisA(gene name synonym)|uniprotkb:lmo0202(locus name)|uniprotkb:hly(gene name)|psi-mi:hly(display_short)	"psi-mi:""MI:0435""(protease assay)"	Carrasco-Marín et al. (2009)	pubmed:19389128|imex:IM-18278	taxid:9606(human)|taxid:9606(Homo sapiens)	"taxid:169963(lismo)|taxid:169963(""Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)"")"	"psi-mi:""MI:0194""(cleavage reaction)"	"psi-mi:""MI:0903""(mpidb)"	intact:EBI-6407373|mpidb:MPIDB-INT-1060|imex:IM-18278-2	intact-miscore:0.44	-	"psi-mi:""MI:0501""(enzyme)"	"psi-mi:""MI:0502""(enzyme target)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR47966(orthology-group)|dip:DIP-43906N|efo:""Orphanet:228337""|ensembl:ENSG00000117984.15(gene)|ensembl:ENST00000236671.7(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0004190""(aspartic-type endopeptidase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|go:""GO:0010008""(endosome membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0031904""(endosome lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0042159""(lipoprotein catabolic process)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070001""(aspartic-type peptidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070201""(regulation of establishment of protein localization)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-9018519|refseq:NP_001900.1"	"go:""GO:0005576""(extracellular region)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0042802""(identical protein binding)|go:""GO:0090729""(toxin activity)|rcsb pdb:4CDB|mint:P13128|interpro:IPR001869(Thiol-activated cytolysin)|refseq:NP_463733.1|refseq:WP_003722731.1|interpro:IPR038700|interpro:IPR035390|interpro:IPR036359|interpro:IPR036363"	-	-	-	figure legend:Fig. 1|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/30	2025/03/31	rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606	rogid:Bv3sXK/HZ4zkspJHx2Zm1tjCCUg169963	intact-crc:30F4130ECAA068ED|rigid:CwNO9XQTKw91uuem4aRIb4Gam3U	false	-	his tag:?-?	-	-	"psi-mi:""MI:0705""(anti tag western blot)"	"psi-mi:""MI:0705""(anti tag western blot)"
uniprotkb:Q99PZ6	uniprotkb:P61077	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	"psi-mi:""MI:0114""(x-ray crystallography)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9316547|imex:IM-23086-1	intact-miscore:0.67	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	rcsb pdb:4BVU	-	-	"figure legend:f1 t1 sf1|comment:""\""we determined the crystal structure of the OspG/UbcH5c-O~Ub complex to 2.70 A (Fig 1A and Table 1). The covalent oxyester linkage between the UbcH5c active site (mutated from cysteine to serine) and the UbC-terminus is maintained in the complex (Supplementary Fig S1A) and binding to OspG does not significantly alter the conformations of either UbcH5c or Ub.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:AADF2188E2EC6F4E|rigid:2YxKRpvWBAVnUXufXewyzqeYjkM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	uniprotkb:P0CG48	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-3390054|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1|ensembl:ENSP00000344818.5|ensembl:ENSP00000441543.1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	"psi-mi:""MI:0114""(x-ray crystallography)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9316547|imex:IM-23086-1	intact-miscore:0.59	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000150991.16(gene)|ensembl:ENST00000339647.6(transcript)|ensembl:ENST00000536769.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019941""(modification-dependent protein catabolic process)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031386""(protein tag activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR050158|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MI8|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3PTF|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6EQI|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7EAL|rcsb pdb:7EAO|rcsb pdb:7EB9|rcsb pdb:7JXV|rcsb pdb:7K6P|rcsb pdb:7K6Q|rcsb pdb:7KEO|rcsb pdb:7M4M|rcsb pdb:7M4N|rcsb pdb:7M4O|rcsb pdb:7MEX|rcsb pdb:7MIC|rcsb pdb:7MYF|rcsb pdb:7NPI|rcsb pdb:7OWD|rcsb pdb:7R70|rcsb pdb:7TV4|rcsb pdb:7UV5|rcsb pdb:7UYH|rcsb pdb:7YUI|rcsb pdb:7ZJ3|rcsb pdb:8A9J|rcsb pdb:8A9K|rcsb pdb:8ADB|rcsb pdb:8AMS|rcsb pdb:8B3G|rcsb pdb:8B3I|rcsb pdb:8E7O|rcsb pdb:8EAZ|rcsb pdb:8EB0|rcsb pdb:8FTQ|rcsb pdb:8OFF|rcsb pdb:8PJN|rcsb pdb:8PMQ|rcsb pdb:8PQL|rcsb pdb:8Q7R|rcsb pdb:8R5H|rcsb pdb:8RX0|rcsb pdb:8SSI|rcsb pdb:8ST7|rcsb pdb:8ST8|rcsb pdb:8ST9|rcsb pdb:8SVF|rcsb pdb:8T48|rcsb pdb:8U5H|rcsb pdb:9FCI|rcsb pdb:9FCJ|rcsb pdb:9FJ3|rcsb pdb:9FJ4|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866427|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-909733|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9680350|reactome:R-HSA-9683683|reactome:R-HSA-9692916|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-9725370|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-9755511|reactome:R-HSA-9758274|reactome:R-HSA-9762114|reactome:R-HSA-977225|reactome:R-HSA-9824878|reactome:R-HSA-9828211|reactome:R-HSA-983168|reactome:R-HSA-9833109|reactome:R-HSA-9861718|refseq:NP_066289.3|panther:PTHR10666(orthology-group)"	rcsb pdb:4BVU	-	-	"figure legend:f1 t1 sf1|comment:""\""we determined the crystal structure of the OspG/UbcH5c-O~Ub complex to 2.70 A (Fig 1A and Table 1). The covalent oxyester linkage between the UbcH5c active site (mutated from cysteine to serine) and the UbC-terminus is maintained in the complex (Supplementary Fig S1A) and binding to OspG does not significantly alter the conformations of either UbcH5c or Ub.\""""|curation depth:imex curation|full coverage:Only protein-protein interactions"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606	intact-crc:AADF2188E2EC6F4E|rigid:2YxKRpvWBAVnUXufXewyzqeYjkM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	uniprotkb:P62837	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-347677|ensembl:ENSP00000381717.3|ensembl:ENSP00000381718.4|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 2""(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D2""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348127|imex:IM-23086-3	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000131508.17(gene)|ensembl:ENST00000398733.8(transcript)|ensembl:ENST00000398734.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036211""(protein modification process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|rcsb pdb:7R71|rcsb pdb:8B3I|rcsb pdb:8GBQ|rcsb pdb:8GCB|rcsb pdb:8GRM|rcsb pdb:8JWJ|rcsb pdb:8JWU|rcsb pdb:8VK8|rcsb pdb:8VK9|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-caco2)|taxid:9606(Homo sapiens CACO2 Caucasian colon adenocarcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:A63DC488F3674DF0|rigid:vs3FzDXbOH/DU63HDUFM3zha3mM	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:P61077	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348127|imex:IM-23086-3	intact-miscore:0.67	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-caco2)|taxid:9606(Homo sapiens CACO2 Caucasian colon adenocarcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:A63DC488F3674DF0|rigid:vs3FzDXbOH/DU63HDUFM3zha3mM	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:P51965	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709.3|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme E1""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348127|imex:IM-23086-3	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_003332.1|refseq:NP_872607.1|ensembl:ENSG00000170142.12(gene)|ensembl:ENST00000306627.8(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032020""(ISG15-protein conjugation)|go:""GO:0042296""(ISG15 transferase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51965|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|rcsb pdb:8IYA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:NP_001189405.1|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-caco2)|taxid:9606(Homo sapiens CACO2 Caucasian colon adenocarcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:A63DC488F3674DF0|rigid:vs3FzDXbOH/DU63HDUFM3zha3mM	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:Q96LR5	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-2129763|ensembl:ENSP00000379931.1|ensembl:ENSP00000401053.1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348127|imex:IM-23086-3	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_689866.1|refseq:XP_005265489.1|dip:DIP-52704N|ensembl:ENSG00000182247.11(gene)|ensembl:ENST00000396703.6(transcript)|ensembl:ENST00000425792.5(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006974""(DNA damage response)|go:""GO:0032020""(ISG15-protein conjugation)|go:""GO:0042296""(ISG15 transferase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:Q96LR5|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-caco2)|taxid:9606(Homo sapiens CACO2 Caucasian colon adenocarcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:A63DC488F3674DF0|rigid:vs3FzDXbOH/DU63HDUFM3zha3mM	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:P68036	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-711173|ensembl:ENSP00000344259.5|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7|intact:EBI-21353523	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348127|imex:IM-23086-3	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000185651.16(gene)|ensembl:ENST00000342192.9(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019899""(enzyme binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0036211""(protein modification process)|go:""GO:0044770""(cell cycle phase transition)|go:""GO:0051443""(positive regulation of ubiquitin-protein transferase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0097027""(ubiquitin-protein transferase activator activity)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR050113|mint:P68036|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|rcsb pdb:7OIK|rcsb pdb:7V8F|rcsb pdb:8EAZ|rcsb pdb:8EB0|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|refseq:NP_003338.1|efo:""Orphanet:536""|dip:DIP-6124N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-caco2)|taxid:9606(Homo sapiens CACO2 Caucasian colon adenocarcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:A63DC488F3674DF0|rigid:vs3FzDXbOH/DU63HDUFM3zha3mM	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:P61086	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-473850|uniprotkb:A6NJC1|uniprotkb:O54806|uniprotkb:P27924|uniprotkb:Q16721|uniprotkb:Q9CVV9|uniprotkb:Q9Y2D3|uniprotkb:B2RDF8|uniprotkb:A8K5Y9|uniprotkb:C9JGP1|ensembl:ENSP00000261427.5	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ube2k_human(display_long)|uniprotkb:HIP2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-25 kDa(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2(gene name synonym)|uniprotkb:UBE2K(gene name)|psi-mi:UBE2K(display_short)|uniprotkb:LIG(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme K(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348127|imex:IM-23086-3	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_001104582.1|refseq:NP_001104583.1|refseq:NP_005330.1|dip:DIP-32524N|panther:PTHR24068(orthology-group)|ensembl:ENSG00000078140.14(gene)|ensembl:ENST00000261427.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0010994""(free ubiquitin chain polymerization)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032433""(filopodium tip)|go:""GO:0032434""(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0034450""(ubiquitin-ubiquitin ligase activity)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR042599|mint:P61086|rcsb pdb:1YLA|rcsb pdb:2O25|rcsb pdb:3E46|rcsb pdb:3F92|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:5DFL|rcsb pdb:6IF1|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:7MYF|rcsb pdb:7MYH|rcsb pdb:7OJX|reactome:R-HSA-8866652|reactome:R-HSA-936440|reactome:R-HSA-983168"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-caco2)|taxid:9606(Homo sapiens CACO2 Caucasian colon adenocarcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:TTxSiXJ5fNdGUeuzYlPvDl8W7eg9606	intact-crc:A63DC488F3674DF0|rigid:vs3FzDXbOH/DU63HDUFM3zha3mM	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:P62837	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-347677|ensembl:ENSP00000381717.3|ensembl:ENSP00000381718.4|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 2""(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D2""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348087|imex:IM-23086-2	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000131508.17(gene)|ensembl:ENST00000398733.8(transcript)|ensembl:ENST00000398734.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036211""(protein modification process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|rcsb pdb:7R71|rcsb pdb:8B3I|rcsb pdb:8GBQ|rcsb pdb:8GCB|rcsb pdb:8GRM|rcsb pdb:8JWJ|rcsb pdb:8JWU|rcsb pdb:8VK8|rcsb pdb:8VK9|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:2DD5183A89F49130|rigid:kPG1eiAtn9dxGIKSmqK+DtQd7Eg	false	yellow fluorescent protein tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:P61077	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348087|imex:IM-23086-2	intact-miscore:0.67	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:2DD5183A89F49130|rigid:kPG1eiAtn9dxGIKSmqK+DtQd7Eg	false	yellow fluorescent protein tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:P51965	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709.3|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme E1""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)"	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348087|imex:IM-23086-2	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_003332.1|refseq:NP_872607.1|ensembl:ENSG00000170142.12(gene)|ensembl:ENST00000306627.8(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032020""(ISG15-protein conjugation)|go:""GO:0042296""(ISG15 transferase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51965|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|rcsb pdb:8IYA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:NP_001189405.1|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:2DD5183A89F49130|rigid:kPG1eiAtn9dxGIKSmqK+DtQd7Eg	false	yellow fluorescent protein tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:P68036	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-711173|ensembl:ENSP00000344259.5|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7|intact:EBI-21353523	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348087|imex:IM-23086-2	intact-miscore:0.56	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000185651.16(gene)|ensembl:ENST00000342192.9(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019899""(enzyme binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0036211""(protein modification process)|go:""GO:0044770""(cell cycle phase transition)|go:""GO:0051443""(positive regulation of ubiquitin-protein transferase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0097027""(ubiquitin-protein transferase activator activity)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR050113|mint:P68036|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|rcsb pdb:7OIK|rcsb pdb:7V8F|rcsb pdb:8EAZ|rcsb pdb:8EB0|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|refseq:NP_003338.1|efo:""Orphanet:536""|dip:DIP-6124N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:2DD5183A89F49130|rigid:kPG1eiAtn9dxGIKSmqK+DtQd7Eg	false	yellow fluorescent protein tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:O14933	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156.4	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	"psi-mi:""MI:0007""(anti tag coimmunoprecipitation)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0914""(association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348087|imex:IM-23086-2	intact-miscore:0.50	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSG00000156587.16(gene)|ensembl:ENST00000287156.9(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0032020""(ISG15-protein conjugation)|go:""GO:0036211""(protein modification process)|go:""GO:0042296""(ISG15 transferase activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR050113|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|rcsb pdb:8OIF|rcsb pdb:8SE9|rcsb pdb:8SEA|rcsb pdb:8SEB|rcsb pdb:8SV8|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9833110|reactome:R-HSA-9833482|dip:DIP-41477N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:9606(human-hela)|taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	intact-crc:2DD5183A89F49130|rigid:kPG1eiAtn9dxGIKSmqK+DtQd7Eg	false	yellow fluorescent protein tag:?-?	-	-	-	"psi-mi:""MI:0427""(Identification by mass spectrometry)"	"psi-mi:""MI:0427""(Identification by mass spectrometry)"
uniprotkb:Q99PZ6	uniprotkb:P51668	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-743540|uniprotkb:A6NLF6|uniprotkb:A8K786|ensembl:ENSP00000363019.3	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 1""(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D1""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348273|imex:IM-23086-4	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_003329.1|dip:DIP-44088N|ensembl:ENSG00000072401.15(gene)|ensembl:ENST00000373910.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902916""(positive regulation of protein polyubiquitination)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|rcsb pdb:7ZJ3|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-5357905|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2 sf2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	intact-crc:361B944C44F8522C|rigid:j5bHK8obvi/HRYXXwlwZRL2ZCEg	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q99PZ6	uniprotkb:P62837	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-347677|ensembl:ENSP00000381717.3|ensembl:ENSP00000381718.4|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 2""(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D2""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348285|imex:IM-23086-5	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000131508.17(gene)|ensembl:ENST00000398733.8(transcript)|ensembl:ENST00000398734.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036211""(protein modification process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|rcsb pdb:7R71|rcsb pdb:8B3I|rcsb pdb:8GBQ|rcsb pdb:8GCB|rcsb pdb:8GRM|rcsb pdb:8JWJ|rcsb pdb:8JWU|rcsb pdb:8VK8|rcsb pdb:8VK9|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2 sf2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	intact-crc:BB65959ACC285346|rigid:Rd5YtShXjSpAuyl+NEBcUW3w5oA	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q99PZ6	uniprotkb:P51965	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709.3|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme E1""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348317|imex:IM-23086-7	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_003332.1|refseq:NP_872607.1|ensembl:ENSG00000170142.12(gene)|ensembl:ENST00000306627.8(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0032020""(ISG15-protein conjugation)|go:""GO:0042296""(ISG15 transferase activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51965|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|rcsb pdb:8IYA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:NP_001189405.1|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2 sf2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	intact-crc:7CCC401F50DE2923|rigid:jimpQcdlfcMqU8YyvUAB7iFy5Xk	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q99PZ6	uniprotkb:Q96LR5	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-2129763|ensembl:ENSP00000379931.1|ensembl:ENSP00000401053.1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348324|imex:IM-23086-8	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_689866.1|refseq:XP_005265489.1|dip:DIP-52704N|ensembl:ENSG00000182247.11(gene)|ensembl:ENST00000396703.6(transcript)|ensembl:ENST00000425792.5(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006974""(DNA damage response)|go:""GO:0032020""(ISG15-protein conjugation)|go:""GO:0042296""(ISG15 transferase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:Q96LR5|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2 sf2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	intact-crc:7CDF177A45437AB0|rigid:UF5LdL8SfCqScT+YIkwLfaitqH8	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q99PZ6	uniprotkb:Q969T4	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-348496|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|ensembl:ENSP00000376215.2|ensembl:ENSP00000386788.3|ensembl:ENSP00000473623.1|ensembl:ENSP00000473639.1|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348330|imex:IM-23086-9	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035.16(gene)|ensembl:ENST00000392415.6(transcript)|ensembl:ENST00000410062.9(transcript)|ensembl:ENST00000602710.5(transcript)|ensembl:ENST00000602959.5(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:Q969T4|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2 sf2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	intact-crc:E5059F9501205071|rigid:0CSsNGE1wMARtcHSs80Lq+oqI10	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q99PZ6	uniprotkb:P61086	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-473850|uniprotkb:A6NJC1|uniprotkb:O54806|uniprotkb:P27924|uniprotkb:Q16721|uniprotkb:Q9CVV9|uniprotkb:Q9Y2D3|uniprotkb:B2RDF8|uniprotkb:A8K5Y9|uniprotkb:C9JGP1|ensembl:ENSP00000261427.5	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ube2k_human(display_long)|uniprotkb:HIP2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-25 kDa(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2(gene name synonym)|uniprotkb:UBE2K(gene name)|psi-mi:UBE2K(display_short)|uniprotkb:LIG(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme K(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348337|imex:IM-23086-10	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_001104582.1|refseq:NP_001104583.1|refseq:NP_005330.1|dip:DIP-32524N|panther:PTHR24068(orthology-group)|ensembl:ENSG00000078140.14(gene)|ensembl:ENST00000261427.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|go:""GO:0010994""(free ubiquitin chain polymerization)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032433""(filopodium tip)|go:""GO:0032434""(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0034450""(ubiquitin-ubiquitin ligase activity)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR042599|mint:P61086|rcsb pdb:1YLA|rcsb pdb:2O25|rcsb pdb:3E46|rcsb pdb:3F92|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:5DFL|rcsb pdb:6IF1|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:7MYF|rcsb pdb:7MYH|rcsb pdb:7OJX|reactome:R-HSA-8866652|reactome:R-HSA-936440|reactome:R-HSA-983168"	-	-	-	figure legend:t2 sf2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:TTxSiXJ5fNdGUeuzYlPvDl8W7eg9606	intact-crc:3F066FCC00B534FD|rigid:nUJqkIhguMAfhFg9q8A+KfSQezQ	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q99PZ6	uniprotkb:O14933	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156.4	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348386|imex:IM-23086-13	intact-miscore:0.50	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSG00000156587.16(gene)|ensembl:ENST00000287156.9(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0032020""(ISG15-protein conjugation)|go:""GO:0036211""(protein modification process)|go:""GO:0042296""(ISG15 transferase activity)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR050113|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|rcsb pdb:8OIF|rcsb pdb:8SE9|rcsb pdb:8SEA|rcsb pdb:8SEB|rcsb pdb:8SV8|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-9833110|reactome:R-HSA-9833482|dip:DIP-41477N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2 sf2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606	intact-crc:B4F72DA19A4E71E1|rigid:pwF6QrpQ8rtv/Y8zubZQaUxwoVE	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q99PZ6	uniprotkb:P61077	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348291|imex:IM-23086-6	intact-miscore:0.67	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2 sf2b f3b sf5b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:A3D378717297EA3B|rigid:gV6DFL8Kb0t+QsXQaJXt2q85yJk	false	glutathione s tranferase tag:?-?	mutation disrupting interaction:62-62	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q99PZ6	uniprotkb:P68036	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-711173|ensembl:ENSP00000344259.5|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7|intact:EBI-21353523	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348371|imex:IM-23086-12	intact-miscore:0.56	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000185651.16(gene)|ensembl:ENST00000342192.9(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019899""(enzyme binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0036211""(protein modification process)|go:""GO:0044770""(cell cycle phase transition)|go:""GO:0051443""(positive regulation of ubiquitin-protein transferase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0071383""(cellular response to steroid hormone stimulus)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0097027""(ubiquitin-protein transferase activator activity)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|interpro:IPR050113|mint:P68036|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|rcsb pdb:7OIK|rcsb pdb:7V8F|rcsb pdb:8EAZ|rcsb pdb:8EB0|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|refseq:NP_003338.1|efo:""Orphanet:536""|dip:DIP-6124N|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2 sf2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	intact-crc:36B61ED2BD2C9E1F|rigid:D3ifyt2VNfFOazL+qfypeuhGmkc	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q99PZ6	uniprotkb:P61088	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176.2	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	"psi-mi:""MI:0096""(pull down)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348355|imex:IM-23086-11	intact-miscore:0.40	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889.10(gene)|ensembl:ENST00000318066.7(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000729""(DNA double-strand break processing)|go:""GO:0003723""(RNA binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006282""(regulation of DNA repair)|go:""GO:0006301""(postreplication repair)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031371""(ubiquitin conjugating enzyme complex)|go:""GO:0031372""(UBC13-MMS2 complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0097027""(ubiquitin-protein transferase activator activity)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140252""(regulation protein catabolic process at postsynapse)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1902523""(positive regulation of protein K63-linked ubiquitination)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:2000781""(positive regulation of double-strand break repair)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61088|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:9BIV|reactome:R-HSA-1169408|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5205685|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-9705671|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:t2 sf2b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2025/03/31	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	intact-crc:B7E3653463AAB99A|rigid:d0D0A6sQSMw3nHRcLfA18B97FYo	false	glutathione s tranferase tag:?-?	-	-	-	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"	"psi-mi:""MI:0818""(molecular weight estimation by coomasie staining)"
uniprotkb:Q99PZ6	uniprotkb:P61077	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	"psi-mi:""MI:0077""(nuclear magnetic resonance)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348594|imex:IM-23086-14	intact-miscore:0.67	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:f4b sf4b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:597C5D348A67C4E6|rigid:2YxKRpvWBAVnUXufXewyzqeYjkM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	uniprotkb:P0CG48	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-3390054|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1|ensembl:ENSP00000344818.5|ensembl:ENSP00000441543.1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	"psi-mi:""MI:0077""(nuclear magnetic resonance)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348594|imex:IM-23086-14	intact-miscore:0.59	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000150991.16(gene)|ensembl:ENST00000339647.6(transcript)|ensembl:ENST00000536769.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019941""(modification-dependent protein catabolic process)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031386""(protein tag activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR050158|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MI8|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3PTF|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6EQI|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7EAL|rcsb pdb:7EAO|rcsb pdb:7EB9|rcsb pdb:7JXV|rcsb pdb:7K6P|rcsb pdb:7K6Q|rcsb pdb:7KEO|rcsb pdb:7M4M|rcsb pdb:7M4N|rcsb pdb:7M4O|rcsb pdb:7MEX|rcsb pdb:7MIC|rcsb pdb:7MYF|rcsb pdb:7NPI|rcsb pdb:7OWD|rcsb pdb:7R70|rcsb pdb:7TV4|rcsb pdb:7UV5|rcsb pdb:7UYH|rcsb pdb:7YUI|rcsb pdb:7ZJ3|rcsb pdb:8A9J|rcsb pdb:8A9K|rcsb pdb:8ADB|rcsb pdb:8AMS|rcsb pdb:8B3G|rcsb pdb:8B3I|rcsb pdb:8E7O|rcsb pdb:8EAZ|rcsb pdb:8EB0|rcsb pdb:8FTQ|rcsb pdb:8OFF|rcsb pdb:8PJN|rcsb pdb:8PMQ|rcsb pdb:8PQL|rcsb pdb:8Q7R|rcsb pdb:8R5H|rcsb pdb:8RX0|rcsb pdb:8SSI|rcsb pdb:8ST7|rcsb pdb:8ST8|rcsb pdb:8ST9|rcsb pdb:8SVF|rcsb pdb:8T48|rcsb pdb:8U5H|rcsb pdb:9FCI|rcsb pdb:9FCJ|rcsb pdb:9FJ3|rcsb pdb:9FJ4|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866427|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-909733|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9680350|reactome:R-HSA-9683683|reactome:R-HSA-9692916|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-9725370|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-9755511|reactome:R-HSA-9758274|reactome:R-HSA-9762114|reactome:R-HSA-977225|reactome:R-HSA-9824878|reactome:R-HSA-9828211|reactome:R-HSA-983168|reactome:R-HSA-9833109|reactome:R-HSA-9861718|refseq:NP_066289.3|panther:PTHR10666(orthology-group)"	-	-	-	figure legend:f4b sf4b|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606	intact-crc:597C5D348A67C4E6|rigid:2YxKRpvWBAVnUXufXewyzqeYjkM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	uniprotkb:P61077	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-348268|ensembl:ENSP00000318494.7|ensembl:ENSP00000337208.3|ensembl:ENSP00000344069.8|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|ensembl:ENSP00000378280.4|uniprotkb:Q6NXS4|ensembl:ENSP00000378282.5|ensembl:ENSP00000378283.2|ensembl:ENSP00000396901.2|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	"psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:""Ubiquitin-conjugating enzyme E2(17)KB 3""(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:""(E3-independent) E2 ubiquitin-conjugating enzyme D3""(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)"	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348699|imex:IM-23086-16	intact-miscore:0.67	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000109332.20(gene)|ensembl:ENST00000321805.11(transcript)|ensembl:ENST00000338145.7(transcript)|ensembl:ENST00000349311.12(transcript)|ensembl:ENST00000394801.8(transcript)|ensembl:ENST00000394803.9(transcript)|ensembl:ENST00000394804.6(transcript)|ensembl:ENST00000453744.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006915""(apoptotic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0036211""(protein modification process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0085020""(protein K6-linked ubiquitination)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P61077|rcsb pdb:1X23|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|rcsb pdb:7LYB|rcsb pdb:8AMS|rcsb pdb:8GRQ|rcsb pdb:8SMW|rcsb pdb:8SMX|rcsb pdb:8SMY|rcsb pdb:8SMZ|rcsb pdb:8SN0|rcsb pdb:8SN1|rcsb pdb:8SN2|rcsb pdb:8SN3|rcsb pdb:8SN4|rcsb pdb:8SN5|rcsb pdb:8SN6|rcsb pdb:8SN7|rcsb pdb:8SN8|rcsb pdb:8SN9|rcsb pdb:8SNA|rcsb pdb:8U14|rcsb pdb:8UPF|rcsb pdb:8UQ8|rcsb pdb:8UQ9|rcsb pdb:8UQA|rcsb pdb:8UQB|rcsb pdb:8UQC|rcsb pdb:8UQD|rcsb pdb:8UQE|rcsb pdb:8X7I|rcsb pdb:8X7J|rcsb pdb:8X7K|rcsb pdb:9IPU|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-5205685|reactome:R-HSA-5357905|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-29062N|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|panther:PTHR24068(orthology-group)"	-	-	-	figure legend:f5a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	intact-crc:2BD5E893A8C71FFA|rigid:2YxKRpvWBAVnUXufXewyzqeYjkM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:Q99PZ6	uniprotkb:P0CG48	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9	intact:EBI-3390054|uniprotkb:Q9BWD6|uniprotkb:P02249|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q9UPK7|uniprotkb:P62988|uniprotkb:P02250|uniprotkb:Q9UEK8|uniprotkb:Q6LDU5|uniprotkb:Q91888|uniprotkb:Q6LBL4|uniprotkb:Q9UEF2|uniprotkb:Q29120|uniprotkb:P02248|uniprotkb:Q9BX98|uniprotkb:Q9UEG1|ensembl:ENSP00000344818.5|ensembl:ENSP00000441543.1	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubc_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	"psi-mi:""MI:0065""(isothermal titration calorimetry)"	Pruneda et al. (2014)	imex:IM-23086|pubmed:24446487	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0471""(MINT)"	intact:EBI-9348699|imex:IM-23086-16	intact-miscore:0.59	"psi-mi:""MI:1060""(spoke expansion)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0497""(neutral component)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q99PZ6|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|refseq:YP_009062537.1|go:""GO:0005615""(extracellular space)|go:""GO:0016301""(kinase activity)|go:""GO:0043657""(host cell)|go:""GO:0046777""(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR054466|rcsb pdb:4BVU"	"ensembl:ENSG00000150991.16(gene)|ensembl:ENST00000339647.6(transcript)|ensembl:ENST00000536769.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019941""(modification-dependent protein catabolic process)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031386""(protein tag activity)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031982""(vesicle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR050158|mint:P0CG48|rcsb pdb:1C3T|rcsb pdb:1CMX|rcsb pdb:1D3Z|rcsb pdb:1F9J|rcsb pdb:1FXT|rcsb pdb:1G6J|rcsb pdb:1GJZ|rcsb pdb:1NBF|rcsb pdb:1OGW|rcsb pdb:1Q5W|rcsb pdb:1S1Q|rcsb pdb:1SIF|rcsb pdb:1TBE|rcsb pdb:1UBI|rcsb pdb:1UBQ|rcsb pdb:1UD7|rcsb pdb:1XD3|rcsb pdb:1XQQ|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:1ZGU|rcsb pdb:2AYO|rcsb pdb:2BGF|rcsb pdb:2DEN|rcsb pdb:2FUH|rcsb pdb:2G45|rcsb pdb:2GBJ|rcsb pdb:2GBK|rcsb pdb:2GBM|rcsb pdb:2GBN|rcsb pdb:2GBR|rcsb pdb:2GMI|rcsb pdb:2HTH|rcsb pdb:2IBI|rcsb pdb:2J7Q|rcsb pdb:2JF5|rcsb pdb:2JRI|rcsb pdb:2JY6|rcsb pdb:2JZZ|rcsb pdb:2K25|rcsb pdb:2K6D|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:2KDF|rcsb pdb:2KHW|rcsb pdb:2KJH|rcsb pdb:2KLG|rcsb pdb:2KN5|rcsb pdb:2KX0|rcsb pdb:2L3Z|rcsb pdb:2LD9|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LZ6|rcsb pdb:2MBO|rcsb pdb:2MBQ|rcsb pdb:2MCN|rcsb pdb:2MI8|rcsb pdb:2MJ5|rcsb pdb:2MOR|rcsb pdb:2MRE|rcsb pdb:2MWS|rcsb pdb:2N2K|rcsb pdb:2NR2|rcsb pdb:2O6V|rcsb pdb:2OJR|rcsb pdb:2PE9|rcsb pdb:2PEA|rcsb pdb:2RR9|rcsb pdb:2RU6|rcsb pdb:2W9N|rcsb pdb:2WDT|rcsb pdb:2XEW|rcsb pdb:2Y5B|rcsb pdb:2Z59|rcsb pdb:2ZCB|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3A33|rcsb pdb:3ALB|rcsb pdb:3AUL|rcsb pdb:3B08|rcsb pdb:3B0A|rcsb pdb:3BY4|rcsb pdb:3C0R|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EEC|rcsb pdb:3EFU|rcsb pdb:3EHV|rcsb pdb:3H7P|rcsb pdb:3H7S|rcsb pdb:3HM3|rcsb pdb:3I3T|rcsb pdb:3IFW|rcsb pdb:3IHP|rcsb pdb:3JSV|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3K9O|rcsb pdb:3K9P|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:3LDZ|rcsb pdb:3MHS|rcsb pdb:3MTN|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3N3K|rcsb pdb:3NS8|rcsb pdb:3O65|rcsb pdb:3OFI|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3ONS|rcsb pdb:3PRM|rcsb pdb:3PT2|rcsb pdb:3PTF|rcsb pdb:3Q3F|rcsb pdb:3RUL|rcsb pdb:3TMP|rcsb pdb:3U30|rcsb pdb:3UGB|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:3VFK|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3WXE|rcsb pdb:3WXF|rcsb pdb:3ZLZ|rcsb pdb:3ZNH|rcsb pdb:3ZNI|rcsb pdb:3ZNZ|rcsb pdb:4AP4|rcsb pdb:4AUQ|rcsb pdb:4BOS|rcsb pdb:4BOZ|rcsb pdb:4BVU|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4FJV|rcsb pdb:4HK2|rcsb pdb:4HXD|rcsb pdb:4I6L|rcsb pdb:4I6N|rcsb pdb:4IG7|rcsb pdb:4IUM|rcsb pdb:4JQW|rcsb pdb:4K1R|rcsb pdb:4K7S|rcsb pdb:4K7U|rcsb pdb:4K7W|rcsb pdb:4KSK|rcsb pdb:4KSL|rcsb pdb:4LCD|rcsb pdb:4LDT|rcsb pdb:4MDK|rcsb pdb:4MM3|rcsb pdb:4MSM|rcsb pdb:4MSQ|rcsb pdb:4NQK|rcsb pdb:4UN2|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZP|rcsb pdb:4XOK|rcsb pdb:4XOL|rcsb pdb:4ZQS|rcsb pdb:5A5B|rcsb pdb:5AF4|rcsb pdb:5AF5|rcsb pdb:5AF6|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5B83|rcsb pdb:5C7J|rcsb pdb:5C7M|rcsb pdb:5E6J|rcsb pdb:5H07|rcsb pdb:5NL4|rcsb pdb:5NLF|rcsb pdb:5NLI|rcsb pdb:5NMC|rcsb pdb:5OE7|rcsb pdb:5OHV|rcsb pdb:5OXH|rcsb pdb:5OXI|rcsb pdb:5UDH|rcsb pdb:5WQ4|rcsb pdb:5ZQ3|rcsb pdb:5ZQ4|rcsb pdb:5ZQ5|rcsb pdb:5ZQ6|rcsb pdb:5ZQ7|rcsb pdb:6A43|rcsb pdb:6A44|rcsb pdb:6AQR|rcsb pdb:6B7M|rcsb pdb:6B7O|rcsb pdb:6EQI|rcsb pdb:6K2U|rcsb pdb:6KBE|rcsb pdb:6N13|rcsb pdb:6N6R|rcsb pdb:6NQA|rcsb pdb:6NXK|rcsb pdb:6OI4|rcsb pdb:6P5B|rcsb pdb:6Q00|rcsb pdb:6QML|rcsb pdb:6RYA|rcsb pdb:6S53|rcsb pdb:6SQR|rcsb pdb:6T7F|rcsb pdb:6T9L|rcsb pdb:6TNF|rcsb pdb:6TTU|rcsb pdb:6TUV|rcsb pdb:6TXB|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:6UPU|rcsb pdb:6V5D|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:6VEN|rcsb pdb:6W9D|rcsb pdb:6W9R|rcsb pdb:6W9S|rcsb pdb:6WJD|rcsb pdb:6WKR|rcsb pdb:6WTG|rcsb pdb:6Z7V|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|rcsb pdb:7EAL|rcsb pdb:7EAO|rcsb pdb:7EB9|rcsb pdb:7JXV|rcsb pdb:7K6P|rcsb pdb:7K6Q|rcsb pdb:7KEO|rcsb pdb:7M4M|rcsb pdb:7M4N|rcsb pdb:7M4O|rcsb pdb:7MEX|rcsb pdb:7MIC|rcsb pdb:7MYF|rcsb pdb:7NPI|rcsb pdb:7OWD|rcsb pdb:7R70|rcsb pdb:7TV4|rcsb pdb:7UV5|rcsb pdb:7UYH|rcsb pdb:7YUI|rcsb pdb:7ZJ3|rcsb pdb:8A9J|rcsb pdb:8A9K|rcsb pdb:8ADB|rcsb pdb:8AMS|rcsb pdb:8B3G|rcsb pdb:8B3I|rcsb pdb:8E7O|rcsb pdb:8EAZ|rcsb pdb:8EB0|rcsb pdb:8FTQ|rcsb pdb:8OFF|rcsb pdb:8PJN|rcsb pdb:8PMQ|rcsb pdb:8PQL|rcsb pdb:8Q7R|rcsb pdb:8R5H|rcsb pdb:8RX0|rcsb pdb:8SSI|rcsb pdb:8ST7|rcsb pdb:8ST8|rcsb pdb:8ST9|rcsb pdb:8SVF|rcsb pdb:8T48|rcsb pdb:8U5H|rcsb pdb:9FCI|rcsb pdb:9FCJ|rcsb pdb:9FJ3|rcsb pdb:9FJ4|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866427|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-909733|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9680350|reactome:R-HSA-9683683|reactome:R-HSA-9692916|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-9725370|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-9755511|reactome:R-HSA-9758274|reactome:R-HSA-9762114|reactome:R-HSA-977225|reactome:R-HSA-9824878|reactome:R-HSA-9828211|reactome:R-HSA-983168|reactome:R-HSA-9833109|reactome:R-HSA-9861718|refseq:NP_066289.3|panther:PTHR10666(orthology-group)"	-	-	-	figure legend:f5a|curation depth:imex curation|full coverage:Only protein-protein interactions	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/27	2024/11/14	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:BM+LHQXjMaUn8RZfq1h9jsAAqcs9606	intact-crc:2BD5E893A8C71FFA|rigid:2YxKRpvWBAVnUXufXewyzqeYjkM	false	-	-	-	-	"psi-mi:""MI:0396""(predetermined participant)"	"psi-mi:""MI:0396""(predetermined participant)"
uniprotkb:O96005	uniprotkb:A0A380SAV6	intact:EBI-2873194|uniprotkb:Q53ET6|uniprotkb:Q9BSS5|uniprotkb:B3KQH2|uniprotkb:B4DDS3|uniprotkb:B4E2X9|uniprotkb:B7Z9X9|uniprotkb:F5H8J3|ensembl:ENSP00000336994.4	intact:EBI-2844158|uniprotkb:Q0WEB4|uniprotkb:Q7CIT4|uniprotkb:A0A384LPZ8	psi-mi:clpt1_human(display_long)|uniprotkb:CLPTM1(gene name)|psi-mi:CLPTM1(display_short)|uniprotkb:Cleft lip and palate transmembrane protein 1(gene name synonym)	psi-mi:a0a380sav6_yerpe(display_long)|uniprotkb:ppsA(gene name synonym)|uniprotkb:pps(gene name)|psi-mi:pps(display_short)|uniprotkb:Pyruvate, water dikinase(gene name synonym)|uniprotkb:YPO2409(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873191|imex:IM-13779-8015	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001285.1|refseq:NP_001269104.1|refseq:NP_001269105.1|ensembl:ENSG00000104853.16(gene)|ensembl:ENST00000337392.10(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0033081""(regulation of T cell differentiation in thymus)|go:""GO:0050811""(GABA receptor binding)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|mint:O96005|panther:PTHR21347(orthology-group)"	"interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR006319(Phosphoenolpyruvate synthase)|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR002192(Pyruvate phosphate dikinase, PEP/pyruvate-binding)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018274|interpro:IPR023151|go:""GO:0005524""(ATP binding)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0008986""(pyruvate, water dikinase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002211813.1|interpro:IPR040442|interpro:IPR036637|refseq:YP_002347374.1|panther:PTHR43030(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CFQ2o5QzCYtIDaxlVtJlA6FEMgU9606	rogid:nQ2ifmi7FAK38H5Y8B/dF0x0e1s632	intact-crc:B86B5565F5A8D835|rigid:dfrxgilZZyef/yYt/xRfe5meBn4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YJT1	uniprotkb:Q00610	intact:EBI-2868360	intact:EBI-354967|intact:EBI-28974011|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00|ensembl:ENSP00000269122.3|ensembl:ENSP00000515147.1	psi-mi:a0a5p8yjt1_yerpe(display_long)|uniprotkb:fliG2(gene name)|psi-mi:fliG2(display_short)|uniprotkb:fliG_2(gene name synonym)|uniprotkb:NCTC5923_04512(orf name)|uniprotkb:YP_3027(locus name)|uniprotkb:y3463(locus name)	psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873211|imex:IM-13779-8014	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T555(uniprot-removed-ac)|interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR023087|interpro:IPR028263|interpro:IPR032779|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:WP_002211442.1"	"ensembl:ENSG00000141367.14(gene)|ensembl:ENST00000269122.8(transcript)|ensembl:ENST00000700707.1(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030118""(clathrin coat)|go:""GO:0030130""(clathrin coat of trans-Golgi network vesicle)|go:""GO:0030132""(clathrin coat of coated pit)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0032051""(clathrin light chain binding)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033572""(transferrin transport)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042470""(melanosome)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051301""(cell division)|go:""GO:0060236""(regulation of mitotic spindle organization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071439""(clathrin complex)|go:""GO:0072318""(clathrin coat disassembly)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:1900126""(negative regulation of hyaluronan biosynthetic process)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990381""(ubiquitin-specific protease binding)|go:""GO:1990498""(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|rcsb pdb:7BN1|rcsb pdb:7BN2|rcsb pdb:7ZX4|rcsb pdb:9C0Y|rcsb pdb:9C0Z|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9700645|reactome:R-HSA-9725370|refseq:NP_004850.1|efo:""Orphanet:178342""|efo:""Orphanet:178469""|efo:""Orphanet:319308""|efo:""Orphanet:442835""|panther:PTHR10292(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7WzgpJGBWCUem6JWSNRZVNV694Y632	rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606	intact-crc:ABBBA98D65966BA5|rigid:UkzyjRvE9B4+521M7T0RiBJpBcY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H2S0	uniprotkb:Q2KHT3	intact:EBI-2845117|uniprotkb:Q74SK9|uniprotkb:Q0WCU8|uniprotkb:Q7CJE4|uniprotkb:A0A384LH60	intact:EBI-2873257|uniprotkb:Q6ZTB2|uniprotkb:O15058|ensembl:ENSP00000387122.1	psi-mi:a0a2u2h2s0_yerpe(display_long)|uniprotkb:dmsB(gene name)|psi-mi:dmsB(display_short)|uniprotkb:YPO2966(locus name)	psi-mi:cl16a_human(display_long)|uniprotkb:CLEC16A(gene name)|psi-mi:CLEC16A(display_short)|uniprotkb:KIAA0350(gene name synonym)|uniprotkb:C-type lectin domain family 16 member A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873264|imex:IM-13779-8021	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR014297(Dimethylsulphoxide reductase, chain B)|interpro:IPR017900|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002211603.1|refseq:YP_002347890.1|interpro:IPR050954|panther:PTHR43177(orthology-group)"	"refseq:NP_001230332.1|refseq:NP_056041.1|ensembl:ENSG00000038532.17(gene)|ensembl:ENST00000409790.6(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007034""(vacuolar transport)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010008""(endosome membrane)|go:""GO:0016197""(endosomal transport)|go:""GO:0031982""(vesicle)|go:""GO:1901096""(regulation of autophagosome maturation)|go:""GO:1901097""(negative regulation of autophagosome maturation)|go:""GO:1904263""(positive regulation of TORC1 signaling)|interpro:IPR019155|interpro:IPR039272|interpro:IPR045820|mint:Q2KHT3|panther:PTHR21481(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9jyIOCO41ainU3jSCjdpHqWlt50632	rogid:dR07OPCgk8rvhcNRGgUM09OjvzY9606	intact-crc:952948E65D3B7803|rigid:1cnf4809P1c61jSphwxdrDWSUxc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W496	uniprotkb:Q8IUN9	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	intact:EBI-2873246|uniprotkb:A8K8J8|uniprotkb:Q14538|uniprotkb:Q6PIW3|ensembl:ENSP00000254868.4	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	psi-mi:clc10_human(display_long)|uniprotkb:CLEC10A(gene name)|psi-mi:CLEC10A(display_short)|uniprotkb:CLECSF13(gene name synonym)|uniprotkb:CLECSF14(gene name synonym)|uniprotkb:HML(gene name synonym)|uniprotkb:C-type lectin superfamily member 14(gene name synonym)|uniprotkb:Macrophage lectin 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873243|imex:IM-13779-8019	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"refseq:NP_006335.2|refseq:NP_878910.1|ensembl:ENSG00000132514.14(gene)|ensembl:ENST00000254868.8(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042806""(fucose binding)|go:""GO:0045087""(innate immune response)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|interpro:IPR050111|mint:Q8IUN9|rcsb pdb:6PUV|rcsb pdb:6PY1|rcsb pdb:6W12|rcsb pdb:6XIY|reactome:R-HSA-5621480|panther:PTHR22802(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	rogid:A2ht6nNtjz7UYJus2hFYohlPhEM9606	intact-crc:58AAB7134409EA32|rigid:s7WrxNJMNWtXggEG3OAjM/2uwsw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UJ71	uniprotkb:Q8Z9R8	intact:EBI-2873235|ensembl:ENSP00000386378.3	intact:EBI-2839934|uniprotkb:Q0W9Q7|intact:EBI-2857683|intact:EBI-2870000	psi-mi:clc4k_human(display_long)|uniprotkb:CD207(gene name)|psi-mi:CD207(display_short)|uniprotkb:CLEC4K(gene name synonym)|uniprotkb:Langerin(gene name synonym)	psi-mi:mnmg_yerpe(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:YPO4130(locus name)|uniprotkb:y4144(locus name)|uniprotkb:YP_4037(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873232|imex:IM-13779-8018	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056532.4|refseq:XP_011531176.1|ensembl:ENSG00000116031.9(gene)|ensembl:ENST00000410009.5(transcript)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0051607""(defense response to virus)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|interpro:IPR050111|rcsb pdb:3C22|rcsb pdb:3KQG|rcsb pdb:3P5D|rcsb pdb:3P5E|rcsb pdb:3P5F|rcsb pdb:3P5G|rcsb pdb:3P5H|rcsb pdb:3P5I|rcsb pdb:3P7F|rcsb pdb:3P7G|rcsb pdb:3P7H|rcsb pdb:4AK8|rcsb pdb:4N32|rcsb pdb:4N33|rcsb pdb:4N34|rcsb pdb:4N35|rcsb pdb:4N36|rcsb pdb:4N37|rcsb pdb:4N38|rcsb pdb:5G6U|rcsb pdb:7WZ8|rcsb pdb:7YTQ|reactome:R-HSA-1236978|panther:PTHR22802(orthology-group)"	"interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|interpro:IPR044920|interpro:IPR026904|refseq:WP_002212259.1|interpro:IPR049312|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|interpro:IPR047001|refseq:YP_002348981.1|interpro:IPR040131|panther:PTHR11806(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8K07ivKTEINXWgtJegC/DeWzU+w9606	rogid:v90IkqKm+dlosxfAPKVYWCflBG4632	intact-crc:37DA2065AA807926|rigid:dtajeD3z7d8KbXNGixXngUwfPQE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09496	uniprotkb:A0A5P8YB62	intact:EBI-1171169|uniprotkb:Q53XZ1|uniprotkb:Q2XPN5|uniprotkb:A8K4W3|uniprotkb:B4DIN1|uniprotkb:F5H6N3|ensembl:ENSP00000242285.6	intact:EBI-2844412|uniprotkb:Q74RA2|uniprotkb:Q0WAD3|uniprotkb:Q7CKZ7|uniprotkb:A0A0H2W7C0|uniprotkb:A0A384KQ85	psi-mi:clca_human(display_long)|uniprotkb:CLTA(gene name)|psi-mi:CLTA(display_short)	psi-mi:a0a5p8yb62_yerpe(display_long)|uniprotkb:YPO3879(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873225|imex:IM-13779-8020	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001070145.1|refseq:NP_001824.1|refseq:NP_009027.1|refseq:NP_001171689.1|refseq:NP_001171691.1|panther:PTHR10639(orthology-group)|ensembl:ENSG00000122705.18(gene)|ensembl:ENST00000242285.11(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0016020""(membrane)|go:""GO:0030118""(clathrin coat)|go:""GO:0030125""(clathrin vesicle coat)|go:""GO:0030130""(clathrin coat of trans-Golgi network vesicle)|go:""GO:0030132""(clathrin coat of coated pit)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032050""(clathrin heavy chain binding)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0042277""(peptide binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0051020""(GTPase binding)|go:""GO:0051301""(cell division)|go:""GO:0071439""(clathrin complex)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098835""(presynaptic endocytic zone membrane)|go:""GO:0099631""(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P09496|rcsb pdb:6E5N|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038"	"interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR018030|interpro:IPR025885|interpro:IPR025949|interpro:IPR043142|refseq:WP_002211999.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR042186|interpro:IPR037224|refseq:YP_002348755.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RCF3QpQKI1yZFOTAyzhvRkR9ek49606	rogid:LoLtCTl+KcIEJlQnZYPeOB8LOg4632	intact-crc:3E0163BFAD07E0E2|rigid:l+wpQiS0ve/MySyzEMl3zCEdOjQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYS8	uniprotkb:Q00610	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	intact:EBI-354967|intact:EBI-28974011|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00|ensembl:ENSP00000269122.3|ensembl:ENSP00000515147.1	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873218|imex:IM-13779-8017	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	"ensembl:ENSG00000141367.14(gene)|ensembl:ENST00000269122.8(transcript)|ensembl:ENST00000700707.1(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030118""(clathrin coat)|go:""GO:0030130""(clathrin coat of trans-Golgi network vesicle)|go:""GO:0030132""(clathrin coat of coated pit)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0032051""(clathrin light chain binding)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033572""(transferrin transport)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042470""(melanosome)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051301""(cell division)|go:""GO:0060236""(regulation of mitotic spindle organization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071439""(clathrin complex)|go:""GO:0072318""(clathrin coat disassembly)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0072686""(mitotic spindle)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:1900126""(negative regulation of hyaluronan biosynthetic process)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1990381""(ubiquitin-specific protease binding)|go:""GO:1990498""(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|rcsb pdb:7BN1|rcsb pdb:7BN2|rcsb pdb:7ZX4|rcsb pdb:9C0Y|rcsb pdb:9C0Z|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9700645|reactome:R-HSA-9725370|refseq:NP_004850.1|efo:""Orphanet:178342""|efo:""Orphanet:178469""|efo:""Orphanet:319308""|efo:""Orphanet:442835""|panther:PTHR10292(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606	intact-crc:CF84742B6BCC6EEC|rigid:4647Ca8sz8IYhWG3bx9QFTv6474	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5L2Q1	uniprotkb:Q96JB5	intact:EBI-2845751	intact:EBI-718818|uniprotkb:Q53FA2|uniprotkb:Q9H3F8|uniprotkb:Q9H8G0|uniprotkb:Q9HBR9|uniprotkb:D3DTU1|uniprotkb:D3DTU2|ensembl:ENSP00000344683.4|uniprotkb:B7Z6N4|uniprotkb:F5H3I5	psi-mi:a0a3g5l2q1_yerpe(display_long)|uniprotkb:rcsD_1(gene name)|psi-mi:rcsD_1(display_short)|uniprotkb:NCTC5923_01909(orf name)|uniprotkb:y2968(locus name)	psi-mi:ck5p3_human(display_long)|uniprotkb:CDK5 activator-binding protein C53(gene name synonym)|uniprotkb:Protein HSF-27(gene name synonym)|uniprotkb:CDK5RAP3(gene name)|psi-mi:CDK5RAP3(display_short)|uniprotkb:IC53(gene name synonym)|uniprotkb:MSTP016(orf name)|uniprotkb:OK/SW-cl.114(orf name)|uniprotkb:PP1553(orf name)|uniprotkb:LXXLL/leucine-zipper-containing ARF-binding protein(gene name synonym)|uniprotkb:LZAP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873299|imex:IM-13779-8024	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T660(uniprot-removed-ac)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036890|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0016020""(membrane)|go:""GO:0016740""(transferase activity)|refseq:WP_002216093.1"	"refseq:NP_788276.1|refseq:NP_001265126.1|ensembl:ENSG00000108465.15(gene)|ensembl:ENST00000338399.9(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0001889""(liver development)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0007420""(brain development)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010921""(regulation of phosphatase activity)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030262""(apoptotic nuclear changes)|go:""GO:0030332""(cyclin binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0044818""(mitotic G2/M transition checkpoint)|go:""GO:0045664""(regulation of neuron differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0060318""(definitive erythrocyte differentiation)|go:""GO:0071569""(protein ufmylation)|go:""GO:0071901""(negative regulation of protein serine/threonine kinase activity)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:0140501""(positive regulation of reticulophagy)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1901798""(positive regulation of signal transduction by p53 class mediator)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR008491(Protein of unknown function DUF773)|mint:Q96JB5|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8QFC|refseq:NP_001265127.1|refseq:NP_001265145.1|refseq:NP_001265146.1|refseq:XP_011523599.1|refseq:XP_016880653.1|refseq:XP_016880654.1|panther:PTHR14894(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:r4uXUojxy6U1CFud51vTXRXZz/k632	rogid:K1S/DQ6fYeOm+MiiGicED0chJAw9606	intact-crc:1AE7E366931496B0|rigid:uKj98nYBIpwUh2MHx5yQeJ8a+Ck	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1D2	uniprotkb:Q9HCM1	intact:EBI-2849752|uniprotkb:Q74X70	intact:EBI-308368|uniprotkb:Q4KN17|uniprotkb:Q9NVL6|uniprotkb:Q9NWP9|uniprotkb:B2RTU5|ensembl:ENSP00000310338.4	psi-mi:q8d1d2_yerpe(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:y0687(locus name)	psi-mi:resf1_human(display_long)|uniprotkb:RESF1(gene name)|psi-mi:RESF1(display_short)|uniprotkb:C12orf35(gene name synonym)|uniprotkb:KIAA1551(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873271|imex:IM-13779-8026	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010214(Transcription termination factor NusA, C-terminal duplication)|interpro:IPR010213(Transcription termination factor NusA)|interpro:IPR025249|interpro:IPR030842|go:""GO:0000166""(nucleotide binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|interpro:IPR036555"	"refseq:NP_060639.3|ensembl:ENSG00000174718.12(gene)|ensembl:ENST00000312561.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0042393""(histone binding)|go:""GO:0141005""(transposable element silencing by heterochromatin formation)|go:""GO:1990226""(histone methyltransferase binding)|interpro:IPR027866|mint:Q9HCM1|refseq:XP_005253462.1|refseq:XP_011519024.1|refseq:XP_016875039.1|dip:DIP-37599N|panther:PTHR21604(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YzZfDXwWbJbXKFeHL1SADDhW96Q632	rogid:JZhTz9sIotvCEoYh1IrFDhM5KzE9606	intact-crc:5367CF2FA5103352|rigid:JvUg3f/xeTDNL89tXMCUMlOM83w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCM1	uniprotkb:Q8ZIH1	intact:EBI-308368|uniprotkb:Q4KN17|uniprotkb:Q9NVL6|uniprotkb:Q9NWP9|uniprotkb:B2RTU5|ensembl:ENSP00000310338.4	intact:EBI-2841326|uniprotkb:Q0WJD6	psi-mi:resf1_human(display_long)|uniprotkb:RESF1(gene name)|psi-mi:RESF1(display_short)|uniprotkb:C12orf35(gene name synonym)|uniprotkb:KIAA1551(gene name synonym)	psi-mi:leud_yerpe(display_long)|uniprotkb:leuD(gene name)|psi-mi:leuD(display_short)|uniprotkb:Alpha-IPM isomerase(gene name synonym)|uniprotkb:Isopropylmalate isomerase(gene name synonym)|uniprotkb:YPO0530(locus name)|uniprotkb:y3648(locus name)|uniprotkb:YP_3652(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873292|imex:IM-13779-8023	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060639.3|ensembl:ENSG00000174718.12(gene)|ensembl:ENST00000312561.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0042393""(histone binding)|go:""GO:0141005""(transposable element silencing by heterochromatin formation)|go:""GO:1990226""(histone methyltransferase binding)|interpro:IPR027866|mint:Q9HCM1|refseq:XP_005253462.1|refseq:XP_011519024.1|refseq:XP_016875039.1|dip:DIP-37599N|panther:PTHR21604(orthology-group)"	"interpro:IPR004431(3-isopropylmalate dehydratase, small subunit region)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|go:""GO:0003861""(3-isopropylmalate dehydratase activity)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009316""(3-isopropylmalate dehydratase complex)|refseq:WP_002210456.1|refseq:YP_002345602.1|interpro:IPR033940|interpro:IPR050075|panther:PTHR43345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JZhTz9sIotvCEoYh1IrFDhM5KzE9606	rogid:lF0EK380WhlR7ondVqFIwVAnDFQ632	intact-crc:8322E491A5F6B6CE|rigid:U4R3UQPB/WrRSInwLq0hayWHkLE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCM1	uniprotkb:Q8D0D4	intact:EBI-308368|uniprotkb:Q4KN17|uniprotkb:Q9NVL6|uniprotkb:Q9NWP9|uniprotkb:B2RTU5|ensembl:ENSP00000310338.4	intact:EBI-2847212	psi-mi:resf1_human(display_long)|uniprotkb:RESF1(gene name)|psi-mi:RESF1(display_short)|uniprotkb:C12orf35(gene name synonym)|uniprotkb:KIAA1551(gene name synonym)	psi-mi:q8d0d4_yerpe(display_long)|uniprotkb:hmsH(gene name)|psi-mi:hmsH(display_short)|uniprotkb:y2359(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873278|imex:IM-13779-8022	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060639.3|ensembl:ENSG00000174718.12(gene)|ensembl:ENST00000312561.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0042393""(histone binding)|go:""GO:0141005""(transposable element silencing by heterochromatin formation)|go:""GO:1990226""(histone methyltransferase binding)|interpro:IPR027866|mint:Q9HCM1|refseq:XP_005253462.1|refseq:XP_011519024.1|refseq:XP_016875039.1|dip:DIP-37599N|panther:PTHR21604(orthology-group)"	"interpro:IPR023870|interpro:IPR011990(Tetratricopeptide-like helical)|go:""GO:1901515""(poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity)|interpro:IPR049003"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JZhTz9sIotvCEoYh1IrFDhM5KzE9606	rogid:oBs/IRM9/gKecuXNw9IoCZLu4Vw632	intact-crc:F5BABE2FA4DA3019|rigid:dAIsDhQpxXV7vdMY1xhXTP1kDBo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCM1	uniprotkb:Q8CZZ7	intact:EBI-308368|uniprotkb:Q4KN17|uniprotkb:Q9NVL6|uniprotkb:Q9NWP9|uniprotkb:B2RTU5|ensembl:ENSP00000310338.4	intact:EBI-2842831|uniprotkb:Q74W48	psi-mi:resf1_human(display_long)|uniprotkb:RESF1(gene name)|psi-mi:RESF1(display_short)|uniprotkb:C12orf35(gene name synonym)|uniprotkb:KIAA1551(gene name synonym)	psi-mi:q8czz7_yerpe(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:YP_1051(locus name)|uniprotkb:y3075(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873285|imex:IM-13779-8025	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060639.3|ensembl:ENSG00000174718.12(gene)|ensembl:ENST00000312561.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0042393""(histone binding)|go:""GO:0141005""(transposable element silencing by heterochromatin formation)|go:""GO:1990226""(histone methyltransferase binding)|interpro:IPR027866|mint:Q9HCM1|refseq:XP_005253462.1|refseq:XP_011519024.1|refseq:XP_016875039.1|dip:DIP-37599N|panther:PTHR21604(orthology-group)"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JZhTz9sIotvCEoYh1IrFDhM5KzE9606	rogid:5D57QZRbHjtu2izZZ+54f7spmuk632	intact-crc:333B8678A439C6FD|rigid:ozR9nJV0/ui2xKDbyYnPkJtekk0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IX21	uniprotkb:A0A5P8YAV7	intact:EBI-2682240|uniprotkb:Q9NPE8|uniprotkb:A8K950|uniprotkb:Q5W0L8|uniprotkb:B1AL17|uniprotkb:Q6GMU6|ensembl:ENSP00000238961.3	intact:EBI-2839792|uniprotkb:Q74QU9|uniprotkb:Q0WA24|uniprotkb:Q7CG16|uniprotkb:A0A0H2W8V3	psi-mi:slf2_human(display_long)|uniprotkb:SLF2(gene name)|psi-mi:SLF2(display_short)|uniprotkb:C10orf6(gene name synonym)|uniprotkb:FAM178A(gene name synonym)|uniprotkb:Smc5/6 localization factor 1(gene name synonym)	psi-mi:a0a5p8yav7_yerpe(display_long)|uniprotkb:pelY(gene name)|psi-mi:pelY(display_short)|uniprotkb:YPO3994(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873332|imex:IM-13779-8029	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060591.3|refseq:NP_001230699.1|refseq:NP_001129595.1|ensembl:ENSG00000119906.13(gene)|ensembl:ENST00000238961.9(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006974""(DNA damage response)|go:""GO:0016605""(PML body)|go:""GO:0016925""(protein sumoylation)|go:""GO:0030915""(Smc5-Smc6 complex)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0034184""(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:""GO:0035861""(site of double-strand break)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0140588""(chromatin looping)|go:""GO:1990166""(protein localization to site of double-strand break)|go:""GO:2000781""(positive regulation of double-strand break repair)|interpro:IPR026161|interpro:IPR044276|mint:Q8IX21|rcsb pdb:7T5P|panther:PTHR16046(orthology-group)"	"interpro:IPR010702(Periplasmic pectate lyase)|refseq:YP_002348864.1|refseq:WP_002209555.1|go:""GO:0016837""(carbon-oxygen lyase activity, acting on polysaccharides)|go:""GO:0042597""(periplasmic space)|go:""GO:0045490""(pectin catabolic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Rf8vnUtDelcFN0qcbmtvHWn2z0c9606	rogid:TdSmcoWgW+r5eNyU5ieC4Vae68s632	intact-crc:E333AFA18C8D7A84|rigid:6OhMP/X8Pm6HhHDtHqyiEAn20TA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96JB5	uniprotkb:A0A2U2H415	intact:EBI-718818|uniprotkb:Q53FA2|uniprotkb:Q9H3F8|uniprotkb:Q9H8G0|uniprotkb:Q9HBR9|uniprotkb:D3DTU1|uniprotkb:D3DTU2|ensembl:ENSP00000344683.4|uniprotkb:B7Z6N4|uniprotkb:F5H3I5	intact:EBI-2873313|uniprotkb:Q74WE5|uniprotkb:A0A0H2W2L6|uniprotkb:Q7CH92|uniprotkb:A0A384L4C9|uniprotkb:A0A380PMX3	psi-mi:ck5p3_human(display_long)|uniprotkb:CDK5 activator-binding protein C53(gene name synonym)|uniprotkb:Protein HSF-27(gene name synonym)|uniprotkb:CDK5RAP3(gene name)|psi-mi:CDK5RAP3(display_short)|uniprotkb:IC53(gene name synonym)|uniprotkb:MSTP016(orf name)|uniprotkb:OK/SW-cl.114(orf name)|uniprotkb:PP1553(orf name)|uniprotkb:LXXLL/leucine-zipper-containing ARF-binding protein(gene name synonym)|uniprotkb:LZAP(gene name synonym)	psi-mi:a0a2u2h415_yerpe(display_long)|uniprotkb:tyrP(gene name)|psi-mi:tyrP(display_short)|uniprotkb:YPO1209(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873318|imex:IM-13779-8030	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_788276.1|refseq:NP_001265126.1|ensembl:ENSG00000108465.15(gene)|ensembl:ENST00000338399.9(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0001889""(liver development)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0007420""(brain development)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010921""(regulation of phosphatase activity)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030262""(apoptotic nuclear changes)|go:""GO:0030332""(cyclin binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0044818""(mitotic G2/M transition checkpoint)|go:""GO:0045664""(regulation of neuron differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0060318""(definitive erythrocyte differentiation)|go:""GO:0071569""(protein ufmylation)|go:""GO:0071901""(negative regulation of protein serine/threonine kinase activity)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:0140501""(positive regulation of reticulophagy)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1901798""(positive regulation of signal transduction by p53 class mediator)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR008491(Protein of unknown function DUF773)|mint:Q96JB5|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8QFC|refseq:NP_001265127.1|refseq:NP_001265145.1|refseq:NP_001265146.1|refseq:XP_011523599.1|refseq:XP_016880653.1|refseq:XP_016880654.1|panther:PTHR14894(orthology-group)"	"interpro:IPR013059(Tryptophan/tyrosine transporter)|interpro:IPR018227|interpro:IPR013061(Tryptophan/tryrosine permease, conserved site)|refseq:WP_002221775.1|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005886""(plasma membrane)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|refseq:YP_002346243.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:K1S/DQ6fYeOm+MiiGicED0chJAw9606	rogid:/A7SqYiTOhFwLlDqB8yiPbScMvc632	intact-crc:8ED7AACCA0575C45|rigid:j5ht0C4EVlNXesnL4j/xZygvSzM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96JB5	uniprotkb:A0A3N4B652	intact:EBI-718818|uniprotkb:Q53FA2|uniprotkb:Q9H3F8|uniprotkb:Q9H8G0|uniprotkb:Q9HBR9|uniprotkb:D3DTU1|uniprotkb:D3DTU2|ensembl:ENSP00000344683.4|uniprotkb:B7Z6N4|uniprotkb:F5H3I5	intact:EBI-2841456|uniprotkb:Q74UD2|uniprotkb:A0A0H2W5A2|uniprotkb:Q7CIY7	psi-mi:ck5p3_human(display_long)|uniprotkb:CDK5 activator-binding protein C53(gene name synonym)|uniprotkb:Protein HSF-27(gene name synonym)|uniprotkb:CDK5RAP3(gene name)|psi-mi:CDK5RAP3(display_short)|uniprotkb:IC53(gene name synonym)|uniprotkb:MSTP016(orf name)|uniprotkb:OK/SW-cl.114(orf name)|uniprotkb:PP1553(orf name)|uniprotkb:LXXLL/leucine-zipper-containing ARF-binding protein(gene name synonym)|uniprotkb:LZAP(gene name synonym)	psi-mi:a0a3n4b652_yerpe(display_long)|uniprotkb:cheA(gene name)|psi-mi:cheA(display_short)|uniprotkb:YPO1666(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873306|imex:IM-13779-8027	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_788276.1|refseq:NP_001265126.1|ensembl:ENSG00000108465.15(gene)|ensembl:ENST00000338399.9(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0001889""(liver development)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0007420""(brain development)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010921""(regulation of phosphatase activity)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030262""(apoptotic nuclear changes)|go:""GO:0030332""(cyclin binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0044818""(mitotic G2/M transition checkpoint)|go:""GO:0045664""(regulation of neuron differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0060318""(definitive erythrocyte differentiation)|go:""GO:0071569""(protein ufmylation)|go:""GO:0071901""(negative regulation of protein serine/threonine kinase activity)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:0140501""(positive regulation of reticulophagy)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1901798""(positive regulation of signal transduction by p53 class mediator)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR008491(Protein of unknown function DUF773)|mint:Q96JB5|rcsb pdb:8OHD|rcsb pdb:8OJ0|rcsb pdb:8OJ5|rcsb pdb:8QFC|refseq:NP_001265127.1|refseq:NP_001265145.1|refseq:NP_001265146.1|refseq:XP_011523599.1|refseq:XP_016880653.1|refseq:XP_016880654.1|panther:PTHR14894(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR002545(CheW-like protein)|interpro:IPR015162(CheY binding)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR008207(""Signal transduction histidine kinase, phosphotransfer (Hpt) region"")|interpro:IPR004105(Signal transduction histidine kinase, subgroup, homodimeric)|interpro:IPR005467(Signal transduction histidine kinase, core)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006935""(chemotaxis)|refseq:YP_002346673.1|interpro:IPR035891|interpro:IPR036061|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037006|interpro:IPR051315|panther:PTHR43395(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:K1S/DQ6fYeOm+MiiGicED0chJAw9606	rogid:KztfI7bmNuR6U1Zo6bOZct0DtBc632	intact-crc:1C59EF92CDA1E550|rigid:jYxBMIg08RsMPGe07Em1XFqSqkI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKN0	uniprotkb:Q8IX21	intact:EBI-2845390	intact:EBI-2682240|uniprotkb:Q9NPE8|uniprotkb:A8K950|uniprotkb:Q5W0L8|uniprotkb:B1AL17|uniprotkb:Q6GMU6|ensembl:ENSP00000238961.3	psi-mi:q8ckn0_yerpe(display_long)|uniprotkb:y3261(locus name)	psi-mi:slf2_human(display_long)|uniprotkb:SLF2(gene name)|psi-mi:SLF2(display_short)|uniprotkb:C10orf6(gene name synonym)|uniprotkb:FAM178A(gene name synonym)|uniprotkb:Smc5/6 localization factor 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873325|imex:IM-13779-8028	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR009241(Protein of unknown function DUF891)	"refseq:NP_060591.3|refseq:NP_001230699.1|refseq:NP_001129595.1|ensembl:ENSG00000119906.13(gene)|ensembl:ENST00000238961.9(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006974""(DNA damage response)|go:""GO:0016605""(PML body)|go:""GO:0016925""(protein sumoylation)|go:""GO:0030915""(Smc5-Smc6 complex)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0034184""(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:""GO:0035861""(site of double-strand break)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0140588""(chromatin looping)|go:""GO:1990166""(protein localization to site of double-strand break)|go:""GO:2000781""(positive regulation of double-strand break repair)|interpro:IPR026161|interpro:IPR044276|mint:Q8IX21|rcsb pdb:7T5P|panther:PTHR16046(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SE+YZBFvvwyvu5gamIwWEcVlxhs632	rogid:Rf8vnUtDelcFN0qcbmtvHWn2z0c9606	intact-crc:49EFAB190D5E1F8F|rigid:6AQcJq/KnoXzKvqrnt06O9OmHEU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULV3	uniprotkb:Q8CLQ8	intact:EBI-2652948|uniprotkb:Q9NYM8|uniprotkb:Q9UHK4|uniprotkb:Q9Y3F9|uniprotkb:Q9Y3G0|uniprotkb:Q5SYW5|uniprotkb:Q5SYW3|uniprotkb:Q8WU72|uniprotkb:Q9H868|uniprotkb:A8K9J8|uniprotkb:B4E131|uniprotkb:B7ZAS8|ensembl:ENSP00000362029.5|ensembl:ENSP00000489425.1	intact:EBI-2873342	psi-mi:ciz1_human(display_long)|uniprotkb:CIZ1(gene name)|psi-mi:CIZ1(display_short)|uniprotkb:LSFR1(gene name synonym)|uniprotkb:NP94(gene name synonym)|uniprotkb:ZNF356(gene name synonym)|uniprotkb:CDKN1A-interacting zinc finger protein 1(gene name synonym)|uniprotkb:Nuclear protein NP94(gene name synonym)|uniprotkb:Zinc finger protein 356(gene name synonym)	psi-mi:q8clq8_yerpe(display_long)|uniprotkb:y0552(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873339|imex:IM-13779-8031	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:420492""|mint:Q9ULV3|rcsb pdb:7X39|ensembl:ENSG00000148337.22(gene)|ensembl:ENST00000372938.10(transcript)|ensembl:ENST00000634901.1(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030332""(cyclin binding)|go:""GO:0032298""(positive regulation of DNA-templated DNA replication initiation)|go:""GO:0051457""(maintenance of protein location in nucleus)|go:""GO:0060816""(random inactivation of X chromosome)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR026811|interpro:IPR036236|refseq:NP_001124487.1|refseq:NP_001124488.1|refseq:NP_001124489.1|refseq:NP_001124490.1|refseq:NP_001244904.1|refseq:NP_001244905.1|refseq:NP_036259.2|refseq:XP_005251945.2|refseq:XP_005251948.2|refseq:XP_005251950.4|refseq:XP_006717102.2|refseq:XP_016870085.1|panther:PTHR15491(orthology-group)"	"interpro:IPR023214|interpro:IPR024197|interpro:IPR036412|go:""GO:0046872""(metal ion binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZjDQwT+PexCvP7x2bIAZn9nYepc9606	rogid:Qz/RmtxarSMQb5ce+N3MH7NAenY632	intact-crc:8B1D85B0032A1A51|rigid:c/vSmlZtfVHR2wbVQnMLwqRhImM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0N9	uniprotkb:Q86X95	intact:EBI-2845331|uniprotkb:Q74UJ0	intact:EBI-627102|uniprotkb:A6NFI6|uniprotkb:A8K8M4|uniprotkb:O95367|uniprotkb:Q12804|uniprotkb:Q4G1B9|uniprotkb:Q6PJI4|uniprotkb:Q8IWI2|ensembl:ENSP00000339723.3	psi-mi:q8d0n9_yerpe(display_long)|uniprotkb:pqiB2(gene name)|psi-mi:pqiB2(display_short)|uniprotkb:YP_1726(locus name)|uniprotkb:y1863(locus name)	psi-mi:cir1_human(display_long)|uniprotkb:CIR(gene name synonym)|uniprotkb:CBF1-interacting corepressor(gene name synonym)|uniprotkb:Recepin(gene name synonym)|uniprotkb:CIR1(gene name)|psi-mi:CIR1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873356|imex:IM-13779-8032	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003399(Mammalian cell entry related)|go:""GO:0016020""(membrane)|interpro:IPR051800"	"refseq:NP_004873.3|ensembl:ENSG00000138433.16(gene)|ensembl:ENST00000342016.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0019901""(protein kinase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR019339|interpro:IPR040014|mint:Q86X95|rcsb pdb:6ZYM|rcsb pdb:8I0W|panther:PTHR13151(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ubTQpOsKz5MxAzZCDHdFKkWSofo632	rogid:DMnBG746eQpvLsf9D+lgeUKnni09606	intact-crc:4F65CEBB1B73E2A1|rigid:AtfFle1UeaSpBLO4XrIsbUuc4S0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULV3	uniprotkb:A0A0H2W496	intact:EBI-2652948|uniprotkb:Q9NYM8|uniprotkb:Q9UHK4|uniprotkb:Q9Y3F9|uniprotkb:Q9Y3G0|uniprotkb:Q5SYW5|uniprotkb:Q5SYW3|uniprotkb:Q8WU72|uniprotkb:Q9H868|uniprotkb:A8K9J8|uniprotkb:B4E131|uniprotkb:B7ZAS8|ensembl:ENSP00000362029.5|ensembl:ENSP00000489425.1	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	psi-mi:ciz1_human(display_long)|uniprotkb:CIZ1(gene name)|psi-mi:CIZ1(display_short)|uniprotkb:LSFR1(gene name synonym)|uniprotkb:NP94(gene name synonym)|uniprotkb:ZNF356(gene name synonym)|uniprotkb:CDKN1A-interacting zinc finger protein 1(gene name synonym)|uniprotkb:Nuclear protein NP94(gene name synonym)|uniprotkb:Zinc finger protein 356(gene name synonym)	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873349|imex:IM-13779-8036	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:420492""|mint:Q9ULV3|rcsb pdb:7X39|ensembl:ENSG00000148337.22(gene)|ensembl:ENST00000372938.10(transcript)|ensembl:ENST00000634901.1(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030332""(cyclin binding)|go:""GO:0032298""(positive regulation of DNA-templated DNA replication initiation)|go:""GO:0051457""(maintenance of protein location in nucleus)|go:""GO:0060816""(random inactivation of X chromosome)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR026811|interpro:IPR036236|refseq:NP_001124487.1|refseq:NP_001124488.1|refseq:NP_001124489.1|refseq:NP_001124490.1|refseq:NP_001244904.1|refseq:NP_001244905.1|refseq:NP_036259.2|refseq:XP_005251945.2|refseq:XP_005251948.2|refseq:XP_005251950.4|refseq:XP_006717102.2|refseq:XP_016870085.1|panther:PTHR15491(orthology-group)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZjDQwT+PexCvP7x2bIAZn9nYepc9606	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	intact-crc:3FD4E28B56DC36C4|rigid:fOVaSRJA3mTfZjJGQs4B1JiBgB4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WAP0	uniprotkb:Q14011	intact:EBI-2839765|uniprotkb:Q74R13|uniprotkb:Q8D1H9	intact:EBI-538850|intact:EBI-10980353|uniprotkb:B3KT17|uniprotkb:B4E2X2|ensembl:ENSP00000322887.4|ensembl:ENSP00000465779.1|ensembl:ENSP00000466110.1|ensembl:ENSP00000466207.1|ensembl:ENSP00000468788.1	psi-mi:ubid_yerpe(display_long)|uniprotkb:ubiD(gene name)|psi-mi:ubiD(display_short)|uniprotkb:Polyprenyl p-hydroxybenzoate decarboxylase(gene name synonym)|uniprotkb:YPO3769(locus name)|uniprotkb:y0461(locus name)|uniprotkb:YP_3279(locus name)	psi-mi:cirbp_human(display_long)|uniprotkb:Glycine-rich RNA-binding protein CIRP(gene name synonym)|uniprotkb:A18 hnRNP(gene name synonym)|uniprotkb:CIRBP(gene name)|psi-mi:CIRBP(display_short)|uniprotkb:A18HNRNP(gene name synonym)|uniprotkb:CIRP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873363|imex:IM-13779-8035	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002830(Carboxylyase-related)|interpro:IPR023677|refseq:YP_002348648.1|interpro:IPR048304|interpro:IPR049381|interpro:IPR049383|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0008694""(3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002215917.1|panther:PTHR30108(orthology-group)"	"refseq:NP_001271.1|refseq:XP_006722700.1|refseq:NP_001287744.1|refseq:NP_001287758.1|panther:PTHR48034(orthology-group)|ensembl:ENSG00000099622.14(gene)|ensembl:ENST00000320936.9(transcript)|ensembl:ENST00000585630.5(transcript)|ensembl:ENST00000586472.5(transcript)|ensembl:ENST00000588030.5(transcript)|ensembl:ENST00000588090.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0009409""(response to cold)|go:""GO:0009411""(response to UV)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030371""(translation repressor activity)|go:""GO:0034063""(stress granule assembly)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0070181""(small ribosomal subunit rRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034278|interpro:IPR035979|interpro:IPR050441|mint:Q14011|rcsb pdb:1X5S|rcsb pdb:5TBX|rcsb pdb:8CMK"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6T5bdpfVWr02Z+TIui0xRWwmcUs632	rogid:nm6/8k5Pw1AnoXsSw9cazJkL49U9606	intact-crc:E76EF9278EE8685A|rigid:iVtbPzUyoA1mUUq7WepuyemB9u4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PBF6	uniprotkb:Q969X6	intact:EBI-2858208|uniprotkb:Q74RW5|uniprotkb:Q7CGC7|uniprotkb:A0A3N4BUB9|uniprotkb:Q0WJ85	intact:EBI-2602591|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13|ensembl:ENSP00000327179.7|ensembl:ENSP00000458843.2	psi-mi:a0a2s9pbf6_yerpe(display_long)|uniprotkb:uxaA(gene name)|psi-mi:uxaA(display_short)|uniprotkb:YPO0581(locus name)	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873370|imex:IM-13779-8033	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007392(D-galactarate dehydratase/Altronate hydrolase, C-terminal)|interpro:IPR013974(SAF domain)|interpro:IPR044144|interpro:IPR052172|refseq:WP_002210408.1|go:""GO:0016787""(hydrolase activity)|go:""GO:0016829""(lyase activity)|interpro:IPR048332|refseq:YP_002345653.1"	"ensembl:ENSG00000141076.18(gene)|ensembl:ENSG00000262788.3(gene)|ensembl:ENST00000314423.12(transcript)|ensembl:ENST00000575702.3(transcript)|go:""GO:0000462""(""maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0001650""(fibrillar center)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0030490""(maturation of SSU-rRNA)|go:""GO:0030686""(90S preribosome)|go:""GO:0032040""(small-subunit processome)|go:""GO:0034455""(t-UTP complex)|go:""GO:0042274""(ribosomal small subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR046351|mint:Q969X6|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2|efo:""Orphanet:168583""|panther:PTHR44163(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HPdHp8PXEzf8Z8gFJJj/FAsINEk632	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	intact-crc:CEAB4057C19DAFAA|rigid:m9cvSBx9+ZDbpQ/od/snxJNb9yc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15642	uniprotkb:A0A5P8YEZ8	intact:EBI-739936|uniprotkb:O15184|uniprotkb:Q53G22|uniprotkb:Q5TZN1|uniprotkb:Q6FI24|uniprotkb:Q8NFL1|uniprotkb:Q8TCY1|uniprotkb:Q8TDX3|uniprotkb:Q96RJ1|uniprotkb:B2R8A6|uniprotkb:B7WP22|uniprotkb:D6W645|ensembl:ENSP00000320117.7|intact:EBI-28977062	intact:EBI-2845602|uniprotkb:Q74U77|uniprotkb:Q0WFE2|uniprotkb:Q7CIA0|uniprotkb:A0A384LA14	psi-mi:cip4_human(display_long)|uniprotkb:TRIP10(gene name)|psi-mi:TRIP10(display_short)|uniprotkb:CIP4(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 10(gene name synonym)|uniprotkb:Protein Felic(gene name synonym)|uniprotkb:Salt tolerant protein(gene name synonym)|uniprotkb:STOT(gene name synonym)|uniprotkb:STP(gene name synonym)	psi-mi:a0a5p8yez8_yerpe(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:YPO2010(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873377|imex:IM-13779-8034	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004231.1|refseq:NP_001275891.1|refseq:NP_001275892.1|ensembl:ENSG00000125733.18(gene)|ensembl:ENST00000313244.14(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005938""(cell cortex)|go:""GO:0006897""(endocytosis)|go:""GO:0007154""(cell communication)|go:""GO:0007165""(signal transduction)|go:""GO:0008289""(lipid binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0042802""(identical protein binding)|go:""GO:0042995""(cell projection)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|mint:Q15642|rcsb pdb:2CT4|rcsb pdb:2EFK|rcsb pdb:2KE4|reactome:R-HSA-8856828|reactome:R-HSA-9013406|dip:DIP-39840N|panther:PTHR15735(orthology-group)"	"interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|interpro:IPR004095(TGS)|interpro:IPR031167|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0043023""(ribosomal large subunit binding)|interpro:IPR041706|refseq:WP_002211245.1|refseq:YP_002346996.1|panther:PTHR23305(orthology-group)"	"psi-mi:""MI:0469""(intact)"	crc64:A9BFE85520C7ABC5	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:6DvFGTlXvKhqvKlLcV1sRucCKzo9606	rogid:3iq6UNiclH9s/Tvlmo7cFMlj60w632	intact-crc:A0F71469E6AFE659|rigid:uwCAgtelM3Bsizhwy99YlJn60Pc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YHQ6	uniprotkb:Q9NPC3	intact:EBI-2864330|uniprotkb:Q74VQ5|uniprotkb:A0A0H2W376|uniprotkb:Q7CHH7|uniprotkb:A0A384KJY0	intact:EBI-745269|ensembl:ENSP00000337396.4|ensembl:ENSP00000351810.4|ensembl:ENSP00000381226.2|ensembl:ENSP00000381229.2|ensembl:ENSP00000381235.3|ensembl:ENSP00000517311.1|ensembl:ENSP00000517312.1|ensembl:ENSP00000517313.1|ensembl:ENSP00000517314.1|ensembl:ENSP00000517315.1|ensembl:ENSP00000517316.1	psi-mi:a0a5p8yhq6_yerpe(display_long)|uniprotkb:YPO1356(locus name)	psi-mi:cip1_human(display_long)|uniprotkb:Cyclin-B1-interacting protein 1(gene name synonym)|uniprotkb:Human enhancer of invasion 10(gene name synonym)|uniprotkb:CCNB1IP1(gene name)|psi-mi:CCNB1IP1(display_short)|uniprotkb:C14orf18(gene name synonym)|uniprotkb:HEI10(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CCNB1IP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873384|imex:IM-13779-8037	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR021295|refseq:WP_002211363.1|interpro:IPR036291|refseq:YP_002346379.1|panther:PTHR43000(orthology-group)	"refseq:NP_067001.3|refseq:NP_878269.1|refseq:NP_878272.1|ensembl:ENSG00000100814.19(gene)|ensembl:ENSG00000291784.1(gene)|ensembl:ENST00000353689.8(transcript)|ensembl:ENST00000358932.9(transcript)|ensembl:ENST00000398160.6(transcript)|ensembl:ENST00000398163.6(transcript)|ensembl:ENST00000398169.7(transcript)|ensembl:ENST00000708737.1(transcript)|ensembl:ENST00000708738.1(transcript)|ensembl:ENST00000708739.1(transcript)|ensembl:ENST00000708740.1(transcript)|ensembl:ENST00000708741.1(transcript)|ensembl:ENST00000708742.1(transcript)|go:""GO:0000795""(synaptonemal complex)|go:""GO:0001825""(blastocyst formation)|go:""GO:0007131""(reciprocal meiotic recombination)|go:""GO:0007286""(spermatid development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051026""(chiasma assembly)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR042448|panther:PTHR14305(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:odiUhCU2SdvAlCgMVLoT5omirwE632	rogid:UyF392Md+IuOz5wp9kW2Pjr2ZzY9606	intact-crc:6201A54F396EBF20|rigid:9g54yvB6ZpiRhy2ua76K6wgjY5A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZK9	uniprotkb:Q99653	intact:EBI-2873408|uniprotkb:Q74QX0	intact:EBI-722721|uniprotkb:Q6FHZ9|uniprotkb:B2R6H9|intact:EBI-25599384|ensembl:ENSP00000335632.5	psi-mi:q8czk9_yerpe(display_long)|uniprotkb:gdhA(gene name)|psi-mi:gdhA(display_short)|uniprotkb:y3858(locus name)	psi-mi:chp1_human(display_long)|uniprotkb:CHP1(gene name)|psi-mi:CHP1(display_short)|uniprotkb:CHP(gene name synonym)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873405|imex:IM-13779-8038	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR014362(Glutamate dehydrogenase)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|go:""GO:0000166""(nucleotide binding)|go:""GO:0004353""(""glutamate dehydrogenase [NAD(P)+] activity"")|go:""GO:0006520""(amino acid metabolic process)|interpro:IPR050724|interpro:IPR046346"	"refseq:NP_009167.1|ensembl:ENSG00000187446.12(gene)|ensembl:ENST00000334660.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001578""(microtubule bundle formation)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006813""(potassium ion transport)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008017""(microtubule binding)|go:""GO:0010923""(negative regulation of phosphatase activity)|go:""GO:0015385""(""sodium:proton antiporter activity"")|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0019900""(kinase binding)|go:""GO:0022406""(membrane docking)|go:""GO:0030133""(transport vesicle)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031953""(negative regulation of protein autophosphorylation)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032417""(""positive regulation of sodium:proton antiporter activity"")|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0045121""(membrane raft)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051222""(positive regulation of protein transport)|go:""GO:0051453""(regulation of intracellular pH)|go:""GO:0060050""(positive regulation of protein glycosylation)|go:""GO:0061024""(membrane organization)|go:""GO:0061025""(membrane fusion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0071073""(positive regulation of phospholipid biosynthetic process)|go:""GO:0071468""(cellular response to acidic pH)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:1990351""(transporter complex)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR051875|mint:Q99653|rcsb pdb:2E30|rcsb pdb:7DSV|rcsb pdb:7DSX|rcsb pdb:7X2U|reactome:R-HSA-2160916|panther:PTHR46002(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OJoOfooxyJChLTkX1xVP5nX2sqA632	rogid:6/VeERuA4F0QeWlUj0pN8u0E6hc9606	intact-crc:F9B5469924DAF7D7|rigid:QHGx06rp03MzHiziH3EX1s3uyns	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6M0NNK5	uniprotkb:Q7LBR1	intact:EBI-2846580	intact:EBI-2118090|uniprotkb:Q96E89|uniprotkb:Q9HD41|ensembl:ENSP00000432279.1	psi-mi:a0a6m0nnk5_yerpe(display_long)|uniprotkb:y1846(locus name)	psi-mi:chm1b_human(display_long)|uniprotkb:CHMP1B(gene name)|psi-mi:CHMP1B(display_short)|uniprotkb:C18orf2(gene name synonym)|uniprotkb:Chromatin-modifying protein 1b(gene name synonym)|uniprotkb:CHMP1.5(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 46-2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873417|imex:IM-13779-8039	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T7I9(uniprot-removed-ac)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR008640(Hep/Hag)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0019867""(outer membrane)"	"refseq:NP_065145.2|panther:PTHR10476(orthology-group)|dip:DIP-48534N|ensembl:ENSG00000255112.3(gene)|ensembl:ENST00000526991.3(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0000776""(kinetochore)|go:""GO:0000815""(ESCRT III complex)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005771""(multivesicular body)|go:""GO:0005828""(kinetochore microtubule)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006914""(autophagy)|go:""GO:0006997""(nucleus organization)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0010008""(endosome membrane)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015031""(protein transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030117""(membrane coat)|go:""GO:0030496""(midbody)|go:""GO:0031468""(nuclear membrane reassembly)|go:""GO:0032509""(endosome transport via multivesicular body sorting pathway)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045324""(late endosome to vacuole transport)|go:""GO:0046761""(viral budding from plasma membrane)|go:""GO:0051301""(cell division)|go:""GO:0051469""(vesicle fusion with vacuole)|go:""GO:0061763""(multivesicular body-lysosome fusion)|go:""GO:0061952""(midbody abscission)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071985""(multivesicular body sorting pathway)|go:""GO:0090148""(membrane fission)|go:""GO:0090541""(MIT domain binding)|go:""GO:0097352""(autophagosome maturation)|go:""GO:1901673""(regulation of mitotic spindle assembly)|go:""GO:1902774""(late endosome to lysosome transport)|go:""GO:1904903""(ESCRT III complex disassembly)|go:""GO:1904930""(amphisome membrane)|interpro:IPR005024(Snf7)|mint:Q7LBR1|rcsb pdb:3EAB|rcsb pdb:3JC1|rcsb pdb:4TXQ|rcsb pdb:4TXR|rcsb pdb:6E8G|rcsb pdb:6TZ4|rcsb pdb:6TZ5|rcsb pdb:6TZ9"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/22	rogid:yL2m6VTkA9R9Q4e4kurjcWXhQOY632	rogid:JBzgWtpzZ/td6JuSSCIx5xpZE7M9606	intact-crc:9E974CB4997AB6E0|rigid:4HlHgw3g4e/k0D+I6QrMXyYEp40	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCK8	uniprotkb:Q74R28	intact:EBI-1169146|uniprotkb:Q68DQ0|uniprotkb:Q8N3Z9|uniprotkb:Q8NCY4|uniprotkb:Q8TBR9|uniprotkb:Q96F26|uniprotkb:Q4G0D8|uniprotkb:Q6DKH9|uniprotkb:Q6P440|uniprotkb:Q6ZNL7|ensembl:ENSP00000451601.1|ensembl:ENSP00000495070.1|ensembl:ENSP00000495240.1	intact:EBI-2844649|uniprotkb:Q8D1I8	psi-mi:chd8_human(display_long)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym)	psi-mi:ugpc_yerpe(display_long)|uniprotkb:ugpC(gene name)|psi-mi:ugpC(display_short)|uniprotkb:YPO3793(locus name)|uniprotkb:y0437(locus name)|uniprotkb:YP_3256(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873424|imex:IM-13779-8041	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR45623(orthology-group)|dip:DIP-38021N|ensembl:ENSG00000100888.15(gene)|ensembl:ENST00000557364.6(transcript)|ensembl:ENST00000643469.1(transcript)|ensembl:ENST00000646647.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0002039""(p53 binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006397""(mRNA processing)|go:""GO:0007420""(brain development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035176""(social behavior)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042393""(histone binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045945""(positive regulation of transcription by RNA polymerase III)|go:""GO:0048565""(digestive tract development)|go:""GO:0060134""(prepulse inhibition)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071339""(MLL1 complex)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140658""(ATP-dependent chromatin remodeler activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|go:""GO:2000270""(negative regulation of fibroblast apoptotic process)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR034724|interpro:IPR037259|interpro:IPR038718|interpro:IPR049730|interpro:IPR051493|mint:Q9HCK8|rcsb pdb:2CKA|rcsb pdb:2DL6|reactome:R-HSA-3769402|refseq:NP_001164100.1|refseq:NP_065971.2|efo:""Orphanet:261229""|efo:""Orphanet:642675"""	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR040582|interpro:IPR015855(ABC transporter, maltose/maltodextrin import, MalK)|interpro:IPR027417|refseq:WP_002211523.1|go:""GO:0001407""(glycerophosphodiester transmembrane transport)|go:""GO:0005524""(ATP binding)|go:""GO:0008643""(carbohydrate transport)|go:""GO:0015430""(ABC-type glycerol-3-phosphate transporter activity)|go:""GO:0015794""(glycerol-3-phosphate transmembrane transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055052""(""ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing"")|interpro:IPR047641|refseq:YP_002348670.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR43875(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:QwADLvHNwK00OAboBtAkqaICd489606	rogid:NtRUgbRI2HE2UzUkxbSvyMnRkao632	intact-crc:DCD485D673F0BAF4|rigid:9Rzs+0r8gMTyI5dbL4tmeyOxwJo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H1F8	uniprotkb:Q86X52	intact:EBI-2847667|uniprotkb:Q74RN0|uniprotkb:Q0WIZ2|uniprotkb:Q7CGI4|uniprotkb:A0A384LC57	intact:EBI-2873391|uniprotkb:Q7LFU5|uniprotkb:Q6UX38|uniprotkb:Q9Y2J5|ensembl:ENSP00000254190.3	psi-mi:a0a2u2h1f8_yerpe(display_long)|uniprotkb:YPO0680(locus name)	psi-mi:chss1_human(display_long)|uniprotkb:CHSY1(gene name)|psi-mi:CHSY1(display_short)|uniprotkb:CHSY(gene name synonym)|uniprotkb:CSS1(gene name synonym)|uniprotkb:KIAA0990(gene name synonym)|uniprotkb:Chondroitin glucuronyltransferase 1(gene name synonym)|uniprotkb:Chondroitin synthase 1(gene name synonym)|uniprotkb:Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1(gene name synonym)|uniprotkb:N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1(gene name synonym)|uniprotkb:N-acetylgalactosaminyltransferase 1(gene name synonym)|uniprotkb:UNQ756/PRO1487(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873398|imex:IM-13779-8040	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR032816|interpro:IPR032818|refseq:WP_002212173.1|go:""GO:0005886""(plasma membrane)|refseq:YP_002345746.1|panther:PTHR30353(orthology-group)"	"ensembl:ENSG00000131873.7(gene)|ensembl:ENST00000254190.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002063""(chondrocyte development)|go:""GO:0005576""(extracellular region)|go:""GO:0009954""(proximal/distal pattern formation)|go:""GO:0016020""(membrane)|go:""GO:0030206""(obsolete chondroitin sulfate biosynthetic process)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0045880""(positive regulation of smoothened signaling pathway)|go:""GO:0046872""(metal ion binding)|go:""GO:0047238""(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:""GO:0050510""(N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity)|go:""GO:0050653""(obsolete chondroitin sulfate proteoglycan biosynthetic process, chain elongation)|go:""GO:0051923""(sulfation)|go:""GO:0060349""(bone morphogenesis)|interpro:IPR008428(Chondroitin N-acetylgalactosaminyltransferase)|interpro:IPR029044|interpro:IPR051227|mint:Q86X52|reactome:R-HSA-2022870|reactome:R-HSA-3595177|refseq:NP_055733.2|efo:""Orphanet:363417""|panther:PTHR12369(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BqFEmH35pLhf+8qQYRQH+W5Vfmg632	rogid:5abXN0fO1ZkN3AkAMJQLpirQldc9606	intact-crc:C1193B07395136B5|rigid:95Z83+PmLdW7mYrW52h+TUhe56Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H2J9	uniprotkb:Q9HCK8	intact:EBI-2848383|uniprotkb:Q74PQ2|uniprotkb:A0A3N4AWI0|uniprotkb:A0A0H2W8R5|uniprotkb:Q7CL84|uniprotkb:A0A384KY00	intact:EBI-1169146|uniprotkb:Q68DQ0|uniprotkb:Q8N3Z9|uniprotkb:Q8NCY4|uniprotkb:Q8TBR9|uniprotkb:Q96F26|uniprotkb:Q4G0D8|uniprotkb:Q6DKH9|uniprotkb:Q6P440|uniprotkb:Q6ZNL7|ensembl:ENSP00000451601.1|ensembl:ENSP00000495070.1|ensembl:ENSP00000495240.1	psi-mi:a0a2u2h2j9_yerpe(display_long)|uniprotkb:npr(gene name)|psi-mi:npr(display_short)|uniprotkb:ptsO(gene name synonym)|uniprotkb:rpoR(gene name synonym)|uniprotkb:YPO3587(locus name)|uniprotkb:Nitrogen-related HPr(gene name synonym)	psi-mi:chd8_human(display_long)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873431|imex:IM-13779-8046	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|refseq:WP_002210112.1|go:""GO:0005737""(cytoplasm)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|interpro:IPR035895|refseq:YP_002348472.1|interpro:IPR050399"	"panther:PTHR45623(orthology-group)|dip:DIP-38021N|ensembl:ENSG00000100888.15(gene)|ensembl:ENST00000557364.6(transcript)|ensembl:ENST00000643469.1(transcript)|ensembl:ENST00000646647.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0002039""(p53 binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006397""(mRNA processing)|go:""GO:0007420""(brain development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035176""(social behavior)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042393""(histone binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045945""(positive regulation of transcription by RNA polymerase III)|go:""GO:0048565""(digestive tract development)|go:""GO:0060134""(prepulse inhibition)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071339""(MLL1 complex)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140658""(ATP-dependent chromatin remodeler activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|go:""GO:2000270""(negative regulation of fibroblast apoptotic process)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR034724|interpro:IPR037259|interpro:IPR038718|interpro:IPR049730|interpro:IPR051493|mint:Q9HCK8|rcsb pdb:2CKA|rcsb pdb:2DL6|reactome:R-HSA-3769402|refseq:NP_001164100.1|refseq:NP_065971.2|efo:""Orphanet:261229""|efo:""Orphanet:642675"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:eQCcvInnov3zAs8zqt7WixL4lG8632	rogid:QwADLvHNwK00OAboBtAkqaICd489606	intact-crc:468752F1F4CFD34A|rigid:eMovRMHffZhbekICZ+T27PFzI6I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YBG4	uniprotkb:Q8TD26	intact:EBI-2844283|uniprotkb:Q0WK04|uniprotkb:Q7CKQ0|uniprotkb:A0A384LJ06	intact:EBI-1043681|uniprotkb:Q5JYQ0|uniprotkb:Q5TGZ9|uniprotkb:Q5TH00|uniprotkb:Q5TH01|uniprotkb:Q8IZR2|uniprotkb:Q8WTY0|uniprotkb:Q9H4H6|uniprotkb:Q9H6D4|uniprotkb:Q9NTT7|uniprotkb:Q9P2L1|ensembl:ENSP00000362330.3	psi-mi:a0a5p8ybg4_yerpe(display_long)|uniprotkb:YPO0302(locus name)	psi-mi:chd6_human(display_long)|uniprotkb:CHD6(gene name)|psi-mi:CHD6(display_short)|uniprotkb:CHD5(gene name synonym)|uniprotkb:KIAA1335(gene name synonym)|uniprotkb:RIGB(gene name synonym)|uniprotkb:ATP-dependent helicase CHD6(gene name synonym)|uniprotkb:Radiation-induced gene B protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873452|imex:IM-13779-8043	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR018030|interpro:IPR025885|interpro:IPR025949|interpro:IPR043142|refseq:WP_002209081.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR042186|interpro:IPR037224|refseq:YP_002345384.1|panther:PTHR30451(orthology-group)"	"efo:""Orphanet:2108""|ensembl:ENSG00000124177.16(gene)|ensembl:ENST00000373233.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042393""(histone binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140658""(ATP-dependent chromatin remodeler activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|interpro:IPR049730|interpro:IPR051493|mint:Q8TD26|rcsb pdb:2EPB|refseq:NP_115597.3|panther:PTHR45623(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:C8RweNxDibwajstM8qeNKJ2Yisg632	rogid:3OZYCM6IRFVXZHCvEycD2Ha8gKI9606	intact-crc:36B964659D34ED45|rigid:fY+xwlsMwsAbkN+zUC9fb3nxPRE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10809	uniprotkb:A0A2U2GUZ8	intact:EBI-352528|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|ensembl:ENSP00000340019.2|ensembl:ENSP00000373620.3|ensembl:ENSP00000396460.2|ensembl:ENSP00000402478.2|ensembl:ENSP00000412227.2|ensembl:ENSP00000412717.2|ensembl:ENSP00000414446.2|ensembl:ENSP00000503139.1|ensembl:ENSP00000503894.1|uniprotkb:B7Z712	intact:EBI-2858974|uniprotkb:Q74PU1|uniprotkb:A0A380PJ37|uniprotkb:Q0WJS3|uniprotkb:Q7CG32|uniprotkb:A0A384L519	psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym)|uniprotkb:Heat shock protein family D member 1(gene name synonym)	psi-mi:a0a2u2guz8_yerpe(display_long)|uniprotkb:YPO0388(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873459|imex:IM-13779-8044	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000144381.18(gene)|ensembl:ENST00000345042.6(transcript)|ensembl:ENST00000388968.8(transcript)|ensembl:ENST00000418022.2(transcript)|ensembl:ENST00000426480.2(transcript)|ensembl:ENST00000428204.6(transcript)|ensembl:ENST00000439605.2(transcript)|ensembl:ENST00000452200.6(transcript)|ensembl:ENST00000677913.1(transcript)|ensembl:ENST00000678761.1(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002039""(p53 binding)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0002842""(positive regulation of T cell mediated immune response to tumor cell)|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006457""(protein folding)|go:""GO:0006458""('de novo' protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008035""(high-density lipoprotein particle binding)|go:""GO:0008637""(apoptotic mitochondrial changes)|go:""GO:0009409""(response to cold)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030135""(coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0034186""(apolipoprotein A-I binding)|go:""GO:0034514""(mitochondrial unfolded protein response)|go:""GO:0042026""(protein refolding)|go:""GO:0042100""(B cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0042113""(B cell activation)|go:""GO:0043032""(positive regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045041""(protein import into mitochondrial intermembrane space)|go:""GO:0046696""(lipopolysaccharide receptor complex)|go:""GO:0048291""(isotype switching to IgG isotypes)|go:""GO:0050821""(protein stabilization)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0051604""(protein maturation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:0140494""(migrasome)|go:""GO:0140608""(cysteine-type endopeptidase activator activity)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1900118""(negative regulation of execution phase of apoptosis)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|rcsb pdb:7L7S|rcsb pdb:8G7J|rcsb pdb:8G7K|rcsb pdb:8G7L|rcsb pdb:8G7M|rcsb pdb:8G7N|rcsb pdb:8G7O|rcsb pdb:8U39|reactome:R-HSA-1268020|reactome:R-HSA-8869496|reactome:R-HSA-9837999|reactome:R-HSA-9841251|refseq:NP_002147.2|refseq:NP_955472.1|efo:""Orphanet:100994""|efo:""Orphanet:280288""|dip:DIP-58N|panther:PTHR45633(orthology-group)"	interpro:IPR019292|refseq:WP_002209167.1|refseq:YP_002345465.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606	rogid:KAzzgB6fVtKcGVFVzqcVYB96Yyk632	intact-crc:F0CFEB5613F5227C|rigid:H0cVSIxx00QnNyE1M+Py35i7AHM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TD26	uniprotkb:Q8D1R8	intact:EBI-1043681|uniprotkb:Q5JYQ0|uniprotkb:Q5TGZ9|uniprotkb:Q5TH00|uniprotkb:Q5TH01|uniprotkb:Q8IZR2|uniprotkb:Q8WTY0|uniprotkb:Q9H4H6|uniprotkb:Q9H6D4|uniprotkb:Q9NTT7|uniprotkb:Q9P2L1|ensembl:ENSP00000362330.3	intact:EBI-2844176	psi-mi:chd6_human(display_long)|uniprotkb:CHD6(gene name)|psi-mi:CHD6(display_short)|uniprotkb:CHD5(gene name synonym)|uniprotkb:KIAA1335(gene name synonym)|uniprotkb:RIGB(gene name synonym)|uniprotkb:ATP-dependent helicase CHD6(gene name synonym)|uniprotkb:Radiation-induced gene B protein(gene name synonym)	psi-mi:q8d1r8_yerpe(display_long)|uniprotkb:y0112(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873438|imex:IM-13779-8042	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2108""|ensembl:ENSG00000124177.16(gene)|ensembl:ENST00000373233.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042393""(histone binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140658""(ATP-dependent chromatin remodeler activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|interpro:IPR049730|interpro:IPR051493|mint:Q8TD26|rcsb pdb:2EPB|refseq:NP_115597.3|panther:PTHR45623(orthology-group)"	"interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR016639(Glutathione S-transferase, predicted)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|go:""GO:0004364""(glutathione transferase activity)|interpro:IPR040079|interpro:IPR036249|interpro:IPR036282|refseq:WP_002220229.1|interpro:IPR047047"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3OZYCM6IRFVXZHCvEycD2Ha8gKI9606	rogid:t+PPnZeaiT6XhlJXTLVuOsYXAMI632	intact-crc:434CB27C0EBEFFDE|rigid:cOM6Il8qs9Y67UUt5sVEWqkwPhQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TD26	uniprotkb:A0A3N4AWI2	intact:EBI-1043681|uniprotkb:Q5JYQ0|uniprotkb:Q5TGZ9|uniprotkb:Q5TH00|uniprotkb:Q5TH01|uniprotkb:Q8IZR2|uniprotkb:Q8WTY0|uniprotkb:Q9H4H6|uniprotkb:Q9H6D4|uniprotkb:Q9NTT7|uniprotkb:Q9P2L1|ensembl:ENSP00000362330.3	intact:EBI-2850800|uniprotkb:Q74PQ4|uniprotkb:Q0WB69|uniprotkb:Q7CL85|uniprotkb:A0A384LA61	psi-mi:chd6_human(display_long)|uniprotkb:CHD6(gene name)|psi-mi:CHD6(display_short)|uniprotkb:CHD5(gene name synonym)|uniprotkb:KIAA1335(gene name synonym)|uniprotkb:RIGB(gene name synonym)|uniprotkb:ATP-dependent helicase CHD6(gene name synonym)|uniprotkb:Radiation-induced gene B protein(gene name synonym)	psi-mi:a0a3n4awi2_yerpe(display_long)|uniprotkb:ntrA(gene name synonym)|uniprotkb:rpoN(gene name synonym)|uniprotkb:YPO3582(locus name)|uniprotkb:glnF(gene name)|psi-mi:glnF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873445|imex:IM-13779-8045	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2108""|ensembl:ENSG00000124177.16(gene)|ensembl:ENST00000373233.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0042393""(histone binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140658""(ATP-dependent chromatin remodeler activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|interpro:IPR049730|interpro:IPR051493|mint:Q8TD26|rcsb pdb:2EPB|refseq:NP_115597.3|panther:PTHR45623(orthology-group)"	"interpro:IPR000394(RNA polymerase sigma factor 54)|interpro:IPR007046(RNA polymerase sigma factor 54, core-binding)|interpro:IPR007634(RNA polymerase sigma factor 54, DNA-binding)|refseq:WP_002210115.1|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001216""(DNA-binding transcription activator activity)|go:""GO:0003677""(DNA binding)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0016987""(sigma factor activity)|interpro:IPR038709|refseq:YP_002348469.1|panther:PTHR32248(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3OZYCM6IRFVXZHCvEycD2Ha8gKI9606	rogid:zdzEhy+OLn0kaYS9XKuSOj5MMBM632	intact-crc:9D54F61DDB514EC1|rigid:ht+qSWNWN7LGW6GSFkSIsgjW+/Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61604	uniprotkb:Q8CZX0	intact:EBI-711483|ensembl:ENSP00000233893.5|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|uniprotkb:Q9UDH0	intact:EBI-2843256	psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym)|uniprotkb:Heat shock protein family E member 1(gene name synonym)	psi-mi:q8czx0_yerpe(display_long)|uniprotkb:y3221(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873493|imex:IM-13779-8048	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115541.11(gene)|ensembl:ENST00000233893.10(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0016020""(membrane)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR011032(GroES-like)|interpro:IPR018369|interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:8G7N|rcsb pdb:8G7O|reactome:R-HSA-9013408|reactome:R-HSA-9841251|refseq:NP_002148.1|panther:PTHR10772(orthology-group)"	"interpro:IPR004704(Phosphotransferase system, mannose/fructose/sorbose family IID component)|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|interpro:IPR050303"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606	rogid:qJG/9uPdua0KpEAcJ9dXeyS7Cww632	intact-crc:9C36973A91580258|rigid:/McA+NpalV+NE4a695Noh7NMHGQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61604	uniprotkb:Q7CGI0	intact:EBI-711483|ensembl:ENSP00000233893.5|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|uniprotkb:Q9UDH0	intact:EBI-2840021|uniprotkb:Q74RN4	psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym)|uniprotkb:Heat shock protein family E member 1(gene name synonym)	psi-mi:ftsp_yerpe(display_long)|uniprotkb:ftsP(gene name)|psi-mi:ftsP(display_short)|uniprotkb:YPO0673(locus name)|uniprotkb:YP_2989(locus name)|uniprotkb:y3504(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873507|imex:IM-13779-8051	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115541.11(gene)|ensembl:ENST00000233893.10(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0016020""(membrane)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR011032(GroES-like)|interpro:IPR018369|interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:8G7N|rcsb pdb:8G7O|reactome:R-HSA-9013408|reactome:R-HSA-9841251|refseq:NP_002148.1|panther:PTHR10772(orthology-group)"	"refseq:YP_002345741.1|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR008972(Cupredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR026589|refseq:WP_002212176.1|go:""GO:0005507""(copper ion binding)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|interpro:IPR045087|panther:PTHR11709(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606	rogid:JQTwQ8R/Yza07pQepCvAhD8UkWA632	intact-crc:1C530EC34E5D9757|rigid:7d0AkRxjWnMv/rqfVrHRsqCDG2c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CJ05	uniprotkb:Q15782	intact:EBI-2873473|uniprotkb:Q74UG4	intact:EBI-2873481|uniprotkb:Q96F97|uniprotkb:Q5VUV7|uniprotkb:Q15783|uniprotkb:Q15749|uniprotkb:B4DPR7|uniprotkb:A6NNY3|ensembl:ENSP00000358763.4|ensembl:ENSP00000437082.1	psi-mi:q7cj05_yerpe(display_long)|uniprotkb:lolE(gene name)|psi-mi:lolE(display_short)|uniprotkb:YPO1628(locus name)	psi-mi:ch3l2_human(display_long)|uniprotkb:CHI3L2(gene name)|psi-mi:CHI3L2(display_short)|uniprotkb:Chondrocyte protein 39(gene name synonym)|uniprotkb:YKL-39(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873478|imex:IM-13779-8050	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011925(Lipoprotein releasing system, transmembrane protein, LolC/E family)|interpro:IPR011926(Lipoprotein releasing system, transmembrane protein LolE)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|go:""GO:0042953""(lipoprotein transport)|go:""GO:0044874""(lipoprotein localization to outer membrane)|go:""GO:0098797""(plasma membrane protein complex)|interpro:IPR051447|refseq:YP_002346639.1|panther:PTHR30489(orthology-group)"	"refseq:NP_001020368.1|refseq:NP_001020370.1|refseq:NP_003991.2|ensembl:ENSG00000064886.14(gene)|ensembl:ENST00000369748.9(transcript)|ensembl:ENST00000445067.6(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0016787""(hydrolase activity)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR011583(Chitinase II)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR029070|interpro:IPR050314|mint:Q15782|rcsb pdb:4AY1|rcsb pdb:4P8U|rcsb pdb:4P8V|rcsb pdb:4P8W|rcsb pdb:4P8X|panther:PTHR11177(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kpZzBPfGECA+jNjJUZoZATclgkA632	rogid:/wNVpBug4/Q2QEQI3lDgW7PX6po9606	intact-crc:1CD626B8E847030F|rigid:K821Ifxu5qsKMCufLGw7OvW0MSc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GUX9	uniprotkb:P10809	intact:EBI-2841416|uniprotkb:A0A0H2W940|uniprotkb:Q74PB0|uniprotkb:A0A384LLI5|uniprotkb:Q7CFN3|uniprotkb:A0A3N4BJ32	intact:EBI-352528|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|ensembl:ENSP00000340019.2|ensembl:ENSP00000373620.3|ensembl:ENSP00000396460.2|ensembl:ENSP00000402478.2|ensembl:ENSP00000412227.2|ensembl:ENSP00000412717.2|ensembl:ENSP00000414446.2|ensembl:ENSP00000503139.1|ensembl:ENSP00000503894.1|uniprotkb:B7Z712	psi-mi:a0a2u2gux9_yerpe(display_long)|uniprotkb:YPO4108(locus name)	psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym)|uniprotkb:Heat shock protein family D member 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873466|imex:IM-13779-8047	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR041492|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002215575.1|refseq:YP_002348959.1|interpro:IPR023198|interpro:IPR036412|interpro:IPR051600"	"ensembl:ENSG00000144381.18(gene)|ensembl:ENST00000345042.6(transcript)|ensembl:ENST00000388968.8(transcript)|ensembl:ENST00000418022.2(transcript)|ensembl:ENST00000426480.2(transcript)|ensembl:ENST00000428204.6(transcript)|ensembl:ENST00000439605.2(transcript)|ensembl:ENST00000452200.6(transcript)|ensembl:ENST00000677913.1(transcript)|ensembl:ENST00000678761.1(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0002039""(p53 binding)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0002842""(positive regulation of T cell mediated immune response to tumor cell)|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006457""(protein folding)|go:""GO:0006458""('de novo' protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008035""(high-density lipoprotein particle binding)|go:""GO:0008637""(apoptotic mitochondrial changes)|go:""GO:0009409""(response to cold)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0030135""(coated vesicle)|go:""GO:0030141""(secretory granule)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0034186""(apolipoprotein A-I binding)|go:""GO:0034514""(mitochondrial unfolded protein response)|go:""GO:0042026""(protein refolding)|go:""GO:0042100""(B cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0042113""(B cell activation)|go:""GO:0043032""(positive regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045041""(protein import into mitochondrial intermembrane space)|go:""GO:0046696""(lipopolysaccharide receptor complex)|go:""GO:0048291""(isotype switching to IgG isotypes)|go:""GO:0050821""(protein stabilization)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051131""(chaperone-mediated protein complex assembly)|go:""GO:0051604""(protein maturation)|go:""GO:0051702""(biological process involved in interaction with symbiont)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:0140494""(migrasome)|go:""GO:0140608""(cysteine-type endopeptidase activator activity)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1900118""(negative regulation of execution phase of apoptosis)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|rcsb pdb:7L7S|rcsb pdb:8G7J|rcsb pdb:8G7K|rcsb pdb:8G7L|rcsb pdb:8G7M|rcsb pdb:8G7N|rcsb pdb:8G7O|rcsb pdb:8U39|reactome:R-HSA-1268020|reactome:R-HSA-8869496|reactome:R-HSA-9837999|reactome:R-HSA-9841251|refseq:NP_002147.2|refseq:NP_955472.1|efo:""Orphanet:100994""|efo:""Orphanet:280288""|dip:DIP-58N|panther:PTHR45633(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:N4DmZVhdbeJX1EvnC462dwFiaNU632	rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606	intact-crc:B15E26002C87C408|rigid:o0G/St5+TChkPW/kGDVbBzRuJVY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61604	uniprotkb:A0A380PJW4	intact:EBI-711483|ensembl:ENSP00000233893.5|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|uniprotkb:Q9UDH0	intact:EBI-2847196|uniprotkb:Q0WI94|uniprotkb:Q7CGR6	psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym)|uniprotkb:Heat shock protein family E member 1(gene name synonym)	psi-mi:a0a380pjw4_yerpe(display_long)|uniprotkb:YPO0947(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873500|imex:IM-13779-8049	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115541.11(gene)|ensembl:ENST00000233893.10(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0016020""(membrane)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR011032(GroES-like)|interpro:IPR018369|interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:8G7N|rcsb pdb:8G7O|reactome:R-HSA-9013408|reactome:R-HSA-9841251|refseq:NP_002148.1|panther:PTHR10772(orthology-group)"	"interpro:IPR020974|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|interpro:IPR028994|refseq:WP_002224905.1|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016740""(transferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR038383|refseq:YP_002345994.1|interpro:IPR049824"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606	rogid:3Aj0qy9DiLKc8Bx9KbIJWyE+XAM632	intact-crc:3F5A44292397334E|rigid:e/m5Ifaz0rVJVp5lxGym5CQ64f8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7L5D6	uniprotkb:A0A3N4AWI2	intact:EBI-711823|ensembl:ENSP00000265857.3|uniprotkb:A4D2Q1|uniprotkb:B3KNC7|uniprotkb:Q9UFC9|uniprotkb:Q9Y309	intact:EBI-2850800|uniprotkb:Q74PQ4|uniprotkb:Q0WB69|uniprotkb:Q7CL85|uniprotkb:A0A384LA61	psi-mi:get4_human(display_long)|uniprotkb:CEE(gene name synonym)|uniprotkb:Conserved edge-expressed protein(gene name synonym)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:CGI-20(orf name)|uniprotkb:C7orf20(gene name synonym)|uniprotkb:TRC35(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 35 kDa subunit(gene name synonym)	psi-mi:a0a3n4awi2_yerpe(display_long)|uniprotkb:ntrA(gene name synonym)|uniprotkb:rpoN(gene name synonym)|uniprotkb:YPO3582(locus name)|uniprotkb:glnF(gene name)|psi-mi:glnF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873528|imex:IM-13779-8053	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000239857.7(gene)|ensembl:ENST00000265857.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0045048""(protein insertion into ER membrane)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:6AU8|mint:Q7L5D6|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|refseq:NP_057033.2|panther:PTHR12875(orthology-group)"	"interpro:IPR000394(RNA polymerase sigma factor 54)|interpro:IPR007046(RNA polymerase sigma factor 54, core-binding)|interpro:IPR007634(RNA polymerase sigma factor 54, DNA-binding)|refseq:WP_002210115.1|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001216""(DNA-binding transcription activator activity)|go:""GO:0003677""(DNA binding)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0016987""(sigma factor activity)|interpro:IPR038709|refseq:YP_002348469.1|panther:PTHR32248(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WbZJTGrC2/fB4iOFLJYn9MIWZFA9606	rogid:zdzEhy+OLn0kaYS9XKuSOj5MMBM632	intact-crc:6A18A1BAA8F6A1CB|rigid:uLcs/dD0q2xctYJV2/LX74eHF9U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCQ2	uniprotkb:Q9BRJ6	intact:EBI-2850142|uniprotkb:Q0WCY7	intact:EBI-751612|ensembl:ENSP00000350011.5|ensembl:ENSP00000380286.3|ensembl:ENSP00000380288.2	psi-mi:pur4_yerpe(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:YPO2921(locus name)|uniprotkb:YP_2536(locus name)|uniprotkb:y1309(locus name)	psi-mi:choln_human(display_long)|uniprotkb:FP15621(orf name)|uniprotkb:C7orf50(gene name)|psi-mi:C7orf50(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873521|imex:IM-13779-8052	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR029062|refseq:WP_002211561.1|interpro:IPR040707|go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609|refseq:YP_002347851.1|panther:PTHR10099(orthology-group)"	"ensembl:ENSG00000146540.15(gene)|ensembl:ENST00000357429.10(transcript)|ensembl:ENST00000397098.8(transcript)|ensembl:ENST00000397100.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005179""(hormone activity)|go:""GO:0005615""(extracellular space)|go:""GO:0045541""(negative regulation of cholesterol biosynthetic process)|interpro:IPR019327|mint:Q9BRJ6|refseq:NP_001127867.1|refseq:NP_001127868.1|refseq:NP_001305181.1|refseq:NP_115726.1|panther:PTHR22306(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8JTbD5hWDWC5PK7sHtiOwqqdyHs632	rogid:POftCOri0Nj8YUd5Kc3nNMDb41A9606	intact-crc:466E60F403F00468|rigid:16p4XOXOCbLI/wtyCudGQ20kMA0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GUX9	uniprotkb:P61604	intact:EBI-2841416|uniprotkb:A0A0H2W940|uniprotkb:Q74PB0|uniprotkb:A0A384LLI5|uniprotkb:Q7CFN3|uniprotkb:A0A3N4BJ32	intact:EBI-711483|ensembl:ENSP00000233893.5|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|uniprotkb:Q9UDH0	psi-mi:a0a2u2gux9_yerpe(display_long)|uniprotkb:YPO4108(locus name)	psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym)|uniprotkb:Heat shock protein family E member 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873514|imex:IM-13779-8054	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR041492|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002215575.1|refseq:YP_002348959.1|interpro:IPR023198|interpro:IPR036412|interpro:IPR051600"	"ensembl:ENSG00000115541.11(gene)|ensembl:ENST00000233893.10(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0016020""(membrane)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR011032(GroES-like)|interpro:IPR018369|interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:8G7N|rcsb pdb:8G7O|reactome:R-HSA-9013408|reactome:R-HSA-9841251|refseq:NP_002148.1|panther:PTHR10772(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:N4DmZVhdbeJX1EvnC462dwFiaNU632	rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606	intact-crc:F1C18072580920D9|rigid:EGnslXuv7Wqh9SAp4bO9ChPEAk0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q74XD3	uniprotkb:Q8N1K5	intact:EBI-2855960|uniprotkb:Q8ZIY8|uniprotkb:Q0WJW4|uniprotkb:Q7CKN0	intact:EBI-2873538|uniprotkb:Q5T3C4|uniprotkb:B3KT31|uniprotkb:Q5T3C5|uniprotkb:A1L4F0|uniprotkb:B3KY07|uniprotkb:A8K7N1|uniprotkb:Q6MZT7|uniprotkb:B3KW32|uniprotkb:F5H1J9|ensembl:ENSP00000357231.2|ensembl:ENSP00000357233.2|ensembl:ENSP00000480630.2|ensembl:ENSP00000480967.1	psi-mi:cuta_yerpe(display_long)|uniprotkb:cutA(gene name)|psi-mi:cutA(display_short)|uniprotkb:YPO0346(locus name)|uniprotkb:y0604(locus name)|uniprotkb:YP_0500(locus name)	psi-mi:thms1_human(display_long)|uniprotkb:THEMIS(gene name)|psi-mi:THEMIS(display_short)|uniprotkb:C6orf190(gene name synonym)|uniprotkb:C6orf207(gene name synonym)|uniprotkb:Thymocyte-expressed molecule involved in selection(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873535|imex:IM-13779-8055	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002209122.1|interpro:IPR023700|interpro:IPR004323(Divalent ion tolerance protein, CutA1)|interpro:IPR011322(Nitrogen regulatory PII-like, alpha/beta)|rcsb pdb:3GSD|interpro:IPR015867(Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal)|go:""GO:0005507""(copper ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0010038""(response to metal ion)|refseq:YP_002345424.1|panther:PTHR23419(orthology-group)"	"refseq:XP_011534118.1|refseq:NP_001305460.1|refseq:NP_001010923.1|refseq:NP_001158157.1|refseq:NP_001158159.1|ensembl:ENSG00000172673.12(gene)|ensembl:ENSG00000275122.4(gene)|ensembl:ENST00000368248.5(transcript)|ensembl:ENST00000368250.5(transcript)|ensembl:ENST00000610842.4(transcript)|ensembl:ENST00000613862.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005911""(cell-cell junction)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0043368""(positive T cell selection)|go:""GO:0043383""(negative T cell selection)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR025946|interpro:IPR039671|mint:Q8N1K5|panther:PTHR15215(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oZ+dqE3f5QFb+ouShZmMFoGk+4Q632	rogid:eKM4Ygu2txBAaJz7ABQBLijEfos9606	intact-crc:69C57725204F1938|rigid:iyJl+K4u5q7rJzSRTkPrNwUIg+Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YB62	uniprotkb:Q5TGL8	intact:EBI-2844412|uniprotkb:Q74RA2|uniprotkb:Q0WAD3|uniprotkb:Q7CKZ7|uniprotkb:A0A0H2W7C0|uniprotkb:A0A384KQ85	intact:EBI-2873557|uniprotkb:Q86XB7|uniprotkb:Q6PGP0|uniprotkb:A8K0N3|ensembl:ENSP00000369636.5	psi-mi:a0a5p8yb62_yerpe(display_long)|uniprotkb:YPO3879(locus name)	psi-mi:pxdc1_human(display_long)|uniprotkb:PXDC1(gene name)|psi-mi:PXDC1(display_short)|uniprotkb:C6orf145(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873554|imex:IM-13779-8060	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR018030|interpro:IPR025885|interpro:IPR025949|interpro:IPR043142|refseq:WP_002211999.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR042186|interpro:IPR037224|refseq:YP_002348755.1"	"refseq:NP_899229.2|ensembl:ENSG00000168994.14(gene)|ensembl:ENST00000380283.5(transcript)|go:""GO:0035091""(phosphatidylinositol binding)|interpro:IPR036871|interpro:IPR040288|panther:PTHR31433(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LoLtCTl+KcIEJlQnZYPeOB8LOg4632	rogid:jXxFQ2z/bdZ2ZxY+oZfCZvKja4w9606	intact-crc:5E819A7E73ADE424|rigid:GC4cP4ax/uYnOIwY18jLhxO270g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6K0	uniprotkb:A0A384KHP8	intact:EBI-1237183|uniprotkb:Q69YJ9|uniprotkb:Q9P0Y8|ensembl:ENSP00000349696.4|ensembl:ENSP00000441980.1	intact:EBI-2840740|uniprotkb:Q74S58|uniprotkb:Q0WHX7|uniprotkb:Q7CH24	psi-mi:cept1_human(display_long)|uniprotkb:CEPT1(gene name)|psi-mi:CEPT1(display_short)|uniprotkb:1-alkenyl-2-acylglycerol choline phosphotransferase(gene name synonym)|uniprotkb:PRO1101(orf name)	psi-mi:a0a384khp8_yerpe(display_long)|uniprotkb:cutF(gene name)|psi-mi:cutF(display_short)|uniprotkb:nlpE(gene name synonym)|uniprotkb:YPO1067(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873575|imex:IM-13779-8059	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001007795.1|refseq:NP_006081.1|ensembl:ENSG00000134255.16(gene)|ensembl:ENST00000357172.9(transcript)|ensembl:ENST00000545121.5(transcript)|go:""GO:0004142""(diacylglycerol cholinephosphotransferase activity)|go:""GO:0004307""(ethanolaminephosphotransferase activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006646""(phosphatidylethanolamine biosynthetic process)|go:""GO:0006656""(phosphatidylcholine biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0047359""(1-alkenyl-2-acylglycerol choline phosphotransferase activity)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|interpro:IPR048254|mint:Q9Y6K0|rcsb pdb:8GYW|rcsb pdb:8GYX|reactome:R-HSA-1483191|reactome:R-HSA-1483213|refseq:NP_001317672.1|panther:PTHR10414(orthology-group)"	interpro:IPR007298(Copper resistance lipoprotein NlpE)|interpro:IPR033450|interpro:IPR038139|interpro:IPR043176|refseq:YP_002346111.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M5xOOr596HTYFySYQ0c2LgyK5Pc9606	rogid:ryLPtdXQoNwxiqxUzYaySoAkJkc632	intact-crc:065BD903B5C20043|rigid:6f9Q0Pi12RuS5yu6vIOXNWFiNz0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PFC1	uniprotkb:Q9HC77	intact:EBI-2873589|uniprotkb:Q74Q87|uniprotkb:A0A5P8YDA8|uniprotkb:Q7CGT0|uniprotkb:A0A0H2W9G7	intact:EBI-946194|uniprotkb:Q2KHM6|uniprotkb:Q5T6R5|uniprotkb:Q96KS5|uniprotkb:Q9C067|uniprotkb:Q5JPD5|ensembl:ENSP00000371308.4	psi-mi:a0a2s9pfc1_yerpe(display_long)|uniprotkb:ubiH(gene name)|psi-mi:ubiH(display_short)|uniprotkb:YPO0909(locus name)	psi-mi:cpap_human(display_long)|uniprotkb:CPAP(gene name)|psi-mi:CPAP(display_short)|uniprotkb:CENPJ(gene name synonym)|uniprotkb:Centromere protein J(gene name synonym)|uniprotkb:Centrosome assembly and centriole elongation protein(gene name synonym)|uniprotkb:LAG-3-associated protein(gene name synonym)|uniprotkb:LAP(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:LYST-interacting protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873594|imex:IM-13779-8058	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010971(Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6)|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR011295(2-polyprenyl-6-methoxyphenol 4-hydroxylase)|interpro:IPR018168|refseq:WP_002209951.1|interpro:IPR036188|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0008681""(2-octaprenyl-6-methoxyphenol hydroxylase activity)|go:""GO:0071949""(FAD binding)|interpro:IPR051205|refseq:YP_002345957.1"	"ensembl:ENSG00000151849.16(gene)|ensembl:ENST00000381884.9(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007099""(centriole replication)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0008275""(gamma-tubulin small complex)|go:""GO:0015631""(tubulin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030954""(astral microtubule nucleation)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0044458""(motile cilium assembly)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0046601""(positive regulation of centriole replication)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0051301""(cell division)|go:""GO:0060236""(regulation of mitotic spindle organization)|go:""GO:0060271""(cilium assembly)|go:""GO:0061511""(centriole elongation)|go:""GO:0120099""(procentriole replication complex)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|go:""GO:1902857""(positive regulation of non-motile cilium assembly)|go:""GO:1903724""(positive regulation of centriole elongation)|go:""GO:1904951""(positive regulation of establishment of protein localization)|go:""GO:1905515""(non-motile cilium assembly)|go:""GO:1905832""(positive regulation of spindle assembly)|interpro:IPR009852(T-complex 10/CenJ, C-terminal)|interpro:IPR026581|interpro:IPR047002|mint:Q9HC77|rcsb pdb:5EIB|rcsb pdb:5ITZ|rcsb pdb:7Q1E|rcsb pdb:7Q1F|rcsb pdb:7Z0F|rcsb pdb:7Z0G|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6804115|reactome:R-HSA-8854518|refseq:NP_060921.3|dip:DIP-49904N|efo:""Orphanet:2512""|efo:""Orphanet:808""|panther:PTHR10331(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XWjXLnZHuGLVKcJ462Yke2V5Mpo632	rogid:y2LeLFP5R4hOjDjIkXsY1bZE3IA9606	intact-crc:7C9F7785762030E0|rigid:F561FejBpQZedKVjNR/tMr7Livk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96MT8	uniprotkb:A0A5P8YGL4	intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129.1|ensembl:ENSP00000475903.1|ensembl:ENSP00000502085.1|ensembl:ENSP00000506896.1	intact:EBI-2842269	psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:a0a5p8ygl4_yerpe(display_long)|uniprotkb:y2085(locus name)|uniprotkb:rnfC(gene name)|psi-mi:rnfC(display_short)|uniprotkb:Rnf electron transport complex subunit C(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873582|imex:IM-13779-8057	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2512""|dip:DIP-36374N|ensembl:ENSG00000182923.20(gene)|ensembl:ENST00000513612.7(transcript)|ensembl:ENST00000606977.5(transcript)|ensembl:ENST00000675561.1(transcript)|ensembl:ENST00000683596.1(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000922""(spindle pole)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0007099""(centriole replication)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050821""(protein stabilization)|go:""GO:0051225""(spindle assembly)|go:""GO:0051301""(cell division)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0098535""(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:""GO:1900045""(negative regulation of protein K63-linked ubiquitination)|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|rcsb pdb:7W91|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_011511496.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|panther:PTHR18875(orthology-group)"	"interpro:IPR010208(Electron transport complex, RnfC)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR017896|interpro:IPR017900|interpro:IPR019554|interpro:IPR026902|interpro:IPR037225|refseq:WP_002223606.1|uniprotkb:Q8D0I9(uniprot-removed-ac)|go:""GO:0005886""(plasma membrane)|go:""GO:0009055""(electron transfer activity)|go:""GO:0022900""(electron transport chain)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606	rogid:NRqQl9HrLq9sWIRyxpxhQ0JPxQo632	intact-crc:8B2C5F4F2EAF11D8|rigid:j9OZ5bcXf9Duohg8dFv8zfjxHwY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00450	uniprotkb:Q8CL89	intact:EBI-1220171|uniprotkb:Q14063|uniprotkb:Q2PP18|uniprotkb:Q9UKS4|ensembl:ENSP00000264613.6	intact:EBI-2839866	psi-mi:ceru_human(display_long)|uniprotkb:CP(gene name)|psi-mi:CP(display_short)|uniprotkb:Glutathione peroxidase ceruloplasmin(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin ceruloplasmin(gene name synonym)|uniprotkb:Cuproxidase ceruloplasmin(gene name synonym)|uniprotkb:Ferroxidase ceruloplasmin(gene name synonym)	psi-mi:q8cl89_yerpe(display_long)|uniprotkb:y1833(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873568|imex:IM-13779-8056	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:48818""|ensembl:ENSG00000047457.14(gene)|ensembl:ENST00000264613.11(transcript)|go:""GO:0004322""(ferroxidase activity)|go:""GO:0004602""(glutathione peroxidase activity)|go:""GO:0005507""(copper ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006826""(iron ion transport)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016724""(oxidoreductase activity, acting on metal ions, oxygen as acceptor)|go:""GO:0047066""(phospholipid-hydroperoxide glutathione peroxidase activity)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR002355(Multicopper oxidase, copper-binding site)|interpro:IPR008972(Cupredoxin)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR033138|interpro:IPR045087|interpro:IPR048236|mint:P00450|rcsb pdb:1KCW|rcsb pdb:2J5W|rcsb pdb:4EJX|rcsb pdb:4ENZ|reactome:R-HSA-381426|reactome:R-HSA-425410|reactome:R-HSA-5619049|reactome:R-HSA-5619060|reactome:R-HSA-8957275|reactome:R-HSA-917937|refseq:NP_000087.1|panther:PTHR11709(orthology-group)"	interpro:IPR051551	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WRZie4U5i0WA/bStRjFBvYK8F009606	rogid:kFqNelFqfI7J+vafdsofmQ0p0zA632	intact-crc:F858084D3C7FBA6D|rigid:6patwW1/YJLTEoRavDOtH7YXYvk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43303	uniprotkb:A0A0H2W2N9	intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803.5	intact:EBI-2840467|uniprotkb:Q74XT4|uniprotkb:Q0WBR4|uniprotkb:A0A384L498|uniprotkb:Q7CKD3|uniprotkb:A0A3N4B9W7	psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym)	psi-mi:a0a0h2w2n9_yerpe(display_long)|uniprotkb:degP(gene name)|psi-mi:degP(display_short)|uniprotkb:gsrA(gene name synonym)|uniprotkb:htrA(gene name synonym)|uniprotkb:ptd(gene name synonym)|uniprotkb:YPO3382(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873625|imex:IM-13779-8064	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001310498.1|panther:PTHR13594(orthology-group)|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540.17(gene)|ensembl:ENST00000381396.9(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0007099""(centriole replication)|go:""GO:0032053""(ciliary basal body organization)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045724""(positive regulation of cilium assembly)|go:""GO:0051298""(centrosome duplication)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424"	"interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:WP_002209370.1|refseq:YP_002348274.1|interpro:IPR036034"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Gvda4RoDRcY+G50iRW5T+haubps9606	rogid:wh5TqHAdstARdvvFDyS2kqzSnxY632	intact-crc:D8395DC914CC5C7B|rigid:tUYULqMM1rrCfs4mVTvuZpmEmW4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15027	uniprotkb:Q8ZA76	intact:EBI-751746|uniprotkb:Q53XN9|ensembl:ENSP00000158762.3|ensembl:ENSP00000499859.1	intact:EBI-2846943|uniprotkb:Q0WA76	psi-mi:acap1_human(display_long)|uniprotkb:ACAP1(gene name)|psi-mi:ACAP1(display_short)|uniprotkb:Centaurin-beta-1(gene name synonym)|uniprotkb:CENTB1(gene name synonym)|uniprotkb:KIAA0050(gene name synonym)	psi-mi:glgx_yerpe(display_long)|uniprotkb:glgX(gene name)|psi-mi:glgX(display_short)|uniprotkb:Limit dextrin alpha-1,6-maltotetraose-hydrolase(gene name synonym)|uniprotkb:YPO3941(locus name)|uniprotkb:YP_3303(locus name)|uniprotkb:y3887(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873618|imex:IM-13779-8063	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055531.1|ensembl:ENSG00000072818.12(gene)|ensembl:ENSG00000288169.1(gene)|ensembl:ENST00000158762.8(transcript)|ensembl:ENST00000672212.1(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0055038""(recycling endosome membrane)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR004148(BAR)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|interpro:IPR045258|mint:Q15027|rcsb pdb:3JUE|rcsb pdb:3T9K|rcsb pdb:4CKG|rcsb pdb:4CKH|rcsb pdb:4F1P|rcsb pdb:4NSW|rcsb pdb:5H3D|panther:PTHR23180(orthology-group)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR022844|interpro:IPR011837(Glycogen debranching enzyme GlgX)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR040784|go:""GO:0004133""(obsolete glycogen debranching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005980""(glycogen catabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_002209499.1|interpro:IPR044505|refseq:YP_002348812.1|panther:PTHR43002(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pdHptA2uWwLfGAtHieVj+hm1udw9606	rogid:8sHtj0obGqvrIdGE1JWk8okcbRM632	intact-crc:32542E0CCA56227C|rigid:TVA3b1REBBGe9oTF5sDv/Nddqhs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q00532	uniprotkb:A0A3N4B652	intact:EBI-2873635|ensembl:ENSP00000379176.2|uniprotkb:Q2M3A4|uniprotkb:Q6QUA0|uniprotkb:Q8WXQ5|uniprotkb:J3KMW1	intact:EBI-2841456|uniprotkb:Q74UD2|uniprotkb:A0A0H2W5A2|uniprotkb:Q7CIY7	psi-mi:cdkl1_human(display_long)|uniprotkb:CDKL1(gene name)|psi-mi:CDKL1(display_short)|uniprotkb:Protein kinase p42 KKIALRE(gene name synonym)|uniprotkb:Serine/threonine-protein kinase KKIALRE(gene name synonym)	psi-mi:a0a3n4b652_yerpe(display_long)|uniprotkb:cheA(gene name)|psi-mi:cheA(display_short)|uniprotkb:YPO1666(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873632|imex:IM-13779-8062	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100490.10(gene)|ensembl:ENST00000395834.6(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004693""(cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0035869""(ciliary transition zone)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1902017""(regulation of cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050108|mint:Q00532|rcsb pdb:4AGU|refseq:NP_004187.2|refseq:XP_005268214.1|refseq:XP_016877218.1|panther:PTHR24056(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR002545(CheW-like protein)|interpro:IPR015162(CheY binding)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR008207(""Signal transduction histidine kinase, phosphotransfer (Hpt) region"")|interpro:IPR004105(Signal transduction histidine kinase, subgroup, homodimeric)|interpro:IPR005467(Signal transduction histidine kinase, core)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006935""(chemotaxis)|refseq:YP_002346673.1|interpro:IPR035891|interpro:IPR036061|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037006|interpro:IPR051315|panther:PTHR43395(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CbmSJfDHQVK6FOPcrVaOGJl4BXo9606	rogid:KztfI7bmNuR6U1Zo6bOZct0DtBc632	intact-crc:4DED942E36E7364C|rigid:sHx2I8nE9fhRgjpIfAQENztS1c8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WZ64	uniprotkb:Q8ZAS8	intact:EBI-2836524|uniprotkb:Q9Y4E4|uniprotkb:Q96L70|uniprotkb:Q7Z2L5|uniprotkb:Q4W5D2|ensembl:ENSP00000302895.4|intact:EBI-2873601|uniprotkb:Q96P49	intact:EBI-2858695|uniprotkb:Q0WAU5|uniprotkb:Q74RG2|uniprotkb:Q7CLD6	psi-mi:arap2_human(display_long)|uniprotkb:ARAP2(gene name)|psi-mi:ARAP2(display_short)|uniprotkb:CENTD1(gene name synonym)|uniprotkb:KIAA0580(gene name synonym)|uniprotkb:Centaurin-delta-1(gene name synonym)|uniprotkb:Protein PARX(gene name synonym)	psi-mi:malk_yerpe(display_long)|uniprotkb:malK(gene name)|psi-mi:malK(display_short)|uniprotkb:YPO3712(locus name)|uniprotkb:y0031(locus name)|uniprotkb:YP_3074(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873611|imex:IM-13779-8061	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000047365.13(gene)|ensembl:ENST00000303965.9(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0007165""(signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0046872""(metal ion binding)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037278|interpro:IPR037858|interpro:IPR038508|interpro:IPR052227|mint:Q8WZ64|rcsb pdb:1X40|rcsb pdb:2COD|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|refseq:NP_056045.2|refseq:XP_016863188.1|panther:PTHR45899(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR015855(ABC transporter, maltose/maltodextrin import, MalK)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR027417|interpro:IPR040582|refseq:WP_002212091.1|go:""GO:0005524""(ATP binding)|go:""GO:0015423""(ABC-type maltose transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055052""(""ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing"")|go:""GO:1990060""(maltose transport complex)|interpro:IPR047641|refseq:YP_002348593.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR43875(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YFYTjlg562/jgD4JtXsh0N6Pkxg9606	rogid:iYvtpY6Sey6L+FCWA7ApyIW7S6Q632	intact-crc:E21AA4067FB4DCB9|rigid:Fb3jNTolrsoYsPwGG5cYcDogu8k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GX14	uniprotkb:Q16543	intact:EBI-2844750|uniprotkb:Q74SI1|uniprotkb:Q0WCR6|uniprotkb:Q7CJG1|uniprotkb:A0A5P8YHZ2|uniprotkb:A0A384L3F5	intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005.1|intact:EBI-21355356	psi-mi:a0a2u2gx14_yerpe(display_long)|uniprotkb:YPO2998(locus name)	psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873673|imex:IM-13779-8069	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039420|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|refseq:WP_002208494.1|interpro:IPR036388|refseq:YP_002347922.1"	"refseq:NP_008996.1|ensembl:ENSG00000105401.10(gene)|ensembl:ENST00000222005.7(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006605""(protein targeting)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0060334""(regulation of type II interferon-mediated signaling pathway)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1990565""(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|rcsb pdb:7Z37|rcsb pdb:7Z38|rcsb pdb:7ZR0|rcsb pdb:7ZR5|rcsb pdb:7ZR6|rcsb pdb:8GAE|rcsb pdb:8GFT|rcsb pdb:8U1L|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|dip:DIP-27560N|panther:PTHR12800(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:l1lO/0GX67is8Bzo8qlutJlO8c4632	rogid:iajhitd2iEmd17KfpU/nMaKc4049606	intact-crc:76378291A5C51815|rigid:GyWeo+QKiZdInReUsTU5tkxIqwU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D194	uniprotkb:Q16543	intact:EBI-2847851|uniprotkb:Q74XR4	intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005.1|intact:EBI-21355356	psi-mi:q8d194_yerpe(display_long)|uniprotkb:dAK1_1(gene name)|psi-mi:dAK1_1(display_short)|uniprotkb:YP_0337(locus name)|uniprotkb:y0840(locus name)	psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873666|imex:IM-13779-8067	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004006(Dak kinase)|go:""GO:0004371""(glycerone kinase activity)|go:""GO:0006071""(glycerol metabolic process)|interpro:IPR050861"	"refseq:NP_008996.1|ensembl:ENSG00000105401.10(gene)|ensembl:ENST00000222005.7(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006605""(protein targeting)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0060334""(regulation of type II interferon-mediated signaling pathway)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1990565""(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|rcsb pdb:7Z37|rcsb pdb:7Z38|rcsb pdb:7ZR0|rcsb pdb:7ZR5|rcsb pdb:7ZR6|rcsb pdb:8GAE|rcsb pdb:8GFT|rcsb pdb:8U1L|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|dip:DIP-27560N|panther:PTHR12800(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:PGSwAYXIFUUnJmzpLaHT1vlvQxc632	rogid:iajhitd2iEmd17KfpU/nMaKc4049606	intact-crc:7FF178275E08C506|rigid:drq1RqJJFhSlyomP6wfJLJ2Y0Ys	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50613	uniprotkb:A0A380PKN3	intact:EBI-1245958|uniprotkb:Q9BS60|uniprotkb:Q9UE19|ensembl:ENSP00000256443.3|ensembl:ENSP00000479116.1	intact:EBI-2845132|uniprotkb:Q74W20|uniprotkb:Q7CJU3|uniprotkb:A0A0H2W2U3	psi-mi:cdk7_human(display_long)|uniprotkb:CDK7(gene name)|psi-mi:CDK7(display_short)|uniprotkb:MO15(gene name synonym)|uniprotkb:CAK(gene name synonym)|uniprotkb:CAK1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex kinase subunit(gene name synonym)|uniprotkb:39 kDa protein kinase(gene name synonym)|uniprotkb:CDKN7(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:Cell division protein kinase 7(gene name synonym)|uniprotkb:CDK-activating kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 1(gene name synonym)	psi-mi:a0a380pkn3_yerpe(display_long)|uniprotkb:nagA(gene name)|psi-mi:nagA(display_short)|uniprotkb:YPO2626(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873645|imex:IM-13779-8065	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001790.1|ensembl:ENSG00000134058.12(gene)|ensembl:ENSG00000277273.5(gene)|ensembl:ENST00000256443.8(transcript)|ensembl:ENST00000615305.4(transcript)|go:""GO:0000307""(cyclin-dependent protein kinase holoenzyme complex)|go:""GO:0000439""(transcription factor TFIIH core complex)|go:""GO:0001650""(fibrillar center)|go:""GO:0001673""(male germ cell nucleus)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004693""(cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005675""(transcription factor TFIIH holo complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006367""(transcription initiation at RNA polymerase II promoter)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0008353""(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:""GO:0042795""(snRNA transcription by RNA polymerase II)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051301""(cell division)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070516""(CAK-ERCC2 complex)|go:""GO:0070985""(transcription factor TFIIK complex)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140833""(RNA polymerase II CTD heptapeptide repeat Y1 kinase activity)|go:""GO:0140834""(RNA polymerase II CTD heptapeptide repeat S2 kinase activity)|go:""GO:0140835""(RNA polymerase II CTD heptapeptide repeat T4 kinase activity)|go:""GO:0140836""(RNA polymerase II CTD heptapeptide repeat S5 kinase activity)|go:""GO:0140837""(RNA polymerase II CTD heptapeptide repeat S7 kinase activity)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037770|interpro:IPR050108|mint:P50613|rcsb pdb:1UA2|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8BVW|rcsb pdb:8BYQ|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8ORM|rcsb pdb:8P4Z|rcsb pdb:8P6V|rcsb pdb:8P6W|rcsb pdb:8P6X|rcsb pdb:8P6Y|rcsb pdb:8P6Z|rcsb pdb:8P70|rcsb pdb:8P71|rcsb pdb:8P72|rcsb pdb:8P73|rcsb pdb:8P74|rcsb pdb:8P75|rcsb pdb:8P76|rcsb pdb:8P77|rcsb pdb:8P78|rcsb pdb:8P79|rcsb pdb:8P7L|rcsb pdb:8PLZ|rcsb pdb:8PYR|rcsb pdb:8R99|rcsb pdb:8R9A|rcsb pdb:8R9B|rcsb pdb:8R9O|rcsb pdb:8R9S|rcsb pdb:8R9U|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|refseq:NP_001310998.1|refseq:NP_001310999.1|refseq:NP_001311000.1|refseq:NP_001311006.1|dip:DIP-5995N|panther:PTHR24056(orthology-group)"	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR003764(N-acetylglucosamine-6-phosphate deacetylase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|go:""GO:0006046""(N-acetylglucosamine catabolic process)|go:""GO:0008448""(N-acetylglucosamine-6-phosphate deacetylase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002210351.1|interpro:IPR032466|refseq:YP_002347582.1|panther:PTHR11113(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:pA9dLwvlBxPUAXW3bgv5M00qezk9606	rogid:q6NCKQyXjUNP3tkI1GBvg//aflg632	intact-crc:C152366C1F8394AE|rigid:/uPsc2NdFp1KZGmynR9qWWScuBg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P60953	uniprotkb:Q8CKN6	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|uniprotkb:Q9UDI2	intact:EBI-2855015|uniprotkb:Q74S26	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:q8ckn6_yerpe(display_long)|uniprotkb:YP_2833(locus name)|uniprotkb:y3210(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873659|imex:IM-13779-8066	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:487796""|efo:""Orphanet:619363""|ensembl:ENSG00000070831.18(gene)|ensembl:ENST00000344548.8(transcript)|ensembl:ENST00000400259.5(transcript)|ensembl:ENST00000411827.2(transcript)|ensembl:ENST00000656825.1(transcript)|ensembl:ENST00000662562.2(transcript)|ensembl:ENST00000695796.1(transcript)|ensembl:ENST00000695797.1(transcript)|ensembl:ENST00000695798.1(transcript)|ensembl:ENST00000695799.1(transcript)|ensembl:ENST00000695800.1(transcript)|ensembl:ENST00000695802.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000322""(storage vacuole)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0003161""(cardiac conduction system development)|go:""GO:0003253""(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006897""(endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0007097""(nuclear migration)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008104""(protein localization)|go:""GO:0010591""(regulation of lamellipodium assembly)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0017119""(Golgi transport complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030141""(secretory granule)|go:""GO:0030175""(filopodium)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030496""(midbody)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031256""(leading edge membrane)|go:""GO:0031274""(positive regulation of pseudopodium assembly)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031435""(mitogen-activated protein kinase kinase kinase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032427""(GBD domain binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0032488""(Cdc42 protein signal transduction)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034191""(apolipoprotein A-I receptor binding)|go:""GO:0034329""(cell junction assembly)|go:""GO:0034332""(adherens junction organization)|go:""GO:0035050""(embryonic heart tube development)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048664""(neuron fate determination)|go:""GO:0051233""(spindle midzone)|go:""GO:0051489""(regulation of filopodium assembly)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0051835""(positive regulation of synapse structural plasticity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0060047""(heart contraction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060501""(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060661""(submandibular salivary gland formation)|go:""GO:0060997""(dendritic spine morphogenesis)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072384""(organelle transport along microtubule)|go:""GO:0072686""(mitotic spindle)|go:""GO:0086101""(endothelin receptor signaling pathway involved in heart process)|go:""GO:0090135""(actin filament branching)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099159""(regulation of modification of postsynaptic structure)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|rcsb pdb:1AN0|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|rcsb pdb:1A4R|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|rcsb pdb:7S0Y|rcsb pdb:8I5F|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983231|refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|panther:PTHR24072(orthology-group)|dip:DIP-31097N|ensembl:ENSP00000512180.1|ensembl:ENSP00000512182.1|ensembl:ENST00000695857.1|ensembl:ENSP00000512222.1|ensembl:ENST00000695860.1|ensembl:ENSP00000512225.1|ensembl:ENST00000315554.15|ensembl:ENSP00000314458.8|ensembl:ENSP00000341072.3|ensembl:ENSP00000383118.1|ensembl:ENSP00000398327.2|ensembl:ENSP00000499457.1|ensembl:ENSP00000499612.1|ensembl:ENSP00000512176.1|ensembl:ENSP00000512177.1|ensembl:ENSP00000512178.1|ensembl:ENSP00000512179.1"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|go:""GO:0019867""(outer membrane)|interpro:IPR036709"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/07	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rogid:1PmyGpcWP3bPwcEODrFtqgYq+a0632	intact-crc:044E7F0592395C9C|rigid:nxrVOiyJ4BzVCB23Sqy68NGpXT4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PJK8	uniprotkb:Q6P1J9	intact:EBI-2842311|uniprotkb:Q0WI69|uniprotkb:Q7CGQ2	intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405.4	psi-mi:a0a380pjk8_yerpe(display_long)|uniprotkb:clpB3(gene name)|psi-mi:clpB3(display_short)|uniprotkb:YPO0971(locus name)	psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873652|imex:IM-13779-8068	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR017729(Type VI secretion system ATPase, ClpV1)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR041546|interpro:IPR004176(Clp, N-terminal)|interpro:IPR018368|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034605""(cellular response to heat)|refseq:WP_002210013.1|interpro:IPR036628|refseq:YP_002346019.1|interpro:IPR050130|panther:PTHR11638(orthology-group)"	"ensembl:ENSG00000134371.15(gene)|ensembl:ENST00000367435.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001711""(endodermal cell fate commitment)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016593""(Cdc73/Paf1 complex)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0031442""(positive regulation of mRNA 3'-end processing)|go:""GO:0031648""(protein destabilization)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045638""(negative regulation of myeloid cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:1902808""(positive regulation of cell cycle G1/S phase transition)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|rcsb pdb:7OOP|rcsb pdb:7OPC|rcsb pdb:7OPD|rcsb pdb:7UNC|rcsb pdb:7UND|rcsb pdb:8A3Y|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_078805.3|dip:DIP-37884N|efo:""Orphanet:99880""|efo:""Orphanet:143""|efo:""Orphanet:99879""|ensembl:ENSP00000356405.4|panther:PTHR12466(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:zRQmsquHSeoveoOQnnSmxw1Hb2s632	rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606	intact-crc:FF51BBF7054DF2C7|rigid:IrXD1ulDBflfkvFHDXycGDX96/M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16543	uniprotkb:A0A3N4B418	intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005.1|intact:EBI-21355356	intact:EBI-2840046|uniprotkb:Q0WFD2|uniprotkb:Q74U73|uniprotkb:Q7CIA4|uniprotkb:A0A380PD11	psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym)	psi-mi:a0a3n4b418_yerpe(display_long)|uniprotkb:YPO2020(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873680|imex:IM-13779-8074	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_008996.1|ensembl:ENSG00000105401.10(gene)|ensembl:ENST00000222005.7(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006605""(protein targeting)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0060334""(regulation of type II interferon-mediated signaling pathway)|go:""GO:0060338""(regulation of type I interferon-mediated signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1990565""(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|rcsb pdb:7Z37|rcsb pdb:7Z38|rcsb pdb:7ZR0|rcsb pdb:7ZR5|rcsb pdb:7ZR6|rcsb pdb:8GAE|rcsb pdb:8GFT|rcsb pdb:8U1L|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|dip:DIP-27560N|panther:PTHR12800(orthology-group)"	refseq:YP_002347006.1|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032698|refseq:WP_002211233.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:iajhitd2iEmd17KfpU/nMaKc4049606	rogid:wzxT1bjS3dgwqWVrMmCge2eTVT0632	intact-crc:2F4E5E8F90643C69|rigid:C3mYhz9d8Bi93SvGd2yx3YmpadU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13042	uniprotkb:Q8CWI1	intact:EBI-994830|uniprotkb:Q96AE6|uniprotkb:Q9Y564|uniprotkb:A2A365|uniprotkb:Q5T8C8|uniprotkb:Q7Z651|ensembl:ENSP00000348554.3|ensembl:ENSP00000353549.3	intact:EBI-2845294	psi-mi:cdc16_human(display_long)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short)	psi-mi:q8cwi1_yerpe(display_long)|uniprotkb:glpC(gene name)|psi-mi:glpC(display_short)|uniprotkb:y0406(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873694|imex:IM-13779-8073	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001072113.1|refseq:NP_003894.3|refseq:NP_001305446.1|refseq:NP_001305447.1|refseq:NP_001317030.1|refseq:NP_001317033.1|refseq:NP_001317034.1|refseq:XP_016876322.1|dip:DIP-36423N|ensembl:ENSG00000130177.16(gene)|ensembl:ENST00000356221.8(transcript)|ensembl:ENST00000360383.7(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005680""(anaphase-promoting complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031145""(anaphase-promoting complex-dependent catabolic process)|go:""GO:0045842""(positive regulation of mitotic metaphase/anaphase transition)|go:""GO:0051301""(cell division)|go:""GO:0051445""(regulation of meiotic cell cycle)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0072686""(mitotic spindle)|go:""GO:0141198""(protein branched polyubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q13042|rcsb pdb:3HYM|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|rcsb pdb:8PKP|rcsb pdb:8TAR|rcsb pdb:8TAU|rcsb pdb:9GAW|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|panther:PTHR12558(orthology-group)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR004017(Cysteine-rich region, CCG)|interpro:IPR017753(Anaerobic glycerol-3-phosphate dehydrogenase, C subunit)|interpro:IPR009051(Alpha-helical ferredoxin)|go:""GO:0009061""(anaerobic respiration)|go:""GO:0009331""(""glycerol-3-phosphate dehydrogenase (FAD) complex"")|go:""GO:0016020""(membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606	rogid:Ni4uunc/ZlYLbmbLclTTzn5OT10632	intact-crc:D6D790873B3B9C9B|rigid:E1ZkvaaDNpsdu4GPyn2jpj9GAKA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01732	uniprotkb:A0A7Y8RCW6	intact:EBI-2873704|uniprotkb:Q13970|uniprotkb:B4DT80|uniprotkb:Q4ZG17|uniprotkb:D6W5M8|ensembl:ENSP00000283635.3|ensembl:ENSP00000386559.2	intact:EBI-2845056|uniprotkb:Q7CKM5|uniprotkb:A0A5P8YBL8|uniprotkb:Q0WJU7	psi-mi:cd8a_human(display_long)|uniprotkb:CD8A(gene name)|psi-mi:CD8A(display_short)|uniprotkb:MAL(gene name synonym)|uniprotkb:T-lymphocyte differentiation antigen T8/Leu-2(gene name synonym)	psi-mi:a0a7y8rcw6_yerpe(display_long)|uniprotkb:YPO0363(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873713|imex:IM-13779-8072	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000153563.17(gene)|ensembl:ENST00000283635.8(transcript)|ensembl:ENST00000409511.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0015026""(coreceptor activity)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0023024""(MHC class I protein complex binding)|go:""GO:0042101""(T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045065""(cytotoxic T cell differentiation)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015468(CD8 alpha chain)|interpro:IPR036179|rcsb pdb:1AKJ|rcsb pdb:1CD8|rcsb pdb:1Q69|rcsb pdb:2HP4|rcsb pdb:3QZW|rcsb pdb:7UMG|rcsb pdb:7UVF|rcsb pdb:8EW6|reactome:R-HSA-198933|refseq:NP_001139345.1|refseq:NP_001759.3|refseq:NP_741969.1|efo:""Orphanet:169085""|panther:PTHR10441(orthology-group)"	"interpro:IPR024393|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR011066(Mechanosensitive ion channel MscS, C-terminal)|interpro:IPR006685(Mechanosensitive ion channel MscS)|interpro:IPR011014(Mechanosensitive ion channel MscS, transmembrane-2)|interpro:IPR006686(Mechanosensitive ion channel MscS, conserved site)|interpro:IPR025692|go:""GO:0005886""(plasma membrane)|go:""GO:0008381""(mechanosensitive monoatomic ion channel activity)|interpro:IPR049142|interpro:IPR049278|interpro:IPR023408|refseq:YP_002345441.1|interpro:IPR052702"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:P1dPeA7yUx0TUno/Poaas9TU6gk9606	rogid:z6l0v0GxSQqbhV/esC/hffWqLG8632	intact-crc:B1EDCC005AEB8415|rigid:9Uol44iud+xI/ubkiy3HSKaRxXU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01732	uniprotkb:Q8ZDJ2	intact:EBI-2873704|uniprotkb:Q13970|uniprotkb:B4DT80|uniprotkb:Q4ZG17|uniprotkb:D6W5M8|ensembl:ENSP00000283635.3|ensembl:ENSP00000386559.2	intact:EBI-2844031|uniprotkb:Q0WDV6	psi-mi:cd8a_human(display_long)|uniprotkb:CD8A(gene name)|psi-mi:CD8A(display_short)|uniprotkb:MAL(gene name synonym)|uniprotkb:T-lymphocyte differentiation antigen T8/Leu-2(gene name synonym)	psi-mi:a2mgh_yerpe(display_long)|uniprotkb:YPO2573(locus name)|uniprotkb:y1143(locus name)|uniprotkb:YP_1141(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873701|imex:IM-13779-8071	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000153563.17(gene)|ensembl:ENST00000283635.8(transcript)|ensembl:ENST00000409511.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0015026""(coreceptor activity)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0023024""(MHC class I protein complex binding)|go:""GO:0042101""(T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045065""(cytotoxic T cell differentiation)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015468(CD8 alpha chain)|interpro:IPR036179|rcsb pdb:1AKJ|rcsb pdb:1CD8|rcsb pdb:1Q69|rcsb pdb:2HP4|rcsb pdb:3QZW|rcsb pdb:7UMG|rcsb pdb:7UVF|rcsb pdb:8EW6|reactome:R-HSA-198933|refseq:NP_001139345.1|refseq:NP_001759.3|refseq:NP_741969.1|efo:""Orphanet:169085""|panther:PTHR10441(orthology-group)"	"interpro:IPR021868|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|go:""GO:0004866""(endopeptidase inhibitor activity)|interpro:IPR041203|interpro:IPR041246|interpro:IPR041462|refseq:YP_002347532.1|interpro:IPR051802|panther:PTHR40094(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:P1dPeA7yUx0TUno/Poaas9TU6gk9606	rogid:9FN1refl1me6jgo6ehCPO8MzV8Y632	intact-crc:B768083F4B4A537A|rigid:3kU++tW5zrWU5sURRRvbLZ9jKkY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UJX2	uniprotkb:Q8CZM4	intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350.2	intact:EBI-2872933|uniprotkb:Q74YC4	psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym)	"psi-mi:q8czm4_yerpe(display_long)|uniprotkb:glnL(gene name)|psi-mi:glnL(display_short)|uniprotkb:ntrB(gene name synonym)|uniprotkb:YP_0024(locus name)|uniprotkb:y3805(locus name)|uniprotkb:""Nitrogen regulation protein NR(II)""(gene name synonym)|uniprotkb:Nitrogen regulator II(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873687|imex:IM-13779-8070	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004652.2|ensembl:ENSG00000094880.11(gene)|ensembl:ENST00000394886.7(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005680""(anaphase-promoting complex)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0007091""(metaphase/anaphase transition of mitotic cell cycle)|go:""GO:0007096""(regulation of exit from mitosis)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0031145""(anaphase-promoting complex-dependent catabolic process)|go:""GO:0045842""(positive regulation of mitotic metaphase/anaphase transition)|go:""GO:0051301""(cell division)|go:""GO:0051445""(regulation of meiotic cell cycle)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:0141198""(protein branched polyubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|rcsb pdb:8PKP|rcsb pdb:8TAR|rcsb pdb:8TAU|rcsb pdb:9GAW|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-68867|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|dip:DIP-32959N|panther:PTHR12558(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0009399""(nitrogen fixation)|go:""GO:0016787""(hydrolase activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rogid:Bd2hsoaxNqpjurEBsRlC2uKozD0632	intact-crc:88B6500E4F26A299|rigid:Y+qrcgVBABvr+tfG2m0z7v/Zbck	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40259	uniprotkb:Q8CKF8	intact:EBI-2873732|uniprotkb:Q9BU06|uniprotkb:Q53FS2|ensembl:ENSP00000006750.4	intact:EBI-2844579|uniprotkb:Q74RR5	psi-mi:cd79b_human(display_long)|uniprotkb:CD79B(gene name)|psi-mi:CD79B(display_short)|uniprotkb:B29(gene name synonym)|uniprotkb:IGB(gene name synonym)|uniprotkb:B-cell-specific glycoprotein B29(gene name synonym)|uniprotkb:Ig-beta(gene name synonym)|uniprotkb:Immunoglobulin-associated B29 protein(gene name synonym)	psi-mi:q8ckf8_yerpe(display_long)|uniprotkb:y3542(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873738|imex:IM-13779-8078	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-59497N|ensembl:ENSG00000007312.14(gene)|ensembl:ENST00000006750.8(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0019815""(B cell receptor complex)|go:""GO:0030183""(B cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071755""(IgM B cell receptor complex)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3KG5|rcsb pdb:7WSO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|refseq:NP_000617.1|refseq:NP_001035022.1|refseq:NP_067613.1|efo:""Orphanet:33110""|panther:PTHR14334(orthology-group)|ensembl:ENSP00000006750.4|ensembl:ENST00000349817.2|ensembl:ENSP00000245862.2|ensembl:ENST00000392795.7|ensembl:ENSP00000376544.3"	interpro:IPR037883	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:x+XeaeQ1foE+V4VXa26+WhK28O09606	rogid:bULfeL7EI8ZLrm+OLqILFkvARMg632	intact-crc:54D622BFF5F8AC7C|rigid:JyLKmvKSNAGb+HnlA1jPKLnHLnU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43866	uniprotkb:A0A2S9PM60	intact:EBI-2623436|uniprotkb:A8K7M5|uniprotkb:Q6UX63|ensembl:ENSP00000357156.4	intact:EBI-2853592|uniprotkb:Q74TV9|uniprotkb:Q0WEU8|uniprotkb:Q7CIL8|uniprotkb:A0A384KHN0	psi-mi:cd5l_human(display_long)|uniprotkb:API6(gene name synonym)|uniprotkb:CT-2(gene name synonym)|uniprotkb:IgM-associated peptide(gene name synonym)|uniprotkb:SP-alpha(gene name synonym)|uniprotkb:UNQ203/PRO229(orf name)|uniprotkb:Apoptosis inhibitor expressed by macrophages(gene name synonym)|uniprotkb:CD5L(gene name)|psi-mi:CD5L(display_short)	psi-mi:a0a2s9pm60_yerpe(display_long)|uniprotkb:supX(gene name)|psi-mi:supX(display_short)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:topA(gene name synonym)|uniprotkb:YPO2218(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873768|imex:IM-13779-8079	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005885.1|ensembl:ENSG00000073754.6(gene)|ensembl:ENST00000368174.5(transcript)|go:""GO:0002376""(immune system process)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0009986""(cell surface)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0031638""(zymogen activation)|go:""GO:0072562""(blood microparticle)|go:""GO:1903661""(positive regulation of complement-dependent cytotoxicity)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR036772|rcsb pdb:8WYR|rcsb pdb:8WYS|refseq:NP_001334627.1|panther:PTHR48071(orthology-group)"	"interpro:IPR023406|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR023405|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR005733(DNA topoisomerase I, bacterial-type)|interpro:IPR013263(DNA topoisomerase I, zinc ribbon-like, bacterial-type)|interpro:IPR006171(TOPRIM)|refseq:WP_002210622.1|interpro:IPR034149|go:""GO:0003677""(DNA binding)|go:""GO:0003917""(""DNA topoisomerase type I (single strand cut, ATP-independent) activity"")|go:""GO:0005694""(chromosome)|go:""GO:0006265""(DNA topological change)|go:""GO:0046872""(metal ion binding)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR049330|interpro:IPR028612|refseq:YP_002347190.1|panther:PTHR42785(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:g+Yen5g8QKKkkcmIVSd0eylQJYg9606	rogid:sBCN9yVi7vZQU8tykRnvKWsTra8632	intact-crc:7BA3A78A3925233E|rigid:bBrA2ob9j1P2BQDkXD6KhXY5eRg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5LAS3	uniprotkb:Q01151	intact:EBI-2858353|uniprotkb:A0A1U8QWA8|uniprotkb:Q74YJ3|uniprotkb:Q9ZGY3|uniprotkb:Q7ARA8|uniprotkb:A0A0H2W1Z2|uniprotkb:A0A384LAQ1	intact:EBI-2873723|uniprotkb:Q5THX9|ensembl:ENSP00000368450.3	psi-mi:a0a3g5las3_yerpe(display_long)|uniprotkb:YPMT1.86c(locus name)	psi-mi:cd83_human(display_long)|uniprotkb:CD83(gene name)|psi-mi:CD83(display_short)|uniprotkb:B-cell activation protein(gene name synonym)|uniprotkb:Cell surface protein HB15(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873720|imex:IM-13779-8075	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395432.1|refseq:WP_002228802.1	"refseq:NP_001035370.1|refseq:NP_004224.1|refseq:NP_001238830.1|ensembl:ENSG00000112149.11(gene)|ensembl:ENST00000379153.4(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0032713""(negative regulation of interleukin-4 production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0043367""(CD4-positive, alpha-beta T cell differentiation)|go:""GO:0043372""(positive regulation of CD4-positive, alpha-beta T cell differentiation)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:5MIX|rcsb pdb:5MJ0|rcsb pdb:5MJ1|rcsb pdb:5MJ2|panther:PTHR15193(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7tH07Yv4XPfqK+U1ZykbkUm6Uuk632	rogid:ICaEMYG0gkpGAtk5ErEZlHZRcrU9606	intact-crc:6D40D6A8019C63D0|rigid:yKZcaaASYWTWM988vmF/06eFXnQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43866	uniprotkb:A0A3G5KZU3	intact:EBI-2623436|uniprotkb:A8K7M5|uniprotkb:Q6UX63|ensembl:ENSP00000357156.4	intact:EBI-2850940	psi-mi:cd5l_human(display_long)|uniprotkb:API6(gene name synonym)|uniprotkb:CT-2(gene name synonym)|uniprotkb:IgM-associated peptide(gene name synonym)|uniprotkb:SP-alpha(gene name synonym)|uniprotkb:UNQ203/PRO229(orf name)|uniprotkb:Apoptosis inhibitor expressed by macrophages(gene name synonym)|uniprotkb:CD5L(gene name)|psi-mi:CD5L(display_short)	psi-mi:a0a3g5kzu3_yerpe(display_long)|uniprotkb:y0245(locus name)|uniprotkb:ssuA(gene name)|psi-mi:ssuA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873761|imex:IM-13779-8077	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005885.1|ensembl:ENSG00000073754.6(gene)|ensembl:ENST00000368174.5(transcript)|go:""GO:0002376""(immune system process)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006968""(cellular defense response)|go:""GO:0009986""(cell surface)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0031638""(zymogen activation)|go:""GO:0072562""(blood microparticle)|go:""GO:1903661""(positive regulation of complement-dependent cytotoxicity)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR036772|rcsb pdb:8WYR|rcsb pdb:8WYS|refseq:NP_001334627.1|panther:PTHR48071(orthology-group)"	"interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR010067(ABC transporter, substrate-binding protein, aliphatic sulphonates)|interpro:IPR015168(NMT1/THI5 like)|uniprotkb:A0A6B3T643(uniprot-removed-ac)|go:""GO:0016020""(membrane)|go:""GO:0042597""(periplasmic space)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|refseq:WP_002220949.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:g+Yen5g8QKKkkcmIVSd0eylQJYg9606	rogid:kuMqjHfkYUIBJ4hy+1j+bwqjjo4632	intact-crc:F0C0909882B71A6A|rigid:M/2WIrG7u/HJqf9TdtCeuqEYtCE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30203	uniprotkb:A0A380PDG1	intact:EBI-2873748|uniprotkb:Q8WWJ3|uniprotkb:Q8WWJ4|uniprotkb:Q8WWJ5|uniprotkb:Q8WWJ6|uniprotkb:Q8WWJ7|uniprotkb:Q9UMF2|uniprotkb:Q9Y4K8|uniprotkb:Q9Y4L0|uniprotkb:Q9Y4K7|uniprotkb:Q9Y4K9|uniprotkb:A4KAD4|uniprotkb:A4KAD5|ensembl:ENSP00000323280.7	intact:EBI-2858548|uniprotkb:Q74TV6|uniprotkb:Q7CIL5|uniprotkb:A0A0H2W529	psi-mi:cd6_human(display_long)|uniprotkb:CD6(gene name)|psi-mi:CD6(display_short)|uniprotkb:T12(gene name synonym)|uniprotkb:TP120(gene name synonym)	psi-mi:a0a380pdg1_yerpe(display_long)|uniprotkb:acn(gene name)|psi-mi:acn(display_short)|uniprotkb:acnA(gene name synonym)|uniprotkb:YPO2221(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873745|imex:IM-13779-8076	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011543664.1|refseq:NP_006716.3|refseq:XP_006718804.1|refseq:NP_001241679.1|refseq:NP_001241680.1|dip:DIP-43704N|ensembl:ENSG00000013725.14(gene)|ensembl:ENST00000313421.11(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0001772""(immunological synapse)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002438""(acute inflammatory response to antigenic stimulus)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0009986""(cell surface)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0070891""(lipoteichoic acid binding)|go:""GO:1900017""(positive regulation of cytokine production involved in inflammatory response)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR036772|mint:P30203|rcsb pdb:5A2E|panther:PTHR19331(orthology-group)"	"interpro:IPR044137|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR018136|refseq:WP_002215187.1|go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006101""(citrate metabolic process)|go:""GO:0030350""(iron-responsive element binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR036008|refseq:YP_002347193.1|panther:PTHR11670(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7GTuuSJHssuyL3S2CiBAN14eP9c9606	rogid:U+Apr4nPvMOLOKyPanMpXDngrWk632	intact-crc:2E2336D9CC450874|rigid:WEt1jy8jxBD/SsMrkwBf6+reOXs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYH3	uniprotkb:P08575	intact:EBI-2842340|uniprotkb:Q74PE3|uniprotkb:Q0W9X2|uniprotkb:Q7CFQ3|uniprotkb:A0A5P8YAI4|uniprotkb:A0A384L096	intact:EBI-1341|uniprotkb:A8K7W6|uniprotkb:Q16614|uniprotkb:Q9H0Y6|uniprotkb:A0A0A0MT22|uniprotkb:X6R433|ensembl:ENSP00000411355.3|ensembl:ENSP00000458322.2|ensembl:ENSP00000461074.2	psi-mi:a0a2u2gyh3_yerpe(display_long)|uniprotkb:fdoH(gene name)|psi-mi:fdoH(display_short)|uniprotkb:YPO4057(locus name)	psi-mi:ptprc_human(display_long)|uniprotkb:PTPRC(gene name)|psi-mi:PTPRC(display_short)|uniprotkb:CD45(gene name synonym)|uniprotkb:T200(gene name synonym)|uniprotkb:Leukocyte common antigen(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873789|imex:IM-13779-8083	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR006470(Formate dehydrogenase, beta subunit)|interpro:IPR014603(Formate dehydrogenase, iron-sulphur subunit)|interpro:IPR015246(Formate dehydrogenase, transmembrane)|interpro:IPR017900|go:""GO:0005886""(plasma membrane)|go:""GO:0015944""(formate oxidation)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002209611.1|interpro:IPR038384|refseq:YP_002348916.1|interpro:IPR051555"	"dip:DIP-224N|efo:""Orphanet:169157""|panther:PTHR19134(orthology-group)|ensembl:ENSG00000081237.22(gene)|ensembl:ENSG00000262418.5(gene)|ensembl:ENST00000442510.8(transcript)|ensembl:ENST00000573477.5(transcript)|ensembl:ENST00000573679.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001779""(natural killer cell differentiation)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0001960""(negative regulation of cytokine-mediated signaling pathway)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|interpro:IPR036116|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0002925""(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0006933""(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016311""(dephosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030506""(ankyrin binding)|go:""GO:0030507""(spectrin binding)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0032059""(bleb)|go:""GO:0032677""(regulation of interleukin-8 production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0042100""(B cell proliferation)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0042492""(gamma-delta T cell differentiation)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044770""(cell cycle phase transition)|go:""GO:0044855""(plasma membrane raft distribution)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045588""(positive regulation of gamma-delta T cell differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046633""(alpha-beta T cell proliferation)|go:""GO:0046641""(positive regulation of alpha-beta T cell proliferation)|go:""GO:0048304""(positive regulation of isotype switching to IgG isotypes)|go:""GO:0048539""(bone marrow development)|go:""GO:0048864""(stem cell development)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050764""(regulation of phagocytosis)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050856""(regulation of T cell receptor signaling pathway)|go:""GO:0050857""(positive regulation of antigen receptor-mediated signaling pathway)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051607""(defense response to virus)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060369""(positive regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098857""(membrane microdomain)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1902215""(negative regulation of interleukin-4-mediated signaling pathway)|go:""GO:1903979""(negative regulation of microglial cell activation)|go:""GO:1904044""(response to aldosterone)|go:""GO:1904155""(DN2 thymocyte differentiation)|go:""GO:2000473""(positive regulation of hematopoietic stem cell migration)|go:""GO:2000648""(positive regulation of stem cell proliferation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016335(Leukocyte common antigen)|interpro:IPR024739|interpro:IPR029021|interpro:IPR050348|mint:P08575|rcsb pdb:1YGR|rcsb pdb:1YGU|rcsb pdb:5FMV|rcsb pdb:5FN6|rcsb pdb:5FN7|reactome:R-HSA-202427|reactome:R-HSA-416700|reactome:R-HSA-6798695|refseq:NP_002829.3|refseq:NP_563578.2|refseq:XP_006711535.1|refseq:XP_006711536.1|refseq:XP_006711537.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qUnsGukyBMEHq2jL5PYOvQ0betE632	rogid:rrMiH60EcAzRWaaapYTjNU5+1IY9606	intact-crc:51F2B768EDA7E4A4|rigid:dOfD/CttMTTCwgxkXmdHbr4PA8s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16671	uniprotkb:Q8CZS2	intact:EBI-2808214|uniprotkb:Q9BQC2|uniprotkb:Q9BPZ8|uniprotkb:Q9BZN5|uniprotkb:Q9BZM8|uniprotkb:Q8TCV7|uniprotkb:Q9BZN3|uniprotkb:Q16093|uniprotkb:Q13966|uniprotkb:Q9BZN4|ensembl:ENSP00000308165.7|ensembl:ENSP00000378268.3|ensembl:ENSP00000399421.1|ensembl:ENSP00000411411.1|ensembl:ENSP00000415743.2|uniprotkb:D9IX66|uniprotkb:D9IX67|uniprotkb:D9IX68|uniprotkb:D9IX69	intact:EBI-2845681	psi-mi:cd36_human(display_long)|uniprotkb:GP3B(gene name synonym)|uniprotkb:GP4(gene name synonym)|uniprotkb:Platelet glycoprotein IV(gene name synonym)|uniprotkb:Glycoprotein IIIb(gene name synonym)|uniprotkb:Leukocyte differentiation antigen CD36(gene name synonym)|uniprotkb:PAS IV(gene name synonym)|uniprotkb:PAS-4(gene name synonym)|uniprotkb:Platelet collagen receptor(gene name synonym)|uniprotkb:Fatty acid translocase(gene name synonym)|uniprotkb:Thrombospondin receptor(gene name synonym)|uniprotkb:CD36(gene name)|psi-mi:CD36(display_short)	psi-mi:q8czs2_yerpe(display_long)|uniprotkb:icc(gene name)|psi-mi:icc(display_short)|uniprotkb:y3513(locus name)|uniprotkb:cpdA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873803|imex:IM-13779-8082	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000063.2|refseq:NP_001001547.1|refseq:NP_001001548.1|refseq:NP_001120915.1|refseq:NP_001120916.1|refseq:XP_005250770.1|refseq:XP_005250771.1|refseq:XP_005250772.1|ensembl:ENSG00000135218.19(gene)|ensembl:ENST00000309881.11(transcript)|ensembl:ENST00000394788.7(transcript)|ensembl:ENST00000432207.5(transcript)|ensembl:ENST00000435819.5(transcript)|ensembl:ENST00000447544.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0002532""(production of molecular mediator involved in inflammatory response)|go:""GO:0005041""(low-density lipoprotein particle receptor activity)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006910""(phagocytosis, recognition)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007155""(cell adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007596""(blood coagulation)|go:""GO:0008035""(high-density lipoprotein particle binding)|go:""GO:0008289""(lipid binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010886""(positive regulation of cholesterol storage)|go:""GO:0015636""(short-chain fatty acid transmembrane transporter activity)|go:""GO:0015908""(fatty acid transport)|go:""GO:0015909""(long-chain fatty acid transport)|go:""GO:0015911""(long-chain fatty acid import across plasma membrane)|go:""GO:0015912""(short-chain fatty acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019915""(lipid storage)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0030169""(low-density lipoprotein particle binding)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030299""(intestinal cholesterol absorption)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031092""(platelet alpha granule membrane)|go:""GO:0031526""(brush border membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0031664""(regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033993""(response to lipid)|go:""GO:0034121""(regulation of toll-like receptor signaling pathway)|go:""GO:0034197""(triglyceride transport)|go:""GO:0034381""(plasma lipoprotein particle clearance)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0035325""(Toll-like receptor binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035634""(response to stilbenoid)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0038060""(nitric oxide-cGMP-mediated signaling)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0044539""(long-chain fatty acid import into cell)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0050892""(intestinal absorption)|go:""GO:0050909""(sensory perception of taste)|go:""GO:0055096""(low-density lipoprotein particle mediated signaling)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070508""(cholesterol import)|go:""GO:0070542""(response to fatty acid)|go:""GO:0070543""(response to linoleic acid)|go:""GO:0070892""(lipoteichoic acid immune receptor activity)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071447""(cellular response to hydroperoxide)|go:""GO:0071726""(cellular response to diacyl bacterial lipopeptide)|go:""GO:0071813""(lipoprotein particle binding)|go:""GO:0071944""(cell periphery)|go:""GO:0097009""(energy homeostasis)|go:""GO:0098900""(regulation of action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140052""(cellular response to oxidised low-density lipoprotein particle stimulus)|go:""GO:0150024""(oxidised low-density lipoprotein particle clearance)|go:""GO:0150025""(oxidised low-density lipoprotein particle receptor activity)|go:""GO:0150094""(amyloid-beta clearance by cellular catabolic process)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1901480""(oleate transmembrane transporter activity)|go:""GO:1903428""(positive regulation of reactive oxygen species biosynthetic process)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990379""(lipid transport across blood-brain barrier)|go:""GO:2000121""(regulation of removal of superoxide radicals)|go:""GO:2000334""(positive regulation of blood microparticle formation)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|rcsb pdb:5LGD|reactome:R-HSA-114608|reactome:R-HSA-1236973|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-168188|reactome:R-HSA-1989781|reactome:R-HSA-3000471|reactome:R-HSA-381340|reactome:R-HSA-434313|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-9841922|refseq:NP_001276837.1|refseq:NP_001276838.1|refseq:NP_001276840.1|panther:PTHR11923(orthology-group)"	"interpro:IPR026575|interpro:IPR046379|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|go:""GO:0000166""(nucleotide binding)|go:""GO:0004115""(3',5'-cyclic-AMP phosphodiesterase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR050884"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aYX4Uyq9gXqLN3pgTWyKWGQmL5w9606	rogid:pHtA80uk66ZaIBbjEM2kYqV0pog632	intact-crc:E819060E387E5FEA|rigid:5AelMA4wJ0bTxFIJe5CBmKz4dz8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIL4	uniprotkb:P08575	intact:EBI-2852663|uniprotkb:Q0WJI3	intact:EBI-1341|uniprotkb:A8K7W6|uniprotkb:Q16614|uniprotkb:Q9H0Y6|uniprotkb:A0A0A0MT22|uniprotkb:X6R433|ensembl:ENSP00000411355.3|ensembl:ENSP00000458322.2|ensembl:ENSP00000461074.2	psi-mi:carb_yerpe(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:YPO0482(locus name)|uniprotkb:YP_3697(locus name)|uniprotkb:y3692(locus name)	psi-mi:ptprc_human(display_long)|uniprotkb:PTPRC(gene name)|psi-mi:PTPRC(display_short)|uniprotkb:CD45(gene name synonym)|uniprotkb:T200(gene name synonym)|uniprotkb:Leukocyte common antigen(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873796|imex:IM-13779-8081	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|refseq:WP_002210502.1|go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR033937|interpro:IPR036897|interpro:IPR036914|refseq:YP_002345555.1|panther:PTHR11405(orthology-group)"	"dip:DIP-224N|efo:""Orphanet:169157""|panther:PTHR19134(orthology-group)|ensembl:ENSG00000081237.22(gene)|ensembl:ENSG00000262418.5(gene)|ensembl:ENST00000442510.8(transcript)|ensembl:ENST00000573477.5(transcript)|ensembl:ENST00000573679.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001779""(natural killer cell differentiation)|go:""GO:0001915""(negative regulation of T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0001960""(negative regulation of cytokine-mediated signaling pathway)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|interpro:IPR036116|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0002925""(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005001""(transmembrane receptor protein tyrosine phosphatase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0006933""(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016311""(dephosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030506""(ankyrin binding)|go:""GO:0030507""(spectrin binding)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0032059""(bleb)|go:""GO:0032677""(regulation of interleukin-8 production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0042100""(B cell proliferation)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0042492""(gamma-delta T cell differentiation)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044770""(cell cycle phase transition)|go:""GO:0044855""(plasma membrane raft distribution)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045588""(positive regulation of gamma-delta T cell differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046633""(alpha-beta T cell proliferation)|go:""GO:0046641""(positive regulation of alpha-beta T cell proliferation)|go:""GO:0048304""(positive regulation of isotype switching to IgG isotypes)|go:""GO:0048539""(bone marrow development)|go:""GO:0048864""(stem cell development)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050764""(regulation of phagocytosis)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050856""(regulation of T cell receptor signaling pathway)|go:""GO:0050857""(positive regulation of antigen receptor-mediated signaling pathway)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051607""(defense response to virus)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060369""(positive regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098857""(membrane microdomain)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1902215""(negative regulation of interleukin-4-mediated signaling pathway)|go:""GO:1903979""(negative regulation of microglial cell activation)|go:""GO:1904044""(response to aldosterone)|go:""GO:1904155""(DN2 thymocyte differentiation)|go:""GO:2000473""(positive regulation of hematopoietic stem cell migration)|go:""GO:2000648""(positive regulation of stem cell proliferation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016335(Leukocyte common antigen)|interpro:IPR024739|interpro:IPR029021|interpro:IPR050348|mint:P08575|rcsb pdb:1YGR|rcsb pdb:1YGU|rcsb pdb:5FMV|rcsb pdb:5FN6|rcsb pdb:5FN7|reactome:R-HSA-202427|reactome:R-HSA-416700|reactome:R-HSA-6798695|refseq:NP_002829.3|refseq:NP_563578.2|refseq:XP_006711535.1|refseq:XP_006711536.1|refseq:XP_006711537.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l/RzabCD1P/dEo/AmaYoXpYV1FY632	rogid:rrMiH60EcAzRWaaapYTjNU5+1IY9606	intact-crc:B27C83F17C559DC3|rigid:i4v6dl5+AsUYxKWqf6RKWNN7/gI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13987	uniprotkb:A0A2S9PLQ4	intact:EBI-297972|ensembl:ENSP00000340210.3|ensembl:ENSP00000379191.3|ensembl:ENSP00000403511.2|ensembl:ENSP00000404822.2|ensembl:ENSP00000410182.2|ensembl:ENSP00000432942.1|ensembl:ENSP00000494884.1|ensembl:ENSP00000498448.1|ensembl:ENSP00000498879.1|uniprotkb:E9PR17	intact:EBI-2850273|uniprotkb:Q74RV3|uniprotkb:Q0WJ73|uniprotkb:Q7CGD4|uniprotkb:A0A0H2W7Y4	psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym)	psi-mi:a0a2s9plq4_yerpe(display_long)|uniprotkb:YPO0593(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873775|imex:IM-13779-8084	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:169464""|ensembl:ENSG00000085063.18(gene)|ensembl:ENST00000351554.8(transcript)|ensembl:ENST00000395850.9(transcript)|ensembl:ENST00000415002.7(transcript)|ensembl:ENST00000437761.6(transcript)|ensembl:ENST00000445143.6(transcript)|ensembl:ENST00000527577.5(transcript)|ensembl:ENST00000642928.2(transcript)|ensembl:ENST00000651785.1(transcript)|ensembl:ENST00000652678.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001848""(complement binding)|go:""GO:0001971""(negative regulation of activation of membrane attack complex)|go:""GO:0005615""(extracellular space)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007596""(blood coagulation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030133""(transport vesicle)|go:""GO:0030449""(regulation of complement activation)|go:""GO:0031982""(vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:1903659""(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR045860|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|rcsb pdb:8B0F|rcsb pdb:8B0G|rcsb pdb:8B0H|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|panther:PTHR10036(orthology-group)"	refseq:WP_002210398.1|interpro:IPR036457|refseq:YP_002345665.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606	rogid:4kqACx6zUNpUs/XEEncBiVDWpxE632	intact-crc:F5EDFCB2765C05AF|rigid:1Uf7I+j6GjO6C+1JH7aMNA8vm3s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09326	uniprotkb:A0A5P8YIF2	intact:EBI-714770|uniprotkb:Q5U055|uniprotkb:Q8MGR0|ensembl:ENSP00000357025.3	intact:EBI-2866985	psi-mi:cd48_human(display_long)|uniprotkb:B-lymphocyte activation marker BLAST-1(gene name synonym)|uniprotkb:BCM1 surface antigen(gene name synonym)|uniprotkb:Leukocyte antigen MEM-102(gene name synonym)|uniprotkb:TCT.1(gene name synonym)|uniprotkb:CD48(gene name)|psi-mi:CD48(display_short)|uniprotkb:BCM1(gene name synonym)|uniprotkb:BLAST1(gene name synonym)|uniprotkb:SLAM family member 2(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule 2(gene name synonym)	psi-mi:a0a5p8yif2_yerpe(display_long)|uniprotkb:yapA(gene name)|psi-mi:yapA(display_short)|uniprotkb:y1346(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873782|imex:IM-13779-8080	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001769.2|ensembl:ENSG00000117091.10(gene)|ensembl:ENST00000368046.8(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0016020""(membrane)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0045121""(membrane raft)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098552""(side of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015631(Signaling lymphocyte activation molecule)|interpro:IPR036179|rcsb pdb:2EDO|reactome:R-HSA-202733|panther:PTHR12080(orthology-group)"	"uniprotkb:Q8D0Z3(uniprot-removed-ac)|interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR030930|interpro:IPR036709|interpro:IPR051551|go:""GO:0019867""(outer membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IFn8oYvbQHpUpnEYAd1ss/ZfUe89606	rogid:KlFcJEuM0GDuY7337UP8lYRS3Wc632	intact-crc:7C00F73CD9958D20|rigid:aLuTHtanX189WN2tn3aOQPk4BSo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WEI1	uniprotkb:P16671	intact:EBI-2841265|uniprotkb:A0A0H2W6F6|uniprotkb:Q74TM5|uniprotkb:A0A384KVS6|uniprotkb:Q7CIQ1	intact:EBI-2808214|uniprotkb:Q9BQC2|uniprotkb:Q9BPZ8|uniprotkb:Q9BZN5|uniprotkb:Q9BZM8|uniprotkb:Q8TCV7|uniprotkb:Q9BZN3|uniprotkb:Q16093|uniprotkb:Q13966|uniprotkb:Q9BZN4|ensembl:ENSP00000308165.7|ensembl:ENSP00000378268.3|ensembl:ENSP00000399421.1|ensembl:ENSP00000411411.1|ensembl:ENSP00000415743.2|uniprotkb:D9IX66|uniprotkb:D9IX67|uniprotkb:D9IX68|uniprotkb:D9IX69	psi-mi:q0wei1_yerpe(display_long)|uniprotkb:mpaA(gene name)|psi-mi:mpaA(display_short)|uniprotkb:Gamma-D-Glu-Dap amidase(gene name synonym)|uniprotkb:Zinc metallocarboxypeptidase MpaA(gene name synonym)|uniprotkb:YPO2340(locus name)	psi-mi:cd36_human(display_long)|uniprotkb:GP3B(gene name synonym)|uniprotkb:GP4(gene name synonym)|uniprotkb:Platelet glycoprotein IV(gene name synonym)|uniprotkb:Glycoprotein IIIb(gene name synonym)|uniprotkb:Leukocyte differentiation antigen CD36(gene name synonym)|uniprotkb:PAS IV(gene name synonym)|uniprotkb:PAS-4(gene name synonym)|uniprotkb:Platelet collagen receptor(gene name synonym)|uniprotkb:Fatty acid translocase(gene name synonym)|uniprotkb:Thrombospondin receptor(gene name synonym)|uniprotkb:CD36(gene name)|psi-mi:CD36(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873823|imex:IM-13779-8088	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000834(Peptidase M14, carboxypeptidase A)|refseq:YP_002347307.1|go:""GO:0004040""(amidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009253""(peptidoglycan catabolic process)|go:""GO:0016998""(cell wall macromolecule catabolic process)|go:""GO:0061473""(murein tripeptide carboxypeptidase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR043691"	"refseq:NP_000063.2|refseq:NP_001001547.1|refseq:NP_001001548.1|refseq:NP_001120915.1|refseq:NP_001120916.1|refseq:XP_005250770.1|refseq:XP_005250771.1|refseq:XP_005250772.1|ensembl:ENSG00000135218.19(gene)|ensembl:ENST00000309881.11(transcript)|ensembl:ENST00000394788.7(transcript)|ensembl:ENST00000432207.5(transcript)|ensembl:ENST00000435819.5(transcript)|ensembl:ENST00000447544.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0002532""(production of molecular mediator involved in inflammatory response)|go:""GO:0005041""(low-density lipoprotein particle receptor activity)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006910""(phagocytosis, recognition)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007155""(cell adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007596""(blood coagulation)|go:""GO:0008035""(high-density lipoprotein particle binding)|go:""GO:0008289""(lipid binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010886""(positive regulation of cholesterol storage)|go:""GO:0015636""(short-chain fatty acid transmembrane transporter activity)|go:""GO:0015908""(fatty acid transport)|go:""GO:0015909""(long-chain fatty acid transport)|go:""GO:0015911""(long-chain fatty acid import across plasma membrane)|go:""GO:0015912""(short-chain fatty acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019915""(lipid storage)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0030169""(low-density lipoprotein particle binding)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030299""(intestinal cholesterol absorption)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031092""(platelet alpha granule membrane)|go:""GO:0031526""(brush border membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0031664""(regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033993""(response to lipid)|go:""GO:0034121""(regulation of toll-like receptor signaling pathway)|go:""GO:0034197""(triglyceride transport)|go:""GO:0034381""(plasma lipoprotein particle clearance)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0035325""(Toll-like receptor binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035634""(response to stilbenoid)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0038060""(nitric oxide-cGMP-mediated signaling)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0044539""(long-chain fatty acid import into cell)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0050892""(intestinal absorption)|go:""GO:0050909""(sensory perception of taste)|go:""GO:0055096""(low-density lipoprotein particle mediated signaling)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070508""(cholesterol import)|go:""GO:0070542""(response to fatty acid)|go:""GO:0070543""(response to linoleic acid)|go:""GO:0070892""(lipoteichoic acid immune receptor activity)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071447""(cellular response to hydroperoxide)|go:""GO:0071726""(cellular response to diacyl bacterial lipopeptide)|go:""GO:0071813""(lipoprotein particle binding)|go:""GO:0071944""(cell periphery)|go:""GO:0097009""(energy homeostasis)|go:""GO:0098900""(regulation of action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140052""(cellular response to oxidised low-density lipoprotein particle stimulus)|go:""GO:0150024""(oxidised low-density lipoprotein particle clearance)|go:""GO:0150025""(oxidised low-density lipoprotein particle receptor activity)|go:""GO:0150094""(amyloid-beta clearance by cellular catabolic process)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1901480""(oleate transmembrane transporter activity)|go:""GO:1903428""(positive regulation of reactive oxygen species biosynthetic process)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990379""(lipid transport across blood-brain barrier)|go:""GO:2000121""(regulation of removal of superoxide radicals)|go:""GO:2000334""(positive regulation of blood microparticle formation)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|rcsb pdb:5LGD|reactome:R-HSA-114608|reactome:R-HSA-1236973|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-168188|reactome:R-HSA-1989781|reactome:R-HSA-3000471|reactome:R-HSA-381340|reactome:R-HSA-434313|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-9841922|refseq:NP_001276837.1|refseq:NP_001276838.1|refseq:NP_001276840.1|panther:PTHR11923(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vZzANDo/xOIN1WVb3C3XPVZDpVU632	rogid:aYX4Uyq9gXqLN3pgTWyKWGQmL5w9606	intact-crc:A9E5ED31B09CC929|rigid:b9ucGTmazxjQxtdOuIbdq0MRzwo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZL1	uniprotkb:P16671	intact:EBI-2873813|uniprotkb:Q74QV7	intact:EBI-2808214|uniprotkb:Q9BQC2|uniprotkb:Q9BPZ8|uniprotkb:Q9BZN5|uniprotkb:Q9BZM8|uniprotkb:Q8TCV7|uniprotkb:Q9BZN3|uniprotkb:Q16093|uniprotkb:Q13966|uniprotkb:Q9BZN4|ensembl:ENSP00000308165.7|ensembl:ENSP00000378268.3|ensembl:ENSP00000399421.1|ensembl:ENSP00000411411.1|ensembl:ENSP00000415743.2|uniprotkb:D9IX66|uniprotkb:D9IX67|uniprotkb:D9IX68|uniprotkb:D9IX69	psi-mi:q8czl1_yerpe(display_long)|uniprotkb:yapE(gene name)|psi-mi:yapE(display_short)|uniprotkb:YP_3347(locus name)|uniprotkb:y3845(locus name)	psi-mi:cd36_human(display_long)|uniprotkb:GP3B(gene name synonym)|uniprotkb:GP4(gene name synonym)|uniprotkb:Platelet glycoprotein IV(gene name synonym)|uniprotkb:Glycoprotein IIIb(gene name synonym)|uniprotkb:Leukocyte differentiation antigen CD36(gene name synonym)|uniprotkb:PAS IV(gene name synonym)|uniprotkb:PAS-4(gene name synonym)|uniprotkb:Platelet collagen receptor(gene name synonym)|uniprotkb:Fatty acid translocase(gene name synonym)|uniprotkb:Thrombospondin receptor(gene name synonym)|uniprotkb:CD36(gene name)|psi-mi:CD36(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873810|imex:IM-13779-8085	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|go:""GO:0019867""(outer membrane)|interpro:IPR051551|interpro:IPR043990"	"refseq:NP_000063.2|refseq:NP_001001547.1|refseq:NP_001001548.1|refseq:NP_001120915.1|refseq:NP_001120916.1|refseq:XP_005250770.1|refseq:XP_005250771.1|refseq:XP_005250772.1|ensembl:ENSG00000135218.19(gene)|ensembl:ENST00000309881.11(transcript)|ensembl:ENST00000394788.7(transcript)|ensembl:ENST00000432207.5(transcript)|ensembl:ENST00000435819.5(transcript)|ensembl:ENST00000447544.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0002532""(production of molecular mediator involved in inflammatory response)|go:""GO:0005041""(low-density lipoprotein particle receptor activity)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006910""(phagocytosis, recognition)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007155""(cell adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007596""(blood coagulation)|go:""GO:0008035""(high-density lipoprotein particle binding)|go:""GO:0008289""(lipid binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010886""(positive regulation of cholesterol storage)|go:""GO:0015636""(short-chain fatty acid transmembrane transporter activity)|go:""GO:0015908""(fatty acid transport)|go:""GO:0015909""(long-chain fatty acid transport)|go:""GO:0015911""(long-chain fatty acid import across plasma membrane)|go:""GO:0015912""(short-chain fatty acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019915""(lipid storage)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0030169""(low-density lipoprotein particle binding)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030299""(intestinal cholesterol absorption)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031092""(platelet alpha granule membrane)|go:""GO:0031526""(brush border membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0031664""(regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033993""(response to lipid)|go:""GO:0034121""(regulation of toll-like receptor signaling pathway)|go:""GO:0034197""(triglyceride transport)|go:""GO:0034381""(plasma lipoprotein particle clearance)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0035325""(Toll-like receptor binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035634""(response to stilbenoid)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0038060""(nitric oxide-cGMP-mediated signaling)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0044539""(long-chain fatty acid import into cell)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0050892""(intestinal absorption)|go:""GO:0050909""(sensory perception of taste)|go:""GO:0055096""(low-density lipoprotein particle mediated signaling)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070508""(cholesterol import)|go:""GO:0070542""(response to fatty acid)|go:""GO:0070543""(response to linoleic acid)|go:""GO:0070892""(lipoteichoic acid immune receptor activity)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071447""(cellular response to hydroperoxide)|go:""GO:0071726""(cellular response to diacyl bacterial lipopeptide)|go:""GO:0071813""(lipoprotein particle binding)|go:""GO:0071944""(cell periphery)|go:""GO:0097009""(energy homeostasis)|go:""GO:0098900""(regulation of action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140052""(cellular response to oxidised low-density lipoprotein particle stimulus)|go:""GO:0150024""(oxidised low-density lipoprotein particle clearance)|go:""GO:0150025""(oxidised low-density lipoprotein particle receptor activity)|go:""GO:0150094""(amyloid-beta clearance by cellular catabolic process)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1901480""(oleate transmembrane transporter activity)|go:""GO:1903428""(positive regulation of reactive oxygen species biosynthetic process)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990379""(lipid transport across blood-brain barrier)|go:""GO:2000121""(regulation of removal of superoxide radicals)|go:""GO:2000334""(positive regulation of blood microparticle formation)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|rcsb pdb:5LGD|reactome:R-HSA-114608|reactome:R-HSA-1236973|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-168188|reactome:R-HSA-1989781|reactome:R-HSA-3000471|reactome:R-HSA-381340|reactome:R-HSA-434313|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-9841922|refseq:NP_001276837.1|refseq:NP_001276838.1|refseq:NP_001276840.1|panther:PTHR11923(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8C226Vpdj3N30d3Z1c67M8Lw2ws632	rogid:aYX4Uyq9gXqLN3pgTWyKWGQmL5w9606	intact-crc:05D6060E389DE091|rigid:zL5UNA5zWwVALLcxakqGyk/jTVk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PHG4	uniprotkb:P20273	intact:EBI-2846487|uniprotkb:Q74Y91|uniprotkb:Q7CLC1|uniprotkb:A0A5P8YL17|uniprotkb:A0A0H2W0U8	intact:EBI-78277|uniprotkb:O95699|uniprotkb:O95701|uniprotkb:O95702|uniprotkb:O95703|uniprotkb:Q01665|uniprotkb:Q92872|uniprotkb:Q92873|uniprotkb:Q9UQA6|uniprotkb:Q9UQA7|uniprotkb:Q9UQA8|uniprotkb:Q9UQA9|uniprotkb:Q9UQB0|uniprotkb:Q9Y2A6|uniprotkb:Q32M46|uniprotkb:F5H7U3|uniprotkb:F5GYU4|ensembl:ENSP00000085219.4	psi-mi:a0a2s9phg4_yerpe(display_long)|uniprotkb:cpxA(gene name)|psi-mi:cpxA(display_short)|uniprotkb:YPO0073(locus name)	psi-mi:cd22_human(display_long)|uniprotkb:CD22(gene name)|psi-mi:CD22(display_short)|uniprotkb:Sialic acid-binding Ig-like lectin 2(gene name synonym)|uniprotkb:T-cell surface antigen Leu-14(gene name synonym)|uniprotkb:B-lymphocyte cell adhesion molecule(gene name synonym)|uniprotkb:SIGLEC2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873849|imex:IM-13779-8089	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005886""(plasma membrane)|interpro:IPR032404|interpro:IPR038515|interpro:IPR036097|interpro:IPR036890|refseq:WP_002208971.1|refseq:YP_002345167.1|interpro:IPR050398"	"refseq:NP_001172028.1|refseq:NP_001172029.1|refseq:NP_001172030.1|refseq:NP_001762.2|panther:PTHR46958(orthology-group)|refseq:NP_001265346.1|ensembl:ENSG00000012124.17(gene)|ensembl:ENST00000085219.10(transcript)|go:""GO:0001791""(IgM binding)|go:""GO:0002638""(negative regulation of immunoglobulin production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030888""(regulation of B cell proliferation)|go:""GO:0032809""(neuronal cell body membrane)|go:""GO:0033691""(sialic acid binding)|go:""GO:0042113""(B cell activation)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0050776""(regulation of immune response)|go:""GO:0050849""(negative regulation of calcium-mediated signaling)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P20273|rcsb pdb:5VKJ|rcsb pdb:5VKM|rcsb pdb:5VL3|rcsb pdb:7O52|reactome:R-HSA-198933|reactome:R-HSA-5690714|reactome:R-HSA-983695"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:g3ZbRmxqWvzTKwK/jxKgrWUTXrU632	rogid:oW0fQLFE0bGlTEig2FuboCYuLag9606	intact-crc:E0446C2EFE7756EB|rigid:t2YRMr3jTdOxIg1a9LYLwt/zatM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0A6	uniprotkb:Q9NPF0	intact:EBI-2873840|uniprotkb:Q74UW5	intact:EBI-1054562|uniprotkb:Q53HF7|uniprotkb:B2RDS5|uniprotkb:D6W668|uniprotkb:F5H6D3|ensembl:ENSP00000301458.4	psi-mi:q8d0a6_yerpe(display_long)|uniprotkb:mglA5(gene name)|psi-mi:mglA5(display_short)|uniprotkb:YP_1579(locus name)|uniprotkb:y2493(locus name)	psi-mi:cd320_human(display_long)|uniprotkb:8D6 antigen(gene name synonym)|uniprotkb:FDC-signaling molecule 8D6(gene name synonym)|uniprotkb:CD320(gene name)|psi-mi:CD320(display_short)|uniprotkb:8D6A(gene name synonym)|uniprotkb:UNQ198/PRO224(orf name)|uniprotkb:Transcobalamin receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873837|imex:IM-13779-8087	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR050107"	"efo:""Orphanet:280183""|ensembl:ENSG00000167775.11(gene)|ensembl:ENST00000301458.10(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0008083""(growth factor activity)|go:""GO:0015889""(cobalamin transport)|go:""GO:0016020""(membrane)|go:""GO:0021517""(ventral spinal cord development)|go:""GO:0030656""(regulation of vitamin metabolic process)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031296""(B cell costimulation)|go:""GO:0031419""(cobalamin binding)|go:""GO:0038024""(cargo receptor activity)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR036055|interpro:IPR050685|rcsb pdb:4ZRP|rcsb pdb:4ZRQ|rcsb pdb:7QBD|rcsb pdb:7QBE|rcsb pdb:7QBF|rcsb pdb:7QBG|reactome:R-HSA-3359485|reactome:R-HSA-9758890|refseq:NP_001159367.1|refseq:NP_057663.1|panther:PTHR24270(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dJCvUzlxnH0uD2SGwIG0oWm+8qA632	rogid:NmkWZ/6zeAq8s5vkkJmOnVLYzsM9606	intact-crc:528CCCB34A800FEE|rigid:1TcBqJupNKhvxtYsktT2T0ycytE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16671	uniprotkb:Q74XD3	intact:EBI-2808214|uniprotkb:Q9BQC2|uniprotkb:Q9BPZ8|uniprotkb:Q9BZN5|uniprotkb:Q9BZM8|uniprotkb:Q8TCV7|uniprotkb:Q9BZN3|uniprotkb:Q16093|uniprotkb:Q13966|uniprotkb:Q9BZN4|ensembl:ENSP00000308165.7|ensembl:ENSP00000378268.3|ensembl:ENSP00000399421.1|ensembl:ENSP00000411411.1|ensembl:ENSP00000415743.2|uniprotkb:D9IX66|uniprotkb:D9IX67|uniprotkb:D9IX68|uniprotkb:D9IX69	intact:EBI-2855960|uniprotkb:Q8ZIY8|uniprotkb:Q0WJW4|uniprotkb:Q7CKN0	psi-mi:cd36_human(display_long)|uniprotkb:GP3B(gene name synonym)|uniprotkb:GP4(gene name synonym)|uniprotkb:Platelet glycoprotein IV(gene name synonym)|uniprotkb:Glycoprotein IIIb(gene name synonym)|uniprotkb:Leukocyte differentiation antigen CD36(gene name synonym)|uniprotkb:PAS IV(gene name synonym)|uniprotkb:PAS-4(gene name synonym)|uniprotkb:Platelet collagen receptor(gene name synonym)|uniprotkb:Fatty acid translocase(gene name synonym)|uniprotkb:Thrombospondin receptor(gene name synonym)|uniprotkb:CD36(gene name)|psi-mi:CD36(display_short)	psi-mi:cuta_yerpe(display_long)|uniprotkb:cutA(gene name)|psi-mi:cutA(display_short)|uniprotkb:YPO0346(locus name)|uniprotkb:y0604(locus name)|uniprotkb:YP_0500(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873830|imex:IM-13779-8086	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000063.2|refseq:NP_001001547.1|refseq:NP_001001548.1|refseq:NP_001120915.1|refseq:NP_001120916.1|refseq:XP_005250770.1|refseq:XP_005250771.1|refseq:XP_005250772.1|ensembl:ENSG00000135218.19(gene)|ensembl:ENST00000309881.11(transcript)|ensembl:ENST00000394788.7(transcript)|ensembl:ENST00000432207.5(transcript)|ensembl:ENST00000435819.5(transcript)|ensembl:ENST00000447544.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0002532""(production of molecular mediator involved in inflammatory response)|go:""GO:0005041""(low-density lipoprotein particle receptor activity)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005324""(long-chain fatty acid transmembrane transporter activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006910""(phagocytosis, recognition)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007155""(cell adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007596""(blood coagulation)|go:""GO:0008035""(high-density lipoprotein particle binding)|go:""GO:0008289""(lipid binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010886""(positive regulation of cholesterol storage)|go:""GO:0015636""(short-chain fatty acid transmembrane transporter activity)|go:""GO:0015908""(fatty acid transport)|go:""GO:0015909""(long-chain fatty acid transport)|go:""GO:0015911""(long-chain fatty acid import across plasma membrane)|go:""GO:0015912""(short-chain fatty acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019915""(lipid storage)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0030169""(low-density lipoprotein particle binding)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030299""(intestinal cholesterol absorption)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031092""(platelet alpha granule membrane)|go:""GO:0031526""(brush border membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0031664""(regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0033993""(response to lipid)|go:""GO:0034121""(regulation of toll-like receptor signaling pathway)|go:""GO:0034197""(triglyceride transport)|go:""GO:0034381""(plasma lipoprotein particle clearance)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0035325""(Toll-like receptor binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035634""(response to stilbenoid)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0038060""(nitric oxide-cGMP-mediated signaling)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0044539""(long-chain fatty acid import into cell)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0050892""(intestinal absorption)|go:""GO:0050909""(sensory perception of taste)|go:""GO:0055096""(low-density lipoprotein particle mediated signaling)|go:""GO:0060100""(positive regulation of phagocytosis, engulfment)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0070053""(thrombospondin receptor activity)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070508""(cholesterol import)|go:""GO:0070542""(response to fatty acid)|go:""GO:0070543""(response to linoleic acid)|go:""GO:0070892""(lipoteichoic acid immune receptor activity)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071447""(cellular response to hydroperoxide)|go:""GO:0071726""(cellular response to diacyl bacterial lipopeptide)|go:""GO:0071813""(lipoprotein particle binding)|go:""GO:0071944""(cell periphery)|go:""GO:0097009""(energy homeostasis)|go:""GO:0098900""(regulation of action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140052""(cellular response to oxidised low-density lipoprotein particle stimulus)|go:""GO:0150024""(oxidised low-density lipoprotein particle clearance)|go:""GO:0150025""(oxidised low-density lipoprotein particle receptor activity)|go:""GO:0150094""(amyloid-beta clearance by cellular catabolic process)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1901480""(oleate transmembrane transporter activity)|go:""GO:1903428""(positive regulation of reactive oxygen species biosynthetic process)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990379""(lipid transport across blood-brain barrier)|go:""GO:2000121""(regulation of removal of superoxide radicals)|go:""GO:2000334""(positive regulation of blood microparticle formation)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|rcsb pdb:5LGD|reactome:R-HSA-114608|reactome:R-HSA-1236973|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-168188|reactome:R-HSA-1989781|reactome:R-HSA-3000471|reactome:R-HSA-381340|reactome:R-HSA-434313|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-9841922|refseq:NP_001276837.1|refseq:NP_001276838.1|refseq:NP_001276840.1|panther:PTHR11923(orthology-group)"	"refseq:WP_002209122.1|interpro:IPR023700|interpro:IPR004323(Divalent ion tolerance protein, CutA1)|interpro:IPR011322(Nitrogen regulatory PII-like, alpha/beta)|rcsb pdb:3GSD|interpro:IPR015867(Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal)|go:""GO:0005507""(copper ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0010038""(response to metal ion)|refseq:YP_002345424.1|panther:PTHR23419(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aYX4Uyq9gXqLN3pgTWyKWGQmL5w9606	rogid:oZ+dqE3f5QFb+ouShZmMFoGk+4Q632	intact-crc:F07CC9F0E726F932|rigid:rgQ7EFOn066eKg7qY3rQX1OJaUo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W496	uniprotkb:P78312	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	intact:EBI-2873877|uniprotkb:P78313|uniprotkb:P78311|uniprotkb:Q9UEG8|uniprotkb:O43607|ensembl:ENSP00000324587.5|uniprotkb:B7ZM85|uniprotkb:E9PFA1|uniprotkb:B9EGR0	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	psi-mi:f193a_human(display_long)|uniprotkb:FAM193A(gene name)|psi-mi:FAM193A(display_short)|uniprotkb:C4orf8(gene name synonym)|uniprotkb:Protein IT14(gene name synonym)|uniprotkb:RES4-22(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873886|imex:IM-13779-8093	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	refseq:NP_003695.3|ensembl:ENSG00000125386.16(gene)|ensembl:ENST00000324666.9(transcript)|interpro:IPR029717|interpro:IPR031802|refseq:NP_001243595.1|refseq:NP_001243596.1|refseq:NP_001243597.1|refseq:XP_006713993.2|panther:PTHR15109(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	rogid:v0yZQ433SbBvEWkvwuNSZNebaD09606	intact-crc:CC8713085F0F6820|rigid:/73nofR1q71YdmMYLSqzNiFfGcI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YGL8	uniprotkb:Q68CZ6	intact:EBI-2845909|uniprotkb:Q74VS1|uniprotkb:Q0WH41|uniprotkb:Q7CHI6|uniprotkb:A0A384L3E0	intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706.4|ensembl:ENSP00000392903.2|uniprotkb:B4DF64	psi-mi:a0a5p8ygl8_yerpe(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:YPO1374(locus name)	psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873870|imex:IM-13779-8091	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0019430""(removal of superoxide radicals)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_002211341.1|interpro:IPR036188|refseq:YP_002346397.1|interpro:IPR050097|panther:PTHR48105(orthology-group)"	"refseq:NP_078787.2|ensembl:ENSG00000214367.10(gene)|ensembl:ENST00000243706.8(transcript)|ensembl:ENST00000443786.3(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0007098""(centrosome cycle)|go:""GO:0010968""(regulation of microtubule nucleation)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0051225""(spindle assembly)|go:""GO:0051301""(cell division)|go:""GO:0070652""(HAUS complex)|go:""GO:0072686""(mitotic spindle)|go:""GO:1990498""(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:7SQK|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N|panther:PTHR19378(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/05	rogid:lNjtMW37Ur6Z7pzA6LzMVzq9VCU632	rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606	intact-crc:1B83F97DECE95C9B|rigid:izd/BGRFocvV0wKxy3s2WBgBQkw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P28808	uniprotkb:Q9NXF7	intact:EBI-2860941	intact:EBI-2559096|ensembl:ENSP00000371682.1|uniprotkb:B3KPB7	psi-mi:lcrf_yerpe(display_long)|uniprotkb:lcrF(gene name)|psi-mi:lcrF(display_short)|uniprotkb:virF(gene name synonym)|uniprotkb:YPCD1.49(locus name)|uniprotkb:y5029(locus name)|uniprotkb:y0032(locus name)|uniprotkb:YP_pCD34(locus name)	psi-mi:dca16_human(display_long)|uniprotkb:DCAF16(gene name)|psi-mi:DCAF16(display_short)|uniprotkb:C4orf30(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873863|imex:IM-13779-8090	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395183.1|refseq:NP_857733.1|refseq:NP_857928.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR018062|interpro:IPR018060|interpro:IPR020449|interpro:IPR054015|mint:P28808|refseq:WP_002212931.1|interpro:IPR050204|interpro:IPR037923|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0043565""(sequence-specific DNA binding)|panther:PTHR43280(orthology-group)"	"ensembl:ENSG00000163257.11(gene)|ensembl:ENST00000382247.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR028216|mint:Q9NXF7|rcsb pdb:8G46|rcsb pdb:8OV6|reactome:R-HSA-8951664|refseq:NP_060211.3|refseq:NP_001332809.1|refseq:NP_001332810.1|refseq:NP_001332811.1|refseq:NP_001332813.1|refseq:NP_001332814.1|refseq:XP_016863816.1|refseq:XP_016863817.1|panther:PTHR16194(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yVpO1P2FvEEro9oVZYYjR90kz/M632	rogid:nw3uabUDsivZMGy04ZZolwJmdeI9606	intact-crc:EA23D15BDA671A7D|rigid:F2NvjHiXolIWR0cMJmFeQ3vkByw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11836	uniprotkb:Q8ZE20	intact:EBI-2808234|uniprotkb:A6NMS4|uniprotkb:P08984|uniprotkb:Q13963|uniprotkb:B4DT24|ensembl:ENSP00000314620.7|ensembl:ENSP00000374589.2|ensembl:ENSP00000433277.1|ensembl:ENSP00000501369.1	intact:EBI-2857666|uniprotkb:Q74TK0|uniprotkb:Q0WEF3|uniprotkb:Q8D0L4	psi-mi:cd20_human(display_long)|uniprotkb:MS4A1(gene name)|psi-mi:MS4A1(display_short)|uniprotkb:CD20(gene name synonym)|uniprotkb:B-lymphocyte surface antigen B1(gene name synonym)|uniprotkb:Bp35(gene name synonym)|uniprotkb:Leukocyte surface antigen Leu-16(gene name synonym)|uniprotkb:Membrane-spanning 4-domains subfamily A member 1(gene name synonym)	psi-mi:syy_yerpe(display_long)|uniprotkb:tyrS(gene name)|psi-mi:tyrS(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO2369(locus name)|uniprotkb:YP_2155(locus name)|uniprotkb:y1966(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873856|imex:IM-13779-8092	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000156738.18(gene)|ensembl:ENST00000345732.9(transcript)|ensembl:ENST00000389939.2(transcript)|ensembl:ENST00000534668.6(transcript)|ensembl:ENST00000674194.1(transcript)|go:""GO:0002115""(store-operated calcium entry)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006959""(humoral immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009617""(response to bacterium)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0042100""(B cell proliferation)|go:""GO:0042113""(B cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051262""(protein tetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902656""(calcium ion import into cytosol)|go:""GO:1905665""(positive regulation of calcium ion import across plasma membrane)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|mint:P11836|rcsb pdb:2OSL|rcsb pdb:3BKY|rcsb pdb:3PP4|rcsb pdb:6VJA|rcsb pdb:6Y90|rcsb pdb:6Y92|rcsb pdb:6Y97|rcsb pdb:6Y9A|refseq:NP_068769.2|refseq:NP_690605.1|efo:""Orphanet:1572""|panther:PTHR23320(orthology-group)"	"interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002942(RNA-binding S4)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR024088|interpro:IPR024107|refseq:WP_002210960.1|go:""GO:0003723""(RNA binding)|go:""GO:0004831""(tyrosine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006437""(tyrosyl-tRNA aminoacylation)|go:""GO:0043039""(tRNA aminoacylation)|interpro:IPR054608|interpro:IPR036986|refseq:YP_002347335.1|panther:PTHR11766(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AnlKRZ3H77etWyyZIldbXkJDRkk9606	rogid:BUagKLSbiLvLgJHoonFfm7nI4ss632	intact-crc:0B7AB69ABF425B0E|rigid:/4OcXiNMCnzN9VQz8EcrS9gEjoE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W6Y0	uniprotkb:Q9ULG6	intact:EBI-2851229	intact:EBI-2873893|intact:EBI-28979549|uniprotkb:Q8IYV8|uniprotkb:Q9BY53|uniprotkb:A0PJH3|uniprotkb:Q05DG4|uniprotkb:O14712|uniprotkb:Q5U5S7|uniprotkb:Q9HA17|ensembl:ENSP00000311656.6|ensembl:ENSP00000454456.1|uniprotkb:A8K9T0	psi-mi:a0a0h2w6y0_yerpe(display_long)|uniprotkb:NCTC5923_03272(orf name)|uniprotkb:YP_2938(locus name)|uniprotkb:y3557(locus name)	psi-mi:ccpg1_human(display_long)|uniprotkb:CCPG1(gene name)|psi-mi:CCPG1(display_short)|uniprotkb:CCP8(gene name synonym)|uniprotkb:CPR8(gene name synonym)|uniprotkb:KIAA1254(gene name synonym)|uniprotkb:Cell cycle progression restoration protein 8(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873904|imex:IM-13779-8098	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031381|uniprotkb:A0A6B3T0Z7(uniprot-removed-ac)|go:""GO:0005886""(plasma membrane)|refseq:WP_002214224.1"	"refseq:NP_001191380.1|refseq:NP_004739.3|refseq:NP_065790.2|ensembl:ENSG00000260916.8(gene)|ensembl:ENST00000310958.10(transcript)|ensembl:ENST00000569205.5(transcript)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR051990|mint:Q9ULG6|rcsb pdb:7D0E|refseq:NP_001191379.1|panther:PTHR28638(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jpemEe1g8Pg5hCUGcqrXm8QtFic632	rogid:jAMOJsrn4wr2TnlJzGyAyQp25989606	intact-crc:A9ABCA08562A0FE4|rigid:cigSgzzDxEDeLpeKa7wuROcSAJM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG8	uniprotkb:P24863	intact:EBI-2849252|uniprotkb:Q0WIB1	intact:EBI-395261|uniprotkb:Q9H543|uniprotkb:B4DPZ1|ensembl:ENSP00000428982.1	psi-mi:spea_yerpe(display_long)|uniprotkb:speA(gene name)|psi-mi:speA(display_short)|uniprotkb:YPO0929(locus name)|uniprotkb:y3313(locus name)|uniprotkb:YP_3513(locus name)	psi-mi:ccnc_human(display_long)|uniprotkb:CCNC(gene name)|psi-mi:CCNC(display_short)|uniprotkb:SRB11 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873925|imex:IM-13779-8095	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR002985(Arginine decarboxylase)|interpro:IPR022657|interpro:IPR022644|interpro:IPR022653|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|interpro:IPR029066|interpro:IPR040634|go:""GO:0006527""(arginine catabolic process)|go:""GO:0008295""(spermidine biosynthetic process)|go:""GO:0008792""(arginine decarboxylase activity)|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0046872""(metal ion binding)|interpro:IPR041128|refseq:WP_002209969.1|refseq:YP_002345977.1|panther:PTHR43295(orthology-group)"	"refseq:NP_005181.2|refseq:NP_001013417.1|ensembl:ENSG00000112237.13(gene)|ensembl:ENST00000520429.6(transcript)|go:""GO:0000307""(cyclin-dependent protein kinase holoenzyme complex)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016538""(cyclin-dependent protein serine/threonine kinase regulator activity)|go:""GO:0016592""(mediator complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0045023""(G0 to G1 transition)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1990508""(CKM complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|mint:P24863|rcsb pdb:3RGF|rcsb pdb:4CRL|rcsb pdb:4F6S|rcsb pdb:4F6U|rcsb pdb:4F6W|rcsb pdb:4F70|rcsb pdb:4F7J|rcsb pdb:4F7L|rcsb pdb:4F7N|rcsb pdb:4F7S|rcsb pdb:4G6L|rcsb pdb:5BNJ|rcsb pdb:5CEI|rcsb pdb:5FGK|rcsb pdb:5HBE|rcsb pdb:5HBH|rcsb pdb:5HBJ|rcsb pdb:5HNB|rcsb pdb:5HVY|rcsb pdb:5I5Z|rcsb pdb:5ICP|rcsb pdb:5IDN|rcsb pdb:5IDP|rcsb pdb:5XQX|rcsb pdb:5XS2|rcsb pdb:6QTG|rcsb pdb:6QTJ|rcsb pdb:6R3S|rcsb pdb:6T41|rcsb pdb:6TPA|rcsb pdb:6Y0A|rcsb pdb:8TQ2|rcsb pdb:8TQC|rcsb pdb:8TQW|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-212436|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|dip:DIP-32920N|panther:PTHR10026(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:WJK/NuC1y1WJhbzgBDwly+QaYwA632	rogid:Gu327q98H8ggQoYCb4UnR2Mcsyg9606	intact-crc:34C52E6F80017D41|rigid:Fn3Mw3pUs5fwKmntKxY9sJh5b88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13501	uniprotkb:Q8D0E1	intact:EBI-2848366|uniprotkb:Q0QVW8|uniprotkb:O43646|uniprotkb:Q9NYA2|uniprotkb:Q9UBG2|uniprotkb:Q9UC99|uniprotkb:Q4ZGJ1|ensembl:ENSP00000474141.2|ensembl:ENSP00000475057.1|ensembl:ENSP00000479894.1|ensembl:ENSP00000484921.2	intact:EBI-2851171	psi-mi:ccl5_human(display_long)|uniprotkb:CCL5(gene name)|psi-mi:CCL5(display_short)|uniprotkb:D17S136E(gene name synonym)|uniprotkb:SCYA5(gene name synonym)|uniprotkb:EoCP(gene name synonym)|uniprotkb:Eosinophil chemotactic cytokine(gene name synonym)|uniprotkb:SIS-delta(gene name synonym)|uniprotkb:Small-inducible cytokine A5(gene name synonym)|uniprotkb:T cell-specific protein P228(gene name synonym)|uniprotkb:T-cell-specific protein RANTES(gene name synonym)	psi-mi:q8d0e1_yerpe(display_long)|uniprotkb:y2338(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873932|imex:IM-13779-8096	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002976.2|ensembl:ENSG00000271503.7(gene)|ensembl:ENSG00000274233.4(gene)|ensembl:ENST00000605140.6(transcript)|ensembl:ENST00000605509.2(transcript)|ensembl:ENST00000613606.2(transcript)|ensembl:ENST00000618639.4(transcript)|go:""GO:0002407""(dendritic cell chemotaxis)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002676""(regulation of chronic inflammatory response)|go:""GO:0004435""(phosphatidylinositol-4,5-bisphosphate phospholipase C activity)|go:""GO:0004672""(protein kinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006887""(exocytosis)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008009""(chemokine activity)|go:""GO:0009615""(response to virus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010820""(positive regulation of T cell chemotaxis)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0030298""(receptor signaling protein tyrosine kinase activator activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031328""(obsolete positive regulation of cellular biosynthetic process)|go:""GO:0031584""(activation of phospholipase D activity)|go:""GO:0031726""(CCR1 chemokine receptor binding)|go:""GO:0031729""(CCR4 chemokine receptor binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0033634""(positive regulation of cell-cell adhesion mediated by integrin)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035689""(""chemokine (C-C motif) ligand 5 signaling pathway"")|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042379""(chemokine receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046817""(chemokine receptor antagonist activity)|go:""GO:0048020""(CCR chemokine receptor binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0050863""(regulation of T cell activation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:0070234""(positive regulation of T cell apoptotic process)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|go:""GO:0097696""(cell surface receptor signaling pathway via STAT)|go:""GO:0098586""(cellular response to virus)|go:""GO:1904894""(positive regulation of receptor signaling pathway via STAT)|go:""GO:2000110""(negative regulation of macrophage apoptotic process)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000503""(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|mint:P13501|rcsb pdb:1B3A|rcsb pdb:1EQT|rcsb pdb:1HRJ|rcsb pdb:1RTN|rcsb pdb:1RTO|rcsb pdb:1U4L|rcsb pdb:1U4M|rcsb pdb:1U4P|rcsb pdb:1U4R|rcsb pdb:2L9H|rcsb pdb:2VXW|rcsb pdb:5CMD|rcsb pdb:5COY|rcsb pdb:5DNF|rcsb pdb:5L2U|rcsb pdb:5UIW|rcsb pdb:6AEZ|rcsb pdb:6C6D|rcsb pdb:6FGP|rcsb pdb:6LOG|rcsb pdb:6STK|rcsb pdb:7F1R|rcsb pdb:7O7F|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|dip:DIP-31N|panther:PTHR12015(orthology-group)"	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR010252(Formiminoglutamate deiminase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR032466|go:""GO:0016810""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"")|interpro:IPR051607"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ax9zuZGIpTIg8FnZi3cyCG+C+kQ9606	rogid:PERKzynzhTOYlkTaHwhsilRxm0U632	intact-crc:A09CF5DC521228CE|rigid:h6xiPoved34MQpAtJ7lirA/rJBg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P42713	uniprotkb:Q9UK58	intact:EBI-2855318	intact:EBI-2836773|uniprotkb:B3KMY3|uniprotkb:Q96QT0|uniprotkb:Q9NZF3|uniprotkb:Q8NI48|uniprotkb:Q6NVY9|uniprotkb:Q6UWS7|ensembl:ENSP00000295926.4|intact:EBI-11158173|uniprotkb:C9JPL0	psi-mi:yscq_yerpe(display_long)|uniprotkb:yscQ(gene name)|psi-mi:yscQ(display_short)|uniprotkb:YPCD1.43(locus name)|uniprotkb:y5035(locus name)|uniprotkb:y0038(locus name)|uniprotkb:YP_pCD40(locus name)	psi-mi:ccnl1_human(display_long)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873911|imex:IM-13779-8094	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395177.1|refseq:NP_857739.1|refseq:NP_857934.1|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|interpro:IPR003283(Type III secretion system outer membrane O protein)|interpro:IPR013385(Type III secretion system apparatus protein YscQ/HrcQ)|refseq:WP_002212948.1|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0071978""(bacterial-type flagellum-dependent swarming motility)|interpro:IPR036429|panther:PTHR30034(orthology-group)"	"ensembl:ENSG00000163660.12(gene)|ensembl:ENST00000295926.8(transcript)|go:""GO:0000307""(cyclin-dependent protein kinase holoenzyme complex)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016538""(cyclin-dependent protein serine/threonine kinase regulator activity)|go:""GO:0016607""(nuclear speck)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0046605""(regulation of centrosome cycle)|go:""GO:0051726""(regulation of cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|mint:Q9UK58|refseq:NP_064703.1|refseq:NP_001295114.1|refseq:XP_016862381.1|refseq:XP_016862382.1|refseq:XP_016862383.1|refseq:XP_016862384.1|refseq:XP_016862385.1|panther:PTHR10026(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6QCEVIThofNCQV+S/cN32USA1WE632	rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606	intact-crc:FE1D43677F3A5286|rigid:HQ1GHnZUcw0wyDRfVfj9FO9iTjQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40127	uniprotkb:Q14094	intact:EBI-2844091|uniprotkb:Q0WAG2	intact:EBI-1104653|uniprotkb:B2R6M0|uniprotkb:B7Z6X4|ensembl:ENSP00000237654.4	psi-mi:cyaa_yerpe(display_long)|uniprotkb:cya(gene name)|psi-mi:cya(display_short)|uniprotkb:cyaA(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:YPO3848(locus name)|uniprotkb:y0382(locus name)|uniprotkb:YP_3199(locus name)	psi-mi:ccni_human(display_long)|uniprotkb:CCNI(gene name)|psi-mi:CCNI(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873918|imex:IM-13779-8097	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000274(Adenylate cyclase, class-I)|interpro:IPR024686|interpro:IPR024685|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006171""(cAMP biosynthetic process)|refseq:WP_002211468.1|refseq:YP_002348726.1|panther:PTHR38760(orthology-group)"	"refseq:NP_001335061.1|refseq:NP_001335062.1|refseq:NP_001335063.1|refseq:NP_006826.1|ensembl:ENSG00000118816.12(gene)|ensembl:ENST00000237654.9(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000307""(cyclin-dependent protein kinase holoenzyme complex)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016538""(cyclin-dependent protein serine/threonine kinase regulator activity)|go:""GO:0031965""(nuclear membrane)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:Q14094|panther:PTHR10177(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l0RzY0/qkJ4UmTdMusK/+DQB0ow632	rogid:lsO+Zg9Xf/S6JoMy7kmo4IT9Nts9606	intact-crc:3873ACE912D1D806|rigid:2GJuSM8WYm/866MHfz7Ut+ELGiY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H4G8	uniprotkb:P13501	intact:EBI-2853974|uniprotkb:Q74QW2|uniprotkb:Q0WA39|uniprotkb:A0A5P8YAW1|uniprotkb:Q7CG08|uniprotkb:A0A384KLT9	intact:EBI-2848366|uniprotkb:Q0QVW8|uniprotkb:O43646|uniprotkb:Q9NYA2|uniprotkb:Q9UBG2|uniprotkb:Q9UC99|uniprotkb:Q4ZGJ1|ensembl:ENSP00000474141.2|ensembl:ENSP00000475057.1|ensembl:ENSP00000479894.1|ensembl:ENSP00000484921.2	psi-mi:a0a2u2h4g8_yerpe(display_long)|uniprotkb:YPO3979(locus name)	psi-mi:ccl5_human(display_long)|uniprotkb:CCL5(gene name)|psi-mi:CCL5(display_short)|uniprotkb:D17S136E(gene name synonym)|uniprotkb:SCYA5(gene name synonym)|uniprotkb:EoCP(gene name synonym)|uniprotkb:Eosinophil chemotactic cytokine(gene name synonym)|uniprotkb:SIS-delta(gene name synonym)|uniprotkb:Small-inducible cytokine A5(gene name synonym)|uniprotkb:T cell-specific protein P228(gene name synonym)|uniprotkb:T-cell-specific protein RANTES(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873953|imex:IM-13779-8100	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003474(Gluconate transporter)|refseq:WP_002209536.1|go:""GO:0015128""(gluconate transmembrane transporter activity)|go:""GO:0016020""(membrane)|refseq:YP_002348849.1"	"refseq:NP_002976.2|ensembl:ENSG00000271503.7(gene)|ensembl:ENSG00000274233.4(gene)|ensembl:ENST00000605140.6(transcript)|ensembl:ENST00000605509.2(transcript)|ensembl:ENST00000613606.2(transcript)|ensembl:ENST00000618639.4(transcript)|go:""GO:0002407""(dendritic cell chemotaxis)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002676""(regulation of chronic inflammatory response)|go:""GO:0004435""(phosphatidylinositol-4,5-bisphosphate phospholipase C activity)|go:""GO:0004672""(protein kinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006887""(exocytosis)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008009""(chemokine activity)|go:""GO:0009615""(response to virus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010820""(positive regulation of T cell chemotaxis)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0030298""(receptor signaling protein tyrosine kinase activator activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031328""(obsolete positive regulation of cellular biosynthetic process)|go:""GO:0031584""(activation of phospholipase D activity)|go:""GO:0031726""(CCR1 chemokine receptor binding)|go:""GO:0031729""(CCR4 chemokine receptor binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0033634""(positive regulation of cell-cell adhesion mediated by integrin)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035689""(""chemokine (C-C motif) ligand 5 signaling pathway"")|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042379""(chemokine receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046817""(chemokine receptor antagonist activity)|go:""GO:0048020""(CCR chemokine receptor binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0050863""(regulation of T cell activation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:0070234""(positive regulation of T cell apoptotic process)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|go:""GO:0097696""(cell surface receptor signaling pathway via STAT)|go:""GO:0098586""(cellular response to virus)|go:""GO:1904894""(positive regulation of receptor signaling pathway via STAT)|go:""GO:2000110""(negative regulation of macrophage apoptotic process)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000503""(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|mint:P13501|rcsb pdb:1B3A|rcsb pdb:1EQT|rcsb pdb:1HRJ|rcsb pdb:1RTN|rcsb pdb:1RTO|rcsb pdb:1U4L|rcsb pdb:1U4M|rcsb pdb:1U4P|rcsb pdb:1U4R|rcsb pdb:2L9H|rcsb pdb:2VXW|rcsb pdb:5CMD|rcsb pdb:5COY|rcsb pdb:5DNF|rcsb pdb:5L2U|rcsb pdb:5UIW|rcsb pdb:6AEZ|rcsb pdb:6C6D|rcsb pdb:6FGP|rcsb pdb:6LOG|rcsb pdb:6STK|rcsb pdb:7F1R|rcsb pdb:7O7F|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|dip:DIP-31N|panther:PTHR12015(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:II0t1Tc6ziV59KfG3br4G58qfsU632	rogid:ax9zuZGIpTIg8FnZi3cyCG+C+kQ9606	intact-crc:03CC7F59AEE4BCB0|rigid:bu7B1l6qyzuHqWC3J1Q6JGdzoEE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZED8	uniprotkb:P13236	intact:EBI-2840186|uniprotkb:Q0WET1	intact:EBI-2873970|uniprotkb:P22617|uniprotkb:Q6FGI8|uniprotkb:Q3SXL8|uniprotkb:Q13704|ensembl:ENSP00000478708.1|ensembl:ENSP00000480345.1|ensembl:ENSP00000482259.1	psi-mi:rnb_yerpe(display_long)|uniprotkb:rnb(gene name)|psi-mi:rnb(display_short)|uniprotkb:Exoribonuclease II(gene name synonym)|uniprotkb:YPO2235(locus name)|uniprotkb:y2077(locus name)|uniprotkb:YP_2034(locus name)	"psi-mi:ccl4_human(display_long)|uniprotkb:CCL4(gene name)|psi-mi:CCL4(display_short)|uniprotkb:LAG1(gene name synonym)|uniprotkb:MIP1B(gene name synonym)|uniprotkb:SCYA4(gene name synonym)|uniprotkb:G-26 T-lymphocyte-secreted protein(gene name synonym)|uniprotkb:HC21(gene name synonym)|uniprotkb:Lymphocyte activation gene 1 protein(gene name synonym)|uniprotkb:""MIP-1-beta(1-69)""(gene name synonym)|uniprotkb:Macrophage inflammatory protein 1-beta(gene name synonym)|uniprotkb:PAT 744(gene name synonym)|uniprotkb:Protein H400(gene name synonym)|uniprotkb:SIS-gamma(gene name synonym)|uniprotkb:Small-inducible cytokine A4(gene name synonym)|uniprotkb:T-cell activation protein 2(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873967|imex:IM-13779-8103	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR022966|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011804(Ribonuclease II, bacterial)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008859""(exoribonuclease II activity)|refseq:WP_002210605.1|interpro:IPR001900(Ribonuclease II and R)|refseq:YP_002347207.1|interpro:IPR050180|panther:PTHR23355(orthology-group)"	"refseq:NP_002975.1|refseq:NP_996890.1|dip:DIP-5840N|ensembl:ENSG00000275302.2(gene)|ensembl:ENSG00000275824.4(gene)|ensembl:ENSG00000277943.4(gene)|ensembl:ENST00000615863.2(transcript)|ensembl:ENST00000617322.4(transcript)|ensembl:ENST00000621600.4(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008009""(chemokine activity)|go:""GO:0009615""(response to virus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031726""(CCR1 chemokine receptor binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0048020""(CCR chemokine receptor binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:2000503""(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|mint:P13236|rcsb pdb:1HUM|rcsb pdb:1HUN|rcsb pdb:1JE4|rcsb pdb:2FFK|rcsb pdb:2FIN|rcsb pdb:2X6L|rcsb pdb:3TN2|rcsb pdb:4RAL|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|panther:PTHR12015(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8bPsungEsr2YreZsZg9IgHPm9uI632	rogid:EfoA+ek4mVlaReV80wgU824brpw9606	intact-crc:6F985AA449AEF4E5|rigid:qeVzKTks43IpocEma9QTVwuuJoY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13501	uniprotkb:Q8CZY0	intact:EBI-2848366|uniprotkb:Q0QVW8|uniprotkb:O43646|uniprotkb:Q9NYA2|uniprotkb:Q9UBG2|uniprotkb:Q9UC99|uniprotkb:Q4ZGJ1|ensembl:ENSP00000474141.2|ensembl:ENSP00000475057.1|ensembl:ENSP00000479894.1|ensembl:ENSP00000484921.2	intact:EBI-2843763	psi-mi:ccl5_human(display_long)|uniprotkb:CCL5(gene name)|psi-mi:CCL5(display_short)|uniprotkb:D17S136E(gene name synonym)|uniprotkb:SCYA5(gene name synonym)|uniprotkb:EoCP(gene name synonym)|uniprotkb:Eosinophil chemotactic cytokine(gene name synonym)|uniprotkb:SIS-delta(gene name synonym)|uniprotkb:Small-inducible cytokine A5(gene name synonym)|uniprotkb:T cell-specific protein P228(gene name synonym)|uniprotkb:T-cell-specific protein RANTES(gene name synonym)	psi-mi:q8czy0_yerpe(display_long)|uniprotkb:y3182(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873939|imex:IM-13779-8099	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002976.2|ensembl:ENSG00000271503.7(gene)|ensembl:ENSG00000274233.4(gene)|ensembl:ENST00000605140.6(transcript)|ensembl:ENST00000605509.2(transcript)|ensembl:ENST00000613606.2(transcript)|ensembl:ENST00000618639.4(transcript)|go:""GO:0002407""(dendritic cell chemotaxis)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002676""(regulation of chronic inflammatory response)|go:""GO:0004435""(phosphatidylinositol-4,5-bisphosphate phospholipase C activity)|go:""GO:0004672""(protein kinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006887""(exocytosis)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008009""(chemokine activity)|go:""GO:0009615""(response to virus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010820""(positive regulation of T cell chemotaxis)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0030298""(receptor signaling protein tyrosine kinase activator activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031328""(obsolete positive regulation of cellular biosynthetic process)|go:""GO:0031584""(activation of phospholipase D activity)|go:""GO:0031726""(CCR1 chemokine receptor binding)|go:""GO:0031729""(CCR4 chemokine receptor binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0033634""(positive regulation of cell-cell adhesion mediated by integrin)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035689""(""chemokine (C-C motif) ligand 5 signaling pathway"")|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042379""(chemokine receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046817""(chemokine receptor antagonist activity)|go:""GO:0048020""(CCR chemokine receptor binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0050863""(regulation of T cell activation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:0070234""(positive regulation of T cell apoptotic process)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|go:""GO:0097696""(cell surface receptor signaling pathway via STAT)|go:""GO:0098586""(cellular response to virus)|go:""GO:1904894""(positive regulation of receptor signaling pathway via STAT)|go:""GO:2000110""(negative regulation of macrophage apoptotic process)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000503""(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|mint:P13501|rcsb pdb:1B3A|rcsb pdb:1EQT|rcsb pdb:1HRJ|rcsb pdb:1RTN|rcsb pdb:1RTO|rcsb pdb:1U4L|rcsb pdb:1U4M|rcsb pdb:1U4P|rcsb pdb:1U4R|rcsb pdb:2L9H|rcsb pdb:2VXW|rcsb pdb:5CMD|rcsb pdb:5COY|rcsb pdb:5DNF|rcsb pdb:5L2U|rcsb pdb:5UIW|rcsb pdb:6AEZ|rcsb pdb:6C6D|rcsb pdb:6FGP|rcsb pdb:6LOG|rcsb pdb:6STK|rcsb pdb:7F1R|rcsb pdb:7O7F|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|dip:DIP-31N|panther:PTHR12015(orthology-group)"	"interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR041954|interpro:IPR050612"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ax9zuZGIpTIg8FnZi3cyCG+C+kQ9606	rogid:Y5d3heMPjpe23bUutQ9OKW+v73g632	intact-crc:7EFFCD8B52489926|rigid:eOwyy39oGA4v00oHxxbOgx/n76c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:P13501	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-2848366|uniprotkb:Q0QVW8|uniprotkb:O43646|uniprotkb:Q9NYA2|uniprotkb:Q9UBG2|uniprotkb:Q9UC99|uniprotkb:Q4ZGJ1|ensembl:ENSP00000474141.2|ensembl:ENSP00000475057.1|ensembl:ENSP00000479894.1|ensembl:ENSP00000484921.2	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:ccl5_human(display_long)|uniprotkb:CCL5(gene name)|psi-mi:CCL5(display_short)|uniprotkb:D17S136E(gene name synonym)|uniprotkb:SCYA5(gene name synonym)|uniprotkb:EoCP(gene name synonym)|uniprotkb:Eosinophil chemotactic cytokine(gene name synonym)|uniprotkb:SIS-delta(gene name synonym)|uniprotkb:Small-inducible cytokine A5(gene name synonym)|uniprotkb:T cell-specific protein P228(gene name synonym)|uniprotkb:T-cell-specific protein RANTES(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873960|imex:IM-13779-8101	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:NP_002976.2|ensembl:ENSG00000271503.7(gene)|ensembl:ENSG00000274233.4(gene)|ensembl:ENST00000605140.6(transcript)|ensembl:ENST00000605509.2(transcript)|ensembl:ENST00000613606.2(transcript)|ensembl:ENST00000618639.4(transcript)|go:""GO:0002407""(dendritic cell chemotaxis)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002676""(regulation of chronic inflammatory response)|go:""GO:0004435""(phosphatidylinositol-4,5-bisphosphate phospholipase C activity)|go:""GO:0004672""(protein kinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006887""(exocytosis)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008009""(chemokine activity)|go:""GO:0009615""(response to virus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010820""(positive regulation of T cell chemotaxis)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0030298""(receptor signaling protein tyrosine kinase activator activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031328""(obsolete positive regulation of cellular biosynthetic process)|go:""GO:0031584""(activation of phospholipase D activity)|go:""GO:0031726""(CCR1 chemokine receptor binding)|go:""GO:0031729""(CCR4 chemokine receptor binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0033634""(positive regulation of cell-cell adhesion mediated by integrin)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035689""(""chemokine (C-C motif) ligand 5 signaling pathway"")|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042379""(chemokine receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046817""(chemokine receptor antagonist activity)|go:""GO:0048020""(CCR chemokine receptor binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0050863""(regulation of T cell activation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:0070234""(positive regulation of T cell apoptotic process)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|go:""GO:0097696""(cell surface receptor signaling pathway via STAT)|go:""GO:0098586""(cellular response to virus)|go:""GO:1904894""(positive regulation of receptor signaling pathway via STAT)|go:""GO:2000110""(negative regulation of macrophage apoptotic process)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000503""(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|mint:P13501|rcsb pdb:1B3A|rcsb pdb:1EQT|rcsb pdb:1HRJ|rcsb pdb:1RTN|rcsb pdb:1RTO|rcsb pdb:1U4L|rcsb pdb:1U4M|rcsb pdb:1U4P|rcsb pdb:1U4R|rcsb pdb:2L9H|rcsb pdb:2VXW|rcsb pdb:5CMD|rcsb pdb:5COY|rcsb pdb:5DNF|rcsb pdb:5L2U|rcsb pdb:5UIW|rcsb pdb:6AEZ|rcsb pdb:6C6D|rcsb pdb:6FGP|rcsb pdb:6LOG|rcsb pdb:6STK|rcsb pdb:7F1R|rcsb pdb:7O7F|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|dip:DIP-31N|panther:PTHR12015(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:ax9zuZGIpTIg8FnZi3cyCG+C+kQ9606	intact-crc:64084B908DAB9D44|rigid:KOLd2SOCSj/vH3VQtVhV1S6jfxw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13501	uniprotkb:A0A0H2W1E9	intact:EBI-2848366|uniprotkb:Q0QVW8|uniprotkb:O43646|uniprotkb:Q9NYA2|uniprotkb:Q9UBG2|uniprotkb:Q9UC99|uniprotkb:Q4ZGJ1|ensembl:ENSP00000474141.2|ensembl:ENSP00000475057.1|ensembl:ENSP00000479894.1|ensembl:ENSP00000484921.2	intact:EBI-2843682|uniprotkb:Q74XR1|uniprotkb:Q0WBU8|uniprotkb:Q7CKC3|uniprotkb:A0A2U2H0M0|uniprotkb:A0A384LN63	psi-mi:ccl5_human(display_long)|uniprotkb:CCL5(gene name)|psi-mi:CCL5(display_short)|uniprotkb:D17S136E(gene name synonym)|uniprotkb:SCYA5(gene name synonym)|uniprotkb:EoCP(gene name synonym)|uniprotkb:Eosinophil chemotactic cytokine(gene name synonym)|uniprotkb:SIS-delta(gene name synonym)|uniprotkb:Small-inducible cytokine A5(gene name synonym)|uniprotkb:T cell-specific protein P228(gene name synonym)|uniprotkb:T-cell-specific protein RANTES(gene name synonym)	psi-mi:a0a0h2w1e9_yerpe(display_long)|uniprotkb:arsF(gene name synonym)|uniprotkb:arsB(gene name)|psi-mi:arsB(display_short)|uniprotkb:YPO3347(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873946|imex:IM-13779-8102	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002976.2|ensembl:ENSG00000271503.7(gene)|ensembl:ENSG00000274233.4(gene)|ensembl:ENST00000605140.6(transcript)|ensembl:ENST00000605509.2(transcript)|ensembl:ENST00000613606.2(transcript)|ensembl:ENST00000618639.4(transcript)|go:""GO:0002407""(dendritic cell chemotaxis)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0002676""(regulation of chronic inflammatory response)|go:""GO:0004435""(phosphatidylinositol-4,5-bisphosphate phospholipase C activity)|go:""GO:0004672""(protein kinase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006887""(exocytosis)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008009""(chemokine activity)|go:""GO:0009615""(response to virus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010759""(positive regulation of macrophage chemotaxis)|go:""GO:0010820""(positive regulation of T cell chemotaxis)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0030298""(receptor signaling protein tyrosine kinase activator activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031328""(obsolete positive regulation of cellular biosynthetic process)|go:""GO:0031584""(activation of phospholipase D activity)|go:""GO:0031726""(CCR1 chemokine receptor binding)|go:""GO:0031729""(CCR4 chemokine receptor binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0033634""(positive regulation of cell-cell adhesion mediated by integrin)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035689""(""chemokine (C-C motif) ligand 5 signaling pathway"")|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042119""(neutrophil activation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042379""(chemokine receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045744""(negative regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046817""(chemokine receptor antagonist activity)|go:""GO:0048020""(CCR chemokine receptor binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0050863""(regulation of T cell activation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:0070234""(positive regulation of T cell apoptotic process)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|go:""GO:0097696""(cell surface receptor signaling pathway via STAT)|go:""GO:0098586""(cellular response to virus)|go:""GO:1904894""(positive regulation of receptor signaling pathway via STAT)|go:""GO:2000110""(negative regulation of macrophage apoptotic process)|go:""GO:2000406""(positive regulation of T cell migration)|go:""GO:2000503""(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|mint:P13501|rcsb pdb:1B3A|rcsb pdb:1EQT|rcsb pdb:1HRJ|rcsb pdb:1RTN|rcsb pdb:1RTO|rcsb pdb:1U4L|rcsb pdb:1U4M|rcsb pdb:1U4P|rcsb pdb:1U4R|rcsb pdb:2L9H|rcsb pdb:2VXW|rcsb pdb:5CMD|rcsb pdb:5COY|rcsb pdb:5DNF|rcsb pdb:5L2U|rcsb pdb:5UIW|rcsb pdb:6AEZ|rcsb pdb:6C6D|rcsb pdb:6FGP|rcsb pdb:6LOG|rcsb pdb:6STK|rcsb pdb:7F1R|rcsb pdb:7O7F|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|dip:DIP-31N|panther:PTHR12015(orthology-group)"	"interpro:IPR000802(Arsenical pump membrane protein)|refseq:WP_002209408.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015105""(arsenite transmembrane transporter activity)|go:""GO:0046685""(response to arsenic-containing substance)|refseq:YP_002348240.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ax9zuZGIpTIg8FnZi3cyCG+C+kQ9606	rogid:29UkgoGwdcD64QszTN4O37NX/m8632	intact-crc:5BF348CE2C91F4A8|rigid:OFogEhArtKzamCtTbgZ+v/mtU4c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CLB2	uniprotkb:Q16627	intact:EBI-2866604|uniprotkb:Q74YB0	intact:EBI-1046947|uniprotkb:Q13954|uniprotkb:E1P649|uniprotkb:E1P650|ensembl:ENSP00000481023.1|ensembl:ENSP00000487948.1	"psi-mi:ligb_yerpe(display_long)|uniprotkb:ligB(gene name)|psi-mi:ligB(display_short)|uniprotkb:""Polydeoxyribonucleotide synthase [NAD(+)] B""(gene name synonym)|uniprotkb:YPO0041(locus name)|uniprotkb:YP_0042(locus name)|uniprotkb:y0100(locus name)"	"psi-mi:ccl14_human(display_long)|uniprotkb:Small-inducible cytokine A14(gene name synonym)|uniprotkb:Chemokine CC-1/CC-3(gene name synonym)|uniprotkb:""HCC-1(1-74)""(gene name synonym)|uniprotkb:NCC-2(gene name synonym)|uniprotkb:CCL14(gene name)|psi-mi:CCL14(display_short)|uniprotkb:NCC2(gene name synonym)|uniprotkb:SCYA14(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873989|imex:IM-13779-8104	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020923|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|refseq:WP_002215674.1|interpro:IPR050326|go:""GO:0003911""(""DNA ligase (NAD+) activity"")|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|refseq:YP_002345137.1|panther:PTHR47810(orthology-group)"	"refseq:NP_116738.1|refseq:NP_116739.1|ensembl:ENSG00000276409.5(gene)|ensembl:ENSG00000277236.4(gene)|ensembl:ENST00000618404.5(transcript)|ensembl:ENST00000632700.1(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006954""(inflammatory response)|go:""GO:0008009""(chemokine activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0048020""(CCR chemokine receptor binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070098""(chemokine-mediated signaling pathway)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:2Q8R|rcsb pdb:2Q8T|dip:DIP-5861N|panther:PTHR12015(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GeGJmGHRIDTZu+RtlycljsNaaow632	rogid:wG5eG1+jHjl+XeXCzSQGVhyJqRA9606	intact-crc:D6399AB5A360088B|rigid:iyl/elWT+4dJxkCv5sflFBfOD2Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13236	uniprotkb:Q8ZA76	intact:EBI-2873970|uniprotkb:P22617|uniprotkb:Q6FGI8|uniprotkb:Q3SXL8|uniprotkb:Q13704|ensembl:ENSP00000478708.1|ensembl:ENSP00000480345.1|ensembl:ENSP00000482259.1	intact:EBI-2846943|uniprotkb:Q0WA76	"psi-mi:ccl4_human(display_long)|uniprotkb:CCL4(gene name)|psi-mi:CCL4(display_short)|uniprotkb:LAG1(gene name synonym)|uniprotkb:MIP1B(gene name synonym)|uniprotkb:SCYA4(gene name synonym)|uniprotkb:G-26 T-lymphocyte-secreted protein(gene name synonym)|uniprotkb:HC21(gene name synonym)|uniprotkb:Lymphocyte activation gene 1 protein(gene name synonym)|uniprotkb:""MIP-1-beta(1-69)""(gene name synonym)|uniprotkb:Macrophage inflammatory protein 1-beta(gene name synonym)|uniprotkb:PAT 744(gene name synonym)|uniprotkb:Protein H400(gene name synonym)|uniprotkb:SIS-gamma(gene name synonym)|uniprotkb:Small-inducible cytokine A4(gene name synonym)|uniprotkb:T-cell activation protein 2(gene name synonym)"	psi-mi:glgx_yerpe(display_long)|uniprotkb:glgX(gene name)|psi-mi:glgX(display_short)|uniprotkb:Limit dextrin alpha-1,6-maltotetraose-hydrolase(gene name synonym)|uniprotkb:YPO3941(locus name)|uniprotkb:YP_3303(locus name)|uniprotkb:y3887(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873982|imex:IM-13779-8106	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002975.1|refseq:NP_996890.1|dip:DIP-5840N|ensembl:ENSG00000275302.2(gene)|ensembl:ENSG00000275824.4(gene)|ensembl:ENSG00000277943.4(gene)|ensembl:ENST00000615863.2(transcript)|ensembl:ENST00000617322.4(transcript)|ensembl:ENST00000621600.4(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008009""(chemokine activity)|go:""GO:0009615""(response to virus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031726""(CCR1 chemokine receptor binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0048020""(CCR chemokine receptor binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:2000503""(positive regulation of natural killer cell chemotaxis)|interpro:IPR000827(Small chemokine, C-C group, conserved site)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR036048|interpro:IPR039809|mint:P13236|rcsb pdb:1HUM|rcsb pdb:1HUN|rcsb pdb:1JE4|rcsb pdb:2FFK|rcsb pdb:2FIN|rcsb pdb:2X6L|rcsb pdb:3TN2|rcsb pdb:4RAL|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|panther:PTHR12015(orthology-group)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR022844|interpro:IPR011837(Glycogen debranching enzyme GlgX)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR040784|go:""GO:0004133""(obsolete glycogen debranching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005980""(glycogen catabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_002209499.1|interpro:IPR044505|refseq:YP_002348812.1|panther:PTHR43002(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EfoA+ek4mVlaReV80wgU824brpw9606	rogid:8sHtj0obGqvrIdGE1JWk8okcbRM632	intact-crc:7E2E9EA44A911862|rigid:zOHP5cxY+yHkrhBukkEfe0HqwAo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D194	uniprotkb:A2IDD5	intact:EBI-2847851|uniprotkb:Q74XR4	intact:EBI-2874003|ensembl:ENSP00000293889.6|uniprotkb:Q6ZR33|uniprotkb:Q6T2V5|uniprotkb:Q05CA0|uniprotkb:B4E1U6|uniprotkb:B4DNY4|uniprotkb:Q96S12|uniprotkb:Q8IUR3|uniprotkb:Q05BY7|uniprotkb:Q8NAY7	psi-mi:q8d194_yerpe(display_long)|uniprotkb:dAK1_1(gene name)|psi-mi:dAK1_1(display_short)|uniprotkb:YP_0337(locus name)|uniprotkb:y0840(locus name)	psi-mi:ccd78_human(display_long)|uniprotkb:CCDC78(gene name)|psi-mi:CCDC78(display_short)|uniprotkb:C16orf25(gene name synonym)|uniprotkb:hsCCDC78(gene name synonym)|uniprotkb:JFP10(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874016|imex:IM-13779-8107	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004006(Dak kinase)|go:""GO:0004371""(glycerone kinase activity)|go:""GO:0006071""(glycerol metabolic process)|interpro:IPR050861"	"ensembl:ENSG00000162004.19(gene)|ensembl:ENST00000293889.10(transcript)|go:""GO:0003009""(skeletal muscle contraction)|go:""GO:0005737""(cytoplasm)|go:""GO:0005814""(centriole)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0030030""(cell projection organization)|go:""GO:0042383""(sarcolemma)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0098535""(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:""GO:0098536""(deuterosome)|interpro:IPR029329|interpro:IPR039873|refseq:NP_001026907.2|efo:""Orphanet:319160""|panther:PTHR22106(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PGSwAYXIFUUnJmzpLaHT1vlvQxc632	rogid:w3CrBhREbp+Iuwuta55+oRLZ1tc9606	intact-crc:FF1B2AA79FDD474D|rigid:E9rg10Wjkh85Hc3hY5L2TjzQjyk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3X0	uniprotkb:A0A2S9PH42	intact:EBI-2557532|ensembl:ENSP00000221922.5	intact:EBI-2843976|uniprotkb:Q7CI41|uniprotkb:A0A3N4B635|uniprotkb:Q0WFN6	psi-mi:ccdc9_human(display_long)|uniprotkb:CCDC9(gene name)|psi-mi:CCDC9(display_short)	psi-mi:a0a2s9ph42_yerpe(display_long)|uniprotkb:irp2(gene name)|psi-mi:irp2(display_short)|uniprotkb:YPO1911(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2873996|imex:IM-13779-8105	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056418.1|refseq:XP_016882067.1|ensembl:ENSG00000105321.14(gene)|ensembl:ENST00000221922.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0035145""(exon-exon junction complex)|interpro:IPR029336|mint:Q9Y3X0|panther:PTHR15635(orthology-group)"	"interpro:IPR020806|rcsb pdb:7JTJ|rcsb pdb:7JUA|interpro:IPR029063|interpro:IPR010071(Amino acid adenylation)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001242(Condensation domain)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR020845|go:""GO:0003824""(catalytic activity)|go:""GO:0009403""(toxin biosynthetic process)|go:""GO:0031177""(phosphopantetheine binding)|refseq:WP_002212775.1|rcsb pdb:2N6Y|rcsb pdb:2N6Z|rcsb pdb:5U3H|interpro:IPR023213|interpro:IPR036736|rcsb pdb:7RY6|interpro:IPR042099|refseq:YP_002346902.1|interpro:IPR045851"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ieUMcjasYCi2p57TSacQTDs7nSo9606	rogid:KfeTeZp+lut8Pzz4JrX7HMjjWS0632	intact-crc:9F68F88DE6A144AB|rigid:McLT69xYb73uKopg2JdQmg8wOiQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H2F9	uniprotkb:Q65AQ0	intact:EBI-2813327|uniprotkb:B2R9I3|ensembl:ENSP00000337209.3|ensembl:ENSP00000413406.1|ensembl:ENSP00000466690.1	intact:EBI-2840948|uniprotkb:Q7ARF1|uniprotkb:O68736|uniprotkb:Q74YP7|uniprotkb:A0A1U8QHE0|uniprotkb:A0A384L0B5|uniprotkb:A0A380PGV8	psi-mi:ccd68_human(display_long)|uniprotkb:CCDC68(gene name)|psi-mi:CCDC68(display_short)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se57-1(gene name synonym)	psi-mi:q65aq0_yerpe(display_long)|uniprotkb:YPMT1.20c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874044|imex:IM-13779-8109	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011524500.1|refseq:XP_011524501.1|refseq:XP_011524502.1|refseq:XP_011524503.1|refseq:NP_001137301.1|refseq:NP_079490.1|refseq:XP_006722615.1|ensembl:ENSG00000166510.14(gene)|ensembl:ENST00000337363.8(transcript)|ensembl:ENST00000432185.5(transcript)|ensembl:ENST00000591504.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005814""(centriole)|go:""GO:0008104""(protein localization)|go:""GO:0034454""(microtubule anchoring at centrosome)|go:""GO:0120103""(centriolar subdistal appendage)|interpro:IPR051375|panther:PTHR23171(orthology-group)"	interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|refseq:NP_395356.1|refseq:YP_093897.1|refseq:WP_002211783.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VkiRG+Lu8ZvXSPnAg3+RugJmCco9606	rogid:ddNAMtYP5UYjatxR1iFv4p5Pwns632	intact-crc:C21A9B14A0C0F9FC|rigid:Afd5p83cJlHWIwWcojteZGwntIk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3C0	uniprotkb:A0A0H2W225	intact:EBI-712969|uniprotkb:Q53FF0|uniprotkb:Q6IAI4|uniprotkb:Q96QK0|uniprotkb:B2RC74|ensembl:ENSP00000240079.6	intact:EBI-2844774	psi-mi:wasc3_human(display_long)|uniprotkb:WASHC3(gene name)|psi-mi:WASHC3(display_short)|uniprotkb:Coiled-coil domain-containing protein 53(gene name synonym)|uniprotkb:AD-016(orf name)|uniprotkb:CCDC53(orf name)|uniprotkb:CGI-116(orf name)|uniprotkb:x0009(orf name)	psi-mi:a0a0h2w225_yerpe(display_long)|uniprotkb:sbcC2(gene name)|psi-mi:sbcC2(display_short)|uniprotkb:sbcC(gene name synonym)|uniprotkb:YP_0725(locus name)|uniprotkb:y0976(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874051|imex:IM-13779-8110	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057137.1|ensembl:ENSG00000120860.11(gene)|ensembl:ENST00000240079.11(transcript)|go:""GO:0006887""(exocytosis)|go:""GO:0015031""(protein transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0071203""(WASH complex)|interpro:IPR019309|mint:Q9Y3C0|panther:PTHR13015(orthology-group)"	"interpro:IPR027417|interpro:IPR038729|uniprotkb:A0A6B3T1W4(uniprot-removed-ac)|go:""GO:0004527""(exonuclease activity)|go:""GO:0006302""(double-strand break repair)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002223265.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jonEQJt0wEcrS2YEiKcmmIiZjCA9606	rogid:kLIIS2zCAycudIvZsl7pSdsTqz0632	intact-crc:9E386018A5C66C98|rigid:5tnyEkwLrf/N0d/5Zs+5C2BIAx8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H2F9	uniprotkb:A0A2U2H391	intact:EBI-2813327|uniprotkb:B2R9I3|ensembl:ENSP00000337209.3|ensembl:ENSP00000413406.1|ensembl:ENSP00000466690.1	intact:EBI-2839910|uniprotkb:Q74PZ8|uniprotkb:Q0WJL5|uniprotkb:Q7CG67|uniprotkb:A0A384KPX3|uniprotkb:A0A3N4BBN7	psi-mi:ccd68_human(display_long)|uniprotkb:CCDC68(gene name)|psi-mi:CCDC68(display_short)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se57-1(gene name synonym)	psi-mi:a0a2u2h391_yerpe(display_long)|uniprotkb:YPO0451(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874037|imex:IM-13779-8111	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011524500.1|refseq:XP_011524501.1|refseq:XP_011524502.1|refseq:XP_011524503.1|refseq:NP_001137301.1|refseq:NP_079490.1|refseq:XP_006722615.1|ensembl:ENSG00000166510.14(gene)|ensembl:ENST00000337363.8(transcript)|ensembl:ENST00000432185.5(transcript)|ensembl:ENST00000591504.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005814""(centriole)|go:""GO:0008104""(protein localization)|go:""GO:0034454""(microtubule anchoring at centrosome)|go:""GO:0120103""(centriolar subdistal appendage)|interpro:IPR051375|panther:PTHR23171(orthology-group)"	"interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR023299|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR023298|interpro:IPR018303|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015662""(P-type ion transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR050510|refseq:WP_002209226.1|interpro:IPR036412|interpro:IPR023214|refseq:YP_002345523.1|interpro:IPR044492"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VkiRG+Lu8ZvXSPnAg3+RugJmCco9606	rogid:8b9pkI6hJgu1iWJ1Q5PYQX7cFyg632	intact-crc:8987BE1EE0DE101B|rigid:CGTLdOzJG9mtQq9Xc8XV8zA1JCI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GXB6	uniprotkb:Q9H2F9	intact:EBI-2842443|uniprotkb:Q0WGI3|uniprotkb:Q74TC4|uniprotkb:Q7CJ25|uniprotkb:A0A0H2W4P6|uniprotkb:A0A384KVT4	intact:EBI-2813327|uniprotkb:B2R9I3|ensembl:ENSP00000337209.3|ensembl:ENSP00000413406.1|ensembl:ENSP00000466690.1	psi-mi:a0a2u2gxb6_yerpe(display_long)|uniprotkb:23S rRNA accumulation protein YceD(gene name synonym)|uniprotkb:YPO1594(locus name)	psi-mi:ccd68_human(display_long)|uniprotkb:CCDC68(gene name)|psi-mi:CCDC68(display_short)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se57-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874030|imex:IM-13779-8108	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003772(Protein of unknown function DUF177)|interpro:IPR039255|go:""GO:0042254""(ribosome biogenesis)|refseq:WP_002210930.1|refseq:YP_002346605.1"	"refseq:XP_011524500.1|refseq:XP_011524501.1|refseq:XP_011524502.1|refseq:XP_011524503.1|refseq:NP_001137301.1|refseq:NP_079490.1|refseq:XP_006722615.1|ensembl:ENSG00000166510.14(gene)|ensembl:ENST00000337363.8(transcript)|ensembl:ENST00000432185.5(transcript)|ensembl:ENST00000591504.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005814""(centriole)|go:""GO:0008104""(protein localization)|go:""GO:0034454""(microtubule anchoring at centrosome)|go:""GO:0120103""(centriolar subdistal appendage)|interpro:IPR051375|panther:PTHR23171(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GDUDakEOgj5J/WN78nZbu71zTZY632	rogid:VkiRG+Lu8ZvXSPnAg3+RugJmCco9606	intact-crc:CE618D68C5A3692D|rigid:amViuSuoYLESQYxLuCwQWq8HAoc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H2F9	uniprotkb:P69976	intact:EBI-2813327|uniprotkb:B2R9I3|ensembl:ENSP00000337209.3|ensembl:ENSP00000413406.1|ensembl:ENSP00000466690.1	intact:EBI-2846298|uniprotkb:Q00928|uniprotkb:Q663H8	psi-mi:ccd68_human(display_long)|uniprotkb:CCDC68(gene name)|psi-mi:CCDC68(display_short)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se57-1(gene name synonym)	psi-mi:sctl_yerpe(display_long)|uniprotkb:sctL(gene name)|psi-mi:sctL(display_short)|uniprotkb:Low calcium response locus protein KC(gene name synonym)|uniprotkb:Yop proteins translocation protein L(gene name synonym)|uniprotkb:lcrKC(gene name synonym)|uniprotkb:yscL(gene name synonym)|uniprotkb:YPCD1.61(locus name)|uniprotkb:YP_pCD22(locus name)|uniprotkb:y0020(locus name)|uniprotkb:y5017(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874023|imex:IM-13779-8112	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011524500.1|refseq:XP_011524501.1|refseq:XP_011524502.1|refseq:XP_011524503.1|refseq:NP_001137301.1|refseq:NP_079490.1|refseq:XP_006722615.1|ensembl:ENSG00000166510.14(gene)|ensembl:ENST00000337363.8(transcript)|ensembl:ENST00000432185.5(transcript)|ensembl:ENST00000591504.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005814""(centriole)|go:""GO:0008104""(protein localization)|go:""GO:0034454""(microtubule anchoring at centrosome)|go:""GO:0120103""(centriolar subdistal appendage)|interpro:IPR051375|panther:PTHR23171(orthology-group)"	"interpro:IPR018035|interpro:IPR012842(Type III secretion system HrpE/YscL)|refseq:NP_395195.1|refseq:NP_857721.1|refseq:NP_857916.1|refseq:WP_010981371.1|go:""GO:0005829""(cytosol)|go:""GO:0030254""(protein secretion by the type III secretion system)|mint:P69976|interpro:IPR051472|panther:PTHR34982(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VkiRG+Lu8ZvXSPnAg3+RugJmCco9606	rogid:athJY1P9nVQIKJ7YjlbvP1JJdjU632	intact-crc:FED9A1887C6D1F22|rigid:P4TPWJqSifvBg0v7I61c8JEOZJQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BV29	uniprotkb:A0A2S9PLF9	intact:EBI-2874058|uniprotkb:Q8N788|uniprotkb:Q86TC4|uniprotkb:A8KAL4|uniprotkb:Q8NAR7|ensembl:ENSP00000350695.3|ensembl:ENSP00000397515.2|ensembl:ENSP00000453226.1|ensembl:ENSP00000453607.1	intact:EBI-2841354|uniprotkb:Q74X44|uniprotkb:Q0WBI4|uniprotkb:Q7CKG9|uniprotkb:A0A380PH15	psi-mi:ccd32_human(display_long)|uniprotkb:CCDC32(gene name)|psi-mi:CCDC32(display_short)|uniprotkb:C15orf57(gene name synonym)	psi-mi:a0a2s9plf9_yerpe(display_long)|uniprotkb:phnP(gene name)|psi-mi:phnP(display_short)|uniprotkb:YPO3465(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874066|imex:IM-13779-8113	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000128891.17(gene)|ensembl:ENST00000358005.7(transcript)|ensembl:ENST00000416810.7(transcript)|ensembl:ENST00000559153.5(transcript)|ensembl:ENST00000559291.5(transcript)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0044782""(cilium organization)|go:""GO:0060322""(head development)|go:""GO:2000369""(regulation of clathrin-dependent endocytosis)|interpro:IPR028039|mint:Q9BV29|refseq:NP_001074260.1|refseq:NP_001074261.1|refseq:NP_001276061.1|refseq:NP_443081.1|efo:""Orphanet:528084""|panther:PTHR31800(orthology-group)"	"interpro:IPR001279(Beta-lactamase-like)|interpro:IPR017693(Phosphonate metabolism protein PhnP)|go:""GO:0008081""(phosphoric diester hydrolase activity)|go:""GO:0019700""(organic phosphonate catabolic process)|refseq:WP_002209284.1|refseq:YP_002348354.1|interpro:IPR035682|interpro:IPR036866|interpro:IPR050419"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:14q1XZQbNJwvZwXPIvJXCaGRc/w9606	rogid:inlYtqvN2O/ToeHxbyY8+4PwJr0632	intact-crc:FFD480D23FD63AEA|rigid:EtKRgN0JU/ScBvb50PoYvN0dOj4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CHW4	uniprotkb:Q96LX7	intact:EBI-2848778|uniprotkb:Q74UT0	intact:EBI-719840|uniprotkb:B4DNX7|uniprotkb:B4E1Q5|uniprotkb:A1A4Y7|uniprotkb:Q0P683|uniprotkb:Q5T629|uniprotkb:C9J8L2|ensembl:ENSP00000432172.1|intact:EBI-28984604	psi-mi:purt_yerpe(display_long)|uniprotkb:purT(gene name)|psi-mi:purT(display_short)|uniprotkb:5'-phosphoribosylglycinamide transformylase 2(gene name synonym)|uniprotkb:Formate-dependent GAR transformylase(gene name synonym)|uniprotkb:GAR transformylase 2(gene name synonym)|uniprotkb:Non-folate glycinamide ribonucleotide transformylase(gene name synonym)|uniprotkb:Phosphoribosylglycinamide formyltransferase 2(gene name synonym)|uniprotkb:YPO1775(locus name)|uniprotkb:YP_1618(locus name)|uniprotkb:y2533(locus name)	psi-mi:ccd17_human(display_long)|uniprotkb:CCDC17(gene name)|psi-mi:CCDC17(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874100|imex:IM-13779-8117	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR003135(ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR005862(Phosphoribosylglycinamide formyltransferase 2)|interpro:IPR011054(Rudiment single hybrid motif)|refseq:WP_002211083.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004644""(phosphoribosylglycinamide formyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0043815""(phosphoribosylglycinamide formyltransferase 2 activity)|interpro:IPR048740|interpro:IPR054350|refseq:YP_002346772.1|panther:PTHR43055(orthology-group)"	refseq:NP_001108410.2|refseq:NP_001177111.1|ensembl:ENSG00000159588.15(gene)|ensembl:ENST00000528266.6(transcript)|interpro:IPR038800|panther:PTHR33820(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bCau0DjK5zfXGn3uk1MMfw6Caso632	rogid:Wt6eiQJB7lL9KzWHCXcoFzYTDA09606	intact-crc:A2029168174E48D6|rigid:Xed4CDqWWaR6UxD683nlsksrwrc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5T9S5	uniprotkb:Q8D0R5	intact:EBI-2874090|uniprotkb:Q6ZU17|ensembl:ENSP00000343377.7|ensembl:ENSP00000359299.2	intact:EBI-2850346|uniprotkb:Q74T91	psi-mi:ccd18_human(display_long)|uniprotkb:CCDC18(gene name)|psi-mi:CCDC18(display_short)|uniprotkb:Sarcoma antigen NY-SAR-24(gene name synonym)	psi-mi:q8d0r5_yerpe(display_long)|uniprotkb:cpsG(gene name)|psi-mi:cpsG(display_short)|uniprotkb:y1710(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874087|imex:IM-13779-8115	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001293005.1|refseq:NP_996769.3|ensembl:ENSG00000122483.18(gene)|ensembl:ENST00000343253.11(transcript)|ensembl:ENST00000370276.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0034451""(centriolar satellite)|mint:Q5T9S5|panther:PTHR18875(orthology-group)"	"interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016868""(intramolecular phosphotransferase activity)|interpro:IPR036900"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SppbYnOK+FKJzpWBsZsJJ/coWgI9606	rogid:z2kz1BX3Sd7E73WGqRSF6X0AGrM632	intact-crc:E33F5CF2F1C24AB6|rigid:Q/9qEF7UrXwt6IsTRJ0ExBCkkKY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W4W6	uniprotkb:Q6P2H3	intact:EBI-2843661|uniprotkb:Q74TV2|uniprotkb:Q7CIL3|uniprotkb:A0A2S9PM22|uniprotkb:Q0WEU1	intact:EBI-2808308|uniprotkb:Q5VY68|uniprotkb:Q9H828|uniprotkb:Q9H6Q1|uniprotkb:Q5VY70|uniprotkb:Q9UF52|uniprotkb:D3DPK4|ensembl:ENSP00000252992.4|uniprotkb:B4DRL1|uniprotkb:F8W7K4	psi-mi:a0a0h2w4w6_yerpe(display_long)|uniprotkb:YPO2225(locus name)|uniprotkb:lapB(gene name)|psi-mi:lapB(display_short)	psi-mi:cep85_human(display_long)|uniprotkb:CCDC21(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 21(gene name synonym)|uniprotkb:CEP85(gene name)|psi-mi:CEP85(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874080|imex:IM-13779-8114	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR041166|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_002210615.1|go:""GO:0005506""(iron ion binding)|go:""GO:0008653""(lipopolysaccharide metabolic process)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0046890""(regulation of lipid biosynthetic process)|interpro:IPR030865|refseq:YP_002347197.1|interpro:IPR051012"	"refseq:NP_001306873.1|refseq:NP_073615.2|refseq:NP_001268446.1|refseq:NP_001268447.1|ensembl:ENSG00000130695.16(gene)|ensembl:ENST00000252992.8(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0000922""(spindle pole)|go:""GO:0005730""(nucleolus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007099""(centriole replication)|go:""GO:0016477""(cell migration)|go:""GO:0042802""(identical protein binding)|go:""GO:0046602""(regulation of mitotic centrosome separation)|go:""GO:0098534""(centriole assembly)|interpro:IPR040210|mint:Q6P2H3|rcsb pdb:5OI7|rcsb pdb:5OID|panther:PTHR31075(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7cni0SRWd3fah/tNgRWzUoUBIN8632	rogid:akTkilY7AIoc1FtkiNFwz4oelvI9606	intact-crc:9585D1FD4393F0B9|rigid:IaY9ALn/RoZCgKjhvfw3rgd2ctM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6P2H3	uniprotkb:P69980	intact:EBI-2808308|uniprotkb:Q5VY68|uniprotkb:Q9H828|uniprotkb:Q9H6Q1|uniprotkb:Q5VY70|uniprotkb:Q9UF52|uniprotkb:D3DPK4|ensembl:ENSP00000252992.4|uniprotkb:B4DRL1|uniprotkb:F8W7K4	intact:EBI-2845444|uniprotkb:P42714|uniprotkb:Q663J5|uniprotkb:P40297	psi-mi:cep85_human(display_long)|uniprotkb:CCDC21(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 21(gene name synonym)|uniprotkb:CEP85(gene name)|psi-mi:CEP85(display_short)	psi-mi:yscr_yerpe(display_long)|uniprotkb:yscR(gene name)|psi-mi:yscR(display_short)|uniprotkb:YPCD1.44(locus name)|uniprotkb:y5034(locus name)|uniprotkb:y0037(locus name)|uniprotkb:YP_pCD39(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874073|imex:IM-13779-8116	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001306873.1|refseq:NP_073615.2|refseq:NP_001268446.1|refseq:NP_001268447.1|ensembl:ENSG00000130695.16(gene)|ensembl:ENST00000252992.8(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0000922""(spindle pole)|go:""GO:0005730""(nucleolus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007099""(centriole replication)|go:""GO:0016477""(cell migration)|go:""GO:0042802""(identical protein binding)|go:""GO:0046602""(regulation of mitotic centrosome separation)|go:""GO:0098534""(centriole assembly)|interpro:IPR040210|mint:Q6P2H3|rcsb pdb:5OI7|rcsb pdb:5OID|panther:PTHR31075(orthology-group)"	"refseq:NP_395178.1|refseq:NP_857738.1|refseq:NP_857933.1|interpro:IPR005838(Type III secretion system inner membrane P protein)|interpro:IPR005773(Yop virulence translocation protein R)|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|refseq:WP_002212947.1|panther:PTHR30587(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:akTkilY7AIoc1FtkiNFwz4oelvI9606	rogid:8WQqv7KuV4BZ+uBr2fevGUQFw8E632	intact-crc:9908237A4100FBB5|rigid:wfn/qBIEkIJ9h/ioNIysbtSB93E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96NT0	uniprotkb:Q8ZGE1	intact:EBI-2810325|uniprotkb:Q9BR88|ensembl:ENSP00000259229.2|uniprotkb:B4DJ47	intact:EBI-2852885|uniprotkb:Q0WH55	psi-mi:cc115_human(display_long)|uniprotkb:CCDC115(gene name)|psi-mi:CCDC115(display_short)	psi-mi:hcp_yerpe(display_long)|uniprotkb:hcp(gene name)|psi-mi:hcp(display_short)|uniprotkb:Hybrid-cluster protein(gene name synonym)|uniprotkb:Prismane protein(gene name synonym)|uniprotkb:YPO1360(locus name)|uniprotkb:YP_1235(locus name)|uniprotkb:y2819(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874147|imex:IM-13779-8120	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136710.10(gene)|ensembl:ENST00000259229.7(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0016020""(membrane)|go:""GO:0016471""(vacuolar proton-transporting V-type ATPase complex)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0036295""(cellular response to increased oxygen levels)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0070072""(vacuolar proton-transporting V-type ATPase complex assembly)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR040357|mint:Q96NT0|reactome:R-HSA-8980692|refseq:NP_001308047.1|refseq:NP_001308048.1|refseq:NP_115733.2|efo:""Orphanet:468684""|panther:PTHR31996(orthology-group)"	"interpro:IPR010048(Hybrid cluster protein)|interpro:IPR004137(Prismane)|interpro:IPR011254(Prismane-like)|interpro:IPR016099(Prismane-like, alpha/beta-sandwich)|interpro:IPR016100(Prismane, alpha-bundle)|go:""GO:0004601""(peroxidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0046210""(nitric oxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050418""(hydroxylamine reductase activity)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|refseq:WP_002211359.1|refseq:YP_002346383.1|panther:PTHR30109(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cUCb36pVMieoV7ZwXQPtD/kIAXY9606	rogid:BDSCWHkI35EldQqmZzCxWSEkkTo632	intact-crc:13EE24C0A342B146|rigid:cLP6v78JDg2xEDZ5xr9IjRs6gEE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60293	uniprotkb:Q7ARD3	intact:EBI-746701|ensembl:ENSP00000368017.4|intact:EBI-2874127|uniprotkb:Q6GMU1|uniprotkb:Q6P2S9|uniprotkb:Q6ZV36|uniprotkb:Q96BE7	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:zc3h1_human(display_long)|uniprotkb:Proline/serine-rich coiled-coil protein 2(gene name synonym)|uniprotkb:ZFC3H1(gene name)|psi-mi:ZFC3H1(display_short)|uniprotkb:KIAA0546(gene name synonym)|uniprotkb:PSRC2(gene name synonym)|uniprotkb:CCDC131(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 131(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874124|imex:IM-13779-8121	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000133858.17(gene)|ensembl:ENST00000378743.9(transcript)|go:""GO:0000176""(""nuclear exosome (RNase complex)"")|go:""GO:0000178""(""exosome (RNase complex)"")|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0006396""(RNA processing)|go:""GO:0046872""(metal ion binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019607|interpro:IPR039278|mint:O60293|refseq:NP_659419.3|panther:PTHR21563(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QJlOZNAOi6leWMDpXLZH6hYjMOk9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:21AEBDCF24403CA0|rigid:lobbLc1fzy/bsz5OqCcUt03Fop8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5T0U0	uniprotkb:Q8CZZ7	intact:EBI-2836961|uniprotkb:B2RP70|uniprotkb:Q96MV0|uniprotkb:B7ZMI9|ensembl:ENSP00000407763.2	intact:EBI-2842831|uniprotkb:Q74W48	psi-mi:cc122_human(display_long)|uniprotkb:CCDC122(gene name)|psi-mi:CCDC122(display_short)	psi-mi:q8czz7_yerpe(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:YP_1051(locus name)|uniprotkb:y3075(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874140|imex:IM-13779-8119	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_659411.2|ensembl:ENSG00000151773.13(gene)|ensembl:ENST00000444614.8(transcript)|refseq:XP_016875886.1	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VizjtcFuu/MiF1LTFOlWhEv4O0w9606	rogid:5D57QZRbHjtu2izZZ+54f7spmuk632	intact-crc:1CEED5FB9D3EA632|rigid:BAoPJ6hefZzyK8uP6WEvnvjG03s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5L361	uniprotkb:Q9GZT6	intact:EBI-2874107	intact:EBI-713148|uniprotkb:Q3B781|uniprotkb:Q9GZU6|uniprotkb:A8K8I4|uniprotkb:B4E3L2|ensembl:ENSP00000434724.1|uniprotkb:B3KP87	psi-mi:a0a3g5l361_yerpe(display_long)|uniprotkb:NCTC5923_00760(orf name)|uniprotkb:y0644(locus name)	psi-mi:cc90b_human(display_long)|uniprotkb:CUA003(orf name)|uniprotkb:CCDC90B(gene name)|psi-mi:CCDC90B(display_short)|uniprotkb:MDS011(orf name)|uniprotkb:MDS025(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874110|imex:IM-13779-8122	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A5P8YCB0(uniprot-removed-ac)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR029058|refseq:WP_002210152.1|go:""GO:0006508""(proteolysis)|go:""GO:0008236""(serine-type peptidase activity)"	"refseq:NP_001273045.1|refseq:NP_001273046.1|refseq:NP_001273047.1|refseq:NP_001273048.1|refseq:NP_001273049.1|refseq:NP_068597.2|ensembl:ENSG00000137500.10(gene)|ensembl:ENST00000529689.6(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0031966""(mitochondrial membrane)|interpro:IPR024461|mint:Q9GZT6|rcsb pdb:6H9M|refseq:XP_016873593.1|refseq:XP_005274216.1|panther:PTHR14360(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/vcpLQEm3UcOVBGh9sIuv0SEWGk632	rogid:eFdcuPTHBcuVWQ1tEdAnIKN9IhI9606	intact-crc:F8C07B94C3DD0111|rigid:oosqb1JpQpX1sYRV2qsuVUaTZx0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PKV8	uniprotkb:Q9NV96	intact:EBI-2859198|uniprotkb:Q74WD4|uniprotkb:Q0WHK6|uniprotkb:Q7CH84|uniprotkb:A0A384KBV6	intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|ensembl:ENSP00000230461.6|uniprotkb:E1P539	psi-mi:a0a2s9pkv8_yerpe(display_long)|uniprotkb:YPO1194(locus name)	psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874117|imex:IM-13779-8118	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001763(Rhodanese-like)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|refseq:WP_002210799.1|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0016784""(3-mercaptopyruvate sulfurtransferase activity)|interpro:IPR036873|refseq:YP_002346232.1|interpro:IPR045078|panther:PTHR11364(orthology-group)"	"ensembl:ENSG00000112697.17(gene)|ensembl:ENST00000230461.11(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006855""(xenobiotic transmembrane transport)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0015247""(aminophospholipid flippase activity)|go:""GO:0015917""(aminophospholipid transport)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0045332""(phospholipid translocation)|go:""GO:0061092""(positive regulation of phospholipid translocation)|go:""GO:0070863""(positive regulation of protein exit from endoplasmic reticulum)|go:""GO:1990531""(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7L|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|rcsb pdb:7PY4|rcsb pdb:7VGI|rcsb pdb:7VGJ|rcsb pdb:7VSG|rcsb pdb:7VSH|rcsb pdb:8OX4|rcsb pdb:8OX5|rcsb pdb:8OX6|rcsb pdb:8OX7|rcsb pdb:8OX8|rcsb pdb:8OX9|rcsb pdb:8OXA|rcsb pdb:8OXB|rcsb pdb:8OXC|reactome:R-HSA-6798695|refseq:NP_001137430.1|refseq:NP_060717.1|panther:PTHR10926(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tC9S/oaqk3d0afXfuawLwoksqPQ632	rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606	intact-crc:C6A1CA28CF0A2C2F|rigid:pjdlCdSOuL6cHgmqoAG25mXxtrE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N3R3	uniprotkb:Q74XD3	intact:EBI-2874172|uniprotkb:Q4G0M4|uniprotkb:Q495R1|uniprotkb:A8K9P1|uniprotkb:Q0P5T9|uniprotkb:Q6GMU8|uniprotkb:Q495R3|ensembl:ENSP00000341539.4|ensembl:ENSP00000402581.1	intact:EBI-2855960|uniprotkb:Q8ZIY8|uniprotkb:Q0WJW4|uniprotkb:Q7CKN0	psi-mi:tcaim_human(display_long)|uniprotkb:TCAIM(gene name)|psi-mi:TCAIM(display_short)|uniprotkb:C3orf23(gene name synonym)|uniprotkb:TOAG1(gene name synonym)|uniprotkb:Tolerance associated gene-1 protein(gene name synonym)	psi-mi:cuta_yerpe(display_long)|uniprotkb:cutA(gene name)|psi-mi:cutA(display_short)|uniprotkb:YPO0346(locus name)|uniprotkb:y0604(locus name)|uniprotkb:YP_0500(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874182|imex:IM-13779-8125	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269842.1|refseq:NP_001269843.1|refseq:NP_001269844.1|refseq:NP_001025010.1|refseq:NP_001025011.1|refseq:NP_776187.2|refseq:XP_016861740.1|ensembl:ENSG00000179152.20(gene)|ensembl:ENST00000342649.9(transcript)|ensembl:ENST00000417237.5(transcript)|go:""GO:0005739""(mitochondrion)|interpro:IPR027986|interpro:IPR027989|interpro:IPR028031|rcsb pdb:8I0K|panther:PTHR31596(orthology-group)"	"refseq:WP_002209122.1|interpro:IPR023700|interpro:IPR004323(Divalent ion tolerance protein, CutA1)|interpro:IPR011322(Nitrogen regulatory PII-like, alpha/beta)|rcsb pdb:3GSD|interpro:IPR015867(Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal)|go:""GO:0005507""(copper ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0010038""(response to metal ion)|refseq:YP_002345424.1|panther:PTHR23419(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vDrfRDnbPIJIytD+WmROcrmmDzQ9606	rogid:oZ+dqE3f5QFb+ouShZmMFoGk+4Q632	intact-crc:C700EE7FC489C276|rigid:spPGxVVW+1WN8J4DDPsNatVxBHE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HBI5	uniprotkb:A0A3G5LAS3	intact:EBI-2874199|uniprotkb:B2R9U0|ensembl:ENSP00000232519.5|ensembl:ENSP00000418086.1|ensembl:ENSP00000419977.1|ensembl:ENSP00000438275.1	intact:EBI-2858353|uniprotkb:A0A1U8QWA8|uniprotkb:Q74YJ3|uniprotkb:Q9ZGY3|uniprotkb:Q7ARA8|uniprotkb:A0A0H2W1Z2|uniprotkb:A0A384LAQ1	psi-mi:cep15_human(display_long)|uniprotkb:Centrosomal protein 15 kDa(gene name synonym)|uniprotkb:C3orf14(orf name)|uniprotkb:HT021(orf name)|uniprotkb:CEP15(gene name)|psi-mi:CEP15(display_short)	psi-mi:a0a3g5las3_yerpe(display_long)|uniprotkb:YPMT1.86c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874196|imex:IM-13779-8124	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_065736.1|refseq:NP_001278870.1|refseq:NP_001278871.1|refseq:XP_016862420.1|ensembl:ENSG00000114405.11(gene)|ensembl:ENST00000232519.9(transcript)|ensembl:ENST00000462069.6(transcript)|ensembl:ENST00000494481.5(transcript)|ensembl:ENST00000542214.2(transcript)|go:""GO:0005929""(cilium)|interpro:IPR028006|panther:PTHR14286(orthology-group)"	refseq:NP_395432.1|refseq:WP_002228802.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bV6mfq39OgxyOD9I9BFN6hLNnDk9606	rogid:7tH07Yv4XPfqK+U1ZykbkUm6Uuk632	intact-crc:67BFE59C4523DD5B|rigid:SgKr/FDt4jkctYPHwSpn/Oqo4uw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CGH1	uniprotkb:Q9Y2M2	intact:EBI-2874164|uniprotkb:Q74RP7	intact:EBI-2874154|uniprotkb:B7Z6E3|uniprotkb:F5H2S5|uniprotkb:A6NFA9|uniprotkb:Q7Z7K4|uniprotkb:B3KS84|ensembl:ENSP00000439378.1	psi-mi:y661_yerpe(display_long)|uniprotkb:YPO0661(locus name)|uniprotkb:y3517(locus name)|uniprotkb:YP_2976(locus name)	psi-mi:ssuh2_human(display_long)|uniprotkb:SSUH2(gene name)|psi-mi:SSUH2(display_short)|uniprotkb:Protein ssu-2 homolog(gene name synonym)|uniprotkb:FLS485(orf name)|uniprotkb:C3orf32(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874161|imex:IM-13779-8123	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR009576(Protein of unknown function DUF1190)|refseq:WP_002357252.1|refseq:YP_002345729.1	"ensembl:ENSG00000125046.16(gene)|ensembl:ENST00000544814.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042476""(odontogenesis)|go:""GO:0051082""(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR052789|mint:Q9Y2M2|refseq:NP_001243677.1|refseq:NP_001243678.1|refseq:NP_057015.1|refseq:XP_016862027.1|refseq:XP_016862028.1|refseq:XP_016862029.1|refseq:XP_016862030.1|refseq:XP_016862031.1|efo:""Orphanet:99789""|panther:PTHR48377(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3Rz9xFrnbqvNkeml5DV2NR3SKyI632	rogid:QTureJDO1Mkk761mijaBVCRCS349606	intact-crc:CD8D9DBC112553CA|rigid:D24UmPceLQFdtIYIAVuJ21JLE58	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6NW34	uniprotkb:P68587	intact:EBI-2514392|uniprotkb:Q9H7U0|uniprotkb:Q9UFM4|uniprotkb:Q68DM6|uniprotkb:D3DN69|ensembl:ENSP00000320251.5	intact:EBI-2844901|uniprotkb:P40295	psi-mi:nepro_human(display_long)|uniprotkb:NEPRO(gene name)|psi-mi:NEPRO(display_short)|uniprotkb:C3orf17(gene name synonym)	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874189|imex:IM-13779-8126	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000163608.15(gene)|ensembl:ENST00000314400.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|interpro:IPR027951|interpro:IPR052835|mint:Q6NW34|refseq:NP_001306038.1|refseq:NP_001306039.1|refseq:NP_001306040.1|refseq:NP_001306041.1|refseq:NP_001306043.1|refseq:NP_001306044.1|refseq:NP_056227.2|efo:""Orphanet:93347""|panther:PTHR34761(orthology-group)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:br4UAJBanB0yJJzizE1yXlJqtwQ9606	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	intact-crc:98E586441B1EA677|rigid:sFs5rkzVSJAOGkIuGboGwG6V6eI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5RIA9	uniprotkb:A0A380PJW4	intact:EBI-2874218|uniprotkb:Q8N7U8|ensembl:ENSP00000371842.3	intact:EBI-2847196|uniprotkb:Q0WI94|uniprotkb:Q7CGR6	psi-mi:zng1e_human(display_long)|uniprotkb:ZNG1E(gene name)|psi-mi:ZNG1E(display_short)|uniprotkb:CBWD5(gene name synonym)|uniprotkb:Cobalamin synthase W domain-containing protein 5(gene name synonym)	psi-mi:a0a380pjw4_yerpe(display_long)|uniprotkb:YPO0947(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874215|imex:IM-13779-8130	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001317597.1|ensembl:ENSG00000147996.17(gene)|ensembl:ENST00000382405.8(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|go:""GO:0051604""(protein maturation)|go:""GO:0140827""(zinc chaperone activity)|interpro:IPR003495(""Cobalamin (vitamin B12) biosynthesis CobW-like"")|interpro:IPR011629(""Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal"")|interpro:IPR027417|interpro:IPR036627|interpro:IPR051316|panther:PTHR13748(orthology-group)"	"interpro:IPR020974|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|interpro:IPR028994|refseq:WP_002224905.1|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016740""(transferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR038383|refseq:YP_002345994.1|interpro:IPR049824"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mUGZVNsC2clYBQyb/r21oRd19EQ9606	rogid:3Aj0qy9DiLKc8Bx9KbIJWyE+XAM632	intact-crc:C2F04E037CD9B676|rigid:iymOo4iAsXqVESIJ8IHN60ymFVA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14384	uniprotkb:A0A3N4B6K1	intact:EBI-2561541|uniprotkb:B2R800|uniprotkb:Q9H2K9|ensembl:ENSP00000339157.3|ensembl:ENSP00000447255.1|ensembl:ENSP00000448517.1	intact:EBI-2841967|uniprotkb:Q7CHV2|uniprotkb:Q0WG31	psi-mi:cbpm_human(display_long)|uniprotkb:CPM(gene name)|psi-mi:CPM(display_short)	psi-mi:a0a3n4b6k1_yerpe(display_long)|uniprotkb:EIIAB-Man(gene name synonym)|uniprotkb:gptB(gene name)|psi-mi:gptB(display_short)|uniprotkb:EIII-Man(gene name synonym)|uniprotkb:manX(gene name synonym)|uniprotkb:ptsL(gene name synonym)|uniprotkb:YPO1758(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874227|imex:IM-13779-8128	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001005502.1|refseq:NP_001865.1|refseq:NP_938079.1|ensembl:ENSG00000135678.12(gene)|ensembl:ENST00000338356.7(transcript)|ensembl:ENST00000546373.5(transcript)|ensembl:ENST00000551568.6(transcript)|go:""GO:0004180""(carboxypeptidase activity)|go:""GO:0004181""(metallocarboxypeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006518""(peptide metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0009986""(cell surface)|go:""GO:0016485""(protein processing)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098552""(side of membrane)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR033842|interpro:IPR050753|rcsb pdb:1UWY|reactome:R-HSA-163125|panther:PTHR11532(orthology-group)"	"interpro:IPR004701(Phosphotransferase system, fructose subfamily IIA component)|interpro:IPR013789(Phosphotransferase system, fructose subfamily IIA component, subgroup)|interpro:IPR004720(Phosphotransferase system, sorbose subfamily IIB component)|interpro:IPR018455|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|interpro:IPR033887|interpro:IPR036662|interpro:IPR036667|refseq:WP_002211069.1|refseq:YP_002346757.1|interpro:IPR051471|panther:PTHR33799(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nczGYHxDk+MrUSPPoJM1pyDJYFA9606	rogid:6EMnus36OolbaozHpfdN+4jAtF0632	intact-crc:BE2AE4A8D8353AEE|rigid:PALOJGTc2N+ZasLFUbIyaa6oMXs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B418	uniprotkb:Q92793	intact:EBI-2840046|uniprotkb:Q0WFD2|uniprotkb:Q74U73|uniprotkb:Q7CIA4|uniprotkb:A0A380PD11	intact:EBI-81215|uniprotkb:O00147|uniprotkb:Q16376|ensembl:ENSP00000262367.5|uniprotkb:D3DUC9|uniprotkb:Q4LE28	psi-mi:a0a3n4b418_yerpe(display_long)|uniprotkb:YPO2020(locus name)	psi-mi:cbp_human(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)|uniprotkb:CBP(gene name synonym)|uniprotkb:Histone lysine acetyltransferase CREBBP(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)|uniprotkb:Protein lactyltransferas CREBBP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874241|imex:IM-13779-8131	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_002347006.1|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032698|refseq:WP_002211233.1	"ensembl:ENSG00000005339.15(gene)|ensembl:ENST00000262367.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0000785""(chromatin)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002039""(p53 binding)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0003682""(chromatin binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006473""(protein acetylation)|go:""GO:0007165""(signal transduction)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008589""(regulation of smoothened signaling pathway)|go:""GO:0016407""(acetyltransferase activity)|go:""GO:0016479""(negative regulation of transcription by RNA polymerase I)|go:""GO:0016604""(nuclear body)|go:""GO:0018076""(N-terminal peptidyl-lysine acetylation)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0034212""(protein N-acetyltransferase activity)|go:""GO:0034644""(cellular response to UV)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042592""(homeostatic process)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0043426""(MRF binding)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0048511""(rhythmic process)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061733""(protein-lysine-acetyltransferase activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0120300""(""peptide lactyltransferase (CoA-dependent) activity"")|go:""GO:0120301""(""histone lactyltransferase (CoA-dependent) activity"")|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q92793|rcsb pdb:1JSP|rcsb pdb:1LIQ|rcsb pdb:1RDT|rcsb pdb:1WO3|rcsb pdb:1WO4|rcsb pdb:1WO5|rcsb pdb:1WO6|rcsb pdb:1WO7|rcsb pdb:1ZOQ|rcsb pdb:2D82|rcsb pdb:2KJE|rcsb pdb:2KWF|rcsb pdb:2L84|rcsb pdb:2L85|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2N1A|rcsb pdb:2RNY|rcsb pdb:3DWY|rcsb pdb:3P1C|rcsb pdb:3P1D|rcsb pdb:3P1E|rcsb pdb:3P1F|rcsb pdb:3SVH|rcsb pdb:4A9K|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4NR4|rcsb pdb:4NR5|rcsb pdb:4NR6|rcsb pdb:4NR7|rcsb pdb:4NYV|rcsb pdb:4NYW|rcsb pdb:4NYX|rcsb pdb:4OUF|rcsb pdb:4TQN|rcsb pdb:4TS8|rcsb pdb:4WHU|rcsb pdb:4YK0|rcsb pdb:5CGP|rcsb pdb:5DBM|rcsb pdb:5EIC|rcsb pdb:5ENG|rcsb pdb:5EP7|rcsb pdb:5GH9|rcsb pdb:5H85|rcsb pdb:5I83|rcsb pdb:5I86|rcsb pdb:5I89|rcsb pdb:5I8B|rcsb pdb:5I8G|rcsb pdb:5J0D|rcsb pdb:5JEM|rcsb pdb:5KTU|rcsb pdb:5KTW|rcsb pdb:5KTX|rcsb pdb:5LPJ|rcsb pdb:5LPL|rcsb pdb:5MME|rcsb pdb:5MMG|rcsb pdb:5MPK|rcsb pdb:5MPN|rcsb pdb:5MPZ|rcsb pdb:5MQE|rcsb pdb:5MQG|rcsb pdb:5MQK|rcsb pdb:5NLK|rcsb pdb:5NRW|rcsb pdb:5NU3|rcsb pdb:5OWK|rcsb pdb:5SVH|rcsb pdb:5TB6|rcsb pdb:5W0E|rcsb pdb:5W0F|rcsb pdb:5W0L|rcsb pdb:5W0Q|rcsb pdb:5XXH|rcsb pdb:6ALB|rcsb pdb:6ALC|rcsb pdb:6AXQ|rcsb pdb:6AY3|rcsb pdb:6AY5|rcsb pdb:6DMK|rcsb pdb:6ES5|rcsb pdb:6ES6|rcsb pdb:6ES7|rcsb pdb:6FQO|rcsb pdb:6FQT|rcsb pdb:6FQU|rcsb pdb:6FR0|rcsb pdb:6FRF|rcsb pdb:6LQX|rcsb pdb:6M64|rcsb pdb:6QST|rcsb pdb:6SQE|rcsb pdb:6SQF|rcsb pdb:6SQM|rcsb pdb:6SXX|rcsb pdb:6YIJ|rcsb pdb:6YIK|rcsb pdb:6YIL|rcsb pdb:6YIM|rcsb pdb:7CO1|rcsb pdb:7EVJ|rcsb pdb:7JFL|rcsb pdb:7JFM|rcsb pdb:7JUO|rcsb pdb:7KPY|rcsb pdb:7RLE|rcsb pdb:7TB3|rcsb pdb:7TBH|rcsb pdb:7UGE|rcsb pdb:7UGL|rcsb pdb:7WX2|rcsb pdb:7XH6|rcsb pdb:7XHE|rcsb pdb:7XI0|rcsb pdb:7XIJ|rcsb pdb:7XM7|rcsb pdb:7XNE|rcsb pdb:7XNG|rcsb pdb:8FUP|rcsb pdb:8FV2|rcsb pdb:8FXA|rcsb pdb:8FXE|rcsb pdb:8FXN|rcsb pdb:8FXO|rcsb pdb:8G6T|rcsb pdb:8GA2|rcsb pdb:8HAL|rcsb pdb:8HAM|rcsb pdb:8HAN|rcsb pdb:9J6O|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-6803204|reactome:R-HSA-8866907|reactome:R-HSA-8939246|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9617629|reactome:R-HSA-9705671|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9759194|reactome:R-HSA-9768919|reactome:R-HSA-9793380|reactome:R-HSA-9818026|reactome:R-HSA-9818027|reactome:R-HSA-9818028|reactome:R-HSA-9818030|reactome:R-HSA-9818032|reactome:R-HSA-9818035|reactome:R-HSA-9818749|reactome:R-HSA-9819196|reactome:R-HSA-9833109|reactome:R-HSA-9841922|reactome:R-HSA-9856649|refseq:NP_001073315.1|refseq:NP_004371.2|panther:PTHR13808(orthology-group)|efo:""Orphanet:353277""|efo:""Orphanet:353281""|efo:""Orphanet:370026""|efo:""Orphanet:592574""|dip:DIP-952N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:wzxT1bjS3dgwqWVrMmCge2eTVT0632	rogid:WWX7TFIpcDwoR5f5Sm1eQ6nma1E9606	intact-crc:28E1496EADE6B947|rigid:C5HhiwF7lI2O/ZTzONRz8J8Ntsk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VCW6	uniprotkb:Q9Y3M2	intact:EBI-2846132	intact:EBI-947308|uniprotkb:Q66GT6|uniprotkb:Q9UIK9|uniprotkb:B2R4S2|ensembl:ENSP00000216029.3|ensembl:ENSP00000380026.2|ensembl:ENSP00000412260.2|ensembl:ENSP00000413934.2	psi-mi:a0a6b3vcw6_yerpe(display_long)|uniprotkb:YP_3785(locus name)|uniprotkb:y3786(locus name)|uniprotkb:sbcC3(gene name)|psi-mi:sbcC3(display_short)	psi-mi:cby1_human(display_long)|uniprotkb:CBY1(gene name)|psi-mi:CBY1(display_short)|uniprotkb:C22orf2(gene name synonym)|uniprotkb:CBY(gene name synonym)|uniprotkb:HRIHFB2025(orf name)|uniprotkb:ARB1(gene name synonym)|uniprotkb:PGEA1(gene name synonym)|uniprotkb:PKD2 interactor, Golgi and endoplasmic reticulum-associated 1(gene name synonym)|uniprotkb:PIGEA-14(gene name synonym)|uniprotkb:Cytosolic leucine-rich protein(gene name synonym)|uniprotkb:ARPP-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874208|imex:IM-13779-8127	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q8CKB6(uniprot-removed-ac)|refseq:WP_002209173.1|interpro:IPR027417	"ensembl:ENSG00000100211.12(gene)|ensembl:ENST00000216029.8(transcript)|ensembl:ENST00000396811.6(transcript)|ensembl:ENST00000411557.6(transcript)|ensembl:ENST00000416285.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008104""(protein localization)|go:""GO:0016607""(nuclear speck)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0033504""(floor plate development)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060271""(cilium assembly)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|interpro:IPR028118|mint:Q9Y3M2|rcsb pdb:4WRQ|reactome:R-HSA-3769402|refseq:NP_001002880.2|refseq:NP_056188.1|dip:DIP-29651N|efo:""Orphanet:475""|panther:PTHR21533(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JAJQ2/SqTxwkVfzJ9zXmGfJ8osk632	rogid:RqvyVBe3nAEf0bYnToiVsM5hLhc9606	intact-crc:9BA113E9E203FB39|rigid:e+xtENhYLYQ0ledPJhDvRo2WNIc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92793	uniprotkb:A0A2S9PBR0	intact:EBI-81215|uniprotkb:O00147|uniprotkb:Q16376|ensembl:ENSP00000262367.5|uniprotkb:D3DUC9|uniprotkb:Q4LE28	intact:EBI-2860272|uniprotkb:Q7CIN4|uniprotkb:Q0WEY3	psi-mi:cbp_human(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)|uniprotkb:CBP(gene name synonym)|uniprotkb:Histone lysine acetyltransferase CREBBP(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)|uniprotkb:Protein lactyltransferas CREBBP(gene name synonym)	psi-mi:a0a2s9pbr0_yerpe(display_long)|uniprotkb:oppA(gene name)|psi-mi:oppA(display_short)|uniprotkb:YPO2182(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874234|imex:IM-13779-8129	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000005339.15(gene)|ensembl:ENST00000262367.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0000785""(chromatin)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002039""(p53 binding)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0003682""(chromatin binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006473""(protein acetylation)|go:""GO:0007165""(signal transduction)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008589""(regulation of smoothened signaling pathway)|go:""GO:0016407""(acetyltransferase activity)|go:""GO:0016479""(negative regulation of transcription by RNA polymerase I)|go:""GO:0016604""(nuclear body)|go:""GO:0018076""(N-terminal peptidyl-lysine acetylation)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0034212""(protein N-acetyltransferase activity)|go:""GO:0034644""(cellular response to UV)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042592""(homeostatic process)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0043426""(MRF binding)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0048511""(rhythmic process)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061733""(protein-lysine-acetyltransferase activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0120300""(""peptide lactyltransferase (CoA-dependent) activity"")|go:""GO:0120301""(""histone lactyltransferase (CoA-dependent) activity"")|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q92793|rcsb pdb:1JSP|rcsb pdb:1LIQ|rcsb pdb:1RDT|rcsb pdb:1WO3|rcsb pdb:1WO4|rcsb pdb:1WO5|rcsb pdb:1WO6|rcsb pdb:1WO7|rcsb pdb:1ZOQ|rcsb pdb:2D82|rcsb pdb:2KJE|rcsb pdb:2KWF|rcsb pdb:2L84|rcsb pdb:2L85|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2N1A|rcsb pdb:2RNY|rcsb pdb:3DWY|rcsb pdb:3P1C|rcsb pdb:3P1D|rcsb pdb:3P1E|rcsb pdb:3P1F|rcsb pdb:3SVH|rcsb pdb:4A9K|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4NR4|rcsb pdb:4NR5|rcsb pdb:4NR6|rcsb pdb:4NR7|rcsb pdb:4NYV|rcsb pdb:4NYW|rcsb pdb:4NYX|rcsb pdb:4OUF|rcsb pdb:4TQN|rcsb pdb:4TS8|rcsb pdb:4WHU|rcsb pdb:4YK0|rcsb pdb:5CGP|rcsb pdb:5DBM|rcsb pdb:5EIC|rcsb pdb:5ENG|rcsb pdb:5EP7|rcsb pdb:5GH9|rcsb pdb:5H85|rcsb pdb:5I83|rcsb pdb:5I86|rcsb pdb:5I89|rcsb pdb:5I8B|rcsb pdb:5I8G|rcsb pdb:5J0D|rcsb pdb:5JEM|rcsb pdb:5KTU|rcsb pdb:5KTW|rcsb pdb:5KTX|rcsb pdb:5LPJ|rcsb pdb:5LPL|rcsb pdb:5MME|rcsb pdb:5MMG|rcsb pdb:5MPK|rcsb pdb:5MPN|rcsb pdb:5MPZ|rcsb pdb:5MQE|rcsb pdb:5MQG|rcsb pdb:5MQK|rcsb pdb:5NLK|rcsb pdb:5NRW|rcsb pdb:5NU3|rcsb pdb:5OWK|rcsb pdb:5SVH|rcsb pdb:5TB6|rcsb pdb:5W0E|rcsb pdb:5W0F|rcsb pdb:5W0L|rcsb pdb:5W0Q|rcsb pdb:5XXH|rcsb pdb:6ALB|rcsb pdb:6ALC|rcsb pdb:6AXQ|rcsb pdb:6AY3|rcsb pdb:6AY5|rcsb pdb:6DMK|rcsb pdb:6ES5|rcsb pdb:6ES6|rcsb pdb:6ES7|rcsb pdb:6FQO|rcsb pdb:6FQT|rcsb pdb:6FQU|rcsb pdb:6FR0|rcsb pdb:6FRF|rcsb pdb:6LQX|rcsb pdb:6M64|rcsb pdb:6QST|rcsb pdb:6SQE|rcsb pdb:6SQF|rcsb pdb:6SQM|rcsb pdb:6SXX|rcsb pdb:6YIJ|rcsb pdb:6YIK|rcsb pdb:6YIL|rcsb pdb:6YIM|rcsb pdb:7CO1|rcsb pdb:7EVJ|rcsb pdb:7JFL|rcsb pdb:7JFM|rcsb pdb:7JUO|rcsb pdb:7KPY|rcsb pdb:7RLE|rcsb pdb:7TB3|rcsb pdb:7TBH|rcsb pdb:7UGE|rcsb pdb:7UGL|rcsb pdb:7WX2|rcsb pdb:7XH6|rcsb pdb:7XHE|rcsb pdb:7XI0|rcsb pdb:7XIJ|rcsb pdb:7XM7|rcsb pdb:7XNE|rcsb pdb:7XNG|rcsb pdb:8FUP|rcsb pdb:8FV2|rcsb pdb:8FXA|rcsb pdb:8FXE|rcsb pdb:8FXN|rcsb pdb:8FXO|rcsb pdb:8G6T|rcsb pdb:8GA2|rcsb pdb:8HAL|rcsb pdb:8HAM|rcsb pdb:8HAN|rcsb pdb:9J6O|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-6803204|reactome:R-HSA-8866907|reactome:R-HSA-8939246|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9617629|reactome:R-HSA-9705671|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9759194|reactome:R-HSA-9768919|reactome:R-HSA-9793380|reactome:R-HSA-9818026|reactome:R-HSA-9818027|reactome:R-HSA-9818028|reactome:R-HSA-9818030|reactome:R-HSA-9818032|reactome:R-HSA-9818035|reactome:R-HSA-9818749|reactome:R-HSA-9819196|reactome:R-HSA-9833109|reactome:R-HSA-9841922|reactome:R-HSA-9856649|refseq:NP_001073315.1|refseq:NP_004371.2|panther:PTHR13808(orthology-group)|efo:""Orphanet:353277""|efo:""Orphanet:353281""|efo:""Orphanet:370026""|efo:""Orphanet:592574""|dip:DIP-952N"	"interpro:IPR000914(Bacterial extracellular solute-binding protein, family 5)|interpro:IPR039424|interpro:IPR023765|refseq:WP_002218177.1|interpro:IPR030678|go:""GO:0015833""(peptide transport)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|go:""GO:1904680""(peptide transmembrane transporter activity)|refseq:YP_002347155.1|panther:PTHR30290(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:WWX7TFIpcDwoR5f5Sm1eQ6nma1E9606	rogid:pn2AAG+/dGH62sfV+r9JinIZHfc632	intact-crc:48989EC87CF7E3B7|rigid:TeUx87/PfMyJkxWebEanIH7iErg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P47755	uniprotkb:Q8ZHK5	intact:EBI-762451|ensembl:ENSP00000354947.2|uniprotkb:B4DG50	intact:EBI-2840092|uniprotkb:Q0WIF2	psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short)	psi-mi:syk_yerpe(display_long)|uniprotkb:lysS(gene name)|psi-mi:lysS(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO0888(locus name)|uniprotkb:YP_3584(locus name)|uniprotkb:y3272(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874255|imex:IM-13779-8132	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006127.1|ensembl:ENSG00000198898.16(gene)|ensembl:ENST00000361183.8(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|panther:PTHR10653(orthology-group)"	"interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR044136|go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|refseq:WP_002209930.1|interpro:IPR034762|refseq:YP_002345936.1|interpro:IPR045864|panther:PTHR42918(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606	rogid:7RLsEIl+oAzL6AY+mxY4y8mj2AM632	intact-crc:41ACE1926429A10B|rigid:c63dOrlerlngPAUu3ZtVFmrKFek	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q03135	uniprotkb:Q7CL81	intact:EBI-603614|uniprotkb:Q9UGP1|uniprotkb:Q9UNG1|uniprotkb:Q9UQH6|ensembl:ENSP00000339191.2	intact:EBI-2852239|uniprotkb:Q74PP8	psi-mi:cav1_human(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)	psi-mi:q7cl81_yerpe(display_long)|uniprotkb:treB(gene name)|psi-mi:treB(display_short)|uniprotkb:YPO3697(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874269|imex:IM-13779-8135	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105974.13(gene)|ensembl:ENST00000341049.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001525""(angiogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0001960""(negative regulation of cytokine-mediated signaling pathway)|go:""GO:0002067""(glandular epithelial cell differentiation)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0002095""(caveolar macromolecular signaling complex)|go:""GO:0002931""(response to ischemia)|go:""GO:0003057""(regulation of the force of heart contraction by chemical signal)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005113""(patched binding)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0005938""(cell cortex)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006940""(regulation of smooth muscle contraction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007595""(lactation)|go:""GO:0008104""(protein localization)|go:""GO:0008142""(oxysterol binding)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009617""(response to bacterium)|go:""GO:0010524""(positive regulation of calcium ion transport into cytosol)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0015031""(protein transport)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0016050""(vesicle organization)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0019065""(receptor-mediated endocytosis of virus by host cell)|go:""GO:0019217""(regulation of fatty acid metabolic process)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019915""(lipid storage)|go:""GO:0030154""(cell differentiation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030857""(negative regulation of epithelial cell differentiation)|go:""GO:0030879""(mammary gland development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032507""(maintenance of protein location in cell)|go:""GO:0032570""(response to progesterone)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033484""(intracellular nitric oxide homeostasis)|go:""GO:0034141""(positive regulation of toll-like receptor 3 signaling pathway)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038166""(angiotensin-activated signaling pathway)|go:""GO:0042310""(vasoconstriction)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043627""(response to estrogen)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044860""(protein localization to plasma membrane raft)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045019""(negative regulation of nitric oxide biosynthetic process)|go:""GO:0045121""(membrane raft)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048550""(negative regulation of pinocytosis)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051899""(membrane depolarization)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060355""(positive regulation of cell adhesion molecule production)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070320""(inward rectifier potassium channel inhibitor activity)|go:""GO:0070836""(caveola assembly)|go:""GO:0071218""(cellular response to misfolded protein)|go:""GO:0071360""(cellular response to exogenous dsRNA)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0071455""(cellular response to hyperoxia)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0098903""(regulation of membrane repolarization during action potential)|go:""GO:0098909""(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900027""(regulation of ruffle assembly)|go:""GO:1901380""(negative regulation of potassium ion transmembrane transport)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1903598""(positive regulation of gap junction assembly)|go:""GO:1903609""(negative regulation of inward rectifier potassium channel activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000535""(regulation of entry of bacterium into host cell)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR018361|mint:Q03135|rcsb pdb:7SC0|reactome:R-HSA-163560|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-210991|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9617828|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001744.2|dip:DIP-5960N|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:275777""|efo:""Orphanet:528""|panther:PTHR10844(orthology-group)"	"interpro:IPR018113|interpro:IPR001996(Phosphotransferase system, EIIB)|interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR013013(Phosphotransferase system, EIIC component, type 1)|interpro:IPR011296(Phosphotransferase system, trehalose-specific IIBC component)|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0015574""(trehalose transmembrane transporter activity)|go:""GO:0015771""(trehalose transport)|go:""GO:0016301""(kinase activity)|go:""GO:0090589""(protein-phosphocysteine-trehalose phosphotransferase system transporter activity)|interpro:IPR036878|interpro:IPR050558|panther:PTHR30175(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:+JhGp5YmhT3JLeTgHHBTHu9r34c9606	rogid:MIkTe/Rb+6LtHGd0IvWHhqfr8ao632	intact-crc:4BA17A76E67C4596|rigid:tCfQY4ejh4RskouZDEnT/k0tJ8M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULV8	uniprotkb:Q8CZZ7	intact:EBI-2341018|uniprotkb:Q9Y5Z3|uniprotkb:Q8N1E5|uniprotkb:Q9Y5Z2|ensembl:ENSP00000494162.1|intact:EBI-28975910	intact:EBI-2842831|uniprotkb:Q74W48	psi-mi:cblc_human(display_long)|uniprotkb:CBLC(gene name)|psi-mi:CBLC(display_short)|uniprotkb:CBL3(gene name synonym)|uniprotkb:RNF57(gene name synonym)|uniprotkb:SH3-binding protein CBL-C(gene name synonym)|uniprotkb:SH3-binding protein CBL-3(gene name synonym)|uniprotkb:RING finger protein 57(gene name synonym)|uniprotkb:Signal transduction protein CBL-C(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL-C(gene name synonym)	psi-mi:q8czz7_yerpe(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:YP_1051(locus name)|uniprotkb:y3075(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874248|imex:IM-13779-8134	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000142273.13(gene)|ensembl:ENST00000647358.2(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007175""(negative regulation of epidermal growth factor-activated receptor activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045121""(membrane raft)|go:""GO:0050821""(protein stabilization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:1990790""(response to glial cell derived neurotrophic factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|mint:Q9ULV8|rcsb pdb:3OP0|rcsb pdb:3VRN|rcsb pdb:3VRO|rcsb pdb:3VRP|rcsb pdb:3VRQ|rcsb pdb:3VRR|refseq:NP_001124324.1|refseq:NP_036248.3|ensembl:ENST00000341505.4|ensembl:ENSP00000340250.4|ensembl:ENSP00000494162.1|panther:PTHR23007(orthology-group)"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:syzTzR6RGJzLv2EpDirSrli4ghs9606	rogid:5D57QZRbHjtu2izZZ+54f7spmuk632	intact-crc:EF0DD9165B799A0F|rigid:Rn0a2oB1xRsehT/MRmwaQ0QsBTs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q03135	uniprotkb:Q8ZAQ2	intact:EBI-603614|uniprotkb:Q9UGP1|uniprotkb:Q9UNG1|uniprotkb:Q9UQH6|ensembl:ENSP00000339191.2	intact:EBI-2860892|uniprotkb:Q0WAR9	psi-mi:cav1_human(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)	psi-mi:thic_yerpe(display_long)|uniprotkb:thiC(gene name)|psi-mi:thiC(display_short)|uniprotkb:YP_3102(locus name)|uniprotkb:Hydroxymethylpyrimidine phosphate synthase(gene name synonym)|uniprotkb:YPO3739(locus name)|uniprotkb:y0491(locus name)|uniprotkb:Thiamine biosynthesis protein ThiC(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874262|imex:IM-13779-8133	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105974.13(gene)|ensembl:ENST00000341049.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001525""(angiogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0001960""(negative regulation of cytokine-mediated signaling pathway)|go:""GO:0002067""(glandular epithelial cell differentiation)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0002095""(caveolar macromolecular signaling complex)|go:""GO:0002931""(response to ischemia)|go:""GO:0003057""(regulation of the force of heart contraction by chemical signal)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005113""(patched binding)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005925""(focal adhesion)|go:""GO:0005929""(cilium)|go:""GO:0005938""(cell cortex)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006940""(regulation of smooth muscle contraction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007595""(lactation)|go:""GO:0008104""(protein localization)|go:""GO:0008142""(oxysterol binding)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009617""(response to bacterium)|go:""GO:0010524""(positive regulation of calcium ion transport into cytosol)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0015031""(protein transport)|go:""GO:0015485""(cholesterol binding)|go:""GO:0016020""(membrane)|go:""GO:0016050""(vesicle organization)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016504""(peptidase activator activity)|go:""GO:0019065""(receptor-mediated endocytosis of virus by host cell)|go:""GO:0019217""(regulation of fatty acid metabolic process)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019915""(lipid storage)|go:""GO:0030154""(cell differentiation)|go:""GO:0030193""(regulation of blood coagulation)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030857""(negative regulation of epithelial cell differentiation)|go:""GO:0030879""(mammary gland development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032507""(maintenance of protein location in cell)|go:""GO:0032570""(response to progesterone)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033484""(intracellular nitric oxide homeostasis)|go:""GO:0034141""(positive regulation of toll-like receptor 3 signaling pathway)|go:""GO:0038016""(insulin receptor internalization)|go:""GO:0038166""(angiotensin-activated signaling pathway)|go:""GO:0042310""(vasoconstriction)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043627""(response to estrogen)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044860""(protein localization to plasma membrane raft)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045019""(negative regulation of nitric oxide biosynthetic process)|go:""GO:0045121""(membrane raft)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048550""(negative regulation of pinocytosis)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051899""(membrane depolarization)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060355""(positive regulation of cell adhesion molecule production)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070320""(inward rectifier potassium channel inhibitor activity)|go:""GO:0070836""(caveola assembly)|go:""GO:0071218""(cellular response to misfolded protein)|go:""GO:0071360""(cellular response to exogenous dsRNA)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0071455""(cellular response to hyperoxia)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0098903""(regulation of membrane repolarization during action potential)|go:""GO:0098909""(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:""GO:0098911""(regulation of ventricular cardiac muscle cell action potential)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900027""(regulation of ruffle assembly)|go:""GO:1901380""(negative regulation of potassium ion transmembrane transport)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1903361""(protein localization to basolateral plasma membrane)|go:""GO:1903598""(positive regulation of gap junction assembly)|go:""GO:1903609""(negative regulation of inward rectifier potassium channel activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000535""(regulation of entry of bacterium into host cell)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR018361|mint:Q03135|rcsb pdb:7SC0|reactome:R-HSA-163560|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-210991|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9617828|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001744.2|dip:DIP-5960N|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:275777""|efo:""Orphanet:528""|panther:PTHR10844(orthology-group)"	"interpro:IPR002817(Thiamine biosynthesis protein ThiC)|refseq:WP_002210682.1|interpro:IPR025747|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0016830""(carbon-carbon lyase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR038521|interpro:IPR037509|refseq:YP_002348619.1|panther:PTHR30557(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:+JhGp5YmhT3JLeTgHHBTHu9r34c9606	rogid:RVZL9aFEqXV/KORpQabcnqvxVkE632	intact-crc:D2901266398CC308|rigid:wV1uMdJJGhz83jMi8u9alWS8pLk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIH1	uniprotkb:P07339	intact:EBI-2841326|uniprotkb:Q0WJD6	intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671.2	psi-mi:leud_yerpe(display_long)|uniprotkb:leuD(gene name)|psi-mi:leuD(display_short)|uniprotkb:Alpha-IPM isomerase(gene name synonym)|uniprotkb:Isopropylmalate isomerase(gene name synonym)|uniprotkb:YPO0530(locus name)|uniprotkb:y3648(locus name)|uniprotkb:YP_3652(locus name)	psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874308|imex:IM-13779-8138	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004431(3-isopropylmalate dehydratase, small subunit region)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|go:""GO:0003861""(3-isopropylmalate dehydratase activity)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009316""(3-isopropylmalate dehydratase complex)|refseq:WP_002210456.1|refseq:YP_002345602.1|interpro:IPR033940|interpro:IPR050075|panther:PTHR43345(orthology-group)"	"panther:PTHR47966(orthology-group)|dip:DIP-43906N|efo:""Orphanet:228337""|ensembl:ENSG00000117984.15(gene)|ensembl:ENST00000236671.7(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0004190""(aspartic-type endopeptidase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|go:""GO:0010008""(endosome membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0031904""(endosome lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0042159""(lipoprotein catabolic process)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070001""(aspartic-type peptidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070201""(regulation of establishment of protein localization)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-9018519|refseq:NP_001900.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:lF0EK380WhlR7ondVqFIwVAnDFQ632	rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606	intact-crc:D3CE0241F88158F0|rigid:BFlgUA7yh2tB+MdU+lMcHWwm/Cg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W2X2	uniprotkb:P07339	intact:EBI-2858818|uniprotkb:Q0WDU3|uniprotkb:Q74VZ3|uniprotkb:Q7CJW2|uniprotkb:A0A3N4AZS0|uniprotkb:A0A384LI09	intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671.2	psi-mi:a0a0h2w2x2_yerpe(display_long)|uniprotkb:YPO2589(locus name)	psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874294|imex:IM-13779-8139	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR007138(Antibiotic biosynthesis monooxygenase)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR050744|refseq:WP_002210309.1|refseq:YP_002347545.1	"panther:PTHR47966(orthology-group)|dip:DIP-43906N|efo:""Orphanet:228337""|ensembl:ENSG00000117984.15(gene)|ensembl:ENST00000236671.7(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0004190""(aspartic-type endopeptidase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|go:""GO:0010008""(endosome membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0031904""(endosome lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0042159""(lipoprotein catabolic process)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070001""(aspartic-type peptidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070201""(regulation of establishment of protein localization)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-9018519|refseq:NP_001900.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:0kEdI4fSZxkyWdmdTWZNGfmW9lM632	rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606	intact-crc:A6005D0AA7AAF102|rigid:1dUA3KtUUvKbVvHMxZ0XnrsuJdw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43234	uniprotkb:Q8ZI60	intact:EBI-2874283|ensembl:ENSP00000414904.3|ensembl:ENSP00000460395.1	intact:EBI-2867293|uniprotkb:Q0WJ16|uniprotkb:Q8CZS0|uniprotkb:Q74RQ3	psi-mi:cato_human(display_long)|uniprotkb:CTSO(gene name)|psi-mi:CTSO(display_short)|uniprotkb:CTSO1(gene name synonym)	psi-mi:hlde_yerpe(display_long)|uniprotkb:hldE(gene name)|psi-mi:hldE(display_short)|uniprotkb:rfaE(gene name synonym)|uniprotkb:waaE(gene name synonym)|uniprotkb:YPO0654(locus name)|uniprotkb:y3524(locus name)|uniprotkb:YP_2969(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874287|imex:IM-13779-8136	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001325.1|ensembl:ENSG00000256043.5(gene)|ensembl:ENSG00000263238.1(gene)|ensembl:ENST00000433477.4(transcript)|ensembl:ENST00000573499.1(transcript)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0006508""(proteolysis)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|interpro:IPR039417|reactome:R-HSA-2132295|panther:PTHR12411(orthology-group)"	"interpro:IPR023030|interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR002173(Carbohydrate/puine kinase, PfkB, conserved site)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR011913(RfaE bifunctional protein, domain I)|interpro:IPR011914(RfaE bifunctional protein, domain II)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR029056|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009244""(lipopolysaccharide core region biosynthetic process)|go:""GO:0016773""(phosphotransferase activity, alcohol group as acceptor)|go:""GO:0033785""(heptose 7-phosphate kinase activity)|go:""GO:0033786""(heptose-1-phosphate adenylyltransferase activity)|go:""GO:0097171""(ADP-L-glycero-beta-D-manno-heptose biosynthetic process)|refseq:YP_002345722.1|refseq:WP_002212193.1|panther:PTHR46969(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sMpYdop554cPYBp5Yj9N3YTfl589606	rogid:YjOg7DHiobhWysb8h+/w1bJnHOc632	intact-crc:1865A426CD904C38|rigid:6PZV3XnnT8fd3SVe+pmJTiwr/zI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CHW4	uniprotkb:P07339	intact:EBI-2848778|uniprotkb:Q74UT0	intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671.2	psi-mi:purt_yerpe(display_long)|uniprotkb:purT(gene name)|psi-mi:purT(display_short)|uniprotkb:5'-phosphoribosylglycinamide transformylase 2(gene name synonym)|uniprotkb:Formate-dependent GAR transformylase(gene name synonym)|uniprotkb:GAR transformylase 2(gene name synonym)|uniprotkb:Non-folate glycinamide ribonucleotide transformylase(gene name synonym)|uniprotkb:Phosphoribosylglycinamide formyltransferase 2(gene name synonym)|uniprotkb:YPO1775(locus name)|uniprotkb:YP_1618(locus name)|uniprotkb:y2533(locus name)	psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874301|imex:IM-13779-8137	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR003135(ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR005862(Phosphoribosylglycinamide formyltransferase 2)|interpro:IPR011054(Rudiment single hybrid motif)|refseq:WP_002211083.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004644""(phosphoribosylglycinamide formyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0043815""(phosphoribosylglycinamide formyltransferase 2 activity)|interpro:IPR048740|interpro:IPR054350|refseq:YP_002346772.1|panther:PTHR43055(orthology-group)"	"panther:PTHR47966(orthology-group)|dip:DIP-43906N|efo:""Orphanet:228337""|ensembl:ENSG00000117984.15(gene)|ensembl:ENST00000236671.7(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0004190""(aspartic-type endopeptidase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|go:""GO:0010008""(endosome membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0031904""(endosome lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0038020""(insulin receptor recycling)|go:""GO:0042159""(lipoprotein catabolic process)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070001""(aspartic-type peptidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070201""(regulation of establishment of protein localization)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:1901143""(insulin catabolic process)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-9018519|refseq:NP_001900.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:bCau0DjK5zfXGn3uk1MMfw6Caso632	rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606	intact-crc:DD17265126A8E4C7|rigid:ZZdOaIX4FWLlCSJZbvAPI8QvV8s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9RID8	uniprotkb:P25774	intact:EBI-2859217|uniprotkb:A0A3G5LBF7|uniprotkb:A0A384LNJ8|uniprotkb:Q7BTU6|uniprotkb:A0A2S9PDW1|uniprotkb:A0A380PG85	intact:EBI-2808345|uniprotkb:Q6FHS5|uniprotkb:Q9BUG3|uniprotkb:Q5T5I0|uniprotkb:D3DV05|uniprotkb:B4DWC9|ensembl:ENSP00000357981.3|ensembl:ENSP00000475176.2|ensembl:ENSP00000475557.2|ensembl:ENSP00000505359.1	psi-mi:q9rid8_yerpe(display_long)|uniprotkb:YPMT1.33(locus name)	psi-mi:cats_human(display_long)|uniprotkb:CTSS(gene name)|psi-mi:CTSS(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874276|imex:IM-13779-8140	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002214134.1|refseq:NP_857670.1|interpro:IPR003223(Flagellin phase1 repressor)|refseq:NP_395371.1|go:""GO:0003700""(DNA-binding transcription factor activity)"	"refseq:NP_004070.3|refseq:NP_001186668.1|ensembl:ENSG00000163131.12(gene)|ensembl:ENST00000368985.8(transcript)|ensembl:ENST00000472977.7(transcript)|ensembl:ENST00000607427.2(transcript)|ensembl:ENST00000681444.1(transcript)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006955""(immune response)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0010447""(response to acidic pH)|go:""GO:0016485""(protein processing)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030574""(collagen catabolic process)|go:""GO:0034769""(basement membrane disassembly)|go:""GO:0036021""(endolysosome lumen)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043236""(laminin binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048002""(antigen processing and presentation of peptide antigen)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0097067""(cellular response to thyroid hormone stimulus)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2001235""(positive regulation of apoptotic signaling pathway)|go:""GO:2001259""(positive regulation of cation channel activity)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR013201(Proteinase inhibitor I29, cathepsin propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|interpro:IPR039417|rcsb pdb:1GLO|rcsb pdb:1MS6|rcsb pdb:1NPZ|rcsb pdb:1NQC|rcsb pdb:2C0Y|rcsb pdb:2F1G|rcsb pdb:2FQ9|rcsb pdb:2FRA|rcsb pdb:2FRQ|rcsb pdb:2FT2|rcsb pdb:2FUD|rcsb pdb:2FYE|rcsb pdb:2G6D|rcsb pdb:2G7Y|rcsb pdb:2H7J|rcsb pdb:2HH5|rcsb pdb:2HHN|rcsb pdb:2HXZ|rcsb pdb:2OP3|rcsb pdb:2R9M|rcsb pdb:2R9N|rcsb pdb:2R9O|rcsb pdb:3IEJ|rcsb pdb:3N3G|rcsb pdb:3N4C|rcsb pdb:3OVX|rcsb pdb:4P6E|rcsb pdb:4P6G|rcsb pdb:5QBU|rcsb pdb:5QBV|rcsb pdb:5QBW|rcsb pdb:5QBX|rcsb pdb:5QBY|rcsb pdb:5QBZ|rcsb pdb:5QC0|rcsb pdb:5QC1|rcsb pdb:5QC2|rcsb pdb:5QC3|rcsb pdb:5QC4|rcsb pdb:5QC5|rcsb pdb:5QC6|rcsb pdb:5QC7|rcsb pdb:5QC8|rcsb pdb:5QC9|rcsb pdb:5QCA|rcsb pdb:5QCB|rcsb pdb:5QCC|rcsb pdb:5QCD|rcsb pdb:5QCE|rcsb pdb:5QCF|rcsb pdb:5QCG|rcsb pdb:5QCH|rcsb pdb:5QCI|rcsb pdb:5QCJ|rcsb pdb:6YYN|rcsb pdb:6YYO|rcsb pdb:6YYP|rcsb pdb:6YYQ|rcsb pdb:6YYR|rcsb pdb:8PI3|rcsb pdb:8RND|rcsb pdb:9GJ2|reactome:R-HSA-1236977|reactome:R-HSA-1474228|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|dip:DIP-61077N|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Gai8ohATJMOb+TpT/VpPGU9fdDw632	rogid:/47OYPCznvm6Z1si/zQXey+Nk0U9606	intact-crc:5CC834AB754A8847|rigid:OyYvXAvUzFnrsxHUy7HYmZfDPpQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHI8	uniprotkb:P53634	intact:EBI-2853665|uniprotkb:Q0WID5	intact:EBI-1047323|uniprotkb:A8K7V2|uniprotkb:Q53G93|uniprotkb:Q71E75|uniprotkb:Q71E76|uniprotkb:Q7M4N9|uniprotkb:Q8WY99|uniprotkb:Q8WYA7|uniprotkb:Q8WYA8|uniprotkb:Q7Z3G7|uniprotkb:Q7Z5U7|ensembl:ENSP00000227266.4|uniprotkb:B5MDD5|uniprotkb:Q2HIY8	"psi-mi:gcsp_yerpe(display_long)|uniprotkb:gcvP(gene name)|psi-mi:gcvP(display_short)|uniprotkb:Glycine cleavage system P-protein(gene name synonym)|uniprotkb:Glycine decarboxylase(gene name synonym)|uniprotkb:""Glycine dehydrogenase (aminomethyl-transferring)""(gene name synonym)|uniprotkb:YPO0905(locus name)|uniprotkb:YP_3602(locus name)|uniprotkb:y3292(locus name)"	psi-mi:catc_human(display_long)|uniprotkb:Dipeptidyl peptidase I(gene name synonym)|uniprotkb:Cathepsin C(gene name synonym)|uniprotkb:Cathepsin J(gene name synonym)|uniprotkb:Dipeptidyl transferase(gene name synonym)|uniprotkb:CTSC(gene name)|psi-mi:CTSC(display_short)|uniprotkb:CPPI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874329|imex:IM-13779-8141	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002209947.1|interpro:IPR020581|interpro:IPR003437(Glycine cleavage system P-protein)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:""GO:0004375""(""glycine dehydrogenase (decarboxylating) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0016594""(glycine binding)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR049315|interpro:IPR049316|refseq:YP_002345953.1|panther:PTHR11773(orthology-group)"	"ensembl:ENSG00000109861.17(gene)|ensembl:ENST00000227266.10(transcript)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005813""(centrosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006955""(immune response)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008239""(dipeptidyl-peptidase activity)|go:""GO:0016020""(membrane)|go:""GO:0016505""(peptidase activator activity involved in apoptotic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031404""(chloride ion binding)|go:""GO:0031642""(negative regulation of myelination)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903052""(positive regulation of proteolysis involved in protein catabolic process)|go:""GO:1903980""(positive regulation of microglial cell activation)|go:""GO:2001235""(positive regulation of apoptotic signaling pathway)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR014882(Cathepsin C exclusion)|interpro:IPR025660|interpro:IPR025661|interpro:IPR036496|interpro:IPR038765|interpro:IPR039412|mint:P53634|rcsb pdb:1K3B|rcsb pdb:2DJF|rcsb pdb:2DJG|rcsb pdb:3PDF|rcsb pdb:4CDC|rcsb pdb:4CDD|rcsb pdb:4CDE|rcsb pdb:4CDF|rcsb pdb:4OEL|rcsb pdb:4OEM|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-6798695|refseq:NP_001107645.1|refseq:NP_001805.3|refseq:NP_680475.1|efo:""Orphanet:2342""|efo:""Orphanet:678""|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DyITTFcMLNG19IvzD1ZE6K5EW/U632	rogid:vA2MxBAxHODNS4fo9Nvm6UJGW149606	intact-crc:52F7E5B2D4139FD4|rigid:sMl9Mrk8TIzeEMbaYryGMZUP8is	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D014	uniprotkb:P53634	intact:EBI-2840312|uniprotkb:Q74WE9	intact:EBI-1047323|uniprotkb:A8K7V2|uniprotkb:Q53G93|uniprotkb:Q71E75|uniprotkb:Q71E76|uniprotkb:Q7M4N9|uniprotkb:Q8WY99|uniprotkb:Q8WYA7|uniprotkb:Q8WYA8|uniprotkb:Q7Z3G7|uniprotkb:Q7Z5U7|ensembl:ENSP00000227266.4|uniprotkb:B5MDD5|uniprotkb:Q2HIY8	psi-mi:q8d014_yerpe(display_long)|uniprotkb:nrdB(gene name)|psi-mi:nrdB(display_short)|uniprotkb:y2975(locus name)|uniprotkb:YP_0924(locus name)	psi-mi:catc_human(display_long)|uniprotkb:Dipeptidyl peptidase I(gene name synonym)|uniprotkb:Cathepsin C(gene name synonym)|uniprotkb:Cathepsin J(gene name synonym)|uniprotkb:Dipeptidyl transferase(gene name synonym)|uniprotkb:CTSC(gene name)|psi-mi:CTSC(display_short)|uniprotkb:CPPI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874315|imex:IM-13779-8145	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033909|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|go:""GO:0004748""(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:""GO:0009263""(deoxyribonucleotide biosynthetic process)|interpro:IPR030475|interpro:IPR012348(Ribonucleotide reductase-related)"	"ensembl:ENSG00000109861.17(gene)|ensembl:ENST00000227266.10(transcript)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005813""(centrosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006955""(immune response)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008239""(dipeptidyl-peptidase activity)|go:""GO:0016020""(membrane)|go:""GO:0016505""(peptidase activator activity involved in apoptotic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031404""(chloride ion binding)|go:""GO:0031642""(negative regulation of myelination)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903052""(positive regulation of proteolysis involved in protein catabolic process)|go:""GO:1903980""(positive regulation of microglial cell activation)|go:""GO:2001235""(positive regulation of apoptotic signaling pathway)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR014882(Cathepsin C exclusion)|interpro:IPR025660|interpro:IPR025661|interpro:IPR036496|interpro:IPR038765|interpro:IPR039412|mint:P53634|rcsb pdb:1K3B|rcsb pdb:2DJF|rcsb pdb:2DJG|rcsb pdb:3PDF|rcsb pdb:4CDC|rcsb pdb:4CDD|rcsb pdb:4CDE|rcsb pdb:4CDF|rcsb pdb:4OEL|rcsb pdb:4OEM|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-6798695|refseq:NP_001107645.1|refseq:NP_001805.3|refseq:NP_680475.1|efo:""Orphanet:2342""|efo:""Orphanet:678""|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cQYray4oIRTe9sYOcO6GpVOCuBc632	rogid:vA2MxBAxHODNS4fo9Nvm6UJGW149606	intact-crc:1326CE0CD7979E39|rigid:33mR9jvX0VZ7tunP1IjpWA4hA20	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1P4	uniprotkb:P07858	intact:EBI-2845144	intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000342070.3|ensembl:ENSP00000345672.5|ensembl:ENSP00000431143.2|ensembl:ENSP00000431518.2|ensembl:ENSP00000432244.1|ensembl:ENSP00000432408.2|ensembl:ENSP00000433215.1|ensembl:ENSP00000433379.3|ensembl:ENSP00000433929.2|ensembl:ENSP00000434217.1|ensembl:ENSP00000434725.2|ensembl:ENSP00000435074.2|ensembl:ENSP00000435105.1|ensembl:ENSP00000435260.2|ensembl:ENSP00000435886.2|ensembl:ENSP00000493857.2|ensembl:ENSP00000494729.2|ensembl:ENSP00000502963.1|ensembl:ENSP00000503006.1|ensembl:ENSP00000503052.1|ensembl:ENSP00000503078.1|ensembl:ENSP00000503174.1|ensembl:ENSP00000503280.1|ensembl:ENSP00000503300.1|ensembl:ENSP00000503435.1|ensembl:ENSP00000503487.1|ensembl:ENSP00000503513.1|ensembl:ENSP00000503578.1|ensembl:ENSP00000503608.1|ensembl:ENSP00000503652.1|ensembl:ENSP00000503674.1|ensembl:ENSP00000503858.1|ensembl:ENSP00000503909.1|ensembl:ENSP00000504161.1|ensembl:ENSP00000504226.1|ensembl:ENSP00000504336.1|ensembl:ENSP00000504480.1|ensembl:ENSP00000504638.1|ensembl:ENSP00000504659.1|ensembl:ENSP00000504797.1|ensembl:ENSP00000518417.1|ensembl:ENSP00000518418.1|ensembl:ENSP00000518419.1|ensembl:ENSP00000518420.1|ensembl:ENSP00000518421.1|ensembl:ENSP00000518426.1|ensembl:ENSP00000518427.1|ensembl:ENSP00000518428.1|ensembl:ENSP00000518429.1|ensembl:ENSP00000518430.1|ensembl:ENSP00000518431.1|ensembl:ENSP00000518432.1|ensembl:ENSP00000518433.1|ensembl:ENSP00000518434.1|ensembl:ENSP00000518435.1|ensembl:ENSP00000518436.1|ensembl:ENSP00000518437.1|ensembl:ENSP00000518438.1|ensembl:ENSP00000518440.1|ensembl:ENSP00000518441.1|ensembl:ENSP00000518442.1|ensembl:ENSP00000518443.1|ensembl:ENSP00000518444.1|ensembl:ENSP00000518445.1|ensembl:ENSP00000518448.1|ensembl:ENSP00000518449.1|ensembl:ENSP00000518450.1|ensembl:ENSP00000518452.1|ensembl:ENSP00000518455.1|ensembl:ENSP00000518456.1|ensembl:ENSP00000518457.1|ensembl:ENSP00000518460.1|ensembl:ENSP00000518464.1|ensembl:ENSP00000518466.1|ensembl:ENSP00000518468.1|ensembl:ENSP00000518469.1	psi-mi:q8d1p4_yerpe(display_long)|uniprotkb:y0195(locus name)	psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874343|imex:IM-13779-8142	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR032712|interpro:IPR025263|interpro:IPR011836(Conserved hypothetical protein CHP02099)	"ensembl:ENSG00000164733.23(gene)|ensembl:ENSG00000285132.3(gene)|ensembl:ENST00000345125.8(transcript)|ensembl:ENST00000353047.11(transcript)|ensembl:ENST00000526645.6(transcript)|ensembl:ENST00000527215.7(transcript)|ensembl:ENST00000527243.6(transcript)|ensembl:ENST00000528965.3(transcript)|ensembl:ENST00000530296.6(transcript)|ensembl:ENST00000530640.7(transcript)|ensembl:ENST00000531089.6(transcript)|ensembl:ENST00000531502.6(transcript)|ensembl:ENST00000532392.3(transcript)|ensembl:ENST00000532656.7(transcript)|ensembl:ENST00000533455.6(transcript)|ensembl:ENST00000534382.6(transcript)|ensembl:ENST00000534510.6(transcript)|ensembl:ENST00000646105.3(transcript)|ensembl:ENST00000646239.2(transcript)|ensembl:ENST00000676691.1(transcript)|ensembl:ENST00000676755.1(transcript)|ensembl:ENST00000676825.1(transcript)|ensembl:ENST00000676843.1(transcript)|ensembl:ENST00000676952.1(transcript)|ensembl:ENST00000677082.1(transcript)|ensembl:ENST00000677366.1(transcript)|ensembl:ENST00000677415.1(transcript)|ensembl:ENST00000677418.1(transcript)|ensembl:ENST00000677544.1(transcript)|ensembl:ENST00000677650.1(transcript)|ensembl:ENST00000677671.1(transcript)|ensembl:ENST00000677819.1(transcript)|ensembl:ENST00000677873.1(transcript)|ensembl:ENST00000678092.1(transcript)|ensembl:ENST00000678145.1(transcript)|ensembl:ENST00000678242.1(transcript)|ensembl:ENST00000678357.1(transcript)|ensembl:ENST00000678615.1(transcript)|ensembl:ENST00000678929.1(transcript)|ensembl:ENST00000679051.1(transcript)|ensembl:ENST00000679128.1(transcript)|ensembl:ENST00000679140.1(transcript)|ensembl:ENST00000710700.1(transcript)|ensembl:ENST00000710702.1(transcript)|ensembl:ENST00000710703.1(transcript)|ensembl:ENST00000710704.1(transcript)|ensembl:ENST00000710705.1(transcript)|ensembl:ENST00000710713.1(transcript)|ensembl:ENST00000710714.1(transcript)|ensembl:ENST00000710715.1(transcript)|ensembl:ENST00000710716.1(transcript)|ensembl:ENST00000710717.1(transcript)|ensembl:ENST00000710718.1(transcript)|ensembl:ENST00000710719.1(transcript)|ensembl:ENST00000710720.1(transcript)|ensembl:ENST00000710721.1(transcript)|ensembl:ENST00000710722.1(transcript)|ensembl:ENST00000710723.1(transcript)|ensembl:ENST00000710724.1(transcript)|ensembl:ENST00000710725.1(transcript)|ensembl:ENST00000710727.1(transcript)|ensembl:ENST00000710728.1(transcript)|ensembl:ENST00000710729.1(transcript)|ensembl:ENST00000710730.1(transcript)|ensembl:ENST00000710731.1(transcript)|ensembl:ENST00000710732.1(transcript)|ensembl:ENST00000710743.1(transcript)|ensembl:ENST00000710744.1(transcript)|ensembl:ENST00000710745.1(transcript)|ensembl:ENST00000710747.1(transcript)|ensembl:ENST00000710750.1(transcript)|ensembl:ENST00000710751.1(transcript)|ensembl:ENST00000710752.1(transcript)|ensembl:ENST00000710755.1(transcript)|ensembl:ENST00000710759.1(transcript)|ensembl:ENST00000710761.1(transcript)|ensembl:ENST00000710763.1(transcript)|ensembl:ENST00000710764.1(transcript)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006590""(thyroid hormone generation)|go:""GO:0008233""(peptidase activity)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030574""(collagen catabolic process)|rcsb pdb:1CSB|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0036021""(endolysosome lumen)|go:""GO:0042470""(melanosome)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0046697""(decidualization)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097067""(cellular response to thyroid hormone stimulus)|go:""GO:1904090""(peptidase inhibitor complex)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|rcsb pdb:8B4T|rcsb pdb:8B5F|rcsb pdb:8HE9|rcsb pdb:8HEI|rcsb pdb:8HEN|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_006716307.1|refseq:XP_006716308.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|dip:DIP-42785N|efo:""Orphanet:50943""|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:k1ALZgWrTdqeyJ1mZBZgusKWD8Y632	rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606	intact-crc:59B48E6B0AF2EF4A|rigid:chfAx8dN3wEqjqlv2hHlBLYYo8I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P07858	uniprotkb:Q8ZJ07	intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000342070.3|ensembl:ENSP00000345672.5|ensembl:ENSP00000431143.2|ensembl:ENSP00000431518.2|ensembl:ENSP00000432244.1|ensembl:ENSP00000432408.2|ensembl:ENSP00000433215.1|ensembl:ENSP00000433379.3|ensembl:ENSP00000433929.2|ensembl:ENSP00000434217.1|ensembl:ENSP00000434725.2|ensembl:ENSP00000435074.2|ensembl:ENSP00000435105.1|ensembl:ENSP00000435260.2|ensembl:ENSP00000435886.2|ensembl:ENSP00000493857.2|ensembl:ENSP00000494729.2|ensembl:ENSP00000502963.1|ensembl:ENSP00000503006.1|ensembl:ENSP00000503052.1|ensembl:ENSP00000503078.1|ensembl:ENSP00000503174.1|ensembl:ENSP00000503280.1|ensembl:ENSP00000503300.1|ensembl:ENSP00000503435.1|ensembl:ENSP00000503487.1|ensembl:ENSP00000503513.1|ensembl:ENSP00000503578.1|ensembl:ENSP00000503608.1|ensembl:ENSP00000503652.1|ensembl:ENSP00000503674.1|ensembl:ENSP00000503858.1|ensembl:ENSP00000503909.1|ensembl:ENSP00000504161.1|ensembl:ENSP00000504226.1|ensembl:ENSP00000504336.1|ensembl:ENSP00000504480.1|ensembl:ENSP00000504638.1|ensembl:ENSP00000504659.1|ensembl:ENSP00000504797.1|ensembl:ENSP00000518417.1|ensembl:ENSP00000518418.1|ensembl:ENSP00000518419.1|ensembl:ENSP00000518420.1|ensembl:ENSP00000518421.1|ensembl:ENSP00000518426.1|ensembl:ENSP00000518427.1|ensembl:ENSP00000518428.1|ensembl:ENSP00000518429.1|ensembl:ENSP00000518430.1|ensembl:ENSP00000518431.1|ensembl:ENSP00000518432.1|ensembl:ENSP00000518433.1|ensembl:ENSP00000518434.1|ensembl:ENSP00000518435.1|ensembl:ENSP00000518436.1|ensembl:ENSP00000518437.1|ensembl:ENSP00000518438.1|ensembl:ENSP00000518440.1|ensembl:ENSP00000518441.1|ensembl:ENSP00000518442.1|ensembl:ENSP00000518443.1|ensembl:ENSP00000518444.1|ensembl:ENSP00000518445.1|ensembl:ENSP00000518448.1|ensembl:ENSP00000518449.1|ensembl:ENSP00000518450.1|ensembl:ENSP00000518452.1|ensembl:ENSP00000518455.1|ensembl:ENSP00000518456.1|ensembl:ENSP00000518457.1|ensembl:ENSP00000518460.1|ensembl:ENSP00000518464.1|ensembl:ENSP00000518466.1|ensembl:ENSP00000518468.1|ensembl:ENSP00000518469.1	intact:EBI-2862664|uniprotkb:Q0WJY4	psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym)	psi-mi:uvra_yerpe(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:YPO0324(locus name)|uniprotkb:y0580(locus name)|uniprotkb:YP_0479(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874336|imex:IM-13779-8143	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164733.23(gene)|ensembl:ENSG00000285132.3(gene)|ensembl:ENST00000345125.8(transcript)|ensembl:ENST00000353047.11(transcript)|ensembl:ENST00000526645.6(transcript)|ensembl:ENST00000527215.7(transcript)|ensembl:ENST00000527243.6(transcript)|ensembl:ENST00000528965.3(transcript)|ensembl:ENST00000530296.6(transcript)|ensembl:ENST00000530640.7(transcript)|ensembl:ENST00000531089.6(transcript)|ensembl:ENST00000531502.6(transcript)|ensembl:ENST00000532392.3(transcript)|ensembl:ENST00000532656.7(transcript)|ensembl:ENST00000533455.6(transcript)|ensembl:ENST00000534382.6(transcript)|ensembl:ENST00000534510.6(transcript)|ensembl:ENST00000646105.3(transcript)|ensembl:ENST00000646239.2(transcript)|ensembl:ENST00000676691.1(transcript)|ensembl:ENST00000676755.1(transcript)|ensembl:ENST00000676825.1(transcript)|ensembl:ENST00000676843.1(transcript)|ensembl:ENST00000676952.1(transcript)|ensembl:ENST00000677082.1(transcript)|ensembl:ENST00000677366.1(transcript)|ensembl:ENST00000677415.1(transcript)|ensembl:ENST00000677418.1(transcript)|ensembl:ENST00000677544.1(transcript)|ensembl:ENST00000677650.1(transcript)|ensembl:ENST00000677671.1(transcript)|ensembl:ENST00000677819.1(transcript)|ensembl:ENST00000677873.1(transcript)|ensembl:ENST00000678092.1(transcript)|ensembl:ENST00000678145.1(transcript)|ensembl:ENST00000678242.1(transcript)|ensembl:ENST00000678357.1(transcript)|ensembl:ENST00000678615.1(transcript)|ensembl:ENST00000678929.1(transcript)|ensembl:ENST00000679051.1(transcript)|ensembl:ENST00000679128.1(transcript)|ensembl:ENST00000679140.1(transcript)|ensembl:ENST00000710700.1(transcript)|ensembl:ENST00000710702.1(transcript)|ensembl:ENST00000710703.1(transcript)|ensembl:ENST00000710704.1(transcript)|ensembl:ENST00000710705.1(transcript)|ensembl:ENST00000710713.1(transcript)|ensembl:ENST00000710714.1(transcript)|ensembl:ENST00000710715.1(transcript)|ensembl:ENST00000710716.1(transcript)|ensembl:ENST00000710717.1(transcript)|ensembl:ENST00000710718.1(transcript)|ensembl:ENST00000710719.1(transcript)|ensembl:ENST00000710720.1(transcript)|ensembl:ENST00000710721.1(transcript)|ensembl:ENST00000710722.1(transcript)|ensembl:ENST00000710723.1(transcript)|ensembl:ENST00000710724.1(transcript)|ensembl:ENST00000710725.1(transcript)|ensembl:ENST00000710727.1(transcript)|ensembl:ENST00000710728.1(transcript)|ensembl:ENST00000710729.1(transcript)|ensembl:ENST00000710730.1(transcript)|ensembl:ENST00000710731.1(transcript)|ensembl:ENST00000710732.1(transcript)|ensembl:ENST00000710743.1(transcript)|ensembl:ENST00000710744.1(transcript)|ensembl:ENST00000710745.1(transcript)|ensembl:ENST00000710747.1(transcript)|ensembl:ENST00000710750.1(transcript)|ensembl:ENST00000710751.1(transcript)|ensembl:ENST00000710752.1(transcript)|ensembl:ENST00000710755.1(transcript)|ensembl:ENST00000710759.1(transcript)|ensembl:ENST00000710761.1(transcript)|ensembl:ENST00000710763.1(transcript)|ensembl:ENST00000710764.1(transcript)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006590""(thyroid hormone generation)|go:""GO:0008233""(peptidase activity)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030574""(collagen catabolic process)|rcsb pdb:1CSB|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0036021""(endolysosome lumen)|go:""GO:0042470""(melanosome)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0046697""(decidualization)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097067""(cellular response to thyroid hormone stimulus)|go:""GO:1904090""(peptidase inhibitor complex)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|rcsb pdb:8B4T|rcsb pdb:8B5F|rcsb pdb:8HE9|rcsb pdb:8HEI|rcsb pdb:8HEN|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_006716307.1|refseq:XP_006716308.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|dip:DIP-42785N|efo:""Orphanet:50943""|panther:PTHR12411(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|interpro:IPR027417|refseq:WP_002209099.1|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR041102|interpro:IPR041552|refseq:YP_002345404.1|interpro:IPR013815(ATP-grasp fold, subdomain 1)|panther:PTHR43152(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606	rogid:3YrM2RVQkyTivw5n1TtLhIWMTlw632	intact-crc:CA9A36D50A00C1EB|rigid:Lyhf3UEL/yDph/z/VIwPIHSA3Js	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YCT6	uniprotkb:P53634	intact:EBI-2845671|uniprotkb:Q74QB9|uniprotkb:Q0WIG8|uniprotkb:Q7CGU7|uniprotkb:A0A384L4P0	intact:EBI-1047323|uniprotkb:A8K7V2|uniprotkb:Q53G93|uniprotkb:Q71E75|uniprotkb:Q71E76|uniprotkb:Q7M4N9|uniprotkb:Q8WY99|uniprotkb:Q8WYA7|uniprotkb:Q8WYA8|uniprotkb:Q7Z3G7|uniprotkb:Q7Z5U7|ensembl:ENSP00000227266.4|uniprotkb:B5MDD5|uniprotkb:Q2HIY8	psi-mi:a0a5p8yct6_yerpe(display_long)|uniprotkb:YPO0870(locus name)	psi-mi:catc_human(display_long)|uniprotkb:Dipeptidyl peptidase I(gene name synonym)|uniprotkb:Cathepsin C(gene name synonym)|uniprotkb:Cathepsin J(gene name synonym)|uniprotkb:Dipeptidyl transferase(gene name synonym)|uniprotkb:CTSC(gene name)|psi-mi:CTSC(display_short)|uniprotkb:CPPI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874322|imex:IM-13779-8144	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_002345920.1	"ensembl:ENSG00000109861.17(gene)|ensembl:ENST00000227266.10(transcript)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005813""(centrosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006955""(immune response)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008239""(dipeptidyl-peptidase activity)|go:""GO:0016020""(membrane)|go:""GO:0016505""(peptidase activator activity involved in apoptotic process)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031404""(chloride ion binding)|go:""GO:0031642""(negative regulation of myelination)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903052""(positive regulation of proteolysis involved in protein catabolic process)|go:""GO:1903980""(positive regulation of microglial cell activation)|go:""GO:2001235""(positive regulation of apoptotic signaling pathway)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR014882(Cathepsin C exclusion)|interpro:IPR025660|interpro:IPR025661|interpro:IPR036496|interpro:IPR038765|interpro:IPR039412|mint:P53634|rcsb pdb:1K3B|rcsb pdb:2DJF|rcsb pdb:2DJG|rcsb pdb:3PDF|rcsb pdb:4CDC|rcsb pdb:4CDD|rcsb pdb:4CDE|rcsb pdb:4CDF|rcsb pdb:4OEL|rcsb pdb:4OEM|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-6798695|refseq:NP_001107645.1|refseq:NP_001805.3|refseq:NP_680475.1|efo:""Orphanet:2342""|efo:""Orphanet:678""|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AOWwmv4Vb6xHJQUvmRTiMlJYQCA632	rogid:vA2MxBAxHODNS4fo9Nvm6UJGW149606	intact-crc:D0B7414B7A0E28CF|rigid:+izDDvejXj6D3zU+kDmS9Qcf6ZY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P07858	uniprotkb:Q8ZDA6	intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000342070.3|ensembl:ENSP00000345672.5|ensembl:ENSP00000431143.2|ensembl:ENSP00000431518.2|ensembl:ENSP00000432244.1|ensembl:ENSP00000432408.2|ensembl:ENSP00000433215.1|ensembl:ENSP00000433379.3|ensembl:ENSP00000433929.2|ensembl:ENSP00000434217.1|ensembl:ENSP00000434725.2|ensembl:ENSP00000435074.2|ensembl:ENSP00000435105.1|ensembl:ENSP00000435260.2|ensembl:ENSP00000435886.2|ensembl:ENSP00000493857.2|ensembl:ENSP00000494729.2|ensembl:ENSP00000502963.1|ensembl:ENSP00000503006.1|ensembl:ENSP00000503052.1|ensembl:ENSP00000503078.1|ensembl:ENSP00000503174.1|ensembl:ENSP00000503280.1|ensembl:ENSP00000503300.1|ensembl:ENSP00000503435.1|ensembl:ENSP00000503487.1|ensembl:ENSP00000503513.1|ensembl:ENSP00000503578.1|ensembl:ENSP00000503608.1|ensembl:ENSP00000503652.1|ensembl:ENSP00000503674.1|ensembl:ENSP00000503858.1|ensembl:ENSP00000503909.1|ensembl:ENSP00000504161.1|ensembl:ENSP00000504226.1|ensembl:ENSP00000504336.1|ensembl:ENSP00000504480.1|ensembl:ENSP00000504638.1|ensembl:ENSP00000504659.1|ensembl:ENSP00000504797.1|ensembl:ENSP00000518417.1|ensembl:ENSP00000518418.1|ensembl:ENSP00000518419.1|ensembl:ENSP00000518420.1|ensembl:ENSP00000518421.1|ensembl:ENSP00000518426.1|ensembl:ENSP00000518427.1|ensembl:ENSP00000518428.1|ensembl:ENSP00000518429.1|ensembl:ENSP00000518430.1|ensembl:ENSP00000518431.1|ensembl:ENSP00000518432.1|ensembl:ENSP00000518433.1|ensembl:ENSP00000518434.1|ensembl:ENSP00000518435.1|ensembl:ENSP00000518436.1|ensembl:ENSP00000518437.1|ensembl:ENSP00000518438.1|ensembl:ENSP00000518440.1|ensembl:ENSP00000518441.1|ensembl:ENSP00000518442.1|ensembl:ENSP00000518443.1|ensembl:ENSP00000518444.1|ensembl:ENSP00000518445.1|ensembl:ENSP00000518448.1|ensembl:ENSP00000518449.1|ensembl:ENSP00000518450.1|ensembl:ENSP00000518452.1|ensembl:ENSP00000518455.1|ensembl:ENSP00000518456.1|ensembl:ENSP00000518457.1|ensembl:ENSP00000518460.1|ensembl:ENSP00000518464.1|ensembl:ENSP00000518466.1|ensembl:ENSP00000518468.1|ensembl:ENSP00000518469.1	intact:EBI-2843773|uniprotkb:Q0WDK8	psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym)	psi-mi:chbg_yerpe(display_long)|uniprotkb:chbG(gene name)|psi-mi:chbG(display_short)|uniprotkb:Chitin disaccharide deacetylase(gene name synonym)|uniprotkb:Chitobiose deacetylase(gene name synonym)|uniprotkb:Chitobiose-6P deacetylase(gene name synonym)|uniprotkb:Chitotriose deacetylase(gene name synonym)|uniprotkb:Chitotriose-6P deacetylase(gene name synonym)|uniprotkb:YPO2682(locus name)|uniprotkb:YP_2484(locus name)|uniprotkb:y1255(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874364|imex:IM-13779-8149	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164733.23(gene)|ensembl:ENSG00000285132.3(gene)|ensembl:ENST00000345125.8(transcript)|ensembl:ENST00000353047.11(transcript)|ensembl:ENST00000526645.6(transcript)|ensembl:ENST00000527215.7(transcript)|ensembl:ENST00000527243.6(transcript)|ensembl:ENST00000528965.3(transcript)|ensembl:ENST00000530296.6(transcript)|ensembl:ENST00000530640.7(transcript)|ensembl:ENST00000531089.6(transcript)|ensembl:ENST00000531502.6(transcript)|ensembl:ENST00000532392.3(transcript)|ensembl:ENST00000532656.7(transcript)|ensembl:ENST00000533455.6(transcript)|ensembl:ENST00000534382.6(transcript)|ensembl:ENST00000534510.6(transcript)|ensembl:ENST00000646105.3(transcript)|ensembl:ENST00000646239.2(transcript)|ensembl:ENST00000676691.1(transcript)|ensembl:ENST00000676755.1(transcript)|ensembl:ENST00000676825.1(transcript)|ensembl:ENST00000676843.1(transcript)|ensembl:ENST00000676952.1(transcript)|ensembl:ENST00000677082.1(transcript)|ensembl:ENST00000677366.1(transcript)|ensembl:ENST00000677415.1(transcript)|ensembl:ENST00000677418.1(transcript)|ensembl:ENST00000677544.1(transcript)|ensembl:ENST00000677650.1(transcript)|ensembl:ENST00000677671.1(transcript)|ensembl:ENST00000677819.1(transcript)|ensembl:ENST00000677873.1(transcript)|ensembl:ENST00000678092.1(transcript)|ensembl:ENST00000678145.1(transcript)|ensembl:ENST00000678242.1(transcript)|ensembl:ENST00000678357.1(transcript)|ensembl:ENST00000678615.1(transcript)|ensembl:ENST00000678929.1(transcript)|ensembl:ENST00000679051.1(transcript)|ensembl:ENST00000679128.1(transcript)|ensembl:ENST00000679140.1(transcript)|ensembl:ENST00000710700.1(transcript)|ensembl:ENST00000710702.1(transcript)|ensembl:ENST00000710703.1(transcript)|ensembl:ENST00000710704.1(transcript)|ensembl:ENST00000710705.1(transcript)|ensembl:ENST00000710713.1(transcript)|ensembl:ENST00000710714.1(transcript)|ensembl:ENST00000710715.1(transcript)|ensembl:ENST00000710716.1(transcript)|ensembl:ENST00000710717.1(transcript)|ensembl:ENST00000710718.1(transcript)|ensembl:ENST00000710719.1(transcript)|ensembl:ENST00000710720.1(transcript)|ensembl:ENST00000710721.1(transcript)|ensembl:ENST00000710722.1(transcript)|ensembl:ENST00000710723.1(transcript)|ensembl:ENST00000710724.1(transcript)|ensembl:ENST00000710725.1(transcript)|ensembl:ENST00000710727.1(transcript)|ensembl:ENST00000710728.1(transcript)|ensembl:ENST00000710729.1(transcript)|ensembl:ENST00000710730.1(transcript)|ensembl:ENST00000710731.1(transcript)|ensembl:ENST00000710732.1(transcript)|ensembl:ENST00000710743.1(transcript)|ensembl:ENST00000710744.1(transcript)|ensembl:ENST00000710745.1(transcript)|ensembl:ENST00000710747.1(transcript)|ensembl:ENST00000710750.1(transcript)|ensembl:ENST00000710751.1(transcript)|ensembl:ENST00000710752.1(transcript)|ensembl:ENST00000710755.1(transcript)|ensembl:ENST00000710759.1(transcript)|ensembl:ENST00000710761.1(transcript)|ensembl:ENST00000710763.1(transcript)|ensembl:ENST00000710764.1(transcript)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006590""(thyroid hormone generation)|go:""GO:0008233""(peptidase activity)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030574""(collagen catabolic process)|rcsb pdb:1CSB|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0036021""(endolysosome lumen)|go:""GO:0042470""(melanosome)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0046697""(decidualization)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097067""(cellular response to thyroid hormone stimulus)|go:""GO:1904090""(peptidase inhibitor complex)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|rcsb pdb:8B4T|rcsb pdb:8B5F|rcsb pdb:8HE9|rcsb pdb:8HEI|rcsb pdb:8HEN|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_006716307.1|refseq:XP_006716308.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|dip:DIP-42785N|efo:""Orphanet:50943""|panther:PTHR12411(orthology-group)"	"interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR006879(YdjC-like protein)|interpro:IPR022948|go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0005737""(cytoplasm)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0019213""(deacetylase activity)|go:""GO:0036311""(chitin disaccharide deacetylase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0052777""(diacetylchitobiose catabolic process)|refseq:WP_002212244.1|refseq:YP_002347630.1|panther:PTHR31609(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606	rogid:pYqUZfBmwRlqczCS0iM02q3LMNo632	intact-crc:E99F98D50A4E9169|rigid:k+a5XGjFrUSRX89uxfR319qpAzQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04040	uniprotkb:O68769	intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052.4	intact:EBI-2845621|uniprotkb:A0A384LBJ7|uniprotkb:Q74YJ8|uniprotkb:Q7ARC7|uniprotkb:Q7BT03|uniprotkb:A0A3G5LHP7|uniprotkb:A0A1U8QJV7|uniprotkb:A0A2U2H212	psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short)	psi-mi:o68769_yerpe(display_long)|uniprotkb:YPMT1.55c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874378|imex:IM-13779-8148	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000121691.7(gene)|ensembl:ENST00000241052.5(transcript)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001657""(ureteric bud development)|go:""GO:0001666""(response to hypoxia)|go:""GO:0004046""(aminoacylase activity)|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0009060""(aerobic respiration)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009642""(response to light intensity)|go:""GO:0009650""(UV protection)|go:""GO:0010193""(response to ozone)|go:""GO:0010288""(response to lead ion)|go:""GO:0014823""(response to activity)|go:""GO:0014854""(response to inactivity)|go:""GO:0016020""(membrane)|go:""GO:0016209""(antioxidant activity)|go:""GO:0016684""(oxidoreductase activity, acting on peroxide as acceptor)|go:""GO:0019899""(enzyme binding)|go:""GO:0020027""(hemoglobin metabolic process)|go:""GO:0020037""(heme binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032868""(response to insulin)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033189""(response to vitamin A)|go:""GO:0033197""(response to vitamin E)|go:""GO:0033591""(response to L-ascorbic acid)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045471""(response to ethanol)|go:""GO:0046686""(response to cadmium ion)|go:""GO:0046872""(metal ion binding)|go:""GO:0050661""(NADP binding)|go:""GO:0051781""(positive regulation of cell division)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0062151""(catalase complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070542""(response to fatty acid)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072722""(response to amitrole)|go:""GO:0080184""(response to phenylpropanoid)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|rcsb pdb:7P8W|rcsb pdb:7VD9|rcsb pdb:8EL9|rcsb pdb:8HID|rcsb pdb:8PVD|rcsb pdb:8SGV|rcsb pdb:8WZH|rcsb pdb:8WZJ|rcsb pdb:8WZK|rcsb pdb:8WZM|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017|reactome:R-HSA-9841251|refseq:NP_001743.1|efo:""Orphanet:926""|panther:PTHR11465(orthology-group)"	"refseq:NP_395400.1|refseq:YP_093945.1|refseq:NP_857688.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|refseq:WP_002213143.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606	rogid:nQbvf/FMyfPAI9dWsYFXKmJ70HI632	intact-crc:C783EBF17376C01E|rigid:LQyR/jvItFTL+S0V/5QrirUbEMo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZG09	uniprotkb:P07858	intact:EBI-2842762|uniprotkb:Q74VB1|uniprotkb:Q7CHQ5|uniprotkb:Q0WGR1	intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000342070.3|ensembl:ENSP00000345672.5|ensembl:ENSP00000431143.2|ensembl:ENSP00000431518.2|ensembl:ENSP00000432244.1|ensembl:ENSP00000432408.2|ensembl:ENSP00000433215.1|ensembl:ENSP00000433379.3|ensembl:ENSP00000433929.2|ensembl:ENSP00000434217.1|ensembl:ENSP00000434725.2|ensembl:ENSP00000435074.2|ensembl:ENSP00000435105.1|ensembl:ENSP00000435260.2|ensembl:ENSP00000435886.2|ensembl:ENSP00000493857.2|ensembl:ENSP00000494729.2|ensembl:ENSP00000502963.1|ensembl:ENSP00000503006.1|ensembl:ENSP00000503052.1|ensembl:ENSP00000503078.1|ensembl:ENSP00000503174.1|ensembl:ENSP00000503280.1|ensembl:ENSP00000503300.1|ensembl:ENSP00000503435.1|ensembl:ENSP00000503487.1|ensembl:ENSP00000503513.1|ensembl:ENSP00000503578.1|ensembl:ENSP00000503608.1|ensembl:ENSP00000503652.1|ensembl:ENSP00000503674.1|ensembl:ENSP00000503858.1|ensembl:ENSP00000503909.1|ensembl:ENSP00000504161.1|ensembl:ENSP00000504226.1|ensembl:ENSP00000504336.1|ensembl:ENSP00000504480.1|ensembl:ENSP00000504638.1|ensembl:ENSP00000504659.1|ensembl:ENSP00000504797.1|ensembl:ENSP00000518417.1|ensembl:ENSP00000518418.1|ensembl:ENSP00000518419.1|ensembl:ENSP00000518420.1|ensembl:ENSP00000518421.1|ensembl:ENSP00000518426.1|ensembl:ENSP00000518427.1|ensembl:ENSP00000518428.1|ensembl:ENSP00000518429.1|ensembl:ENSP00000518430.1|ensembl:ENSP00000518431.1|ensembl:ENSP00000518432.1|ensembl:ENSP00000518433.1|ensembl:ENSP00000518434.1|ensembl:ENSP00000518435.1|ensembl:ENSP00000518436.1|ensembl:ENSP00000518437.1|ensembl:ENSP00000518438.1|ensembl:ENSP00000518440.1|ensembl:ENSP00000518441.1|ensembl:ENSP00000518442.1|ensembl:ENSP00000518443.1|ensembl:ENSP00000518444.1|ensembl:ENSP00000518445.1|ensembl:ENSP00000518448.1|ensembl:ENSP00000518449.1|ensembl:ENSP00000518450.1|ensembl:ENSP00000518452.1|ensembl:ENSP00000518455.1|ensembl:ENSP00000518456.1|ensembl:ENSP00000518457.1|ensembl:ENSP00000518460.1|ensembl:ENSP00000518464.1|ensembl:ENSP00000518466.1|ensembl:ENSP00000518468.1|ensembl:ENSP00000518469.1	psi-mi:mao1_yerpe(display_long)|uniprotkb:maeA(gene name)|psi-mi:maeA(display_short)|uniprotkb:YPO1511(locus name)|uniprotkb:y2658(locus name)|uniprotkb:YP_1401(locus name)	psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874357|imex:IM-13779-8146	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR001891(Malic oxidoreductase)|interpro:IPR023667|go:""GO:0004470""(malic enzyme activity)|go:""GO:0004471""(""malate dehydrogenase (decarboxylating) (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006108""(malate metabolic process)|go:""GO:0008948""(oxaloacetate decarboxylase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051287""(NAD binding)|refseq:WP_002211968.1|interpro:IPR036291|interpro:IPR037062|refseq:YP_002346527.1|interpro:IPR046346|panther:PTHR23406(orthology-group)"	"ensembl:ENSG00000164733.23(gene)|ensembl:ENSG00000285132.3(gene)|ensembl:ENST00000345125.8(transcript)|ensembl:ENST00000353047.11(transcript)|ensembl:ENST00000526645.6(transcript)|ensembl:ENST00000527215.7(transcript)|ensembl:ENST00000527243.6(transcript)|ensembl:ENST00000528965.3(transcript)|ensembl:ENST00000530296.6(transcript)|ensembl:ENST00000530640.7(transcript)|ensembl:ENST00000531089.6(transcript)|ensembl:ENST00000531502.6(transcript)|ensembl:ENST00000532392.3(transcript)|ensembl:ENST00000532656.7(transcript)|ensembl:ENST00000533455.6(transcript)|ensembl:ENST00000534382.6(transcript)|ensembl:ENST00000534510.6(transcript)|ensembl:ENST00000646105.3(transcript)|ensembl:ENST00000646239.2(transcript)|ensembl:ENST00000676691.1(transcript)|ensembl:ENST00000676755.1(transcript)|ensembl:ENST00000676825.1(transcript)|ensembl:ENST00000676843.1(transcript)|ensembl:ENST00000676952.1(transcript)|ensembl:ENST00000677082.1(transcript)|ensembl:ENST00000677366.1(transcript)|ensembl:ENST00000677415.1(transcript)|ensembl:ENST00000677418.1(transcript)|ensembl:ENST00000677544.1(transcript)|ensembl:ENST00000677650.1(transcript)|ensembl:ENST00000677671.1(transcript)|ensembl:ENST00000677819.1(transcript)|ensembl:ENST00000677873.1(transcript)|ensembl:ENST00000678092.1(transcript)|ensembl:ENST00000678145.1(transcript)|ensembl:ENST00000678242.1(transcript)|ensembl:ENST00000678357.1(transcript)|ensembl:ENST00000678615.1(transcript)|ensembl:ENST00000678929.1(transcript)|ensembl:ENST00000679051.1(transcript)|ensembl:ENST00000679128.1(transcript)|ensembl:ENST00000679140.1(transcript)|ensembl:ENST00000710700.1(transcript)|ensembl:ENST00000710702.1(transcript)|ensembl:ENST00000710703.1(transcript)|ensembl:ENST00000710704.1(transcript)|ensembl:ENST00000710705.1(transcript)|ensembl:ENST00000710713.1(transcript)|ensembl:ENST00000710714.1(transcript)|ensembl:ENST00000710715.1(transcript)|ensembl:ENST00000710716.1(transcript)|ensembl:ENST00000710717.1(transcript)|ensembl:ENST00000710718.1(transcript)|ensembl:ENST00000710719.1(transcript)|ensembl:ENST00000710720.1(transcript)|ensembl:ENST00000710721.1(transcript)|ensembl:ENST00000710722.1(transcript)|ensembl:ENST00000710723.1(transcript)|ensembl:ENST00000710724.1(transcript)|ensembl:ENST00000710725.1(transcript)|ensembl:ENST00000710727.1(transcript)|ensembl:ENST00000710728.1(transcript)|ensembl:ENST00000710729.1(transcript)|ensembl:ENST00000710730.1(transcript)|ensembl:ENST00000710731.1(transcript)|ensembl:ENST00000710732.1(transcript)|ensembl:ENST00000710743.1(transcript)|ensembl:ENST00000710744.1(transcript)|ensembl:ENST00000710745.1(transcript)|ensembl:ENST00000710747.1(transcript)|ensembl:ENST00000710750.1(transcript)|ensembl:ENST00000710751.1(transcript)|ensembl:ENST00000710752.1(transcript)|ensembl:ENST00000710755.1(transcript)|ensembl:ENST00000710759.1(transcript)|ensembl:ENST00000710761.1(transcript)|ensembl:ENST00000710763.1(transcript)|ensembl:ENST00000710764.1(transcript)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006590""(thyroid hormone generation)|go:""GO:0008233""(peptidase activity)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030574""(collagen catabolic process)|rcsb pdb:1CSB|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0036021""(endolysosome lumen)|go:""GO:0042470""(melanosome)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0046697""(decidualization)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097067""(cellular response to thyroid hormone stimulus)|go:""GO:1904090""(peptidase inhibitor complex)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|rcsb pdb:8B4T|rcsb pdb:8B5F|rcsb pdb:8HE9|rcsb pdb:8HEI|rcsb pdb:8HEN|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_006716307.1|refseq:XP_006716308.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|dip:DIP-42785N|efo:""Orphanet:50943""|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:3qTE5pPHB/ePJ+WGe7JGTqu1xJA632	rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606	intact-crc:B1D90BD5092D3AFF|rigid:lmHXuknk+XpLua4wkORjGq5bdnk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P07858	uniprotkb:Q7ARD3	intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000342070.3|ensembl:ENSP00000345672.5|ensembl:ENSP00000431143.2|ensembl:ENSP00000431518.2|ensembl:ENSP00000432244.1|ensembl:ENSP00000432408.2|ensembl:ENSP00000433215.1|ensembl:ENSP00000433379.3|ensembl:ENSP00000433929.2|ensembl:ENSP00000434217.1|ensembl:ENSP00000434725.2|ensembl:ENSP00000435074.2|ensembl:ENSP00000435105.1|ensembl:ENSP00000435260.2|ensembl:ENSP00000435886.2|ensembl:ENSP00000493857.2|ensembl:ENSP00000494729.2|ensembl:ENSP00000502963.1|ensembl:ENSP00000503006.1|ensembl:ENSP00000503052.1|ensembl:ENSP00000503078.1|ensembl:ENSP00000503174.1|ensembl:ENSP00000503280.1|ensembl:ENSP00000503300.1|ensembl:ENSP00000503435.1|ensembl:ENSP00000503487.1|ensembl:ENSP00000503513.1|ensembl:ENSP00000503578.1|ensembl:ENSP00000503608.1|ensembl:ENSP00000503652.1|ensembl:ENSP00000503674.1|ensembl:ENSP00000503858.1|ensembl:ENSP00000503909.1|ensembl:ENSP00000504161.1|ensembl:ENSP00000504226.1|ensembl:ENSP00000504336.1|ensembl:ENSP00000504480.1|ensembl:ENSP00000504638.1|ensembl:ENSP00000504659.1|ensembl:ENSP00000504797.1|ensembl:ENSP00000518417.1|ensembl:ENSP00000518418.1|ensembl:ENSP00000518419.1|ensembl:ENSP00000518420.1|ensembl:ENSP00000518421.1|ensembl:ENSP00000518426.1|ensembl:ENSP00000518427.1|ensembl:ENSP00000518428.1|ensembl:ENSP00000518429.1|ensembl:ENSP00000518430.1|ensembl:ENSP00000518431.1|ensembl:ENSP00000518432.1|ensembl:ENSP00000518433.1|ensembl:ENSP00000518434.1|ensembl:ENSP00000518435.1|ensembl:ENSP00000518436.1|ensembl:ENSP00000518437.1|ensembl:ENSP00000518438.1|ensembl:ENSP00000518440.1|ensembl:ENSP00000518441.1|ensembl:ENSP00000518442.1|ensembl:ENSP00000518443.1|ensembl:ENSP00000518444.1|ensembl:ENSP00000518445.1|ensembl:ENSP00000518448.1|ensembl:ENSP00000518449.1|ensembl:ENSP00000518450.1|ensembl:ENSP00000518452.1|ensembl:ENSP00000518455.1|ensembl:ENSP00000518456.1|ensembl:ENSP00000518457.1|ensembl:ENSP00000518460.1|ensembl:ENSP00000518464.1|ensembl:ENSP00000518466.1|ensembl:ENSP00000518468.1|ensembl:ENSP00000518469.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874350|imex:IM-13779-8150	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164733.23(gene)|ensembl:ENSG00000285132.3(gene)|ensembl:ENST00000345125.8(transcript)|ensembl:ENST00000353047.11(transcript)|ensembl:ENST00000526645.6(transcript)|ensembl:ENST00000527215.7(transcript)|ensembl:ENST00000527243.6(transcript)|ensembl:ENST00000528965.3(transcript)|ensembl:ENST00000530296.6(transcript)|ensembl:ENST00000530640.7(transcript)|ensembl:ENST00000531089.6(transcript)|ensembl:ENST00000531502.6(transcript)|ensembl:ENST00000532392.3(transcript)|ensembl:ENST00000532656.7(transcript)|ensembl:ENST00000533455.6(transcript)|ensembl:ENST00000534382.6(transcript)|ensembl:ENST00000534510.6(transcript)|ensembl:ENST00000646105.3(transcript)|ensembl:ENST00000646239.2(transcript)|ensembl:ENST00000676691.1(transcript)|ensembl:ENST00000676755.1(transcript)|ensembl:ENST00000676825.1(transcript)|ensembl:ENST00000676843.1(transcript)|ensembl:ENST00000676952.1(transcript)|ensembl:ENST00000677082.1(transcript)|ensembl:ENST00000677366.1(transcript)|ensembl:ENST00000677415.1(transcript)|ensembl:ENST00000677418.1(transcript)|ensembl:ENST00000677544.1(transcript)|ensembl:ENST00000677650.1(transcript)|ensembl:ENST00000677671.1(transcript)|ensembl:ENST00000677819.1(transcript)|ensembl:ENST00000677873.1(transcript)|ensembl:ENST00000678092.1(transcript)|ensembl:ENST00000678145.1(transcript)|ensembl:ENST00000678242.1(transcript)|ensembl:ENST00000678357.1(transcript)|ensembl:ENST00000678615.1(transcript)|ensembl:ENST00000678929.1(transcript)|ensembl:ENST00000679051.1(transcript)|ensembl:ENST00000679128.1(transcript)|ensembl:ENST00000679140.1(transcript)|ensembl:ENST00000710700.1(transcript)|ensembl:ENST00000710702.1(transcript)|ensembl:ENST00000710703.1(transcript)|ensembl:ENST00000710704.1(transcript)|ensembl:ENST00000710705.1(transcript)|ensembl:ENST00000710713.1(transcript)|ensembl:ENST00000710714.1(transcript)|ensembl:ENST00000710715.1(transcript)|ensembl:ENST00000710716.1(transcript)|ensembl:ENST00000710717.1(transcript)|ensembl:ENST00000710718.1(transcript)|ensembl:ENST00000710719.1(transcript)|ensembl:ENST00000710720.1(transcript)|ensembl:ENST00000710721.1(transcript)|ensembl:ENST00000710722.1(transcript)|ensembl:ENST00000710723.1(transcript)|ensembl:ENST00000710724.1(transcript)|ensembl:ENST00000710725.1(transcript)|ensembl:ENST00000710727.1(transcript)|ensembl:ENST00000710728.1(transcript)|ensembl:ENST00000710729.1(transcript)|ensembl:ENST00000710730.1(transcript)|ensembl:ENST00000710731.1(transcript)|ensembl:ENST00000710732.1(transcript)|ensembl:ENST00000710743.1(transcript)|ensembl:ENST00000710744.1(transcript)|ensembl:ENST00000710745.1(transcript)|ensembl:ENST00000710747.1(transcript)|ensembl:ENST00000710750.1(transcript)|ensembl:ENST00000710751.1(transcript)|ensembl:ENST00000710752.1(transcript)|ensembl:ENST00000710755.1(transcript)|ensembl:ENST00000710759.1(transcript)|ensembl:ENST00000710761.1(transcript)|ensembl:ENST00000710763.1(transcript)|ensembl:ENST00000710764.1(transcript)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0006508""(proteolysis)|go:""GO:0006590""(thyroid hormone generation)|go:""GO:0008233""(peptidase activity)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030574""(collagen catabolic process)|rcsb pdb:1CSB|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0036021""(endolysosome lumen)|go:""GO:0042470""(melanosome)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0046697""(decidualization)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097067""(cellular response to thyroid hormone stimulus)|go:""GO:1904090""(peptidase inhibitor complex)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|rcsb pdb:8B4T|rcsb pdb:8B5F|rcsb pdb:8HE9|rcsb pdb:8HEI|rcsb pdb:8HEN|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_006716307.1|refseq:XP_006716308.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|dip:DIP-42785N|efo:""Orphanet:50943""|panther:PTHR12411(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:F7584127D460B8F5|rigid:YczpZTZPLTOJ/M42r3f9RTa4f7k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04040	uniprotkb:Q8D092	intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052.4	intact:EBI-2845361	psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short)	psi-mi:q8d092_yerpe(display_long)|uniprotkb:fcuA(gene name)|psi-mi:fcuA(display_short)|uniprotkb:y2556(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874371|imex:IM-13779-8147	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000121691.7(gene)|ensembl:ENST00000241052.5(transcript)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001657""(ureteric bud development)|go:""GO:0001666""(response to hypoxia)|go:""GO:0004046""(aminoacylase activity)|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0009060""(aerobic respiration)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009642""(response to light intensity)|go:""GO:0009650""(UV protection)|go:""GO:0010193""(response to ozone)|go:""GO:0010288""(response to lead ion)|go:""GO:0014823""(response to activity)|go:""GO:0014854""(response to inactivity)|go:""GO:0016020""(membrane)|go:""GO:0016209""(antioxidant activity)|go:""GO:0016684""(oxidoreductase activity, acting on peroxide as acceptor)|go:""GO:0019899""(enzyme binding)|go:""GO:0020027""(hemoglobin metabolic process)|go:""GO:0020037""(heme binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032868""(response to insulin)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033189""(response to vitamin A)|go:""GO:0033197""(response to vitamin E)|go:""GO:0033591""(response to L-ascorbic acid)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045471""(response to ethanol)|go:""GO:0046686""(response to cadmium ion)|go:""GO:0046872""(metal ion binding)|go:""GO:0050661""(NADP binding)|go:""GO:0051781""(positive regulation of cell division)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0062151""(catalase complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070542""(response to fatty acid)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072722""(response to amitrole)|go:""GO:0080184""(response to phenylpropanoid)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|rcsb pdb:7P8W|rcsb pdb:7VD9|rcsb pdb:8EL9|rcsb pdb:8HID|rcsb pdb:8PVD|rcsb pdb:8SGV|rcsb pdb:8WZH|rcsb pdb:8WZJ|rcsb pdb:8WZK|rcsb pdb:8WZM|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017|reactome:R-HSA-9841251|refseq:NP_001743.1|efo:""Orphanet:926""|panther:PTHR11465(orthology-group)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR010105(TonB-dependent siderophore receptor)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606	rogid:7oNsiLRBKD+1PyrMueBNpf/zdLs632	intact-crc:F958ECA02CC94ADE|rigid:PCZJYdYY+7C7UK+6rpr6O8acJBs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P29466	uniprotkb:A0A2U2GXV0	intact:EBI-516667|uniprotkb:B5MDZ1|uniprotkb:Q53EY6|uniprotkb:Q6DMQ1|uniprotkb:Q6GSS3|uniprotkb:Q6PI75|uniprotkb:Q9UCN3|ensembl:ENSP00000410076.3|ensembl:ENSP00000433138.1	intact:EBI-2840495|uniprotkb:Q74PJ9|uniprotkb:A0A0H2W8W4|uniprotkb:A0A384L2Q0|uniprotkb:Q7CL55	psi-mi:casp1_human(display_long)|uniprotkb:Interleukin-1 beta convertase(gene name synonym)|uniprotkb:Interleukin-1 beta-converting enzyme(gene name synonym)|uniprotkb:p45(gene name synonym)|uniprotkb:CASP1(gene name)|psi-mi:CASP1(display_short)|uniprotkb:IL1BC(gene name synonym)|uniprotkb:IL1BCE(gene name synonym)	psi-mi:a0a2u2gxv0_yerpe(display_long)|uniprotkb:YPO3641(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874399|imex:IM-13779-8152	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001214.1|refseq:NP_150634.1|refseq:NP_150635.1|refseq:NP_150636.1|refseq:NP_150637.1|refseq:NP_001244047.1|refseq:NP_001244048.1|ensembl:ENSG00000137752.25(gene)|ensembl:ENST00000436863.7(transcript)|ensembl:ENST00000533400.6(transcript)|go:""GO:0002221""(pattern recognition receptor signaling pathway)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007231""(osmosensory signaling pathway)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0019900""(kinase binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032741""(positive regulation of interleukin-18 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0046456""(icosanoid biosynthetic process)|go:""GO:0050700""(CARD domain binding)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051604""(protein maturation)|go:""GO:0051607""(defense response to virus)|go:""GO:0061702""(canonical inflammasome complex)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072557""(IPAF inflammasome complex)|go:""GO:0072558""(NLRP1 inflammasome complex)|go:""GO:0072559""(NLRP3 inflammasome complex)|go:""GO:0089720""(caspase binding)|go:""GO:0097169""(AIM2 inflammasome complex)|go:""GO:0097179""(protease inhibitor complex)|go:""GO:0140447""(cytokine precursor processing)|go:""GO:0140448""(signaling receptor ligand precursor processing)|go:""GO:0140970""(AIM2 inflammasome complex assembly)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR011600(Peptidase C14, caspase catalytic)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|mint:P29466|rcsb pdb:1BMQ|rcsb pdb:1IBC|rcsb pdb:1ICE|rcsb pdb:1RWK|rcsb pdb:1RWM|rcsb pdb:1RWN|rcsb pdb:1RWO|rcsb pdb:1RWP|rcsb pdb:1RWV|rcsb pdb:1RWW|rcsb pdb:1RWX|rcsb pdb:1SC1|rcsb pdb:1SC3|rcsb pdb:1SC4|rcsb pdb:2FQQ|rcsb pdb:2H48|rcsb pdb:2H4W|rcsb pdb:2H4Y|rcsb pdb:2H51|rcsb pdb:2H54|rcsb pdb:2HBQ|rcsb pdb:2HBR|rcsb pdb:2HBY|rcsb pdb:2HBZ|rcsb pdb:3D6F|rcsb pdb:3D6H|rcsb pdb:3D6M|rcsb pdb:3E4C|rcsb pdb:3NS7|rcsb pdb:5FNA|rcsb pdb:5MMV|rcsb pdb:5MTK|rcsb pdb:6BZ9|rcsb pdb:6F6R|rcsb pdb:6KN0|rcsb pdb:6PZP|rcsb pdb:6VIE|rcsb pdb:7KEU|rcsb pdb:8SV1|rcsb pdb:8WRA|reactome:R-HSA-168638|reactome:R-HSA-448706|reactome:R-HSA-5620971|reactome:R-HSA-6803207|reactome:R-HSA-844456|reactome:R-HSA-844615|reactome:R-HSA-844623|reactome:R-HSA-9008059|reactome:R-HSA-9660826|reactome:R-HSA-9692916|dip:DIP-175N|panther:PTHR47901(orthology-group)"	refseq:WP_002210051.1|refseq:YP_002348526.1|interpro:IPR036869	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/22	rogid:fNWee65mDN6re+Zks1Z1WAbwZL89606	rogid:SVf+9kCFQwgDlka34vEDmNYw9/Q632	intact-crc:2F801B6CF68409F9|rigid:Igtf/1PckmTl8sDhurTfM1Hg20M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14790	uniprotkb:A0A384KHP8	intact:EBI-78060|uniprotkb:Q14793|uniprotkb:Q14794|uniprotkb:Q14795|uniprotkb:Q14796|uniprotkb:Q15780|uniprotkb:Q15806|uniprotkb:Q53TT5|uniprotkb:Q8TDI1|uniprotkb:Q8TDI2|uniprotkb:Q8TDI3|uniprotkb:Q8TDI4|uniprotkb:Q8TDI5|uniprotkb:Q96T22|uniprotkb:Q9C0K4|uniprotkb:O14676|uniprotkb:Q14791|uniprotkb:Q14792|uniprotkb:Q9UQ81|ensembl:ENSP00000396869.2|ensembl:ENSP00000397528.2|ensembl:ENSP00000412523.2|ensembl:ENSP00000501268.1|ensembl:ENSP00000512369.1	intact:EBI-2840740|uniprotkb:Q74S58|uniprotkb:Q0WHX7|uniprotkb:Q7CH24	psi-mi:casp8_human(display_long)|uniprotkb:CASP8(gene name)|psi-mi:CASP8(display_short)|uniprotkb:MCH5(gene name synonym)|uniprotkb:ICE-like apoptotic protease 5(gene name synonym)|uniprotkb:MORT1-associated ced-3 homolog(gene name synonym)|uniprotkb:FADD-homologous ICE/ced-3-like protease(gene name synonym)|uniprotkb:FADD-like ICE(gene name synonym)|uniprotkb:Apoptotic cysteine protease(gene name synonym)|uniprotkb:Apoptotic protease Mch-5(gene name synonym)|uniprotkb:CAP4(gene name synonym)	psi-mi:a0a384khp8_yerpe(display_long)|uniprotkb:cutF(gene name)|psi-mi:cutF(display_short)|uniprotkb:nlpE(gene name synonym)|uniprotkb:YPO1067(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874392|imex:IM-13779-8154	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR10454(orthology-group)|efo:""Orphanet:210159""|efo:""Orphanet:275517""|dip:DIP-30915N|ensembl:ENST00000264275.9|ensembl:ENSP00000264275.5|ensembl:ENST00000323492.11|ensembl:ENSP00000325722.7|ensembl:ENST00000358485.8|ensembl:ENSP00000351273.4|ensembl:ENST00000392258.7|ensembl:ENSP00000376087.3|ensembl:ENST00000392263.6|ensembl:ENSP00000376091.2|ensembl:ENSP00000397528.2|ensembl:ENSP00000412523.2|ensembl:ENSP00000396869.2|ensembl:ENST00000444430.3|ensembl:ENSP00000394434.3|ensembl:ENST00000447616.6|ensembl:ENSP00000388306.2|ensembl:ENSP00000501268.1|ensembl:ENSP00000512369.1|ensembl:ENST00000696068.1|ensembl:ENSP00000512370.1|ensembl:ENST00000696087.1|ensembl:ENSP00000512382.1|ensembl:ENSG00000064012.24(gene)|ensembl:ENST00000413726.6(transcript)|ensembl:ENST00000432109.6(transcript)|ensembl:ENST00000440732.6(transcript)|ensembl:ENST00000673742.1(transcript)|ensembl:ENST00000696067.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006508""(proteolysis)|go:""GO:0006915""(apoptotic process)|go:""GO:0007507""(heart development)|go:""GO:0008233""(peptidase activity)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0030027""(lamellipodium)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032025""(response to cobalt ion)|go:""GO:0032355""(response to estradiol)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032991""(protein-containing complex)|rcsb pdb:1QDU|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042110""(T cell activation)|go:""GO:0042113""(B cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045088""(regulation of innate immune response)|go:""GO:0045471""(response to ethanol)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|go:""GO:0051604""(protein maturation)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0060715""(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097264""(self proteolysis)|go:""GO:0097342""(ripoptosome)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001875(Death effector)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR011029(DEATH-like)|interpro:IPR011600(Peptidase C14, caspase catalytic)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033170|mint:Q14790|rcsb pdb:1F9E|rcsb pdb:1I4E|rcsb pdb:1QTN|rcsb pdb:2C2Z|rcsb pdb:2FUN|rcsb pdb:2K7Z|rcsb pdb:2Y1L|rcsb pdb:3H11|rcsb pdb:3KJN|rcsb pdb:3KJQ|rcsb pdb:4JJ7|rcsb pdb:4PRZ|rcsb pdb:4PS1|rcsb pdb:4ZBW|rcsb pdb:5H31|rcsb pdb:5H33|rcsb pdb:5JQE|rcsb pdb:5L08|rcsb pdb:6AGW|rcsb pdb:6PX9|rcsb pdb:7DEE|rcsb pdb:7LVJ|rcsb pdb:7LVM|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-111465|reactome:R-HSA-140534|reactome:R-HSA-168638|reactome:R-HSA-2562578|reactome:R-HSA-264870|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5660668|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75108|reactome:R-HSA-75153|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9686347|reactome:R-HSA-9693928|reactome:R-HSA-9758274|refseq:NP_001073593.1|refseq:NP_001073594.1|refseq:NP_001219.2|refseq:NP_203519.1|refseq:NP_203520.1|refseq:NP_203522.1|refseq:XP_005246943.1|refseq:XP_005246944.1|refseq:XP_005246945.1|refseq:XP_005246946.1|refseq:XP_005246947.1|refseq:XP_005246948.1|refseq:XP_005246949.1|refseq:XP_006712852.1|refseq:XP_006712853.1|refseq:XP_006712856.1"	interpro:IPR007298(Copper resistance lipoprotein NlpE)|interpro:IPR033450|interpro:IPR038139|interpro:IPR043176|refseq:YP_002346111.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XKI9lMiIKZTtoY2lN/QIm1yTksY9606	rogid:ryLPtdXQoNwxiqxUzYaySoAkJkc632	intact-crc:956B01842CA40D51|rigid:C0vbF7qgU/KZULLf7Y66VQAEecc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04040	uniprotkb:Q8ZIG9	intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052.4	intact:EBI-2841314|uniprotkb:Q0WJD4	psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short)	psi-mi:leu3_yerpe(display_long)|uniprotkb:leuB(gene name)|psi-mi:leuB(display_short)|uniprotkb:3-IPM-DH(gene name synonym)|uniprotkb:Beta-IPM dehydrogenase(gene name synonym)|uniprotkb:YPO0532(locus name)|uniprotkb:y3646(locus name)|uniprotkb:YP_3650(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874385|imex:IM-13779-8151	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000121691.7(gene)|ensembl:ENST00000241052.5(transcript)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001657""(ureteric bud development)|go:""GO:0001666""(response to hypoxia)|go:""GO:0004046""(aminoacylase activity)|go:""GO:0004096""(catalase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0009060""(aerobic respiration)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009642""(response to light intensity)|go:""GO:0009650""(UV protection)|go:""GO:0010193""(response to ozone)|go:""GO:0010288""(response to lead ion)|go:""GO:0014823""(response to activity)|go:""GO:0014854""(response to inactivity)|go:""GO:0016020""(membrane)|go:""GO:0016209""(antioxidant activity)|go:""GO:0016684""(oxidoreductase activity, acting on peroxide as acceptor)|go:""GO:0019899""(enzyme binding)|go:""GO:0020027""(hemoglobin metabolic process)|go:""GO:0020037""(heme binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032868""(response to insulin)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033189""(response to vitamin A)|go:""GO:0033197""(response to vitamin E)|go:""GO:0033591""(response to L-ascorbic acid)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045471""(response to ethanol)|go:""GO:0046686""(response to cadmium ion)|go:""GO:0046872""(metal ion binding)|go:""GO:0050661""(NADP binding)|go:""GO:0051781""(positive regulation of cell division)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0061692""(cellular detoxification of hydrogen peroxide)|go:""GO:0062151""(catalase complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070542""(response to fatty acid)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072722""(response to amitrole)|go:""GO:0080184""(response to phenylpropanoid)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|rcsb pdb:7P8W|rcsb pdb:7VD9|rcsb pdb:8EL9|rcsb pdb:8HID|rcsb pdb:8PVD|rcsb pdb:8SGV|rcsb pdb:8WZH|rcsb pdb:8WZJ|rcsb pdb:8WZK|rcsb pdb:8WZM|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017|reactome:R-HSA-9841251|refseq:NP_001743.1|efo:""Orphanet:926""|panther:PTHR11465(orthology-group)"	"interpro:IPR019818|interpro:IPR024084|interpro:IPR004429(3-isopropylmalate dehydrogenase)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003862""(3-isopropylmalate dehydrogenase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0051287""(NAD binding)|refseq:WP_002210454.1|panther:PTHR42979(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606	rogid:reEfvgdNZvA05yp9jIBUEmyL2/o632	intact-crc:4072B61E2EDA7D02|rigid:pXbPzQJGEzQKFJkPL6hx9Jjp+2A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14511	uniprotkb:A0A5P8YLE8	intact:EBI-2108053|uniprotkb:Q5T9R4|uniprotkb:A8K9G7|uniprotkb:G5E9Y9|uniprotkb:A8MSJ9|uniprotkb:Q5XKI0|ensembl:ENSP00000368759.5|intact:EBI-28980032	intact:EBI-2841627|uniprotkb:Q74Y48|uniprotkb:A0A384L7I3|uniprotkb:A0A0H2W0Y8|uniprotkb:Q7CFX4	psi-mi:casl_human(display_long)|uniprotkb:NEDD9(gene name)|psi-mi:NEDD9(display_short)|uniprotkb:CASL(gene name synonym)|uniprotkb:CRK-associated substrate-related protein(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 9(gene name synonym)|uniprotkb:Cas scaffolding protein family member 2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-12(gene name synonym)	psi-mi:a0a5p8yle8_yerpe(display_long)|uniprotkb:malQ(gene name)|psi-mi:malQ(display_short)|uniprotkb:Amylomaltase(gene name synonym)|uniprotkb:Disproportionating enzyme(gene name synonym)|uniprotkb:YPO0126(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874413|imex:IM-13779-8155	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006394.1|refseq:NP_892011.2|refseq:NP_001135865.1|refseq:NP_001257962.1|panther:PTHR10654(orthology-group)|ensembl:ENSG00000111859.17(gene)|ensembl:ENST00000379446.10(transcript)|go:""GO:0000922""(spindle pole)|go:""GO:0001772""(immunological synapse)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007611""(learning or memory)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030027""(lamellipodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0036064""(ciliary basal body)|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051301""(cell division)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0061523""(cilium disassembly)|go:""GO:0072686""(mitotic spindle)|go:""GO:0097021""(lymphocyte migration into lymphoid organs)|go:""GO:0140131""(positive regulation of lymphocyte chemotaxis)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902952""(positive regulation of dendritic spine maintenance)|go:""GO:1903829""(positive regulation of protein localization)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000522""(positive regulation of immunological synapse formation)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR035746|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:Q14511|rcsb pdb:2L81|rcsb pdb:5X3S"	"interpro:IPR003385(Glycoside hydrolase, family 77)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR048458|go:""GO:0004134""(4-alpha-glucanotransferase activity)|go:""GO:0005975""(carbohydrate metabolic process)|refseq:YP_002345212.1|refseq:WP_002208925.1|panther:PTHR32438(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3PsYJXDgAihLYOOwKMBtDhQZQkU9606	rogid:JdI4fLE1gbtuqHycNtXRKKfEZ7Y632	intact-crc:18F84C7A8723FD6D|rigid:9evwnFEprKGUgWgq4tVC5CVU/UU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14511	uniprotkb:A0A2U2GX99	intact:EBI-2108053|uniprotkb:Q5T9R4|uniprotkb:A8K9G7|uniprotkb:G5E9Y9|uniprotkb:A8MSJ9|uniprotkb:Q5XKI0|ensembl:ENSP00000368759.5|intact:EBI-28980032	intact:EBI-2854330|uniprotkb:Q0WIX6|uniprotkb:Q7CGJ4|uniprotkb:A0A384L6K3	psi-mi:casl_human(display_long)|uniprotkb:NEDD9(gene name)|psi-mi:NEDD9(display_short)|uniprotkb:CASL(gene name synonym)|uniprotkb:CRK-associated substrate-related protein(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 9(gene name synonym)|uniprotkb:Cas scaffolding protein family member 2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-12(gene name synonym)	psi-mi:a0a2u2gx99_yerpe(display_long)|uniprotkb:YPO0698(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874406|imex:IM-13779-8153	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006394.1|refseq:NP_892011.2|refseq:NP_001135865.1|refseq:NP_001257962.1|panther:PTHR10654(orthology-group)|ensembl:ENSG00000111859.17(gene)|ensembl:ENST00000379446.10(transcript)|go:""GO:0000922""(spindle pole)|go:""GO:0001772""(immunological synapse)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007611""(learning or memory)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0030027""(lamellipodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0036064""(ciliary basal body)|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051301""(cell division)|go:""GO:0061098""(positive regulation of protein tyrosine kinase activity)|go:""GO:0061523""(cilium disassembly)|go:""GO:0072686""(mitotic spindle)|go:""GO:0097021""(lymphocyte migration into lymphoid organs)|go:""GO:0140131""(positive regulation of lymphocyte chemotaxis)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1902952""(positive regulation of dendritic spine maintenance)|go:""GO:1903829""(positive regulation of protein localization)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000522""(positive regulation of immunological synapse formation)|interpro:IPR001452(Src homology-3)|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR021901|interpro:IPR035746|interpro:IPR036028|interpro:IPR037362|interpro:IPR038319|mint:Q14511|rcsb pdb:2L81|rcsb pdb:5X3S"	"interpro:IPR042186|interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR025885|interpro:IPR025949|refseq:WP_002211458.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR037224|interpro:IPR043142|refseq:YP_002345762.1|panther:PTHR30451(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3PsYJXDgAihLYOOwKMBtDhQZQkU9606	rogid:JVraEv1dK3EeqcZNuRxbt8xrN34632	intact-crc:521DF725F1377DF7|rigid:T3+T5F/Roh1YY2M+ePZbIXolZFk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O68779	uniprotkb:P27797	intact:EBI-2853455|intact:EBI-2855635|uniprotkb:Q74YF2|uniprotkb:Q7ARB0|uniprotkb:Q7BT13|uniprotkb:A0A3G5L6V4|uniprotkb:A0A1U8QYA4|uniprotkb:A0A0H2W5L4|uniprotkb:Q7CIE2	intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866.4|ensembl:ENSP00000466037.2	psi-mi:o68779_yerpe(display_long)|uniprotkb:y1062(gene name)|psi-mi:y1062(display_short)|uniprotkb:ypmt1.80C(gene name synonym)|uniprotkb:ISU59_11670(orf name)|uniprotkb:ISU59_12615(orf name)|uniprotkb:YPMT1.80c(locus name)|uniprotkb:YPO0011(locus name)|uniprotkb:YPO1493(locus name)|uniprotkb:YPO1561(locus name)|uniprotkb:YPO1583(locus name)|uniprotkb:YPO1589(locus name)|uniprotkb:YPO1621(locus name)|uniprotkb:YPO1727(locus name)|uniprotkb:YPO1988(locus name)|uniprotkb:YPO2104(locus name)|uniprotkb:YPO2136(locus name)|uniprotkb:YPO2170(locus name)|uniprotkb:YPO2194(locus name)|uniprotkb:YPO2447(locus name)|uniprotkb:YPO2571(locus name)|uniprotkb:YPO2656(locus name)|uniprotkb:YPO2783(locus name)|uniprotkb:YPO2799(locus name)|uniprotkb:YPO2862(locus name)|uniprotkb:YPO2942(locus name)|uniprotkb:YPO3875(locus name)	psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874452|imex:IM-13779-8158	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395426.1|refseq:NP_857700.1|interpro:IPR001207(Transposase, mutator type)|refseq:YP_093966.1|refseq:WP_002209743.1|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|refseq:YP_002347531.1|refseq:YP_002345107.1|refseq:YP_002346509.1|refseq:YP_002346575.1|refseq:YP_002346595.1|refseq:YP_002346600.1|refseq:YP_002346632.1|refseq:YP_002346729.1|refseq:YP_002346973.1|refseq:YP_002347085.1|refseq:YP_002347114.1|refseq:YP_002347145.1|refseq:YP_002347167.1|refseq:YP_002347411.1|refseq:YP_002347607.1|refseq:YP_002347730.1|refseq:YP_002347741.1|refseq:YP_002347797.1|refseq:YP_002347869.1|refseq:YP_002348751.1|panther:PTHR33217(orthology-group)"	"ensembl:ENSG00000179218.15(gene)|ensembl:ENST00000316448.10(transcript)|ensembl:ENST00000586967.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001849""(complement component C1q complex binding)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005506""(iron ion binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005925""(focal adhesion)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006457""(protein folding)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0022417""(obsolete protein maturation by protein folding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030866""(cortical actin cytoskeleton organization)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0033018""(sarcoplasmic reticulum lumen)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0033144""(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:""GO:0033574""(response to testosterone)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0036503""(ERAD pathway)|go:""GO:0040020""(regulation of meiotic nuclear division)|go:""GO:0042277""(peptide binding)|go:""GO:0042562""(hormone binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0042921""(nuclear receptor-mediated glucocorticoid signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0044194""(cytolytic granule)|go:""GO:0044322""(endoplasmic reticulum quality control compartment)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048387""(negative regulation of retinoic acid receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051208""(sequestering of calcium ion)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060473""(cortical granule)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071257""(cellular response to electrical stimulus)|go:""GO:0071285""(cellular response to lithium ion)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0090398""(cellular senescence)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0098586""(cellular response to virus)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140313""(molecular sequestering activity)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901164""(negative regulation of trophoblast cell migration)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901652""(response to peptide)|go:""GO:1903416""(response to glycoside)|go:""GO:1904614""(response to biphenyl)|go:""GO:2000510""(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|rcsb pdb:7QPD|rcsb pdb:8TZO|rcsb pdb:8TZR|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|refseq:NP_004334.1|dip:DIP-104N|efo:""Orphanet:131""|efo:""Orphanet:3318""|efo:""Orphanet:824""|panther:PTHR11073(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y/++sl3PEsvjk5YqmX2+hc+8JHM632	rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606	intact-crc:8EAB8FF6A2C34BB8|rigid:KaV1p/whpxIzilSqJffJnSv7KZc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86UW7	uniprotkb:Q8D0S2	intact:EBI-308769|uniprotkb:Q658Q2|uniprotkb:Q7Z5T7|uniprotkb:Q8IZW9|uniprotkb:Q8N7M4|uniprotkb:Q9H6P4|uniprotkb:Q9HCI1|uniprotkb:Q9NWK8|uniprotkb:A4D0X3|uniprotkb:B7ZM56|ensembl:ENSP00000398481.2	intact:EBI-2860250	psi-mi:caps2_human(display_long)|uniprotkb:KIAA1591(gene name synonym)|uniprotkb:CADPS2(gene name)|psi-mi:CADPS2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym)|uniprotkb:CAPS2(gene name synonym)	psi-mi:q8d0s2_yerpe(display_long)|uniprotkb:y1672(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874420|imex:IM-13779-8160	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001009571.2|refseq:NP_001161412.1|refseq:NP_060424.9|ensembl:ENSG00000081803.17(gene)|ensembl:ENST00000449022.7(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0008289""(lipid binding)|go:""GO:0015031""(protein transport)|go:""GO:0016079""(synaptic vesicle exocytosis)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0046872""(metal ion binding)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1990504""(dense core granule exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR033227|interpro:IPR035892|mint:Q86UW7|panther:PTHR12166(orthology-group)"	"interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR050903|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR035965|interpro:IPR013655(PAS fold-3)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:f6jQKWbbAM0fC3mlwTazEbDh8ME9606	rogid:Ijy2z//5zbVT/OTgKSlRqBBFln8632	intact-crc:C2ADD20ED1DD2093|rigid:SNl8cshzOSynJPbIDmKIfdX1xlc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01518	uniprotkb:Q8ZED8	intact:EBI-2808398|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1|ensembl:ENSP00000361878.2|ensembl:ENSP00000361883.3|ensembl:ENSP00000361891.3	intact:EBI-2840186|uniprotkb:Q0WET1	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:rnb_yerpe(display_long)|uniprotkb:rnb(gene name)|psi-mi:rnb(display_short)|uniprotkb:Exoribonuclease II(gene name synonym)|uniprotkb:YPO2235(locus name)|uniprotkb:y2077(locus name)|uniprotkb:YP_2034(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874438|imex:IM-13779-8159	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_005270425.1|ensembl:ENSG00000131236.18(gene)|ensembl:ENST00000372792.7(transcript)|ensembl:ENST00000372797.7(transcript)|ensembl:ENST00000372805.8(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001667""(ameboidal-type cell migration)|go:""GO:0003779""(actin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007015""(actin filament organization)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007165""(signal transduction)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0019933""(cAMP-mediated signaling)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098885""(modification of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR036222|interpro:IPR036223|interpro:IPR053950|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|dip:DIP-62063N|panther:PTHR10652(orthology-group)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR022966|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011804(Ribonuclease II, bacterial)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008859""(exoribonuclease II activity)|refseq:WP_002210605.1|interpro:IPR001900(Ribonuclease II and R)|refseq:YP_002347207.1|interpro:IPR050180|panther:PTHR23355(orthology-group)"	"psi-mi:""MI:0469""(intact)"	crc64:7789D1FAC0D1AB7B	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rogid:8bPsungEsr2YreZsZg9IgHPm9uI632	intact-crc:8E099DE4235957B5|rigid:0lQmM0Zw1wjiFRkBDGD8qf39tJk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49069	uniprotkb:A0A380PL37	intact:EBI-1748958|uniprotkb:A1L3Y3|ensembl:ENSP00000297156.2	intact:EBI-2848428|uniprotkb:Q74PX4|uniprotkb:A0A0H2W7W6|uniprotkb:Q7CG52|uniprotkb:A0A384KFS5	psi-mi:camlg_human(display_long)|uniprotkb:CAMLG(gene name)|psi-mi:CAMLG(display_short)|uniprotkb:CAML(gene name synonym)|uniprotkb:Calcium signal-modulating cyclophilin ligand(gene name synonym)|uniprotkb:GET2(gene name synonym)	psi-mi:a0a380pl37_yerpe(display_long)|uniprotkb:YPO0421(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874445|imex:IM-13779-8157	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001736.1|ensembl:ENSG00000164615.6(gene)|ensembl:ENST00000297156.4(transcript)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001881""(receptor recycling)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006952""(defense response)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0043529""(GET complex)|go:""GO:0045048""(protein insertion into ER membrane)|go:""GO:0050821""(protein stabilization)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016719(Calcium signal-modulating cyclophilin ligand)|mint:P49069|rcsb pdb:6SO5|rcsb pdb:8CR1|reactome:R-HSA-9609523|panther:PTHR15026(orthology-group)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR027463|refseq:WP_002209200.1|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:YP_002345497.1|panther:PTHR32063(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BUKJ1VPumP1iJJnr485rxWzEyK49606	rogid:eNynpfVNIWDaaydEc5eAanQErH8632	intact-crc:6EA08C4AAF77CF4F|rigid:H332MpXFAOA47Fn4DES39JUelOk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86UW7	uniprotkb:A0A6M0NPF2	intact:EBI-308769|uniprotkb:Q658Q2|uniprotkb:Q7Z5T7|uniprotkb:Q8IZW9|uniprotkb:Q8N7M4|uniprotkb:Q9H6P4|uniprotkb:Q9HCI1|uniprotkb:Q9NWK8|uniprotkb:A4D0X3|uniprotkb:B7ZM56|ensembl:ENSP00000398481.2	intact:EBI-2874427	psi-mi:caps2_human(display_long)|uniprotkb:KIAA1591(gene name synonym)|uniprotkb:CADPS2(gene name)|psi-mi:CADPS2(display_short)|uniprotkb:Calcium-dependent activator protein for secretion 2(gene name synonym)|uniprotkb:CAPS2(gene name synonym)	psi-mi:a0a6m0npf2_yerpe(display_long)|uniprotkb:rstB(gene name)|psi-mi:rstB(display_short)|uniprotkb:y2140(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874431|imex:IM-13779-8156	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001009571.2|refseq:NP_001161412.1|refseq:NP_060424.9|ensembl:ENSG00000081803.17(gene)|ensembl:ENST00000449022.7(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005929""(cilium)|go:""GO:0006887""(exocytosis)|go:""GO:0008289""(lipid binding)|go:""GO:0015031""(protein transport)|go:""GO:0016079""(synaptic vesicle exocytosis)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045921""(positive regulation of exocytosis)|go:""GO:0046872""(metal ion binding)|go:""GO:0098793""(presynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1990504""(dense core granule exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR033227|interpro:IPR035892|mint:Q86UW7|panther:PTHR12166(orthology-group)"	"uniprotkb:A0A6B3SXQ0(uniprot-removed-ac)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0016020""(membrane)|interpro:IPR050980|refseq:WP_002232819.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:f6jQKWbbAM0fC3mlwTazEbDh8ME9606	rogid:3WuZUmxz/SJ1dNvTN8+aaCKNTV4632	intact-crc:F155151AF56AA15B|rigid:D0JU2HueAeUDsHga/h4zpLu6OrY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62158	uniprotkb:A0A2U2GX38	intact:EBI-397435|uniprotkb:P02593|uniprotkb:Q53S29|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	intact:EBI-2841288|uniprotkb:A0A0H2W637|uniprotkb:Q74SI0|uniprotkb:A0A384LBC5|uniprotkb:Q7CJG2|uniprotkb:A0A380PEL1	psi-mi:calm_human(display_short)|psi-mi:P62158(display_long)|uniprotkb:CALM1(gene name)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:a0a2u2gx38_yerpe(display_long)|uniprotkb:YPO2999(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874466|imex:IM-13779-8164	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:1304""(molecule set)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:""GO:0002027""(regulation of heart rate)|go:""GO:0005513""(detection of calcium ion)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0030017""(sarcomere)|go:""GO:0030801""(obsolete positive regulation of cyclic nucleotide metabolic process)|go:""GO:0032516""(obsolete positive regulation of phosphoprotein phosphatase activity)|go:""GO:0035307""(obsolete positive regulation of protein dephosphorylation)|go:""GO:0051343""(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005876""(spindle microtubule)|go:""GO:0000922""(spindle pole)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0006936""(muscle contraction)|go:""GO:0060315""(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0002576""(platelet degranulation)|go:""GO:0060316""(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0050999""(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:""GO:0010801""(negative regulation of peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031954""(positive regulation of protein autophosphorylation)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0000165""(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:5COC|go:""GO:0021762""(substantia nigra development)|go:""GO:0070062""(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|rcsb pdb:4GOW|rcsb pdb:4Q57|go:""GO:0043647""(inositol phosphate metabolic process)|go:""GO:0022400""(regulation of opsin-mediated signaling pathway)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0005576""(extracellular region)|go:""GO:0031997""(obsolete N-terminal myristoylation domain binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0010880""(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031432""(titin binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051592""(response to calcium ion)|go:""GO:0055117""(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:""GO:0005088""|go:""GO:0007223""(Wnt signaling pathway, calcium modulating pathway)|go:""GO:0008440""(inositol-1,4,5-trisphosphate 3-kinase activity)|go:""GO:0015276""(ligand-gated monoatomic ion channel activity)|go:""GO:0005634""(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:4UMO|rcsb pdb:4V0C|go:""GO:0031982""(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|refseq:NP_001292555.1|rcsb pdb:4OVN|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|rcsb pdb:5DBR|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0001975""(response to amphetamine)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0030235""(nitric-oxide synthase regulator activity)|go:""GO:0030426""(growth cone)|go:""GO:0051000""(positive regulation of nitric-oxide synthase activity)|go:""GO:0051412""(response to corticosterone)|go:""GO:1901841""(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:""GO:0032991""(protein-containing complex)|go:""GO:0006479""(protein methylation)|go:""GO:0014069""(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0043388""(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:""GO:0034704""(calcium channel complex)|go:""GO:0010856""(adenylate cyclase activator activity)|go:""GO:0051186""(obsolete cofactor metabolic process)|go:""GO:0075206""(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:""GO:0060314""(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:""GO:1902494""(catalytic complex)|go:""GO:0043234""|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0030819""(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:""GO:0019722""(calcium-mediated signaling)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:""GO:0005623""(obsolete cell)|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|rcsb pdb:6HR1|rcsb pdb:6OS4|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0016032""(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O"	"interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|refseq:YP_002347923.1|go:""GO:0019898""(extrinsic component of membrane)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0030313""(cell envelope)|go:""GO:1990195""(macrolide transmembrane transporter complex)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|refseq:WP_002208495.1|interpro:IPR030190"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	-	rogid:sdWXUSDDDoa4ne7FHbQ56e9RFP4632	intact-crc:C43E2A93CB621641	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43155	uniprotkb:Q7CIG9	intact:EBI-2843568|uniprotkb:Q5T952|uniprotkb:Q9BW16|ensembl:ENSP00000315013.2	intact:EBI-2840661|uniprotkb:Q74U07	psi-mi:cacp_human(display_long)|uniprotkb:CRAT(gene name)|psi-mi:CRAT(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:Carnitine acetyltransferase(gene name synonym)	psi-mi:q7cig9_yerpe(display_long)|uniprotkb:YPO2151(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874480|imex:IM-13779-8163	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005251765.1|ensembl:ENSG00000095321.18(gene)|ensembl:ENST00000318080.7(transcript)|go:""GO:0003997""(acyl-CoA oxidase activity)|go:""GO:0004092""(carnitine O-acetyltransferase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0008458""(carnitine O-octanoyltransferase activity)|go:""GO:0019254""(carnitine metabolic process, CoA-linked)|go:""GO:0033540""(fatty acid beta-oxidation using acyl-CoA oxidase)|go:""GO:0046459""(short-chain fatty acid metabolic process)|go:""GO:0051791""(medium-chain fatty acid metabolic process)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042231|rcsb pdb:1NM8|rcsb pdb:1S5O|reactome:R-HSA-389887|reactome:R-HSA-9033241|panther:PTHR22589(orthology-group)"	"interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|go:""GO:0016020""(membrane)|refseq:YP_002347127.1|interpro:IPR050638|panther:PTHR42920(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8RNAVz4LO74SbC/vjUy8iMVnTwM9606	rogid:JuykHGpRd9P5/XN7ebYt6IqDuS0632	intact-crc:97828AA1CD387826|rigid:A0QHYN6G+5h+QN9km4YPY8AeOHY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P22223	uniprotkb:Q7ARD3	intact:EBI-2837250|uniprotkb:Q05DI6|uniprotkb:B2R6F4|ensembl:ENSP00000264012.4|intact:EBI-28986946	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:cadh3_human(display_long)|uniprotkb:CDH3(gene name)|psi-mi:CDH3(display_short)|uniprotkb:CDHP(gene name synonym)|uniprotkb:Placental cadherin(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874473|imex:IM-13779-8162	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000062038.15(gene)|ensembl:ENST00000264012.9(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001895""(retina homeostasis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007601""(visual perception)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010838""(positive regulation of keratinocyte proliferation)|go:""GO:0016339""(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0016342""(catenin complex)|go:""GO:0016477""(cell migration)|go:""GO:0022405""(hair cycle process)|go:""GO:0030054""(cell junction)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031424""(keratinization)|go:""GO:0032773""(positive regulation of tyrosinase activity)|go:""GO:0034332""(adherens junction organization)|go:""GO:0043568""(positive regulation of insulin-like growth factor receptor signaling pathway)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045296""(cadherin binding)|go:""GO:0048023""(positive regulation of melanin biosynthetic process)|go:""GO:0051796""(negative regulation of timing of catagen)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:1902910""(positive regulation of melanosome transport)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|mint:P22223|rcsb pdb:4OY9|rcsb pdb:4ZML|rcsb pdb:4ZMN|rcsb pdb:4ZMO|rcsb pdb:4ZMP|rcsb pdb:4ZMQ|rcsb pdb:4ZMT|rcsb pdb:4ZMV|rcsb pdb:4ZMW|rcsb pdb:4ZMX|rcsb pdb:4ZMY|rcsb pdb:4ZMZ|rcsb pdb:5JYL|rcsb pdb:5JYM|rcsb pdb:6ZTB|rcsb pdb:6ZTR|rcsb pdb:7CME|rcsb pdb:7CMF|rcsb pdb:8HYI|reactome:R-HSA-418990|refseq:NP_001304124.1|refseq:NP_001304125.1|refseq:NP_001784.2|efo:""Orphanet:1573""|efo:""Orphanet:1897""|panther:PTHR24027(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:emdhHH/ZoZW6BYmtu0u/0ytqh789606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:CF109A9B969A112E|rigid:S36AfaWq4/gFsa7IZCB1ZL5f1qo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62158	uniprotkb:P17778	intact:EBI-397435|uniprotkb:P02593|uniprotkb:Q53S29|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	intact:EBI-2842665|uniprotkb:O68701	psi-mi:calm_human(display_short)|psi-mi:P62158(display_long)|uniprotkb:CALM1(gene name)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874459|imex:IM-13779-8161	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:1304""(molecule set)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:""GO:0010800""(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:""GO:0002027""(regulation of heart rate)|go:""GO:0005513""(detection of calcium ion)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0030017""(sarcomere)|go:""GO:0030801""(obsolete positive regulation of cyclic nucleotide metabolic process)|go:""GO:0032516""(obsolete positive regulation of phosphoprotein phosphatase activity)|go:""GO:0035307""(obsolete positive regulation of protein dephosphorylation)|go:""GO:0051343""(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005876""(spindle microtubule)|go:""GO:0000922""(spindle pole)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0006936""(muscle contraction)|go:""GO:0060315""(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0002576""(platelet degranulation)|go:""GO:0060316""(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0050999""(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:""GO:0010801""(negative regulation of peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031954""(positive regulation of protein autophosphorylation)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0000165""(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:5COC|go:""GO:0021762""(substantia nigra development)|go:""GO:0070062""(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|rcsb pdb:4GOW|rcsb pdb:4Q57|go:""GO:0043647""(inositol phosphate metabolic process)|go:""GO:0022400""(regulation of opsin-mediated signaling pathway)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0005576""(extracellular region)|go:""GO:0031997""(obsolete N-terminal myristoylation domain binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0010880""(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031432""(titin binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051592""(response to calcium ion)|go:""GO:0055117""(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:""GO:0005088""|go:""GO:0007223""(Wnt signaling pathway, calcium modulating pathway)|go:""GO:0008440""(inositol-1,4,5-trisphosphate 3-kinase activity)|go:""GO:0015276""(ligand-gated monoatomic ion channel activity)|go:""GO:0005634""(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:4UMO|rcsb pdb:4V0C|go:""GO:0031982""(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|refseq:NP_001292555.1|rcsb pdb:4OVN|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|rcsb pdb:5DBR|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0001975""(response to amphetamine)|go:""GO:0007190""(activation of adenylate cyclase activity)|go:""GO:0030235""(nitric-oxide synthase regulator activity)|go:""GO:0030426""(growth cone)|go:""GO:0051000""(positive regulation of nitric-oxide synthase activity)|go:""GO:0051412""(response to corticosterone)|go:""GO:1901841""(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:""GO:0032991""(protein-containing complex)|go:""GO:0006479""(protein methylation)|go:""GO:0014069""(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0043388""(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:""GO:0034704""(calcium channel complex)|go:""GO:0010856""(adenylate cyclase activator activity)|go:""GO:0051186""(obsolete cofactor metabolic process)|go:""GO:0075206""(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:""GO:0060314""(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:""GO:1902494""(catalytic complex)|go:""GO:0043234""|go:""GO:0008179""(adenylate cyclase binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0030819""(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:""GO:0019722""(calcium-mediated signaling)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:""GO:0005623""(obsolete cell)|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|rcsb pdb:6HR1|rcsb pdb:6OS4|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0016032""(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	-	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:E7E2BAC826735D02	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WKQ4	uniprotkb:Q9P1Z2	intact:EBI-2841918|uniprotkb:Q74YB1|uniprotkb:Q7CLB1|uniprotkb:A0A5P8YL50|uniprotkb:A0A0H2W0T4	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960.1	psi-mi:q0wkq4_yerpe(display_long)|uniprotkb:spoT(gene name)|psi-mi:spoT(display_short)|uniprotkb:YPO0038(locus name)	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874487|imex:IM-13779-8165	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR007685(RelA/SpoT)|interpro:IPR004811(RelA/SpoT protein)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR033655|go:""GO:0015970""(guanosine tetraphosphate biosynthetic process)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002209002.1|interpro:IPR043519|refseq:YP_002345134.1|interpro:IPR045600|interpro:IPR045865"	"refseq:NP_001137154.1|refseq:NP_065949.1|ensembl:ENSG00000012822.16(gene)|ensembl:ENST00000550804.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030518""(nuclear receptor-mediated steroid hormone signaling pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|interpro:IPR051002|mint:Q9P1Z2|refseq:XP_016875196.1|dip:DIP-47322N|panther:PTHR31915(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DFSylU3fdvQugjKDCGmQic4raK0632	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	intact-crc:2F782EEFE9848B6B|rigid:7PaCOfwhiODMMykgtigWAKzOsOk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YHK6	uniprotkb:Q9P1Z2	intact:EBI-2856093|uniprotkb:A0A0H2W5D6|uniprotkb:Q74SI7|uniprotkb:Q7CJF5|uniprotkb:A0A384KU48	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960.1	psi-mi:a0a5p8yhk6_yerpe(display_long)|uniprotkb:cysK(gene name)|psi-mi:cysK(display_short)|uniprotkb:cysZ(gene name synonym)|uniprotkb:YPO2992(locus name)	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874494|imex:IM-13779-8170	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR005856(Cysteine synthase K/M)|interpro:IPR005859(Cysteine synthase A)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR050214|refseq:WP_002222180.1|go:""GO:0004124""(cysteine synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006535""(cysteine biosynthetic process from serine)|go:""GO:0080146""(L-cysteine desulfhydrase activity)|interpro:IPR036052|refseq:YP_002347916.1|panther:PTHR10314(orthology-group)"	"refseq:NP_001137154.1|refseq:NP_065949.1|ensembl:ENSG00000012822.16(gene)|ensembl:ENST00000550804.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030518""(nuclear receptor-mediated steroid hormone signaling pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|interpro:IPR051002|mint:Q9P1Z2|refseq:XP_016875196.1|dip:DIP-47322N|panther:PTHR31915(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UrC5dh7j9HnS/MZkY6/7kxZcpME632	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	intact-crc:62892BA20F9251D0|rigid:+2d6jQ+6IhTNkXDxBPjOlCKHido	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCK2	uniprotkb:O60840	intact:EBI-2844238|uniprotkb:Q0WCT2	intact:EBI-1757401|uniprotkb:F5CIQ9|uniprotkb:O43901|uniprotkb:A6NI29|uniprotkb:Q9UHB1|uniprotkb:O95226|ensembl:ENSP00000365441.2	psi-mi:mnth_yerpe(display_long)|uniprotkb:mntH(gene name)|psi-mi:mntH(display_short)|uniprotkb:YPO2982(locus name)|uniprotkb:y1500(locus name)|uniprotkb:YP_2607(locus name)	psi-mi:cac1f_human(display_long)|uniprotkb:CACNA1F(gene name)|psi-mi:CACNA1F(display_short)|uniprotkb:CACNAF1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874526|imex:IM-13779-8169	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001046(Natural resistance-associated macrophage protein)|go:""GO:0005384""(manganese ion transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006828""(manganese ion transport)|go:""GO:0015086""(cadmium ion transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|go:""GO:0034755""(iron ion transmembrane transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0071281""(cellular response to iron ion)|refseq:WP_002211621.1|refseq:YP_002347906.1|panther:PTHR11706(orthology-group)"	"efo:""Orphanet:178333""|efo:""Orphanet:1872""|efo:""Orphanet:215""|ensembl:ENSG00000102001.13(gene)|ensembl:ENST00000376265.2(transcript)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0005245""(voltage-gated calcium channel activity)|go:""GO:0005891""(voltage-gated calcium channel complex)|go:""GO:0007601""(visual perception)|go:""GO:0008331""(high voltage-gated calcium channel activity)|go:""GO:0016020""(membrane)|go:""GO:0043204""(perikaryon)|go:""GO:0046872""(metal ion binding)|go:""GO:0050908""(detection of light stimulus involved in visual perception)|go:""GO:0098703""(calcium ion import across plasma membrane)|go:""GO:1901386""(negative regulation of voltage-gated calcium channel activity)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|interpro:IPR050599|refseq:NP_001243718.1|refseq:NP_001243719.1|refseq:NP_005174.2|panther:PTHR45628(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zWKfJk5oio19xxchpmXI9whBTnE632	rogid:39fJ2/IELLpqqllk72X/OwP5hXQ9606	intact-crc:1524C36A00B7C275|rigid:KVkYa6PBPai0/X4cCMjDFPXmujU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKN6	uniprotkb:Q08289	intact:EBI-2855015|uniprotkb:Q74S26	intact:EBI-2874501|uniprotkb:Q5QJ99|uniprotkb:Q5QJA0|uniprotkb:Q6TME1|uniprotkb:Q6TME3|uniprotkb:A6PVM5|uniprotkb:Q5VVH0|uniprotkb:Q9HD32|uniprotkb:O00304|uniprotkb:Q96NZ5|uniprotkb:Q96NZ4|uniprotkb:Q5VVG9|uniprotkb:Q5VWV6|uniprotkb:Q9BWU2|uniprotkb:Q9Y341|uniprotkb:Q8WX81|uniprotkb:A6PVM8|uniprotkb:Q96NZ3|uniprotkb:Q9Y340|uniprotkb:A6PVM7|uniprotkb:Q6TME2|ensembl:ENSP00000320025.8	psi-mi:q8ckn6_yerpe(display_long)|uniprotkb:YP_2833(locus name)|uniprotkb:y3210(locus name)	psi-mi:cacb2_human(display_long)|uniprotkb:CACNB2(gene name)|psi-mi:CACNB2(display_short)|uniprotkb:CACNLB2(gene name synonym)|uniprotkb:MYSB(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)|uniprotkb:Lambert-Eaton myasthenic syndrome antigen B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874519|imex:IM-13779-8166	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|go:""GO:0019867""(outer membrane)|interpro:IPR036709"	"ensembl:ENSG00000165995.24(gene)|ensembl:ENST00000324631.13(transcript)|go:""GO:0005245""(voltage-gated calcium channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005891""(voltage-gated calcium channel complex)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007528""(neuromuscular junction development)|go:""GO:0007601""(visual perception)|go:""GO:0045933""(positive regulation of muscle contraction)|go:""GO:0051015""(actin filament binding)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0070509""(calcium ion import)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0086045""(membrane depolarization during AV node cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0098684""(photoreceptor ribbon synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098912""(membrane depolarization during atrial cardiac muscle cell action potential)|go:""GO:0099626""(voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels)|go:""GO:1901843""(positive regulation of high voltage-gated calcium channel activity)|go:""GO:1904879""(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:""GO:1990454""(L-type voltage-gated calcium channel complex)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005444(Voltage-dependent calcium channel, L-type, beta-2 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035605|interpro:IPR036028|interpro:IPR046937|mint:Q08289|rcsb pdb:8HLP|rcsb pdb:8HMA|rcsb pdb:8HMB|reactome:R-HSA-112308|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|reactome:R-HSA-5576892|reactome:R-HSA-5576893|reactome:R-HSA-9662360|refseq:NP_000715.2|refseq:NP_001316989.1|refseq:NP_963864.1|refseq:NP_963865.2|refseq:NP_963866.2|refseq:NP_963884.2|refseq:NP_963887.2|refseq:NP_963890.2|refseq:NP_963891.1|refseq:XP_011517961.1|efo:""Orphanet:130""|panther:PTHR11824(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1PmyGpcWP3bPwcEODrFtqgYq+a0632	rogid:62aD9Wbg0RTCIwNCGexJvVgKkGE9606	intact-crc:D34ABAEC2FE459DD|rigid:zaSN5ZgEYtx7gPpatBQA5WYvqpE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P69980	uniprotkb:O00555	intact:EBI-2845444|uniprotkb:P42714|uniprotkb:Q663J5|uniprotkb:P40297	intact:EBI-766279|uniprotkb:P78510|uniprotkb:P78511|uniprotkb:Q16290|uniprotkb:Q92690|uniprotkb:Q99790|uniprotkb:Q99791|uniprotkb:Q99792|uniprotkb:Q99793|uniprotkb:Q9UDC4|ensembl:ENSP00000353362.5|uniprotkb:J3KP41|uniprotkb:Q9NS88|intact:EBI-28985658	psi-mi:yscr_yerpe(display_long)|uniprotkb:yscR(gene name)|psi-mi:yscR(display_short)|uniprotkb:YPCD1.44(locus name)|uniprotkb:y5034(locus name)|uniprotkb:y0037(locus name)|uniprotkb:YP_pCD39(locus name)	psi-mi:cac1a_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 4(gene name synonym)|uniprotkb:Brain calcium channel I(gene name synonym)|uniprotkb:CACNA1A(gene name)|psi-mi:CACNA1A(display_short)|uniprotkb:CACH4(gene name synonym)|uniprotkb:CACN3(gene name synonym)|uniprotkb:CACNL1A4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874533|imex:IM-13779-8167	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395178.1|refseq:NP_857738.1|refseq:NP_857933.1|interpro:IPR005838(Type III secretion system inner membrane P protein)|interpro:IPR005773(Yop virulence translocation protein R)|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|refseq:WP_002212947.1|panther:PTHR30587(orthology-group)"	"ensembl:ENSG00000141837.23(gene)|ensembl:ENST00000360228.11(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0005245""(voltage-gated calcium channel activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005891""(voltage-gated calcium channel complex)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0008331""(high voltage-gated calcium channel activity)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0042995""(cell projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0098703""(calcium ion import across plasma membrane)|go:""GO:1904645""(response to amyloid-beta)|go:""GO:1904646""(cellular response to amyloid-beta)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005448(Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR050599|mint:O00555|rcsb pdb:3BXK|rcsb pdb:8X90|rcsb pdb:8X91|rcsb pdb:8X93|reactome:R-HSA-112308|reactome:R-HSA-422356|refseq:NP_000059.3|refseq:NP_001120693.1|refseq:NP_001120694.1|refseq:NP_001167551.1|refseq:NP_075461.2|efo:""Orphanet:2131""|efo:""Orphanet:2382""|efo:""Orphanet:442835""|efo:""Orphanet:569""|efo:""Orphanet:71518""|efo:""Orphanet:97""|efo:""Orphanet:98758""|panther:PTHR45628(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8WQqv7KuV4BZ+uBr2fevGUQFw8E632	rogid:0zgBInaSveIMJzCcuCc46+jv2QY9606	intact-crc:14E8BF9392EBDBE4|rigid:SKhmygOm0x/L3nkMNz3F82MiTGQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q96EX1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-2874543|uniprotkb:Q52LP9|uniprotkb:Q8NCB4|uniprotkb:D3DPR5|uniprotkb:Q49AP7|ensembl:ENSP00000428541.1|ensembl:ENSP00000428585.1|ensembl:ENSP00000428984.1|ensembl:ENSP00000430198.1|ensembl:ENSP00000430285.1	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:sim12_human(display_long)|uniprotkb:SMIM12(gene name)|psi-mi:SMIM12(display_short)|uniprotkb:C1orf212(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874540|imex:IM-13779-8168	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:XP_011538855.1|refseq:XP_011538857.1|refseq:NP_001307190.1|refseq:NP_001158296.1|refseq:NP_001158297.1|refseq:NP_612437.3|refseq:XP_005270460.1|ensembl:ENSG00000163866.9(gene)|ensembl:ENST00000417239.1(transcript)|ensembl:ENST00000423898.1(transcript)|ensembl:ENST00000446026.1(transcript)|ensembl:ENST00000456842.1(transcript)|ensembl:ENST00000521580.3(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0016020""(membrane)|interpro:IPR031933|mint:Q96EX1|refseq:XP_016855655.1|panther:PTHR28599(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:qeuRSIWo2rJvSDDvexjGg07txg89606	intact-crc:9540073DEA5DF616|rigid:JdDIhpt4Ndi7gzgxISv0absaymE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A384KHP8	uniprotkb:Q5VTB9	intact:EBI-2840740|uniprotkb:Q74S58|uniprotkb:Q0WHX7|uniprotkb:Q7CH24	intact:EBI-949963|uniprotkb:B3KPJ3|uniprotkb:Q4KMX2|uniprotkb:Q9NVP6|uniprotkb:B4DLZ9|uniprotkb:E9PCS1|ensembl:ENSP00000347548.2|ensembl:ENSP00000354872.2	psi-mi:a0a384khp8_yerpe(display_long)|uniprotkb:cutF(gene name)|psi-mi:cutF(display_short)|uniprotkb:nlpE(gene name synonym)|uniprotkb:YPO1067(locus name)	psi-mi:rn220_human(display_long)|uniprotkb:C1orf164(gene name synonym)|uniprotkb:RNF220(gene name)|psi-mi:RNF220(display_short)|uniprotkb:RING finger protein 220(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF220(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874560|imex:IM-13779-8173	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR007298(Copper resistance lipoprotein NlpE)|interpro:IPR033450|interpro:IPR038139|interpro:IPR043176|refseq:YP_002346111.1	"refseq:NP_060620.2|refseq:NP_001306885.1|refseq:NP_001306886.1|refseq:XP_016857112.1|refseq:XP_016857113.1|refseq:XP_016857114.1|ensembl:ENSG00000187147.19(gene)|ensembl:ENST00000355387.6(transcript)|ensembl:ENST00000361799.7(transcript)|go:""GO:0003358""(noradrenergic neuron development)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005737""(cytoplasm)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021904""(dorsal/ventral neural tube patterning)|go:""GO:0032991""(protein-containing complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:2000677""(regulation of transcription regulatory region DNA binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031824|interpro:IPR040178|interpro:IPR052443|mint:Q5VTB9|reactome:R-HSA-983168|panther:PTHR13459(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ryLPtdXQoNwxiqxUzYaySoAkJkc632	rogid:++tO9LPa3Hh0vhx5A1fIyv+5Djc9606	intact-crc:D0DD69B09EA4C73D|rigid:tx5GEQVM68GTeD8LDrlmPFpEfXI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W3U3	uniprotkb:Q7Z422	intact:EBI-2859897|uniprotkb:Q74VW2|uniprotkb:A0A384LJQ9|uniprotkb:Q0WD94|uniprotkb:Q7CJX6|uniprotkb:A0A3N4B2U6	intact:EBI-2874567|intact:EBI-28975092|uniprotkb:Q7Z424|uniprotkb:Q9Y403|uniprotkb:A8MXJ2|uniprotkb:Q8TBV3|uniprotkb:Q8IVM2|uniprotkb:C9K0U0|ensembl:ENSP00000383866.4|ensembl:ENSP00000516842.1	psi-mi:a0a0h2w3u3_yerpe(display_long)|uniprotkb:bglB(gene name)|psi-mi:bglB(display_short)|uniprotkb:YPO2803(locus name)	psi-mi:szrd1_human(display_long)|uniprotkb:SZRD1(gene name)|psi-mi:SZRD1(display_short)|uniprotkb:C1orf144(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM18/PM20/PM22(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874583|imex:IM-13779-8172	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002347744.1|interpro:IPR002772(Glycoside hydrolase, family 3, C-terminal)|interpro:IPR001764(Glycoside hydrolase, family 3, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR019800|interpro:IPR026891|interpro:IPR050288|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_002209758.1|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR036881|interpro:IPR036962"	refseq:NP_001108072.1|refseq:NP_001258798.1|ensembl:ENSG00000055070.17(gene)|ensembl:ENSG00000291379.1(gene)|ensembl:ENST00000401088.9(transcript)|ensembl:ENST00000707363.1(transcript)|interpro:IPR024642|interpro:IPR024771|interpro:IPR039228|panther:PTHR31796(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CFSXDKLhXQPL2V/gU2biHJW5N3o632	rogid:+KkcHBIWlfNZ8VZgiDWT80ciGsA9606	intact-crc:DC1E566C0FF1299B|rigid:Y5aRrTfmBwWR0QQ6k5HyhmbHnkY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CJF3	uniprotkb:Q8IYL3	intact:EBI-2846856|uniprotkb:Q74SI9	intact:EBI-715898|uniprotkb:Q5SR20|uniprotkb:Q6NX36|uniprotkb:A8K0C8|uniprotkb:A8MUG9|ensembl:ENSP00000355306.3	"psi-mi:dnlj_yerpe(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:""Polydeoxyribonucleotide synthase [NAD(+)]""(gene name synonym)|uniprotkb:YPO2989(locus name)|uniprotkb:YP_2614(locus name)|uniprotkb:y1492(locus name)"	psi-mi:ca174_human(display_long)|uniprotkb:C1orf174(gene name)|psi-mi:C1orf174(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874553|imex:IM-13779-8171	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033136|interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR004149(Zinc-finger, NAD-dependent DNA ligase C4-type)|refseq:WP_002213368.1|go:""GO:0003677""(DNA binding)|go:""GO:0003911""(""DNA ligase (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006288""(obsolete base-excision repair, DNA ligation)|go:""GO:0046872""(metal ion binding)|interpro:IPR036420|interpro:IPR041663|refseq:YP_002347913.1|panther:PTHR23389(orthology-group)"	"refseq:NP_997239.2|ensembl:ENSG00000198912.12(gene)|ensembl:ENST00000361605.4(transcript)|go:""GO:0005654""(nucleoplasm)|interpro:IPR031530|panther:PTHR28491(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ABzJi1jMOUD1WGHNwTu2zo0ozls632	rogid:sTBk5USK8pzrx1PEcpL9VWgDJL89606	intact-crc:E33ACE049E6A3A6B|rigid:ExxRWSo7MY0Vk5hQd0EVsGAjhnA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YBQ9	uniprotkb:Q7Z422	intact:EBI-2844830|uniprotkb:Q74X93|uniprotkb:A0A0H2W369|uniprotkb:Q7CKK6|uniprotkb:A0A2U2GXX7|uniprotkb:A0A384KXD1	intact:EBI-2874567|intact:EBI-28975092|uniprotkb:Q7Z424|uniprotkb:Q9Y403|uniprotkb:A8MXJ2|uniprotkb:Q8TBV3|uniprotkb:Q8IVM2|uniprotkb:C9K0U0|ensembl:ENSP00000383866.4|ensembl:ENSP00000516842.1	psi-mi:a0a5p8ybq9_yerpe(display_long)|uniprotkb:YPO3526(locus name)	psi-mi:szrd1_human(display_long)|uniprotkb:SZRD1(gene name)|psi-mi:SZRD1(display_short)|uniprotkb:C1orf144(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM18/PM20/PM22(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874576|imex:IM-13779-8174	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR005170(Transporter-associated region)|interpro:IPR044751|go:""GO:0005886""(plasma membrane)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_002210164.1|interpro:IPR036318|refseq:YP_002348415.1|interpro:IPR046342"	refseq:NP_001108072.1|refseq:NP_001258798.1|ensembl:ENSG00000055070.17(gene)|ensembl:ENSG00000291379.1(gene)|ensembl:ENST00000401088.9(transcript)|ensembl:ENST00000707363.1(transcript)|interpro:IPR024642|interpro:IPR024771|interpro:IPR039228|panther:PTHR31796(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JC3IVKKYgEftNqAeJWJ+daHPtRo632	rogid:+KkcHBIWlfNZ8VZgiDWT80ciGsA9606	intact-crc:52129D214277968A|rigid:zYqz5GiDJHpQjpsyz3IOHDDYcXk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5SY80	uniprotkb:A0A3N4B418	intact:EBI-2874593|uniprotkb:Q8IYZ6|uniprotkb:B7Z7X5|uniprotkb:B4DZR4|uniprotkb:E9PEA3|ensembl:ENSP00000355492.4	intact:EBI-2840046|uniprotkb:Q0WFD2|uniprotkb:Q74U73|uniprotkb:Q7CIA4|uniprotkb:A0A380PD11	psi-mi:ctsre_human(display_long)|uniprotkb:CATSPERE(gene name)|psi-mi:CATSPERE(display_short)|uniprotkb:C1orf101(gene name synonym)	psi-mi:a0a3n4b418_yerpe(display_long)|uniprotkb:YPO2020(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874590|imex:IM-13779-8175	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011542441.1|refseq:XP_011542444.1|refseq:XP_011542451.1|refseq:NP_001124429.1|refseq:NP_001229269.1|refseq:NP_776168.1|refseq:XP_016856435.1|refseq:XP_016856438.1|refseq:XP_016856439.1|ensembl:ENSG00000179397.18(gene)|ensembl:ENST00000366534.9(transcript)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0036128""(CatSper complex)|go:""GO:0048240""(sperm capacitation)|go:""GO:0097228""(sperm principal piece)|interpro:IPR028751|interpro:IPR053814|interpro:IPR053815|interpro:IPR053816|interpro:IPR053817|interpro:IPR053818|panther:PTHR33722(orthology-group)"	refseq:YP_002347006.1|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032698|refseq:WP_002211233.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TJPhD2DB2XT1i8TDW/5tgaryEWk9606	rogid:wzxT1bjS3dgwqWVrMmCge2eTVT0632	intact-crc:9A472C409FB6C0F5|rigid:SDEskRuCbkJfd0SVP/Hf4mb7IBI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P69980	uniprotkb:Q8WWB7	intact:EBI-2845444|uniprotkb:P42714|uniprotkb:Q663J5|uniprotkb:P40297	intact:EBI-2874630|uniprotkb:B4DJN4|uniprotkb:A6NH16|uniprotkb:Q8IV07|uniprotkb:Q6UX96|uniprotkb:Q5SZX4|uniprotkb:Q96F65|ensembl:ENSP00000354553.1|ensembl:ENSP00000497576.1	psi-mi:yscr_yerpe(display_long)|uniprotkb:yscR(gene name)|psi-mi:yscR(display_short)|uniprotkb:YPCD1.44(locus name)|uniprotkb:y5034(locus name)|uniprotkb:y0037(locus name)|uniprotkb:YP_pCD39(locus name)	psi-mi:glmp_human(display_long)|uniprotkb:GLMP(gene name)|psi-mi:GLMP(display_short)|uniprotkb:C1orf85(gene name synonym)|uniprotkb:Lysosomal protein NCU-G1(gene name synonym)|uniprotkb:PSEC0030(orf name)|uniprotkb:UNQ2553/PRO6182(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874627|imex:IM-13779-8179	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395178.1|refseq:NP_857738.1|refseq:NP_857933.1|interpro:IPR005838(Type III secretion system inner membrane P protein)|interpro:IPR005773(Yop virulence translocation protein R)|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|refseq:WP_002212947.1|panther:PTHR30587(orthology-group)"	"refseq:NP_653181.1|refseq:NP_001243538.1|ensembl:ENSG00000198715.13(gene)|ensembl:ENST00000362007.6(transcript)|ensembl:ENST00000647767.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050821""(protein stabilization)|go:""GO:0061462""(protein localization to lysosome)|interpro:IPR029382|panther:PTHR31981(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8WQqv7KuV4BZ+uBr2fevGUQFw8E632	rogid:v5KmNg/5Fq/5vg/vzWtGUMD9q109606	intact-crc:7DED65EC2E4AA50E|rigid:m/BEDODuthOqcdHfowhgESRmPdI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YMD4	uniprotkb:Q6NZ36	intact:EBI-2874620|uniprotkb:Q0WKQ9|uniprotkb:A0A454XSV9|uniprotkb:Q7CLA7|uniprotkb:A0A384KZW0	intact:EBI-2817693|uniprotkb:A8MQT6|uniprotkb:Q6ZT64|uniprotkb:A6PW40|uniprotkb:Q71M24|uniprotkb:A6PW39|uniprotkb:A6PW41|uniprotkb:Q96ND7|uniprotkb:F2Z2L4|ensembl:ENSP00000367808.4|intact:EBI-28984154	psi-mi:a0a5p8ymd4_yerpe(display_long)|uniprotkb:YPO0033(locus name)	psi-mi:fap20_human(display_long)|uniprotkb:FANCA-associated protein of 20 kDa(gene name synonym)|uniprotkb:Fanconi anemia-associated protein of 20 kDa(gene name synonym)|uniprotkb:FP7162(orf name)|uniprotkb:FAAP20(gene name)|psi-mi:FAAP20(display_short)|uniprotkb:C1orf86(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874617|imex:IM-13779-8177	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002209007.1|refseq:YP_002345129.1	"refseq:NP_001269599.1|refseq:NP_001269600.1|refseq:NP_001269601.1|refseq:NP_001269602.1|refseq:NP_872339.2|refseq:NP_001243874.1|refseq:NP_001243875.1|refseq:NP_001243876.1|ensembl:ENSG00000162585.17(gene)|ensembl:ENST00000378546.9(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0016604""(nuclear body)|go:""GO:0019985""(translesion synthesis)|go:""GO:0030054""(cell junction)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0036297""(interstrand cross-link repair)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043240""(Fanconi anaemia nuclear complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0140036""(ubiquitin-modified protein reader activity)|interpro:IPR031490|interpro:IPR031491|interpro:IPR052689|mint:Q6NZ36|rcsb pdb:2MUQ|rcsb pdb:2MUR|rcsb pdb:3WWQ|reactome:R-HSA-6783310|reactome:R-HSA-9833482|dip:DIP-59917N|panther:PTHR37862(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:akfnsd5N8Db6tqaz+fA/jvMuPPo632	rogid:Jn2G9RrMwRMLLW4BQ3mBxTXoLkA9606	intact-crc:19E92ADA5E8B8431|rigid:06YKkBa69Q7h95m/sgFSK8lsQqc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2817677	uniprotkb:A0A2U2H442	-	intact:EBI-2850550|uniprotkb:Q74WH5|uniprotkb:A0A5P8YDV2|uniprotkb:Q0WHG4|uniprotkb:Q7CHB4|uniprotkb:A0A384LD81	psi-mi:ca099_human(display_short)|psi-mi:EBI-2817677(display_long)|uniprotkb:C1orf99(gene name)|psi-mi:C1orf99(display_short)	psi-mi:a0a2u2h442_yerpe(display_long)|uniprotkb:YPO1245(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874603|imex:IM-13779-8178	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q0P611(uniprot-removed-ac)	refseq:WP_002208853.1|refseq:YP_002346274.1	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iXUh3yr0XDfsP+3HP1ja4bO6rEA9606	rogid:BxXs1C2W2KnC7YYSP0bq8vjxXow632	intact-crc:07239B99E28A0C37|rigid:Mv8lWg0t7jPlxFuabSDctTtiWo8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6NZ36	uniprotkb:Q8ZDJ2	intact:EBI-2817693|uniprotkb:A8MQT6|uniprotkb:Q6ZT64|uniprotkb:A6PW40|uniprotkb:Q71M24|uniprotkb:A6PW39|uniprotkb:A6PW41|uniprotkb:Q96ND7|uniprotkb:F2Z2L4|ensembl:ENSP00000367808.4|intact:EBI-28984154	intact:EBI-2844031|uniprotkb:Q0WDV6	psi-mi:fap20_human(display_long)|uniprotkb:FANCA-associated protein of 20 kDa(gene name synonym)|uniprotkb:Fanconi anemia-associated protein of 20 kDa(gene name synonym)|uniprotkb:FP7162(orf name)|uniprotkb:FAAP20(gene name)|psi-mi:FAAP20(display_short)|uniprotkb:C1orf86(gene name synonym)	psi-mi:a2mgh_yerpe(display_long)|uniprotkb:YPO2573(locus name)|uniprotkb:y1143(locus name)|uniprotkb:YP_1141(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874610|imex:IM-13779-8176	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269599.1|refseq:NP_001269600.1|refseq:NP_001269601.1|refseq:NP_001269602.1|refseq:NP_872339.2|refseq:NP_001243874.1|refseq:NP_001243875.1|refseq:NP_001243876.1|ensembl:ENSG00000162585.17(gene)|ensembl:ENST00000378546.9(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0016604""(nuclear body)|go:""GO:0019985""(translesion synthesis)|go:""GO:0030054""(cell junction)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0036297""(interstrand cross-link repair)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043240""(Fanconi anaemia nuclear complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0140036""(ubiquitin-modified protein reader activity)|interpro:IPR031490|interpro:IPR031491|interpro:IPR052689|mint:Q6NZ36|rcsb pdb:2MUQ|rcsb pdb:2MUR|rcsb pdb:3WWQ|reactome:R-HSA-6783310|reactome:R-HSA-9833482|dip:DIP-59917N|panther:PTHR37862(orthology-group)"	"interpro:IPR021868|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|go:""GO:0004866""(endopeptidase inhibitor activity)|interpro:IPR041203|interpro:IPR041246|interpro:IPR041462|refseq:YP_002347532.1|interpro:IPR051802|panther:PTHR40094(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Jn2G9RrMwRMLLW4BQ3mBxTXoLkA9606	rogid:9FN1refl1me6jgo6ehCPO8MzV8Y632	intact-crc:276C23EA9A0D7015|rigid:frSNaOL0C7ydJpzdHdjUaGpscb0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4AYX8	uniprotkb:Q5JTJ3	intact:EBI-2874672|uniprotkb:Q74SP8|uniprotkb:Q7CJP7|uniprotkb:A0A0H2W580	intact:EBI-2874677|uniprotkb:Q8TA88|uniprotkb:Q5JTJ4|uniprotkb:Q5JTJ2|ensembl:ENSP00000355572.1	"psi-mi:a0a3n4ayx8_yerpe(display_long)|uniprotkb:adgA(gene name)|psi-mi:adgA(display_short)|uniprotkb:""NAD(+) synthase [glutamine-hydrolyzing]""(gene name synonym)|uniprotkb:nadE(gene name synonym)|uniprotkb:YPO2912(locus name)"	psi-mi:coa6_human(display_long)|uniprotkb:COA6(gene name)|psi-mi:COA6(display_short)|uniprotkb:C1orf31(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874669|imex:IM-13779-8183	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR022310|interpro:IPR003694(NAD+ synthase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR000132(Nitrilase/cyanide hydratase, conserved site)|refseq:WP_002211555.1|interpro:IPR014445(""Glutamine-dependent NAD(+) synthetase, GAT region"")|interpro:IPR036526|go:""GO:0000257""(nitrilase activity)|go:""GO:0003952""(""NAD+ synthase (glutamine-hydrolyzing) activity"")|go:""GO:0004359""(glutaminase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008795""(NAD+ synthase activity)|go:""GO:0009435""(NAD biosynthetic process)|refseq:YP_002347844.1|panther:PTHR23090(orthology-group)"	"ensembl:ENSG00000168275.16(gene)|ensembl:ENST00000366613.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005507""(copper ion binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005886""(plasma membrane)|go:""GO:0008535""(respiratory chain complex IV assembly)|go:""GO:0042774""(plasma membrane ATP synthesis coupled electron transport)|go:""GO:0042775""(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR036549|interpro:IPR042289|interpro:IPR048280|rcsb pdb:6NL3|rcsb pdb:6PCE|rcsb pdb:6PCF|reactome:R-HSA-1268020|refseq:NP_001013003.1|refseq:NP_001193570.2|refseq:NP_001288662.1|efo:""Orphanet:1561""|panther:PTHR46690(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H0VHcjQGi44DFB0hfO0bAangXvI632	rogid:RhW1GWfW6148hd0Pa3uXIkRYkRY9606	intact-crc:712521AAF9F58FA7|rigid:DSYelhgbT9yhiki4l6mdzHU0Sl4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BUV0	uniprotkb:A0A380PLW1	intact:EBI-745604|uniprotkb:Q49AA4|uniprotkb:Q5TH71|uniprotkb:Q9GZP6|uniprotkb:A8K917|ensembl:ENSP00000243189.7	intact:EBI-2868067|uniprotkb:Q74RT9|uniprotkb:A0A0H2W6X2|uniprotkb:Q7CGE5|uniprotkb:A0A384LC41	psi-mi:rsrp1_human(display_long)|uniprotkb:RSRP1(gene name)|psi-mi:RSRP1(display_short)|uniprotkb:C1orf63(gene name synonym)|uniprotkb:HT033(orf name)|uniprotkb:NPD014(orf name)	psi-mi:a0a380plw1_yerpe(display_long)|uniprotkb:YPO0610(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874651|imex:IM-13779-8180	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_064713.3|refseq:NP_001308701.1|refseq:XP_011540099.1|ensembl:ENSG00000117616.18(gene)|ensembl:ENST00000243189.12(transcript)|go:""GO:0000245""(spliceosomal complex assembly)|go:""GO:0005634""(nucleus)|interpro:IPR029656|mint:Q9BUV0|panther:PTHR47622(orthology-group)"	"interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR048771|interpro:IPR037018|interpro:IPR053831|refseq:WP_002214212.1|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR052047|go:""GO:0005975""(carbohydrate metabolic process)|refseq:YP_002345679.1|panther:PTHR37469(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IugruP8t4mowi3v7H1DCMkmPBhI9606	rogid:zbf0OQe51O4fnN7gTIrEGSY57rA632	intact-crc:8AA7CD390BF9C9E9|rigid:mRWaTsBh1C24s+1AuHFU3+716Gw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H0K6	uniprotkb:Q9Y3Y2	intact:EBI-2852628|uniprotkb:A0A3N4B3P8|uniprotkb:Q0WDD4|uniprotkb:Q7CJB1|uniprotkb:A0A384KN94	intact:EBI-347794|uniprotkb:Q2VPI9|uniprotkb:Q5T7Y8|uniprotkb:Q5T7Z0|uniprotkb:Q6NSM4|uniprotkb:Q6PB28|uniprotkb:Q8WYT9|ensembl:ENSP00000357683.3|uniprotkb:Q9BUC5|uniprotkb:Q9H034|uniprotkb:Q9H2L0|uniprotkb:Q0VAQ8|uniprotkb:D3DV55|uniprotkb:Q5T7Y9	psi-mi:a0a2u2h0k6_yerpe(display_long)|uniprotkb:fabB(gene name)|psi-mi:fabB(display_short)|uniprotkb:fabC(gene name synonym)|uniprotkb:YPO2757(locus name)|uniprotkb:3-oxoacyl-[acyl-carrier-protein] synthase I(gene name synonym)|uniprotkb:Beta-ketoacyl-ACP synthase I(gene name synonym)	psi-mi:chtop_human(display_long)|uniprotkb:HT031(orf name)|uniprotkb:PP7704(orf name)|uniprotkb:FOP(gene name synonym)|uniprotkb:CHTOP(gene name)|psi-mi:CHTOP(display_short)|uniprotkb:C1orf77(gene name synonym)|uniprotkb:Friend of PRMT1 protein(gene name synonym)|uniprotkb:Small arginine- and glycine-rich protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874644|imex:IM-13779-8182	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018201|rcsb pdb:3OYT|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016039(Thiolase-like)|refseq:WP_002209717.1|interpro:IPR020841|go:""GO:0004315""(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006633""(fatty acid biosynthetic process)|interpro:IPR000794(Beta-ketoacyl synthase)|refseq:YP_002347704.1"	"ensembl:ENSG00000160679.14(gene)|ensembl:ENST00000368694.8(transcript)|go:""GO:0000346""(transcription export complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0008327""(methyl-CpG binding)|go:""GO:0016607""(nuclear speck)|go:""GO:0032781""(positive regulation of ATP-dependent activity)|go:""GO:0051096""(positive regulation of helicase activity)|interpro:IPR025715|interpro:IPR052656|mint:Q9Y3Y2|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_001193541.1|refseq:NP_056422.2|refseq:NP_001231593.1|refseq:NP_001304006.1|panther:PTHR48338(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+3E+vKvbzG7y9HxBalF+akckeKw632	rogid:mNq0QTGQnGABQwIL2S90Hbp3Nm89606	intact-crc:026E88355FCE7915|rigid:82bEigS8AA0fYYSDN/XtArPKhSA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CHA0	uniprotkb:Q9BV19	intact:EBI-2861572|uniprotkb:Q74WF5	intact:EBI-2874661|ensembl:ENSP00000361603.4	psi-mi:q7cha0_yerpe(display_long)|uniprotkb:ompC1(gene name synonym)|uniprotkb:YP_0916(locus name)|uniprotkb:y2966(locus name)|uniprotkb:ompC(gene name)|psi-mi:ompC(display_short)	psi-mi:ca050_human(display_long)|uniprotkb:C1orf50(gene name)|psi-mi:C1orf50(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874658|imex:IM-13779-8181	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001897(Porin, bacterial type)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR050298|interpro:IPR033900|interpro:IPR023614|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0046930""(pore complex)"	"ensembl:ENSG00000164008.17(gene)|ensembl:ENST00000372525.7(transcript)|go:""GO:0042802""(identical protein binding)|interpro:IPR019534|mint:Q9BV19|refseq:NP_077002.2|panther:PTHR14553(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lWS3wuw1DucPSpQ9yjzPQnjXceg632	rogid:TZfvza3lr44CQW5Piu+83qv5Igo9606	intact-crc:A80748BEDECC631B|rigid:rsxrLi86ZTo6GP0Bl7cOII5VeJc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q74XD3	uniprotkb:Q9P296	intact:EBI-2855960|uniprotkb:Q8ZIY8|uniprotkb:Q0WJW4|uniprotkb:Q7CKN0	intact:EBI-2874691|uniprotkb:B2RA09|ensembl:ENSP00000471184.1|ensembl:ENSP00000472620.1	psi-mi:cuta_yerpe(display_long)|uniprotkb:cutA(gene name)|psi-mi:cutA(display_short)|uniprotkb:YPO0346(locus name)|uniprotkb:y0604(locus name)|uniprotkb:YP_0500(locus name)	psi-mi:c5ar2_human(display_long)|uniprotkb:C5AR2(gene name)|psi-mi:C5AR2(display_short)|uniprotkb:C5L2(gene name synonym)|uniprotkb:Complement component 5a receptor 2(gene name synonym)|uniprotkb:G-protein coupled receptor 77(gene name synonym)|uniprotkb:GPR77(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874688|imex:IM-13779-8188	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002209122.1|interpro:IPR023700|interpro:IPR004323(Divalent ion tolerance protein, CutA1)|interpro:IPR011322(Nitrogen regulatory PII-like, alpha/beta)|rcsb pdb:3GSD|interpro:IPR015867(Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal)|go:""GO:0005507""(copper ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0010038""(response to metal ion)|refseq:YP_002345424.1|panther:PTHR23419(orthology-group)"	"refseq:XP_011525038.1|refseq:NP_060955.1|refseq:NP_001258678.1|refseq:NP_001258679.1|ensembl:ENSG00000134830.6(gene)|ensembl:ENST00000595464.3(transcript)|ensembl:ENST00000600626.1(transcript)|go:""GO:0002430""(complement receptor mediated signaling pathway)|go:""GO:0004878""(complement component C5a receptor activity)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007200""(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0032677""(regulation of interleukin-8 production)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0045177""(apical part of cell)|go:""GO:0090024""(negative regulation of neutrophil chemotaxis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000826(Formyl/methionyl peptide receptor)|interpro:IPR002234(Anaphylatoxin chemotactic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q9P296|reactome:R-HSA-375276|reactome:R-HSA-977606|panther:PTHR24225(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oZ+dqE3f5QFb+ouShZmMFoGk+4Q632	rogid:EMLWA0JyCErRW3X2T/uQw27gm6E9606	intact-crc:9EE13300F2E0F89A|rigid:uEa7Z2yllFX5EzRLd04zKXvFFUQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A7Y8RCW6	uniprotkb:P09871	intact:EBI-2845056|uniprotkb:Q7CKM5|uniprotkb:A0A5P8YBL8|uniprotkb:Q0WJU7	intact:EBI-2810045|uniprotkb:Q9UCU9|uniprotkb:Q9UCV3|uniprotkb:Q9UCU7|uniprotkb:Q9UCV5|uniprotkb:Q9UCV4|uniprotkb:Q9UCU8|uniprotkb:Q9UCV2|uniprotkb:Q9UCV1|uniprotkb:Q9UCV0|uniprotkb:Q9UM14|uniprotkb:D3DUT4|ensembl:ENSP00000328173.3|ensembl:ENSP00000354057.5|ensembl:ENSP00000385035.1	psi-mi:a0a7y8rcw6_yerpe(display_long)|uniprotkb:YPO0363(locus name)	psi-mi:c1s_human(display_long)|uniprotkb:C1S(gene name)|psi-mi:C1S(display_short)|uniprotkb:C1 esterase(gene name synonym)|uniprotkb:Complement component 1 subcomponent s(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874714|imex:IM-13779-8185	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR024393|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR011066(Mechanosensitive ion channel MscS, C-terminal)|interpro:IPR006685(Mechanosensitive ion channel MscS)|interpro:IPR011014(Mechanosensitive ion channel MscS, transmembrane-2)|interpro:IPR006686(Mechanosensitive ion channel MscS, conserved site)|interpro:IPR025692|go:""GO:0005886""(plasma membrane)|go:""GO:0008381""(mechanosensitive monoatomic ion channel activity)|interpro:IPR049142|interpro:IPR049278|interpro:IPR023408|refseq:YP_002345441.1|interpro:IPR052702"	"ensembl:ENSG00000182326.17(gene)|ensembl:ENST00000328916.7(transcript)|ensembl:ENST00000360817.10(transcript)|ensembl:ENST00000406697.5(transcript)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0072562""(blood microparticle)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR024175|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR043504|mint:P09871|rcsb pdb:1ELV|rcsb pdb:1NZI|rcsb pdb:4J1Y|rcsb pdb:4LMF|rcsb pdb:4LOR|rcsb pdb:4LOS|rcsb pdb:4LOT|rcsb pdb:6F1C|rcsb pdb:6F1H|rcsb pdb:8GMN|rcsb pdb:8TYP|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|refseq:NP_001333779.1|refseq:NP_001725.1|refseq:NP_958850.1|refseq:XP_005253817.1|efo:""Orphanet:169147""|efo:""Orphanet:75392""|panther:PTHR24255(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:z6l0v0GxSQqbhV/esC/hffWqLG8632	rogid:3zz5RwIqLyPO71zdCp5Vx7aVl+Y9606	intact-crc:222B4F2DE1310B1F|rigid:+OFTvCLO6RxUA5WHas5tx69GcYo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P02746	uniprotkb:A0A5P8YJY7	intact:EBI-2813376|uniprotkb:Q96H17|uniprotkb:Q5T959	intact:EBI-2874721|uniprotkb:Q74PP7|uniprotkb:Q7CL80|uniprotkb:Q0WAW0	psi-mi:c1qb_human(display_long)|uniprotkb:C1QB(gene name)|psi-mi:C1QB(display_short)	psi-mi:a0a5p8yjy7_yerpe(display_long)|uniprotkb:treC(gene name synonym)|uniprotkb:olgH(gene name)|psi-mi:olgH(display_short)|uniprotkb:YPO3696(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874726|imex:IM-13779-8186	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005602""(complement component C1 complex)|go:""GO:0006956""(complement activation)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0045087""(innate immune response)|go:""GO:0045202""(synapse)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0062167""(complement component C1q complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0098794""(postsynapse)|go:""GO:0098883""(synapse pruning)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR050392|mint:P02746|rcsb pdb:1PK6|rcsb pdb:2JG8|rcsb pdb:2JG9|rcsb pdb:2WNU|rcsb pdb:2WNV|rcsb pdb:5HKJ|rcsb pdb:5HZF|rcsb pdb:6FCZ|rcsb pdb:6Z6V|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|refseq:NP_000482.3|refseq:XP_011540361.1|efo:""Orphanet:169147""|panther:PTHR15427(orthology-group)"	"interpro:IPR045857|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR012769(Alpha,alpha-phosphotrehalase)|refseq:WP_002210104.1|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|go:""GO:0004556""(alpha-amylase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005993""(trehalose catabolic process)|go:""GO:0008788""(alpha,alpha-phosphotrehalase activity)|go:""GO:0009313""(oligosaccharide catabolic process)|refseq:YP_002348578.1|panther:PTHR10357(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:K8MXRS5Vqyts/FhcmJMJce4t/109606	rogid:xvv4AvrQ7E2VejUGEHJHjPfvAs0632	intact-crc:2A76EB3AA619C4F7|rigid:0agkfROOSwDy2r8QDCevpiC6zeM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09871	uniprotkb:A0A3N4AWJ5	intact:EBI-2810045|uniprotkb:Q9UCU9|uniprotkb:Q9UCV3|uniprotkb:Q9UCU7|uniprotkb:Q9UCV5|uniprotkb:Q9UCV4|uniprotkb:Q9UCU8|uniprotkb:Q9UCV2|uniprotkb:Q9UCV1|uniprotkb:Q9UCV0|uniprotkb:Q9UM14|uniprotkb:D3DUT4|ensembl:ENSP00000328173.3|ensembl:ENSP00000354057.5|ensembl:ENSP00000385035.1	intact:EBI-2847256|uniprotkb:Q74PQ9|uniprotkb:Q0WB76|uniprotkb:Q7CL89|uniprotkb:A0A384LBM9	psi-mi:c1s_human(display_long)|uniprotkb:C1S(gene name)|psi-mi:C1S(display_short)|uniprotkb:C1 esterase(gene name synonym)|uniprotkb:Complement component 1 subcomponent s(gene name synonym)	psi-mi:a0a3n4awj5_yerpe(display_long)|uniprotkb:yrbF(gene name)|psi-mi:yrbF(display_short)|uniprotkb:YPO3575(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874707|imex:IM-13779-8187	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000182326.17(gene)|ensembl:ENST00000328916.7(transcript)|ensembl:ENST00000360817.10(transcript)|ensembl:ENST00000406697.5(transcript)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0072562""(blood microparticle)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR024175|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR043504|mint:P09871|rcsb pdb:1ELV|rcsb pdb:1NZI|rcsb pdb:4J1Y|rcsb pdb:4LMF|rcsb pdb:4LOR|rcsb pdb:4LOS|rcsb pdb:4LOT|rcsb pdb:6F1C|rcsb pdb:6F1H|rcsb pdb:8GMN|rcsb pdb:8TYP|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|refseq:NP_001333779.1|refseq:NP_001725.1|refseq:NP_958850.1|refseq:XP_005253817.1|efo:""Orphanet:169147""|efo:""Orphanet:75392""|panther:PTHR24255(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|refseq:WP_002210121.1|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_002348462.1|panther:PTHR43023(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3zz5RwIqLyPO71zdCp5Vx7aVl+Y9606	rogid:41Lazbw64n8TP2mcGpcO+u5SiIo632	intact-crc:7F2B31FC97F2822C|rigid:TfjYH3C4bB1HpmZFSwHstAQE8GA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CWH7	uniprotkb:P09871	intact:EBI-2872251|uniprotkb:Q74X01	intact:EBI-2810045|uniprotkb:Q9UCU9|uniprotkb:Q9UCV3|uniprotkb:Q9UCU7|uniprotkb:Q9UCV5|uniprotkb:Q9UCV4|uniprotkb:Q9UCU8|uniprotkb:Q9UCV2|uniprotkb:Q9UCV1|uniprotkb:Q9UCV0|uniprotkb:Q9UM14|uniprotkb:D3DUT4|ensembl:ENSP00000328173.3|ensembl:ENSP00000354057.5|ensembl:ENSP00000385035.1	psi-mi:q8cwh7_yerpe(display_long)|uniprotkb:emrR(gene name)|psi-mi:emrR(display_short)|uniprotkb:YP_0666(locus name)|uniprotkb:y0923(locus name)	psi-mi:c1s_human(display_long)|uniprotkb:C1S(gene name)|psi-mi:C1S(display_short)|uniprotkb:C1 esterase(gene name synonym)|uniprotkb:Complement component 1 subcomponent s(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874700|imex:IM-13779-8184	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000835(Bacterial regulatory protein, MarR)|interpro:IPR023187|interpro:IPR036388|interpro:IPR036390|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)"	"ensembl:ENSG00000182326.17(gene)|ensembl:ENST00000328916.7(transcript)|ensembl:ENST00000360817.10(transcript)|ensembl:ENST00000406697.5(transcript)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0072562""(blood microparticle)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR024175|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR043504|mint:P09871|rcsb pdb:1ELV|rcsb pdb:1NZI|rcsb pdb:4J1Y|rcsb pdb:4LMF|rcsb pdb:4LOR|rcsb pdb:4LOS|rcsb pdb:4LOT|rcsb pdb:6F1C|rcsb pdb:6F1H|rcsb pdb:8GMN|rcsb pdb:8TYP|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|refseq:NP_001333779.1|refseq:NP_001725.1|refseq:NP_958850.1|refseq:XP_005253817.1|efo:""Orphanet:169147""|efo:""Orphanet:75392""|panther:PTHR24255(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SSbIqyjoSChm/QALWOJk5vF9uiQ632	rogid:3zz5RwIqLyPO71zdCp5Vx7aVl+Y9606	intact-crc:AE231B29D5366849|rigid:8Mdc7pxuXqCrkznuWnC0HSWrV+Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20290	uniprotkb:A0A3G5L9M4	intact:EBI-1054687|uniprotkb:Q13893|uniprotkb:Q76M56|uniprotkb:A8K510|ensembl:ENSP00000369965.3	intact:EBI-2844699	psi-mi:btf3_human(display_long)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym)	psi-mi:a0a3g5l9m4_yerpe(display_long)|uniprotkb:yceD_2(gene name synonym)|uniprotkb:NCTC5923_03599(orf name)|uniprotkb:y0556(locus name)|uniprotkb:terA(gene name)|psi-mi:terA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874747|imex:IM-13779-8190	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001032726.1|refseq:NP_001198.2|ensembl:ENSG00000145741.17(gene)|ensembl:ENST00000380591.8(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005854""(nascent polypeptide-associated complex)|go:""GO:0015031""(protein transport)|go:""GO:1905551""(negative regulation of protein localization to endoplasmic reticulum)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|mint:P20290|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:7QWQ|rcsb pdb:7QWR|rcsb pdb:9F1B|rcsb pdb:9F1C|rcsb pdb:9F1D|rcsb pdb:9FQ0|panther:PTHR10351(orthology-group)"	"go:""GO:0046690""(response to tellurium ion)|uniprotkb:A0A2U2H1B9(uniprot-removed-ac)|interpro:IPR003325(Bacterial stress protein)|interpro:IPR017115(Tellurite resistance, TerA)|refseq:WP_002209075.1|interpro:IPR051324"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TU7PtK2KVrzmdfaTdWcHloiRZYg9606	rogid:pmp0dKUKap1cp8P701GLyujbyQ8632	intact-crc:7B6CEBFE6557C9A9|rigid:Bww41090Y9z9HWhQYqObuGN8C+k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14981	uniprotkb:Q8CWG4	intact:EBI-1043840|uniprotkb:O43578|uniprotkb:B4E0W6|ensembl:ENSP00000265990.6	intact:EBI-2856530|uniprotkb:Q74QZ9	"psi-mi:btaf1_human(display_long)|uniprotkb:BTAF1(gene name)|psi-mi:BTAF1(display_short)|uniprotkb:TAF172(gene name synonym)|uniprotkb:ATP-dependent helicase BTAF1(gene name synonym)|uniprotkb:TBP-associated factor 172(gene name synonym)|uniprotkb:""TAF(II)170""(gene name synonym)|uniprotkb:B-TFIID transcription factor-associated 170 kDa subunit(gene name synonym)"	psi-mi:q8cwg4_yerpe(display_long)|uniprotkb:glpD(gene name)|psi-mi:glpD(display_short)|uniprotkb:YP_3299(locus name)|uniprotkb:y3891(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874761|imex:IM-13779-8193	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003963.1|ensembl:ENSG00000095564.15(gene)|ensembl:ENST00000265990.12(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017025""(TBP-class protein binding)|go:""GO:0035562""(negative regulation of chromatin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022707|interpro:IPR027417|interpro:IPR038718|interpro:IPR044078|interpro:IPR044972|interpro:IPR049730|mint:O14981|panther:PTHR36498(orthology-group)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR031656|go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0006072""(glycerol-3-phosphate metabolic process)|go:""GO:0009331""(""glycerol-3-phosphate dehydrogenase (FAD) complex"")|interpro:IPR038299|interpro:IPR036188"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TUDUowqheA9/EO9RjuCwgwa6HY49606	rogid:R9I22ZXVmXiKYYz/+NgwNjlHCb0632	intact-crc:C9568DEB12CA24AC|rigid:RauXE/oMBj1oV8nvO9myskPQDfY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96Q07	uniprotkb:A0A0H2W8E2	intact:EBI-2510245|uniprotkb:Q494V9|uniprotkb:Q96M00|uniprotkb:Q494W1|ensembl:ENSP00000418751.1|ensembl:ENSP00000497066.1	intact:EBI-2845898|uniprotkb:Q74Q33|uniprotkb:Q0WJG5|uniprotkb:Q7CG91|uniprotkb:A0A2U2H085|uniprotkb:A0A384KB95	psi-mi:btbd9_human(display_long)|uniprotkb:BTBD9(gene name)|psi-mi:BTBD9(display_short)|uniprotkb:KIAA1880(gene name synonym)	psi-mi:a0a0h2w8e2_yerpe(display_long)|uniprotkb:YPO0500(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874754|imex:IM-13779-8191	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011512581.1|refseq:NP_001092742.1|refseq:NP_001165889.1|refseq:NP_443125.1|refseq:NP_689946.2|ensembl:ENSG00000183826.19(gene)|ensembl:ENST00000481247.6(transcript)|ensembl:ENST00000649492.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0007616""(long-term memory)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0042428""(serotonin metabolic process)|go:""GO:0042748""(circadian sleep/wake cycle, non-REM sleep)|go:""GO:0048512""(circadian behavior)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050951""(sensory perception of temperature stimulus)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR034091|interpro:IPR052407|mint:Q96Q07|panther:PTHR46306(orthology-group)"	interpro:IPR008312(Uncharacterised conserved protein UCP028301)|refseq:WP_002210481.1|refseq:YP_002345573.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cjdtAwudivBKATkCJ5R/vYLhx4g9606	rogid:r1UlnEbb/K20reicDTxy4VHlP90632	intact-crc:A64EC6F741B93A55|rigid:f2js9bi0o4UBY9P1X60u7aReSX4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P02746	uniprotkb:A0A5P8YGC5	intact:EBI-2813376|uniprotkb:Q96H17|uniprotkb:Q5T959	intact:EBI-2849807|uniprotkb:Q74VU0|uniprotkb:Q0WH08|uniprotkb:A0A2U2GUY6|uniprotkb:Q7CHK1|uniprotkb:A0A384LBD8	psi-mi:c1qb_human(display_long)|uniprotkb:C1QB(gene name)|psi-mi:C1QB(display_short)	psi-mi:a0a5p8ygc5_yerpe(display_long)|uniprotkb:YPO1407(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874733|imex:IM-13779-8189	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005602""(complement component C1 complex)|go:""GO:0006956""(complement activation)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0045087""(innate immune response)|go:""GO:0045202""(synapse)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0062167""(complement component C1q complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0098794""(postsynapse)|go:""GO:0098883""(synapse pruning)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR050392|mint:P02746|rcsb pdb:1PK6|rcsb pdb:2JG8|rcsb pdb:2JG9|rcsb pdb:2WNU|rcsb pdb:2WNV|rcsb pdb:5HKJ|rcsb pdb:5HZF|rcsb pdb:6FCZ|rcsb pdb:6Z6V|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|refseq:NP_000482.3|refseq:XP_011540361.1|efo:""Orphanet:169147""|panther:PTHR15427(orthology-group)"	"interpro:IPR005490(ErfK/YbiS/YcfS/YnhG)|interpro:IPR002477(Peptidoglycan binding-like)|refseq:WP_002217987.1|go:""GO:0004180""(carboxypeptidase activity)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016740""(transferase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR038063|interpro:IPR036365|refseq:YP_002346430.1|interpro:IPR052905|interpro:IPR036366|interpro:IPR045380"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:K8MXRS5Vqyts/FhcmJMJce4t/109606	rogid:+H76sYlvscVAOr5fESmEns/NtHE632	intact-crc:1B2A773D215DF436|rigid:5CAMGwirjeivnI7xXttGuWwpiJI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A384KL32	uniprotkb:Q7L1Q6	intact:EBI-2855180|uniprotkb:Q74WI8|uniprotkb:Q7CHC3|uniprotkb:Q0WHF1	intact:EBI-1046727|ensembl:ENSP00000386474.1|intact:EBI-1051097|uniprotkb:Q14281|uniprotkb:Q15394|uniprotkb:Q9BUY0|uniprotkb:B4DLZ8|uniprotkb:B4DWF7|intact:EBI-21351780	psi-mi:a0a384kl32_yerpe(display_long)|uniprotkb:YPO1258(locus name)	psi-mi:5mp2_human(display_long)|uniprotkb:BZW1(gene name)|psi-mi:BZW1(display_short)|uniprotkb:BZAP45(gene name synonym)|uniprotkb:KIAA0005(gene name synonym)|uniprotkb:Protein Orf(gene name synonym)|uniprotkb:5MP2(gene name synonym)|uniprotkb:Basic leucine zipper and W2 domain-containing protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874740|imex:IM-13779-8192	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052947|interpro:IPR016583(Uncharacterised conserved protein UCP011452, HNH endonuclease domain, YhhZ)|interpro:IPR003615(HNH nuclease)|refseq:WP_002208839.1|interpro:IPR044925|panther:PTHR34319(orthology-group)	"ensembl:ENSG00000082153.18(gene)|ensembl:ENST00000409600.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016020""(membrane)|go:""GO:0045296""(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|interpro:IPR051245|mint:Q7L1Q6|refseq:NP_001193996.1|refseq:NP_055485.2|refseq:NP_001193997.1|refseq:NP_001193998.1|refseq:NP_001308617.1|refseq:NP_001308619.1|refseq:NP_001308620.1|refseq:NP_001308622.1|refseq:NP_001308623.1|panther:PTHR14208(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:k8VGxxWPx+NdmGLFn262erw8Wf8632	rogid:4dzFp6AN4tymPA5rHNYlHCCmSaY9606	intact-crc:704EAACCAF671076|rigid:PV1B7pJDktNOXxSJUwQOSavs/cg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARN5	uniprotkb:O14981	intact:EBI-2839967|uniprotkb:Q7CKL5|uniprotkb:Q74YZ9|uniprotkb:Q7ARK5|uniprotkb:Q7BTY3|uniprotkb:Q7BT06|uniprotkb:A0A1U8QKK8|uniprotkb:A0A3G5LBZ8|uniprotkb:A0A3G5L3F7	intact:EBI-1043840|uniprotkb:O43578|uniprotkb:B4E0W6|ensembl:ENSP00000265990.6	psi-mi:q7arn5_yerpe(display_long)|uniprotkb:ypmt1(gene name synonym)|uniprotkb:YPCD1.01(locus name)|uniprotkb:YPMT1.01(locus name)|uniprotkb:YPMT1.58c(locus name)|uniprotkb:YPPCP1.01(locus name)|uniprotkb:y1093(gene name)|psi-mi:y1093(display_short)|uniprotkb:YPO0031(locus name)|uniprotkb:YPO0171(locus name)|uniprotkb:YPO0249(locus name)|uniprotkb:YPO0386(locus name)|uniprotkb:YPO0528(locus name)|uniprotkb:YPO0567(locus name)|uniprotkb:YPO0637(locus name)|uniprotkb:YPO0780(locus name)|uniprotkb:YPO0826(locus name)|uniprotkb:YPO0924(locus name)|uniprotkb:YPO1013(locus name)|uniprotkb:YPO1086(locus name)|uniprotkb:YPO1132(locus name)|uniprotkb:YPO1338(locus name)|uniprotkb:YPO1427(locus name)|uniprotkb:YPO1520(locus name)|uniprotkb:YPO1623(locus name)|uniprotkb:YPO1692(locus name)|uniprotkb:YPO1729(locus name)|uniprotkb:YPO1750(locus name)|uniprotkb:YPO1900(locus name)|uniprotkb:YPO2026(locus name)|uniprotkb:YPO2085(locus name)|uniprotkb:YPO2178(locus name)|uniprotkb:YPO2365(locus name)|uniprotkb:YPO2396(locus name)|uniprotkb:YPO2516(locus name)|uniprotkb:YPO2643(locus name)|uniprotkb:YPO2721(locus name)|uniprotkb:YPO2808(locus name)|uniprotkb:YPO2932(locus name)|uniprotkb:YPO3209(locus name)|uniprotkb:YPO3251(locus name)|uniprotkb:YPO3282(locus name)|uniprotkb:YPO3434(locus name)|uniprotkb:YPO3542(locus name)|uniprotkb:YPO3591(locus name)|uniprotkb:YPO3701(locus name)|uniprotkb:YPO3756(locus name)|uniprotkb:YPO3774(locus name)|uniprotkb:YPO4010(locus name)	"psi-mi:btaf1_human(display_long)|uniprotkb:BTAF1(gene name)|psi-mi:BTAF1(display_short)|uniprotkb:TAF172(gene name synonym)|uniprotkb:ATP-dependent helicase BTAF1(gene name synonym)|uniprotkb:TBP-associated factor 172(gene name synonym)|uniprotkb:""TAF(II)170""(gene name synonym)|uniprotkb:B-TFIID transcription factor-associated 170 kDa subunit(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874768|imex:IM-13779-8196	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002348636.1|refseq:YP_002348652.1|refseq:YP_002348877.1|interpro:IPR017894|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:NP_395138.1|refseq:NP_395227.1|refseq:NP_395336.1|refseq:NP_395402.1|refseq:NP_857638.1|refseq:NP_857716.1|refseq:NP_857780.1|refseq:YP_094025.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR036397|refseq:WP_000255944.1|refseq:YP_006960969.1|go:""GO:0000150""(DNA strand exchange activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0015074""(DNA integration)|go:""GO:0032196""(transposition)|interpro:IPR006120(Resolvase, helix-turn-helix region)|refseq:YP_002345127.1|refseq:YP_002345256.1|refseq:YP_002345330.1|refseq:YP_002345463.1|refseq:YP_002345601.1|refseq:YP_002345638.1|refseq:YP_002345704.1|refseq:YP_002345836.1|refseq:YP_002345880.1|refseq:YP_002345972.1|refseq:YP_002346056.1|refseq:YP_002346129.1|refseq:YP_002346174.1|refseq:YP_002346362.1|refseq:YP_002346450.1|refseq:YP_002346536.1|refseq:YP_002346634.1|refseq:YP_002346730.1|refseq:YP_002346750.1|refseq:YP_002346890.1|refseq:YP_002347010.1|refseq:YP_002347066.1|refseq:YP_002347152.1|refseq:YP_002347332.1|refseq:YP_002347362.1|refseq:YP_002347480.1|refseq:YP_002347596.1|refseq:YP_002347668.1|refseq:YP_002347749.1|refseq:YP_002347862.1|refseq:YP_002348112.1|refseq:YP_002348152.1|refseq:YP_002348181.1|refseq:YP_002348326.1|refseq:YP_002348430.1|refseq:YP_002348476.1|refseq:YP_002346695.1|refseq:YP_002348583.1|panther:PTHR35004(orthology-group)"	"refseq:NP_003963.1|ensembl:ENSG00000095564.15(gene)|ensembl:ENST00000265990.12(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017025""(TBP-class protein binding)|go:""GO:0035562""(negative regulation of chromatin binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022707|interpro:IPR027417|interpro:IPR038718|interpro:IPR044078|interpro:IPR044972|interpro:IPR049730|mint:O14981|panther:PTHR36498(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gYoFpz6mpcJ4NYVEafsAkK14EIE632	rogid:TUDUowqheA9/EO9RjuCwgwa6HY49606	intact-crc:863636F0CD9461FE|rigid:9JjXlrOOYDVSxbhtrxn2css/gHg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YKP4	uniprotkb:Q9NSI6	intact:EBI-2853948|uniprotkb:Q74RP4|uniprotkb:Q7CGH3|uniprotkb:Q0WJ06	intact:EBI-1996384|uniprotkb:C9JK25|uniprotkb:O43721|uniprotkb:Q5R2V0|uniprotkb:Q5R2V1|uniprotkb:Q8TCV3|uniprotkb:Q96QG9|uniprotkb:Q96QH0|uniprotkb:Q9NUK1|ensembl:ENSP00000330753.2|uniprotkb:Q6P2D1	psi-mi:a0a5p8ykp4_yerpe(display_long)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:YPO0664(locus name)	psi-mi:brwd1_human(display_long)|uniprotkb:BRWD1(gene name)|psi-mi:BRWD1(display_short)|uniprotkb:C21orf107(gene name synonym)|uniprotkb:WDR9(gene name synonym)|uniprotkb:WD repeat-containing protein 9(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874782|imex:IM-13779-8195	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020084|interpro:IPR004385(Nucleoside diphosphate pyrophosphatase)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:WP_002212184.1|go:""GO:0005829""(cytosol)|go:""GO:0006753""(nucleoside phosphate metabolic process)|go:""GO:0019144""(ADP-sugar diphosphatase activity)|go:""GO:0019693""(ribose phosphate metabolic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_002345732.1|panther:PTHR11839(orthology-group)"	"refseq:NP_061836.2|refseq:NP_387505.1|ensembl:ENSG00000185658.14(gene)|ensembl:ENST00000333229.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005930""(axoneme)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0031514""(motile cilium)|go:""GO:0060170""(ciliary membrane)|interpro:IPR001487(Bromodomain)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018359|interpro:IPR019775|interpro:IPR036322|interpro:IPR036427|interpro:IPR052060|rcsb pdb:3Q2E|reactome:R-HSA-1266695|reactome:R-HSA-3247509|refseq:NP_001007247.1|panther:PTHR16266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ji/dszpJhw/6y6lx3coWs2NZfpY632	rogid:SOVOGOtyOP21QluLJwTOi7Q/oME9606	intact-crc:2CCF2305F69DBD32|rigid:iRa3HXehDw862OCaGsub79vdKtg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WGQ5	uniprotkb:Q9NW68	intact:EBI-2853517|uniprotkb:Q74VA6|uniprotkb:Q7CHR0	intact:EBI-721848|uniprotkb:B4DMS7|uniprotkb:B4DTP7|uniprotkb:B4E2X8|uniprotkb:Q49AT8|uniprotkb:Q68DY6|uniprotkb:Q6IAA3|uniprotkb:Q6MZK1|uniprotkb:Q6UXS1|uniprotkb:Q9HAL9|uniprotkb:B4DTI7|ensembl:ENSP00000412173.2	psi-mi:q0wgq5_yerpe(display_long)|uniprotkb:YPO1517(locus name)	psi-mi:bsdc1_human(display_long)|uniprotkb:BSDC1(gene name)|psi-mi:BSDC1(display_short)|uniprotkb:UNQ2494/PRO5781(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874775|imex:IM-13779-8194	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050555|interpro:IPR025997|interpro:IPR028082|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002346533.1|panther:PTHR30036(orthology-group)"	"refseq:NP_001137360.1|refseq:NP_001137361.1|refseq:NP_001137362.1|refseq:NP_060515.3|refseq:NP_001287887.1|ensembl:ENSG00000160058.19(gene)|ensembl:ENST00000455895.7(transcript)|go:""GO:0005737""(cytoplasm)|interpro:IPR005607(BSD)|interpro:IPR035925|interpro:IPR051494|mint:Q9NW68|panther:PTHR16019(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qnuiW6B7FZ3gckfa7i2/HzKZAI8632	rogid:xURI5Azk5thRty0BOh6UyxlbB4Y9606	intact-crc:B24A68C30D3A4DD6|rigid:1qQ1be85tovbZlQI+1btFomT5WU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95415	uniprotkb:A0A380PDF6	intact:EBI-2874789|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|ensembl:ENSP00000297290.3|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918	intact:EBI-2856702|uniprotkb:Q74UZ3|uniprotkb:Q7CI04|uniprotkb:A0A0H2W3V4	psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym)|uniprotkb:Brain protein I3(gene name synonym)	psi-mi:a0a380pdf6_yerpe(display_long)|uniprotkb:yecS(gene name)|psi-mi:yecS(display_short)|uniprotkb:YPO1847(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874795|imex:IM-13779-8197	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056194.1|ensembl:ENSG00000164713.10(gene)|ensembl:ENST00000297290.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|refseq:NP_001152963.1|panther:PTHR13551(orthology-group)"	"interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_002211158.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015184""(L-cystine transmembrane transporter activity)|go:""GO:0015811""(L-cystine transport)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|interpro:IPR035906|interpro:IPR043429|refseq:YP_002346841.1|panther:PTHR30614(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606	rogid:pJ27jWvWt/SRd2N+cRvIV71qr60632	intact-crc:3173D2C2D414A4F4|rigid:l9lzrbqKWidD82We8g7jAuBGeTk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60238	uniprotkb:A0A380PE22	intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|ensembl:ENSP00000370003.2|intact:EBI-28977676	intact:EBI-2856011|uniprotkb:A0A0H2W318|uniprotkb:Q74VW4|uniprotkb:Q7CJX4|uniprotkb:A0A384LD58	psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym)	psi-mi:a0a380pe22_yerpe(display_long)|uniprotkb:YPO2801(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874840|imex:IM-13779-8199	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004322.1|dip:DIP-35187N|panther:PTHR15186(orthology-group)|ensembl:ENSG00000104765.16(gene)|ensembl:ENST00000380629.7(transcript)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0010917""(negative regulation of mitochondrial membrane potential)|go:""GO:0016020""(membrane)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016607""(nuclear speck)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043067""(regulation of programmed cell death)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0051607""(defense response to virus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0097345""(mitochondrial outer membrane permeabilization)|go:""GO:1901524""(regulation of mitophagy)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204|refseq:NP_001317420.1"	interpro:IPR018677|refseq:WP_002209756.1|interpro:IPR025513|refseq:YP_002347742.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/13	rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606	rogid:dGYO2y8tXuDYlpLIte+D054U4jc632	intact-crc:4EA67B730BBE1D80|rigid:0RpSN8+B3WcsWr5a+zgWo8Wg+0U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CIP6	uniprotkb:O60238	intact:EBI-2852197|uniprotkb:Q74TN3	intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|ensembl:ENSP00000370003.2|intact:EBI-28977676	psi-mi:q7cip6_yerpe(display_long)|uniprotkb:qacE(gene name)|psi-mi:qacE(display_short)|uniprotkb:YPO2333(locus name)	psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874847|imex:IM-13779-8200	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000390(Small multidrug resistance protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0015199""(amino-acid betaine transmembrane transporter activity)|go:""GO:0015220""(choline transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015871""(choline transport)|go:""GO:0031460""(glycine betaine transport)|go:""GO:0055085""(transmembrane transport)|refseq:YP_002347300.1|interpro:IPR045324|panther:PTHR30561(orthology-group)"	"refseq:NP_004322.1|dip:DIP-35187N|panther:PTHR15186(orthology-group)|ensembl:ENSG00000104765.16(gene)|ensembl:ENST00000380629.7(transcript)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0010917""(negative regulation of mitochondrial membrane potential)|go:""GO:0016020""(membrane)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016607""(nuclear speck)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043067""(regulation of programmed cell death)|go:""GO:0043069""(negative regulation of programmed cell death)|go:""GO:0051607""(defense response to virus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0097345""(mitochondrial outer membrane permeabilization)|go:""GO:1901524""(regulation of mitophagy)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204|refseq:NP_001317420.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/13	rogid:6Ga2PoftjeVUAYBkCvuFol1JigI632	rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606	intact-crc:6AB8E6DF2085885A|rigid:nHQcGdCfFJJV3rWYs/VsgCm/xe0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12982	uniprotkb:Q8ZAE1	intact:EBI-752094|uniprotkb:B4DS94|ensembl:ENSP00000412767.3|ensembl:ENSP00000475320.1	intact:EBI-2840869|uniprotkb:Q0WAE4	psi-mi:bnip2_human(display_long)|uniprotkb:BNIP2(gene name)|psi-mi:BNIP2(display_short)|uniprotkb:NIP2(gene name synonym)	"psi-mi:weca_yerpe(display_long)|uniprotkb:wecA(gene name)|psi-mi:wecA(display_short)|uniprotkb:rfe(gene name synonym)|uniprotkb:""UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase""(gene name synonym)|uniprotkb:Undecaprenyl-phosphate GlcNAc-1-phosphate transferase(gene name synonym)|uniprotkb:YPO3866(locus name)|uniprotkb:y0362(locus name)|uniprotkb:YP_3179(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874833|imex:IM-13779-8201	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004321.2|refseq:NP_001307604.1|ensembl:ENSG00000140299.14(gene)|ensembl:ENST00000415213.7(transcript)|ensembl:ENST00000607373.6(transcript)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0090649""(response to oxygen-glucose deprivation)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR022181|interpro:IPR036865|mint:Q12982|reactome:R-HSA-525793|panther:PTHR12112(orthology-group)"	"interpro:IPR012750(Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase)|interpro:IPR000715(Glycosyl transferase, family 4)|refseq:WP_002211988.1|go:""GO:0000287""(magnesium ion binding)|refseq:YP_002348744.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009103""(lipopolysaccharide biosynthetic process)|go:""GO:0009243""(O antigen biosynthetic process)|go:""GO:0009246""(enterobacterial common antigen biosynthetic process)|go:""GO:0009276""(Gram-negative-bacterium-type cell wall)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0016780""(phosphotransferase activity, for other substituted phosphate groups)|go:""GO:0030145""(manganese ion binding)|go:""GO:0036380""(UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity)|go:""GO:0044038""(cell wall macromolecule biosynthetic process)|go:""GO:0071555""(cell wall organization)|panther:PTHR22926(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:A/xI0cdQ50bAIX/e5AQAyWeUqjs9606	rogid:Pm2Aw3qzZXUu5ytBSzJ9pD7y7uE632	intact-crc:203267751418C194|rigid:qPsbz7/tlkuzMPTttZ+adJFDbqw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BWV1	uniprotkb:A0A5P8YKF6	intact:EBI-718555|uniprotkb:A6NJ30|uniprotkb:Q6UXJ5|uniprotkb:Q8N2P7|uniprotkb:Q8NF26|uniprotkb:B2RMS8|uniprotkb:D3DN70|ensembl:ENSP00000347546.3|ensembl:ENSP00000418663.1	intact:EBI-2874821|uniprotkb:Q74QM9|uniprotkb:A0A0H2W8R3|uniprotkb:A0A2U2GVC1|uniprotkb:Q7CGL9|uniprotkb:A0A384K8P0	psi-mi:boc_human(display_long)|uniprotkb:BOC(gene name)|psi-mi:BOC(display_short)|uniprotkb:UNQ604/PRO1190(orf name)	psi-mi:a0a5p8ykf6_yerpe(display_long)|uniprotkb:gntP(gene name)|psi-mi:gntP(display_short)|uniprotkb:YPO0767(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874826|imex:IM-13779-8198	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_150279.1|refseq:XP_016862940.1|refseq:XP_011511607.1|ensembl:ENSG00000144857.15(gene)|ensembl:ENST00000355385.7(transcript)|ensembl:ENST00000495514.5(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0007399""(nervous system development)|go:""GO:0007411""(axon guidance)|go:""GO:0030424""(axon)|go:""GO:0044295""(axonal growth cone)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3N1G|rcsb pdb:3N1M|rcsb pdb:3N1P|reactome:R-HSA-525793|reactome:R-HSA-5632681|reactome:R-HSA-5635838|refseq:XP_005247948.1|refseq:XP_005247949.1|refseq:NP_001288790.1|panther:PTHR44170(orthology-group)"	"interpro:IPR003474(Gluconate transporter)|refseq:WP_002223676.1|go:""GO:0015128""(gluconate transmembrane transporter activity)|go:""GO:0016020""(membrane)|refseq:YP_002345823.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SQPC0pqcAHVfuJCxq84BSi9k0IA9606	rogid:T4bDyjYOmzjXNuXMDX73PjaZnKo632	intact-crc:109F01DAF6B282DB|rigid:8Dh2MvYUo43ikPGOinU7uwEXzJY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YKP4	uniprotkb:P25440	intact:EBI-2853948|uniprotkb:Q74RP4|uniprotkb:Q7CGH3|uniprotkb:Q0WJ06	intact:EBI-2874802|uniprotkb:Q5STC9|uniprotkb:Q6P3U2|uniprotkb:O00699|uniprotkb:B1AZT1|uniprotkb:B0S7P0|uniprotkb:Q969U4|uniprotkb:Q15310|uniprotkb:O00700|uniprotkb:A2AAU0|uniprotkb:Q63HQ9|uniprotkb:Q658Y7|ensembl:ENSP00000363958.4|ensembl:ENSP00000363964.4|ensembl:ENSP00000372588.2|ensembl:ENSP00000382444.1|ensembl:ENSP00000382445.3|ensembl:ENSP00000391246.2|ensembl:ENSP00000399009.1|ensembl:ENSP00000401791.2|ensembl:ENSP00000409145.3|ensembl:ENSP00000449380.2|ensembl:ENSP00000449609.1|ensembl:ENSP00000502900.1	psi-mi:a0a5p8ykp4_yerpe(display_long)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:YPO0664(locus name)	psi-mi:brd2_human(display_long)|uniprotkb:BRD2(gene name)|psi-mi:BRD2(display_short)|uniprotkb:KIAA9001(gene name synonym)|uniprotkb:RING3(gene name synonym)|uniprotkb:O27.1.1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874814|imex:IM-13779-8202	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020084|interpro:IPR004385(Nucleoside diphosphate pyrophosphatase)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:WP_002212184.1|go:""GO:0005829""(cytosol)|go:""GO:0006753""(nucleoside phosphate metabolic process)|go:""GO:0019144""(ADP-sugar diphosphatase activity)|go:""GO:0019693""(ribose phosphate metabolic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_002345732.1|panther:PTHR11839(orthology-group)"	"ensembl:ENSG00000204256.15(gene)|ensembl:ENSG00000215077.10(gene)|ensembl:ENSG00000234507.9(gene)|ensembl:ENSG00000234704.9(gene)|ensembl:ENSG00000235307.12(gene)|ensembl:ENST00000374825.9(transcript)|ensembl:ENST00000374831.8(transcript)|ensembl:ENST00000383108.6(transcript)|ensembl:ENST00000399528.5(transcript)|ensembl:ENST00000399529.7(transcript)|ensembl:ENST00000414731.6(transcript)|ensembl:ENST00000438194.6(transcript)|ensembl:ENST00000449085.4(transcript)|ensembl:ENST00000449118.5(transcript)|ensembl:ENST00000549126.4(transcript)|ensembl:ENST00000552587.4(transcript)|ensembl:ENST00000678250.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001843""(neural tube closure)|go:""GO:0003682""(chromatin binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016607""(nuclear speck)|go:""GO:0042393""(histone binding)|go:""GO:0070577""(lysine-acetylated histone binding)|go:""GO:0071168""(protein localization to chromatin)|go:""GO:0140033""(acetylation-dependent protein binding)|go:""GO:0140588""(chromatin looping)|go:""GO:2000330""(positive regulation of T-helper 17 cell lineage commitment)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|interpro:IPR050935|mint:P25440|rcsb pdb:1X0J|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2DVS|rcsb pdb:2DVV|rcsb pdb:2E3K|rcsb pdb:2G4A|rcsb pdb:2YDW|rcsb pdb:2YEK|rcsb pdb:3AQA|rcsb pdb:3ONI|rcsb pdb:4A9E|rcsb pdb:4A9F|rcsb pdb:4A9H|rcsb pdb:4A9I|rcsb pdb:4A9J|rcsb pdb:4A9M|rcsb pdb:4A9N|rcsb pdb:4A9O|rcsb pdb:4AKN|rcsb pdb:4ALG|rcsb pdb:4ALH|rcsb pdb:4J1P|rcsb pdb:4MR5|rcsb pdb:4MR6|rcsb pdb:4QEU|rcsb pdb:4QEV|rcsb pdb:4QEW|rcsb pdb:4UYF|rcsb pdb:4UYG|rcsb pdb:4UYH|rcsb pdb:5BT5|rcsb pdb:5DFB|rcsb pdb:5DFC|rcsb pdb:5DFD|rcsb pdb:5DW1|rcsb pdb:5EK9|rcsb pdb:5HEL|rcsb pdb:5HEM|rcsb pdb:5HEN|rcsb pdb:5HFQ|rcsb pdb:5IBN|rcsb pdb:5IG6|rcsb pdb:5N2L|rcsb pdb:5O38|rcsb pdb:5O39|rcsb pdb:5O3A|rcsb pdb:5O3B|rcsb pdb:5O3C|rcsb pdb:5O3D|rcsb pdb:5O3E|rcsb pdb:5O3F|rcsb pdb:5O3G|rcsb pdb:5O3H|rcsb pdb:5O3I|rcsb pdb:5S9O|rcsb pdb:5U5S|rcsb pdb:5U6V|rcsb pdb:5UEW|rcsb pdb:5XHE|rcsb pdb:5XHK|rcsb pdb:6CUI|rcsb pdb:6DB0|rcsb pdb:6DBC|rcsb pdb:6DDI|rcsb pdb:6DDJ|rcsb pdb:6E6J|rcsb pdb:6FFE|rcsb pdb:6FFF|rcsb pdb:6FFG|rcsb pdb:6I80|rcsb pdb:6I81|rcsb pdb:6JKE|rcsb pdb:6K04|rcsb pdb:6K05|rcsb pdb:6MO7|rcsb pdb:6MO8|rcsb pdb:6MO9|rcsb pdb:6MOA|rcsb pdb:6ONY|rcsb pdb:6SWO|rcsb pdb:6SWP|rcsb pdb:6TQ1|rcsb pdb:6TQ2|rcsb pdb:6U61|rcsb pdb:6U71|rcsb pdb:6U8H|rcsb pdb:6ULQ|rcsb pdb:6ULT|rcsb pdb:6VIY|rcsb pdb:6WWB|rcsb pdb:6YTM|rcsb pdb:6Z7F|rcsb pdb:6Z8P|rcsb pdb:6ZB0|rcsb pdb:6ZB1|rcsb pdb:6ZB2|rcsb pdb:7DPN|rcsb pdb:7DPO|rcsb pdb:7ENV|rcsb pdb:7ENZ|rcsb pdb:7EO5|rcsb pdb:7JX7|rcsb pdb:7L6D|rcsb pdb:7L9G|rcsb pdb:7L9J|rcsb pdb:7L9K|rcsb pdb:7LAK|rcsb pdb:7NPY|rcsb pdb:7NPZ|rcsb pdb:7NQ0|rcsb pdb:7NQ1|rcsb pdb:7NQ2|rcsb pdb:7NQ3|rcsb pdb:7NQ5|rcsb pdb:7NQ7|rcsb pdb:7NQ8|rcsb pdb:7NQ9|rcsb pdb:7NQI|rcsb pdb:7NQJ|rcsb pdb:7OE4|rcsb pdb:7OE5|rcsb pdb:7OE6|rcsb pdb:7OE8|rcsb pdb:7OE9|rcsb pdb:7OEP|rcsb pdb:7OER|rcsb pdb:7OES|rcsb pdb:7OET|rcsb pdb:7OGY|rcsb pdb:7Q5O|rcsb pdb:7USG|rcsb pdb:7USH|rcsb pdb:7USI|rcsb pdb:7UU0|rcsb pdb:7VRH|rcsb pdb:7VRI|rcsb pdb:7VRK|rcsb pdb:7VRM|rcsb pdb:7VRO|rcsb pdb:7VRQ|rcsb pdb:7VRZ|rcsb pdb:7VS0|rcsb pdb:7VS1|rcsb pdb:7VSF|rcsb pdb:7WLN|rcsb pdb:7WMQ|rcsb pdb:7WMU|rcsb pdb:7WN5|rcsb pdb:7WNA|rcsb pdb:7WNI|rcsb pdb:8B5G|rcsb pdb:8B5H|rcsb pdb:8B5I|rcsb pdb:8B5J|rcsb pdb:8CV7|rcsb pdb:8DNQ|rcsb pdb:8PX2|rcsb pdb:8PX8|rcsb pdb:8SB6|rcsb pdb:8WYG|rcsb pdb:9FBX|reactome:R-HSA-8951936|dip:DIP-60835N|refseq:NP_001106653.1|refseq:NP_001186384.1|refseq:NP_001186385.1|refseq:NP_001278915.1|refseq:NP_005095.1|panther:PTHR45926(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:ji/dszpJhw/6y6lx3coWs2NZfpY632	rogid:Q3ELpiTZgboufxPDV/bypJZC2oY9606	intact-crc:479BAF68F189FF61|rigid:Rc7vmV1iSnxYNv97em82ofgk638	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P51451	uniprotkb:Q8ZGK8	intact:EBI-2105445|uniprotkb:Q96IN1|uniprotkb:Q16291|ensembl:ENSP00000259089.4|ensembl:ENSP00000494522.3	intact:EBI-2840206|uniprotkb:Q0WHC9	psi-mi:blk_human(display_long)|uniprotkb:BLK(gene name)|psi-mi:BLK(display_short)|uniprotkb:B lymphocyte kinase(gene name synonym)|uniprotkb:p55-Blk(gene name synonym)	psi-mi:uxua_yerpe(display_long)|uniprotkb:uxuA(gene name)|psi-mi:uxuA(display_short)|uniprotkb:D-mannonate hydro-lyase(gene name synonym)|uniprotkb:YPO1283(locus name)|uniprotkb:YP_1308(locus name)|uniprotkb:y2902(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874861|imex:IM-13779-8205	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24418(orthology-group)|efo:""Orphanet:552""|efo:""Orphanet:536""|ensembl:ENSG00000136573.16(gene)|ensembl:ENSG00000285369.3(gene)|ensembl:ENST00000259089.9(transcript)|ensembl:ENST00000646615.3(transcript)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0030154""(cell differentiation)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0045087""(innate immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0140801""(histone H2AXY142 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035853|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P51451|reactome:R-HSA-8939245|reactome:R-HSA-983695|refseq:NP_001706.2"	"interpro:IPR004628(Mannonate dehydratase)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008927""(mannonate dehydratase activity)|go:""GO:0030145""(manganese ion binding)|go:""GO:0042840""(D-glucuronate catabolic process)|refseq:WP_002208813.1|refseq:YP_002346309.1|interpro:IPR036237|panther:PTHR30387(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:z6p1emCKpfhFkpk1GysjT8WEj5g9606	rogid:JhdXu0NB4lbIj/rl4GvHVR+RwwE632	intact-crc:698AC0EEED2B06F4|rigid:CNxrnYNueujeBH7LTWN8yenGV5E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NR09	uniprotkb:Q7ARD3	intact:EBI-1765160|uniprotkb:Q9ULD1|ensembl:ENSP00000393596.2	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:birc6_human(display_long)|uniprotkb:Baculoviral IAP repeat-containing protein 6(gene name synonym)|uniprotkb:BIRC6(gene name)|psi-mi:BIRC6(display_short)|uniprotkb:KIAA1289(gene name synonym)|uniprotkb:Ubiquitin-conjugating BIR domain enzyme apollon(gene name synonym)|uniprotkb:BIR repeat-containing ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874868|imex:IM-13779-8206	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057336.3|ensembl:ENSG00000115760.16(gene)|ensembl:ENST00000421745.7(transcript)|go:""GO:0000922""(spindle pole)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005768""(endosome)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030496""(midbody)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051301""(cell division)|go:""GO:0060711""(labyrinthine layer development)|go:""GO:0061631""(ubiquitin conjugating enzyme activity)|go:""GO:0090543""(Flemming body)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022103|mint:Q9NR09|rcsb pdb:3CEG|rcsb pdb:8ATM|rcsb pdb:8ATO|rcsb pdb:8ATU|rcsb pdb:8ATX|rcsb pdb:8AUK|rcsb pdb:8AUW|rcsb pdb:8E2D|rcsb pdb:8E2E|rcsb pdb:8E2F|rcsb pdb:8E2G|rcsb pdb:8E2H|rcsb pdb:8E2I|rcsb pdb:8E2K|reactome:R-HSA-9700645|reactome:R-HSA-9725370|panther:PTHR46116(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VCOEh/W7S7TLU/gNXfg9SkQMhoc9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:A99281D9E9D70AD2|rigid:avqkCqp6yJksnrxclx1Uk+UpDlQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30043	uniprotkb:P68590	intact:EBI-2837485|uniprotkb:P53005|uniprotkb:P32078|uniprotkb:Q32LZ2|uniprotkb:B2R5C6|uniprotkb:A6NKD8|ensembl:ENSP00000263368.3	intact:EBI-2845098|uniprotkb:Q00929	psi-mi:blvrb_human(display_long)|uniprotkb:BLVRB(gene name)|psi-mi:BLVRB(display_short)|uniprotkb:FLR(gene name synonym)|uniprotkb:Biliverdin reductase B(gene name synonym)|uniprotkb:Biliverdin-IX beta-reductase(gene name synonym)|uniprotkb:Green heme-binding protein(gene name synonym)|uniprotkb:NADPH-dependent diaphorase(gene name synonym)|uniprotkb:NADPH-flavin reductase(gene name synonym)|uniprotkb:S-nitroso-CoA-assisted nitrosyltransferase(gene name synonym)|uniprotkb:SCAN(gene name synonym)	psi-mi:yopr_yerpe(display_long)|uniprotkb:yscH(gene name)|psi-mi:yscH(display_short)|uniprotkb:lcrP(gene name synonym)|uniprotkb:Yersinia outer protein R(gene name synonym)|uniprotkb:Yersinia secretion protein H(gene name synonym)|uniprotkb:yopR(gene name synonym)|uniprotkb:YPCD1.57(locus name)|uniprotkb:YP_pCD26(locus name)|uniprotkb:y0024(locus name)|uniprotkb:y5021(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874854|imex:IM-13779-8203	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090013.11(gene)|ensembl:ENST00000263368.9(transcript)|go:""GO:0004074""(""biliverdin reductase [NAD(P)+] activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008752""(""FMN reductase [NAD(P)H] activity"")|go:""GO:0030219""(megakaryocyte differentiation)|go:""GO:0035605""(peptidyl-cysteine S-nitrosylase activity)|go:""GO:0042167""(heme catabolic process)|go:""GO:0042602""(""riboflavin reductase (NADPH) activity"")|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0052873""(""FMN reductase (NADPH) activity"")|go:""GO:0052874""(""FMN reductase (NADH) activity"")|go:""GO:0070062""(extracellular exosome)|interpro:IPR016040(""NAD(P)-binding"")|interpro:IPR036291|interpro:IPR051606|rcsb pdb:1HDO|rcsb pdb:1HE2|rcsb pdb:1HE3|rcsb pdb:1HE4|rcsb pdb:1HE5|rcsb pdb:5OOG|rcsb pdb:5OOH|rcsb pdb:6OPL|rcsb pdb:7ER6|rcsb pdb:7ER7|rcsb pdb:7ER8|rcsb pdb:7ER9|rcsb pdb:7ERA|rcsb pdb:7ERB|rcsb pdb:7ERC|rcsb pdb:7ERD|rcsb pdb:7ERE|rcsb pdb:8ELL|rcsb pdb:8ELM|reactome:R-HSA-189483|reactome:R-HSA-9707564|refseq:NP_000704.1|panther:PTHR43355(orthology-group)"	"interpro:IPR013349(Type III secretion system effector YopR)|refseq:NP_395191.1|refseq:NP_857725.1|refseq:NP_857920.1|go:""GO:0005576""(extracellular region)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|rcsb pdb:1Z21|refseq:WP_002212915.1|mint:P68590|interpro:IPR041814"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dAGhnUTdZxBN2cUpArtdmrVdeKw9606	rogid:vLBOGgil8yDmtkZgVzl8ti6IGok632	intact-crc:BED84D37EC060AAE|rigid:WMHcfMsEgyB/mV3SzmubksBHU2A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJJ5	uniprotkb:Q13075	intact:EBI-2842956|uniprotkb:Q0WKJ3	intact:EBI-2874875|uniprotkb:Q99796|uniprotkb:Q13730|uniprotkb:B9EG72|uniprotkb:Q59GI6|uniprotkb:O75857|uniprotkb:E9PHD1|uniprotkb:Q8TDZ4|ensembl:ENSP00000428657.2|ensembl:ENSP00000443944.1|ensembl:ENSP00000484107.1|ensembl:ENSP00000484731.1	psi-mi:hslu_yerpe(display_long)|uniprotkb:hslU(gene name)|psi-mi:hslU(display_short)|uniprotkb:Unfoldase HslU(gene name synonym)|uniprotkb:YPO0105(locus name)|uniprotkb:y0294(locus name)|uniprotkb:YP_0107(locus name)	psi-mi:birc1_human(display_long)|uniprotkb:NAIP(gene name)|psi-mi:NAIP(display_short)|uniprotkb:BIRC1(gene name synonym)|uniprotkb:Neuronal apoptosis inhibitory protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874885|imex:IM-13779-8204	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR004491(Heat shock protein HslU)|interpro:IPR027417|go:""GO:0008233""(peptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0009376""(HslUV protease complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043335""(protein unfolding)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|refseq:WP_002208943.1|refseq:YP_002345195.1|interpro:IPR050052|panther:PTHR48102(orthology-group)"	"dip:DIP-59150N|ensembl:ENSG00000249437.8(gene)|ensembl:ENSG00000278613.4(gene)|ensembl:ENST00000194097.8(transcript)|ensembl:ENST00000517649.6(transcript)|ensembl:ENST00000612328.4(transcript)|ensembl:ENST00000620988.4(transcript)|go:""GO:0002221""(pattern recognition receptor signaling pathway)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0007399""(nervous system development)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0016045""(detection of bacterium)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043027""(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046456""(icosanoid biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0061702""(canonical inflammasome complex)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0072557""(IPAF inflammasome complex)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR028789|interpro:IPR032675|interpro:IPR040535|interpro:IPR053882|mint:Q13075|rcsb pdb:2VM5|rcsb pdb:8FVU|refseq:NP_001333799.1|refseq:NP_004527.2|refseq:NP_075043.1|efo:""Orphanet:83330""|efo:""Orphanet:83418""|efo:""Orphanet:83419""|panther:PTHR46914(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9NL3dzNGgq2JqZd7+stwnNgbDk0632	rogid:ZgyidfeszAIZ7BCEFeUUxF7yOfk9606	intact-crc:20106A887311EC69|rigid:DZr1iv43IbtDF2RNbpHYvL09upo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6W2J9	uniprotkb:A0A2U2H0K6	intact:EBI-950027|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4|ensembl:ENSP00000367705.4|ensembl:ENSP00000384485.3|ensembl:ENSP00000483217.2|ensembl:ENSP00000499892.2|ensembl:ENSP00000505507.1|ensembl:ENSP00000505761.1	intact:EBI-2852628|uniprotkb:A0A3N4B3P8|uniprotkb:Q0WDD4|uniprotkb:Q7CJB1|uniprotkb:A0A384KN94	psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)	psi-mi:a0a2u2h0k6_yerpe(display_long)|uniprotkb:fabB(gene name)|psi-mi:fabB(display_short)|uniprotkb:fabC(gene name synonym)|uniprotkb:YPO2757(locus name)|uniprotkb:3-oxoacyl-[acyl-carrier-protein] synthase I(gene name synonym)|uniprotkb:Beta-ketoacyl-ACP synthase I(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874924|imex:IM-13779-8211	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50009N|efo:""Orphanet:2712""|efo:""Orphanet:457246""|efo:""Orphanet:520""|efo:""Orphanet:568""|ensembl:ENSG00000183337.18(gene)|ensembl:ENST00000378444.9(transcript)|ensembl:ENST00000406200.4(transcript)|ensembl:ENST00000615339.2(transcript)|ensembl:ENST00000672922.2(transcript)|ensembl:ENST00000679513.1(transcript)|ensembl:ENST00000680831.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001835""(blastocyst hatching)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0007507""(heart development)|go:""GO:0030502""(negative regulation of bone mineralization)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042476""(odontogenesis)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060021""(roof of mouth development)|go:""GO:0065001""(specification of axis polarity)|go:""GO:0070171""(negative regulation of tooth mineralization)|go:""GO:0140261""(BCOR complex)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR002110(Ankyrin)|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|interpro:IPR047144|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|rcsb pdb:8HCU|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_016885104.1|panther:PTHR24117(orthology-group)|ensembl:ENST00000342274.8|ensembl:ENSP00000345923.4|ensembl:ENSP00000367705.4|ensembl:ENST00000378455.8|ensembl:ENSP00000367716.4|ensembl:ENST00000397354.7|ensembl:ENSP00000380512.3|ensembl:ENSP00000384485.3|ensembl:ENSP00000483217.2|ensembl:ENSP00000499892.2|ensembl:ENST00000673391.1|ensembl:ENSP00000500446.1|ensembl:ENSP00000505761.1|ensembl:ENSP00000505507.1"	"interpro:IPR018201|rcsb pdb:3OYT|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016039(Thiolase-like)|refseq:WP_002209717.1|interpro:IPR020841|go:""GO:0004315""(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006633""(fatty acid biosynthetic process)|interpro:IPR000794(Beta-ketoacyl synthase)|refseq:YP_002347704.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606	rogid:+3E+vKvbzG7y9HxBalF+akckeKw632	intact-crc:4118E323C66FB9D3|rigid:S7OC8D8IHXeLat9SV0Oh0siE5pY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q00994	uniprotkb:A0A3G5LBG9	intact:EBI-741753|uniprotkb:Q5JQT4|uniprotkb:Q5JQT5|uniprotkb:B2RD17|uniprotkb:D3DXA3|ensembl:ENSP00000361718.1|ensembl:ENSP00000361728.3	intact:EBI-2843337|uniprotkb:Q7ARE7|uniprotkb:Q7BT22|uniprotkb:A0A1U8QL38|uniprotkb:O68742|uniprotkb:Q65AP5|uniprotkb:A0A2S9PDV0	psi-mi:bex3_human(display_long)|uniprotkb:BEX3(gene name)|psi-mi:BEX3(display_short)|uniprotkb:Brain-expressed X-linked protein 3(gene name synonym)|uniprotkb:DXS6984E(gene name synonym)|uniprotkb:NADE(gene name synonym)|uniprotkb:NGFRAP1(gene name synonym)|uniprotkb:Nerve growth factor receptor-associated protein 1(gene name synonym)|uniprotkb:Ovarian granulosa cell 13.0 kDa protein HGR74(gene name synonym)|uniprotkb:p75NTR-associated cell death executor(gene name synonym)	psi-mi:a0a3g5lbg9_yerpe(display_long)|uniprotkb:YPMT1.25c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874917|imex:IM-13779-8209	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055195.1|refseq:NP_996798.1|refseq:NP_996800.1|ensembl:ENSG00000166681.14(gene)|ensembl:ENST00000372635.1(transcript)|ensembl:ENST00000372645.3(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005163""(nerve growth factor receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0140678""(molecular function inhibitor activity)|interpro:IPR007623(Brain expressed X-linked like protein)|interpro:IPR021156|mint:Q00994|reactome:R-HSA-205025|panther:PTHR19430(orthology-group)"	refseq:NP_395361.1|refseq:YP_093902.1|refseq:NP_857661.1|refseq:WP_002211788.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vG0PO2+fbllJpBTuFohFVN9Ar8g9606	rogid:b42FykicLMYhKQ/f+NviSJexojE632	intact-crc:80859D8A892EB9D5|rigid:da3nhfbNIRr7EpJDc4xzacr26Nk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PE45	uniprotkb:Q8TD16	intact:EBI-2874902|uniprotkb:Q7CHG1|uniprotkb:A0A380PMY4|uniprotkb:Q0WH91	intact:EBI-2372628|uniprotkb:O75181|uniprotkb:Q5TBQ2|uniprotkb:Q5TBQ3|uniprotkb:Q96LH2|uniprotkb:Q9BT84|uniprotkb:Q9H561|ensembl:ENSP00000364662.3	psi-mi:a0a2s9pe45_yerpe(display_long)|uniprotkb:nucR(gene name synonym)|uniprotkb:deoR(gene name)|psi-mi:deoR(display_short)|uniprotkb:YPO1322(locus name)	psi-mi:bicd2_human(display_long)|uniprotkb:BICD2(gene name)|psi-mi:BICD2(display_short)|uniprotkb:KIAA0699(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874899|imex:IM-13779-8210	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014036(Bacterial regulatory protein, DeoR)|interpro:IPR001034(Bacterial regulatory protein, DeoR N-terminal)|interpro:IPR018356|refseq:WP_002208770.1|interpro:IPR037171|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR050313|refseq:YP_002346347.1"	"ensembl:ENSG00000185963.14(gene)|ensembl:ENST00000375512.3(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005642""(annulate lamellae)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0015031""(protein transport)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0034452""(dynactin binding)|go:""GO:0051028""(mRNA transport)|go:""GO:0051642""(centrosome localization)|go:""GO:0051959""(dynein light intermediate chain binding)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0070840""(dynein complex binding)|go:""GO:0072385""(minus-end-directed organelle transport along microtubule)|go:""GO:0072393""(microtubule anchoring at microtubule organizing center)|interpro:IPR018477|rcsb pdb:6OFP|rcsb pdb:6PSE|reactome:R-HSA-6811436|refseq:NP_001003800.1|refseq:NP_056065.1|dip:DIP-53426N|efo:""Orphanet:363454""|panther:PTHR31233(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/22	rogid:/FQ7KJuKEQlAgVEvvcq3C/Uk7PE632	rogid:6MPNarWaiURuFhlX154W5E/1kpM9606	intact-crc:4AD65ADB82D8B90A|rigid:qu0pGp0hxO/gubmtLzF9TwtV4G8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UBW5	uniprotkb:Q8CZM8	intact:EBI-2042570|uniprotkb:Q86VV0|uniprotkb:Q9NWK4|uniprotkb:Q9UKN4|uniprotkb:B7Z6F3|uniprotkb:F5H0W4|ensembl:ENSP00000483983.2	intact:EBI-2848309	psi-mi:bin2_human(display_long)|uniprotkb:BIN2(gene name)|psi-mi:BIN2(display_short)|uniprotkb:BRAP1(gene name synonym)|uniprotkb:Breast cancer-associated protein 1(gene name synonym)	psi-mi:q8czm8_yerpe(display_long)|uniprotkb:ptsA(gene name)|psi-mi:ptsA(display_short)|uniprotkb:y3776(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874892|imex:IM-13779-8207	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001276936.1|refseq:NP_001276937.1|refseq:NP_001276938.1|refseq:NP_057377.3|panther:PTHR46514(orthology-group)|ensembl:ENSG00000110934.13(gene)|ensembl:ENST00000615107.6(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002102""(podosome)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042995""(cell projection)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070161""(anchoring junction)|go:""GO:0071800""(podosome assembly)|go:""GO:0097320""(plasma membrane tubulation)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003005(Amphiphysin)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR046984|interpro:IPR048886|rcsb pdb:4AVM|rcsb pdb:4I1Q|reactome:R-HSA-6798695|reactome:R-HSA-9673768"	"interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR018274|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR023151|interpro:IPR006318(Phosphoenolpyruvate-protein phosphotransferase)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR008731(Phosphotransferase system, PEP-utilising enzyme, N-terminal)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|go:""GO:0005737""(cytoplasm)|go:""GO:0008965""(phosphoenolpyruvate-protein phosphotransferase activity)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR040442|interpro:IPR035895|interpro:IPR036618|interpro:IPR036637|interpro:IPR050499"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wD8yD0/ulLv6pt3ICEGRI+G0W0Y9606	rogid:yFrXLYA0rYHKZA16/O8hjY0IDfU632	intact-crc:2B18555876611032|rigid:brmM5jgwbiVMZ2U+H0f2K6G4Bpc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CIZ3	uniprotkb:P55061	intact:EBI-2852946|uniprotkb:Q74UE1	intact:EBI-1045825|uniprotkb:O14938|uniprotkb:Q643A7|uniprotkb:Q96J50|uniprotkb:F8W034|uniprotkb:B2R5M4|ensembl:ENSP00000267115.5|ensembl:ENSP00000378454.4|ensembl:ENSP00000448036.1|ensembl:ENSP00000450158.2	psi-mi:bgal_yerpe(display_long)|uniprotkb:lacZ(gene name)|psi-mi:lacZ(display_short)|uniprotkb:Lactase(gene name synonym)|uniprotkb:YPO1654(locus name)|uniprotkb:y1817(locus name)|uniprotkb:YP_1785(locus name)	psi-mi:bi1_human(display_long)|uniprotkb:Testis-enhanced gene transcript protein(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 6(gene name synonym)|uniprotkb:TMBIM6(gene name)|psi-mi:TMBIM6(display_short)|uniprotkb:BI1(gene name synonym)|uniprotkb:TEGT(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874910|imex:IM-13779-8208	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050347|interpro:IPR008979(Galactose-binding like)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR014718(Glycoside hydrolase-type carbohydrate-binding, subgroup)|interpro:IPR006101(Glycoside hydrolase, family 2)|interpro:IPR023232|interpro:IPR023933|interpro:IPR023230|interpro:IPR004199(Glycoside hydrolase, family 42, domain 5)|interpro:IPR006102(Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich)|interpro:IPR006104(Glycoside hydrolase family 2, carbohydrate-binding)|interpro:IPR006103(Glycoside hydrolase family 2, TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002214048.1|interpro:IPR032312|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004565""(beta-galactosidase activity)|go:""GO:0005990""(lactose catabolic process)|go:""GO:0009341""(beta-galactosidase complex)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036156|refseq:YP_002346664.1|panther:PTHR46323(orthology-group)"	"refseq:NP_001092046.1|refseq:NP_003208.2|ensembl:ENSG00000139644.13(gene)|ensembl:ENST00000267115.10(transcript)|ensembl:ENST00000395006.8(transcript)|ensembl:ENST00000549385.5(transcript)|ensembl:ENST00000552370.5(transcript)|go:""GO:0002638""(negative regulation of immunoglobulin production)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006914""(autophagy)|go:""GO:0010523""(negative regulation of calcium ion transport into cytosol)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0033119""(negative regulation of RNA splicing)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0036483""(neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0060698""(endoribonuclease inhibitor activity)|go:""GO:0060702""(negative regulation of endoribonuclease activity)|go:""GO:1902065""(response to L-glutamate)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903298""(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|interpro:IPR006213(Bax inhibitor 1, conserved site)|interpro:IPR006214(Protein of unknown function UPF0005)|mint:P55061|refseq:XP_005269183.1|panther:PTHR23291(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RFOxfJbd+ZN/lJ/fIfkqbMSwF7w632	rogid:l3wlIZarKWk471gkb6A5Jy/gN/U9606	intact-crc:25CF2BC43F8FE2D5|rigid:uuwF7avmC1YgEqh1TmjgOzw+uB4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q07817	uniprotkb:A0A2S9PFE9	intact:EBI-78035|intact:EBI-28978054|uniprotkb:Q5TE65|uniprotkb:Q92976|uniprotkb:Q5CZ89|uniprotkb:E1P5L6|ensembl:ENSP00000302564.4|ensembl:ENSP00000365230.2|ensembl:ENSP00000389688.2|ensembl:ENSP00000390760.2|ensembl:ENSP00000395545.2|ensembl:ENSP00000401173.2|ensembl:ENSP00000503725.1|ensembl:ENSP00000504237.1|ensembl:ENSP00000504387.1|ensembl:ENSP00000504536.1	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	psi-mi:b2cl1_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874931|imex:IM-13779-8216	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001182.1|refseq:NP_612815.1|panther:PTHR11256(orthology-group)|refseq:XP_011527266.1|refseq:NP_001304848.1|refseq:NP_001304849.1|refseq:NP_001304850.1|refseq:NP_001309168.1|refseq:NP_001309169.1|refseq:NP_001309171.1|refseq:XP_016883482.1|dip:DIP-30916N|ensembl:ENSP00000302564.4|ensembl:ENST00000376055.9|ensembl:ENSP00000365223.4|ensembl:ENSP00000365230.2|ensembl:ENSP00000390760.2|ensembl:ENST00000422920.2|ensembl:ENSP00000411252.2|ensembl:ENSP00000401173.2|ensembl:ENSP00000389688.2|ensembl:ENSP00000395545.2|ensembl:ENSP00000503725.1|ensembl:ENSP00000504536.1|ensembl:ENSP00000504387.1|ensembl:ENSP00000504237.1|ensembl:ENSG00000171552.14(gene)|ensembl:ENST00000307677.5(transcript)|ensembl:ENST00000376062.6(transcript)|ensembl:ENST00000420488.6(transcript)|ensembl:ENST00000434194.2(transcript)|ensembl:ENST00000439267.2(transcript)|ensembl:ENST00000456404.6(transcript)|ensembl:ENST00000676582.1(transcript)|ensembl:ENST00000676942.1(transcript)|ensembl:ENST00000677194.1(transcript)|ensembl:ENST00000678563.1(transcript)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006897""(endocytosis)|go:""GO:0007281""(germ cell development)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008584""(male gonad development)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0008637""(apoptotic mitochondrial changes)|go:""GO:0009566""(fertilization)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0015267""(channel activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032946""(positive regulation of mononuclear cell proliferation)|go:""GO:0034097""(response to cytokine)|go:""GO:0035234""(ectopic germ cell programmed cell death)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0044565""(dendritic cell proliferation)|go:""GO:0046898""(response to cycloheximide)|go:""GO:0046902""(regulation of mitochondrial membrane permeability)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0051093""(negative regulation of developmental process)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071312""(cellular response to alkaloid)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071839""(apoptotic process in bone marrow cell)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0097048""(dendritic cell apoptotic process)|go:""GO:0097136""(Bcl-2 family protein complex)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:1900118""(negative regulation of execution phase of apoptosis)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:2000242""(negative regulation of reproductive process)|go:""GO:2000669""(negative regulation of dendritic cell apoptotic process)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|interpro:IPR046371|mint:Q07817|rcsb pdb:1BXL|rcsb pdb:1G5J|rcsb pdb:1LXL|rcsb pdb:1MAZ|rcsb pdb:1R2D|rcsb pdb:1R2E|rcsb pdb:1R2G|rcsb pdb:1R2H|rcsb pdb:1R2I|rcsb pdb:1YSG|rcsb pdb:1YSI|rcsb pdb:1YSN|rcsb pdb:2B48|rcsb pdb:2LP8|rcsb pdb:2LPC|rcsb pdb:2M03|rcsb pdb:2M04|rcsb pdb:2ME8|rcsb pdb:2ME9|rcsb pdb:2MEJ|rcsb pdb:2O1Y|rcsb pdb:2O2M|rcsb pdb:2O2N|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:2YJ1|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:2YXJ|rcsb pdb:3CVA|rcsb pdb:3FDL|rcsb pdb:3FDM|rcsb pdb:3INQ|rcsb pdb:3IO8|rcsb pdb:3PL7|rcsb pdb:3QKD|rcsb pdb:3R85|rcsb pdb:3SP7|rcsb pdb:3SPF|rcsb pdb:3WIZ|rcsb pdb:3ZK6|rcsb pdb:3ZLN|rcsb pdb:3ZLO|rcsb pdb:3ZLR|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4AQ3|rcsb pdb:4BPK|rcsb pdb:4C52|rcsb pdb:4C5D|rcsb pdb:4CIN|rcsb pdb:4EHR|rcsb pdb:4HNJ|rcsb pdb:4IEH|rcsb pdb:4PPI|rcsb pdb:4QVE|rcsb pdb:4QVF|rcsb pdb:4QVX|rcsb pdb:4TUH|rcsb pdb:4Z9V|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5B1Z|rcsb pdb:5C3G|rcsb pdb:5FMJ|rcsb pdb:5FMK|rcsb pdb:5VAY|rcsb pdb:5VX3|rcsb pdb:6BF2|rcsb pdb:6DCN|rcsb pdb:6DCO|rcsb pdb:6F46|rcsb pdb:6HJL|rcsb pdb:6IJQ|rcsb pdb:6LHD|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:6RNU|rcsb pdb:6ST2|rcsb pdb:6UVC|rcsb pdb:6UVD|rcsb pdb:6UVE|rcsb pdb:6UVF|rcsb pdb:6UVG|rcsb pdb:6UVH|rcsb pdb:6VWC|rcsb pdb:6X7I|rcsb pdb:6YLI|rcsb pdb:6ZHC|rcsb pdb:7CA4|rcsb pdb:7JGV|rcsb pdb:7JGW|rcsb pdb:7LH7|rcsb pdb:7XGF|rcsb pdb:7XGG|rcsb pdb:7Y8D|rcsb pdb:7YAA|rcsb pdb:8FY0|rcsb pdb:8IQK|rcsb pdb:8IQL|rcsb pdb:8U27|rcsb pdb:8VWX|rcsb pdb:8VWZ|rcsb pdb:8VXM|rcsb pdb:8VXN|rcsb pdb:8WLS|rcsb pdb:8XP5|rcsb pdb:9AQZ|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9648002|reactome:R-HSA-9692913|reactome:R-HSA-9702518|reactome:R-HSA-9818030"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	intact-crc:7A9C6651FF2969E0|rigid:2AvkcTGGREC7judRYHFPGrv70as	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NYF8	uniprotkb:Q8ZBC2	intact:EBI-437804|ensembl:ENSP00000435210.1|uniprotkb:Q86WY0|uniprotkb:Q14673|uniprotkb:Q86WU6|uniprotkb:B7ZM58|uniprotkb:A2RU75|uniprotkb:E1P586	intact:EBI-2851492|uniprotkb:Q0WBF3	psi-mi:bclf1_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 1(gene name synonym)|uniprotkb:BCLAF1(gene name)|psi-mi:BCLAF1(display_short)|uniprotkb:BTF(gene name synonym)|uniprotkb:KIAA0164(gene name synonym)	psi-mi:if2_yerpe(display_long)|uniprotkb:infB(gene name)|psi-mi:infB(display_short)|uniprotkb:YPO3496(locus name)|uniprotkb:y0688(locus name)|uniprotkb:YP_0587(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874945|imex:IM-13779-8215	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000029363.17(gene)|ensembl:ENST00000531224.6(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0016592""(mediator complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR029199|mint:Q9NYF8|rcsb pdb:7RJN|rcsb pdb:7RJR|refseq:NP_001070908.1|refseq:NP_001070909.1|refseq:NP_055554.1|refseq:NP_001287967.1|panther:PTHR15268(orthology-group)"	"refseq:WP_002223151.1|interpro:IPR044145|interpro:IPR009061(Putative DNA binding)|interpro:IPR013575(Initiation factor 2 associated region, bacterial)|interpro:IPR006847(Translation initiation factor IF-2, N-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000178(Initiation factor 2)|interpro:IPR023115|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR015760(Translation initiation factor 2 related)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR036925|interpro:IPR053905|refseq:YP_002348385.1|panther:PTHR43381(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v6qbjyjKVCv0B/olkjQfTPKWqBw9606	rogid:8Lhp4NihTUjn3nGZLA2K6kHbXg8632	intact-crc:7A349795C6DE46CE|rigid:8PtKybzwU2jNsqRNUbeCUdEbcHg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10415	uniprotkb:Q0WGQ5	intact:EBI-77694|uniprotkb:P10416|uniprotkb:Q13842|uniprotkb:Q16197|uniprotkb:C9JHD5|ensembl:ENSP00000329623.3|ensembl:ENSP00000381185.1	intact:EBI-2853517|uniprotkb:Q74VA6|uniprotkb:Q7CHR0	psi-mi:bcl2_human(display_long)|uniprotkb:BCL2(gene name)|psi-mi:BCL2(display_short)	psi-mi:q0wgq5_yerpe(display_long)|uniprotkb:YPO1517(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874959|imex:IM-13779-8214	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11256(orthology-group)|efo:""Orphanet:480541""|efo:""Orphanet:545""|efo:""Orphanet:98839""|dip:DIP-1043N|rcsb pdb:2W3L|rcsb pdb:2XA0|rcsb pdb:4AQ3|rcsb pdb:4IEH|rcsb pdb:4LVT|rcsb pdb:4LXD|rcsb pdb:4MAN|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5FCG|rcsb pdb:5JSN|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6GL8|rcsb pdb:6IWB|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:7LHB|rcsb pdb:7Y90|rcsb pdb:7YA5|rcsb pdb:8FY1|rcsb pdb:8FY2|rcsb pdb:8HLL|rcsb pdb:8HLM|rcsb pdb:8HLN|rcsb pdb:8HOG|rcsb pdb:8HOH|rcsb pdb:8HOI|rcsb pdb:8HTR|rcsb pdb:8HTS|rcsb pdb:8IQL|rcsb pdb:8U27|rcsb pdb:8VWX|rcsb pdb:8VWZ|rcsb pdb:8VXM|rcsb pdb:8VXN|ensembl:ENSG00000171791.14(gene)|ensembl:ENST00000333681.5(transcript)|ensembl:ENST00000398117.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001503""(ossification)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0001656""(metanephros development)|go:""GO:0001658""(branching involved in ureteric bud morphogenesis)|go:""GO:0001662""(behavioral fear response)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001783""(B cell apoptotic process)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0001952""(regulation of cell-matrix adhesion)|go:""GO:0002020""(protease binding)|go:""GO:0002320""(lymphoid progenitor cell differentiation)|go:""GO:0002326""(B cell lineage commitment)|go:""GO:0002903""(negative regulation of B cell apoptotic process)|go:""GO:0002931""(response to ischemia)|go:""GO:0003014""(renal system process)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006582""(melanin metabolic process)|go:""GO:0006808""(regulation of nitrogen utilization)|go:""GO:0006914""(autophagy)|go:""GO:0006915""(apoptotic process)|go:""GO:0006959""(humoral immune response)|go:""GO:0006974""(DNA damage response)|go:""GO:0007015""(actin filament organization)|go:""GO:0007409""(axonogenesis)|go:""GO:0007565""(female pregnancy)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008584""(male gonad development)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0008631""(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:""GO:0009314""(response to radiation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010039""(response to iron ion)|go:""GO:0010224""(response to UV-B)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010523""(negative regulation of calcium ion transport into cytosol)|go:""GO:0010559""(regulation of glycoprotein biosynthetic process)|go:""GO:0014031""(mesenchymal cell development)|go:""GO:0014042""(positive regulation of neuron maturation)|go:""GO:0014909""(smooth muscle cell migration)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0015267""(channel activity)|go:""GO:0016020""(membrane)|go:""GO:0016248""(channel inhibitor activity)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0022612""(gland morphogenesis)|go:""GO:0022898""(regulation of transmembrane transporter activity)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030318""(melanocyte differentiation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031103""(axon regeneration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0032835""(glomerulus development)|go:""GO:0032848""(negative regulation of cellular pH reduction)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033028""(myeloid cell apoptotic process)|go:""GO:0033033""(negative regulation of myeloid cell apoptotic process)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033687""(osteoblast proliferation)|go:""GO:0033689""(negative regulation of osteoblast proliferation)|go:""GO:0034097""(response to cytokine)|go:""GO:0035094""(response to nicotine)|go:""GO:0035265""(organ growth)|go:""GO:0040018""(positive regulation of multicellular organism growth)|go:""GO:0042100""(B cell proliferation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042551""(neuron maturation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043209""(myelin sheath)|go:""GO:0043375""(CD8-positive, alpha-beta T cell lineage commitment)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0043583""(ear development)|go:""GO:0045069""(regulation of viral genome replication)|go:""GO:0045636""(positive regulation of melanocyte differentiation)|go:""GO:0046666""(retinal cell programmed cell death)|go:""GO:0046671""(negative regulation of retinal cell programmed cell death)|go:""GO:0046902""(regulation of mitochondrial membrane permeability)|go:""GO:0046930""(pore complex)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0048546""(digestive tract morphogenesis)|go:""GO:0048599""(oocyte development)|go:""GO:0048741""(skeletal muscle fiber development)|go:""GO:0048743""(positive regulation of skeletal muscle fiber development)|go:""GO:0048753""(pigment granule organization)|go:""GO:0048864""(stem cell development)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051881""(regulation of mitochondrial membrane potential)|go:""GO:0051902""(negative regulation of mitochondrial depolarization)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0060402""(calcium ion transport into cytosol)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070231""(T cell apoptotic process)|go:""GO:0070233""(negative regulation of T cell apoptotic process)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0097048""(dendritic cell apoptotic process)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097138""(BAD-BCL-2 complex)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1904036""(negative regulation of epithelial cell apoptotic process)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2000669""(negative regulation of dendritic cell apoptotic process)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2001234""(negative regulation of apoptotic signaling pathway)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013278(Apoptosis regulator, Bcl-2)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|interpro:IPR046371|mint:P10415|rcsb pdb:1G5M|rcsb pdb:1GJH|rcsb pdb:1YSW|rcsb pdb:2O21|rcsb pdb:2O22|rcsb pdb:2O2F|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9018519|reactome:R-HSA-9634638|reactome:R-HSA-9818030|reactome:R-HSA-9824594|refseq:NP_000624.2|refseq:NP_000648.2"	"interpro:IPR050555|interpro:IPR025997|interpro:IPR028082|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002346533.1|panther:PTHR30036(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/06	rogid:XC215VuR7Wf2ACXOm1pTyyuimSU9606	rogid:qnuiW6B7FZ3gckfa7i2/HzKZAI8632	intact-crc:76DE7AECA890D549|rigid:Wq/M334+z3SvljIB93T0kuaZ7yU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZED8	uniprotkb:Q9NYF8	intact:EBI-2840186|uniprotkb:Q0WET1	intact:EBI-437804|ensembl:ENSP00000435210.1|uniprotkb:Q86WY0|uniprotkb:Q14673|uniprotkb:Q86WU6|uniprotkb:B7ZM58|uniprotkb:A2RU75|uniprotkb:E1P586	psi-mi:rnb_yerpe(display_long)|uniprotkb:rnb(gene name)|psi-mi:rnb(display_short)|uniprotkb:Exoribonuclease II(gene name synonym)|uniprotkb:YPO2235(locus name)|uniprotkb:y2077(locus name)|uniprotkb:YP_2034(locus name)	psi-mi:bclf1_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 1(gene name synonym)|uniprotkb:BCLAF1(gene name)|psi-mi:BCLAF1(display_short)|uniprotkb:BTF(gene name synonym)|uniprotkb:KIAA0164(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874938|imex:IM-13779-8212	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR022966|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011804(Ribonuclease II, bacterial)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008859""(exoribonuclease II activity)|refseq:WP_002210605.1|interpro:IPR001900(Ribonuclease II and R)|refseq:YP_002347207.1|interpro:IPR050180|panther:PTHR23355(orthology-group)"	"ensembl:ENSG00000029363.17(gene)|ensembl:ENST00000531224.6(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0016592""(mediator complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR029199|mint:Q9NYF8|rcsb pdb:7RJN|rcsb pdb:7RJR|refseq:NP_001070908.1|refseq:NP_001070909.1|refseq:NP_055554.1|refseq:NP_001287967.1|panther:PTHR15268(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8bPsungEsr2YreZsZg9IgHPm9uI632	rogid:v6qbjyjKVCv0B/olkjQfTPKWqBw9606	intact-crc:E071C095C481D49D|rigid:JL+My3aKiETpq6s7FsDJ4Gqak28	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P41182	uniprotkb:Q8D184	intact:EBI-765407|uniprotkb:A7E241|ensembl:ENSP00000232014.4|ensembl:ENSP00000384371.2|uniprotkb:D3DNV5|uniprotkb:B8PSA7	intact:EBI-2848181|uniprotkb:Q74XL8	psi-mi:bcl6_human(display_long)|uniprotkb:Zinc finger protein 51(gene name synonym)|uniprotkb:Protein LAZ-3(gene name synonym)|uniprotkb:B-cell lymphoma 5 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 27(gene name synonym)|uniprotkb:BCL6(gene name)|psi-mi:BCL6(display_short)|uniprotkb:BCL5(gene name synonym)|uniprotkb:LAZ3(gene name synonym)|uniprotkb:ZBTB27(gene name synonym)|uniprotkb:ZNF51(gene name synonym)	psi-mi:q8d184_yerpe(display_long)|uniprotkb:aroF(gene name)|psi-mi:aroF(display_short)|uniprotkb:NCTC5923_01037(orf name)|uniprotkb:YP_0398(locus name)|uniprotkb:y0903(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874952|imex:IM-13779-8213	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:6ZBU|rcsb pdb:7BDE|rcsb pdb:7LWE|rcsb pdb:7LWF|rcsb pdb:7LWG|rcsb pdb:7LZQ|rcsb pdb:7LZR|rcsb pdb:7LZS|rcsb pdb:7OKD|rcsb pdb:7OKE|rcsb pdb:7OKF|rcsb pdb:7OKG|rcsb pdb:7OKH|rcsb pdb:7OKI|rcsb pdb:7OKJ|rcsb pdb:7OKK|rcsb pdb:7OKL|rcsb pdb:7OKM|rcsb pdb:7Q7R|rcsb pdb:7Q7S|rcsb pdb:7Q7T|rcsb pdb:7Q7U|rcsb pdb:7Q7V|rcsb pdb:7QK0|rcsb pdb:7RUW|rcsb pdb:7RUX|rcsb pdb:7RUY|rcsb pdb:7RUZ|rcsb pdb:7RV0|rcsb pdb:7RV1|rcsb pdb:7RV2|rcsb pdb:7RV3|rcsb pdb:7RV4|ensembl:ENSG00000113916.18(gene)|ensembl:ENST00000232014.8(transcript)|ensembl:ENST00000406870.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001161""(intronic transcription regulatory region sequence-specific DNA binding)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0001953""(negative regulation of cell-matrix adhesion)|go:""GO:0002317""(plasma cell differentiation)|go:""GO:0002467""(germinal center formation)|go:""GO:0002634""(regulation of germinal center formation)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0002903""(negative regulation of B cell apoptotic process)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008104""(protein localization)|go:""GO:0021859""(pyramidal neuron differentiation)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032764""(negative regulation of mast cell cytokine production)|go:""GO:0032945""(negative regulation of mononuclear cell proliferation)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0042092""(type 2 immune response)|go:""GO:0042100""(B cell proliferation)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0042382""(paraspeckles)|go:""GO:0042802""(identical protein binding)|rcsb pdb:2EN2|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043380""(regulation of memory T cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045064""(T-helper 2 cell differentiation)|go:""GO:0045591""(positive regulation of regulatory T cell differentiation)|go:""GO:0045595""(regulation of cell differentiation)|go:""GO:0045629""(negative regulation of T-helper 2 cell differentiation)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048289""(isotype switching to IgE isotypes)|go:""GO:0048294""(negative regulation of isotype switching to IgE isotypes)|go:""GO:0048821""(erythrocyte development)|go:""GO:0048870""(cell motility)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050776""(regulation of immune response)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1900099""(negative regulation of plasma cell differentiation)|go:""GO:1903464""(negative regulation of mitotic cell cycle DNA replication)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000147""(positive regulation of cell motility)|go:""GO:2000773""(negative regulation of cellular senescence)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P41182|rcsb pdb:1R28|rcsb pdb:1R29|rcsb pdb:1R2B|rcsb pdb:2EOS|rcsb pdb:2LCE|rcsb pdb:2YRM|rcsb pdb:3BIM|rcsb pdb:3E4U|rcsb pdb:3LBZ|rcsb pdb:4CP3|rcsb pdb:4U2M|rcsb pdb:5H7G|rcsb pdb:5H7H|rcsb pdb:5MW2|rcsb pdb:5MW6|rcsb pdb:5MWD|rcsb pdb:5N1X|rcsb pdb:5N1Z|rcsb pdb:5N20|rcsb pdb:5N21|rcsb pdb:5X4M|rcsb pdb:5X4N|rcsb pdb:5X4O|rcsb pdb:5X4P|rcsb pdb:5X4Q|rcsb pdb:5X9O|rcsb pdb:5X9P|rcsb pdb:6C3L|rcsb pdb:6C3N|rcsb pdb:6CQ1|rcsb pdb:6EW6|rcsb pdb:6EW7|rcsb pdb:6EW8|rcsb pdb:6TBT|rcsb pdb:6TCJ|rcsb pdb:6TOF|rcsb pdb:6TOG|rcsb pdb:6TOH|rcsb pdb:6TOI|rcsb pdb:6TOJ|rcsb pdb:6TOK|rcsb pdb:6TOL|rcsb pdb:6TOM|rcsb pdb:6TON|rcsb pdb:6TOO|rcsb pdb:6XMX|rcsb pdb:6XWF|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:7RV5|rcsb pdb:7RV6|rcsb pdb:7RV7|rcsb pdb:7RV8|rcsb pdb:7RV9|rcsb pdb:7T0S|rcsb pdb:7T0T|rcsb pdb:7T0U|rcsb pdb:7ZWN|rcsb pdb:7ZWO|rcsb pdb:7ZWP|rcsb pdb:7ZWQ|rcsb pdb:7ZWR|rcsb pdb:7ZWS|rcsb pdb:7ZWT|rcsb pdb:7ZWU|rcsb pdb:7ZWV|rcsb pdb:7ZWW|rcsb pdb:7ZWX|rcsb pdb:7ZWY|rcsb pdb:7ZWZ|rcsb pdb:8AS9|rcsb pdb:8C78|reactome:R-HSA-6785807|reactome:R-HSA-6803205|reactome:R-HSA-9614657|refseq:NP_001124317.1|refseq:NP_001128210.1|refseq:NP_001697.2|refseq:XP_005247751.1|refseq:XP_011511364.1|dip:DIP-2651N|efo:""Orphanet:480541""|efo:""Orphanet:545""|efo:""Orphanet:98838""|efo:""Orphanet:98839""|panther:PTHR24399(orthology-group)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR006218(DAHP synthetase I/KDSA)|interpro:IPR006219(DHAP synthase, class 1)|go:""GO:0003849""(3-deoxy-7-phosphoheptulonate synthase activity)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0009073""(aromatic amino acid family biosynthetic process)|go:""GO:0009423""(chorismate biosynthetic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JJg3jvMnpVMpgsrrkIqZ2qinZCQ9606	rogid:4L95qW4AbphJFnq2t9Za1RWY2IQ632	intact-crc:DCF224007FDBB538|rigid:ryn12GXfD706bNUn34T3nUE+sZ4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46379	uniprotkb:Q8D064	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2874997|uniprotkb:Q74VG2	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:q8d064_yerpe(display_long)|uniprotkb:fabG(gene name)|psi-mi:fabG(display_short)|uniprotkb:fabG6(gene name synonym)|uniprotkb:YP_1348(locus name)|uniprotkb:y2713(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874994|imex:IM-13779-8221	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|go:""GO:0016491""(oxidoreductase activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:IGQhUzaKSUd8+b2KxBDTnR+5OUQ632	intact-crc:4E5120C03A0C4CC6|rigid:TTXz1B2u52P1FsbZr9esEoD2Qy8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIC5	uniprotkb:P46379	intact:EBI-2858331|uniprotkb:Q0WJ86	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:uxab_yerpe(display_long)|uniprotkb:uxaB(gene name)|psi-mi:uxaB(display_short)|uniprotkb:Tagaturonate dehydrogenase(gene name synonym)|uniprotkb:Tagaturonate reductase(gene name synonym)|uniprotkb:YPO0580(locus name)|uniprotkb:y3599(locus name)|uniprotkb:YP_2900(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874973|imex:IM-13779-8220	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR023668|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR013118(Mannitol dehydrogenase, C-terminal)|interpro:IPR013131(Mannitol dehydrogenase, N-terminal)|refseq:WP_002210409.1|go:""GO:0005829""(cytosol)|go:""GO:0008926""(mannitol-1-phosphate 5-dehydrogenase activity)|go:""GO:0009026""(tagaturonate reductase activity)|go:""GO:0019592""(mannitol catabolic process)|go:""GO:0019698""(D-galacturonate catabolic process)|interpro:IPR036291|refseq:YP_002345652.1|panther:PTHR30524(orthology-group)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PyqKR9KbcVlhb9JsQra1Qvptw6Y632	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:C1607A7E3A437CD9|rigid:HI4LI7gnvHPdhC5fp4QCUrPwM28	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VBG2	uniprotkb:P46379	intact:EBI-2849663	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:a0a6b3vbg2_yerpe(display_long)|uniprotkb:yapB(gene name)|psi-mi:yapB(display_short)|uniprotkb:y1345(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874987|imex:IM-13779-8219	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|uniprotkb:A0A6B3T6Y5(uniprot-removed-ac)|go:""GO:0019867""(outer membrane)|interpro:IPR051551"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jNPx4rqCv9bEZelj7jbp42kW+NY632	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:3B9B12873BCBF9A4|rigid:xnKcSfcF93j8Si5bOnfR/kZLQSI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZV1	uniprotkb:Q9H165	intact:EBI-2843995	intact:EBI-765567|uniprotkb:Q86W14|uniprotkb:Q8WU92|uniprotkb:Q96JL6|uniprotkb:Q9H163|uniprotkb:Q9H164|uniprotkb:Q9H3G9|uniprotkb:Q9NWA7|uniprotkb:D6W5D7|ensembl:ENSP00000496168.1|uniprotkb:Q66LN6	psi-mi:q8czv1_yerpe(display_long)|uniprotkb:y3335(locus name)	psi-mi:bc11a_human(display_long)|uniprotkb:B-cell CLL/lymphoma 11A(gene name synonym)|uniprotkb:COUP-TF-interacting protein 1(gene name synonym)|uniprotkb:Ecotropic viral integration site 9 protein homolog(gene name synonym)|uniprotkb:BCL11A(gene name)|psi-mi:BCL11A(display_short)|uniprotkb:CTIP1(gene name synonym)|uniprotkb:EVI9(gene name synonym)|uniprotkb:KIAA1809(gene name synonym)|uniprotkb:ZNF856(gene name synonym)|uniprotkb:Zinc finger protein 856(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874966|imex:IM-13779-8217	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR021307	"ensembl:ENSG00000119866.22(gene)|ensembl:ENST00000642384.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001067""(transcription regulatory region nucleic acid binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016925""(protein sumoylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030517""(negative regulation of axon extension)|go:""GO:0032463""(negative regulation of protein homooligomerization)|go:""GO:0042382""(paraspeckles)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048671""(negative regulation of collateral sprouting)|go:""GO:0048672""(positive regulation of collateral sprouting)|go:""GO:0050773""(regulation of dendrite development)|go:""GO:0098794""(postsynapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1903860""(negative regulation of dendrite extension)|go:""GO:1904800""(negative regulation of neuron remodeling)|go:""GO:1905232""(cellular response to L-glutamate)|go:""GO:2000171""(negative regulation of dendrite development)|go:""GO:2000173""(negative regulation of branching morphogenesis of a nerve)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR051497|mint:Q9H165|rcsb pdb:5VTB|rcsb pdb:6KI6|rcsb pdb:6U9Q|rcsb pdb:8DTN|rcsb pdb:8DTU|rcsb pdb:8THO|rcsb pdb:8TLO|rcsb pdb:9BV0|reactome:R-HSA-9700645|reactome:R-HSA-9725370|refseq:NP_060484.2|refseq:NP_075044.2|refseq:NP_612569.1|refseq:XP_011531211.1|refseq:XP_016859823.1|dip:DIP-45629N|efo:""Orphanet:251380""|efo:""Orphanet:619233""|panther:PTHR45993(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/17	rogid:mvlSMRwfbr0qayRobyN7vmxNk50632	rogid:xASsLQWykg/7ZpyjLsQP8GlQ/H09606	intact-crc:0A287C2954360AF8|rigid:7eYE5k5BLsNaSjOtZuDRzOFE19c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46379	uniprotkb:Q9F290	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2848917|uniprotkb:Q7CJX2|uniprotkb:Q74VW8|uniprotkb:A0A384LNI0|uniprotkb:A0A1U8QEG5|uniprotkb:A0A2U2GUS9	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:q9f290_yerpe(display_long)|uniprotkb:yapC(gene name)|psi-mi:yapC(display_short)|uniprotkb:YPO2796(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2874980|imex:IM-13779-8218	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)|interpro:IPR012332(Phage P22 tailspike)|refseq:WP_002209752.1|go:""GO:0009279""(cell outer membrane)|interpro:IPR036709|refseq:YP_002347738.1|interpro:IPR051551|panther:PTHR35037(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:pdr4YGdh7vzVjMHR+QhHJFQ2SUE632	intact-crc:7BE9A8FF4A7CC09D|rigid:vwgj+qWGd82ZeUV9xI6guGiHxq0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZY0	uniprotkb:P46379	intact:EBI-2843763	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:q8czy0_yerpe(display_long)|uniprotkb:y3182(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875006|imex:IM-13779-8226	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR041954|interpro:IPR050612"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Y5d3heMPjpe23bUutQ9OKW+v73g632	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:09F118973B6BEA9A|rigid:Le0c0d+O42F3/r3u9QikZa9+OZc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46379	uniprotkb:A0A454Y4S5	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2842434|uniprotkb:Q74PE1|uniprotkb:Q0W9W9|uniprotkb:Q7CFQ1|uniprotkb:A0A384L034	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:a0a454y4s5_yerpe(display_long)|uniprotkb:cheM(gene name)|psi-mi:cheM(display_short)|uniprotkb:tar(gene name synonym)|uniprotkb:YPO4062(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875036|imex:IM-13779-8223	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|refseq:WP_002209615.1|interpro:IPR032255|refseq:YP_002348919.1|interpro:IPR051310|panther:PTHR43531(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:9q/B+fA+5z2go4RyqrxgvIHLpyk632	intact-crc:C0BA4976F68C97E7|rigid:lIaI/EolOygSDeyFpgtrFRgKNoU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W5A8	uniprotkb:P46379	intact:EBI-2875025|uniprotkb:Q74TQ0|uniprotkb:Q0WEL1|uniprotkb:Q7CII5|uniprotkb:A0A5P8YGR5|uniprotkb:A0A384LGY9	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:a0a0h2w5a8_yerpe(display_long)|uniprotkb:YPO2310(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875029|imex:IM-13779-8225	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001333(Peptidase M32, carboxypeptidase Taq metallopeptidase)|refseq:WP_002211014.1|go:""GO:0004181""(metallocarboxypeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347277.1"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2iDB/wxrmRr2QnH+CsqCeDrsU0o632	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:3F9420F9217A0DF8|rigid:aZpksP6HKdGx2/W3RV4iPV5kcVs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WAY7	uniprotkb:P46379	intact:EBI-2875016|uniprotkb:Q74PL8|uniprotkb:Q7CL65|uniprotkb:A0A5P8YK51|uniprotkb:A0A0H2W9J4	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:q0way7_yerpe(display_long)|uniprotkb:envB(gene name)|psi-mi:envB(display_short)|uniprotkb:mreB(gene name synonym)|uniprotkb:rodY(gene name synonym)|uniprotkb:YPO3665(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875013|imex:IM-13779-8222	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000902""(cell morphogenesis)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008360""(regulation of cell shape)|interpro:IPR043129|interpro:IPR004753(Cell shape determining protein MreB/Mrl)|refseq:YP_002348551.1|refseq:WP_002228205.1"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xwdBXM3n+1+xSAHpWtyTKWUf4io632	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:890237A8B2FD113D|rigid:i8fs6F2ctQLn6vJPtKJYQGnstww	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CIS2	uniprotkb:P46379	intact:EBI-2864684|uniprotkb:Q74TI4	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:purr_yerpe(display_long)|uniprotkb:purR(gene name)|psi-mi:purR(display_short)|uniprotkb:Pur regulon repressor(gene name synonym)|uniprotkb:Purine nucleotide synthesis repressor(gene name synonym)|uniprotkb:YPO2387(locus name)|uniprotkb:y1950(locus name)|uniprotkb:YP_2173(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875043|imex:IM-13779-8224	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000843(Bacterial regulatory protein, LacI)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR023588|interpro:IPR028082|refseq:WP_002210943.1|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002347353.1|interpro:IPR046335|panther:PTHR30146(orthology-group)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dzdla2mdqawR0H2DRHviks1p1L0632	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:34BB2F6EE4D04F47|rigid:guHDTcQEsRPXwspw8+ghM5mYd1M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ16	uniprotkb:P46379	intact:EBI-2841852|uniprotkb:Q0WJZ3	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:lexa_yerpe(display_long)|uniprotkb:lexA(gene name)|psi-mi:lexA(display_short)|uniprotkb:YPO0314(locus name)|uniprotkb:y0572(locus name)|uniprotkb:YP_0470(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875064|imex:IM-13779-8228	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039418|interpro:IPR006199(LexA DNA-binding region)|interpro:IPR006200(Peptidase S24, LexA repressor)|interpro:IPR006197(Peptidase S24, LexA/MucA/RumA/RuvA)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0009432""(SOS response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002345395.1|refseq:WP_002209090.1|interpro:IPR036286|interpro:IPR036388|interpro:IPR036390|interpro:IPR050077|panther:PTHR33516(orthology-group)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1RBPmARbsfVEavq4/r0MVDBH/Og632	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:22B5E97E3AB43460|rigid:+wqosas4Ycxakcc5dxl1DaGCYbU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46379	uniprotkb:Q7ARH3	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2849426|uniprotkb:A0A384KLR8|uniprotkb:O68711|uniprotkb:Q74YV0|uniprotkb:A0A0H2W092|uniprotkb:A0A2U2GVE2	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:q7arh3_yerpe(display_long)|uniprotkb:tnpA(gene name)|psi-mi:tnpA(display_short)|uniprotkb:YPCD1.90c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875057|imex:IM-13779-8230	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"refseq:NP_857769.1|interpro:IPR002513(Transposase, Tn3)|refseq:NP_395219.1|interpro:IPR025296|interpro:IPR047653|refseq:WP_002213256.1|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:00nBYkSaVEOjkb6Bm6Lk/llhQRc632	intact-crc:2D4A9E8CE48B7AFE|rigid:Rz39HaC/kO/zFhLsqbFPLDPIFmg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCQ2	uniprotkb:P46379	intact:EBI-2850142|uniprotkb:Q0WCY7	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:pur4_yerpe(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:YPO2921(locus name)|uniprotkb:YP_2536(locus name)|uniprotkb:y1309(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875050|imex:IM-13779-8227	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR029062|refseq:WP_002211561.1|interpro:IPR040707|go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609|refseq:YP_002347851.1|panther:PTHR10099(orthology-group)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8JTbD5hWDWC5PK7sHtiOwqqdyHs632	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:ECC3107E3BD0F4E0|rigid:TpVL2khbuI0vKmsxsifujPBjUCo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BA87	uniprotkb:P35613	intact:EBI-2849383|uniprotkb:Q74PH8|uniprotkb:A0A0H2W8Y4|uniprotkb:Q7CL39|uniprotkb:A0A384L9C4	intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769.3	psi-mi:a0a3n4ba87_yerpe(display_long)|uniprotkb:ISU59_19965(orf name)|uniprotkb:YPO3618(locus name)	psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875078|imex:IM-13779-8231	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004104(Oxidoreductase, C-terminal)|interpro:IPR000683(Oxidoreductase, N-terminal)|refseq:WP_002210025.1|go:""GO:0000166""(nucleotide binding)|go:""GO:0005829""(cytosol)|go:""GO:0017000""(antibiotic biosynthetic process)|go:""GO:0102497""(""scyllo-inositol dehydrogenase (NADP+) activity"")|interpro:IPR036291|refseq:YP_002348503.1|interpro:IPR051317|panther:PTHR43708(orthology-group)"	"refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|ensembl:ENSG00000172270.22(gene)|ensembl:ENST00000333511.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0003407""(neural retina development)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007566""(embryo implantation)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045296""(cadherin binding)|go:""GO:0045494""(photoreceptor cell maintenance)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0046689""(response to mercury ion)|go:""GO:0046697""(decidualization)|go:""GO:0051591""(response to cAMP)|go:""GO:0061154""(endothelial tube morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:1904466""(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:3QR2|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|rcsb pdb:7DAA|rcsb pdb:7DCE|rcsb pdb:7XY8|rcsb pdb:8XEJ|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-9749641|refseq:XP_016882662.1|dip:DIP-50310N|panther:PTHR10075(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oAKjFkWV9yeIL0iPB/h3xOcZxZw632	rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606	intact-crc:40F09653B7FF5882|rigid:cNhRrV6oEHcS5DGd4QpID2VF1Xc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46379	uniprotkb:Q8ZGX4	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2840069|uniprotkb:Q74W78|uniprotkb:Q0WHQ0|uniprotkb:Q7CH64	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:6pgl_yerpe(display_long)|uniprotkb:pgl(gene name)|psi-mi:pgl(display_short)|uniprotkb:YPO1149(locus name)|uniprotkb:y3033(locus name)|uniprotkb:YP_1011(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875071|imex:IM-13779-8229	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"refseq:YP_002346188.1|interpro:IPR022528|interpro:IPR019405|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0009051""(pentose-phosphate shunt, oxidative branch)|go:""GO:0017057""(6-phosphogluconolactonase activity)|refseq:WP_002210760.1|interpro:IPR050282|panther:PTHR30344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:noKVC/wB8Hf1xbPbMQHTszCjTss632	intact-crc:BF4FD47E3A184D80|rigid:RG8Ntf/fLRK3yRFpjlFIyjqQWYE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIV7	uniprotkb:Q99933	intact:EBI-2875111|uniprotkb:Q0WJT2	intact:EBI-1030678|uniprotkb:O75315|uniprotkb:Q14414|uniprotkb:Q96TG2|uniprotkb:Q9Y2V4|uniprotkb:Q53H32|uniprotkb:Q5VZE8|uniprotkb:Q5VZE9|uniprotkb:Q5VZF0|ensembl:ENSP00000489189.2	psi-mi:pura_yerpe(display_long)|uniprotkb:purA(gene name)|psi-mi:purA(display_short)|uniprotkb:IMP--aspartate ligase(gene name synonym)|uniprotkb:YPO0378(locus name)|uniprotkb:y0635(locus name)|uniprotkb:YP_0534(locus name)	psi-mi:bag1_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:Bcl-2-associated athanogene 1(gene name synonym)|uniprotkb:HAP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875116|imex:IM-13779-8233	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033128|interpro:IPR018220|interpro:IPR001114(Adenylosuccinate synthetase)|rcsb pdb:3HID|interpro:IPR027417|refseq:WP_002209157.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004019""(adenylosuccinate synthase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0044208""('de novo' AMP biosynthetic process)|go:""GO:0046040""(IMP metabolic process)|interpro:IPR042109|interpro:IPR042110|interpro:IPR042111|refseq:YP_002345456.1|panther:PTHR11846(orthology-group)"	"refseq:NP_001165886.1|refseq:NP_004314.5|dip:DIP-3341N|ensembl:ENSG00000107262.26(gene)|ensembl:ENST00000634734.3(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034393""(positive regulation of smooth muscle cell apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0050821""(protein stabilization)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0051087""(protein-folding chaperone binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR029071|interpro:IPR036533|interpro:IPR039773|mint:Q99933|rcsb pdb:1HX1|rcsb pdb:1WXV|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|reactome:R-HSA-3371453|panther:PTHR12329(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LmgdJ8ee/JI1tiTLvYcDKFw7x/A632	rogid:wDyAGECTy45td5tL4mnwa1txPO49606	intact-crc:46CA4814D20D654E|rigid:RTeCCyesZSc8yLV6OYVtXRqP07o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NDB2	uniprotkb:A0A3N4BB07	intact:EBI-2837677|uniprotkb:Q8NB56|uniprotkb:Q8WYN5|uniprotkb:A8K7W8|uniprotkb:B0F3S2|uniprotkb:Q8N5K8|uniprotkb:Q9NWP2|ensembl:ENSP00000320509.4	intact:EBI-2875102|uniprotkb:Q74R82|uniprotkb:A0A0H2W784|uniprotkb:Q7CKY8|uniprotkb:A0A384KSL0	psi-mi:bank1_human(display_long)|uniprotkb:BANK1(gene name)|psi-mi:BANK1(display_short)	psi-mi:a0a3n4bb07_yerpe(display_long)|uniprotkb:hemY(gene name)|psi-mi:hemY(display_short)|uniprotkb:YPO3852(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875099|imex:IM-13779-8235	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000153064.12(gene)|ensembl:ENST00000322953.9(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0002020""(protease binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0009617""(response to bacterium)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042113""(B cell activation)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050869""(negative regulation of B cell activation)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:1990782""(protein tyrosine kinase binding)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR017893|interpro:IPR035897|interpro:IPR036770|interpro:IPR041340|interpro:IPR052446|mint:Q8NDB2|refseq:NP_001077376.2|refseq:NP_001120979.2|refseq:NP_060405.4|refseq:XP_016863826.1|efo:""Orphanet:536""|panther:PTHR16267(orthology-group)"	"interpro:IPR010817(HemY, N-terminal)|interpro:IPR005254(Protoheme IX biosynthesis protein)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_002211462.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006779""(porphyrin-containing compound biosynthetic process)|go:""GO:0042168""(heme metabolic process)|refseq:YP_002348730.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gPC1vBSnrC6JMDRarNZgFBhuaEs9606	rogid:icCAww/2eTEfRzNXXhGw/XvwHWM632	intact-crc:2C9C487A02AC2CC4|rigid:aSDO0ycRpXKFnTz3/8gyWZrDBYs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA28	uniprotkb:Q92560	intact:EBI-2845659|uniprotkb:Q0WA26	intact:EBI-1791447|ensembl:ENSP00000417132.1|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090	psi-mi:dcta_yerpe(display_long)|uniprotkb:dctA(gene name)|psi-mi:dctA(display_short)|uniprotkb:YPO3992(locus name)|uniprotkb:y3836(locus name)|uniprotkb:YP_3355(locus name)	psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875092|imex:IM-13779-8232	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023954|interpro:IPR001991(""Sodium:dicarboxylate symporter"")|interpro:IPR018107|go:""GO:0005886""(plasma membrane)|go:""GO:0015138""(fumarate transmembrane transporter activity)|go:""GO:0015141""(succinate transmembrane transporter activity)|go:""GO:0015366""(""malate:proton symporter activity"")|go:""GO:0070778""(L-aspartate transmembrane transport)|refseq:WP_002209553.1|interpro:IPR036458|refseq:YP_002348862.1|panther:PTHR42865(orthology-group)"	"ensembl:ENSG00000163930.10(gene)|ensembl:ENST00000460680.6(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001894""(tissue homeostasis)|go:""GO:0002574""(thrombocyte differentiation)|go:""GO:0003682""(chromatin binding)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0008233""(peptidase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010467""(gene expression)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0030223""(neutrophil differentiation)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0033028""(myeloid cell apoptotic process)|go:""GO:0035517""(PR-DUB complex)|go:""GO:0035520""(monoubiquitinated protein deubiquitination)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0036211""(protein modification process)|go:""GO:0036344""(platelet morphogenesis)|go:""GO:0043249""(erythrocyte maturation)|go:""GO:0043363""(nucleate erythrocyte differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|go:""GO:0061519""(macrophage homeostasis)|go:""GO:0070050""(neuron cellular homeostasis)|go:""GO:0070661""(leukocyte proliferation)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:0140950""(histone H2A deubiquitinase activity)|go:""GO:1900015""(regulation of cytokine production involved in inflammatory response)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|rcsb pdb:7VPW|rcsb pdb:8H1T|rcsb pdb:8SVF|reactome:R-HSA-5689603|reactome:R-HSA-5693565|refseq:NP_004647.1|dip:DIP-47004N|efo:""Orphanet:2495""|efo:""Orphanet:289539""|efo:""Orphanet:39044""|efo:""Orphanet:50251""|efo:""Orphanet:528084""|efo:""Orphanet:618""|ensembl:ENSP00000417132.1|panther:PTHR10589(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:PB8pH1RlmRnUC4LznidUis7KghM632	rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606	intact-crc:2EAE8D869A8CC5E8|rigid:uL6pNX+GdNIYeFYIFMwVNmpMziU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P51572	uniprotkb:Q8ZIL4	intact:EBI-77683|uniprotkb:Q13836|uniprotkb:Q96CF0|uniprotkb:D3DWV5|uniprotkb:B3KQ79|ensembl:ENSP00000343458.6|ensembl:ENSP00000494052.1|ensembl:ENSP00000499882.1	intact:EBI-2852663|uniprotkb:Q0WJI3	psi-mi:bap31_human(display_long)|uniprotkb:BCAP31(gene name)|psi-mi:BCAP31(display_short)|uniprotkb:BAP31(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:6C6-AG tumor-associated antigen(gene name synonym)|uniprotkb:DXS1357E(gene name synonym)|uniprotkb:Protein CDM(gene name synonym)	psi-mi:carb_yerpe(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:YPO0482(locus name)|uniprotkb:YP_3697(locus name)|uniprotkb:y3692(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875085|imex:IM-13779-8236	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR12701(orthology-group)|efo:""Orphanet:369939""|efo:""Orphanet:369942""|ensembl:ENSG00000185825.17(gene)|ensembl:ENST00000345046.12(transcript)|ensembl:ENST00000647529.1(transcript)|ensembl:ENST00000672675.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006626""(protein targeting to mitochondrion)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016020""(membrane)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070973""(protein localization to endoplasmic reticulum exit site)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1904154""(positive regulation of retrograde protein transport, ER to cytosol)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:P51572|rcsb pdb:4JZL|rcsb pdb:4JZP|rcsb pdb:8XWX|reactome:R-HSA-111465|reactome:R-HSA-75153|reactome:R-HSA-8980692|reactome:R-HSA-983170|reactome:R-HSA-9833110|refseq:NP_001132913.1|refseq:NP_001132929.1|refseq:NP_001243376.1|refseq:NP_005736.3"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|refseq:WP_002210502.1|go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR033937|interpro:IPR036897|interpro:IPR036914|refseq:YP_002345555.1|panther:PTHR11405(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/06	rogid:m0aN00PLZJDWA/K1vEbla1W9+S89606	rogid:l/RzabCD1P/dEo/AmaYoXpYV1FY632	intact-crc:14BCCC8D86907852|rigid:2rvyD0e1vVzWZm1DfhKZTuRl8kA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PKW4	uniprotkb:O00154	intact:EBI-2849768|uniprotkb:Q74WE2|uniprotkb:A0A5P8YE16|uniprotkb:Q7CH90|uniprotkb:A0A0H2W1N2	intact:EBI-948905|uniprotkb:O43703|uniprotkb:Q53Y78|uniprotkb:Q5JYL2|uniprotkb:Q5JYL3|uniprotkb:Q5JYL4|uniprotkb:Q5JYL5|uniprotkb:Q5JYL6|uniprotkb:Q5TGR4|uniprotkb:Q9UJM9|uniprotkb:Q9Y539|uniprotkb:Q9Y540|uniprotkb:A8K0K7|uniprotkb:A8K232|uniprotkb:A8K6B8|uniprotkb:A8K837|uniprotkb:B3KQ12|ensembl:ENSP00000367086.2	psi-mi:a0a2s9pkw4_yerpe(display_long)|uniprotkb:dinG(gene name)|psi-mi:dinG(display_short)|uniprotkb:DNA 5'-3' helicase DinG(gene name synonym)|uniprotkb:rarB(gene name synonym)|uniprotkb:YPO1206(locus name)	psi-mi:bach_human(display_long)|uniprotkb:Long chain acyl-CoA thioester hydrolase(gene name synonym)|uniprotkb:Acyl-CoA thioesterase 7(gene name synonym)|uniprotkb:CTE-IIa(gene name synonym)|uniprotkb:Brain acyl-CoA hydrolase(gene name synonym)|uniprotkb:BACH(gene name synonym)|uniprotkb:ACOT7(gene name)|psi-mi:ACOT7(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875123|imex:IM-13779-8234	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR010614(DEAD2)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR027417|refseq:WP_002210810.1|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|go:""GO:0016818""(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:""GO:0016853""(isomerase activity)|go:""GO:0043139""(5'-3' DNA helicase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR039000|refseq:YP_002346240.1|interpro:IPR045028"	"refseq:NP_863655.1|refseq:NP_863656.1|refseq:NP_009205.3|refseq:NP_863654.1|ensembl:ENSG00000097021.21(gene)|ensembl:ENST00000377855.6(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006637""(acyl-CoA metabolic process)|go:""GO:0009062""(fatty acid catabolic process)|go:""GO:0015937""(coenzyme A biosynthetic process)|go:""GO:0036042""(long-chain fatty acyl-CoA binding)|go:""GO:0036114""(medium-chain fatty-acyl-CoA catabolic process)|go:""GO:0036116""(long-chain fatty-acyl-CoA catabolic process)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0051792""(medium-chain fatty acid biosynthetic process)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0052816""(long-chain fatty acyl-CoA hydrolase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1900535""(palmitic acid biosynthetic process)|interpro:IPR006683(Thioesterase superfamily)|interpro:IPR029069|interpro:IPR033120|interpro:IPR040170|mint:O00154|rcsb pdb:2QQ2|reactome:R-HSA-77289|panther:PTHR11049(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Pz/QYhpy8rsVBaUUTk559v1mAL4632	rogid:Tv8nHSqfXMmzZqj71+Gec6+29/s9606	intact-crc:C1813F7C894EE733|rigid:qcOfYpMNGQtmHxrGjULHxzmQTJ0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WKD7	uniprotkb:O60512	intact:EBI-2842097|uniprotkb:Q74Y17|uniprotkb:Q7CFV7|uniprotkb:A0A380PIN1|uniprotkb:A0A0H2W080	intact:EBI-714464|uniprotkb:D3DVG3|uniprotkb:O60910|uniprotkb:Q9BPZ4|uniprotkb:Q9H8T2|ensembl:ENSP00000320965.5|ensembl:ENSP00000356977.1|ensembl:ENSP00000480428.1	psi-mi:q0wkd7_yerpe(display_long)|uniprotkb:YPO0165(locus name)	"psi-mi:b4gt3_human(display_long)|uniprotkb:Neolactotriaosylceramide beta-1,4-galactosyltransferase(gene name synonym)|uniprotkb:""UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3""(gene name synonym)|uniprotkb:""UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3""(gene name synonym)|uniprotkb:B4GALT3(gene name)|psi-mi:B4GALT3(display_short)|uniprotkb:Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase(gene name synonym)|uniprotkb:Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase(gene name synonym)|uniprotkb:N-acetyllactosamine synthase(gene name synonym)|uniprotkb:Nal synthase(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875144|imex:IM-13779-8238	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000843(Bacterial regulatory protein, LacI)|interpro:IPR028082|go:""GO:0003677""(DNA binding)|go:""GO:0006355""(regulation of DNA-templated transcription)|refseq:WP_002208881.1|refseq:YP_002345251.1|interpro:IPR046335"	"refseq:NP_001186802.1|refseq:NP_001186803.1|refseq:NP_003770.1|refseq:XP_005245623.1|ensembl:ENSG00000158850.15(gene)|ensembl:ENST00000319769.10(transcript)|ensembl:ENST00000367998.5(transcript)|ensembl:ENST00000622395.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003831""(beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity)|go:""GO:0003945""(N-acetyllactosamine synthase activity)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006682""(galactosylceramide biosynthetic process)|go:""GO:0008378""(galactosyltransferase activity)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070085""(glycosylation)|interpro:IPR003859(Metazoa galactosyltransferase)|interpro:IPR027791|interpro:IPR027995|interpro:IPR029044|reactome:R-HSA-2022854|reactome:R-HSA-975577|panther:PTHR19300(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:djLG9eflkpuHq1g4QCFSjvuK4eI632	rogid:qX5WXfh0chDXNgC3zOmZcPXe8VE9606	intact-crc:66948560D289FF71|rigid:cSkGugLaE2egh3E3EjA2SpS+OfI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PGH0	uniprotkb:P04920	intact:EBI-2843672|uniprotkb:Q74VD9|uniprotkb:Q7CHN7|uniprotkb:A0A380SBG1|uniprotkb:Q0WGU1	intact:EBI-1390787|uniprotkb:Q45EY5|uniprotkb:Q969L3|uniprotkb:D3DX05|uniprotkb:B2R6T0|uniprotkb:B4DIT0|uniprotkb:F8W682|ensembl:ENSP00000405600.2|ensembl:ENSP00000419412.1	psi-mi:a0a2s9pgh0_yerpe(display_long)|uniprotkb:YPO1482(locus name)	psi-mi:b3a2_human(display_long)|uniprotkb:SLC4A2(gene name)|psi-mi:SLC4A2(display_short)|uniprotkb:AE2(gene name synonym)|uniprotkb:EPB3L1(gene name synonym)|uniprotkb:HKB3(gene name synonym)|uniprotkb:MPB3L(gene name synonym)|uniprotkb:Non-erythroid band 3-like protein(gene name synonym)|uniprotkb:Solute carrier family 4 member 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875151|imex:IM-13779-8239	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010623(Protein of unknown function DUF1215)|interpro:IPR009612(ImcF-related)|refseq:WP_002211936.1|interpro:IPR048677|refseq:YP_002346497.1|interpro:IPR053156	"refseq:NP_001186621.1|refseq:NP_001186623.1|refseq:NP_003031.3|refseq:NP_001186622.1|ensembl:ENSG00000164889.15(gene)|ensembl:ENST00000413384.7(transcript)|ensembl:ENST00000485713.5(transcript)|go:""GO:0005452""(""solute:inorganic anion antiporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006820""(monoatomic anion transport)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008509""(monoatomic anion transmembrane transporter activity)|go:""GO:0015701""(bicarbonate transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0043377""(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:""GO:0045124""(regulation of bone resorption)|go:""GO:0048565""(digestive tract development)|go:""GO:0051453""(regulation of intracellular pH)|go:""GO:0055085""(transmembrane transport)|go:""GO:0070175""(positive regulation of enamel mineralization)|go:""GO:0097186""(amelogenesis)|go:""GO:0140900""(""chloride:bicarbonate antiporter activity"")|go:""GO:2000565""(negative regulation of CD8-positive, alpha-beta T cell proliferation)|interpro:IPR001717(Anion exchange protein)|interpro:IPR002978(Anion exchange protein 2)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR018241|mint:P04920|rcsb pdb:8GV8|rcsb pdb:8GV9|rcsb pdb:8GVA|rcsb pdb:8GVC|rcsb pdb:8GVE|rcsb pdb:8GVF|rcsb pdb:8GVH|rcsb pdb:8JNI|rcsb pdb:8JNJ|rcsb pdb:8ZLE|reactome:R-HSA-425381|panther:PTHR11453(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QiN5WQU27+ZNFJoP65QaVCbJABo632	rogid:khJ5Stwond2oto/uqDNzRYDX48U9606	intact-crc:03777D4CCEF5BE4B|rigid:iAwAFZXXy+k+gFm9QujlbAKM9vM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q8Z9U2	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2843724|uniprotkb:Q0W9T4	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:mnme_yerpe(display_long)|uniprotkb:mnmE(gene name)|psi-mi:mnmE(display_short)|uniprotkb:thdF(gene name synonym)|uniprotkb:trmE(gene name synonym)|uniprotkb:YPO4103(locus name)|uniprotkb:y4118(locus name)|uniprotkb:YP_4010(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875158|imex:IM-13779-8241	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR018948|interpro:IPR004520(tRNA modification GTPase TrmE)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR025867|interpro:IPR027417|interpro:IPR031168|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0046872""(metal ion binding)|interpro:IPR027266|interpro:IPR027368|refseq:YP_002348954.1|panther:PTHR42714(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:XaI2j4tZS0U65rUmSnAsXuaqAKo632	intact-crc:1432D7B54BFA950D|rigid:xzRW4kGTJNAYEbMTCTMjRgxYycY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BYV9	uniprotkb:A0A0H2W225	intact:EBI-1642333|uniprotkb:E1P518|uniprotkb:Q59H70|uniprotkb:Q5T793|uniprotkb:Q9NTS5|ensembl:ENSP00000257749.4|ensembl:ENSP00000345642.3|ensembl:ENSP00000384145.3|ensembl:ENSP00000397668.2|ensembl:ENSP00000512284.1	intact:EBI-2844774	psi-mi:bach2_human(display_long)|uniprotkb:BACH2(gene name)|psi-mi:BACH2(display_short)|uniprotkb:BTB and CNC homolog 2(gene name synonym)	psi-mi:a0a0h2w225_yerpe(display_long)|uniprotkb:sbcC2(gene name)|psi-mi:sbcC2(display_short)|uniprotkb:sbcC(gene name synonym)|uniprotkb:YP_0725(locus name)|uniprotkb:y0976(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875130|imex:IM-13779-8237	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011534341.1|refseq:XP_011534342.1|refseq:NP_001164265.1|refseq:NP_068585.1|refseq:XP_005248816.1|refseq:XP_016866654.1|refseq:XP_016866655.1|ensembl:ENSG00000112182.16(gene)|ensembl:ENST00000257749.9(transcript)|ensembl:ENST00000343122.7(transcript)|ensembl:ENST00000406998.7(transcript)|ensembl:ENST00000453877.6(transcript)|ensembl:ENST00000695952.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0051170""(import into nucleus)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0090721""(primary adaptive immune response involving T cells and B cells)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR043321|interpro:IPR046347|interpro:IPR050457|rcsb pdb:3OHU|rcsb pdb:3OHV|panther:PTHR46105(orthology-group)"	"interpro:IPR027417|interpro:IPR038729|uniprotkb:A0A6B3T1W4(uniprot-removed-ac)|go:""GO:0004527""(exonuclease activity)|go:""GO:0006302""(double-strand break repair)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002223265.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yITQfsup6YNNo06tqFvTMqybh8w9606	rogid:kLIIS2zCAycudIvZsl7pSdsTqz0632	intact-crc:4EB99B2420EC65E9|rigid:IGEEgjz956Hp3b5D4dPHkbi977o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BEU0	uniprotkb:O60512	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	intact:EBI-714464|uniprotkb:D3DVG3|uniprotkb:O60910|uniprotkb:Q9BPZ4|uniprotkb:Q9H8T2|ensembl:ENSP00000320965.5|ensembl:ENSP00000356977.1|ensembl:ENSP00000480428.1	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	"psi-mi:b4gt3_human(display_long)|uniprotkb:Neolactotriaosylceramide beta-1,4-galactosyltransferase(gene name synonym)|uniprotkb:""UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3""(gene name synonym)|uniprotkb:""UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3""(gene name synonym)|uniprotkb:B4GALT3(gene name)|psi-mi:B4GALT3(display_short)|uniprotkb:Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase(gene name synonym)|uniprotkb:Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase(gene name synonym)|uniprotkb:N-acetyllactosamine synthase(gene name synonym)|uniprotkb:Nal synthase(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875137|imex:IM-13779-8240	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	"refseq:NP_001186802.1|refseq:NP_001186803.1|refseq:NP_003770.1|refseq:XP_005245623.1|ensembl:ENSG00000158850.15(gene)|ensembl:ENST00000319769.10(transcript)|ensembl:ENST00000367998.5(transcript)|ensembl:ENST00000622395.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003831""(beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity)|go:""GO:0003945""(N-acetyllactosamine synthase activity)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006682""(galactosylceramide biosynthetic process)|go:""GO:0008378""(galactosyltransferase activity)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070085""(glycosylation)|interpro:IPR003859(Metazoa galactosyltransferase)|interpro:IPR027791|interpro:IPR027995|interpro:IPR029044|reactome:R-HSA-2022854|reactome:R-HSA-975577|panther:PTHR19300(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	rogid:qX5WXfh0chDXNgC3zOmZcPXe8VE9606	intact-crc:A473A8DB8D56CD14|rigid:e8wgGpEIOA+ijqQ8tTWNs9wuPco	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q8D1J6	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2848106|uniprotkb:Q74R63	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:q8d1j6_yerpe(display_long)|uniprotkb:cof3(gene name)|psi-mi:cof3(display_short)|uniprotkb:YP_3219(locus name)|uniprotkb:y0401(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875165|imex:IM-13779-8244	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR000150(Cof protein)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0016791""(phosphatase activity)|interpro:IPR036412|interpro:IPR023214"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:x7t5HiadL8tDg8jpwvxHHgrzBZE632	intact-crc:997FAC0B4A8FD4F9|rigid:eq4Zd5Tapdt648RslzAkqoh9dBQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D192	uniprotkb:P61769	intact:EBI-2842738|uniprotkb:Q74XQ4	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	psi-mi:q8d192_yerpe(display_long)|uniprotkb:cirA2(gene name)|psi-mi:cirA2(display_short)|uniprotkb:YP_0347(locus name)|uniprotkb:y0850(locus name)	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875172|imex:IM-13779-8242	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|go:""GO:0009279""(cell outer membrane)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:RzjHHCxJ6rMwWCbWf+N47U3e7QQ632	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	intact-crc:41BCAC0B4BEE3C34|rigid:08UA7rhlG9usWLdWp0zNJCuSF1A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0R4	uniprotkb:P61769	intact:EBI-2861358|uniprotkb:Q74T93	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	psi-mi:q8d0r4_yerpe(display_long)|uniprotkb:ugpB3(gene name)|psi-mi:ugpB3(display_short)|uniprotkb:YP_2296(locus name)|uniprotkb:y1712(locus name)	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875186|imex:IM-13779-8245	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR050490|go:""GO:0016020""(membrane)|go:""GO:0030313""(cell envelope)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:WdQAdof8UnHcq+RBx3s9B0uCIlM632	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	intact-crc:F73ADD0B4A31025B|rigid:R7/w/OZZ9+U4x5K/9ms9WWKQC88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VBG2	uniprotkb:P61769	intact:EBI-2849663	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	psi-mi:a0a6b3vbg2_yerpe(display_long)|uniprotkb:yapB(gene name)|psi-mi:yapB(display_short)|uniprotkb:y1345(locus name)	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875179|imex:IM-13779-8243	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|uniprotkb:A0A6B3T6Y5(uniprot-removed-ac)|go:""GO:0019867""(outer membrane)|interpro:IPR051551"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:jNPx4rqCv9bEZelj7jbp42kW+NY632	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	intact-crc:98F72433E1B4E91F|rigid:epQwtELXjXMzK5iXqYNOPzZTuck	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q7CIZ3	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2852946|uniprotkb:Q74UE1	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:bgal_yerpe(display_long)|uniprotkb:lacZ(gene name)|psi-mi:lacZ(display_short)|uniprotkb:Lactase(gene name synonym)|uniprotkb:YPO1654(locus name)|uniprotkb:y1817(locus name)|uniprotkb:YP_1785(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875221|imex:IM-13779-8248	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR050347|interpro:IPR008979(Galactose-binding like)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR014718(Glycoside hydrolase-type carbohydrate-binding, subgroup)|interpro:IPR006101(Glycoside hydrolase, family 2)|interpro:IPR023232|interpro:IPR023933|interpro:IPR023230|interpro:IPR004199(Glycoside hydrolase, family 42, domain 5)|interpro:IPR006102(Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich)|interpro:IPR006104(Glycoside hydrolase family 2, carbohydrate-binding)|interpro:IPR006103(Glycoside hydrolase family 2, TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002214048.1|interpro:IPR032312|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004565""(beta-galactosidase activity)|go:""GO:0005990""(lactose catabolic process)|go:""GO:0009341""(beta-galactosidase complex)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036156|refseq:YP_002346664.1|panther:PTHR46323(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:RFOxfJbd+ZN/lJ/fIfkqbMSwF7w632	intact-crc:C3ADD2A594A50984|rigid:RzZ4X2Gk9LdH0Dkw0Va4JTDpeuQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:A0A0H2W1D0	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2850611|uniprotkb:Q74XN0|uniprotkb:Q0WBY0|uniprotkb:A0A3N4B5H8|uniprotkb:Q7CKA0|uniprotkb:A0A384KPX7	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:a0a0h2w1d0_yerpe(display_long)|uniprotkb:YPO3312(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875207|imex:IM-13779-8249	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR018485|interpro:IPR018484|interpro:IPR000577(Carbohydrate kinase, FGGY)|refseq:WP_002209440.1|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016301""(kinase activity)|interpro:IPR043129|interpro:IPR042016|refseq:YP_002348208.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:TkbiVPrlraU0BBleepm9BhezvWk632	intact-crc:2283F04437936DCE|rigid:Ql87XYBkpccTmY3tCEJGgOZC7yg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:A0A7Y8RCW6	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2845056|uniprotkb:Q7CKM5|uniprotkb:A0A5P8YBL8|uniprotkb:Q0WJU7	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:a0a7y8rcw6_yerpe(display_long)|uniprotkb:YPO0363(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875200|imex:IM-13779-8246	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR024393|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR011066(Mechanosensitive ion channel MscS, C-terminal)|interpro:IPR006685(Mechanosensitive ion channel MscS)|interpro:IPR011014(Mechanosensitive ion channel MscS, transmembrane-2)|interpro:IPR006686(Mechanosensitive ion channel MscS, conserved site)|interpro:IPR025692|go:""GO:0005886""(plasma membrane)|go:""GO:0008381""(mechanosensitive monoatomic ion channel activity)|interpro:IPR049142|interpro:IPR049278|interpro:IPR023408|refseq:YP_002345441.1|interpro:IPR052702"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:z6l0v0GxSQqbhV/esC/hffWqLG8632	intact-crc:2D6D38EC40D3A651|rigid:NRlT+kVLVJ48GQF6Lpy2+joVV8Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q7CIZ7	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2843304|uniprotkb:Q74UE8|uniprotkb:A0A384KZ59|uniprotkb:B4X9S5|uniprotkb:A0A0H2W3L1|uniprotkb:A0A5P8YGN2	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:q7ciz7_yerpe(display_long)|uniprotkb:appA(gene name)|psi-mi:appA(display_short)|uniprotkb:YPO1648(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875214|imex:IM-13779-8247	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR033379|interpro:IPR000560(Histidine acid phosphatase)|interpro:IPR029033|go:""GO:0003993""(acid phosphatase activity)|go:""GO:0008707""(4-phytase activity)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0050308""(sugar-phosphatase activity)|refseq:WP_002210903.1|refseq:YP_002346658.1|interpro:IPR050645|panther:PTHR11567(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:LJ8BlvMBlhdzSOKMptIEdIH68xQ632	intact-crc:77ADD2A595D6F461|rigid:oGclElxz09g8LuqoaWUBhr9JIgo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0H2	uniprotkb:P61769	intact:EBI-2852758|uniprotkb:Q74TR1	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	psi-mi:q8d0h2_yerpe(display_long)|uniprotkb:y2130(locus name)|uniprotkb:phoA(gene name)|psi-mi:phoA(display_short)|uniprotkb:YP_2083(locus name)	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875193|imex:IM-13779-8250	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001952(Alkaline phosphatase)|interpro:IPR018299|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|go:""GO:0016791""(phosphatase activity)|go:""GO:0046872""(metal ion binding)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:KhjfklmVQA9OcvPoJfuat/W+MmY632	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	intact-crc:2740DD0B4BFC90BE|rigid:gUMwSPrHA32b09Moryaoxhv3eOs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:A0A0H2W5A0	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2860643|uniprotkb:Q74TI3|uniprotkb:Q7CIS3|uniprotkb:A0A380SAX2|uniprotkb:Q0WED4	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:a0a0h2w5a0_yerpe(display_long)|uniprotkb:YPO2388(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875235|imex:IM-13779-8252	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|refseq:WP_002210942.1|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|refseq:YP_002347354.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:qusIJwX33yQEbGFFOo0bTmjGhto632	intact-crc:EB7222FE546C374A|rigid:JVuUmA+TAdj+jfWwBXWZpG4bw48	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:A0A2U2H346	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2849136|uniprotkb:Q74TG8|uniprotkb:A0A0H2W5H4|uniprotkb:Q0WEC0|uniprotkb:Q7CIT1|uniprotkb:A0A384KWM5	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:a0a2u2h346_yerpe(display_long)|uniprotkb:YPO2403(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875228|imex:IM-13779-8251	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR010231(SUF system FeS cluster assembly, SufB)|interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|refseq:WP_002211808.1|go:""GO:0016226""(iron-sulfur cluster assembly)|interpro:IPR037284|refseq:YP_002347368.1|interpro:IPR045595"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:DkCekEHB1T0D0zddmetEadbmVDk632	intact-crc:91AB8550562B078D|rigid:94BKA6kQh1TXkpIkQgI5KnmBhFw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GZ81	uniprotkb:P61769	intact:EBI-2844806|uniprotkb:Q0WF44|uniprotkb:Q7CIF0|uniprotkb:A0A5P8YG85|uniprotkb:A0A384LN40	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	psi-mi:a0a2u2gz81_yerpe(display_long)|uniprotkb:YPO2116(locus name)	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875242|imex:IM-13779-8254	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|interpro:IPR014918(Phage tail protein 3)|refseq:WP_002211713.1|refseq:YP_002347094.1	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:fLIU2ccxsfcp+e7nhqKs0Xnr90o632	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	intact-crc:1411986B6E7A7882|rigid:dO7w+n/vmqVxCM9j0BwL6mgg168	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:A0A2U2GYU0	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2847562|uniprotkb:A0A380PDR3|uniprotkb:Q0WFV2|uniprotkb:Q7CI00|uniprotkb:A0A384KNN0	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:a0a2u2gyu0_yerpe(display_long)|uniprotkb:flaF(gene name)|psi-mi:flaF(display_short)|uniprotkb:fliC(gene name synonym)|uniprotkb:hag(gene name synonym)|uniprotkb:YPO1842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875249|imex:IM-13779-8253	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR042187|refseq:WP_002211152.1|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009288""(bacterial-type flagellum)|refseq:YP_002346836.1|interpro:IPR046358"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:0iQC5KNYj/iy3Dwyc0YTHeiyqhs632	intact-crc:F000DB3E735B39B7|rigid:e9pzaX2GaRg74G2LcDFgvcBsY6w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:A0A2U2H442	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2850550|uniprotkb:Q74WH5|uniprotkb:A0A5P8YDV2|uniprotkb:Q0WHG4|uniprotkb:Q7CHB4|uniprotkb:A0A384LD81	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:a0a2u2h442_yerpe(display_long)|uniprotkb:YPO1245(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875270|imex:IM-13779-8256	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	refseq:WP_002208853.1|refseq:YP_002346274.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:BxXs1C2W2KnC7YYSP0bq8vjxXow632	intact-crc:66E329FAE601EC34|rigid:PUFqEhabFhYjOeFu7iMr534TxdQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q0WIJ7	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2851185|uniprotkb:Q74QE7|uniprotkb:A0A0H2W874|uniprotkb:A0A3N4B4F6|uniprotkb:Q7CGW9|uniprotkb:A0A384LBF7	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:q0wij7_yerpe(display_long)|uniprotkb:YPO0840(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875277|imex:IM-13779-8257	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010905(Glycosyl hydrolase, family 88)|refseq:WP_002209884.1|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR012341(Six-hairpin glycosidase)|refseq:YP_002345891.1|interpro:IPR052043"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:OJNnsHqKxXDsmBDCvDpKtYoti2k632	intact-crc:4F854263C2D33B92|rigid:+5Foou1/2do3tIwRm8Bz0tl/iYI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:A0A5P8YED3	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2854280|uniprotkb:Q0WHC6|uniprotkb:Q7CHD9|uniprotkb:A0A384L0S4	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:a0a5p8yed3_yerpe(display_long)|uniprotkb:YPO1286(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875263|imex:IM-13779-8258	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	interpro:IPR052572|interpro:IPR005358(Protein of unknown function UPF0153)|refseq:WP_002208811.1|refseq:YP_002346312.1|panther:PTHR36931(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:xi1BijFluPDXuPfEHIwAzy+vb5s632	intact-crc:3FF1317A940F2A9F|rigid:bKBAWqG7X82J1QvJpH1m/lDISsE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:A0A0H2W7E2	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2848155|uniprotkb:A0A2U2H0T1|uniprotkb:Q74QL8|uniprotkb:Q0WI49|uniprotkb:Q7CGN6|uniprotkb:A0A384KKB9	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:a0a0h2w7e2_yerpe(display_long)|uniprotkb:iutA(gene name)|psi-mi:iutA(display_short)|uniprotkb:YPO0994(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875284|imex:IM-13779-8259	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|refseq:WP_002211646.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002346039.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:h+zziPxtFmhqRng+3zCsRqmsI/M632	intact-crc:AD857792DA1DDABD|rigid:nkKBOVzBG4aOu6zIvPvz7LLHtXg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q0WG23	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2865571|uniprotkb:Q74US4|uniprotkb:A0A0H2W4X1|uniprotkb:Q7CHV8|uniprotkb:A0A384KQ92	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:q0wg23_yerpe(display_long)|uniprotkb:hpaX(gene name)|psi-mi:hpaX(display_short)|uniprotkb:YPO1768(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875256|imex:IM-13779-8255	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR012707(4-hydroxyphenylacetate permease)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|refseq:WP_002211076.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:1900754""(4-hydroxyphenylacetate transport)|go:""GO:1901241""(4-hydroxyphenylacetate transmembrane transporter activity)|interpro:IPR036259|refseq:YP_002346765.1|panther:PTHR43791(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:pkeFuahq4iOgbU/nZnL83wCcdE8632	intact-crc:6F79EC63C3B0D288|rigid:dOdaokDadz+BlrOXYZuyHbd2cYI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:A0A7Y8RC16	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2843188|uniprotkb:Q74PV7|uniprotkb:A0A0H2W7X5|uniprotkb:Q7CG44|uniprotkb:Q0WJQ7|uniprotkb:A0A384KPQ0	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:a0a7y8rc16_yerpe(display_long)|uniprotkb:YPO0404(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875291|imex:IM-13779-8262	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR006327(Phosphotransferase system, fructose IIC component)|interpro:IPR013014(Phosphotransferase system, EIIC component, type 2)|go:""GO:0005351""(""carbohydrate:proton symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|refseq:YP_002345481.1|interpro:IPR050864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:SLkzxzvdatLCfveYdH0UaKifvHU632	intact-crc:02F19D69CA1F1A6D|rigid:qjoNDAx4S9jZ/3JASVEfDqioRg0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZFB2	uniprotkb:P61769	intact:EBI-2842002|uniprotkb:Q0WFY8|uniprotkb:Q8CWH3|uniprotkb:Q74UV7	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	psi-mi:flgh2_yerpe(display_long)|uniprotkb:flgH2(gene name)|psi-mi:flgH2(display_short)|uniprotkb:Basal body L-ring protein 2(gene name synonym)|uniprotkb:YPO1805(locus name)|uniprotkb:y2504(locus name)|uniprotkb:YP_1588(locus name)	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875312|imex:IM-13779-8263	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000527(Flagellar L-ring protein)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009427""(bacterial-type flagellum basal body, distal rod, L ring)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:WP_002211116.1|refseq:YP_002346800.1|panther:PTHR34933(orthology-group)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:K+hG2Y1XkdBPEZly69izKbuTRvo632	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	intact-crc:BF0758B54BFEDD87|rigid:CLt8CkYy4N3dwbxy71C6v/ZQTZ8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5LJH8	uniprotkb:P61769	intact:EBI-2851477|uniprotkb:Q74YN1|uniprotkb:Q7ARE0|uniprotkb:Q7BT25|uniprotkb:A0A384KBQ0|uniprotkb:Q65AN4|uniprotkb:A0A1U8QEQ2|uniprotkb:A0A2U2H125|uniprotkb:O68752	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	psi-mi:a0a3g5ljh8_yerpe(display_long)|uniprotkb:YPMT1.34(locus name)	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875298|imex:IM-13779-8260	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395372.1|refseq:YP_093913.1|refseq:NP_857671.1|refseq:WP_002211799.1	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:EQfeZsF+Ifz/4ATGhKSB5pDt9HU632	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	intact-crc:7FD0CA5A64661143|rigid:SzjGnkX0h8uZztxbu8MhrD0XknQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q8ZAC2	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2840531|uniprotkb:Q0WAC4	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:ilvc_yerpe(display_long)|uniprotkb:ilvC(gene name)|psi-mi:ilvC(display_short)|uniprotkb:Acetohydroxy-acid isomeroreductase(gene name synonym)|uniprotkb:Alpha-keto-beta-hydroxylacyl reductoisomerase(gene name synonym)|uniprotkb:Ketol-acid reductoisomerase type 2(gene name synonym)|uniprotkb:Ketol-acid reductoisomerase type II(gene name synonym)|uniprotkb:YPO3888(locus name)|uniprotkb:YP_3158(locus name)|uniprotkb:y0345(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875305|imex:IM-13779-8261	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013023(Acetohydroxy acid isomeroreductase)|interpro:IPR000506(Acetohydroxy acid isomeroreductase C-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR013116(Acetohydroxy acid isomeroreductase, catalytic)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004455""(ketol-acid reductoisomerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|refseq:WP_002212007.1|refseq:YP_002348764.1|interpro:IPR036291|panther:PTHR21371(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:YXB9ATGj7Tcv7U9t7G60g2fFs+8632	intact-crc:60640FB54BFE80EE|rigid:0FWvp8Qy2Znr1EcNQgrsZ6DH9qY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W1D0	uniprotkb:O15169	intact:EBI-2850611|uniprotkb:Q74XN0|uniprotkb:Q0WBY0|uniprotkb:A0A3N4B5H8|uniprotkb:Q7CKA0|uniprotkb:A0A384KPX7	intact:EBI-710484|ensembl:ENSP00000262320.3|uniprotkb:Q4TT26|uniprotkb:Q4TT27|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	psi-mi:a0a0h2w1d0_yerpe(display_long)|uniprotkb:YPO3312(locus name)	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875340|imex:IM-13779-8265	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018485|interpro:IPR018484|interpro:IPR000577(Carbohydrate kinase, FGGY)|refseq:WP_002209440.1|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016301""(kinase activity)|interpro:IPR043129|interpro:IPR042016|refseq:YP_002348208.1"	"ensembl:ENSG00000103126.15(gene)|ensembl:ENST00000262320.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002039""(p53 binding)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009950""(dorsal/ventral axis specification)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030877""(beta-catenin destruction complex)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032147""(activation of protein kinase activity)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044725""(epigenetic programming in the zygotic pronuclei)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046332""(SMAD binding)|go:""GO:0048320""(axial mesoderm formation)|go:""GO:0048468""(cell development)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060322""(head development)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070411""(I-SMAD binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0071944""(cell periphery)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:1904885""(beta-catenin destruction complex assembly)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:1990909""(Wnt signalosome)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|interpro:IPR044926|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|rcsb pdb:7SXF|rcsb pdb:7SXG|rcsb pdb:7SXH|rcsb pdb:7SXJ|rcsb pdb:7Y1P|rcsb pdb:8RU3|rcsb pdb:8RU4|rcsb pdb:8VMG|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|refseq:NP_003493.1|refseq:NP_851393.1|efo:""Orphanet:210159""|dip:DIP-34630N|panther:PTHR46102(orthology-group)|ensembl:ENSP00000262320.3|ensembl:ENST00000354866.7|ensembl:ENSP00000346935.3"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:TkbiVPrlraU0BBleepm9BhezvWk632	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	intact-crc:615B828CB8AE1BB0|rigid:ve2/ITPbJgnPPstIU44aHclnW4Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKI9	uniprotkb:Q9BXK5	intact:EBI-2842458|uniprotkb:Q74QN4	intact:EBI-747430|uniprotkb:Q96B37|uniprotkb:Q96IB7|uniprotkb:Q9BY01|uniprotkb:Q9HC05|uniprotkb:Q9UFE0|uniprotkb:Q9UKN3|ensembl:ENSP00000318883.5|uniprotkb:B3KPE7	psi-mi:q8cki9_yerpe(display_long)|uniprotkb:proP29(gene name)|psi-mi:proP29(display_short)|uniprotkb:YP_3429(locus name)|uniprotkb:y3421(locus name)	psi-mi:b2l13_human(display_long)|uniprotkb:Protein Mil1(gene name synonym)|uniprotkb:Bcl-rambo(gene name synonym)|uniprotkb:BCL2L13(gene name)|psi-mi:BCL2L13(display_short)|uniprotkb:MIL1(gene name synonym)|uniprotkb:CD003(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875326|imex:IM-13779-8264	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011701(Major facilitator superfamily MFS-1)|go:""GO:0016020""(membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR004752(AmpG-related permease)|interpro:IPR036259"	"refseq:NP_056182.2|ensembl:ENSG00000099968.18(gene)|ensembl:ENST00000317582.10(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0061621""(canonical glycolysis)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR036834|interpro:IPR042398|interpro:IPR046371|mint:Q9BXK5|dip:DIP-60895N|refseq:NP_001257658.1|refseq:NP_001257659.1|refseq:NP_001257660.1|refseq:XP_011544423.1|refseq:XP_016884217.1|refseq:XP_016884218.1|refseq:XP_016884219.1|refseq:XP_016884220.1|refseq:XP_016884221.1|refseq:XP_016884222.1|panther:PTHR15758(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:LQJ7sCVje5CIoj8XDAEtssxYTPw632	rogid:CTVG9Xyunw/XyOeGX4zYaSXdo6Y9606	intact-crc:6F98D0CDB43F78E3|rigid:sLwsnuquW/rwlnbToIc5WFwognM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H6S1	uniprotkb:Q8ZCU2	intact:EBI-359973|intact:EBI-1384309|uniprotkb:Q86W99|uniprotkb:Q9BQF1|uniprotkb:A8K3M2|uniprotkb:C9JB40|uniprotkb:H7BXU6|ensembl:ENSP00000419371.1	intact:EBI-2861221|uniprotkb:Q0WD31	psi-mi:azi2_human(display_long)|uniprotkb:AZI2(gene name)|psi-mi:AZI2(display_short)|uniprotkb:NAP1(gene name synonym)|uniprotkb:TBKBP2(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase-associated protein 1(gene name synonym)|uniprotkb:TILP(gene name synonym)	psi-mi:ex7l_yerpe(display_long)|uniprotkb:xseA(gene name)|psi-mi:xseA(display_short)|uniprotkb:Exodeoxyribonuclease VII large subunit(gene name synonym)|uniprotkb:YPO2872(locus name)|uniprotkb:y1361(locus name)|uniprotkb:YP_2738(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875333|imex:IM-13779-8267	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001127904.1|refseq:NP_001127905.1|refseq:NP_071906.1|refseq:XP_005265449.1|ensembl:ENSG00000163512.14(gene)|ensembl:ENST00000479665.6(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0005737""(cytoplasm)|go:""GO:0042110""(T cell activation)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0044565""(dendritic cell proliferation)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0097028""(dendritic cell differentiation)|go:""GO:1902554""(serine/threonine protein kinase complex)|interpro:IPR024581|interpro:IPR051891|mint:Q9H6S1|rcsb pdb:5EP6|rcsb pdb:5Z7G|rcsb pdb:5Z7L|rcsb pdb:7EA2|rcsb pdb:7EA7|dip:DIP-27605N|panther:PTHR14432(orthology-group)"	"interpro:IPR020579|interpro:IPR003753(Exonuclease VII, large subunit)|interpro:IPR025824|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006308""(DNA catabolic process)|go:""GO:0008855""(exodeoxyribonuclease VII activity)|go:""GO:0009318""(exodeoxyribonuclease VII complex)|refseq:WP_002209810.1|refseq:YP_002347807.1|panther:PTHR30008(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lfjd4cD2rm6NOjdh3XTTuFxnK9A9606	rogid:zU89dTJy0spohd+cw3CGxfreDmk632	intact-crc:36A055CFEC935F1D|rigid:hHxAuHOzumnr2SM164ZK9Lw/H98	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15169	uniprotkb:A0A0H2W9A3	intact:EBI-710484|ensembl:ENSP00000262320.3|uniprotkb:Q4TT26|uniprotkb:Q4TT27|uniprotkb:Q86YA7|uniprotkb:Q8WVW6|uniprotkb:Q96S28	intact:EBI-2875347|uniprotkb:Q74PY1|uniprotkb:Q0WJN4|uniprotkb:Q7CG57|uniprotkb:A0A3N4BLD5|uniprotkb:A0A384KKB3	psi-mi:axin1_human(display_long)|uniprotkb:Axis inhibition protein 1(gene name synonym)|uniprotkb:AXIN1(gene name)|psi-mi:AXIN1(display_short)|uniprotkb:AXIN(gene name synonym)	psi-mi:a0a0h2w9a3_yerpe(display_long)|uniprotkb:holD(gene name synonym)|uniprotkb:b4372(gene name)|psi-mi:b4372(display_short)|uniprotkb:YPO0428(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875352|imex:IM-13779-8266	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000103126.15(gene)|ensembl:ENST00000262320.8(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002039""(p53 binding)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006915""(apoptotic process)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009950""(dorsal/ventral axis specification)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030877""(beta-catenin destruction complex)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032147""(activation of protein kinase activity)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044725""(epigenetic programming in the zygotic pronuclei)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046332""(SMAD binding)|go:""GO:0048320""(axial mesoderm formation)|go:""GO:0048468""(cell development)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060322""(head development)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070411""(I-SMAD binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0071944""(cell periphery)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0120283""(protein serine/threonine kinase binding)|go:""GO:1904885""(beta-catenin destruction complex assembly)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:1990909""(Wnt signalosome)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR032101|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|interpro:IPR044926|mint:O15169|rcsb pdb:1DK8|rcsb pdb:1EMU|rcsb pdb:1O9U|rcsb pdb:3ZDI|rcsb pdb:4B7T|rcsb pdb:4NM0|rcsb pdb:4NM3|rcsb pdb:4NM5|rcsb pdb:4NM7|rcsb pdb:4NU1|rcsb pdb:5WZZ|rcsb pdb:6JCK|rcsb pdb:7SXF|rcsb pdb:7SXG|rcsb pdb:7SXH|rcsb pdb:7SXJ|rcsb pdb:7Y1P|rcsb pdb:8RU3|rcsb pdb:8RU4|rcsb pdb:8VMG|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689880|reactome:R-HSA-8931987|reactome:R-HSA-8939256|reactome:R-HSA-9018519|refseq:NP_003493.1|refseq:NP_851393.1|efo:""Orphanet:210159""|dip:DIP-34630N|panther:PTHR46102(orthology-group)|ensembl:ENSP00000262320.3|ensembl:ENST00000354866.7|ensembl:ENSP00000346935.3"	"go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0006260""(DNA replication)|go:""GO:0008408""(3'-5' exonuclease activity)|interpro:IPR004615(DNA polymerase III, psi subunit)|refseq:WP_002209207.1|interpro:IPR036654|refseq:YP_002345504.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:uO+LxY/7ibIZqdd5onbfXqGAZeo9606	rogid:wyTwbUiKG9B5U/jDgkPz3xJBDOE632	intact-crc:85A03961C3B87618|rigid:OztZ6DE0fU17Usf2g8d+ShrmkGE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61769	uniprotkb:Q8ZIE7	intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191.1|ensembl:ENSP00000453350.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000497910.1	intact:EBI-2870020|uniprotkb:Q0WJB0	psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:ddl_yerpe(display_long)|uniprotkb:ddl(gene name)|psi-mi:ddl(display_short)|uniprotkb:ddlB(gene name synonym)|uniprotkb:D-Ala-D-Ala ligase(gene name synonym)|uniprotkb:D-alanylalanine synthetase(gene name synonym)|uniprotkb:YPO0557(locus name)|uniprotkb:y3624(locus name)|uniprotkb:YP_3627(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875319|imex:IM-13779-8268	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166710.23(gene)|ensembl:ENSG00000273686.4(gene)|ensembl:ENST00000559916.1(transcript)|ensembl:ENST00000561424.5(transcript)|ensembl:ENST00000617605.4(transcript)|ensembl:ENST00000631573.1(transcript)|ensembl:ENST00000631728.1(transcript)|ensembl:ENST00000648006.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002481""(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0007611""(learning or memory)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0031905""(early endosome lumen)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0071283""(""cellular response to iron(III) ion"")|go:""GO:0071316""(cellular response to nicotine)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|interpro:IPR050160|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3KYN|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3QZW|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3T8X|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4XXC|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5TXS|rcsb pdb:5U16|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB4|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7B5F|rcsb pdb:7BBG|rcsb pdb:7BH8|rcsb pdb:7C9V|rcsb pdb:7CIQ|rcsb pdb:7CIR|rcsb pdb:7CIS|rcsb pdb:7DUU|rcsb pdb:7DYN|rcsb pdb:7DZM|rcsb pdb:7DZN|rcsb pdb:7EDO|rcsb pdb:7EJL|rcsb pdb:7EJM|rcsb pdb:7EJN|rcsb pdb:7EU2|rcsb pdb:7F4W|rcsb pdb:7JWI|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7LLI|rcsb pdb:7LLJ|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MJ6|rcsb pdb:7MJ7|rcsb pdb:7MJ8|rcsb pdb:7MJ9|rcsb pdb:7MJA|rcsb pdb:7MKB|rcsb pdb:7MLE|rcsb pdb:7MX4|rcsb pdb:7MXF|rcsb pdb:7MXH|rcsb pdb:7N1A|rcsb pdb:7N1B|rcsb pdb:7N1E|rcsb pdb:7N1F|rcsb pdb:7N2N|rcsb pdb:7N2O|rcsb pdb:7N2P|rcsb pdb:7N2Q|rcsb pdb:7N2R|rcsb pdb:7N2S|rcsb pdb:7N4K|rcsb pdb:7N5C|rcsb pdb:7N5P|rcsb pdb:7N5Q|rcsb pdb:7N6D|rcsb pdb:7N6E|rcsb pdb:7N9J|rcsb pdb:7NA5|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7NMC|rcsb pdb:7NMD|rcsb pdb:7NME|rcsb pdb:7NMF|rcsb pdb:7NMG|rcsb pdb:7NMO|rcsb pdb:7NMR|rcsb pdb:7NMT|rcsb pdb:7NMV|rcsb pdb:7NMY|rcsb pdb:7NN5|rcsb pdb:7NUI|rcsb pdb:7OW3|rcsb pdb:7OW4|rcsb pdb:7OW5|rcsb pdb:7OW6|rcsb pdb:7P3D|rcsb pdb:7P3E|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:7PB2|rcsb pdb:7PBC|rcsb pdb:7PBE|rcsb pdb:7PDW|rcsb pdb:7PHR|rcsb pdb:7Q15|rcsb pdb:7Q98|rcsb pdb:7Q99|rcsb pdb:7Q9A|rcsb pdb:7Q9B|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7QPJ|rcsb pdb:7R7V|rcsb pdb:7R7W|rcsb pdb:7R7X|rcsb pdb:7R7Y|rcsb pdb:7R80|rcsb pdb:7RE7|rcsb pdb:7RE8|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7RTD|rcsb pdb:7RTR|rcsb pdb:7RYM|rcsb pdb:7RYN|rcsb pdb:7RYO|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:7S8Q|rcsb pdb:7S8R|rcsb pdb:7S8S|rcsb pdb:7SA2|rcsb pdb:7SH4|rcsb pdb:7SIF|rcsb pdb:7SIG|rcsb pdb:7SIH|rcsb pdb:7SIS|rcsb pdb:7STF|rcsb pdb:7SU9|rcsb pdb:7T0L|rcsb pdb:7T5M|rcsb pdb:7TLT|rcsb pdb:7TR4|rcsb pdb:7TUC|rcsb pdb:7TUD|rcsb pdb:7TUE|rcsb pdb:7U1R|rcsb pdb:7U21|rcsb pdb:7UC5|rcsb pdb:7UFJ|rcsb pdb:7UM2|rcsb pdb:7UMG|rcsb pdb:7UR1|rcsb pdb:7WJ2|rcsb pdb:7WJ3|rcsb pdb:7WKJ|rcsb pdb:7WT3|rcsb pdb:7WT4|rcsb pdb:7WT5|rcsb pdb:7WZZ|rcsb pdb:7X00|rcsb pdb:7X1B|rcsb pdb:7X1C|rcsb pdb:7XF3|rcsb pdb:7YG3|rcsb pdb:7ZT2|rcsb pdb:7ZT3|rcsb pdb:7ZT4|rcsb pdb:7ZT5|rcsb pdb:7ZT7|rcsb pdb:7ZT8|rcsb pdb:7ZT9|rcsb pdb:7ZUC|rcsb pdb:8A7O|rcsb pdb:8A7P|rcsb pdb:8A7Q|rcsb pdb:8A7T|rcsb pdb:8BP6|rcsb pdb:8CX4|rcsb pdb:8DNT|rcsb pdb:8DV3|rcsb pdb:8DV4|rcsb pdb:8DVG|rcsb pdb:8E13|rcsb pdb:8E2Z|rcsb pdb:8E8I|rcsb pdb:8EB2|rcsb pdb:8EC5|rcsb pdb:8EK5|rcsb pdb:8ELG|rcsb pdb:8ELH|rcsb pdb:8EMF|rcsb pdb:8EMG|rcsb pdb:8EMI|rcsb pdb:8EMJ|rcsb pdb:8EMK|rcsb pdb:8EN8|rcsb pdb:8ENH|rcsb pdb:8EO8|rcsb pdb:8ERX|rcsb pdb:8ES8|rcsb pdb:8ES9|rcsb pdb:8ESA|rcsb pdb:8ESH|rcsb pdb:8F5A|rcsb pdb:8F7M|rcsb pdb:8FJA|rcsb pdb:8FJB|rcsb pdb:8FRT|rcsb pdb:8FU4|rcsb pdb:8GLE|rcsb pdb:8GLF|rcsb pdb:8GLG|rcsb pdb:8GLH|rcsb pdb:8GLI|rcsb pdb:8GOM|rcsb pdb:8GON|rcsb pdb:8GVB|rcsb pdb:8GVG|rcsb pdb:8GVI|rcsb pdb:8HN4|rcsb pdb:8I5C|rcsb pdb:8I5D|rcsb pdb:8I5E|rcsb pdb:8ISN|rcsb pdb:8QFY|rcsb pdb:8RBU|rcsb pdb:8RBV|rcsb pdb:8RCV|rcsb pdb:8REF|rcsb pdb:8RH6|rcsb pdb:8RHQ|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|rcsb pdb:8RNG|rcsb pdb:8RNH|rcsb pdb:8ROO|rcsb pdb:8ROP|rcsb pdb:8RYM|rcsb pdb:8RYN|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8RYQ|rcsb pdb:8SBK|rcsb pdb:8SBL|rcsb pdb:8SGB|rcsb pdb:8SGM|rcsb pdb:8SHI|rcsb pdb:8SOS|rcsb pdb:8TBV|rcsb pdb:8TBW|rcsb pdb:8TNJ|rcsb pdb:8TUB|rcsb pdb:8TUH|rcsb pdb:8U9G|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|rcsb pdb:8VRB|rcsb pdb:8WTE|rcsb pdb:8WUL|rcsb pdb:8XES|rcsb pdb:8XFZ|rcsb pdb:8XG2|rcsb pdb:8XKC|rcsb pdb:8XKE|rcsb pdb:8YE4|rcsb pdb:8ZV9|rcsb pdb:9C3E|rcsb pdb:9C6V|rcsb pdb:9C6W|rcsb pdb:9C6X|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-9705671|reactome:R-HSA-977225|reactome:R-HSA-983170|refseq:NP_004039.1|dip:DIP-6055N|efo:""Orphanet:314652""|efo:""Orphanet:34592""|panther:PTHR19944(orthology-group)|ensembl:ENSP00000453191.1|ensembl:ENSP00000481426.1|ensembl:ENSP00000488548.1|ensembl:ENSP00000488321.1|ensembl:ENSP00000497910.1|ensembl:ENSP00000453350.1"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR000291(D-alanine--D-alanine ligase/VANA/B/C, conserved site)|interpro:IPR005905(D-alanine--D-alanine ligase)|interpro:IPR011095(D-alanine--D-alanine ligase, C-terminal)|interpro:IPR011127(D-alanine--D-alanine ligase, N-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:5BPF|rcsb pdb:5BPH|rcsb pdb:5C1O|rcsb pdb:5C1P|rcsb pdb:3V4Z|refseq:WP_002210432.1|rcsb pdb:4ZQI|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008716""(D-alanine-D-alanine ligase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0071555""(cell wall organization)|refseq:YP_002345628.1|panther:PTHR23132(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606	rogid:NMpRC51zhBG97/cvKC75+fOPDQY632	intact-crc:1CA987B54AD04A96|rigid:KvTokbScOXLmb+eZIR8Iq1OvGBY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WWM7	uniprotkb:A0A2U2GWL4	intact:EBI-948363|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4|ensembl:ENSP00000338718.4	intact:EBI-2842513|uniprotkb:Q74QF2|uniprotkb:Q0WIK2|uniprotkb:Q7CGX2|uniprotkb:A0A384KBZ2	psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym)	psi-mi:a0a2u2gwl4_yerpe(display_long)|uniprotkb:YPO0835(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875392|imex:IM-13779-8271	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1|ensembl:ENSG00000168488.19(gene)|ensembl:ENST00000336783.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0034063""(stress granule assembly)|go:""GO:0045296""(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|interpro:IPR045117|interpro:IPR047575|mint:Q8WWM7|panther:PTHR12854(orthology-group)"	"interpro:IPR004700(Phosphotransferase system, sorbose-specific IIC subunit)|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|refseq:WP_002209879.1|interpro:IPR047835|refseq:YP_002345886.1|interpro:IPR050303|panther:PTHR32502(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606	rogid:sFFGuU7nv2zkwyFSwvZPy1xxJLc632	intact-crc:6C5C542552BE3A0B|rigid:uGtsa+cbsA8r6X1n5iuQrTbiTEc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLN2	uniprotkb:Q8WXX7	intact:EBI-2855914|uniprotkb:Q74XS3	intact:EBI-2875359|ensembl:ENSP00000344087.4|uniprotkb:Q5D049|uniprotkb:Q9Y4F2|uniprotkb:A4D1Y9|uniprotkb:Q6PJU5|uniprotkb:L7QET3|uniprotkb:L7QF75	psi-mi:q8cln2_yerpe(display_long)|uniprotkb:YP_0317(locus name)|uniprotkb:y0821(locus name)	psi-mi:auts2_human(display_long)|uniprotkb:AUTS2(gene name)|psi-mi:AUTS2(display_short)|uniprotkb:KIAA0442(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875367|imex:IM-13779-8269	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR031807|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0043565""(sequence-specific DNA binding)|interpro:IPR035069"	"ensembl:ENSG00000158321.19(gene)|ensembl:ENST00000342771.10(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030426""(growth cone)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048675""(axon extension)|go:""GO:0097484""(dendrite extension)|interpro:IPR023246|mint:Q8WXX7|reactome:R-HSA-8939243|refseq:NP_001120703.1|refseq:NP_001120704.1|refseq:NP_056385.1|dip:DIP-61355N|efo:""Orphanet:352490""|efo:""Orphanet:641372""|panther:PTHR14429(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:MONUjv+Yr9ahHdYDsvGIFFjMTjw632	rogid:8m3VWlXEISEyVwNmlwDFEEKl4Sg9606	intact-crc:5AE83B5D4DBE1044|rigid:waMYwnEDxWUuBIdO67lJOC2mUz0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WWM7	uniprotkb:A0A2U2GUX9	intact:EBI-948363|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4|ensembl:ENSP00000338718.4	intact:EBI-2841416|uniprotkb:A0A0H2W940|uniprotkb:Q74PB0|uniprotkb:A0A384LLI5|uniprotkb:Q7CFN3|uniprotkb:A0A3N4BJ32	psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym)	psi-mi:a0a2u2gux9_yerpe(display_long)|uniprotkb:YPO4108(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875399|imex:IM-13779-8273	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1|ensembl:ENSG00000168488.19(gene)|ensembl:ENST00000336783.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0034063""(stress granule assembly)|go:""GO:0045296""(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|interpro:IPR045117|interpro:IPR047575|mint:Q8WWM7|panther:PTHR12854(orthology-group)"	"interpro:IPR023214|interpro:IPR041492|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002215575.1|refseq:YP_002348959.1|interpro:IPR023198|interpro:IPR036412|interpro:IPR051600"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606	rogid:N4DmZVhdbeJX1EvnC462dwFiaNU632	intact-crc:9E16F77F7CAA0325|rigid:7RKKoo8My3MDf2+5Eae+5XhDxJM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WWM7	uniprotkb:A0A380SAM5	intact:EBI-948363|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4|ensembl:ENSP00000338718.4	intact:EBI-2875381|uniprotkb:Q0WE22|uniprotkb:Q7CJ60	psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym)	psi-mi:a0a380sam5_yerpe(display_long)|uniprotkb:gutB(gene name)|psi-mi:gutB(display_short)|uniprotkb:YPO2502(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875385|imex:IM-13779-8270	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1|ensembl:ENSG00000168488.19(gene)|ensembl:ENST00000336783.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0034063""(stress granule assembly)|go:""GO:0045296""(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|interpro:IPR045117|interpro:IPR047575|mint:Q8WWM7|panther:PTHR12854(orthology-group)"	"go:""GO:0003939""(""L-iditol 2-dehydrogenase (NAD+) activity"")|go:""GO:0016020""(membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR011032(GroES-like)|interpro:IPR020843|interpro:IPR036291|refseq:YP_002347466.1|interpro:IPR050129|panther:PTHR43161(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606	rogid:mK9gD76AqWJJReOdme5qS3QQeDE632	intact-crc:749D91C2DF466AF2|rigid:UDEJ0s+Oqy0lkVOHXEqwrvaI4xI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1R0	uniprotkb:Q8WWM7	intact:EBI-2843803	intact:EBI-948363|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4|ensembl:ENSP00000338718.4	psi-mi:q8d1r0_yerpe(display_long)|uniprotkb:degQ(gene name)|psi-mi:degQ(display_short)|uniprotkb:y0137(locus name)	psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875374|imex:IM-13779-8272	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|interpro:IPR036034"	"refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1|ensembl:ENSG00000168488.19(gene)|ensembl:ENST00000336783.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0034063""(stress granule assembly)|go:""GO:0045296""(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|interpro:IPR045117|interpro:IPR047575|mint:Q8WWM7|panther:PTHR12854(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AA9pxma2K+wssT66h3sgiRuf6Uc632	rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606	intact-crc:24EC44BBC7074886|rigid:lul9ixw0+ikxnYaR+Pwzj3RsEtM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WWM7	uniprotkb:Q9ZC68	intact:EBI-948363|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4|ensembl:ENSP00000338718.4	intact:EBI-2843867|uniprotkb:Q7CI72|uniprotkb:Q74UK4	psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym)	psi-mi:astd_yerpe(display_long)|uniprotkb:astD(gene name)|psi-mi:astD(display_short)|uniprotkb:Succinylglutamic semialdehyde dehydrogenase(gene name synonym)|uniprotkb:YPO1964(locus name)|uniprotkb:y2347(locus name)|uniprotkb:YP_1709(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875413|imex:IM-13779-8274	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1|ensembl:ENSG00000168488.19(gene)|ensembl:ENST00000336783.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0034063""(stress granule assembly)|go:""GO:0045296""(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|interpro:IPR045117|interpro:IPR047575|mint:Q8WWM7|panther:PTHR12854(orthology-group)"	"refseq:WP_002212030.1|interpro:IPR029510|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR017649(Succinylglutamic semialdehyde dehydrogenase)|go:""GO:0019544""(arginine catabolic process to glutamate)|go:""GO:0019545""(arginine catabolic process to succinate)|go:""GO:0043824""(succinylglutamate-semialdehyde dehydrogenase activity)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:YP_002346953.1|panther:PTHR11699(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606	rogid:lAw8pbIH2i1IjXZl8H7zAJvQj0I632	intact-crc:2F4CD5D8B4F6ED21|rigid:2fX+g8qUrPRWBcV8PQsGat1LGCE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UHI8	uniprotkb:A0A5P8YFD8	intact:EBI-2511802|ensembl:ENSP00000284984.2|uniprotkb:Q9NSJ8|uniprotkb:Q9UP80|uniprotkb:Q9UH83|uniprotkb:Q9P2K0|uniprotkb:D3DSD5	intact:EBI-2844797|uniprotkb:Q74TW8|uniprotkb:A0A0H2W658|uniprotkb:Q7CIM3|uniprotkb:A0A384L807	psi-mi:ats1_human(display_long)|uniprotkb:ADAMTS1(gene name)|psi-mi:ADAMTS1(display_short)|uniprotkb:KIAA1346(gene name synonym)|uniprotkb:METH1(gene name synonym)|uniprotkb:METH-1(gene name synonym)	psi-mi:a0a5p8yfd8_yerpe(display_long)|uniprotkb:trpE(gene name)|psi-mi:trpE(display_short)|uniprotkb:YPO2208(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875427|imex:IM-13779-8275	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000154734.16(gene)|ensembl:ENST00000284984.8(transcript)|go:""GO:0001542""(ovulation from ovarian follicle)|go:""GO:0001822""(kidney development)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008201""(heparin binding)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0060347""(heart trabecula formation)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904754""(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR013273(Peptidase M12B, ADAM-TS)|interpro:IPR013274(Peptidase M12B, ADAM-TS1)|interpro:IPR024079|interpro:IPR036383|interpro:IPR041645|interpro:IPR045371|interpro:IPR050439|mint:Q9UHI8|rcsb pdb:2JIH|rcsb pdb:2V4B|rcsb pdb:3Q2G|rcsb pdb:3Q2H|reactome:R-HSA-1474228|reactome:R-HSA-5083635|reactome:R-HSA-5173214|refseq:NP_008919.3|panther:PTHR13723(orthology-group)"	"interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR019999|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR005257(Anthranilate synthase component I, TrpE)|interpro:IPR015890(Chorismate binding, C-terminal)|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004049""(anthranilate synthase activity)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347179.1|panther:PTHR11236(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/2rwfNnTU6Seo5+ZZdGeEEUeoAQ9606	rogid:4yY3KOTpkixAVvXxxbToZJUfRYM632	intact-crc:9801B7311E2D5DA6|rigid:3cJevftkHJ/+MJXy11uhqBwYqAM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75882	uniprotkb:Q0WGQ5	intact:EBI-2115457|uniprotkb:O60295|uniprotkb:O95414|uniprotkb:Q3MIT3|uniprotkb:Q5TDA2|uniprotkb:Q5TDA4|uniprotkb:Q5VYW3|uniprotkb:Q9NTQ3|uniprotkb:Q9NTQ4|uniprotkb:Q9NU01|uniprotkb:Q9NZ57|uniprotkb:Q9NZ58|uniprotkb:Q9UDF5|uniprotkb:A8KAE5|uniprotkb:Q9UC75|ensembl:ENSP00000262919.5	intact:EBI-2853517|uniprotkb:Q74VA6|uniprotkb:Q7CHR0	psi-mi:atrn_human(display_long)|uniprotkb:ATRN(gene name)|psi-mi:ATRN(display_short)|uniprotkb:KIAA0548(gene name synonym)|uniprotkb:MGCA(gene name synonym)|uniprotkb:Mahogany homolog(gene name synonym)|uniprotkb:DPPT-L(gene name synonym)	psi-mi:q0wgq5_yerpe(display_long)|uniprotkb:YPO1517(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875434|imex:IM-13779-8276	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193976.1|refseq:NP_647537.1|refseq:NP_647538.1|panther:PTHR46376(orthology-group)|refseq:NP_001310261.1|ensembl:ENSG00000088812.18(gene)|ensembl:ENST00000262919.10(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0021549""(cerebellum development)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042552""(myelination)|go:""GO:0043473""(pigmentation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001304(C-type lectin)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR016201(Plexin-like fold)|interpro:IPR034011|interpro:IPR035914|interpro:IPR051568|mint:O75882"	"interpro:IPR050555|interpro:IPR025997|interpro:IPR028082|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002346533.1|panther:PTHR30036(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+ccHme0r0hbuctGprE+6uUpj/1Q9606	rogid:qnuiW6B7FZ3gckfa7i2/HzKZAI8632	intact-crc:38EC72721043A743|rigid:42egMXlFh17P6GafFVeyNjEUlk0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZFX5	uniprotkb:Q8WWM7	intact:EBI-2851740|uniprotkb:Q0WGM4	intact:EBI-948363|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4|ensembl:ENSP00000338718.4	psi-mi:hisx_yerpe(display_long)|uniprotkb:hisD(gene name)|psi-mi:hisD(display_short)|uniprotkb:YPO1548(locus name)|uniprotkb:y2621(locus name)|uniprotkb:YP_1437(locus name)	psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875406|imex:IM-13779-8278	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR001692(Histidinol dehydrogenase)|interpro:IPR022695|interpro:IPR012131(Histidinol dehydrogenase, prokaryotic)|refseq:WP_002211895.1|go:""GO:0000105""(L-histidine biosynthetic process)|go:""GO:0004399""(histidinol dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0051287""(NAD binding)|refseq:YP_002346564.1|panther:PTHR21256(orthology-group)"	"refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1|ensembl:ENSG00000168488.19(gene)|ensembl:ENST00000336783.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0034063""(stress granule assembly)|go:""GO:0045296""(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|interpro:IPR045117|interpro:IPR047575|mint:Q8WWM7|panther:PTHR12854(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aXT+/ioqFLvYG1ayljhfqLE1ikU632	rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606	intact-crc:D976B005C62A077F|rigid:ssbGyND/mMK9B3PJrrsOs+NCb+M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1J6	uniprotkb:Q99700	intact:EBI-2848106|uniprotkb:Q74R63	intact:EBI-697691|uniprotkb:Q6ZQZ7|uniprotkb:Q99493|uniprotkb:A6NLD4|ensembl:ENSP00000446576.2|uniprotkb:Q24JQ7	psi-mi:q8d1j6_yerpe(display_long)|uniprotkb:cof3(gene name)|psi-mi:cof3(display_short)|uniprotkb:YP_3219(locus name)|uniprotkb:y0401(locus name)	psi-mi:atx2_human(display_long)|uniprotkb:Spinocerebellar ataxia type 2 protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 13 protein(gene name synonym)|uniprotkb:SCA2(gene name synonym)|uniprotkb:TNRC13(gene name synonym)|uniprotkb:ATXN2(gene name)|psi-mi:ATXN2(display_short)|uniprotkb:ATX2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875420|imex:IM-13779-8277	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR000150(Cof protein)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0016791""(phosphatase activity)|interpro:IPR036412|interpro:IPR023214"	"ensembl:ENSG00000204842.18(gene)|ensembl:ENST00000550104.5(transcript)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006417""(regulation of translation)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016070""(RNA metabolic process)|go:""GO:0033962""(P-body assembly)|go:""GO:0034063""(stress granule assembly)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050658""(RNA transport)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR025852|interpro:IPR045117|interpro:IPR047575|mint:Q99700|rcsb pdb:3KTR|refseq:NP_001297052.1|refseq:NP_002964.3|efo:""Orphanet:803""|efo:""Orphanet:98756""|dip:DIP-33372N|panther:PTHR12854(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:x7t5HiadL8tDg8jpwvxHHgrzBZE632	rogid:HGRv/9J/X3JIj2KmcHviwd2ygPw9606	intact-crc:6B76744D67110056|rigid:O/ig8LW81M3yBtTPccT3oQx/9qQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P54259	uniprotkb:A0A3G5L195	intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076.3|ensembl:ENSP00000379915.2	intact:EBI-2846239	psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym)	psi-mi:a0a3g5l195_yerpe(display_long)|uniprotkb:gltD_2(gene name synonym)|uniprotkb:NCTC5923_03556(orf name)|uniprotkb:YP_0496(locus name)|uniprotkb:y0599(locus name)|uniprotkb:gltD1(gene name)|psi-mi:gltD1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875448|imex:IM-13779-8282	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111676.15(gene)|ensembl:ENST00000356654.8(transcript)|ensembl:ENST00000396684.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001906""(cell killing)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008584""(male gonad development)|go:""GO:0009791""(post-embryonic development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0032094""(response to food)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0070161""(anchoring junction)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724|refseq:NP_001007027.1|refseq:NP_001931.2|dip:DIP-29423N|efo:""Orphanet:101""|panther:PTHR13859(orthology-group)"	"go:""GO:0016491""(oxidoreductase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|uniprotkb:A0A0H2W2I9(uniprot-removed-ac)|interpro:IPR006006(Glutamate synthase, NADH/NADPH, small subunit 2)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR017896|interpro:IPR017900|interpro:IPR023753|interpro:IPR028261|interpro:IPR036188|refseq:WP_002209118.1"	"psi-mi:""MI:0469""(intact)"	crc64:B47603486C672637	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606	rogid:O695WmNy+GxlzKIxVsZgUG5sXkQ632	intact-crc:0FD00FA42C99EA9F|rigid:IhgwK48hkfaK0N84j7QYogUyggI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA76	uniprotkb:P54259	intact:EBI-2846943|uniprotkb:Q0WA76	intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076.3|ensembl:ENSP00000379915.2	psi-mi:glgx_yerpe(display_long)|uniprotkb:glgX(gene name)|psi-mi:glgX(display_short)|uniprotkb:Limit dextrin alpha-1,6-maltotetraose-hydrolase(gene name synonym)|uniprotkb:YPO3941(locus name)|uniprotkb:YP_3303(locus name)|uniprotkb:y3887(locus name)	psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875469|imex:IM-13779-8283	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR022844|interpro:IPR011837(Glycogen debranching enzyme GlgX)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR040784|go:""GO:0004133""(obsolete glycogen debranching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005980""(glycogen catabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_002209499.1|interpro:IPR044505|refseq:YP_002348812.1|panther:PTHR43002(orthology-group)"	"ensembl:ENSG00000111676.15(gene)|ensembl:ENST00000356654.8(transcript)|ensembl:ENST00000396684.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001906""(cell killing)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008584""(male gonad development)|go:""GO:0009791""(post-embryonic development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0032094""(response to food)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0070161""(anchoring junction)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724|refseq:NP_001007027.1|refseq:NP_001931.2|dip:DIP-29423N|efo:""Orphanet:101""|panther:PTHR13859(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	crc64:B47603486C672637	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:8sHtj0obGqvrIdGE1JWk8okcbRM632	rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606	intact-crc:7538C3D6727D66F2|rigid:yRPhh76GtXSvqceV7SpWjkYym7w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P54259	uniprotkb:A0A0H2W206	intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076.3|ensembl:ENSP00000379915.2	intact:EBI-2850412|uniprotkb:Q74WX4|uniprotkb:Q0WC54|uniprotkb:A0A3N4AY03|uniprotkb:Q7CK63|uniprotkb:A0A384LHY7	psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym)	psi-mi:a0a0h2w206_yerpe(display_long)|uniprotkb:YPO3232(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875455|imex:IM-13779-8280	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111676.15(gene)|ensembl:ENST00000356654.8(transcript)|ensembl:ENST00000396684.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001906""(cell killing)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008584""(male gonad development)|go:""GO:0009791""(post-embryonic development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0032094""(response to food)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0070161""(anchoring junction)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724|refseq:NP_001007027.1|refseq:NP_001931.2|dip:DIP-29423N|efo:""Orphanet:101""|panther:PTHR13859(orthology-group)"	"interpro:IPR017946|refseq:WP_002208709.1|interpro:IPR030395|go:""GO:0006629""(lipid metabolic process)|go:""GO:0008081""(phosphoric diester hydrolase activity)|refseq:YP_002348134.1"	"psi-mi:""MI:0469""(intact)"	crc64:B47603486C672637	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606	rogid:w9E1M7ll1/8M9c7G+MFNmcATVX4632	intact-crc:5F89935E182AE8E5|rigid:4CnRzvCKmifU9nbyMQjfUpiYLVg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YKP4	uniprotkb:O75882	intact:EBI-2853948|uniprotkb:Q74RP4|uniprotkb:Q7CGH3|uniprotkb:Q0WJ06	intact:EBI-2115457|uniprotkb:O60295|uniprotkb:O95414|uniprotkb:Q3MIT3|uniprotkb:Q5TDA2|uniprotkb:Q5TDA4|uniprotkb:Q5VYW3|uniprotkb:Q9NTQ3|uniprotkb:Q9NTQ4|uniprotkb:Q9NU01|uniprotkb:Q9NZ57|uniprotkb:Q9NZ58|uniprotkb:Q9UDF5|uniprotkb:A8KAE5|uniprotkb:Q9UC75|ensembl:ENSP00000262919.5	psi-mi:a0a5p8ykp4_yerpe(display_long)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:YPO0664(locus name)	psi-mi:atrn_human(display_long)|uniprotkb:ATRN(gene name)|psi-mi:ATRN(display_short)|uniprotkb:KIAA0548(gene name synonym)|uniprotkb:MGCA(gene name synonym)|uniprotkb:Mahogany homolog(gene name synonym)|uniprotkb:DPPT-L(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875441|imex:IM-13779-8279	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020084|interpro:IPR004385(Nucleoside diphosphate pyrophosphatase)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:WP_002212184.1|go:""GO:0005829""(cytosol)|go:""GO:0006753""(nucleoside phosphate metabolic process)|go:""GO:0019144""(ADP-sugar diphosphatase activity)|go:""GO:0019693""(ribose phosphate metabolic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_002345732.1|panther:PTHR11839(orthology-group)"	"refseq:NP_001193976.1|refseq:NP_647537.1|refseq:NP_647538.1|panther:PTHR46376(orthology-group)|refseq:NP_001310261.1|ensembl:ENSG00000088812.18(gene)|ensembl:ENST00000262919.10(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0021549""(cerebellum development)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042552""(myelination)|go:""GO:0043473""(pigmentation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001304(C-type lectin)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR016201(Plexin-like fold)|interpro:IPR034011|interpro:IPR035914|interpro:IPR051568|mint:O75882"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ji/dszpJhw/6y6lx3coWs2NZfpY632	rogid:+ccHme0r0hbuctGprE+6uUpj/1Q9606	intact-crc:57E056B441C4351D|rigid:9yfQUIbTQtqvzDA2eH0PXNCLzk0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P54259	uniprotkb:A0A3N4BEU0	intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076.3|ensembl:ENSP00000379915.2	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym)	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875462|imex:IM-13779-8281	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111676.15(gene)|ensembl:ENST00000356654.8(transcript)|ensembl:ENST00000396684.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001906""(cell killing)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008584""(male gonad development)|go:""GO:0009791""(post-embryonic development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0032094""(response to food)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0070161""(anchoring junction)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724|refseq:NP_001007027.1|refseq:NP_001931.2|dip:DIP-29423N|efo:""Orphanet:101""|panther:PTHR13859(orthology-group)"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	"psi-mi:""MI:0469""(intact)"	crc64:B47603486C672637	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	intact-crc:85BF67338B849114|rigid:4Ux2lZd7WVnkni9ZNmkrgdE1ymY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q57159	uniprotkb:Q13315	intact:EBI-2853317|uniprotkb:Q74YE6|uniprotkb:Q7BTY0|uniprotkb:A0A3G5KYI6|uniprotkb:A0A0H2W0U5|uniprotkb:A0A2S9PAV7|uniprotkb:A0A380SC41	intact:EBI-495465|uniprotkb:O15429|uniprotkb:Q12758|uniprotkb:Q16551|uniprotkb:Q93007|uniprotkb:Q9NP02|uniprotkb:Q9UCX7|intact:EBI-1059333|uniprotkb:B2RNX5|ensembl:ENSP00000278616.4|ensembl:ENSP00000388058.2|ensembl:ENSP00000469471.2|ensembl:ENSP00000501606.1|ensembl:ENSP00000519149.1|intact:EBI-28985245	psi-mi:q57159_yerpe(display_long)|uniprotkb:pst(gene name)|psi-mi:pst(display_short)|uniprotkb:YPPCP1.05c(locus name)	psi-mi:atm_human(display_long)|uniprotkb:ATM(gene name)|psi-mi:ATM(display_short)|uniprotkb:Ataxia telangiectasia mutated(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875476|imex:IM-13779-8286	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023347|rcsb pdb:4AQN|rcsb pdb:4ARJ|rcsb pdb:4ARL|rcsb pdb:4ARM|rcsb pdb:4ARP|rcsb pdb:4ARQ|rcsb pdb:4EPF|rcsb pdb:4EPI|rcsb pdb:4EXM|refseq:NP_857783.1|interpro:IPR023346|refseq:NP_395231.1|refseq:YP_006960973.1|refseq:WP_002218509.1|interpro:IPR031922|go:""GO:0003796""(lysozyme activity)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0042742""(defense response to bacterium)|interpro:IPR033791"	"efo:""Orphanet:440437""|efo:""Orphanet:100""|efo:""Orphanet:1331""|efo:""Orphanet:370109""|efo:""Orphanet:52416""|efo:""Orphanet:67038""|ensembl:ENSG00000149311.22(gene)|ensembl:ENST00000278616.10(transcript)|ensembl:ENST00000452508.7(transcript)|ensembl:ENST00000601453.3(transcript)|ensembl:ENST00000675843.1(transcript)|ensembl:ENST00000713844.1(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000425""(pexophagy)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000729""(DNA double-strand break processing)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001756""(somitogenesis)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006974""(DNA damage response)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007131""(reciprocal meiotic recombination)|go:""GO:0007140""(male meiotic nuclear division)|go:""GO:0007143""(female meiotic nuclear division)|go:""GO:0007165""(signal transduction)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010212""(response to ionizing radiation)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016303""(1-phosphatidylinositol-3-kinase activity)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0032210""(regulation of telomere maintenance via telomerase)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0033151""(""V(D)J recombination"")|go:""GO:0033554""(cellular response to stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035861""(site of double-strand break)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0042159""(lipoprotein catabolic process)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043517""(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045141""(meiotic telomere clustering)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048538""(thymus development)|go:""GO:0048599""(oocyte development)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0071500""(cellular response to nitrosative stress)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090398""(cellular senescence)|go:""GO:0090399""(replicative senescence)|go:""GO:0097694""(establishment of RNA localization to telomere)|go:""GO:0097695""(establishment of protein-containing complex localization to telomere)|go:""GO:0098850""(extrinsic component of synaptic vesicle membrane)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1903626""(positive regulation of DNA catabolic process)|go:""GO:1903978""(regulation of microglial cell activation)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904354""(negative regulation of telomere capping)|go:""GO:1904358""(positive regulation of telomere maintenance via telomere lengthening)|go:""GO:1904884""(positive regulation of telomerase catalytic core complex assembly)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990391""(DNA repair complex)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021668|interpro:IPR036940|interpro:IPR038980|interpro:IPR044107|mint:Q13315|rcsb pdb:5NP0|rcsb pdb:5NP1|rcsb pdb:6HKA|rcsb pdb:6K9K|rcsb pdb:6K9L|rcsb pdb:7NI4|rcsb pdb:7NI5|rcsb pdb:7NI6|rcsb pdb:7SIC|rcsb pdb:7SID|rcsb pdb:8OXM|rcsb pdb:8OXO|rcsb pdb:8OXP|rcsb pdb:8OXQ|reactome:R-HSA-2559586|reactome:R-HSA-3371453|reactome:R-HSA-349425|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803207|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69473|reactome:R-HSA-69541|reactome:R-HSA-912446|reactome:R-HSA-9664873|reactome:R-HSA-9701192|reactome:R-HSA-9704331|reactome:R-HSA-9704646|reactome:R-HSA-9709570|reactome:R-HSA-9709603|refseq:NP_000042.3|refseq:XP_005271618.2|refseq:XP_005271619.2|refseq:XP_006718906.1|refseq:XP_006718908.1|refseq:XP_011541142.1|refseq:XP_016873278.1|refseq:XP_016873279.1|dip:DIP-182N|efo:""Orphanet:227535""|panther:PTHR11139(orthology-group)|ensembl:ENSP00000278616.4|ensembl:ENSP00000388058.2|ensembl:ENSP00000469471.2|ensembl:ENSP00000501606.1|ensembl:ENSP00000519149.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:lj4lgNanTASTf2Y+kd6biGud7vM632	rogid:d/FYo7KdBblfR/inXUZpFlWTfoo9606	intact-crc:97E461D50370DB92|rigid:6h+w89k1Vcmp8vvNKsufnon9a/w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CWH5	uniprotkb:Q99941	intact:EBI-2875497|uniprotkb:Q74UN5	intact:EBI-2841031|uniprotkb:Q99637|uniprotkb:Q5SSW7|uniprotkb:Q13269|uniprotkb:Q9H3W1|uniprotkb:Q9NPL0|uniprotkb:Q99635|uniprotkb:Q14345|uniprotkb:Q9H3V9|uniprotkb:B0UYX6|uniprotkb:Q14343|ensembl:ENSP00000293709.6|ensembl:ENSP00000364349.3|ensembl:ENSP00000404725.2|ensembl:ENSP00000404814.2	psi-mi:q8cwh5_yerpe(display_long)|uniprotkb:proP16(gene name)|psi-mi:proP16(display_short)|uniprotkb:YP_1674(locus name)|uniprotkb:y2379(locus name)	psi-mi:atf6b_human(display_long)|uniprotkb:ATF6B(gene name)|psi-mi:ATF6B(display_short)|uniprotkb:CREBL1(gene name synonym)|uniprotkb:G13(gene name synonym)|uniprotkb:Activating transcription factor 6 beta(gene name synonym)|uniprotkb:Protein G13(gene name synonym)|uniprotkb:cAMP response element-binding protein-related protein(gene name synonym)|uniprotkb:cAMP-responsive element-binding protein-like 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875502|imex:IM-13779-8287	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR036259"	"refseq:NP_001129625.1|refseq:NP_004372.3|ensembl:ENSG00000168468.12(gene)|ensembl:ENSG00000213676.13(gene)|ensembl:ENSG00000228628.8(gene)|ensembl:ENSG00000234539.9(gene)|ensembl:ENST00000293709.10(transcript)|ensembl:ENST00000375203.8(transcript)|ensembl:ENST00000425571.6(transcript)|ensembl:ENST00000427136.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007165""(signal transduction)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036500""(ATF6-mediated unfolded protein response)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903892""(negative regulation of ATF6-mediated unfolded protein response)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR046347|interpro:IPR051882|reactome:R-HSA-8874177|panther:PTHR46164(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ye3xrPDbbRb1kMVYpxNYI3ENSSs632	rogid:HEe34jikjdOE5qyUIfTFbAB5g3g9606	intact-crc:41FC0CCF38BB95F9|rigid:4zlc0xiTr+FHoEnVImi8gHqoVDA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UII2	uniprotkb:A0A5P8YAV7	intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203.5|ensembl:ENSP00000494248.1	intact:EBI-2839792|uniprotkb:Q74QU9|uniprotkb:Q0WA24|uniprotkb:Q7CG16|uniprotkb:A0A0H2W8V3	"psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:""Inhibitor of F(1)F(o)-ATPase""(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short)"	psi-mi:a0a5p8yav7_yerpe(display_long)|uniprotkb:pelY(gene name)|psi-mi:pelY(display_short)|uniprotkb:YPO3994(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875490|imex:IM-13779-8285	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770.18(gene)|ensembl:ENSG00000285390.2(gene)|ensembl:ENST00000335514.10(transcript)|ensembl:ENST00000647074.2(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0009986""(cell surface)|go:""GO:0019899""(enzyme binding)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042030""(ATPase inhibitor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043532""(angiostatin binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051346""(negative regulation of hydrolase activity)|go:""GO:0051882""(mitochondrial depolarization)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0140260""(mitochondrial proton-transporting ATP synthase complex binding)|go:""GO:1901030""(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1903052""(positive regulation of proteolysis involved in protein catabolic process)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|go:""GO:1903578""(regulation of ATP metabolic process)|go:""GO:1905091""(positive regulation of type 2 mitophagy)|go:""GO:1905707""(negative regulation of mitochondrial ATP synthesis coupled proton transport)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|rcsb pdb:8H9E|rcsb pdb:8H9L|rcsb pdb:8H9S|rcsb pdb:8H9U|rcsb pdb:8KI3|panther:PTHR23407(orthology-group)"	"interpro:IPR010702(Periplasmic pectate lyase)|refseq:YP_002348864.1|refseq:WP_002209555.1|go:""GO:0016837""(carbon-oxygen lyase activity, acting on polysaccharides)|go:""GO:0042597""(periplasmic space)|go:""GO:0045490""(pectin catabolic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606	rogid:TdSmcoWgW+r5eNyU5ieC4Vae68s632	intact-crc:14A4DDB401423B80|rigid:bxi6FM/mHqPwop0PGrPJKaYGNLc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBC2	uniprotkb:Q13315	intact:EBI-2851492|uniprotkb:Q0WBF3	intact:EBI-495465|uniprotkb:O15429|uniprotkb:Q12758|uniprotkb:Q16551|uniprotkb:Q93007|uniprotkb:Q9NP02|uniprotkb:Q9UCX7|intact:EBI-1059333|uniprotkb:B2RNX5|ensembl:ENSP00000278616.4|ensembl:ENSP00000388058.2|ensembl:ENSP00000469471.2|ensembl:ENSP00000501606.1|ensembl:ENSP00000519149.1|intact:EBI-28985245	psi-mi:if2_yerpe(display_long)|uniprotkb:infB(gene name)|psi-mi:infB(display_short)|uniprotkb:YPO3496(locus name)|uniprotkb:y0688(locus name)|uniprotkb:YP_0587(locus name)	psi-mi:atm_human(display_long)|uniprotkb:ATM(gene name)|psi-mi:ATM(display_short)|uniprotkb:Ataxia telangiectasia mutated(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875483|imex:IM-13779-8284	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002223151.1|interpro:IPR044145|interpro:IPR009061(Putative DNA binding)|interpro:IPR013575(Initiation factor 2 associated region, bacterial)|interpro:IPR006847(Translation initiation factor IF-2, N-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000178(Initiation factor 2)|interpro:IPR023115|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR015760(Translation initiation factor 2 related)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR036925|interpro:IPR053905|refseq:YP_002348385.1|panther:PTHR43381(orthology-group)"	"efo:""Orphanet:440437""|efo:""Orphanet:100""|efo:""Orphanet:1331""|efo:""Orphanet:370109""|efo:""Orphanet:52416""|efo:""Orphanet:67038""|ensembl:ENSG00000149311.22(gene)|ensembl:ENST00000278616.10(transcript)|ensembl:ENST00000452508.7(transcript)|ensembl:ENST00000601453.3(transcript)|ensembl:ENST00000675843.1(transcript)|ensembl:ENST00000713844.1(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000425""(pexophagy)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000729""(DNA double-strand break processing)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001756""(somitogenesis)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003677""(DNA binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006974""(DNA damage response)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0007131""(reciprocal meiotic recombination)|go:""GO:0007140""(male meiotic nuclear division)|go:""GO:0007143""(female meiotic nuclear division)|go:""GO:0007165""(signal transduction)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010212""(response to ionizing radiation)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016303""(1-phosphatidylinositol-3-kinase activity)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0032210""(regulation of telomere maintenance via telomerase)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0033151""(""V(D)J recombination"")|go:""GO:0033554""(cellular response to stress)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035861""(site of double-strand break)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0042159""(lipoprotein catabolic process)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043517""(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045141""(meiotic telomere clustering)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048538""(thymus development)|go:""GO:0048599""(oocyte development)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0071500""(cellular response to nitrosative stress)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090398""(cellular senescence)|go:""GO:0090399""(replicative senescence)|go:""GO:0097694""(establishment of RNA localization to telomere)|go:""GO:0097695""(establishment of protein-containing complex localization to telomere)|go:""GO:0098850""(extrinsic component of synaptic vesicle membrane)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1903626""(positive regulation of DNA catabolic process)|go:""GO:1903978""(regulation of microglial cell activation)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904354""(negative regulation of telomere capping)|go:""GO:1904358""(positive regulation of telomere maintenance via telomere lengthening)|go:""GO:1904884""(positive regulation of telomerase catalytic core complex assembly)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990391""(DNA repair complex)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR021668|interpro:IPR036940|interpro:IPR038980|interpro:IPR044107|mint:Q13315|rcsb pdb:5NP0|rcsb pdb:5NP1|rcsb pdb:6HKA|rcsb pdb:6K9K|rcsb pdb:6K9L|rcsb pdb:7NI4|rcsb pdb:7NI5|rcsb pdb:7NI6|rcsb pdb:7SIC|rcsb pdb:7SID|rcsb pdb:8OXM|rcsb pdb:8OXO|rcsb pdb:8OXP|rcsb pdb:8OXQ|reactome:R-HSA-2559586|reactome:R-HSA-3371453|reactome:R-HSA-349425|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803207|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69473|reactome:R-HSA-69541|reactome:R-HSA-912446|reactome:R-HSA-9664873|reactome:R-HSA-9701192|reactome:R-HSA-9704331|reactome:R-HSA-9704646|reactome:R-HSA-9709570|reactome:R-HSA-9709603|refseq:NP_000042.3|refseq:XP_005271618.2|refseq:XP_005271619.2|refseq:XP_006718906.1|refseq:XP_006718908.1|refseq:XP_011541142.1|refseq:XP_016873278.1|refseq:XP_016873279.1|dip:DIP-182N|efo:""Orphanet:227535""|panther:PTHR11139(orthology-group)|ensembl:ENSP00000278616.4|ensembl:ENSP00000388058.2|ensembl:ENSP00000469471.2|ensembl:ENSP00000501606.1|ensembl:ENSP00000519149.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:8Lhp4NihTUjn3nGZLA2K6kHbXg8632	rogid:d/FYo7KdBblfR/inXUZpFlWTfoo9606	intact-crc:8C35A8EB3C6109F9|rigid:UMoDkDzb6IxygNDySIA9xF7E4iM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZH96	uniprotkb:P18850	intact:EBI-2841438|uniprotkb:Q0WI34	intact:EBI-852157|uniprotkb:O15139|uniprotkb:Q5VW62|uniprotkb:Q6IPB5|uniprotkb:Q9UEC9|ensembl:ENSP00000356919.3|ensembl:ENSP00000505025.1|ensembl:ENSP00000505998.1	psi-mi:y1009_yerpe(display_long)|uniprotkb:YPO1009(locus name)|uniprotkb:y3403(locus name)|uniprotkb:YP_3421(locus name)	psi-mi:atf6a_human(display_long)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)|uniprotkb:ATF6(gene name)|psi-mi:ATF6(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875509|imex:IM-13779-8292	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR010161(Peptidase M20B, tripeptide aminopeptidase)|go:""GO:0006508""(proteolysis)|go:""GO:0006518""(peptide metabolic process)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0045148""(tripeptide aminopeptidase activity)|refseq:WP_002211633.1|refseq:YP_002346054.1|interpro:IPR036264"	"panther:PTHR46164(orthology-group)|ensembl:ENSG00000118217.7(gene)|ensembl:ENST00000367942.4(transcript)|ensembl:ENST00000681738.1(transcript)|ensembl:ENST00000681801.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001654""(eye development)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006457""(protein folding)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036500""(ATF6-mediated unfolded protein response)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903893""(positive regulation of ATF6-mediated unfolded protein response)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR046347|interpro:IPR051882|mint:P18850|reactome:R-HSA-380994|reactome:R-HSA-381033|reactome:R-HSA-381183|refseq:NP_031374.2|dip:DIP-29304N|efo:""Orphanet:1872""|efo:""Orphanet:49382"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Iu646Afihx3AH/xEVzu/jyKjYfI632	rogid:mIU7Apng6rQ423SQnZTsceVSRus9606	intact-crc:7B6925640E5124A1|rigid:5qkuE6DMsle45I0Nh2hmx9FrS5c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P18850	uniprotkb:A0A2U2GX99	intact:EBI-852157|uniprotkb:O15139|uniprotkb:Q5VW62|uniprotkb:Q6IPB5|uniprotkb:Q9UEC9|ensembl:ENSP00000356919.3|ensembl:ENSP00000505025.1|ensembl:ENSP00000505998.1	intact:EBI-2854330|uniprotkb:Q0WIX6|uniprotkb:Q7CGJ4|uniprotkb:A0A384L6K3	psi-mi:atf6a_human(display_long)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)|uniprotkb:ATF6(gene name)|psi-mi:ATF6(display_short)	psi-mi:a0a2u2gx99_yerpe(display_long)|uniprotkb:YPO0698(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875523|imex:IM-13779-8291	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR46164(orthology-group)|ensembl:ENSG00000118217.7(gene)|ensembl:ENST00000367942.4(transcript)|ensembl:ENST00000681738.1(transcript)|ensembl:ENST00000681801.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001654""(eye development)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006457""(protein folding)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036500""(ATF6-mediated unfolded protein response)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903893""(positive regulation of ATF6-mediated unfolded protein response)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR046347|interpro:IPR051882|mint:P18850|reactome:R-HSA-380994|reactome:R-HSA-381033|reactome:R-HSA-381183|refseq:NP_031374.2|dip:DIP-29304N|efo:""Orphanet:1872""|efo:""Orphanet:49382"""	"interpro:IPR042186|interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR025885|interpro:IPR025949|refseq:WP_002211458.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR037224|interpro:IPR043142|refseq:YP_002345762.1|panther:PTHR30451(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:mIU7Apng6rQ423SQnZTsceVSRus9606	rogid:JVraEv1dK3EeqcZNuRxbt8xrN34632	intact-crc:B4395B0E4D99EE6D|rigid:S8FI+zdJmpgATYiAePylqt7Zcxo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q74R28	uniprotkb:P15336	intact:EBI-2844649|uniprotkb:Q8D1I8	intact:EBI-1170906|uniprotkb:Q13000|uniprotkb:Q4ZFU9|uniprotkb:Q53RY2|uniprotkb:A1L3Z2|uniprotkb:D3DPE9|uniprotkb:Q8TAR1|uniprotkb:A4D7U4|uniprotkb:G8JLM5|uniprotkb:Q3B7B7|uniprotkb:A4D7U5|uniprotkb:A4D7V1|uniprotkb:Q96JT8|intact:EBI-28988937|ensembl:ENSP00000264110.2|ensembl:ENSP00000376327.1	psi-mi:ugpc_yerpe(display_long)|uniprotkb:ugpC(gene name)|psi-mi:ugpC(display_short)|uniprotkb:YPO3793(locus name)|uniprotkb:y0437(locus name)|uniprotkb:YP_3256(locus name)	psi-mi:atf2_human(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:CREB2(gene name synonym)|uniprotkb:CREBP1(gene name synonym)|uniprotkb:Activating transcription factor 2(gene name synonym)|uniprotkb:cAMP response element-binding protein CRE-BP1(gene name synonym)|uniprotkb:HB16(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875537|imex:IM-13779-8290	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR040582|interpro:IPR015855(ABC transporter, maltose/maltodextrin import, MalK)|interpro:IPR027417|refseq:WP_002211523.1|go:""GO:0001407""(glycerophosphodiester transmembrane transport)|go:""GO:0005524""(ATP binding)|go:""GO:0008643""(carbohydrate transport)|go:""GO:0015430""(ABC-type glycerol-3-phosphate transporter activity)|go:""GO:0015794""(glycerol-3-phosphate transmembrane transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055052""(""ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing"")|interpro:IPR047641|refseq:YP_002348670.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR43875(orthology-group)"	"refseq:NP_001243019.1|refseq:NP_001243020.1|refseq:NP_001871.2|refseq:NP_001243023.1|refseq:NP_001243021.1|refseq:NP_001243022.1|panther:PTHR19304(orthology-group)|dip:DIP-632N|ensembl:ENSG00000115966.18(gene)|ensembl:ENST00000264110.7(transcript)|ensembl:ENST00000392544.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001865""(NK T cell differentiation)|go:""GO:0001889""(liver development)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003360""(brainstem development)|go:""GO:0003418""(growth plate cartilage chondrocyte differentiation)|go:""GO:0003419""(growth plate cartilage chondrocyte proliferation)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0006974""(DNA damage response)|go:""GO:0007033""(vacuole organization)|go:""GO:0007254""(JNK cascade)|go:""GO:0008140""(cAMP response element binding protein binding)|go:""GO:0010485""(histone H4 acetyltransferase activity)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021742""(abducens nucleus development)|go:""GO:0021743""(hypoglossal nucleus development)|go:""GO:0021754""(facial nucleus development)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0031573""(mitotic intra-S DNA damage checkpoint signaling)|go:""GO:0032915""(positive regulation of transforming growth factor beta2 production)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035861""(site of double-strand break)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043522""(leucine zipper domain binding)|go:""GO:0044013""(histone H2B acetyltransferase activity)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050872""(white fat cell differentiation)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060052""(neurofilament cytoskeleton organization)|go:""GO:0060245""(detection of cell density)|go:""GO:0060612""(adipose tissue development)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0072740""(cellular response to anisomycin)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098586""(cellular response to virus)|go:""GO:0110024""(positive regulation of cardiac muscle myoblast proliferation)|go:""GO:1902110""(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902562""(H4 histone acetyltransferase complex)|go:""GO:1902742""(apoptotic process involved in development)|go:""GO:1990144""(intrinsic apoptotic signaling pathway in response to hypoxia)|go:""GO:1990253""(cellular response to leucine starvation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR036236|interpro:IPR046347|interpro:IPR051027|mint:P15336|rcsb pdb:1BHI|rcsb pdb:1T2K|rcsb pdb:4H36|rcsb pdb:6ZQS|rcsb pdb:6ZR5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-400253|reactome:R-HSA-450341|reactome:R-HSA-6796648|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9633012|reactome:R-HSA-9707616"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NtRUgbRI2HE2UzUkxbSvyMnRkao632	rogid:9krWq+A9Y3xvkInqyJnJs1g9tfc9606	intact-crc:D9F71454D7AE11A4|rigid:7aOQOIrt3R6bomTDKuyBRITUMM4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1A4	uniprotkb:P18850	intact:EBI-2850994	intact:EBI-852157|uniprotkb:O15139|uniprotkb:Q5VW62|uniprotkb:Q6IPB5|uniprotkb:Q9UEC9|ensembl:ENSP00000356919.3|ensembl:ENSP00000505025.1|ensembl:ENSP00000505998.1	psi-mi:q8d1a4_yerpe(display_long)|uniprotkb:y0798(locus name)|uniprotkb:fhuB(gene name)|psi-mi:fhuB(display_short)	psi-mi:atf6a_human(display_long)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)|uniprotkb:ATF6(gene name)|psi-mi:ATF6(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875516|imex:IM-13779-8288	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000522(Bacterial transport system permease protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR037294"	"panther:PTHR46164(orthology-group)|ensembl:ENSG00000118217.7(gene)|ensembl:ENST00000367942.4(transcript)|ensembl:ENST00000681738.1(transcript)|ensembl:ENST00000681801.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001654""(eye development)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006457""(protein folding)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036500""(ATF6-mediated unfolded protein response)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903893""(positive regulation of ATF6-mediated unfolded protein response)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR046347|interpro:IPR051882|mint:P18850|reactome:R-HSA-380994|reactome:R-HSA-381033|reactome:R-HSA-381183|refseq:NP_031374.2|dip:DIP-29304N|efo:""Orphanet:1872""|efo:""Orphanet:49382"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:PGAfc4VH09eJJH0aF+uMggT6rQg632	rogid:mIU7Apng6rQ423SQnZTsceVSRus9606	intact-crc:44657FDA0EF8DDCC|rigid:ZmbUXL+TOq4ahUycLYkq+nGbXQs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YAX4	uniprotkb:P18850	intact:EBI-2853387|uniprotkb:Q74QU2|uniprotkb:Q7CG20|uniprotkb:Q0WA17	intact:EBI-852157|uniprotkb:O15139|uniprotkb:Q5VW62|uniprotkb:Q6IPB5|uniprotkb:Q9UEC9|ensembl:ENSP00000356919.3|ensembl:ENSP00000505025.1|ensembl:ENSP00000505998.1	psi-mi:a0a5p8yax4_yerpe(display_long)|uniprotkb:dppA(gene name)|psi-mi:dppA(display_short)|uniprotkb:YPO4003(locus name)	psi-mi:atf6a_human(display_long)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)|uniprotkb:ATF6(gene name)|psi-mi:ATF6(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875530|imex:IM-13779-8289	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050017|interpro:IPR023765|interpro:IPR000914(Bacterial extracellular solute-binding protein, family 5)|interpro:IPR030678|refseq:WP_002209564.1|interpro:IPR039424|go:""GO:0015833""(peptide transport)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0042938""(dipeptide transport)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|go:""GO:0071916""(dipeptide transmembrane transporter activity)|go:""GO:1904680""(peptide transmembrane transporter activity)|refseq:YP_002348871.1|panther:PTHR30290(orthology-group)"	"panther:PTHR46164(orthology-group)|ensembl:ENSG00000118217.7(gene)|ensembl:ENST00000367942.4(transcript)|ensembl:ENST00000681738.1(transcript)|ensembl:ENST00000681801.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001654""(eye development)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006457""(protein folding)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036500""(ATF6-mediated unfolded protein response)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903893""(positive regulation of ATF6-mediated unfolded protein response)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR046347|interpro:IPR051882|mint:P18850|reactome:R-HSA-380994|reactome:R-HSA-381033|reactome:R-HSA-381183|refseq:NP_031374.2|dip:DIP-29304N|efo:""Orphanet:1872""|efo:""Orphanet:49382"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:cznt182D7L+5ZUpj1KCkFryJORE632	rogid:mIU7Apng6rQ423SQnZTsceVSRus9606	intact-crc:6F1B76588014C4B0|rigid:BBXPk0nrOwvEb9ZndxMG2HkSZxI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15336	uniprotkb:Q8D1D2	intact:EBI-1170906|uniprotkb:Q13000|uniprotkb:Q4ZFU9|uniprotkb:Q53RY2|uniprotkb:A1L3Z2|uniprotkb:D3DPE9|uniprotkb:Q8TAR1|uniprotkb:A4D7U4|uniprotkb:G8JLM5|uniprotkb:Q3B7B7|uniprotkb:A4D7U5|uniprotkb:A4D7V1|uniprotkb:Q96JT8|intact:EBI-28988937|ensembl:ENSP00000264110.2|ensembl:ENSP00000376327.1	intact:EBI-2849752|uniprotkb:Q74X70	psi-mi:atf2_human(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:CREB2(gene name synonym)|uniprotkb:CREBP1(gene name synonym)|uniprotkb:Activating transcription factor 2(gene name synonym)|uniprotkb:cAMP response element-binding protein CRE-BP1(gene name synonym)|uniprotkb:HB16(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)	psi-mi:q8d1d2_yerpe(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:y0687(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875544|imex:IM-13779-8293	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001243019.1|refseq:NP_001243020.1|refseq:NP_001871.2|refseq:NP_001243023.1|refseq:NP_001243021.1|refseq:NP_001243022.1|panther:PTHR19304(orthology-group)|dip:DIP-632N|ensembl:ENSG00000115966.18(gene)|ensembl:ENST00000264110.7(transcript)|ensembl:ENST00000392544.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001865""(NK T cell differentiation)|go:""GO:0001889""(liver development)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003360""(brainstem development)|go:""GO:0003418""(growth plate cartilage chondrocyte differentiation)|go:""GO:0003419""(growth plate cartilage chondrocyte proliferation)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0006974""(DNA damage response)|go:""GO:0007033""(vacuole organization)|go:""GO:0007254""(JNK cascade)|go:""GO:0008140""(cAMP response element binding protein binding)|go:""GO:0010485""(histone H4 acetyltransferase activity)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021742""(abducens nucleus development)|go:""GO:0021743""(hypoglossal nucleus development)|go:""GO:0021754""(facial nucleus development)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0031573""(mitotic intra-S DNA damage checkpoint signaling)|go:""GO:0032915""(positive regulation of transforming growth factor beta2 production)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035861""(site of double-strand break)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043522""(leucine zipper domain binding)|go:""GO:0044013""(histone H2B acetyltransferase activity)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050872""(white fat cell differentiation)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060052""(neurofilament cytoskeleton organization)|go:""GO:0060245""(detection of cell density)|go:""GO:0060612""(adipose tissue development)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0072740""(cellular response to anisomycin)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098586""(cellular response to virus)|go:""GO:0110024""(positive regulation of cardiac muscle myoblast proliferation)|go:""GO:1902110""(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902562""(H4 histone acetyltransferase complex)|go:""GO:1902742""(apoptotic process involved in development)|go:""GO:1990144""(intrinsic apoptotic signaling pathway in response to hypoxia)|go:""GO:1990253""(cellular response to leucine starvation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR036236|interpro:IPR046347|interpro:IPR051027|mint:P15336|rcsb pdb:1BHI|rcsb pdb:1T2K|rcsb pdb:4H36|rcsb pdb:6ZQS|rcsb pdb:6ZR5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-400253|reactome:R-HSA-450341|reactome:R-HSA-6796648|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9633012|reactome:R-HSA-9707616"	"interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010214(Transcription termination factor NusA, C-terminal duplication)|interpro:IPR010213(Transcription termination factor NusA)|interpro:IPR025249|interpro:IPR030842|go:""GO:0000166""(nucleotide binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|interpro:IPR036555"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9krWq+A9Y3xvkInqyJnJs1g9tfc9606	rogid:YzZfDXwWbJbXKFeHL1SADDhW96Q632	intact-crc:1A10F8FD0AE3397F|rigid:6LsRHWRQTxLpJFToWyiiO6U/2AI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15336	uniprotkb:A0A5P8YJE6	intact:EBI-1170906|uniprotkb:Q13000|uniprotkb:Q4ZFU9|uniprotkb:Q53RY2|uniprotkb:A1L3Z2|uniprotkb:D3DPE9|uniprotkb:Q8TAR1|uniprotkb:A4D7U4|uniprotkb:G8JLM5|uniprotkb:Q3B7B7|uniprotkb:A4D7U5|uniprotkb:A4D7V1|uniprotkb:Q96JT8|intact:EBI-28988937|ensembl:ENSP00000264110.2|ensembl:ENSP00000376327.1	intact:EBI-2841894|uniprotkb:Q74WV5|uniprotkb:A0A384KGR0|uniprotkb:Q0WC78|uniprotkb:Q7CK53	psi-mi:atf2_human(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:CREB2(gene name synonym)|uniprotkb:CREBP1(gene name synonym)|uniprotkb:Activating transcription factor 2(gene name synonym)|uniprotkb:cAMP response element-binding protein CRE-BP1(gene name synonym)|uniprotkb:HB16(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)	psi-mi:a0a5p8yje6_yerpe(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:YPO3206(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875551|imex:IM-13779-8295	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001243019.1|refseq:NP_001243020.1|refseq:NP_001871.2|refseq:NP_001243023.1|refseq:NP_001243021.1|refseq:NP_001243022.1|panther:PTHR19304(orthology-group)|dip:DIP-632N|ensembl:ENSG00000115966.18(gene)|ensembl:ENST00000264110.7(transcript)|ensembl:ENST00000392544.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001865""(NK T cell differentiation)|go:""GO:0001889""(liver development)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003360""(brainstem development)|go:""GO:0003418""(growth plate cartilage chondrocyte differentiation)|go:""GO:0003419""(growth plate cartilage chondrocyte proliferation)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0006974""(DNA damage response)|go:""GO:0007033""(vacuole organization)|go:""GO:0007254""(JNK cascade)|go:""GO:0008140""(cAMP response element binding protein binding)|go:""GO:0010485""(histone H4 acetyltransferase activity)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021742""(abducens nucleus development)|go:""GO:0021743""(hypoglossal nucleus development)|go:""GO:0021754""(facial nucleus development)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0031573""(mitotic intra-S DNA damage checkpoint signaling)|go:""GO:0032915""(positive regulation of transforming growth factor beta2 production)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035861""(site of double-strand break)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043522""(leucine zipper domain binding)|go:""GO:0044013""(histone H2B acetyltransferase activity)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050872""(white fat cell differentiation)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060052""(neurofilament cytoskeleton organization)|go:""GO:0060245""(detection of cell density)|go:""GO:0060612""(adipose tissue development)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0072740""(cellular response to anisomycin)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098586""(cellular response to virus)|go:""GO:0110024""(positive regulation of cardiac muscle myoblast proliferation)|go:""GO:1902110""(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902562""(H4 histone acetyltransferase complex)|go:""GO:1902742""(apoptotic process involved in development)|go:""GO:1990144""(intrinsic apoptotic signaling pathway in response to hypoxia)|go:""GO:1990253""(cellular response to leucine starvation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR036236|interpro:IPR046347|interpro:IPR051027|mint:P15336|rcsb pdb:1BHI|rcsb pdb:1T2K|rcsb pdb:4H36|rcsb pdb:6ZQS|rcsb pdb:6ZR5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-400253|reactome:R-HSA-450341|reactome:R-HSA-6796648|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9633012|reactome:R-HSA-9707616"	"interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|interpro:IPR026843|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004529""(DNA exonuclease activity)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0008408""(3'-5' exonuclease activity)|refseq:YP_002348110.1|interpro:IPR041796|refseq:WP_002208687.1|interpro:IPR050535|panther:PTHR30337(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9krWq+A9Y3xvkInqyJnJs1g9tfc9606	rogid:cU2EtOzG4AsrqZc2Mw4GEGw7+Mo632	intact-crc:B03ECB4B9CDC45B5|rigid:QCKzT7O55hTyH48L4V+jHfIlTns	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKF8	uniprotkb:Q8IXJ9	intact:EBI-2844579|uniprotkb:Q74RR5	intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839.4	psi-mi:q8ckf8_yerpe(display_long)|uniprotkb:y3542(locus name)	psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875565|imex:IM-13779-8294	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR037883	"dip:DIP-46910N|ensembl:ENSG00000171456.22(gene)|ensembl:ENST00000375687.10(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0030097""(hemopoiesis)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0035359""(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:""GO:0035517""(PR-DUB complex)|go:""GO:0035564""(regulation of kidney size)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0042975""(peroxisome proliferator activated receptor binding)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048386""(positive regulation of retinoic acid receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0048539""(bone marrow development)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0060430""(lung saccule development)|go:""GO:0072015""(podocyte development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|mint:Q8IXJ9|rcsb pdb:8H1T|rcsb pdb:8SVF|reactome:R-HSA-5689603|refseq:NP_056153.2|efo:""Orphanet:86845""|efo:""Orphanet:97297""|efo:""Orphanet:98823""|efo:""Orphanet:98849""|efo:""Orphanet:98850""|ensembl:ENSP00000364839.4|panther:PTHR13578(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/05	rogid:bULfeL7EI8ZLrm+OLqILFkvARMg632	rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606	intact-crc:A44313948FBCBA15|rigid:SrcW3TYn7LsQJkJLX140YCkDSt8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W8I7	uniprotkb:P15336	intact:EBI-2845372|uniprotkb:Q74PX7|uniprotkb:Q0WJN8|uniprotkb:Q7CG54|uniprotkb:A0A3N4B192|uniprotkb:A0A384KPY8	intact:EBI-1170906|uniprotkb:Q13000|uniprotkb:Q4ZFU9|uniprotkb:Q53RY2|uniprotkb:A1L3Z2|uniprotkb:D3DPE9|uniprotkb:Q8TAR1|uniprotkb:A4D7U4|uniprotkb:G8JLM5|uniprotkb:Q3B7B7|uniprotkb:A4D7U5|uniprotkb:A4D7V1|uniprotkb:Q96JT8|intact:EBI-28988937|ensembl:ENSP00000264110.2|ensembl:ENSP00000376327.1	psi-mi:a0a0h2w8i7_yerpe(display_long)|uniprotkb:YPO0424(locus name)	psi-mi:atf2_human(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:CREB2(gene name synonym)|uniprotkb:CREBP1(gene name synonym)|uniprotkb:Activating transcription factor 2(gene name synonym)|uniprotkb:cAMP response element-binding protein CRE-BP1(gene name synonym)|uniprotkb:HB16(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875558|imex:IM-13779-8296	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR000070(Pectinesterase, catalytic)|go:""GO:0030599""(pectinesterase activity)|go:""GO:0042545""(cell wall modification)|refseq:WP_002209202.1|refseq:YP_002345500.1"	"refseq:NP_001243019.1|refseq:NP_001243020.1|refseq:NP_001871.2|refseq:NP_001243023.1|refseq:NP_001243021.1|refseq:NP_001243022.1|panther:PTHR19304(orthology-group)|dip:DIP-632N|ensembl:ENSG00000115966.18(gene)|ensembl:ENST00000264110.7(transcript)|ensembl:ENST00000392544.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001865""(NK T cell differentiation)|go:""GO:0001889""(liver development)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003360""(brainstem development)|go:""GO:0003418""(growth plate cartilage chondrocyte differentiation)|go:""GO:0003419""(growth plate cartilage chondrocyte proliferation)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006970""(response to osmotic stress)|go:""GO:0006974""(DNA damage response)|go:""GO:0007033""(vacuole organization)|go:""GO:0007254""(JNK cascade)|go:""GO:0008140""(cAMP response element binding protein binding)|go:""GO:0010485""(histone H4 acetyltransferase activity)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0018107""(peptidyl-threonine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021742""(abducens nucleus development)|go:""GO:0021743""(hypoglossal nucleus development)|go:""GO:0021754""(facial nucleus development)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0031573""(mitotic intra-S DNA damage checkpoint signaling)|go:""GO:0032915""(positive regulation of transforming growth factor beta2 production)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035861""(site of double-strand break)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043522""(leucine zipper domain binding)|go:""GO:0044013""(histone H2B acetyltransferase activity)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050872""(white fat cell differentiation)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060052""(neurofilament cytoskeleton organization)|go:""GO:0060245""(detection of cell density)|go:""GO:0060612""(adipose tissue development)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0072740""(cellular response to anisomycin)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:0098586""(cellular response to virus)|go:""GO:0110024""(positive regulation of cardiac muscle myoblast proliferation)|go:""GO:1902110""(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902562""(H4 histone acetyltransferase complex)|go:""GO:1902742""(apoptotic process involved in development)|go:""GO:1990144""(intrinsic apoptotic signaling pathway in response to hypoxia)|go:""GO:1990253""(cellular response to leucine starvation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR036236|interpro:IPR046347|interpro:IPR051027|mint:P15336|rcsb pdb:1BHI|rcsb pdb:1T2K|rcsb pdb:4H36|rcsb pdb:6ZQS|rcsb pdb:6ZR5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-400253|reactome:R-HSA-450341|reactome:R-HSA-6796648|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9633012|reactome:R-HSA-9707616"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZR0NI1QExt1ZKI/z7ydFgfe5LS4632	rogid:9krWq+A9Y3xvkInqyJnJs1g9tfc9606	intact-crc:9CAF6C785F1B7C68|rigid:zlfMLkZae+uVhsu/CSwI+avnijk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKF8	uniprotkb:Q96KQ4	intact:EBI-2844579|uniprotkb:Q74RR5	intact:EBI-1105153|uniprotkb:B2RMX5|uniprotkb:O94870|ensembl:ENSP00000202556.9	psi-mi:q8ckf8_yerpe(display_long)|uniprotkb:y3542(locus name)	psi-mi:aspp1_human(display_long)|uniprotkb:PPP1R13B(gene name)|psi-mi:PPP1R13B(display_short)|uniprotkb:ASPP1(gene name synonym)|uniprotkb:KIAA0771(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 13B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875601|imex:IM-13779-8299	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR037883	"refseq:NP_056131.2|ensembl:ENSG00000088808.18(gene)|ensembl:ENST00000202556.14(transcript)|go:""GO:0002039""(p53 binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR028319|interpro:IPR029071|interpro:IPR036028|interpro:IPR036770|interpro:IPR047163|interpro:IPR048942|mint:Q96KQ4|rcsb pdb:6HL5|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803211|reactome:R-HSA-6804759|panther:PTHR24131(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bULfeL7EI8ZLrm+OLqILFkvARMg632	rogid:68vrjCXCm2NiwUih4QbAqeT3Jj49606	intact-crc:05B7388DDFCE1157|rigid:LsVm9pvTLBeBL5LCk9lfN/kr9ew	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IXJ9	uniprotkb:Q0WKG1	intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839.4	intact:EBI-2855083|uniprotkb:Q74Y36|uniprotkb:A0A0H2W137|uniprotkb:A0A3N4AZM6|uniprotkb:Q7CFW7|uniprotkb:A0A384L9U0	psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym)	psi-mi:q0wkg1_yerpe(display_long)|uniprotkb:YPO0141(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875579|imex:IM-13779-8300	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-46910N|ensembl:ENSG00000171456.22(gene)|ensembl:ENST00000375687.10(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0030097""(hemopoiesis)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0035359""(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:""GO:0035517""(PR-DUB complex)|go:""GO:0035564""(regulation of kidney size)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0042975""(peroxisome proliferator activated receptor binding)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048386""(positive regulation of retinoic acid receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0048539""(bone marrow development)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0060430""(lung saccule development)|go:""GO:0072015""(podocyte development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|mint:Q8IXJ9|rcsb pdb:8H1T|rcsb pdb:8SVF|reactome:R-HSA-5689603|refseq:NP_056153.2|efo:""Orphanet:86845""|efo:""Orphanet:97297""|efo:""Orphanet:98823""|efo:""Orphanet:98849""|efo:""Orphanet:98850""|ensembl:ENSP00000364839.4|panther:PTHR13578(orthology-group)"	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|refseq:WP_002208909.1|go:""GO:0046872""(metal ion binding)|interpro:IPR050155|interpro:IPR036412|refseq:YP_002345227.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/05	rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606	rogid:C2n5rHIofpB8tAA4iKdS/lm5nZ4632	intact-crc:8D9A37AB0507E25C|rigid:G+FtovCKpAA6r1ZEvFCOGuz0EhQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q2TB18	uniprotkb:P17778	intact:EBI-2875586|ensembl:ENSP00000264992.3|uniprotkb:Q9UHX6|uniprotkb:Q3MIB6|uniprotkb:Q96JY1|uniprotkb:Q8N6G4|uniprotkb:B4DFL9	intact:EBI-2842665|uniprotkb:O68701	psi-mi:aste1_human(display_long)|uniprotkb:Protein asteroid homolog 1(gene name synonym)|uniprotkb:HT001(orf name)|uniprotkb:ASTE1(gene name)|psi-mi:ASTE1(display_short)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875594|imex:IM-13779-8298	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000034533.12(gene)|ensembl:ENST00000264992.8(transcript)|go:""GO:0000014""(single-stranded DNA endodeoxyribonuclease activity)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:1990599""(3' overhang single-stranded DNA endodeoxyribonuclease activity)|interpro:IPR006085(XPG N-terminal)|interpro:IPR026832|interpro:IPR029060|refseq:NP_054784.2|refseq:NP_001275879.1|refseq:XP_016861755.1|refseq:XP_016861756.1|refseq:XP_016861757.1|refseq:XP_016861758.1|panther:PTHR15665(orthology-group)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ufFKH6sCVo/EbBca0tHBtvZju+k9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:BE71663A94CF41DD|rigid:PRK5vP/JT1Sa3C4SmMU8BcE31cg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IXJ9	uniprotkb:A0A2U2GZB5	intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839.4	intact:EBI-2846673|uniprotkb:Q74QD5|uniprotkb:Q0WII4|uniprotkb:Q7CGV8|uniprotkb:A0A3N4B688|uniprotkb:A0A384LH97	psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym)	psi-mi:a0a2u2gzb5_yerpe(display_long)|uniprotkb:YPO0853(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875572|imex:IM-13779-8297	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-46910N|ensembl:ENSG00000171456.22(gene)|ensembl:ENST00000375687.10(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0030097""(hemopoiesis)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0035359""(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:""GO:0035517""(PR-DUB complex)|go:""GO:0035564""(regulation of kidney size)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0042975""(peroxisome proliferator activated receptor binding)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048386""(positive regulation of retinoic acid receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0048539""(bone marrow development)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0060430""(lung saccule development)|go:""GO:0072015""(podocyte development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|mint:Q8IXJ9|rcsb pdb:8H1T|rcsb pdb:8SVF|reactome:R-HSA-5689603|refseq:NP_056153.2|efo:""Orphanet:86845""|efo:""Orphanet:97297""|efo:""Orphanet:98823""|efo:""Orphanet:98849""|efo:""Orphanet:98850""|ensembl:ENSP00000364839.4|panther:PTHR13578(orthology-group)"	"interpro:IPR011683(Glycosyl hydrolase 53)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209898.1|go:""GO:0015926""(glucosidase activity)|refseq:YP_002345904.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/05	rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606	rogid:vZspj0o9Xm28cUFYlvj9K2v6gM8632	intact-crc:3CBACF897299A5FD|rigid:aqASQGq/GfdaOM61cgOtJLlZA9c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NR48	uniprotkb:Q0W9W3	intact:EBI-2875611|ensembl:ENSP00000357330.3|intact:EBI-28969209|uniprotkb:Q9P2C7|uniprotkb:Q5T715|uniprotkb:Q5T714|uniprotkb:Q59GP1	intact:EBI-2850864|uniprotkb:Q74PD6|uniprotkb:A0A0H2W8D7|uniprotkb:A0A380PJZ2|uniprotkb:Q7CFP7|uniprotkb:A0A384K9N9	psi-mi:ash1l_human(display_long)|uniprotkb:ASH1L(gene name)|psi-mi:ASH1L(display_short)|uniprotkb:KIAA1420(gene name synonym)|uniprotkb:KMT2H(gene name synonym)|uniprotkb:ASH1-like protein(gene name synonym)|uniprotkb:Absent small and homeotic disks protein 1 homolog(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2H(gene name synonym)	psi-mi:q0w9w3_yerpe(display_long)|uniprotkb:mtlA(gene name)|psi-mi:mtlA(display_short)|uniprotkb:EIICBA-Mtl(gene name synonym)|uniprotkb:YPO4068(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875608|imex:IM-13779-8301	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000116539.14(gene)|ensembl:ENST00000368346.7(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001501""(skeletal system development)|go:""GO:0002674""(negative regulation of acute inflammatory response)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0007338""(single fertilization)|go:""GO:0009791""(post-embryonic development)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0032259""(methylation)|go:""GO:0042800""(histone H3K4 methyltransferase activity)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046697""(decidualization)|go:""GO:0046872""(metal ion binding)|go:""GO:0046974""(histone H3K9 methyltransferase activity)|go:""GO:0046975""(histone H3K36 methyltransferase activity)|go:""GO:0061038""(uterus morphogenesis)|go:""GO:0140938""(histone H3 methyltransferase activity)|go:""GO:0140947""(histone H3K9me2 methyltransferase activity)|go:""GO:0140948""(histone H3K9 monomethyltransferase activity)|go:""GO:0140955""(histone H3K36 trimethyltransferase activity)|go:""GO:1903699""(tarsal gland development)|go:""GO:1903709""(uterine gland development)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017956|interpro:IPR019786|interpro:IPR036427|interpro:IPR043151|interpro:IPR043319|interpro:IPR043320|interpro:IPR046341|mint:Q9NR48|rcsb pdb:3MQM|rcsb pdb:3OPE|rcsb pdb:4YNM|rcsb pdb:4YNP|rcsb pdb:4YPA|rcsb pdb:4YPE|rcsb pdb:4YPU|rcsb pdb:6AGO|rcsb pdb:6INE|rcsb pdb:6WZW|rcsb pdb:6X0P|rcsb pdb:7Y0I|reactome:R-HSA-3214841|refseq:NP_060959.2|refseq:XP_006711513.1|refseq:XP_006711514.1|refseq:XP_016857273.1|refseq:XP_016857274.1|efo:""Orphanet:178469""|panther:PTHR46147(orthology-group)"	"interpro:IPR013011(Phosphotransferase system, EIIB component, type 2)|interpro:IPR013014(Phosphotransferase system, EIIC component, type 2)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|interpro:IPR003501(Phosphotransferase system, lactose/cellobiose-specific IIB subunit)|interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR004718(Phosphotransferase system, mannitol-specific enzyme IIC)|interpro:IPR029503|refseq:WP_002209621.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0022872""(""protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity"")|interpro:IPR036095|refseq:YP_002348925.1|interpro:IPR050893"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nHVsMYk/nMjaouiONirt9UwoS+49606	rogid:IRMdiu3ZdRcaOFT1CtHmg2fPok8632	intact-crc:936B89AD1E969951|rigid:yXRgnDE//u3O/e9UA7CYnGYfexM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZE20	uniprotkb:Q9BXP5	intact:EBI-2857666|uniprotkb:Q74TK0|uniprotkb:Q0WEF3|uniprotkb:Q8D0L4	intact:EBI-712721|uniprotkb:A4D2E5|uniprotkb:A6NK22|uniprotkb:Q32MI4|uniprotkb:Q9Y4S4|uniprotkb:O95808|uniprotkb:Q9BWP6|uniprotkb:Q9BXP4|uniprotkb:A4D2E6|uniprotkb:B4DJL4|uniprotkb:B4DZA6|uniprotkb:Q6NT74|uniprotkb:Q8TDQ5|ensembl:ENSP00000480421.1	psi-mi:syy_yerpe(display_long)|uniprotkb:tyrS(gene name)|psi-mi:tyrS(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO2369(locus name)|uniprotkb:YP_2155(locus name)|uniprotkb:y1966(locus name)	psi-mi:srrt_human(display_long)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ASR2(gene name synonym)|uniprotkb:ARS2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875651|imex:IM-13779-8303	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002942(RNA-binding S4)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR024088|interpro:IPR024107|refseq:WP_002210960.1|go:""GO:0003723""(RNA binding)|go:""GO:0004831""(tyrosine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006437""(tyrosyl-tRNA aminoacylation)|go:""GO:0043039""(tRNA aminoacylation)|interpro:IPR054608|interpro:IPR036986|refseq:YP_002347335.1|panther:PTHR11766(orthology-group)"	"refseq:NP_001122324.1|refseq:NP_001122325.1|refseq:NP_001122326.1|refseq:NP_056992.4|ensembl:ENSG00000087087.20(gene)|ensembl:ENST00000611405.5(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0016604""(nuclear body)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031053""(primary miRNA processing)|go:""GO:0032991""(protein-containing complex)|go:""GO:0046685""(response to arsenic-containing substance)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0140262""(mRNA cap binding complex binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q9BXP5|rcsb pdb:5OO6|rcsb pdb:6F7J|rcsb pdb:6F7P|rcsb pdb:6F7S|rcsb pdb:6F8D|rcsb pdb:8PMP|reactome:R-HSA-6807505|reactome:R-HSA-72163|panther:PTHR13165(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BUagKLSbiLvLgJHoonFfm7nI4ss632	rogid:upRnTwa7LTUzxnbGtfpJUejg2+w9606	intact-crc:6DC0E15FF5376CA3|rigid:o+9yrrlXPWHsiEUNyy8p4KYq4J0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BXP5	uniprotkb:A0A5P8YGX7	intact:EBI-712721|uniprotkb:A4D2E5|uniprotkb:A6NK22|uniprotkb:Q32MI4|uniprotkb:Q9Y4S4|uniprotkb:O95808|uniprotkb:Q9BWP6|uniprotkb:Q9BXP4|uniprotkb:A4D2E6|uniprotkb:B4DJL4|uniprotkb:B4DZA6|uniprotkb:Q6NT74|uniprotkb:Q8TDQ5|ensembl:ENSP00000480421.1	intact:EBI-2851265|uniprotkb:Q74T83|uniprotkb:Q0WE33|uniprotkb:Q7CJ53|uniprotkb:A0A384KBR0	psi-mi:srrt_human(display_long)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ASR2(gene name synonym)|uniprotkb:ARS2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym)	psi-mi:a0a5p8ygx7_yerpe(display_long)|uniprotkb:YPO2491(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875658|imex:IM-13779-8305	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122324.1|refseq:NP_001122325.1|refseq:NP_001122326.1|refseq:NP_056992.4|ensembl:ENSG00000087087.20(gene)|ensembl:ENST00000611405.5(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0016604""(nuclear body)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031053""(primary miRNA processing)|go:""GO:0032991""(protein-containing complex)|go:""GO:0046685""(response to arsenic-containing substance)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0140262""(mRNA cap binding complex binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q9BXP5|rcsb pdb:5OO6|rcsb pdb:6F7J|rcsb pdb:6F7P|rcsb pdb:6F7S|rcsb pdb:6F8D|rcsb pdb:8PMP|reactome:R-HSA-6807505|reactome:R-HSA-72163|panther:PTHR13165(orthology-group)"	"interpro:IPR027282|interpro:IPR034746|interpro:IPR005565(Haemolysin activator HlyB)|interpro:IPR013686(Polypeptide-transport-associated, ShlB-type)|interpro:IPR035251|refseq:WP_002210212.1|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046819""(protein secretion by the type V secretion system)|go:""GO:0098046""(type V protein secretion system complex)|refseq:YP_002347455.1|interpro:IPR051544|panther:PTHR34597(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:upRnTwa7LTUzxnbGtfpJUejg2+w9606	rogid:OGj9bfN4PBupBxOaODA+a4060Uw632	intact-crc:71280D9B082EFC29|rigid:OSWW6HAhlgI0M9i9Ynhv/yYI7Wk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y575	uniprotkb:Q8ZBN2	intact:EBI-2875625|ensembl:ENSP00000263634.2|ensembl:ENSP00000385085.4|uniprotkb:Q53TN8|uniprotkb:Q53TN0|uniprotkb:B3KPA3|uniprotkb:Q9NVZ2|uniprotkb:D6W5B4|uniprotkb:D6W5B5|uniprotkb:G8JLA9|uniprotkb:Q2TAI4	intact:EBI-2866457|uniprotkb:Q0WBS0	psi-mi:asb3_human(display_long)|uniprotkb:ASB3(gene name)|psi-mi:ASB3(display_short)	psi-mi:eno_yerpe(display_long)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:YPO3376(locus name)|uniprotkb:y0814(locus name)|uniprotkb:YP_0310(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875633|imex:IM-13779-8304	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115239.24(gene)|ensembl:ENST00000263634.8(transcript)|ensembl:ENST00000406625.6(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030315""(T-tubule)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036371""(protein localization to T-tubule)|go:""GO:0055117""(regulation of cardiac muscle contraction)|go:""GO:1904108""(protein localization to ciliary inversin compartment)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR036036|interpro:IPR036770|interpro:IPR037329|mint:Q9Y575|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001188894.1|refseq:NP_057199.1|refseq:NP_665862.1|refseq:NP_001157637.1|panther:PTHR24178(orthology-group)"	"interpro:IPR000941(Enolase)|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|refseq:WP_002209377.1|go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006096""(glycolytic process)|go:""GO:0009986""(cell surface)|refseq:YP_002348268.1|panther:PTHR11902(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gIMKRtUzf90UdaMhaSwEmesN+KE9606	rogid:Wv24HGwqOUCul2bvS0kXRmQ7uR0632	intact-crc:5B764582AFE4F288|rigid:OKI+79miIYFM2uCavjoe8fy7AZQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15289	uniprotkb:Q8CZH7	intact:EBI-2117357|uniprotkb:Q6ICI5|uniprotkb:Q96CJ0|uniprotkb:B2RCA6|uniprotkb:F8WCC8|uniprotkb:B7XD04	intact:EBI-2875640	psi-mi:arsa_human(display_long)|uniprotkb:ARSA(gene name)|psi-mi:ARSA(display_short)|uniprotkb:Cerebroside-sulfatase(gene name synonym)	psi-mi:q8czh7_yerpe(display_long)|uniprotkb:xylB(gene name)|psi-mi:xylB(display_short)|uniprotkb:y4058(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875644|imex:IM-13779-8302	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR42693(orthology-group)|efo:""Orphanet:309256""|efo:""Orphanet:309263""|efo:""Orphanet:309271""|go:""GO:0004065""(arylsulfatase activity)|go:""GO:0004098""(cerebroside-sulfatase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005764""(lysosome)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0008484""(sulfuric ester hydrolase activity)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000917(Sulphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR024607|interpro:IPR050738|mint:P15289|rcsb pdb:1AUK|rcsb pdb:1E1Z|rcsb pdb:1E2S|rcsb pdb:1E33|rcsb pdb:1E3C|rcsb pdb:1N2K|rcsb pdb:1N2L|rcsb pdb:2AIJ|rcsb pdb:2AIK|rcsb pdb:2HI8|reactome:R-HSA-1663150|reactome:R-HSA-6798695|reactome:R-HSA-9840310|refseq:NP_000478.3|refseq:NP_001078894.2|refseq:NP_001078895.2|refseq:NP_001078896.2|refseq:NP_001078897.1|refseq:XP_011528992.1"	"go:""GO:0004856""(D-xylulokinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005998""(xylulose catabolic process)|go:""GO:0042732""(D-xylose metabolic process)|refseq:WP_002231670.1|interpro:IPR018485|interpro:IPR018483|interpro:IPR018484|interpro:IPR006000(Xylulokinase)|interpro:IPR000577(Carbohydrate kinase, FGGY)|interpro:IPR043129|interpro:IPR050406"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:r9aHZqERfWNUy9m6C0DG2pCtsEs9606	rogid:MObnL/qaoqllrDxzCD3LzqInvhE632	intact-crc:7118129018640401|rigid:TMgUbarccy7g3o5IQd2x+rs8k5M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P59998	uniprotkb:A0A5P8YAM6	intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|uniprotkb:F6TTL5|ensembl:ENSP00000380431.2	intact:EBI-2844150|uniprotkb:Q7CFP2|uniprotkb:Q0W9V4	psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym)	psi-mi:a0a5p8yam6_yerpe(display_long)|uniprotkb:malS(gene name)|psi-mi:malS(display_short)|uniprotkb:YPO4080(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875703|imex:IM-13779-8307	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:662762""|ensembl:ENSG00000241553.13(gene)|ensembl:ENST00000397261.8(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0019899""(enzyme binding)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042995""(cell projection)|go:""GO:0045010""(actin nucleation)|go:""GO:0070062""(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|refseq:NP_001185709.1|refseq:NP_005709.1|dip:DIP-33188N|panther:PTHR22629(orthology-group)"	"interpro:IPR014635(Alpha-amylase, MalS type)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209631.1|go:""GO:0004556""(alpha-amylase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0009313""(oligosaccharide catabolic process)|go:""GO:0030980""(alpha-glucan catabolic process)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348934.1|panther:PTHR10357(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606	rogid:qjQekYtSF56tT51Uzp+xShmXohk632	intact-crc:58F8E4CC19B554EB|rigid:tNOB+RWjZ/3Qxkc6xQbB8zKHb3w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P58722	uniprotkb:Q96B67	intact:EBI-2875681|uniprotkb:Q0WKG0	intact:EBI-2875665|intact:EBI-28982382|ensembl:ENSP00000265138.3|uniprotkb:A8K6T8|uniprotkb:Q9P2H1	psi-mi:igaa_yerpe(display_long)|uniprotkb:YPO0142(locus name)|uniprotkb:y3922(locus name)|uniprotkb:YP_0143(locus name)	psi-mi:arrd3_human(display_long)|uniprotkb:KIAA1376(gene name synonym)|uniprotkb:TBP-2-like inducible membrane protein(gene name synonym)|uniprotkb:ARRDC3(gene name)|psi-mi:ARRDC3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875678|imex:IM-13779-8306	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|interpro:IPR010771(Intracellular growth attenuator IgaA)|refseq:WP_002208908.1|refseq:YP_002345228.1"	"ensembl:ENSG00000113369.9(gene)|ensembl:ENST00000265138.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|go:""GO:0031649""(heat generation)|go:""GO:0031651""(negative regulation of heat generation)|go:""GO:0031699""(beta-3 adrenergic receptor binding)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0043588""(skin development)|go:""GO:0051443""(positive regulation of ubiquitin-protein transferase activity)|go:""GO:0060613""(fat pad development)|go:""GO:0071878""(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway)|go:""GO:0090327""(negative regulation of locomotion involved in locomotory behavior)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR050357|mint:Q96B67|rcsb pdb:4N7H|rcsb pdb:4R7V|rcsb pdb:4R7X|refseq:NP_065852.1|panther:PTHR11188(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VvYIPk2pP31zS/asg/V6kBCljsA632	rogid:XPgatMsOEeWbHJXTkQZsNXaWuNs9606	intact-crc:3CDA76A766B90469|rigid:GiaFtleaKciOiC9L4Ia35KeaRl4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJN4	uniprotkb:Q96B67	intact:EBI-2875692|uniprotkb:Q74YA1|uniprotkb:Q0WKN4|uniprotkb:Q8D1S5	intact:EBI-2875665|intact:EBI-28982382|ensembl:ENSP00000265138.3|uniprotkb:A8K6T8|uniprotkb:Q9P2H1	psi-mi:hldd_yerpe(display_long)|uniprotkb:hldD(gene name)|psi-mi:hldD(display_short)|uniprotkb:htrM(gene name synonym)|uniprotkb:rfaD(gene name synonym)|uniprotkb:ADP-L-glycero-beta-D-manno-heptose-6-epimerase(gene name synonym)|uniprotkb:YPO0058(locus name)|uniprotkb:y0083(locus name)|uniprotkb:YP_0059(locus name)	psi-mi:arrd3_human(display_long)|uniprotkb:KIAA1376(gene name synonym)|uniprotkb:TBP-2-like inducible membrane protein(gene name synonym)|uniprotkb:ARRDC3(gene name)|psi-mi:ARRDC3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875689|imex:IM-13779-8309	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0008712""(ADP-glyceromanno-heptose 6-epimerase activity)|go:""GO:0009244""(lipopolysaccharide core region biosynthetic process)|go:""GO:0050661""(NADP binding)|go:""GO:0097171""(ADP-L-glycero-beta-D-manno-heptose biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR011912(ADP-L-glycero-D-manno-heptose-6-epimerase)|refseq:WP_002208983.1|refseq:YP_002345154.1|interpro:IPR036291|panther:PTHR43103(orthology-group)"	"ensembl:ENSG00000113369.9(gene)|ensembl:ENST00000265138.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|go:""GO:0031649""(heat generation)|go:""GO:0031651""(negative regulation of heat generation)|go:""GO:0031699""(beta-3 adrenergic receptor binding)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0043588""(skin development)|go:""GO:0051443""(positive regulation of ubiquitin-protein transferase activity)|go:""GO:0060613""(fat pad development)|go:""GO:0071878""(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway)|go:""GO:0090327""(negative regulation of locomotion involved in locomotory behavior)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR050357|mint:Q96B67|rcsb pdb:4N7H|rcsb pdb:4R7V|rcsb pdb:4R7X|refseq:NP_065852.1|panther:PTHR11188(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2knEr+z/cL1fefVFchNcvr7UE2Y632	rogid:XPgatMsOEeWbHJXTkQZsNXaWuNs9606	intact-crc:FFF194968713727E|rigid:sHa7UlQAbrmxWN8x8CRVqR4zU0s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15144	uniprotkb:Q8ZJN2	intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685.10|ensembl:ENSP00000327137.5	intact:EBI-2861608|uniprotkb:Q0WKN2	psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:tdh_yerpe(display_long)|uniprotkb:tdh(gene name)|psi-mi:tdh(display_short)|uniprotkb:YPO0060(locus name)|uniprotkb:y0080(locus name)|uniprotkb:YP_0061(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875710|imex:IM-13779-8308	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005722.1|refseq:NP_690601.1|ensembl:ENSG00000163466.16(gene)|ensembl:ENST00000295685.14(transcript)|ensembl:ENST00000315717.10(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0005925""(focal adhesion)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036195""(muscle cell projection membrane)|go:""GO:0043005""(neuron projection)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070358""(actin polymerization-dependent cell motility)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33197N|panther:PTHR12058(orthology-group)"	"interpro:IPR020843|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR004627(L-threonine 3-dehydrogenase)|refseq:WP_002208981.1|interpro:IPR050129|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008743""(L-threonine 3-dehydrogenase activity)|go:""GO:0019518""(L-threonine catabolic process to glycine)|interpro:IPR036291|refseq:YP_002345156.1|panther:PTHR43401(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:v5OozQTt614rvrBBoUavbAzjgZ49606	rogid:2WjdVfkVkq+pdNJ3zOcAd8D8Ywk632	intact-crc:99693836C570BAB9|rigid:f3iWFKCLZ6pnp/+3mbYpaMngo7s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5L9I8	uniprotkb:Q96B67	intact:EBI-2872190	intact:EBI-2875665|intact:EBI-28982382|ensembl:ENSP00000265138.3|uniprotkb:A8K6T8|uniprotkb:Q9P2H1	psi-mi:a0a3g5l9i8_yerpe(display_long)|uniprotkb:NCTC5923_03626(orf name)|uniprotkb:YP_0423(locus name)|uniprotkb:y0528(locus name)	psi-mi:arrd3_human(display_long)|uniprotkb:KIAA1376(gene name synonym)|uniprotkb:TBP-2-like inducible membrane protein(gene name synonym)|uniprotkb:ARRDC3(gene name)|psi-mi:ARRDC3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875671|imex:IM-13779-8310	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A0H2W1L0(uniprot-removed-ac)|refseq:WP_002218091.1	"ensembl:ENSG00000113369.9(gene)|ensembl:ENST00000265138.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|go:""GO:0031649""(heat generation)|go:""GO:0031651""(negative regulation of heat generation)|go:""GO:0031699""(beta-3 adrenergic receptor binding)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0043588""(skin development)|go:""GO:0051443""(positive regulation of ubiquitin-protein transferase activity)|go:""GO:0060613""(fat pad development)|go:""GO:0071878""(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway)|go:""GO:0090327""(negative regulation of locomotion involved in locomotory behavior)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR050357|mint:Q96B67|rcsb pdb:4N7H|rcsb pdb:4R7V|rcsb pdb:4R7X|refseq:NP_065852.1|panther:PTHR11188(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gEDKXDfEXKe5qFIrwqZlqPUb9I0632	rogid:XPgatMsOEeWbHJXTkQZsNXaWuNs9606	intact-crc:FA3691A66E96ABB6|rigid:c9jQ5OjkZHmjxDjIlY2dP5e6SVI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40617	uniprotkb:A0A0H2W6D0	intact:EBI-2875746|ensembl:ENSP00000349250.3|ensembl:ENSP00000379897.1|ensembl:ENSP00000379898.1|ensembl:ENSP00000379899.2|ensembl:ENSP00000385236.1|ensembl:ENSP00000498350.1|uniprotkb:A4D119|uniprotkb:P80418|uniprotkb:Q49AF5	intact:EBI-2862004|uniprotkb:Q74SF8|uniprotkb:Q0WCP0|uniprotkb:Q7CJH7|uniprotkb:A0A454XVI6|uniprotkb:A0A384KIW1	psi-mi:arl4a_human(display_long)|uniprotkb:ARL4A(gene name)|psi-mi:ARL4A(display_short)|uniprotkb:ARL4(gene name synonym)	psi-mi:a0a0h2w6d0_yerpe(display_long)|uniprotkb:YPO3028(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875743|imex:IM-13779-8314	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000122644.13(gene)|ensembl:ENST00000356797.7(transcript)|ensembl:ENST00000396662.5(transcript)|ensembl:ENST00000396663.2(transcript)|ensembl:ENST00000396664.2(transcript)|ensembl:ENST00000404894.1(transcript)|ensembl:ENST00000651779.1(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0050873""(brown fat cell differentiation)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR024156|interpro:IPR027417|refseq:NP_001032241.1|refseq:NP_001182325.1|refseq:NP_005729.1|refseq:NP_997625.1|panther:PTHR11711(orthology-group)"	"interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)|refseq:WP_002208523.1|interpro:IPR051551|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0009279""(cell outer membrane)|interpro:IPR036709|refseq:YP_002347948.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HeYXLZVghtF0zlvC7YW+RkNYMt09606	rogid:W2gvcG57x1Q5nQ5vtCMffIM1uB8632	intact-crc:DE38FC1DDD53BA8E|rigid:2eO7jJa/C6O0K3SR8rNOoQOwPoI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61158	uniprotkb:A0A2S9PFE9	intact:EBI-351428|uniprotkb:P32391|uniprotkb:Q53QM2|ensembl:ENSP00000263238.2|intact:EBI-21359005	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym)	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875736|imex:IM-13779-8311	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005712.1|ensembl:ENSG00000115091.12(gene)|ensembl:ENST00000263238.7(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0008356""(asymmetric cell division)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016344""(meiotic chromosome movement towards spindle pole)|go:""GO:0030027""(lamellipodium)|go:""GO:0033206""(meiotic cytokinesis)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051653""(spindle localization)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070358""(actin polymerization-dependent cell motility)|go:""GO:0071346""(cellular response to type II interferon)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N|panther:PTHR11937(orthology-group)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	intact-crc:6557D9C88C9F13E8|rigid:CMPb8eBcuRybOpYHXdNbqIzyX7Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15144	uniprotkb:Q7ARD3	intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685.10|ensembl:ENSP00000327137.5	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875717|imex:IM-13779-8312	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005722.1|refseq:NP_690601.1|ensembl:ENSG00000163466.16(gene)|ensembl:ENST00000295685.14(transcript)|ensembl:ENST00000315717.10(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005885""(Arp2/3 protein complex)|go:""GO:0005925""(focal adhesion)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036195""(muscle cell projection membrane)|go:""GO:0043005""(neuron projection)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070358""(actin polymerization-dependent cell motility)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|rcsb pdb:8P94|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33197N|panther:PTHR12058(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:v5OozQTt614rvrBBoUavbAzjgZ49606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:4E554FC41A2E1CEA|rigid:fxhONZ4/3lUO+PzLCJi4udD0Xqg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H9F9	uniprotkb:Q8ZBG8	intact:EBI-769418|uniprotkb:Q86WF7|uniprotkb:Q8IUY5|uniprotkb:Q8N724|uniprotkb:Q9BRN0|uniprotkb:Q9BVB7|ensembl:ENSP00000243903.4	intact:EBI-2875727|uniprotkb:Q0WBK1	psi-mi:arp5_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-16(gene name synonym)|uniprotkb:ACTR5(gene name)|psi-mi:ACTR5(display_short)|uniprotkb:ARP5(gene name synonym)	psi-mi:otc_yerpe(display_long)|uniprotkb:argI(gene name)|psi-mi:argI(display_short)|uniprotkb:YPO3446(locus name)|uniprotkb:y0740(locus name)|uniprotkb:YP_0638(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875724|imex:IM-13779-8313	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079131.3|ensembl:ENSG00000101442.10(gene)|ensembl:ENST00000243903.6(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006282""(regulation of DNA repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0031011""(Ino80 complex)|go:""GO:0033044""(regulation of chromosome organization)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060382""(regulation of DNA strand elongation)|go:""GO:0070914""(UV-damage excision repair)|go:""GO:1904507""(positive regulation of telomere maintenance in response to DNA damage)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:Q9H9F9|rcsb pdb:6HTS|rcsb pdb:7ZI4|reactome:R-HSA-5689603|reactome:R-HSA-5696394|dip:DIP-34297N|panther:PTHR11937(orthology-group)"	"go:""GO:0004585""(ornithine carbamoyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0016597""(amino acid binding)|go:""GO:0019240""(citrulline biosynthetic process)|go:""GO:0042450""(L-arginine biosynthetic process via ornithine)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR002292(Ornithine carbamoyltransferase)|interpro:IPR024904|refseq:WP_002209302.1|refseq:YP_002348337.1|interpro:IPR036901|panther:PTHR45753(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/26	rogid:ewlnWvZMDIX84KfZ6XIXXm9NBVI9606	rogid:RI2o13rUPlr21gYMwkl4rPGzxpg632	intact-crc:2B7FFEF1C38A9579|rigid:ICMxkhhbFQlBFRj1gYHsRTB1Z0U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q68CP9	uniprotkb:P68590	intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044.6	intact:EBI-2845098|uniprotkb:Q00929	psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym)	psi-mi:yopr_yerpe(display_long)|uniprotkb:yscH(gene name)|psi-mi:yscH(display_short)|uniprotkb:lcrP(gene name synonym)|uniprotkb:Yersinia outer protein R(gene name synonym)|uniprotkb:Yersinia secretion protein H(gene name synonym)|uniprotkb:yopR(gene name synonym)|uniprotkb:YPCD1.57(locus name)|uniprotkb:YP_pCD26(locus name)|uniprotkb:y0024(locus name)|uniprotkb:y5021(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875764|imex:IM-13779-8318	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000189079.18(gene)|ensembl:ENST00000334344.11(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006337""(nucleosome disassembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|interpro:IPR003150(DNA-binding RFX)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0042592""(homeostatic process)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0048568""(embryonic organ development)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|interpro:IPR052406|mint:Q68CP9|rcsb pdb:7VDV|rcsb pdb:7Y8R|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_001334768.1|refseq:NP_689854.2|dip:DIP-33391N|efo:""Orphanet:1465"""	"interpro:IPR013349(Type III secretion system effector YopR)|refseq:NP_395191.1|refseq:NP_857725.1|refseq:NP_857920.1|go:""GO:0005576""(extracellular region)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|rcsb pdb:1Z21|refseq:WP_002212915.1|mint:P68590|interpro:IPR041814"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606	rogid:vLBOGgil8yDmtkZgVzl8ti6IGok632	intact-crc:CDA2EE5CEED492B2|rigid:Xx54GI62p8wWsJxCLHZ6j1RjbfA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14865	uniprotkb:Q8CKI8	intact:EBI-1210388|uniprotkb:B4DLB3|uniprotkb:Q05DG6|uniprotkb:Q32Q59|uniprotkb:Q6NZ42|uniprotkb:Q5VST4|uniprotkb:Q7Z3M4|uniprotkb:Q8N421|uniprotkb:Q9H786|ensembl:ENSP00000279873.7	intact:EBI-2855532	psi-mi:ari5b_human(display_long)|uniprotkb:ARID5B(gene name)|psi-mi:ARID5B(display_short)|uniprotkb:DESRT(gene name synonym)|uniprotkb:MRF2(gene name synonym)|uniprotkb:MRF1-like protein(gene name synonym)|uniprotkb:Modulator recognition factor 2(gene name synonym)	psi-mi:q8cki8_yerpe(display_long)|uniprotkb:NCTC5923_02392(orf name)|uniprotkb:y3427(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875771|imex:IM-13779-8316	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115575.1|refseq:NP_001231567.1|ensembl:ENSG00000150347.17(gene)|ensembl:ENST00000279873.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0001822""(kidney development)|go:""GO:0001889""(liver development)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008584""(male gonad development)|go:""GO:0008585""(female gonad development)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010761""(fibroblast migration)|go:""GO:0030325""(adrenal gland development)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048468""(cell development)|go:""GO:0048644""(muscle organ morphogenesis)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060021""(roof of mouth development)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060612""(adipose tissue development)|go:""GO:0060613""(fat pad development)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR030408|interpro:IPR036431|interpro:IPR051232|mint:Q14865|rcsb pdb:1IG6|rcsb pdb:2OEH|reactome:R-HSA-3214842|panther:PTHR13964(orthology-group)"	refseq:WP_002213742.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:B6FNUWNl796yE+jX/0cAknrAkuo9606	rogid:kFpagl9Qd6b6ImFRX9++a7dnIjA632	intact-crc:C2BB06D8E8965DDE|rigid:ZaN3q0N7TdRxh2MeGwvNLIRD3TA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZN5	uniprotkb:Q8D0D4	intact:EBI-821440|uniprotkb:O15086|uniprotkb:Q6P526|ensembl:ENSP00000380942.2	intact:EBI-2847212	psi-mi:arhgc_human(display_long)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)	psi-mi:q8d0d4_yerpe(display_long)|uniprotkb:hmsH(gene name)|psi-mi:hmsH(display_short)|uniprotkb:y2359(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875785|imex:IM-13779-8319	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001185594.1|refseq:NP_056128.1|refseq:XP_011541022.1|refseq:XP_016872910.1|refseq:NP_001288013.1|dip:DIP-37887N|ensembl:ENSG00000196914.9(gene)|ensembl:ENST00000397843.7(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016020""(membrane)|rcsb pdb:2OS6|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037801|interpro:IPR037884|interpro:IPR041020|interpro:IPR044926|mint:Q9NZN5|rcsb pdb:1TXD|rcsb pdb:1X86|rcsb pdb:2OMJ|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|panther:PTHR45872(orthology-group)"	"interpro:IPR023870|interpro:IPR011990(Tetratricopeptide-like helical)|go:""GO:1901515""(poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity)|interpro:IPR049003"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606	rogid:oBs/IRM9/gKecuXNw9IoCZLu4Vw632	intact-crc:6D69F09E983BD865|rigid:Xc848vjr2PTCZs7pmS8lWroGu/M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GZL1	uniprotkb:O95154	intact:EBI-2854458|uniprotkb:Q74PS2|uniprotkb:Q0WB90|uniprotkb:A0A5P8YJZ1|uniprotkb:Q7CL96|uniprotkb:A0A384KMD8	intact:EBI-748869|uniprotkb:Q86SR4|uniprotkb:Q8IVN6|uniprotkb:Q8N5V6|uniprotkb:Q8TAX1|uniprotkb:Q9NUC3|ensembl:ENSP00000355377.4	psi-mi:a0a2u2gzl1_yerpe(display_long)|uniprotkb:pog(gene name)|psi-mi:pog(display_short)|uniprotkb:ssp(gene name synonym)|uniprotkb:sspA(gene name synonym)|uniprotkb:YPO3561(locus name)	psi-mi:ark73_human(display_long)|uniprotkb:AFB1 aldehyde reductase 2(gene name synonym)|uniprotkb:AKR7A3(gene name)|psi-mi:AKR7A3(display_short)|uniprotkb:AFAR2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875757|imex:IM-13779-8315	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR050983|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|rcsb pdb:1YY7|refseq:WP_002210135.1|interpro:IPR034341|interpro:IPR040079|interpro:IPR036249|interpro:IPR036282|refseq:YP_002348448.1|interpro:IPR034342	"refseq:NP_036199.2|ensembl:ENSG00000162482.5(gene)|ensembl:ENST00000361640.5(transcript)|go:""GO:0004033""(""aldo-keto reductase (NADPH) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006081""(aldehyde metabolic process)|go:""GO:0009055""(electron transfer activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR023210|interpro:IPR036812|interpro:IPR050523|mint:O95154|rcsb pdb:2CLP|reactome:R-HSA-5423646|panther:PTHR43625(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9smmAt4ZQb55TC9gx1z1tyl4bTI632	rogid:AaO++YDKdbqFs5RYgKtp2mcMrLI9606	intact-crc:8F54427F437CAB01|rigid:pvZod4sOHWNBJZYI9hdQTbCHc6I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YFN7	uniprotkb:Q4LE39	intact:EBI-2848958	intact:EBI-2680990|uniprotkb:Q86UX1|uniprotkb:Q5T2C5|uniprotkb:Q9NZB6|uniprotkb:Q9NYU3|uniprotkb:Q5T2C6|uniprotkb:Q5T2C3|uniprotkb:A1L465|uniprotkb:Q5HY99|uniprotkb:Q9NZG4|uniprotkb:Q86WR4|uniprotkb:Q9UF62|uniprotkb:Q9P2W4|uniprotkb:Q9H915|uniprotkb:Q5T2C2|uniprotkb:Q6P600|uniprotkb:Q3MHV4|uniprotkb:Q5T2C4|uniprotkb:Q9Y6E1|ensembl:ENSP00000264183.3|ensembl:ENSP00000355562.2	psi-mi:a0a5p8yfn7_yerpe(display_long)|uniprotkb:hrpA(gene name)|psi-mi:hrpA(display_short)|uniprotkb:NCTC5923_02603(orf name)|uniprotkb:YP_2109(locus name)|uniprotkb:y2011(locus name)	psi-mi:ari4b_human(display_long)|uniprotkb:BRCAA1(gene name synonym)|uniprotkb:RBBP1L1(gene name synonym)|uniprotkb:RBP1L1(gene name synonym)|uniprotkb:SAP180(gene name synonym)|uniprotkb:180 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Breast cancer-associated antigen BRCAA1(gene name synonym)|uniprotkb:Histone deacetylase complex subunit SAP180(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 1-like 1(gene name synonym)|uniprotkb:ARID4B(gene name)|psi-mi:ARID4B(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875778|imex:IM-13779-8317	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007502(Helicase-associated region)|interpro:IPR010222(RNA helicase, ATP-dependent DEAH box, HrpA type)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR024590|interpro:IPR027417|uniprotkb:A0A6B3T5A4(uniprot-removed-ac)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR048333|refseq:WP_002211005.1"	"refseq:XP_011542514.1|refseq:NP_001193723.1|refseq:NP_057458.4|refseq:NP_112739.2|ensembl:ENSG00000054267.22(gene)|ensembl:ENST00000264183.9(transcript)|ensembl:ENST00000366603.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070822""(Sin3-type complex)|go:""GO:0071514""(genomic imprinting)|go:""GO:0097368""(establishment of Sertoli cell barrier)|go:""GO:1902455""(negative regulation of stem cell population maintenance)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR002999(Tudor)|interpro:IPR012603(RBB1NT)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR028853|interpro:IPR036431|interpro:IPR047474|interpro:IPR047476|interpro:IPR051232|mint:Q4LE39|rcsb pdb:7DM4|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|panther:PTHR13964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aLxVjye9aRvQwd2fQxeIYUCRG+w632	rogid:qvmc05fd/Hu9k0HLB3gRG4ndRp89606	intact-crc:A5A8CDED06F9350B|rigid:W39H4kO+vvgosotAimk9fRr2538	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NP61	uniprotkb:Q0WGQ5	intact:EBI-2875816|ensembl:ENSP00000263245.5|uniprotkb:Q9Y4V4|uniprotkb:Q9NUP5|uniprotkb:Q9NT10|uniprotkb:Q9Y4V3|uniprotkb:Q9BSC6|uniprotkb:Q9H9J0|uniprotkb:E9PB03	intact:EBI-2853517|uniprotkb:Q74VA6|uniprotkb:Q7CHR0	psi-mi:arfg3_human(display_long)|uniprotkb:ARFGAP3(gene name)|psi-mi:ARFGAP3(display_short)|uniprotkb:ARFGAP1(gene name synonym)	psi-mi:q0wgq5_yerpe(display_long)|uniprotkb:YPO1517(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875813|imex:IM-13779-8321	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000242247.11(gene)|ensembl:ENST00000263245.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009306""(protein secretion)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0048205""(COPI coating of Golgi vesicle)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|mint:Q9NP61|rcsb pdb:2CRW|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_001135765.1|refseq:NP_055385.3|panther:PTHR45686(orthology-group)"	"interpro:IPR050555|interpro:IPR025997|interpro:IPR028082|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002346533.1|panther:PTHR30036(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1868s5elsn/sX/f8if3lmbLxKxg9606	rogid:qnuiW6B7FZ3gckfa7i2/HzKZAI8632	intact-crc:648959657B691CB2|rigid:Ad3HhyaFvRTKUODAsJ48etBTqes	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYS8	uniprotkb:P84077	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102.5|ensembl:ENSP00000514653.1|ensembl:ENSP00000514654.1|ensembl:ENSP00000514657.1	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875830|imex:IM-13779-8322	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	"panther:PTHR11711(orthology-group)|efo:""Orphanet:98892""|ensembl:ENSG00000143761.17(gene)|ensembl:ENST00000272102.10(transcript)|ensembl:ENST00000470558.5(transcript)|ensembl:ENST00000478336.5(transcript)|ensembl:ENST00000478424.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0002090""(regulation of receptor internalization)|go:""GO:0003723""(RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006878""(intracellular copper ion homeostasis)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030017""(sarcomere)|go:""GO:0031252""(cell leading edge)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0043005""(neuron projection)|go:""GO:0060292""(long-term synaptic depression)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097061""(dendritic spine organization)|go:""GO:0098586""(cellular response to virus)|go:""GO:1990386""(mitotic cleavage furrow ingression)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR024156|interpro:IPR027417|interpro:IPR045872|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7DN8|rcsb pdb:7DN9|rcsb pdb:7MGE|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9U|rcsb pdb:8D9W|rcsb pdb:8SDW|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505|reactome:R-HSA-9845576|refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	rogid:zray9asm6VonxpuJpv0dRBspPt89606	intact-crc:2A0031C23CC7D9EC|rigid:UbqUiQxPJ/tt0tYwF+ZMv9pqHZc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5LBG9	uniprotkb:Q9NZN5	intact:EBI-2843337|uniprotkb:Q7ARE7|uniprotkb:Q7BT22|uniprotkb:A0A1U8QL38|uniprotkb:O68742|uniprotkb:Q65AP5|uniprotkb:A0A2S9PDV0	intact:EBI-821440|uniprotkb:O15086|uniprotkb:Q6P526|ensembl:ENSP00000380942.2	psi-mi:a0a3g5lbg9_yerpe(display_long)|uniprotkb:YPMT1.25c(locus name)	psi-mi:arhgc_human(display_long)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875792|imex:IM-13779-8324	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395361.1|refseq:YP_093902.1|refseq:NP_857661.1|refseq:WP_002211788.1	"refseq:NP_001185594.1|refseq:NP_056128.1|refseq:XP_011541022.1|refseq:XP_016872910.1|refseq:NP_001288013.1|dip:DIP-37887N|ensembl:ENSG00000196914.9(gene)|ensembl:ENST00000397843.7(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0016020""(membrane)|rcsb pdb:2OS6|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037801|interpro:IPR037884|interpro:IPR041020|interpro:IPR044926|mint:Q9NZN5|rcsb pdb:1TXD|rcsb pdb:1X86|rcsb pdb:2OMJ|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|panther:PTHR45872(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:b42FykicLMYhKQ/f+NviSJexojE632	rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606	intact-crc:ED77885090FE981F|rigid:uoTuCJbuq7qIfc22Ui3rv+mmMhU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92888	uniprotkb:A0A2S9PIA6	intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532.3	intact:EBI-2842908|uniprotkb:Q74VK3|uniprotkb:Q7CHE2|uniprotkb:A0A5P8YDR0|uniprotkb:A0A0H2W4I9	psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym)	psi-mi:a0a2s9pia6_yerpe(display_long)|uniprotkb:YPO1289(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875799|imex:IM-13779-8320	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|panther:PTHR45872(orthology-group)|ensembl:ENSG00000076928.20(gene)|ensembl:ENST00000354532.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|interpro:IPR044926|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106"	"interpro:IPR011234(Fumarylacetoacetase, C-terminal-related)|refseq:WP_002208808.1|go:""GO:0003824""(catalytic activity)|go:""GO:0044281""(small molecule metabolic process)|interpro:IPR036663|refseq:YP_002346315.1|interpro:IPR051121"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606	rogid:3/IrNkmiHMcBViQNlB32br606NM632	intact-crc:837D1CB4277A2BC6|rigid:HTH/KsbImiAYEfGxwwhuZUJ43BI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P58543	uniprotkb:Q9NWB6	intact:EBI-2847390|uniprotkb:Q0WER7	intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059.3	psi-mi:arab_yerpe(display_long)|uniprotkb:araB(gene name)|psi-mi:araB(display_short)|uniprotkb:YPO2254(locus name)|uniprotkb:y2095(locus name)|uniprotkb:YP_2050(locus name)	psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875806|imex:IM-13779-8323	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018485|interpro:IPR005929(L-ribulokinase)|interpro:IPR043129|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008741""(ribulokinase activity)|go:""GO:0019150""(D-ribulokinase activity)|go:""GO:0019321""(pentose metabolic process)|go:""GO:0019569""(L-arabinose catabolic process to xylulose 5-phosphate)|refseq:YP_002347221.1|panther:PTHR43435(orthology-group)"	"refseq:NP_060481.3|ensembl:ENSG00000134884.15(gene)|ensembl:ENST00000400198.8(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0045296""(cadherin binding)|interpro:IPR033371|mint:Q9NWB6|panther:PTHR31711(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hejpPk7Q+tUU+cmG5v4jTehB47I632	rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606	intact-crc:0587D377CE1B99C8|rigid:idZNmrLbIKFekY4arMaQsmpRx3g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZU8	uniprotkb:P36406	intact:EBI-2840266	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524.9	psi-mi:q8czu8_yerpe(display_long)|uniprotkb:y3343(locus name)	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875844|imex:IM-13779-8327	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426"	"refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|ensembl:ENSG00000113595.15(gene)|ensembl:ENST00000231524.14(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019003""(GDP binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR024156|interpro:IPR027370|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|refseq:XP_016864933.1|panther:PTHR11711(orthology-group)|ensembl:ENSP00000231524.9|ensembl:ENST00000274327.11|ensembl:ENSP00000274327.7|ensembl:ENST00000381018.7|ensembl:ENSP00000370406.3"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E3RKB0jl/TdUsvcE+cnxsTkxh/k632	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	intact-crc:C3C78278D5D15A0D|rigid:gOxPWDcnqb8dX4MP53qxyZaPvPI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15514	uniprotkb:Q8CZM8	intact:EBI-953674|uniprotkb:Q5U026|ensembl:ENSP00000379097.3	intact:EBI-2848309	psi-mi:areg_human(display_long)|uniprotkb:Colorectum cell-derived growth factor(gene name synonym)|uniprotkb:AREG(gene name)|psi-mi:AREG(display_short)|uniprotkb:SDGF(gene name synonym)|uniprotkb:AREGB(gene name synonym)	psi-mi:q8czm8_yerpe(display_long)|uniprotkb:ptsA(gene name)|psi-mi:ptsA(display_short)|uniprotkb:y3776(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875837|imex:IM-13779-8325	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001648.1|dip:DIP-5766N|ensembl:ENSG00000109321.11(gene)|ensembl:ENST00000395748.8(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008083""(growth factor activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009986""(cell surface)|go:""GO:0010838""(positive regulation of keratinocyte proliferation)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0030297""(transmembrane receptor protein tyrosine kinase activator activity)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031175""(neuron projection development)|go:""GO:0032355""(response to estradiol)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0038134""(ERBB2-EGFR signaling pathway)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0051591""(response to cAMP)|go:""GO:0060598""(dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis)|go:""GO:0060744""(mammary gland branching involved in thelarche)|go:""GO:0060749""(mammary gland alveolus development)|go:""GO:0060750""(epithelial cell proliferation involved in mammary gland duct elongation)|interpro:IPR000742(EGF-like, type 3)|mint:P15514|rcsb pdb:2RNL|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-204005|reactome:R-HSA-212718|reactome:R-HSA-2219530|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-5694530|reactome:R-HSA-6811558|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9009391|reactome:R-HSA-9634638|reactome:R-HSA-9818030|panther:PTHR10740(orthology-group)"	"interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR018274|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR023151|interpro:IPR006318(Phosphoenolpyruvate-protein phosphotransferase)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR008731(Phosphotransferase system, PEP-utilising enzyme, N-terminal)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|go:""GO:0005737""(cytoplasm)|go:""GO:0008965""(phosphoenolpyruvate-protein phosphotransferase activity)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR040442|interpro:IPR035895|interpro:IPR036618|interpro:IPR036637|interpro:IPR050499"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qMTcDyIu2SQInZtwa5znbOrq6/c9606	rogid:yFrXLYA0rYHKZA16/O8hjY0IDfU632	intact-crc:FC77C84ED8910BF0|rigid:Pe4NxBMyPAjo7A2emAoTebI7DrM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P36406	uniprotkb:A0A6B3VFC8	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524.9	intact:EBI-2846593	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:a0a6b3vfc8_yerpe(display_long)|uniprotkb:NCTC5923_02253(orf name)|uniprotkb:y3286(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875851|imex:IM-13779-8328	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|ensembl:ENSG00000113595.15(gene)|ensembl:ENST00000231524.14(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019003""(GDP binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR024156|interpro:IPR027370|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|refseq:XP_016864933.1|panther:PTHR11711(orthology-group)|ensembl:ENSP00000231524.9|ensembl:ENST00000274327.11|ensembl:ENSP00000274327.7|ensembl:ENST00000381018.7|ensembl:ENSP00000370406.3"	uniprotkb:A0A6B3T013(uniprot-removed-ac)|refseq:WP_002209943.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:PLYBbO4aavg3f5tPrVCaWuDtPVg632	intact-crc:904A53C605F79F18|rigid:4SJ3b24OlvsdRaEBHc8CXRHtWlE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BEU0	uniprotkb:P36406	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524.9	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875858|imex:IM-13779-8326	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	"refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|ensembl:ENSG00000113595.15(gene)|ensembl:ENST00000231524.14(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019003""(GDP binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR024156|interpro:IPR027370|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|refseq:XP_016864933.1|panther:PTHR11711(orthology-group)|ensembl:ENSP00000231524.9|ensembl:ENST00000274327.11|ensembl:ENSP00000274327.7|ensembl:ENST00000381018.7|ensembl:ENSP00000370406.3"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	intact-crc:6B0EF869DE634406|rigid:bcWNbLf8Wdnk2CB5lAUc0gSZQ3Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIY3	uniprotkb:P35626	intact:EBI-2845647|uniprotkb:Q0WJV9	intact:EBI-2875868|ensembl:ENSP00000317578.4|uniprotkb:Q9UGW9	psi-mi:ch60_yerpe(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:mopA(gene name synonym)|uniprotkb:YPO0351(locus name)|uniprotkb:YP_0506(locus name)|uniprotkb:y0609(locus name)	psi-mi:arbk2_human(display_long)|uniprotkb:GRK3(gene name)|psi-mi:GRK3(display_short)|uniprotkb:ADRBK2(gene name synonym)|uniprotkb:BARK2(gene name synonym)|uniprotkb:Beta-adrenergic receptor kinase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875865|imex:IM-13779-8329	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|go:""GO:0005524""(ATP binding)|go:""GO:0009408""(response to heat)|go:""GO:0016853""(isomerase activity)|go:""GO:0042026""(protein refolding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1990220""(GroEL-GroES complex)|refseq:WP_002209128.1|interpro:IPR027410|refseq:YP_002345429.1|panther:PTHR45633(orthology-group)"	"ensembl:ENSG00000100077.16(gene)|ensembl:ENST00000324198.11(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0002029""(desensitization of G protein-coupled receptor signaling pathway)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004703""(G protein-coupled receptor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0031623""(receptor internalization)|go:""GO:0042995""(cell projection)|go:""GO:0047696""(beta-adrenergic receptor kinase activity)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|interpro:IPR044926|reactome:R-HSA-418555|reactome:R-HSA-8856825|refseq:NP_005151.2|panther:PTHR24355(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ns3NkyImUYTNcqMXDVXNh0E5DTY632	rogid:IXh7IeKOJ35sBT4TzFHPNB1xhnE9606	intact-crc:B948DDBD74283076|rigid:be1rIo3ls+y70+XoLwCuSRATNYk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D092	uniprotkb:P02649	intact:EBI-2845361	intact:EBI-1222467|uniprotkb:C0JYY5|uniprotkb:Q9P2S4|uniprotkb:B2RC15|ensembl:ENSP00000252486.3	psi-mi:q8d092_yerpe(display_long)|uniprotkb:fcuA(gene name)|psi-mi:fcuA(display_short)|uniprotkb:y2556(locus name)	psi-mi:apoe_human(display_long)|uniprotkb:APOE(gene name)|psi-mi:APOE(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875884|imex:IM-13779-8330	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR010105(TonB-dependent siderophore receptor)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426"	"efo:""Orphanet:158029""|efo:""Orphanet:329481""|efo:""Orphanet:412""|ensembl:ENSG00000130203.10(gene)|ensembl:ENST00000252486.9(transcript)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0002021""(response to dietary excess)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005319""(lipid transporter activity)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006641""(triglyceride metabolic process)|go:""GO:0006707""(cholesterol catabolic process)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007271""(synaptic transmission, cholinergic)|go:""GO:0007616""(long-term memory)|go:""GO:0008201""(heparin binding)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008289""(lipid binding)|go:""GO:0010467""(gene expression)|go:""GO:0010544""(negative regulation of platelet activation)|go:""GO:0010596""(negative regulation of endothelial cell migration)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0010877""(lipid transport involved in lipid storage)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0015909""(long-chain fatty acid transport)|go:""GO:0016020""(membrane)|go:""GO:0016209""(antioxidant activity)|go:""GO:0017038""(protein import)|go:""GO:0019068""(virion assembly)|go:""GO:0019899""(enzyme binding)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0030425""(dendrite)|go:""GO:0030516""(regulation of axon extension)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031175""(neuron projection development)|go:""GO:0032438""(melanosome organization)|go:""GO:0032489""(regulation of Cdc42 protein signal transduction)|go:""GO:0032805""(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0033700""(phospholipid efflux)|go:""GO:0034360""(chylomicron remnant)|go:""GO:0034361""(very-low-density lipoprotein particle)|go:""GO:0034362""(low-density lipoprotein particle)|go:""GO:0034363""(intermediate-density lipoprotein particle)|go:""GO:0034364""(high-density lipoprotein particle)|go:""GO:0034365""(discoidal high-density lipoprotein particle)|go:""GO:0034372""(very-low-density lipoprotein particle remodeling)|go:""GO:0034374""(low-density lipoprotein particle remodeling)|go:""GO:0034375""(high-density lipoprotein particle remodeling)|go:""GO:0034380""(high-density lipoprotein particle assembly)|go:""GO:0034382""(chylomicron remnant clearance)|go:""GO:0034384""(high-density lipoprotein particle clearance)|go:""GO:0034447""(very-low-density lipoprotein particle clearance)|go:""GO:0035641""(locomotory exploration behavior)|go:""GO:0038060""(nitric oxide-cGMP-mediated signaling)|go:""GO:0042158""(lipoprotein biosynthetic process)|go:""GO:0042159""(lipoprotein catabolic process)|go:""GO:0042311""(vasodilation)|go:""GO:0042470""(melanosome)|go:""GO:0042627""(chylomicron)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0042982""(amyloid precursor protein metabolic process)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043083""(synaptic cleft)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0043691""(reverse cholesterol transport)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045088""(regulation of innate immune response)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045541""(negative regulation of cholesterol biosynthetic process)|go:""GO:0045807""(positive regulation of endocytosis)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046889""(positive regulation of lipid biosynthetic process)|go:""GO:0046907""(intracellular transport)|go:""GO:0046911""(metal chelating activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0048168""(regulation of neuronal synaptic plasticity)|go:""GO:0048662""(negative regulation of smooth muscle cell proliferation)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0050709""(negative regulation of protein secretion)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051044""(positive regulation of membrane protein ectodomain proteolysis)|go:""GO:0051246""(regulation of protein metabolic process)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0051651""(maintenance of location in cell)|go:""GO:0055089""(fatty acid homeostasis)|go:""GO:0055090""(acylglycerol homeostasis)|go:""GO:0060228""(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:""GO:0060999""(positive regulation of dendritic spine development)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0061771""(response to caloric restriction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070326""(very-low-density lipoprotein particle receptor binding)|go:""GO:0070328""(triglyceride homeostasis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071402""(cellular response to lipoprotein particle stimulus)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0071813""(lipoprotein particle binding)|go:""GO:0071830""(triglyceride-rich lipoprotein particle clearance)|go:""GO:0071831""(intermediate-density lipoprotein particle clearance)|go:""GO:0072562""(blood microparticle)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0090181""(regulation of cholesterol metabolic process)|go:""GO:0090205""(positive regulation of cholesterol metabolic process)|go:""GO:0090209""(negative regulation of triglyceride metabolic process)|go:""GO:0097113""(AMPA glutamate receptor clustering)|go:""GO:0097114""(NMDA glutamate receptor clustering)|go:""GO:0097487""(multivesicular body, internal vesicle)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0120020""(cholesterol transfer activity)|go:""GO:0140077""(positive regulation of lipoprotein transport)|go:""GO:1900221""(regulation of amyloid-beta clearance)|go:""GO:1900223""(positive regulation of amyloid-beta clearance)|go:""GO:1900272""(negative regulation of long-term synaptic potentiation)|go:""GO:1902430""(negative regulation of amyloid-beta formation)|go:""GO:1902952""(positive regulation of dendritic spine maintenance)|go:""GO:1902991""(regulation of amyloid precursor protein catabolic process)|go:""GO:1902995""(positive regulation of phospholipid efflux)|go:""GO:1903002""(positive regulation of lipid transport across blood-brain barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1905890""(regulation of cellular response to very-low-density lipoprotein particle stimulus)|go:""GO:1905906""(regulation of amyloid fibril formation)|go:""GO:1905907""(negative regulation of amyloid fibril formation)|go:""GO:1905908""(positive regulation of amyloid fibril formation)|go:""GO:1905920""(positive regulation of CoA-transferase activity)|go:""GO:1990777""(lipoprotein particle)|go:""GO:2000822""(regulation of behavioral fear response)|interpro:IPR000074(Apolipoprotein A1/A4/E)|interpro:IPR050163|mint:P02649|rcsb pdb:1B68|rcsb pdb:1BZ4|rcsb pdb:1EA8|rcsb pdb:1GS9|rcsb pdb:1H7I|rcsb pdb:1LE2|rcsb pdb:1LE4|rcsb pdb:1LPE|rcsb pdb:1NFN|rcsb pdb:1NFO|rcsb pdb:1OEF|rcsb pdb:1OEG|rcsb pdb:1OR2|rcsb pdb:1OR3|rcsb pdb:2KC3|rcsb pdb:2KNY|rcsb pdb:2L7B|rcsb pdb:6IWB|rcsb pdb:6NCN|rcsb pdb:6NCO|rcsb pdb:7FCR|rcsb pdb:7FCS|rcsb pdb:7UVJ|rcsb pdb:8AX8|rcsb pdb:8AX9|rcsb pdb:8CDY|rcsb pdb:8CE0|rcsb pdb:8GRX|reactome:R-HSA-1251985|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-8864260|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964058|reactome:R-HSA-9029569|reactome:R-HSA-975634|reactome:R-HSA-977225|refseq:NP_000032.1|refseq:NP_001289617.1|refseq:NP_001289618.1|refseq:NP_001289619.1|refseq:NP_001289620.1|dip:DIP-1120N|panther:PTHR18976(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:7oNsiLRBKD+1PyrMueBNpf/zdLs632	rogid:vnCU03+HdGblqtALKeOTZRx5/3E9606	intact-crc:04502A0F06BCEBD4|rigid:kslLx9WcW83eYXqiMAVa/Mg21Ws	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35414	uniprotkb:Q0WDE1	intact:EBI-2875891|ensembl:ENSP00000257254.3|ensembl:ENSP00000475344.1	intact:EBI-2848934|uniprotkb:Q74SY9|uniprotkb:Q8D0U7	psi-mi:apj_human(display_long)|uniprotkb:APLNR(gene name)|psi-mi:APLNR(display_short)|uniprotkb:AGTRL1(gene name synonym)|uniprotkb:APJ(gene name synonym)|uniprotkb:Angiotensin receptor-like 1(gene name synonym)|uniprotkb:G-protein coupled receptor APJ(gene name synonym)|uniprotkb:G-protein coupled receptor HG11(gene name synonym)	psi-mi:prmb_yerpe(display_long)|uniprotkb:prmB(gene name)|psi-mi:prmB(display_short)|uniprotkb:N5-glutamine methyltransferase PrmB(gene name synonym)|uniprotkb:YPO2750(locus name)|uniprotkb:YP_2413(locus name)|uniprotkb:y1584(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875895|imex:IM-13779-8331	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000134817.12(gene)|ensembl:ENST00000257254.3(transcript)|ensembl:ENST00000606794.2(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001568""(blood vessel development)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001944""(vasculature development)|go:""GO:0001947""(heart looping)|go:""GO:0003171""(atrioventricular valve development)|go:""GO:0003272""(endocardial cushion formation)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0007369""(gastrulation)|go:""GO:0007507""(heart development)|go:""GO:0007512""(adult heart development)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0035886""(vascular associated smooth muscle cell differentiation)|go:""GO:0035904""(aorta development)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0043951""(negative regulation of cAMP-mediated signaling)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0050878""(regulation of body fluid levels)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0060182""(apelin receptor activity)|go:""GO:0060183""(apelin receptor signaling pathway)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060841""(venous blood vessel development)|go:""GO:0060976""(coronary vasculature development)|go:""GO:1903589""(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:1903596""(regulation of gap junction assembly)|go:""GO:1904022""(positive regulation of G protein-coupled receptor internalization)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR003904(APJ receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR050119|mint:P35414|rcsb pdb:2LOT|rcsb pdb:2LOU|rcsb pdb:2LOV|rcsb pdb:2LOW|rcsb pdb:5VBL|rcsb pdb:6KNM|rcsb pdb:7SUS|rcsb pdb:7W0L|rcsb pdb:7W0M|rcsb pdb:7W0N|rcsb pdb:7W0O|rcsb pdb:7W0P|rcsb pdb:8XZF|rcsb pdb:8XZG|rcsb pdb:8XZH|rcsb pdb:8XZI|rcsb pdb:8XZJ|reactome:R-HSA-375276|reactome:R-HSA-418594|refseq:NP_005152.1|panther:PTHR24228(orthology-group)"	"interpro:IPR029063|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004556(Modification methylase HemK)|interpro:IPR017127(""Protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific"")|interpro:IPR007848(Methyltransferase small)|refseq:WP_002209710.1|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005829""(cytosol)|go:""GO:0032259""(methylation)|go:""GO:0036009""(protein-glutamine N-methyltransferase activity)|refseq:YP_002347697.1|panther:PTHR47806(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OaKR4qnsU9jANK+HB2qQ4TlanpQ9606	rogid:E0TcJR1cPqw7XzHhfs/tgH45UN8632	intact-crc:AF95A75D292E15C5|rigid:GpzA7odBSL0R/538fUEwELyJ2v8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCQ2	uniprotkb:Q66PJ3	intact:EBI-2850142|uniprotkb:Q0WCY7	intact:EBI-2683099|uniprotkb:Q9NR05|uniprotkb:Q4F966|uniprotkb:Q9P2R9|uniprotkb:Q96BI2|uniprotkb:Q504R8|uniprotkb:A4UCR8|uniprotkb:B3V0L0|uniprotkb:B3V0L1|ensembl:ENSP00000313422.7	psi-mi:pur4_yerpe(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:YPO2921(locus name)|uniprotkb:YP_2536(locus name)|uniprotkb:y1309(locus name)	psi-mi:ar6p4_human(display_long)|uniprotkb:HSP-975(gene name synonym)|uniprotkb:HSVI-binding protein(gene name synonym)|uniprotkb:SR-15(gene name synonym)|uniprotkb:SRp25(gene name synonym)|uniprotkb:Splicing factor SRrp37(gene name synonym)|uniprotkb:ARL6IP4(gene name)|psi-mi:ARL6IP4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875877|imex:IM-13779-8332	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR029062|refseq:WP_002211561.1|interpro:IPR040707|go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609|refseq:YP_002347851.1|panther:PTHR10099(orthology-group)"	"refseq:NP_001002251.2|refseq:NP_001002252.2|refseq:NP_001265307.1|refseq:NP_001265308.1|refseq:NP_001265309.1|refseq:NP_061164.3|refseq:NP_057722.3|ensembl:ENSG00000182196.14(gene)|ensembl:ENST00000315580.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|interpro:IPR019532|mint:Q66PJ3"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8JTbD5hWDWC5PK7sHtiOwqqdyHs632	rogid:29X57zmO6JmoS1Mqrid1Cd50as49606	intact-crc:D882505AB1278C21|rigid:ndeWyrTVULLE1Jg2g/F+mTipC4I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35414	uniprotkb:A0A2U2GXK0	intact:EBI-2875891|ensembl:ENSP00000257254.3|ensembl:ENSP00000475344.1	intact:EBI-2875905|uniprotkb:Q0WGZ8|uniprotkb:Q74VU7|uniprotkb:A0A5P8YHQ2|uniprotkb:A0A384KJE6|uniprotkb:Q7CHK6	psi-mi:apj_human(display_long)|uniprotkb:APLNR(gene name)|psi-mi:APLNR(display_short)|uniprotkb:AGTRL1(gene name synonym)|uniprotkb:APJ(gene name synonym)|uniprotkb:Angiotensin receptor-like 1(gene name synonym)|uniprotkb:G-protein coupled receptor APJ(gene name synonym)|uniprotkb:G-protein coupled receptor HG11(gene name synonym)	psi-mi:a0a2u2gxk0_yerpe(display_long)|uniprotkb:YPO1417(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875902|imex:IM-13779-8333	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000134817.12(gene)|ensembl:ENST00000257254.3(transcript)|ensembl:ENST00000606794.2(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001568""(blood vessel development)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001944""(vasculature development)|go:""GO:0001947""(heart looping)|go:""GO:0003171""(atrioventricular valve development)|go:""GO:0003272""(endocardial cushion formation)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0007369""(gastrulation)|go:""GO:0007507""(heart development)|go:""GO:0007512""(adult heart development)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0035886""(vascular associated smooth muscle cell differentiation)|go:""GO:0035904""(aorta development)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0043951""(negative regulation of cAMP-mediated signaling)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0050878""(regulation of body fluid levels)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0060182""(apelin receptor activity)|go:""GO:0060183""(apelin receptor signaling pathway)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060841""(venous blood vessel development)|go:""GO:0060976""(coronary vasculature development)|go:""GO:1903589""(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:1903596""(regulation of gap junction assembly)|go:""GO:1904022""(positive regulation of G protein-coupled receptor internalization)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR003904(APJ receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR050119|mint:P35414|rcsb pdb:2LOT|rcsb pdb:2LOU|rcsb pdb:2LOV|rcsb pdb:2LOW|rcsb pdb:5VBL|rcsb pdb:6KNM|rcsb pdb:7SUS|rcsb pdb:7W0L|rcsb pdb:7W0M|rcsb pdb:7W0N|rcsb pdb:7W0O|rcsb pdb:7W0P|rcsb pdb:8XZF|rcsb pdb:8XZG|rcsb pdb:8XZH|rcsb pdb:8XZI|rcsb pdb:8XZJ|reactome:R-HSA-375276|reactome:R-HSA-418594|refseq:NP_005152.1|panther:PTHR24228(orthology-group)"	"go:""GO:0003824""(catalytic activity)|go:""GO:0030151""(molybdenum ion binding)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR001041(Ferredoxin)|interpro:IPR005302(Molybdenum cofactor sulphurase, C-terminal)|interpro:IPR005303(MOSC, N-terminal beta barrel)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|refseq:WP_002211294.1|refseq:YP_002346440.1|interpro:IPR036010"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OaKR4qnsU9jANK+HB2qQ4TlanpQ9606	rogid:e1R/2q8JnmP1aeiu40dWMrijzOI632	intact-crc:0CBC1AC405E5072E|rigid:jgnouCdJqVgS144eNPAJAMR2MHE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q02410	uniprotkb:A0A2S9PLH1	intact:EBI-368690|uniprotkb:O14914|uniprotkb:O60570|uniprotkb:Q5VYR8|intact:EBI-8840163|intact:EBI-8840293|ensembl:ENSP00000265381.3	intact:EBI-2856592|uniprotkb:Q74X46|uniprotkb:Q7CKH1|uniprotkb:A0A0H2W2R5	psi-mi:apba1_human(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)	psi-mi:a0a2s9plh1_yerpe(display_long)|uniprotkb:YPO3468(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875941|imex:IM-13779-8336	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005252025.1|refseq:NP_001154.2|ensembl:ENSG00000107282.9(gene)|ensembl:ENST00000265381.7(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007155""(cell adhesion)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007399""(nervous system development)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008088""(axo-dendritic transport)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0014047""(glutamate secretion)|go:""GO:0014051""(gamma-aminobutyric acid secretion)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0043197""(dendritic spine)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048787""(presynaptic active zone membrane)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099171""(presynaptic modulation of chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR051230|mint:Q02410|rcsb pdb:1AQC|rcsb pdb:1U37|rcsb pdb:1U38|rcsb pdb:1U39|rcsb pdb:1U3B|rcsb pdb:1X11|rcsb pdb:1X45|rcsb pdb:1Y7N|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:XP_011516919.1|refseq:XP_016870159.1|panther:PTHR12345(orthology-group)"	"refseq:WP_002209281.1|interpro:IPR008397(Alginate lyase)|interpro:IPR008929(Chondroitin AC/alginate lyase)|go:""GO:0016829""(lyase activity)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348357.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606	rogid:XJauDb6vvXdcLKHXeXt+Js2URk8632	intact-crc:3AF41F36C50B731B|rigid:B/oyQO1NJmoPyVYwsg7a0YmRyIM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1B3	uniprotkb:Q96GX9	intact:EBI-2840595|uniprotkb:Q74XV1	intact:EBI-359248|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3|ensembl:ENSP00000379133.3	psi-mi:q8d1b3_yerpe(display_long)|uniprotkb:hpt(gene name)|psi-mi:hpt(display_short)|uniprotkb:y0778(locus name)|uniprotkb:YP_0277(locus name)	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875913|imex:IM-13779-8338	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR000836(Phosphoribosyltransferase)|go:""GO:0000166""(nucleotide binding)|go:""GO:0004422""(hypoxanthine phosphoribosyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006166""(purine ribonucleoside salvage)|go:""GO:0032264""(IMP salvage)|go:""GO:0046872""(metal ion binding)|go:""GO:0052657""(guanine phosphoribosyltransferase activity)|interpro:IPR029057|interpro:IPR050408"	"refseq:NP_057041.2|ensembl:ENSG00000149089.13(gene)|ensembl:ENST00000395787.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0019509""(L-methionine salvage from methylthioadenosine)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046570""(methylthioribulose 1-phosphate dehydratase activity)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|panther:PTHR10640(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hEatsWS41qw+itGzSZ3/6OZp1FA632	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	intact-crc:A25FAB61C035F704|rigid:CSATidrmQYG86ELEvj2B+Jt3KYw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WH72	uniprotkb:Q96GX9	intact:EBI-2850434|uniprotkb:Q74VP2|uniprotkb:A0A2S9PE74|uniprotkb:Q7CHH1|uniprotkb:A0A0H2W437	intact:EBI-359248|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3|ensembl:ENSP00000379133.3	psi-mi:q0wh72_yerpe(display_long)|uniprotkb:YPO1343(locus name)	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875920|imex:IM-13779-8334	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR002491(Periplasmic binding protein)|refseq:YP_002346366.1|interpro:IPR050902	"refseq:NP_057041.2|ensembl:ENSG00000149089.13(gene)|ensembl:ENST00000395787.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0019509""(L-methionine salvage from methylthioadenosine)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046570""(methylthioribulose 1-phosphate dehydratase activity)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|panther:PTHR10640(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mNlEz7MBUwvI3HEqPO5jS8aG5zo632	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	intact-crc:979D3409487AC718|rigid:fAm1g0dmpkcCf/AsP1Bok27trBM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96GX9	uniprotkb:A0A7Y8RC16	intact:EBI-359248|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3|ensembl:ENSP00000379133.3	intact:EBI-2843188|uniprotkb:Q74PV7|uniprotkb:A0A0H2W7X5|uniprotkb:Q7CG44|uniprotkb:Q0WJQ7|uniprotkb:A0A384KPQ0	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	psi-mi:a0a7y8rc16_yerpe(display_long)|uniprotkb:YPO0404(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875927|imex:IM-13779-8337	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057041.2|ensembl:ENSG00000149089.13(gene)|ensembl:ENST00000395787.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0019509""(L-methionine salvage from methylthioadenosine)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046570""(methylthioribulose 1-phosphate dehydratase activity)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|panther:PTHR10640(orthology-group)"	"interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR006327(Phosphotransferase system, fructose IIC component)|interpro:IPR013014(Phosphotransferase system, EIIC component, type 2)|go:""GO:0005351""(""carbohydrate:proton symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|refseq:YP_002345481.1|interpro:IPR050864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	rogid:SLkzxzvdatLCfveYdH0UaKifvHU632	intact-crc:CEA3548C275BB057|rigid:OzCjd0ts36QBvCQ9NfTdx+CsbkA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P69974	uniprotkb:Q99767	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	intact:EBI-81711|uniprotkb:O60571|ensembl:ENSP00000453144.1|ensembl:ENSP00000453293.1|ensembl:ENSP00000454171.1|ensembl:ENSP00000480384.1|ensembl:ENSP00000488107.1|ensembl:ENSP00000507394.1|uniprotkb:E9PGI4|uniprotkb:Q5XKC0	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	psi-mi:apba2_human(display_long)|uniprotkb:APBA2(gene name)|psi-mi:APBA2(display_short)|uniprotkb:MINT2(gene name synonym)|uniprotkb:X11L(gene name synonym)|uniprotkb:Neuron-specific X11L protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 2(gene name synonym)|uniprotkb:Adapter protein X11beta(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875934|imex:IM-13779-8335	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	"refseq:NP_001123886.1|refseq:NP_005494.2|refseq:XP_016877590.1|refseq:XP_016877591.1|refseq:XP_016877592.1|refseq:XP_016877593.1|refseq:XP_016877594.1|refseq:XP_016877595.1|refseq:XP_016877596.1|refseq:XP_016877597.1|refseq:XP_016877598.1|refseq:XP_016877599.1|refseq:XP_016877600.1|refseq:XP_016877601.1|refseq:XP_016877602.1|refseq:XP_016877603.1|ensembl:ENSG00000034053.15(gene)|ensembl:ENSG00000276495.4(gene)|ensembl:ENST00000558259.5(transcript)|ensembl:ENST00000558402.5(transcript)|ensembl:ENST00000561069.5(transcript)|ensembl:ENST00000620457.4(transcript)|ensembl:ENST00000631894.1(transcript)|ensembl:ENST00000683413.1(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007399""(nervous system development)|go:""GO:0007626""(locomotory behavior)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0015031""(protein transport)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098793""(presynapse)|go:""GO:0099171""(presynaptic modulation of chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR051230|mint:Q99767|reactome:R-HSA-6794361|panther:PTHR12345(orthology-group)|refseq:XP_016877604.1|refseq:XP_016877605.1|refseq:XP_016877606.1|refseq:XP_011519790.1|refseq:XP_011519791.1|refseq:XP_011519792.1|refseq:XP_011519793.1|refseq:XP_011519794.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/07	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	rogid:gO80zdSUhRm1hFaFBfeQyDCGh3w9606	intact-crc:83F973C4629D3D21|rigid:TorvHjE33Sc+E21Xwx5L2sy+rDs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63010	uniprotkb:Q8CLS7	intact:EBI-432924|ensembl:ENSP00000482315.1|uniprotkb:A6NJP3|uniprotkb:P21851|uniprotkb:Q96J19|intact:EBI-8011909|intact:MINT-8395045|uniprotkb:Q7Z451|intact:EBI-28970775	intact:EBI-2875969	psi-mi:ap2b1_human(display_long)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:q8cls7_yerpe(display_long)|uniprotkb:y0291(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875972|imex:IM-13779-8341	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000006125.18(gene)|ensembl:ENST00000621914.4(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0005048""(signal sequence binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030122""(AP-2 adaptor complex)|go:""GO:0030131""(clathrin adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0035904""(aorta development)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0060976""(coronary vasculature development)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|rcsb pdb:2IV8|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:P63010|rcsb pdb:1E42|rcsb pdb:2G30|rcsb pdb:2IV9|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:4UQI|rcsb pdb:5M5R|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6QH7|rcsb pdb:6URI|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|rcsb pdb:6YAI|rcsb pdb:7OG1|rcsb pdb:7OHO|rcsb pdb:7OM8|rcsb pdb:7Z5C|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|refseq:NP_001025177.1|refseq:NP_001273.1|refseq:XP_005257994.1|refseq:XP_005257995.1|refseq:XP_011522757.1|refseq:XP_016879773.1|refseq:XP_016879775.1|dip:DIP-33098N|panther:PTHR11134(orthology-group)"	interpro:IPR025326	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:Q5oFhdE1hcmqu7xLG3MteCu0Zcg9606	rogid:Hwpa+1i7TmVLCVxag1YETh57Kz0632	intact-crc:95F76EFA86411AD6|rigid:W2Nq8nV5GLWW85w6Afho/m9Cl/I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GUZ8	uniprotkb:O14617	intact:EBI-2858974|uniprotkb:Q74PU1|uniprotkb:A0A380PJ37|uniprotkb:Q0WJS3|uniprotkb:Q7CG32|uniprotkb:A0A384L519	intact:EBI-1051639|uniprotkb:O00202|uniprotkb:O75262|uniprotkb:Q59HF5|uniprotkb:Q96G11|uniprotkb:Q9H3C6|ensembl:ENSP00000344055.4	psi-mi:a0a2u2guz8_yerpe(display_long)|uniprotkb:YPO0388(locus name)	psi-mi:ap3d1_human(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:AP3D1(gene name)|psi-mi:AP3D1(display_short)|uniprotkb:PRO0039(orf name)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875955|imex:IM-13779-8340	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR019292|refseq:WP_002209167.1|refseq:YP_002345465.1	"efo:""Orphanet:664511""|dip:DIP-46793N|ensembl:ENSG00000065000.20(gene)|ensembl:ENST00000345016.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016182""(synaptic vesicle budding from endosome)|go:""GO:0016183""(synaptic vesicle coating)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0032438""(melanosome organization)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0043195""(terminal bouton)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046907""(intracellular transport)|go:""GO:0048007""(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0048499""(synaptic vesicle membrane organization)|go:""GO:0051138""(positive regulation of NK T cell differentiation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0098794""(postsynapse)|go:""GO:0098830""(presynaptic endosome)|go:""GO:0098943""(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140916""(zinc ion import into lysosome)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O14617|rcsb pdb:4AFI|refseq:NP_001248755.1|refseq:NP_003929.4|efo:""Orphanet:1000""|efo:""Orphanet:54""|panther:PTHR22781(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:KAzzgB6fVtKcGVFVzqcVYB96Yyk632	rogid:vw6bWz07cMYuwATlyDgx14oXzKY9606	intact-crc:938E2E25D0ED385E|rigid:WtQQS0m0VpRYbhrCYZYlkjxzZ2M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00203	uniprotkb:Q0WAW4	intact:EBI-1044383|uniprotkb:O00580|uniprotkb:Q7Z393|uniprotkb:Q9HD66|uniprotkb:E5RJ68|intact:EBI-10969499|ensembl:ENSP00000255194.7	intact:EBI-2845527|uniprotkb:Q74PP4|uniprotkb:A0A0H2W9X7|uniprotkb:Q7CL78|uniprotkb:A0A384L395	psi-mi:ap3b1_human(display_long)|uniprotkb:Adaptor protein complex AP-3 subunit beta-1(gene name synonym)|uniprotkb:Beta-3A-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta-1 large chain(gene name synonym)|uniprotkb:AP3B1(gene name)|psi-mi:AP3B1(display_short)|uniprotkb:ADTB3A(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta-1(gene name synonym)	psi-mi:q0waw4_yerpe(display_long)|uniprotkb:tldE(gene name synonym)|uniprotkb:pmbA(gene name)|psi-mi:pmbA(display_short)|uniprotkb:YPO3692(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875962|imex:IM-13779-8342	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:664500""|dip:DIP-24208N|ensembl:ENSG00000132842.16(gene)|ensembl:ENST00000255194.11(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003016""(respiratory system process)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006954""(inflammatory response)|go:""GO:0007040""(lysosome organization)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007338""(single fertilization)|go:""GO:0007596""(blood coagulation)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030131""(clathrin adaptor complex)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0030851""(granulocyte differentiation)|go:""GO:0032438""(melanosome organization)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0036211""(protein modification process)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046907""(intracellular transport)|go:""GO:0048007""(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0048872""(homeostasis of number of cells)|go:""GO:0051138""(positive regulation of NK T cell differentiation)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0060425""(lung morphogenesis)|go:""GO:0090152""(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:""GO:0098773""(skin epidermis development)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990742""(microvesicle)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|interpro:IPR029394|mint:O00203|reactome:R-HSA-432722|reactome:R-HSA-6802952|refseq:NP_001258698.1|refseq:NP_003655.3|panther:PTHR11134(orthology-group)"	"interpro:IPR035068|interpro:IPR002510(Peptidase U62, modulator of DNA gyrase)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|interpro:IPR036059|refseq:WP_002210100.1|interpro:IPR047657|refseq:YP_002348574.1|interpro:IPR045569|interpro:IPR045570|panther:PTHR43421(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+06UuQo62p9ALS7DiX+yKg7YRyg9606	rogid:1r1xtUqHzuYMk5OIsEkQSog3/FU632	intact-crc:EF9BAB6DEBDE8002|rigid:RGy50Ymw+EuFI51YGxsFasuGa3I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2T2	uniprotkb:Q8ZD36	intact:EBI-2371151|uniprotkb:Q5JQ12|uniprotkb:Q9H5L2|ensembl:ENSP00000347408.4|ensembl:ENSP00000361831.1	intact:EBI-2853182|uniprotkb:Q0WDD5|intact:EBI-2862751	psi-mi:ap3m1_human(display_long)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu-1(gene name synonym)|uniprotkb:AP3M1(gene name)|psi-mi:AP3M1(display_short)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:Mu3A-adaptin(gene name synonym)	psi-mi:mnmc_yerpe(display_long)|uniprotkb:mnmC(gene name)|psi-mi:mnmC(display_short)|uniprotkb:YPO2756(locus name)|uniprotkb:y1590(locus name)|uniprotkb:YP_2407(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875948|imex:IM-13779-8339	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001307192.1|refseq:NP_001307193.1|ensembl:ENSG00000185009.13(gene)|ensembl:ENST00000355264.9(transcript)|ensembl:ENST00000372745.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006897""(endocytosis)|go:""GO:0008089""(anterograde axonal transport)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030131""(clathrin adaptor complex)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0035654""(clathrin-coated vesicle cargo loading, AP-3-mediated)|go:""GO:0046907""(intracellular transport)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0098837""(postsynaptic recycling endosome)|go:""GO:0098884""(postsynaptic neurotransmitter receptor internalization)|go:""GO:1903232""(melanosome assembly)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR050431|mint:Q9Y2T2|reactome:R-HSA-390471|refseq:NP_036227.1|refseq:NP_996895.1|panther:PTHR10529(orthology-group)"	"interpro:IPR029063|interpro:IPR008471(Protein of unknown function DUF752)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR023032|interpro:IPR017610(tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal)|rcsb pdb:3PVC|rcsb pdb:3SGL|refseq:WP_002209716.1|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0004808""(""tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0016645""(oxidoreductase activity, acting on the CH-NH group of donors)|go:""GO:0032259""(methylation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR047785|interpro:IPR036188|refseq:YP_002347703.1|panther:PTHR13847(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VsXYkOxEite1RzT1YHCA6/U4gj09606	rogid:WUUEfp2U7AMQZl+RUxlKHTdbp3E632	intact-crc:7EB12D4CC676EEFB|rigid:9m8Gea8+CI6KCm87HkTSkK8R4zU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ZC68	uniprotkb:O75843	intact:EBI-2843867|uniprotkb:Q7CI72|uniprotkb:Q74UK4	intact:EBI-373637|uniprotkb:O75504|uniprotkb:D3DS51|ensembl:ENSP00000312442.5|ensembl:ENSP00000380309.3	psi-mi:astd_yerpe(display_long)|uniprotkb:astD(gene name)|psi-mi:astD(display_short)|uniprotkb:Succinylglutamic semialdehyde dehydrogenase(gene name synonym)|uniprotkb:YPO1964(locus name)|uniprotkb:y2347(locus name)|uniprotkb:YP_1709(locus name)	psi-mi:ap1g2_human(display_long)|uniprotkb:AP1G2(gene name)|psi-mi:AP1G2(display_short)|uniprotkb:Gamma2-adaptin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875979|imex:IM-13779-8343	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002212030.1|interpro:IPR029510|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR017649(Succinylglutamic semialdehyde dehydrogenase)|go:""GO:0019544""(arginine catabolic process to glutamate)|go:""GO:0019545""(arginine catabolic process to succinate)|go:""GO:0043824""(succinylglutamate-semialdehyde dehydrogenase activity)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:YP_002346953.1|panther:PTHR11699(orthology-group)"	"panther:PTHR22780(orthology-group)|refseq:NP_003908.1|refseq:XP_005268229.1|refseq:XP_005268230.1|ensembl:ENSG00000213983.12(gene)|ensembl:ENST00000308724.9(transcript)|ensembl:ENST00000397120.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030133""(transport vesicle)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0045202""(synapse)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|interpro:IPR050840|mint:O75843|rcsb pdb:2E9G|rcsb pdb:2YMT|rcsb pdb:3ZHF|rcsb pdb:4BCX|reactome:R-HSA-432720|dip:DIP-31185N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:lAw8pbIH2i1IjXZl8H7zAJvQj0I632	rogid:kqOQ44wfiFq2YxrDbVBvofbl9E89606	intact-crc:6FCDD96614DB4CCF|rigid:BCLlhY/qKvHjpHDYkvoEv2sJgxQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10567	uniprotkb:Q74R28	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	intact:EBI-2844649|uniprotkb:Q8D1I8	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:ugpc_yerpe(display_long)|uniprotkb:ugpC(gene name)|psi-mi:ugpC(display_short)|uniprotkb:YPO3793(locus name)|uniprotkb:y0437(locus name)|uniprotkb:YP_3256(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875993|imex:IM-13779-8344	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR040582|interpro:IPR015855(ABC transporter, maltose/maltodextrin import, MalK)|interpro:IPR027417|refseq:WP_002211523.1|go:""GO:0001407""(glycerophosphodiester transmembrane transport)|go:""GO:0005524""(ATP binding)|go:""GO:0008643""(carbohydrate transport)|go:""GO:0015430""(ABC-type glycerol-3-phosphate transporter activity)|go:""GO:0015794""(glycerol-3-phosphate transmembrane transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055052""(""ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing"")|interpro:IPR047641|refseq:YP_002348670.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR43875(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	rogid:NtRUgbRI2HE2UzUkxbSvyMnRkao632	intact-crc:51F47FF6FFDEE0BA|rigid:QsvUp95/mwPfmvjO7qrgBlP4Egs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VBG2	uniprotkb:Q10567	intact:EBI-2849663	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	psi-mi:a0a6b3vbg2_yerpe(display_long)|uniprotkb:yapB(gene name)|psi-mi:yapB(display_short)|uniprotkb:y1345(locus name)	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876007|imex:IM-13779-8347	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|uniprotkb:A0A6B3T6Y5(uniprot-removed-ac)|go:""GO:0019867""(outer membrane)|interpro:IPR051551"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jNPx4rqCv9bEZelj7jbp42kW+NY632	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	intact-crc:B010CD12EC2819FB|rigid:yTu9vcdEql8PEHK2fe/W4509sw4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10567	uniprotkb:Q8D184	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	intact:EBI-2848181|uniprotkb:Q74XL8	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:q8d184_yerpe(display_long)|uniprotkb:aroF(gene name)|psi-mi:aroF(display_short)|uniprotkb:NCTC5923_01037(orf name)|uniprotkb:YP_0398(locus name)|uniprotkb:y0903(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876000|imex:IM-13779-8345	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR006218(DAHP synthetase I/KDSA)|interpro:IPR006219(DHAP synthase, class 1)|go:""GO:0003849""(3-deoxy-7-phosphoheptulonate synthase activity)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0009073""(aromatic amino acid family biosynthetic process)|go:""GO:0009423""(chorismate biosynthetic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	rogid:4L95qW4AbphJFnq2t9Za1RWY2IQ632	intact-crc:210F935F2348AF59|rigid:Ob7EIv3kscJ5jznWwFm6ANAZ+Mc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43747	uniprotkb:A0A2U2H0Q2	intact:EBI-447609|uniprotkb:O75709|uniprotkb:O75842|uniprotkb:Q9UG09|uniprotkb:Q9Y3U4|ensembl:ENSP00000299980.4|ensembl:ENSP00000454523.1	intact:EBI-2849316|uniprotkb:Q74T97|uniprotkb:A0A0H2W5H0|uniprotkb:A0A380SBC9|uniprotkb:Q7CJ44|uniprotkb:A0A384KC05	psi-mi:ap1g1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit gamma-1(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin subunit gamma-1(gene name synonym)|uniprotkb:Gamma1-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 gamma-1 large chain(gene name synonym)|uniprotkb:AP1G1(gene name)|psi-mi:AP1G1(display_short)|uniprotkb:ADTG(gene name synonym)|uniprotkb:CLAPG1(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit gamma-1(gene name synonym)	psi-mi:a0a2u2h0q2_yerpe(display_long)|uniprotkb:YPO2473(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2875986|imex:IM-13779-8346	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166747.13(gene)|ensembl:ENST00000299980.9(transcript)|ensembl:ENST00000569748.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005518""(collagen binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0016020""(membrane)|go:""GO:0016182""(synaptic vesicle budding from endosome)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019894""(kinesin binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032438""(melanosome organization)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0055037""(recycling endosome)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0098793""(presynapse)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|interpro:IPR050840|mint:O43747|rcsb pdb:1IU1|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001025178.1|refseq:NP_001119.3|efo:""Orphanet:528084""|panther:PTHR22780(orthology-group)"	interpro:IPR015045(Protein of unknown function DUF1861)|interpro:IPR023296|refseq:WP_002213840.1|refseq:YP_002347437.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E0niV91xZ1PV6Pr6Koq3Xs+9nKg9606	rogid:O/NA0dkts3mvJMI8kSLzsoLX53I632	intact-crc:BFD04A47E9159883|rigid:nePsfRHlOrYtcY06Us0YV0m+pnE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10567	uniprotkb:A0A0H2W7E2	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	intact:EBI-2848155|uniprotkb:A0A2U2H0T1|uniprotkb:Q74QL8|uniprotkb:Q0WI49|uniprotkb:Q7CGN6|uniprotkb:A0A384KKB9	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:a0a0h2w7e2_yerpe(display_long)|uniprotkb:iutA(gene name)|psi-mi:iutA(display_short)|uniprotkb:YPO0994(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876028|imex:IM-13779-8351	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|refseq:WP_002211646.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002346039.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	rogid:h+zziPxtFmhqRng+3zCsRqmsI/M632	intact-crc:394624C7EE17F1AC|rigid:69/KszbFlYf8RI5Li2my0qaqCAE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10567	uniprotkb:Q8CZT6	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	intact:EBI-2863462	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:q8czt6_yerpe(display_long)|uniprotkb:y3428(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876014|imex:IM-13779-8352	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|interpro:IPR051551|go:""GO:0019867""(outer membrane)|interpro:IPR043990"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	rogid:MiLa9vLiNmbmMr4denBvKhQstG8632	intact-crc:17E1DA0823E5EF4F|rigid:UJuawA3puj6sjZDdACdYkALAn9I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10567	uniprotkb:A0A2U2GZD9	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	intact:EBI-2842164|uniprotkb:Q74PM4|uniprotkb:Q0WAY0|uniprotkb:Q7CL70|uniprotkb:A0A384L4X0	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:a0a2u2gzd9_yerpe(display_long)|uniprotkb:tldD(gene name)|psi-mi:tldD(display_short)|uniprotkb:YPO3672(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876021|imex:IM-13779-8348	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"interpro:IPR002510(Peptidase U62, modulator of DNA gyrase)|interpro:IPR025502|interpro:IPR035068|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|interpro:IPR036059|refseq:WP_002210082.1|refseq:YP_002348558.1|interpro:IPR051463|interpro:IPR045569|interpro:IPR045570|panther:PTHR30624(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	rogid:0A28kCnLbozYkMpV71fqiLReR8Y632	intact-crc:16DACAC90D689F0A|rigid:daTl8fxTzW8qY/SGJ5vPaL5AITs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YAV7	uniprotkb:Q10567	intact:EBI-2839792|uniprotkb:Q74QU9|uniprotkb:Q0WA24|uniprotkb:Q7CG16|uniprotkb:A0A0H2W8V3	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	psi-mi:a0a5p8yav7_yerpe(display_long)|uniprotkb:pelY(gene name)|psi-mi:pelY(display_short)|uniprotkb:YPO3994(locus name)	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876035|imex:IM-13779-8349	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010702(Periplasmic pectate lyase)|refseq:YP_002348864.1|refseq:WP_002209555.1|go:""GO:0016837""(carbon-oxygen lyase activity, acting on polysaccharides)|go:""GO:0042597""(periplasmic space)|go:""GO:0045490""(pectin catabolic process)"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TdSmcoWgW+r5eNyU5ieC4Vae68s632	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	intact-crc:F9E5C12D3F13375D|rigid:Bs73k9GoWaezzqkqo2Q4I2kaN60	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10567	uniprotkb:A0A2U2GXJ4	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	intact:EBI-2840915|uniprotkb:Q74Y41|uniprotkb:A0A384KPW0|uniprotkb:Q7CFX2|uniprotkb:Q0WKG9|uniprotkb:A0A0H2W132	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:a0a2u2gxj4_yerpe(display_long)|uniprotkb:feoA(gene name)|psi-mi:feoA(display_short)|uniprotkb:YPO0133(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876042|imex:IM-13779-8350	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"interpro:IPR007167(Ferrous iron transporter, FeoA subunit)|interpro:IPR008988(Transcriptional repressor, C-terminal)|refseq:YP_002345219.1|go:""GO:0046914""(transition metal ion binding)|interpro:IPR038157|refseq:WP_002208918.1|interpro:IPR052713"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	rogid:Cncvuchy10judg2RDKVdBo+4A/s632	intact-crc:6696636E34965B35|rigid:eSRZ2M25LIqoaOYJKf9rvX+Y8Cw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6UB98	uniprotkb:P17778	intact:EBI-2690224|uniprotkb:Q658K1|uniprotkb:Q6QMF7|uniprotkb:Q9H784|uniprotkb:O94951|uniprotkb:Q9H231|ensembl:ENSP00000262126.3	intact:EBI-2842665|uniprotkb:O68701	psi-mi:anr12_human(display_long)|uniprotkb:ANCO2(gene name synonym)|uniprotkb:KIAA0874(gene name synonym)|uniprotkb:Ankyrin repeat-containing cofactor 2(gene name synonym)|uniprotkb:GAC-1 protein(gene name synonym)|uniprotkb:ANKRD12(gene name)|psi-mi:ANKRD12(display_short)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876084|imex:IM-13779-8357	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_016881152.1|refseq:NP_001077094.1|refseq:NP_001190985.1|refseq:NP_056023.3|refseq:XP_005258149.1|refseq:XP_005258150.1|ensembl:ENSG00000101745.17(gene)|ensembl:ENST00000262126.9(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR053210|panther:PTHR24149(orthology-group)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:etb60/sLQAg6in0go8JlQEGA9Os9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:2546709944317243|rigid:EePN2RHLSEmSOQH1eC0szz+SQBM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZB39	uniprotkb:P20073	intact:EBI-2871408|uniprotkb:Q0WB65	intact:EBI-2338704|uniprotkb:Q5F2H3|uniprotkb:Q5T0M6|uniprotkb:Q5T0M7|ensembl:ENSP00000362010.4|intact:EBI-28973842	psi-mi:pyrb_yerpe(display_long)|uniprotkb:pyrB(gene name)|psi-mi:pyrB(display_short)|uniprotkb:Aspartate transcarbamylase(gene name synonym)|uniprotkb:YPO3588(locus name)|uniprotkb:y0161(locus name)|uniprotkb:YP_3842(locus name)	psi-mi:anxa7_human(display_long)|uniprotkb:ANXA7(gene name)|psi-mi:ANXA7(display_short)|uniprotkb:ANX7(gene name synonym)|uniprotkb:SNX(gene name synonym)|uniprotkb:Annexin-7(gene name synonym)|uniprotkb:Annexin VII(gene name synonym)|uniprotkb:Synexin(gene name synonym)|uniprotkb:OK/SW-cl.95(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876049|imex:IM-13779-8353	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|rcsb pdb:3LXM|refseq:WP_002210111.1|interpro:IPR036901|go:""GO:0004070""(aspartate carbamoyltransferase activity)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0016597""(amino acid binding)|go:""GO:0044205""('de novo' UMP biosynthetic process)|refseq:YP_002348473.1|panther:PTHR45753(orthology-group)"	"refseq:NP_001147.1|refseq:NP_004025.1|refseq:XP_016871651.1|refseq:XP_016871652.1|ensembl:ENSG00000138279.16(gene)|ensembl:ENST00000372919.8(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006914""(autophagy)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P20073|rcsb pdb:8W5S|ensembl:ENSP00000362010.4|ensembl:ENST00000372921.10|ensembl:ENSP00000362012.4|panther:PTHR10502(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:q1IN/nMvnIDiJRIMwW0/Gb4gofM632	rogid:ad3I49rhRoZ0hG8ruDgSQWocVuw9606	intact-crc:0128AF34919A4BD7|rigid:Fhw4TiA/DjxuqQ1veUZdPHIERiw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZDX4	uniprotkb:P20073	intact:EBI-2854297|uniprotkb:Q0WEA0	intact:EBI-2338704|uniprotkb:Q5F2H3|uniprotkb:Q5T0M6|uniprotkb:Q5T0M7|ensembl:ENSP00000362010.4|intact:EBI-28973842	psi-mi:btuc_yerpe(display_long)|uniprotkb:btuC(gene name)|psi-mi:btuC(display_short)|uniprotkb:YPO2425(locus name)|uniprotkb:y1914(locus name)|uniprotkb:YP_2212(locus name)	psi-mi:anxa7_human(display_long)|uniprotkb:ANXA7(gene name)|psi-mi:ANXA7(display_short)|uniprotkb:ANX7(gene name synonym)|uniprotkb:SNX(gene name synonym)|uniprotkb:Annexin-7(gene name synonym)|uniprotkb:Annexin VII(gene name synonym)|uniprotkb:Synexin(gene name synonym)|uniprotkb:OK/SW-cl.95(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876056|imex:IM-13779-8356	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023691|interpro:IPR000522(Bacterial transport system permease protein)|refseq:WP_002220283.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015889""(cobalamin transport)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0090482""(vitamin transmembrane transporter activity)|interpro:IPR037294|refseq:YP_002347388.1|panther:PTHR30472(orthology-group)"	"refseq:NP_001147.1|refseq:NP_004025.1|refseq:XP_016871651.1|refseq:XP_016871652.1|ensembl:ENSG00000138279.16(gene)|ensembl:ENST00000372919.8(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006914""(autophagy)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P20073|rcsb pdb:8W5S|ensembl:ENSP00000362010.4|ensembl:ENST00000372921.10|ensembl:ENSP00000362012.4|panther:PTHR10502(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VbgN61SjIkXmwpfgZz3xo6Um6Cc632	rogid:ad3I49rhRoZ0hG8ruDgSQWocVuw9606	intact-crc:3EBC893492478E6E|rigid:+eokiMAISzqwJcrQGsXYpJ1HT24	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08758	uniprotkb:P17778	intact:EBI-296601|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|ensembl:ENSP00000296511.5|uniprotkb:D3DNW7	intact:EBI-2842665|uniprotkb:O68701	psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876063|imex:IM-13779-8354	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001145.1|ensembl:ENSG00000164111.15(gene)|ensembl:ENST00000296511.10(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0004859""(phospholipase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007596""(blood coagulation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0050819""(negative regulation of coagulation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072563""(endothelial microparticle)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|rcsb pdb:8GYC|rcsb pdb:8H0J|rcsb pdb:8H9Z|reactome:R-HSA-114608|panther:PTHR10502(orthology-group)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:EB438F4D5D05DA10|rigid:jLMFkT7K6R4B3XfiW5WVcLTtFJ4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6NY19	uniprotkb:Q8ZFX5	intact:EBI-2876070|ensembl:ENSP00000328923.2|uniprotkb:Q6NZI1|uniprotkb:Q6ZQR3|uniprotkb:Q8IUV2	intact:EBI-2851740|uniprotkb:Q0WGM4	psi-mi:kank3_human(display_long)|uniprotkb:KANK3(gene name)|psi-mi:KANK3(display_short)|uniprotkb:ANKRD47(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 47(gene name synonym)	psi-mi:hisx_yerpe(display_long)|uniprotkb:hisD(gene name)|psi-mi:hisD(display_short)|uniprotkb:YPO1548(locus name)|uniprotkb:y2621(locus name)|uniprotkb:YP_1437(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876077|imex:IM-13779-8355	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000186994.12(gene)|ensembl:ENST00000330915.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0030837""(negative regulation of actin filament polymerization)|interpro:IPR002110(Ankyrin)|interpro:IPR021939|interpro:IPR036770|interpro:IPR047184|refseq:XP_011526186.1|refseq:NP_940873.2|refseq:XP_006722781.1|panther:PTHR24168(orthology-group)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR001692(Histidinol dehydrogenase)|interpro:IPR022695|interpro:IPR012131(Histidinol dehydrogenase, prokaryotic)|refseq:WP_002211895.1|go:""GO:0000105""(L-histidine biosynthetic process)|go:""GO:0004399""(histidinol dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0051287""(NAD binding)|refseq:YP_002346564.1|panther:PTHR21256(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:50iZoLgAUJne1Ss3NgeCS1k619c9606	rogid:aXT+/ioqFLvYG1ayljhfqLE1ikU632	intact-crc:76742D98B5ED5A52|rigid:YB9U2sE2J+tRUvAy81gy6219K/Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B749	uniprotkb:Q01484	intact:EBI-2842996|uniprotkb:Q74V98|uniprotkb:Q0WGP3|uniprotkb:Q7CHR5|uniprotkb:A0A384LAC1	intact:EBI-941975|uniprotkb:Q01485|uniprotkb:Q08AC7|uniprotkb:Q08AC8|uniprotkb:Q7Z3L5|ensembl:ENSP00000349588.4	psi-mi:a0a3n4b749_yerpe(display_long)|uniprotkb:YPO1529(locus name)	psi-mi:ank2_human(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876098|imex:IM-13779-8358	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010977(Aromatic-L-amino-acid decarboxylase)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002211877.1|go:""GO:0005737""(cytoplasm)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0016831""(carboxy-lyase activity)|go:""GO:0019752""(carboxylic acid metabolic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:YP_002346545.1|panther:PTHR45677(orthology-group)"	"ensembl:ENSG00000145362.21(gene)|ensembl:ENST00000357077.9(transcript)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0003283""(atrial septum development)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006897""(endocytosis)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008104""(protein localization)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0010882""(regulation of cardiac muscle contraction by calcium ion signaling)|go:""GO:0014704""(intercalated disc)|go:""GO:0015031""(protein transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0030315""(T-tubule)|go:""GO:0030507""(spectrin binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030913""(paranodal junction assembly)|go:""GO:0031430""(M band)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031672""(A band)|go:""GO:0033292""(T-tubule organization)|go:""GO:0033365""(protein localization to organelle)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0036309""(protein localization to M-band)|go:""GO:0036371""(protein localization to T-tubule)|go:""GO:0042383""(sarcolemma)|go:""GO:0043005""(neuron projection)|go:""GO:0043034""(costamere)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0050821""(protein stabilization)|go:""GO:0051117""(ATPase binding)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051597""(response to methylmercury)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0055037""(recycling endosome)|go:""GO:0055117""(regulation of cardiac muscle contraction)|go:""GO:0060307""(regulation of ventricular cardiac muscle cell membrane repolarization)|go:""GO:0070296""(sarcoplasmic reticulum calcium ion transport)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0086004""(regulation of cardiac muscle cell contraction)|go:""GO:0086005""(ventricular cardiac muscle cell action potential)|go:""GO:0086014""(atrial cardiac muscle cell action potential)|go:""GO:0086015""(SA node cell action potential)|go:""GO:0086046""(membrane depolarization during SA node cell action potential)|go:""GO:0086066""(atrial cardiac muscle cell to AV node cell communication)|go:""GO:0086070""(SA node cell to atrial cardiac muscle cell communication)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0098907""(regulation of SA node cell action potential)|go:""GO:0098910""(regulation of atrial cardiac muscle cell action potential)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:1901018""(positive regulation of potassium ion transmembrane transporter activity)|go:""GO:1901019""(regulation of calcium ion transmembrane transporter activity)|go:""GO:1901021""(positive regulation of calcium ion transmembrane transporter activity)|go:""GO:2001259""(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR036770|interpro:IPR040745|interpro:IPR051165|mint:Q01484|rcsb pdb:4D8O|rcsb pdb:4RLV|rcsb pdb:4RLY|rcsb pdb:5Y4D|rcsb pdb:5Y4E|rcsb pdb:5Y4F|rcsb pdb:5YIR|rcsb pdb:5YIS|rcsb pdb:6KZJ|rcsb pdb:6M3Q|reactome:R-HSA-445095|reactome:R-HSA-6807878|refseq:NP_001120965.1|refseq:NP_001139.3|refseq:NP_066187.2|dip:DIP-37425N|efo:""Orphanet:101016""|panther:PTHR24133(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Uex6pAvRG3FNG1VCbilPXw5bliY632	rogid:wHoFDw3CIP2xOUZj9WzEMGm/z8k9606	intact-crc:AE336A241DB86C80|rigid:3cX34WazYsHf3ygIyru/6IAMk8E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O68743	uniprotkb:Q01484	intact:EBI-2849869|uniprotkb:A0A384L9N9|uniprotkb:Q74YP1|uniprotkb:Q7ARA6|uniprotkb:Q7BT23|uniprotkb:Q65AP4|uniprotkb:A0A1U8QGX5|uniprotkb:A0A5P8YM11|uniprotkb:A0A2U2H133	intact:EBI-941975|uniprotkb:Q01485|uniprotkb:Q08AC7|uniprotkb:Q08AC8|uniprotkb:Q7Z3L5|ensembl:ENSP00000349588.4	psi-mi:o68743_yerpe(display_long)|uniprotkb:YPMT1.25Ac(gene name)|psi-mi:YPMT1.25Ac(display_short)	psi-mi:ank2_human(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876105|imex:IM-13779-8359	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_857662.1|refseq:NP_395362.1|refseq:YP_093903.1|refseq:WP_000176291.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:O68743"	"ensembl:ENSG00000145362.21(gene)|ensembl:ENST00000357077.9(transcript)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0003283""(atrial septum development)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005739""(mitochondrion)|go:""GO:0005764""(lysosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006897""(endocytosis)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008104""(protein localization)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0010882""(regulation of cardiac muscle contraction by calcium ion signaling)|go:""GO:0014704""(intercalated disc)|go:""GO:0015031""(protein transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0030315""(T-tubule)|go:""GO:0030507""(spectrin binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030913""(paranodal junction assembly)|go:""GO:0031430""(M band)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031672""(A band)|go:""GO:0033292""(T-tubule organization)|go:""GO:0033365""(protein localization to organelle)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0036309""(protein localization to M-band)|go:""GO:0036371""(protein localization to T-tubule)|go:""GO:0042383""(sarcolemma)|go:""GO:0043005""(neuron projection)|go:""GO:0043034""(costamere)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0050821""(protein stabilization)|go:""GO:0051117""(ATPase binding)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051597""(response to methylmercury)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0055037""(recycling endosome)|go:""GO:0055117""(regulation of cardiac muscle contraction)|go:""GO:0060307""(regulation of ventricular cardiac muscle cell membrane repolarization)|go:""GO:0070296""(sarcoplasmic reticulum calcium ion transport)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0086004""(regulation of cardiac muscle cell contraction)|go:""GO:0086005""(ventricular cardiac muscle cell action potential)|go:""GO:0086014""(atrial cardiac muscle cell action potential)|go:""GO:0086015""(SA node cell action potential)|go:""GO:0086046""(membrane depolarization during SA node cell action potential)|go:""GO:0086066""(atrial cardiac muscle cell to AV node cell communication)|go:""GO:0086070""(SA node cell to atrial cardiac muscle cell communication)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0098907""(regulation of SA node cell action potential)|go:""GO:0098910""(regulation of atrial cardiac muscle cell action potential)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:1901018""(positive regulation of potassium ion transmembrane transporter activity)|go:""GO:1901019""(regulation of calcium ion transmembrane transporter activity)|go:""GO:1901021""(positive regulation of calcium ion transmembrane transporter activity)|go:""GO:2001259""(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR036770|interpro:IPR040745|interpro:IPR051165|mint:Q01484|rcsb pdb:4D8O|rcsb pdb:4RLV|rcsb pdb:4RLY|rcsb pdb:5Y4D|rcsb pdb:5Y4E|rcsb pdb:5Y4F|rcsb pdb:5YIR|rcsb pdb:5YIS|rcsb pdb:6KZJ|rcsb pdb:6M3Q|reactome:R-HSA-445095|reactome:R-HSA-6807878|refseq:NP_001120965.1|refseq:NP_001139.3|refseq:NP_066187.2|dip:DIP-37425N|efo:""Orphanet:101016""|panther:PTHR24133(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/jUgpNFZ2rE3SwY62pqgY9qM8xs632	rogid:wHoFDw3CIP2xOUZj9WzEMGm/z8k9606	intact-crc:AA0263C46839AB58|rigid:CHwtfjmWY2t2LwZNzb37hoP41RE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLC4	uniprotkb:Q6UB98	intact:EBI-2844860	intact:EBI-2690224|uniprotkb:Q658K1|uniprotkb:Q6QMF7|uniprotkb:Q9H784|uniprotkb:O94951|uniprotkb:Q9H231|ensembl:ENSP00000262126.3	psi-mi:q8clc4_yerpe(display_long)|uniprotkb:y1644(locus name)	psi-mi:anr12_human(display_long)|uniprotkb:ANCO2(gene name synonym)|uniprotkb:KIAA0874(gene name synonym)|uniprotkb:Ankyrin repeat-containing cofactor 2(gene name synonym)|uniprotkb:GAC-1 protein(gene name synonym)|uniprotkb:ANKRD12(gene name)|psi-mi:ANKRD12(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876091|imex:IM-13779-8360	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR004375(Conserved hypothetical protein CHP00022)|interpro:IPR037012	"refseq:XP_016881152.1|refseq:NP_001077094.1|refseq:NP_001190985.1|refseq:NP_056023.3|refseq:XP_005258149.1|refseq:XP_005258150.1|ensembl:ENSG00000101745.17(gene)|ensembl:ENST00000262126.9(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR053210|panther:PTHR24149(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bRggnpBtWSjyBJTLgvdTftsIYl4632	rogid:etb60/sLQAg6in0go8JlQEGA9Os9606	intact-crc:0336EFEB63C7E758|rigid:AXtrNFC4daZaPC6ZtYDsiLAoefI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31491	uniprotkb:Q8N2N9	intact:EBI-2840013	intact:EBI-2876112|ensembl:ENSP00000477778.1|ensembl:ENSP00000481149.1|ensembl:ENSP00000517103.1|ensembl:ENSP00000517104.1|uniprotkb:Q96N30|uniprotkb:Q9H759|uniprotkb:Q6PI49|uniprotkb:Q08AK5|uniprotkb:Q8IZM7|uniprotkb:Q8TDH6|uniprotkb:Q6IPR0	psi-mi:yera_yerpe(display_long)|uniprotkb:yerA(gene name)|psi-mi:yerA(display_short)|uniprotkb:YPCD1.05c(locus name)|uniprotkb:y5069(locus name)|uniprotkb:y0078(locus name)|uniprotkb:YP_pCD82(locus name)	psi-mi:an36b_human(display_long)|uniprotkb:ANKRD36B(gene name)|psi-mi:ANKRD36B(display_short)|uniprotkb:CLL-associated antigen KW-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876124|imex:IM-13779-8361	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395142.1|refseq:NP_857763.1|refseq:NP_857968.1|interpro:IPR005416(Type III secretion chaperone SycE, Gram-negative bacterial)|interpro:IPR010261(Tir chaperone)|go:""GO:0030254""(protein secretion by the type III secretion system)|rcsb pdb:1JYA|rcsb pdb:1K6Z|refseq:WP_002213403.1|mint:P31491"	"ensembl:ENSG00000196912.13(gene)|ensembl:ENSG00000291600.1(gene)|ensembl:ENST00000258459.12(transcript)|ensembl:ENST00000359901.9(transcript)|ensembl:ENST00000708143.1(transcript)|ensembl:ENST00000708145.1(transcript)|go:""GO:0042802""(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR039497|interpro:IPR050657|refseq:NP_079466.3|refseq:XP_006712724.1|refseq:XP_005264052.1|panther:PTHR24147(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qrGc2l9rhnr0MEOXqSUh/YZ9d6E632	rogid:V95mb2P58K6M8EKw3jwBjL+J1FM9606	intact-crc:2629375E5F56FDCC|rigid:COTpvaQ3EXZThX3O3QvFdMjc34U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P39687	uniprotkb:Q8ZFX5	intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864.2	intact:EBI-2851740|uniprotkb:Q0WGM4	psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym)	psi-mi:hisx_yerpe(display_long)|uniprotkb:hisD(gene name)|psi-mi:hisD(display_short)|uniprotkb:YPO1548(locus name)|uniprotkb:y2621(locus name)|uniprotkb:YP_1437(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876138|imex:IM-13779-8363	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006296.1|ensembl:ENSG00000140350.15(gene)|ensembl:ENST00000465139.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042393""(histone binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR045081|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|rcsb pdb:8RMR|rcsb pdb:8RN0|rcsb pdb:8RNA|rcsb pdb:8RNB|rcsb pdb:8RNC|reactome:R-HSA-450520|panther:PTHR11375(orthology-group)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR001692(Histidinol dehydrogenase)|interpro:IPR022695|interpro:IPR012131(Histidinol dehydrogenase, prokaryotic)|refseq:WP_002211895.1|go:""GO:0000105""(L-histidine biosynthetic process)|go:""GO:0004399""(histidinol dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0051287""(NAD binding)|refseq:YP_002346564.1|panther:PTHR21256(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606	rogid:aXT+/ioqFLvYG1ayljhfqLE1ikU632	intact-crc:E01D302C1DFBF6B8|rigid:8xGVssIpjoTySraJE6UF+3dHwrY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C0C7	uniprotkb:Q7CJF3	intact:EBI-2512975|uniprotkb:Q86XD6|uniprotkb:A6XN33|uniprotkb:Q9NXE7|uniprotkb:Q9H8Z0|intact:EBI-2556181|ensembl:ENSP00000415327.2|ensembl:ENSP00000508322.1|uniprotkb:D3DQP8|uniprotkb:G3V193	intact:EBI-2846856|uniprotkb:Q74SI9	psi-mi:amra1_human(display_long)|uniprotkb:AMBRA1(gene name)|psi-mi:AMBRA1(display_short)|uniprotkb:DCAF3(gene name synonym)|uniprotkb:DDB1- and CUL4-associated factor 3(gene name synonym)|uniprotkb:KIAA1736(gene name synonym)	"psi-mi:dnlj_yerpe(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:""Polydeoxyribonucleotide synthase [NAD(+)]""(gene name synonym)|uniprotkb:YPO2989(locus name)|uniprotkb:YP_2614(locus name)|uniprotkb:y1492(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876164|imex:IM-13779-8364	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110497.15(gene)|ensembl:ENST00000458649.6(transcript)|ensembl:ENST00000683756.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000423""(mitophagy)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005776""(autophagosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0005930""(axoneme)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021915""(neural tube development)|go:""GO:0030154""(cell differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045591""(positive regulation of regulatory T cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051020""(GTPase binding)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|go:""GO:0098780""(response to mitochondrial depolarisation)|go:""GO:1901526""(positive regulation of mitophagy)|go:""GO:1904544""(positive regulation of free ubiquitin chain polymerization)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR052596|mint:Q9C0C7|rcsb pdb:8WQR|reactome:R-HSA-1632852|refseq:NP_060219.2|refseq:NP_001254711.1|refseq:NP_001254712.1|refseq:XP_005253066.1|refseq:XP_005253068.1|refseq:XP_005253071.1|refseq:XP_006718322.1|refseq:NP_001287660.1|dip:DIP-53597N|panther:PTHR22874(orthology-group)"	"interpro:IPR033136|interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR004149(Zinc-finger, NAD-dependent DNA ligase C4-type)|refseq:WP_002213368.1|go:""GO:0003677""(DNA binding)|go:""GO:0003911""(""DNA ligase (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006288""(obsolete base-excision repair, DNA ligation)|go:""GO:0046872""(metal ion binding)|interpro:IPR036420|interpro:IPR041663|refseq:YP_002347913.1|panther:PTHR23389(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:h4yD2iL711peDzI4kttngSdTLQk9606	rogid:ABzJi1jMOUD1WGHNwTu2zo0ozls632	intact-crc:93019AC7918AC9A8|rigid:Z190WrgQMTdZCORZCB6xWbDsTDI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q8IZ07	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-2876152|ensembl:ENSP00000261739.4|uniprotkb:O60736	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:an13a_human(display_long)|uniprotkb:ANKRD13A(gene name)|psi-mi:ANKRD13A(display_short)|uniprotkb:ANKRD13(gene name synonym)|uniprotkb:Protein KE03(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876157|imex:IM-13779-8362	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"ensembl:ENSG00000076513.17(gene)|ensembl:ENST00000261739.9(transcript)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0005737""(cytoplasm)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0140036""(ubiquitin-modified protein reader activity)|go:""GO:1905667""(negative regulation of protein localization to endosome)|interpro:IPR002110(Ankyrin)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR021832|interpro:IPR036770|interpro:IPR055285|mint:Q8IZ07|refseq:NP_149112.1|panther:PTHR12447(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:RI4K5f4Ks8YSRYUO/FEQNCRkI389606	intact-crc:ED83F3B4A72405A1|rigid:suLdIPTg8w7srRMflNDDTYoEEaU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZTN6	uniprotkb:A0A5P8YBQ9	intact:EBI-947028|uniprotkb:Q0VAK0|uniprotkb:Q6ZVD0|uniprotkb:Q86SU1|uniprotkb:D6RCN6|uniprotkb:Q0VGC3|ensembl:ENSP00000427130.2	intact:EBI-2844830|uniprotkb:Q74X93|uniprotkb:A0A0H2W369|uniprotkb:Q7CKK6|uniprotkb:A0A2U2GXX7|uniprotkb:A0A384KXD1	psi-mi:an13d_human(display_long)|uniprotkb:ANKRD13D(gene name)|psi-mi:ANKRD13D(display_short)	psi-mi:a0a5p8ybq9_yerpe(display_long)|uniprotkb:YPO3526(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876145|imex:IM-13779-8365	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_997237.2|refseq:NP_001334830.1|ensembl:ENSG00000172932.16(gene)|ensembl:ENST00000511455.7(transcript)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0005737""(cytoplasm)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0140036""(ubiquitin-modified protein reader activity)|interpro:IPR002110(Ankyrin)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR021832|interpro:IPR036770|interpro:IPR055285|rcsb pdb:7RMA|panther:PTHR12447(orthology-group)"	"interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR005170(Transporter-associated region)|interpro:IPR044751|go:""GO:0005886""(plasma membrane)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_002210164.1|interpro:IPR036318|refseq:YP_002348415.1|interpro:IPR046342"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PnNGSoPIrih0F3fUD5AikA6Z5P89606	rogid:JC3IVKKYgEftNqAeJWJ+daHPtRo632	intact-crc:69453BBA97A0CC15|rigid:cMYe3UxCAEGo7BrhDYolYuTbm7A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N2N9	uniprotkb:A0A5P8YBQ9	intact:EBI-2876112|ensembl:ENSP00000477778.1|ensembl:ENSP00000481149.1|ensembl:ENSP00000517103.1|ensembl:ENSP00000517104.1|uniprotkb:Q96N30|uniprotkb:Q9H759|uniprotkb:Q6PI49|uniprotkb:Q08AK5|uniprotkb:Q8IZM7|uniprotkb:Q8TDH6|uniprotkb:Q6IPR0	intact:EBI-2844830|uniprotkb:Q74X93|uniprotkb:A0A0H2W369|uniprotkb:Q7CKK6|uniprotkb:A0A2U2GXX7|uniprotkb:A0A384KXD1	psi-mi:an36b_human(display_long)|uniprotkb:ANKRD36B(gene name)|psi-mi:ANKRD36B(display_short)|uniprotkb:CLL-associated antigen KW-1(gene name synonym)	psi-mi:a0a5p8ybq9_yerpe(display_long)|uniprotkb:YPO3526(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876131|imex:IM-13779-8366	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000196912.13(gene)|ensembl:ENSG00000291600.1(gene)|ensembl:ENST00000258459.12(transcript)|ensembl:ENST00000359901.9(transcript)|ensembl:ENST00000708143.1(transcript)|ensembl:ENST00000708145.1(transcript)|go:""GO:0042802""(identical protein binding)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR039497|interpro:IPR050657|refseq:NP_079466.3|refseq:XP_006712724.1|refseq:XP_005264052.1|panther:PTHR24147(orthology-group)"	"interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR005170(Transporter-associated region)|interpro:IPR044751|go:""GO:0005886""(plasma membrane)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_002210164.1|interpro:IPR036318|refseq:YP_002348415.1|interpro:IPR046342"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:V95mb2P58K6M8EKw3jwBjL+J1FM9606	rogid:JC3IVKKYgEftNqAeJWJ+daHPtRo632	intact-crc:3E23737F1994125E|rigid:GvuhvmUDUR8bRpTQgXNm1YF69sw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96B36	uniprotkb:Q8D0T7	intact:EBI-720593|uniprotkb:J3KPM3|uniprotkb:Q96BI4|uniprotkb:Q96IK7|uniprotkb:Q96NG2|uniprotkb:Q9BWR5|uniprotkb:A8MTQ1|uniprotkb:B2RE93|ensembl:ENSP00000341698.5|ensembl:ENSP00000375707.1|ensembl:ENSP00000375708.3|ensembl:ENSP00000375709.1|ensembl:ENSP00000375710.2	intact:EBI-2876199|uniprotkb:Q74T08	psi-mi:akts1_human(display_long)|uniprotkb:40 kDa proline-rich AKT substrate(gene name synonym)|uniprotkb:AKT1S1(gene name)|psi-mi:AKT1S1(display_short)|uniprotkb:PRAS40(gene name synonym)	psi-mi:q8d0t7_yerpe(display_long)|uniprotkb:hisJ(gene name)|psi-mi:hisJ(display_short)|uniprotkb:YP_2390(locus name)|uniprotkb:y1607(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876204|imex:IM-13779-8371	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001092102.1|refseq:NP_001092103.1|refseq:NP_001265088.1|refseq:NP_001265089.1|refseq:NP_115751.3|ensembl:ENSG00000204673.11(gene)|ensembl:ENST00000344175.10(transcript)|ensembl:ENST00000391831.5(transcript)|ensembl:ENST00000391832.7(transcript)|ensembl:ENST00000391833.5(transcript)|ensembl:ENST00000391834.6(transcript)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0030291""(protein serine/threonine kinase inhibitor activity)|go:""GO:0031931""(TORC1 complex)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043523""(regulation of neuron apoptotic process)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0048011""(neurotrophin TRK receptor signaling pathway)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR026682|interpro:IPR055192|mint:Q96B36|rcsb pdb:5WBL|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:6SB0|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-198323|reactome:R-HSA-3371571|reactome:R-HSA-5674400|panther:PTHR21844(orthology-group)|ensembl:ENSP00000341698.5|ensembl:ENSP00000375707.1|ensembl:ENSP00000375708.3|ensembl:ENSP00000375709.1|ensembl:ENSP00000375710.2|ensembl:ENST00000391835.1|ensembl:ENSP00000375711.1"	"go:""GO:0016020""(membrane)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|interpro:IPR005768(Lysine-arginine-ornithine-binding periplasmic protein)|interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR018313"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Capqfe8k0cG3E3nLJskNIEAkBfI9606	rogid:9iS69dshYc0rzZA9i5/AveNonY4632	intact-crc:173061D544F9FB40|rigid:VuFkH+8nO6EAQMKnUqZhli0vD/c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49189	uniprotkb:Q8ZHZ5	intact:EBI-1055313|uniprotkb:B2R6X1|uniprotkb:Q6LCL1|uniprotkb:Q9NZT7|uniprotkb:Q5VV90|uniprotkb:B4DXY7|uniprotkb:B9EKV4	intact:EBI-2858039|uniprotkb:Q74RJ1|uniprotkb:Q0WIU8|uniprotkb:Q7CGL0	psi-mi:al9a1_human(display_long)|uniprotkb:Aldehyde dehydrogenase family 9 member A1(gene name synonym)|uniprotkb:Aldehyde dehydrogenase E3 isozyme(gene name synonym)|uniprotkb:Gamma-aminobutyraldehyde dehydrogenase(gene name synonym)|uniprotkb:R-aminobutyraldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH9A1(gene name)|psi-mi:ALDH9A1(display_short)|uniprotkb:ALDH7(gene name synonym)|uniprotkb:ALDH9(gene name synonym)|uniprotkb:ALDH4(gene name synonym)|uniprotkb:Formaldehyde dehydrogenase(gene name synonym)	psi-mi:flgh1_yerpe(display_long)|uniprotkb:flgH1(gene name)|psi-mi:flgH1(display_short)|uniprotkb:Basal body L-ring protein 1(gene name synonym)|uniprotkb:YPO0729(locus name)|uniprotkb:y3449(locus name)|uniprotkb:YP_3040(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876192|imex:IM-13779-8369	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000687.3|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|refseq:XP_011507596.1|interpro:IPR029510|mint:P49189|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|go:""GO:0004029""(""aldehyde dehydrogenase (NAD+) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006081""(aldehyde metabolic process)|go:""GO:0018467""(""formaldehyde dehydrogenase (NAD+) activity"")|go:""GO:0019145""(""aminobutyraldehyde dehydrogenase (NAD+) activity"")|go:""GO:0036094""(small molecule binding)|go:""GO:0045329""(carnitine biosynthetic process)|go:""GO:0047105""(4-trimethylammoniobutyraldehyde dehydrogenase activity)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070062""(extracellular exosome)|rcsb pdb:6QAK|rcsb pdb:6QAO|rcsb pdb:6QAP|rcsb pdb:6VR6|rcsb pdb:6VWF|reactome:R-HSA-71262|panther:PTHR11699(orthology-group)"	"interpro:IPR000527(Flagellar L-ring protein)|refseq:WP_002211429.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009427""(bacterial-type flagellum basal body, distal rod, L ring)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:YP_002345790.1|panther:PTHR34933(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MYde00UETppWGSEKa35Jsck7Joc9606	rogid:Q+NSfLft869SSbjMsvF1Op2i/nU632	intact-crc:1034F21E5140839C|rigid:8qZBLa9UqoJINry4duEGPYYntwU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01432	uniprotkb:Q9X6B0	intact:EBI-1223554|uniprotkb:B7Z2S2|uniprotkb:B7Z877|uniprotkb:A0AUX0|uniprotkb:B7Z763|ensembl:ENSP00000379801.2|ensembl:ENSP00000431648.1	intact:EBI-2844324|intact:EBI-2856296|uniprotkb:Q0WBX3	psi-mi:ampd3_human(display_long)|uniprotkb:AMPD3(gene name)|psi-mi:AMPD3(display_short)|uniprotkb:AMP deaminase isoform E(gene name synonym)|uniprotkb:Erythrocyte AMP deaminase(gene name synonym)	psi-mi:katg_yerpe(display_long)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)|uniprotkb:katY(gene name synonym)|uniprotkb:Antigen 5(gene name synonym)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:YPO3319(locus name)|uniprotkb:y0870(locus name)|uniprotkb:YP_0367(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876178|imex:IM-13779-8370	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:45""|ensembl:ENSG00000133805.16(gene)|ensembl:ENST00000396553.7(transcript)|ensembl:ENST00000529507.5(transcript)|go:""GO:0003876""(AMP deaminase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0006188""(IMP biosynthetic process)|go:""GO:0006196""(AMP catabolic process)|go:""GO:0032264""(IMP salvage)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0046033""(AMP metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR006329(AMP deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR032466|reactome:R-HSA-6798695|reactome:R-HSA-74217|refseq:NP_000471.1|refseq:NP_001020560.1|refseq:NP_001020561.1|refseq:NP_001165901.1|refseq:NP_001165902.1|panther:PTHR11359(orthology-group)"	"interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|go:""GO:0004096""(catalase activity)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|refseq:WP_002209433.1|refseq:YP_002348215.1|panther:PTHR30555(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DDTj/Mk3f7elrnio3/uZZpWlrz09606	rogid:RBebELhpxkVGfQv9Ix9rW4jzmpE632	intact-crc:3DBC1C0AD57EFBEF|rigid:rnogy08Uw1+TXzCCwpG471kTvNc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P05091	uniprotkb:A0A5P8YCV0	intact:EBI-711703|ensembl:ENSP00000261733.2|uniprotkb:Q03639|uniprotkb:Q6IB13|uniprotkb:Q6IV71|uniprotkb:B4DW54|uniprotkb:E7EUE5	intact:EBI-2847775|uniprotkb:Q74Q84|uniprotkb:Q0WIC7|uniprotkb:Q7CGS8|uniprotkb:A0A384L1X8	psi-mi:aldh2_human(display_long)|uniprotkb:ALDH class 2(gene name synonym)|uniprotkb:ALDHI(gene name synonym)|uniprotkb:ALDH-E2(gene name synonym)|uniprotkb:ALDH2(gene name)|psi-mi:ALDH2(display_short)|uniprotkb:ALDM(gene name synonym)	psi-mi:a0a5p8ycv0_yerpe(display_long)|uniprotkb:YPO0913(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876185|imex:IM-13779-8368	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111275.13(gene)|ensembl:ENST00000261733.7(transcript)|go:""GO:0004029""(""aldehyde dehydrogenase (NAD+) activity"")|go:""GO:0004030""(""aldehyde dehydrogenase [NAD(P)+] activity"")|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006066""(alcohol metabolic process)|go:""GO:0006068""(ethanol catabolic process)|go:""GO:0008957""(""phenylacetaldehyde dehydrogenase (NAD+) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0018937""(nitroglycerin metabolic process)|go:""GO:0046185""(aldehyde catabolic process)|go:""GO:0051287""(NAD binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106435""(carboxylesterase activity)|go:""GO:1903179""(regulation of dopamine biosynthetic process)|go:""GO:1905627""(regulation of serotonin biosynthetic process)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P05091|rcsb pdb:1CW3|rcsb pdb:1NZW|rcsb pdb:1NZX|rcsb pdb:1NZZ|rcsb pdb:1O00|rcsb pdb:1O01|rcsb pdb:1O02|rcsb pdb:1O04|rcsb pdb:1O05|rcsb pdb:1ZUM|rcsb pdb:2ONM|rcsb pdb:2ONN|rcsb pdb:2ONO|rcsb pdb:2ONP|rcsb pdb:2VLE|rcsb pdb:3INJ|rcsb pdb:3INL|rcsb pdb:3N80|rcsb pdb:3N81|rcsb pdb:3N82|rcsb pdb:3N83|rcsb pdb:3SZ9|rcsb pdb:4FQF|rcsb pdb:4FR8|rcsb pdb:4KWF|rcsb pdb:4KWG|rcsb pdb:5L13|rcsb pdb:8DR9|rcsb pdb:8SHS|reactome:R-HSA-380612|reactome:R-HSA-445355|reactome:R-HSA-71384|reactome:R-HSA-9837999|refseq:NP_000681.2|refseq:NP_001191818.1|dip:DIP-40262N|panther:PTHR11699(orthology-group)"	"interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|refseq:WP_002209955.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009396""(folic acid-containing compound biosynthetic process)|go:""GO:0030272""(5-formyltetrahydrofolate cyclo-ligase activity)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|interpro:IPR024185|interpro:IPR037171|refseq:YP_002345961.1|panther:PTHR23407(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:XvszkFUJP4cXHCYokY16c+LeDEI9606	rogid:10+1hunnZ1E8GkdgkFMuY64dDRY632	intact-crc:147541B6F3C3E671|rigid:RgMHcn0Zk7U5FUG36wSCVLUad2Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C0C7	uniprotkb:Q8ZIE7	intact:EBI-2512975|uniprotkb:Q86XD6|uniprotkb:A6XN33|uniprotkb:Q9NXE7|uniprotkb:Q9H8Z0|intact:EBI-2556181|ensembl:ENSP00000415327.2|ensembl:ENSP00000508322.1|uniprotkb:D3DQP8|uniprotkb:G3V193	intact:EBI-2870020|uniprotkb:Q0WJB0	psi-mi:amra1_human(display_long)|uniprotkb:AMBRA1(gene name)|psi-mi:AMBRA1(display_short)|uniprotkb:DCAF3(gene name synonym)|uniprotkb:DDB1- and CUL4-associated factor 3(gene name synonym)|uniprotkb:KIAA1736(gene name synonym)	psi-mi:ddl_yerpe(display_long)|uniprotkb:ddl(gene name)|psi-mi:ddl(display_short)|uniprotkb:ddlB(gene name synonym)|uniprotkb:D-Ala-D-Ala ligase(gene name synonym)|uniprotkb:D-alanylalanine synthetase(gene name synonym)|uniprotkb:YPO0557(locus name)|uniprotkb:y3624(locus name)|uniprotkb:YP_3627(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876171|imex:IM-13779-8367	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110497.15(gene)|ensembl:ENST00000458649.6(transcript)|ensembl:ENST00000683756.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000423""(mitophagy)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005776""(autophagosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0005930""(axoneme)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021915""(neural tube development)|go:""GO:0030154""(cell differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045591""(positive regulation of regulatory T cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051020""(GTPase binding)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|go:""GO:0098780""(response to mitochondrial depolarisation)|go:""GO:1901526""(positive regulation of mitophagy)|go:""GO:1904544""(positive regulation of free ubiquitin chain polymerization)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR052596|mint:Q9C0C7|rcsb pdb:8WQR|reactome:R-HSA-1632852|refseq:NP_060219.2|refseq:NP_001254711.1|refseq:NP_001254712.1|refseq:XP_005253066.1|refseq:XP_005253068.1|refseq:XP_005253071.1|refseq:XP_006718322.1|refseq:NP_001287660.1|dip:DIP-53597N|panther:PTHR22874(orthology-group)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR000291(D-alanine--D-alanine ligase/VANA/B/C, conserved site)|interpro:IPR005905(D-alanine--D-alanine ligase)|interpro:IPR011095(D-alanine--D-alanine ligase, C-terminal)|interpro:IPR011127(D-alanine--D-alanine ligase, N-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:5BPF|rcsb pdb:5BPH|rcsb pdb:5C1O|rcsb pdb:5C1P|rcsb pdb:3V4Z|refseq:WP_002210432.1|rcsb pdb:4ZQI|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008716""(D-alanine-D-alanine ligase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0071555""(cell wall organization)|refseq:YP_002345628.1|panther:PTHR23132(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:h4yD2iL711peDzI4kttngSdTLQk9606	rogid:NMpRC51zhBG97/cvKC75+fOPDQY632	intact-crc:B43E5CD74FF9D1AE|rigid:Qn+rlBDKD8vbe7oQsD1dGpBSJu8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CK83	uniprotkb:Q9ULX6	intact:EBI-2851851|uniprotkb:Q74QS6	intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557.3	psi-mi:q8ck83_yerpe(display_long)|uniprotkb:accC1(gene name)|psi-mi:accC1(display_short)|uniprotkb:YP_3384(locus name)|uniprotkb:y4042(locus name)	psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876211|imex:IM-13779-8374	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|go:""GO:0005524""(ATP binding)|go:""GO:0016874""(ligase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR052032"	"refseq:NP_001278407.1|refseq:NP_055186.3|ensembl:ENSG00000011243.19(gene)|ensembl:ENST00000397410.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005521""(lamin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0007076""(mitotic chromosome condensation)|go:""GO:0008380""(RNA splicing)|go:""GO:0010793""(regulation of mRNA export from nucleus)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016605""(PML body)|go:""GO:0016607""(nuclear speck)|go:""GO:0017151""(DEAD/H-box RNA helicase binding)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044839""(cell cycle G2/M phase transition)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051081""(nuclear membrane disassembly)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR007071(""A-kinase anchoring protein 95 (AKAP95)"")|interpro:IPR034736|mint:Q9ULX6|reactome:R-HSA-9772755|dip:DIP-27541N|panther:PTHR12190(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zWNetqBcgNgoffpGm1WuBpGKZiA632	rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606	intact-crc:6CBA857C846454DE|rigid:CjYyg3ZO7iYDZ6PhWVtH2Add/fo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZT6	uniprotkb:P14550	intact:EBI-2863462	intact:EBI-372388|ensembl:ENSP00000312606.4|ensembl:ENSP00000361140.3|ensembl:ENSP00000480713.1|uniprotkb:A8KAL8|uniprotkb:Q6IAZ4|uniprotkb:D3DQ04	psi-mi:q8czt6_yerpe(display_long)|uniprotkb:y3428(locus name)	"psi-mi:ak1a1_human(display_long)|uniprotkb:Aldehyde reductase(gene name synonym)|uniprotkb:AKR1A1(gene name)|psi-mi:AKR1A1(display_short)|uniprotkb:ALDR1(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:""Alcohol dehydrogenase [NADP(+)]""(gene name synonym)|uniprotkb:Glucuronate reductase(gene name synonym)|uniprotkb:Glucuronolactone reductase(gene name synonym)|uniprotkb:S-nitroso-CoA reductase(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876225|imex:IM-13779-8373	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|interpro:IPR051551|go:""GO:0019867""(outer membrane)|interpro:IPR043990"	"ensembl:ENSG00000117448.14(gene)|ensembl:ENST00000351829.9(transcript)|ensembl:ENST00000372070.7(transcript)|ensembl:ENST00000621846.4(transcript)|go:""GO:0004032""(""aldose reductase (NADPH) activity"")|go:""GO:0004033""(""aldo-keto reductase (NADPH) activity"")|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019640""(D-glucuronate catabolic process to D-xylulose 5-phosphate)|go:""GO:0019853""(L-ascorbic acid biosynthetic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044597""(daunorubicin metabolic process)|go:""GO:0044598""(doxorubicin metabolic process)|go:""GO:0045202""(synapse)|go:""GO:0046185""(aldehyde catabolic process)|go:""GO:0047655""(allyl-alcohol dehydrogenase activity)|go:""GO:0047939""(L-glucuronate reductase activity)|go:""GO:0047941""(glucuronolactone reductase activity)|go:""GO:0047956""(""glycerol dehydrogenase (NADP+) activity"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0080007""(""S-nitrosoglutathione reductase (NADH) activity"")|go:""GO:0110095""(cellular detoxification of aldehyde)|go:""GO:0160163""(""S-nitrosoglutathione reductase (NADPH) activity"")|go:""GO:1901687""(glutathione derivative biosynthetic process)|go:""GO:1990002""(""methylglyoxal reductase (NADPH) (acetol producing) activity"")|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|interpro:IPR044481|mint:P14550|rcsb pdb:2ALR|reactome:R-HSA-156590|reactome:R-HSA-5661270|refseq:NP_001189342.1|refseq:NP_001189343.1|refseq:NP_006057.1|refseq:NP_697021.1|panther:PTHR11732(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MiLa9vLiNmbmMr4denBvKhQstG8632	rogid:MWIly3lvCgExPs2LWAgQCeYe3aw9606	intact-crc:F864CB1CED16FDAE|rigid:JXKF9BW2613JfAw5Ac1P8QXwyz0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WYP5	uniprotkb:Q8D0N9	intact:EBI-396018|uniprotkb:Q7Z4E3|uniprotkb:Q8IZA4|uniprotkb:Q96EH9|uniprotkb:Q9Y4Q6|uniprotkb:A6NGM0|uniprotkb:A8MSG9|uniprotkb:A8MZ86|ensembl:ENSP00000497061.2	intact:EBI-2845331|uniprotkb:Q74UJ0	psi-mi:elys_human(display_long)|uniprotkb:Protein MEL-28(gene name synonym)|uniprotkb:Putative AT-hook-containing transcription factor 1(gene name synonym)|uniprotkb:AHCTF1(gene name)|psi-mi:AHCTF1(display_short)|uniprotkb:Embryonic large molecule derived from yolk sac(gene name synonym)|uniprotkb:ELYS(gene name synonym)|uniprotkb:TMBS62(gene name synonym)|uniprotkb:MSTP108(orf name)	psi-mi:q8d0n9_yerpe(display_long)|uniprotkb:pqiB2(gene name)|psi-mi:pqiB2(display_short)|uniprotkb:YP_1726(locus name)|uniprotkb:y1863(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876232|imex:IM-13779-8375	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056261.4|refseq:XP_006711821.1|refseq:NP_001310271.1|ensembl:ENSG00000153207.16(gene)|ensembl:ENST00000648844.2(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0015031""(protein transport)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016604""(nuclear body)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0051028""(mRNA transport)|go:""GO:0051292""(nuclear pore complex assembly)|go:""GO:0051301""(cell division)|go:""GO:0070062""(extracellular exosome)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR025151|interpro:IPR032040|interpro:IPR052620|mint:Q8WYP5|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|panther:PTHR21583(orthology-group)"	"interpro:IPR003399(Mammalian cell entry related)|go:""GO:0016020""(membrane)|interpro:IPR051800"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ydOhjwcpt7Vl1X/urbAgH7EQrtE9606	rogid:ubTQpOsKz5MxAzZCDHdFKkWSofo632	intact-crc:9D00763BCC79365E|rigid:QO5e0tWVDlCQtKuskgOIphnmifg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12802	uniprotkb:Q8D0D4	intact:EBI-1373806|uniprotkb:Q14572|uniprotkb:Q59FP6|uniprotkb:Q86W90|uniprotkb:Q8WXQ6|uniprotkb:Q96JP6|uniprotkb:Q96P79|uniprotkb:Q9Y5T0|uniprotkb:Q9Y5T6|ensembl:ENSP00000378026.3|intact:EBI-28978093	intact:EBI-2847212	psi-mi:akp13_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 13(gene name synonym)|uniprotkb:Breast cancer nuclear receptor-binding auxiliary protein(gene name synonym)|uniprotkb:Human thyroid-anchoring protein 31(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor Lbc(gene name synonym)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:Lymphoid blast crisis oncogene(gene name synonym)|uniprotkb:Non-oncogenic Rho GTPase-specific GTP exchange factor(gene name synonym)|uniprotkb:AKAP13(gene name)|psi-mi:AKAP13(display_short)|uniprotkb:BRX(gene name synonym)|uniprotkb:HT31(gene name synonym)|uniprotkb:LBC(gene name synonym)	psi-mi:q8d0d4_yerpe(display_long)|uniprotkb:hmsH(gene name)|psi-mi:hmsH(display_short)|uniprotkb:y2359(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876218|imex:IM-13779-8372	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006729.4|refseq:NP_009131.2|refseq:NP_001257475.1|ensembl:ENSG00000170776.22(gene)|ensembl:ENST00000394518.7(transcript)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007507""(heart development)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0046872""(metal ion binding)|go:""GO:0051018""(protein kinase A binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060297""(regulation of sarcomere organization)|go:""GO:0060348""(bone development)|go:""GO:0071875""(adrenergic receptor signaling pathway)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018459|interpro:IPR035899|interpro:IPR041020|interpro:IPR046349|interpro:IPR051632|mint:Q12802|rcsb pdb:2DRN|rcsb pdb:2LG1|rcsb pdb:4D0N|rcsb pdb:4D0O|rcsb pdb:6BCA|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|dip:DIP-180N|panther:PTHR13944(orthology-group)"	"interpro:IPR023870|interpro:IPR011990(Tetratricopeptide-like helical)|go:""GO:1901515""(poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity)|interpro:IPR049003"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pHHpKUh10J/O/fp06k4NaNhJF6U9606	rogid:oBs/IRM9/gKecuXNw9IoCZLu4Vw632	intact-crc:BDA3D7356714D452|rigid:95Cy9+GfXYqxF0wcF7MqMhFbn6k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5TGY3	uniprotkb:Q8ZHG8	intact:EBI-948813|uniprotkb:Q5TGY4|uniprotkb:Q6PJK1|uniprotkb:Q6ZUQ6|uniprotkb:Q99769|uniprotkb:Q9NUF5|ensembl:ENSP00000247087.4|ensembl:ENSP00000363123.2|ensembl:ENSP00000494394.1|ensembl:ENSP00000495072.1|ensembl:ENSP00000495665.1|ensembl:ENSP00000501218.1	intact:EBI-2849252|uniprotkb:Q0WIB1	psi-mi:ahdc1_human(display_long)|uniprotkb:AHDC1(gene name)|psi-mi:AHDC1(display_short)|uniprotkb:AT-hook DNA-binding motif-containing protein 1(gene name synonym)	psi-mi:spea_yerpe(display_long)|uniprotkb:speA(gene name)|psi-mi:speA(display_short)|uniprotkb:YPO0929(locus name)|uniprotkb:y3313(locus name)|uniprotkb:YP_3513(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876253|imex:IM-13779-8379	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:412069""|ensembl:ENSG00000126705.15(gene)|ensembl:ENST00000247087.10(transcript)|ensembl:ENST00000374011.6(transcript)|ensembl:ENST00000642245.1(transcript)|ensembl:ENST00000642416.1(transcript)|ensembl:ENST00000644989.1(transcript)|ensembl:ENST00000673934.1(transcript)|go:""GO:0001707""(mesoderm formation)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0030154""(cell differentiation)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0140585""(promoter-enhancer loop anchoring activity)|interpro:IPR032757|interpro:IPR039225|mint:Q5TGY3|refseq:NP_001025053.1|refseq:XP_005245905.1|refseq:XP_005245906.1|refseq:XP_005245907.1|refseq:XP_005245908.1|refseq:XP_005245909.1|refseq:XP_011539557.1|refseq:XP_011539558.1|refseq:XP_011539559.1|panther:PTHR15617(orthology-group)"	"interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR002985(Arginine decarboxylase)|interpro:IPR022657|interpro:IPR022644|interpro:IPR022653|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|interpro:IPR029066|interpro:IPR040634|go:""GO:0006527""(arginine catabolic process)|go:""GO:0008295""(spermidine biosynthetic process)|go:""GO:0008792""(arginine decarboxylase activity)|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0046872""(metal ion binding)|interpro:IPR041128|refseq:WP_002209969.1|refseq:YP_002345977.1|panther:PTHR43295(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lYUJEAEhxO204mZnqOd4Vf6K/g89606	rogid:WJK/NuC1y1WJhbzgBDwly+QaYwA632	intact-crc:F6C69C008AA1BC50|rigid:J74TNF54EuKL5mEUScQK8jl4/GI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q09666	uniprotkb:A0A454XXH7	intact:EBI-2555881|uniprotkb:A1A586|ensembl:ENSP00000367263.4	intact:EBI-2851240|uniprotkb:Q74Y15|uniprotkb:A0A0H2W158|uniprotkb:Q7CFV5|uniprotkb:A0A384K924	psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short)	psi-mi:a0a454xxh7_yerpe(display_long)|uniprotkb:YPO0168(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876246|imex:IM-13779-8376	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001611.1|refseq:NP_076965.2|refseq:NP_001333374.1|refseq:NP_001333375.1|ensembl:ENSG00000124942.14(gene)|ensembl:ENST00000378024.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0030315""(T-tubule)|go:""GO:0031982""(vesicle)|go:""GO:0042383""(sarcolemma)|go:""GO:0042802""(identical protein binding)|go:""GO:0043034""(costamere)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097493""(structural molecule activity conferring elasticity)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:1901385""(regulation of voltage-gated calcium channel activity)|go:""GO:1905686""(positive regulation of plasma membrane repair)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR052082|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|panther:PTHR23348(orthology-group)"	interpro:IPR027417|refseq:WP_002215686.1|interpro:IPR033186|refseq:YP_002345254.1|interpro:IPR051162|panther:PTHR30121(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:u1oecAyIihgxzfTz0jholE8wksA9606	rogid:7T8Io5VjMpoAGWF393x9GYtAK2w632	intact-crc:65E3D4CC141EAF23|rigid:+O6eRKpp4QWrkmx6BqKDOoFVv7M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35869	uniprotkb:Q8ZD12	intact:EBI-80780|uniprotkb:A4D130|uniprotkb:Q13728|uniprotkb:Q13803|uniprotkb:Q13804|ensembl:ENSP00000242057.4|ensembl:ENSP00000436466.1	intact:EBI-2847057|uniprotkb:Q0WDB0	psi-mi:ahr_human(display_long)|uniprotkb:AHR(gene name)|psi-mi:AHR(display_short)|uniprotkb:BHLHE76(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 76(gene name synonym)	psi-mi:y2781_yerpe(display_long)|uniprotkb:YPO2781(locus name)|uniprotkb:y1614(locus name)|uniprotkb:YP_2383(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876239|imex:IM-13779-8380	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106546.14(gene)|ensembl:ENST00000242057.9(transcript)|ensembl:ENST00000463496.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001094""(TFIID-class transcription factor complex binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001568""(blood vessel development)|go:""GO:0002819""(regulation of adaptive immune response)|go:""GO:0002841""(negative regulation of T cell mediated immune response to tumor cell)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0004879""(nuclear receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0017025""(TBP-class protein binding)|go:""GO:0030888""(regulation of B cell proliferation)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034751""(aryl hydrocarbon receptor complex)|go:""GO:0034752""(cytosolic aryl hydrocarbon receptor complex)|go:""GO:0034753""(nuclear aryl hydrocarbon receptor complex)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070888""(E-box binding)|go:""GO:0071219""(cellular response to molecule of bacterial origin)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:1904322""(cellular response to forskolin)|go:""GO:1904613""(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:5NJ8|rcsb pdb:7ZUB|rcsb pdb:8QMO|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|refseq:NP_001612.1|panther:PTHR10649(orthology-group)|efo:""Orphanet:791""|dip:DIP-946N"	"interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR024195|refseq:WP_002209742.1|go:""GO:0005737""(cytoplasm)|go:""GO:0016818""(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347728.1|panther:PTHR43758(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7hBqGKPH2nBDWpy9UoQ7+KpY+ic9606	rogid:+djMSbEwT6HdcEtL19C6UCvdH70632	intact-crc:F40A7097E1FBEB73|rigid:zQHhlGdkQFZhDB149TIwKaMNMPk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H077	uniprotkb:Q6ULP2	intact:EBI-2841812|uniprotkb:Q74VJ9|uniprotkb:A0A384LD89|uniprotkb:Q0WHC7|uniprotkb:Q7CHD8|uniprotkb:A0A380PPP8	intact:EBI-2848714|uniprotkb:Q9HAB9|uniprotkb:Q86VW3|uniprotkb:Q9NXS4|uniprotkb:Q8TCF3|uniprotkb:Q9H7E3|uniprotkb:Q6ZM66|uniprotkb:D6W5E9|intact:EBI-10988158|intact:EBI-28972107|ensembl:ENSP00000387071.1	psi-mi:a0a2u2h077_yerpe(display_long)|uniprotkb:mtr(gene name)|psi-mi:mtr(display_short)|uniprotkb:YPO1285(locus name)	psi-mi:aftin_human(display_long)|uniprotkb:AFTPH(gene name)|psi-mi:AFTPH(display_short)|uniprotkb:AFTH(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876267|imex:IM-13779-8378	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018227|interpro:IPR013059(Tryptophan/tyrosine transporter)|interpro:IPR006311(Twin-arginine translocation pathway signal)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005886""(plasma membrane)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|refseq:YP_002346311.1|refseq:WP_002208812.1"	"refseq:XP_005264437.1|refseq:NP_001002243.1|refseq:NP_060127.3|refseq:NP_982261.2|ensembl:ENSG00000119844.17(gene)|ensembl:ENST00000409933.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0015031""(protein transport)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR029205|interpro:IPR046359|mint:Q6ULP2|panther:PTHR16156(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M4JTYX328BR2JznjfkTVzEKmmW4632	rogid:g/Z0njIYzzLZeiidOKVtPRUKnso9606	intact-crc:67BC4B2A49A1D795|rigid:2aeNAiGKE27bcK0MxK/7vwQvwy4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ULP2	uniprotkb:A0A3N4B631	intact:EBI-2848714|uniprotkb:Q9HAB9|uniprotkb:Q86VW3|uniprotkb:Q9NXS4|uniprotkb:Q8TCF3|uniprotkb:Q9H7E3|uniprotkb:Q6ZM66|uniprotkb:D6W5E9|intact:EBI-10988158|intact:EBI-28972107|ensembl:ENSP00000387071.1	intact:EBI-2859968|uniprotkb:Q74VK7|uniprotkb:Q0WHB8|uniprotkb:Q7CHE6	psi-mi:aftin_human(display_long)|uniprotkb:AFTPH(gene name)|psi-mi:AFTPH(display_short)|uniprotkb:AFTH(gene name synonym)	psi-mi:a0a3n4b631_yerpe(display_long)|uniprotkb:YPO1294(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876260|imex:IM-13779-8377	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005264437.1|refseq:NP_001002243.1|refseq:NP_060127.3|refseq:NP_982261.2|ensembl:ENSG00000119844.17(gene)|ensembl:ENST00000409933.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0015031""(protein transport)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR029205|interpro:IPR046359|mint:Q6ULP2|panther:PTHR16156(orthology-group)"	"refseq:YP_002346320.1|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR050107|refseq:WP_002208803.1|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|panther:PTHR43790(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:g/Z0njIYzzLZeiidOKVtPRUKnso9606	rogid:0VaVASVo0mvyDl5gKVp5uAy75QI632	intact-crc:7FE84AF6CCFD2C26|rigid:7uQ+ZVf9REdvdowP03jUjMLoUnI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D080	uniprotkb:Q08117	intact:EBI-2841341	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	psi-mi:q8d080_yerpe(display_long)|uniprotkb:y2613(locus name)	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876288|imex:IM-13779-8382	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001670(Iron-containing alcohol dehydrogenase)|interpro:IPR018211|go:""GO:0016614""(oxidoreductase activity, acting on CH-OH group of donors)|go:""GO:0046872""(metal ion binding)|interpro:IPR016205(Glycerol dehydrogenase)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lUUIJTo0TaVgDeJFI9qxAhwSaLs632	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	intact-crc:687A751242BB9F1D|rigid:PNRwjddUzhR/gsVR/T05Vul0Jls	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GVV5	uniprotkb:P51825	intact:EBI-2848661|uniprotkb:Q0WGP6|uniprotkb:Q7CHR3|uniprotkb:A0A384LCC2	intact:EBI-2610180|intact:EBI-28974592|ensembl:ENSP00000305689.6|uniprotkb:B4DTU1|uniprotkb:E9PBM3|intact:EBI-11028221	psi-mi:a0a2u2gvv5_yerpe(display_long)|uniprotkb:YPO1526(locus name)	psi-mi:aff1_human(display_long)|uniprotkb:AFF1(gene name)|psi-mi:AFF1(display_short)|uniprotkb:AF4(gene name synonym)|uniprotkb:FEL(gene name synonym)|uniprotkb:MLLT2(gene name synonym)|uniprotkb:PBM1(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 4 protein(gene name synonym)|uniprotkb:Proto-oncogene AF4(gene name synonym)|uniprotkb:Protein FEL(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876274|imex:IM-13779-8381	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR032712|interpro:IPR007844(AsmA)|refseq:WP_002211874.1|go:""GO:0005886""(plasma membrane)|go:""GO:0090313""(regulation of protein targeting to membrane)|refseq:YP_002346542.1|interpro:IPR052894|panther:PTHR30441(orthology-group)"	"ensembl:ENSG00000172493.23(gene)|ensembl:ENST00000307808.10(transcript)|go:""GO:0008023""(transcription elongation factor complex)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0032783""(super elongation complex)|interpro:IPR007797(AF-4 proto-oncoprotein)|interpro:IPR043639|interpro:IPR043640|mint:P51825|rcsb pdb:2LM0|refseq:NP_001160165.1|refseq:NP_001300888.1|refseq:NP_001300889.1|refseq:NP_005926.1|refseq:XP_005263064.1|refseq:XP_011530275.1|dip:DIP-56407N|efo:""Orphanet:589595""|panther:PTHR10528(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/31	rogid:FFiHcUgeYNIDG2pyac5+94Afrxg632	rogid:dfXWN9v1lQ9Tz77hzdYOBy7xn1Q9606	intact-crc:65C6AD764EF3FCC3|rigid:bff4Da/IwP6ef2Iou8Yd4gfob40	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZZ7	uniprotkb:Q08117	intact:EBI-2842831|uniprotkb:Q74W48	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	psi-mi:q8czz7_yerpe(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:YP_1051(locus name)|uniprotkb:y3075(locus name)	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876302|imex:IM-13779-8385	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5D57QZRbHjtu2izZZ+54f7spmuk632	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	intact-crc:9FE74D45433AF033|rigid:VpHDW07Uol4WIGcs+eLM5XqytB4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D068	uniprotkb:Q08117	intact:EBI-2846153|uniprotkb:Q74VD0	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	psi-mi:q8d068_yerpe(display_long)|uniprotkb:uup3(gene name)|psi-mi:uup3(display_short)|uniprotkb:YP_1381(locus name)|uniprotkb:y2677(locus name)	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876295|imex:IM-13779-8383	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR032781|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR050611"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uq/st091dJjwV1JggBt3SaIlbSQ632	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	intact-crc:14D47512405F492E|rigid:YfqqaMDcPfc4eVKZVp6An4L+260	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Z373	uniprotkb:Q08117	intact:EBI-2852777|uniprotkb:Q7CI40|uniprotkb:A0A3N4BFY5|uniprotkb:A0A380PDJ9	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	psi-mi:q9z373_yerpe(display_long)|uniprotkb:irp1(gene name)|psi-mi:irp1(display_short)|uniprotkb:YPO1910(locus name)	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876281|imex:IM-13779-8384	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050091|interpro:IPR029058|interpro:IPR029063|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR001242(Condensation domain)|interpro:IPR018201|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR001031(Thioesterase)|interpro:IPR016039(Thiolase-like)|interpro:IPR032821|interpro:IPR013968(Polyketide synthase, KR)|refseq:WP_002212777.1|interpro:IPR020802|interpro:IPR020806|interpro:IPR020841|go:""GO:0004312""(fatty acid synthase activity)|go:""GO:0004315""(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0009403""(toxin biosynthetic process)|go:""GO:0031177""(phosphopantetheine binding)|go:""GO:0071770""(DIM/DIP cell wall layer assembly)|interpro:IPR001227(Acyl transferase region)|interpro:IPR023213|interpro:IPR036291|interpro:IPR036736|refseq:YP_002346901.1|panther:PTHR43775(orthology-group)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VcII888G29brUUb5IumAuWSgrE4632	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	intact-crc:C2D7C571335DEF72|rigid:D9Xu6RiKOwd2zGqqRJJ9gER614w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08117	uniprotkb:O68769	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	intact:EBI-2845621|uniprotkb:A0A384LBJ7|uniprotkb:Q74YJ8|uniprotkb:Q7ARC7|uniprotkb:Q7BT03|uniprotkb:A0A3G5LHP7|uniprotkb:A0A1U8QJV7|uniprotkb:A0A2U2H212	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:o68769_yerpe(display_long)|uniprotkb:YPMT1.55c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876330|imex:IM-13779-8387	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"refseq:NP_395400.1|refseq:YP_093945.1|refseq:NP_857688.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|refseq:WP_002213143.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:nQbvf/FMyfPAI9dWsYFXKmJ70HI632	intact-crc:99D072431DBDB7D0|rigid:wOqWbYAZRTNB9dUpBpa34D/Xsgc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZU9	uniprotkb:Q08117	intact:EBI-2841714	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	psi-mi:q8czu9_yerpe(display_long)|uniprotkb:y3342(locus name)	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876309|imex:IM-13779-8389	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR002491(Periplasmic binding protein)|interpro:IPR050902	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:61Vn/X9ZzrY6cGaSgyM0HeClZVc632	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	intact-crc:98384D45401479E8|rigid:7ewNX6mGcXzlOc+41o8WOMUSKAM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLQ8	uniprotkb:Q08117	intact:EBI-2873342	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	psi-mi:q8clq8_yerpe(display_long)|uniprotkb:y0552(locus name)	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876316|imex:IM-13779-8386	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR024197|interpro:IPR036412|go:""GO:0046872""(metal ion binding)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Qz/RmtxarSMQb5ce+N3MH7NAenY632	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	intact-crc:C3E47B454049F169|rigid:y6i2kKpycTWInm8Fx66gaHv8ukw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YGL8	uniprotkb:Q08117	intact:EBI-2845909|uniprotkb:Q74VS1|uniprotkb:Q0WH41|uniprotkb:Q7CHI6|uniprotkb:A0A384L3E0	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	psi-mi:a0a5p8ygl8_yerpe(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:YPO1374(locus name)	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876323|imex:IM-13779-8388	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0019430""(removal of superoxide radicals)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_002211341.1|interpro:IPR036188|refseq:YP_002346397.1|interpro:IPR050097|panther:PTHR48105(orthology-group)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lNjtMW37Ur6Z7pzA6LzMVzq9VCU632	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	intact-crc:6877373982A74790|rigid:peWta0+O3Nza/nfNGNAY0bAO7W8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08117	uniprotkb:A0A2U2H1V8	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	intact:EBI-2842206|uniprotkb:O68762|uniprotkb:Q74YK8|uniprotkb:A0A384KZR0|uniprotkb:A0A1U8QG56|uniprotkb:A0A0H2W1K6|uniprotkb:Q7ARD1	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:a0a2u2h1v8_yerpe(display_long)|uniprotkb:YPMT1.47c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876337|imex:IM-13779-8390	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"refseq:NP_395390.1|refseq:YP_093935.1|refseq:WP_002222869.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:HfbjH2+V5FcTdJjdFEwPlsVE9ek632	intact-crc:9E24BD20111F1E23|rigid:WEAjrL4ElNIsASQp+lQKMPfyJD8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08117	uniprotkb:Q8ZJJ5	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	intact:EBI-2842956|uniprotkb:Q0WKJ3	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:hslu_yerpe(display_long)|uniprotkb:hslU(gene name)|psi-mi:hslU(display_short)|uniprotkb:Unfoldase HslU(gene name synonym)|uniprotkb:YPO0105(locus name)|uniprotkb:y0294(locus name)|uniprotkb:YP_0107(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876344|imex:IM-13779-8391	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR004491(Heat shock protein HslU)|interpro:IPR027417|go:""GO:0008233""(peptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0009376""(HslUV protease complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043335""(protein unfolding)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|refseq:WP_002208943.1|refseq:YP_002345195.1|interpro:IPR050052|panther:PTHR48102(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:9NL3dzNGgq2JqZd7+stwnNgbDk0632	intact-crc:007BBCAC4386C4FE|rigid:mtLZHgP6WGa1vUmOshSgSJ1TMyY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BRR6	uniprotkb:Q8ZIF7	intact:EBI-723761|uniprotkb:Q49AU7|uniprotkb:Q8NBI1|uniprotkb:Q8WZ90|uniprotkb:Q96NF8|uniprotkb:Q9H0A7|ensembl:ENSP00000397694.3	intact:EBI-2876354|uniprotkb:Q0WJC0	psi-mi:adpgk_human(display_long)|uniprotkb:RbBP-35(gene name synonym)|uniprotkb:ADPGK(gene name)|psi-mi:ADPGK(display_short)|uniprotkb:PSEC0260(orf name)	"psi-mi:rsmh_yerpe(display_long)|uniprotkb:rsmH(gene name)|psi-mi:rsmH(display_short)|uniprotkb:mraW(gene name synonym)|uniprotkb:""16S rRNA m(4)C1402 methyltransferase""(gene name synonym)|uniprotkb:""rRNA (cytosine-N(4)-)-methyltransferase RsmH""(gene name synonym)|uniprotkb:YPO0547(locus name)|uniprotkb:y3634(locus name)|uniprotkb:YP_3637(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876351|imex:IM-13779-8393	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_112574.3|refseq:XP_006720775.1|ensembl:ENSG00000159322.18(gene)|ensembl:ENST00000456471.3(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0043843""(ADP-specific glucokinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0061620""(glycolytic process through glucose-6-phosphate)|interpro:IPR007666(ADP-specific phosphofructokinase/glucokinase)|interpro:IPR029056|mint:Q9BRR6|reactome:R-HSA-70171|panther:PTHR21208(orthology-group)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0070475""(rRNA base methylation)|go:""GO:0071424""(""rRNA (cytosine-N4-)-methyltransferase activity"")|interpro:IPR002903(Bacterial methyltransferase)|interpro:IPR023397|interpro:IPR029063|refseq:WP_002210442.1|refseq:YP_002345618.1|panther:PTHR11265(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jeRKymflPO3JABiI6J42cZZEbwc9606	rogid:OGgbezdpTIhwZTTf5sTpYdun8CY632	intact-crc:145E2CDEC14E1A98|rigid:Qi2B7MV7oXi1cVWuzksDtw3Y7bo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG0	uniprotkb:Q6IQ32	intact:EBI-2842527|uniprotkb:Q8CKL4|uniprotkb:Q0WIA2|uniprotkb:Q74QH2	intact:EBI-2838654|uniprotkb:A8K951|uniprotkb:Q9H9P3|uniprotkb:O94943|ensembl:ENSP00000262198.3	psi-mi:agua_yerpe(display_long)|uniprotkb:aguA(gene name)|psi-mi:aguA(display_short)|uniprotkb:Agmatine iminohydrolase(gene name synonym)|uniprotkb:YPO0939(locus name)|uniprotkb:y3325(locus name)|uniprotkb:YP_3503(locus name)	psi-mi:adnp2_human(display_long)|uniprotkb:ADNP2(gene name)|psi-mi:ADNP2(display_short)|uniprotkb:KIAA0863(gene name synonym)|uniprotkb:ZNF508(gene name synonym)|uniprotkb:Zinc finger protein 508(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876363|imex:IM-13779-8394	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017754(Agmatine deiminase)|interpro:IPR007466(Peptidyl-arginine deiminase, Porphyromonas-type)|go:""GO:0004668""(protein-arginine deiminase activity)|go:""GO:0009446""(putrescine biosynthetic process)|go:""GO:0047632""(agmatine deiminase activity)|refseq:YP_002345986.1|panther:PTHR31377(orthology-group)"	"refseq:NP_055728.1|ensembl:ENSG00000101544.9(gene)|ensembl:ENST00000262198.9(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0007399""(nervous system development)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0046872""(metal ion binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|interpro:IPR045762|mint:Q6IQ32|refseq:XP_005266713.1|panther:PTHR15740(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wqVmguxc+OwAcDUbyMd1UcCWH/o632	rogid:yzYCNBnFFszXO4X7vp01+DcaGvs9606	intact-crc:8B6F3FB2FE8D7DA3|rigid:JYyMngDKqbC8JOXNbzy5mACxdLY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAA1	uniprotkb:P55263	intact:EBI-2860122|uniprotkb:Q74RC5|uniprotkb:Q8D1L7|uniprotkb:Q0WAA3	intact:EBI-1384340|uniprotkb:B7Z800|uniprotkb:O00741|uniprotkb:O00742|uniprotkb:Q16710|uniprotkb:Q9BTN2|uniprotkb:Q5JQ11|ensembl:ENSP00000443965.2|uniprotkb:B7Z783|uniprotkb:Q5JQ10	psi-mi:btub_yerpe(display_long)|uniprotkb:btuB(gene name)|psi-mi:btuB(display_short)|uniprotkb:Cobalamin receptor(gene name synonym)|uniprotkb:Outer membrane cobalamin translocator(gene name synonym)|uniprotkb:YPO3910(locus name)|uniprotkb:y0325(locus name)|uniprotkb:YP_3138(locus name)	psi-mi:adk_human(display_long)|uniprotkb:Adenosine 5'-phosphotransferase(gene name synonym)|uniprotkb:ADK(gene name)|psi-mi:ADK(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876370|imex:IM-13779-8392	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010101(TonB-dependent vitamin B12 receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR039426|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0015420""(ABC-type vitamin B12 transporter activity)|go:""GO:0015889""(cobalamin transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0046930""(pore complex)|interpro:IPR036942|interpro:IPR037066|refseq:WP_002228170.1|panther:PTHR30069(orthology-group)"	"interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR029056|mint:P55263|rcsb pdb:1BX4|rcsb pdb:2I6A|rcsb pdb:2I6B|rcsb pdb:4O1L|reactome:R-HSA-74217|reactome:R-HSA-9755088|ensembl:ENSG00000156110.15(gene)|ensembl:ENST00000539909.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004001""(adenosine kinase activity)|go:""GO:0004136""(deoxyadenosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006144""(purine nucleobase metabolic process)|go:""GO:0006166""(purine ribonucleoside salvage)|go:""GO:0006175""(dATP biosynthetic process)|go:""GO:0009156""(ribonucleoside monophosphate biosynthetic process)|go:""GO:0032263""(GMP salvage)|go:""GO:0044209""(AMP salvage)|go:""GO:0046872""(metal ion binding)|go:""GO:0106383""(dAMP salvage)|interpro:IPR001805(Adenosine kinase)|interpro:IPR002173(Carbohydrate/puine kinase, PfkB, conserved site)|refseq:NP_001114.2|refseq:NP_001189378.1|refseq:NP_001189379.1|refseq:NP_006712.2|panther:PTHR45769(orthology-group)|efo:""Orphanet:289290"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DOy5Ti+yMtG0ogW80Av35K2fKW0632	rogid:YiapVEW3Fq83fwNLkIwwnJxFYzE9606	intact-crc:BD6F68DBD6F60709|rigid:gHhpWv0ckZWGEL4rKnHN2TiV1o8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15204	uniprotkb:Q8CZU2	intact:EBI-2876384|ensembl:ENSP00000256412.4|uniprotkb:B7ZAK5	intact:EBI-2843382	psi-mi:adec1_human(display_long)|uniprotkb:ADAMDEC1(gene name)|psi-mi:ADAMDEC1(display_short)|uniprotkb:A disintegrin and metalloproteinase domain-like protein decysin-1(gene name synonym)	psi-mi:q8czu2_yerpe(display_long)|uniprotkb:yapH(gene name)|psi-mi:yapH(display_short)|uniprotkb:y3396(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876388|imex:IM-13779-8398	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000134028.14(gene)|ensembl:ENST00000256412.8(transcript)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0006955""(immune response)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0008270""(zinc ion binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|refseq:NP_001138744.1|refseq:NP_055294.1|refseq:NP_001138743.1|panther:PTHR11905(orthology-group)"	"interpro:IPR024973|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0019867""(outer membrane)|interpro:IPR036709|interpro:IPR043990|interpro:IPR050909"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TTvsxolGdw3dwiOBDBo8HLSUddY9606	rogid:w2l6qUtIv4INNGQ9HeM84bFptXU632	intact-crc:98031B2D22F899C6|rigid:/P5wsTB1Az5Jmyr5YDRO/4EnKTw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZF9	uniprotkb:P35611	intact:EBI-2845517	intact:EBI-2809187|uniprotkb:Q16156|uniprotkb:Q14729|uniprotkb:A2A3P0|uniprotkb:Q13734|uniprotkb:Q9UJB6|uniprotkb:D3DVR3|uniprotkb:D3DVR4|uniprotkb:D3DVR5|uniprotkb:Q86XM2|ensembl:ENSP00000381197.1|uniprotkb:B4DI79|uniprotkb:A2A3N8|intact:EBI-28966889	psi-mi:q8czf9_yerpe(display_long)|uniprotkb:y4123(locus name)	psi-mi:adda_human(display_long)|uniprotkb:ADD1(gene name)|psi-mi:ADD1(display_short)|uniprotkb:ADDA(gene name synonym)|uniprotkb:Erythrocyte adducin subunit alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876395|imex:IM-13779-8396	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|interpro:IPR035906|interpro:IPR043429"	"refseq:NP_001273574.1|refseq:XP_005247994.1|refseq:NP_001110.2|refseq:NP_054908.2|refseq:NP_054909.2|refseq:NP_789771.1|ensembl:ENSG00000087274.19(gene)|ensembl:ENST00000398129.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016604""(nuclear body)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030507""(spectrin binding)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:1903142""(positive regulation of establishment of endothelial barrier)|go:""GO:1903393""(positive regulation of adherens junction organization)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|interpro:IPR051017|mint:P35611|reactome:R-HSA-264870|reactome:R-HSA-381038|reactome:R-HSA-5223345|refseq:XP_016863193.1|refseq:XP_016863195.1|refseq:XP_016863196.1|refseq:XP_016863197.1|refseq:XP_016863198.1|refseq:XP_016863199.1|panther:PTHR10672(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lTT/EDwWVuu+Fb2mxQH/pcMBusE632	rogid:aXiCTFAzsmSxxV4OAr22SDyjAxI9606	intact-crc:08641B8F3922E525|rigid:BBDXl94ULywWgrQghWjoLCZCmU8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A7Y8RCW6	uniprotkb:Q8NFM4	intact:EBI-2845056|uniprotkb:Q7CKM5|uniprotkb:A0A5P8YBL8|uniprotkb:Q0WJU7	intact:EBI-2838710|uniprotkb:Q96ML7|uniprotkb:B3KV74|uniprotkb:Q17R40|uniprotkb:D3DS75|ensembl:ENSP00000312126.4|ensembl:ENSP00000393177.2|ensembl:ENSP00000452250.2|ensembl:ENSP00000494454.1|ensembl:ENSP00000494977.1|ensembl:ENSP00000495316.1|uniprotkb:Q6ZTM6	psi-mi:a0a7y8rcw6_yerpe(display_long)|uniprotkb:YPO0363(locus name)	psi-mi:adcy4_human(display_long)|uniprotkb:ADCY4(gene name)|psi-mi:ADCY4(display_short)|uniprotkb:ATP pyrophosphate-lyase 4(gene name synonym)|uniprotkb:Adenylate cyclase type IV(gene name synonym)|uniprotkb:Adenylyl cyclase 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876409|imex:IM-13779-8399	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR024393|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR011066(Mechanosensitive ion channel MscS, C-terminal)|interpro:IPR006685(Mechanosensitive ion channel MscS)|interpro:IPR011014(Mechanosensitive ion channel MscS, transmembrane-2)|interpro:IPR006686(Mechanosensitive ion channel MscS, conserved site)|interpro:IPR025692|go:""GO:0005886""(plasma membrane)|go:""GO:0008381""(mechanosensitive monoatomic ion channel activity)|interpro:IPR049142|interpro:IPR049278|interpro:IPR023408|refseq:YP_002345441.1|interpro:IPR052702"	"refseq:NP_001185497.1|refseq:NP_001185521.1|refseq:NP_640340.2|ensembl:ENST00000310677.8(transcript)|ensembl:ENST00000418030.7(transcript)|ensembl:ENSG00000129467.14(gene)|ensembl:ENSG00000284814.1(gene)|ensembl:ENST00000554068.6(transcript)|ensembl:ENST00000642645.1(transcript)|ensembl:ENST00000644961.1(transcript)|ensembl:ENST00000646612.1(transcript)|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006171""(cAMP biosynthetic process)|go:""GO:0007188""(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0030425""(dendrite)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0046872""(metal ion binding)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR009398(Adenylate cyclase-like)|interpro:IPR018297|interpro:IPR029787|interpro:IPR030672|interpro:IPR032628|reactome:R-HSA-163359|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-170660|reactome:R-HSA-170670|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-9856530|panther:PTHR45627(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:z6l0v0GxSQqbhV/esC/hffWqLG8632	rogid:0CFJP4mHM43Nvzkz1g3K4Rc4jeM9606	intact-crc:EBDD173864647A6F|rigid:R93WwOXspUSZj4l8hr6old4hQmo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99541	uniprotkb:A0A5P8YBG5	intact:EBI-2115275|uniprotkb:Q9BSC3|ensembl:ENSP00000276914.2	intact:EBI-2840276|uniprotkb:Q74R47|uniprotkb:Q0WAJ9|uniprotkb:A0A384KR68|uniprotkb:Q7CKW7|uniprotkb:A0A2U2GXT2	psi-mi:plin2_human(display_long)|uniprotkb:PLIN2(gene name)|psi-mi:PLIN2(display_short)|uniprotkb:Adipose differentiation-related protein(gene name synonym)|uniprotkb:ADFP(gene name synonym)|uniprotkb:Adipophilin(gene name synonym)	psi-mi:a0a5p8ybg5_yerpe(display_long)|uniprotkb:ftsS(gene name)|psi-mi:ftsS(display_short)|uniprotkb:ftsX(gene name synonym)|uniprotkb:YPO3812(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876377|imex:IM-13779-8395	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001113.2|panther:PTHR14024(orthology-group)|ensembl:ENSG00000147872.10(gene)|ensembl:ENST00000276914.7(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010890""(positive regulation of triglyceride storage)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0015909""(long-chain fatty acid transport)|go:""GO:0019915""(lipid storage)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:1905691""(lipid droplet disassembly)|interpro:IPR004279(Perilipin)|mint:Q99541|reactome:R-HSA-1989781|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9841922"	"interpro:IPR004513(ABC transporter, FtsX cell division permease)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|go:""GO:0005886""(plasma membrane)|go:""GO:0051301""(cell division)|interpro:IPR040690|refseq:WP_002211505.1|refseq:YP_002348689.1|interpro:IPR047590"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xxkHHSLfFBbPZp9MtlIHVtSI5n49606	rogid:SDuJtWCYjJZjPF8p6X74WTEddjI632	intact-crc:D3D9FCC907E25C58|rigid:Uk5pQn/v7Aulf+jYQ7Ubvx4EY7g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZDA6	uniprotkb:P35611	intact:EBI-2843773|uniprotkb:Q0WDK8	intact:EBI-2809187|uniprotkb:Q16156|uniprotkb:Q14729|uniprotkb:A2A3P0|uniprotkb:Q13734|uniprotkb:Q9UJB6|uniprotkb:D3DVR3|uniprotkb:D3DVR4|uniprotkb:D3DVR5|uniprotkb:Q86XM2|ensembl:ENSP00000381197.1|uniprotkb:B4DI79|uniprotkb:A2A3N8|intact:EBI-28966889	psi-mi:chbg_yerpe(display_long)|uniprotkb:chbG(gene name)|psi-mi:chbG(display_short)|uniprotkb:Chitin disaccharide deacetylase(gene name synonym)|uniprotkb:Chitobiose deacetylase(gene name synonym)|uniprotkb:Chitobiose-6P deacetylase(gene name synonym)|uniprotkb:Chitotriose deacetylase(gene name synonym)|uniprotkb:Chitotriose-6P deacetylase(gene name synonym)|uniprotkb:YPO2682(locus name)|uniprotkb:YP_2484(locus name)|uniprotkb:y1255(locus name)	psi-mi:adda_human(display_long)|uniprotkb:ADD1(gene name)|psi-mi:ADD1(display_short)|uniprotkb:ADDA(gene name synonym)|uniprotkb:Erythrocyte adducin subunit alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876402|imex:IM-13779-8397	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR006879(YdjC-like protein)|interpro:IPR022948|go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0005737""(cytoplasm)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0019213""(deacetylase activity)|go:""GO:0036311""(chitin disaccharide deacetylase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0052777""(diacetylchitobiose catabolic process)|refseq:WP_002212244.1|refseq:YP_002347630.1|panther:PTHR31609(orthology-group)"	"refseq:NP_001273574.1|refseq:XP_005247994.1|refseq:NP_001110.2|refseq:NP_054908.2|refseq:NP_054909.2|refseq:NP_789771.1|ensembl:ENSG00000087274.19(gene)|ensembl:ENST00000398129.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0008290""(F-actin capping protein complex)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016604""(nuclear body)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030507""(spectrin binding)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:1903142""(positive regulation of establishment of endothelial barrier)|go:""GO:1903393""(positive regulation of adherens junction organization)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|interpro:IPR051017|mint:P35611|reactome:R-HSA-264870|reactome:R-HSA-381038|reactome:R-HSA-5223345|refseq:XP_016863193.1|refseq:XP_016863195.1|refseq:XP_016863196.1|refseq:XP_016863197.1|refseq:XP_016863198.1|refseq:XP_016863199.1|panther:PTHR10672(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pYqUZfBmwRlqczCS0iM02q3LMNo632	rogid:aXiCTFAzsmSxxV4OAr22SDyjAxI9606	intact-crc:BB9B44663A527299|rigid:dDNKkfxFLYT/NBq3RqfLu6tBMoM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NI60	uniprotkb:Q8D134	intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739.3	intact:EBI-2857106	psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name)	psi-mi:q8d134_yerpe(display_long)|uniprotkb:y1147(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876416|imex:IM-13779-8404	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:139485""|ensembl:ENSG00000163050.18(gene)|ensembl:ENST00000366777.4(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0016310""(phosphorylation)|go:""GO:0043531""(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034646|interpro:IPR051409|mint:Q8NI60|rcsb pdb:4PED|rcsb pdb:5I35|rcsb pdb:7UDP|rcsb pdb:7UDQ|reactome:R-HSA-2142789|refseq:NP_064632.2|refseq:XP_005273258.1|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_016857341.1|panther:PTHR43851(orthology-group)"	"interpro:IPR029035|interpro:IPR029061|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR030817|go:""GO:0000287""(magnesium ion binding)|go:""GO:0016823""(hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances)|go:""GO:0019310""(inositol catabolic process)|go:""GO:0019752""(carboxylic acid metabolic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|interpro:IPR045229"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606	rogid:Z+Lv+S7FyW7TVAIuZrZ+Sn9Nlys632	intact-crc:4802531B370A48B1|rigid:09pnIULVBRZz23Udj9liKDZy6d4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GX38	uniprotkb:Q8NI60	intact:EBI-2841288|uniprotkb:A0A0H2W637|uniprotkb:Q74SI0|uniprotkb:A0A384LBC5|uniprotkb:Q7CJG2|uniprotkb:A0A380PEL1	intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739.3	psi-mi:a0a2u2gx38_yerpe(display_long)|uniprotkb:YPO2999(locus name)	psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876423|imex:IM-13779-8400	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|refseq:YP_002347923.1|go:""GO:0019898""(extrinsic component of membrane)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0030313""(cell envelope)|go:""GO:1990195""(macrolide transmembrane transporter complex)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|refseq:WP_002208495.1|interpro:IPR030190"	"efo:""Orphanet:139485""|ensembl:ENSG00000163050.18(gene)|ensembl:ENST00000366777.4(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0016301""(kinase activity)|go:""GO:0016310""(phosphorylation)|go:""GO:0043531""(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034646|interpro:IPR051409|mint:Q8NI60|rcsb pdb:4PED|rcsb pdb:5I35|rcsb pdb:7UDP|rcsb pdb:7UDQ|reactome:R-HSA-2142789|refseq:NP_064632.2|refseq:XP_005273258.1|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_016857341.1|panther:PTHR43851(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sdWXUSDDDoa4ne7FHbQ56e9RFP4632	rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606	intact-crc:9B7F9CBB4DE20630|rigid:siLYGSbJZXMJmzjia4a1FzENjv4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14672	uniprotkb:Q8ZAA1	intact:EBI-1536151|uniprotkb:Q10742|uniprotkb:Q92650|ensembl:ENSP00000260408.3|uniprotkb:B4DU28|intact:EBI-40264323	intact:EBI-2860122|uniprotkb:Q74RC5|uniprotkb:Q8D1L7|uniprotkb:Q0WAA3	psi-mi:ada10_human(display_long)|uniprotkb:ADAM10(gene name)|psi-mi:ADAM10(display_short)|uniprotkb:KUZ(gene name synonym)|uniprotkb:MADM(gene name synonym)|uniprotkb:Mammalian disintegrin-metalloprotease(gene name synonym)|uniprotkb:Kuzbanian protein homolog(gene name synonym)|uniprotkb:CDw156(gene name synonym)	psi-mi:btub_yerpe(display_long)|uniprotkb:btuB(gene name)|psi-mi:btuB(display_short)|uniprotkb:Cobalamin receptor(gene name synonym)|uniprotkb:Outer membrane cobalamin translocator(gene name synonym)|uniprotkb:YPO3910(locus name)|uniprotkb:y0325(locus name)|uniprotkb:YP_3138(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876437|imex:IM-13779-8401	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:178307""|ensembl:ENSG00000137845.15(gene)|ensembl:ENST00000260408.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005798""(Golgi-associated vesicle)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008593""(regulation of Notch signaling pathway)|go:""GO:0009986""(cell surface)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010820""(positive regulation of T cell chemotaxis)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016485""(protein processing)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0034332""(adherens junction organization)|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035579""(specific granule membrane)|go:""GO:0038004""(epidermal growth factor receptor ligand maturation)|go:""GO:0042117""(monocyte activation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042987""(amyloid precursor protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0046930""(pore complex)|go:""GO:0046931""(pore complex assembly)|go:""GO:0051089""(constitutive protein ectodomain proteolysis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070573""(metallodipeptidase activity)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090102""(cochlea development)|go:""GO:0097038""(perinuclear endoplasmic reticulum)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097197""(tetraspanin-enriched microdomain)|go:""GO:0098696""(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099173""(postsynapse organization)|go:""GO:0099175""(regulation of postsynapse organization)|go:""GO:0140249""(protein catabolic process at postsynapse)|go:""GO:1901342""(regulation of vasculature development)|go:""GO:1902945""(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR024079|interpro:IPR034025|interpro:IPR036436|interpro:IPR049038|interpro:IPR051489|mint:O14672|rcsb pdb:6BDZ|rcsb pdb:6BE6|rcsb pdb:8ESV|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-177929|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-381426|reactome:R-HSA-3928665|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9013507|reactome:R-HSA-9013700|reactome:R-HSA-977225|refseq:NP_001101.1|dip:DIP-39889N|panther:PTHR45702(orthology-group)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010101(TonB-dependent vitamin B12 receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR039426|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0015420""(ABC-type vitamin B12 transporter activity)|go:""GO:0015889""(cobalamin transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0046930""(pore complex)|interpro:IPR036942|interpro:IPR037066|refseq:WP_002228170.1|panther:PTHR30069(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:oaWIe6XWClYEFZKUARbeLsWRsu49606	rogid:DOy5Ti+yMtG0ogW80Av35K2fKW0632	intact-crc:4BE5081E67A75BE8|rigid:xMPfj79rYGrn9jg9IweHOqineag	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13444	uniprotkb:Q8CWI4	intact:EBI-77818|uniprotkb:Q5SR69|uniprotkb:Q13493|uniprotkb:Q53XQ0|uniprotkb:Q96C78|uniprotkb:B3KQU5|uniprotkb:Q5SR68|uniprotkb:Q6R267|uniprotkb:Q71S61|uniprotkb:Q71S62|uniprotkb:Q71S63|uniprotkb:Q71S64|uniprotkb:Q71S65|uniprotkb:Q71S66|uniprotkb:Q71S67|uniprotkb:Q71S68|uniprotkb:Q71S69|uniprotkb:B4DLB5|uniprotkb:E9PN65|uniprotkb:B4DMH8|uniprotkb:U3KQL5|ensembl:ENSP00000349436.2	intact:EBI-2841215	psi-mi:ada15_human(display_long)|uniprotkb:ADAM15(gene name)|psi-mi:ADAM15(display_short)|uniprotkb:MDC15(gene name synonym)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15(gene name synonym)|uniprotkb:Metalloprotease RGD disintegrin protein(gene name synonym)|uniprotkb:Metargidin(gene name synonym)	psi-mi:q8cwi4_yerpe(display_long)|uniprotkb:kbl(gene name)|psi-mi:kbl(display_short)|uniprotkb:Glycine acetyltransferase(gene name synonym)|uniprotkb:y0081(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876430|imex:IM-13779-8403	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003806.3|refseq:NP_997074.1|refseq:NP_997077.1|refseq:NP_997078.1|refseq:NP_997079.1|refseq:NP_997080.1|refseq:NP_001248394.1|panther:PTHR11905(orthology-group)|refseq:NP_001248393.1|refseq:NP_001248395.1|ensembl:ENSG00000143537.14(gene)|ensembl:ENST00000356955.7(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001953""(negative regulation of cell-matrix adhesion)|go:""GO:0002418""(immune response to tumor cell)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006508""(proteolysis)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008584""(male gonad development)|go:""GO:0009986""(cell surface)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030574""(collagen catabolic process)|go:""GO:0031514""(motile cilium)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0042246""(tissue regeneration)|go:""GO:0045087""(innate immune response)|go:""GO:0046872""(metal ion binding)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0070062""(extracellular exosome)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1904628""(cellular response to phorbol 13-acetate 12-myristate)|go:""GO:1990910""(response to hypobaric hypoxia)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|mint:Q13444|reactome:R-HSA-1474228|reactome:R-HSA-8941237"	"interpro:IPR011282(2-amino-3-ketobutyrate coenzyme A ligase)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0008890""(glycine C-acetyltransferase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0016874""(ligase activity)|go:""GO:0019518""(L-threonine catabolic process to glycine)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR050087"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/06	rogid:wMQLjw9xepknd94XZXdmwnmEwhc9606	rogid:uETD2R/0GvIqPvz6yt39/YuJzJQ632	intact-crc:D0AADC074A4B2C19|rigid:DrB0TSkVMO2USaWvtyxD8CuPt/Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZC32	uniprotkb:P63261	intact:EBI-2852171|uniprotkb:Q0WC91	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000458162.1|ensembl:ENSP00000458435.1|ensembl:ENSP00000459119.2|ensembl:ENSP00000459124.1|ensembl:ENSP00000460464.2|ensembl:ENSP00000460660.2|ensembl:ENSP00000461672.1|ensembl:ENSP00000466346.2|ensembl:ENSP00000477968.1|ensembl:ENSP00000505060.1|ensembl:ENSP00000505193.1|ensembl:ENSP00000505235.1|ensembl:ENSP00000506126.1|ensembl:ENSP00000506201.1|ensembl:ENSP00000506253.1|ensembl:ENSP00000516869.1|ensembl:ENSP00000516870.1|ensembl:ENSP00000516871.1|ensembl:ENSP00000516872.1|ensembl:ENSP00000516873.1|ensembl:ENSP00000516874.1|ensembl:ENSP00000516875.1|ensembl:ENSP00000516876.1|ensembl:ENSP00000516877.1|ensembl:ENSP00000516879.1|ensembl:ENSP00000516881.1|ensembl:ENSP00000516882.1|ensembl:ENSP00000516884.1|ensembl:ENSP00000516886.1|ensembl:ENSP00000516887.1	psi-mi:quea_yerpe(display_long)|uniprotkb:queA(gene name)|psi-mi:queA(display_short)|uniprotkb:Queuosine biosynthesis protein QueA(gene name synonym)|uniprotkb:YPO3192(locus name)|uniprotkb:y0990(locus name)|uniprotkb:YP_0739(locus name)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876444|imex:IM-13779-8402	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003699(Queuosine biosynthesis protein)|refseq:WP_002208673.1|go:""GO:0002099""(tRNA wobble guanine modification)|go:""GO:0005737""(cytoplasm)|go:""GO:0008616""(queuosine biosynthetic process)|go:""GO:0051075""(""S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"")|interpro:IPR036100|interpro:IPR042118|interpro:IPR042119|refseq:YP_002348097.1|panther:PTHR30307(orthology-group)"	"efo:""Orphanet:2995""|efo:""Orphanet:90635""|efo:""Orphanet:98942""|efo:""Orphanet:98944""|ensembl:ENSG00000184009.13(gene)|ensembl:ENSG00000291420.1(gene)|ensembl:ENST00000570382.2(transcript)|ensembl:ENST00000571721.6(transcript)|ensembl:ENST00000573283.7(transcript)|ensembl:ENST00000575087.5(transcript)|ensembl:ENST00000575659.6(transcript)|ensembl:ENST00000575842.5(transcript)|ensembl:ENST00000575994.6(transcript)|ensembl:ENST00000576544.6(transcript)|ensembl:ENST00000615544.5(transcript)|ensembl:ENST00000679480.1(transcript)|ensembl:ENST00000679778.1(transcript)|ensembl:ENST00000680227.1(transcript)|ensembl:ENST00000680727.1(transcript)|ensembl:ENST00000681052.1(transcript)|ensembl:ENST00000681842.1(transcript)|ensembl:ENST00000707466.1(transcript)|ensembl:ENST00000707467.1(transcript)|ensembl:ENST00000707468.1(transcript)|ensembl:ENST00000707469.1(transcript)|ensembl:ENST00000707470.1(transcript)|ensembl:ENST00000707471.1(transcript)|ensembl:ENST00000707472.1(transcript)|ensembl:ENST00000707473.1(transcript)|ensembl:ENST00000707474.1(transcript)|ensembl:ENST00000707479.1(transcript)|ensembl:ENST00000707482.1(transcript)|ensembl:ENST00000707485.1(transcript)|ensembl:ENST00000707487.1(transcript)|ensembl:ENST00000707489.1(transcript)|ensembl:ENST00000707490.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005522""(profilin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007409""(axonogenesis)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030016""(myofibril)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031941""(filamentous actin)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048870""(cell motility)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0120192""(tight junction assembly)|go:""GO:0120220""(basal body patch)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902396""(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7NVM|rcsb pdb:8DNF|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|refseq:NP_001186883.1|refseq:NP_001605.1|panther:PTHR11937(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:F+PRsjhaH3dz6Fk0kbG+UQpfEYY632	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:612A96830FE21762|rigid:8HxL+I0HhpYmPFKhR7tkENKMuJs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZFX5	uniprotkb:P63261	intact:EBI-2851740|uniprotkb:Q0WGM4	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000458162.1|ensembl:ENSP00000458435.1|ensembl:ENSP00000459119.2|ensembl:ENSP00000459124.1|ensembl:ENSP00000460464.2|ensembl:ENSP00000460660.2|ensembl:ENSP00000461672.1|ensembl:ENSP00000466346.2|ensembl:ENSP00000477968.1|ensembl:ENSP00000505060.1|ensembl:ENSP00000505193.1|ensembl:ENSP00000505235.1|ensembl:ENSP00000506126.1|ensembl:ENSP00000506201.1|ensembl:ENSP00000506253.1|ensembl:ENSP00000516869.1|ensembl:ENSP00000516870.1|ensembl:ENSP00000516871.1|ensembl:ENSP00000516872.1|ensembl:ENSP00000516873.1|ensembl:ENSP00000516874.1|ensembl:ENSP00000516875.1|ensembl:ENSP00000516876.1|ensembl:ENSP00000516877.1|ensembl:ENSP00000516879.1|ensembl:ENSP00000516881.1|ensembl:ENSP00000516882.1|ensembl:ENSP00000516884.1|ensembl:ENSP00000516886.1|ensembl:ENSP00000516887.1	psi-mi:hisx_yerpe(display_long)|uniprotkb:hisD(gene name)|psi-mi:hisD(display_short)|uniprotkb:YPO1548(locus name)|uniprotkb:y2621(locus name)|uniprotkb:YP_1437(locus name)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876458|imex:IM-13779-8407	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR001692(Histidinol dehydrogenase)|interpro:IPR022695|interpro:IPR012131(Histidinol dehydrogenase, prokaryotic)|refseq:WP_002211895.1|go:""GO:0000105""(L-histidine biosynthetic process)|go:""GO:0004399""(histidinol dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0051287""(NAD binding)|refseq:YP_002346564.1|panther:PTHR21256(orthology-group)"	"efo:""Orphanet:2995""|efo:""Orphanet:90635""|efo:""Orphanet:98942""|efo:""Orphanet:98944""|ensembl:ENSG00000184009.13(gene)|ensembl:ENSG00000291420.1(gene)|ensembl:ENST00000570382.2(transcript)|ensembl:ENST00000571721.6(transcript)|ensembl:ENST00000573283.7(transcript)|ensembl:ENST00000575087.5(transcript)|ensembl:ENST00000575659.6(transcript)|ensembl:ENST00000575842.5(transcript)|ensembl:ENST00000575994.6(transcript)|ensembl:ENST00000576544.6(transcript)|ensembl:ENST00000615544.5(transcript)|ensembl:ENST00000679480.1(transcript)|ensembl:ENST00000679778.1(transcript)|ensembl:ENST00000680227.1(transcript)|ensembl:ENST00000680727.1(transcript)|ensembl:ENST00000681052.1(transcript)|ensembl:ENST00000681842.1(transcript)|ensembl:ENST00000707466.1(transcript)|ensembl:ENST00000707467.1(transcript)|ensembl:ENST00000707468.1(transcript)|ensembl:ENST00000707469.1(transcript)|ensembl:ENST00000707470.1(transcript)|ensembl:ENST00000707471.1(transcript)|ensembl:ENST00000707472.1(transcript)|ensembl:ENST00000707473.1(transcript)|ensembl:ENST00000707474.1(transcript)|ensembl:ENST00000707479.1(transcript)|ensembl:ENST00000707482.1(transcript)|ensembl:ENST00000707485.1(transcript)|ensembl:ENST00000707487.1(transcript)|ensembl:ENST00000707489.1(transcript)|ensembl:ENST00000707490.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005522""(profilin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007409""(axonogenesis)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030016""(myofibril)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031941""(filamentous actin)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048870""(cell motility)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0120192""(tight junction assembly)|go:""GO:0120220""(basal body patch)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902396""(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7NVM|rcsb pdb:8DNF|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|refseq:NP_001186883.1|refseq:NP_001605.1|panther:PTHR11937(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:aXT+/ioqFLvYG1ayljhfqLE1ikU632	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:05D923830E61D707|rigid:i8QEkac/HTl4zUAHug8NZac43rU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P60709	uniprotkb:A0A2S9PJH3	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|ensembl:ENSP00000494269.1|ensembl:ENSP00000494750.1|ensembl:ENSP00000495995.2|ensembl:ENSP00000501862.1|ensembl:ENSP00000502821.1|uniprotkb:Q96HG5	intact:EBI-2839884|uniprotkb:Q7CIZ2|uniprotkb:Q0WGC0	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:a0a2s9pjh3_yerpe(display_long)|uniprotkb:mgtC(gene name)|psi-mi:mgtC(display_short)|uniprotkb:YPO1660(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876477|imex:IM-13779-8406	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:673556""|efo:""Orphanet:674653""|ensembl:ENSG00000075624.17(gene)|ensembl:ENST00000493945.6(transcript)|ensembl:ENST00000642480.2(transcript)|ensembl:ENST00000646664.1(transcript)|ensembl:ENST00000674681.1(transcript)|ensembl:ENST00000675515.1(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0000786""(nucleosome)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007409""(axonogenesis)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019894""(kinesin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0022898""(regulation of transmembrane transporter activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030424""(axon)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0035060""(brahma complex)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045176""(apical protein localization)|go:""GO:0045202""(synapse)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048156""(tau protein binding)|go:""GO:0048870""(cell motility)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051621""(regulation of norepinephrine uptake)|go:""GO:0051623""(positive regulation of norepinephrine uptake)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070160""(tight junction)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071564""(npBAF complex)|go:""GO:0071565""(nBAF complex)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0072562""(blood microparticle)|go:""GO:0072749""(cellular response to cytochalasin B)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140092""(bBAF complex)|go:""GO:0140288""(GBAF complex)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000779""(regulation of double-strand break repair)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|rcsb pdb:7P1H|rcsb pdb:7QJ6|rcsb pdb:7QJ9|rcsb pdb:7VDV|rcsb pdb:7W28|rcsb pdb:7W29|rcsb pdb:7Y8R|rcsb pdb:7ZTC|rcsb pdb:7ZTD|rcsb pdb:8COG|rcsb pdb:8DNH|rcsb pdb:8IB8|rcsb pdb:8OI8|rcsb pdb:8OID|rcsb pdb:8QR1|rcsb pdb:8RTT|rcsb pdb:8RTY|rcsb pdb:8RU2|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|rcsb pdb:8XVT|rcsb pdb:9C57|rcsb pdb:9C62|rcsb pdb:9C6N|rcsb pdb:9FJM|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-9824585|reactome:R-HSA-983231|reactome:R-HSA-9845323|refseq:NP_001092.1|efo:""Orphanet:2995""|efo:""Orphanet:64755""|efo:""Orphanet:79107""|dip:DIP-29686N|panther:PTHR11937(orthology-group)"	"interpro:IPR003416(MgtC/SapB transporter)|interpro:IPR048640|interpro:IPR049177|go:""GO:0005886""(plasma membrane)|refseq:YP_002346668.1|panther:PTHR33778(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:uPB8dbfu1Sb5/L3fJ2zFWCc7gWs632	intact-crc:618ED64FA2587EF8|rigid:wUAwUZzYoxP+t6e1w4HNNA3P3qE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63261	uniprotkb:Q8CZW4	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000458162.1|ensembl:ENSP00000458435.1|ensembl:ENSP00000459119.2|ensembl:ENSP00000459124.1|ensembl:ENSP00000460464.2|ensembl:ENSP00000460660.2|ensembl:ENSP00000461672.1|ensembl:ENSP00000466346.2|ensembl:ENSP00000477968.1|ensembl:ENSP00000505060.1|ensembl:ENSP00000505193.1|ensembl:ENSP00000505235.1|ensembl:ENSP00000506126.1|ensembl:ENSP00000506201.1|ensembl:ENSP00000506253.1|ensembl:ENSP00000516869.1|ensembl:ENSP00000516870.1|ensembl:ENSP00000516871.1|ensembl:ENSP00000516872.1|ensembl:ENSP00000516873.1|ensembl:ENSP00000516874.1|ensembl:ENSP00000516875.1|ensembl:ENSP00000516876.1|ensembl:ENSP00000516877.1|ensembl:ENSP00000516879.1|ensembl:ENSP00000516881.1|ensembl:ENSP00000516882.1|ensembl:ENSP00000516884.1|ensembl:ENSP00000516886.1|ensembl:ENSP00000516887.1	intact:EBI-2851384|uniprotkb:Q74QA0	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:q8czw4_yerpe(display_long)|uniprotkb:y3277(locus name)|uniprotkb:fldB(gene name)|psi-mi:fldB(display_short)|uniprotkb:YP_3589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876451|imex:IM-13779-8405	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2995""|efo:""Orphanet:90635""|efo:""Orphanet:98942""|efo:""Orphanet:98944""|ensembl:ENSG00000184009.13(gene)|ensembl:ENSG00000291420.1(gene)|ensembl:ENST00000570382.2(transcript)|ensembl:ENST00000571721.6(transcript)|ensembl:ENST00000573283.7(transcript)|ensembl:ENST00000575087.5(transcript)|ensembl:ENST00000575659.6(transcript)|ensembl:ENST00000575842.5(transcript)|ensembl:ENST00000575994.6(transcript)|ensembl:ENST00000576544.6(transcript)|ensembl:ENST00000615544.5(transcript)|ensembl:ENST00000679480.1(transcript)|ensembl:ENST00000679778.1(transcript)|ensembl:ENST00000680227.1(transcript)|ensembl:ENST00000680727.1(transcript)|ensembl:ENST00000681052.1(transcript)|ensembl:ENST00000681842.1(transcript)|ensembl:ENST00000707466.1(transcript)|ensembl:ENST00000707467.1(transcript)|ensembl:ENST00000707468.1(transcript)|ensembl:ENST00000707469.1(transcript)|ensembl:ENST00000707470.1(transcript)|ensembl:ENST00000707471.1(transcript)|ensembl:ENST00000707472.1(transcript)|ensembl:ENST00000707473.1(transcript)|ensembl:ENST00000707474.1(transcript)|ensembl:ENST00000707479.1(transcript)|ensembl:ENST00000707482.1(transcript)|ensembl:ENST00000707485.1(transcript)|ensembl:ENST00000707487.1(transcript)|ensembl:ENST00000707489.1(transcript)|ensembl:ENST00000707490.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005522""(profilin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007409""(axonogenesis)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030016""(myofibril)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031941""(filamentous actin)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048870""(cell motility)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0120192""(tight junction assembly)|go:""GO:0120220""(basal body patch)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902396""(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7NVM|rcsb pdb:8DNF|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|refseq:NP_001186883.1|refseq:NP_001605.1|panther:PTHR11937(orthology-group)"	"interpro:IPR029039|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001226(Flavodoxin, conserved site)|interpro:IPR010086(Flavodoxin, long chain)|go:""GO:0009055""(electron transfer activity)|go:""GO:0010181""(FMN binding)|interpro:IPR050619"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:FZlCLDczSf2Gjm4UsIPSSoGJH6E632	intact-crc:72149E6A0E3E5F25|rigid:W3X7kCNuC/7mjAuqkfSwnO/pnD4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63261	uniprotkb:P46357	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000458162.1|ensembl:ENSP00000458435.1|ensembl:ENSP00000459119.2|ensembl:ENSP00000459124.1|ensembl:ENSP00000460464.2|ensembl:ENSP00000460660.2|ensembl:ENSP00000461672.1|ensembl:ENSP00000466346.2|ensembl:ENSP00000477968.1|ensembl:ENSP00000505060.1|ensembl:ENSP00000505193.1|ensembl:ENSP00000505235.1|ensembl:ENSP00000506126.1|ensembl:ENSP00000506201.1|ensembl:ENSP00000506253.1|ensembl:ENSP00000516869.1|ensembl:ENSP00000516870.1|ensembl:ENSP00000516871.1|ensembl:ENSP00000516872.1|ensembl:ENSP00000516873.1|ensembl:ENSP00000516874.1|ensembl:ENSP00000516875.1|ensembl:ENSP00000516876.1|ensembl:ENSP00000516877.1|ensembl:ENSP00000516879.1|ensembl:ENSP00000516881.1|ensembl:ENSP00000516882.1|ensembl:ENSP00000516884.1|ensembl:ENSP00000516886.1|ensembl:ENSP00000516887.1	intact:EBI-2876465|uniprotkb:Q0WAG5	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:dapf_yerpe(display_long)|uniprotkb:dapF(gene name)|psi-mi:dapF(display_short)|uniprotkb:PLP-independent amino acid racemase(gene name synonym)|uniprotkb:YPO3845(locus name)|uniprotkb:YP_3202(locus name)|uniprotkb:y0385(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876470|imex:IM-13779-8408	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2995""|efo:""Orphanet:90635""|efo:""Orphanet:98942""|efo:""Orphanet:98944""|ensembl:ENSG00000184009.13(gene)|ensembl:ENSG00000291420.1(gene)|ensembl:ENST00000570382.2(transcript)|ensembl:ENST00000571721.6(transcript)|ensembl:ENST00000573283.7(transcript)|ensembl:ENST00000575087.5(transcript)|ensembl:ENST00000575659.6(transcript)|ensembl:ENST00000575842.5(transcript)|ensembl:ENST00000575994.6(transcript)|ensembl:ENST00000576544.6(transcript)|ensembl:ENST00000615544.5(transcript)|ensembl:ENST00000679480.1(transcript)|ensembl:ENST00000679778.1(transcript)|ensembl:ENST00000680227.1(transcript)|ensembl:ENST00000680727.1(transcript)|ensembl:ENST00000681052.1(transcript)|ensembl:ENST00000681842.1(transcript)|ensembl:ENST00000707466.1(transcript)|ensembl:ENST00000707467.1(transcript)|ensembl:ENST00000707468.1(transcript)|ensembl:ENST00000707469.1(transcript)|ensembl:ENST00000707470.1(transcript)|ensembl:ENST00000707471.1(transcript)|ensembl:ENST00000707472.1(transcript)|ensembl:ENST00000707473.1(transcript)|ensembl:ENST00000707474.1(transcript)|ensembl:ENST00000707479.1(transcript)|ensembl:ENST00000707482.1(transcript)|ensembl:ENST00000707485.1(transcript)|ensembl:ENST00000707487.1(transcript)|ensembl:ENST00000707489.1(transcript)|ensembl:ENST00000707490.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005522""(profilin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007409""(axonogenesis)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030016""(myofibril)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031941""(filamentous actin)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048870""(cell motility)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0120192""(tight junction assembly)|go:""GO:0120220""(basal body patch)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902396""(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7NVM|rcsb pdb:8DNF|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|refseq:NP_001186883.1|refseq:NP_001605.1|panther:PTHR11937(orthology-group)"	"go:""GO:0005829""(cytosol)|go:""GO:0008837""(diaminopimelate epimerase activity)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|interpro:IPR018510|interpro:IPR001653(Diaminopimelate epimerase)|refseq:WP_002211471.1|refseq:YP_002348723.1|panther:PTHR31689(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:xuaZCbeXzx9X+tf9OGYiOUiKqxE632	intact-crc:5260BDC19FBDCD19|rigid:SMr+2X/nqTZKdJHUop9bDgw7N04	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96CM8	uniprotkb:Q74YC7	intact:EBI-2876502|ensembl:ENSP00000300441.4|uniprotkb:Q9H7G2|uniprotkb:B4DFQ6|uniprotkb:B4DHT5|uniprotkb:B4DUF5	intact:EBI-2846807|uniprotkb:Q7CL56|uniprotkb:Q74WT4|uniprotkb:Q9R8C8	psi-mi:acsf2_human(display_long)|uniprotkb:ACSF2(gene name)|psi-mi:ACSF2(display_short)|uniprotkb:UNQ493/PRO1009(orf name)	psi-mi:q74yc7_yerpe(display_long)|uniprotkb:Y1011(locus name)|uniprotkb:YP_0019(locus name)|uniprotkb:YP_0098(locus name)|uniprotkb:YP_0753(locus name)|uniprotkb:YP_0965(locus name)|uniprotkb:YP_1056(locus name)|uniprotkb:YP_1168(locus name)|uniprotkb:YP_1187(locus name)|uniprotkb:YP_1224(locus name)|uniprotkb:YP_2098(locus name)|uniprotkb:YP_2182(locus name)|uniprotkb:YP_2252(locus name)|uniprotkb:YP_2621(locus name)|uniprotkb:YP_3010(locus name)|uniprotkb:YP_3331(locus name)|uniprotkb:YP_3517(locus name)|uniprotkb:YP_3905(locus name)|uniprotkb:y0225(locus name)|uniprotkb:y0377(locus name)|uniprotkb:y0466(locus name)|uniprotkb:y0486(locus name)|uniprotkb:y0889(locus name)|uniprotkb:y0898(locus name)|uniprotkb:y1007(locus name)|uniprotkb:y1312(locus name)|uniprotkb:y1420(locus name)|uniprotkb:y1484(locus name)|uniprotkb:y1768(locus name)|uniprotkb:y1978(locus name)|uniprotkb:y2764(locus name)|uniprotkb:y2808(locus name)|uniprotkb:y2965(locus name)|uniprotkb:y3080(locus name)|uniprotkb:y3481(locus name)|uniprotkb:y3644(locus name)|uniprotkb:y3810(locus name)|uniprotkb:y3861(locus name)|uniprotkb:ORF46(gene name)|psi-mi:ORF46(display_short)|uniprotkb:tnp(gene name synonym)|uniprotkb:tnpA(gene name synonym)|uniprotkb:tnp_1(gene name synonym)|uniprotkb:tnp_10(gene name synonym)|uniprotkb:tnp_13(gene name synonym)|uniprotkb:tnp_14(gene name synonym)|uniprotkb:tnp_15(gene name synonym)|uniprotkb:tnp_16(gene name synonym)|uniprotkb:tnp_2(gene name synonym)|uniprotkb:tnp_20(gene name synonym)|uniprotkb:tnp_23(gene name synonym)|uniprotkb:tnp_25(gene name synonym)|uniprotkb:tnp_28(gene name synonym)|uniprotkb:tnp_34(gene name synonym)|uniprotkb:tnp_37(gene name synonym)|uniprotkb:tnp_38(gene name synonym)|uniprotkb:tnp_44(gene name synonym)|uniprotkb:tnp_7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876507|imex:IM-13779-8410	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000167107.13(gene)|ensembl:ENST00000300441.9(transcript)|go:""GO:0004467""(long-chain fatty acid-CoA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0006637""(acyl-CoA metabolic process)|go:""GO:0031956""(medium-chain fatty acid-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR045851|mint:Q96CM8|reactome:R-HSA-77289|refseq:NP_079425.3|refseq:NP_001275901.1|refseq:NP_001275897.1|refseq:NP_001275898.1|refseq:NP_001275899.1|refseq:NP_001275900.1|panther:PTHR43201(orthology-group)"	"interpro:IPR002686(Transposase IS200-like)|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|interpro:IPR036515"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yn41ilnswMEfm0Y8mmbhKneGJdU9606	rogid:jQUYsyhxUhxhbwocUkkJmUXu2pE632	intact-crc:A4DD95D97871DD77|rigid:JtCGm6C42BBbU8L9ISmqauVbtRE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P53396	uniprotkb:A0A5P8YB02	intact:EBI-1042794|uniprotkb:Q13037|uniprotkb:Q9BRL0|uniprotkb:B4DIM0|uniprotkb:B4E3P0|ensembl:ENSP00000253792.2|ensembl:ENSP00000466259.1	intact:EBI-2852267|uniprotkb:Q74QW9|uniprotkb:A0A0H2W7I3|uniprotkb:Q7CG03|uniprotkb:A0A384L523	"psi-mi:acly_human(display_long)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short)|uniprotkb:""ATP-citrate (pro-S-)-lyase""(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym)"	psi-mi:a0a5p8yb02_yerpe(display_long)|uniprotkb:YPO3973(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876521|imex:IM-13779-8413	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001087.2|refseq:NP_942127.1|refseq:XP_005257452.1|refseq:NP_001290203.1|refseq:NP_001290204.1|refseq:XP_016880177.1|ensembl:ENSG00000131473.17(gene)|ensembl:ENST00000352035.7(transcript)|ensembl:ENST00000590151.5(transcript)|go:""GO:0003878""(ATP citrate synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006085""(acetyl-CoA biosynthetic process)|go:""GO:0006101""(citrate metabolic process)|go:""GO:0006107""(oxaloacetate metabolic process)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0008610""(lipid biosynthetic process)|go:""GO:0015936""(coenzyme A metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR014608(ATP-citrate synthase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR017866|interpro:IPR032263|interpro:IPR033847|interpro:IPR036291|interpro:IPR036969|mint:P53396|rcsb pdb:3MWD|rcsb pdb:3MWE|rcsb pdb:3PFF|rcsb pdb:5TDE|rcsb pdb:5TDF|rcsb pdb:5TDM|rcsb pdb:5TDZ|rcsb pdb:5TE1|rcsb pdb:5TEQ|rcsb pdb:5TES|rcsb pdb:5TET|rcsb pdb:6HXH|rcsb pdb:6HXK|rcsb pdb:6HXL|rcsb pdb:6HXM|rcsb pdb:6O0H|rcsb pdb:6POE|rcsb pdb:6POF|rcsb pdb:6QFB|rcsb pdb:6UI9|rcsb pdb:6UIA|rcsb pdb:6UUW|rcsb pdb:6UUZ|rcsb pdb:6UV5|rcsb pdb:6Z2H|rcsb pdb:7LIW|rcsb pdb:7LJ9|rcsb pdb:7LLA|rcsb pdb:7RIG|rcsb pdb:7RKZ|rcsb pdb:7RMP|rcsb pdb:8G1E|rcsb pdb:8G1F|rcsb pdb:8G5C|rcsb pdb:8G5D|reactome:R-HSA-163765|reactome:R-HSA-6798695|reactome:R-HSA-75105|panther:PTHR23118(orthology-group)"	"interpro:IPR024079|interpro:IPR016294(Peptidase M10B)|interpro:IPR013858(Peptidase M10,  serralysin, C-terminal)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|interpro:IPR019960|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0031012""(extracellular matrix)|interpro:IPR034033|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|refseq:YP_002348843.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NaxO5aRi08GTrEV9aIboUdTlpAs9606	rogid:flDgYZ62TnAy5NPdVdn4WU9GM3Q632	intact-crc:0D26B04584E13D7F|rigid:Yk50+K5wQD/bJec4ZFIa4NzgJiI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y305	uniprotkb:Q8CZX8	intact:EBI-2548214|uniprotkb:B3KNC9|uniprotkb:B7ZM94|ensembl:ENSP00000336580.7	intact:EBI-2842787|uniprotkb:Q74S00	psi-mi:acot9_human(display_long)|uniprotkb:ACOT9(gene name)|psi-mi:ACOT9(display_short)|uniprotkb:Acyl-CoA thioester hydrolase 9(gene name synonym)|uniprotkb:CGI-16(orf name)	psi-mi:q8czx8_yerpe(display_long)|uniprotkb:lysR(gene name)|psi-mi:lysR(display_short)|uniprotkb:lysR17(gene name synonym)|uniprotkb:YP_2860(locus name)|uniprotkb:y3185(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876514|imex:IM-13779-8411	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001028755.2|refseq:NP_001032248.1|ensembl:ENSG00000123130.17(gene)|ensembl:ENST00000336430.11(transcript)|go:""GO:0003986""(acetyl-CoA hydrolase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006637""(acyl-CoA metabolic process)|go:""GO:0047617""(fatty acyl-CoA hydrolase activity)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0052816""(long-chain fatty acyl-CoA hydrolase activity)|interpro:IPR006683(Thioesterase superfamily)|interpro:IPR029069|interpro:IPR033120|mint:Q9Y305|reactome:R-HSA-77289|refseq:NP_001317188.1|panther:PTHR12655(orthology-group)"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WbPOPMGV/9XQRxLufTKCXvYQH/Y9606	rogid:EsQj+JSnKznEgjvjnq0+lLlaUlg632	intact-crc:51F766BE948EB5F3|rigid:TtzhQFx4pithftqPewKDs0Ni+sk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62736	uniprotkb:A0A3G5LAD2	intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784.6|ensembl:ENSP00000396730.2|ensembl:ENSP00000398239.2|ensembl:ENSP00000518893.1|ensembl:ENSP00000518895.1|ensembl:ENSP00000518898.1	intact:EBI-2876484	psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name)	psi-mi:a0a3g5lad2_yerpe(display_long)|uniprotkb:y2387(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876488|imex:IM-13779-8409	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000107796.14(gene)|ensembl:ENST00000224784.10(transcript)|ensembl:ENST00000415557.2(transcript)|ensembl:ENST00000458159.6(transcript)|ensembl:ENST00000713597.1(transcript)|ensembl:ENST00000713599.1(transcript)|ensembl:ENST00000713602.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005524""(ATP binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009615""(response to virus)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014829""(vascular associated smooth muscle contraction)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030175""(filopodium)|go:""GO:0030485""(smooth muscle contractile fiber)|go:""GO:0031514""(motile cilium)|go:""GO:0032991""(protein-containing complex)|go:""GO:0044297""(cell body)|go:""GO:0061870""(positive regulation of hepatic stellate cell migration)|go:""GO:0061874""(positive regulation of hepatic stellate cell contraction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0072051""(juxtaglomerular apparatus development)|go:""GO:0072144""(glomerular mesangial cell development)|go:""GO:0090131""(mesenchyme migration)|go:""GO:2000491""(positive regulation of hepatic stellate cell activation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695|refseq:NP_001135417.1|refseq:NP_001307784.1|refseq:NP_001604.1|efo:""Orphanet:2573""|efo:""Orphanet:404463""|efo:""Orphanet:91387""|panther:PTHR11937(orthology-group)"	"go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005886""(plasma membrane)|uniprotkb:A0A5P8YEJ8(uniprot-removed-ac)|interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR011006(CheY-like)|interpro:IPR036097|interpro:IPR036890|interpro:IPR049870|interpro:IPR049871"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606	rogid:CbxF55tk5pzTv/3jGEf3Z4bz2Bw632	intact-crc:5AE6BE060C8E9C00|rigid:eC55gNFpsElWI1NwuA+jAOsJYfU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHF1	uniprotkb:P62736	intact:EBI-2849437|uniprotkb:Q0WI93	intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784.6|ensembl:ENSP00000396730.2|ensembl:ENSP00000398239.2|ensembl:ENSP00000518893.1|ensembl:ENSP00000518895.1|ensembl:ENSP00000518898.1	psi-mi:glsa1_yerpe(display_long)|uniprotkb:glsA1(gene name)|psi-mi:glsA1(display_short)|uniprotkb:YPO0949(locus name)|uniprotkb:y3336(locus name)|uniprotkb:YP_3492(locus name)	psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876495|imex:IM-13779-8412	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|refseq:WP_002209989.1|go:""GO:0004359""(glutaminase activity)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006543""(glutamine catabolic process)|refseq:YP_002345995.1|panther:PTHR12544(orthology-group)"	"ensembl:ENSG00000107796.14(gene)|ensembl:ENST00000224784.10(transcript)|ensembl:ENST00000415557.2(transcript)|ensembl:ENST00000458159.6(transcript)|ensembl:ENST00000713597.1(transcript)|ensembl:ENST00000713599.1(transcript)|ensembl:ENST00000713602.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005524""(ATP binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0009615""(response to virus)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014829""(vascular associated smooth muscle contraction)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030175""(filopodium)|go:""GO:0030485""(smooth muscle contractile fiber)|go:""GO:0031514""(motile cilium)|go:""GO:0032991""(protein-containing complex)|go:""GO:0044297""(cell body)|go:""GO:0061870""(positive regulation of hepatic stellate cell migration)|go:""GO:0061874""(positive regulation of hepatic stellate cell contraction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0072051""(juxtaglomerular apparatus development)|go:""GO:0072144""(glomerular mesangial cell development)|go:""GO:0090131""(mesenchyme migration)|go:""GO:2000491""(positive regulation of hepatic stellate cell activation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695|refseq:NP_001135417.1|refseq:NP_001307784.1|refseq:NP_001604.1|efo:""Orphanet:2573""|efo:""Orphanet:404463""|efo:""Orphanet:91387""|panther:PTHR11937(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RXiLjz5WJJYlM97YSg1neu4h+FA632	rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606	intact-crc:D6AB3832157027C1|rigid:Qt3zP574UfHqkty5Tq1oPM3NzrY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94929	uniprotkb:A0A1U8QSD0	intact:EBI-351267|uniprotkb:A8K121|uniprotkb:Q19VH3|uniprotkb:Q658S1|uniprotkb:Q68CI5|uniprotkb:Q9BV32|ensembl:ENSP00000310309.7|ensembl:ENSP00000425394.1	intact:EBI-2851086|uniprotkb:Q74YG8|uniprotkb:Q65AD8|uniprotkb:Q9ZGZ0	psi-mi:ablm3_human(display_long)|uniprotkb:ABLIM3(gene name)|psi-mi:ABLIM3(display_short)|uniprotkb:HMFN1661(orf name)|uniprotkb:KIAA0843(gene name synonym)|uniprotkb:Actin-binding LIM protein family member 3(gene name synonym)	psi-mi:a0a1u8qsd0_yerpe(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876546|imex:IM-13779-8415	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055760.1|ensembl:ENSG00000173210.21(gene)|ensembl:ENST00000309868.12(transcript)|ensembl:ENST00000506113.5(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005737""(cytoplasm)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0060271""(cilium assembly)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003128(Villin headpiece)|interpro:IPR032402|interpro:IPR036886|interpro:IPR051618|mint:O94929|rcsb pdb:1UJS|rcsb pdb:2DJ7|reactome:R-HSA-418885|refseq:NP_001287944.1|refseq:NP_001287947.1|refseq:NP_001287957.1|refseq:NP_001287956.1|refseq:NP_001332787.1|refseq:NP_001332788.1|refseq:NP_001332789.1|refseq:NP_001332790.1|panther:PTHR24213(orthology-group)"	"refseq:YP_094011.1|interpro:IPR025188|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hkH6gCL3p11Wrl6ixVvtl/MGhsI9606	rogid:7V6Si5eR8IhffjxNCN0T7bRZj70632	intact-crc:73E1623AB5DD56C9|rigid:x5GVQ8dkHv6eS7TJsBYnwbYZUHM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIF7	uniprotkb:Q8WU67	intact:EBI-2876354|uniprotkb:Q0WJC0	intact:EBI-2876553|ensembl:ENSP00000289119.2|uniprotkb:O43411|uniprotkb:B0YIV0|uniprotkb:B7Z5C2	"psi-mi:rsmh_yerpe(display_long)|uniprotkb:rsmH(gene name)|psi-mi:rsmH(display_short)|uniprotkb:mraW(gene name synonym)|uniprotkb:""16S rRNA m(4)C1402 methyltransferase""(gene name synonym)|uniprotkb:""rRNA (cytosine-N(4)-)-methyltransferase RsmH""(gene name synonym)|uniprotkb:YPO0547(locus name)|uniprotkb:y3634(locus name)|uniprotkb:YP_3637(locus name)"	psi-mi:abhd3_human(display_long)|uniprotkb:ABHD3(gene name)|psi-mi:ABHD3(display_short)|uniprotkb:Abhydrolase domain-containing protein 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876559|imex:IM-13779-8417	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0070475""(rRNA base methylation)|go:""GO:0071424""(""rRNA (cytosine-N4-)-methyltransferase activity"")|interpro:IPR002903(Bacterial methyltransferase)|interpro:IPR023397|interpro:IPR029063|refseq:WP_002210442.1|refseq:YP_002345618.1|panther:PTHR11265(orthology-group)"	"ensembl:ENSG00000158201.10(gene)|ensembl:ENST00000289119.7(transcript)|go:""GO:0004623""(phospholipase A2 activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006656""(phosphatidylcholine biosynthetic process)|go:""GO:0008126""(acetylesterase activity)|go:""GO:0008970""(phospholipase A1 activity)|go:""GO:0046470""(phosphatidylcholine metabolic process)|go:""GO:0047372""(monoacylglycerol lipase activity)|go:""GO:0047498""(calcium-dependent phospholipase A2 activity)|go:""GO:0047499""(calcium-independent phospholipase A2 activity)|go:""GO:0051792""(medium-chain fatty acid biosynthetic process)|go:""GO:0051793""(medium-chain fatty acid catabolic process)|go:""GO:0052739""(obsolete phosphatidylserine 1-acylhydrolase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR029058|interpro:IPR050960|mint:Q8WU67|reactome:R-HSA-1483191|refseq:NP_001295185.1|refseq:NP_001295186.1|refseq:NP_612213.2|panther:PTHR10794(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OGgbezdpTIhwZTTf5sTpYdun8CY632	rogid:QGMm0R1GsOz+kODPipFvZi1/tqg9606	intact-crc:AA87A4DC31C4BA38|rigid:UvS8VVDH4/E/rK+BmtKP4QrIHWE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YHG9	uniprotkb:O96019	intact:EBI-2876531|uniprotkb:Q0WCP8|uniprotkb:Q74SG5|uniprotkb:A0A384KAE1|uniprotkb:Q7CJH4	intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552.2	psi-mi:a0a5p8yhg9_yerpe(display_long)|uniprotkb:YPO3018(locus name)	psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876528|imex:IM-13779-8416	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_002347940.1	"ensembl:ENSG00000136518.17(gene)|ensembl:ENST00000429709.7(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0000786""(nucleosome)|go:""GO:0001825""(blastocyst formation)|go:""GO:0003407""(neural retina development)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006282""(regulation of DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007165""(signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0021510""(spinal cord development)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0031011""(Ino80 complex)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033044""(regulation of chromosome organization)|go:""GO:0035060""(brahma complex)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060382""(regulation of DNA strand elongation)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0071564""(npBAF complex)|go:""GO:0140288""(GBAF complex)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:1904507""(positive regulation of telomere maintenance in response to DNA damage)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000779""(regulation of double-strand break repair)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|rcsb pdb:7VDV|rcsb pdb:7Y8R|rcsb pdb:8QR1|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|rcsb pdb:8XVG|rcsb pdb:8XVT|rcsb pdb:9C4B|rcsb pdb:9C57|rcsb pdb:9C62|rcsb pdb:9C6N|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|reactome:R-HSA-9824585|reactome:R-HSA-9845323|refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|efo:""Orphanet:528084""|dip:DIP-27565N|panther:PTHR11937(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cOpzU61YGvr7AXEorVfvZhIjSUI632	rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606	intact-crc:ACE377D5B41B2FF8|rigid:KWZ4iQqOvQDSDOPFmbHyGYSIUcI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11310	uniprotkb:Q74SR9	intact:EBI-514381|uniprotkb:Q9NYF1|uniprotkb:Q5T4U4|ensembl:ENSP00000359878.5	intact:EBI-2870466|uniprotkb:Q8D102	psi-mi:acadm_human(display_long)|uniprotkb:Medium chain acyl-CoA dehydrogenase(gene name synonym)|uniprotkb:ACADM(gene name)|psi-mi:ACADM(display_short)	psi-mi:trmn6_yerpe(display_long)|uniprotkb:tRNA m6A37 methyltransferase(gene name synonym)|uniprotkb:YPO2709(locus name)|uniprotkb:y1288(locus name)|uniprotkb:YP_2513(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876539|imex:IM-13779-8414	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:42""|ensembl:ENSG00000117054.15(gene)|ensembl:ENST00000370841.9(transcript)|go:""GO:0001889""(liver development)|go:""GO:0003995""(acyl-CoA dehydrogenase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005978""(glycogen biosynthetic process)|go:""GO:0006111""(regulation of gluconeogenesis)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0009409""(response to cold)|go:""GO:0009791""(post-embryonic development)|go:""GO:0019254""(carnitine metabolic process, CoA-linked)|go:""GO:0030424""(axon)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0033539""(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:""GO:0042594""(response to starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045329""(carnitine biosynthetic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0051791""(medium-chain fatty acid metabolic process)|go:""GO:0051793""(medium-chain fatty acid catabolic process)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0070991""(medium-chain fatty acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|interpro:IPR046373|interpro:IPR050741|mint:P11310|rcsb pdb:1EGC|rcsb pdb:1EGD|rcsb pdb:1EGE|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:4P13|rcsb pdb:8SGP|reactome:R-HSA-1989781|reactome:R-HSA-77288|reactome:R-HSA-77346|reactome:R-HSA-77348|refseq:NP_000007.1|refseq:NP_001120800.1|panther:PTHR48083(orthology-group)|dip:DIP-34281N"	"interpro:IPR007848(Methyltransferase small)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR022882|interpro:IPR029063|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008033""(tRNA processing)|go:""GO:0016430""(""tRNA (adenine-N6)-methyltransferase activity"")|go:""GO:0032259""(methylation)|interpro:IPR050210|refseq:YP_002347656.1|panther:PTHR47739(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rfmTmYKNQr6R6ikvfYovZIctoz49606	rogid:kJv76ElYOsTNIT1vfGsoqJO/4sY632	intact-crc:0A8E3FF17B5D59DB|rigid:2WYpRg6ZJdIcJdu7kX8+D+up47U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D016	uniprotkb:Q13685	intact:EBI-2845497|uniprotkb:Q74WF8	intact:EBI-727274|uniprotkb:Q8WUJ9|uniprotkb:Q96H92|ensembl:ENSP00000248450.4	psi-mi:q8d016_yerpe(display_long)|uniprotkb:melB1(gene name)|psi-mi:melB1(display_short)|uniprotkb:YP_0913(locus name)|uniprotkb:y2961(locus name)	psi-mi:aamp_human(display_long)|uniprotkb:AAMP(gene name)|psi-mi:AAMP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876594|imex:IM-13779-8422	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039672|go:""GO:0008643""(carbohydrate transport)|go:""GO:0015293""(symporter activity)|go:""GO:0016020""(membrane)|interpro:IPR036259"	"refseq:NP_001078.2|ensembl:ENSG00000127837.10(gene)|ensembl:ENST00000248450.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0014909""(smooth muscle cell migration)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030154""(cell differentiation)|go:""GO:0045171""(intercellular bridge)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR051179|mint:Q13685|reactome:R-HSA-168638|reactome:R-HSA-177929|reactome:R-HSA-194138|reactome:R-HSA-428930|panther:PTHR19857(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4DMhRYiG74JOcoym6GZ7F4fsxLM632	rogid:H0UzaZMC4fjo4QAXNdfy0BIWmw09606	intact-crc:E0753895727EC235|rigid:0VKB4zV0OjaZtaovWmdi3VpOJGg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YEP4	uniprotkb:Q9BZC7	intact:EBI-2842292|uniprotkb:Q74UV4|uniprotkb:Q7CHX9|uniprotkb:A0A2S9PKJ9|uniprotkb:Q0WFZ1	intact:EBI-311024|uniprotkb:A6NED5|uniprotkb:Q5W9G5|uniprotkb:Q76MW7|uniprotkb:Q5SPY5|intact:EBI-3866765|uniprotkb:Q9HC28|ensembl:ENSP00000360666.3	psi-mi:a0a5p8yep4_yerpe(display_long)|uniprotkb:Fla FV(gene name)|psi-mi:Fla FV(display_short)|uniprotkb:flaK(gene name synonym)|uniprotkb:flgE(gene name synonym)|uniprotkb:YPO1802(locus name)	psi-mi:abca2_human(display_long)|uniprotkb:ABCA2(gene name)|psi-mi:ABCA2(display_short)|uniprotkb:ABC2(gene name synonym)|uniprotkb:KIAA1062(gene name synonym)|uniprotkb:ATP-binding cassette transporter 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876566|imex:IM-13779-8421	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR019776|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:WP_002211113.1|interpro:IPR037058|interpro:IPR037925|interpro:IPR053967|refseq:YP_002346797.1"	"efo:""Orphanet:88616""|ensembl:ENSG00000107331.18(gene)|ensembl:ENST00000371605.7(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0001573""(ganglioside metabolic process)|go:""GO:0005319""(lipid transporter activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006684""(sphingomyelin metabolic process)|go:""GO:0006687""(glycosphingolipid metabolic process)|go:""GO:0006869""(lipid transport)|go:""GO:0007626""(locomotory behavior)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019218""(regulation of steroid metabolic process)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032289""(central nervous system myelin formation)|go:""GO:0032383""(regulation of intracellular cholesterol transport)|go:""GO:0032384""(negative regulation of intracellular cholesterol transport)|go:""GO:0032805""(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042986""(positive regulation of amyloid precursor protein biosynthetic process)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045939""(negative regulation of steroid metabolic process)|go:""GO:0046512""(sphingosine biosynthetic process)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0055085""(transmembrane transport)|go:""GO:0060049""(regulation of protein glycosylation)|go:""GO:0061135""(endopeptidase regulator activity)|go:""GO:0070723""(response to cholesterol)|go:""GO:0071072""(negative regulation of phospholipid biosynthetic process)|go:""GO:0090155""(negative regulation of sphingolipid biosynthetic process)|go:""GO:0090156""(intracellular sphingolipid homeostasis)|go:""GO:0090370""(negative regulation of cholesterol efflux)|go:""GO:0099038""(ceramide floppase activity)|go:""GO:0099040""(ceramide translocation)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901873""(regulation of post-translational protein modification)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902993""(positive regulation of amyloid precursor protein catabolic process)|go:""GO:1904375""(regulation of protein localization to cell periphery)|go:""GO:1905601""(negative regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:""GO:2000008""(regulation of protein localization to cell surface)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR026082|interpro:IPR027417|mint:Q9BZC7|reactome:R-HSA-1369062|refseq:NP_001597.2|refseq:NP_997698.1|refseq:XP_006717059.1|panther:PTHR19229(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BoYVEh/qtD+LMyJcZpSfUZt9yTk632	rogid:0R9SMBvlpKcrbgL2J8Q5kaxy/O89606	intact-crc:0CD222AFB927CB21|rigid:tZ/BUXw/pqUhOCamZtyFdVFLsec	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NRW3	uniprotkb:Q8ZCS5	intact:EBI-1044593|uniprotkb:Q5JZ92|uniprotkb:Q7Z2N7|uniprotkb:Q96F12|uniprotkb:B2R884|ensembl:ENSP00000355340.3	intact:EBI-2870801|uniprotkb:Q0WD12|uniprotkb:Q8D0Z5	psi-mi:abc3c_human(display_long)|uniprotkb:APOBEC1-like(gene name synonym)|uniprotkb:Phorbolin I(gene name synonym)|uniprotkb:APOBEC3C(gene name)|psi-mi:APOBEC3C(display_short)|uniprotkb:APOBEC1L(gene name synonym)|uniprotkb:PBI(gene name synonym)	psi-mi:hsca_yerpe(display_long)|uniprotkb:hscA(gene name)|psi-mi:hscA(display_short)|uniprotkb:Hsc66(gene name synonym)|uniprotkb:YPO2892(locus name)|uniprotkb:y1339(locus name)|uniprotkb:YP_2563(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876573|imex:IM-13779-8418	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055323.2|dip:DIP-48919N|ensembl:ENSG00000244509.4(gene)|ensembl:ENST00000361441.5(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0004126""(cytidine deaminase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009972""(cytidine deamination)|go:""GO:0010526""(transposable element silencing)|go:""GO:0016554""(cytidine to uridine editing)|go:""GO:0044029""(positive regulation of gene expression via chromosomal CpG island demethylation)|go:""GO:0044355""(clearance of foreign intracellular DNA)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045869""(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:""GO:0051607""(defense response to virus)|go:""GO:0070383""(DNA cytosine deamination)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR050610|mint:Q9NRW3|rcsb pdb:3VM8|rcsb pdb:3VOW|reactome:R-HSA-72200|reactome:R-HSA-75094|panther:PTHR13857(orthology-group)"	"interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR010236(ISC system FeS cluster assembly, HscA chaperone)|interpro:IPR029047|interpro:IPR029048|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR042039|interpro:IPR043129|refseq:YP_002347826.1|refseq:WP_002209832.1|panther:PTHR19375(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:ux+DxCCQm60aF6LNr1Q4atd5ZFU9606	rogid:9VlLUc2foa/q8oeKFZrKcUalLq4632	intact-crc:B05623217C482B8F|rigid:QcFAdUNXTxRL3XPhpULWjeE47tw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D192	uniprotkb:Q7Z5R6	intact:EBI-2842738|uniprotkb:Q74XQ4	intact:EBI-2818084|uniprotkb:Q8IWS8|uniprotkb:Q8IZZ7|ensembl:ENSP00000365411.4|intact:EBI-9091217|uniprotkb:Q8IYL7	psi-mi:q8d192_yerpe(display_long)|uniprotkb:cirA2(gene name)|psi-mi:cirA2(display_short)|uniprotkb:YP_0347(locus name)|uniprotkb:y0850(locus name)	psi-mi:ab1ip_human(display_long)|uniprotkb:APBB1IP(gene name)|psi-mi:APBB1IP(display_short)|uniprotkb:PREL1(gene name synonym)|uniprotkb:RARP1(gene name synonym)|uniprotkb:RIAM(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 73(gene name synonym)|uniprotkb:Rap1-GTP-interacting adapter molecule(gene name synonym)|uniprotkb:Retinoic acid-responsive proline-rich protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876580|imex:IM-13779-8420	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|go:""GO:0009279""(cell outer membrane)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426"	"refseq:NP_061916.3|refseq:XP_006717514.1|ensembl:ENSG00000077420.17(gene)|ensembl:ENST00000376236.9(transcript)|go:""GO:0002291""(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0030027""(lamellipodium)|go:""GO:0042101""(T cell receptor complex)|go:""GO:0045785""(positive regulation of cell adhesion)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|mint:Q7Z5R6|rcsb pdb:2MWN|rcsb pdb:3ZDL|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR11243(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RzjHHCxJ6rMwWCbWf+N47U3e7QQ632	rogid:PLBPCQJk3g1jocBsOm6vYnsTRpU9606	intact-crc:474884D777D23A68|rigid:kEQOlXrIeLL8USmYBCqdsRDmsSY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BTE6	uniprotkb:Q8D166	intact:EBI-2796199|uniprotkb:B4DI73|ensembl:ENSP00000400870.1	intact:EBI-2840565	psi-mi:aasd1_human(display_long)|uniprotkb:Alanyl-tRNA synthetase domain-containing protein 1(gene name synonym)|uniprotkb:AARSD1(gene name)|psi-mi:AARSD1(display_short)	psi-mi:q8d166_yerpe(display_long)|uniprotkb:ggt(gene name)|psi-mi:ggt(display_short)|uniprotkb:ggt_1(gene name synonym)|uniprotkb:NCTC5923_01128(orf name)|uniprotkb:y0985(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876587|imex:IM-13779-8419	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079543.1|refseq:NP_001129514.2|refseq:NP_001248363.1|ensembl:ENSG00000266967.7(gene)|ensembl:ENST00000427569.7(transcript)|go:""GO:0002196""(""Ser-tRNA(Ala) deacylase activity"")|go:""GO:0003676""(nucleic acid binding)|go:""GO:0004813""(alanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006419""(alanyl-tRNA aminoacylation)|go:""GO:0006450""(regulation of translational fidelity)|go:""GO:0046872""(metal ion binding)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018163|interpro:IPR018165|interpro:IPR051335|mint:Q9BTE6|panther:PTHR43462(orthology-group)"	"interpro:IPR000101(Gamma-glutamyltranspeptidase)|go:""GO:0006750""(glutathione biosynthetic process)|go:""GO:0006751""(glutathione catabolic process)|go:""GO:0036374""(glutathione hydrolase activity)|go:""GO:0103068""(leukotriene C4 gamma-glutamyl transferase activity)|interpro:IPR055262|interpro:IPR029055|interpro:IPR043137|interpro:IPR043138|refseq:WP_002216937.1|interpro:IPR051792"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lTVaIdskWMt9ad808OfOSBPN9jg9606	rogid:I6uRR8VgOIdIubveOaoay+oJMzk632	intact-crc:63FAD8C3CF731B39|rigid:q8TTisZ3gdCkc/BwKgbnzxjmaZw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H0W0	uniprotkb:A8K9Y5	intact:EBI-2857561|uniprotkb:Q74U91|uniprotkb:Q0WFF6|uniprotkb:A0A380PDB4|uniprotkb:Q7CI92|uniprotkb:A0A384L848	intact:EBI-2809249	psi-mi:a0a2u2h0w0_yerpe(display_long)|uniprotkb:YPO1997(locus name)	psi-mi:a8k9y5_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876612|imex:IM-13779-8425	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR052750|interpro:IPR029058|refseq:WP_002211257.1|refseq:YP_002346982.1	"interpro:IPR049730|interpro:IPR023780|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000330(SNF2-related)|interpro:IPR038718|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016787""(hydrolase activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DP6LxF8YTJKUt3yW/2M2CRKvosU632	rogid:33GOqabqaL4Rbx4rktjcRfgP4zA9606	intact-crc:9FE7D85EFA561895|rigid:0WyZv0gxDyVnc2fT75NMLsC8pCw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6IEG0	uniprotkb:O68779	intact:EBI-2876632|ensembl:ENSP00000339834.4|uniprotkb:Q5THM2|uniprotkb:Q96MK1|uniprotkb:Q5THM1|uniprotkb:Q14C91|uniprotkb:Q5T339|uniprotkb:A8K8P4	intact:EBI-2853455|intact:EBI-2855635|uniprotkb:Q74YF2|uniprotkb:Q7ARB0|uniprotkb:Q7BT13|uniprotkb:A0A3G5L6V4|uniprotkb:A0A1U8QYA4|uniprotkb:A0A0H2W5L4|uniprotkb:Q7CIE2	psi-mi:snr48_human(display_long)|uniprotkb:SNRNP48(gene name)|psi-mi:SNRNP48(display_short)|uniprotkb:C6orf151(gene name synonym)	psi-mi:o68779_yerpe(display_long)|uniprotkb:y1062(gene name)|psi-mi:y1062(display_short)|uniprotkb:ypmt1.80C(gene name synonym)|uniprotkb:ISU59_11670(orf name)|uniprotkb:ISU59_12615(orf name)|uniprotkb:YPMT1.80c(locus name)|uniprotkb:YPO0011(locus name)|uniprotkb:YPO1493(locus name)|uniprotkb:YPO1561(locus name)|uniprotkb:YPO1583(locus name)|uniprotkb:YPO1589(locus name)|uniprotkb:YPO1621(locus name)|uniprotkb:YPO1727(locus name)|uniprotkb:YPO1988(locus name)|uniprotkb:YPO2104(locus name)|uniprotkb:YPO2136(locus name)|uniprotkb:YPO2170(locus name)|uniprotkb:YPO2194(locus name)|uniprotkb:YPO2447(locus name)|uniprotkb:YPO2571(locus name)|uniprotkb:YPO2656(locus name)|uniprotkb:YPO2783(locus name)|uniprotkb:YPO2799(locus name)|uniprotkb:YPO2862(locus name)|uniprotkb:YPO2942(locus name)|uniprotkb:YPO3875(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876642|imex:IM-13779-8424	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168566.13(gene)|ensembl:ENST00000342415.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005689""(U12-type spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0046872""(metal ion binding)|interpro:IPR022776|interpro:IPR036236|interpro:IPR051591|mint:Q6IEG0|rcsb pdb:2VY4|rcsb pdb:2VY5|rcsb pdb:8Y6O|reactome:R-HSA-72165|refseq:NP_689764.3|panther:PTHR21402(orthology-group)"	"refseq:NP_395426.1|refseq:NP_857700.1|interpro:IPR001207(Transposase, mutator type)|refseq:YP_093966.1|refseq:WP_002209743.1|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|refseq:YP_002347531.1|refseq:YP_002345107.1|refseq:YP_002346509.1|refseq:YP_002346575.1|refseq:YP_002346595.1|refseq:YP_002346600.1|refseq:YP_002346632.1|refseq:YP_002346729.1|refseq:YP_002346973.1|refseq:YP_002347085.1|refseq:YP_002347114.1|refseq:YP_002347145.1|refseq:YP_002347167.1|refseq:YP_002347411.1|refseq:YP_002347607.1|refseq:YP_002347730.1|refseq:YP_002347741.1|refseq:YP_002347797.1|refseq:YP_002347869.1|refseq:YP_002348751.1|panther:PTHR33217(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xKzG44rRn2jI0igYZDuk2eP7+Eg9606	rogid:y/++sl3PEsvjk5YqmX2+hc+8JHM632	intact-crc:B18ADE65566D7F9F|rigid:Dyt9j72BhgUxYwlyx3birBPO15g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q9UHQ1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-2876604|uniprotkb:B3KPX2|uniprotkb:K4DI98|intact:EBI-8994327|intact:EBI-4395842|uniprotkb:A6NCJ3|uniprotkb:Q96AY9|uniprotkb:Q9BWC6|ensembl:ENSP00000309899.10|intact:EBI-10964477	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:narf_human(display_long)|uniprotkb:NARF(gene name)|psi-mi:NARF(display_short)|uniprotkb:Iron-only hydrogenase-like protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876601|imex:IM-13779-8423	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:XP_011521843.1|refseq:NP_001033707.1|refseq:NP_001077077.1|refseq:NP_036468.1|refseq:NP_114174.1|refseq:XP_005256397.1|ensembl:ENSG00000141562.19(gene)|ensembl:ENST00000309794.16(transcript)|go:""GO:0005521""(lamin binding)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0031981""(nuclear lumen)|interpro:IPR003149(Iron hydrogenase, small subunit-like)|interpro:IPR004108(Iron hydrogenase, large subunit, C-terminal)|interpro:IPR009016(Iron hydrogenase)|interpro:IPR050340|mint:Q9UHQ1|panther:PTHR11615(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:fjsvsPlOTpCHvHIZ/Px5eC7rJqk9606	intact-crc:6499339C9A54F418|rigid:LLiBgELex4+EG6Vdi54fgrrlreA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UPG8	uniprotkb:Q8ZBM0	intact:EBI-2876622|ensembl:ENSP00000246229.4|uniprotkb:Q92584|uniprotkb:A8K8T5|uniprotkb:E1P5M3	intact:EBI-2840455|uniprotkb:Q0WBQ8	psi-mi:plal2_human(display_long)|uniprotkb:PLAGL2(gene name)|psi-mi:PLAGL2(display_short)|uniprotkb:KIAA0198(gene name synonym)|uniprotkb:Pleiomorphic adenoma-like protein 2(gene name synonym)	psi-mi:clca_yerpe(display_long)|uniprotkb:clcA(gene name)|psi-mi:clcA(display_short)|uniprotkb:eriC(gene name synonym)|uniprotkb:YPO3388(locus name)|uniprotkb:y0800(locus name)|uniprotkb:YP_0297(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876619|imex:IM-13779-8426	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000126003.7(gene)|ensembl:ENST00000246229.5(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0009791""(post-embryonic development)|go:""GO:0034378""(chylomicron assembly)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0046872""(metal ion binding)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_011527165.1|refseq:XP_011527166.1|refseq:NP_002648.1|refseq:XP_005260493.1|panther:PTHR24408(orthology-group)"	"interpro:IPR023861|interpro:IPR014743(Chloride channel, core)|interpro:IPR001807(Chloride channel, voltage gated)|go:""GO:0005247""(voltage-gated chloride channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0015297""(antiporter activity)|refseq:WP_002209364.1|panther:PTHR45711(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ccN33kK/lnKGSE4G3rJ/TvkIEE09606	rogid:WeatLyFsyQ5maYNaNNcig8VtCFY632	intact-crc:018418E7A580AB3F|rigid:JGI3hcTW8mhg/vF6qDRwJbsU7vo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZD91	uniprotkb:Q99613	intact:EBI-2851903|uniprotkb:Q0WDJ3	intact:EBI-353741|uniprotkb:A8K7Z0|ensembl:ENSP00000332604.7|ensembl:ENSP00000378953.1|ensembl:ENSP00000457418.1|ensembl:ENSP00000457963.1|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-25643229|uniprotkb:B4E1D5|uniprotkb:H3BRV0|intact:EBI-11017021	psi-mi:gch1l_yerpe(display_long)|uniprotkb:YPO2697(locus name)|uniprotkb:YP_2501(locus name)|uniprotkb:y1272(locus name)	psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876649|imex:IM-13779-8427	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002354507.1|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|interpro:IPR036069|refseq:YP_002347645.1|panther:PTHR13799(orthology-group)"	"refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|ensembl:ENSG00000184110.15(gene)|ensembl:ENST00000331666.11(transcript)|ensembl:ENST00000395587.5(transcript)|ensembl:ENST00000566501.5(transcript)|ensembl:ENST00000566866.5(transcript)|rcsb pdb:8PJ3|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0043022""(ribosome binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:1902416""(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8RG0|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001273407.1|refseq:NP_001254503.1|dip:DIP-32865N|panther:PTHR13937(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:58ZcDrFPj+OjNZlX9MbsqJHN2vs632	rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606	intact-crc:9FE50027268CD796|rigid:2q53Z5gI5W3sqUV4UrAOosg6YK4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1R4	uniprotkb:Q9H305	intact:EBI-2843814|uniprotkb:Q74PS6	intact:EBI-2876678|ensembl:ENSP00000382508.2|ensembl:ENSP00000454994.1|ensembl:ENSP00000457877.1|ensembl:ENSP00000480842.1|ensembl:ENSP00000488066.1|ensembl:ENSP00000488474.1|uniprotkb:Q9H0Q4|uniprotkb:Q9P112|uniprotkb:Q96ID8|uniprotkb:A8K7M1|uniprotkb:D3DUD6|uniprotkb:B4DFU1|uniprotkb:B4DY75	psi-mi:q8d1r4_yerpe(display_long)|uniprotkb:gltB(gene name)|psi-mi:gltB(display_short)|uniprotkb:y0128(locus name)|uniprotkb:YP_3811(locus name)	psi-mi:cdip1_human(display_long)|uniprotkb:CDIP1(gene name)|psi-mi:CDIP1(display_short)|uniprotkb:C16orf5(gene name synonym)|uniprotkb:CDIP(gene name synonym)|uniprotkb:Cell death involved p53-target(gene name synonym)|uniprotkb:Cell death-inducing protein(gene name synonym)|uniprotkb:LITAF-like protein(gene name synonym)|uniprotkb:LITAFL(gene name synonym)|uniprotkb:Lipopolysaccharide-induced tumor necrosis factor-alpha-like protein(gene name synonym)|uniprotkb:Transmembrane protein I1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876675|imex:IM-13779-8430	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029055|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017932|interpro:IPR002489(Glutamate synthase, alpha subunit, C-terminal)|interpro:IPR002932(Glutamate synthase, central-C)|interpro:IPR006982(Glutamate synthase, central-N)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0015930""(glutamate synthase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051538""(3 iron, 4 sulfur cluster binding)|interpro:IPR036485|interpro:IPR050711"	"ensembl:ENSG00000089486.17(gene)|ensembl:ENSG00000274336.2(gene)|ensembl:ENST00000399599.7(transcript)|ensembl:ENST00000563332.6(transcript)|ensembl:ENST00000567695.6(transcript)|ensembl:ENST00000611166.2(transcript)|ensembl:ENST00000632680.1(transcript)|ensembl:ENST00000632937.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0098560""(cytoplasmic side of late endosome membrane)|go:""GO:0098574""(cytoplasmic side of lysosomal membrane)|interpro:IPR006629(LPS-induced tumor necrosis factor alpha factor)|interpro:IPR037519|mint:Q9H305|refseq:NP_001185984.1|refseq:NP_001185985.1|refseq:NP_001185983.1|refseq:NP_037531.2|panther:PTHR23292(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ffhc+0W6qLx9CoigiaqmB+0w2JQ632	rogid:MFdzIJQo2unruDYEy4jrGglZ7FA9606	intact-crc:A7FE5460B203C651|rigid:8nqvb3QgchJ6XxoKSGQ2Cb6bWYU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKI8	uniprotkb:A8K7X3	intact:EBI-2855532	intact:EBI-2876668	psi-mi:q8cki8_yerpe(display_long)|uniprotkb:NCTC5923_02392(orf name)|uniprotkb:y3427(locus name)	psi-mi:a8k7x3_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876665|imex:IM-13779-8429	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002213742.1	"go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0016020""(membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kFpagl9Qd6b6ImFRX9++a7dnIjA632	rogid:zWk8pt+fKZM4+00tIiShBPLcUwo9606	intact-crc:15AC8A3BE6CED72B|rigid:rWxqAZmq9LAKjyAGsu8BPZ01ZXA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D080	uniprotkb:Q9H305	intact:EBI-2841341	intact:EBI-2876678|ensembl:ENSP00000382508.2|ensembl:ENSP00000454994.1|ensembl:ENSP00000457877.1|ensembl:ENSP00000480842.1|ensembl:ENSP00000488066.1|ensembl:ENSP00000488474.1|uniprotkb:Q9H0Q4|uniprotkb:Q9P112|uniprotkb:Q96ID8|uniprotkb:A8K7M1|uniprotkb:D3DUD6|uniprotkb:B4DFU1|uniprotkb:B4DY75	psi-mi:q8d080_yerpe(display_long)|uniprotkb:y2613(locus name)	psi-mi:cdip1_human(display_long)|uniprotkb:CDIP1(gene name)|psi-mi:CDIP1(display_short)|uniprotkb:C16orf5(gene name synonym)|uniprotkb:CDIP(gene name synonym)|uniprotkb:Cell death involved p53-target(gene name synonym)|uniprotkb:Cell death-inducing protein(gene name synonym)|uniprotkb:LITAF-like protein(gene name synonym)|uniprotkb:LITAFL(gene name synonym)|uniprotkb:Lipopolysaccharide-induced tumor necrosis factor-alpha-like protein(gene name synonym)|uniprotkb:Transmembrane protein I1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876690|imex:IM-13779-8428	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001670(Iron-containing alcohol dehydrogenase)|interpro:IPR018211|go:""GO:0016614""(oxidoreductase activity, acting on CH-OH group of donors)|go:""GO:0046872""(metal ion binding)|interpro:IPR016205(Glycerol dehydrogenase)"	"ensembl:ENSG00000089486.17(gene)|ensembl:ENSG00000274336.2(gene)|ensembl:ENST00000399599.7(transcript)|ensembl:ENST00000563332.6(transcript)|ensembl:ENST00000567695.6(transcript)|ensembl:ENST00000611166.2(transcript)|ensembl:ENST00000632680.1(transcript)|ensembl:ENST00000632937.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0098560""(cytoplasmic side of late endosome membrane)|go:""GO:0098574""(cytoplasmic side of lysosomal membrane)|interpro:IPR006629(LPS-induced tumor necrosis factor alpha factor)|interpro:IPR037519|mint:Q9H305|refseq:NP_001185984.1|refseq:NP_001185985.1|refseq:NP_001185983.1|refseq:NP_037531.2|panther:PTHR23292(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lUUIJTo0TaVgDeJFI9qxAhwSaLs632	rogid:MFdzIJQo2unruDYEy4jrGglZ7FA9606	intact-crc:DE092560B3655A33|rigid:mwHwLekvnHfCvwA4ZeiFkBHaMww	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75648	uniprotkb:Q0WJW6	intact:EBI-2876757|uniprotkb:Q6ICC3|uniprotkb:Q5W9C8|uniprotkb:Q66K31|uniprotkb:Q9NWC1|uniprotkb:Q05C99|uniprotkb:A8K3U7|ensembl:ENSP00000496496.1	intact:EBI-2860690|uniprotkb:Q74XD4|uniprotkb:Q7CKN1|uniprotkb:A0A3N4AXG1|uniprotkb:A0A0H2W329	psi-mi:mtu1_human(display_long)|uniprotkb:TRMU(gene name)|psi-mi:TRMU(display_short)|uniprotkb:MTU1(gene name synonym)|uniprotkb:TRMT1(gene name synonym)|uniprotkb:MTO2 homolog(gene name synonym)	psi-mi:q0wjw6_yerpe(display_long)|uniprotkb:b4079(gene name)|psi-mi:b4079(display_short)|uniprotkb:fdhF(gene name synonym)|uniprotkb:YPO0344(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876754|imex:IM-13779-8435	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100416.15(gene)|ensembl:ENST00000645190.1(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002143""(tRNA wobble position uridine thiolation)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0061708""(tRNA-5-taurinomethyluridine 2-sulfurtransferase)|interpro:IPR004506(""tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase"")|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023382|interpro:IPR046884|interpro:IPR046885|reactome:R-HSA-6787450|refseq:NP_001269712.1|refseq:NP_001269713.1|refseq:NP_001269714.1|refseq:NP_060476.2|efo:""Orphanet:217371""|efo:""Orphanet:254864""|efo:""Orphanet:90641""|panther:PTHR11933(orthology-group)"	"interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006478(Formate dehydrogenase, alpha subunit)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR027467|refseq:WP_002209120.1|interpro:IPR050123|go:""GO:0008863""(""formate dehydrogenase (NAD+) activity"")|go:""GO:0015942""(formate metabolic process)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:1990204""(oxidoreductase complex)|interpro:IPR041924|refseq:YP_002345422.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VCKwfCP+XC6sqY+3CJJHmKSbaJE9606	rogid:k6dXgc/93CsEB3BuTI7fZvAR+eo632	intact-crc:4C3EB166D7489C7B|rigid:0gTBG/LIxawNE67J9qvz26BOzCE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YLY5	uniprotkb:P25106	intact:EBI-2840998|uniprotkb:A0A384LAN6|uniprotkb:Q74Y20|uniprotkb:Q7CFW0|uniprotkb:Q0WKE1	intact:EBI-1965291|uniprotkb:A8K6J4|ensembl:ENSP00000272928.3|intact:EBI-2839036|uniprotkb:Q53RV4|uniprotkb:Q8NE10|uniprotkb:Q92986|uniprotkb:Q92938	psi-mi:a0a5p8yly5_yerpe(display_long)|uniprotkb:nirB(gene name)|psi-mi:nirB(display_short)|uniprotkb:YPO0161(locus name)	psi-mi:ackr3_human(display_long)|uniprotkb:ACKR3(gene name)|psi-mi:ACKR3(display_short)|uniprotkb:C-X-C chemokine receptor type 7(gene name synonym)|uniprotkb:CMKOR1(gene name synonym)|uniprotkb:CXCR7(gene name synonym)|uniprotkb:Chemokine orphan receptor 1(gene name synonym)|uniprotkb:G-protein coupled receptor 159(gene name synonym)|uniprotkb:G-protein coupled receptor RDC1 homolog(gene name synonym)|uniprotkb:GPR159(gene name synonym)|uniprotkb:RDC1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876717|imex:IM-13779-8434	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002345247.1|interpro:IPR007419(BFD-like [2Fe-2S]-binding region)|interpro:IPR005117(Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like)|interpro:IPR012744(""Nitrite reductase [NAD(P)H] large subunit, NirB"")|interpro:IPR017121(""Nitrite reductase [NAD(P)H], large subunit"")|interpro:IPR006067(Nitrite and sulphite reductase 4Fe-4S region)|interpro:IPR006066(Nitrite and sulphite reductase iron-sulphur/siroheme-binding site)|interpro:IPR023753|interpro:IPR041575|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|go:""GO:0020037""(heme binding)|go:""GO:0042128""(nitrate assimilation)|go:""GO:0046872""(metal ion binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0050661""(NADP binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0098809""(nitrite reductase activity)|refseq:WP_002208886.1|interpro:IPR036136|interpro:IPR036188|interpro:IPR041854|interpro:IPR052034|interpro:IPR045854|panther:PTHR43809(orthology-group)"	"ensembl:ENSG00000144476.6(gene)|ensembl:ENST00000272928.4(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016493""(C-C chemokine receptor activity)|go:""GO:0016494""(C-X-C chemokine receptor activity)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019957""(C-C chemokine binding)|go:""GO:0019958""(C-X-C chemokine binding)|go:""GO:0021557""(oculomotor nerve development)|go:""GO:0031623""(receptor internalization)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055037""(recycling endosome)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0070098""(chemokine-mediated signaling pathway)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:1905322""(positive regulation of mesenchymal stem cell migration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001416(RDC1 orphan receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR047143|mint:P25106|rcsb pdb:6K3F|rcsb pdb:7SK3|rcsb pdb:7SK4|rcsb pdb:7SK5|rcsb pdb:7SK6|rcsb pdb:7SK7|rcsb pdb:7SK8|rcsb pdb:7SK9|reactome:R-HSA-380108|reactome:R-HSA-418594|refseq:NP_064707.1|panther:PTHR10489(orthology-group)|refseq:XP_005246154.1|refseq:XP_005246155.1|refseq:XP_016860005.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6u3Rf93p+0SPTDFZ4PpmLjcphzY632	rogid:pELQ/+pDL3eQ+abxFpwYRKBPwrI9606	intact-crc:A2BD32A3364206C5|rigid:UJ86yFagHPAvgiQkxhCbdA8a4oc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3A2	uniprotkb:Q8ZGZ1	intact:EBI-2876697|ensembl:ENSP00000362105.4|uniprotkb:Q9BS98|uniprotkb:Q9NS31|uniprotkb:Q5VT93|intact:EBI-2963233|uniprotkb:A8K785|uniprotkb:D3DPT7|uniprotkb:B4DJC6	intact:EBI-2876705|uniprotkb:Q0WHS1	psi-mi:utp11_human(display_long)|uniprotkb:HDCMB12P(orf name)|uniprotkb:UTP11(gene name)|psi-mi:UTP11(display_short)|uniprotkb:UTP11-like protein(gene name synonym)|uniprotkb:UTP11L(gene name synonym)|uniprotkb:CGI-94(orf name)	psi-mi:tolb_yerpe(display_long)|uniprotkb:tolB(gene name)|psi-mi:tolB(display_short)|uniprotkb:YPO1124(locus name)|uniprotkb:y3055(locus name)|uniprotkb:YP_1032(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876710|imex:IM-13779-8431	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000183520.12(gene)|ensembl:ENST00000373014.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006364""(rRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0032040""(small-subunit processome)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0043065""(positive regulation of apoptotic process)|interpro:IPR007144(Small-subunit processome, Utp11)|mint:Q9Y3A2|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_057121.2|panther:PTHR12838(orthology-group)"	"go:""GO:0017038""(protein import)|go:""GO:0042597""(periplasmic space)|go:""GO:0051301""(cell division)|interpro:IPR011659(WD40-like Beta Propeller)|interpro:IPR014167(Tol-Pal system beta propeller repeat, TolB)|interpro:IPR007195(TolB, N-terminal)|rcsb pdb:4PWZ|rcsb pdb:4R40|refseq:WP_002210738.1|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|refseq:YP_002346167.1|panther:PTHR42972(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JTS/jMbRZE3NifB95Nqh0foDUKI9606	rogid:wzU4pNHQUqobOdeWRSEqA5Xjzcw632	intact-crc:2B1A198D83698DAA|rigid:2sNab4YBhjdeJuAI62dnNogVyUI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H7R5	uniprotkb:A0A2S9PFE9	intact:EBI-2876745|ensembl:ENSP00000379702.2|ensembl:ENSP00000498600.1|uniprotkb:A8K5T8|intact:EBI-18279043	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	psi-mi:zn665_human(display_long)|uniprotkb:ZNF665(gene name)|psi-mi:ZNF665(display_short)|uniprotkb:ZFP160L(gene name synonym)|uniprotkb:Zinc finger protein 160-like(gene name synonym)	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876742|imex:IM-13779-8433	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000197497.11(gene)|ensembl:ENST00000396424.5(transcript)|ensembl:ENST00000650736.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR050331|mint:Q9H7R5|reactome:R-HSA-212436|refseq:XP_005259323.1|refseq:NP_079009.3|panther:PTHR24377(orthology-group)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9/DgjrbkoV2+bFmuLkmFc+msvfM9606	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	intact-crc:D96B01D220C3F8E9|rigid:uqt6PDICYPsOfVHUXeDzNqBuJgs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N5D6	uniprotkb:Q8CZL7	intact:EBI-2876727|ensembl:ENSP00000361110.3|uniprotkb:B2RA95|uniprotkb:Q5T7U9|uniprotkb:Q45F07|uniprotkb:Q5T7V1|uniprotkb:Q8N2K4|uniprotkb:Q9UKI5|uniprotkb:A8K633|uniprotkb:B7Z8S5	intact:EBI-2845506	psi-mi:gbgt1_human(display_long)|uniprotkb:GBGT1(gene name)|psi-mi:GBGT1(display_short)|uniprotkb:Forssman glycolipid synthase-like protein(gene name synonym)|uniprotkb:UNQ2513/PRO6002(orf name)	psi-mi:q8czl7_yerpe(display_long)|uniprotkb:dppD(gene name)|psi-mi:dppD(display_short)|uniprotkb:y3829(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876724|imex:IM-13779-8432	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269558.1|ensembl:ENSG00000148288.13(gene)|ensembl:ENST00000372040.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006486""(protein glycosylation)|go:""GO:0009247""(glycolipid biosynthetic process)|go:""GO:0030259""(lipid glycosylation)|go:""GO:0031982""(vesicle)|go:""GO:0046872""(metal ion binding)|go:""GO:0047277""(globoside alpha-N-acetylgalactosaminyltransferase activity)|interpro:IPR005076(Glycosyl transferase, family 6)|interpro:IPR029044|refseq:NP_068836.2|refseq:NP_001275501.1|refseq:NP_001275502.1|refseq:NP_001269561.1|panther:PTHR10462(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013563(Oligopeptide/dipeptide ABC transporter, C-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015833""(peptide transport)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR050388"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ptK726yCFnJBsYmbAf2hQER5VqM9606	rogid:Gev4OfphwfDSbN4FiC5eZnSGwBM632	intact-crc:1E1E1B1EE9434CDB|rigid:m/K95SXiygpUwuckkH5MYzXw88Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O68779	uniprotkb:Q8IYB8	intact:EBI-2853455|intact:EBI-2855635|uniprotkb:Q74YF2|uniprotkb:Q7ARB0|uniprotkb:Q7BT13|uniprotkb:A0A3G5L6V4|uniprotkb:A0A1U8QYA4|uniprotkb:A0A0H2W5L4|uniprotkb:Q7CIE2	intact:EBI-2876787|ensembl:ENSP00000352678.4|uniprotkb:O43630|intact:EBI-3205796|uniprotkb:A8K301	psi-mi:o68779_yerpe(display_long)|uniprotkb:y1062(gene name)|psi-mi:y1062(display_short)|uniprotkb:ypmt1.80C(gene name synonym)|uniprotkb:ISU59_11670(orf name)|uniprotkb:ISU59_12615(orf name)|uniprotkb:YPMT1.80c(locus name)|uniprotkb:YPO0011(locus name)|uniprotkb:YPO1493(locus name)|uniprotkb:YPO1561(locus name)|uniprotkb:YPO1583(locus name)|uniprotkb:YPO1589(locus name)|uniprotkb:YPO1621(locus name)|uniprotkb:YPO1727(locus name)|uniprotkb:YPO1988(locus name)|uniprotkb:YPO2104(locus name)|uniprotkb:YPO2136(locus name)|uniprotkb:YPO2170(locus name)|uniprotkb:YPO2194(locus name)|uniprotkb:YPO2447(locus name)|uniprotkb:YPO2571(locus name)|uniprotkb:YPO2656(locus name)|uniprotkb:YPO2783(locus name)|uniprotkb:YPO2799(locus name)|uniprotkb:YPO2862(locus name)|uniprotkb:YPO2942(locus name)|uniprotkb:YPO3875(locus name)	psi-mi:suv3_human(display_long)|uniprotkb:SUPV3L1(gene name)|psi-mi:SUPV3L1(display_short)|uniprotkb:SUV3(gene name synonym)|uniprotkb:Suppressor of var1 3-like protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876784|imex:IM-13779-8436	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395426.1|refseq:NP_857700.1|interpro:IPR001207(Transposase, mutator type)|refseq:YP_093966.1|refseq:WP_002209743.1|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|refseq:YP_002347531.1|refseq:YP_002345107.1|refseq:YP_002346509.1|refseq:YP_002346575.1|refseq:YP_002346595.1|refseq:YP_002346600.1|refseq:YP_002346632.1|refseq:YP_002346729.1|refseq:YP_002346973.1|refseq:YP_002347085.1|refseq:YP_002347114.1|refseq:YP_002347145.1|refseq:YP_002347167.1|refseq:YP_002347411.1|refseq:YP_002347607.1|refseq:YP_002347730.1|refseq:YP_002347741.1|refseq:YP_002347797.1|refseq:YP_002347869.1|refseq:YP_002348751.1|panther:PTHR33217(orthology-group)"	"ensembl:ENSG00000156502.14(gene)|ensembl:ENST00000359655.9(transcript)|go:""GO:0000957""(mitochondrial RNA catabolic process)|go:""GO:0000958""(mitochondrial mRNA catabolic process)|go:""GO:0000962""(positive regulation of mitochondrial RNA catabolic process)|go:""GO:0000965""(mitochondrial RNA 3'-end processing)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006310""(DNA recombination)|go:""GO:0006401""(RNA catabolic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0034458""(3'-5' RNA helicase activity)|go:""GO:0035945""(mitochondrial ncRNA surveillance)|go:""GO:0035946""(mitochondrial mRNA surveillance)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045025""(mitochondrial degradosome)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:2000827""(mitochondrial RNA surveillance)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022192|interpro:IPR027417|interpro:IPR041082|interpro:IPR041453|interpro:IPR044774|interpro:IPR050699|interpro:IPR055206|mint:Q8IYB8|rcsb pdb:3RC3|rcsb pdb:3RC8|rcsb pdb:7W1R|reactome:R-HSA-9836573|refseq:NP_003162.2|refseq:NP_001288612.1|panther:PTHR12131(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y/++sl3PEsvjk5YqmX2+hc+8JHM632	rogid:XmEujscj0Njj3Un62nLFTzgqr6Y9606	intact-crc:D527637454813B31|rigid:Shqxal3smYUteMsIvW+BXSvsSwM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14914	uniprotkb:A0A5P8YEZ8	intact:EBI-2876800|ensembl:ENSP00000311572.5|ensembl:ENSP00000385763.2|uniprotkb:Q9H1X6|uniprotkb:Q8IYQ0|uniprotkb:A8K0N2|uniprotkb:B4DPK3|uniprotkb:F5GY50	intact:EBI-2845602|uniprotkb:Q74U77|uniprotkb:Q0WFE2|uniprotkb:Q7CIA0|uniprotkb:A0A384LA14	"psi-mi:ptgr1_human(display_long)|uniprotkb:PTGR1(gene name)|psi-mi:PTGR1(display_short)|uniprotkb:LTB4DH(gene name synonym)|uniprotkb:15-oxoprostaglandin 13-reductase(gene name synonym)|uniprotkb:Dithiolethione-inducible gene 1 protein(gene name synonym)|uniprotkb:Leukotriene B4 12-hydroxydehydrogenase(gene name synonym)|uniprotkb:""NAD(P)H-dependent alkenal/one oxidoreductase""(gene name synonym)"	psi-mi:a0a5p8yez8_yerpe(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:YPO2010(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876797|imex:IM-13779-8437	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106853.20(gene)|ensembl:ENST00000309195.9(transcript)|ensembl:ENST00000407693.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0006691""(leukotriene metabolic process)|go:""GO:0006693""(prostaglandin metabolic process)|go:""GO:0035798""(""2-alkenal reductase (NADPH) activity"")|go:""GO:0036102""(leukotriene B4 metabolic process)|go:""GO:0036185""(13-lipoxin reductase activity)|go:""GO:0047522""(""15-oxoprostaglandin 13-oxidase [NAD(P)+] activity"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0097257""(leukotriene B4 12-hydroxy dehydrogenase activity)|go:""GO:2001302""(lipoxin A4 metabolic process)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR014190(Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase)|interpro:IPR020843|interpro:IPR036291|interpro:IPR041694|interpro:IPR045010|rcsb pdb:1ZSV|rcsb pdb:2Y05|reactome:R-HSA-2142691|reactome:R-HSA-2142700|refseq:NP_001139580.1|refseq:NP_001139581.1|refseq:NP_036344.2|panther:PTHR43205(orthology-group)"	"interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|interpro:IPR004095(TGS)|interpro:IPR031167|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0043023""(ribosomal large subunit binding)|interpro:IPR041706|refseq:WP_002211245.1|refseq:YP_002346996.1|panther:PTHR23305(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t+By3HtbHpy86Labvsz5of3uHGA9606	rogid:3iq6UNiclH9s/Tvlmo7cFMlj60w632	intact-crc:D4820C1F94BA675E|rigid:GHRkAvIvyL2X1EXeTtho/jaAw0c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46359	uniprotkb:Q92520	intact:EBI-2844956|uniprotkb:Q0WFP1	intact:EBI-2876774|ensembl:ENSP00000353025.3|uniprotkb:A6NDN2|intact:EBI-3248577|uniprotkb:A8K3R7	psi-mi:fyua_yerpe(display_long)|uniprotkb:fyuA(gene name)|psi-mi:fyuA(display_short)|uniprotkb:psn(gene name synonym)|uniprotkb:IRPC(gene name synonym)|uniprotkb:YPO1906(locus name)|uniprotkb:y2404(locus name)|uniprotkb:YP_1649(locus name)	psi-mi:fam3c_human(display_long)|uniprotkb:FAM3C(gene name)|psi-mi:FAM3C(display_short)|uniprotkb:ILEI(gene name synonym)|uniprotkb:Interleukin-like EMT inducer(gene name synonym)|uniprotkb:GS3786(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876771|imex:IM-13779-8438	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|rcsb pdb:4EPA|go:""GO:0009279""(cell outer membrane)|go:""GO:0015344""(siderophore uptake transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0044718""(siderophore transmembrane transport)|refseq:WP_002212885.1|interpro:IPR036942|interpro:IPR039426|refseq:YP_002346897.1|panther:PTHR30069(orthology-group)"	"ensembl:ENSG00000196937.11(gene)|ensembl:ENST00000359943.8(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0031089""(platelet dense granule lumen)|go:""GO:0070062""(extracellular exosome)|interpro:IPR039220|interpro:IPR039475|interpro:IPR039477|mint:Q92520|rcsb pdb:5LC2|reactome:R-HSA-114608|refseq:XP_011514038.1|refseq:XP_011514039.1|refseq:NP_001035109.1|refseq:NP_055703.1|panther:PTHR14592(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sl/8Ppm/ZorktNWh6kbdsQhE1JA632	rogid:hDXcGLgnq0vUR8ZeiCt1NCXtrBY9606	intact-crc:81C7A35E6BAB5998|rigid:31JrSOTPKGi3V2qB41YM7/D557g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B6L4	uniprotkb:A8K0D8	intact:EBI-2843521|uniprotkb:Q74R92|uniprotkb:Q0WAE3|uniprotkb:Q7CKZ2|uniprotkb:A0A384KL30	intact:EBI-2813571	psi-mi:a0a3n4b6l4_yerpe(display_long)|uniprotkb:psuA(gene name synonym)|uniprotkb:rnsC(gene name synonym)|uniprotkb:sbaA(gene name synonym)|uniprotkb:tsu(gene name synonym)|uniprotkb:ATP-dependent helicase Rho(gene name synonym)|uniprotkb:rho(gene name synonym)|uniprotkb:nitA(gene name)|psi-mi:nitA(display_short)|uniprotkb:YPO3867(locus name)	psi-mi:a8k0d8_human(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876811|imex:IM-13779-8439	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR011112(Rho termination factor, N-terminal)|interpro:IPR011113(Rho termination factor, RNA-binding)|interpro:IPR004665(Transcription termination factor Rho)|interpro:IPR027417|go:""GO:0003723""(RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002211989.1|interpro:IPR036269|interpro:IPR041703|refseq:YP_002348745.1|panther:PTHR46425(orthology-group)"	"interpro:IPR017981|interpro:IPR008078(GPCR, family 2, Ig-hepta receptor)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR017983|interpro:IPR000203(GPS)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR000082(SEA)|interpro:IPR051587|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|interpro:IPR036179|interpro:IPR036364|interpro:IPR046338"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:d6NkDZjvNCwgkhXxhvckAvDrcJE632	rogid:Bv0hLsZG9S4nZKcl/hqUZL6wE2w9606	intact-crc:72582C0924FE2852|rigid:D9+P5HscpnGLdZZbTSpBLvSjvWk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YBX0	uniprotkb:O00182	intact:EBI-2855210|uniprotkb:Q74QT9|uniprotkb:A0A2U2H4E7|uniprotkb:Q0WA14|uniprotkb:Q7CG21|uniprotkb:A0A384KQZ3	intact:EBI-1045193|uniprotkb:O14532|uniprotkb:O75028|uniprotkb:Q9NQ58|uniprotkb:Q3B8N1|intact:EBI-2799360|uniprotkb:A7VJG6|uniprotkb:Q53FQ0|uniprotkb:F8W9W4|uniprotkb:Q8WYQ7|ensembl:ENSP00000378856.2	psi-mi:a0a5p8ybx0_yerpe(display_long)|uniprotkb:YPO4006(locus name)	psi-mi:leg9_human(display_long)|uniprotkb:Tumor antigen HOM-HD-21(gene name synonym)|uniprotkb:Ecalectin(gene name synonym)|uniprotkb:LGALS9(gene name)|psi-mi:LGALS9(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876842|imex:IM-13779-8443	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002224153.1|interpro:IPR010069(Adhesin HecA 20-residue repeat x2)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|refseq:YP_002348874.1	"refseq:NP_002299.2|refseq:NP_033665.1|refseq:XP_006721955.1|refseq:XP_006721958.1|refseq:NP_001317092.1|refseq:XP_016880112.1|ensembl:ENSG00000168961.17(gene)|ensembl:ENST00000395473.7(transcript)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0005534""(galactose binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007565""(female pregnancy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016936""(galactoside binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032834""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043305""(negative regulation of mast cell degranulation)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048030""(disaccharide binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070241""(positive regulation of activated T cell autonomous cell death)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071636""(positive regulation of transforming growth factor beta production)|go:""GO:0071639""(positive regulation of monocyte chemotactic protein-1 production)|go:""GO:0098586""(cellular response to virus)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:2000510""(positive regulation of dendritic cell chemotaxis)|go:""GO:2000562""(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000563""(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000670""(positive regulation of dendritic cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001190""(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001200""(positive regulation of dendritic cell differentiation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:O00182|rcsb pdb:2EAK|rcsb pdb:2EAL|rcsb pdb:2YY1|rcsb pdb:2ZHK|rcsb pdb:2ZHL|rcsb pdb:2ZHM|rcsb pdb:2ZHN|rcsb pdb:3LSD|rcsb pdb:3LSE|rcsb pdb:3NV1|rcsb pdb:3NV2|rcsb pdb:3NV3|rcsb pdb:3NV4|rcsb pdb:3WLU|rcsb pdb:3WV6|reactome:R-HSA-451927|panther:PTHR11346(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:e8wUu6C2TX/Ya1F6JLXvZVWtub8632	rogid:v64u66mEVbUV0bRx1LgUftidZDg9606	intact-crc:5AA84C5F30817B72|rigid:8D03c/W/YPHrQLzmo8pjkySZ1KI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00182	uniprotkb:Q8CZY7	intact:EBI-1045193|uniprotkb:O14532|uniprotkb:O75028|uniprotkb:Q9NQ58|uniprotkb:Q3B8N1|intact:EBI-2799360|uniprotkb:A7VJG6|uniprotkb:Q53FQ0|uniprotkb:F8W9W4|uniprotkb:Q8WYQ7|ensembl:ENSP00000378856.2	intact:EBI-2842279|uniprotkb:Q0WI10|uniprotkb:Q8ZH74	psi-mi:leg9_human(display_long)|uniprotkb:Tumor antigen HOM-HD-21(gene name synonym)|uniprotkb:Ecalectin(gene name synonym)|uniprotkb:LGALS9(gene name)|psi-mi:LGALS9(display_short)	psi-mi:sydp_yerpe(display_long)|uniprotkb:syd(gene name)|psi-mi:syd(display_short)|uniprotkb:YPO1035(locus name)|uniprotkb:y3146(locus name)|uniprotkb:YP_2816(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876818|imex:IM-13779-8442	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002299.2|refseq:NP_033665.1|refseq:XP_006721955.1|refseq:XP_006721958.1|refseq:NP_001317092.1|refseq:XP_016880112.1|ensembl:ENSG00000168961.17(gene)|ensembl:ENST00000395473.7(transcript)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0005534""(galactose binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007565""(female pregnancy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016936""(galactoside binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032834""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043305""(negative regulation of mast cell degranulation)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048030""(disaccharide binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070241""(positive regulation of activated T cell autonomous cell death)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071636""(positive regulation of transforming growth factor beta production)|go:""GO:0071639""(positive regulation of monocyte chemotactic protein-1 production)|go:""GO:0098586""(cellular response to virus)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:2000510""(positive regulation of dendritic cell chemotaxis)|go:""GO:2000562""(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000563""(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000670""(positive regulation of dendritic cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001190""(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001200""(positive regulation of dendritic cell differentiation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:O00182|rcsb pdb:2EAK|rcsb pdb:2EAL|rcsb pdb:2YY1|rcsb pdb:2ZHK|rcsb pdb:2ZHL|rcsb pdb:2ZHM|rcsb pdb:2ZHN|rcsb pdb:3LSD|rcsb pdb:3LSE|rcsb pdb:3NV1|rcsb pdb:3NV2|rcsb pdb:3NV3|rcsb pdb:3NV4|rcsb pdb:3WLU|rcsb pdb:3WV6|reactome:R-HSA-451927|panther:PTHR11346(orthology-group)"	"interpro:IPR009948(Syd)|interpro:IPR038228|go:""GO:0009898""(cytoplasmic side of plasma membrane)|refseq:WP_002212123.1|refseq:YP_002346078.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v64u66mEVbUV0bRx1LgUftidZDg9606	rogid:MC0GRav9hd62E9fkiCF0MQ5eBt4632	intact-crc:7ECEAA4E6CF0D466|rigid:f39S54XMgzDoyqMBbmP7XjcFLYQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZH4	uniprotkb:O00182	intact:EBI-2854937|uniprotkb:Q74QQ7	intact:EBI-1045193|uniprotkb:O14532|uniprotkb:O75028|uniprotkb:Q9NQ58|uniprotkb:Q3B8N1|intact:EBI-2799360|uniprotkb:A7VJG6|uniprotkb:Q53FQ0|uniprotkb:F8W9W4|uniprotkb:Q8WYQ7|ensembl:ENSP00000378856.2	psi-mi:q8czh4_yerpe(display_long)|uniprotkb:fimD7(gene name)|psi-mi:fimD7(display_short)|uniprotkb:YP_3405(locus name)|uniprotkb:y4062(locus name)	psi-mi:leg9_human(display_long)|uniprotkb:Tumor antigen HOM-HD-21(gene name synonym)|uniprotkb:Ecalectin(gene name synonym)|uniprotkb:LGALS9(gene name)|psi-mi:LGALS9(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876825|imex:IM-13779-8440	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR018030|interpro:IPR025885|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR037224|refseq:WP_002228722.1"	"refseq:NP_002299.2|refseq:NP_033665.1|refseq:XP_006721955.1|refseq:XP_006721958.1|refseq:NP_001317092.1|refseq:XP_016880112.1|ensembl:ENSG00000168961.17(gene)|ensembl:ENST00000395473.7(transcript)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0005534""(galactose binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007565""(female pregnancy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016936""(galactoside binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032834""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043305""(negative regulation of mast cell degranulation)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048030""(disaccharide binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070241""(positive regulation of activated T cell autonomous cell death)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071636""(positive regulation of transforming growth factor beta production)|go:""GO:0071639""(positive regulation of monocyte chemotactic protein-1 production)|go:""GO:0098586""(cellular response to virus)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:2000510""(positive regulation of dendritic cell chemotaxis)|go:""GO:2000562""(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000563""(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000670""(positive regulation of dendritic cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001190""(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001200""(positive regulation of dendritic cell differentiation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:O00182|rcsb pdb:2EAK|rcsb pdb:2EAL|rcsb pdb:2YY1|rcsb pdb:2ZHK|rcsb pdb:2ZHL|rcsb pdb:2ZHM|rcsb pdb:2ZHN|rcsb pdb:3LSD|rcsb pdb:3LSE|rcsb pdb:3NV1|rcsb pdb:3NV2|rcsb pdb:3NV3|rcsb pdb:3NV4|rcsb pdb:3WLU|rcsb pdb:3WV6|reactome:R-HSA-451927|panther:PTHR11346(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ShSR+MjoonLHZI8K/Cpx+R6F7DA632	rogid:v64u66mEVbUV0bRx1LgUftidZDg9606	intact-crc:37AFAA4E6C1046E5|rigid:tJTXDmAt3rj7evx2/Nf62BKJRW0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00182	uniprotkb:A0A5P8YHJ8	intact:EBI-1045193|uniprotkb:O14532|uniprotkb:O75028|uniprotkb:Q9NQ58|uniprotkb:Q3B8N1|intact:EBI-2799360|uniprotkb:A7VJG6|uniprotkb:Q53FQ0|uniprotkb:F8W9W4|uniprotkb:Q8WYQ7|ensembl:ENSP00000378856.2	intact:EBI-2876835|uniprotkb:Q0WCL9|uniprotkb:Q7CJI6	psi-mi:leg9_human(display_long)|uniprotkb:Tumor antigen HOM-HD-21(gene name synonym)|uniprotkb:Ecalectin(gene name synonym)|uniprotkb:LGALS9(gene name)|psi-mi:LGALS9(display_short)	psi-mi:a0a5p8yhj8_yerpe(display_long)|uniprotkb:YPO3049(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876832|imex:IM-13779-8441	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002299.2|refseq:NP_033665.1|refseq:XP_006721955.1|refseq:XP_006721958.1|refseq:NP_001317092.1|refseq:XP_016880112.1|ensembl:ENSG00000168961.17(gene)|ensembl:ENST00000395473.7(transcript)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0005534""(galactose binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007565""(female pregnancy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016936""(galactoside binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032834""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043305""(negative regulation of mast cell degranulation)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048030""(disaccharide binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070241""(positive regulation of activated T cell autonomous cell death)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071636""(positive regulation of transforming growth factor beta production)|go:""GO:0071639""(positive regulation of monocyte chemotactic protein-1 production)|go:""GO:0098586""(cellular response to virus)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:2000510""(positive regulation of dendritic cell chemotaxis)|go:""GO:2000562""(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000563""(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000670""(positive regulation of dendritic cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001190""(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001200""(positive regulation of dendritic cell differentiation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:O00182|rcsb pdb:2EAK|rcsb pdb:2EAL|rcsb pdb:2YY1|rcsb pdb:2ZHK|rcsb pdb:2ZHL|rcsb pdb:2ZHM|rcsb pdb:2ZHN|rcsb pdb:3LSD|rcsb pdb:3LSE|rcsb pdb:3NV1|rcsb pdb:3NV2|rcsb pdb:3NV3|rcsb pdb:3NV4|rcsb pdb:3WLU|rcsb pdb:3WV6|reactome:R-HSA-451927|panther:PTHR11346(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_002208545.1|interpro:IPR035906|refseq:YP_002347969.1|panther:PTHR43357(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v64u66mEVbUV0bRx1LgUftidZDg9606	rogid:dM1xttxHNLJKwmHlMqAUPynfImI632	intact-crc:E2BC1BBEAC1C7898|rigid:4nzYFBNFZ+hcDjBo8AFJ39FFayM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0P1	uniprotkb:O00182	intact:EBI-2856506|uniprotkb:Q8ZFL9|uniprotkb:Q0WGA3	intact:EBI-1045193|uniprotkb:O14532|uniprotkb:O75028|uniprotkb:Q9NQ58|uniprotkb:Q3B8N1|intact:EBI-2799360|uniprotkb:A7VJG6|uniprotkb:Q53FQ0|uniprotkb:F8W9W4|uniprotkb:Q8WYQ7|ensembl:ENSP00000378856.2	psi-mi:chey_yerpe(display_long)|uniprotkb:cheY(gene name)|psi-mi:cheY(display_short)|uniprotkb:YPO1680(locus name)|uniprotkb:y1842(locus name)|uniprotkb:YP_1810(locus name)	psi-mi:leg9_human(display_long)|uniprotkb:Tumor antigen HOM-HD-21(gene name synonym)|uniprotkb:Ecalectin(gene name synonym)|uniprotkb:LGALS9(gene name)|psi-mi:LGALS9(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876856|imex:IM-13779-8444	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q8D0P1|interpro:IPR011006(CheY-like)|interpro:IPR001789(Signal transduction response regulator, receiver region)|refseq:WP_002210873.1|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|interpro:IPR052048|refseq:YP_002346685.1|panther:PTHR43228(orthology-group)"	"refseq:NP_002299.2|refseq:NP_033665.1|refseq:XP_006721955.1|refseq:XP_006721958.1|refseq:NP_001317092.1|refseq:XP_016880112.1|ensembl:ENSG00000168961.17(gene)|ensembl:ENST00000395473.7(transcript)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0005534""(galactose binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007565""(female pregnancy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016936""(galactoside binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032834""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043305""(negative regulation of mast cell degranulation)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048030""(disaccharide binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070241""(positive regulation of activated T cell autonomous cell death)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071636""(positive regulation of transforming growth factor beta production)|go:""GO:0071639""(positive regulation of monocyte chemotactic protein-1 production)|go:""GO:0098586""(cellular response to virus)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:2000510""(positive regulation of dendritic cell chemotaxis)|go:""GO:2000562""(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000563""(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000670""(positive regulation of dendritic cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001190""(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001200""(positive regulation of dendritic cell differentiation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:O00182|rcsb pdb:2EAK|rcsb pdb:2EAL|rcsb pdb:2YY1|rcsb pdb:2ZHK|rcsb pdb:2ZHL|rcsb pdb:2ZHM|rcsb pdb:2ZHN|rcsb pdb:3LSD|rcsb pdb:3LSE|rcsb pdb:3NV1|rcsb pdb:3NV2|rcsb pdb:3NV3|rcsb pdb:3NV4|rcsb pdb:3WLU|rcsb pdb:3WV6|reactome:R-HSA-451927|panther:PTHR11346(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wf5r24m07Zgglm31fBnlvBt1VVY632	rogid:v64u66mEVbUV0bRx1LgUftidZDg9606	intact-crc:D80892196D387915|rigid:5uC8H50AdUQRRI+YGoruYtEOUVI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HAP2	uniprotkb:A0A5P8YEG1	intact:EBI-2843709|uniprotkb:O94945|uniprotkb:Q8IXP1|uniprotkb:Q8TAH9|uniprotkb:Q7LC47|uniprotkb:Q8WVQ0|uniprotkb:Q8WYA5|uniprotkb:A7MBN0|ensembl:ENSP00000312834.6|ensembl:ENSP00000486569.2|ensembl:ENSP00000487003.1	intact:EBI-2852022|uniprotkb:Q74UV9|uniprotkb:A0A2U2GXG2|uniprotkb:A0A0H2W3X6|uniprotkb:Q7CHY3|uniprotkb:A0A384KW77	psi-mi:mlxip_human(display_long)|uniprotkb:MLXIP(gene name)|psi-mi:MLXIP(display_short)|uniprotkb:BHLHE36(gene name synonym)|uniprotkb:KIAA0867(gene name synonym)|uniprotkb:MIR(gene name synonym)|uniprotkb:MONDOA(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 36(gene name synonym)|uniprotkb:Transcriptional activator MondoA(gene name synonym)	psi-mi:a0a5p8yeg1_yerpe(display_long)|uniprotkb:flaS(gene name)|psi-mi:flaS(display_short)|uniprotkb:flaW(gene name synonym)|uniprotkb:flgK(gene name synonym)|uniprotkb:YPO1808(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876877|imex:IM-13779-8446	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055753.3|ensembl:ENSG00000175727.15(gene)|ensembl:ENSG00000281178.4(gene)|ensembl:ENST00000319080.12(transcript)|ensembl:ENST00000625732.3(transcript)|ensembl:ENST00000629738.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR052207|panther:PTHR15741(orthology-group)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR002371(Flagellar hook-associated protein)|refseq:WP_002211119.1|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009424""(bacterial-type flagellum hook)|go:""GO:0044780""(bacterial-type flagellum assembly)|interpro:IPR053927|interpro:IPR049119|refseq:YP_002346803.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eJuTx+8vyMJR3oP/Z7hktiDBJ5Y9606	rogid:pNXjB/cj8ecgLe9j2NLbgGL8sgw632	intact-crc:1FCD2423BB301CDA|rigid:fEBWq/CUaiqpnWzRxr8mT8njyPg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZGW9	uniprotkb:O00182	intact:EBI-2856781|uniprotkb:Q0WHP5	intact:EBI-1045193|uniprotkb:O14532|uniprotkb:O75028|uniprotkb:Q9NQ58|uniprotkb:Q3B8N1|intact:EBI-2799360|uniprotkb:A7VJG6|uniprotkb:Q53FQ0|uniprotkb:F8W9W4|uniprotkb:Q8WYQ7|ensembl:ENSP00000378856.2	psi-mi:biod1_yerpe(display_long)|uniprotkb:Dethiobiotin synthase 1(gene name synonym)|uniprotkb:bioD1(gene name)|psi-mi:bioD1(display_short)|uniprotkb:DTB synthetase 1(gene name synonym)|uniprotkb:YPO1154(locus name)|uniprotkb:y3028(locus name)|uniprotkb:YP_1006(locus name)	psi-mi:leg9_human(display_long)|uniprotkb:Tumor antigen HOM-HD-21(gene name synonym)|uniprotkb:Ecalectin(gene name synonym)|uniprotkb:LGALS9(gene name)|psi-mi:LGALS9(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876863|imex:IM-13779-8447	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004472(Dethiobiotin synthase)|interpro:IPR027417|refseq:WP_002216554.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004141""(dethiobiotin synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009102""(biotin biosynthetic process)|refseq:YP_002346193.1|panther:PTHR43210(orthology-group)"	"refseq:NP_002299.2|refseq:NP_033665.1|refseq:XP_006721955.1|refseq:XP_006721958.1|refseq:NP_001317092.1|refseq:XP_016880112.1|ensembl:ENSG00000168961.17(gene)|ensembl:ENST00000395473.7(transcript)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0005534""(galactose binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007565""(female pregnancy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016936""(galactoside binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032834""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043305""(negative regulation of mast cell degranulation)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048030""(disaccharide binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070241""(positive regulation of activated T cell autonomous cell death)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071636""(positive regulation of transforming growth factor beta production)|go:""GO:0071639""(positive regulation of monocyte chemotactic protein-1 production)|go:""GO:0098586""(cellular response to virus)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:2000510""(positive regulation of dendritic cell chemotaxis)|go:""GO:2000562""(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000563""(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000670""(positive regulation of dendritic cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001190""(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001200""(positive regulation of dendritic cell differentiation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:O00182|rcsb pdb:2EAK|rcsb pdb:2EAL|rcsb pdb:2YY1|rcsb pdb:2ZHK|rcsb pdb:2ZHL|rcsb pdb:2ZHM|rcsb pdb:2ZHN|rcsb pdb:3LSD|rcsb pdb:3LSE|rcsb pdb:3NV1|rcsb pdb:3NV2|rcsb pdb:3NV3|rcsb pdb:3NV4|rcsb pdb:3WLU|rcsb pdb:3WV6|reactome:R-HSA-451927|panther:PTHR11346(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qYf9r2/zbn9T1FkMmuqRTeKSAp8632	rogid:v64u66mEVbUV0bRx1LgUftidZDg9606	intact-crc:7BAF66A76FDE0742|rigid:+E7U9SssEel0cLKjAU6JopUGsRE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HAP2	uniprotkb:A0A0H2W2N9	intact:EBI-2843709|uniprotkb:O94945|uniprotkb:Q8IXP1|uniprotkb:Q8TAH9|uniprotkb:Q7LC47|uniprotkb:Q8WVQ0|uniprotkb:Q8WYA5|uniprotkb:A7MBN0|ensembl:ENSP00000312834.6|ensembl:ENSP00000486569.2|ensembl:ENSP00000487003.1	intact:EBI-2840467|uniprotkb:Q74XT4|uniprotkb:Q0WBR4|uniprotkb:A0A384L498|uniprotkb:Q7CKD3|uniprotkb:A0A3N4B9W7	psi-mi:mlxip_human(display_long)|uniprotkb:MLXIP(gene name)|psi-mi:MLXIP(display_short)|uniprotkb:BHLHE36(gene name synonym)|uniprotkb:KIAA0867(gene name synonym)|uniprotkb:MIR(gene name synonym)|uniprotkb:MONDOA(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 36(gene name synonym)|uniprotkb:Transcriptional activator MondoA(gene name synonym)	psi-mi:a0a0h2w2n9_yerpe(display_long)|uniprotkb:degP(gene name)|psi-mi:degP(display_short)|uniprotkb:gsrA(gene name synonym)|uniprotkb:htrA(gene name synonym)|uniprotkb:ptd(gene name synonym)|uniprotkb:YPO3382(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876870|imex:IM-13779-8445	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055753.3|ensembl:ENSG00000175727.15(gene)|ensembl:ENSG00000281178.4(gene)|ensembl:ENST00000319080.12(transcript)|ensembl:ENST00000625732.3(transcript)|ensembl:ENST00000629738.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR052207|panther:PTHR15741(orthology-group)"	"interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:WP_002209370.1|refseq:YP_002348274.1|interpro:IPR036034"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eJuTx+8vyMJR3oP/Z7hktiDBJ5Y9606	rogid:wh5TqHAdstARdvvFDyS2kqzSnxY632	intact-crc:BAC3ECC12209AF49|rigid:PVt3jT6Csbpvjo6GdHI/S34gTAU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00182	uniprotkb:Q7ARD3	intact:EBI-1045193|uniprotkb:O14532|uniprotkb:O75028|uniprotkb:Q9NQ58|uniprotkb:Q3B8N1|intact:EBI-2799360|uniprotkb:A7VJG6|uniprotkb:Q53FQ0|uniprotkb:F8W9W4|uniprotkb:Q8WYQ7|ensembl:ENSP00000378856.2	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:leg9_human(display_long)|uniprotkb:Tumor antigen HOM-HD-21(gene name synonym)|uniprotkb:Ecalectin(gene name synonym)|uniprotkb:LGALS9(gene name)|psi-mi:LGALS9(display_short)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876849|imex:IM-13779-8448	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002299.2|refseq:NP_033665.1|refseq:XP_006721955.1|refseq:XP_006721958.1|refseq:NP_001317092.1|refseq:XP_016880112.1|ensembl:ENSG00000168961.17(gene)|ensembl:ENST00000395473.7(transcript)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0005534""(galactose binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006935""(chemotaxis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007565""(female pregnancy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016936""(galactoside binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032682""(negative regulation of chemokine production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032834""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043305""(negative regulation of mast cell degranulation)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048030""(disaccharide binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060135""(maternal process involved in female pregnancy)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070241""(positive regulation of activated T cell autonomous cell death)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071636""(positive regulation of transforming growth factor beta production)|go:""GO:0071639""(positive regulation of monocyte chemotactic protein-1 production)|go:""GO:0098586""(cellular response to virus)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:2000510""(positive regulation of dendritic cell chemotaxis)|go:""GO:2000562""(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000563""(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:""GO:2000670""(positive regulation of dendritic cell apoptotic process)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001190""(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001200""(positive regulation of dendritic cell differentiation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:O00182|rcsb pdb:2EAK|rcsb pdb:2EAL|rcsb pdb:2YY1|rcsb pdb:2ZHK|rcsb pdb:2ZHL|rcsb pdb:2ZHM|rcsb pdb:2ZHN|rcsb pdb:3LSD|rcsb pdb:3LSE|rcsb pdb:3NV1|rcsb pdb:3NV2|rcsb pdb:3NV3|rcsb pdb:3NV4|rcsb pdb:3WLU|rcsb pdb:3WV6|reactome:R-HSA-451927|panther:PTHR11346(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v64u66mEVbUV0bRx1LgUftidZDg9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:13392C55B2852C6A|rigid:T2AJLzATrGw9BYFNdijMHRydYhI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W8Z8	uniprotkb:A6NM11	intact:EBI-2856746|uniprotkb:Q74QD6|uniprotkb:A0A3N4B8Z3|uniprotkb:Q7CGV9|uniprotkb:Q0WII5	intact:EBI-2839192|uniprotkb:B7ZMC3|ensembl:ENSP00000459551.1	psi-mi:a0a0h2w8z8_yerpe(display_long)|uniprotkb:bgaB(gene name)|psi-mi:bgaB(display_short)|uniprotkb:pbg(gene name synonym)|uniprotkb:YPO0852(locus name)	psi-mi:l37a2_human(display_long)|uniprotkb:LRRC37A2(gene name)|psi-mi:LRRC37A2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876891|imex:IM-13779-8451	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029062|interpro:IPR013739(Beta-galactosidase C-terminal)|interpro:IPR013738(Beta-galactosidase trimerisation)|interpro:IPR003476(Glycoside hydrolase, family 42)|interpro:IPR013529(Glycoside hydrolase, family 42, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209897.1|go:""GO:0004565""(beta-galactosidase activity)|go:""GO:0006012""(galactose metabolic process)|go:""GO:0009341""(beta-galactosidase complex)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:YP_002345903.1"	"refseq:NP_001006608.2|ensembl:ENSG00000238083.10(gene)|ensembl:ENST00000576629.6(transcript)|go:""GO:0016020""(membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR015753(Proline-rich Peptides)|interpro:IPR029423|interpro:IPR032675|interpro:IPR032754|panther:PTHR23045(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FQsKPHA93Zu/VST9+vZv6zeQ8DA632	rogid:gxbDK5S8RBURcHHakXM/ohMyIP49606	intact-crc:CB705C2FC0F47C47|rigid:vkFsPEoUgwJdi3WXYKQAOS9O49Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PM91	uniprotkb:A6NM11	intact:EBI-2845565|uniprotkb:Q74XN3|uniprotkb:Q7CKA1|uniprotkb:A0A0H2W0J0|uniprotkb:Q0WBX7	intact:EBI-2839192|uniprotkb:B7ZMC3|ensembl:ENSP00000459551.1	psi-mi:a0a2s9pm91_yerpe(display_long)|uniprotkb:rbsC(gene name)|psi-mi:rbsC(display_short)|uniprotkb:YPO3315(locus name)	psi-mi:l37a2_human(display_long)|uniprotkb:LRRC37A2(gene name)|psi-mi:LRRC37A2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876884|imex:IM-13779-8449	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|refseq:WP_002209437.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:YP_002348211.1"	"refseq:NP_001006608.2|ensembl:ENSG00000238083.10(gene)|ensembl:ENST00000576629.6(transcript)|go:""GO:0016020""(membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR015753(Proline-rich Peptides)|interpro:IPR029423|interpro:IPR032675|interpro:IPR032754|panther:PTHR23045(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QdtHo9H/Vuz7QOXdAkSbm2MTatU632	rogid:gxbDK5S8RBURcHHakXM/ohMyIP49606	intact-crc:6C036AD8F22F4CFD|rigid:9BmMalACZ8VtoQvSaqYXmdtSREM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A6NM11	uniprotkb:A0A2S9PFM0	intact:EBI-2839192|uniprotkb:B7ZMC3|ensembl:ENSP00000459551.1	intact:EBI-2846871|uniprotkb:Q74QH1|uniprotkb:A0A0H2W7H4|uniprotkb:Q7CGR9|uniprotkb:A0A384LFS9	psi-mi:l37a2_human(display_long)|uniprotkb:LRRC37A2(gene name)|psi-mi:LRRC37A2(display_short)	psi-mi:a0a2s9pfm0_yerpe(display_long)|uniprotkb:YPO0938(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876898|imex:IM-13779-8452	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001006608.2|ensembl:ENSG00000238083.10(gene)|ensembl:ENST00000576629.6(transcript)|go:""GO:0016020""(membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR015753(Proline-rich Peptides)|interpro:IPR029423|interpro:IPR032675|interpro:IPR032754|panther:PTHR23045(orthology-group)"	"interpro:IPR017755(N-carbamoylputrescine amidase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:WP_002209979.1|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0050126""(N-carbamoylputrescine amidase activity)|interpro:IPR036526|refseq:YP_002345985.1|interpro:IPR050345"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gxbDK5S8RBURcHHakXM/ohMyIP49606	rogid:VEt5ZICBEzJqD2dQaZCgWKgplSI632	intact-crc:C29C61E040F52417|rigid:kR4IWObfVFfg4M05hILsiiTSMqI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCW0	uniprotkb:Q9UHN6	intact:EBI-2842923|uniprotkb:Q7CJK9|uniprotkb:Q0WD52|uniprotkb:Q74SA7	intact:EBI-2876905|uniprotkb:B2RTQ6|uniprotkb:Q8NBP6|uniprotkb:Q5T841|uniprotkb:Q5T840|uniprotkb:Q9P2D5|uniprotkb:Q5T839|uniprotkb:Q5T838|uniprotkb:A6H8W9|ensembl:ENSP00000366243.4	psi-mi:mdtb_yerpe(display_long)|uniprotkb:mdtB(gene name)|psi-mi:mdtB(display_short)|uniprotkb:Multidrug transporter MdtB(gene name synonym)|uniprotkb:YPO2848(locus name)|uniprotkb:y1385(locus name)|uniprotkb:YP_2715(locus name)	psi-mi:ceip2_human(display_long)|uniprotkb:CEMIP2(gene name)|psi-mi:CEMIP2(display_short)|uniprotkb:KIAA1412(gene name synonym)|uniprotkb:TMEM2(gene name synonym)|uniprotkb:Transmembrane protein 2(gene name synonym)|uniprotkb:Cell migration-inducing hyaluronidase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876917|imex:IM-13779-8450	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR022831|interpro:IPR027463|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:WP_002209793.1|refseq:YP_002347786.1|panther:PTHR32063(orthology-group)"	"refseq:NP_001129292.1|refseq:NP_037522.1|ensembl:ENSG00000135048.14(gene)|ensembl:ENST00000377044.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903670""(regulation of sprouting angiogenesis)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR019316|interpro:IPR039473|interpro:IPR039477|interpro:IPR052252|mint:Q9UHN6|rcsb pdb:8C6I|refseq:XP_005251926.1|panther:PTHR15535(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LHw1WKWrAW5/xlsQ5C6WVb5Ua3M632	rogid:LVdpEH7Df1biSXHseli56Y9l9XQ9606	intact-crc:2C883289123B2659|rigid:L/SI3tcjUAT7uIKJao8NCY6X3sw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A4QPH0	uniprotkb:Q8D1D2	intact:EBI-2876938	intact:EBI-2849752|uniprotkb:Q74X70	psi-mi:a4qph0_human(display_long)|uniprotkb:SLC5A1(gene name)|psi-mi:SLC5A1(display_short)|uniprotkb:High affinity sodium-glucose cotransporter(gene name synonym)|uniprotkb:Solute carrier family 5 member 1(gene name synonym)	psi-mi:q8d1d2_yerpe(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:y0687(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876935|imex:IM-13779-8455	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0015370""(""solute:sodium symporter activity"")|go:""GO:0016324""(apical plasma membrane)|interpro:IPR001734(Na+/solute symporter)|interpro:IPR018212|interpro:IPR038377"	"interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010214(Transcription termination factor NusA, C-terminal duplication)|interpro:IPR010213(Transcription termination factor NusA)|interpro:IPR025249|interpro:IPR030842|go:""GO:0000166""(nucleotide binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|interpro:IPR036555"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wgFKNQv3j9p2XrTLjPgIMBH+rOU9606	rogid:YzZfDXwWbJbXKFeHL1SADDhW96Q632	intact-crc:70CB6BB49142D24E|rigid:4z1up6MIR3HbBsVOuM/jC8yTSo0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0V0	uniprotkb:Q9Y2L8	intact:EBI-2849272	intact:EBI-2876965|intact:EBI-28975936|ensembl:ENSP00000322872.5|ensembl:ENSP00000377725.2|ensembl:ENSP00000392104.1|uniprotkb:A4D280|uniprotkb:D6W5S9	psi-mi:q8d0v0_yerpe(display_long)|uniprotkb:fadL(gene name)|psi-mi:fadL(display_short)|uniprotkb:Outer membrane FadL protein(gene name synonym)|uniprotkb:Outer membrane flp protein(gene name synonym)|uniprotkb:y1577(locus name)	psi-mi:zksc5_human(display_long)|uniprotkb:ZKSCAN5(gene name)|psi-mi:ZKSCAN5(display_short)|uniprotkb:KIAA1015(gene name synonym)|uniprotkb:ZFP95(gene name synonym)|uniprotkb:Zinc finger protein 95 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876970|imex:IM-13779-8454	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005017(Membrane protein involved in aromatic hydrocarbon degradation)|go:""GO:0006869""(lipid transport)|go:""GO:0009279""(cell outer membrane)"	"ensembl:ENSG00000196652.12(gene)|ensembl:ENST00000326775.10(transcript)|ensembl:ENST00000394170.6(transcript)|ensembl:ENST00000451158.5(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q9Y2L8|rcsb pdb:2EM5|rcsb pdb:2EMM|rcsb pdb:2EMZ|rcsb pdb:2EN3|rcsb pdb:2EOM|rcsb pdb:2EON|rcsb pdb:2EOO|rcsb pdb:2YSO|rcsb pdb:2YTG|reactome:R-HSA-212436|refseq:NP_001305011.1|refseq:NP_001305012.1|refseq:NP_001305013.1|refseq:NP_055384.1|refseq:NP_659570.1|refseq:XP_016867407.1|refseq:XP_016867408.1|panther:PTHR24377(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t3ttYDBykbAjdOq/JpJE2QGeyvk632	rogid:IGLnMrywMbMAwqoSnoXhPKm3Hus9606	intact-crc:833FA20518DACCA6|rigid:p1vRIgxaddEgrWSP8xS2KreYKgk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H112	uniprotkb:P43657	intact:EBI-2855255|uniprotkb:Q0WFG7|uniprotkb:A0A5P8YF71|uniprotkb:Q7CI82|uniprotkb:A0A384LKP6	intact:EBI-2876949|ensembl:ENSP00000344353.2|ensembl:ENSP00000367691.3|ensembl:ENSP00000482660.1|uniprotkb:Q53FA0|uniprotkb:Q7Z3S0|uniprotkb:Q3KPF5|uniprotkb:Q5VW44|uniprotkb:O15133|uniprotkb:Q7Z3S6|uniprotkb:B3KVF2|uniprotkb:F2YGU4|uniprotkb:A4FTW9	psi-mi:a0a2u2h112_yerpe(display_long)|uniprotkb:YPO1986(locus name)	psi-mi:lpar6_human(display_long)|uniprotkb:LPAR6(gene name)|psi-mi:LPAR6(display_short)|uniprotkb:P2RY5(gene name synonym)|uniprotkb:Oleoyl-L-alpha-lysophosphatidic acid receptor(gene name synonym)|uniprotkb:P2Y purinoceptor 5(gene name synonym)|uniprotkb:Purinergic receptor 5(gene name synonym)|uniprotkb:RB intron encoded G-protein coupled receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876946|imex:IM-13779-8456	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002211268.1|refseq:YP_002346971.1	"ensembl:ENST00000345941.2(transcript)|ensembl:ENSG00000139679.16(gene)|ensembl:ENST00000378434.8(transcript)|ensembl:ENST00000620633.5(transcript)|go:""GO:0001835""(blastocyst hatching)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0070915""(lysophosphatidic acid receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P43657|reactome:R-HSA-416476|reactome:R-HSA-417957|refseq:NP_001155969.1|refseq:NP_001155970.1|refseq:NP_005758.2|efo:""Orphanet:170""|efo:""Orphanet:55654""|panther:PTHR24232(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/24Nff8tFbMXOOsf1M0FFW0gsN8632	rogid:P+X2vlEYWomdIDveBaFHGf5r2389606	intact-crc:927616F37DDD2FD4|rigid:F2nc6G02Nn3B7ly8eLWLB+DIPBQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PDY1	uniprotkb:Q9ULC5	intact:EBI-2848416|uniprotkb:Q74UI0|uniprotkb:A0A0H2W558|uniprotkb:Q7CIW0|uniprotkb:A0A384L8E0	intact:EBI-2876927|ensembl:ENSP00000346680.4|ensembl:ENSP00000376796.1|intact:EBI-4279951|uniprotkb:A6GV77|uniprotkb:D3DRB3|uniprotkb:Q6UX44|uniprotkb:Q9UIU4	psi-mi:a0a380pdy1_yerpe(display_long)|uniprotkb:ogl(gene name)|psi-mi:ogl(display_short)|uniprotkb:YPO1713(locus name)	psi-mi:acsl5_human(display_long)|uniprotkb:ACSL5(gene name)|psi-mi:ACSL5(display_short)|uniprotkb:ACS5(gene name synonym)|uniprotkb:FACL5(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 5(gene name synonym)|uniprotkb:UNQ633/PRO1250(orf name)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876924|imex:IM-13779-8453	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027946|refseq:WP_002210841.1|go:""GO:0045490""(pectin catabolic process)|go:""GO:0047487""(oligogalacturonide lyase activity)|refseq:YP_002346716.1|panther:PTHR36842(orthology-group)"	"ensembl:ENSG00000197142.11(gene)|ensembl:ENST00000354655.9(transcript)|ensembl:ENST00000393081.6(transcript)|go:""GO:0001676""(long-chain fatty acid metabolic process)|go:""GO:0004467""(long-chain fatty acid-CoA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0010747""(positive regulation of long-chain fatty acid import across plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0035338""(long-chain fatty-acyl-CoA biosynthetic process)|go:""GO:0047676""(arachidonate-CoA ligase activity)|go:""GO:0090434""(oleoyl-CoA ligase activity)|go:""GO:2001236""(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR042099|interpro:IPR045311|mint:Q9ULC5|reactome:R-HSA-75876|refseq:NP_057318.2|refseq:NP_976313.1|refseq:NP_976314.1|panther:PTHR43272(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:e8mn+xTHxqbWMCnpEvzfGUD7MYI632	rogid:7l7cPhRg+nK3L/cT30/CpJe+s0g9606	intact-crc:963BC41B61066ED1|rigid:uHn+a8Y0lMeLQbx0JZxXvGCJTB0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q65AP2	uniprotkb:P01023	intact:EBI-2868875|uniprotkb:Q74YN9|uniprotkb:Q9ZH06|uniprotkb:A0A384K9S5|uniprotkb:A0A1U8QKQ0|uniprotkb:Q7ARA5|uniprotkb:A0A2U2H128	intact:EBI-640741|uniprotkb:Q13677|uniprotkb:Q59F47|uniprotkb:Q5QTS0|uniprotkb:Q68DN2|uniprotkb:Q6PIY3|uniprotkb:Q6PN97|ensembl:ENSP00000323929.8	psi-mi:q65ap2_yerpe(display_long)|uniprotkb:YPMT1.26Ac(gene name)|psi-mi:YPMT1.26Ac(display_short)	psi-mi:a2mg_human(display_long)|uniprotkb:CPAMD5(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5(gene name synonym)|uniprotkb:A2M(gene name)|psi-mi:A2M(display_short)|uniprotkb:FWP007(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877018|imex:IM-13779-8461	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395364.1|refseq:YP_093905.1|refseq:WP_002211790.1	"refseq:NP_000005.2|refseq:NP_001334352.1|refseq:NP_001334353.1|refseq:NP_001334354.1|ensembl:ENSG00000175899.15(gene)|ensembl:ENST00000318602.12(transcript)|go:""GO:0001553""(luteinization)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|go:""GO:0001869""(negative regulation of complement activation, lectin pathway)|go:""GO:0002020""(protease binding)|go:""GO:0002438""(acute inflammatory response to antigenic stimulus)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0010037""(response to carbon dioxide)|go:""GO:0019838""(growth factor binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0019959""(interleukin-8 binding)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0042802""(identical protein binding)|go:""GO:0043120""(tumor necrosis factor binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048403""(brain-derived neurotrophic factor binding)|go:""GO:0048406""(nerve growth factor binding)|go:""GO:0048863""(stem cell differentiation)|interpro:IPR010916(TonB box, conserved site)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990402""(embryonic liver development)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|interpro:IPR047565|interpro:IPR050473|mint:P01023|rcsb pdb:1BV8|rcsb pdb:2P9R|rcsb pdb:6TAV|rcsb pdb:7O7L|rcsb pdb:7O7M|rcsb pdb:7O7N|rcsb pdb:7O7O|rcsb pdb:7O7P|rcsb pdb:7O7Q|rcsb pdb:7O7R|rcsb pdb:7O7S|rcsb pdb:7VON|rcsb pdb:7VOO|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-1474228|reactome:R-HSA-8963896|dip:DIP-1118N|panther:PTHR11412(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/15	rogid:7bbIpe6HMjF07dDnpqVj+x0E36I632	rogid:FClLRDrtOWUx0eBBCUfAocx0Q+49606	intact-crc:D93F5367C50463F5|rigid:y0ogrNzXMdH66FOaxio+5lLDRIo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2L8	uniprotkb:A0A2U2H0W0	intact:EBI-2876965|intact:EBI-28975936|ensembl:ENSP00000322872.5|ensembl:ENSP00000377725.2|ensembl:ENSP00000392104.1|uniprotkb:A4D280|uniprotkb:D6W5S9	intact:EBI-2857561|uniprotkb:Q74U91|uniprotkb:Q0WFF6|uniprotkb:A0A380PDB4|uniprotkb:Q7CI92|uniprotkb:A0A384L848	psi-mi:zksc5_human(display_long)|uniprotkb:ZKSCAN5(gene name)|psi-mi:ZKSCAN5(display_short)|uniprotkb:KIAA1015(gene name synonym)|uniprotkb:ZFP95(gene name synonym)|uniprotkb:Zinc finger protein 95 homolog(gene name synonym)	psi-mi:a0a2u2h0w0_yerpe(display_long)|uniprotkb:YPO1997(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876977|imex:IM-13779-8457	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000196652.12(gene)|ensembl:ENST00000326775.10(transcript)|ensembl:ENST00000394170.6(transcript)|ensembl:ENST00000451158.5(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q9Y2L8|rcsb pdb:2EM5|rcsb pdb:2EMM|rcsb pdb:2EMZ|rcsb pdb:2EN3|rcsb pdb:2EOM|rcsb pdb:2EON|rcsb pdb:2EOO|rcsb pdb:2YSO|rcsb pdb:2YTG|reactome:R-HSA-212436|refseq:NP_001305011.1|refseq:NP_001305012.1|refseq:NP_001305013.1|refseq:NP_055384.1|refseq:NP_659570.1|refseq:XP_016867407.1|refseq:XP_016867408.1|panther:PTHR24377(orthology-group)"	interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR052750|interpro:IPR029058|refseq:WP_002211257.1|refseq:YP_002346982.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IGLnMrywMbMAwqoSnoXhPKm3Hus9606	rogid:DP6LxF8YTJKUt3yW/2M2CRKvosU632	intact-crc:A766C13E933C62F5|rigid:wy3Vb4vTPJKZ1ERMURqEZZHv6u0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A4D0T8	uniprotkb:P17778	intact:EBI-2877003	intact:EBI-2842665|uniprotkb:O68701	psi-mi:a4d0t8_human(display_long)|uniprotkb:GPR85(gene name)|psi-mi:GPR85(display_short)|uniprotkb:hCG_1648128(orf name)|uniprotkb:tcag7.60(orf name)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877000|imex:IM-13779-8458	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|refseq:NP_001139737.1|refseq:NP_001139738.1|refseq:NP_001139739.1|refseq:NP_061843.3|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|refseq:XP_005250508.1|refseq:XP_016867841.1|interpro:IPR051509"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1Mwj4HCUBy2mozRFvnnEOCYPW8w9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:CB9D5B17550D7020|rigid:8RnxETu9m9spJdF6SEwlx5EkJYQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZMT4	uniprotkb:A0A2S9PJE2	intact:EBI-2876984|ensembl:ENSP00000380692.2|uniprotkb:Q6MZL8|uniprotkb:C9JQU2|uniprotkb:C9JJH9|uniprotkb:Q9C0E5|uniprotkb:A4D1S9	intact:EBI-2850829|uniprotkb:Q74WU5|uniprotkb:Q0WC89|uniprotkb:Q7CK47|uniprotkb:A0A384L2F1	psi-mi:kdm7a_human(display_long)|uniprotkb:KDM7A(gene name)|psi-mi:KDM7A(display_short)|uniprotkb:JHDM1D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1D(gene name synonym)|uniprotkb:KDM7(gene name synonym)|uniprotkb:KIAA1718(gene name synonym)|uniprotkb:Lysine-specific demethylase 7(gene name synonym)|uniprotkb:[histone H3]-dimethyl-L-lysine9 demethylase 7A(gene name synonym)	psi-mi:a0a2s9pje2_yerpe(display_long)|uniprotkb:ahpC(gene name)|psi-mi:ahpC(display_short)|uniprotkb:YPO3194(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2876993|imex:IM-13779-8460	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000006459.11(gene)|ensembl:ENST00000397560.7(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016706""(2-oxoglutarate-dependent dioxygenase activity)|go:""GO:0030901""(midbrain development)|go:""GO:0032452""(histone demethylase activity)|go:""GO:0032454""(histone H3K9 demethylase activity)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035575""(histone H4K20 demethylase activity)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051864""(histone H3K36 demethylase activity)|go:""GO:0071558""(histone H3K27me2/H3K27me3 demethylase activity)|go:""GO:0140683""(histone H3K9me/H3K9me2 demethylase activity)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR041070|interpro:IPR050690|mint:Q6ZMT4|rcsb pdb:3KV5|rcsb pdb:3KV6|rcsb pdb:3KV9|rcsb pdb:3KVA|rcsb pdb:3KVB|rcsb pdb:3U78|reactome:R-HSA-3214842|reactome:R-HSA-6802952|refseq:NP_085150.1|panther:PTHR23123(orthology-group)"	"interpro:IPR013766(Thioredoxin domain)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|refseq:WP_002208675.1|go:""GO:0005829""(cytosol)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0045454""(cell redox homeostasis)|interpro:IPR036249|refseq:YP_002348099.1|interpro:IPR050217|panther:PTHR10681(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4hG667PsNHVo/iN1r+prkmVYBhQ9606	rogid:GnZEc/ZzTTpq4nrPnH46z4CNIwg632	intact-crc:D24FC28197EEF174|rigid:S7RD+PYb3hFCJ4NeEfY0S0X4o8s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17778	uniprotkb:P01023	intact:EBI-2842665|uniprotkb:O68701	intact:EBI-640741|uniprotkb:Q13677|uniprotkb:Q59F47|uniprotkb:Q5QTS0|uniprotkb:Q68DN2|uniprotkb:Q6PIY3|uniprotkb:Q6PN97|ensembl:ENSP00000323929.8	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	psi-mi:a2mg_human(display_long)|uniprotkb:CPAMD5(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5(gene name synonym)|uniprotkb:A2M(gene name)|psi-mi:A2M(display_short)|uniprotkb:FWP007(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877011|imex:IM-13779-8459	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"refseq:NP_000005.2|refseq:NP_001334352.1|refseq:NP_001334353.1|refseq:NP_001334354.1|ensembl:ENSG00000175899.15(gene)|ensembl:ENST00000318602.12(transcript)|go:""GO:0001553""(luteinization)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|go:""GO:0001869""(negative regulation of complement activation, lectin pathway)|go:""GO:0002020""(protease binding)|go:""GO:0002438""(acute inflammatory response to antigenic stimulus)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0010037""(response to carbon dioxide)|go:""GO:0019838""(growth factor binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0019959""(interleukin-8 binding)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0042802""(identical protein binding)|go:""GO:0043120""(tumor necrosis factor binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048403""(brain-derived neurotrophic factor binding)|go:""GO:0048406""(nerve growth factor binding)|go:""GO:0048863""(stem cell differentiation)|interpro:IPR010916(TonB box, conserved site)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990402""(embryonic liver development)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|interpro:IPR047565|interpro:IPR050473|mint:P01023|rcsb pdb:1BV8|rcsb pdb:2P9R|rcsb pdb:6TAV|rcsb pdb:7O7L|rcsb pdb:7O7M|rcsb pdb:7O7N|rcsb pdb:7O7O|rcsb pdb:7O7P|rcsb pdb:7O7Q|rcsb pdb:7O7R|rcsb pdb:7O7S|rcsb pdb:7VON|rcsb pdb:7VOO|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-1474228|reactome:R-HSA-8963896|dip:DIP-1118N|panther:PTHR11412(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/15	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	rogid:FClLRDrtOWUx0eBBCUfAocx0Q+49606	intact-crc:6DBBD1474D3DDCD4|rigid:c0LOwoPFyiD/C268/fLw+aUmUzY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99550	uniprotkb:Q8ZGJ1	intact:EBI-2511359|ensembl:ENSP00000475489.1|intact:EBI-2809473|uniprotkb:U3KQ28|uniprotkb:Q9H976|uniprotkb:A6NEE2|uniprotkb:A1L486|uniprotkb:B3KR87|uniprotkb:A0A0A0MTP3	intact:EBI-2877056|uniprotkb:Q0WHA7	psi-mi:mpp9_human(display_long)|uniprotkb:MPHOSPH9(gene name)|psi-mi:MPHOSPH9(display_short)|uniprotkb:MPP9(gene name synonym)	psi-mi:end4_yerpe(display_long)|uniprotkb:nfo(gene name)|psi-mi:nfo(display_short)|uniprotkb:Endodeoxyribonuclease IV(gene name synonym)|uniprotkb:Endonuclease IV(gene name synonym)|uniprotkb:YPO1306(locus name)|uniprotkb:y2879(locus name)|uniprotkb:YP_1286(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877061|imex:IM-13779-8462	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000051825.15(gene)|ensembl:ENST00000606320.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0016020""(membrane)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR026636|mint:Q99550|refseq:NP_073619.3|refseq:XP_016874162.1|refseq:XP_016874168.1|refseq:XP_016874169.1|panther:PTHR14926(orthology-group)"	"go:""GO:0003677""(DNA binding)|go:""GO:0003906""(""DNA-(apurinic or apyrimidinic site) endonuclease activity"")|go:""GO:0006284""(base-excision repair)|go:""GO:0008081""(phosphoric diester hydrolase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008833""(""deoxyribonuclease IV (phage-T4-induced) activity"")|refseq:YP_002346331.1|interpro:IPR018246|interpro:IPR001719(AP endonuclease, family 2)|interpro:IPR013022(Xylose isomerase-like, TIM barrel)|refseq:WP_002208791.1|interpro:IPR036237|panther:PTHR21445(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:J1FkA3DERPWTHe57z9hMj6V52xI9606	rogid:RpaePlt2i6vSSFW7fbZx4UMAZkk632	intact-crc:A2B4CD3801A6FF9B|rigid:397tZ6Y77IeSnxHPH4+l7WvrMeU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0W9W3	uniprotkb:P01023	intact:EBI-2850864|uniprotkb:Q74PD6|uniprotkb:A0A0H2W8D7|uniprotkb:A0A380PJZ2|uniprotkb:Q7CFP7|uniprotkb:A0A384K9N9	intact:EBI-640741|uniprotkb:Q13677|uniprotkb:Q59F47|uniprotkb:Q5QTS0|uniprotkb:Q68DN2|uniprotkb:Q6PIY3|uniprotkb:Q6PN97|ensembl:ENSP00000323929.8	psi-mi:q0w9w3_yerpe(display_long)|uniprotkb:mtlA(gene name)|psi-mi:mtlA(display_short)|uniprotkb:EIICBA-Mtl(gene name synonym)|uniprotkb:YPO4068(locus name)	psi-mi:a2mg_human(display_long)|uniprotkb:CPAMD5(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5(gene name synonym)|uniprotkb:A2M(gene name)|psi-mi:A2M(display_short)|uniprotkb:FWP007(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877049|imex:IM-13779-8463	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013011(Phosphotransferase system, EIIB component, type 2)|interpro:IPR013014(Phosphotransferase system, EIIC component, type 2)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|interpro:IPR003501(Phosphotransferase system, lactose/cellobiose-specific IIB subunit)|interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR004718(Phosphotransferase system, mannitol-specific enzyme IIC)|interpro:IPR029503|refseq:WP_002209621.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0022872""(""protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity"")|interpro:IPR036095|refseq:YP_002348925.1|interpro:IPR050893"	"refseq:NP_000005.2|refseq:NP_001334352.1|refseq:NP_001334353.1|refseq:NP_001334354.1|ensembl:ENSG00000175899.15(gene)|ensembl:ENST00000318602.12(transcript)|go:""GO:0001553""(luteinization)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|go:""GO:0001869""(negative regulation of complement activation, lectin pathway)|go:""GO:0002020""(protease binding)|go:""GO:0002438""(acute inflammatory response to antigenic stimulus)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0010037""(response to carbon dioxide)|go:""GO:0019838""(growth factor binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0019959""(interleukin-8 binding)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0042802""(identical protein binding)|go:""GO:0043120""(tumor necrosis factor binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048403""(brain-derived neurotrophic factor binding)|go:""GO:0048406""(nerve growth factor binding)|go:""GO:0048863""(stem cell differentiation)|interpro:IPR010916(TonB box, conserved site)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990402""(embryonic liver development)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|interpro:IPR047565|interpro:IPR050473|mint:P01023|rcsb pdb:1BV8|rcsb pdb:2P9R|rcsb pdb:6TAV|rcsb pdb:7O7L|rcsb pdb:7O7M|rcsb pdb:7O7N|rcsb pdb:7O7O|rcsb pdb:7O7P|rcsb pdb:7O7Q|rcsb pdb:7O7R|rcsb pdb:7O7S|rcsb pdb:7VON|rcsb pdb:7VOO|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-1474228|reactome:R-HSA-8963896|dip:DIP-1118N|panther:PTHR11412(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/15	rogid:IRMdiu3ZdRcaOFT1CtHmg2fPok8632	rogid:FClLRDrtOWUx0eBBCUfAocx0Q+49606	intact-crc:BA948F0AE3591A70|rigid:3B2cR/d+GwBLrk/ylIPHhV429Rw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01023	uniprotkb:A0A0H2W3N2	intact:EBI-640741|uniprotkb:Q13677|uniprotkb:Q59F47|uniprotkb:Q5QTS0|uniprotkb:Q68DN2|uniprotkb:Q6PIY3|uniprotkb:Q6PN97|ensembl:ENSP00000323929.8	intact:EBI-2877037|uniprotkb:Q74V91|uniprotkb:Q0WGN2|uniprotkb:Q7CHS1|uniprotkb:A0A3N4B4D0|uniprotkb:A0A384KEN5	psi-mi:a2mg_human(display_long)|uniprotkb:CPAMD5(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5(gene name synonym)|uniprotkb:A2M(gene name)|psi-mi:A2M(display_short)|uniprotkb:FWP007(orf name)	psi-mi:a0a0h2w3n2_yerpe(display_long)|uniprotkb:galF(gene name)|psi-mi:galF(display_short)|uniprotkb:UDP-glucose pyrophosphorylase(gene name synonym)|uniprotkb:YPO1540(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877042|imex:IM-13779-8465	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000005.2|refseq:NP_001334352.1|refseq:NP_001334353.1|refseq:NP_001334354.1|ensembl:ENSG00000175899.15(gene)|ensembl:ENST00000318602.12(transcript)|go:""GO:0001553""(luteinization)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|go:""GO:0001869""(negative regulation of complement activation, lectin pathway)|go:""GO:0002020""(protease binding)|go:""GO:0002438""(acute inflammatory response to antigenic stimulus)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0010037""(response to carbon dioxide)|go:""GO:0019838""(growth factor binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0019959""(interleukin-8 binding)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0042802""(identical protein binding)|go:""GO:0043120""(tumor necrosis factor binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048403""(brain-derived neurotrophic factor binding)|go:""GO:0048406""(nerve growth factor binding)|go:""GO:0048863""(stem cell differentiation)|interpro:IPR010916(TonB box, conserved site)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990402""(embryonic liver development)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|interpro:IPR047565|interpro:IPR050473|mint:P01023|rcsb pdb:1BV8|rcsb pdb:2P9R|rcsb pdb:6TAV|rcsb pdb:7O7L|rcsb pdb:7O7M|rcsb pdb:7O7N|rcsb pdb:7O7O|rcsb pdb:7O7P|rcsb pdb:7O7Q|rcsb pdb:7O7R|rcsb pdb:7O7S|rcsb pdb:7VON|rcsb pdb:7VOO|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-1474228|reactome:R-HSA-8963896|dip:DIP-1118N|panther:PTHR11412(orthology-group)"	"go:""GO:0003983""(""UTP:glucose-1-phosphate uridylyltransferase activity"")|go:""GO:0006011""(UDP-alpha-D-glucose metabolic process)|go:""GO:0009058""(biosynthetic process)|interpro:IPR029044|interpro:IPR005771(UTP--glucose-1-phosphate uridylyltransferase, bacterial and archaeal type)|interpro:IPR005835(Nucleotidyl transferase)|refseq:YP_002346556.1|refseq:WP_002211887.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/15	rogid:FClLRDrtOWUx0eBBCUfAocx0Q+49606	rogid:Np5YxBMOQkxjDYaqem36NDMdpV8632	intact-crc:9070FCD770EF2696|rigid:m0m7DM0SpDC32lLhWutInAjGy4I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01023	uniprotkb:Q8CZJ2	intact:EBI-640741|uniprotkb:Q13677|uniprotkb:Q59F47|uniprotkb:Q5QTS0|uniprotkb:Q68DN2|uniprotkb:Q6PIY3|uniprotkb:Q6PN97|ensembl:ENSP00000323929.8	intact:EBI-2877025|uniprotkb:Q74Y09	psi-mi:a2mg_human(display_long)|uniprotkb:CPAMD5(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5(gene name synonym)|uniprotkb:A2M(gene name)|psi-mi:A2M(display_short)|uniprotkb:FWP007(orf name)	psi-mi:q8czj2_yerpe(display_long)|uniprotkb:prkB(gene name)|psi-mi:prkB(display_short)|uniprotkb:prk(gene name synonym)|uniprotkb:YP_0177(locus name)|uniprotkb:y3959(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877030|imex:IM-13779-8464	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000005.2|refseq:NP_001334352.1|refseq:NP_001334353.1|refseq:NP_001334354.1|ensembl:ENSG00000175899.15(gene)|ensembl:ENST00000318602.12(transcript)|go:""GO:0001553""(luteinization)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|go:""GO:0001869""(negative regulation of complement activation, lectin pathway)|go:""GO:0002020""(protease binding)|go:""GO:0002438""(acute inflammatory response to antigenic stimulus)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006953""(acute-phase response)|go:""GO:0007584""(response to nutrient)|go:""GO:0010037""(response to carbon dioxide)|go:""GO:0019838""(growth factor binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0019959""(interleukin-8 binding)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0042802""(identical protein binding)|go:""GO:0043120""(tumor necrosis factor binding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048403""(brain-derived neurotrophic factor binding)|go:""GO:0048406""(nerve growth factor binding)|go:""GO:0048863""(stem cell differentiation)|interpro:IPR010916(TonB box, conserved site)|go:""GO:0051384""(response to glucocorticoid)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:1990402""(embryonic liver development)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|interpro:IPR047565|interpro:IPR050473|mint:P01023|rcsb pdb:1BV8|rcsb pdb:2P9R|rcsb pdb:6TAV|rcsb pdb:7O7L|rcsb pdb:7O7M|rcsb pdb:7O7N|rcsb pdb:7O7O|rcsb pdb:7O7P|rcsb pdb:7O7Q|rcsb pdb:7O7R|rcsb pdb:7O7S|rcsb pdb:7VON|rcsb pdb:7VOO|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-1474228|reactome:R-HSA-8963896|dip:DIP-1118N|panther:PTHR11412(orthology-group)"	"go:""GO:0005524""(ATP binding)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008974""(phosphoribulokinase activity)|interpro:IPR006082(Phosphoribulokinase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/15	rogid:FClLRDrtOWUx0eBBCUfAocx0Q+49606	rogid:pZ4eRZrpzhw+v7SVtrQpiRzFTWo632	intact-crc:142A78356B03F5D9|rigid:s1bWHTKLl2SvfYlrvtQ0rQxGeOc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IZ83	uniprotkb:Q8CZS2	intact:EBI-1044483|uniprotkb:C9JBH6|uniprotkb:Q86YF0|uniprotkb:Q8IYL4|uniprotkb:Q8TEI8|uniprotkb:B4DLQ1|ensembl:ENSP00000293350.3	intact:EBI-2845681	psi-mi:a16a1_human(display_long)|uniprotkb:ALDH16A1(gene name)|psi-mi:ALDH16A1(display_short)	psi-mi:q8czs2_yerpe(display_long)|uniprotkb:icc(gene name)|psi-mi:icc(display_short)|uniprotkb:y3513(locus name)|uniprotkb:cpdA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877082|imex:IM-13779-8468	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_699160.2|refseq:NP_001138868.1|ensembl:ENSG00000161618.10(gene)|ensembl:ENST00000293350.9(transcript)|go:""GO:0016020""(membrane)|go:""GO:0016620""(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q8IZ83|panther:PTHR11699(orthology-group)"	"interpro:IPR026575|interpro:IPR046379|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|go:""GO:0000166""(nucleotide binding)|go:""GO:0004115""(3',5'-cyclic-AMP phosphodiesterase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR050884"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BoCNAGkgDh2oJaclyaoXr117+iw9606	rogid:pHtA80uk66ZaIBbjEM2kYqV0pog632	intact-crc:6FED29371073DB3E|rigid:8TI155rMOE1A0Ylod0tcSaj4hHI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YBG4	uniprotkb:Q8IZ83	intact:EBI-2844283|uniprotkb:Q0WK04|uniprotkb:Q7CKQ0|uniprotkb:A0A384LJ06	intact:EBI-1044483|uniprotkb:C9JBH6|uniprotkb:Q86YF0|uniprotkb:Q8IYL4|uniprotkb:Q8TEI8|uniprotkb:B4DLQ1|ensembl:ENSP00000293350.3	psi-mi:a0a5p8ybg4_yerpe(display_long)|uniprotkb:YPO0302(locus name)	psi-mi:a16a1_human(display_long)|uniprotkb:ALDH16A1(gene name)|psi-mi:ALDH16A1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877089|imex:IM-13779-8470	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR018030|interpro:IPR025885|interpro:IPR025949|interpro:IPR043142|refseq:WP_002209081.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR042186|interpro:IPR037224|refseq:YP_002345384.1|panther:PTHR30451(orthology-group)"	"refseq:NP_699160.2|refseq:NP_001138868.1|ensembl:ENSG00000161618.10(gene)|ensembl:ENST00000293350.9(transcript)|go:""GO:0016020""(membrane)|go:""GO:0016620""(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q8IZ83|panther:PTHR11699(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:C8RweNxDibwajstM8qeNKJ2Yisg632	rogid:BoCNAGkgDh2oJaclyaoXr117+iw9606	intact-crc:6EACA1F4969A9682|rigid:nW32GSNdhOYEBhAl5Lmr6ojAmGM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q676U5	uniprotkb:Q8D1L3	intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872.4|ensembl:ENSP00000487542.1	intact:EBI-2848215	psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym)	psi-mi:q8d1l3_yerpe(display_long)|uniprotkb:ilvE(gene name)|psi-mi:ilvE(display_short)|uniprotkb:y0337(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877068|imex:IM-13779-8467	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|ensembl:ENSG00000085978.22(gene)|ensembl:ENSG00000281089.3(gene)|ensembl:ENST00000392017.9(transcript)|ensembl:ENST00000625501.3(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005776""(autophagosome)|go:""GO:0005829""(cytosol)|go:""GO:0005930""(axoneme)|go:""GO:0006501""(C-terminal protein lipidation)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0015031""(protein transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0016237""(microautophagy)|go:""GO:0019787""(ubiquitin-like protein transferase activity)|go:""GO:0021766""(hippocampus development)|go:""GO:0022038""(corpus callosum development)|go:""GO:0030424""(axon)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0034274""(Atg12-Atg5-Atg16 complex)|go:""GO:0034497""(protein localization to phagophore assembly site)|go:""GO:0036020""(endolysosome membrane)|go:""GO:0039689""(negative stranded viral RNA replication)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0051020""(GTPase binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0097225""(sperm midpiece)|go:""GO:0098792""(xenophagy)|go:""GO:0098930""(axonal transport)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0120095""(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR045160|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|rcsb pdb:7F69|rcsb pdb:7W36|rcsb pdb:7XFR|reactome:R-HSA-1632852|dip:DIP-27552N|dip:DIP-50290N|panther:PTHR19878(orthology-group)"	"interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR018300|interpro:IPR005785(Branched-chain amino acid aminotransferase I)|interpro:IPR043131|interpro:IPR043132|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0052655""(L-valine-2-oxoglutarate transaminase activity)|go:""GO:0052656""(L-isoleucine-2-oxoglutarate transaminase activity)|interpro:IPR033939|interpro:IPR036038|interpro:IPR050571"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/13	rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606	rogid:JAIOxo2Y3yD5UWLnGFqrvcdTTQM632	intact-crc:1B3C29D9FACE98C7|rigid:G/fb59Ja2iSfBYpanIA/F3j7LPc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZGK8	uniprotkb:Q8IZ83	intact:EBI-2840206|uniprotkb:Q0WHC9	intact:EBI-1044483|uniprotkb:C9JBH6|uniprotkb:Q86YF0|uniprotkb:Q8IYL4|uniprotkb:Q8TEI8|uniprotkb:B4DLQ1|ensembl:ENSP00000293350.3	psi-mi:uxua_yerpe(display_long)|uniprotkb:uxuA(gene name)|psi-mi:uxuA(display_short)|uniprotkb:D-mannonate hydro-lyase(gene name synonym)|uniprotkb:YPO1283(locus name)|uniprotkb:YP_1308(locus name)|uniprotkb:y2902(locus name)	psi-mi:a16a1_human(display_long)|uniprotkb:ALDH16A1(gene name)|psi-mi:ALDH16A1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877075|imex:IM-13779-8469	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004628(Mannonate dehydratase)|go:""GO:0008198""(ferrous iron binding)|go:""GO:0008927""(mannonate dehydratase activity)|go:""GO:0030145""(manganese ion binding)|go:""GO:0042840""(D-glucuronate catabolic process)|refseq:WP_002208813.1|refseq:YP_002346309.1|interpro:IPR036237|panther:PTHR30387(orthology-group)"	"refseq:NP_699160.2|refseq:NP_001138868.1|ensembl:ENSG00000161618.10(gene)|ensembl:ENST00000293350.9(transcript)|go:""GO:0016020""(membrane)|go:""GO:0016620""(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q8IZ83|panther:PTHR11699(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JhdXu0NB4lbIj/rl4GvHVR+RwwE632	rogid:BoCNAGkgDh2oJaclyaoXr117+iw9606	intact-crc:06BAE5DE122AF00B|rigid:modszxuf6/nfG56SLJGLiDAznMY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IZ83	uniprotkb:Q8ZEL9	intact:EBI-1044483|uniprotkb:C9JBH6|uniprotkb:Q86YF0|uniprotkb:Q8IYL4|uniprotkb:Q8TEI8|uniprotkb:B4DLQ1|ensembl:ENSP00000293350.3	intact:EBI-2858120|uniprotkb:Q0WF17	psi-mi:a16a1_human(display_long)|uniprotkb:ALDH16A1(gene name)|psi-mi:ALDH16A1(display_short)	psi-mi:fadr_yerpe(display_long)|uniprotkb:fadR(gene name)|psi-mi:fadR(display_short)|uniprotkb:YPO2144(locus name)|uniprotkb:y2177(locus name)|uniprotkb:YP_1946(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877096|imex:IM-13779-8466	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_699160.2|refseq:NP_001138868.1|ensembl:ENSG00000161618.10(gene)|ensembl:ENST00000293350.9(transcript)|go:""GO:0016020""(membrane)|go:""GO:0016620""(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q8IZ83|panther:PTHR11699(orthology-group)"	"interpro:IPR014178(Fatty acid response transcription factor FadR)|interpro:IPR008920(Fatty acid responsive transcription factor FadR, C-terminal)|interpro:IPR000524(Bacterial regulatory protein GntR, HTH)|interpro:IPR028374|refseq:WP_002211688.1|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0019217""(regulation of fatty acid metabolic process)|interpro:IPR036388|interpro:IPR036390|refseq:YP_002347121.1|panther:PTHR43537(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BoCNAGkgDh2oJaclyaoXr117+iw9606	rogid:BtgcqSpKLgoqX7IWTz50Z6ZY5/w632	intact-crc:845707DE12779937|rigid:pkcaeyYLAZHr211JY0qmElj8VRw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01903	uniprotkb:Q8ZHK4	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608.2|ensembl:ENSP00000372746.2|ensembl:ENSP00000378786.2|ensembl:ENSP00000402951.2|ensembl:ENSP00000404533.2|ensembl:ENSP00000405295.2|ensembl:ENSP00000410443.2|ensembl:ENSP00000479287.1	intact:EBI-2869479|uniprotkb:Q0WIF1	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	psi-mi:rf2_yerpe(display_long)|uniprotkb:prfB(gene name)|psi-mi:prfB(display_short)|uniprotkb:YPO0889(locus name)|uniprotkb:y3273(locus name)|uniprotkb:YP_3585(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877117|imex:IM-13779-8475	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-6063N|efo:""Orphanet:505""|ensembl:ENSG00000204287.14(gene)|ensembl:ENSG00000206308.11(gene)|ensembl:ENSG00000226260.9(gene)|ensembl:ENSG00000227993.9(gene)|ensembl:ENSG00000228987.9(gene)|ensembl:ENSG00000230726.9(gene)|ensembl:ENSG00000234794.9(gene)|ensembl:ENSG00000277263.1(gene)|ensembl:ENST00000383127.6(transcript)|ensembl:ENST00000383259.6(transcript)|ensembl:ENST00000395388.7(transcript)|ensembl:ENST00000411524.6(transcript)|ensembl:ENST00000414698.6(transcript)|ensembl:ENST00000416883.6(transcript)|ensembl:ENST00000442960.6(transcript)|ensembl:ENST00000613328.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050890""(cognition)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01903|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:1ZGL|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:7N19|rcsb pdb:7NZE|rcsb pdb:7O00|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8CMB|rcsb pdb:8CMC|rcsb pdb:8CMD|rcsb pdb:8CME|rcsb pdb:8CMF|rcsb pdb:8CMG|rcsb pdb:8CMH|rcsb pdb:8CMI|rcsb pdb:8EUQ|rcsb pdb:8PJE|rcsb pdb:8PJF|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:9B7B|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_061984.2|panther:PTHR19944(orthology-group)"	"interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004374(Peptide chain release factor 2)|go:""GO:0005737""(cytoplasm)|go:""GO:0016149""(translation release factor activity, codon specific)|go:""GO:0075523""(viral translational frameshifting)|interpro:IPR045853|panther:PTHR43116(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	rogid:a1t0nAHItdlbOUGmg7DndMpsYpA632	intact-crc:4185C08924C3BB60|rigid:vmHAV3YzEY4Z6ZyJXnZPutTcTbs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13542	uniprotkb:Q8Z9S7	intact:EBI-935137|ensembl:ENSP00000362314.4	intact:EBI-2843785|uniprotkb:Q74PA2|uniprotkb:Q0W9R8|uniprotkb:Q8CZF5	psi-mi:4ebp2_human(display_long)|uniprotkb:EIF4EBP2(gene name)|psi-mi:EIF4EBP2(display_short)	psi-mi:glmu_yerpe(display_long)|uniprotkb:glmU(gene name)|psi-mi:glmU(display_short)|uniprotkb:YPO4119(locus name)|uniprotkb:y4133(locus name)|uniprotkb:YP_4026(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877110|imex:IM-13779-8471	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004087.1|ensembl:ENSG00000148730.7(gene)|ensembl:ENST00000373218.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006412""(translation)|go:""GO:0007613""(memory)|go:""GO:0008190""(eukaryotic initiation factor 4E binding)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0030371""(translation repressor activity)|go:""GO:0031929""(TOR signaling)|go:""GO:0035176""(social behavior)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0071598""(neuronal ribonucleoprotein granule)|go:""GO:0098794""(postsynapse)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|mint:Q13542|rcsb pdb:2MX4|rcsb pdb:3AM7|dip:DIP-36572N|panther:PTHR12669(orthology-group)"	"rcsb pdb:4FCE|interpro:IPR029044|interpro:IPR005882(UDP-N-acetylglucosamine pyrophosphorylase)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR018357|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR025877|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003977""(UDP-N-acetylglucosamine diphosphorylase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019134""(glucosamine-1-phosphate N-acetyltransferase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR038009|refseq:WP_002215550.1|refseq:YP_002348970.1|interpro:IPR050065|panther:PTHR43584(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/30	rogid:EDzLBqy7pJvo45a3b6pHWOlRRQY9606	rogid:9qnSgGL+fCmXV2kMl5dYnODFWqw632	intact-crc:94182FF66A4D1DAA|rigid:rt4fik3bA6N/5f8o6xrR7cVGC78	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01903	uniprotkb:A0A2U2GYS8	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608.2|ensembl:ENSP00000372746.2|ensembl:ENSP00000378786.2|ensembl:ENSP00000402951.2|ensembl:ENSP00000404533.2|ensembl:ENSP00000405295.2|ensembl:ENSP00000410443.2|ensembl:ENSP00000479287.1	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877131|imex:IM-13779-8472	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-6063N|efo:""Orphanet:505""|ensembl:ENSG00000204287.14(gene)|ensembl:ENSG00000206308.11(gene)|ensembl:ENSG00000226260.9(gene)|ensembl:ENSG00000227993.9(gene)|ensembl:ENSG00000228987.9(gene)|ensembl:ENSG00000230726.9(gene)|ensembl:ENSG00000234794.9(gene)|ensembl:ENSG00000277263.1(gene)|ensembl:ENST00000383127.6(transcript)|ensembl:ENST00000383259.6(transcript)|ensembl:ENST00000395388.7(transcript)|ensembl:ENST00000411524.6(transcript)|ensembl:ENST00000414698.6(transcript)|ensembl:ENST00000416883.6(transcript)|ensembl:ENST00000442960.6(transcript)|ensembl:ENST00000613328.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050890""(cognition)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01903|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:1ZGL|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:7N19|rcsb pdb:7NZE|rcsb pdb:7O00|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8CMB|rcsb pdb:8CMC|rcsb pdb:8CMD|rcsb pdb:8CME|rcsb pdb:8CMF|rcsb pdb:8CMG|rcsb pdb:8CMH|rcsb pdb:8CMI|rcsb pdb:8EUQ|rcsb pdb:8PJE|rcsb pdb:8PJF|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:9B7B|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_061984.2|panther:PTHR19944(orthology-group)"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	intact-crc:9795C62A86891599|rigid:DmWZuZbp+nRwa3CBFj2ZAP+bnHk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01903	uniprotkb:A0A6M0NFD2	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608.2|ensembl:ENSP00000372746.2|ensembl:ENSP00000378786.2|ensembl:ENSP00000402951.2|ensembl:ENSP00000404533.2|ensembl:ENSP00000405295.2|ensembl:ENSP00000410443.2|ensembl:ENSP00000479287.1	intact:EBI-2845236	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	psi-mi:a0a6m0nfd2_yerpe(display_long)|uniprotkb:y2123(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877124|imex:IM-13779-8473	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-6063N|efo:""Orphanet:505""|ensembl:ENSG00000204287.14(gene)|ensembl:ENSG00000206308.11(gene)|ensembl:ENSG00000226260.9(gene)|ensembl:ENSG00000227993.9(gene)|ensembl:ENSG00000228987.9(gene)|ensembl:ENSG00000230726.9(gene)|ensembl:ENSG00000234794.9(gene)|ensembl:ENSG00000277263.1(gene)|ensembl:ENST00000383127.6(transcript)|ensembl:ENST00000383259.6(transcript)|ensembl:ENST00000395388.7(transcript)|ensembl:ENST00000411524.6(transcript)|ensembl:ENST00000414698.6(transcript)|ensembl:ENST00000416883.6(transcript)|ensembl:ENST00000442960.6(transcript)|ensembl:ENST00000613328.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050890""(cognition)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01903|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:1ZGL|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:7N19|rcsb pdb:7NZE|rcsb pdb:7O00|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8CMB|rcsb pdb:8CMC|rcsb pdb:8CMD|rcsb pdb:8CME|rcsb pdb:8CMF|rcsb pdb:8CMG|rcsb pdb:8CMH|rcsb pdb:8CMI|rcsb pdb:8EUQ|rcsb pdb:8PJE|rcsb pdb:8PJF|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:9B7B|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_061984.2|panther:PTHR19944(orthology-group)"	interpro:IPR017030(Virulence effector, SrfC)|uniprotkb:A0A6B3SX50(uniprot-removed-ac)|refseq:WP_002223600.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	rogid:LSgmQHoXt7/pDPFzf/ovmUXx4gY632	intact-crc:2DCA1911F4A3E98C|rigid:OHvd9KnuO0AgMCX1dVEYT2PlyAE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0PJ79	uniprotkb:Q8CZQ3	intact:EBI-2839299	intact:EBI-2849368|uniprotkb:Q74Q61	psi-mi:a0pj79_human(display_long)|uniprotkb:MRPL1(gene name)|psi-mi:MRPL1(display_short)	psi-mi:q8czq3_yerpe(display_long)|uniprotkb:ilvI(gene name)|psi-mi:ilvI(display_short)|uniprotkb:y3640(locus name)|uniprotkb:YP_3646(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877103|imex:IM-13779-8474	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005879(Ribosomal protein L1, mitochondrial)|interpro:IPR023674|go:""GO:0003723""(RNA binding)|go:""GO:0003735""(structural constituent of ribosome)|go:""GO:0005739""(mitochondrion)|go:""GO:0006412""(translation)|go:""GO:0015934""(large ribosomal subunit)|interpro:IPR028364|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)"	"interpro:IPR039368|interpro:IPR012846(Acetolactate synthase, large subunit, biosynthetic)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR029035|interpro:IPR029061|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003984""(acetolactate synthase activity)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR045229"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GOaEd5hODq/1j2dE6MzLk9tuJK09606	rogid:HjawDXJtJf287797Q9KXxlU93ng632	intact-crc:8EA362D0751AEA5A|rigid:UoCyQtdyIHfmBU8SGfjPeZdH8D0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P28068	uniprotkb:A0A7D9NLK2	intact:EBI-2877138|ensembl:ENSP00000372718.2|ensembl:ENSP00000378723.3|ensembl:ENSP00000393646.2|ensembl:ENSP00000398890.2|ensembl:ENSP00000408453.2|ensembl:ENSP00000411321.2|ensembl:ENSP00000413471.2|ensembl:ENSP00000414817.2|uniprotkb:Q13012|uniprotkb:Q5SNZ8|uniprotkb:Q58ZE2|uniprotkb:O77936|uniprotkb:Q29751|uniprotkb:Q5STC4|uniprotkb:Q9XRX2	intact:EBI-2842776	psi-mi:dmb_human(display_long)|uniprotkb:HLA-DMB(gene name)|psi-mi:HLA-DMB(display_short)|uniprotkb:DMB(gene name synonym)|uniprotkb:RING7(gene name synonym)|uniprotkb:MHC class II antigen DMB(gene name synonym)|uniprotkb:Really interesting new gene 7 protein(gene name synonym)	psi-mi:a0a7d9nlk2_yerpe(display_long)|uniprotkb:ORF99(gene name)|psi-mi:ORF99(display_short)|uniprotkb:Y1060(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877149|imex:IM-13779-8476	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000226264.10(gene)|ensembl:ENSG00000234154.10(gene)|ensembl:ENSG00000239329.8(gene)|ensembl:ENSG00000241296.8(gene)|ensembl:ENSG00000241674.8(gene)|ensembl:ENSG00000242092.8(gene)|ensembl:ENSG00000242386.8(gene)|ensembl:ENSG00000242574.9(gene)|ensembl:ENST00000383231.6(transcript)|ensembl:ENST00000395312.7(transcript)|ensembl:ENST00000412948.6(transcript)|ensembl:ENST00000418107.3(transcript)|ensembl:ENST00000424822.6(transcript)|ensembl:ENST00000428420.6(transcript)|ensembl:ENST00000440078.6(transcript)|ensembl:ENST00000450897.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002399""(MHC class II protein complex assembly)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:2001190""(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P28068|rcsb pdb:1HDM|rcsb pdb:2BC4|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4I0P|reactome:R-HSA-2132295|refseq:NP_002109.2|dip:DIP-6185N|panther:PTHR19944(orthology-group)"	"refseq:WP_002224265.1|refseq:YP_093964.1|uniprotkb:A0A5K1VD91(uniprot-removed-ac)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:GUK9uGNN8YKoxL68SGAFTviNj4o9606	rogid:drpdmgWm7Xi1tzOHiVuDwatPqrI632	intact-crc:ABB52FA1D1BE195C|rigid:X7jZxiQu2js0TQbUOO0R0ekD21A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9F287	uniprotkb:P01911	intact:EBI-2854744|uniprotkb:Q7CGE2|uniprotkb:A0A384KA49|uniprotkb:A0A1U8QHS7|uniprotkb:A0A454XLL2	intact:EBI-1033104|uniprotkb:O19717|uniprotkb:O19739|uniprotkb:P13759|uniprotkb:Q29875|uniprotkb:Q30145|uniprotkb:Q9GIX9|uniprotkb:Q9GIY4|uniprotkb:Q9MY13|uniprotkb:Q9XRY5|ensembl:ENSP00000353099.5|uniprotkb:A0MWF2|uniprotkb:A0N0W1|uniprotkb:A2ICT1|uniprotkb:A2TGX3|uniprotkb:A4F5N0|uniprotkb:A4ZXA5|uniprotkb:A4ZXA6|uniprotkb:A4ZY86|uniprotkb:A5H000|uniprotkb:A5HKN8|uniprotkb:A7DZP9|uniprotkb:A7LA26|uniprotkb:A7UHG2|uniprotkb:A7X5B1|uniprotkb:A7X5B7|uniprotkb:A7X5E0|uniprotkb:A7X5E6|uniprotkb:A7X5H8|uniprotkb:A7X5J4|uniprotkb:A7X5K7|uniprotkb:A8K098|uniprotkb:A8YQE9|uniprotkb:A9JPG0|uniprotkb:B0BK85|uniprotkb:B1GWE7|uniprotkb:B2CR03|uniprotkb:B0LUZ6|uniprotkb:B0UYW1|uniprotkb:B2LVF9|uniprotkb:B2NJ29|uniprotkb:B2ZCY1|uniprotkb:B3VTP8|uniprotkb:B3VTQ3|uniprotkb:B5A8Y2|uniprotkb:B5A8Y3|uniprotkb:C0LAB5|uniprotkb:B5B8U0|uniprotkb:B5B9V5|uniprotkb:B5B9V6|uniprotkb:B5LZ25|uniprotkb:B5QSK8|uniprotkb:B6VCX2|uniprotkb:B6VEL9|uniprotkb:B7UDB2|uniprotkb:B9VRA4|uniprotkb:B9X248|uniprotkb:Q0PGR5|uniprotkb:O02876|uniprotkb:O02930|uniprotkb:O19585|uniprotkb:O19718|uniprotkb:O19788|uniprotkb:O46699|uniprotkb:O46793|uniprotkb:O46872|uniprotkb:O62869|uniprotkb:O62889|uniprotkb:O77969|uniprotkb:O78047|uniprotkb:O78210|uniprotkb:O98212|uniprotkb:P01912|uniprotkb:P01914|uniprotkb:P04229|uniprotkb:P13758|uniprotkb:P13760|uniprotkb:P13761|uniprotkb:P20039|uniprotkb:P79545|uniprotkb:Q06662|uniprotkb:Q0PQ39|uniprotkb:Q14280|uniprotkb:Q14QT2|uniprotkb:Q155F7|uniprotkb:Q19AF2|uniprotkb:Q19K86|uniprotkb:Q1AP33|uniprotkb:Q1G0Z9|uniprotkb:Q1JRP3|uniprotkb:Q1KLJ6|uniprotkb:Q27PR6|uniprotkb:Q27PR7|uniprotkb:Q29673|uniprotkb:Q29720|uniprotkb:Q29722|uniprotkb:Q29734|uniprotkb:Q29770|uniprotkb:Q29771|uniprotkb:Q768U2|uniprotkb:Q29772|uniprotkb:Q29790|uniprotkb:Q29792|uniprotkb:Q29800|uniprotkb:Q29806|uniprotkb:Q29833|uniprotkb:Q29874|uniprotkb:Q29886|uniprotkb:Q29968|uniprotkb:Q29974|uniprotkb:Q29975|uniprotkb:Q2A120|uniprotkb:Q2HZE5|uniprotkb:Q2L9H4|uniprotkb:Q2LE76|uniprotkb:Q2MF40|uniprotkb:Q2MJA6|uniprotkb:Q2MZ92|uniprotkb:Q2VQU1|uniprotkb:Q2YHQ2|uniprotkb:Q30006|uniprotkb:Q30108|uniprotkb:Q30112|uniprotkb:Q30115|uniprotkb:Q30116|uniprotkb:Q30117|uniprotkb:Q30120|uniprotkb:Q30134|uniprotkb:Q30142|uniprotkb:Q30149|uniprotkb:Q30159|uniprotkb:Q30166|uniprotkb:Q30167|uniprotkb:Q30200|uniprotkb:Q307W5|uniprotkb:Q31636|uniprotkb:Q32MY7|uniprotkb:Q3HUP9|uniprotkb:Q3KTM1|uniprotkb:Q3LA84|uniprotkb:Q3LA87|uniprotkb:Q3LA88|uniprotkb:Q3LA89|uniprotkb:Q3LA90|uniprotkb:Q3LA91|uniprotkb:Q3LA92|uniprotkb:Q3LA93|uniprotkb:Q3LA94|uniprotkb:Q3LA95|uniprotkb:Q3LA96|uniprotkb:Q3LA97|uniprotkb:Q3LA98|uniprotkb:Q3LA99|uniprotkb:Q3LAA0|uniprotkb:Q3LAA1|uniprotkb:Q3LAA2|uniprotkb:Q3MQ60|uniprotkb:Q3T919|uniprotkb:Q4PRC3|uniprotkb:Q4PRC5|uniprotkb:Q4VZY7|uniprotkb:Q53IG1|uniprotkb:Q56FN9|uniprotkb:Q56FP1|uniprotkb:Q56FP2|uniprotkb:Q56FP3|uniprotkb:Q58F52|uniprotkb:Q5BM92|uniprotkb:Q5EER6|uniprotkb:Q5K3W2|uniprotkb:Q5NDB9|uniprotkb:Q5U9W6|uniprotkb:Q5UBA2|uniprotkb:Q5UT58|uniprotkb:Q5W3L4|uniprotkb:Q5Y7A7|uniprotkb:Q5Y7B0|uniprotkb:Q5Y7B9|uniprotkb:Q5Y7E9|uniprotkb:Q5Y7G0|uniprotkb:Q683P7|uniprotkb:Q6REE2|uniprotkb:Q6T865|uniprotkb:Q6U387|uniprotkb:Q701T1|uniprotkb:Q70GL2|uniprotkb:Q70Q85|uniprotkb:Q768U4|uniprotkb:Q7M2H4|uniprotkb:Q7YNY9|uniprotkb:Q7YP03|uniprotkb:Q7YP04|uniprotkb:Q7YQ26|uniprotkb:Q7YQA3|uniprotkb:Q7YQA5|uniprotkb:Q860D8|uniprotkb:Q860D9|uniprotkb:Q860E5|uniprotkb:Q860H8|uniprotkb:Q860S0|uniprotkb:Q860Z3|uniprotkb:Q861G6|uniprotkb:Q861H0|uniprotkb:Q861H4|uniprotkb:Q861H5|uniprotkb:Q861H7|uniprotkb:Q861H8|uniprotkb:Q8HWQ6|uniprotkb:Q8MH59|uniprotkb:Q8MH60|uniprotkb:Q8WLU3|uniprotkb:Q8WMA0|uniprotkb:Q95348|uniprotkb:Q95383|uniprotkb:Q95389|uniprotkb:Q95461|uniprotkb:Q95HK1|uniprotkb:Q95HL0|uniprotkb:Q95HL1|uniprotkb:Q95IE3|uniprotkb:Q95IG2|uniprotkb:Q95IT6|uniprotkb:Q96HZ9|uniprotkb:Q9BCL7|uniprotkb:Q9BCP0|uniprotkb:Q9BCP1|uniprotkb:Q9BCP2|uniprotkb:Q9BCP5|uniprotkb:Q9BD21|uniprotkb:Q9BD33|uniprotkb:Q9BD40|uniprotkb:Q9GIK5|uniprotkb:Q9GIL5|uniprotkb:Q9GIL6|uniprotkb:Q9GIP3|uniprotkb:Q9GIX8|uniprotkb:Q9GIY0|uniprotkb:Q9GIY1|uniprotkb:Q9GIY2|intact:EBI-3866098|intact:EBI-13953066|uniprotkb:Q9GIY3|uniprotkb:Q9GJ25|uniprotkb:Q9GJ56|uniprotkb:Q9GJ57|uniprotkb:Q9GJ58|uniprotkb:Q9GJ60|uniprotkb:Q9GJF8|uniprotkb:Q9GJF9|uniprotkb:Q9GJG0|uniprotkb:Q9MXZ0|uniprotkb:Q9MXZ5|uniprotkb:Q9MY45|uniprotkb:Q9MY56|uniprotkb:Q9MYF5|uniprotkb:Q9TPB6|uniprotkb:Q9TPW1|uniprotkb:Q9TPW3|uniprotkb:Q9TPW9|uniprotkb:Q9TPX4|uniprotkb:Q9TQ37|uniprotkb:Q9TQ91|uniprotkb:Q9TQE0|uniprotkb:Q9UBY1|uniprotkb:Q9UIM9|uniprotkb:Q9UIN0|uniprotkb:Q9XRX1|uniprotkb:Q9XRY4|uniprotkb:Q9Y453|uniprotkb:Q9Y4H7|intact:EBI-13953170|intact:EBI-2877159	psi-mi:q9f287_yerpe(display_long)|uniprotkb:yapF(gene name)|psi-mi:yapF(display_short)|uniprotkb:YPO0606(locus name)	psi-mi:drb1_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)|uniprotkb:Human leukocyte antigen DRB1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877156|imex:IM-13779-8478	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR005546(Autotransporter beta-domain)|refseq:WP_002210389.1|interpro:IPR036709|refseq:YP_002345675.1	"ensembl:ENSG00000196126.12(gene)|ensembl:ENST00000360004.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002842""(positive regulation of T cell mediated immune response to tumor cell)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0008544""(epidermis development)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032653""(regulation of interleukin-10 production)|go:""GO:0032673""(regulation of interleukin-4 production)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0035774""(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0042088""(T-helper 1 type immune response)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0051262""(protein tetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01911|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FYT|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6HBY|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_001230894.1|refseq:NP_002115.2|refseq:XP_011546040.1|efo:""Orphanet:2073""|efo:""Orphanet:220393""|efo:""Orphanet:220402""|efo:""Orphanet:220407""|efo:""Orphanet:397""|efo:""Orphanet:477738""|efo:""Orphanet:536""|efo:""Orphanet:545""|efo:""Orphanet:703""|efo:""Orphanet:747""|efo:""Orphanet:797""|efo:""Orphanet:83465""|efo:""Orphanet:85414""|panther:PTHR19944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uIQ9881A2N1D063pjSQtEbbJqNs632	rogid:YdQX0KNIxO5tYjgm6hdRRZfNlk49606	intact-crc:390F42CE0729EBCE|rigid:sp7veR5ZuMWW3b9Fb0E8RYVGQHs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9RID8	uniprotkb:P30153	intact:EBI-2859217|uniprotkb:A0A3G5LBF7|uniprotkb:A0A384LNJ8|uniprotkb:Q7BTU6|uniprotkb:A0A2S9PDW1|uniprotkb:A0A380PG85	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804.6	psi-mi:q9rid8_yerpe(display_long)|uniprotkb:YPMT1.33(locus name)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877253|imex:IM-13779-8477	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002214134.1|refseq:NP_857670.1|interpro:IPR003223(Flagellin phase1 repressor)|refseq:NP_395371.1|go:""GO:0003700""(DNA-binding transcription factor activity)"	"ensembl:ENSG00000105568.19(gene)|ensembl:ENST00000322088.11(transcript)|go:""GO:0000159""(protein phosphatase type 2A complex)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007143""(female meiotic nuclear division)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0030425""(dendrite)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0040008""(regulation of growth)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0045595""(regulation of cell differentiation)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051232""(meiotic spindle elongation)|go:""GO:0051306""(mitotic sister chromatid separation)|go:""GO:0051754""(meiotic sister chromatid cohesion, centromeric)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090443""(FAR/SIN/STRIPAK complex)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1903538""(regulation of meiotic cell cycle process involved in oocyte maturation)|go:""GO:1990405""(protein antigen binding)|go:""GO:2001241""(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR051023|interpro:IPR054573|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|rcsb pdb:7PKS|rcsb pdb:7SOY|rcsb pdb:7YCX|rcsb pdb:8RBX|rcsb pdb:8RBZ|rcsb pdb:8RC4|rcsb pdb:8SO0|rcsb pdb:8TTB|rcsb pdb:8TWE|rcsb pdb:8TWI|rcsb pdb:8U1X|rcsb pdb:8U89|rcsb pdb:8UWB|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|reactome:R-HSA-9833482|reactome:R-HSA-9860927|refseq:NP_055040.2|efo:""Orphanet:457284""|dip:DIP-29394N|ensembl:ENSP00000324804.6|panther:PTHR10648(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Gai8ohATJMOb+TpT/VpPGU9fdDw632	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:0AC3337D4EAED047|rigid:GQvyu2F8ePIpENrlru+/8w6As1M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4AWL6	uniprotkb:Q15173	intact:EBI-2839922|uniprotkb:Q74PS8|uniprotkb:A0A0H2W8P4|uniprotkb:Q7CL98|uniprotkb:A0A384KVQ8	intact:EBI-1369497|uniprotkb:Q13853|ensembl:ENSP00000164133.2	psi-mi:a0a3n4awl6_yerpe(display_long)|uniprotkb:arcB(gene name)|psi-mi:arcB(display_short)|uniprotkb:YPO3555(locus name)	psi-mi:2a5b_human(display_long)|uniprotkb:PPP2R5B(gene name)|psi-mi:PPP2R5B(display_short)|uniprotkb:PP2A B subunit isoform B'-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-beta(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877260|imex:IM-13779-8479	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR008207(""Signal transduction histidine kinase, phosphotransfer (Hpt) region"")|interpro:IPR014409(Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR027460|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR040642|refseq:WP_002210142.1|interpro:IPR035965|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|refseq:YP_002348442.1|panther:PTHR43719(orthology-group)"	"ensembl:ENSG00000068971.14(gene)|ensembl:ENST00000164133.7(transcript)|go:""GO:0000159""(protein phosphatase type 2A complex)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051388""(positive regulation of neurotrophin TRK receptor signaling pathway)|go:""GO:0070317""(negative regulation of G0 to G1 transition)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072542""(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q15173|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-381038|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_006235.1|panther:PTHR10257(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2Xj+2T9RNcjzPI8FYYaZmDGKNBk632	rogid:aYC6Y4axPUXmrHoGUp7NMQP4p0Q9606	intact-crc:48375F8FEE55F462|rigid:VW/N6AQhHMx7K9umP82o8O0c0zA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10321	uniprotkb:Q8CZQ3	intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402.5	intact:EBI-2849368|uniprotkb:Q74Q61	psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)	psi-mi:q8czq3_yerpe(display_long)|uniprotkb:ilvI(gene name)|psi-mi:ilvI(display_short)|uniprotkb:y3640(locus name)|uniprotkb:YP_3646(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877274|imex:IM-13779-8482	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204525.18(gene)|ensembl:ENST00000376228.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_002108.4|efo:""Orphanet:585909""|panther:PTHR16675(orthology-group)"	"interpro:IPR039368|interpro:IPR012846(Acetolactate synthase, large subunit, biosynthetic)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR029035|interpro:IPR029061|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003984""(acetolactate synthase activity)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR045229"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606	rogid:HjawDXJtJf287797Q9KXxlU93ng632	intact-crc:C0F91362C6655FE0|rigid:V39s95CV6wLMIKw75QA3zcCRyJ4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10321	uniprotkb:Q8ZIX0	intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402.5	intact:EBI-2843533|uniprotkb:Q0WJU5	psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)	psi-mi:rsga_yerpe(display_long)|uniprotkb:rsgA(gene name)|psi-mi:rsgA(display_short)|uniprotkb:YPO0365(locus name)|uniprotkb:y0622(locus name)|uniprotkb:YP_0520(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877288|imex:IM-13779-8483	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204525.18(gene)|ensembl:ENST00000376228.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_002108.4|efo:""Orphanet:585909""|panther:PTHR16675(orthology-group)"	"interpro:IPR010914(EngC GTPase)|interpro:IPR004881(GTPase EngC)|interpro:IPR027417|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0019843""(rRNA binding)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0046872""(metal ion binding)|interpro:IPR030378|refseq:WP_002209142.1|refseq:YP_002345443.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR32120(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606	rogid:rH6QCtn1mhukog75yh2CbD5VMPg632	intact-crc:2EEB718BC682E042|rigid:ssD0t9fqFN4po0xiv+T6576OaDA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4AWL6	uniprotkb:P10321	intact:EBI-2839922|uniprotkb:Q74PS8|uniprotkb:A0A0H2W8P4|uniprotkb:Q7CL98|uniprotkb:A0A384KVQ8	intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402.5	psi-mi:a0a3n4awl6_yerpe(display_long)|uniprotkb:arcB(gene name)|psi-mi:arcB(display_short)|uniprotkb:YPO3555(locus name)	psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877281|imex:IM-13779-8480	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR008207(""Signal transduction histidine kinase, phosphotransfer (Hpt) region"")|interpro:IPR014409(Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR027460|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR040642|refseq:WP_002210142.1|interpro:IPR035965|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|refseq:YP_002348442.1|panther:PTHR43719(orthology-group)"	"ensembl:ENSG00000204525.18(gene)|ensembl:ENST00000376228.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_002108.4|efo:""Orphanet:585909""|panther:PTHR16675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:2Xj+2T9RNcjzPI8FYYaZmDGKNBk632	rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606	intact-crc:98EED4795A552A49|rigid:zS61M0fj/4ocseT1iS1hXk/cmP8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10321	uniprotkb:Q8D1Q0	intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402.5	intact:EBI-2842423	psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)	psi-mi:q8d1q0_yerpe(display_long)|uniprotkb:gabD(gene name)|psi-mi:gabD(display_short)|uniprotkb:gabD_1(gene name synonym)|uniprotkb:NCTC5923_00695(orf name)|uniprotkb:y0176(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877267|imex:IM-13779-8481	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204525.18(gene)|ensembl:ENST00000376228.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_002108.4|efo:""Orphanet:585909""|panther:PTHR16675(orthology-group)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR029510|go:""GO:0036243""(""succinate-semialdehyde dehydrogenase (NADP+) activity"")|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR050740"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606	rogid:txdyWoCIYMZColLNszJEOPdNYNk632	intact-crc:F51B5A35C6804B57|rigid:n0ySg0Qfr/2okQ4WjtaCiA7RnNg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG3	uniprotkb:P01889	intact:EBI-2854674|uniprotkb:Q8CZV6|uniprotkb:Q0WIA5	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	psi-mi:y936_yerpe(display_long)|uniprotkb:YPO0936(locus name)|uniprotkb:y3322(locus name)|uniprotkb:YP_3506(locus name)	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877309|imex:IM-13779-8485	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003774(Protein of unknown function DUF179)|refseq:WP_002209977.1|go:""GO:0005829""(cytosol)|refseq:YP_002345983.1|panther:PTHR30327(orthology-group)"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mUyeIgl5pBHZwbB6q7lbZ88jLW0632	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	intact-crc:EF65B3FC3B7EFBD7|rigid:rRLvHZAN+05b5PvHG4t+YcybGOE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZM8	uniprotkb:P01889	intact:EBI-2848309	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	psi-mi:q8czm8_yerpe(display_long)|uniprotkb:ptsA(gene name)|psi-mi:ptsA(display_short)|uniprotkb:y3776(locus name)	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877323|imex:IM-13779-8488	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR018274|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR023151|interpro:IPR006318(Phosphoenolpyruvate-protein phosphotransferase)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR008731(Phosphotransferase system, PEP-utilising enzyme, N-terminal)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|go:""GO:0005737""(cytoplasm)|go:""GO:0008965""(phosphoenolpyruvate-protein phosphotransferase activity)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR040442|interpro:IPR035895|interpro:IPR036618|interpro:IPR036637|interpro:IPR050499"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yFrXLYA0rYHKZA16/O8hjY0IDfU632	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	intact-crc:9E39A015397E5AE3|rigid:C36Av6zTTS77k9O0TES5N/bwvVo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBN6	uniprotkb:P10321	intact:EBI-2845174|uniprotkb:Q0WBS4|uniprotkb:Q8D198|uniprotkb:Q74XS5	intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402.5	psi-mi:cysj_yerpe(display_long)|uniprotkb:cysJ(gene name)|psi-mi:cysJ(display_short)|uniprotkb:YPO3372(locus name)|uniprotkb:y0818(locus name)|uniprotkb:YP_0314(locus name)	psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877295|imex:IM-13779-8487	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010199(Sulphite reductase [NADPH] flavoprotein, alpha chain)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR017927|interpro:IPR001094(Flavodoxin-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR017938|interpro:IPR039261|interpro:IPR029039|interpro:IPR029758|refseq:WP_002209381.1|go:""GO:0000103""(sulfate assimilation)|go:""GO:0004783""(""sulfite reductase (NADPH) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0010181""(FMN binding)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0019344""(cysteine biosynthetic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070814""(hydrogen sulfide biosynthetic process)|interpro:IPR023173|refseq:YP_002348264.1|panther:PTHR19384(orthology-group)"	"ensembl:ENSG00000204525.18(gene)|ensembl:ENST00000376228.10(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_002108.4|efo:""Orphanet:585909""|panther:PTHR16675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:/eQRgxmu+tsNIMHFJ+J0UIYifNc632	rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606	intact-crc:57516A8BC74CE4A3|rigid:69NaPo9bMSrFX+GzNVCzzUCk5vs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01889	uniprotkb:Q8D014	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	intact:EBI-2840312|uniprotkb:Q74WE9	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:q8d014_yerpe(display_long)|uniprotkb:nrdB(gene name)|psi-mi:nrdB(display_short)|uniprotkb:y2975(locus name)|uniprotkb:YP_0924(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877316|imex:IM-13779-8484	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"interpro:IPR033909|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|go:""GO:0004748""(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:""GO:0009263""(deoxyribonucleotide biosynthetic process)|interpro:IPR030475|interpro:IPR012348(Ribonucleotide reductase-related)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	rogid:cQYray4oIRTe9sYOcO6GpVOCuBc632	intact-crc:111A98423AFB2D82|rigid:qu2w1F7cC3WFuqw7JoZJrorXi5Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01889	uniprotkb:P68587	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	intact:EBI-2844901|uniprotkb:P40295	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877302|imex:IM-13779-8486	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	intact-crc:795820AA496D9633|rigid:Aa+28TM0F4759C8Ikl6OfUkQXIQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01889	uniprotkb:Q7CJM9	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	intact:EBI-2860051|uniprotkb:Q74S81	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	"psi-mi:rlmn_yerpe(display_long)|uniprotkb:rlmN(gene name)|psi-mi:rlmN(display_short)|uniprotkb:""23S rRNA (adenine(2503)-C(2))-methyltransferase""(gene name synonym)|uniprotkb:23S rRNA m2A2503 methyltransferase(gene name synonym)|uniprotkb:Ribosomal RNA large subunit methyltransferase N(gene name synonym)|uniprotkb:""tRNA (adenine(37)-C(2))-methyltransferase""(gene name synonym)|uniprotkb:tRNA m2A37 methyltransferase(gene name synonym)|uniprotkb:YPO2882(locus name)|uniprotkb:YP_2748(locus name)|uniprotkb:y1350(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877337|imex:IM-13779-8491	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"refseq:YP_002347817.1|interpro:IPR004383(Conserved hypothetical protein CHP00048)|interpro:IPR007197(Radical SAM)|interpro:IPR040072|refseq:WP_002209820.1|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR027492|go:""GO:0000049""(tRNA binding)|go:""GO:0002935""(""tRNA (adenine(37)-C2)-methyltransferase activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0019843""(rRNA binding)|go:""GO:0030488""(tRNA methylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0070040""(""rRNA (adenine(2503)-C2-)-methyltransferase activity"")|go:""GO:0070475""(rRNA base methylation)|interpro:IPR048641|panther:PTHR30544(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	rogid:kG8F68TmWQ35toLNiP51mzTTqgU632	intact-crc:407E04ECE622A055|rigid:gHTi1jkGHWKYt53IyhsG39fGYg8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLC4	uniprotkb:P01889	intact:EBI-2844860	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	psi-mi:q8clc4_yerpe(display_long)|uniprotkb:y1644(locus name)	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877330|imex:IM-13779-8490	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR004375(Conserved hypothetical protein CHP00022)|interpro:IPR037012	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bRggnpBtWSjyBJTLgvdTftsIYl4632	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	intact-crc:C98F96153AE97530|rigid:VpCJzS4bGFG1J+B4O25V2U0lf1c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A454XXH7	uniprotkb:P01889	intact:EBI-2851240|uniprotkb:Q74Y15|uniprotkb:A0A0H2W158|uniprotkb:Q7CFV5|uniprotkb:A0A384K924	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	psi-mi:a0a454xxh7_yerpe(display_long)|uniprotkb:YPO0168(locus name)	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877351|imex:IM-13779-8492	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR027417|refseq:WP_002215686.1|interpro:IPR033186|refseq:YP_002345254.1|interpro:IPR051162|panther:PTHR30121(orthology-group)	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7T8Io5VjMpoAGWF393x9GYtAK2w632	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	intact-crc:9A24D31244658032|rigid:1K2BF9E/4kNNlC0TuQ4dkyesjaQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01889	uniprotkb:A0A7Y8RFP1	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	intact:EBI-2854011|uniprotkb:Q74VT1|uniprotkb:Q0WH27|uniprotkb:A0A0H2W345|uniprotkb:Q7CHJ5|uniprotkb:A0A384L578	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:a0a7y8rfp1_yerpe(display_long)|uniprotkb:YPO1388(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877344|imex:IM-13779-8489	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"interpro:IPR005594(YadA-like, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|refseq:YP_002346411.1|interpro:IPR045584"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	rogid:p3FK6eF6RqucVMsp7QfWajIkzjw632	intact-crc:6C9C6750BD1768C3|rigid:CRDWxA7RhcEGoxxfDfNoHY+YZXc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04439	uniprotkb:A0A2S9PLS3	intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155|ensembl:ENSP00000366005.5|ensembl:ENSP00000379873.1|ensembl:ENSP00000516612.1|ensembl:ENSP00000516614.1|ensembl:ENSP00000516616.1	intact:EBI-2841789|uniprotkb:Q74RP0|uniprotkb:A0A384KVM3|uniprotkb:Q0WJ02|uniprotkb:Q7CGH6	psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym)	psi-mi:a0a2s9pls3_yerpe(display_long)|uniprotkb:nfxD(gene name)|psi-mi:nfxD(display_short)|uniprotkb:Topoisomerase IV subunit B(gene name synonym)|uniprotkb:parE(gene name synonym)|uniprotkb:YPO0668(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877379|imex:IM-13779-8493	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:179""|ensembl:ENSG00000206503.15(gene)|ensembl:ENST00000376809.10(transcript)|ensembl:ENST00000396634.5(transcript)|ensembl:ENST00000706901.1(transcript)|ensembl:ENST00000706903.1(transcript)|ensembl:ENST00000706905.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002419""(T cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002485""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0003723""(RNA binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0062061""(TAP complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2000568""(positive regulation of memory T cell activation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WJ5|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7MLE|rcsb pdb:7PHR|rcsb pdb:7QPD|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7STF|rcsb pdb:7UC5|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|rcsb pdb:8DVG|rcsb pdb:8RYM|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_001229687.1|refseq:NP_002107.3|ensembl:ENSP00000366005.5|ensembl:ENSP00000379873.1|ensembl:ENSP00000516612.1|ensembl:ENSP00000516614.1|ensembl:ENSP00000516616.1|panther:PTHR16675(orthology-group)"	"interpro:IPR006171(TOPRIM)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR005737(DNA topoisomerase IV, subunit B, Gram-negative)|interpro:IPR018522|go:""GO:0003677""(DNA binding)|go:""GO:0003918""(""DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0006265""(DNA topological change)|go:""GO:0007059""(chromosome segregation)|go:""GO:0034335""(DNA negative supercoiling activity)|refseq:YP_002345736.1|refseq:WP_002212181.1|interpro:IPR036890|panther:PTHR45866(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606	rogid:KIv5q/TV/0ZL6T8o4DD+ZUm2jNM632	intact-crc:1D6333EC79F90904|rigid:2nXkl20h+/X4gtwHr3d5OiphfBs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01889	uniprotkb:Q7ARD3	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877365|imex:IM-13779-8494	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:1E1A260EE47E1940|rigid:P5PlvWkz7FFNkeRmIvNxSwxgauY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04439	uniprotkb:A0A2S9PFE9	intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155|ensembl:ENSP00000366005.5|ensembl:ENSP00000379873.1|ensembl:ENSP00000516612.1|ensembl:ENSP00000516614.1|ensembl:ENSP00000516616.1	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym)	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877372|imex:IM-13779-8495	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:179""|ensembl:ENSG00000206503.15(gene)|ensembl:ENST00000376809.10(transcript)|ensembl:ENST00000396634.5(transcript)|ensembl:ENST00000706901.1(transcript)|ensembl:ENST00000706903.1(transcript)|ensembl:ENST00000706905.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002419""(T cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002485""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0003723""(RNA binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0062061""(TAP complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2000568""(positive regulation of memory T cell activation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WJ5|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:7L1B|rcsb pdb:7L1C|rcsb pdb:7L1D|rcsb pdb:7MLE|rcsb pdb:7PHR|rcsb pdb:7QPD|rcsb pdb:7RK7|rcsb pdb:7RM4|rcsb pdb:7RRG|rcsb pdb:7STF|rcsb pdb:7UC5|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|rcsb pdb:8DVG|rcsb pdb:8RYM|rcsb pdb:8RYO|rcsb pdb:8RYP|rcsb pdb:8UDR|rcsb pdb:8VR9|rcsb pdb:8VRA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_001229687.1|refseq:NP_002107.3|ensembl:ENSP00000366005.5|ensembl:ENSP00000379873.1|ensembl:ENSP00000516612.1|ensembl:ENSP00000516614.1|ensembl:ENSP00000516616.1|panther:PTHR16675(orthology-group)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	intact-crc:3E44EC186B12C688|rigid:XbEUGx07iyLAXj2zPX6pLUjLz/E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YAM6	uniprotkb:P01889	intact:EBI-2844150|uniprotkb:Q7CFP2|uniprotkb:Q0W9V4	intact:EBI-1046513|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6	psi-mi:a0a5p8yam6_yerpe(display_long)|uniprotkb:malS(gene name)|psi-mi:malS(display_short)|uniprotkb:YPO4080(locus name)	psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877358|imex:IM-13779-8496	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014635(Alpha-amylase, MalS type)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209631.1|go:""GO:0004556""(alpha-amylase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0009313""(oligosaccharide catabolic process)|go:""GO:0030980""(alpha-glucan catabolic process)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348934.1|panther:PTHR10357(orthology-group)"	"ensembl:ENSG00000234745.14(gene)|ensembl:ENST00000412585.7(transcript)|ensembl:ENST00000696559.1(transcript)|ensembl:ENST00000696560.1(transcript)|ensembl:ENST00000696561.1(transcript)|ensembl:ENST00000696562.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002667""(regulation of T cell anergy)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016045""(detection of bacterium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032675""(regulation of interleukin-6 production)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0046977""(TAP binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P01889|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7RZD|rcsb pdb:7RZJ|rcsb pdb:7S79|rcsb pdb:7S7D|rcsb pdb:7S7E|rcsb pdb:7S7F|rcsb pdb:7S8A|rcsb pdb:7S8E|rcsb pdb:7S8F|rcsb pdb:8TUB|rcsb pdb:8TUH|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005505.2|efo:""Orphanet:117""|efo:""Orphanet:275798""|efo:""Orphanet:29207""|efo:""Orphanet:3287""|efo:""Orphanet:36426""|efo:""Orphanet:397""|panther:PTHR16675(orthology-group)|ensembl:ENSP00000399168.2|ensembl:ENSP00000512717.1|ensembl:ENSP00000512718.1|ensembl:ENSP00000512719.1|ensembl:ENSP00000512720.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qjQekYtSF56tT51Uzp+xShmXohk632	rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606	intact-crc:842CE46ACA3B06BB|rigid:2cQQs+rcEdUSN0z/0bDmu5P6agw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63104	uniprotkb:Q7ARN5	intact:EBI-347088|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6NUR9|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1	intact:EBI-2839967|uniprotkb:Q7CKL5|uniprotkb:Q74YZ9|uniprotkb:Q7ARK5|uniprotkb:Q7BTY3|uniprotkb:Q7BT06|uniprotkb:A0A1U8QKK8|uniprotkb:A0A3G5LBZ8|uniprotkb:A0A3G5L3F7	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:q7arn5_yerpe(display_long)|uniprotkb:ypmt1(gene name synonym)|uniprotkb:YPCD1.01(locus name)|uniprotkb:YPMT1.01(locus name)|uniprotkb:YPMT1.58c(locus name)|uniprotkb:YPPCP1.01(locus name)|uniprotkb:y1093(gene name)|psi-mi:y1093(display_short)|uniprotkb:YPO0031(locus name)|uniprotkb:YPO0171(locus name)|uniprotkb:YPO0249(locus name)|uniprotkb:YPO0386(locus name)|uniprotkb:YPO0528(locus name)|uniprotkb:YPO0567(locus name)|uniprotkb:YPO0637(locus name)|uniprotkb:YPO0780(locus name)|uniprotkb:YPO0826(locus name)|uniprotkb:YPO0924(locus name)|uniprotkb:YPO1013(locus name)|uniprotkb:YPO1086(locus name)|uniprotkb:YPO1132(locus name)|uniprotkb:YPO1338(locus name)|uniprotkb:YPO1427(locus name)|uniprotkb:YPO1520(locus name)|uniprotkb:YPO1623(locus name)|uniprotkb:YPO1692(locus name)|uniprotkb:YPO1729(locus name)|uniprotkb:YPO1750(locus name)|uniprotkb:YPO1900(locus name)|uniprotkb:YPO2026(locus name)|uniprotkb:YPO2085(locus name)|uniprotkb:YPO2178(locus name)|uniprotkb:YPO2365(locus name)|uniprotkb:YPO2396(locus name)|uniprotkb:YPO2516(locus name)|uniprotkb:YPO2643(locus name)|uniprotkb:YPO2721(locus name)|uniprotkb:YPO2808(locus name)|uniprotkb:YPO2932(locus name)|uniprotkb:YPO3209(locus name)|uniprotkb:YPO3251(locus name)|uniprotkb:YPO3282(locus name)|uniprotkb:YPO3434(locus name)|uniprotkb:YPO3542(locus name)|uniprotkb:YPO3591(locus name)|uniprotkb:YPO3701(locus name)|uniprotkb:YPO3756(locus name)|uniprotkb:YPO3774(locus name)|uniprotkb:YPO4010(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877407|imex:IM-13779-8497	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164924.18(gene)|ensembl:ENST00000353245.7(transcript)|ensembl:ENST00000395951.7(transcript)|ensembl:ENST00000395953.6(transcript)|ensembl:ENST00000395956.7(transcript)|ensembl:ENST00000395957.6(transcript)|ensembl:ENST00000395958.6(transcript)|ensembl:ENST00000419477.6(transcript)|ensembl:ENST00000457309.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001525""(angiogenesis)|go:""GO:0003016""(respiratory system process)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008039""(synaptic target recognition)|go:""GO:0008104""(protein localization)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030324""(lung development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031982""(vesicle)|go:""GO:0035148""(tube formation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0072562""(blood microparticle)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090168""(Golgi reassembly)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63104|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5J31|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|rcsb pdb:7MFD|rcsb pdb:7MFE|rcsb pdb:7MFF|rcsb pdb:7Q16|rcsb pdb:7ZIT|rcsb pdb:8A9G|rcsb pdb:8AH2|rcsb pdb:8QDV|rcsb pdb:8WE2|rcsb pdb:8WF6|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|efo:""Orphanet:178469""|panther:PTHR18860(orthology-group)|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1|ensembl:ENST00000522542.5|ensembl:ENSP00000430072.1"	"refseq:YP_002348636.1|refseq:YP_002348652.1|refseq:YP_002348877.1|interpro:IPR017894|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:NP_395138.1|refseq:NP_395227.1|refseq:NP_395336.1|refseq:NP_395402.1|refseq:NP_857638.1|refseq:NP_857716.1|refseq:NP_857780.1|refseq:YP_094025.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR036397|refseq:WP_000255944.1|refseq:YP_006960969.1|go:""GO:0000150""(DNA strand exchange activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0015074""(DNA integration)|go:""GO:0032196""(transposition)|interpro:IPR006120(Resolvase, helix-turn-helix region)|refseq:YP_002345127.1|refseq:YP_002345256.1|refseq:YP_002345330.1|refseq:YP_002345463.1|refseq:YP_002345601.1|refseq:YP_002345638.1|refseq:YP_002345704.1|refseq:YP_002345836.1|refseq:YP_002345880.1|refseq:YP_002345972.1|refseq:YP_002346056.1|refseq:YP_002346129.1|refseq:YP_002346174.1|refseq:YP_002346362.1|refseq:YP_002346450.1|refseq:YP_002346536.1|refseq:YP_002346634.1|refseq:YP_002346730.1|refseq:YP_002346750.1|refseq:YP_002346890.1|refseq:YP_002347010.1|refseq:YP_002347066.1|refseq:YP_002347152.1|refseq:YP_002347332.1|refseq:YP_002347362.1|refseq:YP_002347480.1|refseq:YP_002347596.1|refseq:YP_002347668.1|refseq:YP_002347749.1|refseq:YP_002347862.1|refseq:YP_002348112.1|refseq:YP_002348152.1|refseq:YP_002348181.1|refseq:YP_002348326.1|refseq:YP_002348430.1|refseq:YP_002348476.1|refseq:YP_002346695.1|refseq:YP_002348583.1|panther:PTHR35004(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:gYoFpz6mpcJ4NYVEafsAkK14EIE632	intact-crc:C7F34899EA5C35B4|rigid:BpOugdEARi4weIcAzX6iifbeksQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63104	uniprotkb:Q8ZG99	intact:EBI-347088|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6NUR9|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1	intact:EBI-2842803|uniprotkb:Q0WH10	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:mukb_yerpe(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:YPO1405(locus name)|uniprotkb:y2765(locus name)|uniprotkb:YP_1188(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877414|imex:IM-13779-8501	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164924.18(gene)|ensembl:ENST00000353245.7(transcript)|ensembl:ENST00000395951.7(transcript)|ensembl:ENST00000395953.6(transcript)|ensembl:ENST00000395956.7(transcript)|ensembl:ENST00000395957.6(transcript)|ensembl:ENST00000395958.6(transcript)|ensembl:ENST00000419477.6(transcript)|ensembl:ENST00000457309.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001525""(angiogenesis)|go:""GO:0003016""(respiratory system process)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008039""(synaptic target recognition)|go:""GO:0008104""(protein localization)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030324""(lung development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031982""(vesicle)|go:""GO:0035148""(tube formation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0072562""(blood microparticle)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090168""(Golgi reassembly)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63104|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5J31|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|rcsb pdb:7MFD|rcsb pdb:7MFE|rcsb pdb:7MFF|rcsb pdb:7Q16|rcsb pdb:7ZIT|rcsb pdb:8A9G|rcsb pdb:8AH2|rcsb pdb:8QDV|rcsb pdb:8WE2|rcsb pdb:8WF6|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|efo:""Orphanet:178469""|panther:PTHR18860(orthology-group)|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1|ensembl:ENST00000522542.5|ensembl:ENSP00000430072.1"	"interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR027417|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0009295""(nucleoid)|go:""GO:0030261""(chromosome condensation)|go:""GO:0051301""(cell division)|refseq:WP_002211308.1|interpro:IPR032520|interpro:IPR042501|refseq:YP_002346428.1|interpro:IPR050308|panther:PTHR42963(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:S3C/l5VT7GRTCJdJZg8Vl6UtJlU632	intact-crc:60E1026B36DB51A8|rigid:p6a5B+1CKkN09zU2gFYlR1b9Ksc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01892	uniprotkb:Q8CWG4	intact:EBI-2839473|uniprotkb:Q9TPY0|uniprotkb:Q29680|uniprotkb:Q29899|uniprotkb:P06338|uniprotkb:P30445|uniprotkb:Q95352|uniprotkb:Q9TQI3|uniprotkb:Q95380|uniprotkb:P30444|uniprotkb:Q9TPX8|uniprotkb:O19619|uniprotkb:P30446|uniprotkb:Q9TQH5|uniprotkb:P10313|uniprotkb:Q9TPX9|uniprotkb:P30514|uniprotkb:Q29837	intact:EBI-2856530|uniprotkb:Q74QZ9	psi-mi:1a02_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A*02(gene name synonym)	psi-mi:q8cwg4_yerpe(display_long)|uniprotkb:glpD(gene name)|psi-mi:glpD(display_short)|uniprotkb:YP_3299(locus name)|uniprotkb:y3891(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877386|imex:IM-13779-8500	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:4MNQ|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5HYJ|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5HHM|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E6I|rcsb pdb:5IRO|rcsb pdb:6D7G|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0070971""(endoplasmic reticulum exit site)|rcsb pdb:4EMZ|rcsb pdb:4EN2|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|go:""GO:0031901""(early endosome membrane)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0000139""(Golgi membrane)|go:""GO:0071556""(obsolete integral component of lumenal side of endoplasmic reticulum membrane)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0050690""|go:""GO:0060337""(type I interferon-mediated signaling pathway)|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0009986""(cell surface)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0046977""(TAP binding)|go:""GO:2000568""(positive regulation of memory T cell activation)|rcsb pdb:3QFD|rcsb pdb:4K7F|go:""GO:0002479""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:""GO:0002480""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:""GO:0030670""(phagocytic vesicle membrane)|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:5NMG|rcsb pdb:5NHT|rcsb pdb:5NQK|rcsb pdb:4WUU|rcsb pdb:4E5X|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:4I4W|rcsb pdb:5EOT|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:3TO2|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4EUP|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|rcsb pdb:4FTV|rcsb pdb:5E9D|rcsb pdb:5C07|rcsb pdb:5C08|go:""GO:0005102""(signaling receptor binding)|go:""GO:0002474""(antigen processing and presentation of peptide antigen via MHC class I)|go:""GO:0005886""(plasma membrane)|go:""GO:0050776""(regulation of immune response)|ensembl:ENST00000457879|ensembl:ENST00000547271|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:""GO:0042608""(T cell receptor binding)|rcsb pdb:4L3E|ensembl:ENSG00000235657|ensembl:ENSP00000403575|ensembl:ENSP00000447962|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4OV5|rcsb pdb:4UQ3|ensembl:ENSG00000227715|ensembl:ENSP00000448077|ensembl:ENST00000547522|rcsb pdb:5SWQ|rcsb pdb:4WJ5|go:""GO:0003723""(RNA binding)|go:""GO:0055038""(recycling endosome membrane)|rcsb pdb:5E00|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|go:""GO:0051290""(protein heterotetramerization)|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5N1Y|go:""GO:0002250""(adaptive immune response)|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:5ENW|reactome:R-HSA-8866654|rcsb pdb:5JZI|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5TEZ|rcsb pdb:5WSH|mint:P01892|rcsb pdb:5N6B|rcsb pdb:5W1W|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|go:""GO:0002485""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0062061""(TAP complex binding)|rcsb pdb:6G3J"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR031656|go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0006072""(glycerol-3-phosphate metabolic process)|go:""GO:0009331""(""glycerol-3-phosphate dehydrogenase (FAD) complex"")|interpro:IPR038299|interpro:IPR036188"	"psi-mi:""MI:0469""(intact)"	"no-uniprot-update:Deprecated HLA-A AC, merged into a different UniProt canonical but we have mutation features in variable positions.|comment:""\""Allele =A*02:01:01:01\""""|comment:""\""Allele =A*02:01:01:01 according to IPD-IMGT/HLA database\"""""	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oTL0BWZeACoxMc++WgT0XDz+sNg9606	rogid:R9I22ZXVmXiKYYz/+NgwNjlHCb0632	intact-crc:5302DB6704FF42DE|rigid:m2ev/LTPDnMghQt00aUZgGzjcgU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63104	uniprotkb:Q0WHB9	intact:EBI-347088|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6NUR9|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1	intact:EBI-2865474|uniprotkb:Q74VK6|uniprotkb:Q7CHE5|uniprotkb:A0A0H2W3B9|uniprotkb:A0A380PMW6	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:q0whb9_yerpe(display_long)|uniprotkb:YPO1293(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877400|imex:IM-13779-8499	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164924.18(gene)|ensembl:ENST00000353245.7(transcript)|ensembl:ENST00000395951.7(transcript)|ensembl:ENST00000395953.6(transcript)|ensembl:ENST00000395956.7(transcript)|ensembl:ENST00000395957.6(transcript)|ensembl:ENST00000395958.6(transcript)|ensembl:ENST00000419477.6(transcript)|ensembl:ENST00000457309.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001525""(angiogenesis)|go:""GO:0003016""(respiratory system process)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008039""(synaptic target recognition)|go:""GO:0008104""(protein localization)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030324""(lung development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031982""(vesicle)|go:""GO:0035148""(tube formation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0072562""(blood microparticle)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090168""(Golgi reassembly)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63104|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5J31|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|rcsb pdb:7MFD|rcsb pdb:7MFE|rcsb pdb:7MFF|rcsb pdb:7Q16|rcsb pdb:7ZIT|rcsb pdb:8A9G|rcsb pdb:8AH2|rcsb pdb:8QDV|rcsb pdb:8WE2|rcsb pdb:8WF6|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|efo:""Orphanet:178469""|panther:PTHR18860(orthology-group)|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1|ensembl:ENST00000522542.5|ensembl:ENSP00000430072.1"	"interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR025997|interpro:IPR028082|refseq:WP_002208804.1|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030313""(cell envelope)|refseq:YP_002346319.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:005N4coCeNHtTXwgUb8LFuJEQkQ632	intact-crc:09A018BDBECBA009|rigid:JqPWKyC7E1ONiUCNPruiPlo1Sm8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PIA6	uniprotkb:P01892	intact:EBI-2842908|uniprotkb:Q74VK3|uniprotkb:Q7CHE2|uniprotkb:A0A5P8YDR0|uniprotkb:A0A0H2W4I9	intact:EBI-2839473|uniprotkb:Q9TPY0|uniprotkb:Q29680|uniprotkb:Q29899|uniprotkb:P06338|uniprotkb:P30445|uniprotkb:Q95352|uniprotkb:Q9TQI3|uniprotkb:Q95380|uniprotkb:P30444|uniprotkb:Q9TPX8|uniprotkb:O19619|uniprotkb:P30446|uniprotkb:Q9TQH5|uniprotkb:P10313|uniprotkb:Q9TPX9|uniprotkb:P30514|uniprotkb:Q29837	psi-mi:a0a2s9pia6_yerpe(display_long)|uniprotkb:YPO1289(locus name)	psi-mi:1a02_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A*02(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877393|imex:IM-13779-8498	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011234(Fumarylacetoacetase, C-terminal-related)|refseq:WP_002208808.1|go:""GO:0003824""(catalytic activity)|go:""GO:0044281""(small molecule metabolic process)|interpro:IPR036663|refseq:YP_002346315.1|interpro:IPR051121"	"rcsb pdb:4MNQ|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5HYJ|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5HHM|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E6I|rcsb pdb:5IRO|rcsb pdb:6D7G|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0070971""(endoplasmic reticulum exit site)|rcsb pdb:4EMZ|rcsb pdb:4EN2|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|go:""GO:0031901""(early endosome membrane)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0000139""(Golgi membrane)|go:""GO:0071556""(obsolete integral component of lumenal side of endoplasmic reticulum membrane)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0050690""|go:""GO:0060337""(type I interferon-mediated signaling pathway)|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0009986""(cell surface)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0046977""(TAP binding)|go:""GO:2000568""(positive regulation of memory T cell activation)|rcsb pdb:3QFD|rcsb pdb:4K7F|go:""GO:0002479""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:""GO:0002480""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:""GO:0030670""(phagocytic vesicle membrane)|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:5NMG|rcsb pdb:5NHT|rcsb pdb:5NQK|rcsb pdb:4WUU|rcsb pdb:4E5X|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:4I4W|rcsb pdb:5EOT|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:3TO2|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4EUP|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|rcsb pdb:4FTV|rcsb pdb:5E9D|rcsb pdb:5C07|rcsb pdb:5C08|go:""GO:0005102""(signaling receptor binding)|go:""GO:0002474""(antigen processing and presentation of peptide antigen via MHC class I)|go:""GO:0005886""(plasma membrane)|go:""GO:0050776""(regulation of immune response)|ensembl:ENST00000457879|ensembl:ENST00000547271|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:""GO:0042608""(T cell receptor binding)|rcsb pdb:4L3E|ensembl:ENSG00000235657|ensembl:ENSP00000403575|ensembl:ENSP00000447962|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4OV5|rcsb pdb:4UQ3|ensembl:ENSG00000227715|ensembl:ENSP00000448077|ensembl:ENST00000547522|rcsb pdb:5SWQ|rcsb pdb:4WJ5|go:""GO:0003723""(RNA binding)|go:""GO:0055038""(recycling endosome membrane)|rcsb pdb:5E00|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|go:""GO:0051290""(protein heterotetramerization)|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5N1Y|go:""GO:0002250""(adaptive immune response)|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:5ENW|reactome:R-HSA-8866654|rcsb pdb:5JZI|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5TEZ|rcsb pdb:5WSH|mint:P01892|rcsb pdb:5N6B|rcsb pdb:5W1W|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|go:""GO:0002485""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0062061""(TAP complex binding)|rcsb pdb:6G3J"	"psi-mi:""MI:0469""(intact)"	-	"no-uniprot-update:Deprecated HLA-A AC, merged into a different UniProt canonical but we have mutation features in variable positions.|comment:""\""Allele =A*02:01:01:01\""""|comment:""\""Allele =A*02:01:01:01 according to IPD-IMGT/HLA database\"""""	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3/IrNkmiHMcBViQNlB32br606NM632	rogid:oTL0BWZeACoxMc++WgT0XDz+sNg9606	intact-crc:AD2A65245E86BD82|rigid:WO5S9Zp+w9KN8YmJJBx7CgX2IMw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62258	uniprotkb:Q8CZY0	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335.8|ensembl:ENSP00000487356.1	intact:EBI-2843763	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:q8czy0_yerpe(display_long)|uniprotkb:y3182(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877435|imex:IM-13779-8505	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:213711""|efo:""Orphanet:217385""|efo:""Orphanet:261257""|efo:""Orphanet:457246""|efo:""Orphanet:531""|dip:DIP-36676N|ensembl:ENSG00000108953.17(gene)|ensembl:ENSG00000274474.3(gene)|ensembl:ENST00000264335.13(transcript)|ensembl:ENST00000627231.2(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001764""(neuron migration)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003064""(regulation of heart rate by hormone)|go:""GO:0003723""(RNA binding)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008104""(protein localization)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0060306""(regulation of membrane repolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|go:""GO:1905913""(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|rcsb pdb:7V9B|rcsb pdb:8DGM|rcsb pdb:8DGN|rcsb pdb:8DGP|rcsb pdb:8DP5|rcsb pdb:8Q1S|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_006752.1|panther:PTHR18860(orthology-group)|ensembl:ENSP00000264335.8|ensembl:ENST00000571732.5|ensembl:ENSP00000461762.1|ensembl:ENST00000616643.3|ensembl:ENSP00000481059.2|ensembl:ENSP00000487356.1"	"interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR041954|interpro:IPR050612"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/21	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:Y5d3heMPjpe23bUutQ9OKW+v73g632	intact-crc:3F12893416F80509|rigid:S4bfuJbXgVCzN+W48etKrdwSXZg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIH1	uniprotkb:P63104	intact:EBI-2841326|uniprotkb:Q0WJD6	intact:EBI-347088|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6NUR9|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1	psi-mi:leud_yerpe(display_long)|uniprotkb:leuD(gene name)|psi-mi:leuD(display_short)|uniprotkb:Alpha-IPM isomerase(gene name synonym)|uniprotkb:Isopropylmalate isomerase(gene name synonym)|uniprotkb:YPO0530(locus name)|uniprotkb:y3648(locus name)|uniprotkb:YP_3652(locus name)	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877421|imex:IM-13779-8504	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004431(3-isopropylmalate dehydratase, small subunit region)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|go:""GO:0003861""(3-isopropylmalate dehydratase activity)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009316""(3-isopropylmalate dehydratase complex)|refseq:WP_002210456.1|refseq:YP_002345602.1|interpro:IPR033940|interpro:IPR050075|panther:PTHR43345(orthology-group)"	"ensembl:ENSG00000164924.18(gene)|ensembl:ENST00000353245.7(transcript)|ensembl:ENST00000395951.7(transcript)|ensembl:ENST00000395953.6(transcript)|ensembl:ENST00000395956.7(transcript)|ensembl:ENST00000395957.6(transcript)|ensembl:ENST00000395958.6(transcript)|ensembl:ENST00000419477.6(transcript)|ensembl:ENST00000457309.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001525""(angiogenesis)|go:""GO:0003016""(respiratory system process)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008039""(synaptic target recognition)|go:""GO:0008104""(protein localization)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030324""(lung development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031982""(vesicle)|go:""GO:0035148""(tube formation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0072562""(blood microparticle)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090168""(Golgi reassembly)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63104|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5J31|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|rcsb pdb:7MFD|rcsb pdb:7MFE|rcsb pdb:7MFF|rcsb pdb:7Q16|rcsb pdb:7ZIT|rcsb pdb:8A9G|rcsb pdb:8AH2|rcsb pdb:8QDV|rcsb pdb:8WE2|rcsb pdb:8WF6|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|efo:""Orphanet:178469""|panther:PTHR18860(orthology-group)|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1|ensembl:ENST00000522542.5|ensembl:ENSP00000430072.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:lF0EK380WhlR7ondVqFIwVAnDFQ632	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	intact-crc:DAE4AC6B342E0598|rigid:w1qI/uMkXKjZZjEPjVRd7WZYThA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q04917	uniprotkb:A0A5P8YC69	intact:EBI-306940|intact:EBI-11759595|ensembl:ENSP00000248975.5|intact:EBI-21351354	intact:EBI-2846502|uniprotkb:Q74XS9|uniprotkb:A0A0H2W2P5|uniprotkb:Q7CKD1|uniprotkb:A0A384LA02	psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym)	psi-mi:a0a5p8yc69_yerpe(display_long)|uniprotkb:YPO3378(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877428|imex:IM-13779-8502	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003396.1|ensembl:ENSG00000128245.15(gene)|ensembl:ENST00000248975.6(transcript)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0003779""(actin binding)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006713""(glucocorticoid catabolic process)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0014704""(intercalated disc)|go:""GO:0017080""(sodium channel regulator activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0035259""(nuclear glucocorticoid receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042921""(nuclear receptor-mediated glucocorticoid signaling pathway)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045664""(regulation of neuron differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048167""(regulation of synaptic plasticity)|go:""GO:0050774""(negative regulation of dendrite morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0086010""(membrane depolarization during action potential)|go:""GO:0098793""(presynapse)|go:""GO:0099171""(presynaptic modulation of chemical synaptic transmission)|go:""GO:0150048""(cerebellar granule cell to Purkinje cell synapse)|go:""GO:2000649""(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|rcsb pdb:7NMZ|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9735871|reactome:R-HSA-9755779|dip:DIP-27566N|ensembl:ENSP00000248975.5|panther:PTHR18860(orthology-group)"	"interpro:IPR004518(NTP pyrophosphohydrolase MazG, putative catalytic core)|interpro:IPR011551(NTP pyrophosphohydrolase MazG, bacterial)|refseq:WP_002209374.1|go:""GO:0006203""(dGTP catabolic process)|go:""GO:0046047""(TTP catabolic process)|go:""GO:0046052""(UTP catabolic process)|go:""GO:0046061""(dATP catabolic process)|go:""GO:0046076""(dTTP catabolic process)|go:""GO:0046081""(dUTP catabolic process)|go:""GO:0047429""(nucleoside triphosphate diphosphatase activity)|interpro:IPR048011|interpro:IPR048015|refseq:YP_002348270.1|panther:PTHR30522(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606	rogid:tBYkUwn2dX204c5lW1AdxLvjQiY632	intact-crc:B90075ADF4E171BE|rigid:XDKbGO9Ypik+kyha+l6ImLqlLuo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62258	uniprotkb:Q8ZG99	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335.8|ensembl:ENSP00000487356.1	intact:EBI-2842803|uniprotkb:Q0WH10	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:mukb_yerpe(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:YPO1405(locus name)|uniprotkb:y2765(locus name)|uniprotkb:YP_1188(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2877442|imex:IM-13779-8503	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:213711""|efo:""Orphanet:217385""|efo:""Orphanet:261257""|efo:""Orphanet:457246""|efo:""Orphanet:531""|dip:DIP-36676N|ensembl:ENSG00000108953.17(gene)|ensembl:ENSG00000274474.3(gene)|ensembl:ENST00000264335.13(transcript)|ensembl:ENST00000627231.2(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001764""(neuron migration)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003064""(regulation of heart rate by hormone)|go:""GO:0003723""(RNA binding)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008104""(protein localization)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0060306""(regulation of membrane repolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0086013""(membrane repolarization during cardiac muscle cell action potential)|go:""GO:0086091""(regulation of heart rate by cardiac conduction)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901379""(regulation of potassium ion transmembrane transport)|go:""GO:1905913""(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|rcsb pdb:7V9B|rcsb pdb:8DGM|rcsb pdb:8DGN|rcsb pdb:8DGP|rcsb pdb:8DP5|rcsb pdb:8Q1S|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_006752.1|panther:PTHR18860(orthology-group)|ensembl:ENSP00000264335.8|ensembl:ENST00000571732.5|ensembl:ENSP00000461762.1|ensembl:ENST00000616643.3|ensembl:ENSP00000481059.2|ensembl:ENSP00000487356.1"	"interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR027417|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0009295""(nucleoid)|go:""GO:0030261""(chromosome condensation)|go:""GO:0051301""(cell division)|refseq:WP_002211308.1|interpro:IPR032520|interpro:IPR042501|refseq:YP_002346428.1|interpro:IPR050308|panther:PTHR42963(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/21	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:S3C/l5VT7GRTCJdJZg8Vl6UtJlU632	intact-crc:959D45DD14543865|rigid:ucm/2rDDaUr1EKQToR8CIGyZVZg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YCL9	uniprotkb:Q13492	intact:EBI-2854251|uniprotkb:Q74QH5|uniprotkb:A0A0H2W7Z7|uniprotkb:Q7CGR8|uniprotkb:A0A384LLI6	intact:EBI-2803688|uniprotkb:Q86XZ9|uniprotkb:O60700|uniprotkb:Q6GMQ6|uniprotkb:B4DTM3|uniprotkb:E9PN05|uniprotkb:F8VPG7|uniprotkb:Q4LE54|ensembl:ENSP00000377015.3|intact:EBI-28967113	psi-mi:a0a5p8ycl9_yerpe(display_long)|uniprotkb:proC(gene name)|psi-mi:proC(display_short)|uniprotkb:PCA reductase(gene name synonym)|uniprotkb:YPO0942(locus name)	psi-mi:pical_human(display_long)|uniprotkb:CALM(gene name synonym)|uniprotkb:Clathrin assembly lymphoid myeloid leukemia protein(gene name synonym)|uniprotkb:PICALM(gene name)|psi-mi:PICALM(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861305|imex:IM-13779-6621	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR028939|interpro:IPR029036|refseq:WP_002209983.1|go:""GO:0004735""(pyrroline-5-carboxylate reductase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR036291|interpro:IPR053790|refseq:YP_002345989.1|panther:PTHR11645(orthology-group)"	"ensembl:ENSG00000073921.18(gene)|ensembl:ENST00000393346.8(transcript)|go:""GO:0000149""(SNARE binding)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0005545""(1-phosphatidylinositol binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006897""(endocytosis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006900""(vesicle budding from membrane)|go:""GO:0007409""(axonogenesis)|go:""GO:0007611""(learning or memory)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0009986""(cell surface)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016185""(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:""GO:0016188""(synaptic vesicle maturation)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030132""(clathrin coat of coated pit)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030276""(clathrin binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031623""(receptor internalization)|go:""GO:0031982""(vesicle)|go:""GO:0032050""(clathrin heavy chain binding)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0045334""(clathrin-coated endocytic vesicle)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0048156""(tau protein binding)|go:""GO:0048261""(negative regulation of receptor-mediated endocytosis)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070381""(endosome to plasma membrane transport vesicle)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097418""(neurofibrillary tangle)|go:""GO:0097494""(regulation of vesicle size)|go:""GO:0097753""(membrane bending)|go:""GO:0098894""(extrinsic component of presynaptic endocytic zone membrane)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|go:""GO:1902991""(regulation of amyloid precursor protein catabolic process)|go:""GO:1902993""(positive regulation of amyloid precursor protein catabolic process)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:2000009""(negative regulation of protein localization to cell surface)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR045192|mint:Q13492|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9696264|refseq:NP_001008660.1|refseq:NP_001193875.1|refseq:NP_001193876.1|refseq:NP_009097.2|refseq:XP_005274388.1|efo:""Orphanet:99861""|panther:PTHR22951(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:paSjAu5D9ZaxK08iRvRWzJT6u+4632	rogid:UIZhYyYqmBCyN4xwPCl9PeCdK8Q9606	intact-crc:697C160FC1B1AA72|rigid:4GiFGHfMtrRU3NmZubBvxUPQnmE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WIJ4	uniprotkb:Q8WXW3	intact:EBI-2861319|uniprotkb:Q74QE4|uniprotkb:Q7CGW6|uniprotkb:A0A5P8YE89|uniprotkb:A0A0H2W9C5	intact:EBI-2558770|uniprotkb:Q96SF4|uniprotkb:Q86V07|uniprotkb:Q6U9V2|uniprotkb:O95664|uniprotkb:Q6UG50|ensembl:ENSP00000317144.6	psi-mi:q0wij4_yerpe(display_long)|uniprotkb:YPO0843(locus name)	psi-mi:pibf1_human(display_long)|uniprotkb:PIBF1(gene name)|psi-mi:PIBF1(display_short)|uniprotkb:C13orf24(gene name synonym)|uniprotkb:PIBF(gene name synonym)|uniprotkb:Centrosomal protein of 90 kDa(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861323|imex:IM-13779-6620	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR016624(Uncharacterised conserved protein UCP014753)|refseq:WP_002209887.1|interpro:IPR049349|refseq:YP_002345894.1	"dip:DIP-56669N|efo:""Orphanet:475""|ensembl:ENSG00000083535.16(gene)|ensembl:ENST00000326291.11(transcript)|go:""GO:0002376""(immune system process)|go:""GO:0005136""(interleukin-4 receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0031393""(negative regulation of prostaglandin biosynthetic process)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032815""(negative regulation of natural killer cell activation)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042531""(positive regulation of tyrosine phosphorylation of STAT protein)|go:""GO:0042532""(negative regulation of tyrosine phosphorylation of STAT protein)|go:""GO:0042976""(activation of Janus kinase activity)|go:""GO:0060271""(cilium assembly)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR026205|mint:Q8WXW3|refseq:NP_006337.2|panther:PTHR18950(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TrmUttfAizdLZfz33Sej82hexrQ632	rogid:830BcMpvq9x1Dg1ybOjNg/y4BH09606	intact-crc:D7118D7C3E172DBC|rigid:URAccCGm/MajuMR3qrqSxJL2U2k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKJ0	uniprotkb:Q9X6B0	intact:EBI-347958|ensembl:ENSP00000391748.1|ensembl:ENSP00000477365.1|uniprotkb:Q69YF9|uniprotkb:Q9HBS0	intact:EBI-2844324|intact:EBI-2856296|uniprotkb:Q0WBX3	psi-mi:pilrb_human(display_long)|uniprotkb:Cell surface receptor FDFACT(gene name synonym)|uniprotkb:Activating receptor PILR-beta(gene name synonym)|uniprotkb:PILRB(gene name)|psi-mi:PILRB(display_short)|uniprotkb:FDFACT(gene name synonym)|uniprotkb:PP1551(orf name)	psi-mi:katg_yerpe(display_long)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)|uniprotkb:katY(gene name synonym)|uniprotkb:Antigen 5(gene name synonym)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:YPO3319(locus name)|uniprotkb:y0870(locus name)|uniprotkb:YP_0367(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861291|imex:IM-13779-6622	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_839956.1|ensembl:ENSG00000121716.21(gene)|ensembl:ENST00000452089.5(transcript)|ensembl:ENST00000609309.3(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007171""(activation of transmembrane receptor protein tyrosine kinase activity)|go:""GO:0042288""(MHC class I protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR051694|rcsb pdb:4NFC|rcsb pdb:4NFD|reactome:R-HSA-198933"	"interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|go:""GO:0004096""(catalase activity)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|refseq:WP_002209433.1|refseq:YP_002348215.1|panther:PTHR30555(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qYRLa9Orh2rxX2iOh6jsqVPgjGg9606	rogid:RBebELhpxkVGfQv9Ix9rW4jzmpE632	intact-crc:F9FC2FC67A8A8832|rigid:7V8vVnXb7cnYPoxyoYCQIDm9zE4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99570	uniprotkb:A0A7Y8RCW6	intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205.3	intact:EBI-2845056|uniprotkb:Q7CKM5|uniprotkb:A0A5P8YBL8|uniprotkb:Q0WJU7	psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym)	psi-mi:a0a7y8rcw6_yerpe(display_long)|uniprotkb:YPO0363(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861351|imex:IM-13779-6627	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055417.1|ensembl:ENSG00000196455.8(gene)|ensembl:ENST00000356763.8(transcript)|go:""GO:0000425""(pexophagy)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005770""(late endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0005829""(cytosol)|go:""GO:0005930""(axoneme)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032801""(receptor catabolic process)|go:""GO:0034271""(phosphatidylinositol 3-kinase complex, class III, type I)|go:""GO:0034272""(phosphatidylinositol 3-kinase complex, class III, type II)|go:""GO:0035032""(phosphatidylinositol 3-kinase complex, class III)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036092""(phosphatidylinositol-3-phosphate biosynthetic process)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045324""(late endosome to vacuole transport)|go:""GO:0071561""(nucleus-vacuole junction)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|interpro:IPR045162|interpro:IPR055231|mint:Q99570|rcsb pdb:7BL1|rcsb pdb:8SOR|rcsb pdb:9C82|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|reactome:R-HSA-9705671|reactome:R-HSA-983170|dip:DIP-42310N|panther:PTHR17583(orthology-group)"	"interpro:IPR024393|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR011066(Mechanosensitive ion channel MscS, C-terminal)|interpro:IPR006685(Mechanosensitive ion channel MscS)|interpro:IPR011014(Mechanosensitive ion channel MscS, transmembrane-2)|interpro:IPR006686(Mechanosensitive ion channel MscS, conserved site)|interpro:IPR025692|go:""GO:0005886""(plasma membrane)|go:""GO:0008381""(mechanosensitive monoatomic ion channel activity)|interpro:IPR049142|interpro:IPR049278|interpro:IPR023408|refseq:YP_002345441.1|interpro:IPR052702"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/28	rogid:CjToF5FvjyANBQtA1wuWQxC82889606	rogid:z6l0v0GxSQqbhV/esC/hffWqLG8632	intact-crc:E5D66B917CB0C164|rigid:6J3UUt5/bRcwEzVQInBhTq9AeQc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6X2	uniprotkb:P42713	intact:EBI-2803703|uniprotkb:Q9UFI3|ensembl:ENSP00000376765.2|intact:EBI-28970301	intact:EBI-2855318	psi-mi:pias3_human(display_long)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:PIAS3(gene name)|psi-mi:PIAS3(display_short)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym)	psi-mi:yscq_yerpe(display_long)|uniprotkb:yscQ(gene name)|psi-mi:yscQ(display_short)|uniprotkb:YPCD1.43(locus name)|uniprotkb:y5035(locus name)|uniprotkb:y0038(locus name)|uniprotkb:YP_pCD40(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861330|imex:IM-13779-6623	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006090.2|ensembl:ENSG00000131788.16(gene)|ensembl:ENST00000393045.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0016607""(nuclear speck)|go:""GO:0016925""(protein sumoylation)|go:""GO:0019789""(SUMO transferase activity)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0033235""(positive regulation of protein sumoylation)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0099524""(postsynaptic cytosol)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR036361|interpro:IPR038654|mint:Q9Y6X2|rcsb pdb:4MVT|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|dip:DIP-5969N|ensembl:ENSP00000376765.2|panther:PTHR10782(orthology-group)"	"refseq:NP_395177.1|refseq:NP_857739.1|refseq:NP_857934.1|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|interpro:IPR003283(Type III secretion system outer membrane O protein)|interpro:IPR013385(Type III secretion system apparatus protein YscQ/HrcQ)|refseq:WP_002212948.1|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0071978""(bacterial-type flagellum-dependent swarming motility)|interpro:IPR036429|panther:PTHR30034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uAxtGVgFcpm5yJL1rul8vVciHZA9606	rogid:6QCEVIThofNCQV+S/cN32USA1WE632	intact-crc:FCE521BF77CAAC76|rigid:/na5SJPcND5rtx6FYp7xREE65FE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N3S3	uniprotkb:A0A0H2W0W1	intact:EBI-2840195|uniprotkb:A0JP04|uniprotkb:Q9H099|uniprotkb:A0JP05|uniprotkb:A4D1C2|uniprotkb:E9PEE3|uniprotkb:G5E9H7|uniprotkb:Q6NW35|uniprotkb:Q8TBW4|uniprotkb:B3KQZ2|ensembl:ENSP00000248550.7|ensembl:ENSP00000400958.3|intact:EBI-28985369	intact:EBI-2843417|uniprotkb:Q74X81|uniprotkb:Q0WBD9|uniprotkb:Q7CKJ7|uniprotkb:A0A2U2H033|uniprotkb:A0A384KHX8	psi-mi:phtf2_human(display_long)|uniprotkb:PHTF2(gene name)|psi-mi:PHTF2(display_short)	psi-mi:a0a0h2w0w1_yerpe(display_long)|uniprotkb:YPO3510(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861370|imex:IM-13779-6625	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001120831.1|refseq:NP_001120832.1|refseq:NP_001120829.1|refseq:NP_001120830.1|refseq:NP_065165.3|refseq:XP_005250565.1|refseq:XP_005250566.1|ensembl:ENSG00000006576.17(gene)|ensembl:ENST00000248550.7(transcript)|ensembl:ENST00000416283.6(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0016020""(membrane)|interpro:IPR021980|interpro:IPR039775|panther:PTHR12680(orthology-group)"	"interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|go:""GO:0016020""(membrane)|refseq:WP_002210180.1|refseq:YP_002348399.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:drQQTp4F6hNVAdNF5MdXoLgpXsE9606	rogid:WAAPN9EE9NNNraWqy5ZHHVoV/5k632	intact-crc:BA27D32897D2A2CE|rigid:Eh7f178hlZWviIa+DaIFz9Mef4k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0R4	uniprotkb:Q6NYC8	intact:EBI-2861358|uniprotkb:Q74T93	intact:EBI-2557469|uniprotkb:A2AB01|uniprotkb:A8MSS7|uniprotkb:Q8NDQ4|uniprotkb:A2AIB8|uniprotkb:Q9BRL9|uniprotkb:B7ZCV7|uniprotkb:Q8TF52|uniprotkb:Q6ZUJ6|uniprotkb:Q68CK8|uniprotkb:A4UBI6|uniprotkb:A6NCB7|ensembl:ENSP00000274853.3|ensembl:ENSP00000373067.4|ensembl:ENSP00000382150.3|ensembl:ENSP00000383400.3|ensembl:ENSP00000388790.2|ensembl:ENSP00000400129.2|ensembl:ENSP00000400990.2|ensembl:ENSP00000404066.2|ensembl:ENSP00000405234.2|ensembl:ENSP00000412456.2|ensembl:ENSP00000413596.2|ensembl:ENSP00000416648.2|ensembl:ENSP00000480270.1|uniprotkb:Q6ZTV1	psi-mi:q8d0r4_yerpe(display_long)|uniprotkb:ugpB3(gene name)|psi-mi:ugpB3(display_short)|uniprotkb:YP_2296(locus name)|uniprotkb:y1712(locus name)	psi-mi:ppr18_human(display_long)|uniprotkb:PPP1R18(gene name)|psi-mi:PPP1R18(display_short)|uniprotkb:HKMT1098(gene name synonym)|uniprotkb:KIAA1949(gene name synonym)|uniprotkb:Protein phosphatase 1 F-actin cytoskeleton-targeting subunit(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 18(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861363|imex:IM-13779-6628	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR050490|go:""GO:0016020""(membrane)|go:""GO:0030313""(cell envelope)"	"refseq:NP_001128342.1|refseq:NP_597728.1|ensembl:ENSG00000146112.12(gene)|ensembl:ENSG00000206485.10(gene)|ensembl:ENSG00000225060.8(gene)|ensembl:ENSG00000229998.8(gene)|ensembl:ENSG00000230341.8(gene)|ensembl:ENSG00000234000.8(gene)|ensembl:ENST00000274853.8(transcript)|ensembl:ENST00000383573.8(transcript)|ensembl:ENST00000399199.7(transcript)|ensembl:ENST00000400554.3(transcript)|ensembl:ENST00000437121.2(transcript)|ensembl:ENST00000438815.2(transcript)|ensembl:ENST00000438945.6(transcript)|ensembl:ENST00000443517.2(transcript)|ensembl:ENST00000444206.6(transcript)|ensembl:ENST00000449705.6(transcript)|ensembl:ENST00000451544.6(transcript)|ensembl:ENST00000455935.2(transcript)|ensembl:ENST00000615527.1(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0019902""(phosphatase binding)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671|mint:Q6NYC8|panther:PTHR21685(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WdQAdof8UnHcq+RBx3s9B0uCIlM632	rogid:63zpNZuwQb7VD0pOrr6yaRpPNmA9606	intact-crc:A239F1A690AE9535|rigid:C303B4XtuipI+rrOch/SDRnpBbg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WYR1	uniprotkb:A0A380PDG1	intact:EBI-2114827|uniprotkb:Q5G936|uniprotkb:Q5G938|uniprotkb:Q5G939|uniprotkb:Q8IZ23|uniprotkb:Q9Y2Y2|uniprotkb:D3DTS3|uniprotkb:B0LPH4|ensembl:ENSP00000392812.1|ensembl:ENSP00000462433.1	intact:EBI-2858548|uniprotkb:Q74TV6|uniprotkb:Q7CIL5|uniprotkb:A0A0H2W529	psi-mi:pi3r5_human(display_long)|uniprotkb:PIK3R5(gene name)|psi-mi:PIK3R5(display_short)|uniprotkb:PI3-kinase p101 subunit(gene name synonym)|uniprotkb:PtdIns-3-kinase p101(gene name synonym)|uniprotkb:p101-PI3K(gene name synonym)|uniprotkb:Protein FOAP-2(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit(gene name synonym)	psi-mi:a0a380pdg1_yerpe(display_long)|uniprotkb:acn(gene name)|psi-mi:acn(display_short)|uniprotkb:acnA(gene name synonym)|uniprotkb:YPO2221(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861344|imex:IM-13779-6624	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR15593(orthology-group)|efo:""Orphanet:64753""|ensembl:ENSG00000141506.15(gene)|ensembl:ENST00000447110.6(transcript)|ensembl:ENST00000581552.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005942""(phosphatidylinositol 3-kinase complex)|go:""GO:0005943""(phosphatidylinositol 3-kinase complex, class IA)|go:""GO:0005944""(phosphatidylinositol 3-kinase complex, class IB)|go:""GO:0006955""(immune response)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0031683""(G-protein beta/gamma-subunit complex binding)|go:""GO:0034451""(centriolar satellite)|go:""GO:0043406""(positive regulation of MAP kinase activity)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0046488""(phosphatidylinositol metabolic process)|go:""GO:0046935""(1-phosphatidylinositol-3-kinase regulator activity)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|interpro:IPR019522|mint:Q8WYR1|reactome:R-HSA-114604|reactome:R-HSA-1660499|reactome:R-HSA-392451|reactome:R-HSA-9027276|refseq:NP_001136105.1|refseq:NP_001238780.1|refseq:NP_001238781.1|refseq:NP_001238782.1|refseq:NP_001238784.1|refseq:NP_055123.2"	"interpro:IPR044137|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR018136|refseq:WP_002215187.1|go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006101""(citrate metabolic process)|go:""GO:0030350""(iron-responsive element binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR036008|refseq:YP_002347193.1|panther:PTHR11670(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ap0uqEqfwsD6FNJug53Qh5av/309606	rogid:U+Apr4nPvMOLOKyPanMpXDngrWk632	intact-crc:582926CC03C95EBF|rigid:7d0HAZyIA+CSIjDtzs1ECxTRC1w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0V9	uniprotkb:P42356	intact:EBI-2848637|uniprotkb:Q74SK8	intact:EBI-723050|uniprotkb:Q7Z625|uniprotkb:Q9UPG2|ensembl:ENSP00000255882.6|intact:EBI-11053324	psi-mi:q8d0v9_yerpe(display_long)|uniprotkb:dmsC2(gene name)|psi-mi:dmsC2(display_short)|uniprotkb:YP_2592(locus name)|uniprotkb:y1517(locus name)	psi-mi:pi4ka_human(display_long)|uniprotkb:PIK4CA(gene name synonym)|uniprotkb:PI4KA(gene name)|psi-mi:PI4KA(display_short)|uniprotkb:PIK4(gene name synonym)|uniprotkb:Phosphatidylinositol 4-Kinase III alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861337|imex:IM-13779-6626	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007059(""DMSO reductase anchor subunit (DmsC)"")|go:""GO:0016020""(membrane)|go:""GO:0019645""(anaerobic electron transport chain)"	"ensembl:ENSG00000241973.11(gene)|ensembl:ENST00000255882.11(transcript)|go:""GO:0004430""(1-phosphatidylinositol 4-kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|go:""GO:0030660""(Golgi-associated vesicle membrane)|go:""GO:0044788""(modulation by host of viral process)|go:""GO:0045296""(cadherin binding)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0048015""(phosphatidylinositol-mediated signaling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140754""(reorganization of cellular membranes to establish viral sites of replication)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR042236|interpro:IPR045495|mint:P42356|rcsb pdb:6BQ1|rcsb pdb:9B9G|reactome:R-HSA-1483248|reactome:R-HSA-1660514|refseq:NP_477352.3|efo:""Orphanet:436252""|efo:""Orphanet:631079""|efo:""Orphanet:98889""|panther:PTHR10048(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/Lc0yyHu5XkosmBiRlvq26qrMIY632	rogid:tm7wwZPJEvFMfK9xHMPLW9oYtzk9606	intact-crc:3F95E4C41E6DB4E3|rigid:rJHMf3kGBZX+PjVObitzzXqLKvI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D016	uniprotkb:Q8WV24	intact:EBI-2845497|uniprotkb:Q74WF8	intact:EBI-738731|uniprotkb:Q15184|uniprotkb:Q2TAN2|uniprotkb:Q9NZ17|uniprotkb:A1A4G9|ensembl:ENSP00000266671.5	psi-mi:q8d016_yerpe(display_long)|uniprotkb:melB1(gene name)|psi-mi:melB1(display_short)|uniprotkb:YP_0913(locus name)|uniprotkb:y2961(locus name)	psi-mi:phla1_human(display_long)|uniprotkb:PHLDA1(gene name)|psi-mi:PHLDA1(display_short)|uniprotkb:T-cell death-associated gene 51 protein(gene name synonym)|uniprotkb:Apoptosis-associated nuclear protein(gene name synonym)|uniprotkb:Proline- and histidine-rich protein(gene name synonym)|uniprotkb:Proline- and glutamine-rich protein(gene name synonym)|uniprotkb:PHRIP(gene name synonym)|uniprotkb:TDAG51(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861389|imex:IM-13779-6631	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039672|go:""GO:0008643""(carbohydrate transport)|go:""GO:0015293""(symporter activity)|go:""GO:0016020""(membrane)|interpro:IPR036259"	"refseq:NP_031376.3|ensembl:ENSG00000139289.15(gene)|ensembl:ENST00000266671.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045210""(obsolete FasL biosynthetic process)|go:""GO:1901981""(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR042832|mint:Q8WV24|reactome:R-HSA-8854521|reactome:R-HSA-9841922|panther:PTHR15478(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4DMhRYiG74JOcoym6GZ7F4fsxLM632	rogid:NS+bTnhkGzSYrQNsSRqehTkl0809606	intact-crc:B430B48D91EFD886|rigid:gAPFIXtXrArjjMhaRjg2uA2aPts	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UIL8	uniprotkb:A0A3G5L8E4	intact:EBI-2861403|uniprotkb:Q9Y5A2|uniprotkb:Q5W0A4|uniprotkb:Q5W0A6|ensembl:ENSP00000367570.3	intact:EBI-2855797	psi-mi:phf11_human(display_long)|uniprotkb:PHF11(gene name)|psi-mi:PHF11(display_short)|uniprotkb:BCAP(gene name synonym)|uniprotkb:BRCA1 C-terminus-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-34(gene name synonym)	psi-mi:a0a3g5l8e4_yerpe(display_long)|uniprotkb:y1719(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861410|imex:IM-13779-6630	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035533.1|refseq:NP_001035534.1|ensembl:ENSG00000136147.18(gene)|ensembl:ENST00000378319.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0031965""(nuclear membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR051188|panther:PTHR12420(orthology-group)"	uniprotkb:A0A2U2H0Q4(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uLVoCArn8KdXXrKbjPxwf1foxbg9606	rogid:c6G8UaA9FOgYFgSiLNHnP1AxUhU632	intact-crc:1413CA335DBAA1D8|rigid:HAsQXGHUhDKJMZfasCziQ5g2c5Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TCD6	uniprotkb:Q8D131	intact:EBI-2861380|uniprotkb:B2RC30|uniprotkb:D3DPC7|ensembl:ENSP00000352782.3|ensembl:ENSP00000481046.1|ensembl:ENSP00000481680.1|ensembl:ENSP00000481857.1	intact:EBI-2858378|uniprotkb:Q74VY8	psi-mi:phop2_human(display_long)|uniprotkb:PHOSPHO2(gene name)|psi-mi:PHOSPHO2(display_short)	psi-mi:q8d131_yerpe(display_long)|uniprotkb:mviM1(gene name)|psi-mi:mviM1(display_short)|uniprotkb:YP_1131(locus name)|uniprotkb:y1152(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861377|imex:IM-13779-6629	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001008489.1|refseq:NP_001186214.1|refseq:NP_001186215.1|refseq:NP_001186216.1|refseq:NP_001186217.1|ensembl:ENSG00000144362.12(gene)|ensembl:ENST00000359744.8(transcript)|ensembl:ENST00000616481.4(transcript)|ensembl:ENST00000616524.4(transcript)|ensembl:ENST00000617738.4(transcript)|go:""GO:0016791""(phosphatase activity)|go:""GO:0033883""(pyridoxal phosphatase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR006384(HAD-superfamily hydrolase, subfamily IB, hypothetical 1)|interpro:IPR016965(Pyridoxal phosphate phosphatase, PHOSPHO2)|interpro:IPR023214|interpro:IPR036412|panther:PTHR20889(orthology-group)"	"interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR050463|go:""GO:0000166""(nucleotide binding)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR055170|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WjrE0/DyyUfLH0ABTHmjXqUKSUI9606	rogid:A5TCBtioM6Hbyj2QQ+aVDQPo8D8632	intact-crc:08A6A6570A5E637B|rigid:aDURpc7eK0k8EV5skmfVL2VIsZs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q65AE7	uniprotkb:O43189	intact:EBI-2847916|uniprotkb:A0A3N4BMH0|uniprotkb:Q9ZGZ5|uniprotkb:A0A384LBG0|uniprotkb:A0A1U8QRS1|uniprotkb:Q7ARB3	intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640.3|ensembl:ENSP00000391901.2|ensembl:ENSP00000407295.2	psi-mi:q65ae7_yerpe(display_long)|uniprotkb:YPMT1.73(locus name)	psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861396|imex:IM-13779-6632	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025202|refseq:WP_002211757.1|refseq:NP_395419.1|refseq:YP_094002.1|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|interpro:IPR051406"	"refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511.18(gene)|ensembl:ENSG00000225553.7(gene)|ensembl:ENST00000374516.8(transcript)|ensembl:ENST00000427869.6(transcript)|ensembl:ENST00000454914.6(transcript)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042802""(identical protein binding)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0046872""(metal ion binding)|go:""GO:0140861""(DNA repair-dependent chromatin remodeling)|go:""GO:1990226""(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|interpro:IPR047010|interpro:IPR047399|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|rcsb pdb:7LKY|rcsb pdb:8H43|reactome:R-HSA-212300|dip:DIP-34001N|panther:PTHR12628(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/17	rogid:BaOKn4oWF9wcKgOoNSaPk58oQ6k632	rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606	intact-crc:08DF988B01535264|rigid:Kbqqsn5d5Sr7OvzGn2gRcHCdE9U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BS13	uniprotkb:P21810	intact:EBI-2851217|uniprotkb:Q74VF8|uniprotkb:A0A0H2W4A8|uniprotkb:Q7CHM6|uniprotkb:A0A384L9B9	intact:EBI-762076|uniprotkb:P13247|ensembl:ENSP00000327336.4|uniprotkb:D3DWU3	psi-mi:a0a3n4bs13_yerpe(display_long)|uniprotkb:YPO1460(locus name)	psi-mi:pgs1_human(display_long)|uniprotkb:SLRR1A(gene name synonym)|uniprotkb:Bone/cartilage proteoglycan I(gene name synonym)|uniprotkb:PG-S1(gene name synonym)|uniprotkb:BGN(gene name)|psi-mi:BGN(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861454|imex:IM-13779-6635	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002347(Glucose/ribitol dehydrogenase)|refseq:WP_002213024.1|go:""GO:0005829""(cytosol)|go:""GO:0008709""(""cholate 7-alpha-dehydrogenase (NAD+) activity"")|interpro:IPR036291|refseq:YP_002346478.1|interpro:IPR052178|panther:PTHR43618(orthology-group)"	"ensembl:ENSG00000182492.16(gene)|ensembl:ENST00000331595.9(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005796""(Golgi lumen)|go:""GO:0009986""(cell surface)|go:""GO:0019955""(cytokine binding)|go:""GO:0030021""(extracellular matrix structural constituent conferring compression resistance)|go:""GO:0030133""(transport vesicle)|go:""GO:0031012""(extracellular matrix)|go:""GO:0042383""(sarcolemma)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0060348""(bone development)|go:""GO:0061975""(articular cartilage development)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR032675|interpro:IPR050333|mint:P21810|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332|refseq:NP_001702.1|refseq:XP_016885213.1|efo:""Orphanet:622925""|efo:""Orphanet:93349""|panther:PTHR45712(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7LflFBMVJDkIvr5R4pLM/KSUWJM632	rogid:G7A6TRMpSIqTBpXtm67XG0GfM2w9606	intact-crc:09FA337F5A88F73E|rigid:kPm1/sApKPu9XLtWYjuMXMW/p0k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D111	uniprotkb:P00439	intact:EBI-2861439|uniprotkb:Q74ST5	intact:EBI-2861444|uniprotkb:Q16717|uniprotkb:Q8TC14|ensembl:ENSP00000448059.1	psi-mi:q8d111_yerpe(display_long)|uniprotkb:YP_2488(locus name)|uniprotkb:pgm(gene name)|psi-mi:pgm(display_short)|uniprotkb:y1258(locus name)	psi-mi:ph4h_human(display_long)|uniprotkb:PAH(gene name)|psi-mi:PAH(display_short)|uniprotkb:Phe-4-monooxygenase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861436|imex:IM-13779-6634	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR005852(Phosphoglucomutase, alpha-D-glucose specific)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004614""(phosphoglucomutase activity)|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR036900|interpro:IPR045244"	"dip:DIP-58927N|ensembl:ENSG00000171759.10(gene)|ensembl:ENST00000553106.6(transcript)|go:""GO:0004505""(phenylalanine 4-monooxygenase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006559""(L-phenylalanine catabolic process)|go:""GO:0006571""(tyrosine biosynthetic process)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0042423""(catecholamine biosynthetic process)|interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR005961(Phenylalanine-4-hydroxylase, tetrameric form)|interpro:IPR018301|interpro:IPR019773|interpro:IPR019774|interpro:IPR036329|interpro:IPR036951|interpro:IPR041912|interpro:IPR045865|mint:P00439|rcsb pdb:1DMW|rcsb pdb:1J8T|rcsb pdb:1J8U|rcsb pdb:1KW0|rcsb pdb:1LRM|rcsb pdb:1MMK|rcsb pdb:1MMT|rcsb pdb:1PAH|rcsb pdb:1TDW|rcsb pdb:1TG2|rcsb pdb:2PAH|rcsb pdb:3PAH|rcsb pdb:4ANP|rcsb pdb:4PAH|rcsb pdb:5FII|rcsb pdb:5PAH|rcsb pdb:6HPO|rcsb pdb:6HYC|rcsb pdb:6N1K|rcsb pdb:6PAH|reactome:R-HSA-2160456|reactome:R-HSA-8964208|refseq:NP_000268.1|efo:""Orphanet:2209""|efo:""Orphanet:293284""|efo:""Orphanet:79253""|efo:""Orphanet:79254""|efo:""Orphanet:79651""|panther:PTHR11473(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PGJw60njk7gqdQFTWuAaZMcLotY632	rogid:byO1PdD6RTWtUZOt5A9/N/Gl4Do9606	intact-crc:20D6ADA2AAA2152F|rigid:BLP9tgchL5j4TLaTIHgVU1kLHQA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UIL8	uniprotkb:A0A5P8YEA2	intact:EBI-2861403|uniprotkb:Q9Y5A2|uniprotkb:Q5W0A4|uniprotkb:Q5W0A6|ensembl:ENSP00000367570.3	intact:EBI-2861417|uniprotkb:Q74UV2|uniprotkb:Q7CHX7|uniprotkb:Q0WFZ3	psi-mi:phf11_human(display_long)|uniprotkb:PHF11(gene name)|psi-mi:PHF11(display_short)|uniprotkb:BCAP(gene name synonym)|uniprotkb:BRCA1 C-terminus-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-34(gene name synonym)	psi-mi:a0a5p8yea2_yerpe(display_long)|uniprotkb:fla FIII(gene name)|psi-mi:fla FIII(display_short)|uniprotkb:flaW(gene name synonym)|uniprotkb:flgC(gene name synonym)|uniprotkb:YPO1800(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861422|imex:IM-13779-6633	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035533.1|refseq:NP_001035534.1|ensembl:ENSG00000136147.18(gene)|ensembl:ENST00000378319.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0031965""(nuclear membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR051188|panther:PTHR12420(orthology-group)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|interpro:IPR019776|refseq:WP_002211111.1|go:""GO:0009288""(bacterial-type flagellum)|go:""GO:0030694""(bacterial-type flagellum basal body, rod)|go:""GO:0071978""(bacterial-type flagellum-dependent swarming motility)|refseq:YP_002346795.1|panther:PTHR30435(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uLVoCArn8KdXXrKbjPxwf1foxbg9606	rogid:IPad3QczYFbhm4NcCZEc4DH5FaE632	intact-crc:95E1237778C33593|rigid:rJfCY7KKkVzOoE9t3I9gJSe5u9Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P21810	uniprotkb:A0A2U2GV98	intact:EBI-762076|uniprotkb:P13247|ensembl:ENSP00000327336.4|uniprotkb:D3DWU3	intact:EBI-2842935|uniprotkb:Q0WA52|uniprotkb:Q7CG01|uniprotkb:A0A380PFZ4|uniprotkb:A0A384KIG3	psi-mi:pgs1_human(display_long)|uniprotkb:SLRR1A(gene name synonym)|uniprotkb:Bone/cartilage proteoglycan I(gene name synonym)|uniprotkb:PG-S1(gene name synonym)|uniprotkb:BGN(gene name)|psi-mi:BGN(display_short)	psi-mi:a0a2u2gv98_yerpe(display_long)|uniprotkb:YPO3965(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861461|imex:IM-13779-6637	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000182492.16(gene)|ensembl:ENST00000331595.9(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005796""(Golgi lumen)|go:""GO:0009986""(cell surface)|go:""GO:0019955""(cytokine binding)|go:""GO:0030021""(extracellular matrix structural constituent conferring compression resistance)|go:""GO:0030133""(transport vesicle)|go:""GO:0031012""(extracellular matrix)|go:""GO:0042383""(sarcolemma)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0060348""(bone development)|go:""GO:0061975""(articular cartilage development)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR032675|interpro:IPR050333|mint:P21810|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332|refseq:NP_001702.1|refseq:XP_016885213.1|efo:""Orphanet:622925""|efo:""Orphanet:93349""|panther:PTHR45712(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR000014(PAS)|interpro:IPR005467(Signal transduction histidine kinase, core)|refseq:WP_002209524.1|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0016020""(membrane)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|refseq:YP_002348836.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:G7A6TRMpSIqTBpXtm67XG0GfM2w9606	rogid:l6f5EnoNPBCpn3IKEDOJAOvm7+w632	intact-crc:5FA754C24D984189|rigid:aoqYTxBsroff8g87wuxQtUG+N9k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YJ66	uniprotkb:Q9UIL8	intact:EBI-2850046|uniprotkb:Q74RM6|uniprotkb:A0A2U2H1F0|uniprotkb:A0A0H2W677|uniprotkb:Q7CGI7|uniprotkb:A0A384KU41	intact:EBI-2861403|uniprotkb:Q9Y5A2|uniprotkb:Q5W0A4|uniprotkb:Q5W0A6|ensembl:ENSP00000367570.3	psi-mi:a0a5p8yj66_yerpe(display_long)|uniprotkb:YPO0684(locus name)	psi-mi:phf11_human(display_long)|uniprotkb:PHF11(gene name)|psi-mi:PHF11(display_short)|uniprotkb:BCAP(gene name synonym)|uniprotkb:BRCA1 C-terminus-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-34(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861429|imex:IM-13779-6636	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002212169.1|interpro:IPR036465|refseq:YP_002345750.1	"refseq:NP_001035533.1|refseq:NP_001035534.1|ensembl:ENSG00000136147.18(gene)|ensembl:ENST00000378319.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0031965""(nuclear membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR051188|panther:PTHR12420(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KizmEigIJwb1SmlvV0RiTRhkoTQ632	rogid:uLVoCArn8KdXXrKbjPxwf1foxbg9606	intact-crc:1F9DA8EC17A73FD3|rigid:XSx1eTs3eiSy2kgTN4VngGj9jvc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00558	uniprotkb:Q8ZA76	intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413.4	intact:EBI-2846943|uniprotkb:Q0WA76	psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name)	psi-mi:glgx_yerpe(display_long)|uniprotkb:glgX(gene name)|psi-mi:glgX(display_short)|uniprotkb:Limit dextrin alpha-1,6-maltotetraose-hydrolase(gene name synonym)|uniprotkb:YPO3941(locus name)|uniprotkb:YP_3303(locus name)|uniprotkb:y3887(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861512|imex:IM-13779-6640	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:713""|dip:DIP-33679N|ensembl:ENSG00000102144.15(gene)|ensembl:ENST00000373316.5(transcript)|go:""GO:0004618""(phosphoglycerate kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031639""(plasminogen activation)|go:""GO:0043531""(ADP binding)|go:""GO:0045121""(membrane raft)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0061621""(canonical glycolysis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0160218""(negative regulation of acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|rcsb pdb:8YHP|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|refseq:NP_000282.1|panther:PTHR11406(orthology-group)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR022844|interpro:IPR011837(Glycogen debranching enzyme GlgX)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR040784|go:""GO:0004133""(obsolete glycogen debranching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005980""(glycogen catabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_002209499.1|interpro:IPR044505|refseq:YP_002348812.1|panther:PTHR43002(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606	rogid:8sHtj0obGqvrIdGE1JWk8okcbRM632	intact-crc:113AE696CF293A87|rigid:zOuKV5NIhOwEOA3iHfC4iM3vMng	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D194	uniprotkb:P36871	intact:EBI-2847851|uniprotkb:Q74XR4	intact:EBI-2861475|uniprotkb:Q5BKZ9|uniprotkb:Q96J40|uniprotkb:Q9NTY4|uniprotkb:Q6NW22|uniprotkb:Q86U74|uniprotkb:Q16105|uniprotkb:B2R5N9|uniprotkb:B4DPV0|uniprotkb:Q16106|ensembl:ENSP00000360125.3	psi-mi:q8d194_yerpe(display_long)|uniprotkb:dAK1_1(gene name)|psi-mi:dAK1_1(display_short)|uniprotkb:YP_0337(locus name)|uniprotkb:y0840(locus name)	psi-mi:pgm1_human(display_long)|uniprotkb:PGM1(gene name)|psi-mi:PGM1(display_short)|uniprotkb:Glucose phosphomutase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861486|imex:IM-13779-6638	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004006(Dak kinase)|go:""GO:0004371""(glycerone kinase activity)|go:""GO:0006071""(glycerol metabolic process)|interpro:IPR050861"	"ensembl:ENSG00000079739.17(gene)|ensembl:ENST00000371084.8(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004614""(phosphoglucomutase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0033499""(galactose catabolic process via UDP-galactose, Leloir pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900|interpro:IPR045244|mint:P36871|rcsb pdb:5EPC|rcsb pdb:5F9C|rcsb pdb:5HSH|rcsb pdb:5JN5|rcsb pdb:5TR2|rcsb pdb:5VBI|rcsb pdb:5VEC|rcsb pdb:5VG7|rcsb pdb:5VIN|rcsb pdb:6SNO|rcsb pdb:6SNP|rcsb pdb:6SNQ|rcsb pdb:6UIQ|rcsb pdb:6UO6|rcsb pdb:7S0W|rcsb pdb:7S77|reactome:R-HSA-3322077|reactome:R-HSA-5609974|reactome:R-HSA-6798695|reactome:R-HSA-70221|reactome:R-HSA-70370|refseq:NP_001166289.1|refseq:NP_001166290.1|refseq:NP_002624.2|dip:DIP-60903N|efo:""Orphanet:319646""|panther:PTHR22573(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:PGSwAYXIFUUnJmzpLaHT1vlvQxc632	rogid:K9cGu3lfysJ4hVP0S0jewZsZjSE9606	intact-crc:B8CBC8A1DF2D3443|rigid:GpgIIlEDUsgTgjKd6ikn0VValn4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P21810	uniprotkb:Q7ARD3	intact:EBI-762076|uniprotkb:P13247|ensembl:ENSP00000327336.4|uniprotkb:D3DWU3	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:pgs1_human(display_long)|uniprotkb:SLRR1A(gene name synonym)|uniprotkb:Bone/cartilage proteoglycan I(gene name synonym)|uniprotkb:PG-S1(gene name synonym)|uniprotkb:BGN(gene name)|psi-mi:BGN(display_short)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861468|imex:IM-13779-6642	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000182492.16(gene)|ensembl:ENST00000331595.9(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005796""(Golgi lumen)|go:""GO:0009986""(cell surface)|go:""GO:0019955""(cytokine binding)|go:""GO:0030021""(extracellular matrix structural constituent conferring compression resistance)|go:""GO:0030133""(transport vesicle)|go:""GO:0031012""(extracellular matrix)|go:""GO:0042383""(sarcolemma)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0060348""(bone development)|go:""GO:0061975""(articular cartilage development)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR032675|interpro:IPR050333|mint:P21810|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332|refseq:NP_001702.1|refseq:XP_016885213.1|efo:""Orphanet:622925""|efo:""Orphanet:93349""|panther:PTHR45712(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:G7A6TRMpSIqTBpXtm67XG0GfM2w9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:71F6E22E4C19BD19|rigid:90BglbTZkBsg97RXOs6QLuxpbiI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00558	uniprotkb:Q0WC81	intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413.4	intact:EBI-2861496|uniprotkb:A0A2U2GYW8|uniprotkb:Q74WV2|uniprotkb:A0A0H2W258|uniprotkb:Q7CK51|uniprotkb:A0A384KKF8	psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name)	psi-mi:q0wc81_yerpe(display_long)|uniprotkb:pstS(gene name)|psi-mi:pstS(display_short)|uniprotkb:YPO3203(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861493|imex:IM-13779-6641	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:713""|dip:DIP-33679N|ensembl:ENSG00000102144.15(gene)|ensembl:ENST00000373316.5(transcript)|go:""GO:0004618""(phosphoglycerate kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031639""(plasminogen activation)|go:""GO:0043531""(ADP binding)|go:""GO:0045121""(membrane raft)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0061621""(canonical glycolysis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0160218""(negative regulation of acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|rcsb pdb:8YHP|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|refseq:NP_000282.1|panther:PTHR11406(orthology-group)"	"interpro:IPR011862(Phosphate binding protein)|interpro:IPR024370|interpro:IPR050811|go:""GO:0005576""(extracellular region)|go:""GO:0006817""(phosphate ion transport)|go:""GO:0007155""(cell adhesion)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348107.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606	rogid:eGs2Apb3O5ykccf4QwsRs5eYsA0632	intact-crc:A4ACC14046BCB754|rigid:XjaUwMoLplIpe9JTnCYaajcN74U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00558	uniprotkb:Q7ARH3	intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413.4	intact:EBI-2849426|uniprotkb:A0A384KLR8|uniprotkb:O68711|uniprotkb:Q74YV0|uniprotkb:A0A0H2W092|uniprotkb:A0A2U2GVE2	psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name)	psi-mi:q7arh3_yerpe(display_long)|uniprotkb:tnpA(gene name)|psi-mi:tnpA(display_short)|uniprotkb:YPCD1.90c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861505|imex:IM-13779-6639	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:713""|dip:DIP-33679N|ensembl:ENSG00000102144.15(gene)|ensembl:ENST00000373316.5(transcript)|go:""GO:0004618""(phosphoglycerate kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031639""(plasminogen activation)|go:""GO:0043531""(ADP binding)|go:""GO:0045121""(membrane raft)|go:""GO:0047134""(""protein-disulfide reductase [NAD(P)H] activity"")|go:""GO:0061621""(canonical glycolysis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0160218""(negative regulation of acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|rcsb pdb:8YHP|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|refseq:NP_000282.1|panther:PTHR11406(orthology-group)"	"refseq:NP_857769.1|interpro:IPR002513(Transposase, Tn3)|refseq:NP_395219.1|interpro:IPR025296|interpro:IPR047653|refseq:WP_002213256.1|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606	rogid:00nBYkSaVEOjkb6Bm6Lk/llhQRc632	intact-crc:966F8A641117BC18|rigid:6am0A88/2ZPI4NY0wyhcnZzC3hE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96BD5	uniprotkb:Q8ZJP8	intact:EBI-745085|uniprotkb:Q6AWA2|uniprotkb:Q9C0G7|uniprotkb:Q9H8V9|uniprotkb:Q9HAK6|uniprotkb:Q9NZE9|uniprotkb:D3DQP5|ensembl:ENSP00000398824.2	intact:EBI-2847365|uniprotkb:Q0WKP8	psi-mi:pf21a_human(display_long)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name)	psi-mi:rnph_yerpe(display_long)|uniprotkb:rph(gene name)|psi-mi:rph(display_short)|uniprotkb:tRNA nucleotidyltransferase(gene name synonym)|uniprotkb:YPO0044(locus name)|uniprotkb:y0097(locus name)|uniprotkb:YP_0045(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861541|imex:IM-13779-6644	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:52022""|dip:DIP-60252N|ensembl:ENSG00000135365.17(gene)|ensembl:ENST00000418153.6(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0046872""(metal ion binding)|go:""GO:1990391""(DNA repair complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q96BD5|rcsb pdb:2PUY|rcsb pdb:2YQL|reactome:R-HSA-3214815|reactome:R-HSA-9679191|reactome:R-HSA-983231|refseq:NP_001095272.1|refseq:NP_057705.3|refseq:XP_005253022.1|refseq:XP_011518475.1|refseq:XP_011518476.1|refseq:XP_011518481.1|refseq:XP_016873380.1|panther:PTHR24102(orthology-group)"	"interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR002381(Ribonuclease phosphorolytic, bacterial-type)|interpro:IPR018336|interpro:IPR027408|refseq:WP_002208997.1|go:""GO:0000049""(tRNA binding)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0003723""(RNA binding)|go:""GO:0006364""(rRNA processing)|go:""GO:0008033""(tRNA processing)|go:""GO:0009022""(tRNA nucleotidyltransferase activity)|go:""GO:0016075""(rRNA catabolic process)|interpro:IPR036345|refseq:YP_002345140.1|interpro:IPR050080|panther:PTHR11953(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/12	rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606	rogid:w1ahukqHBCGll+OW4Q9GEEimgOY632	intact-crc:E0FBD19071541FA2|rigid:ZQZyL8JjAJ6fUXfal4hJIazcqbQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50542	uniprotkb:Q8CLD7	intact:EBI-597835|uniprotkb:Q15115|uniprotkb:Q15266|uniprotkb:Q96FN7|uniprotkb:B7ZAD5|ensembl:ENSP00000400647.2|ensembl:ENSP00000410159.2|ensembl:ENSP00000499823.1|ensembl:ENSP00000500509.1|ensembl:ENSP00000502374.1|uniprotkb:A8K891|uniprotkb:D3DUT8|uniprotkb:B4DZ45|intact:EBI-28971432	intact:EBI-2861558	psi-mi:pex5_human(display_long)|uniprotkb:Peroxisome receptor 1(gene name synonym)|uniprotkb:Peroxisomal C-terminal targeting signal import receptor(gene name synonym)|uniprotkb:PTS1-BP(gene name synonym)|uniprotkb:Peroxin-5(gene name synonym)|uniprotkb:PEX5(gene name)|psi-mi:PEX5(display_short)|uniprotkb:PXR1(gene name synonym)	psi-mi:q8cld7_yerpe(display_long)|uniprotkb:y1555(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861555|imex:IM-13779-6647	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000139197.11(gene)|ensembl:ENSG00000288217.3(gene)|ensembl:ENST00000420616.6(transcript)|ensembl:ENST00000455147.6(transcript)|ensembl:ENST00000671993.1(transcript)|ensembl:ENST00000672694.1(transcript)|ensembl:ENST00000675855.1(transcript)|go:""GO:0000038""(very long-chain fatty acid metabolic process)|go:""GO:0000268""(peroxisome targeting sequence binding)|go:""GO:0000425""(pexophagy)|go:""GO:0001764""(neuron migration)|go:""GO:0005052""(peroxisome matrix targeting signal-1 binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006625""(protein targeting to peroxisome)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0007006""(mitochondrial membrane organization)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0016020""(membrane)|go:""GO:0016558""(protein import into peroxisome matrix)|go:""GO:0016560""(protein import into peroxisome matrix, docking)|go:""GO:0016561""(protein import into peroxisome matrix, translocation)|go:""GO:0016562""(protein import into peroxisome matrix, receptor recycling)|go:""GO:0019899""(enzyme binding)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0021895""(cerebral cortex neuron differentiation)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033328""(peroxisome membrane targeting sequence binding)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0040018""(positive regulation of multicellular organism growth)|go:""GO:0044721""(protein import into peroxisome matrix, substrate release)|go:""GO:0045046""(protein import into peroxisome membrane)|go:""GO:0048468""(cell development)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051262""(protein tetramerization)|go:""GO:0140597""(protein carrier chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|mint:P50542|rcsb pdb:1FCH|rcsb pdb:2C0L|rcsb pdb:2C0M|rcsb pdb:2J9Q|rcsb pdb:2W84|rcsb pdb:3R9A|rcsb pdb:4BXU|rcsb pdb:4KXK|rcsb pdb:4KYO|rcsb pdb:7Z0K|rcsb pdb:9GAG|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9664873|refseq:NP_000310.2|refseq:NP_001124495.1|refseq:NP_001124496.1|refseq:NP_001124497.1|refseq:NP_001124498.1|refseq:NP_001287718.1|refseq:XP_011519097.1|refseq:XP_011519099.1|refseq:XP_011519100.1|refseq:XP_011519101.1|refseq:XP_011519102.1|refseq:XP_016875237.1|refseq:XP_016875238.1|refseq:XP_016875239.1|refseq:XP_016875241.1|refseq:XP_016875242.1|refseq:XP_016875243.1|refseq:XP_016875244.1|dip:DIP-34654N|efo:""Orphanet:44""|efo:""Orphanet:468717""|efo:""Orphanet:772""|efo:""Orphanet:912""|panther:PTHR10130(orthology-group)"	refseq:WP_011055427.1|interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eTada01hgbdLE6GcBY29EGX+7QI9606	rogid:t97jqkb6CIQEiwf20PLjH54YoSU632	intact-crc:819A6A92C9DACCAC|rigid:6O9gXux+e5vQPsISzR7PQRBomj8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UHV9	uniprotkb:A0A3G5L2Q1	intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989.3	intact:EBI-2845751	psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym)	psi-mi:a0a3g5l2q1_yerpe(display_long)|uniprotkb:rcsD_1(gene name)|psi-mi:rcsD_1(display_short)|uniprotkb:NCTC5923_01909(orf name)|uniprotkb:y2968(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861534|imex:IM-13779-6646	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036526.2|ensembl:ENSG00000143256.5(gene)|ensembl:ENST00000368010.4(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0016272""(prefoldin complex)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051495""(positive regulation of cytoskeleton organization)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1905907""(negative regulation of amyloid fibril formation)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:7WU7|reactome:R-HSA-389957|refseq:XP_011507926.1|dip:DIP-27557N|panther:PTHR13303(orthology-group)"	"uniprotkb:A0A6B3T660(uniprot-removed-ac)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036890|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0016020""(membrane)|go:""GO:0016740""(transferase activity)|refseq:WP_002216093.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606	rogid:r4uXUojxy6U1CFud51vTXRXZz/k632	intact-crc:B14D1A86B2659148|rigid:9M7VeH3S+jERWnApliS8y2ksz0A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKF8	uniprotkb:P16234	intact:EBI-2844579|uniprotkb:Q74RR5	intact:EBI-2861522|uniprotkb:Q96KZ7|uniprotkb:B2RE69|uniprotkb:Q9UD28|uniprotkb:E9PBH0|uniprotkb:Q6P4H5|ensembl:ENSP00000257290.5	psi-mi:q8ckf8_yerpe(display_long)|uniprotkb:y3542(locus name)	psi-mi:pgfra_human(display_long)|uniprotkb:PDGFRA(gene name)|psi-mi:PDGFRA(display_short)|uniprotkb:CD140 antigen-like family member A(gene name synonym)|uniprotkb:CD140a antigen(gene name synonym)|uniprotkb:Alpha-type platelet-derived growth factor receptor(gene name synonym)|uniprotkb:Alpha platelet-derived growth factor receptor(gene name synonym)|uniprotkb:Platelet-derived growth factor receptor 2(gene name synonym)|uniprotkb:RHEPDGFRA(gene name synonym)|uniprotkb:PDGFR2(gene name synonym)|uniprotkb:Platelet-derived growth factor alpha receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861519|imex:IM-13779-6643	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR037883	"dip:DIP-5736N|ensembl:ENSG00000134853.12(gene)|ensembl:ENST00000257290.10(transcript)|go:""GO:0001553""(luteinization)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001775""(cell activation)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005161""(platelet-derived growth factor receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005929""(cilium)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008210""(estrogen metabolic process)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010544""(negative regulation of platelet activation)|go:""GO:0016020""(membrane)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0023019""(signal transduction involved in regulation of gene expression)|go:""GO:0030054""(cell junction)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030324""(lung development)|go:""GO:0030325""(adrenal gland development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030539""(male genitalia development)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033327""(Leydig cell differentiation)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035790""(platelet-derived growth factor receptor-alpha signaling pathway)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0038085""(vascular endothelial growth factor binding)|go:""GO:0038091""(positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway)|go:""GO:0042060""(wound healing)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043235""(receptor complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048407""(platelet-derived growth factor binding)|go:""GO:0048557""(embryonic digestive tract morphogenesis)|go:""GO:0048701""(embryonic cranial skeleton morphogenesis)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0050872""(white fat cell differentiation)|go:""GO:0050921""(positive regulation of chemotaxis)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055003""(cardiac myofibril assembly)|go:""GO:0060021""(roof of mouth development)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0061298""(retina vasculature development in camera-type eye)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0072277""(metanephric glomerular capillary formation)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0160185""(phospholipase C activator activity)|go:""GO:2000739""(regulation of mesenchymal stem cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027290|interpro:IPR036179|interpro:IPR050122|mint:P16234|rcsb pdb:1GQ5|rcsb pdb:5GRN|rcsb pdb:5K5X|rcsb pdb:6A32|rcsb pdb:6JOI|rcsb pdb:6JOJ|rcsb pdb:6JOK|rcsb pdb:6JOL|rcsb pdb:7LBF|rcsb pdb:7RAM|rcsb pdb:8PQH|rcsb pdb:8PQI|rcsb pdb:8PQJ|rcsb pdb:8PQK|reactome:R-HSA-1257604|reactome:R-HSA-186763|reactome:R-HSA-186797|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674396|reactome:R-HSA-9674401|reactome:R-HSA-9674403|reactome:R-HSA-9674404|reactome:R-HSA-9674428|refseq:NP_001334758.1|refseq:NP_006197.1|refseq:XP_005265800.1|efo:""Orphanet:168940""|efo:""Orphanet:168947""|efo:""Orphanet:199306""|efo:""Orphanet:314950""|efo:""Orphanet:44890""|efo:""Orphanet:585877""|panther:PTHR24416(orthology-group)|ensembl:ENSP00000257290.5|ensembl:ENST00000508170.5|ensembl:ENSP00000425648.1|ensembl:ENST00000509490.5|ensembl:ENSP00000424218.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bULfeL7EI8ZLrm+OLqILFkvARMg632	rogid:MkKEhNlBrHysJ4mct8Rvqjy2f7U9606	intact-crc:99CCA6FE501B966D|rigid:p0OIMjRp0OATXftpLwN7Yb5YkCI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96BD5	uniprotkb:A0A2U2GYU0	intact:EBI-745085|uniprotkb:Q6AWA2|uniprotkb:Q9C0G7|uniprotkb:Q9H8V9|uniprotkb:Q9HAK6|uniprotkb:Q9NZE9|uniprotkb:D3DQP5|ensembl:ENSP00000398824.2	intact:EBI-2847562|uniprotkb:A0A380PDR3|uniprotkb:Q0WFV2|uniprotkb:Q7CI00|uniprotkb:A0A384KNN0	psi-mi:pf21a_human(display_long)|uniprotkb:BRAF35-HDAC complex protein BHC80(gene name synonym)|uniprotkb:BHC80a(gene name synonym)|uniprotkb:PHF21A(gene name)|psi-mi:PHF21A(display_short)|uniprotkb:BHC80(gene name synonym)|uniprotkb:KIAA1696(gene name synonym)|uniprotkb:BM-006(orf name)	psi-mi:a0a2u2gyu0_yerpe(display_long)|uniprotkb:flaF(gene name)|psi-mi:flaF(display_short)|uniprotkb:fliC(gene name synonym)|uniprotkb:hag(gene name synonym)|uniprotkb:YPO1842(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861548|imex:IM-13779-6645	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:52022""|dip:DIP-60252N|ensembl:ENSG00000135365.17(gene)|ensembl:ENST00000418153.6(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0046872""(metal ion binding)|go:""GO:1990391""(DNA repair complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q96BD5|rcsb pdb:2PUY|rcsb pdb:2YQL|reactome:R-HSA-3214815|reactome:R-HSA-9679191|reactome:R-HSA-983231|refseq:NP_001095272.1|refseq:NP_057705.3|refseq:XP_005253022.1|refseq:XP_011518475.1|refseq:XP_011518476.1|refseq:XP_011518481.1|refseq:XP_016873380.1|panther:PTHR24102(orthology-group)"	"interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR042187|refseq:WP_002211152.1|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009288""(bacterial-type flagellum)|refseq:YP_002346836.1|interpro:IPR046358"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/12	rogid:pWfOJSiI9cq6K41jSU3VOxT+u9c9606	rogid:0iQC5KNYj/iy3Dwyc0YTHeiyqhs632	intact-crc:D0D06B274DB86BC3|rigid:PH0/hqnZpsfvVHTjHgv7A82mYqE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43116	uniprotkb:A0A5P8YBY3	intact:EBI-2861591|uniprotkb:Q52LG8|uniprotkb:D3DSC0|ensembl:ENSP00000245457.5	intact:EBI-2861596|uniprotkb:Q74X97|uniprotkb:Q0WBB9|uniprotkb:Q7CKK9|uniprotkb:A0A0H2W1T3|uniprotkb:A0A384LMS9	psi-mi:pe2r2_human(display_long)|uniprotkb:PTGER2(gene name)|psi-mi:PTGER2(display_short)|uniprotkb:Prostanoid EP2 receptor(gene name synonym)	psi-mi:a0a5p8yby3_yerpe(display_long)|uniprotkb:cpdB(gene name)|psi-mi:cpdB(display_short)|uniprotkb:YPO3530(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861601|imex:IM-13779-6651	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000947.2|ensembl:ENSG00000125384.8(gene)|ensembl:ENST00000245457.6(transcript)|go:""GO:0004957""(prostaglandin E receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0009624""(response to nematode)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032570""(response to progesterone)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0071380""(cellular response to prostaglandin E stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001923(Prostanoid EP2 receptor)|interpro:IPR008365(Prostanoid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|reactome:R-HSA-391908|reactome:R-HSA-418555|panther:PTHR11866(orthology-group)"	"interpro:IPR029052|interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR006294(2 ,3 -cyclic-nucleotide 2 -phosphodiesterase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006146(5'-Nucleotidase, conserved site)|refseq:WP_002210160.1|rcsb pdb:5EQV|go:""GO:0000166""(nucleotide binding)|go:""GO:0008252""(nucleotidase activity)|go:""GO:0008663""(2',3'-cyclic-nucleotide 2'-phosphodiesterase activity)|go:""GO:0009166""(nucleotide catabolic process)|go:""GO:0030313""(cell envelope)|go:""GO:0046872""(metal ion binding)|interpro:IPR036907|interpro:IPR041827|refseq:YP_002348419.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HwG+GLxOkelHjXj2XlVj8nAx9DE9606	rogid:0sSM4OJ+d+5uhnOI5Gp4/diGkgE632	intact-crc:D3414DABA2B9BACD|rigid:Bd+mA4PEbK8cmPucPOICVhfl71Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14222	uniprotkb:Q7CHA0	intact:EBI-724466|uniprotkb:Q59F57|uniprotkb:Q86WX7|uniprotkb:B2R6X4|ensembl:ENSP00000362305.1|ensembl:ENSP00000398568.1	intact:EBI-2861572|uniprotkb:Q74WF5	psi-mi:perf_human(display_long)|uniprotkb:Lymphocyte pore-forming protein(gene name synonym)|uniprotkb:Cytolysin(gene name synonym)|uniprotkb:PRF1(gene name)|psi-mi:PRF1(display_short)|uniprotkb:PFP(gene name synonym)	psi-mi:q7cha0_yerpe(display_long)|uniprotkb:ompC1(gene name synonym)|uniprotkb:YP_0916(locus name)|uniprotkb:y2966(locus name)|uniprotkb:ompC(gene name)|psi-mi:ompC(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861577|imex:IM-13779-6648	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:391343""|efo:""Orphanet:540""|efo:""Orphanet:88""|ensembl:ENSG00000180644.8(gene)|ensembl:ENST00000373209.2(transcript)|ensembl:ENST00000441259.2(transcript)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0001772""(immunological synapse)|go:""GO:0001913""(T cell mediated cytotoxicity)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002418""(immune response to tumor cell)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006968""(cellular defense response)|go:""GO:0009306""(protein secretion)|go:""GO:0016020""(membrane)|go:""GO:0017038""(protein import)|go:""GO:0022829""(wide pore channel activity)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031904""(endosome lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0044194""(cytolytic granule)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0051607""(defense response to virus)|go:""GO:0051712""(positive regulation of killing of cells of another organism)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0140507""(granzyme-mediated programmed cell death signaling pathway)|go:""GO:0140911""(pore-forming activity)|go:""GO:1904856""(cytolytic granule lumen)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR020863|interpro:IPR020864|interpro:IPR035892|interpro:IPR037300|interpro:IPR052784|reactome:R-HSA-9725371|refseq:NP_001076585.1|refseq:NP_005032.2|dip:DIP-53288N|panther:PTHR46096(orthology-group)"	"interpro:IPR001897(Porin, bacterial type)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR050298|interpro:IPR033900|interpro:IPR023614|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0046930""(pore complex)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EEm2Iq36E4D5zMJPDWzBXZi1KcY9606	rogid:lWS3wuw1DucPSpQ9yjzPQnjXceg632	intact-crc:E7BB0CCA23A2A706|rigid:CRBUReoPVbRdH9//arjL6nIDKvo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75381	uniprotkb:Q8D0X2	intact:EBI-594898|uniprotkb:Q8WX51|ensembl:ENSP00000349016.4|uniprotkb:B2R7N1|uniprotkb:B3KML6|uniprotkb:B7Z1N2|intact:EBI-28983483	intact:EBI-2849235	psi-mi:pex14_human(display_long)|uniprotkb:Peroxisomal membrane anchor protein PEX14(gene name synonym)|uniprotkb:PTS1 receptor-docking protein(gene name synonym)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:Peroxin-14(gene name synonym)	psi-mi:q8d0x2_yerpe(display_long)|uniprotkb:y1457(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861565|imex:IM-13779-6650	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000142655.13(gene)|ensembl:ENST00000356607.9(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0007031""(peroxisome organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016558""(protein import into peroxisome matrix)|go:""GO:0016560""(protein import into peroxisome matrix, docking)|go:""GO:0016561""(protein import into peroxisome matrix, translocation)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0036250""(peroxisome transport along microtubule)|go:""GO:0042802""(identical protein binding)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0044721""(protein import into peroxisome matrix, substrate release)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:1990429""(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|mint:O75381|rcsb pdb:2W84|rcsb pdb:2W85|rcsb pdb:4BXU|rcsb pdb:9GAG|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9603798|refseq:NP_004556.1|refseq:XP_011539882.1|efo:""Orphanet:44""|efo:""Orphanet:772""|efo:""Orphanet:912""|panther:PTHR23058(orthology-group)"	"interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR006314(Dyp-type peroxidase)|go:""GO:0004601""(peroxidase activity)|go:""GO:0020037""(heme binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR048327|interpro:IPR048328"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9RXZ+bR4fRStCHsMQihNHBhqmCo9606	rogid:6W/ykCxa45tyhuiei7YsTgIaGyU632	intact-crc:2B9CC815B3FDFED9|rigid:UTWkeWZgk9wVHU+tjzazWCUOwmw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P68590	uniprotkb:P56645	intact:EBI-2845098|uniprotkb:Q00929	intact:EBI-2827813|uniprotkb:Q9C0J3|uniprotkb:Q9UGU8|uniprotkb:Q5H8X4|uniprotkb:Q969K6|uniprotkb:Q96S77|uniprotkb:Q96S78|uniprotkb:Q9NSP9|uniprotkb:Q5H8X5|ensembl:ENSP00000355031.2	psi-mi:yopr_yerpe(display_long)|uniprotkb:yscH(gene name)|psi-mi:yscH(display_short)|uniprotkb:lcrP(gene name synonym)|uniprotkb:Yersinia outer protein R(gene name synonym)|uniprotkb:Yersinia secretion protein H(gene name synonym)|uniprotkb:yopR(gene name synonym)|uniprotkb:YPCD1.57(locus name)|uniprotkb:YP_pCD26(locus name)|uniprotkb:y0024(locus name)|uniprotkb:y5021(locus name)	psi-mi:per3_human(display_long)|uniprotkb:PER3(gene name)|psi-mi:PER3(display_short)|uniprotkb:Cell growth-inhibiting gene 13 protein(gene name synonym)|uniprotkb:Circadian clock protein PERIOD 3(gene name synonym)|uniprotkb:GIG13(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861584|imex:IM-13779-6649	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013349(Type III secretion system effector YopR)|refseq:NP_395191.1|refseq:NP_857725.1|refseq:NP_857920.1|go:""GO:0005576""(extracellular region)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|rcsb pdb:1Z21|refseq:WP_002212915.1|mint:P68590|interpro:IPR041814"	"efo:""Orphanet:164736""|ensembl:ENSG00000049246.15(gene)|ensembl:ENST00000361923.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0019900""(kinase binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0043153""(entrainment of circadian clock by photoperiod)|go:""GO:0045187""(regulation of circadian sleep/wake cycle, sleep)|go:""GO:0050821""(protein stabilization)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|interpro:IPR048814|interpro:IPR050760|mint:P56645|refseq:NP_001276790.1|refseq:NP_001276791.1|refseq:NP_001276792.1|refseq:NP_001276793.1|refseq:NP_058515.1|panther:PTHR11269(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vLBOGgil8yDmtkZgVzl8ti6IGok632	rogid:5qKr2JPd1Xbtrr7fWM/BcVaSafI9606	intact-crc:0D4FA0D473CA1F83|rigid:g5+j8uMJ2Osso8HmMlSbeYGbny4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5T2W1	uniprotkb:A0A2U2H2G1	intact:EBI-349819|uniprotkb:O60450|uniprotkb:Q5T5P6|uniprotkb:Q9BQ41|uniprotkb:B4DPB9|uniprotkb:E7EU02|ensembl:ENSP00000342143.2|ensembl:ENSP00000394485.1	intact:EBI-2857421|uniprotkb:Q74Y18|uniprotkb:Q0WKD8|uniprotkb:Q7CFV8|uniprotkb:A0A384LDE1	"psi-mi:nhrf3_human(display_long)|uniprotkb:PDZK1(gene name)|psi-mi:PDZK1(display_short)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:""Na(+)/H(+) exchanger regulatory factor 3""(gene name synonym)|uniprotkb:CAP70(gene name synonym)|uniprotkb:NHERF3(gene name synonym)|uniprotkb:PDZD1(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym)"	psi-mi:a0a2u2h2g1_yerpe(display_long)|uniprotkb:YPO0164(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861620|imex:IM-13779-6652	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188254.1|refseq:NP_002605.2|refseq:NP_001188255.1|ensembl:ENSG00000174827.14(gene)|ensembl:ENST00000344770.6(transcript)|ensembl:ENST00000417171.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005124""(scavenger receptor binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0015879""(carnitine transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0031526""(brush border membrane)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032414""(positive regulation of ion transmembrane transporter activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044070""(regulation of monoatomic anion transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:1904064""(positive regulation of cation transmembrane transport)|go:""GO:1905477""(positive regulation of protein localization to membrane)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051067|mint:Q5T2W1|rcsb pdb:2EEI|rcsb pdb:2EEJ|rcsb pdb:2VSP|rcsb pdb:3TMH|rcsb pdb:4Q2P|rcsb pdb:6EZI|refseq:XP_016856953.1|panther:PTHR14191(orthology-group)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR010100(TonB-dependent copper receptor)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|refseq:WP_002208882.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015344""(siderophore uptake transmembrane transporter activity)|go:""GO:0044718""(siderophore transmembrane transport)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002345250.1|panther:PTHR30069(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sU0SZ8m9Or0LFmLo9dh6B7RBJWs9606	rogid:OF3HwYfg6zaTqz0HTQ2WdTZ5Dv4632	intact-crc:CB20EF0DF67752CE|rigid:kJ776uEUZbVhKcYh3+PalRVKlMI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H160	uniprotkb:Q9P0J1	intact:EBI-2839804|uniprotkb:Q74VL9|uniprotkb:Q0WHA0|uniprotkb:Q7CHF5|uniprotkb:A0A384KFZ8|uniprotkb:A0A5P8YDY1	intact:EBI-2861634|uniprotkb:B3KX71|uniprotkb:Q5U5K1|uniprotkb:J3KPU0|ensembl:ENSP00000297598.4|ensembl:ENSP00000428317.1|ensembl:ENSP00000430380.1	psi-mi:a0a2u2h160_yerpe(display_long)|uniprotkb:YPO1313(locus name)	psi-mi:pdp1_human(display_long)|uniprotkb:PDP1(gene name)|psi-mi:PDP1(display_short)|uniprotkb:PDP(gene name synonym)|uniprotkb:PPM2C(gene name synonym)|uniprotkb:Protein phosphatase 2C(gene name synonym)|uniprotkb:Pyruvate dehydrogenase phosphatase catalytic subunit 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861640|imex:IM-13779-6653	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|refseq:WP_002208782.1|interpro:IPR010916(TonB box, conserved site)|go:""GO:0009279""(cell outer membrane)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002346338.1"	"ensembl:ENSG00000164951.16(gene)|ensembl:ENST00000297598.5(transcript)|ensembl:ENST00000517764.1(transcript)|ensembl:ENST00000520728.5(transcript)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0004741""(""[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity"")|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0007165""(signal transduction)|go:""GO:0035970""(peptidyl-threonine dephosphorylation)|go:""GO:0045253""(""pyruvate dehydrogenase (lipoamide) phosphatase complex"")|go:""GO:0046872""(metal ion binding)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q9P0J1|reactome:R-HSA-204174|refseq:NP_001155251.1|refseq:NP_001155252.1|refseq:NP_001155253.1|refseq:NP_060914.2|refseq:XP_011515438.1|efo:""Orphanet:79246""|panther:PTHR13832(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Mg0owqCn0ozvLrRu4vW8Rgc4sZk632	rogid:IXJq+qtJ0oAoODs/pXB1/NehhRY9606	intact-crc:F8E9219CEF398E90|rigid:hT5Si1CeYtP3DKsD/QUUH5Zt4S0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG7	uniprotkb:Q6P996	intact:EBI-2843887|uniprotkb:Q0WIB0	intact:EBI-1049813|uniprotkb:Q4F6X7|uniprotkb:O00236|uniprotkb:Q6PID7|uniprotkb:Q86YF1|uniprotkb:Q8N4Q9|uniprotkb:Q8TBS5|ensembl:ENSP00000379691.4|ensembl:ENSP00000484595.1|uniprotkb:B4DR55|uniprotkb:B4DSL3|uniprotkb:E7EMH5|uniprotkb:E7EPL4|uniprotkb:H3BNZ1|intact:EBI-10982185	psi-mi:metk_yerpe(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:MAT(gene name synonym)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:YPO0931(locus name)|uniprotkb:y3314(locus name)|uniprotkb:YP_3512(locus name)	psi-mi:pdxd1_human(display_long)|uniprotkb:PDXDC1(gene name)|psi-mi:PDXDC1(display_short)|uniprotkb:KIAA0251(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861627|imex:IM-13779-6655	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|refseq:WP_002209971.1|refseq:YP_002345978.1|panther:PTHR11964(orthology-group)"	"refseq:NP_001272373.1|refseq:NP_001272374.1|refseq:NP_001272376.1|refseq:NP_001272377.1|refseq:NP_001272379.1|refseq:NP_055842.2|refseq:XP_006725291.1|refseq:XP_006726663.1|refseq:XP_006725288.1|refseq:XP_006726660.1|ensembl:ENSG00000179889.21(gene)|ensembl:ENSG00000275498.5(gene)|ensembl:ENST00000396410.9(transcript)|ensembl:ENST00000618389.4(transcript)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0016831""(carboxy-lyase activity)|go:""GO:0019752""(carboxylic acid metabolic process)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR050477|interpro:IPR055102|interpro:IPR055103|mint:Q6P996|panther:PTHR42735(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1htJOEwkQpME5HLtvSLlZmF2H0s632	rogid:59DMMTVwe8bQCfqtUSZcV+nhEDQ9606	intact-crc:EE7D9D74822A9BDC|rigid:jvADFPU//u6etDfEL2j7OMJJw9Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H4H5	uniprotkb:Q9NR12	intact:EBI-2840718|uniprotkb:Q74QU3|uniprotkb:A0A384KBL5|uniprotkb:A0A0H2W7L1|uniprotkb:Q7CG19	intact:EBI-350517|uniprotkb:Q14250|uniprotkb:Q5XG82|uniprotkb:Q6NVZ5|uniprotkb:Q96C91|uniprotkb:Q9BXB8|uniprotkb:Q9BXB9|intact:EBI-2556830|ensembl:ENSP00000348099.2	psi-mi:a0a2u2h4h5_yerpe(display_long)|uniprotkb:dppB(gene name)|psi-mi:dppB(display_short)|uniprotkb:ISU56_01415(orf name)|uniprotkb:ISU59_01410(orf name)|uniprotkb:YPO4002(locus name)	psi-mi:pdli7_human(display_long)|uniprotkb:LIM mineralization protein(gene name synonym)|uniprotkb:Protein enigma(gene name synonym)|uniprotkb:PDLIM7(gene name)|psi-mi:PDLIM7(display_short)|uniprotkb:ENIGMA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861647|imex:IM-13779-6654	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:YP_002348870.1|go:""GO:0005886""(plasma membrane)|go:""GO:0071916""(dipeptide transmembrane transporter activity)|interpro:IPR035906|interpro:IPR045621|panther:PTHR43163(orthology-group)"	"refseq:NP_976227.1|refseq:NP_998801.1|refseq:NP_005442.2|ensembl:ENSG00000196923.14(gene)|ensembl:ENST00000355841.7(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007507""(heart development)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030154""(cell differentiation)|go:""GO:0031941""(filamentous actin)|go:""GO:0046872""(metal ion binding)|go:""GO:0051371""(muscle alpha-actinin binding)|go:""GO:0061061""(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036034|interpro:IPR050604|mint:Q9NR12|rcsb pdb:2Q3G|rcsb pdb:7RM8|reactome:R-HSA-8853659|panther:PTHR24214(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t6DtAXJvQYdpOXJQ03y6RzwNH6w632	rogid:XBVF0Y1DFqIYbnt/e/rYqS/m4d09606	intact-crc:78DD55E0680B3F76|rigid:6+tqrE/3SajBUn0ONC0FmrK31bA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5T2W1	uniprotkb:Q8ZJN2	intact:EBI-349819|uniprotkb:O60450|uniprotkb:Q5T5P6|uniprotkb:Q9BQ41|uniprotkb:B4DPB9|uniprotkb:E7EU02|ensembl:ENSP00000342143.2|ensembl:ENSP00000394485.1	intact:EBI-2861608|uniprotkb:Q0WKN2	"psi-mi:nhrf3_human(display_long)|uniprotkb:PDZK1(gene name)|psi-mi:PDZK1(display_short)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:""Na(+)/H(+) exchanger regulatory factor 3""(gene name synonym)|uniprotkb:CAP70(gene name synonym)|uniprotkb:NHERF3(gene name synonym)|uniprotkb:PDZD1(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym)"	psi-mi:tdh_yerpe(display_long)|uniprotkb:tdh(gene name)|psi-mi:tdh(display_short)|uniprotkb:YPO0060(locus name)|uniprotkb:y0080(locus name)|uniprotkb:YP_0061(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861613|imex:IM-13779-6656	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188254.1|refseq:NP_002605.2|refseq:NP_001188255.1|ensembl:ENSG00000174827.14(gene)|ensembl:ENST00000344770.6(transcript)|ensembl:ENST00000417171.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005124""(scavenger receptor binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0015879""(carnitine transport)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0031526""(brush border membrane)|go:""GO:0031528""(microvillus membrane)|go:""GO:0032414""(positive regulation of ion transmembrane transporter activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044070""(regulation of monoatomic anion transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:1904064""(positive regulation of cation transmembrane transport)|go:""GO:1905477""(positive regulation of protein localization to membrane)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR051067|mint:Q5T2W1|rcsb pdb:2EEI|rcsb pdb:2EEJ|rcsb pdb:2VSP|rcsb pdb:3TMH|rcsb pdb:4Q2P|rcsb pdb:6EZI|refseq:XP_016856953.1|panther:PTHR14191(orthology-group)"	"interpro:IPR020843|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR004627(L-threonine 3-dehydrogenase)|refseq:WP_002208981.1|interpro:IPR050129|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008743""(L-threonine 3-dehydrogenase activity)|go:""GO:0019518""(L-threonine catabolic process to glycine)|interpro:IPR036291|refseq:YP_002345156.1|panther:PTHR43401(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sU0SZ8m9Or0LFmLo9dh6B7RBJWs9606	rogid:2WjdVfkVkq+pdNJ3zOcAd8D8Ywk632	intact-crc:7FBF7CCAFEC3F878|rigid:UakxobF0r3rCfTC30vMy5YugU5I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00151	uniprotkb:A0A5P8YGH0	intact:EBI-724897|uniprotkb:Q5VZH5|uniprotkb:Q9BPZ9|uniprotkb:B2RBS6|ensembl:ENSP00000360305.3	intact:EBI-2861664|uniprotkb:Q0WGY5|uniprotkb:Q7CHL3|uniprotkb:A0A384LDW6	psi-mi:pdli1_human(display_long)|uniprotkb:Elfin(gene name synonym)|uniprotkb:LIM domain protein CLP-36(gene name synonym)|uniprotkb:C-terminal LIM domain protein 1(gene name synonym)|uniprotkb:PDLIM1(gene name)|psi-mi:PDLIM1(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:CLP36(gene name synonym)	psi-mi:a0a5p8ygh0_yerpe(display_long)|uniprotkb:YPO1431(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861661|imex:IM-13779-6660	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066272.1|ensembl:ENSG00000107438.9(gene)|ensembl:ENST00000329399.7(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001725""(stress fiber)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003779""(actin binding)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007507""(heart development)|go:""GO:0010761""(fibroblast migration)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030950""(establishment or maintenance of actin cytoskeleton polarity)|go:""GO:0031941""(filamentous actin)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0051371""(muscle alpha-actinin binding)|go:""GO:0061061""(muscle structure development)|go:""GO:0098641""(cadherin binding involved in cell-cell adhesion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR028537|interpro:IPR031847|interpro:IPR036034|interpro:IPR050604|mint:O00151|rcsb pdb:1X62|rcsb pdb:2PKT|panther:PTHR24214(orthology-group)"	"interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR020568|interpro:IPR027417|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR027065|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006508""(proteolysis)|go:""GO:0030163""(protein catabolic process)|interpro:IPR041699|refseq:YP_002346453.1|panther:PTHR10046(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kUUqX2NgmaXbdbESj6oHxE+EQ2g9606	rogid:fL4BVzBvolyBNezgz2VmOlRMsMA632	intact-crc:5F58FF95D0370764|rigid:/dqX0YrVqGyX+fP4g4MuV2GLnBQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BY77	uniprotkb:A0A3N4B749	intact:EBI-1776152|uniprotkb:Q5H972|uniprotkb:Q6PGN6|uniprotkb:Q7Z6Z0|uniprotkb:Q9NSP5|uniprotkb:Q9NSP6|uniprotkb:A8K6F8|uniprotkb:A8K6V9|uniprotkb:Q009A7|ensembl:ENSP00000252115.5	intact:EBI-2842996|uniprotkb:Q74V98|uniprotkb:Q0WGP3|uniprotkb:Q7CHR5|uniprotkb:A0A384LAC1	psi-mi:pdip3_human(display_long)|uniprotkb:POLDIP3(gene name)|psi-mi:POLDIP3(display_short)|uniprotkb:KIAA1649(gene name synonym)|uniprotkb:PDIP46(gene name synonym)|uniprotkb:46 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:S6K1 Aly/REF-like target(gene name synonym)	psi-mi:a0a3n4b749_yerpe(display_long)|uniprotkb:YPO1529(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861682|imex:IM-13779-6659	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115687.2|refseq:NP_835237.1|ensembl:ENSG00000100227.19(gene)|ensembl:ENST00000252115.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016607""(nuclear speck)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045727""(positive regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034784|interpro:IPR035979|interpro:IPR051229|mint:Q9BY77|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|panther:PTHR19965(orthology-group)"	"interpro:IPR010977(Aromatic-L-amino-acid decarboxylase)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002211877.1|go:""GO:0005737""(cytoplasm)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0016831""(carboxy-lyase activity)|go:""GO:0019752""(carboxylic acid metabolic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:YP_002346545.1|panther:PTHR45677(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:64+Bf4QpCDdKkZMMH/7afOnOKH09606	rogid:Uex6pAvRG3FNG1VCbilPXw5bliY632	intact-crc:2C6BF94546C9BFA6|rigid:kkVDp6uF5Om9HFcCGN3k79XLWro	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16654	uniprotkb:Q8D0V8	intact:EBI-2861674|ensembl:ENSP00000005178.5	intact:EBI-2843099	psi-mi:pdk4_human(display_long)|uniprotkb:PDK4(gene name)|psi-mi:PDK4(display_short)|uniprotkb:PDHK4(gene name synonym)|uniprotkb:Pyruvate dehydrogenase kinase isoform 4(gene name synonym)	psi-mi:q8d0v8_yerpe(display_long)|uniprotkb:y1519(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861671|imex:IM-13779-6658	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002603.1|ensembl:ENSG00000004799.8(gene)|ensembl:ENST00000005178.6(transcript)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004740""(""pyruvate dehydrogenase (acetyl-transferring) kinase activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006885""(regulation of pH)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010510""(regulation of acetyl-CoA biosynthetic process from pyruvate)|go:""GO:0010565""(regulation of ketone metabolic process)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0042304""(regulation of fatty acid biosynthetic process)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042594""(response to starvation)|go:""GO:0045124""(regulation of bone resorption)|go:""GO:0046320""(regulation of fatty acid oxidation)|go:""GO:0071398""(cellular response to fatty acid)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|rcsb pdb:2E0A|rcsb pdb:2ZDX|rcsb pdb:2ZDY|rcsb pdb:2ZKJ|rcsb pdb:3D2R|rcsb pdb:7EAT|rcsb pdb:7EBB|rcsb pdb:7EBG|reactome:R-HSA-204174|reactome:R-HSA-5362517|reactome:R-HSA-9841922|panther:PTHR11947(orthology-group)"	"interpro:IPR011888(Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR019546|interpro:IPR027467|go:""GO:0009389""(dimethyl sulfoxide reductase activity)|go:""GO:0030151""(molybdenum ion binding)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR050612"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xAjJT16weTv1tdBqXnYGX/sfb8E9606	rogid:CcHr0E9LratmjBgXeGfmzvxLVPo632	intact-crc:0AFD6893C2FED247|rigid:ElDlavuJgpFzqInpOl7sxjz8eLo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D008	uniprotkb:P30101	intact:EBI-2841189|uniprotkb:Q74WC8	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289.5	psi-mi:q8d008_yerpe(display_long)|uniprotkb:livM2(gene name)|psi-mi:livM2(display_short)|uniprotkb:YP_0948(locus name)|uniprotkb:y3001(locus name)	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861689|imex:IM-13779-6661	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|interpro:IPR017779(ABC transporter, urea, permease protein, UrtB)|interpro:IPR016024(Armadillo-type fold)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR052157"	"ensembl:ENSG00000167004.14(gene)|ensembl:ENST00000300289.10(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004629""(phospholipase C activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0009986""(cell surface)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061779""(Tapasin-ERp57 complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|rcsb pdb:7QNG|rcsb pdb:7QPD|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|refseq:NP_005304.3|dip:DIP-29132N|panther:PTHR18929(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:f8uYuwhgruoNpYu1MdwJpc91v5Q632	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	intact-crc:72E2BAF6A6AC6910|rigid:ZQu0ZqA2K4PyYae5zxm1Yt1/Iug	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NR12	uniprotkb:Q8ZAN0	intact:EBI-350517|uniprotkb:Q14250|uniprotkb:Q5XG82|uniprotkb:Q6NVZ5|uniprotkb:Q96C91|uniprotkb:Q9BXB8|uniprotkb:Q9BXB9|intact:EBI-2556830|ensembl:ENSP00000348099.2	intact:EBI-2842242|uniprotkb:Q0WAP3	psi-mi:pdli7_human(display_long)|uniprotkb:LIM mineralization protein(gene name synonym)|uniprotkb:Protein enigma(gene name synonym)|uniprotkb:PDLIM7(gene name)|psi-mi:PDLIM7(display_short)|uniprotkb:ENIGMA(gene name synonym)	psi-mi:fadb_yerpe(display_long)|uniprotkb:fadB(gene name)|psi-mi:fadB(display_short)|uniprotkb:YPO3766(locus name)|uniprotkb:y0464(locus name)|uniprotkb:YP_3282(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861654|imex:IM-13779-6657	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_976227.1|refseq:NP_998801.1|refseq:NP_005442.2|ensembl:ENSG00000196923.14(gene)|ensembl:ENST00000355841.7(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0003779""(actin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007507""(heart development)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030154""(cell differentiation)|go:""GO:0031941""(filamentous actin)|go:""GO:0046872""(metal ion binding)|go:""GO:0051371""(muscle alpha-actinin binding)|go:""GO:0061061""(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036034|interpro:IPR050604|mint:Q9NR12|rcsb pdb:2Q3G|rcsb pdb:7RM8|reactome:R-HSA-8853659|panther:PTHR24214(orthology-group)"	"interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|interpro:IPR012799(Fatty oxidation complex, alpha subunit FadB)|interpro:IPR029045|go:""GO:0004165""(""delta(3)-delta(2)-enoyl-CoA isomerase activity"")|go:""GO:0004300""(enoyl-CoA hydratase activity)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0008692""(3-hydroxybutyryl-CoA epimerase activity)|go:""GO:0016509""(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0036125""(fatty acid beta-oxidation multienzyme complex)|go:""GO:0070403""(NAD+ binding)|refseq:WP_002211546.1|interpro:IPR036291|refseq:YP_002348645.1|interpro:IPR050136|panther:PTHR43612(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XBVF0Y1DFqIYbnt/e/rYqS/m4d09606	rogid:zUCGFSdEv7X+WT+PNMNgwgSM+4c632	intact-crc:D393F6180AF09A90|rigid:TSG7BkQcj/gxezVHl5/61W3h2YY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08499	uniprotkb:Q8D0R7	intact:EBI-1642831|uniprotkb:Q13550|uniprotkb:O43433|uniprotkb:Q13549|uniprotkb:Q13551|uniprotkb:Q7Z2L8|uniprotkb:Q8IV84|uniprotkb:Q8IVA9|uniprotkb:Q8IVD2|uniprotkb:Q8IVD3|uniprotkb:Q96HL4|uniprotkb:Q9HCX7|ensembl:ENSP00000345502.6	intact:EBI-2851663	psi-mi:pde4d_human(display_long)|uniprotkb:PDE4D(gene name)|psi-mi:PDE4D(display_short)|uniprotkb:DPDE3(gene name synonym)|uniprotkb:PDE43(gene name synonym)|uniprotkb:cAMP-specific phosphodiesterase 4D(gene name synonym)	psi-mi:q8d0r7_yerpe(display_long)|uniprotkb:y1701(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861717|imex:IM-13779-6663	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-41115N|ensembl:ENSG00000113448.21(gene)|ensembl:ENST00000340635.11(transcript)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0004114""(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:""GO:0004115""(3',5'-cyclic-AMP phosphodiesterase activity)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005891""(voltage-gated calcium channel complex)|go:""GO:0006198""(cAMP catabolic process)|go:""GO:0010460""(positive regulation of heart rate)|go:""GO:0010880""(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019933""(cAMP-mediated signaling)|go:""GO:0030545""(signaling receptor regulator activity)|go:""GO:0030552""(cAMP binding)|go:""GO:0031698""(beta-2 adrenergic receptor binding)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0032754""(positive regulation of interleukin-5 production)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0034704""(calcium channel complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045822""(negative regulation of heart contraction)|go:""GO:0046872""(metal ion binding)|go:""GO:0047555""(3',5'-cyclic-GMP phosphodiesterase activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051117""(ATPase binding)|go:""GO:0061028""(establishment of endothelial barrier)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0071872""(cellular response to epinephrine stimulus)|go:""GO:0071875""(adrenergic receptor signaling pathway)|rcsb pdb:1XOM|go:""GO:0086004""(regulation of cardiac muscle cell contraction)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0106072""(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:1901363""(heterocyclic compound binding)|go:""GO:1901844""(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:""GO:1901898""(negative regulation of relaxation of cardiac muscle)|go:""GO:1902514""(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR023088|interpro:IPR023174|interpro:IPR036971|interpro:IPR040844|mint:Q08499|rcsb pdb:1E9K|rcsb pdb:1MKD|rcsb pdb:1OYN|rcsb pdb:1PTW|rcsb pdb:1Q9M|rcsb pdb:1TB7|rcsb pdb:1TBB|rcsb pdb:1XON|rcsb pdb:1XOQ|rcsb pdb:1XOR|rcsb pdb:1Y2B|rcsb pdb:1Y2C|rcsb pdb:1Y2D|rcsb pdb:1Y2E|rcsb pdb:1Y2K|rcsb pdb:1ZKN|rcsb pdb:2FM0|rcsb pdb:2FM5|rcsb pdb:2PW3|rcsb pdb:2QYN|rcsb pdb:3G4G|rcsb pdb:3G4I|rcsb pdb:3G4K|rcsb pdb:3G4L|rcsb pdb:3G58|rcsb pdb:3IAD|rcsb pdb:3IAK|rcsb pdb:3K4S|rcsb pdb:3SL3|rcsb pdb:3SL4|rcsb pdb:3SL5|rcsb pdb:3SL6|rcsb pdb:3SL8|rcsb pdb:3V9B|rcsb pdb:4OGB|rcsb pdb:4W1O|rcsb pdb:4WCU|rcsb pdb:5K1I|rcsb pdb:5K32|rcsb pdb:5LBO|rcsb pdb:5TKB|rcsb pdb:5WH5|rcsb pdb:5WH6|rcsb pdb:5WQA|rcsb pdb:6AKR|rcsb pdb:6BOJ|rcsb pdb:6F6U|rcsb pdb:6F8R|rcsb pdb:6F8T|rcsb pdb:6F8U|rcsb pdb:6F8V|rcsb pdb:6F8W|rcsb pdb:6F8X|rcsb pdb:6FDC|rcsb pdb:6FDI|rcsb pdb:6FE7|rcsb pdb:6FEB|rcsb pdb:6FET|rcsb pdb:6FT0|rcsb pdb:6FTA|rcsb pdb:6FTW|rcsb pdb:6FW3|rcsb pdb:6HWO|rcsb pdb:6IAG|rcsb pdb:6IBF|rcsb pdb:6IM6|rcsb pdb:6IMB|rcsb pdb:6IMD|rcsb pdb:6IMI|rcsb pdb:6IMO|rcsb pdb:6IMR|rcsb pdb:6IMT|rcsb pdb:6IND|rcsb pdb:6INK|rcsb pdb:6INM|rcsb pdb:6KJZ|rcsb pdb:6KK0|rcsb pdb:6LRM|rcsb pdb:6NJH|rcsb pdb:6NJI|rcsb pdb:6NJJ|rcsb pdb:6RCW|rcsb pdb:6ZBA|rcsb pdb:7A8Q|rcsb pdb:7A9V|rcsb pdb:7AAG|rcsb pdb:7AB9|rcsb pdb:7ABD|rcsb pdb:7ABE|rcsb pdb:7ABJ|rcsb pdb:7AY6|rcsb pdb:7B9H|rcsb pdb:7CBJ|rcsb pdb:7CBQ|rcsb pdb:7F2K|rcsb pdb:7F2L|rcsb pdb:7F2M|rcsb pdb:7W4X|rcsb pdb:7W4Y|rcsb pdb:7XAA|rcsb pdb:7XAB|rcsb pdb:7XBB|rcsb pdb:7YQF|rcsb pdb:7YSX|rcsb pdb:8K4C|rcsb pdb:8K4H|rcsb pdb:8W4Q|rcsb pdb:8W4R|rcsb pdb:8WDN|rcsb pdb:8WDO|rcsb pdb:8YLC|reactome:R-HSA-180024|reactome:R-HSA-418555|reactome:R-HSA-9860927|refseq:NP_001098101.1|refseq:NP_001159371.1|refseq:NP_001184147.1|refseq:NP_001184148.1|refseq:NP_001184149.1|refseq:NP_001184150.1|refseq:NP_001184151.1|refseq:NP_001184152.1|refseq:NP_006194.2|refseq:XP_005248595.1|refseq:XP_011541773.1|refseq:XP_011541775.1|refseq:XP_016865055.1|efo:""Orphanet:439822""|efo:""Orphanet:950""|panther:PTHR11347(orthology-group)"	"interpro:IPR006914(Protein of unknown function DUF638, haemagglutinin/haemolysin putative)|go:""GO:0090729""(toxin activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Vt17V/Avstf55ZLmURcuv+JcJYA9606	rogid:Ks3lO/T2b4EUIIi1eSL1nvjMQjw632	intact-crc:9D5BEA109D95B33D|rigid:Wo7+gY3a/fF9fML/gABTYtZKwAw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYH3	uniprotkb:P30101	intact:EBI-2842340|uniprotkb:Q74PE3|uniprotkb:Q0W9X2|uniprotkb:Q7CFQ3|uniprotkb:A0A5P8YAI4|uniprotkb:A0A384L096	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289.5	psi-mi:a0a2u2gyh3_yerpe(display_long)|uniprotkb:fdoH(gene name)|psi-mi:fdoH(display_short)|uniprotkb:YPO4057(locus name)	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861696|imex:IM-13779-6666	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR006470(Formate dehydrogenase, beta subunit)|interpro:IPR014603(Formate dehydrogenase, iron-sulphur subunit)|interpro:IPR015246(Formate dehydrogenase, transmembrane)|interpro:IPR017900|go:""GO:0005886""(plasma membrane)|go:""GO:0015944""(formate oxidation)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002209611.1|interpro:IPR038384|refseq:YP_002348916.1|interpro:IPR051555"	"ensembl:ENSG00000167004.14(gene)|ensembl:ENST00000300289.10(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004629""(phospholipase C activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0009986""(cell surface)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061779""(Tapasin-ERp57 complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|rcsb pdb:7QNG|rcsb pdb:7QPD|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|refseq:NP_005304.3|dip:DIP-29132N|panther:PTHR18929(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:qUnsGukyBMEHq2jL5PYOvQ0betE632	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	intact-crc:0DE601D356F3A65B|rigid:5mCFXkrVb5/+SDXiBqy18iKBpak	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30101	uniprotkb:P40127	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289.5	intact:EBI-2844091|uniprotkb:Q0WAG2	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	psi-mi:cyaa_yerpe(display_long)|uniprotkb:cya(gene name)|psi-mi:cya(display_short)|uniprotkb:cyaA(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:YPO3848(locus name)|uniprotkb:y0382(locus name)|uniprotkb:YP_3199(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861710|imex:IM-13779-6665	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000167004.14(gene)|ensembl:ENST00000300289.10(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004629""(phospholipase C activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0009986""(cell surface)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061779""(Tapasin-ERp57 complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|rcsb pdb:7QNG|rcsb pdb:7QPD|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|refseq:NP_005304.3|dip:DIP-29132N|panther:PTHR18929(orthology-group)"	"interpro:IPR000274(Adenylate cyclase, class-I)|interpro:IPR024686|interpro:IPR024685|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006171""(cAMP biosynthetic process)|refseq:WP_002211468.1|refseq:YP_002348726.1|panther:PTHR38760(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	rogid:l0RzY0/qkJ4UmTdMusK/+DQB0ow632	intact-crc:0FB18C2C34ACD704|rigid:qzl+JqlqAuDbGxKO/eisszarETw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O68723	uniprotkb:P30101	intact:EBI-2857889|uniprotkb:Q74YR2	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289.5	psi-mi:o68723_yerpe(display_long)|uniprotkb:Y1050(locus name)|uniprotkb:YP_pMT006(locus name)|uniprotkb:ORF90(gene name)|psi-mi:ORF90(display_short)	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861703|imex:IM-13779-6662	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR025484	"ensembl:ENSG00000167004.14(gene)|ensembl:ENST00000300289.10(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004197""(cysteine-type endopeptidase activity)|go:""GO:0004629""(phospholipase C activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0009986""(cell surface)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0061779""(Tapasin-ERp57 complex)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|rcsb pdb:7QNG|rcsb pdb:7QPD|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|refseq:NP_005304.3|dip:DIP-29132N|panther:PTHR18929(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:OZFkxl3As03E0sa5pPXdevNZfhM632	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	intact-crc:3F04BDA7F9102B29|rigid:lAmPFSKI0LNEwdLcwU1280LZyzo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:O00408	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-1785967|ensembl:ENSP00000334910.5|uniprotkb:B2R646|uniprotkb:B3KRV5|uniprotkb:Q5J791|uniprotkb:Q5J792|uniprotkb:Q6ZMR1|uniprotkb:E9PGI1|uniprotkb:Q5J793|uniprotkb:F6W5Z0	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:pde2a_human(display_long)|uniprotkb:PDE2A(gene name)|psi-mi:PDE2A(display_short)|uniprotkb:Cyclic GMP-stimulated phosphodiesterase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861724|imex:IM-13779-6664	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"ensembl:ENSG00000186642.16(gene)|ensembl:ENST00000334456.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003170""(heart valve development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0004115""(3',5'-cyclic-AMP phosphodiesterase activity)|go:""GO:0004118""(3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity)|go:""GO:0004119""(3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010752""(regulation of cGMP-mediated signaling)|go:""GO:0010754""(negative regulation of cGMP-mediated signaling)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0019933""(cAMP-mediated signaling)|go:""GO:0019934""(cGMP-mediated signaling)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0030552""(cAMP binding)|go:""GO:0030553""(cGMP binding)|go:""GO:0030911""(TPR domain binding)|go:""GO:0035904""(aorta development)|go:""GO:0036006""(cellular response to macrophage colony-stimulating factor stimulus)|go:""GO:0042301""(phosphate ion binding)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043116""(negative regulation of vascular permeability)|go:""GO:0043117""(positive regulation of vascular permeability)|go:""GO:0043951""(negative regulation of cAMP-mediated signaling)|go:""GO:0046069""(cGMP catabolic process)|go:""GO:0047555""(3',5'-cyclic-GMP phosphodiesterase activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0061028""(establishment of endothelial barrier)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0071321""(cellular response to cGMP)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0097011""(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:""GO:0097060""(synaptic membrane)|go:""GO:0106072""(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:1904613""(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003018(GAF)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|interpro:IPR023174|interpro:IPR029016|interpro:IPR036971|rcsb pdb:1Z1L|rcsb pdb:3IBJ|rcsb pdb:3ITM|rcsb pdb:3ITU|rcsb pdb:5TZC|rcsb pdb:4C1I|rcsb pdb:4D08|rcsb pdb:4D09|rcsb pdb:4HTX|rcsb pdb:4HTZ|rcsb pdb:4JIB|rcsb pdb:5TZ3|rcsb pdb:5TZA|rcsb pdb:5TZH|rcsb pdb:5TZW|rcsb pdb:5TZX|rcsb pdb:5TZZ|rcsb pdb:5U00|rcsb pdb:5U7D|rcsb pdb:5U7I|rcsb pdb:5U7J|rcsb pdb:5U7K|rcsb pdb:5U7L|rcsb pdb:5VP0|rcsb pdb:5VP1|rcsb pdb:5XKM|rcsb pdb:6B96|rcsb pdb:6B97|rcsb pdb:6B98|rcsb pdb:6BLF|rcsb pdb:6C7D|rcsb pdb:6C7E|rcsb pdb:6C7F|rcsb pdb:6C7G|rcsb pdb:6C7I|rcsb pdb:6C7J|rcsb pdb:6CYB|rcsb pdb:6CYC|rcsb pdb:6CYD|rcsb pdb:6ZND|rcsb pdb:6ZQZ|reactome:R-HSA-418457|reactome:R-HSA-418555|refseq:NP_001137311.1|refseq:NP_001139681.1|refseq:NP_001230713.1|refseq:NP_002590.1|dip:DIP-40269N|efo:""Orphanet:31709""|panther:PTHR11347(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:vKnWkyeXHri0mNGezTw14HQyl6E9606	intact-crc:8106527877E03F03|rigid:CK3XYaVs2SKgK8dyc3SKN6FB7I0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O68769	uniprotkb:O14737	intact:EBI-2845621|uniprotkb:A0A384LBJ7|uniprotkb:Q74YJ8|uniprotkb:Q7ARC7|uniprotkb:Q7BT03|uniprotkb:A0A3G5LHP7|uniprotkb:A0A1U8QJV7|uniprotkb:A0A2U2H212	intact:EBI-712290|uniprotkb:Q53YC9|uniprotkb:Q6IB70|ensembl:ENSP00000466214.1|uniprotkb:B4DE64	psi-mi:o68769_yerpe(display_long)|uniprotkb:YPMT1.55c(locus name)	psi-mi:pdcd5_human(display_long)|uniprotkb:TF-1 cell apoptosis-related protein 19(gene name synonym)|uniprotkb:PDCD5(gene name)|psi-mi:PDCD5(display_short)|uniprotkb:TFAR19(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861757|imex:IM-13779-6669	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395400.1|refseq:YP_093945.1|refseq:NP_857688.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|refseq:WP_002213143.1"	"refseq:NP_004699.1|ensembl:ENSG00000105185.12(gene)|ensembl:ENST00000590247.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008201""(heparin binding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010698""(acetyltransferase activator activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:1903645""(negative regulation of chaperone-mediated protein folding)|interpro:IPR002836(DNA-binding TFAR19-related protein)|interpro:IPR036883|mint:O14737|rcsb pdb:1YYB|rcsb pdb:2CRU|rcsb pdb:2K6B|refseq:XP_005259449.1|dip:DIP-50602N|panther:PTHR10840(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:nQbvf/FMyfPAI9dWsYFXKmJ70HI632	rogid:K2DZzTWT7H8gGATfyR72aXDu5qc9606	intact-crc:4235ED7404126D04|rigid:A+pBrAoHewWPZxi84OEIoxaHzf4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WUM4	uniprotkb:Q7ARD3	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|ensembl:ENSP00000307387.3|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|intact:EBI-28983290|uniprotkb:C5MQH7|intact:EBI-10971645	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861764|imex:IM-13779-6671	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037506.2|ensembl:ENSG00000170248.15(gene)|ensembl:ENST00000307296.8(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0000915""(actomyosin contractile ring assembly)|go:""GO:0001772""(immunological synapse)|go:""GO:0005768""(endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006915""(apoptotic process)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0031871""(proteinase activated receptor binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0042470""(melanosome)|go:""GO:0042641""(actomyosin)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045199""(maintenance of epithelial cell apical/basal polarity)|go:""GO:0046755""(viral budding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0061952""(midbody abscission)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090543""(Flemming body)|go:""GO:0090559""(regulation of membrane permeability)|go:""GO:0090611""(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0097734""(extracellular exosome biogenesis)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903551""(regulation of extracellular exosome assembly)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001155901.1|refseq:NP_001243121.1|dip:DIP-29327N|panther:PTHR23030(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:467D4CDAFC322E91|rigid:mM53PukKsRRhh+75o3u9C/0iq0E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZI65	uniprotkb:O75340	intact:EBI-2861734|uniprotkb:Q0WJ21	intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933.4	psi-mi:uppp_yerpe(display_long)|uniprotkb:uppP(gene name)|psi-mi:uppP(display_short)|uniprotkb:bacA(gene name synonym)|uniprotkb:upk(gene name synonym)|uniprotkb:Bacitracin resistance protein(gene name synonym)|uniprotkb:Undecaprenyl pyrophosphate phosphatase(gene name synonym)|uniprotkb:YPO0649(locus name)|uniprotkb:y3530(locus name)|uniprotkb:YP_2964(locus name)	psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861731|imex:IM-13779-6667	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003824(Bacitracin resistance protein BacA)|refseq:WP_002212198.1|go:""GO:0005886""(plasma membrane)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0046677""(response to antibiotic)|go:""GO:0050380""(undecaprenyl-diphosphatase activity)|go:""GO:0071555""(cell wall organization)|refseq:YP_002345717.1|panther:PTHR30622(orthology-group)"	"refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915.9(gene)|ensembl:ENST00000264933.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0014029""(neural crest formation)|go:""GO:0014032""(neural crest cell development)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0034605""(cellular response to heat)|go:""GO:0036324""(vascular endothelial growth factor receptor-2 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:1902527""(positive regulation of protein monoubiquitination)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR051426|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|dip:DIP-33217N|panther:PTHR46212(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:r1pysucSjBzjeuzCD1OtdzE/AI0632	rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606	intact-crc:6B834FE6B1ED9CE3|rigid:kq3kzwxPQ4tsq+e/P2vnNqaiZCc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75340	uniprotkb:Q8CZP1	intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933.4	intact:EBI-2841780|uniprotkb:Q74PZ9	psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym)	psi-mi:q8czp1_yerpe(display_long)|uniprotkb:slt(gene name)|psi-mi:slt(display_short)|uniprotkb:y3727(locus name)|uniprotkb:YP_3731(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861743|imex:IM-13779-6670	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915.9(gene)|ensembl:ENST00000264933.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0014029""(neural crest formation)|go:""GO:0014032""(neural crest cell development)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0034605""(cellular response to heat)|go:""GO:0036324""(vascular endothelial growth factor receptor-2 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:1902527""(positive regulation of protein monoubiquitination)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR051426|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|dip:DIP-33217N|panther:PTHR46212(orthology-group)"	"interpro:IPR023346|interpro:IPR008258(Lytic transglycosylase-like, catalytic)|interpro:IPR012289(Lytic transglycosylase, superhelical linker)|interpro:IPR000189(Prokaryotic transglycosylase, active site)|go:""GO:0000270""(peptidoglycan metabolic process)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0008933""(peptidoglycan lytic transglycosylase activity)|go:""GO:0016020""(membrane)|go:""GO:0042597""(periplasmic space)|go:""GO:0071555""(cell wall organization)|interpro:IPR008939(Lytic transglycosylase, superhelical U-shaped)|interpro:IPR037061"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606	rogid:Pmviwr1VF0ZHZlL9P5QBIiIIaI8632	intact-crc:670E2D0FB08891F6|rigid:e/3uECtPI2nOT2+dW2kqlALDgSg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75340	uniprotkb:Q8D0P1	intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933.4	intact:EBI-2856506|uniprotkb:Q8ZFL9|uniprotkb:Q0WGA3	psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym)	psi-mi:chey_yerpe(display_long)|uniprotkb:cheY(gene name)|psi-mi:cheY(display_short)|uniprotkb:YPO1680(locus name)|uniprotkb:y1842(locus name)|uniprotkb:YP_1810(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861750|imex:IM-13779-6668	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915.9(gene)|ensembl:ENST00000264933.9(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0014029""(neural crest formation)|go:""GO:0014032""(neural crest cell development)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0034605""(cellular response to heat)|go:""GO:0036324""(vascular endothelial growth factor receptor-2 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:1902527""(positive regulation of protein monoubiquitination)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR051426|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|dip:DIP-33217N|panther:PTHR46212(orthology-group)"	"mint:Q8D0P1|interpro:IPR011006(CheY-like)|interpro:IPR001789(Signal transduction response regulator, receiver region)|refseq:WP_002210873.1|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|interpro:IPR052048|refseq:YP_002346685.1|panther:PTHR43228(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606	rogid:wf5r24m07Zgglm31fBnlvBt1VVY632	intact-crc:01311558B0888496|rigid:mKdwCuoFGcejYvJQp8Q/uOD3bx0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PJ11	uniprotkb:Q15154	intact:EBI-2843240|uniprotkb:Q74SW1|uniprotkb:Q7CJT3|uniprotkb:A0A380PL96|uniprotkb:Q0WDP0	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|ensembl:ENSP00000327077.8|intact:EBI-16421643|intact:EBI-10961691	psi-mi:a0a2s9pj11_yerpe(display_long)|uniprotkb:proW(gene name)|psi-mi:proW(display_short)|uniprotkb:YPO2646(locus name)	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861797|imex:IM-13779-6673	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|refseq:WP_002212209.1|interpro:IPR035906|refseq:YP_002347598.1"	"efo:""Orphanet:146""|ensembl:ENSG00000078674.20(gene)|ensembl:ENST00000325083.13(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001764""(neuron migration)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0007098""(centrosome cycle)|go:""GO:0016020""(membrane)|go:""GO:0022027""(interkinetic nuclear migration)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034451""(centriolar satellite)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0034454""(microtubule anchoring at centrosome)|go:""GO:0035176""(social behavior)|go:""GO:0035735""(intraciliary transport involved in cilium assembly)|go:""GO:0035869""(ciliary transition zone)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060271""(cilium assembly)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0140706""(protein-containing complex localization to centriolar satellite)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|rcsb pdb:7Q46|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001302437.1|refseq:NP_006188.3|refseq:XP_016868972.1|refseq:XP_016868973.1|refseq:XP_016868983.1|refseq:XP_016868984.1|refseq:XP_016868985.1|dip:DIP-42189N|panther:PTHR14164(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:BBwCIsPUr1k5paTb1ggfStKFewc632	rogid:gV7sfdY5uU0egRgqblpnK4TeGB09606	intact-crc:BD4F0CB9A7695058|rigid:f/8JV3HkPn2oGX+SK2zqkHwUwV4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YFD8	uniprotkb:O94913	intact:EBI-2844797|uniprotkb:Q74TW8|uniprotkb:A0A0H2W658|uniprotkb:Q7CIM3|uniprotkb:A0A384L807	intact:EBI-2559809|ensembl:ENSP00000298281.4|uniprotkb:Q6P0X8|uniprotkb:A6H8W7|uniprotkb:O43671	psi-mi:a0a5p8yfd8_yerpe(display_long)|uniprotkb:trpE(gene name)|psi-mi:trpE(display_short)|uniprotkb:YPO2208(locus name)	psi-mi:pcf11_human(display_long)|uniprotkb:PCF11(gene name)|psi-mi:PCF11(display_short)|uniprotkb:KIAA0824(gene name synonym)|uniprotkb:Pre-mRNA cleavage complex II protein Pcf11(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861816|imex:IM-13779-6677	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR019999|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR005257(Anthranilate synthase component I, TrpE)|interpro:IPR015890(Chorismate binding, C-terminal)|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004049""(anthranilate synthase activity)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347179.1|panther:PTHR11236(orthology-group)"	"ensembl:ENSG00000165494.12(gene)|ensembl:ENST00000298281.8(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005849""(mRNA cleavage factor complex)|go:""GO:0006369""(termination of RNA polymerase II transcription)|go:""GO:0180010""(co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR021605|interpro:IPR045154|interpro:IPR047415|interpro:IPR048829|interpro:IPR048830|interpro:IPR048832|interpro:IPR054127|mint:O94913|rcsb pdb:6WJH|reactome:R-HSA-6807505|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_056969.2|dip:DIP-56825N|panther:PTHR15921(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4yY3KOTpkixAVvXxxbToZJUfRYM632	rogid:UcfmBNhPWm0PbZmQ2LkwK3WvKcU9606	intact-crc:C92E0C6857925239|rigid:GElfNBbOHobtMCi4P4+NENw9UkA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P29122	uniprotkb:Q7CL81	intact:EBI-2683528|uniprotkb:Q9UEJ8|uniprotkb:Q9UEJ9|uniprotkb:Q15100|uniprotkb:Q9Y4H1|uniprotkb:Q9UEJ1|uniprotkb:Q9Y4H0|uniprotkb:Q9UEJ2|uniprotkb:Q15099|uniprotkb:Q9UEJ7|uniprotkb:Q9Y4G9|uniprotkb:Q9UEG7|ensembl:ENSP00000482760.1	intact:EBI-2852239|uniprotkb:Q74PP8	psi-mi:pcsk6_human(display_long)|uniprotkb:PACE4(gene name synonym)|uniprotkb:Paired basic amino acid cleaving enzyme 4(gene name synonym)|uniprotkb:Subtilisin-like proprotein convertase 4(gene name synonym)|uniprotkb:Subtilisin/kexin-like protease PACE4(gene name synonym)|uniprotkb:PCSK6(gene name)|psi-mi:PCSK6(display_short)	psi-mi:q7cl81_yerpe(display_long)|uniprotkb:treB(gene name)|psi-mi:treB(display_short)|uniprotkb:YPO3697(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861783|imex:IM-13779-6672	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002561.1|refseq:NP_612192.1|refseq:NP_612195.1|refseq:NP_612196.1|refseq:NP_612197.1|refseq:NP_001278238.1|refseq:NP_612198.2|dip:DIP-29903N|ensembl:ENSG00000140479.18(gene)|ensembl:ENST00000611716.5(transcript)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007354""(zygotic determination of anterior/posterior axis, embryo)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0008201""(heparin binding)|go:""GO:0009100""(glycoprotein metabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016485""(protein processing)|go:""GO:0016486""(peptide hormone processing)|go:""GO:0030510""(regulation of BMP signaling pathway)|go:""GO:0032902""(nerve growth factor production)|go:""GO:0032940""(secretion by cell)|go:""GO:0034369""(plasma lipoprotein particle remodeling)|go:""GO:0048406""(nerve growth factor binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010909(PLAC)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032778|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|mint:P29122|reactome:R-HSA-1181150|reactome:R-HSA-167060|reactome:R-HSA-6809371|reactome:R-HSA-8963889|panther:PTHR42884(orthology-group)"	"interpro:IPR018113|interpro:IPR001996(Phosphotransferase system, EIIB)|interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR013013(Phosphotransferase system, EIIC component, type 1)|interpro:IPR011296(Phosphotransferase system, trehalose-specific IIBC component)|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0015574""(trehalose transmembrane transporter activity)|go:""GO:0015771""(trehalose transport)|go:""GO:0016301""(kinase activity)|go:""GO:0090589""(protein-phosphocysteine-trehalose phosphotransferase system transporter activity)|interpro:IPR036878|interpro:IPR050558|panther:PTHR30175(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xh7YAAyyc+G8pX8aiioRKS4PB/Y9606	rogid:MIkTe/Rb+6LtHGd0IvWHhqfr8ao632	intact-crc:6210238CF2790A7D|rigid:f5gm2RWtrJhTYf2Ymj1b5+IZzOA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15154	uniprotkb:A0A6M0NII6	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|ensembl:ENSP00000327077.8|intact:EBI-16421643|intact:EBI-10961691	intact:EBI-2841704	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	psi-mi:a0a6m0nii6_yerpe(display_long)|uniprotkb:y2471(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861790|imex:IM-13779-6676	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:146""|ensembl:ENSG00000078674.20(gene)|ensembl:ENST00000325083.13(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001764""(neuron migration)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0007098""(centrosome cycle)|go:""GO:0016020""(membrane)|go:""GO:0022027""(interkinetic nuclear migration)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034451""(centriolar satellite)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0034454""(microtubule anchoring at centrosome)|go:""GO:0035176""(social behavior)|go:""GO:0035735""(intraciliary transport involved in cilium assembly)|go:""GO:0035869""(ciliary transition zone)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060271""(cilium assembly)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0140706""(protein-containing complex localization to centriolar satellite)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|rcsb pdb:7Q46|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001302437.1|refseq:NP_006188.3|refseq:XP_016868972.1|refseq:XP_016868973.1|refseq:XP_016868983.1|refseq:XP_016868984.1|refseq:XP_016868985.1|dip:DIP-42189N|panther:PTHR14164(orthology-group)"	"uniprotkb:A0A6B3T0M9(uniprot-removed-ac)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR029016|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|refseq:WP_002228541.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:gV7sfdY5uU0egRgqblpnK4TeGB09606	rogid:d/mBSOpThH3MO4/Ze3GAgpPOK+o632	intact-crc:D73BF234B0BECAA9|rigid:HhqJ6rx24jThcF79Rm4KATpZ+c4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YBB3	uniprotkb:Q15154	intact:EBI-2861804|uniprotkb:Q74QZ0|uniprotkb:Q0WA67|uniprotkb:Q7CFY9|uniprotkb:A0A2U2GYG2|uniprotkb:A0A384KZW9	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|ensembl:ENSP00000327077.8|intact:EBI-16421643|intact:EBI-10961691	psi-mi:a0a5p8ybb3_yerpe(display_long)|uniprotkb:yhgN(gene name)|psi-mi:yhgN(display_short)|uniprotkb:YPO3950(locus name)	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861809|imex:IM-13779-6674	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002771(""Multiple antibiotic resistance (MarC)-related"")|go:""GO:0005886""(plasma membrane)|refseq:YP_002348821.1"	"efo:""Orphanet:146""|ensembl:ENSG00000078674.20(gene)|ensembl:ENST00000325083.13(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001764""(neuron migration)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0007098""(centrosome cycle)|go:""GO:0016020""(membrane)|go:""GO:0022027""(interkinetic nuclear migration)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034451""(centriolar satellite)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0034454""(microtubule anchoring at centrosome)|go:""GO:0035176""(social behavior)|go:""GO:0035735""(intraciliary transport involved in cilium assembly)|go:""GO:0035869""(ciliary transition zone)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060271""(cilium assembly)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0090316""(positive regulation of intracellular protein transport)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0140706""(protein-containing complex localization to centriolar satellite)|go:""GO:1905515""(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|rcsb pdb:7Q46|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001302437.1|refseq:NP_006188.3|refseq:XP_016868972.1|refseq:XP_016868973.1|refseq:XP_016868983.1|refseq:XP_016868984.1|refseq:XP_016868985.1|dip:DIP-42189N|panther:PTHR14164(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:FpTsR685Go8OapWrsNqoCYpu5c8632	rogid:gV7sfdY5uU0egRgqblpnK4TeGB09606	intact-crc:6C8FBF8D9C17DC1C|rigid:lcL2h/5fMwVtEY3+hfHgSfrFp9w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WUM4	uniprotkb:Q8ZCT2	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|ensembl:ENSP00000307387.3|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|intact:EBI-28983290|uniprotkb:C5MQH7|intact:EBI-10971645	intact:EBI-2861771|uniprotkb:Q0WD20	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	psi-mi:ndk_yerpe(display_long)|uniprotkb:ndk(gene name)|psi-mi:ndk(display_short)|uniprotkb:Nucleoside-2-P kinase(gene name synonym)|uniprotkb:YPO2883(locus name)|uniprotkb:y1349(locus name)|uniprotkb:YP_2749(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861776|imex:IM-13779-6675	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_037506.2|ensembl:ENSG00000170248.15(gene)|ensembl:ENST00000307296.8(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0000915""(actomyosin contractile ring assembly)|go:""GO:0001772""(immunological synapse)|go:""GO:0005768""(endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006915""(apoptotic process)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0031871""(proteinase activated receptor binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0042470""(melanosome)|go:""GO:0042641""(actomyosin)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045199""(maintenance of epithelial cell apical/basal polarity)|go:""GO:0046755""(viral budding)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0061952""(midbody abscission)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0070971""(endoplasmic reticulum exit site)|go:""GO:0090543""(Flemming body)|go:""GO:0090559""(regulation of membrane permeability)|go:""GO:0090611""(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0097734""(extracellular exosome biogenesis)|go:""GO:1903543""(positive regulation of exosomal secretion)|go:""GO:1903551""(regulation of extracellular exosome assembly)|go:""GO:1903553""(positive regulation of extracellular exosome assembly)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001155901.1|refseq:NP_001243121.1|dip:DIP-29327N|panther:PTHR23030(orthology-group)"	"interpro:IPR034907|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|go:""GO:0004550""(nucleoside diphosphate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006163""(purine nucleotide metabolic process)|go:""GO:0006183""(GTP biosynthetic process)|go:""GO:0006220""(pyrimidine nucleotide metabolic process)|go:""GO:0006228""(UTP biosynthetic process)|go:""GO:0006241""(CTP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR036850|refseq:WP_002209821.1|refseq:YP_002347818.1|panther:PTHR11349(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	rogid:f7gXgBxb5phwokUIDQjD0FRO/LI632	intact-crc:710DC228236B1B8B|rigid:0I64A1Gfe9m4K3qSXkBCjlIYCHc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15366	uniprotkb:A0A3N4BA87	intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|uniprotkb:B4DXP5|ensembl:ENSP00000408949.2	intact:EBI-2849383|uniprotkb:Q74PH8|uniprotkb:A0A0H2W8Y4|uniprotkb:Q7CL39|uniprotkb:A0A384L9C4	psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym)	psi-mi:a0a3n4ba87_yerpe(display_long)|uniprotkb:ISU59_19965(orf name)|uniprotkb:YPO3618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861844|imex:IM-13779-6679	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|ensembl:ENSG00000197111.16(gene)|ensembl:ENST00000439930.7(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0039694""(viral RNA genome replication)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045087""(innate immune response)|go:""GO:0050687""(negative regulation of defense response to virus)|go:""GO:0051607""(defense response to virus)|go:""GO:0070062""(extracellular exosome)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0106222""(lncRNA binding)|go:""GO:0140585""(promoter-enhancer loop anchoring activity)|go:""GO:0140588""(chromatin looping)|go:""GO:0160049""(negative regulation of cGAS/STING signaling pathway)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440|reactome:R-HSA-9692916|dip:DIP-58934N|panther:PTHR10288(orthology-group)"	"interpro:IPR004104(Oxidoreductase, C-terminal)|interpro:IPR000683(Oxidoreductase, N-terminal)|refseq:WP_002210025.1|go:""GO:0000166""(nucleotide binding)|go:""GO:0005829""(cytosol)|go:""GO:0017000""(antibiotic biosynthetic process)|go:""GO:0102497""(""scyllo-inositol dehydrogenase (NADP+) activity"")|interpro:IPR036291|refseq:YP_002348503.1|interpro:IPR051317|panther:PTHR43708(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606	rogid:oAKjFkWV9yeIL0iPB/h3xOcZxZw632	intact-crc:8029FC78E189D357|rigid:dt0EFriP+iUrQMfdPf68bFzLobI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W496	uniprotkb:O94913	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	intact:EBI-2559809|ensembl:ENSP00000298281.4|uniprotkb:Q6P0X8|uniprotkb:A6H8W7|uniprotkb:O43671	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	psi-mi:pcf11_human(display_long)|uniprotkb:PCF11(gene name)|psi-mi:PCF11(display_short)|uniprotkb:KIAA0824(gene name synonym)|uniprotkb:Pre-mRNA cleavage complex II protein Pcf11(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861823|imex:IM-13779-6682	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"ensembl:ENSG00000165494.12(gene)|ensembl:ENST00000298281.8(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005849""(mRNA cleavage factor complex)|go:""GO:0006369""(termination of RNA polymerase II transcription)|go:""GO:0180010""(co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR021605|interpro:IPR045154|interpro:IPR047415|interpro:IPR048829|interpro:IPR048830|interpro:IPR048832|interpro:IPR054127|mint:O94913|rcsb pdb:6WJH|reactome:R-HSA-6807505|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_056969.2|dip:DIP-56825N|panther:PTHR15921(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	rogid:UcfmBNhPWm0PbZmQ2LkwK3WvKcU9606	intact-crc:B7A94D76D8FCA226|rigid:CP+YNxYF1bcvSDLRUvlz3cTOO7Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1A4	uniprotkb:Q15366	intact:EBI-2850994	intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|uniprotkb:B4DXP5|ensembl:ENSP00000408949.2	psi-mi:q8d1a4_yerpe(display_long)|uniprotkb:y0798(locus name)|uniprotkb:fhuB(gene name)|psi-mi:fhuB(display_short)	psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861837|imex:IM-13779-6681	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000522(Bacterial transport system permease protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR037294"	"refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|ensembl:ENSG00000197111.16(gene)|ensembl:ENST00000439930.7(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0039694""(viral RNA genome replication)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045087""(innate immune response)|go:""GO:0050687""(negative regulation of defense response to virus)|go:""GO:0051607""(defense response to virus)|go:""GO:0070062""(extracellular exosome)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0106222""(lncRNA binding)|go:""GO:0140585""(promoter-enhancer loop anchoring activity)|go:""GO:0140588""(chromatin looping)|go:""GO:0160049""(negative regulation of cGAS/STING signaling pathway)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440|reactome:R-HSA-9692916|dip:DIP-58934N|panther:PTHR10288(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PGAfc4VH09eJJH0aF+uMggT6rQg632	rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606	intact-crc:2F2DD6E9580CD6CC|rigid:dywKjtOoBAK1iStAQvov0WbN/88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15365	uniprotkb:Q7CIC2	intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556.5	intact:EBI-2859615|uniprotkb:Q74U47	psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:znuc_yerpe(display_long)|uniprotkb:znuC(gene name)|psi-mi:znuC(display_short)|uniprotkb:YPO2060(locus name)|uniprotkb:y2250(locus name)|uniprotkb:YP_1903(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861851|imex:IM-13779-6680	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006187.2|ensembl:ENSG00000169564.7(gene)|ensembl:ENST00000303577.7(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0039694""(viral RNA genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098847""(sequence-specific single stranded DNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-38136N|ensembl:ENSP00000305556.5|panther:PTHR10288(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR050153|go:""GO:0005524""(ATP binding)|go:""GO:0010043""(response to zinc ion)|go:""GO:0015633""(ABC-type zinc transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|panther:PTHR42734(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606	rogid:bCxjpWeCg/VUwlIaWYH3ZI3h5tk632	intact-crc:D88FFC6FD6482017|rigid:o2Ch1gipmAQnSUfoyBf7NAoPjdU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14917	uniprotkb:A0A2U2H1V8	intact:EBI-947061|uniprotkb:Q5VVW9|uniprotkb:Q5VVX0|uniprotkb:A8K1R5|ensembl:ENSP00000367151.3	intact:EBI-2842206|uniprotkb:O68762|uniprotkb:Q74YK8|uniprotkb:A0A384KZR0|uniprotkb:A0A1U8QG56|uniprotkb:A0A0H2W1K6|uniprotkb:Q7ARD1	psi-mi:pcd17_human(display_long)|uniprotkb:PCDH17(gene name)|psi-mi:PCDH17(display_short)|uniprotkb:PCDH68(gene name synonym)|uniprotkb:PCH68(gene name synonym)|uniprotkb:Protocadherin-68(gene name synonym)	psi-mi:a0a2u2h1v8_yerpe(display_long)|uniprotkb:YPMT1.47c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861830|imex:IM-13779-6678	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035519.1|refseq:XP_005266414.1|ensembl:ENSG00000118946.12(gene)|ensembl:ENST00000377918.8(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0030534""(adult behavior)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0050805""(negative regulation of synaptic transmission)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0099560""(synaptic membrane adhesion)|go:""GO:1904071""(presynaptic active zone assembly)|go:""GO:2000807""(regulation of synaptic vesicle clustering)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR050174|rcsb pdb:6VFT|panther:PTHR24028(orthology-group)"	"refseq:NP_395390.1|refseq:YP_093935.1|refseq:WP_002222869.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SsQ6UvnneZMuyX5PGul6AUJOVp49606	rogid:HfbjH2+V5FcTdJjdFEwPlsVE9ek632	intact-crc:6AB23B355D811579|rigid:U8pi//nfVdMEyMzvrwWbw6zqXfE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86U86	uniprotkb:P17778	intact:EBI-637807|uniprotkb:Q9H2T3|uniprotkb:Q9H2T4|uniprotkb:Q9H2T5|uniprotkb:Q9H301|uniprotkb:Q9H314|uniprotkb:A1L381|uniprotkb:A1L382|uniprotkb:A4FUJ7|uniprotkb:Q1RMD1|uniprotkb:Q1RMD2|uniprotkb:Q96MS2|ensembl:ENSP00000296302.7	intact:EBI-2842665|uniprotkb:O68701	psi-mi:pb1_human(display_long)|uniprotkb:Polybromo-1D(gene name synonym)|uniprotkb:BRG1-associated factor 180(gene name synonym)|uniprotkb:PBRM1(gene name)|psi-mi:PBRM1(display_short)|uniprotkb:PB1(gene name synonym)|uniprotkb:BAF180(gene name synonym)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861870|imex:IM-13779-6686	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000163939.19(gene)|ensembl:ENST00000296302.11(transcript)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001487(Bromodomain)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR018359|interpro:IPR036427|interpro:IPR036910|interpro:IPR037382|interpro:IPR037968|interpro:IPR043151|mint:Q86U86|rcsb pdb:2KTB|rcsb pdb:3G0J|rcsb pdb:3HMF|rcsb pdb:3IU5|rcsb pdb:3IU6|rcsb pdb:3K2J|rcsb pdb:3LJW|rcsb pdb:3MB4|rcsb pdb:3TLP|rcsb pdb:4Q0N|rcsb pdb:4Q0O|rcsb pdb:4Y03|rcsb pdb:5E7D|rcsb pdb:5FH6|rcsb pdb:5FH7|rcsb pdb:5FH8|rcsb pdb:5HRV|rcsb pdb:5HRW|rcsb pdb:5HRX|rcsb pdb:5II1|rcsb pdb:5II2|rcsb pdb:5IID|rcsb pdb:6OXB|rcsb pdb:6ZN6|rcsb pdb:6ZNV|rcsb pdb:6ZS3|rcsb pdb:6ZS4|rcsb pdb:7VDV|rcsb pdb:7Y8R|rcsb pdb:8FTA|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_060783.3|refseq:NP_851385.1|refseq:XP_016862237.1|refseq:XP_016862238.1|refseq:XP_016862239.1|refseq:XP_016862246.1|refseq:XP_016862247.1|dip:DIP-33045N|efo:""Orphanet:404511""|panther:PTHR16062(orthology-group)|ensembl:ENSP00000296302.7|ensembl:ENST00000337303.8|ensembl:ENSP00000338302.4|ensembl:ENST00000356770.8|ensembl:ENSP00000349213.4|ensembl:ENST00000394830.7|ensembl:ENSP00000378307.3|ensembl:ENST00000409057.5|ensembl:ENSP00000386593.1|ensembl:ENST00000409114.7|ensembl:ENSP00000386643.3|ensembl:ENST00000409767.5|ensembl:ENSP00000386601.1|ensembl:ENST00000410007.5|ensembl:ENSP00000386529.1|ensembl:ENST00000412587.5|ensembl:ENSP00000404579.1"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/19	rogid:nJp9kwLE9qxj6DcyEO8dUok6k/Q9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:A296B298BD13C25C|rigid:DLoBEGN2tKpIELA/JBerTG4Eh5g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKK3	uniprotkb:Q8CZH4	intact:EBI-2623021|uniprotkb:Q5QNZ9|uniprotkb:O75903|uniprotkb:Q14682|uniprotkb:Q9H1M6|ensembl:ENSP00000371419.3	intact:EBI-2854937|uniprotkb:Q74QQ7	"psi-mi:parp4_human(display_long)|uniprotkb:ADPRTL1(gene name synonym)|uniprotkb:KIAA0177(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:193 kDa vault protein(gene name synonym)|uniprotkb:PARP-related/IalphaI-related H5/proline-rich(gene name synonym)|uniprotkb:""Vault poly(ADP-ribose) polymerase""(gene name synonym)|uniprotkb:PARP4(gene name)|psi-mi:PARP4(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 4(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 4(gene name synonym)"	psi-mi:q8czh4_yerpe(display_long)|uniprotkb:fimD7(gene name)|psi-mi:fimD7(display_short)|uniprotkb:YP_3405(locus name)|uniprotkb:y4062(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861887|imex:IM-13779-6685	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011533234.1|refseq:NP_006428.2|ensembl:ENSG00000102699.6(gene)|ensembl:ENST00000381989.4(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005876""(spindle microtubule)|go:""GO:0006281""(DNA repair)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016020""(membrane)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0036211""(protein modification process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140806""(NAD+-protein-aspartate ADP-ribosyltransferase activity)|go:""GO:0140822""(NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity)|go:""GO:0140844""(NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity)|go:""GO:0140867""(NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity)|go:""GO:1990404""(NAD+-protein mono-ADP-ribosyltransferase activity)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001357(BRCT)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004102(""Poly(ADP-ribose) polymerase, regulatory region"")|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR031273|interpro:IPR036420|interpro:IPR036465|interpro:IPR036616|mint:Q9UKK3|rcsb pdb:8SWY|rcsb pdb:8SWZ|rcsb pdb:8SX1|rcsb pdb:8SX2|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|panther:PTHR46530(orthology-group)"	"interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR018030|interpro:IPR025885|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR037224|refseq:WP_002228722.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:d1n+oei4ZSmqUnvJzMe6RLq2XOc9606	rogid:ShSR+MjoonLHZI8K/Cpx+R6F7DA632	intact-crc:48260990CF52C426|rigid:vrUqBvWKqUo69osRDaGd/eFaSYM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKK3	uniprotkb:Q8CZG2	intact:EBI-2623021|uniprotkb:Q5QNZ9|uniprotkb:O75903|uniprotkb:Q14682|uniprotkb:Q9H1M6|ensembl:ENSP00000371419.3	intact:EBI-2852858|uniprotkb:Q74PB8	"psi-mi:parp4_human(display_long)|uniprotkb:ADPRTL1(gene name synonym)|uniprotkb:KIAA0177(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:193 kDa vault protein(gene name synonym)|uniprotkb:PARP-related/IalphaI-related H5/proline-rich(gene name synonym)|uniprotkb:""Vault poly(ADP-ribose) polymerase""(gene name synonym)|uniprotkb:PARP4(gene name)|psi-mi:PARP4(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 4(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 4(gene name synonym)"	psi-mi:q8czg2_yerpe(display_long)|uniprotkb:cof4(gene name)|psi-mi:cof4(display_short)|uniprotkb:YP_4001(locus name)|uniprotkb:y4109(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861894|imex:IM-13779-6687	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011533234.1|refseq:NP_006428.2|ensembl:ENSG00000102699.6(gene)|ensembl:ENST00000381989.4(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005876""(spindle microtubule)|go:""GO:0006281""(DNA repair)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016020""(membrane)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0036211""(protein modification process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140806""(NAD+-protein-aspartate ADP-ribosyltransferase activity)|go:""GO:0140822""(NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity)|go:""GO:0140844""(NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity)|go:""GO:0140867""(NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity)|go:""GO:1990404""(NAD+-protein mono-ADP-ribosyltransferase activity)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001357(BRCT)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004102(""Poly(ADP-ribose) polymerase, regulatory region"")|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR031273|interpro:IPR036420|interpro:IPR036465|interpro:IPR036616|mint:Q9UKK3|rcsb pdb:8SWY|rcsb pdb:8SWZ|rcsb pdb:8SX1|rcsb pdb:8SX2|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|panther:PTHR46530(orthology-group)"	"interpro:IPR023214|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR000150(Cof protein)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0016791""(phosphatase activity)|interpro:IPR036412"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:d1n+oei4ZSmqUnvJzMe6RLq2XOc9606	rogid:lKd9FvoaPgE0/lQ/n5KXQSPPkdY632	intact-crc:97F90990CE9BB636|rigid:JozxN4ZwH3L5kN694ZOxQyFWTOU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49023	uniprotkb:Q8CLN8	intact:EBI-702209|uniprotkb:O14970|uniprotkb:O14971|uniprotkb:O60360|uniprotkb:B2RAI3|uniprotkb:Q5HYA4|uniprotkb:B7ZMB4|ensembl:ENSP00000228307.7	intact:EBI-2861880	psi-mi:paxi_human(display_long)|uniprotkb:PXN(gene name)|psi-mi:PXN(display_short)	psi-mi:q8cln8_yerpe(display_long)|uniprotkb:y0751(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861877|imex:IM-13779-6684	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001074324.1|refseq:NP_002850.2|refseq:NP_079433.3|refseq:NP_001230685.1|ensembl:ENSG00000089159.17(gene)|ensembl:ENST00000228307.11(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005829""(cytosol)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007172""(signal complex assembly)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0016477""(cell migration)|go:""GO:0017166""(vinculin binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0038191""(neuropilin binding)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0060396""(growth hormone receptor signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001904(Paxillin)|interpro:IPR047072|interpro:IPR047075|mint:P49023|rcsb pdb:1OW6|rcsb pdb:1OW7|rcsb pdb:1OW8|rcsb pdb:2K2R|rcsb pdb:2O9V|rcsb pdb:2VZD|rcsb pdb:2VZG|rcsb pdb:2VZI|rcsb pdb:3GM1|rcsb pdb:3PY7|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3U3F|rcsb pdb:4EDN|rcsb pdb:4R32|rcsb pdb:4XGZ|rcsb pdb:4XH2|rcsb pdb:5UWH|rcsb pdb:6IUI|rcsb pdb:6PW8|rcsb pdb:6U4M|rcsb pdb:6U4N|rcsb pdb:7QB0|reactome:R-HSA-180292|reactome:R-HSA-4420097|reactome:R-HSA-445355|reactome:R-HSA-446343|reactome:R-HSA-446388|reactome:R-HSA-8849471|refseq:XP_016875232.1|dip:DIP-33851N|panther:PTHR24216(orthology-group)"	interpro:IPR036890	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:H8osAQRrVydLfDL97uSSA6Mf6ME9606	rogid:wDywQUFSDw92X69T1UHVEq1kLec632	intact-crc:A023FCD41ED06757|rigid:W5yRsfJbp7jAsaOIHlrlMxGLN68	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VA48	uniprotkb:Q15365	intact:EBI-2861858	intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556.5	psi-mi:a0a6b3va48_yerpe(display_long)|uniprotkb:cytR(gene name)|psi-mi:cytR(display_short)|uniprotkb:cytR2(gene name synonym)|uniprotkb:cytR_3(gene name synonym)|uniprotkb:NCTC5923_02401(orf name)|uniprotkb:YP_3443(locus name)|uniprotkb:y3436(locus name)	psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861863|imex:IM-13779-6683	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T8T2(uniprot-removed-ac)|interpro:IPR000843(Bacterial regulatory protein, LacI)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR028082|go:""GO:0003677""(DNA binding)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR046335|refseq:WP_002211406.1"	"refseq:NP_006187.2|ensembl:ENSG00000169564.7(gene)|ensembl:ENST00000303577.7(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0039694""(viral RNA genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098847""(sequence-specific single stranded DNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-38136N|ensembl:ENSP00000305556.5|panther:PTHR10288(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:soNVkgWj2yKAkG4mmhZSIknJEgE632	rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606	intact-crc:A1A933C757BE4580|rigid:/DP5R7PvqniyakgY/zIjphEl+oc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKK3	uniprotkb:Q8ZFB2	intact:EBI-2623021|uniprotkb:Q5QNZ9|uniprotkb:O75903|uniprotkb:Q14682|uniprotkb:Q9H1M6|ensembl:ENSP00000371419.3	intact:EBI-2842002|uniprotkb:Q0WFY8|uniprotkb:Q8CWH3|uniprotkb:Q74UV7	"psi-mi:parp4_human(display_long)|uniprotkb:ADPRTL1(gene name synonym)|uniprotkb:KIAA0177(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:193 kDa vault protein(gene name synonym)|uniprotkb:PARP-related/IalphaI-related H5/proline-rich(gene name synonym)|uniprotkb:""Vault poly(ADP-ribose) polymerase""(gene name synonym)|uniprotkb:PARP4(gene name)|psi-mi:PARP4(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 4(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 4(gene name synonym)"	psi-mi:flgh2_yerpe(display_long)|uniprotkb:flgH2(gene name)|psi-mi:flgH2(display_short)|uniprotkb:Basal body L-ring protein 2(gene name synonym)|uniprotkb:YPO1805(locus name)|uniprotkb:y2504(locus name)|uniprotkb:YP_1588(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861915|imex:IM-13779-6691	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011533234.1|refseq:NP_006428.2|ensembl:ENSG00000102699.6(gene)|ensembl:ENST00000381989.4(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005876""(spindle microtubule)|go:""GO:0006281""(DNA repair)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016020""(membrane)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0036211""(protein modification process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140806""(NAD+-protein-aspartate ADP-ribosyltransferase activity)|go:""GO:0140822""(NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity)|go:""GO:0140844""(NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity)|go:""GO:0140867""(NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity)|go:""GO:1990404""(NAD+-protein mono-ADP-ribosyltransferase activity)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001357(BRCT)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004102(""Poly(ADP-ribose) polymerase, regulatory region"")|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR031273|interpro:IPR036420|interpro:IPR036465|interpro:IPR036616|mint:Q9UKK3|rcsb pdb:8SWY|rcsb pdb:8SWZ|rcsb pdb:8SX1|rcsb pdb:8SX2|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|panther:PTHR46530(orthology-group)"	"interpro:IPR000527(Flagellar L-ring protein)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009427""(bacterial-type flagellum basal body, distal rod, L ring)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:WP_002211116.1|refseq:YP_002346800.1|panther:PTHR34933(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:d1n+oei4ZSmqUnvJzMe6RLq2XOc9606	rogid:K+hG2Y1XkdBPEZly69izKbuTRvo632	intact-crc:805EB479CE9A9F68|rigid:/pQ34OWtA92yz80tzJDDCbE/7Vo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TEW8	uniprotkb:Q8ZBM5	intact:EBI-2861929|uniprotkb:Q8IUC9|uniprotkb:Q96NX6|uniprotkb:Q96NX7|uniprotkb:Q96DK9|uniprotkb:Q8IUC7|uniprotkb:Q96N09|uniprotkb:Q96Q29|uniprotkb:E9PE87|ensembl:ENSP00000385848.2	intact:EBI-2843506|uniprotkb:Q0WBR3	psi-mi:par3l_human(display_long)|uniprotkb:PARD3B(gene name)|psi-mi:PARD3B(display_short)|uniprotkb:ALS2CR19(gene name synonym)|uniprotkb:PAR3B(gene name synonym)|uniprotkb:PAR3L(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein(gene name synonym)|uniprotkb:PAR3-beta(gene name synonym)|uniprotkb:Partitioning defective 3-like protein(gene name synonym)	psi-mi:dgtp_yerpe(display_long)|uniprotkb:dgt(gene name)|psi-mi:dgt(display_short)|uniprotkb:YPO3383(locus name)|uniprotkb:y0806(locus name)|uniprotkb:YP_0302(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861941|imex:IM-13779-6690	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_476518.4|refseq:NP_689739.4|refseq:NP_995585.2|refseq:NP_001289698.1|dip:DIP-42276N|ensembl:ENSG00000116117.20(gene)|ensembl:ENST00000406610.7(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0008104""(protein localization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030054""(cell junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0051301""(cell division)|go:""GO:0051660""(establishment of centrosome localization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|interpro:IPR052213|mint:Q8TEW8|panther:PTHR16484(orthology-group)"	"interpro:IPR006261(Deoxyguanosinetriphosphate triphosphohydrolase)|interpro:IPR023293|interpro:IPR020779|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR026875|go:""GO:0000287""(magnesium ion binding)|go:""GO:0006203""(dGTP catabolic process)|go:""GO:0008832""(dGTPase activity)|refseq:WP_002209369.1|refseq:YP_002348275.1|interpro:IPR050135|panther:PTHR11373(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:68iR8w+iTdxuwBYs+HGumldBFQs9606	rogid:W9U0OTGxW9YIGgAtcpzcULXNA2M632	intact-crc:C6C49B63169C7634|rigid:k5Q6yUjOLPRmaJseYCL5pG2Ur3I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09874	uniprotkb:A0A2S9PFE9	intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759.5	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	"psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:""NAD(+) ADP-ribosyltransferase 1""(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)"	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861922|imex:IM-13779-6689	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001609.2|ensembl:ENSG00000143799.14(gene)|ensembl:ENST00000366794.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010613""(positive regulation of cardiac muscle hypertrophy)|go:""GO:0016020""(membrane)|go:""GO:0016051""(carbohydrate biosynthetic process)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0016604""(nuclear body)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0023019""(signal transduction involved in regulation of gene expression)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030592""(DNA ADP-ribosylation)|go:""GO:0031491""(nucleosome binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032042""(mitochondrial DNA metabolic process)|go:""GO:0032786""(positive regulation of DNA-templated transcription, elongation)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0033148""(positive regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036211""(protein modification process)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043504""(mitochondrial DNA repair)|go:""GO:0043596""(nuclear replication fork)|go:""GO:0045087""(innate immune response)|go:""GO:0045188""(regulation of circadian sleep/wake cycle, non-REM sleep)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046697""(decidualization)|go:""GO:0050790""(regulation of catalytic activity)|go:""GO:0051287""(NAD binding)|go:""GO:0051901""(positive regulation of mitochondrial depolarization)|go:""GO:0060391""(positive regulation of SMAD protein signal transduction)|go:""GO:0060545""(positive regulation of necroptotic process)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070212""(protein poly-ADP-ribosylation)|go:""GO:0070213""(protein auto-ADP-ribosylation)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0071168""(protein localization to chromatin)|go:""GO:0071294""(cellular response to zinc ion)|go:""GO:0071932""(replication fork reversal)|go:""GO:0090734""(site of DNA damage)|go:""GO:0140294""(NAD DNA ADP-ribosyltransferase activity)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:0140805""(NAD+-protein-serine ADP-ribosyltransferase activity)|go:""GO:0140806""(NAD+-protein-aspartate ADP-ribosyltransferase activity)|go:""GO:0140807""(NAD+-protein-glutamate ADP-ribosyltransferase activity)|go:""GO:0140808""(NAD+-protein-tyrosine ADP-ribosyltransferase activity)|go:""GO:0140815""(NAD+-protein-histidine ADP-ribosyltransferase activity)|go:""GO:0140816""(NAD+-histone H2BS6 serine ADP-ribosyltransferase activity)|go:""GO:0140817""(NAD+-histone H3S10 serine ADP-ribosyltransferase activity)|go:""GO:0140822""(NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity)|go:""GO:0140844""(NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity)|go:""GO:0140867""(NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity)|go:""GO:0160049""(negative regulation of cGAS/STING signaling pathway)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903376""(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:""GO:1903518""(positive regulation of single strand break repair)|go:""GO:1904044""(response to aldosterone)|go:""GO:1904178""(negative regulation of adipose tissue development)|go:""GO:1904357""(negative regulation of telomere maintenance via telomere lengthening)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1904762""(positive regulation of myofibroblast differentiation)|go:""GO:1905051""(regulation of base-excision repair)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990404""(NAD+-protein mono-ADP-ribosyltransferase activity)|go:""GO:1990966""(ATP generation from poly-ADP-D-ribose)|go:""GO:2001170""(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102(""Poly(ADP-ribose) polymerase, regulatory region"")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|interpro:IPR049296|interpro:IPR050800|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|rcsb pdb:2L30|rcsb pdb:2L31|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:4ZZZ|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:6VKK|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:7CMW|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|rcsb pdb:7ONR|rcsb pdb:7ONS|rcsb pdb:7ONT|rcsb pdb:7S68|rcsb pdb:7S6H|rcsb pdb:7S6M|rcsb pdb:7S81|rcsb pdb:7SCY|rcsb pdb:7SCZ|rcsb pdb:8FYY|rcsb pdb:8FYZ|rcsb pdb:8FZ1|rcsb pdb:8G0H|rcsb pdb:8HE7|rcsb pdb:8HLR|rcsb pdb:8JNZ|rcsb pdb:8U4W|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|dip:DIP-38N|panther:PTHR10459(orthology-group)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	intact-crc:E68DB7FB0DEDA1BD|rigid:CqT/oMxglSxBhrm7479H7xoEUkY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YFD8	uniprotkb:Q9UKK3	intact:EBI-2844797|uniprotkb:Q74TW8|uniprotkb:A0A0H2W658|uniprotkb:Q7CIM3|uniprotkb:A0A384L807	intact:EBI-2623021|uniprotkb:Q5QNZ9|uniprotkb:O75903|uniprotkb:Q14682|uniprotkb:Q9H1M6|ensembl:ENSP00000371419.3	psi-mi:a0a5p8yfd8_yerpe(display_long)|uniprotkb:trpE(gene name)|psi-mi:trpE(display_short)|uniprotkb:YPO2208(locus name)	"psi-mi:parp4_human(display_long)|uniprotkb:ADPRTL1(gene name synonym)|uniprotkb:KIAA0177(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:193 kDa vault protein(gene name synonym)|uniprotkb:PARP-related/IalphaI-related H5/proline-rich(gene name synonym)|uniprotkb:""Vault poly(ADP-ribose) polymerase""(gene name synonym)|uniprotkb:PARP4(gene name)|psi-mi:PARP4(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 4(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 4(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861901|imex:IM-13779-6692	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR019999|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR005257(Anthranilate synthase component I, TrpE)|interpro:IPR015890(Chorismate binding, C-terminal)|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004049""(anthranilate synthase activity)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347179.1|panther:PTHR11236(orthology-group)"	"refseq:XP_011533234.1|refseq:NP_006428.2|ensembl:ENSG00000102699.6(gene)|ensembl:ENST00000381989.4(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005876""(spindle microtubule)|go:""GO:0006281""(DNA repair)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016020""(membrane)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0036211""(protein modification process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140806""(NAD+-protein-aspartate ADP-ribosyltransferase activity)|go:""GO:0140822""(NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity)|go:""GO:0140844""(NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity)|go:""GO:0140867""(NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity)|go:""GO:1990404""(NAD+-protein mono-ADP-ribosyltransferase activity)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001357(BRCT)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004102(""Poly(ADP-ribose) polymerase, regulatory region"")|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR031273|interpro:IPR036420|interpro:IPR036465|interpro:IPR036616|mint:Q9UKK3|rcsb pdb:8SWY|rcsb pdb:8SWZ|rcsb pdb:8SX1|rcsb pdb:8SX2|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|panther:PTHR46530(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4yY3KOTpkixAVvXxxbToZJUfRYM632	rogid:d1n+oei4ZSmqUnvJzMe6RLq2XOc9606	intact-crc:53B50D7C58BE89B1|rigid:ydLqdR28jB8n0iWVQmxu2e6gaew	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YEP4	uniprotkb:Q9UKK3	intact:EBI-2842292|uniprotkb:Q74UV4|uniprotkb:Q7CHX9|uniprotkb:A0A2S9PKJ9|uniprotkb:Q0WFZ1	intact:EBI-2623021|uniprotkb:Q5QNZ9|uniprotkb:O75903|uniprotkb:Q14682|uniprotkb:Q9H1M6|ensembl:ENSP00000371419.3	psi-mi:a0a5p8yep4_yerpe(display_long)|uniprotkb:Fla FV(gene name)|psi-mi:Fla FV(display_short)|uniprotkb:flaK(gene name synonym)|uniprotkb:flgE(gene name synonym)|uniprotkb:YPO1802(locus name)	"psi-mi:parp4_human(display_long)|uniprotkb:ADPRTL1(gene name synonym)|uniprotkb:KIAA0177(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:193 kDa vault protein(gene name synonym)|uniprotkb:PARP-related/IalphaI-related H5/proline-rich(gene name synonym)|uniprotkb:""Vault poly(ADP-ribose) polymerase""(gene name synonym)|uniprotkb:PARP4(gene name)|psi-mi:PARP4(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 4(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 4(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861908|imex:IM-13779-6688	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR019776|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:WP_002211113.1|interpro:IPR037058|interpro:IPR037925|interpro:IPR053967|refseq:YP_002346797.1"	"refseq:XP_011533234.1|refseq:NP_006428.2|ensembl:ENSG00000102699.6(gene)|ensembl:ENST00000381989.4(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003950""(NAD+ poly-ADP-ribosyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005876""(spindle microtubule)|go:""GO:0006281""(DNA repair)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016020""(membrane)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0036211""(protein modification process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140806""(NAD+-protein-aspartate ADP-ribosyltransferase activity)|go:""GO:0140822""(NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity)|go:""GO:0140844""(NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity)|go:""GO:0140867""(NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity)|go:""GO:1990404""(NAD+-protein mono-ADP-ribosyltransferase activity)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001357(BRCT)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004102(""Poly(ADP-ribose) polymerase, regulatory region"")|interpro:IPR012317(""Poly(ADP-ribose) polymerase, catalytic region"")|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR031273|interpro:IPR036420|interpro:IPR036465|interpro:IPR036616|mint:Q9UKK3|rcsb pdb:8SWY|rcsb pdb:8SWZ|rcsb pdb:8SX1|rcsb pdb:8SX2|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|panther:PTHR46530(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BoYVEh/qtD+LMyJcZpSfUZt9yTk632	rogid:d1n+oei4ZSmqUnvJzMe6RLq2XOc9606	intact-crc:5B14EBD3CD54F56A|rigid:YYid4D+K1OqWBNSe3ssTzLmq9UM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YLY5	uniprotkb:Q8NC51	intact:EBI-2840998|uniprotkb:A0A384LAN6|uniprotkb:Q74Y20|uniprotkb:Q7CFW0|uniprotkb:Q0WKE1	intact:EBI-523558|ensembl:ENSP00000360034.2|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|uniprotkb:Q5VU20|uniprotkb:Q5VU22	psi-mi:a0a5p8yly5_yerpe(display_long)|uniprotkb:nirB(gene name)|psi-mi:nirB(display_short)|uniprotkb:YPO0161(locus name)	psi-mi:serb1_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 1 RNA-binding protein(gene name synonym)|uniprotkb:CGI-55(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861962|imex:IM-13779-6694	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002345247.1|interpro:IPR007419(BFD-like [2Fe-2S]-binding region)|interpro:IPR005117(Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like)|interpro:IPR012744(""Nitrite reductase [NAD(P)H] large subunit, NirB"")|interpro:IPR017121(""Nitrite reductase [NAD(P)H], large subunit"")|interpro:IPR006067(Nitrite and sulphite reductase 4Fe-4S region)|interpro:IPR006066(Nitrite and sulphite reductase iron-sulphur/siroheme-binding site)|interpro:IPR023753|interpro:IPR041575|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|go:""GO:0020037""(heme binding)|go:""GO:0042128""(nitrate assimilation)|go:""GO:0046872""(metal ion binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0050661""(NADP binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0098809""(nitrite reductase activity)|refseq:WP_002208886.1|interpro:IPR036136|interpro:IPR036188|interpro:IPR041854|interpro:IPR052034|interpro:IPR045854|panther:PTHR43809(orthology-group)"	"ensembl:ENSG00000142864.15(gene)|ensembl:ENST00000370995.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030371""(translation repressor activity)|go:""GO:0030578""(PML body organization)|go:""GO:0032183""(SUMO binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061770""(translation elongation factor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0141014""(ribosome hibernation)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:8K2C|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8Y0W|rcsb pdb:8Y0X|refseq:NP_001018078.1|refseq:NP_001018077.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N|panther:PTHR12299(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:6u3Rf93p+0SPTDFZ4PpmLjcphzY632	rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606	intact-crc:860E3102E7030F8B|rigid:C1I3MxJStglnxn90INUbE1pebtw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZR4	uniprotkb:Q13093	intact:EBI-2855892|uniprotkb:Q74RV7	intact:EBI-2828127|uniprotkb:Q8IVA2|uniprotkb:Q5VTT1|uniprotkb:Q15692|uniprotkb:A5HTT5|ensembl:ENSP00000274793.7|ensembl:ENSP00000445666.1	psi-mi:q8czr4_yerpe(display_long)|uniprotkb:fadH(gene name)|psi-mi:fadH(display_short)|uniprotkb:YP_2909(locus name)|uniprotkb:y3589(locus name)	psi-mi:pafa_human(display_long)|uniprotkb:PLA2G7(gene name)|psi-mi:PLA2G7(display_short)|uniprotkb:PAFAH(gene name synonym)|uniprotkb:1-alkyl-2-acetylglycerophosphocholine esterase(gene name synonym)|uniprotkb:2-acetyl-1-alkylglycerophosphocholine esterase(gene name synonym)|uniprotkb:Group-VIIA phospholipase A2(gene name synonym)|uniprotkb:LDL-associated phospholipase A2(gene name synonym)|uniprotkb:PAF 2-acylhydrolase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861976|imex:IM-13779-6697	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051793|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR001155(""NADH:flavin oxidoreductase/NADH oxidase, N-terminal"")|interpro:IPR023753|go:""GO:0009056""(catabolic process)|go:""GO:0010181""(FMN binding)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR036188"	"refseq:NP_001161829.1|refseq:NP_005075.3|refseq:XP_005249465.1|ensembl:ENSG00000146070.17(gene)|ensembl:ENST00000274793.12(transcript)|ensembl:ENST00000537365.1(transcript)|go:""GO:0003847""(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0016486""(peptide hormone processing)|go:""GO:0016788""(hydrolase activity, acting on ester bonds)|go:""GO:0034362""(low-density lipoprotein particle)|go:""GO:0034364""(high-density lipoprotein particle)|go:""GO:0034374""(low-density lipoprotein particle remodeling)|go:""GO:0034440""(lipid oxidation)|go:""GO:0034441""(plasma lipoprotein particle oxidation)|go:""GO:0034638""(phosphatidylcholine catabolic process)|go:""GO:0046469""(platelet activating factor metabolic process)|go:""GO:0047499""(calcium-independent phospholipase A2 activity)|go:""GO:0050729""(positive regulation of inflammatory response)|rcsb pdb:3F96|go:""GO:0062234""(platelet activating factor catabolic process)|go:""GO:0090026""(positive regulation of monocyte chemotaxis)|interpro:IPR016715(PAF acetylhydrolase)|interpro:IPR029058|rcsb pdb:3D59|rcsb pdb:3D5E|rcsb pdb:3F97|rcsb pdb:3F98|rcsb pdb:3F9C|rcsb pdb:5I8P|rcsb pdb:5I9I|rcsb pdb:5JAD|rcsb pdb:5JAH|rcsb pdb:5JAL|rcsb pdb:5JAN|rcsb pdb:5JAO|rcsb pdb:5JAP|rcsb pdb:5JAR|rcsb pdb:5JAS|rcsb pdb:5JAT|rcsb pdb:5JAU|rcsb pdb:5LP1|rcsb pdb:5LYY|rcsb pdb:5LZ2|rcsb pdb:5LZ4|rcsb pdb:5LZ5|rcsb pdb:5LZ7|rcsb pdb:5LZ8|rcsb pdb:5LZ9|rcsb pdb:5YE7|rcsb pdb:5YE8|rcsb pdb:5YE9|rcsb pdb:5YEA|rcsb pdb:6M06|rcsb pdb:6M07|rcsb pdb:6M08|reactome:R-HSA-422085|panther:PTHR10272(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kqq7pmkhywQcq//4gaGgZV8Wz3o632	rogid:sIQBLnsepccGTe/560SUqLJ7EGw9606	intact-crc:F02BBB487725E0E9|rigid:gXshpzpTXAdgDdje+xgqzwonkvw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W7E2	uniprotkb:Q504Q3	intact:EBI-2848155|uniprotkb:A0A2U2H0T1|uniprotkb:Q74QL8|uniprotkb:Q0WI49|uniprotkb:Q7CGN6|uniprotkb:A0A384KKB9	intact:EBI-1058976|uniprotkb:Q76E12|uniprotkb:O75189|uniprotkb:Q8IVE1|intact:EBI-2513034|ensembl:ENSP00000401721.2|ensembl:ENSP00000449861.1|ensembl:ENSP00000481859.1	psi-mi:a0a0h2w7e2_yerpe(display_long)|uniprotkb:iutA(gene name)|psi-mi:iutA(display_short)|uniprotkb:YPO0994(locus name)	"psi-mi:pan2_human(display_long)|uniprotkb:PAN2(gene name)|psi-mi:PAN2(display_short)|uniprotkb:KIAA0710(gene name synonym)|uniprotkb:USP52(gene name synonym)|uniprotkb:Inactive ubiquitin carboxyl-terminal hydrolase 52(gene name synonym)|uniprotkb:""PAB1P-dependent poly(A)-specific ribonuclease""(gene name synonym)|uniprotkb:""Poly(A)-nuclease deadenylation complex subunit 2""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861955|imex:IM-13779-6696	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|refseq:WP_002211646.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002346039.1"	"refseq:NP_001120932.1|refseq:NP_001159751.1|refseq:NP_055686.3|ensembl:ENSG00000135473.16(gene)|ensembl:ENST00000425394.7(transcript)|ensembl:ENST00000548043.5(transcript)|ensembl:ENST00000610546.4(transcript)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000289""(""nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0000932""(P-body)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0004535""(""poly(A)-specific ribonuclease activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0010606""(positive regulation of cytoplasmic mRNA processing body assembly)|go:""GO:0031251""(PAN complex)|go:""GO:0046872""(metal ion binding)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR028881|interpro:IPR028889|interpro:IPR030843|interpro:IPR036322|interpro:IPR036397|interpro:IPR038765|interpro:IPR048841|interpro:IPR050785|reactome:R-HSA-429947|dip:DIP-50708N|panther:PTHR15728(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/14	rogid:h+zziPxtFmhqRng+3zCsRqmsI/M632	rogid:2q3q4qXEhEU25TR01JaiCy1T8HE9606	intact-crc:618CB45230B1B16F|rigid:74k8SKJ0ybSRdT5rF9qY7FEyQsw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CWG4	uniprotkb:P51003	intact:EBI-2856530|uniprotkb:Q74QZ9	intact:EBI-359376|uniprotkb:Q86SX4|uniprotkb:Q86TV0|uniprotkb:Q8IYF5|uniprotkb:Q9BVU2|ensembl:ENSP00000216277.8	psi-mi:q8cwg4_yerpe(display_long)|uniprotkb:glpD(gene name)|psi-mi:glpD(display_short)|uniprotkb:YP_3299(locus name)|uniprotkb:y3891(locus name)	psi-mi:papoa_human(display_long)|uniprotkb:PAPOLA(gene name)|psi-mi:PAPOLA(display_short)|uniprotkb:PAP(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861948|imex:IM-13779-6693	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR031656|go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0006072""(glycerol-3-phosphate metabolic process)|go:""GO:0009331""(""glycerol-3-phosphate dehydrogenase (FAD) complex"")|interpro:IPR038299|interpro:IPR036188"	"refseq:NP_116021.2|refseq:NP_001238935.1|refseq:NP_001238936.1|refseq:NP_001280556.1|refseq:NP_001280557.1|refseq:NP_001280561.1|ensembl:ENSG00000090060.19(gene)|ensembl:ENST00000216277.13(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0030145""(manganese ion binding)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0180010""(co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway)|go:""GO:0180011""(cytosolic mRNA polyadenylation)|go:""GO:1990817""(""poly(A) RNA polymerase activity"")|interpro:IPR007010(""Poly(A) polymerase, RNA-binding region"")|interpro:IPR007012(""Poly(A) polymerase, central region"")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR014492(""Poly(A) polymerase"")|interpro:IPR043519|interpro:IPR048840|mint:P51003|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-27610N|dip:DIP-40865N|panther:PTHR10682(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:R9I22ZXVmXiKYYz/+NgwNjlHCb0632	rogid:rRMBZRE1yFjnO+pnz5g4k+u7hwo9606	intact-crc:65DD7F2B18995B9F|rigid:KqvdOTWLRNvOYlEBblriAr3/AUI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H074	uniprotkb:Q8CZK5	intact:EBI-81519|uniprotkb:O60455|uniprotkb:Q96B61|uniprotkb:Q9BS63|ensembl:ENSP00000302768.3|intact:EBI-28983264|intact:EBI-11149865|uniprotkb:A6NKV8	intact:EBI-2845872|uniprotkb:Q74QX9	psi-mi:paip1_human(display_long)|uniprotkb:PAIP1(gene name)|psi-mi:PAIP1(display_short)	psi-mi:q8czk5_yerpe(display_long)|uniprotkb:fba(gene name)|psi-mi:fba(display_short)|uniprotkb:YP_3323(locus name)|uniprotkb:y3869(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861969|imex:IM-13779-6695	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006442.2|refseq:NP_877590.1|refseq:NP_899152.1|ensembl:ENSG00000172239.14(gene)|ensembl:ENST00000306846.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0008494""(translation activator activity)|go:""GO:0019081""(viral translation)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0106002""(mCRD-mediated mRNA stability complex)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR051367|mint:Q9H074|rcsb pdb:1JH4|rcsb pdb:3NTW|rcsb pdb:3RK6|rcsb pdb:6YXJ|reactome:R-HSA-429947|reactome:R-HSA-9820841|reactome:R-HSA-9820865|panther:PTHR23254(orthology-group)|refseq:XP_005248287.1|refseq:XP_016864445.1"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000771(Ketose-bisphosphate aldolase, class-II)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016832""(aldehyde-lyase activity)|interpro:IPR050246"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/06	rogid:KPInpN26l8XAnUKFawoVUhwKM9w9606	rogid:F4QkMnJWZdUUOo6ENRO8BbcEL+I632	intact-crc:19FD8655A8EAAEB1|rigid:hpldDI9BD/Diyczn+8oWk2K0s1k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZC49	uniprotkb:P11940	intact:EBI-2852010|uniprotkb:Q0WCB0	intact:EBI-81531|intact:EBI-28983164|uniprotkb:Q15097|uniprotkb:Q93004|ensembl:ENSP00000313007.5|ensembl:ENSP00000428749.2|ensembl:ENSP00000428840.2|ensembl:ENSP00000429119.2|ensembl:ENSP00000429790.2|ensembl:ENSP00000429892.2|ensembl:ENSP00000430012.2	psi-mi:thii_yerpe(display_long)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:YPO3173(locus name)|uniprotkb:y1012(locus name)|uniprotkb:YP_0758(locus name)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861997|imex:IM-13779-6701	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026340|interpro:IPR001763(Rhodanese-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|refseq:WP_002208658.1|go:""GO:0000049""(tRNA binding)|go:""GO:0002937""(tRNA 4-thiouridine biosynthesis)|go:""GO:0004810""(CCA tRNA nucleotidyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0052837""(thiazole biosynthetic process)|go:""GO:0140741""(tRNA-uracil-4 sulfurtransferase activity)|interpro:IPR036873|interpro:IPR054173|refseq:YP_002348078.1|interpro:IPR049961|interpro:IPR049962|interpro:IPR050102|panther:PTHR43209(orthology-group)"	"refseq:NP_002559.2|ensembl:ENSG00000070756.17(gene)|ensembl:ENST00000318607.10(transcript)|ensembl:ENST00000520142.2(transcript)|ensembl:ENST00000520804.2(transcript)|ensembl:ENST00000521865.6(transcript)|ensembl:ENST00000522658.6(transcript)|ensembl:ENST00000522720.2(transcript)|ensembl:ENST00000523555.6(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008494""(translation activator activity)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031252""(cell leading edge)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0106002""(mCRD-mediated mRNA stability complex)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000623""(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034364|interpro:IPR035979|interpro:IPR036053|interpro:IPR045305|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|rcsb pdb:7BN3|rcsb pdb:8SMO|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9820841|reactome:R-HSA-9820865|panther:PTHR24012(orthology-group)|refseq:XP_005250918.1|dip:DIP-31613N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:JVdYYtaSxHT0xyr6zYDRPl2jCF4632	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:8F72B195D01A9E30|rigid:6ZHlEWqrC6wLIldWFwG6ePSALN4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11940	uniprotkb:A0A3N4B631	intact:EBI-81531|intact:EBI-28983164|uniprotkb:Q15097|uniprotkb:Q93004|ensembl:ENSP00000313007.5|ensembl:ENSP00000428749.2|ensembl:ENSP00000428840.2|ensembl:ENSP00000429119.2|ensembl:ENSP00000429790.2|ensembl:ENSP00000429892.2|ensembl:ENSP00000430012.2	intact:EBI-2859968|uniprotkb:Q74VK7|uniprotkb:Q0WHB8|uniprotkb:Q7CHE6	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:a0a3n4b631_yerpe(display_long)|uniprotkb:YPO1294(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862015|imex:IM-13779-6700	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002559.2|ensembl:ENSG00000070756.17(gene)|ensembl:ENST00000318607.10(transcript)|ensembl:ENST00000520142.2(transcript)|ensembl:ENST00000520804.2(transcript)|ensembl:ENST00000521865.6(transcript)|ensembl:ENST00000522658.6(transcript)|ensembl:ENST00000522720.2(transcript)|ensembl:ENST00000523555.6(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008494""(translation activator activity)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031252""(cell leading edge)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0106002""(mCRD-mediated mRNA stability complex)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000623""(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034364|interpro:IPR035979|interpro:IPR036053|interpro:IPR045305|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|rcsb pdb:7BN3|rcsb pdb:8SMO|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9820841|reactome:R-HSA-9820865|panther:PTHR24012(orthology-group)|refseq:XP_005250918.1|dip:DIP-31613N"	"refseq:YP_002346320.1|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR050107|refseq:WP_002208803.1|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|panther:PTHR43790(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rogid:0VaVASVo0mvyDl5gKVp5uAy75QI632	intact-crc:45B23FF3B6FFC417|rigid:3SiGBTTX1b56N2h4yDiDzgHoTSQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W6D0	uniprotkb:P11940	intact:EBI-2862004|uniprotkb:Q74SF8|uniprotkb:Q0WCP0|uniprotkb:Q7CJH7|uniprotkb:A0A454XVI6|uniprotkb:A0A384KIW1	intact:EBI-81531|intact:EBI-28983164|uniprotkb:Q15097|uniprotkb:Q93004|ensembl:ENSP00000313007.5|ensembl:ENSP00000428749.2|ensembl:ENSP00000428840.2|ensembl:ENSP00000429119.2|ensembl:ENSP00000429790.2|ensembl:ENSP00000429892.2|ensembl:ENSP00000430012.2	psi-mi:a0a0h2w6d0_yerpe(display_long)|uniprotkb:YPO3028(locus name)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862008|imex:IM-13779-6699	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)|refseq:WP_002208523.1|interpro:IPR051551|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0009279""(cell outer membrane)|interpro:IPR036709|refseq:YP_002347948.1"	"refseq:NP_002559.2|ensembl:ENSG00000070756.17(gene)|ensembl:ENST00000318607.10(transcript)|ensembl:ENST00000520142.2(transcript)|ensembl:ENST00000520804.2(transcript)|ensembl:ENST00000521865.6(transcript)|ensembl:ENST00000522658.6(transcript)|ensembl:ENST00000522720.2(transcript)|ensembl:ENST00000523555.6(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008494""(translation activator activity)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031252""(cell leading edge)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0106002""(mCRD-mediated mRNA stability complex)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000623""(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034364|interpro:IPR035979|interpro:IPR036053|interpro:IPR045305|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|rcsb pdb:7BN3|rcsb pdb:8SMO|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9820841|reactome:R-HSA-9820865|panther:PTHR24012(orthology-group)|refseq:XP_005250918.1|dip:DIP-31613N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:W2gvcG57x1Q5nQ5vtCMffIM1uB8632	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:93897E8B7D406F03|rigid:JoJ8NSMlqFQxWKdRqai9YSwVP38	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9RI12	uniprotkb:Q9UNF0	intact:EBI-2849107|uniprotkb:O68717	intact:EBI-742503|uniprotkb:O95921|uniprotkb:Q96HV9|uniprotkb:Q9H0D3|uniprotkb:Q9NPN1|uniprotkb:Q9Y4V2|ensembl:ENSP00000263246.3|ensembl:ENSP00000385040.1|ensembl:ENSP00000385372.3	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	psi-mi:pacn2_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861983|imex:IM-13779-6702	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	"refseq:NP_001171899.1|refseq:NP_001171900.1|refseq:NP_009160.2|refseq:XP_005261376.1|ensembl:ENSG00000100266.19(gene)|ensembl:ENST00000263246.8(transcript)|ensembl:ENST00000402229.5(transcript)|ensembl:ENST00000403744.7(transcript)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0016607""(nuclear speck)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048858""(cell projection morphogenesis)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:0070836""(caveola assembly)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0097320""(plasma membrane tubulation)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9UNF0|rcsb pdb:3ABH|rcsb pdb:3ACO|rcsb pdb:3HAJ|rcsb pdb:3Q0K|reactome:R-HSA-8856828|refseq:XP_016884053.1|panther:PTHR23065(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	rogid:oEGsyQlsPg61RRGLjBdPGKDmkXc9606	intact-crc:197445281A7ACD82|rigid:sYQwSAMj+Rys7ujOe3Rt13XjaM4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UNF0	uniprotkb:Q8CZZ7	intact:EBI-742503|uniprotkb:O95921|uniprotkb:Q96HV9|uniprotkb:Q9H0D3|uniprotkb:Q9NPN1|uniprotkb:Q9Y4V2|ensembl:ENSP00000263246.3|ensembl:ENSP00000385040.1|ensembl:ENSP00000385372.3	intact:EBI-2842831|uniprotkb:Q74W48	psi-mi:pacn2_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym)	psi-mi:q8czz7_yerpe(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:YP_1051(locus name)|uniprotkb:y3075(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2861990|imex:IM-13779-6698	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001171899.1|refseq:NP_001171900.1|refseq:NP_009160.2|refseq:XP_005261376.1|ensembl:ENSG00000100266.19(gene)|ensembl:ENST00000263246.8(transcript)|ensembl:ENST00000402229.5(transcript)|ensembl:ENST00000403744.7(transcript)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008092""(cytoskeletal protein binding)|go:""GO:0016607""(nuclear speck)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0032587""(ruffle membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045296""(cadherin binding)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048858""(cell projection morphogenesis)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:0070836""(caveola assembly)|go:""GO:0072584""(caveolin-mediated endocytosis)|go:""GO:0097320""(plasma membrane tubulation)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9UNF0|rcsb pdb:3ABH|rcsb pdb:3ACO|rcsb pdb:3HAJ|rcsb pdb:3Q0K|reactome:R-HSA-8856828|refseq:XP_016884053.1|panther:PTHR23065(orthology-group)"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oEGsyQlsPg61RRGLjBdPGKDmkXc9606	rogid:5D57QZRbHjtu2izZZ+54f7spmuk632	intact-crc:A13E1C946A40F715|rigid:rKHUC8VzEfGmoukgi1Vz8e7iDFY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PIA6	uniprotkb:P11940	intact:EBI-2842908|uniprotkb:Q74VK3|uniprotkb:Q7CHE2|uniprotkb:A0A5P8YDR0|uniprotkb:A0A0H2W4I9	intact:EBI-81531|intact:EBI-28983164|uniprotkb:Q15097|uniprotkb:Q93004|ensembl:ENSP00000313007.5|ensembl:ENSP00000428749.2|ensembl:ENSP00000428840.2|ensembl:ENSP00000429119.2|ensembl:ENSP00000429790.2|ensembl:ENSP00000429892.2|ensembl:ENSP00000430012.2	psi-mi:a0a2s9pia6_yerpe(display_long)|uniprotkb:YPO1289(locus name)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862022|imex:IM-13779-6703	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011234(Fumarylacetoacetase, C-terminal-related)|refseq:WP_002208808.1|go:""GO:0003824""(catalytic activity)|go:""GO:0044281""(small molecule metabolic process)|interpro:IPR036663|refseq:YP_002346315.1|interpro:IPR051121"	"refseq:NP_002559.2|ensembl:ENSG00000070756.17(gene)|ensembl:ENST00000318607.10(transcript)|ensembl:ENST00000520142.2(transcript)|ensembl:ENST00000520804.2(transcript)|ensembl:ENST00000521865.6(transcript)|ensembl:ENST00000522658.6(transcript)|ensembl:ENST00000522720.2(transcript)|ensembl:ENST00000523555.6(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008494""(translation activator activity)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031252""(cell leading edge)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0106002""(mCRD-mediated mRNA stability complex)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000623""(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034364|interpro:IPR035979|interpro:IPR036053|interpro:IPR045305|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|rcsb pdb:7BN3|rcsb pdb:8SMO|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9820841|reactome:R-HSA-9820865|panther:PTHR24012(orthology-group)|refseq:XP_005250918.1|dip:DIP-31613N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:3/IrNkmiHMcBViQNlB32br606NM632	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:C341B86AF2660771|rigid:39yIPdzbRE6VZYlpk9hksJ3m/40	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11940	uniprotkb:A0A2S9PFE9	intact:EBI-81531|intact:EBI-28983164|uniprotkb:Q15097|uniprotkb:Q93004|ensembl:ENSP00000313007.5|ensembl:ENSP00000428749.2|ensembl:ENSP00000428840.2|ensembl:ENSP00000429119.2|ensembl:ENSP00000429790.2|ensembl:ENSP00000429892.2|ensembl:ENSP00000430012.2	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862029|imex:IM-13779-6706	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002559.2|ensembl:ENSG00000070756.17(gene)|ensembl:ENST00000318607.10(transcript)|ensembl:ENST00000520142.2(transcript)|ensembl:ENST00000520804.2(transcript)|ensembl:ENST00000521865.6(transcript)|ensembl:ENST00000522658.6(transcript)|ensembl:ENST00000522720.2(transcript)|ensembl:ENST00000523555.6(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008494""(translation activator activity)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031252""(cell leading edge)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0106002""(mCRD-mediated mRNA stability complex)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000623""(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034364|interpro:IPR035979|interpro:IPR036053|interpro:IPR045305|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|rcsb pdb:7BN3|rcsb pdb:8SMO|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9820841|reactome:R-HSA-9820865|panther:PTHR24012(orthology-group)|refseq:XP_005250918.1|dip:DIP-31613N"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	intact-crc:44D156FCD108F5A8|rigid:lkrbvk7wWEuB8Hz49DyMVB+9MtQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27986	uniprotkb:P17778	intact:EBI-79464|intact:EBI-28974553|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19|ensembl:ENSP00000428056.1|ensembl:ENSP00000429277.1|ensembl:ENSP00000513316.1|ensembl:ENSP00000513333.1	intact:EBI-2842665|uniprotkb:O68701	psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862055|imex:IM-13779-6707	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:3163""|efo:""Orphanet:33110""|efo:""Orphanet:397596""|panther:PTHR10155(orthology-group)|dip:DIP-119N|ensembl:ENST00000320694.13|ensembl:ENSP00000323512.8|ensembl:ENST00000336483.10|ensembl:ENSP00000338554.5|ensembl:ENSP00000513333.1|ensembl:ENSP00000428056.1|ensembl:ENSP00000429277.1|ensembl:ENST00000523872.1|ensembl:ENSP00000430098.1|ensembl:ENSP00000513316.1|ensembl:ENST00000697461.1|ensembl:ENSP00000513319.1|ensembl:ENST00000697467.1|ensembl:ENSP00000513325.1|interpro:IPR044124|ensembl:ENSG00000145675.16(gene)|ensembl:ENST00000517643.2(transcript)|ensembl:ENST00000521381.6(transcript)|ensembl:ENST00000521657.6(transcript)|ensembl:ENST00000697458.1(transcript)|go:""GO:0001678""(intracellular glucose homeostasis)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0001953""(negative regulation of cell-matrix adhesion)|go:""GO:0002687""(positive regulation of leukocyte migration)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005159""(insulin-like growth factor receptor binding)|go:""GO:0005168""(neurotrophin TRKA receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005942""(phosphatidylinositol 3-kinase complex)|go:""GO:0005943""(phosphatidylinositol 3-kinase complex, class IA)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006955""(immune response)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0016020""(membrane)|go:""GO:0019209""(kinase activator activity)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0033120""(positive regulation of RNA splicing)|go:""GO:0034143""(regulation of toll-like receptor 4 signaling pathway)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034644""(cellular response to UV)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035014""(phosphatidylinositol 3-kinase regulator activity)|go:""GO:0035655""(interleukin-18-mediated signaling pathway)|go:""GO:0036312""(phosphatidylinositol 3-kinase regulatory subunit binding)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043125""(ErbB-3 class receptor binding)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0043559""(insulin binding)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0046935""(1-phosphatidylinositol-3-kinase regulator activity)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|rcsb pdb:4L23|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0052742""(phosphatidylinositol kinase activity)|go:""GO:0060396""(growth hormone receptor signaling pathway)|go:""GO:0061470""(T follicular helper cell differentiation)|go:""GO:0097529""(myeloid leukocyte migration)|go:""GO:0120183""(positive regulation of focal adhesion disassembly)|go:""GO:0140767""(enzyme-substrate adaptor activity)|go:""GO:0141038""(phosphatidylinositol 3-kinase activator activity)|go:""GO:1900103""(positive regulation of endoplasmic reticulum unfolded protein response)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1990578""(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:2V1Y|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|rcsb pdb:5SX9|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|rcsb pdb:7CIO|rcsb pdb:7LM2|rcsb pdb:7LQ1|rcsb pdb:7MYN|rcsb pdb:7MYO|rcsb pdb:7PG5|rcsb pdb:7PG6|rcsb pdb:7RNS|rcsb pdb:7TZ7|rcsb pdb:8AM0|rcsb pdb:8DCP|rcsb pdb:8DCX|rcsb pdb:8DD4|rcsb pdb:8DD8|rcsb pdb:8GUB|rcsb pdb:8H36|rcsb pdb:8H37|rcsb pdb:8ILR|rcsb pdb:8ILS|rcsb pdb:8ILV|rcsb pdb:8SBC|rcsb pdb:8SBJ|rcsb pdb:8TDU|rcsb pdb:8TGD|rcsb pdb:8TS7|rcsb pdb:8TS8|rcsb pdb:8TS9|rcsb pdb:8TSA|rcsb pdb:8TSB|rcsb pdb:8TSC|rcsb pdb:8TSD|rcsb pdb:8TU6|rcsb pdb:8V8H|rcsb pdb:8V8I|rcsb pdb:8V8J|rcsb pdb:8V8U|rcsb pdb:8V8V|rcsb pdb:8W9A|rcsb pdb:8W9B|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-180292|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-198203|reactome:R-HSA-201556|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9680350|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9725370|reactome:R-HSA-983695|reactome:R-HSA-9842640|reactome:R-HSA-9842663|refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|refseq:XP_005248599.1|refseq:XP_016865074.1"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:537678CFC4FC172C|rigid:Q0ALfO6wImrcJT1AWwWY1USOHeY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11940	uniprotkb:A0A0H2W796	intact:EBI-81531|intact:EBI-28983164|uniprotkb:Q15097|uniprotkb:Q93004|ensembl:ENSP00000313007.5|ensembl:ENSP00000428749.2|ensembl:ENSP00000428840.2|ensembl:ENSP00000429119.2|ensembl:ENSP00000429790.2|ensembl:ENSP00000429892.2|ensembl:ENSP00000430012.2	intact:EBI-2862039|uniprotkb:Q74QN3|uniprotkb:Q7CGM2|uniprotkb:A0A380PLF2|uniprotkb:Q0WIR1	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:a0a0h2w796_yerpe(display_long)|uniprotkb:YPO0771(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862036|imex:IM-13779-6704	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002559.2|ensembl:ENSG00000070756.17(gene)|ensembl:ENST00000318607.10(transcript)|ensembl:ENST00000520142.2(transcript)|ensembl:ENST00000520804.2(transcript)|ensembl:ENST00000521865.6(transcript)|ensembl:ENST00000522658.6(transcript)|ensembl:ENST00000522720.2(transcript)|ensembl:ENST00000523555.6(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0008494""(translation activator activity)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0031252""(cell leading edge)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0070062""(extracellular exosome)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0106002""(mCRD-mediated mRNA stability complex)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000623""(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034364|interpro:IPR035979|interpro:IPR036053|interpro:IPR045305|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|rcsb pdb:7BN3|rcsb pdb:8SMO|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9820841|reactome:R-HSA-9820865|panther:PTHR24012(orthology-group)|refseq:XP_005250918.1|dip:DIP-31613N"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|refseq:WP_002214927.1|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR036640|refseq:YP_002345827.1|interpro:IPR039421"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rogid:LdBWXJ3vEq7kBJG8zGYQlpznRGM632	intact-crc:973258666843C0C9|rigid:Vqx2OXh8sQfpQa+z/K9gkp5bqCg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UQ80	uniprotkb:Q8ZHG7	intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886.6	intact:EBI-2843887|uniprotkb:Q0WIB0	psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym)	psi-mi:metk_yerpe(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:MAT(gene name synonym)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:YPO0931(locus name)|uniprotkb:y3314(locus name)|uniprotkb:YP_3512(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862048|imex:IM-13779-6705	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006182.2|ensembl:ENSG00000170515.14(gene)|ensembl:ENST00000303305.11(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006364""(rRNA processing)|go:""GO:0006417""(regulation of translation)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR018349|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|interpro:IPR047113|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:8K2C|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|reactome:R-HSA-6798695|dip:DIP-31275N|panther:PTHR10804(orthology-group)"	"interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|refseq:WP_002209971.1|refseq:YP_002345978.1|panther:PTHR11964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606	rogid:1htJOEwkQpME5HLtvSLlZmF2H0s632	intact-crc:7E188974BE5B9442|rigid:oENEbDMfnp7/J07nf78rDMlQPXY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WXI9	uniprotkb:Q7ARH3	intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644.4|ensembl:ENSP00000458280.1|ensembl:ENSP00000489184.1	intact:EBI-2849426|uniprotkb:A0A384KLR8|uniprotkb:O68711|uniprotkb:Q74YV0|uniprotkb:A0A0H2W092|uniprotkb:A0A2U2GVE2	psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym)	psi-mi:q7arh3_yerpe(display_long)|uniprotkb:tnpA(gene name)|psi-mi:tnpA(display_short)|uniprotkb:YPCD1.90c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862083|imex:IM-13779-6709	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143614.11(gene)|ensembl:ENSG00000261992.2(gene)|ensembl:ENST00000368655.5(transcript)|ensembl:ENST00000576342.2(transcript)|ensembl:ENST00000634544.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016581""(NuRD complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042659""(regulation of cell fate specification)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:2000736""(regulation of stem cell differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-9843940|reactome:R-HSA-9844594|reactome:R-HSA-9845323|refseq:NP_065750.1|refseq:XP_005245421.1|efo:""Orphanet:363686""|dip:DIP-36054N|ensembl:ENSP00000357644.4|ensembl:ENSP00000458280.1|ensembl:ENSP00000489184.1|panther:PTHR13455(orthology-group)"	"refseq:NP_857769.1|interpro:IPR002513(Transposase, Tn3)|refseq:NP_395219.1|interpro:IPR025296|interpro:IPR047653|refseq:WP_002213256.1|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606	rogid:00nBYkSaVEOjkb6Bm6Lk/llhQRc632	intact-crc:61A5519679CAED42|rigid:m3ja3VjqIFg0ox93uHY3RI9gRa0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1M8	uniprotkb:Q8WXI9	intact:EBI-2843956	intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644.4|ensembl:ENSP00000458280.1|ensembl:ENSP00000489184.1	psi-mi:q8d1m8_yerpe(display_long)|uniprotkb:y0257(locus name)	psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862062|imex:IM-13779-6712	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)|interpro:IPR050708	"ensembl:ENSG00000143614.11(gene)|ensembl:ENSG00000261992.2(gene)|ensembl:ENST00000368655.5(transcript)|ensembl:ENST00000576342.2(transcript)|ensembl:ENST00000634544.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016581""(NuRD complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042659""(regulation of cell fate specification)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:2000736""(regulation of stem cell differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-9843940|reactome:R-HSA-9844594|reactome:R-HSA-9845323|refseq:NP_065750.1|refseq:XP_005245421.1|efo:""Orphanet:363686""|dip:DIP-36054N|ensembl:ENSP00000357644.4|ensembl:ENSP00000458280.1|ensembl:ENSP00000489184.1|panther:PTHR13455(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:CV6eFVldIgYFQRKvjlqv9/IE4do632	rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606	intact-crc:29289EDAA4C92FDB|rigid:bZKUQaCOCls3ZPW5JYgB7Imq1Bw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WXI9	uniprotkb:Q8CLC4	intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644.4|ensembl:ENSP00000458280.1|ensembl:ENSP00000489184.1	intact:EBI-2844860	psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym)	psi-mi:q8clc4_yerpe(display_long)|uniprotkb:y1644(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862069|imex:IM-13779-6708	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143614.11(gene)|ensembl:ENSG00000261992.2(gene)|ensembl:ENST00000368655.5(transcript)|ensembl:ENST00000576342.2(transcript)|ensembl:ENST00000634544.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016581""(NuRD complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042659""(regulation of cell fate specification)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:2000736""(regulation of stem cell differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-9843940|reactome:R-HSA-9844594|reactome:R-HSA-9845323|refseq:NP_065750.1|refseq:XP_005245421.1|efo:""Orphanet:363686""|dip:DIP-36054N|ensembl:ENSP00000357644.4|ensembl:ENSP00000458280.1|ensembl:ENSP00000489184.1|panther:PTHR13455(orthology-group)"	interpro:IPR004375(Conserved hypothetical protein CHP00022)|interpro:IPR037012	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606	rogid:bRggnpBtWSjyBJTLgvdTftsIYl4632	intact-crc:887CE18DA75E1534|rigid:D+y0S7DALQV6VyBxxv7F0U/Qvuo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG0	uniprotkb:P04637	intact:EBI-2842527|uniprotkb:Q8CKL4|uniprotkb:Q0WIA2|uniprotkb:Q74QH2	intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5|ensembl:ENSP00000269305.4|ensembl:ENSP00000391478.2|ensembl:ENSP00000424104.2|ensembl:ENSP00000426252.2|ensembl:ENSP00000519624.1|ensembl:ENSP00000519626.1	psi-mi:agua_yerpe(display_long)|uniprotkb:aguA(gene name)|psi-mi:aguA(display_short)|uniprotkb:Agmatine iminohydrolase(gene name synonym)|uniprotkb:YPO0939(locus name)|uniprotkb:y3325(locus name)|uniprotkb:YP_3503(locus name)	psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862090|imex:IM-13779-6710	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017754(Agmatine deiminase)|interpro:IPR007466(Peptidyl-arginine deiminase, Porphyromonas-type)|go:""GO:0004668""(protein-arginine deiminase activity)|go:""GO:0009446""(putrescine biosynthetic process)|go:""GO:0047632""(agmatine deiminase activity)|refseq:YP_002345986.1|panther:PTHR31377(orthology-group)"	"efo:""Orphanet:1333""|efo:""Orphanet:145""|efo:""Orphanet:1501""|efo:""Orphanet:210159""|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:251899""|efo:""Orphanet:2807""|efo:""Orphanet:293199""|efo:""Orphanet:3318""|efo:""Orphanet:524""|efo:""Orphanet:585909""|efo:""Orphanet:668""|efo:""Orphanet:67038""|efo:""Orphanet:70573""|efo:""Orphanet:96253""|efo:""Orphanet:99756""|efo:""Orphanet:99757""|panther:PTHR11447(orthology-group)|efo:""Orphanet:52688""|ensembl:ENSG00000141510.19(gene)|ensembl:ENST00000269305.9(transcript)|ensembl:ENST00000445888.6(transcript)|ensembl:ENST00000503591.2(transcript)|ensembl:ENST00000508793.6(transcript)|ensembl:ENST00000714357.1(transcript)|ensembl:ENST00000714359.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000423""(mitophagy)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001094""(TFIID-class transcription factor complex binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001756""(somitogenesis)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0002020""(protease binding)|go:""GO:0002039""(p53 binding)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002309""(T cell proliferation involved in immune response)|go:""GO:0002326""(B cell lineage commitment)|go:""GO:0002360""(T cell lineage commitment)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005507""(copper ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005657""(replication fork)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006914""(autophagy)|go:""GO:0006974""(DNA damage response)|go:""GO:0006977""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:""GO:0006978""(obsolete DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:0006983""(ER overload response)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0007369""(gastrulation)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007406""(negative regulation of neuroblast proliferation)|go:""GO:0008104""(protein localization)|go:""GO:0008156""(negative regulation of DNA replication)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0009299""(mRNA transcription)|go:""GO:0009303""(rRNA transcription)|go:""GO:0009651""(response to salt stress)|go:""GO:0010165""(response to X-ray)|go:""GO:0010332""(response to gamma radiation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010659""(cardiac muscle cell apoptotic process)|go:""GO:0010666""(positive regulation of cardiac muscle cell apoptotic process)|go:""GO:0014009""(glial cell proliferation)|go:""GO:0016032""(viral process)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016605""(PML body)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019661""(glucose catabolic process to lactate via pyruvate)|go:""GO:0019899""(enzyme binding)|go:""GO:0021549""(cerebellum development)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034103""(regulation of tissue remodeling)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035033""(histone deacetylase regulator activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035794""(positive regulation of mitochondrial membrane permeability)|go:""GO:0035861""(site of double-strand break)|go:""GO:0036310""(ATP-dependent DNA/DNA annealing activity)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043073""(germ cell nucleus)|go:""GO:0043153""(entrainment of circadian clock by photoperiod)|go:""GO:0043504""(mitochondrial DNA repair)|go:""GO:0043516""(regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045899""(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0048512""(circadian behavior)|go:""GO:0048539""(bone marrow development)|go:""GO:0048568""(embryonic organ development)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051097""(negative regulation of helicase activity)|go:""GO:0051262""(protein tetramerization)|go:""GO:0051276""(chromosome organization)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0062100""(positive regulation of programmed necrotic cell death)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070242""(thymocyte apoptotic process)|go:""GO:0070245""(positive regulation of thymocyte apoptotic process)|go:""GO:0070266""(necroptotic process)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071494""(cellular response to UV-C)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0072331""(signal transduction by p53 class mediator)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0072717""(cellular response to actinomycin D)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090399""(replicative senescence)|go:""GO:0090403""(oxidative stress-induced premature senescence)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097252""(oligodendrocyte apoptotic process)|go:""GO:0097371""(MDM2/MDM4 family protein binding)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1901525""(negative regulation of mitophagy)|go:""GO:1902108""(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:""GO:1902253""(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:1902749""(regulation of cell cycle G2/M phase transition)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903451""(negative regulation of G1 to G0 transition)|go:""GO:1903799""(negative regulation of miRNA processing)|go:""GO:1904024""(negative regulation of glucose catabolic process to lactate via pyruvate)|go:""GO:1905856""(negative regulation of pentose-phosphate shunt)|go:""GO:1990144""(intrinsic apoptotic signaling pathway in response to hypoxia)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000269""(regulation of fibroblast apoptotic process)|go:""GO:2000378""(negative regulation of reactive oxygen species metabolic process)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|go:""GO:2000647""(negative regulation of stem cell proliferation)|go:""GO:2000774""(positive regulation of cellular senescence)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872(""p53 transactivation domain (TAD)"")|interpro:IPR036674|interpro:IPR040926|mint:P04637|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|rcsb pdb:2AHI|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3Q06|rcsb pdb:3SAK|rcsb pdb:3TG5|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGL|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:5BUA|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6XRE|rcsb pdb:6ZNC|rcsb pdb:7B46|rcsb pdb:7B47|rcsb pdb:7B48|rcsb pdb:7B49|rcsb pdb:7B4A|rcsb pdb:7B4B|rcsb pdb:7B4C|rcsb pdb:7B4D|rcsb pdb:7B4E|rcsb pdb:7B4F|rcsb pdb:7B4G|rcsb pdb:7B4H|rcsb pdb:7B4N|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7DVD|rcsb pdb:7EAX|rcsb pdb:7EDS|rcsb pdb:7EEU|rcsb pdb:7EL4|rcsb pdb:7NMI|rcsb pdb:7RM4|rcsb pdb:7V97|rcsb pdb:7XZX|rcsb pdb:7XZZ|rcsb pdb:7YGI|rcsb pdb:8A31|rcsb pdb:8A32|rcsb pdb:8A92|rcsb pdb:8CG7|rcsb pdb:8DC4|rcsb pdb:8DC6|rcsb pdb:8DC7|rcsb pdb:8DC8|rcsb pdb:8E7A|rcsb pdb:8E7B|rcsb pdb:8F2H|rcsb pdb:8F2I|rcsb pdb:8GCR|rcsb pdb:8HLL|rcsb pdb:8HLM|rcsb pdb:8HLN|rcsb pdb:8J8N|rcsb pdb:8OXM|rcsb pdb:8OXO|rcsb pdb:8QWK|rcsb pdb:8QWL|rcsb pdb:8QWM|rcsb pdb:8QWN|rcsb pdb:8QWO|rcsb pdb:8QWP|rcsb pdb:8R1F|rcsb pdb:8R1G|rcsb pdb:8UQR|rcsb pdb:8WD2|rcsb pdb:8XP5|rcsb pdb:9C5S|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-9723905|reactome:R-HSA-9725370|reactome:R-HSA-9758274|reactome:R-HSA-9819196|reactome:R-HSA-983231|reactome:R-HSA-9833482|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|refseq:NP_001119590.1|refseq:NP_001263624.1|refseq:NP_001263625.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|ensembl:ENSP00000269305.4|ensembl:ENST00000420246.6|ensembl:ENSP00000391127.2|ensembl:ENSP00000391478.2|ensembl:ENST00000455263.6|ensembl:ENSP00000398846.2|ensembl:ENSP00000426252.2|ensembl:ENST00000504290.5|ensembl:ENSP00000484409.1|ensembl:ENST00000504937.5|ensembl:ENSP00000481179.1|ensembl:ENSP00000424104.2|ensembl:ENST00000509690.6|ensembl:ENSP00000425104.2|ensembl:ENST00000510385.5|ensembl:ENSP00000478499.1|ensembl:ENST00000610292.4|ensembl:ENSP00000478219.1|ensembl:ENST00000610538.4|ensembl:ENSP00000480868.1|ensembl:ENST00000619485.4|ensembl:ENSP00000482537.1|ensembl:ENST00000620739.4|ensembl:ENSP00000481638.1|ensembl:ENST00000622645.4|ensembl:ENSP00000482222.1|ensembl:ENSP00000519624.1|ensembl:ENSP00000519626.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:wqVmguxc+OwAcDUbyMd1UcCWH/o632	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	intact-crc:85A16831E56CF812|rigid:SrPMpo8IxOmwCjQqvSpvVvxMjng	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WXI9	uniprotkb:A0A0H2W0I2	intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644.4|ensembl:ENSP00000458280.1|ensembl:ENSP00000489184.1	intact:EBI-2847735|uniprotkb:Q74XP3|uniprotkb:Q0WBW4|uniprotkb:Q7CKA9|uniprotkb:A0A384L3M8	psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym)	psi-mi:a0a0h2w0i2_yerpe(display_long)|uniprotkb:YPO3328(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862076|imex:IM-13779-6711	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143614.11(gene)|ensembl:ENSG00000261992.2(gene)|ensembl:ENST00000368655.5(transcript)|ensembl:ENST00000576342.2(transcript)|ensembl:ENST00000634544.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016581""(NuRD complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042659""(regulation of cell fate specification)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:2000736""(regulation of stem cell differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-9843940|reactome:R-HSA-9844594|reactome:R-HSA-9845323|refseq:NP_065750.1|refseq:XP_005245421.1|efo:""Orphanet:363686""|dip:DIP-36054N|ensembl:ENSP00000357644.4|ensembl:ENSP00000458280.1|ensembl:ENSP00000489184.1|panther:PTHR13455(orthology-group)"	"interpro:IPR025997|interpro:IPR028082|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002348224.1|interpro:IPR050555"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606	rogid:HHGoonb2nUNXAajQaaTnNuqKf7g632	intact-crc:0C29C58BC9AAE86F|rigid:EOXe8Iv/ryKNdm0liVIfxKAsUhk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W6D0	uniprotkb:Q01804	intact:EBI-2862004|uniprotkb:Q74SF8|uniprotkb:Q0WCP0|uniprotkb:Q7CJH7|uniprotkb:A0A454XVI6|uniprotkb:A0A384KIW1	intact:EBI-1054396|uniprotkb:Q147U2|uniprotkb:Q1ZYK1|uniprotkb:Q6PG39|uniprotkb:Q96MQ5|uniprotkb:Q9NT94|uniprotkb:Q9UPV6|uniprotkb:B4DYS4|ensembl:ENSP00000395487.2	psi-mi:a0a0h2w6d0_yerpe(display_long)|uniprotkb:YPO3028(locus name)	psi-mi:otud4_human(display_long)|uniprotkb:HIN-1(gene name synonym)|uniprotkb:HIV-1-induced protein HIN-1(gene name synonym)|uniprotkb:OTUD4(gene name)|psi-mi:OTUD4(display_short)|uniprotkb:KIAA1046(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862137|imex:IM-13779-6717	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)|refseq:WP_002208523.1|interpro:IPR051551|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0009279""(cell outer membrane)|interpro:IPR036709|refseq:YP_002347948.1"	"refseq:XP_005263136.1|refseq:NP_001096123.1|refseq:NP_059963.1|ensembl:ENSG00000164164.17(gene)|ensembl:ENST00000447906.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006307""(DNA alkylation repair)|go:""GO:0006508""(proteolysis)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0035871""(protein K11-linked deubiquitination)|go:""GO:0045087""(innate immune response)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061578""(K63-linked deubiquitinase activity)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:1903093""(regulation of protein K48-linked deubiquitination)|go:""GO:2000660""(negative regulation of interleukin-1-mediated signaling pathway)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR038765|interpro:IPR050704|mint:Q01804|panther:PTHR12419(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:W2gvcG57x1Q5nQ5vtCMffIM1uB8632	rogid:humMGfho0HKWE4zhO7+G00gIJfc9606	intact-crc:4C065F252408596B|rigid:7J//qVHiRJNx9VVgjVkw6INyl8E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8Z9U1	uniprotkb:Q96HP4	intact:EBI-2862117|uniprotkb:Q74PB4|uniprotkb:Q0W9T3|uniprotkb:Q7CFN5	intact:EBI-2862111|uniprotkb:Q2HYC7|uniprotkb:Q59FA4|ensembl:ENSP00000285083.5|ensembl:ENSP00000475547.1	psi-mi:fabv_yerpe(display_long)|uniprotkb:fabV(gene name)|psi-mi:fabV(display_short)|uniprotkb:YPO4104(locus name)|uniprotkb:YP_4011(locus name)|uniprotkb:y4119(locus name)	psi-mi:oxnd1_human(display_long)|uniprotkb:OXNAD1(gene name)|psi-mi:OXNAD1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862123|imex:IM-13779-6714	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:4BKQ|interpro:IPR010758(Short-chain alcohol dehydrogenase)|interpro:IPR024906|interpro:IPR024910|rcsb pdb:3ZU2|rcsb pdb:3ZU3|rcsb pdb:3ZU4|rcsb pdb:3ZU5|rcsb pdb:5JAI|rcsb pdb:5JAM|rcsb pdb:5JAQ|refseq:WP_002215588.1|interpro:IPR050048|go:""GO:0004318""(""enoyl-[acyl-carrier-protein] reductase (NADH) activity"")|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0050343""(""trans-2-enoyl-CoA reductase (NADH) activity"")|go:""GO:0051287""(NAD binding)|rcsb pdb:5G2O|refseq:YP_002348955.1|panther:PTHR37480(orthology-group)"	"refseq:XP_016862975.1|refseq:XP_016862976.1|refseq:XP_016862977.1|refseq:XP_016862978.1|refseq:XP_016862979.1|refseq:XP_016862980.1|refseq:XP_016862981.1|refseq:NP_612390.1|ensembl:ENSG00000154814.14(gene)|ensembl:ENST00000285083.10(transcript)|ensembl:ENST00000605932.5(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|interpro:IPR052128|panther:PTHR46505(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6xpFFSeTcjjzoLCZJGHi3G1YstE632	rogid:YoyEZZbd3hRDTYfrtt1tqEs2t289606	intact-crc:1C797DA8B961EEA4|rigid:aCkzuF0wjuIJtD+y1FRUVbnGCiw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00443	uniprotkb:Q8D0H2	intact:EBI-641094|uniprotkb:Q14CQ9|uniprotkb:B0LPH2|ensembl:ENSP00000265970.6|ensembl:ENSP00000509400.1|uniprotkb:B4E2G4	intact:EBI-2852758|uniprotkb:Q74TR1	psi-mi:p3c2a_human(display_long)|uniprotkb:Phosphoinositide 3-kinase-C2-alpha(gene name synonym)|uniprotkb:PIK3C2A(gene name)|psi-mi:PIK3C2A(display_short)	psi-mi:q8d0h2_yerpe(display_long)|uniprotkb:y2130(locus name)|uniprotkb:phoA(gene name)|psi-mi:phoA(display_short)|uniprotkb:YP_2083(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862104|imex:IM-13779-6716	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000011405.14(gene)|ensembl:ENST00000265970.11(transcript)|ensembl:ENST00000691414.1(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0006887""(exocytosis)|go:""GO:0006897""(endocytosis)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0014829""(vascular associated smooth muscle contraction)|go:""GO:0016020""(membrane)|go:""GO:0016303""(1-phosphatidylinositol-3-kinase activity)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030276""(clathrin binding)|go:""GO:0031982""(vesicle)|go:""GO:0035005""(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036092""(phosphatidylinositol-3-phosphate biosynthetic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0046934""(1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048015""(phosphatidylinositol-mediated signaling)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0061024""(membrane organization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR001683(Phox-like)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036871|interpro:IPR036940|interpro:IPR037705|interpro:IPR042133|interpro:IPR042236|mint:O00443|rcsb pdb:2AR5|rcsb pdb:2IWL|rcsb pdb:2REA|rcsb pdb:2RED|rcsb pdb:6BTY|rcsb pdb:6BTZ|rcsb pdb:6BU0|rcsb pdb:6BUB|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-432722|reactome:R-HSA-8856828|refseq:NP_001308307.1|refseq:NP_002636.2|refseq:XP_016873413.1|dip:DIP-33727N|efo:""Orphanet:557003""|panther:PTHR10048(orthology-group)"	"interpro:IPR001952(Alkaline phosphatase)|interpro:IPR018299|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|go:""GO:0016791""(phosphatase activity)|go:""GO:0046872""(metal ion binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/28	rogid:etm4OwWiGBZtmarHi94o8yW9js89606	rogid:KhjfklmVQA9OcvPoJfuat/W+MmY632	intact-crc:37B401E0922A6D33|rigid:cE7Sekjygs1tbbMhWf0Yp7y/Wcs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0D4	uniprotkb:Q96HP4	intact:EBI-2847212	intact:EBI-2862111|uniprotkb:Q2HYC7|uniprotkb:Q59FA4|ensembl:ENSP00000285083.5|ensembl:ENSP00000475547.1	psi-mi:q8d0d4_yerpe(display_long)|uniprotkb:hmsH(gene name)|psi-mi:hmsH(display_short)|uniprotkb:y2359(locus name)	psi-mi:oxnd1_human(display_long)|uniprotkb:OXNAD1(gene name)|psi-mi:OXNAD1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862130|imex:IM-13779-6715	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023870|interpro:IPR011990(Tetratricopeptide-like helical)|go:""GO:1901515""(poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity)|interpro:IPR049003"	"refseq:XP_016862975.1|refseq:XP_016862976.1|refseq:XP_016862977.1|refseq:XP_016862978.1|refseq:XP_016862979.1|refseq:XP_016862980.1|refseq:XP_016862981.1|refseq:NP_612390.1|ensembl:ENSG00000154814.14(gene)|ensembl:ENST00000285083.10(transcript)|ensembl:ENST00000605932.5(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|interpro:IPR052128|panther:PTHR46505(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oBs/IRM9/gKecuXNw9IoCZLu4Vw632	rogid:YoyEZZbd3hRDTYfrtt1tqEs2t289606	intact-crc:E4477716B84B7D8D|rigid:huirQoseFsiG5xgwxMDKCZ7oBc0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IVL5	uniprotkb:A0A2U2GYH3	intact:EBI-2828235|uniprotkb:B3KWI9|uniprotkb:Q9NVI2|uniprotkb:B3KPK0|uniprotkb:D3DNV8|ensembl:ENSP00000316881.5	intact:EBI-2842340|uniprotkb:Q74PE3|uniprotkb:Q0W9X2|uniprotkb:Q7CFQ3|uniprotkb:A0A5P8YAI4|uniprotkb:A0A384L096	psi-mi:p3h2_human(display_long)|uniprotkb:P3H2(gene name)|psi-mi:P3H2(display_short)|uniprotkb:LEPREL1(gene name synonym)|uniprotkb:Leprecan-like protein 1(gene name synonym)|uniprotkb:MLAT4(gene name synonym)|uniprotkb:Myxoid liposarcoma-associated protein 4(gene name synonym)	psi-mi:a0a2u2gyh3_yerpe(display_long)|uniprotkb:fdoH(gene name)|psi-mi:fdoH(display_short)|uniprotkb:YPO4057(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862097|imex:IM-13779-6713	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:98619""|ensembl:ENSG00000090530.10(gene)|ensembl:ENST00000319332.10(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019511""(peptidyl-proline hydroxylation)|go:""GO:0019797""(procollagen-proline 3-dioxygenase activity)|go:""GO:0031418""(L-ascorbic acid binding)|go:""GO:0032963""(collagen metabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|interpro:IPR005123(""2OG-Fe(II) oxygenase"")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR039575|interpro:IPR044862|reactome:R-HSA-1650814|refseq:NP_001127890.1|refseq:NP_060662.2|refseq:XP_011511257.1|panther:PTHR14049(orthology-group)"	"interpro:IPR017896|interpro:IPR006470(Formate dehydrogenase, beta subunit)|interpro:IPR014603(Formate dehydrogenase, iron-sulphur subunit)|interpro:IPR015246(Formate dehydrogenase, transmembrane)|interpro:IPR017900|go:""GO:0005886""(plasma membrane)|go:""GO:0015944""(formate oxidation)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002209611.1|interpro:IPR038384|refseq:YP_002348916.1|interpro:IPR051555"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:w99/605+HFG15N85XEo/KgBm+RM9606	rogid:qUnsGukyBMEHq2jL5PYOvQ0betE632	intact-crc:F722EDF077F37FAD|rigid:39ozlew7m15qquieYpC0sJivepU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92882	uniprotkb:Q8CLT0	intact:EBI-1051152|uniprotkb:Q5W126|uniprotkb:Q96IJ4|ensembl:ENSP00000340836.6	intact:EBI-2855052|uniprotkb:Q74PF1	psi-mi:ostf1_human(display_long)|uniprotkb:OSTF1(gene name)|psi-mi:OSTF1(display_short)	psi-mi:q8clt0_yerpe(display_long)|uniprotkb:YP_3956(locus name)|uniprotkb:y0280(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862159|imex:IM-13779-6721	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036515.4|ensembl:ENSG00000134996.12(gene)|ensembl:ENST00000346234.7(transcript)|go:""GO:0001503""(ossification)|go:""GO:0005576""(extracellular region)|go:""GO:0007165""(signal transduction)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0034774""(secretory granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR036028|interpro:IPR036770|mint:Q92882|rcsb pdb:1X2K|rcsb pdb:1ZLM|rcsb pdb:3EHQ|rcsb pdb:3EHR|reactome:R-HSA-6798695|panther:PTHR24155(orthology-group)"	interpro:IPR010732(Protein of unknown function DUF1305)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0nz6SBCE9meig3C9vDuhLZTIq2s9606	rogid:YJLIYYyJ4C5Tki3xmcQ2jFOW6ig632	intact-crc:919F565B93EB7CE2|rigid:2Z2aztMR2NaGNRmE39W3J8Ll+RI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5VV17	uniprotkb:Q8ZGJ9	intact:EBI-2510778|ensembl:ENSP00000365678.3	intact:EBI-2845469|uniprotkb:Q8D025|uniprotkb:Q0WHC0	psi-mi:otud1_human(display_long)|uniprotkb:OTUD1(gene name)|psi-mi:OTUD1(display_short)|uniprotkb:DUBA7(gene name synonym)|uniprotkb:OTDC1(gene name synonym)|uniprotkb:DUBA-7(gene name synonym)	psi-mi:rpia2_yerpe(display_long)|uniprotkb:rpiA2(gene name)|psi-mi:rpiA2(display_short)|uniprotkb:Phosphoriboisomerase A 2(gene name synonym)|uniprotkb:YPO1292(locus name)|uniprotkb:y2892(locus name)|uniprotkb:YP_1299(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862144|imex:IM-13779-6722	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138845.1|mint:Q5VV17|rcsb pdb:4BOP|ensembl:ENSG00000165312.7(gene)|ensembl:ENST00000376495.5(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0070536""(protein K63-linked deubiquitination)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR038765|interpro:IPR047834|interpro:IPR050704|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|panther:PTHR12419(orthology-group)"	"interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|go:""GO:0004751""(ribose-5-phosphate isomerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006014""(D-ribose metabolic process)|go:""GO:0009052""(pentose-phosphate shunt, non-oxidative branch)|interpro:IPR037171|refseq:WP_002208805.1|refseq:YP_002346318.1|panther:PTHR11934(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BISOnPKUXNIZ+cNVrtvnKJpw3sA9606	rogid:sddl00uN3G2aI0Hh5UEuroM7EKU632	intact-crc:DAB4802883C4BE91|rigid:HqOhGJDjOjcal0JjYzK6qQfyDmc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5VV17	uniprotkb:A0A2S9PJE2	intact:EBI-2510778|ensembl:ENSP00000365678.3	intact:EBI-2850829|uniprotkb:Q74WU5|uniprotkb:Q0WC89|uniprotkb:Q7CK47|uniprotkb:A0A384L2F1	psi-mi:otud1_human(display_long)|uniprotkb:OTUD1(gene name)|psi-mi:OTUD1(display_short)|uniprotkb:DUBA7(gene name synonym)|uniprotkb:OTDC1(gene name synonym)|uniprotkb:DUBA-7(gene name synonym)	psi-mi:a0a2s9pje2_yerpe(display_long)|uniprotkb:ahpC(gene name)|psi-mi:ahpC(display_short)|uniprotkb:YPO3194(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862151|imex:IM-13779-6718	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138845.1|mint:Q5VV17|rcsb pdb:4BOP|ensembl:ENSG00000165312.7(gene)|ensembl:ENST00000376495.5(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0070536""(protein K63-linked deubiquitination)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR038765|interpro:IPR047834|interpro:IPR050704|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|panther:PTHR12419(orthology-group)"	"interpro:IPR013766(Thioredoxin domain)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|refseq:WP_002208675.1|go:""GO:0005829""(cytosol)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0045454""(cell redox homeostasis)|interpro:IPR036249|refseq:YP_002348099.1|interpro:IPR050217|panther:PTHR10681(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BISOnPKUXNIZ+cNVrtvnKJpw3sA9606	rogid:GnZEc/ZzTTpq4nrPnH46z4CNIwg632	intact-crc:41D758A5FA980757|rigid:OQtGWB/filiZR7UsDUOhH0PfY58	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG7	uniprotkb:Q96SU4	intact:EBI-2843887|uniprotkb:Q0WIB0	intact:EBI-2511368|ensembl:ENSP00000407168.1|uniprotkb:Q6IA67|uniprotkb:Q9H9X2|uniprotkb:Q96SK4|uniprotkb:B1AKJ8|uniprotkb:Q5TFC0|uniprotkb:Q8NB17|uniprotkb:Q8TAS8|uniprotkb:D3DQ31|uniprotkb:B3KPQ4|uniprotkb:Q86YQ3	psi-mi:metk_yerpe(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:MAT(gene name synonym)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:YPO0931(locus name)|uniprotkb:y3314(locus name)|uniprotkb:YP_3512(locus name)	psi-mi:osbl9_human(display_long)|uniprotkb:OSBPL9(gene name)|psi-mi:OSBPL9(display_short)|uniprotkb:ORP9(gene name synonym)|uniprotkb:OSBP4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862173|imex:IM-13779-6720	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|refseq:WP_002209971.1|refseq:YP_002345978.1|panther:PTHR11964(orthology-group)"	"ensembl:ENSG00000117859.19(gene)|ensembl:ENST00000428468.6(transcript)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032934""(sterol binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0120015""(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q96SU4|reactome:R-HSA-192105|refseq:XP_011538905.1|refseq:XP_011538906.1|refseq:NP_078862.4|refseq:NP_683702.1|refseq:NP_683703.1|refseq:NP_683705.1|refseq:NP_683706.3|refseq:NP_683704.2|refseq:NP_683707.3|refseq:XP_006710386.1|refseq:XP_006710387.1|refseq:XP_006710388.1|refseq:XP_006710389.1|refseq:NP_001317509.1|refseq:XP_016855708.1|refseq:XP_016855709.1|refseq:XP_016855710.1|panther:PTHR10972(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1htJOEwkQpME5HLtvSLlZmF2H0s632	rogid:2XLQ0JD4BEKGoyiwd/63YTmyVlE9606	intact-crc:7B4301DD109B03F5|rigid:38hqcHbxj2eiqtzFR+od721lz1s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6M0NNK5	uniprotkb:Q8IYS5	intact:EBI-2846580	intact:EBI-2815934|uniprotkb:Q8NHL4|uniprotkb:Q8WXQ1|uniprotkb:Q8WXQ0|uniprotkb:Q8WXQ2|uniprotkb:Q8N763|uniprotkb:Q5GRG5|uniprotkb:B7WNS2|ensembl:ENSP00000365808.2|ensembl:ENSP00000375641.1|ensembl:ENSP00000478216.1|ensembl:ENSP00000479628.1|ensembl:ENSP00000480193.1|ensembl:ENSP00000480863.1|ensembl:ENSP00000480900.1|ensembl:ENSP00000481257.1|ensembl:ENSP00000481647.1|ensembl:ENSP00000481785.1|ensembl:ENSP00000482414.1|ensembl:ENSP00000484323.1	psi-mi:a0a6m0nnk5_yerpe(display_long)|uniprotkb:y1846(locus name)	psi-mi:oscar_human(display_long)|uniprotkb:OSCAR(gene name)|psi-mi:OSCAR(display_short)|uniprotkb:Polymeric immunoglobulin receptor 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862166|imex:IM-13779-6719	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T7I9(uniprot-removed-ac)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR008640(Hep/Hag)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0019867""(outer membrane)"	"refseq:NP_001269278.1|refseq:NP_001269279.1|refseq:NP_570127.3|refseq:NP_573398.2|refseq:NP_573399.2|refseq:NP_996554.2|ensembl:ENSG00000170909.14(gene)|ensembl:ENSG00000273511.4(gene)|ensembl:ENSG00000274703.4(gene)|ensembl:ENSG00000275551.4(gene)|ensembl:ENSG00000275644.4(gene)|ensembl:ENSG00000275736.4(gene)|ensembl:ENSG00000276982.4(gene)|ensembl:ENSG00000277088.4(gene)|ensembl:ENSG00000278378.4(gene)|ensembl:ENSG00000278533.4(gene)|ensembl:ENST00000284648.10(transcript)|ensembl:ENST00000391761.5(transcript)|ensembl:ENST00000611480.4(transcript)|ensembl:ENST00000612289.4(transcript)|ensembl:ENST00000613426.4(transcript)|ensembl:ENST00000614003.4(transcript)|ensembl:ENST00000616215.4(transcript)|ensembl:ENST00000616758.4(transcript)|ensembl:ENST00000617622.4(transcript)|ensembl:ENST00000618710.4(transcript)|ensembl:ENST00000620647.4(transcript)|ensembl:ENST00000622326.4(transcript)|go:""GO:0002764""(immune response-regulating signaling pathway)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0035580""(specific granule lumen)|go:""GO:0038064""(collagen receptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904724""(tertiary granule lumen)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050412|rcsb pdb:5CJ8|rcsb pdb:5CJB|rcsb pdb:5EIQ|rcsb pdb:5EIV|reactome:R-HSA-198933|reactome:R-HSA-6798695|panther:PTHR11738(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yL2m6VTkA9R9Q4e4kurjcWXhQOY632	rogid:HPVkH87m2Sz3iyHQ82BhWO0Grzw9606	intact-crc:49CD04B8EE08E41B|rigid:TU9s+fGNlv/dGoH2EDGbl1Onpko	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PJN0	uniprotkb:Q96SN7	intact:EBI-2848458|uniprotkb:Q74XE8|uniprotkb:A0A0H2W321|uniprotkb:Q7CKP0|uniprotkb:A0A384KEH5	intact:EBI-714817|uniprotkb:Q6IA68|uniprotkb:Q8WY94|uniprotkb:Q9H9Y3|ensembl:ENSP00000348752.2|ensembl:ENSP00000385489.3|ensembl:ENSP00000417928.1|ensembl:ENSP00000418140.1|ensembl:ENSP00000418464.2|ensembl:ENSP00000420178.2|ensembl:ENSP00000478113.1	psi-mi:a0a2s9pjn0_yerpe(display_long)|uniprotkb:YPO0327(locus name)	psi-mi:orai2_human(display_long)|uniprotkb:TMEM142B(gene name synonym)|uniprotkb:ORAI2(gene name)|psi-mi:ORAI2(display_short)|uniprotkb:PP1729(orf name)|uniprotkb:C7orf19(gene name synonym)|uniprotkb:CBCIP2(gene name synonym)|uniprotkb:CAP-binding protein complex-interacting protein 2(gene name synonym)|uniprotkb:Transmembrane protein 142B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862187|imex:IM-13779-6726	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001670(Iron-containing alcohol dehydrogenase)|interpro:IPR013460(Lactaldehyde reductase)|interpro:IPR018211|refseq:WP_002209102.1|go:""GO:0004022""(""alcohol dehydrogenase (NAD+) activity"")|go:""GO:0046872""(metal ion binding)|go:""GO:0050093""(""methanol dehydrogenase (NAD+) activity"")|interpro:IPR039697|refseq:YP_002345407.1|panther:PTHR11496(orthology-group)"	"refseq:NP_001119812.1|refseq:NP_116220.1|refseq:NP_001258747.1|ensembl:ENSG00000160991.17(gene)|ensembl:ENST00000356387.6(transcript)|ensembl:ENST00000403646.8(transcript)|ensembl:ENST00000473939.2(transcript)|ensembl:ENST00000478730.7(transcript)|ensembl:ENST00000495936.7(transcript)|ensembl:ENST00000498661.6(transcript)|ensembl:ENST00000611770.5(transcript)|go:""GO:0002115""(store-operated calcium entry)|go:""GO:0005886""(plasma membrane)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0016020""(membrane)|go:""GO:0030426""(growth cone)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-48944N|panther:PTHR31501(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:a5XWJKRLg8L6JLHmBu7QTvqa0u0632	rogid:vch80zTIaj1OmGLhPD6/mUe6a749606	intact-crc:59B504949D2FF97F|rigid:7v+aLzIB54UxgzJ/pJHNpR0L618	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q02218	uniprotkb:Q8ZJF3	intact:EBI-747213|intact:EBI-1210683|uniprotkb:Q9UDX0|ensembl:ENSP00000222673.5|uniprotkb:D3DVL0|uniprotkb:B4E2U9|uniprotkb:E9PBM1|uniprotkb:Q96DD3	intact:EBI-2850095|uniprotkb:Q0WKE6	"psi-mi:odo1_human(display_long)|uniprotkb:OGDH(gene name)|psi-mi:OGDH(display_short)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase, mitochondrial(gene name synonym)|uniprotkb:""Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase""(gene name synonym)"	psi-mi:gph_yerpe(display_long)|uniprotkb:gph(gene name)|psi-mi:gph(display_short)|uniprotkb:YPO0156(locus name)|uniprotkb:y3939(locus name)|uniprotkb:YP_0158(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862194|imex:IM-13779-6724	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105953.16(gene)|ensembl:ENST00000222673.6(transcript)|go:""GO:0004591""(""oxoglutarate dehydrogenase (succinyl-transferring) activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0006096""(glycolytic process)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0006104""(succinyl-CoA metabolic process)|go:""GO:0021695""(cerebellar cortex development)|go:""GO:0021756""(striatum development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021794""(thalamus development)|go:""GO:0021860""(pyramidal neuron development)|go:""GO:0022028""(tangential migration from the subventricular zone to the olfactory bulb)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034602""(""oxoglutarate dehydrogenase (NAD+) activity"")|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0061034""(olfactory bulb mitral cell layer development)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|mint:Q02218|rcsb pdb:3ERY|rcsb pdb:7WGR|rcsb pdb:8I0K|reactome:R-HSA-6783984|reactome:R-HSA-9837999|reactome:R-HSA-9853506|refseq:NP_001003941.1|refseq:NP_001158508.1|refseq:NP_002532.2|efo:""Orphanet:31""|dip:DIP-39353N|panther:PTHR23152(orthology-group)"	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|interpro:IPR037512|refseq:WP_002208892.1|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006281""(DNA repair)|go:""GO:0008967""(phosphoglycolate phosphatase activity)|go:""GO:0046295""(glycolate biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR036412|interpro:IPR041492|refseq:YP_002345242.1|interpro:IPR050155|panther:PTHR43434(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:B9CSRCmhDYg7n5jSpuDlr2mrxDg9606	rogid:n2m9iPEoLBOpfauijcWx/W/lq+M632	intact-crc:D26779B1AE0CB3BB|rigid:/337BNrQPLkuzyT4RfU2SSKc8w4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VBG2	uniprotkb:Q9ULJ1	intact:EBI-2849663	intact:EBI-715823|intact:EBI-2558792|uniprotkb:Q05C40|uniprotkb:Q5BJG5|uniprotkb:Q5TBX3|uniprotkb:Q5TBX4|uniprotkb:Q86X31|uniprotkb:A8MU56|uniprotkb:B4E037|ensembl:ENSP00000320165.8|ensembl:ENSP00000359600.2	psi-mi:a0a6b3vbg2_yerpe(display_long)|uniprotkb:yapB(gene name)|psi-mi:yapB(display_short)|uniprotkb:y1345(locus name)	psi-mi:odf2l_human(display_long)|uniprotkb:KIAA1229(gene name synonym)|uniprotkb:BCAP(gene name synonym)|uniprotkb:Basal body centriole-associated protein(gene name synonym)|uniprotkb:Outer dense fiber protein 2-like(gene name synonym)|uniprotkb:ODF2L(gene name)|psi-mi:ODF2L(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862208|imex:IM-13779-6727	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|uniprotkb:A0A6B3T6Y5(uniprot-removed-ac)|go:""GO:0019867""(outer membrane)|interpro:IPR051551"	"refseq:XP_005271111.1|refseq:NP_001007023.2|refseq:NP_001171694.1|refseq:NP_001171695.1|refseq:NP_065780.2|refseq:XP_011540121.1|refseq:XP_016857366.1|ensembl:ENSG00000122417.16(gene)|ensembl:ENST00000317336.11(transcript)|ensembl:ENST00000359242.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0030030""(cell projection organization)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036064""(ciliary basal body)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR026099|mint:Q9ULJ1|panther:PTHR23162(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jNPx4rqCv9bEZelj7jbp42kW+NY632	rogid:wMO5dls+F2AsUWV+KzBmwjsvaY49606	intact-crc:3B8D2627733E4D0C|rigid:unh7/f9z2XcWKEfGRaYBfEPZRDo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULJ1	uniprotkb:Q9ZFR9	intact:EBI-715823|intact:EBI-2558792|uniprotkb:Q05C40|uniprotkb:Q5BJG5|uniprotkb:Q5TBX3|uniprotkb:Q5TBX4|uniprotkb:Q86X31|uniprotkb:A8MU56|uniprotkb:B4E037|ensembl:ENSP00000320165.8|ensembl:ENSP00000359600.2	intact:EBI-2840836|uniprotkb:Q0WDM2	psi-mi:odf2l_human(display_long)|uniprotkb:KIAA1229(gene name synonym)|uniprotkb:BCAP(gene name synonym)|uniprotkb:Basal body centriole-associated protein(gene name synonym)|uniprotkb:Outer dense fiber protein 2-like(gene name synonym)|uniprotkb:ODF2L(gene name)|psi-mi:ODF2L(display_short)	psi-mi:ure1_yerpe(display_long)|uniprotkb:ureC(gene name)|psi-mi:ureC(display_short)|uniprotkb:Urea amidohydrolase subunit alpha(gene name synonym)|uniprotkb:YPO2667(locus name)|uniprotkb:y1239(locus name)|uniprotkb:YP_2468(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862201|imex:IM-13779-6725	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005271111.1|refseq:NP_001007023.2|refseq:NP_001171694.1|refseq:NP_001171695.1|refseq:NP_065780.2|refseq:XP_011540121.1|refseq:XP_016857366.1|ensembl:ENSG00000122417.16(gene)|ensembl:ENST00000317336.11(transcript)|ensembl:ENST00000359242.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0030030""(cell projection organization)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036064""(ciliary basal body)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR026099|mint:Q9ULJ1|panther:PTHR23162(orthology-group)"	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011612(Urease alpha-subunit, N-terminal)|interpro:IPR005848(Urease, alpha subunit)|interpro:IPR017951|interpro:IPR017950|interpro:IPR029754|refseq:YP_002347616.1|go:""GO:0005737""(cytoplasm)|go:""GO:0009039""(urease activity)|go:""GO:0016151""(nickel cation binding)|go:""GO:0043419""(urea catabolic process)|refseq:WP_002212229.1|interpro:IPR032466|interpro:IPR050112|panther:PTHR43440(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wMO5dls+F2AsUWV+KzBmwjsvaY49606	rogid:AnzMzbsl9+3qLvUFVuG3yGKppAo632	intact-crc:E89E53E17D4355ED|rigid:TAW5gOlDMGX1JgVQEiWnDfGhBrI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BZF1	uniprotkb:Q7ARD3	intact:EBI-2684038|uniprotkb:Q52LQ3|uniprotkb:Q9P277|uniprotkb:Q8WXP8|uniprotkb:A8K1T2|uniprotkb:E9PE66|uniprotkb:E9PE68|uniprotkb:Q68D75|ensembl:ENSP00000261183.3	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:osbl8_human(display_long)|uniprotkb:OSBP10(gene name synonym)|uniprotkb:KIAA1451(gene name synonym)|uniprotkb:ORP8(gene name synonym)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862180|imex:IM-13779-6723	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001003712.1|refseq:NP_065892.1|refseq:XP_005268678.1|refseq:XP_006719287.1|refseq:NP_001306581.1|refseq:NP_001306584.1|dip:DIP-56130N|ensembl:ENSG00000091039.17(gene)|ensembl:ENST00000261183.8(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005548""(phospholipid transporter activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0010891""(negative regulation of triglyceride storage)|go:""GO:0015485""(cholesterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0016020""(membrane)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032541""(cortical endoplasmic reticulum)|go:""GO:0036150""(phosphatidylserine acyl-chain remodeling)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0046628""(positive regulation of insulin receptor signaling pathway)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070273""(phosphatidylinositol-4-phosphate binding)|go:""GO:0090204""(protein localization to nuclear pore)|go:""GO:0140343""(phosphatidylserine transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q9BZF1|rcsb pdb:1V88|rcsb pdb:5U77|rcsb pdb:5U78|rcsb pdb:8P7A|reactome:R-HSA-1482801|panther:PTHR10972(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KwZ5DFeGTIM3p/yP3XBNgr/v3O09606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:41B731E6907AD3C2|rigid:fE907u1Xm9JY5/SaAoZzQStO59M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARK4	uniprotkb:Q9ULJ1	intact:EBI-2849202|uniprotkb:Q74YZ8|uniprotkb:Q7ARG6|uniprotkb:Q7BT15|intact:EBI-2862232|uniprotkb:A0A3G5L2H4|uniprotkb:A0A1U8QNS3|uniprotkb:Q7CL24|uniprotkb:Q7CI35	intact:EBI-715823|intact:EBI-2558792|uniprotkb:Q05C40|uniprotkb:Q5BJG5|uniprotkb:Q5TBX3|uniprotkb:Q5TBX4|uniprotkb:Q86X31|uniprotkb:A8MU56|uniprotkb:B4E037|ensembl:ENSP00000320165.8|ensembl:ENSP00000359600.2	psi-mi:q7ark4_yerpe(display_long)|uniprotkb:ypmt1.57c(gene name)|psi-mi:ypmt1.57c(display_short)|uniprotkb:Y0016(gene name synonym)|uniprotkb:DNA replication protein DnaC(gene name synonym)|uniprotkb:YPO0030(locus name)|uniprotkb:YPO0096(locus name)|uniprotkb:YPO0172(locus name)|uniprotkb:YPO0248(locus name)|uniprotkb:YPO0385(locus name)|uniprotkb:YPO0527(locus name)|uniprotkb:YPO0566(locus name)|uniprotkb:YPO0638(locus name)|uniprotkb:YPO0779(locus name)|uniprotkb:YPO0825(locus name)|uniprotkb:YPO0923(locus name)|uniprotkb:YPO1014(locus name)|uniprotkb:YPO1085(locus name)|uniprotkb:YPO1131(locus name)|uniprotkb:YPO1339(locus name)|uniprotkb:YPO1426(locus name)|uniprotkb:YPO1519(locus name)|uniprotkb:YPO1622(locus name)|uniprotkb:YPO1691(locus name)|uniprotkb:YPO1730(locus name)|uniprotkb:YPO1751(locus name)|uniprotkb:YPO1901(locus name)|uniprotkb:YPO2025(locus name)|uniprotkb:YPO2086(locus name)|uniprotkb:YPO2177(locus name)|uniprotkb:YPO2364(locus name)|uniprotkb:YPO2397(locus name)|uniprotkb:YPO2517(locus name)|uniprotkb:YPO2642(locus name)|uniprotkb:YPO2722(locus name)|uniprotkb:YPO2809(locus name)|uniprotkb:YPO2931(locus name)|uniprotkb:YPO3208(locus name)|uniprotkb:YPO3252(locus name)|uniprotkb:YPO3283(locus name)|uniprotkb:YPO3435(locus name)|uniprotkb:YPO3543(locus name)|uniprotkb:YPO3592(locus name)|uniprotkb:YPO3700(locus name)|uniprotkb:YPO3755(locus name)|uniprotkb:YPO3773(locus name)|uniprotkb:YPO4009(locus name)|uniprotkb:YPPCP1.02(locus name)|uniprotkb:YPMT1.02(locus name)|uniprotkb:YPMT1.57c(locus name)	psi-mi:odf2l_human(display_long)|uniprotkb:KIAA1229(gene name synonym)|uniprotkb:BCAP(gene name synonym)|uniprotkb:Basal body centriole-associated protein(gene name synonym)|uniprotkb:Outer dense fiber protein 2-like(gene name synonym)|uniprotkb:ODF2L(gene name)|psi-mi:ODF2L(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862229|imex:IM-13779-6731	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001317493.1|refseq:NP_395228.1|refseq:NP_395337.2|refseq:NP_395401.1|refseq:NP_857912.1|refseq:YP_094026.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002611(IstB-like ATP-binding protein)|interpro:IPR028350|interpro:IPR027417|interpro:IPR047661|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006260""(DNA replication)|go:""GO:0006269""(DNA replication, synthesis of primer)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:1990077""(primosome complex)|refseq:YP_002345126.1|refseq:YP_002345187.1|refseq:YP_002345257.1|refseq:YP_002345329.1|refseq:YP_002345462.1|refseq:YP_002345600.1|refseq:YP_002345637.1|refseq:YP_002345705.1|refseq:YP_002345835.1|refseq:YP_002345879.1|refseq:YP_002345971.1|refseq:YP_002346057.1|refseq:YP_002346128.1|refseq:YP_002346173.1|refseq:YP_002346363.1|refseq:YP_002346449.1|refseq:YP_002346535.1|refseq:YP_002346633.1|refseq:YP_002346694.1|refseq:YP_002346731.1|refseq:YP_002346751.1|refseq:YP_002346891.1|refseq:YP_002347009.1|refseq:YP_002347067.1|refseq:YP_002347151.1|refseq:YP_002347331.1|refseq:YP_002347363.1|refseq:YP_002347481.1|refseq:YP_002347595.1|refseq:YP_002347669.1|refseq:YP_002347750.1|refseq:YP_002347861.1|refseq:YP_002348111.1|refseq:YP_002348153.1|refseq:YP_002348182.1|refseq:YP_002348327.1|refseq:YP_002348431.1|refseq:YP_002348477.1|refseq:YP_002348582.1|refseq:YP_002348635.1|refseq:YP_002348651.1|refseq:YP_002348876.1|panther:PTHR30050(orthology-group)"	"refseq:XP_005271111.1|refseq:NP_001007023.2|refseq:NP_001171694.1|refseq:NP_001171695.1|refseq:NP_065780.2|refseq:XP_011540121.1|refseq:XP_016857366.1|ensembl:ENSG00000122417.16(gene)|ensembl:ENST00000317336.11(transcript)|ensembl:ENST00000359242.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0030030""(cell projection organization)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036064""(ciliary basal body)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR026099|mint:Q9ULJ1|panther:PTHR23162(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yqskl8o49hYONtduM+rZmKno4uU632	rogid:wMO5dls+F2AsUWV+KzBmwjsvaY49606	intact-crc:46C3B8CED08CDCF2|rigid:vEs8NnHvTZIgVxomy6MJI6P9ciY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULJ1	uniprotkb:A0A2S9PGH0	intact:EBI-715823|intact:EBI-2558792|uniprotkb:Q05C40|uniprotkb:Q5BJG5|uniprotkb:Q5TBX3|uniprotkb:Q5TBX4|uniprotkb:Q86X31|uniprotkb:A8MU56|uniprotkb:B4E037|ensembl:ENSP00000320165.8|ensembl:ENSP00000359600.2	intact:EBI-2843672|uniprotkb:Q74VD9|uniprotkb:Q7CHN7|uniprotkb:A0A380SBG1|uniprotkb:Q0WGU1	psi-mi:odf2l_human(display_long)|uniprotkb:KIAA1229(gene name synonym)|uniprotkb:BCAP(gene name synonym)|uniprotkb:Basal body centriole-associated protein(gene name synonym)|uniprotkb:Outer dense fiber protein 2-like(gene name synonym)|uniprotkb:ODF2L(gene name)|psi-mi:ODF2L(display_short)	psi-mi:a0a2s9pgh0_yerpe(display_long)|uniprotkb:YPO1482(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862222|imex:IM-13779-6728	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005271111.1|refseq:NP_001007023.2|refseq:NP_001171694.1|refseq:NP_001171695.1|refseq:NP_065780.2|refseq:XP_011540121.1|refseq:XP_016857366.1|ensembl:ENSG00000122417.16(gene)|ensembl:ENST00000317336.11(transcript)|ensembl:ENST00000359242.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0030030""(cell projection organization)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036064""(ciliary basal body)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR026099|mint:Q9ULJ1|panther:PTHR23162(orthology-group)"	interpro:IPR010623(Protein of unknown function DUF1215)|interpro:IPR009612(ImcF-related)|refseq:WP_002211936.1|interpro:IPR048677|refseq:YP_002346497.1|interpro:IPR053156	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wMO5dls+F2AsUWV+KzBmwjsvaY49606	rogid:QiN5WQU27+ZNFJoP65QaVCbJABo632	intact-crc:C9F850CA23D59473|rigid:7xfq9mWDormjiYpgAtn3xp6PRy4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULJ1	uniprotkb:P58582	intact:EBI-715823|intact:EBI-2558792|uniprotkb:Q05C40|uniprotkb:Q5BJG5|uniprotkb:Q5TBX3|uniprotkb:Q5TBX4|uniprotkb:Q86X31|uniprotkb:A8MU56|uniprotkb:B4E037|ensembl:ENSP00000320165.8|ensembl:ENSP00000359600.2	intact:EBI-2846820|uniprotkb:Q0WIA6	psi-mi:odf2l_human(display_long)|uniprotkb:KIAA1229(gene name synonym)|uniprotkb:BCAP(gene name synonym)|uniprotkb:Basal body centriole-associated protein(gene name synonym)|uniprotkb:Outer dense fiber protein 2-like(gene name synonym)|uniprotkb:ODF2L(gene name)|psi-mi:ODF2L(display_short)	psi-mi:gshb_yerpe(display_long)|uniprotkb:gshB(gene name)|psi-mi:gshB(display_short)|uniprotkb:GSH synthetase(gene name synonym)|uniprotkb:Glutathione synthase(gene name synonym)|uniprotkb:YPO0935(locus name)|uniprotkb:y3321(locus name)|uniprotkb:YP_3507(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862240|imex:IM-13779-6729	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005271111.1|refseq:NP_001007023.2|refseq:NP_001171694.1|refseq:NP_001171695.1|refseq:NP_065780.2|refseq:XP_011540121.1|refseq:XP_016857366.1|ensembl:ENSG00000122417.16(gene)|ensembl:ENST00000317336.11(transcript)|ensembl:ENST00000359242.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0030030""(cell projection organization)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036064""(ciliary basal body)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR026099|mint:Q9ULJ1|panther:PTHR23162(orthology-group)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR006284(Glutathione synthetase, prokaryotic)|interpro:IPR004218(Prokaryotic glutathione synthetase, ATP-binding)|interpro:IPR004215(Prokaryotic glutathione synthetase, N-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|refseq:WP_002209976.1|go:""GO:0004363""(glutathione synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|refseq:YP_002345982.1|panther:PTHR21621(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wMO5dls+F2AsUWV+KzBmwjsvaY49606	rogid:2PCcRO+ezg1vmWad2fXePKESKh4632	intact-crc:4ADBCF0DEE25DC74|rigid:tE/9LZ1fnpUnpgwb9YYvNImsfgs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULJ1	uniprotkb:Q8CZY0	intact:EBI-715823|intact:EBI-2558792|uniprotkb:Q05C40|uniprotkb:Q5BJG5|uniprotkb:Q5TBX3|uniprotkb:Q5TBX4|uniprotkb:Q86X31|uniprotkb:A8MU56|uniprotkb:B4E037|ensembl:ENSP00000320165.8|ensembl:ENSP00000359600.2	intact:EBI-2843763	psi-mi:odf2l_human(display_long)|uniprotkb:KIAA1229(gene name synonym)|uniprotkb:BCAP(gene name synonym)|uniprotkb:Basal body centriole-associated protein(gene name synonym)|uniprotkb:Outer dense fiber protein 2-like(gene name synonym)|uniprotkb:ODF2L(gene name)|psi-mi:ODF2L(display_short)	psi-mi:q8czy0_yerpe(display_long)|uniprotkb:y3182(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862215|imex:IM-13779-6732	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005271111.1|refseq:NP_001007023.2|refseq:NP_001171694.1|refseq:NP_001171695.1|refseq:NP_065780.2|refseq:XP_011540121.1|refseq:XP_016857366.1|ensembl:ENSG00000122417.16(gene)|ensembl:ENST00000317336.11(transcript)|ensembl:ENST00000359242.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0030030""(cell projection organization)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036064""(ciliary basal body)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR026099|mint:Q9ULJ1|panther:PTHR23162(orthology-group)"	"interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR041954|interpro:IPR050612"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wMO5dls+F2AsUWV+KzBmwjsvaY49606	rogid:Y5d3heMPjpe23bUutQ9OKW+v73g632	intact-crc:C2EB3ED50EFA55F9|rigid:jjIOm/hVJztxnFDQtCnJGVrxXy4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULJ1	uniprotkb:Q8ZBK0	intact:EBI-715823|intact:EBI-2558792|uniprotkb:Q05C40|uniprotkb:Q5BJG5|uniprotkb:Q5TBX3|uniprotkb:Q5TBX4|uniprotkb:Q86X31|uniprotkb:A8MU56|uniprotkb:B4E037|ensembl:ENSP00000320165.8|ensembl:ENSP00000359600.2	intact:EBI-2862250|uniprotkb:Q0WBN7	psi-mi:odf2l_human(display_long)|uniprotkb:KIAA1229(gene name synonym)|uniprotkb:BCAP(gene name synonym)|uniprotkb:Basal body centriole-associated protein(gene name synonym)|uniprotkb:Outer dense fiber protein 2-like(gene name synonym)|uniprotkb:ODF2L(gene name)|psi-mi:ODF2L(display_short)	psi-mi:cueo_yerpe(display_long)|uniprotkb:cueO(gene name)|psi-mi:cueO(display_short)|uniprotkb:Copper efflux oxidase(gene name synonym)|uniprotkb:Cuprous oxidase(gene name synonym)|uniprotkb:YPO3409(locus name)|uniprotkb:YP_0276(locus name)|uniprotkb:y0777(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862247|imex:IM-13779-6730	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005271111.1|refseq:NP_001007023.2|refseq:NP_001171694.1|refseq:NP_001171695.1|refseq:NP_065780.2|refseq:XP_011540121.1|refseq:XP_016857366.1|ensembl:ENSG00000122417.16(gene)|ensembl:ENST00000317336.11(transcript)|ensembl:ENST00000359242.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0030030""(cell projection organization)|go:""GO:0034451""(centriolar satellite)|go:""GO:0036064""(ciliary basal body)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR026099|mint:Q9ULJ1|panther:PTHR23162(orthology-group)"	"interpro:IPR019546|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR002355(Multicopper oxidase, copper-binding site)|interpro:IPR008972(Cupredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|refseq:WP_002209340.1|go:""GO:0004322""(ferroxidase activity)|go:""GO:0005507""(copper ion binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002348301.1|interpro:IPR045087|panther:PTHR11709(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wMO5dls+F2AsUWV+KzBmwjsvaY49606	rogid:b2wVZLVoAzwGS9U4iPLOm44PTeA632	intact-crc:D37E473C0EFF24DF|rigid:0uyHKVx/9D7T2O43hq+ycfsWbqc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75703	uniprotkb:A0A2U2GX99	intact:EBI-2862273	intact:EBI-2854330|uniprotkb:Q0WIX6|uniprotkb:Q7CGJ4|uniprotkb:A0A384L6K3	psi-mi:o75703_human(display_long)|uniprotkb:A-270G1.2(gene name)|psi-mi:A-270G1.2(display_short)	psi-mi:a0a2u2gx99_yerpe(display_long)|uniprotkb:YPO0698(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862277|imex:IM-13779-6734	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007991(RNA polymerase I specific transcription initiation factor RRN3)|go:""GO:0001181""(RNA polymerase I general transcription initiation factor activity)|go:""GO:0006360""(transcription by RNA polymerase I)|go:""GO:0006361""(transcription initiation at RNA polymerase I promoter)"	"interpro:IPR042186|interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR025885|interpro:IPR025949|refseq:WP_002211458.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR037224|interpro:IPR043142|refseq:YP_002345762.1|panther:PTHR30451(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:p3myzXdwgK/KfPh2G0dxQ2uxHlk9606	rogid:JVraEv1dK3EeqcZNuRxbt8xrN34632	intact-crc:9B9260F34098E7DF|rigid:8KoFZu+H2eZCf4L1p+s9eZ4qJk4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60290	uniprotkb:A0A2U2H160	intact:EBI-310635|uniprotkb:A0AUL8|ensembl:ENSP00000223210.4|intact:EBI-28977689	intact:EBI-2839804|uniprotkb:Q74VL9|uniprotkb:Q0WHA0|uniprotkb:Q7CHF5|uniprotkb:A0A384KFZ8|uniprotkb:A0A5P8YDY1	psi-mi:zn862_human(display_long)|uniprotkb:ZNF862(gene name)|psi-mi:ZNF862(display_short)|uniprotkb:KIAA0543(gene name synonym)	psi-mi:a0a2u2h160_yerpe(display_long)|uniprotkb:YPO1313(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862296|imex:IM-13779-6737	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001092690.1|ensembl:ENSG00000106479.11(gene)|ensembl:ENST00000223210.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046983""(protein dimerization activity)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR006580(Zinc finger, TTF-type)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036051|panther:PTHR46880(orthology-group)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|refseq:WP_002208782.1|interpro:IPR010916(TonB box, conserved site)|go:""GO:0009279""(cell outer membrane)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002346338.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vKwM9UMMfHlSBIwW2TTFHNh00Ds9606	rogid:Mg0owqCn0ozvLrRu4vW8Rgc4sZk632	intact-crc:64DED2201B3CA047|rigid:cmWIC26W9HZvwCe5tGqqlQhRRMs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94875	uniprotkb:A0A5P8YH58	intact:EBI-311323|intact:EBI-747334|uniprotkb:B7Z1G5|uniprotkb:C9JKV9|uniprotkb:G3XAI0|intact:EBI-2804177|uniprotkb:A6NEK9|uniprotkb:O60592|uniprotkb:O60593|uniprotkb:Q96EX0|uniprotkb:D3DP62|uniprotkb:D3DP63|intact:EBI-28977791|uniprotkb:B7Z3X6|ensembl:ENSP00000284776.7|uniprotkb:E9PAS5|uniprotkb:E9PAW4|uniprotkb:B3KPQ7|uniprotkb:H7BXR4|uniprotkb:J3KNZ5|intact:EBI-10983198|intact:EBI-10965282	intact:EBI-2862284|uniprotkb:Q74TH7|uniprotkb:Q7CIS8|uniprotkb:Q0WEC9	psi-mi:srbs2_human(display_long)|uniprotkb:SORBS2(gene name)|psi-mi:SORBS2(display_short)|uniprotkb:ARGBP2(gene name synonym)|uniprotkb:KIAA0777(gene name synonym)|uniprotkb:Arg/Abl-interacting protein 2(gene name synonym)|uniprotkb:Sorbin(gene name synonym)|uniprotkb:Arg-binding protein 2(gene name synonym)	psi-mi:a0a5p8yh58_yerpe(display_long)|uniprotkb:pykF(gene name)|psi-mi:pykF(display_short)|uniprotkb:YPO2393(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862289|imex:IM-13779-6735	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001139142.1|refseq:NP_001139144.1|refseq:NP_001139145.1|refseq:NP_066547.1|refseq:NP_001139146.1|ensembl:ENSG00000154556.20(gene)|ensembl:ENST00000284776.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030018""(Z disc)|go:""GO:0030027""(lamellipodium)|go:""GO:0030425""(dendrite)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045202""(synapse)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061049""(cell growth involved in cardiac muscle cell development)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036028|interpro:IPR050384|mint:O94875|rcsb pdb:5VEI|refseq:NP_001139143.1|refseq:NP_001257700.1|refseq:NP_003594.3|refseq:XP_005263369.1|refseq:XP_006714453.1|refseq:XP_016864260.1|dip:DIP-31634N|panther:PTHR14167(orthology-group)"	"interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR018209|interpro:IPR040442|refseq:WP_002210936.1|interpro:IPR015806(Pyruvate kinase, beta-barrel)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006096""(glycolytic process)|go:""GO:0016301""(kinase activity)|go:""GO:0030955""(potassium ion binding)|interpro:IPR036918|refseq:YP_002347359.1|panther:PTHR11817(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ficlNf23am8NpwQVRUKXeVUJTsQ9606	rogid:sVCLw1i83HZRITJVdGJzfdlDWSk632	intact-crc:D65F79790A15BF1D|rigid:Et7F5yAkvtrnPejDM/TdyLSLfyY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YLE8	uniprotkb:O95273	intact:EBI-2841627|uniprotkb:Q74Y48|uniprotkb:A0A384L7I3|uniprotkb:A0A0H2W0Y8|uniprotkb:Q7CFX4	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213.4	psi-mi:a0a5p8yle8_yerpe(display_long)|uniprotkb:malQ(gene name)|psi-mi:malQ(display_short)|uniprotkb:Amylomaltase(gene name synonym)|uniprotkb:Disproportionating enzyme(gene name synonym)|uniprotkb:YPO0126(locus name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862259|imex:IM-13779-6733	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003385(Glycoside hydrolase, family 77)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR048458|go:""GO:0004134""(4-alpha-glucanotransferase activity)|go:""GO:0005975""(carbohydrate metabolic process)|refseq:YP_002345212.1|refseq:WP_002208925.1|panther:PTHR32438(orthology-group)"	"refseq:NP_036274.3|ensembl:ENSG00000166946.14(gene)|ensembl:ENST00000300213.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0016604""(nuclear body)|interpro:IPR026907|interpro:IPR049317|interpro:IPR049318|mint:O95273|rcsb pdb:3AY5|panther:PTHR15492(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JdI4fLE1gbtuqHycNtXRKKfEZ7Y632	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:A38AB377A8D5ABAE|rigid:+Qr87Ur2pAkcX3B9PZNf8YJktL0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YFD8	uniprotkb:O75807	intact:EBI-2844797|uniprotkb:Q74TW8|uniprotkb:A0A0H2W658|uniprotkb:Q7CIM3|uniprotkb:A0A384L807	intact:EBI-714746|uniprotkb:Q6IA96|uniprotkb:Q9NVU6|intact:EBI-28977765|ensembl:ENSP00000200453.4|uniprotkb:B4DKQ3	psi-mi:a0a5p8yfd8_yerpe(display_long)|uniprotkb:trpE(gene name)|psi-mi:trpE(display_short)|uniprotkb:YPO2208(locus name)	psi-mi:pr15a_human(display_long)|uniprotkb:Myeloid differentiation primary response protein MyD116 homolog(gene name synonym)|uniprotkb:PPP1R15A(gene name)|psi-mi:PPP1R15A(display_short)|uniprotkb:GADD34(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD34(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862266|imex:IM-13779-6736	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR019999|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR005257(Anthranilate synthase component I, TrpE)|interpro:IPR015890(Chorismate binding, C-terminal)|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004049""(anthranilate synthase activity)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347179.1|panther:PTHR11236(orthology-group)"	"refseq:NP_055145.3|ensembl:ENSG00000087074.9(gene)|ensembl:ENST00000200453.6(transcript)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0006915""(apoptotic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0016020""(membrane)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0032058""(positive regulation of translational initiation in response to stress)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0043558""(regulation of translational initiation in response to stress)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|interpro:IPR019523|interpro:IPR051254|mint:O75807|rcsb pdb:4XPN|rcsb pdb:7NXV|rcsb pdb:7NZM|rcsb pdb:8QZZ|reactome:R-HSA-2173788|reactome:R-HSA-9648895|panther:PTHR16489(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4yY3KOTpkixAVvXxxbToZJUfRYM632	rogid:2pmlIgM2OX5qK5Bvb1p9x9ZERLw9606	intact-crc:35F5EED1555438B6|rigid:UDLbxHJ2BicZOt35yTg7zZ8wktc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P52948	uniprotkb:Q8ZIC6	intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091.5	intact:EBI-2860508|uniprotkb:Q8CZR0|uniprotkb:Q0WJ87	psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym)	psi-mi:uxac_yerpe(display_long)|uniprotkb:uxaC(gene name)|psi-mi:uxaC(display_short)|uniprotkb:Glucuronate isomerase(gene name synonym)|uniprotkb:Uronic isomerase(gene name synonym)|uniprotkb:YPO0579(locus name)|uniprotkb:y3600(locus name)|uniprotkb:YP_2899(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862339|imex:IM-13779-6739	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENSG00000110713.18(gene)|ensembl:ENST00000359171.8(transcript)|go:""GO:0000973""(post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006508""(proteolysis)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006999""(nuclear pore organization)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0016604""(nuclear body)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0031080""(nuclear pore outer ring)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034398""(telomere tethering at nuclear periphery)|go:""GO:0034399""(nuclear periphery)|go:""GO:0042405""(nuclear inclusion body)|go:""GO:0044614""(nuclear pore cytoplasmic filaments)|go:""GO:0044615""(nuclear pore nuclear basket)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0051028""(mRNA transport)|go:""GO:0051292""(nuclear pore complex assembly)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|rcsb pdb:7F60|rcsb pdb:7F90|rcsb pdb:7MNI|rcsb pdb:7PEQ|rcsb pdb:7Q64|rcsb pdb:7Q65|rcsb pdb:7Q66|rcsb pdb:7Q67|rcsb pdb:7VPG|rcsb pdb:7VPH|rcsb pdb:8CI8|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-9705671|dip:DIP-32484N|panther:PTHR23198(orthology-group)"	"interpro:IPR003766(Glucuronate isomerase)|refseq:WP_002210410.1|interpro:IPR032466|go:""GO:0008880""(glucuronate isomerase activity)|go:""GO:0019698""(D-galacturonate catabolic process)|go:""GO:0042840""(D-glucuronate catabolic process)|refseq:YP_002345651.1|panther:PTHR30068(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606	rogid:xvb/gj4dlbyJ5YEc5bnU6UL77to632	intact-crc:CC878B43DFE6EC3F|rigid:u2WrWd8p+eMF7hx8YbSpl4TESIg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00376	uniprotkb:A0A0H2W225	intact:EBI-2811724	intact:EBI-2844774	psi-mi:o00376_human(display_long)	psi-mi:a0a0h2w225_yerpe(display_long)|uniprotkb:sbcC2(gene name)|psi-mi:sbcC2(display_short)|uniprotkb:sbcC(gene name synonym)|uniprotkb:YP_0725(locus name)|uniprotkb:y0976(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862320|imex:IM-13779-6738	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR042566|interpro:IPR004244(Transposase, L1)|go:""GO:0004803""(transposase activity)|interpro:IPR035300|interpro:IPR035301|interpro:IPR043636"	"interpro:IPR027417|interpro:IPR038729|uniprotkb:A0A6B3T1W4(uniprot-removed-ac)|go:""GO:0004527""(exonuclease activity)|go:""GO:0006302""(double-strand break repair)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002223265.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VAmTDezlE5ojKqzukuXq3RiDIiM9606	rogid:kLIIS2zCAycudIvZsl7pSdsTqz0632	intact-crc:FBC0E329F5C1C6BE|rigid:nvFCRADGIAlaXBFUnfArgJlmh/Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PBF6	uniprotkb:Q5VZ03	intact:EBI-2858208|uniprotkb:Q74RW5|uniprotkb:Q7CGC7|uniprotkb:A0A3N4BUB9|uniprotkb:Q0WJ85	intact:EBI-2862327|uniprotkb:Q8TBG6|uniprotkb:B1AMD0|ensembl:ENSP00000365014.3|ensembl:ENSP00000508470.1|ensembl:ENSP00000516996.1|ensembl:ENSP00000516997.1	psi-mi:a0a2s9pbf6_yerpe(display_long)|uniprotkb:uxaA(gene name)|psi-mi:uxaA(display_short)|uniprotkb:YPO0581(locus name)	psi-mi:nxnl2_human(display_long)|uniprotkb:NXNL2(gene name)|psi-mi:NXNL2(display_short)|uniprotkb:C9orf121(gene name synonym)|uniprotkb:Rod-derived cone viability factor 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862332|imex:IM-13779-6741	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007392(D-galactarate dehydratase/Altronate hydrolase, C-terminal)|interpro:IPR013974(SAF domain)|interpro:IPR044144|interpro:IPR052172|refseq:WP_002210408.1|go:""GO:0016787""(hydrolase activity)|go:""GO:0016829""(lyase activity)|interpro:IPR048332|refseq:YP_002345653.1"	"refseq:NP_001155097.1|refseq:NP_660326.2|ensembl:ENSG00000130045.17(gene)|ensembl:ENSG00000291520.1(gene)|ensembl:ENST00000375854.8(transcript)|ensembl:ENST00000649870.2(transcript)|ensembl:ENST00000707837.1(transcript)|ensembl:ENST00000707838.1(transcript)|go:""GO:0007601""(visual perception)|go:""GO:0007608""(sensory perception of smell)|go:""GO:0045494""(photoreceptor cell maintenance)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR029519|interpro:IPR036249|panther:PTHR46762(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HPdHp8PXEzf8Z8gFJJj/FAsINEk632	rogid:7/bnZlH77tAPAKvLPNgxRnm/koU9606	intact-crc:B440E63D3EF47D5A|rigid:L/F8SmtBegVZBndA6oQQjRBmFCI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA76	uniprotkb:Q6ZNJ1	intact:EBI-2846943|uniprotkb:Q0WA76	intact:EBI-2862306|uniprotkb:Q6UX91|uniprotkb:Q8NAC9|uniprotkb:Q6P994|uniprotkb:O60288|ensembl:ENSP00000415034.2	psi-mi:glgx_yerpe(display_long)|uniprotkb:glgX(gene name)|psi-mi:glgX(display_short)|uniprotkb:Limit dextrin alpha-1,6-maltotetraose-hydrolase(gene name synonym)|uniprotkb:YPO3941(locus name)|uniprotkb:YP_3303(locus name)|uniprotkb:y3887(locus name)	psi-mi:nbel2_human(display_long)|uniprotkb:NBEAL2(gene name)|psi-mi:NBEAL2(display_short)|uniprotkb:KIAA0540(gene name synonym)|uniprotkb:UNQ253/PRO290(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862303|imex:IM-13779-6742	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR022844|interpro:IPR011837(Glycogen debranching enzyme GlgX)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR040784|go:""GO:0004133""(obsolete glycogen debranching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005980""(glycogen catabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_002209499.1|interpro:IPR044505|refseq:YP_002348812.1|panther:PTHR43002(orthology-group)"	"efo:""Orphanet:721""|ensembl:ENSG00000160796.18(gene)|ensembl:ENST00000450053.8(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030220""(platelet formation)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|interpro:IPR046851|interpro:IPR046852|interpro:IPR050865|reactome:R-HSA-6798695|refseq:NP_055990.1|refseq:XP_011531835.1|panther:PTHR13743(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8sHtj0obGqvrIdGE1JWk8okcbRM632	rogid:H5iNI+TNWHLPeyFllmtH7p2s/uE9606	intact-crc:FE342B3DAD1F1A3B|rigid:JJx9qnsAPzkoOhcLnQ9dqbKLsS4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKK9	uniprotkb:A0A5P8YKW4	intact:EBI-721623|uniprotkb:Q6IAG0|uniprotkb:Q9UH49|uniprotkb:A8K516|ensembl:ENSP00000419628.1	intact:EBI-2850165	psi-mi:nudt5_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 5(gene name synonym)|uniprotkb:YSA1H(gene name synonym)|uniprotkb:NUDT5(gene name)|psi-mi:NUDT5(display_short)|uniprotkb:HSPC115(orf name)|uniprotkb:8-oxo-dGDP phosphatase(gene name synonym)|uniprotkb:NUDIX5(gene name synonym)|uniprotkb:Nuclear ATP-synthesis protein NUDIX5(gene name synonym)	psi-mi:a0a5p8ykw4_yerpe(display_long)|uniprotkb:YP_3671(locus name)|uniprotkb:y3665(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862346|imex:IM-13779-6740	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_054861.2|ensembl:ENSG00000165609.14(gene)|ensembl:ENST00000491614.6(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006753""(nucleoside phosphate metabolic process)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0009191""(ribonucleoside diphosphate catabolic process)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0019144""(ADP-sugar diphosphatase activity)|go:""GO:0019303""(D-ribose catabolic process)|go:""GO:0019693""(ribose phosphate metabolic process)|go:""GO:0030515""(snoRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044715""(8-oxo-dGDP phosphatase activity)|go:""GO:0044716""(8-oxo-GDP phosphatase activity)|go:""GO:0047631""(ADP-ribose diphosphatase activity)|go:""GO:0055086""(nucleobase-containing small molecule metabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990966""(ATP generation from poly-ADP-D-ribose)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|mint:Q9UKK9|rcsb pdb:2DSB|rcsb pdb:2DSC|rcsb pdb:2DSD|rcsb pdb:3AC9|rcsb pdb:3ACA|rcsb pdb:3BM4|rcsb pdb:3L85|rcsb pdb:5NQR|rcsb pdb:5NWH|rcsb pdb:5QJ4|rcsb pdb:5QJ5|rcsb pdb:5QJ6|rcsb pdb:5QJ7|rcsb pdb:5QJ8|rcsb pdb:5QJ9|rcsb pdb:5QJA|rcsb pdb:5QJB|rcsb pdb:5QJC|rcsb pdb:5QJD|rcsb pdb:5QJE|rcsb pdb:5QJF|rcsb pdb:5QJG|rcsb pdb:5QJH|rcsb pdb:5QJI|rcsb pdb:5QJJ|rcsb pdb:5QJK|rcsb pdb:5QJL|rcsb pdb:5QJM|rcsb pdb:5QJN|rcsb pdb:5QJO|rcsb pdb:5QJP|rcsb pdb:5QJQ|rcsb pdb:5QJR|rcsb pdb:5QJS|rcsb pdb:5QJT|rcsb pdb:5QJU|rcsb pdb:5QJV|rcsb pdb:5QJW|rcsb pdb:5QJX|rcsb pdb:5QJY|rcsb pdb:5QJZ|rcsb pdb:5QK0|rcsb pdb:5QK1|rcsb pdb:5QK2|rcsb pdb:5QK3|rcsb pdb:5QK4|rcsb pdb:5QK5|rcsb pdb:5QK6|rcsb pdb:5QK7|rcsb pdb:5QK8|rcsb pdb:5QK9|rcsb pdb:5QKA|rcsb pdb:5QKB|rcsb pdb:5QTL|rcsb pdb:5QTM|rcsb pdb:5QTN|rcsb pdb:5QTO|rcsb pdb:5QTP|rcsb pdb:5QTQ|rcsb pdb:5QTR|rcsb pdb:5QTS|rcsb pdb:6GRU|rcsb pdb:8PTT|rcsb pdb:8RDZ|rcsb pdb:8RIY|reactome:R-HSA-2393930|panther:PTHR11839(orthology-group)"	interpro:IPR001646(Pentapeptide repeat)|interpro:IPR018683|refseq:WP_002224087.1|uniprotkb:A0A6B3T2Z3(uniprot-removed-ac)|interpro:IPR052949	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jeBjAoLC9hGn34DKTP5QehZeZwM9606	rogid:3NJSaWlDR7yCRld+Bz8Son5hdFQ632	intact-crc:0234EBD5134CAA66|rigid:Hwe4STBOGi4IdZNsAFbBJOk+2TA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19338	uniprotkb:A0A454XXH7	intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195.4	intact:EBI-2851240|uniprotkb:Q74Y15|uniprotkb:A0A0H2W158|uniprotkb:Q7CFV5|uniprotkb:A0A384K924	psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym)	psi-mi:a0a454xxh7_yerpe(display_long)|uniprotkb:YPO0168(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862381|imex:IM-13779-6747	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005372.2|dip:DIP-89N|panther:PTHR48034(orthology-group)|ensembl:ENSG00000115053.17(gene)|ensembl:ENST00000322723.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0042731""(PH domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0044547""(DNA topoisomerase binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0160056""(macropinosome membrane)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226|reactome:R-HSA-9820960"	interpro:IPR027417|refseq:WP_002215686.1|interpro:IPR033186|refseq:YP_002345254.1|interpro:IPR051162|panther:PTHR30121(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606	rogid:7T8Io5VjMpoAGWF393x9GYtAK2w632	intact-crc:D2E6125B85C161A0|rigid:K8BBjexWPre03sZEik4qYoFzMZI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19338	uniprotkb:A0A3N4BEU0	intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195.4	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym)	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862374|imex:IM-13779-6745	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005372.2|dip:DIP-89N|panther:PTHR48034(orthology-group)|ensembl:ENSG00000115053.17(gene)|ensembl:ENST00000322723.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0042731""(PH domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0044547""(DNA topoisomerase binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0160056""(macropinosome membrane)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226|reactome:R-HSA-9820960"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	intact-crc:2112828107AFB471|rigid:u4vAsTAhARvC0YM/vdLxUY0os1g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0R8	uniprotkb:P19338	intact:EBI-2842494	intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195.4	psi-mi:q8d0r8_yerpe(display_long)|uniprotkb:y1697(locus name)	psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862360|imex:IM-13779-6746	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010069(Adhesin HecA 20-residue repeat x2)|interpro:IPR006914(Protein of unknown function DUF638, haemagglutinin/haemolysin putative)|interpro:IPR008619(Filamentous haemagglutinin, bacterial)|interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR025157|interpro:IPR024973|go:""GO:0003824""(catalytic activity)|go:""GO:0090729""(toxin activity)"	"refseq:NP_005372.2|dip:DIP-89N|panther:PTHR48034(orthology-group)|ensembl:ENSG00000115053.17(gene)|ensembl:ENST00000322723.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0042731""(PH domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0044547""(DNA topoisomerase binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0160056""(macropinosome membrane)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226|reactome:R-HSA-9820960"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:9COFgNsEzFFJW9Occ82iuwwcF+Y632	rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606	intact-crc:3DDC468DE956E150|rigid:6JErkWfev6ZpnYLcd6wbO47yLZA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZQ9	uniprotkb:P19338	intact:EBI-2852846|uniprotkb:Q74RW8	intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195.4	psi-mi:q8czq9_yerpe(display_long)|uniprotkb:y3602(locus name)|uniprotkb:exuR(gene name)|psi-mi:exuR(display_short)|uniprotkb:YP_2896(locus name)	psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862367|imex:IM-13779-6744	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011711(GntR, C-terminal)|interpro:IPR000524(Bacterial regulatory protein GntR, HTH)|interpro:IPR008920(Fatty acid responsive transcription factor FadR, C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390"	"refseq:NP_005372.2|dip:DIP-89N|panther:PTHR48034(orthology-group)|ensembl:ENSG00000115053.17(gene)|ensembl:ENST00000322723.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0042731""(PH domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0044547""(DNA topoisomerase binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0160056""(macropinosome membrane)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226|reactome:R-HSA-9820960"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:RD2sxgq5tm9YnJVsIx4EdMD3/Uw632	rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606	intact-crc:CD707EDAE90AEE48|rigid:8Phyf8JlMfpapAfhDYl5X1bXl0w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CK09	uniprotkb:Q8NFP7	intact:EBI-2851418|uniprotkb:Q7B0V6|uniprotkb:Q74WP0|uniprotkb:Q0WCG5|uniprotkb:A0A5P8YIG7	intact:EBI-726826|ensembl:ENSP00000348831.2|ensembl:ENSP00000365174.3|uniprotkb:Q86VK1|uniprotkb:Q86VR0|uniprotkb:A8K7D7|uniprotkb:D3DX69	psi-mi:q7ck09_yerpe(display_long)|uniprotkb:ddhA(gene name)|psi-mi:ddhA(display_short)|uniprotkb:YPO3115(locus name)|uniprotkb:rfbF(gene name synonym)	"psi-mi:nud10_human(display_long)|uniprotkb:Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 10(gene name synonym)|uniprotkb:NUDT10(gene name)|psi-mi:NUDT10(display_short)|uniprotkb:APS2(gene name synonym)|uniprotkb:DIPP3A(gene name synonym)|uniprotkb:hAps2(gene name synonym)|uniprotkb:""Diadenosine hexaphosphate hydrolase (AMP-forming)""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862353|imex:IM-13779-6743	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029044|interpro:IPR013446(Glucose-1-phosphate cytidylyltransferase)|interpro:IPR005835(Nucleotidyl transferase)|go:""GO:0009243""(O antigen biosynthetic process)|go:""GO:0047343""(glucose-1-phosphate cytidylyltransferase activity)|refseq:YP_002348023.1|interpro:IPR046981|panther:PTHR47183(orthology-group)"	"go:""GO:0005829""(cytosol)|ensembl:ENSG00000122824.11(gene)|ensembl:ENST00000356450.3(transcript)|ensembl:ENST00000376006.7(transcript)|go:""GO:0000298""(endopolyphosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0008486""(diphosphoinositol-polyphosphate diphosphatase activity)|go:""GO:0034431""(""bis(5'-adenosyl)-hexaphosphatase activity"")|go:""GO:0034432""(""bis(5'-adenosyl)-pentaphosphatase activity"")|go:""GO:0046872""(metal ion binding)|go:""GO:0071543""(diphosphoinositol polyphosphate metabolic process)|go:""GO:1901907""(diadenosine pentaphosphate catabolic process)|go:""GO:1901909""(diadenosine hexaphosphate catabolic process)|go:""GO:1901911""(""adenosine 5'-(hexahydrogen pentaphosphate) catabolic process"")|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR047198|rcsb pdb:3MCF|reactome:R-HSA-1855167|refseq:NP_694853.1|refseq:NP_001291892.1|panther:PTHR12629(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TBBjggvwoVzR1lBlAwLFQUWZ5nk632	rogid:9jaz04OM+Dab/eP068W7mVFT8ds9606	intact-crc:7F65611B57C507F9|rigid:oeQzjDZjutjwTC3x8tGZDUvy/cs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75694	uniprotkb:A0A2U2H2G3	intact:EBI-1050769|uniprotkb:Q9UBE9|uniprotkb:Q9UFL5|intact:EBI-28983292|ensembl:ENSP00000231498.3	intact:EBI-2862405|uniprotkb:Q74PP9|uniprotkb:A0A0H2W9X2|uniprotkb:Q7CL82|uniprotkb:A0A384KHV9	psi-mi:nu155_human(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0791(gene name synonym)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short)	psi-mi:a0a2u2h2g3_yerpe(display_long)|uniprotkb:treR(gene name)|psi-mi:treR(display_short)|uniprotkb:YPO3698(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862410|imex:IM-13779-6751	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000113569.17(gene)|ensembl:ENST00000231498.8(transcript)|go:""GO:0000972""(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0016020""(membrane)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035196""(miRNA processing)|go:""GO:0036228""(protein localization to nuclear inner membrane)|go:""GO:0044611""(nuclear pore inner ring)|go:""GO:0086014""(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|interpro:IPR042538|mint:O75694|rcsb pdb:5A9Q|rcsb pdb:5IJN|rcsb pdb:5IJO|rcsb pdb:7EYE|rcsb pdb:7EYF|rcsb pdb:7EYQ|rcsb pdb:7PER|rcsb pdb:7R1Y|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9705671|refseq:NP_004289.1|refseq:NP_705618.1|efo:""Orphanet:334""|panther:PTHR10350(orthology-group)"	"interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR012771(Trehalose operon repressor)|interpro:IPR000843(Bacterial regulatory protein, LacI)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR001761(Periplasmic binding protein/LacI transcriptional regulator)|interpro:IPR028082|refseq:WP_002210106.1|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005991""(trehalose metabolic process)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002348580.1|panther:PTHR30146(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:k6LjWvJdqtT78G4Wu12rJX/2WHo9606	rogid:MNhorU1MO5N0WNKjY028y5gIvvY632	intact-crc:6832D6A04E27A514|rigid:21W48CwCIyIjkmE1uwXpSSYGUw4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96KG9	uniprotkb:Q7ARD3	intact:EBI-949287|intact:EBI-28972634|uniprotkb:A6NJF1|uniprotkb:Q96G50|uniprotkb:Q96KG8|uniprotkb:Q96KH1|uniprotkb:Q9HAW5|uniprotkb:Q9HBL3|uniprotkb:Q9NR53|ensembl:ENSP00000270176.5	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:scyl1_human(display_long)|uniprotkb:SCY1-like protein 1(gene name synonym)|uniprotkb:Teratoma-associated tyrosine kinase(gene name synonym)|uniprotkb:Telomerase transcriptional element-interacting factor(gene name synonym)|uniprotkb:Telomerase regulation-associated protein(gene name synonym)|uniprotkb:SCYL1(gene name)|psi-mi:SCYL1(display_short)|uniprotkb:Coated vesicle-associated kinase of 90 kDa(gene name synonym)|uniprotkb:CVAK90(gene name synonym)|uniprotkb:GKLP(gene name synonym)|uniprotkb:NTKL(gene name synonym)|uniprotkb:TAPK(gene name synonym)|uniprotkb:TEIF(gene name synonym)|uniprotkb:TRAP(gene name synonym)|uniprotkb:HT019(orf name)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862417|imex:IM-13779-6749	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:466794""|ensembl:ENSG00000142186.18(gene)|ensembl:ENST00000270176.10(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0006954""(inflammatory response)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0021522""(spinal cord motor neuron differentiation)|go:""GO:0030126""(COPI vesicle coat)|go:""GO:0045296""(cadherin binding)|go:""GO:0048666""(neuron development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR051177|mint:Q96KG9|refseq:NP_001041683.1|refseq:NP_065731.3|refseq:XP_005274177.1|panther:PTHR12984(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qHL7to7M3sjqepd3yuU1uo4Mhy49606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:696E10FC96B281CF|rigid:Pbc75+8LFYqiWNJP6TWnkBCI8Y0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1L8	uniprotkb:P35658	intact:EBI-2862395	intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400.5	psi-mi:q8d1l8_yerpe(display_long)|uniprotkb:y0306(locus name)	psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862398|imex:IM-13779-6748	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR036388|interpro:IPR009057(Homeodomain-like)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR052057|go:""GO:0043565""(sequence-specific DNA binding)|interpro:IPR055247"	"efo:""Orphanet:402014""|efo:""Orphanet:99861""|ensembl:ENSG00000126883.19(gene)|ensembl:ENST00000359428.10(transcript)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0017056""(structural constituent of nuclear pore)|go:""GO:0046822""(regulation of nucleocytoplasmic transport)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:1990876""(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC|rcsb pdb:3FMO|rcsb pdb:3FMP|rcsb pdb:5DIS|rcsb pdb:7R5J|rcsb pdb:7R5K|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9705671|refseq:NP_001305253.1|refseq:NP_001305254.1|refseq:NP_005076.3|dip:DIP-38367N|panther:PTHR23193(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RKQK6Ior4Jj6IPnayJn8mxLLPK8632	rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606	intact-crc:F29B548911C74E44|rigid:vy59Ryi+VK1PHfoBmBpl/7g2p+s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9X6B0	uniprotkb:Q96KG9	intact:EBI-2844324|intact:EBI-2856296|uniprotkb:Q0WBX3	intact:EBI-949287|intact:EBI-28972634|uniprotkb:A6NJF1|uniprotkb:Q96G50|uniprotkb:Q96KG8|uniprotkb:Q96KH1|uniprotkb:Q9HAW5|uniprotkb:Q9HBL3|uniprotkb:Q9NR53|ensembl:ENSP00000270176.5	psi-mi:katg_yerpe(display_long)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)|uniprotkb:katY(gene name synonym)|uniprotkb:Antigen 5(gene name synonym)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:YPO3319(locus name)|uniprotkb:y0870(locus name)|uniprotkb:YP_0367(locus name)	psi-mi:scyl1_human(display_long)|uniprotkb:SCY1-like protein 1(gene name synonym)|uniprotkb:Teratoma-associated tyrosine kinase(gene name synonym)|uniprotkb:Telomerase transcriptional element-interacting factor(gene name synonym)|uniprotkb:Telomerase regulation-associated protein(gene name synonym)|uniprotkb:SCYL1(gene name)|psi-mi:SCYL1(display_short)|uniprotkb:Coated vesicle-associated kinase of 90 kDa(gene name synonym)|uniprotkb:CVAK90(gene name synonym)|uniprotkb:GKLP(gene name synonym)|uniprotkb:NTKL(gene name synonym)|uniprotkb:TAPK(gene name synonym)|uniprotkb:TEIF(gene name synonym)|uniprotkb:TRAP(gene name synonym)|uniprotkb:HT019(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862424|imex:IM-13779-6750	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|go:""GO:0004096""(catalase activity)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|refseq:WP_002209433.1|refseq:YP_002348215.1|panther:PTHR30555(orthology-group)"	"efo:""Orphanet:466794""|ensembl:ENSG00000142186.18(gene)|ensembl:ENST00000270176.10(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0006954""(inflammatory response)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0021522""(spinal cord motor neuron differentiation)|go:""GO:0030126""(COPI vesicle coat)|go:""GO:0045296""(cadherin binding)|go:""GO:0048666""(neuron development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR051177|mint:Q96KG9|refseq:NP_001041683.1|refseq:NP_065731.3|refseq:XP_005274177.1|panther:PTHR12984(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RBebELhpxkVGfQv9Ix9rW4jzmpE632	rogid:qHL7to7M3sjqepd3yuU1uo4Mhy49606	intact-crc:C4D6113138565C0C|rigid:BUWNVNYIBuMVcMDG2Hm2sXez0Lg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYH3	uniprotkb:P19338	intact:EBI-2842340|uniprotkb:Q74PE3|uniprotkb:Q0W9X2|uniprotkb:Q7CFQ3|uniprotkb:A0A5P8YAI4|uniprotkb:A0A384L096	intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195.4	psi-mi:a0a2u2gyh3_yerpe(display_long)|uniprotkb:fdoH(gene name)|psi-mi:fdoH(display_short)|uniprotkb:YPO4057(locus name)	psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862388|imex:IM-13779-6752	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR006470(Formate dehydrogenase, beta subunit)|interpro:IPR014603(Formate dehydrogenase, iron-sulphur subunit)|interpro:IPR015246(Formate dehydrogenase, transmembrane)|interpro:IPR017900|go:""GO:0005886""(plasma membrane)|go:""GO:0015944""(formate oxidation)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002209611.1|interpro:IPR038384|refseq:YP_002348916.1|interpro:IPR051555"	"refseq:NP_005372.2|dip:DIP-89N|panther:PTHR48034(orthology-group)|ensembl:ENSG00000115053.17(gene)|ensembl:ENST00000322723.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001533""(cornified envelope)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0042731""(PH domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0044547""(DNA topoisomerase binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0160056""(macropinosome membrane)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226|reactome:R-HSA-9820960"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:qUnsGukyBMEHq2jL5PYOvQ0betE632	rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606	intact-crc:91E55D333AAA3F9B|rigid:yXZiOtP5ZFquKwveGesZeWSX/xw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PJW4	uniprotkb:Q02297	intact:EBI-2847196|uniprotkb:Q0WI94|uniprotkb:Q7CGR6	intact:EBI-2460704|uniprotkb:B7Z4Z3|uniprotkb:E9PHH4|uniprotkb:A5YAK4|uniprotkb:A5YAK5|uniprotkb:O14667|uniprotkb:P98202|uniprotkb:Q02298|uniprotkb:Q02299|uniprotkb:Q07110|uniprotkb:Q07111|uniprotkb:Q12779|uniprotkb:Q12780|uniprotkb:Q12781|uniprotkb:Q12782|uniprotkb:Q12783|uniprotkb:Q12784|uniprotkb:Q15491|uniprotkb:Q7RTV9|uniprotkb:Q7RTW0|uniprotkb:Q7RTW1|uniprotkb:Q7RTW2|uniprotkb:Q8NFN1|uniprotkb:Q8NFN2|uniprotkb:Q8NFN3|uniprotkb:Q9UPE3|uniprotkb:A8K1L2|ensembl:ENSP00000384620.2	psi-mi:a0a380pjw4_yerpe(display_long)|uniprotkb:YPO0947(locus name)	psi-mi:nrg1_human(display_long)|uniprotkb:NRG1(gene name)|psi-mi:NRG1(display_short)|uniprotkb:GGF(gene name synonym)|uniprotkb:HGL(gene name synonym)|uniprotkb:HRGA(gene name synonym)|uniprotkb:NDF(gene name synonym)|uniprotkb:SMDF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862460|imex:IM-13779-6755	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020974|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|interpro:IPR028994|refseq:WP_002224905.1|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016740""(transferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR038383|refseq:YP_002345994.1|interpro:IPR049824"	"refseq:NP_001153467.1|refseq:NP_001153471.1|refseq:NP_001153473.1|refseq:NP_001153477.1|refseq:NP_039250.2|refseq:NP_039251.2|refseq:NP_039252.2|refseq:NP_039253.1|refseq:NP_039256.2|refseq:NP_039258.1|refseq:NP_001309134.1|refseq:NP_001309135.1|refseq:NP_001309136.1|refseq:NP_001153480.1|dip:DIP-355N|ensembl:ENSG00000157168.22(gene)|ensembl:ENST00000405005.8(transcript)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0007154""(cell communication)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007171""(activation of transmembrane receptor protein tyrosine kinase activity)|go:""GO:0007399""(nervous system development)|go:""GO:0007420""(brain development)|go:""GO:0007422""(peripheral nervous system development)|go:""GO:0008083""(growth factor activity)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0014032""(neural crest cell development)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030297""(transmembrane receptor protein tyrosine kinase activator activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030879""(mammary gland development)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032148""(activation of protein kinase B activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0038129""(ERBB3 signaling pathway)|go:""GO:0038130""(ERBB4 signaling pathway)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0038135""(ERBB2-ERBB4 signaling pathway)|go:""GO:0038138""(ERBB4-ERBB4 signaling pathway)|go:""GO:0042060""(wound healing)|go:""GO:0043125""(ErbB-3 class receptor binding)|go:""GO:0045499""(chemorepellent activity)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0051048""(negative regulation of secretion)|go:""GO:0051155""(positive regulation of striated muscle cell differentiation)|go:""GO:0051238""(obsolete sequestering of metal ion)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0055012""(ventricular cardiac muscle cell differentiation)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060956""(endocardial cell differentiation)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:1900086""(positive regulation of peptidyl-tyrosine autophosphorylation)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002154(Neuregulin 1-related, C-terminal)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018250|interpro:IPR036179|interpro:IPR040180|mint:Q02297|rcsb pdb:1HAE|rcsb pdb:1HAF|rcsb pdb:1HRE|rcsb pdb:1HRF|rcsb pdb:3U7U|rcsb pdb:7MN5|rcsb pdb:7MN6|rcsb pdb:7MN8|rcsb pdb:7SJL|rcsb pdb:8U4I|rcsb pdb:8U4L|reactome:R-HSA-1227986|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1250342|reactome:R-HSA-1250347|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-1306955|reactome:R-HSA-1358803|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8863795|reactome:R-HSA-9620244|reactome:R-HSA-9664565|reactome:R-HSA-9665686|refseq:NP_039254.1|panther:PTHR11100(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3Aj0qy9DiLKc8Bx9KbIJWyE+XAM632	rogid:J2CMur3i1USt6QII/qpk4+FmY1o9606	intact-crc:56550BADB1D2FC45|rigid:ejdtg8sXc8h+4rOIn1Wd3GvxdcE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6M0NJJ8	uniprotkb:Q96L73	intact:EBI-2859006	intact:EBI-2862434|uniprotkb:Q96PD8|uniprotkb:Q96RN7|ensembl:ENSP00000395929.2|intact:EBI-28969107	psi-mi:a0a6m0njj8_yerpe(display_long)|uniprotkb:zntA(gene name)|psi-mi:zntA(display_short)|uniprotkb:y0410(locus name)	psi-mi:nsd1_human(display_long)|uniprotkb:NSD1(gene name)|psi-mi:NSD1(display_short)|uniprotkb:ARA267(gene name synonym)|uniprotkb:KMT3B(gene name synonym)|uniprotkb:Androgen receptor coactivator 267 kDa protein(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 267 kDa(gene name synonym)|uniprotkb:H3-K36-HMTase(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3B(gene name synonym)|uniprotkb:Nuclear receptor-binding SET domain-containing protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862431|imex:IM-13779-6753	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T3U5(uniprot-removed-ac)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR017969|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR027256|interpro:IPR036163|interpro:IPR036412|interpro:IPR044492|interpro:IPR051014|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015662""(P-type ion transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019829""(ATPase-coupled monoatomic cation transmembrane transporter activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002231925.1"	"efo:""Orphanet:1627""|efo:""Orphanet:228415""|dip:DIP-58517N|ensembl:ENSG00000165671.22(gene)|ensembl:ENST00000439151.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0032259""(methylation)|go:""GO:0033135""(regulation of peptidyl-serine phosphorylation)|go:""GO:0042799""(histone H4K20 methyltransferase activity)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046975""(histone H3K36 methyltransferase activity)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0140938""(histone H3 methyltransferase activity)|go:""GO:0140954""(histone H3K36 dimethyltransferase activity)|go:""GO:1903025""(regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR041306|interpro:IPR046341|interpro:IPR047423|interpro:IPR047426|interpro:IPR047428|interpro:IPR047429|interpro:IPR047430|interpro:IPR047432|interpro:IPR047433|interpro:IPR050777|interpro:IPR055197|interpro:IPR055198|rcsb pdb:3OOI|rcsb pdb:6KQP|rcsb pdb:6KQQ|rcsb pdb:8C5L|reactome:R-HSA-3214841|refseq:NP_071900.2|refseq:NP_758859.1|efo:""Orphanet:3447""|efo:""Orphanet:821""|efo:""Orphanet:238613""|panther:PTHR22884(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/20	rogid:+CzYQMblOQc5YaMubF8rba/RSxo632	rogid:uuAFfvVmji0Q9ibKm5WSFgjJ/JQ9606	intact-crc:3CAE91574147FAA1|rigid:lbixRfCbHFWbNojiLj8RiY0ZLog	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZGB4	uniprotkb:O43847	intact:EBI-2862467|uniprotkb:Q0WH26	intact:EBI-2371631|uniprotkb:O15241|uniprotkb:O15242|uniprotkb:Q5VUL0|uniprotkb:Q96HB2|uniprotkb:Q9NU57|uniprotkb:A6NI41|intact:EBI-6137671|ensembl:ENSP00000262679.8	psi-mi:serc_yerpe(display_long)|uniprotkb:serC(gene name)|psi-mi:serC(display_short)|uniprotkb:Phosphohydroxythreonine aminotransferase(gene name synonym)|uniprotkb:YPO1389(locus name)|uniprotkb:y2784(locus name)|uniprotkb:YP_1204(locus name)	psi-mi:nrdc_human(display_long)|uniprotkb:NRDC(gene name)|psi-mi:NRDC(display_short)|uniprotkb:N-arginine dibasic convertase(gene name synonym)|uniprotkb:NRD1(gene name synonym)|uniprotkb:Nardilysin convertase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862472|imex:IM-13779-6757	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR020578|interpro:IPR022278|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002211326.1|go:""GO:0004648""(""O-phospho-L-serine:2-oxoglutarate aminotransferase activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006564""(L-serine biosynthetic process)|go:""GO:0008615""(pyridoxine biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:YP_002346412.1|panther:PTHR43247(orthology-group)"	"refseq:NP_001095132.1|refseq:NP_001229290.1|refseq:NP_002516.2|ensembl:ENSG00000078618.23(gene)|ensembl:ENST00000352171.12(transcript)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0009986""(cell surface)|go:""GO:0030425""(dendrite)|go:""GO:0031643""(positive regulation of myelination)|go:""GO:0046872""(metal ion binding)|go:""GO:0048408""(epidermal growth factor binding)|go:""GO:0050772""(positive regulation of axonogenesis)|go:""GO:0051044""(positive regulation of membrane protein ectodomain proteolysis)|go:""GO:0052548""(regulation of endopeptidase activity)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR032632|interpro:IPR050626|mint:O43847|panther:PTHR43690(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eCpuSZqJ46LMndvOWu1vUheV+QM632	rogid:zvZTk2Q799M8nsREOYmuYPF/x1U9606	intact-crc:B2DCED58C6FB0052|rigid:D563zCeAN3wXDsqeaW5DF+GQn20	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GUN8	uniprotkb:O14786	intact:EBI-2844713|uniprotkb:Q74T17|uniprotkb:Q0WDV8|uniprotkb:Q7CJ97|uniprotkb:A0A3N4AZU4|uniprotkb:A0A384KTX0	intact:EBI-1187100|uniprotkb:O60461|uniprotkb:Q96IH5|uniprotkb:Q5T7F2|uniprotkb:Q5T7F3|uniprotkb:B0LPG9|uniprotkb:Q86T59|uniprotkb:Q5T7F1|uniprotkb:Q96I90|ensembl:ENSP00000265371.3|ensembl:ENSP00000364001.2	psi-mi:a0a2u2gun8_yerpe(display_long)|uniprotkb:YPO2569(locus name)	psi-mi:nrp1_human(display_long)|uniprotkb:Vascular endothelial cell growth factor 165 receptor(gene name synonym)|uniprotkb:NRP1(gene name)|psi-mi:NRP1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:VEGF165R(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862453|imex:IM-13779-6754	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3OXP|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_002210291.1|go:""GO:0005737""(cytoplasm)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|refseq:YP_002347530.1|interpro:IPR051351"	"refseq:NP_001019800.1|refseq:NP_001019799.1|refseq:NP_003864.4|panther:PTHR46806(orthology-group)|refseq:NP_001316997.1|dip:DIP-5743N|rcsb pdb:2QQN|ensembl:ENSG00000099250.18(gene)|ensembl:ENST00000265371.8(transcript)|ensembl:ENST00000374867.7(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001569""(branching involved in blood vessel morphogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001755""(neural crest cell migration)|go:""GO:0001764""(neuron migration)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002116""(semaphorin receptor complex)|go:""GO:0003148""(outflow tract septum morphogenesis)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005883""(neurofilament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007165""(signal transduction)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007411""(axon guidance)|go:""GO:0007413""(axonal fasciculation)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008201""(heparin binding)|go:""GO:0009611""(response to wounding)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|rcsb pdb:3I97|go:""GO:0015026""(coreceptor activity)|go:""GO:0017154""(semaphorin receptor activity)|go:""GO:0019838""(growth factor binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0021612""(facial nerve structural organization)|go:""GO:0021637""(trigeminal nerve structural organization)|go:""GO:0021649""(vestibulocochlear nerve structural organization)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021828""(gonadotrophin-releasing hormone neuronal migration to the hypothalamus)|go:""GO:0030424""(axon)|go:""GO:0030947""(regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031290""(retinal ganglion cell axon guidance)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032489""(regulation of Cdc42 protein signal transduction)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0035767""(endothelial cell chemotaxis)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0036486""(ventral trunk neural crest cell migration)|go:""GO:0038085""(vascular endothelial growth factor binding)|go:""GO:0038189""(neuropilin signaling pathway)|go:""GO:0038190""(VEGF-activated neuropilin signaling pathway)|go:""GO:0043005""(neuron projection)|go:""GO:0043235""(receptor complex)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048012""(hepatocyte growth factor receptor signaling pathway)|go:""GO:0048842""(positive regulation of axon extension involved in axon guidance)|go:""GO:0048843""(negative regulation of axon extension involved in axon guidance)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0048846""(axon extension involved in axon guidance)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051491""(positive regulation of filopodium assembly)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0060385""(axonogenesis involved in innervation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0060666""(dichotomous subdivision of terminal units involved in salivary gland branching)|go:""GO:0060978""(angiogenesis involved in coronary vascular morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061299""(retina vasculature morphogenesis in camera-type eye)|go:""GO:0061441""(renal artery morphogenesis)|go:""GO:0061549""(sympathetic ganglion development)|go:""GO:0061551""(trigeminal ganglion development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0071679""(commissural neuron axon guidance)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0097102""(endothelial tip cell fate specification)|go:""GO:0097374""(sensory neuron axon guidance)|go:""GO:0097443""(sorting endosome)|go:""GO:0097475""(motor neuron migration)|go:""GO:0097490""(sympathetic neuron projection extension)|go:""GO:0097491""(sympathetic neuron projection guidance)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099173""(postsynapse organization)|go:""GO:0150018""(basal dendrite development)|go:""GO:0150020""(basal dendrite arborization)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901166""(neural crest cell migration involved in autonomic nervous system development)|go:""GO:1902946""(protein localization to early endosome)|go:""GO:1903375""(facioacoustic ganglion development)|go:""GO:1904835""(dorsal root ganglion morphogenesis)|go:""GO:1905040""(otic placode development)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000859(CUB)|interpro:IPR000998(MAM)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014648(Neuropilin)|interpro:IPR022579|interpro:IPR035914|interpro:IPR050633|mint:O14786|rcsb pdb:1KEX|rcsb pdb:2QQI|rcsb pdb:2QQM|rcsb pdb:4DEQ|rcsb pdb:4RN5|rcsb pdb:5C7G|rcsb pdb:5IJR|rcsb pdb:5IYY|rcsb pdb:5J1X|rcsb pdb:5JGI|rcsb pdb:5JGQ|rcsb pdb:5JHK|rcsb pdb:5L73|rcsb pdb:6FMC|rcsb pdb:6FMF|rcsb pdb:6TKK|rcsb pdb:7JJC|rcsb pdb:7O1N|rcsb pdb:7P5U|rcsb pdb:8C5G|rcsb pdb:8PFE|rcsb pdb:9EOU|reactome:R-HSA-194306|reactome:R-HSA-376176|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-445144|reactome:R-HSA-447041|reactome:R-HSA-9694614"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:WexLHH5KTrnggqyPy38AGIRlsdI632	rogid:q8i8R/AetWNGkscqBWAJPHhmF+E9606	intact-crc:7779C8DA1FAAFF70|rigid:27m86DBs1fvuj0VH5UD6PK9CFOM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96L73	uniprotkb:Q8ZA76	intact:EBI-2862434|uniprotkb:Q96PD8|uniprotkb:Q96RN7|ensembl:ENSP00000395929.2|intact:EBI-28969107	intact:EBI-2846943|uniprotkb:Q0WA76	psi-mi:nsd1_human(display_long)|uniprotkb:NSD1(gene name)|psi-mi:NSD1(display_short)|uniprotkb:ARA267(gene name synonym)|uniprotkb:KMT3B(gene name synonym)|uniprotkb:Androgen receptor coactivator 267 kDa protein(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 267 kDa(gene name synonym)|uniprotkb:H3-K36-HMTase(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3B(gene name synonym)|uniprotkb:Nuclear receptor-binding SET domain-containing protein 1(gene name synonym)	psi-mi:glgx_yerpe(display_long)|uniprotkb:glgX(gene name)|psi-mi:glgX(display_short)|uniprotkb:Limit dextrin alpha-1,6-maltotetraose-hydrolase(gene name synonym)|uniprotkb:YPO3941(locus name)|uniprotkb:YP_3303(locus name)|uniprotkb:y3887(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862446|imex:IM-13779-6756	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1627""|efo:""Orphanet:228415""|dip:DIP-58517N|ensembl:ENSG00000165671.22(gene)|ensembl:ENST00000439151.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0032259""(methylation)|go:""GO:0033135""(regulation of peptidyl-serine phosphorylation)|go:""GO:0042799""(histone H4K20 methyltransferase activity)|go:""GO:0042974""(nuclear retinoic acid receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046975""(histone H3K36 methyltransferase activity)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0140938""(histone H3 methyltransferase activity)|go:""GO:0140954""(histone H3K36 dimethyltransferase activity)|go:""GO:1903025""(regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR041306|interpro:IPR046341|interpro:IPR047423|interpro:IPR047426|interpro:IPR047428|interpro:IPR047429|interpro:IPR047430|interpro:IPR047432|interpro:IPR047433|interpro:IPR050777|interpro:IPR055197|interpro:IPR055198|rcsb pdb:3OOI|rcsb pdb:6KQP|rcsb pdb:6KQQ|rcsb pdb:8C5L|reactome:R-HSA-3214841|refseq:NP_071900.2|refseq:NP_758859.1|efo:""Orphanet:3447""|efo:""Orphanet:821""|efo:""Orphanet:238613""|panther:PTHR22884(orthology-group)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR022844|interpro:IPR011837(Glycogen debranching enzyme GlgX)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR040784|go:""GO:0004133""(obsolete glycogen debranching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005980""(glycogen catabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_002209499.1|interpro:IPR044505|refseq:YP_002348812.1|panther:PTHR43002(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/20	rogid:uuAFfvVmji0Q9ibKm5WSFgjJ/JQ9606	rogid:8sHtj0obGqvrIdGE1JWk8okcbRM632	intact-crc:F82AA9796590B8CF|rigid:txhp/ufcHLMkAlwGveQmS6UJG4I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZB88	uniprotkb:P16083	intact:EBI-2862486|uniprotkb:Q74X98|uniprotkb:Q0WBB8|uniprotkb:Q7CKL0	intact:EBI-358466|uniprotkb:B2R492|uniprotkb:Q5TD04|ensembl:ENSP00000337773.2|ensembl:ENSP00000369795.1|ensembl:ENSP00000369822.4	psi-mi:ytfe_yerpe(display_long)|uniprotkb:ytfE(gene name)|psi-mi:ytfE(display_short)|uniprotkb:YPO3531(locus name)|uniprotkb:y0652(locus name)|uniprotkb:YP_0552(locus name)	"psi-mi:nqo2_human(display_long)|uniprotkb:NQO2(gene name)|psi-mi:NQO2(display_short)|uniprotkb:NMOR2(gene name synonym)|uniprotkb:NRH dehydrogenase [quinone] 2(gene name synonym)|uniprotkb:""NRH:quinone oxidoreductase 2""(gene name synonym)|uniprotkb:Quinone reductase 2(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862492|imex:IM-13779-6758	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023742|interpro:IPR012312(Hemerythrin/HHE cation-binding motif)|interpro:IPR019903|refseq:WP_002210159.1|go:""GO:0005737""(cytoplasm)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0030091""(protein repair)|go:""GO:0046872""(metal ion binding)|go:""GO:0051409""(response to nitrosative stress)|refseq:YP_002348420.1|panther:PTHR36438(orthology-group)"	"ensembl:ENSG00000124588.22(gene)|ensembl:ENST00000338130.7(transcript)|ensembl:ENST00000380430.6(transcript)|ensembl:ENST00000380455.11(transcript)|go:""GO:0001512""(dihydronicotinamide riboside quinone reductase activity)|go:""GO:0003955""(""NAD(P)H dehydrogenase (quinone) activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009055""(electron transfer activity)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016661""(oxidoreductase activity, acting on other nitrogenous compounds as donors)|go:""GO:0031404""(chloride ion binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071949""(FAD binding)|go:""GO:1901662""(quinone catabolic process)|go:""GO:1904408""(melatonin binding)|go:""GO:1905594""(resveratrol binding)|interpro:IPR003680(Flavodoxin-like fold)|interpro:IPR029039|interpro:IPR051545|mint:P16083|rcsb pdb:1QR2|rcsb pdb:1SG0|rcsb pdb:1XI2|rcsb pdb:1ZX1|rcsb pdb:2BZS|rcsb pdb:2QMY|rcsb pdb:2QMZ|rcsb pdb:2QR2|rcsb pdb:2QWX|rcsb pdb:2QX4|rcsb pdb:2QX6|rcsb pdb:2QX8|rcsb pdb:2QX9|rcsb pdb:3FW1|rcsb pdb:3G5M|rcsb pdb:3GAM|rcsb pdb:3NFR|rcsb pdb:3NHF|rcsb pdb:3NHJ|rcsb pdb:3NHK|rcsb pdb:3NHL|rcsb pdb:3NHP|rcsb pdb:3NHR|rcsb pdb:3NHS|rcsb pdb:3NHU|rcsb pdb:3NHW|rcsb pdb:3NHY|rcsb pdb:3O2N|rcsb pdb:3O73|rcsb pdb:3OVM|rcsb pdb:3OWH|rcsb pdb:3OWX|rcsb pdb:3OX1|rcsb pdb:3OX2|rcsb pdb:3OX3|rcsb pdb:3TE7|rcsb pdb:3TEM|rcsb pdb:3TZB|rcsb pdb:3UXE|rcsb pdb:3UXH|rcsb pdb:4FGJ|rcsb pdb:4FGK|rcsb pdb:4FGL|rcsb pdb:4GQI|rcsb pdb:4GR9|rcsb pdb:4QOD|rcsb pdb:4QOE|rcsb pdb:4QOF|rcsb pdb:4QOG|rcsb pdb:4QOH|rcsb pdb:4QOI|rcsb pdb:4QOJ|rcsb pdb:4U7F|rcsb pdb:4U7G|rcsb pdb:4U7H|rcsb pdb:4XDG|rcsb pdb:4XDH|rcsb pdb:4ZVK|rcsb pdb:4ZVL|rcsb pdb:4ZVM|rcsb pdb:4ZVN|rcsb pdb:5BUC|rcsb pdb:5LBT|rcsb pdb:5LBU|rcsb pdb:5LBW|rcsb pdb:5LBY|rcsb pdb:5LBZ|rcsb pdb:7O4D|reactome:R-HSA-211945|refseq:NP_000895.2|refseq:NP_001277150.1|refseq:NP_001305869.1|efo:""Orphanet:227535""|dip:DIP-39704N|panther:PTHR10204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:SiGkh570anfI/nqCqh5ZsozkA0U632	rogid:e23niMWdj6fUH4WR3K6sUCTM0KE9606	intact-crc:9A25195DC874B1A6|rigid:mYcAUQ3V3xzUg4RSpKbuIl65YEY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZM5	uniprotkb:Q14994	intact:EBI-2842364	intact:EBI-960794|uniprotkb:E9PB75|uniprotkb:E9PC13|uniprotkb:E9PDU3|uniprotkb:E9PHC8|uniprotkb:Q6GZ76|uniprotkb:Q6GZ79|uniprotkb:Q6GZ82|uniprotkb:Q6GZ89|uniprotkb:E9PGH6|uniprotkb:E9PH10|uniprotkb:Q5VTW5|uniprotkb:Q5VTW6|uniprotkb:E9PHN4|uniprotkb:Q6GZ77|uniprotkb:Q6GZ78|uniprotkb:Q6GZ83|uniprotkb:F1D8Q0|uniprotkb:F1D8Q1|uniprotkb:Q0VAC9|uniprotkb:Q6GZ68|uniprotkb:Q6GZ84|uniprotkb:Q6GZ87|uniprotkb:Q6GZ85|uniprotkb:Q4U0F0|ensembl:ENSP00000356961.4	psi-mi:q8czm5_yerpe(display_long)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short)|uniprotkb:y3804(locus name)	psi-mi:nr1i3_human(display_long)|uniprotkb:NR1I3(gene name)|psi-mi:NR1I3(display_short)|uniprotkb:CAR(gene name synonym)|uniprotkb:Constitutive androstane receptor(gene name synonym)|uniprotkb:Constitutive activator of retinoid response(gene name synonym)|uniprotkb:Orphan nuclear receptor MB67(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862479|imex:IM-13779-6762	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR027302|interpro:IPR027303|go:""GO:0004356""(glutamine synthetase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006542""(glutamine biosynthetic process)|interpro:IPR036651"	"refseq:NP_001070941.1|refseq:NP_001070944.1|refseq:NP_001070945.1|refseq:NP_001070948.1|refseq:NP_005113.1|refseq:NP_001070937.1|refseq:NP_001070942.1|refseq:NP_001070943.1|refseq:NP_001070946.1|refseq:NP_001070938.1|refseq:NP_001070940.1|refseq:NP_001070947.1|refseq:NP_001070949.1|refseq:NP_001070950.1|refseq:NP_001070939.1|ensembl:ENSG00000143257.12(gene)|ensembl:ENST00000367982.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0004879""(nuclear receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007165""(signal transduction)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR050234|rcsb pdb:1XV9|rcsb pdb:1XVP|reactome:R-HSA-383280|panther:PTHR24082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1UHMOyirOEgP8E+d/TNK/YRPS+4632	rogid:O7jzKsV+T6ebbQQTaZq0xYiqls89606	intact-crc:8B7257FCC0A053BA|rigid:VwQqKgOQZUs+lk/MKl8OPg2WS+c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GXH7	uniprotkb:Q9UFN0	intact:EBI-2848470|uniprotkb:Q74WH6|uniprotkb:Q0WHG3|uniprotkb:A0A0H2W2J4|uniprotkb:Q7CHB5|uniprotkb:A0A384K9G2	intact:EBI-716291|uniprotkb:A6NM55|uniprotkb:Q5VX32|uniprotkb:Q9BRV7|uniprotkb:Q9H843|uniprotkb:Q9P083|ensembl:ENSP00000363899.4	psi-mi:a0a2u2gxh7_yerpe(display_long)|uniprotkb:YPO1246(locus name)	psi-mi:nps3a_human(display_long)|uniprotkb:Protein NipSnap homolog 4(gene name synonym)|uniprotkb:Target for Salmonella secreted protein C(gene name synonym)|uniprotkb:NIPSNAP3A(gene name)|psi-mi:NIPSNAP3A(display_short)|uniprotkb:NIPSNAP4(gene name synonym)|uniprotkb:HSPC299(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862511|imex:IM-13779-6759	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR009826(DNA circulation, N-terminal)|refseq:WP_002208852.1|refseq:YP_002346275.1|interpro:IPR052399	"refseq:NP_056284.1|refseq:NP_001316499.1|ensembl:ENSG00000136783.10(gene)|ensembl:ENST00000374767.5(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|interpro:IPR051557|mint:Q9UFN0|panther:PTHR21017(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Qbi9eC3jfsnnPhDaTUvn+57rY7s632	rogid:A+TeCcZCRDx0YyqwnG8xJQLq0Jw9606	intact-crc:A57FE7DDCDC1FA08|rigid:nbOVGYEqJuDOIBJTGlPsgbv2Xyg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5KZU3	uniprotkb:P06748	intact:EBI-2850940	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:a0a3g5kzu3_yerpe(display_long)|uniprotkb:y0245(locus name)|uniprotkb:ssuA(gene name)|psi-mi:ssuA(display_short)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862518|imex:IM-13779-6760	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR010067(ABC transporter, substrate-binding protein, aliphatic sulphonates)|interpro:IPR015168(NMT1/THI5 like)|uniprotkb:A0A6B3T643(uniprot-removed-ac)|go:""GO:0016020""(membrane)|go:""GO:0042597""(periplasmic space)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|refseq:WP_002220949.1"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kuMqjHfkYUIBJ4hy+1j+bwqjjo4632	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:B38ECB9FB3B0D127|rigid:Fz1E/vK/6QkXcJtHISQBxZFh6iA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PKI3	uniprotkb:P16083	intact:EBI-2862502|uniprotkb:Q74QW7|uniprotkb:Q0WA43|uniprotkb:Q7CG05|uniprotkb:A0A384KV46	intact:EBI-358466|uniprotkb:B2R492|uniprotkb:Q5TD04|ensembl:ENSP00000337773.2|ensembl:ENSP00000369795.1|ensembl:ENSP00000369822.4	psi-mi:a0a2s9pki3_yerpe(display_long)|uniprotkb:opdA(gene name)|psi-mi:opdA(display_short)|uniprotkb:prlC(gene name synonym)|uniprotkb:YPO3975(locus name)	"psi-mi:nqo2_human(display_long)|uniprotkb:NQO2(gene name)|psi-mi:NQO2(display_short)|uniprotkb:NMOR2(gene name synonym)|uniprotkb:NRH dehydrogenase [quinone] 2(gene name synonym)|uniprotkb:""NRH:quinone oxidoreductase 2""(gene name synonym)|uniprotkb:Quinone reductase 2(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862499|imex:IM-13779-6761	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|interpro:IPR024079|interpro:IPR024080|refseq:WP_002209531.1|interpro:IPR024077|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006508""(proteolysis)|go:""GO:0006518""(peptide metabolic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_002348845.1|interpro:IPR034005|interpro:IPR045090|interpro:IPR045666|panther:PTHR11804(orthology-group)"	"ensembl:ENSG00000124588.22(gene)|ensembl:ENST00000338130.7(transcript)|ensembl:ENST00000380430.6(transcript)|ensembl:ENST00000380455.11(transcript)|go:""GO:0001512""(dihydronicotinamide riboside quinone reductase activity)|go:""GO:0003955""(""NAD(P)H dehydrogenase (quinone) activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009055""(electron transfer activity)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016661""(oxidoreductase activity, acting on other nitrogenous compounds as donors)|go:""GO:0031404""(chloride ion binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071949""(FAD binding)|go:""GO:1901662""(quinone catabolic process)|go:""GO:1904408""(melatonin binding)|go:""GO:1905594""(resveratrol binding)|interpro:IPR003680(Flavodoxin-like fold)|interpro:IPR029039|interpro:IPR051545|mint:P16083|rcsb pdb:1QR2|rcsb pdb:1SG0|rcsb pdb:1XI2|rcsb pdb:1ZX1|rcsb pdb:2BZS|rcsb pdb:2QMY|rcsb pdb:2QMZ|rcsb pdb:2QR2|rcsb pdb:2QWX|rcsb pdb:2QX4|rcsb pdb:2QX6|rcsb pdb:2QX8|rcsb pdb:2QX9|rcsb pdb:3FW1|rcsb pdb:3G5M|rcsb pdb:3GAM|rcsb pdb:3NFR|rcsb pdb:3NHF|rcsb pdb:3NHJ|rcsb pdb:3NHK|rcsb pdb:3NHL|rcsb pdb:3NHP|rcsb pdb:3NHR|rcsb pdb:3NHS|rcsb pdb:3NHU|rcsb pdb:3NHW|rcsb pdb:3NHY|rcsb pdb:3O2N|rcsb pdb:3O73|rcsb pdb:3OVM|rcsb pdb:3OWH|rcsb pdb:3OWX|rcsb pdb:3OX1|rcsb pdb:3OX2|rcsb pdb:3OX3|rcsb pdb:3TE7|rcsb pdb:3TEM|rcsb pdb:3TZB|rcsb pdb:3UXE|rcsb pdb:3UXH|rcsb pdb:4FGJ|rcsb pdb:4FGK|rcsb pdb:4FGL|rcsb pdb:4GQI|rcsb pdb:4GR9|rcsb pdb:4QOD|rcsb pdb:4QOE|rcsb pdb:4QOF|rcsb pdb:4QOG|rcsb pdb:4QOH|rcsb pdb:4QOI|rcsb pdb:4QOJ|rcsb pdb:4U7F|rcsb pdb:4U7G|rcsb pdb:4U7H|rcsb pdb:4XDG|rcsb pdb:4XDH|rcsb pdb:4ZVK|rcsb pdb:4ZVL|rcsb pdb:4ZVM|rcsb pdb:4ZVN|rcsb pdb:5BUC|rcsb pdb:5LBT|rcsb pdb:5LBU|rcsb pdb:5LBW|rcsb pdb:5LBY|rcsb pdb:5LBZ|rcsb pdb:7O4D|reactome:R-HSA-211945|refseq:NP_000895.2|refseq:NP_001277150.1|refseq:NP_001305869.1|efo:""Orphanet:227535""|dip:DIP-39704N|panther:PTHR10204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:WnrI1tgdtIgOsa/jFZ+jnh7mKmQ632	rogid:e23niMWdj6fUH4WR3K6sUCTM0KE9606	intact-crc:D47F7AA9609057EF|rigid:MTMBa34aK8Y59bA+ll/VDzqA5Gg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UM47	uniprotkb:Q8D176	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388.1	intact:EBI-2842041	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	psi-mi:q8d176_yerpe(display_long)|uniprotkb:y0939(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862553|imex:IM-13779-6767	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:136""|efo:""Orphanet:2591""|efo:""Orphanet:2789""|ensembl:ENSG00000074181.9(gene)|ensembl:ENST00000263388.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0009986""(cell surface)|go:""GO:0014016""(neuroblast differentiation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030900""(forebrain development)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048663""(neuron fate commitment)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0072104""(glomerular capillary formation)|go:""GO:1902895""(positive regulation of miRNA transcription)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|rcsb pdb:6XSW|rcsb pdb:8OS0|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802|refseq:NP_000426.2|dip:DIP-39827N|panther:PTHR45836(orthology-group)"	"interpro:IPR010158(Amidase, hydantoinase/carbamoylase)|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|go:""GO:0016813""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"")|go:""GO:0046872""(metal ion binding)|interpro:IPR036264"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	rogid:/GOJxJQAHqgWtVu6otA2a4TvHfI632	intact-crc:E50FAC153C259E30|rigid:xqRWIUWQkynJJ9Y1LqyVmP7Ozes	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86UR1	uniprotkb:Q8D0R4	intact:EBI-949814|uniprotkb:O60533|uniprotkb:Q29VU9|uniprotkb:Q29VV0|uniprotkb:Q2TAM1|uniprotkb:Q8IUS3|ensembl:ENSP00000507846.1	intact:EBI-2861358|uniprotkb:Q74T93	psi-mi:noxa1_human(display_long)|uniprotkb:NCF2-like protein(gene name synonym)|uniprotkb:Antigen NY-CO-31(gene name synonym)|uniprotkb:P67phox-like factor(gene name synonym)|uniprotkb:p51-nox(gene name synonym)|uniprotkb:NOXA1(gene name)|psi-mi:NOXA1(display_short)|uniprotkb:P51NOX(gene name synonym)	psi-mi:q8d0r4_yerpe(display_long)|uniprotkb:ugpB3(gene name)|psi-mi:ugpB3(display_short)|uniprotkb:YP_2296(locus name)|uniprotkb:y1712(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862539|imex:IM-13779-6764	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006638.1|refseq:NP_001242996.1|refseq:NP_001242997.1|ensembl:ENSG00000188747.9(gene)|ensembl:ENST00000683555.1(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006801""(superoxide metabolic process)|go:""GO:0010310""(regulation of hydrogen peroxide metabolic process)|go:""GO:0016176""(superoxide-generating NADPH oxidase activator activity)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019899""(enzyme binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0042554""(superoxide anion generation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043020""(NADPH oxidase complex)|go:""GO:0060263""(regulation of respiratory burst)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001452(Src homology-3)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR036028|interpro:IPR051864|interpro:IPR053793|mint:Q86UR1|rcsb pdb:7CFZ|reactome:R-HSA-5668599|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9673324|panther:PTHR15175(orthology-group)"	"interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR050490|go:""GO:0016020""(membrane)|go:""GO:0030313""(cell envelope)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:b9yF3AbB0i4feLHukYPjiT5jlJg9606	rogid:WdQAdof8UnHcq+RBx3s9B0uCIlM632	intact-crc:08E6F5D76CF02D95|rigid:EHYsraRlw/E6FPwYzpAXrR293Ac	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:P06748	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862525|imex:IM-13779-6763	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:B5EDCA8E48AAC660|rigid:K1WF05iWd3ZVclzdPmb/eIXJJpQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZFR1	uniprotkb:P06748	intact:EBI-2845635|uniprotkb:Q0WGE7	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:npd_yerpe(display_long)|uniprotkb:cobB(gene name)|psi-mi:cobB(display_short)|uniprotkb:Regulatory protein SIR2 homolog(gene name synonym)|uniprotkb:YPO1630(locus name)|uniprotkb:y1790(locus name)|uniprotkb:YP_1760(locus name)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862532|imex:IM-13779-6766	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR027546|interpro:IPR029035|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0017136""(histone deacetylase activity, NAD-dependent)|go:""GO:0032041""(histone H3K14 deacetylase activity, NAD-dependent)|go:""GO:0036054""(protein-malonyllysine demalonylase activity)|go:""GO:0036055""(protein-succinyllysine desuccinylase activity)|go:""GO:0046969""(histone H3K9 deacetylase activity, NAD-dependent)|go:""GO:0046970""(histone H4K16 deacetylase activity, NAD-dependent)|go:""GO:0070403""(NAD+ binding)|go:""GO:0097372""(histone H3K18 deacetylase activity, NAD-dependent)|go:""GO:0140765""(histone H3K56 deacetylase activity, NAD-dependent)|go:""GO:0141222""(histone H3K4 deacetylase activity, NAD-dependent)|go:""GO:0160013""(NAD-dependent protein de-2-hydroxyisobutyrylase activity)|refseq:WP_002210921.1|interpro:IPR026591|refseq:YP_002346641.1|interpro:IPR050134|panther:PTHR11085(orthology-group)"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Vx6TsEbqJmwcaje73uVtMzJ0+QA632	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:5D13F17C971739DD|rigid:nK8PdJxKRe+jwT14KpVCKJ1edBQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UM47	uniprotkb:Q8D1M6	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388.1	intact:EBI-2843280|uniprotkb:Q74PG5	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	psi-mi:q8d1m6_yerpe(display_long)|uniprotkb:rhsA5(gene name)|psi-mi:rhsA5(display_short)|uniprotkb:YP_3942(locus name)|uniprotkb:y0266(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862546|imex:IM-13779-6765	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:136""|efo:""Orphanet:2591""|efo:""Orphanet:2789""|ensembl:ENSG00000074181.9(gene)|ensembl:ENST00000263388.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0009986""(cell surface)|go:""GO:0014016""(neuroblast differentiation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030900""(forebrain development)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048663""(neuron fate commitment)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0072104""(glomerular capillary formation)|go:""GO:1902895""(positive regulation of miRNA transcription)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|rcsb pdb:6XSW|rcsb pdb:8OS0|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802|refseq:NP_000426.2|dip:DIP-39827N|panther:PTHR45836(orthology-group)"	"interpro:IPR008727(PAAR)|interpro:IPR006530(YD repeat)|go:""GO:0016020""(membrane)|interpro:IPR031325|interpro:IPR050708|interpro:IPR045351"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	rogid:VlaAlPegIR+u4FGQRAHV0zIR3S4632	intact-crc:7F35AC153C35301C|rigid:Cfz4V1W3J8fXuFZoAOA1rM4fS1g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCW0	uniprotkb:P46531	intact:EBI-2842923|uniprotkb:Q7CJK9|uniprotkb:Q0WD52|uniprotkb:Q74SA7	intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587.1	psi-mi:mdtb_yerpe(display_long)|uniprotkb:mdtB(gene name)|psi-mi:mdtB(display_short)|uniprotkb:Multidrug transporter MdtB(gene name synonym)|uniprotkb:YPO2848(locus name)|uniprotkb:y1385(locus name)|uniprotkb:YP_2715(locus name)	psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862588|imex:IM-13779-6770	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR022831|interpro:IPR027463|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:WP_002209793.1|refseq:YP_002347786.1|panther:PTHR32063(orthology-group)"	"ensembl:ENSG00000148400.13(gene)|ensembl:ENST00000651671.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001554""(luteolysis)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001889""(liver development)|go:""GO:0001947""(heart looping)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0002085""(inhibition of neuroepithelial cell differentiation)|go:""GO:0002193""(MAML1-RBP-Jkappa- ICN1 complex)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003157""(endocardium development)|go:""GO:0003160""(endocardium morphogenesis)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003169""(coronary vein morphogenesis)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0003182""(coronary sinus valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003192""(mitral valve formation)|go:""GO:0003198""(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003207""(cardiac chamber formation)|go:""GO:0003208""(cardiac ventricle morphogenesis)|go:""GO:0003209""(cardiac atrium morphogenesis)|go:""GO:0003213""(cardiac right atrium morphogenesis)|go:""GO:0003214""(cardiac left ventricle morphogenesis)|go:""GO:0003219""(cardiac right ventricle formation)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003241""(growth involved in heart morphogenesis)|go:""GO:0003252""(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:""GO:0003270""(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:""GO:0003273""(cell migration involved in endocardial cushion formation)|go:""GO:0003332""(negative regulation of extracellular matrix constituent secretion)|go:""GO:0003344""(pericardium morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007221""(positive regulation of transcription of Notch receptor target)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007386""(compartment pattern specification)|go:""GO:0007411""(axon guidance)|go:""GO:0007440""(foregut morphogenesis)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009912""(auditory receptor cell fate commitment)|go:""GO:0009957""(epidermal cell fate specification)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010614""(negative regulation of cardiac muscle hypertrophy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010832""(negative regulation of myotube differentiation)|go:""GO:0014031""(mesenchymal cell development)|go:""GO:0014807""(regulation of somitogenesis)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0019899""(enzyme binding)|go:""GO:0021515""(cell differentiation in spinal cord)|go:""GO:0021915""(neural tube development)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030900""(forebrain development)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032966""(negative regulation of collagen biosynthetic process)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035148""(tube formation)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042670""(retinal cone cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045603""(positive regulation of endothelial cell differentiation)|go:""GO:0045608""(negative regulation of inner ear auditory receptor cell differentiation)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045955""(negative regulation of calcium ion-dependent exocytosis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046533""(negative regulation of photoreceptor cell differentiation)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0048103""(somatic stem cell division)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048711""(positive regulation of astrocyte differentiation)|go:""GO:0048715""(negative regulation of oligodendrocyte differentiation)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0055008""(cardiac muscle tissue morphogenesis)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060271""(cilium assembly)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0060354""(negative regulation of cell adhesion molecule production)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060528""(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:""GO:0060740""(prostate gland epithelium morphogenesis)|go:""GO:0060768""(regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:0060842""(arterial endothelial cell differentiation)|go:""GO:0060843""(venous endothelial cell differentiation)|go:""GO:0060948""(cardiac vascular smooth muscle cell development)|go:""GO:0060956""(endocardial cell differentiation)|go:""GO:0060979""(vasculogenesis involved in coronary vascular morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061101""(neuroendocrine cell differentiation)|go:""GO:0061344""(regulation of cell adhesion involved in heart morphogenesis)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0062043""(positive regulation of cardiac epithelial to mesenchymal transition)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0071372""(cellular response to follicle-stimulating hormone stimulus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072017""(distal tubule development)|go:""GO:0072044""(collecting duct development)|go:""GO:0072091""(regulation of stem cell proliferation)|go:""GO:0072144""(glomerular mesangial cell development)|go:""GO:0072148""(epithelial cell fate commitment)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0097400""(interleukin-17-mediated signaling pathway)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099565""(chemical synaptic transmission, postsynaptic)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:1901201""(regulation of extracellular matrix assembly)|go:""GO:1902263""(apoptotic process involved in embryonic digit morphogenesis)|go:""GO:1902339""(positive regulation of apoptotic process involved in morphogenesis)|go:""GO:1903849""(positive regulation of aorta morphogenesis)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2000974""(negative regulation of pro-B cell differentiation)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|rcsb pdb:1PB5|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:P46531|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|rcsb pdb:8OR5|rcsb pdb:8ORY|rcsb pdb:8ORZ|rcsb pdb:9B3G|rcsb pdb:9B3N|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|reactome:R-HSA-9818030|reactome:R-HSA-9818749|reactome:R-HSA-9824272|refseq:NP_060087.3|dip:DIP-29919N|efo:""Orphanet:402075""|efo:""Orphanet:974""|panther:PTHR45836(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:LHw1WKWrAW5/xlsQ5C6WVb5Ua3M632	rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606	intact-crc:1A17FAF437C8D5E7|rigid:uZTIHw9FZo0tCVoXRG39VTR9lfQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CFY4	uniprotkb:P46531	intact:EBI-2839980|uniprotkb:Q0WA73	intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587.1	psi-mi:q7cfy4_yerpe(display_long)|uniprotkb:YPO3944(locus name)	psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862581|imex:IM-13779-6769	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003344(Bacterial Ig-like, group 1)|interpro:IPR024519|interpro:IPR003535(Intimin bacterial adhesion mediator protein)|interpro:IPR008964(Invasin/intimin cell-adhesion)|interpro:IPR018392|refseq:YP_002348815.1|interpro:IPR016186(C-type lectin-like)|interpro:IPR048658|go:""GO:0007155""(cell adhesion)|go:""GO:0009279""(cell outer membrane)|interpro:IPR038177|refseq:WP_002228169.1|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036779|interpro:IPR051715|panther:PTHR39576(orthology-group)"	"ensembl:ENSG00000148400.13(gene)|ensembl:ENST00000651671.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001554""(luteolysis)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001889""(liver development)|go:""GO:0001947""(heart looping)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0002085""(inhibition of neuroepithelial cell differentiation)|go:""GO:0002193""(MAML1-RBP-Jkappa- ICN1 complex)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003157""(endocardium development)|go:""GO:0003160""(endocardium morphogenesis)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003169""(coronary vein morphogenesis)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0003182""(coronary sinus valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003192""(mitral valve formation)|go:""GO:0003198""(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003207""(cardiac chamber formation)|go:""GO:0003208""(cardiac ventricle morphogenesis)|go:""GO:0003209""(cardiac atrium morphogenesis)|go:""GO:0003213""(cardiac right atrium morphogenesis)|go:""GO:0003214""(cardiac left ventricle morphogenesis)|go:""GO:0003219""(cardiac right ventricle formation)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003241""(growth involved in heart morphogenesis)|go:""GO:0003252""(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:""GO:0003270""(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:""GO:0003273""(cell migration involved in endocardial cushion formation)|go:""GO:0003332""(negative regulation of extracellular matrix constituent secretion)|go:""GO:0003344""(pericardium morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007221""(positive regulation of transcription of Notch receptor target)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007386""(compartment pattern specification)|go:""GO:0007411""(axon guidance)|go:""GO:0007440""(foregut morphogenesis)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009912""(auditory receptor cell fate commitment)|go:""GO:0009957""(epidermal cell fate specification)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010614""(negative regulation of cardiac muscle hypertrophy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010832""(negative regulation of myotube differentiation)|go:""GO:0014031""(mesenchymal cell development)|go:""GO:0014807""(regulation of somitogenesis)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0019899""(enzyme binding)|go:""GO:0021515""(cell differentiation in spinal cord)|go:""GO:0021915""(neural tube development)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030900""(forebrain development)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032966""(negative regulation of collagen biosynthetic process)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035148""(tube formation)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042670""(retinal cone cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045603""(positive regulation of endothelial cell differentiation)|go:""GO:0045608""(negative regulation of inner ear auditory receptor cell differentiation)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045955""(negative regulation of calcium ion-dependent exocytosis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046533""(negative regulation of photoreceptor cell differentiation)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0048103""(somatic stem cell division)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048711""(positive regulation of astrocyte differentiation)|go:""GO:0048715""(negative regulation of oligodendrocyte differentiation)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0055008""(cardiac muscle tissue morphogenesis)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060271""(cilium assembly)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0060354""(negative regulation of cell adhesion molecule production)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060528""(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:""GO:0060740""(prostate gland epithelium morphogenesis)|go:""GO:0060768""(regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:0060842""(arterial endothelial cell differentiation)|go:""GO:0060843""(venous endothelial cell differentiation)|go:""GO:0060948""(cardiac vascular smooth muscle cell development)|go:""GO:0060956""(endocardial cell differentiation)|go:""GO:0060979""(vasculogenesis involved in coronary vascular morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061101""(neuroendocrine cell differentiation)|go:""GO:0061344""(regulation of cell adhesion involved in heart morphogenesis)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0062043""(positive regulation of cardiac epithelial to mesenchymal transition)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0071372""(cellular response to follicle-stimulating hormone stimulus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072017""(distal tubule development)|go:""GO:0072044""(collecting duct development)|go:""GO:0072091""(regulation of stem cell proliferation)|go:""GO:0072144""(glomerular mesangial cell development)|go:""GO:0072148""(epithelial cell fate commitment)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0097400""(interleukin-17-mediated signaling pathway)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099565""(chemical synaptic transmission, postsynaptic)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:1901201""(regulation of extracellular matrix assembly)|go:""GO:1902263""(apoptotic process involved in embryonic digit morphogenesis)|go:""GO:1902339""(positive regulation of apoptotic process involved in morphogenesis)|go:""GO:1903849""(positive regulation of aorta morphogenesis)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2000974""(negative regulation of pro-B cell differentiation)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|rcsb pdb:1PB5|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:P46531|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|rcsb pdb:8OR5|rcsb pdb:8ORY|rcsb pdb:8ORZ|rcsb pdb:9B3G|rcsb pdb:9B3N|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|reactome:R-HSA-9818030|reactome:R-HSA-9818749|reactome:R-HSA-9824272|refseq:NP_060087.3|dip:DIP-29919N|efo:""Orphanet:402075""|efo:""Orphanet:974""|panther:PTHR45836(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:HyjrywO1mfKosC2W72qtvq9hL6w632	rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606	intact-crc:4CDA1AE4E9B804D2|rigid:OhwWscpyzuR2Knn8g4yW1QLRMdM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D176	uniprotkb:P46531	intact:EBI-2842041	intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587.1	psi-mi:q8d176_yerpe(display_long)|uniprotkb:y0939(locus name)	psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862574|imex:IM-13779-6771	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010158(Amidase, hydantoinase/carbamoylase)|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|go:""GO:0016813""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"")|go:""GO:0046872""(metal ion binding)|interpro:IPR036264"	"ensembl:ENSG00000148400.13(gene)|ensembl:ENST00000651671.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001554""(luteolysis)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001889""(liver development)|go:""GO:0001947""(heart looping)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0002085""(inhibition of neuroepithelial cell differentiation)|go:""GO:0002193""(MAML1-RBP-Jkappa- ICN1 complex)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003157""(endocardium development)|go:""GO:0003160""(endocardium morphogenesis)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003169""(coronary vein morphogenesis)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0003182""(coronary sinus valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003192""(mitral valve formation)|go:""GO:0003198""(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003207""(cardiac chamber formation)|go:""GO:0003208""(cardiac ventricle morphogenesis)|go:""GO:0003209""(cardiac atrium morphogenesis)|go:""GO:0003213""(cardiac right atrium morphogenesis)|go:""GO:0003214""(cardiac left ventricle morphogenesis)|go:""GO:0003219""(cardiac right ventricle formation)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003241""(growth involved in heart morphogenesis)|go:""GO:0003252""(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:""GO:0003270""(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:""GO:0003273""(cell migration involved in endocardial cushion formation)|go:""GO:0003332""(negative regulation of extracellular matrix constituent secretion)|go:""GO:0003344""(pericardium morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007221""(positive regulation of transcription of Notch receptor target)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007386""(compartment pattern specification)|go:""GO:0007411""(axon guidance)|go:""GO:0007440""(foregut morphogenesis)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009912""(auditory receptor cell fate commitment)|go:""GO:0009957""(epidermal cell fate specification)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010614""(negative regulation of cardiac muscle hypertrophy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010832""(negative regulation of myotube differentiation)|go:""GO:0014031""(mesenchymal cell development)|go:""GO:0014807""(regulation of somitogenesis)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0019899""(enzyme binding)|go:""GO:0021515""(cell differentiation in spinal cord)|go:""GO:0021915""(neural tube development)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030900""(forebrain development)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032966""(negative regulation of collagen biosynthetic process)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035148""(tube formation)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042670""(retinal cone cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045603""(positive regulation of endothelial cell differentiation)|go:""GO:0045608""(negative regulation of inner ear auditory receptor cell differentiation)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045955""(negative regulation of calcium ion-dependent exocytosis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046533""(negative regulation of photoreceptor cell differentiation)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0048103""(somatic stem cell division)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048711""(positive regulation of astrocyte differentiation)|go:""GO:0048715""(negative regulation of oligodendrocyte differentiation)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0055008""(cardiac muscle tissue morphogenesis)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060271""(cilium assembly)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0060354""(negative regulation of cell adhesion molecule production)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060528""(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:""GO:0060740""(prostate gland epithelium morphogenesis)|go:""GO:0060768""(regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:0060842""(arterial endothelial cell differentiation)|go:""GO:0060843""(venous endothelial cell differentiation)|go:""GO:0060948""(cardiac vascular smooth muscle cell development)|go:""GO:0060956""(endocardial cell differentiation)|go:""GO:0060979""(vasculogenesis involved in coronary vascular morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061101""(neuroendocrine cell differentiation)|go:""GO:0061344""(regulation of cell adhesion involved in heart morphogenesis)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0062043""(positive regulation of cardiac epithelial to mesenchymal transition)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0071372""(cellular response to follicle-stimulating hormone stimulus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072017""(distal tubule development)|go:""GO:0072044""(collecting duct development)|go:""GO:0072091""(regulation of stem cell proliferation)|go:""GO:0072144""(glomerular mesangial cell development)|go:""GO:0072148""(epithelial cell fate commitment)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0097400""(interleukin-17-mediated signaling pathway)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099565""(chemical synaptic transmission, postsynaptic)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:1901201""(regulation of extracellular matrix assembly)|go:""GO:1902263""(apoptotic process involved in embryonic digit morphogenesis)|go:""GO:1902339""(positive regulation of apoptotic process involved in morphogenesis)|go:""GO:1903849""(positive regulation of aorta morphogenesis)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2000974""(negative regulation of pro-B cell differentiation)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|rcsb pdb:1PB5|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:P46531|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|rcsb pdb:8OR5|rcsb pdb:8ORY|rcsb pdb:8ORZ|rcsb pdb:9B3G|rcsb pdb:9B3N|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|reactome:R-HSA-9818030|reactome:R-HSA-9818749|reactome:R-HSA-9824272|refseq:NP_060087.3|dip:DIP-29919N|efo:""Orphanet:402075""|efo:""Orphanet:974""|panther:PTHR45836(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:/GOJxJQAHqgWtVu6otA2a4TvHfI632	rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606	intact-crc:7A0FBB4A3615FB61|rigid:v5RWyalHvR368GRHkxJREazmivs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJJ7	uniprotkb:P46531	intact:EBI-2842396|uniprotkb:Q0WKJ5	intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587.1	psi-mi:rraa_yerpe(display_long)|uniprotkb:rraA(gene name)|psi-mi:rraA(display_short)|uniprotkb:menG(gene name synonym)|uniprotkb:YPO0103(locus name)|uniprotkb:y0292(locus name)|uniprotkb:YP_0105(locus name)	psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862567|imex:IM-13779-6768	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005493(Ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase)|interpro:IPR014339(Ribonuclease E inhibitor RraA, gammaproteobacteria)|interpro:IPR010203(Ribonuclease E inhibitor RraA)|go:""GO:0005829""(cytosol)|go:""GO:0019899""(enzyme binding)|go:""GO:0060698""(endoribonuclease inhibitor activity)|go:""GO:1902369""(negative regulation of RNA catabolic process)|refseq:WP_002208945.1|interpro:IPR036704|refseq:YP_002345193.1|panther:PTHR33254(orthology-group)"	"ensembl:ENSG00000148400.13(gene)|ensembl:ENST00000651671.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001554""(luteolysis)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001889""(liver development)|go:""GO:0001947""(heart looping)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0002085""(inhibition of neuroepithelial cell differentiation)|go:""GO:0002193""(MAML1-RBP-Jkappa- ICN1 complex)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003157""(endocardium development)|go:""GO:0003160""(endocardium morphogenesis)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003169""(coronary vein morphogenesis)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0003182""(coronary sinus valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003192""(mitral valve formation)|go:""GO:0003198""(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003207""(cardiac chamber formation)|go:""GO:0003208""(cardiac ventricle morphogenesis)|go:""GO:0003209""(cardiac atrium morphogenesis)|go:""GO:0003213""(cardiac right atrium morphogenesis)|go:""GO:0003214""(cardiac left ventricle morphogenesis)|go:""GO:0003219""(cardiac right ventricle formation)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003241""(growth involved in heart morphogenesis)|go:""GO:0003252""(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:""GO:0003270""(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:""GO:0003273""(cell migration involved in endocardial cushion formation)|go:""GO:0003332""(negative regulation of extracellular matrix constituent secretion)|go:""GO:0003344""(pericardium morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007221""(positive regulation of transcription of Notch receptor target)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007386""(compartment pattern specification)|go:""GO:0007411""(axon guidance)|go:""GO:0007440""(foregut morphogenesis)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009912""(auditory receptor cell fate commitment)|go:""GO:0009957""(epidermal cell fate specification)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010614""(negative regulation of cardiac muscle hypertrophy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010832""(negative regulation of myotube differentiation)|go:""GO:0014031""(mesenchymal cell development)|go:""GO:0014807""(regulation of somitogenesis)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0019899""(enzyme binding)|go:""GO:0021515""(cell differentiation in spinal cord)|go:""GO:0021915""(neural tube development)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030900""(forebrain development)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032966""(negative regulation of collagen biosynthetic process)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035148""(tube formation)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042670""(retinal cone cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045603""(positive regulation of endothelial cell differentiation)|go:""GO:0045608""(negative regulation of inner ear auditory receptor cell differentiation)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045955""(negative regulation of calcium ion-dependent exocytosis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046533""(negative regulation of photoreceptor cell differentiation)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0048103""(somatic stem cell division)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048711""(positive regulation of astrocyte differentiation)|go:""GO:0048715""(negative regulation of oligodendrocyte differentiation)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0055008""(cardiac muscle tissue morphogenesis)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060271""(cilium assembly)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0060354""(negative regulation of cell adhesion molecule production)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060528""(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:""GO:0060740""(prostate gland epithelium morphogenesis)|go:""GO:0060768""(regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:0060842""(arterial endothelial cell differentiation)|go:""GO:0060843""(venous endothelial cell differentiation)|go:""GO:0060948""(cardiac vascular smooth muscle cell development)|go:""GO:0060956""(endocardial cell differentiation)|go:""GO:0060979""(vasculogenesis involved in coronary vascular morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061101""(neuroendocrine cell differentiation)|go:""GO:0061344""(regulation of cell adhesion involved in heart morphogenesis)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0062043""(positive regulation of cardiac epithelial to mesenchymal transition)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0071372""(cellular response to follicle-stimulating hormone stimulus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072017""(distal tubule development)|go:""GO:0072044""(collecting duct development)|go:""GO:0072091""(regulation of stem cell proliferation)|go:""GO:0072144""(glomerular mesangial cell development)|go:""GO:0072148""(epithelial cell fate commitment)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0097400""(interleukin-17-mediated signaling pathway)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099565""(chemical synaptic transmission, postsynaptic)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:1901201""(regulation of extracellular matrix assembly)|go:""GO:1902263""(apoptotic process involved in embryonic digit morphogenesis)|go:""GO:1902339""(positive regulation of apoptotic process involved in morphogenesis)|go:""GO:1903849""(positive regulation of aorta morphogenesis)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2000974""(negative regulation of pro-B cell differentiation)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|rcsb pdb:1PB5|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:P46531|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|rcsb pdb:8OR5|rcsb pdb:8ORY|rcsb pdb:8ORZ|rcsb pdb:9B3G|rcsb pdb:9B3N|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|reactome:R-HSA-9818030|reactome:R-HSA-9818749|reactome:R-HSA-9824272|refseq:NP_060087.3|dip:DIP-29919N|efo:""Orphanet:402075""|efo:""Orphanet:974""|panther:PTHR45836(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:x8Fy09KliIuc6AQIzPt6slnvUic632	rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606	intact-crc:DF0C03F436582C3C|rigid:OsMd7UeG8o62/Z6vpWFixBPIjfk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q04721	uniprotkb:Q0WGN5	intact:EBI-2652733|uniprotkb:Q5T3X7|uniprotkb:Q99734|uniprotkb:Q9H240|ensembl:ENSP00000256646.2	intact:EBI-2842899|uniprotkb:Q74V93|uniprotkb:A0A0H2W4I5|uniprotkb:Q7CHR9|uniprotkb:A0A2U2GZQ6|uniprotkb:A0A384LHP6	psi-mi:notc2_human(display_long)|uniprotkb:NOTCH2(gene name)|psi-mi:NOTCH2(display_short)	psi-mi:q0wgn5_yerpe(display_long)|uniprotkb:YPO1537(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862560|imex:IM-13779-6772	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:261629""|efo:""Orphanet:955""|ensembl:ENSG00000134250.21(gene)|ensembl:ENST00000256646.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001709""(cell fate determination)|go:""GO:0001947""(heart looping)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0002315""(marginal zone B cell differentiation)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005929""(cilium)|go:""GO:0006915""(apoptotic process)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0007411""(axon guidance)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009986""(cell surface)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010838""(positive regulation of keratinocyte proliferation)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035622""(intrahepatic bile duct development)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042060""(wound healing)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0043011""(myeloid dendritic cell differentiation)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0046849""(bone remodeling)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0060413""(atrial septum morphogenesis)|go:""GO:0060674""(placenta blood vessel development)|go:""GO:0061073""(ciliary body morphogenesis)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0072014""(proximal tubule development)|go:""GO:0072015""(podocyte development)|go:""GO:0072104""(glomerular capillary formation)|go:""GO:0072574""(hepatocyte proliferation)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1990705""(cholangiocyte proliferation)|go:""GO:2001204""(regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022336|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:Q04721|rcsb pdb:2OO4|rcsb pdb:5MWB|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-2197563|reactome:R-HSA-2979096|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013695|refseq:NP_001186930.1|refseq:NP_077719.2|ensembl:ENSP00000256646.2|panther:PTHR45836(orthology-group)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|refseq:WP_002211883.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002346553.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aXdQSGMwNJ7K0tA2kc3rRFysbIc9606	rogid:6vMXlMR4jC89mZ3Q50YtsXLT528632	intact-crc:50B39CE00F6B644F|rigid:DSFJXTuSiHQeZSGu6+8Qf2XKFXM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H6W3	uniprotkb:A0A5P8YDU7	intact:EBI-2513645|uniprotkb:B4DT02|ensembl:ENSP00000477507.1	intact:EBI-2846054|uniprotkb:Q74VN3|uniprotkb:A0A0H2W386|uniprotkb:Q7CHG5|uniprotkb:A0A2U2H0F8|uniprotkb:A0A384KD64	psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym)	psi-mi:a0a5p8ydu7_yerpe(display_long)|uniprotkb:YPO1330(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862622|imex:IM-13779-6775	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000170468.8(gene)|ensembl:ENST00000304061.8(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0016706""(2-oxoglutarate-dependent dioxygenase activity)|go:""GO:0032453""(histone H3K4 demethylase activity)|go:""GO:0034647""(histone H3K4me/H3K4me2/H3K4me3 demethylase activity)|go:""GO:0036139""(peptidyl-histidine dioxygenase activity)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0051864""(histone H3K36 demethylase activity)|go:""GO:0140457""(protein demethylase activity)|go:""GO:0140680""(histone H3K36me/H3K36me2 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR039994|interpro:IPR049043|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y3O|rcsb pdb:4Y4R|reactome:R-HSA-9629569|refseq:NP_078920.2|dip:DIP-53768N|panther:PTHR13096(orthology-group)"	interpro:IPR019660|refseq:WP_002208763.1|refseq:YP_002346355.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RsTFUH3upRu11eleWymp6N7cEpM9606	rogid:Ue8A5mhje57pQqJVwmBF+iP8ruI632	intact-crc:663CFE06BA5B9B8F|rigid:j2RiEnfOh6gjRjSW6Dw27qDg9rU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15233	uniprotkb:Q8D0D4	intact:EBI-350527|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3|ensembl:ENSP00000276079.8|ensembl:ENSP00000362947.1|ensembl:ENSP00000406673.2|ensembl:ENSP00000410299.2|ensembl:ENSP00000415777.2|ensembl:ENSP00000503031.1|ensembl:ENSP00000503233.1|ensembl:ENSP00000504314.1|ensembl:ENSP00000504351.1	intact:EBI-2847212	psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym)	psi-mi:q8d0d4_yerpe(display_long)|uniprotkb:hmsH(gene name)|psi-mi:hmsH(display_short)|uniprotkb:y2359(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862602|imex:IM-13779-6776	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:319308""|efo:""Orphanet:466791""|ensembl:ENSG00000147140.17(gene)|ensembl:ENST00000276079.13(transcript)|ensembl:ENST00000373841.5(transcript)|ensembl:ENST00000420903.6(transcript)|ensembl:ENST00000450092.6(transcript)|ensembl:ENST00000454976.2(transcript)|ensembl:ENST00000677274.1(transcript)|ensembl:ENST00000677446.1(transcript)|ensembl:ENST00000677612.1(transcript)|ensembl:ENST00000678231.1(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0042382""(paraspeckles)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903377""(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|rcsb pdb:7PU5|refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|dip:DIP-29951N|panther:PTHR23189(orthology-group)"	"interpro:IPR023870|interpro:IPR011990(Tetratricopeptide-like helical)|go:""GO:1901515""(poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity)|interpro:IPR049003"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606	rogid:oBs/IRM9/gKecuXNw9IoCZLu4Vw632	intact-crc:063C2B11A49C340E|rigid:NHhlLLkOuGhWJ7IDZF1IfGWD+ds	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UMY1	uniprotkb:Q8CLD1	intact:EBI-2862609|uniprotkb:Q9Y3U7|uniprotkb:Q5T297|ensembl:ENSP00000405674.2	intact:EBI-2850229	psi-mi:utp16_human(display_long)|uniprotkb:NOL7(gene name)|psi-mi:NOL7(display_short)|uniprotkb:C6orf90(gene name synonym)|uniprotkb:NOP27(gene name synonym)|uniprotkb:Nucleolar protein of 27 kDa(gene name synonym)|uniprotkb:Nucleolar protein 7(gene name synonym)	psi-mi:q8cld1_yerpe(display_long)|uniprotkb:y1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862615|imex:IM-13779-6774	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057251.2|refseq:NP_001304653.1|ensembl:ENSG00000225921.7(gene)|ensembl:ENST00000451315.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0030490""(maturation of SSU-rRNA)|go:""GO:0032040""(small-subunit processome)|go:""GO:0042274""(ribosomal small subunit biogenesis)|interpro:IPR012579(NUC129)|mint:Q9UMY1|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|panther:PTHR32337(orthology-group)"	"interpro:IPR048389|interpro:IPR018702|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4I1C2wd0qGg9CWZDodm/Bp+tptA9606	rogid:kAuAUTBNF97Gsz+tSnt2gelvuPs632	intact-crc:545FD681041ED0A1|rigid:rzSMPgPRX5OnAuw5bqJVTH9AvBA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9F287	uniprotkb:Q16517	intact:EBI-2854744|uniprotkb:Q7CGE2|uniprotkb:A0A384KA49|uniprotkb:A0A1U8QHS7|uniprotkb:A0A454XLL2	intact:EBI-2862629|uniprotkb:B2R558|uniprotkb:Q16596|uniprotkb:Q5U0N3|uniprotkb:E1P5V6|ensembl:ENSP00000497164.1	psi-mi:q9f287_yerpe(display_long)|uniprotkb:yapF(gene name)|psi-mi:yapF(display_short)|uniprotkb:YPO0606(locus name)	psi-mi:nnat_human(display_long)|uniprotkb:NNAT(gene name)|psi-mi:NNAT(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862636|imex:IM-13779-6777	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR005546(Autotransporter beta-domain)|refseq:WP_002210389.1|interpro:IPR036709|refseq:YP_002345675.1	"refseq:NP_005377.1|refseq:NP_859017.1|refseq:NP_001309731.1|ensembl:ENSG00000053438.11(gene)|ensembl:ENST00000649451.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0007420""(brain development)|go:""GO:0009249""(protein lipoylation)|go:""GO:0032024""(positive regulation of insulin secretion)|interpro:IPR024885|panther:PTHR15285(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uIQ9881A2N1D063pjSQtEbbJqNs632	rogid:hXkhbzr8F2FpsnX+iVuSFuJQsD89606	intact-crc:1950DBE3FE19A71F|rigid:CVs4D0E+lkOPSagSwBH8U4CLHH8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJI2	uniprotkb:P46531	intact:EBI-2851979|uniprotkb:Q0WKH7	intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587.1	psi-mi:malt_yerpe(display_long)|uniprotkb:malT(gene name)|psi-mi:malT(display_short)|uniprotkb:ATP-dependent transcriptional activator MalT(gene name synonym)|uniprotkb:YPO0123(locus name)|uniprotkb:YP_0125(locus name)|uniprotkb:y3900(locus name)	psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862595|imex:IM-13779-6773	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023768|interpro:IPR000792(Bacterial regulatory protein, LuxR)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045913""(positive regulation of carbohydrate metabolic process)|interpro:IPR036388|refseq:WP_002208926.1|refseq:YP_002345211.1|panther:PTHR44688(orthology-group)"	"ensembl:ENSG00000148400.13(gene)|ensembl:ENST00000651671.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001554""(luteolysis)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001889""(liver development)|go:""GO:0001947""(heart looping)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0002085""(inhibition of neuroepithelial cell differentiation)|go:""GO:0002193""(MAML1-RBP-Jkappa- ICN1 complex)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003157""(endocardium development)|go:""GO:0003160""(endocardium morphogenesis)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003169""(coronary vein morphogenesis)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0003182""(coronary sinus valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003192""(mitral valve formation)|go:""GO:0003198""(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003207""(cardiac chamber formation)|go:""GO:0003208""(cardiac ventricle morphogenesis)|go:""GO:0003209""(cardiac atrium morphogenesis)|go:""GO:0003213""(cardiac right atrium morphogenesis)|go:""GO:0003214""(cardiac left ventricle morphogenesis)|go:""GO:0003219""(cardiac right ventricle formation)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003241""(growth involved in heart morphogenesis)|go:""GO:0003252""(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:""GO:0003270""(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:""GO:0003273""(cell migration involved in endocardial cushion formation)|go:""GO:0003332""(negative regulation of extracellular matrix constituent secretion)|go:""GO:0003344""(pericardium morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007221""(positive regulation of transcription of Notch receptor target)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007386""(compartment pattern specification)|go:""GO:0007411""(axon guidance)|go:""GO:0007440""(foregut morphogenesis)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009912""(auditory receptor cell fate commitment)|go:""GO:0009957""(epidermal cell fate specification)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010614""(negative regulation of cardiac muscle hypertrophy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010832""(negative regulation of myotube differentiation)|go:""GO:0014031""(mesenchymal cell development)|go:""GO:0014807""(regulation of somitogenesis)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0019899""(enzyme binding)|go:""GO:0021515""(cell differentiation in spinal cord)|go:""GO:0021915""(neural tube development)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030900""(forebrain development)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032966""(negative regulation of collagen biosynthetic process)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035148""(tube formation)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042670""(retinal cone cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045603""(positive regulation of endothelial cell differentiation)|go:""GO:0045608""(negative regulation of inner ear auditory receptor cell differentiation)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045955""(negative regulation of calcium ion-dependent exocytosis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046533""(negative regulation of photoreceptor cell differentiation)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0048103""(somatic stem cell division)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048711""(positive regulation of astrocyte differentiation)|go:""GO:0048715""(negative regulation of oligodendrocyte differentiation)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0055008""(cardiac muscle tissue morphogenesis)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060271""(cilium assembly)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0060354""(negative regulation of cell adhesion molecule production)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060528""(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:""GO:0060740""(prostate gland epithelium morphogenesis)|go:""GO:0060768""(regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:0060842""(arterial endothelial cell differentiation)|go:""GO:0060843""(venous endothelial cell differentiation)|go:""GO:0060948""(cardiac vascular smooth muscle cell development)|go:""GO:0060956""(endocardial cell differentiation)|go:""GO:0060979""(vasculogenesis involved in coronary vascular morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061101""(neuroendocrine cell differentiation)|go:""GO:0061344""(regulation of cell adhesion involved in heart morphogenesis)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0062043""(positive regulation of cardiac epithelial to mesenchymal transition)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0071372""(cellular response to follicle-stimulating hormone stimulus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072017""(distal tubule development)|go:""GO:0072044""(collecting duct development)|go:""GO:0072091""(regulation of stem cell proliferation)|go:""GO:0072144""(glomerular mesangial cell development)|go:""GO:0072148""(epithelial cell fate commitment)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0097400""(interleukin-17-mediated signaling pathway)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099565""(chemical synaptic transmission, postsynaptic)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:1901201""(regulation of extracellular matrix assembly)|go:""GO:1902263""(apoptotic process involved in embryonic digit morphogenesis)|go:""GO:1902339""(positive regulation of apoptotic process involved in morphogenesis)|go:""GO:1903849""(positive regulation of aorta morphogenesis)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2000974""(negative regulation of pro-B cell differentiation)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|rcsb pdb:1PB5|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:P46531|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|rcsb pdb:8OR5|rcsb pdb:8ORY|rcsb pdb:8ORZ|rcsb pdb:9B3G|rcsb pdb:9B3N|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|reactome:R-HSA-9818030|reactome:R-HSA-9818749|reactome:R-HSA-9824272|refseq:NP_060087.3|dip:DIP-29919N|efo:""Orphanet:402075""|efo:""Orphanet:974""|panther:PTHR45836(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:pwBOx98oeu/gM/SCtiq2SiDs4nE632	rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606	intact-crc:FD9F03F43777CBA1|rigid:ZbXhX+MSCSP9RnfpV6INANxuacI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLT3	uniprotkb:Q9HBL8	intact:EBI-2845884	intact:EBI-2862643|ensembl:ENSP00000283429.6|ensembl:ENSP00000383962.3|ensembl:ENSP00000458762.1|ensembl:ENSP00000460263.1|ensembl:ENSP00000478990.1|ensembl:ENSP00000479569.1|ensembl:ENSP00000488644.1|ensembl:ENSP00000488692.1	psi-mi:q8clt3_yerpe(display_long)|uniprotkb:y0272(locus name)	psi-mi:nmrl1_human(display_long)|uniprotkb:NMRAL1(gene name)|psi-mi:NMRAL1(display_short)|uniprotkb:HSCARG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862647|imex:IM-13779-6780	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010657(ImpA, N-terminal)|interpro:IPR017739(Type VI secretion system-associated, VCA0119)	"refseq:NP_001292070.1|refseq:NP_001292071.1|refseq:NP_065728.1|dip:DIP-60944N|ensembl:ENSG00000153406.14(gene)|ensembl:ENSG00000274684.4(gene)|ensembl:ENST00000283429.11(transcript)|ensembl:ENST00000404295.7(transcript)|ensembl:ENST00000574425.5(transcript)|ensembl:ENST00000574733.5(transcript)|ensembl:ENST00000616587.2(transcript)|ensembl:ENST00000621810.4(transcript)|ensembl:ENST00000632013.1(transcript)|ensembl:ENST00000633085.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR008030(NmrA-like)|interpro:IPR036291|interpro:IPR051164|rcsb pdb:2EXX|rcsb pdb:2WM3|rcsb pdb:2WMD|rcsb pdb:3DXF|rcsb pdb:3E5M|reactome:R-HSA-70635|panther:PTHR42748(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6TnQPOOe3FeEE1LWQVyzY/Oug6E632	rogid:9q42cK1M0HrGZy3OG82g1RQ9sOo9606	intact-crc:5E0C1045BA9CA035|rigid:kYPgGaKfpGHxMGvlLc9bpmCY8FA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG0	uniprotkb:Q9HBL8	intact:EBI-2842527|uniprotkb:Q8CKL4|uniprotkb:Q0WIA2|uniprotkb:Q74QH2	intact:EBI-2862643|ensembl:ENSP00000283429.6|ensembl:ENSP00000383962.3|ensembl:ENSP00000458762.1|ensembl:ENSP00000460263.1|ensembl:ENSP00000478990.1|ensembl:ENSP00000479569.1|ensembl:ENSP00000488644.1|ensembl:ENSP00000488692.1	psi-mi:agua_yerpe(display_long)|uniprotkb:aguA(gene name)|psi-mi:aguA(display_short)|uniprotkb:Agmatine iminohydrolase(gene name synonym)|uniprotkb:YPO0939(locus name)|uniprotkb:y3325(locus name)|uniprotkb:YP_3503(locus name)	psi-mi:nmrl1_human(display_long)|uniprotkb:NMRAL1(gene name)|psi-mi:NMRAL1(display_short)|uniprotkb:HSCARG(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862654|imex:IM-13779-6778	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017754(Agmatine deiminase)|interpro:IPR007466(Peptidyl-arginine deiminase, Porphyromonas-type)|go:""GO:0004668""(protein-arginine deiminase activity)|go:""GO:0009446""(putrescine biosynthetic process)|go:""GO:0047632""(agmatine deiminase activity)|refseq:YP_002345986.1|panther:PTHR31377(orthology-group)"	"refseq:NP_001292070.1|refseq:NP_001292071.1|refseq:NP_065728.1|dip:DIP-60944N|ensembl:ENSG00000153406.14(gene)|ensembl:ENSG00000274684.4(gene)|ensembl:ENST00000283429.11(transcript)|ensembl:ENST00000404295.7(transcript)|ensembl:ENST00000574425.5(transcript)|ensembl:ENST00000574733.5(transcript)|ensembl:ENST00000616587.2(transcript)|ensembl:ENST00000621810.4(transcript)|ensembl:ENST00000632013.1(transcript)|ensembl:ENST00000633085.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR008030(NmrA-like)|interpro:IPR036291|interpro:IPR051164|rcsb pdb:2EXX|rcsb pdb:2WM3|rcsb pdb:2WMD|rcsb pdb:3DXF|rcsb pdb:3E5M|reactome:R-HSA-70635|panther:PTHR42748(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wqVmguxc+OwAcDUbyMd1UcCWH/o632	rogid:9q42cK1M0HrGZy3OG82g1RQ9sOo9606	intact-crc:59A135ACBA7C8A3C|rigid:3n7fnRQccTeOmis15dbTpnf352U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GXR2	uniprotkb:Q13287	intact:EBI-2843146|uniprotkb:Q74PJ2|uniprotkb:Q0WB19|uniprotkb:Q7CL49|uniprotkb:A0A3N4AWB6|uniprotkb:A0A384LGR5	intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|ensembl:ENSP00000243346.5|uniprotkb:B5BU69	psi-mi:a0a2u2gxr2_yerpe(display_long)|uniprotkb:YPO3634(locus name)	psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862673|imex:IM-13779-6781	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002210044.1|refseq:YP_002348519.1|interpro:IPR050107"	"ensembl:ENSG00000123609.11(gene)|ensembl:ENST00000243346.10(transcript)|go:""GO:0002281""(macrophage activation involved in immune response)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0032687""(negative regulation of interferon-alpha production)|go:""GO:0032688""(negative regulation of interferon-beta production)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902524""(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q13287|reactome:R-HSA-9692916|refseq:NP_004679.2|refseq:XP_005246998.1|refseq:XP_016860736.1|panther:PTHR15225(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:J+WSGnBdkicCNERBIkk/oDw6qcU632	rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606	intact-crc:10700EC8DCEB18A7|rigid:hW5ZRrxQHILuWfCZVYL4Jxqictw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13287	uniprotkb:Q8ZJ07	intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|ensembl:ENSP00000243346.5|uniprotkb:B5BU69	intact:EBI-2862664|uniprotkb:Q0WJY4	psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym)	psi-mi:uvra_yerpe(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:YPO0324(locus name)|uniprotkb:y0580(locus name)|uniprotkb:YP_0479(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862661|imex:IM-13779-6779	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000123609.11(gene)|ensembl:ENST00000243346.10(transcript)|go:""GO:0002281""(macrophage activation involved in immune response)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0032687""(negative regulation of interferon-alpha production)|go:""GO:0032688""(negative regulation of interferon-beta production)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902524""(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q13287|reactome:R-HSA-9692916|refseq:NP_004679.2|refseq:XP_005246998.1|refseq:XP_016860736.1|panther:PTHR15225(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|interpro:IPR027417|refseq:WP_002209099.1|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR041102|interpro:IPR041552|refseq:YP_002345404.1|interpro:IPR013815(ATP-grasp fold, subdomain 1)|panther:PTHR43152(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606	rogid:3YrM2RVQkyTivw5n1TtLhIWMTlw632	intact-crc:A1E4DF88D00E9B31|rigid:mMqs7lhWQdgnzuNp+gvuLDtatpw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13287	uniprotkb:A0A3N4BEU0	intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|ensembl:ENSP00000243346.5|uniprotkb:B5BU69	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym)	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862692|imex:IM-13779-6782	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000123609.11(gene)|ensembl:ENST00000243346.10(transcript)|go:""GO:0002281""(macrophage activation involved in immune response)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0032687""(negative regulation of interferon-alpha production)|go:""GO:0032688""(negative regulation of interferon-beta production)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902524""(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q13287|reactome:R-HSA-9692916|refseq:NP_004679.2|refseq:XP_005246998.1|refseq:XP_016860736.1|panther:PTHR15225(orthology-group)"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	intact-crc:D86A9E724DFA2BA9|rigid:VtqrocMgEguCUt2vRBSX0ub+Vn0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PGI3	uniprotkb:Q13287	intact:EBI-2862680|uniprotkb:Q74XT1|uniprotkb:Q7CKD2|uniprotkb:Q0WBR6	intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|ensembl:ENSP00000243346.5|uniprotkb:B5BU69	"psi-mi:a0a380pgi3_yerpe(display_long)|uniprotkb:relA(gene name)|psi-mi:relA(display_short)|uniprotkb:""(p)ppGpp synthase""(gene name synonym)|uniprotkb:""ATP:GTP 3'-pyrophosphotransferase""(gene name synonym)|uniprotkb:ppGpp synthase I(gene name synonym)|uniprotkb:YPO3380(locus name)"	psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862685|imex:IM-13779-6786	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR007685(RelA/SpoT)|interpro:IPR004811(RelA/SpoT protein)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR033655|refseq:WP_002209373.1|go:""GO:0005525""(GTP binding)|go:""GO:0008728""(GTP diphosphokinase activity)|go:""GO:0008893""(""guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"")|go:""GO:0015969""(guanosine tetraphosphate metabolic process)|go:""GO:0016301""(kinase activity)|go:""GO:0042594""(response to starvation)|interpro:IPR043519|refseq:YP_002348272.1|interpro:IPR045600|interpro:IPR045865|panther:PTHR21262(orthology-group)"	"ensembl:ENSG00000123609.11(gene)|ensembl:ENST00000243346.10(transcript)|go:""GO:0002281""(macrophage activation involved in immune response)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0032687""(negative regulation of interferon-alpha production)|go:""GO:0032688""(negative regulation of interferon-beta production)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1901223""(negative regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1902524""(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q13287|reactome:R-HSA-9692916|refseq:NP_004679.2|refseq:XP_005246998.1|refseq:XP_016860736.1|panther:PTHR15225(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aBn/E1vqPCod/YzywGW3/zIVN3s632	rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606	intact-crc:69A52CEEFC537525|rigid:lwY+sjUUoDdykPfyBUezlcJAgQE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N0W4	uniprotkb:Q9ZC68	intact:EBI-2862707|uniprotkb:Q9ULG0|uniprotkb:Q6UX10|ensembl:ENSP00000275857.6|ensembl:ENSP00000370482.1|ensembl:ENSP00000370483.3|ensembl:ENSP00000370485.3	intact:EBI-2843867|uniprotkb:Q7CI72|uniprotkb:Q74UK4	psi-mi:nlgnx_human(display_long)|uniprotkb:NLGN4X(gene name)|psi-mi:NLGN4X(display_short)|uniprotkb:KIAA1260(gene name synonym)|uniprotkb:NLGN4(gene name synonym)|uniprotkb:HNLX(gene name synonym)|uniprotkb:UNQ365/PRO701(orf name)	psi-mi:astd_yerpe(display_long)|uniprotkb:astD(gene name)|psi-mi:astD(display_short)|uniprotkb:Succinylglutamic semialdehyde dehydrogenase(gene name synonym)|uniprotkb:YPO1964(locus name)|uniprotkb:y2347(locus name)|uniprotkb:YP_1709(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862713|imex:IM-13779-6783	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269074.1|refseq:NP_001269075.1|refseq:NP_065793.1|refseq:NP_851849.1|refseq:XP_005274621.1|refseq:XP_005274622.1|refseq:XP_005274623.1|refseq:XP_006724567.1|refseq:XP_011543849.1|refseq:XP_011543850.1|refseq:XP_016885179.1|refseq:XP_016885180.1|refseq:XP_016885181.1|refseq:XP_016885182.1|ensembl:ENSG00000146938.16(gene)|ensembl:ENST00000275857.10(transcript)|ensembl:ENST00000381092.1(transcript)|ensembl:ENST00000381093.6(transcript)|ensembl:ENST00000381095.8(transcript)|go:""GO:0003360""(brainstem development)|go:""GO:0005886""(plasma membrane)|go:""GO:0007158""(neuron cell-cell adhesion)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007612""(learning)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0021549""(cerebellum development)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030425""(dendrite)|go:""GO:0030534""(adult behavior)|go:""GO:0031404""(chloride ion binding)|go:""GO:0035176""(social behavior)|go:""GO:0035265""(organ growth)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042043""(neurexin family protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045202""(synapse)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050808""(synapse organization)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051963""(regulation of synapse assembly)|go:""GO:0060076""(excitatory synapse)|go:""GO:0071625""(vocalization behavior)|go:""GO:0090394""(negative regulation of excitatory postsynaptic potential)|go:""GO:0097104""(postsynaptic membrane assembly)|go:""GO:0097105""(presynaptic membrane assembly)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098793""(presynapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0098983""(symmetric, GABA-ergic, inhibitory synapse)|go:""GO:0098985""(asymmetric, glutamatergic, excitatory synapse)|go:""GO:0099054""(presynapse assembly)|go:""GO:0099634""(postsynaptic specialization membrane)|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR029058|interpro:IPR051093|mint:Q8N0W4|rcsb pdb:2WQZ|rcsb pdb:2XB6|rcsb pdb:3BE8|reactome:R-HSA-6794361|panther:PTHR43903(orthology-group)"	"refseq:WP_002212030.1|interpro:IPR029510|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR017649(Succinylglutamic semialdehyde dehydrogenase)|go:""GO:0019544""(arginine catabolic process to glutamate)|go:""GO:0019545""(arginine catabolic process to succinate)|go:""GO:0043824""(succinylglutamate-semialdehyde dehydrogenase activity)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:YP_002346953.1|panther:PTHR11699(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7PtRrX28usbCkTHxS8QfWEgDEn49606	rogid:lAw8pbIH2i1IjXZl8H7zAJvQj0I632	intact-crc:3DD6AC031C9CB358|rigid:mjpnq0GI8aipCBD1Q9u4IH9qIHM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PM60	uniprotkb:P30414	intact:EBI-2853592|uniprotkb:Q74TV9|uniprotkb:Q0WEU8|uniprotkb:Q7CIL8|uniprotkb:A0A384KHN0	intact:EBI-1642562|ensembl:ENSP00000232978.8	psi-mi:a0a2s9pm60_yerpe(display_long)|uniprotkb:supX(gene name)|psi-mi:supX(display_short)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:topA(gene name synonym)|uniprotkb:YPO2218(locus name)	psi-mi:nktr_human(display_long)|uniprotkb:NKTR(gene name)|psi-mi:NKTR(display_short)|uniprotkb:Natural-killer cells cyclophilin-related protein(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase NKTR(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862720|imex:IM-13779-6784	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023406|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR023405|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR005733(DNA topoisomerase I, bacterial-type)|interpro:IPR013263(DNA topoisomerase I, zinc ribbon-like, bacterial-type)|interpro:IPR006171(TOPRIM)|refseq:WP_002210622.1|interpro:IPR034149|go:""GO:0003677""(DNA binding)|go:""GO:0003917""(""DNA topoisomerase type I (single strand cut, ATP-independent) activity"")|go:""GO:0005694""(chromosome)|go:""GO:0006265""(DNA topological change)|go:""GO:0046872""(metal ion binding)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR049330|interpro:IPR028612|refseq:YP_002347190.1|panther:PTHR42785(orthology-group)"	"refseq:NP_005376.2|ensembl:ENSG00000114857.19(gene)|ensembl:ENST00000232978.13(transcript)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005886""(plasma membrane)|go:""GO:0006457""(protein folding)|go:""GO:0016018""(cyclosporin A binding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P30414|rcsb pdb:2HE9"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sBCN9yVi7vZQU8tykRnvKWsTra8632	rogid:+klgWL+1/tJS3kNQb6HDqh7n4FY9606	intact-crc:7318604D95E32AC6|rigid:7hI7KrhaUEJFTpko7zcmh30m+SM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P22307	uniprotkb:A0A2S9PKV8	intact:EBI-1050999|uniprotkb:Q15432|uniprotkb:Q16622|uniprotkb:Q99430|uniprotkb:Q5VVZ1|uniprotkb:D3DQ37|uniprotkb:Q6NXF4|uniprotkb:B4DHP6|uniprotkb:A6NM69|uniprotkb:B4DGJ9|uniprotkb:C9JC79|uniprotkb:E1B6W5|uniprotkb:F2Z3J1|ensembl:ENSP00000360569.3	intact:EBI-2859198|uniprotkb:Q74WD4|uniprotkb:Q0WHK6|uniprotkb:Q7CH84|uniprotkb:A0A384KBV6	psi-mi:scp2_human(display_long)|uniprotkb:Propanoyl-CoA C-acyltransferase(gene name synonym)|uniprotkb:Sterol carrier protein X(gene name synonym)|uniprotkb:SCP-chi(gene name synonym)|uniprotkb:SCPX(gene name synonym)|uniprotkb:SCP2(gene name)|psi-mi:SCP2(display_short)|uniprotkb:Acetyl-CoA C-myristoyltransferase(gene name synonym)|uniprotkb:Non-specific lipid-transfer protein(gene name synonym)|uniprotkb:SCP-2/3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:SCP-2/thiolase(gene name synonym)	psi-mi:a0a2s9pkv8_yerpe(display_long)|uniprotkb:YPO1194(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862699|imex:IM-13779-6785	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:163684""|ensembl:ENSG00000116171.19(gene)|ensembl:ENST00000371514.8(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0003988""(acetyl-CoA C-acyltransferase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0006694""(steroid biosynthetic process)|go:""GO:0006699""(bile acid biosynthetic process)|go:""GO:0006701""(progesterone biosynthetic process)|go:""GO:0008206""(bile acid metabolic process)|go:""GO:0008526""(phosphatidylinositol transfer activity)|go:""GO:0015485""(cholesterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0016020""(membrane)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0032385""(positive regulation of intracellular cholesterol transport)|go:""GO:0032959""(inositol trisphosphate biosynthetic process)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033540""(fatty acid beta-oxidation using acyl-CoA oxidase)|go:""GO:0033814""(propanoyl-CoA C-acyltransferase activity)|go:""GO:0036042""(long-chain fatty acyl-CoA binding)|go:""GO:0036109""(alpha-linolenic acid metabolic process)|go:""GO:0045940""(positive regulation of steroid metabolic process)|go:""GO:0050632""(propionyl-CoA C2-trimethyltridecanoyltransferase activity)|go:""GO:0050633""(acetyl-CoA C-myristoyltransferase activity)|go:""GO:0070538""(oleic acid binding)|go:""GO:0071071""(regulation of phospholipid biosynthetic process)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0120019""(phosphatidylcholine transfer activity)|go:""GO:0120020""(cholesterol transfer activity)|go:""GO:1901373""(lipid hydroperoxide transport)|interpro:IPR003033(Sterol-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR036527|interpro:IPR055140|mint:P22307|rcsb pdb:1QND|rcsb pdb:2C0L|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-9033241|reactome:R-HSA-9033500|refseq:NP_001007099.1|refseq:NP_001007100.1|refseq:NP_001007101.1|refseq:NP_001007251.1|refseq:NP_001180528.1|refseq:NP_001180546.1|refseq:NP_002970.2|refseq:XP_016857535.1|panther:PTHR24314(orthology-group)"	"interpro:IPR001763(Rhodanese-like)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|refseq:WP_002210799.1|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0016784""(3-mercaptopyruvate sulfurtransferase activity)|interpro:IPR036873|refseq:YP_002346232.1|interpro:IPR045078|panther:PTHR11364(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Vwnu7RuD/2qhcH55Fl9v2TMErtc9606	rogid:tC9S/oaqk3d0afXfuawLwoksqPQ632	intact-crc:4D5BE5C2EA62F0D0|rigid:qhYe3u8ucFA/DPfKzY8TUMuzIuo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75323	uniprotkb:A0A2U2H1N8	intact:EBI-307133|uniprotkb:O43801|uniprotkb:Q53X96|uniprotkb:C9IYJ3|ensembl:ENSP00000313050.3	intact:EBI-2854536|uniprotkb:Q0WD60|uniprotkb:A0A5P8YHP9|uniprotkb:Q7CJK5|uniprotkb:A0A384KNX2	psi-mi:nips2_human(display_long)|uniprotkb:NIPSNAP2(gene name)|psi-mi:NIPSNAP2(display_short)|uniprotkb:GBAS(gene name synonym)|uniprotkb:Glioblastoma-amplified sequence(gene name synonym)	psi-mi:a0a2u2h1n8_yerpe(display_long)|uniprotkb:YPO2840(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862741|imex:IM-13779-6790	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001189398.1|refseq:NP_001474.1|ensembl:ENSG00000146729.10(gene)|ensembl:ENST00000322090.8(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:1901843""(positive regulation of high voltage-gated calcium channel activity)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|interpro:IPR051557|mint:O75323|reactome:R-HSA-9013407|reactome:R-HSA-9013409|dip:DIP-33564N|panther:PTHR21017(orthology-group)"	"interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|refseq:WP_002209785.1|go:""GO:0005524""(ATP binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR043129|interpro:IPR042054|refseq:YP_002347778.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:sfBQGdtSVoH21kBu/Bz9x8x3KWU9606	rogid:DJFhATcAkt0yMS26gohYZy89ip4632	intact-crc:45D9A75510371575|rigid:9ij66KaQFvd3dQPy9AksycRZAeU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZF9	uniprotkb:Q9UJF2	intact:EBI-2845517	intact:EBI-359444|uniprotkb:O95174|uniprotkb:Q5TFU9|uniprotkb:F8W755|uniprotkb:Q2TB22|ensembl:ENSP00000420558.1	psi-mi:q8czf9_yerpe(display_long)|uniprotkb:y4123(locus name)	psi-mi:ngap_human(display_long)|uniprotkb:RASAL2(gene name)|psi-mi:RASAL2(display_short)|uniprotkb:NGAP(gene name synonym)|uniprotkb:RAS protein activator-like 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862757|imex:IM-13779-6789	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|interpro:IPR035906|interpro:IPR043429"	"refseq:NP_004832.1|refseq:NP_733793.2|ensembl:ENSG00000075391.18(gene)|ensembl:ENST00000462775.5(transcript)|go:""GO:0002021""(response to dietary excess)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0009749""(response to glucose)|go:""GO:0010467""(gene expression)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0060612""(adipose tissue development)|go:""GO:2000257""(regulation of protein activation cascade)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR039360|mint:Q9UJF2|reactome:R-HSA-5658442|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-27570N|panther:PTHR10194(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lTT/EDwWVuu+Fb2mxQH/pcMBusE632	rogid:nWiB+5VCXMzJXDsyu5G5QkhyQV49606	intact-crc:1BB843006C479449|rigid:r80aYjwElofjlcEMxnhS4MMi+84	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P69970	uniprotkb:P19838	intact:EBI-2862764|uniprotkb:Q663I1|uniprotkb:Q00933	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:ysci_yerpe(display_long)|uniprotkb:yscI(gene name)|psi-mi:yscI(display_short)|uniprotkb:lcrO(gene name synonym)|uniprotkb:Low calcium response locus protein O(gene name synonym)|uniprotkb:YPCD1.58(locus name)|uniprotkb:y5020(locus name)|uniprotkb:y0023(locus name)|uniprotkb:YP_pCD25(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862770|imex:IM-13779-6791	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012670(Type III secretion system YscI/HrpB)|refseq:NP_395192.1|refseq:NP_857724.1|refseq:NP_857919.1|mint:P69970|refseq:WP_002212914.1|go:""GO:0030254""(protein secretion by the type III secretion system)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:9PW6IwgfB1tJdJQ+NpneS6g3hHg632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:C6AFB57C0B6740B4|rigid:U/rqSvheu3mV10BFzsMD5WYfaCQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14543	uniprotkb:Q8ZD36	intact:EBI-2828729|uniprotkb:Q86XD7|uniprotkb:Q5TAF3|uniprotkb:Q5TAF2|uniprotkb:Q14942|uniprotkb:Q59FL2|ensembl:ENSP00000264187.6	intact:EBI-2853182|uniprotkb:Q0WDD5|intact:EBI-2862751	psi-mi:nid1_human(display_long)|uniprotkb:NID1(gene name)|psi-mi:NID1(display_short)|uniprotkb:NID(gene name synonym)|uniprotkb:Entactin(gene name synonym)	psi-mi:mnmc_yerpe(display_long)|uniprotkb:mnmC(gene name)|psi-mi:mnmC(display_short)|uniprotkb:YPO2756(locus name)|uniprotkb:y1590(locus name)|uniprotkb:YP_2407(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862748|imex:IM-13779-6788	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:269215""|ensembl:ENSG00000116962.15(gene)|ensembl:ENST00000264187.7(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0032836""(glomerular basement membrane development)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0043236""(laminin binding)|go:""GO:0043237""(laminin-1 binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071711""(basement membrane organization)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:0110011""(regulation of basement membrane organization)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036857|interpro:IPR049883|interpro:IPR050778|mint:P14543|reactome:R-HSA-1474228|reactome:R-HSA-3000157|refseq:NP_002499.2|panther:PTHR46513(orthology-group)"	"interpro:IPR029063|interpro:IPR008471(Protein of unknown function DUF752)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR023032|interpro:IPR017610(tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal)|rcsb pdb:3PVC|rcsb pdb:3SGL|refseq:WP_002209716.1|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0004808""(""tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0016645""(oxidoreductase activity, acting on the CH-NH group of donors)|go:""GO:0032259""(methylation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR047785|interpro:IPR036188|refseq:YP_002347703.1|panther:PTHR13847(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xlqES3FTQirfYhb0lB7RfGpFQms9606	rogid:WUUEfp2U7AMQZl+RUxlKHTdbp3E632	intact-crc:52733028001CB57C|rigid:pOxeWus/TFRYNmFTMQ4jZZZH2TE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PJK8	uniprotkb:Q07444	intact:EBI-2842311|uniprotkb:Q0WI69|uniprotkb:Q7CGQ2	intact:EBI-2862730|uniprotkb:Q8WXA4|uniprotkb:Q96RL0|uniprotkb:Q9UP04|ensembl:ENSP00000379716.3	psi-mi:a0a380pjk8_yerpe(display_long)|uniprotkb:clpB3(gene name)|psi-mi:clpB3(display_short)|uniprotkb:YPO0971(locus name)	psi-mi:nkg2e_human(display_long)|uniprotkb:KLRC3(gene name)|psi-mi:KLRC3(display_short)|uniprotkb:NKG2E(gene name synonym)|uniprotkb:NK cell receptor E(gene name synonym)|uniprotkb:NKG2-E-activating NK receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862727|imex:IM-13779-6787	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR017729(Type VI secretion system ATPase, ClpV1)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR041546|interpro:IPR004176(Clp, N-terminal)|interpro:IPR018368|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034605""(cellular response to heat)|refseq:WP_002210013.1|interpro:IPR036628|refseq:YP_002346019.1|interpro:IPR050130|panther:PTHR11638(orthology-group)"	"refseq:NP_002252.2|refseq:NP_031359.2|ensembl:ENSG00000205810.9(gene)|ensembl:ENST00000396439.7(transcript)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006968""(cellular defense response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0032814""(regulation of natural killer cell activation)|go:""GO:0043235""(receptor complex)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR050919|panther:PTHR22800(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zRQmsquHSeoveoOQnnSmxw1Hb2s632	rogid:iBkVAcFpnbToIXegyaUH+yy0wAg9606	intact-crc:00EF4AC55B572022|rigid:WfCIXMmtXpcitEIz8JDFhnIDcWw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8ZAF1	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2847121|uniprotkb:Q0WAF4	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:wzye_yerpe(display_long)|uniprotkb:wzyE(gene name)|psi-mi:wzyE(display_short)|uniprotkb:wecF(gene name synonym)|uniprotkb:YPO3856(locus name)|uniprotkb:y0372(locus name)|uniprotkb:YP_3189(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862809|imex:IM-13779-6793	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR010691(WzyE)|go:""GO:0005886""(plasma membrane)|go:""GO:0009246""(enterobacterial common antigen biosynthetic process)|refseq:WP_002211978.1|refseq:YP_002348734.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:DunRXV3CpPUWSRQnNPV6bIM/Ao8632	intact-crc:7E444E5B7858031B|rigid:tBKHC4slQADr6Vlpt9dQsJedKsw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8ZEL2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2862801|uniprotkb:Q0WF10	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:y2152_yerpe(display_long)|uniprotkb:YPO2152(locus name)|uniprotkb:y2169(locus name)|uniprotkb:YP_1953(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862798|imex:IM-13779-6795	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	interpro:IPR006698(Protein of unknown function DUF444)|refseq:WP_002216501.1|refseq:YP_002347128.1|panther:PTHR30510(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:ltlXLZc6jWpriCSKFSImopncuEY632	intact-crc:0F5B8A5B78BF5DE6|rigid:O3q5/i9ldUitF+i3xcR1hx9Bwsc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8ZF52	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2854921|uniprotkb:Q0WFS8	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:uvrc_yerpe(display_long)|uniprotkb:uvrC(gene name)|psi-mi:uvrC(display_short)|uniprotkb:Excinuclease ABC subunit C(gene name synonym)|uniprotkb:YPO1866(locus name)|uniprotkb:y2442(locus name)|uniprotkb:YP_1527(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862816|imex:IM-13779-6794	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR050066|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004791(Excinuclease ABC, C subunit)|interpro:IPR001162(Excinuclease ABC, C subunit, C-terminal)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|refseq:WP_002220477.1|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0006974""(DNA damage response)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|interpro:IPR038476|interpro:IPR035901|interpro:IPR036876|interpro:IPR047296|panther:PTHR30562(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:2hYaQAbyVPud5UOaDjypnf1geRA632	intact-crc:4395195B78AF162E|rigid:6l+i+A8aCGnWGuKEdAQEHVS7xU4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9RI12	uniprotkb:P19838	intact:EBI-2849107|uniprotkb:O68717	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862777|imex:IM-13779-6796	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:4452FD0E09AE66A0|rigid:Uz1yxaYtbvPO8PXRjN9ki350PrY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8ZH58	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2862787|uniprotkb:Q0WHZ3|uniprotkb:Q74S49|uniprotkb:Q7CH17	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:bama_yerpe(display_long)|uniprotkb:bamA(gene name)|psi-mi:bamA(display_short)|uniprotkb:yaeT(gene name synonym)|uniprotkb:YPO1052(locus name)|uniprotkb:YP_2798(locus name)|uniprotkb:y3127(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862784|imex:IM-13779-6792	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR000184(""Bacterial surface antigen (D15)"")|interpro:IPR023707|interpro:IPR010827(Surface antigen variable number)|interpro:IPR039910|refseq:WP_002212139.1|interpro:IPR034746|go:""GO:0043165""(Gram-negative-bacterium-type cell outer membrane assembly)|go:""GO:0051205""(protein insertion into membrane)|go:""GO:1990063""(Bam protein complex)|refseq:YP_002346095.1|panther:PTHR12815(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:Xorri/Lj4IPQjfwdPW+QCtrp4m8632	intact-crc:8DB1B75B7AF1103A|rigid:xoU1XQ6vLyoZg3+PGu/2GURJcZY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIM0	uniprotkb:P19838	intact:EBI-2841754|uniprotkb:Q74Q17|uniprotkb:Q0WJJ1|uniprotkb:Q7CG80	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:syi_yerpe(display_long)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO0475(locus name)|uniprotkb:YP_3705(locus name)|uniprotkb:y3700(locus name)|uniprotkb:ileS(gene name)|psi-mi:ileS(display_short)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862823|imex:IM-13779-6797	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR023585|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR033708|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004822""(isoleucine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006428""(isoleucyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|refseq:YP_002345547.1|refseq:WP_002210509.1|interpro:IPR050081|panther:PTHR42765(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:bmNNQqKAFmtm7vC+t8ovsHnHKFI632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:C5B4C65B7806FC7F|rigid:B/JK2ZnPFhLISsu2zXFogaobS2E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A1U8QJX3	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2862844|uniprotkb:Q65AD4|uniprotkb:Q9ZGY7|uniprotkb:Q74YH2	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a1u8qjx3_yerpe(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862848|imex:IM-13779-6800	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"refseq:YP_094015.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:6MWRwyUiOxKAx7IdsuB8jghcr+I632	intact-crc:17ED5905D12FBA8F|rigid:J66gMEi2O4cpmnJfcxBYBp4zKH8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q65AE7	uniprotkb:P19838	intact:EBI-2847916|uniprotkb:A0A3N4BMH0|uniprotkb:Q9ZGZ5|uniprotkb:A0A384LBG0|uniprotkb:A0A1U8QRS1|uniprotkb:Q7ARB3	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q65ae7_yerpe(display_long)|uniprotkb:YPMT1.73(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862837|imex:IM-13779-6798	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025202|refseq:WP_002211757.1|refseq:NP_395419.1|refseq:YP_094002.1|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|interpro:IPR051406"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:BaOKn4oWF9wcKgOoNSaPk58oQ6k632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:F9B88FE0D792E519|rigid:R21S2eTI9n6CNhnIZJjC6UlepIQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARA1	uniprotkb:P19838	intact:EBI-2841424|uniprotkb:Q74YH4|uniprotkb:Q9ZGY6|uniprotkb:A0A380SBJ1|uniprotkb:A0A384LNJ3|uniprotkb:A0A1U8QRR1|uniprotkb:A0A2U2GUS2|uniprotkb:Q65AD2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q7ara1_yerpe(display_long)|uniprotkb:YPMT1.63Ac(gene name)|psi-mi:YPMT1.63Ac(display_short)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862855|imex:IM-13779-6801	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395408.1|refseq:YP_094017.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|refseq:WP_002211748.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:y3ME8oeVgFS46RADTemZrwD56RI632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:0CC922A9A75990CA|rigid:falf7R+STe6i2bJcABKJKf7GcOw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZGJ9	uniprotkb:P19838	intact:EBI-2845469|uniprotkb:Q8D025|uniprotkb:Q0WHC0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:rpia2_yerpe(display_long)|uniprotkb:rpiA2(gene name)|psi-mi:rpiA2(display_short)|uniprotkb:Phosphoriboisomerase A 2(gene name synonym)|uniprotkb:YPO1292(locus name)|uniprotkb:y2892(locus name)|uniprotkb:YP_1299(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862830|imex:IM-13779-6799	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|go:""GO:0004751""(ribose-5-phosphate isomerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006014""(D-ribose metabolic process)|go:""GO:0009052""(pentose-phosphate shunt, non-oxidative branch)|interpro:IPR037171|refseq:WP_002208805.1|refseq:YP_002346318.1|panther:PTHR11934(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:sddl00uN3G2aI0Hh5UEuroM7EKU632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:9AC7685B7ABC6D1C|rigid:mcnj8x53GVspu89QiAzi3QQGFEc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8D1A4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2850994	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q8d1a4_yerpe(display_long)|uniprotkb:y0798(locus name)|uniprotkb:fhuB(gene name)|psi-mi:fhuB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862906|imex:IM-13779-6804	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR000522(Bacterial transport system permease protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR037294"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:PGAfc4VH09eJJH0aF+uMggT6rQg632	intact-crc:62F1EDE57976858D|rigid:eTN/SmLnZ1WXJC1CouTnyUkOWpg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1G4	uniprotkb:P19838	intact:EBI-2862898|uniprotkb:Q74XJ9	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q8d1g4_yerpe(display_long)|uniprotkb:YP_0419(locus name)|uniprotkb:y0524(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862895|imex:IM-13779-6802	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012842(Type III secretion system HrpE/YscL)|go:""GO:0005737""(cytoplasm)|go:""GO:0030254""(protein secretion by the type III secretion system)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:BoaMivc89M9YA1PdUkJa4+4A53U632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:7DD7EDE579774F8E|rigid:ti16Gg0bo6FVarVSZzEN4AMBYz8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8D1M9	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2850328	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q8d1m9_yerpe(display_long)|uniprotkb:y0255(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862888|imex:IM-13779-6805	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR008727(PAAR)|interpro:IPR001826(RHS protein)|interpro:IPR022385|interpro:IPR006530(YD repeat)|interpro:IPR031325|go:""GO:0016020""(membrane)|interpro:IPR050708|interpro:IPR045351"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:Cab3pCzvfMqKzL/7edtHOtYi1fY632	intact-crc:71BDEDE57ABDE8DC|rigid:m7cKFFbUXUfMBknfH27VrhPkVSw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Z3B4	uniprotkb:P19838	intact:EBI-2862865|uniprotkb:Q7CI45|uniprotkb:Q74UP9|uniprotkb:A0A384K960|uniprotkb:A0A1U8QTH7|uniprotkb:A0A0H2W4B7|uniprotkb:A0A380PE05|uniprotkb:A0A2U2GZV2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q9z3b4_yerpe(display_long)|uniprotkb:int(gene name)|psi-mi:int(display_short)|uniprotkb:YPO1917(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862862|imex:IM-13779-6806	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:3RMP|interpro:IPR010998(Integrase, Lamba-type, N-terminal)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013762(Integrase-like, catalytic core, phage)|interpro:IPR002104(Integrase, catalytic core, phage)|rcsb pdb:3JTZ|interpro:IPR025166|interpro:IPR053876|refseq:WP_002212753.1|interpro:IPR050808|interpro:IPR038488|go:""GO:0003677""(DNA binding)|go:""GO:0006310""(DNA recombination)|go:""GO:0015074""(DNA integration)|interpro:IPR044068|refseq:YP_002346908.1|panther:PTHR30629(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:xnixEBDD4SZ0To5McLMlW4+CKBE632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:A5CD2C8608766033|rigid:MyCZSRW6ziRYGwNrhyhpgis5ly8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5L6A1	uniprotkb:P19838	intact:EBI-2862878	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a3g5l6a1_yerpe(display_long)|uniprotkb:tcbA(gene name)|psi-mi:tcbA(display_short)|uniprotkb:YP_3865(locus name)|uniprotkb:y0184(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862875|imex:IM-13779-6803	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A2U2H2J5(uniprot-removed-ac)|interpro:IPR040840|interpro:IPR041079|interpro:IPR046839|refseq:WP_002220204.1	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:kjRBO/f33i0tgY/JRYFkzLCun/4632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:A14D4321CCFF3038|rigid:AWimDiqgjXRUlR/uOaFDUH4WSHk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A5P8YGL4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2842269	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a5p8ygl4_yerpe(display_long)|uniprotkb:y2085(locus name)|uniprotkb:rnfC(gene name)|psi-mi:rnfC(display_short)|uniprotkb:Rnf electron transport complex subunit C(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862945|imex:IM-13779-6809	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR010208(Electron transport complex, RnfC)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR017896|interpro:IPR017900|interpro:IPR019554|interpro:IPR026902|interpro:IPR037225|refseq:WP_002223606.1|uniprotkb:Q8D0I9(uniprot-removed-ac)|go:""GO:0005886""(plasma membrane)|go:""GO:0009055""(electron transfer activity)|go:""GO:0022900""(electron transport chain)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:NRqQl9HrLq9sWIRyxpxhQ0JPxQo632	intact-crc:D5AD4DF5B404900B|rigid:O4bXSjNIn+5v1S0oLc5x8xm+i6I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D045	uniprotkb:P19838	intact:EBI-2843214|uniprotkb:Q74VS8	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q8d045_yerpe(display_long)|uniprotkb:y2788(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862952|imex:IM-13779-6811	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR041080|interpro:IPR003776(YcaO-like)	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:eDZjumGXqh186vyaDbx1D0kzPg8632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:C0C99CE57939A583|rigid:YrXdo/6Zd/oeR0OUz0t2VNVnnc8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6B3VAY1	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2862916	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6b3vay1_yerpe(display_long)|uniprotkb:y1149(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862913|imex:IM-13779-6807	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"uniprotkb:A0A6B3T2G6(uniprot-removed-ac)|interpro:IPR025997|interpro:IPR028082|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030313""(cell envelope)|refseq:WP_002223320.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:8pvc3jerUvIjDDfxLVAWia+XKng632	intact-crc:9C9E30EB1CA843A9|rigid:1K9DwQwFTx4Qbyb0dljYM8mTU6w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A5P8YHJ2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2862923	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a5p8yhj2_yerpe(display_long)|uniprotkb:YP_2645(locus name)|uniprotkb:y1460(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862927|imex:IM-13779-6810	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032674|interpro:IPR032675|uniprotkb:A0A6B3T2B6(uniprot-removed-ac)|interpro:IPR051071|go:""GO:0005576""(extracellular region)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:f/uy88ehczSoxQlZAXKXq86EZbM632	intact-crc:4292CE3F6AAA0FBF|rigid:aCyIbV2embPPEE3UvkPSLVCCT34	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8D0V3	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2862934|uniprotkb:Q74S74	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q8d0v3_yerpe(display_long)|uniprotkb:YP_2758(locus name)|uniprotkb:y1546(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862938|imex:IM-13779-6808	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	interpro:IPR010269(Protein of unknown function DUF877)|interpro:IPR044031|interpro:IPR044032	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:B/09d8cUU09y7I2C6BngKUErJC4632	intact-crc:106B9CE578E420B4|rigid:41MJmJWoIIjMGOCPp4fhXbqq1cc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8CZN4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2862981	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q8czn4_yerpe(display_long)|uniprotkb:y3760(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862984|imex:IM-13779-6813	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR032317|interpro:IPR006143(Secretion protein HlyD)|go:""GO:0009636""(response to toxic substance)|go:""GO:0016020""(membrane)|go:""GO:0022857""(transmembrane transporter activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:EiH5QICM0CrUOx+izcikVFr8gzY632	intact-crc:7DCCA4B27975E1B6|rigid:YKcnoc58awPoUzrNLnCqYf/w5Ww	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D007	uniprotkb:P19838	intact:EBI-2862962|uniprotkb:Q74WC7	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q8d007_yerpe(display_long)|uniprotkb:livK1(gene name)|psi-mi:livK1(display_short)|uniprotkb:YP_0949(locus name)|uniprotkb:y3002(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862959|imex:IM-13779-6814	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017777(ABC transporter, urea, substrate-binding, UrtA)|interpro:IPR000709(Leu/Ile/Val-binding protein)|interpro:IPR028082|go:""GO:0006865""(amino acid transport)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:6GTdEgyFALWYetGottXY9E7vDqw632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:C70D9CE57981288C|rigid:WYxL//eijdOmN/PtW84pkSL3beU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZZ4	uniprotkb:P19838	intact:EBI-2862971	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q8czz4_yerpe(display_long)|uniprotkb:y3093(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862974|imex:IM-13779-6812	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001248(Permease for cytosine/purines, uracil, thiamine, allantoin)|go:""GO:0016020""(membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR045225"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:m/ZE5JJrkSRLdqr1w29XibvJG+k632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:3F18A4B279715DBC|rigid:rthzgS50FvIFHoAVwRVcy0m64qo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZJ8	uniprotkb:P19838	intact:EBI-2862994	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q8czj8_yerpe(display_long)|uniprotkb:mrcA(gene name)|psi-mi:mrcA(display_short)|uniprotkb:y3924(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2862991|imex:IM-13779-6815	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR001264(Glycosyl transferase, family 51)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR036950|interpro:IPR023346|interpro:IPR031376|interpro:IPR050396|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008658""(penicillin binding)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016757""(glycosyltransferase activity)|go:""GO:0046677""(response to antibiotic)|go:""GO:0071555""(cell wall organization)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:yzvFBwKkloa4VAc0fEuZPlWHJ6o632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:9408A4B27AE09465|rigid:aXqO1le77o3IrRwqtX7YgtEnGic	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLE5	uniprotkb:P19838	intact:EBI-2846089	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q8cle5_yerpe(display_long)|uniprotkb:y1534(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863021|imex:IM-13779-6819	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010657(ImpA, N-terminal)|interpro:IPR017740(Type VI secretion system-associated, ImpA)	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:5eQsp+sABPR51bYxB3RJ2ZBfMr8632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:CFCF92B2792B1830|rigid:MhkgPjNBYCViZpgcE0fh5YoO5kY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZH3	uniprotkb:P19838	intact:EBI-2863002|uniprotkb:Q74QQ6	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q8czh3_yerpe(display_long)|uniprotkb:fimA7(gene name)|psi-mi:fimA7(display_short)|uniprotkb:YP_3406(locus name)|uniprotkb:y4063(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863007|imex:IM-13779-6820	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008966(Adhesion, bacterial)|interpro:IPR000259(Fimbrial protein)|interpro:IPR036937|interpro:IPR050263|go:""GO:0007155""(cell adhesion)|go:""GO:0009289""(pilus)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:G5uIaWDxwghrlSunGlo/LkNpPaU632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:15EAA4B278E2D7DB|rigid:iFY3yLF2NuAA5HWgUeaCVRlZzJk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A0H2W834	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2846024	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a0h2w834_yerpe(display_long)|uniprotkb:YP_3851(locus name)|uniprotkb:y0170(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863014|imex:IM-13779-6816	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	uniprotkb:A0A6B3T3V9(uniprot-removed-ac)|refseq:WP_011055205.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:saqLPnEWmzpLG+E2JzO8S+w+WY8632	intact-crc:2576E235EDB3B77F|rigid:ajsgLcKn52br8tOv8iAmv/RXfPI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GX04	uniprotkb:P19838	intact:EBI-2850302|uniprotkb:Q74RC2|uniprotkb:A0A0H2W7A4|uniprotkb:A0A5P8YAU6|uniprotkb:Q7CL05|uniprotkb:A0A384KDB1	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a2u2gx04_yerpe(display_long)|uniprotkb:YPO3906(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863038|imex:IM-13779-6818	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR053777|refseq:WP_002212022.1|refseq:YP_002348781.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:QOvYHsMlk2znb0YhwxWfUhF8SCQ632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:F80B7C63A85CB45F|rigid:jDANJFYF3b6ZJNV4IBhp0DOgP/k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CL24	uniprotkb:P19838	intact:EBI-2863028	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q8cl24_yerpe(display_long)|uniprotkb:y2336(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863031|imex:IM-13779-6817	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR015890(Chorismate binding, C-terminal)|go:""GO:0009058""(biosynthetic process)|go:""GO:0016829""(lyase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR019999"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:VqOyykdXuHOK4j+fXPoQJH2GklE632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:67C892B27964819C|rigid:LzG8DdG0zN2p/IGCGEI0BxWks+0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PJN0	uniprotkb:P19838	intact:EBI-2863048|uniprotkb:Q74XK8|uniprotkb:A0A0H2W2C2|uniprotkb:Q7CKS5|uniprotkb:A0A384K9K8|uniprotkb:A0A2U2GZC0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a380pjn0_yerpe(display_long)|uniprotkb:sctC(gene name)|psi-mi:sctC(display_short)|uniprotkb:YPO0257(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863045|imex:IM-13779-6821	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005644(NolW-like)|interpro:IPR004846(Type II and III secretion system)|interpro:IPR003522(Type III secretion system outer membrane pore YscC/HrcC)|interpro:IPR004845(Type II secretion system gspD, conserved site)|interpro:IPR050810|interpro:IPR038591|go:""GO:0009279""(cell outer membrane)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|interpro:IPR049034|refseq:YP_002345337.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:3E8zS3SC+p1nw/Frp/3LiBIvlh8632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:A3B6C70E56C19B2D|rigid:0AyoN2jXO1ZRvAT8SRygALz0sDw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A5P8YCU1	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2863067|uniprotkb:Q74X83|uniprotkb:Q0WBD6|uniprotkb:Q7CKJ8|uniprotkb:A0A384KP52	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a5p8ycu1_yerpe(display_long)|uniprotkb:cel(gene name)|psi-mi:cel(display_short)|uniprotkb:ispB(gene name synonym)|uniprotkb:YPO3513(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863064|imex:IM-13779-6822	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|refseq:WP_002210177.1|go:""GO:0004659""(prenyltransferase activity)|go:""GO:0008299""(isoprenoid biosynthetic process)|refseq:YP_002348402.1|panther:PTHR12001(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:unsp6Dp77exmehbrsQd4qVoTi20632	intact-crc:287EC7842F6ECD29|rigid:OjXNAK1bJ+JZcLlL+wRTzEhgCfs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W2Z9	uniprotkb:P19838	intact:EBI-2858874|uniprotkb:Q74XH6|uniprotkb:A0A5P8YBN3|uniprotkb:Q7CKQ6|uniprotkb:Q0WK16	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a0h2w2z9_yerpe(display_long)|uniprotkb:YPO0290(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863057|imex:IM-13779-6824	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR011215(Uncharacterised conserved protein UCP020979)|interpro:IPR028157|refseq:WP_002209070.1|interpro:IPR048336|refseq:YP_002345372.1	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:tkiAUX1x4Qx0pUonilOsHwLapVo632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:22517969251C61CF|rigid:OeSoH4XRZNl2pYv4n4iRu58UbuI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H0M8	uniprotkb:P19838	intact:EBI-2849144|uniprotkb:Q74XP9|uniprotkb:A0A3N4B5K6|uniprotkb:A0A0H2W284|uniprotkb:Q7CKB5|uniprotkb:A0A384KE37	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a2u2h0m8_yerpe(display_long)|uniprotkb:fumA(gene name)|psi-mi:fumA(display_short)|uniprotkb:fumB(gene name synonym)|uniprotkb:YPO3335(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863083|imex:IM-13779-6825	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020557|refseq:WP_002209418.1|interpro:IPR004646(Fe-S type hydro-lyases tartrate/fumarate alpha region)|interpro:IPR004647(Fe-S type hydro-lyases tartrate/fumarate beta region)|interpro:IPR011167(Iron-dependent fumarate hydratase)|go:""GO:0004333""(fumarate hydratase activity)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR036660|refseq:YP_002348231.1|interpro:IPR051208"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:+RE2hmq93gVFPvEwC+LKqnvbWt8632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:2F216BBAE88E9FD9|rigid:6guVO4sKBY06X4S2C13jk6dnpEY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WBG7	uniprotkb:P19838	intact:EBI-2844501|uniprotkb:Q74X58|uniprotkb:A0A0H2W1V8|uniprotkb:Q7CKH9|uniprotkb:A0A384LNE2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q0wbg7_yerpe(display_long)|uniprotkb:YPO3482(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863076|imex:IM-13779-6823	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR004764(Hydrophobe/amphiphile efflux-1 HAE1)|interpro:IPR027463|go:""GO:0005886""(plasma membrane)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:WP_002209267.1|refseq:YP_002348371.1|panther:PTHR32063(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:DInCv7/t33+/ny5k0SDBH7n6IWY632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:BEA1188DF1925C15|rigid:RrQyjj+PXcgkfDPEvIJEIk6S5Eo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q0WGB8	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2840297|uniprotkb:Q74UD5|uniprotkb:Q7CIZ0	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q0wgb8_yerpe(display_long)|uniprotkb:flhC(gene name)|psi-mi:flhC(display_short)|uniprotkb:YPO1663(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863120|imex:IM-13779-6827	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR007944(Flagellar transcriptional activator FlhC)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0044781""(bacterial-type flagellum organization)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:1902208""(regulation of bacterial-type flagellum assembly)|refseq:YP_002346670.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:v0QV1p9m6czrskYx+k6NlQGdTY0632	intact-crc:DABCAD8DF2E2759D|rigid:DrvzCz3tRM9IDx/WZ7jc13prFqs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PKY3	uniprotkb:P19838	intact:EBI-2863108|uniprotkb:Q74T57|uniprotkb:Q0WE04|uniprotkb:Q7CJ74|uniprotkb:A0A384L3Q4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a380pky3_yerpe(display_long)|uniprotkb:ybiB(gene name)|psi-mi:ybiB(display_short)|uniprotkb:YPO2522(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863113|imex:IM-13779-6829	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017459(Glycosyl transferase, family 3, N-terminal)|interpro:IPR035902|interpro:IPR036320|interpro:IPR005940(Anthranilate phosphoribosyl transferase)|refseq:WP_002210242.1|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004048""(anthranilate phosphoribosyltransferase activity)|go:""GO:0005829""(cytosol)|refseq:YP_002347484.1|panther:PTHR43285(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:iqRNJSTfie5rTGrU1kQFF6sssEw632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:0665DB049E45302B|rigid:Mfb2XYlfJTT8rOzO1AatYgJcNxg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A2U2H1Q2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2863090|uniprotkb:Q0WBY9|uniprotkb:Q7CK96|uniprotkb:A0A384KQ75|uniprotkb:A0A5P8YCL2	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a2u2h1q2_yerpe(display_long)|uniprotkb:yqaB(gene name)|psi-mi:yqaB(display_short)|uniprotkb:YPO3303(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863094|imex:IM-13779-6830	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR010976(Beta-phosphoglucomutase hydrolase)|interpro:IPR023214|interpro:IPR036412|interpro:IPR023198|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|refseq:WP_002209450.1|interpro:IPR051806|go:""GO:0016791""(phosphatase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR041492|refseq:YP_002348199.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:QcXanlipWSWRRFzC9TMAHb8yzBE632	intact-crc:F5461B109F4677C0|rigid:XVxyv8t8axWs8AzrJqzrJXatEdI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A3N4BEU0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863127|imex:IM-13779-6828	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	intact-crc:B45C7649B4A9B4E9|rigid:ZeFGYhEANxzip4FQogggcrT2noM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PE22	uniprotkb:P19838	intact:EBI-2856011|uniprotkb:A0A0H2W318|uniprotkb:Q74VW4|uniprotkb:Q7CJX4|uniprotkb:A0A384LD58	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a380pe22_yerpe(display_long)|uniprotkb:YPO2801(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863101|imex:IM-13779-6826	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR018677|refseq:WP_002209756.1|interpro:IPR025513|refseq:YP_002347742.1	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:dGYO2y8tXuDYlpLIte+D054U4jc632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:A3FF619CB8F49DFB|rigid:uDRj3KiKYUbv9w47bvcLvk9iP4s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W3E3	uniprotkb:P19838	intact:EBI-2857500|uniprotkb:Q74VI6|uniprotkb:A0A2S9PI91|uniprotkb:Q7CHC8|uniprotkb:Q0WHE2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a0h2w3e3_yerpe(display_long)|uniprotkb:bcr(gene name)|psi-mi:bcr(display_short)|uniprotkb:bicA(gene name synonym)|uniprotkb:bicR(gene name synonym)|uniprotkb:sur(gene name synonym)|uniprotkb:suxA(gene name synonym)|uniprotkb:YPO1267(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863158|imex:IM-13779-6833	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020846|interpro:IPR004812(Drug resistance transporter Bcr/CflA subfamily)|interpro:IPR011701(Major facilitator superfamily MFS-1)|refseq:WP_002208831.1|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR036259|refseq:YP_002346296.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:455JF+n6Oe6dlqZUuclJ+1lby2U632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:BF20FD50B7300328|rigid:UdbJ+XljrYD9LJNOsIdMdq8i14c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A0H2W496	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863165|imex:IM-13779-6835	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	intact-crc:99C46036B973B0F6|rigid:2+/1m6TBZcQ87dg7NZW3Km2bX2U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A5P8YES8	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2848652|uniprotkb:Q74US7|uniprotkb:A0A0H2W5A9|uniprotkb:Q7CHW1|uniprotkb:A0A384KDB2	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a5p8yes8_yerpe(display_long)|uniprotkb:sdaA(gene name)|psi-mi:sdaA(display_short)|uniprotkb:YPO1771(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863151|imex:IM-13779-6832	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR029009|interpro:IPR004644(Iron-sulphur-dependent L-serine dehydratase single chain form)|interpro:IPR005130(Serine dehydratase alpha chain)|interpro:IPR005131(Serine dehydratase beta chain)|refseq:WP_002211079.1|go:""GO:0003941""(L-serine ammonia-lyase activity)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:YP_002346768.1|interpro:IPR051318|panther:PTHR30182(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:yVnD/73Ksx+jEUDkJwTGNlx1tGM632	intact-crc:C452F8F37CD8EA8F|rigid:oZ+JLefymbOu7ICERycax28hyFY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A380PC31	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2847467|uniprotkb:Q74TQ8|uniprotkb:Q7CII9|uniprotkb:Q0WEL8	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a380pc31_yerpe(display_long)|uniprotkb:pntA(gene name)|psi-mi:pntA(display_short)|uniprotkb:YPO2303(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863134|imex:IM-13779-6831	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR026255|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR024605|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|refseq:WP_002211019.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006740""(NADPH regeneration)|go:""GO:0008750""(""proton-translocating NAD(P)+ transhydrogenase activity"")|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0050661""(NADP binding)|interpro:IPR036291|refseq:YP_002347270.1|panther:PTHR10160(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:FVP+mtiTI6lGXb+9R8nUXq43tEc632	intact-crc:4AC873E127162CCF|rigid:4GvX8WD2NQduLLiBpVhmzdDBX+4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A3N4B367	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2863141|uniprotkb:Q0WFG4|uniprotkb:Q7CI85|uniprotkb:A0A380PDB8	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a3n4b367_yerpe(display_long)|uniprotkb:YPO1989(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863144|imex:IM-13779-6834	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	interpro:IPR011652(MORN variant)|interpro:IPR006597(Sel1-like)|refseq:WP_002211266.1|interpro:IPR050767|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:YP_002346974.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:90CeAgAzRJUKRiKHIZi++P14aC8632	intact-crc:18395428761612BC|rigid:9dfX7W6jB0v9WqzESarxQRUQy0U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q0WJG4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2846925|uniprotkb:Q74Q34|uniprotkb:A0A0H2W9L2|uniprotkb:Q7CG92|uniprotkb:A0A384LN38	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q0wjg4_yerpe(display_long)|uniprotkb:YPO0501(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863201|imex:IM-13779-6837	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	interpro:IPR010269(Protein of unknown function DUF877)|interpro:IPR044031|interpro:IPR044032|refseq:YP_002345574.1|panther:PTHR35565(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:TPzgi5medwCHhWPuRdlCctI6gtQ632	intact-crc:EB4A908DF1775F79|rigid:t+DW0SGw+RfMrIw5QBOmzECW15w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WIV1	uniprotkb:P19838	intact:EBI-2863172|uniprotkb:Q74RJ4|uniprotkb:Q7CGK8|uniprotkb:A0A0H2W6A8	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q0wiv1_yerpe(display_long)|uniprotkb:flgE(gene name)|psi-mi:flgE(display_short)|uniprotkb:lfgE(gene name synonym)|uniprotkb:YPO0725(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863177|imex:IM-13779-6840	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR020013|interpro:IPR037058|interpro:IPR019776|interpro:IPR053967|refseq:WP_002211432.1|interpro:IPR037925|go:""GO:0005829""(cytosol)|go:""GO:0009288""(bacterial-type flagellum)|go:""GO:0009424""(bacterial-type flagellum hook)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071978""(bacterial-type flagellum-dependent swarming motility)|refseq:YP_002345787.1|panther:PTHR30435(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:zkM2GXHJ2mgffVXZR9pEBAb2XdA632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:954C038DF05DCE08|rigid:LoeDTlJi5iicLo7+9Hb6dmov1hw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PMX1	uniprotkb:P19838	intact:EBI-2863194|uniprotkb:Q0WJ74|uniprotkb:Q7CGD3	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a380pmx1_yerpe(display_long)|uniprotkb:YPO0592(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863191|imex:IM-13779-6839	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|refseq:WP_002210399.1|go:""GO:0004672""(protein kinase activity)|go:""GO:0005524""(ATP binding)|refseq:YP_002345664.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:ogWAyP+vJAPDgsMSON22WSQQKfw632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:32FEB825A221D4CC|rigid:OWYHz+pQNCsyVTrHCJ7al9Tap3s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A380PHU4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2850134|uniprotkb:Q0WKS5|uniprotkb:Q7CG26	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a380phu4_yerpe(display_long)|uniprotkb:resA(gene name synonym)|uniprotkb:polA(gene name)|psi-mi:polA(display_short)|uniprotkb:YPO0017(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863208|imex:IM-13779-6838	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR043502|interpro:IPR019760|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR020046|interpro:IPR020045|interpro:IPR002421(5'-3' exonuclease)|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR018320|interpro:IPR002298(DNA polymerase A)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR029060|refseq:WP_002213164.1|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006302""(double-strand break repair)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0008409""(5'-3' exonuclease activity)|interpro:IPR036279|interpro:IPR036397|refseq:YP_002345113.1|panther:PTHR10133(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:GygvBdt3VDWoMhC9L9UZrpc6vy0632	intact-crc:FB1C4928F0A15662|rigid:71u/sGb4IXYRR3JGxNV4+XTg5og	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A2S9PLQ4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2850273|uniprotkb:Q74RV3|uniprotkb:Q0WJ73|uniprotkb:Q7CGD4|uniprotkb:A0A0H2W7Y4	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a2s9plq4_yerpe(display_long)|uniprotkb:YPO0593(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863184|imex:IM-13779-6836	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	refseq:WP_002210398.1|interpro:IPR036457|refseq:YP_002345665.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:4kqACx6zUNpUs/XEEncBiVDWpxE632	intact-crc:6B6638A43B5FBC77|rigid:rvW0wLWKuB0NmARjsDsgNTq9AqM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A2U2H2G1	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2857421|uniprotkb:Q74Y18|uniprotkb:Q0WKD8|uniprotkb:Q7CFV8|uniprotkb:A0A384LDE1	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a2u2h2g1_yerpe(display_long)|uniprotkb:YPO0164(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863215|imex:IM-13779-6841	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR010100(TonB-dependent copper receptor)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|refseq:WP_002208882.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015344""(siderophore uptake transmembrane transporter activity)|go:""GO:0044718""(siderophore transmembrane transport)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002345250.1|panther:PTHR30069(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:OF3HwYfg6zaTqz0HTQ2WdTZ5Dv4632	intact-crc:1C22B033E9D81D9F|rigid:KQ86XnrJp6JlKPcud4Iym+Txxow	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:O68769	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2845621|uniprotkb:A0A384LBJ7|uniprotkb:Q74YJ8|uniprotkb:Q7ARC7|uniprotkb:Q7BT03|uniprotkb:A0A3G5LHP7|uniprotkb:A0A1U8QJV7|uniprotkb:A0A2U2H212	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:o68769_yerpe(display_long)|uniprotkb:YPMT1.55c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863248|imex:IM-13779-6845	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"refseq:NP_395400.1|refseq:YP_093945.1|refseq:NP_857688.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|refseq:WP_002213143.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:nQbvf/FMyfPAI9dWsYFXKmJ70HI632	intact-crc:FA2F9BB427131BD4|rigid:L7gxxktvFI7o/RnYG8Byt7aNSrA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YAM6	uniprotkb:P19838	intact:EBI-2844150|uniprotkb:Q7CFP2|uniprotkb:Q0W9V4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a5p8yam6_yerpe(display_long)|uniprotkb:malS(gene name)|psi-mi:malS(display_short)|uniprotkb:YPO4080(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863222|imex:IM-13779-6844	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014635(Alpha-amylase, MalS type)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209631.1|go:""GO:0004556""(alpha-amylase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0009313""(oligosaccharide catabolic process)|go:""GO:0030980""(alpha-glucan catabolic process)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348934.1|panther:PTHR10357(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:qjQekYtSF56tT51Uzp+xShmXohk632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:E1362ED4886074EC|rigid:CqVLv1mkLspU7Ok16+Nwodx2pG0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ18	uniprotkb:P19838	intact:EBI-2863239|uniprotkb:Q0WJZ5	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:plsb_yerpe(display_long)|uniprotkb:plsB(gene name)|psi-mi:plsB(display_short)|uniprotkb:YPO0312(locus name)|uniprotkb:y0570(locus name)|uniprotkb:YP_0468(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863236|imex:IM-13779-6843	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR022284|interpro:IPR028354|refseq:WP_002214644.1|go:""GO:0004366""(glycerol-3-phosphate O-acyltransferase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0008654""(phospholipid biosynthetic process)|go:""GO:0016024""(CDP-diacylglycerol biosynthetic process)|interpro:IPR041728|refseq:YP_002345393.1|interpro:IPR045520|panther:PTHR12563(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:6kFcCEfWa+m+xyS2jcIVQT2J0TM632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:99CF555B7AF0637E|rigid:33qjiJbUJh//9BteZNmKZJUlLC8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q9RID8	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2859217|uniprotkb:A0A3G5LBF7|uniprotkb:A0A384LNJ8|uniprotkb:Q7BTU6|uniprotkb:A0A2S9PDW1|uniprotkb:A0A380PG85	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q9rid8_yerpe(display_long)|uniprotkb:YPMT1.33(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863229|imex:IM-13779-6842	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"refseq:WP_002214134.1|refseq:NP_857670.1|interpro:IPR003223(Flagellin phase1 repressor)|refseq:NP_395371.1|go:""GO:0003700""(DNA-binding transcription factor activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:Gai8ohATJMOb+TpT/VpPGU9fdDw632	intact-crc:6DB7FD0E0BE3BCB2|rigid:qPINj5OspU9Orj/V3Q5Ks24pYDo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:O68699	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2863258|uniprotkb:Q74YX3|uniprotkb:Q7ARJ1|uniprotkb:A0A0H2W168|uniprotkb:A0A380SDE6|uniprotkb:A0A2S9PED1	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:o68699_yerpe(display_long)|uniprotkb:yopD(gene name)|psi-mi:yopD(display_short)|uniprotkb:Y0053(gene name synonym)|uniprotkb:YPCD1.28c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863255|imex:IM-13779-6850	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	refseq:NP_857754.1|refseq:NP_857949.1|interpro:IPR008898(YopD)|refseq:NP_395162.1|mint:O68699|refseq:WP_002212987.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:wIJgJUGGHZSulW8aNQiZGgZyrc4632	intact-crc:832DEAB427106A8F|rigid:Y/rWOn0VA2nNz+Thmw0IBttdsnI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8ZCK2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2844238|uniprotkb:Q0WCT2	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:mnth_yerpe(display_long)|uniprotkb:mntH(gene name)|psi-mi:mntH(display_short)|uniprotkb:YPO2982(locus name)|uniprotkb:y1500(locus name)|uniprotkb:YP_2607(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863285|imex:IM-13779-6847	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR001046(Natural resistance-associated macrophage protein)|go:""GO:0005384""(manganese ion transmembrane transporter activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006828""(manganese ion transport)|go:""GO:0015086""(cadmium ion transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|go:""GO:0034755""(iron ion transmembrane transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0071281""(cellular response to iron ion)|refseq:WP_002211621.1|refseq:YP_002347906.1|panther:PTHR11706(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:zWKfJk5oio19xxchpmXI9whBTnE632	intact-crc:5FC3AC5B78BECAD0|rigid:nHZ1oZl81Yit55NXRhyPk6ddAH8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8ZGA9	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2863276|uniprotkb:Q0WH20	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:msba_yerpe(display_long)|uniprotkb:msbA(gene name)|psi-mi:msbA(display_short)|uniprotkb:Lipid A export ATP-binding/permease protein MsbA(gene name synonym)|uniprotkb:YPO1395(locus name)|uniprotkb:YP_1198(locus name)|uniprotkb:y2777(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863273|imex:IM-13779-6849	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011917(ABC transporter, lipid A export, MsbA)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR036640|interpro:IPR039421|interpro:IPR027417|refseq:WP_002211320.1|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034040""(ATPase-coupled lipid transmembrane transporter activity)|go:""GO:0055085""(transmembrane transport)|go:""GO:0140359""(ABC-type transporter activity)|refseq:YP_002346418.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:4/Wo5PU9Ghh4jEHAix3JqnkYcJs632	intact-crc:F6DC685B7ABE6FE6|rigid:rVFXJxUtqEtb0xA63zFb/Rtqk2I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:P58526	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2851618|uniprotkb:Q0WE76	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:mtox_yerpe(display_long)|uniprotkb:solA(gene name)|psi-mi:solA(display_short)|uniprotkb:YPO2448(locus name)|uniprotkb:y1742(locus name)|uniprotkb:YP_2268(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863266|imex:IM-13779-6846	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR023493|refseq:WP_002211850.1|go:""GO:0005829""(cytosol)|go:""GO:0008115""(sarcosine oxidase activity)|go:""GO:0050131""(N-methyl-L-amino-acid oxidase activity)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|refseq:YP_002347412.1|interpro:IPR045170|panther:PTHR10961(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:CVPINp8wGJnyzKPXSUk8Tm4az0w632	intact-crc:41D1556A99AC6F35|rigid:vYPPD2aqK9W0xTphRntayGpT3Z4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKC6	uniprotkb:P19838	intact:EBI-2863295	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:lpt_yerpe(display_long)|uniprotkb:thrL(gene name)|psi-mi:thrL(display_short)|uniprotkb:thr operon attenuator(gene name synonym)|uniprotkb:YPO0458.1(locus name)|uniprotkb:YP_3723.1(locus name)|uniprotkb:y3719(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863292|imex:IM-13779-6848	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011720(Thr operon leader peptide)|refseq:WP_002231504.1|go:""GO:0009088""(threonine biosynthetic process)|go:""GO:0031556""(transcriptional attenuation by ribosome)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:CybiUDWjy7Pd81EDgK9MM7kHW8I632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:81FBC5B279CFD22E|rigid:DbV5ZmlyNUXcqlm+HMFq+VtjjE8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJF6	uniprotkb:P19838	intact:EBI-2863331|uniprotkb:Q0WKF0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:arob_yerpe(display_long)|uniprotkb:aroB(gene name)|psi-mi:aroB(display_short)|uniprotkb:YPO0152(locus name)|uniprotkb:y3934(locus name)|uniprotkb:YP_0154(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863336|imex:IM-13779-6855	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016037(3-dehydroquinate synthase AroB, subgroup)|interpro:IPR030960|interpro:IPR030963|refseq:WP_002208898.1|interpro:IPR050071|go:""GO:0000166""(nucleotide binding)|go:""GO:0003856""(3-dehydroquinate synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0009073""(aromatic amino acid family biosynthetic process)|go:""GO:0009423""(chorismate biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_002345238.1|panther:PTHR43622(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:oAaSV1yaes9+DFhFwx7wCcZNli8632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:9EC8555B79CEFD77|rigid:jDXL7eMsecuhX6IM2fPVFHfvzIk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8ZIH1	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2841326|uniprotkb:Q0WJD6	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:leud_yerpe(display_long)|uniprotkb:leuD(gene name)|psi-mi:leuD(display_short)|uniprotkb:Alpha-IPM isomerase(gene name synonym)|uniprotkb:Isopropylmalate isomerase(gene name synonym)|uniprotkb:YPO0530(locus name)|uniprotkb:y3648(locus name)|uniprotkb:YP_3652(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863303|imex:IM-13779-6851	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR004431(3-isopropylmalate dehydratase, small subunit region)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|go:""GO:0003861""(3-isopropylmalate dehydratase activity)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009316""(3-isopropylmalate dehydratase complex)|refseq:WP_002210456.1|refseq:YP_002345602.1|interpro:IPR033940|interpro:IPR050075|panther:PTHR43345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:lF0EK380WhlR7ondVqFIwVAnDFQ632	intact-crc:4C01C65B785B2C04|rigid:/hupFwRdsbONzXHUUq010hUQS80	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIL4	uniprotkb:P19838	intact:EBI-2852663|uniprotkb:Q0WJI3	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:carb_yerpe(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:YPO0482(locus name)|uniprotkb:YP_3697(locus name)|uniprotkb:y3692(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863324|imex:IM-13779-6853	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|refseq:WP_002210502.1|go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR033937|interpro:IPR036897|interpro:IPR036914|refseq:YP_002345555.1|panther:PTHR11405(orthology-group)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:l/RzabCD1P/dEo/AmaYoXpYV1FY632	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:3CC5C65B79755D65|rigid:toW/1gnJp9stAT8ddxd9bPIOiAA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8ZBK0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2862250|uniprotkb:Q0WBN7	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:cueo_yerpe(display_long)|uniprotkb:cueO(gene name)|psi-mi:cueO(display_short)|uniprotkb:Copper efflux oxidase(gene name synonym)|uniprotkb:Cuprous oxidase(gene name synonym)|uniprotkb:YPO3409(locus name)|uniprotkb:YP_0276(locus name)|uniprotkb:y0777(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863317|imex:IM-13779-6852	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR019546|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR002355(Multicopper oxidase, copper-binding site)|interpro:IPR008972(Cupredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|refseq:WP_002209340.1|go:""GO:0004322""(ferroxidase activity)|go:""GO:0005507""(copper ion binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002348301.1|interpro:IPR045087|panther:PTHR11709(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:b2wVZLVoAzwGS9U4iPLOm44PTeA632	intact-crc:4D1EDD5B7807347E|rigid:qfnNMA/mgqAHEPefZDkTDjA2xYE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q8ZEL9	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2858120|uniprotkb:Q0WF17	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:fadr_yerpe(display_long)|uniprotkb:fadR(gene name)|psi-mi:fadR(display_short)|uniprotkb:YPO2144(locus name)|uniprotkb:y2177(locus name)|uniprotkb:YP_1946(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863310|imex:IM-13779-6854	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR014178(Fatty acid response transcription factor FadR)|interpro:IPR008920(Fatty acid responsive transcription factor FadR, C-terminal)|interpro:IPR000524(Bacterial regulatory protein GntR, HTH)|interpro:IPR028374|refseq:WP_002211688.1|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0019217""(regulation of fatty acid metabolic process)|interpro:IPR036388|interpro:IPR036390|refseq:YP_002347121.1|panther:PTHR43537(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:BtgcqSpKLgoqX7IWTz50Z6ZY5/w632	intact-crc:145B8A5B7ABDA7A6|rigid:c/A8Knnkcwt1XCjiMY/x1HIwzws	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GVH6	uniprotkb:Q14494	intact:EBI-2863364|uniprotkb:Q74S71|uniprotkb:Q0WCX5|uniprotkb:Q7CJC9|uniprotkb:A0A384L768|uniprotkb:A0A5P8YHX0	intact:EBI-2804436|uniprotkb:Q96FN6|uniprotkb:Q12877|uniprotkb:D3DTU3|uniprotkb:D3DTU5|ensembl:ENSP00000354855.3|intact:EBI-28976146	psi-mi:a0a2u2gvh6_yerpe(display_long)|uniprotkb:YPO2934(locus name)	psi-mi:nf2l1_human(display_long)|uniprotkb:HBZ17(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:TCF11(gene name synonym)|uniprotkb:Locus control region-factor 1(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 1(gene name synonym)|uniprotkb:Transcription factor 11(gene name synonym)|uniprotkb:NFE2L1(gene name)|psi-mi:NFE2L1(display_short)|uniprotkb:Nuclear factor erythroid 2-related factor 1(gene name synonym)|uniprotkb:Protein NRF1, p120 form(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863368|imex:IM-13779-6857	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010263(Protein of unknown function DUF876, bacterial)|refseq:WP_002211571.1|refseq:YP_002347863.1	"refseq:NP_003195.1|refseq:XP_005257467.1|refseq:XP_005257469.1|ensembl:ENSG00000082641.16(gene)|ensembl:ENST00000362042.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008289""(lipid binding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0042802""(identical protein binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR047167|mint:Q14494|refseq:NP_001317191.1|panther:PTHR24411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vPzphvg70Pz73FURrrsYdZ0+RFw632	rogid:/mXRFWPHxGFlrQmbhG3eDz9uXoc9606	intact-crc:1BF842628152EAE1|rigid:7jKmCFpM3GCR5W/FnhC5bwVim6A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16621	uniprotkb:Q0WKD0	intact:EBI-726369|uniprotkb:Q07720|uniprotkb:Q6ICV9|ensembl:ENSP00000312436.4|ensembl:ENSP00000397185.2|ensembl:ENSP00000439120.2|ensembl:ENSP00000447558.1	intact:EBI-2842319|uniprotkb:Q74Y13|uniprotkb:A0A0H2W227|uniprotkb:Q7CFV4|uniprotkb:A0A2U2GZH9|uniprotkb:A0A384KL53	psi-mi:nfe2_human(display_long)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:NFE2(gene name)|psi-mi:NFE2(display_short)	psi-mi:q0wkd0_yerpe(display_long)|uniprotkb:YPO0174(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863343|imex:IM-13779-6859	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001248390.1|refseq:NP_001129495.1|refseq:NP_006154.1|refseq:XP_005268963.1|dip:DIP-57844N|ensembl:ENSG00000123405.14(gene)|ensembl:ENST00000312156.8(transcript)|ensembl:ENST00000435572.7(transcript)|ensembl:ENST00000540264.2(transcript)|ensembl:ENST00000553070.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006337""(nucleosome disassembly)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007599""(hemostasis)|go:""GO:0016605""(PML body)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0050699""(WW domain binding)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR047167|mint:Q16621|rcsb pdb:2KZ5|reactome:R-HSA-8936459|reactome:R-HSA-983231|panther:PTHR24411(orthology-group)"	"interpro:IPR010020(Integral membrane protein, YccS/YhfK)|interpro:IPR032692|go:""GO:0005886""(plasma membrane)|refseq:WP_002212296.1|refseq:YP_002345258.1|interpro:IPR049453"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Y8uGUXDj1DbJnvZT2aZ5suX/yDE9606	rogid:kcGMu3nqgZZDLIKTmhYWFPzUBcc632	intact-crc:A5FE96E15DEE93BF|rigid:hAg40ikdpMe6swV50mpjmkVi+iw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0V0	uniprotkb:Q14494	intact:EBI-2849272	intact:EBI-2804436|uniprotkb:Q96FN6|uniprotkb:Q12877|uniprotkb:D3DTU3|uniprotkb:D3DTU5|ensembl:ENSP00000354855.3|intact:EBI-28976146	psi-mi:q8d0v0_yerpe(display_long)|uniprotkb:fadL(gene name)|psi-mi:fadL(display_short)|uniprotkb:Outer membrane FadL protein(gene name synonym)|uniprotkb:Outer membrane flp protein(gene name synonym)|uniprotkb:y1577(locus name)	psi-mi:nf2l1_human(display_long)|uniprotkb:HBZ17(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:TCF11(gene name synonym)|uniprotkb:Locus control region-factor 1(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 1(gene name synonym)|uniprotkb:Transcription factor 11(gene name synonym)|uniprotkb:NFE2L1(gene name)|psi-mi:NFE2L1(display_short)|uniprotkb:Nuclear factor erythroid 2-related factor 1(gene name synonym)|uniprotkb:Protein NRF1, p120 form(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863357|imex:IM-13779-6858	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005017(Membrane protein involved in aromatic hydrocarbon degradation)|go:""GO:0006869""(lipid transport)|go:""GO:0009279""(cell outer membrane)"	"refseq:NP_003195.1|refseq:XP_005257467.1|refseq:XP_005257469.1|ensembl:ENSG00000082641.16(gene)|ensembl:ENST00000362042.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008289""(lipid binding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0042802""(identical protein binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR047167|mint:Q14494|refseq:NP_001317191.1|panther:PTHR24411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t3ttYDBykbAjdOq/JpJE2QGeyvk632	rogid:/mXRFWPHxGFlrQmbhG3eDz9uXoc9606	intact-crc:2D57B1AA5FBE7994|rigid:o+Xhd3tGVevJkeAzKueZFt5mLtk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13469	uniprotkb:Q8CL29	intact:EBI-716258|uniprotkb:B5B2N9|uniprotkb:Q13468|uniprotkb:Q5TFW7|uniprotkb:Q5TFW8|uniprotkb:Q9NPX6|uniprotkb:Q9NQH3|uniprotkb:Q9UJR2|uniprotkb:B5B2N8|uniprotkb:B5B2P2|uniprotkb:B5B2P3|uniprotkb:B5B2P0|ensembl:ENSP00000379330.3	intact:EBI-2843345	psi-mi:nfac2_human(display_long)|uniprotkb:T-cell transcription factor NFAT1(gene name synonym)|uniprotkb:NFAT pre-existing subunit(gene name synonym)|uniprotkb:NFATC2(gene name)|psi-mi:NFATC2(display_short)|uniprotkb:NFAT1(gene name synonym)|uniprotkb:NFATP(gene name synonym)	psi-mi:q8cl29_yerpe(display_long)|uniprotkb:y2328(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863350|imex:IM-13779-6856	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001245221.1|refseq:NP_036472.2|refseq:NP_775114.1|refseq:NP_001129493.1|refseq:NP_001245223.1|refseq:NP_001245225.1|dip:DIP-27630N|ensembl:ENSG00000101096.20(gene)|ensembl:ENST00000396009.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006974""(DNA damage response)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014904""(myotube cell development)|go:""GO:0016477""(cell migration)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0035976""(transcription factor AP-1 complex)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051216""(cartilage development)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0140742""(lncRNA transcription)|go:""GO:1901741""(positive regulation of myoblast fusion)|go:""GO:1905064""(negative regulation of vascular associated smooth muscle cell differentiation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008366(""Nuclear factor of activated T cells (NFAT)"")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032397|interpro:IPR037059|mint:Q13469|rcsb pdb:1A02|rcsb pdb:1OWR|rcsb pdb:1P7H|rcsb pdb:1PZU|rcsb pdb:1S9K|rcsb pdb:2AS5|rcsb pdb:2O93|rcsb pdb:3QRF|rcsb pdb:8OW4|rcsb pdb:8R07|rcsb pdb:8R3F|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-5607763|reactome:R-HSA-8877330|panther:PTHR12533(orthology-group)"	"interpro:IPR025993|interpro:IPR029044|go:""GO:0008120""(ceramide glucosyltransferase activity)|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SNvCfCooUb7MH1xO0prmM4jv+o49606	rogid:Pt/AIEe8E3IC1nZzNFeSEtiigHA632	intact-crc:DEBE2FC0537A9F36|rigid:sv1pdw/Ms7A+f4HX7YRvaFRjPlw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YDR4	uniprotkb:Q0ZGT2	intact:EBI-2860586|uniprotkb:Q74WD8|uniprotkb:Q0WHK1|uniprotkb:Q7CH88|uniprotkb:A0A384L6S5	intact:EBI-351705|uniprotkb:B4DPZ7|uniprotkb:A0PJ84|uniprotkb:Q0D2H2|uniprotkb:Q14CC2|uniprotkb:Q14CC3|uniprotkb:Q16081|uniprotkb:Q7Z2X0|uniprotkb:Q96DL0|uniprotkb:Q9Y2V1|intact:EBI-2555043|ensembl:ENSP00000333938.7	psi-mi:a0a5p8ydr4_yerpe(display_long)|uniprotkb:YPO1201(locus name)	psi-mi:nexn_human(display_long)|uniprotkb:F-actin-binding protein(gene name synonym)|uniprotkb:Nelin(gene name synonym)|uniprotkb:NEXN(gene name)|psi-mi:NEXN(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863375|imex:IM-13779-6860	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005308(Orn/Lys/Arg decarboxylase, N-terminal)|interpro:IPR011193(Ornithine/lysine/arginine decarboxylase)|interpro:IPR000310(Orn/Lys/Arg decarboxylase, major region)|interpro:IPR008286(Orn/Lys/Arg decarboxylase, C-terminal)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002210805.1|go:""GO:0005829""(cytosol)|go:""GO:0006527""(arginine catabolic process)|go:""GO:0008792""(arginine decarboxylase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR036633|refseq:YP_002346237.1|panther:PTHR45229(orthology-group)"	"efo:""Orphanet:154""|ensembl:ENSG00000162614.19(gene)|ensembl:ENST00000334785.12(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007411""(axon guidance)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030018""(Z disc)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0051015""(actin filament binding)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0070593""(dendrite self-avoidance)|go:""GO:0098632""(cell-cell adhesion mediator activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q0ZGT2|refseq:NP_001165780.1|refseq:NP_653174.3|refseq:XP_005271380.1|panther:PTHR10075(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9A69vMd4aUh4omR1oSM0/w+bz0Y632	rogid:YtKRiGq1tjrPhdFzpS5TKVn3So89606	intact-crc:CE8DAF9CF2A80BA9|rigid:9UOIqrc2p/nOVeSlZBDSw2KSwdo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P22392	uniprotkb:A0A0H2W1Q2	intact:EBI-713693|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6|ensembl:ENSP00000376886.1|ensembl:ENSP00000421064.1|ensembl:ENSP00000425581.1|ensembl:ENSP00000426901.1|ensembl:ENSP00000426976.2	intact:EBI-2841226|uniprotkb:Q0WBC6|uniprotkb:Q74X91|uniprotkb:Q7CKK4|uniprotkb:A0A380PGZ4	psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym)	psi-mi:a0a0h2w1q2_yerpe(display_long)|uniprotkb:YPO3523(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863406|imex:IM-13779-6863	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|ensembl:ENSG00000243678.12(gene)|ensembl:ENST00000393190.4(transcript)|ensembl:ENST00000503064.5(transcript)|ensembl:ENST00000512737.6(transcript)|ensembl:ENST00000513177.5(transcript)|ensembl:ENST00000514264.6(transcript)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0001726""(ruffle)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004550""(nucleoside diphosphate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006183""(GTP biosynthetic process)|go:""GO:0006228""(UTP biosynthetic process)|go:""GO:0006241""(CTP biosynthetic process)|go:""GO:0007155""(cell adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009142""(nucleoside triphosphate biosynthetic process)|go:""GO:0019003""(GDP binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045682""(regulation of epidermis development)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0051880""(G-quadruplex DNA binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|rcsb pdb:7KPF|rcsb pdb:8PIE|rcsb pdb:8PYW|reactome:R-HSA-499943|reactome:R-HSA-6798695|reactome:R-HSA-9748787|reactome:R-HSA-9755088|dip:DIP-50179N|panther:PTHR11349(orthology-group)"	"refseq:YP_002348412.1|interpro:IPR007452(Protein of unknown function DUF490)|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|refseq:WP_002210167.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606	rogid:EAskKEVuhdiV6Cq5qm8N8/ACmOw632	intact-crc:F2540E232733D457|rigid:YPnvf+yOzQAHWYy8Kw+HSCQ03Us	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P18615	uniprotkb:A0A2U2GZ90	intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|ensembl:ENSP00000364578.3|ensembl:ENSP00000372660.4|ensembl:ENSP00000372834.4|ensembl:ENSP00000393005.2|ensembl:ENSP00000394879.2|ensembl:ENSP00000403623.2|uniprotkb:A2BE08	intact:EBI-2863389|uniprotkb:Q0WF37|uniprotkb:Q7CIF5|uniprotkb:A0A384LDC3|uniprotkb:A0A5P8YGG5	psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym)	psi-mi:a0a2u2gz90_yerpe(display_long)|uniprotkb:YPO2123(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863392|imex:IM-13779-6864	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002895.3|ensembl:ENSG00000204356.14(gene)|ensembl:ENSG00000206268.11(gene)|ensembl:ENSG00000206357.11(gene)|ensembl:ENSG00000229363.9(gene)|ensembl:ENSG00000231044.10(gene)|ensembl:ENSG00000233801.9(gene)|ensembl:ENST00000375429.8(transcript)|ensembl:ENST00000383174.8(transcript)|ensembl:ENST00000383343.8(transcript)|ensembl:ENST00000429857.6(transcript)|ensembl:ENST00000448628.6(transcript)|ensembl:ENST00000457397.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0031401""(positive regulation of protein modification process)|go:""GO:0032021""(NELF complex)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|rcsb pdb:7YCX|rcsb pdb:8JJ6|rcsb pdb:8UHA|rcsb pdb:8UHD|rcsb pdb:8UHG|rcsb pdb:8UI0|rcsb pdb:8W8E|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N|panther:PTHR17250(orthology-group)"	"interpro:IPR038765|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR000064(NLP/P60)|interpro:IPR037518|interpro:IPR028090|refseq:WP_002211708.1|interpro:IPR051929|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347101.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606	rogid:HWnVp1gFkJHyyGCAHB8bjvW6FSQ632	intact-crc:2B6FD07A29D00904|rigid:0EHlRfCxAUNMrukEm8nvwMPPAdM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1F5	uniprotkb:Q9HB63	intact:EBI-2855341|uniprotkb:Q74XG8	intact:EBI-743459|uniprotkb:Q658K9|uniprotkb:Q7L3F1|uniprotkb:Q7L9D6|uniprotkb:Q7Z5B6|uniprotkb:Q9BZP1|uniprotkb:Q9NT44|uniprotkb:Q9P133|uniprotkb:B2RNC2|ensembl:ENSP00000340998.4	psi-mi:q8d1f5_yerpe(display_long)|uniprotkb:terD(gene name)|psi-mi:terD(display_short)|uniprotkb:YP_0456(locus name)|uniprotkb:y0559(locus name)	psi-mi:net4_human(display_long)|uniprotkb:Beta-netrin(gene name synonym)|uniprotkb:Hepar-derived netrin-like protein(gene name synonym)|uniprotkb:NTN4(gene name)|psi-mi:NTN4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863382|imex:IM-13779-6861	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051324|interpro:IPR003325(Bacterial stress protein)|go:""GO:0046690""(response to tellurium ion)"	"refseq:NP_067052.2|refseq:NP_001316629.1|refseq:NP_001316630.1|refseq:NP_001316631.1|dip:DIP-46274N|ensembl:ENSG00000074527.13(gene)|ensembl:ENST00000343702.9(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009888""(tissue development)|go:""GO:0016322""(neuron remodeling)|go:""GO:0016477""(cell migration)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0043237""(laminin-1 binding)|go:""GO:0043256""(laminin complex)|go:""GO:0060668""(regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling)|go:""GO:0070831""(basement membrane assembly)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|interpro:IPR035811|interpro:IPR050440|mint:Q9HB63|reactome:R-HSA-3000171|reactome:R-HSA-373752|panther:PTHR10574(orthology-group)|ensembl:ENSP00000340998.4|ensembl:ENST00000344911.8|ensembl:ENSP00000339436.4|ensembl:ENST00000538383.5|ensembl:ENSP00000444432.1|ensembl:ENST00000553059.1|ensembl:ENSP00000447292.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:GID0fZFhER54eVQ645Wu5Y80Fxo632	rogid:Wiq3R27SFsSneLrCDSpL19glpxE9606	intact-crc:587EF08BE1C2CF46|rigid:Bg5B3VEBCidNeA4okt070lgd/R4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TDX7	uniprotkb:Q7ARD3	intact:EBI-1055945|uniprotkb:A6NGT8|ensembl:ENSP00000356355.4|ensembl:ENSP00000444621.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:nek7_human(display_long)|uniprotkb:NEK7(gene name)|psi-mi:NEK7(display_short)|uniprotkb:Never in mitosis A-related kinase 7(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863399|imex:IM-13779-6862	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_598001.1|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|ensembl:ENSG00000151414.15(gene)|ensembl:ENST00000367385.9(transcript)|ensembl:ENST00000538004.5(transcript)|go:""GO:0000922""(spindle pole)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005874""(microtubule)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0032206""(positive regulation of telomere maintenance)|go:""GO:0032212""(positive regulation of telomere maintenance via telomerase)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035865""(cellular response to potassium ion)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140677""(molecular function activator activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8TDX7|rcsb pdb:2WQM|rcsb pdb:2WQN|rcsb pdb:5DE2|rcsb pdb:6NPY|rcsb pdb:6S73|rcsb pdb:6S75|rcsb pdb:6S76|rcsb pdb:8EJ4|rcsb pdb:8SXN|reactome:R-HSA-2980767|reactome:R-HSA-3301854|reactome:R-HSA-9648025|dip:DIP-50780N|panther:PTHR43289(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/25	rogid:2xAdwh1OOc1iBURvuTpckbOc7I09606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:9B75F6AAD2C6FF7D|rigid:0DeBf0ZX2jckg6XopxBSQUAUuJg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P22392	uniprotkb:Q8ZJJ5	intact:EBI-713693|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6|ensembl:ENSP00000376886.1|ensembl:ENSP00000421064.1|ensembl:ENSP00000425581.1|ensembl:ENSP00000426901.1|ensembl:ENSP00000426976.2	intact:EBI-2842956|uniprotkb:Q0WKJ3	psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym)	psi-mi:hslu_yerpe(display_long)|uniprotkb:hslU(gene name)|psi-mi:hslU(display_short)|uniprotkb:Unfoldase HslU(gene name synonym)|uniprotkb:YPO0105(locus name)|uniprotkb:y0294(locus name)|uniprotkb:YP_0107(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863413|imex:IM-13779-6865	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|ensembl:ENSG00000243678.12(gene)|ensembl:ENST00000393190.4(transcript)|ensembl:ENST00000503064.5(transcript)|ensembl:ENST00000512737.6(transcript)|ensembl:ENST00000513177.5(transcript)|ensembl:ENST00000514264.6(transcript)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0001726""(ruffle)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004550""(nucleoside diphosphate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006183""(GTP biosynthetic process)|go:""GO:0006228""(UTP biosynthetic process)|go:""GO:0006241""(CTP biosynthetic process)|go:""GO:0007155""(cell adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009142""(nucleoside triphosphate biosynthetic process)|go:""GO:0019003""(GDP binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045682""(regulation of epidermis development)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0051880""(G-quadruplex DNA binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071944""(cell periphery)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|rcsb pdb:7KPF|rcsb pdb:8PIE|rcsb pdb:8PYW|reactome:R-HSA-499943|reactome:R-HSA-6798695|reactome:R-HSA-9748787|reactome:R-HSA-9755088|dip:DIP-50179N|panther:PTHR11349(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR004491(Heat shock protein HslU)|interpro:IPR027417|go:""GO:0008233""(peptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0009376""(HslUV protease complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043335""(protein unfolding)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|refseq:WP_002208943.1|refseq:YP_002345195.1|interpro:IPR050052|panther:PTHR48102(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606	rogid:9NL3dzNGgq2JqZd7+stwnNgbDk0632	intact-crc:135BBA6DD246A141|rigid:JLCIjrnYgGsxj2eELHUy9szy1us	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZH37	uniprotkb:Q9Y618	intact:EBI-2851027|uniprotkb:Q0WHX0|uniprotkb:Q7CH28|uniprotkb:Q74S62	intact:EBI-80830|uniprotkb:Q9Y5U0|uniprotkb:O00613|uniprotkb:O15416|uniprotkb:Q13354|uniprotkb:O15421|intact:EBI-28976851|uniprotkb:Q56D06|uniprotkb:Q59GM0|ensembl:ENSP00000384018.1	psi-mi:gmhbb_yerpe(display_long)|uniprotkb:gmhB(gene name)|psi-mi:gmhB(display_short)|uniprotkb:D,D-heptose 1,7-bisphosphate phosphatase(gene name synonym)|uniprotkb:YPO1074(locus name)|uniprotkb:YP_2775(locus name)|uniprotkb:y3103(locus name)	psi-mi:ncor2_human(display_long)|uniprotkb:NCOR2(gene name)|psi-mi:NCOR2(display_short)|uniprotkb:CTG26(gene name synonym)|uniprotkb:Silencing mediator of retinoic acid and thyroid hormone receptor(gene name synonym)|uniprotkb:Thyroid-, retinoic-acid-receptor-associated corepressor(gene name synonym)|uniprotkb:T3 receptor-associating factor(gene name synonym)|uniprotkb:CTG repeat protein 26(gene name synonym)|uniprotkb:SMAP270(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863434|imex:IM-13779-6869	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006549(HAD-superfamily hydrolase, subfamily IIIA)|interpro:IPR004446(Histidinol phosphatase-related protein)|interpro:IPR006543(Histidinol-phosphate phosphatase)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009244""(lipopolysaccharide core region biosynthetic process)|go:""GO:0034200""(D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity)|go:""GO:0097171""(ADP-L-glycero-beta-D-manno-heptose biosynthetic process)|interpro:IPR036412|refseq:WP_002220062.1|refseq:YP_002346118.1|panther:PTHR42891(orthology-group)"	"refseq:NP_001070729.2|refseq:NP_001193583.1|refseq:NP_006303.4|panther:PTHR13992(orthology-group)|rcsb pdb:8B95|reactome:R-HSA-1989781|ensembl:ENSG00000196498.15(gene)|ensembl:ENST00000405201.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005112""(Notch binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007595""(lactation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0010565""(regulation of ketone metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016604""(nuclear body)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0021549""(cerebellum development)|go:""GO:0032355""(response to estradiol)|go:""GO:0035259""(nuclear glucocorticoid receptor binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044849""(estrous cycle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:1902894""(negative regulation of miRNA transcription)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|interpro:IPR051571|mint:Q9Y618|rcsb pdb:1KKQ|rcsb pdb:1R2B|rcsb pdb:1XC5|rcsb pdb:2GPV|rcsb pdb:2L5G|rcsb pdb:2LTP|rcsb pdb:2ODD|rcsb pdb:2RT5|rcsb pdb:3R29|rcsb pdb:3R2A|rcsb pdb:4A69|rcsb pdb:4OAR|rcsb pdb:5X8Q|rcsb pdb:5X8X|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6A22|rcsb pdb:6IVX|rcsb pdb:6PDZ|rcsb pdb:7SQA|rcsb pdb:8AQM|rcsb pdb:8AQN|rcsb pdb:8B8W|rcsb pdb:8B8X|rcsb pdb:8B8Y|rcsb pdb:8B8Z|rcsb pdb:8B90|rcsb pdb:8B91|rcsb pdb:8B92|rcsb pdb:8B93|rcsb pdb:8B94|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9841922|dip:DIP-951N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:TQJisFcuEi2sCw0MeU57QEi79XA632	rogid:58SZfHIXN3dZN93fsiVHbbEwD0g9606	intact-crc:CC0DFE84ECA5AAC3|rigid:90WWO/iKO8LPOz1wlnAjs520lGU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75376	uniprotkb:A0A2U2GUX9	intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|uniprotkb:B3DLF8|ensembl:ENSP00000268712.2	intact:EBI-2841416|uniprotkb:A0A0H2W940|uniprotkb:Q74PB0|uniprotkb:A0A384LLI5|uniprotkb:Q7CFN3|uniprotkb:A0A3N4BJ32	psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym)	psi-mi:a0a2u2gux9_yerpe(display_long)|uniprotkb:YPO4108(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863441|imex:IM-13779-6867	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-29402N|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1|refseq:XP_011522388.1|panther:PTHR13992(orthology-group)|ensembl:ENSG00000141027.23(gene)|ensembl:ENST00000268712.8(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0016020""(membrane)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045820""(negative regulation of glycolytic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045922""(negative regulation of fatty acid metabolic process)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0072686""(mitotic spindle)|go:""GO:1902894""(negative regulation of miRNA transcription)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|interpro:IPR051571|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3H52|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6WMS|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|rcsb pdb:8AS9|rcsb pdb:8D8I|rcsb pdb:8DKN|rcsb pdb:8DKV|rcsb pdb:8FHE|rcsb pdb:8FHG|rcsb pdb:8FKC|rcsb pdb:8FKD|rcsb pdb:8FKE|rcsb pdb:8FKF|rcsb pdb:8FKG|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|ensembl:ENSP00000268712.2|ensembl:ENST00000395848.5|ensembl:ENSP00000379189.1|ensembl:ENST00000395851.5|ensembl:ENSP00000379192.1"	"interpro:IPR023214|interpro:IPR041492|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002215575.1|refseq:YP_002348959.1|interpro:IPR023198|interpro:IPR036412|interpro:IPR051600"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606	rogid:N4DmZVhdbeJX1EvnC462dwFiaNU632	intact-crc:D8E38157866E549A|rigid:U4cMOD+koi19UzdIQD41qo6NW9M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y618	uniprotkb:P17778	intact:EBI-80830|uniprotkb:Q9Y5U0|uniprotkb:O00613|uniprotkb:O15416|uniprotkb:Q13354|uniprotkb:O15421|intact:EBI-28976851|uniprotkb:Q56D06|uniprotkb:Q59GM0|ensembl:ENSP00000384018.1	intact:EBI-2842665|uniprotkb:O68701	psi-mi:ncor2_human(display_long)|uniprotkb:NCOR2(gene name)|psi-mi:NCOR2(display_short)|uniprotkb:CTG26(gene name synonym)|uniprotkb:Silencing mediator of retinoic acid and thyroid hormone receptor(gene name synonym)|uniprotkb:Thyroid-, retinoic-acid-receptor-associated corepressor(gene name synonym)|uniprotkb:T3 receptor-associating factor(gene name synonym)|uniprotkb:CTG repeat protein 26(gene name synonym)|uniprotkb:SMAP270(gene name synonym)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863427|imex:IM-13779-6866	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001070729.2|refseq:NP_001193583.1|refseq:NP_006303.4|panther:PTHR13992(orthology-group)|rcsb pdb:8B95|reactome:R-HSA-1989781|ensembl:ENSG00000196498.15(gene)|ensembl:ENST00000405201.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005112""(Notch binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007595""(lactation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0010565""(regulation of ketone metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016604""(nuclear body)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0021549""(cerebellum development)|go:""GO:0032355""(response to estradiol)|go:""GO:0035259""(nuclear glucocorticoid receptor binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0044849""(estrous cycle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:1902894""(negative regulation of miRNA transcription)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|interpro:IPR051571|mint:Q9Y618|rcsb pdb:1KKQ|rcsb pdb:1R2B|rcsb pdb:1XC5|rcsb pdb:2GPV|rcsb pdb:2L5G|rcsb pdb:2LTP|rcsb pdb:2ODD|rcsb pdb:2RT5|rcsb pdb:3R29|rcsb pdb:3R2A|rcsb pdb:4A69|rcsb pdb:4OAR|rcsb pdb:5X8Q|rcsb pdb:5X8X|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6A22|rcsb pdb:6IVX|rcsb pdb:6PDZ|rcsb pdb:7SQA|rcsb pdb:8AQM|rcsb pdb:8AQN|rcsb pdb:8B8W|rcsb pdb:8B8X|rcsb pdb:8B8Y|rcsb pdb:8B8Z|rcsb pdb:8B90|rcsb pdb:8B91|rcsb pdb:8B92|rcsb pdb:8B93|rcsb pdb:8B94|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9841922|dip:DIP-951N"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:58SZfHIXN3dZN93fsiVHbbEwD0g9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:4603441FCBA4CF0E|rigid:uRV883OJHUGmiveYHwDbtTsgW2g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D194	uniprotkb:O60502	intact:EBI-2847851|uniprotkb:Q74XR4	intact:EBI-715814|uniprotkb:O75166|uniprotkb:Q86WV0|uniprotkb:Q8IV98|uniprotkb:Q9BVA5|uniprotkb:Q9HAR0|uniprotkb:B7WPB9|uniprotkb:D3DR79|uniprotkb:E9PGF9|ensembl:ENSP00000354850.3	psi-mi:q8d194_yerpe(display_long)|uniprotkb:dAK1_1(gene name)|psi-mi:dAK1_1(display_short)|uniprotkb:YP_0337(locus name)|uniprotkb:y0840(locus name)	psi-mi:oga_human(display_long)|uniprotkb:OGA(gene name)|psi-mi:OGA(display_short)|uniprotkb:Beta-N-acetylglucosaminidase(gene name synonym)|uniprotkb:Beta-N-acetylhexosaminidase(gene name synonym)|uniprotkb:Beta-hexosaminidase(gene name synonym)|uniprotkb:HEXC(gene name synonym)|uniprotkb:KIAA0679(gene name synonym)|uniprotkb:MEA5(gene name synonym)|uniprotkb:MGEA5(gene name synonym)|uniprotkb:Meningioma-expressed antigen 5(gene name synonym)|uniprotkb:N-acetyl-beta-D-glucosaminidase(gene name synonym)|uniprotkb:N-acetyl-beta-glucosaminidase(gene name synonym)|uniprotkb:Nuclear cytoplasmic O-GlcNAcase and acetyltransferase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863448|imex:IM-13779-6868	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004006(Dak kinase)|go:""GO:0004371""(glycerone kinase activity)|go:""GO:0006071""(glycerol metabolic process)|interpro:IPR050861"	"refseq:NP_001135906.1|refseq:NP_036347.1|ensembl:ENSG00000198408.14(gene)|ensembl:ENST00000361464.8(transcript)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006044""(N-acetylglucosamine metabolic process)|go:""GO:0006493""(protein O-linked glycosylation)|go:""GO:0006516""(glycoprotein catabolic process)|go:""GO:0006517""(protein deglycosylation)|go:""GO:0009100""(glycoprotein metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016231""(beta-N-acetylglucosaminidase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0102571""(""[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity"")|interpro:IPR011496(Hyaluronidase eukaryotic/prokaryotic)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR051822|mint:O60502|rcsb pdb:2YDQ|rcsb pdb:5M7R|rcsb pdb:5M7S|rcsb pdb:5M7T|rcsb pdb:5M7U|rcsb pdb:5TKE|rcsb pdb:5UHK|rcsb pdb:5UHL|rcsb pdb:5UHO|rcsb pdb:5UHP|rcsb pdb:5UN8|rcsb pdb:5UN9|rcsb pdb:5VVO|rcsb pdb:5VVT|rcsb pdb:5VVU|rcsb pdb:5VVV|rcsb pdb:5VVX|rcsb pdb:6HKI|rcsb pdb:6PM9|rcsb pdb:7OU6|rcsb pdb:7YEH|rcsb pdb:8P0L|panther:PTHR13170(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PGSwAYXIFUUnJmzpLaHT1vlvQxc632	rogid:KEvP6+2BWwsxrs8hsIjQhKAQGVo9606	intact-crc:5AB1E6880F8BF011|rigid:KqBmqw+BBFYYKAw1/umdi5sQDB8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A7Y8RCW6	uniprotkb:Q9GZM8	intact:EBI-2845056|uniprotkb:Q7CKM5|uniprotkb:A0A5P8YBL8|uniprotkb:Q0WJU7	intact:EBI-928842|uniprotkb:Q86T80|uniprotkb:Q8TAR7|uniprotkb:Q9UH50|uniprotkb:B3KP93|intact:EBI-2557484|uniprotkb:D3DTS0|uniprotkb:J3QT32|ensembl:ENSP00000333982.7|intact:EBI-11041407	psi-mi:a0a7y8rcw6_yerpe(display_long)|uniprotkb:YPO0363(locus name)	psi-mi:ndel1_human(display_long)|uniprotkb:NDEL1(gene name)|psi-mi:NDEL1(display_short)|uniprotkb:Mitosin-associated protein 1(gene name synonym)|uniprotkb:EOPA(gene name synonym)|uniprotkb:MITAP1(gene name synonym)|uniprotkb:NUDEL(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863420|imex:IM-13779-6870	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR024393|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR011066(Mechanosensitive ion channel MscS, C-terminal)|interpro:IPR006685(Mechanosensitive ion channel MscS)|interpro:IPR011014(Mechanosensitive ion channel MscS, transmembrane-2)|interpro:IPR006686(Mechanosensitive ion channel MscS, conserved site)|interpro:IPR025692|go:""GO:0005886""(plasma membrane)|go:""GO:0008381""(mechanosensitive monoatomic ion channel activity)|interpro:IPR049142|interpro:IPR049278|interpro:IPR023408|refseq:YP_002345441.1|interpro:IPR052702"	"refseq:NP_110435.1|refseq:NP_001020750.1|ensembl:ENSG00000166579.16(gene)|ensembl:ENST00000334527.12(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000776""(kinetochore)|go:""GO:0001833""(inner cell mass cell proliferation)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007100""(mitotic centrosome separation)|go:""GO:0008017""(microtubule binding)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008090""(retrograde axonal transport)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0016477""(cell migration)|go:""GO:0021799""(cerebral cortex radially oriented cell migration)|go:""GO:0021955""(central nervous system neuron axonogenesis)|go:""GO:0031252""(cell leading edge)|go:""GO:0032418""(lysosome localization)|go:""GO:0033157""(regulation of intracellular protein transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0043014""(alpha-tubulin binding)|go:""GO:0043203""(axon hillock)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0051303""(establishment of chromosome localization)|go:""GO:0051642""(centrosome localization)|go:""GO:0060052""(neurofilament cytoskeleton organization)|go:""GO:0060053""(neurofilament cytoskeleton)|go:""GO:0140650""(radial glia-guided pyramidal neuron migration)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990138""(neuron projection extension)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9GZM8|rcsb pdb:2V66|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:XP_016880674.1|refseq:XP_016880676.1|dip:DIP-29554N|panther:PTHR10921(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/10	rogid:z6l0v0GxSQqbhV/esC/hffWqLG8632	rogid:AtOowum6Uvuo3WRFXzogoOiDSXk9606	intact-crc:3EA75B5241F690CF|rigid:FxHaarqP98eUQbHzuysa4QQkMbs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14686	uniprotkb:Q8CZT6	intact:EBI-78670|uniprotkb:A6NLF1|uniprotkb:Q9NTZ9|uniprotkb:Q9UH74|uniprotkb:Q9UK86|uniprotkb:B2RMN5|uniprotkb:E1P5P7|ensembl:ENSP00000351894.2|ensembl:ENSP00000363929.2	intact:EBI-2863462	psi-mi:ncoa6_human(display_long)|uniprotkb:NCOA6(gene name)|psi-mi:NCOA6(display_short)|uniprotkb:KIAA0181(gene name synonym)|uniprotkb:RAP250(gene name synonym)|uniprotkb:Amplified in breast cancer protein 3(gene name synonym)|uniprotkb:Cancer-amplified transcriptional coactivator ASC-2(gene name synonym)|uniprotkb:Activating signal cointegrator 2(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor-activating protein, 250 kDa(gene name synonym)|uniprotkb:Nuclear receptor coactivator RAP250(gene name synonym)|uniprotkb:Thyroid hormone receptor-binding protein(gene name synonym)|uniprotkb:AIB3(gene name synonym)|uniprotkb:TRBP(gene name synonym)	psi-mi:q8czt6_yerpe(display_long)|uniprotkb:y3428(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863465|imex:IM-13779-6874	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229468.1|refseq:NP_054790.2|panther:PTHR15690(orthology-group)|refseq:NP_001305169.1|dip:DIP-30934N|ensembl:ENSG00000198646.14(gene)|ensembl:ENST00000359003.7(transcript)|ensembl:ENST00000374796.6(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0009725""(response to hormone)|go:""GO:0019899""(enzyme binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|interpro:IPR026638|interpro:IPR032715|mint:Q14686|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|interpro:IPR051551|go:""GO:0019867""(outer membrane)|interpro:IPR043990"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/10	rogid:0PZz93t/oHYDVeiX+8NqjSlpNRo9606	rogid:MiLa9vLiNmbmMr4denBvKhQstG8632	intact-crc:E65BD2210CBEE6F7|rigid:0UwejvcfX/NCcDxbnwaHAy1nxuo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14686	uniprotkb:Q7CJM5	intact:EBI-78670|uniprotkb:A6NLF1|uniprotkb:Q9NTZ9|uniprotkb:Q9UH74|uniprotkb:Q9UK86|uniprotkb:B2RMN5|uniprotkb:E1P5P7|ensembl:ENSP00000351894.2|ensembl:ENSP00000363929.2	intact:EBI-2863482|uniprotkb:Q74S85	psi-mi:ncoa6_human(display_long)|uniprotkb:NCOA6(gene name)|psi-mi:NCOA6(display_short)|uniprotkb:KIAA0181(gene name synonym)|uniprotkb:RAP250(gene name synonym)|uniprotkb:Amplified in breast cancer protein 3(gene name synonym)|uniprotkb:Cancer-amplified transcriptional coactivator ASC-2(gene name synonym)|uniprotkb:Activating signal cointegrator 2(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor-activating protein, 250 kDa(gene name synonym)|uniprotkb:Nuclear receptor coactivator RAP250(gene name synonym)|uniprotkb:Thyroid hormone receptor-binding protein(gene name synonym)|uniprotkb:AIB3(gene name synonym)|uniprotkb:TRBP(gene name synonym)	psi-mi:bamb_yerpe(display_long)|uniprotkb:y1356(locus name)|uniprotkb:bamB(gene name)|psi-mi:bamB(display_short)|uniprotkb:YPO2876(locus name)|uniprotkb:YP_2742(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863479|imex:IM-13779-6873	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229468.1|refseq:NP_054790.2|panther:PTHR15690(orthology-group)|refseq:NP_001305169.1|dip:DIP-30934N|ensembl:ENSG00000198646.14(gene)|ensembl:ENST00000359003.7(transcript)|ensembl:ENST00000374796.6(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0009725""(response to hormone)|go:""GO:0019899""(enzyme binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|interpro:IPR026638|interpro:IPR032715|mint:Q14686|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922"	"interpro:IPR017687(Outer membrane assembly lipoprotein YfgL)|interpro:IPR018391|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|refseq:WP_002209814.1|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR015943(WD40/YVTN repeat-like)|go:""GO:0009279""(cell outer membrane)|go:""GO:0043165""(Gram-negative-bacterium-type cell outer membrane assembly)|go:""GO:0051205""(protein insertion into membrane)|refseq:YP_002347811.1|panther:PTHR32303(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/10	rogid:0PZz93t/oHYDVeiX+8NqjSlpNRo9606	rogid:P07KWiSbqESi36zb1f8q7B0/ZE8632	intact-crc:8BF576D8D35C9640|rigid:Uw0kaxrjR+LrXDN27eTg7W9LVM4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0R7	uniprotkb:Q8NI08	intact:EBI-2851663	intact:EBI-80799|uniprotkb:Q6IPQ4|uniprotkb:Q3LID6|uniprotkb:Q4G0V1|uniprotkb:Q5TF95|uniprotkb:Q6NE83|uniprotkb:Q86T89|uniprotkb:Q8N1W4|uniprotkb:B2RNS2|uniprotkb:B9EH71|uniprotkb:B7Z2C4|uniprotkb:G8JL91|ensembl:ENSP00000357341.3|ensembl:ENSP00000376269.2	psi-mi:q8d0r7_yerpe(display_long)|uniprotkb:y1701(locus name)	psi-mi:ncoa7_human(display_long)|uniprotkb:NCOA7(gene name)|psi-mi:NCOA7(display_short)|uniprotkb:ERAP140(gene name synonym)|uniprotkb:ESNA1(gene name synonym)|uniprotkb:Nbla00052(orf name)|uniprotkb:Nbla10993(orf name)|uniprotkb:140 kDa estrogen receptor-associated protein(gene name synonym)|uniprotkb:Estrogen nuclear receptor coactivator 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863455|imex:IM-13779-6871	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006914(Protein of unknown function DUF638, haemagglutinin/haemolysin putative)|go:""GO:0090729""(toxin activity)"	"refseq:XP_005266879.1|refseq:NP_001116314.1|refseq:NP_001186548.1|refseq:NP_001186549.1|refseq:NP_001186550.1|refseq:NP_001186551.1|refseq:NP_861447.3|panther:PTHR23354(orthology-group)|refseq:XP_006715403.1|refseq:XP_011533757.1|refseq:XP_016865758.1|refseq:XP_016865759.1|refseq:XP_016865760.1|refseq:XP_016865761.1|refseq:XP_016865762.1|refseq:XP_016865763.1|go:""GO:0016922""(nuclear receptor binding)|ensembl:ENSG00000111912.20(gene)|ensembl:ENST00000368357.7(transcript)|ensembl:ENST00000392477.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1900408""(negative regulation of cellular response to oxidative stress)|go:""GO:1902083""(negative regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR006571(TLDc)|interpro:IPR018392|interpro:IPR036779|mint:Q8NI08|rcsb pdb:7OBP|rcsb pdb:8AR6|rcsb pdb:8AR9"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/06	rogid:Ks3lO/T2b4EUIIi1eSL1nvjMQjw632	rogid:43s4eDHUFoRQJKdOkaXlCtVtzW89606	intact-crc:3B2A0CF8F615A100|rigid:8bnq7A+I8Z5qEvMtoghm92JbBMg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CFY4	uniprotkb:Q14686	intact:EBI-2839980|uniprotkb:Q0WA73	intact:EBI-78670|uniprotkb:A6NLF1|uniprotkb:Q9NTZ9|uniprotkb:Q9UH74|uniprotkb:Q9UK86|uniprotkb:B2RMN5|uniprotkb:E1P5P7|ensembl:ENSP00000351894.2|ensembl:ENSP00000363929.2	psi-mi:q7cfy4_yerpe(display_long)|uniprotkb:YPO3944(locus name)	psi-mi:ncoa6_human(display_long)|uniprotkb:NCOA6(gene name)|psi-mi:NCOA6(display_short)|uniprotkb:KIAA0181(gene name synonym)|uniprotkb:RAP250(gene name synonym)|uniprotkb:Amplified in breast cancer protein 3(gene name synonym)|uniprotkb:Cancer-amplified transcriptional coactivator ASC-2(gene name synonym)|uniprotkb:Activating signal cointegrator 2(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor-activating protein, 250 kDa(gene name synonym)|uniprotkb:Nuclear receptor coactivator RAP250(gene name synonym)|uniprotkb:Thyroid hormone receptor-binding protein(gene name synonym)|uniprotkb:AIB3(gene name synonym)|uniprotkb:TRBP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863491|imex:IM-13779-6875	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003344(Bacterial Ig-like, group 1)|interpro:IPR024519|interpro:IPR003535(Intimin bacterial adhesion mediator protein)|interpro:IPR008964(Invasin/intimin cell-adhesion)|interpro:IPR018392|refseq:YP_002348815.1|interpro:IPR016186(C-type lectin-like)|interpro:IPR048658|go:""GO:0007155""(cell adhesion)|go:""GO:0009279""(cell outer membrane)|interpro:IPR038177|refseq:WP_002228169.1|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036779|interpro:IPR051715|panther:PTHR39576(orthology-group)"	"refseq:NP_001229468.1|refseq:NP_054790.2|panther:PTHR15690(orthology-group)|refseq:NP_001305169.1|dip:DIP-30934N|ensembl:ENSG00000198646.14(gene)|ensembl:ENST00000359003.7(transcript)|ensembl:ENST00000374796.6(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0009725""(response to hormone)|go:""GO:0019899""(enzyme binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|interpro:IPR026638|interpro:IPR032715|mint:Q14686|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/10	rogid:HyjrywO1mfKosC2W72qtvq9hL6w632	rogid:0PZz93t/oHYDVeiX+8NqjSlpNRo9606	intact-crc:8DBF3AD8D304D6A7|rigid:FAK9uKeNGPLT492nsdkpfmiHmiA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14686	uniprotkb:Q8CKL9	intact:EBI-78670|uniprotkb:A6NLF1|uniprotkb:Q9NTZ9|uniprotkb:Q9UH74|uniprotkb:Q9UK86|uniprotkb:B2RMN5|uniprotkb:E1P5P7|ensembl:ENSP00000351894.2|ensembl:ENSP00000363929.2	intact:EBI-2849463|uniprotkb:Q74Q90	psi-mi:ncoa6_human(display_long)|uniprotkb:NCOA6(gene name)|psi-mi:NCOA6(display_short)|uniprotkb:KIAA0181(gene name synonym)|uniprotkb:RAP250(gene name synonym)|uniprotkb:Amplified in breast cancer protein 3(gene name synonym)|uniprotkb:Cancer-amplified transcriptional coactivator ASC-2(gene name synonym)|uniprotkb:Activating signal cointegrator 2(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor-activating protein, 250 kDa(gene name synonym)|uniprotkb:Nuclear receptor coactivator RAP250(gene name synonym)|uniprotkb:Thyroid hormone receptor-binding protein(gene name synonym)|uniprotkb:AIB3(gene name synonym)|uniprotkb:TRBP(gene name synonym)	psi-mi:q8ckl9_yerpe(display_long)|uniprotkb:y3289(locus name)|uniprotkb:YP_3600(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863472|imex:IM-13779-6872	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229468.1|refseq:NP_054790.2|panther:PTHR15690(orthology-group)|refseq:NP_001305169.1|dip:DIP-30934N|ensembl:ENSG00000198646.14(gene)|ensembl:ENST00000359003.7(transcript)|ensembl:ENST00000374796.6(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0009725""(response to hormone)|go:""GO:0019899""(enzyme binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|interpro:IPR026638|interpro:IPR032715|mint:Q14686|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922"	"go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/10	rogid:0PZz93t/oHYDVeiX+8NqjSlpNRo9606	rogid:reO+RwzsQmogxtNDIEQ2oey9+Bo632	intact-crc:38C9B3210FC8CCCD|rigid:Rj31xhCphx/11vz49jQVmUOgMOg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6Q9	uniprotkb:A0A5P8YGH4	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066.3|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	intact:EBI-2842137|uniprotkb:Q0WF29|uniprotkb:Q7CIG0	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:a0a5p8ygh4_yerpe(display_long)|uniprotkb:YPO2131(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863514|imex:IM-13779-6876	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151.19(gene)|ensembl:ENST00000371998.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035624""(receptor transactivation)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043697""(cell dedifferentiation)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070561""(vitamin D receptor signaling pathway)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|dip:DIP-30876N|ensembl:ENST00000371997.3|ensembl:ENSP00000361065.3|ensembl:ENSP00000361066.3|ensembl:ENST00000372004.7|ensembl:ENSP00000361073.1"	interpro:IPR015406(Protein of unknown function DUF1983)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032876|refseq:WP_002211698.1|interpro:IPR036116|refseq:YP_002347109.1|interpro:IPR053171|panther:PTHR36251(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/12	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	rogid:oOCFMN5J0JyZf3JZhYlAIr4sCxM632	intact-crc:307FD14841DEDBB4|rigid:/qPTHElW1XUyo+gB57NAQM7Nlrg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6Q9	uniprotkb:Q8ZIL5	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066.3|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	intact:EBI-2855644|uniprotkb:Q0WJI4	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:cara_yerpe(display_long)|uniprotkb:carA(gene name)|psi-mi:carA(display_short)|uniprotkb:Carbamoyl phosphate synthetase glutamine chain(gene name synonym)|uniprotkb:YPO0481(locus name)|uniprotkb:YP_3698(locus name)|uniprotkb:y3693(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863535|imex:IM-13779-6878	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151.19(gene)|ensembl:ENST00000371998.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035624""(receptor transactivation)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043697""(cell dedifferentiation)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070561""(vitamin D receptor signaling pathway)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|dip:DIP-30876N|ensembl:ENST00000371997.3|ensembl:ENSP00000361065.3|ensembl:ENSP00000361066.3|ensembl:ENST00000372004.7|ensembl:ENSP00000361073.1"	"interpro:IPR029062|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR017926|refseq:WP_002224759.1|interpro:IPR035686|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0004359""(glutaminase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005951""(carbamoyl-phosphate synthase complex)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|interpro:IPR050472|interpro:IPR036480|refseq:YP_002345554.1|panther:PTHR11405(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/12	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	rogid:jU7sTbYvJhDasXs9v10lgQwS/IE632	intact-crc:702805225E6E9BE1|rigid:HkZ8vcXxxkklgwT2DIe6BvllD68	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6Q9	uniprotkb:A0A5P8YAV7	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066.3|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	intact:EBI-2839792|uniprotkb:Q74QU9|uniprotkb:Q0WA24|uniprotkb:Q7CG16|uniprotkb:A0A0H2W8V3	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:a0a5p8yav7_yerpe(display_long)|uniprotkb:pelY(gene name)|psi-mi:pelY(display_short)|uniprotkb:YPO3994(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863521|imex:IM-13779-6879	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151.19(gene)|ensembl:ENST00000371998.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035624""(receptor transactivation)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043697""(cell dedifferentiation)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070561""(vitamin D receptor signaling pathway)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|dip:DIP-30876N|ensembl:ENST00000371997.3|ensembl:ENSP00000361065.3|ensembl:ENSP00000361066.3|ensembl:ENST00000372004.7|ensembl:ENSP00000361073.1"	"interpro:IPR010702(Periplasmic pectate lyase)|refseq:YP_002348864.1|refseq:WP_002209555.1|go:""GO:0016837""(carbon-oxygen lyase activity, acting on polysaccharides)|go:""GO:0042597""(periplasmic space)|go:""GO:0045490""(pectin catabolic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/12	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	rogid:TdSmcoWgW+r5eNyU5ieC4Vae68s632	intact-crc:C9742DCA269BF906|rigid:LuhjY63wSqGFQPef6BcrjElv7UY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0P1	uniprotkb:Q9HCD5	intact:EBI-2856506|uniprotkb:Q8ZFL9|uniprotkb:Q0WGA3	intact:EBI-2863498|uniprotkb:Q9H1F2|uniprotkb:Q6HA99|uniprotkb:Q9H2T2|uniprotkb:B2RTV9|uniprotkb:Q9H4Y9|uniprotkb:E1P5R0|ensembl:ENSP00000290231.6	psi-mi:chey_yerpe(display_long)|uniprotkb:cheY(gene name)|psi-mi:cheY(display_short)|uniprotkb:YPO1680(locus name)|uniprotkb:y1842(locus name)|uniprotkb:YP_1810(locus name)	psi-mi:ncoa5_human(display_long)|uniprotkb:NCOA5(gene name)|psi-mi:NCOA5(display_short)|uniprotkb:KIAA1637(gene name synonym)|uniprotkb:Coactivator independent of AF-2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863507|imex:IM-13779-6880	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:Q8D0P1|interpro:IPR011006(CheY-like)|interpro:IPR001789(Signal transduction response regulator, receiver region)|refseq:WP_002210873.1|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|interpro:IPR052048|refseq:YP_002346685.1|panther:PTHR43228(orthology-group)"	"ensembl:ENSG00000124160.12(gene)|ensembl:ENST00000290231.11(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|interpro:IPR052600|mint:Q9HCD5|rcsb pdb:1V95|rcsb pdb:2J7X|rcsb pdb:2J7Y|rcsb pdb:4ZI1|refseq:NP_066018.1|panther:PTHR23295(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wf5r24m07Zgglm31fBnlvBt1VVY632	rogid:OxiZZWrvRqepYlZiuTR4RqZWn1A9606	intact-crc:E423EDCE88BB36B5|rigid:SyIdym7fDAXBeitoB7QfDu+vef0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6Q9	uniprotkb:Q8ZIX0	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066.3|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	intact:EBI-2843533|uniprotkb:Q0WJU5	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:rsga_yerpe(display_long)|uniprotkb:rsgA(gene name)|psi-mi:rsgA(display_short)|uniprotkb:YPO0365(locus name)|uniprotkb:y0622(locus name)|uniprotkb:YP_0520(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863528|imex:IM-13779-6877	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151.19(gene)|ensembl:ENST00000371998.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035624""(receptor transactivation)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043697""(cell dedifferentiation)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070561""(vitamin D receptor signaling pathway)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|dip:DIP-30876N|ensembl:ENST00000371997.3|ensembl:ENSP00000361065.3|ensembl:ENSP00000361066.3|ensembl:ENST00000372004.7|ensembl:ENSP00000361073.1"	"interpro:IPR010914(EngC GTPase)|interpro:IPR004881(GTPase EngC)|interpro:IPR027417|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0019843""(rRNA binding)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0046872""(metal ion binding)|interpro:IPR030378|refseq:WP_002209142.1|refseq:YP_002345443.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR32120(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/12	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	rogid:rH6QCtn1mhukog75yh2CbD5VMPg632	intact-crc:C7FC05225F452577|rigid:qujGWt4YdwHNCn3j885Z1tSSgKY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P52298	uniprotkb:A0A2U2GUZ8	intact:EBI-464729|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5|ensembl:ENSP00000326806.5	intact:EBI-2858974|uniprotkb:Q74PU1|uniprotkb:A0A380PJ37|uniprotkb:Q0WJS3|uniprotkb:Q7CG32|uniprotkb:A0A384L519	psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name)	psi-mi:a0a2u2guz8_yerpe(display_long)|uniprotkb:YPO0388(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863549|imex:IM-13779-6884	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|panther:PTHR18847(orthology-group)|ensembl:ENSG00000114503.11(gene)|ensembl:ENST00000321256.10(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000339""(RNA cap binding)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0002191""(cap-dependent translational initiation)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005846""(nuclear cap binding complex)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0006408""(snRNA export from nucleus)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0008334""(histone mRNA metabolic process)|go:""GO:0008380""(RNA splicing)|go:""GO:0016071""(mRNA metabolic process)|go:""GO:0017069""(snRNA binding)|go:""GO:0031053""(primary miRNA processing)|go:""GO:0031124""(mRNA 3'-end processing)|go:""GO:0031442""(positive regulation of mRNA 3'-end processing)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0034518""(RNA cap binding complex)|go:""GO:0035194""(regulatory ncRNA-mediated post-transcriptional gene silencing)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0045292""(mRNA cis splicing, via spliceosome)|go:""GO:0046833""(positive regulation of RNA export from nucleus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR027157|interpro:IPR034148|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|rcsb pdb:8BY6|rcsb pdb:8PMP|rcsb pdb:8PNT|rcsb pdb:8SRR|rcsb pdb:8SUY|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-33246N"	interpro:IPR019292|refseq:WP_002209167.1|refseq:YP_002345465.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606	rogid:KAzzgB6fVtKcGVFVzqcVYB96Yyk632	intact-crc:B76CD510794220FE|rigid:4hZjz+/aKPUEXqiv5u/lUPXw+2o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GWL4	uniprotkb:P13591	intact:EBI-2842513|uniprotkb:Q74QF2|uniprotkb:Q0WIK2|uniprotkb:Q7CGX2|uniprotkb:A0A384KBZ2	intact:EBI-2846607|uniprotkb:Q96CJ3|uniprotkb:Q16209|uniprotkb:P13593|uniprotkb:A8K8T8|uniprotkb:Q15829|uniprotkb:Q16180|uniprotkb:Q05C58|uniprotkb:Q86X47|uniprotkb:Q59FL7|uniprotkb:P13592|ensembl:ENSP00000318472.8	psi-mi:a0a2u2gwl4_yerpe(display_long)|uniprotkb:YPO0835(locus name)	psi-mi:ncam1_human(display_long)|uniprotkb:NCAM1(gene name)|psi-mi:NCAM1(display_short)|uniprotkb:NCAM(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863563|imex:IM-13779-6883	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004700(Phosphotransferase system, sorbose-specific IIC subunit)|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|refseq:WP_002209879.1|interpro:IPR047835|refseq:YP_002345886.1|interpro:IPR050303|panther:PTHR32502(orthology-group)"	"refseq:NP_000606.3|refseq:NP_001070150.1|refseq:NP_001229537.1|refseq:NP_851996.2|ensembl:ENSG00000149294.18(gene)|ensembl:ENST00000316851.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071679""(commissural neuron axon guidance)|go:""GO:2001260""(regulation of semaphorin-plexin signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P13591|rcsb pdb:5LKN|rcsb pdb:2E3V|rcsb pdb:2HAZ|rcsb pdb:2VKW|rcsb pdb:2VKX|rcsb pdb:3MTR|rcsb pdb:5AEA|reactome:R-HSA-3000178|reactome:R-HSA-375165|reactome:R-HSA-419037|reactome:R-HSA-445144|reactome:R-HSA-5673001|reactome:R-HSA-877300|dip:DIP-59530N|panther:PTHR12231(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:sFFGuU7nv2zkwyFSwvZPy1xxJLc632	rogid:v8l4lY/3tmSu4zQEcS0DV1nDGvI9606	intact-crc:1EC9CDEBF9B14D39|rigid:nmExElsUsLDuj5hbEQ1Ppo2WbWA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIH1	uniprotkb:Q8N660	intact:EBI-2841326|uniprotkb:Q0WJD6	intact:EBI-2863570|uniprotkb:A8MPT6|uniprotkb:Q3BBV9|uniprotkb:Q5SXJ2|uniprotkb:Q8IX77|intact:EBI-8476726|intact:MINT-8417699|ensembl:ENSP00000462600.1|ensembl:ENSP00000463178.1|ensembl:ENSP00000481835.1|intact:EBI-28968964	psi-mi:leud_yerpe(display_long)|uniprotkb:leuD(gene name)|psi-mi:leuD(display_short)|uniprotkb:Alpha-IPM isomerase(gene name synonym)|uniprotkb:Isopropylmalate isomerase(gene name synonym)|uniprotkb:YPO0530(locus name)|uniprotkb:y3648(locus name)|uniprotkb:YP_3652(locus name)	psi-mi:nbpff_human(display_long)|uniprotkb:NBPF15(gene name)|psi-mi:NBPF15(display_short)|uniprotkb:NBPF16(gene name synonym)|uniprotkb:Neuroblastoma breakpoint family member 16(gene name synonym)|uniprotkb:Neuroblastoma breakpoint family member 15(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863575|imex:IM-13779-6885	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004431(3-isopropylmalate dehydratase, small subunit region)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|go:""GO:0003861""(3-isopropylmalate dehydratase activity)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009316""(3-isopropylmalate dehydratase complex)|refseq:WP_002210456.1|refseq:YP_002345602.1|interpro:IPR033940|interpro:IPR050075|panther:PTHR43345(orthology-group)"	"refseq:XP_016856566.1|refseq:NP_001164226.1|refseq:NP_775909.2|ensembl:ENSG00000266338.7(gene)|ensembl:ENST00000488031.6(transcript)|ensembl:ENST00000577412.6(transcript)|ensembl:ENST00000581897.7(transcript)|go:""GO:0005737""(cytoplasm)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR055306|mint:Q8N660|panther:PTHR14199(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lF0EK380WhlR7ondVqFIwVAnDFQ632	rogid:guAWZ1op9NzRflXheR0SsSzinoM9606	intact-crc:2C6EB2BDDE7E202B|rigid:9lyDV60OFwsimEzDtDwnOSRnxpo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15596	uniprotkb:Q8ZFB2	intact:EBI-81236|uniprotkb:Q14CD2|ensembl:ENSP00000399968.2	intact:EBI-2842002|uniprotkb:Q0WFY8|uniprotkb:Q8CWH3|uniprotkb:Q74UV7	psi-mi:ncoa2_human(display_long)|uniprotkb:NCOA2(gene name)|psi-mi:NCOA2(display_short)|uniprotkb:TIF2(gene name synonym)|uniprotkb:Transcriptional intermediary factor 2(gene name synonym)|uniprotkb:BHLHE75(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 75(gene name synonym)|uniprotkb:SRC2(gene name synonym)	psi-mi:flgh2_yerpe(display_long)|uniprotkb:flgH2(gene name)|psi-mi:flgH2(display_short)|uniprotkb:Basal body L-ring protein 2(gene name synonym)|uniprotkb:YPO1805(locus name)|uniprotkb:y2504(locus name)|uniprotkb:YP_1588(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863542|imex:IM-13779-6881	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006531.1|ensembl:ENSG00000140396.13(gene)|ensembl:ENST00000452400.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001162""(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0016604""(nuclear body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0017162""(aryl hydrocarbon receptor binding)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032570""(response to progesterone)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1904017""(cellular response to Thyroglobulin triiodothyronine)|go:""GO:1904179""(positive regulation of adipose tissue development)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028822|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15596|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1M2Z|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1P93|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1UHL|rcsb pdb:1YOK|rcsb pdb:1ZDT|rcsb pdb:1ZDU|rcsb pdb:1ZKY|rcsb pdb:2AO6|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2LDC|rcsb pdb:2P15|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2Q7J|rcsb pdb:2Q7L|rcsb pdb:2YJD|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3A9E|rcsb pdb:3CLD|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E7C|rcsb pdb:3E94|rcsb pdb:3ERD|rcsb pdb:3FUG|rcsb pdb:3GN8|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:3KWY|rcsb pdb:3KYT|rcsb pdb:3L0E|rcsb pdb:3L0J|rcsb pdb:3L0L|rcsb pdb:3O1D|rcsb pdb:3O1E|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3PLZ|rcsb pdb:3Q95|rcsb pdb:3R5M|rcsb pdb:3UP0|rcsb pdb:3UP3|rcsb pdb:4CSJ|rcsb pdb:4DOS|rcsb pdb:4E2J|rcsb pdb:4FHH|rcsb pdb:4FHI|rcsb pdb:4IA1|rcsb pdb:4IA2|rcsb pdb:4IA3|rcsb pdb:4IA7|rcsb pdb:4IQR|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4NIE|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4PLD|rcsb pdb:4PLE|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q0A|rcsb pdb:4Q13|rcsb pdb:4QE8|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4RUO|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:4WG0|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5APH|rcsb pdb:5APJ|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXP|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EC9|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5G3J|rcsb pdb:5G42|rcsb pdb:5G43|rcsb pdb:5G44|rcsb pdb:5G45|rcsb pdb:5G46|rcsb pdb:5G5W|rcsb pdb:5H1E|rcsb pdb:5HYR|rcsb pdb:5I4V|rcsb pdb:5IAW|rcsb pdb:5ICK|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5L11|rcsb pdb:5LGA|rcsb pdb:5LYQ|rcsb pdb:5MK4|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5NI5|rcsb pdb:5NI7|rcsb pdb:5NI8|rcsb pdb:5NIB|rcsb pdb:5Q17|rcsb pdb:5SYZ|rcsb pdb:5T1Z|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5U2D|rcsb pdb:5UAN|rcsb pdb:5VB3|rcsb pdb:5VB5|rcsb pdb:5VB6|rcsb pdb:5VB7|rcsb pdb:5VQK|rcsb pdb:5VQL|rcsb pdb:5WGQ|rcsb pdb:5WZX|rcsb pdb:5XPL|rcsb pdb:5Y1J|rcsb pdb:5Y49|rcsb pdb:5YP5|rcsb pdb:5YXB|rcsb pdb:5YXD|rcsb pdb:5YXJ|rcsb pdb:5YXL|rcsb pdb:5Z12|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6ESN|rcsb pdb:6HL1|rcsb pdb:6KKB|rcsb pdb:6KKE|rcsb pdb:6KNU|rcsb pdb:6KNV|rcsb pdb:6KNW|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6LIT|rcsb pdb:6OQX|rcsb pdb:6OQY|rcsb pdb:6OR1|rcsb pdb:6R7A|rcsb pdb:6R7J|rcsb pdb:6R7K|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6VC2|rcsb pdb:6VIF|rcsb pdb:7A77|rcsb pdb:7A78|rcsb pdb:7A79|rcsb pdb:7APO|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7BK4|rcsb pdb:7D42|rcsb pdb:7JHD|rcsb pdb:7JYD|rcsb pdb:7JYE|rcsb pdb:7KCO|rcsb pdb:7NEL|rcsb pdb:7NFB|rcsb pdb:7NKE|rcsb pdb:7OFI|rcsb pdb:7OFK|rcsb pdb:7PDQ|rcsb pdb:7PDT|rcsb pdb:7RAE|rcsb pdb:7RAF|rcsb pdb:7RKE|rcsb pdb:7SFO|rcsb pdb:7T2X|rcsb pdb:7TT8|rcsb pdb:7UW2|rcsb pdb:7UW4|rcsb pdb:7VUE|rcsb pdb:7W3P|rcsb pdb:7W3Q|rcsb pdb:7WLX|rcsb pdb:7WMG|rcsb pdb:7WMH|rcsb pdb:7WMJ|rcsb pdb:7WML|rcsb pdb:7WMN|rcsb pdb:7WMO|rcsb pdb:7YMK|rcsb pdb:8C1L|rcsb pdb:8DAF|rcsb pdb:8EV1|rcsb pdb:8EV2|rcsb pdb:8F8M|rcsb pdb:8GL7|rcsb pdb:8P9X|rcsb pdb:8PP0|rcsb pdb:8PWD|rcsb pdb:8PWE|rcsb pdb:8PWF|rcsb pdb:8PWM|rcsb pdb:8PZ6|rcsb pdb:8PZ7|rcsb pdb:8PZ8|rcsb pdb:8PZ9|rcsb pdb:8PZB|rcsb pdb:8VKZ|rcsb pdb:9EZ1|rcsb pdb:9EZ2|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5625886|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|refseq:NP_001308642.1|refseq:NP_001308632.1|refseq:NP_001308636.1|refseq:NP_001308640.1|refseq:NP_001308641.1|dip:DIP-5997N"	"interpro:IPR000527(Flagellar L-ring protein)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009427""(bacterial-type flagellum basal body, distal rod, L ring)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:WP_002211116.1|refseq:YP_002346800.1|panther:PTHR34933(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:dZP564B7sZPW/ro5h2CVE2XJJpk9606	rogid:K+hG2Y1XkdBPEZly69izKbuTRvo632	intact-crc:0359653A95EF9727|rigid:hPBdxIh/U4a1p/1nXzb9WpIllfI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A1U8QJX3	uniprotkb:P13591	intact:EBI-2862844|uniprotkb:Q65AD4|uniprotkb:Q9ZGY7|uniprotkb:Q74YH2	intact:EBI-2846607|uniprotkb:Q96CJ3|uniprotkb:Q16209|uniprotkb:P13593|uniprotkb:A8K8T8|uniprotkb:Q15829|uniprotkb:Q16180|uniprotkb:Q05C58|uniprotkb:Q86X47|uniprotkb:Q59FL7|uniprotkb:P13592|ensembl:ENSP00000318472.8	psi-mi:a0a1u8qjx3_yerpe(display_long)	psi-mi:ncam1_human(display_long)|uniprotkb:NCAM1(gene name)|psi-mi:NCAM1(display_short)|uniprotkb:NCAM(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863556|imex:IM-13779-6882	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_094015.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"refseq:NP_000606.3|refseq:NP_001070150.1|refseq:NP_001229537.1|refseq:NP_851996.2|ensembl:ENSG00000149294.18(gene)|ensembl:ENST00000316851.12(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071679""(commissural neuron axon guidance)|go:""GO:2001260""(regulation of semaphorin-plexin signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P13591|rcsb pdb:5LKN|rcsb pdb:2E3V|rcsb pdb:2HAZ|rcsb pdb:2VKW|rcsb pdb:2VKX|rcsb pdb:3MTR|rcsb pdb:5AEA|reactome:R-HSA-3000178|reactome:R-HSA-375165|reactome:R-HSA-419037|reactome:R-HSA-445144|reactome:R-HSA-5673001|reactome:R-HSA-877300|dip:DIP-59530N|panther:PTHR12231(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:6MWRwyUiOxKAx7IdsuB8jghcr+I632	rogid:v8l4lY/3tmSu4zQEcS0DV1nDGvI9606	intact-crc:81AF42DFAB87B2C2|rigid:/N6dzF5KBD7ZvuJvD4ANZBsYRmw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P68587	uniprotkb:P0C2Y1	intact:EBI-2844901|uniprotkb:P40295	intact:EBI-2863596	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	psi-mi:nbpf7_human(display_long)|uniprotkb:NBPF7P(gene name)|psi-mi:NBPF7P(display_short)|uniprotkb:NBPF7(gene name synonym)|uniprotkb:Putative neuroblastoma breakpoint family member 7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863593|imex:IM-13779-6886	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"refseq:NP_001041445.1|interpro:IPR010630(Protein of unknown function DUF1220)|go:""GO:0005737""(cytoplasm)|interpro:IPR055306|panther:PTHR14199(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	rogid:MSCWH1hP7ITQFG3o08Hn2siUAQA9606	intact-crc:5C4383B9450F12B3|rigid:RsbFnyhUZRJB3v6CpNw6TrpjlaE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1P8	uniprotkb:Q3BBV2	intact:EBI-2841883	intact:EBI-2863585|uniprotkb:A0A8V8TN03|ensembl:ENSP00000513610.1|intact:EBI-28968706	psi-mi:q8d1p8_yerpe(display_long)|uniprotkb:tcaA1(gene name)|psi-mi:tcaA1(display_short)|uniprotkb:y0183(locus name)	psi-mi:nbpf8_human(display_long)|uniprotkb:NBPF8(gene name)|psi-mi:NBPF8(display_short)|uniprotkb:NBPF8P(gene name synonym)|uniprotkb:Neuroblastoma breakpoint family member 8(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863582|imex:IM-13779-6888	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR018003	"ensembl:ENSG00000270231.5(gene)|ensembl:ENST00000698216.1(transcript)|go:""GO:0005737""(cytoplasm)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR055306|mint:Q3BBV2|refseq:NP_001032590.2|panther:PTHR14199(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:LfA2Lz71pTe9HDOA0UOS0/RgEsY632	rogid:wpV/tq3LNr8tR1eaNtDABt4eznE9606	intact-crc:7A578BE8434D0F58|rigid:kxY5qo/OJJR5C4VLMTyz4o8T2dA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZS30	uniprotkb:Q8ZFR1	intact:EBI-2809093|uniprotkb:Q8N8R4|uniprotkb:Q96Q31|uniprotkb:Q6Y876|uniprotkb:Q6ZQY5|uniprotkb:Q96Q30|uniprotkb:A6NHD5|intact:EBI-2863604|uniprotkb:Q6ZP36|ensembl:ENSP00000399903.1	intact:EBI-2845635|uniprotkb:Q0WGE7	psi-mi:nbel1_human(display_long)|uniprotkb:NBEAL1(gene name)|psi-mi:NBEAL1(display_short)|uniprotkb:ALS2CR16(gene name synonym)|uniprotkb:ALS2CR17(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein(gene name synonym)	psi-mi:npd_yerpe(display_long)|uniprotkb:cobB(gene name)|psi-mi:cobB(display_short)|uniprotkb:Regulatory protein SIR2 homolog(gene name synonym)|uniprotkb:YPO1630(locus name)|uniprotkb:y1790(locus name)|uniprotkb:YP_1760(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863617|imex:IM-13779-6887	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001107604.1|ensembl:ENSG00000144426.19(gene)|ensembl:ENST00000449802.5(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|interpro:IPR046851|interpro:IPR050865|panther:PTHR13743(orthology-group)"	"interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR027546|interpro:IPR029035|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0017136""(histone deacetylase activity, NAD-dependent)|go:""GO:0032041""(histone H3K14 deacetylase activity, NAD-dependent)|go:""GO:0036054""(protein-malonyllysine demalonylase activity)|go:""GO:0036055""(protein-succinyllysine desuccinylase activity)|go:""GO:0046969""(histone H3K9 deacetylase activity, NAD-dependent)|go:""GO:0046970""(histone H4K16 deacetylase activity, NAD-dependent)|go:""GO:0070403""(NAD+ binding)|go:""GO:0097372""(histone H3K18 deacetylase activity, NAD-dependent)|go:""GO:0140765""(histone H3K56 deacetylase activity, NAD-dependent)|go:""GO:0141222""(histone H3K4 deacetylase activity, NAD-dependent)|go:""GO:0160013""(NAD-dependent protein de-2-hydroxyisobutyrylase activity)|refseq:WP_002210921.1|interpro:IPR026591|refseq:YP_002346641.1|interpro:IPR050134|panther:PTHR11085(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WVn2v6T+2goH2bDo+010vjmzk049606	rogid:Vx6TsEbqJmwcaje73uVtMzJ0+QA632	intact-crc:8523F992283A3E13|rigid:uDO0QffjxlCpmvv0neSl1doJ4Qc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CWG4	uniprotkb:Q8NFP9	intact:EBI-2856530|uniprotkb:Q74QZ9	intact:EBI-723014|uniprotkb:B7Z2H9|uniprotkb:Q9HCM8|uniprotkb:Q9NSU1|uniprotkb:Q9NW98|uniprotkb:Q9Y6J1|uniprotkb:Q5T320|ensembl:ENSP00000383295.3	psi-mi:q8cwg4_yerpe(display_long)|uniprotkb:glpD(gene name)|psi-mi:glpD(display_short)|uniprotkb:YP_3299(locus name)|uniprotkb:y3891(locus name)	psi-mi:nbea_human(display_long)|uniprotkb:Lysosomal-trafficking regulator 2(gene name synonym)|uniprotkb:Protein BCL8B(gene name synonym)|uniprotkb:NBEA(gene name)|psi-mi:NBEA(display_short)|uniprotkb:BCL8B(gene name synonym)|uniprotkb:KIAA1544(gene name synonym)|uniprotkb:LYST2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863624|imex:IM-13779-6889	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR031656|go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0006072""(glycerol-3-phosphate metabolic process)|go:""GO:0009331""(""glycerol-3-phosphate dehydrogenase (FAD) complex"")|interpro:IPR038299|interpro:IPR036188"	"efo:""Orphanet:178469""|ensembl:ENSG00000172915.20(gene)|ensembl:ENST00000400445.8(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008104""(protein localization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR010508(Protein of unknown function DUF1088)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|interpro:IPR046851|interpro:IPR046852|interpro:IPR050865|mint:Q8NFP9|rcsb pdb:1MI1|reactome:R-HSA-112314|reactome:R-HSA-163615|reactome:R-HSA-2122947|reactome:R-HSA-9609736|refseq:NP_001191126.1|refseq:NP_056493.3|panther:PTHR13743(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:R9I22ZXVmXiKYYz/+NgwNjlHCb0632	rogid:gfO4KOqPksy4F827O5y71CM6zPU9606	intact-crc:F0C7AC62ACDA420D|rigid:IV2Tc25Jv6ar4cnS9ZvWXiDgZdA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ10	uniprotkb:Q9C000	intact:EBI-2845732|uniprotkb:Q0WJY7	intact:EBI-1220518|uniprotkb:Q9BZZ8|uniprotkb:Q9BZZ9|uniprotkb:Q9HAV8|uniprotkb:Q9UFT4|uniprotkb:Q9Y2E0|uniprotkb:E9PE50|uniprotkb:I6L9D9|uniprotkb:Q9H5Z7|uniprotkb:Q9H5Z8|ensembl:ENSP00000460475.1|ensembl:ENSP00000478516.1|ensembl:ENSP00000514534.1	psi-mi:alr_yerpe(display_long)|uniprotkb:alr(gene name)|psi-mi:alr(display_short)|uniprotkb:YPO0321(locus name)|uniprotkb:YP_0476(locus name)|uniprotkb:y0578(locus name)	psi-mi:nlrp1_human(display_long)|uniprotkb:NLRP1(gene name)|psi-mi:NLRP1(display_short)|uniprotkb:CARD7(gene name synonym)|uniprotkb:DEFCAP(gene name synonym)|uniprotkb:KIAA0926(gene name synonym)|uniprotkb:NAC(gene name synonym)|uniprotkb:NALP1(gene name synonym)|uniprotkb:Death effector filament-forming ced-4-like apoptosis protein(gene name synonym)|uniprotkb:Nucleotide-binding domain and caspase recruitment domain(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863675|imex:IM-13779-6892	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000821(Alanine racemase region)|interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR011079(Alanine racemase, C-terminal)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR020622|interpro:IPR029066|refseq:WP_002209096.1|go:""GO:0005829""(cytosol)|go:""GO:0008784""(alanine racemase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0030632""(D-alanine biosynthetic process)|refseq:YP_002345401.1|panther:PTHR30511(orthology-group)"	"efo:""Orphanet:352662""|ensembl:ENSG00000091592.17(gene)|ensembl:ENST00000572272.6(transcript)|ensembl:ENST00000617618.5(transcript)|ensembl:ENST00000699709.1(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0002221""(pattern recognition receptor signaling pathway)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0008233""(peptidase activity)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051607""(defense response to virus)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0071493""(cellular response to UV-B)|go:""GO:0072558""(NLRP1 inflammasome complex)|go:""GO:0072559""(NLRP3 inflammasome complex)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097264""(self proteolysis)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140608""(cysteine-type endopeptidase activator activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1904784""(NLRP1 inflammasome complex assembly)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR004020(Pyrin)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|interpro:IPR027417|interpro:IPR032675|interpro:IPR033516|interpro:IPR041075|rcsb pdb:7WGE|interpro:IPR041267|interpro:IPR051249|mint:Q9C000|rcsb pdb:1PN5|rcsb pdb:3KAT|rcsb pdb:4IFP|rcsb pdb:4IM6|rcsb pdb:5Y3S|rcsb pdb:6K7V|rcsb pdb:6X6C|rcsb pdb:6XKK|rcsb pdb:8ZGD|reactome:R-HSA-844455|refseq:NP_001028225.1|refseq:NP_055737.1|refseq:NP_127497.1|refseq:NP_127499.1|refseq:NP_127500.1|dip:DIP-38407N|panther:PTHR46985(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DHbxD7IyYyhVi917Zw+/1ybH+hI632	rogid:tlXizUa/MP9AnLH5RpYPMcCB3UY9606	intact-crc:9DF0C602360E733E|rigid:G5aFb2XbeNfwzoA+mCtn1u8sI/0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43490	uniprotkb:A0A2S9PKV8	intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553.3|ensembl:ENSP00000390591.2|ensembl:ENSP00000506129.1|ensembl:ENSP00000506540.1|intact:EBI-21359121	intact:EBI-2859198|uniprotkb:Q74WD4|uniprotkb:Q0WHK6|uniprotkb:Q7CH84|uniprotkb:A0A384KBV6	psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym)	psi-mi:a0a2s9pkv8_yerpe(display_long)|uniprotkb:YPO1194(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863661|imex:IM-13779-6893	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005737.1|refseq:XP_005250157.1|ensembl:ENSG00000105835.13(gene)|ensembl:ENST00000222553.8(transcript)|ensembl:ENST00000424768.2(transcript)|ensembl:ENST00000681255.1(transcript)|ensembl:ENST00000681491.1(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009435""(NAD biosynthetic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0030054""(cell junction)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0034356""(obsolete NAD biosynthesis via nicotinamide riboside salvage pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0047280""(nicotinamide phosphoribosyltransferase activity)|go:""GO:0051770""(obsolete positive regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|rcsb pdb:6B76|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|rcsb pdb:7ENQ|rcsb pdb:7PPE|rcsb pdb:7PPF|rcsb pdb:7PPG|rcsb pdb:7PPH|rcsb pdb:7PPI|rcsb pdb:8DSC|rcsb pdb:8DSD|rcsb pdb:8DSE|rcsb pdb:8DSH|rcsb pdb:8DSI|rcsb pdb:8DSM|rcsb pdb:8DTJ|rcsb pdb:8F7L|rcsb pdb:8IVU|rcsb pdb:8TM7|reactome:R-HSA-1368108|reactome:R-HSA-197264|reactome:R-HSA-9768919|dip:DIP-29218N|panther:PTHR43816(orthology-group)"	"interpro:IPR001763(Rhodanese-like)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|refseq:WP_002210799.1|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0016784""(3-mercaptopyruvate sulfurtransferase activity)|interpro:IPR036873|refseq:YP_002346232.1|interpro:IPR045078|panther:PTHR11364(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606	rogid:tC9S/oaqk3d0afXfuawLwoksqPQ632	intact-crc:F3D690D3ED53830F|rigid:PSE0gCpxobyy53YTIRkVCzk3Vfk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C000	uniprotkb:A0A380PJJ5	intact:EBI-1220518|uniprotkb:Q9BZZ8|uniprotkb:Q9BZZ9|uniprotkb:Q9HAV8|uniprotkb:Q9UFT4|uniprotkb:Q9Y2E0|uniprotkb:E9PE50|uniprotkb:I6L9D9|uniprotkb:Q9H5Z7|uniprotkb:Q9H5Z8|ensembl:ENSP00000460475.1|ensembl:ENSP00000478516.1|ensembl:ENSP00000514534.1	intact:EBI-2845694|uniprotkb:Q0WI50|uniprotkb:Q7CGN7	psi-mi:nlrp1_human(display_long)|uniprotkb:NLRP1(gene name)|psi-mi:NLRP1(display_short)|uniprotkb:CARD7(gene name synonym)|uniprotkb:DEFCAP(gene name synonym)|uniprotkb:KIAA0926(gene name synonym)|uniprotkb:NAC(gene name synonym)|uniprotkb:NALP1(gene name synonym)|uniprotkb:Death effector filament-forming ced-4-like apoptosis protein(gene name synonym)|uniprotkb:Nucleotide-binding domain and caspase recruitment domain(gene name synonym)|uniprotkb:Caspase recruitment domain-containing protein 7(gene name synonym)	psi-mi:a0a380pjj5_yerpe(display_long)|uniprotkb:iucD(gene name)|psi-mi:iucD(display_short)|uniprotkb:YPO0993(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863668|imex:IM-13779-6891	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:352662""|ensembl:ENSG00000091592.17(gene)|ensembl:ENST00000572272.6(transcript)|ensembl:ENST00000617618.5(transcript)|ensembl:ENST00000699709.1(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0002221""(pattern recognition receptor signaling pathway)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0008233""(peptidase activity)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038187""(pattern recognition receptor activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051607""(defense response to virus)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0071493""(cellular response to UV-B)|go:""GO:0072558""(NLRP1 inflammasome complex)|go:""GO:0072559""(NLRP3 inflammasome complex)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097264""(self proteolysis)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140608""(cysteine-type endopeptidase activator activity)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1904784""(NLRP1 inflammasome complex assembly)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR004020(Pyrin)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|interpro:IPR027417|interpro:IPR032675|interpro:IPR033516|interpro:IPR041075|rcsb pdb:7WGE|interpro:IPR041267|interpro:IPR051249|mint:Q9C000|rcsb pdb:1PN5|rcsb pdb:3KAT|rcsb pdb:4IFP|rcsb pdb:4IM6|rcsb pdb:5Y3S|rcsb pdb:6K7V|rcsb pdb:6X6C|rcsb pdb:6XKK|rcsb pdb:8ZGD|reactome:R-HSA-844455|refseq:NP_001028225.1|refseq:NP_055737.1|refseq:NP_127497.1|refseq:NP_127499.1|refseq:NP_127500.1|dip:DIP-38407N|panther:PTHR46985(orthology-group)"	"interpro:IPR025700|refseq:WP_002211647.1|go:""GO:0047091""(""L-lysine 6-monooxygenase (NADPH) activity"")|interpro:IPR036188|refseq:YP_002346038.1|panther:PTHR42802(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tlXizUa/MP9AnLH5RpYPMcCB3UY9606	rogid:Yq7E3I4Gh8JvT7cRCoaBFJsJ5fU632	intact-crc:0D8C72606E20BFD6|rigid:a5w8/UrsGARQ9asK7GFPB6BKhZ8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UHE5	uniprotkb:Q8CWG4	intact:EBI-2863634|uniprotkb:O75839|uniprotkb:Q6LEU4|uniprotkb:Q96QI8|uniprotkb:Q9UQ17|ensembl:ENSP00000272425.3|ensembl:ENSP00000516938.1	intact:EBI-2856530|uniprotkb:Q74QZ9	psi-mi:nat8_human(display_long)|uniprotkb:NAT8(gene name)|psi-mi:NAT8(display_short)|uniprotkb:CML1(gene name synonym)|uniprotkb:GLA(gene name synonym)|uniprotkb:TSC501(gene name synonym)|uniprotkb:Camello-like protein 1(gene name synonym)|uniprotkb:Acetyltransferase 2(gene name synonym)|uniprotkb:Cysteinyl-conjugate N-acetyltransferase(gene name synonym)	psi-mi:q8cwg4_yerpe(display_long)|uniprotkb:glpD(gene name)|psi-mi:glpD(display_short)|uniprotkb:YP_3299(locus name)|uniprotkb:y3891(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863631|imex:IM-13779-6894	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003951.3|ensembl:ENSG00000144035.4(gene)|ensembl:ENSG00000291479.1(gene)|ensembl:ENST00000272425.4(transcript)|ensembl:ENST00000707634.1(transcript)|go:""GO:0004468""(L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0008080""(N-acetyltransferase activity)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0018003""(peptidyl-lysine N6-acetylation)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0047198""(L-cysteine-S-conjugate N-acetyltransferase activity)|go:""GO:1990000""(amyloid fibril formation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR050769|reactome:R-HSA-977225|panther:PTHR13947(orthology-group)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR031656|go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0006072""(glycerol-3-phosphate metabolic process)|go:""GO:0009331""(""glycerol-3-phosphate dehydrogenase (FAD) complex"")|interpro:IPR038299|interpro:IPR036188"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y8EPGgXOJF2+yt4jfZi9NTV8sQs9606	rogid:R9I22ZXVmXiKYYz/+NgwNjlHCb0632	intact-crc:680CDF8993D344E1|rigid:CJqv8HYPHyyoruEO9769j49lU3g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TBE9	uniprotkb:Q7ARD3	intact:EBI-2863646|uniprotkb:Q5JYN8|uniprotkb:Q9Y3N0|uniprotkb:Q8TE97|uniprotkb:B3KP12|ensembl:ENSP00000302441.3	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:nanp_human(display_long)|uniprotkb:NANP(gene name)|psi-mi:NANP(display_short)|uniprotkb:C20orf147(gene name synonym)|uniprotkb:HDHD4(gene name synonym)|uniprotkb:Haloacid dehalogenase-like hydrolase domain-containing protein 4(gene name synonym)|uniprotkb:Neu5Ac-9-Pase(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863654|imex:IM-13779-6890	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_689880.1|ensembl:ENSG00000170191.5(gene)|ensembl:ENST00000304788.4(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006045""(N-acetylglucosamine biosynthetic process)|go:""GO:0006055""(CMP-N-acetylneuraminate biosynthetic process)|go:""GO:0046380""(N-acetylneuraminate biosynthetic process)|go:""GO:0050124""(N-acylneuraminate-9-phosphatase activity)|go:""GO:0070085""(glycosylation)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR011950(HAD-superfamily hydrolase, subfamily IA, CTE7)|interpro:IPR023214|interpro:IPR036412|interpro:IPR051400|rcsb pdb:2W4M|rcsb pdb:4KNV|rcsb pdb:4KNW|reactome:R-HSA-4085001|panther:PTHR46470(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qNzet7NccYiV1oDPRfeFHTuFXRg9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:BF542015D49712AF|rigid:oYEOELLbe9TKb+bLnE2xDHK7KbE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86UW6	uniprotkb:A0A3N4BMJ4	intact:EBI-2804583|uniprotkb:Q9NVK2|uniprotkb:Q9P2D4|uniprotkb:A0AVR3|intact:EBI-28972272|ensembl:ENSP00000261435.6	intact:EBI-2842684|uniprotkb:Q74SI5|uniprotkb:Q7CJF7|uniprotkb:A0A0H2W631	psi-mi:n4bp2_human(display_long)|uniprotkb:B3BP(gene name synonym)|uniprotkb:KIAA1413(gene name synonym)|uniprotkb:BCL-3-binding protein(gene name synonym)|uniprotkb:N4BP2(gene name)|psi-mi:N4BP2(display_short)	psi-mi:a0a3n4bmj4_yerpe(display_long)|uniprotkb:ptsI(gene name)|psi-mi:ptsI(display_short)|uniprotkb:Phosphotransferase system, enzyme I(gene name synonym)|uniprotkb:YPO2994(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863724|imex:IM-13779-6899	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011512020.1|refseq:NP_060647.2|refseq:NP_001305288.1|refseq:XP_016863887.1|ensembl:ENSG00000078177.15(gene)|ensembl:ENST00000261435.11(transcript)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004520""(DNA endonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0046404""(ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity)|interpro:IPR002625(Smr protein/MutS2 C-terminal)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR013899(Region of unknown function DUF1771)|interpro:IPR027417|interpro:IPR036063|interpro:IPR041801|interpro:IPR052772|rcsb pdb:2D9I|rcsb pdb:2VKC|rcsb pdb:3BHB|rcsb pdb:3FAU|panther:PTHR46535(orthology-group)"	"interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR006318(Phosphoenolpyruvate-protein phosphotransferase)|interpro:IPR024692|interpro:IPR008731(Phosphotransferase system, PEP-utilising enzyme, N-terminal)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018274|interpro:IPR023151|go:""GO:0005737""(cytoplasm)|go:""GO:0008965""(phosphoenolpyruvate-protein phosphotransferase activity)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR040442|interpro:IPR036618|interpro:IPR036637|refseq:WP_002208490.1|refseq:YP_002347918.1|interpro:IPR050499|panther:PTHR46244(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SjG6xFHDSeW//hSDpVlz7DwdtrY9606	rogid:eLEHiZA3xPpbFGD5zpfuPDACip4632	intact-crc:5616EF559CE6BD9D|rigid:H27Ng73kxziqP8u72h4XDgeI1Kk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13506	uniprotkb:A0A3N4B6K1	intact:EBI-2863712|ensembl:ENSP00000336894.5|ensembl:ENSP00000387089.1|uniprotkb:Q9UEV1|uniprotkb:O75384|uniprotkb:Q6GTU1|uniprotkb:O75383	intact:EBI-2841967|uniprotkb:Q7CHV2|uniprotkb:Q0WG31	psi-mi:nab1_human(display_long)|uniprotkb:NAB1(gene name)|psi-mi:NAB1(display_short)|uniprotkb:EGR-1-binding protein 1(gene name synonym)|uniprotkb:Transcriptional regulatory protein p54(gene name synonym)	psi-mi:a0a3n4b6k1_yerpe(display_long)|uniprotkb:EIIAB-Man(gene name synonym)|uniprotkb:gptB(gene name)|psi-mi:gptB(display_short)|uniprotkb:EIII-Man(gene name synonym)|uniprotkb:manX(gene name synonym)|uniprotkb:ptsL(gene name synonym)|uniprotkb:YPO1758(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863709|imex:IM-13779-6897	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011509521.1|ensembl:ENSG00000138386.17(gene)|ensembl:ENST00000337386.10(transcript)|ensembl:ENST00000409581.5(transcript)|go:""GO:0001958""(endochondral ossification)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0014037""(Schwann cell differentiation)|go:""GO:0042552""(myelination)|go:""GO:0045682""(regulation of epidermis development)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR006986(Nab1, C-terminal)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR006989(Nab, central region)|interpro:IPR038398|interpro:IPR039040|rcsb pdb:2YUF|reactome:R-HSA-9031628|reactome:R-HSA-9619665|refseq:NP_005957.2|refseq:XP_016859659.1|refseq:XP_016859665.1|refseq:XP_005246639.1|refseq:XP_005246640.1|refseq:NP_001308241.1|refseq:NP_001308242.1|refseq:NP_001308243.1|refseq:NP_001308244.1|panther:PTHR12623(orthology-group)"	"interpro:IPR004701(Phosphotransferase system, fructose subfamily IIA component)|interpro:IPR013789(Phosphotransferase system, fructose subfamily IIA component, subgroup)|interpro:IPR004720(Phosphotransferase system, sorbose subfamily IIB component)|interpro:IPR018455|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|interpro:IPR033887|interpro:IPR036662|interpro:IPR036667|refseq:WP_002211069.1|refseq:YP_002346757.1|interpro:IPR051471|panther:PTHR33799(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NfG5F48HahujhxoiPrOOURhtBn89606	rogid:6EMnus36OolbaozHpfdN+4jAtF0632	intact-crc:059C46BF41914CC1|rigid:LMrxEwJfyb0OasHeAuOQkn42cqg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UJ70	uniprotkb:Q9ZC68	intact:EBI-372578|uniprotkb:Q53HD5|uniprotkb:Q6IA84|uniprotkb:Q9BVP0|uniprotkb:Q9NV37|uniprotkb:Q9BS29|ensembl:ENSP00000244204.5|uniprotkb:B4DLZ5	intact:EBI-2843867|uniprotkb:Q7CI72|uniprotkb:Q74UK4	psi-mi:nagk_human(display_long)|uniprotkb:GlcNAc kinase(gene name synonym)|uniprotkb:NAGK(gene name)|psi-mi:NAGK(display_short)|uniprotkb:Muramyl dipeptide kinase(gene name synonym)|uniprotkb:N-acetyl-D-mannosamine kinase(gene name synonym)	psi-mi:astd_yerpe(display_long)|uniprotkb:astD(gene name)|psi-mi:astD(display_short)|uniprotkb:Succinylglutamic semialdehyde dehydrogenase(gene name synonym)|uniprotkb:YPO1964(locus name)|uniprotkb:y2347(locus name)|uniprotkb:YP_1709(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863702|imex:IM-13779-6896	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000124357.13(gene)|ensembl:ENST00000244204.11(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006044""(N-acetylglucosamine metabolic process)|go:""GO:0006046""(N-acetylglucosamine catabolic process)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0006051""(N-acetylmannosamine metabolic process)|go:""GO:0019262""(N-acetylneuraminate catabolic process)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045087""(innate immune response)|go:""GO:0045127""(N-acetylglucosamine kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070434""(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0160047""(muramyl dipeptide kinase activity)|interpro:IPR002731(ATPase, BadF/BadG/BcrA/BcrD type)|interpro:IPR039758|interpro:IPR043129|mint:Q9UJ70|rcsb pdb:2CH5|rcsb pdb:2CH6|reactome:R-HSA-446210|refseq:NP_060037.3|panther:PTHR12862(orthology-group)"	"refseq:WP_002212030.1|interpro:IPR029510|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR017649(Succinylglutamic semialdehyde dehydrogenase)|go:""GO:0019544""(arginine catabolic process to glutamate)|go:""GO:0019545""(arginine catabolic process to succinate)|go:""GO:0043824""(succinylglutamate-semialdehyde dehydrogenase activity)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:YP_002346953.1|panther:PTHR11699(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ao/nyOFgPuF6H39ubvyWeOQv7sM9606	rogid:lAw8pbIH2i1IjXZl8H7zAJvQj0I632	intact-crc:2632315C1124AC74|rigid:qNakEaEfQ1BhvGAdD3lkyRXek14	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UJ70	uniprotkb:Q8ZBM5	intact:EBI-372578|uniprotkb:Q53HD5|uniprotkb:Q6IA84|uniprotkb:Q9BVP0|uniprotkb:Q9NV37|uniprotkb:Q9BS29|ensembl:ENSP00000244204.5|uniprotkb:B4DLZ5	intact:EBI-2843506|uniprotkb:Q0WBR3	psi-mi:nagk_human(display_long)|uniprotkb:GlcNAc kinase(gene name synonym)|uniprotkb:NAGK(gene name)|psi-mi:NAGK(display_short)|uniprotkb:Muramyl dipeptide kinase(gene name synonym)|uniprotkb:N-acetyl-D-mannosamine kinase(gene name synonym)	psi-mi:dgtp_yerpe(display_long)|uniprotkb:dgt(gene name)|psi-mi:dgt(display_short)|uniprotkb:YPO3383(locus name)|uniprotkb:y0806(locus name)|uniprotkb:YP_0302(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863695|imex:IM-13779-6898	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000124357.13(gene)|ensembl:ENST00000244204.11(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006044""(N-acetylglucosamine metabolic process)|go:""GO:0006046""(N-acetylglucosamine catabolic process)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0006051""(N-acetylmannosamine metabolic process)|go:""GO:0019262""(N-acetylneuraminate catabolic process)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045087""(innate immune response)|go:""GO:0045127""(N-acetylglucosamine kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070434""(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0160047""(muramyl dipeptide kinase activity)|interpro:IPR002731(ATPase, BadF/BadG/BcrA/BcrD type)|interpro:IPR039758|interpro:IPR043129|mint:Q9UJ70|rcsb pdb:2CH5|rcsb pdb:2CH6|reactome:R-HSA-446210|refseq:NP_060037.3|panther:PTHR12862(orthology-group)"	"interpro:IPR006261(Deoxyguanosinetriphosphate triphosphohydrolase)|interpro:IPR023293|interpro:IPR020779|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR026875|go:""GO:0000287""(magnesium ion binding)|go:""GO:0006203""(dGTP catabolic process)|go:""GO:0008832""(dGTPase activity)|refseq:WP_002209369.1|refseq:YP_002348275.1|interpro:IPR050135|panther:PTHR11373(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ao/nyOFgPuF6H39ubvyWeOQv7sM9606	rogid:W9U0OTGxW9YIGgAtcpzcULXNA2M632	intact-crc:4CD8908163FCA7AC|rigid:e97mSKuNmgXcOB2qmhHyecSZ2j4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GY68	uniprotkb:Q9Y3Q0	intact:EBI-2847839|uniprotkb:A0A5P8YCG4|uniprotkb:Q74X57|uniprotkb:A0A0H2W1S5|uniprotkb:Q7CKH8|uniprotkb:A0A384K818	intact:EBI-2863682|uniprotkb:Q4VAM9|uniprotkb:B3KQR4|uniprotkb:Q4KKV4|ensembl:ENSP00000432481.1|ensembl:ENSP00000494766.1	psi-mi:a0a2u2gy68_yerpe(display_long)|uniprotkb:ibeB(gene name)|psi-mi:ibeB(display_short)|uniprotkb:YPO3481(locus name)	psi-mi:nald2_human(display_long)|uniprotkb:NAALAD2(gene name)|psi-mi:NAALAD2(display_short)|uniprotkb:N-acetylated-alpha-linked acidic dipeptidase II(gene name synonym)|uniprotkb:Glutamate carboxypeptidase III(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863688|imex:IM-13779-6895	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003423(Outer membrane efflux protein)|interpro:IPR010131(RND efflux system, outer membrane lipoprotein, NodT)|refseq:WP_002209268.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015562""(efflux transmembrane transporter activity)|refseq:YP_002348370.1|interpro:IPR050737"	"refseq:NP_005458.1|refseq:NP_001287859.1|ensembl:ENSG00000077616.11(gene)|ensembl:ENSG00000285516.2(gene)|ensembl:ENST00000534061.6(transcript)|ensembl:ENST00000647397.2(transcript)|go:""GO:0004180""(carboxypeptidase activity)|go:""GO:0004181""(metallocarboxypeptidase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008239""(dipeptidyl-peptidase activity)|go:""GO:0016020""(membrane)|go:""GO:0016805""(dipeptidase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR039373|interpro:IPR046450|rcsb pdb:3FEC|rcsb pdb:3FED|rcsb pdb:3FEE|rcsb pdb:3FF3|reactome:R-HSA-8963693|panther:PTHR10404(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3YSC2/pysIcDgc2iQ5Hs9cZX3oU632	rogid:GD0oRig0JtWjhrRa0GvW9nSI6F49606	intact-crc:235709D075167EDD|rigid:GLhL2D6MgV1+n1ZV+tvjBPZYm0s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W6D0	uniprotkb:Q5VU43	intact:EBI-2862004|uniprotkb:Q74SF8|uniprotkb:Q0WCP0|uniprotkb:Q7CJH7|uniprotkb:A0A454XVI6|uniprotkb:A0A384KIW1	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360.3|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:a0a0h2w6d0_yerpe(display_long)|uniprotkb:YPO3028(locus name)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863745|imex:IM-13779-6903	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)|refseq:WP_002208523.1|interpro:IPR051551|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0009279""(cell outer membrane)|interpro:IPR036709|refseq:YP_002347948.1"	"refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|ensembl:ENSG00000178104.22(gene)|ensembl:ENST00000369354.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0007098""(centrosome cycle)|go:""GO:0019899""(enzyme binding)|go:""GO:0030016""(myofibril)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|interpro:IPR052593|mint:Q5VU43|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|panther:PTHR46501(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:W2gvcG57x1Q5nQ5vtCMffIM1uB8632	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	intact-crc:6C0FE174B0F92BB7|rigid:1HoRT98D4xYUnX2REczvg5vKT8Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15746	uniprotkb:A0A5P8YEX9	intact:EBI-968482|intact:EBI-28987351|uniprotkb:O95796|uniprotkb:O95797|uniprotkb:O95798|uniprotkb:O95799|uniprotkb:Q14844|uniprotkb:Q16794|uniprotkb:Q5MY99|uniprotkb:Q5MYA0|intact:EBI-1758586|uniprotkb:B4DUE3|uniprotkb:D3DN97|uniprotkb:Q17S15|uniprotkb:Q6P2N0|uniprotkb:Q7Z4J0|uniprotkb:Q9C0L5|uniprotkb:Q9UBG5|uniprotkb:Q9UIT9|intact:EBI-1963605|uniprotkb:Q3ZCP9|uniprotkb:Q9UBY6|ensembl:ENSP00000353452.3|ensembl:ENSP00000508758.1	intact:EBI-2863752	psi-mi:mylk_human(display_long)|uniprotkb:MYLK(gene name)|psi-mi:MYLK(display_short)|uniprotkb:MLCK(gene name synonym)|uniprotkb:Telokin(gene name synonym)|uniprotkb:Kinase-related protein(gene name synonym)|uniprotkb:MLCK1(gene name synonym)|uniprotkb:MYLK1(gene name synonym)	psi-mi:a0a5p8yex9_yerpe(display_long)|uniprotkb:NCTC5923_03924(orf name)|uniprotkb:YP_1873(locus name)|uniprotkb:y2281(locus name)|uniprotkb:tbpA1(gene name)|psi-mi:tbpA1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863757|imex:IM-13779-6901	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2241""|efo:""Orphanet:91387""|ensembl:ENSG00000065534.20(gene)|ensembl:ENST00000360304.8(transcript)|ensembl:ENST00000686761.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0004687""(myosin light chain kinase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006939""(smooth muscle contraction)|go:""GO:0014820""(tonic smooth muscle contraction)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032060""(bleb assembly)|go:""GO:0032154""(cleavage furrow)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0071476""(cellular hypotonic response)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097110""(scaffold protein binding)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015725(Myosin Light Chain Kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036116|interpro:IPR036179|mint:Q15746|rcsb pdb:2CQV|rcsb pdb:2K0F|rcsb pdb:2YR3|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:6C6M|reactome:R-HSA-445355|reactome:R-HSA-5627123|refseq:NP_001308238.1|refseq:NP_444253.3|refseq:NP_444254.3|refseq:NP_444255.3|refseq:NP_444256.3|refseq:NP_444259.1|refseq:NP_444260.1|refseq:XP_011511162.1|refseq:XP_016861958.1|refseq:XP_016861960.1|refseq:XP_016861961.1|refseq:XP_016861962.1|panther:PTHR47633(orthology-group)"	"go:""GO:0030313""(cell envelope)|uniprotkb:A0A0H2W3U0(uniprot-removed-ac)|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|refseq:WP_002211228.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Wm0QbKY5KOVPytbFu5NCcT0Z1ek9606	rogid:nCVr4ofzqqbhmeSvmI+A9uiA/8o632	intact-crc:B6ACFB407CC420D2|rigid:JqRUaVq9vtJ/BFNSRjwJclf2ELM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZQ9	uniprotkb:Q15746	intact:EBI-2852846|uniprotkb:Q74RW8	intact:EBI-968482|intact:EBI-28987351|uniprotkb:O95796|uniprotkb:O95797|uniprotkb:O95798|uniprotkb:O95799|uniprotkb:Q14844|uniprotkb:Q16794|uniprotkb:Q5MY99|uniprotkb:Q5MYA0|intact:EBI-1758586|uniprotkb:B4DUE3|uniprotkb:D3DN97|uniprotkb:Q17S15|uniprotkb:Q6P2N0|uniprotkb:Q7Z4J0|uniprotkb:Q9C0L5|uniprotkb:Q9UBG5|uniprotkb:Q9UIT9|intact:EBI-1963605|uniprotkb:Q3ZCP9|uniprotkb:Q9UBY6|ensembl:ENSP00000353452.3|ensembl:ENSP00000508758.1	psi-mi:q8czq9_yerpe(display_long)|uniprotkb:y3602(locus name)|uniprotkb:exuR(gene name)|psi-mi:exuR(display_short)|uniprotkb:YP_2896(locus name)	psi-mi:mylk_human(display_long)|uniprotkb:MYLK(gene name)|psi-mi:MYLK(display_short)|uniprotkb:MLCK(gene name synonym)|uniprotkb:Telokin(gene name synonym)|uniprotkb:Kinase-related protein(gene name synonym)|uniprotkb:MLCK1(gene name synonym)|uniprotkb:MYLK1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863764|imex:IM-13779-6902	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011711(GntR, C-terminal)|interpro:IPR000524(Bacterial regulatory protein GntR, HTH)|interpro:IPR008920(Fatty acid responsive transcription factor FadR, C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390"	"efo:""Orphanet:2241""|efo:""Orphanet:91387""|ensembl:ENSG00000065534.20(gene)|ensembl:ENST00000360304.8(transcript)|ensembl:ENST00000686761.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0004687""(myosin light chain kinase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006939""(smooth muscle contraction)|go:""GO:0014820""(tonic smooth muscle contraction)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032060""(bleb assembly)|go:""GO:0032154""(cleavage furrow)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0071476""(cellular hypotonic response)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097110""(scaffold protein binding)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015725(Myosin Light Chain Kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036116|interpro:IPR036179|mint:Q15746|rcsb pdb:2CQV|rcsb pdb:2K0F|rcsb pdb:2YR3|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:6C6M|reactome:R-HSA-445355|reactome:R-HSA-5627123|refseq:NP_001308238.1|refseq:NP_444253.3|refseq:NP_444254.3|refseq:NP_444255.3|refseq:NP_444256.3|refseq:NP_444259.1|refseq:NP_444260.1|refseq:XP_011511162.1|refseq:XP_016861958.1|refseq:XP_016861960.1|refseq:XP_016861961.1|refseq:XP_016861962.1|panther:PTHR47633(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RD2sxgq5tm9YnJVsIx4EdMD3/Uw632	rogid:Wm0QbKY5KOVPytbFu5NCcT0Z1ek9606	intact-crc:9EE025D6B24EA4C4|rigid:7uc3Eylldc/AetW9OwwlJfNhqXE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WYB5	uniprotkb:A0A6M0NII6	intact:EBI-948029|uniprotkb:O15087|uniprotkb:Q86Y05|uniprotkb:Q8WU81|uniprotkb:Q9UKW2|uniprotkb:Q9UKW3|uniprotkb:Q9UKX0|ensembl:ENSP00000287239.4|ensembl:ENSP00000486595.1|ensembl:ENSP00000497166.1|ensembl:ENSP00000497352.1|ensembl:ENSP00000497718.1|ensembl:ENSP00000497841.1	intact:EBI-2841704	psi-mi:kat6b_human(display_long)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4(gene name synonym)|uniprotkb:Histone acetyltransferase MOZ2(gene name synonym)|uniprotkb:Monocytic leukemia zinc finger protein-related factor(gene name synonym)|uniprotkb:KAT6B(gene name)|psi-mi:KAT6B(display_short)|uniprotkb:MYST4(gene name synonym)|uniprotkb:KIAA0383(gene name synonym)|uniprotkb:MORF(gene name synonym)|uniprotkb:MOZ2(gene name synonym)	psi-mi:a0a6m0nii6_yerpe(display_long)|uniprotkb:y2471(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863731|imex:IM-13779-6904	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:3047""|efo:""Orphanet:85201""|ensembl:ENSG00000156650.14(gene)|ensembl:ENSG00000281813.4(gene)|ensembl:ENST00000287239.10(transcript)|ensembl:ENST00000630001.4(transcript)|ensembl:ENST00000647630.1(transcript)|ensembl:ENST00000648605.1(transcript)|ensembl:ENST00000648725.1(transcript)|ensembl:ENST00000649463.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000786""(nucleosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010484""(histone H3 acetyltransferase activity)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0050793""(regulation of developmental process)|go:""GO:0061733""(protein-lysine-acetyltransferase activity)|go:""GO:0070776""(MOZ/MORF histone acetyltransferase complex)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1903706""(regulation of hemopoiesis)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR005818(Histone H1/H5)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR019787|interpro:IPR036388|interpro:IPR036390|interpro:IPR040706|interpro:IPR048589|interpro:IPR050603|mint:Q8WYB5|rcsb pdb:5U2J|rcsb pdb:6OIE|rcsb pdb:8E4V|reactome:R-HSA-3214847|refseq:NP_001243397.1|refseq:NP_001243398.1|refseq:NP_036462.2|refseq:XP_005269721.1|refseq:XP_016871489.1|refseq:XP_016871490.1|refseq:XP_016871491.1|refseq:XP_016871492.1|refseq:XP_016871494.1|refseq:XP_016871495.1|refseq:XP_016871496.1|refseq:XP_016871497.1|panther:PTHR10615(orthology-group)"	"uniprotkb:A0A6B3T0M9(uniprot-removed-ac)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR029016|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|refseq:WP_002228541.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SQZ29f1Wqak9s8f4A1mrKmfToU09606	rogid:d/mBSOpThH3MO4/Ze3GAgpPOK+o632	intact-crc:E1657D1599FA259E|rigid:MI1EEpylKZYfDpOsG5iXUCUwtRs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P58543	uniprotkb:Q9NPC6	intact:EBI-2847390|uniprotkb:Q0WER7	intact:EBI-746712|ensembl:ENSP00000306997.6|uniprotkb:O43415|uniprotkb:Q9HB92	psi-mi:arab_yerpe(display_long)|uniprotkb:araB(gene name)|psi-mi:araB(display_short)|uniprotkb:YPO2254(locus name)|uniprotkb:y2095(locus name)|uniprotkb:YP_2050(locus name)	psi-mi:myoz2_human(display_long)|uniprotkb:Calsarcin-1(gene name synonym)|uniprotkb:FATZ-related protein 2(gene name synonym)|uniprotkb:MYOZ2(gene name)|psi-mi:MYOZ2(display_short)|uniprotkb:C4orf5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863738|imex:IM-13779-6900	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018485|interpro:IPR005929(L-ribulokinase)|interpro:IPR043129|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008741""(ribulokinase activity)|go:""GO:0019150""(D-ribulokinase activity)|go:""GO:0019321""(pentose metabolic process)|go:""GO:0019569""(L-arabinose catabolic process to xylulose 5-phosphate)|refseq:YP_002347221.1|panther:PTHR43435(orthology-group)"	"ensembl:ENSG00000172399.6(gene)|ensembl:ENST00000307128.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003779""(actin binding)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030017""(sarcomere)|go:""GO:0030018""(Z disc)|go:""GO:0030346""(protein phosphatase 2B binding)|go:""GO:0031433""(telethonin binding)|go:""GO:0043503""(skeletal muscle fiber adaptation)|go:""GO:0045214""(sarcomere organization)|go:""GO:0051373""(FATZ binding)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR008438(Calcineurin-binding)|refseq:NP_057683.1|panther:PTHR15941(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hejpPk7Q+tUU+cmG5v4jTehB47I632	rogid:Y2B5tDM2oGscI8xiTwB69hFEhL89606	intact-crc:31BEE23DD4812DE8|rigid:HStxstybgx8sMotUf+UkmOZRBRE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PJE2	uniprotkb:Q15746	intact:EBI-2850829|uniprotkb:Q74WU5|uniprotkb:Q0WC89|uniprotkb:Q7CK47|uniprotkb:A0A384L2F1	intact:EBI-968482|intact:EBI-28987351|uniprotkb:O95796|uniprotkb:O95797|uniprotkb:O95798|uniprotkb:O95799|uniprotkb:Q14844|uniprotkb:Q16794|uniprotkb:Q5MY99|uniprotkb:Q5MYA0|intact:EBI-1758586|uniprotkb:B4DUE3|uniprotkb:D3DN97|uniprotkb:Q17S15|uniprotkb:Q6P2N0|uniprotkb:Q7Z4J0|uniprotkb:Q9C0L5|uniprotkb:Q9UBG5|uniprotkb:Q9UIT9|intact:EBI-1963605|uniprotkb:Q3ZCP9|uniprotkb:Q9UBY6|ensembl:ENSP00000353452.3|ensembl:ENSP00000508758.1	psi-mi:a0a2s9pje2_yerpe(display_long)|uniprotkb:ahpC(gene name)|psi-mi:ahpC(display_short)|uniprotkb:YPO3194(locus name)	psi-mi:mylk_human(display_long)|uniprotkb:MYLK(gene name)|psi-mi:MYLK(display_short)|uniprotkb:MLCK(gene name synonym)|uniprotkb:Telokin(gene name synonym)|uniprotkb:Kinase-related protein(gene name synonym)|uniprotkb:MLCK1(gene name synonym)|uniprotkb:MYLK1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863771|imex:IM-13779-6905	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013766(Thioredoxin domain)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|refseq:WP_002208675.1|go:""GO:0005829""(cytosol)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0045454""(cell redox homeostasis)|interpro:IPR036249|refseq:YP_002348099.1|interpro:IPR050217|panther:PTHR10681(orthology-group)"	"efo:""Orphanet:2241""|efo:""Orphanet:91387""|ensembl:ENSG00000065534.20(gene)|ensembl:ENST00000360304.8(transcript)|ensembl:ENST00000686761.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0004687""(myosin light chain kinase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006939""(smooth muscle contraction)|go:""GO:0014820""(tonic smooth muscle contraction)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032060""(bleb assembly)|go:""GO:0032154""(cleavage furrow)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0071476""(cellular hypotonic response)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097110""(scaffold protein binding)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015725(Myosin Light Chain Kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036116|interpro:IPR036179|mint:Q15746|rcsb pdb:2CQV|rcsb pdb:2K0F|rcsb pdb:2YR3|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:6C6M|reactome:R-HSA-445355|reactome:R-HSA-5627123|refseq:NP_001308238.1|refseq:NP_444253.3|refseq:NP_444254.3|refseq:NP_444255.3|refseq:NP_444256.3|refseq:NP_444259.1|refseq:NP_444260.1|refseq:XP_011511162.1|refseq:XP_016861958.1|refseq:XP_016861960.1|refseq:XP_016861961.1|refseq:XP_016861962.1|panther:PTHR47633(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GnZEc/ZzTTpq4nrPnH46z4CNIwg632	rogid:Wm0QbKY5KOVPytbFu5NCcT0Z1ek9606	intact-crc:8084A1A0CE55D25F|rigid:X9XH9mX19GcYu2ZBTE+boYdvywI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35579	uniprotkb:Q9RIC3	intact:EBI-350338|uniprotkb:O60805|uniprotkb:Q86T83|intact:EBI-1054343|intact:EBI-25631636|uniprotkb:A8K6E4|uniprotkb:Q60FE2|ensembl:ENSP00000216181.6	intact:EBI-56885267|uniprotkb:Q7BTT1	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:q9ric3_yerpe(display_long)|uniprotkb:ymt(gene name)|psi-mi:ymt(display_short)|uniprotkb:tox(gene name synonym)|uniprotkb:YPMT1.74(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863799|imex:IM-13779-6909	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:182050""|efo:""Orphanet:477742""|efo:""Orphanet:90635""|ensembl:ENSG00000100345.23(gene)|ensembl:ENST00000216181.11(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000212""(meiotic spindle organization)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0001931""(uropod)|go:""GO:0003723""(RNA binding)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005826""(actomyosin contractile ring)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016604""(nuclear body)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030220""(platelet formation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032418""(lysosome localization)|go:""GO:0032506""(cytokinetic process)|go:""GO:0032796""(uropod organization)|go:""GO:0032982""(myosin filament)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042641""(actomyosin)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043531""(ADP binding)|go:""GO:0043534""(blood vessel endothelial cell migration)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051015""(actin filament binding)|go:""GO:0051295""(establishment of meiotic spindle localization)|go:""GO:0060471""(cortical granule exocytosis)|go:""GO:0060473""(cortical granule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097513""(myosin II filament)|go:""GO:1903919""(negative regulation of actin filament severing)|go:""GO:1903923""(positive regulation of protein processing in phagocytic vesicle)|go:""GO:1905684""(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|reactome:R-HSA-9725370|refseq:NP_002464.1|refseq:XP_011528499.1|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|panther:PTHR45615(orthology-group)"	"refseq:NP_395420.2|refseq:NP_857705.3|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|go:""GO:0008808""(cardiolipin synthase activity)|go:""GO:0016020""(membrane)|go:""GO:0032049""(cardiolipin biosynthetic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	rogid:/8mxO/sUbVPkh1AMeB0FLnlkNWY632	intact-crc:C10EBE885DA6A62C|rigid:Wf2V8mRYImeB1xw0rq9nKt/bG/c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CIA2	uniprotkb:P60660	intact:EBI-2849892|uniprotkb:Q74U75	intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9|ensembl:ENSP00000446955.2|ensembl:ENSP00000448101.1	"psi-mi:prmc_yerpe(display_long)|uniprotkb:N5-glutamine methyltransferase PrmC(gene name synonym)|uniprotkb:""Protein-(glutamine-N5) MTase PrmC""(gene name synonym)|uniprotkb:Protein-glutamine N-methyltransferase PrmC(gene name synonym)|uniprotkb:hemK(gene name synonym)|uniprotkb:YPO2018(locus name)|uniprotkb:YP_1866(locus name)|uniprotkb:y2289(locus name)|uniprotkb:prmC(gene name)|psi-mi:prmC(display_short)"	psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863792|imex:IM-13779-6907	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004556(Modification methylase HemK)|interpro:IPR019874|interpro:IPR025714|interpro:IPR029063|refseq:WP_002211235.1|interpro:IPR040758|go:""GO:0003676""(nucleic acid binding)|go:""GO:0006415""(translational termination)|go:""GO:0032259""(methylation)|go:""GO:0036009""(protein-glutamine N-methyltransferase activity)|go:""GO:0102559""(""peptide chain release factor N(5)-glutamine methyltransferase activity"")|refseq:YP_002347004.1|interpro:IPR050320|panther:PTHR18895(orthology-group)"	"refseq:NP_066299.2|refseq:NP_524147.2|ensembl:ENSG00000092841.19(gene)|ensembl:ENST00000548293.5(transcript)|ensembl:ENST00000550697.6(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0006936""(muscle contraction)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0016020""(membrane)|go:""GO:0016459""(myosin complex)|go:""GO:0016460""(myosin II complex)|go:""GO:0016461""(unconventional myosin complex)|go:""GO:0030049""(muscle filament sliding)|go:""GO:0031982""(vesicle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR050230|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|panther:PTHR23048(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:THdPGJ4n/c8dQ78xq18i7nKkalc632	rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606	intact-crc:F2D40CDC332FF7A5|rigid:5KeQK6l6CLAC5U/KGWtevxFWiwI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15746	uniprotkb:A0A380PFG3	intact:EBI-968482|intact:EBI-28987351|uniprotkb:O95796|uniprotkb:O95797|uniprotkb:O95798|uniprotkb:O95799|uniprotkb:Q14844|uniprotkb:Q16794|uniprotkb:Q5MY99|uniprotkb:Q5MYA0|intact:EBI-1758586|uniprotkb:B4DUE3|uniprotkb:D3DN97|uniprotkb:Q17S15|uniprotkb:Q6P2N0|uniprotkb:Q7Z4J0|uniprotkb:Q9C0L5|uniprotkb:Q9UBG5|uniprotkb:Q9UIT9|intact:EBI-1963605|uniprotkb:Q3ZCP9|uniprotkb:Q9UBY6|ensembl:ENSP00000353452.3|ensembl:ENSP00000508758.1	intact:EBI-2844399|uniprotkb:Q0WCT9|uniprotkb:Q7CJE7	psi-mi:mylk_human(display_long)|uniprotkb:MYLK(gene name)|psi-mi:MYLK(display_short)|uniprotkb:MLCK(gene name synonym)|uniprotkb:Telokin(gene name synonym)|uniprotkb:Kinase-related protein(gene name synonym)|uniprotkb:MLCK1(gene name synonym)|uniprotkb:MYLK1(gene name synonym)	psi-mi:a0a380pfg3_yerpe(display_long)|uniprotkb:YPO2975(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863778|imex:IM-13779-6908	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2241""|efo:""Orphanet:91387""|ensembl:ENSG00000065534.20(gene)|ensembl:ENST00000360304.8(transcript)|ensembl:ENST00000686761.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0004687""(myosin light chain kinase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006939""(smooth muscle contraction)|go:""GO:0014820""(tonic smooth muscle contraction)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032060""(bleb assembly)|go:""GO:0032154""(cleavage furrow)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0071476""(cellular hypotonic response)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097110""(scaffold protein binding)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015725(Myosin Light Chain Kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036116|interpro:IPR036179|mint:Q15746|rcsb pdb:2CQV|rcsb pdb:2K0F|rcsb pdb:2YR3|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:6C6M|reactome:R-HSA-445355|reactome:R-HSA-5627123|refseq:NP_001308238.1|refseq:NP_444253.3|refseq:NP_444254.3|refseq:NP_444255.3|refseq:NP_444256.3|refseq:NP_444259.1|refseq:NP_444260.1|refseq:XP_011511162.1|refseq:XP_016861958.1|refseq:XP_016861960.1|refseq:XP_016861961.1|refseq:XP_016861962.1|panther:PTHR47633(orthology-group)"	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002211613.1|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:YP_002347899.1|interpro:IPR050881|panther:PTHR42832(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Wm0QbKY5KOVPytbFu5NCcT0Z1ek9606	rogid:gxs4oIww4YLZ4JkmmT+hmD0ULQM632	intact-crc:A5972534E7016457|rigid:Jlu3BN7MClaAOtILYia0jAyWmEc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15746	uniprotkb:Q7ARD3	intact:EBI-968482|intact:EBI-28987351|uniprotkb:O95796|uniprotkb:O95797|uniprotkb:O95798|uniprotkb:O95799|uniprotkb:Q14844|uniprotkb:Q16794|uniprotkb:Q5MY99|uniprotkb:Q5MYA0|intact:EBI-1758586|uniprotkb:B4DUE3|uniprotkb:D3DN97|uniprotkb:Q17S15|uniprotkb:Q6P2N0|uniprotkb:Q7Z4J0|uniprotkb:Q9C0L5|uniprotkb:Q9UBG5|uniprotkb:Q9UIT9|intact:EBI-1963605|uniprotkb:Q3ZCP9|uniprotkb:Q9UBY6|ensembl:ENSP00000353452.3|ensembl:ENSP00000508758.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:mylk_human(display_long)|uniprotkb:MYLK(gene name)|psi-mi:MYLK(display_short)|uniprotkb:MLCK(gene name synonym)|uniprotkb:Telokin(gene name synonym)|uniprotkb:Kinase-related protein(gene name synonym)|uniprotkb:MLCK1(gene name synonym)|uniprotkb:MYLK1(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863785|imex:IM-13779-6906	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2241""|efo:""Orphanet:91387""|ensembl:ENSG00000065534.20(gene)|ensembl:ENST00000360304.8(transcript)|ensembl:ENST00000686761.1(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0004687""(myosin light chain kinase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006939""(smooth muscle contraction)|go:""GO:0014820""(tonic smooth muscle contraction)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032060""(bleb assembly)|go:""GO:0032154""(cleavage furrow)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|go:""GO:0051928""(positive regulation of calcium ion transport)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0071476""(cellular hypotonic response)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097110""(scaffold protein binding)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015725(Myosin Light Chain Kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036116|interpro:IPR036179|mint:Q15746|rcsb pdb:2CQV|rcsb pdb:2K0F|rcsb pdb:2YR3|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:6C6M|reactome:R-HSA-445355|reactome:R-HSA-5627123|refseq:NP_001308238.1|refseq:NP_444253.3|refseq:NP_444254.3|refseq:NP_444255.3|refseq:NP_444256.3|refseq:NP_444259.1|refseq:NP_444260.1|refseq:XP_011511162.1|refseq:XP_016861958.1|refseq:XP_016861960.1|refseq:XP_016861961.1|refseq:XP_016861962.1|panther:PTHR47633(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Wm0QbKY5KOVPytbFu5NCcT0Z1ek9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:A69FA3CD6F1443EF|rigid:auYaN7YRBuXoM3wtvJZXEm+3qy4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1P8	uniprotkb:Q8N699	intact:EBI-2841883	intact:EBI-2804634|uniprotkb:Q9H763|uniprotkb:Q8N396|uniprotkb:Q8TBE8|ensembl:ENSP00000356214.5	psi-mi:q8d1p8_yerpe(display_long)|uniprotkb:tcaA1(gene name)|psi-mi:tcaA1(display_short)|uniprotkb:y0183(locus name)	psi-mi:myct1_human(display_long)|uniprotkb:MTLC(gene name synonym)|uniprotkb:MTMC1(gene name synonym)|uniprotkb:Myc target in myeloid cells protein 1(gene name synonym)|uniprotkb:MYCT1(gene name)|psi-mi:MYCT1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863820|imex:IM-13779-6913	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR018003	"refseq:XP_011534451.1|refseq:XP_011534452.1|refseq:XP_011534453.1|refseq:XP_011534454.1|refseq:NP_079383.2|ensembl:ENSG00000120279.7(gene)|ensembl:ENST00000367245.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016604""(nuclear body)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|interpro:IPR029180|mint:Q8N699|refseq:XP_016866808.1|panther:PTHR14869(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LfA2Lz71pTe9HDOA0UOS0/RgEsY632	rogid:/ppiWzZNtf2iURw/XIZ7ujOyIlQ9606	intact-crc:800559585536AD45|rigid:GlMD5mqoz9xPy+zQED42T4JbdZc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35579	uniprotkb:Q8ZFB2	intact:EBI-350338|uniprotkb:O60805|uniprotkb:Q86T83|intact:EBI-1054343|intact:EBI-25631636|uniprotkb:A8K6E4|uniprotkb:Q60FE2|ensembl:ENSP00000216181.6	intact:EBI-2842002|uniprotkb:Q0WFY8|uniprotkb:Q8CWH3|uniprotkb:Q74UV7	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:flgh2_yerpe(display_long)|uniprotkb:flgH2(gene name)|psi-mi:flgH2(display_short)|uniprotkb:Basal body L-ring protein 2(gene name synonym)|uniprotkb:YPO1805(locus name)|uniprotkb:y2504(locus name)|uniprotkb:YP_1588(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863806|imex:IM-13779-6914	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:182050""|efo:""Orphanet:477742""|efo:""Orphanet:90635""|ensembl:ENSG00000100345.23(gene)|ensembl:ENST00000216181.11(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000212""(meiotic spindle organization)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0001931""(uropod)|go:""GO:0003723""(RNA binding)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005826""(actomyosin contractile ring)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016604""(nuclear body)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030220""(platelet formation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032418""(lysosome localization)|go:""GO:0032506""(cytokinetic process)|go:""GO:0032796""(uropod organization)|go:""GO:0032982""(myosin filament)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042641""(actomyosin)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043531""(ADP binding)|go:""GO:0043534""(blood vessel endothelial cell migration)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051015""(actin filament binding)|go:""GO:0051295""(establishment of meiotic spindle localization)|go:""GO:0060471""(cortical granule exocytosis)|go:""GO:0060473""(cortical granule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097513""(myosin II filament)|go:""GO:1903919""(negative regulation of actin filament severing)|go:""GO:1903923""(positive regulation of protein processing in phagocytic vesicle)|go:""GO:1905684""(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|reactome:R-HSA-9725370|refseq:NP_002464.1|refseq:XP_011528499.1|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|panther:PTHR45615(orthology-group)"	"interpro:IPR000527(Flagellar L-ring protein)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009427""(bacterial-type flagellum basal body, distal rod, L ring)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:WP_002211116.1|refseq:YP_002346800.1|panther:PTHR34933(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	rogid:K+hG2Y1XkdBPEZly69izKbuTRvo632	intact-crc:4F7C5ADD2CFA06D9|rigid:DAYMVi3mNhnRDliZuc3rFAtCuRI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75592	uniprotkb:Q8ZEL2	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596.2	intact:EBI-2862801|uniprotkb:Q0WF10	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	psi-mi:y2152_yerpe(display_long)|uniprotkb:YPO2152(locus name)|uniprotkb:y2169(locus name)|uniprotkb:YP_1953(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863827|imex:IM-13779-6911	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055872.4|dip:DIP-28142N|ensembl:ENSG00000005810.20(gene)|ensembl:ENST00000544440.7(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030424""(axon)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902667""(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|panther:PTHR45943(orthology-group)"	interpro:IPR006698(Protein of unknown function DUF444)|refseq:WP_002216501.1|refseq:YP_002347128.1|panther:PTHR30510(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	rogid:ltlXLZc6jWpriCSKFSImopncuEY632	intact-crc:C12C745B3027D471|rigid:yxxMVHTN+1nWYzCeLsqpeA7tq5E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z406	uniprotkb:Q8D131	intact:EBI-355595|uniprotkb:Q5CZ75|uniprotkb:Q6XYE4|uniprotkb:Q76B62|uniprotkb:Q8WV23|uniprotkb:Q96I22|uniprotkb:Q9BT27|uniprotkb:Q9BW35|uniprotkb:Q9H882|uniprotkb:B0I1S2|uniprotkb:C3TTN4|ensembl:ENSP00000366169.3|ensembl:ENSP00000472819.1	intact:EBI-2858378|uniprotkb:Q74VY8	psi-mi:myh14_human(display_long)|uniprotkb:MYH14(gene name)|psi-mi:MYH14(display_short)|uniprotkb:KIAA2034(gene name synonym)|uniprotkb:FP17425(orf name)|uniprotkb:Myosin heavy chain 14(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIc(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIc(gene name synonym)	psi-mi:q8d131_yerpe(display_long)|uniprotkb:mviM1(gene name)|psi-mi:mviM1(display_short)|uniprotkb:YP_1131(locus name)|uniprotkb:y1152(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863813|imex:IM-13779-6910	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:397744""|efo:""Orphanet:90635""|ensembl:ENSG00000105357.20(gene)|ensembl:ENST00000376970.6(transcript)|ensembl:ENST00000596571.5(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0001725""(stress fiber)|go:""GO:0003009""(skeletal muscle contraction)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005903""(brush border)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0019228""(neuronal action potential)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030426""(growth cone)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032982""(myosin filament)|go:""GO:0042641""(actomyosin)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071625""(vocalization behavior)|go:""GO:0097513""(myosin II filament)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q7Z406|rcsb pdb:5I4E|rcsb pdb:5JLH|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_001070654.1|refseq:NP_001139281.1|refseq:NP_079005.3|refseq:XP_006723449.1|refseq:XP_011525625.1|dip:DIP-33170N|panther:PTHR45615(orthology-group)"	"interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR050463|go:""GO:0000166""(nucleotide binding)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR055170|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6aY3HPa5DIY5UadiOTTh/uSPi/M9606	rogid:A5TCBtioM6Hbyj2QQ+aVDQPo8D8632	intact-crc:0D0C8F645599F1C0|rigid:vRDU87riERq6oNN9BMqijxe202Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GXB1	uniprotkb:O75592	intact:EBI-2863837|uniprotkb:A0A3N4BGW8|uniprotkb:Q0WGI9|uniprotkb:Q7CJ27|uniprotkb:A0A384KPD6	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596.2	psi-mi:a0a2u2gxb1_yerpe(display_long)|uniprotkb:YPO1588(locus name)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863834|imex:IM-13779-6912	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR007138(Antibiotic biosynthesis monooxygenase)|interpro:IPR011008(Dimeric alpha-beta barrel)|refseq:WP_002213107.1|interpro:IPR050744|refseq:YP_002346599.1	"refseq:NP_055872.4|dip:DIP-28142N|ensembl:ENSG00000005810.20(gene)|ensembl:ENST00000544440.7(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030424""(axon)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902667""(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|panther:PTHR45943(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:0BcN+IzdjufuFSI8x6A5YBfZKIc632	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:92A3DA4B11AF63A7|rigid:J4THgNThsQrFdm6KVptz6h6l+Xw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHF1	uniprotkb:O75592	intact:EBI-2849437|uniprotkb:Q0WI93	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596.2	psi-mi:glsa1_yerpe(display_long)|uniprotkb:glsA1(gene name)|psi-mi:glsA1(display_short)|uniprotkb:YPO0949(locus name)|uniprotkb:y3336(locus name)|uniprotkb:YP_3492(locus name)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863856|imex:IM-13779-6918	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|refseq:WP_002209989.1|go:""GO:0004359""(glutaminase activity)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006543""(glutamine catabolic process)|refseq:YP_002345995.1|panther:PTHR12544(orthology-group)"	"refseq:NP_055872.4|dip:DIP-28142N|ensembl:ENSG00000005810.20(gene)|ensembl:ENST00000544440.7(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030424""(axon)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902667""(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|panther:PTHR45943(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:RXiLjz5WJJYlM97YSg1neu4h+FA632	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:B605495B30C08837|rigid:5WdG1PVC4vB7RMc0Bt843Iqljhs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W593	uniprotkb:Q92614	intact:EBI-2845211|uniprotkb:Q0WG01|uniprotkb:Q7CHX2|uniprotkb:A0A384KF61	intact:EBI-949059|uniprotkb:Q5H9U3|uniprotkb:Q5W9F9|uniprotkb:Q5W9G1|uniprotkb:Q8IXP8|intact:EBI-25627010|uniprotkb:Q5QD01|ensembl:ENSP00000437073.1	psi-mi:a0a0h2w593_yerpe(display_long)|uniprotkb:flhB(gene name)|psi-mi:flhB(display_short)|uniprotkb:YPO1790(locus name)	psi-mi:my18a_human(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym)|uniprotkb:TIAF1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863877|imex:IM-13779-6917	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006136(Flagellar biosynthetic protein FlhB)|interpro:IPR006135(Type III secretion exporter)|interpro:IPR029025|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|go:""GO:0044780""(bacterial-type flagellum assembly)|refseq:WP_002211099.1|refseq:YP_002346787.1|panther:PTHR30531(orthology-group)"	"dip:DIP-46631N|refseq:NP_510880.2|refseq:NP_976063.1|refseq:NP_001333696.1|refseq:NP_001333697.1|ensembl:ENSG00000196535.20(gene)|ensembl:ENST00000527372.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0006259""(DNA metabolic process)|go:""GO:0007030""(Golgi organization)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016477""(cell migration)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032982""(myosin filament)|go:""GO:0042641""(actomyosin)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043531""(ADP binding)|go:""GO:0048194""(Golgi vesicle budding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051015""(actin filament binding)|go:""GO:0090161""(Golgi ribbon formation)|go:""GO:0090164""(asymmetric Golgi ribbon formation)|go:""GO:1903028""(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR020587|interpro:IPR027417|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|interpro:IPR041489|mint:Q92614|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|panther:PTHR45615(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:6UA0GETkNg/kZmoCiO5n6YTUjo8632	rogid:IunEYt79RO62wU6VU2gv16Xb7Lk9606	intact-crc:1B2FA29A1606E629|rigid:adqDNaKEYFXpGWjzUDd8eDi79iU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ZC68	uniprotkb:O75592	intact:EBI-2843867|uniprotkb:Q7CI72|uniprotkb:Q74UK4	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596.2	psi-mi:astd_yerpe(display_long)|uniprotkb:astD(gene name)|psi-mi:astD(display_short)|uniprotkb:Succinylglutamic semialdehyde dehydrogenase(gene name synonym)|uniprotkb:YPO1964(locus name)|uniprotkb:y2347(locus name)|uniprotkb:YP_1709(locus name)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863863|imex:IM-13779-6916	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002212030.1|interpro:IPR029510|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR017649(Succinylglutamic semialdehyde dehydrogenase)|go:""GO:0019544""(arginine catabolic process to glutamate)|go:""GO:0019545""(arginine catabolic process to succinate)|go:""GO:0043824""(succinylglutamate-semialdehyde dehydrogenase activity)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:YP_002346953.1|panther:PTHR11699(orthology-group)"	"refseq:NP_055872.4|dip:DIP-28142N|ensembl:ENSG00000005810.20(gene)|ensembl:ENST00000544440.7(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030424""(axon)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902667""(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|panther:PTHR45943(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:lAw8pbIH2i1IjXZl8H7zAJvQj0I632	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:03A5828643697EAE|rigid:vTUs90OU29WiYhTzcfvizuw5EDE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YJ91	uniprotkb:O75592	intact:EBI-2863847|uniprotkb:Q74RR0|uniprotkb:Q7CGG5|uniprotkb:Q0WJ26	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596.2	psi-mi:a0a5p8yj91_yerpe(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:dnaP(gene name synonym)|uniprotkb:parB(gene name synonym)|uniprotkb:YPO0644(locus name)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863844|imex:IM-13779-6915	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR019475|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR013173(DNA primase DnaG, DnaB-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|interpro:IPR034151|refseq:WP_002210358.1|interpro:IPR050219|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0003677""(DNA binding)|go:""GO:0003896""(obsolete DNA primase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006269""(DNA replication, synthesis of primer)|go:""GO:0008270""(zinc ion binding)|go:""GO:1990077""(primosome complex)|interpro:IPR036977|interpro:IPR037068|refseq:YP_002345712.1|interpro:IPR030846|panther:PTHR30313(orthology-group)"	"refseq:NP_055872.4|dip:DIP-28142N|ensembl:ENSG00000005810.20(gene)|ensembl:ENST00000544440.7(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030424""(axon)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902667""(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|panther:PTHR45943(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:nYz2fw8N5Xd1ZjsLUZvB+xVC36Q632	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:0CD7CED2279D8532|rigid:/HXB7Bn6fJ2P+VEqfZS8m7vjHqc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W225	uniprotkb:Q92614	intact:EBI-2844774	intact:EBI-949059|uniprotkb:Q5H9U3|uniprotkb:Q5W9F9|uniprotkb:Q5W9G1|uniprotkb:Q8IXP8|intact:EBI-25627010|uniprotkb:Q5QD01|ensembl:ENSP00000437073.1	psi-mi:a0a0h2w225_yerpe(display_long)|uniprotkb:sbcC2(gene name)|psi-mi:sbcC2(display_short)|uniprotkb:sbcC(gene name synonym)|uniprotkb:YP_0725(locus name)|uniprotkb:y0976(locus name)	psi-mi:my18a_human(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym)|uniprotkb:TIAF1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863870|imex:IM-13779-6919	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR027417|interpro:IPR038729|uniprotkb:A0A6B3T1W4(uniprot-removed-ac)|go:""GO:0004527""(exonuclease activity)|go:""GO:0006302""(double-strand break repair)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002223265.1"	"dip:DIP-46631N|refseq:NP_510880.2|refseq:NP_976063.1|refseq:NP_001333696.1|refseq:NP_001333697.1|ensembl:ENSG00000196535.20(gene)|ensembl:ENST00000527372.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0006259""(DNA metabolic process)|go:""GO:0007030""(Golgi organization)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016477""(cell migration)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032982""(myosin filament)|go:""GO:0042641""(actomyosin)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043531""(ADP binding)|go:""GO:0048194""(Golgi vesicle budding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051015""(actin filament binding)|go:""GO:0090161""(Golgi ribbon formation)|go:""GO:0090164""(asymmetric Golgi ribbon formation)|go:""GO:1903028""(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR020587|interpro:IPR027417|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|interpro:IPR041489|mint:Q92614|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|panther:PTHR45615(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:kLIIS2zCAycudIvZsl7pSdsTqz0632	rogid:IunEYt79RO62wU6VU2gv16Xb7Lk9606	intact-crc:58F39E0AD8486740|rigid:2t4QANKtLViBF0hManrU+Cd9u+I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20591	uniprotkb:A0A5P8YLE8	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599.3|ensembl:ENSP00000381601.2|ensembl:ENSP00000392151.2|ensembl:ENSP00000402215.2|ensembl:ENSP00000408498.2|ensembl:ENSP00000410523.2|ensembl:ENSP00000505029.1|ensembl:ENSP00000505047.1|ensembl:ENSP00000505051.1|ensembl:ENSP00000505189.1|ensembl:ENSP00000505457.1|ensembl:ENSP00000505489.1|ensembl:ENSP00000505630.1|ensembl:ENSP00000505657.1|ensembl:ENSP00000505669.1|ensembl:ENSP00000505781.1|ensembl:ENSP00000505874.1|ensembl:ENSP00000506047.1|ensembl:ENSP00000506062.1|ensembl:ENSP00000506183.1|ensembl:ENSP00000506199.1|ensembl:ENSP00000506220.1|ensembl:ENSP00000506270.1|ensembl:ENSP00000506348.1|ensembl:ENSP00000506372.1|ensembl:ENSP00000506395.1|ensembl:ENSP00000506481.1|ensembl:ENSP00000506512.1|ensembl:ENSP00000506690.1|ensembl:ENSP00000506712.1	intact:EBI-2841627|uniprotkb:Q74Y48|uniprotkb:A0A384L7I3|uniprotkb:A0A0H2W0Y8|uniprotkb:Q7CFX4	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:a0a5p8yle8_yerpe(display_long)|uniprotkb:malQ(gene name)|psi-mi:malQ(display_short)|uniprotkb:Amylomaltase(gene name synonym)|uniprotkb:Disproportionating enzyme(gene name synonym)|uniprotkb:YPO0126(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863884|imex:IM-13779-6924	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|ensembl:ENSG00000157601.15(gene)|ensembl:ENST00000398598.8(transcript)|ensembl:ENST00000398600.6(transcript)|ensembl:ENST00000413778.6(transcript)|ensembl:ENST00000417963.6(transcript)|ensembl:ENST00000419044.6(transcript)|ensembl:ENST00000455164.6(transcript)|ensembl:ENST00000679445.1(transcript)|ensembl:ENST00000679464.1(transcript)|ensembl:ENST00000679543.1(transcript)|ensembl:ENST00000679626.1(transcript)|ensembl:ENST00000679705.1(transcript)|ensembl:ENST00000679911.1(transcript)|ensembl:ENST00000680176.1(transcript)|ensembl:ENST00000680182.1(transcript)|ensembl:ENST00000680347.1(transcript)|ensembl:ENST00000680364.1(transcript)|ensembl:ENST00000680536.1(transcript)|ensembl:ENST00000680629.1(transcript)|ensembl:ENST00000680760.1(transcript)|ensembl:ENST00000680776.1(transcript)|ensembl:ENST00000681039.1(transcript)|ensembl:ENST00000681191.1(transcript)|ensembl:ENST00000681266.1(transcript)|ensembl:ENST00000681415.1(transcript)|ensembl:ENST00000681607.1(transcript)|ensembl:ENST00000681671.1(transcript)|ensembl:ENST00000681849.1(transcript)|ensembl:ENST00000681857.1(transcript)|ensembl:ENST00000681867.1(transcript)|ensembl:ENST00000681896.1(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006915""(apoptotic process)|go:""GO:0006952""(defense response)|go:""GO:0007165""(signal transduction)|go:""GO:0008017""(microtubule binding)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034340""(response to type I interferon)|go:""GO:0042802""(identical protein binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051607""(defense response to virus)|go:""GO:0070106""(interleukin-27-mediated signaling pathway)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR045063|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733|refseq:XP_011527870.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|panther:PTHR11566(orthology-group)"	"interpro:IPR003385(Glycoside hydrolase, family 77)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR048458|go:""GO:0004134""(4-alpha-glucanotransferase activity)|go:""GO:0005975""(carbohydrate metabolic process)|refseq:YP_002345212.1|refseq:WP_002208925.1|panther:PTHR32438(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	rogid:JdI4fLE1gbtuqHycNtXRKKfEZ7Y632	intact-crc:0D25D9D94462DA71|rigid:TIIJxjp861lFzuW9CTRAR8LnN6I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WB53	uniprotkb:Q14764	intact:EBI-2843582|uniprotkb:Q74PF7|uniprotkb:A0A0H2W9R7|uniprotkb:Q7CL30|uniprotkb:A0A5P8YK76|uniprotkb:A0A384KY07	intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977.5|ensembl:ENSP00000378760.1	psi-mi:q0wb53_yerpe(display_long)|uniprotkb:YPO3600(locus name)	psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863891|imex:IM-13779-6920	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|go:""GO:0043565""(sequence-specific DNA binding)|refseq:WP_002212108.1|refseq:YP_002348485.1"	"refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364.19(gene)|ensembl:ENST00000357402.10(transcript)|ensembl:ENST00000395353.5(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0008283""(cell population proliferation)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031953""(negative regulation of protein autophosphorylation)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051028""(mRNA transport)|go:""GO:0061099""(negative regulation of protein tyrosine kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072376""(protein activation cascade)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695|refseq:NP_001280133.1|refseq:NP_001280134.1|panther:PTHR14165(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+7ZeP5CFFak39cmFq2dxDtHUqkk632	rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606	intact-crc:ED9A2BC2153FBD92|rigid:USdlgasd4nDSt856bgiL57wB7T0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q9F287	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2854744|uniprotkb:Q7CGE2|uniprotkb:A0A384KA49|uniprotkb:A0A1U8QHS7|uniprotkb:A0A454XLL2	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:q9f287_yerpe(display_long)|uniprotkb:yapF(gene name)|psi-mi:yapF(display_short)|uniprotkb:YPO0606(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863912|imex:IM-13779-6922	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	interpro:IPR005546(Autotransporter beta-domain)|refseq:WP_002210389.1|interpro:IPR036709|refseq:YP_002345675.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:uIQ9881A2N1D063pjSQtEbbJqNs632	intact-crc:1AECB53C871803E7|rigid:G8A5t5F8VFPwDuuwvTiVcaA8zCM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q8ZDJ2	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2844031|uniprotkb:Q0WDV6	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:a2mgh_yerpe(display_long)|uniprotkb:YPO2573(locus name)|uniprotkb:y1143(locus name)|uniprotkb:YP_1141(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863905|imex:IM-13779-6921	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"interpro:IPR021868|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|go:""GO:0004866""(endopeptidase inhibitor activity)|interpro:IPR041203|interpro:IPR041246|interpro:IPR041462|refseq:YP_002347532.1|interpro:IPR051802|panther:PTHR40094(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:9FN1refl1me6jgo6ehCPO8MzV8Y632	intact-crc:8EAE5ABDF7255B90|rigid:mYOJlPP0JpkHMAj9retPlZYSN0U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q8ZD12	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2847057|uniprotkb:Q0WDB0	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:y2781_yerpe(display_long)|uniprotkb:YPO2781(locus name)|uniprotkb:y1614(locus name)|uniprotkb:YP_2383(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863898|imex:IM-13779-6923	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR024195|refseq:WP_002209742.1|go:""GO:0005737""(cytoplasm)|go:""GO:0016818""(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347728.1|panther:PTHR43758(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:+djMSbEwT6HdcEtL19C6UCvdH70632	intact-crc:59E55ABDF735A943|rigid:wbbKJ9GzpOVnSQRdy4QIzdS284s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H2H7	uniprotkb:P01871	intact:EBI-2853632|uniprotkb:Q74PQ7|uniprotkb:A0A0H2W8Q9|uniprotkb:A0A380PH97|uniprotkb:Q7CL87|uniprotkb:A0A384KJ22	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	psi-mi:a0a2u2h2h7_yerpe(display_long)|uniprotkb:yrbK(gene name)|psi-mi:yrbK(display_short)|uniprotkb:lptC(gene name synonym)|uniprotkb:YPO3579(locus name)	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863926|imex:IM-13779-6928	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR052363|interpro:IPR010664(Protein of unknown function DUF1239)|interpro:IPR026265|refseq:WP_002218352.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015221""(lipopolysaccharide transmembrane transporter activity)|go:""GO:0043165""(Gram-negative-bacterium-type cell outer membrane assembly)|refseq:YP_002348466.1"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aDJ16CEXIG/yEvICO07srgHr4Ik632	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	intact-crc:43740B8FDDF00AC2|rigid:j6Pvsl8RVVv1xetDHxZrRFvxJKU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:A0A3N4BNK4	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2855448|uniprotkb:A0A380PK27|uniprotkb:Q0WDQ1|uniprotkb:Q7CJU1	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:a0a3n4bnk4_yerpe(display_long)|uniprotkb:ybfM(gene name)|psi-mi:ybfM(display_short)|uniprotkb:YPO2631(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863947|imex:IM-13779-6929	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"interpro:IPR005318(Outer membrane porin, bacterial)|refseq:WP_002210355.1|go:""GO:0016020""(membrane)|interpro:IPR023614|refseq:YP_002347587.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:kQOm62Hk7MNtNLAcnBC4bzThrBs632	intact-crc:D224A744EFEC07B0|rigid:2CZLmAuteyuFOX5TLk0g3XwvlXI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q8CL50	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2857335	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:q8cl50_yerpe(display_long)|uniprotkb:y2187(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863919|imex:IM-13779-6925	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	interpro:IPR045604	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:jt6BQ8hZFhQrWjllEvfW2r4RX60632	intact-crc:8F913354F78D26AC|rigid:+ZSAOqdBPkikiwaQz3yftrbpFxw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:A0A0H2W174	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2857409|uniprotkb:Q74WU9|uniprotkb:A0A3N4BLR1|uniprotkb:Q7CK49|uniprotkb:Q0WC84	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:a0a0h2w174_yerpe(display_long)|uniprotkb:malZ(gene name)|psi-mi:malZ(display_short)|uniprotkb:YPO3200(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863933|imex:IM-13779-6926	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004185(Glycoside hydrolase, family 13, N-terminal Ig-like region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017069(Maltodextrin glucosidase)|refseq:WP_002208678.1|go:""GO:0004558""(alpha-1,4-glucosidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:YP_002348104.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:xXWAIuIiT4Lo4aYGy1vcRouNeV4632	intact-crc:25D8299E8C6DA620|rigid:9k2zJ1Gp6IUcoDTMkkCczpIDNq0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GVZ6	uniprotkb:P01871	intact:EBI-2842971|uniprotkb:Q74W16|uniprotkb:A0A0H2W2X1|uniprotkb:Q7CJU6|uniprotkb:A0A3N4AZS9|uniprotkb:A0A384L7G7	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	psi-mi:a0a2u2gvz6_yerpe(display_long)|uniprotkb:ubiF(gene name)|psi-mi:ubiF(display_short)|uniprotkb:YPO2621(locus name)	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863940|imex:IM-13779-6927	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR010971(Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6)|go:""GO:0004497""(monooxygenase activity)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0016705""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:""GO:0071949""(FAD binding)|refseq:WP_002210347.1|interpro:IPR036188|refseq:YP_002347577.1|interpro:IPR051205"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zKOVHd4RmzcakJDi4rlK0Xy9yNc632	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	intact-crc:840A774F0A48F5CF|rigid:fqKCqekduI29YdGvRUgG+LW3DPA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W5A0	uniprotkb:P01871	intact:EBI-2860643|uniprotkb:Q74TI3|uniprotkb:Q7CIS3|uniprotkb:A0A380SAX2|uniprotkb:Q0WED4	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	psi-mi:a0a0h2w5a0_yerpe(display_long)|uniprotkb:YPO2388(locus name)	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863954|imex:IM-13779-6934	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|refseq:WP_002210942.1|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|refseq:YP_002347354.1"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qusIJwX33yQEbGFFOo0bTmjGhto632	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	intact-crc:4063EEE0BBE41938|rigid:uBiz1/vI7dELQ71rq4OuBvPymmg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q8ZA10	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2863988|uniprotkb:Q0WA06	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:huth_yerpe(display_long)|uniprotkb:hutH(gene name)|psi-mi:hutH(display_short)|uniprotkb:YPO4016(locus name)|uniprotkb:y4037(locus name)|uniprotkb:YP_3379(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863985|imex:IM-13779-6932	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"interpro:IPR005921(Histidine ammonia-lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR024083|interpro:IPR001106(Phenylalanine/histidine ammonia-lyase)|interpro:IPR022313|refseq:WP_002209575.1|go:""GO:0004397""(histidine ammonia-lyase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006548""(L-histidine catabolic process)|go:""GO:0019556""(L-histidine catabolic process to glutamate and formamide)|go:""GO:0019557""(L-histidine catabolic process to glutamate and formate)|refseq:YP_002348882.1|panther:PTHR10362(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:jfXJCI9lqUpuGfp4zklLnxz/qCs632	intact-crc:D84DEFBDF78C569E|rigid:nnGCwRAfGSG8/YmgAAMk944Xaik	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PJW4	uniprotkb:P01871	intact:EBI-2847196|uniprotkb:Q0WI94|uniprotkb:Q7CGR6	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	psi-mi:a0a380pjw4_yerpe(display_long)|uniprotkb:YPO0947(locus name)	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863961|imex:IM-13779-6930	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020974|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|interpro:IPR028994|refseq:WP_002224905.1|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016740""(transferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR038383|refseq:YP_002345994.1|interpro:IPR049824"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3Aj0qy9DiLKc8Bx9KbIJWyE+XAM632	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	intact-crc:ACE7DAB1C1139071|rigid:TxoAIHvqR0HJfIjtjWczrvdU84g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:A0A5P8YJS7	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2863975|uniprotkb:Q0WJR4|uniprotkb:Q7CG38|uniprotkb:A0A384LPL9	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:a0a5p8yjs7_yerpe(display_long)|uniprotkb:YPO0397(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863978|imex:IM-13779-6931	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	interpro:IPR024534|interpro:IPR024537|interpro:IPR014544(Uncharacterized conserved protein UCP028408)|refseq:WP_002209174.1|refseq:YP_002345474.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:4d4c4vkH5Vwn3hSo6Gl3/NRs8lU632	intact-crc:2AD1CC0445F1E17A|rigid:JrKCGLAjZCiCd8RX9vNXWaMPvWM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WI51	uniprotkb:P01871	intact:EBI-2840107|uniprotkb:Q74QL6|uniprotkb:A0A0H2W7W5|uniprotkb:Q7CGN8|uniprotkb:A0A3N4B896	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	psi-mi:q0wi51_yerpe(display_long)|uniprotkb:iucC(gene name)|psi-mi:iucC(display_short)|uniprotkb:YPO0992(locus name)	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863968|imex:IM-13779-6933	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002346037.1|interpro:IPR007310(IucA/IucC)|interpro:IPR022770|go:""GO:0019290""(siderophore biosynthetic process)|refseq:WP_002211648.1|interpro:IPR037455"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:S0y74aGL7KNY1nTtgrJEgy/Qaj4632	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	intact-crc:3091A26B7FD1D8FE|rigid:dpTkQoTYFwVFyjRWDZOo4m9ubOs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJF3	uniprotkb:P01871	intact:EBI-2850095|uniprotkb:Q0WKE6	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	psi-mi:gph_yerpe(display_long)|uniprotkb:gph(gene name)|psi-mi:gph(display_short)|uniprotkb:YPO0156(locus name)|uniprotkb:y3939(locus name)|uniprotkb:YP_0158(locus name)	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2863997|imex:IM-13779-6935	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|interpro:IPR037512|refseq:WP_002208892.1|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006281""(DNA repair)|go:""GO:0008967""(phosphoglycolate phosphatase activity)|go:""GO:0046295""(glycolate biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR036412|interpro:IPR041492|refseq:YP_002345242.1|interpro:IPR050155|panther:PTHR43434(orthology-group)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:n2m9iPEoLBOpfauijcWx/W/lq+M632	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	intact-crc:65C6F4BDF77A33C2|rigid:Dqs5ijYqCHI6/stvFkDlyceqljo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:Q9X6B0	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2844324|intact:EBI-2856296|uniprotkb:Q0WBX3	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:katg_yerpe(display_long)|uniprotkb:katG(gene name)|psi-mi:katG(display_short)|uniprotkb:katY(gene name synonym)|uniprotkb:Antigen 5(gene name synonym)|uniprotkb:Peroxidase/catalase(gene name synonym)|uniprotkb:YPO3319(locus name)|uniprotkb:y0870(locus name)|uniprotkb:YP_0367(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864004|imex:IM-13779-6938	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"interpro:IPR000763(Catalase-peroxidase haem)|interpro:IPR010255(Haem peroxidase)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR019794|interpro:IPR019793|go:""GO:0004096""(catalase activity)|go:""GO:0005829""(cytosol)|go:""GO:0020037""(heme binding)|go:""GO:0042597""(periplasmic space)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|refseq:WP_002209433.1|refseq:YP_002348215.1|panther:PTHR30555(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:RBebELhpxkVGfQv9Ix9rW4jzmpE632	intact-crc:E5CA8282869E50D0|rigid:T8wmnnPmVCx/X4puujywANPCS5I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99102	uniprotkb:A0A2S9PJN0	intact:EBI-2864014|uniprotkb:Q9H485|uniprotkb:Q9NY76|uniprotkb:Q9NY77|uniprotkb:Q9NY09|uniprotkb:Q9NY80|uniprotkb:Q9H4D6|uniprotkb:Q9H484|uniprotkb:Q9GZM2|uniprotkb:Q9NY78|uniprotkb:Q9H487|uniprotkb:Q9H481|uniprotkb:Q9NY79|uniprotkb:Q9H482|uniprotkb:O95938|uniprotkb:Q9NPJ0|uniprotkb:Q9H4D8|uniprotkb:Q9GZV6|uniprotkb:Q9NY75|uniprotkb:Q9H486|uniprotkb:Q9H483|uniprotkb:Q9NY81|ensembl:ENSP00000417498.3	intact:EBI-2848458|uniprotkb:Q74XE8|uniprotkb:A0A0H2W321|uniprotkb:Q7CKP0|uniprotkb:A0A384KEH5	psi-mi:muc4_human(display_long)|uniprotkb:MUC4(gene name)|psi-mi:MUC4(display_short)|uniprotkb:Ascites sialoglycoprotein(gene name synonym)|uniprotkb:Pancreatic adenocarcinoma mucin(gene name synonym)|uniprotkb:Testis mucin(gene name synonym)|uniprotkb:Tracheobronchial mucin(gene name synonym)	psi-mi:a0a2s9pjn0_yerpe(display_long)|uniprotkb:YPO0327(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864011|imex:IM-13779-6936	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004523.3|refseq:NP_060876.5|refseq:NP_612154.2|ensembl:ENSG00000145113.22(gene)|ensembl:ENST00000463781.8(transcript)|go:""GO:0005176""(ErbB-2 class receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0016020""(membrane)|go:""GO:0030197""(extracellular matrix constituent, lubricant activity)|go:""GO:0030277""(maintenance of gastrointestinal epithelium)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031982""(vesicle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR005533(AMOP)|interpro:IPR051495|reactome:R-HSA-5083625|reactome:R-HSA-5083632|reactome:R-HSA-5083636|reactome:R-HSA-5621480|reactome:R-HSA-913709|reactome:R-HSA-977068|panther:PTHR13802(orthology-group)"	"interpro:IPR001670(Iron-containing alcohol dehydrogenase)|interpro:IPR013460(Lactaldehyde reductase)|interpro:IPR018211|refseq:WP_002209102.1|go:""GO:0004022""(""alcohol dehydrogenase (NAD+) activity"")|go:""GO:0046872""(metal ion binding)|go:""GO:0050093""(""methanol dehydrogenase (NAD+) activity"")|interpro:IPR039697|refseq:YP_002345407.1|panther:PTHR11496(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t42yGCVFriSZ2QFUWOpEpMdYDKM9606	rogid:a5XWJKRLg8L6JLHmBu7QTvqa0u0632	intact-crc:145B4340AFC7DA04|rigid:cjVRABev+ZKdno49S2bPbencVuE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2Z2	uniprotkb:P17778	intact:EBI-2864055|uniprotkb:Q5SWL2|uniprotkb:Q8NDN7|uniprotkb:Q5SWL4|uniprotkb:B3KQB5|uniprotkb:Q8WZ57|uniprotkb:Q5SWL3|uniprotkb:Q9BS06|uniprotkb:Q96FE6|ensembl:ENSP00000359323.4	intact:EBI-2842665|uniprotkb:O68701	psi-mi:mto1_human(display_long)|uniprotkb:MTO1(gene name)|psi-mi:MTO1(display_short)|uniprotkb:CGI-02(orf name)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864052|imex:IM-13779-6939	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314637""|ensembl:ENSG00000135297.17(gene)|ensembl:ENST00000370300.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070899""(mitochondrial tRNA wobble uridine modification)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|interpro:IPR026904|interpro:IPR036188|interpro:IPR040131|interpro:IPR044920|interpro:IPR047001|interpro:IPR049312|mint:Q9Y2Z2|reactome:R-HSA-6787450|refseq:NP_001116698.1|refseq:NP_036255.2|refseq:NP_598400.1|panther:PTHR11806(orthology-group)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SEHqgclQ+heHG/iQNequUOKLKvY9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:AD9C0803F54B1C6D|rigid:pb0kPrLJkWDtfdHHAI2qzbAfq3g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43312	uniprotkb:Q8D1P4	intact:EBI-473954|uniprotkb:Q8TCA2|uniprotkb:Q96RX2|uniprotkb:J3KNK6|ensembl:ENSP00000429064.1	intact:EBI-2845144	psi-mi:mtss1_human(display_long)|uniprotkb:Missing in metastasis protein(gene name synonym)|uniprotkb:Metastasis suppressor YGL-1(gene name synonym)|uniprotkb:MTSS1(gene name)|psi-mi:MTSS1(display_short)|uniprotkb:KIAA0429(gene name synonym)|uniprotkb:MIM(gene name synonym)|uniprotkb:Metastasis suppressor protein 1(gene name synonym)	psi-mi:q8d1p4_yerpe(display_long)|uniprotkb:y0195(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864045|imex:IM-13779-6937	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269903.1|refseq:NP_055566.3|refseq:NP_001269900.1|ensembl:ENSG00000170873.19(gene)|ensembl:ENST00000518547.6(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0003779""(actin binding)|go:""GO:0003785""(actin monomer binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0007009""(plasma membrane organization)|go:""GO:0007155""(cell adhesion)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030035""(microspike assembly)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0032233""(positive regulation of actin filament bundle assembly)|go:""GO:0034334""(adherens junction maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0061333""(renal tubule morphogenesis)|go:""GO:0071498""(cellular response to fluid shear stress)|go:""GO:0072102""(glomerulus morphogenesis)|go:""GO:0072160""(nephron tubule epithelial cell differentiation)|go:""GO:2001013""(epithelial cell proliferation involved in renal tubule morphogenesis)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR013606(""IRSp53/MIM homology domain (IMD)"")|interpro:IPR027267|interpro:IPR030127|mint:O43312|rcsb pdb:2D1K|dip:DIP-17022N|panther:PTHR15708(orthology-group)"	interpro:IPR032712|interpro:IPR025263|interpro:IPR011836(Conserved hypothetical protein CHP02099)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iFdj9byryurwGO1kTYLFzu6cEgI9606	rogid:k1ALZgWrTdqeyJ1mZBZgusKWD8Y632	intact-crc:CFF0D9C6E23B5503|rigid:NjLCHOYKv2ddMmbliI+ww4oRZqc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BNK4	uniprotkb:O95248	intact:EBI-2855448|uniprotkb:A0A380PK27|uniprotkb:Q0WDQ1|uniprotkb:Q7CJU1	intact:EBI-2322878|uniprotkb:A6PVG9|uniprotkb:O60228|uniprotkb:Q5JXD8|uniprotkb:Q5PPM2|uniprotkb:Q96GR9|uniprotkb:Q9UGB8|uniprotkb:A0A024R4Z9|uniprotkb:G5E933|ensembl:ENSP00000510414.1	psi-mi:a0a3n4bnk4_yerpe(display_long)|uniprotkb:ybfM(gene name)|psi-mi:ybfM(display_short)|uniprotkb:YPO2631(locus name)	psi-mi:mtmr5_human(display_long)|uniprotkb:SBF1(gene name)|psi-mi:SBF1(display_short)|uniprotkb:MTMR5(gene name synonym)|uniprotkb:SET-binding factor 1(gene name synonym)|uniprotkb:Inactive phosphatidylinositol 3-phosphatase 5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864071|imex:IM-13779-6944	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005318(Outer membrane porin, bacterial)|refseq:WP_002210355.1|go:""GO:0016020""(membrane)|interpro:IPR023614|refseq:YP_002347587.1"	"ensembl:ENSG00000100241.22(gene)|ensembl:ENST00000689129.1(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0007286""(spermatid development)|go:""GO:0008138""(protein tyrosine/serine/threonine phosphatase activity)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0043005""(neuron projection)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR001194(DENN)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004182(GRAM)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022096|interpro:IPR029021|interpro:IPR030564|interpro:IPR037516|interpro:IPR043153|mint:O95248|reactome:R-HSA-1483248|reactome:R-HSA-8876198|refseq:NP_002963.2|efo:""Orphanet:363981""|panther:PTHR10807(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kQOm62Hk7MNtNLAcnBC4bzThrBs632	rogid:VTuIGKsw1QF3CSAFzIFnufmVGU09606	intact-crc:A3DCEB5B58B9A32C|rigid:fONiV5AGg/sfeFx4QartOnJVIJs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q13614	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-475631|ensembl:ENSP00000345752.6|uniprotkb:Q9UPS9|uniprotkb:A6NN98	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:mtmr2_human(display_long)|uniprotkb:MTMR2(gene name)|psi-mi:MTMR2(display_short)|uniprotkb:KIAA1073(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)|uniprotkb:Myotubularin-related protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864092|imex:IM-13779-6941	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"ensembl:ENSG00000087053.20(gene)|ensembl:ENST00000346299.10(transcript)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0004438""(phosphatidylinositol-3-phosphate phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031642""(negative regulation of myelination)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032288""(myelin assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048666""(neuron development)|go:""GO:0052629""(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:""GO:0060304""(regulation of phosphatidylinositol dephosphorylation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090394""(negative regulation of excitatory postsynaptic potential)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|go:""GO:2000645""(negative regulation of receptor catabolic process)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004182(GRAM)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR030564|mint:Q13614|rcsb pdb:1LW3|rcsb pdb:1M7R|rcsb pdb:1ZSQ|rcsb pdb:1ZVR|rcsb pdb:5GNH|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660516|reactome:R-HSA-1660517|refseq:NP_001230500.1|refseq:NP_057240.3|refseq:NP_958435.1|refseq:NP_958438.1|refseq:XP_005274431.1|refseq:XP_005274432.1|refseq:XP_006718997.1|refseq:XP_006718998.1|refseq:XP_006718999.1|refseq:XP_016874006.1|refseq:XP_016874007.1|efo:""Orphanet:99955""|panther:PTHR10807(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:NIG+mKVVhMYEsCU20hoVInG8EOw9606	intact-crc:6A8259427669C16C|rigid:hYkFaYQ0SmYh4negSA1y5XQ0+uY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZH40	uniprotkb:Q13614	intact:EBI-2853216|uniprotkb:Q0WHX3	intact:EBI-475631|ensembl:ENSP00000345752.6|uniprotkb:Q9UPS9|uniprotkb:A6NN98	psi-mi:metq_yerpe(display_long)|uniprotkb:metQ(gene name)|psi-mi:metQ(display_short)|uniprotkb:YPO1071(locus name)|uniprotkb:y3106(locus name)|uniprotkb:YP_2778(locus name)	psi-mi:mtmr2_human(display_long)|uniprotkb:MTMR2(gene name)|psi-mi:MTMR2(display_short)|uniprotkb:KIAA1073(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)|uniprotkb:Myotubularin-related protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864099|imex:IM-13779-6942	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004872(NLPA lipoprotein)|refseq:WP_002212159.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|refseq:YP_002346115.1|panther:PTHR30429(orthology-group)"	"ensembl:ENSG00000087053.20(gene)|ensembl:ENST00000346299.10(transcript)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0004438""(phosphatidylinositol-3-phosphate phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031642""(negative regulation of myelination)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032288""(myelin assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048666""(neuron development)|go:""GO:0052629""(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:""GO:0060304""(regulation of phosphatidylinositol dephosphorylation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090394""(negative regulation of excitatory postsynaptic potential)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|go:""GO:2000645""(negative regulation of receptor catabolic process)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004182(GRAM)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR030564|mint:Q13614|rcsb pdb:1LW3|rcsb pdb:1M7R|rcsb pdb:1ZSQ|rcsb pdb:1ZVR|rcsb pdb:5GNH|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660516|reactome:R-HSA-1660517|refseq:NP_001230500.1|refseq:NP_057240.3|refseq:NP_958435.1|refseq:NP_958438.1|refseq:XP_005274431.1|refseq:XP_005274432.1|refseq:XP_006718997.1|refseq:XP_006718998.1|refseq:XP_006718999.1|refseq:XP_016874006.1|refseq:XP_016874007.1|efo:""Orphanet:99955""|panther:PTHR10807(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Q6fJ70CWCE/DbbUHlJ9Z7HHzEig632	rogid:NIG+mKVVhMYEsCU20hoVInG8EOw9606	intact-crc:343ECCB0A99E3758|rigid:uQ1xJoq2q7oi7f3lAjxO2/tBldM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1P8	uniprotkb:Q13614	intact:EBI-2841883	intact:EBI-475631|ensembl:ENSP00000345752.6|uniprotkb:Q9UPS9|uniprotkb:A6NN98	psi-mi:q8d1p8_yerpe(display_long)|uniprotkb:tcaA1(gene name)|psi-mi:tcaA1(display_short)|uniprotkb:y0183(locus name)	psi-mi:mtmr2_human(display_long)|uniprotkb:MTMR2(gene name)|psi-mi:MTMR2(display_short)|uniprotkb:KIAA1073(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)|uniprotkb:Myotubularin-related protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864085|imex:IM-13779-6943	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR018003	"ensembl:ENSG00000087053.20(gene)|ensembl:ENST00000346299.10(transcript)|go:""GO:0002091""(negative regulation of receptor internalization)|go:""GO:0004438""(phosphatidylinositol-3-phosphate phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031642""(negative regulation of myelination)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032288""(myelin assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0043197""(dendritic spine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048666""(neuron development)|go:""GO:0052629""(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:""GO:0060304""(regulation of phosphatidylinositol dephosphorylation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090394""(negative regulation of excitatory postsynaptic potential)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|go:""GO:2000645""(negative regulation of receptor catabolic process)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004182(GRAM)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR030564|mint:Q13614|rcsb pdb:1LW3|rcsb pdb:1M7R|rcsb pdb:1ZSQ|rcsb pdb:1ZVR|rcsb pdb:5GNH|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660516|reactome:R-HSA-1660517|refseq:NP_001230500.1|refseq:NP_057240.3|refseq:NP_958435.1|refseq:NP_958438.1|refseq:XP_005274431.1|refseq:XP_005274432.1|refseq:XP_006718997.1|refseq:XP_006718998.1|refseq:XP_006718999.1|refseq:XP_016874006.1|refseq:XP_016874007.1|efo:""Orphanet:99955""|panther:PTHR10807(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LfA2Lz71pTe9HDOA0UOS0/RgEsY632	rogid:NIG+mKVVhMYEsCU20hoVInG8EOw9606	intact-crc:A86E960EAB6F90FD|rigid:o9cFTKnaP65d4Kn6wnFnm4ggruE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YGL8	uniprotkb:Q13615	intact:EBI-2845909|uniprotkb:Q74VS1|uniprotkb:Q0WH41|uniprotkb:Q7CHI6|uniprotkb:A0A384L3E0	intact:EBI-371938|uniprotkb:Q9NYN5|uniprotkb:Q9NYN6|uniprotkb:Q9UDX6|uniprotkb:Q9UEG3|uniprotkb:A5PL26|uniprotkb:A7MD32|ensembl:ENSP00000384651.3|intact:EBI-28971617	psi-mi:a0a5p8ygl8_yerpe(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:YPO1374(locus name)	psi-mi:mtmr3_human(display_long)|uniprotkb:MTMR3(gene name)|psi-mi:MTMR3(display_short)|uniprotkb:FYVE domain-containing dual specificity protein phosphatase 1(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 10(gene name synonym)|uniprotkb:KIAA0371(gene name synonym)|uniprotkb:ZFYVE10(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)|uniprotkb:Myotubularin-related protein 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864078|imex:IM-13779-6940	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0019430""(removal of superoxide radicals)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_002211341.1|interpro:IPR036188|refseq:YP_002346397.1|interpro:IPR050097|panther:PTHR48105(orthology-group)"	"refseq:NP_066576.1|refseq:NP_694690.1|refseq:NP_694691.1|ensembl:ENSG00000100330.16(gene)|ensembl:ENST00000401950.7(transcript)|go:""GO:0004438""(phosphatidylinositol-3-phosphate phosphatase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0061952""(midbody abscission)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0008138""(protein tyrosine/serine/threonine phosphatase activity)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|go:""GO:0046872""(metal ion binding)|go:""GO:0052629""(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060304""(regulation of phosphatidylinositol dephosphorylation)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1904562""(phosphatidylinositol 5-phosphate metabolic process)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR029021|interpro:IPR030564|interpro:IPR035888|interpro:IPR046352|mint:Q13615|reactome:R-HSA-1632852|reactome:R-HSA-1660499|refseq:XP_016884521.1|panther:PTHR10807(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lNjtMW37Ur6Z7pzA6LzMVzq9VCU632	rogid:6YquGTCQYgFfrhdj1Iqtzgd9tP49606	intact-crc:987DFCF30CC89149|rigid:BilLNzZHtbXRSjs8Ct378jY3mlI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q56990	uniprotkb:P47224	intact:EBI-2864126|uniprotkb:Q0WK24	intact:EBI-713992|uniprotkb:Q92992|uniprotkb:B2R4P4|ensembl:ENSP00000356231.3	psi-mi:hmus_yerpe(display_long)|uniprotkb:hmuS(gene name)|psi-mi:hmuS(display_short)|uniprotkb:YPO0282(locus name)|uniprotkb:y0542(locus name)|uniprotkb:YP_0437(locus name)	psi-mi:mss4_human(display_long)|uniprotkb:Rab-interacting factor(gene name synonym)|uniprotkb:RABIF(gene name)|psi-mi:RABIF(display_short)|uniprotkb:MSS4(gene name synonym)|uniprotkb:RASGRF3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864131|imex:IM-13779-6946	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007845(Haemin-degrading)|refseq:WP_002209061.1|interpro:IPR053733|go:""GO:0006826""(iron ion transport)|refseq:YP_002345364.1"	"refseq:NP_002862.2|ensembl:ENSG00000183155.5(gene)|ensembl:ENST00000367262.4(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0006892""(post-Golgi vesicle-mediated transport)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0008270""(zinc ion binding)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0061025""(membrane fusion)|interpro:IPR007515(Mss4)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|mint:P47224|rcsb pdb:1FWQ|rcsb pdb:2FU5|panther:PTHR13276(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:abJOxVEwPLMxqbI8GxJD5gpGb9k632	rogid:BDlOz1AZhYAV6xVZZu0ZLb58po49606	intact-crc:BA5C078053853D30|rigid:YOApvjeBN68zRNmxD6pO5kkEdt4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WJT0	uniprotkb:Q13496	intact:EBI-2848005|uniprotkb:A0A3N4BBH4|uniprotkb:Q74XB0|uniprotkb:A0A0H2W350|uniprotkb:Q7CKL8|uniprotkb:A0A384LB40	intact:EBI-2864109|ensembl:ENSP00000359423.3|ensembl:ENSP00000508718.1|ensembl:ENSP00000509266.1|uniprotkb:Q8NEL1|uniprotkb:A6NDB1|uniprotkb:B7Z491|uniprotkb:F2Z330	psi-mi:q0wjt0_yerpe(display_long)|uniprotkb:rnr(gene name)|psi-mi:rnr(display_short)|uniprotkb:vacB(gene name synonym)|uniprotkb:YPO0380(locus name)	psi-mi:mtm1_human(display_long)|uniprotkb:MTM1(gene name)|psi-mi:MTM1(display_short)|uniprotkb:CG2(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864106|imex:IM-13779-6945	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011805(Ribonuclease R, bacterial)|interpro:IPR013668(Ribonuclease R winged-helix domain)|interpro:IPR040476|refseq:WP_002209159.1|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008859""(exoribonuclease II activity)|go:""GO:0016070""(RNA metabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:YP_002345458.1|interpro:IPR050180"	"ensembl:ENSG00000171100.16(gene)|ensembl:ENST00000370396.7(transcript)|ensembl:ENST00000685944.1(transcript)|ensembl:ENST00000689694.1(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0001726""(ruffle)|go:""GO:0004438""(phosphatidylinositol-3-phosphate phosphatase activity)|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006470""(protein dephosphorylation)|go:""GO:0006661""(phosphatidylinositol biosynthetic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019215""(intermediate filament binding)|go:""GO:0030175""(filopodium)|go:""GO:0031674""(I band)|go:""GO:0031929""(TOR signaling)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0044088""(regulation of vacuole organization)|go:""GO:0045109""(intermediate filament organization)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|go:""GO:0048311""(mitochondrion distribution)|go:""GO:0048630""(skeletal muscle tissue growth)|go:""GO:0048633""(positive regulation of skeletal muscle tissue growth)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0052629""(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:""GO:1902902""(negative regulation of autophagosome assembly)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004182(GRAM)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR030564|mint:Q13496|reactome:R-HSA-1660499|reactome:R-HSA-1660516|reactome:R-HSA-1660517|refseq:NP_000243.1|refseq:XP_005274744.1|refseq:XP_011529475.1|refseq:XP_016885039.1|efo:""Orphanet:456328""|efo:""Orphanet:596""|dip:DIP-61934N|panther:PTHR10807(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:jBGTi4O5QHZXkNIanuHOpATLT7Q632	rogid:M4w0bu6vAz5ALjDZDpmAr+lILJI9606	intact-crc:2EDE0E511EA1C25E|rigid:S9S/G3/xgQObiAosFV2Z4+qoHx8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ZC63	uniprotkb:Q9GZW8	intact:EBI-2852813|uniprotkb:Q74UK9|uniprotkb:Q7CI70|uniprotkb:A0A384LPP0|uniprotkb:A0A5P8YG12|uniprotkb:A0A1U8QKJ4|uniprotkb:A0A0H2W4F3	intact:EBI-721391|uniprotkb:Q6IAG8|uniprotkb:A6NP53|ensembl:ENSP00000300184.3	psi-mi:q9zc63_yerpe(display_long)|uniprotkb:chaA(gene name)|psi-mi:chaA(display_short)|uniprotkb:YPO1958(locus name)	psi-mi:ms4a7_human(display_long)|uniprotkb:CD20/FC-epsilon-RI-beta family member 4(gene name synonym)|uniprotkb:Four-span transmembrane protein 2(gene name synonym)|uniprotkb:CD20 antigen-like 4(gene name synonym)|uniprotkb:MS4A7(gene name)|psi-mi:MS4A7(display_short)|uniprotkb:4SPAN2(gene name synonym)|uniprotkb:CD20L4(gene name synonym)|uniprotkb:CFFM4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864145|imex:IM-13779-6949	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR052946|interpro:IPR004837(Sodium/calcium exchanger membrane region)|refseq:WP_002212036.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015385""(""sodium:proton antiporter activity"")|go:""GO:0015386""(""potassium:proton antiporter activity"")|refseq:YP_002346947.1|panther:PTHR37958(orthology-group)"	"refseq:NP_067024.1|refseq:NP_996821.1|refseq:NP_996822.1|refseq:NP_996823.1|ensembl:ENSG00000166927.13(gene)|ensembl:ENST00000300184.8(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030417|panther:PTHR23320(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tOA91S4sk9W0hkkagdx2sTk+Rf4632	rogid:EM5VH9/XeGVfRztyVsCxC67VxMY9606	intact-crc:2FA53C0FEA28ED26|rigid:cbt621Nh96w8thvomvCIddT09fs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75081	uniprotkb:Q8D068	intact:EBI-1190217|uniprotkb:O60615|uniprotkb:O60616|uniprotkb:O60617|uniprotkb:O75082|uniprotkb:O75107|uniprotkb:O75108|uniprotkb:Q6P5W6|uniprotkb:Q0P5Z6|uniprotkb:D3DX78|intact:EBI-28983666|ensembl:ENSP00000268679.4	intact:EBI-2846153|uniprotkb:Q74VD0	psi-mi:mtg16_human(display_long)|uniprotkb:MTG16(gene name synonym)|uniprotkb:MTGR2(gene name synonym)|uniprotkb:ZMYND4(gene name synonym)|uniprotkb:Myeloid translocation gene on chromosome 16 protein(gene name synonym)|uniprotkb:MTG8-related protein 2(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 4(gene name synonym)|uniprotkb:CBFA2T3(gene name)|psi-mi:CBFA2T3(display_short)	psi-mi:q8d068_yerpe(display_long)|uniprotkb:uup3(gene name)|psi-mi:uup3(display_short)|uniprotkb:YP_1381(locus name)|uniprotkb:y2677(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864119|imex:IM-13779-6948	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR10379(orthology-group)|dip:DIP-48898N|ensembl:ENSG00000129993.15(gene)|ensembl:ENST00000268679.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001666""(response to hypoxia)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0030851""(granulocyte differentiation)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0045820""(negative regulation of glycolytic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:1903715""(regulation of aerobic respiration)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013292(""Myeloid transforming gene on chromosome 16 (MTG16)"")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:O75081|rcsb pdb:9DE2|refseq:NP_005178.4|refseq:NP_787127.1|efo:""Orphanet:329469"""	"interpro:IPR032781|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR050611"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YMP60LeA62hg4mNz15o70E/PqwE9606	rogid:uq/st091dJjwV1JggBt3SaIlbSQ632	intact-crc:FF94265BA4C3C10E|rigid:vMwBeZCCTBkWXgzHP3JxxebSHFY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H2W8	uniprotkb:Q9HCI7	intact:EBI-2859062|uniprotkb:Q74R22|uniprotkb:A0A5P8YCG3|uniprotkb:A0A0H2W7C6|uniprotkb:Q7CKV2|uniprotkb:A0A384L4Z3	intact:EBI-2560775|uniprotkb:Q8NDB4|uniprotkb:Q9NVS4|uniprotkb:Q0D2P1|ensembl:ENSP00000311827.2|uniprotkb:B4DYL4|uniprotkb:G5E9I1	psi-mi:a0a2u2h2w8_yerpe(display_long)|uniprotkb:YPO3785(locus name)	psi-mi:msl2_human(display_long)|uniprotkb:MSL2(gene name)|psi-mi:MSL2(display_short)|uniprotkb:KIAA1585(gene name synonym)|uniprotkb:MSL2L1(gene name synonym)|uniprotkb:RNF184(gene name synonym)|uniprotkb:Male-specific lethal 2-like 1(gene name synonym)|uniprotkb:Male-specific lethal-2 homolog 1(gene name synonym)|uniprotkb:RING finger protein 184(gene name synonym)|uniprotkb:Male-specific lethal-2 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864138|imex:IM-13779-6947	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026893|interpro:IPR029021|refseq:WP_002228183.1|go:""GO:0004721""(phosphoprotein phosphatase activity)|refseq:YP_002348662.1"	"refseq:NP_001138889.1|refseq:NP_060603.2|refseq:XP_011511251.1|ensembl:ENSG00000174579.5(gene)|ensembl:ENST00000309993.3(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006974""(DNA damage response)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0072487""(MSL complex)|go:""GO:0140585""(promoter-enhancer loop anchoring activity)|go:""GO:0141054""(histone H2B ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032043|interpro:IPR032049|interpro:IPR033467|interpro:IPR037922|mint:Q9HCI7|rcsb pdb:4B7Y|rcsb pdb:4B86|reactome:R-HSA-3214847|refseq:XP_005247628.1|refseq:XP_006713747.1|panther:PTHR16048(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/6YZnelr1WaabkYNEObn+bBuB6E632	rogid:kJp6Yylwcfca/FBNpVGo7y8pbcE9606	intact-crc:1DB5534AC47F9387|rigid:2KWkvFFMbk3HgDGKDDbWi90H7KA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75970	uniprotkb:A0A2U2GWQ4	intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|uniprotkb:B2RTS3|ensembl:ENSP00000320006.7|intact:EBI-10961605	intact:EBI-2845580|uniprotkb:Q74SR7|uniprotkb:Q0WDH9|uniprotkb:Q7CJQ8|uniprotkb:A0A380PMW3|uniprotkb:A0A384L966	psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym)	psi-mi:a0a2u2gwq4_yerpe(display_long)|uniprotkb:mclA(gene name)|psi-mi:mclA(display_short)|uniprotkb:Regulator of SigE(gene name synonym)|uniprotkb:Sigma-E anti-sigma factor RseA(gene name synonym)|uniprotkb:Sigma-E factor negative regulatory protein(gene name synonym)|uniprotkb:rseA(gene name synonym)|uniprotkb:YPO2712(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864169|imex:IM-13779-6953	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000107186.17(gene)|ensembl:ENST00000319217.12(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0030425""(dendrite)|go:""GO:0045177""(apical part of cell)|go:""GO:0120192""(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|interpro:IPR051342|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:NP_003820.2|refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:XP_016870742.1|efo:""Orphanet:269505""|panther:PTHR19964(orthology-group)"	"interpro:IPR026279|interpro:IPR005573(Anti sigma-E protein RseA, C-terminal)|interpro:IPR005572(Anti sigma-E protein RseA, N-terminal)|go:""GO:0005886""(plasma membrane)|go:""GO:0016989""(sigma factor antagonist activity)|refseq:WP_002209673.1|interpro:IPR036147|refseq:YP_002347659.1|interpro:IPR052383"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606	rogid:LwZJGFoSTyhBT8PD/0j5gaZwEWc632	intact-crc:2D40F753FED462F5|rigid:5fkTX8m9Ke75yS42Gs3DztzwDR8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A7Y8RFP1	uniprotkb:Q00325	intact:EBI-2854011|uniprotkb:Q74VT1|uniprotkb:Q0WH27|uniprotkb:A0A0H2W345|uniprotkb:Q7CHJ5|uniprotkb:A0A384L578	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|uniprotkb:Q7Z7N7|uniprotkb:B3KS34|ensembl:ENSP00000228318.3|ensembl:ENSP00000447310.1	psi-mi:a0a7y8rfp1_yerpe(display_long)|uniprotkb:YPO1388(locus name)	psi-mi:s25a3_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Phosphate carrier protein, mitochondrial(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864183|imex:IM-13779-6952	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005594(YadA-like, C-terminal)|go:""GO:0009279""(cell outer membrane)|go:""GO:0009986""(cell surface)|refseq:YP_002346411.1|interpro:IPR045584"	"panther:PTHR45671(orthology-group)|ensembl:ENSG00000075415.15(gene)|ensembl:ENST00000228318.8(transcript)|ensembl:ENST00000551917.5(transcript)|go:""GO:0005315""(phosphate transmembrane transporter activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0015317""(""phosphate:proton symporter activity"")|go:""GO:0016020""(membrane)|go:""GO:0035435""(phosphate ion transmembrane transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990547""(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|efo:""Orphanet:91130"""	"psi-mi:""MI:0469""(intact)"	-	crc64:78714C85931B22D5	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:p3FK6eF6RqucVMsp7QfWajIkzjw632	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	intact-crc:A44EEC597291B18F|rigid:fLOk5sSCDmiaKYqlYkAboK4Z9Q8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARN5	uniprotkb:O75970	intact:EBI-2839967|uniprotkb:Q7CKL5|uniprotkb:Q74YZ9|uniprotkb:Q7ARK5|uniprotkb:Q7BTY3|uniprotkb:Q7BT06|uniprotkb:A0A1U8QKK8|uniprotkb:A0A3G5LBZ8|uniprotkb:A0A3G5L3F7	intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|uniprotkb:B2RTS3|ensembl:ENSP00000320006.7|intact:EBI-10961605	psi-mi:q7arn5_yerpe(display_long)|uniprotkb:ypmt1(gene name synonym)|uniprotkb:YPCD1.01(locus name)|uniprotkb:YPMT1.01(locus name)|uniprotkb:YPMT1.58c(locus name)|uniprotkb:YPPCP1.01(locus name)|uniprotkb:y1093(gene name)|psi-mi:y1093(display_short)|uniprotkb:YPO0031(locus name)|uniprotkb:YPO0171(locus name)|uniprotkb:YPO0249(locus name)|uniprotkb:YPO0386(locus name)|uniprotkb:YPO0528(locus name)|uniprotkb:YPO0567(locus name)|uniprotkb:YPO0637(locus name)|uniprotkb:YPO0780(locus name)|uniprotkb:YPO0826(locus name)|uniprotkb:YPO0924(locus name)|uniprotkb:YPO1013(locus name)|uniprotkb:YPO1086(locus name)|uniprotkb:YPO1132(locus name)|uniprotkb:YPO1338(locus name)|uniprotkb:YPO1427(locus name)|uniprotkb:YPO1520(locus name)|uniprotkb:YPO1623(locus name)|uniprotkb:YPO1692(locus name)|uniprotkb:YPO1729(locus name)|uniprotkb:YPO1750(locus name)|uniprotkb:YPO1900(locus name)|uniprotkb:YPO2026(locus name)|uniprotkb:YPO2085(locus name)|uniprotkb:YPO2178(locus name)|uniprotkb:YPO2365(locus name)|uniprotkb:YPO2396(locus name)|uniprotkb:YPO2516(locus name)|uniprotkb:YPO2643(locus name)|uniprotkb:YPO2721(locus name)|uniprotkb:YPO2808(locus name)|uniprotkb:YPO2932(locus name)|uniprotkb:YPO3209(locus name)|uniprotkb:YPO3251(locus name)|uniprotkb:YPO3282(locus name)|uniprotkb:YPO3434(locus name)|uniprotkb:YPO3542(locus name)|uniprotkb:YPO3591(locus name)|uniprotkb:YPO3701(locus name)|uniprotkb:YPO3756(locus name)|uniprotkb:YPO3774(locus name)|uniprotkb:YPO4010(locus name)	psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864176|imex:IM-13779-6951	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002348636.1|refseq:YP_002348652.1|refseq:YP_002348877.1|interpro:IPR017894|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:NP_395138.1|refseq:NP_395227.1|refseq:NP_395336.1|refseq:NP_395402.1|refseq:NP_857638.1|refseq:NP_857716.1|refseq:NP_857780.1|refseq:YP_094025.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR036397|refseq:WP_000255944.1|refseq:YP_006960969.1|go:""GO:0000150""(DNA strand exchange activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0015074""(DNA integration)|go:""GO:0032196""(transposition)|interpro:IPR006120(Resolvase, helix-turn-helix region)|refseq:YP_002345127.1|refseq:YP_002345256.1|refseq:YP_002345330.1|refseq:YP_002345463.1|refseq:YP_002345601.1|refseq:YP_002345638.1|refseq:YP_002345704.1|refseq:YP_002345836.1|refseq:YP_002345880.1|refseq:YP_002345972.1|refseq:YP_002346056.1|refseq:YP_002346129.1|refseq:YP_002346174.1|refseq:YP_002346362.1|refseq:YP_002346450.1|refseq:YP_002346536.1|refseq:YP_002346634.1|refseq:YP_002346730.1|refseq:YP_002346750.1|refseq:YP_002346890.1|refseq:YP_002347010.1|refseq:YP_002347066.1|refseq:YP_002347152.1|refseq:YP_002347332.1|refseq:YP_002347362.1|refseq:YP_002347480.1|refseq:YP_002347596.1|refseq:YP_002347668.1|refseq:YP_002347749.1|refseq:YP_002347862.1|refseq:YP_002348112.1|refseq:YP_002348152.1|refseq:YP_002348181.1|refseq:YP_002348326.1|refseq:YP_002348430.1|refseq:YP_002348476.1|refseq:YP_002346695.1|refseq:YP_002348583.1|panther:PTHR35004(orthology-group)"	"ensembl:ENSG00000107186.17(gene)|ensembl:ENST00000319217.12(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0030425""(dendrite)|go:""GO:0045177""(apical part of cell)|go:""GO:0120192""(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|interpro:IPR051342|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:NP_003820.2|refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:XP_016870742.1|efo:""Orphanet:269505""|panther:PTHR19964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gYoFpz6mpcJ4NYVEafsAkK14EIE632	rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606	intact-crc:E65572F3ED3D1E28|rigid:8pPsY8F+Sck/zeqAOiLXJQ0ldhQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15438	uniprotkb:A0A3G5L8A6	intact:EBI-2816276|uniprotkb:Q9UN52|uniprotkb:O95078|uniprotkb:O60265|uniprotkb:O75621|uniprotkb:O60922|uniprotkb:Q86X85|uniprotkb:O95290|uniprotkb:B2RPA9|uniprotkb:O95289|uniprotkb:D3DTX9|ensembl:ENSP00000285238.8	intact:EBI-2864155	psi-mi:mrp3_human(display_long)|uniprotkb:Multi-specific organic anion transporter D(gene name synonym)|uniprotkb:ABCC3(gene name)|psi-mi:ABCC3(display_short)|uniprotkb:CMOAT2(gene name synonym)|uniprotkb:MLP2(gene name synonym)|uniprotkb:MRP3(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 3(gene name synonym)|uniprotkb:Canalicular multispecific organic anion transporter 2(gene name synonym)	psi-mi:a0a3g5l8a6_yerpe(display_long)|uniprotkb:tadA(gene name)|psi-mi:tadA(display_short)|uniprotkb:y1307(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864152|imex:IM-13779-6954	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137542.1|refseq:NP_003777.2|ensembl:ENSG00000108846.16(gene)|ensembl:ENST00000285238.13(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0006855""(xenobiotic transmembrane transport)|go:""GO:0008559""(ABC-type xenobiotic transporter activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0015164""(glucuronoside transmembrane transporter activity)|go:""GO:0015431""(ABC-type glutathione S-conjugate transporter activity)|go:""GO:0015432""(ABC-type bile acid transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0042908""(xenobiotic transport)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|go:""GO:0043225""(ATPase-coupled inorganic anion transmembrane transporter activity)|go:""GO:0055085""(transmembrane transport)|go:""GO:0071714""(icosanoid transmembrane transporter activity)|go:""GO:0071716""(leukotriene transport)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:0150104""(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005292(""Multi drug resistance-associated protein (MRP)"")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR050173|mint:O15438|rcsb pdb:8HVH|rcsb pdb:8HW2|rcsb pdb:8HW4|rcsb pdb:8IZP|reactome:R-HSA-159418|reactome:R-HSA-382556|reactome:R-HSA-9749641|reactome:R-HSA-9753281|reactome:R-HSA-9818032|panther:PTHR24223(orthology-group)"	"go:""GO:0002100""(tRNA wobble adenosine to inosine editing)|go:""GO:0008270""(zinc ion binding)|go:""GO:0052717""(tRNA-specific adenosine-34 deaminase activity)|uniprotkb:A0A2U2GW10(uniprot-removed-ac)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR028883|refseq:WP_002211563.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:51ClxtQFDQ/6HAtrijoFeaZuDow9606	rogid:60cfwpZ8CVC4+Y4he/20/1k6Tes632	intact-crc:DD16E25D3870AB88|rigid:ZqSPUenCaRHmsBiO3C+8VnWeNn8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZU9	uniprotkb:O15438	intact:EBI-2841714	intact:EBI-2816276|uniprotkb:Q9UN52|uniprotkb:O95078|uniprotkb:O60265|uniprotkb:O75621|uniprotkb:O60922|uniprotkb:Q86X85|uniprotkb:O95290|uniprotkb:B2RPA9|uniprotkb:O95289|uniprotkb:D3DTX9|ensembl:ENSP00000285238.8	psi-mi:q8czu9_yerpe(display_long)|uniprotkb:y3342(locus name)	psi-mi:mrp3_human(display_long)|uniprotkb:Multi-specific organic anion transporter D(gene name synonym)|uniprotkb:ABCC3(gene name)|psi-mi:ABCC3(display_short)|uniprotkb:CMOAT2(gene name synonym)|uniprotkb:MLP2(gene name synonym)|uniprotkb:MRP3(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 3(gene name synonym)|uniprotkb:Canalicular multispecific organic anion transporter 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864162|imex:IM-13779-6950	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR002491(Periplasmic binding protein)|interpro:IPR050902	"refseq:NP_001137542.1|refseq:NP_003777.2|ensembl:ENSG00000108846.16(gene)|ensembl:ENST00000285238.13(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0006855""(xenobiotic transmembrane transport)|go:""GO:0008559""(ABC-type xenobiotic transporter activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0015164""(glucuronoside transmembrane transporter activity)|go:""GO:0015431""(ABC-type glutathione S-conjugate transporter activity)|go:""GO:0015432""(ABC-type bile acid transporter activity)|go:""GO:0015721""(bile acid and bile salt transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0042908""(xenobiotic transport)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|go:""GO:0043225""(ATPase-coupled inorganic anion transmembrane transporter activity)|go:""GO:0055085""(transmembrane transport)|go:""GO:0071714""(icosanoid transmembrane transporter activity)|go:""GO:0071716""(leukotriene transport)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:0150104""(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005292(""Multi drug resistance-associated protein (MRP)"")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR050173|mint:O15438|rcsb pdb:8HVH|rcsb pdb:8HW2|rcsb pdb:8HW4|rcsb pdb:8IZP|reactome:R-HSA-159418|reactome:R-HSA-382556|reactome:R-HSA-9749641|reactome:R-HSA-9753281|reactome:R-HSA-9818032|panther:PTHR24223(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:61Vn/X9ZzrY6cGaSgyM0HeClZVc632	rogid:51ClxtQFDQ/6HAtrijoFeaZuDow9606	intact-crc:776EEE2905EB1145|rigid:NXxlcO0UKFCH7dxr9elhXUOZL44	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O96007	uniprotkb:A0A6M0NFD2	intact:EBI-723640|uniprotkb:Q6IAI3|ensembl:ENSP00000380157.3	intact:EBI-2845236	psi-mi:moc2b_human(display_long)|uniprotkb:Molybdenum cofactor synthesis protein 2 large subunit(gene name synonym)|uniprotkb:Molybdopterin-synthase large subunit(gene name synonym)|uniprotkb:Molybdenum cofactor synthesis protein 2B(gene name synonym)|uniprotkb:MOCO1-B(gene name synonym)|uniprotkb:MOCS2(gene name)|psi-mi:MOCS2(display_short)|uniprotkb:MCBPE(gene name synonym)|uniprotkb:MOCO1(gene name synonym)	psi-mi:a0a6m0nfd2_yerpe(display_long)|uniprotkb:y2123(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864205|imex:IM-13779-6958	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164172.20(gene)|ensembl:ENST00000396954.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006777""(Mo-molybdopterin cofactor biosynthetic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0030366""(molybdopterin synthase activity)|go:""GO:0032324""(molybdopterin cofactor biosynthetic process)|go:""GO:1990140""(molybdopterin synthase complex)|interpro:IPR003448(Molybdopterin biosynthesis MoaE)|interpro:IPR028888|interpro:IPR036563|rcsb pdb:4AP8|rcsb pdb:5MPO|reactome:R-HSA-947581|refseq:NP_004522.1|efo:""Orphanet:308393""|panther:PTHR23404(orthology-group)"	interpro:IPR017030(Virulence effector, SrfC)|uniprotkb:A0A6B3SX50(uniprot-removed-ac)|refseq:WP_002223600.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/++dYHIJG1TsPULtnLVHgcvhuf49606	rogid:LSgmQHoXt7/pDPFzf/ovmUXx4gY632	intact-crc:66FADB24EAF81123|rigid:eJaK2BV3lprkYyJBQWKt7b6RsNE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96BY2	uniprotkb:A0A380PDY1	intact:EBI-739825|uniprotkb:Q9H833|uniprotkb:Q9HAS1|uniprotkb:B2RDF6|ensembl:ENSP00000298894.4|ensembl:ENSP00000451594.1|ensembl:ENSP00000482284.1|ensembl:ENSP00000486260.1	intact:EBI-2848416|uniprotkb:Q74UI0|uniprotkb:A0A0H2W558|uniprotkb:Q7CIW0|uniprotkb:A0A384L8E0	psi-mi:moap1_human(display_long)|uniprotkb:MOAP1(gene name)|psi-mi:MOAP1(display_short)|uniprotkb:PNMA4(gene name synonym)|uniprotkb:Paraneoplastic antigen Ma4(gene name synonym)	psi-mi:a0a380pdy1_yerpe(display_long)|uniprotkb:ogl(gene name)|psi-mi:ogl(display_short)|uniprotkb:YPO1713(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864231|imex:IM-13779-6959	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_071434.2|ensembl:ENSG00000165943.5(gene)|ensembl:ENSG00000278268.2(gene)|ensembl:ENST00000298894.5(transcript)|ensembl:ENST00000556883.1(transcript)|ensembl:ENST00000616515.2(transcript)|ensembl:ENST00000627896.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0051204""(protein insertion into mitochondrial membrane)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:2000786""(positive regulation of autophagosome assembly)|interpro:IPR026523|interpro:IPR048270|interpro:IPR048271|mint:Q96BY2|rcsb pdb:7LGC|dip:DIP-49959N|panther:PTHR23095(orthology-group)"	"interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027946|refseq:WP_002210841.1|go:""GO:0045490""(pectin catabolic process)|go:""GO:0047487""(oligogalacturonide lyase activity)|refseq:YP_002346716.1|panther:PTHR36842(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:wQSSosC82m35M8s+YamN1i73wi49606	rogid:e8mn+xTHxqbWMCnpEvzfGUD7MYI632	intact-crc:61124052DABED9C4|rigid:h9ncdV+5o94QHKI6IOlO+QgwWd4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3U7	uniprotkb:P69974	intact:EBI-358882|uniprotkb:A5D8U7|uniprotkb:A7E2Y0|uniprotkb:Q86TA2|uniprotkb:Q8N3I5|uniprotkb:Q8NAI0|uniprotkb:Q9UPW1|intact:EBI-2829603|intact:EBI-358896|uniprotkb:Q8NHE2|uniprotkb:B9EGP5|uniprotkb:F8VWA6|uniprotkb:F8W1Z6|intact:EBI-10962461|ensembl:ENSP00000377250.4	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	psi-mi:mon2_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)|uniprotkb:KIAA1040(gene name synonym)|uniprotkb:SF21(gene name synonym)|uniprotkb:Protein SF21(gene name synonym)	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864212|imex:IM-13779-6956	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001265399.1|refseq:NP_001265398.1|refseq:NP_055841.2|ensembl:ENSG00000061987.16(gene)|ensembl:ENST00000393630.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0015031""(protein transport)|go:""GO:0031901""(early endosome membrane)|go:""GO:0070062""(extracellular exosome)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032629|interpro:IPR032691|interpro:IPR032817|mint:Q7Z3U7|refseq:XP_016874530.1|panther:PTHR10663(orthology-group)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pEkENsLrswc7Cb2WTKZfQdESrtQ9606	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	intact-crc:D2A27E366095781B|rigid:36GykLN18v/ZtkLO91SsZhwYWU8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7L9L4	uniprotkb:A0A2S9PHG8	intact:EBI-2558745|uniprotkb:B2R8U6|uniprotkb:Q8IY23|uniprotkb:B4DRY3|ensembl:ENSP00000310189.3	intact:EBI-2864219|uniprotkb:Q74U49|uniprotkb:A0A0H2W3W1|uniprotkb:Q7CIC0|uniprotkb:A0A384LLU6	psi-mi:mob1b_human(display_long)|uniprotkb:MOB1B(gene name)|psi-mi:MOB1B(display_short)|uniprotkb:MOB4A(gene name synonym)|uniprotkb:MOBKL1A(gene name synonym)|uniprotkb:Mob1 homolog 1A(gene name synonym)|uniprotkb:Mob1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1A(gene name synonym)	psi-mi:a0a2s9phg8_yerpe(display_long)|uniprotkb:ntpA(gene name)|psi-mi:ntpA(display_short)|uniprotkb:nudB(gene name synonym)|uniprotkb:YPO2054(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864224|imex:IM-13779-6957	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_775739.1|refseq:NP_001231695.1|refseq:XP_005265766.1|ensembl:ENSG00000173542.9(gene)|ensembl:ENST00000309395.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0019209""(kinase activator activity)|go:""GO:0019900""(kinase binding)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0031952""(regulation of protein autophosphorylation)|go:""GO:0035329""(hippo signaling)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q7L9L4|reactome:R-HSA-2028269|panther:PTHR22599(orthology-group)"	"interpro:IPR003564(DATP pyrophosphohydrolase)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|refseq:WP_002211203.1|interpro:IPR051325|go:""GO:0004081""(""bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"")|go:""GO:0006167""(AMP biosynthetic process)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0008828""(dATP diphosphatase activity)|go:""GO:0019177""(dihydroneopterin triphosphate pyrophosphohydrolase activity)|go:""GO:0046656""(folic acid biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347036.1|panther:PTHR21340(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+OqB7l7K1Oax2Aj96idIAas4qT49606	rogid:kqA0Ubfi+HCJXMSeyp7ykpaa/XU632	intact-crc:256321E4F0229918|rigid:+p4WUcKzKnI6VGzXDxtz+mj5Zi8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P53985	uniprotkb:Q7CKV6	intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|ensembl:ENSP00000358640.4|ensembl:ENSP00000397106.2|ensembl:ENSP00000399104.2|ensembl:ENSP00000416167.2|ensembl:ENSP00000441065.1|ensembl:ENSP00000485688.1|ensembl:ENSP00000486000.1|ensembl:ENSP00000505879.1|uniprotkb:Q49A45	intact:EBI-2864190|uniprotkb:Q74R30	psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym)	psi-mi:ugpa_yerpe(display_long)|uniprotkb:ugpA(gene name)|psi-mi:ugpA(display_short)|uniprotkb:YPO3795(locus name)|uniprotkb:y0435(locus name)|uniprotkb:YP_3254(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864195|imex:IM-13779-6955	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000155380.13(gene)|ensembl:ENSG00000281917.4(gene)|ensembl:ENST00000369626.8(transcript)|ensembl:ENST00000429288.2(transcript)|ensembl:ENST00000443580.6(transcript)|ensembl:ENST00000458229.6(transcript)|ensembl:ENST00000538576.5(transcript)|ensembl:ENST00000628110.2(transcript)|ensembl:ENST00000630362.4(transcript)|ensembl:ENST00000679803.1(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007098""(centrosome cycle)|go:""GO:0008028""(monocarboxylic acid transmembrane transporter activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0015129""(lactate transmembrane transporter activity)|go:""GO:0015130""(mevalonate transmembrane transporter activity)|go:""GO:0015141""(succinate transmembrane transporter activity)|go:""GO:0015650""(""lactate:proton symporter activity"")|go:""GO:0015718""(monocarboxylic acid transport)|go:""GO:0015728""(mevalonate transport)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0030054""(cell junction)|go:""GO:0032094""(response to food)|go:""GO:0035879""(plasma membrane lactate transport)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042802""(identical protein binding)|go:""GO:0042867""(pyruvate catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0046943""(carboxylic acid transmembrane transporter activity)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0051780""(behavioral response to nutrient)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071407""(obsolete cellular response to organic cyclic compound)|go:""GO:0071422""(succinate transmembrane transport)|go:""GO:0097159""(obsolete organic cyclic compound binding)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1901475""(pyruvate transmembrane transport)|go:""GO:1905039""(carboxylic acid transmembrane transport)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|interpro:IPR050327|mint:P53985|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|rcsb pdb:7YR5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-9749641|refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|efo:""Orphanet:165991""|efo:""Orphanet:171690""|efo:""Orphanet:438075""|panther:PTHR11360(orthology-group)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_002211521.1|interpro:IPR050809|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|interpro:IPR035906|refseq:YP_002348672.1|panther:PTHR43227(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606	rogid:BcXGJnkZ9ahR1AUZUwM4eCb/hFA632	intact-crc:E8908410ECF2B303|rigid:wywWZCTelEXckC4GZniJfPXDVjA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14780	uniprotkb:A0A380PFG3	intact:EBI-1382326|uniprotkb:Q3LR70|uniprotkb:Q8N725|uniprotkb:Q9H4Z1|uniprotkb:B2R7V9|uniprotkb:Q9UCJ9|uniprotkb:Q9UCL1|uniprotkb:Q9UDK2|ensembl:ENSP00000361405.3	intact:EBI-2844399|uniprotkb:Q0WCT9|uniprotkb:Q7CJE7	psi-mi:mmp9_human(display_long)|uniprotkb:MMP9(gene name)|psi-mi:MMP9(display_short)|uniprotkb:CLG4B(gene name synonym)|uniprotkb:92 kDa type IV collagenase(gene name synonym)|uniprotkb:92 kDa gelatinase(gene name synonym)|uniprotkb:Gelatinase B(gene name synonym)	psi-mi:a0a380pfg3_yerpe(display_long)|uniprotkb:YPO2975(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864252|imex:IM-13779-6963	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100985.7(gene)|ensembl:ENST00000372330.3(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0006915""(apoptotic process)|go:""GO:0007566""(embryo implantation)|go:""GO:0008233""(peptidase activity)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016477""(cell migration)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030574""(collagen catabolic process)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0045742""(positive regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071492""(cellular response to UV-A)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0150077""(regulation of neuroinflammatory response)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904645""(response to amyloid-beta)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000697""(negative regulation of epithelial cell differentiation involved in kidney development)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|go:""GO:2001258""(negative regulation of cation channel activity)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036375|interpro:IPR036943|mint:P14780|rcsb pdb:1GKC|rcsb pdb:1GKD|rcsb pdb:1ITV|rcsb pdb:1L6J|rcsb pdb:2OVX|rcsb pdb:2OVZ|rcsb pdb:2OW0|rcsb pdb:2OW1|rcsb pdb:2OW2|rcsb pdb:4H1Q|rcsb pdb:4H2E|rcsb pdb:4H3X|rcsb pdb:4H82|rcsb pdb:4HMA|rcsb pdb:4JIJ|rcsb pdb:4JQG|rcsb pdb:4WZV|rcsb pdb:4XCT|rcsb pdb:5CUH|rcsb pdb:5I12|rcsb pdb:5TH6|rcsb pdb:5TH9|rcsb pdb:5UE3|rcsb pdb:5UE4|rcsb pdb:6ESM|rcsb pdb:8K5V|rcsb pdb:8K5W|rcsb pdb:8K5X|rcsb pdb:8K5Y|reactome:R-HSA-1433557|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-2022090|reactome:R-HSA-3928665|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-9009391|refseq:NP_004985.2|dip:DIP-29518N|panther:PTHR10201(orthology-group)|efo:""Orphanet:1040"""	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002211613.1|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:YP_002347899.1|interpro:IPR050881|panther:PTHR42832(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0PnzH1KPp4SKRWfRGotPA2eSHZk9606	rogid:gxs4oIww4YLZ4JkmmT+hmD0ULQM632	intact-crc:63C5009BFDBE5D71|rigid:xKY0PNB/trEZKUrwJmpAlLT5ROw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZE38	uniprotkb:P24844	intact:EBI-2864269|uniprotkb:Q0WEH4	intact:EBI-716193|uniprotkb:Q9BQL9|uniprotkb:Q9BUF9|uniprotkb:Q9H136|uniprotkb:E1P5T6|ensembl:ENSP00000279022.2	psi-mi:y2347_yerpe(display_long)|uniprotkb:YPO2347(locus name)|uniprotkb:y1985(locus name)|uniprotkb:YP_2134(locus name)	psi-mi:myl9_human(display_long)|uniprotkb:Myosin regulatory light chain 9(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC1(gene name synonym)|uniprotkb:Myosin regulatory light chain 2, smooth muscle isoform(gene name synonym)|uniprotkb:Myosin RLC(gene name synonym)|uniprotkb:MLC-2C(gene name synonym)|uniprotkb:20 kDa myosin light chain(gene name synonym)|uniprotkb:MYL9(gene name)|psi-mi:MYL9(display_short)|uniprotkb:MRLC1(gene name synonym)|uniprotkb:MYRL2(gene name synonym)|uniprotkb:MLC2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864266|imex:IM-13779-6962	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021147|interpro:IPR006507(Conserved hypothetical protein CHP01620)|go:""GO:0005886""(plasma membrane)|refseq:WP_002210980.1|refseq:YP_002347314.1|panther:PTHR39342(orthology-group)"	"refseq:NP_006088.2|refseq:NP_852667.1|dip:DIP-60525N|ensembl:ENSG00000101335.10(gene)|ensembl:ENST00000279022.7(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005859""(muscle myosin complex)|go:""GO:0005938""(cell cortex)|go:""GO:0006937""(regulation of muscle contraction)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0030016""(myofibril)|go:""GO:0030018""(Z disc)|go:""GO:0030239""(myofibril assembly)|go:""GO:0032036""(myosin heavy chain binding)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0070527""(platelet aggregation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR050403|mint:P24844|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-8936459|panther:PTHR23049(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/20	rogid:5b/hYxThUsz9xm/OryDxbWpC+Ag632	rogid:FeJb0ac0n3hkVmRDnxeGSlL2/A89606	intact-crc:0BF12442C4BED68E|rigid:7QErqAZ9fRN9f6LACQVwfRf9akU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08253	uniprotkb:Q8ZH37	intact:EBI-1033518|ensembl:ENSP00000219070.4|uniprotkb:B2R6U1|uniprotkb:Q9UCJ8|uniprotkb:E9PE45|uniprotkb:B4DWH3	intact:EBI-2851027|uniprotkb:Q0WHX0|uniprotkb:Q7CH28|uniprotkb:Q74S62	psi-mi:mmp2_human(display_long)|uniprotkb:MMP2(gene name)|psi-mi:MMP2(display_short)|uniprotkb:CLG4A(gene name synonym)|uniprotkb:72 kDa gelatinase(gene name synonym)|uniprotkb:Matrix metalloproteinase-2(gene name synonym)|uniprotkb:Gelatinase A(gene name synonym)|uniprotkb:TBE-1(gene name synonym)	psi-mi:gmhbb_yerpe(display_long)|uniprotkb:gmhB(gene name)|psi-mi:gmhB(display_short)|uniprotkb:D,D-heptose 1,7-bisphosphate phosphatase(gene name synonym)|uniprotkb:YPO1074(locus name)|uniprotkb:YP_2775(locus name)|uniprotkb:y3103(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864259|imex:IM-13779-6961	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000087245.13(gene)|ensembl:ENST00000219070.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0001542""(ovulation from ovarian follicle)|go:""GO:0001553""(luteinization)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001955""(blood vessel maturation)|go:""GO:0001957""(intramembranous ossification)|go:""GO:0001968""(fibronectin binding)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007507""(heart development)|go:""GO:0007566""(embryo implantation)|go:""GO:0007567""(parturition)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0014012""(peripheral nervous system axon regeneration)|go:""GO:0014823""(response to activity)|go:""GO:0016477""(cell migration)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030017""(sarcomere)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030574""(collagen catabolic process)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0034614""(cellular response to reactive oxygen species)|go:""GO:0035094""(response to nicotine)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0043627""(response to estrogen)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0048771""(tissue remodeling)|go:""GO:0051602""(response to electrical stimulus)|go:""GO:0055093""(response to hyperoxia)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060346""(bone trabecula formation)|go:""GO:0060740""(prostate gland epithelium morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071492""(cellular response to UV-A)|go:""GO:0071498""(cellular response to fluid shear stress)|go:""GO:1903378""(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:""GO:1904645""(response to amyloid-beta)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036375|interpro:IPR036943|mint:P08253|rcsb pdb:1CK7|rcsb pdb:1CXW|rcsb pdb:1EAK|rcsb pdb:1GEN|rcsb pdb:1GXD|rcsb pdb:1HOV|rcsb pdb:1J7M|rcsb pdb:1KS0|rcsb pdb:1QIB|rcsb pdb:1RTG|rcsb pdb:3AYU|rcsb pdb:7XGJ|rcsb pdb:7XJO|rcsb pdb:8H78|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-381426|reactome:R-HSA-3928665|reactome:R-HSA-6785807|reactome:R-HSA-9009391|refseq:NP_001121363.1|refseq:NP_001289437.1|refseq:NP_001289438.1|refseq:NP_001289439.1|refseq:NP_004521.1|efo:""Orphanet:371428""|panther:PTHR10201(orthology-group)"	"interpro:IPR023214|interpro:IPR006549(HAD-superfamily hydrolase, subfamily IIIA)|interpro:IPR004446(Histidinol phosphatase-related protein)|interpro:IPR006543(Histidinol-phosphate phosphatase)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009244""(lipopolysaccharide core region biosynthetic process)|go:""GO:0034200""(D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity)|go:""GO:0097171""(ADP-L-glycero-beta-D-manno-heptose biosynthetic process)|interpro:IPR036412|refseq:WP_002220062.1|refseq:YP_002346118.1|panther:PTHR42891(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:s0IHoSkzT9GNfkkLZsVsV7cIf1g9606	rogid:TQJisFcuEi2sCw0MeU57QEi79XA632	intact-crc:1E8EA8699206D2F4|rigid:igrNty+l/GBVxD15iubL9Y83h1A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VAF6	uniprotkb:Q96T76	intact:EBI-2841984	intact:EBI-1044169|uniprotkb:Q9BYS9|uniprotkb:Q17RZ8|uniprotkb:Q5T455|uniprotkb:Q66K82|uniprotkb:Q7L4W8|uniprotkb:Q969Z1|uniprotkb:Q96DF1|uniprotkb:Q96MR1|uniprotkb:Q96RK5|uniprotkb:Q96SK1|uniprotkb:Q9BUE2|uniprotkb:D3DR55|uniprotkb:B0QZ75|uniprotkb:B3KPE5|uniprotkb:B4DQX2|uniprotkb:B4E2I3|uniprotkb:F8W9Y2|ensembl:ENSP00000359818.1|ensembl:ENSP00000412698.2	psi-mi:a0a6b3vaf6_yerpe(display_long)|uniprotkb:NCTC5923_02288(orf name)|uniprotkb:y3253(locus name)	psi-mi:mms19_human(display_long)|uniprotkb:MMS19(gene name)|psi-mi:MMS19(display_short)|uniprotkb:MMS19L(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864245|imex:IM-13779-6960	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A6B3SX19(uniprot-removed-ac)|interpro:IPR021488|refseq:WP_002209913.1	"refseq:NP_071757.4|refseq:NP_001276332.1|refseq:NP_001276333.1|refseq:NP_001276334.1|refseq:NP_001317057.1|refseq:XP_016872013.1|ensembl:ENSG00000155229.21(gene)|ensembl:ENST00000370782.6(transcript)|ensembl:ENST00000438925.7(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005675""(transcription factor TFIIH holo complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0007059""(chromosome segregation)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0071817""(MMXD complex)|go:""GO:0097361""(cytosolic [4Fe-4S] assembly targeting complex)|go:""GO:0097428""(obsolete protein maturation by iron-sulfur cluster transfer)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|mint:Q96T76|reactome:R-HSA-2564830|panther:PTHR12891(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EyZ3xSVIurU4RgAtisPOLX4IdPw632	rogid:sujw9MQiwau6A0dumVM7gXVMGjE9606	intact-crc:D0B62938345EF0C0|rigid:BOK9uZLDiWT56bUYWLMiqe8CJ24	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15014	uniprotkb:A0A380PL37	intact:EBI-399257|uniprotkb:B3KP92|uniprotkb:Q567V0|uniprotkb:Q8J026|uniprotkb:D3DXA5|ensembl:ENSP00000353643.1|ensembl:ENSP00000391969.2|ensembl:ENSP00000410532.1|ensembl:ENSP00000415476.2	intact:EBI-2848428|uniprotkb:Q74PX4|uniprotkb:A0A0H2W7W6|uniprotkb:Q7CG52|uniprotkb:A0A384KFS5	psi-mi:mo4l2_human(display_long)|uniprotkb:MORF4L2(gene name)|psi-mi:MORF4L2(display_short)|uniprotkb:KIAA0026(gene name synonym)|uniprotkb:MRGX(gene name synonym)|uniprotkb:MORF-related gene X protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRGX(gene name synonym)|uniprotkb:Protein MSL3-2(gene name synonym)	psi-mi:a0a380pl37_yerpe(display_long)|uniprotkb:YPO0421(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864238|imex:IM-13779-6964	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001135894.1|refseq:NP_001135895.1|refseq:NP_001135896.1|refseq:NP_001135897.1|refseq:NP_001135898.1|refseq:NP_001135899.1|refseq:NP_001135900.1|refseq:NP_001135901.1|refseq:NP_001135902.1|refseq:NP_001135903.1|refseq:NP_001135904.1|refseq:NP_036418.1|refseq:NP_001135890.1|refseq:NP_001135891.1|refseq:NP_001135892.1|refseq:NP_001135893.1|ensembl:ENSG00000123562.18(gene)|ensembl:ENST00000360458.5(transcript)|ensembl:ENST00000433176.6(transcript)|ensembl:ENST00000441076.7(transcript)|ensembl:ENST00000451301.5(transcript)|go:""GO:0000786""(nucleosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006325""(chromatin organization)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051155""(positive regulation of striated muscle cell differentiation)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000779""(regulation of double-strand break repair)|interpro:IPR008676(MRG)|interpro:IPR026541|interpro:IPR038217|mint:Q15014|reactome:R-HSA-3214847|panther:PTHR10880(orthology-group)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR027463|refseq:WP_002209200.1|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:YP_002345497.1|panther:PTHR32063(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7SlnJWNVhfdzirTHBEseWbJQjyU9606	rogid:eNynpfVNIWDaaydEc5eAanQErH8632	intact-crc:BB1C996FDE234130|rigid:AEHyu0SfCDPT1ykcb5gfsRalFok	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZY2	uniprotkb:P40692	intact:EBI-2847648	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790.3	psi-mi:q8czy2_yerpe(display_long)|uniprotkb:recC(gene name)|psi-mi:recC(display_short)|uniprotkb:Exonuclease V subunit RecC(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecC(gene name synonym)|uniprotkb:y3166(locus name)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864313|imex:IM-13779-6969	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002231332.1|interpro:IPR006697(Exodeoxyribonuclease V, RecC subunit)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0004519""(endonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR041500"	"efo:""Orphanet:144""|efo:""Orphanet:252202""|ensembl:ENSG00000076242.18(gene)|ensembl:ENST00000231790.8(transcript)|go:""GO:0000289""(""nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0000712""(resolution of meiotic recombination intermediates)|go:""GO:0000795""(synaptonemal complex)|go:""GO:0001673""(male germ cell nucleus)|go:""GO:0003682""(chromatin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005712""(chiasma)|go:""GO:0005715""(late recombination nodule)|go:""GO:0006298""(mismatch repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0007060""(male meiosis chromosome segregation)|go:""GO:0007129""(homologous chromosome pairing at meiosis)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009617""(response to bacterium)|go:""GO:0016020""(membrane)|go:""GO:0016321""(female meiosis chromosome segregation)|go:""GO:0016446""(somatic hypermutation of immunoglobulin genes)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0032137""(guanine/thymine mispair binding)|go:""GO:0032389""(MutLalpha complex)|go:""GO:0043060""(meiotic metaphase I homologous chromosome alignment)|go:""GO:0045141""(meiotic telomere clustering)|go:""GO:0045190""(isotype switching)|go:""GO:0045950""(negative regulation of mitotic recombination)|go:""GO:0048298""(positive regulation of isotype switching to IgA isotypes)|go:""GO:0048304""(positive regulation of isotype switching to IgG isotypes)|go:""GO:0048477""(oogenesis)|go:""GO:0051257""(meiotic spindle midzone assembly)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|rcsb pdb:6WBA|rcsb pdb:6WBB|rcsb pdb:6WBC|rcsb pdb:7M60|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446|refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|refseq:XP_005265220.1|refseq:XP_005265221.1|dip:DIP-27601N|panther:PTHR10073(orthology-group)|ensembl:ENSP00000231790.3|ensembl:ENST00000429117.6|ensembl:ENSP00000407019.2|ensembl:ENST00000435176.5|ensembl:ENSP00000402564.1|ensembl:ENST00000455445.6|ensembl:ENSP00000398272.2|ensembl:ENST00000458205.6|ensembl:ENSP00000402667.2|ensembl:ENST00000466900.6|ensembl:ENSP00000519069.1|ensembl:ENST00000485889.2|ensembl:ENSP00000518946.1|ensembl:ENST00000492474.6|ensembl:ENSP00000518393.1|ensembl:ENST00000536378.5|ensembl:ENSP00000444286.2|ensembl:ENST00000539477.6|ensembl:ENSP00000443665.1|ensembl:ENST00000674019.1|ensembl:ENSP00000501081.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:2Q4GsXvIqa5TrZjFD/kPigwGJNw632	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	intact-crc:82C01BE16C1C2412|rigid:bYcFZFVywWvpZmwhgkiiFKoxnFc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NEZ4	uniprotkb:A0A7Y8RC16	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189.6	intact:EBI-2843188|uniprotkb:Q74PV7|uniprotkb:A0A0H2W7X5|uniprotkb:Q7CG44|uniprotkb:Q0WJQ7|uniprotkb:A0A384KPQ0	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:a0a7y8rc16_yerpe(display_long)|uniprotkb:YPO0404(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864295|imex:IM-13779-6966	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:261652""|dip:DIP-48649N|ensembl:ENSG00000055609.21(gene)|ensembl:ENST00000262189.11(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042054""(histone methyltransferase activity)|go:""GO:0042800""(histone H3K4 methyltransferase activity)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051602""(response to electrical stimulus)|go:""GO:0140945""(histone H3K4 monomethyltransferase activity)|go:""GO:0140999""(histone H3K4 trimethyltransferase activity)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|interpro:IPR046341|interpro:IPR047003|interpro:IPR047004|interpro:IPR047005|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|rcsb pdb:7W6L|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922|refseq:NP_733751.2|panther:PTHR45888(orthology-group)"	"interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR006327(Phosphotransferase system, fructose IIC component)|interpro:IPR013014(Phosphotransferase system, EIIC component, type 2)|go:""GO:0005351""(""carbohydrate:proton symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|refseq:YP_002345481.1|interpro:IPR050864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/10	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	rogid:SLkzxzvdatLCfveYdH0UaKifvHU632	intact-crc:1E94B5BEC4464416|rigid:pJ8WfYrXxbJrM9IWT9RugNd3Vt8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GVX8	uniprotkb:P24844	intact:EBI-2864277|uniprotkb:Q74U22|uniprotkb:Q0WF66|uniprotkb:Q7CID4|uniprotkb:A0A384LJV4	intact:EBI-716193|uniprotkb:Q9BQL9|uniprotkb:Q9BUF9|uniprotkb:Q9H136|uniprotkb:E1P5T6|ensembl:ENSP00000279022.2	psi-mi:a0a2u2gvx8_yerpe(display_long)|uniprotkb:YPO2090(locus name)	psi-mi:myl9_human(display_long)|uniprotkb:Myosin regulatory light chain 9(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC1(gene name synonym)|uniprotkb:Myosin regulatory light chain 2, smooth muscle isoform(gene name synonym)|uniprotkb:Myosin RLC(gene name synonym)|uniprotkb:MLC-2C(gene name synonym)|uniprotkb:20 kDa myosin light chain(gene name synonym)|uniprotkb:MYL9(gene name)|psi-mi:MYL9(display_short)|uniprotkb:MRLC1(gene name synonym)|uniprotkb:MYRL2(gene name synonym)|uniprotkb:MLC2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864281|imex:IM-13779-6965	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008713(Bacteriophage Lambda NinG)|mint:A0A2U2GVX8|refseq:WP_002211735.1|refseq:YP_002347072.1	"refseq:NP_006088.2|refseq:NP_852667.1|dip:DIP-60525N|ensembl:ENSG00000101335.10(gene)|ensembl:ENST00000279022.7(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005859""(muscle myosin complex)|go:""GO:0005938""(cell cortex)|go:""GO:0006937""(regulation of muscle contraction)|go:""GO:0008307""(structural constituent of muscle)|go:""GO:0030016""(myofibril)|go:""GO:0030018""(Z disc)|go:""GO:0030239""(myofibril assembly)|go:""GO:0032036""(myosin heavy chain binding)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0070527""(platelet aggregation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR050403|mint:P24844|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-8936459|panther:PTHR23049(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/20	rogid:NfYXK1H8rOYnW6x1pX4uF9a1Ztk632	rogid:FeJb0ac0n3hkVmRDnxeGSlL2/A89606	intact-crc:DC2DC0D728914491|rigid:TM/WuR9/neRMkt485JoHardvgKY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAA1	uniprotkb:P19105	intact:EBI-2860122|uniprotkb:Q74RC5|uniprotkb:Q8D1L7|uniprotkb:Q0WAA3	intact:EBI-354418|ensembl:ENSP00000217652.3|ensembl:ENSP00000441231.1|ensembl:ENSP00000462171.1|ensembl:ENSP00000463614.1|uniprotkb:Q53X45	psi-mi:btub_yerpe(display_long)|uniprotkb:btuB(gene name)|psi-mi:btuB(display_short)|uniprotkb:Cobalamin receptor(gene name synonym)|uniprotkb:Outer membrane cobalamin translocator(gene name synonym)|uniprotkb:YPO3910(locus name)|uniprotkb:y0325(locus name)|uniprotkb:YP_3138(locus name)	psi-mi:ml12a_human(display_long)|uniprotkb:MYL12A(gene name)|psi-mi:MYL12A(display_short)|uniprotkb:RLC(gene name synonym)|uniprotkb:MLCB(gene name synonym)|uniprotkb:Myosin regulatory light chain 2, nonsarcomeric(gene name synonym)|uniprotkb:Myosin RLC(gene name synonym)|uniprotkb:MLC-2B(gene name synonym)|uniprotkb:MRLC3(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC3(gene name synonym)|uniprotkb:Epididymis secretory protein Li 24(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864288|imex:IM-13779-6968	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010101(TonB-dependent vitamin B12 receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR039426|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0015420""(ABC-type vitamin B12 transporter activity)|go:""GO:0015889""(cobalamin transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0046930""(pore complex)|interpro:IPR036942|interpro:IPR037066|refseq:WP_002228170.1|panther:PTHR30069(orthology-group)"	"refseq:NP_006462.1|ensembl:ENSG00000101608.13(gene)|ensembl:ENST00000217652.8(transcript)|ensembl:ENST00000536605.1(transcript)|ensembl:ENST00000578611.5(transcript)|ensembl:ENST00000579226.5(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016460""(myosin II complex)|go:""GO:0030018""(Z disc)|go:""GO:0035254""(glutamate receptor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|interpro:IPR050403|mint:P19105|reactome:R-HSA-3928664|reactome:R-HSA-445355|refseq:NP_001289976.1|refseq:NP_001289977.1|refseq:NP_001289978.1|panther:PTHR23049(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DOy5Ti+yMtG0ogW80Av35K2fKW0632	rogid:Q1Uv36YgdA5rMmMOyX5+3rKKho09606	intact-crc:2E5767B6DECBB39D|rigid:FqbF+MxtYxS8Tlkl2DcSyAAJyro	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GXB4	uniprotkb:Q8NEZ4	intact:EBI-2864305|uniprotkb:A0A0H2W862|uniprotkb:Q3V8F5|uniprotkb:A0A384L2Y1|uniprotkb:Q0WIX0	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189.6	psi-mi:a0a2u2gxb4_yerpe(display_long)|uniprotkb:flhB(gene name)|psi-mi:flhB(display_short)|uniprotkb:YPO0706(locus name)	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864302|imex:IM-13779-6967	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029025|interpro:IPR006136(Flagellar biosynthetic protein FlhB)|interpro:IPR006135(Type III secretion exporter)|refseq:WP_002211451.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|go:""GO:0044780""(bacterial-type flagellum assembly)|refseq:YP_002345768.1"	"efo:""Orphanet:261652""|dip:DIP-48649N|ensembl:ENSG00000055609.21(gene)|ensembl:ENST00000262189.11(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042054""(histone methyltransferase activity)|go:""GO:0042800""(histone H3K4 methyltransferase activity)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051602""(response to electrical stimulus)|go:""GO:0140945""(histone H3K4 monomethyltransferase activity)|go:""GO:0140999""(histone H3K4 trimethyltransferase activity)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|interpro:IPR046341|interpro:IPR047003|interpro:IPR047004|interpro:IPR047005|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|rcsb pdb:7W6L|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922|refseq:NP_733751.2|panther:PTHR45888(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/10	rogid:5HXMZCcZciifIqMkObQl6cm1StE632	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	intact-crc:0CE7080B81C2DB52|rigid:FvrgGTg/Mdt55D+LanjIjGmYWc4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P68587	uniprotkb:Q15773	intact:EBI-2844901|uniprotkb:P40295	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630.5|ensembl:ENSP00000403941.1|ensembl:ENSP00000446317.1	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864320|imex:IM-13779-6974	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"refseq:NP_005430.1|ensembl:ENSG00000089693.11(gene)|ensembl:ENST00000203630.10(transcript)|ensembl:ENST00000435120.5(transcript)|ensembl:ENST00000539187.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016020""(membrane)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR019376|mint:Q15773|panther:PTHR13105(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	intact-crc:B335218A112471B5|rigid:kj+5gU1doIg0cq7vysZzgmiq/R0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBC2	uniprotkb:Q16539	intact:EBI-2851492|uniprotkb:Q0WBF3	intact:EBI-73946|uniprotkb:A8K6P4|uniprotkb:B0LPH0|uniprotkb:A6ZJ92|uniprotkb:O60776|uniprotkb:Q13083|uniprotkb:Q14084|uniprotkb:Q8TDX0|uniprotkb:B5TY32|ensembl:ENSP00000229794.4	psi-mi:if2_yerpe(display_long)|uniprotkb:infB(gene name)|psi-mi:infB(display_short)|uniprotkb:YPO3496(locus name)|uniprotkb:y0688(locus name)|uniprotkb:YP_0587(locus name)	psi-mi:mk14_human(display_long)|uniprotkb:Mitogen-activated protein kinase p38 alpha(gene name synonym)|uniprotkb:Cytokine suppressive anti-inflammatory drug-binding protein(gene name synonym)|uniprotkb:MAX-interacting protein 2(gene name synonym)|uniprotkb:MAP kinase MXI2(gene name synonym)|uniprotkb:SAPK2A(gene name synonym)|uniprotkb:MAPK14(gene name)|psi-mi:MAPK14(display_short)|uniprotkb:CSBP(gene name synonym)|uniprotkb:CSBP1(gene name synonym)|uniprotkb:CSBP2(gene name synonym)|uniprotkb:CSPB1(gene name synonym)|uniprotkb:MXI2(gene name synonym)|uniprotkb:Stress-activated protein kinase 2a(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864360|imex:IM-13779-6972	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002223151.1|interpro:IPR044145|interpro:IPR009061(Putative DNA binding)|interpro:IPR013575(Initiation factor 2 associated region, bacterial)|interpro:IPR006847(Translation initiation factor IF-2, N-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000178(Initiation factor 2)|interpro:IPR023115|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR015760(Translation initiation factor 2 related)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR036925|interpro:IPR053905|refseq:YP_002348385.1|panther:PTHR43381(orthology-group)"	"refseq:NP_001306.1|refseq:NP_620581.1|refseq:NP_620582.1|refseq:NP_620583.1|panther:PTHR24055(orthology-group)|dip:DIP-30987N|ensembl:ENSG00000112062.13(gene)|ensembl:ENST00000229794.9(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0000922""(spindle pole)|go:""GO:0001502""(cartilage condensation)|go:""GO:0001525""(angiogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001890""(placenta development)|go:""GO:0002021""(response to dietary excess)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0004708""(MAP kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007178""(cell surface receptor protein serine/threonine kinase signaling pathway)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010831""(positive regulation of myotube differentiation)|go:""GO:0016607""(nuclear speck)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019395""(fatty acid oxidation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030168""(platelet activation)|go:""GO:0030278""(regulation of ossification)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0031098""(stress-activated protein kinase signaling cascade)|go:""GO:0031281""(positive regulation of cyclase activity)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032868""(response to insulin)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046323""(D-glucose import)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048273""(mitogen-activated protein kinase p38 binding)|go:""GO:0048863""(stem cell differentiation)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051525""(NFAT protein binding)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060348""(bone development)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0071493""(cellular response to UV-B)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0090336""(positive regulation of brown fat cell differentiation)|go:""GO:0090398""(cellular senescence)|go:""GO:0090400""(stress-induced premature senescence)|go:""GO:0098586""(cellular response to virus)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099179""(regulation of synaptic membrane adhesion)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1900015""(regulation of cytokine production involved in inflammatory response)|go:""GO:1901741""(positive regulation of myoblast fusion)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038784|interpro:IPR050117|mint:Q16539|rcsb pdb:1A9U|rcsb pdb:1BL6|rcsb pdb:1BL7|rcsb pdb:1BMK|rcsb pdb:1DI9|rcsb pdb:1IAN|rcsb pdb:1KV1|rcsb pdb:1KV2|rcsb pdb:1M7Q|rcsb pdb:1OUK|rcsb pdb:1OUY|rcsb pdb:1OVE|rcsb pdb:1OZ1|rcsb pdb:1R39|rcsb pdb:1R3C|rcsb pdb:1W7H|rcsb pdb:1W82|rcsb pdb:1W83|rcsb pdb:1W84|rcsb pdb:1WBN|rcsb pdb:1WBO|rcsb pdb:1WBS|rcsb pdb:1WBT|rcsb pdb:1WBV|rcsb pdb:1WBW|rcsb pdb:1WFC|rcsb pdb:1YQJ|rcsb pdb:1ZYJ|rcsb pdb:1ZZ2|rcsb pdb:1ZZL|rcsb pdb:2BAJ|rcsb pdb:2BAK|rcsb pdb:2BAL|rcsb pdb:2BAQ|rcsb pdb:2FSL|rcsb pdb:2FSM|rcsb pdb:2FSO|rcsb pdb:2FST|rcsb pdb:2GFS|rcsb pdb:2I0H|rcsb pdb:2LGC|rcsb pdb:2NPQ|rcsb pdb:2OKR|rcsb pdb:2ONL|rcsb pdb:2QD9|rcsb pdb:2RG5|rcsb pdb:2RG6|rcsb pdb:2Y8O|rcsb pdb:2YIS|rcsb pdb:2YIW|rcsb pdb:2YIX|rcsb pdb:2ZAZ|rcsb pdb:2ZB0|rcsb pdb:2ZB1|rcsb pdb:3BV2|rcsb pdb:3BV3|rcsb pdb:3BX5|rcsb pdb:3C5U|rcsb pdb:3CTQ|rcsb pdb:3D7Z|rcsb pdb:3D83|rcsb pdb:3DS6|rcsb pdb:3DT1|rcsb pdb:3E92|rcsb pdb:3E93|rcsb pdb:3FC1|rcsb pdb:3FI4|rcsb pdb:3FKL|rcsb pdb:3FKN|rcsb pdb:3FKO|rcsb pdb:3FL4|rcsb pdb:3FLN|rcsb pdb:3FLQ|rcsb pdb:3FLS|rcsb pdb:3FLW|rcsb pdb:3FLY|rcsb pdb:3FLZ|rcsb pdb:3FMH|rcsb pdb:3FMJ|rcsb pdb:3FMK|rcsb pdb:3FML|rcsb pdb:3FMM|rcsb pdb:3FMN|rcsb pdb:3FSF|rcsb pdb:3FSK|rcsb pdb:3GC7|rcsb pdb:3GCP|rcsb pdb:3GCQ|rcsb pdb:3GCS|rcsb pdb:3GCU|rcsb pdb:3GCV|rcsb pdb:3GFE|rcsb pdb:3GI3|rcsb pdb:3HA8|rcsb pdb:3HEC|rcsb pdb:3HEG|rcsb pdb:3HL7|rcsb pdb:3HLL|rcsb pdb:3HP2|rcsb pdb:3HP5|rcsb pdb:3HRB|rcsb pdb:3HUB|rcsb pdb:3HUC|rcsb pdb:3HV3|rcsb pdb:3HV4|rcsb pdb:3HV5|rcsb pdb:3HV6|rcsb pdb:3HV7|rcsb pdb:3HVC|rcsb pdb:3IPH|rcsb pdb:3ITZ|rcsb pdb:3IW5|rcsb pdb:3IW6|rcsb pdb:3IW7|rcsb pdb:3IW8|rcsb pdb:3K3I|rcsb pdb:3K3J|rcsb pdb:3KF7|rcsb pdb:3KQ7|rcsb pdb:3L8S|rcsb pdb:3L8X|rcsb pdb:3LFA|rcsb pdb:3LFB|rcsb pdb:3LFC|rcsb pdb:3LFD|rcsb pdb:3LFE|rcsb pdb:3LFF|rcsb pdb:3LHJ|rcsb pdb:3MGY|rcsb pdb:3MH0|rcsb pdb:3MH1|rcsb pdb:3MH2|rcsb pdb:3MH3|rcsb pdb:3MPA|rcsb pdb:3MPT|rcsb pdb:3MVL|rcsb pdb:3MVM|rcsb pdb:3MW1|rcsb pdb:3NEW|rcsb pdb:3NNU|rcsb pdb:3NNV|rcsb pdb:3NNW|rcsb pdb:3NNX|rcsb pdb:3NWW|rcsb pdb:3O8P|rcsb pdb:3O8T|rcsb pdb:3O8U|rcsb pdb:3OBG|rcsb pdb:3OBJ|rcsb pdb:3OC1|rcsb pdb:3OCG|rcsb pdb:3OD6|rcsb pdb:3ODY|rcsb pdb:3ODZ|rcsb pdb:3OEF|rcsb pdb:3PG3|rcsb pdb:3QUD|rcsb pdb:3QUE|rcsb pdb:3RIN|rcsb pdb:3ROC|rcsb pdb:3S3I|rcsb pdb:3S4Q|rcsb pdb:3U8W|rcsb pdb:3UVP|rcsb pdb:3UVQ|rcsb pdb:3UVR|rcsb pdb:3ZS5|rcsb pdb:3ZSG|rcsb pdb:3ZSH|rcsb pdb:3ZSI|rcsb pdb:3ZYA|rcsb pdb:4A9Y|rcsb pdb:4AA0|rcsb pdb:4AA4|rcsb pdb:4AA5|rcsb pdb:4AAC|rcsb pdb:4DLI|rcsb pdb:4DLJ|rcsb pdb:4E5A|rcsb pdb:4E5B|rcsb pdb:4E6A|rcsb pdb:4E6C|rcsb pdb:4E8A|rcsb pdb:4EH2|rcsb pdb:4EH3|rcsb pdb:4EH4|rcsb pdb:4EH5|rcsb pdb:4EH6|rcsb pdb:4EH7|rcsb pdb:4EH8|rcsb pdb:4EH9|rcsb pdb:4EHV|rcsb pdb:4EWQ|rcsb pdb:4F9W|rcsb pdb:4F9Y|rcsb pdb:4FA2|rcsb pdb:4GEO|rcsb pdb:4KIN|rcsb pdb:4KIP|rcsb pdb:4KIQ|rcsb pdb:4L8M|rcsb pdb:4R3C|rcsb pdb:4ZTH|rcsb pdb:5ETA|rcsb pdb:5ETC|rcsb pdb:5ETF|rcsb pdb:5ETI|rcsb pdb:5ML5|rcsb pdb:5MTX|rcsb pdb:5MTY|rcsb pdb:5MZ3|rcsb pdb:5N63|rcsb pdb:5N64|rcsb pdb:5N65|rcsb pdb:5N66|rcsb pdb:5N67|rcsb pdb:5N68|rcsb pdb:5O8U|rcsb pdb:5O8V|rcsb pdb:5OMG|rcsb pdb:5OMH|rcsb pdb:5TBE|rcsb pdb:5TCO|rcsb pdb:5WJJ|rcsb pdb:5XYX|rcsb pdb:5XYY|rcsb pdb:6ANL|rcsb pdb:6HWT|rcsb pdb:6HWU|rcsb pdb:6HWV|rcsb pdb:6M95|rcsb pdb:6M9L|rcsb pdb:6OHD|rcsb pdb:6QDZ|rcsb pdb:6QE1|rcsb pdb:6QYX|rcsb pdb:6RFO|rcsb pdb:6SFI|rcsb pdb:6SFJ|rcsb pdb:6SFK|rcsb pdb:6SFO|rcsb pdb:6TCA|rcsb pdb:6ZQS|rcsb pdb:6ZWP|rcsb pdb:8A8M|rcsb pdb:8VXE|reactome:R-HSA-168638|reactome:R-HSA-171007|reactome:R-HSA-198753|reactome:R-HSA-2151209|reactome:R-HSA-2559580|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-4420097|reactome:R-HSA-450302|reactome:R-HSA-450341|reactome:R-HSA-450604|reactome:R-HSA-525793|reactome:R-HSA-5668599|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-9662834|reactome:R-HSA-9824585|ensembl:ENSP00000229794.4|ensembl:ENST00000229795.8|ensembl:ENSP00000229795.3|ensembl:ENST00000310795.8|ensembl:ENSP00000308669.4"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/06	rogid:8Lhp4NihTUjn3nGZLA2K6kHbXg8632	rogid:oI6EOrCDVMQ6FDVBHSiYYoKZHns9606	intact-crc:496E005FD6E23FC3|rigid:sIr9iCIfIfw/818RRF4dLkwHtjM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A7Y8RC16	uniprotkb:Q969V6	intact:EBI-2843188|uniprotkb:Q74PV7|uniprotkb:A0A0H2W7X5|uniprotkb:Q7CG44|uniprotkb:Q0WJQ7|uniprotkb:A0A384KPQ0	intact:EBI-493122|uniprotkb:Q8TCL1|uniprotkb:Q96SC5|uniprotkb:Q96SC6|uniprotkb:Q9P2B0|ensembl:ENSP00000385835.1|intact:EBI-28979024	psi-mi:a0a7y8rc16_yerpe(display_long)|uniprotkb:YPO0404(locus name)	psi-mi:mrtfa_human(display_long)|uniprotkb:MRTFA(gene name)|psi-mi:MRTFA(display_short)|uniprotkb:KIAA1438(gene name synonym)|uniprotkb:MAL(gene name synonym)|uniprotkb:MKL/myocardin-like protein 1(gene name synonym)|uniprotkb:MKL1(gene name synonym)|uniprotkb:Megakaryoblastic leukemia 1 protein(gene name synonym)|uniprotkb:Megakaryocytic acute leukemia protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864353|imex:IM-13779-6971	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR006327(Phosphotransferase system, fructose IIC component)|interpro:IPR013014(Phosphotransferase system, EIIC component, type 2)|go:""GO:0005351""(""carbohydrate:proton symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|refseq:YP_002345481.1|interpro:IPR050864"	"ensembl:ENSG00000196588.21(gene)|ensembl:ENST00000407029.7(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003779""(actin binding)|go:""GO:0003785""(actin monomer binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0043522""(leucine zipper domain binding)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051145""(smooth muscle cell differentiation)|go:""GO:1902895""(positive regulation of miRNA transcription)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004018(RPEL repeat)|interpro:IPR036361|interpro:IPR043451|mint:Q969V6|rcsb pdb:2KVU|rcsb pdb:2KW9|reactome:R-HSA-3899300|reactome:R-HSA-5663220|refseq:NP_001269589.1|refseq:NP_001269590.1|refseq:NP_065882.1|refseq:XP_005261751.1|efo:""Orphanet:402023""|efo:""Orphanet:619941""|panther:PTHR22793(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SLkzxzvdatLCfveYdH0UaKifvHU632	rogid:m9kdYm+MiCAqHa/IUa44qp33h9U9606	intact-crc:18ECE2F1FF5FABD4|rigid:8gsbRdycZZ54SW+NmexHdCKac9I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HBH9	uniprotkb:Q8CZY7	intact:EBI-2864341|uniprotkb:Q6GPI3|uniprotkb:Q9UHR0|uniprotkb:Q9Y2N6|uniprotkb:Q9HBH8|ensembl:ENSP00000250896.3	intact:EBI-2842279|uniprotkb:Q0WI10|uniprotkb:Q8ZH74	psi-mi:mknk2_human(display_long)|uniprotkb:MKNK2(gene name)|psi-mi:MKNK2(display_short)|uniprotkb:GPRK7(gene name synonym)|uniprotkb:MNK2(gene name synonym)|uniprotkb:MAP kinase signal-integrating kinase 2(gene name synonym)	psi-mi:sydp_yerpe(display_long)|uniprotkb:syd(gene name)|psi-mi:syd(display_short)|uniprotkb:YPO1035(locus name)|uniprotkb:y3146(locus name)|uniprotkb:YP_2816(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864338|imex:IM-13779-6973	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060042.2|refseq:NP_951009.1|ensembl:ENSG00000099875.16(gene)|ensembl:ENST00000250896.9(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004683""(calcium/calmodulin-dependent protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009931""(calcium-dependent protein serine/threonine kinase activity)|go:""GO:0016604""(nuclear body)|go:""GO:0016605""(PML body)|go:""GO:0030097""(hemopoiesis)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0071243""(cellular response to arsenic-containing substance)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050205|rcsb pdb:2AC3|rcsb pdb:2AC5|rcsb pdb:2HW7|rcsb pdb:6CJ5|rcsb pdb:6CJE|rcsb pdb:6CJH|rcsb pdb:6CJW|rcsb pdb:6CJY|rcsb pdb:6CK3|rcsb pdb:6CK6|rcsb pdb:6CKI|rcsb pdb:6JLR|rcsb pdb:8P9B|rcsb pdb:8XFM|panther:PTHR24349(orthology-group)"	"interpro:IPR009948(Syd)|interpro:IPR038228|go:""GO:0009898""(cytoplasmic side of plasma membrane)|refseq:WP_002212123.1|refseq:YP_002346078.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YqhSqaXd4WQ//OO3M5wnAf0klb49606	rogid:MC0GRav9hd62E9fkiCF0MQ5eBt4632	intact-crc:6E96642678887740|rigid:+4KI3xYK3cNsNlYPt3Nmp45DWqw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YHQ6	uniprotkb:Q15773	intact:EBI-2864330|uniprotkb:Q74VQ5|uniprotkb:A0A0H2W376|uniprotkb:Q7CHH7|uniprotkb:A0A384KJY0	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630.5|ensembl:ENSP00000403941.1|ensembl:ENSP00000446317.1	psi-mi:a0a5p8yhq6_yerpe(display_long)|uniprotkb:YPO1356(locus name)	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864327|imex:IM-13779-6970	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR021295|refseq:WP_002211363.1|interpro:IPR036291|refseq:YP_002346379.1|panther:PTHR43000(orthology-group)	"refseq:NP_005430.1|ensembl:ENSG00000089693.11(gene)|ensembl:ENST00000203630.10(transcript)|ensembl:ENST00000435120.5(transcript)|ensembl:ENST00000539187.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016020""(membrane)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR019376|mint:Q15773|panther:PTHR13105(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:odiUhCU2SdvAlCgMVLoT5omirwE632	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	intact-crc:7FCE20CDF744652A|rigid:0E2i22R3sIzUcAAouQsAuu7L+Do	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PME5	uniprotkb:Q96T58	intact:EBI-2843109|uniprotkb:Q74XQ1|uniprotkb:A0A0H2W1F9|uniprotkb:Q7CKB7|uniprotkb:A0A384KR24	intact:EBI-765739|uniprotkb:Q9UQ01|uniprotkb:Q9Y556|uniprotkb:Q9H9A8|uniprotkb:Q9NWH5|ensembl:ENSP00000364912.3|intact:EBI-28975565	psi-mi:a0a2s9pme5_yerpe(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:YPO3337(locus name)	psi-mi:mint_human(display_long)|uniprotkb:SPEN homolog(gene name synonym)|uniprotkb:SMART/HDAC1-associated repressor protein(gene name synonym)|uniprotkb:KIAA0929(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:SHARP(gene name synonym)|uniprotkb:SPEN(gene name)|psi-mi:SPEN(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864374|imex:IM-13779-6978	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|go:""GO:0004239""(initiator methionyl aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|refseq:WP_002209416.1|interpro:IPR036005|refseq:YP_002348233.1|panther:PTHR43330(orthology-group)"	"efo:""Orphanet:1606""|ensembl:ENSG00000065526.13(gene)|ensembl:ENST00000375759.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034172|interpro:IPR034173|interpro:IPR034174|interpro:IPR034175|interpro:IPR035979|interpro:IPR049093|interpro:IPR049094|interpro:IPR049095|mint:Q96T58|rcsb pdb:1OW1|rcsb pdb:2RT5|rcsb pdb:4P6Q|rcsb pdb:7Z1K|reactome:R-HSA-9013422|refseq:NP_055816.2|dip:DIP-34569N|efo:""Orphanet:662234""|panther:PTHR23189(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:NidRuZki0mfu471s0HwP6hVVvx4632	rogid:m7bdkKVATaG4dkFG/BYXRn4jOIk9606	intact-crc:DC9B0320B6A0B446|rigid:n9C/WdDpTGIt3htIatPiPVq+0m0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96T58	uniprotkb:P58411	intact:EBI-765739|uniprotkb:Q9UQ01|uniprotkb:Q9Y556|uniprotkb:Q9H9A8|uniprotkb:Q9NWH5|ensembl:ENSP00000364912.3|intact:EBI-28975565	intact:EBI-2842569|uniprotkb:Q0WH51	psi-mi:mint_human(display_long)|uniprotkb:SPEN homolog(gene name synonym)|uniprotkb:SMART/HDAC1-associated repressor protein(gene name synonym)|uniprotkb:KIAA0929(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:SHARP(gene name synonym)|uniprotkb:SPEN(gene name)|psi-mi:SPEN(display_short)	psi-mi:maca_yerpe(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:YPO1364(locus name)|uniprotkb:y2814(locus name)|uniprotkb:YP_1230(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864381|imex:IM-13779-6976	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1606""|ensembl:ENSG00000065526.13(gene)|ensembl:ENST00000375759.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034172|interpro:IPR034173|interpro:IPR034174|interpro:IPR034175|interpro:IPR035979|interpro:IPR049093|interpro:IPR049094|interpro:IPR049095|mint:Q96T58|rcsb pdb:1OW1|rcsb pdb:2RT5|rcsb pdb:4P6Q|rcsb pdb:7Z1K|reactome:R-HSA-9013422|refseq:NP_055816.2|dip:DIP-34569N|efo:""Orphanet:662234""|panther:PTHR23189(orthology-group)"	"interpro:IPR006143(Secretion protein HlyD)|go:""GO:0005886""(plasma membrane)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:0019898""(extrinsic component of membrane)|go:""GO:0046677""(response to antibiotic)|go:""GO:1990195""(macrolide transmembrane transporter complex)|go:""GO:1990281""(efflux pump complex)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR030190|interpro:IPR032317|refseq:YP_002346387.1|panther:PTHR30469(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:m7bdkKVATaG4dkFG/BYXRn4jOIk9606	rogid:rKYMXybMzwlcyfy9qX59sfo1BVM632	intact-crc:FE6D42091A72B24B|rigid:+T84pi741rBQOHnFmuT+TrEkHRI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N3F8	uniprotkb:A0A3G5LBG9	intact:EBI-1056885|uniprotkb:Q5TI16|uniprotkb:Q7RTP5|uniprotkb:Q8N3N8|uniprotkb:Q9BVL9|uniprotkb:Q9BY92|uniprotkb:Q9UH43|uniprotkb:Q9UH44|uniprotkb:Q9UH45|ensembl:ENSP00000215957.6	intact:EBI-2843337|uniprotkb:Q7ARE7|uniprotkb:Q7BT22|uniprotkb:A0A1U8QL38|uniprotkb:O68742|uniprotkb:Q65AP5|uniprotkb:A0A2S9PDV0	psi-mi:milk1_human(display_long)|uniprotkb:MICALL1(gene name)|psi-mi:MICALL1(display_short)|uniprotkb:KIAA1668(gene name synonym)|uniprotkb:MIRAB13(gene name synonym)|uniprotkb:Molecule interacting with Rab13(gene name synonym)	psi-mi:a0a3g5lbg9_yerpe(display_long)|uniprotkb:YPMT1.25c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864388|imex:IM-13779-6977	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_203744.1|ensembl:ENSG00000100139.14(gene)|ensembl:ENST00000215957.10(transcript)|go:""GO:0005770""(late endosome)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0010009""(cytoplasmic side of endosome membrane)|go:""GO:0015031""(protein transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032458""(slow endocytic recycling)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070300""(phosphatidic acid binding)|go:""GO:0097320""(plasma membrane tubulation)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR022735|interpro:IPR036872|interpro:IPR050540|mint:Q8N3F8|rcsb pdb:2KSP"	refseq:NP_395361.1|refseq:YP_093902.1|refseq:NP_857661.1|refseq:WP_002211788.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:G64P9EtjEfLIVLYkb+w3vCWaT0w9606	rogid:b42FykicLMYhKQ/f+NviSJexojE632	intact-crc:975D6DD70496E9AC|rigid:730/dsvFPh/l/A1DE6pTM2CCBKU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GWQ4	uniprotkb:Q13164	intact:EBI-2845580|uniprotkb:Q74SR7|uniprotkb:Q0WDH9|uniprotkb:Q7CJQ8|uniprotkb:A0A380PMW3|uniprotkb:A0A384L966	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|ensembl:ENSP00000311005.5|ensembl:ENSP00000378966.4|ensembl:ENSP00000378968.3|intact:EBI-28979986	psi-mi:a0a2u2gwq4_yerpe(display_long)|uniprotkb:mclA(gene name)|psi-mi:mclA(display_short)|uniprotkb:Regulator of SigE(gene name synonym)|uniprotkb:Sigma-E anti-sigma factor RseA(gene name synonym)|uniprotkb:Sigma-E factor negative regulatory protein(gene name synonym)|uniprotkb:rseA(gene name synonym)|uniprotkb:YPO2712(locus name)	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864367|imex:IM-13779-6975	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026279|interpro:IPR005573(Anti sigma-E protein RseA, C-terminal)|interpro:IPR005572(Anti sigma-E protein RseA, N-terminal)|go:""GO:0005886""(plasma membrane)|go:""GO:0016989""(sigma factor antagonist activity)|refseq:WP_002209673.1|interpro:IPR036147|refseq:YP_002347659.1|interpro:IPR052383"	"refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|refseq:XP_011522259.1|ensembl:ENSG00000166484.20(gene)|ensembl:ENST00000308406.9(transcript)|ensembl:ENST00000395602.8(transcript)|ensembl:ENST00000395604.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004705""(JUN kinase activity)|go:""GO:0004707""(MAP kinase activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0016605""(PML body)|go:""GO:0030154""(cell differentiation)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0034115""(negative regulation of heterotypic cell-cell adhesion)|go:""GO:0034392""(negative regulation of smooth muscle cell apoptotic process)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0071499""(cellular response to laminar fluid shear stress)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050117|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|rcsb pdb:7PUS|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|panther:PTHR24055(orthology-group)|ensembl:ENST00000299612.11|ensembl:ENSP00000299612.7|ensembl:ENSP00000311005.5|ensembl:ENSP00000378966.4|ensembl:ENSP00000378968.3"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LwZJGFoSTyhBT8PD/0j5gaZwEWc632	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	intact-crc:0BDC714B3FCFB1F7|rigid:JrRxWAjc8YHR4sTLIyNXBKV35UE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96AX9	uniprotkb:Q8D1R1	intact:EBI-2130249|ensembl:ENSP00000348081.6|ensembl:ENSP00000426103.3|ensembl:ENSP00000426128.2|uniprotkb:B4DZ57|uniprotkb:J3KNZ7|uniprotkb:A2AGM5|uniprotkb:A2AGM6|uniprotkb:B3KV93|uniprotkb:B3KVF4|uniprotkb:Q7Z437|uniprotkb:Q8IY62|uniprotkb:Q8N786|uniprotkb:Q8N897|uniprotkb:Q8N8R2|uniprotkb:Q8N911|uniprotkb:Q8NB36|uniprotkb:Q8NCY1|uniprotkb:Q8NG59|uniprotkb:Q8NG60|uniprotkb:Q8NG61|uniprotkb:Q8NI59|uniprotkb:Q8WYN1|intact:EBI-11116994|uniprotkb:B3KXY1|uniprotkb:E9PGU1|uniprotkb:E9PHQ1|uniprotkb:F8WA73|intact:EBI-28979050	intact:EBI-2864398|uniprotkb:Q74PR9	psi-mi:mib2_human(display_long)|uniprotkb:MIB2(gene name)|psi-mi:MIB2(display_short)|uniprotkb:SKD(gene name synonym)|uniprotkb:ZZANK1(gene name synonym)|uniprotkb:Mind bomb homolog 2(gene name synonym)|uniprotkb:Zinc finger ZZ type with ankyrin repeat domain protein 1(gene name synonym)|uniprotkb:Skeletrophin(gene name synonym)|uniprotkb:Novel zinc finger protein(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 002N(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIB2(gene name synonym)	psi-mi:q8d1r1_yerpe(display_long)|uniprotkb:YP_3819(locus name)|uniprotkb:zapE(gene name)|psi-mi:zapE(display_short)|uniprotkb:Z ring-associated protein ZapE(gene name synonym)|uniprotkb:y0135(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864395|imex:IM-13779-6979	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000197530.13(gene)|ensembl:ENST00000355826.10(transcript)|ensembl:ENST00000504599.6(transcript)|ensembl:ENST00000505820.7(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0003779""(actin binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR010606(Mib-herc2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036770|interpro:IPR037252|interpro:IPR040847|interpro:IPR042056|interpro:IPR043145|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-9013507|reactome:R-HSA-983168|refseq:NP_001164157.1|refseq:NP_001164158.1|refseq:NP_001164159.1|refseq:NP_001164160.1|refseq:NP_543151.2|refseq:XP_011539043.1|efo:""Orphanet:54260""|panther:PTHR24202(orthology-group)"	"interpro:IPR005654(AFG1-like ATPase)|interpro:IPR027417|interpro:IPR030870|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0051301""(cell division)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EtV2fvBb1DquIsRUSCkR1A62ULc9606	rogid:nuM9EfDaO8PH0r3zv3qNyWs/lP0632	intact-crc:F0C50A98D5F198C6|rigid:wqvdvC2lrAweo/TmTv2996DUpJA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q09328	uniprotkb:A0A2S9PID6	intact:EBI-2864413|uniprotkb:D3DP70|ensembl:ENSP00000281923.2|ensembl:ENSP00000386377.1	intact:EBI-2852541|uniprotkb:Q7CJ99|uniprotkb:Q0WDA9	psi-mi:mgt5a_human(display_long)|uniprotkb:MGAT5(gene name)|psi-mi:MGAT5(display_short)|uniprotkb:GGNT5(gene name synonym)|uniprotkb:GlcNAc-T V(gene name synonym)|uniprotkb:Mannoside acetylglucosaminyltransferase 5(gene name synonym)|uniprotkb:N-acetylglucosaminyl-transferase V(gene name synonym)|uniprotkb:Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V(gene name synonym)	psi-mi:a0a2s9pid6_yerpe(display_long)|uniprotkb:Ascorbate-specific permease IIC component UlaA(gene name synonym)|uniprotkb:YPO2782(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864417|imex:IM-13779-6981	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011509501.1|refseq:XP_011509502.1|refseq:XP_011509503.1|refseq:XP_011509504.1|refseq:XP_006712597.1|refseq:NP_002401.1|refseq:XP_016859636.1|refseq:XP_016859637.1|refseq:XP_005263725.1|refseq:XP_005263726.1|refseq:XP_005263727.1|ensembl:ENSG00000152127.9(gene)|ensembl:ENST00000281923.4(transcript)|ensembl:ENST00000409645.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0016020""(membrane)|go:""GO:0018279""(protein N-linked glycosylation via asparagine)|go:""GO:0019082""(viral protein processing)|go:""GO:0030144""(alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904894""(positive regulation of receptor signaling pathway via STAT)|interpro:IPR026116|interpro:IPR027833|interpro:IPR052105|rcsb pdb:5ZIB|rcsb pdb:5ZIC|rcsb pdb:6YJQ|rcsb pdb:6YJR|rcsb pdb:6YJS|rcsb pdb:6YJT|rcsb pdb:6YJU|rcsb pdb:6YJV|rcsb pdb:7YYI|rcsb pdb:7Z07|rcsb pdb:7Z08|rcsb pdb:7Z0B|rcsb pdb:8CE3|rcsb pdb:9F5H|reactome:R-HSA-9694548|reactome:R-HSA-975577|panther:PTHR15075(orthology-group)"	"interpro:IPR051562|interpro:IPR004703(Phosphotransferase system, galactitol-specific IIC component)|refseq:WP_002222248.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|refseq:YP_002347729.1|panther:PTHR33843(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XPhy8p3/7Dwm1O2O9GBjKNc+p509606	rogid:HGM5YqpTTcqbe/pNI0T33Mxne/w632	intact-crc:C39C94612DA31E38|rigid:EOtaDZ7hpj8gcoUJFBQbIhpusyQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ16	uniprotkb:O43451	intact:EBI-2841852|uniprotkb:Q0WJZ3	intact:EBI-2829774|uniprotkb:Q86UM5|uniprotkb:Q75ME7|uniprotkb:Q0VAX6|ensembl:ENSP00000417515.2|uniprotkb:E7ER45	psi-mi:lexa_yerpe(display_long)|uniprotkb:lexA(gene name)|psi-mi:lexA(display_short)|uniprotkb:YPO0314(locus name)|uniprotkb:y0572(locus name)|uniprotkb:YP_0470(locus name)	psi-mi:mga_human(display_long)|uniprotkb:MGAM(gene name)|psi-mi:MGAM(display_short)|uniprotkb:MGA(gene name synonym)|uniprotkb:MGAML(gene name synonym)|uniprotkb:Alpha-1,4-glucosidase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864431|imex:IM-13779-6980	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039418|interpro:IPR006199(LexA DNA-binding region)|interpro:IPR006200(Peptidase S24, LexA repressor)|interpro:IPR006197(Peptidase S24, LexA/MucA/RumA/RuvA)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0009432""(SOS response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002345395.1|refseq:WP_002209090.1|interpro:IPR036286|interpro:IPR036388|interpro:IPR036390|interpro:IPR050077|panther:PTHR33516(orthology-group)"	"refseq:NP_004659.2|ensembl:ENSG00000257335.8(gene)|ensembl:ENST00000475668.6(transcript)|go:""GO:0000025""(maltose catabolic process)|go:""GO:0003824""(catalytic activity)|go:""GO:0004339""(glucan 1,4-alpha-glucosidase activity)|go:""GO:0004558""(alpha-1,4-glucosidase activity)|go:""GO:0004574""(oligo-1,6-glucosidase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005983""(starch catabolic process)|go:""GO:0016160""(amylase activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901027""(dextrin catabolic process)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR000519(P-type trefoil)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017957|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|interpro:IPR044913|interpro:IPR048395|mint:O43451|rcsb pdb:2QLY|rcsb pdb:2QMJ|rcsb pdb:3CTT|rcsb pdb:3L4T|rcsb pdb:3L4U|rcsb pdb:3L4V|rcsb pdb:3L4W|rcsb pdb:3L4X|rcsb pdb:3L4Y|rcsb pdb:3L4Z|rcsb pdb:3TON|rcsb pdb:3TOP|reactome:R-HSA-189085|reactome:R-HSA-6798695|refseq:XP_011514974.1|refseq:XP_011514975.1|refseq:XP_016868261.1|refseq:XP_011514973.1|refseq:XP_006716231.1|refseq:XP_011514972.1|panther:PTHR22762(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1RBPmARbsfVEavq4/r0MVDBH/Og632	rogid:YHyyyj0ELDf6xmuOts5HJUEpkR89606	intact-crc:69C9E0EBD80D563A|rigid:Yyh1XAyDAexroHhvl8+OOAqWjkg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZU2	uniprotkb:Q96AX9	intact:EBI-2843382	intact:EBI-2130249|ensembl:ENSP00000348081.6|ensembl:ENSP00000426103.3|ensembl:ENSP00000426128.2|uniprotkb:B4DZ57|uniprotkb:J3KNZ7|uniprotkb:A2AGM5|uniprotkb:A2AGM6|uniprotkb:B3KV93|uniprotkb:B3KVF4|uniprotkb:Q7Z437|uniprotkb:Q8IY62|uniprotkb:Q8N786|uniprotkb:Q8N897|uniprotkb:Q8N8R2|uniprotkb:Q8N911|uniprotkb:Q8NB36|uniprotkb:Q8NCY1|uniprotkb:Q8NG59|uniprotkb:Q8NG60|uniprotkb:Q8NG61|uniprotkb:Q8NI59|uniprotkb:Q8WYN1|intact:EBI-11116994|uniprotkb:B3KXY1|uniprotkb:E9PGU1|uniprotkb:E9PHQ1|uniprotkb:F8WA73|intact:EBI-28979050	psi-mi:q8czu2_yerpe(display_long)|uniprotkb:yapH(gene name)|psi-mi:yapH(display_short)|uniprotkb:y3396(locus name)	psi-mi:mib2_human(display_long)|uniprotkb:MIB2(gene name)|psi-mi:MIB2(display_short)|uniprotkb:SKD(gene name synonym)|uniprotkb:ZZANK1(gene name synonym)|uniprotkb:Mind bomb homolog 2(gene name synonym)|uniprotkb:Zinc finger ZZ type with ankyrin repeat domain protein 1(gene name synonym)|uniprotkb:Skeletrophin(gene name synonym)|uniprotkb:Novel zinc finger protein(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 002N(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIB2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864406|imex:IM-13779-6984	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR024973|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0019867""(outer membrane)|interpro:IPR036709|interpro:IPR043990|interpro:IPR050909"	"ensembl:ENSG00000197530.13(gene)|ensembl:ENST00000355826.10(transcript)|ensembl:ENST00000504599.6(transcript)|ensembl:ENST00000505820.7(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0003779""(actin binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR010606(Mib-herc2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036770|interpro:IPR037252|interpro:IPR040847|interpro:IPR042056|interpro:IPR043145|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-9013507|reactome:R-HSA-983168|refseq:NP_001164157.1|refseq:NP_001164158.1|refseq:NP_001164159.1|refseq:NP_001164160.1|refseq:NP_543151.2|refseq:XP_011539043.1|efo:""Orphanet:54260""|panther:PTHR24202(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:w2l6qUtIv4INNGQ9HeM84bFptXU632	rogid:EtV2fvBb1DquIsRUSCkR1A62ULc9606	intact-crc:977043CFD5151A8D|rigid:Qw4mKNky10kPUY98MXoqjd7w+oI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y4C4	uniprotkb:P68587	intact:EBI-2864441|uniprotkb:Q96CI0|ensembl:ENSP00000276282.6	intact:EBI-2844901|uniprotkb:P40295	psi-mi:mfha1_human(display_long)|uniprotkb:MFHAS1(gene name)|psi-mi:MFHAS1(display_short)|uniprotkb:MASL1(gene name synonym)|uniprotkb:Malignant fibrous histiocytoma-amplified sequence with leucine-rich tandem repeats 1(gene name synonym)	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864438|imex:IM-13779-6982	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004216.2|ensembl:ENSG00000147324.11(gene)|ensembl:ENST00000276282.7(transcript)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006954""(inflammatory response)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034121""(regulation of toll-like receptor signaling pathway)|go:""GO:0034136""(negative regulation of toll-like receptor 2 signaling pathway)|go:""GO:0034137""(positive regulation of toll-like receptor 2 signaling pathway)|go:""GO:0034144""(negative regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0045087""(innate immune response)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1900745""(positive regulation of p38MAPK cascade)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR020859|interpro:IPR027417|interpro:IPR032675|interpro:IPR050216|mint:Q9Y4C4|panther:PTHR45752(orthology-group)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FOUfqBu2VnCrvdDh6S0Rz4Mq6Hw9606	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	intact-crc:070DC3EAAC334835|rigid:8irGsuqpgVYaXQ63NLykiqF9WOU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UQ53	uniprotkb:A0A0H2W8Z8	intact:EBI-725713|uniprotkb:Q86TF1|uniprotkb:Q96GH4|uniprotkb:Q9NSK6|uniprotkb:A8MPR0|ensembl:ENSP00000292591.7|ensembl:ENSP00000492708.1	intact:EBI-2856746|uniprotkb:Q74QD6|uniprotkb:A0A3N4B8Z3|uniprotkb:Q7CGV9|uniprotkb:Q0WII5	"psi-mi:mgt4b_human(display_long)|uniprotkb:""UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb""(gene name synonym)|uniprotkb:N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb(gene name synonym)|uniprotkb:MGAT4B(gene name)|psi-mi:MGAT4B(display_short)|uniprotkb:UNQ906/PRO1927(orf name)"	psi-mi:a0a0h2w8z8_yerpe(display_long)|uniprotkb:bgaB(gene name)|psi-mi:bgaB(display_short)|uniprotkb:pbg(gene name synonym)|uniprotkb:YPO0852(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864424|imex:IM-13779-6983	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055090.1|refseq:NP_463459.1|ensembl:ENSG00000161013.17(gene)|ensembl:ENSG00000284501.2(gene)|ensembl:ENST00000292591.12(transcript)|ensembl:ENST00000638266.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005795""(Golgi stack)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0006491""(N-glycan processing)|go:""GO:0008375""(acetylglucosaminyltransferase activity)|go:""GO:0008454""(alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity)|go:""GO:0019082""(viral protein processing)|go:""GO:0046872""(metal ion binding)|interpro:IPR006759(Glycosyl transferase, family 54)|reactome:R-HSA-9694548|reactome:R-HSA-975577|panther:PTHR12062(orthology-group)"	"interpro:IPR029062|interpro:IPR013739(Beta-galactosidase C-terminal)|interpro:IPR013738(Beta-galactosidase trimerisation)|interpro:IPR003476(Glycoside hydrolase, family 42)|interpro:IPR013529(Glycoside hydrolase, family 42, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209897.1|go:""GO:0004565""(beta-galactosidase activity)|go:""GO:0006012""(galactose metabolic process)|go:""GO:0009341""(beta-galactosidase complex)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:YP_002345903.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DYPkB/KEMLg5SBMW7S9s3rA19xs9606	rogid:FQsKPHA93Zu/VST9+vZv6zeQ8DA632	intact-crc:3E9D319A3077E4AC|rigid:87WPxy3QU4Q15tqzrr/983CG9FA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5U5Q3	uniprotkb:Q8CLC4	intact:EBI-2864451|uniprotkb:Q9NZE3|uniprotkb:A1L022|ensembl:ENSP00000385610.3	intact:EBI-2844860	psi-mi:mex3c_human(display_long)|uniprotkb:MEX3C(gene name)|psi-mi:MEX3C(display_short)|uniprotkb:RKHD2(gene name synonym)|uniprotkb:RNF194(gene name synonym)|uniprotkb:RING finger and KH domain-containing protein 2(gene name synonym)|uniprotkb:RING finger protein 194(gene name synonym)|uniprotkb:BM-013(orf name)|uniprotkb:RING-type E3 ubiquitin transferase MEX3C(gene name synonym)	psi-mi:q8clc4_yerpe(display_long)|uniprotkb:y1644(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864457|imex:IM-13779-6985	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000176624.12(gene)|ensembl:ENST00000406189.4(transcript)|go:""GO:0003415""(chondrocyte hypertrophy)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0045598""(regulation of fat cell differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0097009""(energy homeostasis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036612|interpro:IPR047226|interpro:IPR047227|interpro:IPR047228|mint:Q5U5Q3|rcsb pdb:5WWW|rcsb pdb:5WWX|rcsb pdb:5WWZ|rcsb pdb:5ZI6|reactome:R-HSA-983168|refseq:NP_057710.3|panther:PTHR23285(orthology-group)"	interpro:IPR004375(Conserved hypothetical protein CHP00022)|interpro:IPR037012	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZmQS1ZMrIF33uyR7VW2C4t9cyyk9606	rogid:bRggnpBtWSjyBJTLgvdTftsIYl4632	intact-crc:87813B1C3A4B5706|rigid:1O+vknlGbn0SazadPjHC4mxOykI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31153	uniprotkb:Q8ZAQ2	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|uniprotkb:B4DN45|ensembl:ENSP00000303147.3	intact:EBI-2860892|uniprotkb:Q0WAR9	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:thic_yerpe(display_long)|uniprotkb:thiC(gene name)|psi-mi:thiC(display_short)|uniprotkb:YP_3102(locus name)|uniprotkb:Hydroxymethylpyrimidine phosphate synthase(gene name synonym)|uniprotkb:YPO3739(locus name)|uniprotkb:y0491(locus name)|uniprotkb:Thiamine biosynthesis protein ThiC(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864484|imex:IM-13779-6986	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168906.13(gene)|ensembl:ENST00000306434.8(transcript)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0036094""(small molecule binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048269""(methionine adenosyltransferase complex)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|rcsb pdb:7BHR|rcsb pdb:7BHS|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCF|rcsb pdb:7KCE|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|rcsb pdb:7LNH|rcsb pdb:7RW5|rcsb pdb:7RW7|rcsb pdb:7RWG|rcsb pdb:7RWH|rcsb pdb:7RXV|rcsb pdb:7RXW|rcsb pdb:7RXX|rcsb pdb:8AXZ|rcsb pdb:8OOG|rcsb pdb:8P1T|rcsb pdb:8P1V|rcsb pdb:8P1W|rcsb pdb:8P4H|rcsb pdb:8QDY|rcsb pdb:8QDZ|rcsb pdb:8QE0|rcsb pdb:8QE1|rcsb pdb:8QE2|rcsb pdb:8QE3|rcsb pdb:8XAM|rcsb pdb:8XAR|rcsb pdb:8XB0|reactome:R-HSA-156581|refseq:NP_005902.1|efo:""Orphanet:91387""|panther:PTHR11964(orthology-group)"	"interpro:IPR002817(Thiamine biosynthesis protein ThiC)|refseq:WP_002210682.1|interpro:IPR025747|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0016830""(carbon-carbon lyase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR038521|interpro:IPR037509|refseq:YP_002348619.1|panther:PTHR30557(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	rogid:RVZL9aFEqXV/KORpQabcnqvxVkE632	intact-crc:8E46A25839610A27|rigid:O5asIY9gpgWXIkGsj90WqwBpBm4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31153	uniprotkb:P69984	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|uniprotkb:B4DN45|ensembl:ENSP00000303147.3	intact:EBI-2864464|uniprotkb:Q663J3|uniprotkb:P40299	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:ysct_yerpe(display_long)|uniprotkb:yscT(gene name)|psi-mi:yscT(display_short)|uniprotkb:YPCD1.46(locus name)|uniprotkb:y5032(locus name)|uniprotkb:y0035(locus name)|uniprotkb:YP_pCD37(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864470|imex:IM-13779-6987	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168906.13(gene)|ensembl:ENST00000306434.8(transcript)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0036094""(small molecule binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048269""(methionine adenosyltransferase complex)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|rcsb pdb:7BHR|rcsb pdb:7BHS|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCF|rcsb pdb:7KCE|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|rcsb pdb:7LNH|rcsb pdb:7RW5|rcsb pdb:7RW7|rcsb pdb:7RWG|rcsb pdb:7RWH|rcsb pdb:7RXV|rcsb pdb:7RXW|rcsb pdb:7RXX|rcsb pdb:8AXZ|rcsb pdb:8OOG|rcsb pdb:8P1T|rcsb pdb:8P1V|rcsb pdb:8P1W|rcsb pdb:8P4H|rcsb pdb:8QDY|rcsb pdb:8QDZ|rcsb pdb:8QE0|rcsb pdb:8QE1|rcsb pdb:8QE2|rcsb pdb:8QE3|rcsb pdb:8XAM|rcsb pdb:8XAR|rcsb pdb:8XB0|reactome:R-HSA-156581|refseq:NP_005902.1|efo:""Orphanet:91387""|panther:PTHR11964(orthology-group)"	"interpro:IPR002010(Type III secretion system inner membrane R protein)|interpro:IPR006304(Type III secretion protein SpaR/YscT)|refseq:NP_395180.1|refseq:NP_857736.1|refseq:NP_857931.1|refseq:WP_002212938.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0015031""(protein transport)|panther:PTHR30065(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	rogid:oIqqVosixpdeQowHkjY3R3sHvtQ632	intact-crc:3D35597F4BCF9DEA|rigid:7hmUEqjVrkXsCdM1fdj6cAKnUCM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZEG8	uniprotkb:P31153	intact:EBI-2850725|uniprotkb:Q0WEW2	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|uniprotkb:B4DN45|ensembl:ENSP00000303147.3	psi-mi:trpc_yerpe(display_long)|uniprotkb:YPO2205(locus name)|uniprotkb:y2049(locus name)|uniprotkb:YP_2003(locus name)|uniprotkb:trpC(gene name)|psi-mi:trpC(display_short)	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864477|imex:IM-13779-6988	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR013798(Indole-3-glycerol phosphate synthase)|interpro:IPR001468(Indole-3-glycerol phosphate synthase, central region)|interpro:IPR001240(""N-(5'phosphoribosyl)anthranilate isomerase (PRAI)"")|interpro:IPR011060(Ribulose-phosphate binding barrel)|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004425""(indole-3-glycerol-phosphate synthase activity)|go:""GO:0004640""(phosphoribosylanthranilate isomerase activity)|go:""GO:0006568""(L-tryptophan metabolic process)|refseq:WP_002210632.1|refseq:YP_002347176.1|interpro:IPR045186|panther:PTHR22854(orthology-group)"	"ensembl:ENSG00000168906.13(gene)|ensembl:ENST00000306434.8(transcript)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0036094""(small molecule binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048269""(methionine adenosyltransferase complex)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|rcsb pdb:7BHR|rcsb pdb:7BHS|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCF|rcsb pdb:7KCE|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|rcsb pdb:7LNH|rcsb pdb:7RW5|rcsb pdb:7RW7|rcsb pdb:7RWG|rcsb pdb:7RWH|rcsb pdb:7RXV|rcsb pdb:7RXW|rcsb pdb:7RXX|rcsb pdb:8AXZ|rcsb pdb:8OOG|rcsb pdb:8P1T|rcsb pdb:8P1V|rcsb pdb:8P1W|rcsb pdb:8P4H|rcsb pdb:8QDY|rcsb pdb:8QDZ|rcsb pdb:8QE0|rcsb pdb:8QE1|rcsb pdb:8QE2|rcsb pdb:8QE3|rcsb pdb:8XAM|rcsb pdb:8XAR|rcsb pdb:8XB0|reactome:R-HSA-156581|refseq:NP_005902.1|efo:""Orphanet:91387""|panther:PTHR11964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tXJCmgIVZ8neuY4xm84rcCGGyFA632	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	intact-crc:9F0566583B3B0B99|rigid:zuzLtQZzZhLYhx7fR34MrnQ4NS0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H0X4	uniprotkb:P31153	intact:EBI-2845836|uniprotkb:Q74TA6|uniprotkb:A0A0H2W5M6|uniprotkb:Q7CJ39|uniprotkb:A0A384L4Q0	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|uniprotkb:B4DN45|ensembl:ENSP00000303147.3	psi-mi:a0a2u2h0x4_yerpe(display_long)|uniprotkb:YPO2464(locus name)	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864491|imex:IM-13779-6989	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR013398(CRISPR-associated protein Csy2)|refseq:WP_002211868.1|refseq:YP_002347428.1	"ensembl:ENSG00000168906.13(gene)|ensembl:ENST00000306434.8(transcript)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0036094""(small molecule binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048269""(methionine adenosyltransferase complex)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|rcsb pdb:7BHR|rcsb pdb:7BHS|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCF|rcsb pdb:7KCE|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|rcsb pdb:7LNH|rcsb pdb:7RW5|rcsb pdb:7RW7|rcsb pdb:7RWG|rcsb pdb:7RWH|rcsb pdb:7RXV|rcsb pdb:7RXW|rcsb pdb:7RXX|rcsb pdb:8AXZ|rcsb pdb:8OOG|rcsb pdb:8P1T|rcsb pdb:8P1V|rcsb pdb:8P1W|rcsb pdb:8P4H|rcsb pdb:8QDY|rcsb pdb:8QDZ|rcsb pdb:8QE0|rcsb pdb:8QE1|rcsb pdb:8QE2|rcsb pdb:8QE3|rcsb pdb:8XAM|rcsb pdb:8XAR|rcsb pdb:8XB0|reactome:R-HSA-156581|refseq:NP_005902.1|efo:""Orphanet:91387""|panther:PTHR11964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t5VqVzwIo9m1KhlKCW5QOi7caFo632	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	intact-crc:2E331B0A86294E58|rigid:ymNeybCF9c5MMEFQ6HwQQG1m8fU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O68779	uniprotkb:P31153	intact:EBI-2853455|intact:EBI-2855635|uniprotkb:Q74YF2|uniprotkb:Q7ARB0|uniprotkb:Q7BT13|uniprotkb:A0A3G5L6V4|uniprotkb:A0A1U8QYA4|uniprotkb:A0A0H2W5L4|uniprotkb:Q7CIE2	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|uniprotkb:B4DN45|ensembl:ENSP00000303147.3	psi-mi:o68779_yerpe(display_long)|uniprotkb:y1062(gene name)|psi-mi:y1062(display_short)|uniprotkb:ypmt1.80C(gene name synonym)|uniprotkb:ISU59_11670(orf name)|uniprotkb:ISU59_12615(orf name)|uniprotkb:YPMT1.80c(locus name)|uniprotkb:YPO0011(locus name)|uniprotkb:YPO1493(locus name)|uniprotkb:YPO1561(locus name)|uniprotkb:YPO1583(locus name)|uniprotkb:YPO1589(locus name)|uniprotkb:YPO1621(locus name)|uniprotkb:YPO1727(locus name)|uniprotkb:YPO1988(locus name)|uniprotkb:YPO2104(locus name)|uniprotkb:YPO2136(locus name)|uniprotkb:YPO2170(locus name)|uniprotkb:YPO2194(locus name)|uniprotkb:YPO2447(locus name)|uniprotkb:YPO2571(locus name)|uniprotkb:YPO2656(locus name)|uniprotkb:YPO2783(locus name)|uniprotkb:YPO2799(locus name)|uniprotkb:YPO2862(locus name)|uniprotkb:YPO2942(locus name)|uniprotkb:YPO3875(locus name)	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864505|imex:IM-13779-6990	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395426.1|refseq:NP_857700.1|interpro:IPR001207(Transposase, mutator type)|refseq:YP_093966.1|refseq:WP_002209743.1|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|refseq:YP_002347531.1|refseq:YP_002345107.1|refseq:YP_002346509.1|refseq:YP_002346575.1|refseq:YP_002346595.1|refseq:YP_002346600.1|refseq:YP_002346632.1|refseq:YP_002346729.1|refseq:YP_002346973.1|refseq:YP_002347085.1|refseq:YP_002347114.1|refseq:YP_002347145.1|refseq:YP_002347167.1|refseq:YP_002347411.1|refseq:YP_002347607.1|refseq:YP_002347730.1|refseq:YP_002347741.1|refseq:YP_002347797.1|refseq:YP_002347869.1|refseq:YP_002348751.1|panther:PTHR33217(orthology-group)"	"ensembl:ENSG00000168906.13(gene)|ensembl:ENST00000306434.8(transcript)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0036094""(small molecule binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048269""(methionine adenosyltransferase complex)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|rcsb pdb:7BHR|rcsb pdb:7BHS|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCF|rcsb pdb:7KCE|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|rcsb pdb:7LNH|rcsb pdb:7RW5|rcsb pdb:7RW7|rcsb pdb:7RWG|rcsb pdb:7RWH|rcsb pdb:7RXV|rcsb pdb:7RXW|rcsb pdb:7RXX|rcsb pdb:8AXZ|rcsb pdb:8OOG|rcsb pdb:8P1T|rcsb pdb:8P1V|rcsb pdb:8P1W|rcsb pdb:8P4H|rcsb pdb:8QDY|rcsb pdb:8QDZ|rcsb pdb:8QE0|rcsb pdb:8QE1|rcsb pdb:8QE2|rcsb pdb:8QE3|rcsb pdb:8XAM|rcsb pdb:8XAR|rcsb pdb:8XB0|reactome:R-HSA-156581|refseq:NP_005902.1|efo:""Orphanet:91387""|panther:PTHR11964(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y/++sl3PEsvjk5YqmX2+hc+8JHM632	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	intact-crc:111B77B766CB1697|rigid:MBLid4anOJ/DePqFWIthUsWqqxc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PJH3	uniprotkb:P50221	intact:EBI-2839884|uniprotkb:Q7CIZ2|uniprotkb:Q0WGC0	intact:EBI-2864512|uniprotkb:Q15069|ensembl:ENSP00000321684.4|uniprotkb:A8MWF9|uniprotkb:A8K524	psi-mi:a0a2s9pjh3_yerpe(display_long)|uniprotkb:mgtC(gene name)|psi-mi:mgtC(display_short)|uniprotkb:YPO1660(locus name)	psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864516|imex:IM-13779-6991	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003416(MgtC/SapB transporter)|interpro:IPR048640|interpro:IPR049177|go:""GO:0005886""(plasma membrane)|refseq:YP_002346668.1|panther:PTHR33778(orthology-group)"	"ensembl:ENSG00000005102.14(gene)|ensembl:ENST00000318579.9(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001757""(somite specification)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0061053""(somite development)|go:""GO:0061056""(sclerotome development)|go:""GO:0071837""(HMG box domain binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|mint:P50221|refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|efo:""Orphanet:2345""|panther:PTHR24328(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uPB8dbfu1Sb5/L3fJ2zFWCc7gWs632	rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606	intact-crc:AACD306F71A1F721|rigid:83gKhQe/JFjeY5OBQ6Xn6xfFuiE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31153	uniprotkb:A0A2U2GXH7	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|uniprotkb:B4DN45|ensembl:ENSP00000303147.3	intact:EBI-2848470|uniprotkb:Q74WH6|uniprotkb:Q0WHG3|uniprotkb:A0A0H2W2J4|uniprotkb:Q7CHB5|uniprotkb:A0A384K9G2	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:a0a2u2gxh7_yerpe(display_long)|uniprotkb:YPO1246(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864498|imex:IM-13779-6992	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168906.13(gene)|ensembl:ENST00000306434.8(transcript)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0036094""(small molecule binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048269""(methionine adenosyltransferase complex)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|rcsb pdb:7BHR|rcsb pdb:7BHS|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCF|rcsb pdb:7KCE|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|rcsb pdb:7LNH|rcsb pdb:7RW5|rcsb pdb:7RW7|rcsb pdb:7RWG|rcsb pdb:7RWH|rcsb pdb:7RXV|rcsb pdb:7RXW|rcsb pdb:7RXX|rcsb pdb:8AXZ|rcsb pdb:8OOG|rcsb pdb:8P1T|rcsb pdb:8P1V|rcsb pdb:8P1W|rcsb pdb:8P4H|rcsb pdb:8QDY|rcsb pdb:8QDZ|rcsb pdb:8QE0|rcsb pdb:8QE1|rcsb pdb:8QE2|rcsb pdb:8QE3|rcsb pdb:8XAM|rcsb pdb:8XAR|rcsb pdb:8XB0|reactome:R-HSA-156581|refseq:NP_005902.1|efo:""Orphanet:91387""|panther:PTHR11964(orthology-group)"	interpro:IPR009826(DNA circulation, N-terminal)|refseq:WP_002208852.1|refseq:YP_002346275.1|interpro:IPR052399	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	rogid:Qbi9eC3jfsnnPhDaTUvn+57rY7s632	intact-crc:9C6D737DE1D64679|rigid:UEjqup0WIfqX8IxLXubEbc1xOcY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1Q5	uniprotkb:O00470	intact:EBI-2864526	intact:EBI-1210694|uniprotkb:A8MV50|ensembl:ENSP00000272369.8	psi-mi:q8d1q5_yerpe(display_long)|uniprotkb:y0156(locus name)	psi-mi:meis1_human(display_long)|uniprotkb:MEIS1(gene name)|psi-mi:MEIS1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864523|imex:IM-13779-6993	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR003489(Ribosomal protein S30Ae/sigma 54 modulation protein)|interpro:IPR036567	"refseq:NP_002389.1|ensembl:ENSG00000143995.20(gene)|ensembl:ENST00000272369.14(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001525""(angiogenesis)|go:""GO:0001654""(eye development)|go:""GO:0002089""(lens morphogenesis in camera-type eye)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0007420""(brain development)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009880""(embryonic pattern specification)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0030097""(hemopoiesis)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0045638""(negative regulation of myeloid cell differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0060216""(definitive hemopoiesis)|go:""GO:0061049""(cell growth involved in cardiac muscle cell development)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|interpro:IPR050224|mint:O00470|rcsb pdb:4XRS|rcsb pdb:5EGO|reactome:R-HSA-5617472|panther:PTHR11850(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8VhLfSkP99JLm3DB59X5ZnuYtO4632	rogid:X2N9fFxk9ZD7VQHf1oWkxJAtzsc9606	intact-crc:08106AEC72287979|rigid:c3/obda5pTdW7Ca8Tt4qy9TTQ/w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YGL4	uniprotkb:Q14814	intact:EBI-2842269	intact:EBI-2829828|uniprotkb:Q5T9U5|uniprotkb:Q14815|uniprotkb:Q5T9U6|uniprotkb:D3DVC0|ensembl:ENSP00000271555.5|ensembl:ENSP00000517292.1	psi-mi:a0a5p8ygl4_yerpe(display_long)|uniprotkb:y2085(locus name)|uniprotkb:rnfC(gene name)|psi-mi:rnfC(display_short)|uniprotkb:Rnf electron transport complex subunit C(gene name synonym)	psi-mi:mef2d_human(display_long)|uniprotkb:MEF2D(gene name)|psi-mi:MEF2D(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864547|imex:IM-13779-6997	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010208(Electron transport complex, RnfC)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR017896|interpro:IPR017900|interpro:IPR019554|interpro:IPR026902|interpro:IPR037225|refseq:WP_002223606.1|uniprotkb:Q8D0I9(uniprot-removed-ac)|go:""GO:0005886""(plasma membrane)|go:""GO:0009055""(electron transfer activity)|go:""GO:0022900""(electron transport chain)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)"	"refseq:XP_011507871.1|refseq:NP_005911.1|refseq:NP_001258558.1|refseq:XP_005245226.1|refseq:XP_005245227.1|refseq:XP_006711393.1|refseq:XP_006711395.1|refseq:XP_006711396.1|refseq:XP_006711397.1|refseq:XP_016856803.1|refseq:XP_016856804.1|ensembl:ENSG00000116604.19(gene)|ensembl:ENSG00000291761.1(gene)|ensembl:ENST00000348159.9(transcript)|ensembl:ENST00000708596.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001958""(endochondral ossification)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0007399""(nervous system development)|go:""GO:0007512""(adult heart development)|go:""GO:0007517""(muscle organ development)|go:""GO:0030154""(cell differentiation)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|mint:Q14814|rcsb pdb:7X1N|rcsb pdb:8C84|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-525793|reactome:R-HSA-9031628|reactome:R-HSA-9707616|panther:PTHR11945(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NRqQl9HrLq9sWIRyxpxhQ0JPxQo632	rogid:jedvDf/fMyonSO9j1epfMUuj86Y9606	intact-crc:5E868BD21A4BBA73|rigid:KTetnC7eoAktz/rci3mOXaUAWCY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z7M0	uniprotkb:Q8CKF8	intact:EBI-947617|uniprotkb:O75097|uniprotkb:A8KAY0|ensembl:ENSP00000251268.5	intact:EBI-2844579|uniprotkb:Q74RR5	psi-mi:megf8_human(display_long)|uniprotkb:MEGF8(gene name)|psi-mi:MEGF8(display_short)|uniprotkb:EGFL4(gene name synonym)|uniprotkb:KIAA0817(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 4(gene name synonym)|uniprotkb:C19orf49(gene name synonym)	psi-mi:q8ckf8_yerpe(display_long)|uniprotkb:y3542(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864533|imex:IM-13779-6998	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105429.13(gene)|ensembl:ENST00000251268.11(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0003143""(embryonic heart tube morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0035108""(limb morphogenesis)|go:""GO:0035904""(aorta development)|go:""GO:0042074""(cell migration involved in gastrulation)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0048842""(positive regulation of axon extension involved in axon guidance)|go:""GO:0055113""(epiboly involved in gastrulation with mouth forming second)|go:""GO:0060971""(embryonic heart tube left/right pattern formation)|go:""GO:0060972""(left/right pattern formation)|go:""GO:0060976""(coronary vasculature development)|go:""GO:0061371""(determination of heart left/right asymmetry)|go:""GO:1990403""(embryonic brain development)|go:""GO:0061626""(pharyngeal arch artery morphogenesis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071907""(determination of digestive tract left/right asymmetry)|go:""GO:0097094""(craniofacial suture morphogenesis)|go:""GO:0097155""(fasciculation of sensory neuron axon)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016201(Plexin-like fold)|interpro:IPR018097|interpro:IPR024731|interpro:IPR035914|interpro:IPR049883|mint:Q7Z7M0|refseq:NP_001258867.1|refseq:NP_001401.2|efo:""Orphanet:65759""|panther:PTHR23244(orthology-group)"	interpro:IPR037883	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NaA9e3P2Wh8y5vrZQQPOYHh8ogc9606	rogid:bULfeL7EI8ZLrm+OLqILFkvARMg632	intact-crc:923881359E75396D|rigid:ZEQSXqJLOk+/vy4YlrtfKYyyOpE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z7M0	uniprotkb:A0A2S9PJ11	intact:EBI-947617|uniprotkb:O75097|uniprotkb:A8KAY0|ensembl:ENSP00000251268.5	intact:EBI-2843240|uniprotkb:Q74SW1|uniprotkb:Q7CJT3|uniprotkb:A0A380PL96|uniprotkb:Q0WDP0	psi-mi:megf8_human(display_long)|uniprotkb:MEGF8(gene name)|psi-mi:MEGF8(display_short)|uniprotkb:EGFL4(gene name synonym)|uniprotkb:KIAA0817(gene name synonym)|uniprotkb:Epidermal growth factor-like protein 4(gene name synonym)|uniprotkb:C19orf49(gene name synonym)	psi-mi:a0a2s9pj11_yerpe(display_long)|uniprotkb:proW(gene name)|psi-mi:proW(display_short)|uniprotkb:YPO2646(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864540|imex:IM-13779-6994	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000105429.13(gene)|ensembl:ENST00000251268.11(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0003143""(embryonic heart tube morphogenesis)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0035108""(limb morphogenesis)|go:""GO:0035904""(aorta development)|go:""GO:0042074""(cell migration involved in gastrulation)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0048842""(positive regulation of axon extension involved in axon guidance)|go:""GO:0055113""(epiboly involved in gastrulation with mouth forming second)|go:""GO:0060971""(embryonic heart tube left/right pattern formation)|go:""GO:0060972""(left/right pattern formation)|go:""GO:0060976""(coronary vasculature development)|go:""GO:0061371""(determination of heart left/right asymmetry)|go:""GO:1990403""(embryonic brain development)|go:""GO:0061626""(pharyngeal arch artery morphogenesis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071907""(determination of digestive tract left/right asymmetry)|go:""GO:0097094""(craniofacial suture morphogenesis)|go:""GO:0097155""(fasciculation of sensory neuron axon)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016201(Plexin-like fold)|interpro:IPR018097|interpro:IPR024731|interpro:IPR035914|interpro:IPR049883|mint:Q7Z7M0|refseq:NP_001258867.1|refseq:NP_001401.2|efo:""Orphanet:65759""|panther:PTHR23244(orthology-group)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|refseq:WP_002212209.1|interpro:IPR035906|refseq:YP_002347598.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NaA9e3P2Wh8y5vrZQQPOYHh8ogc9606	rogid:BBwCIsPUr1k5paTb1ggfStKFewc632	intact-crc:C0829323BD0BC8F4|rigid:uQQ13SDRq8u48w2WP+N5jYYfj3M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75448	uniprotkb:Q8ZI61	intact:EBI-394523|uniprotkb:Q14143|uniprotkb:Q9NNY5|uniprotkb:A8K4S5|uniprotkb:B3KMR9|ensembl:ENSP00000377686.2	intact:EBI-2856600|uniprotkb:Q0WJ17|uniprotkb:Q8CZR9|uniprotkb:Q74RQ4	psi-mi:med24_human(display_long)|uniprotkb:TRAP100(gene name synonym)|uniprotkb:MED24(gene name)|psi-mi:MED24(display_short)|uniprotkb:DRIP100(gene name synonym)|uniprotkb:KIAA0130(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 100 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 100 kDa component(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 4(gene name synonym)|uniprotkb:ARC100(gene name synonym)|uniprotkb:CRSP4(gene name synonym)|uniprotkb:THRAP4(gene name synonym)	"psi-mi:glne_yerpe(display_long)|uniprotkb:glnE(gene name)|psi-mi:glnE(display_short)|uniprotkb:""ATP:glutamine synthetase adenylyltransferase""(gene name synonym)|uniprotkb:ATase(gene name synonym)|uniprotkb:YPO0653(locus name)|uniprotkb:YP_2968(locus name)|uniprotkb:y3525(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864561|imex:IM-13779-6996	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR12898(orthology-group)|refseq:NP_001072986.1|refseq:NP_055630.2|refseq:NP_001254726.1|ensembl:ENSG00000008838.21(gene)|ensembl:ENST00000394128.7(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016592""(mediator complex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070847""(core mediator complex)|interpro:IPR021429|mint:O75448|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|refseq:XP_016880955.1|dip:DIP-31462N"	"interpro:IPR023057|interpro:IPR005190(Glutamate-ammonia ligase adenylyltransferase)|interpro:IPR013546(GlnD PII-uridylyltransferase)|refseq:WP_002212194.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000820""(regulation of glutamine family amino acid metabolic process)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008882""([glutamate-ammonia-ligase] adenylyltransferase activity)|go:""GO:0047388""([glutamine synthetase]-adenylyl-L-tyrosine phosphorylase activity)|interpro:IPR043519|refseq:YP_002345721.1|panther:PTHR30621(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:H0iGOXcj8Qe1FOU7pOXkhaAS+pc9606	rogid:RoEcJZfF/CSIgmtP9TYrZ6mEC70632	intact-crc:52F34D14E1772DB1|rigid:syI3XBd9Ud4dOY5G85DrlwN4l5o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WBV4	uniprotkb:Q9H204	intact:EBI-2842109|uniprotkb:Q74XQ3|uniprotkb:A0A0H2W0H0|uniprotkb:Q7CKB8|uniprotkb:A0A2U2H0V3|uniprotkb:A0A384KYC4	intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380.6	psi-mi:q0wbv4_yerpe(display_long)|uniprotkb:YPO3339(locus name)	psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864554|imex:IM-13779-6995	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR012927(ShET2 enterotoxin, N-terminal)|refseq:WP_002209414.1|refseq:YP_002348234.1	"refseq:NP_079481.2|panther:PTHR13512(orthology-group)|ensembl:ENSG00000118579.13(gene)|ensembl:ENST00000237380.12(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016020""(membrane)|go:""GO:0016592""(mediator complex)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0051151""(negative regulation of smooth muscle cell differentiation)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070847""(core mediator complex)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hOXvgkRqMIXiGKjghkpCeLIQWYQ632	rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606	intact-crc:3E0371E11EE68513|rigid:p9tl628tv41m3Eu/Gk7xUKFhqiw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q93074	uniprotkb:Q8D1C5	intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193.3	intact:EBI-2842614	psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym)	psi-mi:q8d1c5_yerpe(display_long)|uniprotkb:phnI(gene name)|psi-mi:phnI(display_short)|uniprotkb:y0727(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864594|imex:IM-13779-7001	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000184634.17(gene)|ensembl:ENST00000374080.8(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0014044""(Schwann cell development)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0021510""(spinal cord development)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048702""(embryonic neurocranium morphogenesis)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0090245""(axis elongation involved in somitogenesis)|go:""GO:1990403""(embryonic brain development)|go:""GO:1990508""(CKM complex)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|interpro:IPR051647|mint:Q93074|rcsb pdb:8TQ2|rcsb pdb:8TQC|rcsb pdb:8TQW|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|refseq:NP_005111.2|efo:""Orphanet:2728""|efo:""Orphanet:293707""|efo:""Orphanet:776""|efo:""Orphanet:777""|efo:""Orphanet:93932""|efo:""Orphanet:1415""|dip:DIP-31459N|panther:PTHR46007(orthology-group)"	"interpro:IPR008773(Phosphonate metabolism)|go:""GO:0019634""(organic phosphonate metabolic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606	rogid:AbNsdhrfAkwhBQT3IgXGyOmugPY632	intact-crc:45EAB5BCC7BB2822|rigid:60EeRGSP6JKNtQTSjHonk1NAlQM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60244	uniprotkb:Q8ZAB3	intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720.1	intact:EBI-2843827|uniprotkb:Q0WAB5	psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym)	psi-mi:ilvd_yerpe(display_long)|uniprotkb:ilvD(gene name)|psi-mi:ilvD(display_short)|uniprotkb:YPO3897(locus name)|uniprotkb:y0338(locus name)|uniprotkb:YP_3150(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864580|imex:IM-13779-7002	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004220.2|ensembl:ENSG00000180182.11(gene)|ensembl:ENST00000324817.6(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016592""(mediator complex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070847""(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|interpro:IPR055107|interpro:IPR055113|interpro:IPR055114|interpro:IPR055122|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|dip:DIP-31460N|panther:PTHR12809(orthology-group)"	"interpro:IPR004404(Dihydroxy-acid dehydratase)|interpro:IPR000581(Dihydroxy-acid and 6-phosphogluconate dehydratase)|interpro:IPR020558|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004160""(dihydroxy-acid dehydratase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0016836""(hydro-lyase activity)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|refseq:WP_002212014.1|interpro:IPR037237|interpro:IPR042096|refseq:YP_002348773.1|panther:PTHR43661(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606	rogid:WzBeSkTt0zJwVJ9+DopV7Z9iYeM632	intact-crc:A3A802AD72D9FB75|rigid:2aIblBAtksKgdLkmw4S/KF0oLEU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZGC4	uniprotkb:Q13503	intact:EBI-2864568|uniprotkb:Q0WH36	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892.3	"psi-mi:sys_yerpe(display_long)|uniprotkb:serS(gene name)|psi-mi:serS(display_short)|uniprotkb:""Seryl-tRNA(Ser/Sec) synthetase""(gene name synonym)|uniprotkb:YPO1379(locus name)|uniprotkb:y2796(locus name)|uniprotkb:YP_1214(locus name)|uniprotkb:Seryl-tRNA synthetase(gene name synonym)"	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864573|imex:IM-13779-6999	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR033729|refseq:WP_002211336.1|go:""GO:0004828""(serine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006434""(seryl-tRNA aminoacylation)|go:""GO:0016260""(selenocysteine biosynthetic process)|interpro:IPR042103|refseq:YP_002346402.1|interpro:IPR045864|panther:PTHR43697(orthology-group)"	"panther:PTHR13381(orthology-group)|refseq:NP_004255.2|ensembl:ENSG00000152944.9(gene)|ensembl:ENST00000282892.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070847""(core mediator complex)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110|dip:DIP-31471N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:d6vUh4YErQ9lf7GDHINCSxKQzAU632	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	intact-crc:FE8854DE4C59EEEA|rigid:k1lAZlvhBtELCO04gjwP0u9tJ8I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q93074	uniprotkb:Q7CIZ3	intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193.3	intact:EBI-2852946|uniprotkb:Q74UE1	psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym)	psi-mi:bgal_yerpe(display_long)|uniprotkb:lacZ(gene name)|psi-mi:lacZ(display_short)|uniprotkb:Lactase(gene name synonym)|uniprotkb:YPO1654(locus name)|uniprotkb:y1817(locus name)|uniprotkb:YP_1785(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864601|imex:IM-13779-7003	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000184634.17(gene)|ensembl:ENST00000374080.8(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0014044""(Schwann cell development)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0021510""(spinal cord development)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048702""(embryonic neurocranium morphogenesis)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0090245""(axis elongation involved in somitogenesis)|go:""GO:1990403""(embryonic brain development)|go:""GO:1990508""(CKM complex)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|interpro:IPR051647|mint:Q93074|rcsb pdb:8TQ2|rcsb pdb:8TQC|rcsb pdb:8TQW|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|refseq:NP_005111.2|efo:""Orphanet:2728""|efo:""Orphanet:293707""|efo:""Orphanet:776""|efo:""Orphanet:777""|efo:""Orphanet:93932""|efo:""Orphanet:1415""|dip:DIP-31459N|panther:PTHR46007(orthology-group)"	"interpro:IPR050347|interpro:IPR008979(Galactose-binding like)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR014718(Glycoside hydrolase-type carbohydrate-binding, subgroup)|interpro:IPR006101(Glycoside hydrolase, family 2)|interpro:IPR023232|interpro:IPR023933|interpro:IPR023230|interpro:IPR004199(Glycoside hydrolase, family 42, domain 5)|interpro:IPR006102(Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich)|interpro:IPR006104(Glycoside hydrolase family 2, carbohydrate-binding)|interpro:IPR006103(Glycoside hydrolase family 2, TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002214048.1|interpro:IPR032312|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004565""(beta-galactosidase activity)|go:""GO:0005990""(lactose catabolic process)|go:""GO:0009341""(beta-galactosidase complex)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036156|refseq:YP_002346664.1|panther:PTHR46323(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606	rogid:RFOxfJbd+ZN/lJ/fIfkqbMSwF7w632	intact-crc:2AC1CB1219764FD0|rigid:BK28NfKBNYfjv3zYA3N1pQVoFF4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q93074	uniprotkb:Q8D1M8	intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193.3	intact:EBI-2843956	psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym)	psi-mi:q8d1m8_yerpe(display_long)|uniprotkb:y0257(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864587|imex:IM-13779-7000	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000184634.17(gene)|ensembl:ENST00000374080.8(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0014044""(Schwann cell development)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0021510""(spinal cord development)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048702""(embryonic neurocranium morphogenesis)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0090245""(axis elongation involved in somitogenesis)|go:""GO:1990403""(embryonic brain development)|go:""GO:1990508""(CKM complex)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|interpro:IPR051647|mint:Q93074|rcsb pdb:8TQ2|rcsb pdb:8TQC|rcsb pdb:8TQW|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|refseq:NP_005111.2|efo:""Orphanet:2728""|efo:""Orphanet:293707""|efo:""Orphanet:776""|efo:""Orphanet:777""|efo:""Orphanet:93932""|efo:""Orphanet:1415""|dip:DIP-31459N|panther:PTHR46007(orthology-group)"	interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)|interpro:IPR050708	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606	rogid:CV6eFVldIgYFQRKvjlqv9/IE4do632	intact-crc:CC44B5BCC470FC8D|rigid:XL/ubXjn/ASb3GOSdPSGwnrfWIE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZFX5	uniprotkb:Q9NU22	intact:EBI-2851740|uniprotkb:Q0WGM4	intact:EBI-1050480|uniprotkb:O15019|uniprotkb:Q5T794|ensembl:ENSP00000358400.3	psi-mi:hisx_yerpe(display_long)|uniprotkb:hisD(gene name)|psi-mi:hisD(display_short)|uniprotkb:YPO1548(locus name)|uniprotkb:y2621(locus name)|uniprotkb:YP_1437(locus name)	psi-mi:mdn1_human(display_long)|uniprotkb:MIDAS-containing protein(gene name synonym)|uniprotkb:Dynein-related AAA-ATPase MDN1(gene name synonym)|uniprotkb:MDN1(gene name)|psi-mi:MDN1(display_short)|uniprotkb:KIAA0301(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864636|imex:IM-13779-7007	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR001692(Histidinol dehydrogenase)|interpro:IPR022695|interpro:IPR012131(Histidinol dehydrogenase, prokaryotic)|refseq:WP_002211895.1|go:""GO:0000105""(L-histidine biosynthetic process)|go:""GO:0004399""(histidinol dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0051287""(NAD binding)|refseq:YP_002346564.1|panther:PTHR21256(orthology-group)"	"refseq:NP_055426.1|ensembl:ENSG00000112159.13(gene)|ensembl:ENST00000369393.8(transcript)|go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030687""(preribosome, large subunit precursor)|go:""GO:0045111""(intermediate filament cytoskeleton)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190|interpro:IPR048617|mint:Q9NU22|panther:PTHR48103(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aXT+/ioqFLvYG1ayljhfqLE1ikU632	rogid:/LVYhffZVpP0pYVM6hLNltoc6pY9606	intact-crc:42CCE9B82296F4A6|rigid:ynjDvPjE/KU2xCrSBGtzP5DoVD0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YMT8	uniprotkb:Q9P1T7	intact:EBI-2858655|uniprotkb:A0A1U8QPA8|uniprotkb:O68748|uniprotkb:Q74YN5|uniprotkb:Q7ARE3|uniprotkb:A0A384L3Y0	intact:EBI-2812899|uniprotkb:Q9P1T6|ensembl:ENSP00000377126.1	psi-mi:a0a5p8ymt8_yerpe(display_long)|uniprotkb:YPMT1.30(locus name)	psi-mi:mdfic_human(display_long)|uniprotkb:MDFIC(gene name)|psi-mi:MDFIC(display_short)|uniprotkb:I-mfa domain-containing protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864650|imex:IM-13779-7006	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_395368.1|interpro:IPR027417|interpro:IPR050615|refseq:WP_002211794.1|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|panther:PTHR11274(orthology-group)"	"refseq:NP_001159817.1|refseq:NP_951038.1|ensembl:ENSG00000135272.13(gene)|ensembl:ENST00000393486.6(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030111""(regulation of Wnt signaling pathway)|go:""GO:0030332""(cyclin binding)|go:""GO:0030957""(Tat protein binding)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046328""(regulation of JNK cascade)|go:""GO:0050434""(positive regulation of viral transcription)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR026134|panther:PTHR15304(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BJmupnbfQIWjfKKF1hJ9rDPFilY632	rogid:Ex7BUM4IA7mjwyl6AA4NOvMF5/A9606	intact-crc:D4676A4D2F3F5B81|rigid:71qEJgIkDbNA2P4BnNRlnwCruQg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZGH4	uniprotkb:Q93074	intact:EBI-2864608|uniprotkb:Q0WH90	intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193.3	psi-mi:deoc1_yerpe(display_long)|uniprotkb:deoC1(gene name)|psi-mi:deoC1(display_short)|uniprotkb:2-deoxy-D-ribose 5-phosphate aldolase 1(gene name synonym)|uniprotkb:dra(gene name synonym)|uniprotkb:Phosphodeoxyriboaldolase 1(gene name synonym)|uniprotkb:YPO1323(locus name)|uniprotkb:y2860(locus name)|uniprotkb:YP_1269(locus name)	psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864613|imex:IM-13779-7008	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028581|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011343(Deoxyribose-phosphate aldolase)|interpro:IPR002915(Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase)|refseq:WP_002208769.1|go:""GO:0004139""(deoxyribose-phosphate aldolase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006018""(2-deoxyribose 1-phosphate catabolic process)|go:""GO:0009264""(deoxyribonucleotide catabolic process)|go:""GO:0016052""(carbohydrate catabolic process)|refseq:YP_002346348.1|panther:PTHR10889(orthology-group)"	"ensembl:ENSG00000184634.17(gene)|ensembl:ENST00000374080.8(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0014044""(Schwann cell development)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0021510""(spinal cord development)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048702""(embryonic neurocranium morphogenesis)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0090245""(axis elongation involved in somitogenesis)|go:""GO:1990403""(embryonic brain development)|go:""GO:1990508""(CKM complex)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|interpro:IPR051647|mint:Q93074|rcsb pdb:8TQ2|rcsb pdb:8TQC|rcsb pdb:8TQW|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|refseq:NP_005111.2|efo:""Orphanet:2728""|efo:""Orphanet:293707""|efo:""Orphanet:776""|efo:""Orphanet:777""|efo:""Orphanet:93932""|efo:""Orphanet:1415""|dip:DIP-31459N|panther:PTHR46007(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:xObJogW9LhDlJbxO/HhORI3RLEc632	rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606	intact-crc:D1DC3002C7E5C69D|rigid:kb731WlAqZKCjemC7oOsaFtojsU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PJ11	uniprotkb:Q9P1T7	intact:EBI-2843240|uniprotkb:Q74SW1|uniprotkb:Q7CJT3|uniprotkb:A0A380PL96|uniprotkb:Q0WDP0	intact:EBI-2812899|uniprotkb:Q9P1T6|ensembl:ENSP00000377126.1	psi-mi:a0a2s9pj11_yerpe(display_long)|uniprotkb:proW(gene name)|psi-mi:proW(display_short)|uniprotkb:YPO2646(locus name)	psi-mi:mdfic_human(display_long)|uniprotkb:MDFIC(gene name)|psi-mi:MDFIC(display_short)|uniprotkb:I-mfa domain-containing protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864643|imex:IM-13779-7005	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|refseq:WP_002212209.1|interpro:IPR035906|refseq:YP_002347598.1"	"refseq:NP_001159817.1|refseq:NP_951038.1|ensembl:ENSG00000135272.13(gene)|ensembl:ENST00000393486.6(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030111""(regulation of Wnt signaling pathway)|go:""GO:0030332""(cyclin binding)|go:""GO:0030957""(Tat protein binding)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046328""(regulation of JNK cascade)|go:""GO:0050434""(positive regulation of viral transcription)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR026134|panther:PTHR15304(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BBwCIsPUr1k5paTb1ggfStKFewc632	rogid:Ex7BUM4IA7mjwyl6AA4NOvMF5/A9606	intact-crc:7951783536BF0942|rigid:O3oK9j88mG1fyLsGKz4b6+vupGg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1F5	uniprotkb:P21439	intact:EBI-2855341|uniprotkb:Q74XG8	intact:EBI-2864620|uniprotkb:Q14813|uniprotkb:A4D1D3|uniprotkb:A4D1D4|uniprotkb:A0A2V7|uniprotkb:D6W5P3|uniprotkb:D6W5P4|uniprotkb:A4D1D5|ensembl:ENSP00000265723.4	psi-mi:q8d1f5_yerpe(display_long)|uniprotkb:terD(gene name)|psi-mi:terD(display_short)|uniprotkb:YP_0456(locus name)|uniprotkb:y0559(locus name)	psi-mi:mdr3_human(display_long)|uniprotkb:ABCB4(gene name)|psi-mi:ABCB4(display_short)|uniprotkb:Multidrug resistance protein 3(gene name synonym)|uniprotkb:MDR3(gene name synonym)|uniprotkb:PGY3(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 4(gene name synonym)|uniprotkb:P-glycoprotein 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864629|imex:IM-13779-7004	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051324|interpro:IPR003325(Bacterial stress protein)|go:""GO:0046690""(response to tellurium ion)"	"ensembl:ENSG00000005471.19(gene)|ensembl:ENST00000265723.8(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005548""(phospholipid transporter activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0032376""(positive regulation of cholesterol transport)|go:""GO:0032782""(bile acid secretion)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0045121""(membrane raft)|go:""GO:0045332""(phospholipid translocation)|go:""GO:0046581""(intercellular canaliculus)|go:""GO:0055085""(transmembrane transport)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0061092""(positive regulation of phospholipid translocation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090554""(phosphatidylcholine floppase activity)|go:""GO:0140359""(ABC-type transporter activity)|go:""GO:1901557""(response to fenofibrate)|go:""GO:1903413""(cellular response to bile acid)|go:""GO:2001140""(positive regulation of phospholipid transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|rcsb pdb:6S7P|rcsb pdb:7NIU|rcsb pdb:7NIV|rcsb pdb:7NIW|reactome:R-HSA-1989781|reactome:R-HSA-382556|reactome:R-HSA-5678771|refseq:NP_000434.1|refseq:NP_061337.1|refseq:NP_061338.1|refseq:XP_011514615.1|efo:""Orphanet:69663""|efo:""Orphanet:69665""|efo:""Orphanet:79305""|panther:PTHR24221(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GID0fZFhER54eVQ645Wu5Y80Fxo632	rogid:sD6az1rtunA0lEAYnlvBtY/aTAo9606	intact-crc:52DB93602B3A3266|rigid:qvoJdksdvEa0uOPZqskIM0lcYCg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CIS2	uniprotkb:O60318	intact:EBI-2864684|uniprotkb:Q74TI4	intact:EBI-308480|uniprotkb:Q2M3C1|uniprotkb:Q9UMT4|uniprotkb:C9JL56|uniprotkb:Q6PJP6|uniprotkb:Q9BSY5|ensembl:ENSP00000291688.1|ensembl:ENSP00000380820.1	psi-mi:purr_yerpe(display_long)|uniprotkb:purR(gene name)|psi-mi:purR(display_short)|uniprotkb:Pur regulon repressor(gene name synonym)|uniprotkb:Purine nucleotide synthesis repressor(gene name synonym)|uniprotkb:YPO2387(locus name)|uniprotkb:y1950(locus name)|uniprotkb:YP_2173(locus name)	psi-mi:ganp_human(display_long)|uniprotkb:MCM3AP(gene name)|psi-mi:MCM3AP(display_short)|uniprotkb:GANP(gene name synonym)|uniprotkb:KIAA0572(gene name synonym)|uniprotkb:MAP80(gene name synonym)|uniprotkb:80 kDa MCM3-associated protein(gene name synonym)|uniprotkb:MCM3 acetylating protein(gene name synonym)|uniprotkb:MCM3 acetyltransferase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864681|imex:IM-13779-7011	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000843(Bacterial regulatory protein, LacI)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR023588|interpro:IPR028082|refseq:WP_002210943.1|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002347353.1|interpro:IPR046335|panther:PTHR30146(orthology-group)"	"refseq:NP_003897.2|refseq:XP_005261262.1|refseq:XP_005261260.1|refseq:XP_005261261.1|dip:DIP-31696N|interpro:IPR031907|interpro:IPR031908|interpro:IPR031910|interpro:IPR034265|ensembl:ENSG00000160294.11(gene)|ensembl:ENST00000291688.6(transcript)|ensembl:ENST00000397708.1(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0010484""(histone H3 acetyltransferase activity)|go:""GO:0015031""(protein transport)|go:""GO:0016446""(somatic hypermutation of immunoglobulin genes)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0031965""(nuclear membrane)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0034728""(nucleosome organization)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042393""(histone binding)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0044615""(nuclear pore nuclear basket)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0070390""(transcription export complex 2)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR035979|interpro:IPR045107|mint:O60318|rcsb pdb:4DHX|panther:PTHR12436(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:dzdla2mdqawR0H2DRHviks1p1L0632	rogid:7WgKNrY4EPZGmfDj7es5SWEfTYM9606	intact-crc:E36C34F0F249B64C|rigid:tZDY1t98drbc2YAjgtlS6jIUg4c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15529	uniprotkb:Q8ZIL5	intact:EBI-2623451|uniprotkb:A0T1T0|uniprotkb:A0T1T1|uniprotkb:Q9UCJ4|uniprotkb:Q5VWS7|uniprotkb:Q5HY94|uniprotkb:Q5VWS9|uniprotkb:Q53GV9|uniprotkb:Q9NNW3|uniprotkb:Q15429|uniprotkb:Q9NNW4|uniprotkb:A0T1T2|uniprotkb:Q5VWT1|uniprotkb:Q7Z3R5|uniprotkb:Q9NNW2|uniprotkb:Q6N0A1|uniprotkb:Q5VWS6|uniprotkb:Q5VWS8|uniprotkb:Q5VWT0|uniprotkb:Q5VWT2|ensembl:ENSP00000350893.2	intact:EBI-2855644|uniprotkb:Q0WJI4	psi-mi:mcp_human(display_long)|uniprotkb:MCP(gene name synonym)|uniprotkb:MIC10(gene name synonym)|uniprotkb:TLX(gene name synonym)|uniprotkb:Trophoblast leukocyte common antigen(gene name synonym)|uniprotkb:CD46(gene name)|psi-mi:CD46(display_short)	psi-mi:cara_yerpe(display_long)|uniprotkb:carA(gene name)|psi-mi:carA(display_short)|uniprotkb:Carbamoyl phosphate synthetase glutamine chain(gene name synonym)|uniprotkb:YPO0481(locus name)|uniprotkb:YP_3698(locus name)|uniprotkb:y3693(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864667|imex:IM-13779-7012	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000117335.21(gene)|ensembl:ENST00000358170.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0002079""(inner acrosomal membrane)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007338""(single fertilization)|go:""GO:0008593""(regulation of Notch signaling pathway)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0035581""(sequestering of extracellular ligand from receptor)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0045087""(innate immune response)|go:""GO:0045296""(cadherin binding)|go:""GO:0045591""(positive regulation of regulatory T cell differentiation)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071636""(positive regulation of transforming growth factor beta production)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR017341(Membrane cofactor protein, CD46)|interpro:IPR035976|interpro:IPR051277|mint:P15529|rcsb pdb:1CKL|rcsb pdb:2O39|rcsb pdb:3INB|rcsb pdb:3L89|rcsb pdb:3O8E|rcsb pdb:5FO8|rcsb pdb:8QK3|reactome:R-HSA-977606|refseq:NP_002380.3|refseq:NP_722548.1|refseq:NP_758860.1|refseq:NP_758861.1|refseq:NP_758862.1|refseq:NP_758863.1|refseq:NP_758869.1|refseq:NP_758871.1|refseq:XP_011507865.1|refseq:XP_011507866.1|refseq:XP_016856797.1|refseq:XP_016856798.1|refseq:XP_016856799.1|dip:DIP-41232N|efo:""Orphanet:244242""|efo:""Orphanet:544472""|panther:PTHR19325(orthology-group)"	"interpro:IPR029062|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR017926|refseq:WP_002224759.1|interpro:IPR035686|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0004359""(glutaminase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005951""(carbamoyl-phosphate synthase complex)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|interpro:IPR050472|interpro:IPR036480|refseq:YP_002345554.1|panther:PTHR11405(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:nhB+pnkhLRsOA01ekJ50pkUu3og9606	rogid:jU7sTbYvJhDasXs9v10lgQwS/IE632	intact-crc:5561874E84CB428E|rigid:f+DeVR2OOR/M/4JuS8THGIgwI20	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1H5	uniprotkb:P15529	intact:EBI-2864660	intact:EBI-2623451|uniprotkb:A0T1T0|uniprotkb:A0T1T1|uniprotkb:Q9UCJ4|uniprotkb:Q5VWS7|uniprotkb:Q5HY94|uniprotkb:Q5VWS9|uniprotkb:Q53GV9|uniprotkb:Q9NNW3|uniprotkb:Q15429|uniprotkb:Q9NNW4|uniprotkb:A0T1T2|uniprotkb:Q5VWT1|uniprotkb:Q7Z3R5|uniprotkb:Q9NNW2|uniprotkb:Q6N0A1|uniprotkb:Q5VWS6|uniprotkb:Q5VWS8|uniprotkb:Q5VWT0|uniprotkb:Q5VWT2|ensembl:ENSP00000350893.2	psi-mi:q8d1h5_yerpe(display_long)|uniprotkb:ttr(gene name)|psi-mi:ttr(display_short)|uniprotkb:NCTC5923_00525(orf name)|uniprotkb:y0474(locus name)	psi-mi:mcp_human(display_long)|uniprotkb:MCP(gene name synonym)|uniprotkb:MIC10(gene name synonym)|uniprotkb:TLX(gene name synonym)|uniprotkb:Trophoblast leukocyte common antigen(gene name synonym)|uniprotkb:CD46(gene name)|psi-mi:CD46(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864657|imex:IM-13779-7009	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR050832|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)"	"ensembl:ENSG00000117335.21(gene)|ensembl:ENST00000358170.6(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0002079""(inner acrosomal membrane)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0007338""(single fertilization)|go:""GO:0008593""(regulation of Notch signaling pathway)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0035581""(sequestering of extracellular ligand from receptor)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0045087""(innate immune response)|go:""GO:0045296""(cadherin binding)|go:""GO:0045591""(positive regulation of regulatory T cell differentiation)|go:""GO:0045959""(negative regulation of complement activation, classical pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071636""(positive regulation of transforming growth factor beta production)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR017341(Membrane cofactor protein, CD46)|interpro:IPR035976|interpro:IPR051277|mint:P15529|rcsb pdb:1CKL|rcsb pdb:2O39|rcsb pdb:3INB|rcsb pdb:3L89|rcsb pdb:3O8E|rcsb pdb:5FO8|rcsb pdb:8QK3|reactome:R-HSA-977606|refseq:NP_002380.3|refseq:NP_722548.1|refseq:NP_758860.1|refseq:NP_758861.1|refseq:NP_758862.1|refseq:NP_758863.1|refseq:NP_758869.1|refseq:NP_758871.1|refseq:XP_011507865.1|refseq:XP_011507866.1|refseq:XP_016856797.1|refseq:XP_016856798.1|refseq:XP_016856799.1|dip:DIP-41232N|efo:""Orphanet:244242""|efo:""Orphanet:544472""|panther:PTHR19325(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:I9PiamV0/KfLq5crQbPb/t3VNuU632	rogid:nhB+pnkhLRsOA01ekJ50pkUu3og9606	intact-crc:FDACACF084CA2162|rigid:mZIQ2Pab+WTw9TZThK9Zt8XsWMI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IX19	uniprotkb:Q8ZBZ9	intact:EBI-2816356|uniprotkb:Q8IX20	intact:EBI-2851065|uniprotkb:Q0WC55	psi-mi:mcem1_human(display_long)|uniprotkb:MCEMP1(gene name)|psi-mi:MCEMP1(display_short)|uniprotkb:C19orf59(gene name synonym)	psi-mi:dpo4_yerpe(display_long)|uniprotkb:dinP(gene name synonym)|uniprotkb:YPO3231(locus name)|uniprotkb:y0959(locus name)|uniprotkb:YP_0702(locus name)|uniprotkb:dinB(gene name)|psi-mi:dinB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864693|imex:IM-13779-7013	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_777578.2|go:""GO:0005886""(plasma membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0070821""(tertiary granule membrane)|interpro:IPR038818|reactome:R-HSA-6798695|panther:PTHR37856(orthology-group)"	"interpro:IPR043502|interpro:IPR017961|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR022880|refseq:WP_002208708.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0009432""(SOS response)|go:""GO:0042276""(error-prone translesion synthesis)|interpro:IPR043128|interpro:IPR036775|interpro:IPR053848|refseq:YP_002348133.1|interpro:IPR050116|panther:PTHR11076(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jkUrd4i0968GzmEaxNrRnNAaRBE9606	rogid:dJC1TxxW9BoCSiFaklVosXbx3KY632	intact-crc:C9576DBC248DD1CA|rigid:dGVyowvlhvhQvHm3z4yjzdde1Xc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60318	uniprotkb:A0A3N4B1K0	intact:EBI-308480|uniprotkb:Q2M3C1|uniprotkb:Q9UMT4|uniprotkb:C9JL56|uniprotkb:Q6PJP6|uniprotkb:Q9BSY5|ensembl:ENSP00000291688.1|ensembl:ENSP00000380820.1	intact:EBI-2847163|uniprotkb:Q74WY2|uniprotkb:Q7CK66|uniprotkb:Q0WC40|uniprotkb:A0A0H2W148	psi-mi:ganp_human(display_long)|uniprotkb:MCM3AP(gene name)|psi-mi:MCM3AP(display_short)|uniprotkb:GANP(gene name synonym)|uniprotkb:KIAA0572(gene name synonym)|uniprotkb:MAP80(gene name synonym)|uniprotkb:80 kDa MCM3-associated protein(gene name synonym)|uniprotkb:MCM3 acetylating protein(gene name synonym)|uniprotkb:MCM3 acetyltransferase(gene name synonym)	psi-mi:a0a3n4b1k0_yerpe(display_long)|uniprotkb:hmwC(gene name)|psi-mi:hmwC(display_short)|uniprotkb:YPO3246(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864674|imex:IM-13779-7010	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003897.2|refseq:XP_005261262.1|refseq:XP_005261260.1|refseq:XP_005261261.1|dip:DIP-31696N|interpro:IPR031907|interpro:IPR031908|interpro:IPR031910|interpro:IPR034265|ensembl:ENSG00000160294.11(gene)|ensembl:ENST00000291688.6(transcript)|ensembl:ENST00000397708.1(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0010484""(histone H3 acetyltransferase activity)|go:""GO:0015031""(protein transport)|go:""GO:0016446""(somatic hypermutation of immunoglobulin genes)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0031965""(nuclear membrane)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0034728""(nucleosome organization)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042393""(histone binding)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0044615""(nuclear pore nuclear basket)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0070390""(transcription export complex 2)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR035979|interpro:IPR045107|mint:O60318|rcsb pdb:4DHX|panther:PTHR12436(orthology-group)"	"interpro:IPR040542|refseq:WP_002208722.1|go:""GO:0016757""(glycosyltransferase activity)|interpro:IPR041109|refseq:YP_002348148.1|interpro:IPR051939"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7WgKNrY4EPZGmfDj7es5SWEfTYM9606	rogid:/+o7TcdsE/wpvm9jDN+d34DlpVo632	intact-crc:D20C59D5F67ACE1B|rigid:JFuTItrPBi8fpdLmasEBDW7jOhQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5VZF2	uniprotkb:Q7CIA2	intact:EBI-2864700|uniprotkb:Q3SXY5|uniprotkb:Q58F19|uniprotkb:Q8TD82|uniprotkb:Q8NEV3|ensembl:ENSP00000365861.3	intact:EBI-2849892|uniprotkb:Q74U75	psi-mi:mbnl2_human(display_long)|uniprotkb:MBNL2(gene name)|psi-mi:MBNL2(display_short)|uniprotkb:MBLL(gene name synonym)|uniprotkb:MBLL39(gene name synonym)|uniprotkb:MLP1(gene name synonym)|uniprotkb:Muscleblind-like protein 1(gene name synonym)|uniprotkb:Muscleblind-like protein-like(gene name synonym)|uniprotkb:Muscleblind-like protein-like 39(gene name synonym)	"psi-mi:prmc_yerpe(display_long)|uniprotkb:N5-glutamine methyltransferase PrmC(gene name synonym)|uniprotkb:""Protein-(glutamine-N5) MTase PrmC""(gene name synonym)|uniprotkb:Protein-glutamine N-methyltransferase PrmC(gene name synonym)|uniprotkb:hemK(gene name synonym)|uniprotkb:YPO2018(locus name)|uniprotkb:YP_1866(locus name)|uniprotkb:y2289(locus name)|uniprotkb:prmC(gene name)|psi-mi:prmC(display_short)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864708|imex:IM-13779-7018	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001292999.1|refseq:NP_659002.1|refseq:NP_997187.1|refseq:XP_016875798.1|refseq:XP_016875799.1|ensembl:ENSG00000139793.21(gene)|ensembl:ENST00000376673.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|rcsb pdb:2E5S|rcsb pdb:2RPP|refseq:XP_016875800.1|panther:PTHR12675(orthology-group)"	"interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004556(Modification methylase HemK)|interpro:IPR019874|interpro:IPR025714|interpro:IPR029063|refseq:WP_002211235.1|interpro:IPR040758|go:""GO:0003676""(nucleic acid binding)|go:""GO:0006415""(translational termination)|go:""GO:0032259""(methylation)|go:""GO:0036009""(protein-glutamine N-methyltransferase activity)|go:""GO:0102559""(""peptide chain release factor N(5)-glutamine methyltransferase activity"")|refseq:YP_002347004.1|interpro:IPR050320|panther:PTHR18895(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CC30+nwZA6vlfwlYu7ryqbzWq0E9606	rogid:THdPGJ4n/c8dQ78xq18i7nKkalc632	intact-crc:CCAA113120EFEBB9|rigid:0VVKw7qFqBrwJ9kCRxBXEnlWXLU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NR56	uniprotkb:Q9ZC30	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	intact:EBI-2864729|uniprotkb:Q74UP6|uniprotkb:Q7CI48|uniprotkb:A0A5P8YF72|uniprotkb:A0A3N4BFX0	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	psi-mi:q9zc30_yerpe(display_long)|uniprotkb:YPO1920(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864735|imex:IM-13779-7015	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	"interpro:IPR042186|interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR025885|interpro:IPR025949|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR037224|interpro:IPR043142|refseq:YP_002346911.1|panther:PTHR30451(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	rogid:j4ogDfMB8L4xzZc9yE8wGTi6bpQ632	intact-crc:A4820A740DF92ADF|rigid:BizlHCd+lCad5wv7beqVw0Wddg8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q74R28	uniprotkb:Q9NR56	intact:EBI-2844649|uniprotkb:Q8D1I8	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	psi-mi:ugpc_yerpe(display_long)|uniprotkb:ugpC(gene name)|psi-mi:ugpC(display_short)|uniprotkb:YPO3793(locus name)|uniprotkb:y0437(locus name)|uniprotkb:YP_3256(locus name)	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864722|imex:IM-13779-7017	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR040582|interpro:IPR015855(ABC transporter, maltose/maltodextrin import, MalK)|interpro:IPR027417|refseq:WP_002211523.1|go:""GO:0001407""(glycerophosphodiester transmembrane transport)|go:""GO:0005524""(ATP binding)|go:""GO:0008643""(carbohydrate transport)|go:""GO:0015430""(ABC-type glycerol-3-phosphate transporter activity)|go:""GO:0015794""(glycerol-3-phosphate transmembrane transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055052""(""ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing"")|interpro:IPR047641|refseq:YP_002348670.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR43875(orthology-group)"	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NtRUgbRI2HE2UzUkxbSvyMnRkao632	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	intact-crc:264677BEA11E886C|rigid:6TSg74x6HHQ81tmmmEpv3xyG478	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NR56	uniprotkb:Q8ZF52	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	intact:EBI-2854921|uniprotkb:Q0WFS8	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	psi-mi:uvrc_yerpe(display_long)|uniprotkb:uvrC(gene name)|psi-mi:uvrC(display_short)|uniprotkb:Excinuclease ABC subunit C(gene name synonym)|uniprotkb:YPO1866(locus name)|uniprotkb:y2442(locus name)|uniprotkb:YP_1527(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864715|imex:IM-13779-7014	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	"interpro:IPR050066|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004791(Excinuclease ABC, C subunit)|interpro:IPR001162(Excinuclease ABC, C subunit, C-terminal)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|refseq:WP_002220477.1|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0006974""(DNA damage response)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|interpro:IPR038476|interpro:IPR035901|interpro:IPR036876|interpro:IPR047296|panther:PTHR30562(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	rogid:2hYaQAbyVPud5UOaDjypnf1geRA632	intact-crc:3A706FA97C411F01|rigid:sf2S62SuIimVyJnqmwxFlk3l/PI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NR56	uniprotkb:Q8CLR7	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	intact:EBI-2844920|uniprotkb:Q74R33	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	psi-mi:q8clr7_yerpe(display_long)|uniprotkb:y0432(locus name)|uniprotkb:YP_3251(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864742|imex:IM-13779-7016	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	interpro:IPR032636	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	rogid:LFM9kIM6yrsqDCleXMrQPlRyJlc632	intact-crc:A16DE4407D78B6E6|rigid:VnB52ZTgw4IWTk9UJoaQUqw+xFg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NR56	uniprotkb:Q8ZG09	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	intact:EBI-2842762|uniprotkb:Q74VB1|uniprotkb:Q7CHQ5|uniprotkb:Q0WGR1	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	psi-mi:mao1_yerpe(display_long)|uniprotkb:maeA(gene name)|psi-mi:maeA(display_short)|uniprotkb:YPO1511(locus name)|uniprotkb:y2658(locus name)|uniprotkb:YP_1401(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864770|imex:IM-13779-7021	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	"interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR001891(Malic oxidoreductase)|interpro:IPR023667|go:""GO:0004470""(malic enzyme activity)|go:""GO:0004471""(""malate dehydrogenase (decarboxylating) (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006108""(malate metabolic process)|go:""GO:0008948""(oxaloacetate decarboxylase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051287""(NAD binding)|refseq:WP_002211968.1|interpro:IPR036291|interpro:IPR037062|refseq:YP_002346527.1|interpro:IPR046346|panther:PTHR23406(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	rogid:3qTE5pPHB/ePJ+WGe7JGTqu1xJA632	intact-crc:79181EA97E42CA1F|rigid:f4gfvjyq4Pl5gQgIXmNnDb/QWAk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H0W0	uniprotkb:Q9NR56	intact:EBI-2857561|uniprotkb:Q74U91|uniprotkb:Q0WFF6|uniprotkb:A0A380PDB4|uniprotkb:Q7CI92|uniprotkb:A0A384L848	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	psi-mi:a0a2u2h0w0_yerpe(display_long)|uniprotkb:YPO1997(locus name)	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864763|imex:IM-13779-7020	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR052750|interpro:IPR029058|refseq:WP_002211257.1|refseq:YP_002346982.1	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DP6LxF8YTJKUt3yW/2M2CRKvosU632	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	intact-crc:78BC61D2F4408219|rigid:ehpXGYDloBLz7e3k7HY02KY1yFQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CIX9	uniprotkb:Q9NS73	intact:EBI-2864777|uniprotkb:Q74UB9	intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718.2	psi-mi:chez_yerpe(display_long)|uniprotkb:Chemotaxis protein CheZ(gene name synonym)|uniprotkb:cheZ(gene name)|psi-mi:cheZ(display_short)|uniprotkb:YPO1681(locus name)|uniprotkb:YP_1811(locus name)|uniprotkb:y1843(locus name)	psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864782|imex:IM-13779-7023	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007439(Chemotaxis phosphatase, CheZ)|refseq:WP_002210872.1|interpro:IPR050992|go:""GO:0004721""(phosphoprotein phosphatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006935""(chemotaxis)|go:""GO:0009288""(bacterial-type flagellum)|go:""GO:0050920""(regulation of chemotaxis)|go:""GO:0097588""(archaeal or bacterial-type flagellum-dependent cell motility)|refseq:YP_002346686.1|panther:PTHR43693(orthology-group)"	"refseq:NP_001138363.1|refseq:NP_057670.2|refseq:NP_001295039.1|ensembl:ENSG00000151332.20(gene)|ensembl:ENST00000416007.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0042802""(identical protein binding)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090043""(regulation of tubulin deacetylation)|go:""GO:0140672""(ATAC complex)|mint:Q9NS73|reactome:R-HSA-3214847|reactome:R-HSA-9772755|panther:PTHR23404(orthology-group)|ensembl:ENST00000318473.11|ensembl:ENSP00000324444.5|ensembl:ENST00000359527.11|ensembl:ENSP00000352517.5|ensembl:ENSP00000399718.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7TMLT/lCdaZhYfS96RaK63ywMEA632	rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606	intact-crc:BF849ED59C933227|rigid:m3dbBU5/KI1wbUGvMwKyAbEyXl8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NR56	uniprotkb:Q0WED3	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	intact:EBI-2853357|uniprotkb:Q74TI2|uniprotkb:A0A0H2W5G4|uniprotkb:Q7CIS4|uniprotkb:A0A384LM30	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	psi-mi:q0wed3_yerpe(display_long)|uniprotkb:YPO2389(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864756|imex:IM-13779-7022	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	"interpro:IPR020846|interpro:IPR004812(Drug resistance transporter Bcr/CflA subfamily)|interpro:IPR011701(Major facilitator superfamily MFS-1)|refseq:WP_002210941.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR036259|refseq:YP_002347355.1|panther:PTHR23502(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	rogid:aXoXVPGnM1ugoV0ZdziXa2c01SM632	intact-crc:36C5397FF40F4C48|rigid:84Pt7OCFsjWiOB8EeUVBgoJwnLQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W5K7	uniprotkb:Q9NR56	intact:EBI-2840288|uniprotkb:Q74SB9|uniprotkb:Q0WD65|uniprotkb:Q7CJK1	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	psi-mi:a0a0h2w5k7_yerpe(display_long)|uniprotkb:pstC(gene name)|psi-mi:pstC(display_short)|uniprotkb:YPO2835(locus name)	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864749|imex:IM-13779-7019	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|refseq:YP_002347773.1|interpro:IPR035906|panther:PTHR42727(orthology-group)"	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kb6r/TJwxxP/f/8ZVtLRLp8IfGc632	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	intact-crc:054DE396A6A85225|rigid:8mbd7mnseNG0/Z74U/X3/icCJNU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YEP4	uniprotkb:Q9P267	intact:EBI-2842292|uniprotkb:Q74UV4|uniprotkb:Q7CHX9|uniprotkb:A0A2S9PKJ9|uniprotkb:Q0WFZ1	intact:EBI-311373|uniprotkb:A7E2B1|uniprotkb:A5HMQ4|uniprotkb:Q9NUV6|uniprotkb:Q53SR1|ensembl:ENSP00000386049.1	psi-mi:a0a5p8yep4_yerpe(display_long)|uniprotkb:Fla FV(gene name)|psi-mi:Fla FV(display_short)|uniprotkb:flaK(gene name synonym)|uniprotkb:flgE(gene name synonym)|uniprotkb:YPO1802(locus name)	psi-mi:mbd5_human(display_long)|uniprotkb:MBD5(gene name)|psi-mi:MBD5(display_short)|uniprotkb:KIAA1461(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864815|imex:IM-13779-7025	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR019776|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:WP_002211113.1|interpro:IPR037058|interpro:IPR037925|interpro:IPR053967|refseq:YP_002346797.1"	"efo:""Orphanet:178469""|efo:""Orphanet:228402""|ensembl:ENSG00000204406.14(gene)|ensembl:ENST00000407073.5(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0007399""(nervous system development)|go:""GO:0010369""(chromocenter)|go:""GO:0030496""(midbody)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0050795""(regulation of behavior)|go:""GO:0060399""(positive regulation of growth hormone receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000313(PWWP)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|reactome:R-HSA-5689603|refseq:NP_060798.2|panther:PTHR16112(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BoYVEh/qtD+LMyJcZpSfUZt9yTk632	rogid:3h6aGO+XvdJ82StRzy6BtzD6IPI9606	intact-crc:7F2D235FB3110B79|rigid:6FwNoTexClfnslpZWZqUwa6vsKw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0V0	uniprotkb:Q9P267	intact:EBI-2849272	intact:EBI-311373|uniprotkb:A7E2B1|uniprotkb:A5HMQ4|uniprotkb:Q9NUV6|uniprotkb:Q53SR1|ensembl:ENSP00000386049.1	psi-mi:q8d0v0_yerpe(display_long)|uniprotkb:fadL(gene name)|psi-mi:fadL(display_short)|uniprotkb:Outer membrane FadL protein(gene name synonym)|uniprotkb:Outer membrane flp protein(gene name synonym)|uniprotkb:y1577(locus name)	psi-mi:mbd5_human(display_long)|uniprotkb:MBD5(gene name)|psi-mi:MBD5(display_short)|uniprotkb:KIAA1461(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864796|imex:IM-13779-7024	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005017(Membrane protein involved in aromatic hydrocarbon degradation)|go:""GO:0006869""(lipid transport)|go:""GO:0009279""(cell outer membrane)"	"efo:""Orphanet:178469""|efo:""Orphanet:228402""|ensembl:ENSG00000204406.14(gene)|ensembl:ENST00000407073.5(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0007399""(nervous system development)|go:""GO:0010369""(chromocenter)|go:""GO:0030496""(midbody)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0050795""(regulation of behavior)|go:""GO:0060399""(positive regulation of growth hormone receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000313(PWWP)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|reactome:R-HSA-5689603|refseq:NP_060798.2|panther:PTHR16112(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t3ttYDBykbAjdOq/JpJE2QGeyvk632	rogid:3h6aGO+XvdJ82StRzy6BtzD6IPI9606	intact-crc:B24F22CE428C1A99|rigid:FH5dMCuDUvGoYy39BdsVVg8d3Uk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P267	uniprotkb:Q8D1M2	intact:EBI-311373|uniprotkb:A7E2B1|uniprotkb:A5HMQ4|uniprotkb:Q9NUV6|uniprotkb:Q53SR1|ensembl:ENSP00000386049.1	intact:EBI-2849599|uniprotkb:Q74Y66	psi-mi:mbd5_human(display_long)|uniprotkb:MBD5(gene name)|psi-mi:MBD5(display_short)|uniprotkb:KIAA1461(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD5(gene name synonym)	psi-mi:q8d1m2_yerpe(display_long)|uniprotkb:acrA1(gene name)|psi-mi:acrA1(display_short)|uniprotkb:YP_0101(locus name)|uniprotkb:y0287(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864789|imex:IM-13779-7028	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:178469""|efo:""Orphanet:228402""|ensembl:ENSG00000204406.14(gene)|ensembl:ENST00000407073.5(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0007399""(nervous system development)|go:""GO:0010369""(chromocenter)|go:""GO:0030496""(midbody)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0050795""(regulation of behavior)|go:""GO:0060399""(positive regulation of growth hormone receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000313(PWWP)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|reactome:R-HSA-5689603|refseq:NP_060798.2|panther:PTHR16112(orthology-group)"	"interpro:IPR006144(Secretion protein HlyD, conserved site)|interpro:IPR011053(Single hybrid motif)|go:""GO:0009306""(protein secretion)|go:""GO:0016020""(membrane)|interpro:IPR050739"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3h6aGO+XvdJ82StRzy6BtzD6IPI9606	rogid:81koSqzmbeM9XH9qVt8tsKLcazY632	intact-crc:0B9953CE4232293A|rigid:kmAQ+dgI+76y2jECsd0QWgIbvYU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PL37	uniprotkb:Q9P267	intact:EBI-2848428|uniprotkb:Q74PX4|uniprotkb:A0A0H2W7W6|uniprotkb:Q7CG52|uniprotkb:A0A384KFS5	intact:EBI-311373|uniprotkb:A7E2B1|uniprotkb:A5HMQ4|uniprotkb:Q9NUV6|uniprotkb:Q53SR1|ensembl:ENSP00000386049.1	psi-mi:a0a380pl37_yerpe(display_long)|uniprotkb:YPO0421(locus name)	psi-mi:mbd5_human(display_long)|uniprotkb:MBD5(gene name)|psi-mi:MBD5(display_short)|uniprotkb:KIAA1461(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864822|imex:IM-13779-7026	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR027463|refseq:WP_002209200.1|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:YP_002345497.1|panther:PTHR32063(orthology-group)"	"efo:""Orphanet:178469""|efo:""Orphanet:228402""|ensembl:ENSG00000204406.14(gene)|ensembl:ENST00000407073.5(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0007399""(nervous system development)|go:""GO:0010369""(chromocenter)|go:""GO:0030496""(midbody)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0050795""(regulation of behavior)|go:""GO:0060399""(positive regulation of growth hormone receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000313(PWWP)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|reactome:R-HSA-5689603|refseq:NP_060798.2|panther:PTHR16112(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eNynpfVNIWDaaydEc5eAanQErH8632	rogid:3h6aGO+XvdJ82StRzy6BtzD6IPI9606	intact-crc:BD844D6083FDC0D4|rigid:jnUiDIncOboqd6nST6gSeFVg3RU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P267	uniprotkb:Q8CZT7	intact:EBI-311373|uniprotkb:A7E2B1|uniprotkb:A5HMQ4|uniprotkb:Q9NUV6|uniprotkb:Q53SR1|ensembl:ENSP00000386049.1	intact:EBI-2864803|uniprotkb:Q74QN2	psi-mi:mbd5_human(display_long)|uniprotkb:MBD5(gene name)|psi-mi:MBD5(display_short)|uniprotkb:KIAA1461(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD5(gene name synonym)	psi-mi:q8czt7_yerpe(display_long)|uniprotkb:mdlB6(gene name)|psi-mi:mdlB6(display_short)|uniprotkb:YP_3431(locus name)|uniprotkb:y3423(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864808|imex:IM-13779-7027	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:178469""|efo:""Orphanet:228402""|ensembl:ENSG00000204406.14(gene)|ensembl:ENST00000407073.5(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0007399""(nervous system development)|go:""GO:0010369""(chromocenter)|go:""GO:0030496""(midbody)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0050795""(regulation of behavior)|go:""GO:0060399""(positive regulation of growth hormone receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000313(PWWP)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|reactome:R-HSA-5689603|refseq:NP_060798.2|panther:PTHR16112(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR036640|interpro:IPR039421"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3h6aGO+XvdJ82StRzy6BtzD6IPI9606	rogid:el+ZGNoPu+tlko8ZJA2/rbnPJOU632	intact-crc:39921A99431A4A69|rigid:16UWldQ8iFmtatpsxXKM2Qkcz48	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CIZ7	uniprotkb:P27448	intact:EBI-2843304|uniprotkb:Q74UE8|uniprotkb:A0A384KZ59|uniprotkb:B4X9S5|uniprotkb:A0A0H2W3L1|uniprotkb:A0A5P8YGN2	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	psi-mi:q7ciz7_yerpe(display_long)|uniprotkb:appA(gene name)|psi-mi:appA(display_short)|uniprotkb:YPO1648(locus name)	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864857|imex:IM-13779-7033	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033379|interpro:IPR000560(Histidine acid phosphatase)|interpro:IPR029033|go:""GO:0003993""(acid phosphatase activity)|go:""GO:0008707""(4-phytase activity)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0050308""(sugar-phosphatase activity)|refseq:WP_002210903.1|refseq:YP_002346658.1|interpro:IPR050645|panther:PTHR11567(orthology-group)"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:LJ8BlvMBlhdzSOKMptIEdIH68xQ632	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	intact-crc:B08AC437F3F96144|rigid:9IJMXM3jYQjnOrLc3L4GY92bW9w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P267	uniprotkb:Q8ZDG9	intact:EBI-311373|uniprotkb:A7E2B1|uniprotkb:A5HMQ4|uniprotkb:Q9NUV6|uniprotkb:Q53SR1|ensembl:ENSP00000386049.1	intact:EBI-2846543|uniprotkb:Q0WDT3	psi-mi:mbd5_human(display_long)|uniprotkb:MBD5(gene name)|psi-mi:MBD5(display_short)|uniprotkb:KIAA1461(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD5(gene name synonym)	psi-mi:lipb_yerpe(display_long)|uniprotkb:lipB(gene name)|psi-mi:lipB(display_short)|uniprotkb:Lipoate-protein ligase B(gene name synonym)|uniprotkb:Lipoyl/octanoyl transferase(gene name synonym)|uniprotkb:Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase(gene name synonym)|uniprotkb:YPO2599(locus name)|uniprotkb:y1173(locus name)|uniprotkb:YP_1114(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864829|imex:IM-13779-7029	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:178469""|efo:""Orphanet:228402""|ensembl:ENSG00000204406.14(gene)|ensembl:ENST00000407073.5(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0007399""(nervous system development)|go:""GO:0010369""(chromocenter)|go:""GO:0030496""(midbody)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0050795""(regulation of behavior)|go:""GO:0060399""(positive regulation of growth hormone receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000313(PWWP)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|reactome:R-HSA-5689603|refseq:NP_060798.2|panther:PTHR16112(orthology-group)"	"interpro:IPR004143(Biotin/lipoate A/B protein ligase)|interpro:IPR000544(Lipoate-protein ligase B)|interpro:IPR020605|refseq:WP_002218201.1|go:""GO:0005737""(cytoplasm)|go:""GO:0033819""(""lipoyl(octanoyl) transferase activity"")|interpro:IPR045864|panther:PTHR10993(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3h6aGO+XvdJ82StRzy6BtzD6IPI9606	rogid:hReS04IYeo8x9cJJiZM0jH7goUg632	intact-crc:89B9457040329EA6|rigid:fokOHKDiM9R1XcoEYA0nEFFzDf4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P267	uniprotkb:Q7CGS4	intact:EBI-311373|uniprotkb:A7E2B1|uniprotkb:A5HMQ4|uniprotkb:Q9NUV6|uniprotkb:Q53SR1|ensembl:ENSP00000386049.1	intact:EBI-2846699|uniprotkb:Q74QG3	psi-mi:mbd5_human(display_long)|uniprotkb:MBD5(gene name)|psi-mi:MBD5(display_short)|uniprotkb:KIAA1461(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD5(gene name synonym)	psi-mi:e4pd_yerpe(display_long)|uniprotkb:epd(gene name)|psi-mi:epd(display_short)|uniprotkb:YPO0922(locus name)|uniprotkb:y3309(locus name)|uniprotkb:YP_3518(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864836|imex:IM-13779-7032	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:178469""|efo:""Orphanet:228402""|ensembl:ENSG00000204406.14(gene)|ensembl:ENST00000407073.5(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0007399""(nervous system development)|go:""GO:0010369""(chromocenter)|go:""GO:0030496""(midbody)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0050795""(regulation of behavior)|go:""GO:0060399""(positive regulation of growth hormone receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000313(PWWP)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|reactome:R-HSA-5689603|refseq:NP_060798.2|panther:PTHR16112(orthology-group)"	"interpro:IPR006422(D-erythrose-4-phosphate dehydrogenase)|interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|refseq:WP_002209964.1|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0008615""(pyridoxine biosynthetic process)|go:""GO:0042823""(pyridoxal phosphate biosynthetic process)|go:""GO:0048001""(erythrose-4-phosphate dehydrogenase activity)|go:""GO:0051287""(NAD binding)|interpro:IPR036291|refseq:YP_002345970.1|panther:PTHR43148(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3h6aGO+XvdJ82StRzy6BtzD6IPI9606	rogid:PzUDobm36XTKelGxo57qKYNpTgk632	intact-crc:A2C183609CFEDB19|rigid:W9Usu8youNHPX8TykrntUNRV4jE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43243	uniprotkb:Q8D068	intact:EBI-352602|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5|ensembl:ENSP00000378284.3|ensembl:ENSP00000482895.1	intact:EBI-2846153|uniprotkb:Q74VD0	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	psi-mi:q8d068_yerpe(display_long)|uniprotkb:uup3(gene name)|psi-mi:uup3(display_short)|uniprotkb:YP_1381(locus name)|uniprotkb:y2677(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864843|imex:IM-13779-7030	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000015479.20(gene)|ensembl:ENST00000394805.8(transcript)|ensembl:ENST00000618441.5(transcript)|go:""GO:0001825""(blastocyst formation)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003170""(heart valve development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005634""(nucleus)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_001181885.1|refseq:NP_001269207.1|refseq:NP_061322.2|refseq:NP_954659.1|efo:""Orphanet:600""|efo:""Orphanet:803""|panther:PTHR15592(orthology-group)"	"interpro:IPR032781|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR050611"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	rogid:uq/st091dJjwV1JggBt3SaIlbSQ632	intact-crc:2000EEE47F445821|rigid:KzUnYbWLLVjRH9R3QEtQXwDf5NE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27448	uniprotkb:Q8D1K6	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	intact:EBI-2860302	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	psi-mi:q8d1k6_yerpe(display_long)|uniprotkb:wzzE(gene name)|psi-mi:wzzE(display_short)|uniprotkb:y0363(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864850|imex:IM-13779-7031	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"interpro:IPR003856(Lipopolysaccharide biosynthesis)|interpro:IPR032895|interpro:IPR050445|go:""GO:0005886""(plasma membrane)|go:""GO:0009246""(enterobacterial common antigen biosynthetic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	rogid:dnS1WOEnus6FSM+v/AeLTGNGO08632	intact-crc:1329BA992CA01D23|rigid:2VvXJUan3HgjqB2egKaNcIUzJ+A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27448	uniprotkb:A0A380PEP4	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	intact:EBI-2855773|uniprotkb:Q7CIE5|uniprotkb:Q0WF50	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	psi-mi:a0a380pep4_yerpe(display_long)|uniprotkb:YPO2110(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864864|imex:IM-13779-7037	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|refseq:WP_002211719.1|refseq:YP_002347088.1|interpro:IPR045404	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	rogid:XRBt2yNcXiRw7G80v1I7gR997oU632	intact-crc:697D8A445FEAB545|rigid:7pxh6aOi6dWUSrqNHvNQGqRwiw8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27448	uniprotkb:A0A380PLQ4	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	intact:EBI-2841937|uniprotkb:Q74RN6|uniprotkb:Q7CGH9|uniprotkb:A0A0H2W839	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	psi-mi:a0a380plq4_yerpe(display_long)|uniprotkb:parC(gene name)|psi-mi:parC(display_short)|uniprotkb:Topoisomerase IV subunit A(gene name synonym)|uniprotkb:YPO0671(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864871|imex:IM-13779-7034	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006265""(DNA topological change)|go:""GO:0007059""(chromosome segregation)|go:""GO:0009330""(""DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex"")|go:""GO:0019897""(extrinsic component of plasma membrane)|go:""GO:0034335""(DNA negative supercoiling activity)|refseq:WP_002212178.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR035516|interpro:IPR005742(DNA topoisomerase IV, subunit A, Gram-negative)|refseq:YP_002345739.1|interpro:IPR050220|panther:PTHR43493(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	rogid:IvRCQJ0mieNBBTNb7i1F6inwn/8632	intact-crc:C3F0C63D8C70FC96|rigid:9I32LeWtsBoksyNjm6EaRB5U89w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27448	uniprotkb:A0A0H2W0Z5	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	intact:EBI-2844986|uniprotkb:Q74Y40|uniprotkb:Q0WKG8|uniprotkb:Q7CFX1|uniprotkb:A0A380PIN3|uniprotkb:A0A384LBS1	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	psi-mi:a0a0h2w0z5_yerpe(display_long)|uniprotkb:YPO0134(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864878|imex:IM-13779-7038	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR023323|interpro:IPR023319|interpro:IPR018974|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR044146|refseq:WP_002208916.1|go:""GO:0003676""(nucleic acid binding)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|interpro:IPR055179|interpro:IPR032639|interpro:IPR037027|interpro:IPR041692|refseq:YP_002345220.1|interpro:IPR050437"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	rogid:ttlZGvCMP/bbGv1PpYdheTErKIk632	intact-crc:08EB40CF0B090752|rigid:kxWkObmKd+gpQpJQItXbInODHFA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:P27448	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864885|imex:IM-13779-7035	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	intact-crc:94CE75D5F28C7963|rigid:hvRHgueK3BVgAzP7EJwDwraPKss	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZDX4	uniprotkb:Q15691	intact:EBI-2854297|uniprotkb:Q0WEA0	intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721.5	psi-mi:btuc_yerpe(display_long)|uniprotkb:btuC(gene name)|psi-mi:btuC(display_short)|uniprotkb:YPO2425(locus name)|uniprotkb:y1914(locus name)|uniprotkb:YP_2212(locus name)	psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864899|imex:IM-13779-7039	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023691|interpro:IPR000522(Bacterial transport system permease protein)|refseq:WP_002220283.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015889""(cobalamin transport)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0090482""(vitamin transmembrane transporter activity)|interpro:IPR037294|refseq:YP_002347388.1|panther:PTHR30472(orthology-group)"	"refseq:NP_036457.1|refseq:XP_011526998.1|dip:DIP-38018N|ensembl:ENSG00000101367.9(gene)|ensembl:ENST00000375571.6(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0001578""(microtubule bundle formation)|go:""GO:0003723""(RNA binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0005925""(focal adhesion)|go:""GO:0008104""(protein localization)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030981""(cortical microtubule cytoskeleton)|go:""GO:0031110""(regulation of microtubule polymerization or depolymerization)|go:""GO:0031115""(negative regulation of microtubule polymerization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0045296""(cadherin binding)|go:""GO:0031253""(cell projection membrane)|go:""GO:0035371""(microtubule plus-end)|go:""GO:0035372""(protein localization to microtubule)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051233""(spindle midzone)|go:""GO:0051301""(cell division)|go:""GO:0051315""(attachment of mitotic spindle microtubules to kinetochore)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0097431""(mitotic spindle pole)|go:""GO:1902480""(protein localization to mitotic spindle)|go:""GO:1902888""(protein localization to astral microtubule)|go:""GO:1905515""(non-motile cilium assembly)|go:""GO:1905721""(mitotic spindle astral microtubule end)|go:""GO:1990498""(mitotic spindle microtubule)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|panther:PTHR10623(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:VbgN61SjIkXmwpfgZz3xo6Um6Cc632	rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606	intact-crc:A06A435584A8738A|rigid:SDr9qa37EYgP0gFbRJ8pYYgcX/A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YGL8	uniprotkb:Q15691	intact:EBI-2845909|uniprotkb:Q74VS1|uniprotkb:Q0WH41|uniprotkb:Q7CHI6|uniprotkb:A0A384L3E0	intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721.5	psi-mi:a0a5p8ygl8_yerpe(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:YPO1374(locus name)	psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864892|imex:IM-13779-7036	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0019430""(removal of superoxide radicals)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_002211341.1|interpro:IPR036188|refseq:YP_002346397.1|interpro:IPR050097|panther:PTHR48105(orthology-group)"	"refseq:NP_036457.1|refseq:XP_011526998.1|dip:DIP-38018N|ensembl:ENSG00000101367.9(gene)|ensembl:ENST00000375571.6(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0001578""(microtubule bundle formation)|go:""GO:0003723""(RNA binding)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0005925""(focal adhesion)|go:""GO:0008104""(protein localization)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030981""(cortical microtubule cytoskeleton)|go:""GO:0031110""(regulation of microtubule polymerization or depolymerization)|go:""GO:0031115""(negative regulation of microtubule polymerization)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0045296""(cadherin binding)|go:""GO:0031253""(cell projection membrane)|go:""GO:0035371""(microtubule plus-end)|go:""GO:0035372""(protein localization to microtubule)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042802""(identical protein binding)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051233""(spindle midzone)|go:""GO:0051301""(cell division)|go:""GO:0051315""(attachment of mitotic spindle microtubules to kinetochore)|go:""GO:0071539""(protein localization to centrosome)|go:""GO:0097431""(mitotic spindle pole)|go:""GO:1902480""(protein localization to mitotic spindle)|go:""GO:1902888""(protein localization to astral microtubule)|go:""GO:1905515""(non-motile cilium assembly)|go:""GO:1905721""(mitotic spindle astral microtubule end)|go:""GO:1990498""(mitotic spindle microtubule)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|panther:PTHR10623(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:lNjtMW37Ur6Z7pzA6LzMVzq9VCU632	rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606	intact-crc:49836C68477D6506|rigid:dp542kmhzPNh1QmWR8y0knXsGy4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27816	uniprotkb:Q8ZFX5	intact:EBI-715255|uniprotkb:Q59FT2|uniprotkb:Q68D74|uniprotkb:Q6ZUW9|uniprotkb:Q96NS9|uniprotkb:Q13082|uniprotkb:Q96A76|uniprotkb:Q86V26|ensembl:ENSP00000353375.6	intact:EBI-2851740|uniprotkb:Q0WGM4	psi-mi:map4_human(display_long)|uniprotkb:MAP4(gene name)|psi-mi:MAP4(display_short)	psi-mi:hisx_yerpe(display_long)|uniprotkb:hisD(gene name)|psi-mi:hisD(display_short)|uniprotkb:YPO1548(locus name)|uniprotkb:y2621(locus name)|uniprotkb:YP_1437(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864920|imex:IM-13779-7042	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002366.2|refseq:NP_001127836.1|refseq:NP_112147.2|ensembl:ENSG00000047849.22(gene)|ensembl:ENST00000360240.10(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0005930""(axoneme)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030424""(axon)|go:""GO:0031175""(neuron projection development)|go:""GO:0043005""(neuron projection)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0051012""(microtubule sliding)|go:""GO:0051294""(establishment of spindle orientation)|go:""GO:0051301""(cell division)|go:""GO:0061523""(cilium disassembly)|go:""GO:0072686""(mitotic spindle)|go:""GO:0140778""(microtubule stabilizing activity)|go:""GO:1902856""(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027324|mint:P27816|panther:PTHR11501(orthology-group)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR001692(Histidinol dehydrogenase)|interpro:IPR022695|interpro:IPR012131(Histidinol dehydrogenase, prokaryotic)|refseq:WP_002211895.1|go:""GO:0000105""(L-histidine biosynthetic process)|go:""GO:0004399""(histidinol dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0051287""(NAD binding)|refseq:YP_002346564.1|panther:PTHR21256(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rBf82W3kFCo+2UklK5WHO3MWjV09606	rogid:aXT+/ioqFLvYG1ayljhfqLE1ikU632	intact-crc:5AF9802034BD794B|rigid:OVJ7EKND8722CCQmLaSdH7jlUgU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:P27816	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-715255|uniprotkb:Q59FT2|uniprotkb:Q68D74|uniprotkb:Q6ZUW9|uniprotkb:Q96NS9|uniprotkb:Q13082|uniprotkb:Q96A76|uniprotkb:Q86V26|ensembl:ENSP00000353375.6	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:map4_human(display_long)|uniprotkb:MAP4(gene name)|psi-mi:MAP4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864913|imex:IM-13779-7044	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:NP_002366.2|refseq:NP_001127836.1|refseq:NP_112147.2|ensembl:ENSG00000047849.22(gene)|ensembl:ENST00000360240.10(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0005930""(axoneme)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030424""(axon)|go:""GO:0031175""(neuron projection development)|go:""GO:0043005""(neuron projection)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0051012""(microtubule sliding)|go:""GO:0051294""(establishment of spindle orientation)|go:""GO:0051301""(cell division)|go:""GO:0061523""(cilium disassembly)|go:""GO:0072686""(mitotic spindle)|go:""GO:0140778""(microtubule stabilizing activity)|go:""GO:1902856""(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027324|mint:P27816|panther:PTHR11501(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:rBf82W3kFCo+2UklK5WHO3MWjV09606	intact-crc:276DBBD2EA712516|rigid:fLd4WbDPMWKJ9H1nMbaGC7sBhlM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5LB76	uniprotkb:Q8IZL2	intact:EBI-2864942|uniprotkb:O68747|uniprotkb:Q74YN6|uniprotkb:A0A1U8QJZ3|uniprotkb:Q7ARE4|uniprotkb:A0A5P8YLZ6|uniprotkb:A0A0H2W1T2	intact:EBI-2864946|uniprotkb:Q8IUL3|uniprotkb:Q96JK6|uniprotkb:Q6AI23|uniprotkb:Q6Y3A3|uniprotkb:A7MD26|ensembl:ENSP00000434552.1	psi-mi:a0a3g5lb76_yerpe(display_long)|uniprotkb:YPMT1.29c(locus name)	psi-mi:maml2_human(display_long)|uniprotkb:MAML2(gene name)|psi-mi:MAML2(display_short)|uniprotkb:KIAA1819(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864939|imex:IM-13779-7040	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003115(ParB-like nuclease)|refseq:NP_395367.1|refseq:YP_093908.1|refseq:WP_002228791.1|interpro:IPR050336|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|interpro:IPR036086"	"refseq:NP_115803.1|ensembl:ENSG00000184384.15(gene)|ensembl:ENST00000524717.6(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007221""(positive regulation of transcription of Notch receptor target)|go:""GO:0016607""(nuclear speck)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR019082|interpro:IPR046369|interpro:IPR046370|interpro:IPR048452|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|panther:PTHR15692(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:D1BHz+NuY+9Ir+fV6Ces4NaKnsQ632	rogid:lGOHJ8BX0kDKDCznzP7Xi9pCliI9606	intact-crc:771AF6CBE37533B4|rigid:3ccDYKMJMSpk/DO+Q4zhgQDbzsI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27816	uniprotkb:A0A2S9PFE9	intact:EBI-715255|uniprotkb:Q59FT2|uniprotkb:Q68D74|uniprotkb:Q6ZUW9|uniprotkb:Q96NS9|uniprotkb:Q13082|uniprotkb:Q96A76|uniprotkb:Q86V26|ensembl:ENSP00000353375.6	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	psi-mi:map4_human(display_long)|uniprotkb:MAP4(gene name)|psi-mi:MAP4(display_short)	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864906|imex:IM-13779-7043	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002366.2|refseq:NP_001127836.1|refseq:NP_112147.2|ensembl:ENSG00000047849.22(gene)|ensembl:ENST00000360240.10(transcript)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0005930""(axoneme)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030424""(axon)|go:""GO:0031175""(neuron projection development)|go:""GO:0043005""(neuron projection)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0051012""(microtubule sliding)|go:""GO:0051294""(establishment of spindle orientation)|go:""GO:0051301""(cell division)|go:""GO:0061523""(cilium disassembly)|go:""GO:0072686""(mitotic spindle)|go:""GO:0140778""(microtubule stabilizing activity)|go:""GO:1902856""(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027324|mint:P27816|panther:PTHR11501(orthology-group)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rBf82W3kFCo+2UklK5WHO3MWjV09606	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	intact-crc:F93AE4900986E7E1|rigid:cV7jJk1+RbXjXN5MYjnN4/d8ohE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96JK9	uniprotkb:A0A2U2GWJ4	intact:EBI-1043855|intact:EBI-28973985|uniprotkb:B2RNU9|uniprotkb:B3KVV7|uniprotkb:E7EVW8|ensembl:ENSP00000421180.1	intact:EBI-2864927|uniprotkb:Q74QE3|uniprotkb:Q0WIJ3|uniprotkb:Q7CGW5|uniprotkb:A0A384KQE8|uniprotkb:A0A3N4B697	psi-mi:maml3_human(display_long)|uniprotkb:MAML3(gene name)|psi-mi:MAML3(display_short)|uniprotkb:KIAA1816(gene name synonym)	psi-mi:a0a2u2gwj4_yerpe(display_long)|uniprotkb:agaY(gene name)|psi-mi:agaY(display_short)|uniprotkb:kba(gene name synonym)|uniprotkb:Tagatose-bisphosphate aldolase(gene name synonym)|uniprotkb:D-tagatose-bisphosphate aldolase class II(gene name synonym)|uniprotkb:YPO0844(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864932|imex:IM-13779-7041	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_061187.2|ensembl:ENSG00000196782.13(gene)|ensembl:ENST00000509479.6(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007221""(positive regulation of transcription of Notch receptor target)|go:""GO:0016607""(nuclear speck)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR019082|interpro:IPR046369|interpro:IPR046370|interpro:IPR048455|interpro:IPR048456|mint:Q96JK9|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|panther:PTHR15692(orthology-group)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000771(Ketose-bisphosphate aldolase, class-II)|interpro:IPR011288(Class II aldolase, tagatose bisphosphate)|refseq:WP_002209888.1|interpro:IPR050246|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009025""(tagatose-bisphosphate aldolase activity)|go:""GO:2001059""(D-tagatose 6-phosphate catabolic process)|refseq:YP_002345895.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6i+Dc9Y+mL9UVF/Du2ooTKwbPjo9606	rogid:ndULoV2Jmor4ekrUTyX1sNI8WAs632	intact-crc:D0053C5589FF7DE5|rigid:7L/b0j7Kk1jXdJsPNEbKeAcXBdI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P69974	intact:EBI-2805038	intact:EBI-2842860|uniprotkb:Q00927|uniprotkb:Q663H9	-	psi-mi:ysck_yerpe(display_long)|uniprotkb:yscK(gene name)|psi-mi:yscK(display_short)|uniprotkb:lcrKB(gene name synonym)|uniprotkb:Low calcium response locus protein KB(gene name synonym)|uniprotkb:YPCD1.60(locus name)|uniprotkb:y5018(locus name)|uniprotkb:y0021(locus name)|uniprotkb:YP_pCD23(locus name)	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864960|imex:IM-13779-7048	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR009510(YOP secretion, YscK)|refseq:NP_395194.1|refseq:NP_857722.1|refseq:NP_857917.1|refseq:WP_002361471.1|mint:P69974	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Qop37NpVvPcunbQHHIyWE4Qiohw632	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	intact-crc:022C99224021C83E|rigid:uX9V5khqmdJGM3v6lNv/8a/Bt4E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2805038	uniprotkb:Q8D0F7	-	intact:EBI-2858387|uniprotkb:Q74U34	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	psi-mi:q8d0f7_yerpe(display_long)|uniprotkb:YP_1918(locus name)|uniprotkb:rnd(gene name)|psi-mi:rnd(display_short)|uniprotkb:y2235(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864974|imex:IM-13779-7049	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"interpro:IPR002562(3'-5' exonuclease)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR010997(HRDC-like)|interpro:IPR006292(Ribonuclease D)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR051086|go:""GO:0000166""(nucleotide binding)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0033890""(ribonuclease D activity)|go:""GO:0042780""(tRNA 3'-end processing)|interpro:IPR036397|interpro:IPR048579|interpro:IPR044876"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	rogid:uepiYyTWB1eAu/pzLVjmyvmm7/w632	intact-crc:13F8B0BB33A767C9|rigid:RTxeQFo2HagsU1PtcfkTUZunBes	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2805038	uniprotkb:Q8CZU2	-	intact:EBI-2843382	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	psi-mi:q8czu2_yerpe(display_long)|uniprotkb:yapH(gene name)|psi-mi:yapH(display_short)|uniprotkb:y3396(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864981|imex:IM-13779-7046	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"interpro:IPR024973|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0019867""(outer membrane)|interpro:IPR036709|interpro:IPR043990|interpro:IPR050909"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	rogid:w2l6qUtIv4INNGQ9HeM84bFptXU632	intact-crc:904488EC328D5AC3|rigid:AqoNpcilO1BruazT8KwVNUzKcZs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YHK6	intact:EBI-2805038	intact:EBI-2856093|uniprotkb:A0A0H2W5D6|uniprotkb:Q74SI7|uniprotkb:Q7CJF5|uniprotkb:A0A384KU48	-	psi-mi:a0a5p8yhk6_yerpe(display_long)|uniprotkb:cysK(gene name)|psi-mi:cysK(display_short)|uniprotkb:cysZ(gene name synonym)|uniprotkb:YPO2992(locus name)	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864988|imex:IM-13779-7047	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR005856(Cysteine synthase K/M)|interpro:IPR005859(Cysteine synthase A)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR050214|refseq:WP_002222180.1|go:""GO:0004124""(cysteine synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006535""(cysteine biosynthetic process from serine)|go:""GO:0080146""(L-cysteine desulfhydrase activity)|interpro:IPR036052|refseq:YP_002347916.1|panther:PTHR10314(orthology-group)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UrC5dh7j9HnS/MZkY6/7kxZcpME632	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	intact-crc:66FFE89399EF3E95|rigid:y5W4aAiKFHO4iOzelolsjaWifNY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17778	intact:EBI-2805038	intact:EBI-2842665|uniprotkb:O68701	-	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2864967|imex:IM-13779-7045	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	intact-crc:C71A219E14B5CD3E|rigid:2eIEbJVHhZXP4rkdZIQ88DTvcu0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86UL8	uniprotkb:Q8CLU2	intact:EBI-311035|uniprotkb:O60434|uniprotkb:O60510|uniprotkb:Q86UI7|uniprotkb:Q9NP44|uniprotkb:Q9UDQ5|uniprotkb:Q9UDU1|uniprotkb:A4D1C1|uniprotkb:A7E2C3|intact:EBI-28973920|ensembl:ENSP00000346151.4	intact:EBI-2848736	psi-mi:magi2_human(display_long)|uniprotkb:MAGI2(gene name)|psi-mi:MAGI2(display_short)|uniprotkb:KIAA0705(gene name synonym)|uniprotkb:ACVRINP1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein A(gene name synonym)|uniprotkb:AIP1(gene name synonym)	psi-mi:q8clu2_yerpe(display_long)|uniprotkb:y0226(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865014|imex:IM-13779-7053	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:656""|ensembl:ENSG00000187391.23(gene)|ensembl:ENST00000354212.9(transcript)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0002092""(positive regulation of receptor internalization)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005770""(late endosome)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007165""(signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014069""(postsynaptic density)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0031697""(beta-1 adrenergic receptor binding)|go:""GO:0032926""(negative regulation of activin receptor signaling pathway)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036057""(slit diaphragm)|go:""GO:0038180""(nerve growth factor signaling pathway)|go:""GO:0043113""(receptor clustering)|go:""GO:0045202""(synapse)|go:""GO:0046332""(SMAD binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0070699""(type II activin receptor binding)|go:""GO:0072015""(podocyte development)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0097546""(ciliary base)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR036020|interpro:IPR036034|mint:Q86UL8|rcsb pdb:1UEP|rcsb pdb:1UEQ|rcsb pdb:1UEW|rcsb pdb:1UJV|rcsb pdb:1WFV|reactome:R-HSA-373753|refseq:NP_001288057.1|refseq:NP_036433.2|panther:PTHR10316(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/uTMSMqB1wrlyHj2P9OVVBCpWcY9606	rogid:5HyUa7JBgXp2+pRD7HwFGE0KIds632	intact-crc:6948A30ACD169C56|rigid:kt/hUQJMKe0HPk4ykmGIGhzqJb4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YCY9	intact:EBI-2805038	intact:EBI-2864995|uniprotkb:Q74QA3|uniprotkb:A0A0H2W882|uniprotkb:Q7CGU0|uniprotkb:A0A384LBV3	-	psi-mi:a0a5p8ycy9_yerpe(display_long)|uniprotkb:int(gene name)|psi-mi:int(display_short)|uniprotkb:YPO0887(locus name)	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865000|imex:IM-13779-7050	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013762(Integrase-like, catalytic core, phage)|interpro:IPR002104(Integrase, catalytic core, phage)|interpro:IPR025166|interpro:IPR053876|refseq:WP_002209929.1|interpro:IPR050808|interpro:IPR038488|go:""GO:0003677""(DNA binding)|go:""GO:0006310""(DNA recombination)|go:""GO:0015074""(DNA integration)|interpro:IPR010998(Integrase, Lamba-type, N-terminal)|refseq:YP_002345935.1|panther:PTHR30629(orthology-group)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/3H0yERWoVSPh3DLvbTjYj+MWCw632	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	intact-crc:0381F3939A9B4D3B|rigid:FlZj73TAOFAS/RCcKxuJDKgRXuc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA84	intact:EBI-2805038	intact:EBI-2842602|uniprotkb:Q0WA86	-	psi-mi:capp_yerpe(display_long)|uniprotkb:ppc(gene name)|psi-mi:ppc(display_short)|uniprotkb:YPO3929(locus name)|uniprotkb:y0308(locus name)|uniprotkb:YP_3121(locus name)	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865007|imex:IM-13779-7052	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033129|interpro:IPR021135|interpro:IPR018129|interpro:IPR022805|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006107""(oxaloacetate metabolic process)|go:""GO:0008964""(phosphoenolpyruvate carboxylase activity)|go:""GO:0015977""(carbon fixation)|refseq:WP_002209491.1|refseq:YP_002348802.1|panther:PTHR30523(orthology-group)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aPbGF+uF/gTYbtmc4Mkr1Ys0jNc632	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	intact-crc:E43962053353A939|rigid:+pUJXeq9RFi16yD94pbbxrcNqJY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCI5	uniprotkb:Q8ZAW9	intact:EBI-949966|uniprotkb:Q5JXC7|uniprotkb:Q86TG0|uniprotkb:Q8TD92|uniprotkb:Q9H216|ensembl:ENSP00000354912.2	intact:EBI-2865021|uniprotkb:Q0WAZ0	psi-mi:mage1_human(display_long)|uniprotkb:MAGE-E1 antigen(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated protein 1(gene name synonym)|uniprotkb:MAGEE1(gene name)|psi-mi:MAGEE1(display_short)|uniprotkb:HCA1(gene name synonym)|uniprotkb:KIAA1587(gene name synonym)|uniprotkb:Alpha-dystrobrevin-associated MAGE Protein(gene name synonym)	psi-mi:msrp_yerpe(display_long)|uniprotkb:msrP(gene name)|psi-mi:msrP(display_short)|uniprotkb:YPO3662(locus name)|uniprotkb:YP_3884(locus name)|uniprotkb:y0205(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865026|imex:IM-13779-7051	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_065983.1|ensembl:ENSG00000198934.5(gene)|ensembl:ENST00000361470.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0005634""(nucleus)|go:""GO:0005886""(plasma membrane)|go:""GO:0030425""(dendrite)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR002190(MAGE protein)|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|panther:PTHR11736(orthology-group)"	"interpro:IPR000572(Oxidoreductase, molybdopterin binding)|interpro:IPR022867|refseq:WP_002210073.1|go:""GO:0016672""(oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor)|go:""GO:0030091""(protein repair)|go:""GO:0042597""(periplasmic space)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR036374|refseq:YP_002348548.1|panther:PTHR43032(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ou5B+9t61iyCM1kS8+9EHUkaXMw9606	rogid:7OHEBPek5esFzyIjzAJokEc382w632	intact-crc:7283EB3783EA6A69|rigid:bkEoM3zQjJRAEvDoooLsu0xN9Xs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95819	uniprotkb:Q8ZAQ2	intact:EBI-2511133|intact:EBI-28985706|uniprotkb:O75172|uniprotkb:Q9NST7|uniprotkb:E7ESS2|ensembl:ENSP00000314363.6	intact:EBI-2860892|uniprotkb:Q0WAR9	psi-mi:m4k4_human(display_long)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym)	psi-mi:thic_yerpe(display_long)|uniprotkb:thiC(gene name)|psi-mi:thiC(display_short)|uniprotkb:YP_3102(locus name)|uniprotkb:Hydroxymethylpyrimidine phosphate synthase(gene name synonym)|uniprotkb:YPO3739(locus name)|uniprotkb:y0491(locus name)|uniprotkb:Thiamine biosynthesis protein ThiC(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865040|imex:IM-13779-7057	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_663719.2|refseq:NP_001229488.1|refseq:NP_004825.3|refseq:NP_663720.1|ensembl:ENSG00000071054.17(gene)|ensembl:ENST00000347699.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001953""(negative regulation of cell-matrix adhesion)|go:""GO:0004111""(creatine kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008017""(microtubule binding)|go:""GO:0008349""(MAP kinase kinase kinase kinase activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032014""(positive regulation of ARF protein signal transduction)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046328""(regulation of JNK cascade)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120183""(positive regulation of focal adhesion disassembly)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR051700|mint:O95819|rcsb pdb:4OBO|rcsb pdb:4OBP|rcsb pdb:4OBQ|rcsb pdb:4RVT|rcsb pdb:4U3Y|rcsb pdb:4U3Z|rcsb pdb:4U40|rcsb pdb:4U41|rcsb pdb:4U42|rcsb pdb:4U43|rcsb pdb:4U44|rcsb pdb:4U45|rcsb pdb:4ZK5|rcsb pdb:4ZP5|rcsb pdb:5DI1|rcsb pdb:5J95|rcsb pdb:5W5Q|reactome:R-HSA-2559580|panther:PTHR48015(orthology-group)"	"interpro:IPR002817(Thiamine biosynthesis protein ThiC)|refseq:WP_002210682.1|interpro:IPR025747|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0016830""(carbon-carbon lyase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR038521|interpro:IPR037509|refseq:YP_002348619.1|panther:PTHR30557(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wEXGp6vM4HhwldyeQJKvEdilMpQ9606	rogid:RVZL9aFEqXV/KORpQabcnqvxVkE632	intact-crc:ED4B0B8D715E4B8E|rigid:9c7X3oR8uYT2lTE7UGvhNylHE48	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60664	uniprotkb:A0A454XXH7	intact:EBI-725795|uniprotkb:Q53G77|uniprotkb:Q9BS03|uniprotkb:Q9UBD7|uniprotkb:Q9UP92|uniprotkb:A8K4Y9|uniprotkb:K7EQF4|intact:EBI-11103673|ensembl:ENSP00000221957.3	intact:EBI-2851240|uniprotkb:Q74Y15|uniprotkb:A0A0H2W158|uniprotkb:Q7CFV5|uniprotkb:A0A384K924	psi-mi:plin3_human(display_long)|uniprotkb:Cargo selection protein TIP47(gene name synonym)|uniprotkb:47 kDa mannose 6-phosphate receptor-binding protein(gene name synonym)|uniprotkb:Placental protein 17(gene name synonym)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short)|uniprotkb:TIP47(gene name synonym)|uniprotkb:M6PRBP1(gene name synonym)|uniprotkb:Mannose-6-phosphate receptor-binding protein 1(gene name synonym)	psi-mi:a0a454xxh7_yerpe(display_long)|uniprotkb:YPO0168(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865033|imex:IM-13779-7054	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001157666.1|refseq:NP_001157661.1|refseq:NP_005808.3|ensembl:ENSG00000105355.9(gene)|ensembl:ENST00000221957.9(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0010008""(endosome membrane)|go:""GO:0010890""(positive regulation of triglyceride storage)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019915""(lipid storage)|go:""GO:0030133""(transport vesicle)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0045296""(cadherin binding)|go:""GO:1905691""(lipid droplet disassembly)|interpro:IPR004279(Perilipin)|mint:O60664|reactome:R-HSA-163560|reactome:R-HSA-6811440|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9706019|panther:PTHR14024(orthology-group)"	interpro:IPR027417|refseq:WP_002215686.1|interpro:IPR033186|refseq:YP_002345254.1|interpro:IPR051162|panther:PTHR30121(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:U+skqZ/oQtQscaEvfdh+AVnCCKA9606	rogid:7T8Io5VjMpoAGWF393x9GYtAK2w632	intact-crc:4364B93F3DEDC0F1|rigid:IB4uzqZ8lhEqbeJUOiR1XNhIufk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBN6	uniprotkb:Q6ZN16	intact:EBI-2845174|uniprotkb:Q0WBS4|uniprotkb:Q8D198|uniprotkb:Q74XS5	intact:EBI-2865050|uniprotkb:Q6ZMV3|uniprotkb:A2AI50|uniprotkb:Q5JPR4|uniprotkb:A6NJ61|uniprotkb:A2AI49|ensembl:ENSP00000345629.4	psi-mi:cysj_yerpe(display_long)|uniprotkb:cysJ(gene name)|psi-mi:cysJ(display_short)|uniprotkb:YPO3372(locus name)|uniprotkb:y0818(locus name)|uniprotkb:YP_0314(locus name)	psi-mi:m3k15_human(display_long)|uniprotkb:MAP3K15(gene name)|psi-mi:MAP3K15(display_short)|uniprotkb:ASK3(gene name synonym)|uniprotkb:Apoptosis signal-regulating kinase 3(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase 15(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865047|imex:IM-13779-7055	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010199(Sulphite reductase [NADPH] flavoprotein, alpha chain)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR017927|interpro:IPR001094(Flavodoxin-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR017938|interpro:IPR039261|interpro:IPR029039|interpro:IPR029758|refseq:WP_002209381.1|go:""GO:0000103""(sulfate assimilation)|go:""GO:0004783""(""sulfite reductase (NADPH) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0010181""(FMN binding)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0019344""(cysteine biosynthetic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070814""(hydrogen sulfide biosynthetic process)|interpro:IPR023173|refseq:YP_002348264.1|panther:PTHR19384(orthology-group)"	"refseq:XP_011543813.1|refseq:NP_001001671.3|ensembl:ENSG00000180815.15(gene)|ensembl:ENST00000338883.9(transcript)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0007254""(JNK cascade)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0046872""(metal ion binding)|go:""GO:0106310""(protein serine kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025136|interpro:IPR043969|interpro:IPR046872|interpro:IPR046873|rcsb pdb:6V0M|panther:PTHR11584(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/eQRgxmu+tsNIMHFJ+J0UIYifNc632	rogid:8s8R8yiu4OKPfxnuLAeH48wi25c9606	intact-crc:4507BBD8CDE1198B|rigid:Fv3WOoQ5PG4YN+kZHyFQ/imI1sQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P07948	uniprotkb:A0A3G5L2D0	intact:EBI-79452|uniprotkb:A0AVQ5|intact:EBI-6868890|ensembl:ENSP00000428924.1	intact:EBI-2865067	psi-mi:lyn_human(display_long)|uniprotkb:JTK8(gene name synonym)|uniprotkb:Lck/Yes-related novel protein tyrosine kinase(gene name synonym)|uniprotkb:V-yes-1 Yamaguchi sarcoma viral related oncogene homolog(gene name synonym)|uniprotkb:p53Lyn(gene name synonym)|uniprotkb:p56Lyn(gene name synonym)|uniprotkb:LYN(gene name)|psi-mi:LYN(display_short)	psi-mi:a0a3g5l2d0_yerpe(display_long)|uniprotkb:dgoA1(gene name)|psi-mi:dgoA1(display_short)|uniprotkb:mdlA(gene name synonym)|uniprotkb:NCTC5923_01545(orf name)|uniprotkb:YP_1455(locus name)|uniprotkb:y2598(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865064|imex:IM-13779-7056	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001104567.1|refseq:NP_002341.1|panther:PTHR24418(orthology-group)|refseq:XP_016868905.1|dip:DIP-1056N|ensembl:ENSG00000254087.8(gene)|ensembl:ENST00000519728.6(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002431""(Fc receptor mediated stimulatory signaling pathway)|go:""GO:0002513""(tolerance induction to self antigen)|go:""GO:0002553""(histamine secretion by mast cell)|go:""GO:0002576""(platelet degranulation)|go:""GO:0002762""(negative regulation of myeloid leukocyte differentiation)|go:""GO:0002768""(immune response-regulating cell surface receptor signaling pathway)|go:""GO:0002774""(Fc receptor mediated inhibitory signaling pathway)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0002902""(regulation of B cell apoptotic process)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005161""(platelet-derived growth factor receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006914""(autophagy)|go:""GO:0006974""(DNA damage response)|go:""GO:0006991""(response to sterol depletion)|go:""GO:0007165""(signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009725""(response to hormone)|go:""GO:0009743""(response to carbohydrate)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0015908""(fatty acid transport)|go:""GO:0016301""(kinase activity)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030222""(eosinophil differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0031175""(neuron projection development)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032868""(response to insulin)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034136""(negative regulation of toll-like receptor 2 signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0034144""(negative regulation of toll-like receptor 4 signaling pathway)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0038043""(interleukin-5-mediated signaling pathway)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0038159""(C-X-C chemokine receptor CXCR4 signaling pathway)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0043208""(glycosphingolipid binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043304""(regulation of mast cell degranulation)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048678""(response to axon injury)|go:""GO:0050777""(negative regulation of immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050855""(regulation of B cell receptor signaling pathway)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060369""(positive regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070447""(positive regulation of oligodendrocyte progenitor proliferation)|go:""GO:0070667""(negative regulation of mast cell proliferation)|go:""GO:0070668""(positive regulation of mast cell proliferation)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0090025""(regulation of monocyte chemotaxis)|go:""GO:0090330""(regulation of platelet aggregation)|go:""GO:0097028""(dendritic cell differentiation)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099091""(postsynaptic specialization, intracellular component)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0141038""(phosphatidylinositol 3-kinase activator activity)|go:""GO:0150076""(neuroinflammatory response)|go:""GO:1902532""(negative regulation of intracellular signal transduction)|go:""GO:1902961""(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:""GO:2000670""(positive regulation of dendritic cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035748|interpro:IPR035852|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P07948|rcsb pdb:1W1F|rcsb pdb:1WA7|rcsb pdb:3A4O|rcsb pdb:5XY1|rcsb pdb:6NMW|rcsb pdb:8WFF|reactome:R-HSA-114604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2454202|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5690714|reactome:R-HSA-69231|reactome:R-HSA-75892|reactome:R-HSA-9006335|reactome:R-HSA-9027276|reactome:R-HSA-9027277|reactome:R-HSA-9027283|reactome:R-HSA-9027284|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983695"	"uniprotkb:A0A5P8YE18(uniprot-removed-ac)|interpro:IPR013341(Mandelate racemase/muconate lactonizing enzyme, N-terminal)|interpro:IPR013342(Mandelate racemase/muconate lactonizing enzyme, C-terminal)|interpro:IPR018110|interpro:IPR029017|interpro:IPR029065|interpro:IPR034610|interpro:IPR036849|go:""GO:0009063""(amino acid catabolic process)|go:""GO:0016052""(carbohydrate catabolic process)|go:""GO:0016853""(isomerase activity)|go:""GO:0050023""(L-fuconate dehydratase activity)|refseq:WP_002211917.1|interpro:IPR046945"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:SqXPSC+g2ZuGHy6TAPV4HcpXe6U9606	rogid:VVqXuBcpx8OVQX8Y9zSahq0fRvI632	intact-crc:7C87DC1BAA119A0C|rigid:e0cEFolTHD3r9EHyxfvaYdFdWJs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CJG3	uniprotkb:P07948	intact:EBI-2844548|uniprotkb:Q74SH9	intact:EBI-79452|uniprotkb:A0AVQ5|intact:EBI-6868890|ensembl:ENSP00000428924.1	psi-mi:macb2_yerpe(display_long)|uniprotkb:macB2(gene name)|psi-mi:macB2(display_short)|uniprotkb:YPO3000(locus name)|uniprotkb:y1480(locus name)|uniprotkb:YP_2625(locus name)	psi-mi:lyn_human(display_long)|uniprotkb:JTK8(gene name synonym)|uniprotkb:Lck/Yes-related novel protein tyrosine kinase(gene name synonym)|uniprotkb:V-yes-1 Yamaguchi sarcoma viral related oncogene homolog(gene name synonym)|uniprotkb:p53Lyn(gene name synonym)|uniprotkb:p56Lyn(gene name synonym)|uniprotkb:LYN(gene name)|psi-mi:LYN(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865076|imex:IM-13779-7058	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|interpro:IPR027417|refseq:WP_002208496.1|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0046677""(response to antibiotic)|refseq:YP_002347924.1|interpro:IPR050250|panther:PTHR30572(orthology-group)"	"refseq:NP_001104567.1|refseq:NP_002341.1|panther:PTHR24418(orthology-group)|refseq:XP_016868905.1|dip:DIP-1056N|ensembl:ENSG00000254087.8(gene)|ensembl:ENST00000519728.6(transcript)|go:""GO:0000077""(DNA damage checkpoint signaling)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001782""(B cell homeostasis)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002431""(Fc receptor mediated stimulatory signaling pathway)|go:""GO:0002513""(tolerance induction to self antigen)|go:""GO:0002553""(histamine secretion by mast cell)|go:""GO:0002576""(platelet degranulation)|go:""GO:0002762""(negative regulation of myeloid leukocyte differentiation)|go:""GO:0002768""(immune response-regulating cell surface receptor signaling pathway)|go:""GO:0002774""(Fc receptor mediated inhibitory signaling pathway)|go:""GO:0002862""(negative regulation of inflammatory response to antigenic stimulus)|go:""GO:0002902""(regulation of B cell apoptotic process)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005161""(platelet-derived growth factor receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006914""(autophagy)|go:""GO:0006974""(DNA damage response)|go:""GO:0006991""(response to sterol depletion)|go:""GO:0007165""(signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009725""(response to hormone)|go:""GO:0009743""(response to carbohydrate)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0015908""(fatty acid transport)|go:""GO:0016301""(kinase activity)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030061""(mitochondrial crista)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030222""(eosinophil differentiation)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0031175""(neuron projection development)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032868""(response to insulin)|go:""GO:0033003""(regulation of mast cell activation)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034136""(negative regulation of toll-like receptor 2 signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0034144""(negative regulation of toll-like receptor 4 signaling pathway)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0038043""(interleukin-5-mediated signaling pathway)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0038096""(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:""GO:0038159""(C-X-C chemokine receptor CXCR4 signaling pathway)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0043208""(glycosphingolipid binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043304""(regulation of mast cell degranulation)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0045646""(regulation of erythrocyte differentiation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048678""(response to axon injury)|go:""GO:0050777""(negative regulation of immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050855""(regulation of B cell receptor signaling pathway)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060369""(positive regulation of Fc receptor mediated stimulatory signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070447""(positive regulation of oligodendrocyte progenitor proliferation)|go:""GO:0070667""(negative regulation of mast cell proliferation)|go:""GO:0070668""(positive regulation of mast cell proliferation)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0090025""(regulation of monocyte chemotaxis)|go:""GO:0090330""(regulation of platelet aggregation)|go:""GO:0097028""(dendritic cell differentiation)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099091""(postsynaptic specialization, intracellular component)|go:""GO:0140031""(phosphorylation-dependent protein binding)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0141038""(phosphatidylinositol 3-kinase activator activity)|go:""GO:0150076""(neuroinflammatory response)|go:""GO:1902532""(negative regulation of intracellular signal transduction)|go:""GO:1902961""(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:""GO:2000670""(positive regulation of dendritic cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035748|interpro:IPR035852|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P07948|rcsb pdb:1W1F|rcsb pdb:1WA7|rcsb pdb:3A4O|rcsb pdb:5XY1|rcsb pdb:6NMW|rcsb pdb:8WFF|reactome:R-HSA-114604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2454202|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5690714|reactome:R-HSA-69231|reactome:R-HSA-75892|reactome:R-HSA-9006335|reactome:R-HSA-9027276|reactome:R-HSA-9027277|reactome:R-HSA-9027283|reactome:R-HSA-9027284|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9674555|reactome:R-HSA-9680350|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983695"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:qWvpFRqsQF+xx75wAFlSYA197R0632	rogid:SqXPSC+g2ZuGHy6TAPV4HcpXe6U9606	intact-crc:E53D93C241A7D347|rigid:V5cKdWZ3r/OfiTWgdRWwi79FHBw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZDJ2	uniprotkb:Q86V48	intact:EBI-2844031|uniprotkb:Q0WDV6	intact:EBI-350467|uniprotkb:Q5TH93|uniprotkb:Q8N4X3|uniprotkb:Q8TEH1|ensembl:ENSP00000303758.4|ensembl:ENSP00000428061.2|ensembl:ENSP00000429657.2|ensembl:ENSP00000516586.2|ensembl:ENSP00000518969.1	psi-mi:a2mgh_yerpe(display_long)|uniprotkb:YPO2573(locus name)|uniprotkb:y1143(locus name)|uniprotkb:YP_1141(locus name)	psi-mi:luzp1_human(display_long)|uniprotkb:LUZP1(gene name)|psi-mi:LUZP1(display_short)|uniprotkb:Filamin mechanobinding actin cross-linking protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865123|imex:IM-13779-7062	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021868|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|go:""GO:0004866""(endopeptidase inhibitor activity)|interpro:IPR041203|interpro:IPR041246|interpro:IPR041462|refseq:YP_002347532.1|interpro:IPR051802|panther:PTHR40094(orthology-group)"	"efo:""Orphanet:1606""|ensembl:ENSG00000169641.16(gene)|ensembl:ENST00000302291.9(transcript)|ensembl:ENST00000471849.6(transcript)|ensembl:ENST00000475164.3(transcript)|ensembl:ENST00000706844.2(transcript)|ensembl:ENST00000713666.1(transcript)|go:""GO:0000775""(chromosome, centromeric region)|go:""GO:0001725""(stress fiber)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003383""(apical constriction)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005884""(actin filament)|go:""GO:0008017""(microtubule binding)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0021503""(neural fold bending)|go:""GO:0030496""(midbody)|go:""GO:0036064""(ciliary basal body)|go:""GO:0036213""(contractile ring contraction)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0051015""(actin filament binding)|go:""GO:0051233""(spindle midzone)|go:""GO:0060840""(artery development)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070160""(tight junction)|go:""GO:0090537""(CERF complex)|go:""GO:1902018""(negative regulation of cilium assembly)|go:""GO:1903119""(protein localization to actin cytoskeleton)|interpro:IPR050719|mint:Q86V48|refseq:NP_001136018.1|refseq:NP_361013.3|refseq:XP_011540392.1|refseq:XP_011540393.1|refseq:XP_016857741.1|dip:DIP-33113N|panther:PTHR23166(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9FN1refl1me6jgo6ehCPO8MzV8Y632	rogid:l456S0i3H1z5fv6M4SNkdrls/c49606	intact-crc:61346ED7E45CFF80|rigid:XGVQHaO+gL9dRrUkb3FIDqAm6Cw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13342	uniprotkb:Q8CZQ3	intact:EBI-2865100|uniprotkb:Q92881|uniprotkb:Q13341|uniprotkb:Q4ZG66|uniprotkb:Q96TG3|uniprotkb:Q53TG1|uniprotkb:Q6NSG4|uniprotkb:E7ESH9|uniprotkb:E7EUR5|uniprotkb:E9PFJ6|uniprotkb:Q0VGE5|uniprotkb:Q3KR17|ensembl:ENSP00000375899.3|intact:EBI-28968654	intact:EBI-2849368|uniprotkb:Q74Q61	psi-mi:sp140_human(display_long)|uniprotkb:SP140(gene name)|psi-mi:SP140(display_short)|uniprotkb:LYSP100(gene name synonym)|uniprotkb:Lymphoid-restricted homolog of Sp100(gene name synonym)|uniprotkb:Nuclear autoantigen Sp-140(gene name synonym)|uniprotkb:Speckled 140 kDa(gene name synonym)	psi-mi:q8czq3_yerpe(display_long)|uniprotkb:ilvI(gene name)|psi-mi:ilvI(display_short)|uniprotkb:y3640(locus name)|uniprotkb:YP_3646(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865116|imex:IM-13779-7060	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009168.4|refseq:NP_001005176.1|refseq:NP_001265380.1|refseq:NP_001265381.1|refseq:NP_001265382.1|ensembl:ENSG00000079263.19(gene)|ensembl:ENST00000392045.8(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001650""(fibrillar center)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006952""(defense response)|go:""GO:0016605""(PML body)|go:""GO:0046872""(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR030411|interpro:IPR036427|interpro:IPR043563|mint:Q13342|rcsb pdb:2MD7|rcsb pdb:2MD8|rcsb pdb:6G8R|rcsb pdb:8J70|rcsb pdb:8J71|panther:PTHR46386(orthology-group)"	"interpro:IPR039368|interpro:IPR012846(Acetolactate synthase, large subunit, biosynthetic)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR029035|interpro:IPR029061|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003984""(acetolactate synthase activity)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR045229"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MVL7OomlAVjWAq+SNyAXudqCLyc9606	rogid:HjawDXJtJf287797Q9KXxlU93ng632	intact-crc:97FD3CACE70D1473|rigid:3x5JWCvR90/TZ31FH537ZbuBjVY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13342	uniprotkb:Q0WBF9	intact:EBI-2865100|uniprotkb:Q92881|uniprotkb:Q13341|uniprotkb:Q4ZG66|uniprotkb:Q96TG3|uniprotkb:Q53TG1|uniprotkb:Q6NSG4|uniprotkb:E7ESH9|uniprotkb:E7EUR5|uniprotkb:E9PFJ6|uniprotkb:Q0VGE5|uniprotkb:Q3KR17|ensembl:ENSP00000375899.3|intact:EBI-28968654	intact:EBI-2856682|uniprotkb:Q74X66|uniprotkb:Q8D1D1	psi-mi:sp140_human(display_long)|uniprotkb:SP140(gene name)|psi-mi:SP140(display_short)|uniprotkb:LYSP100(gene name synonym)|uniprotkb:Lymphoid-restricted homolog of Sp100(gene name synonym)|uniprotkb:Nuclear autoantigen Sp-140(gene name synonym)|uniprotkb:Speckled 140 kDa(gene name synonym)	psi-mi:pnp_yerpe(display_long)|uniprotkb:pnp(gene name)|psi-mi:pnp(display_short)|uniprotkb:Polynucleotide phosphorylase(gene name synonym)|uniprotkb:YPO3490(locus name)|uniprotkb:y0694(locus name)|uniprotkb:YP_0593(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865109|imex:IM-13779-7059	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009168.4|refseq:NP_001005176.1|refseq:NP_001265380.1|refseq:NP_001265381.1|refseq:NP_001265382.1|ensembl:ENSG00000079263.19(gene)|ensembl:ENST00000392045.8(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001650""(fibrillar center)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006952""(defense response)|go:""GO:0016605""(PML body)|go:""GO:0046872""(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR030411|interpro:IPR036427|interpro:IPR043563|mint:Q13342|rcsb pdb:2MD7|rcsb pdb:2MD8|rcsb pdb:6G8R|rcsb pdb:8J70|rcsb pdb:8J71|panther:PTHR46386(orthology-group)"	"refseq:WP_002209259.1|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR020568|interpro:IPR027408|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004654""(polyribonucleotide nucleotidyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0006401""(RNA catabolic process)|go:""GO:0006402""(mRNA catabolic process)|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612|refseq:YP_002348379.1|panther:PTHR11252(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MVL7OomlAVjWAq+SNyAXudqCLyc9606	rogid:OtyeeLgdrKybDBd4sPZ7s/ufy78632	intact-crc:AE2E80936D574F6D|rigid:IZLyZlGr2Q1kLBE1WCvxuYnBxm0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60449	uniprotkb:Q8CWG5	intact:EBI-2865083|uniprotkb:Q7Z575|uniprotkb:Q7Z577|uniprotkb:Q53R46|uniprotkb:Q53TF5|uniprotkb:O75913|ensembl:ENSP00000263636.4	intact:EBI-2844481|uniprotkb:Q74YC5	psi-mi:ly75_human(display_long)|uniprotkb:LY75(gene name)|psi-mi:LY75(display_short)|uniprotkb:CD205(gene name synonym)|uniprotkb:CLEC13B(gene name synonym)|uniprotkb:C-type lectin domain family 13 member B(gene name synonym)|uniprotkb:DEC-205(gene name synonym)|uniprotkb:gp200-MR6(gene name synonym)	"psi-mi:q8cwg5_yerpe(display_long)|uniprotkb:glnG(gene name)|psi-mi:glnG(display_short)|uniprotkb:ntrC(gene name synonym)|uniprotkb:YP_0023(locus name)|uniprotkb:y3806(locus name)|uniprotkb:""Nitrogen regulation protein NR(I)""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865093|imex:IM-13779-7061	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001185688.1|refseq:NP_001185689.1|refseq:NP_002340.2|ensembl:ENSG00000054219.11(gene)|ensembl:ENST00000263636.5(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001304(C-type lectin)|interpro:IPR013806(Kringle-like fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR035992|interpro:IPR036943|interpro:IPR050111|rcsb pdb:7JPT|rcsb pdb:7JPU|rcsb pdb:8HBC|rcsb pdb:8K8H|panther:PTHR22803(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR010114(""Signal transduction response regulator, nitrogen regulation NR(I)"")|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|interpro:IPR027417|go:""GO:0000156""(phosphorelay response regulator activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006808""(regulation of nitrogen utilization)|go:""GO:0009399""(nitrogen fixation)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0043565""(sequence-specific DNA binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1mLl2nKn1pGKEDDQzCjBLgVcZ5c9606	rogid:+KTzls70+B2JgZKs1QJMXp3JzcU632	intact-crc:AB176A1988432896|rigid:afwW2xwSTplgXAPRokPv4ZSsS/c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N2S1	uniprotkb:Q8ZJC5	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905.8	intact:EBI-2865161|uniprotkb:Q0WKB6	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	psi-mi:kefg_yerpe(display_long)|uniprotkb:kefG(gene name)|psi-mi:kefG(display_short)|uniprotkb:Putative quinone oxidoreductase KefG(gene name synonym)|uniprotkb:YPO0190(locus name)|uniprotkb:YP_0188(locus name)|uniprotkb:y3971(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865158|imex:IM-13779-7065	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090006.18(gene)|ensembl:ENST00000308370.11(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006457""(protein folding)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031012""(extracellular matrix)|go:""GO:0046879""(hormone secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q8N2S1|reactome:R-HSA-2129379|reactome:R-HSA-2173789|refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|efo:""Orphanet:221145""|efo:""Orphanet:98896""|panther:PTHR24034(orthology-group)"	"interpro:IPR003680(Flavodoxin-like fold)|interpro:IPR023947|interpro:IPR029039|go:""GO:0003955""(""NAD(P)H dehydrogenase (quinone) activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0006813""(potassium ion transport)|go:""GO:0008753""(""NADPH dehydrogenase (quinone) activity"")|go:""GO:0009055""(electron transfer activity)|go:""GO:0010181""(FMN binding)|go:""GO:0050136""(""NADH:ubiquinone reductase (non-electrogenic) activity"")|go:""GO:1901381""(positive regulation of potassium ion transmembrane transport)|refseq:YP_002345272.1|interpro:IPR046980|panther:PTHR47307(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	rogid:76OyXCYEo2ovqcJldq1Qj/On5CY632	intact-crc:4E35AAD338402151|rigid:UrIBwaDko88voIAkvrPFZMlIlAs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GV98	uniprotkb:Q9NQ29	intact:EBI-2842935|uniprotkb:Q0WA52|uniprotkb:Q7CG01|uniprotkb:A0A380PFZ4|uniprotkb:A0A384KIG3	intact:EBI-473747|uniprotkb:Q96S32|uniprotkb:Q9NPH4|uniprotkb:B8ZZ13|ensembl:ENSP00000293872.8	psi-mi:a0a2u2gv98_yerpe(display_long)|uniprotkb:YPO3965(locus name)	psi-mi:luc7l_human(display_long)|uniprotkb:SR+89(gene name synonym)|uniprotkb:Putative SR protein LUC7B1(gene name synonym)|uniprotkb:LUC7L(gene name)|psi-mi:LUC7L(display_short)|uniprotkb:LUC7L1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865130|imex:IM-13779-7067	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR000014(PAS)|interpro:IPR005467(Signal transduction histidine kinase, core)|refseq:WP_002209524.1|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0016020""(membrane)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|refseq:YP_002348836.1"	"refseq:NP_001307155.1|refseq:NP_001317349.1|refseq:NP_060502.1|refseq:NP_958815.1|panther:PTHR12375(orthology-group)|ensembl:ENSG00000007392.17(gene)|ensembl:ENST00000293872.13(transcript)|go:""GO:0003729""(mRNA binding)|go:""GO:0005685""(U1 snRNP)|go:""GO:0006376""(mRNA splice site recognition)|go:""GO:0042802""(identical protein binding)|go:""GO:0045843""(negative regulation of striated muscle tissue development)|go:""GO:0050733""(RS domain binding)|go:""GO:0071004""(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9NQ29"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l6f5EnoNPBCpn3IKEDOJAOvm7+w632	rogid:Hsl0VZTCTP6UrKlo/FHOVwZqCaw9606	intact-crc:1B83E31622A739E0|rigid:lVXjR9kU+fYIc1Refp9jrtg2UA0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N2S1	uniprotkb:Q8Z9U2	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905.8	intact:EBI-2843724|uniprotkb:Q0W9T4	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	psi-mi:mnme_yerpe(display_long)|uniprotkb:mnmE(gene name)|psi-mi:mnmE(display_short)|uniprotkb:thdF(gene name synonym)|uniprotkb:trmE(gene name synonym)|uniprotkb:YPO4103(locus name)|uniprotkb:y4118(locus name)|uniprotkb:YP_4010(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865137|imex:IM-13779-7063	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090006.18(gene)|ensembl:ENST00000308370.11(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006457""(protein folding)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031012""(extracellular matrix)|go:""GO:0046879""(hormone secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q8N2S1|reactome:R-HSA-2129379|reactome:R-HSA-2173789|refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|efo:""Orphanet:221145""|efo:""Orphanet:98896""|panther:PTHR24034(orthology-group)"	"interpro:IPR018948|interpro:IPR004520(tRNA modification GTPase TrmE)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR025867|interpro:IPR027417|interpro:IPR031168|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0046872""(metal ion binding)|interpro:IPR027266|interpro:IPR027368|refseq:YP_002348954.1|panther:PTHR42714(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	rogid:XaI2j4tZS0U65rUmSnAsXuaqAKo632	intact-crc:DAEF69D339D2CADE|rigid:+3CMd2JC5231M3S8DJM5vbI2UeY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N2S1	uniprotkb:A0A2U2H1T2	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905.8	intact:EBI-2847930|uniprotkb:A0A380PGD9|uniprotkb:Q0WBW0|uniprotkb:Q7CKB2|uniprotkb:A0A384KAJ5	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	psi-mi:a0a2u2h1t2_yerpe(display_long)|uniprotkb:YPO3332(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865144|imex:IM-13779-7066	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090006.18(gene)|ensembl:ENST00000308370.11(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006457""(protein folding)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031012""(extracellular matrix)|go:""GO:0046879""(hormone secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q8N2S1|reactome:R-HSA-2129379|reactome:R-HSA-2173789|refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|efo:""Orphanet:221145""|efo:""Orphanet:98896""|panther:PTHR24034(orthology-group)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|refseq:WP_002216010.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:YP_002348228.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	rogid:pJcJoiSi0mBqBQjt8m5FB8UHoDE632	intact-crc:91C3BDD617FDDD1F|rigid:zS4ydTBPWWagjp/TUDjuP5lwl6Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCW0	uniprotkb:Q8N2S1	intact:EBI-2842923|uniprotkb:Q7CJK9|uniprotkb:Q0WD52|uniprotkb:Q74SA7	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905.8	psi-mi:mdtb_yerpe(display_long)|uniprotkb:mdtB(gene name)|psi-mi:mdtB(display_short)|uniprotkb:Multidrug transporter MdtB(gene name synonym)|uniprotkb:YPO2848(locus name)|uniprotkb:y1385(locus name)|uniprotkb:YP_2715(locus name)	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865151|imex:IM-13779-7064	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR022831|interpro:IPR027463|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:WP_002209793.1|refseq:YP_002347786.1|panther:PTHR32063(orthology-group)"	"ensembl:ENSG00000090006.18(gene)|ensembl:ENST00000308370.11(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006457""(protein folding)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031012""(extracellular matrix)|go:""GO:0046879""(hormone secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q8N2S1|reactome:R-HSA-2129379|reactome:R-HSA-2173789|refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|efo:""Orphanet:221145""|efo:""Orphanet:98896""|panther:PTHR24034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LHw1WKWrAW5/xlsQ5C6WVb5Ua3M632	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	intact-crc:FFD753D3396B9D7C|rigid:ogUIhFJ60zWV79lpHZUazVKB1OI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q07954	uniprotkb:A0A0H2W6E9	intact:EBI-1046087|uniprotkb:Q8IVG8|uniprotkb:Q2PP12|uniprotkb:Q86SW0|ensembl:ENSP00000243077.3	intact:EBI-2853427|uniprotkb:Q74WL2|uniprotkb:Q74XZ4|uniprotkb:Q74WU0|uniprotkb:Q8CLY1	psi-mi:lrp1_human(display_long)|uniprotkb:Alpha-2-macroglobulin receptor(gene name synonym)|uniprotkb:Apolipoprotein E receptor(gene name synonym)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:A2MR(gene name synonym)|uniprotkb:APR(gene name synonym)	psi-mi:a0a0h2w6e9_yerpe(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865184|imex:IM-13779-7069	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50613N|efo:""Orphanet:2340""|efo:""Orphanet:79100""|ensembl:ENSG00000123384.14(gene)|ensembl:ENST00000243077.8(transcript)|go:""GO:0001523""(retinoid metabolic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0005041""(low-density lipoprotein particle receptor activity)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005925""(focal adhesion)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006909""(phagocytosis)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007167""(enzyme-linked receptor protein signaling pathway)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010715""(regulation of extracellular matrix disassembly)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0014912""(negative regulation of smooth muscle cell migration)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016964""(alpha-2 macroglobulin receptor activity)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030226""(apolipoprotein receptor activity)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0032050""(clathrin heavy chain binding)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032370""(positive regulation of lipid transport)|go:""GO:0032374""(regulation of cholesterol transport)|go:""GO:0032429""(regulation of phospholipase A2 activity)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0035909""(aorta morphogenesis)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0043235""(receptor complex)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045056""(transcytosis)|go:""GO:0045807""(positive regulation of endocytosis)|go:""GO:0060392""(negative regulation of SMAD protein signal transduction)|go:""GO:0070325""(lipoprotein particle receptor binding)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:0150094""(amyloid-beta clearance by cellular catabolic process)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1900223""(positive regulation of amyloid-beta clearance)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1904300""(positive regulation of transcytosis)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905049""(negative regulation of metallopeptidase activity)|go:""GO:1905167""(positive regulation of lysosomal protein catabolic process)|go:""GO:2000587""(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR032485|interpro:IPR036055|interpro:IPR049883|interpro:IPR051221|mint:Q07954|rcsb pdb:1CR8|rcsb pdb:1D2L|rcsb pdb:1J8E|rcsb pdb:2FYJ|rcsb pdb:2FYL|rcsb pdb:2KNX|rcsb pdb:2KNY|reactome:R-HSA-2168880|reactome:R-HSA-975634|refseq:NP_002323.2|panther:PTHR24270(orthology-group)"	"refseq:YP_093918.1|interpro:IPR002686(Transposase IS200-like)|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|interpro:IPR036515"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:eO2l3huuq6NYoVoYdoCloLqrlRw9606	rogid:7GOftNTJxtzq5aUbatG8ug5sIa0632	intact-crc:30E690CB7DBDCAEF|rigid:UZzawf8EzTL+1bz9kBPI3w/M/sY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75427	uniprotkb:A0A2U2GUX9	intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689.6	intact:EBI-2841416|uniprotkb:A0A0H2W940|uniprotkb:Q74PB0|uniprotkb:A0A384LLI5|uniprotkb:Q7CFN3|uniprotkb:A0A3N4BJ32	psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym)	psi-mi:a0a2u2gux9_yerpe(display_long)|uniprotkb:YPO4108(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865207|imex:IM-13779-7072	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002310.2|ensembl:ENSG00000077454.17(gene)|ensembl:ENST00000310300.11(transcript)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0007399""(nervous system development)|go:""GO:0016605""(PML body)|go:""GO:0034123""(positive regulation of toll-like receptor signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872|interpro:IPR050216|mint:O75427|refseq:NP_001276863.1|panther:PTHR16083(orthology-group)"	"interpro:IPR023214|interpro:IPR041492|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002215575.1|refseq:YP_002348959.1|interpro:IPR023198|interpro:IPR036412|interpro:IPR051600"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606	rogid:N4DmZVhdbeJX1EvnC462dwFiaNU632	intact-crc:283C475847C5806E|rigid:oqLyKowG80NEC17CNlSzhbaWg90	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZY7	uniprotkb:Q07954	intact:EBI-2842279|uniprotkb:Q0WI10|uniprotkb:Q8ZH74	intact:EBI-1046087|uniprotkb:Q8IVG8|uniprotkb:Q2PP12|uniprotkb:Q86SW0|ensembl:ENSP00000243077.3	psi-mi:sydp_yerpe(display_long)|uniprotkb:syd(gene name)|psi-mi:syd(display_short)|uniprotkb:YPO1035(locus name)|uniprotkb:y3146(locus name)|uniprotkb:YP_2816(locus name)	psi-mi:lrp1_human(display_long)|uniprotkb:Alpha-2-macroglobulin receptor(gene name synonym)|uniprotkb:Apolipoprotein E receptor(gene name synonym)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:A2MR(gene name synonym)|uniprotkb:APR(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865177|imex:IM-13779-7071	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009948(Syd)|interpro:IPR038228|go:""GO:0009898""(cytoplasmic side of plasma membrane)|refseq:WP_002212123.1|refseq:YP_002346078.1"	"dip:DIP-50613N|efo:""Orphanet:2340""|efo:""Orphanet:79100""|ensembl:ENSG00000123384.14(gene)|ensembl:ENST00000243077.8(transcript)|go:""GO:0001523""(retinoid metabolic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0005041""(low-density lipoprotein particle receptor activity)|go:""GO:0005044""(scavenger receptor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0005925""(focal adhesion)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006909""(phagocytosis)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007167""(enzyme-linked receptor protein signaling pathway)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010715""(regulation of extracellular matrix disassembly)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0014912""(negative regulation of smooth muscle cell migration)|go:""GO:0016020""(membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016964""(alpha-2 macroglobulin receptor activity)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030226""(apolipoprotein receptor activity)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0031623""(receptor internalization)|go:""GO:0032050""(clathrin heavy chain binding)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032370""(positive regulation of lipid transport)|go:""GO:0032374""(regulation of cholesterol transport)|go:""GO:0032429""(regulation of phospholipase A2 activity)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0035909""(aorta morphogenesis)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0038024""(cargo receptor activity)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0043235""(receptor complex)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0043395""(heparan sulfate proteoglycan binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045056""(transcytosis)|go:""GO:0045807""(positive regulation of endocytosis)|go:""GO:0060392""(negative regulation of SMAD protein signal transduction)|go:""GO:0070325""(lipoprotein particle receptor binding)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:0150093""(amyloid-beta clearance by transcytosis)|go:""GO:0150094""(amyloid-beta clearance by cellular catabolic process)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1900223""(positive regulation of amyloid-beta clearance)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1904300""(positive regulation of transcytosis)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1905049""(negative regulation of metallopeptidase activity)|go:""GO:1905167""(positive regulation of lysosomal protein catabolic process)|go:""GO:2000587""(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR032485|interpro:IPR036055|interpro:IPR049883|interpro:IPR051221|mint:Q07954|rcsb pdb:1CR8|rcsb pdb:1D2L|rcsb pdb:1J8E|rcsb pdb:2FYJ|rcsb pdb:2FYL|rcsb pdb:2KNX|rcsb pdb:2KNY|reactome:R-HSA-2168880|reactome:R-HSA-975634|refseq:NP_002323.2|panther:PTHR24270(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:MC0GRav9hd62E9fkiCF0MQ5eBt4632	rogid:eO2l3huuq6NYoVoYdoCloLqrlRw9606	intact-crc:C51097885D0B07B4|rigid:os0RhVIFbzJMI9EU5zeXOg7k1fY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y608	uniprotkb:Q8ZGA1	intact:EBI-1023718|uniprotkb:Q68CV3|uniprotkb:Q9NXH5|uniprotkb:A8K649|uniprotkb:A8MXR0|uniprotkb:B4DY63|ensembl:ENSP00000338727.4	intact:EBI-2840375|uniprotkb:Q0WH12	psi-mi:lrrf2_human(display_long)|uniprotkb:LRRFIP2(gene name)|psi-mi:LRRFIP2(display_short)	psi-mi:mukf_yerpe(display_long)|uniprotkb:mukF(gene name)|psi-mi:mukF(display_short)|uniprotkb:YPO1403(locus name)|uniprotkb:y2767(locus name)|uniprotkb:YP_1190(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865170|imex:IM-13779-7068	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011532519.1|refseq:XP_011532520.1|refseq:XP_011532521.1|refseq:XP_005265596.1|refseq:XP_005265597.1|refseq:NP_001335239.1|refseq:NP_001335240.1|refseq:NP_006300.1|refseq:NP_060194.1|refseq:NP_001127841.1|refseq:NP_001269620.1|refseq:XP_016862973.1|ensembl:ENSG00000093167.18(gene)|ensembl:ENST00000336686.9(transcript)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030275""(LRR domain binding)|interpro:IPR019139|mint:Q9Y608|panther:PTHR19212(orthology-group)"	"interpro:IPR005582(Prokaryotic chromosome segregation and condensation protein MukF)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR033439|interpro:IPR033440|interpro:IPR033441|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0009295""(nucleoid)|go:""GO:0030261""(chromosome condensation)|go:""GO:0051301""(cell division)|interpro:IPR038198|refseq:YP_002346426.1|interpro:IPR036141|interpro:IPR036388|interpro:IPR036390|refseq:WP_002211310.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ma/crL7UY91uJ8bqLfkX3K8aQLI9606	rogid:zjd/0fYjzAPC90vlVgkjLwwGap0632	intact-crc:FBAD7FE4D31FA658|rigid:/g9CWD9nDcpro0KrvrdSZR+SucQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D097	uniprotkb:Q96JA1	intact:EBI-2849686	intact:EBI-2865191|uniprotkb:Q9BYB8|uniprotkb:Q96CF9|uniprotkb:Q6IQ51|uniprotkb:Q9UFI4|ensembl:ENSP00000273261.3	psi-mi:q8d097_yerpe(display_long)|uniprotkb:ptrB(gene name)|psi-mi:ptrB(display_short)|uniprotkb:y2527(locus name)	psi-mi:lrig1_human(display_long)|uniprotkb:LRIG1(gene name)|psi-mi:LRIG1(display_short)|uniprotkb:LIG1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865200|imex:IM-13779-7070	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023302|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002470(Peptidase S9A, prolyl oligopeptidase)|interpro:IPR029058|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:WP_002231190.1|interpro:IPR051543"	"refseq:NP_056356.2|ensembl:ENSG00000144749.14(gene)|ensembl:ENST00000273261.8(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0022405""(hair cycle process)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032474""(otolith morphogenesis)|go:""GO:0060384""(innervation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036179|interpro:IPR050467|rcsb pdb:4U7L|rcsb pdb:4U7M|reactome:R-HSA-177929|reactome:R-HSA-6807004|reactome:R-HSA-9725554|panther:PTHR24373(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:e1PUtAFibeLqTuVlv0AfdoPCzZQ632	rogid:bnp2t5D9UqLg2EqOUJg6P6BVaE09606	intact-crc:5A18445BF30C345D|rigid:zHeENDG0U/ZCTTy1agEn3atlgj0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBT8	uniprotkb:O60711	intact:EBI-2865235|uniprotkb:Q0WBY7	intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512.2	psi-mi:sya_yerpe(display_long)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO3305(locus name)|uniprotkb:YP_0381(locus name)|uniprotkb:y0883(locus name)|uniprotkb:alaS(gene name)|psi-mi:alaS(display_short)	psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865240|imex:IM-13779-7074	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR018162|interpro:IPR018165|interpro:IPR018164|interpro:IPR023033|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|refseq:WP_002209448.1|interpro:IPR050058|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004813""(alanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006419""(alanyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002348201.1|interpro:IPR045864|panther:PTHR11777(orthology-group)"	"refseq:NP_001137467.1|refseq:NP_004802.1|refseq:NP_001294880.1|ensembl:ENSG00000110031.13(gene)|ensembl:ENST00000395074.7(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042995""(cell projection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|panther:PTHR24216(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5ej2gX3V4h1hXP1LraN4GI1vT3w632	rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606	intact-crc:3B7E0D56D6F97839|rigid:/cggtW9kdh/FHyrfUG97/YKcjfg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50851	uniprotkb:Q0WBF9	intact:EBI-1052167|uniprotkb:Q9H2U3|uniprotkb:Q9H2U4|uniprotkb:Q8NFQ0|uniprotkb:Q4W5J4|uniprotkb:Q4W5L6|ensembl:ENSP00000349629.3	intact:EBI-2856682|uniprotkb:Q74X66|uniprotkb:Q8D1D1	psi-mi:lrba_human(display_long)|uniprotkb:CDC4-like protein(gene name synonym)|uniprotkb:Beige-like protein(gene name synonym)|uniprotkb:LRBA(gene name)|psi-mi:LRBA(display_short)|uniprotkb:BGL(gene name synonym)|uniprotkb:CDC4L(gene name synonym)|uniprotkb:LBA(gene name synonym)	psi-mi:pnp_yerpe(display_long)|uniprotkb:pnp(gene name)|psi-mi:pnp(display_short)|uniprotkb:Polynucleotide phosphorylase(gene name synonym)|uniprotkb:YPO3490(locus name)|uniprotkb:y0694(locus name)|uniprotkb:YP_0593(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865228|imex:IM-13779-7076	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-50531N|ensembl:ENSG00000198589.15(gene)|ensembl:ENST00000357115.9(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008104""(protein localization)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0034497""(protein localization to phagophore assembly site)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR010508(Protein of unknown function DUF1088)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|interpro:IPR046851|interpro:IPR046852|interpro:IPR050865|mint:P50851|rcsb pdb:1T77|refseq:NP_001186211.2|refseq:NP_006717.2|refseq:XP_011530736.1|efo:""Orphanet:445018""|panther:PTHR13743(orthology-group)"	"refseq:WP_002209259.1|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR020568|interpro:IPR027408|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004654""(polyribonucleotide nucleotidyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0006401""(RNA catabolic process)|go:""GO:0006402""(mRNA catabolic process)|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612|refseq:YP_002348379.1|panther:PTHR11252(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:FSUTaFKy63UUratp7X29LN/f1F49606	rogid:OtyeeLgdrKybDBd4sPZ7s/ufy78632	intact-crc:DAA55DAED98B7D74|rigid:VNv9opVgldmisypuQ9YpmqO9q2g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YMM0	uniprotkb:Q96CN5	intact:EBI-2844994|uniprotkb:Q74PA7|uniprotkb:Q7CFN1|uniprotkb:A0A0H2W8G4	intact:EBI-2805176|ensembl:ENSP00000306760.3	psi-mi:a0a5p8ymm0_yerpe(display_long)|uniprotkb:YPO4111(locus name)	psi-mi:lrc45_human(display_long)|uniprotkb:LRRC45(gene name)|psi-mi:LRRC45(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865221|imex:IM-13779-7073	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR018313|go:""GO:0005576""(extracellular region)|go:""GO:0006865""(amino acid transport)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:WP_002215568.1|refseq:YP_002348962.1|interpro:IPR051455|panther:PTHR30085(orthology-group)"	"refseq:NP_659436.1|ensembl:ENSG00000169683.8(gene)|ensembl:ENST00000306688.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR052116|mint:Q96CN5|dip:DIP-29482N|panther:PTHR23170(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	crc64:27F5D210721459FB	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:/TF3wEkKv/JvJMW7WimwR6S7ryU632	rogid:cuIAlpH4zLJ1La+TtOc2x4c2dMI9606	intact-crc:77921A8F97476971|rigid:44kLTOLchdZfNs4OtRDzYImlkic	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75427	uniprotkb:Q8ZAA1	intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689.6	intact:EBI-2860122|uniprotkb:Q74RC5|uniprotkb:Q8D1L7|uniprotkb:Q0WAA3	psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym)	psi-mi:btub_yerpe(display_long)|uniprotkb:btuB(gene name)|psi-mi:btuB(display_short)|uniprotkb:Cobalamin receptor(gene name synonym)|uniprotkb:Outer membrane cobalamin translocator(gene name synonym)|uniprotkb:YPO3910(locus name)|uniprotkb:y0325(locus name)|uniprotkb:YP_3138(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865214|imex:IM-13779-7077	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002310.2|ensembl:ENSG00000077454.17(gene)|ensembl:ENST00000310300.11(transcript)|go:""GO:0001765""(membrane raft assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0007399""(nervous system development)|go:""GO:0016605""(PML body)|go:""GO:0034123""(positive regulation of toll-like receptor signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872|interpro:IPR050216|mint:O75427|refseq:NP_001276863.1|panther:PTHR16083(orthology-group)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010101(TonB-dependent vitamin B12 receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR039426|go:""GO:0006811""(monoatomic ion transport)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0015420""(ABC-type vitamin B12 transporter activity)|go:""GO:0015889""(cobalamin transport)|go:""GO:0046872""(metal ion binding)|go:""GO:0046930""(pore complex)|interpro:IPR036942|interpro:IPR037066|refseq:WP_002228170.1|panther:PTHR30069(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606	rogid:DOy5Ti+yMtG0ogW80Av35K2fKW0632	intact-crc:08652F722F61CB86|rigid:SCiFkNMAoboQxBikVsWkCaWlNwc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0I3	uniprotkb:O60711	intact:EBI-2860455	intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512.2	psi-mi:q8d0i3_yerpe(display_long)|uniprotkb:manA(gene name)|psi-mi:manA(display_short)|uniprotkb:Phosphohexomutase(gene name synonym)|uniprotkb:Phosphomannose isomerase(gene name synonym)|uniprotkb:y2105(locus name)	psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865247|imex:IM-13779-7075	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR001250(Mannose-6-phosphate isomerase, type I)|interpro:IPR016305(Mannose-6-phosphate isomerase)|interpro:IPR018050|interpro:IPR014710(RmlC-like jelly roll fold)|go:""GO:0004476""(mannose-6-phosphate isomerase activity)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009298""(GDP-mannose biosynthetic process)|interpro:IPR049071|interpro:IPR046457|interpro:IPR046458"	"refseq:NP_001137467.1|refseq:NP_004802.1|refseq:NP_001294880.1|ensembl:ENSG00000110031.13(gene)|ensembl:ENST00000395074.7(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042995""(cell projection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|panther:PTHR24216(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wQlmh1sSD+u655e4iGuos8stS+0632	rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606	intact-crc:BE0B4CE8D4FD9738|rigid:mHqn+inRpw6j+i6/bofHwBmcZkE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60711	uniprotkb:Q8CZX0	intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512.2	intact:EBI-2843256	psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym)	psi-mi:q8czx0_yerpe(display_long)|uniprotkb:y3221(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865254|imex:IM-13779-7078	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001137467.1|refseq:NP_004802.1|refseq:NP_001294880.1|ensembl:ENSG00000110031.13(gene)|ensembl:ENST00000395074.7(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042995""(cell projection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|panther:PTHR24216(orthology-group)"	"interpro:IPR004704(Phosphotransferase system, mannose/fructose/sorbose family IID component)|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|interpro:IPR050303"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606	rogid:qJG/9uPdua0KpEAcJ9dXeyS7Cww632	intact-crc:915574BFD41D10DB|rigid:/OGL+IZKOMKHC4Rp7I39u4SNvEY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLR7	uniprotkb:O60711	intact:EBI-2844920|uniprotkb:Q74R33	intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512.2	psi-mi:q8clr7_yerpe(display_long)|uniprotkb:y0432(locus name)|uniprotkb:YP_3251(locus name)	psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865261|imex:IM-13779-7081	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR032636	"refseq:NP_001137467.1|refseq:NP_004802.1|refseq:NP_001294880.1|ensembl:ENSG00000110031.13(gene)|ensembl:ENST00000395074.7(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042995""(cell projection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|panther:PTHR24216(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LFM9kIM6yrsqDCleXMrQPlRyJlc632	rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606	intact-crc:582742BFD589B6B5|rigid:aicCvX0xphAOHSmwY0yChEBk4iw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Z381	uniprotkb:P42704	intact:EBI-2865275|uniprotkb:Q7CI37|uniprotkb:Q74UQ9|uniprotkb:A0A1U8QSX5|uniprotkb:A0A5P8YEH6|uniprotkb:A0A0H2W4A3	intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665.7	psi-mi:q9z381_yerpe(display_long)|uniprotkb:YPO1902(locus name)	psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865280|imex:IM-13779-7080	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR021364|refseq:WP_000937857.1|refseq:YP_002346892.1	"dip:DIP-27543N|ensembl:ENSG00000138095.20(gene)|ensembl:ENST00000260665.12(transcript)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000957""(mitochondrial RNA catabolic process)|go:""GO:0000961""(negative regulation of mitochondrial RNA catabolic process)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0006914""(autophagy)|go:""GO:0008017""(microtubule binding)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0051028""(mRNA transport)|go:""GO:0070129""(regulation of mitochondrial translation)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|rcsb pdb:8ANY|reactome:R-HSA-9836573|refseq:NP_573566.2|efo:""Orphanet:70472""|panther:PTHR46669(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RG4d0Ku1G5bXssHGdkTG4EIzMdI632	rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606	intact-crc:E0F79409523630AC|rigid:FJH73MVEkijYGYoCmE5GwZ2nNbk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14494	uniprotkb:A0A6B3VBG2	intact:EBI-2865290|uniprotkb:Q17RZ4|uniprotkb:B7ZKN8|uniprotkb:O60463|uniprotkb:O60457|uniprotkb:G3XA95|ensembl:ENSP00000302229.8	intact:EBI-2849663	psi-mi:plpp1_human(display_long)|uniprotkb:PLPP1(gene name)|psi-mi:PLPP1(display_short)|uniprotkb:LPP1(gene name synonym)|uniprotkb:Lipid phosphate phosphohydrolase 1(gene name synonym)|uniprotkb:PAP2-alpha(gene name synonym)|uniprotkb:PPAP2A(gene name synonym)|uniprotkb:Phosphatidate phosphohydrolase type 2a(gene name synonym)|uniprotkb:Phosphatidic acid phosphatase 2a(gene name synonym)	psi-mi:a0a6b3vbg2_yerpe(display_long)|uniprotkb:yapB(gene name)|psi-mi:yapB(display_short)|uniprotkb:y1345(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865287|imex:IM-13779-7082	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003702.2|refseq:NP_795714.1|ensembl:ENSG00000067113.17(gene)|ensembl:ENST00000307259.9(transcript)|go:""GO:0000810""(diacylglycerol diphosphate phosphatase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005901""(caveola)|go:""GO:0006644""(phospholipid metabolic process)|go:""GO:0006670""(sphingosine metabolic process)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0007165""(signal transduction)|go:""GO:0007200""(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:0008195""(phosphatidate phosphatase activity)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0030149""(sphingolipid catabolic process)|go:""GO:0030518""(nuclear receptor-mediated steroid hormone signaling pathway)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0042392""(sphingosine-1-phosphate phosphatase activity)|go:""GO:0042577""(lipid phosphatase activity)|go:""GO:0045121""(membrane raft)|go:""GO:0046839""(phospholipid dephosphorylation)|go:""GO:0052642""(lysophosphatidic acid phosphatase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106235""(ceramide-1-phosphate phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|mint:O14494|reactome:R-HSA-9845614|panther:PTHR10165(orthology-group)"	"interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|uniprotkb:A0A6B3T6Y5(uniprot-removed-ac)|go:""GO:0019867""(outer membrane)|interpro:IPR051551"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4/q14cUIMgYHHN+aOcmY/ssBnGM9606	rogid:jNPx4rqCv9bEZelj7jbp42kW+NY632	intact-crc:0B33EC2782454B23|rigid:+wm/EzicAnvkKk3Jute4KVQ/DAo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YKZ2	uniprotkb:O60711	intact:EBI-2860622|uniprotkb:Q74Q71|uniprotkb:Q0WJB6|uniprotkb:Q7CGA9|uniprotkb:A0A384LCM3	intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512.2	psi-mi:a0a5p8ykz2_yerpe(display_long)|uniprotkb:mra(gene name)|psi-mi:mra(display_short)|uniprotkb:D-alanyl-D-alanine-adding enzyme(gene name synonym)|uniprotkb:murF(gene name synonym)|uniprotkb:YPO0551(locus name)	psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865268|imex:IM-13779-7079	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005863(UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase)|refseq:WP_002210438.1|interpro:IPR051046|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008766""(UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0047480""(UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity)|go:""GO:0051301""(cell division)|go:""GO:0071555""(cell wall organization)|interpro:IPR035911|interpro:IPR036565|interpro:IPR036615|refseq:YP_002345622.1|panther:PTHR43024(orthology-group)"	"refseq:NP_001137467.1|refseq:NP_004802.1|refseq:NP_001294880.1|ensembl:ENSG00000110031.13(gene)|ensembl:ENST00000395074.7(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042995""(cell projection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|panther:PTHR24216(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fdMeHvUVX+djYjbRWAsbMX0u/YA632	rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606	intact-crc:17FD81670574C2FA|rigid:X5zVVlIo5NK5Jg8ezl1osd0jj2Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09960	uniprotkb:Q8D0M8	intact:EBI-721089|uniprotkb:Q6IAT6|uniprotkb:Q9UCT7|uniprotkb:B4DNQ9|uniprotkb:F8VV40|ensembl:ENSP00000228740.2	intact:EBI-2865342|uniprotkb:Q74TG9	"psi-mi:lkha4_human(display_long)|uniprotkb:""Leukotriene A(4) hydrolase""(gene name synonym)|uniprotkb:LTA4H(gene name)|psi-mi:LTA4H(display_short)|uniprotkb:LTA4(gene name synonym)|uniprotkb:Tripeptide aminopeptidase LTA4H(gene name synonym)"	psi-mi:q8d0m8_yerpe(display_long)|uniprotkb:YP_2189(locus name)|uniprotkb:y1936(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865339|imex:IM-13779-7086	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001243573.1|refseq:NP_000886.1|refseq:NP_001243572.1|refseq:XP_005268928.1|ensembl:ENSG00000111144.10(gene)|ensembl:ENST00000228740.7(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0004301""(epoxide hydrolase activity)|go:""GO:0004463""(leukotriene-A4 hydrolase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0008233""(peptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010043""(response to zinc ion)|go:""GO:0019370""(leukotriene biosynthetic process)|go:""GO:0019538""(protein metabolic process)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045148""(tripeptide aminopeptidase activity)|go:""GO:0060509""(type I pneumocyte differentiation)|go:""GO:0070006""(metalloaminopeptidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR012777(Leukotriene A-4 hydrolase/aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR015211(Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR034015|interpro:IPR038502|interpro:IPR042097|interpro:IPR045357|interpro:IPR049980|mint:P09960|rcsb pdb:1GW6|rcsb pdb:1H19|rcsb pdb:1HS6|rcsb pdb:1SQM|rcsb pdb:2R59|rcsb pdb:2VJ8|rcsb pdb:3B7R|rcsb pdb:3B7S|rcsb pdb:3B7T|rcsb pdb:3B7U|rcsb pdb:3CHO|rcsb pdb:3CHP|rcsb pdb:3CHQ|rcsb pdb:3CHR|rcsb pdb:3CHS|rcsb pdb:3FH5|rcsb pdb:3FH7|rcsb pdb:3FH8|rcsb pdb:3FHE|rcsb pdb:3FTS|rcsb pdb:3FTU|rcsb pdb:3FTV|rcsb pdb:3FTW|rcsb pdb:3FTX|rcsb pdb:3FTY|rcsb pdb:3FTZ|rcsb pdb:3FU0|rcsb pdb:3FU3|rcsb pdb:3FU5|rcsb pdb:3FU6|rcsb pdb:3FUD|rcsb pdb:3FUE|rcsb pdb:3FUF|rcsb pdb:3FUH|rcsb pdb:3FUI|rcsb pdb:3FUJ|rcsb pdb:3FUK|rcsb pdb:3FUL|rcsb pdb:3FUM|rcsb pdb:3FUN|rcsb pdb:3U9W|rcsb pdb:4DPR|rcsb pdb:4L2L|rcsb pdb:4MKT|rcsb pdb:4MS6|rcsb pdb:4R7L|rcsb pdb:4RSY|rcsb pdb:4RVB|rcsb pdb:5AEN|rcsb pdb:5BPP|rcsb pdb:5FWQ|rcsb pdb:5N3W|rcsb pdb:5NI2|rcsb pdb:5NI4|rcsb pdb:5NI6|rcsb pdb:5NIA|rcsb pdb:5NID|rcsb pdb:5NIE|rcsb pdb:6ENB|rcsb pdb:6ENC|rcsb pdb:6END|rcsb pdb:6O5H|rcsb pdb:7AUZ|rcsb pdb:7AV0|rcsb pdb:7AV1|rcsb pdb:7AV2|rcsb pdb:7KZE|rcsb pdb:7LLQ|rcsb pdb:8AVA|rcsb pdb:8AWH|rcsb pdb:8QOW|rcsb pdb:8QPN|rcsb pdb:8QQ4|rcsb pdb:8RX3|rcsb pdb:8RX7|rcsb pdb:8RX9|rcsb pdb:8TWX|reactome:R-HSA-2142691|reactome:R-HSA-6798695|reactome:R-HSA-9018676|reactome:R-HSA-9018681|reactome:R-HSA-9018896|reactome:R-HSA-9020265|reactome:R-HSA-9023661|panther:PTHR45726(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010230(SUF system FeS cluster assembly, SufC ATPase)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Qu84Rla6vl6zFvgcVCzHOa8mUbA9606	rogid:tCHqalIEgsXyx1fyyh/hX0QErHI632	intact-crc:97C8F9F05D590C49|rigid:QLpI+8xqi9sYK4322YiDVd+5HjE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09917	uniprotkb:Q8CLD8	intact:EBI-79934|uniprotkb:Q5JQ14|uniprotkb:E5FPY5|uniprotkb:E5FPY7|uniprotkb:E5FPY8|uniprotkb:B7ZLS0|ensembl:ENSP00000363512.2|ensembl:ENSP00000484468.1	intact:EBI-2851532|uniprotkb:Q74SW5	psi-mi:lox5_human(display_long)|uniprotkb:ALOX5(gene name)|psi-mi:ALOX5(display_short)|uniprotkb:LOG5(gene name synonym)|uniprotkb:Arachidonate 5-lipoxygenase(gene name synonym)	psi-mi:q8cld8_yerpe(display_long)|uniprotkb:icmF2(gene name)|psi-mi:icmF2(display_short)|uniprotkb:YP_2442(locus name)|uniprotkb:y1553(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865332|imex:IM-13779-7084	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000689.1|refseq:NP_001243082.1|panther:PTHR11771(orthology-group)|refseq:NP_001243083.1|dip:DIP-30950N|refseq:NP_001307790.1|ensembl:ENSG00000012779.12(gene)|ensembl:ENSG00000275565.4(gene)|ensembl:ENST00000374391.7(transcript)|ensembl:ENST00000610656.4(transcript)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0002232""(leukocyte chemotaxis involved in inflammatory response)|go:""GO:0002523""(leukocyte migration involved in inflammatory response)|go:""GO:0002540""(leukotriene production involved in inflammatory response)|go:""GO:0004051""(arachidonate 5-lipoxygenase activity)|go:""GO:0004052""(""arachidonate 12(S)-lipoxygenase activity"")|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005641""(nuclear envelope lumen)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006691""(leukotriene metabolic process)|go:""GO:0006959""(humoral immune response)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019369""(arachidonate metabolic process)|go:""GO:0019370""(leukotriene biosynthetic process)|go:""GO:0019372""(lipoxygenase pathway)|go:""GO:0030501""(positive regulation of bone mineralization)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034440""(lipid oxidation)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036403""(""arachidonate 8(S)-lipoxygenase activity"")|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042759""(long-chain fatty acid biosynthetic process)|go:""GO:0045598""(regulation of fat cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0061044""(negative regulation of vascular wound healing)|go:""GO:0061045""(negative regulation of wound healing)|go:""GO:0106014""(regulation of inflammatory response to wounding)|go:""GO:1900015""(regulation of cytokine production involved in inflammatory response)|go:""GO:1900407""(regulation of cellular response to oxidative stress)|go:""GO:1901753""(leukotriene A4 biosynthetic process)|go:""GO:1903426""(regulation of reactive oxygen species biosynthetic process)|go:""GO:1903573""(negative regulation of response to endoplasmic reticulum stress)|go:""GO:1903671""(negative regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1904999""(positive regulation of leukocyte adhesion to arterial endothelial cell)|go:""GO:2001301""(lipoxin biosynthetic process)|interpro:IPR000907(Lipoxygenase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|mint:P09917|rcsb pdb:3O8Y|rcsb pdb:3V92|rcsb pdb:3V98|rcsb pdb:3V99|rcsb pdb:6N2W|rcsb pdb:6NCF|rcsb pdb:7TTJ|rcsb pdb:7TTK|rcsb pdb:7TTL|reactome:R-HSA-2142688|reactome:R-HSA-2142691|reactome:R-HSA-2142700|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-9012546|reactome:R-HSA-9018676|reactome:R-HSA-9018682|reactome:R-HSA-9018896|reactome:R-HSA-9020265|reactome:R-HSA-9023661|reactome:R-HSA-9026286|reactome:R-HSA-9026290|reactome:R-HSA-9026403|reactome:R-HSA-9027604"	"interpro:IPR010623(Protein of unknown function DUF1215)|interpro:IPR009612(ImcF-related)|interpro:IPR017731(Type VI secretion system, IcmF)|interpro:IPR025743|interpro:IPR027417|go:""GO:0016020""(membrane)|interpro:IPR053156"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:kk3yqgz7R/Po68UpJpKJ3Rp6Ws89606	rogid:w2fthS2L39XGe86y6WdmUYcCZvo632	intact-crc:9A9F814E28A709FC|rigid:fNlEWtXRdhIE4o2u21j4JNGGOkE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PL04	uniprotkb:O95490	intact:EBI-2865317|uniprotkb:Q74WH8|uniprotkb:Q7CHB7|uniprotkb:Q0WHG1	intact:EBI-2865302|uniprotkb:Q9UKY5|uniprotkb:B1ALT9|uniprotkb:B1ALU0|uniprotkb:Q9UKY6|uniprotkb:B1ALT8|uniprotkb:O94882|uniprotkb:Q5VX76|uniprotkb:A5XEI2|uniprotkb:B1ALU2|uniprotkb:B1ALU4|uniprotkb:B1ALU5|uniprotkb:B1ALU6|ensembl:ENSP00000359752.3|ensembl:ENSP00000359763.1|intact:EBI-28986872	psi-mi:a0a2s9pl04_yerpe(display_long)|uniprotkb:YPO1248(locus name)	psi-mi:agrl2_human(display_long)|uniprotkb:ADGRL2(gene name)|psi-mi:ADGRL2(display_short)|uniprotkb:Calcium-independent alpha-latrotoxin receptor 2(gene name synonym)|uniprotkb:KIAA0786(gene name synonym)|uniprotkb:LEC1(gene name synonym)|uniprotkb:LPHH1(gene name synonym)|uniprotkb:LPHN2(gene name synonym)|uniprotkb:Latrophilin homolog 1(gene name synonym)|uniprotkb:Latrophilin-2(gene name synonym)|uniprotkb:Lectomedin-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865314|imex:IM-13779-7085	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR014462(Mu-like prophage protein gp45)|interpro:IPR053861|refseq:WP_002215460.1|refseq:YP_002346277.1	"refseq:NP_036434.1|refseq:XP_005270723.1|refseq:NP_001284633.1|refseq:NP_001284634.1|refseq:NP_001284635.1|refseq:NP_001317574.1|refseq:XP_016856276.1|ensembl:ENSG00000117114.21(gene)|ensembl:ENST00000370717.6(transcript)|ensembl:ENST00000370728.5(transcript)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016524""(latrotoxin receptor activity)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR017981|interpro:IPR017983|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159|interpro:IPR046338|mint:O95490|panther:PTHR12011(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kdNqWWV8OUVzrmTW+39J1rZOOfk632	rogid:WkTs1zEQmAT82KxUL2+V7KG74UQ9606	intact-crc:EB61BE4890F0616E|rigid:PLu9GrOHrHeXQxo58s7bsHn8QyI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D078	uniprotkb:P09917	intact:EBI-2840175	intact:EBI-79934|uniprotkb:Q5JQ14|uniprotkb:E5FPY5|uniprotkb:E5FPY7|uniprotkb:E5FPY8|uniprotkb:B7ZLS0|ensembl:ENSP00000363512.2|ensembl:ENSP00000484468.1	psi-mi:q8d078_yerpe(display_long)|uniprotkb:gnd(gene name)|psi-mi:gnd(display_short)|uniprotkb:y2629(locus name)	psi-mi:lox5_human(display_long)|uniprotkb:ALOX5(gene name)|psi-mi:ALOX5(display_short)|uniprotkb:LOG5(gene name synonym)|uniprotkb:Arachidonate 5-lipoxygenase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865325|imex:IM-13779-7083	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR013328(Dehydrogenase, multihelical)|go:""GO:0004616""(""phosphogluconate dehydrogenase (decarboxylating) activity"")|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0016054""(organic acid catabolic process)|go:""GO:0019521""(D-gluconate metabolic process)|go:""GO:0050661""(NADP binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR036291"	"refseq:NP_000689.1|refseq:NP_001243082.1|panther:PTHR11771(orthology-group)|refseq:NP_001243083.1|dip:DIP-30950N|refseq:NP_001307790.1|ensembl:ENSG00000012779.12(gene)|ensembl:ENSG00000275565.4(gene)|ensembl:ENST00000374391.7(transcript)|ensembl:ENST00000610656.4(transcript)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0002232""(leukocyte chemotaxis involved in inflammatory response)|go:""GO:0002523""(leukocyte migration involved in inflammatory response)|go:""GO:0002540""(leukotriene production involved in inflammatory response)|go:""GO:0004051""(arachidonate 5-lipoxygenase activity)|go:""GO:0004052""(""arachidonate 12(S)-lipoxygenase activity"")|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005641""(nuclear envelope lumen)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006691""(leukotriene metabolic process)|go:""GO:0006959""(humoral immune response)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019369""(arachidonate metabolic process)|go:""GO:0019370""(leukotriene biosynthetic process)|go:""GO:0019372""(lipoxygenase pathway)|go:""GO:0030501""(positive regulation of bone mineralization)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034440""(lipid oxidation)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0036403""(""arachidonate 8(S)-lipoxygenase activity"")|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042759""(long-chain fatty acid biosynthetic process)|go:""GO:0045598""(regulation of fat cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0061044""(negative regulation of vascular wound healing)|go:""GO:0061045""(negative regulation of wound healing)|go:""GO:0106014""(regulation of inflammatory response to wounding)|go:""GO:1900015""(regulation of cytokine production involved in inflammatory response)|go:""GO:1900407""(regulation of cellular response to oxidative stress)|go:""GO:1901753""(leukotriene A4 biosynthetic process)|go:""GO:1903426""(regulation of reactive oxygen species biosynthetic process)|go:""GO:1903573""(negative regulation of response to endoplasmic reticulum stress)|go:""GO:1903671""(negative regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1904999""(positive regulation of leukocyte adhesion to arterial endothelial cell)|go:""GO:2001301""(lipoxin biosynthetic process)|interpro:IPR000907(Lipoxygenase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|mint:P09917|rcsb pdb:3O8Y|rcsb pdb:3V92|rcsb pdb:3V98|rcsb pdb:3V99|rcsb pdb:6N2W|rcsb pdb:6NCF|rcsb pdb:7TTJ|rcsb pdb:7TTK|rcsb pdb:7TTL|reactome:R-HSA-2142688|reactome:R-HSA-2142691|reactome:R-HSA-2142700|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-9012546|reactome:R-HSA-9018676|reactome:R-HSA-9018682|reactome:R-HSA-9018896|reactome:R-HSA-9020265|reactome:R-HSA-9023661|reactome:R-HSA-9026286|reactome:R-HSA-9026290|reactome:R-HSA-9026403|reactome:R-HSA-9027604"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:t03DBqO03/Ad8aGwPnpOxjNYFOQ632	rogid:kk3yqgz7R/Po68UpJpKJ3Rp6Ws89606	intact-crc:0F7B8F1928B50DB1|rigid:ODWHgKhhTL1pWEkgsi7ia8rn7Bs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D194	uniprotkb:Q9UHB6	intact:EBI-2847851|uniprotkb:Q74XR4	intact:EBI-351479|uniprotkb:Q2TAN7|uniprotkb:Q9BVF2|uniprotkb:Q9H8J1|uniprotkb:Q9HBN5|uniprotkb:Q9NX96|uniprotkb:Q9NXC3|uniprotkb:Q9NXU6|uniprotkb:Q9P0H8|uniprotkb:Q9UHB5|uniprotkb:B2RB09|uniprotkb:Q59FE8|ensembl:ENSP00000340184.4	psi-mi:q8d194_yerpe(display_long)|uniprotkb:dAK1_1(gene name)|psi-mi:dAK1_1(display_short)|uniprotkb:YP_0337(locus name)|uniprotkb:y0840(locus name)	psi-mi:lima1_human(display_long)|uniprotkb:PP624(orf name)|uniprotkb:LIMA1(gene name)|psi-mi:LIMA1(display_short)|uniprotkb:SREBP3(gene name synonym)|uniprotkb:Epithelial protein lost in neoplasm(gene name synonym)|uniprotkb:EPLIN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865378|imex:IM-13779-7089	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004006(Dak kinase)|go:""GO:0004371""(glycerone kinase activity)|go:""GO:0006071""(glycerol metabolic process)|interpro:IPR050861"	"refseq:NP_001107018.1|refseq:NP_001107019.1|refseq:NP_057441.1|refseq:NP_001230704.1|ensembl:ENSG00000050405.14(gene)|ensembl:ENST00000341247.9(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0003785""(actin monomer binding)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016477""(cell migration)|go:""GO:0030299""(intestinal cholesterol absorption)|go:""GO:0030835""(negative regulation of actin filament depolymerization)|go:""GO:0031526""(brush border membrane)|go:""GO:0031529""(ruffle organization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0045296""(cadherin binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:1902018""(negative regulation of cilium assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028740|mint:Q9UHB6|rcsb pdb:2D8Y|refseq:XP_011536757.1|refseq:XP_016874919.1|dip:DIP-29633N|panther:PTHR24206(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:PGSwAYXIFUUnJmzpLaHT1vlvQxc632	rogid:sHqhe21LVzLJXgDMH6IcWukKNHE9606	intact-crc:36E69B2CA27FA1DE|rigid:Sd6Oj0rpPowJumnketKw3of6aUg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43034	uniprotkb:A0A5P8YFD8	intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378.4|ensembl:ENSP00000461087.2|ensembl:ENSP00000501969.1|ensembl:ENSP00000502031.1|ensembl:ENSP00000502577.1|ensembl:ENSP00000502735.1|ensembl:ENSP00000502843.1|ensembl:ENSP00000519277.1|ensembl:ENSP00000519278.1	intact:EBI-2844797|uniprotkb:Q74TW8|uniprotkb:A0A0H2W658|uniprotkb:Q7CIM3|uniprotkb:A0A384L807	psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym)	psi-mi:a0a5p8yfd8_yerpe(display_long)|uniprotkb:trpE(gene name)|psi-mi:trpE(display_short)|uniprotkb:YPO2208(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865350|imex:IM-13779-7091	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:217385""|efo:""Orphanet:531""|efo:""Orphanet:95232""|efo:""Orphanet:99796""|ensembl:ENSG00000007168.15(gene)|ensembl:ENST00000397195.10(transcript)|ensembl:ENST00000576586.6(transcript)|ensembl:ENST00000675202.1(transcript)|ensembl:ENST00000675331.1(transcript)|ensembl:ENST00000675390.1(transcript)|ensembl:ENST00000676098.1(transcript)|ensembl:ENST00000676188.1(transcript)|ensembl:ENST00000713986.1(transcript)|ensembl:ENST00000713987.1(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000235""(astral microtubule)|go:""GO:0000776""(kinetochore)|go:""GO:0001667""(ameboidal-type cell migration)|go:""GO:0001675""(acrosome assembly)|go:""GO:0001764""(neuron migration)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0005938""(cell cortex)|go:""GO:0007017""(microtubule-based process)|go:""GO:0007097""(nuclear migration)|go:""GO:0007254""(JNK cascade)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007281""(germ cell development)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007611""(learning or memory)|go:""GO:0008017""(microtubule binding)|go:""GO:0008090""(retrograde axonal transport)|go:""GO:0008201""(heparin binding)|go:""GO:0008247""(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0009306""(protein secretion)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0017145""(stem cell division)|go:""GO:0019226""(transmission of nerve impulse)|go:""GO:0021540""(corpus callosum morphogenesis)|go:""GO:0021766""(hippocampus development)|go:""GO:0021819""(layer formation in cerebral cortex)|go:""GO:0021895""(cerebral cortex neuron differentiation)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031514""(motile cilium)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032420""(stereocilium)|go:""GO:0034452""(dynactin binding)|go:""GO:0036035""(osteoclast development)|go:""GO:0038026""(reelin-mediated signaling pathway)|go:""GO:0040019""(positive regulation of embryonic development)|go:""GO:0042249""(establishment of planar polarity of embryonic epithelium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0046469""(platelet activating factor metabolic process)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048854""(brain morphogenesis)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0051012""(microtubule sliding)|go:""GO:0051081""(nuclear membrane disassembly)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051660""(establishment of centrosome localization)|go:""GO:0051661""(maintenance of centrosome location)|go:""GO:0060117""(auditory receptor cell development)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0070840""(dynein complex binding)|go:""GO:0090102""(cochlea development)|go:""GO:0090176""(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:""GO:0090724""(central region of growth cone)|go:""GO:0097529""(myeloid leukocyte migration)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140650""(radial glia-guided pyramidal neuron migration)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1904936""(interneuron migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|interpro:IPR050349|mint:P43034|rcsb pdb:7MT1|rcsb pdb:8DYU|rcsb pdb:8DYV|rcsb pdb:8FDT|rcsb pdb:8FDU|rcsb pdb:8PQW|rcsb pdb:8PQY|rcsb pdb:8PQZ|rcsb pdb:8PTK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|refseq:NP_000421.1|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|panther:PTHR44129(orthology-group)"	"interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR019999|interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR005257(Anthranilate synthase component I, TrpE)|interpro:IPR015890(Chorismate binding, C-terminal)|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004049""(anthranilate synthase activity)|go:""GO:0046872""(metal ion binding)|refseq:YP_002347179.1|panther:PTHR11236(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606	rogid:4yY3KOTpkixAVvXxxbToZJUfRYM632	intact-crc:B62AAE6C4FEE4B85|rigid:G4g5UFopPkFSKr4+23syGxu64wQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1J9	uniprotkb:Q9UPQ0	intact:EBI-2844009|uniprotkb:Q74R75	intact:EBI-2687222|uniprotkb:Q8N3S9|uniprotkb:Q5H9S8|uniprotkb:Q6PJ44|uniprotkb:Q5CZB6|uniprotkb:Q5CZB1|uniprotkb:Q503B5|uniprotkb:Q8N6M2|uniprotkb:Q68E07|uniprotkb:Q7Z3G5|uniprotkb:A8MXC3|uniprotkb:E9PHM7|intact:EBI-10977823|ensembl:ENSP00000316891.7	psi-mi:q8d1j9_yerpe(display_long)|uniprotkb:uvrD(gene name)|psi-mi:uvrD(display_short)|uniprotkb:DNA 3'-5' helicase II(gene name synonym)|uniprotkb:YP_3206(locus name)|uniprotkb:y0389(locus name)	psi-mi:limc1_human(display_long)|uniprotkb:KIAA1102(gene name synonym)|uniprotkb:LIMCH1(gene name)|psi-mi:LIMCH1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865364|imex:IM-13779-7090	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005753(DNA helicase, ATP-dependent, UvrD type)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016787""(hydrolase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR013986(DNA helicase, DEXX box type)"	"refseq:NP_001106188.1|refseq:NP_001106189.1|refseq:NP_001106190.1|refseq:NP_001106191.1|refseq:NP_055803.2|refseq:NP_001276051.1|refseq:NP_001276053.1|refseq:NP_001317601.1|refseq:NP_001317603.1|refseq:NP_001317713.1|refseq:NP_001317715.1|ensembl:ENSG00000064042.18(gene)|ensembl:ENST00000313860.12(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032034""(myosin II head/neck binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060327""(cytoplasmic actin-based contraction involved in cell motility)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR031865|interpro:IPR036872|mint:Q9UPQ0|panther:PTHR15551(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PolYsqnEbJnfKp6krRc+FLB+mdg632	rogid:neDT1Rx97o6shpmtkOqJy31ueTA9606	intact-crc:D84EF8317DC97117|rigid:JBPZo9MGTLsAfNKTy6932j5Va5E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43034	uniprotkb:P58680	intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378.4|ensembl:ENSP00000461087.2|ensembl:ENSP00000501969.1|ensembl:ENSP00000502031.1|ensembl:ENSP00000502577.1|ensembl:ENSP00000502735.1|ensembl:ENSP00000502843.1|ensembl:ENSP00000519277.1|ensembl:ENSP00000519278.1	intact:EBI-2840970|uniprotkb:Q0WJI8	psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym)	psi-mi:isph_yerpe(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:YPO0477(locus name)|uniprotkb:y3697(locus name)|uniprotkb:YP_3702(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865357|imex:IM-13779-7087	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:217385""|efo:""Orphanet:531""|efo:""Orphanet:95232""|efo:""Orphanet:99796""|ensembl:ENSG00000007168.15(gene)|ensembl:ENST00000397195.10(transcript)|ensembl:ENST00000576586.6(transcript)|ensembl:ENST00000675202.1(transcript)|ensembl:ENST00000675331.1(transcript)|ensembl:ENST00000675390.1(transcript)|ensembl:ENST00000676098.1(transcript)|ensembl:ENST00000676188.1(transcript)|ensembl:ENST00000713986.1(transcript)|ensembl:ENST00000713987.1(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000235""(astral microtubule)|go:""GO:0000776""(kinetochore)|go:""GO:0001667""(ameboidal-type cell migration)|go:""GO:0001675""(acrosome assembly)|go:""GO:0001764""(neuron migration)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0005938""(cell cortex)|go:""GO:0007017""(microtubule-based process)|go:""GO:0007097""(nuclear migration)|go:""GO:0007254""(JNK cascade)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0007281""(germ cell development)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007611""(learning or memory)|go:""GO:0008017""(microtubule binding)|go:""GO:0008090""(retrograde axonal transport)|go:""GO:0008201""(heparin binding)|go:""GO:0008247""(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0009306""(protein secretion)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0017145""(stem cell division)|go:""GO:0019226""(transmission of nerve impulse)|go:""GO:0021540""(corpus callosum morphogenesis)|go:""GO:0021766""(hippocampus development)|go:""GO:0021819""(layer formation in cerebral cortex)|go:""GO:0021895""(cerebral cortex neuron differentiation)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031514""(motile cilium)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032420""(stereocilium)|go:""GO:0034452""(dynactin binding)|go:""GO:0036035""(osteoclast development)|go:""GO:0038026""(reelin-mediated signaling pathway)|go:""GO:0040019""(positive regulation of embryonic development)|go:""GO:0042249""(establishment of planar polarity of embryonic epithelium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043622""(cortical microtubule organization)|go:""GO:0045505""(dynein intermediate chain binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0046469""(platelet activating factor metabolic process)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048854""(brain morphogenesis)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0051012""(microtubule sliding)|go:""GO:0051081""(nuclear membrane disassembly)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051660""(establishment of centrosome localization)|go:""GO:0051661""(maintenance of centrosome location)|go:""GO:0060117""(auditory receptor cell development)|go:""GO:0061003""(positive regulation of dendritic spine morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070507""(regulation of microtubule cytoskeleton organization)|go:""GO:0070840""(dynein complex binding)|go:""GO:0090102""(cochlea development)|go:""GO:0090176""(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:""GO:0090724""(central region of growth cone)|go:""GO:0097529""(myeloid leukocyte migration)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140650""(radial glia-guided pyramidal neuron migration)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1904936""(interneuron migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|interpro:IPR050349|mint:P43034|rcsb pdb:7MT1|rcsb pdb:8DYU|rcsb pdb:8DYV|rcsb pdb:8FDT|rcsb pdb:8FDU|rcsb pdb:8PQW|rcsb pdb:8PQY|rcsb pdb:8PQZ|rcsb pdb:8PTK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|refseq:NP_000421.1|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|panther:PTHR44129(orthology-group)"	"interpro:IPR003451(LytB protein)|refseq:YP_002345550.1|go:""GO:0016114""(terpenoid biosynthetic process)|go:""GO:0019288""(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:""GO:0046872""(metal ion binding)|go:""GO:0050992""(dimethylallyl diphosphate biosynthetic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0051745""(4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity)|refseq:WP_002210506.1|panther:PTHR30426(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606	rogid:RilZ1EP/J2M/K79PNEHVWA2tz2c632	intact-crc:6B7F346770577921|rigid:DebToriiYy/3BfPA3qnzxgQ7z1o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UPQ0	uniprotkb:A0A3N4B652	intact:EBI-2687222|uniprotkb:Q8N3S9|uniprotkb:Q5H9S8|uniprotkb:Q6PJ44|uniprotkb:Q5CZB6|uniprotkb:Q5CZB1|uniprotkb:Q503B5|uniprotkb:Q8N6M2|uniprotkb:Q68E07|uniprotkb:Q7Z3G5|uniprotkb:A8MXC3|uniprotkb:E9PHM7|intact:EBI-10977823|ensembl:ENSP00000316891.7	intact:EBI-2841456|uniprotkb:Q74UD2|uniprotkb:A0A0H2W5A2|uniprotkb:Q7CIY7	psi-mi:limc1_human(display_long)|uniprotkb:KIAA1102(gene name synonym)|uniprotkb:LIMCH1(gene name)|psi-mi:LIMCH1(display_short)	psi-mi:a0a3n4b652_yerpe(display_long)|uniprotkb:cheA(gene name)|psi-mi:cheA(display_short)|uniprotkb:YPO1666(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865371|imex:IM-13779-7088	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001106188.1|refseq:NP_001106189.1|refseq:NP_001106190.1|refseq:NP_001106191.1|refseq:NP_055803.2|refseq:NP_001276051.1|refseq:NP_001276053.1|refseq:NP_001317601.1|refseq:NP_001317603.1|refseq:NP_001317713.1|refseq:NP_001317715.1|ensembl:ENSG00000064042.18(gene)|ensembl:ENST00000313860.12(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032034""(myosin II head/neck binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060327""(cytoplasmic actin-based contraction involved in cell motility)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR031865|interpro:IPR036872|mint:Q9UPQ0|panther:PTHR15551(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR002545(CheW-like protein)|interpro:IPR015162(CheY binding)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR008207(""Signal transduction histidine kinase, phosphotransfer (Hpt) region"")|interpro:IPR004105(Signal transduction histidine kinase, subgroup, homodimeric)|interpro:IPR005467(Signal transduction histidine kinase, core)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006935""(chemotaxis)|refseq:YP_002346673.1|interpro:IPR035891|interpro:IPR036061|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037006|interpro:IPR051315|panther:PTHR43395(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:neDT1Rx97o6shpmtkOqJy31ueTA9606	rogid:KztfI7bmNuR6U1Zo6bOZct0DtBc632	intact-crc:1F5630CD3BE824F0|rigid:/EZAjDaTsoADec8o6bBfHYsSlIs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96PV6	uniprotkb:A0A5P8YAL1	intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|ensembl:ENSP00000318374.5|ensembl:ENSP00000478337.1|ensembl:ENSP00000478975.1|ensembl:ENSP00000480663.1|intact:EBI-28984630|uniprotkb:A0A087WTE7	intact:EBI-2847693|uniprotkb:Q74QT5|uniprotkb:A0A0H2W741|uniprotkb:Q7CFS1|uniprotkb:A0A384LBQ5	psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym)	psi-mi:a0a5p8yal1_yerpe(display_long)|uniprotkb:yhjW(gene name)|psi-mi:yhjW(display_short)|uniprotkb:YPO4013(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865408|imex:IM-13779-7093	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_443157.1|refseq:XP_011524717.1|ensembl:ENSG00000167615.18(gene)|ensembl:ENSG00000274305.4(gene)|ensembl:ENSG00000276458.4(gene)|ensembl:ENSG00000276681.4(gene)|ensembl:ENST00000326764.10(transcript)|ensembl:ENST00000617180.4(transcript)|ensembl:ENST00000621306.4(transcript)|ensembl:ENST00000622672.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0032991""(protein-containing complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR045107|mint:Q96PV6|panther:PTHR12436(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR012549(Protein of unknown function DUF1705)|interpro:IPR000917(Sulphatase)|refseq:WP_002209571.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009244""(lipopolysaccharide core region biosynthetic process)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0043838""(""phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity"")|interpro:IPR040423|refseq:YP_002348879.1|panther:PTHR30443(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kwgKuV5NW0hITukndsYeyQHTdd09606	rogid:HkeTpMUkl5+g00S4VZSWIDHQ28c632	intact-crc:3B800CEE83484A01|rigid:R/uN2nNiCBFj7DgHGXiIBL9sHMM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q969G2	uniprotkb:P28808	intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726.2	intact:EBI-2860941	psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short)	psi-mi:lcrf_yerpe(display_long)|uniprotkb:lcrF(gene name)|psi-mi:lcrF(display_short)|uniprotkb:virF(gene name synonym)|uniprotkb:YPCD1.49(locus name)|uniprotkb:y5029(locus name)|uniprotkb:y0032(locus name)|uniprotkb:YP_pCD34(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865385|imex:IM-13779-7092	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-29454N|ensembl:ENSG00000121454.6(gene)|ensembl:ENST00000263726.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001890""(placenta development)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0008045""(motor neuron axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008327""(methyl-CpG binding)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0021526""(medial motor column neuron differentiation)|go:""GO:0030182""(neuron differentiation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR047956|interpro:IPR049594|interpro:IPR050453|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553|refseq:NP_203129.1|efo:""Orphanet:226307""|efo:""Orphanet:85442""|efo:""Orphanet:95494""|efo:""Orphanet:95496""|panther:PTHR24208(orthology-group)"	"refseq:NP_395183.1|refseq:NP_857733.1|refseq:NP_857928.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR018062|interpro:IPR018060|interpro:IPR020449|interpro:IPR054015|mint:P28808|refseq:WP_002212931.1|interpro:IPR050204|interpro:IPR037923|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0043565""(sequence-specific DNA binding)|panther:PTHR43280(orthology-group)"	"psi-mi:""MI:0469""(intact)"	crc64:6499F38E78B79FD1	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606	rogid:yVpO1P2FvEEro9oVZYYjR90kz/M632	intact-crc:942DC5E1B3A4D507|rigid:6RcDbl65keiFNGdyWrAlgIeAegE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q74R28	uniprotkb:P17931	intact:EBI-2844649|uniprotkb:Q8D1I8	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:ugpc_yerpe(display_long)|uniprotkb:ugpC(gene name)|psi-mi:ugpC(display_short)|uniprotkb:YPO3793(locus name)|uniprotkb:y0437(locus name)|uniprotkb:YP_3256(locus name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865422|imex:IM-13779-7096	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR040582|interpro:IPR015855(ABC transporter, maltose/maltodextrin import, MalK)|interpro:IPR027417|refseq:WP_002211523.1|go:""GO:0001407""(glycerophosphodiester transmembrane transport)|go:""GO:0005524""(ATP binding)|go:""GO:0008643""(carbohydrate transport)|go:""GO:0015430""(ABC-type glycerol-3-phosphate transporter activity)|go:""GO:0015794""(glycerol-3-phosphate transmembrane transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055052""(""ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing"")|interpro:IPR047641|refseq:YP_002348670.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR43875(orthology-group)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:NtRUgbRI2HE2UzUkxbSvyMnRkao632	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:8834F5A19BD5BE76|rigid:zVTDmGvBfEkgw2IGFpJPLjzzy3g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCQ2	uniprotkb:Q96PV6	intact:EBI-2850142|uniprotkb:Q0WCY7	intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|ensembl:ENSP00000318374.5|ensembl:ENSP00000478337.1|ensembl:ENSP00000478975.1|ensembl:ENSP00000480663.1|intact:EBI-28984630|uniprotkb:A0A087WTE7	psi-mi:pur4_yerpe(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:YPO2921(locus name)|uniprotkb:YP_2536(locus name)|uniprotkb:y1309(locus name)	psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865415|imex:IM-13779-7094	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR029062|refseq:WP_002211561.1|interpro:IPR040707|go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609|refseq:YP_002347851.1|panther:PTHR10099(orthology-group)"	"refseq:NP_443157.1|refseq:XP_011524717.1|ensembl:ENSG00000167615.18(gene)|ensembl:ENSG00000274305.4(gene)|ensembl:ENSG00000276458.4(gene)|ensembl:ENSG00000276681.4(gene)|ensembl:ENST00000326764.10(transcript)|ensembl:ENST00000617180.4(transcript)|ensembl:ENST00000621306.4(transcript)|ensembl:ENST00000622672.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0032991""(protein-containing complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR045107|mint:Q96PV6|panther:PTHR12436(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8JTbD5hWDWC5PK7sHtiOwqqdyHs632	rogid:kwgKuV5NW0hITukndsYeyQHTdd09606	intact-crc:A46CF1698AB98ED6|rigid:gqOgGcfQLVIktwTRsL1q8BI0uRY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96PV6	uniprotkb:A0A3G5L7Y0	intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|ensembl:ENSP00000318374.5|ensembl:ENSP00000478337.1|ensembl:ENSP00000478975.1|ensembl:ENSP00000480663.1|intact:EBI-28984630|uniprotkb:A0A087WTE7	intact:EBI-2853824	psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym)	psi-mi:a0a3g5l7y0_yerpe(display_long)|uniprotkb:sfcA2(gene name)|psi-mi:sfcA2(display_short)|uniprotkb:YP_2657(locus name)|uniprotkb:y1449(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865401|imex:IM-13779-7095	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_443157.1|refseq:XP_011524717.1|ensembl:ENSG00000167615.18(gene)|ensembl:ENSG00000274305.4(gene)|ensembl:ENSG00000276458.4(gene)|ensembl:ENSG00000276681.4(gene)|ensembl:ENST00000326764.10(transcript)|ensembl:ENST00000617180.4(transcript)|ensembl:ENST00000621306.4(transcript)|ensembl:ENST00000622672.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0032991""(protein-containing complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR045107|mint:Q96PV6|panther:PTHR12436(orthology-group)"	"interpro:IPR051674|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|interpro:IPR012188(Malic enzyme, phosphate acetyl/butaryl transferase)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR036291|interpro:IPR037062|interpro:IPR042112|interpro:IPR042113|uniprotkb:A0A6B3T265(uniprot-removed-ac)|go:""GO:0004470""(malic enzyme activity)|go:""GO:0006108""(malate metabolic process)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051287""(NAD binding)|interpro:IPR045213|refseq:WP_002224829.1|interpro:IPR046346"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kwgKuV5NW0hITukndsYeyQHTdd09606	rogid:stWUfKx3Suo1T8GcyMQBEsNHMII632	intact-crc:AB0BE936A7DA462B|rigid:R+upn+gEoNgojcZGOkja5O/gv/8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W1Q5	uniprotkb:P17931	intact:EBI-2853792|uniprotkb:Q74YR1|uniprotkb:Q9ZH03|uniprotkb:Q7ARG4	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:a0a0h2w1q5_yerpe(display_long)|uniprotkb:YPMT1.06c(locus name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865443|imex:IM-13779-7100	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR053171|interpro:IPR015406(Protein of unknown function DUF1983)|interpro:IPR021034|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_395342.1|interpro:IPR032876|interpro:IPR036116|panther:PTHR36251(orthology-group)	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:lrUp2DqpgnBpUzbz9OhqYqyoRY4632	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:159642052A616D43|rigid:XTknJ1KUh33IC4p2XPN/AHA351E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ02	uniprotkb:P17931	intact:EBI-2855503|uniprotkb:Q0WJX8|uniprotkb:Q7CKN8|uniprotkb:Q74XE7	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	"psi-mi:rhab_yerpe(display_long)|uniprotkb:rhaB(gene name)|psi-mi:rhaB(display_short)|uniprotkb:Rhamnulose kinase(gene name synonym)|uniprotkb:YPO0330(locus name)|uniprotkb:y0587(locus name)|uniprotkb:YP_0485(locus name)|uniprotkb:L-rhamnulose 1-kinase(gene name synonym)|uniprotkb:""ATP:L-rhamnulose phosphotransferase""(gene name synonym)"	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865436|imex:IM-13779-7097	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018485|interpro:IPR018484|interpro:IPR013449(Rhamnulokinase)|interpro:IPR000577(Carbohydrate kinase, FGGY)|refseq:WP_002209105.1|go:""GO:0004370""(glycerol kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008993""(rhamnulokinase activity)|go:""GO:0019301""(rhamnose catabolic process)|interpro:IPR043129|refseq:YP_002345410.1|panther:PTHR10196(orthology-group)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:lL9J4K2xcNV9zW+r3/RgTvxRYeQ632	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:5929A1B6468B058D|rigid:xkPVZfkhu/yK6Hyt/JewO7VwJX8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PME5	uniprotkb:P17931	intact:EBI-2843109|uniprotkb:Q74XQ1|uniprotkb:A0A0H2W1F9|uniprotkb:Q7CKB7|uniprotkb:A0A384KR24	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:a0a2s9pme5_yerpe(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:YPO3337(locus name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865457|imex:IM-13779-7099	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|go:""GO:0004239""(initiator methionyl aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|refseq:WP_002209416.1|interpro:IPR036005|refseq:YP_002348233.1|panther:PTHR43330(orthology-group)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:NidRuZki0mfu471s0HwP6hVVvx4632	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:F44280471F38DAD4|rigid:Qb6LF5mWfCde53hn9PTGxaI63jQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:Q8ZHG8	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2849252|uniprotkb:Q0WIB1	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:spea_yerpe(display_long)|uniprotkb:speA(gene name)|psi-mi:speA(display_short)|uniprotkb:YPO0929(locus name)|uniprotkb:y3313(locus name)|uniprotkb:YP_3513(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865429|imex:IM-13779-7101	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR002985(Arginine decarboxylase)|interpro:IPR022657|interpro:IPR022644|interpro:IPR022653|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|interpro:IPR029066|interpro:IPR040634|go:""GO:0006527""(arginine catabolic process)|go:""GO:0008295""(spermidine biosynthetic process)|go:""GO:0008792""(arginine decarboxylase activity)|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0046872""(metal ion binding)|interpro:IPR041128|refseq:WP_002209969.1|refseq:YP_002345977.1|panther:PTHR43295(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:WJK/NuC1y1WJhbzgBDwly+QaYwA632	intact-crc:7B9443B644C666D8|rigid:zvMHLRt3VD7g8bmf9T0TpRuHAhY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1P6	uniprotkb:P17931	intact:EBI-2839854	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:q8d1p6_yerpe(display_long)|uniprotkb:tcaC1(gene name)|psi-mi:tcaC1(display_short)|uniprotkb:y0185(locus name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865450|imex:IM-13779-7098	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003284(Salmonella virulence plasmid 65kDa B protein)|interpro:IPR022044|interpro:IPR022045|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|interpro:IPR028994"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:O/TCvNvvMc3GrD6oFI13BOD7NL8632	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:BD07190847EFD742|rigid:Y+LnV2hWHTJQtjSu8BaKRnfEa/c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A3N4B351	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2841075|uniprotkb:A0A0H2W410|uniprotkb:A0A384KQ38|uniprotkb:Q74VQ8|uniprotkb:Q7CHH9	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:a0a3n4b351_yerpe(display_long)|uniprotkb:poxB(gene name)|psi-mi:poxB(display_short)|uniprotkb:Pyruvate oxidase(gene name synonym)|uniprotkb:""Pyruvate:ubiquinone-8 oxidoreductase""(gene name synonym)|uniprotkb:YPO1358(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865464|imex:IM-13779-7102	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR047210|interpro:IPR047211|interpro:IPR047212|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|refseq:YP_002346381.1|interpro:IPR029035|interpro:IPR029061|interpro:IPR000399(TPP-binding enzymes, conserved site)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0008289""(lipid binding)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0042867""(pyruvate catabolic process)|go:""GO:0048039""(ubiquinone binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0052737""(""pyruvate dehydrogenase (quinone) activity"")|refseq:WP_002211361.1|interpro:IPR044261|panther:PTHR42981(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:mZMbCbWjPalRuN2dmEN5FHwrJO4632	intact-crc:9D5C58369B2BD43E|rigid:adGCsOVw2RFmbKMIV0iap8Ryh2k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YCV0	uniprotkb:P17931	intact:EBI-2847775|uniprotkb:Q74Q84|uniprotkb:Q0WIC7|uniprotkb:Q7CGS8|uniprotkb:A0A384L1X8	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:a0a5p8ycv0_yerpe(display_long)|uniprotkb:YPO0913(locus name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865483|imex:IM-13779-7103	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|refseq:WP_002209955.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009396""(folic acid-containing compound biosynthetic process)|go:""GO:0030272""(5-formyltetrahydrofolate cyclo-ligase activity)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|interpro:IPR024185|interpro:IPR037171|refseq:YP_002345961.1|panther:PTHR23407(orthology-group)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:10+1hunnZ1E8GkdgkFMuY64dDRY632	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:EBA47B9BBD971FF1|rigid:iQJH7Ci6t0GLLWCGLbvxzENVPSc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WHB9	uniprotkb:P17931	intact:EBI-2865474|uniprotkb:Q74VK6|uniprotkb:Q7CHE5|uniprotkb:A0A0H2W3B9|uniprotkb:A0A380PMW6	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:q0whb9_yerpe(display_long)|uniprotkb:YPO1293(locus name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865471|imex:IM-13779-7105	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR025997|interpro:IPR028082|refseq:WP_002208804.1|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030313""(cell envelope)|refseq:YP_002346319.1"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:005N4coCeNHtTXwgUb8LFuJEQkQ632	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:48D28660CC9BB6A0|rigid:GWFvZL2D+ZVBrWtXpZ54GkIIJfE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A380PJW4	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2847196|uniprotkb:Q0WI94|uniprotkb:Q7CGR6	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:a0a380pjw4_yerpe(display_long)|uniprotkb:YPO0947(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865490|imex:IM-13779-7104	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR020974|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|interpro:IPR028994|refseq:WP_002224905.1|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0016740""(transferase activity)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0044164""(host cell cytosol)|go:""GO:0046872""(metal ion binding)|go:""GO:0090729""(toxin activity)|interpro:IPR038383|refseq:YP_002345994.1|interpro:IPR049824"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:3Aj0qy9DiLKc8Bx9KbIJWyE+XAM632	intact-crc:72F5C062FECE13D7|rigid:n0WMBxBoDsV5yRvHQ3tIHb5CS7Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YAV7	uniprotkb:P17931	intact:EBI-2839792|uniprotkb:Q74QU9|uniprotkb:Q0WA24|uniprotkb:Q7CG16|uniprotkb:A0A0H2W8V3	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:a0a5p8yav7_yerpe(display_long)|uniprotkb:pelY(gene name)|psi-mi:pelY(display_short)|uniprotkb:YPO3994(locus name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865497|imex:IM-13779-7106	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010702(Periplasmic pectate lyase)|refseq:YP_002348864.1|refseq:WP_002209555.1|go:""GO:0016837""(carbon-oxygen lyase activity, acting on polysaccharides)|go:""GO:0042597""(periplasmic space)|go:""GO:0045490""(pectin catabolic process)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:TdSmcoWgW+r5eNyU5ieC4Vae68s632	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:AF05A324CD38C16A|rigid:rA7NZPqBTMq49pSR+DbC59z9WwM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARH3	uniprotkb:P17931	intact:EBI-2849426|uniprotkb:A0A384KLR8|uniprotkb:O68711|uniprotkb:Q74YV0|uniprotkb:A0A0H2W092|uniprotkb:A0A2U2GVE2	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:q7arh3_yerpe(display_long)|uniprotkb:tnpA(gene name)|psi-mi:tnpA(display_short)|uniprotkb:YPCD1.90c(locus name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865523|imex:IM-13779-7110	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_857769.1|interpro:IPR002513(Transposase, Tn3)|refseq:NP_395219.1|interpro:IPR025296|interpro:IPR047653|refseq:WP_002213256.1|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:00nBYkSaVEOjkb6Bm6Lk/llhQRc632	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:AFA7D64499C7EA09|rigid:PwC6C6w2bS0tFmoYplg9uTx+Ysc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A5P8YB39	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2865507|uniprotkb:Q74QR6|uniprotkb:A0A0H2W8K9|uniprotkb:Q7CFR3|uniprotkb:A0A384L492	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:a0a5p8yb39_yerpe(display_long)|uniprotkb:YPO4034(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865504|imex:IM-13779-7111	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR020449|interpro:IPR018062|interpro:IPR028082|interpro:IPR054031|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0006355""(regulation of DNA-templated transcription)|refseq:WP_002209588.1|refseq:YP_002348897.1|interpro:IPR046335|panther:PTHR30146(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:3yr8Qx0EzYHSLwmNTm0PNub82LI632	intact-crc:522FF58C5FD2BA3D|rigid:hK/skEacPMjAxds/eD2Vxew1LJY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A2U2GUX9	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2841416|uniprotkb:A0A0H2W940|uniprotkb:Q74PB0|uniprotkb:A0A384LLI5|uniprotkb:Q7CFN3|uniprotkb:A0A3N4BJ32	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:a0a2u2gux9_yerpe(display_long)|uniprotkb:YPO4108(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865516|imex:IM-13779-7107	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR023214|interpro:IPR041492|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002215575.1|refseq:YP_002348959.1|interpro:IPR023198|interpro:IPR036412|interpro:IPR051600"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:N4DmZVhdbeJX1EvnC462dwFiaNU632	intact-crc:BC6E043985500040|rigid:9fBEeOUD8CMBHnsyInNDOl+2jNw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ICC9	uniprotkb:Q8ZIC6	intact:EBI-2865533|uniprotkb:Q6ZTR1|ensembl:ENSP00000340434.3	intact:EBI-2860508|uniprotkb:Q8CZR0|uniprotkb:Q0WJ87	psi-mi:rtl6_human(display_long)|uniprotkb:RTL6(gene name)|psi-mi:RTL6(display_short)|uniprotkb:LDOC1L(gene name synonym)|uniprotkb:Leucine zipper protein down-regulated in cancer cells-like(gene name synonym)|uniprotkb:MAR6(gene name synonym)|uniprotkb:MART6(gene name synonym)|uniprotkb:Mammalian retrotransposon-derived protein 6(gene name synonym)|uniprotkb:Protein LDOC1L(gene name synonym)	psi-mi:uxac_yerpe(display_long)|uniprotkb:uxaC(gene name)|psi-mi:uxaC(display_short)|uniprotkb:Glucuronate isomerase(gene name synonym)|uniprotkb:Uronic isomerase(gene name synonym)|uniprotkb:YPO0579(locus name)|uniprotkb:y3600(locus name)|uniprotkb:YP_2899(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865530|imex:IM-13779-7108	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	ensembl:ENSG00000188636.4(gene)|ensembl:ENST00000341255.4(transcript)|interpro:IPR032549|refseq:NP_115663.2|panther:PTHR15503(orthology-group)	"interpro:IPR003766(Glucuronate isomerase)|refseq:WP_002210410.1|interpro:IPR032466|go:""GO:0008880""(glucuronate isomerase activity)|go:""GO:0019698""(D-galacturonate catabolic process)|go:""GO:0042840""(D-glucuronate catabolic process)|refseq:YP_002345651.1|panther:PTHR30068(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7o+PcSDyWEmgNTkzUTfk345q7ng9606	rogid:xvb/gj4dlbyJ5YEc5bnU6UL77to632	intact-crc:E14FBADB070C79FB|rigid:8H4Pjx4dpxvbN3TgGp0dS76vVFE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W4W6	uniprotkb:O95751	intact:EBI-2843661|uniprotkb:Q74TV2|uniprotkb:Q7CIL3|uniprotkb:A0A2S9PM22|uniprotkb:Q0WEU1	intact:EBI-740738|uniprotkb:Q6IAR6|ensembl:ENSP00000359557.2	psi-mi:a0a0h2w4w6_yerpe(display_long)|uniprotkb:YPO2225(locus name)|uniprotkb:lapB(gene name)|psi-mi:lapB(display_short)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865542|imex:IM-13779-7109	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR041166|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_002210615.1|go:""GO:0005506""(iron ion binding)|go:""GO:0008653""(lipopolysaccharide metabolic process)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0046890""(regulation of lipid biosynthetic process)|interpro:IPR030865|refseq:YP_002347197.1|interpro:IPR051012"	"refseq:NP_036449.1|ensembl:ENSG00000182195.9(gene)|ensembl:ENST00000370526.5(transcript)|go:""GO:0001893""(maternal placenta development)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0060137""(maternal process involved in parturition)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071225""(cellular response to muramyl dipeptide)|interpro:IPR032549|mint:O95751"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7cni0SRWd3fah/tNgRWzUoUBIN8632	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:8BF3C4179E93C5B0|rigid:uFQy3fpkHKtLYv2jEEWyyQQixB0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WG23	uniprotkb:P00338	intact:EBI-2865571|uniprotkb:Q74US4|uniprotkb:A0A0H2W4X1|uniprotkb:Q7CHV8|uniprotkb:A0A384KQ92	intact:EBI-372327|ensembl:ENSP00000395337.3|ensembl:ENSP00000445331.1|ensembl:ENSP00000499898.1|ensembl:ENSP00000499977.1|ensembl:ENSP00000500953.1|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819	psi-mi:q0wg23_yerpe(display_long)|uniprotkb:hpaX(gene name)|psi-mi:hpaX(display_short)|uniprotkb:YPO1768(locus name)	psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865568|imex:IM-13779-7113	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012707(4-hydroxyphenylacetate permease)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|refseq:WP_002211076.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:1900754""(4-hydroxyphenylacetate transport)|go:""GO:1901241""(4-hydroxyphenylacetate transmembrane transporter activity)|interpro:IPR036259|refseq:YP_002346765.1|panther:PTHR43791(orthology-group)"	"ensembl:ENSG00000134333.15(gene)|ensembl:ENSG00000288299.1(gene)|ensembl:ENST00000422447.8(transcript)|ensembl:ENST00000542179.1(transcript)|ensembl:ENST00000671981.1(transcript)|ensembl:ENST00000672405.1(transcript)|ensembl:ENST00000673204.1(transcript)|go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0021762""(substantia nigra development)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990204""(oxidoreductase complex)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P00338|rcsb pdb:1I10|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6Q13|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|rcsb pdb:7M2N|rcsb pdb:8FW6|rcsb pdb:9BK2|rcsb pdb:9BK3|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:NP_001128711.1|refseq:NP_001158886.1|refseq:NP_001158887.1|refseq:NP_001158888.1|refseq:NP_005557.1|efo:""Orphanet:284426""|panther:PTHR43128(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pkeFuahq4iOgbU/nZnL83wCcdE8632	rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606	intact-crc:01977FB57DD3760C|rigid:F7eJ8zkVvtHOR/7qPF7e0KtaP/I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00338	uniprotkb:Q0WDM7	intact:EBI-372327|ensembl:ENSP00000395337.3|ensembl:ENSP00000445331.1|ensembl:ENSP00000499898.1|ensembl:ENSP00000499977.1|ensembl:ENSP00000500953.1|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819	intact:EBI-2865556|uniprotkb:Q74SV0|uniprotkb:A0A0H2W728|uniprotkb:Q7CJS7|uniprotkb:A0A384KLT6|uniprotkb:A0A2U2H330	psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name)	psi-mi:q0wdm7_yerpe(display_long)|uniprotkb:YPO2662(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865561|imex:IM-13779-7114	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000134333.15(gene)|ensembl:ENSG00000288299.1(gene)|ensembl:ENST00000422447.8(transcript)|ensembl:ENST00000542179.1(transcript)|ensembl:ENST00000671981.1(transcript)|ensembl:ENST00000672405.1(transcript)|ensembl:ENST00000673204.1(transcript)|go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0016020""(membrane)|go:""GO:0021762""(substantia nigra development)|go:""GO:0042802""(identical protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990204""(oxidoreductase complex)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P00338|rcsb pdb:1I10|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6Q13|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|rcsb pdb:7M2N|rcsb pdb:8FW6|rcsb pdb:9BK2|rcsb pdb:9BK3|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:NP_001128711.1|refseq:NP_001158886.1|refseq:NP_001158887.1|refseq:NP_001158888.1|refseq:NP_005557.1|efo:""Orphanet:284426""|panther:PTHR43128(orthology-group)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_002212224.1|interpro:IPR050366|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|interpro:IPR035906|refseq:YP_002347611.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606	rogid:x/JVXiWDWI5MdiXlRSjFeq/82hs632	intact-crc:E67FECB57CB10A22|rigid:kMRtzJoPiy74W9gehsZrX7Bkhw4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13094	uniprotkb:A0A2U2H163	intact:EBI-346946|uniprotkb:Q53XV4|uniprotkb:A8KA25|ensembl:ENSP00000046794.5	intact:EBI-2849095|uniprotkb:Q74VM1|uniprotkb:Q0WH98|uniprotkb:Q7CHF6|uniprotkb:A0A384KHA9	psi-mi:lcp2_human(display_long)|uniprotkb:LCP2(gene name)|psi-mi:LCP2(display_short)|uniprotkb:SH2 domain-containing leukocyte protein of 76 kDa(gene name synonym)|uniprotkb:SLP-76 tyrosine phosphoprotein(gene name synonym)	psi-mi:a0a2u2h163_yerpe(display_long)|uniprotkb:YPO1315(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865593|imex:IM-13779-7116	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005556.1|dip:DIP-31812N|panther:PTHR14098(orthology-group)|ensembl:ENSG00000043462.13(gene)|ensembl:ENST00000046794.10(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006955""(immune response)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036398""(TCR signalosome)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045576""(mast cell activation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036860|interpro:IPR051751|mint:Q13094|rcsb pdb:1H3H|rcsb pdb:1YWO|rcsb pdb:2EAP|rcsb pdb:2ROR|rcsb pdb:6ZCJ|reactome:R-HSA-114604|reactome:R-HSA-202433|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809"	"interpro:IPR023214|interpro:IPR006385(HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial)|refseq:WP_002215448.1|go:""GO:0016787""(hydrolase activity)|interpro:IPR036412|refseq:YP_002346340.1|interpro:IPR050582|panther:PTHR43344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lZa+nAuqvGDrNe3Jhxn/JQaU5ug9606	rogid:CZMciP/S1SwtzGQyBQQdrmMpLg0632	intact-crc:8E6A1331C0767D7E|rigid:rgVdOaNMn/F8tqLd6DI3xthf3UU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43679	uniprotkb:A0A3N4BL48	intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772.5	intact:EBI-2840695|uniprotkb:Q74QY7|uniprotkb:A0A384KJ61|uniprotkb:Q0WA64|uniprotkb:Q7CFZ2	psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym)	psi-mi:a0a3n4bl48_yerpe(display_long)|uniprotkb:YPO3953(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865586|imex:IM-13779-7115	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744.13(gene)|ensembl:ENST00000304523.10(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001942""(hair follicle development)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0007399""(nervous system development)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0019899""(enzyme binding)|go:""GO:0030274""(LIM domain binding)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0031252""(cell leading edge)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0043549""(regulation of kinase activity)|go:""GO:0044089""(positive regulation of cellular component biogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR029005|interpro:IPR041363|mint:O43679|panther:PTHR10378(orthology-group)"	"interpro:IPR006001(Carbohydrate kinase, thermoresistant glucokinase)|refseq:YP_002348824.1|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0046177""(obsolete D-gluconate catabolic process)|go:""GO:0046316""(gluconokinase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR031322|refseq:WP_002209512.1|panther:PTHR43442(orthology-group)"	"psi-mi:""MI:0469""(intact)"	crc64:E86387BA027F383A	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606	rogid:jDPHbir+9JsfYMNOL0KeIOpfO6I632	intact-crc:7954E5AE1D5ADAC9|rigid:W/lQ5HCxFuIk+PJH+ywRq1UIOdk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PDF6	uniprotkb:P07195	intact:EBI-2856702|uniprotkb:Q74UZ3|uniprotkb:Q7CI04|uniprotkb:A0A0H2W3V4	intact:EBI-358748|ensembl:ENSP00000229319.1|ensembl:ENSP00000379386.1	psi-mi:a0a380pdf6_yerpe(display_long)|uniprotkb:yecS(gene name)|psi-mi:yecS(display_short)|uniprotkb:YPO1847(locus name)	psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865549|imex:IM-13779-7112	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_002211158.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015184""(L-cystine transmembrane transporter activity)|go:""GO:0015811""(L-cystine transport)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|interpro:IPR035906|interpro:IPR043429|refseq:YP_002346841.1|panther:PTHR30614(orthology-group)"	"ensembl:ENSG00000111716.14(gene)|ensembl:ENST00000350669.5(transcript)|ensembl:ENST00000396076.5(transcript)|go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0019674""(NAD metabolic process)|go:""GO:0019900""(kinase binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045121""(membrane raft)|go:""GO:0051287""(NAD binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990204""(oxidoreductase complex)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|rcsb pdb:7DBJ|rcsb pdb:7DBK|rcsb pdb:8QDE|reactome:R-HSA-70268|refseq:NP_001167568.1|refseq:NP_001302466.1|refseq:NP_002291.1|efo:""Orphanet:284435""|panther:PTHR43128(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pJ27jWvWt/SRd2N+cRvIV71qr60632	rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606	intact-crc:B0AF6052534F793F|rigid:mW0r5fTTh7rBwA7Y81icctJI1AI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06239	uniprotkb:A0A2U2GZS8	intact:EBI-1348|uniprotkb:P07100|uniprotkb:Q12850|uniprotkb:Q13152|uniprotkb:Q5TDH8|uniprotkb:Q5TDH9|uniprotkb:Q96DW4|uniprotkb:Q9NYT8|uniprotkb:Q7RTZ3|uniprotkb:D3DPP8|ensembl:ENSP00000337825.5	intact:EBI-2865614|uniprotkb:Q0WGP1|uniprotkb:Q3V8F7|uniprotkb:A0A384LMB2	psi-mi:lck_human(display_long)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:a0a2u2gzs8_yerpe(display_long)|uniprotkb:alcB(gene name)|psi-mi:alcB(display_short)|uniprotkb:YPO1531(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865618|imex:IM-13779-7120	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-553N|panther:PTHR24418(orthology-group)|efo:""Orphanet:280142""|ensembl:ENSG00000182866.18(gene)|ensembl:ENST00000336890.10(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001772""(immunological synapse)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030168""(platelet activation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0031295""(T cell costimulation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0042110""(T cell activation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051117""(ATPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051249""(regulation of lymphocyte activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1903039""(positive regulation of leukocyte cell-cell adhesion)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P06239|rcsb pdb:1BHF|rcsb pdb:1BHH|rcsb pdb:1CWD|rcsb pdb:1CWE|rcsb pdb:1FBZ|rcsb pdb:1H92|rcsb pdb:1IJR|rcsb pdb:1KIK|rcsb pdb:1LCJ|rcsb pdb:1LCK|rcsb pdb:1LKK|rcsb pdb:1LKL|rcsb pdb:1Q68|rcsb pdb:1Q69|rcsb pdb:1QPC|rcsb pdb:1QPD|rcsb pdb:1QPE|rcsb pdb:1QPJ|rcsb pdb:1X27|rcsb pdb:2IIM|rcsb pdb:2OF2|rcsb pdb:2OF4|rcsb pdb:2OFU|rcsb pdb:2OFV|rcsb pdb:2OG8|rcsb pdb:2PL0|rcsb pdb:2ZM1|rcsb pdb:2ZM4|rcsb pdb:2ZYB|rcsb pdb:3AC1|rcsb pdb:3AC2|rcsb pdb:3AC3|rcsb pdb:3AC4|rcsb pdb:3AC5|rcsb pdb:3AC8|rcsb pdb:3ACJ|rcsb pdb:3ACK|rcsb pdb:3AD4|rcsb pdb:3AD5|rcsb pdb:3AD6|rcsb pdb:3B2W|rcsb pdb:3BRH|rcsb pdb:3BYM|rcsb pdb:3BYO|rcsb pdb:3BYS|rcsb pdb:3BYU|rcsb pdb:3KMM|rcsb pdb:3KXZ|rcsb pdb:3LCK|rcsb pdb:3MPM|rcsb pdb:4C3F|rcsb pdb:4D8K|rcsb pdb:5MTM|rcsb pdb:5MTN|rcsb pdb:6H6A|rcsb pdb:6PDJ|rcsb pdb:8X2P|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-167590|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-6811558|reactome:R-HSA-9013407|reactome:R-HSA-9020558|reactome:R-HSA-9670439|reactome:R-HSA-9706374|refseq:NP_001036236.1|refseq:NP_005347.3"	"interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR019432|go:""GO:0016410""(N-acyltransferase activity)|go:""GO:0019290""(siderophore biosynthetic process)|refseq:YP_002346547.1|panther:PTHR31438(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/26	rogid:AIdRYIcSNXmD2ovQiEn9N4CWr/M9606	rogid:qBu200QkaysRJzhM/COXziUdEgo632	intact-crc:994B18A748ECD598|rigid:WH+ob4XvyWSsHn5lQvJ0/om6WoY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06239	uniprotkb:Q8ZJ74	intact:EBI-1348|uniprotkb:P07100|uniprotkb:Q12850|uniprotkb:Q13152|uniprotkb:Q5TDH8|uniprotkb:Q5TDH9|uniprotkb:Q96DW4|uniprotkb:Q9NYT8|uniprotkb:Q7RTZ3|uniprotkb:D3DPP8|ensembl:ENSP00000337825.5	intact:EBI-2861133|uniprotkb:Q0WK60	psi-mi:lck_human(display_long)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:aroe_yerpe(display_long)|uniprotkb:aroE(gene name)|psi-mi:aroE(display_short)|uniprotkb:YPO0246(locus name)|uniprotkb:y4028(locus name)|uniprotkb:YP_0245(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865632|imex:IM-13779-7119	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-553N|panther:PTHR24418(orthology-group)|efo:""Orphanet:280142""|ensembl:ENSG00000182866.18(gene)|ensembl:ENST00000336890.10(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001772""(immunological synapse)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030168""(platelet activation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0031295""(T cell costimulation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0042110""(T cell activation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051117""(ATPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051249""(regulation of lymphocyte activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1903039""(positive regulation of leukocyte cell-cell adhesion)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P06239|rcsb pdb:1BHF|rcsb pdb:1BHH|rcsb pdb:1CWD|rcsb pdb:1CWE|rcsb pdb:1FBZ|rcsb pdb:1H92|rcsb pdb:1IJR|rcsb pdb:1KIK|rcsb pdb:1LCJ|rcsb pdb:1LCK|rcsb pdb:1LKK|rcsb pdb:1LKL|rcsb pdb:1Q68|rcsb pdb:1Q69|rcsb pdb:1QPC|rcsb pdb:1QPD|rcsb pdb:1QPE|rcsb pdb:1QPJ|rcsb pdb:1X27|rcsb pdb:2IIM|rcsb pdb:2OF2|rcsb pdb:2OF4|rcsb pdb:2OFU|rcsb pdb:2OFV|rcsb pdb:2OG8|rcsb pdb:2PL0|rcsb pdb:2ZM1|rcsb pdb:2ZM4|rcsb pdb:2ZYB|rcsb pdb:3AC1|rcsb pdb:3AC2|rcsb pdb:3AC3|rcsb pdb:3AC4|rcsb pdb:3AC5|rcsb pdb:3AC8|rcsb pdb:3ACJ|rcsb pdb:3ACK|rcsb pdb:3AD4|rcsb pdb:3AD5|rcsb pdb:3AD6|rcsb pdb:3B2W|rcsb pdb:3BRH|rcsb pdb:3BYM|rcsb pdb:3BYO|rcsb pdb:3BYS|rcsb pdb:3BYU|rcsb pdb:3KMM|rcsb pdb:3KXZ|rcsb pdb:3LCK|rcsb pdb:3MPM|rcsb pdb:4C3F|rcsb pdb:4D8K|rcsb pdb:5MTM|rcsb pdb:5MTN|rcsb pdb:6H6A|rcsb pdb:6PDJ|rcsb pdb:8X2P|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-167590|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-6811558|reactome:R-HSA-9013407|reactome:R-HSA-9020558|reactome:R-HSA-9670439|reactome:R-HSA-9706374|refseq:NP_001036236.1|refseq:NP_005347.3"	"interpro:IPR011342(Quinate/shikimate 5-dehydrogenase)|interpro:IPR013708(Shikimate dehydrogenase substrate binding, N-terminal)|interpro:IPR022893|interpro:IPR006151(Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase)|refseq:WP_002209026.1|go:""GO:0004764""(""shikimate 3-dehydrogenase (NADP+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0009073""(aromatic amino acid family biosynthetic process)|go:""GO:0009423""(chorismate biosynthetic process)|go:""GO:0019632""(shikimate metabolic process)|go:""GO:0050661""(NADP binding)|interpro:IPR036291|interpro:IPR041121|refseq:YP_002345328.1|interpro:IPR046346|panther:PTHR21089(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/26	rogid:AIdRYIcSNXmD2ovQiEn9N4CWr/M9606	rogid:dRYrxoQeMbXrptePRIuZexxnfl8632	intact-crc:4B173503A390C068|rigid:FTXtwBnZQwn/sppyLy5lZ9mP8VI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YCS1	uniprotkb:P06239	intact:EBI-2845539|uniprotkb:Q74X99|uniprotkb:Q7CKL1|uniprotkb:A0A0H2W363	intact:EBI-1348|uniprotkb:P07100|uniprotkb:Q12850|uniprotkb:Q13152|uniprotkb:Q5TDH8|uniprotkb:Q5TDH9|uniprotkb:Q96DW4|uniprotkb:Q9NYT8|uniprotkb:Q7RTZ3|uniprotkb:D3DPP8|ensembl:ENSP00000337825.5	psi-mi:a0a5p8ycs1_yerpe(display_long)|uniprotkb:fklB(gene name)|psi-mi:fklB(display_short)|uniprotkb:YPO3532(locus name)	psi-mi:lck_human(display_long)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865607|imex:IM-13779-7117	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR000774(Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal)|refseq:WP_002228198.1|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0006457""(protein folding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR036944|refseq:YP_002348421.1|interpro:IPR046357|panther:PTHR43811(orthology-group)"	"dip:DIP-553N|panther:PTHR24418(orthology-group)|efo:""Orphanet:280142""|ensembl:ENSG00000182866.18(gene)|ensembl:ENST00000336890.10(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001772""(immunological synapse)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030168""(platelet activation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0031295""(T cell costimulation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0042110""(T cell activation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051117""(ATPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051249""(regulation of lymphocyte activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1903039""(positive regulation of leukocyte cell-cell adhesion)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P06239|rcsb pdb:1BHF|rcsb pdb:1BHH|rcsb pdb:1CWD|rcsb pdb:1CWE|rcsb pdb:1FBZ|rcsb pdb:1H92|rcsb pdb:1IJR|rcsb pdb:1KIK|rcsb pdb:1LCJ|rcsb pdb:1LCK|rcsb pdb:1LKK|rcsb pdb:1LKL|rcsb pdb:1Q68|rcsb pdb:1Q69|rcsb pdb:1QPC|rcsb pdb:1QPD|rcsb pdb:1QPE|rcsb pdb:1QPJ|rcsb pdb:1X27|rcsb pdb:2IIM|rcsb pdb:2OF2|rcsb pdb:2OF4|rcsb pdb:2OFU|rcsb pdb:2OFV|rcsb pdb:2OG8|rcsb pdb:2PL0|rcsb pdb:2ZM1|rcsb pdb:2ZM4|rcsb pdb:2ZYB|rcsb pdb:3AC1|rcsb pdb:3AC2|rcsb pdb:3AC3|rcsb pdb:3AC4|rcsb pdb:3AC5|rcsb pdb:3AC8|rcsb pdb:3ACJ|rcsb pdb:3ACK|rcsb pdb:3AD4|rcsb pdb:3AD5|rcsb pdb:3AD6|rcsb pdb:3B2W|rcsb pdb:3BRH|rcsb pdb:3BYM|rcsb pdb:3BYO|rcsb pdb:3BYS|rcsb pdb:3BYU|rcsb pdb:3KMM|rcsb pdb:3KXZ|rcsb pdb:3LCK|rcsb pdb:3MPM|rcsb pdb:4C3F|rcsb pdb:4D8K|rcsb pdb:5MTM|rcsb pdb:5MTN|rcsb pdb:6H6A|rcsb pdb:6PDJ|rcsb pdb:8X2P|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-167590|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-6811558|reactome:R-HSA-9013407|reactome:R-HSA-9020558|reactome:R-HSA-9670439|reactome:R-HSA-9706374|refseq:NP_001036236.1|refseq:NP_005347.3"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/26	rogid:3Rld9RV594sVyXzqp5V7qbiNN1s632	rogid:AIdRYIcSNXmD2ovQiEn9N4CWr/M9606	intact-crc:68D1B32CC2207398|rigid:+3gvoWKVlIMNSrPeW08kILb/mbA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06239	uniprotkb:Q8ZDA6	intact:EBI-1348|uniprotkb:P07100|uniprotkb:Q12850|uniprotkb:Q13152|uniprotkb:Q5TDH8|uniprotkb:Q5TDH9|uniprotkb:Q96DW4|uniprotkb:Q9NYT8|uniprotkb:Q7RTZ3|uniprotkb:D3DPP8|ensembl:ENSP00000337825.5	intact:EBI-2843773|uniprotkb:Q0WDK8	psi-mi:lck_human(display_long)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:chbg_yerpe(display_long)|uniprotkb:chbG(gene name)|psi-mi:chbG(display_short)|uniprotkb:Chitin disaccharide deacetylase(gene name synonym)|uniprotkb:Chitobiose deacetylase(gene name synonym)|uniprotkb:Chitobiose-6P deacetylase(gene name synonym)|uniprotkb:Chitotriose deacetylase(gene name synonym)|uniprotkb:Chitotriose-6P deacetylase(gene name synonym)|uniprotkb:YPO2682(locus name)|uniprotkb:YP_2484(locus name)|uniprotkb:y1255(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865625|imex:IM-13779-7118	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-553N|panther:PTHR24418(orthology-group)|efo:""Orphanet:280142""|ensembl:ENSG00000182866.18(gene)|ensembl:ENST00000336890.10(transcript)|go:""GO:0000242""(pericentriolar material)|go:""GO:0001772""(immunological synapse)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0004722""(protein serine/threonine phosphatase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016004""(phospholipase activator activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030168""(platelet activation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0031295""(T cell costimulation)|go:""GO:0034116""(positive regulation of heterotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0042110""(T cell activation)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043274""(phospholipase binding)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045121""(membrane raft)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0050862""(positive regulation of T cell receptor signaling pathway)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051117""(ATPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051249""(regulation of lymphocyte activation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0160162""(CD27 signaling pathway)|go:""GO:1903039""(positive regulation of leukocyte cell-cell adhesion)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|interpro:IPR050198|mint:P06239|rcsb pdb:1BHF|rcsb pdb:1BHH|rcsb pdb:1CWD|rcsb pdb:1CWE|rcsb pdb:1FBZ|rcsb pdb:1H92|rcsb pdb:1IJR|rcsb pdb:1KIK|rcsb pdb:1LCJ|rcsb pdb:1LCK|rcsb pdb:1LKK|rcsb pdb:1LKL|rcsb pdb:1Q68|rcsb pdb:1Q69|rcsb pdb:1QPC|rcsb pdb:1QPD|rcsb pdb:1QPE|rcsb pdb:1QPJ|rcsb pdb:1X27|rcsb pdb:2IIM|rcsb pdb:2OF2|rcsb pdb:2OF4|rcsb pdb:2OFU|rcsb pdb:2OFV|rcsb pdb:2OG8|rcsb pdb:2PL0|rcsb pdb:2ZM1|rcsb pdb:2ZM4|rcsb pdb:2ZYB|rcsb pdb:3AC1|rcsb pdb:3AC2|rcsb pdb:3AC3|rcsb pdb:3AC4|rcsb pdb:3AC5|rcsb pdb:3AC8|rcsb pdb:3ACJ|rcsb pdb:3ACK|rcsb pdb:3AD4|rcsb pdb:3AD5|rcsb pdb:3AD6|rcsb pdb:3B2W|rcsb pdb:3BRH|rcsb pdb:3BYM|rcsb pdb:3BYO|rcsb pdb:3BYS|rcsb pdb:3BYU|rcsb pdb:3KMM|rcsb pdb:3KXZ|rcsb pdb:3LCK|rcsb pdb:3MPM|rcsb pdb:4C3F|rcsb pdb:4D8K|rcsb pdb:5MTM|rcsb pdb:5MTN|rcsb pdb:6H6A|rcsb pdb:6PDJ|rcsb pdb:8X2P|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-167590|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-6811558|reactome:R-HSA-9013407|reactome:R-HSA-9020558|reactome:R-HSA-9670439|reactome:R-HSA-9706374|refseq:NP_001036236.1|refseq:NP_005347.3"	"interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR006879(YdjC-like protein)|interpro:IPR022948|go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0005737""(cytoplasm)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0019213""(deacetylase activity)|go:""GO:0036311""(chitin disaccharide deacetylase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0052777""(diacetylchitobiose catabolic process)|refseq:WP_002212244.1|refseq:YP_002347630.1|panther:PTHR31609(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/26	rogid:AIdRYIcSNXmD2ovQiEn9N4CWr/M9606	rogid:pYqUZfBmwRlqczCS0iM02q3LMNo632	intact-crc:F9459B03A33A079D|rigid:SmfcAUeSv4tsqHTSuw97avAjjEM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UIC8	uniprotkb:P58526	intact:EBI-747632|uniprotkb:A6NL89|uniprotkb:Q53FC5|uniprotkb:Q96CI5|uniprotkb:Q9NTG4|uniprotkb:Q9Y378|uniprotkb:Q9H6I9|uniprotkb:A8K770|ensembl:ENSP00000382021.3	intact:EBI-2851618|uniprotkb:Q0WE76	psi-mi:lcmt1_human(display_long)|uniprotkb:Protein-leucine O-methyltransferase(gene name synonym)|uniprotkb:LCMT1(gene name)|psi-mi:LCMT1(display_short)|uniprotkb:LCMT(gene name synonym)|uniprotkb:[Phosphatase 2A protein]-leucine-carboxy methyltransferase 1(gene name synonym)|uniprotkb:CGI-68(orf name)	psi-mi:mtox_yerpe(display_long)|uniprotkb:solA(gene name)|psi-mi:solA(display_short)|uniprotkb:YPO2448(locus name)|uniprotkb:y1742(locus name)|uniprotkb:YP_2268(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865600|imex:IM-13779-7121	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001027563.1|refseq:NP_057393.2|ensembl:ENSG00000205629.12(gene)|ensembl:ENST00000399069.8(transcript)|go:""GO:0000086""(G2/M transition of mitotic cell cycle)|go:""GO:0003880""(protein C-terminal carboxyl O-methyltransferase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006479""(protein methylation)|go:""GO:0006481""(C-terminal protein methylation)|go:""GO:0008757""(S-adenosylmethionine-dependent methyltransferase activity)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0018423""(protein C-terminal leucine carboxyl O-methyltransferase activity)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0036211""(protein modification process)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0090266""(regulation of mitotic cell cycle spindle assembly checkpoint)|interpro:IPR007213(Leucine carboxyl methyltransferase)|interpro:IPR016651(Leucine carboxyl methyltransferase, LCTM1 1)|interpro:IPR029063|mint:Q9UIC8|rcsb pdb:3IEI|rcsb pdb:3O7W|rcsb pdb:3P71|reactome:R-HSA-69273|refseq:XP_011544166.1|panther:PTHR13600(orthology-group)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR023493|refseq:WP_002211850.1|go:""GO:0005829""(cytosol)|go:""GO:0008115""(sarcosine oxidase activity)|go:""GO:0050131""(N-methyl-L-amino-acid oxidase activity)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|refseq:YP_002347412.1|interpro:IPR045170|panther:PTHR10961(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YNCPaQQoOXhlXr9kDqjt9XYjD9w9606	rogid:CVPINp8wGJnyzKPXSUk8Tm4az0w632	intact-crc:64BE6BD0DF2B0901|rigid:0VGdPiKcMx8RmlTfysKUJIIR/FE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96G23	uniprotkb:Q8D194	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688.6|ensembl:ENSP00000357950.5	intact:EBI-2847851|uniprotkb:Q74XR4	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	psi-mi:q8d194_yerpe(display_long)|uniprotkb:dAK1_1(gene name)|psi-mi:dAK1_1(display_short)|uniprotkb:YP_0337(locus name)|uniprotkb:y0840(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865639|imex:IM-13779-7122	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418.20(gene)|ensembl:ENST00000271688.10(transcript)|ensembl:ENST00000368954.10(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016020""(membrane)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0030148""(sphingolipid biosynthetic process)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0046513""(ceramide biosynthetic process)|go:""GO:0048681""(negative regulation of axon regeneration)|go:""GO:0050291""(sphingosine N-acyltransferase activity)|go:""GO:1900148""(negative regulation of Schwann cell migration)|go:""GO:1905045""(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|panther:PTHR12560(orthology-group)"	"interpro:IPR004006(Dak kinase)|go:""GO:0004371""(glycerone kinase activity)|go:""GO:0006071""(glycerol metabolic process)|interpro:IPR050861"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	rogid:PGSwAYXIFUUnJmzpLaHT1vlvQxc632	intact-crc:EB4251BAD1F13843|rigid:s6EvE4X5xh9iJSiOgoYaC4XLvYU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13571	uniprotkb:Q8D0D4	intact:EBI-2865663|uniprotkb:Q14698|uniprotkb:Q13240|uniprotkb:Q3KP54|ensembl:ENSP00000294507.3	intact:EBI-2847212	psi-mi:lapm5_human(display_long)|uniprotkb:LAPTM5(gene name)|psi-mi:LAPTM5(display_short)|uniprotkb:KIAA0085(gene name synonym)|uniprotkb:Lysosomal-associated multitransmembrane protein 5(gene name synonym)|uniprotkb:Retinoic acid-inducible E3 protein(gene name synonym)	psi-mi:q8d0d4_yerpe(display_long)|uniprotkb:hmsH(gene name)|psi-mi:hmsH(display_short)|uniprotkb:y2359(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865660|imex:IM-13779-7123	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006753.1|ensembl:ENSG00000162511.8(gene)|ensembl:ENST00000294507.4(transcript)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002720""(positive regulation of cytokine production involved in immune response)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0012502""(induction of programmed cell death)|go:""GO:0030133""(transport vesicle)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050868""(negative regulation of T cell activation)|go:""GO:0050869""(negative regulation of B cell activation)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097214""(positive regulation of lysosomal membrane permeability)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1904093""(negative regulation of autophagic cell death)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR004687(Golgi 4-transmembrane spanning transporter)|interpro:IPR018396|interpro:IPR051115|mint:Q13571|panther:PTHR12479(orthology-group)"	"interpro:IPR023870|interpro:IPR011990(Tetratricopeptide-like helical)|go:""GO:1901515""(poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity)|interpro:IPR049003"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oNH512GKUe4Y4qwd20918LMQzPE9606	rogid:oBs/IRM9/gKecuXNw9IoCZLu4Vw632	intact-crc:4856FD743E36D979|rigid:dpIIYbkEb+7YMf5V8Ew6zhpE+Ng	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q4G0J3	uniprotkb:Q0WGQ5	intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-25601393|intact:EBI-2560173|ensembl:ENSP00000344950.5|ensembl:ENSP00000421541.2|ensembl:ENSP00000422626.2|ensembl:ENSP00000499190.1|ensembl:ENSP00000511572.1	intact:EBI-2853517|uniprotkb:Q74VA6|uniprotkb:Q7CHR0	psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name)	psi-mi:q0wgq5_yerpe(display_long)|uniprotkb:YPO1517(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865646|imex:IM-13779-7124	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000174720.18(gene)|ensembl:ENST00000344442.10(transcript)|ensembl:ENST00000505034.6(transcript)|ensembl:ENST00000509061.5(transcript)|ensembl:ENST00000651579.1(transcript)|ensembl:ENST00000694894.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000494""(""box C/D sno(s)RNA 3'-end processing"")|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008380""(RNA splicing)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0097322""(7SK snRNA binding)|go:""GO:0120259""(7SK snRNP)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1905382""(positive regulation of snRNA transcription by RNA polymerase II)|go:""GO:1990438""(U6 2'-O-snRNA methylation)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12|rcsb pdb:7SLP|rcsb pdb:7SLQ|refseq:NP_001253968.1|refseq:NP_056269.1|refseq:NP_057732.2|dip:DIP-47624N|efo:""Orphanet:319671""|panther:PTHR22792(orthology-group)"	"interpro:IPR050555|interpro:IPR025997|interpro:IPR028082|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:YP_002346533.1|panther:PTHR30036(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606	rogid:qnuiW6B7FZ3gckfa7i2/HzKZAI8632	intact-crc:FE5CEA2F9E09B3A6|rigid:cM8bIxo2f8S09JSrA8SdsMH16iY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBN6	uniprotkb:Q4G0J3	intact:EBI-2845174|uniprotkb:Q0WBS4|uniprotkb:Q8D198|uniprotkb:Q74XS5	intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-25601393|intact:EBI-2560173|ensembl:ENSP00000344950.5|ensembl:ENSP00000421541.2|ensembl:ENSP00000422626.2|ensembl:ENSP00000499190.1|ensembl:ENSP00000511572.1	psi-mi:cysj_yerpe(display_long)|uniprotkb:cysJ(gene name)|psi-mi:cysJ(display_short)|uniprotkb:YPO3372(locus name)|uniprotkb:y0818(locus name)|uniprotkb:YP_0314(locus name)	psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865653|imex:IM-13779-7125	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010199(Sulphite reductase [NADPH] flavoprotein, alpha chain)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR017927|interpro:IPR001094(Flavodoxin-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR017938|interpro:IPR039261|interpro:IPR029039|interpro:IPR029758|refseq:WP_002209381.1|go:""GO:0000103""(sulfate assimilation)|go:""GO:0004783""(""sulfite reductase (NADPH) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0010181""(FMN binding)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0019344""(cysteine biosynthetic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070814""(hydrogen sulfide biosynthetic process)|interpro:IPR023173|refseq:YP_002348264.1|panther:PTHR19384(orthology-group)"	"ensembl:ENSG00000174720.18(gene)|ensembl:ENST00000344442.10(transcript)|ensembl:ENST00000505034.6(transcript)|ensembl:ENST00000509061.5(transcript)|ensembl:ENST00000651579.1(transcript)|ensembl:ENST00000694894.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000494""(""box C/D sno(s)RNA 3'-end processing"")|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008380""(RNA splicing)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0097322""(7SK snRNA binding)|go:""GO:0120259""(7SK snRNP)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1905382""(positive regulation of snRNA transcription by RNA polymerase II)|go:""GO:1990438""(U6 2'-O-snRNA methylation)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12|rcsb pdb:7SLP|rcsb pdb:7SLQ|refseq:NP_001253968.1|refseq:NP_056269.1|refseq:NP_057732.2|dip:DIP-47624N|efo:""Orphanet:319671""|panther:PTHR22792(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:/eQRgxmu+tsNIMHFJ+J0UIYifNc632	rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606	intact-crc:AAC89AF916EA0DF1|rigid:QUVWwUMt9dibdYhHOzO8uetf/ws	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14160	uniprotkb:A0A5P8YC43	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000349486.2|ensembl:ENSP00000484041.1	intact:EBI-2865688|uniprotkb:Q74RD2|uniprotkb:Q0WA94|uniprotkb:Q7CL14|uniprotkb:A0A384L6L5|uniprotkb:A0A2U2GZM6	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:a0a5p8yc43_yerpe(display_long)|uniprotkb:YPO3919(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865693|imex:IM-13779-7127	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056171.3|refseq:NP_874365.3|ensembl:ENSG00000180900.20(gene)|ensembl:ENSG00000274287.4(gene)|ensembl:ENST00000356994.7(transcript)|ensembl:ENST00000612204.4(transcript)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001843""(neural tube closure)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016080""(synaptic vesicle targeting)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0034750""(Scrib-APC-beta-catenin complex)|go:""GO:0035089""(establishment of apical/basal cell polarity)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042060""(wound healing)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043615""(astrocyte cell migration)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060561""(apoptotic process involved in morphogenesis)|go:""GO:0060603""(mammary gland duct morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098793""(presynapse)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098968""(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099147""(extrinsic component of postsynaptic density membrane)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|interpro:IPR050614|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|rcsb pdb:7QRS|rcsb pdb:7QRT|rcsb pdb:7QS8|rcsb pdb:7QS9|rcsb pdb:7QSA|rcsb pdb:7QSB|rcsb pdb:7QTO|rcsb pdb:7QTP|rcsb pdb:7QTU|rcsb pdb:8B82|rcsb pdb:8B87|rcsb pdb:8B8O|rcsb pdb:8B9T|rcsb pdb:8BIA|rcsb pdb:8BJ0|rcsb pdb:8CD3|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270|dip:DIP-31259N|panther:PTHR23119(orthology-group)"	"interpro:IPR010129(Type I secretion membrane fusion protein, HlyD)|interpro:IPR006144(Secretion protein HlyD, conserved site)|refseq:WP_002209482.1|interpro:IPR050739|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|interpro:IPR039562|refseq:YP_002348794.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:xHNrql5wX2JZV+9YxFGM7gm1/CY9606	rogid:qBRVC7K3Nzu9PsYbqgygKoEROUQ632	intact-crc:755A358226EEACE3|rigid:MBOh+oUmB+nQsZ0OizeUwUZDGLM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZQ2	uniprotkb:Q96RT1	intact:EBI-2865703|uniprotkb:Q74Q64	intact:EBI-993903|uniprotkb:Q86W38|uniprotkb:Q9NR18|uniprotkb:Q9NW48|uniprotkb:Q9ULJ5|uniprotkb:A0AVR1|uniprotkb:B4E3F1|uniprotkb:B7ZLV9|uniprotkb:E9PCR8|uniprotkb:Q1RMD0|uniprotkb:E7EQW9|ensembl:ENSP00000284037.4	psi-mi:q8czq2_yerpe(display_long)|uniprotkb:leuO(gene name)|psi-mi:leuO(display_short)|uniprotkb:YP_3643(locus name)|uniprotkb:y3642(locus name)	psi-mi:erbin_human(display_long)|uniprotkb:ERBIN(gene name)|psi-mi:ERBIN(display_short)|uniprotkb:Densin-180-like protein(gene name synonym)|uniprotkb:ERBB2IP(gene name synonym)|uniprotkb:Erbb2-interacting protein(gene name synonym)|uniprotkb:KIAA1225(gene name synonym)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Protein LAP2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865700|imex:IM-13779-7128	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|interpro:IPR050389|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390"	"efo:""Orphanet:656912""|ensembl:ENSG00000112851.16(gene)|ensembl:ENST00000284037.10(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005176""(ErbB-2 class receptor binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005604""(basement membrane)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030054""(cell junction)|go:""GO:0030056""(hemidesmosome)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0045175""(basal protein localization)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0070433""(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071638""(negative regulation of monocyte chemotactic protein-1 production)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099572""(postsynaptic specialization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|interpro:IPR050614|mint:Q96RT1|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1N7T|rcsb pdb:2H3L|rcsb pdb:2QBW|rcsb pdb:3CH8|rcsb pdb:6Q0M|rcsb pdb:6Q0N|rcsb pdb:6Q0U|rcsb pdb:6UBH|rcsb pdb:7LUL|reactome:R-HSA-1227986|reactome:R-HSA-8863795|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|refseq:NP_001006600.1|refseq:NP_001240626.1|refseq:NP_001240627.1|refseq:NP_001240628.1|refseq:NP_001240630.1|refseq:NP_061165.1|panther:PTHR45752(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:datIr1mDbwLwjR7PvLIkNLV9+go632	rogid:kITHWAgafb7t7RFgzs5ff7XCL3Y9606	intact-crc:9D41251D35626935|rigid:9RlyAjHQYSXoSam4O4pePy97b40	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZES0	uniprotkb:P11279	intact:EBI-2845458|uniprotkb:Q0WF73	intact:EBI-2805407|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40|ensembl:ENSP00000333298.4|uniprotkb:B4DWL3	psi-mi:y2083_yerpe(display_long)|uniprotkb:YPO2083(locus name)|uniprotkb:y2228(locus name)|uniprotkb:YP_1926(locus name)	psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865712|imex:IM-13779-7130	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008228(Uncharacterised conserved protein UCP006173)|interpro:IPR005358(Protein of unknown function UPF0153)|refseq:WP_002211739.1|refseq:YP_002347065.1|panther:PTHR37421(orthology-group)	"refseq:NP_005552.3|ensembl:ENSG00000185896.11(gene)|ensembl:ENST00000332556.5(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0001618""(virus receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0044754""(autolysosome)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0061474""(phagolysosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072594""(establishment of protein localization to organelle)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0140507""(granzyme-mediated programmed cell death signaling pathway)|go:""GO:1902513""(regulation of organelle transport along microtubule)|interpro:IPR002000(""Lysosome-associated membrane glycoprotein (Lamp)/CD68"")|interpro:IPR018134|interpro:IPR048524|interpro:IPR048528|mint:P11279|rcsb pdb:8ATH|rcsb pdb:8FY5|rcsb pdb:8FYF|reactome:R-HSA-6798695|dip:DIP-44670N|panther:PTHR11506(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:p1yW4rWt+CvstvpxbwtZ4Y1jXAU632	rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606	intact-crc:C4F235E32A1CEFF5|rigid:rTzbnzYQFQY3CfhJQgkYapy1YPU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14160	uniprotkb:Q8CKB2	intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000349486.2|ensembl:ENSP00000484041.1	intact:EBI-2857486	psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym)	psi-mi:q8ckb2_yerpe(display_long)|uniprotkb:y3797(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865681|imex:IM-13779-7129	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056171.3|refseq:NP_874365.3|ensembl:ENSG00000180900.20(gene)|ensembl:ENSG00000274287.4(gene)|ensembl:ENST00000356994.7(transcript)|ensembl:ENST00000612204.4(transcript)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001843""(neural tube closure)|go:""GO:0001921""(positive regulation of receptor recycling)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016080""(synaptic vesicle targeting)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021747""(cochlear nucleus development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030859""(polarized epithelial cell differentiation)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0034750""(Scrib-APC-beta-catenin complex)|go:""GO:0035089""(establishment of apical/basal cell polarity)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042060""(wound healing)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043615""(astrocyte cell migration)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045197""(establishment or maintenance of epithelial cell apical/basal polarity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0046007""(negative regulation of activated T cell proliferation)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0060088""(auditory receptor cell stereocilium organization)|go:""GO:0060561""(apoptotic process involved in morphogenesis)|go:""GO:0060603""(mammary gland duct morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098793""(presynapse)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098968""(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099147""(extrinsic component of postsynaptic density membrane)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|interpro:IPR050614|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|rcsb pdb:7QRS|rcsb pdb:7QRT|rcsb pdb:7QS8|rcsb pdb:7QS9|rcsb pdb:7QSA|rcsb pdb:7QSB|rcsb pdb:7QTO|rcsb pdb:7QTP|rcsb pdb:7QTU|rcsb pdb:8B82|rcsb pdb:8B87|rcsb pdb:8B8O|rcsb pdb:8B9T|rcsb pdb:8BIA|rcsb pdb:8BJ0|rcsb pdb:8CD3|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270|dip:DIP-31259N|panther:PTHR23119(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR052934|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:xHNrql5wX2JZV+9YxFGM7gm1/CY9606	rogid:5sqSFEOPSOBD89B6HPwdhZkqANc632	intact-crc:AA7116F0F4F557E1|rigid:49gCPPM9cnxBzJrSLFUcB3g7aD0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13571	uniprotkb:Q8CKI8	intact:EBI-2865663|uniprotkb:Q14698|uniprotkb:Q13240|uniprotkb:Q3KP54|ensembl:ENSP00000294507.3	intact:EBI-2855532	psi-mi:lapm5_human(display_long)|uniprotkb:LAPTM5(gene name)|psi-mi:LAPTM5(display_short)|uniprotkb:KIAA0085(gene name synonym)|uniprotkb:Lysosomal-associated multitransmembrane protein 5(gene name synonym)|uniprotkb:Retinoic acid-inducible E3 protein(gene name synonym)	psi-mi:q8cki8_yerpe(display_long)|uniprotkb:NCTC5923_02392(orf name)|uniprotkb:y3427(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865674|imex:IM-13779-7126	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006753.1|ensembl:ENSG00000162511.8(gene)|ensembl:ENST00000294507.4(transcript)|go:""GO:0002357""(defense response to tumor cell)|go:""GO:0002720""(positive regulation of cytokine production involved in immune response)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0012502""(induction of programmed cell death)|go:""GO:0030133""(transport vesicle)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050868""(negative regulation of T cell activation)|go:""GO:0050869""(negative regulation of B cell activation)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|go:""GO:0097214""(positive regulation of lysosomal membrane permeability)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903265""(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:1904093""(negative regulation of autophagic cell death)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000646""(positive regulation of receptor catabolic process)|interpro:IPR004687(Golgi 4-transmembrane spanning transporter)|interpro:IPR018396|interpro:IPR051115|mint:Q13571|panther:PTHR12479(orthology-group)"	refseq:WP_002213742.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oNH512GKUe4Y4qwd20918LMQzPE9606	rogid:kFpagl9Qd6b6ImFRX9++a7dnIjA632	intact-crc:3C5EA4233DA1075D|rigid:hyhFAlKz36wRdQREBwzsc8fNGUE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16719	uniprotkb:Q7CG77	intact:EBI-2865755|uniprotkb:Q6I9T2|uniprotkb:B2RCZ5|uniprotkb:D3DP79|uniprotkb:Q9BVW3|ensembl:ENSP00000264170.4|ensembl:ENSP00000386731.1	intact:EBI-2860845|uniprotkb:Q74Q13	psi-mi:kynu_human(display_long)|uniprotkb:KYNU(gene name)|psi-mi:KYNU(display_short)|uniprotkb:L-kynurenine hydrolase(gene name synonym)	psi-mi:nhaa_yerpe(display_long)|uniprotkb:nhaA(gene name)|psi-mi:nhaA(display_short)|uniprotkb:Sodium/proton antiporter NhaA(gene name synonym)|uniprotkb:YPO0470(locus name)|uniprotkb:YP_3710(locus name)|uniprotkb:y3704(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865752|imex:IM-13779-7133	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115919.15(gene)|ensembl:ENST00000264170.9(transcript)|ensembl:ENST00000409512.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006569""(L-tryptophan catabolic process)|go:""GO:0009435""(NAD biosynthetic process)|go:""GO:0019441""(L-tryptophan catabolic process to kynurenine)|go:""GO:0019805""(quinolinate biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0030429""(kynureninase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0034354""('de novo' NAD biosynthetic process from L-tryptophan)|go:""GO:0034516""(response to vitamin B6)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043420""(anthranilate metabolic process)|go:""GO:0097053""(L-kynurenine catabolic process)|interpro:IPR010111(Kynureninase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:2HZP|rcsb pdb:3E9K|rcsb pdb:7S3V|reactome:R-HSA-71240|refseq:NP_001028170.1|refseq:NP_001186170.1|refseq:NP_003928.1|refseq:XP_016860706.1|efo:""Orphanet:521438""|efo:""Orphanet:79155""|panther:PTHR14084(orthology-group)"	"interpro:IPR023171|interpro:IPR004670(Na+/H+ antiporter NhaA)|refseq:WP_002220711.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006885""(regulation of pH)|go:""GO:0015385""(""sodium:proton antiporter activity"")|refseq:YP_002345542.1|panther:PTHR30341(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fMHTxgRu54Dk8lnsj8iryqz3Kak9606	rogid:2jzd3JIvL38CrOPFxGfkKb82j14632	intact-crc:87B2E29202A7AC37|rigid:2rgAnxhEpY/qErFGeK4j/VrXS3g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q65AE7	uniprotkb:P11279	intact:EBI-2847916|uniprotkb:A0A3N4BMH0|uniprotkb:Q9ZGZ5|uniprotkb:A0A384LBG0|uniprotkb:A0A1U8QRS1|uniprotkb:Q7ARB3	intact:EBI-2805407|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40|ensembl:ENSP00000333298.4|uniprotkb:B4DWL3	psi-mi:q65ae7_yerpe(display_long)|uniprotkb:YPMT1.73(locus name)	psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865719|imex:IM-13779-7135	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025202|refseq:WP_002211757.1|refseq:NP_395419.1|refseq:YP_094002.1|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|interpro:IPR051406"	"refseq:NP_005552.3|ensembl:ENSG00000185896.11(gene)|ensembl:ENST00000332556.5(transcript)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0001618""(virus receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0044754""(autolysosome)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0061474""(phagolysosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072594""(establishment of protein localization to organelle)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0140507""(granzyme-mediated programmed cell death signaling pathway)|go:""GO:1902513""(regulation of organelle transport along microtubule)|interpro:IPR002000(""Lysosome-associated membrane glycoprotein (Lamp)/CD68"")|interpro:IPR018134|interpro:IPR048524|interpro:IPR048528|mint:P11279|rcsb pdb:8ATH|rcsb pdb:8FY5|rcsb pdb:8FYF|reactome:R-HSA-6798695|dip:DIP-44670N|panther:PTHR11506(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:BaOKn4oWF9wcKgOoNSaPk58oQ6k632	rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606	intact-crc:9EDE3058858E1708|rigid:GZuaF3EfFETCOOFCxFDw5Vz2kqo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8Z9U7	uniprotkb:O15230	intact:EBI-2844315|uniprotkb:Q0W9T9	intact:EBI-725060|uniprotkb:Q8WZA7|uniprotkb:Q9H1P1|uniprotkb:Q8TDF8|uniprotkb:Q5U4N9|ensembl:ENSP00000252999.3	psi-mi:dnaa_yerpe(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:YPO4097(locus name)|uniprotkb:y4113(locus name)|uniprotkb:YP_4005(locus name)	psi-mi:lama5_human(display_long)|uniprotkb:LAMA5(gene name)|psi-mi:LAMA5(display_short)|uniprotkb:KIAA0533(gene name synonym)|uniprotkb:KIAA1907(gene name synonym)|uniprotkb:Laminin-10 subunit alpha(gene name synonym)|uniprotkb:Laminin-11 subunit alpha(gene name synonym)|uniprotkb:Laminin-15 subunit alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865726|imex:IM-13779-7131	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR020591|interpro:IPR018312|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR024633|interpro:IPR027417|go:""GO:0003688""(DNA replication origin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006260""(DNA replication)|go:""GO:0006270""(DNA replication initiation)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002220732.1|interpro:IPR038454|refseq:YP_002348949.1|panther:PTHR30050(orthology-group)"	"efo:""Orphanet:521450""|ensembl:ENSG00000130702.15(gene)|ensembl:ENST00000252999.7(transcript)|go:""GO:0001658""(branching involved in ureteric bud morphogenesis)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0001942""(hair follicle development)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005610""(laminin-5 complex)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0007155""(cell adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007517""(muscle organ development)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0016477""(cell migration)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030324""(lung development)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0036484""(trunk neural crest cell migration)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0043083""(synaptic cleft)|go:""GO:0043259""(laminin-10 complex)|go:""GO:0043260""(laminin-11 complex)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0050678""(regulation of epithelial cell proliferation)|go:""GO:0060271""(cilium assembly)|go:""GO:0060445""(branching involved in salivary gland morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098631""(cell adhesion mediator activity)|go:""GO:0098965""(extracellular matrix of synaptic cleft)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099173""(postsynapse organization)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR050440|mint:O15230|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-6785807|reactome:R-HSA-8874081|refseq:NP_005551.3|panther:PTHR24035(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:quI/wKd39km6/ursW/cA4L2/N8E632	rogid:rSTl5zwwQKcbd20buKGffFtl3jI9606	intact-crc:1DCDC27872F44603|rigid:CzBtsYMB4VJV7Q2rm40K6E+XfN4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H1D8	uniprotkb:P18627	intact:EBI-2841465|uniprotkb:Q74SB2|uniprotkb:A0A384KZU6|uniprotkb:A0A0H2W6A2|uniprotkb:Q7CJK6|uniprotkb:A0A380PE06	intact:EBI-2830752|uniprotkb:A8K7T9|uniprotkb:Q7Z643|ensembl:ENSP00000203629.2	psi-mi:a0a2u2h1d8_yerpe(display_long)|uniprotkb:YPO2843(locus name)	psi-mi:lag3_human(display_long)|uniprotkb:LAG3(gene name)|psi-mi:LAG3(display_short)|uniprotkb:FDC(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865733|imex:IM-13779-7134	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0030313""(cell envelope)|refseq:WP_002209788.1|refseq:YP_002347781.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)"	"refseq:NP_002277.4|ensembl:ENSG00000089692.9(gene)|ensembl:ENST00000203629.3(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002270""(plasmacytoid dendritic cell activation)|go:""GO:0003823""(antigen binding)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0042110""(T cell activation)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045590""(negative regulation of regulatory T cell differentiation)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0050776""(regulation of immune response)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR036179|rcsb pdb:7TZG|rcsb pdb:7TZH|rcsb pdb:7UM3|rcsb pdb:8SO3|rcsb pdb:8SR0|reactome:R-HSA-2132295|panther:PTHR11890(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uWJg8z+dtILtJUaBb2TVOqdvobA632	rogid:LKgdGAeEExS57wqpGF8zyU2ODEw9606	intact-crc:C045B4AE274309F6|rigid:MtKA7ry+TqkSnsWqGM1bMHOI/9M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WV93	uniprotkb:Q8ZHI8	intact:EBI-2865743|uniprotkb:Q8N6A3|ensembl:ENSP00000357973.3	intact:EBI-2853665|uniprotkb:Q0WID5	psi-mi:afg1l_human(display_long)|uniprotkb:AFG1L(gene name)|psi-mi:AFG1L(display_short)|uniprotkb:AFG1(gene name synonym)|uniprotkb:LACE1(gene name synonym)|uniprotkb:Lactation elevated protein 1(gene name synonym)|uniprotkb:Protein AFG1 homolog(gene name synonym)	"psi-mi:gcsp_yerpe(display_long)|uniprotkb:gcvP(gene name)|psi-mi:gcvP(display_short)|uniprotkb:Glycine cleavage system P-protein(gene name synonym)|uniprotkb:Glycine decarboxylase(gene name synonym)|uniprotkb:""Glycine dehydrogenase (aminomethyl-transferring)""(gene name synonym)|uniprotkb:YPO0905(locus name)|uniprotkb:YP_3602(locus name)|uniprotkb:y3292(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865740|imex:IM-13779-7132	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_660358.2|refseq:NP_001309934.1|ensembl:ENSG00000135537.17(gene)|ensembl:ENST00000368977.9(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006123""(mitochondrial electron transport, cytochrome c to oxygen)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0035694""(mitochondrial protein catabolic process)|interpro:IPR005654(AFG1-like ATPase)|interpro:IPR027417|panther:PTHR12169(orthology-group)"	"refseq:WP_002209947.1|interpro:IPR020581|interpro:IPR003437(Glycine cleavage system P-protein)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:""GO:0004375""(""glycine dehydrogenase (decarboxylating) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0016594""(glycine binding)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR049315|interpro:IPR049316|refseq:YP_002345953.1|panther:PTHR11773(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zAGjAdA9mhQ9rAvSP/oJb845mfc9606	rogid:DyITTFcMLNG19IvzD1ZE6K5EW/U632	intact-crc:245294180D8CA6D2|rigid:Tg8rp1yRIopMUjGsmPuYkRw6Bn4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:P12956	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-353208|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|ensembl:ENSP00000352257.4|ensembl:ENSP00000353192.3|ensembl:ENSP00000384257.1|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8|intact:EBI-21355587	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865783|imex:IM-13779-7137	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:NP_001460.1|refseq:NP_001275905.1|ensembl:ENSG00000196419.13(gene)|ensembl:ENST00000359308.8(transcript)|ensembl:ENST00000360079.8(transcript)|ensembl:ENST00000405878.5(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000725""(recombinational repair)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000783""(nuclear telomere cap complex)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006266""(obsolete DNA ligation)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030332""(cyclin binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0043564""(""Ku70:Ku80 complex"")|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045621""(positive regulation of lymphocyte differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0051575""(5'-deoxyribose-5-phosphate lyase activity)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0071475""(cellular hyperosmotic salinity response)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097680""(double-strand break repair via classical nonhomologous end joining)|rcsb pdb:8ASC|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|interpro:IPR047087|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7Z6O|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:7ZT6|rcsb pdb:7ZVT|rcsb pdb:7ZWA|rcsb pdb:7ZYG|rcsb pdb:8AG4|rcsb pdb:8AG5|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|refseq:NP_001275906.1|dip:DIP-24188N|panther:PTHR12604(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/20	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	intact-crc:BC2FE4AD4D9C5F58|rigid:cvshZfvJ6z02gPgKJL/29+DSCNQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H129	uniprotkb:P12956	intact:EBI-2842176|uniprotkb:Q7ARE9|uniprotkb:A0A1U8QLB5|uniprotkb:O68740|uniprotkb:A0A384K8I4	intact:EBI-353208|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|ensembl:ENSP00000352257.4|ensembl:ENSP00000353192.3|ensembl:ENSP00000384257.1|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8|intact:EBI-21355587	psi-mi:a0a2u2h129_yerpe(display_long)|uniprotkb:YPMT1.23c(locus name)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865790|imex:IM-13779-7138	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395359.1	"refseq:NP_001460.1|refseq:NP_001275905.1|ensembl:ENSG00000196419.13(gene)|ensembl:ENST00000359308.8(transcript)|ensembl:ENST00000360079.8(transcript)|ensembl:ENST00000405878.5(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000725""(recombinational repair)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000783""(nuclear telomere cap complex)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006266""(obsolete DNA ligation)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030332""(cyclin binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0043564""(""Ku70:Ku80 complex"")|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045621""(positive regulation of lymphocyte differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0051575""(5'-deoxyribose-5-phosphate lyase activity)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0071475""(cellular hyperosmotic salinity response)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097680""(double-strand break repair via classical nonhomologous end joining)|rcsb pdb:8ASC|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|interpro:IPR047087|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7Z6O|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:7ZT6|rcsb pdb:7ZVT|rcsb pdb:7ZWA|rcsb pdb:7ZYG|rcsb pdb:8AG4|rcsb pdb:8AG5|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|refseq:NP_001275906.1|dip:DIP-24188N|panther:PTHR12604(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/20	rogid:4xa0lQiscvHi6CWXCiIT959GpQw632	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	intact-crc:9859F546F1437F0C|rigid:vHZjCWdDjvUa65t0awQuw9hEAdE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2865800	uniprotkb:P14618	-	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	psi-mi:a0a7d9nkm6_yerpe(display_short)|psi-mi:EBI-2865800(display_long)|uniprotkb:EGX46_23445(orf name)	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865797|imex:IM-13779-7140	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A7D9NKM6(uniprot-removed-ac)	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:7IE0h70zPFLxFUL9glVK0zxLtpg632	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	intact-crc:B4DB082043250823|rigid:kYZrwXuOesyV3MZ2wJZpDopObZA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P12956	uniprotkb:A0A0H2W4E2	intact:EBI-353208|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|ensembl:ENSP00000352257.4|ensembl:ENSP00000353192.3|ensembl:ENSP00000384257.1|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8|intact:EBI-21355587	intact:EBI-2865775|uniprotkb:Q74UC4|uniprotkb:Q7CIY2|uniprotkb:Q0WGA8	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:a0a0h2w4e2_yerpe(display_long)|uniprotkb:YPO1673(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865772|imex:IM-13779-7139	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001460.1|refseq:NP_001275905.1|ensembl:ENSG00000196419.13(gene)|ensembl:ENST00000359308.8(transcript)|ensembl:ENST00000360079.8(transcript)|ensembl:ENST00000405878.5(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000725""(recombinational repair)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000783""(nuclear telomere cap complex)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006266""(obsolete DNA ligation)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030332""(cyclin binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0043564""(""Ku70:Ku80 complex"")|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045621""(positive regulation of lymphocyte differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0051575""(5'-deoxyribose-5-phosphate lyase activity)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0071475""(cellular hyperosmotic salinity response)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097680""(double-strand break repair via classical nonhomologous end joining)|rcsb pdb:8ASC|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|interpro:IPR047087|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7Z6O|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:7ZT6|rcsb pdb:7ZVT|rcsb pdb:7ZWA|rcsb pdb:7ZYG|rcsb pdb:8AG4|rcsb pdb:8AG5|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|refseq:NP_001275906.1|dip:DIP-24188N|panther:PTHR12604(orthology-group)"	interpro:IPR019286|interpro:IPR014600(Uncharacterised conserved protein UCP035905, membrane protein)|refseq:WP_002210878.1|refseq:YP_002346680.1|panther:PTHR38434(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/20	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rogid:mKkVZyrmlvf5tcK2hl6LzwZVbzE632	intact-crc:B1C265FB982507AB|rigid:hVgCWhVTxzmSecINcuatkebr/OA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WJY2	uniprotkb:P12956	intact:EBI-2845073|uniprotkb:Q74XE9|uniprotkb:Q8D1F1	intact:EBI-353208|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|ensembl:ENSP00000352257.4|ensembl:ENSP00000353192.3|ensembl:ENSP00000384257.1|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8|intact:EBI-21355587	psi-mi:rham_yerpe(display_long)|uniprotkb:rhaM(gene name)|psi-mi:rhaM(display_short)|uniprotkb:Rhamnose 1-epimerase(gene name synonym)|uniprotkb:Type-3 mutarotase(gene name synonym)|uniprotkb:YPO0326(locus name)|uniprotkb:y0583(locus name)|uniprotkb:YP_0481(locus name)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865765|imex:IM-13779-7136	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR013448(L-rhamnose 1-epimerase)|interpro:IPR008000(Rhamnose mutarotase)|go:""GO:0005737""(cytoplasm)|go:""GO:0016857""(racemase and epimerase activity, acting on carbohydrates and derivatives)|go:""GO:0019301""(rhamnose catabolic process)|go:""GO:0062192""(L-rhamnose mutarotase activity)|refseq:WP_002209101.1|refseq:YP_002345406.1|panther:PTHR34389(orthology-group)"	"refseq:NP_001460.1|refseq:NP_001275905.1|ensembl:ENSG00000196419.13(gene)|ensembl:ENST00000359308.8(transcript)|ensembl:ENST00000360079.8(transcript)|ensembl:ENST00000405878.5(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000725""(recombinational repair)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000783""(nuclear telomere cap complex)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006266""(obsolete DNA ligation)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030332""(cyclin binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0043564""(""Ku70:Ku80 complex"")|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045621""(positive regulation of lymphocyte differentiation)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0051575""(5'-deoxyribose-5-phosphate lyase activity)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0071475""(cellular hyperosmotic salinity response)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097680""(double-strand break repair via classical nonhomologous end joining)|rcsb pdb:8ASC|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|interpro:IPR047087|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7Z6O|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:7ZT6|rcsb pdb:7ZVT|rcsb pdb:7ZWA|rcsb pdb:7ZYG|rcsb pdb:8AG4|rcsb pdb:8AG5|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|refseq:NP_001275906.1|dip:DIP-24188N|panther:PTHR12604(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/20	rogid:dKL6JZRhrixCXOBMlbiAQN79iik632	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	intact-crc:44A756891AC6A003|rigid:9KdDDEBJAIuySh+IgPBdu9pPxa0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14618	uniprotkb:Q8CZR5	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	intact:EBI-2839873	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	psi-mi:q8czr5_yerpe(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:y3537(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865822|imex:IM-13779-7144	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"interpro:IPR028630|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016987""(sigma factor activity)|interpro:IPR042189|interpro:IPR036388|interpro:IPR050239"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rogid:8NwL0C9CZc1yJ2fOOz9gZqJHCMI632	intact-crc:86DEADDB82388427|rigid:xmLlRKynW+L62pkXmF9SwufSOZY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14618	uniprotkb:A0A5P8YEG1	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	intact:EBI-2852022|uniprotkb:Q74UV9|uniprotkb:A0A2U2GXG2|uniprotkb:A0A0H2W3X6|uniprotkb:Q7CHY3|uniprotkb:A0A384KW77	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	psi-mi:a0a5p8yeg1_yerpe(display_long)|uniprotkb:flaS(gene name)|psi-mi:flaS(display_short)|uniprotkb:flaW(gene name synonym)|uniprotkb:flgK(gene name synonym)|uniprotkb:YPO1808(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865829|imex:IM-13779-7142	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR002371(Flagellar hook-associated protein)|refseq:WP_002211119.1|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009424""(bacterial-type flagellum hook)|go:""GO:0044780""(bacterial-type flagellum assembly)|interpro:IPR053927|interpro:IPR049119|refseq:YP_002346803.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rogid:pNXjB/cj8ecgLe9j2NLbgGL8sgw632	intact-crc:67B510451F287559|rigid:856SXXKm/nVcwEkiALZ1z/Kd/PU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WKG1	uniprotkb:P14618	intact:EBI-2855083|uniprotkb:Q74Y36|uniprotkb:A0A0H2W137|uniprotkb:A0A3N4AZM6|uniprotkb:Q7CFW7|uniprotkb:A0A384L9U0	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	psi-mi:q0wkg1_yerpe(display_long)|uniprotkb:YPO0141(locus name)	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865836|imex:IM-13779-7143	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|refseq:WP_002208909.1|go:""GO:0046872""(metal ion binding)|interpro:IPR050155|interpro:IPR036412|refseq:YP_002345227.1"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:C2n5rHIofpB8tAA4iKdS/lm5nZ4632	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	intact-crc:CDD9E8E40B4F9CA0|rigid:RjPNyDMY6duCyI/vVafB7r4+MTg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14618	uniprotkb:Q0WJY2	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	intact:EBI-2845073|uniprotkb:Q74XE9|uniprotkb:Q8D1F1	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	psi-mi:rham_yerpe(display_long)|uniprotkb:rhaM(gene name)|psi-mi:rhaM(display_short)|uniprotkb:Rhamnose 1-epimerase(gene name synonym)|uniprotkb:Type-3 mutarotase(gene name synonym)|uniprotkb:YPO0326(locus name)|uniprotkb:y0583(locus name)|uniprotkb:YP_0481(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865815|imex:IM-13779-7141	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR013448(L-rhamnose 1-epimerase)|interpro:IPR008000(Rhamnose mutarotase)|go:""GO:0005737""(cytoplasm)|go:""GO:0016857""(racemase and epimerase activity, acting on carbohydrates and derivatives)|go:""GO:0019301""(rhamnose catabolic process)|go:""GO:0062192""(L-rhamnose mutarotase activity)|refseq:WP_002209101.1|refseq:YP_002345406.1|panther:PTHR34389(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rogid:dKL6JZRhrixCXOBMlbiAQN79iik632	intact-crc:FDBA99E40BAC7F78|rigid:r5xt/jZRYLZpqX/WIhRAzedvidU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14618	uniprotkb:A0A3G5L6A1	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	intact:EBI-2862878	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	psi-mi:a0a3g5l6a1_yerpe(display_long)|uniprotkb:tcbA(gene name)|psi-mi:tcbA(display_short)|uniprotkb:YP_3865(locus name)|uniprotkb:y0184(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865808|imex:IM-13779-7145	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	uniprotkb:A0A2U2H2J5(uniprot-removed-ac)|interpro:IPR040840|interpro:IPR041079|interpro:IPR046839|refseq:WP_002220204.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rogid:kjRBO/f33i0tgY/JRYFkzLCun/4632	intact-crc:D714FBC5F8770475|rigid:1gnJ0D9UDVbKwIy6hYGVQUIGz7E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0B2	uniprotkb:Q96PQ7	intact:EBI-2850083|uniprotkb:Q74UX8	intact:EBI-2692595|uniprotkb:Q9Y2X2|uniprotkb:B7WP68|uniprotkb:Q86XW0|uniprotkb:A8K170|uniprotkb:Q9NVA9|uniprotkb:Q9NUK3|uniprotkb:Q9NV27|uniprotkb:F8WAE7|uniprotkb:Q6Y881|uniprotkb:E9PCF4|uniprotkb:G3XA92	psi-mi:q8d0b2_yerpe(display_long)|uniprotkb:fliH(gene name)|psi-mi:fliH(display_short)|uniprotkb:fliH1(gene name synonym)|uniprotkb:YP_1564(locus name)|uniprotkb:y2478(locus name)	psi-mi:klhl5_human(display_long)|uniprotkb:KLHL5(gene name)|psi-mi:KLHL5(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865877|imex:IM-13779-7150	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000563(Flagellar assembly protein FliH)|interpro:IPR018035|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0009288""(bacterial-type flagellum)|go:""GO:0015031""(protein transport)|go:""GO:0044781""(bacterial-type flagellum organization)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR051472"	"interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_057074.3|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR006652(Kelch repeat type 1)|refseq:NP_950240.2|mint:Q96PQ7|interpro:IPR030606|refseq:NP_001007076.1|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|reactome:R-HSA-8951664|reactome:R-HSA-983168|panther:PTHR24412(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pu9m0K/LYZp0hFWjqupRjpJzuhQ632	rogid:+A0OT194eLExAwwsaiUx1D8g6uQ9606	intact-crc:20AB8EA2C296ADBB|rigid:vfDG1gMvWN4XDqNX5aUOlX8NIEE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14618	uniprotkb:A0A2U2H1V8	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	intact:EBI-2842206|uniprotkb:O68762|uniprotkb:Q74YK8|uniprotkb:A0A384KZR0|uniprotkb:A0A1U8QG56|uniprotkb:A0A0H2W1K6|uniprotkb:Q7ARD1	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	psi-mi:a0a2u2h1v8_yerpe(display_long)|uniprotkb:YPMT1.47c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865843|imex:IM-13779-7146	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"refseq:NP_395390.1|refseq:YP_093935.1|refseq:WP_002222869.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rogid:HfbjH2+V5FcTdJjdFEwPlsVE9ek632	intact-crc:A1925247187F5540|rigid:xiIfk2Fp5qsBfr1wRyWOoc8QkUI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94806	uniprotkb:A0A5P8YAM6	intact:EBI-1255366|uniprotkb:Q53TR7|uniprotkb:Q8NEL8|uniprotkb:D6W587|ensembl:ENSP00000234179.2|ensembl:ENSP00000368356.1	intact:EBI-2844150|uniprotkb:Q7CFP2|uniprotkb:Q0W9V4	psi-mi:kpcd3_human(display_long)|uniprotkb:PRKD3(gene name)|psi-mi:PRKD3(display_short)|uniprotkb:EPK2(gene name synonym)|uniprotkb:PRKCN(gene name synonym)|uniprotkb:Protein kinase C nu type(gene name synonym)|uniprotkb:nPKC-nu(gene name synonym)|uniprotkb:Protein kinase EPK2(gene name synonym)	psi-mi:a0a5p8yam6_yerpe(display_long)|uniprotkb:malS(gene name)|psi-mi:malS(display_short)|uniprotkb:YPO4080(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865863|imex:IM-13779-7147	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005804.1|ensembl:ENSG00000115825.11(gene)|ensembl:ENST00000234179.8(transcript)|ensembl:ENST00000379066.5(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004697""(diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004698""(calcium,diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004699""(diacylglycerol-dependent, calcium-independent serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007200""(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:0016301""(kinase activity)|go:""GO:0030148""(sphingolipid biosynthetic process)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0046872""(metal ion binding)|go:""GO:0106310""(protein serine kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015727(Protein kinase C mu-related)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR046349|mint:O94806|rcsb pdb:2D9Z|reactome:R-HSA-1660661|refseq:XP_005264294.1|panther:PTHR22968(orthology-group)"	"interpro:IPR014635(Alpha-amylase, MalS type)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209631.1|go:""GO:0004556""(alpha-amylase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0009313""(oligosaccharide catabolic process)|go:""GO:0030980""(alpha-glucan catabolic process)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348934.1|panther:PTHR10357(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UgwsN9a5nJT53K2HrD1E94A5HWc9606	rogid:qjQekYtSF56tT51Uzp+xShmXohk632	intact-crc:8A7F77A785EBEF55|rigid:GycYdS4XKE9csg9CdbehfxLhe7Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CWG4	uniprotkb:P24723	intact:EBI-2856530|uniprotkb:Q74QZ9	intact:EBI-2865850|uniprotkb:Q8NE03|uniprotkb:Q16246|uniprotkb:B4DJN5	psi-mi:q8cwg4_yerpe(display_long)|uniprotkb:glpD(gene name)|psi-mi:glpD(display_short)|uniprotkb:YP_3299(locus name)|uniprotkb:y3891(locus name)	psi-mi:kpcl_human(display_long)|uniprotkb:PRKCH(gene name)|psi-mi:PRKCH(display_short)|uniprotkb:PKCL(gene name synonym)|uniprotkb:PRKCL(gene name synonym)|uniprotkb:PKC-L(gene name synonym)|uniprotkb:nPKC-eta(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865856|imex:IM-13779-7149	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR031656|go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0006072""(glycerol-3-phosphate metabolic process)|go:""GO:0009331""(""glycerol-3-phosphate dehydrogenase (FAD) complex"")|interpro:IPR038299|interpro:IPR036188"	"go:""GO:0004699""(diacylglycerol-dependent, calcium-independent serine/threonine kinase activity)|go:""GO:0070528""(protein kinase C signaling)|ensembl:ENST00000332981|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005524""(ATP binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0004697""(diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0030168""(platelet activation)|refseq:NP_006246.2|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR020454|interpro:IPR011009(Protein kinase-like)|interpro:IPR017892|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:2FK9|ensembl:ENSP00000450981|ensembl:ENST00000555082|go:""GO:0070062""(extracellular exosome)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0034351""(negative regulation of glial cell apoptotic process)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0050861""(positive regulation of B cell receptor signaling pathway)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|rcsb pdb:3TXO|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0007165""(signal transduction)|interpro:IPR027431|go:""GO:0005737""(cytoplasm)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0019899""(enzyme binding)|ensembl:ENSG00000027075|ensembl:ENSP00000329127|go:""GO:0005911""(cell-cell junction)|reactome:R-HSA-114508|reactome:R-HSA-418597|go:""GO:0017160""|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|interpro:IPR034665|refseq:XP_016876947.1|dip:DIP-44588N|mint:MINT-3973608|go:""GO:0004674""(protein serine/threonine kinase activity)|interpro:IPR035892|go:""GO:0004698""(calcium,diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0106311""|rcsb pdb:8FP3|rcsb pdb:8FP1|ensembl:ENST00000332981.11|ensembl:ENSP00000329127.5|ensembl:ENSG00000027075.17|ensembl:ENST00000555082.5|ensembl:ENSP00000450981.1|go:""GO:0004672""(protein kinase activity)|go:""GO:0031267""(small GTPase binding)|go:""GO:0030154""(cell differentiation)|interpro:IPR046349|panther:PTHR24356(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:R9I22ZXVmXiKYYz/+NgwNjlHCb0632	rogid:wqrydF3n2dujiiKKk44XmuQSuJk9606	intact-crc:75AFE32BC57C1AD3|rigid:TGHgMGCxhbYg91gOyiHvVGyAclQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P05771	uniprotkb:Q8D0H8	intact:EBI-706216|uniprotkb:O43744|uniprotkb:P05127|uniprotkb:Q15138|uniprotkb:Q93060|uniprotkb:Q9UE49|uniprotkb:Q9UE50|uniprotkb:Q9UEH8|uniprotkb:Q9UJ30|uniprotkb:Q9UJ33|uniprotkb:C5IFJ8|intact:EBI-3396567|uniprotkb:D3DWF5|ensembl:ENSP00000318315.7	intact:EBI-2851077|uniprotkb:Q74TS0	psi-mi:kpcb_human(display_long)|uniprotkb:PRKCB1(gene name synonym)|uniprotkb:PKCB(gene name synonym)|uniprotkb:PRKCB(gene name)|psi-mi:PRKCB(display_short)	psi-mi:q8d0h8_yerpe(display_long)|uniprotkb:y2119(locus name)|uniprotkb:amn(gene name)|psi-mi:amn(display_short)|uniprotkb:YP_2074(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865870|imex:IM-13779-7148	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002729.2|refseq:NP_997700.1|dip:DIP-34187N|ensembl:ENSG00000166501.14(gene)|ensembl:ENST00000321728.12(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003682""(chromatin binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004697""(diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004698""(calcium,diacylglycerol-dependent serine/threonine kinase activity)|go:""GO:0004699""(diacylglycerol-dependent, calcium-independent serine/threonine kinase activity)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005246""(calcium channel regulator activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006816""(calcium ion transport)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006915""(apoptotic process)|go:""GO:0007077""(mitotic nuclear membrane disassembly)|go:""GO:0007165""(signal transduction)|go:""GO:0007207""(phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway)|go:""GO:0008091""(spectrin)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009749""(response to glucose)|go:""GO:0010827""(regulation of D-glucose transmembrane transport)|go:""GO:0010829""(negative regulation of D-glucose transmembrane transport)|go:""GO:0014059""(regulation of dopamine secretion)|go:""GO:0018894""(dibenzo-p-dioxin metabolic process)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031526""(brush border membrane)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0033280""(response to vitamin D)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0040008""(regulation of growth)|go:""GO:0042113""(B cell activation)|go:""GO:0042393""(histone binding)|go:""GO:0042488""(positive regulation of odontogenesis of dentin-containing tooth)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0044305""(calyx of Held)|go:""GO:0045471""(response to ethanol)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071322""(cellular response to carbohydrate stimulus)|go:""GO:0099171""(presynaptic modulation of chemical synaptic transmission)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034664|interpro:IPR035892|interpro:IPR046349|mint:P05771|rcsb pdb:2I0E|rcsb pdb:8SG2|reactome:R-HSA-114516|reactome:R-HSA-1169091|reactome:R-HSA-416993|reactome:R-HSA-418597|reactome:R-HSA-4419969|reactome:R-HSA-5099900|reactome:R-HSA-5218921|reactome:R-HSA-5668599|reactome:R-HSA-76005|reactome:R-HSA-8939246|panther:PTHR24356(orthology-group)"	"interpro:IPR011271(AMP nucleosidase)|interpro:IPR018953|interpro:IPR000845(Nucleoside phosphorylase)|go:""GO:0008714""(AMP nucleosidase activity)|go:""GO:0009116""(nucleoside metabolic process)|go:""GO:0044209""(AMP salvage)|interpro:IPR035994|interpro:IPR037109|interpro:IPR047039"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:racpanFwAtAbFzE9i3iiHQBPCyg9606	rogid:pQne2oycJKd7ymLLAwCsL1/6V8U632	intact-crc:52B2D361A8D041E1|rigid:MnSqq/vpn9rEq8utKArLUqqeoYA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99612	uniprotkb:A0A3G5KZU3	intact:EBI-714994|uniprotkb:Q5VUT7|uniprotkb:Q5VUT8|uniprotkb:Q9BT79|uniprotkb:B4DDN0|uniprotkb:B2RE86|uniprotkb:D3DRR1|uniprotkb:F5H3M5|ensembl:ENSP00000419923.1	intact:EBI-2850940	psi-mi:klf6_human(display_long)|uniprotkb:Core promoter element-binding protein(gene name synonym)|uniprotkb:B-cell-derived protein 1(gene name synonym)|uniprotkb:Proto-oncogene BCD1(gene name synonym)|uniprotkb:Transcription factor Zf9(gene name synonym)|uniprotkb:GC-rich sites-binding factor GBF(gene name synonym)|uniprotkb:KLF6(gene name)|psi-mi:KLF6(display_short)|uniprotkb:BCD1(gene name synonym)|uniprotkb:COPEB(gene name synonym)|uniprotkb:CPBP(gene name synonym)|uniprotkb:ST12(gene name synonym)|uniprotkb:Suppressor of tumorigenicity 12 protein(gene name synonym)	psi-mi:a0a3g5kzu3_yerpe(display_long)|uniprotkb:y0245(locus name)|uniprotkb:ssuA(gene name)|psi-mi:ssuA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865917|imex:IM-13779-7153	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001153596.1|refseq:NP_001153597.1|refseq:NP_001291.3|ensembl:ENSG00000067082.15(gene)|ensembl:ENST00000497571.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001650""(fibrillar center)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0030183""(B cell differentiation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|panther:PTHR23235(orthology-group)"	"interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR010067(ABC transporter, substrate-binding protein, aliphatic sulphonates)|interpro:IPR015168(NMT1/THI5 like)|uniprotkb:A0A6B3T643(uniprot-removed-ac)|go:""GO:0016020""(membrane)|go:""GO:0042597""(periplasmic space)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|refseq:WP_002220949.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7CEBj1T+XZQv6TwLVHkXreZOkXQ9606	rogid:kuMqjHfkYUIBJ4hy+1j+bwqjjo4632	intact-crc:B66723F67C73871F|rigid:kMjHD9z+uliDjrFWwqm0k3Y9m5E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2M5	uniprotkb:Q8CZU2	intact:EBI-714379|uniprotkb:Q5TZF2|uniprotkb:Q9H457|uniprotkb:B3KMA0|uniprotkb:Q5ZF45|ensembl:ENSP00000209884.4|uniprotkb:B4DUR0	intact:EBI-2843382	psi-mi:klh20_human(display_long)|uniprotkb:KLHL20(gene name)|psi-mi:KLHL20(display_short)|uniprotkb:KLEIP(gene name synonym)|uniprotkb:Kelch-like ECT2-interacting protein(gene name synonym)|uniprotkb:Kelch-like protein X(gene name synonym)|uniprotkb:KLHLX(gene name synonym)	psi-mi:q8czu2_yerpe(display_long)|uniprotkb:yapH(gene name)|psi-mi:yapH(display_short)|uniprotkb:y3396(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865891|imex:IM-13779-7151	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055273.2|refseq:XP_005245150.1|ensembl:ENSG00000076321.11(gene)|ensembl:ENST00000209884.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016605""(PML body)|go:""GO:0019964""(type II interferon binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:1990390""(protein K33-linked ubiquitination)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q9Y2M5|rcsb pdb:5YQ4|rcsb pdb:6GY5|rcsb pdb:8CIA|reactome:R-HSA-8951664|reactome:R-HSA-983168|panther:PTHR24412(orthology-group)"	"interpro:IPR024973|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|go:""GO:0019867""(outer membrane)|interpro:IPR036709|interpro:IPR043990|interpro:IPR050909"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3MyNIHmvjvjumxy4csUdrbMg5wI9606	rogid:w2l6qUtIv4INNGQ9HeM84bFptXU632	intact-crc:3233FE6FB9BE43E4|rigid:qXUO+cWtRDelAi+Ym1rKgPZ1h5s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2M5	uniprotkb:Q7ARD3	intact:EBI-714379|uniprotkb:Q5TZF2|uniprotkb:Q9H457|uniprotkb:B3KMA0|uniprotkb:Q5ZF45|ensembl:ENSP00000209884.4|uniprotkb:B4DUR0	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:klh20_human(display_long)|uniprotkb:KLHL20(gene name)|psi-mi:KLHL20(display_short)|uniprotkb:KLEIP(gene name synonym)|uniprotkb:Kelch-like ECT2-interacting protein(gene name synonym)|uniprotkb:Kelch-like protein X(gene name synonym)|uniprotkb:KLHLX(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865898|imex:IM-13779-7154	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055273.2|refseq:XP_005245150.1|ensembl:ENSG00000076321.11(gene)|ensembl:ENST00000209884.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016605""(PML body)|go:""GO:0019964""(type II interferon binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:1990390""(protein K33-linked ubiquitination)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q9Y2M5|rcsb pdb:5YQ4|rcsb pdb:6GY5|rcsb pdb:8CIA|reactome:R-HSA-8951664|reactome:R-HSA-983168|panther:PTHR24412(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3MyNIHmvjvjumxy4csUdrbMg5wI9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:9488787466E72D72|rigid:uEg16mFBYBM4Ud+NJ0oDH469MRU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0W1	uniprotkb:O95198	intact:EBI-2841250|uniprotkb:Q74SK3	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725.6	psi-mi:q8d0w1_yerpe(display_long)|uniprotkb:csgG(gene name)|psi-mi:csgG(display_short)|uniprotkb:YP_2597(locus name)|uniprotkb:y1512(locus name)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865884|imex:IM-13779-7155	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005534(Curli production assembly/transport component CsgG)|go:""GO:0005886""(plasma membrane)|go:""GO:0030288""(outer membrane-bounded periplasmic space)"	"refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|go:""GO:0030027""(lamellipodium)|ensembl:ENSG00000109466.14(gene)|ensembl:ENST00000226725.11(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0003779""(actin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|panther:PTHR24412(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zwYB9F8vJ7Vkr8em8p8HTA+eROA632	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:382EEDE06FF3C090|rigid:BTRK6P0Ksh0rjCZUKZAv8BYXfpE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q53G59	uniprotkb:Q8ZDJ6	intact:EBI-740929|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5|ensembl:ENSP00000356230.3	intact:EBI-2865905|uniprotkb:Q0WDW1	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:acka_yerpe(display_long)|uniprotkb:ackA(gene name)|psi-mi:ackA(display_short)|uniprotkb:Acetokinase(gene name synonym)|uniprotkb:YPO2566(locus name)|uniprotkb:y1622(locus name)|uniprotkb:YP_2377(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865910|imex:IM-13779-7152	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_067646.1|refseq:NP_001289980.1|refseq:NP_001290038.1|ensembl:ENSG00000117153.16(gene)|ensembl:ENST00000367261.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0014029""(neural crest formation)|go:""GO:0014032""(neural crest cell development)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030127""(COPII vesicle coat)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|rcsb pdb:8OIO|reactome:R-HSA-4641258|panther:PTHR24412(orthology-group)"	"interpro:IPR004372(Acetate kinase)|interpro:IPR000890(Acetate and butyrate kinase)|interpro:IPR023865|refseq:WP_002210288.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006083""(acetate metabolic process)|go:""GO:0006085""(acetyl-CoA biosynthetic process)|go:""GO:0008776""(acetate kinase activity)|interpro:IPR043129|refseq:YP_002347527.1|panther:PTHR21060(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	rogid:laqPr/u4TJOWNxdBPCNUDCcoDBw632	intact-crc:F85B315D80D7C31B|rigid:HUhyGeCqoTKPr2ykJgTfMXeUHKU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92845	uniprotkb:A0A0H2W6E9	intact:EBI-954040|uniprotkb:Q9H416|uniprotkb:Q8NHU7|uniprotkb:B2RDL1|uniprotkb:B1AKU4|uniprotkb:B7Z8A3|uniprotkb:F5H591|uniprotkb:B1AKU5|ensembl:ENSP00000354560.2	intact:EBI-2853427|uniprotkb:Q74WL2|uniprotkb:Q74XZ4|uniprotkb:Q74WU0|uniprotkb:Q8CLY1	psi-mi:kifa3_human(display_long)|uniprotkb:Smg GDS-associated protein(gene name synonym)|uniprotkb:KIFAP3(gene name)|psi-mi:KIFAP3(display_short)|uniprotkb:SMAP(gene name synonym)|uniprotkb:KIF3AP(gene name synonym)	psi-mi:a0a0h2w6e9_yerpe(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865945|imex:IM-13779-7158	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191443.1|refseq:NP_001191445.1|refseq:NP_001191446.1|refseq:NP_055785.2|ensembl:ENSG00000075945.13(gene)|ensembl:ENST00000361580.7(transcript)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0005930""(axoneme)|go:""GO:0007017""(microtubule-based process)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007165""(signal transduction)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007406""(negative regulation of neuroblast proliferation)|go:""GO:0008104""(protein localization)|go:""GO:0010659""(cardiac muscle cell apoptotic process)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016939""(kinesin II complex)|go:""GO:0019894""(kinesin binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0035869""(ciliary transition zone)|go:""GO:0036064""(ciliary basal body)|go:""GO:0044782""(cilium organization)|go:""GO:0046587""(positive regulation of calcium-dependent cell-cell adhesion)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070242""(thymocyte apoptotic process)|go:""GO:0070244""(negative regulation of thymocyte apoptotic process)|go:""GO:0072383""(plus-end-directed vesicle transport along microtubule)|go:""GO:0097542""(ciliary tip)|go:""GO:0098794""(postsynapse)|go:""GO:0098971""(anterograde dendritic transport of neurotransmitter receptor complex)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0120170""(intraciliary transport particle B binding)|go:""GO:1990075""(periciliary membrane compartment)|interpro:IPR000225(Armadillo)|interpro:IPR008658(Kinesin-associated)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q92845|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|panther:PTHR15605(orthology-group)"	"refseq:YP_093918.1|interpro:IPR002686(Transposase IS200-like)|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)|interpro:IPR036515"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pEcMuA/HlGJKpLQzlt1/R00TZ3Q9606	rogid:7GOftNTJxtzq5aUbatG8ug5sIa0632	intact-crc:F7504857D135C2BA|rigid:/RONR0iw8GpwPCx+42/hVjqKbNk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PHG3	uniprotkb:Q9H0B6	intact:EBI-2842233|uniprotkb:Q74PG3|uniprotkb:Q7CL31|uniprotkb:A0A3N4AZ01|uniprotkb:Q0WB47	intact:EBI-726994|uniprotkb:Q9H9C8|uniprotkb:Q9HA20|uniprotkb:B2RDY4|uniprotkb:A8MXL7|ensembl:ENSP00000314837.5|ensembl:ENSP00000377631.2|ensembl:ENSP00000399403.1	psi-mi:a0a380phg3_yerpe(display_long)|uniprotkb:YPO3606(locus name)	psi-mi:klc2_human(display_long)|uniprotkb:KLC2(gene name)|psi-mi:KLC2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865938|imex:IM-13779-7157	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)|refseq:YP_002348491.1|interpro:IPR050708	"ensembl:ENSG00000174996.12(gene)|ensembl:ENST00000316924.9(transcript)|ensembl:ENST00000394067.7(transcript)|ensembl:ENST00000417856.5(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0016020""(membrane)|go:""GO:0016938""(kinesin I complex)|go:""GO:0019894""(kinesin binding)|go:""GO:0032418""(lysosome localization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0045296""(cadherin binding)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q9H0B6|rcsb pdb:3CEQ|rcsb pdb:3EDT|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_001128246.1|refseq:NP_001128247.1|refseq:NP_001128248.1|refseq:NP_001305663.1|refseq:NP_073733.1|refseq:XP_005274240.1|efo:""Orphanet:320406""|dip:DIP-40381N|panther:PTHR45783(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:PzVVL6ecmr6Zs6wykTzdxHOJ3TQ632	rogid:VjzT5tI182sjUbhjxC1bK9GSMHo9606	intact-crc:1CA54BDDC51753E9|rigid:FHws0RCWpNoohgO6Vl0BXJelhgI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13118	uniprotkb:A0A380PDY1	intact:EBI-1389509|uniprotkb:Q503B2|uniprotkb:B2R794|intact:EBI-3962407|uniprotkb:A8MVH0|uniprotkb:O75411|uniprotkb:L0R4P6|uniprotkb:L0R679|ensembl:ENSP00000285407.6	intact:EBI-2848416|uniprotkb:Q74UI0|uniprotkb:A0A0H2W558|uniprotkb:Q7CIW0|uniprotkb:A0A384L8E0	psi-mi:klf10_human(display_long)|uniprotkb:Transforming growth factor-beta-inducible early growth response protein 1(gene name synonym)|uniprotkb:EGR-alpha(gene name synonym)|uniprotkb:KLF10(gene name)|psi-mi:KLF10(display_short)|uniprotkb:TIEG(gene name synonym)|uniprotkb:TIEG1(gene name synonym)	psi-mi:a0a380pdy1_yerpe(display_long)|uniprotkb:ogl(gene name)|psi-mi:ogl(display_short)|uniprotkb:YPO1713(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865931|imex:IM-13779-7159	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001027453.1|refseq:NP_005646.1|ensembl:ENSG00000155090.15(gene)|ensembl:ENST00000285407.11(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0030282""(bone mineralization)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0045672""(positive regulation of osteoclast differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q13118|rcsb pdb:2EPA|panther:PTHR23235(orthology-group)"	"interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027946|refseq:WP_002210841.1|go:""GO:0045490""(pectin catabolic process)|go:""GO:0047487""(oligogalacturonide lyase activity)|refseq:YP_002346716.1|panther:PTHR36842(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zn9npr6/dmo7T/4AiUnHQPHR4409606	rogid:e8mn+xTHxqbWMCnpEvzfGUD7MYI632	intact-crc:0059C7DDFF15BDC5|rigid:LetyQmyJR3ovJ8vIycGXlad3/vA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0V8	uniprotkb:Q99612	intact:EBI-2843099	intact:EBI-714994|uniprotkb:Q5VUT7|uniprotkb:Q5VUT8|uniprotkb:Q9BT79|uniprotkb:B4DDN0|uniprotkb:B2RE86|uniprotkb:D3DRR1|uniprotkb:F5H3M5|ensembl:ENSP00000419923.1	psi-mi:q8d0v8_yerpe(display_long)|uniprotkb:y1519(locus name)	psi-mi:klf6_human(display_long)|uniprotkb:Core promoter element-binding protein(gene name synonym)|uniprotkb:B-cell-derived protein 1(gene name synonym)|uniprotkb:Proto-oncogene BCD1(gene name synonym)|uniprotkb:Transcription factor Zf9(gene name synonym)|uniprotkb:GC-rich sites-binding factor GBF(gene name synonym)|uniprotkb:KLF6(gene name)|psi-mi:KLF6(display_short)|uniprotkb:BCD1(gene name synonym)|uniprotkb:COPEB(gene name synonym)|uniprotkb:CPBP(gene name synonym)|uniprotkb:ST12(gene name synonym)|uniprotkb:Suppressor of tumorigenicity 12 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865924|imex:IM-13779-7156	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011888(Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR019546|interpro:IPR027467|go:""GO:0009389""(dimethyl sulfoxide reductase activity)|go:""GO:0030151""(molybdenum ion binding)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR050612"	"refseq:NP_001153596.1|refseq:NP_001153597.1|refseq:NP_001291.3|ensembl:ENSG00000067082.15(gene)|ensembl:ENST00000497571.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001650""(fibrillar center)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0030183""(B cell differentiation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|panther:PTHR23235(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CcHr0E9LratmjBgXeGfmzvxLVPo632	rogid:7CEBj1T+XZQv6TwLVHkXreZOkXQ9606	intact-crc:760E0DB1EC583A32|rigid:h3NqjZSgba8AOX/htM942McTeRM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYT1	uniprotkb:O43896	intact:EBI-2850019|uniprotkb:Q74UX9|uniprotkb:A0A5P8YEY5|uniprotkb:A0A0H2W327|uniprotkb:Q7CHZ4|uniprotkb:A0A384L0J7	intact:EBI-1644048|uniprotkb:O75186|uniprotkb:Q5U618|uniprotkb:D3DTL6|ensembl:ENSP00000320821.5	psi-mi:a0a2u2gyt1_yerpe(display_long)|uniprotkb:fla AII.2(gene name)|psi-mi:fla AII.2(display_short)|uniprotkb:fla BII(gene name synonym)|uniprotkb:fliG(gene name synonym)|uniprotkb:YPO1829(locus name)	psi-mi:kif1c_human(display_long)|uniprotkb:KIF1C(gene name)|psi-mi:KIF1C(display_short)|uniprotkb:KIAA0706(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865952|imex:IM-13779-7160	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023087|interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR028263|refseq:WP_002211142.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:YP_002346825.1"	"dip:DIP-40376N|ensembl:ENSG00000129250.12(gene)|ensembl:ENST00000320785.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0008017""(microtubule binding)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990048""(anterograde neuronal dense core vesicle transport)|go:""GO:1990049""(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR027417|interpro:IPR032405|interpro:IPR036961|mint:O43896|rcsb pdb:2G1L|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_006603.2|refseq:XP_005256481.1|efo:""Orphanet:397946""|panther:PTHR24115(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:YBRmcuS18DJP2sfWEnw15dGyeYk632	rogid:AeG87fdDj70xFfsQCPuXA9iiubo9606	intact-crc:CFF14327F6AE71F8|rigid:YzUT2GLttrTi0JBVcd8YS6Nx3jY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60333	uniprotkb:Q8CLF6	intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4|ensembl:ENSP00000366290.1|ensembl:ENSP00000502065.1	intact:EBI-2850623	psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym)	psi-mi:q8clf6_yerpe(display_long)|uniprotkb:y1477(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865959|imex:IM-13779-7165	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:29072""|efo:""Orphanet:99946""|ensembl:ENSG00000054523.20(gene)|ensembl:ENST00000377086.5(transcript)|ensembl:ENST00000676179.1(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0006915""(apoptotic process)|go:""GO:0007270""(neuron-neuron synaptic transmission)|go:""GO:0007274""(neuromuscular synaptic transmission)|go:""GO:0008017""(microtubule binding)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019894""(kinesin binding)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0043005""(neuron projection)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048490""(anterograde synaptic vesicle transport)|go:""GO:1902742""(apoptotic process involved in development)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990049""(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR032405|interpro:IPR036961|interpro:IPR049780|mint:O60333|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N|panther:PTHR24115(orthology-group)"	"interpro:IPR000994(Peptidase M24, catalytic core)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|interpro:IPR029149|interpro:IPR036005|interpro:IPR050659"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/28	rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606	rogid:9ryjaFmbaczIybL5d+xLkpkN6DU632	intact-crc:1DC71BB5B7C97501|rigid:9YbDR9jR4Z4MDiNoFYoeFmElHi0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46013	uniprotkb:A0A2U2GYS8	intact:EBI-876367|uniprotkb:Q5VWH2|ensembl:ENSP00000357643.3	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	psi-mi:ki67_human(display_long)|uniprotkb:MKI67(gene name)|psi-mi:MKI67(display_short)|uniprotkb:Antigen identified by monoclonal antibody Ki-67(gene name synonym)	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865966|imex:IM-13779-7161	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001139438.1|refseq:NP_002408.3|panther:PTHR21603(orthology-group)|ensembl:ENSG00000148773.14(gene)|ensembl:ENST00000368654.8(transcript)|go:""GO:0000793""(condensed chromosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007088""(regulation of mitotic nuclear division)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0051983""(regulation of chromosome segregation)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1902275""(regulation of chromatin organization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012568(K167R)|interpro:IPR029334|mint:P46013|rcsb pdb:1R21|rcsb pdb:2AFF|rcsb pdb:5J28|dip:DIP-28132N"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:kyrLLOv4HSqah1Y6HtzebG978Kw9606	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	intact-crc:C36CF4E6B73E0FE4|rigid:LvXSoO/hAFnCc1S7T5uQGu4VFi8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14954	uniprotkb:P40127	intact:EBI-2865976|uniprotkb:O43471|uniprotkb:K7QUS8|ensembl:ENSP00000478711.1|ensembl:ENSP00000481628.1|ensembl:ENSP00000482060.1|ensembl:ENSP00000482170.1|ensembl:ENSP00000482900.1|ensembl:ENSP00000483434.1|ensembl:ENSP00000491232.1|ensembl:ENSP00000492239.1|ensembl:ENSP00000492347.1|ensembl:ENSP00000494266.1|ensembl:ENSP00000494623.1|ensembl:ENSP00000495438.1	intact:EBI-2844091|uniprotkb:Q0WAG2	psi-mi:ki2s1_human(display_long)|uniprotkb:KIR2DS1(gene name)|psi-mi:KIR2DS1(display_short)|uniprotkb:CD158H(gene name synonym)|uniprotkb:CD158 antigen-like family member H(gene name synonym)|uniprotkb:MHC class I NK cell receptor Eb6 ActI(gene name synonym)	psi-mi:cyaa_yerpe(display_long)|uniprotkb:cya(gene name)|psi-mi:cya(display_short)|uniprotkb:cyaA(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:YPO3848(locus name)|uniprotkb:y0382(locus name)|uniprotkb:YP_3199(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865973|imex:IM-13779-7164	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055327.1|ensembl:ENSG00000273517.1(gene)|ensembl:ENSG00000273603.1(gene)|ensembl:ENSG00000275421.1(gene)|ensembl:ENSG00000276327.1(gene)|ensembl:ENSG00000278120.1(gene)|ensembl:ENSG00000278304.1(gene)|ensembl:ENSG00000284120.3(gene)|ensembl:ENSG00000284150.3(gene)|ensembl:ENSG00000284560.3(gene)|ensembl:ENST00000611996.1(transcript)|ensembl:ENST00000612447.1(transcript)|ensembl:ENST00000617661.1(transcript)|ensembl:ENST00000618071.1(transcript)|ensembl:ENST00000621207.1(transcript)|ensembl:ENST00000622039.1(transcript)|ensembl:ENST00000638832.1(transcript)|ensembl:ENST00000639093.1(transcript)|ensembl:ENST00000639232.1(transcript)|ensembl:ENST00000643062.1(transcript)|ensembl:ENST00000644318.1(transcript)|ensembl:ENST00000645834.1(transcript)|go:""GO:0002764""(immune response-regulating signaling pathway)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016020""(membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050412|reactome:R-HSA-198933|reactome:R-HSA-2172127|panther:PTHR11738(orthology-group)"	"interpro:IPR000274(Adenylate cyclase, class-I)|interpro:IPR024686|interpro:IPR024685|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006171""(cAMP biosynthetic process)|refseq:WP_002211468.1|refseq:YP_002348726.1|panther:PTHR38760(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:crOV0FYXEakUxq57/gP4Rbei6+g9606	rogid:l0RzY0/qkJ4UmTdMusK/+DQB0ow632	intact-crc:245061916A9DE905|rigid:Eu6KZu0NpyDVXqLrNHppwvnHCb0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5L4I2	uniprotkb:Q7Z4H8	intact:EBI-2843457	intact:EBI-2865988|uniprotkb:Q8NE24|uniprotkb:Q8N7L8|uniprotkb:Q6UWW2|uniprotkb:Q6ZUM9|ensembl:ENSP00000315386.5	psi-mi:a0a3g5l4i2_yerpe(display_long)|uniprotkb:tap(gene name)|psi-mi:tap(display_short)|uniprotkb:YP_1807(locus name)|uniprotkb:y1838(locus name)	psi-mi:plgt3_human(display_long)|uniprotkb:POGLUT3(gene name)|psi-mi:POGLUT3(display_short)|uniprotkb:KDEL motif-containing protein 2(gene name synonym)|uniprotkb:KDELC2(gene name synonym)|uniprotkb:Protein O-xylosyltransferase POGLUT3(gene name synonym)|uniprotkb:UNQ1904/PRO4350(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2865985|imex:IM-13779-7162	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|uniprotkb:A0A5P8YGR7(uniprot-removed-ac)|interpro:IPR003122(Chemotaxis methyl-accepting receptor, ligand-binding)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004091(Chemotaxis methyl-accepting receptor, methyl-accepting site)|interpro:IPR035440|refseq:WP_002220817.1|interpro:IPR051310"	"refseq:NP_714916.3|ensembl:ENSG00000178202.14(gene)|ensembl:ENST00000323468.10(transcript)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0012505""(endomembrane system)|go:""GO:0018242""(protein O-linked glycosylation via serine)|go:""GO:0035251""(UDP-glucosyltransferase activity)|go:""GO:0035252""(UDP-xylosyltransferase activity)|go:""GO:0046527""(glucosyltransferase activity)|go:""GO:0140561""(EGF-domain serine glucosyltransferase activity)|go:""GO:0140562""(EGF-domain serine xylosyltransferase activity)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR006598(Lipopolysaccharide-modifying protein)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR051091|mint:Q7Z4H8|panther:PTHR12203(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3XlWUjmfq+NDal6gCnBKYz0x4wc632	rogid:utLTYC5qTbxTTVDlH7SQCOZUrH09606	intact-crc:7E5E2FD74E8DBDE3|rigid:gpZm67+HBncwNf3lOarHwxlWb0A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P22694	uniprotkb:Q8CZW5	intact:EBI-2679622|uniprotkb:Q59GC0|uniprotkb:Q5BNF2|uniprotkb:Q8IYR5|uniprotkb:Q14VH1|uniprotkb:Q5BNF3|uniprotkb:Q96B09|uniprotkb:Q8IZQ0|uniprotkb:Q5BNE9|uniprotkb:B4E2Q1|uniprotkb:Q7Z3M1|uniprotkb:Q5BNF1|uniprotkb:Q5CZ92|uniprotkb:Q5T1K3|uniprotkb:Q5BNF0|uniprotkb:B4DKB0|uniprotkb:B1APG4|ensembl:ENSP00000359723.2	intact:EBI-2866000	psi-mi:kapcb_human(display_long)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short)	psi-mi:q8czw5_yerpe(display_long)|uniprotkb:y3265(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866003|imex:IM-13779-7163	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:289""|ensembl:ENSG00000142875.21(gene)|ensembl:ENST00000370689.6(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003091""(renal water homeostasis)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004691""(cAMP-dependent protein kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0007188""(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034380""(high-density lipoprotein particle assembly)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070613""(regulation of protein processing)|go:""GO:0097546""(ciliary base)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P22694|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8963896|reactome:R-HSA-9010642|reactome:R-HSA-9634597|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9856530|refseq:NP_001229786.1|refseq:NP_001229787.1|refseq:NP_001229788.1|refseq:NP_001229789.1|refseq:NP_001229790.1|refseq:NP_001229791.1|refseq:NP_001287844.1|refseq:NP_001287845.1|refseq:NP_001287846.1|refseq:NP_002722.1|refseq:NP_891993.1|refseq:NP_997461.1|refseq:XP_005271076.1|refseq:XP_006710821.1|panther:PTHR24353(orthology-group)"	"interpro:IPR045455|interpro:IPR004968(DNA primase/nucleoside triphosphatase, C-terminal)|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014818(Phage/plasmid primase, P4, C-terminal)|interpro:IPR006171(TOPRIM)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR051620|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FEzsjRJZlkFu5+KK4abzu7oAY9E9606	rogid:9hTU+nEHzckJ+eR8MtLQy+R+Aqw632	intact-crc:887E94157A693FD1|rigid:z30coO4F9Vw1NktcgF3bnGGAdXs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P54819	uniprotkb:A0A2S9PM60	intact:EBI-1056291|uniprotkb:Q16856|uniprotkb:Q5TIF7|uniprotkb:Q8TCY2|uniprotkb:Q8TCY3|uniprotkb:A8K6L1|uniprotkb:B4DHH7|uniprotkb:B4DL64|uniprotkb:Q5EB54|ensembl:ENSP00000499935.1	intact:EBI-2853592|uniprotkb:Q74TV9|uniprotkb:Q0WEU8|uniprotkb:Q7CIL8|uniprotkb:A0A384KHN0	"psi-mi:kad2_human(display_long)|uniprotkb:AK2(gene name)|psi-mi:AK2(display_short)|uniprotkb:ADK2(gene name synonym)|uniprotkb:ATP-AMP transphosphorylase 2(gene name synonym)|uniprotkb:""ATP:AMP phosphotransferase""(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)"	psi-mi:a0a2s9pm60_yerpe(display_long)|uniprotkb:supX(gene name)|psi-mi:supX(display_short)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:topA(gene name synonym)|uniprotkb:YPO2218(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866029|imex:IM-13779-7167	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000004455.18(gene)|ensembl:ENST00000672715.1(transcript)|go:""GO:0004017""(adenylate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006172""(ADP biosynthetic process)|go:""GO:0015949""(nucleobase-containing small molecule interconversion)|go:""GO:0046033""(AMP metabolic process)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097226""(sperm mitochondrial sheath)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028587|interpro:IPR033690|mint:P54819|rcsb pdb:2C9Y|reactome:R-HSA-499943|refseq:NP_001186128.1|refseq:NP_001306068.1|refseq:NP_001306069.1|refseq:NP_001616.1|refseq:NP_037543.1|efo:""Orphanet:33355""|panther:PTHR23359(orthology-group)"	"interpro:IPR023406|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR023405|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR005733(DNA topoisomerase I, bacterial-type)|interpro:IPR013263(DNA topoisomerase I, zinc ribbon-like, bacterial-type)|interpro:IPR006171(TOPRIM)|refseq:WP_002210622.1|interpro:IPR034149|go:""GO:0003677""(DNA binding)|go:""GO:0003917""(""DNA topoisomerase type I (single strand cut, ATP-independent) activity"")|go:""GO:0005694""(chromosome)|go:""GO:0006265""(DNA topological change)|go:""GO:0046872""(metal ion binding)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR049330|interpro:IPR028612|refseq:YP_002347190.1|panther:PTHR42785(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pzIKBBzoytYPw3r87WMBueRNpWw9606	rogid:sBCN9yVi7vZQU8tykRnvKWsTra8632	intact-crc:1B24075A7916CDBB|rigid:C4qx7pJqMoeKRk8Et+8XDAaeN9U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00568	uniprotkb:Q8CZW4	intact:EBI-1044943|uniprotkb:Q9BVK9|uniprotkb:Q9UQC7|ensembl:ENSP00000362249.1|ensembl:ENSP00000494600.1	intact:EBI-2851384|uniprotkb:Q74QA0	"psi-mi:kad1_human(display_long)|uniprotkb:ATP-AMP transphosphorylase 1(gene name synonym)|uniprotkb:Myokinase(gene name synonym)|uniprotkb:AK1(gene name)|psi-mi:AK1(display_short)|uniprotkb:""ATP:AMP phosphotransferase""(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)"	psi-mi:q8czw4_yerpe(display_long)|uniprotkb:y3277(locus name)|uniprotkb:fldB(gene name)|psi-mi:fldB(display_short)|uniprotkb:YP_3589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866036|imex:IM-13779-7168	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:86817""|go:""GO:0070062""(extracellular exosome)|interpro:IPR000850(Adenylate kinase)|ensembl:ENSG00000106992.19(gene)|ensembl:ENST00000373156.5(transcript)|ensembl:ENST00000644144.2(transcript)|go:""GO:0001520""(outer dense fiber)|go:""GO:0004017""(adenylate kinase activity)|go:""GO:0004550""(nucleoside diphosphate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006172""(ADP biosynthetic process)|go:""GO:0009142""(nucleoside triphosphate biosynthetic process)|go:""GO:0015949""(nucleobase-containing small molecule interconversion)|go:""GO:0046033""(AMP metabolic process)|go:""GO:0046034""(ATP metabolic process)|go:""GO:0047506""(deoxyadenylate kinase activity)|interpro:IPR006267(Adenylate kinase, isozyme 1)|interpro:IPR027417|interpro:IPR028582|interpro:IPR033690|rcsb pdb:1Z83|rcsb pdb:2C95|rcsb pdb:7DE3|rcsb pdb:7X7S|reactome:R-HSA-499943|refseq:NP_000467.1|refseq:NP_001305050.1|refseq:XP_016869916.1|refseq:XP_016869917.1|panther:PTHR23359(orthology-group)"	"interpro:IPR029039|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001226(Flavodoxin, conserved site)|interpro:IPR010086(Flavodoxin, long chain)|go:""GO:0009055""(electron transfer activity)|go:""GO:0010181""(FMN binding)|interpro:IPR050619"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8Y034djIlviAtsKOQZj0TO89E+49606	rogid:FZlCLDczSf2Gjm4UsIPSSoGJH6E632	intact-crc:574EF2F90F64B934|rigid:B0I+8SRxuruVeIXtyX6kchw18Hc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:P17778	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2842665|uniprotkb:O68701	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866043|imex:IM-13779-7170	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:1F63FBD0AC68A2BB|rigid:a5n/qxGPHMToklQKjCqcBHDEC9Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZI61	uniprotkb:P13861	intact:EBI-2856600|uniprotkb:Q0WJ17|uniprotkb:Q8CZR9|uniprotkb:Q74RQ4	intact:EBI-2556122|uniprotkb:Q16823|intact:EBI-6116682|uniprotkb:Q9BUB1|intact:EBI-10961724|ensembl:ENSP00000265563.8|ensembl:ENSP00000394041.1|ensembl:ENSP00000516459.1	"psi-mi:glne_yerpe(display_long)|uniprotkb:glnE(gene name)|psi-mi:glnE(display_short)|uniprotkb:""ATP:glutamine synthetase adenylyltransferase""(gene name synonym)|uniprotkb:ATase(gene name synonym)|uniprotkb:YPO0653(locus name)|uniprotkb:YP_2968(locus name)|uniprotkb:y3525(locus name)"	psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866010|imex:IM-13779-7166	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023057|interpro:IPR005190(Glutamate-ammonia ligase adenylyltransferase)|interpro:IPR013546(GlnD PII-uridylyltransferase)|refseq:WP_002212194.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000820""(regulation of glutamine family amino acid metabolic process)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008882""([glutamate-ammonia-ligase] adenylyltransferase activity)|go:""GO:0047388""([glutamine synthetase]-adenylyl-L-tyrosine phosphorylase activity)|interpro:IPR043519|refseq:YP_002345721.1|panther:PTHR30621(orthology-group)"	"dip:DIP-552N|refseq:XP_011532244.1|refseq:NP_004148.1|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:XP_016862304.1|ensembl:ENSG00000114302.17(gene)|ensembl:ENST00000265563.13(transcript)|ensembl:ENST00000454963.5(transcript)|ensembl:ENST00000706574.1(transcript)|go:""GO:0004862""(cAMP-dependent protein kinase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0008603""(cAMP-dependent protein kinase regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030552""(cAMP binding)|go:""GO:0031588""(nucleotide-activated protein kinase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097546""(ciliary base)|go:""GO:0141162""(negative regulation of cAMP/PKA signal transduction)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR050503|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|rcsb pdb:8S8O|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9856530|panther:PTHR11635(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:RoEcJZfF/CSIgmtP9TYrZ6mEC70632	rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606	intact-crc:4BF06930619480E5|rigid:TnQB4YGznkAMJqKZ7GnH79d0KRo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q56993	uniprotkb:P31321	intact:EBI-2866017|uniprotkb:Q0WK27	intact:EBI-2805516|uniprotkb:Q8N422|ensembl:ENSP00000353415.4|ensembl:ENSP00000385349.1|ensembl:ENSP00000385749.1|ensembl:ENSP00000440449.1|ensembl:ENSP00000444487.1	psi-mi:hmuv_yerpe(display_long)|uniprotkb:hmuV(gene name)|psi-mi:hmuV(display_short)|uniprotkb:YPO0279(locus name)|uniprotkb:y0539(locus name)|uniprotkb:YP_0434(locus name)	psi-mi:kap1_human(display_long)|uniprotkb:PRKAR1B(gene name)|psi-mi:PRKAR1B(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866022|imex:IM-13779-7169	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002209058.1|dip:DIP-60001N|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|rcsb pdb:4G1U|refseq:YP_002345361.1|panther:PTHR42794(orthology-group)"	"ensembl:ENSG00000188191.16(gene)|ensembl:ENST00000360274.8(transcript)|ensembl:ENST00000403562.5(transcript)|ensembl:ENST00000406797.5(transcript)|ensembl:ENST00000537384.6(transcript)|ensembl:ENST00000544935.5(transcript)|go:""GO:0004862""(cAMP-dependent protein kinase inhibitor activity)|go:""GO:0005771""(multivesicular body)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0007611""(learning or memory)|go:""GO:0008603""(cAMP-dependent protein kinase regulator activity)|go:""GO:0030552""(cAMP binding)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0097546""(ciliary base)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098693""(regulation of synaptic vesicle cycle)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0141162""(negative regulation of cAMP/PKA signal transduction)|go:""GO:1900273""(positive regulation of long-term synaptic potentiation)|go:""GO:1903367""(positive regulation of fear response)|go:""GO:2000463""(positive regulation of excitatory postsynaptic potential)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR042818|interpro:IPR050503|mint:P31321|rcsb pdb:4DIN|rcsb pdb:4F9K|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9856530|refseq:NP_001158230.1|refseq:NP_001158231.1|refseq:NP_001158232.1|refseq:NP_001158233.1|refseq:NP_001158234.1|refseq:NP_002726.1|efo:""Orphanet:412066""|panther:PTHR11635(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eSUejgdkHLDqqKZW79roL+I/O80632	rogid:lHJ5CQLoIXsPDtmgJgb34zho6B89606	intact-crc:1BCECF9C73226418|rigid:GnPhnPEe2WapQ9b+rE27PKIoVfE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W0W1	uniprotkb:P01834	intact:EBI-2843417|uniprotkb:Q74X81|uniprotkb:Q0WBD9|uniprotkb:Q7CKJ7|uniprotkb:A0A2U2H033|uniprotkb:A0A384KHX8	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:a0a0h2w0w1_yerpe(display_long)|uniprotkb:YPO3510(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866071|imex:IM-13779-7172	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|go:""GO:0016020""(membrane)|refseq:WP_002210180.1|refseq:YP_002348399.1"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WAAPN9EE9NNNraWqy5ZHHVoV/5k632	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:B33EBCC80FDAA823|rigid:uv9UlwhqMxarMnppHaEq6ANLBGM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0D4	uniprotkb:P01834	intact:EBI-2847212	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:q8d0d4_yerpe(display_long)|uniprotkb:hmsH(gene name)|psi-mi:hmsH(display_short)|uniprotkb:y2359(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866057|imex:IM-13779-7171	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023870|interpro:IPR011990(Tetratricopeptide-like helical)|go:""GO:1901515""(poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity)|interpro:IPR049003"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oBs/IRM9/gKecuXNw9IoCZLu4Vw632	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:92636AF58B9FB039|rigid:KvyABTR4X7HgysZdNsscDuwKGlQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:Q8ZHK5	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2840092|uniprotkb:Q0WIF2	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:syk_yerpe(display_long)|uniprotkb:lysS(gene name)|psi-mi:lysS(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO0888(locus name)|uniprotkb:YP_3584(locus name)|uniprotkb:y3272(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866050|imex:IM-13779-7175	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR044136|go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|refseq:WP_002209930.1|interpro:IPR034762|refseq:YP_002345936.1|interpro:IPR045864|panther:PTHR42918(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:7RLsEIl+oAzL6AY+mxY4y8mj2AM632	intact-crc:17B5414B8BC02E56|rigid:O3ALJBTZ2oYaxmOduJeK4U8F8Pc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:Q7CKD4	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2840399|uniprotkb:Q74XT5	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:mtnn_yerpe(display_long)|uniprotkb:mtnN(gene name)|psi-mi:mtnN(display_short)|uniprotkb:5'-methylthioadenosine nucleosidase(gene name synonym)|uniprotkb:S-adenosylhomocysteine nucleosidase(gene name synonym)|uniprotkb:YPO3384(locus name)|uniprotkb:y0805(locus name)|uniprotkb:YP_0301(locus name)|uniprotkb:5'-deoxyadenosine nucleosidase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866078|imex:IM-13779-7173	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"interpro:IPR010049(MTA/SAH nucleosidase)|interpro:IPR000845(Nucleoside phosphorylase)|go:""GO:0005829""(cytosol)|go:""GO:0008782""(adenosylhomocysteine nucleosidase activity)|go:""GO:0008930""(methylthioadenosine nucleosidase activity)|go:""GO:0019284""(L-methionine salvage from S-adenosylmethionine)|go:""GO:0019509""(L-methionine salvage from methylthioadenosine)|go:""GO:0046124""(purine deoxyribonucleoside catabolic process)|refseq:WP_002209368.1|refseq:YP_002348276.1|interpro:IPR035994|panther:PTHR46832(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:B0ee2BpeZO6x/HS8F1N1G7fln3k632	intact-crc:FBC6875B549FA0CA|rigid:p5LPvWR+2r6YzKz+eoRaIwOQTfY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:Q8CWG4	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2856530|uniprotkb:Q74QZ9	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:q8cwg4_yerpe(display_long)|uniprotkb:glpD(gene name)|psi-mi:glpD(display_short)|uniprotkb:YP_3299(locus name)|uniprotkb:y3891(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866064|imex:IM-13779-7174	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR031656|go:""GO:0004368""(""glycerol-3-phosphate dehydrogenase (quinone) activity"")|go:""GO:0006072""(glycerol-3-phosphate metabolic process)|go:""GO:0009331""(""glycerol-3-phosphate dehydrogenase (FAD) complex"")|interpro:IPR038299|interpro:IPR036188"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:R9I22ZXVmXiKYYz/+NgwNjlHCb0632	intact-crc:B68C6FA28B9F4390|rigid:XarmINKhRiCtopFcAfeiGGdMe0A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:A0A5P8YAM6	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2844150|uniprotkb:Q7CFP2|uniprotkb:Q0W9V4	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:a0a5p8yam6_yerpe(display_long)|uniprotkb:malS(gene name)|psi-mi:malS(display_short)|uniprotkb:YPO4080(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866106|imex:IM-13779-7178	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"interpro:IPR014635(Alpha-amylase, MalS type)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209631.1|go:""GO:0004556""(alpha-amylase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0009313""(oligosaccharide catabolic process)|go:""GO:0030980""(alpha-glucan catabolic process)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348934.1|panther:PTHR10357(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:qjQekYtSF56tT51Uzp+xShmXohk632	intact-crc:CB13E2CFC720BFED|rigid:YfPS78zpGfMNvgk0NkRtGCzQwys	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H2S0	uniprotkb:P01834	intact:EBI-2845117|uniprotkb:Q74SK9|uniprotkb:Q0WCU8|uniprotkb:Q7CJE4|uniprotkb:A0A384LH60	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:a0a2u2h2s0_yerpe(display_long)|uniprotkb:dmsB(gene name)|psi-mi:dmsB(display_short)|uniprotkb:YPO2966(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866085|imex:IM-13779-7176	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR014297(Dimethylsulphoxide reductase, chain B)|interpro:IPR017900|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002211603.1|refseq:YP_002347890.1|interpro:IPR050954|panther:PTHR43177(orthology-group)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9jyIOCO41ainU3jSCjdpHqWlt50632	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:228A59D61E62667A|rigid:XJmBaF1qEgPi45BQXdajZ0XcLLs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:A0A5P8YJS7	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2863975|uniprotkb:Q0WJR4|uniprotkb:Q7CG38|uniprotkb:A0A384LPL9	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:a0a5p8yjs7_yerpe(display_long)|uniprotkb:YPO0397(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866099|imex:IM-13779-7177	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	interpro:IPR024534|interpro:IPR024537|interpro:IPR014544(Uncharacterized conserved protein UCP028408)|refseq:WP_002209174.1|refseq:YP_002345474.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:4d4c4vkH5Vwn3hSo6Gl3/NRs8lU632	intact-crc:D06B870909C1AF8B|rigid:lFk2zLM5jsQEhxdijYF7sKmCL1c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IYS2	uniprotkb:A0A5P8YCV0	intact:EBI-2866116|uniprotkb:Q8IVF8|uniprotkb:Q8NDI7|uniprotkb:Q5JXC1|uniprotkb:Q9BSY1|ensembl:ENSP00000365756.3	intact:EBI-2847775|uniprotkb:Q74Q84|uniprotkb:Q0WIC7|uniprotkb:Q7CGS8|uniprotkb:A0A384L1X8	psi-mi:k2013_human(display_long)|uniprotkb:KIAA2013(gene name)|psi-mi:KIAA2013(display_short)	psi-mi:a0a5p8ycv0_yerpe(display_long)|uniprotkb:YPO0913(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866113|imex:IM-13779-7180	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_612355.1|refseq:XP_005263588.1|ensembl:ENSG00000116685.17(gene)|ensembl:ENST00000376572.8(transcript)|go:""GO:0016020""(membrane)|interpro:IPR018795|mint:Q8IYS2|panther:PTHR31386(orthology-group)"	"interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|refseq:WP_002209955.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009396""(folic acid-containing compound biosynthetic process)|go:""GO:0030272""(5-formyltetrahydrofolate cyclo-ligase activity)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|interpro:IPR024185|interpro:IPR037171|refseq:YP_002345961.1|panther:PTHR23407(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:c98fgl75bIy0X3/+3fN4cVTgDY09606	rogid:10+1hunnZ1E8GkdgkFMuY64dDRY632	intact-crc:17A87AEDF7F670EC|rigid:tgXtmsE6NuQhB7NkhXqm+omMpmQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:Q0WHY6	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2843036|uniprotkb:Q74S50|uniprotkb:Q7CH18	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:q0why6_yerpe(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:YPO1059(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866092|imex:IM-13779-7179	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"interpro:IPR040982|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR029460|interpro:IPR048472|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0008408""(3'-5' exonuclease activity)|interpro:IPR041931|refseq:YP_002346102.1|interpro:IPR049821|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR32294(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:X+Qp61OuaTRp0k1p+Iszkh7DOUs632	intact-crc:33B4849D032059D7|rigid:uy3uhDm4Lv3h5XhhwUF5A9zl+sM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N163	uniprotkb:Q8D1M8	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|uniprotkb:B2RB79|uniprotkb:D3DSR6|ensembl:ENSP00000310670.4|ensembl:ENSP00000373930.3	intact:EBI-2843956	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	psi-mi:q8d1m8_yerpe(display_long)|uniprotkb:y0257(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866128|imex:IM-13779-7183	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066997.3|ensembl:ENSG00000158941.17(gene)|ensembl:ENST00000308511.9(transcript)|ensembl:ENST00000389279.7(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005819""(spindle)|go:""GO:0006397""(mRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0008380""(RNA splicing)|go:""GO:0009411""(response to UV)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032784""(regulation of DNA-templated transcription elongation)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0044609""(DBIRD complex)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048511""(rhythmic process)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090311""(regulation of protein deacetylation)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:2000003""(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR045353|interpro:IPR045354|mint:Q8N163|rcsb pdb:8EZ6|reactome:R-HSA-3371453|dip:DIP-38122N"	interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)|interpro:IPR050708	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	rogid:CV6eFVldIgYFQRKvjlqv9/IE4do632	intact-crc:2F6427E95A93FC5B|rigid:o5jRCVrfISbyZP8EYOgW9wvN3kw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P260	uniprotkb:A0A5P8YHK6	intact:EBI-2831057|ensembl:ENSP00000381198.2	intact:EBI-2856093|uniprotkb:A0A0H2W5D6|uniprotkb:Q74SI7|uniprotkb:Q7CJF5|uniprotkb:A0A384KU48	psi-mi:relch_human(display_long)|uniprotkb:RELCH(gene name)|psi-mi:RELCH(display_short)|uniprotkb:KIAA1468(gene name synonym)|uniprotkb:LisH domain and HEAT repeat-containing protein KIAA1468(gene name synonym)|uniprotkb:RAB11 binding and LisH domain, coiled-coil and HEAT repeat-containing(gene name synonym)|uniprotkb:RAB11-binding protein containing LisH, coiled-coil, and HEAT repeats(gene name synonym)	psi-mi:a0a5p8yhk6_yerpe(display_long)|uniprotkb:cysK(gene name)|psi-mi:cysK(display_short)|uniprotkb:cysZ(gene name synonym)|uniprotkb:YPO2992(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866135|imex:IM-13779-7181	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000134444.15(gene)|ensembl:ENST00000398130.6(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0055037""(recycling endosome)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040362|mint:Q9P260|refseq:NP_065905.2|refseq:NP_001333158.1|panther:PTHR32059(orthology-group)"	"interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR005856(Cysteine synthase K/M)|interpro:IPR005859(Cysteine synthase A)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR050214|refseq:WP_002222180.1|go:""GO:0004124""(cysteine synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006535""(cysteine biosynthetic process from serine)|go:""GO:0080146""(L-cysteine desulfhydrase activity)|interpro:IPR036052|refseq:YP_002347916.1|panther:PTHR10314(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ovvE1tbr12EJL4w5lDT6JxN77TI9606	rogid:UrC5dh7j9HnS/MZkY6/7kxZcpME632	intact-crc:581B83ADBAF2D489|rigid:N9hc2Ncyot+GZGPcZBQ52vWhR10	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A7E2V4	uniprotkb:Q7CIS2	intact:EBI-947995|uniprotkb:Q17RS8|uniprotkb:Q2TAB8|uniprotkb:Q6P439|uniprotkb:Q8IW81|uniprotkb:Q8NB34|uniprotkb:Q9H8F3|uniprotkb:O94987|uniprotkb:B2RP37|ensembl:ENSP00000474748.1	intact:EBI-2864684|uniprotkb:Q74TI4	psi-mi:zswm8_human(display_long)|uniprotkb:ZSWIM8(gene name)|psi-mi:ZSWIM8(display_short)|uniprotkb:KIAA0913(gene name synonym)	psi-mi:purr_yerpe(display_long)|uniprotkb:purR(gene name)|psi-mi:purR(display_short)|uniprotkb:Pur regulon repressor(gene name synonym)|uniprotkb:Purine nucleotide synthesis repressor(gene name synonym)|uniprotkb:YPO2387(locus name)|uniprotkb:y1950(locus name)|uniprotkb:YP_2173(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866161|imex:IM-13779-7184	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229416.1|refseq:NP_001229417.1|refseq:NP_055852.2|refseq:XP_006717788.1|ensembl:ENSG00000214655.11(gene)|ensembl:ENST00000605216.5(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0140958""(target-directed miRNA degradation)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|go:""GO:2000627""(positive regulation of miRNA catabolic process)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR048370|mint:A7E2V4|reactome:R-HSA-9010553|panther:PTHR22619(orthology-group)"	"interpro:IPR000843(Bacterial regulatory protein, LacI)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR023588|interpro:IPR028082|refseq:WP_002210943.1|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002347353.1|interpro:IPR046335|panther:PTHR30146(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:L/Zc7H24cEC7qtYp34nahN0pKEc9606	rogid:dzdla2mdqawR0H2DRHviks1p1L0632	intact-crc:2AD5646B1DCE9719|rigid:9zw0gZuG59yi9nf/8J6Dz+JVsR0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q32MH5	uniprotkb:A0A2U2GYT1	intact:EBI-2866142|uniprotkb:Q4G0R7|uniprotkb:Q32MH6|uniprotkb:Q5XJ16|uniprotkb:Q9P2H7|uniprotkb:Q9NV24|uniprotkb:A8KA52|uniprotkb:Q6PDA3|uniprotkb:B4DEP5|uniprotkb:B4DF40|uniprotkb:F5H8G0|ensembl:ENSP00000261844.7|ensembl:ENSP00000484641.1	intact:EBI-2850019|uniprotkb:Q74UX9|uniprotkb:A0A5P8YEY5|uniprotkb:A0A0H2W327|uniprotkb:Q7CHZ4|uniprotkb:A0A384L0J7	psi-mi:atosa_human(display_long)|uniprotkb:ATOSA(gene name)|psi-mi:ATOSA(display_short)|uniprotkb:FAM214A(gene name synonym)|uniprotkb:KIAA1370(gene name synonym)	psi-mi:a0a2u2gyt1_yerpe(display_long)|uniprotkb:fla AII.2(gene name)|psi-mi:fla AII.2(display_short)|uniprotkb:fla BII(gene name synonym)|uniprotkb:fliG(gene name synonym)|uniprotkb:YPO1829(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866154|imex:IM-13779-7182	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273424.1|refseq:XP_011520091.1|refseq:NP_062546.2|refseq:XP_005254604.1|refseq:XP_005254605.1|ensembl:ENSG00000047346.13(gene)|ensembl:ENST00000261844.11(transcript)|ensembl:ENST00000619572.5(transcript)|go:""GO:0005634""(nucleus)|interpro:IPR025261|interpro:IPR033473|interpro:IPR051506|mint:Q32MH5|panther:PTHR13199(orthology-group)"	"interpro:IPR023087|interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR028263|refseq:WP_002211142.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:YP_002346825.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MaU58q95wEB3FxQaY/ri5QKm06M9606	rogid:YBRmcuS18DJP2sfWEnw15dGyeYk632	intact-crc:3151B99749379E35|rigid:GGqyaVbron3TZJKavKKk/ToSx8I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60303	uniprotkb:Q0WDE1	intact:EBI-308314|uniprotkb:A7E2C2|ensembl:ENSP00000261588.4	intact:EBI-2848934|uniprotkb:Q74SY9|uniprotkb:Q8D0U7	psi-mi:katip_human(display_long)|uniprotkb:KATNIP(gene name)|psi-mi:KATNIP(display_short)|uniprotkb:KIAA0556(gene name synonym)	psi-mi:prmb_yerpe(display_long)|uniprotkb:prmB(gene name)|psi-mi:prmB(display_short)|uniprotkb:N5-glutamine methyltransferase PrmB(gene name synonym)|uniprotkb:YPO2750(locus name)|uniprotkb:YP_2413(locus name)|uniprotkb:y1584(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866175|imex:IM-13779-7185	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000047578.14(gene)|ensembl:ENST00000261588.10(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0042995""(cell projection)|go:""GO:0090660""(cerebrospinal fluid circulation)|interpro:IPR026704|interpro:IPR027859|refseq:NP_056017.3|efo:""Orphanet:475""|panther:PTHR21534(orthology-group)"	"interpro:IPR029063|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004556(Modification methylase HemK)|interpro:IPR017127(""Protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific"")|interpro:IPR007848(Methyltransferase small)|refseq:WP_002209710.1|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005829""(cytosol)|go:""GO:0032259""(methylation)|go:""GO:0036009""(protein-glutamine N-methyltransferase activity)|refseq:YP_002347697.1|panther:PTHR47806(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:z1fNJkYvQjuGUzF5VhrlSE1XIH89606	rogid:E0TcJR1cPqw7XzHhfs/tgH45UN8632	intact-crc:45D9ADD51B8749E1|rigid:MgJrzMnzEOZAqsYkztDeykh8weU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75071	uniprotkb:Q0WJT0	intact:EBI-2805635|uniprotkb:Q5SXB8|uniprotkb:D3DQ23|ensembl:ENSP00000361001.3	intact:EBI-2848005|uniprotkb:A0A3N4BBH4|uniprotkb:Q74XB0|uniprotkb:A0A0H2W350|uniprotkb:Q7CKL8|uniprotkb:A0A384LB40	psi-mi:efc14_human(display_long)|uniprotkb:EFCAB14(gene name)|psi-mi:EFCAB14(display_short)|uniprotkb:KIAA0494(gene name synonym)	psi-mi:q0wjt0_yerpe(display_long)|uniprotkb:rnr(gene name)|psi-mi:rnr(display_short)|uniprotkb:vacB(gene name synonym)|uniprotkb:YPO0380(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866182|imex:IM-13779-7188	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055589.1|ensembl:ENSG00000159658.15(gene)|ensembl:ENST00000371933.8(transcript)|go:""GO:0005509""(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR042352|panther:PTHR15717(orthology-group)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011805(Ribonuclease R, bacterial)|interpro:IPR013668(Ribonuclease R winged-helix domain)|interpro:IPR040476|refseq:WP_002209159.1|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008859""(exoribonuclease II activity)|go:""GO:0016070""(RNA metabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:YP_002345458.1|interpro:IPR050180"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UhD1cgnq+/XOmI2Y7LZ7ANpf9wA9606	rogid:jBGTi4O5QHZXkNIanuHOpATLT7Q632	intact-crc:36F23D54EAA6E02B|rigid:ZTWRLUuefg5EtgYp3FbeI4qeWik	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W5B3	uniprotkb:Q2KHM9	intact:EBI-2852094|uniprotkb:Q74US2|uniprotkb:A0A3N4BGG1|uniprotkb:Q0WG25|uniprotkb:Q7CHV7|uniprotkb:A0A384LL75	intact:EBI-2805604|uniprotkb:Q2KHN0|uniprotkb:Q9UG45|uniprotkb:O94853|uniprotkb:A8KA11|uniprotkb:B7Z479|uniprotkb:Q05D97|ensembl:ENSP00000355250.3	psi-mi:a0a0h2w5b3_yerpe(display_long)|uniprotkb:hpaH(gene name)|psi-mi:hpaH(display_short)|uniprotkb:hpcG(gene name synonym)|uniprotkb:YPO1766(locus name)	psi-mi:moonr_human(display_long)|uniprotkb:KIAA0753(gene name)|psi-mi:KIAA0753(display_short)|uniprotkb:MNR(gene name synonym)|uniprotkb:OFD1- and FOPNL-interacting protein(gene name synonym)|uniprotkb:OFIP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866168|imex:IM-13779-7189	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012690(2-oxo-hepta-3-ene-1,7-dioic acid hydratase)|refseq:WP_002211074.1|go:""GO:0009056""(catabolic process)|go:""GO:0018817""(2-oxo-hept-3-ene-1,7-dioate hydratase activity)|interpro:IPR036663|refseq:YP_002346763.1|interpro:IPR050772|interpro:IPR011234(Fumarylacetoacetase, C-terminal-related)"	"dip:DIP-61716N|efo:""Orphanet:2754""|efo:""Orphanet:474""|efo:""Orphanet:475""|ensembl:ENSG00000198920.11(gene)|ensembl:ENST00000361413.8(transcript)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0007099""(centriole replication)|go:""GO:0034451""(centriolar satellite)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0060271""(cilium assembly)|go:""GO:0061824""(cytosolic ciliogenesis)|go:""GO:0071539""(protein localization to centrosome)|interpro:IPR031447|mint:Q2KHM9|refseq:NP_055619.2|refseq:XP_006721675.1|refseq:XP_016880945.1|panther:PTHR15732(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/17	rogid:51nRlHF8JkFhYaUo6oPpqkEY8Ug632	rogid:3VyGPv3YYzpSoaCWulihyoxODOA9606	intact-crc:2E5759B6F64030A0|rigid:7sukAbd/lVcSc8oFVs92QiVG9ew	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43310	uniprotkb:A0A2U2H131	intact:EBI-2866189|uniprotkb:Q8IVD5|uniprotkb:B3KTR8|ensembl:ENSP00000256413.3|ensembl:ENSP00000489589.1	intact:EBI-2866195|uniprotkb:O68744|uniprotkb:Q74YP0|uniprotkb:A0A1U8QLK9|uniprotkb:Q7ARE6|uniprotkb:A0A384L1E1	psi-mi:ctif_human(display_long)|uniprotkb:KIAA0427(gene name synonym)|uniprotkb:CTIF(gene name)|psi-mi:CTIF(display_short)	psi-mi:a0a2u2h131_yerpe(display_long)|uniprotkb:YPMT1.26c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866199|imex:IM-13779-7186	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011524581.1|refseq:XP_006722650.1|refseq:XP_006722651.1|refseq:XP_006722652.1|refseq:NP_001135869.1|refseq:NP_055587.1|refseq:XP_016881591.1|ensembl:ENSG00000134030.14(gene)|ensembl:ENSG00000282825.2(gene)|ensembl:ENST00000256413.8(transcript)|ensembl:ENST00000635228.2(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0008494""(translation activator activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR051367|panther:PTHR23254(orthology-group)"	interpro:IPR016181(Acyl-CoA N-acyltransferase)|refseq:NP_395363.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H0bcuokEeCM2wBUa3OrE2/45zXc9606	rogid:1IY9/MFotY0aT3Swhxs1yHVxMYA632	intact-crc:B6318DF7AC17F191|rigid:gfW5Sw/yRGryXthET/L2KaJhbmI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZU52	uniprotkb:A0A6B3VCW6	intact:EBI-739493|uniprotkb:O43158|uniprotkb:Q5TF20|uniprotkb:Q7L2M2|uniprotkb:B3KRE5|uniprotkb:E1P573|ensembl:ENSP00000435150.2	intact:EBI-2846132	psi-mi:k0408_human(display_long)|uniprotkb:KIAA0408(gene name)|psi-mi:KIAA0408(display_short)	psi-mi:a0a6b3vcw6_yerpe(display_long)|uniprotkb:YP_3785(locus name)|uniprotkb:y3786(locus name)|uniprotkb:sbcC3(gene name)|psi-mi:sbcC3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866206|imex:IM-13779-7187	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_055517.3|ensembl:ENSG00000189367.15(gene)|ensembl:ENST00000483725.8(transcript)|interpro:IPR027882|mint:Q6ZU52|panther:PTHR15705(orthology-group)	uniprotkb:Q8CKB6(uniprot-removed-ac)|refseq:WP_002209173.1|interpro:IPR027417	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ys9F4yIzuccTYU42mOIlc/I4yYo9606	rogid:JAJQ2/SqTxwkVfzJ9zXmGfJ8osk632	intact-crc:0ECFD93698E68921|rigid:bDVVFFwMED36ciosDeSsQ5USNNs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CHU1	uniprotkb:Q92537	intact:EBI-2841165|uniprotkb:Q74V60	intact:EBI-2866213|ensembl:ENSP00000344424.4	psi-mi:mtfa_yerpe(display_long)|uniprotkb:mtfA(gene name)|psi-mi:mtfA(display_short)|uniprotkb:Probable zinc metallopeptidase MtfA(gene name synonym)|uniprotkb:YPO1732(locus name)|uniprotkb:YP_1472(locus name)|uniprotkb:y2576(locus name)	psi-mi:susd6_human(display_long)|uniprotkb:SUSD6(gene name)|psi-mi:SUSD6(display_short)|uniprotkb:DRAGO(gene name synonym)|uniprotkb:Drug-activated gene overexpressed protein(gene name synonym)|uniprotkb:KIAA0247(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866217|imex:IM-13779-7190	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002346732.1|interpro:IPR024079|interpro:IPR010384(Protein of unknown function DUF980)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|refseq:WP_002211042.1|interpro:IPR042252|panther:PTHR30164(orthology-group)"	"refseq:XP_011535714.1|refseq:NP_055549.1|refseq:XP_016877327.1|refseq:XP_016877328.1|ensembl:ENSG00000100647.8(gene)|ensembl:ENST00000342745.5(transcript)|go:""GO:0006974""(DNA damage response)|go:""GO:0016020""(membrane)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR042866|mint:Q92537|panther:PTHR46839(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3PKDmcLXdDD+p8B4M6novftNc7A632	rogid:Oq+pmp4Cgrao04MM3uvQV3a/HoA9606	intact-crc:46192F3C3AEA6A70|rigid:CCZvdr5/xiTDtW6YDWdHwSgqEv8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92617	uniprotkb:Q0W9Z9	intact:EBI-2866234|uniprotkb:O43332|uniprotkb:Q6PIE2|uniprotkb:Q6RH21|uniprotkb:Q6GMR1|uniprotkb:Q6P7T2|uniprotkb:Q504Q6|uniprotkb:Q59F29	intact:EBI-2844196|uniprotkb:Q74QS4|uniprotkb:Q7CFR7|uniprotkb:A0A3N4B6Z3|uniprotkb:A0A0H2W8Y1	psi-mi:npib3_human(display_long)|uniprotkb:NPIPB3(gene name)|psi-mi:NPIPB3(display_short)|uniprotkb:KIAA0220(gene name synonym)|uniprotkb:NPIPL3(gene name synonym)|uniprotkb:Nuclear pore complex-interacting protein-like 3(gene name synonym)|uniprotkb:Protein pps22-1(gene name synonym)	psi-mi:q0w9z9_yerpe(display_long)|uniprotkb:YPO4023(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866250|imex:IM-13779-7192	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR048893|interpro:IPR009443(Nuclear pore complex interacting)|go:""GO:0005635""(nuclear envelope)|go:""GO:0016020""(membrane)|interpro:IPR054697|reactome:R-HSA-9692916|panther:PTHR15438(orthology-group)"	"interpro:IPR000522(Bacterial transport system permease protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_002209582.1|interpro:IPR037294|refseq:YP_002348889.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kSRPDkniWJNsOVZ0yxSUAQ2owPQ9606	rogid:1FTJAJ0U6AAs9XCH+ROyaA+/JE4632	intact-crc:CD9E049386BDDDC2|rigid:yQa1AbeNl5OGrEh6vSKPhzOkHlc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P53990	uniprotkb:Q7ARD3	intact:EBI-945994|intact:EBI-4324656|uniprotkb:A8KAH5|uniprotkb:Q9BQ81|uniprotkb:Q9BWN2|uniprotkb:Q3SYM4|uniprotkb:J3QLU7	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:ist1_human(display_long)|uniprotkb:IST1(gene name)|psi-mi:IST1(display_short)|uniprotkb:Putative MAPK-activating protein PM28(gene name synonym)|uniprotkb:KIAA0174(gene name synonym)|uniprotkb:Charged multivesicular body protein 8(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866257|imex:IM-13779-7194	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055576.2|refseq:NP_001257904.1|refseq:NP_001257906.1|refseq:NP_001257905.1|refseq:NP_001257907.1|go:""GO:0000785""(chromatin)|go:""GO:0005576""(extracellular region)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0008104""(protein localization)|go:""GO:0015031""(protein transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030496""(midbody)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0048668""(collateral sprouting)|go:""GO:0048672""(positive regulation of collateral sprouting)|go:""GO:0051301""(cell division)|go:""GO:0061640""(cytoskeleton-dependent cytokinesis)|go:""GO:0061952""(midbody abscission)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090541""(MIT domain binding)|go:""GO:0090543""(Flemming body)|go:""GO:1904903""(ESCRT III complex disassembly)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|interpro:IPR042277|rcsb pdb:3FRR|rcsb pdb:3FRS|rcsb pdb:3JC1|rcsb pdb:4U7E|rcsb pdb:4U7I|rcsb pdb:4U7Y|rcsb pdb:4WZX|rcsb pdb:6E8G|rcsb pdb:6TZ4|rcsb pdb:6TZ5|rcsb pdb:6TZA|rcsb pdb:7S7J|rcsb pdb:8UC6|reactome:R-HSA-6798695|reactome:R-HSA-9668328|mint:P53990|dip:DIP-42546N|ensembl:ENST00000329908.12|ensembl:ENSP00000330408.8|ensembl:ENSG00000182149.21|ensembl:ENST00000378798.9|ensembl:ENSP00000368075.5|ensembl:ENST00000378799.11|ensembl:ENSP00000368076.6|ensembl:ENST00000535424.5|ensembl:ENSP00000438399.1|ensembl:ENST00000538850.5|ensembl:ENSP00000463711.1|ensembl:ENST00000541571.6|ensembl:ENSP00000455860.1|ensembl:ENST00000544564.5|ensembl:ENSP00000457844.1|ensembl:ENST00000606369.5|ensembl:ENSP00000475853.1|panther:PTHR12161(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RbWwKZ+sftO2x3UkFz8zAxVi2CU9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:546A39EA0F32A6ED|rigid:pTTRLrA3zbnHityKqCTOU+8+3N8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZY2	uniprotkb:Q92617	intact:EBI-2847648	intact:EBI-2866234|uniprotkb:O43332|uniprotkb:Q6PIE2|uniprotkb:Q6RH21|uniprotkb:Q6GMR1|uniprotkb:Q6P7T2|uniprotkb:Q504Q6|uniprotkb:Q59F29	psi-mi:q8czy2_yerpe(display_long)|uniprotkb:recC(gene name)|psi-mi:recC(display_short)|uniprotkb:Exonuclease V subunit RecC(gene name synonym)|uniprotkb:Helicase/nuclease RecBCD subunit RecC(gene name synonym)|uniprotkb:y3166(locus name)	psi-mi:npib3_human(display_long)|uniprotkb:NPIPB3(gene name)|psi-mi:NPIPB3(display_short)|uniprotkb:KIAA0220(gene name synonym)|uniprotkb:NPIPL3(gene name synonym)|uniprotkb:Nuclear pore complex-interacting protein-like 3(gene name synonym)|uniprotkb:Protein pps22-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866231|imex:IM-13779-7191	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002231332.1|interpro:IPR006697(Exodeoxyribonuclease V, RecC subunit)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0004519""(endonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008854""(exodeoxyribonuclease V activity)|go:""GO:0009338""(exodeoxyribonuclease V complex)|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR041500"	"interpro:IPR048893|interpro:IPR009443(Nuclear pore complex interacting)|go:""GO:0005635""(nuclear envelope)|go:""GO:0016020""(membrane)|interpro:IPR054697|reactome:R-HSA-9692916|panther:PTHR15438(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2Q4GsXvIqa5TrZjFD/kPigwGJNw632	rogid:kSRPDkniWJNsOVZ0yxSUAQ2owPQ9606	intact-crc:6FAA80F36E2D6FC4|rigid:8cuWA7t9R8jsmtRJdWjgqRN0m6I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W2N9	uniprotkb:Q6AI39	intact:EBI-2840467|uniprotkb:Q74XT4|uniprotkb:Q0WBR4|uniprotkb:A0A384L498|uniprotkb:Q7CKD3|uniprotkb:A0A3N4B9W7	intact:EBI-1012434|uniprotkb:Q5TFZ3|uniprotkb:Q92514|uniprotkb:A1L3W2|ensembl:ENSP00000313933.4|ensembl:ENSP00000377723.1	psi-mi:a0a0h2w2n9_yerpe(display_long)|uniprotkb:degP(gene name)|psi-mi:degP(display_short)|uniprotkb:gsrA(gene name synonym)|uniprotkb:htrA(gene name synonym)|uniprotkb:ptd(gene name synonym)|uniprotkb:YPO3382(locus name)	psi-mi:bicrl_human(display_long)|uniprotkb:BICRAL(gene name)|psi-mi:BICRAL(display_short)|uniprotkb:GLTSCR1L(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 1 protein-like(gene name synonym)|uniprotkb:KIAA0240(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866224|imex:IM-13779-7193	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:WP_002209370.1|refseq:YP_002348274.1|interpro:IPR036034"	"refseq:NP_056164.1|refseq:NP_001305748.1|ensembl:ENSG00000112624.14(gene)|ensembl:ENST00000314073.10(transcript)|ensembl:ENST00000394168.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140288""(GBAF complex)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR015671(Glioma tumour suppressor candidate region gene 1)|interpro:IPR052438|panther:PTHR15572(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wh5TqHAdstARdvvFDyS2kqzSnxY632	rogid:wmf9lC4nRlhlduBaz3ZPV8ro3vQ9606	intact-crc:C00641078A0A3732|rigid:WGSkvSyHm7BnChbqH4OtD6GACng	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H9V9	uniprotkb:A0A2S9PBP0	intact:EBI-2866290|uniprotkb:A0A087WT84|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000477669.1	intact:EBI-2843228|uniprotkb:Q74PK6|uniprotkb:Q7CL58|uniprotkb:A0A3N4BAA7|uniprotkb:A0A0H2WA10	psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym)	psi-mi:a0a2s9pbp0_yerpe(display_long)|uniprotkb:YPO3648(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866297|imex:IM-13779-7198	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692.13(gene)|ensembl:ENST00000620518.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016706""(2-oxoglutarate-dependent dioxygenase activity)|go:""GO:0018126""(protein hydroxylation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045905""(positive regulation of translational termination)|go:""GO:0046872""(metal ion binding)|go:""GO:0106156""(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR050910|mint:Q9H9V9|reactome:R-HSA-9629569|panther:PTHR12480(orthology-group)"	"interpro:IPR015815(3-hydroxyacid dehydrogenase/reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR002204(3-hydroxyisobutyrate dehydrogenase-related, conserved site)|interpro:IPR029154|refseq:WP_002210056.1|go:""GO:0016054""(organic acid catabolic process)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|interpro:IPR036291|refseq:YP_002348533.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hAXcGZn80VrybPlXvuvkHGqPf4A9606	rogid:aYeaLvaUeXHyF5tQMvpaMGoy1ME632	intact-crc:4F287F683C1DAA1C|rigid:BcVa8BCvTtw34fX4OJBrX6GVexI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15018	uniprotkb:A0A0H2W225	intact:EBI-1056583|uniprotkb:Q96H11|uniprotkb:B4DKR2|ensembl:ENSP00000298492.5|intact:EBI-28981592	intact:EBI-2844774	psi-mi:abrx2_human(display_long)|uniprotkb:ABRAXAS2(gene name)|psi-mi:ABRAXAS2(display_short)|uniprotkb:ABRO1(gene name synonym)|uniprotkb:Abraxas brother protein 1(gene name synonym)|uniprotkb:FAM175B(gene name synonym)|uniprotkb:KIAA0157(gene name synonym)|uniprotkb:Protein FAM175B(gene name synonym)	psi-mi:a0a0h2w225_yerpe(display_long)|uniprotkb:sbcC2(gene name)|psi-mi:sbcC2(display_short)|uniprotkb:sbcC(gene name synonym)|uniprotkb:YP_0725(locus name)|uniprotkb:y0976(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866264|imex:IM-13779-7197	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_115558.3|ensembl:ENSG00000165660.8(gene)|ensembl:ENST00000298492.6(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000922""(spindle pole)|go:""GO:0002931""(response to ischemia)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0007059""(chromosome segregation)|go:""GO:0008017""(microtubule binding)|go:""GO:0008608""(attachment of spindle microtubules to kinetochore)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0051301""(cell division)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0070552""(BRISC complex)|go:""GO:0090307""(mitotic spindle assembly)|interpro:IPR023238|interpro:IPR023240|interpro:IPR037518|mint:Q15018|rcsb pdb:6H3C|rcsb pdb:6R8F|reactome:R-HSA-5689901|panther:PTHR31728(orthology-group)"	"interpro:IPR027417|interpro:IPR038729|uniprotkb:A0A6B3T1W4(uniprot-removed-ac)|go:""GO:0004527""(exonuclease activity)|go:""GO:0006302""(double-strand break repair)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002223265.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fYZdQpH09qcBBUV1IKV2wsRk4m89606	rogid:kLIIS2zCAycudIvZsl7pSdsTqz0632	intact-crc:92B71C1CF13628FC|rigid:mcc2Of618XP24XJh4norMLJbcU8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZGV2	uniprotkb:P17275	intact:EBI-2866278|uniprotkb:Q0WHM5	intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315.4	psi-mi:dusc_yerpe(display_long)|uniprotkb:dusC(gene name)|psi-mi:dusC(display_short)|uniprotkb:U16-specific dihydrouridine synthase(gene name synonym)|uniprotkb:tRNA-dihydrouridine synthase C(gene name synonym)|uniprotkb:YPO1175(locus name)|uniprotkb:YP_0963(locus name)|uniprotkb:y3015(locus name)	psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short)|uniprotkb:Transcription factor AP-1 subunit JunB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866283|imex:IM-13779-7196	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR042270|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR001269(Dihydrouridine synthase, DuS)|interpro:IPR018517|interpro:IPR032886|interpro:IPR035587|go:""GO:0000049""(tRNA binding)|go:""GO:0010181""(FMN binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0102262""(tRNA-dihydrouridine16 synthase activity)|refseq:WP_002228612.1|refseq:YP_002346213.1|panther:PTHR11082(orthology-group)"	"refseq:NP_002220.1|ensembl:ENSG00000171223.6(gene)|ensembl:ENST00000302754.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001829""(trophectodermal cell differentiation)|go:""GO:0002158""(osteoclast proliferation)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0033687""(osteoblast proliferation)|go:""GO:0035976""(transcription factor AP-1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046697""(decidualization)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060136""(embryonic process involved in female pregnancy)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000319""(regulation of T-helper 17 cell differentiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR050946|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|reactome:R-HSA-9725371|dip:DIP-1052N|panther:PTHR11462(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/07	rogid:vnQDJrziG4Yk8B2+Ye/AO2yCjak632	rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606	intact-crc:21D056C9B2AFE8E9|rigid:dtk0Lf2g0A5ehCMWJMdmz9rGSCc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P05412	uniprotkb:Q8D008	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1	intact:EBI-2841189|uniprotkb:Q74WC8	psi-mi:jun_human(display_long)|uniprotkb:Transcription factor AP-1 subunit Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	psi-mi:q8d008_yerpe(display_long)|uniprotkb:livM2(gene name)|psi-mi:livM2(display_short)|uniprotkb:YP_0948(locus name)|uniprotkb:y3001(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866271|imex:IM-13779-7195	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002219.1|panther:PTHR11462(orthology-group)|ensembl:ENSG00000177606.9(gene)|ensembl:ENST00000371222.4(transcript)|ensembl:ENST00000678696.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0019046""(release from viral latency)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035976""(transcription factor AP-1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR050946|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|rcsb pdb:8SOS|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324|reactome:R-HSA-9725370|dip:DIP-5961N|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1"	"interpro:IPR001851(Bacterial inner-membrane translocator)|interpro:IPR017779(ABC transporter, urea, permease protein, UrtB)|interpro:IPR016024(Armadillo-type fold)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR052157"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	rogid:f8uYuwhgruoNpYu1MdwJpc91v5Q632	intact-crc:B2515885501F86FE|rigid:pNtkchRbbIqy/HTT3tA0oVkLg8U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZEK1	uniprotkb:P23458	intact:EBI-2844117|uniprotkb:Q0WEZ9	intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204.4|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000500485.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000500841.1|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1	psi-mi:seld_yerpe(display_long)|uniprotkb:selD(gene name)|psi-mi:selD(display_short)|uniprotkb:Selenium donor protein(gene name synonym)|uniprotkb:Selenophosphate synthase(gene name synonym)|uniprotkb:YPO2164(locus name)|uniprotkb:y2157(locus name)|uniprotkb:YP_1964(locus name)	psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866332|imex:IM-13779-7204	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR016188(PurM, N-terminal-like)|interpro:IPR004536(Selenide water dikinase)|interpro:IPR023061|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004756""(selenide, water dikinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016260""(selenocysteine biosynthetic process)|interpro:IPR036676|interpro:IPR036921|refseq:WP_002211671.1|refseq:YP_002347139.1|panther:PTHR10256(orthology-group)"	"ensembl:ENSG00000162434.14(gene)|ensembl:ENST00000342505.5(transcript)|ensembl:ENST00000671929.2(transcript)|ensembl:ENST00000671954.2(transcript)|ensembl:ENST00000672179.2(transcript)|ensembl:ENST00000672247.2(transcript)|ensembl:ENST00000672434.2(transcript)|ensembl:ENST00000672751.2(transcript)|ensembl:ENST00000699262.1(transcript)|ensembl:ENST00000699312.1(transcript)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005131""(growth hormone receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038196""(type III interferon-mediated signaling pathway)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046872""(metal ion binding)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|interpro:IPR051286|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|rcsb pdb:8EXJ|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9732724|reactome:R-HSA-9833109|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|refseq:NP_001308785.1|refseq:NP_002218.2|dip:DIP-133N|panther:PTHR45807(orthology-group)|efo:""Orphanet:574957""|efo:""Orphanet:667662""|ensembl:ENSP00000343204.4|ensembl:ENSP00000500485.1|ensembl:ENSP00000500841.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:0PvbxC5hrS69R+2dvJKBMQAdp0g632	rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606	intact-crc:BAEF27DB885376AB|rigid:tdgsbiRr8yNvnyDPqeKeWcwSvus	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P23458	uniprotkb:Q8ZJP8	intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204.4|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000500485.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000500841.1|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1	intact:EBI-2847365|uniprotkb:Q0WKP8	psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym)	psi-mi:rnph_yerpe(display_long)|uniprotkb:rph(gene name)|psi-mi:rph(display_short)|uniprotkb:tRNA nucleotidyltransferase(gene name synonym)|uniprotkb:YPO0044(locus name)|uniprotkb:y0097(locus name)|uniprotkb:YP_0045(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866339|imex:IM-13779-7202	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000162434.14(gene)|ensembl:ENST00000342505.5(transcript)|ensembl:ENST00000671929.2(transcript)|ensembl:ENST00000671954.2(transcript)|ensembl:ENST00000672179.2(transcript)|ensembl:ENST00000672247.2(transcript)|ensembl:ENST00000672434.2(transcript)|ensembl:ENST00000672751.2(transcript)|ensembl:ENST00000699262.1(transcript)|ensembl:ENST00000699312.1(transcript)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005131""(growth hormone receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038196""(type III interferon-mediated signaling pathway)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046872""(metal ion binding)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|interpro:IPR051286|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|rcsb pdb:8EXJ|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9732724|reactome:R-HSA-9833109|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|refseq:NP_001308785.1|refseq:NP_002218.2|dip:DIP-133N|panther:PTHR45807(orthology-group)|efo:""Orphanet:574957""|efo:""Orphanet:667662""|ensembl:ENSP00000343204.4|ensembl:ENSP00000500485.1|ensembl:ENSP00000500841.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1"	"interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR002381(Ribonuclease phosphorolytic, bacterial-type)|interpro:IPR018336|interpro:IPR027408|refseq:WP_002208997.1|go:""GO:0000049""(tRNA binding)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0003723""(RNA binding)|go:""GO:0006364""(rRNA processing)|go:""GO:0008033""(tRNA processing)|go:""GO:0009022""(tRNA nucleotidyltransferase activity)|go:""GO:0016075""(rRNA catabolic process)|interpro:IPR036345|refseq:YP_002345140.1|interpro:IPR050080|panther:PTHR11953(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606	rogid:w1ahukqHBCGll+OW4Q9GEEimgOY632	intact-crc:8C1DF8DB8AEFBC65|rigid:xArzFqyA9cXzjNic3+A4Vepta1U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PLF9	uniprotkb:Q9Y2K7	intact:EBI-2841354|uniprotkb:Q74X44|uniprotkb:Q0WBI4|uniprotkb:Q7CKG9|uniprotkb:A0A380PH15	intact:EBI-765758|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|ensembl:ENSP00000432786.1|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55	psi-mi:a0a2s9plf9_yerpe(display_long)|uniprotkb:phnP(gene name)|psi-mi:phnP(display_short)|uniprotkb:YPO3465(locus name)	psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866311|imex:IM-13779-7199	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001279(Beta-lactamase-like)|interpro:IPR017693(Phosphonate metabolism protein PhnP)|go:""GO:0008081""(phosphoric diester hydrolase activity)|go:""GO:0019700""(organic phosphonate catabolic process)|refseq:WP_002209284.1|refseq:YP_002348354.1|interpro:IPR035682|interpro:IPR036866|interpro:IPR050419"	"refseq:NP_036440.1|refseq:NP_001243334.1|ensembl:ENSG00000173120.15(gene)|ensembl:ENST00000529006.7(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0032452""(histone demethylase activity)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0045322""(unmethylated CpG binding)|go:""GO:0051864""(histone H3K36 demethylase activity)|go:""GO:0140680""(histone H3K36me/H3K36me2 demethylase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR050690|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:7UV9|reactome:R-HSA-3214842|refseq:XP_011543163.1|dip:DIP-34596N|panther:PTHR23123(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/22	rogid:inlYtqvN2O/ToeHxbyY8+4PwJr0632	rogid:FWcxfQykne+IrmtpDxZ218sEURc9606	intact-crc:47722D61F0485233|rigid:1ZaEVzzVUL/OM641eiS10DbuUoM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86YT9	uniprotkb:P68587	intact:EBI-2816560|uniprotkb:Q496M1|uniprotkb:Q8NF70|uniprotkb:Q8N9I7|uniprotkb:Q7Z499|uniprotkb:B0YIV1|uniprotkb:B0YIV2|uniprotkb:Q5DTC6|ensembl:ENSP00000348635.5	intact:EBI-2844901|uniprotkb:P40295	psi-mi:jaml_human(display_long)|uniprotkb:JAML(gene name)|psi-mi:JAML(display_short)|uniprotkb:AMICA1(gene name synonym)|uniprotkb:Adhesion molecule interacting with CXADR antigen 1(gene name synonym)|uniprotkb:Dendritic cell-specific protein CREA7-1(gene name synonym)|uniprotkb:UNQ722/PRO1387(orf name)	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866318|imex:IM-13779-7201	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273500.1|refseq:NP_001091996.1|refseq:NP_694938.2|refseq:NP_001273499.1|ensembl:ENSG00000160593.20(gene)|ensembl:ENST00000356289.10(transcript)|go:""GO:0001518""(voltage-gated sodium channel complex)|go:""GO:0005178""(integrin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0035696""(monocyte extravasation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046629""(gamma-delta T cell activation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0060054""(positive regulation of epithelial cell proliferation involved in wound healing)|go:""GO:0072672""(neutrophil extravasation)|interpro:IPR000920(Myelin P0 protein)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-202733|panther:PTHR13869(orthology-group)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YIYLdTPIX+q/c0mPOTVUhT0vNUA9606	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	intact-crc:63C9160D40E2A34C|rigid:xNfL6a1DG6WpucjN5pMdM2ozxMk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60271	uniprotkb:Q8ZED8	intact:EBI-1023301|uniprotkb:A6H8U5|intact:EBI-2560890|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|ensembl:ENSP00000262013.7	intact:EBI-2840186|uniprotkb:Q0WET1	psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym)	psi-mi:rnb_yerpe(display_long)|uniprotkb:rnb(gene name)|psi-mi:rnb(display_short)|uniprotkb:Exoribonuclease II(gene name synonym)|uniprotkb:YPO2235(locus name)|uniprotkb:y2077(locus name)|uniprotkb:YP_2034(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866304|imex:IM-13779-7203	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294.22(gene)|ensembl:ENST00000262013.12(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019894""(kinesin binding)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032418""(lysosome localization)|go:""GO:0034451""(centriolar satellite)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903860""(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|panther:PTHR13886(orthology-group)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR022966|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011804(Ribonuclease II, bacterial)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008859""(exoribonuclease II activity)|refseq:WP_002210605.1|interpro:IPR001900(Ribonuclease II and R)|refseq:YP_002347207.1|interpro:IPR050180|panther:PTHR23355(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UsItS/q6arsUKVnp+hGuBZE3P809606	rogid:8bPsungEsr2YreZsZg9IgHPm9uI632	intact-crc:C76D7A2F81D41DA0|rigid:d5ZPWXKTgF+kSf5Ay+uRS4eUf+Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H346	uniprotkb:Q86YT9	intact:EBI-2849136|uniprotkb:Q74TG8|uniprotkb:A0A0H2W5H4|uniprotkb:Q0WEC0|uniprotkb:Q7CIT1|uniprotkb:A0A384KWM5	intact:EBI-2816560|uniprotkb:Q496M1|uniprotkb:Q8NF70|uniprotkb:Q8N9I7|uniprotkb:Q7Z499|uniprotkb:B0YIV1|uniprotkb:B0YIV2|uniprotkb:Q5DTC6|ensembl:ENSP00000348635.5	psi-mi:a0a2u2h346_yerpe(display_long)|uniprotkb:YPO2403(locus name)	psi-mi:jaml_human(display_long)|uniprotkb:JAML(gene name)|psi-mi:JAML(display_short)|uniprotkb:AMICA1(gene name synonym)|uniprotkb:Adhesion molecule interacting with CXADR antigen 1(gene name synonym)|uniprotkb:Dendritic cell-specific protein CREA7-1(gene name synonym)|uniprotkb:UNQ722/PRO1387(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866325|imex:IM-13779-7200	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010231(SUF system FeS cluster assembly, SufB)|interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|refseq:WP_002211808.1|go:""GO:0016226""(iron-sulfur cluster assembly)|interpro:IPR037284|refseq:YP_002347368.1|interpro:IPR045595"	"refseq:NP_001273500.1|refseq:NP_001091996.1|refseq:NP_694938.2|refseq:NP_001273499.1|ensembl:ENSG00000160593.20(gene)|ensembl:ENST00000356289.10(transcript)|go:""GO:0001518""(voltage-gated sodium channel complex)|go:""GO:0005178""(integrin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0035696""(monocyte extravasation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046629""(gamma-delta T cell activation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0060054""(positive regulation of epithelial cell proliferation involved in wound healing)|go:""GO:0072672""(neutrophil extravasation)|interpro:IPR000920(Myelin P0 protein)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-202733|panther:PTHR13869(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DkCekEHB1T0D0zddmetEadbmVDk632	rogid:YIYLdTPIX+q/c0mPOTVUhT0vNUA9606	intact-crc:F199768E67BCEA18|rigid:9Qu4+nDwlS8KedeTz/GB+X7s2Rw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P78504	uniprotkb:Q8ZCW0	intact:EBI-2847071|uniprotkb:O14902|uniprotkb:A0AV43|uniprotkb:O15122|uniprotkb:Q15816|uniprotkb:B4DYR1|uniprotkb:E9PCF9|ensembl:ENSP00000254958.4	intact:EBI-2842923|uniprotkb:Q7CJK9|uniprotkb:Q0WD52|uniprotkb:Q74SA7	psi-mi:jag1_human(display_long)|uniprotkb:JAG1(gene name)|psi-mi:JAG1(display_short)|uniprotkb:JAGL1(gene name synonym)	psi-mi:mdtb_yerpe(display_long)|uniprotkb:mdtB(gene name)|psi-mi:mdtB(display_short)|uniprotkb:Multidrug transporter MdtB(gene name synonym)|uniprotkb:YPO2848(locus name)|uniprotkb:y1385(locus name)|uniprotkb:YP_2715(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866373|imex:IM-13779-7206	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000101384.12(gene)|ensembl:ENST00000254958.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001709""(cell fate determination)|go:""GO:0001953""(negative regulation of cell-matrix adhesion)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002011""(morphogenesis of an epithelial sheet)|go:""GO:0002085""(inhibition of neuroepithelial cell differentiation)|go:""GO:0002456""(T cell mediated immunity)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003215""(cardiac right ventricle morphogenesis)|go:""GO:0005112""(Notch binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005543""(phospholipid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008083""(growth factor activity)|go:""GO:0016020""(membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0022408""(negative regulation of cell-cell adhesion)|go:""GO:0030097""(hemopoiesis)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0035909""(aorta morphogenesis)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042491""(inner ear auditory receptor cell differentiation)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045446""(endothelial cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045602""(negative regulation of endothelial cell differentiation)|go:""GO:0045639""(positive regulation of myeloid cell differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050678""(regulation of epithelial cell proliferation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0061073""(ciliary body morphogenesis)|go:""GO:0061101""(neuroendocrine cell differentiation)|go:""GO:0061156""(pulmonary artery morphogenesis)|go:""GO:0061309""(cardiac neural crest cell development involved in outflow tract morphogenesis)|go:""GO:0061444""(endocardial cushion cell development)|go:""GO:0062043""(positive regulation of cardiac epithelial to mesenchymal transition)|go:""GO:0072006""(nephron development)|go:""GO:0072015""(podocyte development)|go:""GO:0072017""(distal tubule development)|go:""GO:0072070""(loop of Henle development)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:2000737""(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001774(""Delta/Serrate/lag-2 (DSL) protein"")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026219|interpro:IPR049883|mint:P78504|rcsb pdb:2KB9|rcsb pdb:2VJ2|rcsb pdb:4CBZ|rcsb pdb:4CC0|rcsb pdb:4CC1|rcsb pdb:4XI7|rcsb pdb:5BO1|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-8941856|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9013507|reactome:R-HSA-9013700|reactome:R-HSA-9831926|refseq:NP_000205.1|refseq:XP_016883196.1|dip:DIP-46371N|efo:""Orphanet:261600""|efo:""Orphanet:261619""|efo:""Orphanet:3303""|panther:PTHR24044(orthology-group)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR022831|interpro:IPR027463|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:WP_002209793.1|refseq:YP_002347786.1|panther:PTHR32063(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/08	rogid:kaBPZjsO7mchlR6vYIknqvTluos9606	rogid:LHw1WKWrAW5/xlsQ5C6WVb5Ua3M632	intact-crc:818182F193F57F39|rigid:9wxduCZhaEx0MRHKuF4Nem4m70A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P23458	uniprotkb:A0A5P8YAV0	intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204.4|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000500485.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000500841.1|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1	intact:EBI-2840652|uniprotkb:Q74RB8|uniprotkb:A0A0H2W750|uniprotkb:A0A384KV61|uniprotkb:Q7CL03	psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym)	psi-mi:a0a5p8yav0_yerpe(display_long)|uniprotkb:ilvG(gene name)|psi-mi:ilvG(display_short)|uniprotkb:YPO3901(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866346|imex:IM-13779-7205	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000162434.14(gene)|ensembl:ENST00000342505.5(transcript)|ensembl:ENST00000671929.2(transcript)|ensembl:ENST00000671954.2(transcript)|ensembl:ENST00000672179.2(transcript)|ensembl:ENST00000672247.2(transcript)|ensembl:ENST00000672434.2(transcript)|ensembl:ENST00000672751.2(transcript)|ensembl:ENST00000699262.1(transcript)|ensembl:ENST00000699312.1(transcript)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005131""(growth hormone receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038196""(type III interferon-mediated signaling pathway)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046872""(metal ion binding)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|interpro:IPR051286|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|rcsb pdb:8EXJ|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9732724|reactome:R-HSA-9833109|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|refseq:NP_001308785.1|refseq:NP_002218.2|dip:DIP-133N|panther:PTHR45807(orthology-group)|efo:""Orphanet:574957""|efo:""Orphanet:667662""|ensembl:ENSP00000343204.4|ensembl:ENSP00000500485.1|ensembl:ENSP00000500841.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1"	"interpro:IPR039368|interpro:IPR012846(Acetolactate synthase, large subunit, biosynthetic)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR000399(TPP-binding enzymes, conserved site)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003984""(acetolactate synthase activity)|go:""GO:0005948""(acetolactate synthase complex)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR029035|interpro:IPR029061|refseq:WP_002212017.1|refseq:YP_002348776.1|interpro:IPR045229|panther:PTHR18968(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606	rogid:XazbqAGNZAxmz6MG/dmejOvmdYE632	intact-crc:EC524FDB9858794B|rigid:pRvOF13AjGy0HyOIlVVy4wMgzBg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAR2	uniprotkb:P23458	intact:EBI-2842016|uniprotkb:Q0WAS9	intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204.4|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000500485.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000500841.1|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1	psi-mi:pur2_yerpe(display_long)|uniprotkb:purD(gene name)|psi-mi:purD(display_short)|uniprotkb:GARS(gene name synonym)|uniprotkb:Glycinamide ribonucleotide synthetase(gene name synonym)|uniprotkb:Phosphoribosylglycinamide synthetase(gene name synonym)|uniprotkb:YPO3729(locus name)|uniprotkb:y0501(locus name)|uniprotkb:YP_3092(locus name)	psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866353|imex:IM-13779-7208	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|rcsb pdb:3MJF|go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_002210691.1|interpro:IPR037123|refseq:YP_002348609.1|panther:PTHR43472(orthology-group)"	"ensembl:ENSG00000162434.14(gene)|ensembl:ENST00000342505.5(transcript)|ensembl:ENST00000671929.2(transcript)|ensembl:ENST00000671954.2(transcript)|ensembl:ENST00000672179.2(transcript)|ensembl:ENST00000672247.2(transcript)|ensembl:ENST00000672434.2(transcript)|ensembl:ENST00000672751.2(transcript)|ensembl:ENST00000699262.1(transcript)|ensembl:ENST00000699312.1(transcript)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005131""(growth hormone receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038196""(type III interferon-mediated signaling pathway)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046872""(metal ion binding)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|interpro:IPR051286|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|rcsb pdb:8EXJ|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9732724|reactome:R-HSA-9833109|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|refseq:NP_001308785.1|refseq:NP_002218.2|dip:DIP-133N|panther:PTHR45807(orthology-group)|efo:""Orphanet:574957""|efo:""Orphanet:667662""|ensembl:ENSP00000343204.4|ensembl:ENSP00000500485.1|ensembl:ENSP00000500841.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:lCNHTp0WZiZKDpeBBaNkuNmlzIc632	rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606	intact-crc:DB73E3DB88B102A0|rigid:H6OmGRh8csyUgzt1HIJ5j5/vgUI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WAP4	uniprotkb:P23458	intact:EBI-2866363|uniprotkb:Q8D1H7|uniprotkb:Q74R11	intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204.4|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000500485.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000500841.1|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1	psi-mi:pepq_yerpe(display_long)|uniprotkb:pepQ(gene name)|psi-mi:pepQ(display_short)|uniprotkb:Imidodipeptidase(gene name synonym)|uniprotkb:Proline dipeptidase(gene name synonym)|uniprotkb:YPO3765(locus name)|uniprotkb:y0465(locus name)|uniprotkb:YP_3283(locus name)	psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866360|imex:IM-13779-7207	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR048819|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|interpro:IPR022846|interpro:IPR036005|refseq:WP_002211547.1|interpro:IPR029149|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008235""(metalloexopeptidase activity)|go:""GO:0016795""(phosphoric triester hydrolase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0102009""(proline dipeptidase activity)|interpro:IPR052433|refseq:YP_002348644.1|panther:PTHR43226(orthology-group)"	"ensembl:ENSG00000162434.14(gene)|ensembl:ENST00000342505.5(transcript)|ensembl:ENST00000671929.2(transcript)|ensembl:ENST00000671954.2(transcript)|ensembl:ENST00000672179.2(transcript)|ensembl:ENST00000672247.2(transcript)|ensembl:ENST00000672434.2(transcript)|ensembl:ENST00000672751.2(transcript)|ensembl:ENST00000699262.1(transcript)|ensembl:ENST00000699312.1(transcript)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005131""(growth hormone receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038196""(type III interferon-mediated signaling pathway)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046872""(metal ion binding)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|interpro:IPR051286|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|rcsb pdb:8EXJ|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9732724|reactome:R-HSA-9833109|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|refseq:NP_001308785.1|refseq:NP_002218.2|dip:DIP-133N|panther:PTHR45807(orthology-group)|efo:""Orphanet:574957""|efo:""Orphanet:667662""|ensembl:ENSP00000343204.4|ensembl:ENSP00000500485.1|ensembl:ENSP00000500841.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:y6CN8bCDiK4wzsPoNdgHT93LVx0632	rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606	intact-crc:CD62260D017BB84A|rigid:zSzaXa1+UrL7Jf0lvAlTm1jB0zk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P41229	uniprotkb:A0A2U2GUN8	intact:EBI-1246541|uniprotkb:B4E3I2|uniprotkb:F5H3T1|uniprotkb:Q5JUX3|uniprotkb:Q5JUX4|uniprotkb:Q5JUX5|uniprotkb:Q7Z5S5|uniprotkb:B0QZ44|ensembl:ENSP00000364550.4|intact:EBI-28983825	intact:EBI-2844713|uniprotkb:Q74T17|uniprotkb:Q0WDV8|uniprotkb:Q7CJ97|uniprotkb:A0A3N4AZU4|uniprotkb:A0A384KTX0	"psi-mi:kdm5c_human(display_long)|uniprotkb:KDM5C(gene name)|psi-mi:KDM5C(display_short)|uniprotkb:DXS1272E(gene name synonym)|uniprotkb:SMCX(gene name synonym)|uniprotkb:XE169(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1C(gene name synonym)|uniprotkb:Protein SmcX(gene name synonym)|uniprotkb:Protein Xe169(gene name synonym)|uniprotkb:JARID1C(gene name synonym)|uniprotkb:Histone demethylase JARID1C(gene name synonym)|uniprotkb:""[histone H3]-trimethyl-L-lysine(4) demethylase 5C""(gene name synonym)"	psi-mi:a0a2u2gun8_yerpe(display_long)|uniprotkb:YPO2569(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866394|imex:IM-13779-7212	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000126012.14(gene)|ensembl:ENST00000375401.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009636""(response to toxic substance)|go:""GO:0032452""(histone demethylase activity)|go:""GO:0032453""(histone H3K4 demethylase activity)|go:""GO:0034647""(histone H3K4me/H3K4me2/H3K4me3 demethylase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048511""(rhythmic process)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|interpro:IPR048615|mint:P41229|rcsb pdb:2JRZ|rcsb pdb:5FWJ|reactome:R-HSA-3214842|refseq:NP_001140174.1|refseq:NP_001269551.1|refseq:NP_004178.2|refseq:XP_005262092.1|refseq:XP_011529128.1|dip:DIP-39663N|efo:""Orphanet:85279""|panther:PTHR10694(orthology-group)|ensembl:ENST00000375379.7|ensembl:ENSP00000364528.3|ensembl:ENST00000375383.7|ensembl:ENSP00000364532.3|ensembl:ENSP00000364550.4|ensembl:ENST00000404049.7|ensembl:ENSP00000385394.3|ensembl:ENST00000452825.7|ensembl:ENSP00000445176.1"	"rcsb pdb:3OXP|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_002210291.1|go:""GO:0005737""(cytoplasm)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|refseq:YP_002347530.1|interpro:IPR051351"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/19	rogid:sBtK/VaMcyTMcinoqnOqwBdl7TM9606	rogid:WexLHH5KTrnggqyPy38AGIRlsdI632	intact-crc:8157876123728636|rigid:UtdwovWdTA57080G6wZeBai6DIQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q74PW2	uniprotkb:Q96ST2	intact:EBI-2858445|uniprotkb:Q8CZM9	intact:EBI-2515615|uniprotkb:Q2TB65|uniprotkb:Q9NV97|uniprotkb:Q96MI7|uniprotkb:Q9NWH8|uniprotkb:Q6P157|uniprotkb:Q8N3E8|ensembl:ENSP00000295321.4	psi-mi:lsrb_yerpe(display_long)|uniprotkb:lsrB(gene name)|psi-mi:lsrB(display_short)|uniprotkb:YPO0409(locus name)|uniprotkb:y3772(locus name)|uniprotkb:YP_3772(locus name)	psi-mi:iws1_human(display_long)|uniprotkb:IWS1(gene name)|psi-mi:IWS1(display_short)|uniprotkb:IWS1L(gene name synonym)|uniprotkb:IWS1-like protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866401|imex:IM-13779-7213	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028082|rcsb pdb:3T95|interpro:IPR025997|interpro:IPR050555|interpro:IPR030159|refseq:WP_002209189.1|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|refseq:YP_002345486.1"	"refseq:NP_060439.2|ensembl:ENSG00000163166.15(gene)|ensembl:ENST00000295321.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0010793""(regulation of mRNA export from nucleus)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0050684""(regulation of mRNA processing)|go:""GO:0140673""(transcription elongation-coupled chromatin remodeling)|interpro:IPR017923|interpro:IPR035441|interpro:IPR051037|mint:Q96ST2|rcsb pdb:6EMR|rcsb pdb:6ZV1|rcsb pdb:6ZV4|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|panther:PTHR46010(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HwGPUMANnHZjBVvIO9NkzMLorcQ632	rogid:G7KjbkwlfWdg2VufnJfRBiS/yUs9606	intact-crc:C3FC07E27127841E|rigid:WRNPPYun1sQYUv9TJrAGhMdOh2g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NQC1	uniprotkb:A0A2U2GZL1	intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q6IE80|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q96GQ6|ensembl:ENSP00000378451.1	intact:EBI-2854458|uniprotkb:Q74PS2|uniprotkb:Q0WB90|uniprotkb:A0A5P8YJZ1|uniprotkb:Q7CL96|uniprotkb:A0A384KMD8	psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym)	psi-mi:a0a2u2gzl1_yerpe(display_long)|uniprotkb:pog(gene name)|psi-mi:pog(display_short)|uniprotkb:ssp(gene name synonym)|uniprotkb:sspA(gene name synonym)|uniprotkb:YPO3561(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866387|imex:IM-13779-7211	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143.22(gene)|ensembl:ENST00000395003.5(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000278""(regulation of DNA biosynthetic process)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|interpro:IPR050701|mint:Q9NQC1|reactome:R-HSA-3214847|panther:PTHR13793(orthology-group)"	interpro:IPR050983|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|rcsb pdb:1YY7|refseq:WP_002210135.1|interpro:IPR034341|interpro:IPR040079|interpro:IPR036249|interpro:IPR036282|refseq:YP_002348448.1|interpro:IPR034342	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606	rogid:9smmAt4ZQb55TC9gx1z1tyl4bTI632	intact-crc:F6E624EE92FD4637|rigid:5EeC0YSxMrTyuy+g2TX1FeuUOeY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0P9	uniprotkb:Q9NQC1	intact:EBI-2856577|uniprotkb:Q74UF2	intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q6IE80|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q96GQ6|ensembl:ENSP00000378451.1	psi-mi:q8d0p9_yerpe(display_long)|uniprotkb:aer(gene name)|psi-mi:aer(display_short)|uniprotkb:YP_1774(locus name)|uniprotkb:y1805(locus name)	psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866380|imex:IM-13779-7210	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR051310|interpro:IPR013655(PAS fold-3)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR035965"	"refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143.22(gene)|ensembl:ENST00000395003.5(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000278""(regulation of DNA biosynthetic process)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|interpro:IPR050701|mint:Q9NQC1|reactome:R-HSA-3214847|panther:PTHR13793(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UQ1nmynYyPCB+ni3UxBTbLxoRNg632	rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606	intact-crc:060476F4E0EF536B|rigid:cvFIo5j2sCHHkMPChwIBDYh4peM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5KZU3	uniprotkb:P26440	intact:EBI-2850940	intact:EBI-2866408|uniprotkb:J3KR54|uniprotkb:Q53XZ9|uniprotkb:Q96AF6|uniprotkb:B2RCV5|uniprotkb:B3KVI7|ensembl:ENSP00000499074.1	psi-mi:a0a3g5kzu3_yerpe(display_long)|uniprotkb:y0245(locus name)|uniprotkb:ssuA(gene name)|psi-mi:ssuA(display_short)	psi-mi:ivd_human(display_long)|uniprotkb:IVD(gene name)|psi-mi:IVD(display_short)|uniprotkb:Butyryl-CoA dehydrogenase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866414|imex:IM-13779-7209	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR010067(ABC transporter, substrate-binding protein, aliphatic sulphonates)|interpro:IPR015168(NMT1/THI5 like)|uniprotkb:A0A6B3T643(uniprot-removed-ac)|go:""GO:0016020""(membrane)|go:""GO:0042597""(periplasmic space)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|refseq:WP_002220949.1"	"ensembl:ENSG00000128928.10(gene)|ensembl:ENST00000651168.1(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006552""(L-leucine catabolic process)|go:""GO:0008470""(3-methylbutanoyl-CoA dehydrogenase activity)|go:""GO:0009083""(branched-chain amino acid catabolic process)|go:""GO:0033539""(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:""GO:0042802""(identical protein binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034183|interpro:IPR036250|interpro:IPR037069|interpro:IPR046373|mint:P26440|rcsb pdb:1IVH|rcsb pdb:8SGR|reactome:R-HSA-70895|reactome:R-HSA-9914355|refseq:NP_001152980.1|refseq:NP_002216.2|efo:""Orphanet:33""|panther:PTHR43884(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kuMqjHfkYUIBJ4hy+1j+bwqjjo4632	rogid:GewB1Yyc2EEVepN5e1H068xpjI09606	intact-crc:3A0F0E4DA73EA1EB|rigid:d5POekrFbidULNxN+uM2w3fJ6b8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKW8	uniprotkb:Q14573	intact:EBI-2866424	intact:EBI-351055|uniprotkb:Q14649|uniprotkb:Q5TAQ2|intact:EBI-28978202|ensembl:ENSP00000363435.4|ensembl:ENSP00000475177.1	psi-mi:q8ckw8_yerpe(display_long)|uniprotkb:y2697(locus name)	psi-mi:itpr3_human(display_long)|uniprotkb:ITPR3(gene name)|psi-mi:ITPR3(display_short)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866421|imex:IM-13779-7214	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023346|interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR050570|go:""GO:0005886""(plasma membrane)"	"refseq:NP_002215.2|ensembl:ENSG00000096433.11(gene)|ensembl:ENST00000374316.9(transcript)|ensembl:ENST00000605930.3(transcript)|go:""GO:0000822""(inositol hexakisphosphate binding)|go:""GO:0005220""(inositol 1,4,5-trisphosphate-gated calcium channel activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007613""(memory)|go:""GO:0015278""(intracellularly gated calcium channel activity)|go:""GO:0016020""(membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0030168""(platelet activation)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043235""(receptor complex)|go:""GO:0043533""(inositol 1,3,4,5 tetrakisphosphate binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0050909""(sensory perception of taste)|go:""GO:0050913""(sensory perception of bitter taste)|go:""GO:0050916""(sensory perception of sweet taste)|go:""GO:0050917""(sensory perception of umami taste)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0051592""(response to calcium ion)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR015925(Ryanodine receptor-related)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14573|rcsb pdb:6DQJ|rcsb pdb:6DQN|rcsb pdb:6DQS|rcsb pdb:6DQV|rcsb pdb:6DQZ|rcsb pdb:6DR0|rcsb pdb:6DR2|rcsb pdb:6DRA|rcsb pdb:6DRC|rcsb pdb:6UQK|rcsb pdb:7T3P|rcsb pdb:7T3Q|rcsb pdb:7T3R|rcsb pdb:7T3T|rcsb pdb:7T3U|rcsb pdb:8TK8|rcsb pdb:8TKD|rcsb pdb:8TKE|rcsb pdb:8TKF|rcsb pdb:8TKG|rcsb pdb:8TKH|rcsb pdb:8TKI|rcsb pdb:8TL9|rcsb pdb:8TLA|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-9717207|reactome:R-HSA-983695|panther:PTHR13715(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CvaJpk+6XrtKQM2J/bdU6BsUtcI632	rogid:O+1OC4E0IrAOt+D672eXnhWHy3I9606	intact-crc:7DD57700F23FD582|rigid:rkrd71pghUKTm3KAKclXv3KS9yU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q9Y287	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-2866431|uniprotkb:Q5W0A3|uniprotkb:Q96B24|uniprotkb:Q9NYH1|ensembl:ENSP00000497221.1	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:itm2b_human(display_long)|uniprotkb:ITM2B(gene name)|psi-mi:ITM2B(display_short)|uniprotkb:BRI(gene name synonym)|uniprotkb:BRI2(gene name synonym)|uniprotkb:Protein E25B(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)|uniprotkb:Immature BRI2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866450|imex:IM-13779-7215	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"ensembl:ENSG00000136156.15(gene)|ensembl:ENST00000647800.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0007399""(nervous system development)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030660""(Golgi-associated vesicle membrane)|go:""GO:0031090""(organelle membrane)|go:""GO:0042985""(negative regulation of amyloid precursor protein biosynthetic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q9Y287|rcsb pdb:8RNU|reactome:R-HSA-977225|refseq:NP_068839.1|efo:""Orphanet:97345""|efo:""Orphanet:97346""|efo:""Orphanet:397758""|panther:PTHR10962(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:9mHhC4Z61CsmOsTh/1K9oj2NezA9606	intact-crc:F4569DC012E5C8E9|rigid:DFIElNdJ7gK+jwZW2eaj4FdPYpc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y287	uniprotkb:Q8CZW4	intact:EBI-2866431|uniprotkb:Q5W0A3|uniprotkb:Q96B24|uniprotkb:Q9NYH1|ensembl:ENSP00000497221.1	intact:EBI-2851384|uniprotkb:Q74QA0	psi-mi:itm2b_human(display_long)|uniprotkb:ITM2B(gene name)|psi-mi:ITM2B(display_short)|uniprotkb:BRI(gene name synonym)|uniprotkb:BRI2(gene name synonym)|uniprotkb:Protein E25B(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)|uniprotkb:Immature BRI2(gene name synonym)	psi-mi:q8czw4_yerpe(display_long)|uniprotkb:y3277(locus name)|uniprotkb:fldB(gene name)|psi-mi:fldB(display_short)|uniprotkb:YP_3589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866443|imex:IM-13779-7216	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000136156.15(gene)|ensembl:ENST00000647800.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0007399""(nervous system development)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030660""(Golgi-associated vesicle membrane)|go:""GO:0031090""(organelle membrane)|go:""GO:0042985""(negative regulation of amyloid precursor protein biosynthetic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q9Y287|rcsb pdb:8RNU|reactome:R-HSA-977225|refseq:NP_068839.1|efo:""Orphanet:97345""|efo:""Orphanet:97346""|efo:""Orphanet:397758""|panther:PTHR10962(orthology-group)"	"interpro:IPR029039|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001226(Flavodoxin, conserved site)|interpro:IPR010086(Flavodoxin, long chain)|go:""GO:0009055""(electron transfer activity)|go:""GO:0010181""(FMN binding)|interpro:IPR050619"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9mHhC4Z61CsmOsTh/1K9oj2NezA9606	rogid:FZlCLDczSf2Gjm4UsIPSSoGJH6E632	intact-crc:FE0F1BDBCC761C96|rigid:RiZ3IqO3ajVz0sWORXx2mw42668	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0S2	uniprotkb:Q9Y287	intact:EBI-2860250	intact:EBI-2866431|uniprotkb:Q5W0A3|uniprotkb:Q96B24|uniprotkb:Q9NYH1|ensembl:ENSP00000497221.1	psi-mi:q8d0s2_yerpe(display_long)|uniprotkb:y1672(locus name)	psi-mi:itm2b_human(display_long)|uniprotkb:ITM2B(gene name)|psi-mi:ITM2B(display_short)|uniprotkb:BRI(gene name synonym)|uniprotkb:BRI2(gene name synonym)|uniprotkb:Protein E25B(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)|uniprotkb:Immature BRI2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866436|imex:IM-13779-7217	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR050903|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|interpro:IPR035965|interpro:IPR013655(PAS fold-3)"	"ensembl:ENSG00000136156.15(gene)|ensembl:ENST00000647800.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0007399""(nervous system development)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030660""(Golgi-associated vesicle membrane)|go:""GO:0031090""(organelle membrane)|go:""GO:0042985""(negative regulation of amyloid precursor protein biosynthetic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q9Y287|rcsb pdb:8RNU|reactome:R-HSA-977225|refseq:NP_068839.1|efo:""Orphanet:97345""|efo:""Orphanet:97346""|efo:""Orphanet:397758""|panther:PTHR10962(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ijy2z//5zbVT/OTgKSlRqBBFln8632	rogid:9mHhC4Z61CsmOsTh/1K9oj2NezA9606	intact-crc:2BF4238CCDBD791C|rigid:6D723SXyv2ieHbCvU5FaeNQyDwg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBN2	uniprotkb:Q9Y287	intact:EBI-2866457|uniprotkb:Q0WBS0	intact:EBI-2866431|uniprotkb:Q5W0A3|uniprotkb:Q96B24|uniprotkb:Q9NYH1|ensembl:ENSP00000497221.1	psi-mi:eno_yerpe(display_long)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:YPO3376(locus name)|uniprotkb:y0814(locus name)|uniprotkb:YP_0310(locus name)	psi-mi:itm2b_human(display_long)|uniprotkb:ITM2B(gene name)|psi-mi:ITM2B(display_short)|uniprotkb:BRI(gene name synonym)|uniprotkb:BRI2(gene name synonym)|uniprotkb:Protein E25B(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)|uniprotkb:Immature BRI2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866462|imex:IM-13779-7218	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000941(Enolase)|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|refseq:WP_002209377.1|go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006096""(glycolytic process)|go:""GO:0009986""(cell surface)|refseq:YP_002348268.1|panther:PTHR11902(orthology-group)"	"ensembl:ENSG00000136156.15(gene)|ensembl:ENST00000647800.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0007399""(nervous system development)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030660""(Golgi-associated vesicle membrane)|go:""GO:0031090""(organelle membrane)|go:""GO:0042985""(negative regulation of amyloid precursor protein biosynthetic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q9Y287|rcsb pdb:8RNU|reactome:R-HSA-977225|refseq:NP_068839.1|efo:""Orphanet:97345""|efo:""Orphanet:97346""|efo:""Orphanet:397758""|panther:PTHR10962(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Wv24HGwqOUCul2bvS0kXRmQ7uR0632	rogid:9mHhC4Z61CsmOsTh/1K9oj2NezA9606	intact-crc:B5816232CDBB6C5D|rigid:Q9tCx8GuxgPEubOUXhloA7pfuk8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16144	uniprotkb:Q56989	intact:EBI-948678|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97|ensembl:ENSP00000200181.3	intact:EBI-2860949|uniprotkb:Q0WK23	psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short)	psi-mi:hmur_yerpe(display_long)|uniprotkb:hmuR(gene name)|psi-mi:hmuR(display_short)|uniprotkb:YPO0283(locus name)|uniprotkb:y0543(locus name)|uniprotkb:YP_0438(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866490|imex:IM-13779-7220	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-40182N|efo:""Orphanet:1114""|efo:""Orphanet:158684""|efo:""Orphanet:251393""|efo:""Orphanet:79402""|efo:""Orphanet:79403""|ensembl:ENSG00000132470.14(gene)|ensembl:ENST00000200181.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006914""(autophagy)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009611""(response to wounding)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030054""(cell junction)|go:""GO:0030056""(hemidesmosome)|go:""GO:0031252""(cell leading edge)|go:""GO:0031581""(hemidesmosome assembly)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032290""(peripheral nervous system myelin formation)|go:""GO:0035878""(nail development)|go:""GO:0043235""(receptor complex)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0046847""(filopodium assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048870""(cell motility)|go:""GO:0061450""(trophoblast cell migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|reactome:R-HSA-9725554|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1|panther:PTHR10082(orthology-group)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR011276(TonB-dependent haem/haemoglobin receptor)|interpro:IPR010949(TonB-dependent haemoglobin/transferrin/lactoferrin receptor)|refseq:WP_002209062.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015232""(heme transmembrane transporter activity)|go:""GO:0015344""(siderophore uptake transmembrane transporter activity)|go:""GO:0044718""(siderophore transmembrane transport)|go:""GO:0071281""(cellular response to iron ion)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002345365.1|panther:PTHR30069(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606	rogid:+01B95YakdqYxalnNbktgrTkIok632	intact-crc:9A9DF6E3C4962A53|rigid:3GUVsM+IoJS4ZndBKXV2vHyUljc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16144	uniprotkb:A0A2S9PFM0	intact:EBI-948678|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97|ensembl:ENSP00000200181.3	intact:EBI-2846871|uniprotkb:Q74QH1|uniprotkb:A0A0H2W7H4|uniprotkb:Q7CGR9|uniprotkb:A0A384LFS9	psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short)	psi-mi:a0a2s9pfm0_yerpe(display_long)|uniprotkb:YPO0938(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866476|imex:IM-13779-7222	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-40182N|efo:""Orphanet:1114""|efo:""Orphanet:158684""|efo:""Orphanet:251393""|efo:""Orphanet:79402""|efo:""Orphanet:79403""|ensembl:ENSG00000132470.14(gene)|ensembl:ENST00000200181.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006914""(autophagy)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009611""(response to wounding)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030054""(cell junction)|go:""GO:0030056""(hemidesmosome)|go:""GO:0031252""(cell leading edge)|go:""GO:0031581""(hemidesmosome assembly)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032290""(peripheral nervous system myelin formation)|go:""GO:0035878""(nail development)|go:""GO:0043235""(receptor complex)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0046847""(filopodium assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048870""(cell motility)|go:""GO:0061450""(trophoblast cell migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|reactome:R-HSA-9725554|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1|panther:PTHR10082(orthology-group)"	"interpro:IPR017755(N-carbamoylputrescine amidase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:WP_002209979.1|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0050126""(N-carbamoylputrescine amidase activity)|interpro:IPR036526|refseq:YP_002345985.1|interpro:IPR050345"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606	rogid:VEt5ZICBEzJqD2dQaZCgWKgplSI632	intact-crc:3344E7CAAB31E691|rigid:Lfelhxr5hJHd9P0Zy5dSgCQ4z+U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YMM0	uniprotkb:P16144	intact:EBI-2844994|uniprotkb:Q74PA7|uniprotkb:Q7CFN1|uniprotkb:A0A0H2W8G4	intact:EBI-948678|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97|ensembl:ENSP00000200181.3	psi-mi:a0a5p8ymm0_yerpe(display_long)|uniprotkb:YPO4111(locus name)	psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866483|imex:IM-13779-7221	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR018313|go:""GO:0005576""(extracellular region)|go:""GO:0006865""(amino acid transport)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|refseq:WP_002215568.1|refseq:YP_002348962.1|interpro:IPR051455|panther:PTHR30085(orthology-group)"	"dip:DIP-40182N|efo:""Orphanet:1114""|efo:""Orphanet:158684""|efo:""Orphanet:251393""|efo:""Orphanet:79402""|efo:""Orphanet:79403""|ensembl:ENSG00000132470.14(gene)|ensembl:ENST00000200181.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006914""(autophagy)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009611""(response to wounding)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030054""(cell junction)|go:""GO:0030056""(hemidesmosome)|go:""GO:0031252""(cell leading edge)|go:""GO:0031581""(hemidesmosome assembly)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032290""(peripheral nervous system myelin formation)|go:""GO:0035878""(nail development)|go:""GO:0043235""(receptor complex)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0046847""(filopodium assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048870""(cell motility)|go:""GO:0061450""(trophoblast cell migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|reactome:R-HSA-9725554|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1|panther:PTHR10082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:/TF3wEkKv/JvJMW7WimwR6S7ryU632	rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606	intact-crc:F2E078A02E7FE4E0|rigid:+cyPFtXZTAM6hvEbpFqiKocunbI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P26010	uniprotkb:Q7CFY4	intact:EBI-702932|uniprotkb:Q9UCP7|uniprotkb:Q9UCS7|ensembl:ENSP00000267082.4|ensembl:ENSP00000408741.3	intact:EBI-2839980|uniprotkb:Q0WA73	psi-mi:itb7_human(display_long)|uniprotkb:Gut homing receptor beta subunit(gene name synonym)|uniprotkb:ITGB7(gene name)|psi-mi:ITGB7(display_short)	psi-mi:q7cfy4_yerpe(display_long)|uniprotkb:YPO3944(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866469|imex:IM-13779-7219	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000880.1|refseq:XP_005268908.1|refseq:XP_005268909.1|ensembl:ENSG00000139626.16(gene)|ensembl:ENST00000267082.10(transcript)|ensembl:ENST00000422257.7(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0002387""(immune response in gut-associated lymphoid tissue)|go:""GO:0003366""(cell-matrix adhesion involved in ameboidal cell migration)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034669""(integrin alpha4-beta7 complex)|go:""GO:0043113""(receptor clustering)|go:""GO:0043235""(receptor complex)|go:""GO:0046872""(metal ion binding)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050900""(leukocyte migration)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072678""(T cell migration)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|mint:P26010|rcsb pdb:2BRQ|rcsb pdb:3V4P|rcsb pdb:3V4V|rcsb pdb:8ZJF|reactome:R-HSA-198933|reactome:R-HSA-216083|dip:DIP-34970N|panther:PTHR10082(orthology-group)"	"interpro:IPR003344(Bacterial Ig-like, group 1)|interpro:IPR024519|interpro:IPR003535(Intimin bacterial adhesion mediator protein)|interpro:IPR008964(Invasin/intimin cell-adhesion)|interpro:IPR018392|refseq:YP_002348815.1|interpro:IPR016186(C-type lectin-like)|interpro:IPR048658|go:""GO:0007155""(cell adhesion)|go:""GO:0009279""(cell outer membrane)|interpro:IPR038177|refseq:WP_002228169.1|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036779|interpro:IPR051715|panther:PTHR39576(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mRv+7ZBLDgWEfr8pRV70UUUedgM9606	rogid:HyjrywO1mfKosC2W72qtvq9hL6w632	intact-crc:3548C26302F05795|rigid:SkWXy4nEg2XYkMq1oMI74edR/DE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GWZ3	uniprotkb:P05107	intact:EBI-2854963|uniprotkb:Q74RC3|uniprotkb:A0A0H2W745|uniprotkb:A0A3N4BB56|uniprotkb:Q7CL06|uniprotkb:A0A384LLZ0	intact:EBI-300173|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1|ensembl:ENSP00000347279.4|ensembl:ENSP00000380948.2|ensembl:ENSP00000380950.1|ensembl:ENSP00000380955.1|ensembl:ENSP00000498780.1	psi-mi:a0a2u2gwz3_yerpe(display_long)|uniprotkb:YPO3907(locus name)	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866504|imex:IM-13779-7227	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050107|interpro:IPR017871|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_002212023.1|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_002348782.1|interpro:IPR049716"	"efo:""Orphanet:99842""|ensembl:ENSG00000160255.19(gene)|ensembl:ENST00000355153.8(transcript)|ensembl:ENST00000397850.6(transcript)|ensembl:ENST00000397852.5(transcript)|ensembl:ENST00000397857.5(transcript)|ensembl:ENST00000652462.1(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0002523""(leukocyte migration involved in inflammatory response)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008305""(integrin complex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030369""(ICAM-3 receptor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031623""(receptor internalization)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034687""(integrin alphaL-beta2 complex)|go:""GO:0034688""(integrin alphaM-beta2 complex)|go:""GO:0034689""(integrin alphaX-beta2 complex)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0043113""(receptor clustering)|go:""GO:0043235""(receptor complex)|go:""GO:0043315""(positive regulation of neutrophil degranulation)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045123""(cellular extravasation)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045963""(negative regulation of dopamine metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1990266""(neutrophil migration)|go:""GO:2000363""(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|mint:P05107|rcsb pdb:1L3Y|rcsb pdb:1YUK|rcsb pdb:2JF1|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|rcsb pdb:4NEH|rcsb pdb:4NEN|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|rcsb pdb:7P2D|rcsb pdb:7USL|rcsb pdb:7USM|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|panther:PTHR10082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/01	rogid:kVgegxZzZ6FEjnxd5IUfBBaoYEU632	rogid:Q/zG7M9MczNRx1TBKx4rXH+87iY9606	intact-crc:66259D03A370EEC9|rigid:q/cUa+ZbaGKZmYJVguRExkqKDUU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A7D9NLK2	uniprotkb:Q9BUE6	intact:EBI-2842776	intact:EBI-2866528|uniprotkb:B3KP34|uniprotkb:Q8ND75|uniprotkb:Q9BZR2|uniprotkb:B4DJI5|ensembl:ENSP00000365159.4	psi-mi:a0a7d9nlk2_yerpe(display_long)|uniprotkb:ORF99(gene name)|psi-mi:ORF99(display_short)|uniprotkb:Y1060(locus name)	psi-mi:isca1_human(display_long)|uniprotkb:ISCA1(gene name)|psi-mi:ISCA1(display_short)|uniprotkb:HBLD2(gene name synonym)|uniprotkb:HESB-like domain-containing protein 2(gene name synonym)|uniprotkb:Iron-sulfur assembly protein IscA(gene name synonym)|uniprotkb:GK004(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866525|imex:IM-13779-7224	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002224265.1|refseq:YP_093964.1|uniprotkb:A0A5K1VD91(uniprot-removed-ac)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"ensembl:ENSG00000135070.15(gene)|ensembl:ENST00000375991.9(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0016226""(iron-sulfur cluster assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0097428""(obsolete protein maturation by iron-sulfur cluster transfer)|go:""GO:0120510""(mitochondrial [4Fe-4S] assembly complex)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|interpro:IPR050322|mint:Q9BUE6|reactome:R-HSA-1362409|reactome:R-HSA-9854311|refseq:NP_112202.2|efo:""Orphanet:569274""|panther:PTHR10072(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:drpdmgWm7Xi1tzOHiVuDwatPqrI632	rogid:ydND+wkG6OPkv24x5GWefAIa6309606	intact-crc:04E4FBF5B255565A|rigid:YMmMlzrcPuvDgZ8J01Lva41TYRI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P05556	uniprotkb:A0A3N4B418	intact:EBI-703066|intact:EBI-4289597|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5|ensembl:ENSP00000303351.3|ensembl:ENSP00000379350.2|ensembl:ENSP00000398029.2|ensembl:ENSP00000404546.3|ensembl:ENSP00000502882.1|ensembl:ENSP00000503546.1|ensembl:ENSP00000503916.1|ensembl:ENSP00000504205.1|ensembl:ENSP00000504444.1	intact:EBI-2840046|uniprotkb:Q0WFD2|uniprotkb:Q74U73|uniprotkb:Q7CIA4|uniprotkb:A0A380PD11	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:a0a3n4b418_yerpe(display_long)|uniprotkb:YPO2020(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866511|imex:IM-13779-7226	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|ensembl:ENSG00000150093.20(gene)|ensembl:ENST00000302278.8(transcript)|ensembl:ENST00000396033.6(transcript)|ensembl:ENST00000417122.7(transcript)|ensembl:ENST00000437302.6(transcript)|ensembl:ENST00000677999.1(transcript)|ensembl:ENST00000678701.1(transcript)|ensembl:ENST00000678943.1(transcript)|ensembl:ENST00000678952.1(transcript)|dip:DIP-312N|ensembl:ENST00000678989.1(transcript)|go:""GO:0000082""(G1/S transition of mitotic cell cycle)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001726""(ruffle)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002020""(protease binding)|go:""GO:0002042""(cell migration involved in sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006909""(phagocytosis)|go:""GO:0006968""(cellular defense response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007161""(calcium-independent cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0007517""(muscle organ development)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008305""(integrin complex)|go:""GO:0008354""(germ cell migration)|go:""GO:0008542""(visual learning)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010710""(regulation of collagen catabolic process)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0014704""(intercalated disc)|go:""GO:0014850""(response to muscle activity)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0023035""(CD40 signaling pathway)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030175""(filopodium)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030198""(extracellular matrix organization)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031623""(receptor internalization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032587""(ruffle membrane)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0033631""(cell-cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034665""(integrin alpha1-beta1 complex)|go:""GO:0034666""(integrin alpha2-beta1 complex)|go:""GO:0034667""(integrin alpha3-beta1 complex)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0034674""(integrin alpha5-beta1 complex)|go:""GO:0034675""(integrin alpha6-beta1 complex)|go:""GO:0034677""(integrin alpha7-beta1 complex)|go:""GO:0034678""(integrin alpha8-beta1 complex)|go:""GO:0034679""(integrin alpha9-beta1 complex)|go:""GO:0034680""(integrin alpha10-beta1 complex)|go:""GO:0034681""(integrin alpha11-beta1 complex)|go:""GO:0034682""(integrin alphav-beta1 complex)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0035748""(myelin sheath abaxonal region)|go:""GO:0042383""(sarcolemma)|go:""GO:0042470""(melanosome)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043197""(dendritic spine)|go:""GO:0043235""(receptor complex)|go:""GO:0043236""(laminin binding)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045121""(membrane raft)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045743""(positive regulation of fibroblast growth factor receptor signaling pathway)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045906""(negative regulation of vasoconstriction)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048626""(myoblast fate specification)|go:""GO:0048675""(axon extension)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050901""(leukocyte tethering or rolling)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051951""(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0055037""(recycling endosome)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060912""(cardiac cell fate specification)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071711""(basement membrane organization)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097386""(glial cell projection)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0150003""(regulation of spontaneous synaptic transmission)|go:""GO:0150053""(cerebellar climbing fiber to Purkinje cell synapse)|go:""GO:0150103""(reactive gliosis)|go:""GO:1900748""(positive regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901979""(regulation of inward rectifier potassium channel activity)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905806""(regulation of synapse pruning)|go:""GO:1990782""(protein tyrosine kinase binding)|go:""GO:2000811""(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|rcsb pdb:7CEB|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEC|rcsb pdb:7NWL|rcsb pdb:7NXD|rcsb pdb:8RPQ|rcsb pdb:9CKV|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9634597|reactome:R-HSA-9679191|reactome:R-HSA-9725554|reactome:R-HSA-9830674|reactome:R-HSA-9860927|panther:PTHR10082(orthology-group)"	refseq:YP_002347006.1|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR032698|refseq:WP_002211233.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rogid:wzxT1bjS3dgwqWVrMmCge2eTVT0632	intact-crc:87938BFF2D6A76EF|rigid:TEpHJDUknQej8TQqa5kOGnQlYUs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P56199	uniprotkb:A0A3G5L9M4	intact:EBI-2554465|uniprotkb:B2RNU0|ensembl:ENSP00000282588.5	intact:EBI-2844699	psi-mi:ita1_human(display_long)|uniprotkb:ITGA1(gene name)|psi-mi:ITGA1(display_short)|uniprotkb:Laminin and collagen receptor(gene name synonym)|uniprotkb:VLA-1(gene name synonym)|uniprotkb:CD49 antigen-like family member A(gene name synonym)	psi-mi:a0a3g5l9m4_yerpe(display_long)|uniprotkb:yceD_2(gene name synonym)|uniprotkb:NCTC5923_03599(orf name)|uniprotkb:y0556(locus name)|uniprotkb:terA(gene name)|psi-mi:terA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866518|imex:IM-13779-7225	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_852478.1|dip:DIP-206N|ensembl:ENSG00000213949.10(gene)|ensembl:ENST00000282588.7(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008305""(integrin complex)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019211""(phosphatase activator activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034665""(integrin alpha1-beta1 complex)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042311""(vasodilation)|go:""GO:0043204""(perikaryon)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045123""(cellular extravasation)|go:""GO:0045178""(basal part of cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098639""(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|interpro:IPR048285|interpro:IPR048286|mint:P56199|rcsb pdb:1PT6|rcsb pdb:1QC5|rcsb pdb:1QCY|rcsb pdb:2L8S|rcsb pdb:2M32|rcsb pdb:4A0Q|rcsb pdb:5HGJ|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-416700|reactome:R-HSA-445355|reactome:R-HSA-447041|reactome:R-HSA-75892|panther:PTHR23220(orthology-group)"	"go:""GO:0046690""(response to tellurium ion)|uniprotkb:A0A2U2H1B9(uniprot-removed-ac)|interpro:IPR003325(Bacterial stress protein)|interpro:IPR017115(Tellurite resistance, TerA)|refseq:WP_002209075.1|interpro:IPR051324"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/08	rogid:rI8GnpuQlkN7TAnJ2eLpECEZOxs9606	rogid:pmp0dKUKap1cp8P701GLyujbyQ8632	intact-crc:74D04C3931DFF992|rigid:HlGCNJMjs1LeOEzOfA3hjAv71jk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKI8	uniprotkb:P05106	intact:EBI-2855532	intact:EBI-702847|uniprotkb:A0PJW2|uniprotkb:O15495|uniprotkb:Q12806|uniprotkb:Q13413|uniprotkb:Q14648|uniprotkb:Q16499|uniprotkb:D3DXJ8|ensembl:ENSP00000452786.2	psi-mi:q8cki8_yerpe(display_long)|uniprotkb:NCTC5923_02392(orf name)|uniprotkb:y3427(locus name)	psi-mi:itb3_human(display_long)|uniprotkb:Platelet membrane glycoprotein IIIa(gene name synonym)|uniprotkb:ITGB3(gene name)|psi-mi:ITGB3(display_short)|uniprotkb:GP3A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866497|imex:IM-13779-7223	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002213742.1	"efo:""Orphanet:140957""|efo:""Orphanet:849""|efo:""Orphanet:853""|ensembl:ENSG00000259207.10(gene)|ensembl:ENST00000559488.7(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0001968""(fibronectin binding)|go:""GO:0002020""(protease binding)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005161""(platelet-derived growth factor receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007044""(cell-substrate junction assembly)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|reactome:R-HSA-114608|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007566""(embryo implantation)|go:""GO:0007596""(blood coagulation)|go:""GO:0008305""(integrin complex)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010628""(positive regulation of gene expression)|reactome:R-HSA-1566948|go:""GO:0010745""(negative regulation of macrophage derived foam cell differentiation)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0014823""(response to activity)|go:""GO:0014909""(smooth muscle cell migration)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030168""(platelet activation)|go:""GO:0030949""(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031092""(platelet alpha granule membrane)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031527""(filopodium membrane)|go:""GO:0031528""(microvillus membrane)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0032147""(activation of protein kinase activity)|go:""GO:0032369""(negative regulation of lipid transport)|go:""GO:0032587""(ruffle membrane)|reactome:R-HSA-210990|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0033630""(positive regulation of cell adhesion mediated by integrin)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034683""(integrin alphav-beta3 complex)|go:""GO:0035295""(tube development)|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035866""(alphav-beta3 integrin-PKCalpha complex)|go:""GO:0035867""(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:""GO:0035868""(alphav-beta3 integrin-HMGB1 complex)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0038027""(apolipoprotein A-I-mediated signaling pathway)|go:""GO:0042060""(wound healing)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0043184""(vascular endothelial growth factor receptor 2 binding)|go:""GO:0043235""(receptor complex)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0045124""(regulation of bone resorption)|go:""GO:0045202""(synapse)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0046872""(metal ion binding)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050748""(negative regulation of lipoprotein metabolic process)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0050919""(negative chemotaxis)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051611""(regulation of serotonin uptake)|go:""GO:0060055""(angiogenesis involved in wound healing)|go:""GO:0070051""(fibrinogen binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070442""(integrin alphaIIb-beta3 complex)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071062""(alphav-beta3 integrin-vitronectin complex)|go:""GO:0071133""(alpha9-beta1 integrin-ADAM8 complex)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0072126""(positive regulation of glomerular mesangial cell proliferation)|go:""GO:0072378""(blood coagulation, fibrin clot formation)|go:""GO:0098690""(glycinergic synapse)|go:""GO:0098880""(maintenance of postsynaptic specialization structure)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099149""(regulation of postsynaptic neurotransmitter receptor internalization)|go:""GO:0150054""(regulation of postsynaptic neurotransmitter receptor diffusion trapping)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1900731""(positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:""GO:1901163""(regulation of trophoblast cell migration)|go:""GO:1903053""(regulation of extracellular matrix organization)|go:""GO:1905598""(negative regulation of low-density lipoprotein receptor activity)|go:""GO:1990314""(cellular response to insulin-like growth factor stimulus)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|go:""GO:2000406""(positive regulation of T cell migration)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05106|rcsb pdb:1JV2|rcsb pdb:1KUP|rcsb pdb:1KUZ|rcsb pdb:1L5G|rcsb pdb:1M1X|rcsb pdb:1M8O|rcsb pdb:1MIZ|rcsb pdb:1MK7|rcsb pdb:1MK9|rcsb pdb:1S4X|rcsb pdb:1TYE|rcsb pdb:1U8C|rcsb pdb:2K9J|rcsb pdb:2KNC|rcsb pdb:2KV9|rcsb pdb:2L1C|rcsb pdb:2L91|rcsb pdb:2LJD|rcsb pdb:2LJE|rcsb pdb:2LJF|rcsb pdb:2MTP|rcsb pdb:2N9Y|rcsb pdb:2Q6W|rcsb pdb:2RMZ|rcsb pdb:2RN0|rcsb pdb:2VC2|rcsb pdb:2VDK|rcsb pdb:2VDL|rcsb pdb:2VDM|rcsb pdb:2VDN|rcsb pdb:4Z7Q|rcsb pdb:2VDO|rcsb pdb:2VDP|rcsb pdb:2VDQ|rcsb pdb:2VDR|rcsb pdb:3FCS|rcsb pdb:3FCU|rcsb pdb:3IJE|rcsb pdb:3NID|rcsb pdb:3NIF|rcsb pdb:3NIG|rcsb pdb:3T3M|rcsb pdb:3T3P|rcsb pdb:3ZDX|rcsb pdb:3ZDY|rcsb pdb:3ZDZ|rcsb pdb:3ZE0|rcsb pdb:3ZE1|rcsb pdb:3ZE2|rcsb pdb:4CAK|rcsb pdb:4G1E|rcsb pdb:4G1M|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4O02|rcsb pdb:4Z7N|rcsb pdb:4Z7O|rcsb pdb:5HDB|rcsb pdb:6AVQ|rcsb pdb:6AVR|rcsb pdb:6AVU|rcsb pdb:6BXB|rcsb pdb:6BXF|rcsb pdb:6BXJ|rcsb pdb:6CKB|rcsb pdb:6MK0|rcsb pdb:6MSL|rcsb pdb:6MSU|rcsb pdb:6NAJ|rcsb pdb:6V4P|rcsb pdb:7KN0|rcsb pdb:7L8P|rcsb pdb:7LA4|rcsb pdb:7TCT|rcsb pdb:7TD8|rcsb pdb:7THO|rcsb pdb:7TMZ|rcsb pdb:7TPD|rcsb pdb:7U60|rcsb pdb:7U9F|rcsb pdb:7U9V|rcsb pdb:7UBR|rcsb pdb:7UCY|rcsb pdb:7UDG|rcsb pdb:7UDH|rcsb pdb:7UE0|rcsb pdb:7UFH|rcsb pdb:7UH8|rcsb pdb:7UJE|rcsb pdb:7UJK|rcsb pdb:7UK9|rcsb pdb:7UKO|rcsb pdb:7UKP|rcsb pdb:7UKT|rcsb pdb:8GCD|rcsb pdb:8GCE|rcsb pdb:8IJ5|rcsb pdb:8T2U|rcsb pdb:8T2V|rcsb pdb:9DEQ|rcsb pdb:9DER|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9860927|refseq:NP_000203.2|dip:DIP-304N|panther:PTHR10082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:kFpagl9Qd6b6ImFRX9++a7dnIjA632	rogid:EnuaoGdEG3SOqzwmTfH1OwqKuzs9606	intact-crc:3C37FE2A11A3FD8B|rigid:6xPm+QaWa2lLQWiFZ2WyOIrVz6s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NPI9	uniprotkb:A0A3G5L8E4	intact:EBI-2866539|ensembl:ENSP00000283936.1|ensembl:ENSP00000376438.1|ensembl:ENSP00000376439.1|ensembl:ENSP00000465967.1|ensembl:ENSP00000479817.1	intact:EBI-2855797	"psi-mi:kcj16_human(display_long)|uniprotkb:KCNJ16(gene name)|psi-mi:KCNJ16(display_short)|uniprotkb:""Inward rectifier K(+) channel Kir5.1""(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 16(gene name synonym)"	psi-mi:a0a3g5l8e4_yerpe(display_long)|uniprotkb:y1719(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866543|imex:IM-13779-7228	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001278551.1|refseq:NP_001278552.1|refseq:NP_001278553.1|refseq:NP_001278554.1|refseq:NP_733938.2|refseq:XP_011523083.1|refseq:NP_001257351.1|refseq:NP_061128.2|refseq:NP_733937.2|refseq:XP_016880102.1|ensembl:ENSG00000153822.15(gene)|ensembl:ENST00000283936.5(transcript)|ensembl:ENST00000392670.5(transcript)|ensembl:ENST00000392671.6(transcript)|ensembl:ENST00000589377.1(transcript)|ensembl:ENST00000615244.4(transcript)|go:""GO:0005242""(inward rectifier potassium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006813""(potassium ion transport)|go:""GO:0008076""(voltage-gated potassium channel complex)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0034765""(regulation of monoatomic ion transmembrane transport)|go:""GO:0071805""(potassium ion transmembrane transport)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR008061(Potassium channel, inwardly rectifying, Kir5)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:Q9NPI9|reactome:R-HSA-1296041|reactome:R-HSA-1296067|reactome:R-HSA-997272|panther:PTHR11767(orthology-group)"	uniprotkb:A0A2U2H0Q4(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cgDR01WvxCbADP2gurFz9jOWOrI9606	rogid:c6G8UaA9FOgYFgSiLNHnP1AxUhU632	intact-crc:4C7705094322EA03|rigid:1BvE8rCBmH/Cm/aKrYWm4eq3VL4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14654	uniprotkb:Q74R28	intact:EBI-2866553|uniprotkb:Q58EX3|uniprotkb:Q2M1H7|uniprotkb:B4DWI4|uniprotkb:E9PNK0|uniprotkb:Q8IW96|ensembl:ENSP00000345708.4	intact:EBI-2844649|uniprotkb:Q8D1I8	"psi-mi:kcj11_human(display_long)|uniprotkb:KCNJ11(gene name)|psi-mi:KCNJ11(display_short)|uniprotkb:IKATP(gene name synonym)|uniprotkb:""Inward rectifier K(+) channel Kir6.2""(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 11(gene name synonym)"	psi-mi:ugpc_yerpe(display_long)|uniprotkb:ugpC(gene name)|psi-mi:ugpC(display_short)|uniprotkb:YPO3793(locus name)|uniprotkb:y0437(locus name)|uniprotkb:YP_3256(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866550|imex:IM-13779-7231	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-58643N|ensembl:ENSG00000187486.7(gene)|ensembl:ENST00000339994.5(transcript)|go:""GO:0001508""(action potential)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0002931""(response to ischemia)|go:""GO:0003229""(ventricular cardiac muscle tissue development)|go:""GO:0005249""(voltage-gated potassium channel activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0008282""(inward rectifying potassium channel)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0014704""(intercalated disc)|go:""GO:0015272""(ATP-activated inward rectifier potassium channel activity)|go:""GO:0019829""(ATPase-coupled monoatomic cation transmembrane transporter activity)|go:""GO:0030315""(T-tubule)|go:""GO:0030506""(ankyrin binding)|go:""GO:0030673""(axolemma)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0032355""(response to estradiol)|go:""GO:0033198""(response to ATP)|go:""GO:0033574""(response to testosterone)|go:""GO:0034765""(regulation of monoatomic ion transmembrane transport)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0046676""(negative regulation of insulin secretion)|go:""GO:0050796""(regulation of insulin secretion)|go:""GO:0050877""(nervous system process)|go:""GO:0061762""(CAMKK-AMPK signaling cascade)|go:""GO:0070852""(cell body fiber)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071805""(potassium ion transmembrane transport)|go:""GO:0098662""(inorganic cation transmembrane transport)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099508""(voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1904638""(response to resveratrol)|go:""GO:1990573""(potassium ion import across plasma membrane)|interpro:IPR003279(Potassium channel, inwardly rectifying, Kir6.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|rcsb pdb:6C3O|rcsb pdb:6C3P|rcsb pdb:7S5T|rcsb pdb:7S5X|rcsb pdb:7S5Y|rcsb pdb:7S5Z|rcsb pdb:7S60|rcsb pdb:7S61|reactome:R-HSA-1296025|reactome:R-HSA-382556|reactome:R-HSA-422356|reactome:R-HSA-5578775|reactome:R-HSA-5678420|reactome:R-HSA-5683177|refseq:NP_000516.3|refseq:NP_001159762.1|efo:""Orphanet:276580""|efo:""Orphanet:276603""|efo:""Orphanet:552""|efo:""Orphanet:79134""|efo:""Orphanet:79644""|efo:""Orphanet:99885""|efo:""Orphanet:99886""|efo:""Orphanet:99989""|panther:PTHR11767(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR040582|interpro:IPR015855(ABC transporter, maltose/maltodextrin import, MalK)|interpro:IPR027417|refseq:WP_002211523.1|go:""GO:0001407""(glycerophosphodiester transmembrane transport)|go:""GO:0005524""(ATP binding)|go:""GO:0008643""(carbohydrate transport)|go:""GO:0015430""(ABC-type glycerol-3-phosphate transporter activity)|go:""GO:0015794""(glycerol-3-phosphate transmembrane transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055052""(""ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing"")|interpro:IPR047641|refseq:YP_002348670.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR43875(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:fEUbyHq+NZkCeuMZgT+oo3x1WyM9606	rogid:NtRUgbRI2HE2UzUkxbSvyMnRkao632	intact-crc:CA0E0C9BEC8EDD2C|rigid:4HHLomaEcZ33ZyWWU8NUzSC21Wg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q02556	uniprotkb:A0A5P8YEG1	intact:EBI-2866563|uniprotkb:A0AV82|ensembl:ENSP00000268638.4|ensembl:ENSP00000456992.2|ensembl:ENSP00000512953.1	intact:EBI-2852022|uniprotkb:Q74UV9|uniprotkb:A0A2U2GXG2|uniprotkb:A0A0H2W3X6|uniprotkb:Q7CHY3|uniprotkb:A0A384KW77	psi-mi:irf8_human(display_long)|uniprotkb:IRF8(gene name)|psi-mi:IRF8(display_short)|uniprotkb:ICSBP1(gene name synonym)|uniprotkb:Interferon consensus sequence-binding protein(gene name synonym)	psi-mi:a0a5p8yeg1_yerpe(display_long)|uniprotkb:flaS(gene name)|psi-mi:flaS(display_short)|uniprotkb:flaW(gene name synonym)|uniprotkb:flgK(gene name synonym)|uniprotkb:YPO1808(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866575|imex:IM-13779-7229	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000140968.12(gene)|ensembl:ENST00000268638.10(transcript)|ensembl:ENST00000564803.6(transcript)|ensembl:ENST00000696887.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0002273""(plasmacytoid dendritic cell differentiation)|go:""GO:0002314""(germinal center B cell differentiation)|go:""GO:0002316""(follicular B cell differentiation)|go:""GO:0002376""(immune system process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006909""(phagocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0006955""(immune response)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0032479""(regulation of type I interferon production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042832""(defense response to protozoan)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0097028""(dendritic cell differentiation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_002154.1|efo:""Orphanet:319600""|panther:PTHR11949(orthology-group)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR002371(Flagellar hook-associated protein)|refseq:WP_002211119.1|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009424""(bacterial-type flagellum hook)|go:""GO:0044780""(bacterial-type flagellum assembly)|interpro:IPR053927|interpro:IPR049119|refseq:YP_002346803.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Vbi/gEHdrX0ohwqmLkQ5s7O5M/Q9606	rogid:pNXjB/cj8ecgLe9j2NLbgGL8sgw632	intact-crc:CD3974572452ADDA|rigid:k5k5ZQJDrpyUTM+pg4JB+Fwwk2Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q02556	uniprotkb:Q8D1M8	intact:EBI-2866563|uniprotkb:A0AV82|ensembl:ENSP00000268638.4|ensembl:ENSP00000456992.2|ensembl:ENSP00000512953.1	intact:EBI-2843956	psi-mi:irf8_human(display_long)|uniprotkb:IRF8(gene name)|psi-mi:IRF8(display_short)|uniprotkb:ICSBP1(gene name synonym)|uniprotkb:Interferon consensus sequence-binding protein(gene name synonym)	psi-mi:q8d1m8_yerpe(display_long)|uniprotkb:y0257(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866568|imex:IM-13779-7230	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000140968.12(gene)|ensembl:ENST00000268638.10(transcript)|ensembl:ENST00000564803.6(transcript)|ensembl:ENST00000696887.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0002273""(plasmacytoid dendritic cell differentiation)|go:""GO:0002314""(germinal center B cell differentiation)|go:""GO:0002316""(follicular B cell differentiation)|go:""GO:0002376""(immune system process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006909""(phagocytosis)|go:""GO:0006914""(autophagy)|go:""GO:0006955""(immune response)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0032479""(regulation of type I interferon production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042832""(defense response to protozoan)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0097028""(dendritic cell differentiation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_002154.1|efo:""Orphanet:319600""|panther:PTHR11949(orthology-group)"	interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)|interpro:IPR050708	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Vbi/gEHdrX0ohwqmLkQ5s7O5M/Q9606	rogid:CV6eFVldIgYFQRKvjlqv9/IE4do632	intact-crc:C464A8808983FB83|rigid:zDswnGnLIBnE7klwW6XMKhFIYmw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CLB2	uniprotkb:P21399	intact:EBI-2866604|uniprotkb:Q74YB0	intact:EBI-2847111|uniprotkb:Q5VZA7|uniprotkb:Q14652|uniprotkb:D3DRK7|ensembl:ENSP00000309477.5|ensembl:ENSP00000369255.1|ensembl:ENSP00000438733.2	"psi-mi:ligb_yerpe(display_long)|uniprotkb:ligB(gene name)|psi-mi:ligB(display_short)|uniprotkb:""Polydeoxyribonucleotide synthase [NAD(+)] B""(gene name synonym)|uniprotkb:YPO0041(locus name)|uniprotkb:YP_0042(locus name)|uniprotkb:y0100(locus name)"	psi-mi:acohc_human(display_long)|uniprotkb:ACO1(gene name)|psi-mi:ACO1(display_short)|uniprotkb:IREB1(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Ferritin repressor protein(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866601|imex:IM-13779-7236	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020923|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|refseq:WP_002215674.1|interpro:IPR050326|go:""GO:0003911""(""DNA ligase (NAD+) activity"")|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|refseq:YP_002345137.1|panther:PTHR47810(orthology-group)"	"refseq:XP_011516190.1|refseq:NP_001265281.1|refseq:NP_002188.1|refseq:XP_005251533.1|ensembl:ENSG00000122729.19(gene)|ensembl:ENST00000309951.8(transcript)|ensembl:ENST00000379923.5(transcript)|ensembl:ENST00000541043.5(transcript)|go:""GO:0000900""(mRNA regulatory element binding translation repressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006101""(citrate metabolic process)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010040""(""response to iron(II) ion"")|go:""GO:0030350""(iron-responsive element binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0050892""(intestinal absorption)|go:""GO:0051536""(iron-sulfur cluster binding)|go:""GO:0051538""(3 iron, 4 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR036008|interpro:IPR044137|mint:P21399|rcsb pdb:2B3X|rcsb pdb:2B3Y|reactome:R-HSA-389542|reactome:R-HSA-917937|panther:PTHR11670(orthology-group)|ensembl:ENSP00000309477.5|ensembl:ENSP00000369255.1|ensembl:ENSP00000438733.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GeGJmGHRIDTZu+RtlycljsNaaow632	rogid:hcZPPf3fTfqol8El1L5kwVEljyY9606	intact-crc:1E4513B1EC222EF8|rigid:EvcOhLDPIH0ivOC/YelMZRB1fAo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W496	uniprotkb:Q15306	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	intact:EBI-751345|uniprotkb:Q5VUI7|uniprotkb:Q99660|ensembl:ENSP00000370343.4|intact:EBI-28969842	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	psi-mi:irf4_human(display_long)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:Multiple myeloma oncogene 1(gene name synonym)|uniprotkb:IRF4(gene name)|psi-mi:IRF4(display_short)|uniprotkb:MUM1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866582|imex:IM-13779-7232	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"ensembl:ENSG00000137265.16(gene)|ensembl:ENST00000380956.9(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000786""(nucleosome)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0002376""(immune system process)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032743""(positive regulation of interleukin-2 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0042110""(T cell activation)|go:""GO:0042832""(defense response to protozoan)|go:""GO:0043011""(myeloid dendritic cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q15306|rcsb pdb:2DLL|rcsb pdb:6TD4|rcsb pdb:7JM4|rcsb pdb:7O56|rcsb pdb:7OGS|rcsb pdb:7OOT|rcsb pdb:7RH2|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9725371|reactome:R-HSA-9824585|refseq:NP_001182215.1|refseq:NP_002451.2|efo:""Orphanet:3452""|panther:PTHR11949(orthology-group)|ensembl:ENSP00000370343.4|ensembl:ENST00000696871.1|ensembl:ENSP00000512940.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	rogid:32kCHCtSe1riCkTgTnnr5gMipfs9606	intact-crc:77DB4B0E886E951F|rigid:uzkl+8tixlL5YU3QT5DepsMaa9Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG0	uniprotkb:P46940	intact:EBI-2842527|uniprotkb:Q8CKL4|uniprotkb:Q0WIA2|uniprotkb:Q74QH2	intact:EBI-297509|intact:EBI-25601492|uniprotkb:A7MBM3|ensembl:ENSP00000268182.5	psi-mi:agua_yerpe(display_long)|uniprotkb:aguA(gene name)|psi-mi:aguA(display_short)|uniprotkb:Agmatine iminohydrolase(gene name synonym)|uniprotkb:YPO0939(locus name)|uniprotkb:y3325(locus name)|uniprotkb:YP_3503(locus name)	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866620|imex:IM-13779-7234	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017754(Agmatine deiminase)|interpro:IPR007466(Peptidyl-arginine deiminase, Porphyromonas-type)|go:""GO:0004668""(protein-arginine deiminase activity)|go:""GO:0009446""(putrescine biosynthetic process)|go:""GO:0047632""(agmatine deiminase activity)|refseq:YP_002345986.1|panther:PTHR31377(orthology-group)"	"ensembl:ENSG00000140575.13(gene)|ensembl:ENST00000268182.10(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010761""(fibroblast migration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030424""(axon)|go:""GO:0030426""(growth cone)|go:""GO:0030496""(midbody)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035305""(negative regulation of dephosphorylation)|go:""GO:0036057""(slit diaphragm)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0043005""(neuron projection)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0051015""(actin filament binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070836""(caveola assembly)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0072015""(podocyte development)|go:""GO:1903479""(mitotic actomyosin contractile ring assembly actin filament organization)|go:""GO:1990138""(neuron projection extension)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N|panther:PTHR14149(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:wqVmguxc+OwAcDUbyMd1UcCWH/o632	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	intact-crc:914C4BD542D125DE|rigid:LbfHL9n8K0qfUE+qltTLKB7zkU4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q58WW2	uniprotkb:Q8ZES0	intact:EBI-2559044|ensembl:ENSP00000311949.6|uniprotkb:Q8TB19|uniprotkb:Q8IXH3|uniprotkb:A2A295|uniprotkb:Q7L8I0|uniprotkb:B4DNB8	intact:EBI-2845458|uniprotkb:Q0WF73	psi-mi:dcaf6_human(display_long)|uniprotkb:DCAF6(gene name)|psi-mi:DCAF6(display_short)|uniprotkb:IQWD1(gene name synonym)|uniprotkb:Nuclear receptor interaction protein(gene name synonym)|uniprotkb:IQ motif and WD repeat-containing protein 1(gene name synonym)|uniprotkb:Androgen receptor complex-associated protein(gene name synonym)|uniprotkb:MSTP055(orf name)	psi-mi:y2083_yerpe(display_long)|uniprotkb:YPO2083(locus name)|uniprotkb:y2228(locus name)|uniprotkb:YP_1926(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866613|imex:IM-13779-7235	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143164.16(gene)|ensembl:ENST00000312263.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0080008""(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR045151|mint:Q58WW2|rcsb pdb:3I7O|reactome:R-HSA-8951664|refseq:NP_001017977.1|refseq:NP_001185885.1|refseq:NP_001185886.1|refseq:NP_060912.2|dip:DIP-44678N|panther:PTHR15574(orthology-group)"	interpro:IPR008228(Uncharacterised conserved protein UCP006173)|interpro:IPR005358(Protein of unknown function UPF0153)|refseq:WP_002211739.1|refseq:YP_002347065.1|panther:PTHR37421(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/25	rogid:1CtoPWPj6fdryvDlC46pXiUguDc9606	rogid:p1yW4rWt+CvstvpxbwtZ4Y1jXAU632	intact-crc:60D8F6EC4D67F5FD|rigid:0O3wXJALdMv522Up0UocW08Sxks	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYS8	uniprotkb:P14316	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218.3|ensembl:ENSP00000424552.2|ensembl:ENSP00000512878.1|ensembl:ENSP00000512918.1|ensembl:ENSP00000512920.1|ensembl:ENSP00000512922.1|ensembl:ENSP00000512923.1|ensembl:ENSP00000512925.1|ensembl:ENSP00000512927.1|ensembl:ENSP00000512954.1	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866594|imex:IM-13779-7233	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	"refseq:NP_002190.2|ensembl:ENSG00000168310.12(gene)|ensembl:ENST00000393593.8(transcript)|ensembl:ENST00000504340.2(transcript)|ensembl:ENST00000510814.6(transcript)|ensembl:ENST00000696840.1(transcript)|ensembl:ENST00000696841.1(transcript)|ensembl:ENST00000696843.1(transcript)|ensembl:ENST00000696845.1(transcript)|ensembl:ENST00000696846.1(transcript)|ensembl:ENST00000696849.1(transcript)|ensembl:ENST00000696851.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0002376""(immune system process)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008283""(cell population proliferation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051607""(defense response to virus)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:P14316|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231|panther:PTHR11949(orthology-group)|ensembl:ENST00000696848.1|ensembl:ENSP00000512924.1|ensembl:ENSP00000512925.1|ensembl:ENSP00000512927.1|ensembl:ENST00000696853.1|ensembl:ENSP00000512929.1|ensembl:ENSP00000377218.3|ensembl:ENSP00000512878.1|ensembl:ENSP00000424552.2|ensembl:ENSP00000512918.1|ensembl:ENSP00000512954.1|ensembl:ENSP00000512920.1|ensembl:ENSP00000512922.1|ensembl:ENSP00000512923.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	intact-crc:2655707887BCF43E|rigid:eNRKyZ0usqeIE4Fl/oz493lTZwk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GZX8	uniprotkb:Q9UNL4	intact:EBI-2843751|uniprotkb:Q74V95|uniprotkb:A0A0H2W3N0|uniprotkb:Q7CHR8|uniprotkb:Q0WGN7|uniprotkb:A0A384KT94	intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024.4	psi-mi:a0a2u2gzx8_yerpe(display_long)|uniprotkb:YPO1535(locus name)	psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866667|imex:IM-13779-7239	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000522(Bacterial transport system permease protein)|refseq:WP_002211881.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR037294|refseq:YP_002346551.1"	"refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|ensembl:ENSG00000111653.20(gene)|ensembl:ENST00000396807.8(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006473""(protein acetylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0035064""(methylated histone binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045926""(negative regulation of growth)|go:""GO:0046872""(metal ion binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0140889""(DNA replication-dependent chromatin disassembly)|go:""GO:1902164""(obsolete positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:1902749""(regulation of cell cycle G2/M phase transition)|go:""GO:2000278""(regulation of DNA biosynthetic process)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|dip:DIP-42222N|panther:PTHR10333(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:l+psx95jXdNVBQMnKWDbWE5epic632	rogid:71DYqPEISrr06/kbSTCdA3J23NU9606	intact-crc:2F342EC15020AE21|rigid:QeoJIhr/Ku8jCuWSiqDTRq41CCU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15260	uniprotkb:A0A3N4B3A1	intact:EBI-1030755|uniprotkb:Q53Y96|uniprotkb:E1P587|uniprotkb:B4DFT7|ensembl:ENSP00000356713.5	intact:EBI-2846733|uniprotkb:Q74VL0|uniprotkb:A0A0H2W474|uniprotkb:Q7CHE8|uniprotkb:A0A384KI85	psi-mi:ingr1_human(display_long)|uniprotkb:IFNGR1(gene name)|psi-mi:IFNGR1(display_short)|uniprotkb:CDw119(gene name synonym)|uniprotkb:Interferon gamma receptor alpha-chain(gene name synonym)	psi-mi:a0a3n4b3a1_yerpe(display_long)|uniprotkb:fpr(gene name)|psi-mi:fpr(display_short)|uniprotkb:fruB(gene name synonym)|uniprotkb:fruF(gene name synonym)|uniprotkb:YPO1298(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866647|imex:IM-13779-7241	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-47N|efo:""Orphanet:117""|efo:""Orphanet:319569""|efo:""Orphanet:319581""|efo:""Orphanet:99898""|ensembl:ENSG00000027697.16(gene)|ensembl:ENST00000367739.9(transcript)|go:""GO:0001774""(microglial cell activation)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0004906""(type II interferon receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0009615""(response to virus)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019955""(cytokine binding)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0038196""(type III interferon-mediated signaling pathway)|go:""GO:0048143""(astrocyte activation)|go:""GO:0051607""(defense response to virus)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0098586""(cellular response to virus)|go:""GO:1900222""(negative regulation of amyloid-beta clearance)|go:""GO:1902004""(positive regulation of amyloid-beta formation)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008355(Interferon-gamma receptor alpha chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR021126|interpro:IPR036116|interpro:IPR050650|mint:P15260|rcsb pdb:1FG9|rcsb pdb:1FYH|rcsb pdb:1JRH|rcsb pdb:6E3K|rcsb pdb:6E3L|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9679191|reactome:R-HSA-9732724|refseq:NP_000407.1|panther:PTHR20859(orthology-group)"	"interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR002114(Phosphotransferase system, HPr serine phosphorylation site)|refseq:WP_002208799.1|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0090563""(protein-phosphocysteine-sugar phosphotransferase activity)|interpro:IPR035895|refseq:YP_002346323.1|interpro:IPR050893|panther:PTHR30181(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:lE0NJNR3ItPnoiugDg2ZJno2okg9606	rogid:Vp2FIu9BGFwhpfjQL30qgAgLZPU632	intact-crc:013D2C866FFAF2DE|rigid:h98Xay92Ea9DLVKWMYCcpWjyJNw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94829	uniprotkb:A0A380PL54	intact:EBI-747310|uniprotkb:Q7LC04|uniprotkb:Q96HS3|uniprotkb:Q9H8N3|uniprotkb:Q9UFR1|uniprotkb:Q5T4X3|ensembl:ENSP00000361418.3|uniprotkb:D3DPY4	intact:EBI-2847486|uniprotkb:Q74PZ0|uniprotkb:Q0WJM2|uniprotkb:Q7CG61|uniprotkb:A0A384KFY6	psi-mi:ipo13_human(display_long)|uniprotkb:Ran-binding protein 13(gene name synonym)|uniprotkb:Karyopherin-13(gene name synonym)|uniprotkb:IPO13(gene name)|psi-mi:IPO13(display_short)|uniprotkb:KIAA0724(gene name synonym)|uniprotkb:RANBP13(gene name synonym)	psi-mi:a0a380pl54_yerpe(display_long)|uniprotkb:b4388(gene name)|psi-mi:b4388(display_short)|uniprotkb:serB(gene name synonym)|uniprotkb:O-phosphoserine phosphohydrolase(gene name synonym)|uniprotkb:YPO0442(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866627|imex:IM-13779-7237	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055467.3|ensembl:ENSG00000117408.11(gene)|ensembl:ENST00000372343.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0031267""(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040520|interpro:IPR040709|interpro:IPR040944|interpro:IPR051345|mint:O94829|rcsb pdb:2X19|rcsb pdb:2XWU|rcsb pdb:3ZJY|panther:PTHR12363(orthology-group)"	"interpro:IPR023214|refseq:WP_002209219.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006564""(L-serine biosynthetic process)|go:""GO:0036424""(L-phosphoserine phosphatase activity)|interpro:IPR036412|interpro:IPR041449|interpro:IPR004469(Phosphoserine phosphatase SerB)|refseq:YP_002345516.1|interpro:IPR050582|panther:PTHR43344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HC5CjdyfnwoVeE9JNHgicwFybWc9606	rogid:geOUaVXaO28Rw1OHbz2UDW1vFEg632	intact-crc:A679770A3333FF48|rigid:jMWt6ohwnoKYtuec8PKxuOjys+I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NV88	uniprotkb:Q8D092	intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065.1	intact:EBI-2845361	psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym)	psi-mi:q8d092_yerpe(display_long)|uniprotkb:fcuA(gene name)|psi-mi:fcuA(display_short)|uniprotkb:y2556(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866640|imex:IM-13779-7238	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299.15(gene)|ensembl:ENST00000521022.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016180""(snRNA processing)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0032039""(integrator complex)|go:""GO:0034243""(regulation of transcription elongation by RNA polymerase II)|go:""GO:0034472""(snRNA 3'-end processing)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|interpro:IPR048660|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|rcsb pdb:7PKS|rcsb pdb:7YCX|rcsb pdb:8R22|rcsb pdb:8R23|rcsb pdb:8R2D|rcsb pdb:8RBX|rcsb pdb:8RBZ|rcsb pdb:8RC4|rcsb pdb:8UIB|reactome:R-HSA-6807505|panther:PTHR46094(orthology-group)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR010105(TonB-dependent siderophore receptor)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606	rogid:7oNsiLRBKD+1PyrMueBNpf/zdLs632	intact-crc:A8F9143E4A566CB3|rigid:jRqEhjx60yDeCvSa8/u3Km2ihog	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WYH8	uniprotkb:Q8ZAQ2	intact:EBI-488533|ensembl:ENSP00000322142.7|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54	intact:EBI-2860892|uniprotkb:Q0WAR9	psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short)	psi-mi:thic_yerpe(display_long)|uniprotkb:thiC(gene name)|psi-mi:thiC(display_short)|uniprotkb:YP_3102(locus name)|uniprotkb:Hydroxymethylpyrimidine phosphate synthase(gene name synonym)|uniprotkb:YPO3739(locus name)|uniprotkb:y0491(locus name)|uniprotkb:Thiamine biosynthesis protein ThiC(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866654|imex:IM-13779-7240	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168395.16(gene)|ensembl:ENST00000313552.11(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006473""(protein acetylation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0035064""(methylated histone binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045926""(negative regulation of growth)|go:""GO:0046872""(metal ion binding)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0050793""(regulation of developmental process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070776""(MOZ/MORF histone acetyltransferase complex)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0140889""(DNA replication-dependent chromatin disassembly)|go:""GO:1903706""(regulation of hemopoiesis)|go:""GO:2000278""(regulation of DNA biosynthetic process)|go:""GO:2001235""(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_115705.2|panther:PTHR10333(orthology-group)|refseq:NP_001317091.1|dip:DIP-32511N"	"interpro:IPR002817(Thiamine biosynthesis protein ThiC)|refseq:WP_002210682.1|interpro:IPR025747|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0016830""(carbon-carbon lyase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR038521|interpro:IPR037509|refseq:YP_002348619.1|panther:PTHR30557(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dwJLwzNcL9866noaSFznDKeulRU9606	rogid:RVZL9aFEqXV/KORpQabcnqvxVkE632	intact-crc:F47A5614F468FF39|rigid:CcA1RR6pGOeDBekZ/69VjNUFWIY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:O00410	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219.3|ensembl:ENSP00000418393.1|ensembl:ENSP00000499125.1|intact:EBI-21353074	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866707|imex:IM-13779-7243	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"refseq:NP_002262.3|refseq:XP_005254109.1|refseq:XP_005254110.1|ensembl:ENSG00000065150.21(gene)|ensembl:ENST00000357602.7(transcript)|ensembl:ENST00000490680.5(transcript)|ensembl:ENST00000651721.2(transcript)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003723""(RNA binding)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0006610""(ribosomal protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0045736""(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0061608""(nuclear import signal receptor activity)|go:""GO:0071230""(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|refseq:XP_016876051.1|dip:DIP-41042N|panther:PTHR10527(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	intact-crc:2EB0486265C4E972|rigid:FqC7iShBQl1WNqqYXU72lwNL3Os	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A454XXH7	uniprotkb:P20839	intact:EBI-2851240|uniprotkb:Q74Y15|uniprotkb:A0A0H2W158|uniprotkb:Q7CFV5|uniprotkb:A0A384K924	intact:EBI-2866691|uniprotkb:A6NDW5|uniprotkb:Q96NU2|uniprotkb:B3KNP7|uniprotkb:A4D0Z7|uniprotkb:Q8N194|uniprotkb:B4DE09|uniprotkb:A4D0Z6|uniprotkb:A6NNI6|uniprotkb:B3KVM8|uniprotkb:C9JV30|uniprotkb:J3KNX8	psi-mi:a0a454xxh7_yerpe(display_long)|uniprotkb:YPO0168(locus name)	psi-mi:imdh1_human(display_long)|uniprotkb:IMPDH1(gene name)|psi-mi:IMPDH1(display_short)|uniprotkb:IMPD1(gene name synonym)|uniprotkb:IMPDH-I(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866700|imex:IM-13779-7244	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR027417|refseq:WP_002215686.1|interpro:IPR033186|refseq:YP_002345254.1|interpro:IPR051162|panther:PTHR30121(orthology-group)	"dip:DIP-60163N|go:""GO:0000166""(nucleotide binding)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003938""(IMP dehydrogenase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006177""(GMP biosynthetic process)|go:""GO:0006183""(GTP biosynthetic process)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P20839|rcsb pdb:1JCN|rcsb pdb:7RER|rcsb pdb:7RES|rcsb pdb:7RFE|rcsb pdb:7RFF|rcsb pdb:7RFG|rcsb pdb:7RFH|rcsb pdb:7RFI|rcsb pdb:7RGD|rcsb pdb:7RGI|rcsb pdb:7RGL|rcsb pdb:7RGM|rcsb pdb:7RGQ|rcsb pdb:8U7M|rcsb pdb:8U7Q|rcsb pdb:8U7V|rcsb pdb:8U8O|rcsb pdb:8U8Y|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191|reactome:R-HSA-9748787|refseq:NP_000874.2|refseq:NP_001096075.1|refseq:NP_001136045.1|refseq:NP_001136046.1|refseq:NP_001136047.1|refseq:NP_001136048.1|refseq:NP_001291450.1|refseq:NP_899066.1|refseq:XP_016867661.1|efo:""Orphanet:65""|efo:""Orphanet:791""|panther:PTHR11911(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7T8Io5VjMpoAGWF393x9GYtAK2w632	rogid:avFKvRBQHBqoWUp4+Zos6OsLqfA9606	intact-crc:197AEC197EAABCD5|rigid:OKTcuPBVD789zI4HvCjXIdaWGfo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14732	uniprotkb:Q8CKM5	intact:EBI-725233|uniprotkb:Q9UJT3|ensembl:ENSP00000269159.3|uniprotkb:B0YJ29	intact:EBI-2866681	"psi-mi:impa2_human(display_long)|uniprotkb:""Inositol-1(or 4)-monophosphatase 2""(gene name synonym)|uniprotkb:Myo-inositol monophosphatase A2(gene name synonym)|uniprotkb:IMPA2(gene name)|psi-mi:IMPA2(display_short)|uniprotkb:IMP.18P(gene name synonym)"	psi-mi:q8ckm5_yerpe(display_long)|uniprotkb:y3269(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866684|imex:IM-13779-7245	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055029.1|ensembl:ENSG00000141401.12(gene)|ensembl:ENST00000269159.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006020""(inositol metabolic process)|go:""GO:0006021""(inositol biosynthetic process)|go:""GO:0006796""(phosphate-containing compound metabolic process)|go:""GO:0007165""(signal transduction)|go:""GO:0008934""(inositol monophosphate 1-phosphatase activity)|go:""GO:0010226""(response to lithium ion)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|mint:O14732|rcsb pdb:2CZH|rcsb pdb:2CZI|rcsb pdb:2CZK|rcsb pdb:2DDK|rcsb pdb:2FVZ|reactome:R-HSA-1855183|panther:PTHR20854(orthology-group)"	refseq:WP_002214784.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aNPodNmy97DStapDoe+oOkCD8X49606	rogid:nzKomD/m8a4VrQlGhE/SP0pvhko632	intact-crc:7992471A9016757F|rigid:CuBNEe1ljpPLZypIwoaXTcZjLkk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W1D0	uniprotkb:P17181	intact:EBI-2850611|uniprotkb:Q74XN0|uniprotkb:Q0WBY0|uniprotkb:A0A3N4B5H8|uniprotkb:Q7CKA0|uniprotkb:A0A384KPX7	intact:EBI-1547250|uniprotkb:Q53GW9|uniprotkb:Q53H11|uniprotkb:Q8WTZ2|uniprotkb:Q6PKD7|uniprotkb:Q7M4L2|uniprotkb:B4DNT3|uniprotkb:D3DSF0|uniprotkb:B2R6L9|ensembl:ENSP00000270139.3|ensembl:ENSP00000515348.1|ensembl:ENSP00000515372.1	psi-mi:a0a0h2w1d0_yerpe(display_long)|uniprotkb:YPO3312(locus name)	psi-mi:inar1_human(display_long)|uniprotkb:IFNAR1(gene name)|psi-mi:IFNAR1(display_short)|uniprotkb:IFNAR(gene name synonym)|uniprotkb:Type I interferon receptor 1(gene name synonym)|uniprotkb:Cytokine receptor family 2 member 1(gene name synonym)|uniprotkb:Cytokine receptor class-II member 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866674|imex:IM-13779-7242	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018485|interpro:IPR018484|interpro:IPR000577(Carbohydrate kinase, FGGY)|refseq:WP_002209440.1|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016301""(kinase activity)|interpro:IPR043129|interpro:IPR042016|refseq:YP_002348208.1"	"refseq:NP_000620.2|refseq:XP_005261021.1|dip:DIP-57N|ensembl:ENSG00000142166.15(gene)|ensembl:ENST00000270139.8(transcript)|ensembl:ENST00000703515.1(transcript)|ensembl:ENST00000703556.1(transcript)|go:""GO:0004905""(type I interferon receptor activity)|go:""GO:0005764""(lysosome)|go:""GO:0005770""(late endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008269""(JAK pathway signal transduction adaptor activity)|go:""GO:0009615""(response to virus)|go:""GO:0019955""(cytokine binding)|go:""GO:0019962""(type I interferon binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0035457""(cellular response to interferon-alpha)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0098586""(cellular response to virus)|go:""GO:1901857""(positive regulation of cellular respiration)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR016669(Interferon-alpha/beta receptor 1)|interpro:IPR036116|interpro:IPR050650|mint:P17181|rcsb pdb:3S98|rcsb pdb:3SE3|rcsb pdb:3SE4|rcsb pdb:4PO6|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191|reactome:R-HSA-9705671|reactome:R-HSA-9833109|panther:PTHR20859(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TkbiVPrlraU0BBleepm9BhezvWk632	rogid:DuOuIr85nya6Ti494f43fftNRyo9606	intact-crc:ED19BE14658495AB|rigid:zw9cmBItj1TZ+kfnuZwNchiSrnA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12906	uniprotkb:A0A2S9PFE9	intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|uniprotkb:G5E9M5|intact:EBI-10970055|ensembl:ENSP00000468156.1	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym)	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866721|imex:IM-13779-7247	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|panther:PTHR45762(orthology-group)|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N|ensembl:ENSG00000129351.18(gene)|ensembl:ENST00000590261.5(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0016020""(membrane)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051607""(defense response to virus)|go:""GO:0160091""(spliceosome-depend formation of circular RNA)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|interpro:IPR049401|interpro:IPR049402|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|rcsb pdb:7RJM|rcsb pdb:7RJQ|reactome:R-HSA-9762293|reactome:R-HSA-9833482"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	intact-crc:3D4D5995653CEF8C|rigid:Cl8082ASgVWxhIeqVyDVXVmCrOs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D195	uniprotkb:P40189	intact:EBI-2854725|uniprotkb:Q74XR6	intact:EBI-1030834|uniprotkb:Q9UQ41|uniprotkb:A0N0L4|uniprotkb:Q5FC04|ensembl:ENSP00000370698.2|ensembl:ENSP00000462158.1|ensembl:ENSP00000513858.1	psi-mi:q8d195_yerpe(display_long)|uniprotkb:tdh2(gene name)|psi-mi:tdh2(display_short)|uniprotkb:YP_0335(locus name)|uniprotkb:y0838(locus name)	psi-mi:il6rb_human(display_long)|uniprotkb:IL6ST(gene name)|psi-mi:IL6ST(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:CDw130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866735|imex:IM-13779-7249	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050129|interpro:IPR020843|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR036291"	"efo:""Orphanet:656283""|efo:""Orphanet:656300""|efo:""Orphanet:656313""|dip:DIP-95N|ensembl:ENSG00000134352.21(gene)|ensembl:ENST00000381298.7(transcript)|ensembl:ENST00000502326.7(transcript)|ensembl:ENST00000698645.1(transcript)|go:""GO:0002675""(positive regulation of acute inflammatory response)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0004897""(ciliary neurotrophic factor receptor activity)|go:""GO:0004921""(interleukin-11 receptor activity)|go:""GO:0005127""(ciliary neurotrophic factor receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0005896""(interleukin-6 receptor complex)|go:""GO:0005900""(oncostatin-M receptor complex)|go:""GO:0005977""(glycogen metabolic process)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010613""(positive regulation of cardiac muscle hypertrophy)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019838""(growth factor binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0019970""(interleukin-11 binding)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030425""(dendrite)|go:""GO:0034097""(response to cytokine)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038165""(oncostatin-M-mediated signaling pathway)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045121""(membrane raft)|go:""GO:0045509""(interleukin-27 receptor activity)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0048711""(positive regulation of astrocyte differentiation)|go:""GO:0048861""(leukemia inhibitory factor signaling pathway)|go:""GO:0060576""(intestinal epithelial cell development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0070104""(negative regulation of interleukin-6-mediated signaling pathway)|go:""GO:0070106""(interleukin-27-mediated signaling pathway)|go:""GO:0070110""(ciliary neurotrophic factor receptor complex)|go:""GO:0070120""(ciliary neurotrophic factor-mediated signaling pathway)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0097696""(cell surface receptor signaling pathway via STAT)|go:""GO:1901731""(positive regulation of platelet aggregation)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|interpro:IPR050379|mint:P40189|rcsb pdb:1BJ8|rcsb pdb:1BQU|rcsb pdb:1I1R|rcsb pdb:1P9M|rcsb pdb:1PVH|rcsb pdb:3L5H|rcsb pdb:3L5I|rcsb pdb:3L5J|rcsb pdb:7U7N|rcsb pdb:8D6A|rcsb pdb:8D74|rcsb pdb:8D7R|rcsb pdb:8D82|rcsb pdb:8D85|rcsb pdb:8DPS|rcsb pdb:8DPT|rcsb pdb:8DPU|rcsb pdb:8UPA|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-6788467|reactome:R-HSA-8984722|reactome:R-HSA-9020956|refseq:NP_001177910.1|refseq:NP_002175.2|refseq:NP_786943.1|panther:PTHR23036(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aFN8BkXf76lWZDW1xzdtvYClPGI632	rogid:0DhlsbEh3ZiKomQFf+5mjd6hUOM9606	intact-crc:2430E45DE523BC16|rigid:7htbOgABBGDJBVIhFPhmhbQoAZA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00629	uniprotkb:Q8D1P8	intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|uniprotkb:A8K4S6|uniprotkb:D3DNM2|ensembl:ENSP00000334373.4	intact:EBI-2841883	psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym)	psi-mi:q8d1p8_yerpe(display_long)|uniprotkb:tcaA1(gene name)|psi-mi:tcaA1(display_short)|uniprotkb:y0183(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866714|imex:IM-13779-7246	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002259.1|panther:PTHR23316(orthology-group)|ensembl:ENSG00000186432.10(gene)|ensembl:ENST00000334256.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006607""(NLS-bearing protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0010467""(gene expression)|go:""GO:0014046""(dopamine secretion)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042564""(NLS-dependent protein nuclear import complex)|go:""GO:0061608""(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RFY|rcsb pdb:7RG5|rcsb pdb:8FUB|rcsb pdb:8FZM|rcsb pdb:8HKW|reactome:R-HSA-1169408|reactome:R-HSA-168276|dip:DIP-32982N"	interpro:IPR018003	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/cng/xZ42E2juzHNOpuQTP+amx89606	rogid:LfA2Lz71pTe9HDOA0UOS0/RgEsY632	intact-crc:3963E972240A760F|rigid:dAqjxpGQ/qXkmDqJr4J4isITOxY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLD8	uniprotkb:P30740	intact:EBI-2851532|uniprotkb:Q74SW5	intact:EBI-2831526|uniprotkb:Q53FB9|uniprotkb:A8K5L2|uniprotkb:Q5W0E1|uniprotkb:Q9UDF8|uniprotkb:B4DNT0|ensembl:ENSP00000370115.5	psi-mi:q8cld8_yerpe(display_long)|uniprotkb:icmF2(gene name)|psi-mi:icmF2(display_short)|uniprotkb:YP_2442(locus name)|uniprotkb:y1553(locus name)	psi-mi:ileu_human(display_long)|uniprotkb:SERPINB1(gene name)|psi-mi:SERPINB1(display_short)|uniprotkb:ELANH2(gene name synonym)|uniprotkb:MNEI(gene name synonym)|uniprotkb:PI2(gene name synonym)|uniprotkb:Monocyte/neutrophil elastase inhibitor(gene name synonym)|uniprotkb:Peptidase inhibitor 2(gene name synonym)|uniprotkb:Serpin B1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866728|imex:IM-13779-7250	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010623(Protein of unknown function DUF1215)|interpro:IPR009612(ImcF-related)|interpro:IPR017731(Type VI secretion system, IcmF)|interpro:IPR025743|interpro:IPR027417|go:""GO:0016020""(membrane)|interpro:IPR053156"	"refseq:XP_011512635.1|refseq:XP_011512636.1|refseq:NP_109591.1|ensembl:ENSG00000021355.13(gene)|ensembl:ENST00000380739.6(transcript)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005769""(early endosome)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0016020""(membrane)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0044194""(cytolytic granule)|go:""GO:0044342""(type B pancreatic cell proliferation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:4GA7|reactome:R-HSA-6798695|panther:PTHR11461(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:w2fthS2L39XGe86y6WdmUYcCZvo632	rogid:5IolAmA+BrS4XHZZEQgf05kA4pE9606	intact-crc:BA7548CDD495BA03|rigid:yrRSmYFBB6TKgX5yo6QwZDvLPvg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLT3	uniprotkb:P24394	intact:EBI-2845884	intact:EBI-367009|uniprotkb:Q96P01|uniprotkb:Q9H181|uniprotkb:Q9H182|uniprotkb:Q9H183|uniprotkb:Q9H184|uniprotkb:Q9H185|uniprotkb:Q9H186|uniprotkb:Q9H187|uniprotkb:Q9H188|uniprotkb:B4E076|uniprotkb:B9EKU8|uniprotkb:H3BSY5|ensembl:ENSP00000379111.2|ensembl:ENSP00000441667.2	psi-mi:q8clt3_yerpe(display_long)|uniprotkb:y0272(locus name)	psi-mi:il4ra_human(display_long)|uniprotkb:IL4R(gene name)|psi-mi:IL4R(display_short)|uniprotkb:582J2.1(orf name)|uniprotkb:IL4RA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866742|imex:IM-13779-7248	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010657(ImpA, N-terminal)|interpro:IPR017739(Type VI secretion system-associated, VCA0119)	"refseq:NP_001244336.1|refseq:NP_000409.1|refseq:NP_001244335.1|ensembl:ENSG00000077238.14(gene)|ensembl:ENST00000395762.7(transcript)|ensembl:ENST00000543915.6(transcript)|go:""GO:0002532""(production of molecular mediator involved in inflammatory response)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0004913""(interleukin-4 receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0042832""(defense response to protozoan)|go:""GO:0043032""(positive regulation of macrophage activation)|go:""GO:0043235""(receptor complex)|go:""GO:0043306""(positive regulation of mast cell degranulation)|go:""GO:0045063""(T-helper 1 cell differentiation)|go:""GO:0045064""(T-helper 2 cell differentiation)|go:""GO:0045626""(negative regulation of T-helper 1 cell differentiation)|go:""GO:0045630""(positive regulation of T-helper 2 cell differentiation)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1901741""(positive regulation of myoblast fusion)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015319(Interleukin-4 receptor alpha chain, N-terminal)|interpro:IPR036116|mint:P24394|rcsb pdb:1IAR|rcsb pdb:1IRS|rcsb pdb:3BPL|rcsb pdb:3BPN|rcsb pdb:3BPO|rcsb pdb:5E4E|rcsb pdb:6OEL|rcsb pdb:6WGL|rcsb pdb:8K4Q|reactome:R-HSA-6785807|refseq:XP_011544127.1|refseq:XP_011544128.1|refseq:XP_011544129.1|dip:DIP-3223N|panther:PTHR23037(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6TnQPOOe3FeEE1LWQVyzY/Oug6E632	rogid:18E1cLQsvHGc0WRFqUzuGssLVg09606	intact-crc:B2C5BA55F3EB3949|rigid:1Tbukjk5pnR9ic6oW/9TJkMzO0E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14005	uniprotkb:A0A0H2W8E2	intact:EBI-2831580|uniprotkb:A8MU65|uniprotkb:B9EGR6|uniprotkb:Q6ZMQ7|uniprotkb:Q9UP18|uniprotkb:A6NM20|uniprotkb:Q16435|uniprotkb:Q6VVE6|uniprotkb:B5TY35|uniprotkb:H3BVH5|ensembl:ENSP00000508085.1|intact:EBI-28973443	intact:EBI-2845898|uniprotkb:Q74Q33|uniprotkb:Q0WJG5|uniprotkb:Q7CG91|uniprotkb:A0A2U2H085|uniprotkb:A0A384KB95	psi-mi:il16_human(display_long)|uniprotkb:IL16(gene name)|psi-mi:IL16(display_short)	psi-mi:a0a0h2w8e2_yerpe(display_long)|uniprotkb:YPO0500(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866788|imex:IM-13779-7252	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011519822.1|refseq:NP_001165599.1|refseq:NP_004504.3|refseq:NP_757366.2|refseq:XP_005254403.1|refseq:XP_016877630.1|refseq:XP_016877631.1|ensembl:ENSG00000172349.19(gene)|ensembl:ENST00000683961.1(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006955""(immune response)|go:""GO:0016607""(nuclear speck)|go:""GO:0030595""(leukocyte chemotaxis)|go:""GO:0032730""(positive regulation of interleukin-1 alpha production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050930""(induction of positive chemotaxis)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0090543""(Flemming body)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|interpro:IPR055287|mint:Q14005|rcsb pdb:1I16|rcsb pdb:1X6D|rcsb pdb:5FB8|reactome:R-HSA-449836|dip:DIP-6006N|panther:PTHR48396(orthology-group)"	interpro:IPR008312(Uncharacterised conserved protein UCP028301)|refseq:WP_002210481.1|refseq:YP_002345573.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3kcSA6a4uuNCcII2VNJRIVUGY+89606	rogid:r1UlnEbb/K20reicDTxy4VHlP90632	intact-crc:5883AF58F90F6C0C|rigid:GwelL4P31E9vpqi8kqqNQS28qcE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P24001	uniprotkb:Q8CLP9	intact:EBI-2866752|uniprotkb:Q5VFH7|uniprotkb:Q5VFH8|uniprotkb:Q96GK9|uniprotkb:Q8WV38|uniprotkb:D3DUB0|uniprotkb:D3DUB2|uniprotkb:A8MPX0|uniprotkb:B4DJM1|uniprotkb:A6NNM0|uniprotkb:B8Q191|ensembl:ENSP00000380099.2|ensembl:ENSP00000431775.1|ensembl:ENSP00000449483.1	intact:EBI-2842545|uniprotkb:Q74XA7	psi-mi:il32_human(display_long)|uniprotkb:IL32(gene name)|psi-mi:IL32(display_short)|uniprotkb:NK4(gene name synonym)|uniprotkb:TAIF(gene name synonym)|uniprotkb:Natural killer cells protein 4(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-inducing factor(gene name synonym)	psi-mi:q8clp9_yerpe(display_long)|uniprotkb:y0640(locus name)|uniprotkb:YP_0539(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866749|imex:IM-13779-7251	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001295007.1|refseq:NP_001012649.1|refseq:NP_001012650.1|refseq:NP_001012651.1|refseq:NP_001012736.1|refseq:NP_004212.4|refseq:NP_001012652.1|refseq:NP_001012653.1|refseq:NP_001012654.1|dip:DIP-61119N|ensembl:ENSG00000008517.19(gene)|ensembl:ENST00000396890.6(transcript)|ensembl:ENST00000534507.5(transcript)|ensembl:ENST00000548476.5(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0006952""(defense response)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0034346""(positive regulation of type III interferon production)|go:""GO:1903901""(negative regulation of viral life cycle)|go:""GO:1905636""(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR028067|mint:P24001|reactome:R-HSA-449836|reactome:R-HSA-9013423|panther:PTHR48402(orthology-group)"	"interpro:IPR010854(Protein of unknown function DUF1471)|interpro:IPR025543|go:""GO:0016020""(membrane)|interpro:IPR036275"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nqJAdeihv1nYJsMpG+RklQbUqXM9606	rogid:XQKJPcIeoTca4sdu/iGk01aZb/E632	intact-crc:9405D4AC1E26CBD2|rigid:Q1tdo7t4AWzVJ6gO1dK+sWKa3ig	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31785	uniprotkb:Q8ZIC5	intact:EBI-80475|uniprotkb:Q5FC12|ensembl:ENSP00000363318.3	intact:EBI-2858331|uniprotkb:Q0WJ86	psi-mi:il2rg_human(display_long)|uniprotkb:IL2RG(gene name)|psi-mi:IL2RG(display_short)|uniprotkb:p64(gene name synonym)|uniprotkb:gammaC(gene name synonym)|uniprotkb:Interleukin-2 receptor subunit gamma(gene name synonym)	psi-mi:uxab_yerpe(display_long)|uniprotkb:uxaB(gene name)|psi-mi:uxaB(display_short)|uniprotkb:Tagaturonate dehydrogenase(gene name synonym)|uniprotkb:Tagaturonate reductase(gene name synonym)|uniprotkb:YPO0580(locus name)|uniprotkb:y3599(locus name)|uniprotkb:YP_2900(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866764|imex:IM-13779-7254	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR23036(orthology-group)|efo:""Orphanet:276""|efo:""Orphanet:39041""|dip:DIP-173N|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|ensembl:ENSG00000147168.14(gene)|ensembl:ENST00000374202.7(transcript)|go:""GO:0002335""(mature B cell differentiation)|go:""GO:0002361""(CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010467""(gene expression)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019725""(cellular homeostasis)|go:""GO:0019955""(cytokine binding)|go:""GO:0019976""(interleukin-2 binding)|go:""GO:0030098""(lymphocyte differentiation)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033089""(positive regulation of T cell differentiation in thymus)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0042010""(interleukin-15 receptor activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045579""(positive regulation of B cell differentiation)|go:""GO:0050766""(positive regulation of phagocytosis)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR048648|interpro:IPR053856|rcsb pdb:2B5I|rcsb pdb:2ERJ|rcsb pdb:3BPL|rcsb pdb:3QAZ|rcsb pdb:3QB7|rcsb pdb:4GS7|rcsb pdb:5M5E|rcsb pdb:6OEL|rcsb pdb:7S2R|rcsb pdb:8ENT|rcsb pdb:8EPA|reactome:R-HSA-1266695|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-8983432|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020958|reactome:R-HSA-912526|reactome:R-HSA-9701898|refseq:NP_000197.1"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR023668|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR013118(Mannitol dehydrogenase, C-terminal)|interpro:IPR013131(Mannitol dehydrogenase, N-terminal)|refseq:WP_002210409.1|go:""GO:0005829""(cytosol)|go:""GO:0008926""(mannitol-1-phosphate 5-dehydrogenase activity)|go:""GO:0009026""(tagaturonate reductase activity)|go:""GO:0019592""(mannitol catabolic process)|go:""GO:0019698""(D-galacturonate catabolic process)|interpro:IPR036291|refseq:YP_002345652.1|panther:PTHR30524(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Fz1gJI4Qk1jAguOQqWXbAWUb/8o9606	rogid:PyqKR9KbcVlhb9JsQra1Qvptw6Y632	intact-crc:FC16793687503533|rigid:ciiC3h1NrzsgQyH9fCiG+/r1cOM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CKP5	uniprotkb:P14784	intact:EBI-2866771|uniprotkb:Q74XF7	intact:EBI-2866779|uniprotkb:B2R765|ensembl:ENSP00000216223.5|ensembl:ENSP00000401020.2|ensembl:ENSP00000402685.2|ensembl:ENSP00000403731.2|ensembl:ENSP00000514005.1|ensembl:ENSP00000514009.1|ensembl:ENSP00000514011.1|ensembl:ENSP00000514012.1	psi-mi:ubia_yerpe(display_long)|uniprotkb:ubiA(gene name)|psi-mi:ubiA(display_short)|uniprotkb:4-HB polyprenyltransferase(gene name synonym)|uniprotkb:YPO0311(locus name)|uniprotkb:y0569(locus name)|uniprotkb:YP_0467(locus name)	psi-mi:il2rb_human(display_long)|uniprotkb:IL2RB(gene name)|psi-mi:IL2RB(display_short)|uniprotkb:High affinity IL-2 receptor subunit beta(gene name synonym)|uniprotkb:p70-75(gene name synonym)|uniprotkb:Interleukin-15 receptor subunit beta(gene name synonym)|uniprotkb:IL15RB(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866776|imex:IM-13779-7253	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006370(4-hydroxybenzoate polyprenyl transferase)|interpro:IPR000537(UbiA prenyltransferase)|interpro:IPR039653|interpro:IPR030470|refseq:WP_002209088.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0008412""(4-hydroxybenzoate polyprenyltransferase activity)|refseq:YP_002345392.1|interpro:IPR044878|panther:PTHR11048(orthology-group)"	"dip:DIP-43N|ensembl:ENSG00000100385.15(gene)|ensembl:ENST00000216223.10(transcript)|ensembl:ENST00000429622.6(transcript)|ensembl:ENST00000445595.2(transcript)|ensembl:ENST00000453962.6(transcript)|ensembl:ENST00000698883.1(transcript)|ensembl:ENST00000698890.1(transcript)|ensembl:ENST00000698892.1(transcript)|ensembl:ENST00000698893.1(transcript)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0004911""(interleukin-2 receptor activity)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005893""(interleukin-2 receptor complex)|go:""GO:0007165""(signal transduction)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019976""(interleukin-2 binding)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0042010""(interleukin-15 receptor activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040951|mint:P14784|rcsb pdb:2B5I|rcsb pdb:2ERJ|rcsb pdb:3QAZ|rcsb pdb:4GS7|rcsb pdb:5M5E|rcsb pdb:6E8K|rcsb pdb:7S2S|reactome:R-HSA-5673001|reactome:R-HSA-8983432|reactome:R-HSA-9020558|reactome:R-HSA-912526|refseq:NP_000869.1|refseq:NP_001333151.1|refseq:NP_001333152.1|efo:""Orphanet:85408""|efo:""Orphanet:85410""|panther:PTHR23037(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:GjFeBs/EfKbB2hBFbbdayn0OuqA632	rogid:fIx5nlom1q65wGMoXZ2SZl3Y4nc9606	intact-crc:7DB5E762D81F0F33|rigid:kbiASOF6jKLNs03YbzX2zphMQQo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P25963	uniprotkb:Q8ZH00	intact:EBI-307386|uniprotkb:B2R8L6|ensembl:ENSP00000216797.6	intact:EBI-2840229|uniprotkb:Q0WHT0	psi-mi:ikba_human(display_long)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	psi-mi:succ_yerpe(display_long)|uniprotkb:sucC(gene name)|psi-mi:sucC(display_short)|uniprotkb:Succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:YPO1115(locus name)|uniprotkb:y3065(locus name)|uniprotkb:YP_1041(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866809|imex:IM-13779-7259	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:150""|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:98813""|ensembl:ENSG00000100906.12(gene)|ensembl:ENST00000216797.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007253""(obsolete cytoplasmic sequestering of NF-kappaB)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0010745""(negative regulation of macrophage derived foam cell differentiation)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0045638""(negative regulation of myeloid cell differentiation)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070417""(cellular response to cold)|go:""GO:0070427""(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140313""(molecular sequestering activity)|go:""GO:0140416""(transcription regulator inhibitor activity)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR051070|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9692916|reactome:R-HSA-9860927|refseq:NP_065390.1|dip:DIP-139N|ensembl:ENSP00000216797.6|panther:PTHR46680(orthology-group)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR017866|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004775""(""succinate-CoA ligase (ADP-forming) activity"")|go:""GO:0004776""(""succinate-CoA ligase (GDP-forming) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006104""(succinyl-CoA metabolic process)|go:""GO:0042709""(succinate-CoA ligase complex)|refseq:WP_002210728.1|refseq:YP_002346158.1|panther:PTHR11815(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	rogid:1+/NEPeTCLwoXSGE7Uwddz1a7Kg632	intact-crc:1B81727A36B022AF|rigid:vUwO3VZFK/OVv5hTL1Bb5ckYcis	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01591	uniprotkb:A0A6B3VBG4	intact:EBI-2866826|ensembl:ENSP00000254801.4|ensembl:ENSP00000426687.1	intact:EBI-2852922	psi-mi:igj_human(display_long)|uniprotkb:JCHAIN(gene name)|psi-mi:JCHAIN(display_short)|uniprotkb:IGCJ(gene name synonym)|uniprotkb:IGJ(gene name synonym)|uniprotkb:Joining chain of multimeric IgA and IgM(gene name synonym)	psi-mi:a0a6b3vbg4_yerpe(display_long)|uniprotkb:y3441(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866823|imex:IM-13779-7257	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011530227.1|refseq:XP_011530228.1|refseq:NP_653247.1|refseq:XP_006714274.1|refseq:XP_006714275.1|ensembl:ENSG00000132465.12(gene)|ensembl:ENST00000254801.9(transcript)|ensembl:ENST00000510437.5(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019862""(IgA binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045087""(innate immune response)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071750""(dimeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR024110|mint:P01591|rcsb pdb:6KXS|rcsb pdb:6LX3|rcsb pdb:6LXW|rcsb pdb:6UE7|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|rcsb pdb:7K0C|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPE|rcsb pdb:8BPF|rcsb pdb:8GZN|rcsb pdb:8SKU|rcsb pdb:8SKV|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR10070(orthology-group)"	"interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR042187|uniprotkb:A0A6B3T508(uniprot-removed-ac)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009288""(bacterial-type flagellum)|refseq:WP_002223682.1|interpro:IPR046358"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0LaSqZzqBXZZZx+9zeTse0tZOdo9606	rogid:lSNXlJTIub0W1CW9Z3nGnfxHIa0632	intact-crc:D195CB6A0B5159EB|rigid:Ffn0+Y4UNtDsVHoxwkPCDtHF0/Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15111	uniprotkb:Q8D017	intact:EBI-81249|uniprotkb:O14666|uniprotkb:Q13132|uniprotkb:Q5W0I4|uniprotkb:Q92467|ensembl:ENSP00000359424.6|intact:EBI-28970970	intact:EBI-2840083|uniprotkb:Q74WG0	psi-mi:ikka_human(display_long)|uniprotkb:CHUK(gene name)|psi-mi:CHUK(display_short)|uniprotkb:IKKA(gene name synonym)|uniprotkb:TCF16(gene name synonym)|uniprotkb:I-kappa-B kinase 1(gene name synonym)|uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym)|uniprotkb:Transcription factor 16(gene name synonym)	psi-mi:q8d017_yerpe(display_long)|uniprotkb:tar1(gene name)|psi-mi:tar1(display_short)|uniprotkb:YP_0911(locus name)|uniprotkb:y2958(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866802|imex:IM-13779-7256	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000213341.11(gene)|ensembl:ENST00000370397.8(transcript)|go:""GO:0003009""(skeletal muscle contraction)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008384""(IkappaB kinase activity)|go:""GO:0008385""(IkappaB kinase complex)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009615""(response to virus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010034""(response to acetate)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0033194""(response to hydroperoxide)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0061847""(response to cholecystokinin)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098586""(cellular response to virus)|go:""GO:1990459""(transferrin receptor binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022007|interpro:IPR041185|interpro:IPR046375|interpro:IPR051180|mint:O15111|rcsb pdb:3BRT|rcsb pdb:5EBZ|rcsb pdb:5TQW|rcsb pdb:5TQX|rcsb pdb:5TQY|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-198323|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5674400|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9705671|reactome:R-HSA-975144|reactome:R-HSA-9758274|reactome:R-HSA-9833482|reactome:R-HSA-9860276|reactome:R-HSA-9860927|refseq:NP_001269.3|panther:PTHR22969(orthology-group)|efo:""Orphanet:465824""|dip:DIP-27526N"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR033479|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|interpro:IPR029151|interpro:IPR051310"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:FVB/gXjSBTB9hdq9pycQogxesms9606	rogid:i+QyWU6+baIyCTzI0P9uj/9+A7A632	intact-crc:E3FFD59609BDE16C|rigid:bLB+1/tsjS8Nt6CMATo3yhP3qbw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P25963	uniprotkb:Q8CZN4	intact:EBI-307386|uniprotkb:B2R8L6|ensembl:ENSP00000216797.6	intact:EBI-2862981	psi-mi:ikba_human(display_long)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	psi-mi:q8czn4_yerpe(display_long)|uniprotkb:y3760(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866816|imex:IM-13779-7258	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:150""|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:98813""|ensembl:ENSG00000100906.12(gene)|ensembl:ENST00000216797.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007253""(obsolete cytoplasmic sequestering of NF-kappaB)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0010745""(negative regulation of macrophage derived foam cell differentiation)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0010888""(negative regulation of lipid storage)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043330""(response to exogenous dsRNA)|go:""GO:0045638""(negative regulation of myeloid cell differentiation)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070417""(cellular response to cold)|go:""GO:0070427""(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140313""(molecular sequestering activity)|go:""GO:0140416""(transcription regulator inhibitor activity)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR051070|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9692916|reactome:R-HSA-9860927|refseq:NP_065390.1|dip:DIP-139N|ensembl:ENSP00000216797.6|panther:PTHR46680(orthology-group)"	"interpro:IPR032317|interpro:IPR006143(Secretion protein HlyD)|go:""GO:0009636""(response to toxic substance)|go:""GO:0016020""(membrane)|go:""GO:0022857""(transmembrane transporter activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	rogid:EiH5QICM0CrUOx+izcikVFr8gzY632	intact-crc:FB49619337D207EA|rigid:OuEOjWyZIg/mV0SzCt2LyZhl/1A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Z375	uniprotkb:Q13422	intact:EBI-2852829|uniprotkb:Q7CI43|uniprotkb:Q74UQ2|uniprotkb:A0A0H2W3B1|uniprotkb:A0A1U8QVE0|uniprotkb:A0A3N4B1F0	intact:EBI-745305|uniprotkb:O00598|uniprotkb:Q8WVA3|uniprotkb:Q53XL2|uniprotkb:B4E0Z1|uniprotkb:A4D260|uniprotkb:D3DVM5|uniprotkb:Q69BM4|intact:EBI-28969803|ensembl:ENSP00000331614.3	psi-mi:q9z375_yerpe(display_long)|uniprotkb:irp7(gene name)|psi-mi:irp7(display_short)|uniprotkb:ybtQ(gene name synonym)|uniprotkb:YPO1914(locus name)	psi-mi:ikzf1_human(display_long)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866795|imex:IM-13779-7255	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_002212761.1|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR036640|refseq:YP_002346905.1|interpro:IPR039421|panther:PTHR24222(orthology-group)"	"efo:""Orphanet:317473""|efo:""Orphanet:36426""|efo:""Orphanet:585909""|dip:DIP-41110N|ensembl:ENSG00000185811.21(gene)|ensembl:ENST00000331340.8(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007498""(mesoderm development)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030098""(lymphocyte differentiation)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050589|mint:Q13422|rcsb pdb:6H0F|rcsb pdb:8D7Z|rcsb pdb:8D80|rcsb pdb:8RQC|rcsb pdb:8TNP|rcsb pdb:8TNQ|rcsb pdb:8TNR|reactome:R-HSA-9013508|refseq:NP_001207694.1|refseq:NP_001207696.1|refseq:NP_001207697.1|refseq:NP_001207699.1|refseq:NP_001207700.1|refseq:NP_001278766.1|refseq:NP_001278767.1|refseq:NP_001278768.1|refseq:NP_001278769.1|refseq:NP_001278770.1|refseq:NP_001278771.1|refseq:NP_001278772.1|refseq:NP_001278773.1|refseq:NP_006051.1|refseq:XP_011513370.1|refseq:XP_011513371.1|refseq:XP_011513377.1|refseq:XP_011513378.1|refseq:XP_016867157.1|panther:PTHR24404(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:aJ6y5toJ2mfcSS+lal5tKlKh1Jk632	rogid:RizH0uz3DbSyFFvmlIhisx+S+DI9606	intact-crc:57B34C8ECC6A48F3|rigid:ZQfAoTjh+pcHCcxaVHKx8Y+8n7U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:Q8CWI4	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2841215	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:q8cwi4_yerpe(display_long)|uniprotkb:kbl(gene name)|psi-mi:kbl(display_short)|uniprotkb:Glycine acetyltransferase(gene name synonym)|uniprotkb:y0081(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866852|imex:IM-13779-7264	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"interpro:IPR011282(2-amino-3-ketobutyrate coenzyme A ligase)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0008890""(glycine C-acetyltransferase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0016874""(ligase activity)|go:""GO:0019518""(L-threonine catabolic process to glycine)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR050087"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:uETD2R/0GvIqPvz6yt39/YuJzJQ632	intact-crc:31DC7C850432827F|rigid:rGUp1laeQadk0i3Klh9/VwjcnFI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CK83	uniprotkb:P01857	intact:EBI-2851851|uniprotkb:Q74QS6	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	psi-mi:q8ck83_yerpe(display_long)|uniprotkb:accC1(gene name)|psi-mi:accC1(display_short)|uniprotkb:YP_3384(locus name)|uniprotkb:y4042(locus name)	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866866|imex:IM-13779-7262	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|go:""GO:0005524""(ATP binding)|go:""GO:0016874""(ligase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR052032"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:zWNetqBcgNgoffpGm1WuBpGKZiA632	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	intact-crc:28B4208505B6D49C|rigid:bJ9JQFePt7G5QAwBfvKKa1EyjkI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1J4	uniprotkb:P01857	intact:EBI-2866844|uniprotkb:Q74R57	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	psi-mi:q8d1j4_yerpe(display_long)|uniprotkb:YP_3226(locus name)|uniprotkb:y0408(locus name)	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866841|imex:IM-13779-7261	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003744(Protein of unknown function DUF165)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:1990397""(queuosine salvage)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:yTWGbd/rhZyBday/Xq0arCbmg70632	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	intact-crc:85EE08D20432718A|rigid:2ESTvCb9uLCtU1If8IQuGvYHSoI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:Q8CKN0	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2845390	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:q8ckn0_yerpe(display_long)|uniprotkb:y3261(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866859|imex:IM-13779-7263	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	interpro:IPR009241(Protein of unknown function DUF891)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:SE+YZBFvvwyvu5gamIwWEcVlxhs632	intact-crc:4FC220850540EF3D|rigid:Szr3eFw3EXiXT23982v/2PhYvtE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01591	uniprotkb:A0A5P8YE29	intact:EBI-2866826|ensembl:ENSP00000254801.4|ensembl:ENSP00000426687.1	intact:EBI-2843406|uniprotkb:Q0WHI7|uniprotkb:Q7CH97	psi-mi:igj_human(display_long)|uniprotkb:JCHAIN(gene name)|psi-mi:JCHAIN(display_short)|uniprotkb:IGCJ(gene name synonym)|uniprotkb:IGJ(gene name synonym)|uniprotkb:Joining chain of multimeric IgA and IgM(gene name synonym)	psi-mi:a0a5p8ye29_yerpe(display_long)|uniprotkb:rcsC(gene name)|psi-mi:rcsC(display_short)|uniprotkb:YPO1217(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866834|imex:IM-13779-7260	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011530227.1|refseq:XP_011530228.1|refseq:NP_653247.1|refseq:XP_006714274.1|refseq:XP_006714275.1|ensembl:ENSG00000132465.12(gene)|ensembl:ENST00000254801.9(transcript)|ensembl:ENST00000510437.5(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019862""(IgA binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045087""(innate immune response)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071750""(dimeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR024110|mint:P01591|rcsb pdb:6KXS|rcsb pdb:6LX3|rcsb pdb:6LXW|rcsb pdb:6UE7|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|rcsb pdb:7K0C|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPE|rcsb pdb:8BPF|rcsb pdb:8GZN|rcsb pdb:8SKU|rcsb pdb:8SKV|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR10070(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR019017|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR005467(Signal transduction histidine kinase, core)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR038388|interpro:IPR036097|interpro:IPR036890|interpro:IPR030856|refseq:YP_002346251.1|panther:PTHR43711(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0LaSqZzqBXZZZx+9zeTse0tZOdo9606	rogid:GIjut+P7rq0118T0f8OkgWIkre0632	intact-crc:46732D6AE6721227|rigid:56N3jN5R2e1/PO442M+L9ZKXB40	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YCS1	uniprotkb:P01877	intact:EBI-2845539|uniprotkb:Q74X99|uniprotkb:Q7CKL1|uniprotkb:A0A0H2W363	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	psi-mi:a0a5p8ycs1_yerpe(display_long)|uniprotkb:fklB(gene name)|psi-mi:fklB(display_short)|uniprotkb:YPO3532(locus name)	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866901|imex:IM-13779-7269	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR000774(Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal)|refseq:WP_002228198.1|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0006457""(protein folding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR036944|refseq:YP_002348421.1|interpro:IPR046357|panther:PTHR43811(orthology-group)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3Rld9RV594sVyXzqp5V7qbiNN1s632	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	intact-crc:2895AFDF9813FA5F|rigid:icUKP/buUJHwyPiF82e5SJrdqUI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01877	uniprotkb:A0A2U2H346	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	intact:EBI-2849136|uniprotkb:Q74TG8|uniprotkb:A0A0H2W5H4|uniprotkb:Q0WEC0|uniprotkb:Q7CIT1|uniprotkb:A0A384KWM5	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	psi-mi:a0a2u2h346_yerpe(display_long)|uniprotkb:YPO2403(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866908|imex:IM-13779-7267	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"interpro:IPR010231(SUF system FeS cluster assembly, SufB)|interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|refseq:WP_002211808.1|go:""GO:0016226""(iron-sulfur cluster assembly)|interpro:IPR037284|refseq:YP_002347368.1|interpro:IPR045595"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	rogid:DkCekEHB1T0D0zddmetEadbmVDk632	intact-crc:89E78C0BA66BCFBE|rigid:ejfaNLRJXbgRD3bulB2Nq9spu2g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:A0A384KHP8	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2840740|uniprotkb:Q74S58|uniprotkb:Q0WHX7|uniprotkb:Q7CH24	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:a0a384khp8_yerpe(display_long)|uniprotkb:cutF(gene name)|psi-mi:cutF(display_short)|uniprotkb:nlpE(gene name synonym)|uniprotkb:YPO1067(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866880|imex:IM-13779-7266	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	interpro:IPR007298(Copper resistance lipoprotein NlpE)|interpro:IPR033450|interpro:IPR038139|interpro:IPR043176|refseq:YP_002346111.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:ryLPtdXQoNwxiqxUzYaySoAkJkc632	intact-crc:2D65083441D9AAA4|rigid:WDvZPq/UqQUlBTr21Svh82hFA3M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:A0A2U2GVZ6	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2842971|uniprotkb:Q74W16|uniprotkb:A0A0H2W2X1|uniprotkb:Q7CJU6|uniprotkb:A0A3N4AZS9|uniprotkb:A0A384L7G7	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:a0a2u2gvz6_yerpe(display_long)|uniprotkb:ubiF(gene name)|psi-mi:ubiF(display_short)|uniprotkb:YPO2621(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866873|imex:IM-13779-7265	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR010971(Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6)|go:""GO:0004497""(monooxygenase activity)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0016705""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:""GO:0071949""(FAD binding)|refseq:WP_002210347.1|interpro:IPR036188|refseq:YP_002347577.1|interpro:IPR051205"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:zKOVHd4RmzcakJDi4rlK0Xy9yNc632	intact-crc:7735F6855D07F40A|rigid:2VrSftR3ofHTapkHHHxxupzrf9s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01877	uniprotkb:A0A3G5L2D0	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	intact:EBI-2865067	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	psi-mi:a0a3g5l2d0_yerpe(display_long)|uniprotkb:dgoA1(gene name)|psi-mi:dgoA1(display_short)|uniprotkb:mdlA(gene name synonym)|uniprotkb:NCTC5923_01545(orf name)|uniprotkb:YP_1455(locus name)|uniprotkb:y2598(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866894|imex:IM-13779-7268	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"uniprotkb:A0A5P8YE18(uniprot-removed-ac)|interpro:IPR013341(Mandelate racemase/muconate lactonizing enzyme, N-terminal)|interpro:IPR013342(Mandelate racemase/muconate lactonizing enzyme, C-terminal)|interpro:IPR018110|interpro:IPR029017|interpro:IPR029065|interpro:IPR034610|interpro:IPR036849|go:""GO:0009063""(amino acid catabolic process)|go:""GO:0016052""(carbohydrate catabolic process)|go:""GO:0016853""(isomerase activity)|go:""GO:0050023""(L-fuconate dehydratase activity)|refseq:WP_002211917.1|interpro:IPR046945"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	rogid:VVqXuBcpx8OVQX8Y9zSahq0fRvI632	intact-crc:2834AB660E64D248|rigid:WrotINdwPDAl1FD66CN2CTXhU9o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PFM0	uniprotkb:P01857	intact:EBI-2846871|uniprotkb:Q74QH1|uniprotkb:A0A0H2W7H4|uniprotkb:Q7CGR9|uniprotkb:A0A384LFS9	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	psi-mi:a0a2s9pfm0_yerpe(display_long)|uniprotkb:YPO0938(locus name)	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866887|imex:IM-13779-7270	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017755(N-carbamoylputrescine amidase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:WP_002209979.1|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0050126""(N-carbamoylputrescine amidase activity)|interpro:IPR036526|refseq:YP_002345985.1|interpro:IPR050345"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:VEt5ZICBEzJqD2dQaZCgWKgplSI632	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	intact-crc:A759915DEB736B07|rigid:qYV2vaRpf8RmaPVwiSX7rkMXEek	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01877	uniprotkb:A0A2S9PGH0	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	intact:EBI-2843672|uniprotkb:Q74VD9|uniprotkb:Q7CHN7|uniprotkb:A0A380SBG1|uniprotkb:Q0WGU1	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	psi-mi:a0a2s9pgh0_yerpe(display_long)|uniprotkb:YPO1482(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866922|imex:IM-13779-7272	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	interpro:IPR010623(Protein of unknown function DUF1215)|interpro:IPR009612(ImcF-related)|refseq:WP_002211936.1|interpro:IPR048677|refseq:YP_002346497.1|interpro:IPR053156	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	rogid:QiN5WQU27+ZNFJoP65QaVCbJABo632	intact-crc:0E2A322FBAF0F2C1|rigid:mKy9mKFgJ3ZYb4e5HJQZ6GzpHl4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YKP4	uniprotkb:P01877	intact:EBI-2853948|uniprotkb:Q74RP4|uniprotkb:Q7CGH3|uniprotkb:Q0WJ06	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	psi-mi:a0a5p8ykp4_yerpe(display_long)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:YPO0664(locus name)	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866943|imex:IM-13779-7273	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020084|interpro:IPR004385(Nucleoside diphosphate pyrophosphatase)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:WP_002212184.1|go:""GO:0005829""(cytosol)|go:""GO:0006753""(nucleoside phosphate metabolic process)|go:""GO:0019144""(ADP-sugar diphosphatase activity)|go:""GO:0019693""(ribose phosphate metabolic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_002345732.1|panther:PTHR11839(orthology-group)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ji/dszpJhw/6y6lx3coWs2NZfpY632	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	intact-crc:23CA2C377E9D93CE|rigid:7tV2B0p3qM75rzBicBVEQHl0h3I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PH42	uniprotkb:P01877	intact:EBI-2843976|uniprotkb:Q7CI41|uniprotkb:A0A3N4B635|uniprotkb:Q0WFN6	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	psi-mi:a0a2s9ph42_yerpe(display_long)|uniprotkb:irp2(gene name)|psi-mi:irp2(display_short)|uniprotkb:YPO1911(locus name)	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866915|imex:IM-13779-7271	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020806|rcsb pdb:7JTJ|rcsb pdb:7JUA|interpro:IPR029063|interpro:IPR010071(Amino acid adenylation)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001242(Condensation domain)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR020845|go:""GO:0003824""(catalytic activity)|go:""GO:0009403""(toxin biosynthetic process)|go:""GO:0031177""(phosphopantetheine binding)|refseq:WP_002212775.1|rcsb pdb:2N6Y|rcsb pdb:2N6Z|rcsb pdb:5U3H|interpro:IPR023213|interpro:IPR036736|rcsb pdb:7RY6|interpro:IPR042099|refseq:YP_002346902.1|interpro:IPR045851"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KfeTeZp+lut8Pzz4JrX7HMjjWS0632	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	intact-crc:F2F184CFC3F98230|rigid:9EyI5jdwheop/yJQ92eCe/2Syzc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A384KL32	uniprotkb:P01877	intact:EBI-2855180|uniprotkb:Q74WI8|uniprotkb:Q7CHC3|uniprotkb:Q0WHF1	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	psi-mi:a0a384kl32_yerpe(display_long)|uniprotkb:YPO1258(locus name)	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866936|imex:IM-13779-7274	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR052947|interpro:IPR016583(Uncharacterised conserved protein UCP011452, HNH endonuclease domain, YhhZ)|interpro:IPR003615(HNH nuclease)|refseq:WP_002208839.1|interpro:IPR044925|panther:PTHR34319(orthology-group)	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:k8VGxxWPx+NdmGLFn262erw8Wf8632	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	intact-crc:E7ACAF19BCE44058|rigid:Q4DbCGqoMRsy+TP1NJ+GFY/Km+k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01877	uniprotkb:Q7CGP7	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	intact:EBI-2843574|uniprotkb:Q74VF3|uniprotkb:Q7CHM9|uniprotkb:A0A3N4B420|uniprotkb:Q0WI64	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	psi-mi:q7cgp7_yerpe(display_long)|uniprotkb:YPO0977(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866929|imex:IM-13779-7275	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	refseq:WP_002215896.1|interpro:IPR010269(Protein of unknown function DUF877)|interpro:IPR044031|interpro:IPR044032|refseq:YP_002346024.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	rogid:A2hLeo982wqHfqZx1t4r2clSWXk632	intact-crc:5ED84E09D91D9DBC|rigid:p3XSlkEdrAtU+teAbd0sdGOpVhQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCP4	uniprotkb:P01877	intact:EBI-2859224|uniprotkb:Q0WCX8	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	psi-mi:pdxj_yerpe(display_long)|uniprotkb:pdxJ(gene name)|psi-mi:pdxJ(display_short)|uniprotkb:YPO2930(locus name)|uniprotkb:y1300(locus name)|uniprotkb:YP_2525(locus name)	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866950|imex:IM-13779-7276	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004569(""Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ"")|rcsb pdb:3F4N|refseq:WP_002211569.1|go:""GO:0005829""(cytosol)|go:""GO:0008615""(pyridoxine biosynthetic process)|go:""GO:0033856""(pyridoxine 5'-phosphate synthase activity)|interpro:IPR036130|refseq:YP_002347860.1|panther:PTHR30456(orthology-group)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:V3zZ7N7jjvgdZvAJZUyN3RJoUiQ632	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	intact-crc:4B66DF1906F89D43|rigid:pgHcZaCGMou4p9pTh+VVPwlVHjw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01877	uniprotkb:Q8Z9R8	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	intact:EBI-2839934|uniprotkb:Q0W9Q7|intact:EBI-2857683|intact:EBI-2870000	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	psi-mi:mnmg_yerpe(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:YPO4130(locus name)|uniprotkb:y4144(locus name)|uniprotkb:YP_4037(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866957|imex:IM-13779-7277	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|interpro:IPR044920|interpro:IPR026904|refseq:WP_002212259.1|interpro:IPR049312|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|interpro:IPR047001|refseq:YP_002348981.1|interpro:IPR040131|panther:PTHR11806(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	rogid:v90IkqKm+dlosxfAPKVYWCflBG4632	intact-crc:805EE519056C323D|rigid:/3+qMDXQ0jK7EPlyddpYXXMerH0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3V073	uniprotkb:P08069	intact:EBI-2848832	intact:EBI-475981|uniprotkb:Q14CV2|uniprotkb:B1B5Y2|uniprotkb:Q9UCC0|ensembl:ENSP00000497069.1	psi-mi:a0a6b3v073_yerpe(display_long)|uniprotkb:y0859(locus name)	psi-mi:igf1r_human(display_long)|uniprotkb:Insulin-like growth factor I receptor(gene name synonym)|uniprotkb:IGF1R(gene name)|psi-mi:IGF1R(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866964|imex:IM-13779-7280	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3SZJ3(uniprot-removed-ac)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR050107|refseq:WP_002223226.1"	"ensembl:ENSG00000140443.15(gene)|ensembl:ENST00000650285.1(transcript)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0003230""(cardiac atrium development)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005158""(insulin receptor binding)|go:""GO:0005520""(insulin-like growth factor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005899""(insulin receptor complex)|go:""GO:0005901""(caveola)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0007409""(axonogenesis)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008288""(boss receptor activity)|go:""GO:0010656""(negative regulation of muscle cell apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0021549""(cerebellum development)|go:""GO:0021766""(hippocampus development)|go:""GO:0030010""(establishment of cell polarity)|go:""GO:0030315""(T-tubule)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0031994""(insulin-like growth factor I binding)|go:""GO:0032467""(positive regulation of cytokinesis)|go:""GO:0033197""(response to vitamin E)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034224""(cellular response to zinc ion starvation)|go:""GO:0035094""(response to nicotine)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035867""(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043235""(receptor complex)|go:""GO:0043243""(positive regulation of protein-containing complex disassembly)|go:""GO:0043279""(response to alkaloid)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0043559""(insulin binding)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0044849""(estrous cycle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045056""(transcytosis)|go:""GO:0045471""(response to ethanol)|go:""GO:0046328""(regulation of JNK cascade)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0051054""(positive regulation of DNA metabolic process)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071393""(cellular response to progesterone stimulus)|go:""GO:0071394""(cellular response to testosterone stimulus)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090031""(positive regulation of steroid hormone biosynthetic process)|go:""GO:0090398""(cellular senescence)|go:""GO:0097062""(dendritic spine maintenance)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140318""(protein transporter activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1902065""(response to L-glutamate)|go:""GO:1902911""(protein kinase complex)|go:""GO:1903944""(negative regulation of hepatocyte apoptotic process)|go:""GO:1904045""(cellular response to aldosterone)|go:""GO:1904193""(negative regulation of cholangiocyte apoptotic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:1990314""(cellular response to insulin-like growth factor stimulus)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016246(Insulin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036941|interpro:IPR050122|mint:P08069|rcsb pdb:1IGR|rcsb pdb:1JQH|rcsb pdb:1K3A|rcsb pdb:1M7N|rcsb pdb:1P4O|rcsb pdb:2OJ9|rcsb pdb:2ZM3|rcsb pdb:3D94|rcsb pdb:3F5P|rcsb pdb:3I81|rcsb pdb:3LVP|rcsb pdb:3LW0|rcsb pdb:3NW5|rcsb pdb:3NW6|rcsb pdb:3NW7|rcsb pdb:3O23|rcsb pdb:3QQU|rcsb pdb:4D2R|rcsb pdb:4XSS|rcsb pdb:5FXQ|rcsb pdb:5FXR|rcsb pdb:5FXS|rcsb pdb:5HZN|rcsb pdb:5U8Q|rcsb pdb:5U8R|rcsb pdb:6JK8|rcsb pdb:6VWG|rcsb pdb:6VWH|rcsb pdb:6VWI|rcsb pdb:6VWJ|rcsb pdb:7PH8|rcsb pdb:7S0Q|rcsb pdb:7S8V|rcsb pdb:7U23|rcsb pdb:7V3P|rcsb pdb:7XGD|rcsb pdb:7XLC|rcsb pdb:7YRR|rcsb pdb:8PYI|rcsb pdb:8PYJ|rcsb pdb:8PYK|rcsb pdb:8PYL|rcsb pdb:8PYM|rcsb pdb:8PYN|rcsb pdb:8TAN|reactome:R-HSA-2404192|reactome:R-HSA-2428928|reactome:R-HSA-2428933|reactome:R-HSA-9009391|reactome:R-HSA-9820960|refseq:NP_000866.1|refseq:NP_001278787.1|dip:DIP-476N|efo:""Orphanet:73273""|panther:PTHR24416(orthology-group)|ensembl:ENSP00000497069.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:gbuCcuxKRXbgvu4tZlurt/LtiPs632	rogid:5RlIkDngFFJ/IO9tyZQnh1Riz0s9606	intact-crc:550CD89F502DD140|rigid:sRPMoZ9T8DuJfAb4aY6aUAtqD4I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D051	uniprotkb:P78318	intact:EBI-2856027	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784.4|ensembl:ENSP00000363661.5	psi-mi:q8d051_yerpe(display_long)|uniprotkb:y2759(locus name)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866978|imex:IM-13779-7278	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR050298|interpro:IPR001897(Porin, bacterial type)|interpro:IPR001702(Porin, Gram-negative type)|interpro:IPR013793(Porin, general diffusion Gram-negative, conserved site)|interpro:IPR033900|go:""GO:0009279""(cell outer membrane)|go:""GO:0015288""(porin activity)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0046930""(pore complex)|interpro:IPR023614"	"ensembl:ENSG00000089289.16(gene)|ensembl:ENST00000342206.10(transcript)|ensembl:ENST00000356413.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0032873""(negative regulation of stress-activated MAPK cascade)|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035303""(regulation of dephosphorylation)|go:""GO:0042113""(B cell activation)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0060632""(regulation of microtubule-based movement)|go:""GO:0070555""(response to interleukin-1)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|refseq:NP_001542.1|refseq:XP_016884978.1|efo:""Orphanet:52055""|panther:PTHR10933(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wY/QWrt/DKI3164kNHTGn3zhlx0632	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	intact-crc:7660882B1AD57878|rigid:ltwLVleb7nosMwAxMoXwi8MzFzg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZDF8	uniprotkb:P78318	intact:EBI-2843052|uniprotkb:Q0WDS2	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784.4|ensembl:ENSP00000363661.5	psi-mi:syl_yerpe(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO2610(locus name)|uniprotkb:YP_1103(locus name)|uniprotkb:y1184(locus name)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866971|imex:IM-13779-7279	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR025709|interpro:IPR015413(""Aminoacyl-tRNA synthetase, class I (M)"")|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004823""(leucine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006429""(leucyl-tRNA aminoacylation)|refseq:WP_002210333.1|refseq:YP_002347566.1|panther:PTHR43740(orthology-group)"	"ensembl:ENSG00000089289.16(gene)|ensembl:ENST00000342206.10(transcript)|ensembl:ENST00000356413.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0019888""(protein phosphatase regulator activity)|go:""GO:0032873""(negative regulation of stress-activated MAPK cascade)|go:""GO:0034612""(response to tumor necrosis factor)|go:""GO:0035303""(regulation of dephosphorylation)|go:""GO:0042113""(B cell activation)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0060632""(regulation of microtubule-based movement)|go:""GO:0070555""(response to interleukin-1)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|refseq:NP_001542.1|refseq:XP_016884978.1|efo:""Orphanet:52055""|panther:PTHR10933(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3sEWdGj2m6kDFCDXlrNdwz7rjRs632	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	intact-crc:AB34EF95187C7A67|rigid:orzXijvZdG1Iz8A4L+3J1qSqCYg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01629	uniprotkb:A0A5P8YIF2	intact:EBI-373124|uniprotkb:Q96DA8|uniprotkb:Q6FH82|ensembl:ENSP00000484689.1|ensembl:ENSP00000505840.1	intact:EBI-2866985	psi-mi:ifm2_human(display_long)|uniprotkb:IFITM2(gene name)|psi-mi:IFITM2(display_short)|uniprotkb:Interferon-inducible protein 1-8D(gene name synonym)|uniprotkb:Dispanin subfamily A member 2c(gene name synonym)	psi-mi:a0a5p8yif2_yerpe(display_long)|uniprotkb:yapA(gene name)|psi-mi:yapA(display_short)|uniprotkb:y1346(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866990|imex:IM-13779-7281	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENST00000616316.3(transcript)|refseq:NP_006426.2|ensembl:ENST00000680197.1(transcript)|ensembl:ENSG00000185201.18(gene)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009615""(response to virus)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|interpro:IPR051517|reactome:R-HSA-909733|panther:PTHR13999(orthology-group)"	"uniprotkb:Q8D0Z3(uniprot-removed-ac)|interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR030930|interpro:IPR036709|interpro:IPR051551|go:""GO:0019867""(outer membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tuhid+OEGpPbsGE2dFHG5owwbsE9606	rogid:KlFcJEuM0GDuY7337UP8lYRS3Wc632	intact-crc:C36AA1C711F922DD|rigid:kiKSRKQoozZp3AuhQ3IN6zv12nM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WJ32	uniprotkb:Q01629	intact:EBI-2867009|uniprotkb:Q74RR6|uniprotkb:A0A0H2W811|uniprotkb:Q7CGG3|uniprotkb:A0A384KV50|uniprotkb:A0A5P8YJF0	intact:EBI-373124|uniprotkb:Q96DA8|uniprotkb:Q6FH82|ensembl:ENSP00000484689.1|ensembl:ENSP00000505840.1	psi-mi:q0wj32_yerpe(display_long)|uniprotkb:YPO0639(locus name)	psi-mi:ifm2_human(display_long)|uniprotkb:IFITM2(gene name)|psi-mi:IFITM2(display_short)|uniprotkb:Interferon-inducible protein 1-8D(gene name synonym)|uniprotkb:Dispanin subfamily A member 2c(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867013|imex:IM-13779-7285	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR016583(Uncharacterised conserved protein UCP011452, HNH endonuclease domain, YhhZ)|interpro:IPR003615(HNH nuclease)|refseq:WP_002210362.1|interpro:IPR052947|interpro:IPR044925	"ensembl:ENST00000616316.3(transcript)|refseq:NP_006426.2|ensembl:ENST00000680197.1(transcript)|ensembl:ENSG00000185201.18(gene)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009615""(response to virus)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|interpro:IPR051517|reactome:R-HSA-909733|panther:PTHR13999(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9RR4inhJHJcCeRv6A/+vRYwa0LQ632	rogid:tuhid+OEGpPbsGE2dFHG5owwbsE9606	intact-crc:38D5D71C0E7E2630|rigid:aEsYfVQr1geSgzRctp13E3cLP74	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YDZ3	uniprotkb:Q01629	intact:EBI-2867000|uniprotkb:Q74QE9|uniprotkb:Q7CGX1|uniprotkb:Q0WIJ9	intact:EBI-373124|uniprotkb:Q96DA8|uniprotkb:Q6FH82|ensembl:ENSP00000484689.1|ensembl:ENSP00000505840.1	psi-mi:a0a5p8ydz3_yerpe(display_long)|uniprotkb:YPO0838(locus name)	psi-mi:ifm2_human(display_long)|uniprotkb:IFITM2(gene name)|psi-mi:IFITM2(display_short)|uniprotkb:Interferon-inducible protein 1-8D(gene name synonym)|uniprotkb:Dispanin subfamily A member 2c(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2866997|imex:IM-13779-7282	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR032466|interpro:IPR003764(N-acetylglucosamine-6-phosphate deacetylase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR006680(Amidohydrolase 1)|refseq:WP_002209882.1|go:""GO:0006046""(N-acetylglucosamine catabolic process)|go:""GO:0008448""(N-acetylglucosamine-6-phosphate deacetylase activity)|go:""GO:0046872""(metal ion binding)|refseq:YP_002345889.1|panther:PTHR11113(orthology-group)"	"ensembl:ENST00000616316.3(transcript)|refseq:NP_006426.2|ensembl:ENST00000680197.1(transcript)|ensembl:ENSG00000185201.18(gene)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009615""(response to virus)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|interpro:IPR051517|reactome:R-HSA-909733|panther:PTHR13999(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7GWjy6strlN9BEdSrMfb8xo9tB0632	rogid:tuhid+OEGpPbsGE2dFHG5owwbsE9606	intact-crc:770693BFD11E0807|rigid:xRLCLBlu4blOhPLXzW3I2pUAdUI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ZC41	uniprotkb:P13164	intact:EBI-2867023|uniprotkb:Q7CI54|uniprotkb:Q74UN6|uniprotkb:A0A384KWK4|uniprotkb:A0A1U8QMC4|uniprotkb:A0A0H2W5F0|uniprotkb:A0A2U2GZW1	intact:EBI-348505|uniprotkb:Q15322|ensembl:ENSP00000330825.5|ensembl:ENSP00000386187.3|ensembl:ENSP00000437057.1|ensembl:ENSP00000505380.1|uniprotkb:Q53XZ0	psi-mi:q9zc41_yerpe(display_long)|uniprotkb:YPO1931(locus name)	psi-mi:ifm1_human(display_long)|uniprotkb:IFITM1(gene name)|psi-mi:IFITM1(display_short)|uniprotkb:IFI17(gene name synonym)|uniprotkb:Interferon-inducible protein 9-27(gene name synonym)|uniprotkb:Interferon-induced protein 17(gene name synonym)|uniprotkb:Leu-13 antigen(gene name synonym)|uniprotkb:CD225(gene name synonym)|uniprotkb:Dispanin subfamily A member 2a(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867020|imex:IM-13779-7284	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002212065.1|refseq:YP_002346920.1	"refseq:NP_003632.3|ensembl:ENSG00000185885.17(gene)|ensembl:ENST00000328221.5(transcript)|ensembl:ENST00000408968.4(transcript)|ensembl:ENST00000528780.5(transcript)|ensembl:ENST00000680588.1(transcript)|go:""GO:0001503""(ossification)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|interpro:IPR051517|mint:P13164|reactome:R-HSA-198933|reactome:R-HSA-909733|dip:DIP-32672N|panther:PTHR13999(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Pvc7pK62d08XJDsR+kIFI+5jPQE632	rogid:+WojFAUu4AZAydvg1PBePvxrBWs9606	intact-crc:582E5B4295CC0245|rigid:Pv8+r2+kr5KeTIcekvxo/lURZUY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13164	uniprotkb:Q8D0N9	intact:EBI-348505|uniprotkb:Q15322|ensembl:ENSP00000330825.5|ensembl:ENSP00000386187.3|ensembl:ENSP00000437057.1|ensembl:ENSP00000505380.1|uniprotkb:Q53XZ0	intact:EBI-2845331|uniprotkb:Q74UJ0	psi-mi:ifm1_human(display_long)|uniprotkb:IFITM1(gene name)|psi-mi:IFITM1(display_short)|uniprotkb:IFI17(gene name synonym)|uniprotkb:Interferon-inducible protein 9-27(gene name synonym)|uniprotkb:Interferon-induced protein 17(gene name synonym)|uniprotkb:Leu-13 antigen(gene name synonym)|uniprotkb:CD225(gene name synonym)|uniprotkb:Dispanin subfamily A member 2a(gene name synonym)	psi-mi:q8d0n9_yerpe(display_long)|uniprotkb:pqiB2(gene name)|psi-mi:pqiB2(display_short)|uniprotkb:YP_1726(locus name)|uniprotkb:y1863(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867032|imex:IM-13779-7283	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003632.3|ensembl:ENSG00000185885.17(gene)|ensembl:ENST00000328221.5(transcript)|ensembl:ENST00000408968.4(transcript)|ensembl:ENST00000528780.5(transcript)|ensembl:ENST00000680588.1(transcript)|go:""GO:0001503""(ossification)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|interpro:IPR051517|mint:P13164|reactome:R-HSA-198933|reactome:R-HSA-909733|dip:DIP-32672N|panther:PTHR13999(orthology-group)"	"interpro:IPR003399(Mammalian cell entry related)|go:""GO:0016020""(membrane)|interpro:IPR051800"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+WojFAUu4AZAydvg1PBePvxrBWs9606	rogid:ubTQpOsKz5MxAzZCDHdFKkWSofo632	intact-crc:A0EDBB21E63B45B1|rigid:TWEm5vss1mUgZ6U7+9w5p6g0x34	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17778	uniprotkb:P40305	intact:EBI-2842665|uniprotkb:O68701	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867046|imex:IM-13779-7287	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	intact-crc:E1EAFDE6BD94C016|rigid:cdjyXYmN5TA0oqSzrHDq/bi4Is0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H4G8	uniprotkb:P40305	intact:EBI-2853974|uniprotkb:Q74QW2|uniprotkb:Q0WA39|uniprotkb:A0A5P8YAW1|uniprotkb:Q7CG08|uniprotkb:A0A384KLT9	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	psi-mi:a0a2u2h4g8_yerpe(display_long)|uniprotkb:YPO3979(locus name)	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867067|imex:IM-13779-7288	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003474(Gluconate transporter)|refseq:WP_002209536.1|go:""GO:0015128""(gluconate transmembrane transporter activity)|go:""GO:0016020""(membrane)|refseq:YP_002348849.1"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:II0t1Tc6ziV59KfG3br4G58qfsU632	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	intact-crc:87098D67998DB742|rigid:6MomduSh0Wq56f977pmrn1kUZ7Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14879	uniprotkb:Q8CZK5	intact:EBI-745127|uniprotkb:Q99634|uniprotkb:Q9BSK7|ensembl:ENSP00000360876.4|ensembl:ENSP00000360883.4|ensembl:ENSP00000505987.1	intact:EBI-2845872|uniprotkb:Q74QX9	psi-mi:ifit3_human(display_long)|uniprotkb:ISG-60(gene name synonym)|uniprotkb:CIG49(gene name synonym)|uniprotkb:Retinoic acid-induced gene G protein(gene name synonym)|uniprotkb:Interferon-induced protein with tetratricopeptide repeats 4(gene name synonym)|uniprotkb:Interferon-induced 60 kDa protein(gene name synonym)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:IFI60(gene name synonym)|uniprotkb:IFIT4(gene name synonym)|uniprotkb:CIG-49(gene name synonym)|uniprotkb:ISG60(gene name synonym)	psi-mi:q8czk5_yerpe(display_long)|uniprotkb:fba(gene name)|psi-mi:fba(display_short)|uniprotkb:YP_3323(locus name)|uniprotkb:y3869(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867039|imex:IM-13779-7286	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001026853.1|refseq:NP_001540.2|dip:DIP-37890N|ensembl:ENSG00000119917.15(gene)|ensembl:ENST00000371811.4(transcript)|ensembl:ENST00000371818.9(transcript)|ensembl:ENST00000679781.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009615""(response to virus)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0051607""(defense response to virus)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O14879|rcsb pdb:6C6K|reactome:R-HSA-909733|panther:PTHR10271(orthology-group)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000771(Ketose-bisphosphate aldolase, class-II)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016832""(aldehyde-lyase activity)|interpro:IPR050246"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606	rogid:F4QkMnJWZdUUOo6ENRO8BbcEL+I632	intact-crc:231A5E5066D7AFB0|rigid:mYv9j1gD7R+tTMEImMfVE/8I4do	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40305	uniprotkb:A0A3N4BEU0	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867053|imex:IM-13779-7290	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	intact-crc:3812B7E27C8590A8|rigid:2U9vpGlUMS+N84mIjRSvP1WYkfw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40305	uniprotkb:A0A0H2W496	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867060|imex:IM-13779-7289	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	intact-crc:D0122C07AFEE51EE|rigid:ijz+2XDqNGlz4lfwHBxkgE3wysM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHF1	uniprotkb:P40305	intact:EBI-2849437|uniprotkb:Q0WI93	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	psi-mi:glsa1_yerpe(display_long)|uniprotkb:glsA1(gene name)|psi-mi:glsA1(display_short)|uniprotkb:YPO0949(locus name)|uniprotkb:y3336(locus name)|uniprotkb:YP_3492(locus name)	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867081|imex:IM-13779-7292	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|refseq:WP_002209989.1|go:""GO:0004359""(glutaminase activity)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006543""(glutamine catabolic process)|refseq:YP_002345995.1|panther:PTHR12544(orthology-group)"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RXiLjz5WJJYlM97YSg1neu4h+FA632	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	intact-crc:2E01477D9B4C79E7|rigid:C3bBf+QWIqmKsj2vd8IV2JMrbmo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YEZ8	uniprotkb:Q15056	intact:EBI-2845602|uniprotkb:Q74U77|uniprotkb:Q0WFE2|uniprotkb:Q7CIA0|uniprotkb:A0A384LA14	intact:EBI-748492|uniprotkb:A8K3R1|uniprotkb:D3DXF6|uniprotkb:D3DXF8|ensembl:ENSP00000265753.8	psi-mi:a0a5p8yez8_yerpe(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:YPO2010(locus name)	psi-mi:if4h_human(display_long)|uniprotkb:Williams-Beuren syndrome chromosomal region 1 protein(gene name synonym)|uniprotkb:EIF4H(gene name)|psi-mi:EIF4H(display_short)|uniprotkb:WBSCR1(gene name synonym)|uniprotkb:KIAA0038(gene name synonym)|uniprotkb:WSCR1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867095|imex:IM-13779-7294	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|interpro:IPR004095(TGS)|interpro:IPR031167|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0043023""(ribosomal large subunit binding)|interpro:IPR041706|refseq:WP_002211245.1|refseq:YP_002346996.1|panther:PTHR23305(orthology-group)"	"ensembl:ENSG00000106682.16(gene)|ensembl:ENST00000265753.13(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016020""(membrane)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0019953""(sexual reproduction)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048589""(developmental growth)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034229|interpro:IPR035979|mint:Q15056|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_071496.1|refseq:NP_114381.1|efo:""Orphanet:904""|panther:PTHR23236(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3iq6UNiclH9s/Tvlmo7cFMlj60w632	rogid:dNPoAzwFD5lFwCMnRl0cbXM3j8s9606	intact-crc:7C1C97CFDC7E3D57|rigid:Q6HovAHKtU9Qw2BOpW4BvtLYJKM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P55010	uniprotkb:Q8D097	intact:EBI-286450|uniprotkb:Q9H5N2|uniprotkb:Q9UG48|uniprotkb:Q53XB3|ensembl:ENSP00000216554.3|ensembl:ENSP00000376477.2|ensembl:ENSP00000453743.1	intact:EBI-2849686	psi-mi:if5_human(display_long)|uniprotkb:EIF5(gene name)|psi-mi:EIF5(display_short)	psi-mi:q8d097_yerpe(display_long)|uniprotkb:ptrB(gene name)|psi-mi:ptrB(display_short)|uniprotkb:y2527(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867088|imex:IM-13779-7295	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001960.2|refseq:NP_892116.2|ensembl:ENSG00000100664.11(gene)|ensembl:ENST00000216554.8(transcript)|ensembl:ENST00000392715.6(transcript)|ensembl:ENST00000558506.1(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005092""(GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0042255""(ribosome assembly)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0071074""(eukaryotic initiation factor eIF2 binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|interpro:IPR045196|mint:P55010|rcsb pdb:2E9H|rcsb pdb:2G2K|rcsb pdb:2IU1|rcsb pdb:8OZ0|rcsb pdb:8PJ2|rcsb pdb:8PJ3|reactome:R-HSA-72702|reactome:R-HSA-72706|panther:PTHR23001(orthology-group)"	"interpro:IPR023302|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002470(Peptidase S9A, prolyl oligopeptidase)|interpro:IPR029058|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:WP_002231190.1|interpro:IPR051543"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/07	rogid:lM5AZJWJOQGbxADfl8MGCx3JAXc9606	rogid:e1PUtAFibeLqTuVlv0AfdoPCzZQ632	intact-crc:0A429EE5863E1D03|rigid:3xnjlm+5USagYM3APYK6ZOOZIBs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40305	uniprotkb:Q8ZG09	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	intact:EBI-2842762|uniprotkb:Q74VB1|uniprotkb:Q7CHQ5|uniprotkb:Q0WGR1	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	psi-mi:mao1_yerpe(display_long)|uniprotkb:maeA(gene name)|psi-mi:maeA(display_short)|uniprotkb:YPO1511(locus name)|uniprotkb:y2658(locus name)|uniprotkb:YP_1401(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867074|imex:IM-13779-7291	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR001891(Malic oxidoreductase)|interpro:IPR023667|go:""GO:0004470""(malic enzyme activity)|go:""GO:0004471""(""malate dehydrogenase (decarboxylating) (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006108""(malate metabolic process)|go:""GO:0008948""(oxaloacetate decarboxylase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051287""(NAD binding)|refseq:WP_002211968.1|interpro:IPR036291|interpro:IPR037062|refseq:YP_002346527.1|interpro:IPR046346|panther:PTHR23406(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	rogid:3qTE5pPHB/ePJ+WGe7JGTqu1xJA632	intact-crc:568E987D99B8BB77|rigid:otlz63sQiPwpJACFx06KpEsaFAs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1F5	uniprotkb:O43432	intact:EBI-2855341|uniprotkb:Q74XG8	intact:EBI-464766|uniprotkb:Q5SWC3|uniprotkb:Q15597|uniprotkb:Q8NEN1|uniprotkb:Q504Z1|uniprotkb:B9EGQ7|ensembl:ENSP00000264211.7	psi-mi:q8d1f5_yerpe(display_long)|uniprotkb:terD(gene name)|psi-mi:terD(display_short)|uniprotkb:YP_0456(locus name)|uniprotkb:y0559(locus name)	psi-mi:if4g3_human(display_long)|uniprotkb:EIF4G3(gene name)|psi-mi:EIF4G3(display_short)|uniprotkb:eIF-4-gamma II(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867102|imex:IM-13779-7293	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051324|interpro:IPR003325(Bacterial stress protein)|go:""GO:0046690""(response to tellurium ion)"	"refseq:NP_001185732.1|refseq:NP_003751.2|refseq:NP_001185731.1|refseq:NP_001185730.1|panther:PTHR23253(orthology-group)|ensembl:ENSG00000075151.24(gene)|ensembl:ENST00000264211.13(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0007286""(spermatid development)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0045727""(positive regulation of translation)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016024(Armadillo-type fold)|mint:O43432|rcsb pdb:1HU3|reactome:R-HSA-1169408|refseq:XP_016858189.1|refseq:XP_016858197.1|refseq:XP_016858201.1|dip:DIP-33245N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GID0fZFhER54eVQ645Wu5Y80Fxo632	rogid:dN5046U5kz1WfBJD0+NWYMMU6RY9606	intact-crc:6FA83A652CC1ADF8|rigid:+XsN0nOxNKlqCUgzrnmdW33bMEI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D052	uniprotkb:P23588	intact:EBI-2844272	intact:EBI-970310|ensembl:ENSP00000262056.9|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13	psi-mi:q8d052_yerpe(display_long)|uniprotkb:uup(gene name)|psi-mi:uup(display_short)|uniprotkb:y2750(locus name)	psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867134|imex:IM-13779-7299	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR032781|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006281""(DNA repair)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0043022""(ribosome binding)|interpro:IPR032524|interpro:IPR037118|interpro:IPR043686|interpro:IPR051309"	"ensembl:ENSG00000063046.18(gene)|ensembl:ENST00000262056.14(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865|refseq:NP_001408.2|refseq:NP_001317583.1|panther:PTHR23236(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ewwtV+JDkE77jP90pjuqGPJnH48632	rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606	intact-crc:B53A20CCBC7982D5|rigid:ydIgkXjLE4d0V+EdVa76iMkRFUk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0W1	uniprotkb:O43432	intact:EBI-2841250|uniprotkb:Q74SK3	intact:EBI-464766|uniprotkb:Q5SWC3|uniprotkb:Q15597|uniprotkb:Q8NEN1|uniprotkb:Q504Z1|uniprotkb:B9EGQ7|ensembl:ENSP00000264211.7	psi-mi:q8d0w1_yerpe(display_long)|uniprotkb:csgG(gene name)|psi-mi:csgG(display_short)|uniprotkb:YP_2597(locus name)|uniprotkb:y1512(locus name)	psi-mi:if4g3_human(display_long)|uniprotkb:EIF4G3(gene name)|psi-mi:EIF4G3(display_short)|uniprotkb:eIF-4-gamma II(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867109|imex:IM-13779-7296	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005534(Curli production assembly/transport component CsgG)|go:""GO:0005886""(plasma membrane)|go:""GO:0030288""(outer membrane-bounded periplasmic space)"	"refseq:NP_001185732.1|refseq:NP_003751.2|refseq:NP_001185731.1|refseq:NP_001185730.1|panther:PTHR23253(orthology-group)|ensembl:ENSG00000075151.24(gene)|ensembl:ENST00000264211.13(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0007286""(spermatid development)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0045727""(positive regulation of translation)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016024(Armadillo-type fold)|mint:O43432|rcsb pdb:1HU3|reactome:R-HSA-1169408|refseq:XP_016858189.1|refseq:XP_016858197.1|refseq:XP_016858201.1|dip:DIP-33245N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zwYB9F8vJ7Vkr8em8p8HTA+eROA632	rogid:dN5046U5kz1WfBJD0+NWYMMU6RY9606	intact-crc:C1144B652DB7C349|rigid:ateKBYnMamjPrrJFfqSVFCSqWeg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GUX9	uniprotkb:P38919	intact:EBI-2841416|uniprotkb:A0A0H2W940|uniprotkb:Q74PB0|uniprotkb:A0A384LLI5|uniprotkb:Q7CFN3|uniprotkb:A0A3N4BJ32	intact:EBI-299104|uniprotkb:Q15033|uniprotkb:Q96A18|uniprotkb:Q6IBQ2|ensembl:ENSP00000497641.1|ensembl:ENSP00000497661.1|ensembl:ENSP00000516984.1|ensembl:ENSP00000516985.1|intact:EBI-21354615	psi-mi:a0a2u2gux9_yerpe(display_long)|uniprotkb:YPO4108(locus name)	psi-mi:if4a3_human(display_long)|uniprotkb:KIAA0111(gene name synonym)|uniprotkb:EIF4A3(gene name)|psi-mi:EIF4A3(display_short)|uniprotkb:DDX48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym)|uniprotkb:Eukaryotic initiation factor 4A-like NUK-34(gene name synonym)|uniprotkb:Nuclear matrix protein 265(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867141|imex:IM-13779-7298	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR041492|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002215575.1|refseq:YP_002348959.1|interpro:IPR023198|interpro:IPR036412|interpro:IPR051600"	"ensembl:ENSG00000141543.12(gene)|ensembl:ENSG00000291508.1(gene)|ensembl:ENST00000647795.1(transcript)|ensembl:ENST00000649764.2(transcript)|ensembl:ENST00000707787.1(transcript)|ensembl:ENST00000707791.1(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006364""(rRNA processing)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008306""(associative learning)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030425""(dendrite)|go:""GO:0035145""(exon-exon junction complex)|go:""GO:0035368""(selenocysteine insertion sequence binding)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0035640""(exploration behavior)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0048701""(embryonic cranial skeleton morphogenesis)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071006""(U2-type catalytic step 1 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0072715""(cellular response to selenite ion)|go:""GO:0090394""(negative regulation of excitatory postsynaptic potential)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099578""(regulation of translation at postsynapse, modulating synaptic transmission)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1904570""(negative regulation of selenocysteine incorporation)|go:""GO:1990416""(cellular response to brain-derived neurotrophic factor stimulus)|go:""GO:2000622""(regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P38919|rcsb pdb:2HXY|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2J0U|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:7A5P|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:7ZNJ|rcsb pdb:8C6J|rcsb pdb:8I0W|rcsb pdb:9FMD|reactome:R-HSA-1169408|reactome:R-HSA-159236|reactome:R-HSA-429947|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|reactome:R-HSA-9820841|reactome:R-HSA-9820865|refseq:NP_055555.1|efo:""Orphanet:3102""|dip:DIP-33218N|panther:PTHR47958(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/27	rogid:N4DmZVhdbeJX1EvnC462dwFiaNU632	rogid:8e6e4HlM1GsYqqgXyJ9XgzxLzls9606	intact-crc:FD7B2D233A5DCB1A|rigid:kS8whsAGSANsseR7ldH9aKwRi6M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZC49	uniprotkb:O60573	intact:EBI-2852010|uniprotkb:Q0WCB0	intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416.3	psi-mi:thii_yerpe(display_long)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:YPO3173(locus name)|uniprotkb:y1012(locus name)|uniprotkb:YP_0758(locus name)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym)	psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867127|imex:IM-13779-7300	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026340|interpro:IPR001763(Rhodanese-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|refseq:WP_002208658.1|go:""GO:0000049""(tRNA binding)|go:""GO:0002937""(tRNA 4-thiouridine biosynthesis)|go:""GO:0004810""(CCA tRNA nucleotidyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0052837""(thiazole biosynthetic process)|go:""GO:0140741""(tRNA-uracil-4 sulfurtransferase activity)|interpro:IPR036873|interpro:IPR054173|refseq:YP_002348078.1|interpro:IPR049961|interpro:IPR049962|interpro:IPR050102|panther:PTHR43209(orthology-group)"	"refseq:NP_004837.1|ensembl:ENSG00000135930.15(gene)|ensembl:ENST00000258416.8(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0098808""(mRNA cap binding)|interpro:IPR001040(""Eukaryotic translation initiation factor 4E (eIF-4E)"")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|dip:DIP-32578N|refseq:NP_001263265.1|panther:PTHR11960(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/30	rogid:JVdYYtaSxHT0xyr6zYDRPl2jCF4632	rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606	intact-crc:72F4BAF672FEC3C5|rigid:KJ73KMplSEM90s1CzLAZfkYxziQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N5X7	uniprotkb:Q0WIW7	intact:EBI-2678645|uniprotkb:B2R963|uniprotkb:Q6NUT1|ensembl:ENSP00000393324.2	intact:EBI-2867116|uniprotkb:A0A0H2W7T3|uniprotkb:Q7CGJ8|uniprotkb:A0A384KXS0|uniprotkb:A0A5P8YJ50	psi-mi:if4e3_human(display_long)|uniprotkb:EIF4E3(gene name)|psi-mi:EIF4E3(display_short)	psi-mi:q0wiw7_yerpe(display_long)|uniprotkb:fliP(gene name)|psi-mi:fliP(display_short)|uniprotkb:YPO0709(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867120|imex:IM-13779-7297	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269815.1|refseq:NP_001128121.1|refseq:NP_001128122.1|refseq:NP_001128123.1|refseq:NP_775495.1|refseq:XP_016861767.1|refseq:XP_016861768.1|refseq:XP_016861769.1|refseq:XP_016861770.1|refseq:XP_016861771.1|ensembl:ENSG00000163412.13(gene)|ensembl:ENST00000425534.8(transcript)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|interpro:IPR001040(""Eukaryotic translation initiation factor 4E (eIF-4E)"")|interpro:IPR023398|mint:Q8N5X7|reactome:R-HSA-1169408|panther:PTHR11960(orthology-group)"	"interpro:IPR005837(Flagellar transport protein FliP)|interpro:IPR005838(Type III secretion system inner membrane P protein)|refseq:WP_002211448.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0044781""(bacterial-type flagellum organization)|refseq:YP_002345771.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:brJ17A04qwLckkJHjMd8d8DKsr89606	rogid:iDTK0yaSYvNQVK/+a3JtjmOEka0632	intact-crc:403DC21F970E91E5|rigid:rVVFEKu+6GY0BQ76kR2K+4Junwk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WDE1	uniprotkb:Q14240	intact:EBI-2848934|uniprotkb:Q74SY9|uniprotkb:Q8D0U7	intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381.5	psi-mi:prmb_yerpe(display_long)|uniprotkb:prmB(gene name)|psi-mi:prmB(display_short)|uniprotkb:N5-glutamine methyltransferase PrmB(gene name synonym)|uniprotkb:YPO2750(locus name)|uniprotkb:YP_2413(locus name)|uniprotkb:y1584(locus name)	psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867148|imex:IM-13779-7301	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029063|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004556(Modification methylase HemK)|interpro:IPR017127(""Protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific"")|interpro:IPR007848(Methyltransferase small)|refseq:WP_002209710.1|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005829""(cytosol)|go:""GO:0032259""(methylation)|go:""GO:0036009""(protein-glutamine N-methyltransferase activity)|refseq:YP_002347697.1|panther:PTHR47806(orthology-group)"	"panther:PTHR24031(orthology-group)|efo:""Orphanet:528084""|ensembl:ENSG00000156976.17(gene)|ensembl:ENST00000323963.10(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1900260""(negative regulation of RNA-dependent RNA polymerase activity)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865|refseq:NP_001958.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/30	rogid:E0TcJR1cPqw7XzHhfs/tgH45UN8632	rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606	intact-crc:7925AA5788478857|rigid:RGLg/KqC3TaNOEg5ihPZMw4OxCg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VBG4	uniprotkb:Q14240	intact:EBI-2852922	intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381.5	psi-mi:a0a6b3vbg4_yerpe(display_long)|uniprotkb:y3441(locus name)	psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867155|imex:IM-13779-7302	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR042187|uniprotkb:A0A6B3T508(uniprot-removed-ac)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009288""(bacterial-type flagellum)|refseq:WP_002223682.1|interpro:IPR046358"	"panther:PTHR24031(orthology-group)|efo:""Orphanet:528084""|ensembl:ENSG00000156976.17(gene)|ensembl:ENST00000323963.10(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1900260""(negative regulation of RNA-dependent RNA polymerase activity)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865|refseq:NP_001958.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/30	rogid:lSNXlJTIub0W1CW9Z3nGnfxHIa0632	rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606	intact-crc:3B469CCD25A120F1|rigid:hVAz0I07E0AgVRB4zZXXmUz0k8w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CJ96	uniprotkb:Q9Y6M1	intact:EBI-2850596|uniprotkb:Q74T19	intact:EBI-1024419|intact:EBI-1237206|intact:EBI-1059063|uniprotkb:A0A4Z0|uniprotkb:B3FTN2|uniprotkb:B3FTN3|uniprotkb:B3FTN4|ensembl:ENSP00000371634.3	psi-mi:pta_yerpe(display_long)|uniprotkb:YPO2567(locus name)|uniprotkb:YP_2378(locus name)|uniprotkb:y1620(locus name)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)	psi-mi:if2b2_human(display_long)|uniprotkb:IGF-II mRNA-binding protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma autoantigen p62(gene name synonym)|uniprotkb:VICKZ family member 2(gene name synonym)|uniprotkb:IGF2BP2(gene name)|psi-mi:IGF2BP2(display_short)|uniprotkb:IMP2(gene name synonym)|uniprotkb:VICKZ2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867176|imex:IM-13779-7303	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016475(Phosphate acetyltransferase, bacteria)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR010766(DRTGG)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|interpro:IPR028979|interpro:IPR027417|go:""GO:0005737""(cytoplasm)|go:""GO:0006085""(acetyl-CoA biosynthetic process)|go:""GO:0008959""(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113|refseq:YP_002347528.1|interpro:IPR050500|panther:PTHR43356(orthology-group)"	"refseq:NP_001278801.1|refseq:NP_001278802.1|refseq:NP_001278803.1|refseq:NP_001278804.1|refseq:NP_001007226.1|refseq:NP_006539.3|dip:DIP-35539N|ensembl:ENSG00000073792.16(gene)|ensembl:ENST00000382199.7(transcript)|go:""GO:0000932""(P-body)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0007399""(nervous system development)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0043489""(RNA stabilization)|go:""GO:0045182""(translation regulator activity)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0051028""(mRNA transport)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:1990247""(N6-methyladenosine-containing RNA reader activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034843|interpro:IPR035979|interpro:IPR036612|mint:Q9Y6M1|rcsb pdb:2CQH|rcsb pdb:6ROL|rcsb pdb:7Q98|rcsb pdb:7Q99|reactome:R-HSA-428359|panther:PTHR10288(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/19	rogid:bqj0y9j0HCwwtdNgPqUC52yFXB4632	rogid:k45UViReMAxCv2cu7+tx+auevQc9606	intact-crc:E0BAE130B3699F89|rigid:YBKQ9Ul9Qe5MK+yfMH8Vvc2yQvs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P60842	uniprotkb:A0A0H2W7E2	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831.8	intact:EBI-2848155|uniprotkb:A0A2U2H0T1|uniprotkb:Q74QL8|uniprotkb:Q0WI49|uniprotkb:Q7CGN6|uniprotkb:A0A384KKB9	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:a0a0h2w7e2_yerpe(display_long)|uniprotkb:iutA(gene name)|psi-mi:iutA(display_short)|uniprotkb:YPO0994(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867169|imex:IM-13779-7304	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001407.1|panther:PTHR24031(orthology-group)|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960.16(gene)|ensembl:ENST00000293831.13(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097165""(nuclear stress granule)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|rcsb pdb:7PPZ|rcsb pdb:7PQ0|rcsb pdb:8HUJ|rcsb pdb:8OZ0|rcsb pdb:8XXN|rcsb pdb:9AVR|rcsb pdb:9BLN|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010917(TonB-dependent receptor, conserved site)|refseq:WP_002211646.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002346039.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	rogid:h+zziPxtFmhqRng+3zCsRqmsI/M632	intact-crc:B03CF7B4CF5F0D46|rigid:7Z0Qp35JubK3blFVARJUch4qY1E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6M0NII6	uniprotkb:P60842	intact:EBI-2841704	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831.8	psi-mi:a0a6m0nii6_yerpe(display_long)|uniprotkb:y2471(locus name)	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867162|imex:IM-13779-7305	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T0M9(uniprot-removed-ac)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR029016|go:""GO:0007165""(signal transduction)|go:""GO:0016020""(membrane)|refseq:WP_002228541.1"	"refseq:NP_001407.1|panther:PTHR24031(orthology-group)|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960.16(gene)|ensembl:ENST00000293831.13(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097165""(nuclear stress granule)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|rcsb pdb:7PPZ|rcsb pdb:7PQ0|rcsb pdb:8HUJ|rcsb pdb:8OZ0|rcsb pdb:8XXN|rcsb pdb:9AVR|rcsb pdb:9BLN|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:d/mBSOpThH3MO4/Ze3GAgpPOK+o632	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	intact-crc:C1F8949755357C59|rigid:wIT1cJzMhYXXbqiU6WJEUcrKA80	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WIM0	uniprotkb:Q16666	intact:EBI-2867211|uniprotkb:Q74S16|uniprotkb:A0A0H2W6J2|uniprotkb:Q7CGY5|uniprotkb:A0A384LJW8	intact:EBI-2867186|uniprotkb:Q9UH78|uniprotkb:Q96AJ5|uniprotkb:Q5T3W7|uniprotkb:Q5T3X2|uniprotkb:Q5T3W8|uniprotkb:Q5T3X0|uniprotkb:Q8NEQ7|uniprotkb:Q8N9E5|uniprotkb:Q5T3X1|uniprotkb:Q59GX0|uniprotkb:B4DJT8|uniprotkb:H3BLV7|ensembl:ENSP00000295809.7|uniprotkb:A0A346JEQ3	psi-mi:q0wim0_yerpe(display_long)|uniprotkb:YPO0813(locus name)	psi-mi:if16_human(display_long)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867216|imex:IM-13779-7308	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000983(Bacterial general secretion pathway protein G)|interpro:IPR012902(Prepilin-type cleavage/methylation, N-terminal)|interpro:IPR013545(Type II secretion system protein G)|interpro:IPR010054(General secretion pathway protein G)|refseq:WP_002209862.1|interpro:IPR050470|go:""GO:0005886""(plasma membrane)|go:""GO:0015627""(type II protein secretion system complex)|go:""GO:0015628""(protein secretion by the type II secretion system)|refseq:YP_002345868.1|interpro:IPR045584|panther:PTHR30093(orthology-group)"	"refseq:NP_001193496.1|refseq:NP_005522.2|dip:DIP-42868N|ensembl:ENSG00000163565.20(gene)|ensembl:ENST00000295809.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001819""(positive regulation of cytokine production)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0006954""(inflammatory response)|go:""GO:0008134""(transcription factor binding)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051607""(defense response to virus)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0140972""(negative regulation of AIM2 inflammasome complex assembly)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040205|mint:Q16666|rcsb pdb:2OQ0|rcsb pdb:3B6Y|rcsb pdb:3RLN|rcsb pdb:3RLO|rcsb pdb:3RNU|rcsb pdb:4QGU|rcsb pdb:8X70|reactome:R-HSA-1834941|reactome:R-HSA-3270619|panther:PTHR12200(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jM5DlQXh5ZnroEj7es9EZuS7Kz0632	rogid:lZOhepRgcTRzXg7sDjJ44MWzbbY9606	intact-crc:43D6F8222834F669|rigid:58DB8IJrLSLPFy78U/XQb24UB6M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16666	uniprotkb:Q8ZED8	intact:EBI-2867186|uniprotkb:Q9UH78|uniprotkb:Q96AJ5|uniprotkb:Q5T3W7|uniprotkb:Q5T3X2|uniprotkb:Q5T3W8|uniprotkb:Q5T3X0|uniprotkb:Q8NEQ7|uniprotkb:Q8N9E5|uniprotkb:Q5T3X1|uniprotkb:Q59GX0|uniprotkb:B4DJT8|uniprotkb:H3BLV7|ensembl:ENSP00000295809.7|uniprotkb:A0A346JEQ3	intact:EBI-2840186|uniprotkb:Q0WET1	psi-mi:if16_human(display_long)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym)	psi-mi:rnb_yerpe(display_long)|uniprotkb:rnb(gene name)|psi-mi:rnb(display_short)|uniprotkb:Exoribonuclease II(gene name synonym)|uniprotkb:YPO2235(locus name)|uniprotkb:y2077(locus name)|uniprotkb:YP_2034(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867183|imex:IM-13779-7306	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193496.1|refseq:NP_005522.2|dip:DIP-42868N|ensembl:ENSG00000163565.20(gene)|ensembl:ENST00000295809.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001819""(positive regulation of cytokine production)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0006954""(inflammatory response)|go:""GO:0008134""(transcription factor binding)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051607""(defense response to virus)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0140972""(negative regulation of AIM2 inflammasome complex assembly)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040205|mint:Q16666|rcsb pdb:2OQ0|rcsb pdb:3B6Y|rcsb pdb:3RLN|rcsb pdb:3RLO|rcsb pdb:3RNU|rcsb pdb:4QGU|rcsb pdb:8X70|reactome:R-HSA-1834941|reactome:R-HSA-3270619|panther:PTHR12200(orthology-group)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR022966|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011804(Ribonuclease II, bacterial)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008859""(exoribonuclease II activity)|refseq:WP_002210605.1|interpro:IPR001900(Ribonuclease II and R)|refseq:YP_002347207.1|interpro:IPR050180|panther:PTHR23355(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lZOhepRgcTRzXg7sDjJ44MWzbbY9606	rogid:8bPsungEsr2YreZsZg9IgHPm9uI632	intact-crc:D24271F4A2D1B531|rigid:LfcdrSv9sOzMpFimn5oyjSdW+zI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16666	uniprotkb:Q7ARD3	intact:EBI-2867186|uniprotkb:Q9UH78|uniprotkb:Q96AJ5|uniprotkb:Q5T3W7|uniprotkb:Q5T3X2|uniprotkb:Q5T3W8|uniprotkb:Q5T3X0|uniprotkb:Q8NEQ7|uniprotkb:Q8N9E5|uniprotkb:Q5T3X1|uniprotkb:Q59GX0|uniprotkb:B4DJT8|uniprotkb:H3BLV7|ensembl:ENSP00000295809.7|uniprotkb:A0A346JEQ3	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:if16_human(display_long)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867223|imex:IM-13779-7307	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193496.1|refseq:NP_005522.2|dip:DIP-42868N|ensembl:ENSG00000163565.20(gene)|ensembl:ENST00000295809.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001819""(positive regulation of cytokine production)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0006954""(inflammatory response)|go:""GO:0008134""(transcription factor binding)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051607""(defense response to virus)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0140972""(negative regulation of AIM2 inflammasome complex assembly)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040205|mint:Q16666|rcsb pdb:2OQ0|rcsb pdb:3B6Y|rcsb pdb:3RLN|rcsb pdb:3RLO|rcsb pdb:3RNU|rcsb pdb:4QGU|rcsb pdb:8X70|reactome:R-HSA-1834941|reactome:R-HSA-3270619|panther:PTHR12200(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lZOhepRgcTRzXg7sDjJ44MWzbbY9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:7AEDD9067FD34B2F|rigid:g7rE+gTD9cexOLpvkytHr/cmCo8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16666	uniprotkb:Q8CZW4	intact:EBI-2867186|uniprotkb:Q9UH78|uniprotkb:Q96AJ5|uniprotkb:Q5T3W7|uniprotkb:Q5T3X2|uniprotkb:Q5T3W8|uniprotkb:Q5T3X0|uniprotkb:Q8NEQ7|uniprotkb:Q8N9E5|uniprotkb:Q5T3X1|uniprotkb:Q59GX0|uniprotkb:B4DJT8|uniprotkb:H3BLV7|ensembl:ENSP00000295809.7|uniprotkb:A0A346JEQ3	intact:EBI-2851384|uniprotkb:Q74QA0	psi-mi:if16_human(display_long)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym)	psi-mi:q8czw4_yerpe(display_long)|uniprotkb:y3277(locus name)|uniprotkb:fldB(gene name)|psi-mi:fldB(display_short)|uniprotkb:YP_3589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867204|imex:IM-13779-7309	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193496.1|refseq:NP_005522.2|dip:DIP-42868N|ensembl:ENSG00000163565.20(gene)|ensembl:ENST00000295809.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001819""(positive regulation of cytokine production)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0006954""(inflammatory response)|go:""GO:0008134""(transcription factor binding)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051607""(defense response to virus)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0140972""(negative regulation of AIM2 inflammasome complex assembly)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040205|mint:Q16666|rcsb pdb:2OQ0|rcsb pdb:3B6Y|rcsb pdb:3RLN|rcsb pdb:3RLO|rcsb pdb:3RNU|rcsb pdb:4QGU|rcsb pdb:8X70|reactome:R-HSA-1834941|reactome:R-HSA-3270619|panther:PTHR12200(orthology-group)"	"interpro:IPR029039|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001226(Flavodoxin, conserved site)|interpro:IPR010086(Flavodoxin, long chain)|go:""GO:0009055""(electron transfer activity)|go:""GO:0010181""(FMN binding)|interpro:IPR050619"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lZOhepRgcTRzXg7sDjJ44MWzbbY9606	rogid:FZlCLDczSf2Gjm4UsIPSSoGJH6E632	intact-crc:70B45F1DA1409F50|rigid:k9cIh8aVOJVSBgkKnNYAm+9v1pQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PIA6	uniprotkb:P32942	intact:EBI-2842908|uniprotkb:Q74VK3|uniprotkb:Q7CHE2|uniprotkb:A0A5P8YDR0|uniprotkb:A0A0H2W4I9	intact:EBI-725421|uniprotkb:Q6PD68|ensembl:ENSP00000160262.3	psi-mi:a0a2s9pia6_yerpe(display_long)|uniprotkb:YPO1289(locus name)	psi-mi:icam3_human(display_long)|uniprotkb:ICAM-R(gene name synonym)|uniprotkb:CDw50(gene name synonym)|uniprotkb:ICAM3(gene name)|psi-mi:ICAM3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867251|imex:IM-13779-7313	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011234(Fumarylacetoacetase, C-terminal-related)|refseq:WP_002208808.1|go:""GO:0003824""(catalytic activity)|go:""GO:0044281""(small molecule metabolic process)|interpro:IPR036663|refseq:YP_002346315.1|interpro:IPR051121"	"refseq:NP_002153.2|ensembl:ENSG00000076662.11(gene)|ensembl:ENST00000160262.10(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006909""(phagocytosis)|go:""GO:0007155""(cell adhesion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR003988(Intercellular adhesion molecule)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013768(Intercellular adhesion molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR047012|interpro:IPR048679|mint:P32942|rcsb pdb:1T0P|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-5621575|panther:PTHR13771(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3/IrNkmiHMcBViQNlB32br606NM632	rogid:8A5P9CHbmUsJmlUUbJACHW9Dg9k9606	intact-crc:F0F0C8C1B5DCBA4B|rigid:eDFXNyziXzRHz8pchXa49RJubvA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13598	uniprotkb:A0A380PE22	intact:EBI-2806056|uniprotkb:Q14600|ensembl:ENSP00000388666.1|ensembl:ENSP00000392634.2|ensembl:ENSP00000415283.1|ensembl:ENSP00000462579.1|ensembl:ENSP00000464665.1	intact:EBI-2856011|uniprotkb:A0A0H2W318|uniprotkb:Q74VW4|uniprotkb:Q7CJX4|uniprotkb:A0A384LD58	psi-mi:icam2_human(display_long)|uniprotkb:ICAM2(gene name)|psi-mi:ICAM2(display_short)	psi-mi:a0a380pe22_yerpe(display_long)|uniprotkb:YPO2801(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867258|imex:IM-13779-7312	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000864.2|refseq:NP_001093256.1|refseq:NP_001093257.1|refseq:NP_001093258.1|refseq:NP_001093259.1|ensembl:ENSG00000108622.11(gene)|ensembl:ENST00000412356.5(transcript)|ensembl:ENST00000418105.5(transcript)|ensembl:ENST00000449662.6(transcript)|ensembl:ENST00000579687.5(transcript)|ensembl:ENST00000579788.6(transcript)|go:""GO:0001931""(uropod)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0007155""(cell adhesion)|go:""GO:0016020""(membrane)|go:""GO:0032154""(cleavage furrow)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR003988(Intercellular adhesion molecule)|interpro:IPR013768(Intercellular adhesion molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR047012|mint:P13598|rcsb pdb:1ZXQ|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-5621575|panther:PTHR13771(orthology-group)"	interpro:IPR018677|refseq:WP_002209756.1|interpro:IPR025513|refseq:YP_002347742.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:46FxUe9wv2WIelobimN/4k+qSS89606	rogid:dGYO2y8tXuDYlpLIte+D054U4jc632	intact-crc:22F2A2F746B43476|rigid:6+KOlHI0f84P7zpcpcA9Xb9VwHY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W174	uniprotkb:Q02535	intact:EBI-2857409|uniprotkb:Q74WU9|uniprotkb:A0A3N4BLR1|uniprotkb:Q7CK49|uniprotkb:Q0WC84	intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689.5|ensembl:ENSP00000489102.1	psi-mi:a0a0h2w174_yerpe(display_long)|uniprotkb:malZ(gene name)|psi-mi:malZ(display_short)|uniprotkb:YPO3200(locus name)	psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867237|imex:IM-13779-7311	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004185(Glycoside hydrolase, family 13, N-terminal Ig-like region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017069(Maltodextrin glucosidase)|refseq:WP_002208678.1|go:""GO:0004558""(alpha-1,4-glucosidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:YP_002348104.1"	"refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318.9(gene)|ensembl:ENSG00000283060.2(gene)|ensembl:ENST00000374561.6(transcript)|ensembl:ENST00000634790.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001656""(metanephros development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0007417""(central nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0007517""(muscle organ development)|go:""GO:0007623""(circadian rhythm)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0030903""(notochord development)|go:""GO:0042476""(odontogenesis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0072750""(cellular response to leptomycin B)|go:""GO:0140416""(transcription regulator inhibitor activity)|go:""GO:1901707""(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|mint:Q02535|rcsb pdb:2LFH|reactome:R-HSA-9031628|panther:PTHR11723(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xXWAIuIiT4Lo4aYGy1vcRouNeV4632	rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606	intact-crc:4BC15682DA24083C|rigid:o6cDhHBcNIUTSXw0ecogAfcWKyc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4AWI2	uniprotkb:Q5TEJ8	intact:EBI-2850800|uniprotkb:Q74PQ4|uniprotkb:Q0WB69|uniprotkb:Q7CL85|uniprotkb:A0A384LA61	intact:EBI-2806032|uniprotkb:B4DZT9|uniprotkb:Q9NS90|uniprotkb:Q9BYB6|uniprotkb:Q5TEJ1|uniprotkb:Q68DP4|uniprotkb:A2RTZ3|uniprotkb:Q5TEJ9|uniprotkb:O60560|uniprotkb:Q5TEK1|uniprotkb:B4DZY3|ensembl:ENSP00000363031.3	psi-mi:a0a3n4awi2_yerpe(display_long)|uniprotkb:ntrA(gene name synonym)|uniprotkb:rpoN(gene name synonym)|uniprotkb:YPO3582(locus name)|uniprotkb:glnF(gene name)|psi-mi:glnF(display_short)	psi-mi:thms2_human(display_long)|uniprotkb:C1orf38(gene name synonym)|uniprotkb:ICB1(gene name synonym)|uniprotkb:Induced by contact to basement membrane 1 protein(gene name synonym)|uniprotkb:Thymocyte-expressed molecule involved in selection protein 2(gene name synonym)|uniprotkb:THEMIS2(gene name)|psi-mi:THEMIS2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867244|imex:IM-13779-7314	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000394(RNA polymerase sigma factor 54)|interpro:IPR007046(RNA polymerase sigma factor 54, core-binding)|interpro:IPR007634(RNA polymerase sigma factor 54, DNA-binding)|refseq:WP_002210115.1|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001216""(DNA-binding transcription activator activity)|go:""GO:0003677""(DNA binding)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0016987""(sigma factor activity)|interpro:IPR038709|refseq:YP_002348469.1|panther:PTHR32248(orthology-group)"	"refseq:NP_001273042.1|refseq:NP_001273044.1|refseq:NP_001034566.1|refseq:NP_001099026.1|refseq:NP_004839.2|ensembl:ENSG00000130775.16(gene)|ensembl:ENST00000373921.8(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050864""(regulation of B cell activation)|interpro:IPR025946|interpro:IPR039671|refseq:XP_006711113.1|panther:PTHR15215(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zdzEhy+OLn0kaYS9XKuSOj5MMBM632	rogid:d3p6WXby4vsV/5OIxCObzfSkoE89606	intact-crc:9BF2232A85DCDD43|rigid:AnPpY1Ua6Bupyc40UxeFh3bFmxQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75874	uniprotkb:Q7CHU1	intact:EBI-715695|uniprotkb:Q567U4|uniprotkb:Q6FHQ6|uniprotkb:Q7Z3V0|uniprotkb:Q93090|uniprotkb:Q9NTJ9|uniprotkb:Q9UKW8|ensembl:ENSP00000260985.2|ensembl:ENSP00000390265.1|ensembl:ENSP00000410513.1	intact:EBI-2841165|uniprotkb:Q74V60	"psi-mi:idhc_human(display_long)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:""NADP(+)-specific ICDH""(gene name synonym)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:PICD(gene name synonym)|uniprotkb:IDPc(gene name synonym)"	psi-mi:mtfa_yerpe(display_long)|uniprotkb:mtfA(gene name)|psi-mi:mtfA(display_short)|uniprotkb:Probable zinc metallopeptidase MtfA(gene name synonym)|uniprotkb:YPO1732(locus name)|uniprotkb:YP_1472(locus name)|uniprotkb:y2576(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2867230|imex:IM-13779-7310	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-59311N|ensembl:ENSG00000138413.14(gene)|ensembl:ENST00000345146.7(transcript)|ensembl:ENST00000415913.5(transcript)|ensembl:ENST00000446179.5(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004450""(""isocitrate dehydrogenase (NADP+) activity"")|rcsb pdb:1T0L|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005777""(peroxisome)|go:""GO:0005782""(peroxisomal matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006097""(glyoxylate cycle)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006102""(isocitrate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0006739""(NADP metabolic process)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0008585""(female gonad development)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|go:""GO:0060696""(regulation of phospholipid catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071071""(regulation of phospholipid biosynthetic process)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:O75874|rcsb pdb:1T09|rcsb pdb:3INM|rcsb pdb:3MAP|rcsb pdb:3MAR|rcsb pdb:3MAS|rcsb pdb:4I3K|rcsb pdb:4I3L|rcsb pdb:4KZO|rcsb pdb:4L03|rcsb pdb:4L04|rcsb pdb:4L06|rcsb pdb:4UMX|rcsb pdb:4UMY|rcsb pdb:4XRX|rcsb pdb:4XS3|rcsb pdb:5DE1|rcsb pdb:5GIR|rcsb pdb:5K10|rcsb pdb:5K11|rcsb pdb:5L57|rcsb pdb:5L58|rcsb pdb:5LGE|rcsb pdb:5SUN|rcsb pdb:5SVF|rcsb pdb:5TQH|rcsb pdb:5YFM|rcsb pdb:5YFN|rcsb pdb:6ADG|rcsb pdb:6B0Z|rcsb pdb:6BKX|rcsb pdb:6BKY|rcsb pdb:6BKZ|rcsb pdb:6BL0|rcsb pdb:6BL1|rcsb pdb:6BL2|rcsb pdb:6IO0|rcsb pdb:6O2Y|rcsb pdb:6O2Z|rcsb pdb:6PAY|rcsb pdb:6Q6F|rcsb pdb:6U4J|rcsb pdb:6VEI|rcsb pdb:6VG0|rcsb pdb:7PJM|rcsb pdb:7PJN|rcsb pdb:8BAY|rcsb pdb:8HB9|rcsb pdb:8T7D|rcsb pdb:8T7N|rcsb pdb:8T7O|rcsb pdb:8VH9|rcsb pdb:8VHA|rcsb pdb:8VHB|rcsb pdb:8VHC|rcsb pdb:8VHD|rcsb pdb:8VHE|reactome:R-HSA-2978092|reactome:R-HSA-389542|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9818025|refseq:NP_001269315.1|refseq:NP_001269316.1|refseq:NP_005887.2|efo:""Orphanet:163634""|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:296""|efo:""Orphanet:86845""|efo:""Orphanet:99646""|panther:PTHR11822(orthology-group)|ensembl:ENSP00000260985.2|ensembl:ENSP00000390265.1|ensembl:ENSP00000410513.1"	"refseq:YP_002346732.1|interpro:IPR024079|interpro:IPR010384(Protein of unknown function DUF980)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|refseq:WP_002211042.1|interpro:IPR042252|panther:PTHR30164(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:RFBziMEb70PKCzUCJm2jd40y44M9606	rogid:3PKDmcLXdDD+p8B4M6novftNc7A632	intact-crc:21231A28711A9572|rigid:Sv+LBlm0dy76zX6syZgRe60rwcw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81R83	uniprotkb:P06748	intact:EBI-2810574|uniprotkb:Q6KTE5|uniprotkb:Q6HZF6	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930.5|ensembl:ENSP00000428755.1	psi-mi:y2173_bacan(display_long)|uniprotkb:BA_2173(locus name)|uniprotkb:GBAA_2173(locus name)|uniprotkb:BAS2019(locus name)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828593|imex:IM-13779-3208	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009474(Protein of unknown function DUF1094)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_000063712.1|refseq:NP_844566.1|refseq:YP_028282.1"	"efo:""Orphanet:1775""|efo:""Orphanet:300865""|efo:""Orphanet:402026""|efo:""Orphanet:520""|efo:""Orphanet:98833""|efo:""Orphanet:98834""|efo:""Orphanet:98842""|panther:PTHR22747(orthology-group)|dip:DIP-30932N|ensembl:ENSP00000296930.5|ensembl:ENST00000351986.10|ensembl:ENSP00000341168.6|ensembl:ENST00000393820.2|ensembl:ENSP00000377408.2|ensembl:ENSP00000428755.1|ensembl:ENST00000678280.1|ensembl:ENSP00000503235.1|ensembl:ENSG00000181163.14(gene)|ensembl:ENST00000296930.10(transcript)|ensembl:ENST00000517671.5(transcript)|go:""GO:0000055""(ribosomal large subunit export from nucleus)|go:""GO:0000056""(ribosomal small subunit export from nucleus)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001652""(granular component)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006281""(DNA repair)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006913""(nucleocytoplasmic transport)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0010826""(negative regulation of centrosome duplication)|go:""GO:0016020""(membrane)|go:""GO:0019843""(rRNA binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030225""(macrophage differentiation)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032071""(regulation of endodeoxyribonuclease activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042255""(ribosome assembly)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043023""(ribosomal large subunit binding)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044387""(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046599""(regulation of centriole replication)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060699""(regulation of endoribonuclease activity)|go:""GO:0060735""(regulation of eIF2 alpha phosphorylation by dsRNA)|go:""GO:0090398""(cellular senescence)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1902629""(regulation of mRNA stability involved in cellular response to UV)|go:""GO:1902751""(positive regulation of cell cycle G2/M phase transition)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|rcsb pdb:7OBG|rcsb pdb:7OBH|rcsb pdb:8AH2|rcsb pdb:8AS5|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496|reactome:R-HSA-9692914|reactome:R-HSA-9700645|reactome:R-HSA-9725370|reactome:R-HSA-9725371|reactome:R-HSA-9833482|refseq:NP_001032827.1|refseq:NP_002511.1|refseq:NP_954654.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DwG1RQbAdj088ZOY9O74UrEBXms1392	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:AB59252797BBA25D|rigid:afeR+EJqIR8uIQRromySyyHKl8Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NWR9	uniprotkb:P61916	intact:EBI-2817669|uniprotkb:Q6KVV6|uniprotkb:E9QUG2|uniprotkb:Q81TT5|uniprotkb:A0A1Q4M2X2|uniprotkb:A0A0J1I2K7	intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|ensembl:ENSP00000451112.2|uniprotkb:B4DQV7	psi-mi:a0a6l8nwr9_bacan(display_long)|uniprotkb:GBAA_1175(locus name)	psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828613|imex:IM-13779-3216	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR025549|refseq:WP_000531418.1	"ensembl:ENSG00000119655.11(gene)|ensembl:ENST00000555619.6(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0009615""(response to virus)|go:""GO:0010467""(gene expression)|go:""GO:0010878""(cholesterol storage)|go:""GO:0015485""(cholesterol binding)|go:""GO:0015914""(phospholipid transport)|go:""GO:0019747""(regulation of isoprenoid metabolic process)|go:""GO:0019899""(enzyme binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0032366""(intracellular sterol transport)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0033344""(cholesterol efflux)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0046836""(glycolipid transport)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120020""(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038|refseq:NP_006423.1|efo:""Orphanet:216972""|efo:""Orphanet:216975""|efo:""Orphanet:216978""|efo:""Orphanet:216981""|efo:""Orphanet:216986""|panther:PTHR11306(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:juQx+w28efr5lPP/qoBvLnqcEmE1392	rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606	intact-crc:A978DB5329F1AEE8|rigid:77z5jS4/jy24CPsAp+0jbbendvc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HK67	uniprotkb:P55209	intact:EBI-2815211|uniprotkb:Q6KS75|uniprotkb:Q6HY61|uniprotkb:E9QQN8|uniprotkb:E9QQN9|uniprotkb:Q81PZ1|uniprotkb:A0A0F7RDJ0	intact:EBI-356392|uniprotkb:B3KNT8|ensembl:ENSP00000376947.3|ensembl:ENSP00000477538.1|uniprotkb:B3KV44|intact:EBI-21355522	psi-mi:a0a6l7hk67_bacan(display_long)|uniprotkb:GBAA_2648(locus name)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828648|imex:IM-13779-3212	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005543(PASTA)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR050515|go:""GO:0005886""(plasma membrane)|go:""GO:0008658""(penicillin binding)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|refseq:WP_000549348.1|interpro:IPR036138"	"refseq:NP_004528.1|refseq:NP_631946.1|ensembl:ENSG00000187109.15(gene)|ensembl:ENST00000393263.7(transcript)|ensembl:ENST00000618691.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0042393""(histone binding)|go:""GO:0042470""(melanosome)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0140713""(histone chaperone activity)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|interpro:IPR002164(""Nucleosome assembly protein (NAP)"")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|rcsb pdb:7UN3|rcsb pdb:7UN6|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|panther:PTHR11875(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ebZgkIx4kdtUxCYHTTIW/f29OTU1392	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	intact-crc:ACB856200C0BB795|rigid:nzPWaJqj/yIQvZFWjlaK8OFf7Vk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60500	uniprotkb:Q81X78	intact:EBI-996920|uniprotkb:A6NDH2|uniprotkb:C3RX61|ensembl:ENSP00000368190.4	intact:EBI-2819829|uniprotkb:Q6HR14|uniprotkb:Q6KKD3	psi-mi:nphn_human(display_long)|uniprotkb:Renal glomerulus-specific cell adhesion receptor(gene name synonym)|uniprotkb:NPHS1(gene name)|psi-mi:NPHS1(display_short)|uniprotkb:NPHN(gene name synonym)	psi-mi:eno_bacan(display_long)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:BA_5364(locus name)|uniprotkb:GBAA_5364(locus name)|uniprotkb:BAS4985(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828620|imex:IM-13779-3215	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:656""|efo:""Orphanet:839""|dip:DIP-36424N|ensembl:ENSG00000161270.20(gene)|ensembl:ENST00000378910.10(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007254""(JNK cascade)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007520""(myoblast fusion)|go:""GO:0010467""(gene expression)|go:""GO:0017022""(myosin binding)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0032836""(glomerular basement membrane development)|go:""GO:0035418""(protein localization to synapse)|go:""GO:0036057""(slit diaphragm)|go:""GO:0036060""(slit diaphragm assembly)|go:""GO:0042995""(cell projection)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072015""(podocyte development)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR051275|rcsb pdb:4ZRT|reactome:R-HSA-373753|refseq:NP_004637.1|panther:PTHR11640(orthology-group)"	"interpro:IPR000941(Enolase)|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|interpro:IPR029017|go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006096""(glycolytic process)|go:""GO:0009986""(cell surface)|refseq:WP_000103949.1|interpro:IPR036849|refseq:NP_847538.1|refseq:YP_031224.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wpKW+UMkkOjtVsmUNUG4X+M9s8U9606	rogid:CKEt3RHm3qCHHHvrHx0aadVESFk1392	intact-crc:A63FFFE585A49341|rigid:fDoDCljUcmv/ZhJfgFbmq/YSwbQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HG24	uniprotkb:P55209	intact:EBI-2811385|uniprotkb:Q6KMQ6|uniprotkb:Q6HTG4|uniprotkb:E9R169|uniprotkb:E9R170|uniprotkb:Q81M11|uniprotkb:A0A0F7R8D9	intact:EBI-356392|uniprotkb:B3KNT8|ensembl:ENSP00000376947.3|ensembl:ENSP00000477538.1|uniprotkb:B3KV44|intact:EBI-21355522	psi-mi:a0a6l7hg24_bacan(display_long)|uniprotkb:GBAA_4444(locus name)	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828634|imex:IM-13779-3213	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR051782|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000891288.1"	"refseq:NP_004528.1|refseq:NP_631946.1|ensembl:ENSG00000187109.15(gene)|ensembl:ENST00000393263.7(transcript)|ensembl:ENST00000618691.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0042393""(histone binding)|go:""GO:0042470""(melanosome)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0140713""(histone chaperone activity)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|interpro:IPR002164(""Nucleosome assembly protein (NAP)"")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|rcsb pdb:7UN3|rcsb pdb:7UN6|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|panther:PTHR11875(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/pw+ThQWZ4LMdrZ7n9sAVSfc+v41392	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	intact-crc:8BE62FD2D598C29D|rigid:mXjL8VLi5RROyzNjnAccXIzgmm0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P55209	uniprotkb:A0A6L7H5N1	intact:EBI-356392|uniprotkb:B3KNT8|ensembl:ENSP00000376947.3|ensembl:ENSP00000477538.1|uniprotkb:B3KV44|intact:EBI-21355522	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828641|imex:IM-13779-3214	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004528.1|refseq:NP_631946.1|ensembl:ENSG00000187109.15(gene)|ensembl:ENST00000393263.7(transcript)|ensembl:ENST00000618691.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0042393""(histone binding)|go:""GO:0042470""(melanosome)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0140713""(histone chaperone activity)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|interpro:IPR002164(""Nucleosome assembly protein (NAP)"")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|rcsb pdb:7UN3|rcsb pdb:7UN6|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|panther:PTHR11875(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:943838722D17852C|rigid:E+xcy2eQEZTwGmARpaBRwj5pWDc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P55209	uniprotkb:A0A6L8PE10	intact:EBI-356392|uniprotkb:B3KNT8|ensembl:ENSP00000376947.3|ensembl:ENSP00000477538.1|uniprotkb:B3KV44|intact:EBI-21355522	intact:EBI-2818555|uniprotkb:Q6KTZ8|uniprotkb:Q6I019|uniprotkb:E9R2B8|uniprotkb:E9R2B9|uniprotkb:Q81RU2|uniprotkb:A0A0F7RJ75	psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym)	psi-mi:a0a6l8pe10_bacan(display_long)|uniprotkb:GBAA_1945(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828627|imex:IM-13779-3217	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004528.1|refseq:NP_631946.1|ensembl:ENSG00000187109.15(gene)|ensembl:ENST00000393263.7(transcript)|ensembl:ENST00000618691.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0042393""(histone binding)|go:""GO:0042470""(melanosome)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0140713""(histone chaperone activity)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|interpro:IPR002164(""Nucleosome assembly protein (NAP)"")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|rcsb pdb:7UN3|rcsb pdb:7UN6|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1|panther:PTHR11875(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR014216(""ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD"")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR039421|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034040""(ATPase-coupled lipid transmembrane transporter activity)|go:""GO:0042883""(cysteine transport)|go:""GO:0140359""(ABC-type transporter activity)|refseq:WP_000824065.1|interpro:IPR036640"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606	rogid:7XCFAONaGDISWIyfy6ZvZMJ+Gh81392	intact-crc:0C3F8927B565AB77|rigid:Gb/YS0jahTCfnVyygk4uQGhXWVU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PQR9	uniprotkb:Q9UM47	intact:EBI-2828672|uniprotkb:Q6I3J2|uniprotkb:Q6KXA6|uniprotkb:E9R9P3|uniprotkb:E9R9P4|uniprotkb:Q81VA6|uniprotkb:A0A1S0QNX7|uniprotkb:A0A2P0H9W5	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388.1	psi-mi:a0a6l8pqr9_bacan(display_long)|uniprotkb:ald1(gene name)|psi-mi:ald1(display_short)|uniprotkb:GBAA_0592(locus name)	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828669|imex:IM-13779-3222	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR008141(Alanine dehydrogenase and pyridine nucleotide transhydrogenase)|go:""GO:0000166""(nucleotide binding)|go:""GO:0000286""(alanine dehydrogenase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0042853""(L-alanine catabolic process)|refseq:WP_001219742.1|interpro:IPR036291"	"efo:""Orphanet:136""|efo:""Orphanet:2591""|efo:""Orphanet:2789""|ensembl:ENSG00000074181.9(gene)|ensembl:ENST00000263388.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0009986""(cell surface)|go:""GO:0014016""(neuroblast differentiation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030900""(forebrain development)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048663""(neuron fate commitment)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0072104""(glomerular capillary formation)|go:""GO:1902895""(positive regulation of miRNA transcription)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|rcsb pdb:6XSW|rcsb pdb:8OS0|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802|refseq:NP_000426.2|dip:DIP-39827N|panther:PTHR45836(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:JNB2CBvULTGgpHCcdZ5+UAYw+PY1392	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	intact-crc:3FEF96C88EB09806|rigid:lsNCB0Qg7ECmUtrBswUUIrVk9ZA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HA16	uniprotkb:Q9UM47	intact:EBI-2814138|uniprotkb:Q6HQ53|uniprotkb:Q6F078|uniprotkb:E9RDY5|uniprotkb:E9RDY6|uniprotkb:Q81JL0|uniprotkb:A0A0F7R8Z5	intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388.1	psi-mi:a0a6l7ha16_bacan(display_long)|uniprotkb:GBAA_5694(locus name)	psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828655|imex:IM-13779-3221	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000060(BCCT transporter)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_001242469.1"	"efo:""Orphanet:136""|efo:""Orphanet:2591""|efo:""Orphanet:2789""|ensembl:ENSG00000074181.9(gene)|ensembl:ENST00000263388.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007411""(axon guidance)|go:""GO:0009986""(cell surface)|go:""GO:0014016""(neuroblast differentiation)|go:""GO:0019899""(enzyme binding)|go:""GO:0030900""(forebrain development)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043235""(receptor complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048663""(neuron fate commitment)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0072104""(glomerular capillary formation)|go:""GO:1902895""(positive regulation of miRNA transcription)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|rcsb pdb:6XSW|rcsb pdb:8OS0|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802|refseq:NP_000426.2|dip:DIP-39827N|panther:PTHR45836(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:/tOiU2i3Pj5531YNTX3x8RYSwk01392	rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606	intact-crc:2164BC257A86B607|rigid:l6PHIOGs3fb16gDsc6iyxVIH/Fk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3T9	uniprotkb:Q81P27	intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992.6	intact:EBI-2814639|uniprotkb:Q6KRC1|uniprotkb:Q6HX99	psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym)	psi-mi:proa_bacan(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:BA_2992(locus name)|uniprotkb:GBAA_2992(locus name)|uniprotkb:BAS2781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828682|imex:IM-13779-3220	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056473.2|ensembl:ENSG00000188976.11(gene)|ensembl:ENST00000327044.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002903""(negative regulation of B cell apoptotic process)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0030690""(Noc1p-Noc2p complex)|go:""GO:0030691""(Noc2p-Noc3p complex)|go:""GO:0031491""(nucleosome binding)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|reactome:R-HSA-6804756|panther:PTHR12687(orthology-group)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|go:""GO:0004350""(glutamate-5-semialdehyde dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0050661""(NADP binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:NP_845325.1|refseq:YP_029039.1|refseq:WP_001006638.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606	rogid:2iR76/3cLX7gyVDMLNG2KEyBoMY1392	intact-crc:D6EFB7B5DF93E817|rigid:IgE/5Lgf9zeIvpRCuVawgQ7cVII	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PRR8	uniprotkb:Q9ULX3	intact:EBI-2811394|uniprotkb:Q6I2G7|uniprotkb:Q6KW94|uniprotkb:E9R8J0|uniprotkb:E9R8J1|uniprotkb:Q81U80|uniprotkb:A0A0F7RLC1	intact:EBI-373285|uniprotkb:Q7L6B7|uniprotkb:Q7M4M4|uniprotkb:Q7Z4B5|uniprotkb:Q9NWB0|ensembl:ENSP00000268802.5	psi-mi:a0a6l8prr8_bacan(display_long)|uniprotkb:GBAA_1004(locus name)	psi-mi:nob1_human(display_long)|uniprotkb:NOB1(gene name)|psi-mi:NOB1(display_short)|uniprotkb:Protein ART-4(gene name synonym)|uniprotkb:Phosphorylation regulatory protein HP-10(gene name synonym)|uniprotkb:ART4(gene name synonym)|uniprotkb:NOB1P(gene name synonym)|uniprotkb:PSMD8BP1(gene name synonym)|uniprotkb:MSTP158(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828689|imex:IM-13779-3219	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020843|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR011032(GroES-like)|go:""GO:0016651""(""oxidoreductase activity, acting on NAD(P)H"")|go:""GO:0070402""(NADPH binding)|refseq:WP_000902291.1|interpro:IPR036291"	"refseq:NP_054781.1|ensembl:ENSG00000141101.13(gene)|ensembl:ENST00000268802.10(transcript)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006364""(rRNA processing)|go:""GO:0007601""(visual perception)|go:""GO:0030490""(maturation of SSU-rRNA)|go:""GO:0030688""(preribosome, small subunit precursor)|go:""GO:0046872""(metal ion binding)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR014881(""Nin one binding (NOB1) Zn-ribbon like"")|interpro:IPR017117(D-site 20S pre-rRNA nuclease)|interpro:IPR033411|interpro:IPR033461|interpro:IPR036283|interpro:IPR039907|mint:Q9ULX3|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:7WTW|rcsb pdb:7WTX|rcsb pdb:7WTZ|rcsb pdb:7WU0|reactome:R-HSA-6791226|panther:PTHR12814(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bJoUAV4WZkl9RHHmLvJxDPIL7Wk1392	rogid:/Xk2PcxpyxjcG5gvs2VtLK6QmvA9606	intact-crc:179349B7484E1E1F|rigid:wE1wLqOvWFQh94QJGhPNx4CE8mM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81NN0	uniprotkb:P46531	intact:EBI-2820443|uniprotkb:Q6KQY6|uniprotkb:Q6HWU8	intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587.1	psi-mi:glsa2_bacan(display_long)|uniprotkb:glsA2(gene name)|psi-mi:glsA2(display_short)|uniprotkb:glsA-2(gene name synonym)|uniprotkb:BA_3155(locus name)|uniprotkb:GBAA_3155(locus name)|uniprotkb:BAS2932(locus name)	psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828662|imex:IM-13779-3218	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000588653.1|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|go:""GO:0004359""(glutaminase activity)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006543""(glutamine catabolic process)|refseq:NP_845472.1|refseq:YP_029190.1"	"ensembl:ENSG00000148400.13(gene)|ensembl:ENST00000651671.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000987""(cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001554""(luteolysis)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001889""(liver development)|go:""GO:0001947""(heart looping)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002052""(positive regulation of neuroblast proliferation)|go:""GO:0002085""(inhibition of neuroepithelial cell differentiation)|go:""GO:0002193""(MAML1-RBP-Jkappa- ICN1 complex)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003157""(endocardium development)|go:""GO:0003160""(endocardium morphogenesis)|go:""GO:0003162""(atrioventricular node development)|go:""GO:0003169""(coronary vein morphogenesis)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0003182""(coronary sinus valve morphogenesis)|go:""GO:0003184""(pulmonary valve morphogenesis)|go:""GO:0003192""(mitral valve formation)|go:""GO:0003198""(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003207""(cardiac chamber formation)|go:""GO:0003208""(cardiac ventricle morphogenesis)|go:""GO:0003209""(cardiac atrium morphogenesis)|go:""GO:0003213""(cardiac right atrium morphogenesis)|go:""GO:0003214""(cardiac left ventricle morphogenesis)|go:""GO:0003219""(cardiac right ventricle formation)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003241""(growth involved in heart morphogenesis)|go:""GO:0003252""(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:""GO:0003270""(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:""GO:0003273""(cell migration involved in endocardial cushion formation)|go:""GO:0003332""(negative regulation of extracellular matrix constituent secretion)|go:""GO:0003344""(pericardium morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006955""(immune response)|go:""GO:0006959""(humoral immune response)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007221""(positive regulation of transcription of Notch receptor target)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007386""(compartment pattern specification)|go:""GO:0007411""(axon guidance)|go:""GO:0007440""(foregut morphogenesis)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009912""(auditory receptor cell fate commitment)|go:""GO:0009957""(epidermal cell fate specification)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010614""(negative regulation of cardiac muscle hypertrophy)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0010812""(negative regulation of cell-substrate adhesion)|go:""GO:0010832""(negative regulation of myotube differentiation)|go:""GO:0014031""(mesenchymal cell development)|go:""GO:0014807""(regulation of somitogenesis)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0019899""(enzyme binding)|go:""GO:0021515""(cell differentiation in spinal cord)|go:""GO:0021915""(neural tube development)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0030900""(forebrain development)|go:""GO:0031069""(hair follicle morphogenesis)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032966""(negative regulation of collagen biosynthetic process)|go:""GO:0035116""(embryonic hindlimb morphogenesis)|go:""GO:0035148""(tube formation)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042246""(tissue regeneration)|go:""GO:0042670""(retinal cone cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045603""(positive regulation of endothelial cell differentiation)|go:""GO:0045608""(negative regulation of inner ear auditory receptor cell differentiation)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045955""(negative regulation of calcium ion-dependent exocytosis)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046533""(negative regulation of photoreceptor cell differentiation)|go:""GO:0046579""(positive regulation of Ras protein signal transduction)|go:""GO:0048103""(somatic stem cell division)|go:""GO:0048708""(astrocyte differentiation)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048711""(positive regulation of astrocyte differentiation)|go:""GO:0048715""(negative regulation of oligodendrocyte differentiation)|go:""GO:0048754""(branching morphogenesis of an epithelial tube)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0055008""(cardiac muscle tissue morphogenesis)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060271""(cilium assembly)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0060354""(negative regulation of cell adhesion molecule production)|go:""GO:0060379""(cardiac muscle cell myoblast differentiation)|go:""GO:0060411""(cardiac septum morphogenesis)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060528""(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:""GO:0060740""(prostate gland epithelium morphogenesis)|go:""GO:0060768""(regulation of epithelial cell proliferation involved in prostate gland development)|go:""GO:0060842""(arterial endothelial cell differentiation)|go:""GO:0060843""(venous endothelial cell differentiation)|go:""GO:0060948""(cardiac vascular smooth muscle cell development)|go:""GO:0060956""(endocardial cell differentiation)|go:""GO:0060979""(vasculogenesis involved in coronary vascular morphogenesis)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0061101""(neuroendocrine cell differentiation)|go:""GO:0061344""(regulation of cell adhesion involved in heart morphogenesis)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0062043""(positive regulation of cardiac epithelial to mesenchymal transition)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070986""(left/right axis specification)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0071372""(cellular response to follicle-stimulating hormone stimulus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072017""(distal tubule development)|go:""GO:0072044""(collecting duct development)|go:""GO:0072091""(regulation of stem cell proliferation)|go:""GO:0072144""(glomerular mesangial cell development)|go:""GO:0072148""(epithelial cell fate commitment)|go:""GO:0072538""(T-helper 17 type immune response)|go:""GO:0090051""(negative regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0097400""(interleukin-17-mediated signaling pathway)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099565""(chemical synaptic transmission, postsynaptic)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140537""(transcription regulator activator activity)|go:""GO:1901201""(regulation of extracellular matrix assembly)|go:""GO:1902263""(apoptotic process involved in embryonic digit morphogenesis)|go:""GO:1902339""(positive regulation of apoptotic process involved in morphogenesis)|go:""GO:1903849""(positive regulation of aorta morphogenesis)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2000811""(negative regulation of anoikis)|go:""GO:2000974""(negative regulation of pro-B cell differentiation)|go:""GO:2001027""(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|rcsb pdb:1PB5|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|interpro:IPR049883|interpro:IPR051355|mint:P46531|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|rcsb pdb:8OR5|rcsb pdb:8ORY|rcsb pdb:8ORZ|rcsb pdb:9B3G|rcsb pdb:9B3N|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9793380|reactome:R-HSA-9818030|reactome:R-HSA-9818749|reactome:R-HSA-9824272|refseq:NP_060087.3|dip:DIP-29919N|efo:""Orphanet:402075""|efo:""Orphanet:974""|panther:PTHR45836(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:BIz9rHS/CqwS+6izEipBr6bK2H01392	rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606	intact-crc:997FC7AF37CFA2C9|rigid:ko5DMBpGSOnahRWL1+NpSDua4Lo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PK55	uniprotkb:O75323	intact:EBI-2819409|uniprotkb:Q6I0Z2|uniprotkb:Q6KUU6|uniprotkb:E9QZF5|uniprotkb:E9QZF6|uniprotkb:Q81SR0|uniprotkb:A0A0F7REQ8	intact:EBI-307133|uniprotkb:O43801|uniprotkb:Q53X96|uniprotkb:C9IYJ3|ensembl:ENSP00000313050.3	psi-mi:a0a6l8pk55_bacan(display_long)|uniprotkb:GBAA_1586(locus name)	psi-mi:nips2_human(display_long)|uniprotkb:NIPSNAP2(gene name)|psi-mi:NIPSNAP2(display_short)|uniprotkb:GBAS(gene name synonym)|uniprotkb:Glioblastoma-amplified sequence(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828708|imex:IM-13779-3226	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR027417|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|go:""GO:0016818""(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|refseq:WP_000493684.1|interpro:IPR045028"	"refseq:NP_001189398.1|refseq:NP_001474.1|ensembl:ENSG00000146729.10(gene)|ensembl:ENST00000322090.8(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:1901843""(positive regulation of high voltage-gated calcium channel activity)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|interpro:IPR051557|mint:O75323|reactome:R-HSA-9013407|reactome:R-HSA-9013409|dip:DIP-33564N|panther:PTHR21017(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:YPFQAm544pyXyffToEz30B8JO9I1392	rogid:sfBQGdtSVoH21kBu/Bz9x8x3KWU9606	intact-crc:50795BAC462E2FE4|rigid:BVGta9+aTZcJwtoajNyw/72XQ9A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3T9	uniprotkb:A0A6L7HRM6	intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992.6	intact:EBI-2828699|uniprotkb:Q6I4G6|uniprotkb:Q6KY67|uniprotkb:E9QR97|uniprotkb:E9QR98|uniprotkb:Q81VG2	psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym)	psi-mi:a0a6l7hrm6_bacan(display_long)|uniprotkb:GBAA_0244(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828696|imex:IM-13779-3225	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056473.2|ensembl:ENSG00000188976.11(gene)|ensembl:ENST00000327044.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002903""(negative regulation of B cell apoptotic process)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0030690""(Noc1p-Noc2p complex)|go:""GO:0030691""(Noc2p-Noc3p complex)|go:""GO:0031491""(nucleosome binding)|go:""GO:0034644""(cellular response to UV)|go:""GO:0042273""(ribosomal large subunit biogenesis)|go:""GO:0042393""(histone binding)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|reactome:R-HSA-6804756|panther:PTHR12687(orthology-group)"	"interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR005829(Sugar transporter, conserved site)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_000799743.1|interpro:IPR036259|interpro:IPR050497"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606	rogid:6TVdpKnwfq7JRPaWSamHV4T9KZk1392	intact-crc:3B2C9A565FF62595|rigid:dXd4Jl1sdGp/trGT0JJmT0i11kM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6KC79	uniprotkb:A0A6L7HJD9	intact:EBI-722767|uniprotkb:Q6KCD6|uniprotkb:Q6N080|uniprotkb:Q6ZT92|uniprotkb:Q7Z2E6|uniprotkb:Q8N4M5|uniprotkb:Q9Y6Y3|uniprotkb:Q9Y6Y4|ensembl:ENSP00000282516.8	intact:EBI-2818003|uniprotkb:Q6KS63|uniprotkb:Q6HY50|uniprotkb:E9R233|uniprotkb:E9R234|uniprotkb:Q81PX9|uniprotkb:A0A0F7RI73	psi-mi:nipbl_human(display_long)|uniprotkb:Delangin(gene name synonym)|uniprotkb:SCC2 homolog(gene name synonym)|uniprotkb:NIPBL(gene name)|psi-mi:NIPBL(display_short)|uniprotkb:IDN3(gene name synonym)|uniprotkb:SCC2(gene name synonym)	psi-mi:a0a6l7hjd9_bacan(display_long)|uniprotkb:GBAA_2661(locus name)|uniprotkb:adP1(gene name)|psi-mi:adP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828722|imex:IM-13779-3227	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164190.19(gene)|ensembl:ENST00000282516.13(transcript)|go:""GO:0000070""(mitotic sister chromatid segregation)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0001656""(metanephros development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006974""(DNA damage response)|go:""GO:0007064""(mitotic sister chromatid cohesion)|go:""GO:0007420""(brain development)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008104""(protein localization)|go:""GO:0032039""(integrator complex)|go:""GO:0032116""(SMC loading complex)|go:""GO:0034087""(establishment of mitotic sister chromatid cohesion)|go:""GO:0034088""(maintenance of mitotic sister chromatid cohesion)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0035115""(embryonic forelimb morphogenesis)|go:""GO:0035136""(forelimb morphogenesis)|go:""GO:0035261""(external genitalia morphogenesis)|go:""GO:0036033""(mediator complex binding)|go:""GO:0040018""(positive regulation of multicellular organism growth)|go:""GO:0042471""(ear morphogenesis)|go:""GO:0042634""(regulation of hair cycle)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045778""(positive regulation of ossification)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048557""(embryonic digestive tract morphogenesis)|go:""GO:0048565""(digestive tract development)|go:""GO:0048589""(developmental growth)|go:""GO:0048592""(eye morphogenesis)|go:""GO:0048638""(regulation of developmental growth)|go:""GO:0048703""(embryonic viscerocranium morphogenesis)|go:""GO:0050890""(cognition)|go:""GO:0060325""(face morphogenesis)|go:""GO:0061010""(gallbladder development)|go:""GO:0061038""(uterus morphogenesis)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0061780""(obsolete mitotic cohesin loading)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070087""(chromo shadow domain binding)|go:""GO:0071169""(establishment of protein localization to chromatin)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0090694""(Scc2-Scc4 cohesin loading complex)|go:""GO:1990414""(replication-born double-strand break repair via sister chromatid exchange)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2001224""(positive regulation of neuron migration)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024986|interpro:IPR026003|interpro:IPR033031|mint:Q6KC79|rcsb pdb:6WG3|rcsb pdb:6WGE|rcsb pdb:7W1M|reactome:R-HSA-2470946|refseq:NP_056199.2|refseq:NP_597677.2|refseq:XP_016864819.1|efo:""Orphanet:199""|efo:""Orphanet:329802""|dip:DIP-29199N|panther:PTHR21704(orthology-group)"	interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|refseq:WP_000845176.1|interpro:IPR050491	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:RaZLQ4CmlJD/3QUl7n1JKBT23GM9606	rogid:3qobiBGRawBE8K1XIyLVSFvnDtE1392	intact-crc:1BE46E7122FD3886|rigid:ieIY6jubLq3u47IHpoCyOpKA2Aw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HA34	uniprotkb:P14543	intact:EBI-2819995|uniprotkb:Q6KJI8|uniprotkb:Q6HQ44|uniprotkb:E9R0U6|uniprotkb:E9R0U7|uniprotkb:Q81JK1|uniprotkb:A0A1V4B6Z1	intact:EBI-2828729|uniprotkb:Q86XD7|uniprotkb:Q5TAF3|uniprotkb:Q5TAF2|uniprotkb:Q14942|uniprotkb:Q59FL2|ensembl:ENSP00000264187.6	psi-mi:a0a6l7ha34_bacan(display_long)|uniprotkb:dbpA(gene name)|psi-mi:dbpA(display_short)|uniprotkb:GBAA_5703(locus name)	psi-mi:nid1_human(display_long)|uniprotkb:NID1(gene name)|psi-mi:NID1(display_short)|uniprotkb:NID(gene name synonym)|uniprotkb:Entactin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828739|imex:IM-13779-3223	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028619|interpro:IPR005580(DbpA, RNA-binding)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0009409""(response to cold)|go:""GO:0016787""(hydrolase activity)|go:""GO:0033592""(RNA strand annealing activity)|go:""GO:0034458""(3'-5' RNA helicase activity)|refseq:WP_000039360.1|interpro:IPR050547|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)"	"efo:""Orphanet:269215""|ensembl:ENSG00000116962.15(gene)|ensembl:ENST00000264187.7(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0032836""(glomerular basement membrane development)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0043236""(laminin binding)|go:""GO:0043237""(laminin-1 binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071711""(basement membrane organization)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:0110011""(regulation of basement membrane organization)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036857|interpro:IPR049883|interpro:IPR050778|mint:P14543|reactome:R-HSA-1474228|reactome:R-HSA-3000157|refseq:NP_002499.2|panther:PTHR46513(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FUK12JdMNXvGAVxuqcOH2FSM/f01392	rogid:xlqES3FTQirfYhb0lB7RfGpFQms9606	intact-crc:39245DCBA0D32516|rigid:4I5kERjkm1BJYBMVaWzIeS7y1c8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75323	uniprotkb:A0A6L8PT45	intact:EBI-307133|uniprotkb:O43801|uniprotkb:Q53X96|uniprotkb:C9IYJ3|ensembl:ENSP00000313050.3	intact:EBI-2825742|uniprotkb:Q6KVF1|uniprotkb:Q6I1K2|uniprotkb:E9RAT2|uniprotkb:E9RAT3|uniprotkb:Q81TC5|uniprotkb:A0A0J1HZ85	psi-mi:nips2_human(display_long)|uniprotkb:NIPSNAP2(gene name)|psi-mi:NIPSNAP2(display_short)|uniprotkb:GBAS(gene name synonym)|uniprotkb:Glioblastoma-amplified sequence(gene name synonym)	psi-mi:a0a6l8pt45_bacan(display_long)|uniprotkb:queE(gene name)|psi-mi:queE(display_short)|uniprotkb:Queuosine biosynthesis protein QueE(gene name synonym)|uniprotkb:GBAA_1361(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828715|imex:IM-13779-3224	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001189398.1|refseq:NP_001474.1|ensembl:ENSG00000146729.10(gene)|ensembl:ENST00000322090.8(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:1901843""(positive regulation of high voltage-gated calcium channel activity)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|interpro:IPR051557|mint:O75323|reactome:R-HSA-9013407|reactome:R-HSA-9013409|dip:DIP-33564N|panther:PTHR21017(orthology-group)"	"interpro:IPR017742(""7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE"")|interpro:IPR007197(Radical SAM)|interpro:IPR024924|go:""GO:0000287""(magnesium ion binding)|go:""GO:0008616""(queuosine biosynthetic process)|go:""GO:0016840""(carbon-nitrogen lyase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:1904047""(S-adenosyl-L-methionine binding)|refseq:WP_000036288.1|interpro:IPR013785(Aldolase-type TIM barrel)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:sfBQGdtSVoH21kBu/Bz9x8x3KWU9606	rogid:gTku1wUCCSbVrsy9wG9sItVGxNc1392	intact-crc:CF7A1294539387F1|rigid:pCIn0Y2ZSwYTrV3EHAhWk4TNeeo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14543	uniprotkb:A0A6L7H7R4	intact:EBI-2828729|uniprotkb:Q86XD7|uniprotkb:Q5TAF3|uniprotkb:Q5TAF2|uniprotkb:Q14942|uniprotkb:Q59FL2|ensembl:ENSP00000264187.6	intact:EBI-2814598|uniprotkb:Q6I1X0|uniprotkb:Q6KVR2|uniprotkb:E9RAJ8|uniprotkb:E9RAJ9|uniprotkb:Q81TN9|uniprotkb:A0A1S0QL17	psi-mi:nid1_human(display_long)|uniprotkb:NID1(gene name)|psi-mi:NID1(display_short)|uniprotkb:NID(gene name synonym)|uniprotkb:Entactin(gene name synonym)	psi-mi:a0a6l7h7r4_bacan(display_long)|uniprotkb:GBAA_1231(locus name)|uniprotkb:rfbD(gene name)|psi-mi:rfbD(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828753|imex:IM-13779-3228	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:269215""|ensembl:ENSG00000116962.15(gene)|ensembl:ENST00000264187.7(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0032836""(glomerular basement membrane development)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0043236""(laminin binding)|go:""GO:0043237""(laminin-1 binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071711""(basement membrane organization)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:0110011""(regulation of basement membrane organization)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036857|interpro:IPR049883|interpro:IPR050778|mint:P14543|reactome:R-HSA-1474228|reactome:R-HSA-3000157|refseq:NP_002499.2|panther:PTHR46513(orthology-group)"	"interpro:IPR005913(dTDP-4-dehydrorhamnose reductase)|rcsb pdb:3SC6|go:""GO:0000166""(nucleotide binding)|go:""GO:0005829""(cytosol)|go:""GO:0008831""(dTDP-4-dehydrorhamnose reductase activity)|go:""GO:0019305""(dTDP-rhamnose biosynthetic process)|go:""GO:0045226""(obsolete extracellular polysaccharide biosynthetic process)|refseq:WP_000664670.1|interpro:IPR029903|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xlqES3FTQirfYhb0lB7RfGpFQms9606	rogid:TGeZ8RAjVc+Mul2hbC3OCTywlmI1392	intact-crc:70F994304C647EE9|rigid:Knehw0DBpAdgcaS1s4saOsy3Bx8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HB40	uniprotkb:P14543	intact:EBI-2812761|uniprotkb:Q6I3J5|uniprotkb:Q6KXA8|uniprotkb:E9R2F8|uniprotkb:E9R2F9|uniprotkb:A0A2P0H9V3|uniprotkb:Q81VA8	intact:EBI-2828729|uniprotkb:Q86XD7|uniprotkb:Q5TAF3|uniprotkb:Q5TAF2|uniprotkb:Q14942|uniprotkb:Q59FL2|ensembl:ENSP00000264187.6	psi-mi:a0a6l7hb40_bacan(display_long)|uniprotkb:GBAA_0589(locus name)	psi-mi:nid1_human(display_long)|uniprotkb:NID1(gene name)|psi-mi:NID1(display_short)|uniprotkb:NID(gene name synonym)|uniprotkb:Entactin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828746|imex:IM-13779-3230	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR001041(Ferredoxin)|interpro:IPR006478(Formate dehydrogenase, alpha subunit)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR019574|interpro:IPR050123|interpro:IPR027467|go:""GO:0003954""(NADH dehydrogenase activity)|go:""GO:0008863""(""formate dehydrogenase (NAD+) activity"")|go:""GO:0015942""(formate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_000840648.1|interpro:IPR036010|interpro:IPR041924"	"efo:""Orphanet:269215""|ensembl:ENSG00000116962.15(gene)|ensembl:ENST00000264187.7(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0032836""(glomerular basement membrane development)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0043236""(laminin binding)|go:""GO:0043237""(laminin-1 binding)|go:""GO:0043394""(proteoglycan binding)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0051149""(positive regulation of muscle cell differentiation)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071711""(basement membrane organization)|go:""GO:0098637""(protein complex involved in cell-matrix adhesion)|go:""GO:0110011""(regulation of basement membrane organization)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036857|interpro:IPR049883|interpro:IPR050778|mint:P14543|reactome:R-HSA-1474228|reactome:R-HSA-3000157|refseq:NP_002499.2|panther:PTHR46513(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QNDnbGYfnNxnQEMZtqgLWO6/cVs1392	rogid:xlqES3FTQirfYhb0lB7RfGpFQms9606	intact-crc:9CF3A02EB4F2113A|rigid:rH01YzkuSrqeqmzgSqfBxO5kYsA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q81NT0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2828783|uniprotkb:Q6HX00|uniprotkb:Q6KR32	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:pxpa_bacan(display_long)|uniprotkb:pxpA(gene name)|psi-mi:pxpA(display_short)|uniprotkb:""5-oxoprolinase (ATP-hydrolyzing) subunit A""(gene name synonym)|uniprotkb:BAS2880(locus name)|uniprotkb:BA_3095(locus name)|uniprotkb:GBAA_3095(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828780|imex:IM-13779-3232	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR005501(LamB/YcsF)|refseq:WP_000207358.1|go:""GO:0005524""(ATP binding)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0017168""(""5-oxoprolinase (ATP-hydrolyzing) activity"")|refseq:NP_845422.1|refseq:YP_029138.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:Xuyh2Z/yhJ6Eq1PjIpOJosyxLFs1392	intact-crc:418D91007801890F|rigid:45s/LBAQXJJoVicS7OqItlhAKe0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KK8	uniprotkb:P19838	intact:EBI-2822258|uniprotkb:Q6KLB4|uniprotkb:E9R5P7	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q81kk8_bacan(display_long)|uniprotkb:GBAA_4989(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828760|imex:IM-13779-3231	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:IiAIRE+C5ddv3SFzgMBN5yxqO8Q1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:B4EA24007AE0CD1B|rigid:GUcHOM86gijLzxP9a/5c2LvIp5k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WY7	uniprotkb:P19838	intact:EBI-2828770|uniprotkb:Q6KK41|uniprotkb:Q6HQS3	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:thic_bacan(display_long)|uniprotkb:thiC(gene name)|psi-mi:thiC(display_short)|uniprotkb:Hydroxymethylpyrimidine phosphate synthase(gene name synonym)|uniprotkb:BA_5463(locus name)|uniprotkb:GBAA_5463(locus name)|uniprotkb:BAS5076(locus name)|uniprotkb:Thiamine biosynthesis protein ThiC(gene name synonym)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828767|imex:IM-13779-3229	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002817(Thiamine biosynthesis protein ThiC)|interpro:IPR025747|refseq:WP_000814464.1|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0016830""(carbon-carbon lyase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR038521|interpro:IPR037509|refseq:NP_847631.1|refseq:YP_031315.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:jaOVEgxTfyoMUe4tG8REbhotAeQ1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:DE5178007994BAEC|rigid:rYCo8hdM7v98UF3eMGvA8ZBDSRA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81TM1	uniprotkb:P19838	intact:EBI-2828795|uniprotkb:Q6I1V1|uniprotkb:Q6KVP3	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:trpd_bacan(display_long)|uniprotkb:trpD(gene name)|psi-mi:trpD(display_short)|uniprotkb:BA_1250(locus name)|uniprotkb:GBAA_1250(locus name)|uniprotkb:BAS1158(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828792|imex:IM-13779-3233	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005940(Anthranilate phosphoribosyl transferase)|interpro:IPR000312(Glycosyl transferase, family 3)|interpro:IPR017459(Glycosyl transferase, family 3, N-terminal)|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004048""(anthranilate phosphoribosyltransferase activity)|go:""GO:0005829""(cytosol)|refseq:WP_001067344.1|interpro:IPR035902|interpro:IPR036320|refseq:NP_843722.1|refseq:YP_027429.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:4oBJRbB1jy0+/63FTbSaft0/koQ1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:ABE2EB00785A0514|rigid:8I0Ki1jJRU79vpJt0f2+GS4jobc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P1I7	uniprotkb:P19838	intact:EBI-2809746|uniprotkb:Q6KXV0|uniprotkb:Q6I440|uniprotkb:E9RCC7|uniprotkb:E9RCC8|uniprotkb:A0A2P0H989|uniprotkb:Q81Z98	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l8p1i7_bacan(display_long)|uniprotkb:GBAA_0374(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828812|imex:IM-13779-3234	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017501(Phage infection protein, YhgE,  C-terminal)|interpro:IPR017500(Phage infection protein, YhgE,  N-terminal)|interpro:IPR051328|go:""GO:0016020""(membrane)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR013525(ABC-2 type transporter)|refseq:WP_000810134.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Km4jDuu44pVTrI8b6www/dkgkrY1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:2D2ECA28E9975B89|rigid:wI9zFWMmNLrM3WMvEDN4V/YwBMA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P864	uniprotkb:P19838	intact:EBI-2818016|uniprotkb:Q6I481|uniprotkb:Q6KXY7|uniprotkb:E9R899|uniprotkb:E9R8A0|uniprotkb:A0A2P0H999|uniprotkb:Q81ZD5	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l8p864_bacan(display_long)|uniprotkb:GBAA_0334(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828805|imex:IM-13779-3236	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR001269(Dihydrouridine synthase, DuS)|interpro:IPR018517|interpro:IPR024036|go:""GO:0000049""(tRNA binding)|go:""GO:0017150""(tRNA dihydrouridine synthase activity)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_000566690.1|interpro:IPR035587"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Ws2lbrRnpZcDQtnDQAA8PqhrQ641392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:2513C49C660B4B67|rigid:dBptgq7gKDpCNbNaXNowOtF8fAo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AGH4	uniprotkb:P19838	intact:EBI-2811747|uniprotkb:Q6KPR0|uniprotkb:Q6HVI9|uniprotkb:E9QZA8|uniprotkb:E9QZA9|uniprotkb:Q81Y98|uniprotkb:A0A0F7REA7	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6h3agh4_bacan(display_long)|uniprotkb:parE(gene name)|psi-mi:parE(display_short)|uniprotkb:Topoisomerase IV subunit B(gene name synonym)|uniprotkb:GBAA_3657(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828819|imex:IM-13779-3237	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011557(DNA gyrase, subunit B)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR005740(DNA topoisomerase IV, subunit B, Gram-positive)|interpro:IPR006171(TOPRIM)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0006265""(DNA topological change)|go:""GO:0007059""(chromosome segregation)|go:""GO:0034335""(DNA negative supercoiling activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_001062204.1|interpro:IPR036890|interpro:IPR000565(DNA topoisomerase, type IIA, subunit B)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:yUlUe2myCjax59Zrv/o54Ei+VvU1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:A89FA49550520D13|rigid:4JUytUsP/iccQd0ZZqm8GiVykAE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A348A7I7	uniprotkb:P19838	intact:EBI-2828826|uniprotkb:Q6KPL6|uniprotkb:E9QZ63|uniprotkb:Q81Y52	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a348a7i7_bacan(display_long)|uniprotkb:GBAA_3705(locus name)|uniprotkb:Proline permease(gene name synonym)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828830|imex:IM-13779-3235	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000687602.1|interpro:IPR011851(Sodium/proline symporter)|interpro:IPR001734(Na+/solute symporter)|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0015193""(L-proline transmembrane transporter activity)|go:""GO:0015824""(proline transport)|go:""GO:0031402""(sodium ion binding)|interpro:IPR038377|interpro:IPR050277"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:LLobNlKL5xnTjt7Je8e1G54+0HY1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:C86031904D4D87D2|rigid:p6DLz9hVFx/2NnIbecfl3B11dJU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L8PM54	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2828837|uniprotkb:Q6KPE8|uniprotkb:Q6HV76|uniprotkb:E9R982|uniprotkb:E9R983|uniprotkb:A0A2P0HHR6|uniprotkb:Q81XX9	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l8pm54_bacan(display_long)|uniprotkb:GBAA_3785(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828842|imex:IM-13779-3242	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR006433(Peptidase U35, phage prohead HK97)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|interpro:IPR054613|refseq:WP_001043897.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:/RaJsBo2AcnNO+M+TPf58v9yxLA1392	intact-crc:5B3FBAC9752335F6|rigid:5sI9RLqJ8dXQyui3IH4ke7qMnN0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A2P0HL95	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2817321|uniprotkb:Q6KK70|uniprotkb:Q6HQV1|uniprotkb:E9RBJ7|uniprotkb:E9RBJ8|uniprotkb:Q81X16|uniprotkb:A0A0F7RAQ3	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a2p0hl95_bacan(display_long)|uniprotkb:GBAA_5433(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828861|imex:IM-13779-3241	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR003331(UDP-N-acetylglucosamine 2-epimerase)|go:""GO:0008761""(UDP-N-acetylglucosamine 2-epimerase activity)|interpro:IPR029767|refseq:WP_000140127.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:dI0p4eSbZCInr9ZLr0IAKrP1oeM1392	intact-crc:F7D29ED6F6626E70|rigid:CwWWdvAiEfkiTN/CXJ+zzCZxHrQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L8PJK6	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2812240|uniprotkb:Q6KX38|uniprotkb:Q6I3C1|uniprotkb:E9QUC2|uniprotkb:E9QUC3|uniprotkb:Q81V38|uniprotkb:A0A0F7RJ14	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l8pjk6_bacan(display_long)|uniprotkb:rbsK(gene name)|psi-mi:rbsK(display_short)|uniprotkb:GBAA_0665(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828875|imex:IM-13779-3240	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR002173(Carbohydrate/puine kinase, PfkB, conserved site)|interpro:IPR011877(Ribokinase, bacterial)|interpro:IPR002139(Ribokinase)|interpro:IPR029056|go:""GO:0004747""(ribokinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019303""(D-ribose catabolic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_001132852.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:bCT50FjU1Cr3U/oOrt5sbgTy9Ts1392	intact-crc:578529DAA8B423B9|rigid:0XW/3vOf/3nXKWkoQjHaYewEmak	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L8NU76	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2828849|uniprotkb:Q6HV49|uniprotkb:Q6KPC0|uniprotkb:E9R0I8|uniprotkb:E9R0I9|uniprotkb:Q81XU9|uniprotkb:A0A0F7RA37	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l8nu76_bacan(display_long)|uniprotkb:GBAA_3819(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828854|imex:IM-13779-3238	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	interpro:IPR011741(Phage conserved hypothetical protein, C-terminal)|refseq:WP_000067428.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:Q2l8qliTHBnxHDbZ9ep0MRabXtI1392	intact-crc:4E2D41AC59FF5240|rigid:7mdC6ZMSDMYPafXO6ERYEDkna90	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7R9M2	uniprotkb:P19838	intact:EBI-2822179	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a0f7r9m2_bacan(display_long)|uniprotkb:BA_0075(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828868|imex:IM-13779-3239	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:Q81VW4(uniprot-removed-ac)|interpro:IPR001269(Dihydrouridine synthase, DuS)|interpro:IPR004652(Dihydrouridine synthase TIM-barrel, NifR3)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018517|interpro:IPR024036|go:""GO:0000049""(tRNA binding)|go:""GO:0017150""(tRNA dihydrouridine synthase activity)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR035587|refseq:NP_842644.2"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:RUulaRiqK4I282kg3wMNy/BYiHY1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:6590314B991F2FC5|rigid:MIDKhtiJSC9Wbk+vbXfDJNSx7Yg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6H3AGL8	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2813001|uniprotkb:Q6KVU2|uniprotkb:Q6I204|uniprotkb:E9RDJ5|uniprotkb:E9RDJ6|uniprotkb:Q81TS1|uniprotkb:A0A1Q4M339|uniprotkb:A0A1T3UY59	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6h3agl8_bacan(display_long)|uniprotkb:GBAA_1194(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828896|imex:IM-13779-3244	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"refseq:WP_000854348.1|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013563(Oligopeptide/dipeptide ABC transporter, C-terminal)|interpro:IPR050388|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0015833""(peptide transport)|go:""GO:0016887""(ATP hydrolysis activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:U6dsNIBEfPjIZyfya6IjHw84HNs1392	intact-crc:F77B5AC7B0F7ED96|rigid:vzO9XFyy8HbYzXC/nrN//dtFQ08	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81UM1	uniprotkb:P19838	intact:EBI-2810062|uniprotkb:Q6KWM8|uniprotkb:E9QUN3	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:q81um1_bacan(display_long)|uniprotkb:GBAA_0843(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828882|imex:IM-13779-3245	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018028|interpro:IPR010582(Catalase-related)|interpro:IPR024712|interpro:IPR020835|interpro:IPR002226(Catalase)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR043156|interpro:IPR029062|go:""GO:0004096""(catalase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0020037""(heme binding)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR041399"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:emjR7zrszb3kjc9o/hpyL6qIl941392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:3B3F9A00785A0548|rigid:JiFV7Wq7TGAZxUmVz/Y0zg9wD3Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NXF0	uniprotkb:P19838	intact:EBI-2822995|uniprotkb:Q6I194|uniprotkb:Q6KV44|uniprotkb:E9RDE2|uniprotkb:E9RDE3|uniprotkb:Q81T13|uniprotkb:A0A1Q4M3L5	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l8nxf0_bacan(display_long)|uniprotkb:GBAA_1479(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828915|imex:IM-13779-3243	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR002763(Protein of unknown function DUF72)|refseq:WP_000897346.1|interpro:IPR036520	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:u1sZiTg4rdlUG2mmKDCV0by4crM1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:B839472A105BE978|rigid:jUQ4UwsdHd0beke7FQVY8HDAuPg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PBB8	uniprotkb:P19838	intact:EBI-2810547|uniprotkb:Q6KWH8|uniprotkb:Q6I2Q0|uniprotkb:E9QV37|uniprotkb:E9QV38|uniprotkb:Q81UH0|uniprotkb:A0A0F7RGK4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l8pbb8_bacan(display_long)|uniprotkb:GBAA_0902(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828889|imex:IM-13779-3246	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003462(Ornithine cyclodeaminase/mu-crystallin)|interpro:IPR023401|go:""GO:0005737""(cytoplasm)|refseq:WP_000960276.1|interpro:IPR036291"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:A71+jKUZLyfZWvjcF3aw6Zz7k5w1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:E487266C4EC9D905|rigid:Zq+ttBv8J4PoEiMpXdx7d1pcEgA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PI29	uniprotkb:P19838	intact:EBI-2828906|uniprotkb:Q6KVT4|uniprotkb:Q6I1Z5|uniprotkb:E9QWC0|uniprotkb:E9QWC1|uniprotkb:Q81TR1|uniprotkb:A0A0F7RM60	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l8pi29_bacan(display_long)|uniprotkb:GBAA_1205(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828903|imex:IM-13779-3247	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010330(Competence-induced protein CoiA-like)|interpro:IPR021176|refseq:WP_000612267.1	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:hAcSucsFr4h8epYkkvsRjBOvcCM1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:ED15F7E516968447|rigid:4+xuYU9GVP0us2RcdmjoZ5bEpvk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HHX2	uniprotkb:P19838	intact:EBI-2812285|uniprotkb:Q6KUB0|uniprotkb:Q6I0E0|uniprotkb:E9QSI8|uniprotkb:E9QSI9|uniprotkb:Q81S59|uniprotkb:A0A0F7RKM4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l7hhx2_bacan(display_long)|uniprotkb:GBAA_1815(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828959|imex:IM-13779-3250	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025450|go:""GO:0016020""(membrane)|refseq:WP_000789548.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:g0iSNc7Mh4tgNaBj+nHYsEjH5sY1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:F086483A02712F0E|rigid:FB1qGTezcDRtTNMQA7RPCRxD8Sk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HNT3	uniprotkb:P19838	intact:EBI-2828922|uniprotkb:Q6I157|uniprotkb:Q6KV11|uniprotkb:E9R0T3|uniprotkb:E9R0T4|uniprotkb:Q81SX9|uniprotkb:A0A0F7RKD4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l7hnt3_bacan(display_long)|uniprotkb:GBAA_1515(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828927|imex:IM-13779-3248	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023856|refseq:WP_001168485.1|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR036188|interpro:IPR050097"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:ZTlXNnJo0XcyAsjsTscSHRHcHvM1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:13BFC6C011AE9831|rigid:7HqOYKHxlfj8mIATJrzwkW5Xo6k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q81SC3	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2828948|uniprotkb:Q6KUG9|uniprotkb:E9R058	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q81sc3_bacan(display_long)|uniprotkb:GBAA_1737(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828952|imex:IM-13779-3252	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|go:""GO:0004521""(RNA endonuclease activity)|interpro:IPR036866|interpro:IPR050698"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:cmGKnMp6wVabkiFFjHEAdymeLh01392	intact-crc:1F5EBC0078E0D788|rigid:xwHE2CVSbrsonmgrQpDtv+ExliE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L7H6C0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2814287|uniprotkb:Q6I0R3|uniprotkb:Q6KUL9|uniprotkb:E9RCU3|uniprotkb:E9RCU4|uniprotkb:Q81SI0|uniprotkb:A0A0F7RJD1	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l7h6c0_bacan(display_long)|uniprotkb:flgK(gene name)|psi-mi:flgK(display_short)|uniprotkb:GBAA_1669(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828941|imex:IM-13779-3249	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR053927|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009424""(bacterial-type flagellum hook)|go:""GO:0044780""(bacterial-type flagellum assembly)|refseq:WP_001239678.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:VOkH/wThG14shDsSxBIqKBRImSc1392	intact-crc:1ACA0BDE60715573|rigid:hIhIrNOVFWqqgBgZ2qU3Ew3E/u8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:P19838	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828934|imex:IM-13779-3251	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:575712489B234986|rigid:3XkwOj8Q+Hyrwb2qTXcq+A4IzJI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L8PE10	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2818555|uniprotkb:Q6KTZ8|uniprotkb:Q6I019|uniprotkb:E9R2B8|uniprotkb:E9R2B9|uniprotkb:Q81RU2|uniprotkb:A0A0F7RJ75	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l8pe10_bacan(display_long)|uniprotkb:GBAA_1945(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828966|imex:IM-13779-3256	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR014216(""ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD"")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR039421|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034040""(ATPase-coupled lipid transmembrane transporter activity)|go:""GO:0042883""(cysteine transport)|go:""GO:0140359""(ABC-type transporter activity)|refseq:WP_000824065.1|interpro:IPR036640"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:7XCFAONaGDISWIyfy6ZvZMJ+Gh81392	intact-crc:CF50A31D035167DD|rigid:tfaQgpLBIdHlEXspPzTuqdbp1LU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AKG3	uniprotkb:P19838	intact:EBI-2820051|uniprotkb:Q6KRD6|uniprotkb:Q6HXB7|uniprotkb:E9R9R2|uniprotkb:E9R9R3|uniprotkb:Q81P43|uniprotkb:A0A1Q4LYM0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6h3akg3_bacan(display_long)|uniprotkb:GBAA_2975(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828980|imex:IM-13779-3255	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025997|interpro:IPR028082|rcsb pdb:4PZ0|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|interpro:IPR030159|refseq:WP_000823631.1|interpro:IPR050555"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:d4rJUp7zJD5EoI8pkswYZrjgWXg1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:160B8F0C07209705|rigid:FQXlls9AbqUSZEwpYWdIS9Bap2o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H421	uniprotkb:P19838	intact:EBI-2810652|uniprotkb:Q6KSG7|uniprotkb:Q6HYF9|uniprotkb:E9R9F4|uniprotkb:E9R9F5|uniprotkb:Q81Q87|uniprotkb:A0A0F7RDV9	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l7h421_bacan(display_long)|uniprotkb:GBAA_2546(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828973|imex:IM-13779-3253	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR013560(Protein of unknown function DUF1722)|interpro:IPR007553(Protein of unknown function DUF523)|interpro:IPR017087(Uncharacterised conserved protein UCP037004)|refseq:WP_001248630.1	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:2helogO2D/G85c/K2apFD3gNVOc1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:286016E99F3431D0|rigid:UfYdFPVtZ+GrDgqyy+AkYHCVbxY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PZY4	uniprotkb:P19838	intact:EBI-2814949|uniprotkb:Q6HWU0|uniprotkb:Q6KQY0|uniprotkb:E9QXP8|uniprotkb:E9QXP9|uniprotkb:A0A2P0HG91|uniprotkb:Q81NM4	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	psi-mi:a0a6l8pzy4_bacan(display_long)|uniprotkb:GBAA_3164(locus name)	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828987|imex:IM-13779-3254	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018028|interpro:IPR010582(Catalase-related)|interpro:IPR024708|interpro:IPR024711|interpro:IPR020835|interpro:IPR002226(Catalase)|interpro:IPR011614(Catalase, N-terminal)|go:""GO:0004096""(catalase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0020037""(heme binding)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000829762.1"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:72lPT3Lz14HhvItYpYjV0jEJBBs1392	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	intact-crc:EBCC8E53890DD98D|rigid:0mG941SPgF7okmrEUFDQ1+I9yKk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L8P2X1	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2811664|uniprotkb:Q6HWH8|uniprotkb:Q6KQM9|uniprotkb:E9QRE5|uniprotkb:E9QRE6|uniprotkb:Q81NC2|uniprotkb:A0A0F7R9W0	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l8p2x1_bacan(display_long)|uniprotkb:GBAA_3288(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2828994|imex:IM-13779-3257	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR043502|interpro:IPR017961|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR043128|interpro:IPR024728|interpro:IPR050116|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0009432""(SOS response)|go:""GO:0042276""(error-prone translesion synthesis)|refseq:WP_000272549.1|interpro:IPR036775"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:fUIT+VEfXS3bjWD3plCkaA/yspE1392	intact-crc:2C77907325FCA0E2|rigid:sMfrRsy9XN6w/Tkru4NwepeO5EY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L7HD93	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2829001|uniprotkb:Q6HSL0|uniprotkb:Q6KLV4|uniprotkb:E9QRR4|uniprotkb:E9QRR5|uniprotkb:Q81L57|uniprotkb:A0A0F7RBC1	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l7hd93_bacan(display_long)|uniprotkb:GBAA_4774(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829006|imex:IM-13779-3258	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000221093.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:D2H9/9jUb/287A89AQOnDVaj5GM1392	intact-crc:96D0D2929A22FBD7|rigid:i3XcAp6JIguj6CFDy+8JkaQmoMg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L8P1L2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2829013|uniprotkb:Q6KL39|uniprotkb:Q6HRT1|uniprotkb:E9RA50|uniprotkb:E9RA51|uniprotkb:Q81KC6|uniprotkb:A0A1Q4M4T3	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l8p1l2_bacan(display_long)|uniprotkb:GBAA_5075(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829018|imex:IM-13779-3260	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR005218(Conserved hypothetical protein CHP00147)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|rcsb pdb:3S40|rcsb pdb:3T5P|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|rcsb pdb:4WRR|go:""GO:0004143""(ATP-dependent diacylglycerol kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0008654""(phospholipid biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000167888.1|interpro:IPR050187|interpro:IPR045540"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:vpDAOitK1fTe6n4OQM/qqz8CHz81392	intact-crc:2F0863B2EA25C616|rigid:R1VLv0a+NIIFuAmZwhjg11fryfA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6H3A7A0	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2816408|uniprotkb:Q6KJM0|uniprotkb:Q6HQ84|uniprotkb:E9R659|uniprotkb:E9R660|uniprotkb:Q81JP0|uniprotkb:A0A0J1HQJ7	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6h3a7a0_bacan(display_long)|uniprotkb:PN/PL/PM kinase(gene name synonym)|uniprotkb:Pyridoxal kinase(gene name synonym)|uniprotkb:Pyridoxamine kinase(gene name synonym)|uniprotkb:Vitamin B6 kinase(gene name synonym)|uniprotkb:GBAA_5663(locus name)|uniprotkb:thiD2(gene name)|psi-mi:thiD2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829038|imex:IM-13779-3259	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR013749(Phosphomethylpyrimidine kinase type-1)|interpro:IPR004399(Phosphomethylpyrimidine kinase type-2)|interpro:IPR029056|go:""GO:0005829""(cytosol)|go:""GO:0008902""(hydroxymethylpyrimidine kinase activity)|go:""GO:0008972""(phosphomethylpyrimidine kinase activity)|go:""GO:0009228""(thiamine biosynthetic process)|refseq:WP_000174258.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:ZKs9DIeVsjFfhDrSTBn0LaAf4oc1392	intact-crc:E1DD1FC725163756|rigid:cDlILnMqx4l/jbqjS5x7oqxNfYU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:A0A6L8PFB2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2829028|uniprotkb:Q6KL03|uniprotkb:Q6HRN7|uniprotkb:E9R238|uniprotkb:E9R239|uniprotkb:Q81K86|uniprotkb:A0A0F7R6N9	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:a0a6l8pfb2_bacan(display_long)|uniprotkb:glgP(gene name)|psi-mi:glgP(display_short)|uniprotkb:GBAA_5119(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829025|imex:IM-13779-3261	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR035090|go:""GO:0005737""(cytoplasm)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0008184""(glycogen phosphorylase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0031220""(maltodextrin phosphorylase activity)|refseq:WP_000494082.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:PxK6pkjew8lALPkWemFwJzj27nc1392	intact-crc:B1C87881D0855227|rigid:YBOBhxK4Lp/tRTbCoxZTjWosuVk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16236	uniprotkb:Q81T09	intact:EBI-2007911|uniprotkb:Q53RW6|uniprotkb:Q59HH2|uniprotkb:Q96F71|uniprotkb:B2RBU2|uniprotkb:B4E338|uniprotkb:E9PGJ7|ensembl:ENSP00000380252.3|intact:EBI-28978278	intact:EBI-2829072|uniprotkb:Q6I190|uniprotkb:Q6KV40	psi-mi:nf2l2_human(display_long)|uniprotkb:NFE2L2(gene name)|psi-mi:NFE2L2(display_short)|uniprotkb:NRF2(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 2(gene name synonym)	psi-mi:deod_bacan(display_long)|uniprotkb:deoD(gene name)|psi-mi:deoD(display_short)|uniprotkb:BA_1483(locus name)|uniprotkb:GBAA_1483(locus name)|uniprotkb:BAS1372(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829069|imex:IM-13779-3265	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:619979""|panther:PTHR24411(orthology-group)|dip:DIP-29971N|ensembl:ENSG00000116044.17(gene)|ensembl:ENST00000397062.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006954""(inflammatory response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0010499""(proteasomal ubiquitin-independent protein catabolic process)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0036499""(PERK-mediated unfolded protein response)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045088""(regulation of innate immune response)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0046223""(aflatoxin catabolic process)|go:""GO:0046326""(positive regulation of D-glucose import)|go:""GO:0061431""(cellular response to methionine)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071280""(cellular response to copper ion)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071498""(cellular response to fluid shear stress)|go:""GO:0071499""(cellular response to laminar fluid shear stress)|go:""GO:0072593""(reactive oxygen species metabolic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0110076""(negative regulation of ferroptosis)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1900038""(negative regulation of cellular response to hypoxia)|go:""GO:1900407""(regulation of cellular response to oxidative stress)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903788""(positive regulation of glutathione biosynthetic process)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904753""(negative regulation of vascular associated smooth muscle cell migration)|go:""GO:2000060""(positive regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000121""(regulation of removal of superoxide radicals)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR047167|mint:Q16236|rcsb pdb:2FLU|rcsb pdb:2LZ1|rcsb pdb:3ZGC|rcsb pdb:4IFL|rcsb pdb:5WFV|rcsb pdb:6T7V|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2K|rcsb pdb:7O7B|rcsb pdb:7X5E|rcsb pdb:7X5F|rcsb pdb:7X5G|rcsb pdb:8EJR|rcsb pdb:8EJS|reactome:R-HSA-8951664|reactome:R-HSA-9679191|reactome:R-HSA-9707587|reactome:R-HSA-9707616|reactome:R-HSA-9755511|reactome:R-HSA-9759194|reactome:R-HSA-9762114|reactome:R-HSA-9818025|reactome:R-HSA-9818026|reactome:R-HSA-9818027|reactome:R-HSA-9818028|reactome:R-HSA-9818030|reactome:R-HSA-9818032|reactome:R-HSA-9818035|reactome:R-HSA-9818749|refseq:NP_001138884.1|refseq:NP_001138885.1|refseq:NP_001300829.1|refseq:NP_001300830.1|refseq:NP_006155.2"	"interpro:IPR004402(Purine nucleoside phosphorylase)|interpro:IPR018016|interpro:IPR000845(Nucleoside phosphorylase)|rcsb pdb:1XE3|rcsb pdb:2AC7|refseq:WP_000110707.1|go:""GO:0004731""(purine-nucleoside phosphorylase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006152""(purine nucleoside catabolic process)|interpro:IPR035994|refseq:NP_843936.1|refseq:YP_027641.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:EjSeL1dJClhC2vIPip6QDc8QAUk9606	rogid:JJFg2IGRkxOVVWKeQ/7iyJVK7VQ1392	intact-crc:A490387DE1E5866E|rigid:vP0xYmHxJIJyCt0bgvzdEfg8q2o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14494	uniprotkb:Q81UJ9	intact:EBI-2804436|uniprotkb:Q96FN6|uniprotkb:Q12877|uniprotkb:D3DTU3|uniprotkb:D3DTU5|ensembl:ENSP00000354855.3|intact:EBI-28976146	intact:EBI-2829085|uniprotkb:Q6KWK9|uniprotkb:Q6I2S8	psi-mi:nf2l1_human(display_long)|uniprotkb:HBZ17(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:TCF11(gene name synonym)|uniprotkb:Locus control region-factor 1(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 1(gene name synonym)|uniprotkb:Transcription factor 11(gene name synonym)|uniprotkb:NFE2L1(gene name)|psi-mi:NFE2L1(display_short)|uniprotkb:Nuclear factor erythroid 2-related factor 1(gene name synonym)|uniprotkb:Protein NRF1, p120 form(gene name synonym)	psi-mi:3mgh_bacan(display_long)|uniprotkb:BA_0869(locus name)|uniprotkb:GBAA_0869(locus name)|uniprotkb:BAS0826(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829082|imex:IM-13779-3263	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003195.1|refseq:XP_005257467.1|refseq:XP_005257469.1|ensembl:ENSG00000082641.16(gene)|ensembl:ENST00000362042.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008289""(lipid binding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0042802""(identical protein binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR047167|mint:Q14494|refseq:NP_001317191.1|panther:PTHR24411(orthology-group)"	"interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR003180(""Methylpurine-DNA glycosylase (MPG)"")|go:""GO:0003677""(DNA binding)|go:""GO:0003905""(alkylbase DNA N-glycosylase activity)|go:""GO:0006284""(base-excision repair)|refseq:WP_001148814.1|interpro:IPR036995|refseq:NP_843382.1|refseq:YP_027102.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/mXRFWPHxGFlrQmbhG3eDz9uXoc9606	rogid:IePo3rZsLVisJYjQOxnLtv6bKxo1392	intact-crc:4F54B74F5D0330D4|rigid:teEj3O5X0HZknYrTOO33IADDdCk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q81JG2	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2829048|uniprotkb:Q6KW67|uniprotkb:E9R401	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:q81jg2_bacan(display_long)|uniprotkb:GBAA_1034(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829045|imex:IM-13779-3262	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR001182(Cell cycle protein)|interpro:IPR047928|go:""GO:0005886""(plasma membrane)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0015648""(lipid-linked peptidoglycan transporter activity)|go:""GO:0016740""(transferase activity)|go:""GO:0032153""(cell division site)|go:""GO:0051301""(cell division)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:3iby9N9U9JLK/gVR/ciTGanY36Q1392	intact-crc:407B550078BD5C78|rigid:gnUgGoQ1+yGWL3pz846LYZoY2uI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P19838	uniprotkb:Q81L15	intact:EBI-300010|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|ensembl:ENSP00000378297.4|ensembl:ENSP00000424790.1|uniprotkb:A8K5Y5|uniprotkb:B3KVE8	intact:EBI-2829056|uniprotkb:Q6HSH0|uniprotkb:Q6KLR5	psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym)	psi-mi:if3_bacan(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:BA_4819(locus name)|uniprotkb:GBAA_4819(locus name)|uniprotkb:BAS4471(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829062|imex:IM-13779-3264	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000109320.14(gene)|ensembl:ENST00000394820.8(transcript)|ensembl:ENST00000505458.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010744""(positive regulation of macrophage derived foam cell differentiation)|go:""GO:0010884""(positive regulation of lipid storage)|go:""GO:0010956""(negative regulation of calcidiol 1-monooxygenase activity)|go:""GO:0010957""(negative regulation of vitamin D biosynthetic process)|go:""GO:0032375""(negative regulation of cholesterol transport)|go:""GO:0032695""(negative regulation of interleukin-12 production)|go:""GO:0033256""(I-kappaB/NF-kappaB complex)|go:""GO:0034097""(response to cytokine)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035525""(NF-kappaB p50/p65 complex)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042805""(actinin binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045087""(innate immune response)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0060056""(mammary gland involution)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071316""(cellular response to nicotine)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071354""(cellular response to interleukin-6)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071359""(cellular response to dsRNA)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097398""(cellular response to interleukin-17)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140367""(antibacterial innate immune response)|go:""GO:1900127""(positive regulation of hyaluronan biosynthetic process)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:2000630""(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|interpro:IPR047096|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:7LEQ|rcsb pdb:7LET|rcsb pdb:7LF4|rcsb pdb:7LFC|rcsb pdb:7RG4|rcsb pdb:7RG5|rcsb pdb:8TQD|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-9692916|reactome:R-HSA-9818749|reactome:R-HSA-9860927|refseq:NP_001158884.1|refseq:NP_001306155.1|refseq:NP_003989.2|dip:DIP-106N|efo:""Orphanet:1572""|panther:PTHR24169(orthology-group)"	"interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0043022""(ribosome binding)|interpro:IPR036787|interpro:IPR036788|refseq:NP_847022.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606	rogid:PZMLOSz2Kv5Z+3QMp/QCmqJe9dY1392	intact-crc:91C2730079389BF6|rigid:7c3oNHgN5GRd2GUiBvIrGXkCMZM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96SB3	uniprotkb:A0A6L8PEJ3	intact:EBI-351275|uniprotkb:Q8TCR9|intact:EBI-28984643|ensembl:ENSP00000478767.1|intact:EBI-4401886|uniprotkb:D3DTX6	intact:EBI-2813582|uniprotkb:Q6KXQ7|uniprotkb:Q6I3Z5|uniprotkb:E9QSX3|uniprotkb:E9QSX4|uniprotkb:Q81Z55|uniprotkb:A0A0F7RHX8	psi-mi:neb2_human(display_long)|uniprotkb:Neurabin-II(gene name synonym)|uniprotkb:Spinophilin(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)|uniprotkb:PPP1R9B(gene name)|psi-mi:PPP1R9B(display_short)|uniprotkb:PPP1R6(gene name synonym)	psi-mi:a0a6l8pej3_bacan(display_long)|uniprotkb:GBAA_0418(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829130|imex:IM-13779-3268	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108819.11(gene)|ensembl:ENST00000612501.2(transcript)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0001560""(regulation of cell growth by extracellular stimulus)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003006""(developmental process involved in reproduction)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007015""(actin filament organization)|go:""GO:0007096""(regulation of exit from mitosis)|go:""GO:0007612""(learning)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0008380""(RNA splicing)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016358""(dendrite development)|go:""GO:0016477""(cell migration)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019900""(kinase binding)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030175""(filopodium)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031175""(neuron projection development)|go:""GO:0031749""(D2 dopamine receptor binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0035094""(response to nicotine)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044326""(dendritic spine neck)|go:""GO:0044327""(dendritic spine head)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051015""(actin filament binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060179""(male mating behavior)|go:""GO:0061458""(reproductive system development)|go:""GO:0071315""(cellular response to morphine)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0097444""(spine apparatus)|refseq:NP_115984.3|go:""GO:0098890""(extrinsic component of postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1901653""(cellular response to peptide)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903119""(protein localization to actin cytoskeleton)|go:""GO:1904372""(positive regulation of protein localization to actin cortical patch)|go:""GO:1904373""(response to kainic acid)|go:""GO:1904386""(response to L-phenylalanine derivative)|go:""GO:1990778""(protein localization to cell periphery)|go:""GO:1990780""(cytoplasmic side of dendritic spine plasma membrane)|go:""GO:2000474""(regulation of opioid receptor signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:Q96SB3|panther:PTHR16154(orthology-group)"	"interpro:IPR038725|interpro:IPR012349(FMN-binding split barrel)|rcsb pdb:3EC6|interpro:IPR052917|go:""GO:0000166""(nucleotide binding)|refseq:WP_000550225.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:X6fQLpaYhXCqzRlQNEoX67P/HbU9606	rogid:qpjkJaDqcldmvViPZZlLcflrWiE1392	intact-crc:7D500068FC0F190E|rigid:cICCFlk+ehR9W9Li8w5Nqog1alg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HCP8	uniprotkb:Q8NC67	intact:EBI-2821310|uniprotkb:Q6KIX7|uniprotkb:E9R7F5|uniprotkb:Q81KI9	intact:EBI-2829094|uniprotkb:Q9NVY8|uniprotkb:Q8ND51|uniprotkb:Q96SP4|uniprotkb:Q7Z381|uniprotkb:J3KNF1|ensembl:ENSP00000455169.1	psi-mi:a0a6l7hcp8_bacan(display_long)|uniprotkb:GBAA_5008(locus name)	psi-mi:neto2_human(display_long)|uniprotkb:NETO2(gene name)|psi-mi:NETO2(display_short)|uniprotkb:BTCL2(gene name synonym)|uniprotkb:Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2(gene name synonym)|uniprotkb:UNQ1926/PRO4401(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829102|imex:IM-13779-3266	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR019712|refseq:WP_001102457.1	"refseq:NP_001188406.1|refseq:NP_060562.3|ensembl:ENSG00000171208.10(gene)|ensembl:ENST00000562435.6(transcript)|go:""GO:0014069""(postsynaptic density)|go:""GO:0035255""(ionotropic glutamate receptor binding)|go:""GO:0098696""(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099645""(neurotransmitter receptor localization to postsynaptic specialization membrane)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|panther:PTHR24251(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kpxe94ig3X8QHkO5x5D+ay6X+jk1392	rogid:zYMe/vy3cmCbdG0CsP9t9WiHmf49606	intact-crc:4F8B94117F8292B3|rigid:dk4I+v69YnRduFypfPDzAgA4XaU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VT8	uniprotkb:Q96SB3	intact:EBI-2811891|uniprotkb:Q6I4U2	intact:EBI-351275|uniprotkb:Q8TCR9|intact:EBI-28984643|ensembl:ENSP00000478767.1|intact:EBI-4401886|uniprotkb:D3DTX6	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	psi-mi:neb2_human(display_long)|uniprotkb:Neurabin-II(gene name synonym)|uniprotkb:Spinophilin(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)|uniprotkb:PPP1R9B(gene name)|psi-mi:PPP1R9B(display_short)|uniprotkb:PPP1R6(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829137|imex:IM-13779-3270	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"ensembl:ENSG00000108819.11(gene)|ensembl:ENST00000612501.2(transcript)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0001560""(regulation of cell growth by extracellular stimulus)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003006""(developmental process involved in reproduction)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007015""(actin filament organization)|go:""GO:0007096""(regulation of exit from mitosis)|go:""GO:0007612""(learning)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0008380""(RNA splicing)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016358""(dendrite development)|go:""GO:0016477""(cell migration)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019900""(kinase binding)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030175""(filopodium)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031175""(neuron projection development)|go:""GO:0031749""(D2 dopamine receptor binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0035094""(response to nicotine)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044326""(dendritic spine neck)|go:""GO:0044327""(dendritic spine head)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051015""(actin filament binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060179""(male mating behavior)|go:""GO:0061458""(reproductive system development)|go:""GO:0071315""(cellular response to morphine)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0097444""(spine apparatus)|refseq:NP_115984.3|go:""GO:0098890""(extrinsic component of postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1901653""(cellular response to peptide)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903119""(protein localization to actin cytoskeleton)|go:""GO:1904372""(positive regulation of protein localization to actin cortical patch)|go:""GO:1904373""(response to kainic acid)|go:""GO:1904386""(response to L-phenylalanine derivative)|go:""GO:1990778""(protein localization to cell periphery)|go:""GO:1990780""(cytoplasmic side of dendritic spine plasma membrane)|go:""GO:2000474""(regulation of opioid receptor signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:Q96SB3|panther:PTHR16154(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	rogid:X6fQLpaYhXCqzRlQNEoX67P/HbU9606	intact-crc:C35D9A2009E0EBC9|rigid:u+3UePm9bif33hCOJrA04d/Dnrs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WM3	uniprotkb:Q9HB63	intact:EBI-2811277|uniprotkb:Q6KP05|uniprotkb:Q6HUS3	intact:EBI-743459|uniprotkb:Q658K9|uniprotkb:Q7L3F1|uniprotkb:Q7L9D6|uniprotkb:Q7Z5B6|uniprotkb:Q9BZP1|uniprotkb:Q9NT44|uniprotkb:Q9P133|uniprotkb:B2RNC2|ensembl:ENSP00000340998.4	psi-mi:if2_bacan(display_long)|uniprotkb:infB(gene name)|psi-mi:infB(display_short)|uniprotkb:BA_3950(locus name)|uniprotkb:GBAA_3950(locus name)|uniprotkb:BAS3664(locus name)	psi-mi:net4_human(display_long)|uniprotkb:Beta-netrin(gene name synonym)|uniprotkb:Hepar-derived netrin-like protein(gene name synonym)|uniprotkb:NTN4(gene name)|psi-mi:NTN4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829109|imex:IM-13779-3269	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR053905|interpro:IPR044145|interpro:IPR006847(Translation initiation factor IF-2, N-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000178(Initiation factor 2)|interpro:IPR023115|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005829""(cytosol)|refseq:WP_000036339.1|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR036925|refseq:NP_846193.1|refseq:YP_029915.1"	"refseq:NP_067052.2|refseq:NP_001316629.1|refseq:NP_001316630.1|refseq:NP_001316631.1|dip:DIP-46274N|ensembl:ENSG00000074527.13(gene)|ensembl:ENST00000343702.9(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009888""(tissue development)|go:""GO:0016322""(neuron remodeling)|go:""GO:0016477""(cell migration)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0043237""(laminin-1 binding)|go:""GO:0043256""(laminin complex)|go:""GO:0060668""(regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling)|go:""GO:0070831""(basement membrane assembly)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|interpro:IPR035811|interpro:IPR050440|mint:Q9HB63|reactome:R-HSA-3000171|reactome:R-HSA-373752|panther:PTHR10574(orthology-group)|ensembl:ENSP00000340998.4|ensembl:ENST00000344911.8|ensembl:ENSP00000339436.4|ensembl:ENST00000538383.5|ensembl:ENSP00000444432.1|ensembl:ENST00000553059.1|ensembl:ENSP00000447292.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:ZybMBb8EpwfT4Z43NREw57NAPPc1392	rogid:Wiq3R27SFsSneLrCDSpL19glpxE9606	intact-crc:015D656EE00AD84D|rigid:dgv51bv9qEroa49danbLQN5+z9Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92859	uniprotkb:A0A6L7H2I0	intact:EBI-2829116|uniprotkb:B7ZKM9|uniprotkb:O00340|uniprotkb:Q17RX1|uniprotkb:B7ZKN0|ensembl:ENSP00000261908.6|ensembl:ENSP00000341198.5|intact:EBI-28985104	intact:EBI-2819062|uniprotkb:Q6KQ42|uniprotkb:E9R158|uniprotkb:A0A2P0HGR3|uniprotkb:Q81YN3	psi-mi:neo1_human(display_long)|uniprotkb:NEO1(gene name)|psi-mi:NEO1(display_short)|uniprotkb:IGDCC2(gene name synonym)|uniprotkb:NGN(gene name synonym)|uniprotkb:Immunoglobulin superfamily DCC subclass member 2(gene name synonym)	psi-mi:a0a6l7h2i0_bacan(display_long)|uniprotkb:GBAA_3506(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829123|imex:IM-13779-3267	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002490.2|refseq:NP_001166095.1|refseq:NP_001166094.1|ensembl:ENSG00000067141.17(gene)|ensembl:ENST00000261908.11(transcript)|ensembl:ENST00000339362.9(transcript)|go:""GO:0001764""(neuron migration)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0007155""(cell adhesion)|go:""GO:0007411""(axon guidance)|go:""GO:0007520""(myoblast fusion)|go:""GO:0009306""(protein secretion)|go:""GO:0009986""(cell surface)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0039706""(co-receptor binding)|go:""GO:0044295""(axonal growth cone)|go:""GO:0045296""(cadherin binding)|go:""GO:0048681""(negative regulation of axon regeneration)|go:""GO:0050709""(negative regulation of protein secretion)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0070700""(BMP receptor binding)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098797""(plasma membrane protein complex)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099550""(trans-synaptic signaling, modulating synaptic transmission)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:Q92859|rcsb pdb:1X5F|rcsb pdb:1X5G|rcsb pdb:1X5H|rcsb pdb:1X5I|rcsb pdb:1X5J|rcsb pdb:1X5K|rcsb pdb:3P4L|reactome:R-HSA-373752|reactome:R-HSA-525793|dip:DIP-46272N|panther:PTHR44170(orthology-group)"	interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|refseq:WP_000769754.1|interpro:IPR050491	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:qfhSmuj+gTFt2FkBaL/aUUWeKrY9606	rogid:Rn0bV28FF7QPmttgacWHy0ClQtM1392	intact-crc:B06E7DA6BB033DEF|rigid:nqRKcxMlpPBU3VEETy+jwj71NxU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HDR8	uniprotkb:O60502	intact:EBI-2813601|uniprotkb:Q6KMC4|uniprotkb:Q6HT37|uniprotkb:E9QVK2|uniprotkb:E9QVK3|uniprotkb:Q81LM9|uniprotkb:A0A0F7R6G5	intact:EBI-715814|uniprotkb:O75166|uniprotkb:Q86WV0|uniprotkb:Q8IV98|uniprotkb:Q9BVA5|uniprotkb:Q9HAR0|uniprotkb:B7WPB9|uniprotkb:D3DR79|uniprotkb:E9PGF9|ensembl:ENSP00000354850.3	psi-mi:a0a6l7hdr8_bacan(display_long)|uniprotkb:GBAA_4586(locus name)	psi-mi:oga_human(display_long)|uniprotkb:OGA(gene name)|psi-mi:OGA(display_short)|uniprotkb:Beta-N-acetylglucosaminidase(gene name synonym)|uniprotkb:Beta-N-acetylhexosaminidase(gene name synonym)|uniprotkb:Beta-hexosaminidase(gene name synonym)|uniprotkb:HEXC(gene name synonym)|uniprotkb:KIAA0679(gene name synonym)|uniprotkb:MEA5(gene name synonym)|uniprotkb:MGEA5(gene name synonym)|uniprotkb:Meningioma-expressed antigen 5(gene name synonym)|uniprotkb:N-acetyl-beta-D-glucosaminidase(gene name synonym)|uniprotkb:N-acetyl-beta-glucosaminidase(gene name synonym)|uniprotkb:Nuclear cytoplasmic O-GlcNAcase and acetyltransferase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829175|imex:IM-13779-3271	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR019774|go:""GO:0005506""(iron ion binding)|go:""GO:0009072""(aromatic amino acid metabolic process)|go:""GO:0016714""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen)|refseq:WP_000163221.1|interpro:IPR036329|interpro:IPR036951"	"refseq:NP_001135906.1|refseq:NP_036347.1|ensembl:ENSG00000198408.14(gene)|ensembl:ENST00000361464.8(transcript)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006044""(N-acetylglucosamine metabolic process)|go:""GO:0006493""(protein O-linked glycosylation)|go:""GO:0006516""(glycoprotein catabolic process)|go:""GO:0006517""(protein deglycosylation)|go:""GO:0009100""(glycoprotein metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016231""(beta-N-acetylglucosaminidase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0102571""(""[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity"")|interpro:IPR011496(Hyaluronidase eukaryotic/prokaryotic)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR051822|mint:O60502|rcsb pdb:2YDQ|rcsb pdb:5M7R|rcsb pdb:5M7S|rcsb pdb:5M7T|rcsb pdb:5M7U|rcsb pdb:5TKE|rcsb pdb:5UHK|rcsb pdb:5UHL|rcsb pdb:5UHO|rcsb pdb:5UHP|rcsb pdb:5UN8|rcsb pdb:5UN9|rcsb pdb:5VVO|rcsb pdb:5VVT|rcsb pdb:5VVU|rcsb pdb:5VVV|rcsb pdb:5VVX|rcsb pdb:6HKI|rcsb pdb:6PM9|rcsb pdb:7OU6|rcsb pdb:7YEH|rcsb pdb:8P0L|panther:PTHR13170(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UgqbKGjZURf/eUAUwQIMUjWsS6Q1392	rogid:KEvP6+2BWwsxrs8hsIjQhKAQGVo9606	intact-crc:F02612767BA70A8A|rigid:SsoUjUXqtBYHZkYNE1gImdla3qY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WK3	uniprotkb:Q14686	intact:EBI-2826194|uniprotkb:Q6KNY5|uniprotkb:Q6HUQ4	intact:EBI-78670|uniprotkb:A6NLF1|uniprotkb:Q9NTZ9|uniprotkb:Q9UH74|uniprotkb:Q9UK86|uniprotkb:B2RMN5|uniprotkb:E1P5P7|ensembl:ENSP00000351894.2|ensembl:ENSP00000363929.2	"psi-mi:trmfo_bacan(display_long)|uniprotkb:trmFO(gene name)|psi-mi:trmFO(display_short)|uniprotkb:gid(gene name synonym)|uniprotkb:""Folate-dependent tRNA (uracil-5-)-methyltransferase""(gene name synonym)|uniprotkb:""Folate-dependent tRNA(M-5-U54)-methyltransferase""(gene name synonym)|uniprotkb:BA_3970(locus name)|uniprotkb:GBAA_3970(locus name)|uniprotkb:BAS3683(locus name)"	psi-mi:ncoa6_human(display_long)|uniprotkb:NCOA6(gene name)|psi-mi:NCOA6(display_short)|uniprotkb:KIAA0181(gene name synonym)|uniprotkb:RAP250(gene name synonym)|uniprotkb:Amplified in breast cancer protein 3(gene name synonym)|uniprotkb:Cancer-amplified transcriptional coactivator ASC-2(gene name synonym)|uniprotkb:Activating signal cointegrator 2(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor-activating protein, 250 kDa(gene name synonym)|uniprotkb:Nuclear receptor coactivator RAP250(gene name synonym)|uniprotkb:Thyroid hormone receptor-binding protein(gene name synonym)|uniprotkb:AIB3(gene name synonym)|uniprotkb:TRBP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829182|imex:IM-13779-3275	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004417(Gid protein)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0047151""(""tRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent"")|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|interpro:IPR040131|refseq:NP_846213.1|refseq:YP_029934.1|refseq:WP_003161605.1"	"refseq:NP_001229468.1|refseq:NP_054790.2|panther:PTHR15690(orthology-group)|refseq:NP_001305169.1|dip:DIP-30934N|ensembl:ENSG00000198646.14(gene)|ensembl:ENST00000359003.7(transcript)|ensembl:ENST00000374796.6(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0009725""(response to hormone)|go:""GO:0019899""(enzyme binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|interpro:IPR026638|interpro:IPR032715|mint:Q14686|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/10	rogid:ZK5+I3fqFuyTXl2yUtsPcns5frI1392	rogid:0PZz93t/oHYDVeiX+8NqjSlpNRo9606	intact-crc:C84E0E930D975941|rigid:wZ89VvLfItM4taR4FaAr+cPYRNw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AJ28	uniprotkb:Q9NXR1	intact:EBI-2829167|uniprotkb:Q6KLI1|uniprotkb:E9R738|uniprotkb:Q81KS6|uniprotkb:A0A2B0Y418	intact:EBI-941227|uniprotkb:Q49AQ2|ensembl:ENSP00000379642.1|ensembl:ENSP00000379643.1|ensembl:ENSP00000488050.1|ensembl:ENSP00000488199.1|ensembl:ENSP00000501936.1|ensembl:ENSP00000502160.1|ensembl:ENSP00000502354.1|ensembl:ENSP00000502635.1	psi-mi:a0a6h3aj28_bacan(display_long)|uniprotkb:GBAA_4914(locus name)	psi-mi:nde1_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short)|uniprotkb:NUDE(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829164|imex:IM-13779-3273	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_000066437.1"	"ensembl:ENSG00000072864.16(gene)|ensembl:ENSG00000275911.3(gene)|ensembl:ENST00000396354.6(transcript)|ensembl:ENST00000396355.5(transcript)|ensembl:ENST00000631844.1(transcript)|ensembl:ENST00000631923.1(transcript)|ensembl:ENST00000674554.1(transcript)|ensembl:ENST00000674888.1(transcript)|ensembl:ENST00000675926.1(transcript)|ensembl:ENST00000675951.1(transcript)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000776""(kinetochore)|go:""GO:0001764""(neuron migration)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007100""(mitotic centrosome separation)|go:""GO:0007405""(neuroblast proliferation)|go:""GO:0008017""(microtubule binding)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0031616""(spindle pole centrosome)|go:""GO:0032154""(cleavage furrow)|go:""GO:0042802""(identical protein binding)|go:""GO:0045202""(synapse)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0051298""(centrosome duplication)|go:""GO:0051301""(cell division)|go:""GO:0051303""(establishment of chromosome localization)|go:""GO:0051642""(centrosome localization)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9NXR1|rcsb pdb:7E1T|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|refseq:NP_001137451.1|refseq:NP_060138.1|refseq:XP_016878838.1|refseq:XP_016878845.1|efo:""Orphanet:2177""|efo:""Orphanet:443162""|efo:""Orphanet:89844""|panther:PTHR10921(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OOwQ0R71r0h8mgM52F5enp82wDk1392	rogid:H769EmQerGWsy6Zud3BBzkAuQw49606	intact-crc:E48AF3BCE82E457E|rigid:KLE4i88jBZt/j1K7wdFN0NIlB9o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96SB3	uniprotkb:A0A6L7HBL2	intact:EBI-351275|uniprotkb:Q8TCR9|intact:EBI-28984643|ensembl:ENSP00000478767.1|intact:EBI-4401886|uniprotkb:D3DTX6	intact:EBI-2829144|uniprotkb:Q6I368|uniprotkb:Q6KWY8|uniprotkb:E9QS16|uniprotkb:E9QS17|uniprotkb:Q81UY7|uniprotkb:A0A0F7RLT4	psi-mi:neb2_human(display_long)|uniprotkb:Neurabin-II(gene name synonym)|uniprotkb:Spinophilin(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)|uniprotkb:PPP1R9B(gene name)|psi-mi:PPP1R9B(display_short)|uniprotkb:PPP1R6(gene name synonym)	psi-mi:a0a6l7hbl2_bacan(display_long)|uniprotkb:GBAA_0719(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829150|imex:IM-13779-3274	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108819.11(gene)|ensembl:ENST00000612501.2(transcript)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0001560""(regulation of cell growth by extracellular stimulus)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003006""(developmental process involved in reproduction)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007015""(actin filament organization)|go:""GO:0007096""(regulation of exit from mitosis)|go:""GO:0007612""(learning)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0008380""(RNA splicing)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016358""(dendrite development)|go:""GO:0016477""(cell migration)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019900""(kinase binding)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030175""(filopodium)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030425""(dendrite)|go:""GO:0030426""(growth cone)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031175""(neuron projection development)|go:""GO:0031749""(D2 dopamine receptor binding)|go:""GO:0032587""(ruffle membrane)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0035094""(response to nicotine)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0044326""(dendritic spine neck)|go:""GO:0044327""(dendritic spine head)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051015""(actin filament binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060179""(male mating behavior)|go:""GO:0061458""(reproductive system development)|go:""GO:0071315""(cellular response to morphine)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0097444""(spine apparatus)|refseq:NP_115984.3|go:""GO:0098890""(extrinsic component of postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1901653""(cellular response to peptide)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1903119""(protein localization to actin cytoskeleton)|go:""GO:1904372""(positive regulation of protein localization to actin cortical patch)|go:""GO:1904373""(response to kainic acid)|go:""GO:1904386""(response to L-phenylalanine derivative)|go:""GO:1990778""(protein localization to cell periphery)|go:""GO:1990780""(cytoplasmic side of dendritic spine plasma membrane)|go:""GO:2000474""(regulation of opioid receptor signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:Q96SB3|panther:PTHR16154(orthology-group)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR027463|refseq:WP_000375588.1|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:X6fQLpaYhXCqzRlQNEoX67P/HbU9606	rogid:SEhknWI/faoIBf+OV++0mQYzUxQ1392	intact-crc:EE3579F0D7835115|rigid:nqdLHU3Civu8/dvogu0pUYCh4Zo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HLZ2	uniprotkb:Q92597	intact:EBI-2822704|uniprotkb:Q6I1V2|uniprotkb:Q6KVP4|uniprotkb:E9QXG7|uniprotkb:E9QXG8|uniprotkb:Q81TM2|uniprotkb:A0A0F7RFK1	intact:EBI-716486|uniprotkb:O15207|uniprotkb:Q9NYR6|uniprotkb:Q9UK29|uniprotkb:Q6IBG2|uniprotkb:B3KR80|uniprotkb:B7Z446|ensembl:ENSP00000319977.8|ensembl:ENSP00000404854.2	psi-mi:a0a6l7hlz2_bacan(display_long)|uniprotkb:GBAA_1249(locus name)	psi-mi:ndrg1_human(display_long)|uniprotkb:N-myc downstream-regulated gene 1 protein(gene name synonym)|uniprotkb:Differentiation-related gene 1 protein(gene name synonym)|uniprotkb:Reducing agents and tunicamycin-responsive protein(gene name synonym)|uniprotkb:Nickel-specific induction protein Cap43(gene name synonym)|uniprotkb:Rit42(gene name synonym)|uniprotkb:NDRG1(gene name)|psi-mi:NDRG1(display_short)|uniprotkb:CAP43(gene name synonym)|uniprotkb:DRG1(gene name synonym)|uniprotkb:RTP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829157|imex:IM-13779-3272	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006221(Glutamine amidotransferase of anthranilate synthase)|interpro:IPR017926|interpro:IPR029062|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004049""(anthranilate synthase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006541""(glutamine metabolic process)|refseq:WP_000636353.1|interpro:IPR050472"	"ensembl:ENSG00000104419.17(gene)|ensembl:ENST00000323851.13(transcript)|ensembl:ENST00000414097.6(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0007165""(signal transduction)|go:""GO:0008017""(microtubule binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010038""(response to metal ion)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032287""(peripheral nervous system myelin maintenance)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045576""(mast cell activation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071456""(cellular response to hypoxia)|interpro:IPR004142(Ndr)|interpro:IPR029058|mint:Q92597|rcsb pdb:6ZMM|reactome:R-HSA-6803205|refseq:NP_001128714.1|refseq:NP_001245361.1|refseq:NP_001245362.1|refseq:NP_006087.2|efo:""Orphanet:99950""|panther:PTHR11034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VEw7iORueUYyEAibcEuigksbFMo1392	rogid:zeyNRbcgqPcHXkqwE42s1e9uEqI9606	intact-crc:63C0D40C43AFD979|rigid:0H8j2qD2F070AETvbkuXVmD4vUE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HLZ2	uniprotkb:Q9Y6Q9	intact:EBI-2822704|uniprotkb:Q6I1V2|uniprotkb:Q6KVP4|uniprotkb:E9QXG7|uniprotkb:E9QXG8|uniprotkb:Q81TM2|uniprotkb:A0A0F7RFK1	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066.3|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	psi-mi:a0a6l7hlz2_bacan(display_long)|uniprotkb:GBAA_1249(locus name)	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829215|imex:IM-13779-3277	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006221(Glutamine amidotransferase of anthranilate synthase)|interpro:IPR017926|interpro:IPR029062|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004049""(anthranilate synthase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006541""(glutamine metabolic process)|refseq:WP_000636353.1|interpro:IPR050472"	"refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151.19(gene)|ensembl:ENST00000371998.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035624""(receptor transactivation)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043697""(cell dedifferentiation)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070561""(vitamin D receptor signaling pathway)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|dip:DIP-30876N|ensembl:ENST00000371997.3|ensembl:ENSP00000361065.3|ensembl:ENSP00000361066.3|ensembl:ENST00000372004.7|ensembl:ENSP00000361073.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/12	rogid:VEw7iORueUYyEAibcEuigksbFMo1392	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	intact-crc:03117AFEB5273C6F|rigid:a3pOZjddJEa4TUHpojBi7U7wnH8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6Q9	uniprotkb:Q81LD0	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066.3|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	intact:EBI-2809803|uniprotkb:Q6KM26|uniprotkb:Q6HST3	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:gsa2_bacan(display_long)|uniprotkb:hemL2(gene name)|psi-mi:hemL2(display_short)|uniprotkb:Glutamate-1-semialdehyde aminotransferase 2(gene name synonym)|uniprotkb:BA_4693(locus name)|uniprotkb:GBAA_4693(locus name)|uniprotkb:BAS4358(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829208|imex:IM-13779-3279	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151.19(gene)|ensembl:ENST00000371998.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035624""(receptor transactivation)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043697""(cell dedifferentiation)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045618""(positive regulation of keratinocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070561""(vitamin D receptor signaling pathway)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|dip:DIP-30876N|ensembl:ENST00000371997.3|ensembl:ENSP00000361065.3|ensembl:ENSP00000361066.3|ensembl:ENST00000372004.7|ensembl:ENSP00000361073.1"	"interpro:IPR004639(Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|rcsb pdb:3K28|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0042286""(glutamate-1-semialdehyde 2,1-aminomutase activity)|refseq:WP_001224513.1|refseq:NP_846906.1|refseq:YP_030605.1|interpro:IPR049704"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/12	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	rogid:GnZPBZpKvZpcwazgpwseq6iVQbg1392	intact-crc:1ACAB0795F437FBC|rigid:trjG+qio/JufQbShiTkvKmnKjWg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14686	uniprotkb:A0A6L8PTC5	intact:EBI-78670|uniprotkb:A6NLF1|uniprotkb:Q9NTZ9|uniprotkb:Q9UH74|uniprotkb:Q9UK86|uniprotkb:B2RMN5|uniprotkb:E1P5P7|ensembl:ENSP00000351894.2|ensembl:ENSP00000363929.2	intact:EBI-2829189|uniprotkb:Q6KKN7|uniprotkb:Q6HRB9|uniprotkb:E9R2P3|uniprotkb:E9R2P4|uniprotkb:Q81XI8|uniprotkb:A0A0F7R9Y8	psi-mi:ncoa6_human(display_long)|uniprotkb:NCOA6(gene name)|psi-mi:NCOA6(display_short)|uniprotkb:KIAA0181(gene name synonym)|uniprotkb:RAP250(gene name synonym)|uniprotkb:Amplified in breast cancer protein 3(gene name synonym)|uniprotkb:Cancer-amplified transcriptional coactivator ASC-2(gene name synonym)|uniprotkb:Activating signal cointegrator 2(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor-activating protein, 250 kDa(gene name synonym)|uniprotkb:Nuclear receptor coactivator RAP250(gene name synonym)|uniprotkb:Thyroid hormone receptor-binding protein(gene name synonym)|uniprotkb:AIB3(gene name synonym)|uniprotkb:TRBP(gene name synonym)	psi-mi:a0a6l8ptc5_bacan(display_long)|uniprotkb:GBAA_5249(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829194|imex:IM-13779-3276	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001229468.1|refseq:NP_054790.2|panther:PTHR15690(orthology-group)|refseq:NP_001305169.1|dip:DIP-30934N|ensembl:ENSG00000198646.14(gene)|ensembl:ENST00000359003.7(transcript)|ensembl:ENST00000374796.6(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0006974""(DNA damage response)|go:""GO:0007420""(brain development)|go:""GO:0007507""(heart development)|go:""GO:0009725""(response to hormone)|go:""GO:0019899""(enzyme binding)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|interpro:IPR026638|interpro:IPR032715|mint:Q14686|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922"	"interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR001753(Crotonase, core)|interpro:IPR029045|refseq:WP_000486389.1|go:""GO:0003857""(3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0070403""(NAD+ binding)|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/10	rogid:0PZz93t/oHYDVeiX+8NqjSlpNRo9606	rogid:utkeLKCWsCvBwF1Qny/A3MsfUl81392	intact-crc:1820D813A8E99FC4|rigid:VPZI1doYu9rVgotf43aMHWyYRv8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13772	uniprotkb:A0A6L7H5N1	intact:EBI-954501|uniprotkb:Q14239|uniprotkb:B4E260|uniprotkb:E9PAV7|uniprotkb:J3KQN8|uniprotkb:A8K8W5|intact:EBI-28971630|ensembl:ENSP00000462943.1|ensembl:ENSP00000463476.1|ensembl:ENSP00000464054.1	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:ncoa4_human(display_long)|uniprotkb:Androgen receptor-associated protein of 70 kDa(gene name synonym)|uniprotkb:Ret-activating protein ELE1(gene name synonym)|uniprotkb:NCOA4(gene name)|psi-mi:NCOA4(display_short)|uniprotkb:ARA70(gene name synonym)|uniprotkb:ELE1(gene name synonym)|uniprotkb:RFG(gene name synonym)|uniprotkb:Androgen receptor coactivator 70 kDa protein(gene name synonym)|uniprotkb:Ferritin cargo receptor NCOA4(gene name synonym)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829201|imex:IM-13779-3278	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:146""|dip:DIP-5957N|ensembl:ENSG00000266412.6(gene)|ensembl:ENST00000581486.6(transcript)|ensembl:ENST00000583565.5(transcript)|ensembl:ENST00000585132.5(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005776""(autophagosome)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0008584""(male gonad development)|go:""GO:0009725""(response to hormone)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0044754""(autolysosome)|go:""GO:0071391""(cellular response to estrogen stimulus)|go:""GO:0071394""(cellular response to testosterone stimulus)|interpro:IPR022174|interpro:IPR039947|rcsb pdb:1T5Z|rcsb pdb:8QU9|reactome:R-HSA-9841922|refseq:NP_001138732.1|refseq:NP_001138733.1|refseq:NP_001138734.1|refseq:NP_001138735.1|refseq:NP_005428.1|panther:PTHR17085(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/NfEP88wxWvTac5UcLWx2WJend89606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:9B1905EE69F7997A|rigid:yWmQPp4C7+qbVexvt2klID4AwiU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15596	uniprotkb:A0A6L7H121	intact:EBI-81236|uniprotkb:Q14CD2|ensembl:ENSP00000399968.2	intact:EBI-2812162|uniprotkb:Q6KPC5|uniprotkb:Q6HV53|uniprotkb:E9QR13|uniprotkb:E9QR14|uniprotkb:Q81XV4|uniprotkb:A0A0F7RA44	psi-mi:ncoa2_human(display_long)|uniprotkb:NCOA2(gene name)|psi-mi:NCOA2(display_short)|uniprotkb:TIF2(gene name synonym)|uniprotkb:Transcriptional intermediary factor 2(gene name synonym)|uniprotkb:BHLHE75(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 75(gene name synonym)|uniprotkb:SRC2(gene name synonym)	psi-mi:a0a6l7h121_bacan(display_long)|uniprotkb:GBAA_3814(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829222|imex:IM-13779-3280	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006531.1|ensembl:ENSG00000140396.13(gene)|ensembl:ENST00000452400.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001162""(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0016604""(nuclear body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0017162""(aryl hydrocarbon receptor binding)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032570""(response to progesterone)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1904017""(cellular response to Thyroglobulin triiodothyronine)|go:""GO:1904179""(positive regulation of adipose tissue development)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028822|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15596|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1M2Z|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1P93|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1UHL|rcsb pdb:1YOK|rcsb pdb:1ZDT|rcsb pdb:1ZDU|rcsb pdb:1ZKY|rcsb pdb:2AO6|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2LDC|rcsb pdb:2P15|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2Q7J|rcsb pdb:2Q7L|rcsb pdb:2YJD|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3A9E|rcsb pdb:3CLD|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E7C|rcsb pdb:3E94|rcsb pdb:3ERD|rcsb pdb:3FUG|rcsb pdb:3GN8|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:3KWY|rcsb pdb:3KYT|rcsb pdb:3L0E|rcsb pdb:3L0J|rcsb pdb:3L0L|rcsb pdb:3O1D|rcsb pdb:3O1E|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3PLZ|rcsb pdb:3Q95|rcsb pdb:3R5M|rcsb pdb:3UP0|rcsb pdb:3UP3|rcsb pdb:4CSJ|rcsb pdb:4DOS|rcsb pdb:4E2J|rcsb pdb:4FHH|rcsb pdb:4FHI|rcsb pdb:4IA1|rcsb pdb:4IA2|rcsb pdb:4IA3|rcsb pdb:4IA7|rcsb pdb:4IQR|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4NIE|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4PLD|rcsb pdb:4PLE|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q0A|rcsb pdb:4Q13|rcsb pdb:4QE8|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4RUO|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:4WG0|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5APH|rcsb pdb:5APJ|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXP|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EC9|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5G3J|rcsb pdb:5G42|rcsb pdb:5G43|rcsb pdb:5G44|rcsb pdb:5G45|rcsb pdb:5G46|rcsb pdb:5G5W|rcsb pdb:5H1E|rcsb pdb:5HYR|rcsb pdb:5I4V|rcsb pdb:5IAW|rcsb pdb:5ICK|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5L11|rcsb pdb:5LGA|rcsb pdb:5LYQ|rcsb pdb:5MK4|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5NI5|rcsb pdb:5NI7|rcsb pdb:5NI8|rcsb pdb:5NIB|rcsb pdb:5Q17|rcsb pdb:5SYZ|rcsb pdb:5T1Z|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5U2D|rcsb pdb:5UAN|rcsb pdb:5VB3|rcsb pdb:5VB5|rcsb pdb:5VB6|rcsb pdb:5VB7|rcsb pdb:5VQK|rcsb pdb:5VQL|rcsb pdb:5WGQ|rcsb pdb:5WZX|rcsb pdb:5XPL|rcsb pdb:5Y1J|rcsb pdb:5Y49|rcsb pdb:5YP5|rcsb pdb:5YXB|rcsb pdb:5YXD|rcsb pdb:5YXJ|rcsb pdb:5YXL|rcsb pdb:5Z12|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6ESN|rcsb pdb:6HL1|rcsb pdb:6KKB|rcsb pdb:6KKE|rcsb pdb:6KNU|rcsb pdb:6KNV|rcsb pdb:6KNW|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6LIT|rcsb pdb:6OQX|rcsb pdb:6OQY|rcsb pdb:6OR1|rcsb pdb:6R7A|rcsb pdb:6R7J|rcsb pdb:6R7K|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6VC2|rcsb pdb:6VIF|rcsb pdb:7A77|rcsb pdb:7A78|rcsb pdb:7A79|rcsb pdb:7APO|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7BK4|rcsb pdb:7D42|rcsb pdb:7JHD|rcsb pdb:7JYD|rcsb pdb:7JYE|rcsb pdb:7KCO|rcsb pdb:7NEL|rcsb pdb:7NFB|rcsb pdb:7NKE|rcsb pdb:7OFI|rcsb pdb:7OFK|rcsb pdb:7PDQ|rcsb pdb:7PDT|rcsb pdb:7RAE|rcsb pdb:7RAF|rcsb pdb:7RKE|rcsb pdb:7SFO|rcsb pdb:7T2X|rcsb pdb:7TT8|rcsb pdb:7UW2|rcsb pdb:7UW4|rcsb pdb:7VUE|rcsb pdb:7W3P|rcsb pdb:7W3Q|rcsb pdb:7WLX|rcsb pdb:7WMG|rcsb pdb:7WMH|rcsb pdb:7WMJ|rcsb pdb:7WML|rcsb pdb:7WMN|rcsb pdb:7WMO|rcsb pdb:7YMK|rcsb pdb:8C1L|rcsb pdb:8DAF|rcsb pdb:8EV1|rcsb pdb:8EV2|rcsb pdb:8F8M|rcsb pdb:8GL7|rcsb pdb:8P9X|rcsb pdb:8PP0|rcsb pdb:8PWD|rcsb pdb:8PWE|rcsb pdb:8PWF|rcsb pdb:8PWM|rcsb pdb:8PZ6|rcsb pdb:8PZ7|rcsb pdb:8PZ8|rcsb pdb:8PZ9|rcsb pdb:8PZB|rcsb pdb:8VKZ|rcsb pdb:9EZ1|rcsb pdb:9EZ2|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5625886|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|refseq:NP_001308642.1|refseq:NP_001308632.1|refseq:NP_001308636.1|refseq:NP_001308640.1|refseq:NP_001308641.1|dip:DIP-5997N"	"interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR050750|interpro:IPR029063|go:""GO:0009307""(DNA restriction-modification system)|go:""GO:0032259""(methylation)|go:""GO:0051719""(""DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates"")|go:""GO:0051720""(""DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates"")|refseq:WP_000286272.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:dZP564B7sZPW/ro5h2CVE2XJJpk9606	rogid:hfAwL7rY7VEKa5dCSgNFS9MoDfw1392	intact-crc:0980E20DCBE14DA2|rigid:hw0a1VngRMgZQWiN7Pl2/lVaqIU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15788	uniprotkb:Q81TT4	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940.5|ensembl:ENSP00000385216.1	intact:EBI-2810319|uniprotkb:Q6KVV5|uniprotkb:Q6I218	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:clpb_bacan(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:BA_1177(locus name)|uniprotkb:GBAA_1177(locus name)|uniprotkb:BAS1090(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829255|imex:IM-13779-3284	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_671756.1|refseq:NP_671766.1|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|ensembl:ENSG00000084676.16(gene)|ensembl:ENST00000348332.8(transcript)|ensembl:ENST00000406961.5(transcript)|go:""GO:0000435""(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0002155""(regulation of thyroid hormone receptor signaling pathway)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007595""(lactation)|go:""GO:0008584""(male gonad development)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0021549""(cerebellum development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021854""(hypothalamus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0032355""(response to estradiol)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0032570""(response to progesterone)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0044849""(estrous cycle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045925""(positive regulation of female receptivity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0060179""(male mating behavior)|go:""GO:0060713""(labyrinthine layer morphogenesis)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1904017""(cellular response to Thyroglobulin triiodothyronine)|go:""GO:1904179""(positive regulation of adipose tissue development)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3P88|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|rcsb pdb:4DQM|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5Q1D|rcsb pdb:5Q1E|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7AOS|rcsb pdb:7B39|rcsb pdb:7BNS|rcsb pdb:7BNU|rcsb pdb:7BO6|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7C6Q|rcsb pdb:7CXF|rcsb pdb:7CXH|rcsb pdb:7CXI|rcsb pdb:7CXJ|rcsb pdb:7CXK|rcsb pdb:7CXL|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|rcsb pdb:7OXZ|rcsb pdb:7OY4|rcsb pdb:7QPI|rcsb pdb:7TRB|rcsb pdb:7WGO|rcsb pdb:7WGP|rcsb pdb:7WGQ|rcsb pdb:7WQQ|rcsb pdb:7XVY|rcsb pdb:7XVZ|rcsb pdb:7XWP|rcsb pdb:7XWQ|rcsb pdb:7XWR|rcsb pdb:7Y8F|rcsb pdb:7Y8G|rcsb pdb:7YFK|rcsb pdb:7ZFG|rcsb pdb:7ZFX|rcsb pdb:8CK5|rcsb pdb:8CKC|rcsb pdb:8F5Y|rcsb pdb:8HUK|rcsb pdb:8HUM|rcsb pdb:8HUP|rcsb pdb:8HUQ|rcsb pdb:8P9W|rcsb pdb:8SVN|rcsb pdb:8SVO|rcsb pdb:8SVP|rcsb pdb:8SVQ|rcsb pdb:8SVR|rcsb pdb:8SVS|rcsb pdb:8SVT|rcsb pdb:8SVU|rcsb pdb:8SVX|rcsb pdb:9EYR|rcsb pdb:9FBF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|reactome:R-HSA-9844594|refseq:NP_003734.3|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|panther:PTHR10684(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR050130|interpro:IPR027417|interpro:IPR028299|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034605""(cellular response to heat)|go:""GO:0042026""(protein refolding)|refseq:WP_000365381.1|interpro:IPR036628|interpro:IPR041546|refseq:NP_843655.1|refseq:YP_027362.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/06	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:RwqOsWdy9S7sYBI7SYTY7Mv0pSE1392	intact-crc:B6C715A5BAA203D7|rigid:gDIb5N734olvh3mhVoErv7OmE34	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15596	uniprotkb:A0A2P0HLN8	intact:EBI-81236|uniprotkb:Q14CD2|ensembl:ENSP00000399968.2	intact:EBI-2810906	psi-mi:ncoa2_human(display_long)|uniprotkb:NCOA2(gene name)|psi-mi:NCOA2(display_short)|uniprotkb:TIF2(gene name synonym)|uniprotkb:Transcriptional intermediary factor 2(gene name synonym)|uniprotkb:BHLHE75(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 75(gene name synonym)|uniprotkb:SRC2(gene name synonym)	psi-mi:a0a2p0hln8_bacan(display_long)|uniprotkb:spo0J(gene name)|psi-mi:spo0J(display_short)|uniprotkb:BA_5729(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829229|imex:IM-13779-3283	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006531.1|ensembl:ENSG00000140396.13(gene)|ensembl:ENST00000452400.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001162""(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0016604""(nuclear body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0017162""(aryl hydrocarbon receptor binding)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032570""(response to progesterone)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1904017""(cellular response to Thyroglobulin triiodothyronine)|go:""GO:1904179""(positive regulation of adipose tissue development)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028822|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15596|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1M2Z|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1P93|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1UHL|rcsb pdb:1YOK|rcsb pdb:1ZDT|rcsb pdb:1ZDU|rcsb pdb:1ZKY|rcsb pdb:2AO6|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2LDC|rcsb pdb:2P15|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2Q7J|rcsb pdb:2Q7L|rcsb pdb:2YJD|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3A9E|rcsb pdb:3CLD|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E7C|rcsb pdb:3E94|rcsb pdb:3ERD|rcsb pdb:3FUG|rcsb pdb:3GN8|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:3KWY|rcsb pdb:3KYT|rcsb pdb:3L0E|rcsb pdb:3L0J|rcsb pdb:3L0L|rcsb pdb:3O1D|rcsb pdb:3O1E|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3PLZ|rcsb pdb:3Q95|rcsb pdb:3R5M|rcsb pdb:3UP0|rcsb pdb:3UP3|rcsb pdb:4CSJ|rcsb pdb:4DOS|rcsb pdb:4E2J|rcsb pdb:4FHH|rcsb pdb:4FHI|rcsb pdb:4IA1|rcsb pdb:4IA2|rcsb pdb:4IA3|rcsb pdb:4IA7|rcsb pdb:4IQR|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4NIE|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4PLD|rcsb pdb:4PLE|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q0A|rcsb pdb:4Q13|rcsb pdb:4QE8|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4RUO|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:4WG0|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5APH|rcsb pdb:5APJ|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXP|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EC9|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5G3J|rcsb pdb:5G42|rcsb pdb:5G43|rcsb pdb:5G44|rcsb pdb:5G45|rcsb pdb:5G46|rcsb pdb:5G5W|rcsb pdb:5H1E|rcsb pdb:5HYR|rcsb pdb:5I4V|rcsb pdb:5IAW|rcsb pdb:5ICK|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5L11|rcsb pdb:5LGA|rcsb pdb:5LYQ|rcsb pdb:5MK4|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5NI5|rcsb pdb:5NI7|rcsb pdb:5NI8|rcsb pdb:5NIB|rcsb pdb:5Q17|rcsb pdb:5SYZ|rcsb pdb:5T1Z|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5U2D|rcsb pdb:5UAN|rcsb pdb:5VB3|rcsb pdb:5VB5|rcsb pdb:5VB6|rcsb pdb:5VB7|rcsb pdb:5VQK|rcsb pdb:5VQL|rcsb pdb:5WGQ|rcsb pdb:5WZX|rcsb pdb:5XPL|rcsb pdb:5Y1J|rcsb pdb:5Y49|rcsb pdb:5YP5|rcsb pdb:5YXB|rcsb pdb:5YXD|rcsb pdb:5YXJ|rcsb pdb:5YXL|rcsb pdb:5Z12|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6ESN|rcsb pdb:6HL1|rcsb pdb:6KKB|rcsb pdb:6KKE|rcsb pdb:6KNU|rcsb pdb:6KNV|rcsb pdb:6KNW|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6LIT|rcsb pdb:6OQX|rcsb pdb:6OQY|rcsb pdb:6OR1|rcsb pdb:6R7A|rcsb pdb:6R7J|rcsb pdb:6R7K|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6VC2|rcsb pdb:6VIF|rcsb pdb:7A77|rcsb pdb:7A78|rcsb pdb:7A79|rcsb pdb:7APO|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7BK4|rcsb pdb:7D42|rcsb pdb:7JHD|rcsb pdb:7JYD|rcsb pdb:7JYE|rcsb pdb:7KCO|rcsb pdb:7NEL|rcsb pdb:7NFB|rcsb pdb:7NKE|rcsb pdb:7OFI|rcsb pdb:7OFK|rcsb pdb:7PDQ|rcsb pdb:7PDT|rcsb pdb:7RAE|rcsb pdb:7RAF|rcsb pdb:7RKE|rcsb pdb:7SFO|rcsb pdb:7T2X|rcsb pdb:7TT8|rcsb pdb:7UW2|rcsb pdb:7UW4|rcsb pdb:7VUE|rcsb pdb:7W3P|rcsb pdb:7W3Q|rcsb pdb:7WLX|rcsb pdb:7WMG|rcsb pdb:7WMH|rcsb pdb:7WMJ|rcsb pdb:7WML|rcsb pdb:7WMN|rcsb pdb:7WMO|rcsb pdb:7YMK|rcsb pdb:8C1L|rcsb pdb:8DAF|rcsb pdb:8EV1|rcsb pdb:8EV2|rcsb pdb:8F8M|rcsb pdb:8GL7|rcsb pdb:8P9X|rcsb pdb:8PP0|rcsb pdb:8PWD|rcsb pdb:8PWE|rcsb pdb:8PWF|rcsb pdb:8PWM|rcsb pdb:8PZ6|rcsb pdb:8PZ7|rcsb pdb:8PZ8|rcsb pdb:8PZ9|rcsb pdb:8PZB|rcsb pdb:8VKZ|rcsb pdb:9EZ1|rcsb pdb:9EZ2|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5625886|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|refseq:NP_001308642.1|refseq:NP_001308632.1|refseq:NP_001308636.1|refseq:NP_001308640.1|refseq:NP_001308641.1|dip:DIP-5997N"	"interpro:IPR050336|interpro:IPR003115(ParB-like nuclease)|interpro:IPR004437(ParB-like partition protein)|interpro:IPR036086|go:""GO:0003677""(DNA binding)|go:""GO:0005694""(chromosome)|go:""GO:0007059""(chromosome segregation)|go:""GO:0045881""(positive regulation of sporulation resulting in formation of a cellular spore)|uniprotkb:A0A2K1VHE8(uniprot-removed-ac)|interpro:IPR041468|refseq:NP_847874.2|refseq:WP_001051841.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:dZP564B7sZPW/ro5h2CVE2XJJpk9606	rogid:yZl0oXOncYOEs5/ejxEfcSQuNoE1392	intact-crc:9863DA973B44D3C7|rigid:sVi8AXsm/vOdwq4wB2K6U0yuga0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15596	uniprotkb:A0A6L7H165	intact:EBI-81236|uniprotkb:Q14CD2|ensembl:ENSP00000399968.2	intact:EBI-2811597|uniprotkb:Q6KPI1|uniprotkb:Q6HVB3|uniprotkb:E9QV35|uniprotkb:E9QV36|uniprotkb:A0A2P0HHN5|uniprotkb:Q81Y15	psi-mi:ncoa2_human(display_long)|uniprotkb:NCOA2(gene name)|psi-mi:NCOA2(display_short)|uniprotkb:TIF2(gene name synonym)|uniprotkb:Transcriptional intermediary factor 2(gene name synonym)|uniprotkb:BHLHE75(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 75(gene name synonym)|uniprotkb:SRC2(gene name synonym)	psi-mi:a0a6l7h165_bacan(display_long)|uniprotkb:GBAA_3744(locus name)|uniprotkb:tkt2(gene name)|psi-mi:tkt2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829236|imex:IM-13779-3281	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006531.1|ensembl:ENSG00000140396.13(gene)|ensembl:ENST00000452400.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001162""(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0016604""(nuclear body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0017162""(aryl hydrocarbon receptor binding)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032570""(response to progesterone)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1904017""(cellular response to Thyroglobulin triiodothyronine)|go:""GO:1904179""(positive regulation of adipose tissue development)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028822|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15596|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1M2Z|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1P93|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1UHL|rcsb pdb:1YOK|rcsb pdb:1ZDT|rcsb pdb:1ZDU|rcsb pdb:1ZKY|rcsb pdb:2AO6|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2LDC|rcsb pdb:2P15|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2Q7J|rcsb pdb:2Q7L|rcsb pdb:2YJD|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3A9E|rcsb pdb:3CLD|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E7C|rcsb pdb:3E94|rcsb pdb:3ERD|rcsb pdb:3FUG|rcsb pdb:3GN8|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:3KWY|rcsb pdb:3KYT|rcsb pdb:3L0E|rcsb pdb:3L0J|rcsb pdb:3L0L|rcsb pdb:3O1D|rcsb pdb:3O1E|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3PLZ|rcsb pdb:3Q95|rcsb pdb:3R5M|rcsb pdb:3UP0|rcsb pdb:3UP3|rcsb pdb:4CSJ|rcsb pdb:4DOS|rcsb pdb:4E2J|rcsb pdb:4FHH|rcsb pdb:4FHI|rcsb pdb:4IA1|rcsb pdb:4IA2|rcsb pdb:4IA3|rcsb pdb:4IA7|rcsb pdb:4IQR|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4NIE|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4PLD|rcsb pdb:4PLE|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q0A|rcsb pdb:4Q13|rcsb pdb:4QE8|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4RUO|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:4WG0|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5APH|rcsb pdb:5APJ|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXP|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EC9|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5G3J|rcsb pdb:5G42|rcsb pdb:5G43|rcsb pdb:5G44|rcsb pdb:5G45|rcsb pdb:5G46|rcsb pdb:5G5W|rcsb pdb:5H1E|rcsb pdb:5HYR|rcsb pdb:5I4V|rcsb pdb:5IAW|rcsb pdb:5ICK|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5L11|rcsb pdb:5LGA|rcsb pdb:5LYQ|rcsb pdb:5MK4|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5NI5|rcsb pdb:5NI7|rcsb pdb:5NI8|rcsb pdb:5NIB|rcsb pdb:5Q17|rcsb pdb:5SYZ|rcsb pdb:5T1Z|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5U2D|rcsb pdb:5UAN|rcsb pdb:5VB3|rcsb pdb:5VB5|rcsb pdb:5VB6|rcsb pdb:5VB7|rcsb pdb:5VQK|rcsb pdb:5VQL|rcsb pdb:5WGQ|rcsb pdb:5WZX|rcsb pdb:5XPL|rcsb pdb:5Y1J|rcsb pdb:5Y49|rcsb pdb:5YP5|rcsb pdb:5YXB|rcsb pdb:5YXD|rcsb pdb:5YXJ|rcsb pdb:5YXL|rcsb pdb:5Z12|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6ESN|rcsb pdb:6HL1|rcsb pdb:6KKB|rcsb pdb:6KKE|rcsb pdb:6KNU|rcsb pdb:6KNV|rcsb pdb:6KNW|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6LIT|rcsb pdb:6OQX|rcsb pdb:6OQY|rcsb pdb:6OR1|rcsb pdb:6R7A|rcsb pdb:6R7J|rcsb pdb:6R7K|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6VC2|rcsb pdb:6VIF|rcsb pdb:7A77|rcsb pdb:7A78|rcsb pdb:7A79|rcsb pdb:7APO|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7BK4|rcsb pdb:7D42|rcsb pdb:7JHD|rcsb pdb:7JYD|rcsb pdb:7JYE|rcsb pdb:7KCO|rcsb pdb:7NEL|rcsb pdb:7NFB|rcsb pdb:7NKE|rcsb pdb:7OFI|rcsb pdb:7OFK|rcsb pdb:7PDQ|rcsb pdb:7PDT|rcsb pdb:7RAE|rcsb pdb:7RAF|rcsb pdb:7RKE|rcsb pdb:7SFO|rcsb pdb:7T2X|rcsb pdb:7TT8|rcsb pdb:7UW2|rcsb pdb:7UW4|rcsb pdb:7VUE|rcsb pdb:7W3P|rcsb pdb:7W3Q|rcsb pdb:7WLX|rcsb pdb:7WMG|rcsb pdb:7WMH|rcsb pdb:7WMJ|rcsb pdb:7WML|rcsb pdb:7WMN|rcsb pdb:7WMO|rcsb pdb:7YMK|rcsb pdb:8C1L|rcsb pdb:8DAF|rcsb pdb:8EV1|rcsb pdb:8EV2|rcsb pdb:8F8M|rcsb pdb:8GL7|rcsb pdb:8P9X|rcsb pdb:8PP0|rcsb pdb:8PWD|rcsb pdb:8PWE|rcsb pdb:8PWF|rcsb pdb:8PWM|rcsb pdb:8PZ6|rcsb pdb:8PZ7|rcsb pdb:8PZ8|rcsb pdb:8PZ9|rcsb pdb:8PZB|rcsb pdb:8VKZ|rcsb pdb:9EZ1|rcsb pdb:9EZ2|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5625886|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|panther:PTHR10684(orthology-group)|refseq:NP_001308642.1|refseq:NP_001308632.1|refseq:NP_001308636.1|refseq:NP_001308640.1|refseq:NP_001308641.1|dip:DIP-5997N"	"interpro:IPR033247|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|rcsb pdb:3M49|interpro:IPR029061|go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|refseq:WP_000019755.1|rcsb pdb:3HYL|interpro:IPR049557"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:dZP564B7sZPW/ro5h2CVE2XJJpk9606	rogid:/3w4Fmuo2N06ZcrbsjphHSbI8do1392	intact-crc:BCB8CDF4DD0EB58C|rigid:U2QLuyyHk2KQyg7X/BaeTJnjN0c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15788	uniprotkb:A0A0F7RE60	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940.5|ensembl:ENSP00000385216.1	intact:EBI-2829246|uniprotkb:Q6KPF9|uniprotkb:Q6HV86|uniprotkb:E9QV39|uniprotkb:E9QV40|uniprotkb:Q81XZ0	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:a0a0f7re60_bacan(display_long)|uniprotkb:GBAA_3774(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829243|imex:IM-13779-3282	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_671756.1|refseq:NP_671766.1|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|ensembl:ENSG00000084676.16(gene)|ensembl:ENST00000348332.8(transcript)|ensembl:ENST00000406961.5(transcript)|go:""GO:0000435""(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0002155""(regulation of thyroid hormone receptor signaling pathway)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007595""(lactation)|go:""GO:0008584""(male gonad development)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0021549""(cerebellum development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021854""(hypothalamus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0032355""(response to estradiol)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0032570""(response to progesterone)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0044849""(estrous cycle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045925""(positive regulation of female receptivity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0060179""(male mating behavior)|go:""GO:0060713""(labyrinthine layer morphogenesis)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1904017""(cellular response to Thyroglobulin triiodothyronine)|go:""GO:1904179""(positive regulation of adipose tissue development)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3P88|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|rcsb pdb:4DQM|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5Q1D|rcsb pdb:5Q1E|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7AOS|rcsb pdb:7B39|rcsb pdb:7BNS|rcsb pdb:7BNU|rcsb pdb:7BO6|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7C6Q|rcsb pdb:7CXF|rcsb pdb:7CXH|rcsb pdb:7CXI|rcsb pdb:7CXJ|rcsb pdb:7CXK|rcsb pdb:7CXL|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|rcsb pdb:7OXZ|rcsb pdb:7OY4|rcsb pdb:7QPI|rcsb pdb:7TRB|rcsb pdb:7WGO|rcsb pdb:7WGP|rcsb pdb:7WGQ|rcsb pdb:7WQQ|rcsb pdb:7XVY|rcsb pdb:7XVZ|rcsb pdb:7XWP|rcsb pdb:7XWQ|rcsb pdb:7XWR|rcsb pdb:7Y8F|rcsb pdb:7Y8G|rcsb pdb:7YFK|rcsb pdb:7ZFG|rcsb pdb:7ZFX|rcsb pdb:8CK5|rcsb pdb:8CKC|rcsb pdb:8F5Y|rcsb pdb:8HUK|rcsb pdb:8HUM|rcsb pdb:8HUP|rcsb pdb:8HUQ|rcsb pdb:8P9W|rcsb pdb:8SVN|rcsb pdb:8SVO|rcsb pdb:8SVP|rcsb pdb:8SVQ|rcsb pdb:8SVR|rcsb pdb:8SVS|rcsb pdb:8SVT|rcsb pdb:8SVU|rcsb pdb:8SVX|rcsb pdb:9EYR|rcsb pdb:9FBF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|reactome:R-HSA-9844594|refseq:NP_003734.3|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|panther:PTHR10684(orthology-group)"	"interpro:IPR016024(Armadillo-type fold)|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/06	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:UmTnZlETQFfZ92eOzmPu42YJ/p81392	intact-crc:2BCAA4783C2C7A04|rigid:rcvWQyIRKCXErD6J2FcGDlKBMZI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16333	uniprotkb:Q81VT8	intact:EBI-389883|uniprotkb:B7Z751|intact:EBI-3448658|uniprotkb:D3DNE3|ensembl:ENSP00000288986.2|ensembl:ENSP00000417273.1	intact:EBI-2811891|uniprotkb:Q6I4U2	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:Cytoplasmic protein NCK1(gene name synonym)|uniprotkb:NCK adapter protein 1(gene name synonym)|uniprotkb:SH2/SH3 adapter protein NCK-alpha(gene name synonym)	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829262|imex:IM-13779-3287	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001177725.1|refseq:NP_006144.1|refseq:NP_001278928.1|ensembl:ENSG00000158092.7(gene)|ensembl:ENST00000288986.6(transcript)|ensembl:ENST00000481752.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007015""(actin filament organization)|go:""GO:0007172""(signal complex assembly)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036493""(positive regulation of translation in response to endoplasmic reticulum stress)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0071074""(eukaryotic initiation factor eIF2 binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903676""(positive regulation of cap-dependent translational initiation)|go:""GO:1903679""(positive regulation of cap-independent translational initiation)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1903912""(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|interpro:IPR051184|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-9833482|reactome:R-HSA-983695|dip:DIP-639N|panther:PTHR19969(orthology-group)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	intact-crc:A653145E354F7F8C|rigid:1+hSob+QtNiBj8E1B61qjnOxG5w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NFP9	uniprotkb:A0A6L7HD79	intact:EBI-723014|uniprotkb:B7Z2H9|uniprotkb:Q9HCM8|uniprotkb:Q9NSU1|uniprotkb:Q9NW98|uniprotkb:Q9Y6J1|uniprotkb:Q5T320|ensembl:ENSP00000383295.3	intact:EBI-2829288|uniprotkb:Q6I3A6|uniprotkb:Q6KX23|uniprotkb:E9R068|uniprotkb:E9R069|uniprotkb:A0A2P0HA17|uniprotkb:Q81V23	psi-mi:nbea_human(display_long)|uniprotkb:Lysosomal-trafficking regulator 2(gene name synonym)|uniprotkb:Protein BCL8B(gene name synonym)|uniprotkb:NBEA(gene name)|psi-mi:NBEA(display_short)|uniprotkb:BCL8B(gene name synonym)|uniprotkb:KIAA1544(gene name synonym)|uniprotkb:LYST2(gene name synonym)	psi-mi:a0a6l7hd79_bacan(display_long)|uniprotkb:GBAA_0681(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829293|imex:IM-13779-3288	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:178469""|ensembl:ENSG00000172915.20(gene)|ensembl:ENST00000400445.8(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008104""(protein localization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR010508(Protein of unknown function DUF1088)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|interpro:IPR046851|interpro:IPR046852|interpro:IPR050865|mint:Q8NFP9|rcsb pdb:1MI1|reactome:R-HSA-112314|reactome:R-HSA-163615|reactome:R-HSA-2122947|reactome:R-HSA-9609736|refseq:NP_001191126.1|refseq:NP_056493.3|panther:PTHR13743(orthology-group)"	"interpro:IPR010432(RDD)|interpro:IPR021192|interpro:IPR006976(VanZ like protein)|refseq:WP_000128032.1|go:""GO:0016020""(membrane)|interpro:IPR053150"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gfO4KOqPksy4F827O5y71CM6zPU9606	rogid:MGSDp8V6zl4Fwm8p977SekHVR2A1392	intact-crc:09FD71B39C39269C|rigid:SsvFtc5TEbWF31uvxnGeoK1v5GM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15788	uniprotkb:A0A6L7HQ87	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940.5|ensembl:ENSP00000385216.1	intact:EBI-2829272|uniprotkb:Q6KKK7|uniprotkb:Q6HR92|uniprotkb:E9R6P8|uniprotkb:E9R6P9|uniprotkb:Q81XF7|uniprotkb:A0A0F7R4Q5	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:a0a6l7hq87_bacan(display_long)|uniprotkb:GBAA_5280(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829269|imex:IM-13779-3285	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_671756.1|refseq:NP_671766.1|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|ensembl:ENSG00000084676.16(gene)|ensembl:ENST00000348332.8(transcript)|ensembl:ENST00000406961.5(transcript)|go:""GO:0000435""(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0002155""(regulation of thyroid hormone receptor signaling pathway)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007595""(lactation)|go:""GO:0008584""(male gonad development)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0021549""(cerebellum development)|go:""GO:0021766""(hippocampus development)|go:""GO:0021854""(hypothalamus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030520""(estrogen receptor signaling pathway)|go:""GO:0032355""(response to estradiol)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0032570""(response to progesterone)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035357""(peroxisome proliferator activated receptor signaling pathway)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0044849""(estrous cycle)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045925""(positive regulation of female receptivity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046965""(nuclear retinoid X receptor binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0050847""(progesterone receptor signaling pathway)|go:""GO:0060179""(male mating behavior)|go:""GO:0060713""(labyrinthine layer morphogenesis)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|go:""GO:1904017""(cellular response to Thyroglobulin triiodothyronine)|go:""GO:1904179""(positive regulation of adipose tissue development)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3P88|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|rcsb pdb:4DQM|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5Q1D|rcsb pdb:5Q1E|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7AOS|rcsb pdb:7B39|rcsb pdb:7BNS|rcsb pdb:7BNU|rcsb pdb:7BO6|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7C6Q|rcsb pdb:7CXF|rcsb pdb:7CXH|rcsb pdb:7CXI|rcsb pdb:7CXJ|rcsb pdb:7CXK|rcsb pdb:7CXL|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|rcsb pdb:7OXZ|rcsb pdb:7OY4|rcsb pdb:7QPI|rcsb pdb:7TRB|rcsb pdb:7WGO|rcsb pdb:7WGP|rcsb pdb:7WGQ|rcsb pdb:7WQQ|rcsb pdb:7XVY|rcsb pdb:7XVZ|rcsb pdb:7XWP|rcsb pdb:7XWQ|rcsb pdb:7XWR|rcsb pdb:7Y8F|rcsb pdb:7Y8G|rcsb pdb:7YFK|rcsb pdb:7ZFG|rcsb pdb:7ZFX|rcsb pdb:8CK5|rcsb pdb:8CKC|rcsb pdb:8F5Y|rcsb pdb:8HUK|rcsb pdb:8HUM|rcsb pdb:8HUP|rcsb pdb:8HUQ|rcsb pdb:8P9W|rcsb pdb:8SVN|rcsb pdb:8SVO|rcsb pdb:8SVP|rcsb pdb:8SVQ|rcsb pdb:8SVR|rcsb pdb:8SVS|rcsb pdb:8SVT|rcsb pdb:8SVU|rcsb pdb:8SVX|rcsb pdb:9EYR|rcsb pdb:9FBF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|reactome:R-HSA-9844594|refseq:NP_003734.3|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|panther:PTHR10684(orthology-group)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:WP_000878459.1|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/06	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:KyoAdIZIwnHvbwwfMSttpqT78oQ1392	intact-crc:95D28B93E417C2F2|rigid:wMdZxVPU9Sr344X33Gkv0j280eI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P16333	uniprotkb:A0A6L8P747	intact:EBI-389883|uniprotkb:B7Z751|intact:EBI-3448658|uniprotkb:D3DNE3|ensembl:ENSP00000288986.2|ensembl:ENSP00000417273.1	intact:EBI-2817814|uniprotkb:Q6KTE7|uniprotkb:Q6HZF8|uniprotkb:E9QSG3|uniprotkb:E9QSG4|uniprotkb:Q81JF3|uniprotkb:A0A1Q4M0N4	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:Cytoplasmic protein NCK1(gene name synonym)|uniprotkb:NCK adapter protein 1(gene name synonym)|uniprotkb:SH2/SH3 adapter protein NCK-alpha(gene name synonym)	psi-mi:a0a6l8p747_bacan(display_long)|uniprotkb:GBAA_2171(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829281|imex:IM-13779-3286	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001177725.1|refseq:NP_006144.1|refseq:NP_001278928.1|ensembl:ENSG00000158092.7(gene)|ensembl:ENST00000288986.6(transcript)|ensembl:ENST00000481752.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000164""(protein phosphatase type 1 complex)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006930""(substrate-dependent cell migration, cell extension)|go:""GO:0007015""(actin filament organization)|go:""GO:0007172""(signal complex assembly)|go:""GO:0008093""(cytoskeletal anchor activity)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0036493""(positive regulation of translation in response to endoplasmic reticulum stress)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042110""(T cell activation)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0071074""(eukaryotic initiation factor eIF2 binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:1902237""(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903676""(positive regulation of cap-dependent translational initiation)|go:""GO:1903679""(positive regulation of cap-independent translational initiation)|go:""GO:1903898""(negative regulation of PERK-mediated unfolded protein response)|go:""GO:1903912""(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|interpro:IPR051184|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-9833482|reactome:R-HSA-983695|dip:DIP-639N|panther:PTHR19969(orthology-group)"	"interpro:IPR016024(Armadillo-type fold)|interpro:IPR014824(NIF system FeS cluster assembly, NifU-like scaffold, N-terminal)|interpro:IPR004155(PBS lyase HEAT-like repeat)|interpro:IPR025989|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016829""(lyase activity)|refseq:WP_000692577.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR036498"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	rogid:YsR6ZqoYDi92S0qkRhcZdI5dzxo1392	intact-crc:58AB84C8241D9742|rigid:VCrhaZOHdlNCmzRX4i0cYaIRQPs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13765	uniprotkb:A0A4Y1W8Y6	intact:EBI-712216|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|intact:EBI-25601473|ensembl:ENSP00000349212.3|ensembl:ENSP00000377469.4|ensembl:ENSP00000446801.1|ensembl:ENSP00000447821.1|ensembl:ENSP00000503345.1|uniprotkb:F8VU71	intact:EBI-2813399|uniprotkb:Q6HVH4|uniprotkb:Q6KPP4|uniprotkb:E9QUV8|uniprotkb:E9QUV9|uniprotkb:Q81Y80|uniprotkb:A0A1S0QS99	psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name)	psi-mi:a0a4y1w8y6_bacan(display_long)|uniprotkb:acnA(gene name)|psi-mi:acnA(display_short)|uniprotkb:GBAA_3677(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829329|imex:IM-13779-3290	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|ensembl:ENSG00000196531.14(gene)|ensembl:ENST00000356769.7(transcript)|ensembl:ENST00000393891.8(transcript)|ensembl:ENST00000546392.6(transcript)|ensembl:ENST00000552540.5(transcript)|ensembl:ENST00000678066.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003231""(cardiac ventricle development)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005854""(nascent polypeptide-associated complex)|go:""GO:0006412""(translation)|go:""GO:0010664""(negative regulation of striated muscle cell apoptotic process)|go:""GO:0015031""(protein transport)|go:""GO:0042060""(wound healing)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048633""(positive regulation of skeletal muscle tissue growth)|go:""GO:0048742""(regulation of skeletal muscle fiber development)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905551""(negative regulation of protein localization to endoplasmic reticulum)|go:""GO:2000138""(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|rcsb pdb:7QWQ|rcsb pdb:7QWR|rcsb pdb:7QWS|rcsb pdb:8P2K|rcsb pdb:9F1B|rcsb pdb:9F1C|rcsb pdb:9F1D|rcsb pdb:9FQ0|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N"	"interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR018136|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|refseq:WP_000238573.1|interpro:IPR044137|go:""GO:0003994""(aconitate hydratase activity)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR036008"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/17	rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606	rogid:BjRGZMzqJACHf93aqPDWNtQ4v6g1392	intact-crc:25F9B2616009C721|rigid:7eM1xVcM+sQpTpQviCGha2zU9Ao	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86UW6	uniprotkb:A0A4Y1W7Z0	intact:EBI-2804583|uniprotkb:Q9NVK2|uniprotkb:Q9P2D4|uniprotkb:A0AVR3|intact:EBI-28972272|ensembl:ENSP00000261435.6	intact:EBI-2818189|uniprotkb:Q6HUT6|uniprotkb:Q6KP17|uniprotkb:E9R0Z0|uniprotkb:E9R0Z1|uniprotkb:Q81WN6|uniprotkb:A0A1S0QUZ7	psi-mi:n4bp2_human(display_long)|uniprotkb:B3BP(gene name synonym)|uniprotkb:KIAA1413(gene name synonym)|uniprotkb:BCL-3-binding protein(gene name synonym)|uniprotkb:N4BP2(gene name)|psi-mi:N4BP2(display_short)	psi-mi:a0a4y1w7z0_bacan(display_long)|uniprotkb:GBAA_3936(locus name)|uniprotkb:dapG2(gene name)|psi-mi:dapG2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829336|imex:IM-13779-3291	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011512020.1|refseq:NP_060647.2|refseq:NP_001305288.1|refseq:XP_016863887.1|ensembl:ENSG00000078177.15(gene)|ensembl:ENST00000261435.11(transcript)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004520""(DNA endonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0046404""(ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity)|interpro:IPR002625(Smr protein/MutS2 C-terminal)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR013899(Region of unknown function DUF1771)|interpro:IPR027417|interpro:IPR036063|interpro:IPR041801|interpro:IPR052772|rcsb pdb:2D9I|rcsb pdb:2VKC|rcsb pdb:3BHB|rcsb pdb:3FAU|panther:PTHR46535(orthology-group)"	"interpro:IPR002912(Amino acid-binding ACT)|refseq:WP_000692470.1|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR005260(Aspartate kinase, monofunctional class)|interpro:IPR001341(Aspartate kinase region)|interpro:IPR018042|interpro:IPR027795|go:""GO:0004072""(aspartate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009088""(threonine biosynthetic process)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|go:""GO:0009090""(homoserine biosynthetic process)|go:""GO:0019877""(diaminopimelate biosynthetic process)|interpro:IPR036393|interpro:IPR045865"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SjG6xFHDSeW//hSDpVlz7DwdtrY9606	rogid:itLUMt2/x8+CbVNo1uxcU/D8VU81392	intact-crc:A7D215A345FDC5AA|rigid:/TsmKvRsqPUkBYIocqU10f+R3ZA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43490	uniprotkb:A0A6L8PBA4	intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553.3|ensembl:ENSP00000390591.2|ensembl:ENSP00000506129.1|ensembl:ENSP00000506540.1|intact:EBI-21359121	intact:EBI-2811481|uniprotkb:Q6HWM6|uniprotkb:Q6KQR8|uniprotkb:E9R9K3|uniprotkb:E9R9K4|uniprotkb:Q81NG1|uniprotkb:A0A0F7RFB0	psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym)	psi-mi:a0a6l8pba4_bacan(display_long)|uniprotkb:GBAA_3236(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829307|imex:IM-13779-3289	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005737.1|refseq:XP_005250157.1|ensembl:ENSG00000105835.13(gene)|ensembl:ENST00000222553.8(transcript)|ensembl:ENST00000424768.2(transcript)|ensembl:ENST00000681255.1(transcript)|ensembl:ENST00000681491.1(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009435""(NAD biosynthetic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0030054""(cell junction)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0034356""(obsolete NAD biosynthesis via nicotinamide riboside salvage pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0047280""(nicotinamide phosphoribosyltransferase activity)|go:""GO:0051770""(obsolete positive regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0070062""(extracellular exosome)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|rcsb pdb:6B76|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|rcsb pdb:7ENQ|rcsb pdb:7PPE|rcsb pdb:7PPF|rcsb pdb:7PPG|rcsb pdb:7PPH|rcsb pdb:7PPI|rcsb pdb:8DSC|rcsb pdb:8DSD|rcsb pdb:8DSE|rcsb pdb:8DSH|rcsb pdb:8DSI|rcsb pdb:8DSM|rcsb pdb:8DTJ|rcsb pdb:8F7L|rcsb pdb:8IVU|rcsb pdb:8TM7|reactome:R-HSA-1368108|reactome:R-HSA-197264|reactome:R-HSA-9768919|dip:DIP-29218N|panther:PTHR43816(orthology-group)"	"interpro:IPR027278|interpro:IPR005966(Pyridoxal phosphate-dependent deaminase)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|go:""GO:0019148""(D-cysteine desulfhydrase activity)|refseq:WP_001046577.1|interpro:IPR036052"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606	rogid:wppwoIBS9yJ6YJCkewhEheENTIg1392	intact-crc:BB3D461F25538C10|rigid:dSNqAQ5zhboQYde+TufFunebqnY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HN76	uniprotkb:P49321	intact:EBI-2823076|uniprotkb:Q6KWW5|uniprotkb:Q6I347|uniprotkb:E9QZ49|uniprotkb:E9QZ50|uniprotkb:Q81UW3	intact:EBI-716205|uniprotkb:Q53GW5|uniprotkb:Q5T625|uniprotkb:Q5T622|uniprotkb:Q96A69|uniprotkb:Q9BTW2|uniprotkb:A8K6H2|uniprotkb:B4DQP3|uniprotkb:F5H3J2|uniprotkb:D3DQ07|intact:EBI-28989159|ensembl:ENSP00000255120.5	psi-mi:a0a6l7hn76_bacan(display_long)|uniprotkb:GBAA_0743(locus name)	psi-mi:nasp_human(display_long)|uniprotkb:NASP(gene name)|psi-mi:NASP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829300|imex:IM-13779-3293	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_000748731.1|interpro:IPR036259"	"refseq:NP_001182122.1|refseq:NP_002473.2|refseq:NP_689511.2|refseq:XP_005270945.1|dip:DIP-47269N|ensembl:ENSG00000132780.17(gene)|ensembl:ENST00000350030.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001824""(blastocyst development)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006335""(DNA replication-dependent chromatin assembly)|go:""GO:0008584""(male gonad development)|go:""GO:0015031""(protein transport)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033574""(response to testosterone)|go:""GO:0034080""(CENP-A containing chromatin assembly)|go:""GO:0042393""(histone binding)|go:""GO:0044877""(protein-containing complex binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019544|interpro:IPR019734|interpro:IPR051730|mint:P49321|rcsb pdb:7V1K|rcsb pdb:7V1L|rcsb pdb:7V1M|rcsb pdb:7V6P|rcsb pdb:7V6Q|panther:PTHR15081(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/17	rogid:/PUSu9Hn/StkfIp/Epqy8e2nPNU1392	rogid:8BOknyp+vOh6NF+fXZPYbbqFbH49606	intact-crc:10A6DED328F4BAEB|rigid:/L4ivYWoJ4tESU/zrWrdEQ6cNxw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NZ90	uniprotkb:Q13765	intact:EBI-2822559|uniprotkb:Q6KRW3|uniprotkb:Q6HXU2|uniprotkb:E9QQP0|uniprotkb:E9QQP1|uniprotkb:Q81PM7|uniprotkb:A0A0F7RHX1	intact:EBI-712216|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|intact:EBI-25601473|ensembl:ENSP00000349212.3|ensembl:ENSP00000377469.4|ensembl:ENSP00000446801.1|ensembl:ENSP00000447821.1|ensembl:ENSP00000503345.1|uniprotkb:F8VU71	psi-mi:a0a6l8nz90_bacan(display_long)|uniprotkb:acoB(gene name)|psi-mi:acoB(display_short)|uniprotkb:GBAA_2775(locus name)	psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829322|imex:IM-13779-3292	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033248|interpro:IPR029061|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|go:""GO:0016491""(oxidoreductase activity)|refseq:WP_000198888.1"	"refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|ensembl:ENSG00000196531.14(gene)|ensembl:ENST00000356769.7(transcript)|ensembl:ENST00000393891.8(transcript)|ensembl:ENST00000546392.6(transcript)|ensembl:ENST00000552540.5(transcript)|ensembl:ENST00000678066.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003231""(cardiac ventricle development)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005854""(nascent polypeptide-associated complex)|go:""GO:0006412""(translation)|go:""GO:0010664""(negative regulation of striated muscle cell apoptotic process)|go:""GO:0015031""(protein transport)|go:""GO:0042060""(wound healing)|go:""GO:0043403""(skeletal muscle tissue regeneration)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048633""(positive regulation of skeletal muscle tissue growth)|go:""GO:0048742""(regulation of skeletal muscle fiber development)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905551""(negative regulation of protein localization to endoplasmic reticulum)|go:""GO:2000138""(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|rcsb pdb:7QWQ|rcsb pdb:7QWR|rcsb pdb:7QWS|rcsb pdb:8P2K|rcsb pdb:9F1B|rcsb pdb:9F1C|rcsb pdb:9F1D|rcsb pdb:9FQ0|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/17	rogid:AJmoQea5oxqVcU8nkiE5DDiFS8w1392	rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606	intact-crc:3F7E46398AF429E2|rigid:lqh/7afp1WkLm0vPAj4FHqJqTcQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81JE2	uniprotkb:Q5VU43	intact:EBI-2821133|uniprotkb:Q6KLF7|uniprotkb:E9R1G8	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360.3|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:q81je2_bacan(display_long)|uniprotkb:GBAA_4940(locus name)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829368|imex:IM-13779-3295	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000888038.1|interpro:IPR002543(Cell divisionFtsK/SpoIIIE)|interpro:IPR018541|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041027|interpro:IPR050206"	"refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|ensembl:ENSG00000178104.22(gene)|ensembl:ENST00000369354.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0007098""(centrosome cycle)|go:""GO:0019899""(enzyme binding)|go:""GO:0030016""(myofibril)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|interpro:IPR052593|mint:Q5VU43|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|panther:PTHR46501(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xy54/FqaGRGCLbxoNbGItu3fa4s1392	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	intact-crc:FD02633947035949|rigid:Vf7XW3iXIe+vvP+l3YzkkJtZilA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WYB5	uniprotkb:A0A6L8PKB6	intact:EBI-948029|uniprotkb:O15087|uniprotkb:Q86Y05|uniprotkb:Q8WU81|uniprotkb:Q9UKW2|uniprotkb:Q9UKW3|uniprotkb:Q9UKX0|ensembl:ENSP00000287239.4|ensembl:ENSP00000486595.1|ensembl:ENSP00000497166.1|ensembl:ENSP00000497352.1|ensembl:ENSP00000497718.1|ensembl:ENSP00000497841.1	intact:EBI-2829343|uniprotkb:Q6KN62|uniprotkb:Q6HTY0|uniprotkb:E9RDB5|uniprotkb:E9RDB6|uniprotkb:Q81MI1|uniprotkb:A0A0F7R8T7	psi-mi:kat6b_human(display_long)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4(gene name synonym)|uniprotkb:Histone acetyltransferase MOZ2(gene name synonym)|uniprotkb:Monocytic leukemia zinc finger protein-related factor(gene name synonym)|uniprotkb:KAT6B(gene name)|psi-mi:KAT6B(display_short)|uniprotkb:MYST4(gene name synonym)|uniprotkb:KIAA0383(gene name synonym)|uniprotkb:MORF(gene name synonym)|uniprotkb:MOZ2(gene name synonym)	psi-mi:a0a6l8pkb6_bacan(display_long)|uniprotkb:ptsI(gene name)|psi-mi:ptsI(display_short)|uniprotkb:Phosphotransferase system, enzyme I(gene name synonym)|uniprotkb:GBAA_4267(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829349|imex:IM-13779-3294	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:3047""|efo:""Orphanet:85201""|ensembl:ENSG00000156650.14(gene)|ensembl:ENSG00000281813.4(gene)|ensembl:ENST00000287239.10(transcript)|ensembl:ENST00000630001.4(transcript)|ensembl:ENST00000647630.1(transcript)|ensembl:ENST00000648605.1(transcript)|ensembl:ENST00000648725.1(transcript)|ensembl:ENST00000649463.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000786""(nucleosome)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010484""(histone H3 acetyltransferase activity)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0050793""(regulation of developmental process)|go:""GO:0061733""(protein-lysine-acetyltransferase activity)|go:""GO:0070776""(MOZ/MORF histone acetyltransferase complex)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:1903706""(regulation of hemopoiesis)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR005818(Histone H1/H5)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR019787|interpro:IPR036388|interpro:IPR036390|interpro:IPR040706|interpro:IPR048589|interpro:IPR050603|mint:Q8WYB5|rcsb pdb:5U2J|rcsb pdb:6OIE|rcsb pdb:8E4V|reactome:R-HSA-3214847|refseq:NP_001243397.1|refseq:NP_001243398.1|refseq:NP_036462.2|refseq:XP_005269721.1|refseq:XP_016871489.1|refseq:XP_016871490.1|refseq:XP_016871491.1|refseq:XP_016871492.1|refseq:XP_016871494.1|refseq:XP_016871495.1|refseq:XP_016871496.1|refseq:XP_016871497.1|panther:PTHR10615(orthology-group)"	"interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR018274|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR023151|interpro:IPR006318(Phosphoenolpyruvate-protein phosphotransferase)|interpro:IPR024692|interpro:IPR008731(Phosphotransferase system, PEP-utilising enzyme, N-terminal)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|refseq:WP_000174231.1|go:""GO:0005737""(cytoplasm)|go:""GO:0008965""(phosphoenolpyruvate-protein phosphotransferase activity)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR040442|interpro:IPR036618|interpro:IPR036637|interpro:IPR050499"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SQZ29f1Wqak9s8f4A1mrKmfToU09606	rogid:M3tiM/aRMEMby3QU2yaZgYHNC5g1392	intact-crc:8148ED596EB30D9A|rigid:Q6u64MRF4FDFDens2a22w0J/ZTw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9K5J5	uniprotkb:P35579	intact:EBI-2814961|uniprotkb:Q81U91|uniprotkb:Q6I2H7|uniprotkb:Q6KWA5|uniprotkb:E9R3G5|uniprotkb:E9R3G6|uniprotkb:E9R3G7|uniprotkb:A0A1J9W7Z9|uniprotkb:A0A6L8PRF2	intact:EBI-350338|uniprotkb:O60805|uniprotkb:Q86T83|intact:EBI-1054343|intact:EBI-25631636|uniprotkb:A8K6E4|uniprotkb:Q60FE2|ensembl:ENSP00000216181.6	psi-mi:q9k5j5_bacan(display_long)|uniprotkb:GBAA_0993(locus name)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829382|imex:IM-13779-3296	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009040(Ferritin-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR008331(Ferritin and Dps)|rcsb pdb:2QQY|go:""GO:0004322""(ferroxidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006880""(obsolete intracellular sequestering of iron ion)|go:""GO:0008199""(ferric iron binding)|go:""GO:0020037""(heme binding)|refseq:WP_000017764.1"	"efo:""Orphanet:182050""|efo:""Orphanet:477742""|efo:""Orphanet:90635""|ensembl:ENSG00000100345.23(gene)|ensembl:ENST00000216181.11(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000212""(meiotic spindle organization)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0001931""(uropod)|go:""GO:0003723""(RNA binding)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005826""(actomyosin contractile ring)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016604""(nuclear body)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030220""(platelet formation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032418""(lysosome localization)|go:""GO:0032506""(cytokinetic process)|go:""GO:0032796""(uropod organization)|go:""GO:0032982""(myosin filament)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042641""(actomyosin)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043531""(ADP binding)|go:""GO:0043534""(blood vessel endothelial cell migration)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051015""(actin filament binding)|go:""GO:0051295""(establishment of meiotic spindle localization)|go:""GO:0060471""(cortical granule exocytosis)|go:""GO:0060473""(cortical granule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097513""(myosin II filament)|go:""GO:1903919""(negative regulation of actin filament severing)|go:""GO:1903923""(positive regulation of protein processing in phagocytic vesicle)|go:""GO:1905684""(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|reactome:R-HSA-9725370|refseq:NP_002464.1|refseq:XP_011528499.1|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|panther:PTHR45615(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:W2fLmWtCEAVCVzcMbdBz7iQAWpI1392	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	intact-crc:79BB93615C6E0F5C|rigid:H75v0MihAw14Ofs9DGfNoW2ejVk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2P0H993	uniprotkb:Q5VU43	intact:EBI-2816776|uniprotkb:Q6KXZ2|uniprotkb:E9RD53|uniprotkb:Q81ZE0	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360.3|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:a0a2p0h993_bacan(display_long)|uniprotkb:ampS(gene name)|psi-mi:ampS(display_short)|uniprotkb:GBAA_0329(locus name)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829375|imex:IM-13779-3297	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000007368.1|interpro:IPR035097|interpro:IPR000787(Peptidase M29, aminopeptidase II)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR052170"	"refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|ensembl:ENSG00000178104.22(gene)|ensembl:ENST00000369354.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0007098""(centrosome cycle)|go:""GO:0019899""(enzyme binding)|go:""GO:0030016""(myofibril)|go:""GO:0030953""(astral microtubule organization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:1903358""(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|interpro:IPR052593|mint:Q5VU43|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N|panther:PTHR46501(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Yk+3r/SzwukQgdOcePwJM663zrY1392	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	intact-crc:9C4EFC4F9C35FB3D|rigid:eC+psgeLlE8DGLq79iWYFSTK8CU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60237	uniprotkb:Q81PE9	intact:EBI-2558026|uniprotkb:B7ZMN6|uniprotkb:Q9HCB7|uniprotkb:Q5VUK2|uniprotkb:Q8N179|uniprotkb:Q9HCB8|uniprotkb:A8MYF5|uniprotkb:Q5T506|uniprotkb:Q2TAI8|uniprotkb:A0A0A0MS24|ensembl:ENSP00000476755.1	intact:EBI-2829356|uniprotkb:Q6KRN8|uniprotkb:Q6HXL3	psi-mi:mypt2_human(display_long)|uniprotkb:PPP1R12B(gene name)|psi-mi:PPP1R12B(display_short)|uniprotkb:MYPT2(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 2(gene name synonym)	psi-mi:pepx_bacan(display_long)|uniprotkb:X-prolyl-dipeptidyl aminopeptidase(gene name synonym)|uniprotkb:BA_2860(locus name)|uniprotkb:GBAA_2860(locus name)|uniprotkb:BAS2667(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829361|imex:IM-13779-3298	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002472.2|refseq:NP_001161330.1|refseq:NP_001184060.1|refseq:NP_115286.1|refseq:NP_115287.1|refseq:NP_001161329.1|refseq:XP_016856841.1|refseq:XP_016856842.1|refseq:XP_016856843.1|refseq:NP_001317958.1|ensembl:ENSG00000077157.23(gene)|ensembl:ENST00000608999.6(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006937""(regulation of muscle contraction)|go:""GO:0007165""(signal transduction)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0017020""(myosin phosphatase regulator activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0031672""(A band)|go:""GO:0048812""(neuron projection morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR031775|interpro:IPR036770|interpro:IPR051226|mint:O60237|reactome:R-HSA-2565942|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|panther:PTHR24179(orthology-group)"	"interpro:IPR005674(CocE/NonD hydrolase)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013736(Peptidase S15/CocE/NonD,  C-terminal)|interpro:IPR008252(Peptidase S15, Lactococcus X-Pro dipeptidyl-peptidase)|interpro:IPR000383(Peptidase S15)|interpro:IPR029058|refseq:WP_000516719.1|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008239""(dipeptidyl-peptidase activity)|refseq:NP_845202.1|refseq:YP_028925.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ykCXwp8fMkCrEkx6fqU5vrnTS549606	rogid:oNJlT+4nq2E/YnufyDH8vuL8bUk1392	intact-crc:FA75F27C9C827E52|rigid:TpXRI0adXsdD00x/WxHCdpwfEwQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PZF0	uniprotkb:Q7Z401	intact:EBI-2829403|uniprotkb:Q6KQA0|uniprotkb:Q6HW45|uniprotkb:E9QXW6|uniprotkb:E9QXW7|uniprotkb:Q81MY1|uniprotkb:A0A0F7RG55	intact:EBI-1046479|uniprotkb:Q14655|uniprotkb:Q86T77|uniprotkb:Q8IVX2|uniprotkb:Q8NB93|ensembl:ENSP00000396830.2|uniprotkb:E7EPL3	psi-mi:a0a6l8pzf0_bacan(display_long)|uniprotkb:GBAA_3438(locus name)	psi-mi:mycpp_human(display_long)|uniprotkb:DENN domain-containing protein 4A(gene name synonym)|uniprotkb:DENND4A(gene name)|psi-mi:DENND4A(display_short)|uniprotkb:IRLB(gene name synonym)|uniprotkb:MYCPBP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829408|imex:IM-13779-3300	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR011032(GroES-like)|refseq:WP_000647246.1|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR036291|interpro:IPR051603"	"refseq:NP_001138295.1|refseq:NP_005839.3|ensembl:ENSG00000174485.16(gene)|ensembl:ENST00000431932.6(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032483""(regulation of Rab protein signal transduction)|interpro:IPR001194(DENN)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023341|interpro:IPR037516|interpro:IPR043153|interpro:IPR051696|mint:Q7Z401|reactome:R-HSA-8876198|refseq:XP_005254178.1|refseq:XP_016877352.1|panther:PTHR12296(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Bcn74jmD2ZfPctZr7ZrlFKN/QAA1392	rogid:mZfgls9XVdT2fGgjJ6y2Q8RumoU9606	intact-crc:1759F034832C81E7|rigid:Me7ZjvSeXFbS4qg2ImHUaXDh06I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35579	uniprotkb:Q81KT8	intact:EBI-350338|uniprotkb:O60805|uniprotkb:Q86T83|intact:EBI-1054343|intact:EBI-25631636|uniprotkb:A8K6E4|uniprotkb:Q60FE2|ensembl:ENSP00000216181.6	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829389|imex:IM-13779-3299	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:182050""|efo:""Orphanet:477742""|efo:""Orphanet:90635""|ensembl:ENSG00000100345.23(gene)|ensembl:ENST00000216181.11(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000212""(meiotic spindle organization)|go:""GO:0001525""(angiogenesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001725""(stress fiber)|go:""GO:0001726""(ruffle)|go:""GO:0001768""(establishment of T cell polarity)|go:""GO:0001772""(immunological synapse)|go:""GO:0001778""(plasma membrane repair)|go:""GO:0001931""(uropod)|go:""GO:0003723""(RNA binding)|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005826""(actomyosin contractile ring)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007520""(myoblast fusion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016604""(nuclear body)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0030220""(platelet formation)|go:""GO:0030224""(monocyte differentiation)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0031252""(cell leading edge)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032418""(lysosome localization)|go:""GO:0032506""(cytokinetic process)|go:""GO:0032796""(uropod organization)|go:""GO:0032982""(myosin filament)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042641""(actomyosin)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0043531""(ADP binding)|go:""GO:0043534""(blood vessel endothelial cell migration)|go:""GO:0045055""(regulated exocytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0050900""(leukocyte migration)|go:""GO:0051015""(actin filament binding)|go:""GO:0051295""(establishment of meiotic spindle localization)|go:""GO:0060471""(cortical granule exocytosis)|go:""GO:0060473""(cortical granule)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0097513""(myosin II filament)|go:""GO:1903919""(negative regulation of actin filament severing)|go:""GO:1903923""(positive regulation of protein processing in phagocytic vesicle)|go:""GO:1905684""(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|reactome:R-HSA-9725370|refseq:NP_002464.1|refseq:XP_011528499.1|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|panther:PTHR45615(orthology-group)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	intact-crc:7FCB67862EA005C9|rigid:g7dUIeKy9+Fb+FSfO5je8po1Vdo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7R5J8	uniprotkb:P35580	intact:EBI-2812974|uniprotkb:Q6HQS9|uniprotkb:Q6KK49|uniprotkb:E9RD58|uniprotkb:E9RD59|uniprotkb:Q81WZ5	intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45|ensembl:ENSP00000269243.4	psi-mi:a0a0f7r5j8_bacan(display_long)|uniprotkb:GBAA_5455(locus name)	psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829396|imex:IM-13779-3302	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008928(Six-hairpin glycosidase-like)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016020""(membrane)|interpro:IPR012341(Six-hairpin glycosidase)"	"refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|interpro:IPR002928(Myosin tail)|ensembl:ENSG00000133026.14(gene)|ensembl:ENST00000269243.8(transcript)|go:""GO:0000146""(microfilament motor activity)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001725""(stress fiber)|go:""GO:0003779""(actin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007155""(cell adhesion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009986""(cell surface)|go:""GO:0016459""(myosin complex)|go:""GO:0016460""(myosin II complex)|go:""GO:0030027""(lamellipodium)|go:""GO:0030048""(actin filament-based movement)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|go:""GO:0030496""(midbody)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0032982""(myosin filament)|go:""GO:0035613""(RNA stem-loop binding)|go:""GO:0042641""(actomyosin)|go:""GO:0043531""(ADP binding)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097513""(myosin II filament)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N|panther:PTHR45615(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:+PDMtv28/iYlpm4G1n4eooFdF0k1392	rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606	intact-crc:FFB87E51C7A9E194|rigid:6+McEwCkizUR7QSDM6CyvigBhJU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P6L1	uniprotkb:O75592	intact:EBI-2809878|uniprotkb:Q6I3Z2|uniprotkb:Q6KXQ4|uniprotkb:E9R1Y7|uniprotkb:E9R1Y8|uniprotkb:Q81Z52|uniprotkb:A0A0F7RMG3	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596.2	psi-mi:a0a6l8p6l1_bacan(display_long)|uniprotkb:GBAA_0421(locus name)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829415|imex:IM-13779-3301	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007197(Radical SAM)|interpro:IPR014866(YfkB-like domain)|interpro:IPR013785(Aldolase-type TIM barrel)|go:""GO:0003824""(catalytic activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR031004|refseq:WP_000156003.1"	"refseq:NP_055872.4|dip:DIP-28142N|ensembl:ENSG00000005810.20(gene)|ensembl:ENST00000544440.7(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030424""(axon)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902667""(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|panther:PTHR45943(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:BSJ0SMeZprDBEfO9AnyN2+GNdiI1392	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:2B340C81721F5680|rigid:ktjUpKwAoctxngJeD8yvpuvk2xs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P747	uniprotkb:O75592	intact:EBI-2817814|uniprotkb:Q6KTE7|uniprotkb:Q6HZF8|uniprotkb:E9QSG3|uniprotkb:E9QSG4|uniprotkb:Q81JF3|uniprotkb:A0A1Q4M0N4	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596.2	psi-mi:a0a6l8p747_bacan(display_long)|uniprotkb:GBAA_2171(locus name)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829422|imex:IM-13779-3303	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016024(Armadillo-type fold)|interpro:IPR014824(NIF system FeS cluster assembly, NifU-like scaffold, N-terminal)|interpro:IPR004155(PBS lyase HEAT-like repeat)|interpro:IPR025989|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016829""(lyase activity)|refseq:WP_000692577.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR036498"	"refseq:NP_055872.4|dip:DIP-28142N|ensembl:ENSG00000005810.20(gene)|ensembl:ENST00000544440.7(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030424""(axon)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902667""(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|panther:PTHR45943(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:YsR6ZqoYDi92S0qkRhcZdI5dzxo1392	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:0821964FADBE29EF|rigid:i9C8ytqWmWwgVtLaZJ76EX+POyw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1WDL3	uniprotkb:O75592	intact:EBI-2822569|uniprotkb:Q6I2U2|uniprotkb:Q6KWM1|uniprotkb:E9R9U1|uniprotkb:E9R9U2|uniprotkb:Q81UL3|uniprotkb:A0A0F7RLQ9	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596.2	psi-mi:a0a4y1wdl3_bacan(display_long)|uniprotkb:GBAA_0855(locus name)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829429|imex:IM-13779-3304	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR018313|go:""GO:0005886""(plasma membrane)|go:""GO:0015276""(ligand-gated monoatomic ion channel activity)|refseq:WP_000732844.1"	"refseq:NP_055872.4|dip:DIP-28142N|ensembl:ENSG00000005810.20(gene)|ensembl:ENST00000544440.7(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008582""(regulation of synaptic assembly at neuromuscular junction)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021785""(branchiomotor neuron axon guidance)|go:""GO:0021952""(central nervous system projection neuron axonogenesis)|go:""GO:0030424""(axon)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050905""(neuromuscular process)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:1902667""(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|panther:PTHR45943(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:Io1G55qV3qC/RS4aSI6QR8evBQ81392	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:EE956B0EAD087055|rigid:TOLkM/Q1WietdzCOdErsnkwrLZg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81ME0	uniprotkb:Q14764	intact:EBI-2813646|uniprotkb:Q6KN28|uniprotkb:Q6HTU1	intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977.5|ensembl:ENSP00000378760.1	psi-mi:deob_bacan(display_long)|uniprotkb:deoB(gene name)|psi-mi:deoB(display_short)|uniprotkb:Phosphodeoxyribomutase(gene name synonym)|uniprotkb:BA_4309(locus name)|uniprotkb:GBAA_4309(locus name)|uniprotkb:BAS3997(locus name)	psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829464|imex:IM-13779-3306	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR010045(Phosphopentomutase)|interpro:IPR006124(Metalloenzyme)|interpro:IPR024052|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006015""(5-phosphoribose 1-diphosphate biosynthetic process)|go:""GO:0006018""(2-deoxyribose 1-phosphate catabolic process)|go:""GO:0008973""(phosphopentomutase activity)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0043094""(metabolic compound salvage)|refseq:WP_001046068.1|refseq:NP_846542.1|refseq:YP_030247.1"	"refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364.19(gene)|ensembl:ENST00000357402.10(transcript)|ensembl:ENST00000395353.5(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0008283""(cell population proliferation)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031953""(negative regulation of protein autophosphorylation)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051028""(mRNA transport)|go:""GO:0061099""(negative regulation of protein tyrosine kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072376""(protein activation cascade)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695|refseq:NP_001280133.1|refseq:NP_001280134.1|panther:PTHR14165(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4rSH7u8wKFseFpqFRuqEYAYDNTo1392	rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606	intact-crc:0C02314F9DC84F57|rigid:mj5+HpJKGrBdj/x5YTSECMs2tUA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20591	uniprotkb:Q81K97	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599.3|ensembl:ENSP00000381601.2|ensembl:ENSP00000392151.2|ensembl:ENSP00000402215.2|ensembl:ENSP00000408498.2|ensembl:ENSP00000410523.2|ensembl:ENSP00000505029.1|ensembl:ENSP00000505047.1|ensembl:ENSP00000505051.1|ensembl:ENSP00000505189.1|ensembl:ENSP00000505457.1|ensembl:ENSP00000505489.1|ensembl:ENSP00000505630.1|ensembl:ENSP00000505657.1|ensembl:ENSP00000505669.1|ensembl:ENSP00000505781.1|ensembl:ENSP00000505874.1|ensembl:ENSP00000506047.1|ensembl:ENSP00000506062.1|ensembl:ENSP00000506183.1|ensembl:ENSP00000506199.1|ensembl:ENSP00000506220.1|ensembl:ENSP00000506270.1|ensembl:ENSP00000506348.1|ensembl:ENSP00000506372.1|ensembl:ENSP00000506395.1|ensembl:ENSP00000506481.1|ensembl:ENSP00000506512.1|ensembl:ENSP00000506690.1|ensembl:ENSP00000506712.1	intact:EBI-2822925|uniprotkb:Q6KL14|uniprotkb:Q6HRP7	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:mene_bacan(display_long)|uniprotkb:menE(gene name)|psi-mi:menE(display_short)|uniprotkb:o-succinylbenzoyl-CoA synthetase(gene name synonym)|uniprotkb:BA_5108(locus name)|uniprotkb:GBAA_5108(locus name)|uniprotkb:BAS4747(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829443|imex:IM-13779-3305	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|ensembl:ENSG00000157601.15(gene)|ensembl:ENST00000398598.8(transcript)|ensembl:ENST00000398600.6(transcript)|ensembl:ENST00000413778.6(transcript)|ensembl:ENST00000417963.6(transcript)|ensembl:ENST00000419044.6(transcript)|ensembl:ENST00000455164.6(transcript)|ensembl:ENST00000679445.1(transcript)|ensembl:ENST00000679464.1(transcript)|ensembl:ENST00000679543.1(transcript)|ensembl:ENST00000679626.1(transcript)|ensembl:ENST00000679705.1(transcript)|ensembl:ENST00000679911.1(transcript)|ensembl:ENST00000680176.1(transcript)|ensembl:ENST00000680182.1(transcript)|ensembl:ENST00000680347.1(transcript)|ensembl:ENST00000680364.1(transcript)|ensembl:ENST00000680536.1(transcript)|ensembl:ENST00000680629.1(transcript)|ensembl:ENST00000680760.1(transcript)|ensembl:ENST00000680776.1(transcript)|ensembl:ENST00000681039.1(transcript)|ensembl:ENST00000681191.1(transcript)|ensembl:ENST00000681266.1(transcript)|ensembl:ENST00000681415.1(transcript)|ensembl:ENST00000681607.1(transcript)|ensembl:ENST00000681671.1(transcript)|ensembl:ENST00000681849.1(transcript)|ensembl:ENST00000681857.1(transcript)|ensembl:ENST00000681867.1(transcript)|ensembl:ENST00000681896.1(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006915""(apoptotic process)|go:""GO:0006952""(defense response)|go:""GO:0007165""(signal transduction)|go:""GO:0008017""(microtubule binding)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034340""(response to type I interferon)|go:""GO:0042802""(identical protein binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051607""(defense response to virus)|go:""GO:0070106""(interleukin-27-mediated signaling pathway)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR045063|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733|refseq:XP_011527870.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|panther:PTHR11566(orthology-group)"	"interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR010192(O-succinylbenzoate-CoA ligase)|interpro:IPR025110|refseq:WP_000449553.1|go:""GO:0005524""(ATP binding)|go:""GO:0008756""(o-succinylbenzoate-CoA ligase activity)|go:""GO:0009234""(menaquinone biosynthetic process)|interpro:IPR042099|interpro:IPR050237|refseq:NP_847294.1|refseq:YP_030991.1|interpro:IPR045851"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	rogid:3/TxyNygK8jLtTSE5V04NYB2SLU1392	intact-crc:BC64D165617A3252|rigid:BhM4MeXHEsrUl7WJRt5PHvFVaK4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PKS7	uniprotkb:P20591	intact:EBI-2809705|uniprotkb:Q6HR58|uniprotkb:Q6KKH5|uniprotkb:E9QWF2|uniprotkb:E9QWF3|uniprotkb:A0A2P0HL14|uniprotkb:Q81XC3	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599.3|ensembl:ENSP00000381601.2|ensembl:ENSP00000392151.2|ensembl:ENSP00000402215.2|ensembl:ENSP00000408498.2|ensembl:ENSP00000410523.2|ensembl:ENSP00000505029.1|ensembl:ENSP00000505047.1|ensembl:ENSP00000505051.1|ensembl:ENSP00000505189.1|ensembl:ENSP00000505457.1|ensembl:ENSP00000505489.1|ensembl:ENSP00000505630.1|ensembl:ENSP00000505657.1|ensembl:ENSP00000505669.1|ensembl:ENSP00000505781.1|ensembl:ENSP00000505874.1|ensembl:ENSP00000506047.1|ensembl:ENSP00000506062.1|ensembl:ENSP00000506183.1|ensembl:ENSP00000506199.1|ensembl:ENSP00000506220.1|ensembl:ENSP00000506270.1|ensembl:ENSP00000506348.1|ensembl:ENSP00000506372.1|ensembl:ENSP00000506395.1|ensembl:ENSP00000506481.1|ensembl:ENSP00000506512.1|ensembl:ENSP00000506690.1|ensembl:ENSP00000506712.1	psi-mi:a0a6l8pks7_bacan(display_long)|uniprotkb:GBAA_5317(locus name)	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829457|imex:IM-13779-3309	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR051310|interpro:IPR025278|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|refseq:WP_000455036.1"	"refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|ensembl:ENSG00000157601.15(gene)|ensembl:ENST00000398598.8(transcript)|ensembl:ENST00000398600.6(transcript)|ensembl:ENST00000413778.6(transcript)|ensembl:ENST00000417963.6(transcript)|ensembl:ENST00000419044.6(transcript)|ensembl:ENST00000455164.6(transcript)|ensembl:ENST00000679445.1(transcript)|ensembl:ENST00000679464.1(transcript)|ensembl:ENST00000679543.1(transcript)|ensembl:ENST00000679626.1(transcript)|ensembl:ENST00000679705.1(transcript)|ensembl:ENST00000679911.1(transcript)|ensembl:ENST00000680176.1(transcript)|ensembl:ENST00000680182.1(transcript)|ensembl:ENST00000680347.1(transcript)|ensembl:ENST00000680364.1(transcript)|ensembl:ENST00000680536.1(transcript)|ensembl:ENST00000680629.1(transcript)|ensembl:ENST00000680760.1(transcript)|ensembl:ENST00000680776.1(transcript)|ensembl:ENST00000681039.1(transcript)|ensembl:ENST00000681191.1(transcript)|ensembl:ENST00000681266.1(transcript)|ensembl:ENST00000681415.1(transcript)|ensembl:ENST00000681607.1(transcript)|ensembl:ENST00000681671.1(transcript)|ensembl:ENST00000681849.1(transcript)|ensembl:ENST00000681857.1(transcript)|ensembl:ENST00000681867.1(transcript)|ensembl:ENST00000681896.1(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006915""(apoptotic process)|go:""GO:0006952""(defense response)|go:""GO:0007165""(signal transduction)|go:""GO:0008017""(microtubule binding)|go:""GO:0009615""(response to virus)|go:""GO:0016020""(membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034340""(response to type I interferon)|go:""GO:0042802""(identical protein binding)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051607""(defense response to virus)|go:""GO:0070106""(interleukin-27-mediated signaling pathway)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR045063|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733|refseq:XP_011527870.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|panther:PTHR11566(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LEAQuRzrOsJwYgZq7QXDmoKrfqM1392	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	intact-crc:5EA1A3D8533C2735|rigid:n4UrVV0Z9xrjl4OV0b6ua0fWPog	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92614	uniprotkb:A0A6L7HM02	intact:EBI-949059|uniprotkb:Q5H9U3|uniprotkb:Q5W9F9|uniprotkb:Q5W9G1|uniprotkb:Q8IXP8|intact:EBI-25627010|uniprotkb:Q5QD01|ensembl:ENSP00000437073.1	intact:EBI-2815245|uniprotkb:Q6I1W3|uniprotkb:Q6KVQ5|uniprotkb:E9R7J6|uniprotkb:E9R7J7|uniprotkb:Q81TN3|uniprotkb:A0A1J9VUS2	psi-mi:my18a_human(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym)|uniprotkb:TIAF1(gene name synonym)	psi-mi:a0a6l7hm02_bacan(display_long)|uniprotkb:GBAA_1238(locus name)|uniprotkb:cotZ2(gene name)|psi-mi:cotZ2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829436|imex:IM-13779-3307	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-46631N|refseq:NP_510880.2|refseq:NP_976063.1|refseq:NP_001333696.1|refseq:NP_001333697.1|ensembl:ENSG00000196535.20(gene)|ensembl:ENST00000527372.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0006259""(DNA metabolic process)|go:""GO:0007030""(Golgi organization)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016460""(myosin II complex)|go:""GO:0016477""(cell migration)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032982""(myosin filament)|go:""GO:0042641""(actomyosin)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043531""(ADP binding)|go:""GO:0048194""(Golgi vesicle budding)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0051015""(actin filament binding)|go:""GO:0090161""(Golgi ribbon formation)|go:""GO:0090164""(asymmetric Golgi ribbon formation)|go:""GO:1903028""(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR020587|interpro:IPR027417|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|interpro:IPR041489|mint:Q92614|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|panther:PTHR45615(orthology-group)"	interpro:IPR019593|refseq:WP_001984481.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:IunEYt79RO62wU6VU2gv16Xb7Lk9606	rogid:mKMjG7fmljsv0pGV5NfsS8epdnw1392	intact-crc:404D14EB43D69AED|rigid:Ht/3xrO/m7wfJqCs0VD+ob228Ik	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PQC3	uniprotkb:Q14764	intact:EBI-2811440|uniprotkb:Q6I444|uniprotkb:Q6KXV4|uniprotkb:E9QQR3|uniprotkb:E9QQR4|uniprotkb:A0A2P0H9A7|uniprotkb:Q81ZA2	intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977.5|ensembl:ENSP00000378760.1	psi-mi:a0a6l8pqc3_bacan(display_long)|uniprotkb:GBAA_0370(locus name)	psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829450|imex:IM-13779-3308	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|refseq:WP_000410216.1"	"refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364.19(gene)|ensembl:ENST00000357402.10(transcript)|ensembl:ENST00000395353.5(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0008283""(cell population proliferation)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0031953""(negative regulation of protein autophosphorylation)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0038127""(ERBB signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051028""(mRNA transport)|go:""GO:0061099""(negative regulation of protein tyrosine kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072376""(protein activation cascade)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695|refseq:NP_001280133.1|refseq:NP_001280134.1|panther:PTHR14165(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+ivfvCodXbxbEMok2GCUbqdVQA01392	rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606	intact-crc:968A50304048D22C|rigid:b6zv5Z0MrvtLME7yL+jfvvtBvHE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:A0A6L7H1G2	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2809927	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829471|imex:IM-13779-3310	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	intact-crc:847C1B961E8322DD|rigid:iDcA2ihJVUALjKTH85uOFNlhwTQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:A0A6L7H5N1	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829496|imex:IM-13779-3312	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:2338E80B6EAE7F7D|rigid:njXmOwA0pByx+Mw7b99Wb6A0Pro	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:A0A4Y1WD28	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2829478|uniprotkb:Q6KKW7|uniprotkb:E9R300|uniprotkb:Q81XS4	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:a0a4y1wd28_bacan(display_long)|uniprotkb:GBAA_5156(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829482|imex:IM-13779-3313	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"interpro:IPR010611(3D)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0009254""(peptidoglycan turnover)|go:""GO:0019867""(outer membrane)|refseq:WP_000920105.1|interpro:IPR036908|interpro:IPR051933"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:Yxb7H7MwxhoOJcz4eRxJ4lLOBFQ1392	intact-crc:7F93CA1E6A07D1B8|rigid:JwVYKZYMxg789BA8u57l+GST5fw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01871	uniprotkb:A0A6L7HH45	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	intact:EBI-2810739|uniprotkb:Q6KQJ9|uniprotkb:Q6HWF0|uniprotkb:E9R0C6|uniprotkb:E9R0C7|uniprotkb:Q81N92|uniprotkb:A0A0F7RF31	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	psi-mi:a0a6l7hh45_bacan(display_long)|uniprotkb:GBAA_3323(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829503|imex:IM-13779-3314	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"interpro:IPR025672|interpro:IPR029101|go:""GO:0016020""(membrane)|refseq:WP_000180324.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	rogid:WHI2kqITIISGoQqFf8Ewpzg/Ms01392	intact-crc:061D71073408820B|rigid:YOojCX+/QcwN9lov8s13ZsBNows	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7RGR8	uniprotkb:P01871	intact:EBI-2813786|uniprotkb:Q6I0X6|uniprotkb:Q6KUT2|uniprotkb:E9R0U4|uniprotkb:E9R0U5|uniprotkb:Q81SP4	intact:EBI-953797|intact:EBI-28974488|uniprotkb:P20769|uniprotkb:A0A075B6N9|uniprotkb:A0A0G2JQL4|uniprotkb:P04220|ensembl:ENSP00000490253.1	psi-mi:a0a0f7rgr8_bacan(display_long)|uniprotkb:GBAA_1602(locus name)	psi-mi:ighm_human(display_long)|uniprotkb:Ig mu chain C region BOT(gene name synonym)|uniprotkb:IGHM(gene name)|psi-mi:IGHM(display_short)|uniprotkb:Ig mu chain C region(gene name synonym)|uniprotkb:Ig mu chain C region GAL(gene name synonym)|uniprotkb:Ig mu chain C region OU(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829489|imex:IM-13779-3311	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005494(Glutathionylspermidine synthase)|interpro:IPR016185(PreATP-grasp-like fold)|go:""GO:0005524""(ATP binding)|go:""GO:0016874""(ligase activity)"	"efo:""Orphanet:33110""|ensembl:ENSG00000211899.10(gene)|ensembl:ENST00000637539.2(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002331""(pre-B cell allelic exclusion)|go:""GO:0003823""(antigen binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0045087""(innate immune response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0071755""(IgM B cell receptor complex)|go:""GO:0071756""(pentameric IgM immunoglobulin complex)|go:""GO:0071757""(hexameric IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01871|rcsb pdb:1HEZ|rcsb pdb:2AGJ|rcsb pdb:2RCJ|rcsb pdb:6KXS|rcsb pdb:7K0C|rcsb pdb:7QDO|rcsb pdb:7WSP|rcsb pdb:7XQ8|rcsb pdb:7XT6|rcsb pdb:7Y09|rcsb pdb:7Y0H|rcsb pdb:7Y0J|rcsb pdb:7YG2|rcsb pdb:7YSG|rcsb pdb:7YTC|rcsb pdb:7YTD|rcsb pdb:8ADY|rcsb pdb:8ADZ|rcsb pdb:8AE0|rcsb pdb:8AE2|rcsb pdb:8AE3|rcsb pdb:8BPF|rcsb pdb:8BPG|rcsb pdb:8GZN|rcsb pdb:8WYR|rcsb pdb:8WYS|reactome:R-HSA-202733|reactome:R-HSA-5690714|reactome:R-HSA-9679191|reactome:R-HSA-983695|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qrz0WsU+l8k0qYkmo/NMm2fD4vo1392	rogid:TvdgvEGkRsp1JDrYqEd3qlVT71k9606	intact-crc:C2054619043F0892|rigid:blQUA6ha/VkSo0RApm5FgY0R9xM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PBR9	uniprotkb:Q9NXD2	intact:EBI-2810701|uniprotkb:Q6I1Q5|uniprotkb:Q6KVJ7|uniprotkb:E9QV27|uniprotkb:E9QV28|uniprotkb:Q81TH2|uniprotkb:A0A1J9UYI5	intact:EBI-2829532|uniprotkb:Q6P4Q6|ensembl:ENSP00000402537.1|ensembl:ENSP00000484437.1	psi-mi:a0a6l8pbr9_bacan(display_long)|uniprotkb:GBAA_1303(locus name)	psi-mi:mtmra_human(display_long)|uniprotkb:MTMR10(gene name)|psi-mi:MTMR10(display_short)|uniprotkb:Inactive phosphatidylinositol 3-phosphatase 10(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829537|imex:IM-13779-3318	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000490297.1	"refseq:NP_060232.2|ensembl:ENSG00000166912.17(gene)|ensembl:ENSG00000277086.3(gene)|ensembl:ENST00000435680.6(transcript)|ensembl:ENST00000621195.3(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022587|interpro:IPR029021|interpro:IPR030564|interpro:IPR030573|interpro:IPR036004|mint:Q9NXD2|reactome:R-HSA-1660516|panther:PTHR10807(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:18Maob9Whgm58MiBzcrlsOjPPVQ1392	rogid:Rmg98bSIwX+Hg6BceOx/Z0NdXJE9606	intact-crc:3049541F7B5F7281|rigid:beybhz79TCB4Lakl0gN0mgsAZ1c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H4W8	uniprotkb:Q9HCI7	intact:EBI-2818766|uniprotkb:Q6KRE7|uniprotkb:Q6HXC7|uniprotkb:E9RC00|uniprotkb:E9RC01|uniprotkb:Q81P54|uniprotkb:A0A0F7RG51	intact:EBI-2560775|uniprotkb:Q8NDB4|uniprotkb:Q9NVS4|uniprotkb:Q0D2P1|ensembl:ENSP00000311827.2|uniprotkb:B4DYL4|uniprotkb:G5E9I1	psi-mi:a0a6l7h4w8_bacan(display_long)|uniprotkb:GBAA_2964(locus name)	psi-mi:msl2_human(display_long)|uniprotkb:MSL2(gene name)|psi-mi:MSL2(display_short)|uniprotkb:KIAA1585(gene name synonym)|uniprotkb:MSL2L1(gene name synonym)|uniprotkb:RNF184(gene name synonym)|uniprotkb:Male-specific lethal 2-like 1(gene name synonym)|uniprotkb:Male-specific lethal-2 homolog 1(gene name synonym)|uniprotkb:RING finger protein 184(gene name synonym)|uniprotkb:Male-specific lethal-2 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829551|imex:IM-13779-3317	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|go:""GO:0016410""(N-acyltransferase activity)|go:""GO:0046677""(response to antibiotic)|refseq:WP_000898754.1"	"refseq:NP_001138889.1|refseq:NP_060603.2|refseq:XP_011511251.1|ensembl:ENSG00000174579.5(gene)|ensembl:ENST00000309993.3(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006974""(DNA damage response)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0072487""(MSL complex)|go:""GO:0140585""(promoter-enhancer loop anchoring activity)|go:""GO:0141054""(histone H2B ubiquitin ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032043|interpro:IPR032049|interpro:IPR033467|interpro:IPR037922|mint:Q9HCI7|rcsb pdb:4B7Y|rcsb pdb:4B86|reactome:R-HSA-3214847|refseq:XP_005247628.1|refseq:XP_006713747.1|panther:PTHR16048(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/J8BsEPWv88iVBcgpi6KZFC5+8o1392	rogid:kJp6Yylwcfca/FBNpVGo7y8pbcE9606	intact-crc:68F88885AF021C44|rigid:ZewmYJfJQxm5MYp+BZRASRX8pA0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NVB0	uniprotkb:O43439	intact:EBI-2811493|uniprotkb:Q6KWL2|uniprotkb:Q6I2T1|uniprotkb:E9R8N8|uniprotkb:E9R8N9|uniprotkb:Q81UK2|uniprotkb:A0A0F7RLK2	intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|ensembl:ENSP00000262653.7|ensembl:ENSP00000364428.2|intact:EBI-28968245	psi-mi:a0a6l8nvb0_bacan(display_long)|uniprotkb:alsS(gene name)|psi-mi:alsS(display_short)|uniprotkb:GBAA_0866(locus name)	psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829544|imex:IM-13779-3316	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012782(Acetolactate synthase, catabolic)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR029035|interpro:IPR029061|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003984""(acetolactate synthase activity)|go:""GO:0005948""(acetolactate synthase complex)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0034077""(butanediol metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_000103511.1|interpro:IPR045229"	"refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|ensembl:ENSG00000078699.22(gene)|ensembl:ENST00000346541.7(transcript)|ensembl:ENST00000375279.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0060575""(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291(""Myeloid transforming gene related protein-1 (MTGR1)"")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:O43439|reactome:R-HSA-9827857|refseq:XP_016883610.1|dip:DIP-38274N|panther:PTHR10379(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rRCMmJc9HuwjVl3UsPYv6jvntSI1392	rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606	intact-crc:075E4BCD8CAD5FA0|rigid:kuUQT3sj2aSnIJUXVeFjhXhdiK4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P457	uniprotkb:Q04900	intact:EBI-2813172|uniprotkb:Q6HS51|uniprotkb:Q6KLF1|uniprotkb:E9R1V4|uniprotkb:E9R1V5|uniprotkb:A0A2P0HJY3|uniprotkb:Q81KP6	intact:EBI-2115896|uniprotkb:Q5JSU6|uniprotkb:E1P5E8|uniprotkb:E1P5E7|uniprotkb:E1P5E9|uniprotkb:B4DQ85|uniprotkb:O95413|uniprotkb:Q9BPV0|uniprotkb:Q9NR26|ensembl:ENSP00000309376.4	psi-mi:a0a6l8p457_bacan(display_long)|uniprotkb:GBAA_4947(locus name)	psi-mi:muc24_human(display_long)|uniprotkb:Endolyn(gene name synonym)|uniprotkb:CD164(gene name)|psi-mi:CD164(display_short)|uniprotkb:Multi-glycosylated core protein 24(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829510|imex:IM-13779-3319	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001031503.1|interpro:IPR008007(Peptidase M42)|interpro:IPR023367|interpro:IPR051464|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)"	"panther:PTHR11337(orthology-group)|efo:""Orphanet:90635""|dip:DIP-43970N|ensembl:ENSG00000135535.17(gene)|ensembl:ENST00000310786.10(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007517""(muscle organ development)|go:""GO:0010008""(endosome membrane)|go:""GO:0030097""(hemopoiesis)|interpro:IPR007947(CD164 related protein)|mint:Q04900|refseq:NP_001135873.1|refseq:NP_001135874.1|refseq:NP_001135875.1|refseq:NP_001135876.1|refseq:NP_001333429.1|refseq:NP_006007.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gc3DYbVKwIN0x2KHiydixpUDIW41392	rogid:RnECOHDDKJ98oN/MPUzPHIwRePs9606	intact-crc:1FACA70439213623|rigid:aI1VKIkin2KeYG5gROx7p293HJo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C0I1	uniprotkb:Q81JW1	intact:EBI-2829520|uniprotkb:Q6PFW3|uniprotkb:Q9NX27|uniprotkb:Q96QU2|uniprotkb:Q69YJ4|ensembl:ENSP00000371577.3	intact:EBI-2816384|uniprotkb:Q6KJT7|uniprotkb:Q6HQG2	psi-mi:mtmrc_human(display_long)|uniprotkb:MTMR12(gene name)|psi-mi:MTMR12(display_short)|uniprotkb:KIAA1682(gene name synonym)|uniprotkb:PIP3AP(gene name synonym)|uniprotkb:Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit(gene name synonym)|uniprotkb:Inactive phosphatidylinositol 3-phosphatase 12(gene name synonym)	psi-mi:pyrg_bacan(display_long)|uniprotkb:pyrG(gene name)|psi-mi:pyrG(display_short)|uniprotkb:ctrA(gene name synonym)|uniprotkb:UTP--ammonia ligase(gene name synonym)|uniprotkb:BA_5583(locus name)|uniprotkb:GBAA_5583(locus name)|uniprotkb:BAS5187(locus name)|uniprotkb:Cytidine 5'-triphosphate synthase(gene name synonym)|uniprotkb:Cytidine triphosphate synthetase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829517|imex:IM-13779-3315	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035536.1|refseq:NP_001281272.1|refseq:NP_001281273.1|ensembl:ENSG00000150712.11(gene)|ensembl:ENST00000382142.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0030017""(sarcomere)|go:""GO:0046856""(phosphatidylinositol dephosphorylation)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022587|interpro:IPR029021|interpro:IPR030564|interpro:IPR030576|mint:Q9C0I1|reactome:R-HSA-1660516|panther:PTHR10807(orthology-group)"	"interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR029062|interpro:IPR027417|go:""GO:0003883""(CTP synthase activity)|go:""GO:0004359""(glutaminase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019856""(pyrimidine nucleobase biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0044210""('de novo' CTP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000170456.1|interpro:IPR033828|refseq:NP_847739.1|refseq:YP_031426.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qd9tvo8NLF+Y6jVs9YnqCeyR6hw9606	rogid:SrGr2YO98Kx1ur7cTIL31MeRXwk1392	intact-crc:749AD23DDF57B311|rigid:8+1h519bHVEy3LTmkMq4daSJmn0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N5Y2	uniprotkb:A0A6L8PX73	intact:EBI-2560796|uniprotkb:Q9Y5Z8|uniprotkb:Q9UG70|uniprotkb:B7Z227|uniprotkb:B4DUV8|uniprotkb:A6NCU2|uniprotkb:A6NHW8|uniprotkb:A8K165|ensembl:ENSP00000312244.4	intact:EBI-2814460|uniprotkb:Q6HTD2|uniprotkb:Q6KMM4|uniprotkb:E9R6D4|uniprotkb:E9R6D5|uniprotkb:Q81LY0|uniprotkb:A0A0J1HYA4	psi-mi:ms3l1_human(display_long)|uniprotkb:MSL3(gene name)|psi-mi:MSL3(display_short)|uniprotkb:MSL3L1(gene name synonym)|uniprotkb:Male-specific lethal-3 protein-like 1(gene name synonym)|uniprotkb:Male-specific lethal-3 homolog 1(gene name synonym)|uniprotkb:Male-specific lethal 3 homolog(gene name synonym)	psi-mi:a0a6l8px73_bacan(display_long)|uniprotkb:GBAA_4479(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829558|imex:IM-13779-3320	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001180199.1|refseq:NP_523352.1|refseq:NP_523353.2|refseq:NP_006791.2|refseq:NP_001269103.1|refseq:XP_005274497.1|ensembl:ENSG00000005302.19(gene)|ensembl:ENST00000312196.10(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0035064""(methylated histone binding)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0072487""(MSL complex)|go:""GO:0140566""(histone reader activity)|interpro:IPR000953(Chromo domain)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR026541|interpro:IPR038217|interpro:IPR053820|mint:Q8N5Y2|rcsb pdb:2Y0N|rcsb pdb:3OA6|rcsb pdb:3OB9|reactome:R-HSA-3214847|dip:DIP-56857N|panther:PTHR10880(orthology-group)"	"interpro:IPR003171(Methylenetetrahydrofolate reductase)|interpro:IPR003726(Homocysteine S-methyltransferase)|interpro:IPR050554|interpro:IPR029041|go:""GO:0004489""(""methylenetetrahydrofolate reductase (NAD(P)H) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0008705""(methionine synthase activity)|go:""GO:0032259""(methylation)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|refseq:WP_000770331.1|interpro:IPR036589"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uZsUcEHPwWI+o+d7aGwhfnxVltA9606	rogid:kwYps3uM+vfuLmFjfNZe8XCRW/U1392	intact-crc:F95D3E272B48F949|rigid:UQdsaXAkOYMQAdMdzvlN6ZdGNZg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q02750	uniprotkb:Q81XR1	intact:EBI-492564|ensembl:ENSP00000302486.5	intact:EBI-2829582|uniprotkb:Q6KKV5|uniprotkb:Q6HRI8	psi-mi:mp2k1_human(display_long)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)|uniprotkb:MAP2K1(gene name)|psi-mi:MAP2K1(display_short)|uniprotkb:MEK1(gene name synonym)|uniprotkb:PRKMK1(gene name synonym)	psi-mi:y5172_bacan(display_long)|uniprotkb:BA_5172(locus name)|uniprotkb:GBAA_5172(locus name)|uniprotkb:BAS4807(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829579|imex:IM-13779-3322	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1340""|efo:""Orphanet:389""|ensembl:ENSG00000169032.11(gene)|ensembl:ENST00000307102.10(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004708""(MAP kinase kinase activity)|go:""GO:0004712""(protein serine/threonine/tyrosine kinase activity)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|go:""GO:0007507""(heart development)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008545""(JUN kinase kinase activity)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014044""(Schwann cell development)|go:""GO:0021697""(cerebellar cortex formation)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0030295""(protein kinase activator activity)|go:""GO:0030878""(thyroid gland development)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042552""(myelination)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044342""(type B pancreatic cell proliferation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048538""(thymus development)|go:""GO:0048679""(regulation of axon regeneration)|go:""GO:0048870""(cell motility)|go:""GO:0050772""(positive regulation of axonogenesis)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060324""(face development)|go:""GO:0060440""(trachea formation)|go:""GO:0060502""(epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0060674""(placenta blood vessel development)|go:""GO:0060711""(labyrinthine layer development)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0090398""(cellular senescence)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903226""(positive regulation of endodermal cell differentiation)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050915|mint:Q02750|rcsb pdb:1S9J|rcsb pdb:2P55|rcsb pdb:3DV3|rcsb pdb:3DY7|rcsb pdb:3E8N|rcsb pdb:3EQB|rcsb pdb:3EQC|rcsb pdb:3EQD|rcsb pdb:3EQF|rcsb pdb:3EQG|rcsb pdb:3EQH|rcsb pdb:3EQI|rcsb pdb:3MBL|rcsb pdb:3ORN|rcsb pdb:3OS3|rcsb pdb:3PP1|rcsb pdb:3SLS|rcsb pdb:3V01|rcsb pdb:3V04|rcsb pdb:3VVH|rcsb pdb:3W8Q|rcsb pdb:3WIG|rcsb pdb:3ZLS|rcsb pdb:3ZLW|rcsb pdb:3ZLX|rcsb pdb:3ZLY|rcsb pdb:3ZM4|rcsb pdb:4AN2|rcsb pdb:4AN3|rcsb pdb:4AN9|rcsb pdb:4ANB|rcsb pdb:4ARK|rcsb pdb:4LMN|rcsb pdb:4MNE|rcsb pdb:4U7Z|rcsb pdb:4U80|rcsb pdb:4U81|rcsb pdb:5BX0|rcsb pdb:5EYM|rcsb pdb:5HZE|rcsb pdb:5YT3|rcsb pdb:6NYB|rcsb pdb:6PP9|rcsb pdb:6Q0J|rcsb pdb:6Q0T|rcsb pdb:6U2G|rcsb pdb:6V2W|rcsb pdb:6X2P|rcsb pdb:6X2S|rcsb pdb:6X2X|rcsb pdb:7B3M|rcsb pdb:7B7R|rcsb pdb:7B94|rcsb pdb:7B9L|rcsb pdb:7F2X|rcsb pdb:7M0T|rcsb pdb:7M0U|rcsb pdb:7M0V|rcsb pdb:7M0W|rcsb pdb:7M0X|rcsb pdb:7M0Y|rcsb pdb:7M0Z|rcsb pdb:7MFD|rcsb pdb:7PQV|rcsb pdb:7UMB|rcsb pdb:7XLP|rcsb pdb:7XNC|rcsb pdb:8CHF|rcsb pdb:8DGS|rcsb pdb:8DGT|rcsb pdb:9AXA|rcsb pdb:9AXC|rcsb pdb:9AXH|rcsb pdb:9AXM|rcsb pdb:9AXX|rcsb pdb:9AXY|rcsb pdb:9AY7|rcsb pdb:9AYA|reactome:R-HSA-110056|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5684264|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|refseq:NP_002746.1|refseq:XP_016877900.1|dip:DIP-201N|panther:PTHR48013(orthology-group)|ensembl:ENSP00000302486.5"	interpro:IPR022916|interpro:IPR009910(Protein of unknown function DUF1450)|refseq:WP_000595026.1|refseq:NP_847355.1|refseq:YP_031050.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:ieBLcDINn9hZFZZEIQ3Ktdf2NF89606	rogid:jjkEEv3edo7Wp9aU9INQn6yhQik1392	intact-crc:D4E23F7239EE8466|rigid:zMyz86GPUvANjY/Xx2xuwspLt0Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11717	uniprotkb:A0A6L7HME0	intact:EBI-1048580|uniprotkb:Q7Z7G9|uniprotkb:Q96PT5|ensembl:ENSP00000349437.1	intact:EBI-2810667|uniprotkb:A0A1Q4M2E8|uniprotkb:Q6I2C8|uniprotkb:Q6KW55|uniprotkb:E9R5K0|uniprotkb:E9R5K1|uniprotkb:Q81U40|uniprotkb:A0A1J9WHI8	psi-mi:mpri_human(display_long)|uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym)|uniprotkb:Insulin-like growth factor II receptor(gene name synonym)|uniprotkb:M6P/IGF2 receptor(gene name synonym)|uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym)|uniprotkb:IGF2R(gene name)|psi-mi:IGF2R(display_short)|uniprotkb:MPRI(gene name synonym)	psi-mi:a0a6l7hme0_bacan(display_long)|uniprotkb:ecsA(gene name)|psi-mi:ecsA(display_short)|uniprotkb:GBAA_1048(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829565|imex:IM-13779-3323	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000867.2|ensembl:ENSG00000197081.16(gene)|ensembl:ENST00000356956.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001889""(liver development)|go:""GO:0001965""(G-protein alpha-subunit binding)|go:""GO:0001972""(retinoic acid binding)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005520""(insulin-like growth factor binding)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005641""(nuclear envelope lumen)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007165""(signal transduction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0009791""(post-embryonic development)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030118""(clathrin coat)|go:""GO:0030133""(transport vesicle)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0031995""(insulin-like growth factor II binding)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0044794""(positive regulation by host of viral process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904772""(response to tetrachloromethane)|go:""GO:1905394""(retromer complex binding)|interpro:IPR000479(Cation-independent mannose-6-phosphate receptor)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|interpro:IPR044865|mint:P11717|rcsb pdb:1E6F|rcsb pdb:1GP0|rcsb pdb:1GP3|rcsb pdb:1GQB|rcsb pdb:1JPL|rcsb pdb:1JWG|rcsb pdb:1LF8|rcsb pdb:2CNJ|rcsb pdb:2L29|rcsb pdb:2L2A|rcsb pdb:2M68|rcsb pdb:2M6T|rcsb pdb:2V5N|rcsb pdb:2V5O|rcsb pdb:2V5P|rcsb pdb:5IEI|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6P8I|rcsb pdb:6V02|rcsb pdb:6Z30|rcsb pdb:6Z31|rcsb pdb:6Z32|rcsb pdb:8AFZ|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-6027N|panther:PTHR15071(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR051782|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_001292599.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:7lkG6WR8MQ/SONiTV/8g1ZTtKTU9606	rogid:TlYld1pe8amcr3avJfCXz721u0I1392	intact-crc:648F0CDAEEF17BF9|rigid:wzgTi6mx/0vDg/ugwoKfnJALYs0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A1T3V920	uniprotkb:P36507	intact:EBI-2829591|uniprotkb:Q6HZN8|uniprotkb:Q6KTM5|uniprotkb:E9QS06|uniprotkb:E9QS07|uniprotkb:Q81RG3|uniprotkb:A0A1J9WE79|uniprotkb:A0A2B6CIN6	intact:EBI-1056930|ensembl:ENSP00000262948.4|intact:EBI-15586042	psi-mi:a0a1t3v920_bacan(display_long)|uniprotkb:GBAA_2084(locus name)	psi-mi:mp2k2_human(display_long)|uniprotkb:MAP2K2(gene name)|psi-mi:MAP2K2(display_short)|uniprotkb:MEK2(gene name synonym)|uniprotkb:MKK2(gene name synonym)|uniprotkb:PRKMK2(gene name synonym)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829596|imex:IM-13779-3324	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003740(Protein of unknown function DUF161)|interpro:IPR019264|refseq:WP_000755132.1|go:""GO:0005886""(plasma membrane)|interpro:IPR015867(Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal)|interpro:IPR051461"	"ensembl:ENSG00000126934.15(gene)|ensembl:ENST00000262948.10(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004708""(MAP kinase kinase activity)|go:""GO:0004712""(protein serine/threonine/tyrosine kinase activity)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007507""(heart development)|go:""GO:0008545""(JUN kinase kinase activity)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014044""(Schwann cell development)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030878""(thyroid gland development)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042552""(myelination)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048538""(thymus development)|go:""GO:0048679""(regulation of axon regeneration)|go:""GO:0050772""(positive regulation of axonogenesis)|go:""GO:0060324""(face development)|go:""GO:0060440""(trachea formation)|go:""GO:0060502""(epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:2000147""(positive regulation of cell motility)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050915|mint:P36507|rcsb pdb:1S9I|rcsb pdb:4H3Q|reactome:R-HSA-112411|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|refseq:NP_109587.1|efo:""Orphanet:1340""|efo:""Orphanet:638""|dip:DIP-29119N|panther:PTHR48013(orthology-group)|ensembl:ENSP00000262948.4"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GNxIzdTj4FVzpcGFp8QznEpyzv81392	rogid:JnGMm7dA0eZgBV4A/n+ZjE8ATq49606	intact-crc:9313BEB83C7AD64C|rigid:yujecRJANT/O8B/5vRR2i7TlNC8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PRR8	uniprotkb:P36507	intact:EBI-2811394|uniprotkb:Q6I2G7|uniprotkb:Q6KW94|uniprotkb:E9R8J0|uniprotkb:E9R8J1|uniprotkb:Q81U80|uniprotkb:A0A0F7RLC1	intact:EBI-1056930|ensembl:ENSP00000262948.4|intact:EBI-15586042	psi-mi:a0a6l8prr8_bacan(display_long)|uniprotkb:GBAA_1004(locus name)	psi-mi:mp2k2_human(display_long)|uniprotkb:MAP2K2(gene name)|psi-mi:MAP2K2(display_short)|uniprotkb:MEK2(gene name synonym)|uniprotkb:MKK2(gene name synonym)|uniprotkb:PRKMK2(gene name synonym)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829572|imex:IM-13779-3321	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020843|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR011032(GroES-like)|go:""GO:0016651""(""oxidoreductase activity, acting on NAD(P)H"")|go:""GO:0070402""(NADPH binding)|refseq:WP_000902291.1|interpro:IPR036291"	"ensembl:ENSG00000126934.15(gene)|ensembl:ENST00000262948.10(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004708""(MAP kinase kinase activity)|go:""GO:0004712""(protein serine/threonine/tyrosine kinase activity)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007507""(heart development)|go:""GO:0008545""(JUN kinase kinase activity)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014044""(Schwann cell development)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030878""(thyroid gland development)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0038133""(ERBB2-ERBB3 signaling pathway)|go:""GO:0042552""(myelination)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048538""(thymus development)|go:""GO:0048679""(regulation of axon regeneration)|go:""GO:0050772""(positive regulation of axonogenesis)|go:""GO:0060324""(face development)|go:""GO:0060440""(trachea formation)|go:""GO:0060502""(epithelial cell proliferation involved in lung morphogenesis)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0090170""(regulation of Golgi inheritance)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:2000147""(positive regulation of cell motility)|go:""GO:2000641""(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR050915|mint:P36507|rcsb pdb:1S9I|rcsb pdb:4H3Q|reactome:R-HSA-112411|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|refseq:NP_109587.1|efo:""Orphanet:1340""|efo:""Orphanet:638""|dip:DIP-29119N|panther:PTHR48013(orthology-group)|ensembl:ENSP00000262948.4"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bJoUAV4WZkl9RHHmLvJxDPIL7Wk1392	rogid:JnGMm7dA0eZgBV4A/n+ZjE8ATq49606	intact-crc:AAE0A5F3D66AE826|rigid:i22bcewhDAlt1GFO7ZGr6CKmGp4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:P26038	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-528768|ensembl:ENSP00000353408.5	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:moes_human(display_long)|uniprotkb:Membrane-organizing extension spike protein(gene name synonym)|uniprotkb:MSN(gene name)|psi-mi:MSN(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829629|imex:IM-13779-3326	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"ensembl:ENSG00000147065.18(gene)|ensembl:ENST00000360270.7(transcript)|go:""GO:0001771""(immunological synapse formation)|go:""GO:0001931""(uropod)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0022612""(gland morphogenesis)|go:""GO:0022614""(membrane to membrane docking)|go:""GO:0030175""(filopodium)|go:""GO:0031143""(pseudopodium)|go:""GO:0031528""(microvillus membrane)|go:""GO:0031982""(vesicle)|go:""GO:0042098""(T cell proliferation)|go:""GO:0045177""(apical part of cell)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0050900""(leukocyte migration)|go:""GO:0061028""(establishment of endothelial barrier)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070489""(T cell aggregation)|go:""GO:0071394""(cellular response to testosterone stimulus)|go:""GO:0071803""(positive regulation of podosome assembly)|go:""GO:0071944""(cell periphery)|go:""GO:0072562""(blood microparticle)|go:""GO:0072678""(T cell migration)|go:""GO:1902115""(regulation of organelle assembly)|go:""GO:1902966""(positive regulation of protein localization to early endosome)|go:""GO:2000401""(regulation of lymphocyte migration)|go:""GO:2000643""(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|interpro:IPR046810|mint:P26038|rcsb pdb:1E5W|rcsb pdb:1EF1|rcsb pdb:1SGH|rcsb pdb:6TXQ|rcsb pdb:6TXS|rcsb pdb:8CIR|rcsb pdb:8CIS|rcsb pdb:8CIT|rcsb pdb:8CIU|reactome:R-HSA-437239|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9725370|refseq:NP_002435.1|dip:DIP-33841N|efo:""Orphanet:504530""|panther:PTHR23281(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:XYzuC8VtaVyNYyZ2G5wVbxyPPww9606	intact-crc:730661ED39BB4E79|rigid:EweLZ/E/WE2/Py7qj+zk0y/X2Uc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NVU5	uniprotkb:Q96BY2	intact:EBI-2829639|uniprotkb:Q6KJI5|uniprotkb:Q6HQ41|uniprotkb:E9QW40|uniprotkb:E9QW41|uniprotkb:Q81JJ8|uniprotkb:A0A0F7R9Z2	intact:EBI-739825|uniprotkb:Q9H833|uniprotkb:Q9HAS1|uniprotkb:B2RDF6|ensembl:ENSP00000298894.4|ensembl:ENSP00000451594.1|ensembl:ENSP00000482284.1|ensembl:ENSP00000486260.1	psi-mi:a0a6l8nvu5_bacan(display_long)|uniprotkb:GBAA_5706(locus name)	psi-mi:moap1_human(display_long)|uniprotkb:MOAP1(gene name)|psi-mi:MOAP1(display_short)|uniprotkb:PNMA4(gene name synonym)|uniprotkb:Paraneoplastic antigen Ma4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829636|imex:IM-13779-3328	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|interpro:IPR004438(Peptidase M3B, oligoendopeptidase F)|interpro:IPR013647(Peptidase M3B, oligopeptidase F, N-terminal)|refseq:WP_000655844.1|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0006518""(peptide metabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR042088|interpro:IPR034009|interpro:IPR045090"	"refseq:NP_071434.2|ensembl:ENSG00000165943.5(gene)|ensembl:ENSG00000278268.2(gene)|ensembl:ENST00000298894.5(transcript)|ensembl:ENST00000556883.1(transcript)|ensembl:ENST00000616515.2(transcript)|ensembl:ENST00000627896.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006914""(autophagy)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0051204""(protein insertion into mitochondrial membrane)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:2000786""(positive regulation of autophagosome assembly)|interpro:IPR026523|interpro:IPR048270|interpro:IPR048271|mint:Q96BY2|rcsb pdb:7LGC|dip:DIP-49959N|panther:PTHR23095(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:1697j7FO5OccUXw/FoqPcqhRXXY1392	rogid:wQSSosC82m35M8s+YamN1i73wi49606	intact-crc:E8577E503571E6B6|rigid:NQfW8xnSzL6Cd87wTl0SdGaeBpM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y605	uniprotkb:A0A6L8P747	intact:EBI-995714|uniprotkb:B3KVT2|uniprotkb:D3DVT3|ensembl:ENSP00000318352.4|ensembl:ENSP00000372024.4|ensembl:ENSP00000422065.1	intact:EBI-2817814|uniprotkb:Q6KTE7|uniprotkb:Q6HZF8|uniprotkb:E9QSG3|uniprotkb:E9QSG4|uniprotkb:Q81JF3|uniprotkb:A0A1Q4M0N4	psi-mi:mofa1_human(display_long)|uniprotkb:PGR1(gene name synonym)|uniprotkb:Protein PGR1(gene name synonym)|uniprotkb:Protein associated with MRG of 14 kDa(gene name synonym)|uniprotkb:MRFAP1(gene name)|psi-mi:MRFAP1(display_short)|uniprotkb:PAM14(gene name synonym)	psi-mi:a0a6l8p747_bacan(display_long)|uniprotkb:GBAA_2171(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829622|imex:IM-13779-3325	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_150638.1|refseq:NP_001258982.1|ensembl:ENSG00000179010.16(gene)|ensembl:ENST00000320912.8(transcript)|ensembl:ENST00000382581.5(transcript)|ensembl:ENST00000507420.1(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR029254|mint:Q9Y605|panther:PTHR31324(orthology-group)"	"interpro:IPR016024(Armadillo-type fold)|interpro:IPR014824(NIF system FeS cluster assembly, NifU-like scaffold, N-terminal)|interpro:IPR004155(PBS lyase HEAT-like repeat)|interpro:IPR025989|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016829""(lyase activity)|refseq:WP_000692577.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR036498"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qsRG2MjlSzgcyuUj0/45kBNrfw89606	rogid:YsR6ZqoYDi92S0qkRhcZdI5dzxo1392	intact-crc:AAE33B489955F8F4|rigid:ETnaZWFAG9KbprYMAMvPMQ9De+I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3U7	uniprotkb:A0A6L7H1G2	intact:EBI-358882|uniprotkb:A5D8U7|uniprotkb:A7E2Y0|uniprotkb:Q86TA2|uniprotkb:Q8N3I5|uniprotkb:Q8NAI0|uniprotkb:Q9UPW1|intact:EBI-2829603|intact:EBI-358896|uniprotkb:Q8NHE2|uniprotkb:B9EGP5|uniprotkb:F8VWA6|uniprotkb:F8W1Z6|intact:EBI-10962461|ensembl:ENSP00000377250.4	intact:EBI-2809927	psi-mi:mon2_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)|uniprotkb:KIAA1040(gene name synonym)|uniprotkb:SF21(gene name synonym)|uniprotkb:Protein SF21(gene name synonym)	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829615|imex:IM-13779-3327	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001265399.1|refseq:NP_001265398.1|refseq:NP_055841.2|ensembl:ENSG00000061987.16(gene)|ensembl:ENST00000393630.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0015031""(protein transport)|go:""GO:0031901""(early endosome membrane)|go:""GO:0070062""(extracellular exosome)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032629|interpro:IPR032691|interpro:IPR032817|mint:Q7Z3U7|refseq:XP_016874530.1|panther:PTHR10663(orthology-group)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pEkENsLrswc7Cb2WTKZfQdESrtQ9606	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	intact-crc:BAC2289E77F2BB29|rigid:YuxHdIPCMkT74ndX9+92z+dq3ds	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P41218	uniprotkb:A0A6L8PBD5	intact:EBI-2829677|ensembl:ENSP00000357123.4	intact:EBI-2829672|uniprotkb:Q6I2M5|uniprotkb:Q6KWF6|uniprotkb:E9QXR4|uniprotkb:E9QXR5|uniprotkb:Q81UE4|uniprotkb:A0A0F7RLM5	psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short)	psi-mi:a0a6l8pbd5_bacan(display_long)|uniprotkb:GBAA_0933(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829669|imex:IM-13779-3330	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002423.1|ensembl:ENSG00000163563.8(gene)|ensembl:ENST00000368141.5(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006968""(cellular defense response)|go:""GO:0006974""(DNA damage response)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040205|mint:P41218|rcsb pdb:2DBG|rcsb pdb:5H7Q|rcsb pdb:5WPZ|rcsb pdb:8I6K|reactome:R-HSA-6798695|panther:PTHR12200(orthology-group)"	interpro:IPR006343(DnaD and phage-associated region)|interpro:IPR034829|refseq:WP_000312068.1|interpro:IPR053162	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606	rogid:zaPwWMNfIORViTxNL4kLO80PqEo1392	intact-crc:DE02B973F83C1A2C|rigid:gOhkUli0AqoogQC4VPI9BMBs1Hg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UBU8	uniprotkb:A0A6L8PMG7	intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|uniprotkb:B7Z6R1|ensembl:ENSP00000331310.5	intact:EBI-2824590|uniprotkb:Q3V877|uniprotkb:Q3V8C1|uniprotkb:E9RAG2|uniprotkb:E9RAG3|uniprotkb:Q81SE5|uniprotkb:A0A1Q4M450	psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name)	psi-mi:a0a6l8pmg7_bacan(display_long)|uniprotkb:GBAA_1715(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829662|imex:IM-13779-3332	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006782.1|refseq:NP_996670.1|panther:PTHR10880(orthology-group)|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787.16(gene)|ensembl:ENST00000331268.9(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000786""(nucleosome)|go:""GO:0003682""(chromatin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0016607""(nuclear speck)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070822""(Sin3-type complex)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000779""(regulation of double-strand break repair)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|rcsb pdb:7S4A|rcsb pdb:8BPA|rcsb pdb:8C60|reactome:R-HSA-3214847|dip:DIP-29017N"	"interpro:IPR006135(Type III secretion exporter)|interpro:IPR029025|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|refseq:WP_001030104.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:28GQifqUMxwR32cneTXH+lpW4gM9606	rogid:sydX5tMY/ttp13JJRuA6iK/ZCM41392	intact-crc:CD806649BFFD0C35|rigid:RH7HIXRPgUkAUgnby2fTn5zUzlA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3P1UFF9	uniprotkb:Q9UBU8	intact:EBI-2814027|uniprotkb:Q6KN66|uniprotkb:E9QY50|uniprotkb:Q81MI5	intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|uniprotkb:B7Z6R1|ensembl:ENSP00000331310.5	psi-mi:a0a3p1uff9_bacan(display_long)|uniprotkb:GBAA_4263(locus name)	psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829655|imex:IM-13779-3329	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000160(GGDEF)|interpro:IPR043128|interpro:IPR050469|go:""GO:0005886""(plasma membrane)|go:""GO:0043709""(cell adhesion involved in single-species biofilm formation)|go:""GO:0052621""(diguanylate cyclase activity)|go:""GO:1902201""(negative regulation of bacterial-type flagellum-dependent cell motility)|refseq:WP_001023204.1|interpro:IPR029787"	"refseq:NP_006782.1|refseq:NP_996670.1|panther:PTHR10880(orthology-group)|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787.16(gene)|ensembl:ENST00000331268.9(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000786""(nucleosome)|go:""GO:0003682""(chromatin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0016607""(nuclear speck)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070822""(Sin3-type complex)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000779""(regulation of double-strand break repair)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|rcsb pdb:7S4A|rcsb pdb:8BPA|rcsb pdb:8C60|reactome:R-HSA-3214847|dip:DIP-29017N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:ZJEBfJEJuaZnJUzYq5L+XHlTiKA1392	rogid:28GQifqUMxwR32cneTXH+lpW4gM9606	intact-crc:FB9D7AD729F96F39|rigid:eL3Igmek2JBcFg07AUzfHdb+KHE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15014	uniprotkb:Q81X31	intact:EBI-399257|uniprotkb:B3KP92|uniprotkb:Q567V0|uniprotkb:Q8J026|uniprotkb:D3DXA5|ensembl:ENSP00000353643.1|ensembl:ENSP00000391969.2|ensembl:ENSP00000410532.1|ensembl:ENSP00000415476.2	intact:EBI-2823476|uniprotkb:Q6KK86|uniprotkb:E9RCY9	psi-mi:mo4l2_human(display_long)|uniprotkb:MORF4L2(gene name)|psi-mi:MORF4L2(display_short)|uniprotkb:KIAA0026(gene name synonym)|uniprotkb:MRGX(gene name synonym)|uniprotkb:MORF-related gene X protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRGX(gene name synonym)|uniprotkb:Protein MSL3-2(gene name synonym)	psi-mi:q81x31_bacan(display_long)|uniprotkb:GBAA_5414(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829648|imex:IM-13779-3333	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001135894.1|refseq:NP_001135895.1|refseq:NP_001135896.1|refseq:NP_001135897.1|refseq:NP_001135898.1|refseq:NP_001135899.1|refseq:NP_001135900.1|refseq:NP_001135901.1|refseq:NP_001135902.1|refseq:NP_001135903.1|refseq:NP_001135904.1|refseq:NP_036418.1|refseq:NP_001135890.1|refseq:NP_001135891.1|refseq:NP_001135892.1|refseq:NP_001135893.1|ensembl:ENSG00000123562.18(gene)|ensembl:ENST00000360458.5(transcript)|ensembl:ENST00000433176.6(transcript)|ensembl:ENST00000441076.7(transcript)|ensembl:ENST00000451301.5(transcript)|go:""GO:0000786""(nucleosome)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006281""(DNA repair)|go:""GO:0006325""(chromatin organization)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051155""(positive regulation of striated muscle cell differentiation)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000779""(regulation of double-strand break repair)|interpro:IPR008676(MRG)|interpro:IPR026541|interpro:IPR038217|mint:Q15014|reactome:R-HSA-3214847|panther:PTHR10880(orthology-group)"	"interpro:IPR029045|interpro:IPR005151(Peptidase S41)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004447(Peptidase S41A, C-terminal protease)|interpro:IPR002477(Peptidoglycan binding-like)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0007165""(signal transduction)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|interpro:IPR055210|interpro:IPR036034|interpro:IPR036365|interpro:IPR036366"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7SlnJWNVhfdzirTHBEseWbJQjyU9606	rogid:plObfwnsvGD6eWNj60FiywaOafE1392	intact-crc:3014B696EA159242|rigid:WmK9o3QdRvxILzXKeJpLoEsuSdY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UBU8	uniprotkb:A0A6L7HDR8	intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|uniprotkb:B7Z6R1|ensembl:ENSP00000331310.5	intact:EBI-2813601|uniprotkb:Q6KMC4|uniprotkb:Q6HT37|uniprotkb:E9QVK2|uniprotkb:E9QVK3|uniprotkb:Q81LM9|uniprotkb:A0A0F7R6G5	psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name)	psi-mi:a0a6l7hdr8_bacan(display_long)|uniprotkb:GBAA_4586(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829685|imex:IM-13779-3331	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006782.1|refseq:NP_996670.1|panther:PTHR10880(orthology-group)|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787.16(gene)|ensembl:ENST00000331268.9(transcript)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000786""(nucleosome)|go:""GO:0003682""(chromatin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0016607""(nuclear speck)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070822""(Sin3-type complex)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000779""(regulation of double-strand break repair)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|rcsb pdb:7S4A|rcsb pdb:8BPA|rcsb pdb:8C60|reactome:R-HSA-3214847|dip:DIP-29017N"	"interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR019774|go:""GO:0005506""(iron ion binding)|go:""GO:0009072""(aromatic amino acid metabolic process)|go:""GO:0016714""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen)|refseq:WP_000163221.1|interpro:IPR036329|interpro:IPR036951"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:28GQifqUMxwR32cneTXH+lpW4gM9606	rogid:UgqbKGjZURf/eUAUwQIMUjWsS6Q1392	intact-crc:98C09AD4A06062C9|rigid:pk/WkUGVspMjXOyt9hDpL0pn9xQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HA71	uniprotkb:P19105	intact:EBI-2824991|uniprotkb:Q6KY27|uniprotkb:Q6I4C5|uniprotkb:E9RB02|uniprotkb:E9RB03|uniprotkb:Q81ZH8|uniprotkb:A0A1S0QXP6|uniprotkb:A0A347ZYA1	intact:EBI-354418|ensembl:ENSP00000217652.3|ensembl:ENSP00000441231.1|ensembl:ENSP00000462171.1|ensembl:ENSP00000463614.1|uniprotkb:Q53X45	"psi-mi:a0a6l7ha71_bacan(display_long)|uniprotkb:purE(gene name)|psi-mi:purE(display_short)|uniprotkb:GBAA_0288(locus name)|uniprotkb:""5-(carboxyamino)imidazole ribonucleotide mutase""(gene name synonym)"	psi-mi:ml12a_human(display_long)|uniprotkb:MYL12A(gene name)|psi-mi:MYL12A(display_short)|uniprotkb:RLC(gene name synonym)|uniprotkb:MLCB(gene name synonym)|uniprotkb:Myosin regulatory light chain 2, nonsarcomeric(gene name synonym)|uniprotkb:Myosin RLC(gene name synonym)|uniprotkb:MLC-2B(gene name synonym)|uniprotkb:MRLC3(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC3(gene name synonym)|uniprotkb:Epididymis secretory protein Li 24(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829699|imex:IM-13779-3337	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:4AY3|rcsb pdb:4AY4|rcsb pdb:4B4K|interpro:IPR024694|interpro:IPR000031(""1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase"")|rcsb pdb:1XMP|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0016829""(lyase activity)|go:""GO:0034023""(""5-(carboxyamino)imidazole ribonucleotide mutase activity"")|refseq:WP_000839367.1|interpro:IPR033747"	"refseq:NP_006462.1|ensembl:ENSG00000101608.13(gene)|ensembl:ENST00000217652.8(transcript)|ensembl:ENST00000536605.1(transcript)|ensembl:ENST00000578611.5(transcript)|ensembl:ENST00000579226.5(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016460""(myosin II complex)|go:""GO:0030018""(Z disc)|go:""GO:0035254""(glutamate receptor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|interpro:IPR050403|mint:P19105|reactome:R-HSA-3928664|reactome:R-HSA-445355|refseq:NP_001289976.1|refseq:NP_001289977.1|refseq:NP_001289978.1|panther:PTHR23049(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kxRMqoCmaaQViup9ICnNo4gdCsg1392	rogid:Q1Uv36YgdA5rMmMOyX5+3rKKho09606	intact-crc:9D417EE4F642805E|rigid:u/qmnrPSLTinRzOXO2GsCoZXUok	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14686	uniprotkb:A0A6L8PQC3	intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067.7	intact:EBI-2811440|uniprotkb:Q6I444|uniprotkb:Q6KXV4|uniprotkb:E9QQR3|uniprotkb:E9QQR4|uniprotkb:A0A2P0H9A7|uniprotkb:Q81ZA2	psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym)	psi-mi:a0a6l8pqc3_bacan(display_long)|uniprotkb:GBAA_0370(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829720|imex:IM-13779-3338	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2322""|efo:""Orphanet:589856""|dip:DIP-37875N|ensembl:ENSG00000167548.18(gene)|ensembl:ENST00000301067.12(transcript)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0001555""(oocyte growth)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032259""(methylation)|go:""GO:0033148""(positive regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0042800""(histone H3K4 methyltransferase activity)|go:""GO:0043627""(response to estrogen)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048477""(oogenesis)|go:""GO:0140945""(histone H3K4 monomethyltransferase activity)|go:""GO:0140999""(histone H3K4 trimethyltransferase activity)|go:""GO:1904837""(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|interpro:IPR046341|interpro:IPR046999|interpro:IPR047000|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|rcsb pdb:8U2Y|rcsb pdb:9ATN|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922|refseq:NP_003473.3|refseq:XP_005269219.1|refseq:XP_006719677.1|panther:PTHR45888(orthology-group)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|refseq:WP_000410216.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606	rogid:+ivfvCodXbxbEMok2GCUbqdVQA01392	intact-crc:5788CE5D766B1AB2|rigid:deCxsfuF5Ikxs/ZTPvnfpiT00hE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NEZ4	uniprotkb:A0A6L7HS72	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189.6	intact:EBI-2813060|uniprotkb:Q6KYR5|uniprotkb:Q6I521|uniprotkb:E9R8F3|uniprotkb:E9R8F4|uniprotkb:Q81W18|uniprotkb:A0A0F7R3D8	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	psi-mi:a0a6l7hs72_bacan(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:GBAA_0019(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829706|imex:IM-13779-3335	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:261652""|dip:DIP-48649N|ensembl:ENSG00000055609.21(gene)|ensembl:ENST00000262189.11(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042054""(histone methyltransferase activity)|go:""GO:0042800""(histone H3K4 methyltransferase activity)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051602""(response to electrical stimulus)|go:""GO:0140945""(histone H3K4 monomethyltransferase activity)|go:""GO:0140999""(histone H3K4 trimethyltransferase activity)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|interpro:IPR046341|interpro:IPR047003|interpro:IPR047004|interpro:IPR047005|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|rcsb pdb:7W6L|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922|refseq:NP_733751.2|panther:PTHR45888(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR050238|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0009360""(DNA polymerase III complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_000121566.1|interpro:IPR045085"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/10	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	rogid:gI03FuFZkZPgqwmAbFmVcuBiRWU1392	intact-crc:72E01C3C1C2EA244|rigid:V/Aztqt9eL6l9nBCxxyEl+jay1M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HQ79	uniprotkb:Q8NEZ4	intact:EBI-2823333|uniprotkb:Q6KWL1|uniprotkb:Q6I2T0|uniprotkb:E9QYN0|uniprotkb:E9QYN1|uniprotkb:Q81UK1|uniprotkb:A0A0F7RMR2	intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189.6	psi-mi:a0a6l7hq79_bacan(display_long)|uniprotkb:alsD(gene name)|psi-mi:alsD(display_short)|uniprotkb:GBAA_0867(locus name)	psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829713|imex:IM-13779-3336	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005128(Alpha-acetolactate decarboxylase)|go:""GO:0045151""(acetoin biosynthetic process)|go:""GO:0047605""(acetolactate decarboxylase activity)|refseq:WP_000215036.1"	"efo:""Orphanet:261652""|dip:DIP-48649N|ensembl:ENSG00000055609.21(gene)|ensembl:ENST00000262189.11(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042054""(histone methyltransferase activity)|go:""GO:0042800""(histone H3K4 methyltransferase activity)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0051602""(response to electrical stimulus)|go:""GO:0140945""(histone H3K4 monomethyltransferase activity)|go:""GO:0140999""(histone H3K4 trimethyltransferase activity)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|interpro:IPR046341|interpro:IPR047003|interpro:IPR047004|interpro:IPR047005|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|rcsb pdb:7W6L|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-9772755|reactome:R-HSA-9818564|reactome:R-HSA-9841922|refseq:NP_733751.2|panther:PTHR45888(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/10	rogid:Wd+wa1hmqDwovSQxb7F50Zottt01392	rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606	intact-crc:350AFFB367BA4F9F|rigid:JcUpbkPW+aEkiSjpzEKu9PsBv3k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VT3	uniprotkb:P41218	intact:EBI-2816582|uniprotkb:Q6KYI3|uniprotkb:Q6I4T7	intact:EBI-2829677|ensembl:ENSP00000357123.4	psi-mi:efg_bacan(display_long)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)|uniprotkb:BA_0107(locus name)|uniprotkb:GBAA_0107(locus name)|uniprotkb:BAS0107(locus name)	psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829692|imex:IM-13779-3334	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR031157|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|refseq:WP_000090364.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|refseq:NP_842675.1|refseq:YP_026393.1|interpro:IPR047872"	"refseq:NP_002423.1|ensembl:ENSG00000163563.8(gene)|ensembl:ENST00000368141.5(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006968""(cellular defense response)|go:""GO:0006974""(DNA damage response)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040205|mint:P41218|rcsb pdb:2DBG|rcsb pdb:5H7Q|rcsb pdb:5WPZ|rcsb pdb:8I6K|reactome:R-HSA-6798695|panther:PTHR12200(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iKao5O7KH1KI6bGoVf+7AT6g3181392	rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606	intact-crc:BD856D35A6B1035B|rigid:5aJUn9RIhJJlVYCcaIvK6M4lMWM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6KNA9	uniprotkb:Q15773	intact:EBI-2812936|uniprotkb:Q6HU26|uniprotkb:Q81MM9	intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630.5|ensembl:ENSP00000403941.1|ensembl:ENSP00000446317.1	psi-mi:mete_bacan(display_long)|uniprotkb:metE(gene name)|psi-mi:metE(display_short)|uniprotkb:Cobalamin-independent methionine synthase(gene name synonym)|uniprotkb:Methionine synthase, vitamin-B12 independent isozyme(gene name synonym)|uniprotkb:BA_4218(locus name)|uniprotkb:GBAA_4218(locus name)|uniprotkb:BAS3912(locus name)	psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829727|imex:IM-13779-3341	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001007635.1|interpro:IPR013215(""Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal"")|interpro:IPR006276(5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase)|interpro:IPR002629(Methionine synthase, vitamin-B12 independent)|go:""GO:0003871""(5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0032259""(methylation)|interpro:IPR038071|refseq:NP_846453.1|refseq:YP_030162.1"	"refseq:NP_005430.1|ensembl:ENSG00000089693.11(gene)|ensembl:ENST00000203630.10(transcript)|ensembl:ENST00000435120.5(transcript)|ensembl:ENST00000539187.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016020""(membrane)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR019376|mint:Q15773|panther:PTHR13105(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:zrEJnY1x7+9Q1u7iaM9JmIvFVAQ1392	rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606	intact-crc:A1D22A99CF68D2A4|rigid:fX2xdkNCM7ddrfCTepeRsty2EX0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PW84	uniprotkb:Q9UHC7	intact:EBI-2810036|uniprotkb:Q6I0D7|uniprotkb:Q6KUA7|uniprotkb:E9QSG5|uniprotkb:E9QSG6|uniprotkb:Q81S56|uniprotkb:A0A0F7RJG7	intact:EBI-373524|uniprotkb:Q6GSF1|uniprotkb:Q9H0G0|uniprotkb:Q9UEZ7|uniprotkb:A4D1T7|uniprotkb:B3KXB4|uniprotkb:Q256Y7|uniprotkb:Q59G11|uniprotkb:Q9UHW2|ensembl:ENSP00000255977.2	psi-mi:a0a6l8pw84_bacan(display_long)|uniprotkb:GBAA_1818(locus name)	psi-mi:mkrn1_human(display_long)|uniprotkb:MKRN1(gene name)|psi-mi:MKRN1(display_short)|uniprotkb:RING finger protein 61(gene name synonym)|uniprotkb:RNF61(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase makorin-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829734|imex:IM-13779-3339	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002901(Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase)|interpro:IPR001119(S-layer homology region)|refseq:WP_000756001.1|interpro:IPR051465|go:""GO:0004040""(amidase activity)|go:""GO:0030115""(S-layer)"	"refseq:NP_001138597.1|refseq:NP_038474.2|refseq:XP_011514299.1|refseq:XP_011514300.1|ensembl:ENSG00000133606.11(gene)|ensembl:ENST00000255977.7(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031644|interpro:IPR036855|interpro:IPR041367|interpro:IPR045072|mint:Q9UHC7|reactome:R-HSA-198323|reactome:R-HSA-8948751|reactome:R-HSA-983168|panther:PTHR11224(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rvtlwru3355qXbTQawe6Hx/9UN01392	rogid:oU5t6f0XORO+6RMyVdR3FqDlh0Y9606	intact-crc:EE55FDB799D89F63|rigid:QAPXyLkRIrtrxdzJyf3dsJcsBcs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IXI1	uniprotkb:A0A6L8PXZ6	intact:EBI-1396563|uniprotkb:Q8NF53|uniprotkb:Q96C13|uniprotkb:Q96S17|uniprotkb:Q9BT60|uniprotkb:Q9H7M8|ensembl:ENSP00000321971.4|uniprotkb:A2IDC2	intact:EBI-2819237|uniprotkb:Q6KLV8|uniprotkb:Q6HSL4|uniprotkb:E9QT75|uniprotkb:E9QT76|uniprotkb:Q81L62|uniprotkb:A0A0F7RCQ4	psi-mi:miro2_human(display_long)|uniprotkb:RHOT2(gene name)|psi-mi:RHOT2(display_short)|uniprotkb:ARHT2(gene name synonym)|uniprotkb:C16orf39(gene name synonym)|uniprotkb:Ras homolog gene family member T2(gene name synonym)	psi-mi:a0a6l8pxz6_bacan(display_long)|uniprotkb:GBAA_4769(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829741|imex:IM-13779-3340	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_620124.1|ensembl:ENSG00000140983.15(gene)|ensembl:ENST00000315082.9(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0016020""(membrane)|go:""GO:0019725""(cellular homeostasis)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0097345""(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|interpro:IPR052266|mint:Q8IXI1|rcsb pdb:5KUT|reactome:R-HSA-9013419|panther:PTHR24072(orthology-group)"	"go:""GO:0016020""(membrane)|refseq:WP_001093288.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E+WoN8aoND+U/YkLBUTecrNbDXg9606	rogid:uVipicNoiFP6Z18dMYATXDZ92aA1392	intact-crc:6A091B6E379F39C2|rigid:3V63SRdV1E5IE4qbBYHTBC8E3qY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PZP2	uniprotkb:Q96T58	intact:EBI-2823785|uniprotkb:Q6KQF3|uniprotkb:Q6HWA2|uniprotkb:E9RDT0|uniprotkb:E9RDT1|uniprotkb:Q81N42|uniprotkb:A0A0F7RBH0	intact:EBI-765739|uniprotkb:Q9UQ01|uniprotkb:Q9Y556|uniprotkb:Q9H9A8|uniprotkb:Q9NWH5|ensembl:ENSP00000364912.3|intact:EBI-28975565	psi-mi:a0a6l8pzp2_bacan(display_long)|uniprotkb:GBAA_3375(locus name)	psi-mi:mint_human(display_long)|uniprotkb:SPEN homolog(gene name synonym)|uniprotkb:SMART/HDAC1-associated repressor protein(gene name synonym)|uniprotkb:KIAA0929(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:SHARP(gene name synonym)|uniprotkb:SPEN(gene name)|psi-mi:SPEN(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829748|imex:IM-13779-3342	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004369(Conserved hypothetical protein CHP00011)|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0006412""(translation)|go:""GO:0016829""(lyase activity)|interpro:IPR036754|refseq:WP_000710875.1"	"efo:""Orphanet:1606""|ensembl:ENSG00000065526.13(gene)|ensembl:ENST00000375759.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034172|interpro:IPR034173|interpro:IPR034174|interpro:IPR034175|interpro:IPR035979|interpro:IPR049093|interpro:IPR049094|interpro:IPR049095|mint:Q96T58|rcsb pdb:1OW1|rcsb pdb:2RT5|rcsb pdb:4P6Q|rcsb pdb:7Z1K|reactome:R-HSA-9013422|refseq:NP_055816.2|dip:DIP-34569N|efo:""Orphanet:662234""|panther:PTHR23189(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:ZmwuC6BH0IuhMiv/tpPrMFEwkos1392	rogid:m7bdkKVATaG4dkFG/BYXRn4jOIk9606	intact-crc:B26404C50CDAB817|rigid:MqN/3TnWA7rogCZc90EqH0SE6EE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43451	uniprotkb:A0A6H3A806	intact:EBI-2829774|uniprotkb:Q86UM5|uniprotkb:Q75ME7|uniprotkb:Q0VAX6|ensembl:ENSP00000417515.2|uniprotkb:E7ER45	intact:EBI-2829785|uniprotkb:Q6HYR7|uniprotkb:Q6KSS1|uniprotkb:E9R751|uniprotkb:E9R752|uniprotkb:Q81QJ9|uniprotkb:A0A0F7RC31	psi-mi:mga_human(display_long)|uniprotkb:MGAM(gene name)|psi-mi:MGAM(display_short)|uniprotkb:MGA(gene name synonym)|uniprotkb:MGAML(gene name synonym)|uniprotkb:Alpha-1,4-glucosidase(gene name synonym)	psi-mi:a0a6h3a806_bacan(display_long)|uniprotkb:GBAA_2425(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829782|imex:IM-13779-3344	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004659.2|ensembl:ENSG00000257335.8(gene)|ensembl:ENST00000475668.6(transcript)|go:""GO:0000025""(maltose catabolic process)|go:""GO:0003824""(catalytic activity)|go:""GO:0004339""(glucan 1,4-alpha-glucosidase activity)|go:""GO:0004558""(alpha-1,4-glucosidase activity)|go:""GO:0004574""(oligo-1,6-glucosidase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005983""(starch catabolic process)|go:""GO:0016160""(amylase activity)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1901027""(dextrin catabolic process)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR000519(P-type trefoil)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017957|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|interpro:IPR044913|interpro:IPR048395|mint:O43451|rcsb pdb:2QLY|rcsb pdb:2QMJ|rcsb pdb:3CTT|rcsb pdb:3L4T|rcsb pdb:3L4U|rcsb pdb:3L4V|rcsb pdb:3L4W|rcsb pdb:3L4X|rcsb pdb:3L4Y|rcsb pdb:3L4Z|rcsb pdb:3TON|rcsb pdb:3TOP|reactome:R-HSA-189085|reactome:R-HSA-6798695|refseq:XP_011514974.1|refseq:XP_011514975.1|refseq:XP_016868261.1|refseq:XP_011514973.1|refseq:XP_006716231.1|refseq:XP_011514972.1|panther:PTHR22762(orthology-group)"	"interpro:IPR006035(Ureohydrolase)|refseq:WP_000054641.1|go:""GO:0008783""(agmatinase activity)|go:""GO:0033389""(putrescine biosynthetic process from arginine, via agmatine)|go:""GO:0046872""(metal ion binding)|interpro:IPR023696"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YHyyyj0ELDf6xmuOts5HJUEpkR89606	rogid:Ywoc8NhkkLXFsRKfxOJmIRGanag1392	intact-crc:794C33EC0405301C|rigid:gNQ2P/+Y+zE8phOdTzf5WZzKV68	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96T58	uniprotkb:A0A6L8PD01	intact:EBI-765739|uniprotkb:Q9UQ01|uniprotkb:Q9Y556|uniprotkb:Q9H9A8|uniprotkb:Q9NWH5|ensembl:ENSP00000364912.3|intact:EBI-28975565	intact:EBI-2810689|uniprotkb:Q6KR00|uniprotkb:Q6HWW8|uniprotkb:E9QQS7|uniprotkb:E9QQS8|uniprotkb:Q81NP8	psi-mi:mint_human(display_long)|uniprotkb:SPEN homolog(gene name synonym)|uniprotkb:SMART/HDAC1-associated repressor protein(gene name synonym)|uniprotkb:KIAA0929(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:SHARP(gene name synonym)|uniprotkb:SPEN(gene name)|psi-mi:SPEN(display_short)	psi-mi:a0a6l8pd01_bacan(display_long)|uniprotkb:GBAA_3131(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829755|imex:IM-13779-3345	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1606""|ensembl:ENSG00000065526.13(gene)|ensembl:ENST00000375759.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034172|interpro:IPR034173|interpro:IPR034174|interpro:IPR034175|interpro:IPR035979|interpro:IPR049093|interpro:IPR049094|interpro:IPR049095|mint:Q96T58|rcsb pdb:1OW1|rcsb pdb:2RT5|rcsb pdb:4P6Q|rcsb pdb:7Z1K|reactome:R-HSA-9013422|refseq:NP_055816.2|dip:DIP-34569N|efo:""Orphanet:662234""|panther:PTHR23189(orthology-group)"	"interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR036291|refseq:WP_000649082.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:m7bdkKVATaG4dkFG/BYXRn4jOIk9606	rogid:zX4+aIdzhDeWoVC9l0OlbVnHVow1392	intact-crc:22035C541A7D09C0|rigid:GupuNU2BVTg0Z04v1HStj/d+ZzM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1WE58	uniprotkb:P16455	intact:EBI-2810305|uniprotkb:Q6KW20|uniprotkb:Q6I285|uniprotkb:E9R1F6|uniprotkb:E9R1F7|uniprotkb:A0A2P0HB60|uniprotkb:Q81U00	intact:EBI-2829762|uniprotkb:Q5VY78|ensembl:ENSP00000498729.1	psi-mi:a0a4y1we58_bacan(display_long)|uniprotkb:GBAA_1094(locus name)	psi-mi:mgmt_human(display_long)|uniprotkb:MGMT(gene name)|psi-mi:MGMT(display_short)|uniprotkb:6-O-methylguanine-DNA methyltransferase(gene name synonym)|uniprotkb:O-6-methylguanine-DNA-alkyltransferase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829767|imex:IM-13779-3343	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020968|interpro:IPR008979(Galactose-binding like)|interpro:IPR022385|interpro:IPR006530(YD repeat)|interpro:IPR050708|go:""GO:0016020""(membrane)|refseq:WP_000387561.1|interpro:IPR045351|interpro:IPR031325"	"efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:618""|ensembl:ENSG00000170430.10(gene)|ensembl:ENST00000651593.1(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003908""(methylated-DNA-[protein]-cysteine S-methyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006266""(obsolete DNA ligation)|go:""GO:0006281""(DNA repair)|go:""GO:0006307""(DNA alkylation repair)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0009008""(DNA-methyltransferase activity)|go:""GO:0016020""(membrane)|go:""GO:0032259""(methylation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046872""(metal ion binding)|go:""GO:2000781""(positive regulation of double-strand break repair)|interpro:IPR001497(Methylated-DNA-[protein]-cysteine S-methyltransferase, active site)|interpro:IPR008332(Methylguanine DNA methyltransferase, ribonuclease-like)|interpro:IPR014048(Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding)|interpro:IPR036217|interpro:IPR036388|interpro:IPR036631|mint:P16455|rcsb pdb:1EH6|rcsb pdb:1EH7|rcsb pdb:1EH8|rcsb pdb:1QNT|rcsb pdb:1T38|rcsb pdb:1T39|rcsb pdb:1YFH|rcsb pdb:8RGG|rcsb pdb:8RGH|rcsb pdb:8RTY|rcsb pdb:8RU2|reactome:R-HSA-5657655|refseq:NP_002403.2|refseq:XP_005252739.1|panther:PTHR46460(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8jqYn7kracNCDGYibTeEcZe2fl81392	rogid:VUvGNp/OF/l9wwMIhPjQG+SBfFM9606	intact-crc:F89F124D89B7AE01|rigid:sKdiU7iSfwTdN5LSfS+f4oHIgN8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P55083	uniprotkb:Q81K85	intact:EBI-2829794|uniprotkb:Q6P680|uniprotkb:A8KAJ1|uniprotkb:A8MVM2|uniprotkb:B4E317|ensembl:ENSP00000299610.5	intact:EBI-2812720|uniprotkb:Q6KL02|uniprotkb:Q6HRN6	psi-mi:mfap4_human(display_long)|uniprotkb:MFAP4(gene name)|psi-mi:MFAP4(display_short)	psi-mi:glga_bacan(display_long)|uniprotkb:glgA(gene name)|psi-mi:glgA(display_short)|uniprotkb:Starch [bacterial glycogen] synthase(gene name synonym)|uniprotkb:BA_5120(locus name)|uniprotkb:GBAA_5120(locus name)|uniprotkb:BAS4758(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829800|imex:IM-13779-3346	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001185624.1|refseq:NP_002395.1|ensembl:ENSG00000166482.12(gene)|ensembl:ENST00000299610.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0007155""(cell adhesion)|go:""GO:0009650""(UV protection)|go:""GO:0010712""(regulation of collagen metabolic process)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071493""(cellular response to UV-B)|go:""GO:0071953""(elastic fiber)|go:""GO:0097435""(supramolecular fiber organization)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR036056|interpro:IPR050373|mint:P55083|rcsb pdb:7ZMK|rcsb pdb:8UN7|reactome:R-HSA-2129379|panther:PTHR19143(orthology-group)"	"interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR011835(Glycogen/starch synthases, ADP-glucose type)|interpro:IPR013534(Starch synthase catalytic region)|go:""GO:0004373""(""alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"")|go:""GO:0005978""(glycogen biosynthetic process)|go:""GO:0009011""(""alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity"")|refseq:WP_011053260.1|refseq:NP_847306.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pudRJmT0Rb32WgBHT7g7KZsSsME9606	rogid:uWEjM8noLfVuOuXNS3DfnaCdS3I1392	intact-crc:0A75FC2A8880F3C2|rigid:JYlC1dEloO45vw/c9NR5hStDKys	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NPJ6	uniprotkb:Q81LQ9	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648.2	intact:EBI-2817908|uniprotkb:Q6KMF4|uniprotkb:E9RE75	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:q81lq9_bacan(display_long)|uniprotkb:comEA(gene name)|psi-mi:comEA(display_short)|uniprotkb:GBAA_4553(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829842|imex:IM-13779-3351	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146.15(gene)|ensembl:ENST00000258648.7(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016592""(mediator complex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070847""(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|panther:PTHR13208(orthology-group)"	"interpro:IPR004509(Competence protein ComEA, helix-hairpin-helix region)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR019554|go:""GO:0003677""(DNA binding)|go:""GO:0006281""(DNA repair)|go:""GO:0015627""(type II protein secretion system complex)|go:""GO:0015628""(protein secretion by the type II secretion system)|go:""GO:0016020""(membrane)|interpro:IPR051675"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	rogid:iEvG41gaFu5NjfUyZipFRqUjSKs1392	intact-crc:1C53A2F2443B09C7|rigid:MXVEf1vT/uQ/pP/5pUlAIG5/0fc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H7Q9	uniprotkb:Q9H1A3	intact:EBI-2823444|uniprotkb:Q6KJD7|uniprotkb:Q6I2U5|uniprotkb:E9R5Y4|uniprotkb:E9R5Y5|uniprotkb:Q81UL4|uniprotkb:A0A0F7RMR7	intact:EBI-2804879|uniprotkb:Q9H1A2|uniprotkb:Q8NBT8|uniprotkb:Q9BWJ7|uniprotkb:Q9Y390|ensembl:ENSP00000350874.3	psi-mi:a0a6l7h7q9_bacan(display_long)|uniprotkb:GBAA_0852(locus name)	psi-mi:metl9_human(display_long)|uniprotkb:DREV(gene name synonym)|uniprotkb:DORA reverse strand protein(gene name synonym)|uniprotkb:METTL9(gene name)|psi-mi:METTL9(display_short)|uniprotkb:Methyltransferase-like protein 9(gene name synonym)|uniprotkb:CGI-81(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829807|imex:IM-13779-3350	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039421|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015421""(ABC-type oligopeptide transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000493196.1|interpro:IPR036640"	"refseq:NP_001070648.1|refseq:NP_057109.3|refseq:NP_001275588.1|refseq:NP_001275589.1|ensembl:ENSG00000197006.15(gene)|ensembl:ENST00000358154.8(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0032259""(methylation)|go:""GO:0106370""(protein-L-histidine N-pros-methyltransferase activity)|interpro:IPR007884(DREV methyltransferase)|interpro:IPR029063|mint:Q9H1A3|rcsb pdb:7Y9C|rcsb pdb:7YF2|rcsb pdb:7YF3|rcsb pdb:7YF4|rcsb pdb:8GZE|rcsb pdb:8GZF|panther:PTHR12890(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:I2iOFxwdUv+WSyGorI6ZN5h40hs1392	rogid:y+kS5qY2f6iIp5xTPC58cOoZfVg9606	intact-crc:0248BC1A5C5DA97B|rigid:+BDwFKEuQO9rv5UCgjean0YmXlY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14814	uniprotkb:Q81N22	intact:EBI-2829828|uniprotkb:Q5T9U5|uniprotkb:Q14815|uniprotkb:Q5T9U6|uniprotkb:D3DVC0|ensembl:ENSP00000271555.5|ensembl:ENSP00000517292.1	intact:EBI-2825434|uniprotkb:Q6KQD4|uniprotkb:E9R2G6	psi-mi:mef2d_human(display_long)|uniprotkb:MEF2D(gene name)|psi-mi:MEF2D(display_short)	psi-mi:q81n22_bacan(display_long)|uniprotkb:GBAA_3395(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829835|imex:IM-13779-3348	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011507871.1|refseq:NP_005911.1|refseq:NP_001258558.1|refseq:XP_005245226.1|refseq:XP_005245227.1|refseq:XP_006711393.1|refseq:XP_006711395.1|refseq:XP_006711396.1|refseq:XP_006711397.1|refseq:XP_016856803.1|refseq:XP_016856804.1|ensembl:ENSG00000116604.19(gene)|ensembl:ENSG00000291761.1(gene)|ensembl:ENST00000348159.9(transcript)|ensembl:ENST00000708596.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001958""(endochondral ossification)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006915""(apoptotic process)|go:""GO:0007399""(nervous system development)|go:""GO:0007512""(adult heart development)|go:""GO:0007517""(muscle organ development)|go:""GO:0030154""(cell differentiation)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|mint:Q14814|rcsb pdb:7X1N|rcsb pdb:8C84|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-525793|reactome:R-HSA-9031628|reactome:R-HSA-9707616|panther:PTHR11945(orthology-group)"	"interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jedvDf/fMyonSO9j1epfMUuj86Y9606	rogid:iewWe12NXZEwAACuzAKCyUPqliY1392	intact-crc:62897DC12F3F10DB|rigid:IPRf0lxFs9rSErqlWipJTOHV5AU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31153	uniprotkb:Q81X77	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|uniprotkb:B4DN45|ensembl:ENSP00000303147.3	intact:EBI-2810439|uniprotkb:Q6HR13|uniprotkb:Q6KKD2	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:gpmi_bacan(display_long)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)|uniprotkb:gpmA(gene name synonym)|uniprotkb:BA_5365(locus name)|uniprotkb:GBAA_5365(locus name)|uniprotkb:BAS4986(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829814|imex:IM-13779-3347	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168906.13(gene)|ensembl:ENST00000306434.8(transcript)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0036094""(small molecule binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048269""(methionine adenosyltransferase complex)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|rcsb pdb:7BHR|rcsb pdb:7BHS|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCF|rcsb pdb:7KCE|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|rcsb pdb:7LNH|rcsb pdb:7RW5|rcsb pdb:7RW7|rcsb pdb:7RWG|rcsb pdb:7RWH|rcsb pdb:7RXV|rcsb pdb:7RXW|rcsb pdb:7RXX|rcsb pdb:8AXZ|rcsb pdb:8OOG|rcsb pdb:8P1T|rcsb pdb:8P1V|rcsb pdb:8P1W|rcsb pdb:8P4H|rcsb pdb:8QDY|rcsb pdb:8QDZ|rcsb pdb:8QE0|rcsb pdb:8QE1|rcsb pdb:8QE2|rcsb pdb:8QE3|rcsb pdb:8XAM|rcsb pdb:8XAR|rcsb pdb:8XB0|reactome:R-HSA-156581|refseq:NP_005902.1|efo:""Orphanet:91387""|panther:PTHR11964(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|rcsb pdb:2IFY|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030435""(sporulation resulting in formation of a cellular spore)|go:""GO:0043937""(regulation of sporulation)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|refseq:WP_001231153.1|interpro:IPR036646|refseq:NP_847539.1|refseq:YP_031225.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	rogid:pxX2Dycc6/EBhmFHPZ5uVcHE6I41392	intact-crc:A4034B033858FA07|rigid:t/FQiGMsybPprhL5LQkcLDk907Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31153	uniprotkb:Q81V26	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|uniprotkb:B4DN45|ensembl:ENSP00000303147.3	intact:EBI-2819073|uniprotkb:Q6KX26|uniprotkb:E9R6E9	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:q81v26_bacan(display_long)|uniprotkb:sph(gene name)|psi-mi:sph(display_short)|uniprotkb:GBAA_0678(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829821|imex:IM-13779-3349	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168906.13(gene)|ensembl:ENST00000306434.8(transcript)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|go:""GO:0034214""(protein hexamerization)|go:""GO:0036094""(small molecule binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048269""(methionine adenosyltransferase complex)|go:""GO:0051291""(protein heterooligomerization)|go:""GO:0061431""(cellular response to methionine)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|rcsb pdb:7BHR|rcsb pdb:7BHS|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCF|rcsb pdb:7KCE|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|rcsb pdb:7LNH|rcsb pdb:7RW5|rcsb pdb:7RW7|rcsb pdb:7RWG|rcsb pdb:7RWH|rcsb pdb:7RXV|rcsb pdb:7RXW|rcsb pdb:7RXX|rcsb pdb:8AXZ|rcsb pdb:8OOG|rcsb pdb:8P1T|rcsb pdb:8P1V|rcsb pdb:8P1W|rcsb pdb:8P4H|rcsb pdb:8QDY|rcsb pdb:8QDZ|rcsb pdb:8QE0|rcsb pdb:8QE1|rcsb pdb:8QE2|rcsb pdb:8QE3|rcsb pdb:8XAM|rcsb pdb:8XAR|rcsb pdb:8XB0|reactome:R-HSA-156581|refseq:NP_005902.1|efo:""Orphanet:91387""|panther:PTHR11964(orthology-group)"	"interpro:IPR017766(Sphingomyelinase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|go:""GO:0004767""(sphingomyelin phosphodiesterase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0031640""(killing of cells of another organism)|interpro:IPR036691|refseq:WP_003287028.1|interpro:IPR038772"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	rogid:tGAKGt3GqJ5maQSOP22dks5UgjQ1392	intact-crc:B992E50338052951|rigid:TMib6BCodSfex9l6JLncQc7XkOg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13503	uniprotkb:A0A6L7HI94	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892.3	intact:EBI-2809670|uniprotkb:Q6KUB6|uniprotkb:Q6I0E9|uniprotkb:E9QZ71|uniprotkb:E9QZ72|uniprotkb:Q81S67|uniprotkb:A0A0F7RKN4	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:a0a6l7hi94_bacan(display_long)|uniprotkb:GBAA_1804(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829890|imex:IM-13779-3354	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR13381(orthology-group)|refseq:NP_004255.2|ensembl:ENSG00000152944.9(gene)|ensembl:ENST00000282892.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070847""(core mediator complex)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110|dip:DIP-31471N"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR013663(Helicase, SWF/SNF/SWI type, bacterial)|interpro:IPR000330(SNF2-related)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR038718|interpro:IPR027417|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016787""(hydrolase activity)|refseq:WP_000507070.1|interpro:IPR049730"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	rogid:UALwsYQ6P5Vi+Y6Ffzu+ItCyX2Y1392	intact-crc:DD001FDD14660534|rigid:wTLpR0b4h+zjOUl/aQ/PrptklOo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P409	uniprotkb:Q13503	intact:EBI-2813887|uniprotkb:Q6KWI9|uniprotkb:E9R481|uniprotkb:A0A2P0HAJ1|uniprotkb:Q81UI1	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892.3	psi-mi:a0a6l8p409_bacan(display_long)|uniprotkb:GBAA_0891(locus name)	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829883|imex:IM-13779-3357	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR036514|go:""GO:0016020""(membrane)|refseq:WP_000792073.1"	"panther:PTHR13381(orthology-group)|refseq:NP_004255.2|ensembl:ENSG00000152944.9(gene)|ensembl:ENST00000282892.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070847""(core mediator complex)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110|dip:DIP-31471N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:I5swgNLd8W/yDwH5AflheV23tYA1392	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	intact-crc:1D5FD11B5B30F003|rigid:Z1pt6nnYKnSjLRUpRqmaixZaskM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13503	uniprotkb:A0A6L8P863	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892.3	intact:EBI-2829870|uniprotkb:Q6KY16|uniprotkb:Q6I4B4|uniprotkb:E9R8Z7|uniprotkb:E9R8Z8|uniprotkb:Q81ZG7|uniprotkb:A0A0F7RI71	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:a0a6l8p863_bacan(display_long)|uniprotkb:purD(gene name)|psi-mi:purD(display_short)|uniprotkb:GARS(gene name synonym)|uniprotkb:Glycinamide ribonucleotide synthetase(gene name synonym)|uniprotkb:Phosphoribosylglycinamide synthetase(gene name synonym)|uniprotkb:GBAA_0299(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829876|imex:IM-13779-3356	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR13381(orthology-group)|refseq:NP_004255.2|ensembl:ENSG00000152944.9(gene)|ensembl:ENST00000282892.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070847""(core mediator complex)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110|dip:DIP-31471N"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR020560|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|refseq:WP_001101947.1|go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR037123"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	rogid:q/uQhQ+IzjJYS3aw8m5MgWnBZ7o1392	intact-crc:DE0CD165F6A3CC41|rigid:doxLMWuXm3m4NQb+lBFAPZVVAmE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13503	uniprotkb:Q81KT8	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892.3	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829856|imex:IM-13779-3355	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR13381(orthology-group)|refseq:NP_004255.2|ensembl:ENSG00000152944.9(gene)|ensembl:ENST00000282892.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070847""(core mediator complex)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110|dip:DIP-31471N"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	intact-crc:259318854FC9B24E|rigid:k79QaFfo90f6srdZ7VRdALkTNjk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULK4	uniprotkb:Q81JW1	intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047.3|uniprotkb:B9TX55	intact:EBI-2816384|uniprotkb:Q6KJT7|uniprotkb:Q6HQG2	psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym)	psi-mi:pyrg_bacan(display_long)|uniprotkb:pyrG(gene name)|psi-mi:pyrG(display_short)|uniprotkb:ctrA(gene name synonym)|uniprotkb:UTP--ammonia ligase(gene name synonym)|uniprotkb:BA_5583(locus name)|uniprotkb:GBAA_5583(locus name)|uniprotkb:BAS5187(locus name)|uniprotkb:Cytidine 5'-triphosphate synthase(gene name synonym)|uniprotkb:Cytidine triphosphate synthetase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829849|imex:IM-13779-3352	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000112282.18(gene)|ensembl:ENST00000368068.8(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006367""(transcription initiation at RNA polymerase II promoter)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0070847""(core mediator complex)|go:""GO:2000409""(positive regulation of T cell extravasation)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|refseq:NP_001257450.1|refseq:NP_001257451.1|refseq:NP_004821.2|refseq:NP_057063.2|efo:""Orphanet:88616""|dip:DIP-31461N|ensembl:ENST00000354577.8|ensembl:ENSP00000346588.4|ensembl:ENST00000368053.8|ensembl:ENSP00000357032.4|ensembl:ENST00000368060.7|ensembl:ENSP00000357039.3|ensembl:ENSP00000357047.3|ensembl:ENST00000539158.1|ensembl:ENSP00000445072.1|panther:PTHR12691(orthology-group)"	"interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR029062|interpro:IPR027417|go:""GO:0003883""(CTP synthase activity)|go:""GO:0004359""(glutaminase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019856""(pyrimidine nucleobase biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0044210""('de novo' CTP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000170456.1|interpro:IPR033828|refseq:NP_847739.1|refseq:YP_031426.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606	rogid:SrGr2YO98Kx1ur7cTIL31MeRXwk1392	intact-crc:25B64EAD26527894|rigid:ix1qifEXPRhKRZU4AN4ylR87HLA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13503	uniprotkb:A0A2C3GDM9	intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892.3	intact:EBI-2821725|uniprotkb:Q6KK75|uniprotkb:E9R3D6|uniprotkb:Q81X21|uniprotkb:A0A1Q4LYL9|uniprotkb:A0A2A8LCK3	psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym)	psi-mi:a0a2c3gdm9_bacan(display_long)|uniprotkb:GBAA_5428(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829863|imex:IM-13779-3353	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR13381(orthology-group)|refseq:NP_004255.2|ensembl:ENSG00000152944.9(gene)|ensembl:ENST00000282892.4(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001824""(blastocyst development)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003899""(DNA-directed RNA polymerase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051123""(RNA polymerase II preinitiation complex assembly)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070847""(core mediator complex)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:8GXQ|rcsb pdb:8GXS|rcsb pdb:8T9D|rcsb pdb:8TQW|rcsb pdb:8TRH|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-9833110|dip:DIP-31471N"	"interpro:IPR002577(Helix-turn-helix, HxlR type)|interpro:IPR011991(Winged helix repressor DNA-binding)|go:""GO:0003677""(DNA binding)|interpro:IPR036388|interpro:IPR036390|refseq:WP_000400857.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/09	rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606	rogid:MYI4P8399Knbn0ivrLmmBdDsvwc1392	intact-crc:38A3FC29D1442929|rigid:LLxQPDu+aeTtk4uA4V6maCM7zRQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HDR8	uniprotkb:Q96EZ8	intact:EBI-2813601|uniprotkb:Q6KMC4|uniprotkb:Q6HT37|uniprotkb:E9QVK2|uniprotkb:E9QVK3|uniprotkb:Q81LM9|uniprotkb:A0A0F7R6G5	intact:EBI-348259|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|ensembl:ENSP00000345358.4|ensembl:ENSP00000448056.1|uniprotkb:Q7Z372	psi-mi:a0a6l7hdr8_bacan(display_long)|uniprotkb:GBAA_4586(locus name)	psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829925|imex:IM-13779-3362	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR019774|go:""GO:0005506""(iron ion binding)|go:""GO:0009072""(aromatic amino acid metabolic process)|go:""GO:0016714""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen)|refseq:WP_000163221.1|interpro:IPR036329|interpro:IPR036951"	"refseq:NP_001012300.1|refseq:NP_006328.2|ensembl:ENSG00000187778.14(gene)|ensembl:ENST00000343810.9(transcript)|ensembl:ENST00000550165.5(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0000723""(telomere maintenance)|go:""GO:0002151""(G-quadruplex RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006282""(regulation of DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0010521""(telomerase inhibitor activity)|go:""GO:0030425""(dendrite)|go:""GO:0031011""(Ino80 complex)|go:""GO:0033044""(regulation of chromosome organization)|go:""GO:0034046""(""poly(G) binding"")|go:""GO:0036211""(protein modification process)|go:""GO:0043204""(perikaryon)|go:""GO:0044545""(NSL complex)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060382""(regulation of DNA strand elongation)|go:""GO:0071339""(MLL1 complex)|go:""GO:1904357""(negative regulation of telomere maintenance via telomere lengthening)|go:""GO:1904507""(positive regulation of telomere maintenance in response to DNA damage)|go:""GO:1904751""(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-9772755|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1|panther:PTHR13233(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UgqbKGjZURf/eUAUwQIMUjWsS6Q1392	rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606	intact-crc:68B25418122A1C6A|rigid:WfVNbmyG76/8cSPF8PFohHgSZXE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HGH8	uniprotkb:Q9P1T7	intact:EBI-2812854|uniprotkb:Q6KMM3|uniprotkb:Q6HTD1|uniprotkb:E9QZR3|uniprotkb:E9QZR4|uniprotkb:A0A2P0HJA3|uniprotkb:Q81LX9	intact:EBI-2812899|uniprotkb:Q9P1T6|ensembl:ENSP00000377126.1	psi-mi:a0a6l7hgh8_bacan(display_long)|uniprotkb:metI(gene name)|psi-mi:metI(display_short)|uniprotkb:GBAA_4480(locus name)	psi-mi:mdfic_human(display_long)|uniprotkb:MDFIC(gene name)|psi-mi:MDFIC(display_short)|uniprotkb:I-mfa domain-containing protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829911|imex:IM-13779-3359	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000277(Cys/Met metabolism, pyridoxal phosphate-dependent enzyme)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0005737""(cytoplasm)|go:""GO:0016846""(carbon-sulfur lyase activity)|go:""GO:0019346""(transsulfuration)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR054542|refseq:WP_000103893.1"	"refseq:NP_001159817.1|refseq:NP_951038.1|ensembl:ENSG00000135272.13(gene)|ensembl:ENST00000393486.6(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030111""(regulation of Wnt signaling pathway)|go:""GO:0030332""(cyclin binding)|go:""GO:0030957""(Tat protein binding)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046328""(regulation of JNK cascade)|go:""GO:0050434""(positive regulation of viral transcription)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR026134|panther:PTHR15304(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7joPHBMLoR4JQC0Sb2jnzu9Omy81392	rogid:Ex7BUM4IA7mjwyl6AA4NOvMF5/A9606	intact-crc:2A0A8B9DDC176BFB|rigid:GYCr4XaD/2Rh3ZbePgjX4s8HIbg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H1C2	uniprotkb:Q93074	intact:EBI-2809848|uniprotkb:Q6KMV0|uniprotkb:Q6HTL0|uniprotkb:E9QWV5|uniprotkb:E9QWV6|uniprotkb:A0A2P0HIT1|uniprotkb:Q81M57	intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193.3	psi-mi:a0a6l7h1c2_bacan(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:GBAA_4397(locus name)|uniprotkb:Recombination protein N(gene name synonym)	psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829897|imex:IM-13779-3358	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0009432""(SOS response)|go:""GO:0043590""(bacterial nucleoid)|refseq:WP_000947756.1"	"ensembl:ENSG00000184634.17(gene)|ensembl:ENST00000374080.8(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001843""(neural tube closure)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0014044""(Schwann cell development)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016592""(mediator complex)|go:""GO:0021510""(spinal cord development)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048702""(embryonic neurocranium morphogenesis)|go:""GO:0060071""(Wnt signaling pathway, planar cell polarity pathway)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0090245""(axis elongation involved in somitogenesis)|go:""GO:1990403""(embryonic brain development)|go:""GO:1990508""(CKM complex)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|interpro:IPR051647|mint:Q93074|rcsb pdb:8TQ2|rcsb pdb:8TQC|rcsb pdb:8TQW|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|reactome:R-HSA-9833110|reactome:R-HSA-9841922|refseq:NP_005111.2|efo:""Orphanet:2728""|efo:""Orphanet:293707""|efo:""Orphanet:776""|efo:""Orphanet:777""|efo:""Orphanet:93932""|efo:""Orphanet:1415""|dip:DIP-31459N|panther:PTHR46007(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:aXVFQ2/u7+QhLnMBoqc0Kc6RtX01392	rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606	intact-crc:C5FA01FCF7BB0FAF|rigid:FAooylVqVLT9CurkxxXS1YKplJo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HEE9	uniprotkb:O15151	intact:EBI-2811961|uniprotkb:Q6HT96|uniprotkb:Q6KMI9|uniprotkb:E9RAC2|uniprotkb:E9RAC3|uniprotkb:Q81LU5|uniprotkb:A0A1J9WIU5	intact:EBI-398437|uniprotkb:Q32SL2|uniprotkb:Q6GS18|uniprotkb:Q8IV83|intact:EBI-3932059|uniprotkb:Q2M2Y2|ensembl:ENSP00000356150.3|intact:EBI-28988565	psi-mi:a0a6l7hee9_bacan(display_long)|uniprotkb:GBAA_4515(locus name)|uniprotkb:sigA(gene name)|psi-mi:sigA(display_short)	psi-mi:mdm4_human(display_long)|uniprotkb:MDM4(gene name)|psi-mi:MDM4(display_short)|uniprotkb:MDMX(gene name synonym)|uniprotkb:p53-binding protein Mdm4(gene name synonym)|uniprotkb:Mdm2-like p53-binding protein(gene name synonym)|uniprotkb:Protein Mdmx(gene name synonym)|uniprotkb:Double minute 4 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829904|imex:IM-13779-3361	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028630|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR050239|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016987""(sigma factor activity)|refseq:WP_000764058.1|interpro:IPR042189|interpro:IPR036388"	"refseq:NP_002384.2|panther:PTHR12183(orthology-group)|refseq:NP_001191101.1|refseq:NP_001191100.1|refseq:NP_001265445.1|refseq:NP_001265446.1|refseq:NP_001265447.1|refseq:NP_001265448.1|ensembl:ENSG00000198625.14(gene)|ensembl:ENST00000367182.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003170""(heart valve development)|go:""GO:0003181""(atrioventricular valve morphogenesis)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003283""(atrial septum development)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019899""(enzyme binding)|go:""GO:0030330""(DNA damage response, signal transduction by p53 class mediator)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0050821""(protein stabilization)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071456""(cellular response to hypoxia)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015458(MDM4/MDMX protein)|interpro:IPR016495(p53 negative regulator Mdm2/Mdm4)|interpro:IPR036443|interpro:IPR036885|interpro:IPR051652|mint:O15151|rcsb pdb:2CR8|rcsb pdb:2MWY|rcsb pdb:2N06|rcsb pdb:2N0U|rcsb pdb:2N0W|rcsb pdb:2N14|rcsb pdb:2VJE|rcsb pdb:2VJF|rcsb pdb:2VYR|rcsb pdb:3DAB|rcsb pdb:3EQY|rcsb pdb:3FDO|rcsb pdb:3FE7|rcsb pdb:3FEA|rcsb pdb:3JZO|rcsb pdb:3JZP|rcsb pdb:3JZQ|rcsb pdb:3LBJ|rcsb pdb:3MQR|rcsb pdb:3U15|rcsb pdb:4RXZ|rcsb pdb:5MNJ|rcsb pdb:5UML|rcsb pdb:5VK1|rcsb pdb:6Q9Q|rcsb pdb:6Q9S|rcsb pdb:6Q9U|rcsb pdb:6Q9W|rcsb pdb:6Q9Y|rcsb pdb:6YR5|rcsb pdb:6YR7|rcsb pdb:7C3Q|rcsb pdb:7C3Y|rcsb pdb:7C44|rcsb pdb:7EL4|rcsb pdb:7KJN|rcsb pdb:7MLA|rcsb pdb:8HDG|rcsb pdb:8IA5|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-5689880|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69541|dip:DIP-24199N|ensembl:ENSP00000356150.3|ensembl:ENST00000367183.7|ensembl:ENSP00000356151.3|ensembl:ENST00000454264.6|ensembl:ENSP00000396840.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/06	rogid:B+oGNayePUrFKBMVM5F7WotZ1Cs1392	rogid:zAL03wG+qlPT5folNjx1ZUJhx/A9606	intact-crc:7AEA51D95AC2E31E|rigid:F7eaXjNN1iUXRjJbQW3mAS4yyFw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P1T7	uniprotkb:A0A6L8Q050	intact:EBI-2812899|uniprotkb:Q9P1T6|ensembl:ENSP00000377126.1	intact:EBI-2812424|uniprotkb:Q6HS63|uniprotkb:Q6F089|uniprotkb:E9RAL4|uniprotkb:E9RAL5|uniprotkb:Q81KQ7|uniprotkb:A0A0F7RCB3	psi-mi:mdfic_human(display_long)|uniprotkb:MDFIC(gene name)|psi-mi:MDFIC(display_short)|uniprotkb:I-mfa domain-containing protein(gene name synonym)	psi-mi:a0a6l8q050_bacan(display_long)|uniprotkb:GBAA_4933(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829918|imex:IM-13779-3360	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001159817.1|refseq:NP_951038.1|ensembl:ENSG00000135272.13(gene)|ensembl:ENST00000393486.6(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0030111""(regulation of Wnt signaling pathway)|go:""GO:0030332""(cyclin binding)|go:""GO:0030957""(Tat protein binding)|go:""GO:0042308""(negative regulation of protein import into nucleus)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046328""(regulation of JNK cascade)|go:""GO:0050434""(positive regulation of viral transcription)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR026134|panther:PTHR15304(orthology-group)"	"interpro:IPR035097|interpro:IPR000787(Peptidase M29, aminopeptidase II)|interpro:IPR052170|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_000654736.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Ex7BUM4IA7mjwyl6AA4NOvMF5/A9606	rogid:Ca6ZxzgWZSbnRiXpfkXmNm3rVl01392	intact-crc:D4DCFDC2D3735D5D|rigid:IAjYsFoHt/2X7I9KONn1/pxj1TE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IX19	uniprotkb:Q81WR4	intact:EBI-2816356|uniprotkb:Q8IX20	intact:EBI-2813120|uniprotkb:Q6KP44|uniprotkb:Q6HUW8	psi-mi:mcem1_human(display_long)|uniprotkb:MCEMP1(gene name)|psi-mi:MCEMP1(display_short)|uniprotkb:C19orf59(gene name synonym)	psi-mi:mutl_bacan(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:BA_3904(locus name)|uniprotkb:GBAA_3904(locus name)|uniprotkb:BAS3617(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829939|imex:IM-13779-3363	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_777578.2|go:""GO:0005886""(plasma membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0070821""(tertiary granule membrane)|interpro:IPR038818|reactome:R-HSA-6798695|panther:PTHR37856(orthology-group)"	"interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020667|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR038973|go:""GO:0005524""(ATP binding)|go:""GO:0006298""(mismatch repair)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030983""(mismatched DNA binding)|go:""GO:0032300""(mismatch repair complex)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|refseq:WP_000516478.1|interpro:IPR036890|interpro:IPR037198|interpro:IPR042120|interpro:IPR042121|refseq:NP_846151.1|refseq:YP_029870.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jkUrd4i0968GzmEaxNrRnNAaRBE9606	rogid:OVMVMr8TlQnT2VuMnSQlFsmQhbU1392	intact-crc:973DE5B6CCEE15B4|rigid:4pgnpzCSP0mfpmwLbMlXtIcQ11w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60318	uniprotkb:Q81KK8	intact:EBI-308480|uniprotkb:Q2M3C1|uniprotkb:Q9UMT4|uniprotkb:C9JL56|uniprotkb:Q6PJP6|uniprotkb:Q9BSY5|ensembl:ENSP00000291688.1|ensembl:ENSP00000380820.1	intact:EBI-2822258|uniprotkb:Q6KLB4|uniprotkb:E9R5P7	psi-mi:ganp_human(display_long)|uniprotkb:MCM3AP(gene name)|psi-mi:MCM3AP(display_short)|uniprotkb:GANP(gene name synonym)|uniprotkb:KIAA0572(gene name synonym)|uniprotkb:MAP80(gene name synonym)|uniprotkb:80 kDa MCM3-associated protein(gene name synonym)|uniprotkb:MCM3 acetylating protein(gene name synonym)|uniprotkb:MCM3 acetyltransferase(gene name synonym)	psi-mi:q81kk8_bacan(display_long)|uniprotkb:GBAA_4989(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829932|imex:IM-13779-3367	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003897.2|refseq:XP_005261262.1|refseq:XP_005261260.1|refseq:XP_005261261.1|dip:DIP-31696N|interpro:IPR031907|interpro:IPR031908|interpro:IPR031910|interpro:IPR034265|ensembl:ENSG00000160294.11(gene)|ensembl:ENST00000291688.6(transcript)|ensembl:ENST00000397708.1(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0010484""(histone H3 acetyltransferase activity)|go:""GO:0015031""(protein transport)|go:""GO:0016446""(somatic hypermutation of immunoglobulin genes)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0031965""(nuclear membrane)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0034728""(nucleosome organization)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042393""(histone binding)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0044615""(nuclear pore nuclear basket)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0070390""(transcription export complex 2)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR035979|interpro:IPR045107|mint:O60318|rcsb pdb:4DHX|panther:PTHR12436(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7WgKNrY4EPZGmfDj7es5SWEfTYM9606	rogid:IiAIRE+C5ddv3SFzgMBN5yxqO8Q1392	intact-crc:364783BB2F109BD2|rigid:JTKtcutS8suy/CD6ta7/Ub+c63E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PY32	uniprotkb:Q9NR56	intact:EBI-2829967|uniprotkb:Q6KLY5|uniprotkb:Q6HSP2|uniprotkb:E9R6R5|uniprotkb:E9R6R6|uniprotkb:Q81L89|uniprotkb:A0A0J1HKE1	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486.6|ensembl:ENSP00000418108.1	psi-mi:a0a6l8py32_bacan(display_long)|uniprotkb:GBAA_4739(locus name)	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829972|imex:IM-13779-3365	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007168(PspC)|refseq:WP_000038792.1|go:""GO:0005886""(plasma membrane)|interpro:IPR052027"	"refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSG00000152601.18(gene)|ensembl:ENST00000282486.10(transcript)|ensembl:ENST00000463374.5(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007399""(nervous system development)|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030326""(embryonic limb morphogenesis)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045445""(myoblast differentiation)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR054429|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|refseq:NP_001300986.1|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1|panther:PTHR12675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HutG4t4jlYwGw5J6iITpFCH4haA1392	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	intact-crc:BE0DE4A331D8829B|rigid:JuiGo5H2X9MQQE6xIrUhAAu95Kg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NYE5	uniprotkb:Q14703	intact:EBI-2817557|uniprotkb:Q6KQE3|uniprotkb:Q6HW92|uniprotkb:E9RCX9|uniprotkb:E9RCY0|uniprotkb:Q81N31|uniprotkb:A0A0F7R9H8	intact:EBI-2829953|uniprotkb:Q24JQ2|uniprotkb:Q9UF67|uniprotkb:A8K6V8|ensembl:ENSP00000344223.3	psi-mi:a0a6l8nye5_bacan(display_long)|uniprotkb:GBAA_3386(locus name)	psi-mi:mbtp1_human(display_long)|uniprotkb:MBTPS1(gene name)|psi-mi:MBTPS1(display_short)|uniprotkb:KIAA0091(gene name synonym)|uniprotkb:S1P(gene name synonym)|uniprotkb:SKI1(gene name synonym)|uniprotkb:Endopeptidase S1P(gene name synonym)|uniprotkb:Subtilisin/kexin-isozyme 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829960|imex:IM-13779-3364	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031599|go:""GO:0016020""(membrane)|refseq:WP_000036876.1"	"refseq:NP_003782.1|ensembl:ENSG00000140943.18(gene)|ensembl:ENST00000343411.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005795""(Golgi stack)|go:""GO:0006508""(proteolysis)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0007040""(lysosome organization)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0016485""(protein processing)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0031293""(membrane protein intracellular domain proteolysis)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036500""(ATF6-mediated unfolded protein response)|go:""GO:0045540""(regulation of cholesterol biosynthetic process)|go:""GO:0051604""(protein maturation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023828|interpro:IPR034185|interpro:IPR036852|interpro:IPR050131|interpro:IPR055143|mint:Q14703|rcsb pdb:8UW8|rcsb pdb:8UWC|reactome:R-HSA-1655829|reactome:R-HSA-381033|reactome:R-HSA-381426|reactome:R-HSA-8874177|reactome:R-HSA-8874211|reactome:R-HSA-8957275|reactome:R-HSA-8963889|panther:PTHR43806(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RiOIObdF308awfb6BFlKYayiEtw1392	rogid:Szqa2FHer6aXjbHXgnXIhawbnNM9606	intact-crc:F27F316970A4B6FA|rigid:ERr+zb1Z84j/2RF3uleQaA98D3g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IX19	uniprotkb:A0A6L8P242	intact:EBI-2816356|uniprotkb:Q8IX20	intact:EBI-2821152|uniprotkb:Q6HUC1|uniprotkb:Q6KNK8|uniprotkb:E9RCL6|uniprotkb:E9RCL7|uniprotkb:Q81W74|uniprotkb:A0A0F7RDJ6	psi-mi:mcem1_human(display_long)|uniprotkb:MCEMP1(gene name)|psi-mi:MCEMP1(display_short)|uniprotkb:C19orf59(gene name synonym)	psi-mi:a0a6l8p242_bacan(display_long)|uniprotkb:GBAA_4108(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829946|imex:IM-13779-3366	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_777578.2|go:""GO:0005886""(plasma membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0070821""(tertiary granule membrane)|interpro:IPR038818|reactome:R-HSA-6798695|panther:PTHR37856(orthology-group)"	interpro:IPR028985|refseq:WP_000065132.1|interpro:IPR041270	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jkUrd4i0968GzmEaxNrRnNAaRBE9606	rogid:F4z1OBx8X2SzPlB7SF8B4YTdXRI1392	intact-crc:9F8C7A184E76FD17|rigid:wx3YtRlXNPtSfC1/uFYyQz4pDPM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P27448	uniprotkb:Q81VT8	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	intact:EBI-2811891|uniprotkb:Q6I4U2	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830007|imex:IM-13779-3372	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	intact-crc:40035E7C2F8B4DB5|rigid:6mgUur4qbrksbUC1KML3m9h690o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PBV3	uniprotkb:Q9P267	intact:EBI-2824051|uniprotkb:Q6HQR8|uniprotkb:Q6KK36|uniprotkb:E9QZE9|uniprotkb:E9QZF0|uniprotkb:Q81WY2|uniprotkb:A0A0F7RAJ9	intact:EBI-311373|uniprotkb:A7E2B1|uniprotkb:A5HMQ4|uniprotkb:Q9NUV6|uniprotkb:Q53SR1|ensembl:ENSP00000386049.1	psi-mi:a0a6l8pbv3_bacan(display_long)|uniprotkb:GBAA_5470(locus name)	psi-mi:mbd5_human(display_long)|uniprotkb:MBD5(gene name)|psi-mi:MBD5(display_short)|uniprotkb:KIAA1461(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829979|imex:IM-13779-3368	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR012160(Membrane sulphatase, HI1246-related)|interpro:IPR000917(Sulphatase)|go:""GO:0005886""(plasma membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_000665364.1|interpro:IPR050448"	"efo:""Orphanet:178469""|efo:""Orphanet:228402""|ensembl:ENSG00000204406.14(gene)|ensembl:ENST00000407073.5(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0007399""(nervous system development)|go:""GO:0010369""(chromocenter)|go:""GO:0030496""(midbody)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0050795""(regulation of behavior)|go:""GO:0060399""(positive regulation of growth hormone receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000313(PWWP)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|reactome:R-HSA-5689603|refseq:NP_060798.2|panther:PTHR16112(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0ODA76hjR1X3Gra4Y11TcVgihH41392	rogid:3h6aGO+XvdJ82StRzy6BtzD6IPI9606	intact-crc:9FE58B01476F8496|rigid:A5O3YyRSMFcde4d+IoIcFn1cvP8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43243	uniprotkb:Q81VT8	intact:EBI-352602|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5|ensembl:ENSP00000378284.3|ensembl:ENSP00000482895.1	intact:EBI-2811891|uniprotkb:Q6I4U2	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829993|imex:IM-13779-3369	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000015479.20(gene)|ensembl:ENST00000394805.8(transcript)|ensembl:ENST00000618441.5(transcript)|go:""GO:0001825""(blastocyst formation)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003170""(heart valve development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005634""(nucleus)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_001181885.1|refseq:NP_001269207.1|refseq:NP_061322.2|refseq:NP_954659.1|efo:""Orphanet:600""|efo:""Orphanet:803""|panther:PTHR15592(orthology-group)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	intact-crc:C59A7B017F53C8E7|rigid:Um6ol/Ke7kzfcpC4Bkk8SMPubIo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43243	uniprotkb:A0A6L8PBE8	intact:EBI-352602|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5|ensembl:ENSP00000378284.3|ensembl:ENSP00000482895.1	intact:EBI-2810254|uniprotkb:Q6KWK3|uniprotkb:Q6I2S2|uniprotkb:E9QWW6|uniprotkb:E9QWW7|uniprotkb:Q81UJ3|uniprotkb:A0A0F7RLP7	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	psi-mi:a0a6l8pbe8_bacan(display_long)|uniprotkb:GBAA_0876(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830000|imex:IM-13779-3370	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000015479.20(gene)|ensembl:ENST00000394805.8(transcript)|ensembl:ENST00000618441.5(transcript)|go:""GO:0001825""(blastocyst formation)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003170""(heart valve development)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003723""(RNA binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005634""(nucleus)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0035198""(miRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_001181885.1|refseq:NP_001269207.1|refseq:NP_061322.2|refseq:NP_954659.1|efo:""Orphanet:600""|efo:""Orphanet:803""|panther:PTHR15592(orthology-group)"	"interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR025110|go:""GO:0003824""(catalytic activity)|interpro:IPR050237|interpro:IPR042099|interpro:IPR045851|refseq:WP_000282022.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	rogid:Z5sCT05VbUe0hkm9GioLEacM3ps1392	intact-crc:6CBDD56CE69A14CD|rigid:0BIYAPHJ3dNTJpRM/mvVnTn6Lpw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H1P2	uniprotkb:Q9P267	intact:EBI-2816827|uniprotkb:Q6KP89|uniprotkb:Q6HV14|uniprotkb:E9QRK7|uniprotkb:E9QRK8|uniprotkb:Q81WW1	intact:EBI-311373|uniprotkb:A7E2B1|uniprotkb:A5HMQ4|uniprotkb:Q9NUV6|uniprotkb:Q53SR1|ensembl:ENSP00000386049.1	psi-mi:a0a6l7h1p2_bacan(display_long)|uniprotkb:chi36(gene name)|psi-mi:chi36(display_short)|uniprotkb:GBAA_3854(locus name)	psi-mi:mbd5_human(display_long)|uniprotkb:MBD5(gene name)|psi-mi:MBD5(display_short)|uniprotkb:KIAA1461(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2829986|imex:IM-13779-3371	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011583(Chitinase II)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR050542|refseq:WP_003159224.1|rcsb pdb:5KZ6"	"efo:""Orphanet:178469""|efo:""Orphanet:228402""|ensembl:ENSG00000204406.14(gene)|ensembl:ENST00000407073.5(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0007399""(nervous system development)|go:""GO:0010369""(chromocenter)|go:""GO:0030496""(midbody)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0050795""(regulation of behavior)|go:""GO:0060399""(positive regulation of growth hormone receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000313(PWWP)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|reactome:R-HSA-5689603|refseq:NP_060798.2|panther:PTHR16112(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GgNoHnl7Gk+gJmu/W5GGsmJB1qw1392	rogid:3h6aGO+XvdJ82StRzy6BtzD6IPI9606	intact-crc:F504E4D54F4C40AE|rigid:5WcN0Mkd3ImsfaWOt1JJJ0be608	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81LB8	uniprotkb:P27448	intact:EBI-2810158|uniprotkb:Q6HSS1|uniprotkb:Q6KM14	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	psi-mi:tig_bacan(display_long)|uniprotkb:tig(gene name)|psi-mi:tig(display_short)|uniprotkb:PPIase(gene name synonym)|uniprotkb:BAS4370(locus name)|uniprotkb:BA_4705(locus name)|uniprotkb:GBAA_4705(locus name)	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830021|imex:IM-13779-3373	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR027304|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR005215(Trigger factor)|interpro:IPR008880(Trigger factor, C-terminal, bacterial)|interpro:IPR008881(Trigger factor, ribosome-binding, bacterial)|go:""GO:0005737""(cytoplasm)|go:""GO:0015031""(protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043335""(protein unfolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051083""('de novo' cotranslational protein folding)|go:""GO:0051301""(cell division)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|refseq:WP_000729253.1|interpro:IPR036611|interpro:IPR037041|refseq:NP_846918.1|refseq:YP_030617.1|interpro:IPR046357"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:AXRPk6I10MtZssV4TGaiiOnZ0/o1392	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	intact-crc:02B3247C2F8F4FD0|rigid:l5GG3/11aroVry9Akbpy41ZsoTo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PCK7	uniprotkb:Q15555	intact:EBI-2810879|uniprotkb:Q6KQA6|uniprotkb:Q6HW50|uniprotkb:E9QU09|uniprotkb:E9QU10|uniprotkb:A0A2P0HGJ3|uniprotkb:Q81MY7	intact:EBI-739717|uniprotkb:Q9UQ33|uniprotkb:B2RE21|uniprotkb:B3KR39|uniprotkb:B7Z2L3|uniprotkb:E9PHR3|uniprotkb:F5H1V8|ensembl:ENSP00000300249.4|uniprotkb:B4DJV4|uniprotkb:G5E9I6	psi-mi:a0a6l8pck7_bacan(display_long)|uniprotkb:GBAA_3432(locus name)|uniprotkb:tkt1(gene name)|psi-mi:tkt1(display_short)	psi-mi:mare2_human(display_long)|uniprotkb:MAPRE2(gene name)|psi-mi:MAPRE2(display_short)|uniprotkb:RP1(gene name synonym)|uniprotkb:APC-binding protein EB2(gene name synonym)|uniprotkb:End-binding protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830035|imex:IM-13779-3374	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033247|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR029061|go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|refseq:WP_000193036.1|interpro:IPR049557"	"efo:""Orphanet:2505""|ensembl:ENSG00000166974.13(gene)|ensembl:ENST00000300249.10(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0005925""(focal adhesion)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031110""(regulation of microtubule polymerization or depolymerization)|go:""GO:0032014""(positive regulation of ARF protein signal transduction)|go:""GO:0035371""(microtubule plus-end)|go:""GO:0035372""(protein localization to microtubule)|go:""GO:0042802""(identical protein binding)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0051010""(microtubule plus-end binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051233""(spindle midzone)|go:""GO:0051301""(cell division)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0120183""(positive regulation of focal adhesion disassembly)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|mint:Q15555|refseq:NP_001137298.1|refseq:NP_001137299.1|refseq:NP_001243349.1|refseq:NP_055083.1|panther:PTHR10623(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CAmYX1bWNU1J1p+yojcrnbiE0Ww1392	rogid:rQ5GWouV1PQve0kbnqZy9x9bTMA9606	intact-crc:B6DE245B26DC83E6|rigid:oX7Kp30TyemzAQ4fdc8oqmAYHF4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H8J5	uniprotkb:A0A6L7HDS8	intact:EBI-2830042|uniprotkb:Q8NEC1|uniprotkb:Q9NW60|ensembl:ENSP00000438205.1|ensembl:ENSP00000487587.1	intact:EBI-2830047|uniprotkb:Q6HT46|uniprotkb:Q6KMD4|uniprotkb:E9RDY7|uniprotkb:E9RDY8|uniprotkb:Q81LN9|uniprotkb:A0A0F7R6H3	psi-mi:mans1_human(display_long)|uniprotkb:MANSC1(gene name)|psi-mi:MANSC1(display_short)|uniprotkb:LOH12CR3(gene name synonym)|uniprotkb:Loss of heterozygosity 12 chromosomal region 3 protein(gene name synonym)|uniprotkb:UNQ316/PRO361(orf name)	psi-mi:a0a6l7hds8_bacan(display_long)|uniprotkb:GBAA_4574(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830052|imex:IM-13779-3375	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060520.2|refseq:XP_016875020.1|ensembl:ENSG00000111261.14(gene)|ensembl:ENSG00000281818.3(gene)|ensembl:ENST00000535902.6(transcript)|ensembl:ENST00000629245.3(transcript)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0016020""(membrane)|interpro:IPR011106(Seven cysteines, N-terminal)|interpro:IPR013980(Seven cysteines)|panther:PTHR16021(orthology-group)"	"interpro:IPR001952(Alkaline phosphatase)|interpro:IPR018299|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|refseq:WP_000714932.1|go:""GO:0004035""(alkaline phosphatase activity)|go:""GO:0046872""(metal ion binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3+UHfcOfmH/4oOuy2IVPYeZfHgc9606	rogid:qcK2lbKAnLNBCyTh7mfbbXakJZA1392	intact-crc:3A228FB6BE9BC340|rigid:wS/MCmnN9/1v7pcnk7F56w7GpuI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HRA4	uniprotkb:P27448	intact:EBI-2813473|uniprotkb:Q6HQQ3|uniprotkb:Q6KK24|uniprotkb:E9R8B1|uniprotkb:E9R8B2|uniprotkb:Q81K50|uniprotkb:A0A0F7R5G0	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	psi-mi:a0a6l7hra4_bacan(display_long)|uniprotkb:GBAA_5487(locus name)	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830014|imex:IM-13779-3377	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022138|interpro:IPR000330(SNF2-related)|interpro:IPR038718|interpro:IPR027417|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)|refseq:WP_000610083.1|interpro:IPR049730"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Cs/6ntowxGUivXGkMJr5JhYRMVk1392	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	intact-crc:13BF88646BD641A7|rigid:C1Van1GuQI81Qwpu9xW3yH5XXS0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HIP1	uniprotkb:P27448	intact:EBI-2818994|uniprotkb:Q6KTX7|uniprotkb:Q6HZZ8|uniprotkb:E9QQR7|uniprotkb:E9QQR8|uniprotkb:Q81RS1|uniprotkb:A0A0F7RD99	intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397.2	psi-mi:a0a6l7hip1_bacan(display_long)|uniprotkb:thrC(gene name)|psi-mi:thrC(display_short)|uniprotkb:GBAA_1969(locus name)	psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830028|imex:IM-13779-3376	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR000634(Serine/threonine dehydratase, pyridoxal-phosphate-binding site)|interpro:IPR004450(Threonine synthase)|interpro:IPR026260|go:""GO:0003941""(L-serine ammonia-lyase activity)|go:""GO:0004794""(threonine deaminase activity)|go:""GO:0004795""(threonine synthase activity)|go:""GO:0006565""(L-serine catabolic process)|go:""GO:0006567""(threonine catabolic process)|go:""GO:0009088""(threonine biosynthetic process)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:WP_000276457.1|interpro:IPR050147|interpro:IPR036052"	"refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413.19(gene)|ensembl:ENST00000429436.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030425""(dendrite)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0036289""(peptidyl-serine autophosphorylation)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050321""(tau-protein kinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR049508|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7P1L|rcsb pdb:8UOH|rcsb pdb:8UOI|rcsb pdb:8UOK|rcsb pdb:8UOL|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|panther:PTHR24346(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:aSA5B1YgN8K7wrZg3/+6gJiFsJY1392	rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606	intact-crc:075B776AD0331E6F|rigid:wi/rXx3+SpCEO5vwNxoHuyRwQTw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9RMZ3	uniprotkb:Q9Y2U8	intact:EBI-2820320|uniprotkb:A0A6L7HBM1	intact:EBI-2561428|uniprotkb:Q9NT47|uniprotkb:Q9NYA5|ensembl:ENSP00000308369.2|intact:EBI-40264392	psi-mi:q9rmz3_bacan(display_long)|uniprotkb:capR(gene name)|psi-mi:capR(display_short)|uniprotkb:GBAA_pXO2_0040(locus name)	psi-mi:man1_human(display_long)|uniprotkb:MAN1(gene name synonym)|uniprotkb:LEM domain-containing protein 3(gene name synonym)|uniprotkb:LEMD3(gene name)|psi-mi:LEMD3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830066|imex:IM-13779-3381	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000400406.1|refseq:NP_053194.1|interpro:IPR025669|interpro:IPR027417|interpro:IPR050678	"ensembl:ENSG00000174106.3(gene)|ensembl:ENST00000308330.3(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0016020""(membrane)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032926""(negative regulation of activin receptor signaling pathway)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018996|interpro:IPR034394|interpro:IPR035979|interpro:IPR041885|interpro:IPR052277|mint:Q9Y2U8|rcsb pdb:2CH0|rcsb pdb:5ZOJ|rcsb pdb:5ZOK|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001161086.1|refseq:NP_055134.2|efo:""Orphanet:166119""|efo:""Orphanet:1879""|efo:""Orphanet:94063""|panther:PTHR48036(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aAYoIttBfJ51/60pEmBMu1KAreU1392	rogid:8AILzxAZLbxCAzlJ7oPg9WybOmY9606	intact-crc:58787F05BC4CCF56|rigid:8VcSlS4YiHmH3K3n9RECRRJl+64	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2805038	uniprotkb:A0A6L7HC63	-	intact:EBI-2811370|uniprotkb:Q6KTZ3|uniprotkb:Q6I014|uniprotkb:E9QYA2|uniprotkb:E9QYA3|uniprotkb:Q81RT7|uniprotkb:A0A0F7RJ72	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	psi-mi:a0a6l7hc63_bacan(display_long)|uniprotkb:GBAA_1950(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830085|imex:IM-13779-3380	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR018044|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0071555""(cell wall organization)|refseq:WP_000825873.1"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	rogid:C+GkPog4qlTLKuFTOFPtKPvk7yQ1392	intact-crc:0F5445467FEA95DE|rigid:LqVZVfKtAB5gmY9S2gwH2Ev3h+o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PSY1	intact:EBI-2805038	intact:EBI-2830076|uniprotkb:Q6KVJ8|uniprotkb:Q6I1Q6|uniprotkb:E9R7H1|uniprotkb:E9R7H2|uniprotkb:Q81TH3|uniprotkb:A0A0F7RHL4	-	psi-mi:a0a6l8psy1_bacan(display_long)|uniprotkb:GBAA_1302(locus name)	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830073|imex:IM-13779-3379	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004869(MMPL)|interpro:IPR000731(Sterol-sensing 5TM box)|refseq:WP_000856456.1|go:""GO:0005886""(plasma membrane)|interpro:IPR050545"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1rHBowuUxaMkL/9otK2QWWc9U+U1392	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	intact-crc:BC07DD27A047203D|rigid:YeoIFpE/IPeXwpeqKdU64sTzOJw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2U8	uniprotkb:Q81LK0	intact:EBI-2561428|uniprotkb:Q9NT47|uniprotkb:Q9NYA5|ensembl:ENSP00000308369.2|intact:EBI-40264392	intact:EBI-2824375|uniprotkb:Q6HT06|uniprotkb:Q6KM96	psi-mi:man1_human(display_long)|uniprotkb:MAN1(gene name synonym)|uniprotkb:LEM domain-containing protein 3(gene name synonym)|uniprotkb:LEMD3(gene name)|psi-mi:LEMD3(display_short)	psi-mi:sya_bacan(display_long)|uniprotkb:alaS(gene name)|psi-mi:alaS(display_short)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:BAS4284(locus name)|uniprotkb:BA_4616(locus name)|uniprotkb:GBAA_4616(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830059|imex:IM-13779-3378	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000174106.3(gene)|ensembl:ENST00000308330.3(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0016020""(membrane)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032926""(negative regulation of activin receptor signaling pathway)|go:""GO:1990446""(U1 snRNP binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018996|interpro:IPR034394|interpro:IPR035979|interpro:IPR041885|interpro:IPR052277|mint:Q9Y2U8|rcsb pdb:2CH0|rcsb pdb:5ZOJ|rcsb pdb:5ZOK|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001161086.1|refseq:NP_055134.2|efo:""Orphanet:166119""|efo:""Orphanet:1879""|efo:""Orphanet:94063""|panther:PTHR48036(orthology-group)"	"interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR018162|interpro:IPR018165|interpro:IPR018164|interpro:IPR023033|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|go:""GO:0000049""(tRNA binding)|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004813""(alanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006419""(alanyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016740""(transferase activity)|refseq:WP_000811843.1|interpro:IPR050058|refseq:NP_846835.1|refseq:YP_030532.1|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8AILzxAZLbxCAzlJ7oPg9WybOmY9606	rogid:N4txLKm2QF5Jq9izywmCim5mA5c1392	intact-crc:20FEE50BCDAC5D9E|rigid:ktrmMsV5MixY4rJ3nQneM9K791U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P242	intact:EBI-2805038	intact:EBI-2821152|uniprotkb:Q6HUC1|uniprotkb:Q6KNK8|uniprotkb:E9RCL6|uniprotkb:E9RCL7|uniprotkb:Q81W74|uniprotkb:A0A0F7RDJ6	-	psi-mi:a0a6l8p242_bacan(display_long)|uniprotkb:GBAA_4108(locus name)	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830092|imex:IM-13779-3382	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR028985|refseq:WP_000065132.1|interpro:IPR041270	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:F4z1OBx8X2SzPlB7SF8B4YTdXRI1392	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	intact-crc:47FBEC27A0B6C1F2|rigid:8E2DNCO1EGPOrcKPb0/I7uncQe4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
intact:EBI-2805038	uniprotkb:A0A6L8PW84	-	intact:EBI-2810036|uniprotkb:Q6I0D7|uniprotkb:Q6KUA7|uniprotkb:E9QSG5|uniprotkb:E9QSG6|uniprotkb:Q81S56|uniprotkb:A0A0F7RJG7	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	psi-mi:a0a6l8pw84_bacan(display_long)|uniprotkb:GBAA_1818(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830111|imex:IM-13779-3383	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"interpro:IPR002901(Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase)|interpro:IPR001119(S-layer homology region)|refseq:WP_000756001.1|interpro:IPR051465|go:""GO:0004040""(amidase activity)|go:""GO:0030115""(S-layer)"	"psi-mi:""MI:0469""(intact)"	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	rogid:rvtlwru3355qXbTQawe6Hx/9UN01392	intact-crc:EB431927A17F40F3|rigid:e6ayIoXmhNb+fgKmCZ82izeHeIw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H2Q9	uniprotkb:Q8N5G2	intact:EBI-2810400|uniprotkb:Q6KTQ9|uniprotkb:Q6HZS4|uniprotkb:E9RAZ3|uniprotkb:E9RAZ4|uniprotkb:Q81RJ7|uniprotkb:A0A0F7RD30	intact:EBI-2683507|uniprotkb:Q2TLX5|uniprotkb:Q2TLX6|uniprotkb:B1AK00|uniprotkb:Q9NVG6|ensembl:ENSP00000363463.4	psi-mi:a0a6l7h2q9_bacan(display_long)|uniprotkb:GBAA_2047(locus name)	psi-mi:macoi_human(display_long)|uniprotkb:Transmembrane protein 57(gene name synonym)|uniprotkb:MACO1(gene name)|psi-mi:MACO1(display_short)|uniprotkb:TMEM57(gene name synonym)|uniprotkb:Macoilin-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830118|imex:IM-13779-3386	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:WP_000216920.1	"refseq:NP_001269493.1|refseq:NP_060672.2|ensembl:ENSG00000204178.11(gene)|ensembl:ENST00000374343.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0006935""(chemotaxis)|go:""GO:0007420""(brain development)|go:""GO:0008017""(microtubule binding)|go:""GO:0023041""(neuronal signal transduction)|go:""GO:0030424""(axon)|go:""GO:0030867""(rough endoplasmic reticulum membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0045202""(synapse)|interpro:IPR019130|mint:Q8N5G2|reactome:R-HSA-8980692|reactome:R-HSA-9013106|panther:PTHR13289(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H+yb15aOHMi9sIfuMqerdtx927Y1392	rogid:k8wUq+ZSQRPwhRdj2c8pgzgQEgU9606	intact-crc:AE1E92BE77662E3B|rigid:RjYUfd4Tpr3Hw4uyPfu8u5YIh/c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7REA8	intact:EBI-2805038	intact:EBI-2830099|uniprotkb:Q6KNH6|uniprotkb:Q6HU92|uniprotkb:E9QWE2|uniprotkb:E9QWE3|uniprotkb:Q81W39	-	psi-mi:a0a0f7rea8_bacan(display_long)|uniprotkb:GBAA_4144(locus name)	psi-mi:a0a1l1m261_human(display_short)|psi-mi:EBI-2805038(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830104|imex:IM-13779-3387	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR029033|go:""GO:0004331""(fructose-2,6-bisphosphate 2-phosphatase activity)|go:""GO:0005829""(cytosol)|go:""GO:0043456""(regulation of pentose-phosphate shunt)|go:""GO:0045820""(negative regulation of glycolytic process)|interpro:IPR051695"	uniprotkb:A0A1L1M261(uniprot-removed-ac)	"psi-mi:""MI:0469""(intact)"	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2dUNwO26Nw7A3XTV9xY6twTNqGo1392	rogid:OcVLvfuPXntxGaVrJzUWBAMZ2yk9606	intact-crc:3DB5FB11CE5E2E86|rigid:pgY5hwTWqH3j3N32h0rNeVjofD8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HPH6	uniprotkb:Q8N5G2	intact:EBI-2830140|uniprotkb:Q6KKN0|uniprotkb:Q6HRB3|uniprotkb:E9R3Z7|uniprotkb:E9R3Z8|uniprotkb:Q81XI0|uniprotkb:A0A0J1HL76	intact:EBI-2683507|uniprotkb:Q2TLX5|uniprotkb:Q2TLX6|uniprotkb:B1AK00|uniprotkb:Q9NVG6|ensembl:ENSP00000363463.4	psi-mi:a0a6l7hph6_bacan(display_long)|uniprotkb:GBAA_5257(locus name)	psi-mi:macoi_human(display_long)|uniprotkb:Transmembrane protein 57(gene name synonym)|uniprotkb:MACO1(gene name)|psi-mi:MACO1(display_short)|uniprotkb:TMEM57(gene name synonym)|uniprotkb:Macoilin-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830137|imex:IM-13779-3385	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR021586|interpro:IPR002831(Transcriptional regulator TrmB)|refseq:WP_000939488.1|interpro:IPR036388|interpro:IPR036390|interpro:IPR051797	"refseq:NP_001269493.1|refseq:NP_060672.2|ensembl:ENSG00000204178.11(gene)|ensembl:ENST00000374343.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0006935""(chemotaxis)|go:""GO:0007420""(brain development)|go:""GO:0008017""(microtubule binding)|go:""GO:0023041""(neuronal signal transduction)|go:""GO:0030424""(axon)|go:""GO:0030867""(rough endoplasmic reticulum membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0044306""(neuron projection terminus)|go:""GO:0045202""(synapse)|interpro:IPR019130|mint:Q8N5G2|reactome:R-HSA-8980692|reactome:R-HSA-9013106|panther:PTHR13289(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M9WqLISUjTSw2MNoDGcq/BoXAEM1392	rogid:k8wUq+ZSQRPwhRdj2c8pgzgQEgU9606	intact-crc:4C8BAC7C40F38F93|rigid:fhiRJoyr4rywf7SGXu49Lkvvevg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2A8L8E9	uniprotkb:Q9UPN3	intact:EBI-2830125|uniprotkb:Q6KQE7|uniprotkb:Q6HW96|uniprotkb:E9R0K9|uniprotkb:E9R0L0|uniprotkb:Q81N36|uniprotkb:A0A1J9X5U0	intact:EBI-522925|uniprotkb:E9PJT0|uniprotkb:O75053|uniprotkb:Q5VW20|uniprotkb:Q8WXY2|uniprotkb:Q9H540|uniprotkb:Q9UKP0|uniprotkb:Q9ULG9|intact:EBI-28967632|uniprotkb:B1ALC5|uniprotkb:Q8WXY1|uniprotkb:Q96PK2	psi-mi:a0a2a8l8e9_bacan(display_long)|uniprotkb:GBAA_3381(locus name)	psi-mi:macf1_human(display_long)|uniprotkb:Actin cross-linking family protein 7(gene name synonym)|uniprotkb:Macrophin-1(gene name synonym)|uniprotkb:Trabeculin-alpha(gene name synonym)|uniprotkb:620 kDa actin-binding protein(gene name synonym)|uniprotkb:MACF1(gene name)|psi-mi:MACF1(display_short)|uniprotkb:ABP620(gene name synonym)|uniprotkb:ACF7(gene name synonym)|uniprotkb:KIAA0465(gene name synonym)|uniprotkb:KIAA1251(gene name synonym)|uniprotkb:KIAA0754(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830130|imex:IM-13779-3384	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR009711(Protein of unknown function DUF1292)	"go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0010632""(regulation of epithelial cell migration)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032886""(regulation of microtubule-based process)|go:""GO:0042060""(wound healing)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0051011""(microtubule minus-end binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0150011""(regulation of neuron projection arborization)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|interpro:IPR049538|mint:Q9UPN3|rcsb pdb:4Z6G|rcsb pdb:5VE9|rcsb pdb:5X57|refseq:NP_036222.3|efo:""Orphanet:572013""|dip:DIP-50616N|panther:PTHR23169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:n2zcNkvgLJPvCZKOqy8n3vIg8ew1392	rogid:G5PesqPZZxQhwDgW0pBJSkJNcZ49606	intact-crc:974FE4C8ABF56452|rigid:WtDjceuQTwbf7ExQ3f7w+ckz+mY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P8Q0	uniprotkb:O95819	intact:EBI-2830161|uniprotkb:Q6HV82|uniprotkb:Q6KPF4|uniprotkb:E9QTZ7|uniprotkb:E9QTZ8|uniprotkb:Q81XY5|uniprotkb:A0A0F7RFB5	intact:EBI-2511133|intact:EBI-28985706|uniprotkb:O75172|uniprotkb:Q9NST7|uniprotkb:E7ESS2|ensembl:ENSP00000314363.6	psi-mi:a0a6l8p8q0_bacan(display_long)|uniprotkb:GBAA_3779(locus name)	psi-mi:m4k4_human(display_long)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830166|imex:IM-13779-3391	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000172077.1	"refseq:NP_663719.2|refseq:NP_001229488.1|refseq:NP_004825.3|refseq:NP_663720.1|ensembl:ENSG00000071054.17(gene)|ensembl:ENST00000347699.8(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001953""(negative regulation of cell-matrix adhesion)|go:""GO:0004111""(creatine kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008017""(microtubule binding)|go:""GO:0008349""(MAP kinase kinase kinase kinase activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0032014""(positive regulation of ARF protein signal transduction)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046328""(regulation of JNK cascade)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0120183""(positive regulation of focal adhesion disassembly)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR051700|mint:O95819|rcsb pdb:4OBO|rcsb pdb:4OBP|rcsb pdb:4OBQ|rcsb pdb:4RVT|rcsb pdb:4U3Y|rcsb pdb:4U3Z|rcsb pdb:4U40|rcsb pdb:4U41|rcsb pdb:4U42|rcsb pdb:4U43|rcsb pdb:4U44|rcsb pdb:4U45|rcsb pdb:4ZK5|rcsb pdb:4ZP5|rcsb pdb:5DI1|rcsb pdb:5J95|rcsb pdb:5W5Q|reactome:R-HSA-2559580|panther:PTHR48015(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kX6YIq+2v84YwXZQBIK49NpDYSc1392	rogid:wEXGp6vM4HhwldyeQJKvEdilMpQ9606	intact-crc:F1EBA97B4A44BA16|rigid:oCEb4+Xn30rsTr5pDtRaXJzg5Us	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NUY8	uniprotkb:Q9UPN3	intact:EBI-2830152|uniprotkb:Q6KUM5|uniprotkb:Q6I0R9|uniprotkb:E9R9Y7|uniprotkb:E9R9Y8|uniprotkb:Q81SI6|uniprotkb:A0A0F7RJW0	intact:EBI-522925|uniprotkb:E9PJT0|uniprotkb:O75053|uniprotkb:Q5VW20|uniprotkb:Q8WXY2|uniprotkb:Q9H540|uniprotkb:Q9UKP0|uniprotkb:Q9ULG9|intact:EBI-28967632|uniprotkb:B1ALC5|uniprotkb:Q8WXY1|uniprotkb:Q96PK2	psi-mi:a0a6l8nuy8_bacan(display_long)|uniprotkb:GBAA_1663(locus name)	psi-mi:macf1_human(display_long)|uniprotkb:Actin cross-linking family protein 7(gene name synonym)|uniprotkb:Macrophin-1(gene name synonym)|uniprotkb:Trabeculin-alpha(gene name synonym)|uniprotkb:620 kDa actin-binding protein(gene name synonym)|uniprotkb:MACF1(gene name)|psi-mi:MACF1(display_short)|uniprotkb:ABP620(gene name synonym)|uniprotkb:ACF7(gene name synonym)|uniprotkb:KIAA0465(gene name synonym)|uniprotkb:KIAA1251(gene name synonym)|uniprotkb:KIAA0754(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830149|imex:IM-13779-3388	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000800095.1	"go:""GO:0003723""(RNA binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0010632""(regulation of epithelial cell migration)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032886""(regulation of microtubule-based process)|go:""GO:0042060""(wound healing)|go:""GO:0043001""(Golgi to plasma membrane protein transport)|go:""GO:0045104""(intermediate filament cytoskeleton organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0045773""(positive regulation of axon extension)|go:""GO:0051011""(microtubule minus-end binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0150011""(regulation of neuron projection arborization)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|interpro:IPR049538|mint:Q9UPN3|rcsb pdb:4Z6G|rcsb pdb:5VE9|rcsb pdb:5X57|refseq:NP_036222.3|efo:""Orphanet:572013""|dip:DIP-50616N|panther:PTHR23169(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gCOeQmpj7bQCNRtg3IzBjtdhKO01392	rogid:G5PesqPZZxQhwDgW0pBJSkJNcZ49606	intact-crc:E542758FECFFD98C|rigid:u825gNuAc/NoR4AwNkliQij4CmU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VT3	uniprotkb:Q92918	intact:EBI-2816582|uniprotkb:Q6KYI3|uniprotkb:Q6I4T7	intact:EBI-881|intact:EBI-28975476|ensembl:ENSP00000465039.1	psi-mi:efg_bacan(display_long)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)|uniprotkb:BA_0107(locus name)|uniprotkb:GBAA_0107(locus name)|uniprotkb:BAS0107(locus name)	psi-mi:m4k1_human(display_long)|uniprotkb:HPK1(gene name synonym)|uniprotkb:MAP4K1(gene name)|psi-mi:MAP4K1(display_short)|uniprotkb:MAPK/ERK kinase kinase kinase 1(gene name synonym)|uniprotkb:Hematopoietic progenitor kinase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830180|imex:IM-13779-3390	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR031157|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|refseq:WP_000090364.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|refseq:NP_842675.1|refseq:YP_026393.1|interpro:IPR047872"	"refseq:NP_009112.1|refseq:NP_001036065.1|dip:DIP-31019N|panther:PTHR48012(orthology-group)|ensembl:ENSG00000104814.13(gene)|ensembl:ENST00000591517.5(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007254""(JNK cascade)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008349""(MAP kinase kinase kinase kinase activity)|go:""GO:0016020""(membrane)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1904628""(cellular response to phorbol 13-acetate 12-myristate)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR021160|interpro:IPR050629|mint:Q92918|rcsb pdb:6CQD|rcsb pdb:6CQE|rcsb pdb:6CQF|rcsb pdb:6NFY|rcsb pdb:6NFZ|rcsb pdb:6NG0|rcsb pdb:7KAC|rcsb pdb:7L24|rcsb pdb:7L25|rcsb pdb:7L26|rcsb pdb:7M0K|rcsb pdb:7M0L|rcsb pdb:7M0M|rcsb pdb:7R9L|rcsb pdb:7R9N|rcsb pdb:7R9P|rcsb pdb:7R9T|rcsb pdb:7SIU|rcsb pdb:8CDW|rcsb pdb:8CIJ|rcsb pdb:8EEC|rcsb pdb:8FH4|rcsb pdb:8FJZ|rcsb pdb:8FKO|rcsb pdb:8PAR|rcsb pdb:8PAS|rcsb pdb:8PAU|rcsb pdb:8XN7|rcsb pdb:9BI8|rcsb pdb:9BIK|rcsb pdb:9BJ1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iKao5O7KH1KI6bGoVf+7AT6g3181392	rogid:XAnNUBaT7pFyJMbz5gbC1ahCono9606	intact-crc:D0B95B019A57471D|rigid:YhjfiE695A0KzIJy+qiZPIB3kds	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92918	uniprotkb:A0A6H3AKP3	intact:EBI-881|intact:EBI-28975476|ensembl:ENSP00000465039.1	intact:EBI-2813310|uniprotkb:Q6KM94|uniprotkb:Q6HT04|uniprotkb:E9QTN5|uniprotkb:E9QTN6|uniprotkb:Q81LJ8|uniprotkb:A0A1V4BJH0	psi-mi:m4k1_human(display_long)|uniprotkb:HPK1(gene name synonym)|uniprotkb:MAP4K1(gene name)|psi-mi:MAP4K1(display_short)|uniprotkb:MAPK/ERK kinase kinase kinase 1(gene name synonym)|uniprotkb:Hematopoietic progenitor kinase(gene name synonym)	psi-mi:a0a6h3akp3_bacan(display_long)|uniprotkb:GBAA_4618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830173|imex:IM-13779-3389	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009112.1|refseq:NP_001036065.1|dip:DIP-31019N|panther:PTHR48012(orthology-group)|ensembl:ENSG00000104814.13(gene)|ensembl:ENST00000591517.5(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007254""(JNK cascade)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008349""(MAP kinase kinase kinase kinase activity)|go:""GO:0016020""(membrane)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1904628""(cellular response to phorbol 13-acetate 12-myristate)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR021160|interpro:IPR050629|mint:Q92918|rcsb pdb:6CQD|rcsb pdb:6CQE|rcsb pdb:6CQF|rcsb pdb:6NFY|rcsb pdb:6NFZ|rcsb pdb:6NG0|rcsb pdb:7KAC|rcsb pdb:7L24|rcsb pdb:7L25|rcsb pdb:7L26|rcsb pdb:7M0K|rcsb pdb:7M0L|rcsb pdb:7M0M|rcsb pdb:7R9L|rcsb pdb:7R9N|rcsb pdb:7R9P|rcsb pdb:7R9T|rcsb pdb:7SIU|rcsb pdb:8CDW|rcsb pdb:8CIJ|rcsb pdb:8EEC|rcsb pdb:8FH4|rcsb pdb:8FJZ|rcsb pdb:8FKO|rcsb pdb:8PAR|rcsb pdb:8PAS|rcsb pdb:8PAU|rcsb pdb:8XN7|rcsb pdb:9BI8|rcsb pdb:9BIK|rcsb pdb:9BJ1"	"refseq:WP_000793108.1|interpro:IPR002549(Protein of unknown function UPF0118)|go:""GO:0016020""(membrane)|go:""GO:0055085""(transmembrane transport)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XAnNUBaT7pFyJMbz5gbC1ahCono9606	rogid:EuoKynuHXFv/xrmnc1nvaUXmtMM1392	intact-crc:B6250BFD274F6A52|rigid:Hej5EWmyKFlh+mxZDVOzfUOB9jo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1WE58	uniprotkb:P41279	intact:EBI-2810305|uniprotkb:Q6KW20|uniprotkb:Q6I285|uniprotkb:E9R1F6|uniprotkb:E9R1F7|uniprotkb:A0A2P0HB60|uniprotkb:Q81U00	intact:EBI-354900|uniprotkb:Q14275|uniprotkb:Q5T855|uniprotkb:Q9HC81|uniprotkb:A8K2Q5|uniprotkb:D3DRX1|ensembl:ENSP00000263056.1|ensembl:ENSP00000364470.1|ensembl:ENSP00000443610.1	psi-mi:a0a4y1we58_bacan(display_long)|uniprotkb:GBAA_1094(locus name)	psi-mi:m3k8_human(display_long)|uniprotkb:MAP3K8(gene name)|psi-mi:MAP3K8(display_short)|uniprotkb:COT(gene name synonym)|uniprotkb:ESTF(gene name synonym)|uniprotkb:Serine/threonine-protein kinase cot(gene name synonym)|uniprotkb:Cancer Osaka thyroid oncogene(gene name synonym)|uniprotkb:Tumor progression locus 2(gene name synonym)|uniprotkb:Proto-oncogene c-Cot(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830187|imex:IM-13779-3392	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020968|interpro:IPR008979(Galactose-binding like)|interpro:IPR022385|interpro:IPR006530(YD repeat)|interpro:IPR050708|go:""GO:0016020""(membrane)|refseq:WP_000387561.1|interpro:IPR045351|interpro:IPR031325"	"refseq:NP_005195.2|refseq:NP_001231063.1|ensembl:ENSG00000107968.10(gene)|ensembl:ENST00000263056.6(transcript)|ensembl:ENST00000375321.1(transcript)|ensembl:ENST00000542547.5(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0031295""(T cell costimulation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0106310""(protein serine kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017424(Mitogen-activated protein kinase kinase kinase 8)|interpro:IPR050538|mint:P41279|rcsb pdb:4Y83|rcsb pdb:4Y85|rcsb pdb:5IU2|reactome:R-HSA-389357|reactome:R-HSA-5684264|refseq:NP_001307890.1|refseq:XP_016871196.1|refseq:XP_016871197.1|refseq:XP_016871198.1|refseq:XP_016871199.1|dip:DIP-27534N|panther:PTHR48016(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8jqYn7kracNCDGYibTeEcZe2fl81392	rogid:jioNJRDtKJU8iwI+dNq4JSEHRoI9606	intact-crc:2F9BA067B5214195|rigid:LhH40chERM5seFBp6SLPbrvuufk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P10253	uniprotkb:A0A6L8PGF9	intact:EBI-2830238|uniprotkb:Q8IWE7|uniprotkb:Q09GN4|uniprotkb:Q16302|uniprotkb:Q14351|ensembl:ENSP00000305692.3|ensembl:ENSP00000374665.3|ensembl:ENSP00000458306.2|ensembl:ENSP00000460543.2|ensembl:ENSP00000516980.1|ensembl:ENSP00000516982.1|ensembl:ENSP00000519347.1|ensembl:ENSP00000519348.1	intact:EBI-2812067|uniprotkb:Q6HZF5|uniprotkb:Q6KTE4|uniprotkb:E9R4G8|uniprotkb:E9R4G9|uniprotkb:Q81R82|uniprotkb:A0A0F7RIG7	psi-mi:lyag_human(display_long)|uniprotkb:GAA(gene name)|psi-mi:GAA(display_short)|uniprotkb:Acid maltase(gene name synonym)|uniprotkb:Aglucosidase alfa(gene name synonym)	psi-mi:a0a6l8pgf9_bacan(display_long)|uniprotkb:GBAA_2174(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830235|imex:IM-13779-3395	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:308552""|efo:""Orphanet:420429""|ensembl:ENSG00000171298.15(gene)|ensembl:ENSG00000291507.1(gene)|ensembl:ENST00000302262.8(transcript)|ensembl:ENST00000390015.7(transcript)|ensembl:ENST00000570803.6(transcript)|ensembl:ENST00000577106.6(transcript)|ensembl:ENST00000707779.1(transcript)|ensembl:ENST00000707781.1(transcript)|ensembl:ENST00000714057.1(transcript)|ensembl:ENST00000714058.1(transcript)|go:""GO:0000023""(maltose metabolic process)|go:""GO:0002026""(regulation of the force of heart contraction)|go:""GO:0002086""(diaphragm contraction)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0004558""(alpha-1,4-glucosidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005980""(glycogen catabolic process)|go:""GO:0005985""(sucrose metabolic process)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0007040""(lysosome organization)|go:""GO:0007626""(locomotory behavior)|go:""GO:0009888""(tissue development)|go:""GO:0016020""(membrane)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035904""(aorta development)|go:""GO:0043181""(vacuolar sequestering)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0050884""(neuromuscular process controlling posture)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0060048""(cardiac muscle contraction)|go:""GO:0061723""(glycophagy)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0090599""(alpha-glucosidase activity)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0120282""(autolysosome lumen)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR000519(P-type trefoil)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017957|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|interpro:IPR044913|interpro:IPR048395|mint:P10253|rcsb pdb:5KZW|rcsb pdb:5KZX|rcsb pdb:5NN3|rcsb pdb:5NN4|rcsb pdb:5NN5|rcsb pdb:5NN6|rcsb pdb:5NN8|rcsb pdb:7P2Z|rcsb pdb:7P32|reactome:R-HSA-5357609|reactome:R-HSA-6798695|reactome:R-HSA-70221|refseq:NP_000143.2|refseq:NP_001073271.1|refseq:NP_001073272.1|refseq:XP_005257250.1|refseq:XP_005257251.1|panther:PTHR22762(orthology-group)"	"interpro:IPR007536(Protein of unknown function DUF548)|interpro:IPR029063|go:""GO:0008990""(""rRNA (guanine-N2-)-methyltransferase activity"")|refseq:WP_000637445.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LqHRnythO4WRf8H74OqWoImqZJA9606	rogid:9J88Y78eGq6GLkPj6dvcpx+fMzY1392	intact-crc:0F2420173C44778A|rigid:UcaPFkHgTmO1FzRtrKLGFD6e2yU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P61626	uniprotkb:Q81X77	intact:EBI-355360|uniprotkb:P00695|uniprotkb:Q9UCF8|uniprotkb:Q13170|ensembl:ENSP00000261267.2	intact:EBI-2810439|uniprotkb:Q6HR13|uniprotkb:Q6KKD2	psi-mi:lysc_human(display_long)|uniprotkb:LYZ(gene name)|psi-mi:LYZ(display_short)|uniprotkb:LZM(gene name synonym)|uniprotkb:1,4-beta-N-acetylmuramidase C(gene name synonym)	psi-mi:gpmi_bacan(display_long)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)|uniprotkb:gpmA(gene name synonym)|uniprotkb:BA_5365(locus name)|uniprotkb:GBAA_5365(locus name)|uniprotkb:BAS4986(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830228|imex:IM-13779-3393	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090382.7(gene)|ensembl:ENST00000261267.7(transcript)|go:""GO:0003796""(lysozyme activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006954""(inflammatory response)|go:""GO:0019730""(antimicrobial humoral response)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904724""(tertiary granule lumen)|interpro:IPR000974(Glycoside hydrolase, family 22, lysozyme)|interpro:IPR001916(Glycoside hydrolase, family 22)|interpro:IPR019799|interpro:IPR023346|mint:P61626|rcsb pdb:133L|rcsb pdb:134L|rcsb pdb:1B5U|rcsb pdb:1B5V|rcsb pdb:1B5W|rcsb pdb:1B5X|rcsb pdb:1B5Y|rcsb pdb:1B5Z|rcsb pdb:1B7L|rcsb pdb:1B7M|rcsb pdb:1B7N|rcsb pdb:1B7O|rcsb pdb:1B7P|rcsb pdb:1B7Q|rcsb pdb:1B7R|rcsb pdb:1B7S|rcsb pdb:1BB3|rcsb pdb:1BB4|rcsb pdb:1BB5|rcsb pdb:1C43|rcsb pdb:1C45|rcsb pdb:1C46|rcsb pdb:1C7P|rcsb pdb:1CJ6|rcsb pdb:1CJ7|rcsb pdb:1CJ8|rcsb pdb:1CJ9|rcsb pdb:1CKC|rcsb pdb:1CKD|rcsb pdb:1CKF|rcsb pdb:1CKG|rcsb pdb:1CKH|rcsb pdb:1D6P|rcsb pdb:1D6Q|rcsb pdb:1DI3|rcsb pdb:1DI4|rcsb pdb:1DI5|rcsb pdb:1EQ4|rcsb pdb:1EQ5|rcsb pdb:1EQE|rcsb pdb:1GAY|rcsb pdb:1GAZ|rcsb pdb:1GB0|rcsb pdb:1GB2|rcsb pdb:1GB3|rcsb pdb:1GB5|rcsb pdb:1GB6|rcsb pdb:1GB7|rcsb pdb:1GB8|rcsb pdb:1GB9|rcsb pdb:1GBO|rcsb pdb:1GBW|rcsb pdb:1GBX|rcsb pdb:1GBY|rcsb pdb:1GBZ|rcsb pdb:1GDW|rcsb pdb:1GDX|rcsb pdb:1GE0|rcsb pdb:1GE1|rcsb pdb:1GE2|rcsb pdb:1GE3|rcsb pdb:1GE4|rcsb pdb:1GEV|rcsb pdb:1GEZ|rcsb pdb:1GF0|rcsb pdb:1GF3|rcsb pdb:1GF4|rcsb pdb:1GF5|rcsb pdb:1GF6|rcsb pdb:1GF7|rcsb pdb:1GF8|rcsb pdb:1GF9|rcsb pdb:1GFA|rcsb pdb:1GFE|rcsb pdb:1GFG|rcsb pdb:1GFH|rcsb pdb:1GFJ|rcsb pdb:1GFK|rcsb pdb:1GFR|rcsb pdb:1GFT|rcsb pdb:1GFU|rcsb pdb:1GFV|rcsb pdb:1HNL|rcsb pdb:1I1Z|rcsb pdb:1I20|rcsb pdb:1I22|rcsb pdb:1INU|rcsb pdb:1IOC|rcsb pdb:1IP1|rcsb pdb:1IP2|rcsb pdb:1IP3|rcsb pdb:1IP4|rcsb pdb:1IP5|rcsb pdb:1IP6|rcsb pdb:1IP7|rcsb pdb:1IWT|rcsb pdb:1IWU|rcsb pdb:1IWV|rcsb pdb:1IWW|rcsb pdb:1IWX|rcsb pdb:1IWY|rcsb pdb:1IWZ|rcsb pdb:1IX0|rcsb pdb:1IY3|rcsb pdb:1IY4|rcsb pdb:1JKA|rcsb pdb:1JKB|rcsb pdb:1JKC|rcsb pdb:1JKD|rcsb pdb:1JSF|rcsb pdb:1JWR|rcsb pdb:1LAA|rcsb pdb:1LHH|rcsb pdb:1LHI|rcsb pdb:1LHJ|rcsb pdb:1LHK|rcsb pdb:1LHL|rcsb pdb:1LHM|rcsb pdb:1LMT|rcsb pdb:1LOZ|rcsb pdb:1LYY|rcsb pdb:1LZ1|rcsb pdb:1LZ4|rcsb pdb:1LZ5|rcsb pdb:1LZ6|rcsb pdb:1LZR|rcsb pdb:1LZS|rcsb pdb:1OP9|rcsb pdb:1OUA|rcsb pdb:1OUB|rcsb pdb:1OUC|rcsb pdb:1OUD|rcsb pdb:1OUE|rcsb pdb:1OUF|rcsb pdb:1OUG|rcsb pdb:1OUH|rcsb pdb:1OUI|rcsb pdb:1OUJ|rcsb pdb:1QSW|rcsb pdb:1RE2|rcsb pdb:1REM|rcsb pdb:1REX|rcsb pdb:1REY|rcsb pdb:1REZ|rcsb pdb:1TAY|rcsb pdb:1TBY|rcsb pdb:1TCY|rcsb pdb:1TDY|rcsb pdb:1UBZ|rcsb pdb:1W08|rcsb pdb:1WQM|rcsb pdb:1WQN|rcsb pdb:1WQO|rcsb pdb:1WQP|rcsb pdb:1WQQ|rcsb pdb:1WQR|rcsb pdb:1YAM|rcsb pdb:1YAN|rcsb pdb:1YAO|rcsb pdb:1YAP|rcsb pdb:1YAQ|rcsb pdb:207L|rcsb pdb:208L|rcsb pdb:2BQA|rcsb pdb:2BQB|rcsb pdb:2BQC|rcsb pdb:2BQD|rcsb pdb:2BQE|rcsb pdb:2BQF|rcsb pdb:2BQG|rcsb pdb:2BQH|rcsb pdb:2BQI|rcsb pdb:2BQJ|rcsb pdb:2BQK|rcsb pdb:2BQL|rcsb pdb:2BQM|rcsb pdb:2BQN|rcsb pdb:2BQO|rcsb pdb:2HEA|rcsb pdb:2HEB|rcsb pdb:2HEC|rcsb pdb:2HED|rcsb pdb:2HEE|rcsb pdb:2HEF|rcsb pdb:2LHM|rcsb pdb:2MEA|rcsb pdb:2MEB|rcsb pdb:2MEC|rcsb pdb:2MED|rcsb pdb:2MEE|rcsb pdb:2MEF|rcsb pdb:2MEG|rcsb pdb:2MEH|rcsb pdb:2MEI|rcsb pdb:2NWD|rcsb pdb:2ZIJ|rcsb pdb:2ZIK|rcsb pdb:2ZIL|rcsb pdb:2ZWB|rcsb pdb:3EBA|rcsb pdb:3FE0|rcsb pdb:3LHM|rcsb pdb:3LN2|rcsb pdb:4I0C|rcsb pdb:4ML7|rcsb pdb:4R0P|rcsb pdb:5LSH|rcsb pdb:5LVK|rcsb pdb:6LFH|rcsb pdb:7AP7|rcsb pdb:7XF6|rcsb pdb:7XF7|rcsb pdb:7XF8|rcsb pdb:8QUT|reactome:R-HSA-6798695|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_000230.1|efo:""Orphanet:93561""|panther:PTHR11407(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|rcsb pdb:2IFY|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030435""(sporulation resulting in formation of a cellular spore)|go:""GO:0043937""(regulation of sporulation)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|refseq:WP_001231153.1|interpro:IPR036646|refseq:NP_847539.1|refseq:YP_031225.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jydNN9yuU9EYvnth+kv115svRxw9606	rogid:pxX2Dycc6/EBhmFHPZ5uVcHE6I41392	intact-crc:4B5C787D16B4E563|rigid:SJMHc3gCI9ybv/vWY2NQTORGUgc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H121	uniprotkb:Q99698	intact:EBI-2812162|uniprotkb:Q6KPC5|uniprotkb:Q6HV53|uniprotkb:E9QR13|uniprotkb:E9QR14|uniprotkb:Q81XV4|uniprotkb:A0A0F7RA44	intact:EBI-2830208|uniprotkb:Q5T2U9|uniprotkb:O43274|uniprotkb:Q96TD8|uniprotkb:Q96TD7|uniprotkb:Q9H133|uniprotkb:Q99709|ensembl:ENSP00000374443.2	psi-mi:a0a6l7h121_bacan(display_long)|uniprotkb:GBAA_3814(locus name)	psi-mi:lyst_human(display_long)|uniprotkb:LYST(gene name)|psi-mi:LYST(display_short)|uniprotkb:CHS(gene name synonym)|uniprotkb:CHS1(gene name synonym)|uniprotkb:Beige homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830221|imex:IM-13779-3396	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR050750|interpro:IPR029063|go:""GO:0009307""(DNA restriction-modification system)|go:""GO:0032259""(methylation)|go:""GO:0051719""(""DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates"")|go:""GO:0051720""(""DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates"")|refseq:WP_000286272.1"	"efo:""Orphanet:167""|efo:""Orphanet:352723""|ensembl:ENSG00000143669.16(gene)|ensembl:ENST00000389793.7(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006909""(phagocytosis)|go:""GO:0008104""(protein localization)|go:""GO:0015031""(protein transport)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030595""(leukocyte chemotaxis)|go:""GO:0032438""(melanosome organization)|go:""GO:0032510""(endosome to lysosome transport via multivesicular body sorting pathway)|go:""GO:0033364""(mast cell secretory granule organization)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042832""(defense response to protozoan)|go:""GO:0043473""(pigmentation)|go:""GO:0051607""(defense response to virus)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019775|interpro:IPR023362|interpro:IPR036322|interpro:IPR036372|interpro:IPR050865|mint:Q99698|refseq:NP_000072.2|refseq:NP_001288294.1|panther:PTHR13743(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hfAwL7rY7VEKa5dCSgNFS9MoDfw1392	rogid:vO+yDuFmFJ9TEmQ7JeUpni4mguY9606	intact-crc:49C2833FB719F694|rigid:/3NKCX4uNpgfhFzAWlo70qvk8oY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12852	uniprotkb:Q6KNA9	intact:EBI-710223|uniprotkb:Q86VQ5|uniprotkb:Q8WY25|uniprotkb:B3KSS9|uniprotkb:G3V1Y2|ensembl:ENSP00000267079.2	intact:EBI-2812936|uniprotkb:Q6HU26|uniprotkb:Q81MM9	psi-mi:m3k12_human(display_long)|uniprotkb:Mixed lineage kinase(gene name synonym)|uniprotkb:Leucine-zipper protein kinase(gene name synonym)|uniprotkb:Dual leucine zipper bearing kinase(gene name synonym)|uniprotkb:MAPK-upstream kinase(gene name synonym)|uniprotkb:MAP3K12(gene name)|psi-mi:MAP3K12(display_short)|uniprotkb:ZPK(gene name synonym)	psi-mi:mete_bacan(display_long)|uniprotkb:metE(gene name)|psi-mi:metE(display_short)|uniprotkb:Cobalamin-independent methionine synthase(gene name synonym)|uniprotkb:Methionine synthase, vitamin-B12 independent isozyme(gene name synonym)|uniprotkb:BA_4218(locus name)|uniprotkb:GBAA_4218(locus name)|uniprotkb:BAS3912(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830201|imex:IM-13779-3394	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011537027.1|refseq:NP_001180440.1|refseq:NP_006292.3|refseq:XP_005269195.1|refseq:XP_006719651.1|refseq:XP_016875445.1|ensembl:ENSG00000139625.13(gene)|ensembl:ENST00000267079.6(transcript)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007254""(JNK cascade)|go:""GO:0016020""(membrane)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030426""(growth cone)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043507""(positive regulation of JUN kinase activity)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0043687""(post-translational protein modification)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:2000672""(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017419(Mitogen-activated protein kinase kinase kinase, 12/13)|interpro:IPR027257|interpro:IPR051681|mint:Q12852|rcsb pdb:5CEN|rcsb pdb:5CEO|rcsb pdb:5CEP|rcsb pdb:5CEQ|rcsb pdb:5VO1|rcsb pdb:5VO2|rcsb pdb:8DEG|rcsb pdb:8OUR|rcsb pdb:8OUS|rcsb pdb:8OUT|panther:PTHR44329(orthology-group)"	"refseq:WP_001007635.1|interpro:IPR013215(""Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal"")|interpro:IPR006276(5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase)|interpro:IPR002629(Methionine synthase, vitamin-B12 independent)|go:""GO:0003871""(5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0032259""(methylation)|interpro:IPR038071|refseq:NP_846453.1|refseq:YP_030162.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:z8bh1eVLo2OCPlPYIoGG7sk+mmw9606	rogid:zrEJnY1x7+9Q1u7iaM9JmIvFVAQ1392	intact-crc:241443AB717D6D60|rigid:6wChc9xkAJsR4ZCREVhHF/qUQ5Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HJC6	uniprotkb:O95382	intact:EBI-2820663|uniprotkb:Q6HZ80|uniprotkb:Q6KT73|uniprotkb:E9QZP4|uniprotkb:E9QZP5|uniprotkb:Q81R09|uniprotkb:A0A1S0QN45|uniprotkb:A0A2P0HDW8	intact:EBI-1254761|uniprotkb:Q5SSD4|uniprotkb:A2ACE8|uniprotkb:A2VDG4|uniprotkb:A2VDG5|uniprotkb:Q59HF4|uniprotkb:Q75PK3|uniprotkb:Q96B75|ensembl:ENSP00000350195.2	psi-mi:a0a6l7hjc6_bacan(display_long)|uniprotkb:GBAA_2251(locus name)|uniprotkb:asnO3(gene name)|psi-mi:asnO3(display_short)	psi-mi:m3k6_human(display_long)|uniprotkb:MAP3K6(gene name)|psi-mi:MAP3K6(display_short)|uniprotkb:MAPKKK6(gene name synonym)|uniprotkb:ASK2(gene name synonym)|uniprotkb:MEKK6(gene name synonym)|uniprotkb:Apoptosis signal-regulating kinase 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830194|imex:IM-13779-3397	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR001962(Asparagine synthase)|interpro:IPR017932|interpro:IPR033738|interpro:IPR029055|go:""GO:0004066""(""asparagine synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006529""(asparagine biosynthetic process)|interpro:IPR051786|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:WP_000333816.1"	"efo:""Orphanet:26106""|ensembl:ENSG00000142733.18(gene)|ensembl:ENST00000357582.3(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004706""(JUN kinase kinase kinase activity)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007165""(signal transduction)|go:""GO:0007254""(JNK cascade)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0106310""(protein serine kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR025136|interpro:IPR043969|interpro:IPR046872|interpro:IPR046873|mint:O95382|refseq:NP_001284538.1|refseq:NP_004663.3|panther:PTHR11584(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WTdgXI+311I0qC/oeld/7wVHnps1392	rogid:aBgwpbMlD+zqwols3+CiNiOARVo9606	intact-crc:74373057695911DE|rigid:v3VBsHlqtoL8UhGTx9MTEg5PC+s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H1G2	uniprotkb:Q8N2S1	intact:EBI-2809927	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905.8	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830271|imex:IM-13779-3402	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"ensembl:ENSG00000090006.18(gene)|ensembl:ENST00000308370.11(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006457""(protein folding)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031012""(extracellular matrix)|go:""GO:0046879""(hormone secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q8N2S1|reactome:R-HSA-2129379|reactome:R-HSA-2173789|refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|efo:""Orphanet:221145""|efo:""Orphanet:98896""|panther:PTHR24034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	intact-crc:8454512992FEC236|rigid:CJzpH0fvc/IK+y2Po7e4o7JKQcU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2P0HHU3	uniprotkb:O15116	intact:EBI-2811119|uniprotkb:Q6KPA1|uniprotkb:E9RCY6|uniprotkb:Q81WX2	intact:EBI-347619|ensembl:ENSP00000310596.4|uniprotkb:B2R5E6	psi-mi:a0a2p0hhu3_bacan(display_long)|uniprotkb:GBAA_3841(locus name)	psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830278|imex:IM-13779-3400	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|go:""GO:0005615""(extracellular space)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|refseq:WP_000092465.1|interpro:IPR048009"	"ensembl:ENSG00000175324.10(gene)|ensembl:ENST00000311351.9(transcript)|go:""GO:0000290""(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:""GO:0000375""(RNA splicing, via transesterification reactions)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:1990726""(Lsm1-7-Pat1 complex)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|interpro:IPR047575|mint:O15116|reactome:R-HSA-430039|refseq:NP_055277.1|dip:DIP-31130N|panther:PTHR15588(orthology-group)|ensembl:ENSP00000310596.4"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/09	rogid:bOpkW2SnpXGvNsOHSbPKRkQYwxw1392	rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606	intact-crc:9206514FD0B5C473|rigid:TKStxiaerQk2mSgI/1ideOlXjf8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N2S1	uniprotkb:A0A6L8NYD9	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905.8	intact:EBI-2818228|uniprotkb:Q6KW27|uniprotkb:E9QS09|uniprotkb:Q81U08	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	psi-mi:a0a6l8nyd9_bacan(display_long)|uniprotkb:GBAA_1086(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830250|imex:IM-13779-3398	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000090006.18(gene)|ensembl:ENST00000308370.11(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006457""(protein folding)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031012""(extracellular matrix)|go:""GO:0046879""(hormone secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q8N2S1|reactome:R-HSA-2129379|reactome:R-HSA-2173789|refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|efo:""Orphanet:221145""|efo:""Orphanet:98896""|panther:PTHR24034(orthology-group)"	"interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR001761(Periplasmic binding protein/LacI transcriptional regulator)|interpro:IPR000843(Bacterial regulatory protein, LacI)|interpro:IPR028082|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|refseq:WP_000103719.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	rogid:kmo4fq/IG0KTUNsqv5GR7zI4ZZE1392	intact-crc:C00D4F454B3B1310|rigid:KCQHe4B1ea/+62NcKsEFihHoCIQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2P0H9B7	uniprotkb:Q8N2S1	intact:EBI-2814623|uniprotkb:Q6KXX3|uniprotkb:E9QUQ6|uniprotkb:Q81ZC1	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905.8	psi-mi:a0a2p0h9b7_bacan(display_long)|uniprotkb:GBAA_0348(locus name)	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830264|imex:IM-13779-3399	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000926544.1|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR050197|go:""GO:0005829""(cytosol)|go:""GO:0016832""(aldehyde-lyase activity)|go:""GO:0019323""(pentose catabolic process)|interpro:IPR036409"	"ensembl:ENSG00000090006.18(gene)|ensembl:ENST00000308370.11(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006457""(protein folding)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031012""(extracellular matrix)|go:""GO:0046879""(hormone secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q8N2S1|reactome:R-HSA-2129379|reactome:R-HSA-2173789|refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|efo:""Orphanet:221145""|efo:""Orphanet:98896""|panther:PTHR24034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lknloEA+ybxoXR7fhScia5vFhmc1392	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	intact-crc:38C80DDC2B0D4044|rigid:jLBOQvzuDm7dlmuXpdBSwfqZ4Wg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81TK1	uniprotkb:Q8N2S1	intact:EBI-2819816|uniprotkb:Q6KVM3|uniprotkb:Q6I1T3	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905.8	psi-mi:odo1_bacan(display_long)|uniprotkb:odhA(gene name)|psi-mi:odhA(display_short)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:BA_1270(locus name)|uniprotkb:GBAA_1270(locus name)|uniprotkb:BAS1177(locus name)	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830257|imex:IM-13779-3401	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR023784|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR029061|go:""GO:0004591""(""oxoglutarate dehydrogenase (succinyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006096""(glycolytic process)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|refseq:WP_000197146.1|interpro:IPR031717|interpro:IPR042179|refseq:NP_843742.1|refseq:YP_027447.1"	"ensembl:ENSG00000090006.18(gene)|ensembl:ENST00000308370.11(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006457""(protein folding)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031012""(extracellular matrix)|go:""GO:0046879""(hormone secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q8N2S1|reactome:R-HSA-2129379|reactome:R-HSA-2173789|refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|efo:""Orphanet:221145""|efo:""Orphanet:98896""|panther:PTHR24034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8Loo3rMq41/Gg3LofhIbmnjb+1s1392	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	intact-crc:6F8C148839313DB8|rigid:bp7DOnwqncMi46XlZxYEFli+izE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95777	uniprotkb:Q81SB0	intact:EBI-347779|ensembl:ENSP00000249299.2	intact:EBI-2830299|uniprotkb:Q6KUF6|uniprotkb:E9R348	psi-mi:lsm8_human(display_long)|uniprotkb:LSM8(gene name)|psi-mi:LSM8(display_short)	psi-mi:q81sb0_bacan(display_long)|uniprotkb:GBAA_1755(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830296|imex:IM-13779-3403	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000128534.8(gene)|ensembl:ENST00000249299.7(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005688""(U6 snRNP)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071011""(precatalytic spliceosome)|go:""GO:0120115""(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034103|interpro:IPR044642|interpro:IPR047575|mint:O95777|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8QO9|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RM5|reactome:R-HSA-72163|refseq:NP_057284.1|dip:DIP-31195N|panther:PTHR15588(orthology-group)"	"interpro:IPR015943(WD40/YVTN repeat-like)|go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0010411""(xyloglucan metabolic process)|go:""GO:0016798""(hydrolase activity, acting on glycosyl bonds)|interpro:IPR052025"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/14	rogid:Kyf8IAEIkbe1s2NnqxqGA1o6BbU9606	rogid:HJFlIrh9gQtaZvHBFu/milTIS001392	intact-crc:8B6E0F7D4CF9A857|rigid:rxTX/P8wpuH/NSSy9rC8JKeOfAg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PGI4	uniprotkb:Q8N2S1	intact:EBI-2830288|uniprotkb:Q6KU86|uniprotkb:E9QX78|uniprotkb:Q81S35|uniprotkb:A0A0F7RG01	intact:EBI-947718|uniprotkb:O75412|uniprotkb:O75413|uniprotkb:O00508|ensembl:ENSP00000311905.8	psi-mi:a0a6l8pgi4_bacan(display_long)|uniprotkb:GBAA_1842(locus name)	psi-mi:ltbp4_human(display_long)|uniprotkb:LTBP4(gene name)|psi-mi:LTBP4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830285|imex:IM-13779-3406	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015815(3-hydroxyacid dehydrogenase/reductase)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|refseq:WP_000739168.1|interpro:IPR013328(Dehydrogenase, multihelical)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0050661""(NADP binding)|interpro:IPR036291|interpro:IPR051265|interpro:IPR048666"	"ensembl:ENSG00000090006.18(gene)|ensembl:ENST00000308370.11(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006457""(protein folding)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031012""(extracellular matrix)|go:""GO:0046879""(hormone secretion)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR036773|interpro:IPR049883|interpro:IPR050751|mint:Q8N2S1|reactome:R-HSA-2129379|reactome:R-HSA-2173789|refseq:NP_001036009.1|refseq:NP_001036010.1|refseq:NP_003564.2|efo:""Orphanet:221145""|efo:""Orphanet:98896""|panther:PTHR24034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dUIr2f3jJh6JCVP/oK5SXZr2ef41392	rogid:mBWo9asZp3rjkytgvTD+7OE5K5I9606	intact-crc:476D9584EDA30E90|rigid:ecYgNz2Q00l75aekgxjF+1GAS4U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81X31	uniprotkb:Q9Y608	intact:EBI-2823476|uniprotkb:Q6KK86|uniprotkb:E9RCY9	intact:EBI-1023718|uniprotkb:Q68CV3|uniprotkb:Q9NXH5|uniprotkb:A8K649|uniprotkb:A8MXR0|uniprotkb:B4DY63|ensembl:ENSP00000338727.4	psi-mi:q81x31_bacan(display_long)|uniprotkb:GBAA_5414(locus name)	psi-mi:lrrf2_human(display_long)|uniprotkb:LRRFIP2(gene name)|psi-mi:LRRFIP2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830328|imex:IM-13779-3408	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029045|interpro:IPR005151(Peptidase S41)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004447(Peptidase S41A, C-terminal protease)|interpro:IPR002477(Peptidoglycan binding-like)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0007165""(signal transduction)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|interpro:IPR055210|interpro:IPR036034|interpro:IPR036365|interpro:IPR036366"	"refseq:XP_011532519.1|refseq:XP_011532520.1|refseq:XP_011532521.1|refseq:XP_005265596.1|refseq:XP_005265597.1|refseq:NP_001335239.1|refseq:NP_001335240.1|refseq:NP_006300.1|refseq:NP_060194.1|refseq:NP_001127841.1|refseq:NP_001269620.1|refseq:XP_016862973.1|ensembl:ENSG00000093167.18(gene)|ensembl:ENST00000336686.9(transcript)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030275""(LRR domain binding)|interpro:IPR019139|mint:Q9Y608|panther:PTHR19212(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:plObfwnsvGD6eWNj60FiywaOafE1392	rogid:ma/crL7UY91uJ8bqLfkX3K8aQLI9606	intact-crc:64F3B0BFD30DE924|rigid:mHOXIVrisMRqsVG8PbJ7LPp5d+o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81XR1	uniprotkb:Q9BX40	intact:EBI-2829582|uniprotkb:Q6KKV5|uniprotkb:Q6HRI8	intact:EBI-715641|uniprotkb:Q6PFW8|uniprotkb:Q96LH8|ensembl:ENSP00000279068.5	psi-mi:y5172_bacan(display_long)|uniprotkb:BA_5172(locus name)|uniprotkb:GBAA_5172(locus name)|uniprotkb:BAS4807(locus name)	psi-mi:ls14b_human(display_long)|uniprotkb:LSM14B(gene name)|psi-mi:LSM14B(display_short)|uniprotkb:C20orf40(gene name synonym)|uniprotkb:FAM61B(gene name synonym)|uniprotkb:RAP55B(gene name synonym)|uniprotkb:RNA-associated protein 55B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830314|imex:IM-13779-3404	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR022916|interpro:IPR009910(Protein of unknown function DUF1450)|refseq:WP_000595026.1|refseq:NP_847355.1|refseq:YP_031050.1	"refseq:NP_653304.2|ensembl:ENSG00000149657.20(gene)|ensembl:ENST00000279068.11(transcript)|go:""GO:0001541""(ovarian follicle development)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0006417""(regulation of translation)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0048477""(oogenesis)|go:""GO:0140694""(membraneless organelle assembly)|go:""GO:0141065""(maternal mRNA clearance)|go:""GO:1903537""(meiotic cell cycle process involved in oocyte maturation)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|interpro:IPR047575|mint:Q9BX40|panther:PTHR13586(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jjkEEv3edo7Wp9aU9INQn6yhQik1392	rogid:Rjc2jC3AM1IT1rizdT6MdR+gycY9606	intact-crc:D6B51CDDB1B5F181|rigid:7m/dTTiudvr4fZbjUTuKn+GDkhM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ND56	uniprotkb:A0A6L8PG64	intact:EBI-1384320|uniprotkb:Q76LX7|uniprotkb:Q96AR3|uniprotkb:Q96K73|uniprotkb:Q96SN5|uniprotkb:Q9UFR3|intact:EBI-2563702|uniprotkb:B4DTG6|ensembl:ENSP00000413964.3|ensembl:ENSP00000459843.1	intact:EBI-2814435|uniprotkb:Q6HVL4|uniprotkb:Q6F097|uniprotkb:E9R0Y6|uniprotkb:E9R0Y7|uniprotkb:A0A2P0HH79|uniprotkb:Q81YC1	psi-mi:ls14a_human(display_long)|uniprotkb:C19orf13(gene name synonym)|uniprotkb:FAM61A(gene name synonym)|uniprotkb:Protein SCD6 homolog(gene name synonym)|uniprotkb:Protein FAM61A(gene name synonym)|uniprotkb:Putative alpha-synuclein-binding protein(gene name synonym)|uniprotkb:LSM14A(gene name)|psi-mi:LSM14A(display_short)|uniprotkb:RAP55(gene name synonym)|uniprotkb:RAP55A(gene name synonym)|uniprotkb:RNA-associated protein 55A(gene name synonym)	psi-mi:a0a6l8pg64_bacan(display_long)|uniprotkb:GBAA_3631(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830321|imex:IM-13779-3405	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001107565.1|refseq:NP_056393.2|ensembl:ENSG00000257103.9(gene)|ensembl:ENSG00000262860.5(gene)|ensembl:ENST00000433627.9(transcript)|ensembl:ENST00000570462.5(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0033962""(P-body assembly)|go:""GO:0034063""(stress granule assembly)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0039529""(RIG-I signaling pathway)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|interpro:IPR047575|mint:Q8ND56|rcsb pdb:6F9W|panther:PTHR13586(orthology-group)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR001041(Ferredoxin)|interpro:IPR006478(Formate dehydrogenase, alpha subunit)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR019574|interpro:IPR050123|go:""GO:0003954""(NADH dehydrogenase activity)|go:""GO:0008863""(""formate dehydrogenase (NAD+) activity"")|go:""GO:0015942""(formate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_000794675.1|interpro:IPR036010|interpro:IPR041924"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YW/zx4XyhcZZr3WCZIr1OVpyakA9606	rogid:QIgvJ3jy6mN9lKyYhw7Vk06JkC01392	intact-crc:2544B47CEBFB66F4|rigid:TRZHPDcEllwwNhtjtHL0Y4YvaNc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15116	uniprotkb:D1MPY3	intact:EBI-347619|ensembl:ENSP00000310596.4|uniprotkb:B2R5E6	intact:EBI-63974350	psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym)	psi-mi:d1mpy3_bacan(display_long)|uniprotkb:GBAA_4848(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830307|imex:IM-13779-3407	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000175324.10(gene)|ensembl:ENST00000311351.9(transcript)|go:""GO:0000290""(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:""GO:0000375""(RNA splicing, via transesterification reactions)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0019827""(stem cell population maintenance)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:1990726""(Lsm1-7-Pat1 complex)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|interpro:IPR047575|mint:O15116|reactome:R-HSA-430039|refseq:NP_055277.1|dip:DIP-31130N|panther:PTHR15588(orthology-group)|ensembl:ENSP00000310596.4"	"go:""GO:0004471""(""malate dehydrogenase (decarboxylating) (NAD+) activity"")|go:""GO:0046872""(metal ion binding)|go:""GO:0051287""(NAD binding)|go:""GO:0008948""(oxaloacetate decarboxylase activity)|interpro:IPR046346|interpro:IPR051674|interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR037062|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR045213|interpro:IPR001891(Malic oxidoreductase)|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/21	rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606	rogid:EErQsU3Tj+3HaUDRtvpfD+OD6j01392	intact-crc:DD5874B9504E8F5D|rigid:CoSTk1oEieTRDtnZWVpKEMWr08k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94898	uniprotkb:A0A6L7H746	intact:EBI-2830372|uniprotkb:Q9NSN2|ensembl:ENSP00000355396.4	intact:EBI-2814087|uniprotkb:Q6KRL9|uniprotkb:Q6HXJ3|uniprotkb:E9R7D3|uniprotkb:E9R7D4|uniprotkb:A0A2P0HFK2|uniprotkb:Q81PC9	psi-mi:lrig2_human(display_long)|uniprotkb:LRIG2(gene name)|psi-mi:LRIG2(display_short)|uniprotkb:KIAA0806(gene name synonym)|uniprotkb:LIG2(gene name synonym)	psi-mi:a0a6l7h746_bacan(display_long)|uniprotkb:GBAA_2881(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830378|imex:IM-13779-3412	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2704""|ensembl:ENSG00000198799.12(gene)|ensembl:ENST00000361127.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006509""(membrane protein ectodomain proteolysis)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0010640""(regulation of platelet-derived growth factor receptor signaling pathway)|go:""GO:0030426""(growth cone)|go:""GO:0031012""(extracellular matrix)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0048681""(negative regulation of axon regeneration)|go:""GO:0051045""(negative regulation of membrane protein ectodomain proteolysis)|go:""GO:0060384""(innervation)|go:""GO:0097708""(intracellular vesicle)|go:""GO:2000010""(positive regulation of protein localization to cell surface)|go:""GO:2001222""(regulation of neuron migration)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032675|interpro:IPR036179|interpro:IPR050467|refseq:NP_001299615.1|refseq:NP_055628.1|panther:PTHR24373(orthology-group)"	"interpro:IPR000914(Bacterial extracellular solute-binding protein, family 5)|interpro:IPR025370|go:""GO:0003677""(DNA binding)|go:""GO:0015833""(peptide transport)|go:""GO:1904680""(peptide transmembrane transporter activity)|interpro:IPR039424|refseq:WP_000470174.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Onv6Wv8jh1k2NSzmTGJU1QD3g6Q9606	rogid:wujrf6fma4hOQ/mHRPw+P7fVqwE1392	intact-crc:FF6AB6E85BD06D73|rigid:mOBbHUoJnEwlrnbeCBZxe5mZ/jM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HKT5	uniprotkb:Q7Z4F1	intact:EBI-2830360|uniprotkb:Q6HZ84|uniprotkb:Q6KT77|uniprotkb:E9R634|uniprotkb:E9R635|uniprotkb:A0A2P0HDM4|uniprotkb:Q81R13	intact:EBI-2830349|uniprotkb:Q8NCZ4|uniprotkb:Q9HC42|uniprotkb:O95882|uniprotkb:Q14CK7|uniprotkb:Q9UG33|uniprotkb:Q86T02|uniprotkb:A8K4R5|uniprotkb:D3DS31|ensembl:ENSP00000352601.4	psi-mi:a0a6l7hkt5_bacan(display_long)|uniprotkb:GBAA_2246(locus name)	psi-mi:lrp10_human(display_long)|uniprotkb:LRP10(gene name)|psi-mi:LRP10(display_short)|uniprotkb:MSTP087(orf name)|uniprotkb:SP220(orf name)|uniprotkb:UNQ389/PRO724(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830365|imex:IM-13779-3410	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003797(DegV)|refseq:WP_003169578.1|go:""GO:0008289""(lipid binding)|interpro:IPR043168|interpro:IPR050270"	"refseq:NP_054764.2|refseq:NP_001316155.1|ensembl:ENSG00000197324.9(gene)|ensembl:ENST00000359591.9(transcript)|go:""GO:0005041""(low-density lipoprotein particle receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006869""(lipid transport)|go:""GO:0006897""(endocytosis)|go:""GO:0016020""(membrane)|go:""GO:0048839""(inner ear development)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|interpro:IPR050685|mint:Q7Z4F1|reactome:R-HSA-975634|panther:PTHR24270(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H8TGMy9xiNOxV8gWP7WTK7KRoBM1392	rogid:wXlXHoFbJyH8IwNBjkXzb81X3pA9606	intact-crc:CD9214ED94FA42F4|rigid:aaLSqlQn4vNi7cQfJ/QLj4p3+LM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VT8	uniprotkb:O75096	intact:EBI-2811891|uniprotkb:Q6I4U2	intact:EBI-310873|uniprotkb:B2RN39|uniprotkb:Q4AC85|uniprotkb:Q5KTZ5|ensembl:ENSP00000367888.1	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	psi-mi:lrp4_human(display_long)|uniprotkb:LRP4(gene name)|psi-mi:LRP4(display_short)|uniprotkb:KIAA0816(gene name synonym)|uniprotkb:MEGF7(gene name synonym)|uniprotkb:Multiple epidermal growth factor-like domains 7(gene name synonym)|uniprotkb:LRP10(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830342|imex:IM-13779-3409	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"efo:""Orphanet:3152""|efo:""Orphanet:3258""|efo:""Orphanet:98913""|ensembl:ENSG00000134569.10(gene)|ensembl:ENST00000378623.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001942""(hair follicle development)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0007167""(enzyme-linked receptor protein signaling pathway)|go:""GO:0009953""(dorsal/ventral pattern formation)|go:""GO:0009954""(proximal/distal pattern formation)|go:""GO:0009986""(cell surface)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0030425""(dendrite)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0034185""(apolipoprotein binding)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0048699""(generation of neurons)|go:""GO:0048813""(dendrite morphogenesis)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050771""(negative regulation of axonogenesis)|go:""GO:0050808""(synapse organization)|go:""GO:0051124""(synaptic assembly at neuromuscular junction)|go:""GO:0060173""(limb development)|go:""GO:0071340""(skeletal muscle acetylcholine-gated channel clustering)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097104""(postsynaptic membrane assembly)|go:""GO:0097105""(presynaptic membrane assembly)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:0150094""(amyloid-beta clearance by cellular catabolic process)|go:""GO:1901631""(positive regulation of presynaptic membrane organization)|go:""GO:1904395""(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|interpro:IPR051221|mint:O75096|rcsb pdb:8S9P|reactome:R-HSA-3000178|refseq:NP_002325.2|panther:PTHR24270(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	rogid:IbVlpu46vNtRqtZvYsySZ6go3kE9606	intact-crc:0489DCEE61C46FBD|rigid:nTXx3k2E9KtK/EbIvmlBzBYgm0A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7REH3	uniprotkb:O75197	intact:EBI-2811064|uniprotkb:Q6KPV8|uniprotkb:E9R093|uniprotkb:Q81YE8	intact:EBI-2466421|uniprotkb:Q96TD6|uniprotkb:Q9UP66|uniprotkb:Q9UES7|ensembl:ENSP00000294304.6	psi-mi:a0a0f7reh3_bacan(display_long)|uniprotkb:GBAA_3601(locus name)	psi-mi:lrp5_human(display_long)|uniprotkb:LRP5(gene name)|psi-mi:LRP5(display_short)|uniprotkb:LRP7(gene name synonym)|uniprotkb:LR3(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein 7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830335|imex:IM-13779-3411	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001116379.1|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR047589	"dip:DIP-47265N|ensembl:ENSG00000162337.12(gene)|ensembl:ENST00000294304.12(transcript)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0002053""(positive regulation of mesenchymal cell proliferation)|go:""GO:0002076""(osteoblast development)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006865""(amino acid transport)|go:""GO:0006897""(endocytosis)|go:""GO:0007399""(nervous system development)|go:""GO:0008078""(mesodermal cell migration)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009952""(anterior/posterior pattern specification)|go:""GO:0010467""(gene expression)|go:""GO:0015026""(coreceptor activity)|go:""GO:0017147""(Wnt-protein binding)|go:""GO:0033687""(osteoblast proliferation)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0035426""(extracellular matrix-cell signaling)|go:""GO:0042074""(cell migration involved in gastrulation)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0042813""(Wnt receptor activity)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0045840""(positive regulation of mitotic nuclear division)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046849""(bone remodeling)|go:""GO:0048539""(bone marrow development)|go:""GO:0060033""(anatomical structure regression)|go:""GO:0060042""(retina morphogenesis in camera-type eye)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0060444""(branching involved in mammary gland duct morphogenesis)|go:""GO:0060612""(adipose tissue development)|go:""GO:0060764""(cell-cell signaling involved in mammary gland development)|go:""GO:0060856""(establishment of blood-brain barrier)|go:""GO:0061178""(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:""GO:0061304""(retinal blood vessel morphogenesis)|go:""GO:0071901""(negative regulation of protein serine/threonine kinase activity)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0110135""(Norrin signaling pathway)|go:""GO:1902262""(apoptotic process involved in blood vessel morphogenesis)|go:""GO:1990851""(Wnt-Frizzled-LRP5/6 complex)|go:""GO:1990909""(Wnt signalosome)|go:""GO:1990963""(establishment of blood-retinal barrier)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR017049(Low density lipoprotein receptor-related protein, 5/6)|interpro:IPR023415|interpro:IPR036055|interpro:IPR050778|mint:O75197|reactome:R-HSA-201681|reactome:R-HSA-3772470|reactome:R-HSA-4641262|reactome:R-HSA-4641263|reactome:R-HSA-5339717|reactome:R-HSA-5340588|refseq:NP_001278831.1|refseq:NP_002326.2|efo:""Orphanet:178377""|efo:""Orphanet:2783""|efo:""Orphanet:2788""|efo:""Orphanet:2790""|efo:""Orphanet:2924""|efo:""Orphanet:3416""|efo:""Orphanet:498481""|efo:""Orphanet:891""|efo:""Orphanet:90050""|panther:PTHR46513(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:kRV2TrznOHMKW2jOg5FKoFx9L+41392	rogid:5Or5NJwtSvZrk2kM2bBAQQOCW749606	intact-crc:43A534ED7569F247|rigid:M86+YzivfSTkds/ZVabVZ9pEqf0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VE0	uniprotkb:Q03252	intact:EBI-2830418|uniprotkb:Q6KY45|uniprotkb:Q6I4E2	intact:EBI-2830427|uniprotkb:O75292|uniprotkb:Q14734|uniprotkb:Q96DF6|intact:EBI-11044751|ensembl:ENSP00000327054.3|intact:EBI-20728818	psi-mi:guaa_bacan(display_long)|uniprotkb:guaA(gene name)|psi-mi:guaA(display_short)|uniprotkb:GMP synthetase(gene name synonym)|uniprotkb:Glutamine amidotransferase(gene name synonym)|uniprotkb:BA_0268(locus name)|uniprotkb:GBAA_0268(locus name)|uniprotkb:BAS0254(locus name)	psi-mi:lmnb2_human(display_long)|uniprotkb:LMNB2(gene name)|psi-mi:LMNB2(display_short)|uniprotkb:LMN2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830424|imex:IM-13779-3415	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029062|interpro:IPR017926|interpro:IPR001674(GMP synthase, C-terminal)|interpro:IPR004739(GMP synthase, N-terminal)|interpro:IPR022955|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR025777|interpro:IPR022310|go:""GO:0003921""(GMP synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|refseq:WP_000743900.1|refseq:NP_842821.1"	"efo:""Orphanet:457265""|efo:""Orphanet:79087""|ensembl:ENSG00000176619.13(gene)|ensembl:ENST00000325327.4(transcript)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005882""(intermediate filament)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0090435""(protein localization to nuclear envelope)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:Q03252|rcsb pdb:2LLL|refseq:NP_116126.3|dip:DIP-57724N|panther:PTHR45721(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:oRBxha13TYp5xmWYgyEQ4QrNJfo1392	rogid:Jt7rEo5Br8HidU+VAc0L6rtBU889606	intact-crc:02E04450EF517832|rigid:vpueF1WKa0SqsoLkIwxGlsX80Ik	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AGX8	uniprotkb:O60711	intact:EBI-2820004|uniprotkb:Q6KP00|uniprotkb:Q6HUR8|uniprotkb:E9QZS8|uniprotkb:E9QZS9|uniprotkb:Q81WL8|uniprotkb:A0A0J1I0J1	intact:EBI-744222|uniprotkb:B4DV71|uniprotkb:Q53FW6|uniprotkb:Q6FI07|uniprotkb:B2R8B4|intact:EBI-5773608|ensembl:ENSP00000378512.2	psi-mi:a0a6h3agx8_bacan(display_long)|uniprotkb:polC(gene name)|psi-mi:polC(display_short)|uniprotkb:GBAA_3955(locus name)	psi-mi:lpxn_human(display_long)|uniprotkb:LPXN(gene name)|psi-mi:LPXN(display_short)|uniprotkb:LDLP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830392|imex:IM-13779-3413	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044923|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR006054(DNA polymerase III, epsilon subunit)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR006308(DNA polymerase III, alpha subunit, Gram-positive type)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR024754|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028112|interpro:IPR029460|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0008408""(3'-5' exonuclease activity)|refseq:WP_000059985.1|interpro:IPR036397|interpro:IPR040982|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)"	"refseq:NP_001137467.1|refseq:NP_004802.1|refseq:NP_001294880.1|ensembl:ENSG00000110031.13(gene)|ensembl:ENST00000395074.7(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0033628""(regulation of cell adhesion mediated by integrin)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042995""(cell projection)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:O60711|rcsb pdb:1X3H|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|panther:PTHR24216(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:05wEb6yT9+SpXL8rr+L5dFHECug1392	rogid:Olw/LB7LvTdx2OVIuLreg5miQp49606	intact-crc:5B537DED3421FDF7|rigid:pkgSqOmNt/8u2O/FQCR2wHIKYNk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92539	uniprotkb:Q81M06	intact:EBI-2830409|uniprotkb:A7MD25|uniprotkb:D3DUH3|ensembl:ENSP00000261596.4|ensembl:ENSP00000504857.1|ensembl:ENSP00000513062.1	intact:EBI-2818574|uniprotkb:Q6KMQ1|uniprotkb:Q6HTF8	psi-mi:lpin2_human(display_long)|uniprotkb:LPIN2(gene name)|psi-mi:LPIN2(display_short)|uniprotkb:KIAA0249(gene name synonym)|uniprotkb:Lipin-2(gene name synonym)	psi-mi:gcst_bacan(display_long)|uniprotkb:gcvT(gene name)|psi-mi:gcvT(display_short)|uniprotkb:Glycine cleavage system T protein(gene name synonym)|uniprotkb:BA_4449(locus name)|uniprotkb:GBAA_4449(locus name)|uniprotkb:BAS4131(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830406|imex:IM-13779-3414	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:77297""|ensembl:ENSG00000101577.11(gene)|ensembl:ENST00000261596.9(transcript)|ensembl:ENST00000677752.1(transcript)|ensembl:ENST00000697040.1(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0008195""(phosphatidate phosphatase activity)|go:""GO:0009062""(fatty acid catabolic process)|go:""GO:0019432""(triglyceride biosynthetic process)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR007651(Lipin, N-terminal conserved region)|interpro:IPR013209(LNS2, Lipin/Ned1/Smp2)|interpro:IPR026058|interpro:IPR031315|interpro:IPR031703|interpro:IPR036412|reactome:R-HSA-1483191|reactome:R-HSA-1483213|reactome:R-HSA-4419969|reactome:R-HSA-75109|refseq:NP_055461.1|refseq:XP_005258235.1|refseq:XP_005258236.1|refseq:XP_016881587.1|refseq:XP_016881588.1|panther:PTHR12181(orthology-group)"	"refseq:WP_000631769.1|interpro:IPR013977(Glycine cleavage T-protein, C-terminal barrel)|interpro:IPR006222(Glycine cleavage T-protein, N-terminal)|interpro:IPR006223(Glycine cleavage system T protein)|interpro:IPR022903|interpro:IPR029043|go:""GO:0004047""(aminomethyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0008483""(transaminase activity)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|interpro:IPR027266|interpro:IPR028896|refseq:NP_846677.1|refseq:YP_030380.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IpcadfNULLH9V2XG5OMCyqwxSro9606	rogid:7XsM5cRzXzdzp/UaKC2rcq3w3Xs1392	intact-crc:9B654EBFB8359D60|rigid:bQUM5smIRPGu/Wr4aMubtJgkFYA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HE73	uniprotkb:Q96CN5	intact:EBI-2813877|uniprotkb:Q6HRP6|uniprotkb:Q6KL13|uniprotkb:E9QT89|uniprotkb:E9QT90|uniprotkb:Q81K96|uniprotkb:A0A0J1HS73|uniprotkb:A0A348ABD5	intact:EBI-2805176|ensembl:ENSP00000306760.3	psi-mi:a0a6l7he73_bacan(display_long)|uniprotkb:menB(gene name)|psi-mi:menB(display_short)|uniprotkb:GBAA_5109(locus name)	psi-mi:lrc45_human(display_long)|uniprotkb:LRRC45(gene name)|psi-mi:LRRC45(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830385|imex:IM-13779-3417	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|interpro:IPR010198(Naphthoate synthase)|interpro:IPR029045|go:""GO:0005829""(cytosol)|go:""GO:0008935""(1,4-dihydroxy-2-naphthoyl-CoA synthase activity)|go:""GO:0009234""(menaquinone biosynthetic process)|refseq:WP_000963873.1"	"refseq:NP_659436.1|ensembl:ENSG00000169683.8(gene)|ensembl:ENST00000306688.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR052116|mint:Q96CN5|dip:DIP-29482N|panther:PTHR23170(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	crc64:27F5D210721459FB	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:QcWu71AxxEE8Dr8cb9DlLXh7oEY1392	rogid:cuIAlpH4zLJ1La+TtOc2x4c2dMI9606	intact-crc:227501FC8A429A25|rigid:Ykyan/LtfQgW9gJfaOOVgvpgQlE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P42704	uniprotkb:Q81ME0	intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665.7	intact:EBI-2813646|uniprotkb:Q6KN28|uniprotkb:Q6HTU1	psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym)	psi-mi:deob_bacan(display_long)|uniprotkb:deoB(gene name)|psi-mi:deoB(display_short)|uniprotkb:Phosphodeoxyribomutase(gene name synonym)|uniprotkb:BA_4309(locus name)|uniprotkb:GBAA_4309(locus name)|uniprotkb:BAS3997(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830399|imex:IM-13779-3416	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-27543N|ensembl:ENSG00000138095.20(gene)|ensembl:ENST00000260665.12(transcript)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0000957""(mitochondrial RNA catabolic process)|go:""GO:0000961""(negative regulation of mitochondrial RNA catabolic process)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005874""(microtubule)|go:""GO:0006914""(autophagy)|go:""GO:0008017""(microtubule binding)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0051028""(mRNA transport)|go:""GO:0070129""(regulation of mitochondrial translation)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|rcsb pdb:8ANY|reactome:R-HSA-9836573|refseq:NP_573566.2|efo:""Orphanet:70472""|panther:PTHR46669(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR010045(Phosphopentomutase)|interpro:IPR006124(Metalloenzyme)|interpro:IPR024052|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006015""(5-phosphoribose 1-diphosphate biosynthetic process)|go:""GO:0006018""(2-deoxyribose 1-phosphate catabolic process)|go:""GO:0008973""(phosphopentomutase activity)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0043094""(metabolic compound salvage)|refseq:WP_001046068.1|refseq:NP_846542.1|refseq:YP_030247.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606	rogid:4rSH7u8wKFseFpqFRuqEYAYDNTo1392	intact-crc:E08BBA8F237BE6CD|rigid:dJgEHZ20RIQC4x9V3HDNKFEoASk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20700	uniprotkb:A0A6L8P0F0	intact:EBI-968218|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6|ensembl:ENSP00000261366.5	intact:EBI-2823931|uniprotkb:Q6HXU1|uniprotkb:Q6KRW2|uniprotkb:E9QYS3|uniprotkb:E9QYS4|uniprotkb:A0A2P0HF63|uniprotkb:Q81PM6	psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym)	psi-mi:a0a6l8p0f0_bacan(display_long)|uniprotkb:acoA(gene name)|psi-mi:acoA(display_short)|uniprotkb:GBAA_2776(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830445|imex:IM-13779-3420	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2514""|efo:""Orphanet:99027""|dip:DIP-34897N|ensembl:ENSG00000113368.12(gene)|ensembl:ENST00000261366.10(transcript)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043274""(phospholipase binding)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|rcsb pdb:3UMN|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:5BNW|rcsb pdb:5VVX|rcsb pdb:7DTG|reactome:R-HSA-1221632|reactome:R-HSA-2559584|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|panther:PTHR45721(orthology-group)"	"interpro:IPR029061|interpro:IPR001017(Dehydrogenase, E1 component)|go:""GO:0004739""(""pyruvate dehydrogenase (acetyl-transferring) activity"")|go:""GO:0006086""(pyruvate decarboxylation to acetyl-CoA)|refseq:WP_000921260.1|interpro:IPR050642"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606	rogid:KS8Wi18rQLkKs9KoOh4je3EkFZc1392	intact-crc:41A9ACFDAC46D82F|rigid:xpCjL1TNWVSMdceyBlZLDJc1WJ0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P438	uniprotkb:P02545	intact:EBI-2813865|uniprotkb:Q6I2Q7|uniprotkb:Q6KWI7|uniprotkb:E9QYZ9|uniprotkb:E9QZ00|uniprotkb:A0A2P0HAN0|uniprotkb:Q81UH9	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292.6|ensembl:ENSP00000357283.4|ensembl:ENSP00000502256.1|ensembl:ENSP00000506771.1	psi-mi:a0a6l8p438_bacan(display_long)|uniprotkb:GBAA_0893(locus name)	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830452|imex:IM-13779-3421	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_000256693.1|interpro:IPR049504"	"efo:""Orphanet:154""|efo:""Orphanet:157973""|efo:""Orphanet:1662""|efo:""Orphanet:168796""|efo:""Orphanet:2229""|efo:""Orphanet:2348""|efo:""Orphanet:280365""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:300751""|efo:""Orphanet:363618""|efo:""Orphanet:54260""|efo:""Orphanet:740""|efo:""Orphanet:79084""|efo:""Orphanet:79474""|efo:""Orphanet:90153""|efo:""Orphanet:98853""|efo:""Orphanet:98855""|efo:""Orphanet:98856""|efo:""Orphanet:675396""|ensembl:ENSG00000160789.25(gene)|ensembl:ENST00000361308.9(transcript)|ensembl:ENST00000368300.9(transcript)|ensembl:ENST00000675939.1(transcript)|ensembl:ENST00000683032.1(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005882""(intermediate filament)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0007517""(muscle organ development)|go:""GO:0008104""(protein localization)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030951""(establishment or maintenance of microtubule cytoskeleton polarity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072201""(negative regulation of mesenchymal cell proliferation)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1900180""(regulation of protein localization to nucleus)|go:""GO:1903243""(negative regulation of cardiac muscle hypertrophy in response to stress)|go:""GO:1990683""(DNA double-strand break attachment to nuclear envelope)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|rcsb pdb:7CRG|rcsb pdb:7D9N|rcsb pdb:7WZZ|rcsb pdb:7X1B|rcsb pdb:7X5D|rcsb pdb:7YVD|rcsb pdb:7Z21|rcsb pdb:8I33|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|dip:DIP-32948N|dip:DIP-58162N|panther:PTHR45721(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kBl7RIaAvsi/FXyeTeK2QDAM4881392	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	intact-crc:63B38530C27A8F15|rigid:l2SoIt60wBpfixR8+Aou7Nd/OZI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P02545	uniprotkb:A0A6L8PR63	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292.6|ensembl:ENSP00000357283.4|ensembl:ENSP00000502256.1|ensembl:ENSP00000506771.1	intact:EBI-2830459|uniprotkb:Q6I3U1|uniprotkb:Q6KXK4|uniprotkb:E9R8F1|uniprotkb:E9R8F2|uniprotkb:Q81YZ4|uniprotkb:A0A0F7RJK8	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	psi-mi:a0a6l8pr63_bacan(display_long)|uniprotkb:GBAA_0483(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830464|imex:IM-13779-3419	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:154""|efo:""Orphanet:157973""|efo:""Orphanet:1662""|efo:""Orphanet:168796""|efo:""Orphanet:2229""|efo:""Orphanet:2348""|efo:""Orphanet:280365""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:300751""|efo:""Orphanet:363618""|efo:""Orphanet:54260""|efo:""Orphanet:740""|efo:""Orphanet:79084""|efo:""Orphanet:79474""|efo:""Orphanet:90153""|efo:""Orphanet:98853""|efo:""Orphanet:98855""|efo:""Orphanet:98856""|efo:""Orphanet:675396""|ensembl:ENSG00000160789.25(gene)|ensembl:ENST00000361308.9(transcript)|ensembl:ENST00000368300.9(transcript)|ensembl:ENST00000675939.1(transcript)|ensembl:ENST00000683032.1(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005882""(intermediate filament)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0007517""(muscle organ development)|go:""GO:0008104""(protein localization)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030951""(establishment or maintenance of microtubule cytoskeleton polarity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072201""(negative regulation of mesenchymal cell proliferation)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1900180""(regulation of protein localization to nucleus)|go:""GO:1903243""(negative regulation of cardiac muscle hypertrophy in response to stress)|go:""GO:1990683""(DNA double-strand break attachment to nuclear envelope)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|rcsb pdb:7CRG|rcsb pdb:7D9N|rcsb pdb:7WZZ|rcsb pdb:7X1B|rcsb pdb:7X5D|rcsb pdb:7YVD|rcsb pdb:7Z21|rcsb pdb:8I33|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|dip:DIP-32948N|dip:DIP-58162N|panther:PTHR45721(orthology-group)"	"interpro:IPR019715|refseq:WP_000818882.1|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	rogid:KPpEeXuAzhHhxnOUwjSwfpposCg1392	intact-crc:C23104B6C72DAC45|rigid:DcmS+c26EgD3pvGGpQy8z6CH5zk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20700	uniprotkb:A0A0F7RE19	intact:EBI-968218|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6|ensembl:ENSP00000261366.5	intact:EBI-2809783|uniprotkb:Q6KPM6|uniprotkb:Q6HVF7|uniprotkb:E9QS28|uniprotkb:E9QS29|uniprotkb:Q81Y62	psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym)	psi-mi:a0a0f7re19_bacan(display_long)|uniprotkb:GBAA_3695(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830438|imex:IM-13779-3418	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2514""|efo:""Orphanet:99027""|dip:DIP-34897N|ensembl:ENSG00000113368.12(gene)|ensembl:ENST00000261366.10(transcript)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043274""(phospholipase binding)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|rcsb pdb:3UMN|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:5BNW|rcsb pdb:5VVX|rcsb pdb:7DTG|reactome:R-HSA-1221632|reactome:R-HSA-2559584|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|panther:PTHR45721(orthology-group)"	"interpro:IPR001119(S-layer homology region)|interpro:IPR051465|go:""GO:0030115""(S-layer)|interpro:IPR032247"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606	rogid:RZeq/OQN8n8nnEe280+/uO/FFX01392	intact-crc:AAAFAADC677A4C0F|rigid:NFohYJvlOkJ+FmhODpUTTV+rkWA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HF22	uniprotkb:P49257	intact:EBI-2830497|uniprotkb:Q6KNP3|uniprotkb:Q6HUF6|uniprotkb:E9QXG9|uniprotkb:E9QXH0|uniprotkb:Q81WB2|uniprotkb:A0A0F7R7R1	intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047.4|intact:EBI-21355115	psi-mi:a0a6l7hf22_bacan(display_long)|uniprotkb:GBAA_4070(locus name)	psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830502|imex:IM-13779-3423	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000394503.1|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|go:""GO:0003677""(DNA binding)"	"ensembl:ENSG00000074695.6(gene)|ensembl:ENST00000251047.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005537""(D-mannose binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006457""(protein folding)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007596""(blood coagulation)|go:""GO:0010638""(positive regulation of organelle organization)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0030017""(sarcomere)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0046872""(metal ion binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903215""(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR051136|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|rcsb pdb:8JP4|rcsb pdb:8JP5|rcsb pdb:8JP6|rcsb pdb:8JP7|rcsb pdb:8JP8|rcsb pdb:8JP9|rcsb pdb:8JPG|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-948021|refseq:NP_005561.1|efo:""Orphanet:35909""|dip:DIP-42188N|panther:PTHR12223(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:ejKXnPjlmjcKIDWK9Oxsz1phUXM1392	rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606	intact-crc:D336649BA7E0CAAD|rigid:uRpQn2SsxK4CEZnleJTMhOlLySE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P02545	uniprotkb:Q81X15	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292.6|ensembl:ENSP00000357283.4|ensembl:ENSP00000502256.1|ensembl:ENSP00000506771.1	intact:EBI-2830485|uniprotkb:Q6KXI7|uniprotkb:E9QR26	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	psi-mi:q81x15_bacan(display_long)|uniprotkb:ugd(gene name)|psi-mi:ugd(display_short)|uniprotkb:GBAA_5434(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830490|imex:IM-13779-3425	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:154""|efo:""Orphanet:157973""|efo:""Orphanet:1662""|efo:""Orphanet:168796""|efo:""Orphanet:2229""|efo:""Orphanet:2348""|efo:""Orphanet:280365""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:300751""|efo:""Orphanet:363618""|efo:""Orphanet:54260""|efo:""Orphanet:740""|efo:""Orphanet:79084""|efo:""Orphanet:79474""|efo:""Orphanet:90153""|efo:""Orphanet:98853""|efo:""Orphanet:98855""|efo:""Orphanet:98856""|efo:""Orphanet:675396""|ensembl:ENSG00000160789.25(gene)|ensembl:ENST00000361308.9(transcript)|ensembl:ENST00000368300.9(transcript)|ensembl:ENST00000675939.1(transcript)|ensembl:ENST00000683032.1(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005882""(intermediate filament)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0007517""(muscle organ development)|go:""GO:0008104""(protein localization)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030951""(establishment or maintenance of microtubule cytoskeleton polarity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072201""(negative regulation of mesenchymal cell proliferation)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1900180""(regulation of protein localization to nucleus)|go:""GO:1903243""(negative regulation of cardiac muscle hypertrophy in response to stress)|go:""GO:1990683""(DNA double-strand break attachment to nuclear envelope)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|rcsb pdb:7CRG|rcsb pdb:7D9N|rcsb pdb:7WZZ|rcsb pdb:7X1B|rcsb pdb:7X5D|rcsb pdb:7YVD|rcsb pdb:7Z21|rcsb pdb:8I33|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|dip:DIP-32948N|dip:DIP-58162N|panther:PTHR45721(orthology-group)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR028357|go:""GO:0000271""(polysaccharide biosynthetic process)|go:""GO:0003979""(UDP-glucose 6-dehydrogenase activity)|go:""GO:0006065""(UDP-glucuronate biosynthetic process)|go:""GO:0051287""(NAD binding)|interpro:IPR036220|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	rogid:tKDpd3M2GL+U1UAmHqMhCq5YoS01392	intact-crc:FCF47BC3D5207878|rigid:rJCTQlDlEmwV6z5UeOWXbIAjVS4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P912	uniprotkb:P02545	intact:EBI-2813087|uniprotkb:Q6HRB8|uniprotkb:Q6KKN4|uniprotkb:E9QXK2|uniprotkb:E9QXK3|uniprotkb:Q81XI5|uniprotkb:A0A0J1HL81|uniprotkb:A0A1T3VA01	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292.6|ensembl:ENSP00000357283.4|ensembl:ENSP00000502256.1|ensembl:ENSP00000506771.1	psi-mi:a0a6l8p912_bacan(display_long)|uniprotkb:GBAA_5252(locus name)	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830478|imex:IM-13779-3424	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000831474.1|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR018044|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)"	"efo:""Orphanet:154""|efo:""Orphanet:157973""|efo:""Orphanet:1662""|efo:""Orphanet:168796""|efo:""Orphanet:2229""|efo:""Orphanet:2348""|efo:""Orphanet:280365""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:300751""|efo:""Orphanet:363618""|efo:""Orphanet:54260""|efo:""Orphanet:740""|efo:""Orphanet:79084""|efo:""Orphanet:79474""|efo:""Orphanet:90153""|efo:""Orphanet:98853""|efo:""Orphanet:98855""|efo:""Orphanet:98856""|efo:""Orphanet:675396""|ensembl:ENSG00000160789.25(gene)|ensembl:ENST00000361308.9(transcript)|ensembl:ENST00000368300.9(transcript)|ensembl:ENST00000675939.1(transcript)|ensembl:ENST00000683032.1(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005882""(intermediate filament)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0007517""(muscle organ development)|go:""GO:0008104""(protein localization)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030951""(establishment or maintenance of microtubule cytoskeleton polarity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072201""(negative regulation of mesenchymal cell proliferation)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1900180""(regulation of protein localization to nucleus)|go:""GO:1903243""(negative regulation of cardiac muscle hypertrophy in response to stress)|go:""GO:1990683""(DNA double-strand break attachment to nuclear envelope)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|rcsb pdb:7CRG|rcsb pdb:7D9N|rcsb pdb:7WZZ|rcsb pdb:7X1B|rcsb pdb:7X5D|rcsb pdb:7YVD|rcsb pdb:7Z21|rcsb pdb:8I33|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|dip:DIP-32948N|dip:DIP-58162N|panther:PTHR45721(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5PfgpApOBC2X6AToaugb6KcFzKo1392	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	intact-crc:C3104E4F2C57B0CE|rigid:fDEMjGw10Z1R+rLpk3ezkCo8xSw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:P02545	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292.6|ensembl:ENSP00000357283.4|ensembl:ENSP00000502256.1|ensembl:ENSP00000506771.1	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830471|imex:IM-13779-3422	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"efo:""Orphanet:154""|efo:""Orphanet:157973""|efo:""Orphanet:1662""|efo:""Orphanet:168796""|efo:""Orphanet:2229""|efo:""Orphanet:2348""|efo:""Orphanet:280365""|efo:""Orphanet:293888""|efo:""Orphanet:293899""|efo:""Orphanet:293910""|efo:""Orphanet:300751""|efo:""Orphanet:363618""|efo:""Orphanet:54260""|efo:""Orphanet:740""|efo:""Orphanet:79084""|efo:""Orphanet:79474""|efo:""Orphanet:90153""|efo:""Orphanet:98853""|efo:""Orphanet:98855""|efo:""Orphanet:98856""|efo:""Orphanet:675396""|ensembl:ENSG00000160789.25(gene)|ensembl:ENST00000361308.9(transcript)|ensembl:ENST00000368300.9(transcript)|ensembl:ENST00000675939.1(transcript)|ensembl:ENST00000683032.1(transcript)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005638""(lamin filament)|go:""GO:0005652""(nuclear lamina)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005882""(intermediate filament)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006998""(nuclear envelope organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0007517""(muscle organ development)|go:""GO:0008104""(protein localization)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030951""(establishment or maintenance of microtubule cytoskeleton polarity)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042802""(identical protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051664""(nuclear pore localization)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0072201""(negative regulation of mesenchymal cell proliferation)|go:""GO:0090201""(negative regulation of release of cytochrome c from mitochondria)|go:""GO:0090398""(cellular senescence)|go:""GO:0090435""(protein localization to nuclear envelope)|go:""GO:0160123""(structural constituent of nuclear lamina)|go:""GO:1900180""(regulation of protein localization to nucleus)|go:""GO:1903243""(negative regulation of cardiac muscle hypertrophy in response to stress)|go:""GO:1990683""(DNA double-strand break attachment to nuclear envelope)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|rcsb pdb:7CRG|rcsb pdb:7D9N|rcsb pdb:7WZZ|rcsb pdb:7X1B|rcsb pdb:7X5D|rcsb pdb:7YVD|rcsb pdb:7Z21|rcsb pdb:8I33|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|dip:DIP-32948N|dip:DIP-58162N|panther:PTHR45721(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	intact-crc:F9B1F8C3D6FE94D9|rigid:GEcJweadi1z1XcXE88MyJ1P7M38	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y5X9	uniprotkb:A0A6H3AF39	intact:EBI-372509|uniprotkb:Q6P9C8|uniprotkb:Q6UW82|ensembl:ENSP00000261292.4|uniprotkb:B0LPG6	intact:EBI-2817647|uniprotkb:Q6I1K9|uniprotkb:Q6KVF9|uniprotkb:E9R1P4|uniprotkb:E9R1P5|uniprotkb:Q81TD3|uniprotkb:A0A0F7RKP7	psi-mi:lipg_human(display_long)|uniprotkb:Phospholipase A1(gene name synonym)|uniprotkb:UNQ387/PRO719(orf name)|uniprotkb:Endothelial cell-derived lipase(gene name synonym)|uniprotkb:LIPG(gene name)|psi-mi:LIPG(display_short)	psi-mi:a0a6h3af39_bacan(display_long)|uniprotkb:GBAA_1351(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830559|imex:IM-13779-3430	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000101670.12(gene)|ensembl:ENST00000261292.9(transcript)|go:""GO:0004465""(lipoprotein lipase activity)|go:""GO:0004620""(phospholipase activity)|go:""GO:0004806""(triacylglycerol lipase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0007584""(response to nutrient)|go:""GO:0008201""(heparin binding)|go:""GO:0008970""(phospholipase A1 activity)|go:""GO:0009395""(phospholipid catabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0010983""(positive regulation of high-density lipoprotein particle clearance)|go:""GO:0019433""(triglyceride catabolic process)|go:""GO:0032376""(positive regulation of cholesterol transport)|go:""GO:0034375""(high-density lipoprotein particle remodeling)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0043691""(reverse cholesterol transport)|go:""GO:0050746""(regulation of lipoprotein metabolic process)|go:""GO:0052739""(obsolete phosphatidylserine 1-acylhydrolase activity)|go:""GO:0055091""(phospholipid homeostasis)|interpro:IPR000734(Lipase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR002330(Lipoprotein lipase)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR029058|interpro:IPR033906|interpro:IPR036392|mint:Q9Y5X9|reactome:R-HSA-8964058|refseq:NP_006024.1|refseq:NP_001294935.1|panther:PTHR11610(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR021494|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0030436""(asexual sporulation)|refseq:WP_000669132.1|interpro:IPR036097|interpro:IPR036890|interpro:IPR033479"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:99+JsUIVVhXjBxBSKMkpPcAHUBg9606	rogid:HijQq2WAx6zdkE+eBcC63MZtxRc1392	intact-crc:52E0310328358633|rigid:/d1VeniGa6kX46BYx8VDjoxfphY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IVB5	uniprotkb:A0A2C3GP58	intact:EBI-2830509|uniprotkb:Q6AI36|ensembl:ENSP00000474487.3	intact:EBI-2816674|uniprotkb:Q6I1S1|uniprotkb:Q6KVL0|uniprotkb:E9RBS7|uniprotkb:E9RBS8|uniprotkb:Q81TI7|uniprotkb:A0A0J1HZ47|uniprotkb:A0A1J9VYX6	psi-mi:lix1l_human(display_long)|uniprotkb:LIX1L(gene name)|psi-mi:LIX1L(display_short)	psi-mi:a0a2c3gp58_bacan(display_long)|uniprotkb:GBAA_1284(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830514|imex:IM-13779-3426	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_714924.1|ensembl:ENSG00000271601.4(gene)|ensembl:ENST00000604000.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0097352""(autophagosome maturation)|interpro:IPR029270|interpro:IPR051436|panther:PTHR31139(orthology-group)"	refseq:WP_000251858.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xXI7nPEZf03bSttlySWjLRjf8Vk9606	rogid:nyDoi9UebMTTWZa8V5nJMIU27201392	intact-crc:959B5C3CD2E47619|rigid:TOQfpCh3FYnTTCmhGQXPR5oO1Us	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N423	uniprotkb:A0A6L7HS40	intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960.5|ensembl:ENSP00000375628.1|ensembl:ENSP00000480302.1|ensembl:ENSP00000480841.1|ensembl:ENSP00000481208.1|ensembl:ENSP00000482933.1|ensembl:ENSP00000483014.1|ensembl:ENSP00000483478.1|ensembl:ENSP00000483553.1|ensembl:ENSP00000484373.1|uniprotkb:A2IXV5	intact:EBI-2821815|uniprotkb:Q6KR13|uniprotkb:Q6HWY1|uniprotkb:E9QZ32|uniprotkb:E9QZ33|uniprotkb:Q81NR1	psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym)	psi-mi:a0a6l7hs40_bacan(display_long)|uniprotkb:ppsA(gene name)|psi-mi:ppsA(display_short)|uniprotkb:GBAA_3116(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830539|imex:IM-13779-3427	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-59888N|ensembl:ENSG00000131042.15(gene)|ensembl:ENSG00000274513.4(gene)|ensembl:ENSG00000275463.4(gene)|ensembl:ENSG00000276146.4(gene)|ensembl:ENST00000314446.10(transcript)|ensembl:ENST00000391748.5(transcript)|ensembl:ENST00000610886.4(transcript)|ensembl:ENST00000614225.4(transcript)|ensembl:ENST00000617341.4(transcript)|ensembl:ENST00000617886.4(transcript)|ensembl:ENST00000618392.4(transcript)|ensembl:ENST00000618705.2(transcript)|ensembl:ENST00000619122.3(transcript)|ensembl:ENST00000621020.4(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002578""(negative regulation of antigen processing and presentation)|go:""GO:0002645""(positive regulation of tolerance induction)|go:""GO:0002666""(positive regulation of T cell tolerance induction)|go:""GO:0002764""(immune response-regulating signaling pathway)|go:""GO:0002767""(immune response-inhibiting cell surface receptor signaling pathway)|go:""GO:0002774""(Fc receptor mediated inhibitory signaling pathway)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007611""(learning or memory)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0023025""(MHC class Ib protein complex binding)|go:""GO:0023029""(MHC class Ib protein binding)|go:""GO:0032396""(inhibitory MHC class I receptor activity)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045591""(positive regulation of regulatory T cell differentiation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0051926""(negative regulation of calcium ion transport)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:1900271""(regulation of long-term synaptic potentiation)|go:""GO:1900454""(positive regulation of long-term synaptic depression)|go:""GO:1905875""(negative regulation of postsynaptic density organization)|go:""GO:2000524""(negative regulation of T cell costimulation)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050412|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695|refseq:NP_001074447.2|refseq:NP_001265332.2|refseq:NP_001265333.2|refseq:NP_001265334.2|refseq:NP_001265335.2|refseq:NP_005865.3|panther:PTHR11738(orthology-group)"	"interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR002192(Pyruvate phosphate dikinase, PEP/pyruvate-binding)|go:""GO:0005524""(ATP binding)|go:""GO:0008986""(pyruvate, water dikinase activity)|refseq:WP_000094198.1|interpro:IPR036637|interpro:IPR051549"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8Xo8kAsru21vuhECNL4r9847r3I9606	rogid:+m8pgoZOY+Z0J2aE3uXK/p5DMyE1392	intact-crc:C60B724DD88766F3|rigid:D1noNMHGR8WnNpBcuLuI2Q7WZH0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P7T8	uniprotkb:O75022	intact:EBI-2830530|uniprotkb:Q6KJT1|uniprotkb:Q6HQF6|uniprotkb:E9RD85|uniprotkb:E9RD86|uniprotkb:Q81JV5|uniprotkb:A0A0J1HTV1	intact:EBI-2830524|uniprotkb:Q86U49|uniprotkb:O15471|uniprotkb:C9JIP1|intact:EBI-3453813|uniprotkb:C9J1P3|ensembl:ENSP00000245620.9|ensembl:ENSP00000375630.1|ensembl:ENSP00000479234.1|ensembl:ENSP00000483625.1	psi-mi:a0a6l8p7t8_bacan(display_long)|uniprotkb:Acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:GBAA_5589(locus name)	psi-mi:lirb3_human(display_long)|uniprotkb:LILRB3(gene name)|psi-mi:LILRB3(display_short)|uniprotkb:ILT5(gene name synonym)|uniprotkb:LIR3(gene name synonym)|uniprotkb:CD85 antigen-like family member A(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 5(gene name synonym)|uniprotkb:Monocyte inhibitory receptor HL9(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830521|imex:IM-13779-3429	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020615|interpro:IPR020610|interpro:IPR020617|interpro:IPR020613|interpro:IPR020616|refseq:WP_000047982.1|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)"	"refseq:XP_006726377.1|ensembl:ENSG00000204577.12(gene)|ensembl:ENSG00000274587.5(gene)|ensembl:ENSG00000275019.5(gene)|ensembl:ENST00000245620.13(transcript)|ensembl:ENST00000391750.5(transcript)|ensembl:ENST00000611086.4(transcript)|ensembl:ENST00000613698.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002764""(immune response-regulating signaling pathway)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006952""(defense response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050412|reactome:R-HSA-198933|reactome:R-HSA-6798695|refseq:XP_016885785.1|refseq:XP_016885786.1|panther:PTHR11738(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zp/PX4whwbg1n04GJERgWkIxsuY1392	rogid:m/fh1ou36YQTaovYyLEi47WSy7Q9606	intact-crc:0069BB5D6F69FED2|rigid:Dz0Kw8bOvYBH30IJpDuYtm1m6Lg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N423	uniprotkb:A0A6H3ACS3	intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960.5|ensembl:ENSP00000375628.1|ensembl:ENSP00000480302.1|ensembl:ENSP00000480841.1|ensembl:ENSP00000481208.1|ensembl:ENSP00000482933.1|ensembl:ENSP00000483014.1|ensembl:ENSP00000483478.1|ensembl:ENSP00000483553.1|ensembl:ENSP00000484373.1|uniprotkb:A2IXV5	intact:EBI-2830546|uniprotkb:Q6I3Y9|uniprotkb:Q6KXQ1|uniprotkb:E9R988|uniprotkb:E9R989|uniprotkb:A0A2P0H9H2|uniprotkb:Q81Z49	psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym)	psi-mi:a0a6h3acs3_bacan(display_long)|uniprotkb:GBAA_0424(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830552|imex:IM-13779-3428	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-59888N|ensembl:ENSG00000131042.15(gene)|ensembl:ENSG00000274513.4(gene)|ensembl:ENSG00000275463.4(gene)|ensembl:ENSG00000276146.4(gene)|ensembl:ENST00000314446.10(transcript)|ensembl:ENST00000391748.5(transcript)|ensembl:ENST00000610886.4(transcript)|ensembl:ENST00000614225.4(transcript)|ensembl:ENST00000617341.4(transcript)|ensembl:ENST00000617886.4(transcript)|ensembl:ENST00000618392.4(transcript)|ensembl:ENST00000618705.2(transcript)|ensembl:ENST00000619122.3(transcript)|ensembl:ENST00000621020.4(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002578""(negative regulation of antigen processing and presentation)|go:""GO:0002645""(positive regulation of tolerance induction)|go:""GO:0002666""(positive regulation of T cell tolerance induction)|go:""GO:0002764""(immune response-regulating signaling pathway)|go:""GO:0002767""(immune response-inhibiting cell surface receptor signaling pathway)|go:""GO:0002774""(Fc receptor mediated inhibitory signaling pathway)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006968""(cellular defense response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007611""(learning or memory)|go:""GO:0008157""(protein phosphatase 1 binding)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0023025""(MHC class Ib protein complex binding)|go:""GO:0023029""(MHC class Ib protein binding)|go:""GO:0032396""(inhibitory MHC class I receptor activity)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045591""(positive regulation of regulatory T cell differentiation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051248""(negative regulation of protein metabolic process)|go:""GO:0051926""(negative regulation of calcium ion transport)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:1900271""(regulation of long-term synaptic potentiation)|go:""GO:1900454""(positive regulation of long-term synaptic depression)|go:""GO:1905875""(negative regulation of postsynaptic density organization)|go:""GO:2000524""(negative regulation of T cell costimulation)|go:""GO:2001198""(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050412|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695|refseq:NP_001074447.2|refseq:NP_001265332.2|refseq:NP_001265333.2|refseq:NP_001265334.2|refseq:NP_001265335.2|refseq:NP_005865.3|panther:PTHR11738(orthology-group)"	"interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR002509(Polysaccharide deacetylase)|interpro:IPR014235(Delta-lactam-biosynthetic de-N-acetylase)|rcsb pdb:2J13|refseq:WP_000681209.1|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0016810""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"")|go:""GO:0046872""(metal ion binding)|interpro:IPR050248"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8Xo8kAsru21vuhECNL4r9847r3I9606	rogid:0h9S3BD4l6F8yFSnawYHpv7qrag1392	intact-crc:4D665221768B265B|rigid:CbSyfQXMPZseNEqsAMEpJJCLy0I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96PV6	uniprotkb:A0A6L7H9C3	intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|ensembl:ENSP00000318374.5|ensembl:ENSP00000478337.1|ensembl:ENSP00000478975.1|ensembl:ENSP00000480663.1|intact:EBI-28984630|uniprotkb:A0A087WTE7	intact:EBI-2812297|uniprotkb:Q6KK92|uniprotkb:Q6HQX4|uniprotkb:E9R1I9|uniprotkb:E9R1J0|uniprotkb:Q81X37|uniprotkb:A0A1Q4LY85	psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym)	psi-mi:a0a6l7h9c3_bacan(display_long)|uniprotkb:GBAA_5406(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830601|imex:IM-13779-3433	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_443157.1|refseq:XP_011524717.1|ensembl:ENSG00000167615.18(gene)|ensembl:ENSG00000274305.4(gene)|ensembl:ENSG00000276458.4(gene)|ensembl:ENSG00000276681.4(gene)|ensembl:ENST00000326764.10(transcript)|ensembl:ENST00000617180.4(transcript)|ensembl:ENST00000621306.4(transcript)|ensembl:ENST00000622672.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0032991""(protein-containing complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR045107|mint:Q96PV6|panther:PTHR12436(orthology-group)"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|refseq:WP_001099975.1|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kwgKuV5NW0hITukndsYeyQHTdd09606	rogid:RF415biCLiP0aJnqIsNwQXl5DRw1392	intact-crc:9B8F689B90387918|rigid:m8uHxi7UpqcjDEKp4aNNC5Wtt8I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96PV6	uniprotkb:Q81ME0	intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|ensembl:ENSP00000318374.5|ensembl:ENSP00000478337.1|ensembl:ENSP00000478975.1|ensembl:ENSP00000480663.1|intact:EBI-28984630|uniprotkb:A0A087WTE7	intact:EBI-2813646|uniprotkb:Q6KN28|uniprotkb:Q6HTU1	psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym)	psi-mi:deob_bacan(display_long)|uniprotkb:deoB(gene name)|psi-mi:deoB(display_short)|uniprotkb:Phosphodeoxyribomutase(gene name synonym)|uniprotkb:BA_4309(locus name)|uniprotkb:GBAA_4309(locus name)|uniprotkb:BAS3997(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830587|imex:IM-13779-3434	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_443157.1|refseq:XP_011524717.1|ensembl:ENSG00000167615.18(gene)|ensembl:ENSG00000274305.4(gene)|ensembl:ENSG00000276458.4(gene)|ensembl:ENSG00000276681.4(gene)|ensembl:ENST00000326764.10(transcript)|ensembl:ENST00000617180.4(transcript)|ensembl:ENST00000621306.4(transcript)|ensembl:ENST00000622672.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0032991""(protein-containing complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR045107|mint:Q96PV6|panther:PTHR12436(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR010045(Phosphopentomutase)|interpro:IPR006124(Metalloenzyme)|interpro:IPR024052|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006015""(5-phosphoribose 1-diphosphate biosynthetic process)|go:""GO:0006018""(2-deoxyribose 1-phosphate catabolic process)|go:""GO:0008973""(phosphopentomutase activity)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0043094""(metabolic compound salvage)|refseq:WP_001046068.1|refseq:NP_846542.1|refseq:YP_030247.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kwgKuV5NW0hITukndsYeyQHTdd09606	rogid:4rSH7u8wKFseFpqFRuqEYAYDNTo1392	intact-crc:D75E5F328A04CF16|rigid:Mm1FjryCxdWmTKrgxqQYyJitN3g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H400	uniprotkb:Q81TW1	intact:EBI-2830566|uniprotkb:Q5JWJ2|uniprotkb:Q9NX69|uniprotkb:Q6XYB3|uniprotkb:E1P5K5|uniprotkb:E1P5K6|ensembl:ENSP00000309521.3	intact:EBI-2810929|uniprotkb:Q6I247|uniprotkb:Q6KVY3	psi-mi:lime1_human(display_long)|uniprotkb:LIME1(gene name)|psi-mi:LIME1(display_short)|uniprotkb:LIME(gene name synonym)|uniprotkb:Lck-interacting molecule(gene name synonym)|uniprotkb:LP8067(orf name)	psi-mi:adda_bacan(display_long)|uniprotkb:addA(gene name)|psi-mi:addA(display_short)|uniprotkb:DNA 3'-5' helicase AddA(gene name synonym)|uniprotkb:BAS1061(locus name)|uniprotkb:BA_1142(locus name)|uniprotkb:GBAA_1142(locus name)|uniprotkb:ATP-dependent helicase/nuclease AddA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830573|imex:IM-13779-3435	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001292583.1|refseq:NP_001292584.1|refseq:NP_060276.2|ensembl:ENSG00000203896.10(gene)|ensembl:ENST00000309546.8(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005615""(extracellular space)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0019815""(B cell receptor complex)|go:""GO:0019901""(protein kinase binding)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0051279""(regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051896""(regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:1901222""(regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR026072|panther:PTHR47740(orthology-group)"	"interpro:IPR014152(""DNA helicase (recombination ), AddA type"")|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR038726|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0033202""(DNA helicase complex)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|refseq:WP_000970458.1|refseq:NP_843626.1|refseq:YP_027333.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qDnQj4e1W9MQHJiwn7R0np/XU6E9606	rogid:mjbRVJQHL4JcpSJqsALgvEqgiMk1392	intact-crc:59F105E147282F2F|rigid:LD/6MWmv6UWm+MCiExlFL3Ut2Pw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81JW1	uniprotkb:Q96PV6	intact:EBI-2816384|uniprotkb:Q6KJT7|uniprotkb:Q6HQG2	intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|ensembl:ENSP00000318374.5|ensembl:ENSP00000478337.1|ensembl:ENSP00000478975.1|ensembl:ENSP00000480663.1|intact:EBI-28984630|uniprotkb:A0A087WTE7	psi-mi:pyrg_bacan(display_long)|uniprotkb:pyrG(gene name)|psi-mi:pyrG(display_short)|uniprotkb:ctrA(gene name synonym)|uniprotkb:UTP--ammonia ligase(gene name synonym)|uniprotkb:BA_5583(locus name)|uniprotkb:GBAA_5583(locus name)|uniprotkb:BAS5187(locus name)|uniprotkb:Cytidine 5'-triphosphate synthase(gene name synonym)|uniprotkb:Cytidine triphosphate synthetase(gene name synonym)	psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830594|imex:IM-13779-3432	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR029062|interpro:IPR027417|go:""GO:0003883""(CTP synthase activity)|go:""GO:0004359""(glutaminase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019856""(pyrimidine nucleobase biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0044210""('de novo' CTP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000170456.1|interpro:IPR033828|refseq:NP_847739.1|refseq:YP_031426.1"	"refseq:NP_443157.1|refseq:XP_011524717.1|ensembl:ENSG00000167615.18(gene)|ensembl:ENSG00000274305.4(gene)|ensembl:ENSG00000276458.4(gene)|ensembl:ENSG00000276681.4(gene)|ensembl:ENST00000326764.10(transcript)|ensembl:ENST00000617180.4(transcript)|ensembl:ENST00000621306.4(transcript)|ensembl:ENST00000622672.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0032991""(protein-containing complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR045107|mint:Q96PV6|panther:PTHR12436(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SrGr2YO98Kx1ur7cTIL31MeRXwk1392	rogid:kwgKuV5NW0hITukndsYeyQHTdd09606	intact-crc:59BE08328A5D47F0|rigid:afeMUncqWNcKFEWug/hbCu99VJM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PG14	uniprotkb:Q9UGP4	intact:EBI-2816470|uniprotkb:Q6HX09|uniprotkb:Q6KR38|uniprotkb:E9R0S7|uniprotkb:E9R0S8|uniprotkb:Q81NT8|uniprotkb:A0A1S0QR24	intact:EBI-2652871|uniprotkb:Q17RQ1|uniprotkb:Q9BQQ9|uniprotkb:Q9NQ47|ensembl:ENSP00000273317.4	psi-mi:a0a6l8pg14_bacan(display_long)|uniprotkb:lepB(gene name)|psi-mi:lepB(display_short)|uniprotkb:GBAA_3086(locus name)	psi-mi:limd1_human(display_long)|uniprotkb:LIMD1(gene name)|psi-mi:LIMD1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830580|imex:IM-13779-3431	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000223(Peptidase S26A, signal peptidase I)|interpro:IPR019758|interpro:IPR019757|interpro:IPR019756|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006465""(signal peptide processing)|refseq:WP_000806883.1|interpro:IPR036286|interpro:IPR019533"	"refseq:NP_055055.1|ensembl:ENSG00000144791.10(gene)|ensembl:ENST00000273317.5(transcript)|go:""GO:0000932""(P-body)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002076""(osteoblast development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0016310""(phosphorylation)|go:""GO:0016442""(RISC complex)|go:""GO:0016477""(cell migration)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0035331""(negative regulation of hippo signaling)|go:""GO:0045668""(negative regulation of osteoblast differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR047172|interpro:IPR047245|interpro:IPR047247|interpro:IPR047248|mint:Q9UGP4|reactome:R-HSA-1234176|panther:PTHR24219(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2Tuuq9p0hJFVgtMENIDyNsSoO9I1392	rogid:Eq6aJ83PR4G/LIlUi5H2Bv31sTQ9606	intact-crc:7CBC2B7CA4A8957D|rigid:7F2/y4svseM16WH+/oSoNERflu8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PGF9	uniprotkb:P17931	intact:EBI-2812067|uniprotkb:Q6HZF5|uniprotkb:Q6KTE4|uniprotkb:E9R4G8|uniprotkb:E9R4G9|uniprotkb:Q81R82|uniprotkb:A0A0F7RIG7	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:a0a6l8pgf9_bacan(display_long)|uniprotkb:GBAA_2174(locus name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830615|imex:IM-13779-3439	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007536(Protein of unknown function DUF548)|interpro:IPR029063|go:""GO:0008990""(""rRNA (guanine-N2-)-methyltransferase activity"")|refseq:WP_000637445.1"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:9J88Y78eGq6GLkPj6dvcpx+fMzY1392	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:59512296577410D2|rigid:GDKYAVUG5KowNa9+BAHcMJ/0Ggg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PG50	uniprotkb:Q96PV6	intact:EBI-2826338|uniprotkb:Q6KPT3|uniprotkb:Q6HVL7|uniprotkb:E9R6N8|uniprotkb:E9R6N9|uniprotkb:Q81YC4|uniprotkb:A0A0F7REF0	intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|ensembl:ENSP00000318374.5|ensembl:ENSP00000478337.1|ensembl:ENSP00000478975.1|ensembl:ENSP00000480663.1|intact:EBI-28984630|uniprotkb:A0A087WTE7	psi-mi:a0a6l8pg50_bacan(display_long)|uniprotkb:fdhD2(gene name)|psi-mi:fdhD2(display_short)|uniprotkb:fdhD(gene name synonym)|uniprotkb:GBAA_3628(locus name)	psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830608|imex:IM-13779-3436	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003786(Formate dehydrogenase, subunit FdhD)|interpro:IPR016193(Cytidine deaminase-like)|go:""GO:0005737""(cytoplasm)|go:""GO:0006777""(Mo-molybdopterin cofactor biosynthetic process)|go:""GO:0016783""(sulfurtransferase activity)|go:""GO:0097163""(sulfur carrier activity)|refseq:WP_000802671.1"	"refseq:NP_443157.1|refseq:XP_011524717.1|ensembl:ENSG00000167615.18(gene)|ensembl:ENSG00000274305.4(gene)|ensembl:ENSG00000276458.4(gene)|ensembl:ENSG00000276681.4(gene)|ensembl:ENST00000326764.10(transcript)|ensembl:ENST00000617180.4(transcript)|ensembl:ENST00000621306.4(transcript)|ensembl:ENST00000622672.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0032991""(protein-containing complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|interpro:IPR045107|mint:Q96PV6|panther:PTHR12436(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qqHZe3PD0Gzi9adj/UXqI0JmiZQ1392	rogid:kwgKuV5NW0hITukndsYeyQHTdd09606	intact-crc:98F43B48219E9BC8|rigid:roZfP+G6aLRUMSwhH22gAqQrwxQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A3P1UEK7	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2819119|uniprotkb:Q6KLZ5|uniprotkb:E9QV12|uniprotkb:Q81L99	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:a0a3p1uek7_bacan(display_long)|uniprotkb:GBAA_4727(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830622|imex:IM-13779-3437	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR032466|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:WP_001178581.1|go:""GO:0016814""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines"")|interpro:IPR013108(Amidohydrolase 3)|interpro:IPR052349"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:nYURAzycKK966oKi5Sz7z8ZWOf41392	intact-crc:5CC2770F991F4485|rigid:MZXUoWRx+/R3+Ls3Sc1S1huQ9oU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:Q81SR4	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2815297|uniprotkb:Q6KUV0|uniprotkb:Q6I0Z6	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:y1582_bacan(display_long)|uniprotkb:BA_1582(locus name)|uniprotkb:GBAA_1582(locus name)|uniprotkb:BAS1466(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830636|imex:IM-13779-3440	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	interpro:IPR010697(Protein of unknown function DUF1273)|refseq:WP_000862924.1|refseq:NP_844031.1|refseq:YP_027735.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:kRkzWueeQf18LltGErdS4DVGq+M1392	intact-crc:35A848ED475687DB|rigid:TFdY48pDigc5ybC4nhP6XxHMpyw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:Q81S14	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2811794|uniprotkb:Q6I094|uniprotkb:Q6KU68	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:mtad_bacan(display_long)|uniprotkb:mtaD(gene name)|psi-mi:mtaD(display_short)|uniprotkb:BA_1865(locus name)|uniprotkb:GBAA_1865(locus name)|uniprotkb:BAS1729(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830629|imex:IM-13779-3438	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR023512|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR050287|go:""GO:0046872""(metal ion binding)|go:""GO:0050270""(S-adenosylhomocysteine deaminase activity)|go:""GO:0090614""(5'-methylthioadenosine deaminase activity)|interpro:IPR032466|refseq:NP_844282.1|refseq:YP_027994.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:TDYnZJrYplZEtZNuGj+DQVH3gl81392	intact-crc:9E7B48ED47415D04|rigid:WNQ5NusGYcQ0+RnPHgdlaP932eA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A6L8PTT5	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2810562|uniprotkb:Q6HVR1|uniprotkb:Q6KPX8|uniprotkb:E9R792|uniprotkb:E9R793|uniprotkb:Q81YG8|uniprotkb:A0A0F7REJ1	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:a0a6l8ptt5_bacan(display_long)|uniprotkb:GBAA_3581(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830643|imex:IM-13779-3445	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR000653(DegT/DnrJ/EryC1/StrS aminotransferase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:""GO:0000271""(polysaccharide biosynthetic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:WP_001084732.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:Q0pKzwIux3ytDFlAgGr8eyehbos1392	intact-crc:45A16540012415CB|rigid:Sho08glwY06uwufcVchVPcQMwBU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A6L7HAI8	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2830660|uniprotkb:Q6I022|uniprotkb:Q6KU01|uniprotkb:E9QW38|uniprotkb:E9QW39|uniprotkb:A0A2P0HD33|uniprotkb:Q81RU5	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:a0a6l7hai8_bacan(display_long)|uniprotkb:GBAA_1942(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830657|imex:IM-13779-3444	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR011251(Bacterial luciferase-like)|refseq:WP_000417587.1|go:""GO:0004497""(monooxygenase activity)|go:""GO:0005829""(cytosol)|go:""GO:0016705""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|interpro:IPR036661|interpro:IPR050766"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:8SP1qLe2LbiZz1PhuHzMU485vBg1392	intact-crc:1D9367285D4FCEEA|rigid:WC+GLtx7bP/zq0kAaumA4yvRIJc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:Q81QB6	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2813022|uniprotkb:Q6KSJ4|uniprotkb:Q6HYJ3	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:iola2_bacan(display_long)|uniprotkb:iolA2(gene name)|psi-mi:iolA2(display_short)|uniprotkb:Methylmalonate-semialdehyde dehydrogenase 2(gene name synonym)|uniprotkb:BAS2334(locus name)|uniprotkb:BA_2513(locus name)|uniprotkb:GBAA_2513(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830676|imex:IM-13779-3443	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR010061(Methylmalonate-semialdehyde dehydrogenase)|interpro:IPR023510|go:""GO:0004491""(""methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"")|go:""GO:0006210""(thymine catabolic process)|go:""GO:0006574""(valine catabolic process)|go:""GO:0018478""(""malonate-semialdehyde dehydrogenase (acetylating) activity"")|go:""GO:0019310""(inositol catabolic process)|refseq:WP_000218128.1|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:NP_844885.1|refseq:YP_028595.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:TaEXSia0nVVJlDhMy7qd6AdehPI1392	intact-crc:E102AAED47EAB667|rigid:nm+0MVIaoUP5N5jws4NyHpcOI94	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A6H3AES4	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2811324|uniprotkb:Q6HYW1|uniprotkb:Q6KSV8|uniprotkb:E9RCE1|uniprotkb:E9RCE2|uniprotkb:Q81QN9|uniprotkb:A0A0F7RE93	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:a0a6h3aes4_bacan(display_long)|uniprotkb:GBAA_2380(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830669|imex:IM-13779-3442	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR054399|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR023827|interpro:IPR023828|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR050131|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|refseq:WP_000790944.1|interpro:IPR034084|interpro:IPR036852"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:GIz9JENfwf7NponUkIqm1coWxy81392	intact-crc:5FBEDE60FE21B258|rigid:xI6thnU73Lbnu3EFXhWEPi+R3kA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H7Q9	uniprotkb:P17931	intact:EBI-2823444|uniprotkb:Q6KJD7|uniprotkb:Q6I2U5|uniprotkb:E9R5Y4|uniprotkb:E9R5Y5|uniprotkb:Q81UL4|uniprotkb:A0A0F7RMR7	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:a0a6l7h7q9_bacan(display_long)|uniprotkb:GBAA_0852(locus name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830650|imex:IM-13779-3441	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039421|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015421""(ABC-type oligopeptide transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000493196.1|interpro:IPR036640"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:I2iOFxwdUv+WSyGorI6ZN5h40hs1392	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:7915A2356BC47394|rigid:ykDcV39fNyri00VelZNWTli1DwA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A6L8Q050	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2812424|uniprotkb:Q6HS63|uniprotkb:Q6F089|uniprotkb:E9RAL4|uniprotkb:E9RAL5|uniprotkb:Q81KQ7|uniprotkb:A0A0F7RCB3	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:a0a6l8q050_bacan(display_long)|uniprotkb:GBAA_4933(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830690|imex:IM-13779-3449	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR035097|interpro:IPR000787(Peptidase M29, aminopeptidase II)|interpro:IPR052170|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_000654736.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:Ca6ZxzgWZSbnRiXpfkXmNm3rVl01392	intact-crc:D99B5E97744DB86A|rigid:3fQGy4+AtA1Ck2g9O85J6SqzEVs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WU4	uniprotkb:P07195	intact:EBI-2830714|uniprotkb:Q6KP72|uniprotkb:Q6HUZ7	intact:EBI-358748|ensembl:ENSP00000229319.1|ensembl:ENSP00000379386.1	psi-mi:pept_bacan(display_long)|uniprotkb:pepT(gene name)|psi-mi:pepT(display_short)|uniprotkb:pepT-1(gene name synonym)|uniprotkb:Aminotripeptidase(gene name synonym)|uniprotkb:Tripeptide aminopeptidase(gene name synonym)|uniprotkb:BA_3872(locus name)|uniprotkb:GBAA_3872(locus name)|uniprotkb:BAS3588(locus name)	psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830711|imex:IM-13779-3450	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR010161(Peptidase M20B, tripeptide aminopeptidase)|rcsb pdb:3IFE|refseq:WP_000656974.1|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0045148""(tripeptide aminopeptidase activity)|interpro:IPR036264|refseq:NP_846121.1|refseq:YP_029841.1"	"ensembl:ENSG00000111716.14(gene)|ensembl:ENST00000350669.5(transcript)|ensembl:ENST00000396076.5(transcript)|go:""GO:0004459""(L-lactate dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0019674""(NAD metabolic process)|go:""GO:0019900""(kinase binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045121""(membrane raft)|go:""GO:0051287""(NAD binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1990204""(oxidoreductase complex)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|rcsb pdb:7DBJ|rcsb pdb:7DBK|rcsb pdb:8QDE|reactome:R-HSA-70268|refseq:NP_001167568.1|refseq:NP_001302466.1|refseq:NP_002291.1|efo:""Orphanet:284435""|panther:PTHR43128(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Oha1BGkI+0d8YvKh6DtzsAuCnYs1392	rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606	intact-crc:CBCEFE429A2C5A3D|rigid:FVT9dUmyR+HyC2R/BIEBTItlH/s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A6L7H8R9	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2815590|uniprotkb:Q6HQ18|uniprotkb:Q6KJG2|uniprotkb:E9R6J0|uniprotkb:E9R6J1|uniprotkb:Q81JH6|uniprotkb:A0A1J9VHM6|uniprotkb:A0A2B3XZ06	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:a0a6l7h8r9_bacan(display_long)|uniprotkb:GBAA_5730(locus name)|uniprotkb:soJ(gene name)|psi-mi:soJ(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830704|imex:IM-13779-3448	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	interpro:IPR025669|interpro:IPR027417|interpro:IPR050678|refseq:WP_000516114.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:/DKHcmTkGiZkSA4a2dRb26Q5AmY1392	intact-crc:46467362523AB4AD|rigid:T3RLujNHKnRPNHU6jZzWYJx3+OM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7GZX4	uniprotkb:P17931	intact:EBI-2818035|uniprotkb:Q6KMW3|uniprotkb:Q6HTM2|uniprotkb:E9QTC4|uniprotkb:E9QTC5|uniprotkb:Q81M70|uniprotkb:A0A1S0QNL6|uniprotkb:A0A2P0HIQ4	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	psi-mi:a0a6l7gzx4_bacan(display_long)|uniprotkb:GBAA_4383(locus name)|uniprotkb:bfmbAb(gene name)|psi-mi:bfmbAb(display_short)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830683|imex:IM-13779-3446	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000290076.1|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR033248|interpro:IPR029061|go:""GO:0003863""(""3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity"")"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:derx46kNWSsVeVC9yesQ0Jn+pn01392	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	intact-crc:95ABA34173370B1B|rigid:35rSpaQgT2JCFKDQn334J5YcFUc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17931	uniprotkb:A0A6L8PTK5	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301.9	intact:EBI-2815740|uniprotkb:Q6KLC6|uniprotkb:Q6HS22|uniprotkb:E9R820|uniprotkb:E9R821|uniprotkb:Q81KM0|uniprotkb:A0A0F7R5G6	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:a0a6l8ptk5_bacan(display_long)|uniprotkb:GBAA_4976(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830697|imex:IM-13779-3447	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002297.2|panther:PTHR11346(orthology-group)|dip:DIP-45623N|ensembl:ENSG00000131981.16(gene)|ensembl:ENST00000254301.14(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0002548""(monocyte chemotaxis)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019863""(IgE binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030246""(carbohydrate binding)|go:""GO:0030547""(signaling receptor inhibitor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0042056""(chemoattractant activity)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043236""(laminin binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045806""(negative regulation of endocytosis)|go:""GO:0048030""(disaccharide binding)|go:""GO:0048245""(eosinophil chemotaxis)|go:""GO:0048246""(macrophage chemotaxis)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051134""(negative regulation of NK T cell activation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070232""(regulation of T cell apoptotic process)|go:""GO:0071674""(mononuclear cell migration)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0090280""(positive regulation of calcium ion import)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0141069""(receptor ligand inhibitor activity)|go:""GO:1902041""(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:2000521""(negative regulation of immunological synapse formation)|go:""GO:2001189""(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7CXA|rcsb pdb:7DF5|rcsb pdb:7RDO|rcsb pdb:7RDP|rcsb pdb:7RGX|rcsb pdb:7RGY|rcsb pdb:7RGZ|rcsb pdb:7RH0|rcsb pdb:7RH1|rcsb pdb:7RH3|rcsb pdb:7RH4|rcsb pdb:7XFA|rcsb pdb:7ZQX|rcsb pdb:8BZ3|rcsb pdb:8ITX|rcsb pdb:8ITZ|rcsb pdb:8OJI|rcsb pdb:8OJK|rcsb pdb:8OJM|rcsb pdb:8OJO|rcsb pdb:8PBF|rcsb pdb:8PF9|rcsb pdb:8PFF|rcsb pdb:8PPN|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333"	"interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0008146""(sulfotransferase activity)|go:""GO:0008641""(ubiquitin-like modifier activating enzyme activity)|go:""GO:0016779""(nucleotidyltransferase activity)|refseq:WP_001158094.1|interpro:IPR035985|interpro:IPR045886"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rogid:uDGO+gtg3zkc7kwxZa3vzDK2sII1392	intact-crc:86A618EE42C9BB8F|rigid:1pjmo4Ac+2SP29uQYjUN7f950wg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H1G2	uniprotkb:Q4G0J3	intact:EBI-2809927	intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-25601393|intact:EBI-2560173|ensembl:ENSP00000344950.5|ensembl:ENSP00000421541.2|ensembl:ENSP00000422626.2|ensembl:ENSP00000499190.1|ensembl:ENSP00000511572.1	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830738|imex:IM-13779-3454	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"ensembl:ENSG00000174720.18(gene)|ensembl:ENST00000344442.10(transcript)|ensembl:ENST00000505034.6(transcript)|ensembl:ENST00000509061.5(transcript)|ensembl:ENST00000651579.1(transcript)|ensembl:ENST00000694894.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000494""(""box C/D sno(s)RNA 3'-end processing"")|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008380""(RNA splicing)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0097322""(7SK snRNA binding)|go:""GO:0120259""(7SK snRNP)|go:""GO:1904871""(positive regulation of protein localization to Cajal body)|go:""GO:1905382""(positive regulation of snRNA transcription by RNA polymerase II)|go:""GO:1990438""(U6 2'-O-snRNA methylation)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12|rcsb pdb:7SLP|rcsb pdb:7SLQ|refseq:NP_001253968.1|refseq:NP_056269.1|refseq:NP_057732.2|dip:DIP-47624N|efo:""Orphanet:319671""|panther:PTHR22792(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606	intact-crc:0F2AC0210D6F01D4|rigid:AgsnAndmdVvHcbmQHcWUTrHe4qg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y383	uniprotkb:Q81NN0	intact:EBI-352851|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500|ensembl:ENSP00000347005.4	intact:EBI-2820443|uniprotkb:Q6KQY6|uniprotkb:Q6HWU8	psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name)	psi-mi:glsa2_bacan(display_long)|uniprotkb:glsA2(gene name)|psi-mi:glsA2(display_short)|uniprotkb:glsA-2(gene name synonym)|uniprotkb:BA_3155(locus name)|uniprotkb:GBAA_3155(locus name)|uniprotkb:BAS2932(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830731|imex:IM-13779-3451	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|ensembl:ENSG00000146963.18(gene)|ensembl:ENST00000354926.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005685""(U1 snRNP)|go:""GO:0006376""(mRNA splice site recognition)|go:""GO:0016607""(nuclear speck)|go:""GO:0019899""(enzyme binding)|go:""GO:0071004""(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|dip:DIP-32513N|panther:PTHR12375(orthology-group)"	"refseq:WP_000588653.1|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|go:""GO:0004359""(glutaminase activity)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006543""(glutamine catabolic process)|refseq:NP_845472.1|refseq:YP_029190.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606	rogid:BIz9rHS/CqwS+6izEipBr6bK2H01392	intact-crc:4CAB4220F16A83EC|rigid:QZmaH7IRH/p1f2i4oDE2q3THlFA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PF80	uniprotkb:Q6PKG0	intact:EBI-2818608|uniprotkb:Q6KV34|uniprotkb:Q6I184|uniprotkb:E9R7Q9|uniprotkb:E9R7R0|uniprotkb:Q81T03|uniprotkb:A0A1Q4M3M2	intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589.2	psi-mi:a0a6l8pf80_bacan(display_long)|uniprotkb:GBAA_1489(locus name)	psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830745|imex:IM-13779-3452	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000082669.1|interpro:IPR019832|interpro:IPR019831|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019833|go:""GO:0004784""(superoxide dismutase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR050265|interpro:IPR036314|interpro:IPR036324"	"refseq:NP_056130.2|refseq:XP_005268461.1|ensembl:ENSG00000155506.19(gene)|ensembl:ENST00000518297.6(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0008190""(eukaryotic initiation factor 4E binding)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008494""(translation activator activity)|rcsb pdb:5C0V|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0031929""(TOR signaling)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0072752""(cellular response to rapamycin)|go:""GO:1990928""(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3|rcsb pdb:7SOO|rcsb pdb:7SOP|rcsb pdb:7SOQ|rcsb pdb:7SOR|rcsb pdb:7SOS|rcsb pdb:7SOT|rcsb pdb:7SOU|rcsb pdb:7SOV|rcsb pdb:7SOW|rcsb pdb:8EY6|rcsb pdb:8EY7|rcsb pdb:8EY8|rcsb pdb:8G90|rcsb pdb:8G91|reactome:R-HSA-9705671|panther:PTHR22792(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mymm6dxlxGf4m+VlU4uxZfJJ6C41392	rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606	intact-crc:FDBEB4470E61B99C|rigid:oRLiDaEjeJ7zocdgJWF+er0tsvo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86U70	uniprotkb:Q81TK1	intact:EBI-677177|uniprotkb:O75479|uniprotkb:O96010|uniprotkb:Q1EQX1|uniprotkb:Q9UGM4|uniprotkb:B4DUC4|ensembl:ENSP00000501277.1	intact:EBI-2819816|uniprotkb:Q6KVM3|uniprotkb:Q6I1T3	psi-mi:ldb1_human(display_long)|uniprotkb:Nuclear LIM interactor(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:LDB1(gene name)|psi-mi:LDB1(display_short)|uniprotkb:CLIM2(gene name synonym)	psi-mi:odo1_bacan(display_long)|uniprotkb:odhA(gene name)|psi-mi:odhA(display_short)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:BA_1270(locus name)|uniprotkb:GBAA_1270(locus name)|uniprotkb:BAS1177(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830724|imex:IM-13779-3455	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001106878.1|refseq:NP_003884.1|ensembl:ENSG00000198728.11(gene)|ensembl:ENST00000673968.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000972""(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:""GO:0001702""(gastrulation with mouth forming second)|go:""GO:0001942""(hair follicle development)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007155""(cell adhesion)|go:""GO:0007399""(nervous system development)|go:""GO:0009948""(anterior/posterior axis specification)|go:""GO:0010669""(epithelial structure maintenance)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0021702""(cerebellar Purkinje cell differentiation)|go:""GO:0022607""(cellular component assembly)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030274""(LIM domain binding)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0031252""(cell leading edge)|go:""GO:0032968""(positive regulation of transcription elongation by RNA polymerase II)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043549""(regulation of kinase activity)|go:""GO:0045647""(negative regulation of erythrocyte differentiation)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046985""(positive regulation of hemoglobin biosynthetic process)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1990907""(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR041363|mint:Q86U70|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:6TYD|rcsb pdb:7OB5|rcsb pdb:7OB8|rcsb pdb:8HIB|rcsb pdb:8SSU|rcsb pdb:9F5B|reactome:R-HSA-8939236|reactome:R-HSA-9010553|reactome:R-HSA-9733709|reactome:R-HSA-9752946|dip:DIP-31826N|panther:PTHR10378(orthology-group)"	"interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR023784|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR029061|go:""GO:0004591""(""oxoglutarate dehydrogenase (succinyl-transferring) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006096""(glycolytic process)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0045252""(oxoglutarate dehydrogenase complex)|refseq:WP_000197146.1|interpro:IPR031717|interpro:IPR042179|refseq:NP_843742.1|refseq:YP_027447.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:qvQKQuFDKim15gEBFj6MnxR6lTc9606	rogid:8Loo3rMq41/Gg3LofhIbmnjb+1s1392	intact-crc:59021C52D54E1349|rigid:8+1BprcLzzVrfP4IDQ+FE8VLK5Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PPL7	uniprotkb:P18627	intact:EBI-2820855|uniprotkb:Q6KKI9|uniprotkb:Q6HR71|uniprotkb:E9QYW1|uniprotkb:E9QYW2|uniprotkb:A0A2P0HL78|uniprotkb:Q81XD7	intact:EBI-2830752|uniprotkb:A8K7T9|uniprotkb:Q7Z643|ensembl:ENSP00000203629.2	psi-mi:a0a6l8ppl7_bacan(display_long)|uniprotkb:GBAA_5302(locus name)	psi-mi:lag3_human(display_long)|uniprotkb:LAG3(gene name)|psi-mi:LAG3(display_short)|uniprotkb:FDC(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830757|imex:IM-13779-3453	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016040(""NAD(P)-binding"")|go:""GO:0016646""(oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor)|refseq:WP_000689817.1|interpro:IPR036291|interpro:IPR051606"	"refseq:NP_002277.4|ensembl:ENSG00000089692.9(gene)|ensembl:ENST00000203629.3(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002270""(plasmacytoid dendritic cell activation)|go:""GO:0003823""(antigen binding)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0042110""(T cell activation)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045590""(negative regulation of regulatory T cell differentiation)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0050776""(regulation of immune response)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR036179|rcsb pdb:7TZG|rcsb pdb:7TZH|rcsb pdb:7UM3|rcsb pdb:8SO3|rcsb pdb:8SR0|reactome:R-HSA-2132295|panther:PTHR11890(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1k4lxbZKPNfPGD/o4O59XbFC4EM1392	rogid:LKgdGAeEExS57wqpGF8zyU2ODEw9606	intact-crc:9AF9629FB90AAB24|rigid:KZfbTYVjZ+jUQZ4UZTq0lknBsC4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HKT5	uniprotkb:Q9UNZ5	intact:EBI-2830360|uniprotkb:Q6HZ84|uniprotkb:Q6KT77|uniprotkb:E9R634|uniprotkb:E9R635|uniprotkb:A0A2P0HDM4|uniprotkb:Q81R13	intact:EBI-2830764|uniprotkb:B2R4J9|ensembl:ENSP00000465432.1	psi-mi:a0a6l7hkt5_bacan(display_long)|uniprotkb:GBAA_2246(locus name)	psi-mi:l10k_human(display_long)|uniprotkb:C19orf53(gene name)|psi-mi:C19orf53(display_short)|uniprotkb:HSPC023(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830790|imex:IM-13779-3460	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003797(DegV)|refseq:WP_003169578.1|go:""GO:0008289""(lipid binding)|interpro:IPR043168|interpro:IPR050270"	refseq:NP_054766.1|ensembl:ENSG00000104979.9(gene)|ensembl:ENST00000588234.6(transcript)|interpro:IPR019034|mint:Q9UNZ5|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLC|rcsb pdb:8IDT|rcsb pdb:8IDY|rcsb pdb:8INE|rcsb pdb:8INF|dip:DIP-61980N|panther:PTHR16967(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/20	rogid:H8TGMy9xiNOxV8gWP7WTK7KRoBM1392	rogid:Mdy8NfyuLddMoZlWKmEicxOuM109606	intact-crc:7558A91AA7A51A1C|rigid:DxFd/ZEURpZ0A6xk3T50sa24sXs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PC29	uniprotkb:Q6PKG0	intact:EBI-2810801|uniprotkb:Q6KRM4|uniprotkb:Q6HXJ8|uniprotkb:E9QRE3|uniprotkb:E9QRE4|uniprotkb:A0A2P0HF49|uniprotkb:Q81PD4	intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589.2	psi-mi:a0a6l8pc29_bacan(display_long)|uniprotkb:GBAA_2876(locus name)	psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830776|imex:IM-13779-3459	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001062740.1	"refseq:NP_056130.2|refseq:XP_005268461.1|ensembl:ENSG00000155506.19(gene)|ensembl:ENST00000518297.6(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0008190""(eukaryotic initiation factor 4E binding)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008494""(translation activator activity)|rcsb pdb:5C0V|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0031929""(TOR signaling)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045947""(negative regulation of translational initiation)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0072752""(cellular response to rapamycin)|go:""GO:1990928""(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|interpro:IPR045180|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3|rcsb pdb:7SOO|rcsb pdb:7SOP|rcsb pdb:7SOQ|rcsb pdb:7SOR|rcsb pdb:7SOS|rcsb pdb:7SOT|rcsb pdb:7SOU|rcsb pdb:7SOV|rcsb pdb:7SOW|rcsb pdb:8EY6|rcsb pdb:8EY7|rcsb pdb:8EY8|rcsb pdb:8G90|rcsb pdb:8G91|reactome:R-HSA-9705671|panther:PTHR22792(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4BbTj8554Gwm4rVypGL1Pva9DGE1392	rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606	intact-crc:0DB133F2F9537E55|rigid:Ub84SBReOowfBnT5mHhsfqMmDq8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UNZ5	uniprotkb:A0A6L8PXW6	intact:EBI-2830764|uniprotkb:B2R4J9|ensembl:ENSP00000465432.1	intact:EBI-2821561|uniprotkb:Q6KLX3|uniprotkb:Q6HSM8|uniprotkb:E9R3W7|uniprotkb:E9R3W8|uniprotkb:Q81L77|uniprotkb:A0A0F7RCR3	psi-mi:l10k_human(display_long)|uniprotkb:C19orf53(gene name)|psi-mi:C19orf53(display_short)|uniprotkb:HSPC023(orf name)	psi-mi:a0a6l8pxw6_bacan(display_long)|uniprotkb:sdhA(gene name)|psi-mi:sdhA(display_short)|uniprotkb:GBAA_4754(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830769|imex:IM-13779-3456	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_054766.1|ensembl:ENSG00000104979.9(gene)|ensembl:ENST00000588234.6(transcript)|interpro:IPR019034|mint:Q9UNZ5|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLC|rcsb pdb:8IDT|rcsb pdb:8IDY|rcsb pdb:8INE|rcsb pdb:8INF|dip:DIP-61980N|panther:PTHR16967(orthology-group)	"interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR011280(Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria)|interpro:IPR027477|go:""GO:0000104""(succinate dehydrogenase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0009055""(electron transfer activity)|go:""GO:0009061""(anaerobic respiration)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_000676736.1|interpro:IPR036188|interpro:IPR037099|interpro:IPR030664"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/20	rogid:Mdy8NfyuLddMoZlWKmEicxOuM109606	rogid:B95N82A5rfkh7/mfJ2A2PxqfcBM1392	intact-crc:D764297B69F56B7F|rigid:+OLydQh4IlxUUmhUjE+0NtEfRcM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P18627	uniprotkb:Q81VE1	intact:EBI-2830752|uniprotkb:A8K7T9|uniprotkb:Q7Z643|ensembl:ENSP00000203629.2	intact:EBI-2811760|uniprotkb:Q6I4E3|uniprotkb:Q6KY46	psi-mi:lag3_human(display_long)|uniprotkb:LAG3(gene name)|psi-mi:LAG3(display_short)|uniprotkb:FDC(gene name synonym)	psi-mi:ch60_bacan(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:BAS0253(locus name)|uniprotkb:BA_0267(locus name)|uniprotkb:GBAA_0267(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830783|imex:IM-13779-3457	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002277.4|ensembl:ENSG00000089692.9(gene)|ensembl:ENST00000203629.3(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002270""(plasmacytoid dendritic cell activation)|go:""GO:0003823""(antigen binding)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0042110""(T cell activation)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045590""(negative regulation of regulatory T cell differentiation)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0050776""(regulation of immune response)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR036179|rcsb pdb:7TZG|rcsb pdb:7TZH|rcsb pdb:7UM3|rcsb pdb:8SO3|rcsb pdb:8SR0|reactome:R-HSA-2132295|panther:PTHR11890(orthology-group)"	"interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016853""(isomerase activity)|go:""GO:0042026""(protein refolding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|refseq:WP_001030000.1|interpro:IPR027410|refseq:NP_842820.1|refseq:YP_026537.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LKgdGAeEExS57wqpGF8zyU2ODEw9606	rogid:rfS7W7PjZAE/lCghNeZHC3DI9IU1392	intact-crc:334FC158D7F9E23E|rigid:RQvmomXOFWx1WSazpJHiQTIDtT0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HB40	uniprotkb:P13010	intact:EBI-2812761|uniprotkb:Q6I3J5|uniprotkb:Q6KXA8|uniprotkb:E9R2F8|uniprotkb:E9R2F9|uniprotkb:A0A2P0H9V3|uniprotkb:Q81VA8	intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|ensembl:ENSP00000375977.2|ensembl:ENSP00000375978.3|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1	psi-mi:a0a6l7hb40_bacan(display_long)|uniprotkb:GBAA_0589(locus name)	"psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:""X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)""(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830797|imex:IM-13779-3461	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR001041(Ferredoxin)|interpro:IPR006478(Formate dehydrogenase, alpha subunit)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR019574|interpro:IPR050123|interpro:IPR027467|go:""GO:0003954""(NADH dehydrogenase activity)|go:""GO:0008863""(""formate dehydrogenase (NAD+) activity"")|go:""GO:0015942""(formate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_000840648.1|interpro:IPR036010|interpro:IPR041924"	"panther:PTHR12604(orthology-group)|ensembl:ENSG00000079246.16(gene)|ensembl:ENST00000392132.7(transcript)|ensembl:ENST00000392133.7(transcript)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000725""(recombinational repair)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000783""(nuclear telomere cap complex)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|refseq:NP_066964.1|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005958""(DNA-dependent protein kinase-DNA ligase 4 complex)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006303""(double-strand break repair via nonhomologous end joining)|go:""GO:0006310""(DNA recombination)|go:""GO:0006974""(DNA damage response)|go:""GO:0007004""(telomere maintenance via telomerase)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008094""(ATP-dependent activity, acting on DNA)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022008""(neurogenesis)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032040""(small-subunit processome)|go:""GO:0032204""(regulation of telomere maintenance)|go:""GO:0032991""(protein-containing complex)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034462""(small-subunit processome assembly)|go:""GO:0034511""(U3 snoRNA binding)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042162""(telomeric DNA binding)|go:""GO:0043564""(""Ku70:Ku80 complex"")|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045027""(DNA end binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0070198""(protein localization to chromosome, telomeric region)|go:""GO:0070418""(DNA-dependent protein kinase complex)|go:""GO:0070419""(nonhomologous end joining complex)|go:""GO:0071398""(cellular response to fatty acid)|go:""GO:0071425""(hematopoietic stem cell proliferation)|go:""GO:0071475""(cellular hyperosmotic salinity response)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071481""(cellular response to X-ray)|go:""GO:0090734""(site of DNA damage)|go:""GO:1904430""(negative regulation of t-circle formation)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7NFC|rcsb pdb:7NFE|rcsb pdb:7SGL|rcsb pdb:7SU3|rcsb pdb:7SUD|rcsb pdb:7Z6O|rcsb pdb:7Z87|rcsb pdb:7Z88|rcsb pdb:7ZT6|rcsb pdb:7ZVT|rcsb pdb:7ZWA|rcsb pdb:7ZYG|rcsb pdb:8AG4|rcsb pdb:8AG5|rcsb pdb:8ASC|rcsb pdb:8BH3|rcsb pdb:8BHV|rcsb pdb:8BHY|rcsb pdb:8BOT|rcsb pdb:8EZA|rcsb pdb:8EZB|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|dip:DIP-31379N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:QNDnbGYfnNxnQEMZtqgLWO6/cVs1392	rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606	intact-crc:12CD404CDB709F1F|rigid:R6bPqyKwLbj5G8I9Y0SoYIFnYJw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14618	uniprotkb:A0A384KSJ5	intact:EBI-353408|ensembl:ENSP00000334983.5|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-25600484|intact:EBI-2555890|uniprotkb:B4DUU6	intact:EBI-2817483|uniprotkb:Q6KTM4|uniprotkb:Q6HZN7|uniprotkb:E9R1A1|uniprotkb:E9R1A2|uniprotkb:Q81RG2|uniprotkb:A0A0F7RIX9	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:Threonine-protein kinase PKM2(gene name synonym)|uniprotkb:Tyrosine-protein kinase PKM2(gene name synonym)	psi-mi:a0a384ksj5_bacan(display_long)|uniprotkb:GBAA_2085(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830804|imex:IM-13779-3458	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|ensembl:ENSG00000067225.21(gene)|ensembl:ENST00000335181.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005929""(cilium)|go:""GO:0006096""(glycolytic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031982""(vesicle)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3SRH|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|rcsb pdb:7L21|rcsb pdb:8G2E|rcsb pdb:8HGF|rcsb pdb:8HMQ|rcsb pdb:8HMR|rcsb pdb:8HMS|rcsb pdb:8HMU|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70268|reactome:R-HSA-9861718|refseq:XP_005254502.1|refseq:NP_001193726.1|refseq:NP_001303247.1|dip:DIP-31273N|refseq:XP_016877802.1|panther:PTHR11817(orthology-group)"	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR000524(Bacterial regulatory protein GntR, HTH)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:WP_000366305.1|interpro:IPR051446|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rogid:rhVN9XT1HOWTYqxms87vlYh3G2o1392	intact-crc:95A88A6887B81519|rigid:4r5ojpvTRzpuP5gfHtmAYG98CUE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H8V8	uniprotkb:Q9NQT8	intact:EBI-2830843|uniprotkb:Q6KK40|uniprotkb:Q6HQS2|uniprotkb:E9QW09|uniprotkb:E9QW10|uniprotkb:Q81WY6|uniprotkb:A0A1J9WS90	intact:EBI-766408|uniprotkb:O75134|uniprotkb:Q9BYJ6|ensembl:ENSP00000427900.1|uniprotkb:F8VPJ2|uniprotkb:B4DGY5|uniprotkb:B5MC45|intact:EBI-11144050	psi-mi:a0a6l7h8v8_bacan(display_long)|uniprotkb:lldP2(gene name)|psi-mi:lldP2(display_short)|uniprotkb:GBAA_5464(locus name)	psi-mi:ki13b_human(display_long)|uniprotkb:Kinesin-like protein GAKIN(gene name synonym)|uniprotkb:KIF13B(gene name)|psi-mi:KIF13B(display_short)|uniprotkb:GAKIN(gene name synonym)|uniprotkb:KIAA0639(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830849|imex:IM-13779-3463	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003804(L-lactate permease)|refseq:WP_001099323.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015129""(lactate transmembrane transporter activity)|go:""GO:0015295""(""solute:proton symporter activity"")"	"refseq:NP_056069.2|ensembl:ENSG00000197892.13(gene)|ensembl:ENST00000524189.6(transcript)|go:""GO:0003777""(microtubule motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0006605""(protein targeting)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007165""(signal transduction)|go:""GO:0008017""(microtubule binding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030424""(axon)|go:""GO:0042110""(T cell activation)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0050770""(regulation of axonogenesis)|go:""GO:0071889""(14-3-3 protein binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR032405|interpro:IPR036859|interpro:IPR036961|rcsb pdb:2COW|rcsb pdb:3FM8|rcsb pdb:3GBJ|rcsb pdb:3MDB|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-34586N|panther:PTHR24115(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/22	rogid:wDvtAkVnhwt6n8xYqLyOTBlSnJ81392	rogid:dasf1WDho4yX7DWVOYfIpVNcRlE9606	intact-crc:A3EF9364DAC28550|rigid:JrVNDiMBXoQ8GsC50wWtaIt1R9s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14901	uniprotkb:A0A0F7REH3	intact:EBI-948266|uniprotkb:Q9EPF4|uniprotkb:B4DZE7|ensembl:ENSP00000307023.1	intact:EBI-2811064|uniprotkb:Q6KPV8|uniprotkb:E9R093|uniprotkb:Q81YE8	psi-mi:klf11_human(display_long)|uniprotkb:Transforming growth factor-beta-inducible early growth response protein 2(gene name synonym)|uniprotkb:KLF11(gene name)|psi-mi:KLF11(display_short)|uniprotkb:FKLF(gene name synonym)|uniprotkb:TIEG2(gene name synonym)	psi-mi:a0a0f7reh3_bacan(display_long)|uniprotkb:GBAA_3601(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830811|imex:IM-13779-3462	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005634""(nucleus)|ensembl:ENSG00000172059.11(gene)|ensembl:ENST00000305883.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016604""(nuclear body)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0046872""(metal ion binding)|go:""GO:1901653""(cellular response to peptide)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001171187.1|refseq:NP_001171189.1|refseq:NP_003588.1|efo:""Orphanet:552""|panther:PTHR23235(orthology-group)"	refseq:WP_001116379.1|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:C656ulgovyTl6k1M7CB1iXycek09606	rogid:kRV2TrznOHMKW2jOg5FKoFx9L+41392	intact-crc:40D831D542D2AC9F|rigid:YD6vOXxNUKrM+N8TMgsIewOnuUU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2U9	uniprotkb:Q81M98	intact:EBI-715326|uniprotkb:Q86TY9|uniprotkb:Q6IAF0|uniprotkb:B3KPF9|ensembl:ENSP00000298307.5	intact:EBI-2830821|uniprotkb:Q6KIZ6|uniprotkb:Q6HTQ1	psi-mi:kldc2_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated antigen 33(gene name synonym)|uniprotkb:Host cell factor homolog LCP(gene name synonym)|uniprotkb:Host cell factor-like protein 1(gene name synonym)|uniprotkb:KLHDC2(gene name)|psi-mi:KLHDC2(display_short)|uniprotkb:HCA33(gene name synonym)	psi-mi:argd_bacan(display_long)|uniprotkb:argD(gene name)|psi-mi:argD(display_short)|uniprotkb:BA_4352(locus name)|uniprotkb:GBAA_4352(locus name)|uniprotkb:BAS4037(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830818|imex:IM-13779-3464	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055130.1|ensembl:ENSG00000165516.11(gene)|ensembl:ENST00000298307.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR015915(Kelch-type beta propeller)|mint:Q9Y2U9|rcsb pdb:6DO3|rcsb pdb:6DO4|rcsb pdb:6DO5|rcsb pdb:8EBL|rcsb pdb:8EBM|rcsb pdb:8EBN|rcsb pdb:8PIF|rcsb pdb:8SGE|rcsb pdb:8SGF|rcsb pdb:8SH2|rcsb pdb:8UXS|panther:PTHR46228(orthology-group)"	"interpro:IPR004636(Acetylornithine and succinylornithine aminotransferase)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_000623333.1|go:""GO:0003992""(""N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"")|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0042802""(identical protein binding)|refseq:NP_846584.1|interpro:IPR050103|interpro:IPR049704"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YWJMGSX2MqvROFP492LhtVCjgrw9606	rogid:JjXJIA/jse17mR+1ZvpYO2ZzDCQ1392	intact-crc:8F5AA6F488F956F6|rigid:6UjRMIz7ukzvErGEGmyRhVcwO60	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HF87	uniprotkb:P33176	intact:EBI-2830831|uniprotkb:Q6KLE1|uniprotkb:Q6HS37|uniprotkb:E9R8V3|uniprotkb:E9R8V4|uniprotkb:Q81KN5|uniprotkb:A0A0F7R5J6	intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078.4	psi-mi:a0a6l7hf87_bacan(display_long)|uniprotkb:GBAA_4961(locus name)	psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830836|imex:IM-13779-3465	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004638(Drug resistance transporter EmrB/QacA subfamily)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|refseq:WP_001228009.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR036259"	"refseq:NP_004512.1|ensembl:ENSG00000170759.11(gene)|ensembl:ENST00000302418.5(transcript)|go:""GO:0003777""(microtubule motor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005871""(kinesin complex)|go:""GO:0005874""(microtubule)|go:""GO:0007018""(microtubule-based movement)|go:""GO:0007028""(cytoplasm organization)|go:""GO:0007411""(axon guidance)|go:""GO:0008017""(microtubule binding)|go:""GO:0008574""(plus-end-directed microtubule motor activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031982""(vesicle)|go:""GO:0032230""(positive regulation of synaptic transmission, GABAergic)|go:""GO:0032418""(lysosome localization)|go:""GO:0032839""(dendrite cytoplasm)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035253""(ciliary rootlet)|go:""GO:0035617""(stress granule disassembly)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042391""(regulation of membrane potential)|go:""GO:0042802""(identical protein binding)|go:""GO:0043268""(positive regulation of potassium ion transport)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048489""(synaptic vesicle transport)|go:""GO:0051642""(centrosome localization)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072383""(plus-end-directed vesicle transport along microtubule)|go:""GO:0098971""(anterograde dendritic transport of neurotransmitter receptor complex)|go:""GO:0098987""(regulation of modification of synapse structure, modulating synaptic transmission)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:0101004""(cytolytic granule membrane)|go:""GO:0160040""(mitocytosis)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1904115""(axon cytoplasm)|go:""GO:1990048""(anterograde neuronal dense core vesicle transport)|go:""GO:1990049""(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|rcsb pdb:7RIK|rcsb pdb:8IXA|rcsb pdb:8IXB|rcsb pdb:8IXD|rcsb pdb:8IXE|rcsb pdb:8IXF|rcsb pdb:8IXG|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-9725370|reactome:R-HSA-983189|dip:DIP-29244N|panther:PTHR24115(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:hByO02vVxRpnmjqUyDKqDeEx/I01392	rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606	intact-crc:2050680720942F96|rigid:K0YRLy+f3Yg3sOuutc/hkmuc0rI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H3F6	uniprotkb:Q81U22	intact:EBI-2505886|uniprotkb:Q53HN2|uniprotkb:Q59FV1|uniprotkb:Q6PL47|uniprotkb:Q96SU0|intact:EBI-2563423|ensembl:ENSP00000228495.6	intact:EBI-2814904|uniprotkb:Q6KW38|uniprotkb:Q6I2A7	psi-mi:bacd3_human(display_long)|uniprotkb:BTB/POZ domain-containing protein KCTD10(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 10(gene name synonym)|uniprotkb:KCTD10(gene name)|psi-mi:KCTD10(display_short)|uniprotkb:ULR061(gene name synonym)|uniprotkb:MSTP028(orf name)	psi-mi:cpfc1_bacan(display_long)|uniprotkb:cpfC1(gene name)|psi-mi:cpfC1(display_short)|uniprotkb:hemH-1(gene name synonym)|uniprotkb:hemH1(gene name synonym)|uniprotkb:BAS1000(locus name)|uniprotkb:BA_1071(locus name)|uniprotkb:GBAA_1071(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830877|imex:IM-13779-3468	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_114160.1|ensembl:ENSG00000110906.13(gene)|ensembl:ENST00000228495.11(transcript)|go:""GO:0005112""(Notch binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031463""(Cul3-RING ubiquitin ligase complex)|go:""GO:0035024""(negative regulation of Rho protein signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0051260""(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR045068|mint:Q9H3F6|rcsb pdb:5FTA|refseq:NP_001304324.1|refseq:NP_001304328.1|panther:PTHR11145(orthology-group)"	"interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|rcsb pdb:2C8J|interpro:IPR033644|interpro:IPR033659|go:""GO:0004325""(ferrochelatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:NP_843565.1|refseq:YP_027273.1|refseq:WP_000726793.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ol+Pl17F/3aoKl1CD+edgT9KweI9606	rogid:VgwkMIvazgaeCD8Rq+iY6Sn7gk01392	intact-crc:5C9BDDC0475D407A|rigid:r1vNWY2lrFrnBfoeNvEZLhFcqNk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2U9	uniprotkb:Q9RMZ3	intact:EBI-715326|uniprotkb:Q86TY9|uniprotkb:Q6IAF0|uniprotkb:B3KPF9|ensembl:ENSP00000298307.5	intact:EBI-2820320|uniprotkb:A0A6L7HBM1	psi-mi:kldc2_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated antigen 33(gene name synonym)|uniprotkb:Host cell factor homolog LCP(gene name synonym)|uniprotkb:Host cell factor-like protein 1(gene name synonym)|uniprotkb:KLHDC2(gene name)|psi-mi:KLHDC2(display_short)|uniprotkb:HCA33(gene name synonym)	psi-mi:q9rmz3_bacan(display_long)|uniprotkb:capR(gene name)|psi-mi:capR(display_short)|uniprotkb:GBAA_pXO2_0040(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830856|imex:IM-13779-3466	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055130.1|ensembl:ENSG00000165516.11(gene)|ensembl:ENST00000298307.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016604""(nuclear body)|go:""GO:0031462""(Cul2-RING ubiquitin ligase complex)|go:""GO:0031965""(nuclear membrane)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0140627""(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:""GO:1990756""(ubiquitin-like ligase-substrate adaptor activity)|interpro:IPR015915(Kelch-type beta propeller)|mint:Q9Y2U9|rcsb pdb:6DO3|rcsb pdb:6DO4|rcsb pdb:6DO5|rcsb pdb:8EBL|rcsb pdb:8EBM|rcsb pdb:8EBN|rcsb pdb:8PIF|rcsb pdb:8SGE|rcsb pdb:8SGF|rcsb pdb:8SH2|rcsb pdb:8UXS|panther:PTHR46228(orthology-group)"	refseq:WP_000400406.1|refseq:NP_053194.1|interpro:IPR025669|interpro:IPR027417|interpro:IPR050678	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YWJMGSX2MqvROFP492LhtVCjgrw9606	rogid:aAYoIttBfJ51/60pEmBMu1KAreU1392	intact-crc:9EB34DFAFBEC767E|rigid:D6nyj4unWM8LIx8ZluM+bZf7Z9s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17612	uniprotkb:Q81VT8	intact:EBI-476586|ensembl:ENSP00000309591.3|ensembl:ENSP00000499940.1|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9	intact:EBI-2811891|uniprotkb:Q6I4U2	psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym)	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830884|imex:IM-13779-3470	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000072062.16(gene)|ensembl:ENSG00000288516.1(gene)|ensembl:ENST00000308677.9(transcript)|ensembl:ENST00000673550.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001707""(mesoderm formation)|go:""GO:0001843""(neural tube closure)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0003091""(renal water homeostasis)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004691""(cAMP-dependent protein kinase activity)|go:""GO:0004712""(protein serine/threonine/tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0006397""(mRNA processing)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0007165""(signal transduction)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016607""(nuclear speck)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030145""(manganese ion binding)|go:""GO:0031588""(nucleotide-activated protein kinase complex)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|go:""GO:0034380""(high-density lipoprotein particle assembly)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034704""(calcium channel complex)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0036126""(sperm flagellum)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0045722""(positive regulation of gluconeogenesis)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0048240""(sperm capacitation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0055117""(regulation of cardiac muscle contraction)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070417""(cellular response to cold)|go:""GO:0070613""(regulation of protein processing)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071374""(cellular response to parathyroid hormone stimulus)|go:""GO:0071377""(cellular response to glucagon stimulus)|go:""GO:0071872""(cellular response to epinephrine stimulus)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097546""(ciliary base)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099103""(channel activator activity)|go:""GO:0099170""(postsynaptic modulation of chemical synaptic transmission)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0141156""(cAMP/PKA signal transduction)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904539""(negative regulation of glycolytic process through fructose-6-phosphate)|go:""GO:1990044""(protein localization to lipid droplet)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P17612|rcsb pdb:2GU8|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:7Y1G|rcsb pdb:8FE2|rcsb pdb:8FE5|rcsb pdb:8FEC|rcsb pdb:8X5L|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-8963896|reactome:R-HSA-9010642|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634597|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9837999|reactome:R-HSA-9856530|refseq:NP_001291278.1|refseq:NP_002721.1|refseq:NP_997401.1|dip:DIP-33878N|efo:""Orphanet:289""|efo:""Orphanet:401920""|panther:PTHR24353(orthology-group)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	intact-crc:1E84C4DD338A4420|rigid:xsc+8yJ1JZRlRbifgpjbqM8IMzE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N5I3	uniprotkb:Q6KNA9	intact:EBI-745755|uniprotkb:Q0P6D0|uniprotkb:Q8IU75|uniprotkb:Q8N3Q9|uniprotkb:A2A2X9|ensembl:ENSP00000324191.1	intact:EBI-2812936|uniprotkb:Q6HU26|uniprotkb:Q81MM9	psi-mi:kcnrg_human(display_long)|uniprotkb:Protein CLLD4(gene name synonym)|uniprotkb:KCNRG(gene name)|psi-mi:KCNRG(display_short)|uniprotkb:CLLD4(gene name synonym)	psi-mi:mete_bacan(display_long)|uniprotkb:metE(gene name)|psi-mi:metE(display_short)|uniprotkb:Cobalamin-independent methionine synthase(gene name synonym)|uniprotkb:Methionine synthase, vitamin-B12 independent isozyme(gene name synonym)|uniprotkb:BA_4218(locus name)|uniprotkb:GBAA_4218(locus name)|uniprotkb:BAS3912(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830870|imex:IM-13779-3467	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_775876.1|refseq:NP_955751.1|ensembl:ENSG00000198553.9(gene)|ensembl:ENST00000312942.2(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0042802""(identical protein binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:1902260""(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q8N5I3|panther:PTHR14499(orthology-group)"	"refseq:WP_001007635.1|interpro:IPR013215(""Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal"")|interpro:IPR006276(5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase)|interpro:IPR002629(Methionine synthase, vitamin-B12 independent)|go:""GO:0003871""(5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0032259""(methylation)|interpro:IPR038071|refseq:NP_846453.1|refseq:YP_030162.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Zl81okdqtLzwJC8HsHA+g9n7JXs9606	rogid:zrEJnY1x7+9Q1u7iaM9JmIvFVAQ1392	intact-crc:A56002EE8D62D15C|rigid:Pl+bRC+PhvmqgijJc6+0GE6qVdw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P1I7	uniprotkb:Q8N5I3	intact:EBI-2809746|uniprotkb:Q6KXV0|uniprotkb:Q6I440|uniprotkb:E9RCC7|uniprotkb:E9RCC8|uniprotkb:A0A2P0H989|uniprotkb:Q81Z98	intact:EBI-745755|uniprotkb:Q0P6D0|uniprotkb:Q8IU75|uniprotkb:Q8N3Q9|uniprotkb:A2A2X9|ensembl:ENSP00000324191.1	psi-mi:a0a6l8p1i7_bacan(display_long)|uniprotkb:GBAA_0374(locus name)	psi-mi:kcnrg_human(display_long)|uniprotkb:Protein CLLD4(gene name synonym)|uniprotkb:KCNRG(gene name)|psi-mi:KCNRG(display_short)|uniprotkb:CLLD4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830863|imex:IM-13779-3469	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017501(Phage infection protein, YhgE,  C-terminal)|interpro:IPR017500(Phage infection protein, YhgE,  N-terminal)|interpro:IPR051328|go:""GO:0016020""(membrane)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR013525(ABC-2 type transporter)|refseq:WP_000810134.1"	"refseq:NP_775876.1|refseq:NP_955751.1|ensembl:ENSG00000198553.9(gene)|ensembl:ENST00000312942.2(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0042802""(identical protein binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:1902260""(negative regulation of delayed rectifier potassium channel activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q8N5I3|panther:PTHR14499(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Km4jDuu44pVTrI8b6www/dkgkrY1392	rogid:Zl81okdqtLzwJC8HsHA+g9n7JXs9606	intact-crc:BF4F4C2DC1FDCA5D|rigid:Dq9GkoyOjDy01SsGWiVY094kZBM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13861	uniprotkb:Q81XR1	intact:EBI-2556122|uniprotkb:Q16823|intact:EBI-6116682|uniprotkb:Q9BUB1|intact:EBI-10961724|ensembl:ENSP00000265563.8|ensembl:ENSP00000394041.1|ensembl:ENSP00000516459.1	intact:EBI-2829582|uniprotkb:Q6KKV5|uniprotkb:Q6HRI8	psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short)	psi-mi:y5172_bacan(display_long)|uniprotkb:BA_5172(locus name)|uniprotkb:GBAA_5172(locus name)|uniprotkb:BAS4807(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830912|imex:IM-13779-3472	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-552N|refseq:XP_011532244.1|refseq:NP_004148.1|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:XP_016862304.1|ensembl:ENSG00000114302.17(gene)|ensembl:ENST00000265563.13(transcript)|ensembl:ENST00000454963.5(transcript)|ensembl:ENST00000706574.1(transcript)|go:""GO:0004862""(cAMP-dependent protein kinase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0008603""(cAMP-dependent protein kinase regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030552""(cAMP binding)|go:""GO:0031588""(nucleotide-activated protein kinase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097546""(ciliary base)|go:""GO:0141162""(negative regulation of cAMP/PKA signal transduction)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR050503|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|rcsb pdb:8S8O|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9856530|panther:PTHR11635(orthology-group)"	interpro:IPR022916|interpro:IPR009910(Protein of unknown function DUF1450)|refseq:WP_000595026.1|refseq:NP_847355.1|refseq:YP_031050.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606	rogid:jjkEEv3edo7Wp9aU9INQn6yhQik1392	intact-crc:98BC086B6182C940|rigid:j0seea/NLq+wCF0PRcpqIE4XzUw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81UI7	uniprotkb:P01834	intact:EBI-2815395|uniprotkb:Q6KWJ7|uniprotkb:Q6I2R6	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:seca2_bacan(display_long)|uniprotkb:secA2(gene name)|psi-mi:secA2(display_short)|uniprotkb:BA_0882(locus name)|uniprotkb:GBAA_0882(locus name)|uniprotkb:BAS0838(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830931|imex:IM-13779-3476	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR044722|interpro:IPR030908|interpro:IPR000185(SecA protein)|interpro:IPR020937|interpro:IPR011115(SecA DEAD-like)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0017038""(protein import)|go:""GO:0031522""(cell envelope Sec protein transport complex)|go:""GO:0043952""(protein transport by the Sec complex)|go:""GO:0065002""(intracellular protein transmembrane transport)|refseq:WP_000935179.1|interpro:IPR036266|interpro:IPR036670|refseq:NP_843394.1|refseq:YP_027114.1"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3++Awu9K48Y1hL1D9TCzw1CepFs1392	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:20016C108B796F48|rigid:AyUjdJf22VL+QszIv5qkttE0h5E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H9A7	uniprotkb:P13861	intact:EBI-2816086|uniprotkb:Q6KKA3|uniprotkb:Q6HQY4|uniprotkb:E9QWA3|uniprotkb:E9QWA4|uniprotkb:Q81X48|uniprotkb:A0A1J9WVL8	intact:EBI-2556122|uniprotkb:Q16823|intact:EBI-6116682|uniprotkb:Q9BUB1|intact:EBI-10961724|ensembl:ENSP00000265563.8|ensembl:ENSP00000394041.1|ensembl:ENSP00000516459.1	psi-mi:a0a6l7h9a7_bacan(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:GBAA_5395(locus name)	psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830898|imex:IM-13779-3471	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000045565.1|interpro:IPR041102|interpro:IPR041552|interpro:IPR013815(ATP-grasp fold, subdomain 1)"	"dip:DIP-552N|refseq:XP_011532244.1|refseq:NP_004148.1|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:XP_016862304.1|ensembl:ENSG00000114302.17(gene)|ensembl:ENST00000265563.13(transcript)|ensembl:ENST00000454963.5(transcript)|ensembl:ENST00000706574.1(transcript)|go:""GO:0004862""(cAMP-dependent protein kinase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0008603""(cAMP-dependent protein kinase regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030552""(cAMP binding)|go:""GO:0031588""(nucleotide-activated protein kinase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097546""(ciliary base)|go:""GO:0141162""(negative regulation of cAMP/PKA signal transduction)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR050503|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|rcsb pdb:8S8O|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9856530|panther:PTHR11635(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:8J+yjOUWiDCOsqLZUtYwrwWzv241392	rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606	intact-crc:9D36357A81CDE3DB|rigid:N/hH4BsrrsawyhxSMjoszyIKac4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HBY9	uniprotkb:P13861	intact:EBI-2830919|uniprotkb:Q6KXA3|uniprotkb:Q6I3I9|uniprotkb:E9QZ28|uniprotkb:E9QZ29|uniprotkb:Q81VA3|uniprotkb:A0A0F7RHE4	intact:EBI-2556122|uniprotkb:Q16823|intact:EBI-6116682|uniprotkb:Q9BUB1|intact:EBI-10961724|ensembl:ENSP00000265563.8|ensembl:ENSP00000394041.1|ensembl:ENSP00000516459.1	psi-mi:a0a6l7hby9_bacan(display_long)|uniprotkb:GBAA_0595(locus name)	psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830924|imex:IM-13779-3473	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR027256|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR023299|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR018303|interpro:IPR023214|interpro:IPR017969|interpro:IPR006121(Heavy metal transport/detoxification protein)|refseq:WP_000796585.1|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015086""(cadmium ion transmembrane transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019829""(ATPase-coupled monoatomic cation transmembrane transporter activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR023298|interpro:IPR036163|interpro:IPR036412|interpro:IPR044492|interpro:IPR051014"	"dip:DIP-552N|refseq:XP_011532244.1|refseq:NP_004148.1|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:XP_016862304.1|ensembl:ENSG00000114302.17(gene)|ensembl:ENST00000265563.13(transcript)|ensembl:ENST00000454963.5(transcript)|ensembl:ENST00000706574.1(transcript)|go:""GO:0004862""(cAMP-dependent protein kinase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0008603""(cAMP-dependent protein kinase regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030552""(cAMP binding)|go:""GO:0031588""(nucleotide-activated protein kinase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097546""(ciliary base)|go:""GO:0141162""(negative regulation of cAMP/PKA signal transduction)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR050503|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|rcsb pdb:8S8O|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9856530|panther:PTHR11635(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:m4O/zjch7BrSPwbHw8v3PzKrTbc1392	rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606	intact-crc:90D4237294032164|rigid:Ovx4/GLd616zctLW4CSmejjRtbc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7RE19	uniprotkb:P13861	intact:EBI-2809783|uniprotkb:Q6KPM6|uniprotkb:Q6HVF7|uniprotkb:E9QS28|uniprotkb:E9QS29|uniprotkb:Q81Y62	intact:EBI-2556122|uniprotkb:Q16823|intact:EBI-6116682|uniprotkb:Q9BUB1|intact:EBI-10961724|ensembl:ENSP00000265563.8|ensembl:ENSP00000394041.1|ensembl:ENSP00000516459.1	psi-mi:a0a0f7re19_bacan(display_long)|uniprotkb:GBAA_3695(locus name)	psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830891|imex:IM-13779-3474	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001119(S-layer homology region)|interpro:IPR051465|go:""GO:0030115""(S-layer)|interpro:IPR032247"	"dip:DIP-552N|refseq:XP_011532244.1|refseq:NP_004148.1|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:XP_016862304.1|ensembl:ENSG00000114302.17(gene)|ensembl:ENST00000265563.13(transcript)|ensembl:ENST00000454963.5(transcript)|ensembl:ENST00000706574.1(transcript)|go:""GO:0004862""(cAMP-dependent protein kinase inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0008603""(cAMP-dependent protein kinase regulator activity)|go:""GO:0016020""(membrane)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030552""(cAMP binding)|go:""GO:0031588""(nucleotide-activated protein kinase complex)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034236""(protein kinase A catalytic subunit binding)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097546""(ciliary base)|go:""GO:0141162""(negative regulation of cAMP/PKA signal transduction)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR050503|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|rcsb pdb:8S8O|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9856530|panther:PTHR11635(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:RZeq/OQN8n8nnEe280+/uO/FFX01392	rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606	intact-crc:436FC9C4D973C3A9|rigid:rZfdk3VT9siNstWOQgckrSy01rY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17612	uniprotkb:A0A6L7H2Q9	intact:EBI-476586|ensembl:ENSP00000309591.3|ensembl:ENSP00000499940.1|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9	intact:EBI-2810400|uniprotkb:Q6KTQ9|uniprotkb:Q6HZS4|uniprotkb:E9RAZ3|uniprotkb:E9RAZ4|uniprotkb:Q81RJ7|uniprotkb:A0A0F7RD30	psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym)	psi-mi:a0a6l7h2q9_bacan(display_long)|uniprotkb:GBAA_2047(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830905|imex:IM-13779-3475	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000072062.16(gene)|ensembl:ENSG00000288516.1(gene)|ensembl:ENST00000308677.9(transcript)|ensembl:ENST00000673550.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001707""(mesoderm formation)|go:""GO:0001843""(neural tube closure)|go:""GO:0002027""(regulation of heart rate)|go:""GO:0003091""(renal water homeostasis)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004691""(cAMP-dependent protein kinase activity)|go:""GO:0004712""(protein serine/threonine/tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005952""(cAMP-dependent protein kinase complex)|go:""GO:0006397""(mRNA processing)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0007165""(signal transduction)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0007193""(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:""GO:0010881""(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016607""(nuclear speck)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030145""(manganese ion binding)|go:""GO:0031588""(nucleotide-activated protein kinase complex)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|go:""GO:0034380""(high-density lipoprotein particle assembly)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034704""(calcium channel complex)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0036126""(sperm flagellum)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045667""(regulation of osteoblast differentiation)|go:""GO:0045722""(positive regulation of gluconeogenesis)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0046827""(positive regulation of protein export from nucleus)|go:""GO:0048240""(sperm capacitation)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0055117""(regulation of cardiac muscle contraction)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070417""(cellular response to cold)|go:""GO:0070613""(regulation of protein processing)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071374""(cellular response to parathyroid hormone stimulus)|go:""GO:0071377""(cellular response to glucagon stimulus)|go:""GO:0071872""(cellular response to epinephrine stimulus)|go:""GO:0086064""(cell communication by electrical coupling involved in cardiac conduction)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097546""(ciliary base)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099103""(channel activator activity)|go:""GO:0099170""(postsynaptic modulation of chemical synaptic transmission)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0141156""(cAMP/PKA signal transduction)|go:""GO:1903779""(regulation of cardiac conduction)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904539""(negative regulation of glycolytic process through fructose-6-phosphate)|go:""GO:1990044""(protein localization to lipid droplet)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P17612|rcsb pdb:2GU8|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:3MVJ|rcsb pdb:3NX8|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:7Y1G|rcsb pdb:8FE2|rcsb pdb:8FE5|rcsb pdb:8FEC|rcsb pdb:8X5L|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-8963896|reactome:R-HSA-9010642|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634597|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9837999|reactome:R-HSA-9856530|refseq:NP_001291278.1|refseq:NP_002721.1|refseq:NP_997401.1|dip:DIP-33878N|efo:""Orphanet:289""|efo:""Orphanet:401920""|panther:PTHR24353(orthology-group)"	interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:WP_000216920.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606	rogid:H+yb15aOHMi9sIfuMqerdtx927Y1392	intact-crc:0C3338E9F10ABE71|rigid:xXerbHAp03GmM/JqZtEEt7iyQ3o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NZ90	uniprotkb:P01834	intact:EBI-2822559|uniprotkb:Q6KRW3|uniprotkb:Q6HXU2|uniprotkb:E9QQP0|uniprotkb:E9QQP1|uniprotkb:Q81PM7|uniprotkb:A0A0F7RHX1	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:a0a6l8nz90_bacan(display_long)|uniprotkb:acoB(gene name)|psi-mi:acoB(display_short)|uniprotkb:GBAA_2775(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830966|imex:IM-13779-3479	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033248|interpro:IPR029061|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|go:""GO:0016491""(oxidoreductase activity)|refseq:WP_000198888.1"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AJmoQea5oxqVcU8nkiE5DDiFS8w1392	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:B99899DB25F1DBF7|rigid:LtVHVpVBvtEbFNTaGBioaqJKOVw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:P01834	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830959|imex:IM-13779-3478	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:97123382C11B9E52|rigid:VqQPd8iWhGHVIiDXscQ/FPeOjsY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:Q9X334	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2819898|uniprotkb:A0A0F7RIK4	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:q9x334_bacan(display_long)|uniprotkb:GBAA_pXO1_0090(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830938|imex:IM-13779-3481	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"refseq:NP_052760.1|go:""GO:0016020""(membrane)|refseq:WP_000879954.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:U6gDbHhBlQouY0JnJALgbwVgVsk1392	intact-crc:02B5B074FA8CD60F|rigid:p5b2M9Kb52okNIO0OuTo09sv/KE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PSZ0	uniprotkb:P01834	intact:EBI-2820328|uniprotkb:Q6KVK0|uniprotkb:Q6I1Q8|uniprotkb:E9QX09|uniprotkb:E9QX10|uniprotkb:Q81TH5|uniprotkb:A0A0F7RLZ4	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:a0a6l8psz0_bacan(display_long)|uniprotkb:GBAA_1300(locus name)|uniprotkb:potD(gene name)|psi-mi:potD(display_short)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830952|imex:IM-13779-3480	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|go:""GO:0015846""(polyamine transport)|go:""GO:0019808""(polyamine binding)|go:""GO:0042597""(periplasmic space)|refseq:WP_000779003.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:N5S8foUwPHnwNk6wOSAsTNvMzIc1392	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:9D16D5A5661DDA4F|rigid:vAnOChJ/dWbcrgsHK1WuRWnx9JA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PQR4	uniprotkb:P01834	intact:EBI-2811635|uniprotkb:Q6I443|uniprotkb:Q6KXV3|uniprotkb:E9R6Y1|uniprotkb:E9R6Y2|uniprotkb:Q81ZA1|uniprotkb:A0A2B6CBL2	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:a0a6l8pqr4_bacan(display_long)|uniprotkb:GBAA_0371(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830945|imex:IM-13779-3477	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR032091|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|go:""GO:0004556""(alpha-amylase activity)|go:""GO:0009313""(oligosaccharide catabolic process)|refseq:WP_001044735.1|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR045857"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Dtzg5gPp1dA60+U3XNlVLtv3qQ01392	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:607BEF580A413BC5|rigid:9j2wIFUt4r4fqcmw1mPLf88VnXY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:Q81LC5	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2819855|uniprotkb:Q6KM21|uniprotkb:Q6HSS8	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:hem1_bacan(display_long)|uniprotkb:hemA(gene name)|psi-mi:hemA(display_short)|uniprotkb:BA_4698(locus name)|uniprotkb:GBAA_4698(locus name)|uniprotkb:BAS4363(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831006|imex:IM-13779-3486	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"interpro:IPR000343(Tetrapyrrole biosynthesis, glutamyl-tRNA reductase)|interpro:IPR015896(Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, C-terminal)|interpro:IPR015895(Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal)|interpro:IPR018214|interpro:IPR006151(Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0008883""(glutamyl-tRNA reductase activity)|go:""GO:0050661""(NADP binding)|refseq:WP_000547860.1|interpro:IPR036291|interpro:IPR036343|interpro:IPR036453|refseq:NP_846911.1|refseq:YP_030610.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:/YiJle2dPlU5aBiRykxSArqFTjg1392	intact-crc:188A85108BC2C8CB|rigid:DG4oCBLcX2FX3c6Kldp2NhFZufc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86Y46	uniprotkb:Q81JX0	intact:EBI-2830994|uniprotkb:Q32MB2|ensembl:ENSP00000307014.3	intact:EBI-2821962|uniprotkb:Q6HQH0|uniprotkb:Q6KJU4	psi-mi:k2c73_human(display_long)|uniprotkb:KRT73(gene name)|psi-mi:KRT73(display_short)|uniprotkb:K6IRS3(gene name synonym)|uniprotkb:KB36(gene name synonym)|uniprotkb:KRT6IRS3(gene name synonym)|uniprotkb:Cytokeratin-73(gene name synonym)|uniprotkb:Keratin-73(gene name synonym)|uniprotkb:Type II inner root sheath-specific keratin-K6irs3(gene name synonym)|uniprotkb:Type-II keratin Kb36(gene name synonym)	psi-mi:kith_bacan(display_long)|uniprotkb:tdk(gene name)|psi-mi:tdk(display_short)|uniprotkb:BA_5573(locus name)|uniprotkb:GBAA_5573(locus name)|uniprotkb:BAS5179(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830999|imex:IM-13779-3484	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_778238.1|ensembl:ENSG00000186049.8(gene)|ensembl:ENST00000305748.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0030280""(structural constituent of skin epidermis)|go:""GO:0031424""(keratinization)|go:""GO:0045095""(keratin filament)|go:""GO:0045109""(intermediate filament organization)|go:""GO:0070062""(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:Q86Y46|reactome:R-HSA-6805567|reactome:R-HSA-6809371|panther:PTHR45616(orthology-group)"	"interpro:IPR001267(Thymidine kinase)|interpro:IPR020633|rcsb pdb:2J9R|interpro:IPR027417|go:""GO:0004797""(thymidine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0046104""(thymidine metabolic process)|go:""GO:0071897""(DNA biosynthetic process)|refseq:WP_000280866.1|refseq:NP_847730.1|refseq:YP_031418.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6kG8MsN4Kkiajs527gKWDg1zRpY9606	rogid:fC2DrvjGW7q89ZmsAOf5lt7m8NY1392	intact-crc:75333C19AD1806DB|rigid:zBbsYWp+3nFp6t1dHb6hW/LW/zg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HJT4	uniprotkb:P01834	intact:EBI-2809861|uniprotkb:Q6KQT1|uniprotkb:Q6HWN8|uniprotkb:E9R665|uniprotkb:E9R666|uniprotkb:A0A2P0HGD7|uniprotkb:Q81NH4	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:a0a6l7hjt4_bacan(display_long)|uniprotkb:cypD(gene name)|psi-mi:cypD(display_short)|uniprotkb:GBAA_3221(locus name)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830980|imex:IM-13779-3485	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023206|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR017927|interpro:IPR001094(Flavodoxin-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001433(""Oxidoreductase FAD/NAD(P)-binding"")|interpro:IPR017938|interpro:IPR029039|go:""GO:0003958""(NADPH-hemoprotein reductase activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0010181""(FMN binding)|go:""GO:0020037""(heme binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0070330""(aromatase activity)|refseq:WP_000359079.1|interpro:IPR023173|interpro:IPR036396|interpro:IPR039261"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zhoaOvUxUjv19qj1am2VKlovHG81392	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	intact-crc:AE735C90CCF84FBC|rigid:35VL39Lo0MPUHSKg8ZnE56U/Iw8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:A0A6H3AJ02	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2827404|uniprotkb:Q6KRV3|uniprotkb:Q6HXT2|uniprotkb:E9QY69|uniprotkb:E9QY70|uniprotkb:Q81PL6|uniprotkb:A0A1Q4LZ40	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:a0a6h3aj02_bacan(display_long)|uniprotkb:proV2(gene name)|psi-mi:proV2(display_short)|uniprotkb:GBAA_2786(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830973|imex:IM-13779-3482	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR005892(Glycine betaine/L-proline transport ATP-binding subunit)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0031460""(glycine betaine transport)|refseq:WP_000370609.1|interpro:IPR051921|interpro:IPR046342"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:JP/dDDY8zHvUtq6CRi/cTd9BTpk1392	intact-crc:B42AA1498B0B1B1E|rigid:Vlh7XmwaVn34FYxmBJFF+oi6RZE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01834	uniprotkb:Q81S14	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	intact:EBI-2811794|uniprotkb:Q6I094|uniprotkb:Q6KU68	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:mtad_bacan(display_long)|uniprotkb:mtaD(gene name)|psi-mi:mtaD(display_short)|uniprotkb:BA_1865(locus name)|uniprotkb:GBAA_1865(locus name)|uniprotkb:BAS1729(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2830987|imex:IM-13779-3483	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:183675""|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0071738""(IgD immunoglobulin complex)|go:""GO:0071742""(IgE immunoglobulin complex)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071753""(IgM immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01834|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1CLY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1GAF|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:3BKY|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1N0X|rcsb pdb:1UCB|rcsb pdb:2NY7|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2RFX|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3IU3|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:3RU8|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:4D3C|rcsb pdb:4D9R|rcsb pdb:4HIX|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5C7K|rcsb pdb:5ESV|rcsb pdb:5ESZ|rcsb pdb:5EWI|rcsb pdb:5VEB|rcsb pdb:5VIY|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:6OGE|rcsb pdb:6OKP|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7XQ8|rcsb pdb:8C1C|rcsb pdb:8DAO|rcsb pdb:8DBZ|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9679191|reactome:R-HSA-977606|reactome:R-HSA-983695|panther:PTHR23266(orthology-group)"	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR023512|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR050287|go:""GO:0046872""(metal ion binding)|go:""GO:0050270""(S-adenosylhomocysteine deaminase activity)|go:""GO:0090614""(5'-methylthioadenosine deaminase activity)|interpro:IPR032466|refseq:NP_844282.1|refseq:YP_027994.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rogid:TDYnZJrYplZEtZNuGj+DQVH3gl81392	intact-crc:E1164A108B8C78DB|rigid:Z9cyEfRMJ0gTECtD+D2CKMgy5CQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q68DE3	uniprotkb:A0A6L7HRA4	intact:EBI-2831020|uniprotkb:Q9H8T4|uniprotkb:Q8IVF3|uniprotkb:Q7Z3L9|ensembl:ENSP00000320794.4|ensembl:ENSP00000420721.1	intact:EBI-2813473|uniprotkb:Q6HQQ3|uniprotkb:Q6KK24|uniprotkb:E9R8B1|uniprotkb:E9R8B2|uniprotkb:Q81K50|uniprotkb:A0A0F7R5G0	psi-mi:usf3_human(display_long)|uniprotkb:KIAA2018(gene name synonym)|uniprotkb:Upstream transcription factor 3(gene name synonym)|uniprotkb:USF3(gene name)|psi-mi:USF3(display_short)	psi-mi:a0a6l7hra4_bacan(display_long)|uniprotkb:GBAA_5487(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831029|imex:IM-13779-3487	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:201""|ensembl:ENSG00000176542.10(gene)|ensembl:ENST00000316407.9(transcript)|ensembl:ENST00000478658.1(transcript)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0010719""(negative regulation of epithelial to mesenchymal transition)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046983""(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR048064|interpro:IPR053252|refseq:NP_001009899.3|refseq:XP_016861360.1|panther:PTHR46970(orthology-group)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022138|interpro:IPR000330(SNF2-related)|interpro:IPR038718|interpro:IPR027417|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)|refseq:WP_000610083.1|interpro:IPR049730"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:blGiYH2RxFY5yYa7rj2FefTu98M9606	rogid:Cs/6ntowxGUivXGkMJr5JhYRMVk1392	intact-crc:5671078F421B8D34|rigid:zrCt/dEhZzIiyHcAfl2GFCtDwrM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HIZ6	uniprotkb:Q8N163	intact:EBI-2814832|uniprotkb:Q6KTQ4|uniprotkb:Q6HZR9|uniprotkb:E9R314|uniprotkb:E9R315|uniprotkb:Q81RJ2|uniprotkb:A0A1J9VS64	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|uniprotkb:B2RB79|uniprotkb:D3DSR6|ensembl:ENSP00000310670.4|ensembl:ENSP00000373930.3	psi-mi:a0a6l7hiz6_bacan(display_long)|uniprotkb:GBAA_2052(locus name)	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831036|imex:IM-13779-3489	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015402(Protein of unknown function DUF1980)|interpro:IPR052955|go:""GO:0016020""(membrane)|refseq:WP_000488047.1|interpro:IPR048447|interpro:IPR048493"	"refseq:NP_066997.3|ensembl:ENSG00000158941.17(gene)|ensembl:ENST00000308511.9(transcript)|ensembl:ENST00000389279.7(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005819""(spindle)|go:""GO:0006397""(mRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0008380""(RNA splicing)|go:""GO:0009411""(response to UV)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032784""(regulation of DNA-templated transcription elongation)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0044609""(DBIRD complex)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048511""(rhythmic process)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090311""(regulation of protein deacetylation)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:2000003""(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR045353|interpro:IPR045354|mint:Q8N163|rcsb pdb:8EZ6|reactome:R-HSA-3371453|dip:DIP-38122N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:V2N/c+sGid0sD9gvWn/yBhUT3DI1392	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	intact-crc:F6BC49CC8812F0BA|rigid:fviNQFZhW3PbVhrku2bq0hlRmdI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C0F1	uniprotkb:A0A6L7H5N1	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519.4|ensembl:ENSP00000380009.3|ensembl:ENSP00000423153.1	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831050|imex:IM-13779-3491	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035247.1|refseq:NP_001138786.1|ensembl:ENSG00000164118.13(gene)|ensembl:ENST00000296519.6(transcript)|ensembl:ENST00000396791.7(transcript)|ensembl:ENST00000503780.6(transcript)|go:""GO:0000922""(spindle pole)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007099""(centriole replication)|go:""GO:0008017""(microtubule binding)|go:""GO:0010457""(centriole-centriole cohesion)|go:""GO:0030496""(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|rcsb pdb:7PT5|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|panther:PTHR31477(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:9CC7E1461B58D9B5|rigid:MSSPExXVI6exG9bvoaM80I8EcNQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:Q5HYC2	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-948754|intact:EBI-28977075|uniprotkb:A8MTP2|uniprotkb:Q4VXA2|uniprotkb:Q8IVE5|uniprotkb:B9EGW7|ensembl:ENSP00000382815.3	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:brd10_human(display_long)|uniprotkb:BRD10(gene name)|psi-mi:BRD10(display_short)|uniprotkb:KIAA2026(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831013|imex:IM-13779-3490	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"refseq:NP_001017969.2|refseq:XP_005251442.1|refseq:XP_011516063.1|refseq:XP_016869821.1|refseq:XP_016869822.1|refseq:XP_016869823.1|ensembl:ENSG00000183354.12(gene)|ensembl:ENST00000399933.8(transcript)|go:""GO:0005634""(nucleus)|interpro:IPR001487(Bromodomain)|interpro:IPR036427|interpro:IPR040214|panther:PTHR31095(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:YFhpi0l2vbyI+RDf+lYQUCb1kIc9606	intact-crc:58ECFCE26ABD65FB|rigid:MeT7TOSYX55WGMyMZs4A78OiWpU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N163	uniprotkb:A0A6L7HDR8	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|uniprotkb:B2RB79|uniprotkb:D3DSR6|ensembl:ENSP00000310670.4|ensembl:ENSP00000373930.3	intact:EBI-2813601|uniprotkb:Q6KMC4|uniprotkb:Q6HT37|uniprotkb:E9QVK2|uniprotkb:E9QVK3|uniprotkb:Q81LM9|uniprotkb:A0A0F7R6G5	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	psi-mi:a0a6l7hdr8_bacan(display_long)|uniprotkb:GBAA_4586(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831043|imex:IM-13779-3488	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066997.3|ensembl:ENSG00000158941.17(gene)|ensembl:ENST00000308511.9(transcript)|ensembl:ENST00000389279.7(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005819""(spindle)|go:""GO:0006397""(mRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0008380""(RNA splicing)|go:""GO:0009411""(response to UV)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032784""(regulation of DNA-templated transcription elongation)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0044609""(DBIRD complex)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048511""(rhythmic process)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090311""(regulation of protein deacetylation)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:2000003""(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR045353|interpro:IPR045354|mint:Q8N163|rcsb pdb:8EZ6|reactome:R-HSA-3371453|dip:DIP-38122N"	"interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR019774|go:""GO:0005506""(iron ion binding)|go:""GO:0009072""(aromatic amino acid metabolic process)|go:""GO:0016714""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen)|refseq:WP_000163221.1|interpro:IPR036329|interpro:IPR036951"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	rogid:UgqbKGjZURf/eUAUwQIMUjWsS6Q1392	intact-crc:EB1AD11686E2A1CC|rigid:yJL4u+mTmySbZJRD4DuV/Hy9n6Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C0F1	uniprotkb:Q81VV7	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519.4|ensembl:ENSP00000380009.3|ensembl:ENSP00000423153.1	intact:EBI-2809904|uniprotkb:Q6I4W1|uniprotkb:Q6KYK5	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:disa_bacan(display_long)|uniprotkb:disA(gene name)|psi-mi:disA(display_short)|uniprotkb:Cyclic di-AMP synthase(gene name synonym)|uniprotkb:Diadenylate cyclase(gene name synonym)|uniprotkb:BAS0083(locus name)|uniprotkb:BA_0082(locus name)|uniprotkb:GBAA_0082(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831076|imex:IM-13779-3493	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001035247.1|refseq:NP_001138786.1|ensembl:ENSG00000164118.13(gene)|ensembl:ENST00000296519.6(transcript)|ensembl:ENST00000396791.7(transcript)|ensembl:ENST00000503780.6(transcript)|go:""GO:0000922""(spindle pole)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007099""(centriole replication)|go:""GO:0008017""(microtubule binding)|go:""GO:0010457""(centriole-centriole cohesion)|go:""GO:0030496""(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|rcsb pdb:7PT5|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|panther:PTHR31477(orthology-group)"	"interpro:IPR018906|interpro:IPR003390(Protein of unknown function DUF147)|interpro:IPR023763|interpro:IPR010994(RuvA domain 2-like)|refseq:WP_000392168.1|interpro:IPR050338|go:""GO:0003677""(DNA binding)|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0106408""(diadenylate cyclase activity)|interpro:IPR038331|interpro:IPR036888|refseq:NP_842651.1|refseq:YP_026369.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:w05jKsotbORB695Nm44K6s+jHHk1392	intact-crc:DA1208F9154F486A|rigid:MQ5e2W4eIeoBw2AfzSZH/RbFPxU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N163	uniprotkb:A0A6L8NXR5	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|uniprotkb:B2RB79|uniprotkb:D3DSR6|ensembl:ENSP00000310670.4|ensembl:ENSP00000373930.3	intact:EBI-2815808|uniprotkb:Q6KJK8|uniprotkb:Q6HQ69|uniprotkb:E9QTE8|uniprotkb:E9QTE9|uniprotkb:Q81JM5|uniprotkb:A0A0F7R3M4	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	psi-mi:a0a6l8nxr5_bacan(display_long)|uniprotkb:GBAA_5678(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831069|imex:IM-13779-3495	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066997.3|ensembl:ENSG00000158941.17(gene)|ensembl:ENST00000308511.9(transcript)|ensembl:ENST00000389279.7(transcript)|go:""GO:0000774""(adenyl-nucleotide exchange factor activity)|go:""GO:0000785""(chromatin)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005819""(spindle)|go:""GO:0006397""(mRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0008380""(RNA splicing)|go:""GO:0009411""(response to UV)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0019899""(enzyme binding)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032784""(regulation of DNA-templated transcription elongation)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0044609""(DBIRD complex)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0048511""(rhythmic process)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090311""(regulation of protein deacetylation)|go:""GO:1902230""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:2000003""(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR045353|interpro:IPR045354|mint:Q8N163|rcsb pdb:8EZ6|reactome:R-HSA-3371453|dip:DIP-38122N"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR051309|refseq:WP_000055394.1|interpro:IPR032781"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	rogid:+cjbV1256Xv/bInsQ0cS3cXUgNE1392	intact-crc:BD85141E4913B038|rigid:mikI+nlNUAl54iLuYPv4DOMI41A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z7F0	uniprotkb:A0A6L7HER7	intact:EBI-751942|uniprotkb:O94981|uniprotkb:Q7L7Q2|uniprotkb:Q7Z7E9|uniprotkb:Q8TBQ0|ensembl:ENSP00000357304.3	intact:EBI-2831086|uniprotkb:Q6KMN0|uniprotkb:Q6HTD8|uniprotkb:E9RE16|uniprotkb:E9RE17|uniprotkb:Q81LY5|uniprotkb:A0A0F7RDF4	psi-mi:khdc4_human(display_long)|uniprotkb:KHDC4(gene name)|psi-mi:KHDC4(display_short)|uniprotkb:BLOM7(gene name synonym)|uniprotkb:Brings lots of money 7(gene name synonym)|uniprotkb:KIAA0907(gene name synonym)|uniprotkb:Pre-mRNA splicing factor protein KHDC4(gene name synonym)|uniprotkb:SNORA80EHG(gene name synonym)	psi-mi:a0a6l7her7_bacan(display_long)|uniprotkb:GBAA_4473(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831083|imex:IM-13779-3494	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055764.2|ensembl:ENSG00000132680.11(gene)|ensembl:ENST00000368321.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006376""(mRNA splice site recognition)|interpro:IPR031121|interpro:IPR036612|interpro:IPR047889|interpro:IPR047890|interpro:IPR055256|mint:Q7Z7F0|rcsb pdb:2YQR|panther:PTHR15744(orthology-group)"	refseq:WP_001093245.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JjYHRjwyj+jqt/m4RFA7bwsWEOY9606	rogid:2iqfQdAYLykAB32TZtTNdqxVh7I1392	intact-crc:3ADCB890342C3DE4|rigid:SknWTINZiNmRggNluXitWVokKFI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HPH6	uniprotkb:Q9P260	intact:EBI-2830140|uniprotkb:Q6KKN0|uniprotkb:Q6HRB3|uniprotkb:E9R3Z7|uniprotkb:E9R3Z8|uniprotkb:Q81XI0|uniprotkb:A0A0J1HL76	intact:EBI-2831057|ensembl:ENSP00000381198.2	psi-mi:a0a6l7hph6_bacan(display_long)|uniprotkb:GBAA_5257(locus name)	psi-mi:relch_human(display_long)|uniprotkb:RELCH(gene name)|psi-mi:RELCH(display_short)|uniprotkb:KIAA1468(gene name synonym)|uniprotkb:LisH domain and HEAT repeat-containing protein KIAA1468(gene name synonym)|uniprotkb:RAB11 binding and LisH domain, coiled-coil and HEAT repeat-containing(gene name synonym)|uniprotkb:RAB11-binding protein containing LisH, coiled-coil, and HEAT repeats(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831062|imex:IM-13779-3492	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR021586|interpro:IPR002831(Transcriptional regulator TrmB)|refseq:WP_000939488.1|interpro:IPR036388|interpro:IPR036390|interpro:IPR051797	"ensembl:ENSG00000134444.15(gene)|ensembl:ENST00000398130.6(transcript)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0032367""(intracellular cholesterol transport)|go:""GO:0055037""(recycling endosome)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040362|mint:Q9P260|refseq:NP_065905.2|refseq:NP_001333158.1|panther:PTHR32059(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M9WqLISUjTSw2MNoDGcq/BoXAEM1392	rogid:ovvE1tbr12EJL4w5lDT6JxN77TI9606	intact-crc:DA6B1BABDAFF5267|rigid:a3MCvGKuQYkxfpM57xKaJhNtRX0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PL93	uniprotkb:Q5T8A7	intact:EBI-2812142|uniprotkb:Q6HXW8|uniprotkb:Q6KRZ0|uniprotkb:E9R374|uniprotkb:E9R375|uniprotkb:Q81PQ4|uniprotkb:A0A0F7RGT7	intact:EBI-308500|uniprotkb:Q86WU0|uniprotkb:Q8WVV0|intact:EBI-2831095|intact:EBI-1189898|uniprotkb:Q9Y4D3|ensembl:ENSP00000349274.2|ensembl:ENSP00000385826.3|ensembl:ENSP00000473820.1|ensembl:ENSP00000474794.1|ensembl:ENSP00000474807.1	psi-mi:a0a6l8pl93_bacan(display_long)|uniprotkb:ypeB(gene name)|psi-mi:ypeB(display_short)|uniprotkb:GBAA_2747(locus name)	psi-mi:ppr26_human(display_long)|uniprotkb:PPP1R26(gene name)|psi-mi:PPP1R26(display_short)|uniprotkb:KIAA0649(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831103|imex:IM-13779-3496	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014239(Spore germination YpeB)|go:""GO:0009847""(spore germination)|refseq:WP_000943708.1|interpro:IPR025711|interpro:IPR048402"	"refseq:NP_055626.3|ensembl:ENSG00000196422.11(gene)|ensembl:ENST00000356818.7(transcript)|ensembl:ENST00000401470.3(transcript)|ensembl:ENST00000604351.5(transcript)|ensembl:ENST00000605286.5(transcript)|ensembl:ENST00000605660.1(transcript)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005730""(nucleolus)|interpro:IPR026130|interpro:IPR031474|mint:Q5T8A7|refseq:XP_005263468.1|refseq:XP_016870844.1|refseq:XP_016870845.1|refseq:XP_016870846.1|refseq:XP_016870847.1|refseq:XP_016870848.1|refseq:XP_016870849.1|refseq:XP_016870850.1|refseq:XP_016870851.1|panther:PTHR15724(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ArcU2AZZMp9ttGHYayHY+K9lpzU1392	rogid:VtYxHxj5w0Yig1U1zZFBAbJP7HY9606	intact-crc:A60FCA691C306FA4|rigid:E9gMe52gTs+6cUGvaGFNUPmwYvE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PRR8	uniprotkb:O15033	intact:EBI-2811394|uniprotkb:Q6I2G7|uniprotkb:Q6KW94|uniprotkb:E9R8J0|uniprotkb:E9R8J1|uniprotkb:Q81U80|uniprotkb:A0A0F7RLC1	intact:EBI-2831131|uniprotkb:Q7LDY1|uniprotkb:Q8IYY9|uniprotkb:B4E2C7|ensembl:ENSP00000348714.4|ensembl:ENSP00000505623.1	psi-mi:a0a6l8prr8_bacan(display_long)|uniprotkb:GBAA_1004(locus name)	psi-mi:arel1_human(display_long)|uniprotkb:AREL1(gene name)|psi-mi:AREL1(display_short)|uniprotkb:KIAA0317(gene name synonym)|uniprotkb:Apoptosis-resistant HECT-type E3 ubiquitin transferase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831138|imex:IM-13779-3498	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020843|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR011032(GroES-like)|go:""GO:0016651""(""oxidoreductase activity, acting on NAD(P)H"")|go:""GO:0070402""(NADPH binding)|refseq:WP_000902291.1|interpro:IPR036291"	"refseq:XP_011535717.1|refseq:NP_001034568.1|ensembl:ENSG00000119682.18(gene)|ensembl:ENST00000356357.9(transcript)|ensembl:ENST00000681599.1(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070979""(protein K11-linked ubiquitination)|go:""GO:1990390""(protein K33-linked ubiquitination)|interpro:IPR000569(HECT)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR035983|interpro:IPR050409|rcsb pdb:6JX5|rcsb pdb:6LOH|reactome:R-HSA-983168|panther:PTHR11254(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bJoUAV4WZkl9RHHmLvJxDPIL7Wk1392	rogid:zp9Zpv/naHGK4L5oA49hviZs72Y9606	intact-crc:BF2598A5D56EDBBB|rigid:oeL6LPEVUN+xl1ncdONCnSRm0J0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5T8A7	uniprotkb:A0A6L7HJ31	intact:EBI-308500|uniprotkb:Q86WU0|uniprotkb:Q8WVV0|intact:EBI-2831095|intact:EBI-1189898|uniprotkb:Q9Y4D3|ensembl:ENSP00000349274.2|ensembl:ENSP00000385826.3|ensembl:ENSP00000473820.1|ensembl:ENSP00000474794.1|ensembl:ENSP00000474807.1	intact:EBI-2821594|uniprotkb:Q6HZK9|uniprotkb:Q6KTJ9|uniprotkb:E9QZ58|uniprotkb:E9QZ59|uniprotkb:A0A2P0HDK6|uniprotkb:Q81RD5	psi-mi:ppr26_human(display_long)|uniprotkb:PPP1R26(gene name)|psi-mi:PPP1R26(display_short)|uniprotkb:KIAA0649(gene name synonym)	psi-mi:a0a6l7hj31_bacan(display_long)|uniprotkb:GBAA_2114(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831124|imex:IM-13779-3500	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055626.3|ensembl:ENSG00000196422.11(gene)|ensembl:ENST00000356818.7(transcript)|ensembl:ENST00000401470.3(transcript)|ensembl:ENST00000604351.5(transcript)|ensembl:ENST00000605286.5(transcript)|ensembl:ENST00000605660.1(transcript)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005730""(nucleolus)|interpro:IPR026130|interpro:IPR031474|mint:Q5T8A7|refseq:XP_005263468.1|refseq:XP_016870844.1|refseq:XP_016870845.1|refseq:XP_016870846.1|refseq:XP_016870847.1|refseq:XP_016870848.1|refseq:XP_016870849.1|refseq:XP_016870850.1|refseq:XP_016870851.1|panther:PTHR15724(orthology-group)"	"interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|go:""GO:0003677""(DNA binding)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016987""(sigma factor activity)|refseq:WP_000834222.1|interpro:IPR036388"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VtYxHxj5w0Yig1U1zZFBAbJP7HY9606	rogid:Q1Fm4WAIdfkOV/eqLShW87hNO/g1392	intact-crc:4360FDA7C36EED5D|rigid:VnSqH9jXrN3w6ObIs4PANVbmUZE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z7F0	uniprotkb:A0A4Y1WDN0	intact:EBI-751942|uniprotkb:O94981|uniprotkb:Q7L7Q2|uniprotkb:Q7Z7E9|uniprotkb:Q8TBQ0|ensembl:ENSP00000357304.3	intact:EBI-2820076|uniprotkb:Q6KJS1|uniprotkb:E9QTT6|uniprotkb:Q81JU4	psi-mi:khdc4_human(display_long)|uniprotkb:KHDC4(gene name)|psi-mi:KHDC4(display_short)|uniprotkb:BLOM7(gene name synonym)|uniprotkb:Brings lots of money 7(gene name synonym)|uniprotkb:KIAA0907(gene name synonym)|uniprotkb:Pre-mRNA splicing factor protein KHDC4(gene name synonym)|uniprotkb:SNORA80EHG(gene name synonym)	psi-mi:a0a4y1wdn0_bacan(display_long)|uniprotkb:GBAA_5601(locus name)|uniprotkb:maP3(gene name)|psi-mi:maP3(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:map(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831117|imex:IM-13779-3497	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055764.2|ensembl:ENSG00000132680.11(gene)|ensembl:ENST00000368321.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006376""(mRNA splice site recognition)|interpro:IPR031121|interpro:IPR036612|interpro:IPR047889|interpro:IPR047890|interpro:IPR055256|mint:Q7Z7F0|rcsb pdb:2YQR|panther:PTHR15744(orthology-group)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|refseq:WP_002096176.1|go:""GO:0004239""(initiator methionyl aminopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR036005"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JjYHRjwyj+jqt/m4RFA7bwsWEOY9606	rogid:OjiTf1RBDabUwoE43aSygJwUemc1392	intact-crc:16A3ACD90DE4CCD8|rigid:fo1a+BFjExhd+0oV4wa0PAJNgFo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3Q0PRJ6	uniprotkb:O43151	intact:EBI-2810680|uniprotkb:Q6KR31|uniprotkb:Q6HWZ9|uniprotkb:E9R4P7|uniprotkb:E9R4P8|uniprotkb:Q81NS9|uniprotkb:A0A0F7RCF4	intact:EBI-2831148|uniprotkb:Q8TBM9|uniprotkb:A6NEI3|uniprotkb:Q86Z24|ensembl:ENSP00000386869.3|intact:EBI-28971009|uniprotkb:K9JJH7|uniprotkb:J3KNF3	psi-mi:a0a3q0prj6_bacan(display_long)|uniprotkb:GBAA_3096(locus name)	psi-mi:tet3_human(display_long)|uniprotkb:TET3(gene name)|psi-mi:TET3(display_short)|uniprotkb:KIAA0401(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831145|imex:IM-13779-3499	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003778(Allophanate hydrolase subunit 2)|interpro:IPR052708|interpro:IPR029000|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)"	"efo:""Orphanet:684216""|ensembl:ENSG00000187605.17(gene)|ensembl:ENST00000409262.8(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001939""(female pronucleus)|go:""GO:0001940""(male pronucleus)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006493""(protein O-linked glycosylation)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008327""(methyl-CpG binding)|go:""GO:0044029""(positive regulation of gene expression via chromosomal CpG island demethylation)|go:""GO:0044727""(epigenetic programing of male pronucleus)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0070579""(DNA 5-methylcytosine dioxygenase activity)|go:""GO:0141167""(chromosomal 5-methylcytosine DNA demethylation, oxidation pathway)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR024779|interpro:IPR040175|interpro:IPR046942|mint:O43151|rcsb pdb:4Z3C|rcsb pdb:8U2Y|reactome:R-HSA-5221030|reactome:R-HSA-9821002|refseq:NP_001274420.1|refseq:XP_005264244.1|panther:PTHR23358(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NUa3lWGCm+fzNXodfOc6AoaBPi01392	rogid:D1mz+jG5GQgTI29oOFE/fXkBSC49606	intact-crc:E70AB3DFC9FDC444|rigid:0nDkzaDZmtC+jdPugRm5JfMjWVo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HA16	uniprotkb:Q2M389	intact:EBI-2814138|uniprotkb:Q6HQ53|uniprotkb:Q6F078|uniprotkb:E9RDY5|uniprotkb:E9RDY6|uniprotkb:Q81JL0|uniprotkb:A0A0F7R8Z5	intact:EBI-2563783|uniprotkb:Q8IW61|uniprotkb:Q9NVD6|uniprotkb:Q8N5W7|uniprotkb:Q2NL83|uniprotkb:Q9UPW7|ensembl:ENSP00000328062.6	psi-mi:a0a6l7ha16_bacan(display_long)|uniprotkb:GBAA_5694(locus name)	psi-mi:wasc4_human(display_long)|uniprotkb:WASHC4(gene name)|psi-mi:WASHC4(display_short)|uniprotkb:KIAA1033(gene name synonym)|uniprotkb:Strumpellin and WASH-interacting protein(gene name synonym)|uniprotkb:WASH complex subunit SWIP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831110|imex:IM-13779-3501	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000060(BCCT transporter)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_001242469.1"	"ensembl:ENSG00000136051.15(gene)|ensembl:ENST00000332180.10(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005768""(endosome)|go:""GO:0007032""(endosome organization)|go:""GO:0015031""(protein transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0031901""(early endosome membrane)|go:""GO:0034315""(regulation of Arp2/3 complex-mediated actin nucleation)|go:""GO:0050890""(cognition)|go:""GO:0050905""(neuromuscular process)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0071203""(WASH complex)|go:""GO:0140591""(nuclear envelope budding)|go:""GO:0140894""(endolysosomal toll-like receptor signaling pathway)|interpro:IPR027307|interpro:IPR028191|interpro:IPR028282|interpro:IPR028283|mint:Q2M389|refseq:NP_001280569.1|refseq:NP_056090.1|efo:""Orphanet:88616""|panther:PTHR31409(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/tOiU2i3Pj5531YNTX3x8RYSwk01392	rogid:APnP9mxAqwzKEoQFGt94Z8Y73t49606	intact-crc:90C2C7F6E9AEB42B|rigid:sP/IuLpBJMokgytesOVWgU9spfA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6AI39	uniprotkb:A0A6L8P706	intact:EBI-1012434|uniprotkb:Q5TFZ3|uniprotkb:Q92514|uniprotkb:A1L3W2|ensembl:ENSP00000313933.4|ensembl:ENSP00000377723.1	intact:EBI-2812225|uniprotkb:Q6I0N2|uniprotkb:Q6KUJ1|uniprotkb:E9QW18|uniprotkb:E9QW19|uniprotkb:A0A2P0HCA8|uniprotkb:Q81SF2	psi-mi:bicrl_human(display_long)|uniprotkb:BICRAL(gene name)|psi-mi:BICRAL(display_short)|uniprotkb:GLTSCR1L(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 1 protein-like(gene name synonym)|uniprotkb:KIAA0240(gene name synonym)	psi-mi:a0a6l8p706_bacan(display_long)|uniprotkb:GBAA_1706(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831167|imex:IM-13779-3505	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056164.1|refseq:NP_001305748.1|ensembl:ENSG00000112624.14(gene)|ensembl:ENST00000314073.10(transcript)|ensembl:ENST00000394168.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140288""(GBAF complex)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR015671(Glioma tumour suppressor candidate region gene 1)|interpro:IPR052438|panther:PTHR15572(orthology-group)"	"interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009288""(bacterial-type flagellum)|refseq:WP_001222388.1|interpro:IPR042187|interpro:IPR046358"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wmf9lC4nRlhlduBaz3ZPV8ro3vQ9606	rogid:E4keB86WCxgOoOrZylw1M6OqCFM1392	intact-crc:0226CC9A211CA96A|rigid:+KIz6kYBzcbO22e3A9dpopG89m8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6AI39	uniprotkb:A0A6L7HB40	intact:EBI-1012434|uniprotkb:Q5TFZ3|uniprotkb:Q92514|uniprotkb:A1L3W2|ensembl:ENSP00000313933.4|ensembl:ENSP00000377723.1	intact:EBI-2812761|uniprotkb:Q6I3J5|uniprotkb:Q6KXA8|uniprotkb:E9R2F8|uniprotkb:E9R2F9|uniprotkb:A0A2P0H9V3|uniprotkb:Q81VA8	psi-mi:bicrl_human(display_long)|uniprotkb:BICRAL(gene name)|psi-mi:BICRAL(display_short)|uniprotkb:GLTSCR1L(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 1 protein-like(gene name synonym)|uniprotkb:KIAA0240(gene name synonym)	psi-mi:a0a6l7hb40_bacan(display_long)|uniprotkb:GBAA_0589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831188|imex:IM-13779-3507	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056164.1|refseq:NP_001305748.1|ensembl:ENSG00000112624.14(gene)|ensembl:ENST00000314073.10(transcript)|ensembl:ENST00000394168.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140288""(GBAF complex)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR015671(Glioma tumour suppressor candidate region gene 1)|interpro:IPR052438|panther:PTHR15572(orthology-group)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR001041(Ferredoxin)|interpro:IPR006478(Formate dehydrogenase, alpha subunit)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR019574|interpro:IPR050123|interpro:IPR027467|go:""GO:0003954""(NADH dehydrogenase activity)|go:""GO:0008863""(""formate dehydrogenase (NAD+) activity"")|go:""GO:0015942""(formate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_000840648.1|interpro:IPR036010|interpro:IPR041924"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wmf9lC4nRlhlduBaz3ZPV8ro3vQ9606	rogid:QNDnbGYfnNxnQEMZtqgLWO6/cVs1392	intact-crc:75075C1E85F24BED|rigid:dC6NWKIsjvcQl2QhNhYFyH58OKU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HH45	uniprotkb:Q6AI39	intact:EBI-2810739|uniprotkb:Q6KQJ9|uniprotkb:Q6HWF0|uniprotkb:E9R0C6|uniprotkb:E9R0C7|uniprotkb:Q81N92|uniprotkb:A0A0F7RF31	intact:EBI-1012434|uniprotkb:Q5TFZ3|uniprotkb:Q92514|uniprotkb:A1L3W2|ensembl:ENSP00000313933.4|ensembl:ENSP00000377723.1	psi-mi:a0a6l7hh45_bacan(display_long)|uniprotkb:GBAA_3323(locus name)	psi-mi:bicrl_human(display_long)|uniprotkb:BICRAL(gene name)|psi-mi:BICRAL(display_short)|uniprotkb:GLTSCR1L(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 1 protein-like(gene name synonym)|uniprotkb:KIAA0240(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831160|imex:IM-13779-3502	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025672|interpro:IPR029101|go:""GO:0016020""(membrane)|refseq:WP_000180324.1"	"refseq:NP_056164.1|refseq:NP_001305748.1|ensembl:ENSG00000112624.14(gene)|ensembl:ENST00000314073.10(transcript)|ensembl:ENST00000394168.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140288""(GBAF complex)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR015671(Glioma tumour suppressor candidate region gene 1)|interpro:IPR052438|panther:PTHR15572(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WHI2kqITIISGoQqFf8Ewpzg/Ms01392	rogid:wmf9lC4nRlhlduBaz3ZPV8ro3vQ9606	intact-crc:B9489E0BC031124E|rigid:5V6mCyBtd08XqkQZKSA71WPPmRw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6AI39	uniprotkb:Q81VT8	intact:EBI-1012434|uniprotkb:Q5TFZ3|uniprotkb:Q92514|uniprotkb:A1L3W2|ensembl:ENSP00000313933.4|ensembl:ENSP00000377723.1	intact:EBI-2811891|uniprotkb:Q6I4U2	psi-mi:bicrl_human(display_long)|uniprotkb:BICRAL(gene name)|psi-mi:BICRAL(display_short)|uniprotkb:GLTSCR1L(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 1 protein-like(gene name synonym)|uniprotkb:KIAA0240(gene name synonym)	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831181|imex:IM-13779-3506	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056164.1|refseq:NP_001305748.1|ensembl:ENSG00000112624.14(gene)|ensembl:ENST00000314073.10(transcript)|ensembl:ENST00000394168.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140288""(GBAF complex)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR015671(Glioma tumour suppressor candidate region gene 1)|interpro:IPR052438|panther:PTHR15572(orthology-group)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wmf9lC4nRlhlduBaz3ZPV8ro3vQ9606	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	intact-crc:674B2E4DF1EBAC2D|rigid:Y7XHPDxRzEHmWc0xA5GA65KCsDk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3Q0PRJ6	uniprotkb:Q6AI39	intact:EBI-2810680|uniprotkb:Q6KR31|uniprotkb:Q6HWZ9|uniprotkb:E9R4P7|uniprotkb:E9R4P8|uniprotkb:Q81NS9|uniprotkb:A0A0F7RCF4	intact:EBI-1012434|uniprotkb:Q5TFZ3|uniprotkb:Q92514|uniprotkb:A1L3W2|ensembl:ENSP00000313933.4|ensembl:ENSP00000377723.1	psi-mi:a0a3q0prj6_bacan(display_long)|uniprotkb:GBAA_3096(locus name)	psi-mi:bicrl_human(display_long)|uniprotkb:BICRAL(gene name)|psi-mi:BICRAL(display_short)|uniprotkb:GLTSCR1L(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 1 protein-like(gene name synonym)|uniprotkb:KIAA0240(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831195|imex:IM-13779-3504	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003778(Allophanate hydrolase subunit 2)|interpro:IPR052708|interpro:IPR029000|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)"	"refseq:NP_056164.1|refseq:NP_001305748.1|ensembl:ENSG00000112624.14(gene)|ensembl:ENST00000314073.10(transcript)|ensembl:ENST00000394168.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140288""(GBAF complex)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR015671(Glioma tumour suppressor candidate region gene 1)|interpro:IPR052438|panther:PTHR15572(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NUa3lWGCm+fzNXodfOc6AoaBPi01392	rogid:wmf9lC4nRlhlduBaz3ZPV8ro3vQ9606	intact-crc:25276F7B13DEA39F|rigid:cbjv8tbqFotY4Dm0WKn69LGuhAY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HL57	uniprotkb:Q6AI39	intact:EBI-2813458|uniprotkb:Q6KUW4|uniprotkb:Q6I110|uniprotkb:E9RBF6|uniprotkb:E9RBF7|uniprotkb:Q81ST0|uniprotkb:A0A0F7REV0	intact:EBI-1012434|uniprotkb:Q5TFZ3|uniprotkb:Q92514|uniprotkb:A1L3W2|ensembl:ENSP00000313933.4|ensembl:ENSP00000377723.1	psi-mi:a0a6l7hl57_bacan(display_long)|uniprotkb:dinG(gene name)|psi-mi:dinG(display_short)|uniprotkb:GBAA_1565(locus name)	psi-mi:bicrl_human(display_long)|uniprotkb:BICRAL(gene name)|psi-mi:BICRAL(display_short)|uniprotkb:GLTSCR1L(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 1 protein-like(gene name synonym)|uniprotkb:KIAA0240(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831174|imex:IM-13779-3503	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR006054(DNA polymerase III, epsilon subunit)|interpro:IPR006310(DnaQ exonuclease/DinG helicase)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006260""(DNA replication)|go:""GO:0006974""(DNA damage response)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0016818""(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:""GO:0051536""(iron-sulfur cluster binding)|refseq:WP_000044932.1|interpro:IPR036397|interpro:IPR045028|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)"	"refseq:NP_056164.1|refseq:NP_001305748.1|ensembl:ENSG00000112624.14(gene)|ensembl:ENST00000314073.10(transcript)|ensembl:ENST00000394168.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140288""(GBAF complex)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|interpro:IPR015671(Glioma tumour suppressor candidate region gene 1)|interpro:IPR052438|panther:PTHR15572(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/n5TbygxYWbKH6h9wOvkhn9H1Go1392	rogid:wmf9lC4nRlhlduBaz3ZPV8ro3vQ9606	intact-crc:6C69E6721EECB1A5|rigid:JwpU3KVUp/f1HeOVr4yQNR97fuQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NWC0	uniprotkb:P05412	intact:EBI-2831236|uniprotkb:Q6KUN7|uniprotkb:Q6I0T3|uniprotkb:E9R1Z7|uniprotkb:E9R1Z8|uniprotkb:Q81SJ8|uniprotkb:A0A0F7RKY0	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1	psi-mi:a0a6l8nwc0_bacan(display_long)|uniprotkb:GBAA_1650(locus name)	psi-mi:jun_human(display_long)|uniprotkb:Transcription factor AP-1 subunit Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831241|imex:IM-13779-3512	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR022324|interpro:IPR011701(Major facilitator superfamily MFS-1)|refseq:WP_000791675.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR036259"	"refseq:NP_002219.1|panther:PTHR11462(orthology-group)|ensembl:ENSG00000177606.9(gene)|ensembl:ENST00000371222.4(transcript)|ensembl:ENST00000678696.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0019046""(release from viral latency)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035976""(transcription factor AP-1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR050946|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|rcsb pdb:8SOS|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324|reactome:R-HSA-9725370|dip:DIP-5961N|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:GOdXKVeIPcRnJPm7/xe76YF64c01392	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	intact-crc:A7DC0E3F69DD6A63|rigid:dm7YSYNMTNLEAkmMbDzj4fgW9cU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P05412	uniprotkb:A0A6L7HIZ8	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1	intact:EBI-2815899|uniprotkb:Q6HZP4|uniprotkb:Q6KTN1|uniprotkb:E9R536|uniprotkb:E9R537|uniprotkb:Q81RG9|uniprotkb:A0A0F7RD03	psi-mi:jun_human(display_long)|uniprotkb:Transcription factor AP-1 subunit Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	psi-mi:a0a6l7hiz8_bacan(display_long)|uniprotkb:GBAA_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831216|imex:IM-13779-3509	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002219.1|panther:PTHR11462(orthology-group)|ensembl:ENSG00000177606.9(gene)|ensembl:ENST00000371222.4(transcript)|ensembl:ENST00000678696.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0019046""(release from viral latency)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035976""(transcription factor AP-1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR050946|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|rcsb pdb:8SOS|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324|reactome:R-HSA-9725370|dip:DIP-5961N|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1"	refseq:WP_000498015.1|interpro:IPR034660	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	rogid:AqzZ5oTt9r3TSc7/+boX1fJqMb81392	intact-crc:9E5E6CAF1A8DEFA0|rigid:s3TxghDxbuKfUYomJQ05Gi2jVOI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3P1TQ19	uniprotkb:P05412	intact:EBI-2811472|uniprotkb:A0A0J1HLL8|uniprotkb:Q6I4W3|uniprotkb:Q6KYK7|uniprotkb:E9QSZ3|uniprotkb:E9QSZ4|uniprotkb:Q81VV9|uniprotkb:A0A2A8KMR5	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1	psi-mi:a0a3p1tq19_bacan(display_long)|uniprotkb:GBAA_0080(locus name)	psi-mi:jun_human(display_long)|uniprotkb:Transcription factor AP-1 subunit Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831209|imex:IM-13779-3511	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR050130|interpro:IPR027417|interpro:IPR028299|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034605""(cellular response to heat)|refseq:WP_000971179.1|interpro:IPR036628|interpro:IPR041546"	"refseq:NP_002219.1|panther:PTHR11462(orthology-group)|ensembl:ENSG00000177606.9(gene)|ensembl:ENST00000371222.4(transcript)|ensembl:ENST00000678696.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0019046""(release from viral latency)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035976""(transcription factor AP-1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR050946|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|rcsb pdb:8SOS|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324|reactome:R-HSA-9725370|dip:DIP-5961N|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:0gBmMjDFwwFXk8GpRSENJnWyTiI1392	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	intact-crc:86D017A4E9A6E726|rigid:XjXxNliH8UqO33FPtP4ZKonBCnc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14154	uniprotkb:Q81Y46	intact:EBI-2805660|uniprotkb:Q969R4|uniprotkb:Q96EU9|intact:EBI-2831226|ensembl:ENSP00000194118.4|ensembl:ENSP00000396225.2	intact:EBI-2812495|uniprotkb:Q6KPL0|uniprotkb:Q6HVE1	psi-mi:dele1_human(display_long)|uniprotkb:DELE1(gene name)|psi-mi:DELE1(display_short)|uniprotkb:DELE(gene name synonym)|uniprotkb:Death ligand signal enhancer(gene name synonym)|uniprotkb:KIAA0141(gene name synonym)|uniprotkb:DAP3-binding cell death enhancer 1, long form(gene name synonym)	psi-mi:hutu_bacan(display_long)|uniprotkb:hutU(gene name)|psi-mi:hutU(display_short)|uniprotkb:Imidazolonepropionate hydrolase(gene name synonym)|uniprotkb:BA_3711(locus name)|uniprotkb:GBAA_3711(locus name)|uniprotkb:BAS3441(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831223|imex:IM-13779-3510	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001136075.1|refseq:NP_055588.3|refseq:XP_005268604.1|refseq:XP_005268605.1|ensembl:ENSG00000081791.9(gene)|ensembl:ENST00000194118.8(transcript)|ensembl:ENST00000432126.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0033554""(cellular response to stress)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0140468""(HRI-mediated signaling)|go:""GO:1901526""(positive regulation of mitophagy)|go:""GO:1990641""(response to iron ion starvation)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR052748|rcsb pdb:8D9X|reactome:R-HSA-9840373|panther:PTHR45011(orthology-group)"	"interpro:IPR035085|interpro:IPR023636|interpro:IPR023637|go:""GO:0005737""(cytoplasm)|go:""GO:0016153""(urocanate hydratase activity)|go:""GO:0019556""(L-histidine catabolic process to glutamate and formamide)|go:""GO:0019557""(L-histidine catabolic process to glutamate and formate)|refseq:WP_000416715.1|interpro:IPR038364|interpro:IPR035401|interpro:IPR035400|interpro:IPR036190|refseq:NP_845974.1|refseq:YP_029697.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UBQ+baEp+eubj9KvSTnUTdJLq9g9606	rogid:bokqO9GavtjceeT8eQKHFW32guU1392	intact-crc:264090EA926F8288|rigid:g5XHvR9zGDj4sWHJjLbUDIlh2vo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14154	uniprotkb:Q6KMS8	intact:EBI-2805660|uniprotkb:Q969R4|uniprotkb:Q96EU9|intact:EBI-2831226|ensembl:ENSP00000194118.4|ensembl:ENSP00000396225.2	intact:EBI-2812678|uniprotkb:Q81M34|uniprotkb:Q6HTI7	psi-mi:dele1_human(display_long)|uniprotkb:DELE1(gene name)|psi-mi:DELE1(display_short)|uniprotkb:DELE(gene name synonym)|uniprotkb:Death ligand signal enhancer(gene name synonym)|uniprotkb:KIAA0141(gene name synonym)|uniprotkb:DAP3-binding cell death enhancer 1, long form(gene name synonym)	psi-mi:efp_bacan(display_long)|uniprotkb:efp(gene name)|psi-mi:efp(display_short)|uniprotkb:BA_4421(locus name)|uniprotkb:GBAA_4421(locus name)|uniprotkb:BAS4101(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831202|imex:IM-13779-3508	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001136075.1|refseq:NP_055588.3|refseq:XP_005268604.1|refseq:XP_005268605.1|ensembl:ENSG00000081791.9(gene)|ensembl:ENST00000194118.8(transcript)|ensembl:ENST00000432126.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006974""(DNA damage response)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0033554""(cellular response to stress)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0140468""(HRI-mediated signaling)|go:""GO:1901526""(positive regulation of mitophagy)|go:""GO:1990641""(response to iron ion starvation)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR052748|rcsb pdb:8D9X|reactome:R-HSA-9840373|panther:PTHR45011(orthology-group)"	"interpro:IPR015365(Elongation factor P, C-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR020599|interpro:IPR013185(Translation elongation factor, KOW-like)|interpro:IPR001059(Translation elongation factor P/YeiP, central)|interpro:IPR013852(Translation elongation factor P/YeiP, conserved site)|interpro:IPR011768(Translation elongation factor P)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0043043""(peptide biosynthetic process)|refseq:WP_000626507.1|refseq:YP_030351.1|refseq:NP_846649.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UBQ+baEp+eubj9KvSTnUTdJLq9g9606	rogid:IbRpaP4LNDHuGJwbXfefgJ5Xgc81392	intact-crc:0C04FAF43F54D7DA|rigid:wida1m5KtS4yzy3JMzB9TA/Dg4k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15054	uniprotkb:A0A6L7HC63	intact:EBI-2831260|uniprotkb:Q96G33|uniprotkb:C9IZ40|ensembl:ENSP00000412513.2	intact:EBI-2811370|uniprotkb:Q6KTZ3|uniprotkb:Q6I014|uniprotkb:E9QYA2|uniprotkb:E9QYA3|uniprotkb:Q81RT7|uniprotkb:A0A0F7RJ72	"psi-mi:kdm6b_human(display_long)|uniprotkb:KDM6B(gene name)|psi-mi:KDM6B(display_short)|uniprotkb:JMJD3(gene name synonym)|uniprotkb:KIAA0346(gene name synonym)|uniprotkb:JmjC domain-containing protein 3(gene name synonym)|uniprotkb:Jumonji domain-containing protein 3(gene name synonym)|uniprotkb:Lysine demethylase 6B(gene name synonym)|uniprotkb:""[histone H3]-trimethyl-L-lysine(27) demethylase 6B""(gene name synonym)"	psi-mi:a0a6l7hc63_bacan(display_long)|uniprotkb:GBAA_1950(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831262|imex:IM-13779-3513	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011522052.1|refseq:XP_011522054.1|refseq:NP_001073893.1|refseq:NP_001335645.1|refseq:XP_005256606.1|refseq:XP_005256607.1|refseq:XP_005256608.1|refseq:XP_005256609.1|refseq:XP_006721546.1|ensembl:ENSG00000132510.11(gene)|ensembl:ENST00000448097.7(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0002437""(inflammatory response to antigenic stimulus)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0014823""(response to activity)|go:""GO:0021766""(hippocampus development)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032452""(histone demethylase activity)|go:""GO:0044666""(MLL3/4 complex)|go:""GO:0045165""(cell fate commitment)|go:""GO:0045446""(endothelial cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060992""(response to fungicide)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071558""(histone H3K27me2/H3K27me3 demethylase activity)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR046941|interpro:IPR048560|interpro:IPR048562|interpro:IPR051630|mint:O15054|rcsb pdb:2XUE|rcsb pdb:2XXZ|rcsb pdb:4ASK|rcsb pdb:5FP3|rcsb pdb:5OY3|rcsb pdb:6F6D|reactome:R-HSA-2559580|reactome:R-HSA-3214842|reactome:R-HSA-9821002|dip:DIP-59912N|panther:PTHR14017(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR018044|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0071555""(cell wall organization)|refseq:WP_000825873.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LWS+OT9hMQ7YuQJJzQqmnF9qBhU9606	rogid:C+GkPog4qlTLKuFTOFPtKPvk7yQ1392	intact-crc:D7C330F1220E3FDA|rigid:O6sG+sCbtbW4meDpCDIIJmtJ/Dk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81NT6	uniprotkb:P23458	intact:EBI-2831269|uniprotkb:Q6HX06	intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204.4|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000500485.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000500841.1|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1	psi-mi:npd_bacan(display_long)|uniprotkb:cobB(gene name)|psi-mi:cobB(display_short)|uniprotkb:Regulatory protein SIR2 homolog(gene name synonym)|uniprotkb:BA_3089(locus name)|uniprotkb:GBAA_3089(locus name)|uniprotkb:BAS2874(locus name)	psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831274|imex:IM-13779-3514	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028628|interpro:IPR029035|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0032041""(histone H3K14 deacetylase activity, NAD-dependent)|go:""GO:0046969""(histone H3K9 deacetylase activity, NAD-dependent)|go:""GO:0046970""(histone H4K16 deacetylase activity, NAD-dependent)|go:""GO:0070403""(NAD+ binding)|go:""GO:0097372""(histone H3K18 deacetylase activity, NAD-dependent)|go:""GO:0140765""(histone H3K56 deacetylase activity, NAD-dependent)|go:""GO:0141222""(histone H3K4 deacetylase activity, NAD-dependent)|refseq:WP_001183818.1|interpro:IPR026591|refseq:NP_845416.3|interpro:IPR050134"	"ensembl:ENSG00000162434.14(gene)|ensembl:ENST00000342505.5(transcript)|ensembl:ENST00000671929.2(transcript)|ensembl:ENST00000671954.2(transcript)|ensembl:ENST00000672179.2(transcript)|ensembl:ENST00000672247.2(transcript)|ensembl:ENST00000672434.2(transcript)|ensembl:ENST00000672751.2(transcript)|ensembl:ENST00000699262.1(transcript)|ensembl:ENST00000699312.1(transcript)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005131""(growth hormone receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038196""(type III interferon-mediated signaling pathway)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046872""(metal ion binding)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|interpro:IPR051286|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|rcsb pdb:8EXJ|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9732724|reactome:R-HSA-9833109|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|refseq:NP_001308785.1|refseq:NP_002218.2|dip:DIP-133N|panther:PTHR45807(orthology-group)|efo:""Orphanet:574957""|efo:""Orphanet:667662""|ensembl:ENSP00000343204.4|ensembl:ENSP00000500485.1|ensembl:ENSP00000500841.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:l/hsLvfhTIe3pOwpO85QbqCgdDo1392	rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606	intact-crc:536E3C8089C33622|rigid:XGGSLsHrdQqHwDE5zznmGAT6oKI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P05412	uniprotkb:A0A6L7HLF2	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1	intact:EBI-2831251|uniprotkb:Q6KRU6|uniprotkb:Q6HXS5|uniprotkb:E9RBJ9|uniprotkb:E9RBK0|uniprotkb:Q81PK9|uniprotkb:A0A0F7RD61	psi-mi:jun_human(display_long)|uniprotkb:Transcription factor AP-1 subunit Jun(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	psi-mi:a0a6l7hlf2_bacan(display_long)|uniprotkb:GBAA_2793(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831248|imex:IM-13779-3515	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002219.1|panther:PTHR11462(orthology-group)|ensembl:ENSG00000177606.9(gene)|ensembl:ENST00000371222.4(transcript)|ensembl:ENST00000678696.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0019046""(release from viral latency)|go:""GO:0019899""(enzyme binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035497""(cAMP response element binding)|go:""GO:0035976""(transcription factor AP-1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043392""(negative regulation of DNA binding)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048545""(response to steroid hormone)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070412""(R-SMAD binding)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:0140467""(integrated stress response signaling)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1904707""(positive regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000144""(positive regulation of DNA-templated transcription initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR046347|interpro:IPR050946|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|rcsb pdb:8SOS|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324|reactome:R-HSA-9725370|dip:DIP-5961N|ensembl:ENSP00000360266.2|ensembl:ENSP00000503132.1"	"interpro:IPR003610(Carbohydrate-binding family V/XII)|interpro:IPR004302(Chitin-binding, domain 3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|refseq:WP_001065250.1|go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005576""(extracellular region)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0030246""(carbohydrate binding)|interpro:IPR036116|interpro:IPR036573|interpro:IPR051024"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	rogid:1Ikht3314xgXBF88KtkFfVE2PmA1392	intact-crc:374D2AB4A83789A0|rigid:QCMzhBEgHQNGR7iyHLj+sPadSIU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y219	uniprotkb:A0A6L7GY55	intact:EBI-946223|uniprotkb:Q9UE17|uniprotkb:Q9UE99|uniprotkb:Q9UNK8|uniprotkb:Q9Y6P9|uniprotkb:Q9Y6Q0|ensembl:ENSP00000328169.3	intact:EBI-2817427|uniprotkb:Q6KLR4|uniprotkb:Q6HSG9|uniprotkb:E9R806|uniprotkb:E9R807|uniprotkb:Q81L14|uniprotkb:A0A1S0QXE2	psi-mi:jag2_human(display_long)|uniprotkb:JAG2(gene name)|psi-mi:JAG2(display_short)	psi-mi:a0a6l7gy55_bacan(display_long)|uniprotkb:GBAA_4820(locus name)|uniprotkb:thrS2(gene name)|psi-mi:thrS2(display_short)|uniprotkb:Threonyl-tRNA synthetase(gene name synonym)|uniprotkb:thrS(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831293|imex:IM-13779-3519	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002217.3|refseq:NP_660142.1|ensembl:ENSG00000184916.9(gene)|ensembl:ENST00000331782.8(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003016""(respiratory system process)|go:""GO:0005112""(Notch binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008083""(growth factor activity)|go:""GO:0009912""(auditory receptor cell fate commitment)|go:""GO:0016331""(morphogenesis of embryonic epithelium)|go:""GO:0030154""(cell differentiation)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030217""(T cell differentiation)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042492""(gamma-delta T cell differentiation)|go:""GO:0045061""(thymic T cell selection)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:1990134""(epithelial cell apoptotic process involved in palatal shelf morphogenesis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001774(""Delta/Serrate/lag-2 (DSL) protein"")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026219|interpro:IPR049883|mint:Q9Y219|rcsb pdb:5MW5|rcsb pdb:5MW7|rcsb pdb:5MWF|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-9013507|panther:PTHR24044(orthology-group)"	"interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|interpro:IPR002320(Threonyl-tRNA synthetase, class IIa)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR047246|interpro:IPR033728|go:""GO:0000049""(tRNA binding)|go:""GO:0004829""(threonine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006435""(threonyl-tRNA aminoacylation)|go:""GO:0016740""(transferase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_000786086.1|interpro:IPR036621|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GoH5Lw1zl+3dhA4RSpJTyQ0LY4Q9606	rogid:OSzIVBvh8y5MU5GlI+ljZRDUT5o1392	intact-crc:E73BB450CF9EF474|rigid:8uo7J0NxoHif275z5TJyt8jy6tg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2P0HI89	uniprotkb:P23458	intact:EBI-2831281|uniprotkb:Q6KNJ5|uniprotkb:Q6HUB0|uniprotkb:E9QX67|uniprotkb:E9QX68|uniprotkb:Q81W61|uniprotkb:A0A0F7R7M2	intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204.4|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000500485.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000500841.1|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1	psi-mi:a0a2p0hi89_bacan(display_long)|uniprotkb:GBAA_4121(locus name)	psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831286|imex:IM-13779-3517	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR034829|interpro:IPR006343(DnaD and phage-associated region)|refseq:WP_000190234.1|interpro:IPR053162	"ensembl:ENSG00000162434.14(gene)|ensembl:ENST00000342505.5(transcript)|ensembl:ENST00000671929.2(transcript)|ensembl:ENST00000671954.2(transcript)|ensembl:ENST00000672179.2(transcript)|ensembl:ENST00000672247.2(transcript)|ensembl:ENST00000672434.2(transcript)|ensembl:ENST00000672751.2(transcript)|ensembl:ENST00000699262.1(transcript)|ensembl:ENST00000699312.1(transcript)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005131""(growth hormone receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031730""(CCR5 chemokine receptor binding)|go:""GO:0034112""(positive regulation of homotypic cell-cell adhesion)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035723""(interleukin-15-mediated signaling pathway)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0038110""(interleukin-2-mediated signaling pathway)|go:""GO:0038111""(interleukin-7-mediated signaling pathway)|go:""GO:0038113""(interleukin-9-mediated signaling pathway)|go:""GO:0038154""(interleukin-11-mediated signaling pathway)|go:""GO:0038196""(type III interferon-mediated signaling pathway)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046872""(metal ion binding)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0060397""(growth hormone receptor signaling pathway via JAK-STAT)|go:""GO:0070102""(interleukin-6-mediated signaling pathway)|go:""GO:0072540""(T-helper 17 cell lineage commitment)|go:""GO:0098586""(cellular response to virus)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|interpro:IPR051286|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|rcsb pdb:8EXJ|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-9705671|reactome:R-HSA-9732724|reactome:R-HSA-9833109|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|refseq:NP_001308785.1|refseq:NP_002218.2|dip:DIP-133N|panther:PTHR45807(orthology-group)|efo:""Orphanet:574957""|efo:""Orphanet:667662""|ensembl:ENSP00000343204.4|ensembl:ENSP00000500485.1|ensembl:ENSP00000500841.1|ensembl:ENSP00000500296.1|ensembl:ENSP00000499884.1|ensembl:ENSP00000499900.1|ensembl:ENSP00000500745.2|ensembl:ENSP00000514243.1|ensembl:ENSP00000514291.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:uuRsS/aB7YahVlaWdVwElrybRqw1392	rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606	intact-crc:DB5395AE21FBCB18|rigid:BhAZdeyfskbK68Bn8xHfj+CZ+KA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6IE81	uniprotkb:Q81X78	intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319.6|ensembl:ENSP00000425730.1|ensembl:ENSP00000482212.1|ensembl:ENSP00000483219.1	intact:EBI-2819829|uniprotkb:Q6HR14|uniprotkb:Q6KKD3	psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym)	psi-mi:eno_bacan(display_long)|uniprotkb:eno(gene name)|psi-mi:eno(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:BA_5364(locus name)|uniprotkb:GBAA_5364(locus name)|uniprotkb:BAS4985(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831307|imex:IM-13779-3518	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|refseq:XP_005263289.1|ensembl:ENSG00000077684.16(gene)|ensembl:ENST00000226319.11(transcript)|ensembl:ENST00000512960.5(transcript)|ensembl:ENST00000610919.4(transcript)|ensembl:ENST00000611140.4(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0016607""(nuclear speck)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0036064""(ciliary basal body)|go:""GO:0046872""(metal ion binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000278""(regulation of DNA biosynthetic process)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|interpro:IPR050701|mint:Q6IE81|rcsb pdb:8GDX|rcsb pdb:8GE0|reactome:R-HSA-3214847|panther:PTHR13793(orthology-group)"	"interpro:IPR000941(Enolase)|interpro:IPR020810|interpro:IPR020809|interpro:IPR020811|interpro:IPR029017|go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006096""(glycolytic process)|go:""GO:0009986""(cell surface)|refseq:WP_000103949.1|interpro:IPR036849|refseq:NP_847538.1|refseq:YP_031224.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:brla9icZHYnZBj+2WtExolD2Z489606	rogid:CKEt3RHm3qCHHHvrHx0aadVESFk1392	intact-crc:4972FAD7424F84B9|rigid:ucIsTWTV6N9CZMr0YutCzBOrUgs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96ST2	uniprotkb:Q81X85	intact:EBI-2515615|uniprotkb:Q2TB65|uniprotkb:Q9NV97|uniprotkb:Q96MI7|uniprotkb:Q9NWH8|uniprotkb:Q6P157|uniprotkb:Q8N3E8|ensembl:ENSP00000295321.4	intact:EBI-2812174|uniprotkb:Q6KKE0|uniprotkb:E9RAE3	psi-mi:iws1_human(display_long)|uniprotkb:IWS1(gene name)|psi-mi:IWS1(display_short)|uniprotkb:IWS1L(gene name synonym)|uniprotkb:IWS1-like protein(gene name synonym)	psi-mi:q81x85_bacan(display_long)|uniprotkb:GBAA_5357(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831314|imex:IM-13779-3516	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060439.2|ensembl:ENSG00000163166.15(gene)|ensembl:ENST00000295321.9(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0010793""(regulation of mRNA export from nucleus)|go:""GO:0016973""(""poly(A)+ mRNA export from nucleus"")|go:""GO:0050684""(regulation of mRNA processing)|go:""GO:0140673""(transcription elongation-coupled chromatin remodeling)|interpro:IPR017923|interpro:IPR035441|interpro:IPR051037|mint:Q96ST2|rcsb pdb:6EMR|rcsb pdb:6ZV1|rcsb pdb:6ZV4|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|panther:PTHR46010(orthology-group)"	"interpro:IPR002711(HNH endonuclease)|interpro:IPR003615(HNH nuclease)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0008270""(zinc ion binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:G7KjbkwlfWdg2VufnJfRBiS/yUs9606	rogid:cvrrKkEnADjyuk0XbSWnTXpzR/01392	intact-crc:8A8943AEAFA5344F|rigid:PUuEOautAAVE1746uQ98y/2iY24	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NQC1	uniprotkb:Q81X77	intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q6IE80|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q96GQ6|ensembl:ENSP00000378451.1	intact:EBI-2810439|uniprotkb:Q6HR13|uniprotkb:Q6KKD2	psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym)	psi-mi:gpmi_bacan(display_long)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)|uniprotkb:gpmA(gene name synonym)|uniprotkb:BA_5365(locus name)|uniprotkb:GBAA_5365(locus name)|uniprotkb:BAS4986(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831300|imex:IM-13779-3520	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143.22(gene)|ensembl:ENST00000395003.5(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:2000278""(regulation of DNA biosynthetic process)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|interpro:IPR050701|mint:Q9NQC1|reactome:R-HSA-3214847|panther:PTHR13793(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|rcsb pdb:2IFY|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030435""(sporulation resulting in formation of a cellular spore)|go:""GO:0043937""(regulation of sporulation)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|refseq:WP_001231153.1|interpro:IPR036646|refseq:NP_847539.1|refseq:YP_031225.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606	rogid:pxX2Dycc6/EBhmFHPZ5uVcHE6I41392	intact-crc:510F4D11E3D4175E|rigid:msM8kGTJXc1tcf3pM2zkunFyctI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZM3	uniprotkb:Q81ZG1	intact:EBI-308689|uniprotkb:O95062|uniprotkb:Q15812|uniprotkb:Q9HAK4|uniprotkb:Q9NXE6|uniprotkb:Q9NYG0|uniprotkb:Q9NZM2|uniprotkb:Q9ULG4|ensembl:ENSP00000347244.4	intact:EBI-2815760|uniprotkb:Q6I4A8|uniprotkb:Q6F0D2	psi-mi:itsn2_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short)|uniprotkb:KIAA1256(gene name synonym)|uniprotkb:SH3D1B(gene name synonym)|uniprotkb:SWAP(gene name synonym)|uniprotkb:SH3 domain-containing protein 1B(gene name synonym)|uniprotkb:SH3P18(gene name synonym)|uniprotkb:SH3P18-like WASP-associated protein(gene name synonym)	"psi-mi:dnlj_bacan(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:""Polydeoxyribonucleotide synthase [NAD(+)]""(gene name synonym)|uniprotkb:BAS0292(locus name)|uniprotkb:BA_0306(locus name)|uniprotkb:GBAA_0306(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831321|imex:IM-13779-3525	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006268.2|refseq:NP_062541.3|refseq:NP_671494.2|ensembl:ENSG00000198399.16(gene)|ensembl:ENST00000355123.9(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016197""(endosomal transport)|go:""GO:0030154""(cell differentiation)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0150007""(clathrin-dependent synaptic vesicle endocytosis)|go:""GO:1903861""(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR000261(""EPS15 homology (EH)"")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|interpro:IPR051480|mint:Q9NZM3|rcsb pdb:1J3T|rcsb pdb:1UDL|rcsb pdb:1UE9|rcsb pdb:1UFF|rcsb pdb:1UHF|rcsb pdb:3GF9|rcsb pdb:3JZY|rcsb pdb:4IIO|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013420|panther:PTHR11216(orthology-group)"	"interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR004149(Zinc-finger, NAD-dependent DNA ligase C4-type)|go:""GO:0003677""(DNA binding)|go:""GO:0003911""(""DNA ligase (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006288""(obsolete base-excision repair, DNA ligation)|go:""GO:0046872""(metal ion binding)|refseq:WP_000031433.1|interpro:IPR033136|interpro:IPR036420|interpro:IPR041663|refseq:NP_842855.1|refseq:YP_026572.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dxUqeWmW1uwOqgZ89UhT98/pt809606	rogid:5K+wcFPwW2YYAhlWAqUE5bwcdbc1392	intact-crc:E82861EC0D0AEFA0|rigid:EsiPO1NKNmYyP2N76JAPo2E5HvU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HLX1	uniprotkb:Q14643	intact:EBI-2816570|uniprotkb:Q6KV69|uniprotkb:Q6I1C3|uniprotkb:E9RAX9|uniprotkb:E9RAY0|uniprotkb:A0A2P0HBV5|uniprotkb:Q81T40	intact:EBI-465548|uniprotkb:Q14660|uniprotkb:Q99897|uniprotkb:E7EPX7|uniprotkb:E9PDE9|ensembl:ENSP00000497605.1	psi-mi:a0a6l7hlx1_bacan(display_long)|uniprotkb:GBAA_1449(locus name)	psi-mi:itpr1_human(display_long)|uniprotkb:ITPR1(gene name)|psi-mi:ITPR1(display_short)|uniprotkb:INSP3R1(gene name synonym)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5 trisphosphate receptor(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate receptor type 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831356|imex:IM-13779-3523	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|go:""GO:0004222""(metalloendopeptidase activity)|interpro:IPR050570|refseq:WP_000726094.1"	"efo:""Orphanet:1065""|efo:""Orphanet:208513""|efo:""Orphanet:98769""|ensembl:ENSG00000150995.21(gene)|ensembl:ENST00000649015.2(transcript)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0005220""(inositol 1,4,5-trisphosphate-gated calcium channel activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005730""(nucleolus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005955""(calcineurin complex)|go:""GO:0006816""(calcium ion transport)|go:""GO:0007165""(signal transduction)|go:""GO:0007207""(phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway)|go:""GO:0007338""(single fertilization)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015085""(calcium ion transmembrane transporter activity)|go:""GO:0015278""(intracellularly gated calcium channel activity)|go:""GO:0016020""(membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019855""(calcium channel inhibitor activity)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031088""(platelet dense granule membrane)|go:""GO:0031094""(platelet dense tubular network)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036444""(calcium import into the mitochondrion)|go:""GO:0042045""(epithelial fluid transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050849""(negative regulation of calcium-mediated signaling)|go:""GO:0050882""(voluntary musculoskeletal movement)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098695""(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:""GO:0099105""(obsolete ion channel modulating, G protein-coupled receptor signaling pathway)|go:""GO:1903514""(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:""GO:1990806""(ligand-gated ion channel signaling pathway)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR015925(Ryanodine receptor-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14643|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-418457|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|refseq:NP_001093422.2|refseq:NP_001161744.1|refseq:NP_002213.5|refseq:XP_011531985.1|dip:DIP-29714N|panther:PTHR13715(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:lRej8aG4+3FEPlHvUhrPumWqQZ81392	rogid:54BRt783vU5D9fCHNO5uFJy1N7I9606	intact-crc:F922DCF66BB2D3B1|rigid:D+1z8CBce8Iy+Tj8uhevMDvazoo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81TW1	uniprotkb:Q14573	intact:EBI-2810929|uniprotkb:Q6I247|uniprotkb:Q6KVY3	intact:EBI-351055|uniprotkb:Q14649|uniprotkb:Q5TAQ2|intact:EBI-28978202|ensembl:ENSP00000363435.4|ensembl:ENSP00000475177.1	psi-mi:adda_bacan(display_long)|uniprotkb:addA(gene name)|psi-mi:addA(display_short)|uniprotkb:DNA 3'-5' helicase AddA(gene name synonym)|uniprotkb:BAS1061(locus name)|uniprotkb:BA_1142(locus name)|uniprotkb:GBAA_1142(locus name)|uniprotkb:ATP-dependent helicase/nuclease AddA(gene name synonym)	psi-mi:itpr3_human(display_long)|uniprotkb:ITPR3(gene name)|psi-mi:ITPR3(display_short)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831335|imex:IM-13779-3524	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014152(""DNA helicase (recombination ), AddA type"")|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR038726|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0033202""(DNA helicase complex)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|refseq:WP_000970458.1|refseq:NP_843626.1|refseq:YP_027333.1"	"refseq:NP_002215.2|ensembl:ENSG00000096433.11(gene)|ensembl:ENST00000374316.9(transcript)|ensembl:ENST00000605930.3(transcript)|go:""GO:0000822""(inositol hexakisphosphate binding)|go:""GO:0005220""(inositol 1,4,5-trisphosphate-gated calcium channel activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007613""(memory)|go:""GO:0015278""(intracellularly gated calcium channel activity)|go:""GO:0016020""(membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0030168""(platelet activation)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043235""(receptor complex)|go:""GO:0043533""(inositol 1,3,4,5 tetrakisphosphate binding)|go:""GO:0045177""(apical part of cell)|go:""GO:0050909""(sensory perception of taste)|go:""GO:0050913""(sensory perception of bitter taste)|go:""GO:0050916""(sensory perception of sweet taste)|go:""GO:0050917""(sensory perception of umami taste)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0051592""(response to calcium ion)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060291""(long-term synaptic potentiation)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:0098554""(cytoplasmic side of endoplasmic reticulum membrane)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR015925(Ryanodine receptor-related)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14573|rcsb pdb:6DQJ|rcsb pdb:6DQN|rcsb pdb:6DQS|rcsb pdb:6DQV|rcsb pdb:6DQZ|rcsb pdb:6DR0|rcsb pdb:6DR2|rcsb pdb:6DRA|rcsb pdb:6DRC|rcsb pdb:6UQK|rcsb pdb:7T3P|rcsb pdb:7T3Q|rcsb pdb:7T3R|rcsb pdb:7T3T|rcsb pdb:7T3U|rcsb pdb:8TK8|rcsb pdb:8TKD|rcsb pdb:8TKE|rcsb pdb:8TKF|rcsb pdb:8TKG|rcsb pdb:8TKH|rcsb pdb:8TKI|rcsb pdb:8TL9|rcsb pdb:8TLA|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-9717207|reactome:R-HSA-983695|panther:PTHR13715(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mjbRVJQHL4JcpSJqsALgvEqgiMk1392	rogid:O+1OC4E0IrAOt+D672eXnhWHy3I9606	intact-crc:1D6259B2F084D79C|rigid:P31iPWrNgBdDC9beZKSLqY7DXNU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14571	uniprotkb:A0A0F7REH3	intact:EBI-2831342|uniprotkb:O94773|ensembl:ENSP00000370744.3	intact:EBI-2811064|uniprotkb:Q6KPV8|uniprotkb:E9R093|uniprotkb:Q81YE8	psi-mi:itpr2_human(display_long)|uniprotkb:Inositol 1,4,5-trisphosphate receptor type 2(gene name synonym)|uniprotkb:ITPR2(gene name)|psi-mi:ITPR2(display_short)|uniprotkb:IP3 receptor isoform 2(gene name synonym)|uniprotkb:Type 2 inositol 1,4,5-trisphosphate receptor(gene name synonym)	psi-mi:a0a0f7reh3_bacan(display_long)|uniprotkb:GBAA_3601(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831349|imex:IM-13779-3522	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:468666""|ensembl:ENSG00000123104.12(gene)|ensembl:ENST00000381340.8(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0005220""(inositol 1,4,5-trisphosphate-gated calcium channel activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0015085""(calcium ion transmembrane transporter activity)|go:""GO:0016020""(membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031095""(platelet dense tubular network membrane)|go:""GO:0033017""(sarcoplasmic reticulum membrane)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0071361""(cellular response to ethanol)|go:""GO:0097110""(scaffold protein binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR015925(Ryanodine receptor-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14571|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|refseq:NP_002214.2|panther:PTHR13715(orthology-group)"	refseq:WP_001116379.1|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:godRDJb6vyJG454Heg9JZhLarLc9606	rogid:kRV2TrznOHMKW2jOg5FKoFx9L+41392	intact-crc:CBA1EDF933CEE42C|rigid:J1KEMUsg2lHe4iIMWttJ5WpbmLE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3A910	uniprotkb:Q15811	intact:EBI-2815425|uniprotkb:Q6I3G2|uniprotkb:Q6KX76|uniprotkb:E9QQE7|uniprotkb:E9QQE8|uniprotkb:Q81V76|uniprotkb:A0A1Q4LW06	intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|ensembl:ENSP00000370719.3|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-11029034|intact:EBI-28971797	psi-mi:a0a6h3a910_bacan(display_long)|uniprotkb:GBAA_0624(locus name)	psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831328|imex:IM-13779-3521	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000892978.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR050764"	"ensembl:ENSG00000205726.15(gene)|ensembl:ENST00000381318.8(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006887""(exocytosis)|go:""GO:0008104""(protein localization)|go:""GO:0015031""(protein transport)|go:""GO:0016197""(endosomal transport)|go:""GO:0030027""(lamellipodium)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043005""(neuron projection)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0055037""(recycling endosome)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070064""(proline-rich region binding)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0150007""(clathrin-dependent synaptic vesicle endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR000261(""EPS15 homology (EH)"")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR032140|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|interpro:IPR051480|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408|refseq:NP_001001132.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|efo:""Orphanet:178469""|panther:PTHR11216(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/20	rogid:yaykGh1FiGgWarnwbCxPMaxi4+s1392	rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606	intact-crc:1313EB14E57B198E|rigid:8yJuMvr7WW4rQ1RGd/THHfntdcA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HRI8	uniprotkb:P05107	intact:EBI-2810366|uniprotkb:Q6F051	intact:EBI-300173|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1|ensembl:ENSP00000347279.4|ensembl:ENSP00000380948.2|ensembl:ENSP00000380950.1|ensembl:ENSP00000380955.1|ensembl:ENSP00000498780.1	psi-mi:a0a6l7hri8_bacan(display_long)|uniprotkb:GBAA_pXO2_0034(locus name)	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831404|imex:IM-13779-3528	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)|refseq:WP_000249505.1"	"efo:""Orphanet:99842""|ensembl:ENSG00000160255.19(gene)|ensembl:ENST00000355153.8(transcript)|ensembl:ENST00000397850.6(transcript)|ensembl:ENST00000397852.5(transcript)|ensembl:ENST00000397857.5(transcript)|ensembl:ENST00000652462.1(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0002523""(leukocyte migration involved in inflammatory response)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008305""(integrin complex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030369""(ICAM-3 receptor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031623""(receptor internalization)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034687""(integrin alphaL-beta2 complex)|go:""GO:0034688""(integrin alphaM-beta2 complex)|go:""GO:0034689""(integrin alphaX-beta2 complex)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0043113""(receptor clustering)|go:""GO:0043235""(receptor complex)|go:""GO:0043315""(positive regulation of neutrophil degranulation)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045123""(cellular extravasation)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045963""(negative regulation of dopamine metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1990266""(neutrophil migration)|go:""GO:2000363""(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|mint:P05107|rcsb pdb:1L3Y|rcsb pdb:1YUK|rcsb pdb:2JF1|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|rcsb pdb:4NEH|rcsb pdb:4NEN|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|rcsb pdb:7P2D|rcsb pdb:7USL|rcsb pdb:7USM|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|panther:PTHR10082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/01	rogid:CttsAiL8z2LvYlOUlkIGYJ7cxoA1392	rogid:Q/zG7M9MczNRx1TBKx4rXH+87iY9606	intact-crc:EF746F9FAF5711E1|rigid:tRWcABSnDCG28hsCJVCXW8gdvmo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6KNA9	uniprotkb:P05107	intact:EBI-2812936|uniprotkb:Q6HU26|uniprotkb:Q81MM9	intact:EBI-300173|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1|ensembl:ENSP00000347279.4|ensembl:ENSP00000380948.2|ensembl:ENSP00000380950.1|ensembl:ENSP00000380955.1|ensembl:ENSP00000498780.1	psi-mi:mete_bacan(display_long)|uniprotkb:metE(gene name)|psi-mi:metE(display_short)|uniprotkb:Cobalamin-independent methionine synthase(gene name synonym)|uniprotkb:Methionine synthase, vitamin-B12 independent isozyme(gene name synonym)|uniprotkb:BA_4218(locus name)|uniprotkb:GBAA_4218(locus name)|uniprotkb:BAS3912(locus name)	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831411|imex:IM-13779-3530	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001007635.1|interpro:IPR013215(""Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal"")|interpro:IPR006276(5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase)|interpro:IPR002629(Methionine synthase, vitamin-B12 independent)|go:""GO:0003871""(5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009086""(methionine biosynthetic process)|go:""GO:0032259""(methylation)|interpro:IPR038071|refseq:NP_846453.1|refseq:YP_030162.1"	"efo:""Orphanet:99842""|ensembl:ENSG00000160255.19(gene)|ensembl:ENST00000355153.8(transcript)|ensembl:ENST00000397850.6(transcript)|ensembl:ENST00000397852.5(transcript)|ensembl:ENST00000397857.5(transcript)|ensembl:ENST00000652462.1(transcript)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001774""(microglial cell activation)|go:""GO:0001851""(complement component C3b binding)|go:""GO:0002523""(leukocyte migration involved in inflammatory response)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006898""(receptor-mediated endocytosis)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007155""(cell adhesion)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008305""(integrin complex)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030369""(ICAM-3 receptor activity)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031623""(receptor internalization)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034687""(integrin alphaL-beta2 complex)|go:""GO:0034688""(integrin alphaM-beta2 complex)|go:""GO:0034689""(integrin alphaX-beta2 complex)|go:""GO:0035579""(specific granule membrane)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0043113""(receptor clustering)|go:""GO:0043235""(receptor complex)|go:""GO:0043315""(positive regulation of neutrophil degranulation)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0044853""(plasma membrane raft)|go:""GO:0045123""(cellular extravasation)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045963""(negative regulation of dopamine metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0090314""(positive regulation of protein targeting to membrane)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098742""(cell-cell adhesion via plasma-membrane adhesion molecules)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904996""(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:""GO:1990266""(neutrophil migration)|go:""GO:2000363""(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|mint:P05107|rcsb pdb:1L3Y|rcsb pdb:1YUK|rcsb pdb:2JF1|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|rcsb pdb:4NEH|rcsb pdb:4NEN|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|rcsb pdb:7P2D|rcsb pdb:7USL|rcsb pdb:7USM|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N|panther:PTHR10082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/01	rogid:zrEJnY1x7+9Q1u7iaM9JmIvFVAQ1392	rogid:Q/zG7M9MczNRx1TBKx4rXH+87iY9606	intact-crc:FF2BB4DA039273B5|rigid:O8f1JdSsbVyLwqVdBMqz+ZqJuIU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P5L9	uniprotkb:Q9BY32	intact:EBI-2831373|uniprotkb:Q6I3N1|uniprotkb:Q6KXE3|uniprotkb:E9R0Q6|uniprotkb:E9R0Q7|uniprotkb:A0A2P0H9Q2|uniprotkb:Q81YS9	intact:EBI-2831363|uniprotkb:Q9H3H8|uniprotkb:Q9BYN1|uniprotkb:A4UIM5|uniprotkb:Q9BYX0|uniprotkb:Q5JWH4|uniprotkb:O14878|uniprotkb:B2BCH7|uniprotkb:A2A2N2|ensembl:ENSP00000369456.3	psi-mi:a0a6l8p5l9_bacan(display_long)|uniprotkb:GBAA_0553(locus name)	psi-mi:itpa_human(display_long)|uniprotkb:ITPA(gene name)|psi-mi:ITPA(display_short)|uniprotkb:C20orf37(gene name synonym)|uniprotkb:Putative oncogene protein hlc14-06-p(gene name synonym)|uniprotkb:My049(orf name)|uniprotkb:OK/SW-cl.9(orf name)|uniprotkb:Non-canonical purine NTP pyrophosphatase(gene name synonym)|uniprotkb:Non-standard purine NTP pyrophosphatase(gene name synonym)|uniprotkb:Nucleoside-triphosphate diphosphatase(gene name synonym)|uniprotkb:Nucleoside-triphosphate pyrophosphatase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831378|imex:IM-13779-3526	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|refseq:WP_000558508.1|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|interpro:IPR050276"	"efo:""Orphanet:457375""|ensembl:ENSG00000125877.13(gene)|ensembl:ENST00000380113.8(transcript)|go:""GO:0000166""(nucleotide binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006193""(ITP catabolic process)|go:""GO:0009143""(nucleoside triphosphate catabolic process)|go:""GO:0009204""(deoxyribonucleoside triphosphate catabolic process)|go:""GO:0035870""(dITP diphosphatase activity)|go:""GO:0036220""(ITP diphosphatase activity)|go:""GO:0036222""(XTP diphosphatase activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0047429""(nucleoside triphosphate diphosphatase activity)|go:""GO:0051276""(chromosome organization)|go:""GO:0106379""(""8-oxo-(d)RTP hydrolase activity"")|interpro:IPR002637(Ham1-like protein)|interpro:IPR027502|interpro:IPR029001|rcsb pdb:2CAR|rcsb pdb:2I5D|rcsb pdb:2J4E|rcsb pdb:4F95|reactome:R-HSA-74259|reactome:R-HSA-9755088|refseq:NP_001254552.1|refseq:NP_258412.1|refseq:NP_852470.1|panther:PTHR11067(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:q+zWeUQHeoElNiyIaCZGFhL1RDU1392	rogid:5Zf8vEAHZupn8O+KmDlTMlBtvR09606	intact-crc:B282AB03ED7B6F07|rigid:0G6Ql3JHiLJx2zvS4vPbG1c63l8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AII8	uniprotkb:P18084	intact:EBI-2831385|uniprotkb:Q6KTS4|uniprotkb:Q6HZU0|uniprotkb:E9R5V5|uniprotkb:E9R5V6|uniprotkb:Q81RL5|uniprotkb:A0A0F7RK48	intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181.4	psi-mi:a0a6h3aii8_bacan(display_long)|uniprotkb:GBAA_2027(locus name)	psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831390|imex:IM-13779-3529	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000690661.1	"refseq:NP_002204.2|ensembl:ENSG00000082781.12(gene)|ensembl:ENST00000296181.9(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009986""(cell surface)|go:""GO:0016477""(cell migration)|go:""GO:0034684""(integrin alphav-beta5 complex)|go:""GO:0035313""(wound healing, spreading of epidermal cells)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043235""(receptor complex)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|rcsb pdb:7S46|rcsb pdb:7S47|rcsb pdb:7S48|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355|panther:PTHR10082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dUtDXeXbxNGFsoNzKJo8vc+yAYk1392	rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606	intact-crc:66B281520BDF7537|rigid:+47V0B5aJGcHir2hsh0Y3KxCwLU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PBD5	uniprotkb:P16144	intact:EBI-2829672|uniprotkb:Q6I2M5|uniprotkb:Q6KWF6|uniprotkb:E9QXR4|uniprotkb:E9QXR5|uniprotkb:Q81UE4|uniprotkb:A0A0F7RLM5	intact:EBI-948678|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97|ensembl:ENSP00000200181.3	psi-mi:a0a6l8pbd5_bacan(display_long)|uniprotkb:GBAA_0933(locus name)	psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831397|imex:IM-13779-3527	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006343(DnaD and phage-associated region)|interpro:IPR034829|refseq:WP_000312068.1|interpro:IPR053162	"dip:DIP-40182N|efo:""Orphanet:1114""|efo:""Orphanet:158684""|efo:""Orphanet:251393""|efo:""Orphanet:79402""|efo:""Orphanet:79403""|ensembl:ENSG00000132470.14(gene)|ensembl:ENST00000200181.8(transcript)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005730""(nucleolus)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006914""(autophagy)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008305""(integrin complex)|go:""GO:0009611""(response to wounding)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0030054""(cell junction)|go:""GO:0030056""(hemidesmosome)|go:""GO:0031252""(cell leading edge)|go:""GO:0031581""(hemidesmosome assembly)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032290""(peripheral nervous system myelin formation)|go:""GO:0035878""(nail development)|go:""GO:0043235""(receptor complex)|go:""GO:0043589""(skin morphogenesis)|go:""GO:0046847""(filopodium assembly)|go:""GO:0046872""(metal ion binding)|go:""GO:0048333""(mesodermal cell differentiation)|go:""GO:0048870""(cell motility)|go:""GO:0061450""(trophoblast cell migration)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|reactome:R-HSA-9725554|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1|panther:PTHR10082(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:zaPwWMNfIORViTxNL4kLO80PqEo1392	rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606	intact-crc:749FC00EF75C1BBD|rigid:PWacNveaTMppCtJbqqqqksnAoWs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H9A7	uniprotkb:Q00978	intact:EBI-2816086|uniprotkb:Q6KKA3|uniprotkb:Q6HQY4|uniprotkb:E9QWA3|uniprotkb:E9QWA4|uniprotkb:Q81X48|uniprotkb:A0A1J9WVL8	intact:EBI-626526|uniprotkb:D3DS61|ensembl:ENSP00000380073.3|ensembl:ENSP00000494792.1|ensembl:ENSP00000514112.1	psi-mi:a0a6l7h9a7_bacan(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:GBAA_5395(locus name)	psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831439|imex:IM-13779-3534	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000045565.1|interpro:IPR041102|interpro:IPR041552|interpro:IPR013815(ATP-grasp fold, subdomain 1)"	"refseq:NP_006075.3|ensembl:ENSG00000213928.10(gene)|ensembl:ENSG00000285048.2(gene)|ensembl:ENST00000396864.8(transcript)|ensembl:ENST00000646071.2(transcript)|ensembl:ENST00000699071.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0002376""(immune system process)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051607""(defense response to virus)|go:""GO:0070721""(ISGF3 complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q00978|reactome:R-HSA-877300|reactome:R-HSA-909733|panther:PTHR11949(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8J+yjOUWiDCOsqLZUtYwrwWzv241392	rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606	intact-crc:F1F8908CDFF89725|rigid:LefUGgKfvqTUjL7sYMdemyI8uPE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:Q96CN7	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-2805787|uniprotkb:Q7Z770|intact:EBI-2831451|ensembl:ENSP00000173527.5	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:isoc1_human(display_long)|uniprotkb:CGI-111(orf name)|uniprotkb:ISOC1(gene name)|psi-mi:ISOC1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831432|imex:IM-13779-3532	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"refseq:NP_057132.2|ensembl:ENSG00000066583.12(gene)|go:""GO:0005737""(cytoplasm)|ensembl:ENST00000173527.6(transcript)|go:""GO:0005777""(peroxisome)|interpro:IPR000868(Isochorismatase hydrolase)|interpro:IPR036380|interpro:IPR050993|mint:Q96CN7|panther:PTHR14119(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:wByhW87LRND2MYhLLnYg1/t8Cxk9606	intact-crc:855261972FE61E4A|rigid:vJBwv+kKmJdTeeHJSTu2Px6xir8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20702	uniprotkb:Q81WU4	intact:EBI-2568308|uniprotkb:Q8IVA6|ensembl:ENSP00000268296.5	intact:EBI-2830714|uniprotkb:Q6KP72|uniprotkb:Q6HUZ7	psi-mi:itax_human(display_long)|uniprotkb:ITGAX(gene name)|psi-mi:ITGAX(display_short)|uniprotkb:CD11C(gene name synonym)|uniprotkb:Leukocyte adhesion glycoprotein p150,95 alpha chain(gene name synonym)|uniprotkb:Leukocyte adhesion receptor p150,95(gene name synonym)|uniprotkb:Leu M5(gene name synonym)|uniprotkb:CD11 antigen-like family member C(gene name synonym)	psi-mi:pept_bacan(display_long)|uniprotkb:pepT(gene name)|psi-mi:pepT(display_short)|uniprotkb:pepT-1(gene name synonym)|uniprotkb:Aminotripeptidase(gene name synonym)|uniprotkb:Tripeptide aminopeptidase(gene name synonym)|uniprotkb:BA_3872(locus name)|uniprotkb:GBAA_3872(locus name)|uniprotkb:BAS3588(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831418|imex:IM-13779-3533	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000878.2|refseq:NP_001273304.1|ensembl:ENSG00000140678.17(gene)|ensembl:ENST00000268296.9(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008305""(integrin complex)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031643""(positive regulation of myelination)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034113""(heterotypic cell-cell adhesion)|go:""GO:0034689""(integrin alphaX-beta2 complex)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0051607""(defense response to virus)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:1905956""(positive regulation of endothelial tube morphogenesis)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|interpro:IPR048285|interpro:IPR048633|rcsb pdb:1N3Y|rcsb pdb:2LUV|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|rcsb pdb:4NEH|rcsb pdb:4NEN|rcsb pdb:5ES4|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-3000178|reactome:R-HSA-6785807|reactome:R-HSA-6798695|dip:DIP-59369N|panther:PTHR23220(orthology-group)"	"interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR010161(Peptidase M20B, tripeptide aminopeptidase)|rcsb pdb:3IFE|refseq:WP_000656974.1|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0045148""(tripeptide aminopeptidase activity)|interpro:IPR036264|refseq:NP_846121.1|refseq:YP_029841.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oj61gn0Aj4FhUc+DejmnXrUqi6E9606	rogid:Oha1BGkI+0d8YvKh6DtzsAuCnYs1392	intact-crc:D1B1FF85464E42BB|rigid:ELT/vzLSa1g/xu/nBF24s/EWlgo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96CN7	uniprotkb:Q81X77	intact:EBI-2805787|uniprotkb:Q7Z770|intact:EBI-2831451|ensembl:ENSP00000173527.5	intact:EBI-2810439|uniprotkb:Q6HR13|uniprotkb:Q6KKD2	psi-mi:isoc1_human(display_long)|uniprotkb:CGI-111(orf name)|uniprotkb:ISOC1(gene name)|psi-mi:ISOC1(display_short)	psi-mi:gpmi_bacan(display_long)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)|uniprotkb:gpmA(gene name synonym)|uniprotkb:BA_5365(locus name)|uniprotkb:GBAA_5365(locus name)|uniprotkb:BAS4986(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831425|imex:IM-13779-3531	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057132.2|ensembl:ENSG00000066583.12(gene)|go:""GO:0005737""(cytoplasm)|ensembl:ENST00000173527.6(transcript)|go:""GO:0005777""(peroxisome)|interpro:IPR000868(Isochorismatase hydrolase)|interpro:IPR036380|interpro:IPR050993|mint:Q96CN7|panther:PTHR14119(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|rcsb pdb:2IFY|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030435""(sporulation resulting in formation of a cellular spore)|go:""GO:0043937""(regulation of sporulation)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|refseq:WP_001231153.1|interpro:IPR036646|refseq:NP_847539.1|refseq:YP_031225.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wByhW87LRND2MYhLLnYg1/t8Cxk9606	rogid:pxX2Dycc6/EBhmFHPZ5uVcHE6I41392	intact-crc:1D31E2972C80C61A|rigid:ON0Ajlm8y7tFI8M6ImuECl3KHjc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96CN7	uniprotkb:A0A6L8P543	intact:EBI-2805787|uniprotkb:Q7Z770|intact:EBI-2831451|ensembl:ENSP00000173527.5	intact:EBI-2831446|uniprotkb:Q6KP06|uniprotkb:Q6HUS4|uniprotkb:E9RBD7|uniprotkb:E9RBD8|uniprotkb:Q81WM4|uniprotkb:A0A1J9WLL3|uniprotkb:A0A348A873	psi-mi:isoc1_human(display_long)|uniprotkb:CGI-111(orf name)|uniprotkb:ISOC1(gene name)|psi-mi:ISOC1(display_short)	psi-mi:a0a6l8p543_bacan(display_long)|uniprotkb:GBAA_3949(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831456|imex:IM-13779-3539	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057132.2|ensembl:ENSG00000066583.12(gene)|go:""GO:0005737""(cytoplasm)|ensembl:ENST00000173527.6(transcript)|go:""GO:0005777""(peroxisome)|interpro:IPR000868(Isochorismatase hydrolase)|interpro:IPR036380|interpro:IPR050993|mint:Q96CN7|panther:PTHR14119(orthology-group)"	interpro:IPR007546(Protein of unknown function DUF503)|refseq:WP_000582364.1|interpro:IPR036746	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wByhW87LRND2MYhLLnYg1/t8Cxk9606	rogid:ykzWHEZSv4F+sz6Q/P6cmiX5ZIc1392	intact-crc:D60E609A599D8343|rigid:QX+8reP4VQAEqOJmgjU/Ds0rYbE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PM02	uniprotkb:P05154	intact:EBI-2817270|uniprotkb:Q6KSX8|uniprotkb:Q6HYX9|uniprotkb:E9R3N4|uniprotkb:E9R3N5|uniprotkb:Q81QR0|uniprotkb:A0A1Q4M066	intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203.7|ensembl:ENSP00000450837.1|ensembl:ENSP00000451126.1|ensembl:ENSP00000451610.1	psi-mi:a0a6l8pm02_bacan(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:GBAA_2359(locus name)	psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831484|imex:IM-13779-3537	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|interpro:IPR026843|go:""GO:0004519""(endonuclease activity)|go:""GO:0006260""(DNA replication)|go:""GO:0006310""(DNA recombination)|go:""GO:0008408""(3'-5' exonuclease activity)|interpro:IPR050535|interpro:IPR041796|refseq:WP_000765133.1"	"refseq:NP_000615.3|ensembl:ENSG00000188488.14(gene)|ensembl:ENST00000329597.12(transcript)|ensembl:ENST00000553780.5(transcript)|ensembl:ENST00000554276.1(transcript)|ensembl:ENST00000554866.5(transcript)|go:""GO:0001972""(retinoic acid binding)|go:""GO:0002020""(protease binding)|go:""GO:0002080""(acrosomal membrane)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006869""(lipid transport)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007342""(fusion of sperm to egg plasma membrane involved in single fertilization)|go:""GO:0008201""(heparin binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031094""(platelet dense tubular network)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0032190""(acrosin binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036024""(protein C inhibitor-TMPRSS7 complex)|go:""GO:0036025""(protein C inhibitor-TMPRSS11E complex)|go:""GO:0036026""(protein C inhibitor-PLAT complex)|go:""GO:0036027""(protein C inhibitor-PLAU complex)|go:""GO:0036028""(protein C inhibitor-thrombin complex)|go:""GO:0036029""(protein C inhibitor-KLK3 complex)|go:""GO:0036030""(protein C inhibitor-plasma kallikrein complex)|go:""GO:0051346""(negative regulation of hydrolase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097181""(protein C inhibitor-coagulation factor V complex)|go:""GO:0097182""(protein C inhibitor-coagulation factor Xa complex)|go:""GO:0097183""(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P05154|rcsb pdb:1LQ8|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N|panther:PTHR11461(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:bA4y9/qX/Z5XJdKpWZDK8nb9YME1392	rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606	intact-crc:DF4C1EA68BEB021C|rigid:Em84dY7r22MzMTNyz/hlE8AUGNE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13576	uniprotkb:Q81QB6	intact:EBI-357571|uniprotkb:J3KR91|uniprotkb:A8K4V1|uniprotkb:B7Z8A4|ensembl:ENSP00000274364.6	intact:EBI-2813022|uniprotkb:Q6KSJ4|uniprotkb:Q6HYJ3	psi-mi:iqga2_human(display_long)|uniprotkb:IQGAP2(gene name)|psi-mi:IQGAP2(display_short)	psi-mi:iola2_bacan(display_long)|uniprotkb:iolA2(gene name)|psi-mi:iolA2(display_short)|uniprotkb:Methylmalonate-semialdehyde dehydrogenase 2(gene name synonym)|uniprotkb:BAS2334(locus name)|uniprotkb:BA_2513(locus name)|uniprotkb:GBAA_2513(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831470|imex:IM-13779-3538	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_001272391.1|refseq:NP_006624.2|ensembl:ENSG00000145703.17(gene)|ensembl:ENST00000274364.11(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0009986""(cell surface)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030175""(filopodium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070493""(thrombin-activated receptor signaling pathway)|go:""GO:0071933""(Arp2/3 complex binding)|go:""GO:1903479""(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|mint:Q13576|rcsb pdb:3IEZ|rcsb pdb:4EZA|rcsb pdb:5CJP|reactome:R-HSA-5626467|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-27542N|panther:PTHR14149(orthology-group)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR010061(Methylmalonate-semialdehyde dehydrogenase)|interpro:IPR023510|go:""GO:0004491""(""methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"")|go:""GO:0006210""(thymine catabolic process)|go:""GO:0006574""(valine catabolic process)|go:""GO:0018478""(""malonate-semialdehyde dehydrogenase (acetylating) activity"")|go:""GO:0019310""(inositol catabolic process)|refseq:WP_000218128.1|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:NP_844885.1|refseq:YP_028595.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gmxbOFcisiWIsQrHFQCoI5y49T09606	rogid:TaEXSia0nVVJlDhMy7qd6AdehPI1392	intact-crc:57ED076ADFE591B2|rigid:cuVKzjnRuKy3fIPKj7z+Lry4pLE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1WDL3	uniprotkb:Q13576	intact:EBI-2822569|uniprotkb:Q6I2U2|uniprotkb:Q6KWM1|uniprotkb:E9R9U1|uniprotkb:E9R9U2|uniprotkb:Q81UL3|uniprotkb:A0A0F7RLQ9	intact:EBI-357571|uniprotkb:J3KR91|uniprotkb:A8K4V1|uniprotkb:B7Z8A4|ensembl:ENSP00000274364.6	psi-mi:a0a4y1wdl3_bacan(display_long)|uniprotkb:GBAA_0855(locus name)	psi-mi:iqga2_human(display_long)|uniprotkb:IQGAP2(gene name)|psi-mi:IQGAP2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831463|imex:IM-13779-3535	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR018313|go:""GO:0005886""(plasma membrane)|go:""GO:0015276""(ligand-gated monoatomic ion channel activity)|refseq:WP_000732844.1"	"refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_001272391.1|refseq:NP_006624.2|ensembl:ENSG00000145703.17(gene)|ensembl:ENST00000274364.11(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0009986""(cell surface)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0030027""(lamellipodium)|go:""GO:0030175""(filopodium)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0034314""(Arp2/3 complex-mediated actin nucleation)|go:""GO:0051015""(actin filament binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070493""(thrombin-activated receptor signaling pathway)|go:""GO:0071933""(Arp2/3 complex binding)|go:""GO:1903479""(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|mint:Q13576|rcsb pdb:3IEZ|rcsb pdb:4EZA|rcsb pdb:5CJP|reactome:R-HSA-5626467|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-27542N|panther:PTHR14149(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Io1G55qV3qC/RS4aSI6QR8evBQ81392	rogid:gmxbOFcisiWIsQrHFQCoI5y49T09606	intact-crc:43839232A5895D1D|rigid:NtJG2D0am5U+xCkXEL53hQLoV/4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VT8	uniprotkb:P46940	intact:EBI-2811891|uniprotkb:Q6I4U2	intact:EBI-297509|intact:EBI-25601492|uniprotkb:A7MBM3|ensembl:ENSP00000268182.5	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831477|imex:IM-13779-3536	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"ensembl:ENSG00000140575.13(gene)|ensembl:ENST00000268182.10(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010761""(fibroblast migration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030424""(axon)|go:""GO:0030426""(growth cone)|go:""GO:0030496""(midbody)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035305""(negative regulation of dephosphorylation)|go:""GO:0036057""(slit diaphragm)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0043005""(neuron projection)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0051015""(actin filament binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070836""(caveola assembly)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0072015""(podocyte development)|go:""GO:1903479""(mitotic actomyosin contractile ring assembly actin filament organization)|go:""GO:1990138""(neuron projection extension)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N|panther:PTHR14149(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	intact-crc:77FEF58E4033F214|rigid:uaeLSHHNJZU7wFcX/umu4yf596g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:Q8TEX9	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453.6|ensembl:ENSP00000494795.1	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831491|imex:IM-13779-3540	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"refseq:NP_078934.3|panther:PTHR10527(orthology-group)|ensembl:ENSG00000196497.17(gene)|ensembl:ENSG00000285248.2(gene)|ensembl:ENST00000354464.11(transcript)|ensembl:ENST00000644546.2(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0008139""(nuclear localization sequence binding)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0061608""(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK|rcsb pdb:7UNK|rcsb pdb:8DYO|dip:DIP-32944N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	intact-crc:E31388B8CF9DC2EF|rigid:d+kDqB4mBC2CCQQdL9CkhBF8O4I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13423	uniprotkb:P46940	intact:EBI-456868|uniprotkb:Q937W2|uniprotkb:Q937W3|uniprotkb:Q9F5R7|uniprotkb:Q9KH69|uniprotkb:Q9RQU2	intact:EBI-297509|intact:EBI-25601492|uniprotkb:A7MBM3|ensembl:ENSP00000268182.5	psi-mi:pag_bacan(display_long)|uniprotkb:PA-83(gene name synonym)|uniprotkb:Anthrax toxins translocating protein(gene name synonym)|uniprotkb:pagA(gene name)|psi-mi:pagA(display_short)|uniprotkb:pag(gene name synonym)|uniprotkb:pXO1-110(locus name)|uniprotkb:BXA0164(locus name)|uniprotkb:GBAA_pXO1_0164(locus name)	psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831498|imex:IM-13779-3544	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"mint:P13423|refseq:NP_052806.1|refseq:WP_000746487.1|refseq:WP_000746486.1|refseq:WP_000746488.1|go:""GO:0005576""(extracellular region)|go:""GO:0016020""(membrane)|go:""GO:0020002""(host cell plasma membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0044164""(host cell cytosol)|go:""GO:0044175""(host cell endosome membrane)|go:""GO:0044533""(obsolete positive regulation of apoptotic process in another organism)|go:""GO:0046872""(metal ion binding)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0090729""(toxin activity)|interpro:IPR003896(Bacterial exotoxin B)|interpro:IPR011658(PA14)|interpro:IPR027439|interpro:IPR027441|interpro:IPR035088|interpro:IPR035331|interpro:IPR037149|interpro:IPR037524|interpro:IPR048853|rcsb pdb:1ACC|rcsb pdb:1T6B|rcsb pdb:1TZN|rcsb pdb:1TZO|rcsb pdb:3ETB|rcsb pdb:3INO|rcsb pdb:3J9C|rcsb pdb:3KWV|rcsb pdb:3MHZ|rcsb pdb:3Q8A|rcsb pdb:3Q8B|rcsb pdb:3Q8C|rcsb pdb:3Q8E|rcsb pdb:3Q8F|rcsb pdb:3TEW|rcsb pdb:3TEX|rcsb pdb:3TEY|rcsb pdb:3TEZ|rcsb pdb:4EE2|rcsb pdb:4H2A|rcsb pdb:4NAM|rcsb pdb:5FR3|rcsb pdb:6PSN|rcsb pdb:6UJI|rcsb pdb:6UZB|rcsb pdb:6UZD|rcsb pdb:6UZE|rcsb pdb:6VRA|rcsb pdb:6WJJ|rcsb pdb:6ZXJ|rcsb pdb:6ZXK|rcsb pdb:6ZXL|rcsb pdb:7KXR|rcsb pdb:7O85|reactome:R-HSA-5210891|dip:DIP-29841N"	"ensembl:ENSG00000140575.13(gene)|ensembl:ENST00000268182.10(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010761""(fibroblast migration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030424""(axon)|go:""GO:0030426""(growth cone)|go:""GO:0030496""(midbody)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035305""(negative regulation of dephosphorylation)|go:""GO:0036057""(slit diaphragm)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0043005""(neuron projection)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045860""(positive regulation of protein kinase activity)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0051015""(actin filament binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070836""(caveola assembly)|go:""GO:0071277""(cellular response to calcium ion)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0072015""(podocyte development)|go:""GO:1903479""(mitotic actomyosin contractile ring assembly actin filament organization)|go:""GO:1990138""(neuron projection extension)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N|panther:PTHR14149(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:xLr/ydN4I0qJ46G/8A3JfZqAbyE1392	rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606	intact-crc:C345C78A6656EA0F|rigid:e8abHKKdjODct5I7DOEmM4jDUxE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WYH8	uniprotkb:A0A6L8PBA4	intact:EBI-488533|ensembl:ENSP00000322142.7|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54	intact:EBI-2811481|uniprotkb:Q6HWM6|uniprotkb:Q6KQR8|uniprotkb:E9R9K3|uniprotkb:E9R9K4|uniprotkb:Q81NG1|uniprotkb:A0A0F7RFB0	psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short)	psi-mi:a0a6l8pba4_bacan(display_long)|uniprotkb:GBAA_3236(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831505|imex:IM-13779-3541	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000168395.16(gene)|ensembl:ENST00000313552.11(transcript)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006275""(regulation of DNA replication)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006473""(protein acetylation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0035064""(methylated histone binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045926""(negative regulation of growth)|go:""GO:0046872""(metal ion binding)|go:""GO:0048144""(fibroblast proliferation)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0050793""(regulation of developmental process)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070776""(MOZ/MORF histone acetyltransferase complex)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0140889""(DNA replication-dependent chromatin disassembly)|go:""GO:1903706""(regulation of hemopoiesis)|go:""GO:2000278""(regulation of DNA biosynthetic process)|go:""GO:2001235""(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_115705.2|panther:PTHR10333(orthology-group)|refseq:NP_001317091.1|dip:DIP-32511N"	"interpro:IPR027278|interpro:IPR005966(Pyridoxal phosphate-dependent deaminase)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|go:""GO:0019148""(D-cysteine desulfhydrase activity)|refseq:WP_001046577.1|interpro:IPR036052"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dwJLwzNcL9866noaSFznDKeulRU9606	rogid:wppwoIBS9yJ6YJCkewhEheENTIg1392	intact-crc:5BF94CAE4C0DA686|rigid:wYwucGk6YmzNf44+HFDQE2Zo6KM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7RE19	uniprotkb:Q27J81	intact:EBI-2809783|uniprotkb:Q6KPM6|uniprotkb:Q6HVF7|uniprotkb:E9QS28|uniprotkb:E9QS29|uniprotkb:Q81Y62	intact:EBI-2557882|uniprotkb:Q6PK22|uniprotkb:Q86TR7|uniprotkb:Q9H6N1|uniprotkb:Q9BRM1|uniprotkb:Q27J83|uniprotkb:Q69YL8|uniprotkb:Q6P1X7|intact:EBI-28987364|ensembl:ENSP00000376410.4	psi-mi:a0a0f7re19_bacan(display_long)|uniprotkb:GBAA_3695(locus name)	psi-mi:inf2_human(display_long)|uniprotkb:INF2(gene name)|psi-mi:INF2(display_short)|uniprotkb:C14orf151(gene name synonym)|uniprotkb:C14orf173(gene name synonym)|uniprotkb:HBEBP2-binding protein C(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831512|imex:IM-13779-3543	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001119(S-layer homology region)|interpro:IPR051465|go:""GO:0030115""(S-layer)|interpro:IPR032247"	"efo:""Orphanet:656""|efo:""Orphanet:93114""|ensembl:ENSG00000203485.14(gene)|ensembl:ENST00000392634.9(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005884""(actin filament)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0090140""(regulation of mitochondrial fission)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:Q27J81|rcsb pdb:8RV2|rcsb pdb:9AZ4|rcsb pdb:9AZP|rcsb pdb:9AZQ|rcsb pdb:9B03|rcsb pdb:9B0K|rcsb pdb:9FJN|rcsb pdb:9FJW|refseq:NP_001026884.3|refseq:NP_071934.3|refseq:NP_116103.1|panther:PTHR45691(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RZeq/OQN8n8nnEe280+/uO/FFX01392	rogid:Vtx6fZtKGr2qGWX70naf5REXWTw9606	intact-crc:EF7CA6858F8193E0|rigid:LShOxD1uqnIrCA22R1lrndn3Jak	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48551	uniprotkb:A0A6L8PL26	intact:EBI-958408|uniprotkb:A8KAJ4|uniprotkb:Q6FHD7|uniprotkb:D3DSE8|uniprotkb:D3DSE9|uniprotkb:Q15467|ensembl:ENSP00000343957.5|ensembl:ENSP00000508013.1	intact:EBI-2813429|uniprotkb:Q6KV67|uniprotkb:Q6I1C0|uniprotkb:E9QVF8|uniprotkb:E9QVF9|uniprotkb:Q81T38|uniprotkb:A0A2B6BVS3	psi-mi:inar2_human(display_long)|uniprotkb:IFNAR2(gene name)|psi-mi:IFNAR2(display_short)|uniprotkb:IFNARB(gene name synonym)|uniprotkb:Type I interferon receptor 2(gene name synonym)|uniprotkb:IFNABR(gene name synonym)|uniprotkb:Interferon alpha binding protein(gene name synonym)	psi-mi:a0a6l8pl26_bacan(display_long)|uniprotkb:GBAA_1451(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831519|imex:IM-13779-3542	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:431166""|dip:DIP-945N|ensembl:ENSG00000159110.22(gene)|ensembl:ENST00000342136.9(transcript)|ensembl:ENST00000683941.1(transcript)|go:""GO:0004905""(type I interferon receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0008269""(JAK pathway signal transduction adaptor activity)|go:""GO:0009615""(response to virus)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019955""(cytokine binding)|go:""GO:0019962""(type I interferon binding)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0042018""(interleukin-22 receptor activity)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0098586""(cellular response to virus)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116|interpro:IPR050650|mint:P48551|rcsb pdb:1N6U|rcsb pdb:1N6V|rcsb pdb:2HYM|rcsb pdb:2KZ1|rcsb pdb:2LAG|rcsb pdb:3S8W|rcsb pdb:3S9D|rcsb pdb:3SE3|rcsb pdb:3SE4|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191|reactome:R-HSA-9705671|reactome:R-HSA-9833109|refseq:NP_000865.2|refseq:NP_001276054.1|refseq:NP_001276055.1|refseq:NP_001276057.1|refseq:NP_997467.1|refseq:NP_997468.1|panther:PTHR20859(orthology-group)"	interpro:IPR007295(Protein of unknown function DUF402)|refseq:WP_000824675.1|interpro:IPR035930	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:n9jPySJ4jlqmT6QgmSlEeNLwUog9606	rogid:DlrYBPoUvvBvOf1aVBbhx4YloBI1392	intact-crc:D24DAAD385343F2B|rigid:AXObqVSEph5bg479O8Esiru5wJQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P32927	uniprotkb:A0A6L8PPL7	intact:EBI-1809771|ensembl:ENSP00000384053.3|uniprotkb:Q5JZI1|uniprotkb:Q6ICE0	intact:EBI-2820855|uniprotkb:Q6KKI9|uniprotkb:Q6HR71|uniprotkb:E9QYW1|uniprotkb:E9QYW2|uniprotkb:A0A2P0HL78|uniprotkb:Q81XD7	psi-mi:il3rb_human(display_long)|uniprotkb:CSF2RB(gene name)|psi-mi:CSF2RB(display_short)|uniprotkb:IL3RB(gene name synonym)|uniprotkb:IL5RB(gene name synonym)|uniprotkb:GM-CSF/IL-3/IL-5 receptor common beta subunit(gene name synonym)|uniprotkb:CDw131(gene name synonym)	psi-mi:a0a6l8ppl7_bacan(display_long)|uniprotkb:GBAA_5302(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831553|imex:IM-13779-3548	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100368.15(gene)|ensembl:ENST00000403662.8(transcript)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0007259""(cell surface receptor signaling pathway via JAK-STAT)|go:""GO:0007585""(respiratory gaseous exchange by respiratory system)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0030526""(granulocyte macrophage colony-stimulating factor receptor complex)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0036016""(cellular response to interleukin-3)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0038043""(interleukin-5-mediated signaling pathway)|go:""GO:0038156""(interleukin-3-mediated signaling pathway)|go:""GO:0038157""(granulocyte-macrophage colony-stimulating factor signaling pathway)|go:""GO:0070665""(positive regulation of leukocyte proliferation)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011365(Cytokine IL-3/IL-5/GM-CSF receptor common beta chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR048668|mint:P32927|rcsb pdb:1C8P|rcsb pdb:1EGJ|rcsb pdb:1GH7|rcsb pdb:2GYS|rcsb pdb:2NA8|rcsb pdb:2NA9|rcsb pdb:4NKQ|rcsb pdb:5DWU|rcsb pdb:8TLD|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-5683826|reactome:R-HSA-5688849|reactome:R-HSA-5688890|reactome:R-HSA-912526|refseq:NP_000386.1|refseq:XP_005261397.1|efo:""Orphanet:264675""|panther:PTHR23037(orthology-group)|dip:DIP-127N"	"interpro:IPR016040(""NAD(P)-binding"")|go:""GO:0016646""(oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor)|refseq:WP_000689817.1|interpro:IPR036291|interpro:IPR051606"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NZgW441MxxYgvAaUOGnwbuyj6uw9606	rogid:1k4lxbZKPNfPGD/o4O59XbFC4EM1392	intact-crc:B6D5BAB356E95BC6|rigid:LAJwS2EJJrRC18ToqwH0rNmNveY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AD48	uniprotkb:P24394	intact:EBI-2831541|uniprotkb:Q6HZV4|uniprotkb:Q6KTT6|uniprotkb:E9R5M6|uniprotkb:E9R5M7|uniprotkb:Q81RN0|uniprotkb:A0A0F7RJ26	intact:EBI-367009|uniprotkb:Q96P01|uniprotkb:Q9H181|uniprotkb:Q9H182|uniprotkb:Q9H183|uniprotkb:Q9H184|uniprotkb:Q9H185|uniprotkb:Q9H186|uniprotkb:Q9H187|uniprotkb:Q9H188|uniprotkb:B4E076|uniprotkb:B9EKU8|uniprotkb:H3BSY5|ensembl:ENSP00000379111.2|ensembl:ENSP00000441667.2	psi-mi:a0a6h3ad48_bacan(display_long)|uniprotkb:GBAA_2012(locus name)	psi-mi:il4ra_human(display_long)|uniprotkb:IL4R(gene name)|psi-mi:IL4R(display_short)|uniprotkb:582J2.1(orf name)|uniprotkb:IL4RA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831546|imex:IM-13779-3547	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR038728|interpro:IPR004761(Spore germination GerAB)|refseq:WP_002036214.1|go:""GO:0009847""(spore germination)|go:""GO:0016020""(membrane)"	"refseq:NP_001244336.1|refseq:NP_000409.1|refseq:NP_001244335.1|ensembl:ENSG00000077238.14(gene)|ensembl:ENST00000395762.7(transcript)|ensembl:ENST00000543915.6(transcript)|go:""GO:0002532""(production of molecular mediator involved in inflammatory response)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0004913""(interleukin-4 receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035771""(interleukin-4-mediated signaling pathway)|go:""GO:0042832""(defense response to protozoan)|go:""GO:0043032""(positive regulation of macrophage activation)|go:""GO:0043235""(receptor complex)|go:""GO:0043306""(positive regulation of mast cell degranulation)|go:""GO:0045063""(T-helper 1 cell differentiation)|go:""GO:0045064""(T-helper 2 cell differentiation)|go:""GO:0045626""(negative regulation of T-helper 1 cell differentiation)|go:""GO:0045630""(positive regulation of T-helper 2 cell differentiation)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1901741""(positive regulation of myoblast fusion)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015319(Interleukin-4 receptor alpha chain, N-terminal)|interpro:IPR036116|mint:P24394|rcsb pdb:1IAR|rcsb pdb:1IRS|rcsb pdb:3BPL|rcsb pdb:3BPN|rcsb pdb:3BPO|rcsb pdb:5E4E|rcsb pdb:6OEL|rcsb pdb:6WGL|rcsb pdb:8K4Q|reactome:R-HSA-6785807|refseq:XP_011544127.1|refseq:XP_011544128.1|refseq:XP_011544129.1|dip:DIP-3223N|panther:PTHR23037(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t3TeX71Ppmqs70TMXbjWkzcRI941392	rogid:18E1cLQsvHGc0WRFqUzuGssLVg09606	intact-crc:F7687B7A279D3284|rigid:OoysN2uTHFVfWaaU5UTDpwvhpCo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30740	uniprotkb:Q9K5J5	intact:EBI-2831526|uniprotkb:Q53FB9|uniprotkb:A8K5L2|uniprotkb:Q5W0E1|uniprotkb:Q9UDF8|uniprotkb:B4DNT0|ensembl:ENSP00000370115.5	intact:EBI-2814961|uniprotkb:Q81U91|uniprotkb:Q6I2H7|uniprotkb:Q6KWA5|uniprotkb:E9R3G5|uniprotkb:E9R3G6|uniprotkb:E9R3G7|uniprotkb:A0A1J9W7Z9|uniprotkb:A0A6L8PRF2	psi-mi:ileu_human(display_long)|uniprotkb:SERPINB1(gene name)|psi-mi:SERPINB1(display_short)|uniprotkb:ELANH2(gene name synonym)|uniprotkb:MNEI(gene name synonym)|uniprotkb:PI2(gene name synonym)|uniprotkb:Monocyte/neutrophil elastase inhibitor(gene name synonym)|uniprotkb:Peptidase inhibitor 2(gene name synonym)|uniprotkb:Serpin B1(gene name synonym)	psi-mi:q9k5j5_bacan(display_long)|uniprotkb:GBAA_0993(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831534|imex:IM-13779-3545	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011512635.1|refseq:XP_011512636.1|refseq:NP_109591.1|ensembl:ENSG00000021355.13(gene)|ensembl:ENST00000380739.6(transcript)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005769""(early endosome)|go:""GO:0010951""(negative regulation of endopeptidase activity)|go:""GO:0016020""(membrane)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030414""(peptidase inhibitor activity)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0044194""(cytolytic granule)|go:""GO:0044342""(type B pancreatic cell proliferation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:4GA7|reactome:R-HSA-6798695|panther:PTHR11461(orthology-group)"	"interpro:IPR009040(Ferritin-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR008331(Ferritin and Dps)|rcsb pdb:2QQY|go:""GO:0004322""(ferroxidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006880""(obsolete intracellular sequestering of iron ion)|go:""GO:0008199""(ferric iron binding)|go:""GO:0020037""(heme binding)|refseq:WP_000017764.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5IolAmA+BrS4XHZZEQgf05kA4pE9606	rogid:W2fLmWtCEAVCVzcMbdBz7iQAWpI1392	intact-crc:899E0A98A65E7EE5|rigid:zqAF+zlS55U+cSd0WX7Qc4SKU3g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3P1UEP4	uniprotkb:P27930	intact:EBI-2831563|uniprotkb:Q6KMQ0|uniprotkb:Q6HTF7|uniprotkb:E9R6G6|uniprotkb:E9R6G7|uniprotkb:Q81M05|uniprotkb:A0A1J9VHT5	intact:EBI-2831568|uniprotkb:Q9UE68|uniprotkb:D3DVJ5|uniprotkb:Q6LCE6|ensembl:ENSP00000330959.3|ensembl:ENSP00000377066.2	psi-mi:a0a3p1uep4_bacan(display_long)|uniprotkb:GBAA_4450(locus name)	psi-mi:il1r2_human(display_long)|uniprotkb:IL1R2(gene name)|psi-mi:IL1R2(display_short)|uniprotkb:IL1RB(gene name synonym)|uniprotkb:CD121 antigen-like family member B(gene name synonym)|uniprotkb:CDw121b(gene name synonym)|uniprotkb:Interleukin-1 receptor beta(gene name synonym)|uniprotkb:Interleukin-1 receptor type II(gene name synonym)|uniprotkb:IL-1 type II receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831560|imex:IM-13779-3546	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR038718|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000330(SNF2-related)|interpro:IPR027417|refseq:WP_001100021.1|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)|interpro:IPR049730"	"refseq:XP_011510106.1|refseq:NP_004624.1|refseq:NP_001248348.1|refseq:XP_006712797.1|ensembl:ENSG00000115590.14(gene)|ensembl:ENST00000332549.8(transcript)|ensembl:ENST00000393414.6(transcript)|go:""GO:0004908""(interleukin-1 receptor activity)|go:""GO:0004910""(interleukin-1, type II, blocking receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009986""(cell surface)|go:""GO:0010955""(negative regulation of protein processing)|go:""GO:0016485""(protein processing)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0032690""(negative regulation of interleukin-1 alpha production)|go:""GO:1900016""(negative regulation of cytokine production involved in inflammatory response)|go:""GO:2000660""(negative regulation of interleukin-1-mediated signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR004074(Interleukin-1 receptor, type I and type II)|interpro:IPR004077(Interleukin-1 receptor, type II)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR036179|mint:P27930|rcsb pdb:3O4O|reactome:R-HSA-6783783|reactome:R-HSA-9020702|dip:DIP-61267N|panther:PTHR11890(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:phA09Jei35YCJ2QGMwfXIr68+Kk1392	rogid:dbXLqsJM7HjQKDnuuUlyGcwp/Tc9606	intact-crc:3DB1FF5CE00B09CB|rigid:V5APMBxBvTrFvXht7+7BPRwBO2o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HJC6	uniprotkb:Q9UKT9	intact:EBI-2820663|uniprotkb:Q6HZ80|uniprotkb:Q6KT73|uniprotkb:E9QZP4|uniprotkb:E9QZP5|uniprotkb:Q81R09|uniprotkb:A0A1S0QN45|uniprotkb:A0A2P0HDW8	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|ensembl:ENSP00000344544.3|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5	psi-mi:a0a6l7hjc6_bacan(display_long)|uniprotkb:GBAA_2251(locus name)|uniprotkb:asnO3(gene name)|psi-mi:asnO3(display_short)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831608|imex:IM-13779-3552	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR001962(Asparagine synthase)|interpro:IPR017932|interpro:IPR033738|interpro:IPR029055|go:""GO:0004066""(""asparagine synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006529""(asparagine biosynthetic process)|interpro:IPR051786|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:WP_000333816.1"	"ensembl:ENSG00000161405.18(gene)|ensembl:ENST00000346872.8(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007498""(mesoderm development)|go:""GO:0009617""(response to bacterium)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030888""(regulation of B cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045619""(regulation of lymphocyte differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:1990841""(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050589|mint:Q9UKT9|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_001271445.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|efo:""Orphanet:67038""|dip:DIP-56975N|panther:PTHR24404(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WTdgXI+311I0qC/oeld/7wVHnps1392	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:8652B0354351438F|rigid:2ivxaRSXHuli9GdIK73RMMYvu2o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81NT0	uniprotkb:Q14005	intact:EBI-2828783|uniprotkb:Q6HX00|uniprotkb:Q6KR32	intact:EBI-2831580|uniprotkb:A8MU65|uniprotkb:B9EGR6|uniprotkb:Q6ZMQ7|uniprotkb:Q9UP18|uniprotkb:A6NM20|uniprotkb:Q16435|uniprotkb:Q6VVE6|uniprotkb:B5TY35|uniprotkb:H3BVH5|ensembl:ENSP00000508085.1|intact:EBI-28973443	"psi-mi:pxpa_bacan(display_long)|uniprotkb:pxpA(gene name)|psi-mi:pxpA(display_short)|uniprotkb:""5-oxoprolinase (ATP-hydrolyzing) subunit A""(gene name synonym)|uniprotkb:BAS2880(locus name)|uniprotkb:BA_3095(locus name)|uniprotkb:GBAA_3095(locus name)"	psi-mi:il16_human(display_long)|uniprotkb:IL16(gene name)|psi-mi:IL16(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831601|imex:IM-13779-3549	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR005501(LamB/YcsF)|refseq:WP_000207358.1|go:""GO:0005524""(ATP binding)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0017168""(""5-oxoprolinase (ATP-hydrolyzing) activity"")|refseq:NP_845422.1|refseq:YP_029138.1"	"refseq:XP_011519822.1|refseq:NP_001165599.1|refseq:NP_004504.3|refseq:NP_757366.2|refseq:XP_005254403.1|refseq:XP_016877630.1|refseq:XP_016877631.1|ensembl:ENSG00000172349.19(gene)|ensembl:ENST00000683961.1(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006955""(immune response)|go:""GO:0016607""(nuclear speck)|go:""GO:0030595""(leukocyte chemotaxis)|go:""GO:0032730""(positive regulation of interleukin-1 alpha production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050930""(induction of positive chemotaxis)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0090543""(Flemming body)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|interpro:IPR055287|mint:Q14005|rcsb pdb:1I16|rcsb pdb:1X6D|rcsb pdb:5FB8|reactome:R-HSA-449836|dip:DIP-6006N|panther:PTHR48396(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xuyh2Z/yhJ6Eq1PjIpOJosyxLFs1392	rogid:3kcSA6a4uuNCcII2VNJRIVUGY+89606	intact-crc:0E67D22D656810CD|rigid:ldZnPXvqDVxVb2UrwbQnrM63cxY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2B6CAK8	uniprotkb:Q14005	intact:EBI-2831592|uniprotkb:Q6I217|uniprotkb:Q6KVV4|uniprotkb:E9QUW7|uniprotkb:E9QUW8|uniprotkb:Q81TT3|uniprotkb:A0A0J1I2J8|uniprotkb:A0A2B8ISM2	intact:EBI-2831580|uniprotkb:A8MU65|uniprotkb:B9EGR6|uniprotkb:Q6ZMQ7|uniprotkb:Q9UP18|uniprotkb:A6NM20|uniprotkb:Q16435|uniprotkb:Q6VVE6|uniprotkb:B5TY35|uniprotkb:H3BVH5|ensembl:ENSP00000508085.1|intact:EBI-28973443	psi-mi:a0a2b6cak8_bacan(display_long)|uniprotkb:GBAA_1178(locus name)	psi-mi:il16_human(display_long)|uniprotkb:IL16(gene name)|psi-mi:IL16(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831577|imex:IM-13779-3553	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021324|refseq:WP_001211116.1|go:""GO:0016020""(membrane)"	"refseq:XP_011519822.1|refseq:NP_001165599.1|refseq:NP_004504.3|refseq:NP_757366.2|refseq:XP_005254403.1|refseq:XP_016877630.1|refseq:XP_016877631.1|ensembl:ENSG00000172349.19(gene)|ensembl:ENST00000683961.1(transcript)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006955""(immune response)|go:""GO:0016607""(nuclear speck)|go:""GO:0030595""(leukocyte chemotaxis)|go:""GO:0032730""(positive regulation of interleukin-1 alpha production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050930""(induction of positive chemotaxis)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0090543""(Flemming body)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|interpro:IPR055287|mint:Q14005|rcsb pdb:1I16|rcsb pdb:1X6D|rcsb pdb:5FB8|reactome:R-HSA-449836|dip:DIP-6006N|panther:PTHR48396(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:m5QdWh7MISWrRAo5A5Kn/cYG5eQ1392	rogid:3kcSA6a4uuNCcII2VNJRIVUGY+89606	intact-crc:87C2BC4F4646A73D|rigid:pbEF9cryZ2ZkQVxecrMNjswCI4w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13422	uniprotkb:A0A6L8PLB2	intact:EBI-745305|uniprotkb:O00598|uniprotkb:Q8WVA3|uniprotkb:Q53XL2|uniprotkb:B4E0Z1|uniprotkb:A4D260|uniprotkb:D3DVM5|uniprotkb:Q69BM4|intact:EBI-28969803|ensembl:ENSP00000331614.3	intact:EBI-2831618|uniprotkb:Q6KXE1|uniprotkb:Q6I3M9|uniprotkb:E9QST2|uniprotkb:E9QST3|uniprotkb:Q81YS7|uniprotkb:A0A0F7RMG0	psi-mi:ikzf1_human(display_long)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:a0a6l8plb2_bacan(display_long)|uniprotkb:Microbial collagenase(gene name synonym)|uniprotkb:GBAA_0555(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831615|imex:IM-13779-3550	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:317473""|efo:""Orphanet:36426""|efo:""Orphanet:585909""|dip:DIP-41110N|ensembl:ENSG00000185811.21(gene)|ensembl:ENST00000331340.8(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005721""(pericentric heterochromatin)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007498""(mesoderm development)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030098""(lymphocyte differentiation)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050589|mint:Q13422|rcsb pdb:6H0F|rcsb pdb:8D7Z|rcsb pdb:8D80|rcsb pdb:8RQC|rcsb pdb:8TNP|rcsb pdb:8TNQ|rcsb pdb:8TNR|reactome:R-HSA-9013508|refseq:NP_001207694.1|refseq:NP_001207696.1|refseq:NP_001207697.1|refseq:NP_001207699.1|refseq:NP_001207700.1|refseq:NP_001278766.1|refseq:NP_001278767.1|refseq:NP_001278768.1|refseq:NP_001278769.1|refseq:NP_001278770.1|refseq:NP_001278771.1|refseq:NP_001278772.1|refseq:NP_001278773.1|refseq:NP_006051.1|refseq:XP_011513370.1|refseq:XP_011513371.1|refseq:XP_011513377.1|refseq:XP_011513378.1|refseq:XP_016867157.1|panther:PTHR24404(orthology-group)"	"interpro:IPR041379|interpro:IPR007280(Peptidase, archaeal and bacterial C-terminal)|interpro:IPR002169(Peptidase M9A/M9B, microbial collagenase)|interpro:IPR013661(Peptidase M9A/M9B, N-terminal)|interpro:IPR022409|interpro:IPR000601(PKD)|refseq:WP_001036378.1|rcsb pdb:5SV5|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035986"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:RizH0uz3DbSyFFvmlIhisx+S+DI9606	rogid:UM0tIHF5sK1ZVxsgsw/1Q5ZlEFQ1392	intact-crc:31A0D2FE59B97706|rigid:u085d/YNccFi8+sHiXQFYySRRQE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15111	uniprotkb:A0A6L7HK67	intact:EBI-81249|uniprotkb:O14666|uniprotkb:Q13132|uniprotkb:Q5W0I4|uniprotkb:Q92467|ensembl:ENSP00000359424.6|intact:EBI-28970970	intact:EBI-2815211|uniprotkb:Q6KS75|uniprotkb:Q6HY61|uniprotkb:E9QQN8|uniprotkb:E9QQN9|uniprotkb:Q81PZ1|uniprotkb:A0A0F7RDJ0	psi-mi:ikka_human(display_long)|uniprotkb:CHUK(gene name)|psi-mi:CHUK(display_short)|uniprotkb:IKKA(gene name synonym)|uniprotkb:TCF16(gene name synonym)|uniprotkb:I-kappa-B kinase 1(gene name synonym)|uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym)|uniprotkb:Transcription factor 16(gene name synonym)	psi-mi:a0a6l7hk67_bacan(display_long)|uniprotkb:GBAA_2648(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831627|imex:IM-13779-3551	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000213341.11(gene)|ensembl:ENST00000370397.8(transcript)|go:""GO:0003009""(skeletal muscle contraction)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008384""(IkappaB kinase activity)|go:""GO:0008385""(IkappaB kinase complex)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009615""(response to virus)|go:""GO:0009636""(response to toxic substance)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010034""(response to acetate)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0033194""(response to hydroperoxide)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0038061""(non-canonical NF-kappaB signal transduction)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043200""(response to amino acid)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051146""(striated muscle cell differentiation)|go:""GO:0061847""(response to cholecystokinin)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0097110""(scaffold protein binding)|go:""GO:0098586""(cellular response to virus)|go:""GO:1990459""(transferrin receptor binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022007|interpro:IPR041185|interpro:IPR046375|interpro:IPR051180|mint:O15111|rcsb pdb:3BRT|rcsb pdb:5EBZ|rcsb pdb:5TQW|rcsb pdb:5TQX|rcsb pdb:5TQY|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-198323|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5674400|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9705671|reactome:R-HSA-975144|reactome:R-HSA-9758274|reactome:R-HSA-9833482|reactome:R-HSA-9860276|reactome:R-HSA-9860927|refseq:NP_001269.3|panther:PTHR22969(orthology-group)|efo:""Orphanet:465824""|dip:DIP-27526N"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005543(PASTA)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR050515|go:""GO:0005886""(plasma membrane)|go:""GO:0008658""(penicillin binding)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|refseq:WP_000549348.1|interpro:IPR036138"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:FVB/gXjSBTB9hdq9pycQogxesms9606	rogid:ebZgkIx4kdtUxCYHTTIW/f29OTU1392	intact-crc:83505684F8418269|rigid:DH96cOfq+FvL2bokhKmHIkssZxs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:A0A6L8PF45	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2831641|uniprotkb:Q6HRU1|uniprotkb:Q6KL49|uniprotkb:E9QWT9|uniprotkb:E9QWU0|uniprotkb:Q81KD6|uniprotkb:A0A0F7RAL5	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:a0a6l8pf45_bacan(display_long)|uniprotkb:feoB(gene name)|psi-mi:feoB(display_short)|uniprotkb:GBAA_5064(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831647|imex:IM-13779-3557	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"interpro:IPR041069|interpro:IPR003373(Ferrous iron transport protein B)|interpro:IPR011640(Ferrous iron transport B, C-terminal)|interpro:IPR011642(Nucleoside recognition)|interpro:IPR006073(GTP1/OBG)|refseq:WP_001044820.1|interpro:IPR027417|interpro:IPR030389|go:""GO:0005525""(GTP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015093""(ferrous iron transmembrane transporter activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR050860"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:9jQwZ4i974wMzbx5LReh2SXlhWE1392	intact-crc:0D4C1399F8C58B6C|rigid:xBhARtZvonl2txMqvDwJakqdRb0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:A0A6L8PQC3	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2811440|uniprotkb:Q6I444|uniprotkb:Q6KXV4|uniprotkb:E9QQR3|uniprotkb:E9QQR4|uniprotkb:A0A2P0H9A7|uniprotkb:Q81ZA2	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:a0a6l8pqc3_bacan(display_long)|uniprotkb:GBAA_0370(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831654|imex:IM-13779-3555	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|refseq:WP_000410216.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:+ivfvCodXbxbEMok2GCUbqdVQA01392	intact-crc:0FF750C4073E46F3|rigid:KO12B7/FjU1uyPb0pTsWf+26BU4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:A0A0F7REH3	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2811064|uniprotkb:Q6KPV8|uniprotkb:E9R093|uniprotkb:Q81YE8	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:a0a0f7reh3_bacan(display_long)|uniprotkb:GBAA_3601(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831661|imex:IM-13779-3556	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	refseq:WP_001116379.1|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:kRV2TrznOHMKW2jOg5FKoFx9L+41392	intact-crc:8F55B84072023B6B|rigid:mahyWIWogHd5SHAYe1VSMY22O9E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:Q81X85	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2812174|uniprotkb:Q6KKE0|uniprotkb:E9RAE3	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:q81x85_bacan(display_long)|uniprotkb:GBAA_5357(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831668|imex:IM-13779-3558	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"interpro:IPR002711(HNH endonuclease)|interpro:IPR003615(HNH nuclease)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0008270""(zinc ion binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:cvrrKkEnADjyuk0XbSWnTXpzR/01392	intact-crc:E29D4237047CD2B3|rigid:9c1/ngO3p5biLPkyl4NLoKUGplo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:Q81R83	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2810574|uniprotkb:Q6KTE5|uniprotkb:Q6HZF6	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:y2173_bacan(display_long)|uniprotkb:BA_2173(locus name)|uniprotkb:GBAA_2173(locus name)|uniprotkb:BAS2019(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831634|imex:IM-13779-3554	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"interpro:IPR009474(Protein of unknown function DUF1094)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_000063712.1|refseq:NP_844566.1|refseq:YP_028282.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:DwG1RQbAdj088ZOY9O74UrEBXms1392	intact-crc:D3CC283705B6D3FA|rigid:7m03yGe4icbGn3uSxolQam7qhe8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HCN1	uniprotkb:Q9P2H3	intact:EBI-2819428|uniprotkb:Q6KR15|uniprotkb:Q6HWY3|uniprotkb:E9RE22|uniprotkb:E9RE23|uniprotkb:Q81NR3|uniprotkb:A0A0F7RFT3	intact:EBI-2831704|uniprotkb:Q86YF4|uniprotkb:B4E0K1|uniprotkb:Q3MJC4|uniprotkb:Q9UIX1|uniprotkb:C9J8I0|ensembl:ENSP00000312778.7	psi-mi:a0a6l7hcn1_bacan(display_long)|uniprotkb:GBAA_3114(locus name)	psi-mi:ift80_human(display_long)|uniprotkb:IFT80(gene name)|psi-mi:IFT80(display_short)|uniprotkb:KIAA1374(gene name synonym)|uniprotkb:WDR56(gene name synonym)|uniprotkb:WD repeat-containing protein 56(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831701|imex:IM-13779-3562	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR022703|go:""GO:0005886""(plasma membrane)|refseq:WP_000475892.1|interpro:IPR051328"	"efo:""Orphanet:474""|efo:""Orphanet:93268""|efo:""Orphanet:93271""|ensembl:ENSG00000068885.15(gene)|ensembl:ENST00000326448.12(transcript)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001958""(endochondral ossification)|go:""GO:0003418""(growth plate cartilage chondrocyte differentiation)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005929""(cilium)|go:""GO:0006915""(apoptotic process)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0010467""(gene expression)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0010839""(negative regulation of keratinocyte proliferation)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0021510""(spinal cord development)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030992""(intraciliary transport particle B)|go:""GO:0033687""(osteoblast proliferation)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035567""(non-canonical Wnt signaling pathway)|go:""GO:0035630""(bone mineralization involved in bone maturation)|go:""GO:0035720""(intraciliary anterograde transport)|go:""GO:0036064""(ciliary basal body)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0043616""(keratinocyte proliferation)|go:""GO:0044691""(tooth eruption)|go:""GO:0048863""(stem cell differentiation)|go:""GO:0050821""(protein stabilization)|go:""GO:0060173""(limb development)|go:""GO:0060271""(cilium assembly)|go:""GO:0061975""(articular cartilage development)|go:""GO:0071895""(odontoblast differentiation)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0097500""(receptor localization to non-motile cilium)|go:""GO:0097542""(ciliary tip)|go:""GO:0097731""(9+0 non-motile cilium)|go:""GO:1902140""(response to inositol)|go:""GO:1905515""(non-motile cilium assembly)|go:""GO:1990079""(cartilage homeostasis)|go:""GO:2000051""(negative regulation of non-canonical Wnt signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9P2H3|reactome:R-HSA-5620924|refseq:NP_001177170.1|refseq:NP_001177171.1|refseq:NP_065851.1|panther:PTHR24098(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/ALX/fZorB6SbLvparnF57FTVm01392	rogid:mwOhWzHklTm/JMbs3fxLbB0TV/w9606	intact-crc:FE8CB4DD5AD34D79|rigid:CdCSkly/+kCOxi4Q4DeqVDk+nU8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:A0A6H3A6B3	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2831675|uniprotkb:Q6KWY6|uniprotkb:Q6I366|uniprotkb:E9QYB3|uniprotkb:E9QYB4|uniprotkb:Q81UY5|uniprotkb:A0A1J9VER5	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:a0a6h3a6b3_bacan(display_long)|uniprotkb:GBAA_0721(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831680|imex:IM-13779-3561	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	interpro:IPR025046|interpro:IPR025087|refseq:WP_000648923.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:WQfxOgLoTZqDBFlWSaTF6KX0RGQ1392	intact-crc:51BF7AF73EE775FE|rigid:2DXTGOL0qFN1n3mm/C0rTGdHp4k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01857	uniprotkb:A0A6L8P3I2	intact:EBI-356114|ensembl:ENSP00000374990.2|ensembl:ENSP00000487867.1|intact:EBI-25626819|uniprotkb:A0A0A0MS08	intact:EBI-2811571|uniprotkb:A0A1Q4M2S2|uniprotkb:Q6I206|uniprotkb:Q6KVU4|uniprotkb:E9RAG4|uniprotkb:E9RAG5|uniprotkb:Q81TS3|uniprotkb:A0A2A7DD91	psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym)	psi-mi:a0a6l8p3i2_bacan(display_long)|uniprotkb:GBAA_1192(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831687|imex:IM-13779-3559	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:536""|efo:""Orphanet:67038""|ensembl:ENSG00000211896.7(gene)|ensembl:ENSG00000277633.5(gene)|ensembl:ENST00000390548.6(transcript)|ensembl:ENST00000631539.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071735""(IgG immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|go:""GO:0097278""(complement-dependent cytotoxicity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1I7Z|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:3WJL|rcsb pdb:3WKN|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5C7K|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|rcsb pdb:7LUR|rcsb pdb:7Q15|rcsb pdb:7Q3P|rcsb pdb:7WSO|rcsb pdb:8DIN|rcsb pdb:8DIR|rcsb pdb:8DJ7|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|panther:PTHR23411(orthology-group)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|refseq:WP_000534165.1|interpro:IPR035906|interpro:IPR045621"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/28	rogid:32CYg2KdiKeP3GHprY6p2xeg60M9606	rogid:SXL75EkM2v0JzmCCHwl3FIhC4W81392	intact-crc:56D46AB44D728BBC|rigid:89DwYBk2vCyeWv31SC52jT1DDoY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AKA7	uniprotkb:P01877	intact:EBI-2820788|uniprotkb:Q6KRR3|uniprotkb:Q6HXN9|uniprotkb:E9QTQ1|uniprotkb:E9QTQ2|uniprotkb:Q81PH4|uniprotkb:A0A1Q4LYX8	intact:EBI-1044357|uniprotkb:A0A075B6N7|uniprotkb:A0A286YEY5|ensembl:ENSP00000493086.1	psi-mi:a0a6h3aka7_bacan(display_long)|uniprotkb:GBAA_2831(locus name)	psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831694|imex:IM-13779-3560	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|refseq:WP_000958324.1|interpro:IPR029510|go:""GO:0016620""(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)"	"ensembl:ENSG00000211890.4(gene)|ensembl:ENST00000497872.4(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0003094""(glomerular filtration)|go:""GO:0003823""(antigen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0006958""(complement activation, classical pathway)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0042571""(immunoglobulin complex, circulating)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060267""(positive regulation of respiratory burst)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071745""(IgA immunoglobulin complex)|go:""GO:0071748""(monomeric IgA immunoglobulin complex)|go:""GO:0071751""(secretory IgA immunoglobulin complex)|go:""GO:0071752""(secretory dimeric IgA immunoglobulin complex)|go:""GO:0072562""(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|panther:PTHR23411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RzeKhc5uMxcN17JUK2WtBIBhVDc1392	rogid:qIM2Dw0MV/9ufvUyHGhx7fQ2qgY9606	intact-crc:EDE08D070B7654BF|rigid:GRYk0M2atngQ0Db3wMTq7H0gLPA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01629	uniprotkb:A0A6L8NXZ3	intact:EBI-373124|uniprotkb:Q96DA8|uniprotkb:Q6FH82|ensembl:ENSP00000484689.1|ensembl:ENSP00000505840.1	intact:EBI-2819190|uniprotkb:Q6KTM9|uniprotkb:Q6HZP2|uniprotkb:E9RBA8|uniprotkb:E9RBA9|uniprotkb:Q81RG7|uniprotkb:A0A0F7RIY3	psi-mi:ifm2_human(display_long)|uniprotkb:IFITM2(gene name)|psi-mi:IFITM2(display_short)|uniprotkb:Interferon-inducible protein 1-8D(gene name synonym)|uniprotkb:Dispanin subfamily A member 2c(gene name synonym)	psi-mi:a0a6l8nxz3_bacan(display_long)|uniprotkb:GBAA_2080(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831723|imex:IM-13779-3563	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENST00000616316.3(transcript)|refseq:NP_006426.2|ensembl:ENST00000680197.1(transcript)|ensembl:ENSG00000185201.18(gene)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009615""(response to virus)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035455""(response to interferon-alpha)|go:""GO:0035456""(response to interferon-beta)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|interpro:IPR051517|reactome:R-HSA-909733|panther:PTHR13999(orthology-group)"	"interpro:IPR029063|go:""GO:0008168""(methyltransferase activity)|go:""GO:0032259""(methylation)|refseq:WP_000038486.1|interpro:IPR041698"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tuhid+OEGpPbsGE2dFHG5owwbsE9606	rogid:7AiIbFHJlC9H8VMhT9G4QzCGxY41392	intact-crc:BF32718E34E6FCB5|rigid:dZKJ5sGB7Ks6LeHzfhpuw2MDqBA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40305	uniprotkb:A0A6H3ABE4	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	intact:EBI-2831752|uniprotkb:Q6KJM3|uniprotkb:Q6HQ89|uniprotkb:E9QWB6|uniprotkb:E9QWB7|uniprotkb:Q81JP3|uniprotkb:A0A1Q4LWR1	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	psi-mi:a0a6h3abe4_bacan(display_long)|uniprotkb:GBAA_5659(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831749|imex:IM-13779-3565	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:WP_000868713.1|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR050397|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	rogid:gpYDu2wKK3yH6GB/cep130zijmg1392	intact-crc:06010CF11B406D1D|rigid:Ajr8TXA2x1Eq+EuAwYxT9EuTTvU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:P40305	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831742|imex:IM-13779-3564	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	intact-crc:CC56D42699F20BAC|rigid:tgGhF/gKxyR9jIzkR1f2rA1pKv4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PX73	uniprotkb:Q8IY31	intact:EBI-2814460|uniprotkb:Q6HTD2|uniprotkb:Q6KMM4|uniprotkb:E9R6D4|uniprotkb:E9R6D5|uniprotkb:Q81LY0|uniprotkb:A0A0J1HYA4	intact:EBI-744203|uniprotkb:Q5GLZ2|uniprotkb:Q9BUG5|intact:EBI-2561300|uniprotkb:J3QL09|ensembl:ENSP00000378809.3|ensembl:ENSP00000463138.1	psi-mi:a0a6l8px73_bacan(display_long)|uniprotkb:GBAA_4479(locus name)	psi-mi:ift20_human(display_long)|uniprotkb:IFT20(gene name)|psi-mi:IFT20(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831716|imex:IM-13779-3567	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003171(Methylenetetrahydrofolate reductase)|interpro:IPR003726(Homocysteine S-methyltransferase)|interpro:IPR050554|interpro:IPR029041|go:""GO:0004489""(""methylenetetrahydrofolate reductase (NAD(P)H) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0008705""(methionine synthase activity)|go:""GO:0032259""(methylation)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|refseq:WP_000770331.1|interpro:IPR036589"	"refseq:NP_001254706.1|refseq:NP_001254707.1|refseq:NP_777547.1|refseq:NP_001254703.1|refseq:NP_001254704.1|refseq:NP_001254705.1|ensembl:ENSG00000109083.14(gene)|ensembl:ENST00000395418.8(transcript)|ensembl:ENST00000585313.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0001736""(establishment of planar polarity)|go:""GO:0001750""(photoreceptor outer segment)|go:""GO:0001822""(kidney development)|go:""GO:0002046""(opsin binding)|go:""GO:0002177""(manchette)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005814""(centriole)|go:""GO:0005902""(microvillus)|go:""GO:0005929""(cilium)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008542""(visual learning)|go:""GO:0030990""(intraciliary transport particle)|go:""GO:0030992""(intraciliary transport particle B)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031514""(motile cilium)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0032420""(stereocilium)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0035720""(intraciliary anterograde transport)|go:""GO:0035845""(photoreceptor cell outer segment organization)|go:""GO:0036064""(ciliary basal body)|go:""GO:0036372""(opsin transport)|go:""GO:0043005""(neuron projection)|go:""GO:0044292""(dendrite terminus)|go:""GO:0045198""(establishment of epithelial cell apical/basal polarity)|go:""GO:0045724""(positive regulation of cilium assembly)|go:""GO:0051642""(centrosome localization)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060122""(inner ear receptor cell stereocilium organization)|go:""GO:0060271""(cilium assembly)|go:""GO:0060828""(regulation of canonical Wnt signaling pathway)|go:""GO:0061351""(neural precursor cell proliferation)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090102""(cochlea development)|go:""GO:0097542""(ciliary tip)|go:""GO:0097546""(ciliary base)|go:""GO:0097730""(non-motile cilium)|go:""GO:1902017""(regulation of cilium assembly)|go:""GO:1902636""(kinociliary basal body)|go:""GO:2000583""(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR028172|mint:Q8IY31|reactome:R-HSA-5620924|panther:PTHR31978(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kwYps3uM+vfuLmFjfNZe8XCRW/U1392	rogid:/sGgagcq0b/YoxjD4Psc7D6jY2Q9606	intact-crc:A745172A5694C3B4|rigid:yiwx3g9N10wAYvXzioJ/1sAonts	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TCB0	uniprotkb:Q81TB4	intact:EBI-2831730|uniprotkb:Q14496|uniprotkb:D3DQ80|uniprotkb:B7ZAG3|ensembl:ENSP00000359783.4	intact:EBI-2818482|uniprotkb:Q6KVE2|uniprotkb:Q4A4I6|uniprotkb:Q6I1J1|uniprotkb:E9QYH5|uniprotkb:E9QYH6|uniprotkb:E9QYH7|uniprotkb:A0A2A8KL91|uniprotkb:A0A348A175|uniprotkb:A0A6L8PXC7	psi-mi:ifi44_human(display_long)|uniprotkb:IFI44(gene name)|psi-mi:IFI44(display_short)|uniprotkb:MTAP44(gene name synonym)|uniprotkb:Microtubule-associated protein 44(gene name synonym)	psi-mi:q81tb4_bacan(display_long)|uniprotkb:nrdF(gene name)|psi-mi:nrdF(display_short)|uniprotkb:GBAA_1372(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831735|imex:IM-13779-3566	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006408.3|ensembl:ENSG00000137965.11(gene)|ensembl:ENST00000370747.9(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0006955""(immune response)|go:""GO:0009615""(response to virus)|go:""GO:0009617""(response to bacterium)|interpro:IPR006571(TLDc)|interpro:IPR027417|panther:PTHR14241(orthology-group)"	"interpro:IPR030475|refseq:WP_001203038.1|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR026494|go:""GO:0004748""(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:""GO:0005971""(ribonucleoside-diphosphate reductase complex)|go:""GO:0009263""(deoxyribonucleotide biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR033909|interpro:IPR012348(Ribonucleotide reductase-related)|rcsb pdb:6TQV|rcsb pdb:6TQW|rcsb pdb:6TQX|rcsb pdb:6TQY|rcsb pdb:6TQZ|rcsb pdb:6QO5|rcsb pdb:6QO7|rcsb pdb:6QO8|rcsb pdb:6QO9|rcsb pdb:6QOB"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8WC3TPSpHflhjOOQwwmw6wM0+G89606	rogid:uzZy2ZE+v5dKX/96PuFAlTIyWXM1392	intact-crc:7C51DC965791CA28|rigid:RwepgMqGK5AgQrCKpY7eWRBuprY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P23588	uniprotkb:A0A6L8PC29	intact:EBI-970310|ensembl:ENSP00000262056.9|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13	intact:EBI-2810801|uniprotkb:Q6KRM4|uniprotkb:Q6HXJ8|uniprotkb:E9QRE3|uniprotkb:E9QRE4|uniprotkb:A0A2P0HF49|uniprotkb:Q81PD4	psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short)	psi-mi:a0a6l8pc29_bacan(display_long)|uniprotkb:GBAA_2876(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831802|imex:IM-13779-3570	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000063046.18(gene)|ensembl:ENST00000262056.14(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865|refseq:NP_001408.2|refseq:NP_001317583.1|panther:PTHR23236(orthology-group)"	refseq:WP_001062740.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606	rogid:4BbTj8554Gwm4rVypGL1Pva9DGE1392	intact-crc:D33E1563E2DE681D|rigid:JzvQ5D4fsnL5JGKwBZBxaFxHXqk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63241	uniprotkb:Q81UZ6	intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776.8|ensembl:ENSP00000390677.2|ensembl:ENSP00000396073.2|ensembl:ENSP00000458269.1|ensembl:ENSP00000459196.1|ensembl:ENSP00000459611.1|ensembl:ENSP00000499855.1|ensembl:ENSP00000499995.1|ensembl:ENSP00000500414.1|ensembl:ENSP00000500624.1|ensembl:ENSP00000500717.1|ensembl:ENSP00000500847.1	intact:EBI-2831778|uniprotkb:Q6I378|uniprotkb:Q6KWZ7|uniprotkb:E9RBG7|uniprotkb:E9RBG8|uniprotkb:A0A2P0HA71	psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym)	psi-mi:q81uz6_bacan(display_long)|uniprotkb:gerLA(gene name)|psi-mi:gerLA(display_short)|uniprotkb:GBAA_0709(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831775|imex:IM-13779-3569	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:528084""|ensembl:ENSG00000132507.18(gene)|ensembl:ENSG00000288145.1(gene)|ensembl:ENST00000336458.13(transcript)|ensembl:ENST00000416016.2(transcript)|ensembl:ENST00000419711.6(transcript)|ensembl:ENST00000571955.5(transcript)|ensembl:ENST00000573542.5(transcript)|ensembl:ENST00000576930.5(transcript)|ensembl:ENST00000672250.1(transcript)|ensembl:ENST00000672755.1(transcript)|ensembl:ENST00000673099.1(transcript)|ensembl:ENST00000673210.1(transcript)|ensembl:ENST00000673259.1(transcript)|ensembl:ENST00000673304.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005642""(annulate lamellae)|go:""GO:0005643""(nuclear pore)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0043022""(ribosome binding)|go:""GO:0045901""(positive regulation of translational elongation)|go:""GO:0045905""(positive regulation of translational termination)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0098586""(cellular response to virus)|go:""GO:1902255""(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884(""Eukaryotic initiation factor 5A hypusine (eIF-5A)"")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|interpro:IPR048670|mint:P63241|rcsb pdb:3CPF|rcsb pdb:5DLQ|rcsb pdb:8A0E|rcsb pdb:8Y0W|reactome:R-HSA-204626|refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|panther:PTHR11673(orthology-group)"	"interpro:IPR004995(Bacillus/Clostridium GerA spore germination protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0009847""(spore germination)|interpro:IPR050768"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606	rogid:j7mARNLOwAKGtb494NabwvK5u/s1392	intact-crc:4E5C7E8149EA209E|rigid:SXRoyJsLobX1JLLvvzEftJTYZas	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40305	uniprotkb:A0A6L7HB40	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	intact:EBI-2812761|uniprotkb:Q6I3J5|uniprotkb:Q6KXA8|uniprotkb:E9R2F8|uniprotkb:E9R2F9|uniprotkb:A0A2P0H9V3|uniprotkb:Q81VA8	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	psi-mi:a0a6l7hb40_bacan(display_long)|uniprotkb:GBAA_0589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831768|imex:IM-13779-3571	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR001041(Ferredoxin)|interpro:IPR006478(Formate dehydrogenase, alpha subunit)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR019574|interpro:IPR050123|interpro:IPR027467|go:""GO:0003954""(NADH dehydrogenase activity)|go:""GO:0008863""(""formate dehydrogenase (NAD+) activity"")|go:""GO:0015942""(formate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_000840648.1|interpro:IPR036010|interpro:IPR041924"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	rogid:QNDnbGYfnNxnQEMZtqgLWO6/cVs1392	intact-crc:6EEC5C9301B283F6|rigid:Td5gOU7GWOjEpegu2UoxJdT4ebU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3P1TZI9	uniprotkb:O43432	intact:EBI-2823766|uniprotkb:Q6KL71|uniprotkb:Q6HRW7|uniprotkb:E9RBZ0|uniprotkb:E9RBZ1|uniprotkb:Q81KG1|uniprotkb:A0A1T3V3K0	intact:EBI-464766|uniprotkb:Q5SWC3|uniprotkb:Q15597|uniprotkb:Q8NEN1|uniprotkb:Q504Z1|uniprotkb:B9EGQ7|ensembl:ENSP00000264211.7	psi-mi:a0a3p1tzi9_bacan(display_long)|uniprotkb:GBAA_5038(locus name)	psi-mi:if4g3_human(display_long)|uniprotkb:EIF4G3(gene name)|psi-mi:EIF4G3(display_short)|uniprotkb:eIF-4-gamma II(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831795|imex:IM-13779-3573	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|refseq:WP_000368781.1|interpro:IPR035906"	"refseq:NP_001185732.1|refseq:NP_003751.2|refseq:NP_001185731.1|refseq:NP_001185730.1|panther:PTHR23253(orthology-group)|ensembl:ENSG00000075151.24(gene)|ensembl:ENST00000264211.13(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0007286""(spermatid development)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0045727""(positive regulation of translation)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016024(Armadillo-type fold)|mint:O43432|rcsb pdb:1HU3|reactome:R-HSA-1169408|refseq:XP_016858189.1|refseq:XP_016858197.1|refseq:XP_016858201.1|dip:DIP-33245N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BLmyeOGpG6dFbqPB5wG5ZmCRmY41392	rogid:dN5046U5kz1WfBJD0+NWYMMU6RY9606	intact-crc:F55CB559D0CA2B12|rigid:ZC9zGVbVrX3Rrr/PJDygk5czN00	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40305	uniprotkb:A0A6L7HHX2	intact:EBI-2805952|uniprotkb:A0A087WZF8|uniprotkb:A8K0H0|uniprotkb:Q7Z5R0|uniprotkb:Q7Z5R1|uniprotkb:Q7Z5R2|uniprotkb:Q9H4B1|uniprotkb:Q96BK3|uniprotkb:Q53YA6|uniprotkb:Q6IEC1|ensembl:ENSP00000477753.1|ensembl:ENSP00000483430.1|ensembl:ENSP00000483498.1|ensembl:ENSP00000483932.1|ensembl:ENSP00000484089.1|ensembl:ENSP00000486608.1	intact:EBI-2812285|uniprotkb:Q6KUB0|uniprotkb:Q6I0E0|uniprotkb:E9QSI8|uniprotkb:E9QSI9|uniprotkb:Q81S59|uniprotkb:A0A0F7RKM4	psi-mi:ifi27_human(display_long)|uniprotkb:Interferon alpha-induced 11.5 kDa protein(gene name synonym)|uniprotkb:Interferon-stimulated gene 12a protein(gene name synonym)|uniprotkb:IFI27(gene name)|psi-mi:IFI27(display_short)	psi-mi:a0a6l7hhx2_bacan(display_long)|uniprotkb:GBAA_1815(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831761|imex:IM-13779-3568	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001275888.1|refseq:NP_001275889.1|refseq:NP_001123552.1|refseq:NP_005523.3|refseq:NP_001275881.1|refseq:NP_001275883.1|refseq:NP_001275885.1|refseq:NP_001275886.1|refseq:NP_001275887.1|refseq:NP_001275924.1|ensembl:ENSG00000165949.13(gene)|ensembl:ENSG00000275214.4(gene)|ensembl:ENST00000612813.4(transcript)|ensembl:ENST00000612838.4(transcript)|ensembl:ENST00000613997.4(transcript)|ensembl:ENST00000616764.5(transcript)|ensembl:ENST00000621160.5(transcript)|ensembl:ENST00000627111.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001836""(release of cytochrome c from mitochondria)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044827""(modulation by host of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0046825""(regulation of protein export from nucleus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097193""(intrinsic apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213|reactome:R-HSA-909733|panther:PTHR16932(orthology-group)"	"interpro:IPR025450|go:""GO:0016020""(membrane)|refseq:WP_000789548.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uqCEU/1pSKtFLk1ZtDmLuuPJFhI9606	rogid:g0iSNc7Mh4tgNaBj+nHYsEjH5sY1392	intact-crc:D6A7E2B08CCFB771|rigid:4j/0iB17Yp0wRUm6YTs5Ll0Wsa8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15056	uniprotkb:A0A6L7H7R4	intact:EBI-748492|uniprotkb:A8K3R1|uniprotkb:D3DXF6|uniprotkb:D3DXF8|ensembl:ENSP00000265753.8	intact:EBI-2814598|uniprotkb:Q6I1X0|uniprotkb:Q6KVR2|uniprotkb:E9RAJ8|uniprotkb:E9RAJ9|uniprotkb:Q81TN9|uniprotkb:A0A1S0QL17	psi-mi:if4h_human(display_long)|uniprotkb:Williams-Beuren syndrome chromosomal region 1 protein(gene name synonym)|uniprotkb:EIF4H(gene name)|psi-mi:EIF4H(display_short)|uniprotkb:WBSCR1(gene name synonym)|uniprotkb:KIAA0038(gene name synonym)|uniprotkb:WSCR1(gene name synonym)	psi-mi:a0a6l7h7r4_bacan(display_long)|uniprotkb:GBAA_1231(locus name)|uniprotkb:rfbD(gene name)|psi-mi:rfbD(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831788|imex:IM-13779-3572	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106682.16(gene)|ensembl:ENST00000265753.13(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0016020""(membrane)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0019953""(sexual reproduction)|go:""GO:0045296""(cadherin binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048589""(developmental growth)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034229|interpro:IPR035979|mint:Q15056|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_071496.1|refseq:NP_114381.1|efo:""Orphanet:904""|panther:PTHR23236(orthology-group)"	"interpro:IPR005913(dTDP-4-dehydrorhamnose reductase)|rcsb pdb:3SC6|go:""GO:0000166""(nucleotide binding)|go:""GO:0005829""(cytosol)|go:""GO:0008831""(dTDP-4-dehydrorhamnose reductase activity)|go:""GO:0019305""(dTDP-rhamnose biosynthetic process)|go:""GO:0045226""(obsolete extracellular polysaccharide biosynthetic process)|refseq:WP_000664670.1|interpro:IPR029903|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dNPoAzwFD5lFwCMnRl0cbXM3j8s9606	rogid:TGeZ8RAjVc+Mul2hbC3OCTywlmI1392	intact-crc:E30785656CEFF420|rigid:WMmXUkYxGnxDVv4IP9+ky34RPYw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P60842	uniprotkb:A0A4Y1WE58	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831.8	intact:EBI-2810305|uniprotkb:Q6KW20|uniprotkb:Q6I285|uniprotkb:E9R1F6|uniprotkb:E9R1F7|uniprotkb:A0A2P0HB60|uniprotkb:Q81U00	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:a0a4y1we58_bacan(display_long)|uniprotkb:GBAA_1094(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831816|imex:IM-13779-3576	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001407.1|panther:PTHR24031(orthology-group)|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960.16(gene)|ensembl:ENST00000293831.13(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097165""(nuclear stress granule)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|rcsb pdb:7PPZ|rcsb pdb:7PQ0|rcsb pdb:8HUJ|rcsb pdb:8OZ0|rcsb pdb:8XXN|rcsb pdb:9AVR|rcsb pdb:9BLN|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865"	"interpro:IPR020968|interpro:IPR008979(Galactose-binding like)|interpro:IPR022385|interpro:IPR006530(YD repeat)|interpro:IPR050708|go:""GO:0016020""(membrane)|refseq:WP_000387561.1|interpro:IPR045351|interpro:IPR031325"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	rogid:8jqYn7kracNCDGYibTeEcZe2fl81392	intact-crc:9FBF8A21E0F97EA4|rigid:C0zKHDu7mhLQnwx/mpuYG5I0FKE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14240	uniprotkb:Q81P27	intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381.5	intact:EBI-2814639|uniprotkb:Q6KRC1|uniprotkb:Q6HX99	psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:proa_bacan(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:BA_2992(locus name)|uniprotkb:GBAA_2992(locus name)|uniprotkb:BAS2781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831809|imex:IM-13779-3574	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24031(orthology-group)|efo:""Orphanet:528084""|ensembl:ENSG00000156976.17(gene)|ensembl:ENST00000323963.10(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1900260""(negative regulation of RNA-dependent RNA polymerase activity)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865|refseq:NP_001958.2"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|go:""GO:0004350""(glutamate-5-semialdehyde dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0050661""(NADP binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:NP_845325.1|refseq:YP_029039.1|refseq:WP_001006638.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/30	rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606	rogid:2iR76/3cLX7gyVDMLNG2KEyBoMY1392	intact-crc:35B1BBDA019EE93F|rigid:ubKkIc/x/74Vl+7DEqCiQHzZG6U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KV7	uniprotkb:P60842	intact:EBI-2819109|uniprotkb:Q6KLK9|uniprotkb:Q6HSB3	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831.8	psi-mi:assy_bacan(display_long)|uniprotkb:argG(gene name)|psi-mi:argG(display_short)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:BA_4880(locus name)|uniprotkb:GBAA_4880(locus name)|uniprotkb:BAS4528(locus name)	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831823|imex:IM-13779-3577	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|go:""GO:0000050""(urea cycle)|go:""GO:0000053""(argininosuccinate metabolic process)|go:""GO:0004055""(argininosuccinate synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|refseq:WP_000412328.1|refseq:NP_847081.1|refseq:YP_030775.1|interpro:IPR048267|interpro:IPR048268"	"refseq:NP_001407.1|panther:PTHR24031(orthology-group)|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960.16(gene)|ensembl:ENST00000293831.13(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097165""(nuclear stress granule)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|rcsb pdb:7PPZ|rcsb pdb:7PQ0|rcsb pdb:8HUJ|rcsb pdb:8OZ0|rcsb pdb:8XXN|rcsb pdb:9AVR|rcsb pdb:9BLN|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:5ecBR1qj/ajGIxCdyzTMfvl1+tA1392	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	intact-crc:17732A153F356E14|rigid:spWbwZZV1kqFxYUB4tWgXzh2XT0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HBJ1	uniprotkb:Q14240	intact:EBI-2831830|uniprotkb:Q6KTU5|uniprotkb:Q6HZW3|uniprotkb:E9QWC4|uniprotkb:E9QWC5|uniprotkb:Q81RN9|uniprotkb:A0A1Q4M155	intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381.5	psi-mi:a0a6l7hbj1_bacan(display_long)|uniprotkb:GBAA_2003(locus name)	psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831842|imex:IM-13779-3575	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020471|interpro:IPR023210|refseq:WP_000877936.1|go:""GO:0005829""(cytosol)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR036812|interpro:IPR050523"	"panther:PTHR24031(orthology-group)|efo:""Orphanet:528084""|ensembl:ENSG00000156976.17(gene)|ensembl:ENST00000323963.10(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1900260""(negative regulation of RNA-dependent RNA polymerase activity)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865|refseq:NP_001958.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/30	rogid:trq8KyUFA/VA3LlcUo6y1p28AuA1392	rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606	intact-crc:D353731E6DD63245|rigid:rKr7MNCz8/2dwv4zGx4R4RSq/RE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50213	uniprotkb:Q81K85	intact:EBI-355999|uniprotkb:D3DW83|uniprotkb:Q9H3X0|ensembl:ENSP00000299518.2	intact:EBI-2812720|uniprotkb:Q6KL02|uniprotkb:Q6HRN6	"psi-mi:idh3a_human(display_long)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:""NAD(+)-specific ICDH subunit alpha""(gene name synonym)"	psi-mi:glga_bacan(display_long)|uniprotkb:glgA(gene name)|psi-mi:glgA(display_short)|uniprotkb:Starch [bacterial glycogen] synthase(gene name synonym)|uniprotkb:BA_5120(locus name)|uniprotkb:GBAA_5120(locus name)|uniprotkb:BAS4758(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831882|imex:IM-13779-3583	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:791""|ensembl:ENSG00000166411.14(gene)|ensembl:ENST00000299518.7(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004449""(""isocitrate dehydrogenase (NAD+) activity"")|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006102""(isocitrate metabolic process)|go:""GO:0045242""(""isocitrate dehydrogenase complex (NAD+)"")|go:""GO:0051287""(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P50213|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|rcsb pdb:8GRB|rcsb pdb:8GRD|rcsb pdb:8GRG|rcsb pdb:8GRH|rcsb pdb:8GRU|rcsb pdb:8GS5|reactome:R-HSA-71403|reactome:R-HSA-9837999|refseq:NP_005521.1|panther:PTHR11835(orthology-group)"	"interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR011835(Glycogen/starch synthases, ADP-glucose type)|interpro:IPR013534(Starch synthase catalytic region)|go:""GO:0004373""(""alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"")|go:""GO:0005978""(glycogen biosynthetic process)|go:""GO:0009011""(""alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity"")|refseq:WP_011053260.1|refseq:NP_847306.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JvAUAMJ0DcgnIfvy/vlfRyXYzhE9606	rogid:uWEjM8noLfVuOuXNS3DfnaCdS3I1392	intact-crc:84E998B1D078E55B|rigid:hZ6TRjlaSDUHh7stTDcQV+7YeXQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20042	uniprotkb:A0A6L8PTK5	intact:EBI-711977|uniprotkb:Q9BVU0|uniprotkb:Q9UJE4|ensembl:ENSP00000364119.2	intact:EBI-2815740|uniprotkb:Q6KLC6|uniprotkb:Q6HS22|uniprotkb:E9R820|uniprotkb:E9R821|uniprotkb:Q81KM0|uniprotkb:A0A0F7R5G6	psi-mi:if2b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit beta(gene name synonym)|uniprotkb:EIF2S2(gene name)|psi-mi:EIF2S2(display_short)|uniprotkb:EIF2B(gene name synonym)	psi-mi:a0a6l8ptk5_bacan(display_long)|uniprotkb:GBAA_4976(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831875|imex:IM-13779-3582	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000125977.7(gene)|ensembl:ENST00000374980.3(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001731""(formation of translation preinitiation complex)|go:""GO:0002176""(male germ cell proliferation)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005850""(eukaryotic translation initiation factor 2 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0008584""(male gonad development)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|interpro:IPR045196|mint:P20042|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|rcsb pdb:7QP6|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PPL|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|reactome:R-HSA-9833482|reactome:R-HSA-9840373|refseq:NP_003899.2|panther:PTHR23001(orthology-group)"	"interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0008146""(sulfotransferase activity)|go:""GO:0008641""(ubiquitin-like modifier activating enzyme activity)|go:""GO:0016779""(nucleotidyltransferase activity)|refseq:WP_001158094.1|interpro:IPR035985|interpro:IPR045886"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:64ZkCKZ5jRT6MEm9RK4AynY2ga49606	rogid:uDGO+gtg3zkc7kwxZa3vzDK2sII1392	intact-crc:608F2676D3AD2413|rigid:IGKSx4vO4MCGi/H4VFt8W1ePNqo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PUD2	uniprotkb:P54105	intact:EBI-2831889|uniprotkb:Q6KKT4|uniprotkb:Q6HRG7|uniprotkb:E9RA46|uniprotkb:E9RA47|uniprotkb:Q81XP0|uniprotkb:A0A0F7RBJ7	intact:EBI-724693|uniprotkb:Q0VDK6|uniprotkb:Q9NRD2|uniprotkb:Q9NRD3|uniprotkb:B2RCS9|ensembl:ENSP00000433919.1|ensembl:ENSP00000434311.1	psi-mi:a0a6l8pud2_bacan(display_long)|uniprotkb:GBAA_5193(locus name)	psi-mi:icln_human(display_long)|uniprotkb:Chloride conductance regulatory protein ICln(gene name synonym)|uniprotkb:Chloride channel, nucleotide sensitive 1A(gene name synonym)|uniprotkb:Chloride ion current inducer protein(gene name synonym)|uniprotkb:Reticulocyte pICln(gene name synonym)|uniprotkb:CLNS1A(gene name)|psi-mi:CLNS1A(display_short)|uniprotkb:ICLN(gene name synonym)|uniprotkb:CLCI(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831894|imex:IM-13779-3580	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001845(Bacterial regulatory protein, ArsR)|interpro:IPR001034(Bacterial regulatory protein, DeoR N-terminal)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:WP_000503330.1|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR050313|interpro:IPR036388|interpro:IPR036390|interpro:IPR041359"	"refseq:NP_001284.1|refseq:NP_001298128.1|refseq:NP_001298129.1|refseq:NP_001298130.1|refseq:NP_001298131.1|ensembl:ENSG00000074201.9(gene)|ensembl:ENST00000525428.6(transcript)|ensembl:ENST00000528364.1(transcript)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006821""(chloride transport)|go:""GO:0006884""(cell volume homeostasis)|go:""GO:0034709""(methylosome)|go:""GO:0034715""(pICln-Sm protein complex)|go:""GO:0045292""(mRNA cis splicing, via spliceosome)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR003521(Nucleotide-sensitive chloride conductance regulator)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039924|mint:P54105|rcsb pdb:6V0O|reactome:R-HSA-191859|dip:DIP-44185N|panther:PTHR21399(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/25	rogid:cTXP9If0LlJzoB+QlgAF+YBiZPU1392	rogid:dGx9UwPj9VBp1CiPTRCXnT3IYt89606	intact-crc:F07C16E40D14D396|rigid:rE2dw8bi/psA7vRZwq67jZ6H23s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P60842	uniprotkb:A0A6L7HB40	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831.8	intact:EBI-2812761|uniprotkb:Q6I3J5|uniprotkb:Q6KXA8|uniprotkb:E9R2F8|uniprotkb:E9R2F9|uniprotkb:A0A2P0H9V3|uniprotkb:Q81VA8	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:a0a6l7hb40_bacan(display_long)|uniprotkb:GBAA_0589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831849|imex:IM-13779-3578	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001407.1|panther:PTHR24031(orthology-group)|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960.16(gene)|ensembl:ENST00000293831.13(transcript)|go:""GO:0000339""(RNA cap binding)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016020""(membrane)|go:""GO:0016281""(eukaryotic translation initiation factor 4F complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097165""(nuclear stress granule)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|rcsb pdb:7PPZ|rcsb pdb:7PQ0|rcsb pdb:8HUJ|rcsb pdb:8OZ0|rcsb pdb:8XXN|rcsb pdb:9AVR|rcsb pdb:9BLN|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9820841|reactome:R-HSA-9820865"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR001041(Ferredoxin)|interpro:IPR006478(Formate dehydrogenase, alpha subunit)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR019574|interpro:IPR050123|interpro:IPR027467|go:""GO:0003954""(NADH dehydrogenase activity)|go:""GO:0008863""(""formate dehydrogenase (NAD+) activity"")|go:""GO:0015942""(formate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_000840648.1|interpro:IPR036010|interpro:IPR041924"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	rogid:QNDnbGYfnNxnQEMZtqgLWO6/cVs1392	intact-crc:E6808B14794D50A6|rigid:j7WGXa4dKuiIYBlfXfr+gmemeRE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P20042	uniprotkb:A0A6L8PBD5	intact:EBI-711977|uniprotkb:Q9BVU0|uniprotkb:Q9UJE4|ensembl:ENSP00000364119.2	intact:EBI-2829672|uniprotkb:Q6I2M5|uniprotkb:Q6KWF6|uniprotkb:E9QXR4|uniprotkb:E9QXR5|uniprotkb:Q81UE4|uniprotkb:A0A0F7RLM5	psi-mi:if2b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit beta(gene name synonym)|uniprotkb:EIF2S2(gene name)|psi-mi:EIF2S2(display_short)|uniprotkb:EIF2B(gene name synonym)	psi-mi:a0a6l8pbd5_bacan(display_long)|uniprotkb:GBAA_0933(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831868|imex:IM-13779-3579	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000125977.7(gene)|ensembl:ENST00000374980.3(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001731""(formation of translation preinitiation complex)|go:""GO:0002176""(male germ cell proliferation)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005850""(eukaryotic translation initiation factor 2 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0008584""(male gonad development)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0045202""(synapse)|go:""GO:0046872""(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|interpro:IPR045196|mint:P20042|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|rcsb pdb:7QP6|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PPL|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|reactome:R-HSA-9833482|reactome:R-HSA-9840373|refseq:NP_003899.2|panther:PTHR23001(orthology-group)"	interpro:IPR006343(DnaD and phage-associated region)|interpro:IPR034829|refseq:WP_000312068.1|interpro:IPR053162	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:64ZkCKZ5jRT6MEm9RK4AynY2ga49606	rogid:zaPwWMNfIORViTxNL4kLO80PqEo1392	intact-crc:9602BAC2E983302A|rigid:k0jRgMUUN7Z3YbFs25NjbkcBNrw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1WFX8	uniprotkb:P46199	intact:EBI-2831856|uniprotkb:Q6KX03|uniprotkb:E9RDN2|uniprotkb:Q81V02	intact:EBI-359432|uniprotkb:D6W5D0|ensembl:ENSP00000263629.4|ensembl:ENSP00000378099.3|ensembl:ENSP00000384481.1	psi-mi:a0a4y1wfx8_bacan(display_long)|uniprotkb:qoxB(gene name)|psi-mi:qoxB(display_short)|uniprotkb:GBAA_0702(locus name)	psi-mi:if2m_human(display_long)|uniprotkb:MTIF2(gene name)|psi-mi:MTIF2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831861|imex:IM-13779-3581	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014233(Cytochrome aa3 quinol oxidase, subunit I)|interpro:IPR000883(Cytochrome c oxidase, subunit I)|interpro:IPR023615|interpro:IPR023616|refseq:WP_000762372.1|go:""GO:0004129""(cytochrome-c oxidase activity)|go:""GO:0005507""(copper ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0015990""(electron transport coupled proton transport)|go:""GO:0016682""(oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor)|go:""GO:0020037""(heme binding)|go:""GO:0022904""(respiratory electron transport chain)|interpro:IPR036927"	"refseq:NP_001307933.1|refseq:NP_001307934.1|refseq:NP_001005369.1|refseq:NP_002444.2|refseq:NP_001307930.1|refseq:NP_001307931.1|refseq:NP_001307932.1|refseq:XP_005264392.1|ensembl:ENSG00000085760.15(gene)|ensembl:ENST00000263629.9(transcript)|ensembl:ENST00000394600.7(transcript)|ensembl:ENST00000403721.5(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0008135""(translation factor activity, RNA binding)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0043024""(ribosomal small subunit binding)|go:""GO:0070124""(mitochondrial translational initiation)|interpro:IPR000178(Initiation factor 2)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR023115|interpro:IPR027417|interpro:IPR036925|interpro:IPR044145|interpro:IPR053905|mint:P46199|rcsb pdb:6GAW|rcsb pdb:6GAZ|rcsb pdb:6GB2|rcsb pdb:6RW5|rcsb pdb:7PO2|rcsb pdb:8QRN|reactome:R-HSA-5368286|refseq:XP_011531173.1|refseq:XP_016859651.1|refseq:XP_016859652.1|dip:DIP-27596N|panther:PTHR43381(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GkQcmjxQrwaNgkTGbhY5HgCJOwo1392	rogid:ThigwWzs0gInoPjmmd8DYvyrWw49606	intact-crc:A9E4DBAE2B076248|rigid:A/LgEEMhtp7Gxw+2niMmIH2Ifgo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PZS0	uniprotkb:Q16270	intact:EBI-2831915|uniprotkb:Q6KLT8|uniprotkb:Q6HSJ3|uniprotkb:E9QRT9|uniprotkb:E9QRU0|uniprotkb:A0A2P0HJH5|uniprotkb:Q81L39	intact:EBI-2831923|uniprotkb:Q07822|uniprotkb:Q53YE6|uniprotkb:Q9UCA8|uniprotkb:B4E1N2|uniprotkb:B7Z9W7|ensembl:ENSP00000295666.4	psi-mi:a0a6l8pzs0_bacan(display_long)|uniprotkb:GBAA_4795(locus name)	psi-mi:ibp7_human(display_long)|uniprotkb:IGFBP7(gene name)|psi-mi:IGFBP7(display_short)|uniprotkb:MAC25(gene name synonym)|uniprotkb:PSF(gene name synonym)|uniprotkb:IGFBP-rP1(gene name synonym)|uniprotkb:MAC25 protein(gene name synonym)|uniprotkb:PGI2-stimulating factor(gene name synonym)|uniprotkb:Prostacyclin-stimulating factor(gene name synonym)|uniprotkb:Tumor-derived adhesion factor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831920|imex:IM-13779-3587	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029398|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR022311|interpro:IPR047967|refseq:WP_000867530.1|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042578""(phosphoric ester hydrolase activity)|interpro:IPR027421|interpro:IPR037160|interpro:IPR043519|interpro:IPR050243"	"efo:""Orphanet:284247""|ensembl:ENSG00000163453.11(gene)|ensembl:ENST00000295666.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005520""(insulin-like growth factor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007155""(cell adhesion)|go:""GO:0007566""(embryo implantation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050810""(regulation of steroid biosynthetic process)|go:""GO:0051414""(response to cortisol)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011390(""Insulin-like growth factor binding protein related protein (IGFBP-rP), MAC25"")|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036058|interpro:IPR036179|mint:Q16270|rcsb pdb:8IVD|reactome:R-HSA-2559582|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001240764.1|refseq:NP_001544.1|panther:PTHR14186(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eadaVC645BZc9HjE8igO54X7Ea81392	rogid:t1eeHgPHn1Mxu+9sloOIuPoBBRo9606	intact-crc:526F770C5A0495AB|rigid:ZzcrmXlJjuYCLjMMEnhm6T2Na54	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16270	uniprotkb:A0A6L7HC63	intact:EBI-2831923|uniprotkb:Q07822|uniprotkb:Q53YE6|uniprotkb:Q9UCA8|uniprotkb:B4E1N2|uniprotkb:B7Z9W7|ensembl:ENSP00000295666.4	intact:EBI-2811370|uniprotkb:Q6KTZ3|uniprotkb:Q6I014|uniprotkb:E9QYA2|uniprotkb:E9QYA3|uniprotkb:Q81RT7|uniprotkb:A0A0F7RJ72	psi-mi:ibp7_human(display_long)|uniprotkb:IGFBP7(gene name)|psi-mi:IGFBP7(display_short)|uniprotkb:MAC25(gene name synonym)|uniprotkb:PSF(gene name synonym)|uniprotkb:IGFBP-rP1(gene name synonym)|uniprotkb:MAC25 protein(gene name synonym)|uniprotkb:PGI2-stimulating factor(gene name synonym)|uniprotkb:Prostacyclin-stimulating factor(gene name synonym)|uniprotkb:Tumor-derived adhesion factor(gene name synonym)	psi-mi:a0a6l7hc63_bacan(display_long)|uniprotkb:GBAA_1950(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831934|imex:IM-13779-3585	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:284247""|ensembl:ENSG00000163453.11(gene)|ensembl:ENST00000295666.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005520""(insulin-like growth factor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007155""(cell adhesion)|go:""GO:0007566""(embryo implantation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050810""(regulation of steroid biosynthetic process)|go:""GO:0051414""(response to cortisol)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011390(""Insulin-like growth factor binding protein related protein (IGFBP-rP), MAC25"")|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036058|interpro:IPR036179|mint:Q16270|rcsb pdb:8IVD|reactome:R-HSA-2559582|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001240764.1|refseq:NP_001544.1|panther:PTHR14186(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR018044|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0071555""(cell wall organization)|refseq:WP_000825873.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t1eeHgPHn1Mxu+9sloOIuPoBBRo9606	rogid:C+GkPog4qlTLKuFTOFPtKPvk7yQ1392	intact-crc:FE23C1705568191B|rigid:CBKdoeogvoY9FCIIMzQAkN9C/zQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1WE58	uniprotkb:Q05084	intact:EBI-2810305|uniprotkb:Q6KW20|uniprotkb:Q6I285|uniprotkb:E9R1F6|uniprotkb:E9R1F7|uniprotkb:A0A2P0HB60|uniprotkb:Q81U00	intact:EBI-1046751|uniprotkb:P78506|uniprotkb:Q13824|uniprotkb:A8K7U1|uniprotkb:B3FTQ2|ensembl:ENSP00000379908.3|ensembl:ENSP00000385570.3|ensembl:ENSP00000385651.2|intact:EBI-3915169|uniprotkb:Q96HG3	psi-mi:a0a4y1we58_bacan(display_long)|uniprotkb:GBAA_1094(locus name)	psi-mi:ica69_human(display_long)|uniprotkb:69 kDa islet cell autoantigen(gene name synonym)|uniprotkb:Islet cell autoantigen p69(gene name synonym)|uniprotkb:ICA1(gene name)|psi-mi:ICA1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831901|imex:IM-13779-3584	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020968|interpro:IPR008979(Galactose-binding like)|interpro:IPR022385|interpro:IPR006530(YD repeat)|interpro:IPR050708|go:""GO:0016020""(membrane)|refseq:WP_000387561.1|interpro:IPR045351|interpro:IPR031325"	"refseq:NP_001129492.1|refseq:NP_004959.2|refseq:NP_071682.1|ensembl:ENSG00000003147.19(gene)|ensembl:ENST00000396675.7(transcript)|ensembl:ENST00000402384.8(transcript)|ensembl:ENST00000406470.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006836""(neurotransmitter transport)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030672""(synaptic vesicle membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0051049""(regulation of transport)|go:""GO:0140090""(membrane curvature sensor activity)|interpro:IPR006723(Islet cell autoantigen ICA69 homologue)|interpro:IPR010504(Arfaptin-like)|interpro:IPR024114|interpro:IPR027267|mint:Q05084|refseq:NP_001263407.1|refseq:XP_005249792.1|refseq:XP_011513647.1|refseq:XP_011513648.1|refseq:XP_011513649.1|refseq:XP_011513650.1|refseq:XP_011513651.1|refseq:XP_016867606.1|refseq:XP_016867607.1|refseq:XP_016867608.1|refseq:XP_016867609.1|refseq:XP_016867610.1|panther:PTHR10164(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8jqYn7kracNCDGYibTeEcZe2fl81392	rogid:pVUULpiv0K4iNKkaK448C2ubSDo9606	intact-crc:22A205390566BD32|rigid:Tq7zkNe3jRQg2IRGGNyHGdFFFEQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P2D0	uniprotkb:Q81LC7	intact:EBI-1052017|uniprotkb:Q2QKU2|uniprotkb:Q2QKU3|uniprotkb:Q2QKU4|uniprotkb:Q5TFD7|uniprotkb:Q5TFD9|uniprotkb:Q8IUQ9|uniprotkb:Q8IUY7|uniprotkb:Q8TAI4|uniprotkb:Q9HBI8|uniprotkb:Q9Y3T8|ensembl:ENSP00000305721.7|ensembl:ENSP00000489389.1	intact:EBI-2812814|uniprotkb:Q6HST0|uniprotkb:Q6KM23	psi-mi:ibtk_human(display_long)|uniprotkb:IBTK(gene name)|psi-mi:IBTK(display_short)|uniprotkb:BTKI(gene name synonym)|uniprotkb:KIAA1417(gene name synonym)	psi-mi:hem3_bacan(display_long)|uniprotkb:hemC(gene name)|psi-mi:hemC(display_short)|uniprotkb:Hydroxymethylbilane synthase(gene name synonym)|uniprotkb:Pre-uroporphyrinogen synthase(gene name synonym)|uniprotkb:BA_4696(locus name)|uniprotkb:GBAA_4696(locus name)|uniprotkb:BAS4361(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831908|imex:IM-13779-3586	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056340.2|refseq:NP_001287835.1|ensembl:ENSG00000005700.15(gene)|ensembl:ENSG00000283068.2(gene)|ensembl:ENST00000306270.12(transcript)|ensembl:ENST00000635454.2(transcript)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0016020""(membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR002110(Ankyrin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR051625|mint:Q9P2D0|panther:PTHR22872(orthology-group)"	"interpro:IPR000860(Tetrapyrrole biosynthesis, hydroxymethylbilane synthase)|interpro:IPR022419|interpro:IPR022417|interpro:IPR022418|go:""GO:0004418""(hydroxymethylbilane synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|refseq:WP_001226429.1|interpro:IPR036803|refseq:NP_846909.1|refseq:YP_030608.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cP+4mOtwZi3q2AjApgwpcJRpJ6M9606	rogid:5SdSplutrz20cjJc3QRlM+lx+XM1392	intact-crc:B57EF6E9F37818C5|rigid:fHV4qLmGbQZJbWHzEYFD4Df5UU4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95998	uniprotkb:A0A6L8PXG9	intact:EBI-2831962|uniprotkb:B3KUZ0|uniprotkb:B7WPK4|uniprotkb:Q9NZA9|uniprotkb:Q9UBR7|uniprotkb:O95993|uniprotkb:O96027|ensembl:ENSP00000338723.5|ensembl:ENSP00000377306.4|ensembl:ENSP00000377308.4|ensembl:ENSP00000384212.1|ensembl:ENSP00000434376.1|ensembl:ENSP00000513973.1|ensembl:ENSP00000513974.1|ensembl:ENSP00000513975.1|ensembl:ENSP00000513976.1	intact:EBI-2812708|uniprotkb:Q6HQF8|uniprotkb:Q6KJT3|uniprotkb:E9R1P6|uniprotkb:E9R1P7|uniprotkb:A0A2P0HLL5|uniprotkb:Q81JV7	psi-mi:i18bp_human(display_long)|uniprotkb:IL18BP(gene name)|psi-mi:IL18BP(display_short)|uniprotkb:Tadekinig-alfa(gene name synonym)	psi-mi:a0a6l8pxg9_bacan(display_long)|uniprotkb:GBAA_5587(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831972|imex:IM-13779-3591	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001034748.1|refseq:NP_001034749.1|refseq:NP_001138527.1|refseq:NP_001138529.1|refseq:NP_005690.2|refseq:NP_766630.2|refseq:NP_766632.2|refseq:XP_016872548.1|refseq:XP_016872549.1|refseq:XP_016872550.1|refseq:XP_016872551.1|refseq:XP_016872552.1|ensembl:ENSG00000137496.19(gene)|ensembl:ENST00000337131.9(transcript)|ensembl:ENST00000393703.9(transcript)|ensembl:ENST00000393705.8(transcript)|ensembl:ENST00000404792.5(transcript)|ensembl:ENST00000534583.5(transcript)|ensembl:ENST00000698837.1(transcript)|ensembl:ENST00000698838.1(transcript)|ensembl:ENST00000698839.1(transcript)|ensembl:ENST00000698840.1(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0042007""(interleukin-18 binding)|go:""GO:0042088""(T-helper 1 type immune response)|go:""GO:0048019""(receptor antagonist activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071356""(cellular response to tumor necrosis factor)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR039681|interpro:IPR055139|rcsb pdb:7AL7|reactome:R-HSA-9008059|reactome:R-HSA-9012546|panther:PTHR14292(orthology-group)"	"interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|go:""GO:0003995""(acyl-CoA dehydrogenase activity)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_001011195.1|interpro:IPR036250|interpro:IPR037069|interpro:IPR046373"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zWElsXA+tVpk1EgN1wYsoool+9s9606	rogid:UDN2yqO3fuPBFDlPHhHQ6vmTriQ1392	intact-crc:0FD8D3EE34697270|rigid:F+nceb+hIMnX9tgqGINSuhzf7Sk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13651	uniprotkb:A0A6L7HRI8	intact:EBI-1031656|ensembl:ENSP00000227752.4|uniprotkb:B0YJ27|uniprotkb:A8K6I0	intact:EBI-2810366|uniprotkb:Q6F051	psi-mi:i10r1_human(display_long)|uniprotkb:IL10RA(gene name)|psi-mi:IL10RA(display_short)|uniprotkb:IL10R(gene name synonym)|uniprotkb:Interleukin-10 receptor subunit 1(gene name synonym)|uniprotkb:CDw210a(gene name synonym)	psi-mi:a0a6l7hri8_bacan(display_long)|uniprotkb:GBAA_pXO2_0034(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831979|imex:IM-13779-3589	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110324.12(gene)|ensembl:ENST00000227752.8(transcript)|go:""GO:0004920""(interleukin-10 receptor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019969""(interleukin-10 binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050807""(regulation of synapse organization)|go:""GO:0060729""(intestinal epithelial structure maintenance)|go:""GO:0070086""(ubiquitin-dependent endocytosis)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR050650|mint:Q13651|rcsb pdb:1J7V|rcsb pdb:1LQS|rcsb pdb:1Y6K|rcsb pdb:1Y6M|rcsb pdb:1Y6N|rcsb pdb:5IXI|rcsb pdb:6X93|reactome:R-HSA-6783783|reactome:R-HSA-9725371|refseq:NP_001549.2|efo:""Orphanet:238569""|dip:DIP-3512N|panther:PTHR20859(orthology-group)"	"go:""GO:0016020""(membrane)|refseq:WP_000249505.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sMAPIcNDOtzRHrmx79PMcP9jDRA9606	rogid:CttsAiL8z2LvYlOUlkIGYJ7cxoA1392	intact-crc:043245DA159A36CE|rigid:bkIUhod3ZJvmzeY4BTjThD7YZwE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PZS0	uniprotkb:P22692	intact:EBI-2831915|uniprotkb:Q6KLT8|uniprotkb:Q6HSJ3|uniprotkb:E9QRT9|uniprotkb:E9QRU0|uniprotkb:A0A2P0HJH5|uniprotkb:Q81L39	intact:EBI-2831948|uniprotkb:Q9UCL6|uniprotkb:Q5U012|uniprotkb:A0N9W2|uniprotkb:B4E351|ensembl:ENSP00000269593.4	psi-mi:a0a6l8pzs0_bacan(display_long)|uniprotkb:GBAA_4795(locus name)	psi-mi:ibp4_human(display_long)|uniprotkb:IGFBP4(gene name)|psi-mi:IGFBP4(display_short)|uniprotkb:IBP4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831955|imex:IM-13779-3590	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029398|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR022311|interpro:IPR047967|refseq:WP_000867530.1|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042578""(phosphoric ester hydrolase activity)|interpro:IPR027421|interpro:IPR037160|interpro:IPR043519|interpro:IPR050243"	"refseq:NP_001543.2|ensembl:ENSG00000141753.7(gene)|ensembl:ENST00000269593.5(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007165""(signal transduction)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0031994""(insulin-like growth factor I binding)|go:""GO:0031995""(insulin-like growth factor II binding)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043567""(regulation of insulin-like growth factor receptor signaling pathway)|go:""GO:0043568""(positive regulation of insulin-like growth factor receptor signaling pathway)|go:""GO:0044342""(type B pancreatic cell proliferation)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017891|interpro:IPR022321|interpro:IPR022327|interpro:IPR036857|mint:P22692|rcsb pdb:1WQJ|rcsb pdb:2DSP|rcsb pdb:2DSQ|rcsb pdb:2DSR|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-48432N|panther:PTHR11551(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/06	rogid:eadaVC645BZc9HjE8igO54X7Ea81392	rogid:Zwh1MoGM8TnKpAFBRG7tZoOBvr89606	intact-crc:681AA376D6185AD0|rigid:7m9Wfqq83QchoH6H7tvXJJGfLUE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7RJH9	uniprotkb:Q16270	intact:EBI-2819178|uniprotkb:Q6KUB8|uniprotkb:Q6I0F1|uniprotkb:E9QR02|uniprotkb:E9QR03|uniprotkb:Q81S69	intact:EBI-2831923|uniprotkb:Q07822|uniprotkb:Q53YE6|uniprotkb:Q9UCA8|uniprotkb:B4E1N2|uniprotkb:B7Z9W7|ensembl:ENSP00000295666.4	psi-mi:a0a0f7rjh9_bacan(display_long)|uniprotkb:GBAA_1802(locus name)	psi-mi:ibp7_human(display_long)|uniprotkb:IGFBP7(gene name)|psi-mi:IGFBP7(display_short)|uniprotkb:MAC25(gene name synonym)|uniprotkb:PSF(gene name synonym)|uniprotkb:IGFBP-rP1(gene name synonym)|uniprotkb:MAC25 protein(gene name synonym)|uniprotkb:PGI2-stimulating factor(gene name synonym)|uniprotkb:Prostacyclin-stimulating factor(gene name synonym)|uniprotkb:Tumor-derived adhesion factor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831941|imex:IM-13779-3588	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016020""(membrane)|interpro:IPR050980|interpro:IPR036890|refseq:WP_003161985.1"	"efo:""Orphanet:284247""|ensembl:ENSG00000163453.11(gene)|ensembl:ENST00000295666.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0005520""(insulin-like growth factor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007155""(cell adhesion)|go:""GO:0007566""(embryo implantation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009966""(regulation of signal transduction)|go:""GO:0032526""(response to retinoic acid)|go:""GO:0032870""(cellular response to hormone stimulus)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050810""(regulation of steroid biosynthetic process)|go:""GO:0051414""(response to cortisol)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011390(""Insulin-like growth factor binding protein related protein (IGFBP-rP), MAC25"")|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036058|interpro:IPR036179|mint:Q16270|rcsb pdb:8IVD|reactome:R-HSA-2559582|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001240764.1|refseq:NP_001544.1|panther:PTHR14186(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SFCM1iNTrKMxGz1erNTiU1HoM2A1392	rogid:t1eeHgPHn1Mxu+9sloOIuPoBBRo9606	intact-crc:2C08B99E6309C269|rigid:PdP/VP02RMGPsw3iRHLNgES0pkM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92743	uniprotkb:A0A6L7H9D5	intact:EBI-352256|uniprotkb:Q9UNS5|uniprotkb:D3DRE4|ensembl:ENSP00000357980.3	intact:EBI-2814246	psi-mi:htra1_human(display_long)|uniprotkb:HTRA1(gene name)|psi-mi:HTRA1(display_short)|uniprotkb:HTRA(gene name synonym)|uniprotkb:PRSS11(gene name synonym)|uniprotkb:High-temperature requirement A serine peptidase 1(gene name synonym)|uniprotkb:L56(gene name synonym)|uniprotkb:Serine protease 11(gene name synonym)	psi-mi:a0a6l7h9d5_bacan(display_long)|uniprotkb:BA_5677(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832014|imex:IM-13779-3596	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000166033.13(gene)|ensembl:ENST00000368984.8(transcript)|go:""GO:0001890""(placenta development)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0012501""(programmed cell death)|go:""GO:0019838""(growth factor binding)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030514""(negative regulation of BMP signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0060718""(chorionic trophoblast cell differentiation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140677""(molecular function activator activity)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR036034|interpro:IPR036058|interpro:IPR041489|mint:Q92743|rcsb pdb:2JOA|rcsb pdb:2YTW|rcsb pdb:3NUM|rcsb pdb:3NWU|rcsb pdb:3NZI|rcsb pdb:3TJN|rcsb pdb:3TJO|rcsb pdb:3TJQ|rcsb pdb:6Z0E|rcsb pdb:6Z0X|rcsb pdb:6Z0Y|rcsb pdb:7SJN|rcsb pdb:7SJO|rcsb pdb:7SJP|rcsb pdb:8SDM|rcsb pdb:8SDP|rcsb pdb:8SE7|rcsb pdb:8SE8|reactome:R-HSA-1474228|refseq:NP_002766.1|efo:""Orphanet:199354""|efo:""Orphanet:252128""|efo:""Orphanet:252212""|efo:""Orphanet:482077""|dip:DIP-33195N|panther:PTHR22939(orthology-group)"	"uniprotkb:Q81JM6(uniprot-removed-ac)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|refseq:NP_847824.2|refseq:WP_000672693.1|go:""GO:0016757""(glycosyltransferase activity)|interpro:IPR050834"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/07	rogid:Y7lT7nyI9N/3imHOz8Ng+Zagf509606	rogid:FwRCscVoC13GphL6UBpJVsxENgE1392	intact-crc:434B9697AFC04A47|rigid:81T+LARDrMQ+njDvyro/iW4zjt8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43464	uniprotkb:A0A6L7HE73	intact:EBI-517086|uniprotkb:Q9HBZ4|uniprotkb:Q9P0Y3|uniprotkb:Q9P0Y4|ensembl:ENSP00000258080.3	intact:EBI-2813877|uniprotkb:Q6HRP6|uniprotkb:Q6KL13|uniprotkb:E9QT89|uniprotkb:E9QT90|uniprotkb:Q81K96|uniprotkb:A0A0J1HS73|uniprotkb:A0A348ABD5	psi-mi:htra2_human(display_long)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)|uniprotkb:HTRA2(gene name)|psi-mi:HTRA2(display_short)|uniprotkb:PRSS25(gene name synonym)|uniprotkb:OMI(gene name synonym)	psi-mi:a0a6l7he73_bacan(display_long)|uniprotkb:menB(gene name)|psi-mi:menB(display_short)|uniprotkb:GBAA_5109(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832007|imex:IM-13779-3594	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2828""|efo:""Orphanet:505208""|ensembl:ENSG00000115317.13(gene)|ensembl:ENST00000258080.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006508""(proteolysis)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0007628""(adult walking behavior)|go:""GO:0008233""(peptidase activity)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0009635""(response to herbicide)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0012501""(programmed cell death)|go:""GO:0016020""(membrane)|go:""GO:0016540""(protein autoprocessing)|go:""GO:0019742""(pentacyclic triterpenoid metabolic process)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030291""(protein serine/threonine kinase inhibitor activity)|go:""GO:0030900""(forebrain development)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035458""(cellular response to interferon-beta)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0048666""(neuron development)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0071300""(cellular response to retinoic acid)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0097194""(execution phase of apoptosis)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|go:""GO:1905090""(negative regulation of type 2 mitophagy)|go:""GO:1905370""(serine-type endopeptidase complex)|go:""GO:1990948""(ubiquitin ligase inhibitor activity)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001241""(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:O43464|rcsb pdb:1LCY|rcsb pdb:2PZD|rcsb pdb:5FHT|rcsb pdb:5M3N|rcsb pdb:5M3O|rcsb pdb:5TNY|rcsb pdb:5TNZ|rcsb pdb:5TO0|rcsb pdb:5TO1|rcsb pdb:5WYN|rcsb pdb:7VGE|rcsb pdb:8AUK|rcsb pdb:8E2K|reactome:R-HSA-9837999|reactome:R-HSA-9841251|refseq:NP_001308656.1|refseq:NP_037379.1|refseq:NP_659540.1|panther:PTHR22939(orthology-group)"	"interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|interpro:IPR010198(Naphthoate synthase)|interpro:IPR029045|go:""GO:0005829""(cytosol)|go:""GO:0008935""(1,4-dihydroxy-2-naphthoyl-CoA synthase activity)|go:""GO:0009234""(menaquinone biosynthetic process)|refseq:WP_000963873.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IaLYfoH7H9K64U0KrEY7iB1vAfU9606	rogid:QcWu71AxxEE8Dr8cb9DlLXh7oEY1392	intact-crc:ED5DB9BBAE47A3B4|rigid:mmli3euaFvtWg06a+k0WJYATv3g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PBV3	uniprotkb:Q12891	intact:EBI-2824051|uniprotkb:Q6HQR8|uniprotkb:Q6KK36|uniprotkb:E9QZE9|uniprotkb:E9QZF0|uniprotkb:Q81WY2|uniprotkb:A0A0F7RAJ9	intact:EBI-2806068|uniprotkb:Q9BW29|uniprotkb:O15177|uniprotkb:B3KRZ2|ensembl:ENSP00000350387.4|ensembl:ENSP00000378571.3|ensembl:ENSP00000401853.1|ensembl:ENSP00000406657.1	psi-mi:a0a6l8pbv3_bacan(display_long)|uniprotkb:GBAA_5470(locus name)	psi-mi:hyal2_human(display_long)|uniprotkb:LUCA2(gene name synonym)|uniprotkb:Hyaluronoglucosaminidase-2(gene name synonym)|uniprotkb:Lung carcinoma protein 2(gene name synonym)|uniprotkb:HYAL2(gene name)|psi-mi:HYAL2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831993|imex:IM-13779-3595	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR012160(Membrane sulphatase, HI1246-related)|interpro:IPR000917(Sulphatase)|go:""GO:0005886""(plasma membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_000665364.1|interpro:IPR050448"	"ensembl:ENSG00000068001.14(gene)|ensembl:ENST00000357750.9(transcript)|ensembl:ENST00000395139.7(transcript)|ensembl:ENST00000442581.1(transcript)|ensembl:ENST00000447092.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001822""(kidney development)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004415""(hyalurononglucosaminidase activity)|go:""GO:0005540""(hyaluronic acid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006027""(glycosaminoglycan catabolic process)|go:""GO:0009615""(response to virus)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019064""(fusion of virus membrane with host plasma membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030294""(receptor signaling protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0033906""(hyaluronoglucuronidase activity)|go:""GO:0035810""(positive regulation of urine volume)|go:""GO:0042117""(monocyte activation)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045121""(membrane raft)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046677""(response to antibiotic)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048705""(skeletal system morphogenesis)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051216""(cartilage development)|go:""GO:0051607""(defense response to virus)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0061099""(negative regulation of protein tyrosine kinase activity)|go:""GO:0070295""(renal water absorption)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071493""(cellular response to UV-B)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018155|reactome:R-HSA-2160916|refseq:NP_003764.3|refseq:NP_149348.2|refseq:XP_005265581.1|refseq:XP_005265582.1|efo:""Orphanet:508476""|panther:PTHR11769(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0ODA76hjR1X3Gra4Y11TcVgihH41392	rogid:NzGpBZoflXudvd2QPKOWRc2NOyk9606	intact-crc:B5D5A2FBC52CFE80|rigid:1m/RpjmMgH5rQil0rw8PjGiILGQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13651	uniprotkb:Q81S27	intact:EBI-1031656|ensembl:ENSP00000227752.4|uniprotkb:B0YJ27|uniprotkb:A8K6I0	intact:EBI-2810215|uniprotkb:Q6I0A6|uniprotkb:Q6KU80	psi-mi:i10r1_human(display_long)|uniprotkb:IL10RA(gene name)|psi-mi:IL10RA(display_short)|uniprotkb:IL10R(gene name synonym)|uniprotkb:Interleukin-10 receptor subunit 1(gene name synonym)|uniprotkb:CDw210a(gene name synonym)	psi-mi:ilvc2_bacan(display_long)|uniprotkb:ilvC2(gene name)|psi-mi:ilvC2(display_short)|uniprotkb:ilvC-2(gene name synonym)|uniprotkb:Acetohydroxy-acid isomeroreductase 2(gene name synonym)|uniprotkb:BA_1852(locus name)|uniprotkb:GBAA_1852(locus name)|uniprotkb:BAS1716(locus name)|uniprotkb:Alpha-keto-beta-hydroxylacyl reductoisomerase 2(gene name synonym)|uniprotkb:Ketol-acid reductoisomerase type 1(gene name synonym)|uniprotkb:Ketol-acid reductoisomerase type I(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2831986|imex:IM-13779-3592	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110324.12(gene)|ensembl:ENST00000227752.8(transcript)|go:""GO:0004920""(interleukin-10 receptor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0019221""(cytokine-mediated signaling pathway)|go:""GO:0019969""(interleukin-10 binding)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050807""(regulation of synapse organization)|go:""GO:0060729""(intestinal epithelial structure maintenance)|go:""GO:0070086""(ubiquitin-dependent endocytosis)|go:""GO:0140105""(interleukin-10-mediated signaling pathway)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR050650|mint:Q13651|rcsb pdb:1J7V|rcsb pdb:1LQS|rcsb pdb:1Y6K|rcsb pdb:1Y6M|rcsb pdb:1Y6N|rcsb pdb:5IXI|rcsb pdb:6X93|reactome:R-HSA-6783783|reactome:R-HSA-9725371|refseq:NP_001549.2|efo:""Orphanet:238569""|dip:DIP-3512N|panther:PTHR20859(orthology-group)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013023(Acetohydroxy acid isomeroreductase)|interpro:IPR000506(Acetohydroxy acid isomeroreductase C-terminal)|interpro:IPR013116(Acetohydroxy acid isomeroreductase, catalytic)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004455""(ketol-acid reductoisomerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0050661""(NADP binding)|refseq:WP_000861162.1|interpro:IPR014359(Ketol-acid reductoisomerase, gammaproteobacteria)|interpro:IPR036291|refseq:NP_844269.1|refseq:YP_027981.1|rcsb pdb:8EP7"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sMAPIcNDOtzRHrmx79PMcP9jDRA9606	rogid:GBngyk+IvD+ZNENclr7Vr+WEkFs1392	intact-crc:B275CF868F2D1E22|rigid:OR6kxXILKCcypZmcolWRO80ywKg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43719	uniprotkb:A0A6L8PKS7	intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|ensembl:ENSP00000218364.4|ensembl:ENSP00000442699.1|intact:EBI-28971035	intact:EBI-2809705|uniprotkb:Q6HR58|uniprotkb:Q6KKH5|uniprotkb:E9QWF2|uniprotkb:E9QWF3|uniprotkb:A0A2P0HL14|uniprotkb:Q81XC3	psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short)|uniprotkb:HIV Tat-specific factor 1(gene name synonym)	psi-mi:a0a6l8pks7_bacan(display_long)|uniprotkb:GBAA_5317(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832000|imex:IM-13779-3593	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001156752.1|refseq:NP_055315.2|ensembl:ENSG00000102241.12(gene)|refseq:XP_005262461.1|rcsb pdb:6Y5Q|rcsb pdb:7EVO|ensembl:ENST00000218364.5(transcript)|ensembl:ENST00000535601.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005684""(U2-type spliceosomal complex)|go:""GO:0005686""(U2 snRNP)|go:""GO:0035861""(site of double-strand break)|go:""GO:0140463""(chromatin-protein adaptor activity)|go:""GO:0160004""(poly-ADP-D-ribose modification-dependent protein binding)|go:""GO:1903241""(U2-type prespliceosome assembly)|go:""GO:1990166""(protein localization to site of double-strand break)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:7Q3L|rcsb pdb:8HK1|reactome:R-HSA-72163|dip:DIP-42095N|panther:PTHR15608(orthology-group)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR051310|interpro:IPR025278|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|refseq:WP_000455036.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/04	rogid:PttL+7D+505QAmcHRGNsc40haPY9606	rogid:LEAQuRzrOsJwYgZq7QXDmoKrfqM1392	intact-crc:EED5C67809B9BAB0|rigid:uQTiC7hMPjmJppVNbbl0SszW6z0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04792	uniprotkb:A0A6L7HDR8	intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|uniprotkb:B2R4N8|ensembl:ENSP00000248553.6	intact:EBI-2813601|uniprotkb:Q6KMC4|uniprotkb:Q6HT37|uniprotkb:E9QVK2|uniprotkb:E9QVK3|uniprotkb:Q81LM9|uniprotkb:A0A0F7R6G5	psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym)|uniprotkb:Heat shock protein family B member 1(gene name synonym)	psi-mi:a0a6l7hdr8_bacan(display_long)|uniprotkb:GBAA_4586(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832058|imex:IM-13779-3599	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106211.11(gene)|ensembl:ENST00000248553.7(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001533""(cornified envelope)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008426""(protein kinase C inhibitor activity)|go:""GO:0009408""(response to heat)|go:""GO:0009615""(response to virus)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042026""(protein refolding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1904115""(axon cytoplasm)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|refseq:NP_001531.1|efo:""Orphanet:139525""|efo:""Orphanet:99940""|dip:DIP-412N|panther:PTHR45640(orthology-group)"	"interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR019774|go:""GO:0005506""(iron ion binding)|go:""GO:0009072""(aromatic amino acid metabolic process)|go:""GO:0016714""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen)|refseq:WP_000163221.1|interpro:IPR036329|interpro:IPR036951"	"psi-mi:""MI:0469""(intact)"	crc64:1B4DC44A6F6606D5	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606	rogid:UgqbKGjZURf/eUAUwQIMUjWsS6Q1392	intact-crc:DEA87D2C01AC9C40|rigid:llHJqVX7TrDBBXT4G6D1+uQQbVU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P2D3	uniprotkb:A0A6H3A739	intact:EBI-2832021|uniprotkb:Q9NVL7|uniprotkb:Q7Z3B2|uniprotkb:B5MDU8|ensembl:ENSP00000233099.5	intact:EBI-2818368|uniprotkb:Q6I310|uniprotkb:Q6KWT2|uniprotkb:E9R4Z5|uniprotkb:E9R4Z6|uniprotkb:Q81US9|uniprotkb:A0A0F7RM22	psi-mi:htr5b_human(display_long)|uniprotkb:HEATR5B(gene name)|psi-mi:HEATR5B(display_short)|uniprotkb:KIAA1414(gene name synonym)|uniprotkb:p200(gene name synonym)|uniprotkb:p200a(gene name synonym)	psi-mi:a0a6h3a739_bacan(display_long)|uniprotkb:GBAA_0781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832030|imex:IM-13779-3601	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011531236.1|refseq:NP_061897.1|ensembl:ENSG00000008869.12(gene)|ensembl:ENST00000233099.6(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0006897""(endocytosis)|go:""GO:0008104""(protein localization)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030139""(endocytic vesicle)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040108|interpro:IPR046837|refseq:XP_016859867.1|panther:PTHR21663(orthology-group)"	"interpro:IPR002781(Protein of unknown function DUF81)|refseq:WP_000060724.1|go:""GO:0005886""(plasma membrane)|interpro:IPR051598"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cz8acySieOoAutwfYv7D1tX065o9606	rogid:8WpRLiHMADTzOEgYV/htixAs/R81392	intact-crc:5652E2BA14579C99|rigid:p4WN+WmbhSApGHjzhDA28J49pMg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UJY1	uniprotkb:A0A6L7HIZ8	intact:EBI-739074|uniprotkb:Q6FIH3|uniprotkb:Q9UKS3|uniprotkb:B2R6A6|ensembl:ENSP00000281938.3	intact:EBI-2815899|uniprotkb:Q6HZP4|uniprotkb:Q6KTN1|uniprotkb:E9R536|uniprotkb:E9R537|uniprotkb:Q81RG9|uniprotkb:A0A0F7RD03	psi-mi:hspb8_human(display_long)|uniprotkb:HSP22(gene name synonym)|uniprotkb:HSPB8(gene name)|psi-mi:HSPB8(display_short)|uniprotkb:CRYAC(gene name synonym)|uniprotkb:E2IG1(gene name synonym)|uniprotkb:PP1629(orf name)|uniprotkb:Alpha-crystallin C chain(gene name synonym)|uniprotkb:Small stress protein-like protein HSP22(gene name synonym)|uniprotkb:E2-induced gene 1 protein(gene name synonym)|uniprotkb:Protein kinase H11(gene name synonym)|uniprotkb:Heat shock protein family B member 8(gene name synonym)	psi-mi:a0a6l7hiz8_bacan(display_long)|uniprotkb:GBAA_2078(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832037|imex:IM-13779-3597	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000152137.8(gene)|ensembl:ENST00000281938.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1905337""(positive regulation of aggrephagy)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR042790|interpro:IPR043254|mint:Q9UJY1|reactome:R-HSA-3371571|refseq:NP_055180.1|efo:""Orphanet:139525""|efo:""Orphanet:476093""|efo:""Orphanet:99945""|panther:PTHR46906(orthology-group)"	refseq:WP_000498015.1|interpro:IPR034660	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SXMGg+TeGqU6CI+A4ypCqCGNYks9606	rogid:AqzZ5oTt9r3TSc7/+boX1fJqMb81392	intact-crc:D4126C7EC5B1E1D3|rigid:QyWtRYzTOOXxxvK1kx2DqvPsT4o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PPL7	uniprotkb:P04792	intact:EBI-2820855|uniprotkb:Q6KKI9|uniprotkb:Q6HR71|uniprotkb:E9QYW1|uniprotkb:E9QYW2|uniprotkb:A0A2P0HL78|uniprotkb:Q81XD7	intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|uniprotkb:B2R4N8|ensembl:ENSP00000248553.6	psi-mi:a0a6l8ppl7_bacan(display_long)|uniprotkb:GBAA_5302(locus name)	psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym)|uniprotkb:Heat shock protein family B member 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832051|imex:IM-13779-3598	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016040(""NAD(P)-binding"")|go:""GO:0016646""(oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor)|refseq:WP_000689817.1|interpro:IPR036291|interpro:IPR051606"	"ensembl:ENSG00000106211.11(gene)|ensembl:ENST00000248553.7(transcript)|go:""GO:0000502""(proteasome complex)|go:""GO:0001533""(cornified envelope)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005925""(focal adhesion)|go:""GO:0006446""(regulation of translational initiation)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0008426""(protein kinase C inhibitor activity)|go:""GO:0009408""(response to heat)|go:""GO:0009615""(response to virus)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030018""(Z disc)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035924""(cellular response to vascular endothelial growth factor stimulus)|go:""GO:0042026""(protein refolding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0099641""(anterograde axonal protein transport)|go:""GO:1902176""(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:""GO:1904115""(axon cytoplasm)|go:""GO:2001028""(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|refseq:NP_001531.1|efo:""Orphanet:139525""|efo:""Orphanet:99940""|dip:DIP-412N|panther:PTHR45640(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	crc64:1B4DC44A6F6606D5	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:1k4lxbZKPNfPGD/o4O59XbFC4EM1392	rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606	intact-crc:D3A326B328F50088|rigid:ANmpQQxq70YDzA/gRYINaO2KxTk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:O14558	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-739095|uniprotkb:O14551|uniprotkb:Q6NVI3|uniprotkb:Q96MG9|ensembl:ENSP00000004982.3	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:hspb6_human(display_long)|uniprotkb:HSPB6(gene name)|psi-mi:HSPB6(display_short)|uniprotkb:Heat shock 20 kDa-like protein p20(gene name synonym)|uniprotkb:Heat shock protein family B member 6(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832044|imex:IM-13779-3600	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"refseq:NP_653218.1|interpro:IPR001436(Alpha crystallin/Heat shock protein)|ensembl:ENSG00000004776.13(gene)|ensembl:ENST00000004982.6(transcript)|go:""GO:0005212""(structural constituent of eye lens)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0009408""(response to heat)|go:""GO:0016607""(nuclear speck)|go:""GO:0042026""(protein refolding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0061077""(chaperone-mediated protein folding)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|mint:O14558|rcsb pdb:4JUS|rcsb pdb:4JUT|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5LUM|rcsb pdb:5OK9|rcsb pdb:5OKF|panther:PTHR45640(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:j4dxIh+W0/K9ofHyEuKfi2GZHBQ9606	intact-crc:EF69251B4AB2196D|rigid:36NlJCDlijQIYsKhssTgTwcn440	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17066	uniprotkb:A0A6L7H1P7	intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219.4	intact:EBI-2832068|uniprotkb:Q6KPS7|uniprotkb:Q6HVL0|uniprotkb:E9QZ69|uniprotkb:E9QZ70|uniprotkb:Q81YB7|uniprotkb:A0A0F7REC5	psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym)|uniprotkb:Heat shock protein family A member 6(gene name synonym)	psi-mi:a0a6l7h1p7_bacan(display_long)|uniprotkb:gerSC(gene name)|psi-mi:gerSC(display_short)|uniprotkb:GBAA_3635(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832065|imex:IM-13779-3602	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002146.2|ensembl:ENSG00000173110.8(gene)|ensembl:ENST00000309758.6(transcript)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005814""(centriole)|go:""GO:0005829""(cytosol)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0042026""(protein refolding)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695|panther:PTHR19375(orthology-group)"	"interpro:IPR008844(Spore germination GerAC)|refseq:WP_001252200.1|go:""GO:0009847""(spore germination)|go:""GO:0016020""(membrane)|interpro:IPR046953|interpro:IPR038501"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606	rogid:qW8m4Sd8UMCehyQDxaclX6674N01392	intact-crc:907AA4F2D9347332|rigid:qXE8ltc/3Hrr4clBgtLuS48Mjn8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08107	uniprotkb:A0A6L7H421	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	intact:EBI-2810652|uniprotkb:Q6KSG7|uniprotkb:Q6HYF9|uniprotkb:E9R9F4|uniprotkb:E9R9F5|uniprotkb:Q81Q87|uniprotkb:A0A0F7RDV9	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:a0a6l7h421_bacan(display_long)|uniprotkb:GBAA_2546(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832085|imex:IM-13779-3603	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0042026""(protein refolding)|go:""GO:0006986""(response to unfolded protein)|refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005829""(cytosol)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005739""(mitochondrion)|go:""GO:0016607""(nuclear speck)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0030529""|go:""GO:0005524""(ATP binding)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0090084""(negative regulation of inclusion body assembly)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0031982""(vesicle)|go:""GO:0010467""(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:""GO:0005654""(nucleoplasm)|go:""GO:1900034""(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:""GO:0016235""(aggresome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0001618""(virus receptor activity)|rcsb pdb:4J8F|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0016234""(inclusion body)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0044822""|go:""GO:0047485""(obsolete protein N-terminus binding)|interpro:IPR029048|ensembl:ENST00000375650|go:""GO:0005814""(centriole)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0034605""(cellular response to heat)|go:""GO:0042623""|go:""GO:0060548""(obsolete negative regulation of cell death)|go:""GO:0070370""(cellular heat acclimation)|interpro:IPR029047|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005925""(focal adhesion)|go:""GO:0031397""(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0050821""(protein stabilization)"	interpro:IPR013560(Protein of unknown function DUF1722)|interpro:IPR007553(Protein of unknown function DUF523)|interpro:IPR017087(Uncharacterised conserved protein UCP037004)|refseq:WP_001248630.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	rogid:2helogO2D/G85c/K2apFD3gNVOc1392	intact-crc:4CD2F4A39F50087D|rigid:T00QlTTgh1asKqMlMynYQtfSYt4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P192	uniprotkb:P08107	intact:EBI-2832095|uniprotkb:Q6I3C9|uniprotkb:Q6KX44|uniprotkb:E9QSC2|uniprotkb:E9QSC3|uniprotkb:A0A2P0HA25|uniprotkb:Q81V44	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:a0a6l8p192_bacan(display_long)|uniprotkb:GBAA_0657(locus name)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832092|imex:IM-13779-3604	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025966|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_000880729.1|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|interpro:IPR035906|interpro:IPR050366"	"go:""GO:0042026""(protein refolding)|go:""GO:0006986""(response to unfolded protein)|refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005829""(cytosol)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005739""(mitochondrion)|go:""GO:0016607""(nuclear speck)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0030529""|go:""GO:0005524""(ATP binding)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0090084""(negative regulation of inclusion body assembly)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0031982""(vesicle)|go:""GO:0010467""(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:""GO:0005654""(nucleoplasm)|go:""GO:1900034""(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:""GO:0016235""(aggresome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0001618""(virus receptor activity)|rcsb pdb:4J8F|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0016234""(inclusion body)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0044822""|go:""GO:0047485""(obsolete protein N-terminus binding)|interpro:IPR029048|ensembl:ENST00000375650|go:""GO:0005814""(centriole)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0034605""(cellular response to heat)|go:""GO:0042623""|go:""GO:0060548""(obsolete negative regulation of cell death)|go:""GO:0070370""(cellular heat acclimation)|interpro:IPR029047|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005925""(focal adhesion)|go:""GO:0031397""(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0050821""(protein stabilization)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:a0uSpZkJ28dkFKvgNR/nXqjUwTE1392	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:EF39B50B0C28DCA0|rigid:1eeVf4LLPdIPCf3qpzcOF+lZ5/8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7R9R7	uniprotkb:P08107	intact:EBI-2811159	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:a0a0f7r9r7_bacan(display_long)|uniprotkb:BA_5304(locus name)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832078|imex:IM-13779-3605	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q81XD5(uniprot-removed-ac)|interpro:IPR004954(Peptidase M60, viral enhancin protein)|refseq:NP_847481.1	"go:""GO:0042026""(protein refolding)|go:""GO:0006986""(response to unfolded protein)|refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:""GO:0005829""(cytosol)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005739""(mitochondrion)|go:""GO:0016607""(nuclear speck)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0030529""|go:""GO:0005524""(ATP binding)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0090084""(negative regulation of inclusion body assembly)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0031982""(vesicle)|go:""GO:0010467""(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:""GO:0005654""(nucleoplasm)|go:""GO:1900034""(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:""GO:0070062""(extracellular exosome)|go:""GO:0072562""(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:""GO:0016235""(aggresome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045648""(positive regulation of erythrocyte differentiation)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0001618""(virus receptor activity)|rcsb pdb:4J8F|go:""GO:2001240""(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0016234""(inclusion body)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0044822""|go:""GO:0047485""(obsolete protein N-terminus binding)|interpro:IPR029048|ensembl:ENST00000375650|go:""GO:0005814""(centriole)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019899""(enzyme binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0034605""(cellular response to heat)|go:""GO:0042623""|go:""GO:0060548""(obsolete negative regulation of cell death)|go:""GO:0070370""(cellular heat acclimation)|interpro:IPR029047|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0005925""(focal adhesion)|go:""GO:0031397""(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0050821""(protein stabilization)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+2A2K0JZVOaQ/UaFJyV7O41Bvos1392	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:71BD08297C3E1BA4|rigid:ZcmR34p8Nd9jV1Ui4gVqJzDI87E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81JT7	uniprotkb:Q00613	intact:EBI-2811219|uniprotkb:Q6KJR4|uniprotkb:Q6HQD6	intact:EBI-719620|uniprotkb:A8MW26|uniprotkb:Q53XT4|uniprotkb:A8K4L0|ensembl:ENSP00000431512.1|ensembl:ENSP00000493830.1	psi-mi:syr1_bacan(display_long)|uniprotkb:argS1(gene name)|psi-mi:argS1(display_short)|uniprotkb:Arginyl-tRNA synthetase 1(gene name synonym)|uniprotkb:BAS5213(locus name)|uniprotkb:BA_5611(locus name)|uniprotkb:GBAA_5611(locus name)	psi-mi:hsf1_human(display_long)|uniprotkb:Heat shock transcription factor 1(gene name synonym)|uniprotkb:HSF1(gene name)|psi-mi:HSF1(display_short)|uniprotkb:HSTF1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832104|imex:IM-13779-3606	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|go:""GO:0004814""(arginine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006420""(arginyl-tRNA aminoacylation)|refseq:WP_001086469.1|interpro:IPR035684|interpro:IPR036695|refseq:NP_847763.1|refseq:YP_031452.1"	"refseq:NP_005517.1|ensembl:ENSG00000185122.11(gene)|ensembl:ENSG00000284774.2(gene)|ensembl:ENST00000528838.6(transcript)|ensembl:ENST00000646252.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000792""(heterochromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001162""(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006397""(mRNA processing)|go:""GO:0006952""(defense response)|go:""GO:0007584""(response to nutrient)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0014823""(response to activity)|go:""GO:0016605""(PML body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0033574""(response to testosterone)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0035865""(cellular response to potassium ion)|go:""GO:0042802""(identical protein binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051028""(mRNA transport)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061770""(translation elongation factor binding)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071276""(cellular response to cadmium ion)|go:""GO:0071280""(cellular response to copper ion)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0072738""(cellular response to diamide)|go:""GO:0090084""(negative regulation of inclusion body assembly)|go:""GO:0090261""(positive regulation of inclusion body assembly)|go:""GO:0097165""(nuclear stress granule)|go:""GO:0097431""(mitotic spindle pole)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0098847""(sequence-specific single stranded DNA binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901652""(response to peptide)|go:""GO:1902512""(positive regulation of apoptotic DNA fragmentation)|go:""GO:1903936""(cellular response to sodium arsenite)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904843""(cellular response to nitroglycerin)|go:""GO:1904845""(cellular response to L-glutamine)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:1990910""(response to hypobaric hypoxia)|go:""GO:1990911""(response to psychosocial stress)|go:""GO:2001033""(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000232(""Heat shock factor (HSF)-type, DNA-binding"")|interpro:IPR010542(Vertebrate heat shock transcription factor)|interpro:IPR036388|interpro:IPR036390|mint:Q00613|rcsb pdb:2LDU|rcsb pdb:5D5U|rcsb pdb:5D5V|rcsb pdb:5HDG|rcsb pdb:5HDN|rcsb pdb:7DCJ|rcsb pdb:7DCS|rcsb pdb:7DCT|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-9646399|reactome:R-HSA-9841251|refseq:XP_016868866.1|dip:DIP-35670N|panther:PTHR10015(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/05	rogid:urOvROG9PysHxGQNMzj+KR6g2Qk1392	rogid:8Kc0CyLMImN2fpNco/AAIbJk+6k9606	intact-crc:618C1074C425121F|rigid:c2bP0zcDP8LQjCkjTzvd6qQWw88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q00839	uniprotkb:A0A0J1I0X6	intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215.1	intact:EBI-2832148|uniprotkb:Q6KT93|uniprotkb:Q6HZ99|uniprotkb:E9RCV7|uniprotkb:E9RCV8|uniprotkb:Q81R29|uniprotkb:A0A1Q4M0G4	psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym)	psi-mi:a0a0j1i0x6_bacan(display_long)|uniprotkb:GBAA_2230(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832145|imex:IM-13779-3611	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:238769""|ensembl:ENSG00000153187.21(gene)|ensembl:ENST00000640218.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000776""(kinetochore)|go:""GO:0000922""(spindle pole)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001097""(TFIIH-class transcription factor complex binding)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0003779""(actin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005697""(telomerase holoenzyme complex)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006396""(RNA processing)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0009048""(dosage compensation by inactivation of X chromosome)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0017069""(snRNA binding)|go:""GO:0017130""(""poly(C) RNA binding"")|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033673""(negative regulation of kinase activity)|go:""GO:0034046""(""poly(G) binding"")|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0034584""(piRNA binding)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0051301""(cell division)|go:""GO:0051457""(maintenance of protein location in nucleus)|go:""GO:0055013""(cardiac muscle cell development)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0070034""(telomerase RNA binding)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0070937""(CRD-mediated mRNA stability complex)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090336""(positive regulation of brown fat cell differentiation)|go:""GO:0098577""(inactive sex chromosome)|go:""GO:0098963""(dendritic transport of messenger ribonucleoprotein complex)|go:""GO:0099122""(RNA polymerase II C-terminal domain binding)|go:""GO:0106222""(lncRNA binding)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901673""(regulation of mitotic spindle assembly)|go:""GO:1902275""(regulation of chromatin organization)|go:""GO:1902425""(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:""GO:1902889""(protein localization to spindle microtubule)|go:""GO:1990023""(mitotic spindle midzone)|go:""GO:1990280""(RNA localization to chromatin)|go:""GO:1990498""(mitotic spindle microtubule)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990845""(adaptive thermogenesis)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|go:""GO:2000648""(positive regulation of stem cell proliferation)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9844594|refseq:NP_004492.2|refseq:NP_114032.2|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N|panther:PTHR12381(orthology-group)"	interpro:IPR025616|refseq:WP_001134414.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606	rogid:ivIsH4Uq5tmHnP9mH7VMv0o1Ihc1392	intact-crc:2506F80520DA9D65|rigid:joo77+YDLl5v32jNYmbgFaWHfNQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q3SXM5	uniprotkb:Q81M96	intact:EBI-1056703|uniprotkb:Q3SXM4|uniprotkb:Q9BY22|uniprotkb:Q8NC98|uniprotkb:D3DUL4|uniprotkb:B4DSL2|ensembl:ENSP00000219439.4	intact:EBI-2832118|uniprotkb:Q6HTP9|uniprotkb:Q6KMY8	psi-mi:hsdl1_human(display_long)|uniprotkb:HSDL1(gene name)|psi-mi:HSDL1(display_short)|uniprotkb:SDR12C3(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 3(gene name synonym)	psi-mi:argj_bacan(display_long)|uniprotkb:argJ(gene name)|psi-mi:argJ(display_short)|uniprotkb:BA_4354(locus name)|uniprotkb:GBAA_4354(locus name)|uniprotkb:BAS4039(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832124|imex:IM-13779-3607	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001139523.1|refseq:NP_113651.4|ensembl:ENSG00000103160.12(gene)|ensembl:ENST00000219439.9(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045111""(intermediate filament cytoskeleton)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|interpro:IPR052149|mint:Q3SXM5|refseq:XP_005256246.1|panther:PTHR44889(orthology-group)"	"refseq:WP_000598413.1|interpro:IPR002813(Arginine biosynthesis protein ArgJ)|interpro:IPR016117(Peptidase S58 DmpA/arginine biosynthesis protein ArgJ)|go:""GO:0004042""(L-glutamate N-acetyltransferase activity)|go:""GO:0004358""(glutamate N-acetyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006592""(ornithine biosynthetic process)|interpro:IPR042195|refseq:NP_846586.1|refseq:YP_030289.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hM3wgoAPVyTT3ma1PhnK5QnOwk89606	rogid:9ZqN4k4xr9PAR+tb7+8ebCYJYd41392	intact-crc:6C1B3296F5A00EA9|rigid:QOHj3RsvwjTV+WcsElEMFJdgKFI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96ED9	uniprotkb:A0A6L7H7Q9	intact:EBI-743290|uniprotkb:O60562|ensembl:ENSP00000380785.2	intact:EBI-2823444|uniprotkb:Q6KJD7|uniprotkb:Q6I2U5|uniprotkb:E9R5Y4|uniprotkb:E9R5Y5|uniprotkb:Q81UL4|uniprotkb:A0A0F7RMR7	psi-mi:hook2_human(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:a0a6l7h7q9_bacan(display_long)|uniprotkb:GBAA_0852(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832131|imex:IM-13779-3609	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001093646.1|refseq:NP_037444.2|ensembl:ENSG00000095066.12(gene)|ensembl:ENST00000397668.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006897""(endocytosis)|go:""GO:0007032""(endosome organization)|go:""GO:0007040""(lysosome organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0015031""(protein transport)|go:""GO:0030705""(cytoskeleton-dependent intracellular transport)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0051959""(dynein light intermediate chain binding)|go:""GO:0070695""(FHF complex)|go:""GO:1905719""(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q96ED9|panther:PTHR18947(orthology-group)"	"interpro:IPR039421|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015421""(ABC-type oligopeptide transporter activity)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000493196.1|interpro:IPR036640"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ryVqr8ZYjAc5SuoRR/zMQxnh0O89606	rogid:I2iOFxwdUv+WSyGorI6ZN5h40hs1392	intact-crc:0948C2CEAC25C3E1|rigid:4gzSL6Vp/MMVeYUPP3sojkk6Mxc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VE1	uniprotkb:Q00613	intact:EBI-2811760|uniprotkb:Q6I4E3|uniprotkb:Q6KY46	intact:EBI-719620|uniprotkb:A8MW26|uniprotkb:Q53XT4|uniprotkb:A8K4L0|ensembl:ENSP00000431512.1|ensembl:ENSP00000493830.1	psi-mi:ch60_bacan(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:BAS0253(locus name)|uniprotkb:BA_0267(locus name)|uniprotkb:GBAA_0267(locus name)	psi-mi:hsf1_human(display_long)|uniprotkb:Heat shock transcription factor 1(gene name synonym)|uniprotkb:HSF1(gene name)|psi-mi:HSF1(display_short)|uniprotkb:HSTF1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832111|imex:IM-13779-3610	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0016853""(isomerase activity)|go:""GO:0042026""(protein refolding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|refseq:WP_001030000.1|interpro:IPR027410|refseq:NP_842820.1|refseq:YP_026537.1"	"refseq:NP_005517.1|ensembl:ENSG00000185122.11(gene)|ensembl:ENSG00000284774.2(gene)|ensembl:ENST00000528838.6(transcript)|ensembl:ENST00000646252.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0000791""(euchromatin)|go:""GO:0000792""(heterochromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001162""(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006397""(mRNA processing)|go:""GO:0006952""(defense response)|go:""GO:0007584""(response to nutrient)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010667""(negative regulation of cardiac muscle cell apoptotic process)|go:""GO:0014823""(response to activity)|go:""GO:0016605""(PML body)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0033574""(response to testosterone)|go:""GO:0034605""(cellular response to heat)|go:""GO:0034620""(cellular response to unfolded protein)|go:""GO:0035865""(cellular response to potassium ion)|go:""GO:0042802""(identical protein binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045931""(positive regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051028""(mRNA transport)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0061770""(translation elongation factor binding)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071276""(cellular response to cadmium ion)|go:""GO:0071280""(cellular response to copper ion)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0072738""(cellular response to diamide)|go:""GO:0090084""(negative regulation of inclusion body assembly)|go:""GO:0090261""(positive regulation of inclusion body assembly)|go:""GO:0097165""(nuclear stress granule)|go:""GO:0097431""(mitotic spindle pole)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0098847""(sequence-specific single stranded DNA binding)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140296""(general transcription initiation factor binding)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901652""(response to peptide)|go:""GO:1902512""(positive regulation of apoptotic DNA fragmentation)|go:""GO:1903936""(cellular response to sodium arsenite)|go:""GO:1904385""(cellular response to angiotensin)|go:""GO:1904843""(cellular response to nitroglycerin)|go:""GO:1904845""(cellular response to L-glutamine)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:1990910""(response to hypobaric hypoxia)|go:""GO:1990911""(response to psychosocial stress)|go:""GO:2001033""(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000232(""Heat shock factor (HSF)-type, DNA-binding"")|interpro:IPR010542(Vertebrate heat shock transcription factor)|interpro:IPR036388|interpro:IPR036390|mint:Q00613|rcsb pdb:2LDU|rcsb pdb:5D5U|rcsb pdb:5D5V|rcsb pdb:5HDG|rcsb pdb:5HDN|rcsb pdb:7DCJ|rcsb pdb:7DCS|rcsb pdb:7DCT|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-9646399|reactome:R-HSA-9841251|refseq:XP_016868866.1|dip:DIP-35670N|panther:PTHR10015(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/05	rogid:rfS7W7PjZAE/lCghNeZHC3DI9IU1392	rogid:8Kc0CyLMImN2fpNco/AAIbJk+6k9606	intact-crc:45A44C74C5EA845B|rigid:UtovCdQCvHxsr/7ThJsLH2qRk2s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q00839	uniprotkb:Q81LD0	intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215.1	intact:EBI-2809803|uniprotkb:Q6KM26|uniprotkb:Q6HST3	psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym)	psi-mi:gsa2_bacan(display_long)|uniprotkb:hemL2(gene name)|psi-mi:hemL2(display_short)|uniprotkb:Glutamate-1-semialdehyde aminotransferase 2(gene name synonym)|uniprotkb:BA_4693(locus name)|uniprotkb:GBAA_4693(locus name)|uniprotkb:BAS4358(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832138|imex:IM-13779-3608	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:238769""|ensembl:ENSG00000153187.21(gene)|ensembl:ENST00000640218.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000228""(nuclear chromosome)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000776""(kinetochore)|go:""GO:0000922""(spindle pole)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0001097""(TFIIH-class transcription factor complex binding)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0003779""(actin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005697""(telomerase holoenzyme complex)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006396""(RNA processing)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0009048""(dosage compensation by inactivation of X chromosome)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016607""(nuclear speck)|go:""GO:0017069""(snRNA binding)|go:""GO:0017130""(""poly(C) RNA binding"")|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033673""(negative regulation of kinase activity)|go:""GO:0034046""(""poly(G) binding"")|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0034584""(piRNA binding)|go:""GO:0036002""(pre-mRNA binding)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:0043021""(ribonucleoprotein complex binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0051301""(cell division)|go:""GO:0051457""(maintenance of protein location in nucleus)|go:""GO:0055013""(cardiac muscle cell development)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0070034""(telomerase RNA binding)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0070937""(CRD-mediated mRNA stability complex)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090336""(positive regulation of brown fat cell differentiation)|go:""GO:0098577""(inactive sex chromosome)|go:""GO:0098963""(dendritic transport of messenger ribonucleoprotein complex)|go:""GO:0099122""(RNA polymerase II C-terminal domain binding)|go:""GO:0106222""(lncRNA binding)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901673""(regulation of mitotic spindle assembly)|go:""GO:1902275""(regulation of chromatin organization)|go:""GO:1902425""(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:""GO:1902889""(protein localization to spindle microtubule)|go:""GO:1990023""(mitotic spindle midzone)|go:""GO:1990280""(RNA localization to chromatin)|go:""GO:1990498""(mitotic spindle microtubule)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990845""(adaptive thermogenesis)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000373""(""positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity"")|go:""GO:2000648""(positive regulation of stem cell proliferation)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9844594|refseq:NP_004492.2|refseq:NP_114032.2|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N|panther:PTHR12381(orthology-group)"	"interpro:IPR004639(Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|rcsb pdb:3K28|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0042286""(glutamate-1-semialdehyde 2,1-aminomutase activity)|refseq:WP_001224513.1|refseq:NP_846906.1|refseq:YP_030605.1|interpro:IPR049704"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606	rogid:GnZPBZpKvZpcwazgpwseq6iVQbg1392	intact-crc:CF72ADFB21CB85FE|rigid:/j8d3wNJ8Z2S5YrBilKDNChzRLw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VV7	uniprotkb:O60506	intact:EBI-2809904|uniprotkb:Q6I4W1|uniprotkb:Q6KYK5	intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635.3|ensembl:ENSP00000503783.1|ensembl:ENSP00000504706.1	psi-mi:disa_bacan(display_long)|uniprotkb:disA(gene name)|psi-mi:disA(display_short)|uniprotkb:Cyclic di-AMP synthase(gene name synonym)|uniprotkb:Diadenylate cyclase(gene name synonym)|uniprotkb:BAS0083(locus name)|uniprotkb:BA_0082(locus name)|uniprotkb:GBAA_0082(locus name)	psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832157|imex:IM-13779-3612	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018906|interpro:IPR003390(Protein of unknown function DUF147)|interpro:IPR023763|interpro:IPR010994(RuvA domain 2-like)|refseq:WP_000392168.1|interpro:IPR050338|go:""GO:0003677""(DNA binding)|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0106408""(diadenylate cyclase activity)|interpro:IPR038331|interpro:IPR036888|refseq:NP_842651.1|refseq:YP_026369.1"	"efo:""Orphanet:528084""|dip:DIP-35540N|ensembl:ENSG00000135316.20(gene)|ensembl:ENST00000369622.8(transcript)|ensembl:ENST00000676688.1(transcript)|ensembl:ENST00000678355.1(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0016556""(mRNA modification)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0045293""(mRNA editing complex)|go:""GO:0048027""(mRNA 5'-UTR binding)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0070937""(CRD-mediated mRNA stability complex)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071204""(histone pre-mRNA 3'end processing complex)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0097452""(GAIT complex)|go:""GO:0106002""(mCRD-mediated mRNA stability complex)|go:""GO:0141166""(chromosomal 5-methylcytosine DNA demethylation pathway)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000623""(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_001240700.1|refseq:NP_006363.4|refseq:XP_005248694.1|refseq:XP_016865667.1|panther:PTHR21245(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:w05jKsotbORB695Nm44K6s+jHHk1392	rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606	intact-crc:74C0252C2C019950|rigid:6GKGXI5GZfsjQTxk+U+mbbwPh8M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P747	uniprotkb:P31942	intact:EBI-2817814|uniprotkb:Q6KTE7|uniprotkb:Q6HZF8|uniprotkb:E9QSG3|uniprotkb:E9QSG4|uniprotkb:Q81JF3|uniprotkb:A0A1Q4M0N4	intact:EBI-711437|ensembl:ENSP00000265866.7|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|uniprotkb:A8K682|uniprotkb:B3KRE1	psi-mi:a0a6l8p747_bacan(display_long)|uniprotkb:GBAA_2171(locus name)	psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832178|imex:IM-13779-3614	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016024(Armadillo-type fold)|interpro:IPR014824(NIF system FeS cluster assembly, NifU-like scaffold, N-terminal)|interpro:IPR004155(PBS lyase HEAT-like repeat)|interpro:IPR025989|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0016829""(lyase activity)|refseq:WP_000692577.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR036498"	"ensembl:ENSG00000096746.18(gene)|ensembl:ENST00000265866.12(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006396""(RNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|interpro:IPR050666|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1|panther:PTHR13976(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YsR6ZqoYDi92S0qkRhcZdI5dzxo1392	rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606	intact-crc:990442E5A2ED8B04|rigid:vr3EsHC8D7iHPY2G0wyWSNm/hxI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14866	uniprotkb:A0A6H3AEH9	intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|ensembl:ENSP00000221419.4|ensembl:ENSP00000489021.1|uniprotkb:A6NIT8	intact:EBI-2825969|uniprotkb:Q6KQA7|uniprotkb:Q6HW51|uniprotkb:E9QXA7|uniprotkb:E9QXA8|uniprotkb:Q81MY8|uniprotkb:A0A1S0QZ62	psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name)	psi-mi:a0a6h3aeh9_bacan(display_long)|uniprotkb:GBAA_3431(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832171|imex:IM-13779-3613	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001005335.1|refseq:NP_001524.2|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|ensembl:ENSG00000104824.18(gene)|ensembl:ENSG00000282947.2(gene)|ensembl:ENST00000221419.10(transcript)|ensembl:ENST00000634753.1(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006396""(RNA processing)|go:""GO:0006397""(mRNA processing)|go:""GO:0016020""(membrane)|go:""GO:0035770""(ribonucleoprotein granule)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097157""(pre-mRNA intronic binding)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|interpro:IPR055204|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|rcsb pdb:7EVR|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_011525191.1|dip:DIP-36355N|panther:PTHR15592(orthology-group)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR004849(6-phosphogluconate dehydrogenase related protein)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|go:""GO:0004616""(""phosphogluconate dehydrogenase (decarboxylating) activity"")|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0016054""(organic acid catabolic process)|go:""GO:0019521""(D-gluconate metabolic process)|go:""GO:0050661""(NADP binding)|refseq:WP_001195906.1|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/20	rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606	rogid:9xewZtuST2DIssVvl7EmWL6KWz81392	intact-crc:53130E1B84878483|rigid:zdONYty1zadP8qpIXDXSp/k7ky0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HKT5	uniprotkb:P52272	intact:EBI-2830360|uniprotkb:Q6HZ84|uniprotkb:Q6KT77|uniprotkb:E9R634|uniprotkb:E9R635|uniprotkb:A0A2P0HDM4|uniprotkb:Q81R13	intact:EBI-486809|ensembl:ENSP00000325376.2|uniprotkb:Q9Y492|uniprotkb:Q15584|uniprotkb:Q8WZ44|uniprotkb:Q96H56|uniprotkb:Q9BWL9|intact:EBI-28985795	psi-mi:a0a6l7hkt5_bacan(display_long)|uniprotkb:GBAA_2246(locus name)	psi-mi:hnrpm_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)|uniprotkb:HNRPM(gene name synonym)|uniprotkb:NAGR1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832164|imex:IM-13779-3615	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003797(DegV)|refseq:WP_003169578.1|go:""GO:0008289""(lipid binding)|interpro:IPR043168|interpro:IPR050270"	"ensembl:ENSG00000099783.13(gene)|ensembl:ENST00000325495.9(transcript)|go:""GO:0000380""(alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005730""(nucleolus)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0042382""(paraspeckles)|go:""GO:0045202""(synapse)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR034990|interpro:IPR035979|interpro:IPR050374|mint:P52272|rcsb pdb:2DGV|rcsb pdb:2DH9|rcsb pdb:2DO0|rcsb pdb:2OT8|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_005959.2|refseq:NP_112480.2|dip:DIP-29336N|panther:PTHR48025(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:H8TGMy9xiNOxV8gWP7WTK7KRoBM1392	rogid:5FnCgrz0xltEkgw3yh70KP2jz5g9606	intact-crc:BEFB12DABA9C4615|rigid:Gb6SrDRG0GjQBnbo0SN/ECj1yfo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31942	uniprotkb:A0A6L8PW84	intact:EBI-711437|ensembl:ENSP00000265866.7|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|uniprotkb:A8K682|uniprotkb:B3KRE1	intact:EBI-2810036|uniprotkb:Q6I0D7|uniprotkb:Q6KUA7|uniprotkb:E9QSG5|uniprotkb:E9QSG6|uniprotkb:Q81S56|uniprotkb:A0A0F7RJG7	psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym)	psi-mi:a0a6l8pw84_bacan(display_long)|uniprotkb:GBAA_1818(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832185|imex:IM-13779-3616	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096746.18(gene)|ensembl:ENST00000265866.12(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006396""(RNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|interpro:IPR050666|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1|panther:PTHR13976(orthology-group)"	"interpro:IPR002901(Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase)|interpro:IPR001119(S-layer homology region)|refseq:WP_000756001.1|interpro:IPR051465|go:""GO:0004040""(amidase activity)|go:""GO:0030115""(S-layer)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606	rogid:rvtlwru3355qXbTQawe6Hx/9UN01392	intact-crc:7C95D483FED7ED89|rigid:fuv6Qag5ghV7N/PAQx/IP1ZuTv0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P77819	uniprotkb:P31943	intact:EBI-2822888|uniprotkb:Q6I4U1|uniprotkb:Q6KYI7|uniprotkb:Q81VT7	intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168.5|ensembl:ENSP00000377082.4|ensembl:ENSP00000397797.2|ensembl:ENSP00000421695.2|ensembl:ENSP00000424087.2|ensembl:ENSP00000425343.2|ensembl:ENSP00000426518.2|ensembl:ENSP00000429661.2|ensembl:ENSP00000492076.2|ensembl:ENSP00000518308.1|ensembl:ENSP00000518309.1|ensembl:ENSP00000518316.1|ensembl:ENSP00000518317.1|ensembl:ENSP00000518318.1|ensembl:ENSP00000518319.1|ensembl:ENSP00000518321.1	psi-mi:rpoc_bacan(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:RNA polymerase subunit beta'(gene name synonym)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:BA_0103(locus name)|uniprotkb:GBAA_0103(locus name)|uniprotkb:BAS0103(locus name)	psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832199|imex:IM-13779-3617	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0008270""(zinc ion binding)|refseq:WP_000567940.1|interpro:IPR038120|interpro:IPR042102|refseq:NP_842671.2|refseq:YP_026389.1|interpro:IPR044893|interpro:IPR045867"	"efo:""Orphanet:662207""|ensembl:ENSG00000169045.19(gene)|ensembl:ENSG00000284254.4(gene)|ensembl:ENST00000356731.9(transcript)|ensembl:ENST00000393432.9(transcript)|ensembl:ENST00000442819.6(transcript)|ensembl:ENST00000505811.6(transcript)|ensembl:ENST00000513225.6(transcript)|ensembl:ENST00000515158.6(transcript)|ensembl:ENST00000515714.6(transcript)|ensembl:ENST00000521116.6(transcript)|ensembl:ENST00000638505.3(transcript)|ensembl:ENST00000710500.1(transcript)|ensembl:ENST00000710502.1(transcript)|ensembl:ENST00000710510.1(transcript)|ensembl:ENST00000710511.1(transcript)|ensembl:ENST00000710512.1(transcript)|ensembl:ENST00000710513.1(transcript)|ensembl:ENST00000710515.1(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008266""(""poly(U) RNA binding"")|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|interpro:IPR050666|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|rcsb pdb:7ZUG|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001244222.1|refseq:NP_005511.1|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1|panther:PTHR13976(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fj+tcN8jEU71jFxqbSrMsyCyJf01392	rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606	intact-crc:6C8605D63AD8CFDC|rigid:BrDxara9ikExHbitYgi35lZxwgk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HH45	uniprotkb:O14979	intact:EBI-2810739|uniprotkb:Q6KQJ9|uniprotkb:Q6HWF0|uniprotkb:E9R0C6|uniprotkb:E9R0C7|uniprotkb:Q81N92|uniprotkb:A0A0F7RF31	intact:EBI-299727|uniprotkb:Q6SPF2|uniprotkb:Q7KZ74|uniprotkb:Q7KZ75|uniprotkb:Q96IM0|uniprotkb:Q96S43|ensembl:ENSP00000295470.5|ensembl:ENSP00000422040.1|ensembl:ENSP00000483254.1	psi-mi:a0a6l7hh45_bacan(display_long)|uniprotkb:GBAA_3323(locus name)	psi-mi:hnrdl_human(display_long)|uniprotkb:HNRNPDL(gene name)|psi-mi:HNRNPDL(display_short)|uniprotkb:AU-rich element RNA-binding factor(gene name synonym)|uniprotkb:HNRPDL(gene name synonym)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:JKTBP(gene name synonym)|uniprotkb:Protein laAUF1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832206|imex:IM-13779-3620	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025672|interpro:IPR029101|go:""GO:0016020""(membrane)|refseq:WP_000180324.1"	"ensembl:ENSG00000152795.18(gene)|ensembl:ENST00000295470.10(transcript)|ensembl:ENST00000502762.4(transcript)|ensembl:ENST00000621267.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0010468""(regulation of gene expression)|go:""GO:0034046""(""poly(G) binding"")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034847|interpro:IPR035979|mint:O14979|rcsb pdb:7ZIR|reactome:R-HSA-8950505|refseq:NP_001193929.1|refseq:NP_112740.1|efo:""Orphanet:55596""|panther:PTHR48033(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WHI2kqITIISGoQqFf8Ewpzg/Ms01392	rogid:oOnEEar8AtKO5G6ldehucaRr4kM9606	intact-crc:436D52ECD1FA21E3|rigid:sOfn2b8tIQxe61KT83Q+y5Slf0M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30519	uniprotkb:A0A6L7HMM5	intact:EBI-712096|uniprotkb:I3L430|uniprotkb:O60605|uniprotkb:A8MT35|uniprotkb:D3DUD5|ensembl:ENSP00000219700.6|ensembl:ENSP00000381595.3|ensembl:ENSP00000385100.2|ensembl:ENSP00000391637.1|ensembl:ENSP00000394103.3|ensembl:ENSP00000459214.1|ensembl:ENSP00000478785.1|ensembl:ENSP00000481295.1|ensembl:ENSP00000481811.1|ensembl:ENSP00000483319.2|ensembl:ENSP00000484422.1|ensembl:ENSP00000484423.1|ensembl:ENSP00000484467.1|ensembl:ENSP00000487673.1|ensembl:ENSP00000488579.1|ensembl:ENSP00000488880.1	intact:EBI-2832220|uniprotkb:Q6I1W1|uniprotkb:Q6KVQ3|uniprotkb:E9R6U8|uniprotkb:E9R6U9|uniprotkb:Q81TN1|uniprotkb:A0A2B6CAB3	psi-mi:hmox2_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)|uniprotkb:HO2(gene name synonym)	psi-mi:a0a6l7hmm5_bacan(display_long)|uniprotkb:GBAA_1240(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832225|imex:IM-13779-3619	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273196.1|refseq:NP_001273197.1|refseq:NP_001273198.1|refseq:NP_001273199.1|refseq:NP_001273200.1|refseq:NP_001120676.1|refseq:NP_001120677.1|refseq:NP_001120678.1|refseq:NP_002125.3|refseq:XP_016878685.1|refseq:XP_016878686.1|dip:DIP-53564N|ensembl:ENSG00000103415.12(gene)|ensembl:ENSG00000277424.4(gene)|ensembl:ENST00000219700.10(transcript)|ensembl:ENST00000398595.7(transcript)|ensembl:ENST00000406590.6(transcript)|ensembl:ENST00000414777.5(transcript)|ensembl:ENST00000458134.7(transcript)|ensembl:ENST00000570646.6(transcript)|ensembl:ENST00000612525.4(transcript)|ensembl:ENST00000615778.4(transcript)|ensembl:ENST00000619528.4(transcript)|ensembl:ENST00000619913.4(transcript)|ensembl:ENST00000620445.3(transcript)|ensembl:ENST00000621065.4(transcript)|ensembl:ENST00000622146.4(transcript)|ensembl:ENST00000631540.1(transcript)|ensembl:ENST00000631677.1(transcript)|ensembl:ENST00000632458.1(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0004392""(""heme oxygenase (decyclizing) activity"")|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006788""(heme oxidation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042167""(heme catabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:P30519|rcsb pdb:2Q32|rcsb pdb:2QPP|rcsb pdb:2RGZ|rcsb pdb:4WMH|rcsb pdb:5UC8|rcsb pdb:5UC9|rcsb pdb:5UCA|reactome:R-HSA-189483|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-917937|reactome:R-HSA-9707564|panther:PTHR10720(orthology-group)"	"interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR039143|refseq:WP_000543277.1|go:""GO:0004343""(glucosamine 6-phosphate N-acetyltransferase activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:yTwXdEjnQgfiFBvl5fhcCwDOJWo9606	rogid:7jFEaRfDUThbDU3wjBJZ3KQO2tE1392	intact-crc:D49AEDA00CD2F9C7|rigid:QccJUTR6Z41rMwqETVwDD2J4OEY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P55795	uniprotkb:A0A6L8Q1C1	intact:EBI-352823|uniprotkb:Q9HHA7|uniprotkb:A1L400|ensembl:ENSP00000361927.2	intact:EBI-2826499|uniprotkb:Q6KMU0|uniprotkb:E9RA66|uniprotkb:Q81M47|uniprotkb:A0A348A9G4	psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym)	psi-mi:a0a6l8q1c1_bacan(display_long)|uniprotkb:Acetyl-coenzyme A carboxylase biotin carboxylase subunit A(gene name synonym)|uniprotkb:accC(gene name)|psi-mi:accC(display_short)|uniprotkb:GBAA_4408(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832192|imex:IM-13779-3621	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000126945.9(gene)|ensembl:ENST00000316594.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|interpro:IPR050666|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|rcsb pdb:8SGH|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001027565.1|refseq:NP_062543.1|efo:""Orphanet:662198""|panther:PTHR13976(orthology-group)"	"interpro:IPR004549(Acetyl-CoA carboxylase, biotin carboxylase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR011054(Rudiment single hybrid motif)|go:""GO:0003989""(acetyl-CoA carboxylase activity)|go:""GO:0004075""(biotin carboxylase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006633""(fatty acid biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:2001295""(malonyl-CoA biosynthetic process)|refseq:WP_000592876.1|interpro:IPR051602"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606	rogid:s2bqK1goRlPZtr6W9nRSvnOchiw1392	intact-crc:7551B5932240132F|rigid:E/yOAdXQUCdvzbJs7ubyRhQ0OBs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14979	uniprotkb:Q81VX8	intact:EBI-299727|uniprotkb:Q6SPF2|uniprotkb:Q7KZ74|uniprotkb:Q7KZ75|uniprotkb:Q96IM0|uniprotkb:Q96S43|ensembl:ENSP00000295470.5|ensembl:ENSP00000422040.1|ensembl:ENSP00000483254.1	intact:EBI-2815444|uniprotkb:Q6KYM6|uniprotkb:E9R6V0	psi-mi:hnrdl_human(display_long)|uniprotkb:HNRNPDL(gene name)|psi-mi:HNRNPDL(display_short)|uniprotkb:AU-rich element RNA-binding factor(gene name synonym)|uniprotkb:HNRPDL(gene name synonym)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:JKTBP(gene name synonym)|uniprotkb:Protein laAUF1(gene name synonym)	psi-mi:q81vx8_bacan(display_long)|uniprotkb:spoIIE(gene name)|psi-mi:spoIIE(display_short)|uniprotkb:GBAA_0061(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832213|imex:IM-13779-3618	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000152795.18(gene)|ensembl:ENST00000295470.10(transcript)|ensembl:ENST00000502762.4(transcript)|ensembl:ENST00000621267.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0010468""(regulation of gene expression)|go:""GO:0034046""(""poly(G) binding"")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034847|interpro:IPR035979|mint:O14979|rcsb pdb:7ZIR|reactome:R-HSA-8950505|refseq:NP_001193929.1|refseq:NP_112740.1|efo:""Orphanet:55596""|panther:PTHR48033(orthology-group)"	"interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR014221(Sporulation stage II, protein E)|go:""GO:0016020""(membrane)|go:""GO:0017018""(myosin phosphatase activity)|go:""GO:0033192""(calmodulin-dependent protein phosphatase activity)|go:""GO:0140791""(histone H2AXS140 phosphatase activity)|go:""GO:0180004""(RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity)|go:""GO:0180005""(RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity)|go:""GO:0180006""(RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity)|go:""GO:0180007""(RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity)|go:""GO:0180008""(RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity)|go:""GO:1990439""(MAP kinase serine/threonine phosphatase activity)|interpro:IPR052016|interpro:IPR036457|interpro:IPR045768"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oOnEEar8AtKO5G6ldehucaRr4kM9606	rogid:QgZVx1OpZ3ZUqC5opdLKf1oRU7s1392	intact-crc:CD466E5C7A576BE8|rigid:lQz7s8XusCE0bcHQTgUWr/y0YuM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09601	uniprotkb:Q81LQ9	intact:EBI-2806151|ensembl:ENSP00000216117.8	intact:EBI-2817908|uniprotkb:Q6KMF4|uniprotkb:E9RE75	psi-mi:hmox1_human(display_long)|uniprotkb:HO(gene name synonym)|uniprotkb:HO1(gene name synonym)|uniprotkb:HMOX1(gene name)|psi-mi:HMOX1(display_short)	psi-mi:q81lq9_bacan(display_long)|uniprotkb:comEA(gene name)|psi-mi:comEA(display_short)|uniprotkb:GBAA_4553(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832253|imex:IM-13779-3624	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100292.18(gene)|ensembl:ENST00000216117.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0002246""(wound healing involved in inflammatory response)|go:""GO:0002686""(negative regulation of leukocyte migration)|go:""GO:0004392""(""heme oxygenase (decyclizing) activity"")|go:""GO:0005198""(structural molecule activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006788""(heme oxidation)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0014806""(smooth muscle hyperplasia)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0019899""(enzyme binding)|go:""GO:0020037""(heme binding)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0034101""(erythrocyte homeostasis)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042167""(heme catabolic process)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048662""(negative regulation of smooth muscle cell proliferation)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0071243""(cellular response to arsenic-containing substance)|go:""GO:0071276""(cellular response to cadmium ion)|go:""GO:0072719""(cellular response to cisplatin)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0110076""(negative regulation of ferroptosis)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903589""(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:P09601|rcsb pdb:1N3U|rcsb pdb:1N45|rcsb pdb:1NI6|rcsb pdb:1OYK|rcsb pdb:1OYL|rcsb pdb:1OZE|rcsb pdb:1OZL|rcsb pdb:1OZR|rcsb pdb:1OZW|rcsb pdb:1S13|rcsb pdb:1S8C|rcsb pdb:1T5P|rcsb pdb:1TWN|rcsb pdb:1TWR|rcsb pdb:1XJZ|rcsb pdb:1XK0|rcsb pdb:1XK1|rcsb pdb:1XK2|rcsb pdb:1XK3|rcsb pdb:3CZY|rcsb pdb:3HOK|rcsb pdb:3K4F|rcsb pdb:3TGM|rcsb pdb:4WD4|rcsb pdb:5BTQ|rcsb pdb:6EHA|reactome:R-HSA-189483|reactome:R-HSA-6785807|reactome:R-HSA-844456|reactome:R-HSA-917937|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-9707564|reactome:R-HSA-9707587|reactome:R-HSA-9707616|reactome:R-HSA-9818027|refseq:NP_002124.1|efo:""Orphanet:562509""|efo:""Orphanet:586""|ensembl:ENSP00000216117.8|panther:PTHR10720(orthology-group)"	"interpro:IPR004509(Competence protein ComEA, helix-hairpin-helix region)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR019554|go:""GO:0003677""(DNA binding)|go:""GO:0006281""(DNA repair)|go:""GO:0015627""(type II protein secretion system complex)|go:""GO:0015628""(protein secretion by the type II secretion system)|go:""GO:0016020""(membrane)|interpro:IPR051675"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Qrwo0mQGREIpHf3DLrvyO6DOLKM9606	rogid:iEvG41gaFu5NjfUyZipFRqUjSKs1392	intact-crc:A5DCECF52CF5CB53|rigid:SujQQPQ2TGMc7NLDf480TUEvcYE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81LD0	uniprotkb:P09601	intact:EBI-2809803|uniprotkb:Q6KM26|uniprotkb:Q6HST3	intact:EBI-2806151|ensembl:ENSP00000216117.8	psi-mi:gsa2_bacan(display_long)|uniprotkb:hemL2(gene name)|psi-mi:hemL2(display_short)|uniprotkb:Glutamate-1-semialdehyde aminotransferase 2(gene name synonym)|uniprotkb:BA_4693(locus name)|uniprotkb:GBAA_4693(locus name)|uniprotkb:BAS4358(locus name)	psi-mi:hmox1_human(display_long)|uniprotkb:HO(gene name synonym)|uniprotkb:HO1(gene name synonym)|uniprotkb:HMOX1(gene name)|psi-mi:HMOX1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832239|imex:IM-13779-3625	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004639(Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|rcsb pdb:3K28|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0042286""(glutamate-1-semialdehyde 2,1-aminomutase activity)|refseq:WP_001224513.1|refseq:NP_846906.1|refseq:YP_030605.1|interpro:IPR049704"	"ensembl:ENSG00000100292.18(gene)|ensembl:ENST00000216117.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0002246""(wound healing involved in inflammatory response)|go:""GO:0002686""(negative regulation of leukocyte migration)|go:""GO:0004392""(""heme oxygenase (decyclizing) activity"")|go:""GO:0005198""(structural molecule activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006788""(heme oxidation)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0014806""(smooth muscle hyperplasia)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0019899""(enzyme binding)|go:""GO:0020037""(heme binding)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0034101""(erythrocyte homeostasis)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042167""(heme catabolic process)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048662""(negative regulation of smooth muscle cell proliferation)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0071243""(cellular response to arsenic-containing substance)|go:""GO:0071276""(cellular response to cadmium ion)|go:""GO:0072719""(cellular response to cisplatin)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0110076""(negative regulation of ferroptosis)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903589""(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:P09601|rcsb pdb:1N3U|rcsb pdb:1N45|rcsb pdb:1NI6|rcsb pdb:1OYK|rcsb pdb:1OYL|rcsb pdb:1OZE|rcsb pdb:1OZL|rcsb pdb:1OZR|rcsb pdb:1OZW|rcsb pdb:1S13|rcsb pdb:1S8C|rcsb pdb:1T5P|rcsb pdb:1TWN|rcsb pdb:1TWR|rcsb pdb:1XJZ|rcsb pdb:1XK0|rcsb pdb:1XK1|rcsb pdb:1XK2|rcsb pdb:1XK3|rcsb pdb:3CZY|rcsb pdb:3HOK|rcsb pdb:3K4F|rcsb pdb:3TGM|rcsb pdb:4WD4|rcsb pdb:5BTQ|rcsb pdb:6EHA|reactome:R-HSA-189483|reactome:R-HSA-6785807|reactome:R-HSA-844456|reactome:R-HSA-917937|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-9707564|reactome:R-HSA-9707587|reactome:R-HSA-9707616|reactome:R-HSA-9818027|refseq:NP_002124.1|efo:""Orphanet:562509""|efo:""Orphanet:586""|ensembl:ENSP00000216117.8|panther:PTHR10720(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GnZPBZpKvZpcwazgpwseq6iVQbg1392	rogid:Qrwo0mQGREIpHf3DLrvyO6DOLKM9606	intact-crc:3379ECF52E4A2F14|rigid:I0bG1p26gRpnPbYbsjbpqVv3HJo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30519	uniprotkb:A0A6L7HFV2	intact:EBI-712096|uniprotkb:I3L430|uniprotkb:O60605|uniprotkb:A8MT35|uniprotkb:D3DUD5|ensembl:ENSP00000219700.6|ensembl:ENSP00000381595.3|ensembl:ENSP00000385100.2|ensembl:ENSP00000391637.1|ensembl:ENSP00000394103.3|ensembl:ENSP00000459214.1|ensembl:ENSP00000478785.1|ensembl:ENSP00000481295.1|ensembl:ENSP00000481811.1|ensembl:ENSP00000483319.2|ensembl:ENSP00000484422.1|ensembl:ENSP00000484423.1|ensembl:ENSP00000484467.1|ensembl:ENSP00000487673.1|ensembl:ENSP00000488579.1|ensembl:ENSP00000488880.1	intact:EBI-2818324|uniprotkb:Q6KPE6|uniprotkb:Q6HV74|uniprotkb:E9QVT9|uniprotkb:E9QVU0|uniprotkb:Q81XX7|uniprotkb:A0A0F7RA63	psi-mi:hmox2_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)|uniprotkb:HO2(gene name synonym)	psi-mi:a0a6l7hfv2_bacan(display_long)|uniprotkb:GBAA_3787(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832232|imex:IM-13779-3622	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001273196.1|refseq:NP_001273197.1|refseq:NP_001273198.1|refseq:NP_001273199.1|refseq:NP_001273200.1|refseq:NP_001120676.1|refseq:NP_001120677.1|refseq:NP_001120678.1|refseq:NP_002125.3|refseq:XP_016878685.1|refseq:XP_016878686.1|dip:DIP-53564N|ensembl:ENSG00000103415.12(gene)|ensembl:ENSG00000277424.4(gene)|ensembl:ENST00000219700.10(transcript)|ensembl:ENST00000398595.7(transcript)|ensembl:ENST00000406590.6(transcript)|ensembl:ENST00000414777.5(transcript)|ensembl:ENST00000458134.7(transcript)|ensembl:ENST00000570646.6(transcript)|ensembl:ENST00000612525.4(transcript)|ensembl:ENST00000615778.4(transcript)|ensembl:ENST00000619528.4(transcript)|ensembl:ENST00000619913.4(transcript)|ensembl:ENST00000620445.3(transcript)|ensembl:ENST00000621065.4(transcript)|ensembl:ENST00000622146.4(transcript)|ensembl:ENST00000631540.1(transcript)|ensembl:ENST00000631677.1(transcript)|ensembl:ENST00000632458.1(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0004392""(""heme oxygenase (decyclizing) activity"")|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006788""(heme oxidation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016020""(membrane)|go:""GO:0020037""(heme binding)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042167""(heme catabolic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:P30519|rcsb pdb:2Q32|rcsb pdb:2QPP|rcsb pdb:2RGZ|rcsb pdb:4WMH|rcsb pdb:5UC8|rcsb pdb:5UC9|rcsb pdb:5UCA|reactome:R-HSA-189483|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-917937|reactome:R-HSA-9707564|panther:PTHR10720(orthology-group)"	"interpro:IPR027417|interpro:IPR005021(Phage Terminase)|go:""GO:0004519""(endonuclease activity)|refseq:WP_001222618.1|interpro:IPR046461|interpro:IPR046462"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:yTwXdEjnQgfiFBvl5fhcCwDOJWo9606	rogid:iK417DPiQ3Ypjwn5KZjvXuIzx2M1392	intact-crc:D92C75CA7B1D415A|rigid:dR9NBagw0lB0og0le707VWx0OiM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A1J9WCP3	uniprotkb:P09601	intact:EBI-2812130|uniprotkb:Q6KXZ3|uniprotkb:Q6I487|uniprotkb:E9R189|uniprotkb:E9R190|uniprotkb:Q81ZE1|uniprotkb:A0A0J1HRK2	intact:EBI-2806151|ensembl:ENSP00000216117.8	psi-mi:a0a1j9wcp3_bacan(display_long)|uniprotkb:GBAA_0328(locus name)	psi-mi:hmox1_human(display_long)|uniprotkb:HO(gene name synonym)|uniprotkb:HO1(gene name synonym)|uniprotkb:HMOX1(gene name)|psi-mi:HMOX1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832246|imex:IM-13779-3623	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000390(Small multidrug resistance protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_000263260.1|interpro:IPR045324"	"ensembl:ENSG00000100292.18(gene)|ensembl:ENST00000216117.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0002246""(wound healing involved in inflammatory response)|go:""GO:0002686""(negative regulation of leukocyte migration)|go:""GO:0004392""(""heme oxygenase (decyclizing) activity"")|go:""GO:0005198""(structural molecule activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006788""(heme oxidation)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0014806""(smooth muscle hyperplasia)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0019899""(enzyme binding)|go:""GO:0020037""(heme binding)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0034101""(erythrocyte homeostasis)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0034605""(cellular response to heat)|go:""GO:0035094""(response to nicotine)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042167""(heme catabolic process)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045765""(regulation of angiogenesis)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048662""(negative regulation of smooth muscle cell proliferation)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0071243""(cellular response to arsenic-containing substance)|go:""GO:0071276""(cellular response to cadmium ion)|go:""GO:0072719""(cellular response to cisplatin)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0110076""(negative regulation of ferroptosis)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1903589""(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:P09601|rcsb pdb:1N3U|rcsb pdb:1N45|rcsb pdb:1NI6|rcsb pdb:1OYK|rcsb pdb:1OYL|rcsb pdb:1OZE|rcsb pdb:1OZL|rcsb pdb:1OZR|rcsb pdb:1OZW|rcsb pdb:1S13|rcsb pdb:1S8C|rcsb pdb:1T5P|rcsb pdb:1TWN|rcsb pdb:1TWR|rcsb pdb:1XJZ|rcsb pdb:1XK0|rcsb pdb:1XK1|rcsb pdb:1XK2|rcsb pdb:1XK3|rcsb pdb:3CZY|rcsb pdb:3HOK|rcsb pdb:3K4F|rcsb pdb:3TGM|rcsb pdb:4WD4|rcsb pdb:5BTQ|rcsb pdb:6EHA|reactome:R-HSA-189483|reactome:R-HSA-6785807|reactome:R-HSA-844456|reactome:R-HSA-917937|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-9707564|reactome:R-HSA-9707587|reactome:R-HSA-9707616|reactome:R-HSA-9818027|refseq:NP_002124.1|efo:""Orphanet:562509""|efo:""Orphanet:586""|ensembl:ENSP00000216117.8|panther:PTHR10720(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kNnvGEtfbtmZ3WYcCWH4ScQCMOU1392	rogid:Qrwo0mQGREIpHf3DLrvyO6DOLKM9606	intact-crc:08DC4EFF7243B6AC|rigid:tF6ccQfkgZXMkrWEyIIFACfGEog	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15651	uniprotkb:Q81YX4	intact:EBI-1758705|uniprotkb:Q7RTT0|uniprotkb:Q969M5|uniprotkb:Q9BZT7|uniprotkb:Q5HYD3|uniprotkb:B2RD37|ensembl:ENSP00000341267.5	intact:EBI-2832260|uniprotkb:Q6KJE3|uniprotkb:E9RBB6	psi-mi:hmgn3_human(display_long)|uniprotkb:HMGN3(gene name)|psi-mi:HMGN3(display_short)|uniprotkb:TRIP7(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 7(gene name synonym)|uniprotkb:PNAS-24(orf name)	psi-mi:q81yx4_bacan(display_long)|uniprotkb:GBAA_0505(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832264|imex:IM-13779-3626	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001305813.1|refseq:NP_001305814.1|refseq:NP_001305815.1|refseq:NP_001305816.1|refseq:NP_001305817.1|refseq:NP_001188291.1|refseq:NP_001188292.1|refseq:NP_004233.1|refseq:NP_620058.1|ensembl:ENSG00000118418.16(gene)|ensembl:ENST00000344726.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|panther:PTHR23087(orthology-group)"	"interpro:IPR029044|interpro:IPR001173(Glycosyl transferase, family 2)|go:""GO:0004582""(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:""GO:0009247""(glycolipid biosynthetic process)|go:""GO:0016020""(membrane)|interpro:IPR039528"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NezCk0zWZWINpJjwvb3i3SWOuCs9606	rogid:R63xY8NIdWoCMo9RF6VIg9ecnMA1392	intact-crc:47F72EB59E80D7FB|rigid:mXS5vYcU9yYPGxkhOWm11LFv2pY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PK65	uniprotkb:Q96RW7	intact:EBI-2814859|uniprotkb:Q6KNB8|uniprotkb:Q6HU34|uniprotkb:E9R566|uniprotkb:E9R567|uniprotkb:Q81MN8|uniprotkb:A0A1J9WN09	intact:EBI-2806183|uniprotkb:Q96DN8|uniprotkb:Q5TYR7|uniprotkb:Q96DN3|uniprotkb:Q96SC3|uniprotkb:A6NGE3|ensembl:ENSP00000271588.4	psi-mi:a0a6l8pk65_bacan(display_long)|uniprotkb:GBAA_4209(locus name)	psi-mi:hmcn1_human(display_long)|uniprotkb:FIBL6(gene name synonym)|uniprotkb:Fibulin-6(gene name synonym)|uniprotkb:HMCN1(gene name)|psi-mi:HMCN1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832278|imex:IM-13779-3627	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR022371|interpro:IPR003695(Ppx/GppA phosphatase)|interpro:IPR050273|go:""GO:0004309""(exopolyphosphatase activity)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006793""(phosphorus metabolic process)|refseq:WP_000658863.1|interpro:IPR043129|interpro:IPR048950"	"refseq:NP_114141.2|refseq:XP_011508340.1|ensembl:ENSG00000143341.12(gene)|ensembl:ENST00000271588.9(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005604""(basement membrane)|go:""GO:0005737""(cytoplasm)|go:""GO:0005912""(adherens junction)|go:""GO:0005927""(muscle tendon junction)|go:""GO:0005938""(cell cortex)|go:""GO:0007156""(homophilic cell adhesion via plasma membrane adhesion molecules)|go:""GO:0007157""(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:""GO:0007601""(visual perception)|go:""GO:0009617""(response to bacterium)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0032154""(cleavage furrow)|go:""GO:0051301""(cell division)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071711""(basement membrane organization)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018097|interpro:IPR026823|interpro:IPR036179|interpro:IPR036383|interpro:IPR036465|interpro:IPR049883|interpro:IPR050958|panther:PTHR23277(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Tp0c5xE9UWFIMW5AXc7XzVCyCSw1392	rogid:hybxCgCN8p6aJ6LoTgeKIfTQzYA9606	intact-crc:0FCBBF5F83A0FD7B|rigid:+wWiZDKcoA+eYwX09aBEOh7g06E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16534	uniprotkb:A0A6L8PTH7	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	intact:EBI-2832302|uniprotkb:Q6KYQ2|uniprotkb:Q6I508|uniprotkb:E9RA42|uniprotkb:E9RA43|uniprotkb:Q81W05|uniprotkb:A0A1S0QQW6	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	"psi-mi:a0a6l8pth7_bacan(display_long)|uniprotkb:rsmI(gene name)|psi-mi:rsmI(display_short)|uniprotkb:16S rRNA 2'-O-ribose C1402 methyltransferase(gene name synonym)|uniprotkb:""rRNA (cytidine-2'-O-)-methyltransferase RsmI""(gene name synonym)|uniprotkb:GBAA_0033(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832299|imex:IM-13779-3629	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"interpro:IPR000878(Tetrapyrrole methylase)|interpro:IPR014777(Tetrapyrrole methylase, subdomain 1)|interpro:IPR008189(Protein of unknown function UPF0011)|interpro:IPR018063|interpro:IPR014776(Tetrapyrrole methylase, subdomain 2)|refseq:WP_000267808.1|go:""GO:0005737""(cytoplasm)|go:""GO:0070677""(""rRNA (cytosine-2'-O-)-methyltransferase activity"")|interpro:IPR035996"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	rogid:uVQPtc5y8BJ9gTlYCRUZ6Bl1m+Q1392	intact-crc:46AE6A4072A9868F|rigid:lKpZkwSc2gyYr7SKg52kN1SFzbk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P05204	uniprotkb:A0A0F7RJB0	intact:EBI-1758689|uniprotkb:Q0VGD5|uniprotkb:Q6FGI5|uniprotkb:Q96C64|ensembl:ENSP00000355228.5	intact:EBI-2827435|uniprotkb:Q6KXD7|uniprotkb:Q6I3M5|uniprotkb:E9R4B4|uniprotkb:E9R4B5|uniprotkb:Q81YS3	psi-mi:hmgn2_human(display_long)|uniprotkb:HMGN2(gene name)|psi-mi:HMGN2(display_short)|uniprotkb:HMG17(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2(gene name synonym)	psi-mi:a0a0f7rjb0_bacan(display_long)|uniprotkb:GBAA_0559(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832271|imex:IM-13779-3631	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005508.1|ensembl:ENSG00000198830.13(gene)|ensembl:ENST00000361427.6(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0003682""(chromatin binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05204|panther:PTHR23087(orthology-group)"	"interpro:IPR033463|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR016120(Signal transduction histidine kinase, sporulation regulator SpoOB)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR029151|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR035965|interpro:IPR036890"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:j8Khsp7BUJh0L9SicpVNR8LP6ZU9606	rogid:QcoG1KEllnFAc5AsQKGhgB/IrHU1392	intact-crc:0A61FC49825CA9BD|rigid:Dz9fzGIkNow34dPx2TGjnf0+VcU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81P27	uniprotkb:Q9NP66	intact:EBI-2814639|uniprotkb:Q6KRC1|uniprotkb:Q6HX99	intact:EBI-740641|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78|ensembl:ENSP00000336856.4|ensembl:ENSP00000371133.3	psi-mi:proa_bacan(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:BA_2992(locus name)|uniprotkb:GBAA_2992(locus name)|uniprotkb:BAS2781(locus name)	psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832292|imex:IM-13779-3628	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|go:""GO:0004350""(glutamate-5-semialdehyde dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0050661""(NADP binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:NP_845325.1|refseq:YP_029039.1|refseq:WP_001006638.1"	"refseq:NP_060670.1|ensembl:ENSG00000140382.15(gene)|ensembl:ENST00000336216.9(transcript)|ensembl:ENST00000381714.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006325""(chromatin organization)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045665""(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR051965|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|panther:PTHR46040(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2iR76/3cLX7gyVDMLNG2KEyBoMY1392	rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606	intact-crc:61A7CA2438EBF415|rigid:5yPAcRUjNop+MM39SKrx7MMlOO0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NP66	uniprotkb:A0A6L7H1G2	intact:EBI-740641|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78|ensembl:ENSP00000336856.4|ensembl:ENSP00000371133.3	intact:EBI-2809927	psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym)	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832285|imex:IM-13779-3630	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060670.1|ensembl:ENSG00000140382.15(gene)|ensembl:ENST00000336216.9(transcript)|ensembl:ENST00000381714.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006325""(chromatin organization)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0033234""(negative regulation of protein sumoylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045665""(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR051965|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|panther:PTHR46040(orthology-group)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	intact-crc:F2F312A54B8F9751|rigid:bQJAuFLZHr0piXXdzUAOBk7xEHY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PU14	uniprotkb:Q16534	intact:EBI-2817545|uniprotkb:Q6KXS2|uniprotkb:Q6I411|uniprotkb:E9R0X4|uniprotkb:E9R0X5|uniprotkb:Q81Z69|uniprotkb:A0A0F7RNN8	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	psi-mi:a0a6l8pu14_bacan(display_long)|uniprotkb:GBAA_0403(locus name)	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832332|imex:IM-13779-3636	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR025647|refseq:WP_000492843.1	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dljX03A4clbrBCvL6AMsyZDP5JQ1392	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	intact-crc:91CCED9F11A5E92B|rigid:WQefbZmxiINjH+PKsJoHXBrGR50	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16534	uniprotkb:A0A6L8P1I7	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	intact:EBI-2809746|uniprotkb:Q6KXV0|uniprotkb:Q6I440|uniprotkb:E9RCC7|uniprotkb:E9RCC8|uniprotkb:A0A2P0H989|uniprotkb:Q81Z98	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	psi-mi:a0a6l8p1i7_bacan(display_long)|uniprotkb:GBAA_0374(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832325|imex:IM-13779-3633	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"interpro:IPR017501(Phage infection protein, YhgE,  C-terminal)|interpro:IPR017500(Phage infection protein, YhgE,  N-terminal)|interpro:IPR051328|go:""GO:0016020""(membrane)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR013525(ABC-2 type transporter)|refseq:WP_000810134.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	rogid:Km4jDuu44pVTrI8b6www/dkgkrY1392	intact-crc:4ADF36E3F4FC5509|rigid:NTDkt2azAzLgPqZue/21w/VJUD4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P1I1	uniprotkb:Q16534	intact:EBI-2821677|uniprotkb:Q6I3B8|uniprotkb:Q6KX35|uniprotkb:E9QYA8|uniprotkb:E9QYA9|uniprotkb:Q81V35|uniprotkb:A0A0F7RN56	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	psi-mi:a0a6l8p1i1_bacan(display_long)|uniprotkb:rbsC(gene name)|psi-mi:rbsC(display_short)|uniprotkb:GBAA_0668(locus name)	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832339|imex:IM-13779-3637	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_001074630.1"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OAncUMVaoHTqcUmUUMhlr5H8wBM1392	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	intact-crc:4B7AAB7BF161CCA9|rigid:f70zCbuZGzKjA8uVCyNHoDrkNNA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16534	uniprotkb:A0A3P1U4V4	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	intact:EBI-2813076|uniprotkb:Q6KWQ3|uniprotkb:E9QYK1|uniprotkb:Q81UP8	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	psi-mi:a0a3p1u4v4_bacan(display_long)|uniprotkb:GBAA_0815(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832318|imex:IM-13779-3635	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"interpro:IPR029052|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR051918|go:""GO:0005737""(cytoplasm)|go:""GO:0016787""(hydrolase activity)|refseq:WP_000376187.1|interpro:IPR036116"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	rogid:0N1cEw1oHnj81QI/96QX0J98dnQ1392	intact-crc:233664CADFD2A2BA|rigid:SxWPUmB8kuAhY+jEP/8c71g74Rg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16534	uniprotkb:A0A6L8NUU6	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	intact:EBI-2832346|uniprotkb:Q6KWP1|uniprotkb:Q6I2W5|uniprotkb:E9QS00|uniprotkb:E9QS01|uniprotkb:A0A2P0HAG3|uniprotkb:Q81UN5	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	psi-mi:a0a6l8nuu6_bacan(display_long)|uniprotkb:GBAA_0829(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832351|imex:IM-13779-3634	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|refseq:WP_001146246.1|go:""GO:0005886""(plasma membrane)|interpro:IPR051258"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	rogid:I5Fe2PPdBXp0J4gs3aH04VzIpO41392	intact-crc:A8826897CEAD1E5A|rigid:QwNMSHRuCvkF653PEWtSUhtg3E8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VT8	uniprotkb:Q16534	intact:EBI-2811891|uniprotkb:Q6I4U2	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832311|imex:IM-13779-3632	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	intact-crc:C7B1B51FC1C3ED26|rigid:M6/J5JmwtAMU7OqlVzQX8alReXM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13747	uniprotkb:Q81ME0	intact:EBI-726583|ensembl:ENSP00000365817.4|ensembl:ENSP00000373091.4|ensembl:ENSP00000390707.2|ensembl:ENSP00000397420.2|ensembl:ENSP00000400458.2|ensembl:ENSP00000402694.2|ensembl:ENSP00000409910.2|uniprotkb:Q30169|uniprotkb:Q9BT83|uniprotkb:Q9GIY7|uniprotkb:Q9GIY8|uniprotkb:E2G051|uniprotkb:Q6DU44	intact:EBI-2813646|uniprotkb:Q6KN28|uniprotkb:Q6HTU1	psi-mi:hlae_human(display_long)|uniprotkb:MHC class I antigen E(gene name synonym)|uniprotkb:HLA-E(gene name)|psi-mi:HLA-E(display_short)|uniprotkb:HLA-6.2(gene name synonym)|uniprotkb:HLAE(gene name synonym)	psi-mi:deob_bacan(display_long)|uniprotkb:deoB(gene name)|psi-mi:deoB(display_short)|uniprotkb:Phosphodeoxyribomutase(gene name synonym)|uniprotkb:BA_4309(locus name)|uniprotkb:GBAA_4309(locus name)|uniprotkb:BAS3997(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832392|imex:IM-13779-3642	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204592.9(gene)|ensembl:ENSG00000206493.7(gene)|ensembl:ENSG00000225201.6(gene)|ensembl:ENSG00000229252.6(gene)|ensembl:ENSG00000230254.7(gene)|ensembl:ENSG00000233904.6(gene)|ensembl:ENSG00000236632.5(gene)|ensembl:ENST00000376630.5(transcript)|ensembl:ENST00000383597.6(transcript)|ensembl:ENST00000415289.4(transcript)|ensembl:ENST00000415649.4(transcript)|ensembl:ENST00000425603.4(transcript)|ensembl:ENST00000427936.4(transcript)|ensembl:ENST00000444683.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001815""(positive regulation of antibody-dependent cellular cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002477""(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0002715""(regulation of natural killer cell mediated immunity)|go:""GO:0002717""(positive regulation of natural killer cell mediated immunity)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032398""(MHC class Ib protein complex)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032759""(positive regulation of TRAIL production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032815""(negative regulation of natural killer cell activation)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0032819""(positive regulation of natural killer cell proliferation)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046703""(natural killer cell lectin-like receptor binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P13747|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1MHE|rcsb pdb:2ESV|rcsb pdb:3AM8|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GL1|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7BH8|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:8QFY|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005507.3|dip:DIP-32N|panther:PTHR16675(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR010045(Phosphopentomutase)|interpro:IPR006124(Metalloenzyme)|interpro:IPR024052|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006015""(5-phosphoribose 1-diphosphate biosynthetic process)|go:""GO:0006018""(2-deoxyribose 1-phosphate catabolic process)|go:""GO:0008973""(phosphopentomutase activity)|go:""GO:0009117""(nucleotide metabolic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0043094""(metabolic compound salvage)|refseq:WP_001046068.1|refseq:NP_846542.1|refseq:YP_030247.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JhlO0lcqZm7whCQasHSnQdrA5Tk9606	rogid:4rSH7u8wKFseFpqFRuqEYAYDNTo1392	intact-crc:C33C821FF5D4E972|rigid:CeoT8fTmYjC82YwCxGG7YWTl9yw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13747	uniprotkb:A0A6L8PWR6	intact:EBI-726583|ensembl:ENSP00000365817.4|ensembl:ENSP00000373091.4|ensembl:ENSP00000390707.2|ensembl:ENSP00000397420.2|ensembl:ENSP00000400458.2|ensembl:ENSP00000402694.2|ensembl:ENSP00000409910.2|uniprotkb:Q30169|uniprotkb:Q9BT83|uniprotkb:Q9GIY7|uniprotkb:Q9GIY8|uniprotkb:E2G051|uniprotkb:Q6DU44	intact:EBI-2832379|uniprotkb:Q6HTX8|uniprotkb:Q6KN60|uniprotkb:E9QQW1|uniprotkb:E9QQW2|uniprotkb:A0A2P0HIF6|uniprotkb:Q81MH9	psi-mi:hlae_human(display_long)|uniprotkb:MHC class I antigen E(gene name synonym)|uniprotkb:HLA-E(gene name)|psi-mi:HLA-E(display_short)|uniprotkb:HLA-6.2(gene name synonym)|uniprotkb:HLAE(gene name synonym)	psi-mi:a0a6l8pwr6_bacan(display_long)|uniprotkb:ptsG(gene name)|psi-mi:ptsG(display_short)|uniprotkb:GBAA_4269(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832385|imex:IM-13779-3640	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204592.9(gene)|ensembl:ENSG00000206493.7(gene)|ensembl:ENSG00000225201.6(gene)|ensembl:ENSG00000229252.6(gene)|ensembl:ENSG00000230254.7(gene)|ensembl:ENSG00000233904.6(gene)|ensembl:ENSG00000236632.5(gene)|ensembl:ENST00000376630.5(transcript)|ensembl:ENST00000383597.6(transcript)|ensembl:ENST00000415289.4(transcript)|ensembl:ENST00000415649.4(transcript)|ensembl:ENST00000425603.4(transcript)|ensembl:ENST00000427936.4(transcript)|ensembl:ENST00000444683.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001815""(positive regulation of antibody-dependent cellular cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002477""(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0002715""(regulation of natural killer cell mediated immunity)|go:""GO:0002717""(positive regulation of natural killer cell mediated immunity)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032398""(MHC class Ib protein complex)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032759""(positive regulation of TRAIL production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032815""(negative regulation of natural killer cell activation)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0032819""(positive regulation of natural killer cell proliferation)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046703""(natural killer cell lectin-like receptor binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P13747|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1MHE|rcsb pdb:2ESV|rcsb pdb:3AM8|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GL1|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7BH8|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:8QFY|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005507.3|dip:DIP-32N|panther:PTHR16675(orthology-group)"	"interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR018113|interpro:IPR004719(Phosphotransferase system, maltose and glucose-specific IIC component)|interpro:IPR001127(Phosphotransferase system, sugar-specific permease EIIA 1 domain)|interpro:IPR001996(Phosphotransferase system, EIIB)|interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR013013(Phosphotransferase system, EIIC component, type 1)|interpro:IPR011299(Phosphotransferase system, glucose-specific IIBC component)|refseq:WP_000473197.1|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0055056""(D-glucose transmembrane transporter activity)|go:""GO:0090563""(protein-phosphocysteine-sugar phosphotransferase activity)|go:""GO:1904659""(D-glucose transmembrane transport)|interpro:IPR036878|interpro:IPR050429"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JhlO0lcqZm7whCQasHSnQdrA5Tk9606	rogid:13VL80aOEjO2UyxWyVYXsoLVlKU1392	intact-crc:04ED5FB5113E6588|rigid:ME36iYMYA+W5C6shfnt38GHMyDk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PZH5	uniprotkb:P30511	intact:EBI-2826162|uniprotkb:Q6KR19|uniprotkb:Q6HWY7|uniprotkb:E9RAS6|uniprotkb:E9RAS7|uniprotkb:Q81NR7|uniprotkb:A0A0F7RFP2	intact:EBI-2811134|uniprotkb:Q5SPT5|uniprotkb:Q9TP68|uniprotkb:Q8WLP5|uniprotkb:Q860R0|uniprotkb:Q5JQJ1|uniprotkb:Q8MGQ1|uniprotkb:Q95HC0|uniprotkb:Q5JQI8|ensembl:ENSP00000334263.4|ensembl:ENSP00000366057.1	psi-mi:a0a6l8pzh5_bacan(display_long)|uniprotkb:GBAA_3110(locus name)	psi-mi:hlaf_human(display_long)|uniprotkb:HLA-F(gene name)|psi-mi:HLA-F(display_short)|uniprotkb:HLA-5.4(gene name synonym)|uniprotkb:HLAF(gene name synonym)|uniprotkb:CDA12(gene name synonym)|uniprotkb:HLA F antigen(gene name synonym)|uniprotkb:Leukocyte antigen F(gene name synonym)|uniprotkb:MHC class I antigen F(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832372|imex:IM-13779-3639	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011642(Nucleoside recognition)|go:""GO:0016020""(membrane)|refseq:WP_001289397.1"	"refseq:NP_001091948.1|refseq:NP_001091949.1|refseq:NP_061823.2|ensembl:ENSG00000204642.14(gene)|ensembl:ENST00000334668.8(transcript)|ensembl:ENST00000376861.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002477""(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002725""(negative regulation of T cell cytokine production)|go:""GO:0002728""(negative regulation of natural killer cell cytokine production)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032398""(MHC class Ib protein complex)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0043322""(negative regulation of natural killer cell degranulation)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046978""(TAP1 binding)|go:""GO:0046979""(TAP2 binding)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P30511|rcsb pdb:5IUE|rcsb pdb:5KNM|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|panther:PTHR16675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:unrZNigCNEdUAEnBz7g1HDmmgmY1392	rogid:rbmQdah7wpa+IyDjP5vDlIA+heM9606	intact-crc:7A1DB3D764041192|rigid:S/EJvuMs4ctzhj0yRvIbPiSl36g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1W4U6	uniprotkb:Q16534	intact:EBI-2814531|uniprotkb:Q6KTH8|uniprotkb:Q6HZI8|uniprotkb:E9QZ61|uniprotkb:E9QZ62|uniprotkb:Q81RB5|uniprotkb:A0A0F7RF35	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	psi-mi:a0a4y1w4u6_bacan(display_long)|uniprotkb:GBAA_2135(locus name)|uniprotkb:moeA1(gene name)|psi-mi:moeA1(display_short)	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832365|imex:IM-13779-3641	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005111(MoeA, C-terminal, domain IV)|interpro:IPR005110(MoeA, N-terminal, domain I and II)|interpro:IPR001453(Molybdopterin binding)|interpro:IPR038987|go:""GO:0005829""(cytosol)|go:""GO:0006777""(Mo-molybdopterin cofactor biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0061599""(molybdopterin molybdotransferase activity)|interpro:IPR036135|interpro:IPR036425|interpro:IPR036688|refseq:WP_000880220.1"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:r8E0EfyfJU7lnseaLwPX1Eah4wo1392	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	intact-crc:A5C0265E4BA95169|rigid:upK0Wwqx2liaiiMBIJu1cGwVxMg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HHX2	uniprotkb:Q16534	intact:EBI-2812285|uniprotkb:Q6KUB0|uniprotkb:Q6I0E0|uniprotkb:E9QSI8|uniprotkb:E9QSI9|uniprotkb:Q81S59|uniprotkb:A0A0F7RKM4	intact:EBI-2798854|ensembl:ENSP00000226067.5|uniprotkb:A8K1X8|uniprotkb:Q6FHS9	psi-mi:a0a6l7hhx2_bacan(display_long)|uniprotkb:GBAA_1815(locus name)	psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832358|imex:IM-13779-3638	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025450|go:""GO:0016020""(membrane)|refseq:WP_000789548.1"	"ensembl:ENSG00000108924.14(gene)|ensembl:ENST00000226067.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048511""(rhythmic process)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR040223|interpro:IPR046347|refseq:NP_001317304.1|refseq:NP_002117.1|efo:""Orphanet:641375""|panther:PTHR11988(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:g0iSNc7Mh4tgNaBj+nHYsEjH5sY1392	rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606	intact-crc:DA6042B53F7EF2CE|rigid:wvwJGt3OeNrI1i0zop/7QW+zasE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13747	uniprotkb:Q81R83	intact:EBI-726583|ensembl:ENSP00000365817.4|ensembl:ENSP00000373091.4|ensembl:ENSP00000390707.2|ensembl:ENSP00000397420.2|ensembl:ENSP00000400458.2|ensembl:ENSP00000402694.2|ensembl:ENSP00000409910.2|uniprotkb:Q30169|uniprotkb:Q9BT83|uniprotkb:Q9GIY7|uniprotkb:Q9GIY8|uniprotkb:E2G051|uniprotkb:Q6DU44	intact:EBI-2810574|uniprotkb:Q6KTE5|uniprotkb:Q6HZF6	psi-mi:hlae_human(display_long)|uniprotkb:MHC class I antigen E(gene name synonym)|uniprotkb:HLA-E(gene name)|psi-mi:HLA-E(display_short)|uniprotkb:HLA-6.2(gene name synonym)|uniprotkb:HLAE(gene name synonym)	psi-mi:y2173_bacan(display_long)|uniprotkb:BA_2173(locus name)|uniprotkb:GBAA_2173(locus name)|uniprotkb:BAS2019(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832406|imex:IM-13779-3643	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204592.9(gene)|ensembl:ENSG00000206493.7(gene)|ensembl:ENSG00000225201.6(gene)|ensembl:ENSG00000229252.6(gene)|ensembl:ENSG00000230254.7(gene)|ensembl:ENSG00000233904.6(gene)|ensembl:ENSG00000236632.5(gene)|ensembl:ENST00000376630.5(transcript)|ensembl:ENST00000383597.6(transcript)|ensembl:ENST00000415289.4(transcript)|ensembl:ENST00000415649.4(transcript)|ensembl:ENST00000425603.4(transcript)|ensembl:ENST00000427936.4(transcript)|ensembl:ENST00000444683.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001815""(positive regulation of antibody-dependent cellular cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002477""(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0002715""(regulation of natural killer cell mediated immunity)|go:""GO:0002717""(positive regulation of natural killer cell mediated immunity)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032398""(MHC class Ib protein complex)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032759""(positive regulation of TRAIL production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032815""(negative regulation of natural killer cell activation)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0032819""(positive regulation of natural killer cell proliferation)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046703""(natural killer cell lectin-like receptor binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P13747|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1MHE|rcsb pdb:2ESV|rcsb pdb:3AM8|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GL1|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7BH8|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:8QFY|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005507.3|dip:DIP-32N|panther:PTHR16675(orthology-group)"	"interpro:IPR009474(Protein of unknown function DUF1094)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_000063712.1|refseq:NP_844566.1|refseq:YP_028282.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JhlO0lcqZm7whCQasHSnQdrA5Tk9606	rogid:DwG1RQbAdj088ZOY9O74UrEBXms1392	intact-crc:517F4D1FF520D697|rigid:1e1jaZwlIf+Sj6K1lSPNLC0Q+QI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49773	uniprotkb:A0A6L8PRR8	intact:EBI-1054330|uniprotkb:Q9H5W8|ensembl:ENSP00000304229.5	intact:EBI-2811394|uniprotkb:Q6I2G7|uniprotkb:Q6KW94|uniprotkb:E9R8J0|uniprotkb:E9R8J1|uniprotkb:Q81U80|uniprotkb:A0A0F7RLC1	psi-mi:hint1_human(display_long)|uniprotkb:Protein kinase C inhibitor 1(gene name synonym)|uniprotkb:Protein kinase C-interacting protein 1(gene name synonym)|uniprotkb:HINT1(gene name)|psi-mi:HINT1(display_short)|uniprotkb:HINT(gene name synonym)|uniprotkb:PKCI1(gene name synonym)|uniprotkb:PRKCNH1(gene name synonym)|uniprotkb:Desumoylating isopeptidase HINT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein 1(gene name synonym)	psi-mi:a0a6l8prr8_bacan(display_long)|uniprotkb:GBAA_1004(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832432|imex:IM-13779-3645	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:324442""|ensembl:ENSG00000169567.13(gene)|ensembl:ENST00000304043.10(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000166""(nucleotide binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006508""(proteolysis)|go:""GO:0007165""(signal transduction)|go:""GO:0009154""(purine ribonucleotide catabolic process)|go:""GO:0016787""(hydrolase activity)|go:""GO:0016926""(protein desumoylation)|go:""GO:0016929""(deSUMOylase activity)|go:""GO:0043530""(adenosine 5'-monophosphoramidase activity)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310(""Histidine triad (HIT) protein"")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|mint:P49773|rcsb pdb:1AV5|rcsb pdb:1KPA|rcsb pdb:1KPB|rcsb pdb:1KPC|rcsb pdb:1KPE|rcsb pdb:1KPF|rcsb pdb:3TW2|rcsb pdb:4EQE|rcsb pdb:4EQG|rcsb pdb:4EQH|rcsb pdb:4ZKL|rcsb pdb:4ZKV|rcsb pdb:5ED3|rcsb pdb:5ED6|rcsb pdb:5EMT|rcsb pdb:5I2E|rcsb pdb:5I2F|rcsb pdb:5IPB|rcsb pdb:5IPC|rcsb pdb:5IPD|rcsb pdb:5IPE|rcsb pdb:5KLY|rcsb pdb:5KLZ|rcsb pdb:5KM0|rcsb pdb:5KM1|rcsb pdb:5KM2|rcsb pdb:5KM3|rcsb pdb:5KM4|rcsb pdb:5KM6|rcsb pdb:5KMA|rcsb pdb:5KMB|rcsb pdb:5KMC|rcsb pdb:5O8I|rcsb pdb:5WA8|rcsb pdb:5WA9|rcsb pdb:5WAA|rcsb pdb:6B42|rcsb pdb:6G9Z|rcsb pdb:6J53|rcsb pdb:6J58|rcsb pdb:6J5S|rcsb pdb:6J5Z|rcsb pdb:6J64|rcsb pdb:6J65|rcsb pdb:6N3V|rcsb pdb:6N3W|rcsb pdb:6N3X|rcsb pdb:6N3Y|rcsb pdb:6YQM|rcsb pdb:7Q2U|rcsb pdb:8P8P|rcsb pdb:8PA6|rcsb pdb:8PA9|rcsb pdb:8PAF|rcsb pdb:8PAI|rcsb pdb:8PWK|rcsb pdb:8WZD|reactome:R-HSA-9824594|reactome:R-HSA-9825892|reactome:R-HSA-9856649|refseq:NP_005331.1|panther:PTHR23089(orthology-group)"	"interpro:IPR020843|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR011032(GroES-like)|go:""GO:0016651""(""oxidoreductase activity, acting on NAD(P)H"")|go:""GO:0070402""(NADPH binding)|refseq:WP_000902291.1|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vXotU/cqS8hSHeBmCk30zSQ9k/E9606	rogid:bJoUAV4WZkl9RHHmLvJxDPIL7Wk1392	intact-crc:E150833C3D6E339D|rigid:7xqds677fzBHhfKw9xl1hDLsoXo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13747	uniprotkb:A0A6L7HRV6	intact:EBI-726583|ensembl:ENSP00000365817.4|ensembl:ENSP00000373091.4|ensembl:ENSP00000390707.2|ensembl:ENSP00000397420.2|ensembl:ENSP00000400458.2|ensembl:ENSP00000402694.2|ensembl:ENSP00000409910.2|uniprotkb:Q30169|uniprotkb:Q9BT83|uniprotkb:Q9GIY7|uniprotkb:Q9GIY8|uniprotkb:E2G051|uniprotkb:Q6DU44	intact:EBI-2832416|uniprotkb:Q6KXT9|uniprotkb:Q6I429|uniprotkb:E9R386|uniprotkb:E9R387|uniprotkb:A0A2P0H9C3|uniprotkb:Q81Z87	psi-mi:hlae_human(display_long)|uniprotkb:MHC class I antigen E(gene name synonym)|uniprotkb:HLA-E(gene name)|psi-mi:HLA-E(display_short)|uniprotkb:HLA-6.2(gene name synonym)|uniprotkb:HLAE(gene name synonym)	psi-mi:a0a6l7hrv6_bacan(display_long)|uniprotkb:GBAA_0385(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832413|imex:IM-13779-3646	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204592.9(gene)|ensembl:ENSG00000206493.7(gene)|ensembl:ENSG00000225201.6(gene)|ensembl:ENSG00000229252.6(gene)|ensembl:ENSG00000230254.7(gene)|ensembl:ENSG00000233904.6(gene)|ensembl:ENSG00000236632.5(gene)|ensembl:ENST00000376630.5(transcript)|ensembl:ENST00000383597.6(transcript)|ensembl:ENST00000415289.4(transcript)|ensembl:ENST00000415649.4(transcript)|ensembl:ENST00000425603.4(transcript)|ensembl:ENST00000427936.4(transcript)|ensembl:ENST00000444683.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001815""(positive regulation of antibody-dependent cellular cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002477""(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0002715""(regulation of natural killer cell mediated immunity)|go:""GO:0002717""(positive regulation of natural killer cell mediated immunity)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032398""(MHC class Ib protein complex)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032759""(positive regulation of TRAIL production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032815""(negative regulation of natural killer cell activation)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0032819""(positive regulation of natural killer cell proliferation)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046703""(natural killer cell lectin-like receptor binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P13747|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1MHE|rcsb pdb:2ESV|rcsb pdb:3AM8|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GL1|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7BH8|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:8QFY|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005507.3|dip:DIP-32N|panther:PTHR16675(orthology-group)"	"interpro:IPR008965(Carbohydrate-binding)|interpro:IPR001919(Cellulose-binding, family II, bacterial type)|interpro:IPR011583(Chitinase II)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029070|refseq:WP_000837181.1|go:""GO:0004568""(chitinase activity)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0030247""(polysaccharide binding)|interpro:IPR012291(Cellulose-binding family II/chitobiase, carbohydrate-binding)|interpro:IPR036116|interpro:IPR050314"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JhlO0lcqZm7whCQasHSnQdrA5Tk9606	rogid:I4hK26GFIM7C8r3ZgujTjMnow6w1392	intact-crc:4A1E34495D8C6C36|rigid:5sp4HubXhtWw+Qe7axuZ4rAl0gg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13747	uniprotkb:A0A2P0HHU3	intact:EBI-726583|ensembl:ENSP00000365817.4|ensembl:ENSP00000373091.4|ensembl:ENSP00000390707.2|ensembl:ENSP00000397420.2|ensembl:ENSP00000400458.2|ensembl:ENSP00000402694.2|ensembl:ENSP00000409910.2|uniprotkb:Q30169|uniprotkb:Q9BT83|uniprotkb:Q9GIY7|uniprotkb:Q9GIY8|uniprotkb:E2G051|uniprotkb:Q6DU44	intact:EBI-2811119|uniprotkb:Q6KPA1|uniprotkb:E9RCY6|uniprotkb:Q81WX2	psi-mi:hlae_human(display_long)|uniprotkb:MHC class I antigen E(gene name synonym)|uniprotkb:HLA-E(gene name)|psi-mi:HLA-E(display_short)|uniprotkb:HLA-6.2(gene name synonym)|uniprotkb:HLAE(gene name synonym)	psi-mi:a0a2p0hhu3_bacan(display_long)|uniprotkb:GBAA_3841(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832399|imex:IM-13779-3647	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204592.9(gene)|ensembl:ENSG00000206493.7(gene)|ensembl:ENSG00000225201.6(gene)|ensembl:ENSG00000229252.6(gene)|ensembl:ENSG00000230254.7(gene)|ensembl:ENSG00000233904.6(gene)|ensembl:ENSG00000236632.5(gene)|ensembl:ENST00000376630.5(transcript)|ensembl:ENST00000383597.6(transcript)|ensembl:ENST00000415289.4(transcript)|ensembl:ENST00000415649.4(transcript)|ensembl:ENST00000425603.4(transcript)|ensembl:ENST00000427936.4(transcript)|ensembl:ENST00000444683.4(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001815""(positive regulation of antibody-dependent cellular cytotoxicity)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002477""(antigen processing and presentation of exogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002519""(natural killer cell tolerance induction)|go:""GO:0002639""(positive regulation of immunoglobulin production)|go:""GO:0002715""(regulation of natural killer cell mediated immunity)|go:""GO:0002717""(positive regulation of natural killer cell mediated immunity)|go:""GO:0002729""(positive regulation of natural killer cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032398""(MHC class Ib protein complex)|go:""GO:0032736""(positive regulation of interleukin-13 production)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032759""(positive regulation of TRAIL production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032815""(negative regulation of natural killer cell activation)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0032819""(positive regulation of natural killer cell proliferation)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042270""(protection from natural killer cell mediated cytotoxicity)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0045087""(innate immune response)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046703""(natural killer cell lectin-like receptor binding)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0055038""(recycling endosome membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P13747|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1MHE|rcsb pdb:2ESV|rcsb pdb:3AM8|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GL1|rcsb pdb:6ZKW|rcsb pdb:6ZKX|rcsb pdb:6ZKY|rcsb pdb:6ZKZ|rcsb pdb:7BH8|rcsb pdb:7NDQ|rcsb pdb:7NDT|rcsb pdb:7NDU|rcsb pdb:7P49|rcsb pdb:7P4B|rcsb pdb:8QFY|rcsb pdb:8RLT|rcsb pdb:8RLU|rcsb pdb:8RLV|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-9705671|reactome:R-HSA-983170|refseq:NP_005507.3|dip:DIP-32N|panther:PTHR16675(orthology-group)"	"interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR050149|go:""GO:0005615""(extracellular space)|go:""GO:0030020""(extracellular matrix structural constituent conferring tensile strength)|go:""GO:0030198""(extracellular matrix organization)|refseq:WP_000092465.1|interpro:IPR048009"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JhlO0lcqZm7whCQasHSnQdrA5Tk9606	rogid:bOpkW2SnpXGvNsOHSbPKRkQYwxw1392	intact-crc:2D62E123D9370DF9|rigid:NOy4vgxXVo7cywM2Sqra/6+SCN0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NVB0	uniprotkb:P49773	intact:EBI-2811493|uniprotkb:Q6KWL2|uniprotkb:Q6I2T1|uniprotkb:E9R8N8|uniprotkb:E9R8N9|uniprotkb:Q81UK2|uniprotkb:A0A0F7RLK2	intact:EBI-1054330|uniprotkb:Q9H5W8|ensembl:ENSP00000304229.5	psi-mi:a0a6l8nvb0_bacan(display_long)|uniprotkb:alsS(gene name)|psi-mi:alsS(display_short)|uniprotkb:GBAA_0866(locus name)	psi-mi:hint1_human(display_long)|uniprotkb:Protein kinase C inhibitor 1(gene name synonym)|uniprotkb:Protein kinase C-interacting protein 1(gene name synonym)|uniprotkb:HINT1(gene name)|psi-mi:HINT1(display_short)|uniprotkb:HINT(gene name synonym)|uniprotkb:PKCI1(gene name synonym)|uniprotkb:PRKCNH1(gene name synonym)|uniprotkb:Desumoylating isopeptidase HINT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832425|imex:IM-13779-3644	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012782(Acetolactate synthase, catabolic)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR029035|interpro:IPR029061|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003984""(acetolactate synthase activity)|go:""GO:0005948""(acetolactate synthase complex)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0034077""(butanediol metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_000103511.1|interpro:IPR045229"	"efo:""Orphanet:324442""|ensembl:ENSG00000169567.13(gene)|ensembl:ENST00000304043.10(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000166""(nucleotide binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006508""(proteolysis)|go:""GO:0007165""(signal transduction)|go:""GO:0009154""(purine ribonucleotide catabolic process)|go:""GO:0016787""(hydrolase activity)|go:""GO:0016926""(protein desumoylation)|go:""GO:0016929""(deSUMOylase activity)|go:""GO:0043530""(adenosine 5'-monophosphoramidase activity)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072332""(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310(""Histidine triad (HIT) protein"")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|mint:P49773|rcsb pdb:1AV5|rcsb pdb:1KPA|rcsb pdb:1KPB|rcsb pdb:1KPC|rcsb pdb:1KPE|rcsb pdb:1KPF|rcsb pdb:3TW2|rcsb pdb:4EQE|rcsb pdb:4EQG|rcsb pdb:4EQH|rcsb pdb:4ZKL|rcsb pdb:4ZKV|rcsb pdb:5ED3|rcsb pdb:5ED6|rcsb pdb:5EMT|rcsb pdb:5I2E|rcsb pdb:5I2F|rcsb pdb:5IPB|rcsb pdb:5IPC|rcsb pdb:5IPD|rcsb pdb:5IPE|rcsb pdb:5KLY|rcsb pdb:5KLZ|rcsb pdb:5KM0|rcsb pdb:5KM1|rcsb pdb:5KM2|rcsb pdb:5KM3|rcsb pdb:5KM4|rcsb pdb:5KM6|rcsb pdb:5KMA|rcsb pdb:5KMB|rcsb pdb:5KMC|rcsb pdb:5O8I|rcsb pdb:5WA8|rcsb pdb:5WA9|rcsb pdb:5WAA|rcsb pdb:6B42|rcsb pdb:6G9Z|rcsb pdb:6J53|rcsb pdb:6J58|rcsb pdb:6J5S|rcsb pdb:6J5Z|rcsb pdb:6J64|rcsb pdb:6J65|rcsb pdb:6N3V|rcsb pdb:6N3W|rcsb pdb:6N3X|rcsb pdb:6N3Y|rcsb pdb:6YQM|rcsb pdb:7Q2U|rcsb pdb:8P8P|rcsb pdb:8PA6|rcsb pdb:8PA9|rcsb pdb:8PAF|rcsb pdb:8PAI|rcsb pdb:8PWK|rcsb pdb:8WZD|reactome:R-HSA-9824594|reactome:R-HSA-9825892|reactome:R-HSA-9856649|refseq:NP_005331.1|panther:PTHR23089(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rRCMmJc9HuwjVl3UsPYv6jvntSI1392	rogid:vXotU/cqS8hSHeBmCk30zSQ9k/E9606	intact-crc:E472ED8655A3B4A3|rigid:FyAhyCx9UqAJQiCYDItdnddQAbw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81TW1	uniprotkb:P04233	intact:EBI-2810929|uniprotkb:Q6I247|uniprotkb:Q6KVY3	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:adda_bacan(display_long)|uniprotkb:addA(gene name)|psi-mi:addA(display_short)|uniprotkb:DNA 3'-5' helicase AddA(gene name synonym)|uniprotkb:BAS1061(locus name)|uniprotkb:BA_1142(locus name)|uniprotkb:GBAA_1142(locus name)|uniprotkb:ATP-dependent helicase/nuclease AddA(gene name synonym)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832460|imex:IM-13779-3650	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014152(""DNA helicase (recombination ), AddA type"")|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR038726|interpro:IPR027417|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0033202""(DNA helicase complex)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|refseq:WP_000970458.1|refseq:NP_843626.1|refseq:YP_027333.1"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mjbRVJQHL4JcpSJqsALgvEqgiMk1392	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:B36C021B1D2818CC|rigid:9iQDXjkVVBllvDbtPzekZqdqZ3o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:P04233	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832467|imex:IM-13779-3652	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:85A3AF3D776749B1|rigid:OEBPApyIyjDRMfYUxpt3x4tBfiE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5I8	uniprotkb:O14964	intact:EBI-2820109|uniprotkb:Q6HY62|uniprotkb:Q6KS76|uniprotkb:E9QSG7|uniprotkb:E9QSG8|uniprotkb:Q81PZ2|uniprotkb:A0A0J1I4S2	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201.4|ensembl:ENSP00000504106.1	psi-mi:a0a6l7h5i8_bacan(display_long)|uniprotkb:GBAA_2647(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832439|imex:IM-13779-3648	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000644533.1|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR011032(GroES-like)|interpro:IPR020843|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR052711|interpro:IPR036291"	"refseq:NP_004703.1|ensembl:ENSG00000185359.14(gene)|ensembl:ENST00000329138.9(transcript)|ensembl:ENST00000676546.1(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0007165""(signal transduction)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010324""(membrane invagination)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010642""(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:""GO:0016197""(endosomal transport)|go:""GO:0016236""(macroautophagy)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0031623""(receptor internalization)|go:""GO:0031901""(early endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032585""(multivesicular body membrane)|go:""GO:0033565""(ESCRT-0 complex)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0042176""(regulation of protein catabolic process)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043405""(regulation of MAP kinase activity)|go:""GO:0044389""(ubiquitin-like protein ligase binding)|go:""GO:0046426""(negative regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0090148""(membrane fission)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:1903543""(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|dip:DIP-29050N|panther:PTHR46275(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:MAC3CsiJ5bB1Sm1kgUwJzzfeKIY1392	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:CC20CD2696F9C6F9|rigid:wFLt1DJFIWqh1sN9f+AF/sr5EUs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04233	uniprotkb:A0A6L8PX73	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-2814460|uniprotkb:Q6HTD2|uniprotkb:Q6KMM4|uniprotkb:E9R6D4|uniprotkb:E9R6D5|uniprotkb:Q81LY0|uniprotkb:A0A0J1HYA4	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:a0a6l8px73_bacan(display_long)|uniprotkb:GBAA_4479(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832453|imex:IM-13779-3649	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"interpro:IPR003171(Methylenetetrahydrofolate reductase)|interpro:IPR003726(Homocysteine S-methyltransferase)|interpro:IPR050554|interpro:IPR029041|go:""GO:0004489""(""methylenetetrahydrofolate reductase (NAD(P)H) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0008705""(methionine synthase activity)|go:""GO:0032259""(methylation)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|refseq:WP_000770331.1|interpro:IPR036589"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:kwYps3uM+vfuLmFjfNZe8XCRW/U1392	intact-crc:BC22E5D62A0E921A|rigid:6IWqhPQJk/FpSyVnEqdVimrvTdk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04233	uniprotkb:A0A6H3AL29	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-2815022|uniprotkb:Q6KP86|uniprotkb:Q6HV12|uniprotkb:E9QUK5|uniprotkb:E9QUK6|uniprotkb:Q81WV8|uniprotkb:A0A0J1I450	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:a0a6h3al29_bacan(display_long)|uniprotkb:GBAA_3857(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832446|imex:IM-13779-3651	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"interpro:IPR000292(Formate/nitrite transporter)|interpro:IPR024002|interpro:IPR023271|go:""GO:0005886""(plasma membrane)|go:""GO:0015499""(formate transmembrane transporter activity)|refseq:WP_000110521.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:9zuhNcbWkPnfpCTp+1paFSJCwEY1392	intact-crc:8EAC20190140A8FD|rigid:toWz+ZcVvsQNtB2ZWg1Z85CiP+g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81LD0	uniprotkb:O94992	intact:EBI-2809803|uniprotkb:Q6KM26|uniprotkb:Q6HST3	intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773.3	psi-mi:gsa2_bacan(display_long)|uniprotkb:hemL2(gene name)|psi-mi:hemL2(display_short)|uniprotkb:Glutamate-1-semialdehyde aminotransferase 2(gene name synonym)|uniprotkb:BA_4693(locus name)|uniprotkb:GBAA_4693(locus name)|uniprotkb:BAS4358(locus name)	psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832507|imex:IM-13779-3655	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004639(Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|rcsb pdb:3K28|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0042286""(glutamate-1-semialdehyde 2,1-aminomutase activity)|refseq:WP_001224513.1|refseq:NP_846906.1|refseq:YP_030605.1|interpro:IPR049704"	"refseq:NP_006451.1|ensembl:ENSG00000186834.4(gene)|ensembl:ENST00000332499.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0004860""(protein kinase inhibitor activity)|go:""GO:0004861""(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0007507""(heart development)|go:""GO:0017069""(snRNA binding)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0034244""(negative regulation of transcription elongation by RNA polymerase II)|go:""GO:0042802""(identical protein binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045087""(innate immune response)|go:""GO:0097322""(7SK snRNA binding)|go:""GO:0106140""(P-TEFb complex binding)|go:""GO:0120259""(7SK snRNP)|go:""GO:0140416""(transcription regulator inhibitor activity)|go:""GO:1901798""(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:2GD7|rcsb pdb:3S9G|dip:DIP-46463N|panther:PTHR13469(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:GnZPBZpKvZpcwazgpwseq6iVQbg1392	rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606	intact-crc:F536AD19293569C0|rigid:6AuZUKs0ks63GiYkuidqdHrRRxQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81QB6	uniprotkb:Q30201	intact:EBI-2813022|uniprotkb:Q6KSJ4|uniprotkb:Q6HYJ3	intact:EBI-1028850|uniprotkb:O75929|uniprotkb:O75930|uniprotkb:O75931|uniprotkb:Q17RT0|uniprotkb:Q96KU5|uniprotkb:Q96KU7|uniprotkb:Q96KU8|uniprotkb:Q9HC64|uniprotkb:Q9HC68|uniprotkb:Q9HC70|uniprotkb:Q9HC83|uniprotkb:B2CKL0|uniprotkb:Q96KU6|ensembl:ENSP00000417404.1	psi-mi:iola2_bacan(display_long)|uniprotkb:iolA2(gene name)|psi-mi:iolA2(display_short)|uniprotkb:Methylmalonate-semialdehyde dehydrogenase 2(gene name synonym)|uniprotkb:BAS2334(locus name)|uniprotkb:BA_2513(locus name)|uniprotkb:GBAA_2513(locus name)	psi-mi:hfe_human(display_long)|uniprotkb:HFE(gene name)|psi-mi:HFE(display_short)|uniprotkb:HLAH(gene name synonym)|uniprotkb:HLA-H(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832493|imex:IM-13779-3656	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR010061(Methylmalonate-semialdehyde dehydrogenase)|interpro:IPR023510|go:""GO:0004491""(""methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"")|go:""GO:0006210""(thymine catabolic process)|go:""GO:0006574""(valine catabolic process)|go:""GO:0018478""(""malonate-semialdehyde dehydrogenase (acetylating) activity"")|go:""GO:0019310""(inositol catabolic process)|refseq:WP_000218128.1|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:NP_844885.1|refseq:YP_028595.1"	"dip:DIP-2737N|efo:""Orphanet:443057""|efo:""Orphanet:443062""|efo:""Orphanet:465508""|efo:""Orphanet:586""|efo:""Orphanet:648581""|ensembl:ENSG00000010704.20(gene)|ensembl:ENST00000357618.10(transcript)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002725""(negative regulation of T cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010039""(response to iron ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0039706""(co-receptor binding)|go:""GO:0042446""(hormone biosynthetic process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045178""(basal part of cell)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0060391""(positive regulation of SMAD protein signal transduction)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0090277""(positive regulation of peptide hormone secretion)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904283""(negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990641""(response to iron ion starvation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000008""(regulation of protein localization to cell surface)|go:""GO:2000059""(negative regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000272""(negative regulation of signaling receptor activity)|go:""GO:2000273""(positive regulation of signaling receptor activity)|go:""GO:2001186""(negative regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:Q30201|rcsb pdb:1A6Z|rcsb pdb:1DE4|reactome:R-HSA-917977|refseq:NP_000401.1|refseq:NP_001287678.1|refseq:NP_620572.1|refseq:NP_620573.1|refseq:NP_620575.1|refseq:NP_620576.1|refseq:NP_620577.1|refseq:NP_620578.1|refseq:NP_620579.1|refseq:NP_620580.1|panther:PTHR16675(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TaEXSia0nVVJlDhMy7qd6AdehPI1392	rogid:YKMZhOMDbQmgnBFdI99XH9BqDp09606	intact-crc:0316FBD9CEEC340F|rigid:s1xkSxOspz1laP1nY6Q+Q26GxJk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04233	uniprotkb:A0A6L7HB03	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	intact:EBI-2828395|uniprotkb:Q6KU14|uniprotkb:Q6I035|uniprotkb:E9RDA1|uniprotkb:E9RDA2|uniprotkb:Q81RV9|uniprotkb:A0A0F7RFN3	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:a0a6l7hb03_bacan(display_long)|uniprotkb:GBAA_1928(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832474|imex:IM-13779-3657	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR010192(O-succinylbenzoate-CoA ligase)|interpro:IPR025110|refseq:WP_001161508.1|go:""GO:0005524""(ATP binding)|go:""GO:0006631""(fatty acid metabolic process)|go:""GO:0008756""(o-succinylbenzoate-CoA ligase activity)|go:""GO:0009234""(menaquinone biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0031956""(medium-chain fatty acid-CoA ligase activity)|interpro:IPR042099|interpro:IPR045851"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:BNLlm3a424mKtNl0EC/rwZDqXmw1392	intact-crc:F5409051610D352F|rigid:zIhRFWc8QIvXIA8UA3R0O6kyqrE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q30201	uniprotkb:A0A6H3AKP3	intact:EBI-1028850|uniprotkb:O75929|uniprotkb:O75930|uniprotkb:O75931|uniprotkb:Q17RT0|uniprotkb:Q96KU5|uniprotkb:Q96KU7|uniprotkb:Q96KU8|uniprotkb:Q9HC64|uniprotkb:Q9HC68|uniprotkb:Q9HC70|uniprotkb:Q9HC83|uniprotkb:B2CKL0|uniprotkb:Q96KU6|ensembl:ENSP00000417404.1	intact:EBI-2813310|uniprotkb:Q6KM94|uniprotkb:Q6HT04|uniprotkb:E9QTN5|uniprotkb:E9QTN6|uniprotkb:Q81LJ8|uniprotkb:A0A1V4BJH0	psi-mi:hfe_human(display_long)|uniprotkb:HFE(gene name)|psi-mi:HFE(display_short)|uniprotkb:HLAH(gene name synonym)|uniprotkb:HLA-H(gene name synonym)	psi-mi:a0a6h3akp3_bacan(display_long)|uniprotkb:GBAA_4618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832500|imex:IM-13779-3654	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-2737N|efo:""Orphanet:443057""|efo:""Orphanet:443062""|efo:""Orphanet:465508""|efo:""Orphanet:586""|efo:""Orphanet:648581""|ensembl:ENSG00000010704.20(gene)|ensembl:ENST00000357618.10(transcript)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002476""(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0002725""(negative regulation of T cell cytokine production)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006826""(iron ion transport)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010039""(response to iron ion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0034756""(regulation of iron ion transport)|go:""GO:0039706""(co-receptor binding)|go:""GO:0042446""(hormone biosynthetic process)|go:""GO:0045177""(apical part of cell)|go:""GO:0045178""(basal part of cell)|go:""GO:0048260""(positive regulation of receptor-mediated endocytosis)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0060391""(positive regulation of SMAD protein signal transduction)|go:""GO:0060586""(multicellular organismal-level iron ion homeostasis)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0071281""(cellular response to iron ion)|go:""GO:0090277""(positive regulation of peptide hormone secretion)|go:""GO:1900121""(negative regulation of receptor binding)|go:""GO:1900122""(positive regulation of receptor binding)|go:""GO:1904283""(negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:1904434""(positive regulation of ferrous iron binding)|go:""GO:1904437""(positive regulation of transferrin receptor binding)|go:""GO:1990459""(transferrin receptor binding)|go:""GO:1990641""(response to iron ion starvation)|go:""GO:1990712""(HFE-transferrin receptor complex)|go:""GO:2000008""(regulation of protein localization to cell surface)|go:""GO:2000059""(negative regulation of ubiquitin-dependent protein catabolic process)|go:""GO:2000272""(negative regulation of signaling receptor activity)|go:""GO:2000273""(positive regulation of signaling receptor activity)|go:""GO:2001186""(negative regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:Q30201|rcsb pdb:1A6Z|rcsb pdb:1DE4|reactome:R-HSA-917977|refseq:NP_000401.1|refseq:NP_001287678.1|refseq:NP_620572.1|refseq:NP_620573.1|refseq:NP_620575.1|refseq:NP_620576.1|refseq:NP_620577.1|refseq:NP_620578.1|refseq:NP_620579.1|refseq:NP_620580.1|panther:PTHR16675(orthology-group)"	"refseq:WP_000793108.1|interpro:IPR002549(Protein of unknown function UPF0118)|go:""GO:0016020""(membrane)|go:""GO:0055085""(transmembrane transport)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YKMZhOMDbQmgnBFdI99XH9BqDp09606	rogid:EuoKynuHXFv/xrmnc1nvaUXmtMM1392	intact-crc:BA5511999685498C|rigid:jDIDyvntX8yzcnf0An/D3cv52P0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P7E9	uniprotkb:P04233	intact:EBI-2832484|uniprotkb:Q6KTX4|uniprotkb:Q6HZZ5|uniprotkb:E9QS13|uniprotkb:E9QS14|uniprotkb:Q81RR8	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530.7	psi-mi:a0a6l8p7e9_bacan(display_long)|uniprotkb:GBAA_1972(locus name)	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832481|imex:IM-13779-3653	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR021459|refseq:WP_000738121.1	"refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582.17(gene)|ensembl:ENST00000009530.13(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001516""(prostaglandin biosynthetic process)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0002286""(T cell activation involved in immune response)|go:""GO:0002606""(positive regulation of dendritic cell antigen processing and presentation)|go:""GO:0002792""(negative regulation of peptide secretion)|go:""GO:0002830""(positive regulation of type 2 immune response)|go:""GO:0002906""(negative regulation of mature B cell apoptotic process)|go:""GO:0004896""(cytokine receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005771""(multivesicular body)|go:""GO:0005773""(vacuole)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019882""(antigen processing and presentation)|go:""GO:0019883""(antigen processing and presentation of endogenous antigen)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0019955""(cytokine binding)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031394""(positive regulation of prostaglandin biosynthetic process)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033674""(positive regulation of kinase activity)|go:""GO:0034341""(response to type II interferon)|go:""GO:0035691""(macrophage migration inhibitory factor signaling pathway)|go:""GO:0035692""(macrophage migration inhibitory factor receptor complex)|go:""GO:0035693""(NOS2-CD74 complex)|go:""GO:0035718""(macrophage migration inhibitory factor binding)|go:""GO:0042289""(MHC class II protein binding)|go:""GO:0042609""(CD4 receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0042658""(MHC class II protein binding, via antigen binding groove)|go:""GO:0042802""(identical protein binding)|go:""GO:0043030""(regulation of macrophage activation)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043518""(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045058""(T cell selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045581""(negative regulation of T cell differentiation)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0050821""(protein stabilization)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070206""(protein trimerization)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0090023""(positive regulation of neutrophil chemotaxis)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:1902166""(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000448""(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|interpro:IPR036857|interpro:IPR043530|interpro:IPR052001|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|rcsb pdb:5KSU|rcsb pdb:5KSV|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:8VSP|rcsb pdb:9CYL|rcsb pdb:9CYM|reactome:R-HSA-202733|reactome:R-HSA-2132295|panther:PTHR14093(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LdiAiRgorPRBdBtL88V7To7R72k1392	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	intact-crc:FDC8BAC888221E41|rigid:kAhIDdvmBAY7wjVdEZb+HfrJfA8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PCK7	uniprotkb:Q9UKV0	intact:EBI-2810879|uniprotkb:Q6KQA6|uniprotkb:Q6HW50|uniprotkb:E9QU09|uniprotkb:E9QU10|uniprotkb:A0A2P0HGJ3|uniprotkb:Q81MY7	intact:EBI-765444|uniprotkb:O94845|uniprotkb:O95028|uniprotkb:Q2M2R6|uniprotkb:Q86SL1|uniprotkb:Q86US3|uniprotkb:A7E2F3|ensembl:ENSP00000410337.2|uniprotkb:B7Z917|uniprotkb:B7Z4I4|uniprotkb:B7Z928|uniprotkb:B7Z940|uniprotkb:C9JS87|uniprotkb:E7EX34|uniprotkb:F8W9E0|intact:EBI-28970749	psi-mi:a0a6l8pck7_bacan(display_long)|uniprotkb:GBAA_3432(locus name)|uniprotkb:tkt1(gene name)|psi-mi:tkt1(display_short)	psi-mi:hdac9_human(display_long)|uniprotkb:Histone deacetylase 7B(gene name synonym)|uniprotkb:Histone deacetylase-related protein(gene name synonym)|uniprotkb:MEF2-interacting transcription repressor MITR(gene name synonym)|uniprotkb:HDAC9(gene name)|psi-mi:HDAC9(display_short)|uniprotkb:HDAC7(gene name synonym)|uniprotkb:HDAC7B(gene name synonym)|uniprotkb:KIAA0744(gene name synonym)|uniprotkb:HDRP(gene name synonym)|uniprotkb:MITR(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832558|imex:IM-13779-3660	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033247|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR029061|go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|refseq:WP_000193036.1|interpro:IPR049557"	"refseq:NP_001308818.1|refseq:NP_848510.1|refseq:NP_848512.1|refseq:NP_001191073.1|refseq:NP_001191074.1|refseq:NP_001191075.1|refseq:NP_001191076.1|refseq:NP_001191077.1|refseq:NP_055522.1|refseq:NP_478056.1|ensembl:ENSG00000048052.25(gene)|ensembl:ENST00000432645.6(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0001975""(response to amphetamine)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0004407""(histone deacetylase activity)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0006954""(inflammatory response)|go:""GO:0007507""(heart development)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030183""(B cell differentiation)|go:""GO:0031078""(histone H3K14 deacetylase activity, hydrolytic mechanism)|go:""GO:0032129""(histone H3K9 deacetylase activity, hydrolytic mechanism)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0033558""(protein lysine deacetylase activity)|go:""GO:0034739""(histone H4K16 deacetylase activity, hydrolytic mechanism)|go:""GO:0034983""(peptidyl-lysine deacetylation)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042113""(B cell activation)|go:""GO:0042632""(cholesterol homeostasis)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048742""(regulation of skeletal muscle fiber development)|go:""GO:0051153""(regulation of striated muscle cell differentiation)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140937""(histone H4K12 deacetylase activity, hydrolytic mechanism)|go:""GO:0180032""(histone H4K5 deacetylase activity, hydrolytic mechanism)|go:""GO:0180033""(histone H4K8 deacetylase activity, hydrolytic mechanism)|go:""GO:1990162""(histone H3K4 deacetylase activity, hydrolytic mechanism)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR037138|interpro:IPR046949|mint:Q9UKV0|rcsb pdb:8Q9N|rcsb pdb:8Q9R|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|refseq:NP_001308797.1|refseq:NP_001308798.1|refseq:NP_001308799.1|refseq:NP_001308800.1|refseq:NP_001308801.1|refseq:NP_001308802.1|refseq:NP_001308803.1|refseq:NP_001308804.1|refseq:NP_001308805.1|refseq:NP_001308806.1|refseq:NP_001308807.1|refseq:NP_001308808.1|refseq:NP_001308813.1|refseq:NP_001308814.1|refseq:NP_001308815.1|refseq:NP_001308816.1|refseq:NP_001308817.1|refseq:NP_001308819.1|refseq:NP_001308820.1|refseq:NP_001308822.1|refseq:NP_001308823.1|refseq:NP_001308824.1|refseq:NP_001308825.1|refseq:NP_001308826.1|refseq:NP_001308827.1|refseq:NP_001308828.1|refseq:NP_001308829.1|refseq:NP_001308830.1|refseq:NP_001308831.1|refseq:XP_016868315.1|refseq:XP_016868317.1|refseq:XP_011513940.1|refseq:XP_011513941.1|dip:DIP-39904N|panther:PTHR10625(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CAmYX1bWNU1J1p+yojcrnbiE0Ww1392	rogid:oFAc6CP+RY58lEB4qPxWnM90ecg9606	intact-crc:35C2DD4A3ECCCB4B|rigid:cnutNycGLat0QJgZmRjloqrD8FQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HG64	uniprotkb:Q14469	intact:EBI-2814113|uniprotkb:Q6HVM1|uniprotkb:Q6KPT8|uniprotkb:E9QWJ5|uniprotkb:E9QWJ6|uniprotkb:Q81YC9	intact:EBI-2832522|uniprotkb:Q6FHB2|ensembl:ENSP00000232424.3	psi-mi:a0a6l7hg64_bacan(display_long)|uniprotkb:moeA2(gene name)|psi-mi:moeA2(display_short)|uniprotkb:GBAA_3623(locus name)	psi-mi:hes1_human(display_long)|uniprotkb:HES1(gene name)|psi-mi:HES1(display_short)|uniprotkb:BHLHB39(gene name synonym)|uniprotkb:HL(gene name synonym)|uniprotkb:HRY(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 39(gene name synonym)|uniprotkb:Hairy and enhancer of split 1(gene name synonym)|uniprotkb:Hairy homolog(gene name synonym)|uniprotkb:Hairy-like protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832519|imex:IM-13779-3658	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005111(MoeA, C-terminal, domain IV)|interpro:IPR005110(MoeA, N-terminal, domain I and II)|interpro:IPR001453(Molybdopterin binding)|interpro:IPR038987|go:""GO:0005829""(cytosol)|go:""GO:0006777""(Mo-molybdopterin cofactor biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0061599""(molybdopterin molybdotransferase activity)|refseq:WP_000442182.1|interpro:IPR036135|interpro:IPR036425|interpro:IPR036688"	"refseq:NP_005515.1|ensembl:ENSG00000114315.4(gene)|ensembl:ENST00000232424.4(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001709""(cell fate determination)|go:""GO:0001889""(liver development)|go:""GO:0003143""(embryonic heart tube morphogenesis)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003266""(regulation of secondary heart field cardioblast proliferation)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003310""(pancreatic A cell differentiation)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007155""(cell adhesion)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0009952""(anterior/posterior pattern specification)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0014070""(obsolete response to organic cyclic compound)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0021537""(telencephalon development)|go:""GO:0021555""(midbrain-hindbrain boundary morphogenesis)|go:""GO:0021557""(oculomotor nerve development)|go:""GO:0021558""(trochlear nerve development)|go:""GO:0021575""(hindbrain morphogenesis)|go:""GO:0021861""(forebrain radial glial cell differentiation)|go:""GO:0021870""(Cajal-Retzius cell differentiation)|go:""GO:0021984""(adenohypophysis development)|go:""GO:0030324""(lung development)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0030901""(midbrain development)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0035881""(amacrine cell differentiation)|go:""GO:0035910""(ascending aorta morphogenesis)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042102""(positive regulation of T cell proliferation)|go:""GO:0042491""(inner ear auditory receptor cell differentiation)|go:""GO:0042531""(positive regulation of tyrosine phosphorylation of STAT protein)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0043279""(response to alkaloid)|go:""GO:0043388""(positive regulation of DNA binding)|go:""GO:0043398""(HLH domain binding)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045598""(regulation of fat cell differentiation)|go:""GO:0045608""(negative regulation of inner ear auditory receptor cell differentiation)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045977""(positive regulation of mitotic cell cycle, embryonic)|go:""GO:0046331""(lateral inhibition)|go:""GO:0046425""(regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0048469""(cell maturation)|go:""GO:0048538""(thymus development)|go:""GO:0048667""(cell morphogenesis involved in neuron differentiation)|go:""GO:0048711""(positive regulation of astrocyte differentiation)|go:""GO:0048715""(negative regulation of oligodendrocyte differentiation)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0050678""(regulation of epithelial cell proliferation)|go:""GO:0050767""(regulation of neurogenesis)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0060122""(inner ear receptor cell stereocilium organization)|go:""GO:0060164""(regulation of timing of neuron differentiation)|go:""GO:0060253""(negative regulation of glial cell proliferation)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060675""(ureteric bud morphogenesis)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0061009""(common bile duct development)|go:""GO:0061102""(stomach neuroendocrine cell differentiation)|go:""GO:0061106""(negative regulation of stomach neuroendocrine cell differentiation)|go:""GO:0061309""(cardiac neural crest cell development involved in outflow tract morphogenesis)|go:""GO:0061626""(pharyngeal arch artery morphogenesis)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070888""(E-box binding)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071398""(cellular response to fatty acid)|go:""GO:0071820""(N-box binding)|go:""GO:0072012""(glomerulus vasculature development)|go:""GO:0072049""(comma-shaped body morphogenesis)|go:""GO:0072050""(S-shaped body morphogenesis)|go:""GO:0072141""(renal interstitial fibroblast development)|go:""GO:0072282""(metanephric nephron tubule morphogenesis)|go:""GO:0090102""(cochlea development)|go:""GO:0090162""(establishment of epithelial cell polarity)|go:""GO:0090281""(negative regulation of calcium ion import)|go:""GO:0097066""(response to thyroid hormone)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:1902870""(negative regulation of amacrine cell differentiation)|go:""GO:1905934""(negative regulation of cell fate determination)|go:""GO:1990090""(cellular response to nerve growth factor stimulus)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000227""(negative regulation of pancreatic A cell differentiation)|go:""GO:2000737""(negative regulation of stem cell differentiation)|go:""GO:2000974""(negative regulation of pro-B cell differentiation)|go:""GO:2000978""(negative regulation of forebrain neuron differentiation)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR050370|mint:Q14469|rcsb pdb:2MH3|rcsb pdb:7C4O|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-8940973|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|panther:PTHR10985(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:C96t9o6mRnooPEG8+QR/AdX4ktU1392	rogid:OBG5Ej5tF/GSXLChM9hXAe7Frwk9606	intact-crc:5B9D21F2D922919F|rigid:jDv8j5z7CucjHp9BdIBCV78Apbc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H583	uniprotkb:A0A348A0Q7	intact:EBI-1048716|uniprotkb:Q5T3Q8|uniprotkb:Q6P197|uniprotkb:Q9NW23|ensembl:ENSP00000355541.3	intact:EBI-2813755|uniprotkb:Q6I205|uniprotkb:Q6KVU3|uniprotkb:E9QSR2|uniprotkb:E9QSR3|uniprotkb:Q81TS2|uniprotkb:A0A0J1I2N1	psi-mi:heat1_human(display_long)|uniprotkb:Protein BAP28(gene name synonym)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)|uniprotkb:BAP28(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 10 homolog(gene name synonym)|uniprotkb:UTP10(gene name synonym)	psi-mi:a0a348a0q7_bacan(display_long)|uniprotkb:GBAA_1193(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832551|imex:IM-13779-3662	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060542.4|ensembl:ENSG00000119285.11(gene)|ensembl:ENST00000366582.8(transcript)|go:""GO:0000462""(""maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0001650""(fibrillar center)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005739""(mitochondrion)|go:""GO:0016020""(membrane)|go:""GO:0016072""(rRNA metabolic process)|go:""GO:0030515""(snoRNA binding)|go:""GO:0030686""(90S preribosome)|go:""GO:0032040""(small-subunit processome)|go:""GO:0034455""(t-UTP complex)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0045943""(positive regulation of transcription by RNA polymerase I)|go:""GO:0061351""(neural precursor cell proliferation)|go:""GO:1902570""(protein localization to nucleolus)|go:""GO:2000234""(positive regulation of rRNA processing)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022125|interpro:IPR040191|mint:Q9H583|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|reactome:R-HSA-6790901|reactome:R-HSA-6791226|panther:PTHR13457(orthology-group)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|interpro:IPR025966|interpro:IPR050366|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|go:""GO:0015833""(peptide transport)|go:""GO:0055085""(transmembrane transport)|refseq:WP_000974102.1|interpro:IPR035906"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0WoP84UUVfXWppmvCYa/n5GTzc89606	rogid:B3zpo7vCxGbwbsjvdBVCOUXvS381392	intact-crc:FA7588C0567A4456|rigid:GCRLiZ98Z8iYJot+RPD2yp+/uMw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AK62	uniprotkb:P42694	intact:EBI-2819328|uniprotkb:Q6HXU0|uniprotkb:Q6F0B1|uniprotkb:E9QQR1|uniprotkb:E9QQR2|uniprotkb:Q81PM5|uniprotkb:A0A0J1I503	intact:EBI-1210654|uniprotkb:I6L9H4|ensembl:ENSP00000351524.5	psi-mi:a0a6h3ak62_bacan(display_long)|uniprotkb:GBAA_2777(locus name)	psi-mi:helz_human(display_long)|uniprotkb:HELZ(gene name)|psi-mi:HELZ(display_short)|uniprotkb:KIAA0054(gene name synonym)|uniprotkb:DRHC(gene name synonym)|uniprotkb:Down-regulated in human cancers protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832531|imex:IM-13779-3661	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR024775|refseq:WP_000951606.1|interpro:IPR034660	"refseq:NP_055692.2|ensembl:ENSG00000198265.12(gene)|ensembl:ENST00000358691.10(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0016020""(membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0035194""(regulatory ncRNA-mediated post-transcriptional gene silencing)|go:""GO:0043186""(P granule)|go:""GO:0046872""(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR027417|interpro:IPR036855|interpro:IPR041677|interpro:IPR041679|interpro:IPR045055|interpro:IPR047187|interpro:IPR049569|mint:P42694|dip:DIP-39352N|panther:PTHR10887(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/17	rogid:YnVcYRCZvvAwyrzaAZ749odtFvY1392	rogid:q+2P+W7RDRl2CyPhdEsvONGaM0U9606	intact-crc:9849DFB77C511F8F|rigid:PnTmNztyfk+6c5Mdsj95VVGi8Ho	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A1V4BJ25	uniprotkb:Q8N3C0	intact:EBI-2832538|uniprotkb:Q6KM27|uniprotkb:Q6HST4|uniprotkb:E9QYA6|uniprotkb:E9QYA7|uniprotkb:Q81LD1	intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159.2	psi-mi:a0a1v4bj25_bacan(display_long)|uniprotkb:GBAA_4692(locus name)	psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832544|imex:IM-13779-3659	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR018392|interpro:IPR014256(Sporulation stage VI, protein D)|interpro:IPR036779|interpro:IPR048862	"refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249.14(gene)|ensembl:ENST00000369162.7(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006307""(DNA alkylation repair)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0022626""(cytosolic ribosome)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0032790""(ribosome disassembly)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0043138""(3'-5' DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0099053""(obsolete activating signal cointegrator 1 complex)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990116""(ribosome-associated ubiquitin-dependent protein catabolic process)|go:""GO:1990391""(DNA repair complex)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR050474|mint:Q8N3C0|rcsb pdb:6YXQ|rcsb pdb:8ALZ|reactome:R-HSA-112126|panther:PTHR24075(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1/DWG2hNiypEZJFNJWa4zH2Rw9w1392	rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606	intact-crc:6112818CFE80DBD7|rigid:wmXIP9EzfyXKdL7pE5lswBUYZFE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81JW1	uniprotkb:P56524	intact:EBI-2816384|uniprotkb:Q6KJT7|uniprotkb:Q6HQG2	intact:EBI-308629|uniprotkb:Q9UND6|intact:EBI-28970476|ensembl:ENSP00000264606.3|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7	psi-mi:pyrg_bacan(display_long)|uniprotkb:pyrG(gene name)|psi-mi:pyrG(display_short)|uniprotkb:ctrA(gene name synonym)|uniprotkb:UTP--ammonia ligase(gene name synonym)|uniprotkb:BA_5583(locus name)|uniprotkb:GBAA_5583(locus name)|uniprotkb:BAS5187(locus name)|uniprotkb:Cytidine 5'-triphosphate synthase(gene name synonym)|uniprotkb:Cytidine triphosphate synthetase(gene name synonym)	psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832565|imex:IM-13779-3667	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR029062|interpro:IPR027417|go:""GO:0003883""(CTP synthase activity)|go:""GO:0004359""(glutaminase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019856""(pyrimidine nucleobase biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0044210""('de novo' CTP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000170456.1|interpro:IPR033828|refseq:NP_847739.1|refseq:YP_031426.1"	"efo:""Orphanet:1001""|ensembl:ENSG00000068024.18(gene)|ensembl:ENST00000345617.7(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0004407""(histone deacetylase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006476""(protein deacetylation)|go:""GO:0006954""(inflammatory response)|go:""GO:0007399""(nervous system development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0010832""(negative regulation of myotube differentiation)|go:""GO:0010944""(negative regulation of transcription by competitive promoter binding)|go:""GO:0014894""(response to denervation involved in regulation of muscle adaptation)|go:""GO:0014898""(cardiac muscle hypertrophy in response to stress)|go:""GO:0016607""(nuclear speck)|go:""GO:0016925""(protein sumoylation)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019789""(SUMO transferase activity)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030955""(potassium ion binding)|go:""GO:0031078""(histone H3K14 deacetylase activity, hydrolytic mechanism)|go:""GO:0032129""(histone H3K9 deacetylase activity, hydrolytic mechanism)|go:""GO:0033235""(positive regulation of protein sumoylation)|go:""GO:0033558""(protein lysine deacetylase activity)|go:""GO:0034739""(histone H4K16 deacetylase activity, hydrolytic mechanism)|go:""GO:0034983""(peptidyl-lysine deacetylation)|go:""GO:0042113""(B cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0043393""(regulation of protein binding)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0045820""(negative regulation of glycolytic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140937""(histone H4K12 deacetylase activity, hydrolytic mechanism)|go:""GO:0180032""(histone H4K5 deacetylase activity, hydrolytic mechanism)|go:""GO:0180033""(histone H4K8 deacetylase activity, hydrolytic mechanism)|go:""GO:1990162""(histone H3K4 deacetylase activity, hydrolytic mechanism)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR037138|interpro:IPR046949|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|rcsb pdb:7XUZ|rcsb pdb:8PDE|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N|panther:PTHR10625(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/28	rogid:SrGr2YO98Kx1ur7cTIL31MeRXwk1392	rogid:EJhE8LikofmF9H8ubNsola4pSpc9606	intact-crc:8AAA4E443FC616B8|rigid:Sr9mE/JOYNGE4P2QpI9nnMr0iTk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9RMZ3	uniprotkb:Q9Y5Z7	intact:EBI-2820320|uniprotkb:A0A6L7HBM1	intact:EBI-592728|ensembl:ENSP00000229330.4|uniprotkb:B2R8Q5|uniprotkb:C0H5X3	psi-mi:q9rmz3_bacan(display_long)|uniprotkb:capR(gene name)|psi-mi:capR(display_short)|uniprotkb:GBAA_pXO2_0040(locus name)	psi-mi:hcfc2_human(display_long)|uniprotkb:C2 factor(gene name synonym)|uniprotkb:HCFC2(gene name)|psi-mi:HCFC2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832586|imex:IM-13779-3664	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000400406.1|refseq:NP_053194.1|interpro:IPR025669|interpro:IPR027417|interpro:IPR050678	"ensembl:ENSG00000111727.12(gene)|ensembl:ENST00000229330.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016032""(viral process)|go:""GO:0016604""(nuclear body)|go:""GO:0034139""(regulation of toll-like receptor 3 signaling pathway)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0071339""(MLL1 complex)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1902615""(immune response involved in response to exogenous dsRNA)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR043536|mint:Q9Y5Z7|reactome:R-HSA-9772755|refseq:NP_037452.1|panther:PTHR46003(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aAYoIttBfJ51/60pEmBMu1KAreU1392	rogid:ytE7Aid9JO9RWsRpJPpBbylLRXo9606	intact-crc:87AC2596A9220D59|rigid:SpFUPV6+jeuQwspPdXCszawAO0M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8NVB0	uniprotkb:O15379	intact:EBI-2811493|uniprotkb:Q6KWL2|uniprotkb:Q6I2T1|uniprotkb:E9R8N8|uniprotkb:E9R8N9|uniprotkb:Q81UK2|uniprotkb:A0A0F7RLK2	intact:EBI-607682|uniprotkb:O43268|uniprotkb:Q9UEI5|uniprotkb:Q9UEV0|uniprotkb:D3DQE1|ensembl:ENSP00000302967.3	psi-mi:a0a6l8nvb0_bacan(display_long)|uniprotkb:alsS(gene name)|psi-mi:alsS(display_short)|uniprotkb:GBAA_0866(locus name)	psi-mi:hdac3_human(display_long)|uniprotkb:HDAC3(gene name)|psi-mi:HDAC3(display_short)|uniprotkb:Protein deacetylase HDAC3(gene name synonym)|uniprotkb:Protein deacylase HDAC3(gene name synonym)|uniprotkb:RPD3-2(gene name synonym)|uniprotkb:SMAP45(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832572|imex:IM-13779-3663	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012782(Acetolactate synthase, catabolic)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR029035|interpro:IPR029061|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003984""(acetolactate synthase activity)|go:""GO:0005948""(acetolactate synthase complex)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0034077""(butanediol metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_000103511.1|interpro:IPR045229"	"refseq:NP_003874.2|ensembl:ENSG00000171720.10(gene)|ensembl:ENST00000305264.8(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000785""(chromatin)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0004407""(histone deacetylase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006325""(chromatin organization)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006476""(protein deacetylation)|go:""GO:0007346""(regulation of mitotic cell cycle)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019899""(enzyme binding)|go:""GO:0030332""(cyclin binding)|go:""GO:0031078""(histone H3K14 deacetylase activity, hydrolytic mechanism)|go:""GO:0031398""(positive regulation of protein ubiquitination)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032008""(positive regulation of TOR signaling)|go:""GO:0032129""(histone H3K9 deacetylase activity, hydrolytic mechanism)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0033558""(protein lysine deacetylase activity)|go:""GO:0034739""(histone H4K16 deacetylase activity, hydrolytic mechanism)|go:""GO:0040014""(regulation of multicellular organism growth)|go:""GO:0040029""(epigenetic regulation of gene expression)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042903""(tubulin deacetylase activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0060816""(random inactivation of X chromosome)|go:""GO:0061351""(neural precursor cell proliferation)|go:""GO:0061436""(establishment of skin barrier)|go:""GO:0071498""(cellular response to fluid shear stress)|go:""GO:0072686""(mitotic spindle)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140861""(DNA repair-dependent chromatin remodeling)|go:""GO:0140937""(histone H4K12 deacetylase activity, hydrolytic mechanism)|go:""GO:0160008""(protein decrotonylase activity)|go:""GO:0160009""(histone decrotonylase activity)|go:""GO:0160010""(protein de-2-hydroxyisobutyrylase activity)|go:""GO:0160216""(protein lysine delactylase activity)|go:""GO:0180032""(histone H4K5 deacetylase activity, hydrolytic mechanism)|go:""GO:0180033""(histone H4K8 deacetylase activity, hydrolytic mechanism)|go:""GO:1903575""(cornified envelope assembly)|go:""GO:1990162""(histone H3K4 deacetylase activity, hydrolytic mechanism)|go:""GO:2000726""(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|interpro:IPR050284|mint:O15379|rcsb pdb:4A69|reactome:R-HSA-1368071|reactome:R-HSA-193670|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-390471|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9701898|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9841922|dip:DIP-24253N|panther:PTHR10625(orthology-group)|ensembl:ENSP00000302967.3"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/13	rogid:rRCMmJc9HuwjVl3UsPYv6jvntSI1392	rogid:X5pnE98s15eXKev3nauN7ri5kqg9606	intact-crc:EE0B399335729258|rigid:2EeR+SaclMN6BsEWlKCSB/Vg6Kg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5I8	uniprotkb:Q13547	intact:EBI-2820109|uniprotkb:Q6HY62|uniprotkb:Q6KS76|uniprotkb:E9QSG7|uniprotkb:E9QSG8|uniprotkb:Q81PZ2|uniprotkb:A0A0J1I4S2	intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649.3	psi-mi:a0a6l7h5i8_bacan(display_long)|uniprotkb:GBAA_2647(locus name)	psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym)|uniprotkb:Protein deacetylase HDAC1(gene name synonym)|uniprotkb:Protein deacylase HDAC1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832579|imex:IM-13779-3666	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000644533.1|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR011032(GroES-like)|interpro:IPR020843|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR052711|interpro:IPR036291"	"refseq:NP_004955.2|ensembl:ENSG00000116478.13(gene)|ensembl:ENST00000373548.8(transcript)|go:""GO:0000118""(histone deacetylase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000792""(heterochromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0002039""(p53 binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0004407""(histone deacetylase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006346""(DNA methylation-dependent constitutive heterochromatin formation)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006476""(protein deacetylation)|go:""GO:0007492""(endoderm development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009913""(epidermal cell differentiation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016581""(NuRD complex)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019899""(enzyme binding)|go:""GO:0021766""(hippocampus development)|go:""GO:0030182""(neuron differentiation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031078""(histone H3K14 deacetylase activity, hydrolytic mechanism)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0032129""(histone H3K9 deacetylase activity, hydrolytic mechanism)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033558""(protein lysine deacetylase activity)|go:""GO:0034739""(histone H4K16 deacetylase activity, hydrolytic mechanism)|go:""GO:0035851""(Krueppel-associated box domain binding)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042659""(regulation of cell fate specification)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0042826""(histone deacetylase binding)|go:""GO:0042903""(tubulin deacetylase activity)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043922""(negative regulation by host of viral transcription)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0060789""(hair follicle placode formation)|go:""GO:0061029""(eyelid development in camera-type eye)|go:""GO:0061198""(fungiform papilla formation)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070822""(Sin3-type complex)|go:""GO:0070888""(E-box binding)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140937""(histone H4K12 deacetylase activity, hydrolytic mechanism)|go:""GO:0160009""(histone decrotonylase activity)|go:""GO:0160216""(protein lysine delactylase activity)|go:""GO:0180032""(histone H4K5 deacetylase activity, hydrolytic mechanism)|go:""GO:0180033""(histone H4K8 deacetylase activity, hydrolytic mechanism)|go:""GO:1902455""(negative regulation of stem cell population maintenance)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:1990162""(histone H3K4 deacetylase activity, hydrolytic mechanism)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000273""(positive regulation of signaling receptor activity)|go:""GO:2000736""(regulation of stem cell differentiation)|go:""GO:2001243""(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|interpro:IPR050284|mint:Q13547|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|rcsb pdb:7SME|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-9701898|reactome:R-HSA-9725371|reactome:R-HSA-9824594|reactome:R-HSA-9825892|reactome:R-HSA-983231|reactome:R-HSA-9843940|reactome:R-HSA-9844594|reactome:R-HSA-9845323|reactome:R-HSA-9856649|dip:DIP-24184N|ensembl:ENSP00000362649.3|panther:PTHR10625(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:MAC3CsiJ5bB1Sm1kgUwJzzfeKIY1392	rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606	intact-crc:F561FB666FAA0219|rigid:b66LWvN2qxgeNADsFbCy+Xe67Wo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HNX5	uniprotkb:P51610	intact:EBI-2813143|uniprotkb:Q6KWX9|uniprotkb:Q6I360|uniprotkb:E9QY78|uniprotkb:E9QY79|uniprotkb:A0A2P0HA93|uniprotkb:Q81UX8	intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|ensembl:ENSP00000309555.7|intact:EBI-14324845|intact:EBI-12980473	psi-mi:a0a6l7hnx5_bacan(display_long)|uniprotkb:GBAA_0728(locus name)	psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832593|imex:IM-13779-3665	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015168(NMT1/THI5 like)|interpro:IPR027939|go:""GO:0009228""(thiamine biosynthetic process)|refseq:WP_000670426.1"	"ensembl:ENSG00000172534.14(gene)|ensembl:ENST00000310441.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0019046""(release from viral latency)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0044545""(NSL complex)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0050821""(protein stabilization)|go:""GO:0071339""(MLL1 complex)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-9772755|refseq:NP_005325.2|refseq:XP_006724879.1|efo:""Orphanet:369962""|efo:""Orphanet:777""|dip:DIP-32955N|panther:PTHR46003(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EwiLGJeG/7Y619H/Meru5ccTc801392	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	intact-crc:956CC1A3FAC902CB|rigid:YAQcOKArnuT6M9DJV9yangBplSk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AIP5	uniprotkb:P51610	intact:EBI-2818250|uniprotkb:Q6KMP9|uniprotkb:Q6HTF6|uniprotkb:E9R5H6|uniprotkb:E9R5H7|uniprotkb:Q81M04|uniprotkb:A0A0J1HYD0	intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|ensembl:ENSP00000309555.7|intact:EBI-14324845|intact:EBI-12980473	psi-mi:a0a6h3aip5_bacan(display_long)|uniprotkb:GBAA_4451(locus name)	psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832634|imex:IM-13779-3669	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001183959.1|interpro:IPR024562	"ensembl:ENSG00000172534.14(gene)|ensembl:ENST00000310441.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0019046""(release from viral latency)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0044545""(NSL complex)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0050821""(protein stabilization)|go:""GO:0071339""(MLL1 complex)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-9772755|refseq:NP_005325.2|refseq:XP_006724879.1|efo:""Orphanet:369962""|efo:""Orphanet:777""|dip:DIP-32955N|panther:PTHR46003(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:38Fp/3u/h/g7kb67glNPXKCJCes1392	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	intact-crc:31E13BD954489F3B|rigid:sEXFeutHldn/uFrGWao0R3AXOQg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P69905	uniprotkb:A0A4Y1WAR4	intact:EBI-714680|uniprotkb:P01922|uniprotkb:Q3MIF5|uniprotkb:Q96KF1|uniprotkb:Q9NYR7|uniprotkb:Q1HDT5|uniprotkb:Q53F97|uniprotkb:Q9UCM0|ensembl:ENSP00000251595.6|ensembl:ENSP00000322421.5	intact:EBI-2832614|uniprotkb:Q6HR10|uniprotkb:Q6KKC9|uniprotkb:E9QY06|uniprotkb:E9QY07|uniprotkb:Q81X74|uniprotkb:A0A0J1HQ93|uniprotkb:A0A348AC26	psi-mi:hba_human(display_long)|uniprotkb:Hemoglobin alpha chain(gene name synonym)|uniprotkb:Alpha-globin(gene name synonym)|uniprotkb:HBA1(gene name)|psi-mi:HBA1(display_short)|uniprotkb:HBA2(gene name)|psi-mi:HBA2(display_short)	psi-mi:a0a4y1war4_bacan(display_long)|uniprotkb:gap2(gene name)|psi-mi:gap2(display_short)|uniprotkb:GBAA_5369(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832620|imex:IM-13779-3671	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J3Z|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1SHR|rcsb pdb:1SI4|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|rcsb pdb:1XZ2|rcsb pdb:1XZ4|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y01|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|ensembl:ENSG00000188536.13(gene)|ensembl:ENSG00000206172.8(gene)|ensembl:ENST00000251595.11(transcript)|ensembl:ENST00000320868.9(transcript)|go:""GO:0005344""(oxygen carrier activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005833""(hemoglobin complex)|go:""GO:0015670""(carbon dioxide transport)|go:""GO:0015671""(oxygen transport)|go:""GO:0016020""(membrane)|go:""GO:0019825""(oxygen binding)|go:""GO:0020037""(heme binding)|go:""GO:0030185""(nitric oxide transport)|go:""GO:0031838""(haptoglobin-hemoglobin complex)|go:""GO:0042542""(response to hydrogen peroxide)|rcsb pdb:1Y45|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0043177""(organic acid binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0072562""(blood microparticle)|go:""GO:0098869""(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR050056|mint:P69905|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|rcsb pdb:1A3O|rcsb pdb:1A9W|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FDH|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|rcsb pdb:1YVQ|rcsb pdb:1YVT|rcsb pdb:1YZI|rcsb pdb:1Z8U|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3HXN|rcsb pdb:3IA3|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3OVU|rcsb pdb:4MQG|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S48|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4MQJ|rcsb pdb:4MQK|rcsb pdb:4N7N|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:4N8T|rcsb pdb:4NI0|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4ROM|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6HAL|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:6KAU|rcsb pdb:6KAV|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEU|rcsb pdb:7AEV|rcsb pdb:7CUE|rcsb pdb:7DY3|rcsb pdb:7DY4|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|rcsb pdb:7JY3|rcsb pdb:7K4M|rcsb pdb:8EGI|rcsb pdb:7PCF|rcsb pdb:7PCH|rcsb pdb:7PCQ|rcsb pdb:7QU4|rcsb pdb:7UD7|rcsb pdb:7UD8|rcsb pdb:7UF6|rcsb pdb:7UF7|rcsb pdb:7UVB|rcsb pdb:7VDE|rcsb pdb:7XGY|rcsb pdb:8DOV|rcsb pdb:8FDK|rcsb pdb:8FDL|rcsb pdb:8FDM|rcsb pdb:8FDN|rcsb pdb:8VYL|rcsb pdb:8WJ0|rcsb pdb:8WJ1|rcsb pdb:8WJ2|rcsb pdb:8WXW|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:NP_000508.1|refseq:NP_000549.1|dip:DIP-35199N|efo:""Orphanet:163596""|efo:""Orphanet:247511""|efo:""Orphanet:330041""|efo:""Orphanet:93616""|efo:""Orphanet:98791""|panther:PTHR11442(orthology-group)"	"interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|refseq:WP_000161236.1|go:""GO:0002020""(protease binding)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0044542""(symbiont-mediated activation of host plasminogen)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:M4o0FF1DIrouBdyFXr4UtAlcjZw9606	rogid:0d8q3Y4FUwK4Iv4Qkl7Nic6MPFM1392	intact-crc:445560158000D89E|rigid:loXK89wxK3gpr1reyhcamIdpgvE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P51610	uniprotkb:A0A6L8PX73	intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|ensembl:ENSP00000309555.7|intact:EBI-14324845|intact:EBI-12980473	intact:EBI-2814460|uniprotkb:Q6HTD2|uniprotkb:Q6KMM4|uniprotkb:E9R6D4|uniprotkb:E9R6D5|uniprotkb:Q81LY0|uniprotkb:A0A0J1HYA4	psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym)	psi-mi:a0a6l8px73_bacan(display_long)|uniprotkb:GBAA_4479(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832600|imex:IM-13779-3668	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000172534.14(gene)|ensembl:ENST00000310441.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0019046""(release from viral latency)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043254""(regulation of protein-containing complex assembly)|go:""GO:0044545""(NSL complex)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0045296""(cadherin binding)|go:""GO:0045787""(positive regulation of cell cycle)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048188""(Set1C/COMPASS complex)|go:""GO:0050821""(protein stabilization)|go:""GO:0071339""(MLL1 complex)|go:""GO:0140297""(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-9772755|refseq:NP_005325.2|refseq:XP_006724879.1|efo:""Orphanet:369962""|efo:""Orphanet:777""|dip:DIP-32955N|panther:PTHR46003(orthology-group)"	"interpro:IPR003171(Methylenetetrahydrofolate reductase)|interpro:IPR003726(Homocysteine S-methyltransferase)|interpro:IPR050554|interpro:IPR029041|go:""GO:0004489""(""methylenetetrahydrofolate reductase (NAD(P)H) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0008705""(methionine synthase activity)|go:""GO:0032259""(methylation)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|refseq:WP_000770331.1|interpro:IPR036589"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	rogid:kwYps3uM+vfuLmFjfNZe8XCRW/U1392	intact-crc:2A06C9B4AF047454|rigid:ed/YKwznOON1jjU2C9YE0yDloqg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P69905	uniprotkb:A0A348A7I7	intact:EBI-714680|uniprotkb:P01922|uniprotkb:Q3MIF5|uniprotkb:Q96KF1|uniprotkb:Q9NYR7|uniprotkb:Q1HDT5|uniprotkb:Q53F97|uniprotkb:Q9UCM0|ensembl:ENSP00000251595.6|ensembl:ENSP00000322421.5	intact:EBI-2828826|uniprotkb:Q6KPL6|uniprotkb:E9QZ63|uniprotkb:Q81Y52	psi-mi:hba_human(display_long)|uniprotkb:Hemoglobin alpha chain(gene name synonym)|uniprotkb:Alpha-globin(gene name synonym)|uniprotkb:HBA1(gene name)|psi-mi:HBA1(display_short)|uniprotkb:HBA2(gene name)|psi-mi:HBA2(display_short)	psi-mi:a0a348a7i7_bacan(display_long)|uniprotkb:GBAA_3705(locus name)|uniprotkb:Proline permease(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832607|imex:IM-13779-3670	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J3Z|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1SHR|rcsb pdb:1SI4|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|rcsb pdb:1XZ2|rcsb pdb:1XZ4|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y01|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|ensembl:ENSG00000188536.13(gene)|ensembl:ENSG00000206172.8(gene)|ensembl:ENST00000251595.11(transcript)|ensembl:ENST00000320868.9(transcript)|go:""GO:0005344""(oxygen carrier activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005833""(hemoglobin complex)|go:""GO:0015670""(carbon dioxide transport)|go:""GO:0015671""(oxygen transport)|go:""GO:0016020""(membrane)|go:""GO:0019825""(oxygen binding)|go:""GO:0020037""(heme binding)|go:""GO:0030185""(nitric oxide transport)|go:""GO:0031838""(haptoglobin-hemoglobin complex)|go:""GO:0042542""(response to hydrogen peroxide)|rcsb pdb:1Y45|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0043177""(organic acid binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0072562""(blood microparticle)|go:""GO:0098869""(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR050056|mint:P69905|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|rcsb pdb:1A3O|rcsb pdb:1A9W|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FDH|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|rcsb pdb:1YVQ|rcsb pdb:1YVT|rcsb pdb:1YZI|rcsb pdb:1Z8U|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3HXN|rcsb pdb:3IA3|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3OVU|rcsb pdb:4MQG|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S48|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4MQJ|rcsb pdb:4MQK|rcsb pdb:4N7N|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:4N8T|rcsb pdb:4NI0|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4ROM|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6HAL|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:6KAU|rcsb pdb:6KAV|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEU|rcsb pdb:7AEV|rcsb pdb:7CUE|rcsb pdb:7DY3|rcsb pdb:7DY4|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|rcsb pdb:7JY3|rcsb pdb:7K4M|rcsb pdb:8EGI|rcsb pdb:7PCF|rcsb pdb:7PCH|rcsb pdb:7PCQ|rcsb pdb:7QU4|rcsb pdb:7UD7|rcsb pdb:7UD8|rcsb pdb:7UF6|rcsb pdb:7UF7|rcsb pdb:7UVB|rcsb pdb:7VDE|rcsb pdb:7XGY|rcsb pdb:8DOV|rcsb pdb:8FDK|rcsb pdb:8FDL|rcsb pdb:8FDM|rcsb pdb:8FDN|rcsb pdb:8VYL|rcsb pdb:8WJ0|rcsb pdb:8WJ1|rcsb pdb:8WJ2|rcsb pdb:8WXW|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:NP_000508.1|refseq:NP_000549.1|dip:DIP-35199N|efo:""Orphanet:163596""|efo:""Orphanet:247511""|efo:""Orphanet:330041""|efo:""Orphanet:93616""|efo:""Orphanet:98791""|panther:PTHR11442(orthology-group)"	"refseq:WP_000687602.1|interpro:IPR011851(Sodium/proline symporter)|interpro:IPR001734(Na+/solute symporter)|go:""GO:0005298""(""proline:sodium symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0015193""(L-proline transmembrane transporter activity)|go:""GO:0015824""(proline transport)|go:""GO:0031402""(sodium ion binding)|interpro:IPR038377|interpro:IPR050277"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:M4o0FF1DIrouBdyFXr4UtAlcjZw9606	rogid:LLobNlKL5xnTjt7Je8e1G54+0HY1392	intact-crc:DAC9130FB5B05366|rigid:uUWouKDLxP+x+JOAl2VcIkRzKDA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3ACS9	uniprotkb:O00165	intact:EBI-2814882|uniprotkb:Q6KV63|uniprotkb:Q6I1B6|uniprotkb:E9QYN4|uniprotkb:E9QYN5|uniprotkb:Q81T34|uniprotkb:A0A1J9X5W3	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	psi-mi:a0a6h3acs9_bacan(display_long)|uniprotkb:GBAA_1455(locus name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832676|imex:IM-13779-3674	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016975(Cell wall-active antibiotics response protein)|interpro:IPR024425|go:""GO:0016020""(membrane)|refseq:WP_000716089.1|interpro:IPR047793"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:fV43h9v5A+fRWbvEqGpUE9xQYhw1392	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	intact-crc:1C5B91DF4492D100|rigid:UWaM7IDKC99SX6PLc4STREaTYNw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00165	uniprotkb:Q81WU4	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	intact:EBI-2830714|uniprotkb:Q6KP72|uniprotkb:Q6HUZ7	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:pept_bacan(display_long)|uniprotkb:pepT(gene name)|psi-mi:pepT(display_short)|uniprotkb:pepT-1(gene name synonym)|uniprotkb:Aminotripeptidase(gene name synonym)|uniprotkb:Tripeptide aminopeptidase(gene name synonym)|uniprotkb:BA_3872(locus name)|uniprotkb:GBAA_3872(locus name)|uniprotkb:BAS3588(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832648|imex:IM-13779-3675	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR010161(Peptidase M20B, tripeptide aminopeptidase)|rcsb pdb:3IFE|refseq:WP_000656974.1|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0045148""(tripeptide aminopeptidase activity)|interpro:IPR036264|refseq:NP_846121.1|refseq:YP_029841.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rogid:Oha1BGkI+0d8YvKh6DtzsAuCnYs1392	intact-crc:5506EC98F55246AF|rigid:ZO1XUsG4V6CfrNKDQvOUL5dtOPo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1WB04	uniprotkb:O00165	intact:EBI-2812076|uniprotkb:Q6KK37|uniprotkb:Q6HQR9|uniprotkb:E9R296|uniprotkb:E9R297|uniprotkb:Q81WY3|uniprotkb:A0A1J9VPA6|uniprotkb:A0A0J1HTG5	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	psi-mi:a0a4y1wb04_bacan(display_long)|uniprotkb:GBAA_5468(locus name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832641|imex:IM-13779-3672	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010652(Protein of unknown function DUF1232)|interpro:IPR016983(Uncharacterised conserved protein UCP031804)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|refseq:WP_000435503.1"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:BJqIUz/7uOTqNy4f7DQKBxNl8Pw1392	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	intact-crc:20847DF750615279|rigid:aszm3is36vzSo1pTwQmmtFRVf6w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00165	uniprotkb:A0A6L8PU14	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	intact:EBI-2817545|uniprotkb:Q6KXS2|uniprotkb:Q6I411|uniprotkb:E9R0X4|uniprotkb:E9R0X5|uniprotkb:Q81Z69|uniprotkb:A0A0F7RNN8	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:a0a6l8pu14_bacan(display_long)|uniprotkb:GBAA_0403(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832669|imex:IM-13779-3677	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	interpro:IPR025647|refseq:WP_000492843.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rogid:dljX03A4clbrBCvL6AMsyZDP5JQ1392	intact-crc:2A5ED194B25D2BF0|rigid:8vnd27fWsawMJvPiAKD3icXGOa4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00165	uniprotkb:Q81KV7	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	intact:EBI-2819109|uniprotkb:Q6KLK9|uniprotkb:Q6HSB3	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:assy_bacan(display_long)|uniprotkb:argG(gene name)|psi-mi:argG(display_short)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:BA_4880(locus name)|uniprotkb:GBAA_4880(locus name)|uniprotkb:BAS4528(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832655|imex:IM-13779-3673	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|go:""GO:0000050""(urea cycle)|go:""GO:0000053""(argininosuccinate metabolic process)|go:""GO:0004055""(argininosuccinate synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|refseq:WP_000412328.1|refseq:NP_847081.1|refseq:YP_030775.1|interpro:IPR048267|interpro:IPR048268"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rogid:5ecBR1qj/ajGIxCdyzTMfvl1+tA1392	intact-crc:D9DCB098F5B7A47E|rigid:K1y+A9rJVdV1Xy0WcK3GJuCLE3o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81SR4	uniprotkb:O00165	intact:EBI-2815297|uniprotkb:Q6KUV0|uniprotkb:Q6I0Z6	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	psi-mi:y1582_bacan(display_long)|uniprotkb:BA_1582(locus name)|uniprotkb:GBAA_1582(locus name)|uniprotkb:BAS1466(locus name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832662|imex:IM-13779-3676	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010697(Protein of unknown function DUF1273)|refseq:WP_000862924.1|refseq:NP_844031.1|refseq:YP_027735.1	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:kRkzWueeQf18LltGErdS4DVGq+M1392	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	intact-crc:94242898F553D120|rigid:3UHTpsmnOD153B5ViJxfXzfwSRs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00165	uniprotkb:A0A6L7HHZ0	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	intact:EBI-2815990|uniprotkb:Q6HWE4|uniprotkb:Q6KQJ2|uniprotkb:E9R1E8|uniprotkb:E9R1E9|uniprotkb:Q81N85|uniprotkb:A0A0F7R9Q0	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:a0a6l7hhz0_bacan(display_long)|uniprotkb:GBAA_3330(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832709|imex:IM-13779-3680	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"interpro:IPR014395(Penicillin/cephalosporin acylase)|interpro:IPR023343|interpro:IPR002692(Peptidase S45, penicillin amidase)|interpro:IPR029055|go:""GO:0016020""(membrane)|go:""GO:0016811""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"")|go:""GO:0017000""(antibiotic biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_000454347.1|interpro:IPR043146|interpro:IPR043147"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rogid:GA7t0x65oVV/xsMxmTMwbYISEAA1392	intact-crc:9FAA9F5DD6E5AB04|rigid:u5hRmMc5MTw7D2/bdEL3nnSg8Xg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00165	uniprotkb:A0A6L7HH25	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	intact:EBI-2832700|uniprotkb:Q6KQT5|uniprotkb:Q6HWP2|uniprotkb:E9QVL9|uniprotkb:E9QVM0|uniprotkb:Q81NH9|uniprotkb:A0A0F7RA18	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:a0a6l7hh25_bacan(display_long)|uniprotkb:GBAA_3214(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832697|imex:IM-13779-3679	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|refseq:WP_000428450.1|interpro:IPR050491	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rogid:i1yyjENPXN/+gDJ5NrlYd/Hac6A1392	intact-crc:1FB154AE36870E43|rigid:GctbWU8K9SApTdwP0Y3lc+bXqWg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00165	uniprotkb:A0A6L7H2Q9	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	intact:EBI-2810400|uniprotkb:Q6KTQ9|uniprotkb:Q6HZS4|uniprotkb:E9RAZ3|uniprotkb:E9RAZ4|uniprotkb:Q81RJ7|uniprotkb:A0A0F7RD30	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:a0a6l7h2q9_bacan(display_long)|uniprotkb:GBAA_2047(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832690|imex:IM-13779-3681	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:WP_000216920.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rogid:H+yb15aOHMi9sIfuMqerdtx927Y1392	intact-crc:DDDF341D43176AD5|rigid:3QU/7YeV32qL545Y3D8m/sGRCyc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0J1KLZ7	uniprotkb:O00165	intact:EBI-2822063|uniprotkb:Q6KJ42|uniprotkb:E9R5M8|uniprotkb:Q81N06	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	psi-mi:a0a0j1klz7_bacan(display_long)|uniprotkb:GBAA_3413(locus name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832716|imex:IM-13779-3682	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000945244.1	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:t8CroOX3cma9aG7JpLpi9U1ql8U1392	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	intact-crc:CB85BE6D8C9D8AC6|rigid:l8IUE9dAdUuEck8wBY52pub6T20	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00165	uniprotkb:A0A6L7H5N1	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832683|imex:IM-13779-3678	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:D9387F74B1FC6A80|rigid:lBhVlzlLXJfmTrrQd3BOoWBq5DY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q75N03	uniprotkb:A0A6L7HDD5	intact:EBI-2832762|uniprotkb:Q9H5S6|uniprotkb:Q8TAJ4|uniprotkb:B7ZM03|ensembl:ENSP00000401277.2|intact:EBI-28973894	intact:EBI-2813515|uniprotkb:Q6KL28|uniprotkb:Q6HRS0|uniprotkb:E9R8R5|uniprotkb:E9R8R6|uniprotkb:A0A2P0HKM5|uniprotkb:Q81KB5	psi-mi:hakai_human(display_long)|uniprotkb:CBLL1(gene name)|psi-mi:CBLL1(display_short)|uniprotkb:HAKAI(gene name synonym)|uniprotkb:RNF188(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma-transforming sequence-like protein 1(gene name synonym)|uniprotkb:RING finger protein 188(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Hakai(gene name synonym)	psi-mi:a0a6l7hdd5_bacan(display_long)|uniprotkb:GBAA_5086(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832759|imex:IM-13779-3686	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001271220.1|refseq:NP_079090.2|ensembl:ENSG00000105879.13(gene)|ensembl:ENST00000440859.8(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0007162""(negative regulation of cell adhesion)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016607""(nuclear speck)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0036396""(RNA N6-methyladenosine methyltransferase complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0045807""(positive regulation of endocytosis)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0098609""(cell-cell adhesion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR040380|interpro:IPR040383|interpro:IPR041042|mint:Q75N03|reactome:R-HSA-8876493|panther:PTHR13480(orthology-group)"	"interpro:IPR010499(Bacterial transcription activator, effector binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018062|interpro:IPR018060|interpro:IPR011256(Regulatory factor, effector, bacterial)|interpro:IPR020449|interpro:IPR050959|interpro:IPR029442|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0043565""(sequence-specific DNA binding)|refseq:WP_000377705.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DqJluJuMnJy0AHXYfPKwS5s7SOM9606	rogid:hyJD8M1O1yrezwfoHqii1Vf8lq41392	intact-crc:2A5119287871637B|rigid:30PFM28MtsgkgfOccoO4+uFk2FM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7GYY0	uniprotkb:O14929	intact:EBI-2832738|uniprotkb:Q6HT87|uniprotkb:Q6KMH8|uniprotkb:E9QWS4|uniprotkb:E9QWS5|uniprotkb:Q81LT3|uniprotkb:A0A1J9WM55	intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108.4	psi-mi:a0a6l7gyy0_bacan(display_long)|uniprotkb:GBAA_4528(locus name)	psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832735|imex:IM-13779-3683	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|refseq:WP_000946454.1|go:""GO:0016020""(membrane)|interpro:IPR052722"	"refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708.13(gene)|ensembl:ENST00000264108.5(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006475""(internal protein amino acid acetylation)|go:""GO:0010485""(histone H4 acetyltransferase activity)|go:""GO:0016363""(nuclear matrix)|go:""GO:0031509""(subtelomeric heterochromatin formation)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042393""(histone binding)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0051276""(chromosome organization)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|interpro:IPR048776|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847|panther:PTHR12046(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:RlM2bsAcJdXqyvRrDOmshzrdcJU1392	rogid:BS/Wvu5hWHAweZ9aApSrQfOGXdA9606	intact-crc:7392654034FC0CF1|rigid:/RISzCzSYQ0zbHWEaGcPPyeYvCo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AND8	uniprotkb:O00165	intact:EBI-2832726|uniprotkb:Q6KN87|uniprotkb:Q6HU06|uniprotkb:E9R8B7|uniprotkb:E9R8B8|uniprotkb:Q81MK7|uniprotkb:A0A0J1KEN4|uniprotkb:A0A2A8KT75	intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002.7|ensembl:ENSP00000512979.1	psi-mi:a0a6h3and8_bacan(display_long)|uniprotkb:Acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:GBAA_4240(locus name)	psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832723|imex:IM-13779-3685	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020617|interpro:IPR020616|rcsb pdb:3SS6|refseq:WP_000552083.1|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)"	"efo:""Orphanet:99749""|ensembl:ENSG00000143575.16(gene)|ensembl:ENST00000328703.12(transcript)|ensembl:ENST00000696932.1(transcript)|go:""GO:0000932""(P-body)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005938""(cell cortex)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016529""(sarcoplasmic reticulum)|go:""GO:0019966""(interleukin-1 binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030833""(regulation of actin filament polymerization)|go:""GO:0030854""(positive regulation of granulocyte differentiation)|go:""GO:0031965""(nuclear membrane)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0038158""(granulocyte colony-stimulating factor signaling pathway)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071345""(cellular response to cytokine stimulus)|go:""GO:0110053""(regulation of actin filament organization)|go:""GO:1903146""(regulation of autophagy of mitochondrion)|go:""GO:1903214""(regulation of protein targeting to mitochondrion)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165|refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|panther:PTHR14938(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:SKXsgX1X+Ubf0NoamZVXhcTYGWs1392	rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606	intact-crc:274C34BE848D438A|rigid:d6F0XoixUKnIc4MVyz3KR/VYDk0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PXJ9	uniprotkb:Q13442	intact:EBI-2832747|uniprotkb:Q6KMA5|uniprotkb:Q6HT16|uniprotkb:E9R2F6|uniprotkb:E9R2F7|uniprotkb:Q81LL0|uniprotkb:A0A0F7R810	intact:EBI-1390763|uniprotkb:Q92906|uniprotkb:D6W5S5|ensembl:ENSP00000222968.4	psi-mi:a0a6l8pxj9_bacan(display_long)|uniprotkb:GBAA_4606(locus name)	psi-mi:hap28_human(display_long)|uniprotkb:PDGF-associated protein(gene name synonym)|uniprotkb:PDGFA-associated protein 1(gene name synonym)|uniprotkb:PDAP1(gene name)|psi-mi:PDAP1(display_short)|uniprotkb:HASPP28(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832752|imex:IM-13779-3684	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|refseq:WP_000695125.1|go:""GO:0005886""(plasma membrane)|go:""GO:0008658""(penicillin binding)|go:""GO:0071555""(cell wall organization)|go:""GO:0071972""(peptidoglycan L,D-transpeptidase activity)|interpro:IPR036138|interpro:IPR050515|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)"	"refseq:NP_055706.1|panther:PTHR22055(orthology-group)|ensembl:ENSG00000106244.13(gene)|ensembl:ENST00000350498.8(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|interpro:IPR019380|interpro:IPR039876|mint:Q13442|reactome:R-HSA-6798695"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FbAs8bbn2yiJ7JxIOpH5LHEK3OQ1392	rogid:8oY/0PM5kBr34vOdRXuGjIVFMgU9606	intact-crc:A2F33AD1460C9A93|rigid:1YTVakLSP7uOONvYtXy9Q0Uu16Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H165	uniprotkb:O14929	intact:EBI-2811597|uniprotkb:Q6KPI1|uniprotkb:Q6HVB3|uniprotkb:E9QV35|uniprotkb:E9QV36|uniprotkb:A0A2P0HHN5|uniprotkb:Q81Y15	intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108.4	psi-mi:a0a6l7h165_bacan(display_long)|uniprotkb:GBAA_3744(locus name)|uniprotkb:tkt2(gene name)|psi-mi:tkt2(display_short)	psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832772|imex:IM-13779-3691	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033247|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|rcsb pdb:3M49|interpro:IPR029061|go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|refseq:WP_000019755.1|rcsb pdb:3HYL|interpro:IPR049557"	"refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708.13(gene)|ensembl:ENST00000264108.5(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000785""(chromatin)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006475""(internal protein amino acid acetylation)|go:""GO:0010485""(histone H4 acetyltransferase activity)|go:""GO:0016363""(nuclear matrix)|go:""GO:0031509""(subtelomeric heterochromatin formation)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042393""(histone binding)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0051276""(chromosome organization)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|interpro:IPR048776|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847|panther:PTHR12046(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:/3w4Fmuo2N06ZcrbsjphHSbI8do1392	rogid:BS/Wvu5hWHAweZ9aApSrQfOGXdA9606	intact-crc:037D7C6FEAE25DD8|rigid:i9HVIue1gtpdoMja4TKClMMxcOE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7REH3	uniprotkb:P84243	intact:EBI-2811064|uniprotkb:Q6KPV8|uniprotkb:E9R093|uniprotkb:Q81YE8	intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810.3|ensembl:ENSP00000355778.1|ensembl:ENSP00000355780.3|ensembl:ENSP00000355781.1|ensembl:ENSP00000465813.1|ensembl:ENSP00000466020.1|ensembl:ENSP00000468714.1|ensembl:ENSP00000499275.1|ensembl:ENSP00000499385.1|ensembl:ENSP00000499800.1	psi-mi:a0a0f7reh3_bacan(display_long)|uniprotkb:GBAA_3601(locus name)	psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832786|imex:IM-13779-3690	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001116379.1|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR047589	"refseq:NP_002098.1|refseq:NP_005315.1|dip:DIP-40046N|ensembl:ENSG00000132475.10(gene)|ensembl:ENSG00000163041.13(gene)|ensembl:ENST00000254810.8(transcript)|ensembl:ENST00000366813.1(transcript)|ensembl:ENST00000366815.10(transcript)|ensembl:ENST00000366816.5(transcript)|ensembl:ENST00000586607.5(transcript)|ensembl:ENST00000587560.5(transcript)|ensembl:ENST00000589599.5(transcript)|ensembl:ENST00000655399.1(transcript)|ensembl:ENST00000661429.1(transcript)|ensembl:ENST00000666609.1(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000786""(nucleosome)|go:""GO:0000939""(inner kinetochore)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0001556""(oocyte maturation)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001740""(Barr body)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006997""(nucleus organization)|go:""GO:0007286""(spermatid development)|go:""GO:0007338""(single fertilization)|go:""GO:0007566""(embryo implantation)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008584""(male gonad development)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030527""(structural constituent of chromatin)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0031508""(pericentric heterochromatin formation)|go:""GO:0031509""(subtelomeric heterochromatin formation)|go:""GO:0032200""(telomere organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090230""(regulation of centromere complex assembly)|go:""GO:1902340""(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|rcsb pdb:3QL9|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:3WTP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4GNG|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4U7T|rcsb pdb:4W5A|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7CWH|rcsb pdb:7OKP|rcsb pdb:7V1L|rcsb pdb:7V1M|rcsb pdb:7VCQ|rcsb pdb:7W5M|rcsb pdb:7WBV|rcsb pdb:7WBW|rcsb pdb:7WBX|rcsb pdb:7XSE|rcsb pdb:7XSX|rcsb pdb:7XSZ|rcsb pdb:7XT7|rcsb pdb:7XTD|rcsb pdb:7XTI|rcsb pdb:8JH2|rcsb pdb:8JH3|rcsb pdb:8JH4|rcsb pdb:8KB5|rcsb pdb:9B3P|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-68616|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-9821002|reactome:R-HSA-9821993|reactome:R-HSA-983231|reactome:R-HSA-9841922|reactome:R-HSA-9843940|reactome:R-HSA-9843970|reactome:R-HSA-9845323|panther:PTHR11426(orthology-group)|ensembl:ENSP00000254810.3|ensembl:ENSP00000355778.1|ensembl:ENSP00000355780.3|ensembl:ENSP00000355781.1|ensembl:ENSP00000466020.1|ensembl:ENSP00000468714.1|ensembl:ENSP00000465813.1|ensembl:ENSP00000499800.1|ensembl:ENSP00000499385.1|ensembl:ENSP00000499275.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:kRV2TrznOHMKW2jOg5FKoFx9L+41392	rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606	intact-crc:C47E7F30C624929F|rigid:e3h9hO8VfdvOdn/Dv/VxO0ons6U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P78347	uniprotkb:A0A6L7H165	intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070.1	intact:EBI-2811597|uniprotkb:Q6KPI1|uniprotkb:Q6HVB3|uniprotkb:E9QV35|uniprotkb:E9QV36|uniprotkb:A0A2P0HHN5|uniprotkb:Q81Y15	psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym)	psi-mi:a0a6l7h165_bacan(display_long)|uniprotkb:GBAA_3744(locus name)|uniprotkb:tkt2(gene name)|psi-mi:tkt2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832800|imex:IM-13779-3689	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:904""|ensembl:ENSG00000263001.8(gene)|ensembl:ENST00000573035.6(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|interpro:IPR036647|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|refseq:NP_001157108.1|refseq:NP_001267729.1|refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|dip:DIP-24252N|panther:PTHR46304(orthology-group)"	"interpro:IPR033247|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|rcsb pdb:3M49|interpro:IPR029061|go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|refseq:WP_000019755.1|rcsb pdb:3HYL|interpro:IPR049557"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606	rogid:/3w4Fmuo2N06ZcrbsjphHSbI8do1392	intact-crc:D9F9BEDC7D8C81BF|rigid:gbZGR/AF8VjOG5JyJB4rHb5JUlg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PC29	uniprotkb:P84243	intact:EBI-2810801|uniprotkb:Q6KRM4|uniprotkb:Q6HXJ8|uniprotkb:E9QRE3|uniprotkb:E9QRE4|uniprotkb:A0A2P0HF49|uniprotkb:Q81PD4	intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810.3|ensembl:ENSP00000355778.1|ensembl:ENSP00000355780.3|ensembl:ENSP00000355781.1|ensembl:ENSP00000465813.1|ensembl:ENSP00000466020.1|ensembl:ENSP00000468714.1|ensembl:ENSP00000499275.1|ensembl:ENSP00000499385.1|ensembl:ENSP00000499800.1	psi-mi:a0a6l8pc29_bacan(display_long)|uniprotkb:GBAA_2876(locus name)	psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832779|imex:IM-13779-3687	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001062740.1	"refseq:NP_002098.1|refseq:NP_005315.1|dip:DIP-40046N|ensembl:ENSG00000132475.10(gene)|ensembl:ENSG00000163041.13(gene)|ensembl:ENST00000254810.8(transcript)|ensembl:ENST00000366813.1(transcript)|ensembl:ENST00000366815.10(transcript)|ensembl:ENST00000366816.5(transcript)|ensembl:ENST00000586607.5(transcript)|ensembl:ENST00000587560.5(transcript)|ensembl:ENST00000589599.5(transcript)|ensembl:ENST00000655399.1(transcript)|ensembl:ENST00000661429.1(transcript)|ensembl:ENST00000666609.1(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000786""(nucleosome)|go:""GO:0000939""(inner kinetochore)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000979""(RNA polymerase II core promoter sequence-specific DNA binding)|go:""GO:0001556""(oocyte maturation)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0001740""(Barr body)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006334""(nucleosome assembly)|go:""GO:0006997""(nucleus organization)|go:""GO:0007286""(spermatid development)|go:""GO:0007338""(single fertilization)|go:""GO:0007566""(embryo implantation)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008584""(male gonad development)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030527""(structural constituent of chromatin)|go:""GO:0031492""(nucleosomal DNA binding)|go:""GO:0031508""(pericentric heterochromatin formation)|go:""GO:0031509""(subtelomeric heterochromatin formation)|go:""GO:0032200""(telomere organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090230""(regulation of centromere complex assembly)|go:""GO:1902340""(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|rcsb pdb:3QL9|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:3WTP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4GNG|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4U7T|rcsb pdb:4W5A|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7CWH|rcsb pdb:7OKP|rcsb pdb:7V1L|rcsb pdb:7V1M|rcsb pdb:7VCQ|rcsb pdb:7W5M|rcsb pdb:7WBV|rcsb pdb:7WBW|rcsb pdb:7WBX|rcsb pdb:7XSE|rcsb pdb:7XSX|rcsb pdb:7XSZ|rcsb pdb:7XT7|rcsb pdb:7XTD|rcsb pdb:7XTI|rcsb pdb:8JH2|rcsb pdb:8JH3|rcsb pdb:8JH4|rcsb pdb:8KB5|rcsb pdb:9B3P|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-68616|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-9821002|reactome:R-HSA-9821993|reactome:R-HSA-983231|reactome:R-HSA-9841922|reactome:R-HSA-9843940|reactome:R-HSA-9843970|reactome:R-HSA-9845323|panther:PTHR11426(orthology-group)|ensembl:ENSP00000254810.3|ensembl:ENSP00000355778.1|ensembl:ENSP00000355780.3|ensembl:ENSP00000355781.1|ensembl:ENSP00000466020.1|ensembl:ENSP00000468714.1|ensembl:ENSP00000465813.1|ensembl:ENSP00000499800.1|ensembl:ENSP00000499385.1|ensembl:ENSP00000499275.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:4BbTj8554Gwm4rVypGL1Pva9DGE1392	rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606	intact-crc:EE7CE154226F8659|rigid:qwOohpX4e6bd4xwDg5Avpn+h0jg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11169	uniprotkb:A0A6L8PKS7	intact:EBI-725116|uniprotkb:Q6I9U2|uniprotkb:Q9UG15|uniprotkb:D3DUU6|uniprotkb:B2R606|ensembl:ENSP00000075120.7|ensembl:ENSP00000516774.1	intact:EBI-2809705|uniprotkb:Q6HR58|uniprotkb:Q6KKH5|uniprotkb:E9QWF2|uniprotkb:E9QWF3|uniprotkb:A0A2P0HL14|uniprotkb:Q81XC3	psi-mi:gtr3_human(display_long)|uniprotkb:Glucose transporter type 3, brain(gene name synonym)|uniprotkb:SLC2A3(gene name)|psi-mi:SLC2A3(display_short)|uniprotkb:GLUT3(gene name synonym)	psi-mi:a0a6l8pks7_bacan(display_long)|uniprotkb:GBAA_5317(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832793|imex:IM-13779-3688	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:399""|ensembl:ENSG00000059804.18(gene)|ensembl:ENST00000075120.12(transcript)|ensembl:ENST00000707174.1(transcript)|go:""GO:0005354""(galactose transmembrane transporter activity)|go:""GO:0005536""(D-glucose binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0015757""(galactose transmembrane transport)|go:""GO:0016020""(membrane)|go:""GO:0016235""(aggresome)|go:""GO:0019852""(L-ascorbic acid metabolic process)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0033300""(dehydroascorbic acid transmembrane transporter activity)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042995""(cell projection)|go:""GO:0043204""(perikaryon)|go:""GO:0046323""(D-glucose import)|go:""GO:0055056""(D-glucose transmembrane transporter activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0070837""(dehydroascorbic acid transport)|go:""GO:0098708""(D-glucose import across plasma membrane)|go:""GO:0101003""(ficolin-1-rich granule membrane)|go:""GO:0150104""(transport across blood-brain barrier)|go:""GO:1904659""(D-glucose transmembrane transport)|interpro:IPR002945(Glucose transporter GLUT3, type 3)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|interpro:IPR045263|mint:P11169|rcsb pdb:4ZW9|rcsb pdb:4ZWB|rcsb pdb:4ZWC|rcsb pdb:5C65|rcsb pdb:7CRZ|rcsb pdb:7SPS|rcsb pdb:7SPT|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-6798695|reactome:R-HSA-9022699|refseq:NP_008862.1|panther:PTHR23503(orthology-group)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR051310|interpro:IPR025278|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|refseq:WP_000455036.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4lvD/2COzfHcIKxN1l9FsXOJWnk9606	rogid:LEAQuRzrOsJwYgZq7QXDmoKrfqM1392	intact-crc:EA56DA519E4D35EC|rigid:lo6+1fxUdeh5wV+xHQlkLbeMpUo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09211	uniprotkb:A0A6L8PX73	intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607.3|uniprotkb:Q5TZY3	intact:EBI-2814460|uniprotkb:Q6HTD2|uniprotkb:Q6KMM4|uniprotkb:E9R6D4|uniprotkb:E9R6D5|uniprotkb:Q81LY0|uniprotkb:A0A0J1HYA4	psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym)	psi-mi:a0a6l8px73_bacan(display_long)|uniprotkb:GBAA_4479(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832814|imex:IM-13779-3695	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000843.1|ensembl:ENSG00000084207.18(gene)|ensembl:ENST00000398606.10(transcript)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0002674""(negative regulation of acute inflammatory response)|go:""GO:0004364""(glutathione transferase activity)|go:""GO:0004602""(glutathione peroxidase activity)|go:""GO:0005504""(fatty acid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006693""(prostaglandin metabolic process)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0007417""(central nervous system development)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0009890""(negative regulation of biosynthetic process)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0019207""(kinase regulator activity)|go:""GO:0031982""(vesicle)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0032873""(negative regulation of stress-activated MAPK cascade)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0035730""(S-nitrosoglutathione binding)|go:""GO:0035731""(dinitrosyl-iron complex binding)|go:""GO:0035732""(nitric oxide storage)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043508""(negative regulation of JUN kinase activity)|go:""GO:0043651""(linoleic acid metabolic process)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0051122""(hepoxilin biosynthetic process)|go:""GO:0051771""(obsolete negative regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0070026""(nitric oxide binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070664""(negative regulation of leukocyte proliferation)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071638""(negative regulation of monocyte chemotactic protein-1 production)|go:""GO:0097057""(TRAF2-GSTP1 complex)|go:""GO:1901687""(glutathione derivative biosynthetic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|interpro:IPR050213|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7BIA|rcsb pdb:7GSS|rcsb pdb:7XBA|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9753281|panther:PTHR11571(orthology-group)"	"interpro:IPR003171(Methylenetetrahydrofolate reductase)|interpro:IPR003726(Homocysteine S-methyltransferase)|interpro:IPR050554|interpro:IPR029041|go:""GO:0004489""(""methylenetetrahydrofolate reductase (NAD(P)H) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0008705""(methionine synthase activity)|go:""GO:0032259""(methylation)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|refseq:WP_000770331.1|interpro:IPR036589"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606	rogid:kwYps3uM+vfuLmFjfNZe8XCRW/U1392	intact-crc:984DA364911E87B6|rigid:8gRd3C1xoJpQgXDk3GEx3XI1XsM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09488	uniprotkb:A0A6H3AKP3	intact:EBI-350409|uniprotkb:Q5GHG0|uniprotkb:Q6FH88|uniprotkb:Q9UC96|uniprotkb:Q8TC98|ensembl:ENSP00000311469.5	intact:EBI-2813310|uniprotkb:Q6KM94|uniprotkb:Q6HT04|uniprotkb:E9QTN5|uniprotkb:E9QTN6|uniprotkb:Q81LJ8|uniprotkb:A0A1V4BJH0	psi-mi:gstm1_human(display_long)|uniprotkb:GSTM1(gene name)|psi-mi:GSTM1(display_short)|uniprotkb:GST1(gene name synonym)|uniprotkb:GSTM1-1(gene name synonym)|uniprotkb:GST class-mu 1(gene name synonym)|uniprotkb:GSTM1a-1a(gene name synonym)|uniprotkb:GSTM1b-1b(gene name synonym)|uniprotkb:GST HB subunit 4(gene name synonym)|uniprotkb:GTH4(gene name synonym)	psi-mi:a0a6h3akp3_bacan(display_long)|uniprotkb:GBAA_4618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832821|imex:IM-13779-3693	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000552.2|refseq:NP_666533.1|ensembl:ENSG00000134184.13(gene)|ensembl:ENST00000309851.10(transcript)|go:""GO:0004364""(glutathione transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006693""(prostaglandin metabolic process)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0018916""(nitrobenzene metabolic process)|go:""GO:0019899""(enzyme binding)|go:""GO:0042178""(xenobiotic catabolic process)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043295""(glutathione binding)|go:""GO:0045171""(intercellular bridge)|go:""GO:0051122""(hepoxilin biosynthetic process)|go:""GO:0070458""(cellular detoxification of nitrogen compound)|go:""GO:1901687""(glutathione derivative biosynthetic process)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|interpro:IPR050213|rcsb pdb:1GTU|rcsb pdb:1XW6|rcsb pdb:1XWK|rcsb pdb:1YJ6|rcsb pdb:2F3M|rcsb pdb:7BEU|reactome:R-HSA-156590|reactome:R-HSA-9748787|reactome:R-HSA-9753281|panther:PTHR11571(orthology-group)"	"refseq:WP_000793108.1|interpro:IPR002549(Protein of unknown function UPF0118)|go:""GO:0016020""(membrane)|go:""GO:0055085""(transmembrane transport)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/cuHGWU57I+yHHaJM99UyWcAy4c9606	rogid:EuoKynuHXFv/xrmnc1nvaUXmtMM1392	intact-crc:8E553F5F04D4A5C6|rigid:3Kj3Z1z1U4rfYHvPMCjxXa09ENo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08263	uniprotkb:Q6HQX5	intact:EBI-2832828|uniprotkb:Q14750|uniprotkb:Q5GHF8|uniprotkb:Q5SZC1|ensembl:ENSP00000335620.5	intact:EBI-2820871|uniprotkb:Q81X38|uniprotkb:Q6KK93	psi-mi:gsta1_human(display_long)|uniprotkb:GSTA1(gene name)|psi-mi:GSTA1(display_short)|uniprotkb:GST HA subunit 1(gene name synonym)|uniprotkb:GST class-alpha member 1(gene name synonym)|uniprotkb:GST-epsilon(gene name synonym)|uniprotkb:GSTA1-1(gene name synonym)|uniprotkb:GTH1(gene name synonym)|uniprotkb:13-hydroperoxyoctadecadienoate peroxidase(gene name synonym)|uniprotkb:Androst-5-ene-3,17-dione isomerase(gene name synonym)	psi-mi:y5405_bacan(display_long)|uniprotkb:BA_5405(locus name)|uniprotkb:GBAA_5405(locus name)|uniprotkb:BAS5024(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832833|imex:IM-13779-3694	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_665683.1|ensembl:ENSG00000243955.6(gene)|ensembl:ENST00000334575.6(transcript)|go:""GO:0004364""(glutathione transferase activity)|go:""GO:0004602""(glutathione peroxidase activity)|go:""GO:0004769""(steroid Delta-isomerase activity)|go:""GO:0005504""(fatty acid binding)|go:""GO:0005829""(cytosol)|go:""GO:0006693""(prostaglandin metabolic process)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0043651""(linoleic acid metabolic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1901687""(glutathione derivative biosynthetic process)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|interpro:IPR050213|rcsb pdb:1GSD|rcsb pdb:1GSE|rcsb pdb:1GSF|rcsb pdb:1GUH|rcsb pdb:1K3L|rcsb pdb:1K3O|rcsb pdb:1K3Y|rcsb pdb:1LBK|rcsb pdb:1PKW|rcsb pdb:1PKZ|rcsb pdb:1PL1|rcsb pdb:1PL2|rcsb pdb:1USB|rcsb pdb:1XWG|rcsb pdb:1YDK|rcsb pdb:2R3X|rcsb pdb:2R6K|rcsb pdb:3I69|rcsb pdb:3I6A|rcsb pdb:3IK9|rcsb pdb:3KTL|rcsb pdb:3L0H|rcsb pdb:3Q74|rcsb pdb:3U6V|rcsb pdb:3ZFB|rcsb pdb:3ZFL|rcsb pdb:4HJ2|rcsb pdb:5JCU|rcsb pdb:5LCZ|rcsb pdb:5LD0|rcsb pdb:6ATO|rcsb pdb:6ATP|rcsb pdb:6ATQ|rcsb pdb:6ATR|rcsb pdb:6YAW|rcsb pdb:7BIB|rcsb pdb:7BIC|rcsb pdb:8BHC|rcsb pdb:8BHE|reactome:R-HSA-156590|reactome:R-HSA-189483|reactome:R-HSA-9748787|reactome:R-HSA-9818027|panther:PTHR11571(orthology-group)"	"interpro:IPR018383|refseq:WP_000438452.1|go:""GO:0005886""(plasma membrane)|refseq:NP_847578.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:64iIx7wflyxOfm279mt+1SUsX8U9606	rogid:+70rorqsLLtuubrUKzvzgPK76Yk1392	intact-crc:1CB614D392921B0D|rigid:rku9ud6cm71x3lTQQLKm16RBGeM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48506	uniprotkb:A0A6L7HC63	intact:EBI-2832840|uniprotkb:Q14399|ensembl:ENSP00000497574.1	intact:EBI-2811370|uniprotkb:Q6KTZ3|uniprotkb:Q6I014|uniprotkb:E9QYA2|uniprotkb:E9QYA3|uniprotkb:Q81RT7|uniprotkb:A0A0F7RJ72	psi-mi:gsh1_human(display_long)|uniprotkb:GCLC(gene name)|psi-mi:GCLC(display_short)|uniprotkb:GLCL(gene name synonym)|uniprotkb:GLCLC(gene name synonym)|uniprotkb:GCS heavy chain(gene name synonym)|uniprotkb:Gamma-ECS(gene name synonym)|uniprotkb:Gamma-glutamylcysteine synthetase(gene name synonym)	psi-mi:a0a6l7hc63_bacan(display_long)|uniprotkb:GBAA_1950(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832845|imex:IM-13779-3696	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:33574""|efo:""Orphanet:586""|ensembl:ENSG00000001084.13(gene)|ensembl:ENST00000650454.1(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004357""(glutamate-cysteine ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006534""(cysteine metabolic process)|go:""GO:0006536""(glutamate metabolic process)|go:""GO:0006750""(glutathione biosynthetic process)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007584""(response to nutrient)|go:""GO:0009408""(response to heat)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009725""(response to hormone)|go:""GO:0014823""(response to activity)|go:""GO:0016595""(glutamate binding)|go:""GO:0017109""(glutamate-cysteine ligase complex)|go:""GO:0019852""(L-ascorbic acid metabolic process)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0035729""(cellular response to hepatocyte growth factor stimulus)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043531""(ADP binding)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0044752""(response to human chorionic gonadotropin)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046685""(response to arsenic-containing substance)|go:""GO:0046686""(response to cadmium ion)|go:""GO:0051409""(response to nitrosative stress)|go:""GO:0051900""(regulation of mitochondrial depolarization)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071372""(cellular response to follicle-stimulating hormone stimulus)|go:""GO:0097069""(cellular response to thyroxine stimulus)|go:""GO:0097746""(blood vessel diameter maintenance)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:2000490""(negative regulation of hepatic stellate cell activation)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR004308(Glutamate-cysteine ligase catalytic subunit)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-174403|reactome:R-HSA-5578999|reactome:R-HSA-9818027|refseq:NP_001184044.1|refseq:NP_001489.1|panther:PTHR11164(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR018044|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0071555""(cell wall organization)|refseq:WP_000825873.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EcbMKzIB2YBbUBswkGfUFZUPC9s9606	rogid:C+GkPog4qlTLKuFTOFPtKPvk7yQ1392	intact-crc:BEECBD3363FC7FAD|rigid:X4q65C+eb2uOW92MP+xNQMm+Q9A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P09211	uniprotkb:A0A6L7H9A7	intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607.3|uniprotkb:Q5TZY3	intact:EBI-2816086|uniprotkb:Q6KKA3|uniprotkb:Q6HQY4|uniprotkb:E9QWA3|uniprotkb:E9QWA4|uniprotkb:Q81X48|uniprotkb:A0A1J9WVL8	psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym)	psi-mi:a0a6l7h9a7_bacan(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:GBAA_5395(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832807|imex:IM-13779-3692	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000843.1|ensembl:ENSG00000084207.18(gene)|ensembl:ENST00000398606.10(transcript)|go:""GO:0000302""(response to reactive oxygen species)|go:""GO:0002674""(negative regulation of acute inflammatory response)|go:""GO:0004364""(glutathione transferase activity)|go:""GO:0004602""(glutathione peroxidase activity)|go:""GO:0005504""(fatty acid binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006693""(prostaglandin metabolic process)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0007417""(central nervous system development)|go:""GO:0008432""(JUN kinase binding)|go:""GO:0009890""(negative regulation of biosynthetic process)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0019207""(kinase regulator activity)|go:""GO:0031982""(vesicle)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032872""(regulation of stress-activated MAPK cascade)|go:""GO:0032873""(negative regulation of stress-activated MAPK cascade)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035726""(common myeloid progenitor cell proliferation)|go:""GO:0035730""(S-nitrosoglutathione binding)|go:""GO:0035731""(dinitrosyl-iron complex binding)|go:""GO:0035732""(nitric oxide storage)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043407""(negative regulation of MAP kinase activity)|go:""GO:0043409""(negative regulation of MAPK cascade)|go:""GO:0043508""(negative regulation of JUN kinase activity)|go:""GO:0043651""(linoleic acid metabolic process)|go:""GO:0048147""(negative regulation of fibroblast proliferation)|go:""GO:0051122""(hepoxilin biosynthetic process)|go:""GO:0051771""(obsolete negative regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0070026""(nitric oxide binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070664""(negative regulation of leukocyte proliferation)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071638""(negative regulation of monocyte chemotactic protein-1 production)|go:""GO:0097057""(TRAF2-GSTP1 complex)|go:""GO:1901687""(glutathione derivative biosynthetic process)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|interpro:IPR050213|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7BIA|rcsb pdb:7GSS|rcsb pdb:7XBA|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9753281|panther:PTHR11571(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000045565.1|interpro:IPR041102|interpro:IPR041552|interpro:IPR013815(ATP-grasp fold, subdomain 1)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606	rogid:8J+yjOUWiDCOsqLZUtYwrwWzv241392	intact-crc:4CD6EEA90ED33B79|rigid:V5PcCcQNgVIaE1cCBlBho8AEaq0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZM5	uniprotkb:A0A6L7H167	intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802.4	intact:EBI-2816818|uniprotkb:Q6HUX7|uniprotkb:Q6KP53|uniprotkb:E9QR95|uniprotkb:E9QR96|uniprotkb:Q81WS3	psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym)	psi-mi:a0a6l7h167_bacan(display_long)|uniprotkb:GBAA_3895(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832878|imex:IM-13779-3698	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056525.2|ensembl:ENSG00000105373.19(gene)|ensembl:ENST00000246802.10(transcript)|go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002039""(p53 binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006364""(rRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0008097""(5S rRNA binding)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0039535""(regulation of RIG-I signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050821""(protein stabilization)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1901797""(negative regulation of signal transduction by p53 class mediator)|go:""GO:1901837""(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1902570""(protein localization to nucleolus)|go:""GO:1903006""(positive regulation of protein K63-linked deubiquitination)|go:""GO:1903715""(regulation of aerobic respiration)|go:""GO:1990173""(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|rcsb pdb:8FKZ|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR3|panther:PTHR14211(orthology-group)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR012160(Membrane sulphatase, HI1246-related)|interpro:IPR000917(Sulphatase)|go:""GO:0005886""(plasma membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR050448|refseq:WP_000791043.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606	rogid:cC7Eq64Gi4INgxJBzvNHb9lG6qA1392	intact-crc:C5487B017450C556|rigid:mWFVst/TnIHVbKEzzEEmSzoIuxk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZM5	uniprotkb:Q9X365	intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802.4	intact:EBI-2811711|uniprotkb:A0A0F7RN80	psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym)	psi-mi:q9x365_bacan(display_long)|uniprotkb:GBAA_pXO1_0130(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832871|imex:IM-13779-3700	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056525.2|ensembl:ENSG00000105373.19(gene)|ensembl:ENST00000246802.10(transcript)|go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002039""(p53 binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006364""(rRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0008097""(5S rRNA binding)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0039535""(regulation of RIG-I signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050821""(protein stabilization)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1901797""(negative regulation of signal transduction by p53 class mediator)|go:""GO:1901837""(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1902570""(protein localization to nucleolus)|go:""GO:1903006""(positive regulation of protein K63-linked deubiquitination)|go:""GO:1903715""(regulation of aerobic respiration)|go:""GO:1990173""(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|rcsb pdb:8FKZ|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR3|panther:PTHR14211(orthology-group)"	"refseq:NP_052791.1|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR028357|go:""GO:0000271""(polysaccharide biosynthetic process)|go:""GO:0003979""(UDP-glucose 6-dehydrogenase activity)|go:""GO:0006065""(UDP-glucuronate biosynthetic process)|go:""GO:0051287""(NAD binding)|refseq:WP_001027044.1|interpro:IPR036220|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606	rogid:DJdOP3XbPA2jandJxLQudB6VJnU1392	intact-crc:2575B95E3F70A8FF|rigid:WYvOHE3ixLkDa+voAbC0h7KvFA0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A1J9X2B2	uniprotkb:Q9NZM5	intact:EBI-2832855|uniprotkb:Q6I1D7|uniprotkb:Q6KV84|uniprotkb:E9R034|uniprotkb:E9R035|uniprotkb:Q81T55	intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802.4	psi-mi:a0a1j9x2b2_bacan(display_long)|uniprotkb:GBAA_1434(locus name)	psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832852|imex:IM-13779-3701	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0051287""(NAD binding)|interpro:IPR036291|interpro:IPR050857|refseq:WP_001062845.1"	"refseq:NP_056525.2|ensembl:ENSG00000105373.19(gene)|ensembl:ENST00000246802.10(transcript)|go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002039""(p53 binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006364""(rRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0008097""(5S rRNA binding)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0039535""(regulation of RIG-I signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050821""(protein stabilization)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1901797""(negative regulation of signal transduction by p53 class mediator)|go:""GO:1901837""(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1902570""(protein localization to nucleolus)|go:""GO:1903006""(positive regulation of protein K63-linked deubiquitination)|go:""GO:1903715""(regulation of aerobic respiration)|go:""GO:1990173""(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|rcsb pdb:8FKZ|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR3|panther:PTHR14211(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:k6ww3kSV3llt/F+WRb5g9HRO6/c1392	rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606	intact-crc:46BAA19B9EB51A84|rigid:d6EnGw9qaTTwWbIKYc/3NXmnI0A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P28799	uniprotkb:A0A6L7HG24	intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|uniprotkb:Q53Y88|uniprotkb:Q540U8|ensembl:ENSP00000053867.2|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1	intact:EBI-2811385|uniprotkb:Q6KMQ6|uniprotkb:Q6HTG4|uniprotkb:E9R169|uniprotkb:E9R170|uniprotkb:Q81M11|uniprotkb:A0A0F7R8D9	psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)	psi-mi:a0a6l7hg24_bacan(display_long)|uniprotkb:GBAA_4444(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832885|imex:IM-13779-3699	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314629""|ensembl:ENSG00000030582.19(gene)|ensembl:ENST00000053867.8(transcript)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0002282""(microglial cell activation involved in immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0007040""(lysosome organization)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0007165""(signal transduction)|go:""GO:0008083""(growth factor activity)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0060266""(negative regulation of respiratory burst involved in inflammatory response)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106016""(positive regulation of inflammatory response to wounding)|go:""GO:1900426""(positive regulation of defense response to bacterium)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1903334""(positive regulation of protein folding)|go:""GO:1903979""(negative regulation of microglial cell activation)|go:""GO:1905247""(positive regulation of aspartic-type peptidase activity)|go:""GO:1905673""(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|rcsb pdb:8T8R|rcsb pdb:8T8S|reactome:R-HSA-6798695|refseq:NP_002078.1|refseq:XP_005257310.1|dip:DIP-41742N|efo:""Orphanet:100069""|efo:""Orphanet:100070""|efo:""Orphanet:275864""|panther:PTHR12274(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR051782|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000891288.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606	rogid:/pw+ThQWZ4LMdrZ7n9sAVSfc+v41392	intact-crc:EEABE0C9F6216E01|rigid:DqzCS2iJeQ4YdxhgdMa175rymvM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HRV6	uniprotkb:Q9NZM5	intact:EBI-2832416|uniprotkb:Q6KXT9|uniprotkb:Q6I429|uniprotkb:E9R386|uniprotkb:E9R387|uniprotkb:A0A2P0H9C3|uniprotkb:Q81Z87	intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802.4	psi-mi:a0a6l7hrv6_bacan(display_long)|uniprotkb:GBAA_0385(locus name)	psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832864|imex:IM-13779-3697	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008965(Carbohydrate-binding)|interpro:IPR001919(Cellulose-binding, family II, bacterial type)|interpro:IPR011583(Chitinase II)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029070|refseq:WP_000837181.1|go:""GO:0004568""(chitinase activity)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0030247""(polysaccharide binding)|interpro:IPR012291(Cellulose-binding family II/chitobiase, carbohydrate-binding)|interpro:IPR036116|interpro:IPR050314"	"refseq:NP_056525.2|ensembl:ENSG00000105373.19(gene)|ensembl:ENST00000246802.10(transcript)|go:""GO:0000027""(ribosomal large subunit assembly)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001650""(fibrillar center)|go:""GO:0001932""(regulation of protein phosphorylation)|go:""GO:0002039""(p53 binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006364""(rRNA processing)|go:""GO:0006974""(DNA damage response)|go:""GO:0007095""(mitotic G2 DNA damage checkpoint signaling)|go:""GO:0008097""(5S rRNA binding)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0039535""(regulation of RIG-I signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050821""(protein stabilization)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1901797""(negative regulation of signal transduction by p53 class mediator)|go:""GO:1901837""(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1902570""(protein localization to nucleolus)|go:""GO:1903006""(positive regulation of protein K63-linked deubiquitination)|go:""GO:1903715""(regulation of aerobic respiration)|go:""GO:1990173""(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|rcsb pdb:8FKZ|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FLA|rcsb pdb:8FLB|rcsb pdb:8FLD|rcsb pdb:8FLE|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR3|panther:PTHR14211(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:I4hK26GFIM7C8r3ZgujTjMnow6w1392	rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606	intact-crc:F3BABC97D5B783AA|rigid:9xrbLo6lynsJ6BOsz7fAPD+l6qM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PQR9	uniprotkb:Q7Z429	intact:EBI-2828672|uniprotkb:Q6I3J2|uniprotkb:Q6KXA6|uniprotkb:E9R9P3|uniprotkb:E9R9P4|uniprotkb:Q81VA6|uniprotkb:A0A1S0QNX7|uniprotkb:A0A2P0H9W5	intact:EBI-2832909|uniprotkb:O43836|uniprotkb:B3KXM7|uniprotkb:Q8IVW7|ensembl:ENSP00000314380.5|ensembl:ENSP00000378507.4	psi-mi:a0a6l8pqr9_bacan(display_long)|uniprotkb:ald1(gene name)|psi-mi:ald1(display_short)|uniprotkb:GBAA_0592(locus name)	psi-mi:lfg1_human(display_long)|uniprotkb:GRINA(gene name)|psi-mi:GRINA(display_short)|uniprotkb:NMDARA1(gene name synonym)|uniprotkb:NMDA receptor glutamate-binding subunit(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM02(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor-associated protein 1(gene name synonym)|uniprotkb:LFG1(gene name synonym)|uniprotkb:TMBIM3(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832920|imex:IM-13779-3704	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR008141(Alanine dehydrogenase and pyridine nucleotide transhydrogenase)|go:""GO:0000166""(nucleotide binding)|go:""GO:0000286""(alanine dehydrogenase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0042853""(L-alanine catabolic process)|refseq:WP_001219742.1|interpro:IPR036291"	"refseq:NP_000828.1|refseq:NP_001009184.1|ensembl:ENSG00000178719.17(gene)|ensembl:ENST00000313269.5(transcript)|ensembl:ENST00000395068.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0016020""(membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR006214(Protein of unknown function UPF0005)|mint:Q7Z429|dip:DIP-47262N|panther:PTHR23291(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JNB2CBvULTGgpHCcdZ5+UAYw+PY1392	rogid:kI2bIry0XhRcTLqpPMnCRHjgzfM9606	intact-crc:E3A7A8EF9CDA5BDC|rigid:GgstjPWu5CntYr1XE/UnAcme2V8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HTE1	uniprotkb:P62993	intact:EBI-2815111|uniprotkb:Q6I3H0|uniprotkb:Q6KX83|uniprotkb:E9R5N7|uniprotkb:E9R5N8|uniprotkb:Q81V83|uniprotkb:A0A0F7RJ57	intact:EBI-401755|uniprotkb:P29354|uniprotkb:Q14450|uniprotkb:Q63057|uniprotkb:Q63059|ensembl:ENSP00000339007.4|ensembl:ENSP00000376345.1|ensembl:ENSP00000376347.1|ensembl:ENSP00000496913.1	psi-mi:a0a6l7hte1_bacan(display_long)|uniprotkb:GBAA_0617(locus name)	psi-mi:grb2_human(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)|uniprotkb:ASH(gene name synonym)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)|uniprotkb:Protein Ash(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832927|imex:IM-13779-3706	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000522(Bacterial transport system permease protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0033214""(siderophore-dependent iron import into cell)|refseq:WP_000760047.1|interpro:IPR037294"	"refseq:NP_002077.1|refseq:NP_987102.1|ensembl:ENSG00000177885.15(gene)|ensembl:ENST00000316804.10(transcript)|ensembl:ENST00000392562.5(transcript)|ensembl:ENST00000392564.5(transcript)|ensembl:ENST00000648046.1(transcript)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005068""(transmembrane receptor protein tyrosine kinase adaptor activity)|go:""GO:0005091""(guanyl-nucleotide exchange factor adaptor activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005168""(neurotrophin TRKA receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0008180""(COP9 signalosome)|go:""GO:0008286""(insulin receptor signaling pathway)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0012506""(vesicle membrane)|go:""GO:0014044""(Schwann cell development)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031623""(receptor internalization)|go:""GO:0035987""(endodermal cell differentiation)|go:""GO:0042110""(T cell activation)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0042552""(myelination)|go:""GO:0042770""(signal transduction in response to DNA damage)|go:""GO:0042802""(identical protein binding)|go:""GO:0043408""(regulation of MAPK cascade)|go:""GO:0043560""(insulin receptor substrate binding)|go:""GO:0045953""(negative regulation of natural killer cell mediated cytotoxicity)|go:""GO:0046875""(ephrin receptor binding)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0050853""(B cell receptor signaling pathway)|go:""GO:0060670""(branching involved in labyrinthine layer morphogenesis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070436""(Grb2-EGFR complex)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:2000379""(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|mint:P62993|rcsb pdb:1AZE|rcsb pdb:1BM2|rcsb pdb:1BMB|rcsb pdb:1CJ1|rcsb pdb:1FHS|rcsb pdb:1FYR|rcsb pdb:1GCQ|rcsb pdb:1GFC|rcsb pdb:1GFD|rcsb pdb:1GHU|rcsb pdb:1GRI|rcsb pdb:1IO6|rcsb pdb:1JYQ|rcsb pdb:1JYR|rcsb pdb:1JYU|rcsb pdb:1QG1|rcsb pdb:1TZE|rcsb pdb:1X0N|rcsb pdb:1ZFP|rcsb pdb:2AOA|rcsb pdb:2AOB|rcsb pdb:2H46|rcsb pdb:2H5K|rcsb pdb:2HUW|rcsb pdb:2VVK|rcsb pdb:2VWF|rcsb pdb:2W0Z|rcsb pdb:3C7I|rcsb pdb:3IMD|rcsb pdb:3IMJ|rcsb pdb:3IN7|rcsb pdb:3IN8|rcsb pdb:3KFJ|rcsb pdb:3MXC|rcsb pdb:3MXY|rcsb pdb:3N7Y|rcsb pdb:3N84|rcsb pdb:3N8M|rcsb pdb:3OV1|rcsb pdb:3OVE|rcsb pdb:3S8L|rcsb pdb:3S8N|rcsb pdb:3S8O|rcsb pdb:3WA4|rcsb pdb:4P9V|rcsb pdb:4P9Z|rcsb pdb:5CDW|rcsb pdb:6ICG|rcsb pdb:6ICH|rcsb pdb:6SDF|rcsb pdb:6VK2|rcsb pdb:6WM1|rcsb pdb:6WO2|rcsb pdb:7MPH|rcsb pdb:8DGO|reactome:R-HSA-109704|reactome:R-HSA-112412|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-167044|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2029482|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354194|reactome:R-HSA-375165|reactome:R-HSA-388841|reactome:R-HSA-389359|reactome:R-HSA-391160|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8853659|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8865999|reactome:R-HSA-8875360|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8983432|reactome:R-HSA-9013420|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028335|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9645135|reactome:R-HSA-9664422|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9680350|reactome:R-HSA-9702518|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-9725370|reactome:R-HSA-983695|reactome:R-HSA-9842663|dip:DIP-29229N|panther:PTHR46037(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:39ISyYq8ial8lW93YYDqnxGY+ZE1392	rogid:SLnslQ7NHbnuK06nMVuRvJpoOA49606	intact-crc:022BF3BEE8BAC1AE|rigid:hpum5VVgPSKRgweRMTaLR4aQLuI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z429	uniprotkb:A0A6L8PFQ4	intact:EBI-2832909|uniprotkb:O43836|uniprotkb:B3KXM7|uniprotkb:Q8IVW7|ensembl:ENSP00000314380.5|ensembl:ENSP00000378507.4	intact:EBI-2811194|uniprotkb:Q6KKD9|uniprotkb:Q6HR20|uniprotkb:E9RDA5|uniprotkb:E9RDA6|uniprotkb:Q81X84|uniprotkb:A0A0F7R5R3	psi-mi:lfg1_human(display_long)|uniprotkb:GRINA(gene name)|psi-mi:GRINA(display_short)|uniprotkb:NMDARA1(gene name synonym)|uniprotkb:NMDA receptor glutamate-binding subunit(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM02(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor-associated protein 1(gene name synonym)|uniprotkb:LFG1(gene name synonym)|uniprotkb:TMBIM3(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 3(gene name synonym)	psi-mi:a0a6l8pfq4_bacan(display_long)|uniprotkb:GBAA_5358(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832906|imex:IM-13779-3703	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_000828.1|refseq:NP_001009184.1|ensembl:ENSG00000178719.17(gene)|ensembl:ENST00000313269.5(transcript)|ensembl:ENST00000395068.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0016020""(membrane)|go:""GO:0032469""(endoplasmic reticulum calcium ion homeostasis)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1902236""(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR006214(Protein of unknown function UPF0005)|mint:Q7Z429|dip:DIP-47262N|panther:PTHR23291(orthology-group)"	interpro:IPR006944(Phage portal protein)|interpro:IPR006427(Phage portal protein, HK97)|refseq:WP_000522484.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kI2bIry0XhRcTLqpPMnCRHjgzfM9606	rogid:dfclSVwADmsN1LvBduNOVnRZ0DA1392	intact-crc:DD0C98350BCE2FD5|rigid:GdngV82Pu1NyM0wlV78L5vSUMvQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81P27	uniprotkb:P28799	intact:EBI-2814639|uniprotkb:Q6KRC1|uniprotkb:Q6HX99	intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|uniprotkb:Q53Y88|uniprotkb:Q540U8|ensembl:ENSP00000053867.2|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1	psi-mi:proa_bacan(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:BA_2992(locus name)|uniprotkb:GBAA_2992(locus name)|uniprotkb:BAS2781(locus name)	psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832899|imex:IM-13779-3705	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|go:""GO:0004350""(glutamate-5-semialdehyde dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0050661""(NADP binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:NP_845325.1|refseq:YP_029039.1|refseq:WP_001006638.1"	"efo:""Orphanet:314629""|ensembl:ENSG00000030582.19(gene)|ensembl:ENST00000053867.8(transcript)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0002282""(microglial cell activation involved in immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0007040""(lysosome organization)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0007165""(signal transduction)|go:""GO:0008083""(growth factor activity)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0060266""(negative regulation of respiratory burst involved in inflammatory response)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106016""(positive regulation of inflammatory response to wounding)|go:""GO:1900426""(positive regulation of defense response to bacterium)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1903334""(positive regulation of protein folding)|go:""GO:1903979""(negative regulation of microglial cell activation)|go:""GO:1905247""(positive regulation of aspartic-type peptidase activity)|go:""GO:1905673""(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|rcsb pdb:8T8R|rcsb pdb:8T8S|reactome:R-HSA-6798695|refseq:NP_002078.1|refseq:XP_005257310.1|dip:DIP-41742N|efo:""Orphanet:100069""|efo:""Orphanet:100070""|efo:""Orphanet:275864""|panther:PTHR12274(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:2iR76/3cLX7gyVDMLNG2KEyBoMY1392	rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606	intact-crc:2534E45F3E981E41|rigid:EcgI5x7Inv5psJml1JWjD1KCJUE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P28799	uniprotkb:A0A6L8PXW6	intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|uniprotkb:Q53Y88|uniprotkb:Q540U8|ensembl:ENSP00000053867.2|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1	intact:EBI-2821561|uniprotkb:Q6KLX3|uniprotkb:Q6HSM8|uniprotkb:E9R3W7|uniprotkb:E9R3W8|uniprotkb:Q81L77|uniprotkb:A0A0F7RCR3	psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)	psi-mi:a0a6l8pxw6_bacan(display_long)|uniprotkb:sdhA(gene name)|psi-mi:sdhA(display_short)|uniprotkb:GBAA_4754(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832892|imex:IM-13779-3702	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:314629""|ensembl:ENSG00000030582.19(gene)|ensembl:ENST00000053867.8(transcript)|go:""GO:0002265""(astrocyte activation involved in immune response)|go:""GO:0002282""(microglial cell activation involved in immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0007040""(lysosome organization)|go:""GO:0007041""(lysosomal transport)|go:""GO:0007042""(lysosomal lumen acidification)|go:""GO:0007165""(signal transduction)|go:""GO:0008083""(growth factor activity)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016020""(membrane)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043525""(positive regulation of neuron apoptotic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0060266""(negative regulation of respiratory burst involved in inflammatory response)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106016""(positive regulation of inflammatory response to wounding)|go:""GO:1900426""(positive regulation of defense response to bacterium)|go:""GO:1902564""(negative regulation of neutrophil activation)|go:""GO:1903334""(positive regulation of protein folding)|go:""GO:1903979""(negative regulation of microglial cell activation)|go:""GO:1905247""(positive regulation of aspartic-type peptidase activity)|go:""GO:1905673""(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|rcsb pdb:8T8R|rcsb pdb:8T8S|reactome:R-HSA-6798695|refseq:NP_002078.1|refseq:XP_005257310.1|dip:DIP-41742N|efo:""Orphanet:100069""|efo:""Orphanet:100070""|efo:""Orphanet:275864""|panther:PTHR12274(orthology-group)"	"interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR011280(Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria)|interpro:IPR027477|go:""GO:0000104""(succinate dehydrogenase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0009055""(electron transfer activity)|go:""GO:0009061""(anaerobic respiration)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_000676736.1|interpro:IPR036188|interpro:IPR037099|interpro:IPR030664"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606	rogid:B95N82A5rfkh7/mfJ2A2PxqfcBM1392	intact-crc:8D7712AB9A905C9C|rigid:hT0JBAsK7OUNx3b9HHYW/hTeQdA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P22352	uniprotkb:A0A2B8HUE3	intact:EBI-2832946|ensembl:ENSP00000373477.4|uniprotkb:Q9NZ74|uniprotkb:Q86W78|uniprotkb:Q9UEL1|uniprotkb:O43787	intact:EBI-2819959|uniprotkb:Q6KM19|uniprotkb:Q6HSS6|uniprotkb:E9R825|uniprotkb:E9R826|uniprotkb:Q81LC3|uniprotkb:A0A1J9WT69|uniprotkb:A0A0J1HLH6	psi-mi:gpx3_human(display_long)|uniprotkb:GPX3(gene name)|psi-mi:GPX3(display_short)|uniprotkb:GPXP(gene name synonym)|uniprotkb:Extracellular glutathione peroxidase(gene name synonym)|uniprotkb:Plasma glutathione peroxidase(gene name synonym)	psi-mi:a0a2b8hue3_bacan(display_long)|uniprotkb:GBAA_4700(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832954|imex:IM-13779-3707	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000211445.13(gene)|ensembl:ENST00000388825.9(transcript)|go:""GO:0004602""(glutathione peroxidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006982""(response to lipid hydroperoxide)|go:""GO:0008430""(selenium binding)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|mint:P22352|rcsb pdb:2R37|reactome:R-HSA-3299685|refseq:NP_002075.2|refseq:NP_001316719.1|panther:PTHR11592(orthology-group)"	"interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR019953|interpro:IPR003718(OsmC-like protein)|go:""GO:0006979""(response to oxidative stress)|refseq:WP_000359781.1|interpro:IPR036102"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:20fuL/QpCWDjlBCXTTjdzbb1kbY9606	rogid:IoB2qQAd8rUVYA4SbsvV4/TWwBo1392	intact-crc:4B3CA9F452DD8B7E|rigid:3BPD05unJK5TRPJvkBZTIfgBDs4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96HH9	uniprotkb:A0A6L8PD01	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689.3	intact:EBI-2810689|uniprotkb:Q6KR00|uniprotkb:Q6HWW8|uniprotkb:E9QQS7|uniprotkb:E9QQS8|uniprotkb:Q81NP8	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:a0a6l8pd01_bacan(display_long)|uniprotkb:GBAA_3131(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832934|imex:IM-13779-3709	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|refseq:XP_016865274.1|ensembl:ENSG00000155324.10(gene)|ensembl:ENST00000285689.8(transcript)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0042802""(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR052633|mint:Q96HH9|panther:PTHR46645(orthology-group)"	"interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR036291|refseq:WP_000649082.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	rogid:zX4+aIdzhDeWoVC9l0OlbVnHVow1392	intact-crc:51413601250038ED|rigid:kOZwtgO6PikC2Vr7Xdnftr2/xT8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WK3	uniprotkb:P22352	intact:EBI-2826194|uniprotkb:Q6KNY5|uniprotkb:Q6HUQ4	intact:EBI-2832946|ensembl:ENSP00000373477.4|uniprotkb:Q9NZ74|uniprotkb:Q86W78|uniprotkb:Q9UEL1|uniprotkb:O43787	"psi-mi:trmfo_bacan(display_long)|uniprotkb:trmFO(gene name)|psi-mi:trmFO(display_short)|uniprotkb:gid(gene name synonym)|uniprotkb:""Folate-dependent tRNA (uracil-5-)-methyltransferase""(gene name synonym)|uniprotkb:""Folate-dependent tRNA(M-5-U54)-methyltransferase""(gene name synonym)|uniprotkb:BA_3970(locus name)|uniprotkb:GBAA_3970(locus name)|uniprotkb:BAS3683(locus name)"	psi-mi:gpx3_human(display_long)|uniprotkb:GPX3(gene name)|psi-mi:GPX3(display_short)|uniprotkb:GPXP(gene name synonym)|uniprotkb:Extracellular glutathione peroxidase(gene name synonym)|uniprotkb:Plasma glutathione peroxidase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832961|imex:IM-13779-3708	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004417(Gid protein)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0047151""(""tRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent"")|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|interpro:IPR040131|refseq:NP_846213.1|refseq:YP_029934.1|refseq:WP_003161605.1"	"ensembl:ENSG00000211445.13(gene)|ensembl:ENST00000388825.9(transcript)|go:""GO:0004602""(glutathione peroxidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006982""(response to lipid hydroperoxide)|go:""GO:0008430""(selenium binding)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|mint:P22352|rcsb pdb:2R37|reactome:R-HSA-3299685|refseq:NP_002075.2|refseq:NP_001316719.1|panther:PTHR11592(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZK5+I3fqFuyTXl2yUtsPcns5frI1392	rogid:20fuL/QpCWDjlBCXTTjdzbb1kbY9606	intact-crc:9B8614268D3424AF|rigid:rS4AzTHhkQQetEQGU9Y5jn4XEK4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PDB5	uniprotkb:Q96I76	intact:EBI-2832975|uniprotkb:Q6HWP3|uniprotkb:Q6KQT6|uniprotkb:E9RD25|uniprotkb:E9RD26|uniprotkb:Q81NI0|uniprotkb:A0A0F7RGP3	intact:EBI-2832968|uniprotkb:Q8NDJ2|uniprotkb:Q5JYH2|uniprotkb:Q9H9Z3|ensembl:ENSP00000354645.5	psi-mi:a0a6l8pdb5_bacan(display_long)|uniprotkb:GBAA_3213(locus name)	psi-mi:gptc3_human(display_long)|uniprotkb:GPATCH3(gene name)|psi-mi:GPATCH3(display_short)|uniprotkb:GPATC3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832980|imex:IM-13779-3710	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002293(Amino acid/polyamine transporter I)|refseq:WP_000790602.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR050367"	"refseq:NP_071361.2|ensembl:ENSG00000198746.13(gene)|ensembl:ENST00000361720.10(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0039536""(negative regulation of RIG-I signaling pathway)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|interpro:IPR000467(D111/G-patch)|interpro:IPR040341|panther:PTHR14390(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5Ag4uBvJTjse75hEGGRn1PlNM6Y1392	rogid:fxhi1PBMX09VGLJQxDsgsxzdXAs9606	intact-crc:1F8866D2A3FD769C|rigid:lvpJ6r7+5fGmiSRaI9Fhav5VBRU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P242	uniprotkb:Q9Y653	intact:EBI-2821152|uniprotkb:Q6HUC1|uniprotkb:Q6KNK8|uniprotkb:E9RCL6|uniprotkb:E9RCL7|uniprotkb:Q81W74|uniprotkb:A0A0F7RDJ6	intact:EBI-2833004|ensembl:ENSP00000454933.2|ensembl:ENSP00000455215.1|ensembl:ENSP00000456794.1|ensembl:ENSP00000500185.2|uniprotkb:A6NIT7|uniprotkb:O95966|uniprotkb:Q96HB4|uniprotkb:A6NJV9|uniprotkb:B0M0K4|uniprotkb:Q8NGB3|uniprotkb:B4DR54|uniprotkb:Q6ZMP1	psi-mi:a0a6l8p242_bacan(display_long)|uniprotkb:GBAA_4108(locus name)	psi-mi:agrg1_human(display_long)|uniprotkb:ADGRG1(gene name)|psi-mi:ADGRG1(display_short)|uniprotkb:G-protein coupled receptor 56(gene name synonym)|uniprotkb:GPR56(gene name synonym)|uniprotkb:Protein TM7XN1(gene name synonym)|uniprotkb:TM7LN4(gene name synonym)|uniprotkb:TM7XN1(gene name synonym)|uniprotkb:UNQ540/PRO1083(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833001|imex:IM-13779-3714	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR028985|refseq:WP_000065132.1|interpro:IPR041270	"ensembl:ENSG00000205336.14(gene)|ensembl:ENST00000565976.6(transcript)|ensembl:ENST00000567835.5(transcript)|ensembl:ENST00000568909.5(transcript)|ensembl:ENST00000673126.2(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005518""(collagen binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0007200""(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007420""(brain development)|go:""GO:0008201""(heparin binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0016477""(cell migration)|go:""GO:0021796""(cerebral cortex regionalization)|go:""GO:0021801""(cerebral cortex radial glia-guided migration)|go:""GO:0021819""(layer formation in cerebral cortex)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0045121""(membrane raft)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0061351""(neural precursor cell proliferation)|go:""GO:0061484""(hematopoietic stem cell homeostasis)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072520""(seminiferous tubule development)|go:""GO:0097451""(glial limiting end-foot)|go:""GO:1900748""(positive regulation of vascular endothelial growth factor signaling pathway)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|go:""GO:2001223""(negative regulation of neuron migration)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR003910(GPCR, family 2, orphan receptor, GPR56)|interpro:IPR017981|interpro:IPR040679|interpro:IPR040950|interpro:IPR046338|mint:Q9Y653|rcsb pdb:7SF8|refseq:NP_001139242.1|refseq:NP_001139243.1|refseq:NP_001139244.1|refseq:NP_001139245.1|refseq:NP_001139246.1|refseq:NP_001277071.1|refseq:NP_001277072.1|refseq:NP_005673.3|refseq:NP_958932.1|refseq:NP_958933.1|refseq:XP_005256303.1|refseq:XP_005256304.1|refseq:XP_005256305.1|refseq:XP_005256306.1|refseq:XP_005256308.1|refseq:XP_005256309.1|refseq:XP_005256311.1|refseq:XP_005256312.1|refseq:XP_006721405.1|refseq:XP_006721406.1|refseq:XP_006721407.1|refseq:XP_006721408.1|refseq:XP_006721409.1|refseq:XP_006721410.1|refseq:XP_011521765.1|refseq:XP_011521766.1|refseq:XP_011521767.1|refseq:XP_011521768.1|refseq:XP_011521769.1|refseq:XP_011521770.1|refseq:XP_016879381.1|efo:""Orphanet:101070""|efo:""Orphanet:98889""|panther:PTHR12011(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:F4z1OBx8X2SzPlB7SF8B4YTdXRI1392	rogid:9qQ17yz9lj2N2J/NQ4UBOL3z/h09606	intact-crc:61B3CB612855B29E|rigid:FEJdVRP0EVWQNzbeJ8ydZDtZ0bE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HHX2	uniprotkb:Q99527	intact:EBI-2812285|uniprotkb:Q6KUB0|uniprotkb:Q6I0E0|uniprotkb:E9QSI8|uniprotkb:E9QSI9|uniprotkb:Q81S59|uniprotkb:A0A0F7RKM4	intact:EBI-2833021|ensembl:ENSP00000297469.3|ensembl:ENSP00000380277.3|ensembl:ENSP00000380281.1|ensembl:ENSP00000385151.1|uniprotkb:O43494|uniprotkb:O00143|uniprotkb:Q99981|uniprotkb:A8K6C5|uniprotkb:Q96F42|uniprotkb:Q6FHL1|uniprotkb:Q13631|uniprotkb:B5BUJ1	psi-mi:a0a6l7hhx2_bacan(display_long)|uniprotkb:GBAA_1815(locus name)	psi-mi:gper1_human(display_long)|uniprotkb:GPER1(gene name)|psi-mi:GPER1(display_short)|uniprotkb:CEPR(gene name synonym)|uniprotkb:CMKRL2(gene name synonym)|uniprotkb:Chemoattractant receptor-like 2(gene name synonym)|uniprotkb:DRY12(gene name synonym)|uniprotkb:Flow-induced endothelial G-protein coupled receptor 1(gene name synonym)|uniprotkb:G protein-coupled estrogen receptor 1(gene name synonym)|uniprotkb:G-protein coupled receptor 30(gene name synonym)|uniprotkb:GPCR-Br(gene name synonym)|uniprotkb:GPER(gene name synonym)|uniprotkb:GPR30(gene name synonym)|uniprotkb:IL8-related receptor DRY12(gene name synonym)|uniprotkb:Lymphocyte-derived G-protein coupled receptor(gene name synonym)|uniprotkb:Membrane estrogen receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833018|imex:IM-13779-3712	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR025450|go:""GO:0016020""(membrane)|refseq:WP_000789548.1"	"ensembl:ENSG00000164850.16(gene)|ensembl:ENST00000297469.3(transcript)|ensembl:ENST00000397088.4(transcript)|ensembl:ENST00000397092.5(transcript)|ensembl:ENST00000401670.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001956""(positive regulation of neurotransmitter secretion)|go:""GO:0002695""(negative regulation of leukocyte activation)|go:""GO:0003682""(chromatin binding)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005496""(steroid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0007204""(positive regulation of cytosolic calcium ion concentration)|go:""GO:0007399""(nervous system development)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010948""(negative regulation of cell cycle process)|go:""GO:0014069""(postsynaptic density)|go:""GO:0019228""(neuronal action potential)|go:""GO:0030154""(cell differentiation)|go:""GO:0030263""(apoptotic chromosome condensation)|go:""GO:0030264""(nuclear fragmentation involved in apoptotic nuclear change)|go:""GO:0030284""(nuclear estrogen receptor activity)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0030425""(dendrite)|go:""GO:0030518""(nuclear receptor-mediated steroid hormone signaling pathway)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032591""(dendritic spine membrane)|go:""GO:0032962""(positive regulation of inositol trisphosphate biosynthetic process)|go:""GO:0038054""(G protein-coupled estrogen receptor activity)|go:""GO:0042311""(vasodilation)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043401""(steroid hormone receptor signaling pathway)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043679""(axon terminus)|go:""GO:0044327""(dendritic spine head)|go:""GO:0045087""(innate immune response)|go:""GO:0045095""(keratin filament)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045742""(positive regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0045745""(positive regulation of G protein-coupled receptor signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050769""(positive regulation of neurogenesis)|go:""GO:0051055""(negative regulation of lipid biosynthetic process)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055037""(recycling endosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070474""(positive regulation of uterine smooth muscle contraction)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0071389""(cellular response to mineralocorticoid stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1990239""(steroid hormone binding)|go:""GO:2000353""(positive regulation of endothelial cell apoptotic process)|go:""GO:2000724""(positive regulation of cardiac vascular smooth muscle cell differentiation)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR047143|rcsb pdb:8XOF|rcsb pdb:8XOG|rcsb pdb:8XOH|rcsb pdb:8XOI|rcsb pdb:8XOJ|reactome:R-HSA-375276|reactome:R-HSA-418594|reactome:R-HSA-9634597|refseq:NP_001035055.1|refseq:NP_001091671.1|refseq:NP_001496.1|panther:PTHR24226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:g0iSNc7Mh4tgNaBj+nHYsEjH5sY1392	rogid:eSjZkUft0qAyBW0G2wsKEmwgsJw9606	intact-crc:E698B8968AB72001|rigid:dPa/LXvfl2UNHVma5RS0HCgIuEE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13227	uniprotkb:A0A6L8P6L1	intact:EBI-713355|uniprotkb:Q6FHM8|ensembl:ENSP00000370104.2|ensembl:ENSP00000379841.4|ensembl:ENSP00000500255.1|ensembl:ENSP00000500677.1|uniprotkb:B4DXA1	intact:EBI-2809878|uniprotkb:Q6I3Z2|uniprotkb:Q6KXQ4|uniprotkb:E9R1Y7|uniprotkb:E9R1Y8|uniprotkb:Q81Z52|uniprotkb:A0A0F7RMG3	psi-mi:gps2_human(display_long)|uniprotkb:GPS2(gene name)|psi-mi:GPS2(display_short)	psi-mi:a0a6l8p6l1_bacan(display_long)|uniprotkb:GBAA_0421(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832987|imex:IM-13779-3715	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004480.1|ensembl:ENSG00000132522.16(gene)|ensembl:ENSG00000288325.1(gene)|ensembl:ENST00000380728.7(transcript)|ensembl:ENST00000389167.9(transcript)|ensembl:ENST00000672046.1(transcript)|ensembl:ENST00000673265.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007254""(JNK cascade)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030332""(cyclin binding)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0035360""(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:""GO:0045598""(regulation of fat cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0098780""(response to mitochondrial depolarisation)|go:""GO:1900045""(negative regulation of protein K63-linked ubiquitination)|interpro:IPR026094|mint:Q13227|rcsb pdb:2L5G|reactome:R-HSA-1989781|reactome:R-HSA-3214815|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9841922|dip:DIP-34427N|panther:PTHR22654(orthology-group)"	"interpro:IPR007197(Radical SAM)|interpro:IPR014866(YfkB-like domain)|interpro:IPR013785(Aldolase-type TIM barrel)|go:""GO:0003824""(catalytic activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR031004|refseq:WP_000156003.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:zMNwbPfMT2dBTxgcwiMD92QHJtM9606	rogid:BSJ0SMeZprDBEfO9AnyN2+GNdiI1392	intact-crc:65150C13530D3B0A|rigid:gj82jQmvFhY11vwc/ho8gHJQdg4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2P0HLQ6	uniprotkb:Q13227	intact:EBI-2816435	intact:EBI-713355|uniprotkb:Q6FHM8|ensembl:ENSP00000370104.2|ensembl:ENSP00000379841.4|ensembl:ENSP00000500255.1|ensembl:ENSP00000500677.1|uniprotkb:B4DXA1	psi-mi:a0a2p0hlq6_bacan(display_long)|uniprotkb:Homoserine transacetylase(gene name synonym)|uniprotkb:metAA(gene name synonym)|uniprotkb:metA(gene name)|psi-mi:metA(display_short)|uniprotkb:BA_5655(locus name)	psi-mi:gps2_human(display_long)|uniprotkb:GPS2(gene name)|psi-mi:GPS2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2832994|imex:IM-13779-3711	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:Q81JP7(uniprot-removed-ac)|interpro:IPR005697(Homoserine O-succinyltransferase)|interpro:IPR029062|interpro:IPR033752|refseq:NP_847803.2|refseq:WP_001121524.1|go:""GO:0004414""(homoserine O-acetyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0008899""(homoserine O-succinyltransferase activity)|go:""GO:0019281""(L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine)"	"refseq:NP_004480.1|ensembl:ENSG00000132522.16(gene)|ensembl:ENSG00000288325.1(gene)|ensembl:ENST00000380728.7(transcript)|ensembl:ENST00000389167.9(transcript)|ensembl:ENST00000672046.1(transcript)|ensembl:ENST00000673265.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005095""(GTPase inhibitor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007254""(JNK cascade)|go:""GO:0010804""(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0010875""(positive regulation of cholesterol efflux)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019216""(regulation of lipid metabolic process)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030332""(cyclin binding)|go:""GO:0034122""(negative regulation of toll-like receptor signaling pathway)|go:""GO:0035360""(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:""GO:0045598""(regulation of fat cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046329""(negative regulation of JNK cascade)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050859""(negative regulation of B cell receptor signaling pathway)|go:""GO:0098780""(response to mitochondrial depolarisation)|go:""GO:1900045""(negative regulation of protein K63-linked ubiquitination)|interpro:IPR026094|mint:Q13227|rcsb pdb:2L5G|reactome:R-HSA-1989781|reactome:R-HSA-3214815|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9841922|dip:DIP-34427N|panther:PTHR22654(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:UJL5FHiePk68PGCRnU7vx9nZmy41392	rogid:zMNwbPfMT2dBTxgcwiMD92QHJtM9606	intact-crc:D220356E356F9EEC|rigid:Wco4svBJiViRkb3DJPv3SniDEqw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81KT8	uniprotkb:P13224	intact:EBI-2809955|uniprotkb:Q6KLJ1|uniprotkb:Q6HS94	intact:EBI-2833037|uniprotkb:Q8NG40|uniprotkb:Q14422|ensembl:ENSP00000383382.2	psi-mi:ezra_bacan(display_long)|uniprotkb:ezrA(gene name)|psi-mi:ezrA(display_short)|uniprotkb:BA_4901(locus name)|uniprotkb:GBAA_4901(locus name)|uniprotkb:BAS4547(locus name)	psi-mi:gp1bb_human(display_long)|uniprotkb:GP1BB(gene name)|psi-mi:GP1BB(display_short)|uniprotkb:Antigen CD42b-beta(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833043|imex:IM-13779-3713	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010379(Septation ring formation regulator, EzrA)|refseq:WP_000377289.1|go:""GO:0000917""(division septum assembly)|go:""GO:0000921""(septin ring assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0005940""(septin ring)|refseq:NP_847100.1|refseq:YP_030794.1"	"efo:""Orphanet:140957""|efo:""Orphanet:274""|efo:""Orphanet:567""|efo:""Orphanet:853""|ensembl:ENSG00000203618.6(gene)|ensembl:ENST00000366425.4(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007597""(blood coagulation, intrinsic pathway)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0030168""(platelet activation)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042802""(identical protein binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:1990779""(glycoprotein Ib-IX-V complex)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR032675|interpro:IPR052313|mint:P13224|rcsb pdb:3REZ|rcsb pdb:3RFE|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|reactome:R-HSA-9845620|reactome:R-HSA-9846298|refseq:NP_000398.1|panther:PTHR22650(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6MFyaajo44S7ZHEdxIvx28fZmkY1392	rogid:eD4E+gbGDmXWJhX5W8jNjLLy0d89606	intact-crc:03B0C9B6DCC25A6B|rigid:dvaDne8pexPkSocTG36dDLWTr5A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HD26	uniprotkb:A0A6L7H421	intact:EBI-349832|uniprotkb:A6NM30|uniprotkb:Q59FS4|uniprotkb:Q969U8|ensembl:ENSP00000357484.2	intact:EBI-2810652|uniprotkb:Q6KSG7|uniprotkb:Q6HYF9|uniprotkb:E9R9F4|uniprotkb:E9R9F5|uniprotkb:Q81Q87|uniprotkb:A0A0F7RDV9	psi-mi:gopc_human(display_long)|uniprotkb:CAL(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)	psi-mi:a0a6l7h421_bacan(display_long)|uniprotkb:GBAA_2546(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833057|imex:IM-13779-3719	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000047932.14(gene)|ensembl:ENST00000368498.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006893""(Golgi to plasma membrane transport)|go:""GO:0010360""(negative regulation of anion channel activity)|go:""GO:0014069""(postsynaptic density)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0030140""(trans-Golgi network transport vesicle)|go:""GO:0030425""(dendrite)|go:""GO:0030660""(Golgi-associated vesicle membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045176""(apical protein localization)|go:""GO:0140313""(molecular sequestering activity)|go:""GO:2000009""(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR038879|mint:Q9HD26|rcsb pdb:2DC2|rcsb pdb:2LOB|rcsb pdb:4E34|rcsb pdb:4E35|rcsb pdb:4JOE|rcsb pdb:4JOF|rcsb pdb:4JOG|rcsb pdb:4JOH|rcsb pdb:4JOJ|rcsb pdb:4JOK|rcsb pdb:4JOP|rcsb pdb:4JOR|rcsb pdb:4K6Y|rcsb pdb:4K72|rcsb pdb:4K75|rcsb pdb:4K76|rcsb pdb:4K78|rcsb pdb:4NMO|rcsb pdb:4NMP|rcsb pdb:4NMQ|rcsb pdb:4NMR|rcsb pdb:4NMS|rcsb pdb:4NMT|rcsb pdb:4NMV|rcsb pdb:4Q6H|rcsb pdb:4Q6S|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6OV7|rcsb pdb:6V84|rcsb pdb:6XNJ|rcsb pdb:7JZO|rcsb pdb:7JZP|rcsb pdb:7JZQ|rcsb pdb:7JZR|reactome:R-HSA-5627083|reactome:R-HSA-9013406|refseq:NP_001017408.1|refseq:NP_065132.1|panther:PTHR16528(orthology-group)|efo:""Orphanet:171709"""	interpro:IPR013560(Protein of unknown function DUF1722)|interpro:IPR007553(Protein of unknown function DUF523)|interpro:IPR017087(Uncharacterised conserved protein UCP037004)|refseq:WP_001248630.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bXzu5wvJifZwB+Q52cgC4tZQl/k9606	rogid:2helogO2D/G85c/K2apFD3gNVOc1392	intact-crc:5E4494187DD20D9D|rigid:r17F68csUBZYXyPhZVtz/+/AOJQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H8Y8	uniprotkb:Q81LD0	intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|uniprotkb:B4DKT0|intact:EBI-28970723|ensembl:ENSP00000234160.4	intact:EBI-2809803|uniprotkb:Q6KM26|uniprotkb:Q6HST3	psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym)	psi-mi:gsa2_bacan(display_long)|uniprotkb:hemL2(gene name)|psi-mi:hemL2(display_short)|uniprotkb:Glutamate-1-semialdehyde aminotransferase 2(gene name synonym)|uniprotkb:BA_4693(locus name)|uniprotkb:GBAA_4693(locus name)|uniprotkb:BAS4358(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833050|imex:IM-13779-3720	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806.13(gene)|ensembl:ENST00000234160.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0006996""(organelle organization)|go:""GO:0007030""(Golgi organization)|go:""GO:0007283""(spermatogenesis)|go:""GO:0016020""(membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0061951""(establishment of protein localization to plasma membrane)|go:""GO:0070925""(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658|panther:PTHR12893(orthology-group)"	"interpro:IPR004639(Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|rcsb pdb:3K28|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0042286""(glutamate-1-semialdehyde 2,1-aminomutase activity)|refseq:WP_001224513.1|refseq:NP_846906.1|refseq:YP_030605.1|interpro:IPR049704"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xSy3HsObmteg/doer5eLoZiz+fU9606	rogid:GnZPBZpKvZpcwazgpwseq6iVQbg1392	intact-crc:0139DD2E58142AC3|rigid:vPL/BhYdIJBBLniMJdxN/3UC1UM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1WFU0	uniprotkb:Q03113	intact:EBI-2833090|uniprotkb:Q6KX40|uniprotkb:Q6I3C4|uniprotkb:E9R0N2|uniprotkb:E9R0N3|uniprotkb:Q81V40|uniprotkb:A0A1J9V4P0	intact:EBI-2833081|ensembl:ENSP00000275364.3|ensembl:ENSP00000520443.1|uniprotkb:Q2T9L1|uniprotkb:Q8TD71|uniprotkb:Q86UM8|uniprotkb:Q9UDU9|uniprotkb:A4D204|uniprotkb:B3KXS2|uniprotkb:B7Z3F7|uniprotkb:Q5PPR5	psi-mi:a0a4y1wfu0_bacan(display_long)|uniprotkb:GBAA_0662(locus name)	psi-mi:gna12_human(display_long)|uniprotkb:GNA12(gene name)|psi-mi:GNA12(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833078|imex:IM-13779-3717	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR000835(Bacterial regulatory protein, MarR)|refseq:WP_001132360.1|interpro:IPR036388|interpro:IPR036390"	"ensembl:ENSG00000146535.15(gene)|ensembl:ENST00000275364.8(transcript)|ensembl:ENST00000715274.1(transcript)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003924""(GTPase activity)|go:""GO:0003925""(G protein activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005834""(heterotrimeric G-protein complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007188""(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0007596""(blood coagulation)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0010762""(regulation of fibroblast migration)|go:""GO:0016328""(lateral plasma membrane)|go:""GO:0030154""(cell differentiation)|go:""GO:0031526""(brush border membrane)|go:""GO:0031683""(G-protein beta/gamma-subunit complex binding)|go:""GO:0031752""(D5 dopamine receptor binding)|go:""GO:0032006""(regulation of TOR signaling)|go:""GO:0032434""(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0042733""(embryonic digit morphogenesis)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0046872""(metal ion binding)|go:""GO:0051721""(protein phosphatase 2A binding)|go:""GO:0072542""(protein phosphatase activator activity)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904753""(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019(""Guanine nucleotide binding protein (G-protein), alpha subunit"")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:Q03113|rcsb pdb:7YDJ|reactome:R-HSA-416482|reactome:R-HSA-456926|refseq:NP_031379.2|refseq:NP_001269370.1|refseq:NP_001280021.1|panther:PTHR10218(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wJyyf7x0gaTKypUFVSrl7uzDz/41392	rogid:iuIDldvBlG+r+jg59e3QSNbcvtY9606	intact-crc:52787F28B8D53FC2|rigid:xih8u5eZ0TDgj0Q88LJY1vLdB7g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q86XS8	uniprotkb:A0A6L7HLZ2	intact:EBI-719861|uniprotkb:Q32P32|uniprotkb:Q641P9|uniprotkb:Q6P177|uniprotkb:Q7L2U2|uniprotkb:Q9P0J9|ensembl:ENSP00000430237.1|intact:EBI-2129193|uniprotkb:J3KN31|uniprotkb:Q59EL1	intact:EBI-2822704|uniprotkb:Q6I1V2|uniprotkb:Q6KVP4|uniprotkb:E9QXG7|uniprotkb:E9QXG8|uniprotkb:Q81TM2|uniprotkb:A0A0F7RFK1	psi-mi:goli_human(display_long)|uniprotkb:RING finger protein 130(gene name synonym)|uniprotkb:RNF130(gene name)|psi-mi:RNF130(display_short)|uniprotkb:Goliath homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF130(gene name synonym)	psi-mi:a0a6l7hlz2_bacan(display_long)|uniprotkb:GBAA_1249(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833071|imex:IM-13779-3718	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001267730.1|refseq:NP_060904.2|ensembl:ENSG00000113269.14(gene)|ensembl:ENST00000521389.6(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0012501""(programmed cell death)|go:""GO:0016020""(membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR046450|interpro:IPR051834|mint:Q86XS8|reactome:R-HSA-983168|panther:PTHR22765(orthology-group)"	"interpro:IPR006221(Glutamine amidotransferase of anthranilate synthase)|interpro:IPR017926|interpro:IPR029062|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004049""(anthranilate synthase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006541""(glutamine metabolic process)|refseq:WP_000636353.1|interpro:IPR050472"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OpFZYE55FFPN28YeaGOPtm4HFIc9606	rogid:VEw7iORueUYyEAibcEuigksbFMo1392	intact-crc:7E63E7AD5060CA43|rigid:P6KTOMtB4RYWNS54P09mTwBTNG4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H9D5	uniprotkb:Q8NBJ4	intact:EBI-2814246	intact:EBI-712073|uniprotkb:Q6IAF4|uniprotkb:Q9NRB9|ensembl:ENSP00000373363.3|ensembl:ENSP00000373364.3	psi-mi:a0a6l7h9d5_bacan(display_long)|uniprotkb:BA_5677(locus name)	psi-mi:golm1_human(display_long)|uniprotkb:Golgi phosphoprotein 2(gene name synonym)|uniprotkb:Golgi membrane protein GP73(gene name synonym)|uniprotkb:GOLM1(gene name)|psi-mi:GOLM1(display_short)|uniprotkb:PSEC0242(orf name)|uniprotkb:UNQ686/PRO1326(orf name)|uniprotkb:GOLPH2(gene name synonym)|uniprotkb:C9orf155(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833064|imex:IM-13779-3716	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:Q81JM6(uniprot-removed-ac)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|refseq:NP_847824.2|refseq:WP_000672693.1|go:""GO:0016757""(glycosyltransferase activity)|interpro:IPR050834"	"ensembl:ENSG00000135052.16(gene)|ensembl:ENST00000388711.7(transcript)|ensembl:ENST00000388712.7(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006997""(nucleus organization)|go:""GO:0019216""(regulation of lipid metabolic process)|interpro:IPR026139|mint:Q8NBJ4|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_057632.2|refseq:NP_808800.1|panther:PTHR15896(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FwRCscVoC13GphL6UBpJVsxENgE1392	rogid:UTZSkGqBWSsT8rAOnkCcFHD8+EU9606	intact-crc:042C94A815A69958|rigid:fuN0v/O8y4DOwCLvgJK0Z86kCyc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A6NH11	uniprotkb:A0A6L8PKS7	intact:EBI-2833102|ensembl:ENSP00000328070.7|uniprotkb:A7E2T2	intact:EBI-2809705|uniprotkb:Q6HR58|uniprotkb:Q6KKH5|uniprotkb:E9QWF2|uniprotkb:E9QWF3|uniprotkb:A0A2P0HL14|uniprotkb:Q81XC3	psi-mi:gltd2_human(display_long)|uniprotkb:GLTPD2(gene name)|psi-mi:GLTPD2(display_short)	psi-mi:a0a6l8pks7_bacan(display_long)|uniprotkb:GBAA_5317(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833099|imex:IM-13779-3723	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000182327.8(gene)|ensembl:ENST00000331264.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0035627""(ceramide transport)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:1902387""(ceramide 1-phosphate binding)|go:""GO:1902388""(ceramide 1-phosphate transfer activity)|interpro:IPR014830(Glycolipid transfer protein, GLTP)|interpro:IPR036497|panther:PTHR10219(orthology-group)"	"interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR051310|interpro:IPR025278|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|refseq:WP_000455036.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qrtAo6iynvi9V3yWkhI1GBMaXXk9606	rogid:LEAQuRzrOsJwYgZq7QXDmoKrfqM1392	intact-crc:9E4B239EABD267B6|rigid:OqwsnMKSlDzBF+rDxNjAADTBB8M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94925	uniprotkb:A0A6L8PSZ0	intact:EBI-1043737|uniprotkb:Q9UL05|uniprotkb:Q9UL06|uniprotkb:Q9UL07|uniprotkb:Q9UN40|ensembl:ENSP00000317379.3	intact:EBI-2820328|uniprotkb:Q6KVK0|uniprotkb:Q6I1Q8|uniprotkb:E9QX09|uniprotkb:E9QX10|uniprotkb:Q81TH5|uniprotkb:A0A0F7RLZ4	psi-mi:glsk_human(display_long)|uniprotkb:GLS(gene name)|psi-mi:GLS(display_short)|uniprotkb:GLS1(gene name synonym)|uniprotkb:KIAA0838(gene name synonym)|uniprotkb:L-glutamine amidohydrolase(gene name synonym)|uniprotkb:K-glutaminase(gene name synonym)	psi-mi:a0a6l8psz0_bacan(display_long)|uniprotkb:GBAA_1300(locus name)|uniprotkb:potD(gene name)|psi-mi:potD(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833111|imex:IM-13779-3721	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115419.14(gene)|ensembl:ENST00000320717.8(transcript)|go:""GO:0001967""(suckling behavior)|go:""GO:0002087""(regulation of respiratory gaseous exchange by nervous system process)|go:""GO:0004359""(glutaminase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006543""(glutamine catabolic process)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0045202""(synapse)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0090461""(intracellular glutamate homeostasis)|interpro:IPR002110(Ankyrin)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR036770|interpro:IPR041541|mint:O94925|rcsb pdb:3CZD|rcsb pdb:3UNW|rcsb pdb:3UO9|rcsb pdb:3VOY|rcsb pdb:3VOZ|rcsb pdb:3VP0|rcsb pdb:3VP1|rcsb pdb:3VP2|rcsb pdb:3VP3|rcsb pdb:3VP4|rcsb pdb:4O7D|rcsb pdb:5D3O|rcsb pdb:5FI2|rcsb pdb:5FI6|rcsb pdb:5FI7|rcsb pdb:5HL1|rcsb pdb:5I94|rcsb pdb:5JYO|rcsb pdb:5JYP|rcsb pdb:5U0I|rcsb pdb:5U0J|rcsb pdb:5UQE|rcsb pdb:5WJ6|rcsb pdb:6LOX|rcsb pdb:6UJG|rcsb pdb:6UJM|rcsb pdb:6UK6|rcsb pdb:6UKB|rcsb pdb:6UL9|rcsb pdb:6ULA|rcsb pdb:6ULJ|rcsb pdb:6UMC|rcsb pdb:6UMD|rcsb pdb:6UME|rcsb pdb:6UMF|rcsb pdb:7REN|rcsb pdb:7RGG|rcsb pdb:7SBM|rcsb pdb:7SBN|rcsb pdb:8BSK|rcsb pdb:8BSL|rcsb pdb:8BSM|rcsb pdb:8BSN|rcsb pdb:8GWR|rcsb pdb:8IMA|rcsb pdb:8IMB|rcsb pdb:8JUB|rcsb pdb:8JUE|rcsb pdb:8SZJ|reactome:R-HSA-210500|reactome:R-HSA-5628897|reactome:R-HSA-8964539|refseq:NP_001243239.1|refseq:NP_055720.3|efo:""Orphanet:557056""|efo:""Orphanet:557064""|dip:DIP-50591N|panther:PTHR12544(orthology-group)"	"interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|go:""GO:0015846""(polyamine transport)|go:""GO:0019808""(polyamine binding)|go:""GO:0042597""(periplasmic space)|refseq:WP_000779003.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:IV2jY1Qj63eTVPmTndDavjoUM2w9606	rogid:N5S8foUwPHnwNk6wOSAsTNvMzIc1392	intact-crc:9B6ED487898C6C17|rigid:n52k6n/ztHNgFDEtDotG+1D3oHk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48060	uniprotkb:A0A6L8PT45	intact:EBI-2833130|ensembl:ENSP00000266659.3|uniprotkb:Q969K2|uniprotkb:Q15409|uniprotkb:A7YET6|uniprotkb:F8VUC2	intact:EBI-2825742|uniprotkb:Q6KVF1|uniprotkb:Q6I1K2|uniprotkb:E9RAT2|uniprotkb:E9RAT3|uniprotkb:Q81TC5|uniprotkb:A0A0J1HZ85	psi-mi:glip1_human(display_long)|uniprotkb:GLIPR1(gene name)|psi-mi:GLIPR1(display_short)|uniprotkb:GLIPR(gene name synonym)|uniprotkb:RTVP1(gene name synonym)|uniprotkb:Protein RTVP-1(gene name synonym)	psi-mi:a0a6l8pt45_bacan(display_long)|uniprotkb:queE(gene name)|psi-mi:queE(display_short)|uniprotkb:Queuosine biosynthesis protein QueE(gene name synonym)|uniprotkb:GBAA_1361(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833136|imex:IM-13779-3724	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000139278.10(gene)|ensembl:ENST00000266659.8(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0035577""(azurophil granule membrane)|interpro:IPR001283(Allergen V5/Tpx-1 related)|interpro:IPR002413(Ves allergen)|interpro:IPR014044(SCP-like extracellular)|interpro:IPR018244|interpro:IPR034121|interpro:IPR035940|mint:P48060|rcsb pdb:3Q2R|rcsb pdb:3Q2U|reactome:R-HSA-1989781|reactome:R-HSA-6798695|refseq:NP_006842.2|panther:PTHR10334(orthology-group)"	"interpro:IPR017742(""7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE"")|interpro:IPR007197(Radical SAM)|interpro:IPR024924|go:""GO:0000287""(magnesium ion binding)|go:""GO:0008616""(queuosine biosynthetic process)|go:""GO:0016840""(carbon-nitrogen lyase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:1904047""(S-adenosyl-L-methionine binding)|refseq:WP_000036288.1|interpro:IPR013785(Aldolase-type TIM barrel)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2yhZ5byCradyh/gvOmNzNM7SqiI9606	rogid:gTku1wUCCSbVrsy9wG9sItVGxNc1392	intact-crc:1678A623AB7DCF86|rigid:e6UoULxrrrWYxiD+tM3ix4QH8+M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15104	uniprotkb:A0A2P0HKX3	intact:EBI-746653|ensembl:ENSP00000307900.5|ensembl:ENSP00000344958.5|ensembl:ENSP00000356537.6|ensembl:ENSP00000398320.2|uniprotkb:Q499Y9|uniprotkb:Q5T9Z1|uniprotkb:Q7Z3W4|uniprotkb:Q8IZ17	intact:EBI-2833118|uniprotkb:Q6KKK5|uniprotkb:E9RBR3|uniprotkb:Q81XF5	psi-mi:glna_human(display_long)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:GLUL(gene name)|psi-mi:GLUL(display_short)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Palmitoyltransferase GLUL(gene name synonym)	psi-mi:a0a2p0hkx3_bacan(display_long)|uniprotkb:nprB(gene name)|psi-mi:nprB(display_short)|uniprotkb:GBAA_5282(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833123|imex:IM-13779-3722	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000135821.20(gene)|ensembl:ENST00000311223.9(transcript)|ensembl:ENST00000331872.11(transcript)|ensembl:ENST00000339526.9(transcript)|ensembl:ENST00000417584.6(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0004356""(glutamine synthetase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006538""(glutamate catabolic process)|go:""GO:0006542""(glutamine biosynthetic process)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009749""(response to glucose)|go:""GO:0010594""(regulation of endothelial cell migration)|go:""GO:0018345""(protein palmitoylation)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0042254""(ribosome biogenesis)|go:""GO:0042802""(identical protein binding)|go:""GO:0044297""(cell body)|go:""GO:0046872""(metal ion binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097386""(glial cell projection)|go:""GO:1903670""(regulation of sprouting angiogenesis)|go:""GO:1904749""(regulation of protein localization to nucleolus)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|interpro:IPR050292|mint:P15104|rcsb pdb:2OJW|rcsb pdb:2QC8|rcsb pdb:7EVT|rcsb pdb:8DNU|reactome:R-HSA-210455|reactome:R-HSA-8964539|refseq:NP_001028216.1|refseq:NP_001028228.1|refseq:NP_002056.2|refseq:XP_006711341.1|efo:""Orphanet:71278""|dip:DIP-308N|panther:PTHR20852(orthology-group)"	"go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|interpro:IPR023612|interpro:IPR001570(Peptidase M4, thermolysin C-terminal)|interpro:IPR013856(Peptidase M4, thermolysin)|interpro:IPR011096(Propeptide, peptidase M4 and M36)|interpro:IPR025711|refseq:WP_000745139.1|interpro:IPR027268|interpro:IPR050728"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/22	rogid:UOOgfw1g+kmpsEx64pUbW9GfmYw9606	rogid:jDrNsbAmLjCcS5w+4qyhfL0zKfQ1392	intact-crc:9B7DEF5E0A3985E9|rigid:t4mrzvU5GzXWv6w9qxUHRtRu6uk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PT07	uniprotkb:Q8TEQ6	intact:EBI-2833187|uniprotkb:Q6KVC9|uniprotkb:Q6I1H8|uniprotkb:E9RDM0|uniprotkb:E9RDM1|uniprotkb:A0A2P0HBK8|uniprotkb:Q81TA1	intact:EBI-443630|ensembl:ENSP00000285873.6|uniprotkb:Q14CV0|uniprotkb:Q8WWV4|uniprotkb:Q969W4|uniprotkb:Q9H9K3|uniprotkb:Q9UFI5	psi-mi:a0a6l8pt07_bacan(display_long)|uniprotkb:Propionate 3-nitronate monooxygenase(gene name synonym)|uniprotkb:GBAA_1385(locus name)	psi-mi:gemi5_human(display_long)|uniprotkb:GEMIN5(gene name)|psi-mi:GEMIN5(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833184|imex:IM-13779-3730	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0009636""(response to toxic substance)|go:""GO:0018580""(nitronate monooxygenase activity)|go:""GO:0051213""(dioxygenase activity)|interpro:IPR004136(2-nitropropane dioxygenase, NPD)|interpro:IPR013785(Aldolase-type TIM barrel)|refseq:WP_000495265.1"	"ensembl:ENSG00000082516.9(gene)|ensembl:ENST00000285873.8(transcript)|go:""GO:0000340""(RNA 7-methylguanosine cap binding)|go:""GO:0000387""(spliceosomal snRNP assembly)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006412""(translation)|go:""GO:0006417""(regulation of translation)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0017069""(snRNA binding)|go:""GO:0030619""(U1 snRNA binding)|go:""GO:0030621""(U4 snRNA binding)|go:""GO:0030622""(U4atac snRNA binding)|go:""GO:0032797""(SMN complex)|go:""GO:0034718""(SMN-Gemin2 complex)|go:""GO:0034719""(SMN-Sm protein complex)|go:""GO:0043022""(ribosome binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0097504""(Gemini of Cajal bodies)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|interpro:IPR052640|mint:Q8TEQ6|rcsb pdb:5GXH|rcsb pdb:5GXI|rcsb pdb:5H1J|rcsb pdb:5H1K|rcsb pdb:5H1L|rcsb pdb:5H1M|rcsb pdb:5H3S|rcsb pdb:5H3T|rcsb pdb:5H3U|rcsb pdb:5TEE|rcsb pdb:5TEF|rcsb pdb:5THA|rcsb pdb:6RNQ|rcsb pdb:6RNS|rcsb pdb:7XDT|rcsb pdb:7XGR|reactome:R-HSA-191859|reactome:R-HSA-9754678|refseq:NP_001239085.1|refseq:NP_056280.2|efo:""Orphanet:88616""|panther:PTHR46362(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/8C3fIFZMIAHN/Ap+GUA6PY4Bkk1392	rogid:9D6k6KGv+klNdYzgQClnthCYJuo9606	intact-crc:705922B5A6C4809F|rigid:ndy8ZEDeu5n6JnAPvF9oCrkNz24	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TF65	uniprotkb:A0A6L7HJD9	intact:EBI-712067|uniprotkb:Q8IYD3|uniprotkb:Q9NXS7|ensembl:ENSP00000359795.3	intact:EBI-2818003|uniprotkb:Q6KS63|uniprotkb:Q6HY50|uniprotkb:E9R233|uniprotkb:E9R234|uniprotkb:Q81PX9|uniprotkb:A0A0F7RI73	psi-mi:gipc2_human(display_long)|uniprotkb:GIPC2(gene name)|psi-mi:GIPC2(display_short)	psi-mi:a0a6l7hjd9_bacan(display_long)|uniprotkb:GBAA_2661(locus name)|uniprotkb:adP1(gene name)|psi-mi:adP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833157|imex:IM-13779-3729	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137960.6(gene)|ensembl:ENST00000370759.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|mint:Q8TF65|rcsb pdb:3GGE|refseq:NP_060125.4|refseq:NP_001291654.1|panther:PTHR12259(orthology-group)"	interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|refseq:WP_000845176.1|interpro:IPR050491	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tmXszDsKNzUfki6x7swoLDtaow89606	rogid:3qobiBGRawBE8K1XIyLVSFvnDtE1392	intact-crc:D2C0F4DD299C2942|rigid:Rvd02NPf3J1Jy5opc3+xzmnAZMo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81L31	uniprotkb:Q8TF65	intact:EBI-2833171|uniprotkb:Q6KLT1|uniprotkb:Q6HSI6	intact:EBI-712067|uniprotkb:Q8IYD3|uniprotkb:Q9NXS7|ensembl:ENSP00000359795.3	psi-mi:syfb_bacan(display_long)|uniprotkb:pheT(gene name)|psi-mi:pheT(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:BAS4455(locus name)|uniprotkb:BA_4803(locus name)|uniprotkb:GBAA_4803(locus name)	psi-mi:gipc2_human(display_long)|uniprotkb:GIPC2(gene name)|psi-mi:GIPC2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833177|imex:IM-13779-3727	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004826""(phenylalanine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006432""(phenylalanyl-tRNA aminoacylation)|go:""GO:0009328""(phenylalanine-tRNA ligase complex)|go:""GO:0016740""(transferase activity)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR009061(Putative DNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004532(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial)|interpro:IPR020825|interpro:IPR005121(Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR033714|refseq:WP_000498183.1|interpro:IPR036690|interpro:IPR041616|refseq:NP_847006.1|refseq:YP_030702.1|interpro:IPR045060|interpro:IPR045864"	"ensembl:ENSG00000137960.6(gene)|ensembl:ENST00000370759.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|mint:Q8TF65|rcsb pdb:3GGE|refseq:NP_060125.4|refseq:NP_001291654.1|panther:PTHR12259(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:URiR9EbysKGMwhPbhGylTT9ISSI1392	rogid:tmXszDsKNzUfki6x7swoLDtaow89606	intact-crc:329E3D4D52663C34|rigid:ieqeTd9WaVNNB9XM4aDeszz6X/A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TF65	uniprotkb:Q81ZE7	intact:EBI-712067|uniprotkb:Q8IYD3|uniprotkb:Q9NXS7|ensembl:ENSP00000359795.3	intact:EBI-2814801|uniprotkb:Q6I493|uniprotkb:Q6KXZ9	psi-mi:gipc2_human(display_long)|uniprotkb:GIPC2(gene name)|psi-mi:GIPC2(display_short)	psi-mi:gatb_bacan(display_long)|uniprotkb:gatB(gene name)|psi-mi:gatB(display_short)|uniprotkb:BA_0322(locus name)|uniprotkb:GBAA_0322(locus name)|uniprotkb:BAS0307(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833164|imex:IM-13779-3726	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137960.6(gene)|ensembl:ENST00000370759.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|mint:Q8TF65|rcsb pdb:3GGE|refseq:NP_060125.4|refseq:NP_001291654.1|panther:PTHR12259(orthology-group)"	"interpro:IPR017959|interpro:IPR006075(GatB N-terminal region)|interpro:IPR018027|interpro:IPR003789(GatB/Yqey)|interpro:IPR004413(""Glutamyl-tRNA(Gln) amidotransferase B subunit"")|interpro:IPR017958|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0050566""(""asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0050567""(""glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"")|go:""GO:0070681""(glutaminyl-tRNAGln biosynthesis via transamidation)|refseq:WP_001047678.1|interpro:IPR023168|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR042114|refseq:NP_842869.1|refseq:YP_026587.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tmXszDsKNzUfki6x7swoLDtaow89606	rogid:hWBgI8hoc7BXz5vPZa3WyZ167T41392	intact-crc:3FF00B4D53BF010C|rigid:1O4OQ4fKPzqdEysTPIS/2bX9DC4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PDF7	uniprotkb:Q9Y2X7	intact:EBI-2810594|uniprotkb:Q6KW06|uniprotkb:Q6I272|uniprotkb:E9QVC8|uniprotkb:E9QVC9|uniprotkb:Q81TY6|uniprotkb:A0A0F7RMC5	intact:EBI-466061|uniprotkb:Q86SS0|uniprotkb:Q9BRJ4|uniprotkb:B4DSV3|uniprotkb:B4DGU9|ensembl:ENSP00000225394.3	psi-mi:a0a6l8pdf7_bacan(display_long)|uniprotkb:GBAA_1114(locus name)	psi-mi:git1_human(display_long)|uniprotkb:GIT1(gene name)|psi-mi:GIT1(display_short)|uniprotkb:G protein-coupled receptor kinase-interactor 1(gene name synonym)|uniprotkb:GRK-interacting protein 1(gene name synonym)|uniprotkb:Cool-associated and tyrosine-phosphorylated protein 1(gene name synonym)|uniprotkb:p95-APP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833143|imex:IM-13779-3728	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029441|interpro:IPR010499(Bacterial transcription activator, effector binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018062|interpro:IPR018060|interpro:IPR011256(Regulatory factor, effector, bacterial)|interpro:IPR020449|interpro:IPR053182|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0043565""(sequence-specific DNA binding)|refseq:WP_000446832.1"	"refseq:NP_001078923.1|refseq:NP_054749.2|ensembl:ENSG00000108262.16(gene)|ensembl:ENST00000225394.8(transcript)|go:""GO:0001957""(intramembranous ossification)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007420""(brain development)|go:""GO:0007626""(locomotory behavior)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0030027""(lamellipodium)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032012""(regulation of ARF protein signal transduction)|go:""GO:0032465""(regulation of cytokinesis)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0036465""(synaptic vesicle recycling)|go:""GO:0043005""(neuron projection)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0044305""(calyx of Held)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045202""(synapse)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0045820""(negative regulation of glycolytic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0048013""(ephrin receptor signaling pathway)|go:""GO:0048666""(neuron development)|go:""GO:0061743""(motor learning)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0090063""(positive regulation of microtubule nucleation)|go:""GO:0097431""(mitotic spindle pole)|go:""GO:0098794""(postsynapse)|go:""GO:0099171""(presynaptic modulation of chemical synaptic transmission)|go:""GO:0106015""(negative regulation of inflammatory response to wounding)|go:""GO:2000300""(regulation of synaptic vesicle exocytosis)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724(""Spa2 homology (SHD) of GIT"")|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|interpro:IPR047161|mint:Q9Y2X7|reactome:R-HSA-3928664|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9619229|panther:PTHR46097(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JhKSQU+Dy6soIOR2a8KdT3BUrsA1392	rogid:9POm+EVvD4/BQh6bApnpXCAZyZo9606	intact-crc:DEBA55CEED23A77A|rigid:Q5dzA5WNpqOartLKHgeWGmTbH+E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8TF65	uniprotkb:A0A6L8PL93	intact:EBI-712067|uniprotkb:Q8IYD3|uniprotkb:Q9NXS7|ensembl:ENSP00000359795.3	intact:EBI-2812142|uniprotkb:Q6HXW8|uniprotkb:Q6KRZ0|uniprotkb:E9R374|uniprotkb:E9R375|uniprotkb:Q81PQ4|uniprotkb:A0A0F7RGT7	psi-mi:gipc2_human(display_long)|uniprotkb:GIPC2(gene name)|psi-mi:GIPC2(display_short)	psi-mi:a0a6l8pl93_bacan(display_long)|uniprotkb:ypeB(gene name)|psi-mi:ypeB(display_short)|uniprotkb:GBAA_2747(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833150|imex:IM-13779-3725	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000137960.6(gene)|ensembl:ENST00000370759.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0042802""(identical protein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|mint:Q8TF65|rcsb pdb:3GGE|refseq:NP_060125.4|refseq:NP_001291654.1|panther:PTHR12259(orthology-group)"	"interpro:IPR014239(Spore germination YpeB)|go:""GO:0009847""(spore germination)|refseq:WP_000943708.1|interpro:IPR025711|interpro:IPR048402"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tmXszDsKNzUfki6x7swoLDtaow89606	rogid:ArcU2AZZMp9ttGHYayHY+K9lpzU1392	intact-crc:CEB5BBCEE4CD580A|rigid:byrNkNi/h95+kNSglaHQ6Bgy0+8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06396	uniprotkb:A0A6L8Q050	intact:EBI-351506|uniprotkb:Q8WVV7|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8|ensembl:ENSP00000362924.4	intact:EBI-2812424|uniprotkb:Q6HS63|uniprotkb:Q6F089|uniprotkb:E9RAL4|uniprotkb:E9RAL5|uniprotkb:Q81KQ7|uniprotkb:A0A0F7RCB3	psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym)	psi-mi:a0a6l8q050_bacan(display_long)|uniprotkb:GBAA_4933(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833196|imex:IM-13779-3735	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:85448""|ensembl:ENSG00000148180.22(gene)|ensembl:ENST00000373818.8(transcript)|go:""GO:0002102""(podosome)|go:""GO:0003779""(actin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0007015""(actin filament organization)|go:""GO:0007417""(central nervous system development)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014891""(striated muscle atrophy)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016528""(sarcoplasm)|go:""GO:0030027""(lamellipodium)|go:""GO:0030031""(cell projection assembly)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030478""(actin cap)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0031648""(protein destabilization)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035994""(response to muscle stretch)|go:""GO:0036313""(phosphatidylinositol 3-kinase catalytic subunit binding)|go:""GO:0042989""(obsolete sequestering of actin monomers)|go:""GO:0045159""(myosin II binding)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0051014""(actin filament severing)|go:""GO:0051015""(actin filament binding)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051127""(positive regulation of actin nucleation)|go:""GO:0051693""(actin filament capping)|go:""GO:0055119""(relaxation of cardiac muscle)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071801""(regulation of podosome assembly)|go:""GO:0072562""(blood microparticle)|go:""GO:0086003""(cardiac muscle cell contraction)|go:""GO:0097017""(renal protein absorption)|go:""GO:0097284""(hepatocyte apoptotic process)|go:""GO:1902174""(positive regulation of keratinocyte apoptotic process)|go:""GO:1903903""(regulation of establishment of T cell polarity)|go:""GO:1903906""(regulation of plasma membrane raft polarization)|go:""GO:1903909""(regulation of receptor clustering)|go:""GO:1903923""(positive regulation of protein processing in phagocytic vesicle)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990000""(amyloid fibril formation)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1P8Z|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:6QW3|rcsb pdb:7P2B|rcsb pdb:8VIZ|rcsb pdb:8VKH|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121135.2|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_937895.1|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N|panther:PTHR11977(orthology-group)"	"interpro:IPR035097|interpro:IPR000787(Peptidase M29, aminopeptidase II)|interpro:IPR052170|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_000654736.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606	rogid:Ca6ZxzgWZSbnRiXpfkXmNm3rVl01392	intact-crc:EB29F01A2F19B4BB|rigid:RmRBDaVxPMuM+UbJimhtaX4Az5g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HAB1	uniprotkb:Q9HCC8	intact:EBI-2822370|uniprotkb:Q6I0A8|uniprotkb:Q6KU81|uniprotkb:E9QSH5|uniprotkb:E9QSH6|uniprotkb:Q81S29|uniprotkb:A0A0J1I1X8	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	psi-mi:a0a6l7hab1_bacan(display_long)|uniprotkb:GBAA_1849(locus name)|uniprotkb:ilvE2(gene name)|psi-mi:ilvE2(display_short)|uniprotkb:ilvE(gene name synonym)	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833227|imex:IM-13779-3732	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR018300|interpro:IPR005785(Branched-chain amino acid aminotransferase I)|refseq:WP_000528132.1|go:""GO:0004084""(branched-chain-amino-acid transaminase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009098""(L-leucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|interpro:IPR036038|interpro:IPR050571|interpro:IPR043131|interpro:IPR043132"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CdDThaf3cLzDxzQA4Zeyb4X/YMk1392	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	intact-crc:59BBF1B9B84C6795|rigid:EW8+M+/+IXW2YzR5HlS9uwlGFdQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WTR4	uniprotkb:Q81WF2	intact:EBI-2833203|ensembl:ENSP00000337972.3|ensembl:ENSP00000433214.1|uniprotkb:Q49AQ5|uniprotkb:Q8N781|uniprotkb:Q6UX76|uniprotkb:Q8TB77|uniprotkb:Q7Z4S0|uniprotkb:Q8NCB7	intact:EBI-2817282|uniprotkb:Q6KNT5|uniprotkb:Q6HUK0	psi-mi:gdpd5_human(display_long)|uniprotkb:GDPD5(gene name)|psi-mi:GDPD5(display_short)|uniprotkb:GDE2(gene name synonym)|uniprotkb:Glycerophosphodiester phosphodiesterase 2(gene name synonym)|uniprotkb:Glycerophosphocholine phosphodiesterase GDPD5(gene name synonym)|uniprotkb:Phosphoinositide phospholipase C GDPD5(gene name synonym)|uniprotkb:PP6037(orf name)|uniprotkb:PP9363(orf name)|uniprotkb:UNQ1850/PRO3580(orf name)	psi-mi:carb_bacan(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:BAS3737(locus name)|uniprotkb:BA_4025(locus name)|uniprotkb:GBAA_4025(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833213|imex:IM-13779-3731	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000158555.15(gene)|ensembl:ENST00000336898.8(transcript)|ensembl:ENST00000529721.5(transcript)|go:""GO:0004435""(phosphatidylinositol-4,5-bisphosphate phospholipase C activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007399""(nervous system development)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0012505""(endomembrane system)|go:""GO:0030426""(growth cone)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0047389""(glycerophosphocholine phosphodiesterase activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR017946|interpro:IPR030395|reactome:R-HSA-6814848|refseq:XP_011543587.1|refseq:XP_011543589.1|refseq:NP_110419.5|refseq:XP_006718760.1|panther:PTHR23344(orthology-group)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_001126118.1|interpro:IPR033937|interpro:IPR036897|interpro:IPR036914|refseq:NP_846266.1|refseq:YP_029988.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+8jGx1m8fzBQZNg5hp+3XOnfp+A9606	rogid:FyFaDJJLB3UEDCKeq5/d+MJMrUc1392	intact-crc:008F9A2FCB035DC9|rigid:IKlKKlfYqtY/4nBxHOyGabI8PGE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PW84	uniprotkb:Q9HCC8	intact:EBI-2810036|uniprotkb:Q6I0D7|uniprotkb:Q6KUA7|uniprotkb:E9QSG5|uniprotkb:E9QSG6|uniprotkb:Q81S56|uniprotkb:A0A0F7RJG7	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	psi-mi:a0a6l8pw84_bacan(display_long)|uniprotkb:GBAA_1818(locus name)	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833220|imex:IM-13779-3734	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002901(Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase)|interpro:IPR001119(S-layer homology region)|refseq:WP_000756001.1|interpro:IPR051465|go:""GO:0004040""(amidase activity)|go:""GO:0030115""(S-layer)"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rvtlwru3355qXbTQawe6Hx/9UN01392	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	intact-crc:A706A46A04ACD534|rigid:QSAt5+3pCiGwWZQ++QzcFO7WF94	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCC8	uniprotkb:Q81WE9	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	intact:EBI-2810609|uniprotkb:Q6HUJ7|uniprotkb:Q6KNT2	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	psi-mi:pyrb_bacan(display_long)|uniprotkb:pyrB(gene name)|psi-mi:pyrB(display_short)|uniprotkb:Aspartate transcarbamylase(gene name synonym)|uniprotkb:BA_4028(locus name)|uniprotkb:GBAA_4028(locus name)|uniprotkb:BAS3740(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833234|imex:IM-13779-3733	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|go:""GO:0004070""(aspartate carbamoyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0016597""(amino acid binding)|go:""GO:0044205""('de novo' UMP biosynthetic process)|refseq:WP_000018849.1|interpro:IPR036901|refseq:NP_846269.1|refseq:YP_029991.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	rogid:kYGPh/0/j5j2yg9ZpemwC1fkeWw1392	intact-crc:9328A24839C85AF8|rigid:qyEr01/2sX2y1wE24HZZKlnbNY0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCC8	uniprotkb:A0A6L8P8Y4	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	intact:EBI-2833265|uniprotkb:Q6KKR8|uniprotkb:Q6HRE8|uniprotkb:E9QZJ1|uniprotkb:E9QZJ2|uniprotkb:Q81XM1|uniprotkb:A0A0F7RBD2	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	psi-mi:a0a6l8p8y4_bacan(display_long)|uniprotkb:sufB(gene name)|psi-mi:sufB(display_short)|uniprotkb:GBAA_5213(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833271|imex:IM-13779-3737	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"go:""GO:0016226""(iron-sulfur cluster assembly)|interpro:IPR010231(SUF system FeS cluster assembly, SufB)|interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|refseq:WP_001118828.1|interpro:IPR037284|interpro:IPR045595"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	rogid:R1FZEpOmPuYXYij0YfnD1QQwFTY1392	intact-crc:4B066B49DBC066F8|rigid:eBGqJdcgfNs3H70Ab+5amWrRvRU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PJN2	uniprotkb:Q9HCC8	intact:EBI-2833256|uniprotkb:Q6KPX7|uniprotkb:Q6HVR0|uniprotkb:E9QWW8|uniprotkb:E9QWW9|uniprotkb:Q81YG7|uniprotkb:A0A0F7REF4	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	psi-mi:a0a6l8pjn2_bacan(display_long)|uniprotkb:GBAA_3582(locus name)	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833253|imex:IM-13779-3739	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0008757""(S-adenosylmethionine-dependent methyltransferase activity)|go:""GO:0016757""(glycosyltransferase activity)|interpro:IPR029044|interpro:IPR029063|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR013216(Methyltransferase type 11)|refseq:WP_000064845.1"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8/KEsRBORD3CZhPde3Unv2VmyvU1392	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	intact-crc:67FCEEBBFC75F57F|rigid:xrw3tG9ujYRflDk/+mC9bq4o30Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AL29	uniprotkb:Q9HCC8	intact:EBI-2815022|uniprotkb:Q6KP86|uniprotkb:Q6HV12|uniprotkb:E9QUK5|uniprotkb:E9QUK6|uniprotkb:Q81WV8|uniprotkb:A0A0J1I450	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	psi-mi:a0a6h3al29_bacan(display_long)|uniprotkb:GBAA_3857(locus name)	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833278|imex:IM-13779-3738	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000292(Formate/nitrite transporter)|interpro:IPR024002|interpro:IPR023271|go:""GO:0005886""(plasma membrane)|go:""GO:0015499""(formate transmembrane transporter activity)|refseq:WP_000110521.1"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9zuhNcbWkPnfpCTp+1paFSJCwEY1392	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	intact-crc:C73323EADDCF31C9|rigid:lxCCF/p+RPYA0lZ+RpS8DEJs0QY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCC8	uniprotkb:A0A6L8P2Z7	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	intact:EBI-2833285|uniprotkb:Q6I4U3|uniprotkb:Q6KYI8|uniprotkb:E9RBC9|uniprotkb:E9RBD0|uniprotkb:Q81VT9|uniprotkb:A0A0F7R9K2	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	psi-mi:a0a6l8p2z7_bacan(display_long)|uniprotkb:GBAA_0101(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833290|imex:IM-13779-3740	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"go:""GO:0008757""(S-adenosylmethionine-dependent methyltransferase activity)|go:""GO:0032259""(methylation)|interpro:IPR029063|interpro:IPR007848(Methyltransferase small)|refseq:WP_000763286.1|interpro:IPR046977"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	rogid:9gWyCvYBIid5Xd4jNbUfJiBb6F01392	intact-crc:04B675A5B3A46A42|rigid:SF9npbFsaBOTQhToNHOsnvzd3GQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PQF7	uniprotkb:Q9HCC8	intact:EBI-2833244|uniprotkb:Q6I430|uniprotkb:Q6KXU0|uniprotkb:E9R0E3|uniprotkb:E9R0E4|uniprotkb:Q81Z88|uniprotkb:A0A0F7RI18	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	psi-mi:a0a6l8pqf7_bacan(display_long)|uniprotkb:GBAA_0384(locus name)	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833241|imex:IM-13779-3736	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_000025955.1|interpro:IPR032781|interpro:IPR051309"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gXKAvORMuAleC8p8fxN29CGaZbg1392	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	intact-crc:5E1EC9869C78996A|rigid:8WVDG7NhrYTbLVNvu5Hb+cyzK5k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7GZR7	uniprotkb:Q9HCC8	intact:EBI-2811037|uniprotkb:Q6HT99|uniprotkb:E9R942|uniprotkb:A0A0F7R886|uniprotkb:Q6KMJ2	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	psi-mi:a0a6l7gzr7_bacan(display_long)|uniprotkb:GBAA_4512(locus name)	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833318|imex:IM-13779-3744	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017221(Uncharacterised conserved protein UPF0135, NIF3)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|refseq:WP_000036216.1|interpro:IPR015867(Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal)|interpro:IPR036069"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QLw+C4toLL3VxZPIV6og9r1Ib9U1392	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	intact-crc:266DDD3D236C4D3F|rigid:XW2Zln75/WtoczWOuF8jxPgDSCA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1W4U6	uniprotkb:Q9HCC8	intact:EBI-2814531|uniprotkb:Q6KTH8|uniprotkb:Q6HZI8|uniprotkb:E9QZ61|uniprotkb:E9QZ62|uniprotkb:Q81RB5|uniprotkb:A0A0F7RF35	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	psi-mi:a0a4y1w4u6_bacan(display_long)|uniprotkb:GBAA_2135(locus name)|uniprotkb:moeA1(gene name)|psi-mi:moeA1(display_short)	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833304|imex:IM-13779-3741	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005111(MoeA, C-terminal, domain IV)|interpro:IPR005110(MoeA, N-terminal, domain I and II)|interpro:IPR001453(Molybdopterin binding)|interpro:IPR038987|go:""GO:0005829""(cytosol)|go:""GO:0006777""(Mo-molybdopterin cofactor biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0061599""(molybdopterin molybdotransferase activity)|interpro:IPR036135|interpro:IPR036425|interpro:IPR036688|refseq:WP_000880220.1"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:r8E0EfyfJU7lnseaLwPX1Eah4wo1392	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	intact-crc:FB42535FB1DBF99B|rigid:Cgnkhbl+7yPw7o3IEf5z8ciy8Fw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCC8	uniprotkb:A0A6L8P0C4	intact:EBI-717037|intact:EBI-2833321|uniprotkb:Q9NXJ6|uniprotkb:B4DRH4|uniprotkb:B4DVC9|ensembl:ENSP00000363503.3	intact:EBI-2815855|uniprotkb:Q6I4K7|uniprotkb:Q6KYA9|uniprotkb:E9R7J1|uniprotkb:E9R7J2|uniprotkb:Q81VL0|uniprotkb:A0A0F7R444	psi-mi:gdpd2_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase 3(gene name synonym)|uniprotkb:Osteoblast differentiation promoting factor(gene name synonym)|uniprotkb:GDPD2(gene name)|psi-mi:GDPD2(display_short)|uniprotkb:GDE3(gene name synonym)|uniprotkb:OBDPF(gene name synonym)|uniprotkb:UNQ1935/PRO4418(orf name)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 2(gene name synonym)	psi-mi:a0a6l8p0c4_bacan(display_long)|uniprotkb:GBAA_0187(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833297|imex:IM-13779-3743	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060181.2|refseq:NP_001164662.1|refseq:NP_001164663.1|refseq:NP_001164664.1|ensembl:ENSG00000130055.14(gene)|ensembl:ENST00000374382.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0047394""(glycerophosphoinositol inositolphosphodiesterase activity)|interpro:IPR017946|interpro:IPR030395|mint:Q9HCC8|panther:PTHR23344(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013563(Oligopeptide/dipeptide ABC transporter, C-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0015833""(peptide transport)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR050388|refseq:WP_000079890.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BjIbEnVrHaAIXmqxwj9fyTesa5s9606	rogid:zFdErf7S8j94bS32fOw888UADuE1392	intact-crc:6C2863C6E1F569C4|rigid:QXqA6L6KFns1S+1eQArWeV2yDnM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50395	uniprotkb:A0A6H3AJ28	intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|uniprotkb:Q5SX88|ensembl:ENSP00000369538.4	intact:EBI-2829167|uniprotkb:Q6KLI1|uniprotkb:E9R738|uniprotkb:Q81KS6|uniprotkb:A0A2B0Y418	psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym)	psi-mi:a0a6h3aj28_bacan(display_long)|uniprotkb:GBAA_4914(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833311|imex:IM-13779-3742	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001108628.1|refseq:NP_001485.2|dip:DIP-50593N|ensembl:ENSG00000057608.18(gene)|ensembl:ENST00000380191.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005093""(Rab GDP-dissociation inhibitor activity)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031982""(vesicle)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035578""(azurophil granule lumen)|go:""GO:0045202""(synapse)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902018""(negative regulation of cilium assembly)|go:""GO:1903565""(negative regulation of protein localization to cilium)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|panther:PTHR11787(orthology-group)"	"go:""GO:0016020""(membrane)|refseq:WP_000066437.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606	rogid:OOwQ0R71r0h8mgM52F5enp82wDk1392	intact-crc:09C3CDD5BE6ABB5A|rigid:dXQj7thr2/GzbcYCe8schf9YGwU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NZC3	uniprotkb:Q81TU9	intact:EBI-2833330|ensembl:ENSP00000261386.3|uniprotkb:Q7KYR4|uniprotkb:O43334|uniprotkb:Q6PKF7	intact:EBI-2822488|uniprotkb:Q6I233|uniprotkb:Q6KVW9	psi-mi:gde1_human(display_long)|uniprotkb:GDE1(gene name)|psi-mi:GDE1(display_short)|uniprotkb:MIR16(gene name synonym)|uniprotkb:Membrane-interacting protein of RGS16(gene name synonym)|uniprotkb:RGS16-interacting membrane protein(gene name synonym)|uniprotkb:Glycerophosphoinositol glycerophosphodiesterase GDE1(gene name synonym)|uniprotkb:Lysophospholipase D GDE1(gene name synonym)	psi-mi:cpfc2_bacan(display_long)|uniprotkb:cpfC2(gene name)|psi-mi:cpfC2(display_short)|uniprotkb:hemH-2(gene name synonym)|uniprotkb:hemH2(gene name synonym)|uniprotkb:BAS1075(locus name)|uniprotkb:BA_1158(locus name)|uniprotkb:GBAA_1158(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833337|imex:IM-13779-3749	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000006007.12(gene)|ensembl:ENST00000353258.8(transcript)|go:""GO:0004622""(lysophospholipase activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006580""(ethanolamine metabolic process)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0006644""(phospholipid metabolic process)|go:""GO:0008889""(glycerophosphodiester phosphodiesterase activity)|go:""GO:0016020""(membrane)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0046475""(glycerophospholipid catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0047395""(glycerophosphoinositol glycerophosphodiesterase activity)|go:""GO:0070291""(N-acylethanolamine metabolic process)|interpro:IPR017946|interpro:IPR030395|mint:Q9NZC3|reactome:R-HSA-6814848|refseq:NP_057725.1|panther:PTHR46320(orthology-group)"	"interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|interpro:IPR033644|interpro:IPR033659|go:""GO:0004325""(ferrochelatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:NP_843640.1|refseq:YP_027347.1|refseq:WP_000727371.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IqbBCJ0zS+ZXYiL5Fm8ha7QrxCs9606	rogid:obnRdfnUE+dKI0qsKs06usLG16E1392	intact-crc:081BF21CD342BA6D|rigid:blVRMh8XihQ1hiV6mZw6W37kIK0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H3P7	uniprotkb:A0A6L8P457	intact:EBI-1791792|ensembl:ENSP00000355777.5|uniprotkb:Q5VTJ0|uniprotkb:Q6P9F1|uniprotkb:Q8IZC5|uniprotkb:Q8N4D6|uniprotkb:Q9H6U3|uniprotkb:B2RB29	intact:EBI-2813172|uniprotkb:Q6HS51|uniprotkb:Q6KLF1|uniprotkb:E9R1V4|uniprotkb:E9R1V5|uniprotkb:A0A2P0HJY3|uniprotkb:Q81KP6	psi-mi:gcp60_human(display_long)|uniprotkb:GOCAP1(gene name synonym)|uniprotkb:GOLPH1(gene name synonym)|uniprotkb:ACBD3(gene name)|psi-mi:ACBD3(display_short)|uniprotkb:GCP60(gene name synonym)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym)	psi-mi:a0a6l8p457_bacan(display_long)|uniprotkb:GBAA_4947(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833351|imex:IM-13779-3748	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000182827.9(gene)|ensembl:ENST00000366812.6(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005739""(mitochondrion)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006694""(steroid biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0034237""(protein kinase A regulatory subunit binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR009038(GOLD)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|interpro:IPR036598|interpro:IPR052269|mint:Q9H3P7|rcsb pdb:2N72|rcsb pdb:2N73|rcsb pdb:5LZ1|rcsb pdb:5LZ3|rcsb pdb:5LZ6|rcsb pdb:5TDQ|rcsb pdb:6HLN|rcsb pdb:6HLT|rcsb pdb:6HLV|rcsb pdb:6HLW|rcsb pdb:6HM8|rcsb pdb:6HMV|reactome:R-HSA-432722|refseq:NP_073572.2|dip:DIP-40673N|panther:PTHR22973(orthology-group)"	"refseq:WP_001031503.1|interpro:IPR008007(Peptidase M42)|interpro:IPR023367|interpro:IPR051464|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:jAaMXnoXG6RGj+lAgIYk1inXA6o9606	rogid:gc3DYbVKwIN0x2KHiydixpUDIW41392	intact-crc:71AB0A060942267C|rigid:f1oZvAn2fQ3k1jeSC7401FJFqwM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PD01	uniprotkb:P23378	intact:EBI-2810689|uniprotkb:Q6KR00|uniprotkb:Q6HWW8|uniprotkb:E9QQS7|uniprotkb:E9QQS8|uniprotkb:Q81NP8	intact:EBI-2509907|uniprotkb:Q2M2F8|ensembl:ENSP00000370737.4	psi-mi:a0a6l8pd01_bacan(display_long)|uniprotkb:GBAA_3131(locus name)	"psi-mi:gcsp_human(display_long)|uniprotkb:GLDC(gene name)|psi-mi:GLDC(display_short)|uniprotkb:GCSP(gene name synonym)|uniprotkb:Glycine decarboxylase(gene name synonym)|uniprotkb:Glycine cleavage system P protein(gene name synonym)|uniprotkb:""Glycine dehydrogenase (aminomethyl-transferring)""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833344|imex:IM-13779-3745	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016491""(oxidoreductase activity)|interpro:IPR036291|refseq:WP_000649082.1"	"efo:""Orphanet:289857""|efo:""Orphanet:289860""|efo:""Orphanet:289863""|ensembl:ENSG00000178445.10(gene)|ensembl:ENST00000321612.8(transcript)|go:""GO:0004375""(""glycine dehydrogenase (decarboxylating) activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005886""(plasma membrane)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0006546""(glycine catabolic process)|go:""GO:0009055""(electron transfer activity)|go:""GO:0016594""(glycine binding)|go:""GO:0016829""(lyase activity)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0036255""(response to methylamine)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0070280""(pyridoxal binding)|go:""GO:1903442""(response to lipoic acid)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR001597(Aromatic amino acid beta-eliminating lyase/threonine aldolase)|interpro:IPR003437(Glycine cleavage system P-protein)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020581|interpro:IPR049315|interpro:IPR049316|mint:P23378|rcsb pdb:6I33|rcsb pdb:6I34|rcsb pdb:6I35|reactome:R-HSA-6783984|refseq:NP_000161.2|panther:PTHR11773(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zX4+aIdzhDeWoVC9l0OlbVnHVow1392	rogid:zNBF42twnLftxt9dEQsTcGD5dts9606	intact-crc:35517D83ED4F8BA9|rigid:r5LkLCA17Eu8IziR92JFn/J1hTw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3A9S2	uniprotkb:P23378	intact:EBI-2814999|uniprotkb:Q6KKF8|uniprotkb:Q6HR42|uniprotkb:E9RAH1|uniprotkb:E9RAH2|uniprotkb:Q81XA6|uniprotkb:A0A0F7R9X6	intact:EBI-2509907|uniprotkb:Q2M2F8|ensembl:ENSP00000370737.4	psi-mi:a0a6h3a9s2_bacan(display_long)|uniprotkb:GBAA_5334(locus name)|uniprotkb:vacB(gene name)|psi-mi:vacB(display_short)|uniprotkb:rnr(gene name synonym)	"psi-mi:gcsp_human(display_long)|uniprotkb:GLDC(gene name)|psi-mi:GLDC(display_short)|uniprotkb:GCSP(gene name synonym)|uniprotkb:Glycine decarboxylase(gene name synonym)|uniprotkb:Glycine cleavage system P protein(gene name synonym)|uniprotkb:""Glycine dehydrogenase (aminomethyl-transferring)""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833365|imex:IM-13779-3747	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR022966|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011805(Ribonuclease R, bacterial)|interpro:IPR050180|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008859""(exoribonuclease II activity)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR040476|refseq:WP_000391091.1"	"efo:""Orphanet:289857""|efo:""Orphanet:289860""|efo:""Orphanet:289863""|ensembl:ENSG00000178445.10(gene)|ensembl:ENST00000321612.8(transcript)|go:""GO:0004375""(""glycine dehydrogenase (decarboxylating) activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005886""(plasma membrane)|go:""GO:0005960""(glycine cleavage complex)|go:""GO:0006546""(glycine catabolic process)|go:""GO:0009055""(electron transfer activity)|go:""GO:0016594""(glycine binding)|go:""GO:0016829""(lyase activity)|go:""GO:0019464""(glycine decarboxylation via glycine cleavage system)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0036255""(response to methylamine)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0070280""(pyridoxal binding)|go:""GO:1903442""(response to lipoic acid)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR001597(Aromatic amino acid beta-eliminating lyase/threonine aldolase)|interpro:IPR003437(Glycine cleavage system P-protein)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020581|interpro:IPR049315|interpro:IPR049316|mint:P23378|rcsb pdb:6I33|rcsb pdb:6I34|rcsb pdb:6I35|reactome:R-HSA-6783984|refseq:NP_000161.2|panther:PTHR11773(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xfZ8oFOsdvZkWwfs05cFLCd+3ag1392	rogid:zNBF42twnLftxt9dEQsTcGD5dts9606	intact-crc:3D3CF576AB66B90D|rigid:Mt3JCnMlof4QaORW8FyWGUAoR1o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BSJ2	uniprotkb:Q81P27	intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936.3|ensembl:ENSP00000506731.1|ensembl:ENSP00000507482.1|ensembl:ENSP00000507610.1|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0	intact:EBI-2814639|uniprotkb:Q6KRC1|uniprotkb:Q6HX99	psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym)	psi-mi:proa_bacan(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:BA_2992(locus name)|uniprotkb:GBAA_2992(locus name)|uniprotkb:BAS2781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833358|imex:IM-13779-3746	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000130640.15(gene)|ensembl:ENST00000252936.8(transcript)|ensembl:ENST00000682123.1(transcript)|ensembl:ENST00000682515.1(transcript)|ensembl:ENST00000683612.1(transcript)|go:""GO:0000278""(mitotic cell cycle)|go:""GO:0000922""(spindle pole)|go:""GO:0000930""(gamma-tubulin complex)|go:""GO:0001764""(neuron migration)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005881""(cytoplasmic microtubule)|go:""GO:0007020""(microtubule nucleation)|go:""GO:0007420""(brain development)|go:""GO:0016020""(membrane)|go:""GO:0031122""(cytoplasmic microtubule organization)|go:""GO:0043015""(gamma-tubulin binding)|go:""GO:0051225""(spindle assembly)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|rcsb pdb:7QJ0|rcsb pdb:7QJ1|rcsb pdb:7QJ2|rcsb pdb:7QJ3|rcsb pdb:7QJ4|rcsb pdb:7QJ5|rcsb pdb:7QJ6|rcsb pdb:7QJ7|rcsb pdb:7QJ8|rcsb pdb:7QJ9|rcsb pdb:7QJA|rcsb pdb:7QJB|rcsb pdb:7QJC|rcsb pdb:7QJD|rcsb pdb:8Q62|rcsb pdb:8RX1|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|reactome:R-HSA-380270|reactome:R-HSA-380320|refseq:NP_006650.1|refseq:NP_001243547.1|refseq:NP_001243546.1|panther:PTHR19302(orthology-group)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|go:""GO:0004350""(glutamate-5-semialdehyde dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0050661""(NADP binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:NP_845325.1|refseq:YP_029039.1|refseq:WP_001006638.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606	rogid:2iR76/3cLX7gyVDMLNG2KEyBoMY1392	intact-crc:487986DE257036DA|rigid:KcfwC4jDYk/MyJ79avBteFRbcPE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3A8V4	uniprotkb:Q96CN9	intact:EBI-2810133|uniprotkb:A0A1J9WG58|uniprotkb:Q6KWL8|uniprotkb:Q6I2T9|uniprotkb:E9RC14|uniprotkb:E9RC15|uniprotkb:Q81UL0|uniprotkb:A0A2B8HWP9	intact:EBI-746252|ensembl:ENSP00000318821.2|uniprotkb:Q9H6N7	psi-mi:a0a6h3a8v4_bacan(display_long)|uniprotkb:sasP1(gene name)|psi-mi:sasP1(display_short)|uniprotkb:GBAA_0858(locus name)	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833405|imex:IM-13779-3754	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001448(Small acid-soluble spore protein, alpha/beta type)|interpro:IPR018126|refseq:WP_000013338.1|interpro:IPR050847|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0006265""(DNA topological change)|interpro:IPR038300"	"ensembl:ENSG00000179562.3(gene)|ensembl:ENST00000321407.3(transcript)|go:""GO:0000138""(Golgi trans cisterna)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0031267""(small GTPase binding)|interpro:IPR000237(GRIP)|interpro:IPR051952|mint:Q96CN9|reactome:R-HSA-6811440|refseq:NP_078799.2|panther:PTHR23157(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:L0kfSsXpT8asMqUkNwqi8XwOx8s1392	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	intact-crc:5E4CEA71BBBA4EA2|rigid:NlJon9j+UH4qUitBRAiYRs42CZI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P77819	uniprotkb:Q96CN9	intact:EBI-2822888|uniprotkb:Q6I4U1|uniprotkb:Q6KYI7|uniprotkb:Q81VT7	intact:EBI-746252|ensembl:ENSP00000318821.2|uniprotkb:Q9H6N7	psi-mi:rpoc_bacan(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:RNA polymerase subunit beta'(gene name synonym)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:BA_0103(locus name)|uniprotkb:GBAA_0103(locus name)|uniprotkb:BAS0103(locus name)	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833398|imex:IM-13779-3752	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0008270""(zinc ion binding)|refseq:WP_000567940.1|interpro:IPR038120|interpro:IPR042102|refseq:NP_842671.2|refseq:YP_026389.1|interpro:IPR044893|interpro:IPR045867"	"ensembl:ENSG00000179562.3(gene)|ensembl:ENST00000321407.3(transcript)|go:""GO:0000138""(Golgi trans cisterna)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0031267""(small GTPase binding)|interpro:IPR000237(GRIP)|interpro:IPR051952|mint:Q96CN9|reactome:R-HSA-6811440|refseq:NP_078799.2|panther:PTHR23157(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fj+tcN8jEU71jFxqbSrMsyCyJf01392	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	intact-crc:19E62127D8D6E8E7|rigid:J5Hf7DjNRZRFr6nU1bOeZkoqgFQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IWJ2	uniprotkb:A0A6L7HSZ9	intact:EBI-1645320|uniprotkb:O15045|uniprotkb:Q4ZG46|uniprotkb:Q8TDH3|uniprotkb:Q9H2G8|uniprotkb:A6H8X8|intact:EBI-1645335|ensembl:ENSP00000307939.5|intact:EBI-28984280	intact:EBI-2811304|uniprotkb:Q6KXZ4|uniprotkb:Q6I488|uniprotkb:E9R4T3|uniprotkb:E9R4T4|uniprotkb:Q81ZE2|uniprotkb:A0A1V4B8A9	psi-mi:gcc2_human(display_long)|uniprotkb:GCC2(gene name)|psi-mi:GCC2(display_short)|uniprotkb:KIAA0336(gene name synonym)|uniprotkb:RANBP2L4(gene name synonym)|uniprotkb:185 kDa Golgi coiled-coil protein(gene name synonym)|uniprotkb:Ran-binding protein 2-like 4(gene name synonym)|uniprotkb:CTCL tumor antigen se1-1(gene name synonym)|uniprotkb:CLL-associated antigen KW-11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-53(gene name synonym)	psi-mi:a0a6l7hsz9_bacan(display_long)|uniprotkb:gabD(gene name)|psi-mi:gabD(display_short)|uniprotkb:GBAA_0327(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833391|imex:IM-13779-3751	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_852118.1|refseq:XP_006712934.1|ensembl:ENSG00000135968.22(gene)|ensembl:ENST00000309863.11(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0016020""(membrane)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0034499""(late endosome to Golgi transport)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0070861""(regulation of protein exit from endoplasmic reticulum)|go:""GO:0071955""(recycling endosome to Golgi transport)|go:""GO:0090161""(Golgi ribbon formation)|interpro:IPR000237(GRIP)|interpro:IPR032023|interpro:IPR051841|rcsb pdb:3BBP|reactome:R-HSA-6811440|reactome:R-HSA-9725370|panther:PTHR18902(orthology-group)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR010102(Succinic semialdehyde dehydrogenase)|interpro:IPR050740|go:""GO:0004777""(""succinate-semialdehyde dehydrogenase (NAD+) activity"")|go:""GO:0009450""(gamma-aminobutyric acid catabolic process)|refseq:WP_000358103.1|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YeL/V7QABi3DbamH+qE6WfFLAco9606	rogid:IKDmk6KMXo8kwWQowTVtLRljgHY1392	intact-crc:C9C11DA5DC611EA4|rigid:14B1+hyD5aDtvoMtZNSUR991MWc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81LY8	uniprotkb:Q8IWJ2	intact:EBI-2833372|uniprotkb:Q6HTE1|uniprotkb:Q6KMN3	intact:EBI-1645320|uniprotkb:O15045|uniprotkb:Q4ZG46|uniprotkb:Q8TDH3|uniprotkb:Q9H2G8|uniprotkb:A6H8X8|intact:EBI-1645335|ensembl:ENSP00000307939.5|intact:EBI-28984280	psi-mi:tcyp_bacan(display_long)|uniprotkb:Transporter of cystine TcyP(gene name synonym)|uniprotkb:BAS4148(locus name)|uniprotkb:BA_4469(locus name)|uniprotkb:GBAA_4469(locus name)	psi-mi:gcc2_human(display_long)|uniprotkb:GCC2(gene name)|psi-mi:GCC2(display_short)|uniprotkb:KIAA0336(gene name synonym)|uniprotkb:RANBP2L4(gene name synonym)|uniprotkb:185 kDa Golgi coiled-coil protein(gene name synonym)|uniprotkb:Ran-binding protein 2-like 4(gene name synonym)|uniprotkb:CTCL tumor antigen se1-1(gene name synonym)|uniprotkb:CLL-associated antigen KW-11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-53(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833377|imex:IM-13779-3750	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0015184""(L-cystine transmembrane transporter activity)|go:""GO:0015293""(symporter activity)|interpro:IPR001991(""Sodium:dicarboxylate symporter"")|refseq:WP_001094329.1|interpro:IPR036458|refseq:NP_846695.1|refseq:YP_030397.1"	"refseq:NP_852118.1|refseq:XP_006712934.1|ensembl:ENSG00000135968.22(gene)|ensembl:ENST00000309863.11(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0016020""(membrane)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0034499""(late endosome to Golgi transport)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0070861""(regulation of protein exit from endoplasmic reticulum)|go:""GO:0071955""(recycling endosome to Golgi transport)|go:""GO:0090161""(Golgi ribbon formation)|interpro:IPR000237(GRIP)|interpro:IPR032023|interpro:IPR051841|rcsb pdb:3BBP|reactome:R-HSA-6811440|reactome:R-HSA-9725370|panther:PTHR18902(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Mf70qNgozkOraafDxeyvAbbiIzQ1392	rogid:YeL/V7QABi3DbamH+qE6WfFLAco9606	intact-crc:7CBA082E3AC75FB4|rigid:ye4AMRh72zcBZm8Tr/0IdlgegxY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81Y46	uniprotkb:Q8IWJ2	intact:EBI-2812495|uniprotkb:Q6KPL0|uniprotkb:Q6HVE1	intact:EBI-1645320|uniprotkb:O15045|uniprotkb:Q4ZG46|uniprotkb:Q8TDH3|uniprotkb:Q9H2G8|uniprotkb:A6H8X8|intact:EBI-1645335|ensembl:ENSP00000307939.5|intact:EBI-28984280	psi-mi:hutu_bacan(display_long)|uniprotkb:hutU(gene name)|psi-mi:hutU(display_short)|uniprotkb:Imidazolonepropionate hydrolase(gene name synonym)|uniprotkb:BA_3711(locus name)|uniprotkb:GBAA_3711(locus name)|uniprotkb:BAS3441(locus name)	psi-mi:gcc2_human(display_long)|uniprotkb:GCC2(gene name)|psi-mi:GCC2(display_short)|uniprotkb:KIAA0336(gene name synonym)|uniprotkb:RANBP2L4(gene name synonym)|uniprotkb:185 kDa Golgi coiled-coil protein(gene name synonym)|uniprotkb:Ran-binding protein 2-like 4(gene name synonym)|uniprotkb:CTCL tumor antigen se1-1(gene name synonym)|uniprotkb:CLL-associated antigen KW-11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-53(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833384|imex:IM-13779-3753	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR035085|interpro:IPR023636|interpro:IPR023637|go:""GO:0005737""(cytoplasm)|go:""GO:0016153""(urocanate hydratase activity)|go:""GO:0019556""(L-histidine catabolic process to glutamate and formamide)|go:""GO:0019557""(L-histidine catabolic process to glutamate and formate)|refseq:WP_000416715.1|interpro:IPR038364|interpro:IPR035401|interpro:IPR035400|interpro:IPR036190|refseq:NP_845974.1|refseq:YP_029697.1"	"refseq:NP_852118.1|refseq:XP_006712934.1|ensembl:ENSG00000135968.22(gene)|ensembl:ENST00000309863.11(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0016020""(membrane)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0034499""(late endosome to Golgi transport)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0070861""(regulation of protein exit from endoplasmic reticulum)|go:""GO:0071955""(recycling endosome to Golgi transport)|go:""GO:0090161""(Golgi ribbon formation)|interpro:IPR000237(GRIP)|interpro:IPR032023|interpro:IPR051841|rcsb pdb:3BBP|reactome:R-HSA-6811440|reactome:R-HSA-9725370|panther:PTHR18902(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bokqO9GavtjceeT8eQKHFW32guU1392	rogid:YeL/V7QABi3DbamH+qE6WfFLAco9606	intact-crc:03B8AD2E39FE54AF|rigid:LCTtTHYtcji2HITq077TuXG4Uug	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PL93	uniprotkb:O95166	intact:EBI-2812142|uniprotkb:Q6HXW8|uniprotkb:Q6KRZ0|uniprotkb:E9R374|uniprotkb:E9R375|uniprotkb:Q81PQ4|uniprotkb:A0A0F7RGT7	intact:EBI-712001|ensembl:ENSP00000306866.5	psi-mi:a0a6l8pl93_bacan(display_long)|uniprotkb:ypeB(gene name)|psi-mi:ypeB(display_short)|uniprotkb:GBAA_2747(locus name)	"psi-mi:gbrap_human(display_long)|uniprotkb:""GABA(A) receptor-associated protein""(gene name synonym)|uniprotkb:MM46(gene name synonym)|uniprotkb:GABARAP(gene name)|psi-mi:GABARAP(display_short)|uniprotkb:FLC3B(gene name synonym)|uniprotkb:HT004(orf name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833424|imex:IM-13779-3755	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014239(Spore germination YpeB)|go:""GO:0009847""(spore germination)|refseq:WP_000943708.1|interpro:IPR025711|interpro:IPR048402"	"ensembl:ENSG00000170296.10(gene)|ensembl:ENST00000302386.10(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0000423""(mitophagy)|go:""GO:0005764""(lysosome)|go:""GO:0005776""(autophagosome)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0005875""(microtubule associated complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0005930""(axoneme)|go:""GO:0006605""(protein targeting)|go:""GO:0006995""(cellular response to nitrogen starvation)|go:""GO:0007268""(chemical synaptic transmission)|go:""GO:0008017""(microtubule binding)|go:""GO:0008429""(phosphatidylethanolamine binding)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0015031""(protein transport)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0035020""(regulation of Rac protein signal transduction)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0050811""(GABA receptor binding)|go:""GO:0097225""(sperm midpiece)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098696""(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:1902524""(positive regulation of protein K48-linked ubiquitination)|interpro:IPR004241(""Light chain 3 (LC3)"")|interpro:IPR029071|mint:O95166|rcsb pdb:1GNU|rcsb pdb:1KLV|rcsb pdb:1KM7|rcsb pdb:1KOT|rcsb pdb:3D32|rcsb pdb:3DOW|rcsb pdb:3WIM|rcsb pdb:4XC2|rcsb pdb:5DPS|rcsb pdb:6HB9|rcsb pdb:6HOG|rcsb pdb:6HOH|rcsb pdb:6HOJ|rcsb pdb:6HOK|rcsb pdb:6HYL|rcsb pdb:6HYM|rcsb pdb:6HYN|rcsb pdb:6HYO|rcsb pdb:6YOP|rcsb pdb:7AA8|rcsb pdb:7BRQ|rcsb pdb:7BRT|rcsb pdb:7BRU|rcsb pdb:7BV4|rcsb pdb:7EA7|rcsb pdb:7LSW|rcsb pdb:7LT6|rcsb pdb:7VEC|rcsb pdb:7VED|rcsb pdb:7YO9|rcsb pdb:7ZKR|rcsb pdb:7ZL7|rcsb pdb:8AFI|rcsb pdb:8S1M|rcsb pdb:8T2M|rcsb pdb:8T2N|rcsb pdb:8T31|rcsb pdb:8T32|rcsb pdb:8T33|rcsb pdb:8W6A|reactome:R-HSA-1632852|reactome:R-HSA-8854214|refseq:NP_009209.1|dip:DIP-35050N|panther:PTHR10969(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:ArcU2AZZMp9ttGHYayHY+K9lpzU1392	rogid:PRC57VUrKgXozj1jnvgz7MQERK09606	intact-crc:90674D4859967235|rigid:gMhEIlU3cV1gYtGaEz8urCkktxE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IWJ2	uniprotkb:A0A0F7RJC6	intact:EBI-1645320|uniprotkb:O15045|uniprotkb:Q4ZG46|uniprotkb:Q8TDH3|uniprotkb:Q9H2G8|uniprotkb:A6H8X8|intact:EBI-1645335|ensembl:ENSP00000307939.5|intact:EBI-28984280	intact:EBI-2833415|uniprotkb:Q6KU60|uniprotkb:Q6I088|uniprotkb:E9QY55|uniprotkb:E9QY56|uniprotkb:Q81S06	psi-mi:gcc2_human(display_long)|uniprotkb:GCC2(gene name)|psi-mi:GCC2(display_short)|uniprotkb:KIAA0336(gene name synonym)|uniprotkb:RANBP2L4(gene name synonym)|uniprotkb:185 kDa Golgi coiled-coil protein(gene name synonym)|uniprotkb:Ran-binding protein 2-like 4(gene name synonym)|uniprotkb:CTCL tumor antigen se1-1(gene name synonym)|uniprotkb:CLL-associated antigen KW-11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-53(gene name synonym)	psi-mi:a0a0f7rjc6_bacan(display_long)|uniprotkb:GBAA_1874(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833412|imex:IM-13779-3759	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_852118.1|refseq:XP_006712934.1|ensembl:ENSG00000135968.22(gene)|ensembl:ENST00000309863.11(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0016020""(membrane)|go:""GO:0031023""(microtubule organizing center organization)|go:""GO:0031267""(small GTPase binding)|go:""GO:0034067""(protein localization to Golgi apparatus)|go:""GO:0034453""(microtubule anchoring)|go:""GO:0034499""(late endosome to Golgi transport)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0042802""(identical protein binding)|go:""GO:0070861""(regulation of protein exit from endoplasmic reticulum)|go:""GO:0071955""(recycling endosome to Golgi transport)|go:""GO:0090161""(Golgi ribbon formation)|interpro:IPR000237(GRIP)|interpro:IPR032023|interpro:IPR051841|rcsb pdb:3BBP|reactome:R-HSA-6811440|reactome:R-HSA-9725370|panther:PTHR18902(orthology-group)"	"go:""GO:0008168""(methyltransferase activity)|interpro:IPR029063|interpro:IPR013217(Methyltransferase type 12)|refseq:WP_011053137.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YeL/V7QABi3DbamH+qE6WfFLAco9606	rogid:CwVPbfsD5kop2G+x7zdk71nU+HA1392	intact-crc:FBDF484D6A86C233|rigid:HiTq77bVzZ/9VTe8sBSxje2Z3Ug	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63244	uniprotkb:A0A6L8PL93	intact:EBI-296739|uniprotkb:P25388|ensembl:ENSP00000426909.1|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	intact:EBI-2812142|uniprotkb:Q6HXW8|uniprotkb:Q6KRZ0|uniprotkb:E9R374|uniprotkb:E9R375|uniprotkb:Q81PQ4|uniprotkb:A0A0F7RGT7	psi-mi:rack1_human(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Receptor of activated protein C kinase 1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)	psi-mi:a0a6l8pl93_bacan(display_long)|uniprotkb:ypeB(gene name)|psi-mi:ypeB(display_short)|uniprotkb:GBAA_2747(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833438|imex:IM-13779-3756	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204628.12(gene)|ensembl:ENST00000512805.6(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007369""(gastrulation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015935""(small ribosomal subunit)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030332""(cyclin binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042998""(positive regulation of Golgi to plasma membrane protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043204""(perikaryon)|go:""GO:0043473""(pigmentation)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045296""(cadherin binding)|refseq:NP_006089.1|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048511""(rhythmic process)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051901""(positive regulation of mitochondrial depolarization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0106070""(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:1900102""(negative regulation of endoplasmic reticulum unfolded protein response)|go:""GO:1903751""(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:1990630""(IRE1-RACK1-PP2A complex)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000543""(positive regulation of gastrulation)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001125""(negative regulation of translational frameshifting)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR045223|mint:P63244|rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|dip:DIP-46736N|panther:PTHR19868(orthology-group)"	"interpro:IPR014239(Spore germination YpeB)|go:""GO:0009847""(spore germination)|refseq:WP_000943708.1|interpro:IPR025711|interpro:IPR048402"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	rogid:ArcU2AZZMp9ttGHYayHY+K9lpzU1392	intact-crc:6F31FA142EB8A2B7|rigid:QWpFr1Pj0/nX2ofWaR9CKzjrAkQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P32456	uniprotkb:A0A348ACF3	intact:EBI-714388|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2|ensembl:ENSP00000359497.3|ensembl:ENSP00000434282.1	intact:EBI-2825270|uniprotkb:Q6KK05|uniprotkb:Q6HQN2|uniprotkb:E9QXX7|uniprotkb:E9QXX8|uniprotkb:A0A2P0HL50|uniprotkb:Q81K32	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:a0a348acf3_bacan(display_long)|uniprotkb:GBAA_5509(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833431|imex:IM-13779-3758	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004111.2|ensembl:ENSG00000162645.13(gene)|ensembl:ENST00000370466.4(transcript)|ensembl:ENST00000464839.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003924""(GTPase activity)|go:""GO:0004866""(endopeptidase inhibitor activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006955""(immune response)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042832""(defense response to protozoan)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:0051607""(defense response to virus)|go:""GO:0051715""(cytolysis in another organism)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0071347""(cellular response to interleukin-1)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0140639""(positive regulation of pyroptotic inflammatory response)|go:""GO:0140678""(molecular function inhibitor activity)|go:""GO:0140973""(positive regulation of AIM2 inflammasome complex assembly)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:P32456|rcsb pdb:6VKJ|rcsb pdb:7E58|rcsb pdb:7M1S|reactome:R-HSA-877300|reactome:R-HSA-909733|panther:PTHR10751(orthology-group)"	"interpro:IPR003331(UDP-N-acetylglucosamine 2-epimerase)|rcsb pdb:3BEO|interpro:IPR029767|go:""GO:0000166""(nucleotide binding)|go:""GO:0008761""(UDP-N-acetylglucosamine 2-epimerase activity)|refseq:WP_000140133.1|rcsb pdb:8AHE|rcsb pdb:8AHF"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:bTKZlRi7ghV2MC5/l4YjrS3ESV81392	intact-crc:BA14C06FC938C0E6|rigid:P2gcE4mQ9oHDe6j9UTj6pfx7kgs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63244	uniprotkb:Q6KMS8	intact:EBI-296739|uniprotkb:P25388|ensembl:ENSP00000426909.1|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	intact:EBI-2812678|uniprotkb:Q81M34|uniprotkb:Q6HTI7	psi-mi:rack1_human(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Receptor of activated protein C kinase 1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)	psi-mi:efp_bacan(display_long)|uniprotkb:efp(gene name)|psi-mi:efp(display_short)|uniprotkb:BA_4421(locus name)|uniprotkb:GBAA_4421(locus name)|uniprotkb:BAS4101(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833445|imex:IM-13779-3757	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204628.12(gene)|ensembl:ENST00000512805.6(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007369""(gastrulation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015935""(small ribosomal subunit)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030332""(cyclin binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042998""(positive regulation of Golgi to plasma membrane protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043204""(perikaryon)|go:""GO:0043473""(pigmentation)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045296""(cadherin binding)|refseq:NP_006089.1|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048511""(rhythmic process)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051901""(positive regulation of mitochondrial depolarization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0106070""(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:1900102""(negative regulation of endoplasmic reticulum unfolded protein response)|go:""GO:1903751""(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:1990630""(IRE1-RACK1-PP2A complex)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000543""(positive regulation of gastrulation)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001125""(negative regulation of translational frameshifting)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR045223|mint:P63244|rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|dip:DIP-46736N|panther:PTHR19868(orthology-group)"	"interpro:IPR015365(Elongation factor P, C-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR020599|interpro:IPR013185(Translation elongation factor, KOW-like)|interpro:IPR001059(Translation elongation factor P/YeiP, central)|interpro:IPR013852(Translation elongation factor P/YeiP, conserved site)|interpro:IPR011768(Translation elongation factor P)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0043043""(peptide biosynthetic process)|refseq:WP_000626507.1|refseq:YP_030351.1|refseq:NP_846649.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	rogid:IbRpaP4LNDHuGJwbXfefgJ5Xgc81392	intact-crc:FBCEA4D92C865F2B|rigid:BxMzBjVMNtNOjh78bCxG2s4qzEg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63244	uniprotkb:Q81U22	intact:EBI-296739|uniprotkb:P25388|ensembl:ENSP00000426909.1|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	intact:EBI-2814904|uniprotkb:Q6KW38|uniprotkb:Q6I2A7	psi-mi:rack1_human(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Receptor of activated protein C kinase 1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)	psi-mi:cpfc1_bacan(display_long)|uniprotkb:cpfC1(gene name)|psi-mi:cpfC1(display_short)|uniprotkb:hemH-1(gene name synonym)|uniprotkb:hemH1(gene name synonym)|uniprotkb:BAS1000(locus name)|uniprotkb:BA_1071(locus name)|uniprotkb:GBAA_1071(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833452|imex:IM-13779-3760	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204628.12(gene)|ensembl:ENST00000512805.6(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007369""(gastrulation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015935""(small ribosomal subunit)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030332""(cyclin binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042998""(positive regulation of Golgi to plasma membrane protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043204""(perikaryon)|go:""GO:0043473""(pigmentation)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045296""(cadherin binding)|refseq:NP_006089.1|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048511""(rhythmic process)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051901""(positive regulation of mitochondrial depolarization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0106070""(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:1900102""(negative regulation of endoplasmic reticulum unfolded protein response)|go:""GO:1903751""(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:1990630""(IRE1-RACK1-PP2A complex)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000543""(positive regulation of gastrulation)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001125""(negative regulation of translational frameshifting)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR045223|mint:P63244|rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|dip:DIP-46736N|panther:PTHR19868(orthology-group)"	"interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|rcsb pdb:2C8J|interpro:IPR033644|interpro:IPR033659|go:""GO:0004325""(ferrochelatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:NP_843565.1|refseq:YP_027273.1|refseq:WP_000726793.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	rogid:VgwkMIvazgaeCD8Rq+iY6Sn7gk01392	intact-crc:7F3282C780CF3E0B|rigid:4jkOh144Pee5hlfvgTkkptDQHLg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H0W6	uniprotkb:P63244	intact:EBI-2833469|uniprotkb:Q6KP27|uniprotkb:Q6HUV0|uniprotkb:E9QRI3|uniprotkb:E9QRI4|uniprotkb:Q81WP7|uniprotkb:A0A0F7RDB0	intact:EBI-296739|uniprotkb:P25388|ensembl:ENSP00000426909.1|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	psi-mi:a0a6l7h0w6_bacan(display_long)|uniprotkb:GBAA_3922(locus name)	psi-mi:rack1_human(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Receptor of activated protein C kinase 1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833466|imex:IM-13779-3761	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR007863(Peptidase M16, C-terminal)|refseq:WP_000411960.1|interpro:IPR050361"	"ensembl:ENSG00000204628.12(gene)|ensembl:ENST00000512805.6(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007369""(gastrulation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015935""(small ribosomal subunit)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030332""(cyclin binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042998""(positive regulation of Golgi to plasma membrane protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043204""(perikaryon)|go:""GO:0043473""(pigmentation)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045296""(cadherin binding)|refseq:NP_006089.1|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048511""(rhythmic process)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051901""(positive regulation of mitochondrial depolarization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0106070""(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:1900102""(negative regulation of endoplasmic reticulum unfolded protein response)|go:""GO:1903751""(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:1990630""(IRE1-RACK1-PP2A complex)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000543""(positive regulation of gastrulation)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001125""(negative regulation of translational frameshifting)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR045223|mint:P63244|rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|dip:DIP-46736N|panther:PTHR19868(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:VWQFfDE7OruJKM/7PzoYMlOec001392	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	intact-crc:4CAB63F50A12C28B|rigid:5e6uBt9nWZgRX6LqukhXTFUI97I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81UI7	uniprotkb:P63244	intact:EBI-2815395|uniprotkb:Q6KWJ7|uniprotkb:Q6I2R6	intact:EBI-296739|uniprotkb:P25388|ensembl:ENSP00000426909.1|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	psi-mi:seca2_bacan(display_long)|uniprotkb:secA2(gene name)|psi-mi:secA2(display_short)|uniprotkb:BA_0882(locus name)|uniprotkb:GBAA_0882(locus name)|uniprotkb:BAS0838(locus name)	psi-mi:rack1_human(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Receptor of activated protein C kinase 1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833459|imex:IM-13779-3763	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR044722|interpro:IPR030908|interpro:IPR000185(SecA protein)|interpro:IPR020937|interpro:IPR011115(SecA DEAD-like)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0008564""(protein-exporting ATPase activity)|go:""GO:0017038""(protein import)|go:""GO:0031522""(cell envelope Sec protein transport complex)|go:""GO:0043952""(protein transport by the Sec complex)|go:""GO:0065002""(intracellular protein transmembrane transport)|refseq:WP_000935179.1|interpro:IPR036266|interpro:IPR036670|refseq:NP_843394.1|refseq:YP_027114.1"	"ensembl:ENSG00000204628.12(gene)|ensembl:ENST00000512805.6(transcript)|go:""GO:0001891""(phagocytic cup)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0002181""(cytoplasmic translation)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007369""(gastrulation)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008200""(ion channel inhibitor activity)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015935""(small ribosomal subunit)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0030292""(protein tyrosine kinase inhibitor activity)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030332""(cyclin binding)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030425""(dendrite)|go:""GO:0030496""(midbody)|go:""GO:0030971""(receptor tyrosine kinase binding)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0032436""(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033137""(negative regulation of peptidyl-serine phosphorylation)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0042169""(SH2 domain binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0042998""(positive regulation of Golgi to plasma membrane protein transport)|go:""GO:0043022""(ribosome binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043204""(perikaryon)|go:""GO:0043473""(pigmentation)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0045182""(translation regulator activity)|go:""GO:0045296""(cadherin binding)|refseq:NP_006089.1|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048511""(rhythmic process)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051434""(BH3 domain binding)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051901""(positive regulation of mitochondrial depolarization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0072344""(rescue of stalled ribosome)|go:""GO:0106070""(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:1900102""(negative regulation of endoplasmic reticulum unfolded protein response)|go:""GO:1903751""(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:""GO:1990630""(IRE1-RACK1-PP2A complex)|go:""GO:2000114""(regulation of establishment of cell polarity)|go:""GO:2000543""(positive regulation of gastrulation)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001125""(negative regulation of translational frameshifting)|go:""GO:2001244""(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR045223|mint:P63244|rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:7R4X|rcsb pdb:7TQL|rcsb pdb:7XNX|rcsb pdb:7XNY|rcsb pdb:8G5Y|rcsb pdb:8G5Z|rcsb pdb:8G60|rcsb pdb:8G61|rcsb pdb:8G6J|rcsb pdb:8GLP|rcsb pdb:8IFD|rcsb pdb:8IFE|rcsb pdb:8JDJ|rcsb pdb:8JDK|rcsb pdb:8JDL|rcsb pdb:8JDM|rcsb pdb:8K2C|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPK|rcsb pdb:8PPL|rcsb pdb:8QOI|rcsb pdb:8T4S|rcsb pdb:8XSX|rcsb pdb:8XSY|rcsb pdb:8XSZ|rcsb pdb:8XXL|rcsb pdb:8XXM|rcsb pdb:8XXN|rcsb pdb:8Y0W|rcsb pdb:8Y0X|rcsb pdb:8YOO|rcsb pdb:8YOP|rcsb pdb:9BKD|rcsb pdb:9BLN|rcsb pdb:9G8M|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|dip:DIP-46736N|panther:PTHR19868(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:3++Awu9K48Y1hL1D9TCzw1CepFs1392	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	intact-crc:5D7982C781F0CE44|rigid:yiScs624khiQV9+8wCRtpSW5uB0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P62873	uniprotkb:A0A6H3AE73	intact:EBI-357130|uniprotkb:P04901|uniprotkb:P04697|uniprotkb:B1AJZ7|uniprotkb:Q1RMY8|ensembl:ENSP00000367872.3|ensembl:ENSP00000481878.1|ensembl:ENSP00000515427.1|ensembl:ENSP00000515428.1|ensembl:ENSP00000515429.1|ensembl:ENSP00000515431.1|ensembl:ENSP00000515432.1|ensembl:ENSP00000515433.1|ensembl:ENSP00000515434.1|ensembl:ENSP00000515435.1|ensembl:ENSP00000515436.1|ensembl:ENSP00000515437.1|ensembl:ENSP00000515438.1|ensembl:ENSP00000515440.1|ensembl:ENSP00000515442.1|ensembl:ENSP00000515443.1|ensembl:ENSP00000515444.1|ensembl:ENSP00000515445.1	intact:EBI-2813656|uniprotkb:Q6KVV7|uniprotkb:Q6I221|uniprotkb:E9QQD1|uniprotkb:E9QQD2|uniprotkb:Q81TT6|uniprotkb:A0A1Q4M2S5|uniprotkb:A0A2A8L648	psi-mi:gbb1_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym)	psi-mi:a0a6h3ae73_bacan(display_long)|uniprotkb:GBAA_1174(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833478|imex:IM-13779-3762	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR19850(orthology-group)|dip:DIP-599N|efo:""Orphanet:488613""|ensembl:ENSG00000078369.19(gene)|ensembl:ENST00000378609.9(transcript)|ensembl:ENST00000610897.4(transcript)|ensembl:ENST00000703692.1(transcript)|ensembl:ENST00000703693.1(transcript)|ensembl:ENST00000703694.1(transcript)|ensembl:ENST00000703696.1(transcript)|ensembl:ENST00000703697.1(transcript)|ensembl:ENST00000703699.1(transcript)|ensembl:ENST00000703700.1(transcript)|ensembl:ENST00000703701.1(transcript)|ensembl:ENST00000703702.1(transcript)|ensembl:ENST00000703703.1(transcript)|ensembl:ENST00000703704.1(transcript)|ensembl:ENST00000703706.1(transcript)|ensembl:ENST00000703708.1(transcript)|ensembl:ENST00000703709.1(transcript)|ensembl:ENST00000703710.1(transcript)|ensembl:ENST00000703711.1(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005834""(heterotrimeric G-protein complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007191""(adenylate cyclase-activating dopamine receptor signaling pathway)|go:""GO:0007200""(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:0007213""(G protein-coupled acetylcholine receptor signaling pathway)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0016020""(membrane)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045202""(synapse)|go:""GO:0050909""(sensory perception of taste)|go:""GO:0051020""(GTPase binding)|go:""GO:0060041""(retina development in camera-type eye)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071380""(cellular response to prostaglandin E stimulus)|go:""GO:0071870""(cellular response to catecholamine stimulus)|go:""GO:0097381""(photoreceptor disc membrane)|go:""GO:1903561""(extracellular vesicle)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62873|rcsb pdb:4KFM|rcsb pdb:4PNK|rcsb pdb:5HE0|rcsb pdb:5HE1|rcsb pdb:5HE2|rcsb pdb:5HE3|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UKM|rcsb pdb:5UZ7|rcsb pdb:6B3J|rcsb pdb:6CRK|rcsb pdb:6D9H|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6E3Y|rcsb pdb:6EG8|rcsb pdb:6G79|rcsb pdb:6GDG|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6M8S|rcsb pdb:6N4B|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6OIJ|rcsb pdb:6OIK|rcsb pdb:6OMM|rcsb pdb:6ORV|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VMS|rcsb pdb:6VN7|rcsb pdb:6WHA|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:6XOX|rcsb pdb:7AUE|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7D76|rcsb pdb:7D77|rcsb pdb:7D7M|rcsb pdb:7DB6|rcsb pdb:7DFL|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7E9H|rcsb pdb:7EB2|rcsb pdb:7EJ0|rcsb pdb:7EJ8|rcsb pdb:7EJA|rcsb pdb:7EJK|rcsb pdb:7EJX|rcsb pdb:7EO2|rcsb pdb:7EO4|rcsb pdb:7EPT|rcsb pdb:7EUO|rcsb pdb:7EVY|rcsb pdb:7EVZ|rcsb pdb:7EW0|rcsb pdb:7EW1|rcsb pdb:7EW2|rcsb pdb:7EW3|rcsb pdb:7EW4|rcsb pdb:7EW7|rcsb pdb:7EXD|rcsb pdb:7EZH|rcsb pdb:7EZK|rcsb pdb:7EZM|rcsb pdb:7F0T|rcsb pdb:7F1O|rcsb pdb:7F1Q|rcsb pdb:7F1R|rcsb pdb:7F1S|rcsb pdb:7F1Z|rcsb pdb:7F23|rcsb pdb:7F24|rcsb pdb:7F4D|rcsb pdb:7F4F|rcsb pdb:7F4H|rcsb pdb:7F4I|rcsb pdb:7F53|rcsb pdb:7F54|rcsb pdb:7F55|rcsb pdb:7F58|rcsb pdb:7F6G|rcsb pdb:7F6H|rcsb pdb:7F6I|rcsb pdb:7F8V|rcsb pdb:7F8W|rcsb pdb:7F9Y|rcsb pdb:7F9Z|rcsb pdb:7JHJ|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7JVR|rcsb pdb:7K7L|rcsb pdb:7K7Z|rcsb pdb:7KH0|rcsb pdb:7KI0|rcsb pdb:7KI1|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7L1U|rcsb pdb:7L1V|rcsb pdb:7LCI|rcsb pdb:7LD3|rcsb pdb:7LD4|rcsb pdb:7LLL|rcsb pdb:7LLY|rcsb pdb:7MTS|rcsb pdb:7NA7|rcsb pdb:7NA8|rcsb pdb:7P00|rcsb pdb:7P02|rcsb pdb:7QVM|rcsb pdb:7RA3|rcsb pdb:7RAN|rcsb pdb:7RBT|rcsb pdb:7RG9|rcsb pdb:7RGP|rcsb pdb:7RKF|rcsb pdb:7RKM|rcsb pdb:7RKN|rcsb pdb:7RKX|rcsb pdb:7RKY|rcsb pdb:7RMG|rcsb pdb:7RMH|rcsb pdb:7RMI|rcsb pdb:7RTB|rcsb pdb:7RYC|rcsb pdb:7S1M|rcsb pdb:7S3I|rcsb pdb:7S8L|rcsb pdb:7S8M|rcsb pdb:7S8N|rcsb pdb:7S8O|rcsb pdb:7S8P|rcsb pdb:7SBF|rcsb pdb:7SCG|rcsb pdb:7SF7|rcsb pdb:7SF8|rcsb pdb:7SR8|rcsb pdb:7SRR|rcsb pdb:7T10|rcsb pdb:7T11|rcsb pdb:7T2G|rcsb pdb:7T2H|rcsb pdb:7T6B|rcsb pdb:7T8X|rcsb pdb:7T90|rcsb pdb:7T94|rcsb pdb:7T96|rcsb pdb:7T9I|rcsb pdb:7T9N|rcsb pdb:7TMW|rcsb pdb:7TRK|rcsb pdb:7TRP|rcsb pdb:7TRQ|rcsb pdb:7TRS|rcsb pdb:7TUZ|rcsb pdb:7TYF|rcsb pdb:7TYH|rcsb pdb:7TYI|rcsb pdb:7TYL|rcsb pdb:7TYN|rcsb pdb:7TYO|rcsb pdb:7TYW|rcsb pdb:7TYX|rcsb pdb:7TYY|rcsb pdb:7TZF|rcsb pdb:7U2K|rcsb pdb:7U2L|rcsb pdb:7UM5|rcsb pdb:7UM6|rcsb pdb:7UM7|rcsb pdb:7UTZ|rcsb pdb:7V68|rcsb pdb:7V69|rcsb pdb:7V6A|rcsb pdb:7VDH|rcsb pdb:7VDL|rcsb pdb:7VDM|rcsb pdb:7VFX|rcsb pdb:7VGX|rcsb pdb:7VIE|rcsb pdb:7VIF|rcsb pdb:7VIG|rcsb pdb:7VIH|rcsb pdb:7VKT|rcsb pdb:7VL8|rcsb pdb:7VL9|rcsb pdb:7VLA|rcsb pdb:7VUG|rcsb pdb:7VUH|rcsb pdb:7VUI|rcsb pdb:7VUJ|rcsb pdb:7VUY|rcsb pdb:7VUZ|rcsb pdb:7VV3|rcsb pdb:7VV5|rcsb pdb:7W0L|rcsb pdb:7W0M|rcsb pdb:7W0N|rcsb pdb:7W0O|rcsb pdb:7W0P|rcsb pdb:7W2Z|rcsb pdb:7W3Z|rcsb pdb:7W40|rcsb pdb:7XBW|rcsb pdb:7W53|rcsb pdb:7W55|rcsb pdb:7W56|rcsb pdb:7W57|rcsb pdb:7W6P|rcsb pdb:7W7E|rcsb pdb:7WCM|rcsb pdb:7WCN|rcsb pdb:7WF7|rcsb pdb:7WJ5|rcsb pdb:7WKD|rcsb pdb:7WU2|rcsb pdb:7WU3|rcsb pdb:7WU4|rcsb pdb:7WU5|rcsb pdb:7WU9|rcsb pdb:7WUI|rcsb pdb:7WUJ|rcsb pdb:7WUQ|rcsb pdb:7WV9|rcsb pdb:7WVU|rcsb pdb:7WVV|rcsb pdb:7WVW|rcsb pdb:7WVX|rcsb pdb:7WVY|rcsb pdb:7WXU|rcsb pdb:7WXW|rcsb pdb:7WY0|rcsb pdb:7WY5|rcsb pdb:7WY8|rcsb pdb:7WYB|rcsb pdb:7WZ4|rcsb pdb:7WZ7|rcsb pdb:7X10|rcsb pdb:7X2C|rcsb pdb:7X2D|rcsb pdb:7X2F|rcsb pdb:7X2V|rcsb pdb:7X5H|rcsb pdb:7X9A|rcsb pdb:7X9B|rcsb pdb:7X9C|rcsb pdb:7X9Y|rcsb pdb:7XA3|rcsb pdb:7XBD|rcsb pdb:7XBX|rcsb pdb:7XJJ|rcsb pdb:7XJK|rcsb pdb:7XJL|rcsb pdb:7XK2|rcsb pdb:7XK8|rcsb pdb:7XKD|rcsb pdb:7XKE|rcsb pdb:7XKF|rcsb pdb:7XMR|rcsb pdb:7XMS|rcsb pdb:7XMT|rcsb pdb:7XOU|rcsb pdb:7XOV|rcsb pdb:7XOW|rcsb pdb:7XP4|rcsb pdb:7XP5|rcsb pdb:7XP6|rcsb pdb:7XT8|rcsb pdb:7XT9|rcsb pdb:7XTA|rcsb pdb:7XTB|rcsb pdb:7XTC|rcsb pdb:7XTQ|rcsb pdb:7XV3|rcsb pdb:7XW5|rcsb pdb:7XW6|rcsb pdb:7XXH|rcsb pdb:7XXI|rcsb pdb:7XY6|rcsb pdb:7XY7|rcsb pdb:7XZ5|rcsb pdb:7XZ6|rcsb pdb:7Y1F|rcsb pdb:7Y24|rcsb pdb:7Y26|rcsb pdb:7Y27|rcsb pdb:7Y3G|rcsb pdb:7Y64|rcsb pdb:7Y65|rcsb pdb:7Y66|rcsb pdb:7Y67|rcsb pdb:7Y89|rcsb pdb:7YAC|rcsb pdb:7YAE|rcsb pdb:7YDH|rcsb pdb:7YDJ|rcsb pdb:7YDM|rcsb pdb:7YDP|rcsb pdb:7YFC|rcsb pdb:7YFD|rcsb pdb:7YK6|rcsb pdb:7YK7|rcsb pdb:7YKD|rcsb pdb:7YON|rcsb pdb:7YOO|rcsb pdb:7YP7|rcsb pdb:7YS6|rcsb pdb:8DDW|rcsb pdb:8DDX|rcsb pdb:8DPF|rcsb pdb:8DPG|rcsb pdb:8DPH|rcsb pdb:8DPI|rcsb pdb:8DWC|rcsb pdb:8DWG|rcsb pdb:8DWH|rcsb pdb:8DZP|rcsb pdb:8DZQ|rcsb pdb:8DZR|rcsb pdb:8DZS|rcsb pdb:8E3X|rcsb pdb:8E3Y|rcsb pdb:8E3Z|rcsb pdb:8E9W|rcsb pdb:8E9X|rcsb pdb:8E9Y|rcsb pdb:8E9Z|rcsb pdb:8EIT|rcsb pdb:8EJC|rcsb pdb:8EJK|rcsb pdb:8EMW|rcsb pdb:8EMX|rcsb pdb:8F0J|rcsb pdb:8F0K|rcsb pdb:8F2A|rcsb pdb:8F2B|rcsb pdb:8F76|rcsb pdb:8FEG|rcsb pdb:8FLQ|rcsb pdb:8FLR|rcsb pdb:8FLS|rcsb pdb:8FLT|rcsb pdb:8FLU|rcsb pdb:8FMZ|rcsb pdb:8FN0|rcsb pdb:8FN1|rcsb pdb:8FU6|rcsb pdb:8FX5|rcsb pdb:8FY8|rcsb pdb:8FYE|rcsb pdb:8FYL|rcsb pdb:8FYT|rcsb pdb:8FYX|rcsb pdb:8G05|rcsb pdb:8G2Y|rcsb pdb:8G59|rcsb pdb:8G94|rcsb pdb:8GAG|rcsb pdb:8GCM|rcsb pdb:8GCP|rcsb pdb:8GD9|rcsb pdb:8GDA|rcsb pdb:8GDB|rcsb pdb:8GDC|rcsb pdb:8GDZ|rcsb pdb:8GE1|rcsb pdb:8GE2|rcsb pdb:8GE3|rcsb pdb:8GE4|rcsb pdb:8GE5|rcsb pdb:8GE6|rcsb pdb:8GE7|rcsb pdb:8GE8|rcsb pdb:8GE9|rcsb pdb:8GEA|rcsb pdb:8GEB|rcsb pdb:8GEC|rcsb pdb:8GED|rcsb pdb:8GEE|rcsb pdb:8GEF|rcsb pdb:8GEG|rcsb pdb:8GEH|rcsb pdb:8GEI|rcsb pdb:8GEJ|rcsb pdb:8GFV|rcsb pdb:8GFW|rcsb pdb:8GFX|rcsb pdb:8GFY|rcsb pdb:8GFZ|rcsb pdb:8GG0|rcsb pdb:8GG1|rcsb pdb:8GG2|rcsb pdb:8GG3|rcsb pdb:8GG4|rcsb pdb:8GG5|rcsb pdb:8GG6|rcsb pdb:8GG7|rcsb pdb:8GG8|rcsb pdb:8GG9|rcsb pdb:8GGA|rcsb pdb:8GGB|rcsb pdb:8GGC|rcsb pdb:8GGE|rcsb pdb:8GGF|rcsb pdb:8GHV|rcsb pdb:8GUQ|rcsb pdb:8GUR|rcsb pdb:8GUS|rcsb pdb:8GUT|rcsb pdb:8GY7|rcsb pdb:8H0P|rcsb pdb:8H0Q|rcsb pdb:8H2G|rcsb pdb:8H4I|rcsb pdb:8H4K|rcsb pdb:8H4L|rcsb pdb:8H8J|rcsb pdb:8HBD|rcsb pdb:8HCQ|rcsb pdb:8HCX|rcsb pdb:8HDO|rcsb pdb:8HDP|rcsb pdb:8HIX|rcsb pdb:8HJ0|rcsb pdb:8HJ1|rcsb pdb:8HJ2|rcsb pdb:8HJ5|rcsb pdb:8HMP|rcsb pdb:8HMV|rcsb pdb:8HN8|rcsb pdb:8HNK|rcsb pdb:8HNL|rcsb pdb:8HNM|rcsb pdb:8HOC|rcsb pdb:8HPT|rcsb pdb:8HQC|rcsb pdb:8HQE|rcsb pdb:8HQM|rcsb pdb:8HQN|rcsb pdb:8HS3|rcsb pdb:8HSC|rcsb pdb:8HTI|rcsb pdb:8HVI|rcsb pdb:8I2G|rcsb pdb:8I7V|rcsb pdb:8I7W|rcsb pdb:8I95|rcsb pdb:8I97|rcsb pdb:8I9A|rcsb pdb:8I9L|rcsb pdb:8I9S|rcsb pdb:8IA2|rcsb pdb:8IA7|rcsb pdb:8IA8|rcsb pdb:8IBU|rcsb pdb:8IBV|rcsb pdb:8IC0|rcsb pdb:8ID3|rcsb pdb:8ID4|rcsb pdb:8ID6|rcsb pdb:8ID8|rcsb pdb:8ID9|rcsb pdb:8IEC|rcsb pdb:8IED|rcsb pdb:8IJ3|rcsb pdb:8IJA|rcsb pdb:8IJB|rcsb pdb:8IJD|rcsb pdb:8IKG|rcsb pdb:8IKH|rcsb pdb:8IKL|rcsb pdb:8INR|rcsb pdb:8IOC|rcsb pdb:8IOD|rcsb pdb:8IQ4|rcsb pdb:8IQ6|rcsb pdb:8IRR|rcsb pdb:8IRS|rcsb pdb:8IRT|rcsb pdb:8IRU|rcsb pdb:8IRV|rcsb pdb:8ITF|rcsb pdb:8IU2|rcsb pdb:8IUK|rcsb pdb:8IUL|rcsb pdb:8IUM|rcsb pdb:8IW1|rcsb pdb:8IW4|rcsb pdb:8IW7|rcsb pdb:8IW9|rcsb pdb:8IY9|rcsb pdb:8IYH|rcsb pdb:8IYS|rcsb pdb:8IYW|rcsb pdb:8IZ4|rcsb pdb:8IZB|rcsb pdb:8J18|rcsb pdb:8J19|rcsb pdb:8J1A|rcsb pdb:8J20|rcsb pdb:8J21|rcsb pdb:8J22|rcsb pdb:8J23|rcsb pdb:8J24|rcsb pdb:8J6D|rcsb pdb:8J6I|rcsb pdb:8J6J|rcsb pdb:8J6L|rcsb pdb:8J6P|rcsb pdb:8J6Q|rcsb pdb:8J6R|rcsb pdb:8J9N|rcsb pdb:8JD3|rcsb pdb:8JD5|rcsb pdb:8JD6|rcsb pdb:8JER|rcsb pdb:8JGB|rcsb pdb:8JGF|rcsb pdb:8JGG|rcsb pdb:8JHB|rcsb pdb:8JHI|rcsb pdb:8JHN|rcsb pdb:8JHY|rcsb pdb:8JII|rcsb pdb:8JIL|rcsb pdb:8JIM|rcsb pdb:8JJP|rcsb pdb:8JKB|rcsb pdb:8JLJ|rcsb pdb:8JLK|rcsb pdb:8JLN|rcsb pdb:8JLO|rcsb pdb:8JLP|rcsb pdb:8JLQ|rcsb pdb:8JLR|rcsb pdb:8JLZ|rcsb pdb:8JPN|rcsb pdb:8JPP|rcsb pdb:8JR9|rcsb pdb:8JSO|rcsb pdb:8JSP|rcsb pdb:8JT6|rcsb pdb:8JXT|rcsb pdb:8JXV|rcsb pdb:8JXW|rcsb pdb:8JXX|rcsb pdb:8JZ7|rcsb pdb:8JZZ|rcsb pdb:8K2X|rcsb pdb:8K3Z|rcsb pdb:8K4N|rcsb pdb:8K4O|rcsb pdb:8K4P|rcsb pdb:8K6M|rcsb pdb:8K6N|rcsb pdb:8K6O|rcsb pdb:8K8J|rcsb pdb:8K9K|rcsb pdb:8K9L|rcsb pdb:8KFX|rcsb pdb:8KFY|rcsb pdb:8KFZ|rcsb pdb:8KGG|rcsb pdb:8KGK|rcsb pdb:8KH4|rcsb pdb:8KH5|rcsb pdb:8PJK|rcsb pdb:8PKM|rcsb pdb:8PM2|rcsb pdb:8POK|rcsb pdb:8QJ2|rcsb pdb:8SAI|rcsb pdb:8SG1|rcsb pdb:8SL3|rcsb pdb:8SMV|rcsb pdb:8SZG|rcsb pdb:8SZH|rcsb pdb:8SZI|rcsb pdb:8T3O|rcsb pdb:8T3Q|rcsb pdb:8T3S|rcsb pdb:8T3V|rcsb pdb:8TB0|rcsb pdb:8THK|rcsb pdb:8THL|rcsb pdb:8TZQ|rcsb pdb:8U02|rcsb pdb:8U1U|rcsb pdb:8U26|rcsb pdb:8U4N|rcsb pdb:8U4O|rcsb pdb:8U4P|rcsb pdb:8U4Q|rcsb pdb:8U7Z|rcsb pdb:8U81|rcsb pdb:8U82|rcsb pdb:8U83|rcsb pdb:8U84|rcsb pdb:8U8F|rcsb pdb:8UGY|rcsb pdb:8UH3|rcsb pdb:8UHB|rcsb pdb:8UNL|rcsb pdb:8UNM|rcsb pdb:8UNN|rcsb pdb:8UNO|rcsb pdb:8UNP|rcsb pdb:8UNQ|rcsb pdb:8UNR|rcsb pdb:8UNS|rcsb pdb:8UNT|rcsb pdb:8UNU|rcsb pdb:8UNV|rcsb pdb:8UNW|rcsb pdb:8UNX|rcsb pdb:8UNY|rcsb pdb:8UNZ|rcsb pdb:8UO0|rcsb pdb:8UO1|rcsb pdb:8UO2|rcsb pdb:8UO3|rcsb pdb:8UO4|rcsb pdb:8UQO|rcsb pdb:8UWL|rcsb pdb:8V6U|rcsb pdb:8VY7|rcsb pdb:8VY9|rcsb pdb:8W87|rcsb pdb:8W88|rcsb pdb:8W89|rcsb pdb:8W8A|rcsb pdb:8W8B|rcsb pdb:8W8Q|rcsb pdb:8W8R|rcsb pdb:8WC3|rcsb pdb:8WC4|rcsb pdb:8WC5|rcsb pdb:8WC6|rcsb pdb:8WC7|rcsb pdb:8WC8|rcsb pdb:8WC9|rcsb pdb:8WCA|rcsb pdb:8WCB|rcsb pdb:8WJX|rcsb pdb:8WOG|rcsb pdb:8WP1|rcsb pdb:8WPU|rcsb pdb:8WRB|rcsb pdb:8WSS|rcsb pdb:8WST|rcsb pdb:8WW2|rcsb pdb:8X2K|rcsb pdb:8X79|rcsb pdb:8X7A|rcsb pdb:8X8L|rcsb pdb:8X8N|rcsb pdb:8XGM|rcsb pdb:8XIO|rcsb pdb:8XIP|rcsb pdb:8XIQ|rcsb pdb:8XIR|rcsb pdb:8XJK|rcsb pdb:8XJL|rcsb pdb:8XJM|rcsb pdb:8XJN|rcsb pdb:8XJO|rcsb pdb:8XOF|rcsb pdb:8XOG|rcsb pdb:8XOH|rcsb pdb:8XOI|rcsb pdb:8XOJ|rcsb pdb:8XQL|rcsb pdb:8XQN|rcsb pdb:8XQO|rcsb pdb:8XQP|rcsb pdb:8XQR|rcsb pdb:8XQS|rcsb pdb:8XQT|rcsb pdb:8XVE|rcsb pdb:8XVH|rcsb pdb:8XVI|rcsb pdb:8XWP|rcsb pdb:8XWQ|rcsb pdb:8XZF|rcsb pdb:8XZG|rcsb pdb:8XZH|rcsb pdb:8XZI|rcsb pdb:8XZJ|rcsb pdb:8Y52|rcsb pdb:8Y53|rcsb pdb:8YKY|rcsb pdb:8YN2|rcsb pdb:8YN3|rcsb pdb:8YN4|rcsb pdb:8YN5|rcsb pdb:8YN6|rcsb pdb:8YN9|rcsb pdb:8YNA|rcsb pdb:8YRG|rcsb pdb:8YUT|rcsb pdb:8YUU|rcsb pdb:8YUV|rcsb pdb:8YW3|rcsb pdb:8YW4|rcsb pdb:8YW5|rcsb pdb:8YY8|rcsb pdb:8ZFJ|rcsb pdb:8ZJD|rcsb pdb:8ZJE|rcsb pdb:8ZPS|rcsb pdb:8ZPT|rcsb pdb:8ZQE|rcsb pdb:8ZR5|rcsb pdb:8ZRK|rcsb pdb:8ZSJ|rcsb pdb:8ZSP|rcsb pdb:8ZSS|rcsb pdb:8ZSV|rcsb pdb:9ASB|rcsb pdb:9AUC|rcsb pdb:9AVG|rcsb pdb:9AXF|rcsb pdb:9AYF|rcsb pdb:9BKJ|rcsb pdb:9BKK|rcsb pdb:9BQJ|rcsb pdb:9EPP|rcsb pdb:9EPQ|rcsb pdb:9ERX|rcsb pdb:9EW2|rcsb pdb:9GYO|rcsb pdb:9IIX|rcsb pdb:9IJ9|rcsb pdb:9IQT|rcsb pdb:9JKQ|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-381676|reactome:R-HSA-381753|reactome:R-HSA-381771|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9634597|reactome:R-HSA-9660821|reactome:R-HSA-9717207|reactome:R-HSA-9856530|reactome:R-HSA-997272|refseq:NP_001269467.1|refseq:NP_001269468.1|refseq:NP_002065.1|refseq:XP_016856548.1|refseq:XP_016856549.1|refseq:XP_016856550.1"	"interpro:IPR023214|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR000150(Cof protein)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0016791""(phosphatase activity)|refseq:WP_001041235.1|interpro:IPR036412"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk9606	rogid:RyvWr3a71dNOyF+97bhJSz4wZNY1392	intact-crc:B676085E9B66CAE8|rigid:/u1E5XXwT4QfFC/T82bHx/v76pU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H2Q9	uniprotkb:P50440	intact:EBI-2810400|uniprotkb:Q6KTQ9|uniprotkb:Q6HZS4|uniprotkb:E9RAZ3|uniprotkb:E9RAZ4|uniprotkb:Q81RJ7|uniprotkb:A0A0F7RD30	intact:EBI-2552594|uniprotkb:Q53EQ4|uniprotkb:B4DH99|uniprotkb:B4DPI3|ensembl:ENSP00000379895.3	psi-mi:a0a6l7h2q9_bacan(display_long)|uniprotkb:GBAA_2047(locus name)	"psi-mi:gatm_human(display_long)|uniprotkb:AGAT(gene name synonym)|uniprotkb:""L-arginine:glycine amidinotransferase""(gene name synonym)|uniprotkb:Transamidinase(gene name synonym)|uniprotkb:GATM(gene name)|psi-mi:GATM(display_short)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833485|imex:IM-13779-3764	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|refseq:WP_000216920.1	"ensembl:ENSG00000171766.17(gene)|ensembl:ENST00000396659.8(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006600""(creatine metabolic process)|go:""GO:0006601""(creatine biosynthetic process)|go:""GO:0007611""(learning or memory)|go:""GO:0014889""(muscle atrophy)|go:""GO:0015067""(amidinotransferase activity)|go:""GO:0015068""(glycine amidinotransferase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|interpro:IPR033195|rcsb pdb:1JDW|rcsb pdb:1JDX|rcsb pdb:2JDW|rcsb pdb:2JDX|rcsb pdb:3JDW|rcsb pdb:4JDW|rcsb pdb:5JDW|rcsb pdb:6JDW|rcsb pdb:7JDW|rcsb pdb:8JDW|rcsb pdb:9JDW|reactome:R-HSA-71288|refseq:NP_001473.1|efo:""Orphanet:3337""|efo:""Orphanet:35704""|panther:PTHR10488(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H+yb15aOHMi9sIfuMqerdtx927Y1392	rogid:FYkmOSpHilJ5gCuPd5PQ3dIQiy89606	intact-crc:27C0408CE0DF6F8B|rigid:ZxJJZV4a5OsbzZ7ipFvIvzyWV28	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50440	uniprotkb:Q81R83	intact:EBI-2552594|uniprotkb:Q53EQ4|uniprotkb:B4DH99|uniprotkb:B4DPI3|ensembl:ENSP00000379895.3	intact:EBI-2810574|uniprotkb:Q6KTE5|uniprotkb:Q6HZF6	"psi-mi:gatm_human(display_long)|uniprotkb:AGAT(gene name synonym)|uniprotkb:""L-arginine:glycine amidinotransferase""(gene name synonym)|uniprotkb:Transamidinase(gene name synonym)|uniprotkb:GATM(gene name)|psi-mi:GATM(display_short)"	psi-mi:y2173_bacan(display_long)|uniprotkb:BA_2173(locus name)|uniprotkb:GBAA_2173(locus name)|uniprotkb:BAS2019(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833499|imex:IM-13779-3765	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000171766.17(gene)|ensembl:ENST00000396659.8(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006600""(creatine metabolic process)|go:""GO:0006601""(creatine biosynthetic process)|go:""GO:0007611""(learning or memory)|go:""GO:0014889""(muscle atrophy)|go:""GO:0015067""(amidinotransferase activity)|go:""GO:0015068""(glycine amidinotransferase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|interpro:IPR033195|rcsb pdb:1JDW|rcsb pdb:1JDX|rcsb pdb:2JDW|rcsb pdb:2JDX|rcsb pdb:3JDW|rcsb pdb:4JDW|rcsb pdb:5JDW|rcsb pdb:6JDW|rcsb pdb:7JDW|rcsb pdb:8JDW|rcsb pdb:9JDW|reactome:R-HSA-71288|refseq:NP_001473.1|efo:""Orphanet:3337""|efo:""Orphanet:35704""|panther:PTHR10488(orthology-group)"	"interpro:IPR009474(Protein of unknown function DUF1094)|go:""GO:0045454""(cell redox homeostasis)|refseq:WP_000063712.1|refseq:NP_844566.1|refseq:YP_028282.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FYkmOSpHilJ5gCuPd5PQ3dIQiy89606	rogid:DwG1RQbAdj088ZOY9O74UrEBXms1392	intact-crc:491967A823E366E7|rigid:8MgD9/H8d/T+UL8RhlJw8EcApVo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HG24	uniprotkb:P50440	intact:EBI-2811385|uniprotkb:Q6KMQ6|uniprotkb:Q6HTG4|uniprotkb:E9R169|uniprotkb:E9R170|uniprotkb:Q81M11|uniprotkb:A0A0F7R8D9	intact:EBI-2552594|uniprotkb:Q53EQ4|uniprotkb:B4DH99|uniprotkb:B4DPI3|ensembl:ENSP00000379895.3	psi-mi:a0a6l7hg24_bacan(display_long)|uniprotkb:GBAA_4444(locus name)	"psi-mi:gatm_human(display_long)|uniprotkb:AGAT(gene name synonym)|uniprotkb:""L-arginine:glycine amidinotransferase""(gene name synonym)|uniprotkb:Transamidinase(gene name synonym)|uniprotkb:GATM(gene name)|psi-mi:GATM(display_short)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833492|imex:IM-13779-3767	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR051782|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000891288.1"	"ensembl:ENSG00000171766.17(gene)|ensembl:ENST00000396659.8(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005758""(mitochondrial intermembrane space)|go:""GO:0006600""(creatine metabolic process)|go:""GO:0006601""(creatine biosynthetic process)|go:""GO:0007611""(learning or memory)|go:""GO:0014889""(muscle atrophy)|go:""GO:0015067""(amidinotransferase activity)|go:""GO:0015068""(glycine amidinotransferase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|interpro:IPR033195|rcsb pdb:1JDW|rcsb pdb:1JDX|rcsb pdb:2JDW|rcsb pdb:2JDX|rcsb pdb:3JDW|rcsb pdb:4JDW|rcsb pdb:5JDW|rcsb pdb:6JDW|rcsb pdb:7JDW|rcsb pdb:8JDW|rcsb pdb:9JDW|reactome:R-HSA-71288|refseq:NP_001473.1|efo:""Orphanet:3337""|efo:""Orphanet:35704""|panther:PTHR10488(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/pw+ThQWZ4LMdrZ7n9sAVSfc+v41392	rogid:FYkmOSpHilJ5gCuPd5PQ3dIQiy89606	intact-crc:88F76BA54026353D|rigid:4+J73eKa/o5bEwVkrLQK5vQj7NE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UN86	uniprotkb:A0A6L8PT45	intact:EBI-1044298|uniprotkb:O60606|uniprotkb:O75149|uniprotkb:Q9UPA1|uniprotkb:A8K6X1|ensembl:ENSP00000352738.4|ensembl:ENSP00000379069.3|ensembl:ENSP00000503228.1|ensembl:ENSP00000503239.1|ensembl:ENSP00000503355.1|ensembl:ENSP00000503504.1|ensembl:ENSP00000503669.1|ensembl:ENSP00000503911.1|ensembl:ENSP00000503943.1|ensembl:ENSP00000504101.1|ensembl:ENSP00000504159.1|ensembl:ENSP00000504316.1|ensembl:ENSP00000504361.1|ensembl:ENSP00000504371.1|ensembl:ENSP00000504496.1|ensembl:ENSP00000504523.1|ensembl:ENSP00000504585.1|ensembl:ENSP00000504698.1|intact:EBI-21356833	intact:EBI-2825742|uniprotkb:Q6KVF1|uniprotkb:Q6I1K2|uniprotkb:E9RAT2|uniprotkb:E9RAT3|uniprotkb:Q81TC5|uniprotkb:A0A0J1HZ85	psi-mi:g3bp2_human(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3BP2(gene name)|psi-mi:G3BP2(display_short)|uniprotkb:KIAA0660(gene name synonym)	psi-mi:a0a6l8pt45_bacan(display_long)|uniprotkb:queE(gene name)|psi-mi:queE(display_short)|uniprotkb:Queuosine biosynthesis protein QueE(gene name synonym)|uniprotkb:GBAA_1361(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833513|imex:IM-13779-3768	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036429.2|refseq:NP_987100.1|refseq:NP_987101.1|refseq:XP_005263439.1|refseq:XP_005263440.1|refseq:XP_011530743.1|refseq:XP_016864365.1|refseq:XP_016864366.1|refseq:XP_016864367.1|refseq:XP_016864368.1|dip:DIP-50299N|ensembl:ENSG00000138757.15(gene)|ensembl:ENST00000359707.9(transcript)|ensembl:ENST00000395719.7(transcript)|ensembl:ENST00000676584.1(transcript)|ensembl:ENST00000676974.1(transcript)|ensembl:ENST00000677162.1(transcript)|ensembl:ENST00000677171.1(transcript)|ensembl:ENST00000677201.1(transcript)|ensembl:ENST00000677333.1(transcript)|ensembl:ENST00000677566.1(transcript)|ensembl:ENST00000677606.1(transcript)|ensembl:ENST00000677620.1(transcript)|ensembl:ENST00000678062.1(transcript)|ensembl:ENST00000678100.1(transcript)|ensembl:ENST00000678123.1(transcript)|ensembl:ENST00000678265.1(transcript)|ensembl:ENST00000678578.1(transcript)|ensembl:ENST00000678798.1(transcript)|ensembl:ENST00000678971.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007253""(obsolete cytoplasmic sequestering of NF-kappaB)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0034063""(stress granule assembly)|go:""GO:0045087""(innate immune response)|go:""GO:0051028""(mRNA transport)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0140693""(molecular condensate scaffold activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR035979|interpro:IPR039539|mint:Q9UN86|rcsb pdb:5DRV|reactome:R-HSA-9705671|panther:PTHR10693(orthology-group)"	"interpro:IPR017742(""7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE"")|interpro:IPR007197(Radical SAM)|interpro:IPR024924|go:""GO:0000287""(magnesium ion binding)|go:""GO:0008616""(queuosine biosynthetic process)|go:""GO:0016840""(carbon-nitrogen lyase activity)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:1904047""(S-adenosyl-L-methionine binding)|refseq:WP_000036288.1|interpro:IPR013785(Aldolase-type TIM barrel)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:bYP8U2wviIqJBWcnLQnuoV0MhV89606	rogid:gTku1wUCCSbVrsy9wG9sItVGxNc1392	intact-crc:60E5C0AFF97B5994|rigid:qL59U0Sx6OF86if7jrOQuGhMyPk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HFV2	uniprotkb:O60861	intact:EBI-2818324|uniprotkb:Q6KPE6|uniprotkb:Q6HV74|uniprotkb:E9QVT9|uniprotkb:E9QVU0|uniprotkb:Q81XX7|uniprotkb:A0A0F7RA63	intact:EBI-2683717|uniprotkb:Q53Y77|uniprotkb:B2RCK9|uniprotkb:Q7Z571|uniprotkb:O43144|uniprotkb:A8KAC2|ensembl:ENSP00000407552.2	psi-mi:a0a6l7hfv2_bacan(display_long)|uniprotkb:GBAA_3787(locus name)	psi-mi:gas7_human(display_long)|uniprotkb:KIAA0394(gene name synonym)|uniprotkb:GAS7(gene name)|psi-mi:GAS7(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833506|imex:IM-13779-3766	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR027417|interpro:IPR005021(Phage Terminase)|go:""GO:0004519""(endonuclease activity)|refseq:WP_001222618.1|interpro:IPR046461|interpro:IPR046462"	"refseq:XP_011522346.1|refseq:NP_003635.2|refseq:NP_958836.1|refseq:NP_958839.1|refseq:NP_001124303.1|refseq:XP_005256888.1|refseq:XP_005256889.1|refseq:XP_016880728.1|ensembl:ENSG00000007237.19(gene)|ensembl:ENST00000432992.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0030041""(actin filament polymerization)|go:""GO:0042802""(identical protein binding)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051015""(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036020|interpro:IPR036028|interpro:IPR037957|mint:O60861|rcsb pdb:2LX7|rcsb pdb:2YSH|panther:PTHR23065(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iK417DPiQ3Ypjwn5KZjvXuIzx2M1392	rogid:AGTjGZ7Nb4FN05kKzZ7POn5n+xQ9606	intact-crc:E7759EE8F161C58D|rigid:K8DJyhTnYCYEnsuT8231NvIJzaA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81TN2	uniprotkb:O15117	intact:EBI-2833534|uniprotkb:Q6KVQ4|uniprotkb:E9R534	intact:EBI-1753267|uniprotkb:O00359|uniprotkb:A8K2Y8|uniprotkb:E9PBV9|uniprotkb:Q9NZI9|uniprotkb:B4DLN2|ensembl:ENSP00000316460.7|ensembl:ENSP00000426346.1	psi-mi:q81tn2_bacan(display_long)|uniprotkb:GBAA_1239(locus name)	psi-mi:fyb1_human(display_long)|uniprotkb:FYB1(gene name)|psi-mi:FYB1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLAP130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833538|imex:IM-13779-3772	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0000725""(recombinational repair)|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0033202""(DNA helicase complex)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR027417|interpro:IPR013986(DNA helicase, DEXX box type)"	"dip:DIP-42204N|efo:""Orphanet:566192""|ensembl:ENSG00000082074.19(gene)|ensembl:ENST00000351578.12(transcript)|ensembl:ENST00000515010.5(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008289""(lipid binding)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0032991""(protein-containing complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0070161""(anchoring junction)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|mint:O15117|rcsb pdb:1RI9|rcsb pdb:2GTJ|rcsb pdb:2GTO|reactome:R-HSA-202433|reactome:R-HSA-391160|refseq:NP_001230022.1|refseq:NP_001456.3|refseq:NP_955367.1|refseq:XP_006714527.1|refseq:XP_006714528.1|refseq:XP_006714529.1|refseq:XP_011512310.1|refseq:XP_011512311.1|refseq:XP_011512312.1|panther:PTHR16830(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:65XbQgYfJ5iGwomK1u3WBt3UPjs1392	rogid:ObeGCVefTolMBQGVT/WhglH5F009606	intact-crc:0F1F912200601810|rigid:gl3WS+PJJCkujDi861wuvhFl9zs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UN86	uniprotkb:Q81L32	intact:EBI-1044298|uniprotkb:O60606|uniprotkb:O75149|uniprotkb:Q9UPA1|uniprotkb:A8K6X1|ensembl:ENSP00000352738.4|ensembl:ENSP00000379069.3|ensembl:ENSP00000503228.1|ensembl:ENSP00000503239.1|ensembl:ENSP00000503355.1|ensembl:ENSP00000503504.1|ensembl:ENSP00000503669.1|ensembl:ENSP00000503911.1|ensembl:ENSP00000503943.1|ensembl:ENSP00000504101.1|ensembl:ENSP00000504159.1|ensembl:ENSP00000504316.1|ensembl:ENSP00000504361.1|ensembl:ENSP00000504371.1|ensembl:ENSP00000504496.1|ensembl:ENSP00000504523.1|ensembl:ENSP00000504585.1|ensembl:ENSP00000504698.1|intact:EBI-21356833	intact:EBI-2810244|uniprotkb:Q6HSI7|uniprotkb:Q6KLT2	psi-mi:g3bp2_human(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3BP2(gene name)|psi-mi:G3BP2(display_short)|uniprotkb:KIAA0660(gene name synonym)	psi-mi:syn_bacan(display_long)|uniprotkb:asnS(gene name)|psi-mi:asnS(display_short)|uniprotkb:Asparaginyl-tRNA synthetase(gene name synonym)|uniprotkb:BAS4454(locus name)|uniprotkb:BA_4802(locus name)|uniprotkb:GBAA_4802(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833527|imex:IM-13779-3769	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036429.2|refseq:NP_987100.1|refseq:NP_987101.1|refseq:XP_005263439.1|refseq:XP_005263440.1|refseq:XP_011530743.1|refseq:XP_016864365.1|refseq:XP_016864366.1|refseq:XP_016864367.1|refseq:XP_016864368.1|dip:DIP-50299N|ensembl:ENSG00000138757.15(gene)|ensembl:ENST00000359707.9(transcript)|ensembl:ENST00000395719.7(transcript)|ensembl:ENST00000676584.1(transcript)|ensembl:ENST00000676974.1(transcript)|ensembl:ENST00000677162.1(transcript)|ensembl:ENST00000677171.1(transcript)|ensembl:ENST00000677201.1(transcript)|ensembl:ENST00000677333.1(transcript)|ensembl:ENST00000677566.1(transcript)|ensembl:ENST00000677606.1(transcript)|ensembl:ENST00000677620.1(transcript)|ensembl:ENST00000678062.1(transcript)|ensembl:ENST00000678100.1(transcript)|ensembl:ENST00000678123.1(transcript)|ensembl:ENST00000678265.1(transcript)|ensembl:ENST00000678578.1(transcript)|ensembl:ENST00000678798.1(transcript)|ensembl:ENST00000678971.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007253""(obsolete cytoplasmic sequestering of NF-kappaB)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0034063""(stress granule assembly)|go:""GO:0045087""(innate immune response)|go:""GO:0051028""(mRNA transport)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0140693""(molecular condensate scaffold activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR035979|interpro:IPR039539|mint:Q9UN86|rcsb pdb:5DRV|reactome:R-HSA-9705671|panther:PTHR10693(orthology-group)"	"interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004522(Asparaginyl-tRNA synthetase, class IIb)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0004816""(asparagine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006421""(asparaginyl-tRNA aminoacylation)|go:""GO:0016740""(transferase activity)|refseq:WP_000432163.1|refseq:NP_847005.1|refseq:YP_030701.1|interpro:IPR045864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:bYP8U2wviIqJBWcnLQnuoV0MhV89606	rogid:mt3LZ6UiTSkQu3DvSutGoRSLUGM1392	intact-crc:21917FF2DB011CFA|rigid:61aaiLXijldhkqHlpSPv+WnHQX8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15117	uniprotkb:A0A6L7HFM3	intact:EBI-1753267|uniprotkb:O00359|uniprotkb:A8K2Y8|uniprotkb:E9PBV9|uniprotkb:Q9NZI9|uniprotkb:B4DLN2|ensembl:ENSP00000316460.7|ensembl:ENSP00000426346.1	intact:EBI-2811019|uniprotkb:Q6HU79|uniprotkb:Q6KNG3|uniprotkb:E9R8X8|uniprotkb:E9R8X9|uniprotkb:Q81MT6|uniprotkb:A0A0F7RCX3	psi-mi:fyb1_human(display_long)|uniprotkb:FYB1(gene name)|psi-mi:FYB1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLAP130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym)	psi-mi:a0a6l7hfm3_bacan(display_long)|uniprotkb:pyc(gene name)|psi-mi:pyc(display_short)|uniprotkb:GBAA_4157(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833545|imex:IM-13779-3770	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-42204N|efo:""Orphanet:566192""|ensembl:ENSG00000082074.19(gene)|ensembl:ENST00000351578.12(transcript)|ensembl:ENST00000515010.5(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008289""(lipid binding)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0032991""(protein-containing complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0070161""(anchoring junction)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|mint:O15117|rcsb pdb:1RI9|rcsb pdb:2GTJ|rcsb pdb:2GTO|reactome:R-HSA-202433|reactome:R-HSA-391160|refseq:NP_001230022.1|refseq:NP_001456.3|refseq:NP_955367.1|refseq:XP_006714527.1|refseq:XP_006714528.1|refseq:XP_006714529.1|refseq:XP_011512310.1|refseq:XP_011512311.1|refseq:XP_011512312.1|panther:PTHR16830(orthology-group)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011053(Single hybrid motif)|go:""GO:0004736""(pyruvate carboxylase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0046872""(metal ion binding)|interpro:IPR055268|refseq:WP_000164068.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ObeGCVefTolMBQGVT/WhglH5F009606	rogid:vk3wfrqt2MsmQkUObx8VTjcjDNs1392	intact-crc:25D512C093C6A126|rigid:NYXpF+E47up2MRSR8Rdlo1X3/nw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UN86	uniprotkb:A0A6H3AEH9	intact:EBI-1044298|uniprotkb:O60606|uniprotkb:O75149|uniprotkb:Q9UPA1|uniprotkb:A8K6X1|ensembl:ENSP00000352738.4|ensembl:ENSP00000379069.3|ensembl:ENSP00000503228.1|ensembl:ENSP00000503239.1|ensembl:ENSP00000503355.1|ensembl:ENSP00000503504.1|ensembl:ENSP00000503669.1|ensembl:ENSP00000503911.1|ensembl:ENSP00000503943.1|ensembl:ENSP00000504101.1|ensembl:ENSP00000504159.1|ensembl:ENSP00000504316.1|ensembl:ENSP00000504361.1|ensembl:ENSP00000504371.1|ensembl:ENSP00000504496.1|ensembl:ENSP00000504523.1|ensembl:ENSP00000504585.1|ensembl:ENSP00000504698.1|intact:EBI-21356833	intact:EBI-2825969|uniprotkb:Q6KQA7|uniprotkb:Q6HW51|uniprotkb:E9QXA7|uniprotkb:E9QXA8|uniprotkb:Q81MY8|uniprotkb:A0A1S0QZ62	psi-mi:g3bp2_human(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3BP2(gene name)|psi-mi:G3BP2(display_short)|uniprotkb:KIAA0660(gene name synonym)	psi-mi:a0a6h3aeh9_bacan(display_long)|uniprotkb:GBAA_3431(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833520|imex:IM-13779-3773	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036429.2|refseq:NP_987100.1|refseq:NP_987101.1|refseq:XP_005263439.1|refseq:XP_005263440.1|refseq:XP_011530743.1|refseq:XP_016864365.1|refseq:XP_016864366.1|refseq:XP_016864367.1|refseq:XP_016864368.1|dip:DIP-50299N|ensembl:ENSG00000138757.15(gene)|ensembl:ENST00000359707.9(transcript)|ensembl:ENST00000395719.7(transcript)|ensembl:ENST00000676584.1(transcript)|ensembl:ENST00000676974.1(transcript)|ensembl:ENST00000677162.1(transcript)|ensembl:ENST00000677171.1(transcript)|ensembl:ENST00000677201.1(transcript)|ensembl:ENST00000677333.1(transcript)|ensembl:ENST00000677566.1(transcript)|ensembl:ENST00000677606.1(transcript)|ensembl:ENST00000677620.1(transcript)|ensembl:ENST00000678062.1(transcript)|ensembl:ENST00000678100.1(transcript)|ensembl:ENST00000678123.1(transcript)|ensembl:ENST00000678265.1(transcript)|ensembl:ENST00000678578.1(transcript)|ensembl:ENST00000678798.1(transcript)|ensembl:ENST00000678971.1(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007253""(obsolete cytoplasmic sequestering of NF-kappaB)|go:""GO:0007265""(Ras protein signal transduction)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0030159""(signaling receptor complex adaptor activity)|go:""GO:0034063""(stress granule assembly)|go:""GO:0045087""(innate immune response)|go:""GO:0051028""(mRNA transport)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0062029""(positive regulation of stress granule assembly)|go:""GO:0140693""(molecular condensate scaffold activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR035979|interpro:IPR039539|mint:Q9UN86|rcsb pdb:5DRV|reactome:R-HSA-9705671|panther:PTHR10693(orthology-group)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR004849(6-phosphogluconate dehydrogenase related protein)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|go:""GO:0004616""(""phosphogluconate dehydrogenase (decarboxylating) activity"")|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0016054""(organic acid catabolic process)|go:""GO:0019521""(D-gluconate metabolic process)|go:""GO:0050661""(NADP binding)|refseq:WP_001195906.1|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:bYP8U2wviIqJBWcnLQnuoV0MhV89606	rogid:9xewZtuST2DIssVvl7EmWL6KWz81392	intact-crc:ED446DFE1104D223|rigid:EBw9op1nKfB28z+8PSdi8b+n5xQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15117	uniprotkb:A0A6L8PTK5	intact:EBI-1753267|uniprotkb:O00359|uniprotkb:A8K2Y8|uniprotkb:E9PBV9|uniprotkb:Q9NZI9|uniprotkb:B4DLN2|ensembl:ENSP00000316460.7|ensembl:ENSP00000426346.1	intact:EBI-2815740|uniprotkb:Q6KLC6|uniprotkb:Q6HS22|uniprotkb:E9R820|uniprotkb:E9R821|uniprotkb:Q81KM0|uniprotkb:A0A0F7R5G6	psi-mi:fyb1_human(display_long)|uniprotkb:FYB1(gene name)|psi-mi:FYB1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLAP130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym)	psi-mi:a0a6l8ptk5_bacan(display_long)|uniprotkb:GBAA_4976(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833552|imex:IM-13779-3771	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-42204N|efo:""Orphanet:566192""|ensembl:ENSG00000082074.19(gene)|ensembl:ENST00000351578.12(transcript)|ensembl:ENST00000515010.5(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008289""(lipid binding)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0032991""(protein-containing complex)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0070161""(anchoring junction)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|mint:O15117|rcsb pdb:1RI9|rcsb pdb:2GTJ|rcsb pdb:2GTO|reactome:R-HSA-202433|reactome:R-HSA-391160|refseq:NP_001230022.1|refseq:NP_001456.3|refseq:NP_955367.1|refseq:XP_006714527.1|refseq:XP_006714528.1|refseq:XP_006714529.1|refseq:XP_011512310.1|refseq:XP_011512311.1|refseq:XP_011512312.1|panther:PTHR16830(orthology-group)"	"interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0008146""(sulfotransferase activity)|go:""GO:0008641""(ubiquitin-like modifier activating enzyme activity)|go:""GO:0016779""(nucleotidyltransferase activity)|refseq:WP_001158094.1|interpro:IPR035985|interpro:IPR045886"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ObeGCVefTolMBQGVT/WhglH5F009606	rogid:uDGO+gtg3zkc7kwxZa3vzDK2sII1392	intact-crc:1DBF91FF8FD0C40C|rigid:5nUjZ8vrF1lsFJE3vTIc3Hn2k/w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BWH2	uniprotkb:A0A6L7HEN3	intact:EBI-714482|uniprotkb:Q9H2I6|uniprotkb:Q8NHX8|uniprotkb:B2R7W5|uniprotkb:D3DWY5|ensembl:ENSP00000358510.3	intact:EBI-2813673|uniprotkb:Q6HT23|uniprotkb:Q6KMB2|uniprotkb:E9RAX2|uniprotkb:E9RAX3|uniprotkb:Q81LL7|uniprotkb:A0A0F7RD65	psi-mi:fund2_human(display_long)|uniprotkb:HCC3(orf name)|uniprotkb:PD03104(orf name)|uniprotkb:FUNDC2(gene name)|psi-mi:FUNDC2(display_short)|uniprotkb:HCBP6(gene name synonym)|uniprotkb:Hepatitis C virus core-binding protein 6(gene name synonym)|uniprotkb:Cervical cancer proto-oncogene 3 protein(gene name synonym)|uniprotkb:DC44(orf name)	psi-mi:a0a6l7hen3_bacan(display_long)|uniprotkb:GBAA_4599(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833573|imex:IM-13779-3775	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_076423.2|ensembl:ENSG00000165775.18(gene)|ensembl:ENST00000369498.8(transcript)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0010543""(regulation of platelet activation)|go:""GO:0035356""(intracellular triglyceride homeostasis)|interpro:IPR007014(FUN14)|mint:Q9BWH2|panther:PTHR21346(orthology-group)"	"interpro:IPR001670(Iron-containing alcohol dehydrogenase)|interpro:IPR018211|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR012079(Bifunctional aldehyde/alcohol dehydrogenase)|go:""GO:0004022""(""alcohol dehydrogenase (NAD+) activity"")|go:""GO:0006066""(alcohol metabolic process)|go:""GO:0008774""(""acetaldehyde dehydrogenase (acetylating) activity"")|go:""GO:0015976""(carbon utilization)|go:""GO:0046872""(metal ion binding)|interpro:IPR039697|refseq:WP_000260483.1|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR034789"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oAN8aj9JpmBS5+YUfdh8Keehk3E9606	rogid:LtF87oi/0AhapD6hnHazpca+dWo1392	intact-crc:0BD247E5DAFE84A0|rigid:dX7z38b9H8k41GrpsXvelbuIe2s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PBA4	uniprotkb:Q9BWH2	intact:EBI-2811481|uniprotkb:Q6HWM6|uniprotkb:Q6KQR8|uniprotkb:E9R9K3|uniprotkb:E9R9K4|uniprotkb:Q81NG1|uniprotkb:A0A0F7RFB0	intact:EBI-714482|uniprotkb:Q9H2I6|uniprotkb:Q8NHX8|uniprotkb:B2R7W5|uniprotkb:D3DWY5|ensembl:ENSP00000358510.3	psi-mi:a0a6l8pba4_bacan(display_long)|uniprotkb:GBAA_3236(locus name)	psi-mi:fund2_human(display_long)|uniprotkb:HCC3(orf name)|uniprotkb:PD03104(orf name)|uniprotkb:FUNDC2(gene name)|psi-mi:FUNDC2(display_short)|uniprotkb:HCBP6(gene name synonym)|uniprotkb:Hepatitis C virus core-binding protein 6(gene name synonym)|uniprotkb:Cervical cancer proto-oncogene 3 protein(gene name synonym)|uniprotkb:DC44(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833566|imex:IM-13779-3777	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR027278|interpro:IPR005966(Pyridoxal phosphate-dependent deaminase)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|go:""GO:0019148""(D-cysteine desulfhydrase activity)|refseq:WP_001046577.1|interpro:IPR036052"	"refseq:NP_076423.2|ensembl:ENSG00000165775.18(gene)|ensembl:ENST00000369498.8(transcript)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0010543""(regulation of platelet activation)|go:""GO:0035356""(intracellular triglyceride homeostasis)|interpro:IPR007014(FUN14)|mint:Q9BWH2|panther:PTHR21346(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wppwoIBS9yJ6YJCkewhEheENTIg1392	rogid:oAN8aj9JpmBS5+YUfdh8Keehk3E9606	intact-crc:B4109F8D90E33D7D|rigid:0sqfqAWbuir0jK9LKrrpdCZv2Mc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35637	uniprotkb:A0A6L8NXF0	intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108.8	intact:EBI-2822995|uniprotkb:Q6I194|uniprotkb:Q6KV44|uniprotkb:E9RDE2|uniprotkb:E9RDE3|uniprotkb:Q81T13|uniprotkb:A0A1Q4M3L5	psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym)	psi-mi:a0a6l8nxf0_bacan(display_long)|uniprotkb:GBAA_1479(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833559|imex:IM-13779-3774	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR23238(orthology-group)|efo:""Orphanet:275872""|efo:""Orphanet:300605""|efo:""Orphanet:79105""|efo:""Orphanet:803""|efo:""Orphanet:99967""|ensembl:ENSG00000089280.20(gene)|ensembl:ENST00000254108.12(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008380""(RNA splicing)|go:""GO:0042802""(identical protein binding)|go:""GO:0043232""(intracellular membraneless organelle)|go:""GO:0043484""(regulation of RNA splicing)|go:""GO:0046872""(metal ion binding)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0051260""(protein homooligomerization)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0099523""(presynaptic cytosol)|go:""GO:0099524""(postsynaptic cytosol)|go:""GO:0140693""(molecular condensate scaffold activity)|go:""GO:0140694""(membraneless organelle assembly)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:1990000""(amyloid fibril formation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|rcsb pdb:7VQQ|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001164105.1|refseq:NP_004951.1|dip:DIP-29857N"	interpro:IPR002763(Protein of unknown function DUF72)|refseq:WP_000897346.1|interpro:IPR036520	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606	rogid:u1sZiTg4rdlUG2mmKDCV0by4crM1392	intact-crc:CAE554B139AD241E|rigid:s6B2CHaXP8KWUSYbJFV7Oea1Y3s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81Z75	uniprotkb:P07954	intact:EBI-2809631|uniprotkb:Q6KXS8|uniprotkb:E9QUA4	intact:EBI-1050358|uniprotkb:B1ANK7|ensembl:ENSP00000355518.4	psi-mi:q81z75_bacan(display_long)|uniprotkb:GBAA_0397(locus name)	psi-mi:fumh_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833593|imex:IM-13779-3778	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000161178.1|go:""GO:0016020""(membrane)"	"dip:DIP-46920N|ensembl:ENSG00000091483.8(gene)|ensembl:ENST00000366560.4(transcript)|go:""GO:0000050""(urea cycle)|go:""GO:0000821""(regulation of arginine metabolic process)|go:""GO:0004333""(fumarate hydratase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006106""(fumarate metabolic process)|go:""GO:0006108""(malate metabolic process)|go:""GO:0006281""(DNA repair)|go:""GO:0006525""(arginine metabolic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042393""(histone binding)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|mint:P07954|rcsb pdb:3E04|rcsb pdb:5D6B|rcsb pdb:5UPP|rcsb pdb:6EBT|rcsb pdb:6V8F|rcsb pdb:6VBE|rcsb pdb:7LUB|reactome:R-HSA-71403|reactome:R-HSA-9837999|refseq:NP_000134.2|efo:""Orphanet:24""|efo:""Orphanet:29072""|efo:""Orphanet:523""|panther:PTHR11444(orthology-group)|ensembl:ENSP00000355518.4"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/24	rogid:5bjDxf1Ab9R5iOfEMs3IVYjFxcE1392	rogid:Jukx6wt0vi49nxgaTzdz5x1Q2Mc9606	intact-crc:59B6DC3A48512DB7|rigid:9+/82ofi5icyrSxUD8tZzQ6dWzU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81S64	uniprotkb:P07954	intact:EBI-2833583|uniprotkb:Q6I0E7|uniprotkb:Q6KUB4	intact:EBI-1050358|uniprotkb:B1ANK7|ensembl:ENSP00000355518.4	psi-mi:asna_bacan(display_long)|uniprotkb:asnA(gene name)|psi-mi:asnA(display_short)|uniprotkb:Asparagine synthetase A(gene name synonym)|uniprotkb:BA_1808(locus name)|uniprotkb:GBAA_1808(locus name)|uniprotkb:BAS1673(locus name)	psi-mi:fumh_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833580|imex:IM-13779-3776	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004071""(aspartate-ammonia ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0016740""(transferase activity)|go:""GO:0070981""(L-asparagine biosynthetic process)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004618(Aspartate--ammonia ligase)|refseq:WP_000284908.1|refseq:NP_844231.1|refseq:YP_027939.1|interpro:IPR045864"	"dip:DIP-46920N|ensembl:ENSG00000091483.8(gene)|ensembl:ENST00000366560.4(transcript)|go:""GO:0000050""(urea cycle)|go:""GO:0000821""(regulation of arginine metabolic process)|go:""GO:0004333""(fumarate hydratase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006106""(fumarate metabolic process)|go:""GO:0006108""(malate metabolic process)|go:""GO:0006281""(DNA repair)|go:""GO:0006525""(arginine metabolic process)|go:""GO:0006974""(DNA damage response)|go:""GO:0035861""(site of double-strand break)|go:""GO:0042393""(histone binding)|go:""GO:0048873""(homeostasis of number of cells within a tissue)|go:""GO:0070062""(extracellular exosome)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:2001034""(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|mint:P07954|rcsb pdb:3E04|rcsb pdb:5D6B|rcsb pdb:5UPP|rcsb pdb:6EBT|rcsb pdb:6V8F|rcsb pdb:6VBE|rcsb pdb:7LUB|reactome:R-HSA-71403|reactome:R-HSA-9837999|refseq:NP_000134.2|efo:""Orphanet:24""|efo:""Orphanet:29072""|efo:""Orphanet:523""|panther:PTHR11444(orthology-group)|ensembl:ENSP00000355518.4"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/24	rogid:utMPSVZmKsgxl2mG4VRijQuOrIw1392	rogid:Jukx6wt0vi49nxgaTzdz5x1Q2Mc9606	intact-crc:53F1253A480D8C8A|rigid:j3rPgetMg1fNn8Nan+BOq63xI1U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P2Q2	uniprotkb:Q81W03	intact:EBI-1104786|uniprotkb:A7E2Y3|uniprotkb:Q5T377|ensembl:ENSP00000350032.2	intact:EBI-2816847|uniprotkb:Q6I506|uniprotkb:Q6KYQ0	psi-mi:frm4a_human(display_long)|uniprotkb:FRMD4A(gene name)|psi-mi:FRMD4A(display_short)|uniprotkb:FRMD4(gene name synonym)|uniprotkb:KIAA1294(gene name synonym)	psi-mi:sym1_bacan(display_long)|uniprotkb:metG1(gene name)|psi-mi:metG1(display_short)|uniprotkb:metG(gene name synonym)|uniprotkb:metS(gene name synonym)|uniprotkb:BA_0036(locus name)|uniprotkb:GBAA_0036(locus name)|uniprotkb:BAS0037(locus name)|uniprotkb:Methionyl-tRNA synthetase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833612|imex:IM-13779-3780	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000151474.23(gene)|ensembl:ENST00000357447.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0050709""(negative regulation of protein secretion)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0090162""(establishment of epithelial cell polarity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR021774|interpro:IPR029071|interpro:IPR035963|interpro:IPR041785|interpro:IPR047176|refseq:NP_001305265.1|refseq:NP_001305266.1|refseq:NP_001305267.1|refseq:NP_060497.3|efo:""Orphanet:466688""|panther:PTHR46079(orthology-group)"	"interpro:IPR015413(""Aminoacyl-tRNA synthetase, class I (M)"")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004495(Methionyl-tRNA synthetase, class Ia, beta subunit, C-terminal)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023457|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|go:""GO:0000049""(tRNA binding)|go:""GO:0004825""(methionine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006431""(methionyl-tRNA aminoacylation)|interpro:IPR033911|interpro:IPR041872|refseq:NP_842605.1|refseq:YP_026324.1|refseq:WP_000134128.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TGegbzrzYRVh8STG9OoMSIL3WOQ9606	rogid:UV6NoFqVLKRIPMXdNWd52Fysfxg1392	intact-crc:42538CC06B24C0C8|rigid:pxO9aJumnsUI+AMZIo9TVV5uVbE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8Q3J2	uniprotkb:Q9P2Q2	intact:EBI-2824405|uniprotkb:Q6HWZ5|uniprotkb:Q6KR27|uniprotkb:E9QQT3|uniprotkb:E9QQT4|uniprotkb:Q81NS5|uniprotkb:A0A0F7RAF0	intact:EBI-1104786|uniprotkb:A7E2Y3|uniprotkb:Q5T377|ensembl:ENSP00000350032.2	psi-mi:a0a6l8q3j2_bacan(display_long)|uniprotkb:cutC(gene name)|psi-mi:cutC(display_short)|uniprotkb:GBAA_3100(locus name)	psi-mi:frm4a_human(display_long)|uniprotkb:FRMD4A(gene name)|psi-mi:FRMD4A(display_short)|uniprotkb:FRMD4(gene name synonym)|uniprotkb:KIAA1294(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833633|imex:IM-13779-3779	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005627(CutC)|rcsb pdb:4R9X|go:""GO:0005507""(copper ion binding)|go:""GO:0005737""(cytoplasm)|interpro:IPR036822|refseq:WP_000895086.1"	"ensembl:ENSG00000151474.23(gene)|ensembl:ENST00000357447.7(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005912""(adherens junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0050709""(negative regulation of protein secretion)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0090162""(establishment of epithelial cell polarity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR021774|interpro:IPR029071|interpro:IPR035963|interpro:IPR041785|interpro:IPR047176|refseq:NP_001305265.1|refseq:NP_001305266.1|refseq:NP_001305267.1|refseq:NP_060497.3|efo:""Orphanet:466688""|panther:PTHR46079(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/Hl6H8iEFWnVcF6xGjLoDRBmPQQ1392	rogid:TGegbzrzYRVh8STG9OoMSIL3WOQ9606	intact-crc:3615C7003167318C|rigid:aa5BrgDRbuws2Ywj9HWGaRFou1Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P42345	uniprotkb:A0A6L8PL93	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|intact:EBI-28989074|ensembl:ENSP00000354558.4|ensembl:ENSP00000515200.2	intact:EBI-2812142|uniprotkb:Q6HXW8|uniprotkb:Q6KRZ0|uniprotkb:E9R374|uniprotkb:E9R375|uniprotkb:Q81PQ4|uniprotkb:A0A0F7RGT7	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)|uniprotkb:Tyrosine-protein kinase mTOR(gene name synonym)	psi-mi:a0a6l8pl93_bacan(display_long)|uniprotkb:ypeB(gene name)|psi-mi:ypeB(display_short)|uniprotkb:GBAA_2747(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833619|imex:IM-13779-3781	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:269001""|efo:""Orphanet:269008""|efo:""Orphanet:457485""|efo:""Orphanet:99802""|ensembl:ENSG00000198793.14(gene)|ensembl:ENST00000361445.9(transcript)|ensembl:ENST00000703143.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000822""(inositol hexakisphosphate binding)|go:""GO:0001002""(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:""GO:0001003""(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:""GO:0001006""(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:""GO:0001156""(TFIIIC-class transcription factor complex binding)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002296""(T-helper 1 cell lineage commitment)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003179""(heart valve morphogenesis)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006112""(energy reserve metabolic process)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007281""(germ cell development)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009408""(response to heat)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010831""(positive regulation of myotube differentiation)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0016605""(PML body)|go:""GO:0019228""(neuronal action potential)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030425""(dendrite)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031529""(ruffle organization)|go:""GO:0031641""(regulation of myelination)|go:""GO:0031648""(protein destabilization)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0031670""(cellular response to nutrient)|go:""GO:0031929""(TOR signaling)|go:""GO:0031931""(TORC1 complex)|go:""GO:0031932""(TORC2 complex)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0038203""(TORC2 signaling)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043200""(response to amino acid)|go:""GO:0043276""(anoikis)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045670""(regulation of osteoclast differentiation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0045945""(positive regulation of transcription by RNA polymerase III)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046889""(positive regulation of lipid biosynthetic process)|go:""GO:0048266""(behavioral response to pain)|go:""GO:0048511""(rhythmic process)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050882""(voluntary musculoskeletal movement)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055013""(cardiac muscle cell development)|go:""GO:0060048""(cardiac muscle contraction)|go:""GO:0061431""(cellular response to methionine)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071470""(cellular response to osmotic stress)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090559""(regulation of membrane permeability)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1903691""(positive regulation of wound healing, spreading of epidermal cells)|go:""GO:1904059""(regulation of locomotor rhythm)|go:""GO:1904690""(positive regulation of cytoplasmic translational initiation)|go:""GO:1905671""(regulation of lysosome organization)|go:""GO:1905672""(negative regulation of lysosome organization)|go:""GO:1905857""(positive regulation of pentose-phosphate shunt)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990253""(cellular response to leucine starvation)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|interpro:IPR050517|mint:P42345|rcsb pdb:1AUE|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|rcsb pdb:7EPD|rcsb pdb:7OWG|rcsb pdb:7PE7|rcsb pdb:7PE8|rcsb pdb:7PE9|rcsb pdb:7PEA|rcsb pdb:7PEB|rcsb pdb:7PEC|rcsb pdb:7TZO|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8ER6|rcsb pdb:8ER7|rcsb pdb:8ERA|rcsb pdb:8PPZ|rcsb pdb:8RCH|rcsb pdb:8RCK|rcsb pdb:8RCN|rcsb pdb:9F44|rcsb pdb:9F45|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|reactome:R-HSA-9856530|refseq:NP_004949.1|refseq:XP_005263495.1|dip:DIP-790N|panther:PTHR11139(orthology-group)|ensembl:ENSP00000354558.4|ensembl:ENSP00000515200.2"	"interpro:IPR014239(Spore germination YpeB)|go:""GO:0009847""(spore germination)|refseq:WP_000943708.1|interpro:IPR025711|interpro:IPR048402"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	rogid:ArcU2AZZMp9ttGHYayHY+K9lpzU1392	intact-crc:BA11A4D8947C8B6A|rigid:9uZOnBEmh8HnVP0LQasNtQ4/hAE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96AE4	uniprotkb:A0A6L7HMR2	intact:EBI-711404|ensembl:ENSP00000359804.2|uniprotkb:Q12828	intact:EBI-2833600|uniprotkb:Q6KW31|uniprotkb:Q6I298|uniprotkb:E9QWY4|uniprotkb:E9QWY5|uniprotkb:A0A2P0HB37|uniprotkb:Q81U13	psi-mi:fubp1_human(display_long)|uniprotkb:FUBP1(gene name)|psi-mi:FUBP1(display_short)|uniprotkb:DNA helicase V(gene name synonym)	psi-mi:a0a6l7hmr2_bacan(display_long)|uniprotkb:GBAA_1081(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833605|imex:IM-13779-3782	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000162613.18(gene)|ensembl:ENST00000370768.7(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010628""(positive regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|interpro:IPR048249|interpro:IPR048250|interpro:IPR048251|interpro:IPR048252|mint:Q96AE4|rcsb pdb:1J4W|rcsb pdb:2KXH|rcsb pdb:4LIJ|rcsb pdb:6Y24|rcsb pdb:6Y2C|rcsb pdb:6Y2D|rcsb pdb:8P25|refseq:NP_003893.2|refseq:NP_001290362.1|refseq:XP_016858232.1|dip:DIP-47273N|panther:PTHR10288(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR017501(Phage infection protein, YhgE,  C-terminal)|interpro:IPR017500(Phage infection protein, YhgE,  N-terminal)|interpro:IPR023908|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|refseq:WP_000678106.1|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR051328"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:38IaQgYv8qLMAryXO0lbfzgjjsM9606	rogid:p2G9pkUsJ8PQ90xujqBHn20l93o1392	intact-crc:7DEEE63ABB234C01|rigid:EANBvEgP/0rWSymwhGmPktNjUqo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PE10	uniprotkb:P14324	intact:EBI-2818555|uniprotkb:Q6KTZ8|uniprotkb:Q6I019|uniprotkb:E9R2B8|uniprotkb:E9R2B9|uniprotkb:Q81RU2|uniprotkb:A0A0F7RJ75	intact:EBI-948245|uniprotkb:Q96G29|uniprotkb:D3DV91|uniprotkb:E9PCI9|ensembl:ENSP00000349078.6|ensembl:ENSP00000357340.4	psi-mi:a0a6l8pe10_bacan(display_long)|uniprotkb:GBAA_1945(locus name)	"psi-mi:fpps_human(display_long)|uniprotkb:Farnesyl diphosphate synthase(gene name synonym)|uniprotkb:FDPS(gene name)|psi-mi:FDPS(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:KIAA1293(gene name synonym)|uniprotkb:""(2E,6E)-farnesyl diphosphate synthase""(gene name synonym)|uniprotkb:Dimethylallyltranstransferase(gene name synonym)|uniprotkb:Geranyltranstransferase(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833626|imex:IM-13779-3783	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR014216(""ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD"")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR039421|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034040""(ATPase-coupled lipid transmembrane transporter activity)|go:""GO:0042883""(cysteine transport)|go:""GO:0140359""(ABC-type transporter activity)|refseq:WP_000824065.1|interpro:IPR036640"	"ensembl:ENSG00000160752.15(gene)|ensembl:ENST00000356657.10(transcript)|ensembl:ENST00000368356.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004161""(dimethylallyltranstransferase activity)|go:""GO:0004337""(""(2E,6E)-farnesyl diphosphate synthase activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005777""(peroxisome)|go:""GO:0005829""(cytosol)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0033384""(geranyl diphosphate biosynthetic process)|go:""GO:0045337""(farnesyl diphosphate biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|interpro:IPR039702|mint:P14324|rcsb pdb:1YQ7|rcsb pdb:1YV5|rcsb pdb:1ZW5|rcsb pdb:2F7M|rcsb pdb:2F89|rcsb pdb:2F8C|rcsb pdb:2F8Z|rcsb pdb:2F92|rcsb pdb:2F94|rcsb pdb:2F9K|rcsb pdb:2OPM|rcsb pdb:2OPN|rcsb pdb:2QIS|rcsb pdb:2RAH|rcsb pdb:2VF6|rcsb pdb:3B7L|rcsb pdb:3CP6|rcsb pdb:3N1V|rcsb pdb:3N1W|rcsb pdb:3N3L|rcsb pdb:3N45|rcsb pdb:3N46|rcsb pdb:3N49|rcsb pdb:3N5H|rcsb pdb:3N5J|rcsb pdb:3N6K|rcsb pdb:3RYE|rcsb pdb:3S4J|rcsb pdb:4DEM|rcsb pdb:4GA3|rcsb pdb:4H5C|rcsb pdb:4H5D|rcsb pdb:4H5E|rcsb pdb:4JVJ|rcsb pdb:4KFA|rcsb pdb:4KPD|rcsb pdb:4KPJ|rcsb pdb:4KQ5|rcsb pdb:4KQS|rcsb pdb:4KQU|rcsb pdb:4L2X|rcsb pdb:4LFV|rcsb pdb:4LPG|rcsb pdb:4LPH|rcsb pdb:4N1Z|rcsb pdb:4N9U|rcsb pdb:4NFI|rcsb pdb:4NFJ|rcsb pdb:4NFK|rcsb pdb:4NG6|rcsb pdb:4NKE|rcsb pdb:4NKF|rcsb pdb:4NUA|rcsb pdb:4OGU|rcsb pdb:4P0V|rcsb pdb:4P0W|rcsb pdb:4P0X|rcsb pdb:4PVX|rcsb pdb:4PVY|rcsb pdb:4Q23|rcsb pdb:4QPF|rcsb pdb:4QXS|rcsb pdb:4RXA|rcsb pdb:4XQR|rcsb pdb:4XQS|rcsb pdb:4XQT|rcsb pdb:5CG5|rcsb pdb:5CG6|rcsb pdb:5DGM|rcsb pdb:5DGN|rcsb pdb:5DGS|rcsb pdb:5DIQ|rcsb pdb:5DJP|rcsb pdb:5DJR|rcsb pdb:5DJV|rcsb pdb:5JA0|rcsb pdb:5JUZ|rcsb pdb:5JV0|rcsb pdb:5JV1|rcsb pdb:5JV2|rcsb pdb:5KSX|rcsb pdb:5YGI|rcsb pdb:6N7Y|rcsb pdb:6N7Z|rcsb pdb:6N82|rcsb pdb:6N83|rcsb pdb:6OAG|rcsb pdb:6OAH|reactome:R-HSA-191273|reactome:R-HSA-2426168|refseq:NP_001129293.1|refseq:NP_001129294.1|refseq:NP_001229753.1|refseq:NP_001229754.1|refseq:NP_001995.1|refseq:XP_005245019.1|refseq:XP_005245020.1|dip:DIP-50059N|efo:""Orphanet:79152""|panther:PTHR11525(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7XCFAONaGDISWIyfy6ZvZMJ+Gh81392	rogid:cLrS58XE4dKJiiK96hQt7JPO5T89606	intact-crc:968699076AB6E72A|rigid:PiHnb5lv8W4Btyf7ynUrwgR8d0Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0J1KLZ7	uniprotkb:Q92802	intact:EBI-2822063|uniprotkb:Q6KJ42|uniprotkb:E9R5M8|uniprotkb:Q81N06	intact:EBI-2514973|uniprotkb:A3KME8|ensembl:ENSP00000267068.3|ensembl:ENSP00000501416.1|ensembl:ENSP00000501516.1|ensembl:ENSP00000501518.1|ensembl:ENSP00000501537.1	psi-mi:a0a0j1klz7_bacan(display_long)|uniprotkb:GBAA_3413(locus name)	psi-mi:n42l2_human(display_long)|uniprotkb:N4BP2L2(gene name)|psi-mi:N4BP2L2(display_short)|uniprotkb:CG005(gene name synonym)|uniprotkb:PFAAP5(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833668|imex:IM-13779-3786	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_000945244.1	"refseq:XP_016875836.1|refseq:XP_016875837.1|refseq:XP_016875838.1|refseq:NP_055702.1|ensembl:ENSG00000244754.9(gene)|ensembl:ENST00000267068.6(transcript)|ensembl:ENST00000674349.1(transcript)|ensembl:ENST00000674421.1(transcript)|ensembl:ENST00000674465.1(transcript)|ensembl:ENST00000674484.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001824""(blastocyst development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019899""(enzyme binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902035""(positive regulation of hematopoietic stem cell proliferation)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|interpro:IPR026302|interpro:IPR027417|mint:Q92802|panther:PTHR13308(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t8CroOX3cma9aG7JpLpi9U1ql8U1392	rogid:a7wRNCzoB/ImcDT7U8E5355qX1A9606	intact-crc:FCBB353ABED0E31E|rigid:J1LXF1oWY26NfV8oWe+jp0AgCAw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81U22	uniprotkb:P42345	intact:EBI-2814904|uniprotkb:Q6KW38|uniprotkb:Q6I2A7	intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|intact:EBI-28989074|ensembl:ENSP00000354558.4|ensembl:ENSP00000515200.2	psi-mi:cpfc1_bacan(display_long)|uniprotkb:cpfC1(gene name)|psi-mi:cpfC1(display_short)|uniprotkb:hemH-1(gene name synonym)|uniprotkb:hemH1(gene name synonym)|uniprotkb:BAS1000(locus name)|uniprotkb:BA_1071(locus name)|uniprotkb:GBAA_1071(locus name)	psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym)|uniprotkb:Tyrosine-protein kinase mTOR(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833640|imex:IM-13779-3788	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|rcsb pdb:2C8J|interpro:IPR033644|interpro:IPR033659|go:""GO:0004325""(ferrochelatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:NP_843565.1|refseq:YP_027273.1|refseq:WP_000726793.1"	"efo:""Orphanet:269001""|efo:""Orphanet:269008""|efo:""Orphanet:457485""|efo:""Orphanet:99802""|ensembl:ENSG00000198793.14(gene)|ensembl:ENST00000361445.9(transcript)|ensembl:ENST00000703143.2(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000822""(inositol hexakisphosphate binding)|go:""GO:0001002""(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:""GO:0001003""(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:""GO:0001006""(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:""GO:0001156""(TFIIIC-class transcription factor complex binding)|go:""GO:0001558""(regulation of cell growth)|go:""GO:0002296""(T-helper 1 cell lineage commitment)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003179""(heart valve morphogenesis)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006112""(energy reserve metabolic process)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0006974""(DNA damage response)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0007281""(germ cell development)|go:""GO:0008361""(regulation of cell size)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009408""(response to heat)|go:""GO:0009791""(post-embryonic development)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010592""(positive regulation of lamellipodium assembly)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010831""(positive regulation of myotube differentiation)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0016605""(PML body)|go:""GO:0019228""(neuronal action potential)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030425""(dendrite)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031529""(ruffle organization)|go:""GO:0031641""(regulation of myelination)|go:""GO:0031648""(protein destabilization)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0031670""(cellular response to nutrient)|go:""GO:0031929""(TOR signaling)|go:""GO:0031931""(TORC1 complex)|go:""GO:0031932""(TORC2 complex)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0033173""(calcineurin-NFAT signaling cascade)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0038202""(TORC1 signaling)|go:""GO:0038203""(TORC2 signaling)|go:""GO:0042752""(regulation of circadian rhythm)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043200""(response to amino acid)|go:""GO:0043276""(anoikis)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0045670""(regulation of osteoclast differentiation)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0045821""(positive regulation of glycolytic process)|go:""GO:0045945""(positive regulation of transcription by RNA polymerase III)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0046889""(positive regulation of lipid biosynthetic process)|go:""GO:0048266""(behavioral response to pain)|go:""GO:0048511""(rhythmic process)|go:""GO:0048709""(oligodendrocyte differentiation)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050882""(voluntary musculoskeletal movement)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0051496""(positive regulation of stress fiber assembly)|go:""GO:0051549""(positive regulation of keratinocyte migration)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055013""(cardiac muscle cell development)|go:""GO:0060048""(cardiac muscle contraction)|go:""GO:0061431""(cellular response to methionine)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071470""(cellular response to osmotic stress)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090559""(regulation of membrane permeability)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1901838""(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:""GO:1903691""(positive regulation of wound healing, spreading of epidermal cells)|go:""GO:1904059""(regulation of locomotor rhythm)|go:""GO:1904690""(positive regulation of cytoplasmic translational initiation)|go:""GO:1905671""(regulation of lysosome organization)|go:""GO:1905672""(negative regulation of lysosome organization)|go:""GO:1905857""(positive regulation of pentose-phosphate shunt)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990253""(cellular response to leucine starvation)|go:""GO:2000785""(regulation of autophagosome assembly)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|interpro:IPR050517|mint:P42345|rcsb pdb:1AUE|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|rcsb pdb:7EPD|rcsb pdb:7OWG|rcsb pdb:7PE7|rcsb pdb:7PE8|rcsb pdb:7PE9|rcsb pdb:7PEA|rcsb pdb:7PEB|rcsb pdb:7PEC|rcsb pdb:7TZO|rcsb pdb:7UXC|rcsb pdb:7UXH|rcsb pdb:8ER6|rcsb pdb:8ER7|rcsb pdb:8ERA|rcsb pdb:8PPZ|rcsb pdb:8RCH|rcsb pdb:8RCK|rcsb pdb:8RCN|rcsb pdb:9F44|rcsb pdb:9F45|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|reactome:R-HSA-9856530|refseq:NP_004949.1|refseq:XP_005263495.1|dip:DIP-790N|panther:PTHR11139(orthology-group)|ensembl:ENSP00000354558.4|ensembl:ENSP00000515200.2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/23	rogid:VgwkMIvazgaeCD8Rq+iY6Sn7gk01392	rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606	intact-crc:02F466943F368ADB|rigid:IAVXSLRXk/0ObPBNQewEntIL/HU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14324	uniprotkb:A0A2B3Y6C6	intact:EBI-948245|uniprotkb:Q96G29|uniprotkb:D3DV91|uniprotkb:E9PCI9|ensembl:ENSP00000349078.6|ensembl:ENSP00000357340.4	intact:EBI-2809836|uniprotkb:A0A1V4BKN1|uniprotkb:Q6HS64|uniprotkb:Q6KLG4|uniprotkb:E9R1Z0|uniprotkb:E9R1Z1|uniprotkb:Q81KQ8	"psi-mi:fpps_human(display_long)|uniprotkb:Farnesyl diphosphate synthase(gene name synonym)|uniprotkb:FDPS(gene name)|psi-mi:FDPS(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:KIAA1293(gene name synonym)|uniprotkb:""(2E,6E)-farnesyl diphosphate synthase""(gene name synonym)|uniprotkb:Dimethylallyltranstransferase(gene name synonym)|uniprotkb:Geranyltranstransferase(gene name synonym)"	psi-mi:a0a2b3y6c6_bacan(display_long)|uniprotkb:GBAA_4932(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833647|imex:IM-13779-3784	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000160752.15(gene)|ensembl:ENST00000356657.10(transcript)|ensembl:ENST00000368356.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004161""(dimethylallyltranstransferase activity)|go:""GO:0004337""(""(2E,6E)-farnesyl diphosphate synthase activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005777""(peroxisome)|go:""GO:0005829""(cytosol)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0033384""(geranyl diphosphate biosynthetic process)|go:""GO:0045337""(farnesyl diphosphate biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|interpro:IPR039702|mint:P14324|rcsb pdb:1YQ7|rcsb pdb:1YV5|rcsb pdb:1ZW5|rcsb pdb:2F7M|rcsb pdb:2F89|rcsb pdb:2F8C|rcsb pdb:2F8Z|rcsb pdb:2F92|rcsb pdb:2F94|rcsb pdb:2F9K|rcsb pdb:2OPM|rcsb pdb:2OPN|rcsb pdb:2QIS|rcsb pdb:2RAH|rcsb pdb:2VF6|rcsb pdb:3B7L|rcsb pdb:3CP6|rcsb pdb:3N1V|rcsb pdb:3N1W|rcsb pdb:3N3L|rcsb pdb:3N45|rcsb pdb:3N46|rcsb pdb:3N49|rcsb pdb:3N5H|rcsb pdb:3N5J|rcsb pdb:3N6K|rcsb pdb:3RYE|rcsb pdb:3S4J|rcsb pdb:4DEM|rcsb pdb:4GA3|rcsb pdb:4H5C|rcsb pdb:4H5D|rcsb pdb:4H5E|rcsb pdb:4JVJ|rcsb pdb:4KFA|rcsb pdb:4KPD|rcsb pdb:4KPJ|rcsb pdb:4KQ5|rcsb pdb:4KQS|rcsb pdb:4KQU|rcsb pdb:4L2X|rcsb pdb:4LFV|rcsb pdb:4LPG|rcsb pdb:4LPH|rcsb pdb:4N1Z|rcsb pdb:4N9U|rcsb pdb:4NFI|rcsb pdb:4NFJ|rcsb pdb:4NFK|rcsb pdb:4NG6|rcsb pdb:4NKE|rcsb pdb:4NKF|rcsb pdb:4NUA|rcsb pdb:4OGU|rcsb pdb:4P0V|rcsb pdb:4P0W|rcsb pdb:4P0X|rcsb pdb:4PVX|rcsb pdb:4PVY|rcsb pdb:4Q23|rcsb pdb:4QPF|rcsb pdb:4QXS|rcsb pdb:4RXA|rcsb pdb:4XQR|rcsb pdb:4XQS|rcsb pdb:4XQT|rcsb pdb:5CG5|rcsb pdb:5CG6|rcsb pdb:5DGM|rcsb pdb:5DGN|rcsb pdb:5DGS|rcsb pdb:5DIQ|rcsb pdb:5DJP|rcsb pdb:5DJR|rcsb pdb:5DJV|rcsb pdb:5JA0|rcsb pdb:5JUZ|rcsb pdb:5JV0|rcsb pdb:5JV1|rcsb pdb:5JV2|rcsb pdb:5KSX|rcsb pdb:5YGI|rcsb pdb:6N7Y|rcsb pdb:6N7Z|rcsb pdb:6N82|rcsb pdb:6N83|rcsb pdb:6OAG|rcsb pdb:6OAH|reactome:R-HSA-191273|reactome:R-HSA-2426168|refseq:NP_001129293.1|refseq:NP_001129294.1|refseq:NP_001229753.1|refseq:NP_001229754.1|refseq:NP_001995.1|refseq:XP_005245019.1|refseq:XP_005245020.1|dip:DIP-50059N|efo:""Orphanet:79152""|panther:PTHR11525(orthology-group)"	"interpro:IPR009293(Protein of unknown function DUF948, bacterial)|go:""GO:0016020""(membrane)|refseq:WP_001197726.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cLrS58XE4dKJiiK96hQt7JPO5T89606	rogid:bq85IyqkiV02z9B9bgDu4A+z+cU1392	intact-crc:83A5AAFFF862C698|rigid:DPEWD12lQzCdjixVxEqa5IxRSD8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92802	uniprotkb:Q9RN24	intact:EBI-2514973|uniprotkb:A3KME8|ensembl:ENSP00000267068.3|ensembl:ENSP00000501416.1|ensembl:ENSP00000501516.1|ensembl:ENSP00000501518.1|ensembl:ENSP00000501537.1	intact:EBI-2816910|uniprotkb:A0A6L7HE57	psi-mi:n42l2_human(display_long)|uniprotkb:N4BP2L2(gene name)|psi-mi:N4BP2L2(display_short)|uniprotkb:CG005(gene name synonym)|uniprotkb:PFAAP5(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 5(gene name synonym)	psi-mi:q9rn24_bacan(display_long)|uniprotkb:GBAA_pXO2_0007(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833654|imex:IM-13779-3787	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_016875836.1|refseq:XP_016875837.1|refseq:XP_016875838.1|refseq:NP_055702.1|ensembl:ENSG00000244754.9(gene)|ensembl:ENST00000267068.6(transcript)|ensembl:ENST00000674349.1(transcript)|ensembl:ENST00000674421.1(transcript)|ensembl:ENST00000674465.1(transcript)|ensembl:ENST00000674484.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001824""(blastocyst development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019899""(enzyme binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902035""(positive regulation of hematopoietic stem cell proliferation)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|interpro:IPR026302|interpro:IPR027417|mint:Q92802|panther:PTHR13308(orthology-group)"	"interpro:IPR047194|interpro:IPR023346|interpro:IPR000064(NLP/P60)|refseq:NP_053163.1|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0016020""(membrane)|interpro:IPR051202|refseq:WP_000741673.1|interpro:IPR038765"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:a7wRNCzoB/ImcDT7U8E5355qX1A9606	rogid:oo9JGo2PaH2O7caZYeDaCfURuFc1392	intact-crc:8CF4CB0001AD1518|rigid:kVcrikxno0Cgk3+KpUfvTfTbNHU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92802	uniprotkb:A0A6L8PJX4	intact:EBI-2514973|uniprotkb:A3KME8|ensembl:ENSP00000267068.3|ensembl:ENSP00000501416.1|ensembl:ENSP00000501516.1|ensembl:ENSP00000501518.1|ensembl:ENSP00000501537.1	intact:EBI-2824122|uniprotkb:Q6I4D5|uniprotkb:Q6KY38|uniprotkb:E9R8L8|uniprotkb:E9R8L9|uniprotkb:Q81VD3|uniprotkb:A0A0F7RK18	psi-mi:n42l2_human(display_long)|uniprotkb:N4BP2L2(gene name)|psi-mi:N4BP2L2(display_short)|uniprotkb:CG005(gene name synonym)|uniprotkb:PFAAP5(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 5(gene name synonym)	psi-mi:a0a6l8pjx4_bacan(display_long)|uniprotkb:GBAA_0276(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833661|imex:IM-13779-3785	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_016875836.1|refseq:XP_016875837.1|refseq:XP_016875838.1|refseq:NP_055702.1|ensembl:ENSG00000244754.9(gene)|ensembl:ENST00000267068.6(transcript)|ensembl:ENST00000674349.1(transcript)|ensembl:ENST00000674421.1(transcript)|ensembl:ENST00000674465.1(transcript)|ensembl:ENST00000674484.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001824""(blastocyst development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0017053""(transcription repressor complex)|go:""GO:0019899""(enzyme binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902035""(positive regulation of hematopoietic stem cell proliferation)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|interpro:IPR026302|interpro:IPR027417|mint:Q92802|panther:PTHR13308(orthology-group)"	"interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|go:""GO:0008146""(sulfotransferase activity)|go:""GO:0016020""(membrane)|refseq:WP_000790065.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:a7wRNCzoB/ImcDT7U8E5355qX1A9606	rogid:nhNgj94Gy3K33pZyXmxjj7lGkqs1392	intact-crc:5BFF79B4D67BC4B7|rigid:4mybzHZkxuXMsbUFtjiUwxVU1Ug	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P85037	uniprotkb:Q81LQ9	intact:EBI-2509974|ensembl:ENSP00000328720.4	intact:EBI-2817908|uniprotkb:Q6KMF4|uniprotkb:E9RE75	psi-mi:foxk1_human(display_long)|uniprotkb:FOXK1(gene name)|psi-mi:FOXK1(display_short)|uniprotkb:MNF(gene name synonym)|uniprotkb:Myocyte nuclear factor(gene name synonym)	psi-mi:q81lq9_bacan(display_long)|uniprotkb:comEA(gene name)|psi-mi:comEA(display_short)|uniprotkb:GBAA_4553(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833696|imex:IM-13779-3791	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011513493.1|refseq:NP_001032242.1|ensembl:ENSG00000164916.11(gene)|ensembl:ENST00000328914.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001678""(intracellular glucose homeostasis)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007517""(muscle organ development)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0030154""(cell differentiation)|go:""GO:0042594""(response to starvation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR047394|mint:P85037|rcsb pdb:8BZM|reactome:R-HSA-5689603|panther:PTHR45881(orthology-group)"	"interpro:IPR004509(Competence protein ComEA, helix-hairpin-helix region)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR019554|go:""GO:0003677""(DNA binding)|go:""GO:0006281""(DNA repair)|go:""GO:0015627""(type II protein secretion system complex)|go:""GO:0015628""(protein secretion by the type II secretion system)|go:""GO:0016020""(membrane)|interpro:IPR051675"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ngoE3oNlIDGkTf1ZMYG4OQ6lvE09606	rogid:iEvG41gaFu5NjfUyZipFRqUjSKs1392	intact-crc:D24C7A38E0267774|rigid:6mx/Tu+593HIH0Kk6ZsFWPWwPKI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H334	uniprotkb:A0A6L7HA16	intact:EBI-983809|uniprotkb:Q9H332|uniprotkb:Q9H333|uniprotkb:Q9P0R1|intact:EBI-28984754|uniprotkb:A3QVP8|uniprotkb:Q9BSG9|uniprotkb:B3KV70|uniprotkb:G5E9V8|ensembl:ENSP00000318902.5|ensembl:ENSP00000418102.1|ensembl:ENSP00000496990.1|ensembl:ENSP00000497344.1|ensembl:ENSP00000497369.1|ensembl:ENSP00000497454.2|uniprotkb:Q8NAN6	intact:EBI-2814138|uniprotkb:Q6HQ53|uniprotkb:Q6F078|uniprotkb:E9RDY5|uniprotkb:E9RDY6|uniprotkb:Q81JL0|uniprotkb:A0A0F7R8Z5	psi-mi:foxp1_human(display_long)|uniprotkb:FOXP1(gene name)|psi-mi:FOXP1(display_short)|uniprotkb:Mac-1-regulated forkhead(gene name synonym)|uniprotkb:HSPC215(orf name)	psi-mi:a0a6l7ha16_bacan(display_long)|uniprotkb:GBAA_5694(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833675|imex:IM-13779-3789	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:391372""|efo:""Orphanet:52417""|efo:""Orphanet:585877""|ensembl:ENSG00000114861.24(gene)|ensembl:ENST00000318789.11(transcript)|ensembl:ENST00000498215.7(transcript)|ensembl:ENST00000648380.1(transcript)|ensembl:ENST00000649528.3(transcript)|ensembl:ENST00000649631.1(transcript)|ensembl:ENST00000650068.2(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0002903""(negative regulation of B cell apoptotic process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006974""(DNA damage response)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0021756""(striatum development)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032651""(regulation of interleukin-1 beta production)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032745""(positive regulation of interleukin-21 production)|go:""GO:0033574""(response to testosterone)|go:""GO:0036035""(osteoclast development)|go:""GO:0042116""(macrophage activation)|go:""GO:0042117""(monocyte activation)|go:""GO:0042118""(endothelial cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045655""(regulation of monocyte differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050861""(positive regulation of B cell receptor signaling pathway)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0061052""(negative regulation of cell growth involved in cardiac muscle cell development)|go:""GO:0061470""(T follicular helper cell differentiation)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:1900424""(regulation of defense response to bacterium)|go:""GO:1901256""(regulation of macrophage colony-stimulating factor production)|go:""GO:1901300""(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:""GO:1901509""(regulation of endothelial tube morphogenesis)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000341""(""regulation of chemokine (C-X-C motif) ligand 2 production"")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|interpro:IPR047412|interpro:IPR050998|mint:Q9H334|rcsb pdb:2KIU|reactome:R-HSA-452723|refseq:NP_001012523.1|refseq:NP_001231737.1|refseq:NP_001231739.1|refseq:NP_001231741.1|refseq:NP_001231743.1|refseq:NP_001231744.1|refseq:NP_001231745.1|refseq:NP_116071.2|refseq:XP_006713165.1|refseq:XP_006713166.1|refseq:XP_006713167.1|refseq:XP_011531886.1|refseq:XP_011531887.1|refseq:XP_016861654.1|refseq:XP_016861655.1|refseq:XP_016861657.1|dip:DIP-36585N|panther:PTHR45796(orthology-group)|ensembl:ENST00000318779.7|ensembl:ENSP00000318721.3|ensembl:ENSP00000318902.5|ensembl:ENST00000484350.5|ensembl:ENSP00000417857.1|ensembl:ENST00000493089.7|ensembl:ENSP00000418524.1|ensembl:ENSP00000418102.1|ensembl:ENSP00000497344.1|ensembl:ENST00000648426.1|ensembl:ENSP00000498110.1|ensembl:ENST00000648710.2|ensembl:ENSP00000497430.2|ensembl:ENST00000648718.1|ensembl:ENSP00000496810.1|ensembl:ENSP00000497369.1|ensembl:ENSP00000496990.1|ensembl:ENSP00000497454.2"	"interpro:IPR000060(BCCT transporter)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_001242469.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/19	rogid:NREo12e1TLPfsul6Ie0l62NqIa89606	rogid:/tOiU2i3Pj5531YNTX3x8RYSwk01392	intact-crc:48AD6E108B5F3138|rigid:4bMf18k6lmTk4HEtd6kW/pzgwaU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H334	uniprotkb:Q81MN9	intact:EBI-983809|uniprotkb:Q9H332|uniprotkb:Q9H333|uniprotkb:Q9P0R1|intact:EBI-28984754|uniprotkb:A3QVP8|uniprotkb:Q9BSG9|uniprotkb:B3KV70|uniprotkb:G5E9V8|ensembl:ENSP00000318902.5|ensembl:ENSP00000418102.1|ensembl:ENSP00000496990.1|ensembl:ENSP00000497344.1|ensembl:ENSP00000497369.1|ensembl:ENSP00000497454.2|uniprotkb:Q8NAN6	intact:EBI-2810639|uniprotkb:Q6HU35|uniprotkb:Q6KNB9	psi-mi:foxp1_human(display_long)|uniprotkb:FOXP1(gene name)|psi-mi:FOXP1(display_short)|uniprotkb:Mac-1-regulated forkhead(gene name synonym)|uniprotkb:HSPC215(orf name)	psi-mi:ppk1_bacan(display_long)|uniprotkb:ppk(gene name)|psi-mi:ppk(display_short)|uniprotkb:ATP-polyphosphate phosphotransferase(gene name synonym)|uniprotkb:Polyphosphoric acid kinase(gene name synonym)|uniprotkb:BA_4208(locus name)|uniprotkb:GBAA_4208(locus name)|uniprotkb:BAS3903(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833682|imex:IM-13779-3792	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:391372""|efo:""Orphanet:52417""|efo:""Orphanet:585877""|ensembl:ENSG00000114861.24(gene)|ensembl:ENST00000318789.11(transcript)|ensembl:ENST00000498215.7(transcript)|ensembl:ENST00000648380.1(transcript)|ensembl:ENST00000649528.3(transcript)|ensembl:ENST00000649631.1(transcript)|ensembl:ENST00000650068.2(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001046""(core promoter sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0002903""(negative regulation of B cell apoptotic process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006974""(DNA damage response)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0021756""(striatum development)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032651""(regulation of interleukin-1 beta production)|go:""GO:0032655""(regulation of interleukin-12 production)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032745""(positive regulation of interleukin-21 production)|go:""GO:0033574""(response to testosterone)|go:""GO:0036035""(osteoclast development)|go:""GO:0042116""(macrophage activation)|go:""GO:0042117""(monocyte activation)|go:""GO:0042118""(endothelial cell activation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045655""(regulation of monocyte differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050727""(regulation of inflammatory response)|go:""GO:0050861""(positive regulation of B cell receptor signaling pathway)|go:""GO:0060766""(negative regulation of androgen receptor signaling pathway)|go:""GO:0061052""(negative regulation of cell growth involved in cardiac muscle cell development)|go:""GO:0061470""(T follicular helper cell differentiation)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:1900424""(regulation of defense response to bacterium)|go:""GO:1901256""(regulation of macrophage colony-stimulating factor production)|go:""GO:1901300""(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:""GO:1901509""(regulation of endothelial tube morphogenesis)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:2000341""(""regulation of chemokine (C-X-C motif) ligand 2 production"")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|interpro:IPR047412|interpro:IPR050998|mint:Q9H334|rcsb pdb:2KIU|reactome:R-HSA-452723|refseq:NP_001012523.1|refseq:NP_001231737.1|refseq:NP_001231739.1|refseq:NP_001231741.1|refseq:NP_001231743.1|refseq:NP_001231744.1|refseq:NP_001231745.1|refseq:NP_116071.2|refseq:XP_006713165.1|refseq:XP_006713166.1|refseq:XP_006713167.1|refseq:XP_011531886.1|refseq:XP_011531887.1|refseq:XP_016861654.1|refseq:XP_016861655.1|refseq:XP_016861657.1|dip:DIP-36585N|panther:PTHR45796(orthology-group)|ensembl:ENST00000318779.7|ensembl:ENSP00000318721.3|ensembl:ENSP00000318902.5|ensembl:ENST00000484350.5|ensembl:ENSP00000417857.1|ensembl:ENST00000493089.7|ensembl:ENSP00000418524.1|ensembl:ENSP00000418102.1|ensembl:ENSP00000497344.1|ensembl:ENST00000648426.1|ensembl:ENSP00000498110.1|ensembl:ENST00000648710.2|ensembl:ENSP00000497430.2|ensembl:ENST00000648718.1|ensembl:ENSP00000496810.1|ensembl:ENSP00000497369.1|ensembl:ENSP00000496990.1|ensembl:ENSP00000497454.2"	"interpro:IPR003414(Polyphosphate kinase)|interpro:IPR025198|interpro:IPR025200|interpro:IPR024953|go:""GO:0005524""(ATP binding)|go:""GO:0006799""(polyphosphate biosynthetic process)|go:""GO:0008976""(polyphosphate kinase activity)|go:""GO:0009358""(polyphosphate kinase complex)|go:""GO:0046872""(metal ion binding)|refseq:WP_000423561.1|interpro:IPR036830|interpro:IPR036832|interpro:IPR041108|refseq:NP_846443.1|refseq:YP_030153.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/19	rogid:NREo12e1TLPfsul6Ie0l62NqIa89606	rogid:XAQtpZmDcBUTqfHyM89FQx4seQo1392	intact-crc:298AAE98F6378A41|rigid:JseTcN5UM1Tkbnd9A9nE5VEG4ww	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81Y46	uniprotkb:Q01167	intact:EBI-2812495|uniprotkb:Q6KPL0|uniprotkb:Q6HVE1	intact:EBI-2509991|intact:EBI-28976610|uniprotkb:Q13624|uniprotkb:Q13623|uniprotkb:A6NEP5|uniprotkb:Q13622|ensembl:ENSP00000335677.5	psi-mi:hutu_bacan(display_long)|uniprotkb:hutU(gene name)|psi-mi:hutU(display_short)|uniprotkb:Imidazolonepropionate hydrolase(gene name synonym)|uniprotkb:BA_3711(locus name)|uniprotkb:GBAA_3711(locus name)|uniprotkb:BAS3441(locus name)	psi-mi:foxk2_human(display_long)|uniprotkb:G/T-mismatch specific binding protein(gene name synonym)|uniprotkb:FOXK2(gene name)|psi-mi:FOXK2(display_short)|uniprotkb:ILF(gene name synonym)|uniprotkb:ILF1(gene name synonym)|uniprotkb:Interleukin enhancer-binding factor 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833689|imex:IM-13779-3790	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR035085|interpro:IPR023636|interpro:IPR023637|go:""GO:0005737""(cytoplasm)|go:""GO:0016153""(urocanate hydratase activity)|go:""GO:0019556""(L-histidine catabolic process to glutamate and formamide)|go:""GO:0019557""(L-histidine catabolic process to glutamate and formate)|refseq:WP_000416715.1|interpro:IPR038364|interpro:IPR035401|interpro:IPR035400|interpro:IPR036190|refseq:NP_845974.1|refseq:YP_029697.1"	"refseq:NP_004505.2|ensembl:ENSG00000141568.21(gene)|ensembl:ENST00000335255.10(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001678""(intracellular glucose homeostasis)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010906""(regulation of glucose metabolic process)|go:""GO:0042594""(response to starvation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061621""(canonical glycolysis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR047397|interpro:IPR047398|mint:Q01167|rcsb pdb:1JXS|rcsb pdb:2C6Y|reactome:R-HSA-5689603|panther:PTHR45881(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bokqO9GavtjceeT8eQKHFW32guU1392	rogid:mGYtlnM3enVAuU82j5hQ0sui3F49606	intact-crc:D4FE60D9B7A0473E|rigid:UuCc+50PZ0rPs7VabidIGleCZGw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75044	uniprotkb:A0A2P0HLN8	intact:EBI-1051034|uniprotkb:A2RUF3|ensembl:ENSP00000459615.2	intact:EBI-2810906	psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym)	psi-mi:a0a2p0hln8_bacan(display_long)|uniprotkb:spo0J(gene name)|psi-mi:spo0J(display_short)|uniprotkb:BA_5729(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833703|imex:IM-13779-3793	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001164108.1|refseq:NP_056141.2|dip:DIP-37618N|refseq:XP_005277567.1|ensembl:ENSG00000266028.8(gene)|ensembl:ENST00000573034.8(transcript)|go:""GO:0003363""(lamellipodium assembly involved in ameboidal cell migration)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0014069""(postsynaptic density)|go:""GO:0021816""(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:""GO:0030027""(lamellipodium)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031267""(small GTPase binding)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043547""(positive regulation of GTPase activity)|go:""GO:0044327""(dendritic spine head)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0046847""(filopodium assembly)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0051014""(actin filament severing)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0060996""(dendritic spine development)|go:""GO:1904861""(excitatory synapse assembly)|go:""GO:1904862""(inhibitory synapse assembly)|go:""GO:2001223""(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|interpro:IPR051627|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|panther:PTHR14166(orthology-group)"	"interpro:IPR050336|interpro:IPR003115(ParB-like nuclease)|interpro:IPR004437(ParB-like partition protein)|interpro:IPR036086|go:""GO:0003677""(DNA binding)|go:""GO:0005694""(chromosome)|go:""GO:0007059""(chromosome segregation)|go:""GO:0045881""(positive regulation of sporulation resulting in formation of a cellular spore)|uniprotkb:A0A2K1VHE8(uniprot-removed-ac)|interpro:IPR041468|refseq:NP_847874.2|refseq:WP_001051841.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/28	rogid:/0NBTrPy/51L4LGytNP/80OifEE9606	rogid:yZl0oXOncYOEs5/ejxEfcSQuNoE1392	intact-crc:E88667804B7DDF92|rigid:1TDlp4+KGlrmZywMu9xyKGMcVME	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PRJ9	uniprotkb:P21333	intact:EBI-2815525|uniprotkb:Q6KW87|uniprotkb:Q6I2G0|uniprotkb:E9R5M4|uniprotkb:E9R5M5|uniprotkb:Q81U73|uniprotkb:A0A0F7RMK7	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45|ensembl:ENSP00000358866.3	psi-mi:a0a6l8prj9_bacan(display_long)|uniprotkb:GBAA_1011(locus name)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833735|imex:IM-13779-3797	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR027417|go:""GO:0016020""(membrane)|refseq:WP_003158389.1"	"efo:""Orphanet:1826""|efo:""Orphanet:2301""|efo:""Orphanet:2484""|efo:""Orphanet:482606""|efo:""Orphanet:555877""|efo:""Orphanet:75497""|efo:""Orphanet:88630""|efo:""Orphanet:90650""|efo:""Orphanet:90652""|efo:""Orphanet:98892""|efo:""Orphanet:99811""|ensembl:ENSG00000196924.19(gene)|ensembl:ENST00000369850.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002102""(podosome)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007195""(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:""GO:0007597""(blood coagulation, intrinsic pathway)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016479""(negative regulation of transcription by RNA polymerase I)|go:""GO:0019900""(kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031523""(Myb complex)|go:""GO:0032233""(positive regulation of actin filament bundle assembly)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043204""(perikaryon)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0044295""(axonal growth cone)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0046332""(SMAD binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050808""(synapse organization)|go:""GO:0050821""(protein stabilization)|go:""GO:0051015""(actin filament binding)|go:""GO:0051020""(GTPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090042""(tubulin deacetylation)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0097368""(establishment of Sertoli cell barrier)|go:""GO:0097440""(apical dendrite)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901381""(positive regulation of potassium ion transmembrane transport)|go:""GO:1902396""(protein localization to bicellular tight junction)|go:""GO:1905000""(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:""GO:1905031""(regulation of membrane repolarization during cardiac muscle cell action potential)|go:""GO:1990779""(glycoprotein Ib-IX-V complex)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|go:""GO:2001224""(positive regulation of neuron migration)|rcsb pdb:6EW1|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|rcsb pdb:7SC4|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|rcsb pdb:7SFT|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|refseq:NP_001104026.1|refseq:NP_001447.2|dip:DIP-1136N|panther:PTHR38537(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:ekIUPDK8T+zMQc5QBJxM4T9lOqY1392	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	intact-crc:42FA0B791BEEA2A5|rigid:v5LnFfawHSU6Tulu2fXeXD/4s1w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q06828	uniprotkb:A0A6L8NWA5	intact:EBI-2833710|ensembl:ENSP00000347041.4|uniprotkb:Q8IV47|uniprotkb:Q15331	intact:EBI-2833716|uniprotkb:Q6KTH9|uniprotkb:Q6HZI9|uniprotkb:E9QSW2|uniprotkb:E9QSW3|uniprotkb:Q81RB6|uniprotkb:A0A0F7RCS7	psi-mi:fmod_human(display_long)|uniprotkb:FMOD(gene name)|psi-mi:FMOD(display_short)|uniprotkb:FM(gene name synonym)|uniprotkb:SLRR2E(gene name synonym)|uniprotkb:Collagen-binding 59 kDa protein(gene name synonym)|uniprotkb:Keratan sulfate proteoglycan fibromodulin(gene name synonym)	psi-mi:a0a6l8nwa5_bacan(display_long)|uniprotkb:GBAA_2134(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833721|imex:IM-13779-3798	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000122176.12(gene)|ensembl:ENST00000354955.5(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005796""(Golgi lumen)|go:""GO:0007181""(transforming growth factor beta receptor complex assembly)|go:""GO:0030199""(collagen fibril organization)|go:""GO:0031012""(extracellular matrix)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR050333|mint:Q06828|rcsb pdb:5MX0|reactome:R-HSA-2022854|reactome:R-HSA-2022857|reactome:R-HSA-3000178|reactome:R-HSA-3656225|reactome:R-HSA-3656243|reactome:R-HSA-3656244|refseq:NP_002014.2|panther:PTHR45712(orthology-group)"	"go:""GO:0004792""(thiosulfate-cyanide sulfurtransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0008146""(sulfotransferase activity)|go:""GO:0008641""(ubiquitin-like modifier activating enzyme activity)|go:""GO:0016779""(nucleotidyltransferase activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|refseq:WP_001158136.1|interpro:IPR035985|interpro:IPR045886"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UeFgeq6sE7Q5zA0WmfhL+q3pgh49606	rogid:icfwmu8KBBvByw88DfK/kGrjylQ1392	intact-crc:BFF206B99BFAFD97|rigid:TF2+fFglEWflyrr22vXPZdbeL6E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A348A8F7	uniprotkb:P21333	intact:EBI-2833745|uniprotkb:Q6HUJ0|uniprotkb:Q6KNS6|uniprotkb:E9R049|uniprotkb:E9R050|uniprotkb:Q81WE3|uniprotkb:A0A1J9WIV5|uniprotkb:A0A3P1UAB3	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45|ensembl:ENSP00000358866.3	psi-mi:a0a348a8f7_bacan(display_long)|uniprotkb:divIVA(gene name)|psi-mi:divIVA(display_short)|uniprotkb:GBAA_4035(locus name)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833742|imex:IM-13779-3795	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005737""(cytoplasm)|go:""GO:0051301""(cell division)|interpro:IPR007793(DivIVA)|interpro:IPR019933|refseq:WP_001131611.1"	"efo:""Orphanet:1826""|efo:""Orphanet:2301""|efo:""Orphanet:2484""|efo:""Orphanet:482606""|efo:""Orphanet:555877""|efo:""Orphanet:75497""|efo:""Orphanet:88630""|efo:""Orphanet:90650""|efo:""Orphanet:90652""|efo:""Orphanet:98892""|efo:""Orphanet:99811""|ensembl:ENSG00000196924.19(gene)|ensembl:ENST00000369850.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002102""(podosome)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007195""(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:""GO:0007597""(blood coagulation, intrinsic pathway)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016479""(negative regulation of transcription by RNA polymerase I)|go:""GO:0019900""(kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031523""(Myb complex)|go:""GO:0032233""(positive regulation of actin filament bundle assembly)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043204""(perikaryon)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0044295""(axonal growth cone)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0046332""(SMAD binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050808""(synapse organization)|go:""GO:0050821""(protein stabilization)|go:""GO:0051015""(actin filament binding)|go:""GO:0051020""(GTPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090042""(tubulin deacetylation)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0097368""(establishment of Sertoli cell barrier)|go:""GO:0097440""(apical dendrite)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901381""(positive regulation of potassium ion transmembrane transport)|go:""GO:1902396""(protein localization to bicellular tight junction)|go:""GO:1905000""(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:""GO:1905031""(regulation of membrane repolarization during cardiac muscle cell action potential)|go:""GO:1990779""(glycoprotein Ib-IX-V complex)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|go:""GO:2001224""(positive regulation of neuron migration)|rcsb pdb:6EW1|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|rcsb pdb:7SC4|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|rcsb pdb:7SFT|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|refseq:NP_001104026.1|refseq:NP_001447.2|dip:DIP-1136N|panther:PTHR38537(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:EbqHkp/nfWO5orH7Lhq5ED5P+a41392	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	intact-crc:E8C1D64D2638400B|rigid:ehKqpSCEY5nvSTmaMlwtCfnmeqE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3Q0PRJ6	uniprotkb:P21333	intact:EBI-2810680|uniprotkb:Q6KR31|uniprotkb:Q6HWZ9|uniprotkb:E9R4P7|uniprotkb:E9R4P8|uniprotkb:Q81NS9|uniprotkb:A0A0F7RCF4	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45|ensembl:ENSP00000358866.3	psi-mi:a0a3q0prj6_bacan(display_long)|uniprotkb:GBAA_3096(locus name)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833728|imex:IM-13779-3794	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003778(Allophanate hydrolase subunit 2)|interpro:IPR052708|interpro:IPR029000|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)"	"efo:""Orphanet:1826""|efo:""Orphanet:2301""|efo:""Orphanet:2484""|efo:""Orphanet:482606""|efo:""Orphanet:555877""|efo:""Orphanet:75497""|efo:""Orphanet:88630""|efo:""Orphanet:90650""|efo:""Orphanet:90652""|efo:""Orphanet:98892""|efo:""Orphanet:99811""|ensembl:ENSG00000196924.19(gene)|ensembl:ENST00000369850.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001664""(G protein-coupled receptor binding)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0002102""(podosome)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003723""(RNA binding)|go:""GO:0005080""(protein kinase C binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007195""(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:""GO:0007597""(blood coagulation, intrinsic pathway)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0015459""(potassium channel regulator activity)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016479""(negative regulation of transcription by RNA polymerase I)|go:""GO:0019900""(kinase binding)|go:""GO:0021943""(formation of radial glial scaffolds)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030018""(Z disc)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031523""(Myb complex)|go:""GO:0032233""(positive regulation of actin filament bundle assembly)|go:""GO:0032432""(actin filament bundle)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034988""(Fc-gamma receptor I complex binding)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042789""(mRNA transcription by RNA polymerase II)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043113""(receptor clustering)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043198""(dendritic shaft)|go:""GO:0043204""(perikaryon)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0044295""(axonal growth cone)|go:""GO:0044319""(wound healing, spreading of cells)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045022""(early endosome to late endosome transport)|go:""GO:0045184""(establishment of protein localization)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0046332""(SMAD binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048680""(positive regulation of axon regeneration)|go:""GO:0050808""(synapse organization)|go:""GO:0050821""(protein stabilization)|go:""GO:0051015""(actin filament binding)|go:""GO:0051020""(GTPase binding)|go:""GO:0051209""(release of sequestered calcium ion into cytosol)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0060271""(cilium assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090042""(tubulin deacetylation)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:0097368""(establishment of Sertoli cell barrier)|go:""GO:0097440""(apical dendrite)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:1900026""(positive regulation of substrate adhesion-dependent cell spreading)|go:""GO:1901381""(positive regulation of potassium ion transmembrane transport)|go:""GO:1902396""(protein localization to bicellular tight junction)|go:""GO:1905000""(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:""GO:1905031""(regulation of membrane repolarization during cardiac muscle cell action potential)|go:""GO:1990779""(glycoprotein Ib-IX-V complex)|go:""GO:2000179""(positive regulation of neural precursor cell proliferation)|go:""GO:2001046""(positive regulation of integrin-mediated signaling pathway)|go:""GO:2001224""(positive regulation of neuron migration)|rcsb pdb:6EW1|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|rcsb pdb:7SC4|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|rcsb pdb:7SFT|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|refseq:NP_001104026.1|refseq:NP_001447.2|dip:DIP-1136N|panther:PTHR38537(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:NUa3lWGCm+fzNXodfOc6AoaBPi01392	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	intact-crc:8544EE97F95F90B8|rigid:rgstHyDeWvLJ1XFB0thMRIXw+EI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H9A7	uniprotkb:Q14318	intact:EBI-2816086|uniprotkb:Q6KKA3|uniprotkb:Q6HQY4|uniprotkb:E9QWA3|uniprotkb:E9QWA4|uniprotkb:Q81X48|uniprotkb:A0A1J9WVL8	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|uniprotkb:C8C9T5|ensembl:ENSP00000222308.4|ensembl:ENSP00000472302.1	psi-mi:a0a6l7h9a7_bacan(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:GBAA_5395(locus name)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833755|imex:IM-13779-3796	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009380""(excinuclease repair complex)|go:""GO:0009381""(excinuclease ABC activity)|go:""GO:0009432""(SOS response)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_000045565.1|interpro:IPR041102|interpro:IPR041552|interpro:IPR013815(ATP-grasp fold, subdomain 1)"	"refseq:NP_036313.3|refseq:XP_011526165.1|refseq:NP_001295302.1|ensembl:ENSG00000105701.16(gene)|ensembl:ENST00000222308.8(transcript)|ensembl:ENST00000596558.6(transcript)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005740""(mitochondrial envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006915""(apoptotic process)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0021904""(dorsal/ventral neural tube patterning)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0043010""(camera-type eye development)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0048665""(neuron fate specification)|go:""GO:0070585""(protein localization to mitochondrion)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|go:""GO:1901524""(regulation of mitophagy)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR046357|interpro:IPR050754|mint:Q14318|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|dip:DIP-42200N|panther:PTHR46512(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:8J+yjOUWiDCOsqLZUtYwrwWzv241392	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	intact-crc:15B0B65368BA5616|rigid:YNLgF1xmtF+2Y2hf3ujIuETIGYw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14318	uniprotkb:Q81PB7	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|uniprotkb:C8C9T5|ensembl:ENSP00000222308.4|ensembl:ENSP00000472302.1	intact:EBI-2833762|uniprotkb:Q6KRK7|uniprotkb:E9QU80	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:q81pb7_bacan(display_long)|uniprotkb:GBAA_2894(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833767|imex:IM-13779-3799	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_036313.3|refseq:XP_011526165.1|refseq:NP_001295302.1|ensembl:ENSG00000105701.16(gene)|ensembl:ENST00000222308.8(transcript)|ensembl:ENST00000596558.6(transcript)|go:""GO:0001933""(negative regulation of protein phosphorylation)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005740""(mitochondrial envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0006915""(apoptotic process)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0021904""(dorsal/ventral neural tube patterning)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0043010""(camera-type eye development)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046872""(metal ion binding)|go:""GO:0048665""(neuron fate specification)|go:""GO:0070585""(protein localization to mitochondrion)|go:""GO:0097718""(disordered domain specific binding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|go:""GO:1901524""(regulation of mitophagy)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR046357|interpro:IPR050754|mint:Q14318|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|dip:DIP-42200N|panther:PTHR46512(orthology-group)"	"go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	rogid:zyT25eyk+dxNWcv9cDI4nOBGwpg1392	intact-crc:EBA8903DB6720092|rigid:/SMQ6EfDveDw6nKbPbJevWMJ5fU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7RGR7	uniprotkb:Q5TD97	intact:EBI-2819394|uniprotkb:Q6I2U9|uniprotkb:Q6KWM6|uniprotkb:E9QUJ7|uniprotkb:E9QUJ8|uniprotkb:Q81UL9	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022.2|ensembl:ENSP00000396390.2|ensembl:ENSP00000442357.1	psi-mi:a0a0f7rgr7_bacan(display_long)|uniprotkb:GBAA_0845(locus name)	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833788|imex:IM-13779-3801	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000232525.1|interpro:IPR002293(Amino acid/polyamine transporter I)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR050367"	"refseq:NP_065228.4|refseq:NP_001164278.1|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214.11(gene)|ensembl:ENST00000326771.2(transcript)|ensembl:ENST00000450218.6(transcript)|ensembl:ENST00000541107.5(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0030018""(Z disc)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|panther:PTHR24205(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gd40RQX3lNK/T190F5PhGoo0iYU1392	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	intact-crc:C823A8CC512535FF|rigid:1sCABa8FILZoz7M3LPkY5QjvjcM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A1J9WCP3	uniprotkb:P26885	intact:EBI-2812130|uniprotkb:Q6KXZ3|uniprotkb:Q6I487|uniprotkb:E9R189|uniprotkb:E9R190|uniprotkb:Q81ZE1|uniprotkb:A0A0J1HRK2	intact:EBI-719873|uniprotkb:Q5BJH9|uniprotkb:Q9BTS7|ensembl:ENSP00000310935.4|ensembl:ENSP00000398147.2	psi-mi:a0a1j9wcp3_bacan(display_long)|uniprotkb:GBAA_0328(locus name)	psi-mi:fkbp2_human(display_long)|uniprotkb:FK506-binding protein 2(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP13(gene name synonym)|uniprotkb:FKBP2(gene name)|psi-mi:FKBP2(display_short)|uniprotkb:FKBP13(gene name synonym)|uniprotkb:13 kDa FK506-binding protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833781|imex:IM-13779-3800	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000390(Small multidrug resistance protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_000263260.1|interpro:IPR045324"	"refseq:NP_001128680.1|refseq:NP_004461.2|refseq:NP_476433.1|refseq:XP_005273905.1|ensembl:ENSG00000173486.14(gene)|ensembl:ENST00000309366.9(transcript)|ensembl:ENST00000449942.6(transcript)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005528""(FK506 binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR044609|interpro:IPR046357|mint:P26885|rcsb pdb:2PBC|rcsb pdb:4NNR|panther:PTHR45779(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kNnvGEtfbtmZ3WYcCWH4ScQCMOU1392	rogid:xxpKgBsHnQysq1kpGy/jfQ6qmLo9606	intact-crc:7CD127D47411D5BD|rigid:1tIp5YpsV4kv9gDoWavYaEzcQuI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14192	uniprotkb:Q81U22	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	intact:EBI-2814904|uniprotkb:Q6KW38|uniprotkb:Q6I2A7	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:cpfc1_bacan(display_long)|uniprotkb:cpfC1(gene name)|psi-mi:cpfC1(display_short)|uniprotkb:hemH-1(gene name synonym)|uniprotkb:hemH1(gene name synonym)|uniprotkb:BAS1000(locus name)|uniprotkb:BA_1071(locus name)|uniprotkb:GBAA_1071(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833795|imex:IM-13779-3803	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|rcsb pdb:2C8J|interpro:IPR033644|interpro:IPR033659|go:""GO:0004325""(ferrochelatase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006783""(heme biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:NP_843565.1|refseq:YP_027273.1|refseq:WP_000726793.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	rogid:VgwkMIvazgaeCD8Rq+iY6Sn7gk01392	intact-crc:5BC4F02098512436|rigid:ekh8PhHffL0CCbKtHch4MjYVasM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81K97	uniprotkb:Q02790	intact:EBI-2822925|uniprotkb:Q6KL14|uniprotkb:Q6HRP7	intact:EBI-1047444|uniprotkb:D3DUQ1|uniprotkb:Q9UCP1|uniprotkb:Q9UCV7|ensembl:ENSP00000001008.4	psi-mi:mene_bacan(display_long)|uniprotkb:menE(gene name)|psi-mi:menE(display_short)|uniprotkb:o-succinylbenzoyl-CoA synthetase(gene name synonym)|uniprotkb:BA_5108(locus name)|uniprotkb:GBAA_5108(locus name)|uniprotkb:BAS4747(locus name)	psi-mi:fkbp4_human(display_long)|uniprotkb:FK506-binding protein 4(gene name synonym)|uniprotkb:HSP-binding immunophilin(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:52 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBP59(gene name synonym)|uniprotkb:Immunophilin FKBP52(gene name synonym)|uniprotkb:FKBP4(gene name)|psi-mi:FKBP4(display_short)|uniprotkb:FKBP52(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:59 kDa immunophilin(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833774|imex:IM-13779-3802	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR010192(O-succinylbenzoate-CoA ligase)|interpro:IPR025110|refseq:WP_000449553.1|go:""GO:0005524""(ATP binding)|go:""GO:0008756""(o-succinylbenzoate-CoA ligase activity)|go:""GO:0009234""(menaquinone biosynthetic process)|interpro:IPR042099|interpro:IPR050237|refseq:NP_847294.1|refseq:YP_030991.1|interpro:IPR045851"	"refseq:NP_002005.1|ensembl:ENSG00000004478.8(gene)|ensembl:ENST00000001008.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003755""(peptidyl-prolyl cis-trans isomerase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005525""(GTP binding)|go:""GO:0005528""(FK506 binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0005874""(microtubule)|go:""GO:0006457""(protein folding)|go:""GO:0006463""(steroid hormone receptor complex assembly)|go:""GO:0006825""(copper ion transport)|go:""GO:0007566""(embryo implantation)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030850""(prostate gland development)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031111""(negative regulation of microtubule polymerization or depolymerization)|go:""GO:0031115""(negative regulation of microtubule polymerization)|go:""GO:0031503""(protein-containing complex localization)|go:""GO:0032767""(copper-dependent protein binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0035259""(nuclear glucocorticoid receptor binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044295""(axonal growth cone)|go:""GO:0046661""(male sex differentiation)|go:""GO:0048156""(tau protein binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0061077""(chaperone-mediated protein folding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR046357|interpro:IPR050754|mint:Q02790|rcsb pdb:1N1A|rcsb pdb:1P5Q|rcsb pdb:1Q1C|rcsb pdb:1QZ2|rcsb pdb:4DRJ|rcsb pdb:4LAV|rcsb pdb:4LAW|rcsb pdb:4LAX|rcsb pdb:4LAY|rcsb pdb:4TW8|rcsb pdb:6RCY|rcsb pdb:8FFV|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|dip:DIP-50866N|panther:PTHR10516(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:3/TxyNygK8jLtTSE5V04NYB2SLU1392	rogid:N0vDRDgcQ2x8xiWKdX9Zt+cHcsQ9606	intact-crc:9D47812E0F2E2442|rigid:+8SqtxgQ1qvD1ruRyQ6hGC1FLOY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81S26	uniprotkb:Q14192	intact:EBI-2811143|uniprotkb:Q6KU79|uniprotkb:Q6I0A5	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	psi-mi:ilvd_bacan(display_long)|uniprotkb:ilvD(gene name)|psi-mi:ilvD(display_short)|uniprotkb:BA_1853(locus name)|uniprotkb:GBAA_1853(locus name)|uniprotkb:BAS1717(locus name)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833802|imex:IM-13779-3808	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004404(Dihydroxy-acid dehydratase)|interpro:IPR000581(Dihydroxy-acid and 6-phosphogluconate dehydratase)|interpro:IPR020558|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004160""(dihydroxy-acid dehydratase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|refseq:WP_001255799.1|interpro:IPR037237|interpro:IPR042096|refseq:NP_844270.1|refseq:YP_027982.1"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:2rwY7biS4Is4mpOU8lcawsTzqSU1392	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:ED0BD6209922D819|rigid:TP/kTEgJADd71dpZHHsLlqX8BwY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7REH3	uniprotkb:Q14192	intact:EBI-2811064|uniprotkb:Q6KPV8|uniprotkb:E9R093|uniprotkb:Q81YE8	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	psi-mi:a0a0f7reh3_bacan(display_long)|uniprotkb:GBAA_3601(locus name)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833828|imex:IM-13779-3805	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_001116379.1|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR047589	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:kRV2TrznOHMKW2jOg5FKoFx9L+41392	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:CCFB9E4D7AEF260A|rigid:NvQ+qElOduqR5sqXqH1yGHUQ4kA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VT8	uniprotkb:Q14192	intact:EBI-2811891|uniprotkb:Q6I4U2	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833821|imex:IM-13779-3807	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:63C563209A19D437|rigid:PyCUl2b1yPqwnpKQlX/fbmGcC1M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A4Y1WAR4	uniprotkb:Q14192	intact:EBI-2832614|uniprotkb:Q6HR10|uniprotkb:Q6KKC9|uniprotkb:E9QY06|uniprotkb:E9QY07|uniprotkb:Q81X74|uniprotkb:A0A0J1HQ93|uniprotkb:A0A348AC26	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	psi-mi:a0a4y1war4_bacan(display_long)|uniprotkb:gap2(gene name)|psi-mi:gap2(display_short)|uniprotkb:GBAA_5369(locus name)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833835|imex:IM-13779-3806	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|refseq:WP_000161236.1|go:""GO:0002020""(protease binding)|go:""GO:0004365""(""glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"")|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0009986""(cell surface)|go:""GO:0016020""(membrane)|go:""GO:0044542""(symbiont-mediated activation of host plasminogen)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|interpro:IPR036291"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:0d8q3Y4FUwK4Iv4Qkl7Nic6MPFM1392	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:CC601DE39699EC35|rigid:rmApQO12+ww6K7IhQxu8PSIl+8o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14192	uniprotkb:A0A6L7HQR7	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	intact:EBI-2833812|uniprotkb:Q6I3F8|uniprotkb:Q6KX72|uniprotkb:E9QVX8|uniprotkb:E9QVX9|uniprotkb:A0A2P0H9Y8|uniprotkb:Q81V72	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:a0a6l7hqr7_bacan(display_long)|uniprotkb:GBAA_0628(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833809|imex:IM-13779-3804	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	interpro:IPR000160(GGDEF)|interpro:IPR001633(EAL)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR029787|refseq:WP_000893370.1|interpro:IPR035919|interpro:IPR035965|interpro:IPR043128|interpro:IPR052155	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	rogid:tJny9Y0pW3oKYIkIg6ovmEo7Bjo1392	intact-crc:B043FE042E56F147|rigid:Mm4Yfazt4yRFlwZpm0BRPn4a9sM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14192	uniprotkb:A0A6L7HPA8	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	intact:EBI-2816969|uniprotkb:Q6KKC5|uniprotkb:Q6HR06|uniprotkb:E9RBM9|uniprotkb:E9RBN0|uniprotkb:Q81X70|uniprotkb:A0A1J9WQB9|uniprotkb:A0A0J1KH94	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:a0a6l7hpa8_bacan(display_long)|uniprotkb:GBAA_5373(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833842|imex:IM-13779-3809	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	interpro:IPR012452(Protein of unknown function DUF1657)|refseq:WP_000216166.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	rogid:NNG8e4DHBu9NlSFjeq47wmv/1Ng1392	intact-crc:97CD73D5F649F9F4|rigid:z804Ubyi6jpKrS+65JnPsXhaTbs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0J1I358	uniprotkb:O15552	intact:EBI-2821852|uniprotkb:Q6KWE1|uniprotkb:E9RBM8|uniprotkb:Q81UC7|uniprotkb:A0A1Q4M286	intact:EBI-2833872|ensembl:ENSP00000246549.2|ensembl:ENSP00000473159.1|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5	psi-mi:a0a0j1i358_bacan(display_long)|uniprotkb:GBAA_0951(locus name)	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833869|imex:IM-13779-3811	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)"	"ensembl:ENSG00000126262.5(gene)|ensembl:ENST00000246549.2(transcript)|ensembl:ENST00000599180.3(transcript)|go:""GO:0002232""(leukocyte chemotaxis involved in inflammatory response)|go:""GO:0002385""(mucosal immune response)|go:""GO:0002673""(regulation of acute inflammatory response)|go:""GO:0002720""(positive regulation of cytokine production involved in immune response)|go:""GO:0002752""(cell surface pattern recognition receptor signaling pathway)|go:""GO:0002879""(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007200""(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:""GO:0008289""(lipid binding)|go:""GO:0019915""(lipid storage)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0042995""(cell projection)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0046676""(negative regulation of insulin secretion)|go:""GO:0071398""(cellular response to fatty acid)|go:""GO:0090276""(regulation of peptide hormone secretion)|go:""GO:1990806""(ligand-gated ion channel signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:8J22|rcsb pdb:8J23|rcsb pdb:8J24|rcsb pdb:8T3S|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1|refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|panther:PTHR45822(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XR+/9MNaW32SKRfjsv+IIpJBhVs1392	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	intact-crc:5FA6AA5F755852A2|rigid:KUOYLjX27nesK/Tj57OprmGgb7w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HC22	uniprotkb:P05230	intact:EBI-2833856|uniprotkb:Q6KYM0|uniprotkb:Q6I4X6|uniprotkb:E9RC54|uniprotkb:E9RC55|uniprotkb:Q81VX2|uniprotkb:A0A1S0QPD6	intact:EBI-698068|uniprotkb:P07502|uniprotkb:Q16588|uniprotkb:B2R5T0|uniprotkb:D3DQF2|ensembl:ENSP00000338548.2|ensembl:ENSP00000352329.6|ensembl:ENSP00000367285.1|ensembl:ENSP00000396195.2|ensembl:ENSP00000404742.2|ensembl:ENSP00000479024.1|ensembl:ENSP00000480791.1|ensembl:ENSP00000480980.1|ensembl:ENSP00000481868.1	psi-mi:a0a6l7hc22_bacan(display_long)|uniprotkb:cysK1(gene name)|psi-mi:cysK1(display_short)|uniprotkb:GBAA_0067(locus name)	psi-mi:fgf1_human(display_long)|uniprotkb:Acidic fibroblast growth factor(gene name synonym)|uniprotkb:FGF1(gene name)|psi-mi:FGF1(display_short)|uniprotkb:FGFA(gene name synonym)|uniprotkb:Heparin-binding growth factor 1(gene name synonym)|uniprotkb:Endothelial cell growth factor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833862|imex:IM-13779-3810	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0004124""(cysteine synthase activity)|go:""GO:0006535""(cysteine biosynthetic process from serine)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR005856(Cysteine synthase K/M)|interpro:IPR005859(Cysteine synthase A)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|refseq:WP_001261709.1|interpro:IPR036052|interpro:IPR050214"	"refseq:NP_000791.1|refseq:NP_001138364.1|refseq:NP_001138406.1|refseq:NP_001138407.1|refseq:NP_149127.1|refseq:NP_001244134.1|refseq:NP_001244136.1|refseq:NP_001244137.1|refseq:NP_001244138.1|refseq:NP_001244139.1|ensembl:ENSG00000113578.18(gene)|ensembl:ENST00000337706.7(transcript)|ensembl:ENST00000359370.10(transcript)|ensembl:ENST00000378046.5(transcript)|ensembl:ENST00000419524.6(transcript)|ensembl:ENST00000441680.6(transcript)|ensembl:ENST00000610990.4(transcript)|ensembl:ENST00000612258.4(transcript)|ensembl:ENST00000619447.4(transcript)|ensembl:ENST00000621536.4(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001759""(organ induction)|go:""GO:0005104""(fibroblast growth factor receptor binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007165""(signal transduction)|go:""GO:0008083""(growth factor activity)|go:""GO:0008201""(heparin binding)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008543""(fibroblast growth factor receptor signaling pathway)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0022008""(neurogenesis)|go:""GO:0030324""(lung development)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032148""(activation of protein kinase B activity)|go:""GO:0034605""(cellular response to heat)|go:""GO:0042060""(wound healing)|go:""GO:0043406""(positive regulation of MAP kinase activity)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0044548""(S100 protein binding)|go:""GO:0045542""(positive regulation of cholesterol biosynthetic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0051781""(positive regulation of cell division)|go:""GO:0060681""(branch elongation involved in ureteric bud branching)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0072163""(mesonephric epithelium development)|go:""GO:1901509""(regulation of endothelial tube morphogenesis)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:2000347""(positive regulation of hepatocyte proliferation)|go:""GO:2000544""(regulation of endothelial cell chemotaxis to fibroblast growth factor)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|mint:P05230|rcsb pdb:1AXM|rcsb pdb:1DJS|rcsb pdb:1DZC|rcsb pdb:1DZD|rcsb pdb:1E0O|rcsb pdb:1EVT|rcsb pdb:1HKN|rcsb pdb:1JQZ|rcsb pdb:1JT3|rcsb pdb:1JT4|rcsb pdb:1JT5|rcsb pdb:1JT7|rcsb pdb:1JTC|rcsb pdb:1JY0|rcsb pdb:1K5U|rcsb pdb:1K5V|rcsb pdb:1M16|rcsb pdb:1NZK|rcsb pdb:1P63|rcsb pdb:1PZZ|rcsb pdb:1Q03|rcsb pdb:1Q04|rcsb pdb:1RG8|rcsb pdb:1RML|rcsb pdb:1RY7|rcsb pdb:1YTO|rcsb pdb:1Z2V|rcsb pdb:1Z4S|rcsb pdb:2AFG|rcsb pdb:2AQZ|rcsb pdb:2AXM|rcsb pdb:2ERM|rcsb pdb:2HW9|rcsb pdb:2HWA|rcsb pdb:2HWM|rcsb pdb:2HZ9|rcsb pdb:2K43|rcsb pdb:2K4A|rcsb pdb:2K8R|rcsb pdb:2KI4|rcsb pdb:2KI6|rcsb pdb:2NTD|rcsb pdb:2Q9X|rcsb pdb:2RQ9|rcsb pdb:3B9U|rcsb pdb:3BA4|rcsb pdb:3BA5|rcsb pdb:3BA7|rcsb pdb:3BAD|rcsb pdb:3BAG|rcsb pdb:3BAH|rcsb pdb:3BAO|rcsb pdb:3BAQ|rcsb pdb:3BAU|rcsb pdb:3BAV|rcsb pdb:3BB2|rcsb pdb:3CQA|rcsb pdb:3CRG|rcsb pdb:3CRH|rcsb pdb:3CRI|rcsb pdb:3CU1|rcsb pdb:3FGM|rcsb pdb:3FJ8|rcsb pdb:3FJ9|rcsb pdb:3FJA|rcsb pdb:3FJB|rcsb pdb:3FJC|rcsb pdb:3FJD|rcsb pdb:3FJE|rcsb pdb:3FJF|rcsb pdb:3FJH|rcsb pdb:3FJI|rcsb pdb:3FJJ|rcsb pdb:3FJK|rcsb pdb:3HOM|rcsb pdb:3JUT|rcsb pdb:3K1X|rcsb pdb:3O3Q|rcsb pdb:3OJ2|rcsb pdb:3OJM|rcsb pdb:3OJV|rcsb pdb:3UD7|rcsb pdb:3UD8|rcsb pdb:3UD9|rcsb pdb:3UDA|rcsb pdb:4J23|rcsb pdb:4Q91|rcsb pdb:4Q9G|rcsb pdb:4Q9P|rcsb pdb:4QAL|rcsb pdb:4QBC|rcsb pdb:4QBV|rcsb pdb:4QC4|rcsb pdb:4QO3|rcsb pdb:4XKI|rcsb pdb:4YOL|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-1839122|reactome:R-HSA-1839130|reactome:R-HSA-190322|reactome:R-HSA-190370|reactome:R-HSA-190371|reactome:R-HSA-190372|reactome:R-HSA-190373|reactome:R-HSA-190375|reactome:R-HSA-190377|reactome:R-HSA-2033519|reactome:R-HSA-2219530|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5654687|reactome:R-HSA-5654688|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5655332|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851708|dip:DIP-3787N|panther:PTHR11486(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iDSZC/CjR3nV6smYOpIUKYYPVr41392	rogid:k1O8U8SRvl73sZ+J+gxmlUjAGow9606	intact-crc:7CC971D83388D134|rigid:XrfhqqSobvC9syLW7lTTccpguq8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WF0	uniprotkb:Q14192	intact:EBI-2820978|uniprotkb:Q6KNT3|uniprotkb:Q6HUJ8	intact:EBI-701903|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|ensembl:ENSP00000322909.8|ensembl:ENSP00000344266.5|ensembl:ENSP00000377020.3|ensembl:ENSP00000377021.3|ensembl:ENSP00000386633.1|ensembl:ENSP00000386665.1|ensembl:ENSP00000386892.3|ensembl:ENSP00000433567.2|uniprotkb:Q5TM15	psi-mi:pyrc_bacan(display_long)|uniprotkb:pyrC(gene name)|psi-mi:pyrC(display_short)|uniprotkb:BA_4027(locus name)|uniprotkb:GBAA_4027(locus name)|uniprotkb:BAS3739(locus name)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833849|imex:IM-13779-3812	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001108379.1|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR004722(Dihydroorotase multifunctional complex type)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR011059(Metal-dependent hydrolase, composite)|rcsb pdb:3MPG|go:""GO:0004038""(allantoinase activity)|go:""GO:0004151""(dihydroorotase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006145""(purine nucleobase catabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0044205""('de novo' UMP biosynthetic process)|rcsb pdb:4YIW|interpro:IPR032466|interpro:IPR050138|refseq:NP_846268.1|refseq:YP_029990.1"	"ensembl:ENSG00000115641.19(gene)|ensembl:ENST00000322142.13(transcript)|ensembl:ENST00000344213.9(transcript)|ensembl:ENST00000393352.7(transcript)|ensembl:ENST00000393353.7(transcript)|ensembl:ENST00000408995.5(transcript)|ensembl:ENST00000409177.6(transcript)|ensembl:ENST00000409807.5(transcript)|ensembl:ENST00000530340.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005925""(focal adhesion)|go:""GO:0008134""(transcription factor binding)|go:""GO:0009725""(response to hormone)|go:""GO:0030018""(Z disc)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0055014""(atrial cardiac muscle cell development)|go:""GO:0055015""(ventricular cardiac muscle cell development)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070885""(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|refseq:NP_001034581.1|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:XP_011509100.1|efo:""Orphanet:154""|dip:DIP-5980N|panther:PTHR24205(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:T44Z4wNvVgokSwycv3Ew0Dqc3ow1392	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:76EA122098FB59A9|rigid:1agxQIALFMqFmtvagG6Oybidrgc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8Q3J2	uniprotkb:P07332	intact:EBI-2824405|uniprotkb:Q6HWZ5|uniprotkb:Q6KR27|uniprotkb:E9QQT3|uniprotkb:E9QQT4|uniprotkb:Q81NS5|uniprotkb:A0A0F7RAF0	intact:EBI-1055635|ensembl:ENSP00000331504.3|uniprotkb:B4DUD0|uniprotkb:E9PC94|uniprotkb:E9PC95|uniprotkb:Q2VXS7|uniprotkb:Q2VXS8|uniprotkb:Q2VXT0|uniprotkb:Q6GTU5|uniprotkb:B2R6E6	psi-mi:a0a6l8q3j2_bacan(display_long)|uniprotkb:cutC(gene name)|psi-mi:cutC(display_short)|uniprotkb:GBAA_3100(locus name)	psi-mi:fes_human(display_long)|uniprotkb:FES(gene name)|psi-mi:FES(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:Proto-oncogene c-Fes(gene name synonym)|uniprotkb:Proto-oncogene c-Fps(gene name synonym)|uniprotkb:Feline sarcoma/Fujinami avian sarcoma oncogene homolog(gene name synonym)|uniprotkb:p93c-fes(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833884|imex:IM-13779-3813	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005627(CutC)|rcsb pdb:4R9X|go:""GO:0005507""(copper ion binding)|go:""GO:0005737""(cytoplasm)|interpro:IPR036822|refseq:WP_000895086.1"	"ensembl:ENSG00000182511.12(gene)|ensembl:ENST00000328850.8(transcript)|go:""GO:0001578""(microtubule bundle formation)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006935""(chemotaxis)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007155""(cell adhesion)|go:""GO:0008017""(microtubule binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0043304""(regulation of mast cell degranulation)|go:""GO:0045595""(regulation of cell differentiation)|go:""GO:0045639""(positive regulation of myeloid cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0051450""(myoblast proliferation)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0071305""(cellular response to vitamin D)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016250(Tyrosine-protein kinase, Fes/Fps)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027267|interpro:IPR031160|interpro:IPR035849|interpro:IPR036860|interpro:IPR050198|mint:P07332|rcsb pdb:1WQU|rcsb pdb:2DCR|rcsb pdb:3BKB|rcsb pdb:3CBL|rcsb pdb:3CD3|rcsb pdb:4DYL|rcsb pdb:4E93|rcsb pdb:6JMF|rcsb pdb:7T1K|rcsb pdb:7T1L|rcsb pdb:8X2T|reactome:R-HSA-1433557|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|refseq:NP_001137255.1|refseq:NP_001137256.1|refseq:NP_001137257.1|refseq:NP_001996.1|refseq:XP_005254937.1|refseq:XP_005254939.1|refseq:XP_016877494.1|refseq:XP_016877495.1|refseq:XP_016877496.1|refseq:XP_016877497.1|refseq:XP_016877498.1|refseq:XP_016877499.1|panther:PTHR24418(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/Hl6H8iEFWnVcF6xGjLoDRBmPQQ1392	rogid:jsI2Ytqu7whZlUt7qISAW3W3WqQ9606	intact-crc:8DA2C19774C3C0F1|rigid:xxiu/2Sjiam2KHurtV+V30aVg7c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9RMW6	uniprotkb:Q0JRZ9	intact:EBI-2833908|uniprotkb:Q7CM82|uniprotkb:A7M7D8	intact:EBI-2609756|uniprotkb:Q0JTJ3|uniprotkb:B2RNQ9|uniprotkb:A8K6W7|uniprotkb:Q96CF5|uniprotkb:B4DHK0|uniprotkb:E9PG79|ensembl:ENSP00000393776.2	psi-mi:y6593_bacan(display_long)|uniprotkb:pXO2-68(locus name)|uniprotkb:BXB0093(locus name)|uniprotkb:GBAA_pXO2_0093(locus name)	psi-mi:fcho2_human(display_long)|uniprotkb:FCHO2(gene name)|psi-mi:FCHO2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833905|imex:IM-13779-3817	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0003677""(DNA binding)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR009061(Putative DNA binding)|refseq:NP_053223.1|interpro:IPR025052|interpro:IPR000551(Bacterial regulatory protein, MerR)|refseq:WP_000908098.1"	"refseq:NP_001139504.1|refseq:NP_620137.2|ensembl:ENSG00000157107.14(gene)|ensembl:ENST00000430046.7(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0010324""(membrane invagination)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098793""(presynapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|interpro:IPR030122|interpro:IPR031160|interpro:IPR054713|mint:Q0JRZ9|rcsb pdb:2V0O|rcsb pdb:7OG1|rcsb pdb:7OHO|rcsb pdb:7OHZ|rcsb pdb:7OI5|rcsb pdb:7OIQ|rcsb pdb:7OIT|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-29488N|panther:PTHR23065(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wdK1VJAcnKpDrhcKaikA5PhLFhk1392	rogid:JYPt0L04ZvoacrpUFy49uFWxD489606	intact-crc:12EBFB199FA87787|rigid:urgVkBv0WtgbOYqJHEtkqpVLSNQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HNX5	uniprotkb:P07332	intact:EBI-2813143|uniprotkb:Q6KWX9|uniprotkb:Q6I360|uniprotkb:E9QY78|uniprotkb:E9QY79|uniprotkb:A0A2P0HA93|uniprotkb:Q81UX8	intact:EBI-1055635|ensembl:ENSP00000331504.3|uniprotkb:B4DUD0|uniprotkb:E9PC94|uniprotkb:E9PC95|uniprotkb:Q2VXS7|uniprotkb:Q2VXS8|uniprotkb:Q2VXT0|uniprotkb:Q6GTU5|uniprotkb:B2R6E6	psi-mi:a0a6l7hnx5_bacan(display_long)|uniprotkb:GBAA_0728(locus name)	psi-mi:fes_human(display_long)|uniprotkb:FES(gene name)|psi-mi:FES(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:Proto-oncogene c-Fes(gene name synonym)|uniprotkb:Proto-oncogene c-Fps(gene name synonym)|uniprotkb:Feline sarcoma/Fujinami avian sarcoma oncogene homolog(gene name synonym)|uniprotkb:p93c-fes(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833891|imex:IM-13779-3818	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015168(NMT1/THI5 like)|interpro:IPR027939|go:""GO:0009228""(thiamine biosynthetic process)|refseq:WP_000670426.1"	"ensembl:ENSG00000182511.12(gene)|ensembl:ENST00000328850.8(transcript)|go:""GO:0001578""(microtubule bundle formation)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006935""(chemotaxis)|go:""GO:0007098""(centrosome cycle)|go:""GO:0007155""(cell adhesion)|go:""GO:0008017""(microtubule binding)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0031116""(positive regulation of microtubule polymerization)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034987""(immunoglobulin receptor binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0043304""(regulation of mast cell degranulation)|go:""GO:0045595""(regulation of cell differentiation)|go:""GO:0045639""(positive regulation of myeloid cell differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0051450""(myoblast proliferation)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060627""(regulation of vesicle-mediated transport)|go:""GO:0071305""(cellular response to vitamin D)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:2000145""(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016250(Tyrosine-protein kinase, Fes/Fps)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027267|interpro:IPR031160|interpro:IPR035849|interpro:IPR036860|interpro:IPR050198|mint:P07332|rcsb pdb:1WQU|rcsb pdb:2DCR|rcsb pdb:3BKB|rcsb pdb:3CBL|rcsb pdb:3CD3|rcsb pdb:4DYL|rcsb pdb:4E93|rcsb pdb:6JMF|rcsb pdb:7T1K|rcsb pdb:7T1L|rcsb pdb:8X2T|reactome:R-HSA-1433557|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|refseq:NP_001137255.1|refseq:NP_001137256.1|refseq:NP_001137257.1|refseq:NP_001996.1|refseq:XP_005254937.1|refseq:XP_005254939.1|refseq:XP_016877494.1|refseq:XP_016877495.1|refseq:XP_016877496.1|refseq:XP_016877497.1|refseq:XP_016877498.1|refseq:XP_016877499.1|panther:PTHR24418(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EwiLGJeG/7Y619H/Meru5ccTc801392	rogid:jsI2Ytqu7whZlUt7qISAW3W3WqQ9606	intact-crc:539F4841D7629C72|rigid:frTjAJWN72AqzD1h6vmOWQhJxEQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HS72	uniprotkb:Q0JRZ9	intact:EBI-2813060|uniprotkb:Q6KYR5|uniprotkb:Q6I521|uniprotkb:E9R8F3|uniprotkb:E9R8F4|uniprotkb:Q81W18|uniprotkb:A0A0F7R3D8	intact:EBI-2609756|uniprotkb:Q0JTJ3|uniprotkb:B2RNQ9|uniprotkb:A8K6W7|uniprotkb:Q96CF5|uniprotkb:B4DHK0|uniprotkb:E9PG79|ensembl:ENSP00000393776.2	psi-mi:a0a6l7hs72_bacan(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:GBAA_0019(locus name)	psi-mi:fcho2_human(display_long)|uniprotkb:FCHO2(gene name)|psi-mi:FCHO2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833924|imex:IM-13779-3816	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR050238|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0009360""(DNA polymerase III complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_000121566.1|interpro:IPR045085"	"refseq:NP_001139504.1|refseq:NP_620137.2|ensembl:ENSG00000157107.14(gene)|ensembl:ENST00000430046.7(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0010324""(membrane invagination)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098793""(presynapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|interpro:IPR030122|interpro:IPR031160|interpro:IPR054713|mint:Q0JRZ9|rcsb pdb:2V0O|rcsb pdb:7OG1|rcsb pdb:7OHO|rcsb pdb:7OHZ|rcsb pdb:7OI5|rcsb pdb:7OIQ|rcsb pdb:7OIT|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-29488N|panther:PTHR23065(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gI03FuFZkZPgqwmAbFmVcuBiRWU1392	rogid:JYPt0L04ZvoacrpUFy49uFWxD489606	intact-crc:786B3F3DCE24981A|rigid:VVK/ttlj+n49Ed0NET7nC3Md3Ho	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0JRZ9	uniprotkb:Q81KK8	intact:EBI-2609756|uniprotkb:Q0JTJ3|uniprotkb:B2RNQ9|uniprotkb:A8K6W7|uniprotkb:Q96CF5|uniprotkb:B4DHK0|uniprotkb:E9PG79|ensembl:ENSP00000393776.2	intact:EBI-2822258|uniprotkb:Q6KLB4|uniprotkb:E9R5P7	psi-mi:fcho2_human(display_long)|uniprotkb:FCHO2(gene name)|psi-mi:FCHO2(display_short)	psi-mi:q81kk8_bacan(display_long)|uniprotkb:GBAA_4989(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833917|imex:IM-13779-3815	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001139504.1|refseq:NP_620137.2|ensembl:ENSG00000157107.14(gene)|ensembl:ENST00000430046.7(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0010324""(membrane invagination)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0048268""(clathrin coat assembly)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0072583""(clathrin-dependent endocytosis)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098793""(presynapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|interpro:IPR030122|interpro:IPR031160|interpro:IPR054713|mint:Q0JRZ9|rcsb pdb:2V0O|rcsb pdb:7OG1|rcsb pdb:7OHO|rcsb pdb:7OHZ|rcsb pdb:7OI5|rcsb pdb:7OIQ|rcsb pdb:7OIT|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-29488N|panther:PTHR23065(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JYPt0L04ZvoacrpUFy49uFWxD489606	rogid:IiAIRE+C5ddv3SFzgMBN5yxqO8Q1392	intact-crc:A6423617ED83D577|rigid:B32c7OGvsZa1F5tXwJ2UvzxaWfU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P4D1	uniprotkb:Q7L513	intact:EBI-2815551|uniprotkb:Q6KJT0|uniprotkb:Q6HQF5|uniprotkb:E9R395|uniprotkb:E9R396|uniprotkb:Q81JV4|uniprotkb:A0A0F7R924	intact:EBI-2806840|uniprotkb:Q5VXA1|uniprotkb:Q5VXA3|uniprotkb:Q5VXA2|uniprotkb:Q9BR57|uniprotkb:Q96PJ2|uniprotkb:Q96PJ0|uniprotkb:Q5VXA4|uniprotkb:Q8NEW4|uniprotkb:Q96PJ1|uniprotkb:Q8WXH3|uniprotkb:Q96PC6|uniprotkb:A0N0M1|uniprotkb:Q5VXB0|uniprotkb:Q96PJ4|ensembl:ENSP00000236938.7|uniprotkb:A6NC03|uniprotkb:A6NL20|uniprotkb:F5H720|uniprotkb:F8W743|uniprotkb:G3V1J2|uniprotkb:Q5VXB1	psi-mi:a0a6l8p4d1_bacan(display_long)|uniprotkb:GBAA_5590(locus name)	psi-mi:fcrla_human(display_long)|uniprotkb:FCRL(gene name synonym)|uniprotkb:FCRL1(gene name synonym)|uniprotkb:FCRLM1(gene name synonym)|uniprotkb:FCRX(gene name synonym)|uniprotkb:FREB(gene name synonym)|uniprotkb:Fc receptor homolog expressed in B-cells(gene name synonym)|uniprotkb:Fc receptor-like and mucin-like protein 1(gene name synonym)|uniprotkb:Fc receptor-like protein(gene name synonym)|uniprotkb:Fc receptor-related protein X(gene name synonym)|uniprotkb:UNQ291/PRO329(orf name)|uniprotkb:FCRLA(gene name)|psi-mi:FCRLA(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833898|imex:IM-13779-3814	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR004017(Cysteine-rich region, CCG)|go:""GO:0005886""(plasma membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR051460|refseq:WP_001086761.1|interpro:IPR036197|interpro:IPR009051(Alpha-helical ferredoxin)"	"refseq:NP_001171795.1|refseq:NP_001171796.1|refseq:NP_001171799.1|refseq:NP_001171800.1|refseq:NP_001171801.1|refseq:NP_001171802.1|refseq:NP_116127.3|ensembl:ENSG00000132185.18(gene)|ensembl:ENST00000236938.12(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0030154""(cell differentiation)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050488|rcsb pdb:4HWN|panther:PTHR11481(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6J4zBoBP0to2v+r4ugEhu0IrH5k1392	rogid:8IN4JYjINzn29PadL0irqR3sSeE9606	intact-crc:318AB72D62456B28|rigid:td4IL2FWakzfzTnF4b8SwEee4jw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HN52	uniprotkb:O75015	intact:EBI-2814703|uniprotkb:Q6I323|uniprotkb:Q6KWU3|uniprotkb:E9QRU5|uniprotkb:E9QRU6|uniprotkb:Q81UU1|uniprotkb:A0A0F7RLQ7	intact:EBI-2833945|ensembl:ENSP00000356941.2|ensembl:ENSP00000497461.1	psi-mi:a0a6l7hn52_bacan(display_long)|uniprotkb:spoVR(gene name)|psi-mi:spoVR(display_short)|uniprotkb:GBAA_0767(locus name)	psi-mi:fcg3b_human(display_long)|uniprotkb:FCGR3B(gene name)|psi-mi:FCGR3B(display_short)|uniprotkb:CD16B(gene name synonym)|uniprotkb:FCG3(gene name synonym)|uniprotkb:FCGR3(gene name synonym)|uniprotkb:IGFR3(gene name synonym)|uniprotkb:Fc-gamma RIII-beta(gene name synonym)|uniprotkb:FcR-10(gene name synonym)|uniprotkb:IgG Fc receptor III-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833949|imex:IM-13779-3821	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR007390(Sporulation stage V, protein R)|refseq:WP_001202722.1	"interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|ensembl:ENSG00000162747.13(gene)|ensembl:ENST00000367964.6(transcript)|ensembl:ENST00000650385.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0019770""(IgG receptor activity)|go:""GO:0019864""(IgG binding)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0034235""(GPI anchor binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR050488|rcsb pdb:1E4J|rcsb pdb:1E4K|rcsb pdb:1FNL|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:6EAQ|reactome:R-HSA-163125|reactome:R-HSA-6798695|refseq:NP_000561.3|refseq:NP_001231682.1|refseq:NP_001257964.1|refseq:NP_001257965.1|refseq:NP_001257966.1|efo:""Orphanet:464370""|efo:""Orphanet:536""|panther:PTHR11481(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CM2qh3zGYdstexV6ZdpNxbCtgPg1392	rogid:PZ73Ah2noRl/cRZNP5P4Rx5yxuo9606	intact-crc:BF549F4F286AAA6D|rigid:suJFMrwD7fl60ZnDeZYIhEUht+4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P55899	uniprotkb:A0A6L8P864	intact:EBI-2833934|ensembl:ENSP00000221466.4|ensembl:ENSP00000410798.2|uniprotkb:Q5HYM5|uniprotkb:Q9NZ19|uniprotkb:Q9HBV7	intact:EBI-2818016|uniprotkb:Q6I481|uniprotkb:Q6KXY7|uniprotkb:E9R899|uniprotkb:E9R8A0|uniprotkb:A0A2P0H999|uniprotkb:Q81ZD5	psi-mi:fcgrn_human(display_long)|uniprotkb:FCGRT(gene name)|psi-mi:FCGRT(display_short)|uniprotkb:FCRN(gene name synonym)|uniprotkb:IgG Fc fragment receptor transporter alpha chain(gene name synonym)|uniprotkb:Neonatal Fc receptor(gene name synonym)	psi-mi:a0a6l8p864_bacan(display_long)|uniprotkb:GBAA_0334(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833931|imex:IM-13779-3819	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000104870.13(gene)|ensembl:ENST00000221466.10(transcript)|ensembl:ENST00000426395.7(transcript)|go:""GO:0002416""(IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor)|go:""GO:0005615""(extracellular space)|go:""GO:0006955""(immune response)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0019864""(IgG binding)|go:""GO:0030881""(beta-2-microglobulin binding)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|interpro:IPR050208|mint:P55899|rcsb pdb:1EXU|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:4K71|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:5BJT|rcsb pdb:5BXF|rcsb pdb:5WHK|rcsb pdb:6C97|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6FGB|rcsb pdb:6ILM|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6NHA|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6WNA|rcsb pdb:6WOL|rcsb pdb:7B5F|rcsb pdb:7C9V|rcsb pdb:7Q15|rcsb pdb:7XXA|refseq:NP_001129491.1|refseq:NP_004098.1|dip:DIP-6165N|panther:PTHR16675(orthology-group)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR001269(Dihydrouridine synthase, DuS)|interpro:IPR018517|interpro:IPR024036|go:""GO:0000049""(tRNA binding)|go:""GO:0017150""(tRNA dihydrouridine synthase activity)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_000566690.1|interpro:IPR035587"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:o8At2wvcZMx6hLg5Zcih925vCa89606	rogid:Ws2lbrRnpZcDQtnDQAA8PqhrQ641392	intact-crc:366C737DF994C1FD|rigid:VuL9aTZNLyMjoe6x2uSUWltVq3o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08637	uniprotkb:A0A6L7H5N1	intact:EBI-2833956|ensembl:ENSP00000356944.3|ensembl:ENSP00000392047.2|ensembl:ENSP00000416607.1|ensembl:ENSP00000514356.1|ensembl:ENSP00000514357.1|ensembl:ENSP00000514358.1|uniprotkb:Q6PIJ0|uniprotkb:Q53FL6|uniprotkb:A2N6W9|uniprotkb:Q5EBR4|uniprotkb:Q65ZM6|uniprotkb:Q53FJ0	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:fcg3a_human(display_long)|uniprotkb:FCGR3A(gene name)|psi-mi:FCGR3A(display_short)|uniprotkb:CD16A(gene name synonym)|uniprotkb:FCG3(gene name synonym)|uniprotkb:FCGR3(gene name synonym)|uniprotkb:IGFR3(gene name synonym)|uniprotkb:CD16a antigen(gene name synonym)|uniprotkb:Fc-gamma RIII-alpha(gene name synonym)|uniprotkb:FcR-10(gene name synonym)|uniprotkb:IgG Fc receptor III-2(gene name synonym)|uniprotkb:CD16-II(gene name synonym)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833966|imex:IM-13779-3822	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000203747.13(gene)|ensembl:ENST00000367967.8(transcript)|ensembl:ENST00000436743.7(transcript)|ensembl:ENST00000443193.6(transcript)|ensembl:ENST00000699395.1(transcript)|ensembl:ENST00000699396.1(transcript)|ensembl:ENST00000699397.1(transcript)|go:""GO:0001788""(antibody-dependent cellular cytotoxicity)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0019770""(IgG receptor activity)|go:""GO:0019772""(low-affinity IgG receptor activity)|go:""GO:0019864""(IgG binding)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032819""(positive regulation of natural killer cell proliferation)|go:""GO:0033001""(Fc-gamma receptor III complex)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0042116""(macrophage activation)|go:""GO:0042267""(natural killer cell mediated cytotoxicity)|go:""GO:0043320""(natural killer cell degranulation)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0070062""(extracellular exosome)|go:""GO:0140375""(immune receptor activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050488|mint:P08637|rcsb pdb:3AY4|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3WN5|rcsb pdb:5BW7|rcsb pdb:5D6D|rcsb pdb:5ML9|rcsb pdb:5MN2|rcsb pdb:5VU0|rcsb pdb:5XJE|rcsb pdb:5XJF|rcsb pdb:5YC5|rcsb pdb:7SEG|rcsb pdb:7URU|reactome:R-HSA-198933|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-9664323|reactome:R-HSA-9664422|refseq:NP_000560.6|refseq:NP_001121064.2|refseq:NP_001121065.1|refseq:NP_001121067.1|refseq:NP_001121068.1|refseq:NP_001316049.1|efo:""Orphanet:437552""|panther:PTHR11481(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qnL5hzgVCJeoN2OBxQCpXJxH/tE9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:981DAC5DA6F4BA76|rigid:F8orOg0wVYFD2JOWDo40+VEdONM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30273	uniprotkb:A0A6H3A8H6	intact:EBI-515289|uniprotkb:Q5VTW4|ensembl:ENSP00000289902.1	intact:EBI-2819804|uniprotkb:Q6KK02|uniprotkb:Q6HQM9|uniprotkb:E9QXJ8|uniprotkb:E9QXJ9|uniprotkb:Q81K29	psi-mi:fcerg_human(display_long)|uniprotkb:IgE Fc receptor subunit gamma(gene name synonym)|uniprotkb:Fc-epsilon RI-gamma(gene name synonym)|uniprotkb:FCER1G(gene name)|psi-mi:FCER1G(display_short)|uniprotkb:Fc receptor gamma-chain(gene name synonym)	psi-mi:a0a6h3a8h6_bacan(display_long)|uniprotkb:GBAA_5512(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833973|imex:IM-13779-3820	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004097.1|ensembl:ENSG00000158869.11(gene)|ensembl:ENST00000289902.2(transcript)|go:""GO:0002283""(neutrophil activation involved in immune response)|go:""GO:0002292""(T cell differentiation involved in immune response)|go:""GO:0002431""(Fc receptor mediated stimulatory signaling pathway)|go:""GO:0005886""(plasma membrane)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010543""(regulation of platelet activation)|go:""GO:0016064""(immunoglobulin mediated immune response)|go:""GO:0019767""(IgE receptor activity)|go:""GO:0019863""(IgE binding)|go:""GO:0019864""(IgG binding)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0030593""(neutrophil chemotaxis)|go:""GO:0031623""(receptor internalization)|go:""GO:0032753""(positive regulation of interleukin-4 production)|go:""GO:0032998""(Fc-epsilon receptor I complex)|go:""GO:0033001""(Fc-gamma receptor III complex)|go:""GO:0038094""(Fc-gamma receptor signaling pathway)|go:""GO:0038095""(Fc-epsilon receptor signaling pathway)|go:""GO:0038156""(interleukin-3-mediated signaling pathway)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045087""(innate immune response)|go:""GO:0050766""(positive regulation of phagocytosis)|go:""GO:0070821""(tertiary granule membrane)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0101003""(ficolin-1-rich granule membrane)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR042340|mint:P30273|rcsb pdb:7Q5T|reactome:R-HSA-114604|reactome:R-HSA-202733|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5621480|reactome:R-HSA-6798695|reactome:R-HSA-75892|dip:DIP-29514N|panther:PTHR16803(orthology-group)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR028359|go:""GO:0000271""(polysaccharide biosynthetic process)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0016628""(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)|go:""GO:0051287""(NAD binding)|refseq:WP_000686704.1|interpro:IPR036220|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sYW44kyg+jmeUmR9vWSSPdyq4N49606	rogid:92IMzy8A8WHQnwQ4Gph/NMcJOI01392	intact-crc:97E801E7E84CEC2F|rigid:xaO4oSGwIdbG8a09pt7I5a51guM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NYY8	uniprotkb:A0A6L8PN40	intact:EBI-1055752|uniprotkb:Q9NVX6|uniprotkb:Q9Y2H7|ensembl:ENSP00000236980.6|ensembl:ENSP00000384929.3|ensembl:ENSP00000385990.3|intact:EBI-21354662	intact:EBI-2809979|uniprotkb:Q6KX48|uniprotkb:Q6I3D2|uniprotkb:E9QZ41|uniprotkb:E9QZ42|uniprotkb:Q81V48|uniprotkb:A0A0F7RLX2	psi-mi:fakd2_human(display_long)|uniprotkb:FASTKD2(gene name)|psi-mi:FASTKD2(display_short)|uniprotkb:KIAA0971(gene name synonym)	psi-mi:a0a6l8pn40_bacan(display_long)|uniprotkb:GBAA_0653(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834014|imex:IM-13779-3827	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000118246.14(gene)|ensembl:ENST00000236980.10(transcript)|ensembl:ENST00000402774.8(transcript)|ensembl:ENST00000403094.3(transcript)|go:""GO:0000963""(mitochondrial RNA processing)|go:""GO:0003723""(RNA binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006396""(RNA processing)|go:""GO:0006915""(apoptotic process)|go:""GO:0019843""(rRNA binding)|go:""GO:0032543""(mitochondrial translation)|go:""GO:0035770""(ribonucleoprotein granule)|go:""GO:0042645""(mitochondrial nucleoid)|go:""GO:0044528""(regulation of mitochondrial mRNA stability)|go:""GO:0070131""(positive regulation of mitochondrial translation)|go:""GO:1902775""(mitochondrial large ribosomal subunit assembly)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|interpro:IPR050870|mint:Q9NYY8|reactome:R-HSA-9837092|refseq:NP_001129665.1|refseq:NP_001129666.1|refseq:NP_055744.2|efo:""Orphanet:166105""|panther:PTHR21228(orthology-group)"	"interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR052706|go:""GO:0016020""(membrane)|interpro:IPR036513|refseq:WP_000487882.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:b7H58ZWEhq5IFl+wO3fsez1v+1U9606	rogid:uXxKvpa5urYCow1J6WlFTe4Oxoo1392	intact-crc:3A32C8CF22440895|rigid:7tKBxEQPKq3YhJ3v5B0C8ZCosgs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35555	uniprotkb:Q6F011	intact:EBI-2505934|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6|ensembl:ENSP00000325527.5	intact:EBI-2823298|uniprotkb:A0A0F7RIB2	psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym)	psi-mi:q6f011_bacan(display_long)|uniprotkb:GBAA_pXO1_0005(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833993|imex:IM-13779-3826	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1885""|efo:""Orphanet:2084""|efo:""Orphanet:2462""|efo:""Orphanet:2623""|efo:""Orphanet:2833""|efo:""Orphanet:284963""|efo:""Orphanet:284979""|efo:""Orphanet:300382""|efo:""Orphanet:3449""|efo:""Orphanet:91387""|efo:""Orphanet:969""|dip:DIP-29985N|ensembl:ENSG00000166147.16(gene)|ensembl:ENST00000316623.10(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001527""(microfibril)|go:""GO:0001656""(metanephros development)|go:""GO:0005178""(integrin binding)|go:""GO:0005179""(hormone activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010467""(gene expression)|go:""GO:0030023""(extracellular matrix constituent conferring elasticity)|go:""GO:0031012""(extracellular matrix)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035582""(sequestering of BMP in extracellular matrix)|go:""GO:0035583""(sequestering of TGFbeta in extracellular matrix)|go:""GO:0042802""(identical protein binding)|go:""GO:0043010""(camera-type eye development)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0048286""(lung alveolus development)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:1990314""(cellular response to insulin-like growth factor stimulus)|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|interpro:IPR049388|interpro:IPR049883|interpro:IPR052080|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|panther:PTHR24039(orthology-group)"	refseq:WP_000916417.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606	rogid:yZD9hdclUepAZ0ePS1LmfAgcLmI1392	intact-crc:8A8923944B567FC4|rigid:Q2IZwJGLk6dpWVN6xXTpuoE/UNY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12805	uniprotkb:Q81TL8	intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|uniprotkb:B4DW75|ensembl:ENSP00000347596.3|ensembl:ENSP00000378058.2	intact:EBI-2810855|uniprotkb:Q6KVP0|uniprotkb:Q6I1U8	psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym)	psi-mi:trpb_bacan(display_long)|uniprotkb:trpB(gene name)|psi-mi:trpB(display_short)|uniprotkb:BA_1253(locus name)|uniprotkb:GBAA_1253(locus name)|uniprotkb:BAS1161(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834007|imex:IM-13779-3825	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR24039(orthology-group)|ensembl:ENSG00000115380.20(gene)|ensembl:ENST00000355426.8(transcript)|ensembl:ENST00000394555.6(transcript)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005154""(epidermal growth factor receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007601""(visual perception)|go:""GO:0008083""(growth factor activity)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0032331""(negative regulation of chondrocyte differentiation)|go:""GO:0043010""(camera-type eye development)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1|efo:""Orphanet:75376""|efo:""Orphanet:98977"""	"rcsb pdb:4NEG|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR006653(Tryptophan synthase, beta chain, conserved site)|interpro:IPR006654(Tryptophan synthase, beta chain)|interpro:IPR023026|go:""GO:0004834""(tryptophan synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006568""(L-tryptophan metabolic process)|refseq:WP_001105001.1|interpro:IPR036052|refseq:NP_843725.1|refseq:YP_027432.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606	rogid:8bGGwe6QiCJpPhUQlmDzddcdDJc1392	intact-crc:C6C456D7894D32DC|rigid:o4+jZzdO9QahGcYSPziJQqgKjYE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P35555	uniprotkb:A0A6L8NX76	intact:EBI-2505934|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6|ensembl:ENSP00000325527.5	intact:EBI-2833980|uniprotkb:Q6HSY5|uniprotkb:Q6KM73|uniprotkb:E9QZB4|uniprotkb:E9QZB5|uniprotkb:Q81LH8|uniprotkb:A0A0F7RD06	psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym)	psi-mi:a0a6l8nx76_bacan(display_long)|uniprotkb:secDF(gene name)|psi-mi:secDF(display_short)|uniprotkb:secD(gene name synonym)|uniprotkb:secF(gene name synonym)|uniprotkb:GBAA_4641(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2833986|imex:IM-13779-3823	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1885""|efo:""Orphanet:2084""|efo:""Orphanet:2462""|efo:""Orphanet:2623""|efo:""Orphanet:2833""|efo:""Orphanet:284963""|efo:""Orphanet:284979""|efo:""Orphanet:300382""|efo:""Orphanet:3449""|efo:""Orphanet:91387""|efo:""Orphanet:969""|dip:DIP-29985N|ensembl:ENSG00000166147.16(gene)|ensembl:ENST00000316623.10(transcript)|go:""GO:0001501""(skeletal system development)|go:""GO:0001527""(microfibril)|go:""GO:0001656""(metanephros development)|go:""GO:0005178""(integrin binding)|go:""GO:0005179""(hormone activity)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0005615""(extracellular space)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0007507""(heart development)|go:""GO:0008201""(heparin binding)|go:""GO:0009653""(anatomical structure morphogenesis)|go:""GO:0010467""(gene expression)|go:""GO:0030023""(extracellular matrix constituent conferring elasticity)|go:""GO:0031012""(extracellular matrix)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0035582""(sequestering of BMP in extracellular matrix)|go:""GO:0035583""(sequestering of TGFbeta in extracellular matrix)|go:""GO:0042802""(identical protein binding)|go:""GO:0043010""(camera-type eye development)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0048048""(embryonic eye morphogenesis)|go:""GO:0048050""(post-embryonic eye morphogenesis)|go:""GO:0048286""(lung alveolus development)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:1990314""(cellular response to insulin-like growth factor stimulus)|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|interpro:IPR049388|interpro:IPR049883|interpro:IPR052080|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-2173789|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|panther:PTHR24039(orthology-group)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0015450""(protein-transporting ATPase activity)|go:""GO:0043952""(protein transport by the Sec complex)|go:""GO:0065002""(intracellular protein transmembrane transport)|interpro:IPR048631|interpro:IPR048634|interpro:IPR005791(SecD export membrane protein)|interpro:IPR022813|interpro:IPR022646|interpro:IPR022645|interpro:IPR005665(SecF protein)|refseq:WP_001119062.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606	rogid:njkioqoOuOon02vz9WhpdXjLRII1392	intact-crc:433E1D9849128A87|rigid:kkOsc/hxrE3yz4hHLlBheN2mOYM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7RJB0	uniprotkb:O95967	intact:EBI-2827435|uniprotkb:Q6KXD7|uniprotkb:Q6I3M5|uniprotkb:E9R4B4|uniprotkb:E9R4B5|uniprotkb:Q81YS3	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953.6|ensembl:ENSP00000435295.1	psi-mi:a0a0f7rjb0_bacan(display_long)|uniprotkb:GBAA_0559(locus name)	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834000|imex:IM-13779-3824	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033463|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR016120(Signal transduction histidine kinase, sporulation regulator SpoOB)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR029151|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR035965|interpro:IPR036890"	"efo:""Orphanet:314718""|efo:""Orphanet:90349""|dip:DIP-34518N|ensembl:ENSG00000172638.13(gene)|ensembl:ENST00000307998.11(transcript)|ensembl:ENST00000531972.5(transcript)|go:""GO:0001527""(microfibril)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005604""(basement membrane)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0035904""(aorta development)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0060414""(aorta smooth muscle tissue morphogenesis)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071953""(elastic fiber)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904026""(regulation of collagen fibril organization)|go:""GO:1904028""(positive regulation of collagen fibril organization)|go:""GO:1904706""(negative regulation of vascular associated smooth muscle cell proliferation)|go:""GO:1904831""(positive regulation of aortic smooth muscle cell differentiation)|go:""GO:1905609""(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052235|interpro:IPR055088|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|refseq:NP_058634.4|panther:PTHR24034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QcoG1KEllnFAc5AsQKGhgB/IrHU1392	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	intact-crc:F7D5754FB70F74D3|rigid:QzevqYNcQOzJYGfk/gIismjicJw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5RI15	uniprotkb:A0A2P0HDE6	intact:EBI-2834035|uniprotkb:Q8WV86|ensembl:ENSP00000406327.2	intact:EBI-2817611|uniprotkb:Q6KTI8|uniprotkb:E9RCS0|uniprotkb:Q81RC4	psi-mi:cox20_human(display_long)|uniprotkb:COX20(gene name)|psi-mi:COX20(display_short)|uniprotkb:FAM36A(gene name synonym)	psi-mi:a0a2p0hde6_bacan(display_long)|uniprotkb:narG(gene name)|psi-mi:narG(display_short)|uniprotkb:GBAA_2125(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834040|imex:IM-13779-3831	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:254905""|ensembl:ENSG00000203667.10(gene)|ensembl:ENST00000411948.7(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0033617""(mitochondrial cytochrome c oxidase assembly)|interpro:IPR022533|mint:Q5RI15|reactome:R-HSA-9864848|refseq:NP_001299800.1|refseq:NP_932342.1|panther:PTHR31586(orthology-group)"	"refseq:WP_000729072.1|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006468(Nitrate reductase, alpha subunit)|interpro:IPR027467|interpro:IPR028189|go:""GO:0005886""(plasma membrane)|go:""GO:0009325""(nitrate reductase complex)|go:""GO:0042128""(nitrate assimilation)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0160182""(""nitrate reductase (quinone) activity"")|interpro:IPR050123|interpro:IPR037943|interpro:IPR044906"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aEzOHrwpeXm+HutVUkXznyZci7k9606	rogid:k5Zv8sx/0pTwM+d5PJb/SyjfYeY1392	intact-crc:07F6023446E3C38D|rigid:3uhLIf5qPc7tvzUSPVTCF3cyFTo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UNN5	uniprotkb:A0A2B6BPR1	intact:EBI-718246|uniprotkb:Q9UF34|uniprotkb:Q9UNT3|uniprotkb:Q9Y2Z3|ensembl:ENSP00000379457.2|uniprotkb:Q549F0	intact:EBI-2813910|uniprotkb:Q6KKM0|uniprotkb:E9R1B4|uniprotkb:Q81XH0|uniprotkb:A0A1Q4LXS8	psi-mi:faf1_human(display_long)|uniprotkb:FAF1(gene name)|psi-mi:FAF1(display_short)|uniprotkb:CGI-03(orf name)|uniprotkb:UBXD12(gene name synonym)|uniprotkb:UBXN3A(gene name synonym)|uniprotkb:UBX domain-containing protein 3A(gene name synonym)|uniprotkb:UBX domain-containing protein 12(gene name synonym)	psi-mi:a0a2b6bpr1_bacan(display_long)|uniprotkb:GBAA_5267(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834021|imex:IM-13779-3832	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_008982.1|ensembl:ENSG00000185104.21(gene)|ensembl:ENST00000396153.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0007253""(obsolete cytoplasmic sequestering of NF-kappaB)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034098""(VCP-NPL4-UFD1 AAA ATPase complex)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042176""(regulation of protein catabolic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:1902043""(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1990917""(ooplasm)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR033043|interpro:IPR036249|interpro:IPR044541|interpro:IPR049483|interpro:IPR050730|mint:Q9UNN5|rcsb pdb:1H8C|rcsb pdb:2DZM|rcsb pdb:2EC4|rcsb pdb:3E21|rcsb pdb:3QC8|rcsb pdb:3QCA|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3QX1|rcsb pdb:3R3M|rcsb pdb:7FGM|rcsb pdb:7FGN|rcsb pdb:8KG2|dip:DIP-38245N|panther:PTHR23322(orthology-group)"	"interpro:IPR025053|go:""GO:0016020""(membrane)|refseq:WP_000404786.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jYlrz7+swvye+qZ/6F4yTv74wLI9606	rogid:dnWJqU9FbVLV37uMd/n/DT7J4yg1392	intact-crc:555D4FCFA599B0D1|rigid:KIm6asiF4MMzQwsuPEXCgu6QrJg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13158	uniprotkb:A0A6L8PF45	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	intact:EBI-2831641|uniprotkb:Q6HRU1|uniprotkb:Q6KL49|uniprotkb:E9QWT9|uniprotkb:E9QWU0|uniprotkb:Q81KD6|uniprotkb:A0A0F7RAL5	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	psi-mi:a0a6l8pf45_bacan(display_long)|uniprotkb:feoB(gene name)|psi-mi:feoB(display_short)|uniprotkb:GBAA_5064(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834054|imex:IM-13779-3830	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	"interpro:IPR041069|interpro:IPR003373(Ferrous iron transport protein B)|interpro:IPR011640(Ferrous iron transport B, C-terminal)|interpro:IPR011642(Nucleoside recognition)|interpro:IPR006073(GTP1/OBG)|refseq:WP_001044820.1|interpro:IPR027417|interpro:IPR030389|go:""GO:0005525""(GTP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0015093""(ferrous iron transmembrane transporter activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR050860"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/06	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	rogid:9jQwZ4i974wMzbx5LReh2SXlhWE1392	intact-crc:98D063EC1AD76B8C|rigid:m1q2E/Ba7ZQYRYc1QE/ucj2BAi4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q13158	uniprotkb:Q9X2Y7	intact:EBI-494804|uniprotkb:Q14866|uniprotkb:Q6IBR4|ensembl:ENSP00000301838.5	intact:EBI-2822426|uniprotkb:A0A0F7RMV6	psi-mi:fadd_human(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:FADD(gene name)|psi-mi:FADD(display_short)|uniprotkb:MORT1(gene name synonym)|uniprotkb:GIG3(orf name)|uniprotkb:Growth-inhibiting gene 3 protein(gene name synonym)	psi-mi:q9x2y7_bacan(display_long)|uniprotkb:GBAA_pXO1_0023(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834028|imex:IM-13779-3828	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:306550""|efo:""Orphanet:99806""|ensembl:ENSG00000168040.5(gene)|ensembl:ENST00000301838.5(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002020""(protease binding)|go:""GO:0002821""(positive regulation of adaptive immune response)|go:""GO:0005123""(death receptor binding)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0008625""(extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0031264""(death-inducing signaling complex)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032813""(tumor necrosis factor receptor superfamily binding)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0033612""(receptor serine/threonine kinase binding)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035877""(death effector domain binding)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042104""(positive regulation of activated T cell proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0044297""(cell body)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0045651""(positive regulation of macrophage differentiation)|go:""GO:0045862""(positive regulation of proteolysis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048148""(behavioral response to cocaine)|go:""GO:0048535""(lymph node development)|go:""GO:0048536""(spleen development)|go:""GO:0048538""(thymus development)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0070236""(negative regulation of activation-induced cell death of T cells)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071550""(death-inducing signaling complex assembly)|go:""GO:0089720""(caspase binding)|go:""GO:0097049""(motor neuron apoptotic process)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097192""(extrinsic apoptotic signaling pathway in absence of ligand)|go:""GO:0097202""(obsolete activation of cysteine-type endopeptidase activity)|go:""GO:0097342""(ripoptosome)|go:""GO:0097527""(necroptotic signaling pathway)|go:""GO:1900119""(positive regulation of execution phase of apoptosis)|go:""GO:2000454""(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|interpro:IPR049634|mint:Q13158|rcsb pdb:1A1W|rcsb pdb:1A1Z|rcsb pdb:1E3Y|rcsb pdb:1E41|rcsb pdb:2GF5|rcsb pdb:3EZQ|rcsb pdb:3OQ9|rcsb pdb:6ACI|rcsb pdb:7LXC|rcsb pdb:8YBX|rcsb pdb:8YD7|rcsb pdb:8YD8|reactome:R-HSA-140534|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9693928|refseq:NP_003815.1|dip:DIP-286N|panther:PTHR15077(orthology-group)|ensembl:ENSP00000301838.5"	refseq:NP_052712.1|refseq:WP_000520265.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/06	rogid:DzaWyJjHDsNt8nMWLbv6GYa0Ri49606	rogid:C/Dv2F3mwNIZHsyvqckTtrgj5JI1392	intact-crc:35D9B218FA952ED3|rigid:/eAINR3tDtmQUS2jniOS0WZxRv8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UNN5	uniprotkb:A0A6L8PC29	intact:EBI-718246|uniprotkb:Q9UF34|uniprotkb:Q9UNT3|uniprotkb:Q9Y2Z3|ensembl:ENSP00000379457.2|uniprotkb:Q549F0	intact:EBI-2810801|uniprotkb:Q6KRM4|uniprotkb:Q6HXJ8|uniprotkb:E9QRE3|uniprotkb:E9QRE4|uniprotkb:A0A2P0HF49|uniprotkb:Q81PD4	psi-mi:faf1_human(display_long)|uniprotkb:FAF1(gene name)|psi-mi:FAF1(display_short)|uniprotkb:CGI-03(orf name)|uniprotkb:UBXD12(gene name synonym)|uniprotkb:UBXN3A(gene name synonym)|uniprotkb:UBX domain-containing protein 3A(gene name synonym)|uniprotkb:UBX domain-containing protein 12(gene name synonym)	psi-mi:a0a6l8pc29_bacan(display_long)|uniprotkb:GBAA_2876(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834047|imex:IM-13779-3829	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_008982.1|ensembl:ENSG00000185104.21(gene)|ensembl:ENST00000396153.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0007253""(obsolete cytoplasmic sequestering of NF-kappaB)|go:""GO:0019887""(protein kinase regulator activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031265""(CD95 death-inducing signaling complex)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0034098""(VCP-NPL4-UFD1 AAA ATPase complex)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042176""(regulation of protein catabolic process)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:1902043""(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1990917""(ooplasm)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR033043|interpro:IPR036249|interpro:IPR044541|interpro:IPR049483|interpro:IPR050730|mint:Q9UNN5|rcsb pdb:1H8C|rcsb pdb:2DZM|rcsb pdb:2EC4|rcsb pdb:3E21|rcsb pdb:3QC8|rcsb pdb:3QCA|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3QX1|rcsb pdb:3R3M|rcsb pdb:7FGM|rcsb pdb:7FGN|rcsb pdb:8KG2|dip:DIP-38245N|panther:PTHR23322(orthology-group)"	refseq:WP_001062740.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jYlrz7+swvye+qZ/6F4yTv74wLI9606	rogid:4BbTj8554Gwm4rVypGL1Pva9DGE1392	intact-crc:567F67FE9AC64BFE|rigid:hbDSPFvzisfrAr8SEL3vLFlxGKM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16875	uniprotkb:A0A6L7HB40	intact:EBI-764464|uniprotkb:Q5VX18|uniprotkb:O43622|uniprotkb:O75902|intact:EBI-2834088|uniprotkb:Q5VX19|uniprotkb:B7Z955|ensembl:ENSP00000369100.4|uniprotkb:Q5VX15	intact:EBI-2812761|uniprotkb:Q6I3J5|uniprotkb:Q6KXA8|uniprotkb:E9R2F8|uniprotkb:E9R2F9|uniprotkb:A0A2P0H9V3|uniprotkb:Q81VA8	psi-mi:f263_human(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme(gene name synonym)|uniprotkb:iPFK-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-56(gene name synonym)|uniprotkb:PFKFB3(gene name)|psi-mi:PFKFB3(display_short)	psi-mi:a0a6l7hb40_bacan(display_long)|uniprotkb:GBAA_0589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834095|imex:IM-13779-3834	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004557.1|refseq:NP_001269559.1|ensembl:ENSG00000170525.21(gene)|ensembl:ENST00000379775.9(transcript)|go:""GO:0003873""(6-phosphofructo-2-kinase activity)|go:""GO:0004331""(fructose-2,6-bisphosphate 2-phosphatase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006000""(fructose metabolic process)|go:""GO:0006003""(fructose 2,6-bisphosphate metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0010001""(glial cell differentiation)|go:""GO:0061744""(motor behavior)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|mint:Q16875|rcsb pdb:2AXN|rcsb pdb:2DWO|rcsb pdb:2DWP|rcsb pdb:2I1V|rcsb pdb:3QPU|rcsb pdb:3QPV|rcsb pdb:3QPW|rcsb pdb:4D4J|rcsb pdb:4D4K|rcsb pdb:4D4L|rcsb pdb:4D4M|rcsb pdb:4MA4|rcsb pdb:5AJV|rcsb pdb:5AJW|rcsb pdb:5AJX|rcsb pdb:5AJY|rcsb pdb:5AJZ|rcsb pdb:5AK0|rcsb pdb:6ETJ|rcsb pdb:6HVH|rcsb pdb:6HVI|rcsb pdb:6HVJ|rcsb pdb:6IBX|rcsb pdb:6IBY|rcsb pdb:6IBZ|rcsb pdb:6IC0|reactome:R-HSA-9634600|refseq:NP_001300992.1|dip:DIP-33964N|panther:PTHR10606(orthology-group)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR001041(Ferredoxin)|interpro:IPR006478(Formate dehydrogenase, alpha subunit)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR019574|interpro:IPR050123|interpro:IPR027467|go:""GO:0003954""(NADH dehydrogenase activity)|go:""GO:0008863""(""formate dehydrogenase (NAD+) activity"")|go:""GO:0015942""(formate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_000840648.1|interpro:IPR036010|interpro:IPR041924"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:BPxZYy35rU3GFHZ0+i9FpfTQh9s9606	rogid:QNDnbGYfnNxnQEMZtqgLWO6/cVs1392	intact-crc:D78AE2C889BC8B62|rigid:tRxuLI4/WOso4nxf7MLdkkK7tEs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16875	uniprotkb:A0A4Y1WDN0	intact:EBI-764464|uniprotkb:Q5VX18|uniprotkb:O43622|uniprotkb:O75902|intact:EBI-2834088|uniprotkb:Q5VX19|uniprotkb:B7Z955|ensembl:ENSP00000369100.4|uniprotkb:Q5VX15	intact:EBI-2820076|uniprotkb:Q6KJS1|uniprotkb:E9QTT6|uniprotkb:Q81JU4	psi-mi:f263_human(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme(gene name synonym)|uniprotkb:iPFK-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-56(gene name synonym)|uniprotkb:PFKFB3(gene name)|psi-mi:PFKFB3(display_short)	psi-mi:a0a4y1wdn0_bacan(display_long)|uniprotkb:GBAA_5601(locus name)|uniprotkb:maP3(gene name)|psi-mi:maP3(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:map(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834061|imex:IM-13779-3833	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004557.1|refseq:NP_001269559.1|ensembl:ENSG00000170525.21(gene)|ensembl:ENST00000379775.9(transcript)|go:""GO:0003873""(6-phosphofructo-2-kinase activity)|go:""GO:0004331""(fructose-2,6-bisphosphate 2-phosphatase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006000""(fructose metabolic process)|go:""GO:0006003""(fructose 2,6-bisphosphate metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0010001""(glial cell differentiation)|go:""GO:0061744""(motor behavior)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|mint:Q16875|rcsb pdb:2AXN|rcsb pdb:2DWO|rcsb pdb:2DWP|rcsb pdb:2I1V|rcsb pdb:3QPU|rcsb pdb:3QPV|rcsb pdb:3QPW|rcsb pdb:4D4J|rcsb pdb:4D4K|rcsb pdb:4D4L|rcsb pdb:4D4M|rcsb pdb:4MA4|rcsb pdb:5AJV|rcsb pdb:5AJW|rcsb pdb:5AJX|rcsb pdb:5AJY|rcsb pdb:5AJZ|rcsb pdb:5AK0|rcsb pdb:6ETJ|rcsb pdb:6HVH|rcsb pdb:6HVI|rcsb pdb:6HVJ|rcsb pdb:6IBX|rcsb pdb:6IBY|rcsb pdb:6IBZ|rcsb pdb:6IC0|reactome:R-HSA-9634600|refseq:NP_001300992.1|dip:DIP-33964N|panther:PTHR10606(orthology-group)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|refseq:WP_002096176.1|go:""GO:0004239""(initiator methionyl aminopeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR036005"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:BPxZYy35rU3GFHZ0+i9FpfTQh9s9606	rogid:OjiTf1RBDabUwoE43aSygJwUemc1392	intact-crc:21771BBAF41B50E3|rigid:/QIpFhBSTeVrc098FCk4qjVtiZ4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81LQ9	uniprotkb:Q9UHL3	intact:EBI-2817908|uniprotkb:Q6KMF4|uniprotkb:E9RE75	intact:EBI-2834075|ensembl:ENSP00000353887.6|ensembl:ENSP00000411506.3|ensembl:ENSP00000422174.1|ensembl:ENSP00000513111.1|ensembl:ENSP00000513114.1|ensembl:ENSP00000513116.1|ensembl:ENSP00000513117.1|ensembl:ENSP00000513118.1|ensembl:ENSP00000513119.1|ensembl:ENSP00000513120.1|uniprotkb:O94852|uniprotkb:A8K0F3	psi-mi:q81lq9_bacan(display_long)|uniprotkb:comEA(gene name)|psi-mi:comEA(display_short)|uniprotkb:GBAA_4553(locus name)	psi-mi:f153a_human(display_long)|uniprotkb:FAM153A(gene name)|psi-mi:FAM153A(display_short)|uniprotkb:KIAA0752(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834081|imex:IM-13779-3836	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004509(Competence protein ComEA, helix-hairpin-helix region)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR019554|go:""GO:0003677""(DNA binding)|go:""GO:0006281""(DNA repair)|go:""GO:0015627""(type II protein secretion system complex)|go:""GO:0015628""(protein secretion by the type II secretion system)|go:""GO:0016020""(membrane)|interpro:IPR051675"	ensembl:ENSG00000170074.21(gene)|ensembl:ENST00000360669.11(transcript)|ensembl:ENST00000440605.7(transcript)|ensembl:ENST00000510276.5(transcript)|ensembl:ENST00000697105.1(transcript)|ensembl:ENST00000697109.1(transcript)|ensembl:ENST00000697112.1(transcript)|ensembl:ENST00000697113.1(transcript)|ensembl:ENST00000697115.1(transcript)|ensembl:ENST00000697116.2(transcript)|ensembl:ENST00000697117.1(transcript)|interpro:IPR023249|refseq:XP_011532823.1|refseq:XP_011532824.1|refseq:XP_011532825.1|refseq:NP_775934.3|refseq:XP_006714911.1|refseq:XP_006714912.1|refseq:XP_016864855.1|refseq:XP_016864856.1|refseq:XP_016864857.1|refseq:XP_016864858.1|refseq:XP_016864859.1|refseq:XP_016864860.1|panther:PTHR40712(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iEvG41gaFu5NjfUyZipFRqUjSKs1392	rogid:r21Qmhx2BeEAkf7HmKbPHDmnUvk9606	intact-crc:70F9F9A10A924332|rigid:ne3PEC1gCHSQVllqe+d8y7MFoaM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q16875	uniprotkb:A0A6L7H5N1	intact:EBI-764464|uniprotkb:Q5VX18|uniprotkb:O43622|uniprotkb:O75902|intact:EBI-2834088|uniprotkb:Q5VX19|uniprotkb:B7Z955|ensembl:ENSP00000369100.4|uniprotkb:Q5VX15	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:f263_human(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme(gene name synonym)|uniprotkb:iPFK-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-56(gene name synonym)|uniprotkb:PFKFB3(gene name)|psi-mi:PFKFB3(display_short)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834068|imex:IM-13779-3835	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004557.1|refseq:NP_001269559.1|ensembl:ENSG00000170525.21(gene)|ensembl:ENST00000379775.9(transcript)|go:""GO:0003873""(6-phosphofructo-2-kinase activity)|go:""GO:0004331""(fructose-2,6-bisphosphate 2-phosphatase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006000""(fructose metabolic process)|go:""GO:0006003""(fructose 2,6-bisphosphate metabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0006915""(apoptotic process)|go:""GO:0010001""(glial cell differentiation)|go:""GO:0061744""(motor behavior)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|mint:Q16875|rcsb pdb:2AXN|rcsb pdb:2DWO|rcsb pdb:2DWP|rcsb pdb:2I1V|rcsb pdb:3QPU|rcsb pdb:3QPV|rcsb pdb:3QPW|rcsb pdb:4D4J|rcsb pdb:4D4K|rcsb pdb:4D4L|rcsb pdb:4D4M|rcsb pdb:4MA4|rcsb pdb:5AJV|rcsb pdb:5AJW|rcsb pdb:5AJX|rcsb pdb:5AJY|rcsb pdb:5AJZ|rcsb pdb:5AK0|rcsb pdb:6ETJ|rcsb pdb:6HVH|rcsb pdb:6HVI|rcsb pdb:6HVJ|rcsb pdb:6IBX|rcsb pdb:6IBY|rcsb pdb:6IBZ|rcsb pdb:6IC0|reactome:R-HSA-9634600|refseq:NP_001300992.1|dip:DIP-33964N|panther:PTHR10606(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:BPxZYy35rU3GFHZ0+i9FpfTQh9s9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:13BA2A7E72E12DC2|rigid:2cteOSeDgNYzZM2pNZrb8Sag+3c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IWF6	uniprotkb:A0A6L8PU82	intact:EBI-2834112|ensembl:ENSP00000311401.5|uniprotkb:Q7Z5T4|uniprotkb:Q8TEG8|uniprotkb:Q8N235	intact:EBI-2816012|uniprotkb:Q6KWN0|uniprotkb:Q6I2V4|uniprotkb:E9R9A7|uniprotkb:E9R9A8|uniprotkb:Q81UM4|uniprotkb:A0A0F7RMU4	psi-mi:den6a_human(display_long)|uniprotkb:DENND6A(gene name)|psi-mi:DENND6A(display_short)|uniprotkb:DENN domain-containing protein 6A(gene name synonym)|uniprotkb:FAM116A(gene name synonym)	psi-mi:a0a6l8pu82_bacan(display_long)|uniprotkb:GBAA_0840(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834109|imex:IM-13779-3839	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000174839.13(gene)|ensembl:ENST00000311128.10(transcript)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0055037""(recycling endosome)|go:""GO:2000049""(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR018307|interpro:IPR024224|interpro:IPR037516|reactome:R-HSA-8876198|refseq:NP_689891.1|panther:PTHR13677(orthology-group)"	"interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_000508221.1|interpro:IPR036259"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qEZSBxucL3RjkUCWtCqPQ18jiT09606	rogid:WHUE46U4VqTCqd7VDKz0k40UhNg1392	intact-crc:06480EB65BFB45FA|rigid:NLOmETnP/A9/+pCuxqgB0PkeTMQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81ND5	uniprotkb:Q9NZB2	intact:EBI-2828375|uniprotkb:Q6KQP1|uniprotkb:Q6HWJ4	intact:EBI-1171960|uniprotkb:A6NGU0|uniprotkb:O60649|uniprotkb:Q14688|uniprotkb:Q4VXF4|uniprotkb:Q4VXF5|uniprotkb:Q4VXG2|uniprotkb:Q96I21|uniprotkb:Q9NZB1|uniprotkb:C4AMC6|uniprotkb:Q86V69|intact:EBI-2560129|ensembl:ENSP00000277165.5	psi-mi:luta2_bacan(display_long)|uniprotkb:lutA2(gene name)|psi-mi:lutA2(display_short)|uniprotkb:BA_3270(locus name)|uniprotkb:GBAA_3270(locus name)|uniprotkb:BAS3037(locus name)	psi-mi:f120a_human(display_long)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:Oxidative stress-associated SRC activator(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834102|imex:IM-13779-3837	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004017(Cysteine-rich region, CCG)|interpro:IPR022822|refseq:WP_000868791.1|go:""GO:0005829""(cytosol)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0016491""(oxidoreductase activity)|refseq:NP_845568.1|refseq:YP_029294.1"	"refseq:NP_055427.2|refseq:XP_011516714.1|refseq:NP_001273651.1|refseq:NP_001273652.1|refseq:NP_001273653.1|panther:PTHR15976(orthology-group)|ensembl:ENSG00000048828.18(gene)|ensembl:ENST00000277165.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q9NZB2"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JfKQ30AhvD8d+K3njLh4CIeiNs41392	rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606	intact-crc:EC394DB44624FFE2|rigid:W7ZJYy07AKmQ5fFIfqsnKOVjMW0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HKA9	uniprotkb:Q9H1Q7	intact:EBI-2834123|uniprotkb:Q6KRC5|uniprotkb:Q6HXA3|uniprotkb:E9RC28|uniprotkb:E9RC29|uniprotkb:Q81P31	intact:EBI-748452|uniprotkb:Q5JUA5|uniprotkb:Q5JUA6|uniprotkb:Q6PK19|uniprotkb:Q86WF5|uniprotkb:Q96CG7|uniprotkb:Q9H1Q6|uniprotkb:Q9H6D1|ensembl:ENSP00000353868.2	psi-mi:a0a6l7hka9_bacan(display_long)|uniprotkb:GBAA_2988(locus name)	psi-mi:ped1a_human(display_long)|uniprotkb:PCED1A(gene name)|psi-mi:PCED1A(display_short)|uniprotkb:C20orf81(gene name synonym)|uniprotkb:FAM113A(gene name synonym)|uniprotkb:Protein FAM113A(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-23(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834128|imex:IM-13779-3840	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|refseq:WP_000769373.1|interpro:IPR036259"	refseq:NP_073597.2|refseq:NP_001258097.1|ensembl:ENSG00000132635.17(gene)|ensembl:ENST00000360652.7(transcript)|mint:Q9H1Q7|refseq:XP_005260861.1|refseq:XP_005260862.1|panther:PTHR14469(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8fVUxD1RJ/37K5Ty5t32bHDAbm01392	rogid:L1RRthUFVoaARhQE6LnQV1QLqLk9606	intact-crc:49CD8C2141BD7614|rigid:qyAhkSG6MIhNe1R3ljHpc9irtV8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50502	uniprotkb:A0A6L8PS06	intact:EBI-357285|uniprotkb:O14999|uniprotkb:Q2TU77|ensembl:ENSP00000216218.3	intact:EBI-2822025|uniprotkb:Q6KU39|uniprotkb:Q6I061|uniprotkb:E9QZJ9|uniprotkb:E9QZK0|uniprotkb:Q81RY4|uniprotkb:A0A0F7RKF8	psi-mi:f10a1_human(display_long)|uniprotkb:ST13(gene name)|psi-mi:ST13(display_short)|uniprotkb:HIP(gene name synonym)|uniprotkb:SNC6(gene name synonym)|uniprotkb:AAG2(gene name synonym)|uniprotkb:Aging-associated protein 2(gene name synonym)|uniprotkb:FAM10A1(gene name synonym)|uniprotkb:Suppression of tumorigenicity 13 protein(gene name synonym)|uniprotkb:Putative tumor suppressor ST13(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:Progesterone receptor-associated p48 protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-33(gene name synonym)	psi-mi:a0a6l8ps06_bacan(display_long)|uniprotkb:GBAA_1901(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834135|imex:IM-13779-3838	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003923.2|ensembl:ENSG00000100380.15(gene)|ensembl:ENST00000216218.8(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0009617""(response to bacterium)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0051085""(chaperone cofactor-dependent protein refolding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|mint:P50502|reactome:R-HSA-3371453|panther:PTHR45883(orthology-group)"	"interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|interpro:IPR029149|rcsb pdb:3IG4|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|refseq:WP_000836817.1|interpro:IPR036005"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yqG5t4Kuj7ZzfNwlJzGZYscKiM89606	rogid:awGBqFHW4XysI2ymSlWekBPiTPM1392	intact-crc:DF3DCECB57C2B69E|rigid:QFCygDLEEcZMKVYXnrGBb5xzRBc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81JX0	uniprotkb:Q9UPT5	intact:EBI-2821962|uniprotkb:Q6HQH0|uniprotkb:Q6KJU4	intact:EBI-720048|uniprotkb:Q96FF0|uniprotkb:Q9H8C3|uniprotkb:Q9H9X3|uniprotkb:Q9HA32|uniprotkb:Q8ND93|uniprotkb:Q8WV91|uniprotkb:B5MC69|uniprotkb:B8XXP2|ensembl:ENSP00000334100.6	psi-mi:kith_bacan(display_long)|uniprotkb:tdk(gene name)|psi-mi:tdk(display_short)|uniprotkb:BA_5573(locus name)|uniprotkb:GBAA_5573(locus name)|uniprotkb:BAS5179(locus name)	psi-mi:exoc7_human(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834156|imex:IM-13779-3844	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001267(Thymidine kinase)|interpro:IPR020633|rcsb pdb:2J9R|interpro:IPR027417|go:""GO:0004797""(thymidine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0046104""(thymidine metabolic process)|go:""GO:0071897""(DNA biosynthetic process)|refseq:WP_000280866.1|refseq:NP_847730.1|refseq:YP_031418.1"	"refseq:NP_001013861.1|refseq:NP_001138769.1|refseq:NP_001138770.1|refseq:NP_001138771.1|refseq:NP_056034.2|refseq:NP_001269242.1|ensembl:ENSG00000182473.22(gene)|ensembl:ENST00000335146.11(transcript)|go:""GO:0000145""(exocyst)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005546""(phosphatidylinositol-4,5-bisphosphate binding)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006887""(exocytosis)|go:""GO:0006904""(vesicle docking involved in exocytosis)|go:""GO:0016020""(membrane)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030496""(midbody)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032584""(growth cone membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0090148""(membrane fission)|go:""GO:0090522""(vesicle tethering involved in exocytosis)|go:""GO:0090543""(Flemming body)|go:""GO:1903438""(positive regulation of mitotic cytokinetic process)|go:""GO:2000535""(regulation of entry of bacterium into host cell)|interpro:IPR004140(Exo70 exocyst complex subunit)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR046364|mint:Q9UPT5|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|dip:DIP-37604N|panther:PTHR12542(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:fC2DrvjGW7q89ZmsAOf5lt7m8NY1392	rogid:f/uwscxIcAuG96QZzNMQtrzTmeU9606	intact-crc:DE4D0B9C893ADF39|rigid:7fDrHVI3jK21tTtsy3IYfuLtyeg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01844	uniprotkb:A0A6L7HA16	intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|uniprotkb:B0QYK1|uniprotkb:Q96MN4|ensembl:ENSP00000381031.2|intact:EBI-28987207|intact:EBI-10985407	intact:EBI-2814138|uniprotkb:Q6HQ53|uniprotkb:Q6F078|uniprotkb:E9RDY5|uniprotkb:E9RDY6|uniprotkb:Q81JL0|uniprotkb:A0A0F7R8Z5	psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym)	psi-mi:a0a6l7ha16_bacan(display_long)|uniprotkb:GBAA_5694(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834175|imex:IM-13779-3845	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:209916""|efo:""Orphanet:319""|efo:""Orphanet:370334""|efo:""Orphanet:83469""|efo:""Orphanet:97338""|ensembl:ENSG00000182944.18(gene)|ensembl:ENST00000397938.7(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|refseq:NP_001156757.1|refseq:NP_001156758.1|refseq:NP_001156759.1|refseq:NP_005234.1|refseq:NP_053733.2|dip:DIP-34449N|panther:PTHR23238(orthology-group)"	"interpro:IPR000060(BCCT transporter)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:WP_001242469.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606	rogid:/tOiU2i3Pj5531YNTX3x8RYSwk01392	intact-crc:D5F99A0BA8F2CA53|rigid:mv9xxLNus1qHyHMowuen3NoBRCE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PRU8	uniprotkb:Q9Y3B2	intact:EBI-2815615|uniprotkb:Q6KY09|uniprotkb:Q6I4A6|uniprotkb:E9QTP8|uniprotkb:E9QTP9|uniprotkb:Q81ZF9|uniprotkb:A0A1Q4LXL1	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939.3	psi-mi:a0a6l8pru8_bacan(display_long)|uniprotkb:GBAA_0308(locus name)	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834149|imex:IM-13779-3842	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002781(Protein of unknown function DUF81)|go:""GO:0005886""(plasma membrane)|interpro:IPR052017|refseq:WP_000343964.1"	"refseq:NP_057130.1|ensembl:ENSG00000171311.13(gene)|ensembl:ENST00000370902.8(transcript)|go:""GO:0000176""(""nuclear exosome (RNase complex)"")|go:""GO:0000177""(""cytoplasmic exosome (RNase complex)"")|go:""GO:0000178""(""exosome (RNase complex)"")|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006364""(rRNA processing)|go:""GO:0006396""(RNA processing)|go:""GO:0006401""(RNA catabolic process)|go:""GO:0101019""(""nucleolar exosome (RNase complex)"")|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|rcsb pdb:9G8M|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|dip:DIP-31261N|panther:PTHR12686(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:UbH2vThOpoXHd754F8yAIqAgxBg1392	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	intact-crc:8940A79D60CB75D0|rigid:9hPLRjlyMjEf/pcBXvMEV1ujOAk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NQT5	uniprotkb:A0A6L8NW40	intact:EBI-371866|ensembl:ENSP00000323046.4|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|uniprotkb:A8K0K6	intact:EBI-2817882|uniprotkb:Q6HVQ2|uniprotkb:Q6KPW9|uniprotkb:E9QZA0|uniprotkb:E9QZA1|uniprotkb:Q81YF9	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:a0a6l8nw40_bacan(display_long)|uniprotkb:GBAA_3590(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834142|imex:IM-13779-3843	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000107371.14(gene)|ensembl:ENST00000327304.10(transcript)|go:""GO:0000175""(3'-5'-RNA exonuclease activity)|go:""GO:0000176""(""nuclear exosome (RNase complex)"")|go:""GO:0000177""(""cytoplasmic exosome (RNase complex)"")|go:""GO:0000178""(""exosome (RNase complex)"")|go:""GO:0000467""(""exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0000791""(euchromatin)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006364""(rRNA processing)|go:""GO:0006396""(RNA processing)|go:""GO:0006401""(RNA catabolic process)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0034475""(U4 snRNA 3'-end processing)|go:""GO:0045006""(DNA deamination)|go:""GO:0045190""(isotype switching)|go:""GO:0045830""(positive regulation of isotype switching)|go:""GO:0071034""(CUT catabolic process)|go:""GO:0071035""(nuclear polyadenylation-dependent rRNA catabolic process)|go:""GO:0071038""(TRAMP-dependent tRNA surveillance pathway)|go:""GO:0071051""(""poly(A)-dependent snoRNA 3'-end processing"")|go:""GO:0101019""(""nucleolar exosome (RNase complex)"")|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|interpro:IPR048541|interpro:IPR049469|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|rcsb pdb:9G8M|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001002269.1|refseq:NP_057126.2|efo:""Orphanet:2254""|dip:DIP-29847N|panther:PTHR21321(orthology-group)"	interpro:IPR025006|interpro:IPR025012|refseq:WP_000345027.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	rogid:GXHZ84a8o7jD1cpeglUTg3KeKQo1392	intact-crc:1580C8926D6701C9|rigid:PXwtUQq7dhktKM0ZnzFSofZZ0hk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01844	uniprotkb:A0A3P1UGW8	intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|uniprotkb:B0QYK1|uniprotkb:Q96MN4|ensembl:ENSP00000381031.2|intact:EBI-28987207|intact:EBI-10985407	intact:EBI-2834166|uniprotkb:Q6KM83|uniprotkb:Q6HSZ4|uniprotkb:E9QWQ8|uniprotkb:E9QWQ9|uniprotkb:Q81LI8|uniprotkb:A0A1J9WUX0|uniprotkb:A0A2A8LH07	psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym)	psi-mi:a0a3p1ugw8_bacan(display_long)|uniprotkb:GBAA_4630(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834163|imex:IM-13779-3841	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:209916""|efo:""Orphanet:319""|efo:""Orphanet:370334""|efo:""Orphanet:83469""|efo:""Orphanet:97338""|ensembl:ENSG00000182944.18(gene)|ensembl:ENST00000397938.7(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|refseq:NP_001156757.1|refseq:NP_001156758.1|refseq:NP_001156759.1|refseq:NP_005234.1|refseq:NP_053733.2|dip:DIP-34449N|panther:PTHR23238(orthology-group)"	"go:""GO:0008641""(ubiquitin-like modifier activating enzyme activity)|go:""GO:0061503""(tRNA threonylcarbamoyladenosine dehydratase)|go:""GO:0061504""(cyclic threonylcarbamoyladenosine biosynthetic process)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|refseq:WP_000903177.1|interpro:IPR035985|interpro:IPR045886"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606	rogid:k0AUWWtdirTZNtMM/0avZkqIlGM1392	intact-crc:65BE677309F87F05|rigid:dKgpnQeEKnorpPP4IfaWWvhpfKM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81L10	uniprotkb:Q01844	intact:EBI-2810713|uniprotkb:Q6KLR0|uniprotkb:Q6HSG5	intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|uniprotkb:B0QYK1|uniprotkb:Q96MN4|ensembl:ENSP00000381031.2|intact:EBI-28987207|intact:EBI-10985407	psi-mi:nrdr_bacan(display_long)|uniprotkb:nrdR(gene name)|psi-mi:nrdR(display_short)|uniprotkb:BA_4824(locus name)|uniprotkb:GBAA_4824(locus name)|uniprotkb:BAS4476(locus name)	psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834182|imex:IM-13779-3848	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005144(ATP-cone)|interpro:IPR003796(Ribonucleotide reductase regulator NrdR-like)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR055173|refseq:WP_001203687.1|refseq:NP_847027.2|refseq:YP_030723.1"	"efo:""Orphanet:209916""|efo:""Orphanet:319""|efo:""Orphanet:370334""|efo:""Orphanet:83469""|efo:""Orphanet:97338""|ensembl:ENSG00000182944.18(gene)|ensembl:ENST00000397938.7(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|refseq:NP_001156757.1|refseq:NP_001156758.1|refseq:NP_001156759.1|refseq:NP_005234.1|refseq:NP_053733.2|dip:DIP-34449N|panther:PTHR23238(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:kG3YzLvKveoCeDX0WPFsMLvS+a01392	rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606	intact-crc:6BE871CCA05A8D9D|rigid:R4SV9PAtYgHCpl9bvMPk0oUOj6o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81P27	uniprotkb:P15036	intact:EBI-2814639|uniprotkb:Q6KRC1|uniprotkb:Q6HX99	intact:EBI-1646991|uniprotkb:D3DSH6|uniprotkb:A6NM68|uniprotkb:Q53Y89|ensembl:ENSP00000353344.3|ensembl:ENSP00000354194.3|ensembl:ENSP00000499226.1|ensembl:ENSP00000499315.1|ensembl:ENSP00000499775.1	psi-mi:proa_bacan(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:BA_2992(locus name)|uniprotkb:GBAA_2992(locus name)|uniprotkb:BAS2781(locus name)	psi-mi:ets2_human(display_long)|uniprotkb:ETS2(gene name)|psi-mi:ETS2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834203|imex:IM-13779-3850	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|go:""GO:0004350""(glutamate-5-semialdehyde dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0050661""(NADP binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:NP_845325.1|refseq:YP_029039.1|refseq:WP_001006638.1"	"refseq:NP_005230.1|refseq:XP_016883779.1|refseq:XP_005260992.1|dip:DIP-40452N|ensembl:ENSG00000157557.13(gene)|ensembl:ENST00000360214.8(transcript)|ensembl:ENST00000360938.8(transcript)|ensembl:ENST00000653642.1(transcript)|ensembl:ENST00000662305.1(transcript)|ensembl:ENST00000666778.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001501""(skeletal system development)|go:""GO:0001712""(ectodermal cell fate commitment)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007498""(mesoderm development)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0035259""(nuclear glucocorticoid receptor binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0090009""(primitive streak formation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR027276|interpro:IPR036388|interpro:IPR036390|interpro:IPR045688|interpro:IPR046328|mint:P15036|rcsb pdb:4BQA|rcsb pdb:4MHV|reactome:R-HSA-2559585|panther:PTHR11849(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2iR76/3cLX7gyVDMLNG2KEyBoMY1392	rogid:mHFB3G4Y52dZ3dUM2zbx+vamz9c9606	intact-crc:50E9AED51596B64A|rigid:mp3+fozhHqvycic9lnl582kii7c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95571	uniprotkb:Q81S26	intact:EBI-715318|uniprotkb:Q96HR0|uniprotkb:Q9H001|ensembl:ENSP00000292147.1	intact:EBI-2811143|uniprotkb:Q6KU79|uniprotkb:Q6I0A5	psi-mi:ethe1_human(display_long)|uniprotkb:Ethylmalonic encephalopathy protein 1(gene name synonym)|uniprotkb:Hepatoma subtracted clone one protein(gene name synonym)|uniprotkb:ETHE1(gene name)|psi-mi:ETHE1(display_short)|uniprotkb:HSCO(gene name synonym)|uniprotkb:Sulfur dioxygenase ETHE1(gene name synonym)	psi-mi:ilvd_bacan(display_long)|uniprotkb:ilvD(gene name)|psi-mi:ilvD(display_short)|uniprotkb:BA_1853(locus name)|uniprotkb:GBAA_1853(locus name)|uniprotkb:BAS1717(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834210|imex:IM-13779-3846	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:51188""|ensembl:ENSG00000105755.8(gene)|ensembl:ENST00000292147.7(transcript)|go:""GO:0005506""(iron ion binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006749""(glutathione metabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0050313""(sulfur dioxygenase activity)|go:""GO:0070813""(hydrogen sulfide metabolic process)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR036866|interpro:IPR044528|interpro:IPR051682|mint:O95571|rcsb pdb:4CHL|reactome:R-HSA-1614517|refseq:NP_001307796.1|refseq:NP_001307797.1|refseq:NP_001307798.1|refseq:NP_055112.2|refseq:XP_005258744.1|panther:PTHR43084(orthology-group)"	"interpro:IPR004404(Dihydroxy-acid dehydratase)|interpro:IPR000581(Dihydroxy-acid and 6-phosphogluconate dehydratase)|interpro:IPR020558|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004160""(dihydroxy-acid dehydratase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|refseq:WP_001255799.1|interpro:IPR037237|interpro:IPR042096|refseq:NP_844270.1|refseq:YP_027982.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:a7+fXdb2iEny5lCHBrJu+zRvyLs9606	rogid:2rwY7biS4Is4mpOU8lcawsTzqSU1392	intact-crc:6454B9D462962869|rigid:l3f0yJ9xyIN6gQKC+G/KxcwwI4c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P41212	uniprotkb:A0A6L8PLI9	intact:EBI-1372759|uniprotkb:A3QVP6|uniprotkb:Q9UMF6|uniprotkb:Q9UMF7|uniprotkb:Q9UMG0|uniprotkb:A8K076|ensembl:ENSP00000379658.3	intact:EBI-2816451|uniprotkb:Q6KM01|uniprotkb:Q6HSR0|uniprotkb:E9R8G8|uniprotkb:E9R8G9|uniprotkb:Q81LA6|uniprotkb:A0A2B6C7C6	psi-mi:etv6_human(display_long)|uniprotkb:ETS translocation variant 6(gene name synonym)|uniprotkb:ETS-related protein Tel1(gene name synonym)|uniprotkb:ETV6(gene name)|psi-mi:ETV6(display_short)|uniprotkb:TEL(gene name synonym)|uniprotkb:TEL1(gene name synonym)	psi-mi:a0a6l8pli9_bacan(display_long)|uniprotkb:GBAA_4720(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834196|imex:IM-13779-3847	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:146""|efo:""Orphanet:2030""|efo:""Orphanet:2665""|efo:""Orphanet:314950""|efo:""Orphanet:585929""|efo:""Orphanet:98823""|efo:""Orphanet:168629""|ensembl:ENSG00000139083.11(gene)|ensembl:ENST00000396373.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007296""(vitellogenesis)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0022008""(neurogenesis)|go:""GO:0071425""(hematopoietic stem cell proliferation)|go:""GO:0097152""(mesenchymal cell apoptotic process)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|interpro:IPR046328|mint:P41212|rcsb pdb:1JI7|rcsb pdb:1LKY|rcsb pdb:2DAO|rcsb pdb:2QAR|rcsb pdb:2QB0|rcsb pdb:2QB1|rcsb pdb:5L0P|rcsb pdb:7JU2|rcsb pdb:7N1O|rcsb pdb:7N2B|rcsb pdb:7T8J|rcsb pdb:7TDY|rcsb pdb:7TW7|rcsb pdb:7TW8|rcsb pdb:7TW9|rcsb pdb:7U4W|rcsb pdb:7U4Z|rcsb pdb:8BWU|rcsb pdb:8E1F|rcsb pdb:8FRJ|rcsb pdb:8FRK|rcsb pdb:8FT6|rcsb pdb:8FT8|rcsb pdb:8FZ3|rcsb pdb:8FZU|rcsb pdb:8FZV|rcsb pdb:8THA|rcsb pdb:9DAM|rcsb pdb:9DB5|rcsb pdb:9DP8|rcsb pdb:9DVG|rcsb pdb:9FEH|reactome:R-HSA-9673768|reactome:R-HSA-9703465|refseq:NP_001978.1|dip:DIP-17028N|panther:PTHR11849(orthology-group)"	"interpro:IPR002818(ThiJ/PfpI)|interpro:IPR029062|go:""GO:0005737""(cytoplasm)|go:""GO:0019172""(glyoxalase III activity)|go:""GO:0019243""(methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione)|interpro:IPR050325|refseq:WP_000728506.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ekItHLbEk2Expb+mR7jHa6dPBo89606	rogid:QaShW4RsgZDqoTdPWReuHiXNRgo1392	intact-crc:CEF736C7C19BB5BA|rigid:Wy19+D0Ew+iBb0CV1wMMYbQDXwM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PE91	uniprotkb:Q01844	intact:EBI-2814541|uniprotkb:Q6KNX1|uniprotkb:Q6HUN8|uniprotkb:E9R2M4|uniprotkb:E9R2M5|uniprotkb:Q81WI9	intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|uniprotkb:B0QYK1|uniprotkb:Q96MN4|ensembl:ENSP00000381031.2|intact:EBI-28987207|intact:EBI-10985407	psi-mi:a0a6l8pe91_bacan(display_long)|uniprotkb:smC(gene name)|psi-mi:smC(display_short)|uniprotkb:GBAA_3986(locus name)|uniprotkb:smc(gene name synonym)	psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834189|imex:IM-13779-3849	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0006260""(DNA replication)|go:""GO:0007059""(chromosome segregation)|go:""GO:0007062""(sister chromatid cohesion)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030261""(chromosome condensation)|refseq:WP_000478985.1|interpro:IPR036277"	"efo:""Orphanet:209916""|efo:""Orphanet:319""|efo:""Orphanet:370334""|efo:""Orphanet:83469""|efo:""Orphanet:97338""|ensembl:ENSG00000182944.18(gene)|ensembl:ENST00000397938.7(transcript)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0042802""(identical protein binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|refseq:NP_001156757.1|refseq:NP_001156758.1|refseq:NP_001156759.1|refseq:NP_005234.1|refseq:NP_053733.2|dip:DIP-34449N|panther:PTHR23238(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:InHdr6Cf4ksd4cY+XUmSGD/hNyE1392	rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606	intact-crc:CED5A9690FD8A962|rigid:9UVNxiJvgpV2sCG+NtrAQBav0u4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8P2X1	uniprotkb:Q96J88	intact:EBI-2811664|uniprotkb:Q6HWH8|uniprotkb:Q6KQM9|uniprotkb:E9QRE5|uniprotkb:E9QRE6|uniprotkb:Q81NC2|uniprotkb:A0A0F7R9W0	intact:EBI-2834237|ensembl:ENSP00000381746.3|uniprotkb:Q8NDQ7|uniprotkb:Q8IVC7	psi-mi:a0a6l8p2x1_bacan(display_long)|uniprotkb:GBAA_3288(locus name)	psi-mi:esip1_human(display_long)|uniprotkb:EPSTI1(gene name)|psi-mi:EPSTI1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834243|imex:IM-13779-3853	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR043502|interpro:IPR017961|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR043128|interpro:IPR024728|interpro:IPR050116|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0009432""(SOS response)|go:""GO:0042276""(error-prone translesion synthesis)|refseq:WP_000272549.1|interpro:IPR036775"	ensembl:ENSG00000133106.15(gene)|ensembl:ENST00000398762.7(transcript)|interpro:IPR026185|mint:Q96J88|reactome:R-HSA-9696273|refseq:NP_001002264.1|refseq:NP_150280.1|refseq:NP_001318157.1|refseq:NP_001317472.1|panther:PTHR22529(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fUIT+VEfXS3bjWD3plCkaA/yspE1392	rogid:Q2zfhjkceeL5sFJ28KKzLA/bpPY9606	intact-crc:339DEDBE3092268C|rigid:OS1nGxmrRC9aRMZHgIELs1WFgvc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BSJ8	uniprotkb:A0A6L7HQN9	intact:EBI-355956|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548|ensembl:ENSP00000377612.5|intact:EBI-21360363	intact:EBI-2817047|uniprotkb:Q6I3I6|uniprotkb:Q6KX99|uniprotkb:E9QRL6|uniprotkb:E9QRL7|uniprotkb:A0A2P0H9V8|uniprotkb:Q81V99	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:a0a6l7hqn9_bacan(display_long)|uniprotkb:GBAA_0599(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834217|imex:IM-13779-3851	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001171725.1|refseq:NP_056107.1|ensembl:ENSG00000139641.13(gene)|ensembl:ENST00000394048.10(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0008429""(phosphatidylethanolamine binding)|go:""GO:0016020""(membrane)|go:""GO:0031210""(phosphatidylcholine binding)|go:""GO:0035091""(phosphatidylinositol binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:0120014""(phospholipid transfer activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|interpro:IPR051634|mint:Q9BSJ8|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9845576|dip:DIP-57197N|panther:PTHR45761(orthology-group)"	"interpro:IPR023612|interpro:IPR001570(Peptidase M4, thermolysin C-terminal)|interpro:IPR013856(Peptidase M4, thermolysin)|interpro:IPR011096(Propeptide, peptidase M4 and M36)|interpro:IPR025711|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|interpro:IPR050728|refseq:WP_000730364.1|interpro:IPR027268"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rogid:qCDtY8zV2Hhcv5Mw/76uLDHVRKE1392	intact-crc:0D9DC8CA9C45D83E|rigid:eu50uWZK6kzEpuRje84mAfNXGZU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H5N1	uniprotkb:Q6UWW8	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	intact:EBI-2834224|ensembl:ENSP00000304782.4|uniprotkb:Q7Z6J1|uniprotkb:B2Z3W9|uniprotkb:F5H242|uniprotkb:Q9H6X7	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	psi-mi:est3_human(display_long)|uniprotkb:CES3(gene name)|psi-mi:CES3(display_short)|uniprotkb:Liver carboxylesterase 31 homolog(gene name synonym)|uniprotkb:UNQ869/PRO1887(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834230|imex:IM-13779-3852	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"ensembl:ENSG00000172828.13(gene)|ensembl:ENST00000303334.9(transcript)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005829""(cytosol)|go:""GO:0006805""(xenobiotic metabolic process)|go:""GO:0034383""(low-density lipoprotein particle clearance)|go:""GO:0052689""(carboxylic ester hydrolase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106435""(carboxylesterase activity)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019826|interpro:IPR029058|interpro:IPR050309|reactome:R-HSA-211945|reactome:R-HSA-8964038|refseq:NP_001172105.1|refseq:NP_001172106.1|refseq:NP_079198.2|panther:PTHR11559(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	rogid:cCXBzgQFhG7UyYDK8q00I/TW9Sw9606	intact-crc:6A7516E3AC6DA554|rigid:yLIKhyXqB/kpFZ/EHMDrihUL9TQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81X77	uniprotkb:P0DPI2	intact:EBI-2810439|uniprotkb:Q6HR13|uniprotkb:Q6KKD2	intact:EBI-61079469|ensembl:ENSP00000291577.6|uniprotkb:A6NFJ6|uniprotkb:A6NJY7|uniprotkb:O00650|uniprotkb:O00660|uniprotkb:O15011|uniprotkb:O15012|uniprotkb:P30042|uniprotkb:P55346|uniprotkb:P78474|uniprotkb:Q92505|uniprotkb:Q92507	psi-mi:gpmi_bacan(display_long)|uniprotkb:gpmI(gene name)|psi-mi:gpmI(display_short)|uniprotkb:gpmA(gene name synonym)|uniprotkb:BA_5365(locus name)|uniprotkb:GBAA_5365(locus name)|uniprotkb:BAS4986(locus name)	psi-mi:gal3a_human(display_long)|uniprotkb:GATD3(gene name)|psi-mi:GATD3(display_short)|uniprotkb:C21orf33(gene name synonym)|uniprotkb:GATD3A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834285|imex:IM-13779-3855	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR011258(BPG-independent PGAM, N-terminal)|interpro:IPR006124(Metalloenzyme)|interpro:IPR005995(Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent)|rcsb pdb:2IFY|go:""GO:0005829""(cytosol)|go:""GO:0006007""(glucose catabolic process)|go:""GO:0006096""(glycolytic process)|go:""GO:0030145""(manganese ion binding)|go:""GO:0030435""(sporulation resulting in formation of a cellular spore)|go:""GO:0043937""(regulation of sporulation)|go:""GO:0046537""(obsolete 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity)|refseq:WP_001231153.1|interpro:IPR036646|refseq:NP_847539.1|refseq:YP_031225.1"	"ensembl:ENSG00000160221.18(gene)|ensembl:ENST00000291577.11(transcript)|go:""GO:0005739""(mitochondrion)|interpro:IPR029062|refseq:NP_937798.4|refseq:NP_004640.4|panther:PTHR10224(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/21	rogid:pxX2Dycc6/EBhmFHPZ5uVcHE6I41392	rogid:CV66j34bvaZ1sxNMzdW2acrkgZA9606	intact-crc:C876AA3A7EA025E6|rigid:z/FAfQCj8KX0uEfGtbNC0eIKP00	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PZS0	uniprotkb:P0DPI2	intact:EBI-2831915|uniprotkb:Q6KLT8|uniprotkb:Q6HSJ3|uniprotkb:E9QRT9|uniprotkb:E9QRU0|uniprotkb:A0A2P0HJH5|uniprotkb:Q81L39	intact:EBI-61079469|ensembl:ENSP00000291577.6|uniprotkb:A6NFJ6|uniprotkb:A6NJY7|uniprotkb:O00650|uniprotkb:O00660|uniprotkb:O15011|uniprotkb:O15012|uniprotkb:P30042|uniprotkb:P55346|uniprotkb:P78474|uniprotkb:Q92505|uniprotkb:Q92507	psi-mi:a0a6l8pzs0_bacan(display_long)|uniprotkb:GBAA_4795(locus name)	psi-mi:gal3a_human(display_long)|uniprotkb:GATD3(gene name)|psi-mi:GATD3(display_short)|uniprotkb:C21orf33(gene name synonym)|uniprotkb:GATD3A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834250|imex:IM-13779-3854	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029398|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR022311|interpro:IPR047967|refseq:WP_000867530.1|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042578""(phosphoric ester hydrolase activity)|interpro:IPR027421|interpro:IPR037160|interpro:IPR043519|interpro:IPR050243"	"ensembl:ENSG00000160221.18(gene)|ensembl:ENST00000291577.11(transcript)|go:""GO:0005739""(mitochondrion)|interpro:IPR029062|refseq:NP_937798.4|refseq:NP_004640.4|panther:PTHR10224(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/21	rogid:eadaVC645BZc9HjE8igO54X7Ea81392	rogid:CV66j34bvaZ1sxNMzdW2acrkgZA9606	intact-crc:43447C8018E1D5B1|rigid:3UXG3wJZZKgaHjxSFfP6u7Y9kpk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81WR4	uniprotkb:P62508	intact:EBI-2813120|uniprotkb:Q6KP44|uniprotkb:Q6HUW8	intact:EBI-2834260|ensembl:ENSP00000386171.3|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	psi-mi:mutl_bacan(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:BA_3904(locus name)|uniprotkb:GBAA_3904(locus name)|uniprotkb:BAS3617(locus name)	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834257|imex:IM-13779-3856	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020667|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR038973|go:""GO:0005524""(ATP binding)|go:""GO:0006298""(mismatch repair)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030983""(mismatched DNA binding)|go:""GO:0032300""(mismatch repair complex)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|refseq:WP_000516478.1|interpro:IPR036890|interpro:IPR037198|interpro:IPR042120|interpro:IPR042121|refseq:NP_846151.1|refseq:YP_029870.1"	"ensembl:ENSG00000196482.18(gene)|ensembl:ENST00000408911.8(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003707""(nuclear steroid receptor activity)|go:""GO:0004879""(nuclear receptor activity)|go:""GO:0005496""(steroid binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030518""(nuclear receptor-mediated steroid hormone signaling pathway)|go:""GO:0034056""(estrogen response element binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048384""(retinoic acid receptor signaling pathway)|go:""GO:0050682""(AF-2 domain binding)|go:""GO:0120162""(positive regulation of cold-induced thermogenesis)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|interpro:IPR050200|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|rcsb pdb:8B4Q|rcsb pdb:8BJG|rcsb pdb:8BJN|rcsb pdb:8BM5|rcsb pdb:8IFO|reactome:R-HSA-383280|refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:NP_001230443.1|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856120.1|refseq:XP_016856121.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1|panther:PTHR48092(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OVMVMr8TlQnT2VuMnSQlFsmQhbU1392	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	intact-crc:AB3E672A7CA776F8|rigid:lm18Hc11gCRLmiP84rYogUcYksQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P11474	uniprotkb:A0A0F7REH3	intact:EBI-372412|ensembl:ENSP00000000442.6|ensembl:ENSP00000384851.1|uniprotkb:Q14514	intact:EBI-2811064|uniprotkb:Q6KPV8|uniprotkb:E9R093|uniprotkb:Q81YE8	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:a0a0f7reh3_bacan(display_long)|uniprotkb:GBAA_3601(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834278|imex:IM-13779-3857	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000173153.17(gene)|ensembl:ENST00000000442.11(transcript)|ensembl:ENST00000405666.5(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001650""(fibrillar center)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003707""(nuclear steroid receptor activity)|go:""GO:0004879""(nuclear receptor activity)|go:""GO:0005496""(steroid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030518""(nuclear receptor-mediated steroid hormone signaling pathway)|go:""GO:0034056""(estrogen response element binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045171""(intercellular bridge)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|interpro:IPR050200|mint:P11474|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902|refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|panther:PTHR48092(orthology-group)"	refseq:WP_001116379.1|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/01	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rogid:kRV2TrznOHMKW2jOg5FKoFx9L+41392	intact-crc:56ECF9E171B3B570|rigid:wo5hAuACeMlnZ18uivuSsVsyiQs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15197	uniprotkb:A0A6L7HAD6	intact:EBI-714076|uniprotkb:D3DXD3|uniprotkb:A4D2I7|uniprotkb:A8CDT5|uniprotkb:Q2TB23|uniprotkb:Q2TB24	intact:EBI-2812745|uniprotkb:Q6I0C7|uniprotkb:Q6KU98|uniprotkb:E9R9U3|uniprotkb:E9R9U4|uniprotkb:Q81S48|uniprotkb:A0A0F7RJG0	psi-mi:ephb6_human(display_long)|uniprotkb:Tyrosine-protein kinase-defective receptor EPH-6(gene name synonym)|uniprotkb:HEP(gene name synonym)|uniprotkb:EPHB6(gene name)|psi-mi:EPHB6(display_short)	psi-mi:a0a6l7had6_bacan(display_long)|uniprotkb:hflX(gene name)|psi-mi:hflX(display_short)|uniprotkb:GTP-binding protein HflX(gene name synonym)|uniprotkb:GBAA_1828(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834328|imex:IM-13779-3860	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004436.4|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011641(GCC2 and GCC3)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR027936|go:""GO:0005003""(ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007411""(axon guidance)|go:""GO:0030425""(dendrite)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0048013""(ephrin receptor signaling pathway)|rcsb pdb:7K7J|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|refseq:NP_001267724.2|mint:O15197|interpro:IPR036116|interpro:IPR050449|panther:PTHR46877(orthology-group)"	"interpro:IPR016496(GTP-binding protein, HflX)|interpro:IPR006073(GTP1/OBG)|interpro:IPR025121|interpro:IPR027417|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0043022""(ribosome binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR030394|refseq:WP_000391894.1|interpro:IPR032305|interpro:IPR042108"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/Cho3/AfLBjPpycKjnm5BogzGbE9606	rogid:Kmi3AoYo5R9a/xzoJkAFK1EdX2U1392	intact-crc:925DABDBDB91024A|rigid:S0aGpzEcx1tqkNpwuWGlmF8udq8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95925	uniprotkb:A0A6L8PZ36	intact:EBI-2834317|ensembl:ENSP00000361746.4|uniprotkb:A6PVD6|uniprotkb:Q86TP9|uniprotkb:Q9HD30|uniprotkb:Q96SD7	intact:EBI-2821331|uniprotkb:Q6HUX4|uniprotkb:Q6KP50|uniprotkb:E9QRE0|uniprotkb:E9QRE1|uniprotkb:A0A2P0HHZ8|uniprotkb:Q81WS0	psi-mi:eppi_human(display_long)|uniprotkb:EPPIN(gene name)|psi-mi:EPPIN(display_short)|uniprotkb:Cancer/testis antigen 71(gene name synonym)|uniprotkb:Epididymal protease inhibitor(gene name synonym)|uniprotkb:Protease inhibitor WAP7(gene name synonym)|uniprotkb:SPINLW1(gene name synonym)|uniprotkb:Serine protease inhibitor-like with Kunitz and WAP domains 1(gene name synonym)|uniprotkb:WAP four-disulfide core domain protein 7(gene name synonym)|uniprotkb:WAP7(gene name synonym)|uniprotkb:WFDC7(gene name synonym)	psi-mi:a0a6l8pz36_bacan(display_long)|uniprotkb:GBAA_3898(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834314|imex:IM-13779-3858	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000101448.14(gene)|ensembl:ENST00000354280.9(transcript)|go:""GO:0001669""(acrosomal vesicle)|go:""GO:0004867""(serine-type endopeptidase inhibitor activity)|go:""GO:0005615""(extracellular space)|go:""GO:0009986""(cell surface)|go:""GO:0010466""(negative regulation of peptidase activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0090281""(negative regulation of calcium ion import)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:1901318""(negative regulation of flagellated sperm motility)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR008197(Whey acidic protein, 4-disulphide core)|interpro:IPR020901|interpro:IPR036645|interpro:IPR036880|interpro:IPR051388|reactome:R-HSA-6803157|refseq:NP_065131.1|refseq:NP_001185915.1|refseq:NP_001289790.1|panther:PTHR46751(orthology-group)"	"interpro:IPR029055|interpro:IPR029132|go:""GO:0016787""(hydrolase activity)|refseq:WP_000337576.1|interpro:IPR052193"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IuIUs5etxNPYnI9M5juR0sPSKDw9606	rogid:hVn/v6nWOaowYpS+aaAE6tuJYS81392	intact-crc:DBFE7914126B6D32|rigid:LtXz4SzOZu9b52RcWFkRJ5DCOOk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0F7RE19	uniprotkb:Q12929	intact:EBI-2809783|uniprotkb:Q6KPM6|uniprotkb:Q6HVF7|uniprotkb:E9QS28|uniprotkb:E9QS29|uniprotkb:Q81Y62	intact:EBI-375576|uniprotkb:A6NMC3|uniprotkb:Q8N6J0|uniprotkb:B4DX66|uniprotkb:A8K6W2|uniprotkb:A8KA66|ensembl:ENSP00000281172.5|ensembl:ENSP00000441867.1|ensembl:ENSP00000442388.1|ensembl:ENSP00000494689.1|ensembl:ENSP00000494842.1|ensembl:ENSP00000495722.1|ensembl:ENSP00000495824.1|ensembl:ENSP00000495956.1|ensembl:ENSP00000496406.1|ensembl:ENSP00000496516.1	psi-mi:a0a0f7re19_bacan(display_long)|uniprotkb:GBAA_3695(locus name)	psi-mi:eps8_human(display_long)|uniprotkb:EPS8(gene name)|psi-mi:EPS8(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834307|imex:IM-13779-3859	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001119(S-layer homology region)|interpro:IPR051465|go:""GO:0030115""(S-layer)|interpro:IPR032247"	"ensembl:ENSG00000151491.14(gene)|ensembl:ENST00000281172.10(transcript)|ensembl:ENST00000543523.5(transcript)|ensembl:ENST00000543612.5(transcript)|ensembl:ENST00000642278.1(transcript)|ensembl:ENST00000644374.1(transcript)|ensembl:ENST00000645775.1(transcript)|ensembl:ENST00000646828.1(transcript)|ensembl:ENST00000646918.1(transcript)|ensembl:ENST00000647087.1(transcript)|ensembl:ENST00000647224.1(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005938""(cell cortex)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0010458""(exit from mitosis)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0017146""(NMDA selective glutamate receptor complex)|go:""GO:0030426""(growth cone)|go:""GO:0030832""(regulation of actin filament length)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031982""(vesicle)|go:""GO:0032420""(stereocilium)|go:""GO:0032426""(stereocilium tip)|go:""GO:0032587""(ruffle membrane)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0036336""(dendritic cell migration)|go:""GO:0048149""(behavioral response to ethanol)|go:""GO:0051016""(barbed-end actin filament capping)|go:""GO:0051017""(actin filament bundle assembly)|go:""GO:0051764""(actin crosslink formation)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070358""(actin polymerization-dependent cell motility)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:1900029""(positive regulation of ruffle assembly)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033928|interpro:IPR035462|interpro:IPR036028|interpro:IPR039801|interpro:IPR041418|interpro:IPR055093|mint:Q12929|rcsb pdb:2E8M|rcsb pdb:7TZK|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_004438.3|efo:""Orphanet:90636""|dip:DIP-32859N|panther:PTHR12287(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:RZeq/OQN8n8nnEe280+/uO/FFX01392	rogid:ulBgb+4uZ7XrN4bLogRtd9I5AbY9606	intact-crc:90F2481346ED3099|rigid:RAhRL7UaINGibSxzd7dVoKfExSU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HRA4	uniprotkb:Q6P179	intact:EBI-2813473|uniprotkb:Q6HQQ3|uniprotkb:Q6KK24|uniprotkb:E9R8B1|uniprotkb:E9R8B2|uniprotkb:Q81K50|uniprotkb:A0A0F7R5G0	intact:EBI-2834295|ensembl:ENSP00000400376.3|ensembl:ENSP00000421175.2|uniprotkb:Q9HBX2|uniprotkb:Q7Z5K1|uniprotkb:Q8WVJ4|uniprotkb:Q8TD32	psi-mi:a0a6l7hra4_bacan(display_long)|uniprotkb:GBAA_5487(locus name)	psi-mi:erap2_human(display_long)|uniprotkb:ERAP2(gene name)|psi-mi:ERAP2(display_short)|uniprotkb:LRAP(gene name synonym)|uniprotkb:Leukocyte-derived arginine aminopeptidase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834292|imex:IM-13779-3861	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022138|interpro:IPR000330(SNF2-related)|interpro:IPR038718|interpro:IPR027417|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016787""(hydrolase activity)|refseq:WP_000610083.1|interpro:IPR049730"	"ensembl:ENSG00000164308.18(gene)|ensembl:ENST00000437043.8(transcript)|ensembl:ENST00000510373.6(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002474""(antigen processing and presentation of peptide antigen via MHC class I)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016020""(membrane)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0042277""(peptide binding)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|interpro:IPR045357|interpro:IPR050344|rcsb pdb:3SE6|rcsb pdb:4E36|rcsb pdb:4JBS|rcsb pdb:5AB0|rcsb pdb:5AB2|rcsb pdb:5CU5|rcsb pdb:5J6S|rcsb pdb:5K1V|rcsb pdb:6EA4|rcsb pdb:7NSK|rcsb pdb:7NUP|rcsb pdb:7P7P|rcsb pdb:7PFS|rcsb pdb:7SH0|reactome:R-HSA-983170|refseq:NP_001123612.1|refseq:NP_071745.1|refseq:NP_001316158.1|refseq:NP_001316162.1|panther:PTHR11533(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Cs/6ntowxGUivXGkMJr5JhYRMVk1392	rogid:3rB8/Jowwhr6UxmLtp+OLT6OfMM9606	intact-crc:AAF530C9D23AC110|rigid:JABj3mxInWxeDEUUGlPJhSVnzc0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81Y46	uniprotkb:Q9UBC2	intact:EBI-2812495|uniprotkb:Q6KPL0|uniprotkb:Q6HVE1	intact:EBI-2556746|intact:EBI-28972990|uniprotkb:B4DKA3|uniprotkb:A2RRF3|uniprotkb:A5PL29|ensembl:ENSP00000248070.5	psi-mi:hutu_bacan(display_long)|uniprotkb:hutU(gene name)|psi-mi:hutU(display_short)|uniprotkb:Imidazolonepropionate hydrolase(gene name synonym)|uniprotkb:BA_3711(locus name)|uniprotkb:GBAA_3711(locus name)|uniprotkb:BAS3441(locus name)	psi-mi:ep15r_human(display_long)|uniprotkb:EPS15R(gene name synonym)|uniprotkb:Eps15-related protein(gene name synonym)|uniprotkb:EPS15L1(gene name)|psi-mi:EPS15L1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834349|imex:IM-13779-3862	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR035085|interpro:IPR023636|interpro:IPR023637|go:""GO:0005737""(cytoplasm)|go:""GO:0016153""(urocanate hydratase activity)|go:""GO:0019556""(L-histidine catabolic process to glutamate and formamide)|go:""GO:0019557""(L-histidine catabolic process to glutamate and formate)|refseq:WP_000416715.1|interpro:IPR038364|interpro:IPR035401|interpro:IPR035400|interpro:IPR036190|refseq:NP_845974.1|refseq:YP_029697.1"	"ensembl:ENSG00000127527.15(gene)|ensembl:ENST00000248070.10(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006897""(endocytosis)|go:""GO:0016020""(membrane)|go:""GO:0016197""(endosomal transport)|go:""GO:0030132""(clathrin coat of coated pit)|go:""GO:0045296""(cadherin binding)|interpro:IPR000261(""EPS15 homology (EH)"")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|mint:Q9UBC2|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001245303.1|refseq:NP_001245304.1|refseq:NP_001245305.1|refseq:NP_067058.1|efo:""Orphanet:2440""|panther:PTHR11216(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bokqO9GavtjceeT8eQKHFW32guU1392	rogid:6Bsao5czetxRxIiy3O/rZox4U+Y9606	intact-crc:E39008994E014D70|rigid:qxYx9f4TPo/NUK9RRY2RcLUJFes	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H9C3	uniprotkb:Q09472	intact:EBI-2812297|uniprotkb:Q6KK92|uniprotkb:Q6HQX4|uniprotkb:E9R1I9|uniprotkb:E9R1J0|uniprotkb:Q81X37|uniprotkb:A0A1Q4LY85	intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|ensembl:ENSP00000263253.7|ensembl:ENSP00000520505.1|intact:EBI-28987257	psi-mi:a0a6l7h9c3_bacan(display_long)|uniprotkb:GBAA_5406(locus name)	psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834335|imex:IM-13779-3863	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|refseq:WP_001099975.1|interpro:IPR036388|interpro:IPR036390"	"ensembl:ENSG00000100393.16(gene)|ensembl:ENST00000263253.9(transcript)|ensembl:ENST00000715703.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0000785""(chromatin)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001756""(somitogenesis)|go:""GO:0001966""(thigmotaxis)|go:""GO:0002039""(p53 binding)|go:""GO:0002209""(behavioral defense response)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0004468""(L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006110""(regulation of glycolytic process)|go:""GO:0006473""(protein acetylation)|go:""GO:0006475""(internal protein amino acid acetylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007611""(learning or memory)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010484""(histone H3 acetyltransferase activity)|go:""GO:0010485""(histone H4 acetyltransferase activity)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016407""(acetyltransferase activity)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0018076""(N-terminal peptidyl-lysine acetylation)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0018394""(peptidyl-lysine acetylation)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030324""(lung development)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034212""(protein N-acetyltransferase activity)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0036268""(swimming)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0043627""(response to estrogen)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044013""(histone H2B acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045721""(negative regulation of gluconeogenesis)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060765""(regulation of androgen receptor signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061733""(protein-lysine-acetyltransferase activity)|go:""GO:0061920""(protein propionyltransferase activity)|go:""GO:0061921""(peptidyl-lysine propionylation)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:0090043""(regulation of tubulin deacetylation)|go:""GO:0097157""(pre-mRNA intronic binding)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0106226""(peptide 2-hydroxyisobutyryltransferase activity)|go:""GO:0120301""(""histone lactyltransferase (CoA-dependent) activity"")|go:""GO:0140033""(acetylation-dependent protein binding)|go:""GO:0140065""(peptide butyryltransferase activity)|go:""GO:0140066""(peptidyl-lysine crotonylation)|go:""GO:0140067""(peptidyl-lysine butyrylation)|go:""GO:0140068""(histone crotonyltransferase activity)|go:""GO:0140069""(histone butyryltransferase activity)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:0141002""(histone H4K16 propionyltransferase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1904515""(positive regulation of TORC2 signaling)|go:""GO:2000330""(positive regulation of T-helper 17 cell lineage commitment)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4BHW|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|rcsb pdb:7QGS|rcsb pdb:7SS8|rcsb pdb:7SSK|rcsb pdb:7SZQ|rcsb pdb:7UGI|rcsb pdb:7VHY|rcsb pdb:7VHZ|rcsb pdb:7VI0|rcsb pdb:7W9V|rcsb pdb:7XEZ|rcsb pdb:7XFG|rcsb pdb:8E1D|rcsb pdb:8FVF|rcsb pdb:8GZC|rcsb pdb:8HAG|rcsb pdb:8HAH|rcsb pdb:8HAI|rcsb pdb:8HAJ|rcsb pdb:8HAK|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9701898|reactome:R-HSA-9707616|reactome:R-HSA-9735871|reactome:R-HSA-9759194|reactome:R-HSA-9793380|reactome:R-HSA-9818026|reactome:R-HSA-9818027|reactome:R-HSA-9818028|reactome:R-HSA-9818030|reactome:R-HSA-9818032|reactome:R-HSA-9818035|reactome:R-HSA-9818749|reactome:R-HSA-9819196|reactome:R-HSA-9833109|reactome:R-HSA-9839394|reactome:R-HSA-9841922|refseq:NP_001420.2|efo:""Orphanet:353284""|dip:DIP-257N|panther:PTHR13808(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:RF415biCLiP0aJnqIsNwQXl5DRw1392	rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606	intact-crc:D5DF2CB3100D8335|rigid:SoMPvf4F8SX2Cihtt/UfaaoDuqg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HGH8	uniprotkb:Q9Y227	intact:EBI-2812854|uniprotkb:Q6KMM3|uniprotkb:Q6HTD1|uniprotkb:E9QZR3|uniprotkb:E9QZR4|uniprotkb:A0A2P0HJA3|uniprotkb:Q81LX9	intact:EBI-2834366|uniprotkb:O15092|uniprotkb:D3DSS3|ensembl:ENSP00000351520.4	psi-mi:a0a6l7hgh8_bacan(display_long)|uniprotkb:metI(gene name)|psi-mi:metI(display_short)|uniprotkb:GBAA_4480(locus name)	psi-mi:entp4_human(display_long)|uniprotkb:ENTPD4(gene name)|psi-mi:ENTPD4(display_short)|uniprotkb:KIAA0392(gene name synonym)|uniprotkb:LALP70(gene name synonym)|uniprotkb:LYSAL1(gene name synonym)|uniprotkb:Lysosomal apyrase-like protein of 70 kDa(gene name synonym)|uniprotkb:Uridine-diphosphatase(gene name synonym)|uniprotkb:Golgi UDPase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834363|imex:IM-13779-3864	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000277(Cys/Met metabolism, pyridoxal phosphate-dependent enzyme)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0005737""(cytoplasm)|go:""GO:0016846""(carbon-sulfur lyase activity)|go:""GO:0019346""(transsulfuration)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR054542|refseq:WP_000103893.1"	"refseq:NP_001122402.1|refseq:NP_004892.1|ensembl:ENSG00000197217.13(gene)|ensembl:ENST00000358689.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0004382""(GDP phosphatase activity)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006256""(UDP catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0017110""(nucleoside diphosphate phosphatase activity)|go:""GO:0017111""(ribonucleoside triphosphate phosphatase activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0034656""(nucleobase-containing small molecule catabolic process)|go:""GO:0036384""(CDP phosphatase activity)|go:""GO:0043273""(CTPase activity)|go:""GO:0045134""(UDP phosphatase activity)|go:""GO:0046036""(CTP metabolic process)|go:""GO:0046712""(GDP catabolic process)|go:""GO:1990606""(membrane scission GTPase motor activity)|interpro:IPR000407(Nucleoside phosphatase GDA1/CD39)|rcsb pdb:6WG5|reactome:R-HSA-8850843|panther:PTHR11782(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7joPHBMLoR4JQC0Sb2jnzu9Omy81392	rogid:EKgaG5ip3muWIbGoct8bnZ9mcSM9606	intact-crc:95FEECA57B525C97|rigid:DiZHacv9DELgHKdntlXuI3w4mCE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q09472	uniprotkb:A0A6L8Q0Q2	intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|ensembl:ENSP00000263253.7|ensembl:ENSP00000520505.1|intact:EBI-28987257	intact:EBI-2814500|uniprotkb:Q6HRQ5|uniprotkb:Q6KL19|uniprotkb:E9R161|uniprotkb:E9R162|uniprotkb:Q81KA5|uniprotkb:A0A0F7RAI4	psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym)	psi-mi:a0a6l8q0q2_bacan(display_long)|uniprotkb:GBAA_5099(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834342|imex:IM-13779-3866	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100393.16(gene)|ensembl:ENST00000263253.9(transcript)|ensembl:ENST00000715703.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0000785""(chromatin)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001756""(somitogenesis)|go:""GO:0001966""(thigmotaxis)|go:""GO:0002039""(p53 binding)|go:""GO:0002209""(behavioral defense response)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0004468""(L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006110""(regulation of glycolytic process)|go:""GO:0006473""(protein acetylation)|go:""GO:0006475""(internal protein amino acid acetylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007611""(learning or memory)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010484""(histone H3 acetyltransferase activity)|go:""GO:0010485""(histone H4 acetyltransferase activity)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016407""(acetyltransferase activity)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0018076""(N-terminal peptidyl-lysine acetylation)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0018394""(peptidyl-lysine acetylation)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030324""(lung development)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034212""(protein N-acetyltransferase activity)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0036268""(swimming)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0043627""(response to estrogen)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044013""(histone H2B acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045721""(negative regulation of gluconeogenesis)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060765""(regulation of androgen receptor signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061733""(protein-lysine-acetyltransferase activity)|go:""GO:0061920""(protein propionyltransferase activity)|go:""GO:0061921""(peptidyl-lysine propionylation)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:0090043""(regulation of tubulin deacetylation)|go:""GO:0097157""(pre-mRNA intronic binding)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0106226""(peptide 2-hydroxyisobutyryltransferase activity)|go:""GO:0120301""(""histone lactyltransferase (CoA-dependent) activity"")|go:""GO:0140033""(acetylation-dependent protein binding)|go:""GO:0140065""(peptide butyryltransferase activity)|go:""GO:0140066""(peptidyl-lysine crotonylation)|go:""GO:0140067""(peptidyl-lysine butyrylation)|go:""GO:0140068""(histone crotonyltransferase activity)|go:""GO:0140069""(histone butyryltransferase activity)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:0141002""(histone H4K16 propionyltransferase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1904515""(positive regulation of TORC2 signaling)|go:""GO:2000330""(positive regulation of T-helper 17 cell lineage commitment)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4BHW|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|rcsb pdb:7QGS|rcsb pdb:7SS8|rcsb pdb:7SSK|rcsb pdb:7SZQ|rcsb pdb:7UGI|rcsb pdb:7VHY|rcsb pdb:7VHZ|rcsb pdb:7VI0|rcsb pdb:7W9V|rcsb pdb:7XEZ|rcsb pdb:7XFG|rcsb pdb:8E1D|rcsb pdb:8FVF|rcsb pdb:8GZC|rcsb pdb:8HAG|rcsb pdb:8HAH|rcsb pdb:8HAI|rcsb pdb:8HAJ|rcsb pdb:8HAK|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9701898|reactome:R-HSA-9707616|reactome:R-HSA-9735871|reactome:R-HSA-9759194|reactome:R-HSA-9793380|reactome:R-HSA-9818026|reactome:R-HSA-9818027|reactome:R-HSA-9818028|reactome:R-HSA-9818030|reactome:R-HSA-9818032|reactome:R-HSA-9818035|reactome:R-HSA-9818749|reactome:R-HSA-9819196|reactome:R-HSA-9833109|reactome:R-HSA-9839394|reactome:R-HSA-9841922|refseq:NP_001420.2|efo:""Orphanet:353284""|dip:DIP-257N|panther:PTHR13808(orthology-group)"	"interpro:IPR006337(Pyridoxal phosphate-dependent enzyme, SelA-like)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR018319|go:""GO:0004125""(""L-seryl-tRNA(Sec) selenium transferase activity"")|refseq:WP_000510094.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606	rogid:h386hxiST9zHBPm0BLWIcpTJsD01392	intact-crc:F3C32EB1959ECA35|rigid:ukht36zAODAlviozD97evMCbolg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q09472	uniprotkb:A0A6L7HFV2	intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|ensembl:ENSP00000263253.7|ensembl:ENSP00000520505.1|intact:EBI-28987257	intact:EBI-2818324|uniprotkb:Q6KPE6|uniprotkb:Q6HV74|uniprotkb:E9QVT9|uniprotkb:E9QVU0|uniprotkb:Q81XX7|uniprotkb:A0A0F7RA63	psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym)	psi-mi:a0a6l7hfv2_bacan(display_long)|uniprotkb:GBAA_3787(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834356|imex:IM-13779-3865	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100393.16(gene)|ensembl:ENST00000263253.9(transcript)|ensembl:ENST00000715703.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000123""(histone acetyltransferase complex)|go:""GO:0000785""(chromatin)|go:""GO:0001221""(transcription coregulator binding)|go:""GO:0001223""(transcription coactivator binding)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001756""(somitogenesis)|go:""GO:0001966""(thigmotaxis)|go:""GO:0002039""(p53 binding)|go:""GO:0002209""(behavioral defense response)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004402""(histone acetyltransferase activity)|go:""GO:0004468""(L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006110""(regulation of glycolytic process)|go:""GO:0006473""(protein acetylation)|go:""GO:0006475""(internal protein amino acid acetylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007249""(canonical NF-kappaB signal transduction)|go:""GO:0007399""(nervous system development)|go:""GO:0007507""(heart development)|go:""GO:0007519""(skeletal muscle tissue development)|go:""GO:0007611""(learning or memory)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009887""(animal organ morphogenesis)|go:""GO:0010484""(histone H3 acetyltransferase activity)|go:""GO:0010485""(histone H4 acetyltransferase activity)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0016407""(acetyltransferase activity)|go:""GO:0016746""(acyltransferase activity)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0018076""(N-terminal peptidyl-lysine acetylation)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0018394""(peptidyl-lysine acetylation)|go:""GO:0030183""(B cell differentiation)|go:""GO:0030220""(platelet formation)|go:""GO:0030324""(lung development)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0031648""(protein destabilization)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0032931""(histone H3K56 acetyltransferase activity)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034212""(protein N-acetyltransferase activity)|go:""GO:0034644""(cellular response to UV)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035855""(megakaryocyte development)|go:""GO:0036268""(swimming)|go:""GO:0036408""(histone H3K14 acetyltransferase activity)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0043627""(response to estrogen)|go:""GO:0043923""(positive regulation by host of viral transcription)|go:""GO:0043992""(histone H3K9 acetyltransferase activity)|go:""GO:0043993""(histone H3K18 acetyltransferase activity)|go:""GO:0043994""(histone H3K23 acetyltransferase activity)|go:""GO:0043995""(histone H4K5 acetyltransferase activity)|go:""GO:0043996""(histone H4K8 acetyltransferase activity)|go:""GO:0043997""(histone H4K12 acetyltransferase activity)|go:""GO:0043999""(histone H2AK5 acetyltransferase activity)|go:""GO:0044012""(histone H2AK9 acetyltransferase activity)|go:""GO:0044013""(histone H2B acetyltransferase activity)|go:""GO:0044014""(histone H2BK5 acetyltransferase activity)|go:""GO:0044015""(histone H2BK12 acetyltransferase activity)|go:""GO:0044016""(histone H3K4 acetyltransferase activity)|go:""GO:0044017""(histone H3K27 acetyltransferase activity)|go:""GO:0044018""(histone H3K36 acetyltransferase activity)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045721""(negative regulation of gluconeogenesis)|go:""GO:0045815""(transcription initiation-coupled chromatin remodeling)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046427""(positive regulation of receptor signaling pathway via JAK-STAT)|go:""GO:0046972""(histone H4K16 acetyltransferase activity)|go:""GO:0048156""(tau protein binding)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051059""(NF-kappaB binding)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060765""(regulation of androgen receptor signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0061733""(protein-lysine-acetyltransferase activity)|go:""GO:0061920""(protein propionyltransferase activity)|go:""GO:0061921""(peptidyl-lysine propionylation)|go:""GO:0071233""(cellular response to L-leucine)|go:""GO:0090043""(regulation of tubulin deacetylation)|go:""GO:0097157""(pre-mRNA intronic binding)|go:""GO:0097677""(STAT family protein binding)|go:""GO:0106226""(peptide 2-hydroxyisobutyryltransferase activity)|go:""GO:0120301""(""histone lactyltransferase (CoA-dependent) activity"")|go:""GO:0140033""(acetylation-dependent protein binding)|go:""GO:0140065""(peptide butyryltransferase activity)|go:""GO:0140066""(peptidyl-lysine crotonylation)|go:""GO:0140067""(peptidyl-lysine butyrylation)|go:""GO:0140068""(histone crotonyltransferase activity)|go:""GO:0140069""(histone butyryltransferase activity)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140908""(histone H3K122 acetyltransferase activity)|go:""GO:0141002""(histone H4K16 propionyltransferase activity)|go:""GO:1900034""(regulation of cellular response to heat)|go:""GO:1901796""(regulation of signal transduction by p53 class mediator)|go:""GO:1904263""(positive regulation of TORC1 signaling)|go:""GO:1904515""(positive regulation of TORC2 signaling)|go:""GO:2000330""(positive regulation of T-helper 17 cell lineage commitment)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4BHW|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|rcsb pdb:7QGS|rcsb pdb:7SS8|rcsb pdb:7SSK|rcsb pdb:7SZQ|rcsb pdb:7UGI|rcsb pdb:7VHY|rcsb pdb:7VHZ|rcsb pdb:7VI0|rcsb pdb:7W9V|rcsb pdb:7XEZ|rcsb pdb:7XFG|rcsb pdb:8E1D|rcsb pdb:8FVF|rcsb pdb:8GZC|rcsb pdb:8HAG|rcsb pdb:8HAH|rcsb pdb:8HAI|rcsb pdb:8HAJ|rcsb pdb:8HAK|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9701898|reactome:R-HSA-9707616|reactome:R-HSA-9735871|reactome:R-HSA-9759194|reactome:R-HSA-9793380|reactome:R-HSA-9818026|reactome:R-HSA-9818027|reactome:R-HSA-9818028|reactome:R-HSA-9818030|reactome:R-HSA-9818032|reactome:R-HSA-9818035|reactome:R-HSA-9818749|reactome:R-HSA-9819196|reactome:R-HSA-9833109|reactome:R-HSA-9839394|reactome:R-HSA-9841922|refseq:NP_001420.2|efo:""Orphanet:353284""|dip:DIP-257N|panther:PTHR13808(orthology-group)"	"interpro:IPR027417|interpro:IPR005021(Phage Terminase)|go:""GO:0004519""(endonuclease activity)|refseq:WP_001222618.1|interpro:IPR046461|interpro:IPR046462"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/24	rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606	rogid:iK417DPiQ3Ypjwn5KZjvXuIzx2M1392	intact-crc:77D7EEECC5174CAB|rigid:scYWigou4TgN7jFN3x/+pVzzRu0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HKS5	uniprotkb:P14625	intact:EBI-2826271|uniprotkb:Q6KUI7|uniprotkb:E9R5T6|uniprotkb:A0A2P0HCH6|uniprotkb:Q81SE4	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767.4	psi-mi:a0a6l7hks5_bacan(display_long)|uniprotkb:flhA(gene name)|psi-mi:flhA(display_short)|uniprotkb:GBAA_1716(locus name)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)|uniprotkb:HSPC4(gene name synonym)|uniprotkb:Heat shock protein family C member 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834389|imex:IM-13779-3869	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001712(Type III secretion system FHIPEP)|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|go:""GO:0044780""(bacterial-type flagellum assembly)|refseq:WP_000472548.1|interpro:IPR042193|interpro:IPR042194|interpro:IPR042196"	"panther:PTHR11528(orthology-group)|refseq:NP_003290.1|ensembl:ENSG00000166598.16(gene)|ensembl:ENST00000299767.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030496""(midbody)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|reactome:R-HSA-8957275|go:""GO:0031247""(actin rod assembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033018""(sarcoplasmic reticulum lumen)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042470""(melanosome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051208""(sequestering of calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071287""(cellular response to manganese ion)|go:""GO:0071318""(cellular response to ATP)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|rcsb pdb:7ULL|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|dip:DIP-36060N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:vAmLFbYFEzpdttbrXOEvnTIEK041392	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	intact-crc:A0FE6C9EFDA31F12|rigid:TXvyUu1L377ktlGfY+zCsze4w8A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6H3AEH9	uniprotkb:P14625	intact:EBI-2825969|uniprotkb:Q6KQA7|uniprotkb:Q6HW51|uniprotkb:E9QXA7|uniprotkb:E9QXA8|uniprotkb:Q81MY8|uniprotkb:A0A1S0QZ62	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767.4	psi-mi:a0a6h3aeh9_bacan(display_long)|uniprotkb:GBAA_3431(locus name)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)|uniprotkb:HSPC4(gene name synonym)|uniprotkb:Heat shock protein family C member 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834375|imex:IM-13779-3870	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR004849(6-phosphogluconate dehydrogenase related protein)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|go:""GO:0004616""(""phosphogluconate dehydrogenase (decarboxylating) activity"")|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0016054""(organic acid catabolic process)|go:""GO:0019521""(D-gluconate metabolic process)|go:""GO:0050661""(NADP binding)|refseq:WP_001195906.1|interpro:IPR036291"	"panther:PTHR11528(orthology-group)|refseq:NP_003290.1|ensembl:ENSG00000166598.16(gene)|ensembl:ENST00000299767.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030496""(midbody)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|reactome:R-HSA-8957275|go:""GO:0031247""(actin rod assembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033018""(sarcoplasmic reticulum lumen)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042470""(melanosome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051208""(sequestering of calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071287""(cellular response to manganese ion)|go:""GO:0071318""(cellular response to ATP)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|rcsb pdb:7ULL|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|dip:DIP-36060N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:9xewZtuST2DIssVvl7EmWL6KWz81392	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	intact-crc:F7B1997D439B28BD|rigid:4GXFtKmgQLIb0SfoWV2Rsqw/08I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81VT8	uniprotkb:P14625	intact:EBI-2811891|uniprotkb:Q6I4U2	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767.4	psi-mi:rpob_bacan(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:BA_0102(locus name)|uniprotkb:GBAA_0102(locus name)|uniprotkb:BAS0102(locus name)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)|uniprotkb:HSPC4(gene name synonym)|uniprotkb:Heat shock protein family C member 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834396|imex:IM-13779-3867	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR042107|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001054""(obsolete RNA polymerase I activity)|go:""GO:0001055""(obsolete RNA polymerase II activity)|go:""GO:0001056""(obsolete RNA polymerase III activity)|go:""GO:0001057""(obsolete RNA polymerase IV activity)|go:""GO:0001058""(obsolete RNA polymerase V activity)|go:""GO:0001066""(obsolete plastid single subunit type RNA polymerase activity)|go:""GO:0003677""(DNA binding)|go:""GO:0032549""(ribonucleoside binding)|refseq:WP_000147548.1|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR037034|interpro:IPR037033|refseq:NP_842670.1|refseq:YP_026388.1"	"panther:PTHR11528(orthology-group)|refseq:NP_003290.1|ensembl:ENSG00000166598.16(gene)|ensembl:ENST00000299767.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030496""(midbody)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|reactome:R-HSA-8957275|go:""GO:0031247""(actin rod assembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033018""(sarcoplasmic reticulum lumen)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042470""(melanosome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051208""(sequestering of calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071287""(cellular response to manganese ion)|go:""GO:0071318""(cellular response to ATP)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|rcsb pdb:7ULL|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|dip:DIP-36060N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:JkSWbOKVTslDT4FzfcceEZErpHQ1392	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	intact-crc:FCE883CEEADAB398|rigid:NsmgLgy5WtNpjHk52EMuStB6qDk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P14625	uniprotkb:A0A6L8PG64	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767.4	intact:EBI-2814435|uniprotkb:Q6HVL4|uniprotkb:Q6F097|uniprotkb:E9R0Y6|uniprotkb:E9R0Y7|uniprotkb:A0A2P0HH79|uniprotkb:Q81YC1	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)|uniprotkb:HSPC4(gene name synonym)|uniprotkb:Heat shock protein family C member 4(gene name synonym)	psi-mi:a0a6l8pg64_bacan(display_long)|uniprotkb:GBAA_3631(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834382|imex:IM-13779-3868	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11528(orthology-group)|refseq:NP_003290.1|ensembl:ENSG00000166598.16(gene)|ensembl:ENST00000299767.10(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0003723""(RNA binding)|go:""GO:0004864""(protein phosphatase inhibitor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005790""(smooth endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006457""(protein folding)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030496""(midbody)|go:""GO:0030970""(retrograde protein transport, ER to cytosol)|reactome:R-HSA-8957275|go:""GO:0031247""(actin rod assembly)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033018""(sarcoplasmic reticulum lumen)|go:""GO:0034663""(endoplasmic reticulum chaperone complex)|go:""GO:0034975""(protein folding in endoplasmic reticulum)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042470""(melanosome)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050750""(low-density lipoprotein particle receptor binding)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0051208""(sequestering of calcium ion)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071287""(cellular response to manganese ion)|go:""GO:0071318""(cellular response to ATP)|go:""GO:0071682""(endocytic vesicle lumen)|go:""GO:0097524""(sperm plasma membrane)|go:""GO:0140662""(ATP-dependent protein folding chaperone)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|rcsb pdb:7ULL|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|dip:DIP-36060N"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR001041(Ferredoxin)|interpro:IPR006478(Formate dehydrogenase, alpha subunit)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR019574|interpro:IPR050123|go:""GO:0003954""(NADH dehydrogenase activity)|go:""GO:0008863""(""formate dehydrogenase (NAD+) activity"")|go:""GO:0015942""(formate metabolic process)|go:""GO:0016020""(membrane)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_000794675.1|interpro:IPR036010|interpro:IPR041924"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	rogid:QIgvJ3jy6mN9lKyYhw7Vk06JkC01392	intact-crc:864F540606AF07CA|rigid:Gl7h0KagSl0zKN38TnUyLdGKJ5c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14246	uniprotkb:Q81VT3	intact:EBI-2834430|ensembl:ENSP00000311545.3|uniprotkb:A6NHV2|uniprotkb:Q2I7G5|uniprotkb:Q8NGA7|uniprotkb:B7Z486|uniprotkb:B7Z489|uniprotkb:E7EPX9|uniprotkb:E9PD45|uniprotkb:H9KV79|uniprotkb:Q6ZMN0	intact:EBI-2816582|uniprotkb:Q6KYI3|uniprotkb:Q6I4T7	psi-mi:agre1_human(display_long)|uniprotkb:ADGRE1(gene name)|psi-mi:ADGRE1(display_short)|uniprotkb:EGF-like module receptor 1(gene name synonym)|uniprotkb:EGF-like module-containing mucin-like hormone receptor-like 1(gene name synonym)|uniprotkb:EMR1(gene name synonym)|uniprotkb:EMR1 hormone receptor(gene name synonym)|uniprotkb:TM7LN3(gene name synonym)	psi-mi:efg_bacan(display_long)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)|uniprotkb:BA_0107(locus name)|uniprotkb:GBAA_0107(locus name)|uniprotkb:BAS0107(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834427|imex:IM-13779-3873	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000174837.15(gene)|ensembl:ENST00000312053.9(transcript)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004930""(G protein-coupled receptor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0007155""(cell adhesion)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007189""(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000203(GPS)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR001740(GPCR, family 2, EMR1 hormone receptor)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017981|interpro:IPR017983|interpro:IPR018097|interpro:IPR046338|interpro:IPR049883|reactome:R-HSA-373080|refseq:NP_001965.3|refseq:NP_001243182.1|refseq:NP_001243181.1|refseq:NP_001243183.1|refseq:NP_001243184.1|panther:PTHR12011(orthology-group)"	"interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR031157|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|refseq:WP_000090364.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|refseq:NP_842675.1|refseq:YP_026393.1|interpro:IPR047872"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:q+fWa2LP+Fu9sYuOKdGt7vT5XVY9606	rogid:iKao5O7KH1KI6bGoVf+7AT6g3181392	intact-crc:9BCE54A7F0D624B3|rigid:HajLexD3kgd5LgD+QoKnRiq9w2s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6C2	uniprotkb:Q81P27	intact:EBI-744586|intact:EBI-902920|uniprotkb:A5PL03|uniprotkb:H0Y7A0|uniprotkb:Q53SY9|uniprotkb:Q96G58|uniprotkb:Q96IH6|uniprotkb:Q9UG76|uniprotkb:A0A0C4DFX3|ensembl:ENSP00000369677.4	intact:EBI-2814639|uniprotkb:Q6KRC1|uniprotkb:Q6HX99	psi-mi:emil1_human(display_long)|uniprotkb:EMILIN1(gene name)|psi-mi:EMILIN1(display_short)|uniprotkb:EMI(gene name synonym)|uniprotkb:Elastin microfibril interface-located protein 1(gene name synonym)	psi-mi:proa_bacan(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:BA_2992(locus name)|uniprotkb:GBAA_2992(locus name)|uniprotkb:BAS2781(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834441|imex:IM-13779-3871	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:485418""|dip:DIP-35733N|ensembl:ENSG00000138080.14(gene)|ensembl:ENST00000380320.9(transcript)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005615""(extracellular space)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008217""(regulation of blood pressure)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010811""(positive regulation of cell-substrate adhesion)|go:""GO:0016477""(cell migration)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0030023""(extracellular matrix constituent conferring elasticity)|go:""GO:0030194""(positive regulation of blood coagulation)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030948""(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:""GO:0032966""(negative regulation of collagen biosynthetic process)|go:""GO:0033627""(cell adhesion mediated by integrin)|go:""GO:0034668""(integrin alpha4-beta1 complex)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048251""(elastic fiber assembly)|go:""GO:0050866""(negative regulation of cell activation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060392""(negative regulation of SMAD protein signal transduction)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0098640""(integrin binding involved in cell-matrix adhesion)|go:""GO:1900426""(positive regulation of defense response to bacterium)|go:""GO:1900747""(negative regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1901731""(positive regulation of platelet aggregation)|go:""GO:1904027""(negative regulation of collagen fibril organization)|go:""GO:1905522""(negative regulation of macrophage migration)|go:""GO:1990971""(EMILIN complex)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR011489(EMI)|interpro:IPR050392|mint:Q9Y6C2|rcsb pdb:2KA3|rcsb pdb:2OII|reactome:R-HSA-2129379|refseq:NP_008977.1|panther:PTHR15427(orthology-group)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|go:""GO:0004350""(glutamate-5-semialdehyde dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0050661""(NADP binding)|go:""GO:0055129""(L-proline biosynthetic process)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:NP_845325.1|refseq:YP_029039.1|refseq:WP_001006638.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lJnDOaq3HA5TUGd1Skz/1s3DIxM9606	rogid:2iR76/3cLX7gyVDMLNG2KEyBoMY1392	intact-crc:578663A1804DD70E|rigid:5eDGyqvkVD8hKVGV4rSxNT8o7tw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P06733	uniprotkb:A0A6L7H6C0	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590.4|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-2814287|uniprotkb:Q6I0R3|uniprotkb:Q6KUL9|uniprotkb:E9RCU3|uniprotkb:E9RCU4|uniprotkb:Q81SI0|uniprotkb:A0A0F7RJD1	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:a0a6l7h6c0_bacan(display_long)|uniprotkb:flgK(gene name)|psi-mi:flgK(display_short)|uniprotkb:GBAA_1669(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834403|imex:IM-13779-3874	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800.16(gene)|ensembl:ENST00000234590.10(transcript)|go:""GO:0000015""(phosphopyruvate hydratase complex)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0001222""(transcription corepressor binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004634""(phosphopyruvate hydratase activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005640""(nuclear outer membrane)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0006096""(glycolytic process)|go:""GO:0009615""(response to virus)|go:""GO:0009986""(cell surface)|go:""GO:0010756""(positive regulation of plasminogen activation)|go:""GO:0016020""(membrane)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0031430""(M band)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045296""(cadherin binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045933""(positive regulation of muscle contraction)|go:""GO:0051020""(GTPase binding)|go:""GO:0061621""(canonical glycolysis)|go:""GO:0070062""(extracellular exosome)|go:""GO:1903298""(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:""GO:2001171""(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|panther:PTHR11902(orthology-group)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR053927|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009424""(bacterial-type flagellum hook)|go:""GO:0044780""(bacterial-type flagellum assembly)|refseq:WP_001239678.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:VOkH/wThG14shDsSxBIqKBRImSc1392	intact-crc:6858F7938F005A84|rigid:n1KqHJ0TqdQODsvuyb1u0ZYxoBE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H1G2	uniprotkb:Q96A84	intact:EBI-2809927	intact:EBI-2340062|uniprotkb:B0QYK6|uniprotkb:Q86SS7|uniprotkb:Q6ICG1	psi-mi:a0a6l7h1g2_bacan(display_long)|uniprotkb:BA_3725(locus name)	psi-mi:emid1_human(display_long)|uniprotkb:EMID1(gene name)|psi-mi:EMID1(display_short)|uniprotkb:EMU1(gene name synonym)|uniprotkb:Emilin and multimerin domain-containing protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834448|imex:IM-13779-3872	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR008966(Adhesion, bacterial)|refseq:NP_845988.2|interpro:IPR051172|uniprotkb:A0A2P0HHP2(uniprot-removed-ac)|interpro:IPR047589	"refseq:NP_597712.2|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR011489(EMI)|refseq:NP_001254824.1|interpro:IPR050392|go:""GO:0005576""(extracellular region)|go:""GO:0005581""(collagen trimer)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0031012""(extracellular matrix)|panther:PTHR15427(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uYo4V4gwqrM1aujk7uvGf4SXK1c1392	rogid:kWMVjpIKt3Ga27zQbt3yLsTWl2k9606	intact-crc:BCC3B4E657214C47|rigid:wEfevf0c7QYnDv56uGTWR8qu8UY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N8S7	uniprotkb:D1MPY3	intact:EBI-2834410|uniprotkb:Q5VTQ9|uniprotkb:Q9UFB8|uniprotkb:Q9NVF3|uniprotkb:Q502W5|uniprotkb:Q5T5M7|uniprotkb:Q5VTR0|uniprotkb:D0PQI2|ensembl:ENSP00000355809.2	intact:EBI-63974350	psi-mi:enah_human(display_long)|uniprotkb:ENAH(gene name)|psi-mi:ENAH(display_short)|uniprotkb:MENA(gene name synonym)	psi-mi:d1mpy3_bacan(display_long)|uniprotkb:GBAA_4848(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834420|imex:IM-13779-3875	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001008493.1|refseq:NP_060682.2|ensembl:ENSG00000154380.19(gene)|ensembl:ENST00000366844.7(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0007411""(axon guidance)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030027""(lamellipodium)|go:""GO:0030054""(cell junction)|go:""GO:0030175""(filopodium)|go:""GO:0050699""(WW domain binding)|go:""GO:0070358""(actin polymerization-dependent cell motility)|go:""GO:0098794""(postsynapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0099188""(postsynaptic cytoskeleton organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|mint:Q8N8S7|rcsb pdb:2HO2|rcsb pdb:2IYB|rcsb pdb:2XQN|rcsb pdb:4MY6|rcsb pdb:5N91|rcsb pdb:5N9C|rcsb pdb:5N9P|rcsb pdb:5NAJ|rcsb pdb:5NBF|rcsb pdb:5NBX|rcsb pdb:5NC2|rcsb pdb:5NC7|rcsb pdb:5NCF|rcsb pdb:5NCG|rcsb pdb:5NCP|rcsb pdb:5ND0|rcsb pdb:5NDU|rcsb pdb:5NEG|rcsb pdb:6RCF|rcsb pdb:6RCJ|rcsb pdb:6RD2|rcsb pdb:6XVT|rcsb pdb:6XXR|rcsb pdb:7A5M|rcsb pdb:7AKI|rcsb pdb:7LXE|rcsb pdb:9C66|reactome:R-HSA-202433|reactome:R-HSA-376176|panther:PTHR11202(orthology-group)"	"go:""GO:0004471""(""malate dehydrogenase (decarboxylating) (NAD+) activity"")|go:""GO:0046872""(metal ion binding)|go:""GO:0051287""(NAD binding)|go:""GO:0008948""(oxaloacetate decarboxylase activity)|interpro:IPR046346|interpro:IPR051674|interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR037062|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR045213|interpro:IPR001891(Malic oxidoreductase)|interpro:IPR036291"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/21	rogid:FxcMlDgO3bbl9NRD/z+fDOcdLic9606	rogid:EErQsU3Tj+3HaUDRtvpfD+OD6j01392	intact-crc:55CC3CE644E968A5|rigid:i9exAxOuFm1ApLdchWKGOvcGopA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14241	uniprotkb:Q81WK3	intact:EBI-742350|uniprotkb:Q8IXH1|uniprotkb:B2R7Q8|ensembl:ENSP00000484196.2	intact:EBI-2826194|uniprotkb:Q6KNY5|uniprotkb:Q6HUQ4	psi-mi:eloa1_human(display_long)|uniprotkb:ELOA(gene name)|psi-mi:ELOA(display_short)|uniprotkb:Elongin 110 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit A1(gene name synonym)|uniprotkb:SIII p110(gene name synonym)|uniprotkb:TCEB3(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 3(gene name synonym)|uniprotkb:MSTP059(orf name)	"psi-mi:trmfo_bacan(display_long)|uniprotkb:trmFO(gene name)|psi-mi:trmFO(display_short)|uniprotkb:gid(gene name synonym)|uniprotkb:""Folate-dependent tRNA (uracil-5-)-methyltransferase""(gene name synonym)|uniprotkb:""Folate-dependent tRNA(M-5-U54)-methyltransferase""(gene name synonym)|uniprotkb:BA_3970(locus name)|uniprotkb:GBAA_3970(locus name)|uniprotkb:BAS3683(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834455|imex:IM-13779-3878	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003189.2|ensembl:ENSG00000011007.13(gene)|ensembl:ENST00000613537.5(transcript)|go:""GO:0005615""(extracellular space)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006367""(transcription initiation at RNA polymerase II promoter)|go:""GO:0006368""(transcription elongation by RNA polymerase II)|go:""GO:0070449""(elongin complex)|go:""GO:0090734""(site of DNA damage)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR010684(RNA polymerase II transcription factor SIII, subunit A)|interpro:IPR017923|interpro:IPR035441|interpro:IPR051870|mint:Q14241|rcsb pdb:4HFX|rcsb pdb:6ZUZ|rcsb pdb:8OEV|rcsb pdb:8OEW|rcsb pdb:8OF0|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|panther:PTHR15141(orthology-group)"	"interpro:IPR004417(Gid protein)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0047151""(""tRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent"")|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|interpro:IPR040131|refseq:NP_846213.1|refseq:YP_029934.1|refseq:WP_003161605.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:xkZC1MGlAqFyhLSjBHPJLqawYeI9606	rogid:ZK5+I3fqFuyTXl2yUtsPcns5frI1392	intact-crc:C6584CC29573FC77|rigid:sXoyzxug0+rztjCJXlNdXCkKv+o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81X63	uniprotkb:Q15723	intact:EBI-2824145|uniprotkb:Q6KKB8|uniprotkb:Q6HQZ9	intact:EBI-956941|uniprotkb:E9PCX3|uniprotkb:Q15724|uniprotkb:Q15725|uniprotkb:Q6P1K5|ensembl:ENSP00000368868.1|ensembl:ENSP00000510098.1	psi-mi:clpp2_bacan(display_long)|uniprotkb:clpP2(gene name)|psi-mi:clpP2(display_short)|uniprotkb:Endopeptidase Clp 2(gene name synonym)|uniprotkb:BA_5380(locus name)|uniprotkb:GBAA_5380(locus name)|uniprotkb:BAS5000(locus name)	psi-mi:elf2_human(display_long)|uniprotkb:ELF2(gene name)|psi-mi:ELF2(display_short)|uniprotkb:NERF(gene name synonym)|uniprotkb:E74-like factor 2(gene name synonym)|uniprotkb:New ETS-related factor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834469|imex:IM-13779-3879	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029045|interpro:IPR023562|interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0009368""(endopeptidase Clp complex)|go:""GO:0051117""(ATPase binding)|refseq:WP_001049158.1|refseq:NP_847553.1|refseq:YP_031239.1"	"refseq:NP_001263387.1|refseq:NP_006865.1|refseq:NP_973728.1|refseq:NP_001263386.1|refseq:NP_001263388.1|refseq:XP_005262861.1|ensembl:ENSG00000109381.21(gene)|ensembl:ENST00000379550.5(transcript)|ensembl:ENST00000686138.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR022084|interpro:IPR036388|interpro:IPR036390|interpro:IPR046328|mint:Q15723|reactome:R-HSA-8939245|refseq:NP_001317965.1|panther:PTHR11849(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GOdNsLkhwlnAg7HzjXKmi0tPu041392	rogid:I+5r30P0sfIJfJSYkJwjpbWxUnE9606	intact-crc:65DF9D3F6C82E897|rigid:Sbc9HBmZAfB3tUM0Uaj2EAVQihk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P32519	uniprotkb:Q81VT3	intact:EBI-765526|uniprotkb:Q9UDE1|uniprotkb:Q8N6F6|ensembl:ENSP00000239882.3|uniprotkb:B4E2I5|uniprotkb:E9PDQ9	intact:EBI-2816582|uniprotkb:Q6KYI3|uniprotkb:Q6I4T7	psi-mi:elf1_human(display_long)|uniprotkb:E74-like factor 1(gene name synonym)|uniprotkb:ELF1(gene name)|psi-mi:ELF1(display_short)	psi-mi:efg_bacan(display_long)|uniprotkb:fusA(gene name)|psi-mi:fusA(display_short)|uniprotkb:BA_0107(locus name)|uniprotkb:GBAA_0107(locus name)|uniprotkb:BAS0107(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834483|imex:IM-13779-3880	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_758961.1|ensembl:ENSG00000120690.17(gene)|ensembl:ENST00000239882.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR022084|interpro:IPR036388|interpro:IPR036390|interpro:IPR046328|mint:P32519|rcsb pdb:8BZM|reactome:R-HSA-8939245|reactome:R-HSA-8939247|refseq:NP_001138825.1|refseq:XP_005266333.1|refseq:XP_005266334.1|refseq:XP_011533252.1|refseq:XP_016875898.1|refseq:XP_016875899.1|refseq:XP_016875900.1|refseq:XP_016875901.1|refseq:XP_016875902.1|dip:DIP-185N|panther:PTHR11849(orthology-group)"	"interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR031157|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032790""(ribosome disassembly)|refseq:WP_000090364.1|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|refseq:NP_842675.1|refseq:YP_026393.1|interpro:IPR047872"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bkNv2VvMBvrmLtvw8qhFrj9Zgqg9606	rogid:iKao5O7KH1KI6bGoVf+7AT6g3181392	intact-crc:C7BD98753E15FD35|rigid:1CB9f6O48xEQdRCoc5ajK2Senr0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q81LS0	uniprotkb:Q92556	intact:EBI-2819530|uniprotkb:Q6HT75|uniprotkb:Q6KMG5	intact:EBI-346417|uniprotkb:Q29R79|uniprotkb:Q96PB0|uniprotkb:Q9H0I1|uniprotkb:A4D1X6|uniprotkb:Q6ZTJ0|ensembl:ENSP00000312185.4|ensembl:ENSP00000394458.1|ensembl:ENSP00000406952.1	psi-mi:hrca_bacan(display_long)|uniprotkb:hrcA(gene name)|psi-mi:hrcA(display_short)|uniprotkb:BA_4541(locus name)|uniprotkb:GBAA_4541(locus name)|uniprotkb:BAS4215(locus name)	psi-mi:elmo1_human(display_long)|uniprotkb:ELMO1(gene name)|psi-mi:ELMO1(display_short)|uniprotkb:KIAA0281(gene name synonym)|uniprotkb:Protein ced-12 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834462|imex:IM-13779-3877	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002571(Negative regulator of class I heat shock protein)|interpro:IPR021153|interpro:IPR029016|go:""GO:0003677""(DNA binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR023120|interpro:IPR036388|interpro:IPR036390|refseq:NP_846764.1|refseq:YP_030463.1|refseq:WP_000954959.1"	"refseq:XP_006715868.1|refseq:NP_569709.1|refseq:XP_005249976.1|refseq:NP_001034548.1|refseq:NP_001193409.1|refseq:NP_001193411.1|refseq:NP_055615.8|refseq:XP_011513956.1|refseq:XP_016868327.1|refseq:XP_016868328.1|dip:DIP-31095N|panther:PTHR12771(orthology-group)|ensembl:ENSG00000155849.16(gene)|ensembl:ENST00000310758.9(transcript)|ensembl:ENST00000442504.5(transcript)|ensembl:ENST00000448602.5(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006911""(phagocytosis, engulfment)|go:""GO:0006915""(apoptotic process)|go:""GO:0007015""(actin filament organization)|go:""GO:0016020""(membrane)|go:""GO:0016601""(Rac protein signal transduction)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0032045""(guanyl-nucleotide exchange factor complex)|go:""GO:0048870""(cell motility)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0150052""(regulation of postsynapse assembly)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR050868|mint:Q92556|rcsb pdb:2RQR|rcsb pdb:2VSZ|rcsb pdb:3A98|rcsb pdb:6JPP|rcsb pdb:6TGB|rcsb pdb:6TGC|rcsb pdb:7DPA|rcsb pdb:7Y4A|rcsb pdb:8JHK|rcsb pdb:8XM7|rcsb pdb:8ZJ2|rcsb pdb:8ZJI|rcsb pdb:8ZJJ|rcsb pdb:8ZJK|rcsb pdb:8ZJL|rcsb pdb:8ZJM|reactome:R-HSA-164944|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9664422"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FxNDUbF2tI63G+uoXAqPrmi7I2s1392	rogid:sW9Vj+Vej/oJb9qQxkbtIipDYXI9606	intact-crc:3EB1261FCD7D6CE6|rigid:EL9Gcg1xO0T7n53EXQGTopqV2cI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P32519	uniprotkb:Q81VQ2	intact:EBI-765526|uniprotkb:Q9UDE1|uniprotkb:Q8N6F6|ensembl:ENSP00000239882.3|uniprotkb:B4E2I5|uniprotkb:E9PDQ9	intact:EBI-2825506|uniprotkb:Q6I4Q5|uniprotkb:Q6KYF1	psi-mi:elf1_human(display_long)|uniprotkb:E74-like factor 1(gene name synonym)|uniprotkb:ELF1(gene name)|psi-mi:ELF1(display_short)	psi-mi:ecfa1_bacan(display_long)|uniprotkb:ecfA1(gene name)|psi-mi:ecfA1(display_short)|uniprotkb:BA_0139(locus name)|uniprotkb:GBAA_0139(locus name)|uniprotkb:BAS0139(locus name)|uniprotkb:cbiO1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834476|imex:IM-13779-3876	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_758961.1|ensembl:ENSG00000120690.17(gene)|ensembl:ENST00000239882.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050860""(negative regulation of T cell receptor signaling pathway)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR022084|interpro:IPR036388|interpro:IPR036390|interpro:IPR046328|mint:P32519|rcsb pdb:8BZM|reactome:R-HSA-8939245|reactome:R-HSA-8939247|refseq:NP_001138825.1|refseq:XP_005266333.1|refseq:XP_005266334.1|refseq:XP_011533252.1|refseq:XP_016875898.1|refseq:XP_016875899.1|refseq:XP_016875900.1|refseq:XP_016875901.1|refseq:XP_016875902.1|dip:DIP-185N|panther:PTHR11849(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR015856(ABC transporter, cobalt import, CbiO)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR030947|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|refseq:WP_000711776.1|interpro:IPR050095|refseq:NP_842707.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bkNv2VvMBvrmLtvw8qhFrj9Zgqg9606	rogid:wV6ZuuadhxEfPKjJLolCzTI9zX41392	intact-crc:4E0898753E482D4E|rigid:NElI2Iblw7he0KffHePdN3bOpas	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HGW3	uniprotkb:Q14152	intact:EBI-2818336|uniprotkb:Q6KN08|uniprotkb:Q6HTS0|uniprotkb:E9RDF4|uniprotkb:E9RDF5|uniprotkb:Q81MB8|uniprotkb:A0A2B6C356	intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|uniprotkb:B4DYS1|uniprotkb:F5H335|ensembl:ENSP00000358140.3	psi-mi:a0a6l7hgw3_bacan(display_long)|uniprotkb:ribD(gene name)|psi-mi:ribD(display_short)|uniprotkb:GBAA_4331(locus name)	psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834518|imex:IM-13779-3881	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_000131964.1|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024072|interpro:IPR004794(Riboflavin biosynthesis protein RibD)|interpro:IPR011549(Riboflavin-specific deaminase, C-terminal)|interpro:IPR002734(Bacterial bifunctional deaminase-reductase, C-terminal)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008703""(""5-amino-6-(5-phosphoribosylamino)uracil reductase activity"")|go:""GO:0008835""(diaminohydroxyphosphoribosylaminopyrimidine deaminase activity)|go:""GO:0009231""(riboflavin biosynthetic process)|go:""GO:0050661""(NADP binding)|interpro:IPR050765"	"panther:PTHR14005(orthology-group)|refseq:NP_003741.1|ensembl:ENSG00000107581.14(gene)|ensembl:ENST00000369144.8(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0002188""(translation reinitiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0043614""(multi-eIF complex)|go:""GO:0071540""(eukaryotic translation initiation factor 3 complex, eIF3e)|go:""GO:0071541""(eukaryotic translation initiation factor 3 complex, eIF3m)|go:""GO:0075522""(IRES-dependent viral translational initiation)|go:""GO:0075525""(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|interpro:IPR054711|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8RG0|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:qyyX3f46kyi+OF7x/SOuXvVgloQ1392	rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606	intact-crc:74D3DF65C270644E|rigid:P9Ndn/nMuIrcbHMI0lgQiR9kSeM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6KMS8	uniprotkb:Q7L2H7	intact:EBI-2812678|uniprotkb:Q81M34|uniprotkb:Q6HTI7	intact:EBI-353901|intact:EBI-4289539|intact:EBI-715219|uniprotkb:Q2F836|uniprotkb:Q53HL6|uniprotkb:Q9BXW1|uniprotkb:O60735|ensembl:ENSP00000436049.1|uniprotkb:A8K7X4|intact:EBI-2559366|intact:EBI-373200|uniprotkb:B4E2Q4	psi-mi:efp_bacan(display_long)|uniprotkb:efp(gene name)|psi-mi:efp(display_short)|uniprotkb:BA_4421(locus name)|uniprotkb:GBAA_4421(locus name)|uniprotkb:BAS4101(locus name)	psi-mi:eif3m_human(display_long)|uniprotkb:EIF3M(gene name)|psi-mi:EIF3M(display_short)|uniprotkb:HFLB5(gene name synonym)|uniprotkb:PCID1(gene name synonym)|uniprotkb:PCI domain-containing protein 1(gene name synonym)|uniprotkb:Fetal lung protein B5(gene name synonym)|uniprotkb:GA17(orf name)|uniprotkb:PNAS-125(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834511|imex:IM-13779-3884	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015365(Elongation factor P, C-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR020599|interpro:IPR013185(Translation elongation factor, KOW-like)|interpro:IPR001059(Translation elongation factor P/YeiP, central)|interpro:IPR013852(Translation elongation factor P/YeiP, conserved site)|interpro:IPR011768(Translation elongation factor P)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0043043""(peptide biosynthetic process)|refseq:WP_000626507.1|refseq:YP_030351.1|refseq:NP_846649.1"	"refseq:NP_006351.2|ensembl:ENSG00000149100.13(gene)|ensembl:ENST00000531120.6(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0071541""(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027528|interpro:IPR036390|interpro:IPR040750|interpro:IPR045237|mint:Q7L2H7|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8RG0|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001294858.1|dip:DIP-31256N|panther:PTHR15350(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/30	rogid:IbRpaP4LNDHuGJwbXfefgJ5Xgc81392	rogid:siTfTDezqWL90pw6xG3xUKfY9n49606	intact-crc:E8A74B0E87CB0252|rigid:XXIMfCJpHfP/d148p01A7BVIw/U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6KMS8	uniprotkb:Q9HBU6	intact:EBI-2812678|uniprotkb:Q81M34|uniprotkb:Q6HTI7	intact:EBI-2834493|ensembl:ENSP00000500633.1|uniprotkb:G5E969	psi-mi:efp_bacan(display_long)|uniprotkb:efp(gene name)|psi-mi:efp(display_short)|uniprotkb:BA_4421(locus name)|uniprotkb:GBAA_4421(locus name)|uniprotkb:BAS4101(locus name)	psi-mi:eki1_human(display_long)|uniprotkb:ETNK1(gene name)|psi-mi:ETNK1(display_short)|uniprotkb:EKI1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834490|imex:IM-13779-3883	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR015365(Elongation factor P, C-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR020599|interpro:IPR013185(Translation elongation factor, KOW-like)|interpro:IPR001059(Translation elongation factor P/YeiP, central)|interpro:IPR013852(Translation elongation factor P/YeiP, conserved site)|interpro:IPR011768(Translation elongation factor P)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0043043""(peptide biosynthetic process)|refseq:WP_000626507.1|refseq:YP_030351.1|refseq:NP_846649.1"	"ensembl:ENSG00000139163.16(gene)|ensembl:ENST00000671733.1(transcript)|go:""GO:0004305""(ethanolamine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006646""(phosphatidylethanolamine biosynthetic process)|go:""GO:0016020""(membrane)|interpro:IPR011009(Protein kinase-like)|reactome:R-HSA-1483213|refseq:NP_001034570.1|refseq:NP_061108.2|panther:PTHR22603(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IbRpaP4LNDHuGJwbXfefgJ5Xgc81392	rogid:XgPFI/UFFpkwS7Ta86qngfvtAtc9606	intact-crc:B1D370A041197D17|rigid:do8vbUCiY9OdyAnoKxuurM5jsCw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7L2H7	uniprotkb:Q9X367	intact:EBI-353901|intact:EBI-4289539|intact:EBI-715219|uniprotkb:Q2F836|uniprotkb:Q53HL6|uniprotkb:Q9BXW1|uniprotkb:O60735|ensembl:ENSP00000436049.1|uniprotkb:A8K7X4|intact:EBI-2559366|intact:EBI-373200|uniprotkb:B4E2Q4	intact:EBI-2834504|uniprotkb:A0A0F7RN48	psi-mi:eif3m_human(display_long)|uniprotkb:EIF3M(gene name)|psi-mi:EIF3M(display_short)|uniprotkb:HFLB5(gene name synonym)|uniprotkb:PCID1(gene name synonym)|uniprotkb:PCI domain-containing protein 1(gene name synonym)|uniprotkb:Fetal lung protein B5(gene name synonym)|uniprotkb:GA17(orf name)|uniprotkb:PNAS-125(orf name)	psi-mi:q9x367_bacan(display_long)|uniprotkb:GBAA_pXO1_0190(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834501|imex:IM-13779-3882	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006351.2|ensembl:ENSG00000149100.13(gene)|ensembl:ENST00000531120.6(transcript)|go:""GO:0001732""(formation of cytoplasmic translation initiation complex)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005829""(cytosol)|go:""GO:0005852""(eukaryotic translation initiation factor 3 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0016282""(eukaryotic 43S preinitiation complex)|go:""GO:0031369""(translation initiation factor binding)|go:""GO:0033290""(eukaryotic 48S preinitiation complex)|go:""GO:0071541""(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027528|interpro:IPR036390|interpro:IPR040750|interpro:IPR045237|mint:Q7L2H7|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|rcsb pdb:7QP6|rcsb pdb:7QP7|rcsb pdb:8OZ0|rcsb pdb:8PJ1|rcsb pdb:8PJ2|rcsb pdb:8PJ3|rcsb pdb:8PJ4|rcsb pdb:8PJ5|rcsb pdb:8PJ6|rcsb pdb:8PPL|rcsb pdb:8RG0|rcsb pdb:8XXN|rcsb pdb:9BLN|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001294858.1|dip:DIP-31256N|panther:PTHR15350(orthology-group)"	interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR024696|refseq:NP_052794.1|refseq:WP_000107153.1|interpro:IPR036689	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/12/30	rogid:siTfTDezqWL90pw6xG3xUKfY9n49606	rogid:Y3xlSSocAJhe9IdrrPf/p/uFGYY1392	intact-crc:6711B1745BAC04F3|rigid:iHbo/ND7TOd50EYwxzwn7OWO2Uk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14232	uniprotkb:Q81Z95	intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|ensembl:ENSP00000416250.2|uniprotkb:B4DGX0	intact:EBI-2834561|uniprotkb:Q6KXU7|uniprotkb:Q6I437	psi-mi:ei2ba_human(display_long)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym)|uniprotkb:eIF2B GDP-GTP exchange factor subunit alpha(gene name synonym)	psi-mi:thie_bacan(display_long)|uniprotkb:thiE(gene name)|psi-mi:thiE(display_short)|uniprotkb:Thiamine-phosphate pyrophosphorylase(gene name synonym)|uniprotkb:BAS0363(locus name)|uniprotkb:BA_0377(locus name)|uniprotkb:GBAA_0377(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834558|imex:IM-13779-3888	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:157713""|efo:""Orphanet:157716""|efo:""Orphanet:157719""|efo:""Orphanet:99853""|efo:""Orphanet:99854""|ensembl:ENSG00000111361.13(gene)|ensembl:ENST00000424014.7(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005851""(eukaryotic translation initiation factor 2B complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0009408""(response to heat)|go:""GO:0009749""(response to glucose)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|interpro:IPR051501|mint:Q14232|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7F64|rcsb pdb:7F66|rcsb pdb:7F67|rcsb pdb:7KMA|rcsb pdb:7KMF|rcsb pdb:7L70|rcsb pdb:7L7G|rcsb pdb:7RLO|rcsb pdb:7TRJ|rcsb pdb:7VLK|rcsb pdb:8TQZ|reactome:R-HSA-72731|refseq:NP_001405.1|panther:PTHR45860(orthology-group)"	"refseq:NP_842921.1|refseq:YP_026643.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004789""(thiamine-phosphate diphosphorylase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR022998|interpro:IPR034291|refseq:WP_000086975.1|interpro:IPR036206"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606	rogid:wBZ9Uggl1xAmQ8/liVbE+SfzS581392	intact-crc:236B5030D2818BED|rigid:gvRpaCNzE0rvsfBS0CgzecVjReU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BY44	uniprotkb:A0A6L7HRV6	intact:EBI-1776615|uniprotkb:Q5QTR2|uniprotkb:Q7Z4E9|uniprotkb:Q8NFM1|uniprotkb:Q96EW9|uniprotkb:Q96K81|uniprotkb:A8MPS6|uniprotkb:D3DNI9|uniprotkb:B4DF96|uniprotkb:B4DQ14|ensembl:ENSP00000417229.1	intact:EBI-2832416|uniprotkb:Q6KXT9|uniprotkb:Q6I429|uniprotkb:E9R386|uniprotkb:E9R387|uniprotkb:A0A2P0H9C3|uniprotkb:Q81Z87	psi-mi:eif2a_human(display_long)|uniprotkb:EIF2A(gene name)|psi-mi:EIF2A(display_short)|uniprotkb:CDA02(orf name)|uniprotkb:MSTP004(orf name)|uniprotkb:MSTP089(orf name)|uniprotkb:65 kDa eukaryotic translation initiation factor 2A(gene name synonym)	psi-mi:a0a6l7hrv6_bacan(display_long)|uniprotkb:GBAA_0385(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834525|imex:IM-13779-3890	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_114414.2|refseq:NP_001305972.1|refseq:NP_001305973.1|refseq:NP_001305974.1|refseq:NP_001305975.1|dip:DIP-40272N|ensembl:ENSG00000144895.12(gene)|ensembl:ENST00000460851.6(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0005850""(eukaryotic translation initiation factor 2 complex)|go:""GO:0006413""(translational initiation)|go:""GO:0006417""(regulation of translation)|go:""GO:0009967""(positive regulation of signal transduction)|go:""GO:0022627""(cytosolic small ribosomal subunit)|go:""GO:0032933""(SREBP signaling pathway)|go:""GO:0042255""(ribosome assembly)|go:""GO:0043022""(ribosome binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0072562""(blood microparticle)|go:""GO:1990928""(response to amino acid starvation)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9BY44|rcsb pdb:8DYS|panther:PTHR13227(orthology-group)"	"interpro:IPR008965(Carbohydrate-binding)|interpro:IPR001919(Cellulose-binding, family II, bacterial type)|interpro:IPR011583(Chitinase II)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR001579(Glycoside hydrolase, chitinase active site)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029070|refseq:WP_000837181.1|go:""GO:0004568""(chitinase activity)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0008061""(chitin binding)|go:""GO:0030247""(polysaccharide binding)|interpro:IPR012291(Cellulose-binding family II/chitobiase, carbohydrate-binding)|interpro:IPR036116|interpro:IPR050314"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/17	rogid:67hYEz0CrhoQ7SfXxZdOWqKzil89606	rogid:I4hK26GFIM7C8r3ZgujTjMnow6w1392	intact-crc:1547691458742F00|rigid:OzgIS9A1HR2EHyCUEFVJS5fJ6cM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L8PKT5	uniprotkb:Q14232	intact:EBI-2813319|uniprotkb:Q6HSQ9|uniprotkb:Q6KM00|uniprotkb:E9R0U8|uniprotkb:E9R0U9|uniprotkb:Q81LA5|uniprotkb:A0A2B6C7G8	intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|ensembl:ENSP00000416250.2|uniprotkb:B4DGX0	psi-mi:a0a6l8pkt5_bacan(display_long)|uniprotkb:GBAA_4721(locus name)	psi-mi:ei2ba_human(display_long)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym)|uniprotkb:eIF2B GDP-GTP exchange factor subunit alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834532|imex:IM-13779-3885	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001233029.1|interpro:IPR001647(Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal)|interpro:IPR009057(Homeodomain-like)|go:""GO:0003677""(DNA binding)"	"efo:""Orphanet:157713""|efo:""Orphanet:157716""|efo:""Orphanet:157719""|efo:""Orphanet:99853""|efo:""Orphanet:99854""|ensembl:ENSG00000111361.13(gene)|ensembl:ENST00000424014.7(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005851""(eukaryotic translation initiation factor 2B complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0009408""(response to heat)|go:""GO:0009749""(response to glucose)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|interpro:IPR051501|mint:Q14232|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7F64|rcsb pdb:7F66|rcsb pdb:7F67|rcsb pdb:7KMA|rcsb pdb:7KMF|rcsb pdb:7L70|rcsb pdb:7L7G|rcsb pdb:7RLO|rcsb pdb:7TRJ|rcsb pdb:7VLK|rcsb pdb:8TQZ|reactome:R-HSA-72731|refseq:NP_001405.1|panther:PTHR45860(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eMc+DhH/fXvBQcctpTt+PKe0QmE1392	rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606	intact-crc:D0A7F0F6377B6908|rigid:fNYtvBkRjfRL+2Hp+z8eJyFAuko	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7HQF1	uniprotkb:Q14232	intact:EBI-2834546|uniprotkb:A0A0J1HRC5|uniprotkb:Q6I432|uniprotkb:Q6KXU2|uniprotkb:E9QRB5|uniprotkb:E9QRB6|uniprotkb:Q81Z90	intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|ensembl:ENSP00000416250.2|uniprotkb:B4DGX0	psi-mi:a0a6l7hqf1_bacan(display_long)|uniprotkb:GBAA_0382(locus name)	psi-mi:ei2ba_human(display_long)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym)|uniprotkb:eIF2B GDP-GTP exchange factor subunit alpha(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834551|imex:IM-13779-3887	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0009228""(thiamine biosynthetic process)|interpro:IPR015168(NMT1/THI5 like)|interpro:IPR027939|refseq:WP_000715551.1"	"efo:""Orphanet:157713""|efo:""Orphanet:157716""|efo:""Orphanet:157719""|efo:""Orphanet:99853""|efo:""Orphanet:99854""|ensembl:ENSG00000111361.13(gene)|ensembl:ENST00000424014.7(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005851""(eukaryotic translation initiation factor 2B complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0009408""(response to heat)|go:""GO:0009749""(response to glucose)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|interpro:IPR051501|mint:Q14232|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7F64|rcsb pdb:7F66|rcsb pdb:7F67|rcsb pdb:7KMA|rcsb pdb:7KMF|rcsb pdb:7L70|rcsb pdb:7L7G|rcsb pdb:7RLO|rcsb pdb:7TRJ|rcsb pdb:7VLK|rcsb pdb:8TQZ|reactome:R-HSA-72731|refseq:NP_001405.1|panther:PTHR45860(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YZvoN1N3KdU6ajw2+RLpZDGK2Dw1392	rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606	intact-crc:D9F900966E8D2813|rigid:PB3j24DI//hHYZrntxRkvfx/FEI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14232	uniprotkb:Q81W03	intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|ensembl:ENSP00000416250.2|uniprotkb:B4DGX0	intact:EBI-2816847|uniprotkb:Q6I506|uniprotkb:Q6KYQ0	psi-mi:ei2ba_human(display_long)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym)|uniprotkb:eIF2B GDP-GTP exchange factor subunit alpha(gene name synonym)	psi-mi:sym1_bacan(display_long)|uniprotkb:metG1(gene name)|psi-mi:metG1(display_short)|uniprotkb:metG(gene name synonym)|uniprotkb:metS(gene name synonym)|uniprotkb:BA_0036(locus name)|uniprotkb:GBAA_0036(locus name)|uniprotkb:BAS0037(locus name)|uniprotkb:Methionyl-tRNA synthetase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834571|imex:IM-13779-3886	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:157713""|efo:""Orphanet:157716""|efo:""Orphanet:157719""|efo:""Orphanet:99853""|efo:""Orphanet:99854""|ensembl:ENSG00000111361.13(gene)|ensembl:ENST00000424014.7(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005851""(eukaryotic translation initiation factor 2B complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0009408""(response to heat)|go:""GO:0009749""(response to glucose)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|interpro:IPR051501|mint:Q14232|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7F64|rcsb pdb:7F66|rcsb pdb:7F67|rcsb pdb:7KMA|rcsb pdb:7KMF|rcsb pdb:7L70|rcsb pdb:7L7G|rcsb pdb:7RLO|rcsb pdb:7TRJ|rcsb pdb:7VLK|rcsb pdb:8TQZ|reactome:R-HSA-72731|refseq:NP_001405.1|panther:PTHR45860(orthology-group)"	"interpro:IPR015413(""Aminoacyl-tRNA synthetase, class I (M)"")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004495(Methionyl-tRNA synthetase, class Ia, beta subunit, C-terminal)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023457|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|go:""GO:0000049""(tRNA binding)|go:""GO:0004825""(methionine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006431""(methionyl-tRNA aminoacylation)|interpro:IPR033911|interpro:IPR041872|refseq:NP_842605.1|refseq:YP_026324.1|refseq:WP_000134128.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606	rogid:UV6NoFqVLKRIPMXdNWd52Fysfxg1392	intact-crc:76D16D30D3493036|rigid:gPJaa2662od32j3WUNxfH8PYyxs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14232	uniprotkb:A0A6L7HHX2	intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|ensembl:ENSP00000416250.2|uniprotkb:B4DGX0	intact:EBI-2812285|uniprotkb:Q6KUB0|uniprotkb:Q6I0E0|uniprotkb:E9QSI8|uniprotkb:E9QSI9|uniprotkb:Q81S59|uniprotkb:A0A0F7RKM4	psi-mi:ei2ba_human(display_long)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym)|uniprotkb:eIF2B GDP-GTP exchange factor subunit alpha(gene name synonym)	psi-mi:a0a6l7hhx2_bacan(display_long)|uniprotkb:GBAA_1815(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834539|imex:IM-13779-3889	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:157713""|efo:""Orphanet:157716""|efo:""Orphanet:157719""|efo:""Orphanet:99853""|efo:""Orphanet:99854""|ensembl:ENSG00000111361.13(gene)|ensembl:ENST00000424014.7(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005851""(eukaryotic translation initiation factor 2B complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0009408""(response to heat)|go:""GO:0009749""(response to glucose)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|interpro:IPR051501|mint:Q14232|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7F64|rcsb pdb:7F66|rcsb pdb:7F67|rcsb pdb:7KMA|rcsb pdb:7KMF|rcsb pdb:7L70|rcsb pdb:7L7G|rcsb pdb:7RLO|rcsb pdb:7TRJ|rcsb pdb:7VLK|rcsb pdb:8TQZ|reactome:R-HSA-72731|refseq:NP_001405.1|panther:PTHR45860(orthology-group)"	"interpro:IPR025450|go:""GO:0016020""(membrane)|refseq:WP_000789548.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606	rogid:g0iSNc7Mh4tgNaBj+nHYsEjH5sY1392	intact-crc:4AF1FB69A78BE70F|rigid:6Z9WpO8f9/UIAM7oXGm/wTYdwoQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N3D4	uniprotkb:A0A6L7H5Z1	intact:EBI-2834588|ensembl:ENSP00000312671.4|uniprotkb:Q8TB89|uniprotkb:Q9H7M7	intact:EBI-2814937|uniprotkb:Q6KUU5|uniprotkb:Q6I0Z1|uniprotkb:E9RAI4|uniprotkb:E9RAI5|uniprotkb:Q81SQ9|uniprotkb:A0A0F7RGX0	psi-mi:eh1l1_human(display_long)|uniprotkb:EHBP1L1(gene name)|psi-mi:EHBP1L1(display_short)	psi-mi:a0a6l7h5z1_bacan(display_long)|uniprotkb:GBAA_1587(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834585|imex:IM-13779-3892	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000173442.13(gene)|ensembl:ENST00000309295.9(transcript)|go:""GO:0005768""(endosome)|go:""GO:0016020""(membrane)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR019448|interpro:IPR022735|interpro:IPR036872|interpro:IPR050540|mint:Q8N3D4|refseq:NP_001092879.1|panther:PTHR23167(orthology-group)"	"interpro:IPR001333(Peptidase M32, carboxypeptidase Taq metallopeptidase)|go:""GO:0004181""(metallocarboxypeptidase activity)|go:""GO:0006508""(proteolysis)|go:""GO:0046872""(metal ion binding)|refseq:WP_000215091.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:A49ma5uVQHbpAMd99czZVg2Kkfw9606	rogid:lPgMSgTzMiZ8C3peUoF0QYHP7r81392	intact-crc:CC19B893E7F1E573|rigid:1gkmmLpV3adU8H4pmxe9K+0gsXI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P18146	uniprotkb:A0A6H3AED5	intact:EBI-2834611|ensembl:ENSP00000239938.4	intact:EBI-2834615|uniprotkb:A0A0F7R8T9|uniprotkb:Q6KJJ5|uniprotkb:Q6HQ52|uniprotkb:E9QV77|uniprotkb:E9QV78|uniprotkb:Q81JK9	psi-mi:egr1_human(display_long)|uniprotkb:EGR1(gene name)|psi-mi:EGR1(display_short)|uniprotkb:KROX24(gene name synonym)|uniprotkb:ZNF225(gene name synonym)|uniprotkb:AT225(gene name synonym)|uniprotkb:Nerve growth factor-induced protein A(gene name synonym)|uniprotkb:Transcription factor ETR103(gene name synonym)|uniprotkb:Transcription factor Zif268(gene name synonym)|uniprotkb:Zinc finger protein 225(gene name synonym)|uniprotkb:Zinc finger protein Krox-24(gene name synonym)	psi-mi:a0a6h3aed5_bacan(display_long)|uniprotkb:GBAA_5695(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834620|imex:IM-13779-3893	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000120738.8(gene)|ensembl:ENST00000239938.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001666""(response to hypoxia)|go:""GO:0002931""(response to ischemia)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009749""(response to glucose)|go:""GO:0010385""(double-stranded methylated DNA binding)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0030217""(T cell differentiation)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032868""(response to insulin)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0033233""(regulation of protein sumoylation)|go:""GO:0035035""(histone acetyltransferase binding)|go:""GO:0035914""(skeletal muscle cell differentiation)|go:""GO:0043523""(regulation of neuron apoptotic process)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0044029""(positive regulation of gene expression via chromosomal CpG island demethylation)|go:""GO:0044729""(hemi-methylated DNA-binding)|go:""GO:0044849""(estrous cycle)|go:""GO:0045475""(locomotor rhythm)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046886""(positive regulation of hormone biosynthetic process)|go:""GO:0060086""(circadian temperature homeostasis)|go:""GO:0070498""(interleukin-1-mediated signaling pathway)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0071504""(cellular response to heparin)|go:""GO:0071506""(cellular response to mycophenolic acid)|go:""GO:0072110""(glomerular mesangial cell proliferation)|go:""GO:0072303""(positive regulation of glomerular metanephric mesangial cell proliferation)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:0098759""(cellular response to interleukin-8)|go:""GO:1901875""(positive regulation of post-translational protein modification)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:2000182""(regulation of progesterone biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR021839|interpro:IPR021849|interpro:IPR036236|mint:P18146|rcsb pdb:4R2A|rcsb pdb:4R2C|rcsb pdb:4R2D|rcsb pdb:4X9J|rcsb pdb:5N14|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-909733|refseq:NP_001955.1|panther:PTHR23235(orthology-group)"	"go:""GO:0004517""(nitric-oxide synthase activity)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0020037""(heme binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR017142(Nitric oxide synthase, oxygenase subunit)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|refseq:WP_000047612.1|interpro:IPR036119|interpro:IPR050607|interpro:IPR044940|interpro:IPR044943|interpro:IPR044944"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7JnUP8JJaEG/d72DbadDN/gibQ89606	rogid:q4FWQfreIiWagJMuFD7XWadalGc1392	intact-crc:CEB3F0CE3EA99BEA|rigid:jTiyDyWBJwSnG1/OPD06Zs51o/I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N3D4	uniprotkb:A0A6L8NVI6	intact:EBI-2834588|ensembl:ENSP00000312671.4|uniprotkb:Q8TB89|uniprotkb:Q9H7M7	intact:EBI-2834602|uniprotkb:A0A0F7RIW4|uniprotkb:Q6KUC7|uniprotkb:Q6I0G0|uniprotkb:E9R9N5|uniprotkb:E9R9N6|uniprotkb:Q81S78	psi-mi:eh1l1_human(display_long)|uniprotkb:EHBP1L1(gene name)|psi-mi:EHBP1L1(display_short)	psi-mi:a0a6l8nvi6_bacan(display_long)|uniprotkb:GBAA_1792(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834599|imex:IM-13779-3891	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000173442.13(gene)|ensembl:ENST00000309295.9(transcript)|go:""GO:0005768""(endosome)|go:""GO:0016020""(membrane)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR019448|interpro:IPR022735|interpro:IPR036872|interpro:IPR050540|mint:Q8N3D4|refseq:NP_001092879.1|panther:PTHR23167(orthology-group)"	"go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0016020""(membrane)|go:""GO:0046983""(protein dimerization activity)|interpro:IPR011712(Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region)|refseq:WP_000397669.1|interpro:IPR036890|interpro:IPR050482"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:A49ma5uVQHbpAMd99czZVg2Kkfw9606	rogid:0PcwF6wqZNuTsGsmw2tMbNQycjE1392	intact-crc:91C87B3469F8AC4D|rigid:CmHIkUZZYcYiLLjjfo4PaPUJFLQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14232	uniprotkb:A0A6L7H165	intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|ensembl:ENSP00000416250.2|uniprotkb:B4DGX0	intact:EBI-2811597|uniprotkb:Q6KPI1|uniprotkb:Q6HVB3|uniprotkb:E9QV35|uniprotkb:E9QV36|uniprotkb:A0A2P0HHN5|uniprotkb:Q81Y15	psi-mi:ei2ba_human(display_long)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym)|uniprotkb:eIF2B GDP-GTP exchange factor subunit alpha(gene name synonym)	psi-mi:a0a6l7h165_bacan(display_long)|uniprotkb:GBAA_3744(locus name)|uniprotkb:tkt2(gene name)|psi-mi:tkt2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834578|imex:IM-13779-3894	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:157713""|efo:""Orphanet:157716""|efo:""Orphanet:157719""|efo:""Orphanet:99853""|efo:""Orphanet:99854""|ensembl:ENSG00000111361.13(gene)|ensembl:ENST00000424014.7(transcript)|go:""GO:0002183""(cytoplasmic translational initiation)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005851""(eukaryotic translation initiation factor 2B complex)|go:""GO:0005886""(plasma membrane)|go:""GO:0006413""(translational initiation)|go:""GO:0009408""(response to heat)|go:""GO:0009749""(response to glucose)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0016020""(membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043434""(response to peptide hormone)|go:""GO:0050852""(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|interpro:IPR051501|mint:Q14232|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7F64|rcsb pdb:7F66|rcsb pdb:7F67|rcsb pdb:7KMA|rcsb pdb:7KMF|rcsb pdb:7L70|rcsb pdb:7L7G|rcsb pdb:7RLO|rcsb pdb:7TRJ|rcsb pdb:7VLK|rcsb pdb:8TQZ|reactome:R-HSA-72731|refseq:NP_001405.1|panther:PTHR45860(orthology-group)"	"interpro:IPR033247|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR020826|interpro:IPR005474(Transketolase, N-terminal)|rcsb pdb:3M49|interpro:IPR029061|go:""GO:0004802""(transketolase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0046872""(metal ion binding)|interpro:IPR055152|refseq:WP_000019755.1|rcsb pdb:3HYL|interpro:IPR049557"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606	rogid:/3w4Fmuo2N06ZcrbsjphHSbI8do1392	intact-crc:519770DDB91162EA|rigid:dAfl35zlj1vqKRAA+8d3bY4w4XE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UHF1	uniprotkb:A0A6L7H5N1	intact:EBI-949532|uniprotkb:Q5M7Y5|uniprotkb:Q5VUD5|uniprotkb:Q96EG0|uniprotkb:B3KRP0|uniprotkb:M9VTX9|ensembl:ENSP00000307843.7|ensembl:ENSP00000360763.3|ensembl:ENSP00000360764.1|ensembl:ENSP00000385639.3	intact:EBI-2809887|uniprotkb:Q6KUR8|uniprotkb:Q6I0W2|uniprotkb:E9R1F1|uniprotkb:E9R1F2|uniprotkb:Q81SN0	psi-mi:egfl7_human(display_long)|uniprotkb:Multiple epidermal growth factor-like domains protein 7(gene name synonym)|uniprotkb:Zneu1(gene name synonym)|uniprotkb:Vascular endothelial statin(gene name synonym)|uniprotkb:NOTCH4-like protein(gene name synonym)|uniprotkb:EGFL7(gene name)|psi-mi:EGFL7(display_short)|uniprotkb:MEGF7(gene name synonym)|uniprotkb:UNQ187/PRO1449(orf name)	psi-mi:a0a6l7h5n1_bacan(display_long)|uniprotkb:GBAA_1618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834655|imex:IM-13779-3895	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057299.1|refseq:NP_958854.1|refseq:XP_011517066.1|refseq:XP_011517067.1|refseq:XP_011517068.1|ensembl:ENSG00000172889.16(gene)|ensembl:ENST00000308874.12(transcript)|ensembl:ENST00000371698.3(transcript)|ensembl:ENST00000371699.5(transcript)|ensembl:ENST00000406555.7(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001568""(blood vessel development)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0009986""(cell surface)|go:""GO:0045746""(negative regulation of Notch signaling pathway)|go:""GO:0062023""(collagen-containing extracellular matrix)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011489(EMI)|interpro:IPR013111(EGF, extracellular)|interpro:IPR018097|interpro:IPR050969|mint:Q9UHF1|panther:PTHR14949(orthology-group)"	interpro:IPR008966(Adhesion, bacterial)|interpro:IPR001434(Protein of unknown function DUF11)|interpro:IPR051172|refseq:WP_001123106.1|interpro:IPR047589	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HzaJXQm4JE8bXXE+/ugmqGjpjZA9606	rogid:MkmZVeUMWWo6NHdj3/0js/2MA+01392	intact-crc:3F2CC63059F2A4F6|rigid:tgzRFpIctdnVRozAMzICI4rM9Io	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P00533	uniprotkb:A0A6L7H280	intact:EBI-297353|uniprotkb:Q9BZS2|uniprotkb:Q9GZX1|uniprotkb:Q9H2C9|uniprotkb:Q9H3C9|uniprotkb:Q9UMD7|uniprotkb:Q9UMD8|uniprotkb:Q9UMG5|uniprotkb:O00688|uniprotkb:O00732|uniprotkb:P06268|uniprotkb:Q14225|uniprotkb:Q92795|intact:EBI-28985169|uniprotkb:Q68GS5|ensembl:ENSP00000275493.2	intact:EBI-2810080|uniprotkb:Q6HWG1|uniprotkb:Q6KQK9|uniprotkb:E9R333|uniprotkb:E9R334|uniprotkb:A0A2P0HGI7|uniprotkb:Q81NA2	psi-mi:egfr_human(display_long)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:ERBB(gene name synonym)|uniprotkb:HER1(gene name synonym)	psi-mi:a0a6l7h280_bacan(display_long)|uniprotkb:hypF(gene name)|psi-mi:hypF(display_short)|uniprotkb:GBAA_3313(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834648|imex:IM-13779-3897	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000146648.21(gene)|ensembl:ENST00000275493.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001503""(ossification)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001892""(embryonic placenta development)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001942""(hair follicle development)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0004709""(MAP kinase kinase kinase activity)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005178""(integrin binding)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005768""(endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006412""(translation)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007173""(epidermal growth factor receptor signaling pathway)|go:""GO:0007435""(salivary gland morphogenesis)|go:""GO:0007494""(midgut development)|go:""GO:0007611""(learning or memory)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0016101""(diterpenoid metabolic process)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019900""(kinase binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0021795""(cerebral cortex cell migration)|go:""GO:0022008""(neurogenesis)|go:""GO:0030054""(cell junction)|go:""GO:0030296""(protein tyrosine kinase activator activity)|go:""GO:0030307""(positive regulation of cell growth)|go:""GO:0030324""(lung development)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031965""(nuclear membrane)|go:""GO:0032587""(ruffle membrane)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033138""(positive regulation of peptidyl-serine phosphorylation)|go:""GO:0033590""(response to cobalamin)|go:""GO:0033594""(response to hydroxyisoflavone)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0038083""(peptidyl-tyrosine autophosphorylation)|go:""GO:0038134""(ERBB2-EGFR signaling pathway)|go:""GO:0042059""(negative regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0042177""(negative regulation of protein catabolic process)|go:""GO:0042311""(vasodilation)|go:""GO:0042327""(positive regulation of phosphorylation)|go:""GO:0042698""(ovulation cycle)|go:""GO:0042743""(hydrogen peroxide metabolic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043235""(receptor complex)|go:""GO:0043586""(tongue development)|go:""GO:0045121""(membrane raft)|go:""GO:0045296""(cadherin binding)|go:""GO:0045737""(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0045739""(positive regulation of DNA repair)|go:""GO:0045740""(positive regulation of DNA replication)|go:""GO:0045780""(positive regulation of bone resorption)|go:""GO:0045907""(positive regulation of vasoconstriction)|go:""GO:0045930""(negative regulation of mitotic cell cycle)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048143""(astrocyte activation)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048408""(epidermal growth factor binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048546""(digestive tract morphogenesis)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048812""(neuron projection morphogenesis)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050730""(regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0051015""(actin filament binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051205""(protein insertion into membrane)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0051968""(positive regulation of synaptic transmission, glutamatergic)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060252""(positive regulation of glial cell proliferation)|go:""GO:0060571""(morphogenesis of an epithelial fold)|go:""GO:0061029""(eyelid development in camera-type eye)|go:""GO:0070141""(response to UV-A)|go:""GO:0070257""(positive regulation of mucus secretion)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070435""(Shc-EGFR complex)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071392""(cellular response to estradiol stimulus)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097060""(synaptic membrane)|go:""GO:0097421""(liver regeneration)|go:""GO:0097489""(multivesicular body, internal vesicle lumen)|go:""GO:0097708""(intracellular vesicle)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1900020""(positive regulation of protein kinase C activity)|go:""GO:1900087""(positive regulation of G1/S transition of mitotic cell cycle)|go:""GO:1902722""(positive regulation of prolactin secretion)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905208""(negative regulation of cardiocyte differentiation)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|interpro:IPR049328|interpro:IPR050122|mint:P00533|rcsb pdb:1IVO|rcsb pdb:1M14|rcsb pdb:1M17|rcsb pdb:1MOX|rcsb pdb:1NQL|rcsb pdb:1XKK|rcsb pdb:1YY9|rcsb pdb:1Z9I|rcsb pdb:2EB2|rcsb pdb:2EB3|rcsb pdb:2GS2|rcsb pdb:2GS6|rcsb pdb:2GS7|rcsb pdb:2ITN|rcsb pdb:2ITO|rcsb pdb:2ITP|rcsb pdb:2ITQ|rcsb pdb:2ITT|rcsb pdb:2ITU|rcsb pdb:2ITV|rcsb pdb:2ITW|rcsb pdb:2ITX|rcsb pdb:2ITY|rcsb pdb:2ITZ|rcsb pdb:2KS1|rcsb pdb:2J5E|rcsb pdb:2J5F|rcsb pdb:2J6M|rcsb pdb:2JIT|rcsb pdb:2JIU|rcsb pdb:2JIV|rcsb pdb:2M0B|rcsb pdb:2M20|rcsb pdb:2N5S|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:2RGP|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BEL|rcsb pdb:3BUO|rcsb pdb:3C09|rcsb pdb:3G5V|rcsb pdb:3G5Y|rcsb pdb:3GOP|rcsb pdb:3GT8|rcsb pdb:3IKA|rcsb pdb:3LZB|rcsb pdb:3NJP|rcsb pdb:3OB2|rcsb pdb:3OP0|rcsb pdb:3P0Y|rcsb pdb:3PFV|rcsb pdb:3POZ|rcsb pdb:3QWQ|rcsb pdb:3UG1|rcsb pdb:3UG2|rcsb pdb:3VJN|rcsb pdb:3VJO|rcsb pdb:3VRP|rcsb pdb:3VRR|rcsb pdb:3W2O|rcsb pdb:3W2P|rcsb pdb:3W2Q|rcsb pdb:3W2R|rcsb pdb:3W2S|rcsb pdb:3W32|rcsb pdb:3W33|rcsb pdb:4G5J|rcsb pdb:4G5P|rcsb pdb:4HJO|rcsb pdb:4I1Z|rcsb pdb:4I20|rcsb pdb:4I21|rcsb pdb:4I22|rcsb pdb:4I23|rcsb pdb:4I24|rcsb pdb:4JQ7|rcsb pdb:4JQ8|rcsb pdb:4JR3|rcsb pdb:4JRV|rcsb pdb:4KRL|rcsb pdb:4KRM|rcsb pdb:4KRO|rcsb pdb:4KRP|rcsb pdb:4LI5|rcsb pdb:4LL0|rcsb pdb:4LQM|rcsb pdb:4LRM|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4R5S|rcsb pdb:4RIW|rcsb pdb:4RIX|rcsb pdb:4RIY|rcsb pdb:4RJ4|rcsb pdb:4RJ5|rcsb pdb:4RJ6|rcsb pdb:4RJ7|rcsb pdb:4RJ8|rcsb pdb:4TKS|rcsb pdb:4UIP|rcsb pdb:4UV7|rcsb pdb:4WD5|rcsb pdb:4WKQ|rcsb pdb:4WRG|rcsb pdb:4ZAU|rcsb pdb:4ZJV|rcsb pdb:4ZSE|rcsb pdb:5C8K|rcsb pdb:5C8M|rcsb pdb:5C8N|rcsb pdb:5CAL|rcsb pdb:5CAN|rcsb pdb:5CAO|rcsb pdb:5CAP|rcsb pdb:5CAQ|rcsb pdb:5CAS|rcsb pdb:5CAU|rcsb pdb:5CAV|rcsb pdb:5CNN|rcsb pdb:5CNO|rcsb pdb:5CZH|rcsb pdb:5CZI|rcsb pdb:5D41|rcsb pdb:5EDP|rcsb pdb:5EDQ|rcsb pdb:5EDR|rcsb pdb:5EM5|rcsb pdb:5EM6|rcsb pdb:5EM7|rcsb pdb:5EM8|rcsb pdb:5FED|rcsb pdb:5FEE|rcsb pdb:5FEQ|rcsb pdb:5GMP|rcsb pdb:5GNK|rcsb pdb:5GTY|rcsb pdb:5GTZ|rcsb pdb:5HCX|rcsb pdb:5HCY|rcsb pdb:5HCZ|rcsb pdb:5HG5|rcsb pdb:5HG7|rcsb pdb:5HG8|rcsb pdb:5HG9|rcsb pdb:5HIB|rcsb pdb:5HIC|rcsb pdb:5J9Y|rcsb pdb:5J9Z|rcsb pdb:5JEB|rcsb pdb:5LV6|rcsb pdb:5SX4|rcsb pdb:5SX5|rcsb pdb:5U8L|rcsb pdb:5UG8|rcsb pdb:5UG9|rcsb pdb:5UGA|rcsb pdb:5UGB|rcsb pdb:5UGC|rcsb pdb:5UWD|rcsb pdb:5WB7|rcsb pdb:5WB8|rcsb pdb:5X26|rcsb pdb:5X27|rcsb pdb:5X28|rcsb pdb:5X2A|rcsb pdb:5X2C|rcsb pdb:5X2F|rcsb pdb:5X2K|rcsb pdb:5XDK|rcsb pdb:5XDL|rcsb pdb:5XGM|rcsb pdb:5XGN|rcsb pdb:5XWD|rcsb pdb:5Y25|rcsb pdb:5Y9T|rcsb pdb:5YU9|rcsb pdb:5ZTO|rcsb pdb:5ZWJ|rcsb pdb:6ARU|rcsb pdb:6B3S|rcsb pdb:6D8E|rcsb pdb:6DUK|rcsb pdb:6JRJ|rcsb pdb:6JRK|rcsb pdb:6JRX|rcsb pdb:6JWL|rcsb pdb:6JX0|rcsb pdb:6JX4|rcsb pdb:6JXT|rcsb pdb:6JZ0|rcsb pdb:6LUB|rcsb pdb:6LUD|rcsb pdb:6P1D|rcsb pdb:6P1L|rcsb pdb:6P8Q|rcsb pdb:6S89|rcsb pdb:6S8A|rcsb pdb:6S9B|rcsb pdb:6S9C|rcsb pdb:6S9D|rcsb pdb:6TFU|rcsb pdb:6TFV|rcsb pdb:6TFW|rcsb pdb:6TFY|rcsb pdb:6TFZ|rcsb pdb:6TG0|rcsb pdb:6TG1|rcsb pdb:6V5N|rcsb pdb:6V5P|rcsb pdb:6V66|rcsb pdb:6V6K|rcsb pdb:6V6O|rcsb pdb:6VH4|rcsb pdb:6VHN|rcsb pdb:6VHP|rcsb pdb:6WA2|rcsb pdb:6WAK|rcsb pdb:6WXN|rcsb pdb:6XL4|rcsb pdb:6Z4B|rcsb pdb:6Z4D|rcsb pdb:7A2A|rcsb pdb:7A6I|rcsb pdb:7A6J|rcsb pdb:7A6K|rcsb pdb:7AEI|rcsb pdb:7AEM|rcsb pdb:7B85|rcsb pdb:7ER2|rcsb pdb:7JXI|rcsb pdb:7JXK|rcsb pdb:7JXL|rcsb pdb:7JXM|rcsb pdb:7JXP|rcsb pdb:7JXQ|rcsb pdb:7JXW|rcsb pdb:7K1H|rcsb pdb:7K1I|rcsb pdb:7KXZ|rcsb pdb:7KY0|rcsb pdb:7LEN|rcsb pdb:7LFR|rcsb pdb:7LFS|rcsb pdb:7LG8|rcsb pdb:7LGS|rcsb pdb:7LTX|rcsb pdb:7OM4|rcsb pdb:7OXB|rcsb pdb:7SI1|rcsb pdb:7SYD|rcsb pdb:7SYE|rcsb pdb:7SZ0|rcsb pdb:7SZ1|rcsb pdb:8A2B|rcsb pdb:7SZ5|rcsb pdb:7SZ7|rcsb pdb:7T4I|rcsb pdb:7T4J|rcsb pdb:7TVD|rcsb pdb:7U98|rcsb pdb:7U99|rcsb pdb:7U9A|rcsb pdb:7UKV|rcsb pdb:7UKW|rcsb pdb:7VRA|rcsb pdb:7VRE|rcsb pdb:7ZYM|rcsb pdb:7ZYN|rcsb pdb:7ZYP|rcsb pdb:7ZYQ|rcsb pdb:8A27|rcsb pdb:8A2A|rcsb pdb:8A2D|rcsb pdb:8D73|rcsb pdb:8D76|rcsb pdb:8DSW|rcsb pdb:8EME|rcsb pdb:8F1H|rcsb pdb:8F1W|rcsb pdb:8F1X|rcsb pdb:8F1Y|rcsb pdb:8F1Z|rcsb pdb:8FV3|rcsb pdb:8FV4|rcsb pdb:8G63|rcsb pdb:8GB4|rcsb pdb:8GK5|rcsb pdb:8H7X|rcsb pdb:8HGO|rcsb pdb:8HGP|rcsb pdb:8HGS|rcsb pdb:8HV1|rcsb pdb:8HV2|rcsb pdb:8HV3|rcsb pdb:8HV4|rcsb pdb:8HV5|rcsb pdb:8HV6|rcsb pdb:8HV7|rcsb pdb:8HV8|rcsb pdb:8HV9|rcsb pdb:8HVA|rcsb pdb:8HY7|rcsb pdb:8KFQ|rcsb pdb:8PNZ|rcsb pdb:8PO0|rcsb pdb:8PO1|rcsb pdb:8PO2|rcsb pdb:8PO3|rcsb pdb:8PO4|rcsb pdb:8S1M|rcsb pdb:8SC7|rcsb pdb:8TJL|rcsb pdb:8TO3|rcsb pdb:8TO4|rcsb pdb:8UKV|rcsb pdb:8UKW|rcsb pdb:8UKX|rcsb pdb:8WD4|rcsb pdb:9EWT|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-212718|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-445144|reactome:R-HSA-5637810|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8857538|reactome:R-HSA-8863795|reactome:R-HSA-8866910|reactome:R-HSA-9009391|reactome:R-HSA-9013507|reactome:R-HSA-9609690|reactome:R-HSA-9634638|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9820960|refseq:NP_005219.2|refseq:NP_958439.1|refseq:NP_958440.1|refseq:NP_958441.1|dip:DIP-405N|efo:""Orphanet:251576""|efo:""Orphanet:251579""|efo:""Orphanet:294023""|ensembl:ENSP00000275493.2|ensembl:ENST00000342916.7|ensembl:ENSP00000342376.3|ensembl:ENST00000344576.7|ensembl:ENSP00000345973.2|ensembl:ENST00000420316.6|ensembl:ENSP00000413843.2|panther:PTHR24416(orthology-group)"	"refseq:WP_000755925.1|interpro:IPR001792(Acylphosphatase)|interpro:IPR017968|interpro:IPR004421(Hydrogenase maturation factor, HypF-type)|interpro:IPR017945|interpro:IPR006070(SUA5/yciO/yrdC, N-terminal)|interpro:IPR011125(Zinc finger, HypF-type)|interpro:IPR051060|interpro:IPR043129|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003998""(acylphosphatase activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016743""(carboxyl- or carbamoyltransferase activity)|go:""GO:0016874""(ligase activity)|go:""GO:0051604""(protein maturation)|interpro:IPR055128|interpro:IPR036046|interpro:IPR041440"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:gXB5slVTC+z8DdqqXIzXG7lDwk09606	rogid:NiJgcEgsdw62qLQJeO1ER4HUq4s1392	intact-crc:AAF4BFF056FAFF3B|rigid:0Ex3rWyLM2k2g/0lMucyVuLooBU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P13639	uniprotkb:A0A6H3AMU8	intact:EBI-352560|uniprotkb:A0A384N6H1|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940.5	intact:EBI-2834665|uniprotkb:A0A2B6BX39|uniprotkb:Q6KMQ5|uniprotkb:Q6HTG3|uniprotkb:E9R1K7|uniprotkb:E9R1K8|uniprotkb:Q81M10|uniprotkb:A0A2A9AL64	psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym)	psi-mi:a0a6h3amu8_bacan(display_long)|uniprotkb:GBAA_4445(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834662|imex:IM-13779-3898	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000167658.16(gene)|ensembl:ENST00000309311.7(transcript)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003746""(translation elongation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005840""(ribosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006414""(translational elongation)|go:""GO:0016020""(membrane)|go:""GO:0016235""(aggresome)|go:""GO:0019901""(protein kinase binding)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0043022""(ribosome binding)|go:""GO:0045202""(synapse)|go:""GO:0045296""(cadherin binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0070062""(extracellular exosome)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:8XSX|rcsb pdb:8Y0W|rcsb pdb:8Y0X|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725|refseq:NP_001952.1|efo:""Orphanet:101112""|panther:PTHR42908(orthology-group)"	"go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR000524(Bacterial regulatory protein GntR, HTH)|refseq:WP_001021341.1|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606	rogid:iixpIyTmX5NhH7MvXSEy5FoIOjo1392	intact-crc:513CADA8BAE535CB|rigid:2BkrzluETkGggosFejhdzn5i7xo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6L7H421	uniprotkb:P17813	intact:EBI-2810652|uniprotkb:Q6KSG7|uniprotkb:Q6HYF9|uniprotkb:E9R9F4|uniprotkb:E9R9F5|uniprotkb:Q81Q87|uniprotkb:A0A0F7RDV9	intact:EBI-2834630|ensembl:ENSP00000362299.4|uniprotkb:Q5T9C0|uniprotkb:Q14248|uniprotkb:Q14926	psi-mi:a0a6l7h421_bacan(display_long)|uniprotkb:GBAA_2546(locus name)	psi-mi:egln_human(display_long)|uniprotkb:ENG(gene name)|psi-mi:ENG(display_short)|uniprotkb:END(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2834641|imex:IM-13779-3899	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR013560(Protein of unknown function DUF1722)|interpro:IPR007553(Protein of unknown function DUF523)|interpro:IPR017087(Uncharacterised conserved protein UCP037004)|refseq:WP_001248630.1	"ensembl:ENSG00000106991.15(gene)|ensembl:ENST00000373203.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001569""(branching involved in blood vessel morphogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001937""(negative regulation of endothelial cell proliferation)|go:""GO:0001947""(heart looping)|go:""GO:0003084""(positive regulation of systemic arterial blood pressure)|go:""GO:0003148""(outflow tract septum morphogenesis)|go:""GO:0003198""(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:""GO:0003203""(endocardial cushion morphogenesis)|go:""GO:0003208""(cardiac ventricle morphogenesis)|go:""GO:0003209""(cardiac atrium morphogenesis)|go:""GO:0003222""(ventricular trabecula myocardium morphogenesis)|go:""GO:0003273""(cell migration involved in endocardial cushion formation)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005114""(type II transforming growth factor beta receptor binding)|go:""GO:0005534""(galactose binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007155""(cell adhesion)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016477""(cell migration)|go:""GO:0016604""(nuclear body)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0022009""(central nervous system vasculogenesis)|go:""GO:0022617""(extracellular matrix disassembly)|go:""GO:0030155""(regulation of cell adhesion)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030513""(positive regulation of BMP signaling pathway)|go:""GO:0030546""(signaling receptor activator activity)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0035912""(dorsal aorta morphogenesis)|go:""GO:0042060""(wound healing)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042325""(regulation of phosphorylation)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043235""(receptor complex)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048185""(activin binding)|go:""GO:0048745""(smooth muscle tissue development)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0048845""(venous blood vessel morphogenesis)|go:""GO:0048870""(cell motility)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055009""(atrial cardiac muscle tissue morphogenesis)|go:""GO:0060326""(cell chemotaxis)|go:""GO:0060348""(bone development)|go:""GO:0060391""(positive regulation of SMAD protein signal transduction)|go:""GO:0060392""(negative regulation of SMAD protein signal transduction)|go:""GO:0070278""(extracellular matrix constituent secretion)|go:""GO:0070483""(detection of hypoxia)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0072563""(endothelial microparticle)|go:""GO:0097084""(vascular associated smooth muscle cell development)|go:""GO:1905007""(positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation)|go:""GO:1905065""(positive regulation of vascular associated smooth muscle cell differentiation)|go:""GO:1905222""(atrioventricular canal morphogenesis)|mint:P17813|rcsb pdb:5HZV|rcsb pdb:5HZW|rcsb pdb:5I04|refseq:NP_000109.1|refseq:NP_001108225.1|refseq:NP_001265067.1|efo:""Orphanet:231160""|efo:""Orphanet:275777""|efo:""Orphanet:329971""|efo:""Orphanet:774""|dip:DIP-6246N|panther:PTHR14002(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S1|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/22	rogid:2helogO2D/G85c/K2apFD3gNVOc1392	rogid:6+7wUY8XztGVcjgbUlGaRjvBIK89606	intact-crc:57F813BD1FCD8D3B|rigid:JJoNgjOCIZ37upy4HDduRqGPRPA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GWC9	uniprotkb:Q9BXK5	intact:EBI-2843839|uniprotkb:Q74W87|uniprotkb:Q0WHN6|uniprotkb:Q7CH71|uniprotkb:A0A380PMJ5|uniprotkb:A0A384L6J2	intact:EBI-747430|uniprotkb:Q96B37|uniprotkb:Q96IB7|uniprotkb:Q9BY01|uniprotkb:Q9HC05|uniprotkb:Q9UFE0|uniprotkb:Q9UKN3|ensembl:ENSP00000318883.5|uniprotkb:B3KPE7	psi-mi:a0a2u2gwc9_yerpe(display_long)|uniprotkb:YPO1163(locus name)	psi-mi:b2l13_human(display_long)|uniprotkb:Protein Mil1(gene name synonym)|uniprotkb:Bcl-rambo(gene name synonym)|uniprotkb:BCL2L13(gene name)|psi-mi:BCL2L13(display_short)|uniprotkb:MIL1(gene name synonym)|uniprotkb:CD003(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848552|imex:IM-13779-5272	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006214(Protein of unknown function UPF0005)|go:""GO:0005886""(plasma membrane)|refseq:WP_002210775.1|refseq:YP_002346202.1"	"refseq:NP_056182.2|ensembl:ENSG00000099968.18(gene)|ensembl:ENST00000317582.10(transcript)|go:""GO:0000423""(mitophagy)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0006119""(oxidative phosphorylation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008656""(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:""GO:0016020""(membrane)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0061621""(canonical glycolysis)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR036834|interpro:IPR042398|interpro:IPR046371|mint:Q9BXK5|dip:DIP-60895N|refseq:NP_001257658.1|refseq:NP_001257659.1|refseq:NP_001257660.1|refseq:XP_011544423.1|refseq:XP_016884217.1|refseq:XP_016884218.1|refseq:XP_016884219.1|refseq:XP_016884220.1|refseq:XP_016884221.1|refseq:XP_016884222.1|panther:PTHR15758(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:G/SUVVMs8jq0JZU6UAMEXR32lzI632	rogid:CTVG9Xyunw/XyOeGX4zYaSXdo6Y9606	intact-crc:D548665A8DC3AD9E|rigid:z6NO1pLHhqn/WpHF4K18K/J9S6E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46379	uniprotkb:A0A6B3V840	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	intact:EBI-2848526	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:a0a6b3v840_yerpe(display_long)|uniprotkb:NCTC5923_01638(orf name)|uniprotkb:y2689(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848523|imex:IM-13779-5270	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"uniprotkb:A0A6B3T7P3(uniprot-removed-ac)|go:""GO:0016020""(membrane)|refseq:WP_002211935.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rogid:W7zomugvi/HnvoJThX94UNnX6sw632	intact-crc:118C060C75C12048|rigid:KjiVJ/V43u4E6jtf5Ph+lq5ISTE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YB62	uniprotkb:P46379	intact:EBI-2844412|uniprotkb:Q74RA2|uniprotkb:Q0WAD3|uniprotkb:Q7CKZ7|uniprotkb:A0A0H2W7C0|uniprotkb:A0A384KQ85	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|ensembl:ENSP00000354368.5|ensembl:ENSP00000390966.2|ensembl:ENSP00000397894.2|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4	psi-mi:a0a5p8yb62_yerpe(display_long)|uniprotkb:YPO3879(locus name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848533|imex:IM-13779-5273	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR018030|interpro:IPR025885|interpro:IPR025949|interpro:IPR043142|refseq:WP_002211999.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR042186|interpro:IPR037224|refseq:YP_002348755.1"	"ensembl:ENSG00000096155.15(gene)|ensembl:ENSG00000229524.10(gene)|ensembl:ENSG00000233348.10(gene)|ensembl:ENST00000361076.9(transcript)|ensembl:ENST00000449450.6(transcript)|ensembl:ENST00000451932.6(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0002429""(immune response-activating cell surface receptor signaling pathway)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006325""(chromatin organization)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006620""(post-translational protein targeting to endoplasmic reticulum membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007130""(synaptonemal complex assembly)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007420""(brain development)|go:""GO:0010498""(proteasomal protein catabolic process)|go:""GO:0016020""(membrane)|go:""GO:0018393""(internal peptidyl-lysine acetylation)|go:""GO:0030101""(natural killer cell activation)|go:""GO:0030154""(cell differentiation)|go:""GO:0030324""(lung development)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0036503""(ERAD pathway)|go:""GO:0036506""(maintenance of unfolded protein)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0042802""(identical protein binding)|go:""GO:0043022""(ribosome binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045861""(negative regulation of proteolysis)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0048018""(receptor ligand activity)|go:""GO:0050821""(protein stabilization)|go:""GO:0051132""(NK T cell activation)|go:""GO:0051787""(misfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061857""(endoplasmic reticulum stress-induced pre-emptive quality control)|go:""GO:0070059""(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070628""(proteasome binding)|go:""GO:0071816""(tail-anchored membrane protein insertion into ER membrane)|go:""GO:0071818""(BAT3 complex)|go:""GO:0140677""(molecular function activator activity)|go:""GO:1904294""(positive regulation of ERAD pathway)|go:""GO:1990381""(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|interpro:IPR048926|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:4X86|rcsb pdb:6AU8|rcsb pdb:7RU9|rcsb pdb:7RUA|rcsb pdb:7RUC|reactome:R-HSA-9609523|dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|panther:PTHR15204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LoLtCTl+KcIEJlQnZYPeOB8LOg4632	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:C3A61B0C68BE9B0C|rigid:T0m2E1C2zxTMlkQol7HWsnYedN0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P54259	uniprotkb:A0A5P8YJG2	intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076.3|ensembl:ENSP00000379915.2	intact:EBI-2848562|uniprotkb:Q0WJA7|uniprotkb:Q7CGB3|uniprotkb:A0A384LQ43	psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym)	psi-mi:a0a5p8yjg2_yerpe(display_long)|uniprotkb:ftsZ(gene name)|psi-mi:ftsZ(display_short)|uniprotkb:sfiB(gene name synonym)|uniprotkb:sulB(gene name synonym)|uniprotkb:YPO0560(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848559|imex:IM-13779-5274	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000111676.15(gene)|ensembl:ENST00000356654.8(transcript)|ensembl:ENST00000396684.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001906""(cell killing)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007417""(central nervous system development)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008584""(male gonad development)|go:""GO:0009791""(post-embryonic development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016477""(cell migration)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030011""(maintenance of cell polarity)|go:""GO:0032094""(response to food)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0070161""(anchoring junction)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724|refseq:NP_001007027.1|refseq:NP_001931.2|dip:DIP-29423N|efo:""Orphanet:101""|panther:PTHR13859(orthology-group)"	"interpro:IPR000158(Cell division protein FtsZ, N-terminal)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR024757|interpro:IPR020805|interpro:IPR037103|refseq:WP_002210430.1|go:""GO:0000917""(division septum assembly)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|go:""GO:0051258""(protein polymerization)|go:""GO:0051301""(cell division)|interpro:IPR036525|refseq:YP_002345631.1|interpro:IPR045061|panther:PTHR30314(orthology-group)"	"psi-mi:""MI:0469""(intact)"	crc64:B47603486C672637	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606	rogid:dbTnqnEu5rzPEGlmOJdOOgz9e9s632	intact-crc:939DBA237C0FC0E2|rigid:51mvzY0u9/yCvVIOV7tfD7elwu0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HBK9	uniprotkb:A0A0H2W0Z5	intact:EBI-2838010|uniprotkb:Q5PZ02|uniprotkb:A6NP79|ensembl:ENSP00000358896.3|uniprotkb:Q0VDK3|uniprotkb:Q0VDK4	intact:EBI-2844986|uniprotkb:Q74Y40|uniprotkb:Q0WKG8|uniprotkb:Q7CFX1|uniprotkb:A0A380PIN3|uniprotkb:A0A384LBS1	"psi-mi:as3mt_human(display_long)|uniprotkb:AS3MT(gene name)|psi-mi:AS3MT(display_short)|uniprotkb:CYT19(gene name synonym)|uniprotkb:Methylarsonite methyltransferase(gene name synonym)|uniprotkb:""S-adenosyl-L-methionine:arsenic(III) methyltransferase""(gene name synonym)"	psi-mi:a0a0h2w0z5_yerpe(display_long)|uniprotkb:YPO0134(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848588|imex:IM-13779-5278	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_065733.2|ensembl:ENSG00000214435.9(gene)|ensembl:ENST00000369880.8(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0009404""(toxin metabolic process)|go:""GO:0018872""(arsonoacetate metabolic process)|go:""GO:0030791""(arsenite methyltransferase activity)|go:""GO:0032259""(methylation)|interpro:IPR025714|interpro:IPR026669|interpro:IPR029063|reactome:R-HSA-156581|panther:PTHR43675(orthology-group)"	"interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR023323|interpro:IPR023319|interpro:IPR018974|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR044146|refseq:WP_002208916.1|go:""GO:0003676""(nucleic acid binding)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|interpro:IPR055179|interpro:IPR032639|interpro:IPR037027|interpro:IPR041692|refseq:YP_002345220.1|interpro:IPR050437"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PyXYsSDP7u4vW94iaL8DLvKhVNA9606	rogid:ttlZGvCMP/bbGv1PpYdheTErKIk632	intact-crc:062C048ACC6F189C|rigid:5wBVPaTqBezNVb4Xi3ItXMC5ZOw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q68CP9	uniprotkb:Q0WJF8	intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044.6	intact:EBI-2840848|uniprotkb:Q74Q40|uniprotkb:A0A384KWW8|uniprotkb:A0A0H2W7R8|uniprotkb:Q7CG97	psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym)	psi-mi:q0wjf8_yerpe(display_long)|uniprotkb:YPO0507(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848595|imex:IM-13779-5276	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000189079.18(gene)|ensembl:ENST00000334344.11(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006337""(nucleosome disassembly)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|interpro:IPR003150(DNA-binding RFX)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0042592""(homeostatic process)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0048568""(embryonic organ development)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060982""(coronary artery morphogenesis)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|interpro:IPR052406|mint:Q68CP9|rcsb pdb:7VDV|rcsb pdb:7Y8R|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_001334768.1|refseq:NP_689854.2|dip:DIP-33391N|efo:""Orphanet:1465"""	interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|refseq:YP_002345580.1|refseq:WP_002210474.1|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)|interpro:IPR050708|panther:PTHR32305(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/17	rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606	rogid:JSZl/NaLilra6W552YbRdX1LvXc632	intact-crc:1CD65ADC1753F9C2|rigid:D+Vcc82aF81/HoYnd/DV/E0GwxI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YB53	uniprotkb:P18850	intact:EBI-2848580	intact:EBI-852157|uniprotkb:O15139|uniprotkb:Q5VW62|uniprotkb:Q6IPB5|uniprotkb:Q9UEC9|ensembl:ENSP00000356919.3|ensembl:ENSP00000505025.1|ensembl:ENSP00000505998.1	psi-mi:a0a5p8yb53_yerpe(display_long)|uniprotkb:YP_3258(locus name)|uniprotkb:y0439(locus name)	psi-mi:atf6a_human(display_long)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)|uniprotkb:ATF6(gene name)|psi-mi:ATF6(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848577|imex:IM-13779-5275	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3T4Z3(uniprot-removed-ac)|interpro:IPR004776(Auxin efflux carrier)|interpro:IPR038770|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|refseq:WP_002224020.1"	"panther:PTHR46164(orthology-group)|ensembl:ENSG00000118217.7(gene)|ensembl:ENST00000367942.4(transcript)|ensembl:ENST00000681738.1(transcript)|ensembl:ENST00000681801.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001654""(eye development)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006457""(protein folding)|go:""GO:0007165""(signal transduction)|go:""GO:0007601""(visual perception)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016020""(membrane)|go:""GO:0019899""(enzyme binding)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036500""(ATF6-mediated unfolded protein response)|go:""GO:0036503""(ERAD pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903893""(positive regulation of ATF6-mediated unfolded protein response)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR046347|interpro:IPR051882|mint:P18850|reactome:R-HSA-380994|reactome:R-HSA-381033|reactome:R-HSA-381183|refseq:NP_031374.2|dip:DIP-29304N|efo:""Orphanet:1872""|efo:""Orphanet:49382"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Ih9cj2DmTmrLdVNjz8JMsi2oTPk632	rogid:mIU7Apng6rQ423SQnZTsceVSRus9606	intact-crc:C4CB4B9F09367ACF|rigid:UlsnDloVI0tDdkVEI9JYkenO+Tw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95376	uniprotkb:Q0WC27	intact:EBI-711158|ensembl:ENSP00000348769.4|ensembl:ENSP00000403222.1|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9	intact:EBI-2848605|uniprotkb:Q74WZ6|uniprotkb:A0A3N4B5D0|uniprotkb:A0A0H2W3G7|uniprotkb:Q7CK75|uniprotkb:A0A384LD25	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)	psi-mi:q0wc27_yerpe(display_long)|uniprotkb:YPO3261(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848602|imex:IM-13779-5277	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000177479.20(gene)|ensembl:ENST00000356401.9(transcript)|ensembl:ENST00000449376.5(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0048588""(developmental cell growth)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0071425""(hematopoietic stem cell proliferation)|go:""GO:1903955""(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR031127|interpro:IPR044066|interpro:IPR045840|interpro:IPR047555|interpro:IPR047556|mint:O95376|rcsb pdb:7OD1|rcsb pdb:7ONI|reactome:R-HSA-983168|refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|refseq:XP_016861020.1|refseq:XP_016861021.1|panther:PTHR11685(orthology-group)"	"interpro:IPR000120(Amidase signature enzyme)|interpro:IPR023631|interpro:IPR014087(Amidohydrolase, AtzE type)|go:""GO:0003824""(catalytic activity)|interpro:IPR036928|refseq:WP_002208739.1|refseq:YP_002348161.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	rogid:NfYkFCZlGhb/Cj0s0hKCCKaJw0k632	intact-crc:124061D35E7D9B88|rigid:w2ZwvsgBreFdmKaCc0zJkWYM7gg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GZX8	uniprotkb:Q99941	intact:EBI-2843751|uniprotkb:Q74V95|uniprotkb:A0A0H2W3N0|uniprotkb:Q7CHR8|uniprotkb:Q0WGN7|uniprotkb:A0A384KT94	intact:EBI-2841031|uniprotkb:Q99637|uniprotkb:Q5SSW7|uniprotkb:Q13269|uniprotkb:Q9H3W1|uniprotkb:Q9NPL0|uniprotkb:Q99635|uniprotkb:Q14345|uniprotkb:Q9H3V9|uniprotkb:B0UYX6|uniprotkb:Q14343|ensembl:ENSP00000293709.6|ensembl:ENSP00000364349.3|ensembl:ENSP00000404725.2|ensembl:ENSP00000404814.2	psi-mi:a0a2u2gzx8_yerpe(display_long)|uniprotkb:YPO1535(locus name)	psi-mi:atf6b_human(display_long)|uniprotkb:ATF6B(gene name)|psi-mi:ATF6B(display_short)|uniprotkb:CREBL1(gene name synonym)|uniprotkb:G13(gene name synonym)|uniprotkb:Activating transcription factor 6 beta(gene name synonym)|uniprotkb:Protein G13(gene name synonym)|uniprotkb:cAMP response element-binding protein-related protein(gene name synonym)|uniprotkb:cAMP-responsive element-binding protein-like 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848570|imex:IM-13779-5279	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000522(Bacterial transport system permease protein)|refseq:WP_002211881.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR037294|refseq:YP_002346551.1"	"refseq:NP_001129625.1|refseq:NP_004372.3|ensembl:ENSG00000168468.12(gene)|ensembl:ENSG00000213676.13(gene)|ensembl:ENSG00000228628.8(gene)|ensembl:ENSG00000234539.9(gene)|ensembl:ENST00000293709.10(transcript)|ensembl:ENST00000375203.8(transcript)|ensembl:ENST00000425571.6(transcript)|ensembl:ENST00000427136.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007165""(signal transduction)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0036500""(ATF6-mediated unfolded protein response)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0090575""(RNA polymerase II transcription regulator complex)|go:""GO:1903892""(negative regulation of ATF6-mediated unfolded protein response)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR004827(""Basic-leucine zipper (bZIP) transcription factor"")|interpro:IPR046347|interpro:IPR051882|reactome:R-HSA-8874177|panther:PTHR46164(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l+psx95jXdNVBQMnKWDbWE5epic632	rogid:HEe34jikjdOE5qyUIfTFbAB5g3g9606	intact-crc:D37B592CE5E0C28E|rigid:SEvFm2u+K4xWOIT7Z67C/uS8I9I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P36406	uniprotkb:Q8D1P8	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524.9	intact:EBI-2841883	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:q8d1p8_yerpe(display_long)|uniprotkb:tcaA1(gene name)|psi-mi:tcaA1(display_short)|uniprotkb:y0183(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848614|imex:IM-13779-5280	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|ensembl:ENSG00000113595.15(gene)|ensembl:ENST00000231524.14(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0003924""(GTPase activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019003""(GDP binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR024156|interpro:IPR027370|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|refseq:XP_016864933.1|panther:PTHR11711(orthology-group)|ensembl:ENSP00000231524.9|ensembl:ENST00000274327.11|ensembl:ENSP00000274327.7|ensembl:ENST00000381018.7|ensembl:ENSP00000370406.3"	interpro:IPR018003	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:LfA2Lz71pTe9HDOA0UOS0/RgEsY632	intact-crc:FD90CB2FD5D06033|rigid:8GlMLYqwf2LRHlOjZMBUZTq482Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YES8	uniprotkb:Q96GX9	intact:EBI-2848652|uniprotkb:Q74US7|uniprotkb:A0A0H2W5A9|uniprotkb:Q7CHW1|uniprotkb:A0A384KDB2	intact:EBI-359248|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3|ensembl:ENSP00000379133.3	psi-mi:a0a5p8yes8_yerpe(display_long)|uniprotkb:sdaA(gene name)|psi-mi:sdaA(display_short)|uniprotkb:YPO1771(locus name)	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848649|imex:IM-13779-5281	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029009|interpro:IPR004644(Iron-sulphur-dependent L-serine dehydratase single chain form)|interpro:IPR005130(Serine dehydratase alpha chain)|interpro:IPR005131(Serine dehydratase beta chain)|refseq:WP_002211079.1|go:""GO:0003941""(L-serine ammonia-lyase activity)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:YP_002346768.1|interpro:IPR051318|panther:PTHR30182(orthology-group)"	"refseq:NP_057041.2|ensembl:ENSG00000149089.13(gene)|ensembl:ENST00000395787.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0019509""(L-methionine salvage from methylthioadenosine)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046570""(methylthioribulose 1-phosphate dehydratase activity)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|panther:PTHR10640(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yVnD/73Ksx+jEUDkJwTGNlx1tGM632	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	intact-crc:53ADBAC1FDB53B75|rigid:MZUXhlE4HqN2SiEnl0p9cZPQNRY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96GX9	uniprotkb:Q8D0V9	intact:EBI-359248|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3|ensembl:ENSP00000379133.3	intact:EBI-2848637|uniprotkb:Q74SK8	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	psi-mi:q8d0v9_yerpe(display_long)|uniprotkb:dmsC2(gene name)|psi-mi:dmsC2(display_short)|uniprotkb:YP_2592(locus name)|uniprotkb:y1517(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848642|imex:IM-13779-5283	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_057041.2|ensembl:ENSG00000149089.13(gene)|ensembl:ENST00000395787.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0019509""(L-methionine salvage from methylthioadenosine)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046570""(methylthioribulose 1-phosphate dehydratase activity)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|panther:PTHR10640(orthology-group)"	"interpro:IPR007059(""DMSO reductase anchor subunit (DmsC)"")|go:""GO:0016020""(membrane)|go:""GO:0019645""(anaerobic electron transport chain)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	rogid:/Lc0yyHu5XkosmBiRlvq26qrMIY632	intact-crc:2A56DA61C26F4E6B|rigid:sQ7NIiMYPu5fY3w7teQTR1utzOo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D162	uniprotkb:Q96GX9	intact:EBI-2846008|uniprotkb:Q74WU1	intact:EBI-359248|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3|ensembl:ENSP00000379133.3	psi-mi:q8d162_yerpe(display_long)|uniprotkb:YP_0743(locus name)|uniprotkb:secF(gene name)|psi-mi:secF(display_short)|uniprotkb:y0994(locus name)	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848630|imex:IM-13779-5282	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR022813|interpro:IPR022646|interpro:IPR022645|interpro:IPR005665(SecF protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0015450""(protein-transporting ATPase activity)|go:""GO:0043952""(protein transport by the Sec complex)|go:""GO:0065002""(intracellular protein transmembrane transport)|interpro:IPR048634"	"refseq:NP_057041.2|ensembl:ENSG00000149089.13(gene)|ensembl:ENST00000395787.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0019509""(L-methionine salvage from methylthioadenosine)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046570""(methylthioribulose 1-phosphate dehydratase activity)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|panther:PTHR10640(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:wwgl8NPr9GdWJzJ+d/9SFdQZog8632	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	intact-crc:DDCBAB61C07A8BA9|rigid:sPUoT8jIE4yjjQVIqVmEOmCmgSk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJJ5	uniprotkb:P20073	intact:EBI-2842956|uniprotkb:Q0WKJ3	intact:EBI-2338704|uniprotkb:Q5F2H3|uniprotkb:Q5T0M6|uniprotkb:Q5T0M7|ensembl:ENSP00000362010.4|intact:EBI-28973842	psi-mi:hslu_yerpe(display_long)|uniprotkb:hslU(gene name)|psi-mi:hslU(display_short)|uniprotkb:Unfoldase HslU(gene name synonym)|uniprotkb:YPO0105(locus name)|uniprotkb:y0294(locus name)|uniprotkb:YP_0107(locus name)	psi-mi:anxa7_human(display_long)|uniprotkb:ANXA7(gene name)|psi-mi:ANXA7(display_short)|uniprotkb:ANX7(gene name synonym)|uniprotkb:SNX(gene name synonym)|uniprotkb:Annexin-7(gene name synonym)|uniprotkb:Annexin VII(gene name synonym)|uniprotkb:Synexin(gene name synonym)|uniprotkb:OK/SW-cl.95(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848679|imex:IM-13779-5285	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR004491(Heat shock protein HslU)|interpro:IPR027417|go:""GO:0008233""(peptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0009376""(HslUV protease complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043335""(protein unfolding)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|refseq:WP_002208943.1|refseq:YP_002345195.1|interpro:IPR050052|panther:PTHR48102(orthology-group)"	"refseq:NP_001147.1|refseq:NP_004025.1|refseq:XP_016871651.1|refseq:XP_016871652.1|ensembl:ENSG00000138279.16(gene)|ensembl:ENST00000372919.8(transcript)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005544""(calcium-dependent phospholipid binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006914""(autophagy)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0012506""(vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0048306""(calcium-dependent protein binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P20073|rcsb pdb:8W5S|ensembl:ENSP00000362010.4|ensembl:ENST00000372921.10|ensembl:ENSP00000362012.4|panther:PTHR10502(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9NL3dzNGgq2JqZd7+stwnNgbDk0632	rogid:ad3I49rhRoZ0hG8ruDgSQWocVuw9606	intact-crc:B66A2734921E0433|rigid:/IhNYlACjqnY/VjDC2c40F60+Zg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GVV5	uniprotkb:O43747	intact:EBI-2848661|uniprotkb:Q0WGP6|uniprotkb:Q7CHR3|uniprotkb:A0A384LCC2	intact:EBI-447609|uniprotkb:O75709|uniprotkb:O75842|uniprotkb:Q9UG09|uniprotkb:Q9Y3U4|ensembl:ENSP00000299980.4|ensembl:ENSP00000454523.1	psi-mi:a0a2u2gvv5_yerpe(display_long)|uniprotkb:YPO1526(locus name)	psi-mi:ap1g1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit gamma-1(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin subunit gamma-1(gene name synonym)|uniprotkb:Gamma1-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 gamma-1 large chain(gene name synonym)|uniprotkb:AP1G1(gene name)|psi-mi:AP1G1(display_short)|uniprotkb:ADTG(gene name synonym)|uniprotkb:CLAPG1(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit gamma-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848665|imex:IM-13779-5284	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR032712|interpro:IPR007844(AsmA)|refseq:WP_002211874.1|go:""GO:0005886""(plasma membrane)|go:""GO:0090313""(regulation of protein targeting to membrane)|refseq:YP_002346542.1|interpro:IPR052894|panther:PTHR30441(orthology-group)"	"ensembl:ENSG00000166747.13(gene)|ensembl:ENST00000299980.9(transcript)|ensembl:ENST00000569748.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005518""(collagen binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0005905""(clathrin-coated pit)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006896""(Golgi to vacuole transport)|go:""GO:0016020""(membrane)|go:""GO:0016182""(synaptic vesicle budding from endosome)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019894""(kinesin binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0030665""(clathrin-coated vesicle membrane)|go:""GO:0030742""(GTP-dependent protein binding)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032438""(melanosome organization)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0035615""(clathrin adaptor activity)|go:""GO:0035646""(endosome to melanosome transport)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043323""(positive regulation of natural killer cell degranulation)|go:""GO:0045954""(positive regulation of natural killer cell mediated cytotoxicity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048488""(synaptic vesicle endocytosis)|go:""GO:0055037""(recycling endosome)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0090160""(Golgi to lysosome transport)|go:""GO:0098793""(presynapse)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017107(Adaptor protein complex AP-1, gamma subunit)|interpro:IPR050840|mint:O43747|rcsb pdb:1IU1|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001025178.1|refseq:NP_001119.3|efo:""Orphanet:528084""|panther:PTHR22780(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FFiHcUgeYNIDG2pyac5+94Afrxg632	rogid:E0niV91xZ1PV6Pr6Koq3Xs+9nKg9606	intact-crc:668CE43E42D3F8E6|rigid:hgFKwW+l1Wd8m4YTzFK9Lg6a1ik	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q12802	uniprotkb:Q65AD6	intact:EBI-1373806|uniprotkb:Q14572|uniprotkb:Q59FP6|uniprotkb:Q86W90|uniprotkb:Q8WXQ6|uniprotkb:Q96JP6|uniprotkb:Q96P79|uniprotkb:Q9Y5T0|uniprotkb:Q9Y5T6|ensembl:ENSP00000378026.3|intact:EBI-28978093	intact:EBI-2848693|uniprotkb:A0A5P8YLT6|uniprotkb:Q74YH0|uniprotkb:Q9ZGY8|uniprotkb:A0A384L333|uniprotkb:A0A1U8QSE1|uniprotkb:Q7ARB9|uniprotkb:A0A7Y8RJD1	psi-mi:akp13_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 13(gene name synonym)|uniprotkb:Breast cancer nuclear receptor-binding auxiliary protein(gene name synonym)|uniprotkb:Human thyroid-anchoring protein 31(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor Lbc(gene name synonym)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:Lymphoid blast crisis oncogene(gene name synonym)|uniprotkb:Non-oncogenic Rho GTPase-specific GTP exchange factor(gene name synonym)|uniprotkb:AKAP13(gene name)|psi-mi:AKAP13(display_short)|uniprotkb:BRX(gene name synonym)|uniprotkb:HT31(gene name synonym)|uniprotkb:LBC(gene name synonym)	psi-mi:q65ad6_yerpe(display_long)|uniprotkb:YPMT1.65(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848697|imex:IM-13779-5288	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006729.4|refseq:NP_009131.2|refseq:NP_001257475.1|ensembl:ENSG00000170776.22(gene)|ensembl:ENST00000394518.7(transcript)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007507""(heart development)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0046872""(metal ion binding)|go:""GO:0051018""(protein kinase A binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060297""(regulation of sarcomere organization)|go:""GO:0060348""(bone development)|go:""GO:0071875""(adrenergic receptor signaling pathway)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018459|interpro:IPR035899|interpro:IPR041020|interpro:IPR046349|interpro:IPR051632|mint:Q12802|rcsb pdb:2DRN|rcsb pdb:2LG1|rcsb pdb:4D0N|rcsb pdb:4D0O|rcsb pdb:6BCA|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|dip:DIP-180N|panther:PTHR13944(orthology-group)"	"refseq:NP_395410.1|refseq:YP_094013.1|refseq:WP_002228776.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pHHpKUh10J/O/fp06k4NaNhJF6U9606	rogid:vK6c2fswBxCB0KOWBKRoRxD8tt0632	intact-crc:72F3C430C9AD381E|rigid:4DMRxvsOEg6HDRDi1FDUi1ngGCY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q10567	uniprotkb:Q8D1R0	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000350199.2	intact:EBI-2843803	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:q8d1r0_yerpe(display_long)|uniprotkb:degQ(gene name)|psi-mi:degQ(display_short)|uniprotkb:y0137(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848672|imex:IM-13779-5286	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR11134(orthology-group)|dip:DIP-24207N|rcsb pdb:8D4F|rcsb pdb:8D4G|rcsb pdb:8D9R|rcsb pdb:8D9S|rcsb pdb:8D9T|rcsb pdb:8D9U|rcsb pdb:8D9V|rcsb pdb:8D9W|reactome:R-HSA-164940|reactome:R-HSA-2132295|ensembl:ENSG00000100280.17(gene)|ensembl:ENST00000357586.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001822""(kidney development)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007368""(determination of left/right symmetry)|go:""GO:0007507""(heart development)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060155""(platelet dense granule organization)|go:""GO:0110010""(basolateral protein secretion)|go:""GO:1903232""(melanosome assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:7R4H|rcsb pdb:7UX3|rcsb pdb:8D4C|rcsb pdb:8D4D|rcsb pdb:8D4E|reactome:R-HSA-432720|reactome:R-HSA-432722|refseq:NP_001118.3|refseq:NP_001159491.1|refseq:NP_663782.2|efo:""Orphanet:171851"""	"interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|interpro:IPR036034"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0rgLm5svAZPXNbtyKTFD/tyNZnI9606	rogid:AA9pxma2K+wssT66h3sgiRuf6Uc632	intact-crc:C825935F222E3367|rigid:zTYEVTS+K5xc65Q1prvs/tgvybs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CJF3	uniprotkb:P00352	intact:EBI-2846856|uniprotkb:Q74SI9	intact:EBI-752170|ensembl:ENSP00000297785.3|uniprotkb:O00768|uniprotkb:Q5SYR1	"psi-mi:dnlj_yerpe(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:""Polydeoxyribonucleotide synthase [NAD(+)]""(gene name synonym)|uniprotkb:YPO2989(locus name)|uniprotkb:YP_2614(locus name)|uniprotkb:y1492(locus name)"	psi-mi:al1a1_human(display_long)|uniprotkb:Aldehyde dehydrogenase family 1 member A1(gene name synonym)|uniprotkb:Aldehyde dehydrogenase, cytosolic(gene name synonym)|uniprotkb:ALHDII(gene name synonym)|uniprotkb:ALDH-E1(gene name synonym)|uniprotkb:ALDH1A1(gene name)|psi-mi:ALDH1A1(display_short)|uniprotkb:ALDC(gene name synonym)|uniprotkb:ALDH1(gene name synonym)|uniprotkb:PUMB1(gene name synonym)|uniprotkb:3-deoxyglucosone dehydrogenase(gene name synonym)|uniprotkb:Retinal dehydrogenase 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848686|imex:IM-13779-5287	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033136|interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR004149(Zinc-finger, NAD-dependent DNA ligase C4-type)|refseq:WP_002213368.1|go:""GO:0003677""(DNA binding)|go:""GO:0003911""(""DNA ligase (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006288""(obsolete base-excision repair, DNA ligation)|go:""GO:0046872""(metal ion binding)|interpro:IPR036420|interpro:IPR041663|refseq:YP_002347913.1|panther:PTHR23389(orthology-group)"	"ensembl:ENSG00000165092.13(gene)|ensembl:ENST00000297785.8(transcript)|go:""GO:0001523""(retinoid metabolic process)|go:""GO:0001758""(retinal dehydrogenase activity)|go:""GO:0004029""(""aldehyde dehydrogenase (NAD+) activity"")|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005497""(androgen binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006081""(aldehyde metabolic process)|go:""GO:0009449""(gamma-aminobutyric acid biosynthetic process)|go:""GO:0018479""(""benzaldehyde dehydrogenase (NAD+) activity"")|go:""GO:0019145""(""aminobutyraldehyde dehydrogenase (NAD+) activity"")|go:""GO:0030392""(fructosamine catabolic process)|go:""GO:0030424""(axon)|go:""GO:0036438""(maintenance of lens transparency)|go:""GO:0042572""(retinol metabolic process)|go:""GO:0045202""(synapse)|go:""GO:0051287""(NAD binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0106373""(3-deoxyglucosone dehydrogenase activity)|go:""GO:0110095""(cellular detoxification of aldehyde)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|rcsb pdb:4WB9|rcsb pdb:4WJ9|rcsb pdb:4WP7|rcsb pdb:4WPN|rcsb pdb:4X4L|rcsb pdb:5AC2|rcsb pdb:5L2M|rcsb pdb:5L2N|rcsb pdb:5L2O|rcsb pdb:5TEI|rcsb pdb:6DUM|rcsb pdb:7JWS|rcsb pdb:7JWT|rcsb pdb:7JWU|rcsb pdb:7JWV|rcsb pdb:7JWW|rcsb pdb:7UM9|rcsb pdb:8D46|rcsb pdb:8DNO|rcsb pdb:8ENE|rcsb pdb:8PVH|rcsb pdb:8T0N|rcsb pdb:8T0T|rcsb pdb:8WFQ|reactome:R-HSA-5365859|reactome:R-HSA-70350|reactome:R-HSA-71384|refseq:NP_000680.2|panther:PTHR11699(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ABzJi1jMOUD1WGHNwTu2zo0ozls632	rogid:59BsLsRErg8L8BRi/1Wp6ahycX09606	intact-crc:C20BD8398679DD9D|rigid:vu5PexJngJBCinTsm06qbyC6jsM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLU2	uniprotkb:P55196	intact:EBI-2848736	intact:EBI-365875|uniprotkb:O75089|uniprotkb:Q5TIG6|uniprotkb:O75087|uniprotkb:O75088|uniprotkb:Q9NSN7|uniprotkb:Q9NU92|uniprotkb:Q5TIG7|uniprotkb:Q59FP0|ensembl:ENSP00000404595.2	psi-mi:q8clu2_yerpe(display_long)|uniprotkb:y0226(locus name)	psi-mi:afad_human(display_long)|uniprotkb:AFDN(gene name)|psi-mi:AFDN(display_short)|uniprotkb:AF6(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 6 protein(gene name synonym)|uniprotkb:Afadin adherens junction formation factor(gene name synonym)|uniprotkb:MLLT4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848733|imex:IM-13779-5292	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"refseq:XP_005267053.1|rcsb pdb:5A6C|rcsb pdb:7QCR|refseq:NP_001035089.1|refseq:NP_001193937.1|refseq:NP_001278893.1|reactome:R-HSA-418990|ensembl:ENSG00000130396.22(gene)|ensembl:ENST00000447894.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016607""(nuclear speck)|go:""GO:0022409""(positive regulation of cell-cell adhesion)|go:""GO:0030054""(cell junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0044331""(cell-cell adhesion mediated by cadherin)|go:""GO:0045296""(cadherin binding)|go:""GO:0046930""(pore complex)|go:""GO:0046931""(pore complex assembly)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051015""(actin filament binding)|go:""GO:0061951""(establishment of protein localization to plasma membrane)|go:""GO:0070160""(tight junction)|go:""GO:0070830""(bicellular tight junction assembly)|go:""GO:0090557""(establishment of endothelial intestinal barrier)|go:""GO:2000049""(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR028842|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977|mint:P55196|rcsb pdb:1T2M|rcsb pdb:1XZ9|rcsb pdb:2AIN|rcsb pdb:2EXG|panther:PTHR10398(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5HyUa7JBgXp2+pRD7HwFGE0KIds632	rogid:x7kK5K1+wAFZFdVopvQ/l496J5U9606	intact-crc:1F446444321A5989|rigid:THS2qwS8NXU207NU3BqEjrVBW9w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08117	uniprotkb:A0A2U2H129	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	intact:EBI-2842176|uniprotkb:Q7ARE9|uniprotkb:A0A1U8QLB5|uniprotkb:O68740|uniprotkb:A0A384K8I4	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:a0a2u2h129_yerpe(display_long)|uniprotkb:YPMT1.23c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848750|imex:IM-13779-5291	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	refseq:NP_395359.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:4xa0lQiscvHi6CWXCiIT959GpQw632	intact-crc:2A7850E3FF32DD91|rigid:e5G0nVNYNKIhnDRkMkLGx8koFeU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ79	uniprotkb:Q6ULP2	intact:EBI-2848724|uniprotkb:Q0WK65	intact:EBI-2848714|uniprotkb:Q9HAB9|uniprotkb:Q86VW3|uniprotkb:Q9NXS4|uniprotkb:Q8TCF3|uniprotkb:Q9H7E3|uniprotkb:Q6ZM66|uniprotkb:D6W5E9|intact:EBI-10988158|intact:EBI-28972107|ensembl:ENSP00000387071.1	psi-mi:def_yerpe(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:Polypeptide deformylase(gene name synonym)|uniprotkb:YPO0242(locus name)|uniprotkb:y4023(locus name)|uniprotkb:YP_0240(locus name)	psi-mi:aftin_human(display_long)|uniprotkb:AFTPH(gene name)|psi-mi:AFTPH(display_short)|uniprotkb:AFTH(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848711|imex:IM-13779-5289	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023635|refseq:WP_002209021.1|go:""GO:0006412""(translation)|go:""GO:0042586""(peptide deformylase activity)|go:""GO:0043686""(co-translational protein modification)|go:""GO:0046872""(metal ion binding)|interpro:IPR036821|refseq:YP_002345323.1|panther:PTHR10458(orthology-group)"	"refseq:XP_005264437.1|refseq:NP_001002243.1|refseq:NP_060127.3|refseq:NP_982261.2|ensembl:ENSG00000119844.17(gene)|ensembl:ENST00000409933.6(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0015031""(protein transport)|go:""GO:0030121""(AP-1 adaptor complex)|go:""GO:0030276""(clathrin binding)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046907""(intracellular transport)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR029205|interpro:IPR046359|mint:Q6ULP2|panther:PTHR16156(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0gMsJg2ASyOuH6uV9yRb1d4bMGk632	rogid:g/Z0njIYzzLZeiidOKVtPRUKnso9606	intact-crc:E070971D1EC4B300|rigid:jG+dpVHPIXqi485RoPKpChWHg8U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q08117	uniprotkb:A0A5P8YKN2	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|ensembl:ENSP00000317537.4|uniprotkb:B2RBL0|uniprotkb:Q14CJ1	intact:EBI-2847624|uniprotkb:A0A454XQW4|uniprotkb:Q74Y22|uniprotkb:A0A0H2W076|uniprotkb:Q7CFW2|uniprotkb:A0A384KWQ4	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:a0a5p8ykn2_yerpe(display_long)|uniprotkb:nirC(gene name)|psi-mi:nirC(display_short)|uniprotkb:YPO0159(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848743|imex:IM-13779-5290	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001121.2|ensembl:ENSG00000104964.15(gene)|ensembl:ENST00000327141.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001501""(skeletal system development)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0032091""(negative regulation of protein binding)|go:""GO:0040008""(regulation of growth)|go:""GO:0042802""(identical protein binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0060761""(negative regulation of response to cytokine stimulus)|go:""GO:0070555""(response to interleukin-1)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:2000210""(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|refseq:NP_945320.1|refseq:NP_945321.1"	"interpro:IPR000292(Formate/nitrite transporter)|interpro:IPR024002|interpro:IPR023271|refseq:WP_002208888.1|go:""GO:0016020""(membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:YP_002345245.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:IpEg8q11W6MKVP0GPHg3tEvv01o632	intact-crc:1F250E51C0CD6D3C|rigid:9o0AgCU1rik8RlwnW/NvzzWuuV0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZR5	uniprotkb:Q12802	intact:EBI-2839873	intact:EBI-1373806|uniprotkb:Q14572|uniprotkb:Q59FP6|uniprotkb:Q86W90|uniprotkb:Q8WXQ6|uniprotkb:Q96JP6|uniprotkb:Q96P79|uniprotkb:Q9Y5T0|uniprotkb:Q9Y5T6|ensembl:ENSP00000378026.3|intact:EBI-28978093	psi-mi:q8czr5_yerpe(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:y3537(locus name)	psi-mi:akp13_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 13(gene name synonym)|uniprotkb:Breast cancer nuclear receptor-binding auxiliary protein(gene name synonym)|uniprotkb:Human thyroid-anchoring protein 31(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor Lbc(gene name synonym)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:Lymphoid blast crisis oncogene(gene name synonym)|uniprotkb:Non-oncogenic Rho GTPase-specific GTP exchange factor(gene name synonym)|uniprotkb:AKAP13(gene name)|psi-mi:AKAP13(display_short)|uniprotkb:BRX(gene name synonym)|uniprotkb:HT31(gene name synonym)|uniprotkb:LBC(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848704|imex:IM-13779-5293	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028630|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016987""(sigma factor activity)|interpro:IPR042189|interpro:IPR036388|interpro:IPR050239"	"refseq:NP_006729.4|refseq:NP_009131.2|refseq:NP_001257475.1|ensembl:ENSG00000170776.22(gene)|ensembl:ENST00000394518.7(transcript)|go:""GO:0005078""(MAP-kinase scaffold activity)|go:""GO:0005085""(guanyl-nucleotide exchange factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005938""(cell cortex)|go:""GO:0007186""(G protein-coupled receptor signaling pathway)|go:""GO:0007507""(heart development)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035023""(regulation of Rho protein signal transduction)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0046872""(metal ion binding)|go:""GO:0051018""(protein kinase A binding)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0060297""(regulation of sarcomere organization)|go:""GO:0060348""(bone development)|go:""GO:0071875""(adrenergic receptor signaling pathway)|interpro:IPR000219(""Dbl homology (DH) domain"")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018459|interpro:IPR035899|interpro:IPR041020|interpro:IPR046349|interpro:IPR051632|mint:Q12802|rcsb pdb:2DRN|rcsb pdb:2LG1|rcsb pdb:4D0N|rcsb pdb:4D0O|rcsb pdb:6BCA|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|dip:DIP-180N|panther:PTHR13944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8NwL0C9CZc1yJ2fOOz9gZqJHCMI632	rogid:pHHpKUh10J/O/fp06k4NaNhJF6U9606	intact-crc:42AAEF62674C3BBF|rigid:0GgxXktX0bTjwiRuXFp4e8UJzmM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CHW4	uniprotkb:Q9NR19	intact:EBI-2848778|uniprotkb:Q74UT0	intact:EBI-372879|uniprotkb:A6NE90|uniprotkb:Q5QPH3|uniprotkb:Q8N238|uniprotkb:Q5QPH2|uniprotkb:Q96EL0|uniprotkb:Q9NQP7|uniprotkb:Q9UJ15|ensembl:ENSP00000353804.2	psi-mi:purt_yerpe(display_long)|uniprotkb:purT(gene name)|psi-mi:purT(display_short)|uniprotkb:5'-phosphoribosylglycinamide transformylase 2(gene name synonym)|uniprotkb:Formate-dependent GAR transformylase(gene name synonym)|uniprotkb:GAR transformylase 2(gene name synonym)|uniprotkb:Non-folate glycinamide ribonucleotide transformylase(gene name synonym)|uniprotkb:Phosphoribosylglycinamide formyltransferase 2(gene name synonym)|uniprotkb:YPO1775(locus name)|uniprotkb:YP_1618(locus name)|uniprotkb:y2533(locus name)	psi-mi:acsa_human(display_long)|uniprotkb:ACSS2(gene name)|psi-mi:ACSS2(display_short)|uniprotkb:Acetate--CoA ligase(gene name synonym)|uniprotkb:Acyl-activating enzyme(gene name synonym)|uniprotkb:Acetyl-CoA synthetase(gene name synonym)|uniprotkb:Acyl-CoA synthetase short-chain family member 2(gene name synonym)|uniprotkb:ACAS2(gene name synonym)|uniprotkb:Acetyl-CoA synthetase 1(gene name synonym)|uniprotkb:Propionate--CoA ligase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848783|imex:IM-13779-5296	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR003135(ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR005862(Phosphoribosylglycinamide formyltransferase 2)|interpro:IPR011054(Rudiment single hybrid motif)|refseq:WP_002211083.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004644""(phosphoribosylglycinamide formyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0043815""(phosphoribosylglycinamide formyltransferase 2 activity)|interpro:IPR048740|interpro:IPR054350|refseq:YP_002346772.1|panther:PTHR43055(orthology-group)"	"ensembl:ENSG00000131069.20(gene)|ensembl:ENST00000360596.7(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003987""(acetate-CoA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005829""(cytosol)|go:""GO:0006068""(ethanol catabolic process)|go:""GO:0006085""(acetyl-CoA biosynthetic process)|go:""GO:0007616""(long-term memory)|go:""GO:0008610""(lipid biosynthetic process)|go:""GO:0016208""(AMP binding)|go:""GO:0019413""(acetate biosynthetic process)|go:""GO:0019427""(acetyl-CoA biosynthetic process from acetate)|go:""GO:0019542""(propionate biosynthetic process)|go:""GO:0050218""(propionate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011904(Acetate--CoA ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR032387|interpro:IPR042099|interpro:IPR045851|reactome:R-HSA-2151201|reactome:R-HSA-71384|refseq:NP_001070020.2|refseq:NP_061147.1|panther:PTHR24095(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bCau0DjK5zfXGn3uk1MMfw6Caso632	rogid:n+4C7f+B/xE/yebr45s65+/s4t89606	intact-crc:FAA558EA4ACA9C02|rigid:Aj4eZ2pbwjqlMqzVmAdCOfut6/0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CH75	uniprotkb:Q9BR61	intact:EBI-2848797|uniprotkb:Q74WB6	intact:EBI-2848793|intact:EBI-5774335|ensembl:ENSP00000356567.3|ensembl:ENSP00000495710.1	psi-mi:q7ch75_yerpe(display_long)|uniprotkb:dld(gene name)|psi-mi:dld(display_short)|uniprotkb:D-lactate dehydrogenase(gene name synonym)|uniprotkb:YPO1177(locus name)	psi-mi:acbd6_human(display_long)|uniprotkb:ACBD6(gene name)|psi-mi:ACBD6(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848790|imex:IM-13779-5298	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016172(D-lactate dehydrogenase, C-terminal subdomain 1)|interpro:IPR016173(D-lactate dehydrogenase, C-terminal subdomain 2)|interpro:IPR012256(D-lactate dehydrogenase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR015409(D-lactate dehydrogenase, membrane binding, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|go:""GO:0006089""(lactate metabolic process)|go:""GO:0022904""(respiratory electron transport chain)|go:""GO:0031234""(extrinsic component of cytoplasmic side of plasma membrane)|go:""GO:0048038""(quinone binding)|go:""GO:0055085""(transmembrane transport)|go:""GO:0071949""(FAD binding)|go:""GO:0102029""(""D-lactate dehydrogenase (quinone) activity"")|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318|refseq:YP_002346215.1|interpro:IPR051264|panther:PTHR43716(orthology-group)"	"refseq:NP_115736.1|ensembl:ENSG00000230124.8(gene)|ensembl:ENST00000367595.4(transcript)|ensembl:ENST00000642319.1(transcript)|go:""GO:0000062""(fatty-acyl-CoA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008289""(lipid binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR002110(Ankyrin)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR035984|interpro:IPR036770|rcsb pdb:2COP|reactome:R-HSA-77289|panther:PTHR24119(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:emZYZa7owfNjrhtI5G/i7aHxGx8632	rogid:/AiN5BNIE0nDYr7xyVP8tdwSSSg9606	intact-crc:097F3B0A815B1E31|rigid:to4YwN82xjp0PHyTgLw/LOkOF9o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P60709	uniprotkb:A0A2S9PFE9	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|ensembl:ENSP00000494269.1|ensembl:ENSP00000494750.1|ensembl:ENSP00000495995.2|ensembl:ENSP00000501862.1|ensembl:ENSP00000502821.1|uniprotkb:Q96HG5	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848771|imex:IM-13779-5295	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:673556""|efo:""Orphanet:674653""|ensembl:ENSG00000075624.17(gene)|ensembl:ENST00000493945.6(transcript)|ensembl:ENST00000642480.2(transcript)|ensembl:ENST00000646664.1(transcript)|ensembl:ENST00000674681.1(transcript)|ensembl:ENST00000675515.1(transcript)|go:""GO:0000079""(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:""GO:0000776""(kinetochore)|go:""GO:0000785""(chromatin)|go:""GO:0000786""(nucleosome)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007163""(establishment or maintenance of cell polarity)|go:""GO:0007409""(axonogenesis)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016020""(membrane)|go:""GO:0016363""(nuclear matrix)|go:""GO:0016514""(SWI/SNF complex)|go:""GO:0016586""(RSC-type complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0019894""(kinesin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0021762""(substantia nigra development)|go:""GO:0022898""(regulation of transmembrane transporter activity)|go:""GO:0030027""(lamellipodium)|go:""GO:0030071""(regulation of mitotic metaphase/anaphase transition)|go:""GO:0030424""(axon)|go:""GO:0030863""(cortical cytoskeleton)|go:""GO:0030957""(Tat protein binding)|go:""GO:0031982""(vesicle)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0035060""(brahma complex)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0036464""(cytoplasmic ribonucleoprotein granule)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045176""(apical protein localization)|go:""GO:0045202""(synapse)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045597""(positive regulation of cell differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0048156""(tau protein binding)|go:""GO:0048870""(cell motility)|go:""GO:0050998""(nitric-oxide synthase binding)|go:""GO:0051621""(regulation of norepinephrine uptake)|go:""GO:0051623""(positive regulation of norepinephrine uptake)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070160""(tight junction)|go:""GO:0070316""(regulation of G0 to G1 transition)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071564""(npBAF complex)|go:""GO:0071565""(nBAF complex)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0072562""(blood microparticle)|go:""GO:0072749""(cellular response to cytochalasin B)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098871""(postsynaptic actin cytoskeleton)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140092""(bBAF complex)|go:""GO:0140288""(GBAF complex)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902459""(positive regulation of stem cell population maintenance)|go:""GO:1903076""(regulation of protein localization to plasma membrane)|go:""GO:1905168""(positive regulation of double-strand break repair via homologous recombination)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000045""(regulation of G1/S transition of mitotic cell cycle)|go:""GO:2000779""(regulation of double-strand break repair)|go:""GO:2000781""(positive regulation of double-strand break repair)|go:""GO:2000819""(regulation of nucleotide-excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|rcsb pdb:7P1H|rcsb pdb:7QJ6|rcsb pdb:7QJ9|rcsb pdb:7VDV|rcsb pdb:7W28|rcsb pdb:7W29|rcsb pdb:7Y8R|rcsb pdb:7ZTC|rcsb pdb:7ZTD|rcsb pdb:8COG|rcsb pdb:8DNH|rcsb pdb:8IB8|rcsb pdb:8OI8|rcsb pdb:8OID|rcsb pdb:8QR1|rcsb pdb:8RTT|rcsb pdb:8RTY|rcsb pdb:8RU2|rcsb pdb:8VRD|rcsb pdb:8VRJ|rcsb pdb:8VRK|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|rcsb pdb:8XVT|rcsb pdb:9C57|rcsb pdb:9C62|rcsb pdb:9C6N|rcsb pdb:9FJM|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-9824585|reactome:R-HSA-983231|reactome:R-HSA-9845323|refseq:NP_001092.1|efo:""Orphanet:2995""|efo:""Orphanet:64755""|efo:""Orphanet:79107""|dip:DIP-29686N|panther:PTHR11937(orthology-group)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	intact-crc:FE6CDFD1FCC5E7AF|rigid:ZjNCedpBeMafEnMG3A1eCRZ0Cwk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63261	uniprotkb:A0A380PMV7	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000458162.1|ensembl:ENSP00000458435.1|ensembl:ENSP00000459119.2|ensembl:ENSP00000459124.1|ensembl:ENSP00000460464.2|ensembl:ENSP00000460660.2|ensembl:ENSP00000461672.1|ensembl:ENSP00000466346.2|ensembl:ENSP00000477968.1|ensembl:ENSP00000505060.1|ensembl:ENSP00000505193.1|ensembl:ENSP00000505235.1|ensembl:ENSP00000506126.1|ensembl:ENSP00000506201.1|ensembl:ENSP00000506253.1|ensembl:ENSP00000516869.1|ensembl:ENSP00000516870.1|ensembl:ENSP00000516871.1|ensembl:ENSP00000516872.1|ensembl:ENSP00000516873.1|ensembl:ENSP00000516874.1|ensembl:ENSP00000516875.1|ensembl:ENSP00000516876.1|ensembl:ENSP00000516877.1|ensembl:ENSP00000516879.1|ensembl:ENSP00000516881.1|ensembl:ENSP00000516882.1|ensembl:ENSP00000516884.1|ensembl:ENSP00000516886.1|ensembl:ENSP00000516887.1	intact:EBI-2844891|uniprotkb:Q0WHD0|uniprotkb:Q7CHD7	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:a0a380pmv7_yerpe(display_long)|uniprotkb:YPO1280(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848757|imex:IM-13779-5294	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2995""|efo:""Orphanet:90635""|efo:""Orphanet:98942""|efo:""Orphanet:98944""|ensembl:ENSG00000184009.13(gene)|ensembl:ENSG00000291420.1(gene)|ensembl:ENST00000570382.2(transcript)|ensembl:ENST00000571721.6(transcript)|ensembl:ENST00000573283.7(transcript)|ensembl:ENST00000575087.5(transcript)|ensembl:ENST00000575659.6(transcript)|ensembl:ENST00000575842.5(transcript)|ensembl:ENST00000575994.6(transcript)|ensembl:ENST00000576544.6(transcript)|ensembl:ENST00000615544.5(transcript)|ensembl:ENST00000679480.1(transcript)|ensembl:ENST00000679778.1(transcript)|ensembl:ENST00000680227.1(transcript)|ensembl:ENST00000680727.1(transcript)|ensembl:ENST00000681052.1(transcript)|ensembl:ENST00000681842.1(transcript)|ensembl:ENST00000707466.1(transcript)|ensembl:ENST00000707467.1(transcript)|ensembl:ENST00000707468.1(transcript)|ensembl:ENST00000707469.1(transcript)|ensembl:ENST00000707470.1(transcript)|ensembl:ENST00000707471.1(transcript)|ensembl:ENST00000707472.1(transcript)|ensembl:ENST00000707473.1(transcript)|ensembl:ENST00000707474.1(transcript)|ensembl:ENST00000707479.1(transcript)|ensembl:ENST00000707482.1(transcript)|ensembl:ENST00000707485.1(transcript)|ensembl:ENST00000707487.1(transcript)|ensembl:ENST00000707489.1(transcript)|ensembl:ENST00000707490.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005522""(profilin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007409""(axonogenesis)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030016""(myofibril)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031941""(filamentous actin)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048870""(cell motility)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0120192""(tight junction assembly)|go:""GO:0120220""(basal body patch)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902396""(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7NVM|rcsb pdb:8DNF|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|refseq:NP_001186883.1|refseq:NP_001605.1|panther:PTHR11937(orthology-group)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR000669(Mannitol dehydrogenase, core)|interpro:IPR013118(Mannitol dehydrogenase, C-terminal)|interpro:IPR013131(Mannitol dehydrogenase, N-terminal)|interpro:IPR023027|refseq:WP_002208815.1|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0019594""(mannitol metabolic process)|interpro:IPR036291|refseq:YP_002346308.1|interpro:IPR050988|panther:PTHR43362(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:ULbk9Ouc3Zm8/01+99ckG1DmRQM632	intact-crc:BF70D48A3386BF1E|rigid:8ymhA9/iwaz4EWt9+VnrYcw6grk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63261	uniprotkb:Q7ARD3	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000458162.1|ensembl:ENSP00000458435.1|ensembl:ENSP00000459119.2|ensembl:ENSP00000459124.1|ensembl:ENSP00000460464.2|ensembl:ENSP00000460660.2|ensembl:ENSP00000461672.1|ensembl:ENSP00000466346.2|ensembl:ENSP00000477968.1|ensembl:ENSP00000505060.1|ensembl:ENSP00000505193.1|ensembl:ENSP00000505235.1|ensembl:ENSP00000506126.1|ensembl:ENSP00000506201.1|ensembl:ENSP00000506253.1|ensembl:ENSP00000516869.1|ensembl:ENSP00000516870.1|ensembl:ENSP00000516871.1|ensembl:ENSP00000516872.1|ensembl:ENSP00000516873.1|ensembl:ENSP00000516874.1|ensembl:ENSP00000516875.1|ensembl:ENSP00000516876.1|ensembl:ENSP00000516877.1|ensembl:ENSP00000516879.1|ensembl:ENSP00000516881.1|ensembl:ENSP00000516882.1|ensembl:ENSP00000516884.1|ensembl:ENSP00000516886.1|ensembl:ENSP00000516887.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848764|imex:IM-13779-5297	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:2995""|efo:""Orphanet:90635""|efo:""Orphanet:98942""|efo:""Orphanet:98944""|ensembl:ENSG00000184009.13(gene)|ensembl:ENSG00000291420.1(gene)|ensembl:ENST00000570382.2(transcript)|ensembl:ENST00000571721.6(transcript)|ensembl:ENST00000573283.7(transcript)|ensembl:ENST00000575087.5(transcript)|ensembl:ENST00000575659.6(transcript)|ensembl:ENST00000575842.5(transcript)|ensembl:ENST00000575994.6(transcript)|ensembl:ENST00000576544.6(transcript)|ensembl:ENST00000615544.5(transcript)|ensembl:ENST00000679480.1(transcript)|ensembl:ENST00000679778.1(transcript)|ensembl:ENST00000680227.1(transcript)|ensembl:ENST00000680727.1(transcript)|ensembl:ENST00000681052.1(transcript)|ensembl:ENST00000681842.1(transcript)|ensembl:ENST00000707466.1(transcript)|ensembl:ENST00000707467.1(transcript)|ensembl:ENST00000707468.1(transcript)|ensembl:ENST00000707469.1(transcript)|ensembl:ENST00000707470.1(transcript)|ensembl:ENST00000707471.1(transcript)|ensembl:ENST00000707472.1(transcript)|ensembl:ENST00000707473.1(transcript)|ensembl:ENST00000707474.1(transcript)|ensembl:ENST00000707479.1(transcript)|ensembl:ENST00000707482.1(transcript)|ensembl:ENST00000707485.1(transcript)|ensembl:ENST00000707487.1(transcript)|ensembl:ENST00000707489.1(transcript)|ensembl:ENST00000707490.1(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001738""(morphogenesis of a polarized epithelium)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005522""(profilin binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005884""(actin filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007409""(axonogenesis)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0016787""(hydrolase activity)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030016""(myofibril)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031941""(filamentous actin)|go:""GO:0035267""(NuA4 histone acetyltransferase complex)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042802""(identical protein binding)|go:""GO:0043296""(apical junction complex)|go:""GO:0044305""(calyx of Held)|go:""GO:0045202""(synapse)|go:""GO:0045214""(sarcomere organization)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0048870""(cell motility)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0072562""(blood microparticle)|go:""GO:0090303""(positive regulation of wound healing)|go:""GO:0097433""(dense body)|go:""GO:0098685""(Schaffer collateral - CA1 synapse)|go:""GO:0098973""(structural constituent of postsynaptic actin cytoskeleton)|go:""GO:0120192""(tight junction assembly)|go:""GO:0120220""(basal body patch)|go:""GO:0150111""(regulation of transepithelial transport)|go:""GO:1900242""(regulation of synaptic vesicle endocytosis)|go:""GO:1902396""(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7NVM|rcsb pdb:8DNF|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|refseq:NP_001186883.1|refseq:NP_001605.1|panther:PTHR11937(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:784D1871D0AD8B5A|rigid:gkijSd9mIhLj5MaJwKOVWgN7EEc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92685	uniprotkb:Q8ZBL9	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793.3	intact:EBI-2848809|uniprotkb:Q0WBQ7	"psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:""Dol-P-Man-dependent alpha(1-3)-mannosyltransferase""(gene name synonym)|uniprotkb:""Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase""(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)"	psi-mi:gsa_yerpe(display_long)|uniprotkb:hemL(gene name)|psi-mi:hemL(display_short)|uniprotkb:Glutamate-1-semialdehyde aminotransferase(gene name synonym)|uniprotkb:YPO3389(locus name)|uniprotkb:y0799(locus name)|uniprotkb:YP_0296(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848806|imex:IM-13779-5301	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000214160.10(gene)|ensembl:ENST00000397676.8(transcript)|go:""GO:0000033""(alpha-1,3-mannosyltransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0006488""(dolichol-linked oligosaccharide biosynthetic process)|go:""GO:0052925""(""dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"")|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR007873(ALG3)|mint:Q92685|reactome:R-HSA-446193|reactome:R-HSA-4720475|refseq:NP_001006942.1|refseq:NP_005778.1|efo:""Orphanet:79321""|panther:PTHR12646(orthology-group)"	"interpro:IPR004639(Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|rcsb pdb:4E77|refseq:WP_002209362.1|go:""GO:0005737""(cytoplasm)|go:""GO:0006782""(protoporphyrinogen IX biosynthetic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0042286""(glutamate-1-semialdehyde 2,1-aminomutase activity)|refseq:YP_002348281.1|interpro:IPR049704|panther:PTHR43713(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rogid:8/zU0ckO6UHPhe97Hffh90KgRjA632	intact-crc:34CD09B79A411FA2|rigid:VFuP54dlxDIKYQbQvbCsmlayjxc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A4D1V7	uniprotkb:A0A0H2W496	intact:EBI-2848824	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	psi-mi:a4d1v7_human(display_long)|uniprotkb:LOC402483(gene name)|psi-mi:LOC402483(display_short)|uniprotkb:tcag7.907(orf name)	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848821|imex:IM-13779-5299	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	-	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bvP1t1KF1YxCh6D6HZZfNxcE9RQ9606	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	intact-crc:CDC4179DA4517AE9|rigid:zfmis0QajmNH/5ap8ACVnsz6N+Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3V073	uniprotkb:Q9UGV2	intact:EBI-2848832	intact:EBI-2848835|uniprotkb:Q9H3N7|uniprotkb:Q96SM2|uniprotkb:Q9H8J6|uniprotkb:Q9H411|uniprotkb:Q9BXY7|uniprotkb:Q96PL8|uniprotkb:Q5TH32|uniprotkb:A2A2S8|uniprotkb:E1P5U7|uniprotkb:E1P5U8|ensembl:ENSP00000345292.1	psi-mi:a0a6b3v073_yerpe(display_long)|uniprotkb:y0859(locus name)	psi-mi:ndrg3_human(display_long)|uniprotkb:NDRG3(gene name)|psi-mi:NDRG3(display_short)|uniprotkb:N-myc downstream-regulated gene 3 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848847|imex:IM-13779-5300	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"uniprotkb:A0A6B3SZJ3(uniprot-removed-ac)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR050107|refseq:WP_002223226.1"	"refseq:NP_071922.2|refseq:NP_114402.1|ensembl:ENSG00000101079.21(gene)|ensembl:ENST00000349004.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0007165""(signal transduction)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030154""(cell differentiation)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0070062""(extracellular exosome)|interpro:IPR004142(Ndr)|interpro:IPR029058|mint:Q9UGV2|rcsb pdb:6L4B|rcsb pdb:6L4G|rcsb pdb:6L4H|refseq:XP_016883468.1|panther:PTHR11034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gbuCcuxKRXbgvu4tZlurt/LtiPs632	rogid:LT/4wll6MweX5LpCWTkUt0r8lQQ9606	intact-crc:B1258F66E7A585DB|rigid:uiMwd0F+KJK4JsC4RYQcfK82sEs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IZ83	uniprotkb:Q9RIC3	intact:EBI-1044483|uniprotkb:C9JBH6|uniprotkb:Q86YF0|uniprotkb:Q8IYL4|uniprotkb:Q8TEI8|uniprotkb:B4DLQ1|ensembl:ENSP00000293350.3	intact:EBI-56885267|uniprotkb:Q7BTT1	psi-mi:a16a1_human(display_long)|uniprotkb:ALDH16A1(gene name)|psi-mi:ALDH16A1(display_short)	psi-mi:q9ric3_yerpe(display_long)|uniprotkb:ymt(gene name)|psi-mi:ymt(display_short)|uniprotkb:tox(gene name synonym)|uniprotkb:YPMT1.74(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848854|imex:IM-13779-5302	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_699160.2|refseq:NP_001138868.1|ensembl:ENSG00000161618.10(gene)|ensembl:ENST00000293350.9(transcript)|go:""GO:0016020""(membrane)|go:""GO:0016620""(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q8IZ83|panther:PTHR11699(orthology-group)"	"refseq:NP_395420.2|refseq:NP_857705.3|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|go:""GO:0008808""(cardiolipin synthase activity)|go:""GO:0016020""(membrane)|go:""GO:0032049""(cardiolipin biosynthetic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BoCNAGkgDh2oJaclyaoXr117+iw9606	rogid:/8mxO/sUbVPkh1AMeB0FLnlkNWY632	intact-crc:B4EC708B612AEE9F|rigid:nh6SA4OgfsGrSzzDA0HoKhwWk9U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01903	uniprotkb:Q8CL89	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608.2|ensembl:ENSP00000372746.2|ensembl:ENSP00000378786.2|ensembl:ENSP00000402951.2|ensembl:ENSP00000404533.2|ensembl:ENSP00000405295.2|ensembl:ENSP00000410443.2|ensembl:ENSP00000479287.1	intact:EBI-2839866	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	psi-mi:q8cl89_yerpe(display_long)|uniprotkb:y1833(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848865|imex:IM-13779-5306	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-6063N|efo:""Orphanet:505""|ensembl:ENSG00000204287.14(gene)|ensembl:ENSG00000206308.11(gene)|ensembl:ENSG00000226260.9(gene)|ensembl:ENSG00000227993.9(gene)|ensembl:ENSG00000228987.9(gene)|ensembl:ENSG00000230726.9(gene)|ensembl:ENSG00000234794.9(gene)|ensembl:ENSG00000277263.1(gene)|ensembl:ENST00000383127.6(transcript)|ensembl:ENST00000383259.6(transcript)|ensembl:ENST00000395388.7(transcript)|ensembl:ENST00000411524.6(transcript)|ensembl:ENST00000414698.6(transcript)|ensembl:ENST00000416883.6(transcript)|ensembl:ENST00000442960.6(transcript)|ensembl:ENST00000613328.1(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001772""(immunological synapse)|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002469""(myeloid dendritic cell antigen processing and presentation)|go:""GO:0002491""(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:""GO:0002503""(peptide antigen assembly with MHC class II protein complex)|go:""GO:0002504""(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0009986""(cell surface)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0019886""(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:""GO:0023026""(MHC class II protein complex binding)|go:""GO:0030247""(polysaccharide binding)|go:""GO:0030658""(transport vesicle membrane)|go:""GO:0030666""(endocytic vesicle membrane)|go:""GO:0030669""(clathrin-coated endocytic vesicle membrane)|go:""GO:0031901""(early endosome membrane)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032395""(MHC class II receptor activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0032831""(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042608""(T cell receptor binding)|go:""GO:0042613""(MHC class II protein complex)|go:""GO:0043382""(positive regulation of memory T cell differentiation)|go:""GO:0045622""(regulation of T-helper cell differentiation)|go:""GO:0050778""(positive regulation of immune response)|go:""GO:0050870""(positive regulation of T cell activation)|go:""GO:0050890""(cognition)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|go:""GO:0120281""(autolysosome membrane)|go:""GO:2000516""(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|interpro:IPR050160|mint:P01903|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:1ZGL|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|rcsb pdb:7N19|rcsb pdb:7NZE|rcsb pdb:7O00|rcsb pdb:7YX9|rcsb pdb:7YXB|rcsb pdb:7Z0Q|rcsb pdb:8CMB|rcsb pdb:8CMC|rcsb pdb:8CMD|rcsb pdb:8CME|rcsb pdb:8CMF|rcsb pdb:8CMG|rcsb pdb:8CMH|rcsb pdb:8CMI|rcsb pdb:8EUQ|rcsb pdb:8PJE|rcsb pdb:8PJF|rcsb pdb:8PJG|rcsb pdb:8TBP|rcsb pdb:8TRL|rcsb pdb:8TRQ|rcsb pdb:8TRR|rcsb pdb:8VRW|rcsb pdb:8VSJ|rcsb pdb:9B7B|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:NP_061984.2|panther:PTHR19944(orthology-group)"	interpro:IPR051551	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	rogid:kFqNelFqfI7J+vafdsofmQ0p0zA632	intact-crc:D468E5602719566B|rigid:nAKUjSubXsKD4dtxD+cldTe4noI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P63104	uniprotkb:Q8CZY0	intact:EBI-347088|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6NUR9|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1	intact:EBI-2843763	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:q8czy0_yerpe(display_long)|uniprotkb:y3182(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848879|imex:IM-13779-5307	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000164924.18(gene)|ensembl:ENST00000353245.7(transcript)|ensembl:ENST00000395951.7(transcript)|ensembl:ENST00000395953.6(transcript)|ensembl:ENST00000395956.7(transcript)|ensembl:ENST00000395957.6(transcript)|ensembl:ENST00000395958.6(transcript)|ensembl:ENST00000419477.6(transcript)|ensembl:ENST00000457309.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0001525""(angiogenesis)|go:""GO:0003016""(respiratory system process)|go:""GO:0003723""(RNA binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006605""(protein targeting)|go:""GO:0007165""(signal transduction)|go:""GO:0008039""(synaptic target recognition)|go:""GO:0008104""(protein localization)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030324""(lung development)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031982""(vesicle)|go:""GO:0035148""(tube formation)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042470""(melanosome)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0050815""(phosphoserine residue binding)|go:""GO:0051683""(establishment of Golgi localization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070372""(regulation of ERK1 and ERK2 cascade)|go:""GO:0072562""(blood microparticle)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090168""(Golgi reassembly)|go:""GO:0098686""(hippocampal mossy fiber to CA3 synapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0140297""(DNA-binding transcription factor binding)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1900181""(negative regulation of protein localization to nucleus)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63104|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5J31|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|rcsb pdb:7MFD|rcsb pdb:7MFE|rcsb pdb:7MFF|rcsb pdb:7Q16|rcsb pdb:7ZIT|rcsb pdb:8A9G|rcsb pdb:8AH2|rcsb pdb:8QDV|rcsb pdb:8WE2|rcsb pdb:8WF6|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|reactome:R-HSA-9735871|reactome:R-HSA-9755779|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|efo:""Orphanet:178469""|panther:PTHR18860(orthology-group)|ensembl:ENSP00000309503.3|ensembl:ENSP00000379281.3|ensembl:ENSP00000379283.2|ensembl:ENSP00000379286.3|ensembl:ENSP00000379287.2|ensembl:ENSP00000379288.2|ensembl:ENSP00000395114.2|ensembl:ENSP00000398599.1|ensembl:ENST00000522542.5|ensembl:ENSP00000430072.1"	"interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR041954|interpro:IPR050612"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/24	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:Y5d3heMPjpe23bUutQ9OKW+v73g632	intact-crc:CA6ECE8234776CC4|rigid:lu517TdbU0tGoyfP2mi9sx3tyD4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GX38	uniprotkb:Q15942	intact:EBI-2841288|uniprotkb:A0A0H2W637|uniprotkb:Q74SI0|uniprotkb:A0A384LBC5|uniprotkb:Q7CJG2|uniprotkb:A0A380PEL1	intact:EBI-444225|ensembl:ENSP00000324422.5|ensembl:ENSP00000494798.1|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	psi-mi:a0a2u2gx38_yerpe(display_long)|uniprotkb:YPO2999(locus name)	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848900|imex:IM-13779-5308	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|refseq:YP_002347923.1|go:""GO:0019898""(extrinsic component of membrane)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0030313""(cell envelope)|go:""GO:1990195""(macrolide transmembrane transporter complex)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|refseq:WP_002208495.1|interpro:IPR030190"	"ensembl:ENSG00000159840.16(gene)|ensembl:ENSG00000285443.2(gene)|ensembl:ENST00000322764.10(transcript)|ensembl:ENST00000646695.2(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0046872""(metal ion binding)|go:""GO:0071346""(cellular response to type II interferon)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15942|refseq:NP_001010972.1|refseq:NP_003452.1|panther:PTHR24212(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:sdWXUSDDDoa4ne7FHbQ56e9RFP4632	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	intact-crc:89CFFA4DD6025FBF|rigid:twLzU6tpaIoRLhLCamXXDc3eiXM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15942	uniprotkb:A0A6B3VCW6	intact:EBI-444225|ensembl:ENSP00000324422.5|ensembl:ENSP00000494798.1|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	intact:EBI-2846132	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:a0a6b3vcw6_yerpe(display_long)|uniprotkb:YP_3785(locus name)|uniprotkb:y3786(locus name)|uniprotkb:sbcC3(gene name)|psi-mi:sbcC3(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848893|imex:IM-13779-5305	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000159840.16(gene)|ensembl:ENSG00000285443.2(gene)|ensembl:ENST00000322764.10(transcript)|ensembl:ENST00000646695.2(transcript)|go:""GO:0001725""(stress fiber)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0046872""(metal ion binding)|go:""GO:0071346""(cellular response to type II interferon)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15942|refseq:NP_001010972.1|refseq:NP_003452.1|panther:PTHR24212(orthology-group)"	uniprotkb:Q8CKB6(uniprot-removed-ac)|refseq:WP_002209173.1|interpro:IPR027417	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	rogid:JAJQ2/SqTxwkVfzJ9zXmGfJ8osk632	intact-crc:F621CAA3B3C61201|rigid:o/lprtZRUOLsXrrq8VecnAxIug8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IYH5	uniprotkb:Q7ARD3	intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837.3	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848886|imex:IM-13779-5304	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|refseq:XP_016856459.1|dip:DIP-47289N|ensembl:ENSG00000036549.13(gene)|ensembl:ENST00000370801.8(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0006325""(chromatin organization)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0035064""(methylated histone binding)|go:""GO:0045995""(regulation of embryonic development)|go:""GO:0051302""(regulation of cell division)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0070577""(lysine-acetylated histone binding)|go:""GO:0072686""(mitotic spindle)|go:""GO:0090043""(regulation of tubulin deacetylation)|go:""GO:0140566""(histone reader activity)|go:""GO:0140672""(ATAC complex)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|mint:Q8IYH5|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|reactome:R-HSA-9772755|panther:PTHR22705(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:B909E32D823EEFE0|rigid:uxHlkw2KiWamrYjP78wr4wX+E9M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01892	uniprotkb:A0A2S9PLS3	intact:EBI-2839473|uniprotkb:Q9TPY0|uniprotkb:Q29680|uniprotkb:Q29899|uniprotkb:P06338|uniprotkb:P30445|uniprotkb:Q95352|uniprotkb:Q9TQI3|uniprotkb:Q95380|uniprotkb:P30444|uniprotkb:Q9TPX8|uniprotkb:O19619|uniprotkb:P30446|uniprotkb:Q9TQH5|uniprotkb:P10313|uniprotkb:Q9TPX9|uniprotkb:P30514|uniprotkb:Q29837	intact:EBI-2841789|uniprotkb:Q74RP0|uniprotkb:A0A384KVM3|uniprotkb:Q0WJ02|uniprotkb:Q7CGH6	psi-mi:1a02_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A*02(gene name synonym)	psi-mi:a0a2s9pls3_yerpe(display_long)|uniprotkb:nfxD(gene name)|psi-mi:nfxD(display_short)|uniprotkb:Topoisomerase IV subunit B(gene name synonym)|uniprotkb:parE(gene name synonym)|uniprotkb:YPO0668(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848872|imex:IM-13779-5303	author score:2|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"rcsb pdb:4MNQ|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5HYJ|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5HHM|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E6I|rcsb pdb:5IRO|rcsb pdb:6D7G|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0030881""(beta-2-microglobulin binding)|go:""GO:0070971""(endoplasmic reticulum exit site)|rcsb pdb:4EMZ|rcsb pdb:4EN2|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|go:""GO:0031901""(early endosome membrane)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0000139""(Golgi membrane)|go:""GO:0071556""(obsolete integral component of lumenal side of endoplasmic reticulum membrane)|go:""GO:0042612""(MHC class I protein complex)|go:""GO:0060333""(type II interferon-mediated signaling pathway)|go:""GO:0050690""|go:""GO:0060337""(type I interferon-mediated signaling pathway)|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|go:""GO:0002486""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:""GO:0009986""(cell surface)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0046977""(TAP binding)|go:""GO:2000568""(positive regulation of memory T cell activation)|rcsb pdb:3QFD|rcsb pdb:4K7F|go:""GO:0002479""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:""GO:0002480""(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:""GO:0030670""(phagocytic vesicle membrane)|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:5NMG|rcsb pdb:5NHT|rcsb pdb:5NQK|rcsb pdb:4WUU|rcsb pdb:4E5X|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:2000566""(positive regulation of CD8-positive, alpha-beta T cell proliferation)|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:4I4W|rcsb pdb:5EOT|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:3TO2|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4EUP|go:""GO:0001916""(positive regulation of T cell mediated cytotoxicity)|go:""GO:0042605""(peptide antigen binding)|rcsb pdb:4FTV|rcsb pdb:5E9D|rcsb pdb:5C07|rcsb pdb:5C08|go:""GO:0005102""(signaling receptor binding)|go:""GO:0002474""(antigen processing and presentation of peptide antigen via MHC class I)|go:""GO:0005886""(plasma membrane)|go:""GO:0050776""(regulation of immune response)|ensembl:ENST00000457879|ensembl:ENST00000547271|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:""GO:0042608""(T cell receptor binding)|rcsb pdb:4L3E|ensembl:ENSG00000235657|ensembl:ENSP00000403575|ensembl:ENSP00000447962|go:""GO:0002726""(positive regulation of T cell cytokine production)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:2001187""(positive regulation of CD8-positive, alpha-beta T cell activation)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4OV5|rcsb pdb:4UQ3|ensembl:ENSG00000227715|ensembl:ENSP00000448077|ensembl:ENST00000547522|rcsb pdb:5SWQ|rcsb pdb:4WJ5|go:""GO:0003723""(RNA binding)|go:""GO:0055038""(recycling endosome membrane)|rcsb pdb:5E00|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|go:""GO:0051290""(protein heterotetramerization)|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5N1Y|go:""GO:0002250""(adaptive immune response)|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:5ENW|reactome:R-HSA-8866654|rcsb pdb:5JZI|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5TEZ|rcsb pdb:5WSH|mint:P01892|rcsb pdb:5N6B|rcsb pdb:5W1W|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|go:""GO:0002485""(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:""GO:0036037""(CD8-positive, alpha-beta T cell activation)|go:""GO:0042590""(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:""GO:0042610""(CD8 receptor binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0062061""(TAP complex binding)|rcsb pdb:6G3J"	"interpro:IPR006171(TOPRIM)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR005737(DNA topoisomerase IV, subunit B, Gram-negative)|interpro:IPR018522|go:""GO:0003677""(DNA binding)|go:""GO:0003918""(""DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005694""(chromosome)|go:""GO:0006265""(DNA topological change)|go:""GO:0007059""(chromosome segregation)|go:""GO:0034335""(DNA negative supercoiling activity)|refseq:YP_002345736.1|refseq:WP_002212181.1|interpro:IPR036890|panther:PTHR45866(orthology-group)"	"psi-mi:""MI:0469""(intact)"	"no-uniprot-update:Deprecated HLA-A AC, merged into a different UniProt canonical but we have mutation features in variable positions.|comment:""\""Allele =A*02:01:01:01\""""|comment:""\""Allele =A*02:01:01:01 according to IPD-IMGT/HLA database\"""""	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oTL0BWZeACoxMc++WgT0XDz+sNg9606	rogid:KIv5q/TV/0ZL6T8o4DD+ZUm2jNM632	intact-crc:9C46313885310C6F|rigid:u0ApxVRfpArI24CeOshJv4+P/FY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43264	uniprotkb:Q8ZAN0	intact:EBI-1001217|uniprotkb:A1A528|ensembl:ENSP00000200135.3	intact:EBI-2842242|uniprotkb:Q0WAP3	psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short)	psi-mi:fadb_yerpe(display_long)|uniprotkb:fadB(gene name)|psi-mi:fadB(display_short)|uniprotkb:YPO3766(locus name)|uniprotkb:y0464(locus name)|uniprotkb:YP_3282(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848907|imex:IM-13779-5313	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004715.1|dip:DIP-36471N|ensembl:ENSG00000086827.9(gene)|ensembl:ENST00000200135.8(transcript)|go:""GO:0000070""(mitotic sister chromatid segregation)|go:""GO:0000132""(establishment of mitotic spindle orientation)|go:""GO:0000776""(kinetochore)|go:""GO:0000922""(spindle pole)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005828""(kinetochore microtubule)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0007030""(Golgi organization)|go:""GO:0007080""(mitotic metaphase chromosome alignment)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0007096""(regulation of exit from mitosis)|go:""GO:0015031""(protein transport)|go:""GO:0016020""(membrane)|go:""GO:0019237""(centromeric DNA binding)|go:""GO:0034501""(protein localization to kinetochore)|go:""GO:0051301""(cell division)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0051988""(regulation of attachment of spindle microtubules to kinetochore)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0070939""(Dsl1/NZR complex)|go:""GO:1990423""(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|interpro:IPR046362|interpro:IPR048343|interpro:IPR048344|interpro:IPR055148|mint:O43264|rcsb pdb:7QPG|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|panther:PTHR12205(orthology-group)"	"interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|interpro:IPR012799(Fatty oxidation complex, alpha subunit FadB)|interpro:IPR029045|go:""GO:0004165""(""delta(3)-delta(2)-enoyl-CoA isomerase activity"")|go:""GO:0004300""(enoyl-CoA hydratase activity)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0008692""(3-hydroxybutyryl-CoA epimerase activity)|go:""GO:0016509""(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0036125""(fatty acid beta-oxidation multienzyme complex)|go:""GO:0070403""(NAD+ binding)|refseq:WP_002211546.1|interpro:IPR036291|refseq:YP_002348645.1|interpro:IPR050136|panther:PTHR43612(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/10	rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606	rogid:zUCGFSdEv7X+WT+PNMNgwgSM+4c632	intact-crc:E293D9CB75DD5820|rigid:KlFgPCRF2t1Y6hwiNPn4k3DgWDo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43309	uniprotkb:Q0WDE1	intact:EBI-1210440|uniprotkb:O43724|ensembl:ENSP00000507347.1|uniprotkb:A0A024RCI2|uniprotkb:A8K187|intact:EBI-8639902|intact:MINT-8162985	intact:EBI-2848934|uniprotkb:Q74SY9|uniprotkb:Q8D0U7	psi-mi:zsc12_human(display_long)|uniprotkb:ZSCAN12(gene name)|psi-mi:ZSCAN12(display_short)|uniprotkb:KIAA0426(gene name synonym)|uniprotkb:ZNF305(gene name synonym)|uniprotkb:ZNF96(gene name synonym)|uniprotkb:Zinc finger protein 96(gene name synonym)|uniprotkb:Zinc finger protein 305(gene name synonym)	psi-mi:prmb_yerpe(display_long)|uniprotkb:prmB(gene name)|psi-mi:prmB(display_short)|uniprotkb:N5-glutamine methyltransferase PrmB(gene name synonym)|uniprotkb:YPO2750(locus name)|uniprotkb:YP_2413(locus name)|uniprotkb:y1584(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848939|imex:IM-13779-5310	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_016867017.1|refseq:NP_001156863.1|refseq:XP_011513316.1|refseq:XP_011513317.1|ensembl:ENSG00000158691.16(gene)|ensembl:ENST00000684592.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|interpro:IPR050752|mint:O43309|panther:PTHR23226(orthology-group)"	"interpro:IPR029063|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004556(Modification methylase HemK)|interpro:IPR017127(""Protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific"")|interpro:IPR007848(Methyltransferase small)|refseq:WP_002209710.1|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005829""(cytosol)|go:""GO:0032259""(methylation)|go:""GO:0036009""(protein-glutamine N-methyltransferase activity)|refseq:YP_002347697.1|panther:PTHR47806(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NeS2fgSdvhN7fiSxc9wBea0MasY9606	rogid:E0TcJR1cPqw7XzHhfs/tgH45UN8632	intact-crc:65DA9B13967951BF|rigid:lcK9OBtmqQ3/qcKj4vAN5KMRVnU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UGI0	uniprotkb:Q8D171	intact:EBI-527853|uniprotkb:Q5SQP6|uniprotkb:B4DZ98|uniprotkb:Q69YK3|uniprotkb:D3DRF4|ensembl:ENSP00000352676.4	intact:EBI-2848946|uniprotkb:Q74WX6	psi-mi:zran1_human(display_long)|uniprotkb:Zinc finger Ran-binding domain-containing protein 1(gene name synonym)|uniprotkb:ZRANB1(gene name)|psi-mi:ZRANB1(display_short)|uniprotkb:TRABID(gene name synonym)|uniprotkb:TRAF-binding domain-containing protein(gene name synonym)	psi-mi:q8d171_yerpe(display_long)|uniprotkb:Flavin transferase(gene name synonym)|uniprotkb:YP_0699(locus name)|uniprotkb:y0957(locus name)|uniprotkb:apbE(gene name)|psi-mi:apbE(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848951|imex:IM-13779-5311	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060050.2|refseq:XP_005269983.1|ensembl:ENSG00000019995.6(gene)|ensembl:ENST00000359653.4(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016477""(cell migration)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0022604""(regulation of cell morphogenesis)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0031593""(polyubiquitin modification-dependent protein binding)|go:""GO:0035523""(protein K29-linked deubiquitination)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0071947""(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:""GO:0101005""(deubiquitinase activity)|go:""GO:1990168""(protein K33-linked deubiquitination)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR036443|interpro:IPR041294|interpro:IPR049768|interpro:IPR051346|mint:Q9UGI0|rcsb pdb:3ZRH|rcsb pdb:5AF6|reactome:R-HSA-195253|reactome:R-HSA-5689896|dip:DIP-33806N|panther:PTHR13367(orthology-group)|refseq:XP_016871846.1"	"interpro:IPR003374(ApbE-like lipoprotein)|interpro:IPR024932|go:""GO:0016740""(transferase activity)|go:""GO:0046872""(metal ion binding)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/cHOFsN7yB+8MUyL3cAG1v5MUAc9606	rogid:VXikgEO7mfUoKYWlB+IfHjyfdFA632	intact-crc:8EE296D2D654A09C|rigid:6UAVqPZk9ypQ38HZyysOPbHLSoI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1Q0	uniprotkb:Q9BR11	intact:EBI-2842423	intact:EBI-2818202|uniprotkb:Q9BV30|uniprotkb:Q5JZH2|uniprotkb:Q9BR12|ensembl:ENSP00000361601.1	psi-mi:q8d1q0_yerpe(display_long)|uniprotkb:gabD(gene name)|psi-mi:gabD(display_short)|uniprotkb:gabD_1(gene name synonym)|uniprotkb:NCTC5923_00695(orf name)|uniprotkb:y0176(locus name)	psi-mi:zswm1_human(display_long)|uniprotkb:ZSWIM1(gene name)|psi-mi:ZSWIM1(display_short)|uniprotkb:C20orf162(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848927|imex:IM-13779-5312	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR029510|go:""GO:0036243""(""succinate-semialdehyde dehydrogenase (NADP+) activity"")|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR050740"	"refseq:XP_011527402.1|refseq:NP_542170.3|refseq:XP_005260667.1|refseq:XP_005260668.1|ensembl:ENSG00000168612.5(gene)|ensembl:ENST00000372523.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0008270""(zinc ion binding)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR045563|interpro:IPR048324|interpro:IPR048326|interpro:IPR052579|mint:Q9BR11|panther:PTHR31569(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:txdyWoCIYMZColLNszJEOPdNYNk632	rogid:y3Xs763546XsaLlfSqM7WqlH2gw9606	intact-crc:4C205D070AB34254|rigid:qziKKFa7Q3hONVQhvWmr4TwpAQU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BR11	uniprotkb:Q9F290	intact:EBI-2818202|uniprotkb:Q9BV30|uniprotkb:Q5JZH2|uniprotkb:Q9BR12|ensembl:ENSP00000361601.1	intact:EBI-2848917|uniprotkb:Q7CJX2|uniprotkb:Q74VW8|uniprotkb:A0A384LNI0|uniprotkb:A0A1U8QEG5|uniprotkb:A0A2U2GUS9	psi-mi:zswm1_human(display_long)|uniprotkb:ZSWIM1(gene name)|psi-mi:ZSWIM1(display_short)|uniprotkb:C20orf162(gene name synonym)	psi-mi:q9f290_yerpe(display_long)|uniprotkb:yapC(gene name)|psi-mi:yapC(display_short)|uniprotkb:YPO2796(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848914|imex:IM-13779-5309	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011527402.1|refseq:NP_542170.3|refseq:XP_005260667.1|refseq:XP_005260668.1|ensembl:ENSG00000168612.5(gene)|ensembl:ENST00000372523.1(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0008270""(zinc ion binding)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR045563|interpro:IPR048324|interpro:IPR048326|interpro:IPR052579|mint:Q9BR11|panther:PTHR31569(orthology-group)"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR004899(Pertactin)|interpro:IPR003991(Pertactin virulence factor, C-terminal)|interpro:IPR012332(Phage P22 tailspike)|refseq:WP_002209752.1|go:""GO:0009279""(cell outer membrane)|interpro:IPR036709|refseq:YP_002347738.1|interpro:IPR051551|panther:PTHR35037(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y3Xs763546XsaLlfSqM7WqlH2gw9606	rogid:pdr4YGdh7vzVjMHR+QhHJFQ2SUE632	intact-crc:7352A4387BA69A94|rigid:gr5rvaBbDVW4AX/NeMTT/7QWCJY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VCW6	uniprotkb:Q07157	intact:EBI-2846132	intact:EBI-79553|uniprotkb:B4E3K1|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6|ensembl:ENSP00000281537.7|ensembl:ENSP00000484535.2	psi-mi:a0a6b3vcw6_yerpe(display_long)|uniprotkb:YP_3785(locus name)|uniprotkb:y3786(locus name)|uniprotkb:sbcC3(gene name)|psi-mi:sbcC3(display_short)	psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein ZO-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848971|imex:IM-13779-5317	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q8CKB6(uniprot-removed-ac)|refseq:WP_002209173.1|interpro:IPR027417	"refseq:NP_003248.3|refseq:NP_783297.2|panther:PTHR13865(orthology-group)|ensembl:ENSG00000104067.17(gene)|ensembl:ENSG00000277401.4(gene)|ensembl:ENST00000346128.10(transcript)|ensembl:ENST00000621049.4(transcript)|go:""GO:0002102""(podosome)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005921""(gap junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034334""(adherens junction maintenance)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0036305""(ameloblast differentiation)|go:""GO:0042995""(cell projection)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043296""(apical junction complex)|go:""GO:0045177""(apical part of cell)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0070160""(tight junction)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0090557""(establishment of endothelial intestinal barrier)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1901888""(regulation of cell junction assembly)|go:""GO:1902396""(protein localization to bicellular tight junction)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1905605""(positive regulation of blood-brain barrier permeability)|go:""GO:2000049""(positive regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035597|interpro:IPR036028|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|reactome:R-HSA-9705677"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JAJQ2/SqTxwkVfzJ9zXmGfJ8osk632	rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606	intact-crc:679F8755BC6A1851|rigid:p00G8/NlS1+MfAoeAzALRQpUUJQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B749	uniprotkb:Q6NXT4	intact:EBI-2842996|uniprotkb:Q74V98|uniprotkb:Q0WGP3|uniprotkb:Q7CHR5|uniprotkb:A0A384LAC1	intact:EBI-2849005|uniprotkb:Q96NC3|uniprotkb:A5YM45|uniprotkb:Q8N5C9|uniprotkb:B7Z901|ensembl:ENSP00000282587.5	psi-mi:a0a3n4b749_yerpe(display_long)|uniprotkb:YPO1529(locus name)	psi-mi:znt6_human(display_long)|uniprotkb:SLC30A6(gene name)|psi-mi:SLC30A6(display_short)|uniprotkb:ZNT6(gene name synonym)|uniprotkb:Solute carrier family 30 member 6(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849002|imex:IM-13779-5314	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010977(Aromatic-L-amino-acid decarboxylase)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002211877.1|go:""GO:0005737""(cytoplasm)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0016831""(carboxy-lyase activity)|go:""GO:0019752""(carboxylic acid metabolic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:YP_002346545.1|panther:PTHR45677(orthology-group)"	"refseq:NP_001180442.1|refseq:NP_001180443.1|refseq:NP_060434.2|refseq:NP_001180444.1|ensembl:ENSG00000152683.14(gene)|ensembl:ENST00000282587.9(transcript)|go:""GO:0005385""(zinc ion transmembrane transporter activity)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006829""(zinc ion transport)|go:""GO:0015297""(antiporter activity)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0071579""(regulation of zinc ion transport)|go:""GO:1904257""(zinc ion import into Golgi lumen)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR052005|mint:Q6NXT4|panther:PTHR46531(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Uex6pAvRG3FNG1VCbilPXw5bliY632	rogid:87Lnmo7ZMC5jeA4yaMQdauspboE9606	intact-crc:0164572E47CC6E97|rigid:TAsVEUX80KMDRoGzx+n9NXDZjCw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q07157	uniprotkb:A0A5P8YFN7	intact:EBI-79553|uniprotkb:B4E3K1|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6|ensembl:ENSP00000281537.7|ensembl:ENSP00000484535.2	intact:EBI-2848958	psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein ZO-1(gene name synonym)	psi-mi:a0a5p8yfn7_yerpe(display_long)|uniprotkb:hrpA(gene name)|psi-mi:hrpA(display_short)|uniprotkb:NCTC5923_02603(orf name)|uniprotkb:YP_2109(locus name)|uniprotkb:y2011(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848964|imex:IM-13779-5315	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003248.3|refseq:NP_783297.2|panther:PTHR13865(orthology-group)|ensembl:ENSG00000104067.17(gene)|ensembl:ENSG00000277401.4(gene)|ensembl:ENST00000346128.10(transcript)|ensembl:ENST00000621049.4(transcript)|go:""GO:0002102""(podosome)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005921""(gap junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034334""(adherens junction maintenance)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0036305""(ameloblast differentiation)|go:""GO:0042995""(cell projection)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043296""(apical junction complex)|go:""GO:0045177""(apical part of cell)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0070160""(tight junction)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0090557""(establishment of endothelial intestinal barrier)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1901888""(regulation of cell junction assembly)|go:""GO:1902396""(protein localization to bicellular tight junction)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1905605""(positive regulation of blood-brain barrier permeability)|go:""GO:2000049""(positive regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035597|interpro:IPR036028|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|reactome:R-HSA-9705677"	"interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007502(Helicase-associated region)|interpro:IPR010222(RNA helicase, ATP-dependent DEAH box, HrpA type)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR024590|interpro:IPR027417|uniprotkb:A0A6B3T5A4(uniprot-removed-ac)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR048333|refseq:WP_002211005.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606	rogid:aLxVjye9aRvQwd2fQxeIYUCRG+w632	intact-crc:0521FB829EA853CE|rigid:VpxLAIlkJHtAHvfgEsiq5lgVC7g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZFV7	uniprotkb:Q6PML9	intact:EBI-2848990|uniprotkb:Q0WGK5	intact:EBI-2818242|uniprotkb:Q8TBB2|uniprotkb:Q7Z5I7|uniprotkb:Q4W5B6|uniprotkb:Q9Y6R2|ensembl:ENSP00000264451.6	psi-mi:assy_yerpe(display_long)|uniprotkb:argG(gene name)|psi-mi:argG(display_short)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:YPO1570(locus name)|uniprotkb:y2595(locus name)|uniprotkb:YP_1458(locus name)	psi-mi:znt9_human(display_long)|uniprotkb:SLC30A9(gene name)|psi-mi:SLC30A9(display_short)|uniprotkb:Zinc transporter 9(gene name synonym)|uniprotkb:C4orf1(gene name synonym)|uniprotkb:HUEL(gene name synonym)|uniprotkb:Human embryonic lung protein(gene name synonym)|uniprotkb:Solute carrier family 30 member 9(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848995|imex:IM-13779-5316	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023437|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR018223|interpro:IPR024074|interpro:IPR024073|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:WP_002211920.1|go:""GO:0000050""(urea cycle)|go:""GO:0000053""(argininosuccinate metabolic process)|go:""GO:0004055""(argininosuccinate synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0042803""(protein homodimerization activity)|interpro:IPR048267|interpro:IPR048268|refseq:YP_002346583.1|panther:PTHR11587(orthology-group)"	"ensembl:ENSG00000014824.14(gene)|ensembl:ENST00000264451.12(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005385""(zinc ion transmembrane transporter activity)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006289""(nucleotide-excision repair)|go:""GO:0006829""(zinc ion transport)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0015297""(antiporter activity)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|interpro:IPR002524(Cation efflux protein)|interpro:IPR009061(Putative DNA binding)|interpro:IPR027469|interpro:IPR037129|interpro:IPR040177|mint:Q6PML9|rcsb pdb:2ENK|refseq:NP_006336.3|efo:""Orphanet:505242""|panther:PTHR13414(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Jwk0DC2erpxK85HEovRAmGtZZRo632	rogid:FOpcvusmMSLnk+espRUTV4ijPoQ9606	intact-crc:4724DE2D3A8FF0EA|rigid:OduDLmxPSn/sEmWYp1gHIPIiHhM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GZR6	uniprotkb:Q07157	intact:EBI-2848981|uniprotkb:Q74V88|uniprotkb:A0A0H2W2U0|uniprotkb:Q0WGM1|uniprotkb:Q7CHS3|uniprotkb:A0A384L5K8	intact:EBI-79553|uniprotkb:B4E3K1|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6|ensembl:ENSP00000281537.7|ensembl:ENSP00000484535.2	psi-mi:a0a2u2gzr6_yerpe(display_long)|uniprotkb:YPO1551(locus name)	psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein ZO-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2848978|imex:IM-13779-5318	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001509(NAD-dependent epimerase/dehydratase)|refseq:WP_002211898.1|interpro:IPR036291|refseq:YP_002346567.1|interpro:IPR051783	"refseq:NP_003248.3|refseq:NP_783297.2|panther:PTHR13865(orthology-group)|ensembl:ENSG00000104067.17(gene)|ensembl:ENSG00000277401.4(gene)|ensembl:ENST00000346128.10(transcript)|ensembl:ENST00000621049.4(transcript)|go:""GO:0002102""(podosome)|go:""GO:0005516""(calmodulin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005912""(adherens junction)|go:""GO:0005921""(gap junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007043""(cell-cell junction assembly)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030054""(cell junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031032""(actomyosin structure organization)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034334""(adherens junction maintenance)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0036305""(ameloblast differentiation)|go:""GO:0042995""(cell projection)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043296""(apical junction complex)|go:""GO:0045177""(apical part of cell)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045296""(cadherin binding)|go:""GO:0050839""(cell adhesion molecule binding)|go:""GO:0051493""(regulation of cytoskeleton organization)|go:""GO:0051497""(negative regulation of stress fiber assembly)|go:""GO:0070160""(tight junction)|go:""GO:0071896""(protein localization to adherens junction)|go:""GO:0090557""(establishment of endothelial intestinal barrier)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0150105""(protein localization to cell-cell junction)|go:""GO:1901888""(regulation of cell junction assembly)|go:""GO:1902396""(protein localization to bicellular tight junction)|go:""GO:1903672""(positive regulation of sprouting angiogenesis)|go:""GO:1905605""(positive regulation of blood-brain barrier permeability)|go:""GO:2000049""(positive regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000810""(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035597|interpro:IPR036028|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|reactome:R-HSA-9705677"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Djl6SMgYSl6vUPDrk8cvJP0HCrg632	rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606	intact-crc:E727B1EB9A7253B7|rigid:qDk3cJpCaXuhao5yJoOEFqXEUHE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PM91	uniprotkb:Q9P2E3	intact:EBI-2845565|uniprotkb:Q74XN3|uniprotkb:Q7CKA1|uniprotkb:A0A0H2W0J0|uniprotkb:Q0WBX7	intact:EBI-308745|uniprotkb:Q9BQM7|uniprotkb:Q9BQM8|uniprotkb:Q9H8C1|uniprotkb:Q9H9S2|uniprotkb:Q9NUM1|uniprotkb:Q9NWW1|ensembl:ENSP00000360817.1|ensembl:ENSP00000379412.1	psi-mi:a0a2s9pm91_yerpe(display_long)|uniprotkb:rbsC(gene name)|psi-mi:rbsC(display_short)|uniprotkb:YPO3315(locus name)	psi-mi:znfx1_human(display_long)|uniprotkb:ZNFX1(gene name)|psi-mi:ZNFX1(display_short)|uniprotkb:KIAA1404(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849041|imex:IM-13779-5320	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|refseq:WP_002209437.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:YP_002348211.1"	"refseq:NP_066363.1|ensembl:ENSG00000124201.15(gene)|ensembl:ENST00000371752.5(transcript)|ensembl:ENST00000396105.6(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0031380""(nuclear RNA-directed RNA polymerase complex)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0051607""(defense response to virus)|interpro:IPR000967(Zinc finger, NF-X1-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|interpro:IPR045055|interpro:IPR046439|interpro:IPR047187|mint:Q9P2E3|refseq:XP_006723899.1|panther:PTHR10887(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QdtHo9H/Vuz7QOXdAkSbm2MTatU632	rogid:2vNUbYE3//YGh0eabKbzldLESF49606	intact-crc:9EB1C5C73DF347FA|rigid:wfiz6L45f5rpW2ptBVHEnzbgaAs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43257	uniprotkb:Q8ZIX3	intact:EBI-347522|ensembl:ENSP00000304593.2|uniprotkb:Q6IB12	intact:EBI-2847981|uniprotkb:Q0WJU8	psi-mi:znhi1_human(display_long)|uniprotkb:Cyclin-G1-binding protein 1(gene name synonym)|uniprotkb:Zinc finger protein subfamily 4A member 1(gene name synonym)|uniprotkb:p18 Hamlet(gene name synonym)|uniprotkb:ZNHIT1(gene name)|psi-mi:ZNHIT1(display_short)|uniprotkb:CGBP1(gene name synonym)|uniprotkb:ZNFN4A1(gene name synonym)	psi-mi:epma_yerpe(display_long)|uniprotkb:epmA(gene name)|psi-mi:epmA(display_short)|uniprotkb:EF-P post-translational modification enzyme A(gene name synonym)|uniprotkb:EF-P-lysine lysyltransferase(gene name synonym)|uniprotkb:yjeA(gene name synonym)|uniprotkb:YPO0362(locus name)|uniprotkb:YP_0517(locus name)|uniprotkb:y0618(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849034|imex:IM-13779-5319	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000106400.12(gene)|ensembl:ENST00000305105.3(transcript)|go:""GO:0000786""(nucleosome)|go:""GO:0000812""(Swr1 complex)|go:""GO:0003015""(heart process)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0031491""(nucleosome binding)|go:""GO:0036335""(intestinal stem cell homeostasis)|go:""GO:0042393""(histone binding)|go:""GO:0042692""(muscle cell differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0055074""(calcium ion homeostasis)|go:""GO:0060261""(positive regulation of transcription initiation by RNA polymerase II)|go:""GO:1902164""(obsolete positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:""GO:1905458""(positive regulation of lymphoid progenitor cell differentiation)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR039723|mint:O43257|rcsb pdb:8X15|rcsb pdb:8X19|rcsb pdb:8X1C|refseq:NP_006340.1|panther:PTHR13093(orthology-group)"	"interpro:IPR004364(""Aminoacyl-tRNA synthetase, class II (D, K and N)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004525(Lysyl-tRNA synthetase-related protein)|interpro:IPR018149|refseq:WP_002209139.1|go:""GO:0000049""(tRNA binding)|go:""GO:0004824""(lysine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006430""(lysyl-tRNA aminoacylation)|go:""GO:0016880""(""acid-ammonia (or amide) ligase activity"")|refseq:YP_002345440.1|interpro:IPR045864|panther:PTHR42918(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Q7J5KSTTPql/B3mtDg1xvX0EWjw9606	rogid:Cq2TlRQJw1u1ex67uZKhwD4US2I632	intact-crc:53BBAB4E481F52A6|rigid:RLApK2cuGp47MixSqW1+LFMyhiI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P2E3	uniprotkb:A0A0H2W6W4	intact:EBI-308745|uniprotkb:Q9BQM7|uniprotkb:Q9BQM8|uniprotkb:Q9H8C1|uniprotkb:Q9H9S2|uniprotkb:Q9NUM1|uniprotkb:Q9NWW1|ensembl:ENSP00000360817.1|ensembl:ENSP00000379412.1	intact:EBI-2843643|uniprotkb:Q74RL4|uniprotkb:Q0WIX4|uniprotkb:Q7CGJ6|uniprotkb:A0A5P8YJ93|uniprotkb:A0A384LJE2	psi-mi:znfx1_human(display_long)|uniprotkb:ZNFX1(gene name)|psi-mi:ZNFX1(display_short)|uniprotkb:KIAA1404(gene name synonym)	psi-mi:a0a0h2w6w4_yerpe(display_long)|uniprotkb:YPO0700(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849048|imex:IM-13779-5322	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_066363.1|ensembl:ENSG00000124201.15(gene)|ensembl:ENST00000371752.5(transcript)|ensembl:ENST00000396105.6(transcript)|go:""GO:0002218""(activation of innate immune response)|go:""GO:0003723""(RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0031048""(regulatory ncRNA-mediated heterochromatin formation)|go:""GO:0031380""(nuclear RNA-directed RNA polymerase complex)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045087""(innate immune response)|go:""GO:0051607""(defense response to virus)|interpro:IPR000967(Zinc finger, NF-X1-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|interpro:IPR045055|interpro:IPR046439|interpro:IPR047187|mint:Q9P2E3|refseq:XP_006723899.1|panther:PTHR10887(orthology-group)"	"interpro:IPR008966(Adhesion, bacterial)|interpro:IPR000259(Fimbrial protein)|refseq:WP_002211456.1|go:""GO:0007155""(cell adhesion)|go:""GO:0009289""(pilus)|interpro:IPR036937|refseq:YP_002345764.1|interpro:IPR050263"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2vNUbYE3//YGh0eabKbzldLESF49606	rogid:Q8Cvuk8bSe5Of8+4jTNlsIg6fbw632	intact-crc:B31C34118D601337|rigid:KYIy089OnXL6ikgCcYV576Ar6Kc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NHG8	uniprotkb:Q8ZI64	intact:EBI-2849023|ensembl:ENSP00000323879.4	intact:EBI-2849016|uniprotkb:Q0WJ20|uniprotkb:Q7CGG6|uniprotkb:Q74RQ7	psi-mi:znrf2_human(display_long)|uniprotkb:ZNRF2(gene name)|psi-mi:ZNRF2(display_short)|uniprotkb:RNF202(gene name synonym)|uniprotkb:Protein Ells2(gene name synonym)|uniprotkb:RING finger protein 202(gene name synonym)|uniprotkb:Zinc/RING finger protein 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZNRF2(gene name synonym)	psi-mi:cca_yerpe(display_long)|uniprotkb:cca(gene name)|psi-mi:cca(display_short)|uniprotkb:YPO0650(locus name)|uniprotkb:y3529(locus name)|uniprotkb:YP_2965(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849027|imex:IM-13779-5321	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000180233.11(gene)|ensembl:ENST00000323037.5(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030659""(cytoplasmic vesicle membrane)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042734""(presynaptic membrane)|go:""GO:0042995""(cell projection)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0160177""(positive regulation of autophagosome-lysosome fusion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR051878|mint:Q8NHG8|reactome:R-HSA-983168|refseq:NP_667339.1|panther:PTHR46661(orthology-group)"	"interpro:IPR032828|interpro:IPR012006(tRNA nucleotidyltransferase, proteobacteria)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR002646(Polynucleotide adenylyltransferase region)|interpro:IPR043519|refseq:WP_002212197.1|go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0001680""(tRNA 3'-terminal CCA addition)|go:""GO:0004112""(cyclic-nucleotide phosphodiesterase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016791""(phosphatase activity)|go:""GO:0042245""(RNA repair)|go:""GO:0160016""(CCACCA tRNA nucleotidyltransferase activity)|refseq:YP_002345718.1|interpro:IPR050124|panther:PTHR47545(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UCQ9RCU6HBaX2ZpG8JHwUtcEvos9606	rogid:847M9rnKog0HyzhxU0h5vh+Jj7U632	intact-crc:04260C0C3044A737|rigid:0bAvtYwiKMXLPjpRC+QYLVyXzPA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q05481	uniprotkb:A0A2U2GXV0	intact:EBI-1105379|uniprotkb:A8K5E1|uniprotkb:B7Z6G6|ensembl:ENSP00000300619.6	intact:EBI-2840495|uniprotkb:Q74PJ9|uniprotkb:A0A0H2W8W4|uniprotkb:A0A384L2Q0|uniprotkb:Q7CL55	psi-mi:znf91_human(display_long)|uniprotkb:ZNF91(gene name)|psi-mi:ZNF91(display_short)|uniprotkb:Zinc finger protein HTF10(gene name synonym)|uniprotkb:Zinc finger protein HPF7(gene name synonym)	psi-mi:a0a2u2gxv0_yerpe(display_long)|uniprotkb:YPO3641(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849055|imex:IM-13779-5325	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003421.2|refseq:NP_001287880.1|ensembl:ENSG00000167232.14(gene)|ensembl:ENST00000300619.12(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010526""(transposable element silencing)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|panther:PTHR24376(orthology-group)"	refseq:WP_002210051.1|refseq:YP_002348526.1|interpro:IPR036869	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1fgAlEBioWwxwq2yZqBLhCqnnIs9606	rogid:SVf+9kCFQwgDlka34vEDmNYw9/Q632	intact-crc:AF964F4AE297FDEC|rigid:pv7i3l/xLx0k20eZETt3PNYYEZ4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H163	uniprotkb:P51815	intact:EBI-2849095|uniprotkb:Q74VM1|uniprotkb:Q0WH98|uniprotkb:Q7CHF6|uniprotkb:A0A384KHA9	intact:EBI-2799400|uniprotkb:Q6LDE0|uniprotkb:Q5JPG0|ensembl:ENSP00000359802.3|uniprotkb:A6NK62|uniprotkb:B3KRI7	psi-mi:a0a2u2h163_yerpe(display_long)|uniprotkb:YPO1315(locus name)	psi-mi:zn75d_human(display_long)|uniprotkb:ZNF75(gene name synonym)|uniprotkb:ZNF82(gene name synonym)|uniprotkb:Zinc finger protein 75(gene name synonym)|uniprotkb:Zinc finger protein 82(gene name synonym)|uniprotkb:ZNF75D(gene name)|psi-mi:ZNF75D(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849092|imex:IM-13779-5326	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006385(HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial)|refseq:WP_002215448.1|go:""GO:0016787""(hydrolase activity)|interpro:IPR036412|refseq:YP_002346340.1|interpro:IPR050582|panther:PTHR43344(orthology-group)"	"refseq:XP_011529693.1|refseq:NP_001171992.1|refseq:NP_009062.2|ensembl:ENSG00000186376.16(gene)|ensembl:ENST00000370766.8(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_005262526.1|panther:PTHR23226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CZMciP/S1SwtzGQyBQQdrmMpLg0632	rogid:tYDaDjocQC4o76OauxIXBlRL/4o9606	intact-crc:152067B44074C097|rigid:RaLzbermfkDSdGBqKRU/csnNuFk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q05481	uniprotkb:A0A2U2GY44	intact:EBI-1105379|uniprotkb:A8K5E1|uniprotkb:B7Z6G6|ensembl:ENSP00000300619.6	intact:EBI-2849062|uniprotkb:Q74TM9|uniprotkb:A0A0H2W5C9|uniprotkb:Q7CIP9|uniprotkb:A0A384KEN6	psi-mi:znf91_human(display_long)|uniprotkb:ZNF91(gene name)|psi-mi:ZNF91(display_short)|uniprotkb:Zinc finger protein HTF10(gene name synonym)|uniprotkb:Zinc finger protein HPF7(gene name synonym)	psi-mi:a0a2u2gy44_yerpe(display_long)|uniprotkb:YPO2337(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849067|imex:IM-13779-5323	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003421.2|refseq:NP_001287880.1|ensembl:ENSG00000167232.14(gene)|ensembl:ENST00000300619.12(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010526""(transposable element silencing)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|panther:PTHR24376(orthology-group)"	"interpro:IPR009061(Putative DNA binding)|interpro:IPR000551(Bacterial regulatory protein, MerR)|refseq:WP_002210990.1|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|refseq:YP_002347304.1|interpro:IPR047057|panther:PTHR30204(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1fgAlEBioWwxwq2yZqBLhCqnnIs9606	rogid:2AB9TojXYmX1MF51yL0cEmZlVL4632	intact-crc:0E19540ED65708F2|rigid:XOZp8pG8LT+zhaZFSRKw+F/d9Ck	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P51523	uniprotkb:A0A6M0NNK5	intact:EBI-2849074|uniprotkb:Q9UC18|uniprotkb:Q86XU8|uniprotkb:Q3ZCV9|uniprotkb:Q9NNX7|uniprotkb:Q9UC17|uniprotkb:B2RAK5|uniprotkb:Q5D057|uniprotkb:D3DXJ1|ensembl:ENSP00000331465.7|ensembl:ENSP00000376133.2|ensembl:ENSP00000445549.1	intact:EBI-2846580	psi-mi:znf84_human(display_long)|uniprotkb:ZNF84(gene name)|psi-mi:ZNF84(display_short)|uniprotkb:Zinc finger protein HPF2(gene name synonym)	psi-mi:a0a6m0nnk5_yerpe(display_long)|uniprotkb:y1846(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849085|imex:IM-13779-5324	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011533134.1|refseq:NP_001276900.1|refseq:NP_001276901.1|refseq:NP_001120844.1|refseq:NP_003419.3|refseq:XP_005266242.1|refseq:XP_005266243.1|ensembl:ENSG00000198040.11(gene)|ensembl:ENST00000327668.11(transcript)|ensembl:ENST00000392319.6(transcript)|ensembl:ENST00000539354.6(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:P51523|panther:PTHR24377(orthology-group)"	"uniprotkb:A0A6B3T7I9(uniprot-removed-ac)|interpro:IPR008635(Haemagluttinin motif)|interpro:IPR008640(Hep/Hag)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:""GO:0019867""(outer membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zsEc/0um2BHfMbCHJ7GFoH9Qwfo9606	rogid:yL2m6VTkA9R9Q4e4kurjcWXhQOY632	intact-crc:21DD61AA4A6F66A1|rigid:mtWIpdTioQ8/scLluF/lUjoD3pw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17036	uniprotkb:Q9RI12	intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667.4|ensembl:ENSP00000415358.1	intact:EBI-2849107|uniprotkb:O68717	psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym)	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849104|imex:IM-13779-5331	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526.19(gene)|ensembl:ENST00000299667.9(transcript)|ensembl:ENST00000424697.5(transcript)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008270""(zinc ion binding)|go:""GO:0030154""(cell differentiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045321""(leukocyte activation)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|panther:PTHR24381(orthology-group)"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	intact-crc:92CB898535D0E8EF|rigid:yAEGm6vwxm+Nr43FxztDHpag+r0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H1F8	uniprotkb:Q3KP31	intact:EBI-2847667|uniprotkb:Q74RN0|uniprotkb:Q0WIZ2|uniprotkb:Q7CGI4|uniprotkb:A0A384LC57	intact:EBI-2849119|uniprotkb:Q8NC99|uniprotkb:B7Z586|ensembl:ENSP00000342974.4	psi-mi:a0a2u2h1f8_yerpe(display_long)|uniprotkb:YPO0680(locus name)	psi-mi:zn791_human(display_long)|uniprotkb:ZNF791(gene name)|psi-mi:ZNF791(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849116|imex:IM-13779-5327	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR032816|interpro:IPR032818|refseq:WP_002212173.1|go:""GO:0005886""(plasma membrane)|refseq:YP_002345746.1|panther:PTHR30353(orthology-group)"	"refseq:NP_699189.2|ensembl:ENSG00000173875.14(gene)|ensembl:ENST00000343325.9(transcript)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR050589|reactome:R-HSA-212436|refseq:XP_016881901.1|panther:PTHR24379(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BqFEmH35pLhf+8qQYRQH+W5Vfmg632	rogid:nUyJHR51GeJKyWEXaBwEcSfH3yg9606	intact-crc:34696C3A3D331C80|rigid:vxZXcj1Ul5Lp++wQTp81s0SrLMQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N1G0	uniprotkb:Q8ZBU9	intact:EBI-1210558|uniprotkb:Q68DQ8|uniprotkb:Q9H937|uniprotkb:Q9P2A7|uniprotkb:D3DV17|ensembl:ENSP00000319829.5|ensembl:ENSP00000336620.5	intact:EBI-2849165|uniprotkb:Q0WBZ9|uniprotkb:Q8CWH8	psi-mi:zn687_human(display_long)|uniprotkb:ZNF687(gene name)|psi-mi:ZNF687(display_short)|uniprotkb:KIAA1441(gene name synonym)	psi-mi:trmd_yerpe(display_long)|uniprotkb:trmD(gene name)|psi-mi:trmD(display_short)|uniprotkb:M1G-methyltransferase(gene name synonym)|uniprotkb:tRNA [GM37] methyltransferase(gene name synonym)|uniprotkb:YPO3293(locus name)|uniprotkb:y0896(locus name)|uniprotkb:YP_0393(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849162|imex:IM-13779-5329	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000143373.18(gene)|ensembl:ENST00000324048.9(transcript)|ensembl:ENST00000336715.11(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041697|interpro:IPR045914|mint:Q8N1G0|refseq:NP_001291692.1|refseq:NP_001291693.1|refseq:NP_065883.1|refseq:XP_011508114.1|refseq:XP_011508115.1|panther:PTHR47222(orthology-group)"	"refseq:WP_002222284.1|interpro:IPR016009(""tRNA (guanine-N1-)-methyltransferase"")|interpro:IPR002649(""tRNA (guanine-N1-)-methyltransferase, bacteria"")|interpro:IPR029026|interpro:IPR029028|go:""GO:0002939""(tRNA N1-guanine methylation)|go:""GO:0005829""(cytosol)|go:""GO:0052906""(""tRNA (guanine(37)-N1)-methyltransferase activity"")|interpro:IPR023148|refseq:YP_002348189.1|panther:PTHR46417(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NR6q/E7oFHWVxeOkmRTyG6HKTvQ9606	rogid:1ZhDax/Jq3MGthugA9oqiOYbbc4632	intact-crc:227E1769ECD40160|rigid:OHNlMPPd6474UiGKcULHyqVv2DM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N8C0	uniprotkb:A0A2U2H346	intact:EBI-2849128|uniprotkb:Q2VPJ8	intact:EBI-2849136|uniprotkb:Q74TG8|uniprotkb:A0A0H2W5H4|uniprotkb:Q0WEC0|uniprotkb:Q7CIT1|uniprotkb:A0A384KWM5	psi-mi:zn781_human(display_long)|uniprotkb:ZNF781(gene name)|psi-mi:ZNF781(display_short)	psi-mi:a0a2u2h346_yerpe(display_long)|uniprotkb:YPO2403(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849133|imex:IM-13779-5330	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_689818.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0046872""(metal ion binding)|interpro:IPR039938|interpro:IPR036236|panther:PTHR14947(orthology-group)"	"interpro:IPR010231(SUF system FeS cluster assembly, SufB)|interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|refseq:WP_002211808.1|go:""GO:0016226""(iron-sulfur cluster assembly)|interpro:IPR037284|refseq:YP_002347368.1|interpro:IPR045595"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PMXyo2tdtmt+8A/REFjTnOOAujY9606	rogid:DkCekEHB1T0D0zddmetEadbmVDk632	intact-crc:4B6BAE6E92CC1AF3|rigid:JW+/EYz6F8rDH1kqj6XDNWL8j6M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H0M8	uniprotkb:Q9Y462	intact:EBI-2849144|uniprotkb:Q74XP9|uniprotkb:A0A3N4B5K6|uniprotkb:A0A0H2W284|uniprotkb:Q7CKB5|uniprotkb:A0A384KE37	intact:EBI-2849152|uniprotkb:Q9Y4J6|uniprotkb:Q6NX42|uniprotkb:B4DSV4|ensembl:ENSP00000276123.3|ensembl:ENSP00000362260.3	psi-mi:a0a2u2h0m8_yerpe(display_long)|uniprotkb:fumA(gene name)|psi-mi:fumA(display_short)|uniprotkb:fumB(gene name synonym)|uniprotkb:YPO3335(locus name)	psi-mi:zn711_human(display_long)|uniprotkb:ZNF711(gene name)|psi-mi:ZNF711(display_short)|uniprotkb:CMPX1(gene name synonym)|uniprotkb:ZNF6(gene name synonym)|uniprotkb:Zinc finger protein 6(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849149|imex:IM-13779-5328	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020557|refseq:WP_002209418.1|interpro:IPR004646(Fe-S type hydro-lyases tartrate/fumarate alpha region)|interpro:IPR004647(Fe-S type hydro-lyases tartrate/fumarate beta region)|interpro:IPR011167(Iron-dependent fumarate hydratase)|go:""GO:0004333""(fumarate hydratase activity)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR036660|refseq:YP_002348231.1|interpro:IPR051208"	"ensembl:ENSG00000147180.17(gene)|ensembl:ENST00000276123.7(transcript)|ensembl:ENST00000373165.7(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR006794(Zfx / Zfy transcription activation region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050826|mint:Q9Y462|rcsb pdb:9CJA|reactome:R-HSA-212436|refseq:NP_001317503.1|refseq:NP_068838.3|refseq:XP_005262243.1|refseq:XP_005262244.1|refseq:XP_005262245.1|refseq:XP_005262246.1|refseq:XP_011529326.1|refseq:XP_011529328.1|refseq:XP_016885294.1|refseq:XP_016885295.1|refseq:XP_016885296.1|refseq:XP_016885297.1|refseq:XP_016885298.1|efo:""Orphanet:777""|panther:PTHR16515(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+RE2hmq93gVFPvEwC+LKqnvbWt8632	rogid:+D8I1UK1AkHcgA4oKgk04+/Spvg9606	intact-crc:5E03EDD24B51FA88|rigid:EyP5d83Km6wNsXUGEgHxE/OJUME	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96JM2	uniprotkb:Q7ARD3	intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|ensembl:ENSP00000277225.5|intact:EBI-28975500	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849219|imex:IM-13779-5336	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000148143.13(gene)|ensembl:ENST00000277225.10(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006325""(chromatin organization)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050688|mint:Q96JM2|rcsb pdb:1X6F|refseq:NP_067047.4|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|efo:""Orphanet:502430""|panther:PTHR24403(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/16	rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:FB95E2269B47589D|rigid:mNqCkX683PE8gREZOpNtZYdbc1c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0K7	uniprotkb:Q8N720	intact:EBI-2849187|uniprotkb:Q74TN7	intact:EBI-625509|uniprotkb:Q8IV00|uniprotkb:Q8TA89|uniprotkb:Q96EZ3|uniprotkb:A4D291|uniprotkb:B4E3M4|uniprotkb:B7Z9Q9|intact:EBI-741438|uniprotkb:Q9BQ85|uniprotkb:D6W5T4|ensembl:ENSP00000252713.4|ensembl:ENSP00000377718.2|uniprotkb:A6NGD3	psi-mi:q8d0k7_yerpe(display_long)|uniprotkb:ldhA(gene name)|psi-mi:ldhA(display_short)|uniprotkb:y2004(locus name)	psi-mi:zn655_human(display_long)|uniprotkb:Vav-interacting Krueppel-like protein(gene name synonym)|uniprotkb:ZNF655(gene name)|psi-mi:ZNF655(display_short)|uniprotkb:VIK(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849192|imex:IM-13779-5335	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0051287""(NAD binding)|interpro:IPR036291"	"ensembl:ENSG00000197343.11(gene)|ensembl:ENST00000252713.9(transcript)|ensembl:ENST00000394163.2(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050826|mint:Q8N720|rcsb pdb:8PK6|reactome:R-HSA-212436|refseq:NP_001009960.1|refseq:NP_001077425.1|refseq:NP_001078835.1|refseq:NP_001078836.1|refseq:NP_001078837.1|refseq:NP_076966.1|refseq:NP_612503.1|refseq:NP_001009958.1|refseq:XP_016868092.1|refseq:XP_016868093.1|refseq:XP_016868095.1|refseq:XP_016868096.1|dip:DIP-34108N|panther:PTHR24377(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:NqOgptmC1Eq2xHlfaiWT6HnAdU4632	rogid:kz0A7h281PEWFM7dsPGoPyTAMgs9606	intact-crc:1F70DA1D110B4FAE|rigid:KNCx7AhRmDvPQFSryMyBxOM9xw0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKF8	uniprotkb:Q5T5D7	intact:EBI-2844579|uniprotkb:Q74RR5	intact:EBI-2849175|uniprotkb:Q2NKY4|ensembl:ENSP00000361784.3|ensembl:ENSP00000497154.1	psi-mi:q8ckf8_yerpe(display_long)|uniprotkb:y3542(locus name)	psi-mi:zn684_human(display_long)|uniprotkb:ZNF684(gene name)|psi-mi:ZNF684(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849180|imex:IM-13779-5332	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR037883	"refseq:XP_011538973.1|refseq:XP_011538974.1|refseq:XP_011538975.1|refseq:NP_689586.3|ensembl:ENSG00000117010.17(gene)|ensembl:ENST00000372699.8(transcript)|ensembl:ENST00000648542.1(transcript)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR050758|reactome:R-HSA-212436|refseq:XP_016855779.1|panther:PTHR24381(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bULfeL7EI8ZLrm+OLqILFkvARMg632	rogid:sW+A39LnFZQ3jXKQVZA5WBGryQs9606	intact-crc:F99F64154E546D0F|rigid:HwEJ39uLHZ6KBnBnFwnRNMlqW6w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6NX49	uniprotkb:Q8CZZ7	intact:EBI-2841978|uniprotkb:Q9UEX4|uniprotkb:A8K6J1|ensembl:ENSP00000269829.4|ensembl:ENSP00000469635.1|ensembl:ENSP00000510489.1	intact:EBI-2842831|uniprotkb:Q74W48	psi-mi:zn544_human(display_long)|uniprotkb:ZNF544(gene name)|psi-mi:ZNF544(display_short)	psi-mi:q8czz7_yerpe(display_long)|uniprotkb:recN(gene name)|psi-mi:recN(display_short)|uniprotkb:Recombination protein N(gene name synonym)|uniprotkb:YP_1051(locus name)|uniprotkb:y3075(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849212|imex:IM-13779-5334	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055295.2|refseq:NP_001307696.1|refseq:NP_001307698.1|refseq:NP_001307699.1|refseq:NP_001307700.1|refseq:NP_001307702.1|refseq:NP_001307705.1|refseq:NP_001307706.1|refseq:NP_001307709.1|refseq:NP_001307712.1|refseq:NP_001307714.1|refseq:NP_001307715.1|refseq:NP_001307720.1|ensembl:ENSG00000198131.15(gene)|ensembl:ENST00000269829.5(transcript)|ensembl:ENST00000596652.5(transcript)|ensembl:ENST00000687789.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q6NX49|reactome:R-HSA-212436|panther:PTHR24376(orthology-group)"	"interpro:IPR004604(DNA repair protein RecN)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7dcI2zjdUEKaTt0SX4w7ieh21Q49606	rogid:5D57QZRbHjtu2izZZ+54f7spmuk632	intact-crc:AF2E771F059AF246|rigid:cwj/N5dwxYYT7ovk0MToEVAdPMc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARK4	uniprotkb:Q8N720	intact:EBI-2849202|uniprotkb:Q74YZ8|uniprotkb:Q7ARG6|uniprotkb:Q7BT15|intact:EBI-2862232|uniprotkb:A0A3G5L2H4|uniprotkb:A0A1U8QNS3|uniprotkb:Q7CL24|uniprotkb:Q7CI35	intact:EBI-625509|uniprotkb:Q8IV00|uniprotkb:Q8TA89|uniprotkb:Q96EZ3|uniprotkb:A4D291|uniprotkb:B4E3M4|uniprotkb:B7Z9Q9|intact:EBI-741438|uniprotkb:Q9BQ85|uniprotkb:D6W5T4|ensembl:ENSP00000252713.4|ensembl:ENSP00000377718.2|uniprotkb:A6NGD3	psi-mi:q7ark4_yerpe(display_long)|uniprotkb:ypmt1.57c(gene name)|psi-mi:ypmt1.57c(display_short)|uniprotkb:Y0016(gene name synonym)|uniprotkb:DNA replication protein DnaC(gene name synonym)|uniprotkb:YPO0030(locus name)|uniprotkb:YPO0096(locus name)|uniprotkb:YPO0172(locus name)|uniprotkb:YPO0248(locus name)|uniprotkb:YPO0385(locus name)|uniprotkb:YPO0527(locus name)|uniprotkb:YPO0566(locus name)|uniprotkb:YPO0638(locus name)|uniprotkb:YPO0779(locus name)|uniprotkb:YPO0825(locus name)|uniprotkb:YPO0923(locus name)|uniprotkb:YPO1014(locus name)|uniprotkb:YPO1085(locus name)|uniprotkb:YPO1131(locus name)|uniprotkb:YPO1339(locus name)|uniprotkb:YPO1426(locus name)|uniprotkb:YPO1519(locus name)|uniprotkb:YPO1622(locus name)|uniprotkb:YPO1691(locus name)|uniprotkb:YPO1730(locus name)|uniprotkb:YPO1751(locus name)|uniprotkb:YPO1901(locus name)|uniprotkb:YPO2025(locus name)|uniprotkb:YPO2086(locus name)|uniprotkb:YPO2177(locus name)|uniprotkb:YPO2364(locus name)|uniprotkb:YPO2397(locus name)|uniprotkb:YPO2517(locus name)|uniprotkb:YPO2642(locus name)|uniprotkb:YPO2722(locus name)|uniprotkb:YPO2809(locus name)|uniprotkb:YPO2931(locus name)|uniprotkb:YPO3208(locus name)|uniprotkb:YPO3252(locus name)|uniprotkb:YPO3283(locus name)|uniprotkb:YPO3435(locus name)|uniprotkb:YPO3543(locus name)|uniprotkb:YPO3592(locus name)|uniprotkb:YPO3700(locus name)|uniprotkb:YPO3755(locus name)|uniprotkb:YPO3773(locus name)|uniprotkb:YPO4009(locus name)|uniprotkb:YPPCP1.02(locus name)|uniprotkb:YPMT1.02(locus name)|uniprotkb:YPMT1.57c(locus name)	psi-mi:zn655_human(display_long)|uniprotkb:Vav-interacting Krueppel-like protein(gene name synonym)|uniprotkb:ZNF655(gene name)|psi-mi:ZNF655(display_short)|uniprotkb:VIK(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849199|imex:IM-13779-5333	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_001317493.1|refseq:NP_395228.1|refseq:NP_395337.2|refseq:NP_395401.1|refseq:NP_857912.1|refseq:YP_094026.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002611(IstB-like ATP-binding protein)|interpro:IPR028350|interpro:IPR027417|interpro:IPR047661|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006260""(DNA replication)|go:""GO:0006269""(DNA replication, synthesis of primer)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:1990077""(primosome complex)|refseq:YP_002345126.1|refseq:YP_002345187.1|refseq:YP_002345257.1|refseq:YP_002345329.1|refseq:YP_002345462.1|refseq:YP_002345600.1|refseq:YP_002345637.1|refseq:YP_002345705.1|refseq:YP_002345835.1|refseq:YP_002345879.1|refseq:YP_002345971.1|refseq:YP_002346057.1|refseq:YP_002346128.1|refseq:YP_002346173.1|refseq:YP_002346363.1|refseq:YP_002346449.1|refseq:YP_002346535.1|refseq:YP_002346633.1|refseq:YP_002346694.1|refseq:YP_002346731.1|refseq:YP_002346751.1|refseq:YP_002346891.1|refseq:YP_002347009.1|refseq:YP_002347067.1|refseq:YP_002347151.1|refseq:YP_002347331.1|refseq:YP_002347363.1|refseq:YP_002347481.1|refseq:YP_002347595.1|refseq:YP_002347669.1|refseq:YP_002347750.1|refseq:YP_002347861.1|refseq:YP_002348111.1|refseq:YP_002348153.1|refseq:YP_002348182.1|refseq:YP_002348327.1|refseq:YP_002348431.1|refseq:YP_002348477.1|refseq:YP_002348582.1|refseq:YP_002348635.1|refseq:YP_002348651.1|refseq:YP_002348876.1|panther:PTHR30050(orthology-group)"	"ensembl:ENSG00000197343.11(gene)|ensembl:ENST00000252713.9(transcript)|ensembl:ENST00000394163.2(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:2000134""(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050826|mint:Q8N720|rcsb pdb:8PK6|reactome:R-HSA-212436|refseq:NP_001009960.1|refseq:NP_001077425.1|refseq:NP_001078835.1|refseq:NP_001078836.1|refseq:NP_001078837.1|refseq:NP_076966.1|refseq:NP_612503.1|refseq:NP_001009958.1|refseq:XP_016868092.1|refseq:XP_016868093.1|refseq:XP_016868095.1|refseq:XP_016868096.1|dip:DIP-34108N|panther:PTHR24377(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:yqskl8o49hYONtduM+rZmKno4uU632	rogid:kz0A7h281PEWFM7dsPGoPyTAMgs9606	intact-crc:D7956451CEEE59A2|rigid:UBrd4pMgDsLClTyCxfnAKkuUm2A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60281	uniprotkb:Q8D0V0	intact:EBI-1224010|uniprotkb:Q9H8G3|uniprotkb:Q9H8J4|uniprotkb:Q5W0B2|uniprotkb:Q7Z3L7|ensembl:ENSP00000358590.3|intact:EBI-28971048	intact:EBI-2849272	psi-mi:zn292_human(display_long)|uniprotkb:ZNF292(gene name)|psi-mi:ZNF292(display_short)|uniprotkb:KIAA0530(gene name synonym)	psi-mi:q8d0v0_yerpe(display_long)|uniprotkb:fadL(gene name)|psi-mi:fadL(display_short)|uniprotkb:Outer membrane FadL protein(gene name synonym)|uniprotkb:Outer membrane flp protein(gene name synonym)|uniprotkb:y1577(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849276|imex:IM-13779-5338	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055836.1|ensembl:ENSG00000188994.14(gene)|ensembl:ENST00000369577.8(transcript)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR052251|mint:O60281|rcsb pdb:1X3C|rcsb pdb:7N2D|panther:PTHR15507(orthology-group)"	"interpro:IPR005017(Membrane protein involved in aromatic hydrocarbon degradation)|go:""GO:0006869""(lipid transport)|go:""GO:0009279""(cell outer membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4Ss6SyxGv1bSjSBhSjquUKutB349606	rogid:t3ttYDBykbAjdOq/JpJE2QGeyvk632	intact-crc:DD84348E039C0B83|rigid:HpShMZWQ+sKIyqYFCCTA4ReWZOk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N895	uniprotkb:Q8D1J6	intact:EBI-2813661|uniprotkb:Q7RTV4|uniprotkb:Q5HYI9|ensembl:ENSP00000313158.5	intact:EBI-2848106|uniprotkb:Q74R63	psi-mi:zn366_human(display_long)|uniprotkb:ZNF366(gene name)|psi-mi:ZNF366(display_short)|uniprotkb:Dendritic cell-specific transcript protein(gene name synonym)	psi-mi:q8d1j6_yerpe(display_long)|uniprotkb:cof3(gene name)|psi-mi:cof3(display_short)|uniprotkb:YP_3219(locus name)|uniprotkb:y0401(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849242|imex:IM-13779-5337	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_689838.1|ensembl:ENSG00000178175.12(gene)|ensembl:ENST00000318442.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0030331""(nuclear estrogen receptor binding)|go:""GO:0033147""(negative regulation of intracellular estrogen receptor signaling pathway)|go:""GO:0043627""(response to estrogen)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050636|panther:PTHR24390(orthology-group)"	"interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR000150(Cof protein)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0016791""(phosphatase activity)|interpro:IPR036412|interpro:IPR023214"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eE4EW7+MMZfDglVayxF2rOZpFDE9606	rogid:x7t5HiadL8tDg8jpwvxHHgrzBZE632	intact-crc:2130243863EFDECE|rigid:/LLXYnJrQJdrZf9ZMtOOBkO5v1o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NRM2	uniprotkb:Q8D0V8	intact:EBI-949305|uniprotkb:Q75MZ2|uniprotkb:Q75MZ3|uniprotkb:Q8WY14|ensembl:ENSP00000354501.3	intact:EBI-2843099	psi-mi:zn277_human(display_long)|uniprotkb:ZNF277(gene name)|psi-mi:ZNF277(display_short)|uniprotkb:ZNF277P(gene name synonym)|uniprotkb:NRIF4(gene name synonym)|uniprotkb:Nuclear receptor-interacting factor 4(gene name synonym)	psi-mi:q8d0v8_yerpe(display_long)|uniprotkb:y1519(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849283|imex:IM-13779-5339	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_068834.2|ensembl:ENSG00000198839.10(gene)|ensembl:ENST00000361822.8(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:2000772""(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|panther:PTHR13267(orthology-group)"	"interpro:IPR011888(Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR019546|interpro:IPR027467|go:""GO:0009389""(dimethyl sulfoxide reductase activity)|go:""GO:0030151""(molybdenum ion binding)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR050612"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LH60QmqqTZD5rgMq1hXWbyCO09s9606	rogid:CcHr0E9LratmjBgXeGfmzvxLVPo632	intact-crc:03AFE4F7EC924DF2|rigid:EZhZEhS3RPqYCGrOJG6J7Os+F7I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0X2	uniprotkb:P59923	intact:EBI-2849235	intact:EBI-2849229|uniprotkb:Q3MJD1|ensembl:ENSP00000379387.2|ensembl:ENSP00000413073.2	psi-mi:q8d0x2_yerpe(display_long)|uniprotkb:y1457(locus name)	psi-mi:zn445_human(display_long)|uniprotkb:ZNF445(gene name)|psi-mi:ZNF445(display_short)|uniprotkb:ZKSCAN15(gene name synonym)|uniprotkb:ZNF168(gene name synonym)|uniprotkb:Zinc finger protein 168(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 15(gene name synonym)|uniprotkb:ZFP445(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849226|imex:IM-13779-5341	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR006314(Dyp-type peroxidase)|go:""GO:0004601""(peroxidase activity)|go:""GO:0020037""(heme binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR048327|interpro:IPR048328"	"refseq:XP_011531976.1|refseq:NP_852466.1|refseq:XP_005265159.1|ensembl:ENSG00000185219.18(gene)|ensembl:ENST00000396077.8(transcript)|ensembl:ENST00000425708.6(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0010385""(double-stranded methylated DNA binding)|go:""GO:0044027""(negative regulation of gene expression via chromosomal CpG island methylation)|go:""GO:0044726""(epigenetic programing of female pronucleus)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:P59923|reactome:R-HSA-212436|panther:PTHR24376(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6W/ykCxa45tyhuiei7YsTgIaGyU632	rogid:yTfAKMo3tO7walE9ol17nTIeuw89606	intact-crc:C63988EC5B8CC08A|rigid:4TLJuKtVtlKWSgYTW4rY6UoMHjs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5VUA4	uniprotkb:Q8ZHG8	intact:EBI-2849257|uniprotkb:Q8NEM6|uniprotkb:Q9UNU8|uniprotkb:Q4G0E4|uniprotkb:O94796|uniprotkb:Q9Y2W9|ensembl:ENSP00000354964.2|intact:EBI-28976662	intact:EBI-2849252|uniprotkb:Q0WIB1	psi-mi:zn318_human(display_long)|uniprotkb:ZNF318(gene name)|psi-mi:ZNF318(display_short)|uniprotkb:Endocrine regulatory protein(gene name synonym)|uniprotkb:HRIHFB2436(orf name)	psi-mi:spea_yerpe(display_long)|uniprotkb:speA(gene name)|psi-mi:speA(display_short)|uniprotkb:YPO0929(locus name)|uniprotkb:y3313(locus name)|uniprotkb:YP_3513(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849249|imex:IM-13779-5340	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011512754.1|ensembl:ENSG00000171467.16(gene)|ensembl:ENST00000361428.3(transcript)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0051321""(meiotic cell cycle)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR055309|mint:Q5VUA4|refseq:NP_055160.2|panther:PTHR15577(orthology-group)"	"interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR002985(Arginine decarboxylase)|interpro:IPR022657|interpro:IPR022644|interpro:IPR022653|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|interpro:IPR029066|interpro:IPR040634|go:""GO:0006527""(arginine catabolic process)|go:""GO:0008295""(spermidine biosynthetic process)|go:""GO:0008792""(arginine decarboxylase activity)|go:""GO:0033388""(putrescine biosynthetic process from arginine)|go:""GO:0046872""(metal ion binding)|interpro:IPR041128|refseq:WP_002209969.1|refseq:YP_002345977.1|panther:PTHR43295(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HqHWYB1s5uaauSljuYFDb3/6XB49606	rogid:WJK/NuC1y1WJhbzgBDwly+QaYwA632	intact-crc:7D6F72E223C96E56|rigid:TtD+3xqxxg6wAXD6agCWlqyEuZA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43670	uniprotkb:Q8ZII0	intact:EBI-2513125|uniprotkb:A8K6Y6|uniprotkb:Q96HW5|uniprotkb:Q9BUQ7|uniprotkb:Q53XS9|ensembl:ENSP00000322777.6|uniprotkb:E1P661|uniprotkb:E1P662|uniprotkb:E1P660	intact:EBI-2845275|uniprotkb:Q0WJE7	psi-mi:zn207_human(display_long)|uniprotkb:ZNF207(gene name)|psi-mi:ZNF207(display_short)|uniprotkb:BUGZ(gene name synonym)|uniprotkb:Zinc finger protein 207(gene name synonym)	psi-mi:rapa_yerpe(display_long)|uniprotkb:rapA(gene name)|psi-mi:rapA(display_short)|uniprotkb:hepA(gene name synonym)|uniprotkb:YPO0517(locus name)|uniprotkb:y3656(locus name)|uniprotkb:YP_3662(locus name)|uniprotkb:ATP-dependent helicase HepA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849309|imex:IM-13779-5343	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001027464.1|refseq:NP_001091977.1|refseq:NP_003448.1|ensembl:ENSG00000010244.19(gene)|ensembl:ENST00000321233.10(transcript)|go:""GO:0000070""(mitotic sister chromatid segregation)|go:""GO:0000776""(kinetochore)|go:""GO:0001578""(microtubule bundle formation)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005874""(microtubule)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008017""(microtubule binding)|go:""GO:0008201""(heparin binding)|go:""GO:0008608""(attachment of spindle microtubules to kinetochore)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0046872""(metal ion binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051301""(cell division)|go:""GO:0051983""(regulation of chromosome segregation)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:1990047""(spindle matrix)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:O43670|refseq:XP_016880508.1|panther:PTHR23215(orthology-group)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR023949|interpro:IPR022737|interpro:IPR000330(SNF2-related)|interpro:IPR040765|interpro:IPR040766|interpro:IPR027417|refseq:WP_002220588.1|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016817""(hydrolase activity, acting on acid anhydrides)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0140750""(nucleosome array spacer activity)|interpro:IPR038718|refseq:YP_002345591.1|interpro:IPR049730|panther:PTHR10799(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yXD8JFABrqlAoAAPPECwHsUmFNc9606	rogid:aLthHtAzTIsYwrCvth6qDQS+yVs632	intact-crc:EB153E67B928C7B6|rigid:+A3kBc/c2shfzo40mC0dvoaJOX4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H0Q2	uniprotkb:O43670	intact:EBI-2849316|uniprotkb:Q74T97|uniprotkb:A0A0H2W5H0|uniprotkb:A0A380SBC9|uniprotkb:Q7CJ44|uniprotkb:A0A384KC05	intact:EBI-2513125|uniprotkb:A8K6Y6|uniprotkb:Q96HW5|uniprotkb:Q9BUQ7|uniprotkb:Q53XS9|ensembl:ENSP00000322777.6|uniprotkb:E1P661|uniprotkb:E1P662|uniprotkb:E1P660	psi-mi:a0a2u2h0q2_yerpe(display_long)|uniprotkb:YPO2473(locus name)	psi-mi:zn207_human(display_long)|uniprotkb:ZNF207(gene name)|psi-mi:ZNF207(display_short)|uniprotkb:BUGZ(gene name synonym)|uniprotkb:Zinc finger protein 207(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849320|imex:IM-13779-5344	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR015045(Protein of unknown function DUF1861)|interpro:IPR023296|refseq:WP_002213840.1|refseq:YP_002347437.1	"refseq:NP_001027464.1|refseq:NP_001091977.1|refseq:NP_003448.1|ensembl:ENSG00000010244.19(gene)|ensembl:ENST00000321233.10(transcript)|go:""GO:0000070""(mitotic sister chromatid segregation)|go:""GO:0000776""(kinetochore)|go:""GO:0001578""(microtubule bundle formation)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005819""(spindle)|go:""GO:0005874""(microtubule)|go:""GO:0007094""(mitotic spindle assembly checkpoint signaling)|go:""GO:0008017""(microtubule binding)|go:""GO:0008201""(heparin binding)|go:""GO:0008608""(attachment of spindle microtubules to kinetochore)|go:""GO:0046785""(microtubule polymerization)|go:""GO:0046872""(metal ion binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0051301""(cell division)|go:""GO:0051983""(regulation of chromosome segregation)|go:""GO:0090307""(mitotic spindle assembly)|go:""GO:1990047""(spindle matrix)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:O43670|refseq:XP_016880508.1|panther:PTHR23215(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:O/NA0dkts3mvJMI8kSLzsoLX53I632	rogid:yXD8JFABrqlAoAAPPECwHsUmFNc9606	intact-crc:7F734EBB4AD0CE4C|rigid:osJIUtA3tyQAmfxKRJZXAERh6L0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P52747	uniprotkb:Q8CKA6	intact:EBI-2849334|uniprotkb:O75559|uniprotkb:A8K518|uniprotkb:Q8WUK9|uniprotkb:B4DLY5|uniprotkb:E7ER34|ensembl:ENSP00000379847.2	intact:EBI-2849330|uniprotkb:Q74QW6	psi-mi:zn143_human(display_long)|uniprotkb:ZNF143(gene name)|psi-mi:ZNF143(display_short)|uniprotkb:SBF(gene name synonym)|uniprotkb:STAF(gene name synonym)|uniprotkb:SPH-binding factor(gene name synonym)|uniprotkb:Selenocysteine tRNA gene transcription-activating factor(gene name synonym)	psi-mi:q8cka6_yerpe(display_long)|uniprotkb:y3854(locus name)|uniprotkb:YP_3338(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849327|imex:IM-13779-5346	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269585.1|refseq:NP_001269586.1|refseq:XP_011518651.1|refseq:NP_003433.3|refseq:XP_016873743.1|refseq:XP_016873744.1|ensembl:ENSG00000166478.10(gene)|ensembl:ENST00000396602.7(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006359""(regulation of transcription by RNA polymerase III)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0045945""(positive regulation of transcription by RNA polymerase III)|go:""GO:0046872""(metal ion binding)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:1905382""(positive regulation of snRNA transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P52747|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|panther:PTHR24388(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UE8tZG7jHDlKiOlSfYC+TqImOX09606	rogid:pmcmhu84S4iT19THpCVa9iBmwsg632	intact-crc:F47275A50253D1CA|rigid:ZwIbby+UkkGMOsB+EYsyzACoxgI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H357	uniprotkb:Q9NRM2	intact:EBI-2849293|uniprotkb:Q74SU9|uniprotkb:Q0WDM6|uniprotkb:A0A3N4B135|uniprotkb:Q7CJS6|uniprotkb:A0A384L590	intact:EBI-949305|uniprotkb:Q75MZ2|uniprotkb:Q75MZ3|uniprotkb:Q8WY14|ensembl:ENSP00000354501.3	psi-mi:a0a2u2h357_yerpe(display_long)|uniprotkb:YPO2663(locus name)	psi-mi:zn277_human(display_long)|uniprotkb:ZNF277(gene name)|psi-mi:ZNF277(display_short)|uniprotkb:ZNF277P(gene name synonym)|uniprotkb:NRIF4(gene name synonym)|uniprotkb:Nuclear receptor-interacting factor 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849290|imex:IM-13779-5342	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_002212225.1|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_002347612.1|interpro:IPR050388"	"refseq:NP_068834.2|ensembl:ENSG00000198839.10(gene)|ensembl:ENST00000361822.8(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:2000772""(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|panther:PTHR13267(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zrHDXTLLjUhMVDoxmosKV0sLQ0Q632	rogid:LH60QmqqTZD5rgMq1hXWbyCO09s9606	intact-crc:7C12A02169111452|rigid:XHj0Zxmt8y3vLGuyaO8fOixxXWI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NRM2	uniprotkb:Q7ARD3	intact:EBI-949305|uniprotkb:Q75MZ2|uniprotkb:Q75MZ3|uniprotkb:Q8WY14|ensembl:ENSP00000354501.3	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:zn277_human(display_long)|uniprotkb:ZNF277(gene name)|psi-mi:ZNF277(display_short)|uniprotkb:ZNF277P(gene name synonym)|uniprotkb:NRIF4(gene name synonym)|uniprotkb:Nuclear receptor-interacting factor 4(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849302|imex:IM-13779-5345	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_068834.2|ensembl:ENSG00000198839.10(gene)|ensembl:ENST00000361822.8(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0046872""(metal ion binding)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:2000772""(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|panther:PTHR13267(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LH60QmqqTZD5rgMq1hXWbyCO09s9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:4EB85ABB3195D63C|rigid:5p3dkzVchPRR/QCY33hTzVKBAQc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IYN0	uniprotkb:Q8CZQ3	intact:EBI-2849363|uniprotkb:Q7M4M0|ensembl:ENSP00000351042.5|ensembl:ENSP00000483779.1	intact:EBI-2849368|uniprotkb:Q74Q61	psi-mi:zn100_human(display_long)|uniprotkb:ZNF100(gene name)|psi-mi:ZNF100(display_short)	psi-mi:q8czq3_yerpe(display_long)|uniprotkb:ilvI(gene name)|psi-mi:ilvI(display_short)|uniprotkb:y3640(locus name)|uniprotkb:YP_3646(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849373|imex:IM-13779-5347	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_775802.2|ensembl:ENSG00000197020.12(gene)|ensembl:ENSG00000274746.4(gene)|ensembl:ENST00000358296.11(transcript)|ensembl:ENST00000614218.4(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|panther:PTHR24384(orthology-group)"	"interpro:IPR039368|interpro:IPR012846(Acetolactate synthase, large subunit, biosynthetic)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR029035|interpro:IPR029061|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003984""(acetolactate synthase activity)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR045229"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qzbCduTmyD+IY7/DkhtWDECD/VQ9606	rogid:HjawDXJtJf287797Q9KXxlU93ng632	intact-crc:F0111E5B4ACB046E|rigid:4edjHqiIFBIqKri2PkM5v9iVfEU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UBW7	uniprotkb:Q8ZAC2	intact:EBI-2797576|ensembl:ENSP00000372324.2|ensembl:ENSP00000372327.2|ensembl:ENSP00000479904.1|intact:EBI-25598824|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898	intact:EBI-2840531|uniprotkb:Q0WAC4	psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short)	psi-mi:ilvc_yerpe(display_long)|uniprotkb:ilvC(gene name)|psi-mi:ilvC(display_short)|uniprotkb:Acetohydroxy-acid isomeroreductase(gene name synonym)|uniprotkb:Alpha-keto-beta-hydroxylacyl reductoisomerase(gene name synonym)|uniprotkb:Ketol-acid reductoisomerase type 2(gene name synonym)|uniprotkb:Ketol-acid reductoisomerase type II(gene name synonym)|uniprotkb:YPO3888(locus name)|uniprotkb:YP_3158(locus name)|uniprotkb:y0345(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849392|imex:IM-13779-5350	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000121741.17(gene)|ensembl:ENST00000382871.3(transcript)|ensembl:ENST00000382874.6(transcript)|ensembl:ENST00000610343.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016605""(PML body)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|interpro:IPR051284|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|refseq:XP_005266577.1|refseq:XP_011533526.1|refseq:XP_016876218.1|efo:""Orphanet:528084""|panther:PTHR45736(orthology-group)"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013023(Acetohydroxy acid isomeroreductase)|interpro:IPR000506(Acetohydroxy acid isomeroreductase C-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR013116(Acetohydroxy acid isomeroreductase, catalytic)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004455""(ketol-acid reductoisomerase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|refseq:WP_002212007.1|refseq:YP_002348764.1|interpro:IPR036291|panther:PTHR21371(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606	rogid:YXB9ATGj7Tcv7U9t7G60g2fFs+8632	intact-crc:DBCB2F3DDF3B0EBD|rigid:0h46SV2TMqvycI5QciXdVcLQ+RM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P52739	uniprotkb:Q8D1Q7	intact:EBI-2849346|uniprotkb:B4DRL3|uniprotkb:Q6PIF0|ensembl:ENSP00000426504.1|ensembl:ENSP00000507111.1	intact:EBI-2849355|uniprotkb:Q74PQ6	psi-mi:zn131_human(display_long)|uniprotkb:ZNF131(gene name)|psi-mi:ZNF131(display_short)	psi-mi:q8d1q7_yerpe(display_long)|uniprotkb:YP_3835(locus name)|uniprotkb:lptA(gene name)|psi-mi:lptA(display_short)|uniprotkb:y0152(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849352|imex:IM-13779-5349	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_005248420.1|refseq:NP_001284477.1|ensembl:ENSG00000172262.12(gene)|ensembl:ENST00000509156.5(transcript)|ensembl:ENST00000682664.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0005654""(nucleoplasm)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0046872""(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P52739|reactome:R-HSA-3899300|refseq:NP_001317636.1|refseq:NP_001317637.1|refseq:NP_001317641.1|refseq:NP_001317643.1|refseq:NP_001317646.1|refseq:XP_016865319.1|refseq:NP_001317635.1|refseq:NP_001317640.1|refseq:NP_001317642.1|refseq:NP_001317644.1|refseq:NP_003423.1|refseq:XP_016865323.1|refseq:XP_016865327.1|panther:PTHR24399(orthology-group)"	"interpro:IPR014340(Cell envelope biogenesis YhbN)|interpro:IPR005653(OstA-like protein)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0015920""(lipopolysaccharide transport)|go:""GO:0042597""(periplasmic space)|go:""GO:0043165""(Gram-negative-bacterium-type cell outer membrane assembly)|interpro:IPR052037"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lOpLfe/zMQVEvjp6wFCITqy3zms9606	rogid:pIQ591Q2w8n+nGze7YtZ1os7wQ4632	intact-crc:2058A1E1752BB63A|rigid:fk3G+EbSUwrgBHFLwPHUo/TIi7Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BA87	uniprotkb:Q9UBW7	intact:EBI-2849383|uniprotkb:Q74PH8|uniprotkb:A0A0H2W8Y4|uniprotkb:Q7CL39|uniprotkb:A0A384L9C4	intact:EBI-2797576|ensembl:ENSP00000372324.2|ensembl:ENSP00000372327.2|ensembl:ENSP00000479904.1|intact:EBI-25598824|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898	psi-mi:a0a3n4ba87_yerpe(display_long)|uniprotkb:ISU59_19965(orf name)|uniprotkb:YPO3618(locus name)	psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849380|imex:IM-13779-5348	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004104(Oxidoreductase, C-terminal)|interpro:IPR000683(Oxidoreductase, N-terminal)|refseq:WP_002210025.1|go:""GO:0000166""(nucleotide binding)|go:""GO:0005829""(cytosol)|go:""GO:0017000""(antibiotic biosynthetic process)|go:""GO:0102497""(""scyllo-inositol dehydrogenase (NADP+) activity"")|interpro:IPR036291|refseq:YP_002348503.1|interpro:IPR051317|panther:PTHR43708(orthology-group)"	"ensembl:ENSG00000121741.17(gene)|ensembl:ENST00000382871.3(transcript)|ensembl:ENST00000382874.6(transcript)|ensembl:ENST00000610343.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016605""(PML body)|go:""GO:0031624""(ubiquitin conjugating enzyme binding)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|interpro:IPR051284|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|refseq:XP_005266577.1|refseq:XP_011533526.1|refseq:XP_016876218.1|efo:""Orphanet:528084""|panther:PTHR45736(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oAKjFkWV9yeIL0iPB/h3xOcZxZw632	rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606	intact-crc:FCBCF1CB46408467|rigid:2V1ecUn35x2z6ARQubEhGm5gwfA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARH3	uniprotkb:Q9ULJ6	intact:EBI-2849426|uniprotkb:A0A384KLR8|uniprotkb:O68711|uniprotkb:Q74YV0|uniprotkb:A0A0H2W092|uniprotkb:A0A2U2GVE2	intact:EBI-308362|uniprotkb:Q7Z7E6|uniprotkb:Q5JSH9|ensembl:ENSP00000334474.5	psi-mi:q7arh3_yerpe(display_long)|uniprotkb:tnpA(gene name)|psi-mi:tnpA(display_short)|uniprotkb:YPCD1.90c(locus name)	psi-mi:zmiz1_human(display_long)|uniprotkb:ZMIZ1(gene name)|psi-mi:ZMIZ1(display_short)|uniprotkb:KIAA1224(gene name synonym)|uniprotkb:ZIMP10(gene name synonym)|uniprotkb:RAI17(gene name synonym)|uniprotkb:Retinoic acid-induced protein 17(gene name synonym)|uniprotkb:PIAS-like protein Zimp10(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849430|imex:IM-13779-5352	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_857769.1|interpro:IPR002513(Transposase, Tn3)|refseq:NP_395219.1|interpro:IPR025296|interpro:IPR047653|refseq:WP_002213256.1|go:""GO:0003677""(DNA binding)|go:""GO:0004803""(transposase activity)|go:""GO:0006313""(DNA transposition)"	"ensembl:ENSG00000108175.19(gene)|ensembl:ENST00000334512.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007296""(vitellogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016925""(protein sumoylation)|go:""GO:0021852""(pyramidal neuron migration to cerebral cortex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048589""(developmental growth)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0090398""(cellular senescence)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040797|mint:Q9ULJ6|rcsb pdb:5AIZ|refseq:NP_065071.1|refseq:XP_011538282.1|refseq:XP_016871931.1|efo:""Orphanet:528084""|panther:PTHR10782(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:00nBYkSaVEOjkb6Bm6Lk/llhQRc632	rogid:gqMqBRe+muLdsN5jD0SGo6r88a09606	intact-crc:911267BAE503E966|rigid:o3zPq7DtOPFKoGQSD90s8L3VO+4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULJ6	uniprotkb:A0A3N4B6K1	intact:EBI-308362|uniprotkb:Q7Z7E6|uniprotkb:Q5JSH9|ensembl:ENSP00000334474.5	intact:EBI-2841967|uniprotkb:Q7CHV2|uniprotkb:Q0WG31	psi-mi:zmiz1_human(display_long)|uniprotkb:ZMIZ1(gene name)|psi-mi:ZMIZ1(display_short)|uniprotkb:KIAA1224(gene name synonym)|uniprotkb:ZIMP10(gene name synonym)|uniprotkb:RAI17(gene name synonym)|uniprotkb:Retinoic acid-induced protein 17(gene name synonym)|uniprotkb:PIAS-like protein Zimp10(gene name synonym)	psi-mi:a0a3n4b6k1_yerpe(display_long)|uniprotkb:EIIAB-Man(gene name synonym)|uniprotkb:gptB(gene name)|psi-mi:gptB(display_short)|uniprotkb:EIII-Man(gene name synonym)|uniprotkb:manX(gene name synonym)|uniprotkb:ptsL(gene name synonym)|uniprotkb:YPO1758(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849406|imex:IM-13779-5351	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108175.19(gene)|ensembl:ENST00000334512.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007296""(vitellogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016925""(protein sumoylation)|go:""GO:0021852""(pyramidal neuron migration to cerebral cortex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048589""(developmental growth)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0090398""(cellular senescence)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040797|mint:Q9ULJ6|rcsb pdb:5AIZ|refseq:NP_065071.1|refseq:XP_011538282.1|refseq:XP_016871931.1|efo:""Orphanet:528084""|panther:PTHR10782(orthology-group)"	"interpro:IPR004701(Phosphotransferase system, fructose subfamily IIA component)|interpro:IPR013789(Phosphotransferase system, fructose subfamily IIA component, subgroup)|interpro:IPR004720(Phosphotransferase system, sorbose subfamily IIB component)|interpro:IPR018455|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|interpro:IPR033887|interpro:IPR036662|interpro:IPR036667|refseq:WP_002211069.1|refseq:YP_002346757.1|interpro:IPR051471|panther:PTHR33799(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gqMqBRe+muLdsN5jD0SGo6r88a09606	rogid:6EMnus36OolbaozHpfdN+4jAtF0632	intact-crc:8F06A777ACC8F2ED|rigid:RBXYYB91kFS8gJu+UsWLIxS7yVw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULJ6	uniprotkb:Q8ZHF1	intact:EBI-308362|uniprotkb:Q7Z7E6|uniprotkb:Q5JSH9|ensembl:ENSP00000334474.5	intact:EBI-2849437|uniprotkb:Q0WI93	psi-mi:zmiz1_human(display_long)|uniprotkb:ZMIZ1(gene name)|psi-mi:ZMIZ1(display_short)|uniprotkb:KIAA1224(gene name synonym)|uniprotkb:ZIMP10(gene name synonym)|uniprotkb:RAI17(gene name synonym)|uniprotkb:Retinoic acid-induced protein 17(gene name synonym)|uniprotkb:PIAS-like protein Zimp10(gene name synonym)	psi-mi:glsa1_yerpe(display_long)|uniprotkb:glsA1(gene name)|psi-mi:glsA1(display_short)|uniprotkb:YPO0949(locus name)|uniprotkb:y3336(locus name)|uniprotkb:YP_3492(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849442|imex:IM-13779-5353	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108175.19(gene)|ensembl:ENST00000334512.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007296""(vitellogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016925""(protein sumoylation)|go:""GO:0021852""(pyramidal neuron migration to cerebral cortex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048589""(developmental growth)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0090398""(cellular senescence)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040797|mint:Q9ULJ6|rcsb pdb:5AIZ|refseq:NP_065071.1|refseq:XP_011538282.1|refseq:XP_016871931.1|efo:""Orphanet:528084""|panther:PTHR10782(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|refseq:WP_002209989.1|go:""GO:0004359""(glutaminase activity)|go:""GO:0006537""(glutamate biosynthetic process)|go:""GO:0006543""(glutamine catabolic process)|refseq:YP_002345995.1|panther:PTHR12544(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gqMqBRe+muLdsN5jD0SGo6r88a09606	rogid:RXiLjz5WJJYlM97YSg1neu4h+FA632	intact-crc:9150F2483AB93DFA|rigid:TghtE5/7+RgvZjJJVReVBNGxPG4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULJ6	uniprotkb:A0A3N4BT88	intact:EBI-308362|uniprotkb:Q7Z7E6|uniprotkb:Q5JSH9|ensembl:ENSP00000334474.5	intact:EBI-2849413|uniprotkb:Q74QQ0|uniprotkb:A0A5P8YCG8|uniprotkb:Q7CGN1|uniprotkb:A0A0H2W7V7	psi-mi:zmiz1_human(display_long)|uniprotkb:ZMIZ1(gene name)|psi-mi:ZMIZ1(display_short)|uniprotkb:KIAA1224(gene name synonym)|uniprotkb:ZIMP10(gene name synonym)|uniprotkb:RAI17(gene name synonym)|uniprotkb:Retinoic acid-induced protein 17(gene name synonym)|uniprotkb:PIAS-like protein Zimp10(gene name synonym)	psi-mi:a0a3n4bt88_yerpe(display_long)|uniprotkb:ISU56_05775(orf name)|uniprotkb:YPO1001(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849419|imex:IM-13779-5354	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108175.19(gene)|ensembl:ENST00000334512.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007296""(vitellogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016925""(protein sumoylation)|go:""GO:0021852""(pyramidal neuron migration to cerebral cortex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048589""(developmental growth)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0090398""(cellular senescence)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040797|mint:Q9ULJ6|rcsb pdb:5AIZ|refseq:NP_065071.1|refseq:XP_011538282.1|refseq:XP_016871931.1|efo:""Orphanet:528084""|panther:PTHR10782(orthology-group)"	"interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR004764(Hydrophobe/amphiphile efflux-1 HAE1)|interpro:IPR027463|go:""GO:0005886""(plasma membrane)|go:""GO:0015562""(efflux transmembrane transporter activity)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:WP_002211642.1|refseq:YP_002346046.1|panther:PTHR32063(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gqMqBRe+muLdsN5jD0SGo6r88a09606	rogid:hK6YBBZ+84LaijrPPqfrUZOmu5w632	intact-crc:EE277BE5C95F02A3|rigid:cOomQLDQAz6688MVTwvJlnVlpY8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9ULJ6	uniprotkb:Q8ZES0	intact:EBI-308362|uniprotkb:Q7Z7E6|uniprotkb:Q5JSH9|ensembl:ENSP00000334474.5	intact:EBI-2845458|uniprotkb:Q0WF73	psi-mi:zmiz1_human(display_long)|uniprotkb:ZMIZ1(gene name)|psi-mi:ZMIZ1(display_short)|uniprotkb:KIAA1224(gene name synonym)|uniprotkb:ZIMP10(gene name synonym)|uniprotkb:RAI17(gene name synonym)|uniprotkb:Retinoic acid-induced protein 17(gene name synonym)|uniprotkb:PIAS-like protein Zimp10(gene name synonym)	psi-mi:y2083_yerpe(display_long)|uniprotkb:YPO2083(locus name)|uniprotkb:y2228(locus name)|uniprotkb:YP_1926(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849399|imex:IM-13779-5355	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108175.19(gene)|ensembl:ENST00000334512.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007296""(vitellogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016925""(protein sumoylation)|go:""GO:0021852""(pyramidal neuron migration to cerebral cortex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048589""(developmental growth)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0090398""(cellular senescence)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040797|mint:Q9ULJ6|rcsb pdb:5AIZ|refseq:NP_065071.1|refseq:XP_011538282.1|refseq:XP_016871931.1|efo:""Orphanet:528084""|panther:PTHR10782(orthology-group)"	interpro:IPR008228(Uncharacterised conserved protein UCP006173)|interpro:IPR005358(Protein of unknown function UPF0153)|refseq:WP_002211739.1|refseq:YP_002347065.1|panther:PTHR37421(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gqMqBRe+muLdsN5jD0SGo6r88a09606	rogid:p1yW4rWt+CvstvpxbwtZ4Y1jXAU632	intact-crc:4AB6CF483AE121BE|rigid:MmDRQlgWyihvc2aNCarXCO2tgj0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZDA6	uniprotkb:Q9ULJ6	intact:EBI-2843773|uniprotkb:Q0WDK8	intact:EBI-308362|uniprotkb:Q7Z7E6|uniprotkb:Q5JSH9|ensembl:ENSP00000334474.5	psi-mi:chbg_yerpe(display_long)|uniprotkb:chbG(gene name)|psi-mi:chbG(display_short)|uniprotkb:Chitin disaccharide deacetylase(gene name synonym)|uniprotkb:Chitobiose deacetylase(gene name synonym)|uniprotkb:Chitobiose-6P deacetylase(gene name synonym)|uniprotkb:Chitotriose deacetylase(gene name synonym)|uniprotkb:Chitotriose-6P deacetylase(gene name synonym)|uniprotkb:YPO2682(locus name)|uniprotkb:YP_2484(locus name)|uniprotkb:y1255(locus name)	psi-mi:zmiz1_human(display_long)|uniprotkb:ZMIZ1(gene name)|psi-mi:ZMIZ1(display_short)|uniprotkb:KIAA1224(gene name synonym)|uniprotkb:ZIMP10(gene name synonym)|uniprotkb:RAI17(gene name synonym)|uniprotkb:Retinoic acid-induced protein 17(gene name synonym)|uniprotkb:PIAS-like protein Zimp10(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849449|imex:IM-13779-5356	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR006879(YdjC-like protein)|interpro:IPR022948|go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0005737""(cytoplasm)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0019213""(deacetylase activity)|go:""GO:0036311""(chitin disaccharide deacetylase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0052777""(diacetylchitobiose catabolic process)|refseq:WP_002212244.1|refseq:YP_002347630.1|panther:PTHR31609(orthology-group)"	"ensembl:ENSG00000108175.19(gene)|ensembl:ENST00000334512.10(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007296""(vitellogenesis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016925""(protein sumoylation)|go:""GO:0021852""(pyramidal neuron migration to cerebral cortex)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0045747""(positive regulation of Notch signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046332""(SMAD binding)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048589""(developmental growth)|go:""GO:0048844""(artery morphogenesis)|go:""GO:0060395""(SMAD protein signal transduction)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:0090398""(cellular senescence)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040797|mint:Q9ULJ6|rcsb pdb:5AIZ|refseq:NP_065071.1|refseq:XP_011538282.1|refseq:XP_016871931.1|efo:""Orphanet:528084""|panther:PTHR10782(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pYqUZfBmwRlqczCS0iM02q3LMNo632	rogid:gqMqBRe+muLdsN5jD0SGo6r88a09606	intact-crc:B199BE483B2E54FC|rigid:WZQ8NqENr6KakPRGSpG1ylIoEcA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H4I2	uniprotkb:Q8CKL9	intact:EBI-948582|uniprotkb:O43145|uniprotkb:E1P5W5|uniprotkb:F5H820|uniprotkb:Q6NUJ7|ensembl:ENSP00000312222.4|ensembl:ENSP00000415498.3|ensembl:ENSP00000452965.1|ensembl:ENSP00000454006.1|ensembl:ENSP00000506788.1	intact:EBI-2849463|uniprotkb:Q74Q90	psi-mi:zhx3_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 3(gene name synonym)|uniprotkb:Triple homeobox protein 1(gene name synonym)|uniprotkb:ZHX3(gene name)|psi-mi:ZHX3(display_short)|uniprotkb:KIAA0395(gene name synonym)|uniprotkb:TIX1(gene name synonym)	psi-mi:q8ckl9_yerpe(display_long)|uniprotkb:y3289(locus name)|uniprotkb:YP_3600(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849467|imex:IM-13779-5357	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055850.1|refseq:XP_005260398.1|refseq:XP_011527022.1|refseq:XP_016883226.1|refseq:XP_016883227.1|ensembl:ENSG00000174306.22(gene)|ensembl:ENST00000309060.7(transcript)|ensembl:ENST00000432768.6(transcript)|ensembl:ENST00000559234.5(transcript)|ensembl:ENST00000560361.5(transcript)|ensembl:ENST00000683867.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0030154""(cell differentiation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR024578|interpro:IPR036236|interpro:IPR041057|mint:Q9H4I2|rcsb pdb:2DA5|rcsb pdb:2DN0|panther:PTHR15467(orthology-group)"	"go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KjDKgUE5s2Kt0y+E2UgmK0Pu2b89606	rogid:reO+RwzsQmogxtNDIEQ2oey9+Bo632	intact-crc:BB1F9F3118A6CB65|rigid:BLTxf53pTLA0MHgrsZ9JU0rBito	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6X8	uniprotkb:A0A5P8YB62	intact:EBI-948566|ensembl:ENSP00000314709.4	intact:EBI-2844412|uniprotkb:Q74RA2|uniprotkb:Q0WAD3|uniprotkb:Q7CKZ7|uniprotkb:A0A0H2W7C0|uniprotkb:A0A384KQ85	psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym)	psi-mi:a0a5p8yb62_yerpe(display_long)|uniprotkb:YPO3879(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849481|imex:IM-13779-5360	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055758.1|refseq:XP_005250893.1|refseq:XP_005250894.1|refseq:XP_011515233.1|refseq:XP_011515234.1|ensembl:ENSG00000178764.8(gene)|ensembl:ENST00000314393.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0060040""(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q9Y6X8|rcsb pdb:2DMP|rcsb pdb:3NAU|panther:PTHR15467(orthology-group)"	"interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR018030|interpro:IPR025885|interpro:IPR025949|interpro:IPR043142|refseq:WP_002211999.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR042186|interpro:IPR037224|refseq:YP_002348755.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606	rogid:LoLtCTl+KcIEJlQnZYPeOB8LOg4632	intact-crc:91A3012D7C9817C1|rigid:s2zF6LM4xZNoWxSSRvnMOnypO3M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5H9K5	uniprotkb:Q8D0V0	intact:EBI-2818620|uniprotkb:Q8NDS3|uniprotkb:Q96JN6|ensembl:ENSP00000361868.3|ensembl:ENSP00000437529.1|uniprotkb:A0A494C0A7	intact:EBI-2849272	psi-mi:zmat1_human(display_long)|uniprotkb:ZMAT1(gene name)|psi-mi:ZMAT1(display_short)|uniprotkb:KIAA1789(gene name synonym)	psi-mi:q8d0v0_yerpe(display_long)|uniprotkb:fadL(gene name)|psi-mi:fadL(display_short)|uniprotkb:Outer membrane FadL protein(gene name synonym)|uniprotkb:Outer membrane flp protein(gene name synonym)|uniprotkb:y1577(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849456|imex:IM-13779-5359	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269329.1|refseq:NP_001269330.1|ensembl:ENSG00000166432.16(gene)|ensembl:ENST00000372782.4(transcript)|ensembl:ENST00000540921.5(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0008270""(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q5H9K5|refseq:XP_006724774.1|refseq:XP_016885393.1|refseq:NP_001011657.2|refseq:XP_005262271.2|panther:PTHR46742(orthology-group)"	"interpro:IPR005017(Membrane protein involved in aromatic hydrocarbon degradation)|go:""GO:0006869""(lipid transport)|go:""GO:0009279""(cell outer membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:x57BXk4z+gt/z0FKa8Ro2EazCho9606	rogid:t3ttYDBykbAjdOq/JpJE2QGeyvk632	intact-crc:56FFDE033FFABE39|rigid:JZfchc+XUkXDpNUY/YQMwk6hZAg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6X8	uniprotkb:Q8CZX8	intact:EBI-948566|ensembl:ENSP00000314709.4	intact:EBI-2842787|uniprotkb:Q74S00	psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym)	psi-mi:q8czx8_yerpe(display_long)|uniprotkb:lysR(gene name)|psi-mi:lysR(display_short)|uniprotkb:lysR17(gene name synonym)|uniprotkb:YP_2860(locus name)|uniprotkb:y3185(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849474|imex:IM-13779-5358	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055758.1|refseq:XP_005250893.1|refseq:XP_005250894.1|refseq:XP_011515233.1|refseq:XP_011515234.1|ensembl:ENSG00000178764.8(gene)|ensembl:ENST00000314393.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0060040""(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q9Y6X8|rcsb pdb:2DMP|rcsb pdb:3NAU|panther:PTHR15467(orthology-group)"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606	rogid:EsQj+JSnKznEgjvjnq0+lLlaUlg632	intact-crc:222B3DBD0AE3E44D|rigid:elMgAQQmAPlk8z/ytlCva1nCnT0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6X8	uniprotkb:A0A2U2H077	intact:EBI-948566|ensembl:ENSP00000314709.4	intact:EBI-2841812|uniprotkb:Q74VJ9|uniprotkb:A0A384LD89|uniprotkb:Q0WHC7|uniprotkb:Q7CHD8|uniprotkb:A0A380PPP8	psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym)	psi-mi:a0a2u2h077_yerpe(display_long)|uniprotkb:mtr(gene name)|psi-mi:mtr(display_short)|uniprotkb:YPO1285(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849495|imex:IM-13779-5361	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055758.1|refseq:XP_005250893.1|refseq:XP_005250894.1|refseq:XP_011515233.1|refseq:XP_011515234.1|ensembl:ENSG00000178764.8(gene)|ensembl:ENST00000314393.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0060040""(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q9Y6X8|rcsb pdb:2DMP|rcsb pdb:3NAU|panther:PTHR15467(orthology-group)"	"interpro:IPR018227|interpro:IPR013059(Tryptophan/tyrosine transporter)|interpro:IPR006311(Twin-arginine translocation pathway signal)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005886""(plasma membrane)|go:""GO:0015173""(aromatic amino acid transmembrane transporter activity)|refseq:YP_002346311.1|refseq:WP_002208812.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606	rogid:M4JTYX328BR2JznjfkTVzEKmmW4632	intact-crc:9B159DE152885ABE|rigid:ZqlblgbBoT9GUHORClFvXMFU7RQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6X8	uniprotkb:Q8ZH69	intact:EBI-948566|ensembl:ENSP00000314709.4	intact:EBI-2841373|uniprotkb:Q74S45|uniprotkb:Q0WI04|uniprotkb:Q8CZY9	psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym)	psi-mi:dapd_yerpe(display_long)|uniprotkb:dapD(gene name)|psi-mi:dapD(display_short)|uniprotkb:Tetrahydrodipicolinate N-succinyltransferase(gene name synonym)|uniprotkb:YPO1041(locus name)|uniprotkb:y3140(locus name)|uniprotkb:YP_2810(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849516|imex:IM-13779-5363	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055758.1|refseq:XP_005250893.1|refseq:XP_005250894.1|refseq:XP_011515233.1|refseq:XP_011515234.1|ensembl:ENSG00000178764.8(gene)|ensembl:ENST00000314393.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0060040""(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q9Y6X8|rcsb pdb:2DMP|rcsb pdb:3NAU|panther:PTHR15467(orthology-group)"	"interpro:IPR005664(2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR018357|interpro:IPR023180|interpro:IPR011004(Trimeric LpxA-like)|rcsb pdb:3GOS|go:""GO:0005737""(cytoplasm)|go:""GO:0008666""(2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity)|go:""GO:0009085""(lysine biosynthetic process)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0019877""(diaminopimelate biosynthetic process)|refseq:WP_002212128.1|refseq:YP_002346084.1|interpro:IPR037133|panther:PTHR19136(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606	rogid:RB/vonogxMhlp8Guka34drbrmNo632	intact-crc:F0F32E540AAB0C63|rigid:lfJBaOMT/Ids/RBijfkNNFfq6xg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6X8	uniprotkb:A0A2S9PIH8	intact:EBI-948566|ensembl:ENSP00000314709.4	intact:EBI-2845089|uniprotkb:Q74RZ9|uniprotkb:Q0WIN7|uniprotkb:Q7CGZ1|uniprotkb:A0A384KV76	psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym)	psi-mi:a0a2s9pih8_yerpe(display_long)|uniprotkb:lysA(gene name)|psi-mi:lysA(display_short)|uniprotkb:YPO0796(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849502|imex:IM-13779-5365	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055758.1|refseq:XP_005250893.1|refseq:XP_005250894.1|refseq:XP_011515233.1|refseq:XP_011515234.1|ensembl:ENSG00000178764.8(gene)|ensembl:ENST00000314393.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0060040""(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q9Y6X8|rcsb pdb:2DMP|rcsb pdb:3NAU|panther:PTHR15467(orthology-group)"	"interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR002986(Diaminopimelate decarboxylase)|interpro:IPR022643|interpro:IPR022644|interpro:IPR000183(Orn/DAP/Arg decarboxylase 2)|interpro:IPR022653|interpro:IPR022657|interpro:IPR029066|go:""GO:0008836""(diaminopimelate decarboxylase activity)|go:""GO:0009089""(lysine biosynthetic process via diaminopimelate)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:WP_002209846.1|refseq:YP_002345851.1|panther:PTHR43727(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606	rogid:PVmk2FT176nUnOdaH1n3olLPC7Q632	intact-crc:64FD9A6AF0F23A43|rigid:qpL1TPi64t7AuNatVQU+zmb+w8Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y6X8	uniprotkb:A0A0H2W1Q2	intact:EBI-948566|ensembl:ENSP00000314709.4	intact:EBI-2841226|uniprotkb:Q0WBC6|uniprotkb:Q74X91|uniprotkb:Q7CKK4|uniprotkb:A0A380PGZ4	psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym)	psi-mi:a0a0h2w1q2_yerpe(display_long)|uniprotkb:YPO3523(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849488|imex:IM-13779-5364	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055758.1|refseq:XP_005250893.1|refseq:XP_005250894.1|refseq:XP_011515233.1|refseq:XP_011515234.1|ensembl:ENSG00000178764.8(gene)|ensembl:ENST00000314393.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0060040""(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q9Y6X8|rcsb pdb:2DMP|rcsb pdb:3NAU|panther:PTHR15467(orthology-group)"	"refseq:YP_002348412.1|interpro:IPR007452(Protein of unknown function DUF490)|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|refseq:WP_002210167.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606	rogid:EAskKEVuhdiV6Cq5qm8N8/ACmOw632	intact-crc:9450FAC75617A0AA|rigid:8/4yXyrfqZbx18PuCGtLldV3258	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKY1	uniprotkb:Q8CL89	intact:EBI-347767|uniprotkb:Q8IWD8|ensembl:ENSP00000297857.2|ensembl:ENSP00000378938.2|ensembl:ENSP00000428821.1|intact:EBI-28969235	intact:EBI-2839866	psi-mi:zhx1_human(display_long)|uniprotkb:ZHX1(gene name)|psi-mi:ZHX1(display_short)	psi-mi:q8cl89_yerpe(display_long)|uniprotkb:y1833(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849523|imex:IM-13779-5366	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165156.15(gene)|ensembl:ENST00000297857.3(transcript)|ensembl:ENST00000395571.8(transcript)|ensembl:ENST00000522655.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0030154""(cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR024578|interpro:IPR036236|interpro:IPR041057|mint:Q9UKY1|rcsb pdb:2ECB|rcsb pdb:2GHF|rcsb pdb:2LY9|rcsb pdb:3NAR|refseq:NP_001017926.1|refseq:NP_009153.3|panther:PTHR15467(orthology-group)"	interpro:IPR051551	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WAYc3kUjWyhNmhghUHlhYlLFxdc9606	rogid:kFqNelFqfI7J+vafdsofmQ0p0zA632	intact-crc:94AD0F694CF71908|rigid:4ZtJhVm8ts4eYniijTpYeYUt4B8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAB3	uniprotkb:Q9Y6X8	intact:EBI-2843827|uniprotkb:Q0WAB5	intact:EBI-948566|ensembl:ENSP00000314709.4	psi-mi:ilvd_yerpe(display_long)|uniprotkb:ilvD(gene name)|psi-mi:ilvD(display_short)|uniprotkb:YPO3897(locus name)|uniprotkb:y0338(locus name)|uniprotkb:YP_3150(locus name)	psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849509|imex:IM-13779-5362	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004404(Dihydroxy-acid dehydratase)|interpro:IPR000581(Dihydroxy-acid and 6-phosphogluconate dehydratase)|interpro:IPR020558|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004160""(dihydroxy-acid dehydratase activity)|go:""GO:0005829""(cytosol)|go:""GO:0009097""(isoleucine biosynthetic process)|go:""GO:0009099""(L-valine biosynthetic process)|go:""GO:0016836""(hydro-lyase activity)|go:""GO:0051537""(2 iron, 2 sulfur cluster binding)|refseq:WP_002212014.1|interpro:IPR037237|interpro:IPR042096|refseq:YP_002348773.1|panther:PTHR43661(orthology-group)"	"refseq:NP_055758.1|refseq:XP_005250893.1|refseq:XP_005250894.1|refseq:XP_011515233.1|refseq:XP_011515234.1|ensembl:ENSG00000178764.8(gene)|ensembl:ENST00000314393.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0035019""(somatic stem cell population maintenance)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045665""(negative regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0060040""(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q9Y6X8|rcsb pdb:2DMP|rcsb pdb:3NAU|panther:PTHR15467(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WzBeSkTt0zJwVJ9+DopV7Z9iYeM632	rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606	intact-crc:9251D75408E68835|rigid:2cFRkbgpsS9u1N8df/yt0g7XP1I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKY1	uniprotkb:Q8CKI5	intact:EBI-347767|uniprotkb:Q8IWD8|ensembl:ENSP00000297857.2|ensembl:ENSP00000378938.2|ensembl:ENSP00000428821.1|intact:EBI-28969235	intact:EBI-2849533	psi-mi:zhx1_human(display_long)|uniprotkb:ZHX1(gene name)|psi-mi:ZHX1(display_short)	psi-mi:q8cki5_yerpe(display_long)|uniprotkb:y3438(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849530|imex:IM-13779-5371	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165156.15(gene)|ensembl:ENST00000297857.3(transcript)|ensembl:ENST00000395571.8(transcript)|ensembl:ENST00000522655.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0030154""(cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR024578|interpro:IPR036236|interpro:IPR041057|mint:Q9UKY1|rcsb pdb:2ECB|rcsb pdb:2GHF|rcsb pdb:2LY9|rcsb pdb:3NAR|refseq:NP_001017926.1|refseq:NP_009153.3|panther:PTHR15467(orthology-group)"	"interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR001547(Glycoside hydrolase, family 5)|go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WAYc3kUjWyhNmhghUHlhYlLFxdc9606	rogid:NaohIRUgCnyb8tw5yehX4X/jpHw632	intact-crc:9C9E58694F71B266|rigid:mfQDbS9BDeBleSWsrGbOH1/JSTs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKY1	uniprotkb:A0A380PDY1	intact:EBI-347767|uniprotkb:Q8IWD8|ensembl:ENSP00000297857.2|ensembl:ENSP00000378938.2|ensembl:ENSP00000428821.1|intact:EBI-28969235	intact:EBI-2848416|uniprotkb:Q74UI0|uniprotkb:A0A0H2W558|uniprotkb:Q7CIW0|uniprotkb:A0A384L8E0	psi-mi:zhx1_human(display_long)|uniprotkb:ZHX1(gene name)|psi-mi:ZHX1(display_short)	psi-mi:a0a380pdy1_yerpe(display_long)|uniprotkb:ogl(gene name)|psi-mi:ogl(display_short)|uniprotkb:YPO1713(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849540|imex:IM-13779-5367	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165156.15(gene)|ensembl:ENST00000297857.3(transcript)|ensembl:ENST00000395571.8(transcript)|ensembl:ENST00000522655.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0030154""(cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR024578|interpro:IPR036236|interpro:IPR041057|mint:Q9UKY1|rcsb pdb:2ECB|rcsb pdb:2GHF|rcsb pdb:2LY9|rcsb pdb:3NAR|refseq:NP_001017926.1|refseq:NP_009153.3|panther:PTHR15467(orthology-group)"	"interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027946|refseq:WP_002210841.1|go:""GO:0045490""(pectin catabolic process)|go:""GO:0047487""(oligogalacturonide lyase activity)|refseq:YP_002346716.1|panther:PTHR36842(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WAYc3kUjWyhNmhghUHlhYlLFxdc9606	rogid:e8mn+xTHxqbWMCnpEvzfGUD7MYI632	intact-crc:B6A8DF51F2ABE21A|rigid:hj9ss35p04n5OyaKqf9omlJGnhU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BQ24	uniprotkb:A0A2U2GZF4	intact:EBI-2849569|uniprotkb:A8K3A4|uniprotkb:Q86T05|uniprotkb:Q96LT1|ensembl:ENSP00000310543.2	intact:EBI-2849561|uniprotkb:Q74RD5|uniprotkb:A0A0H2W735|uniprotkb:Q7CL16|uniprotkb:A0A384KCV3	psi-mi:zfy21_human(display_long)|uniprotkb:ZFYVE21(gene name)|psi-mi:ZFYVE21(display_short)	psi-mi:a0a2u2gzf4_yerpe(display_long)|uniprotkb:YPO3923(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849566|imex:IM-13779-5369	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001185882.1|refseq:NP_076976.1|ensembl:ENSG00000100711.14(gene)|ensembl:ENST00000311141.7(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005925""(focal adhesion)|go:""GO:0046872""(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR032031|interpro:IPR038632|interpro:IPR052113|rcsb pdb:2RRF|panther:PTHR39490(orthology-group)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR011276(TonB-dependent haem/haemoglobin receptor)|interpro:IPR010949(TonB-dependent haemoglobin/transferrin/lactoferrin receptor)|refseq:WP_002209485.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015232""(heme transmembrane transporter activity)|go:""GO:0015344""(siderophore uptake transmembrane transporter activity)|go:""GO:0044718""(siderophore transmembrane transport)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|refseq:YP_002348797.1|panther:PTHR30069(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IFI2oKWoBhLL4Wodwc1Rq442zrY9606	rogid:SBKji7kt36hZmFEe/debtzMNi2k632	intact-crc:AF0AB11C51CF25EA|rigid:eEwyyTOjMn3tSFfHvGFkVD4bb/g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UKY1	uniprotkb:A0A2U2GXJ4	intact:EBI-347767|uniprotkb:Q8IWD8|ensembl:ENSP00000297857.2|ensembl:ENSP00000378938.2|ensembl:ENSP00000428821.1|intact:EBI-28969235	intact:EBI-2840915|uniprotkb:Q74Y41|uniprotkb:A0A384KPW0|uniprotkb:Q7CFX2|uniprotkb:Q0WKG9|uniprotkb:A0A0H2W132	psi-mi:zhx1_human(display_long)|uniprotkb:ZHX1(gene name)|psi-mi:ZHX1(display_short)	psi-mi:a0a2u2gxj4_yerpe(display_long)|uniprotkb:feoA(gene name)|psi-mi:feoA(display_short)|uniprotkb:YPO0133(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849547|imex:IM-13779-5370	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165156.15(gene)|ensembl:ENST00000297857.3(transcript)|ensembl:ENST00000395571.8(transcript)|ensembl:ENST00000522655.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0030154""(cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR024578|interpro:IPR036236|interpro:IPR041057|mint:Q9UKY1|rcsb pdb:2ECB|rcsb pdb:2GHF|rcsb pdb:2LY9|rcsb pdb:3NAR|refseq:NP_001017926.1|refseq:NP_009153.3|panther:PTHR15467(orthology-group)"	"interpro:IPR007167(Ferrous iron transporter, FeoA subunit)|interpro:IPR008988(Transcriptional repressor, C-terminal)|refseq:YP_002345219.1|go:""GO:0046914""(transition metal ion binding)|interpro:IPR038157|refseq:WP_002208918.1|interpro:IPR052713"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:WAYc3kUjWyhNmhghUHlhYlLFxdc9606	rogid:Cncvuchy10judg2RDKVdBo+4A/s632	intact-crc:6F7689498106EF5A|rigid:mxOH/WqxJWQeRXAu7XaGoPGsWlA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAR2	uniprotkb:Q9UKY1	intact:EBI-2842016|uniprotkb:Q0WAS9	intact:EBI-347767|uniprotkb:Q8IWD8|ensembl:ENSP00000297857.2|ensembl:ENSP00000378938.2|ensembl:ENSP00000428821.1|intact:EBI-28969235	psi-mi:pur2_yerpe(display_long)|uniprotkb:purD(gene name)|psi-mi:purD(display_short)|uniprotkb:GARS(gene name synonym)|uniprotkb:Glycinamide ribonucleotide synthetase(gene name synonym)|uniprotkb:Phosphoribosylglycinamide synthetase(gene name synonym)|uniprotkb:YPO3729(locus name)|uniprotkb:y0501(locus name)|uniprotkb:YP_3092(locus name)	psi-mi:zhx1_human(display_long)|uniprotkb:ZHX1(gene name)|psi-mi:ZHX1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849554|imex:IM-13779-5368	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020561|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR020560|interpro:IPR020559|interpro:IPR020562|interpro:IPR011054(Rudiment single hybrid motif)|rcsb pdb:3MJF|go:""GO:0004637""(phosphoribosylamine-glycine ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0009113""(purine nucleobase biosynthetic process)|go:""GO:0046872""(metal ion binding)|refseq:WP_002210691.1|interpro:IPR037123|refseq:YP_002348609.1|panther:PTHR43472(orthology-group)"	"ensembl:ENSG00000165156.15(gene)|ensembl:ENST00000297857.3(transcript)|ensembl:ENST00000395571.8(transcript)|ensembl:ENST00000522655.5(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0030154""(cell differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|go:""GO:0046982""(protein heterodimerization activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR024578|interpro:IPR036236|interpro:IPR041057|mint:Q9UKY1|rcsb pdb:2ECB|rcsb pdb:2GHF|rcsb pdb:2LY9|rcsb pdb:3NAR|refseq:NP_001017926.1|refseq:NP_009153.3|panther:PTHR15467(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lCNHTp0WZiZKDpeBBaNkuNmlzIc632	rogid:WAYc3kUjWyhNmhghUHlhYlLFxdc9606	intact-crc:009FD3804EE0815C|rigid:zpL81/omzmJTfjK4P0WXmsK8nwg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZFW5	uniprotkb:Q96KR1	intact:EBI-2849587|uniprotkb:Q8D082|uniprotkb:Q0WGL4	intact:EBI-2513582|uniprotkb:Q9Y687|uniprotkb:Q6P5A3|uniprotkb:B2RNR5|uniprotkb:Q9H6V4|uniprotkb:Q3B7X5|uniprotkb:Q05C08|uniprotkb:Q9NTI1|uniprotkb:Q86UA0|intact:EBI-2560216|ensembl:ENSP00000265069.8	psi-mi:y1560_yerpe(display_long)|uniprotkb:YPO1560(locus name)|uniprotkb:y2607(locus name)|uniprotkb:YP_1448(locus name)	psi-mi:zfr_human(display_long)|uniprotkb:ZFR(gene name)|psi-mi:ZFR(display_short)|uniprotkb:M-phase phosphoprotein homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849592|imex:IM-13779-5374	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR007458(Protein of unknown function DUF496)|refseq:WP_002217522.1|go:""GO:0005829""(cytosol)|refseq:YP_002346574.1|interpro:IPR053375|panther:PTHR39591(orthology-group)"	"ensembl:ENSG00000056097.16(gene)|ensembl:ENST00000265069.13(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR006561(DZF)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043519|interpro:IPR049401|interpro:IPR049402|mint:Q96KR1|refseq:NP_057191.2|dip:DIP-47293N|efo:""Orphanet:401840""|panther:PTHR45762(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/Wk07OAP0vaV9flVx0m9Z4E+4o8632	rogid:UQQP+tkUcQYka9ez6rMv2F6FXFM9606	intact-crc:1D11BD6BFE7ED6A2|rigid:HGv6yPsIDlX1VTROHS/Zc49Cc+0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z3T8	uniprotkb:A0A2S9PFE9	intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|uniprotkb:Q5H9U2|ensembl:ENSP00000337159.5|ensembl:ENSP00000423663.1|ensembl:ENSP00000426848.1	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym)	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849580|imex:IM-13779-5372	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000039319.17(gene)|ensembl:ENST00000338008.9(transcript)|ensembl:ENST00000505560.5(transcript)|ensembl:ENST00000510158.5(transcript)|go:""GO:0005545""(1-phosphatidylinositol binding)|go:""GO:0005547""(phosphatidylinositol-3,4,5-trisphosphate binding)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0007165""(signal transduction)|go:""GO:0016050""(vesicle organization)|go:""GO:0016197""(endosomal transport)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0031901""(early endosome membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|mint:Q7Z3T8|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_005248689.1|refseq:XP_011542055.1|refseq:XP_016865580.1|refseq:XP_016865581.1|panther:PTHR46319(orthology-group)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	intact-crc:EE99E3BFD81887DE|rigid:emhyrQ+Mugnhb2Q94OZBuFdooZk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15911	uniprotkb:Q56950	intact:EBI-2849611|uniprotkb:Q13719|uniprotkb:O15101|uniprotkb:Q6ZP98|uniprotkb:D3DWS8|ensembl:ENSP00000268489.5|ensembl:ENSP00000493252.1|intact:EBI-28968693	intact:EBI-2849623|uniprotkb:Q7CI39|uniprotkb:A0A2S9PH07|uniprotkb:A0A1U8QEL9|uniprotkb:A0A3N4B1G1	psi-mi:zfhx3_human(display_long)|uniprotkb:AT motif-binding factor 1(gene name synonym)|uniprotkb:ZFHX3(gene name)|psi-mi:ZFHX3(display_short)|uniprotkb:ATBF1(gene name synonym)|uniprotkb:AT-binding transcription factor 1(gene name synonym)|uniprotkb:Alpha-fetoprotein enhancer-binding protein(gene name synonym)|uniprotkb:Zinc finger homeodomain protein 3(gene name synonym)|uniprotkb:C16orf47(gene name synonym)	psi-mi:q56950_yerpe(display_long)|uniprotkb:irp5(gene name)|psi-mi:irp5(display_short)|uniprotkb:ybtE(gene name synonym)|uniprotkb:YPO1907(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849620|imex:IM-13779-5373	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001158238.1|refseq:NP_008816.3|ensembl:ENSG00000140836.17(gene)|ensembl:ENST00000268489.10(transcript)|ensembl:ENST00000641206.2(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005667""(transcription regulator complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007517""(muscle organ development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016604""(nuclear body)|go:""GO:0019899""(enzyme binding)|go:""GO:0032922""(circadian regulation of gene expression)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045663""(positive regulation of myoblast differentiation)|go:""GO:0045664""(regulation of neuron differentiation)|go:""GO:0045785""(positive regulation of cell adhesion)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0071559""(response to transforming growth factor beta)|go:""GO:1904059""(regulation of locomotor rhythm)|interpro:IPR001356(Homeobox)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017970|interpro:IPR036236|interpro:IPR051968|mint:Q15911|rcsb pdb:2DA1|rcsb pdb:2DA2|rcsb pdb:2DA3|reactome:R-HSA-8941855|refseq:NP_997268.1|refseq:XP_016878717.1|refseq:XP_016878718.1|panther:PTHR45891(orthology-group)"	"interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR025110|refseq:WP_001088826.1|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0016020""(membrane)|go:""GO:0016877""(ligase activity, forming carbon-sulfur bonds)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002346898.1|interpro:IPR050237|interpro:IPR045851|panther:PTHR43859(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PCTLSDb8//3KuRhpHykw3cIIJOg9606	rogid:NbRnysmgHYiKsL79wxVDhJgOHbo632	intact-crc:3EF8FC6A0F94C0E9|rigid:TtrOqnf5pvWDKxACswED+FoV2oQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96KR1	uniprotkb:Q8D1M2	intact:EBI-2513582|uniprotkb:Q9Y687|uniprotkb:Q6P5A3|uniprotkb:B2RNR5|uniprotkb:Q9H6V4|uniprotkb:Q3B7X5|uniprotkb:Q05C08|uniprotkb:Q9NTI1|uniprotkb:Q86UA0|intact:EBI-2560216|ensembl:ENSP00000265069.8	intact:EBI-2849599|uniprotkb:Q74Y66	psi-mi:zfr_human(display_long)|uniprotkb:ZFR(gene name)|psi-mi:ZFR(display_short)|uniprotkb:M-phase phosphoprotein homolog(gene name synonym)	psi-mi:q8d1m2_yerpe(display_long)|uniprotkb:acrA1(gene name)|psi-mi:acrA1(display_short)|uniprotkb:YP_0101(locus name)|uniprotkb:y0287(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849604|imex:IM-13779-5375	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000056097.16(gene)|ensembl:ENST00000265069.13(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0003727""(single-stranded RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR006561(DZF)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043519|interpro:IPR049401|interpro:IPR049402|mint:Q96KR1|refseq:NP_057191.2|dip:DIP-47293N|efo:""Orphanet:401840""|panther:PTHR45762(orthology-group)"	"interpro:IPR006144(Secretion protein HlyD, conserved site)|interpro:IPR011053(Single hybrid motif)|go:""GO:0009306""(protein secretion)|go:""GO:0016020""(membrane)|interpro:IPR050739"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UQQP+tkUcQYka9ez6rMv2F6FXFM9606	rogid:81koSqzmbeM9XH9qVt8tsKLcazY632	intact-crc:A59B49D5FFEFA85E|rigid:HDFkGzCcQHWRF1bf39yZSOZld/Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJL7	uniprotkb:P31629	intact:EBI-2842639|uniprotkb:Q7CLC4|uniprotkb:Q0WKL7|uniprotkb:Q74Y85	intact:EBI-2514157|uniprotkb:Q02646|uniprotkb:Q9NS05|uniprotkb:Q5THT5|ensembl:ENSP00000012134.2|ensembl:ENSP00000356575.2|ensembl:ENSP00000356576.1|ensembl:ENSP00000515552.1	psi-mi:fief_yerpe(display_long)|uniprotkb:fieF(gene name)|psi-mi:fieF(display_short)|uniprotkb:YPO0077(locus name)|uniprotkb:y0060(locus name)|uniprotkb:YP_0079(locus name)	psi-mi:zep2_human(display_long)|uniprotkb:HIVEP2(gene name)|psi-mi:HIVEP2(display_short)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 2(gene name synonym)|uniprotkb:MHC-binding protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849646|imex:IM-13779-5377	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002524(Cation efflux protein)|interpro:IPR023783|interpro:IPR027470|go:""GO:0005886""(plasma membrane)|go:""GO:0006882""(intracellular zinc ion homeostasis)|go:""GO:0015086""(cadmium ion transmembrane transporter activity)|go:""GO:0015093""(ferrous iron transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015341""(zinc efflux antiporter activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002208967.1|interpro:IPR027469|interpro:IPR036837|refseq:YP_002345171.1|interpro:IPR050291|panther:PTHR43840(orthology-group)"	"ensembl:ENSG00000010818.11(gene)|ensembl:ENST00000012134.7(transcript)|ensembl:ENST00000367603.8(transcript)|ensembl:ENST00000367604.6(transcript)|ensembl:ENST00000703918.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR051969|refseq:NP_006725.3|refseq:XP_016866294.1|efo:""Orphanet:178469""|panther:PTHR45944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VwUTCeAraTPobF5+sDeJWDT3VEY632	rogid:/QXXmthWJq/FkgWwIqkVb1z16EU9606	intact-crc:0EC81B85C040DFCD|rigid:IxlgkQbIw2mUKgXVuVqn22xHv0E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15822	uniprotkb:Q8D0G2	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	intact:EBI-2849671|uniprotkb:Q74U08	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	psi-mi:q8d0g2_yerpe(display_long)|uniprotkb:lysR10(gene name)|psi-mi:lysR10(display_short)|uniprotkb:YP_1951(locus name)|uniprotkb:y2171(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849676|imex:IM-13779-5378	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|go:""GO:0003700""(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	rogid:kgk8m6ijxWIaMY451J073owPUn4632	intact-crc:7120623755376AF0|rigid:zftbMTutkvJOsdaB8eo5nTShA2w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31629	uniprotkb:Q0WJT0	intact:EBI-2514157|uniprotkb:Q02646|uniprotkb:Q9NS05|uniprotkb:Q5THT5|ensembl:ENSP00000012134.2|ensembl:ENSP00000356575.2|ensembl:ENSP00000356576.1|ensembl:ENSP00000515552.1	intact:EBI-2848005|uniprotkb:A0A3N4BBH4|uniprotkb:Q74XB0|uniprotkb:A0A0H2W350|uniprotkb:Q7CKL8|uniprotkb:A0A384LB40	psi-mi:zep2_human(display_long)|uniprotkb:HIVEP2(gene name)|psi-mi:HIVEP2(display_short)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 2(gene name synonym)|uniprotkb:MHC-binding protein 2(gene name synonym)	psi-mi:q0wjt0_yerpe(display_long)|uniprotkb:rnr(gene name)|psi-mi:rnr(display_short)|uniprotkb:vacB(gene name synonym)|uniprotkb:YPO0380(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849632|imex:IM-13779-5376	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000010818.11(gene)|ensembl:ENST00000012134.7(transcript)|ensembl:ENST00000367603.8(transcript)|ensembl:ENST00000367604.6(transcript)|ensembl:ENST00000703918.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR051969|refseq:NP_006725.3|refseq:XP_016866294.1|efo:""Orphanet:178469""|panther:PTHR45944(orthology-group)"	"interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013223(Ribonuclease B, OB region N-terminal)|interpro:IPR004476(RNase II and RNase R, bacteria)|interpro:IPR011805(Ribonuclease R, bacterial)|interpro:IPR013668(Ribonuclease R winged-helix domain)|interpro:IPR040476|refseq:WP_002209159.1|go:""GO:0003723""(RNA binding)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0008859""(exoribonuclease II activity)|go:""GO:0016070""(RNA metabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR011991(Winged helix repressor DNA-binding)|refseq:YP_002345458.1|interpro:IPR050180"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/QXXmthWJq/FkgWwIqkVb1z16EU9606	rogid:jBGTi4O5QHZXkNIanuHOpATLT7Q632	intact-crc:BFA3DE5349D10BAC|rigid:/mdCKBdT2QKhVtd93hfMMsKNLF8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H4H5	uniprotkb:P31629	intact:EBI-2840718|uniprotkb:Q74QU3|uniprotkb:A0A384KBL5|uniprotkb:A0A0H2W7L1|uniprotkb:Q7CG19	intact:EBI-2514157|uniprotkb:Q02646|uniprotkb:Q9NS05|uniprotkb:Q5THT5|ensembl:ENSP00000012134.2|ensembl:ENSP00000356575.2|ensembl:ENSP00000356576.1|ensembl:ENSP00000515552.1	psi-mi:a0a2u2h4h5_yerpe(display_long)|uniprotkb:dppB(gene name)|psi-mi:dppB(display_short)|uniprotkb:ISU56_01415(orf name)|uniprotkb:ISU59_01410(orf name)|uniprotkb:YPO4002(locus name)	psi-mi:zep2_human(display_long)|uniprotkb:HIVEP2(gene name)|psi-mi:HIVEP2(display_short)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 2(gene name synonym)|uniprotkb:MHC-binding protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849639|imex:IM-13779-5379	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:YP_002348870.1|go:""GO:0005886""(plasma membrane)|go:""GO:0071916""(dipeptide transmembrane transporter activity)|interpro:IPR035906|interpro:IPR045621|panther:PTHR43163(orthology-group)"	"ensembl:ENSG00000010818.11(gene)|ensembl:ENST00000012134.7(transcript)|ensembl:ENST00000367603.8(transcript)|ensembl:ENST00000367604.6(transcript)|ensembl:ENST00000703918.1(transcript)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR051969|refseq:NP_006725.3|refseq:XP_016866294.1|efo:""Orphanet:178469""|panther:PTHR45944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t6DtAXJvQYdpOXJQ03y6RzwNH6w632	rogid:/QXXmthWJq/FkgWwIqkVb1z16EU9606	intact-crc:9F2F2A81EA28A30F|rigid:9ClgsKU1ftoOD3cQcmOqOeGueEU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15822	uniprotkb:A0A6B3VBG2	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	intact:EBI-2849663	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	psi-mi:a0a6b3vbg2_yerpe(display_long)|uniprotkb:yapB(gene name)|psi-mi:yapB(display_short)|uniprotkb:y1345(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849660|imex:IM-13779-5381	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	"interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|uniprotkb:A0A6B3T6Y5(uniprot-removed-ac)|go:""GO:0019867""(outer membrane)|interpro:IPR051551"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	rogid:jNPx4rqCv9bEZelj7jbp42kW+NY632	intact-crc:896D4E794B26C782|rigid:+SBSvdJHizGgWM5VxGW/MEtzEyM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15822	uniprotkb:Q8ZGR6	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	intact:EBI-2844456|uniprotkb:Q0WHI9	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	psi-mi:ubig_yerpe(display_long)|uniprotkb:ubiG(gene name)|psi-mi:ubiG(display_short)|uniprotkb:2-polyprenyl-6-hydroxyphenol methylase(gene name synonym)|uniprotkb:3-demethylubiquinone 3-O-methyltransferase(gene name synonym)|uniprotkb:YPO1215(locus name)|uniprotkb:YP_0922(locus name)|uniprotkb:y2973(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849653|imex:IM-13779-5380	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	"interpro:IPR029063|interpro:IPR010233(Ubiquinone biosynthesis O-methyltransferase)|go:""GO:0008168""(methyltransferase activity)|go:""GO:0010420""(polyprenyldihydroxybenzoate methyltransferase activity)|go:""GO:0032259""(methylation)|go:""GO:0061542""(3-demethylubiquinol 3-O-methyltransferase activity)|go:""GO:0102208""(2-polyprenyl-6-hydroxyphenol methylase activity)|refseq:WP_002210820.1|refseq:YP_002346249.1|panther:PTHR43464(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	rogid:HQ8DZ/0XF59YGNXPYkTGaS2XvHQ632	intact-crc:E375968954406480|rigid:Fxji+QlmtG+G/3I9r1FgsJp/vNo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15822	uniprotkb:A0A5P8YBQ9	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	intact:EBI-2844830|uniprotkb:Q74X93|uniprotkb:A0A0H2W369|uniprotkb:Q7CKK6|uniprotkb:A0A2U2GXX7|uniprotkb:A0A384KXD1	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	psi-mi:a0a5p8ybq9_yerpe(display_long)|uniprotkb:YPO3526(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849701|imex:IM-13779-5383	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	"interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR005170(Transporter-associated region)|interpro:IPR044751|go:""GO:0005886""(plasma membrane)|go:""GO:0050660""(flavin adenine dinucleotide binding)|refseq:WP_002210164.1|interpro:IPR036318|refseq:YP_002348415.1|interpro:IPR046342"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	rogid:JC3IVKKYgEftNqAeJWJ+daHPtRo632	intact-crc:67A1190B829A77E8|rigid:mRkc0U2dQjCSbb0FUhWW5DUTKjE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A7Y8RCW6	uniprotkb:P15822	intact:EBI-2845056|uniprotkb:Q7CKM5|uniprotkb:A0A5P8YBL8|uniprotkb:Q0WJU7	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	psi-mi:a0a7y8rcw6_yerpe(display_long)|uniprotkb:YPO0363(locus name)	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849694|imex:IM-13779-5385	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR024393|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR011066(Mechanosensitive ion channel MscS, C-terminal)|interpro:IPR006685(Mechanosensitive ion channel MscS)|interpro:IPR011014(Mechanosensitive ion channel MscS, transmembrane-2)|interpro:IPR006686(Mechanosensitive ion channel MscS, conserved site)|interpro:IPR025692|go:""GO:0005886""(plasma membrane)|go:""GO:0008381""(mechanosensitive monoatomic ion channel activity)|interpro:IPR049142|interpro:IPR049278|interpro:IPR023408|refseq:YP_002345441.1|interpro:IPR052702"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:z6l0v0GxSQqbhV/esC/hffWqLG8632	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	intact-crc:7B881B6E6E7AC4A0|rigid:S5VRtbiXIb4vwWaylizjdeCxNx0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15822	uniprotkb:Q8ZGX4	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	intact:EBI-2840069|uniprotkb:Q74W78|uniprotkb:Q0WHQ0|uniprotkb:Q7CH64	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	psi-mi:6pgl_yerpe(display_long)|uniprotkb:pgl(gene name)|psi-mi:pgl(display_short)|uniprotkb:YPO1149(locus name)|uniprotkb:y3033(locus name)|uniprotkb:YP_1011(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849720|imex:IM-13779-5386	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	"refseq:YP_002346188.1|interpro:IPR022528|interpro:IPR019405|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0009051""(pentose-phosphate shunt, oxidative branch)|go:""GO:0017057""(6-phosphogluconolactonase activity)|refseq:WP_002210760.1|interpro:IPR050282|panther:PTHR30344(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	rogid:noKVC/wB8Hf1xbPbMQHTszCjTss632	intact-crc:401F968954FBC477|rigid:H6WAgSnm0rl0CdxKxaXIeY+fHpY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P15822	uniprotkb:A0A0H2W2G1	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	intact:EBI-2849711|uniprotkb:Q74Y32|uniprotkb:Q0WKF6|uniprotkb:A0A384KHE2|uniprotkb:Q7CFW5	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	psi-mi:a0a0h2w2g1_yerpe(display_long)|uniprotkb:YPO0146(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849708|imex:IM-13779-5384	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	interpro:IPR005883(Type IV pilus assembly protein PilM)|interpro:IPR043129|refseq:YP_002345232.1|interpro:IPR050696	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	rogid:2sWQKvWEVSiUFEJ8OURtsksFAQo632	intact-crc:2AD8F49C6F7F6F21|rigid:0GV7j5z16JCK+nV/Zo7cUvSZgas	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D097	uniprotkb:P15822	intact:EBI-2849686	intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698.2|ensembl:ENSP00000417348.2|ensembl:ENSP00000418021.2|ensembl:ENSP00000419762.2	psi-mi:q8d097_yerpe(display_long)|uniprotkb:ptrB(gene name)|psi-mi:ptrB(display_short)|uniprotkb:y2527(locus name)	psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849683|imex:IM-13779-5382	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023302|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002470(Peptidase S9A, prolyl oligopeptidase)|interpro:IPR029058|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:WP_002231190.1|interpro:IPR051543"	"refseq:NP_002105.3|ensembl:ENSG00000095951.18(gene)|ensembl:ENST00000379388.7(transcript)|ensembl:ENST00000478545.2(transcript)|ensembl:ENST00000487103.6(transcript)|ensembl:ENST00000491710.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016604""(nuclear body)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|interpro:IPR051969|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|refseq:XP_011512853.1|refseq:XP_011512854.1|refseq:XP_011512855.1|panther:PTHR45944(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:e1PUtAFibeLqTuVlv0AfdoPCzZQ632	rogid:v5WUuKMFkL3q+rIW5Q9aEh0zOBU9606	intact-crc:9BDE62375409B5BD|rigid:LJmww6FHMPc7QWB8Zo2q9poeQcw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P37275	uniprotkb:P68590	intact:EBI-2849734|uniprotkb:Q12924|uniprotkb:Q5T968|uniprotkb:Q13800|uniprotkb:Q2KJ05|uniprotkb:B4DJV0|uniprotkb:B4DUW9|uniprotkb:E9PCM7|uniprotkb:F5H4I8|uniprotkb:Q5VZ84|uniprotkb:Q8NB68|intact:EBI-11153310|ensembl:ENSP00000319248.9	intact:EBI-2845098|uniprotkb:Q00929	psi-mi:zeb1_human(display_long)|uniprotkb:ZEB1(gene name)|psi-mi:ZEB1(display_short)|uniprotkb:AREB6(gene name synonym)|uniprotkb:TCF8(gene name synonym)|uniprotkb:NIL-2-A zinc finger protein(gene name synonym)|uniprotkb:Negative regulator of IL2(gene name synonym)|uniprotkb:Transcription factor 8(gene name synonym)	psi-mi:yopr_yerpe(display_long)|uniprotkb:yscH(gene name)|psi-mi:yscH(display_short)|uniprotkb:lcrP(gene name synonym)|uniprotkb:Yersinia outer protein R(gene name synonym)|uniprotkb:Yersinia secretion protein H(gene name synonym)|uniprotkb:yopR(gene name synonym)|uniprotkb:YPCD1.57(locus name)|uniprotkb:YP_pCD26(locus name)|uniprotkb:y0024(locus name)|uniprotkb:y5021(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849742|imex:IM-13779-5387	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000148516.23(gene)|ensembl:ENST00000320985.14(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0003682""(chromatin binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007389""(pattern specification process)|go:""GO:0007417""(central nervous system development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010464""(regulation of mesenchymal cell proliferation)|go:""GO:0010839""(negative regulation of keratinocyte proliferation)|go:""GO:0014823""(response to activity)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030154""(cell differentiation)|go:""GO:0030900""(forebrain development)|go:""GO:0031667""(response to nutrient levels)|go:""GO:0033081""(regulation of T cell differentiation in thymus)|go:""GO:0043616""(keratinocyte proliferation)|go:""GO:0045602""(negative regulation of endothelial cell differentiation)|go:""GO:0045666""(positive regulation of neuron differentiation)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048596""(embryonic camera-type eye morphogenesis)|go:""GO:0048704""(embryonic skeletal system morphogenesis)|go:""GO:0048752""(semicircular canal morphogenesis)|go:""GO:0051150""(regulation of smooth muscle cell differentiation)|go:""GO:0051216""(cartilage development)|go:""GO:0070888""(E-box binding)|go:""GO:0071230""(cellular response to amino acid stimulus)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0090103""(cochlea morphogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR008598(Drought induced 19)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR051574|mint:P37275|rcsb pdb:2E19|reactome:R-HSA-6785807|refseq:NP_001121600.1|refseq:NP_001167564.1|refseq:NP_001167565.1|refseq:NP_001167566.1|refseq:NP_001167567.1|refseq:NP_110378.3|efo:""Orphanet:98973""|efo:""Orphanet:98974""|panther:PTHR24391(orthology-group)"	"interpro:IPR013349(Type III secretion system effector YopR)|refseq:NP_395191.1|refseq:NP_857725.1|refseq:NP_857920.1|go:""GO:0005576""(extracellular region)|go:""GO:0030254""(protein secretion by the type III secretion system)|go:""GO:0030257""(type III protein secretion system complex)|rcsb pdb:1Z21|refseq:WP_002212915.1|mint:P68590|interpro:IPR041814"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2QwbT74tbgA6Jec85fGMRYg0EBI9606	rogid:vLBOGgil8yDmtkZgVzl8ti6IGok632	intact-crc:2E27EE5F617DD1F7|rigid:wLdERcHaTd/Xj/0l1ApIqyNJViY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NYG2	uniprotkb:A0A380PC31	intact:EBI-740248|uniprotkb:Q53A17|uniprotkb:Q96BL0|ensembl:ENSP00000395502.2	intact:EBI-2847467|uniprotkb:Q74TQ8|uniprotkb:Q7CII9|uniprotkb:Q0WEL8	psi-mi:zdhc3_human(display_long)|uniprotkb:Zinc finger DHHC domain-containing protein 3(gene name synonym)|uniprotkb:Protein DHHC1(gene name synonym)|uniprotkb:ZDHHC3(gene name)|psi-mi:ZDHHC3(display_short)|uniprotkb:HSD49(orf name)|uniprotkb:Acyltransferase ZDHHC3(gene name synonym)	psi-mi:a0a380pc31_yerpe(display_long)|uniprotkb:pntA(gene name)|psi-mi:pntA(display_short)|uniprotkb:YPO2303(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849761|imex:IM-13779-5390	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001128651.1|refseq:NP_057682.1|ensembl:ENSG00000163812.16(gene)|ensembl:ENST00000424952.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0008277""(regulation of G protein-coupled receptor signaling pathway)|go:""GO:0016020""(membrane)|go:""GO:0016409""(palmitoyltransferase activity)|go:""GO:0018230""(peptidyl-L-cysteine S-palmitoylation)|go:""GO:0018345""(protein palmitoylation)|go:""GO:0019705""(protein-cysteine S-myristoyltransferase activity)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0032230""(positive regulation of synaptic transmission, GABAergic)|go:""GO:0034165""(positive regulation of toll-like receptor 9 signaling pathway)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0044873""(lipoprotein localization to membrane)|go:""GO:0072657""(protein localization to membrane)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0140439""(protein-cysteine S-stearoyltransferase activity)|go:""GO:1902685""(positive regulation of receptor localization to synapse)|go:""GO:1903546""(protein localization to photoreceptor outer segment)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR039859|mint:Q9NYG2|reactome:R-HSA-9694548|refseq:XP_016862055.1|refseq:XP_016862056.1|panther:PTHR22883(orthology-group)"	"interpro:IPR026255|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR024605|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|refseq:WP_002211019.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006740""(NADPH regeneration)|go:""GO:0008750""(""proton-translocating NAD(P)+ transhydrogenase activity"")|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0050661""(NADP binding)|interpro:IPR036291|refseq:YP_002347270.1|panther:PTHR10160(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tumJntnDjlE0U3k6gHZwsQO+BLI9606	rogid:FVP+mtiTI6lGXb+9R8nUXq43tEc632	intact-crc:F2A6A06CF3B35E66|rigid:ZdLbk2zGxXHOrbPqmRq2jax1RbI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0Q9	uniprotkb:O60315	intact:EBI-2839753	intact:EBI-717614|uniprotkb:A0JP09|uniprotkb:Q9UED1|uniprotkb:B7Z2P2|uniprotkb:F5H814|ensembl:ENSP00000386854.2|ensembl:ENSP00000454157.1|ensembl:ENSP00000487174.1	psi-mi:q8d0q9_yerpe(display_long)|uniprotkb:rne(gene name)|psi-mi:rne(display_short)|uniprotkb:y1749(locus name)	psi-mi:zeb2_human(display_long)|uniprotkb:Zinc finger homeobox protein 1b(gene name synonym)|uniprotkb:Smad-interacting protein 1(gene name synonym)|uniprotkb:ZEB2(gene name)|psi-mi:ZEB2(display_short)|uniprotkb:KIAA0569(gene name synonym)|uniprotkb:SIP1(gene name synonym)|uniprotkb:ZFX1B(gene name synonym)|uniprotkb:HRIHFB2411(orf name)|uniprotkb:ZFHX1B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849727|imex:IM-13779-5389	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR028878|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR021968|interpro:IPR003029(S1, RNA binding)|interpro:IPR019307|interpro:IPR004659(Ribonuclease E and G)|interpro:IPR048583|go:""GO:0000049""(tRNA binding)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006364""(rRNA processing)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0008033""(tRNA processing)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008995""(ribonuclease E activity)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0019843""(rRNA binding)|refseq:WP_002224293.1"	"efo:""Orphanet:261537""|efo:""Orphanet:261552""|ensembl:ENSG00000169554.23(gene)|ensembl:ENST00000409487.7(transcript)|ensembl:ENST00000558170.6(transcript)|ensembl:ENST00000627532.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007399""(nervous system development)|go:""GO:0007417""(central nervous system development)|go:""GO:0010764""(negative regulation of fibroblast migration)|go:""GO:0019208""(phosphatase regulator activity)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0036446""(myofibroblast differentiation)|go:""GO:0043149""(stress fiber assembly)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0045636""(positive regulation of melanocyte differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0048023""(positive regulation of melanin biosynthetic process)|go:""GO:0048066""(developmental pigmentation)|go:""GO:0048143""(astrocyte activation)|go:""GO:0070269""(pyroptotic inflammatory response)|go:""GO:0072537""(fibroblast activation)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090649""(response to oxygen-glucose deprivation)|go:""GO:0097324""(melanocyte migration)|go:""GO:1903056""(regulation of melanosome organization)|go:""GO:1904330""(positive regulation of myofibroblast contraction)|go:""GO:1904520""(regulation of myofibroblast cell apoptotic process)|go:""GO:1905603""(regulation of blood-brain barrier permeability)|interpro:IPR001356(Homeobox)|interpro:IPR008598(Drought induced 19)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR051574|mint:O60315|rcsb pdb:2DA7|reactome:R-HSA-9762293|reactome:R-HSA-9823739|reactome:R-HSA-9832991|refseq:NP_001165124.1|refseq:NP_055610.1|refseq:XP_006712944.1|refseq:XP_006712945.1|efo:""Orphanet:626""|panther:PTHR24391(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:byCDxnHD7BmEbq3ebGvOu4sr/U8632	rogid:KIKq943mmyO6wbsDamXsyo0OnEo9606	intact-crc:64957271A1A59572|rigid:zOoUm7UZO/HT3ct7XNRxEhX0y48	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1D2	uniprotkb:Q9C0B5	intact:EBI-2849752|uniprotkb:Q74X70	intact:EBI-2799626|uniprotkb:Q8TAK8|uniprotkb:Q9H923|uniprotkb:Q9UFI7|uniprotkb:Q6ZMF0|uniprotkb:Q2TGF0|ensembl:ENSP00000287169.3	psi-mi:q8d1d2_yerpe(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:y0687(locus name)	psi-mi:zdhc5_human(display_long)|uniprotkb:KIAA1748(gene name synonym)|uniprotkb:ZNF375(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 5(gene name synonym)|uniprotkb:Zinc finger protein 375(gene name synonym)|uniprotkb:ZDHHC5(gene name)|psi-mi:ZDHHC5(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849749|imex:IM-13779-5388	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010214(Transcription termination factor NusA, C-terminal duplication)|interpro:IPR010213(Transcription termination factor NusA)|interpro:IPR025249|interpro:IPR030842|go:""GO:0000166""(nucleotide binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0031564""(transcription antitermination)|interpro:IPR036555"	"refseq:XP_011543201.1|refseq:XP_011543202.1|refseq:XP_011543203.1|refseq:NP_056272.2|ensembl:ENSG00000156599.11(gene)|ensembl:ENST00000287169.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0016020""(membrane)|go:""GO:0016409""(palmitoyltransferase activity)|go:""GO:0018345""(protein palmitoylation)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0030425""(dendrite)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0062208""(positive regulation of pattern recognition receptor signaling pathway)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0098982""(GABA-ergic synapse)|go:""GO:0099072""(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:""GO:0099091""(postsynaptic specialization, intracellular component)|go:""GO:0140639""(positive regulation of pyroptotic inflammatory response)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1903078""(positive regulation of protein localization to plasma membrane)|go:""GO:1905171""(positive regulation of protein localization to phagocytic vesicle)|interpro:IPR001594(Zinc finger, DHHC-type)|mint:Q9C0B5|reactome:R-HSA-9694548|panther:PTHR12349(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:YzZfDXwWbJbXKFeHL1SADDhW96Q632	rogid:4EKCQeKXifPU/7fv6uPuHE7b1rU9606	intact-crc:4ADB8C4CCAB7AC05|rigid:iUe0A0s0AGwVfEHEZI85Tj2Cijo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z570	uniprotkb:A0A5P8YGC5	intact:EBI-948232|uniprotkb:Q6ZN26|uniprotkb:A7E253|intact:EBI-28975131|ensembl:ENSP00000303252.6	intact:EBI-2849807|uniprotkb:Q74VU0|uniprotkb:Q0WH08|uniprotkb:A0A2U2GUY6|uniprotkb:Q7CHK1|uniprotkb:A0A384LBD8	psi-mi:z804a_human(display_long)|uniprotkb:ZNF804A(gene name)|psi-mi:ZNF804A(display_short)|uniprotkb:C2orf10(gene name synonym)	psi-mi:a0a5p8ygc5_yerpe(display_long)|uniprotkb:YPO1407(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849811|imex:IM-13779-5393	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_919226.1|ensembl:ENSG00000170396.9(gene)|ensembl:ENST00000302277.7(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010975""(regulation of neuron projection development)|go:""GO:0010976""(positive regulation of neuron projection development)|go:""GO:0030426""(growth cone)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043197""(dendritic spine)|go:""GO:0043198""(dendritic shaft)|go:""GO:0046872""(metal ion binding)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:1901588""(dendritic microtubule)|go:""GO:1902952""(positive regulation of dendritic spine maintenance)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR052445|panther:PTHR17614(orthology-group)"	"interpro:IPR005490(ErfK/YbiS/YcfS/YnhG)|interpro:IPR002477(Peptidoglycan binding-like)|refseq:WP_002217987.1|go:""GO:0004180""(carboxypeptidase activity)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016740""(transferase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR038063|interpro:IPR036365|refseq:YP_002346430.1|interpro:IPR052905|interpro:IPR036366|interpro:IPR045380"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:XY3izL5Fvbcxm9i7Sp/bpXD/TUU9606	rogid:+H76sYlvscVAOr5fESmEns/NtHE632	intact-crc:A8C89F3D539789EC|rigid:OzxPMmCPusXx3g2Yj1QHyYo0/kk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P43403	uniprotkb:A0A0H2W3Z5	intact:EBI-1211276|uniprotkb:A6NFP4|uniprotkb:Q6PIA4|uniprotkb:Q8IXD6|uniprotkb:Q9UBS6|ensembl:ENSP00000264972.5|ensembl:ENSP00000513759.1|ensembl:ENSP00000517108.1|ensembl:ENSP00000517109.1	intact:EBI-2847103|uniprotkb:Q74WB5|uniprotkb:Q0WHM4|uniprotkb:Q7CH74|uniprotkb:A0A5P8YDY9|uniprotkb:A0A384KR65	psi-mi:zap70_human(display_long)|uniprotkb:ZAP70(gene name)|psi-mi:ZAP70(display_short)|uniprotkb:SRK(gene name synonym)|uniprotkb:Syk-related tyrosine kinase(gene name synonym)|uniprotkb:70 kDa zeta-chain associated protein(gene name synonym)	psi-mi:a0a0h2w3z5_yerpe(display_long)|uniprotkb:pbpG(gene name)|psi-mi:pbpG(display_short)|uniprotkb:YPO1176(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849800|imex:IM-13779-5392	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000115085.16(gene)|ensembl:ENSG00000291603.1(gene)|ensembl:ENST00000264972.10(transcript)|ensembl:ENST00000698508.2(transcript)|ensembl:ENST00000708152.1(transcript)|ensembl:ENST00000708154.1(transcript)|go:""GO:0001772""(immunological synapse)|go:""GO:0001784""(phosphotyrosine residue binding)|go:""GO:0002250""(adaptive immune response)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004715""(non-membrane spanning protein tyrosine kinase activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006955""(immune response)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0018108""(peptidyl-tyrosine phosphorylation)|go:""GO:0019722""(calcium-mediated signaling)|go:""GO:0030154""(cell differentiation)|go:""GO:0030217""(T cell differentiation)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042101""(T cell receptor complex)|go:""GO:0042110""(T cell activation)|go:""GO:0042113""(B cell activation)|go:""GO:0043366""(beta selection)|go:""GO:0045059""(positive thymic T cell selection)|go:""GO:0045060""(negative thymic T cell selection)|go:""GO:0045087""(innate immune response)|go:""GO:0045582""(positive regulation of T cell differentiation)|go:""GO:0046638""(positive regulation of alpha-beta T cell differentiation)|go:""GO:0046641""(positive regulation of alpha-beta T cell proliferation)|go:""GO:0050850""(positive regulation of calcium-mediated signaling)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0070489""(T cell aggregation)|go:""GO:0072678""(T cell migration)|go:""GO:0140801""(histone H2AXY142 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|interpro:IPR050198|mint:P43403|rcsb pdb:1FBV|rcsb pdb:1M61|rcsb pdb:1U59|rcsb pdb:2CBL|rcsb pdb:2OQ1|rcsb pdb:2OZO|rcsb pdb:2Y1N|rcsb pdb:3ZNI|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4K2R|rcsb pdb:4XZ0|rcsb pdb:4XZ1|rcsb pdb:5O76|rcsb pdb:7SIY|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-9013407|reactome:R-HSA-9725371|refseq:NP_001070.2|refseq:NP_997402.1|dip:DIP-38781N|efo:""Orphanet:911""|panther:PTHR24418(orthology-group)"	"interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR018044|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:WP_002210780.1|go:""GO:0006508""(proteolysis)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009002""(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0071555""(cell wall organization)|refseq:YP_002346214.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:21kVb/nxY2BBZPBNVwWba+qUOgc9606	rogid:C/KJqq0U7v8ImiY47xC4HPuOdyU632	intact-crc:924BEB2AC2EF1B04|rigid:0By5KgT3K46OvY3J0l7Nv5crAFk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O96006	uniprotkb:Q8CKF8	intact:EBI-740037|uniprotkb:Q96BY4|intact:EBI-25627346|ensembl:ENSP00000370616.3|ensembl:ENSP00000370620.2|ensembl:ENSP00000370621.4|ensembl:ENSP00000498725.1|ensembl:ENSP00000518653.1|ensembl:ENSP00000518654.1|ensembl:ENSP00000518655.1|ensembl:ENSP00000518656.1	intact:EBI-2844579|uniprotkb:Q74RR5	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:q8ckf8_yerpe(display_long)|uniprotkb:y3542(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849793|imex:IM-13779-5394	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717.12(gene)|ensembl:ENSG00000292345.1(gene)|ensembl:ENST00000381218.8(transcript)|ensembl:ENST00000381222.8(transcript)|ensembl:ENST00000381223.9(transcript)|ensembl:ENST00000652001.1(transcript)|ensembl:ENST00000711169.1(transcript)|ensembl:ENST00000711171.1(transcript)|ensembl:ENST00000711172.1(transcript)|ensembl:ENST00000711173.1(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0016605""(PML body)|go:""GO:0016925""(protein sumoylation)|go:""GO:0019789""(SUMO transferase activity)|go:""GO:0031965""(nuclear membrane)|go:""GO:0042802""(identical protein binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|go:""GO:0046983""(protein dimerization activity)|go:""GO:0061665""(SUMO ligase activity)|go:""GO:1990466""(protein autosumoylation)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|interpro:IPR052717|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|panther:PTHR46169(orthology-group)"	interpro:IPR037883	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:bULfeL7EI8ZLrm+OLqILFkvARMg632	intact-crc:1D82A4AF9A1D2946|rigid:iwOQDfyMRwYiQcsooCSx5lzOvE8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CGI0	uniprotkb:Q96K62	intact:EBI-2840021|uniprotkb:Q74RN4	intact:EBI-714373|ensembl:ENSP00000346603.2|ensembl:ENSP00000469089.1|ensembl:ENSP00000473072.1	psi-mi:ftsp_yerpe(display_long)|uniprotkb:ftsP(gene name)|psi-mi:ftsP(display_short)|uniprotkb:YPO0673(locus name)|uniprotkb:YP_2989(locus name)|uniprotkb:y3504(locus name)	psi-mi:zbt45_human(display_long)|uniprotkb:Zinc finger protein 499(gene name synonym)|uniprotkb:ZBTB45(gene name)|psi-mi:ZBTB45(display_short)|uniprotkb:ZNF499(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849786|imex:IM-13779-5391	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002345741.1|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR008972(Cupredoxin)|interpro:IPR006311(Twin-arginine translocation pathway signal)|interpro:IPR026589|refseq:WP_002212176.1|go:""GO:0005507""(copper ion binding)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|interpro:IPR045087|panther:PTHR11709(orthology-group)"	"refseq:XP_006723508.1|refseq:NP_116181.1|ensembl:ENSG00000119574.13(gene)|ensembl:ENST00000354590.7(transcript)|ensembl:ENST00000594051.6(transcript)|ensembl:ENST00000600990.1(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0001227""(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002682""(regulation of immune system process)|go:""GO:0005654""(nucleoplasm)|go:""GO:0007399""(nervous system development)|go:""GO:0046872""(metal ion binding)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050457|refseq:NP_001303907.1|refseq:NP_001303908.1|refseq:NP_001303909.1|refseq:NP_001303910.1|refseq:NP_001303911.1|dip:DIP-62048N|panther:PTHR24399(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JQTwQ8R/Yza07pQepCvAhD8UkWA632	rogid:d/0uRGCcjIstHKC0lueXr62+Pic9606	intact-crc:8D2DA022C4042330|rigid:/4Ei1YMAc9gBPMKPN9rHmO00n7U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IVQ6	uniprotkb:A0A2S9PKW4	intact:EBI-2849773|uniprotkb:Q5VWG1|uniprotkb:A8KA95|uniprotkb:D3DRI7|ensembl:ENSP00000370303.3	intact:EBI-2849768|uniprotkb:Q74WE2|uniprotkb:A0A5P8YE16|uniprotkb:Q7CH90|uniprotkb:A0A0H2W1N2	psi-mi:zdh21_human(display_long)|uniprotkb:ZDHHC21(gene name)|psi-mi:ZDHHC21(display_short)|uniprotkb:Zinc finger DHHC domain-containing protein 21(gene name synonym)|uniprotkb:DHHC domain-containing cysteine-rich protein 21(gene name synonym)	psi-mi:a0a2s9pkw4_yerpe(display_long)|uniprotkb:dinG(gene name)|psi-mi:dinG(display_short)|uniprotkb:DNA 5'-3' helicase DinG(gene name synonym)|uniprotkb:rarB(gene name synonym)|uniprotkb:YPO1206(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849779|imex:IM-13779-5395	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_848661.1|refseq:XP_016870171.1|refseq:XP_016870172.1|refseq:XP_016870173.1|refseq:XP_016870174.1|refseq:XP_016870175.1|refseq:XP_016870176.1|refseq:XP_016870177.1|refseq:XP_016870178.1|refseq:XP_016870179.1|ensembl:ENSG00000175893.13(gene)|ensembl:ENST00000380916.9(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001942""(hair follicle development)|go:""GO:0003056""(regulation of vascular associated smooth muscle contraction)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0016409""(palmitoyltransferase activity)|go:""GO:0018230""(peptidyl-L-cysteine S-palmitoylation)|go:""GO:0018345""(protein palmitoylation)|go:""GO:0019706""(protein-cysteine S-palmitoyltransferase activity)|go:""GO:0046209""(nitric oxide metabolic process)|go:""GO:0048733""(sebaceous gland development)|go:""GO:0071875""(adrenergic receptor signaling pathway)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1904997""(regulation of leukocyte adhesion to arterial endothelial cell)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR039859|mint:Q8IVQ6|reactome:R-HSA-203615|reactome:R-HSA-9009391|panther:PTHR22883(orthology-group)"	"interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR010614(DEAD2)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR027417|refseq:WP_002210810.1|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|go:""GO:0016818""(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:""GO:0016853""(isomerase activity)|go:""GO:0043139""(5'-3' DNA helicase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR039000|refseq:YP_002346240.1|interpro:IPR045028"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SVzwhVR4AHW5msfTtjEiiR/OwBg9606	rogid:Pz/QYhpy8rsVBaUUTk559v1mAL4632	intact-crc:0F5FED91E82EA25F|rigid:vxSaCVl9CSne9OhwvsIm9PAAqJ4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O68743	uniprotkb:Q96TA2	intact:EBI-2849869|uniprotkb:A0A384L9N9|uniprotkb:Q74YP1|uniprotkb:Q7ARA6|uniprotkb:Q7BT23|uniprotkb:Q65AP4|uniprotkb:A0A1U8QGX5|uniprotkb:A0A5P8YM11|uniprotkb:A0A2U2H133	intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV9|uniprotkb:D3DRV8|uniprotkb:B4DNM1|ensembl:ENSP00000318480.3|intact:EBI-10989776	psi-mi:o68743_yerpe(display_long)|uniprotkb:YPMT1.25Ac(gene name)|psi-mi:YPMT1.25Ac(display_short)	psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849873|imex:IM-13779-5400	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_857662.1|refseq:NP_395362.1|refseq:YP_093903.1|refseq:WP_000176291.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|mint:O68743"	"ensembl:ENSG00000136758.21(gene)|ensembl:ENST00000326799.7(transcript)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0004176""(ATP-dependent peptidase activity)|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0006515""(protein quality control for misfolded or incompletely synthesized proteins)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010636""(positive regulation of mitochondrial fusion)|go:""GO:0016020""(membrane)|go:""GO:0016604""(nuclear body)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034214""(protein hexamerization)|go:""GO:0034982""(mitochondrial protein processing)|go:""GO:0035694""(mitochondrial protein catabolic process)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0097150""(neuronal stem cell population maintenance)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:2000035""(regulation of stem cell division)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664|reactome:R-HSA-9837999|reactome:R-HSA-9840373|refseq:NP_001240795.1|refseq:NP_055078.1|refseq:NP_647473.1|efo:""Orphanet:98676""|panther:PTHR23076(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/jUgpNFZ2rE3SwY62pqgY9qM8xs632	rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606	intact-crc:03DED9CBA648BBA0|rigid:HECgZQ2YFCGDn/v+nrAeyYbFl2g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZGX4	uniprotkb:Q6AHZ1	intact:EBI-2840069|uniprotkb:Q74W78|uniprotkb:Q0WHQ0|uniprotkb:Q7CH64	intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684.1|ensembl:ENSP00000481657.1|ensembl:ENSP00000485614.1	psi-mi:6pgl_yerpe(display_long)|uniprotkb:pgl(gene name)|psi-mi:pgl(display_short)|uniprotkb:YPO1149(locus name)|uniprotkb:y3033(locus name)|uniprotkb:YP_1011(locus name)	psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849830|imex:IM-13779-5399	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002346188.1|interpro:IPR022528|interpro:IPR019405|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|go:""GO:0005829""(cytosol)|go:""GO:0006006""(glucose metabolic process)|go:""GO:0009051""(pentose-phosphate shunt, oxidative branch)|go:""GO:0017057""(6-phosphogluconolactonase activity)|refseq:WP_002210760.1|interpro:IPR050282|panther:PTHR30344(orthology-group)"	"refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|ensembl:ENSG00000177853.15(gene)|ensembl:ENST00000316045.10(transcript)|ensembl:ENST00000614149.2(transcript)|ensembl:ENST00000624776.4(transcript)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006325""(chromatin organization)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050888|mint:Q6AHZ1|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|panther:PTHR24392(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:noKVC/wB8Hf1xbPbMQHTszCjTss632	rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606	intact-crc:1BD9A8BD19413828|rigid:0cS5AA3bMwvJxnwj+7xeK1Wp5Gg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6AHZ1	uniprotkb:Q8Z9S8	intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684.1|ensembl:ENSP00000481657.1|ensembl:ENSP00000485614.1	intact:EBI-2849818|uniprotkb:Q0W9R9	psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym)	psi-mi:glms_yerpe(display_long)|uniprotkb:glmS(gene name)|psi-mi:glmS(display_short)|uniprotkb:D-fructose-6-phosphate amidotransferase(gene name synonym)|uniprotkb:GFAT(gene name synonym)|uniprotkb:Glucosamine-6-phosphate synthase(gene name synonym)|uniprotkb:Hexosephosphate aminotransferase(gene name synonym)|uniprotkb:L-glutamine--D-fructose-6-phosphate amidotransferase(gene name synonym)|uniprotkb:YPO4118(locus name)|uniprotkb:YP_4025(locus name)|uniprotkb:y4132(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849823|imex:IM-13779-5396	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|ensembl:ENSG00000177853.15(gene)|ensembl:ENST00000316045.10(transcript)|ensembl:ENST00000614149.2(transcript)|ensembl:ENST00000624776.4(transcript)|go:""GO:0000977""(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006325""(chromatin organization)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0046872""(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR050888|mint:Q6AHZ1|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|panther:PTHR24392(orthology-group)"	"interpro:IPR017932|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR001347(""Sugar isomerase (SIS)"")|interpro:IPR029055|interpro:IPR035490|interpro:IPR035466|go:""GO:0004360""(""glutamine-fructose-6-phosphate transaminase (isomerizing) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006002""(fructose 6-phosphate metabolic process)|go:""GO:0006047""(UDP-N-acetylglucosamine metabolic process)|go:""GO:0006487""(protein N-linked glycosylation)|go:""GO:0097367""(carbohydrate derivative binding)|interpro:IPR047084|refseq:WP_002215552.1|refseq:YP_002348969.1|interpro:IPR046348|panther:PTHR10937(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606	rogid:gr9ulxOKd7cyp8e0SrmobX07CjI632	intact-crc:B56D56BD1AD72D21|rigid:/8W9H71Ad0aFzFEtvymGWTVElgg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z739	uniprotkb:P68587	intact:EBI-2849837|uniprotkb:Q659A3|uniprotkb:B3KXL4|uniprotkb:Q63Z37|ensembl:ENSP00000473496.2	intact:EBI-2844901|uniprotkb:P40295	psi-mi:ythd3_human(display_long)|uniprotkb:YTHDF3(gene name)|psi-mi:YTHDF3(display_short)	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849844|imex:IM-13779-5397	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_689971.4|refseq:NP_001264742.1|refseq:NP_001264743.1|refseq:NP_001264744.1|refseq:NP_001264745.1|refseq:NP_001264746.1|refseq:NP_001264747.1|ensembl:ENSG00000185728.17(gene)|ensembl:ENST00000539294.6(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0034063""(stress granule assembly)|go:""GO:0043022""(ribosome binding)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0045727""(positive regulation of translation)|go:""GO:0045948""(positive regulation of translational initiation)|go:""GO:0060339""(negative regulation of type I interferon-mediated signaling pathway)|go:""GO:0061157""(mRNA destabilization)|go:""GO:0070925""(organelle assembly)|go:""GO:1901163""(regulation of trophoblast cell migration)|go:""GO:1990247""(N6-methyladenosine-containing RNA reader activity)|interpro:IPR007275(YT521-B-like protein)|interpro:IPR045168|mint:Q7Z739|rcsb pdb:6ZOT|rcsb pdb:8BS5|rcsb pdb:8BS6|panther:PTHR12357(orthology-group)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M1/1RMOQiQ7kD+J9KMmEq9RZebw9606	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	intact-crc:57678ACEC0E965F2|rigid:mJJZgF2xSyCJNhYj/tuu/GGAmsc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O68749	uniprotkb:Q96MU7	intact:EBI-2849861|uniprotkb:A0A384KZF2|uniprotkb:Q74YN4|uniprotkb:Q7ARE2|uniprotkb:Q7BT24|uniprotkb:A0A0H2W0D2|uniprotkb:A0A1U8QPF6|uniprotkb:A0A3G5LCT8|uniprotkb:A0A2U2H122	intact:EBI-2849854|uniprotkb:Q4W5Q3|uniprotkb:Q7Z622|uniprotkb:Q8TF35|intact:EBI-28984617|ensembl:ENSP00000339245.4|ensembl:ENSP00000479213.1	psi-mi:o68749_yerpe(display_long)|uniprotkb:YPMT1.31(locus name)	psi-mi:ytdc1_human(display_long)|uniprotkb:YTHDC1(gene name)|psi-mi:YTHDC1(display_short)|uniprotkb:KIAA1966(gene name synonym)|uniprotkb:YT521(gene name synonym)|uniprotkb:Splicing factor YT521(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849851|imex:IM-13779-5398	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_857668.1|refseq:NP_395369.1|refseq:YP_093910.1|refseq:WP_002214131.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"refseq:NP_001026902.1|refseq:NP_588611.2|refseq:NP_001317627.1|ensembl:ENSG00000083896.13(gene)|ensembl:ENSG00000275272.4(gene)|ensembl:ENST00000344157.9(transcript)|ensembl:ENST00000615500.4(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006376""(mRNA splice site recognition)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0007283""(spermatogenesis)|go:""GO:0009048""(dosage compensation by inactivation of X chromosome)|go:""GO:0010608""(post-transcriptional regulation of gene expression)|go:""GO:0016607""(nuclear speck)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0048160""(primary follicle stage)|go:""GO:0110104""(mRNA alternative polyadenylation)|go:""GO:1990247""(N6-methyladenosine-containing RNA reader activity)|interpro:IPR007275(YT521-B-like protein)|interpro:IPR045168|mint:Q96MU7|rcsb pdb:2YUD|rcsb pdb:4R3H|rcsb pdb:4R3I|rcsb pdb:6RT4|rcsb pdb:6RT5|rcsb pdb:6RT6|rcsb pdb:6RT7|rcsb pdb:6SYZ|rcsb pdb:6SZ1|rcsb pdb:6SZ2|rcsb pdb:6SZ3|rcsb pdb:6SZL|rcsb pdb:6SZN|rcsb pdb:6SZR|rcsb pdb:6SZT|rcsb pdb:6SZX|rcsb pdb:6SZY|rcsb pdb:6T01|rcsb pdb:6T02|rcsb pdb:6T03|rcsb pdb:6T04|rcsb pdb:6T05|rcsb pdb:6T06|rcsb pdb:6T07|rcsb pdb:6T08|rcsb pdb:6T09|rcsb pdb:6T0A|rcsb pdb:6T0C|rcsb pdb:6T0D|rcsb pdb:6T0O|rcsb pdb:6T0X|rcsb pdb:6T0Z|rcsb pdb:6T10|rcsb pdb:6T11|rcsb pdb:6T12|rcsb pdb:6WE8|rcsb pdb:6WE9|rcsb pdb:6WEA|rcsb pdb:6YKE|rcsb pdb:6YKI|rcsb pdb:6YKJ|rcsb pdb:6YKZ|rcsb pdb:6YL0|rcsb pdb:6YL8|rcsb pdb:6YL9|rcsb pdb:6YM2|rcsb pdb:6YM8|rcsb pdb:6YNI|rcsb pdb:6YNJ|rcsb pdb:6YNK|rcsb pdb:6YNL|rcsb pdb:6YNM|rcsb pdb:6YNN|rcsb pdb:6YNO|rcsb pdb:6YNP|rcsb pdb:6YOQ|rcsb pdb:6ZCM|rcsb pdb:6ZCN|rcsb pdb:6ZD9|rcsb pdb:7L4X|rcsb pdb:7L4Y|rcsb pdb:7P87|rcsb pdb:7P88|rcsb pdb:7P8A|rcsb pdb:7P8B|rcsb pdb:7P8F|rcsb pdb:7PJ7|rcsb pdb:7PJ8|rcsb pdb:7PJ9|rcsb pdb:7PJA|rcsb pdb:7PJB|rcsb pdb:7PJP|rcsb pdb:7PJQ|rcsb pdb:7PO6|rcsb pdb:8K2E|rcsb pdb:8Q2Q|rcsb pdb:8Q2R|rcsb pdb:8Q2S|rcsb pdb:8Q2T|rcsb pdb:8Q2U|rcsb pdb:8Q2V|rcsb pdb:8Q2W|rcsb pdb:8Q2X|rcsb pdb:8Q2Y|rcsb pdb:8Q31|rcsb pdb:8Q32|rcsb pdb:8Q33|rcsb pdb:8Q35|rcsb pdb:8Q37|rcsb pdb:8Q38|rcsb pdb:8Q39|rcsb pdb:8Q3A|rcsb pdb:8Q3G|rcsb pdb:8Q4M|rcsb pdb:8Q4N|rcsb pdb:8Q4P|rcsb pdb:8Q4Q|rcsb pdb:8Q4R|rcsb pdb:8Q4T|rcsb pdb:8Q4U|rcsb pdb:8Q4V|rcsb pdb:8Q4W|panther:PTHR12357(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0IAXJ9lRnsjyXao1+mL7QBCXqqg632	rogid:vfZLRHOJvCdw6OIA9xeqeSgJZgE9606	intact-crc:DD5A4818489ED919|rigid:VMETrNMq7ioxi55ADpad2aFcLx4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P68587	uniprotkb:P67809	intact:EBI-2844901|uniprotkb:P40295	intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626.3	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849915|imex:IM-13779-5402	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"refseq:NP_004550.2|ensembl:ENSG00000065978.19(gene)|ensembl:ENST00000321358.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000932""(P-body)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005689""(U12-type spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0008544""(epidermis development)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0035198""(miRNA binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0048598""(embryonic morphogenesis)|go:""GO:0050658""(RNA transport)|go:""GO:0051020""(GTPase binding)|go:""GO:0051031""(tRNA transport)|go:""GO:0051154""(negative regulation of striated muscle cell differentiation)|go:""GO:0051781""(positive regulation of cell division)|go:""GO:0062153""(C5-methylcytidine-containing RNA reader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0070937""(CRD-mediated mRNA stability complex)|go:""GO:0071204""(histone pre-mRNA 3'end processing complex)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1990428""(miRNA transport)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|go:""GO:2000773""(negative regulation of cellular senescence)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|interpro:IPR050181|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-2173796|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-877300|reactome:R-HSA-9017802|dip:DIP-29405N|panther:PTHR11544(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606	intact-crc:9F27B50C49CFE95D|rigid:xR4jlxSWtXyhWngPLyifHknNvu4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BWQ6	uniprotkb:Q7ARD3	intact:EBI-751204|ensembl:ENSP00000253031.1|ensembl:ENSP00000466055.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:yipf2_human(display_long)|uniprotkb:YIP1 family member 2(gene name synonym)|uniprotkb:YIPF2(gene name)|psi-mi:YIPF2(display_short)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849908|imex:IM-13779-5404	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_076934.1|refseq:NP_001308368.1|refseq:XP_011526572.1|ensembl:ENSG00000130733.11(gene)|ensembl:ENST00000253031.6(transcript)|ensembl:ENST00000586748.6(transcript)|go:""GO:0000138""(Golgi trans cisterna)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030133""(transport vesicle)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|interpro:IPR006977(Yip1 domain)|interpro:IPR039765|mint:Q9BWQ6|panther:PTHR12822(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3XPsp3aO5nkDrU0yVBmfQGgYNG09606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:DA95D927B7F45E43|rigid:nQWb4cHM56QzTI1RyLkSq5dm8Ac	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CIA2	uniprotkb:Q9UM01	intact:EBI-2849892|uniprotkb:Q74U75	intact:EBI-2849880|uniprotkb:Q86U07|uniprotkb:Q9P2V5|uniprotkb:O95984|uniprotkb:Q53XC1|uniprotkb:B2RAU0|uniprotkb:D3DS26|ensembl:ENSP00000285850.7|ensembl:ENSP00000380662.4|ensembl:ENSP00000380663.2|ensembl:ENSP00000380666.4|ensembl:ENSP00000451881.1|ensembl:ENSP00000452551.2|ensembl:ENSP00000501493.1	"psi-mi:prmc_yerpe(display_long)|uniprotkb:N5-glutamine methyltransferase PrmC(gene name synonym)|uniprotkb:""Protein-(glutamine-N5) MTase PrmC""(gene name synonym)|uniprotkb:Protein-glutamine N-methyltransferase PrmC(gene name synonym)|uniprotkb:hemK(gene name synonym)|uniprotkb:YPO2018(locus name)|uniprotkb:YP_1866(locus name)|uniprotkb:y2289(locus name)|uniprotkb:prmC(gene name)|psi-mi:prmC(display_short)"	"psi-mi:ylat1_human(display_long)|uniprotkb:SLC7A7(gene name)|psi-mi:SLC7A7(display_short)|uniprotkb:Monocyte amino acid permease 2(gene name synonym)|uniprotkb:Solute carrier family 7 member 7(gene name synonym)|uniprotkb:""y(+)L-type amino acid transporter 1""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849889|imex:IM-13779-5405	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004556(Modification methylase HemK)|interpro:IPR019874|interpro:IPR025714|interpro:IPR029063|refseq:WP_002211235.1|interpro:IPR040758|go:""GO:0003676""(nucleic acid binding)|go:""GO:0006415""(translational termination)|go:""GO:0032259""(methylation)|go:""GO:0036009""(protein-glutamine N-methyltransferase activity)|go:""GO:0102559""(""peptide chain release factor N(5)-glutamine methyltransferase activity"")|refseq:YP_002347004.1|interpro:IPR050320|panther:PTHR18895(orthology-group)"	"ensembl:ENSG00000155465.21(gene)|ensembl:ENST00000285850.11(transcript)|ensembl:ENST00000397528.8(transcript)|ensembl:ENST00000397529.6(transcript)|ensembl:ENST00000397532.9(transcript)|ensembl:ENST00000555702.5(transcript)|ensembl:ENST00000555911.2(transcript)|ensembl:ENST00000674313.1(transcript)|go:""GO:0000821""(regulation of arginine metabolic process)|go:""GO:0003333""(amino acid transmembrane transport)|go:""GO:0005886""(plasma membrane)|go:""GO:0015174""(basic amino acid transmembrane transporter activity)|go:""GO:0015179""(L-amino acid transmembrane transporter activity)|go:""GO:0015820""(L-leucine transport)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0061459""(L-arginine transmembrane transporter activity)|go:""GO:1903826""(L-arginine transmembrane transport)|go:""GO:1990822""(basic amino acid transmembrane transport)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR050598|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|refseq:NP_001119577.1|refseq:NP_001119578.1|refseq:XP_006720365.1|refseq:XP_011535600.1|refseq:XP_011535601.1|efo:""Orphanet:470""|panther:PTHR11785(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:THdPGJ4n/c8dQ78xq18i7nKkalc632	rogid:aOP7rlnbxgZ080k/1BUpSXe25XU9606	intact-crc:0A73BD6C8851F3B1|rigid:h2ULo8GPVkvzhhq1DJW2eK7wTXU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P67809	uniprotkb:A0A2U2GWA7	intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626.3	intact:EBI-2849922|uniprotkb:Q74X25|uniprotkb:Q0WBK2|uniprotkb:A0A0H2W2T4|uniprotkb:Q7CKF7|uniprotkb:A0A384L802	psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym)	psi-mi:a0a2u2gwa7_yerpe(display_long)|uniprotkb:rraB(gene name)|psi-mi:rraB(display_short)|uniprotkb:YPO3445(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849926|imex:IM-13779-5403	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004550.2|ensembl:ENSG00000065978.19(gene)|ensembl:ENST00000321358.12(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000932""(P-body)|go:""GO:0001701""(in utero embryonic development)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005689""(U12-type spliceosomal complex)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0008544""(epidermis development)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0035198""(miRNA binding)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045202""(synapse)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0048598""(embryonic morphogenesis)|go:""GO:0050658""(RNA transport)|go:""GO:0051020""(GTPase binding)|go:""GO:0051031""(tRNA transport)|go:""GO:0051154""(negative regulation of striated muscle cell differentiation)|go:""GO:0051781""(positive regulation of cell division)|go:""GO:0062153""(C5-methylcytidine-containing RNA reader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070934""(CRD-mediated mRNA stabilization)|go:""GO:0070937""(CRD-mediated mRNA stability complex)|go:""GO:0071204""(histone pre-mRNA 3'end processing complex)|go:""GO:0098761""(cellular response to interleukin-7)|go:""GO:1900152""(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1990428""(miRNA transport)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000767""(positive regulation of cytoplasmic translation)|go:""GO:2000773""(negative regulation of cellular senescence)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|interpro:IPR050181|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-2173796|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-877300|reactome:R-HSA-9017802|dip:DIP-29405N|panther:PTHR11544(orthology-group)"	"interpro:IPR009671(Protein of unknown function DUF1260)|interpro:IPR016716(Uncharacterised conserved protein UCP018193)|refseq:WP_002209303.1|go:""GO:0005737""(cytoplasm)|go:""GO:0019899""(enzyme binding)|go:""GO:0060698""(endoribonuclease inhibitor activity)|interpro:IPR036701|refseq:YP_002348336.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606	rogid:cfBJHB3s59FKkcdAWBqEKWNHcTM632	intact-crc:6EA5E39B6BBAD2B0|rigid:SohQlIfIPnEFfybGHKjQTtJZYKA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BWQ6	uniprotkb:Q8D0R9	intact:EBI-751204|ensembl:ENSP00000253031.1|ensembl:ENSP00000466055.1	intact:EBI-2843556|uniprotkb:Q74T80	psi-mi:yipf2_human(display_long)|uniprotkb:YIP1 family member 2(gene name synonym)|uniprotkb:YIPF2(gene name)|psi-mi:YIPF2(display_short)	psi-mi:q8d0r9_yerpe(display_long)|uniprotkb:betT2(gene name)|psi-mi:betT2(display_short)|uniprotkb:YP_2309(locus name)|uniprotkb:y1693(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849901|imex:IM-13779-5401	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_076934.1|refseq:NP_001308368.1|refseq:XP_011526572.1|ensembl:ENSG00000130733.11(gene)|ensembl:ENST00000253031.6(transcript)|ensembl:ENST00000586748.6(transcript)|go:""GO:0000138""(Golgi trans cisterna)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005797""(Golgi medial cisterna)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0030133""(transport vesicle)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031902""(late endosome membrane)|interpro:IPR006977(Yip1 domain)|interpro:IPR039765|mint:Q9BWQ6|panther:PTHR12822(orthology-group)"	"interpro:IPR018093|interpro:IPR000060(BCCT transporter)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3XPsp3aO5nkDrU0yVBmfQGgYNG09606	rogid:VTp0zKwXM+uz4oOtpCdgNMt0IDs632	intact-crc:5346676B6AAE4909|rigid:Wyme4vUtFEzZr4BJVwfDBy7FW+k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IY57	uniprotkb:Q8ZDA6	intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256.2	intact:EBI-2843773|uniprotkb:Q0WDK8	psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short)	psi-mi:chbg_yerpe(display_long)|uniprotkb:chbG(gene name)|psi-mi:chbG(display_short)|uniprotkb:Chitin disaccharide deacetylase(gene name synonym)|uniprotkb:Chitobiose deacetylase(gene name synonym)|uniprotkb:Chitobiose-6P deacetylase(gene name synonym)|uniprotkb:Chitotriose deacetylase(gene name synonym)|uniprotkb:Chitotriose-6P deacetylase(gene name synonym)|uniprotkb:YPO2682(locus name)|uniprotkb:YP_2484(locus name)|uniprotkb:y1255(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849945|imex:IM-13779-5409	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153.15(gene)|ensembl:ENST00000534854.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|panther:PTHR12920(orthology-group)"	"interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR006879(YdjC-like protein)|interpro:IPR022948|go:""GO:0000272""(polysaccharide catabolic process)|go:""GO:0005737""(cytoplasm)|go:""GO:0006032""(chitin catabolic process)|go:""GO:0019213""(deacetylase activity)|go:""GO:0036311""(chitin disaccharide deacetylase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0052777""(diacetylchitobiose catabolic process)|refseq:WP_002212244.1|refseq:YP_002347630.1|panther:PTHR31609(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606	rogid:pYqUZfBmwRlqczCS0iM02q3LMNo632	intact-crc:2A934F82310E3E67|rigid:nNLu1AK7ctKQHM5uG4jSEm86/Cg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1P6	uniprotkb:Q8IZH2	intact:EBI-2839854	intact:EBI-372406|ensembl:ENSP00000264951.4|uniprotkb:Q4G0S3|uniprotkb:Q68D88|uniprotkb:Q6AI24|uniprotkb:Q6MZS8|uniprotkb:Q86WS7|uniprotkb:Q8N8U4|uniprotkb:Q9UF39	psi-mi:q8d1p6_yerpe(display_long)|uniprotkb:tcaC1(gene name)|psi-mi:tcaC1(display_short)|uniprotkb:y0185(locus name)	psi-mi:xrn1_human(display_long)|uniprotkb:Strand-exchange protein 1 homolog(gene name synonym)|uniprotkb:XRN1(gene name)|psi-mi:XRN1(display_short)|uniprotkb:SEP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849952|imex:IM-13779-5407	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003284(Salmonella virulence plasmid 65kDa B protein)|interpro:IPR022044|interpro:IPR022045|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|interpro:IPR028994"	"ensembl:ENSG00000114127.11(gene)|ensembl:ENST00000264951.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0002151""(G-quadruplex RNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004534""(5'-3' RNA exonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0016075""(rRNA catabolic process)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030425""(dendrite)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0033574""(response to testosterone)|go:""GO:0043025""(neuronal cell body)|go:""GO:0051880""(G-quadruplex DNA binding)|go:""GO:0070034""(telomerase RNA binding)|go:""GO:0071028""(nuclear mRNA surveillance)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:0071409""(cellular response to cycloheximide)|go:""GO:1905795""(cellular response to puromycin)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR016494(5'-3' exoribonuclease 1)|interpro:IPR027073|interpro:IPR040992|interpro:IPR041106|interpro:IPR041385|interpro:IPR041412|interpro:IPR047007|interpro:IPR047008|mint:Q8IZH2|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|refseq:NP_061874.3|refseq:NP_001269786.1|refseq:NP_001269788.1|dip:DIP-31174N|panther:PTHR12341(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:O/TCvNvvMc3GrD6oFI13BOD7NL8632	rogid:Y5wskamFEhJ+vmrGjlw4nYHiWLg9606	intact-crc:AB00B35337FCF225|rigid:PHI+MKcIRRFcggAq1sJmQcz1wfo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8IY57	uniprotkb:A0A5P8YIB0	intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256.2	intact:EBI-2849936|uniprotkb:Q74W18|uniprotkb:Q0WDQ9|uniprotkb:Q7CJU5|uniprotkb:A0A384K8S0	psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short)	psi-mi:a0a5p8yib0_yerpe(display_long)|uniprotkb:asnB(gene name)|psi-mi:asnB(display_short)|uniprotkb:YPO2623(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849933|imex:IM-13779-5406	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153.15(gene)|ensembl:ENST00000534854.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046872""(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|panther:PTHR12920(orthology-group)"	"interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR001962(Asparagine synthase)|interpro:IPR017932|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033738|interpro:IPR029055|refseq:WP_002210348.1|go:""GO:0004066""(""asparagine synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006529""(asparagine biosynthetic process)|refseq:YP_002347579.1|interpro:IPR050795|panther:PTHR11772(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606	rogid:/3AdfRR3qomx0JU+SwWtTPa2aeU632	intact-crc:07853522F6E07A3E|rigid:4JUufQroGPgH/7QULTvW+kKuGCk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YEP4	uniprotkb:Q8IZH2	intact:EBI-2842292|uniprotkb:Q74UV4|uniprotkb:Q7CHX9|uniprotkb:A0A2S9PKJ9|uniprotkb:Q0WFZ1	intact:EBI-372406|ensembl:ENSP00000264951.4|uniprotkb:Q4G0S3|uniprotkb:Q68D88|uniprotkb:Q6AI24|uniprotkb:Q6MZS8|uniprotkb:Q86WS7|uniprotkb:Q8N8U4|uniprotkb:Q9UF39	psi-mi:a0a5p8yep4_yerpe(display_long)|uniprotkb:Fla FV(gene name)|psi-mi:Fla FV(display_short)|uniprotkb:flaK(gene name synonym)|uniprotkb:flgE(gene name synonym)|uniprotkb:YPO1802(locus name)	psi-mi:xrn1_human(display_long)|uniprotkb:Strand-exchange protein 1 homolog(gene name synonym)|uniprotkb:XRN1(gene name)|psi-mi:XRN1(display_short)|uniprotkb:SEP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849966|imex:IM-13779-5410	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR019776|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:WP_002211113.1|interpro:IPR037058|interpro:IPR037925|interpro:IPR053967|refseq:YP_002346797.1"	"ensembl:ENSG00000114127.11(gene)|ensembl:ENST00000264951.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0002151""(G-quadruplex RNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004534""(5'-3' RNA exonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0016075""(rRNA catabolic process)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030425""(dendrite)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0033574""(response to testosterone)|go:""GO:0043025""(neuronal cell body)|go:""GO:0051880""(G-quadruplex DNA binding)|go:""GO:0070034""(telomerase RNA binding)|go:""GO:0071028""(nuclear mRNA surveillance)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:0071409""(cellular response to cycloheximide)|go:""GO:1905795""(cellular response to puromycin)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR016494(5'-3' exoribonuclease 1)|interpro:IPR027073|interpro:IPR040992|interpro:IPR041106|interpro:IPR041385|interpro:IPR041412|interpro:IPR047007|interpro:IPR047008|mint:Q8IZH2|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|refseq:NP_061874.3|refseq:NP_001269786.1|refseq:NP_001269788.1|dip:DIP-31174N|panther:PTHR12341(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:BoYVEh/qtD+LMyJcZpSfUZt9yTk632	rogid:Y5wskamFEhJ+vmrGjlw4nYHiWLg9606	intact-crc:0C6754F2025C1F17|rigid:UVS7FlWd6HpShME96Y93cJzRCEM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YHJ0	uniprotkb:Q8IZH2	intact:EBI-2840822|uniprotkb:A0A384KBR7|uniprotkb:Q0WCM8|uniprotkb:Q7CJI0	intact:EBI-372406|ensembl:ENSP00000264951.4|uniprotkb:Q4G0S3|uniprotkb:Q68D88|uniprotkb:Q6AI24|uniprotkb:Q6MZS8|uniprotkb:Q86WS7|uniprotkb:Q8N8U4|uniprotkb:Q9UF39	psi-mi:a0a5p8yhj0_yerpe(display_long)|uniprotkb:napF(gene name)|psi-mi:napF(display_short)|uniprotkb:YPO3040(locus name)	psi-mi:xrn1_human(display_long)|uniprotkb:Strand-exchange protein 1 homolog(gene name synonym)|uniprotkb:XRN1(gene name)|psi-mi:XRN1(display_short)|uniprotkb:SEP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849959|imex:IM-13779-5408	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR004496(Ferredoxin-type protein NapF)|refseq:YP_002347960.1|interpro:IPR017900|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002208536.1|interpro:IPR050572|panther:PTHR24960(orthology-group)"	"ensembl:ENSG00000114127.11(gene)|ensembl:ENST00000264951.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0002151""(G-quadruplex RNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004534""(5'-3' RNA exonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0016020""(membrane)|go:""GO:0016075""(rRNA catabolic process)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030425""(dendrite)|go:""GO:0032211""(negative regulation of telomere maintenance via telomerase)|go:""GO:0033574""(response to testosterone)|go:""GO:0043025""(neuronal cell body)|go:""GO:0051880""(G-quadruplex DNA binding)|go:""GO:0070034""(telomerase RNA binding)|go:""GO:0071028""(nuclear mRNA surveillance)|go:""GO:0071044""(histone mRNA catabolic process)|go:""GO:0071409""(cellular response to cycloheximide)|go:""GO:1905795""(cellular response to puromycin)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR016494(5'-3' exoribonuclease 1)|interpro:IPR027073|interpro:IPR040992|interpro:IPR041106|interpro:IPR041385|interpro:IPR041412|interpro:IPR047007|interpro:IPR047008|mint:Q8IZH2|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|refseq:NP_061874.3|refseq:NP_001269786.1|refseq:NP_001269788.1|dip:DIP-31174N|panther:PTHR12341(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:eff9jqgNqHt/SEUvObWFEj5j/tU632	rogid:Y5wskamFEhJ+vmrGjlw4nYHiWLg9606	intact-crc:5A414BE5922BF9B8|rigid:6eGtuJXfkerax7ts47C+o11Gik4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GWP6	uniprotkb:P55060	intact:EBI-2850003|uniprotkb:Q74T74|uniprotkb:A0A0H2W4U0|uniprotkb:A0A3N4B2Q2|uniprotkb:Q7CJ58|uniprotkb:A0A384LDM1	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|ensembl:ENSP00000262982.2|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904	psi-mi:a0a2u2gwp6_yerpe(display_long)|uniprotkb:rbsA(gene name)|psi-mi:rbsA(display_short)|uniprotkb:YPO2500(locus name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850000|imex:IM-13779-5412	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017871|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_002210222.1|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:YP_002347464.1|interpro:IPR050107"	"ensembl:ENSG00000124207.17(gene)|ensembl:ENST00000262982.3(transcript)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060|refseq:NP_001307.2|refseq:NP_001243064.1|refseq:XP_011526901.1|dip:DIP-32573N|panther:PTHR10997(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:jbjjVUOif2wxFmZHDDj+lIHZRN8632	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	intact-crc:C58E0E69D2FB26C9|rigid:H2toMqsMqek/ZAhioaBEc+yKzkk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAN0	uniprotkb:O43542	intact:EBI-2842242|uniprotkb:Q0WAP3	intact:EBI-2849976|uniprotkb:Q9BU18|uniprotkb:O43568|ensembl:ENSP00000343392.7|ensembl:ENSP00000451362.1|ensembl:ENSP00000451974.1|ensembl:ENSP00000452598.1	psi-mi:fadb_yerpe(display_long)|uniprotkb:fadB(gene name)|psi-mi:fadB(display_short)|uniprotkb:YPO3766(locus name)|uniprotkb:y0464(locus name)|uniprotkb:YP_3282(locus name)	psi-mi:xrcc3_human(display_long)|uniprotkb:XRCC3(gene name)|psi-mi:XRCC3(display_short)|uniprotkb:X-ray repair cross-complementing protein 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849986|imex:IM-13779-5411	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|interpro:IPR012799(Fatty oxidation complex, alpha subunit FadB)|interpro:IPR029045|go:""GO:0004165""(""delta(3)-delta(2)-enoyl-CoA isomerase activity"")|go:""GO:0004300""(enoyl-CoA hydratase activity)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0008692""(3-hydroxybutyryl-CoA epimerase activity)|go:""GO:0016509""(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:""GO:0036125""(fatty acid beta-oxidation multienzyme complex)|go:""GO:0070403""(NAD+ binding)|refseq:WP_002211546.1|interpro:IPR036291|refseq:YP_002348645.1|interpro:IPR050136|panther:PTHR43612(orthology-group)"	"refseq:XP_011535440.1|refseq:NP_001093588.1|refseq:NP_001093589.1|refseq:NP_005423.1|refseq:XP_005268103.1|ensembl:ENSG00000126215.14(gene)|ensembl:ENST00000352127.11(transcript)|ensembl:ENST00000553264.5(transcript)|ensembl:ENST00000554913.5(transcript)|ensembl:ENST00000555055.6(transcript)|go:""GO:0000722""(telomere maintenance via recombination)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005657""(replication fork)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006974""(DNA damage response)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0033065""(Rad51C-XRCC3 complex)|go:""GO:0036297""(interstrand cross-link repair)|go:""GO:0045003""(double-strand break repair via synthesis-dependent strand annealing)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0071140""(resolution of mitotic recombination intermediates)|go:""GO:0090267""(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:""GO:0090656""(t-circle formation)|go:""GO:0090657""(telomeric loop disassembly)|go:""GO:0090737""(telomere maintenance via telomere trimming)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR047348|mint:O43542|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|dip:DIP-42016N|panther:PTHR46487(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:zUCGFSdEv7X+WT+PNMNgwgSM+4c632	rogid:3vDLDeKRnmV6Wg9dK2yMbIRqzVk9606	intact-crc:60953897BE946FA9|rigid:3/EgPRmaBvHa+eBPVe3S+NT6QoY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CKD4	uniprotkb:Q9HAV4	intact:EBI-2840399|uniprotkb:Q74XT5	intact:EBI-517949|uniprotkb:Q5JTE6|uniprotkb:Q96G48|uniprotkb:Q96HN3|uniprotkb:Q9BWM6|uniprotkb:Q9BZV5|uniprotkb:Q9H9M4|uniprotkb:Q9NT89|uniprotkb:Q9NW39|uniprotkb:Q9ULC9|ensembl:ENSP00000265351.7	psi-mi:mtnn_yerpe(display_long)|uniprotkb:mtnN(gene name)|psi-mi:mtnN(display_short)|uniprotkb:5'-methylthioadenosine nucleosidase(gene name synonym)|uniprotkb:S-adenosylhomocysteine nucleosidase(gene name synonym)|uniprotkb:YPO3384(locus name)|uniprotkb:y0805(locus name)|uniprotkb:YP_0301(locus name)|uniprotkb:5'-deoxyadenosine nucleosidase(gene name synonym)	psi-mi:xpo5_human(display_long)|uniprotkb:Ran-binding protein 21(gene name synonym)|uniprotkb:XPO5(gene name)|psi-mi:XPO5(display_short)|uniprotkb:KIAA1291(gene name synonym)|uniprotkb:RANBP21(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849993|imex:IM-13779-5414	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010049(MTA/SAH nucleosidase)|interpro:IPR000845(Nucleoside phosphorylase)|go:""GO:0005829""(cytosol)|go:""GO:0008782""(adenosylhomocysteine nucleosidase activity)|go:""GO:0008930""(methylthioadenosine nucleosidase activity)|go:""GO:0019284""(L-methionine salvage from S-adenosylmethionine)|go:""GO:0019509""(L-methionine salvage from methylthioadenosine)|go:""GO:0046124""(purine deoxyribonucleoside catabolic process)|refseq:WP_002209368.1|refseq:YP_002348276.1|interpro:IPR035994|panther:PTHR46832(orthology-group)"	"refseq:NP_065801.1|ensembl:ENSG00000124571.18(gene)|ensembl:ENST00000265351.12(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0010586""(miRNA metabolic process)|go:""GO:0016442""(RISC complex)|go:""GO:0031267""(small GTPase binding)|go:""GO:0035281""(pre-miRNA export from nucleus)|go:""GO:0042565""(RNA nuclear export complex)|go:""GO:0070883""(pre-miRNA binding)|go:""GO:1905172""(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR045065|interpro:IPR045478|mint:Q9HAV4|rcsb pdb:3A6P|rcsb pdb:5YU6|rcsb pdb:5YU7|reactome:R-HSA-203927|dip:DIP-34547N|panther:PTHR11223(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:B0ee2BpeZO6x/HS8F1N1G7fln3k632	rogid:wuUAxvyCl/u7CRtQLMK9McSoUrM9606	intact-crc:BE28CD3D73FAC72A|rigid:r7F5Xle9YQLNL/tFfUTdAtubCPs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43542	uniprotkb:A0A380PDY1	intact:EBI-2849976|uniprotkb:Q9BU18|uniprotkb:O43568|ensembl:ENSP00000343392.7|ensembl:ENSP00000451362.1|ensembl:ENSP00000451974.1|ensembl:ENSP00000452598.1	intact:EBI-2848416|uniprotkb:Q74UI0|uniprotkb:A0A0H2W558|uniprotkb:Q7CIW0|uniprotkb:A0A384L8E0	psi-mi:xrcc3_human(display_long)|uniprotkb:XRCC3(gene name)|psi-mi:XRCC3(display_short)|uniprotkb:X-ray repair cross-complementing protein 3(gene name synonym)	psi-mi:a0a380pdy1_yerpe(display_long)|uniprotkb:ogl(gene name)|psi-mi:ogl(display_short)|uniprotkb:YPO1713(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2849973|imex:IM-13779-5415	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011535440.1|refseq:NP_001093588.1|refseq:NP_001093589.1|refseq:NP_005423.1|refseq:XP_005268103.1|ensembl:ENSG00000126215.14(gene)|ensembl:ENST00000352127.11(transcript)|ensembl:ENST00000553264.5(transcript)|ensembl:ENST00000554913.5(transcript)|ensembl:ENST00000555055.6(transcript)|go:""GO:0000722""(telomere maintenance via recombination)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005657""(replication fork)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0006281""(DNA repair)|go:""GO:0006310""(DNA recombination)|go:""GO:0006974""(DNA damage response)|go:""GO:0010824""(regulation of centrosome duplication)|go:""GO:0033065""(Rad51C-XRCC3 complex)|go:""GO:0036297""(interstrand cross-link repair)|go:""GO:0045003""(double-strand break repair via synthesis-dependent strand annealing)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0071140""(resolution of mitotic recombination intermediates)|go:""GO:0090267""(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:""GO:0090656""(t-circle formation)|go:""GO:0090657""(telomeric loop disassembly)|go:""GO:0090737""(telomere maintenance via telomere trimming)|go:""GO:0140664""(ATP-dependent DNA damage sensor activity)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR047348|mint:O43542|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|dip:DIP-42016N|panther:PTHR46487(orthology-group)"	"interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027946|refseq:WP_002210841.1|go:""GO:0045490""(pectin catabolic process)|go:""GO:0047487""(oligogalacturonide lyase activity)|refseq:YP_002346716.1|panther:PTHR36842(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:3vDLDeKRnmV6Wg9dK2yMbIRqzVk9606	rogid:e8mn+xTHxqbWMCnpEvzfGUD7MYI632	intact-crc:8A3AC87FBEAE0AEB|rigid:QPIb3v9MsGJWRC3d2SCo/MVMxE0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YAM6	uniprotkb:P55060	intact:EBI-2844150|uniprotkb:Q7CFP2|uniprotkb:Q0W9V4	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|ensembl:ENSP00000262982.2|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904	psi-mi:a0a5p8yam6_yerpe(display_long)|uniprotkb:malS(gene name)|psi-mi:malS(display_short)|uniprotkb:YPO4080(locus name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850012|imex:IM-13779-5413	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014635(Alpha-amylase, MalS type)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:WP_002209631.1|go:""GO:0004556""(alpha-amylase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0009313""(oligosaccharide catabolic process)|go:""GO:0030980""(alpha-glucan catabolic process)|go:""GO:0042597""(periplasmic space)|refseq:YP_002348934.1|panther:PTHR10357(orthology-group)"	"ensembl:ENSG00000124207.17(gene)|ensembl:ENST00000262982.3(transcript)|go:""GO:0005049""(nuclear export signal receptor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0016020""(membrane)|go:""GO:0031267""(small GTPase binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060|refseq:NP_001307.2|refseq:NP_001243064.1|refseq:XP_011526901.1|dip:DIP-32573N|panther:PTHR10997(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:qjQekYtSF56tT51Uzp+xShmXohk632	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	intact-crc:3F7C2F3A95B2CA3F|rigid:TGh+KFU+lsBc/69NNrJd84C0j8M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H0M0	uniprotkb:Q8ZD41	intact:EBI-742157|uniprotkb:O00307|uniprotkb:Q96BP4|uniprotkb:Q5YLC1|ensembl:ENSP00000265428.4|ensembl:ENSP00000427793.1	intact:EBI-2850034|uniprotkb:Q0WDE0	psi-mi:wwp1_human(display_long)|uniprotkb:WWP1(gene name)|psi-mi:WWP1(display_short)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 5(gene name synonym)|uniprotkb:TGIF-interacting ubiquitin ligase 1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase WWP1(gene name synonym)	psi-mi:aroc_yerpe(display_long)|uniprotkb:aroC(gene name)|psi-mi:aroC(display_short)|uniprotkb:5-enolpyruvylshikimate-3-phosphate phospholyase(gene name synonym)|uniprotkb:YPO2751(locus name)|uniprotkb:y1585(locus name)|uniprotkb:YP_2412(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850031|imex:IM-13779-5419	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_008944.1|refseq:XP_005250817.1|ensembl:ENSG00000123124.14(gene)|ensembl:ENST00000265428.4(transcript)|ensembl:ENST00000517970.6(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007165""(signal transduction)|go:""GO:0007417""(central nervous system development)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0034220""(monoatomic ion transmembrane transport)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070161""(anchoring junction)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|interpro:IPR050409|mint:Q9H0M0|rcsb pdb:1ND7|rcsb pdb:2OP7|rcsb pdb:5HPS|rcsb pdb:5HPT|rcsb pdb:6J1X|rcsb pdb:6J1Y|rcsb pdb:8EI4|rcsb pdb:9EQK|reactome:R-HSA-1253288|reactome:R-HSA-2672351|reactome:R-HSA-8939902|reactome:R-HSA-983168|panther:PTHR11254(orthology-group)"	"interpro:IPR000453(Chorismate synthase)|interpro:IPR020541|refseq:WP_002209711.1|go:""GO:0004107""(chorismate synthase activity)|go:""GO:0005829""(cytosol)|go:""GO:0008652""(amino acid biosynthetic process)|go:""GO:0009073""(aromatic amino acid family biosynthetic process)|go:""GO:0009423""(chorismate biosynthetic process)|go:""GO:0010181""(FMN binding)|interpro:IPR035904|refseq:YP_002347698.1|panther:PTHR21085(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:a+aRHHhwu3pCkmlkDNqcN1PJ7LI9606	rogid:JiOF5E6AsFilf6hnLfD+ulllk60632	intact-crc:ABB01F04253B4611|rigid:4lCyIEaVDQAso/UBXeKpAcZvSKg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HCN4	uniprotkb:A0A2U2GYT1	intact:EBI-745137|uniprotkb:O76004|uniprotkb:B4DQJ5|uniprotkb:B4DXU4|uniprotkb:B4DQM4|uniprotkb:B5MBZ5|ensembl:ENSP00000476446.1	intact:EBI-2850019|uniprotkb:Q74UX9|uniprotkb:A0A5P8YEY5|uniprotkb:A0A0H2W327|uniprotkb:Q7CHZ4|uniprotkb:A0A384L0J7	psi-mi:gpn1_human(display_long)|uniprotkb:XAB1(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:GPN1(gene name)|psi-mi:GPN1(display_short)|uniprotkb:MBDIN(gene name synonym)|uniprotkb:HUSSY-23(orf name)|uniprotkb:RNAPII-associated protein 4(gene name synonym)|uniprotkb:RPAP4(gene name synonym)	psi-mi:a0a2u2gyt1_yerpe(display_long)|uniprotkb:fla AII.2(gene name)|psi-mi:fla AII.2(display_short)|uniprotkb:fla BII(gene name synonym)|uniprotkb:fliG(gene name synonym)|uniprotkb:YPO1829(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850024|imex:IM-13779-5416	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001138519.1|refseq:NP_001138520.1|refseq:NP_001138521.1|refseq:NP_009197.2|ensembl:ENSG00000198522.14(gene)|ensembl:ENST00000610189.2(transcript)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|mint:Q9HCN4|panther:PTHR21231(orthology-group)"	"interpro:IPR023087|interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR028263|refseq:WP_002211142.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:YP_002346825.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QZOTFh9d1hOcoG1DxAueYEwbOpc9606	rogid:YBRmcuS18DJP2sfWEnw15dGyeYk632	intact-crc:15E232D8955298D3|rigid:nh/gWnOndTHZa0iRXswUgilGO3M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96S55	uniprotkb:Q7ARD3	intact:EBI-2513471|uniprotkb:Q9NRJ6|uniprotkb:Q5W0E2|uniprotkb:Q53EP6|uniprotkb:Q8WV26|uniprotkb:Q5W0E4|uniprotkb:Q59ET8|uniprotkb:Q9H681|uniprotkb:B2RDB0|ensembl:ENSP00000370150.4|ensembl:ENSP00000477551.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:wrip1_human(display_long)|uniprotkb:WRNIP1(gene name)|psi-mi:WRNIP1(display_short)|uniprotkb:WHIP(gene name synonym)|uniprotkb:Werner helicase-interacting protein 1(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850054|imex:IM-13779-5418	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000124535.16(gene)|ensembl:ENST00000380773.9(transcript)|ensembl:ENST00000618555.4(transcript)|go:""GO:0000731""(DNA synthesis involved in DNA repair)|go:""GO:0003677""(DNA binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0008047""(enzyme activator activity)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017116""(single-stranded DNA helicase activity)|go:""GO:0030174""(regulation of DNA-templated DNA replication initiation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|interpro:IPR040539|interpro:IPR051314|mint:Q96S55|rcsb pdb:3VHS|rcsb pdb:3VHT|refseq:NP_064520.2|refseq:NP_569079.1|panther:PTHR13779(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Q8qVSqItgTO7sbWGAQ3XAoFFUr89606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:D5C8BC62B50E2626|rigid:wjbCTAfKRUMXLsghr4Fn/e37OVY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14191	uniprotkb:A0A5P8YJ66	intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139.5	intact:EBI-2850046|uniprotkb:Q74RM6|uniprotkb:A0A2U2H1F0|uniprotkb:A0A0H2W677|uniprotkb:Q7CGI7|uniprotkb:A0A384KU41	psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym)|uniprotkb:Werner syndrome protein(gene name synonym)	psi-mi:a0a5p8yj66_yerpe(display_long)|uniprotkb:YPO0684(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850043|imex:IM-13779-5417	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:902""|ensembl:ENSG00000165392.11(gene)|ensembl:ENST00000298139.7(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000400""(four-way junction DNA binding)|go:""GO:0000403""(Y-form DNA binding)|go:""GO:0000405""(bubble DNA binding)|go:""GO:0000723""(telomere maintenance)|go:""GO:0000724""(double-strand break repair via homologous recombination)|go:""GO:0000731""(DNA synthesis involved in DNA repair)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003677""(DNA binding)|go:""GO:0003678""(DNA helicase activity)|go:""GO:0003682""(chromatin binding)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005657""(replication fork)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0006259""(DNA metabolic process)|go:""GO:0006260""(DNA replication)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0006284""(base-excision repair)|go:""GO:0006302""(double-strand break repair)|go:""GO:0006974""(DNA damage response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0008340""(determination of adult lifespan)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0010225""(response to UV-C)|go:""GO:0016607""(nuclear speck)|go:""GO:0016853""(isomerase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030145""(manganese ion binding)|go:""GO:0031297""(replication fork processing)|go:""GO:0032201""(telomere maintenance via semi-conservative replication)|go:""GO:0032405""(MutLalpha complex binding)|go:""GO:0032508""(obsolete DNA duplex unwinding)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0040009""(regulation of growth rate)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043138""(3'-5' DNA helicase activity)|go:""GO:0044806""(obsolete G-quadruplex DNA unwinding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0051345""(positive regulation of hydrolase activity)|go:""GO:0051880""(G-quadruplex DNA binding)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0061820""(telomeric D-loop disassembly)|go:""GO:0061821""(telomeric D-loop binding)|go:""GO:0061849""(telomeric G-quadruplex DNA binding)|go:""GO:0070337""(3'-flap-structured DNA binding)|go:""GO:0071480""(cellular response to gamma radiation)|go:""GO:0090398""(cellular senescence)|go:""GO:0090399""(replicative senescence)|go:""GO:0090656""(t-circle formation)|go:""GO:0098530""(positive regulation of strand invasion)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|go:""GO:1902570""(protein localization to nucleolus)|go:""GO:1905773""(8-hydroxy-2'-deoxyguanosine DNA binding)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|interpro:IPR044876|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|rcsb pdb:2FBY|rcsb pdb:2FC0|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|rcsb pdb:7GQS|rcsb pdb:7GQT|rcsb pdb:7GQU|rcsb pdb:7XUT|rcsb pdb:8PFL|rcsb pdb:8PFO|rcsb pdb:8PFP|rcsb pdb:8YLE|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9701192|reactome:R-HSA-9704331|reactome:R-HSA-9704646|reactome:R-HSA-9709570|reactome:R-HSA-9709603|refseq:NP_000544.2|dip:DIP-31380N|panther:PTHR13710(orthology-group)"	refseq:WP_002212169.1|interpro:IPR036465|refseq:YP_002345750.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/27	rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606	rogid:KizmEigIJwb1SmlvV0RiTRhkoTQ632	intact-crc:DCA443D97B4D8078|rigid:w++vLC3yueXGy+TA4E4LFLfgNpI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y3S1	uniprotkb:Q8D1P4	intact:EBI-948521|uniprotkb:Q8IY36|uniprotkb:Q9C0A3|uniprotkb:Q9H3P4|uniprotkb:Q5VWF1|uniprotkb:Q5VWF2|ensembl:ENSP00000297954.4	intact:EBI-2845144	psi-mi:wnk2_human(display_long)|uniprotkb:Protein kinase with no lysine 2(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 2(gene name synonym)|uniprotkb:Serologically defined colon cancer antigen 43(gene name synonym)|uniprotkb:Antigen NY-CO-43(gene name synonym)|uniprotkb:WNK2(gene name)|psi-mi:WNK2(display_short)|uniprotkb:KIAA1760(gene name synonym)|uniprotkb:PRKWNK2(gene name synonym)|uniprotkb:P/OKcl.13(orf name)|uniprotkb:SDCCAG43(gene name synonym)	psi-mi:q8d1p4_yerpe(display_long)|uniprotkb:y0195(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850061|imex:IM-13779-5420	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165238.17(gene)|ensembl:ENST00000297954.9(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0050801""(monoatomic ion homeostasis)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:2000651""(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|interpro:IPR050588|rcsb pdb:6ELM|rcsb pdb:6FBK|reactome:R-HSA-2672351|refseq:NP_001269323.1|refseq:XP_005252197.1|panther:PTHR24361(orthology-group)"	interpro:IPR032712|interpro:IPR025263|interpro:IPR011836(Conserved hypothetical protein CHP02099)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+Q63ncfKZnhhD2F9FQY1iX3ObCc9606	rogid:k1ALZgWrTdqeyJ1mZBZgusKWD8Y632	intact-crc:4C04A9496565540C|rigid:Sxb2HlabfqY7PP1XF/Jd0UkUSRM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0B2	uniprotkb:O76076	intact:EBI-2850083|uniprotkb:Q74UX8	intact:EBI-2850068|uniprotkb:B2R9N4|uniprotkb:E1P612|uniprotkb:Q6PEG3|ensembl:ENSP00000190983.4|ensembl:ENSP00000361959.2	psi-mi:q8d0b2_yerpe(display_long)|uniprotkb:fliH(gene name)|psi-mi:fliH(display_short)|uniprotkb:fliH1(gene name synonym)|uniprotkb:YP_1564(locus name)|uniprotkb:y2478(locus name)	psi-mi:ccn5_human(display_long)|uniprotkb:CT58(gene name synonym)|uniprotkb:CTGFL(gene name synonym)|uniprotkb:Connective tissue growth factor-like protein(gene name synonym)|uniprotkb:Connective tissue growth factor-related protein 58(gene name synonym)|uniprotkb:WISP2(gene name synonym)|uniprotkb:CCN5(gene name)|psi-mi:CCN5(display_short)|uniprotkb:WNT1-inducible-signaling pathway protein 2(gene name synonym)|uniprotkb:UNQ228/PRO261(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850080|imex:IM-13779-5421	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000563(Flagellar assembly protein FliH)|interpro:IPR018035|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0009288""(bacterial-type flagellum)|go:""GO:0015031""(protein transport)|go:""GO:0044781""(bacterial-type flagellum organization)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR051472"	"refseq:NP_001310298.1|refseq:NP_001310299.1|refseq:NP_003872.1|ensembl:ENSG00000064205.11(gene)|ensembl:ENST00000190983.5(transcript)|ensembl:ENST00000372868.6(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0045597""(positive regulation of cell differentiation)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017891|interpro:IPR036383|interpro:IPR043973|interpro:IPR050941|panther:PTHR11348(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pu9m0K/LYZp0hFWjqupRjpJzuhQ632	rogid:NKQyb5z8vhNDIngy6OoFkvjzUCM9606	intact-crc:F8B99B47F9A144DA|rigid:5bhK5/58QTaICveVuYQVSrQQTyE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H345	uniprotkb:Q8TF74	intact:EBI-2850104|uniprotkb:Q74RR9|uniprotkb:Q0WJ38|uniprotkb:Q7CGG1|uniprotkb:A0A384LCZ1	intact:EBI-2850112|uniprotkb:Q8TE44|uniprotkb:A8K0L3|uniprotkb:Q658J8|uniprotkb:Q71RE1|ensembl:ENSP00000320924.4|ensembl:ENSP00000462350.1|ensembl:ENSP00000462826.1	psi-mi:a0a2u2h345_yerpe(display_long)|uniprotkb:YPO0631(locus name)	psi-mi:wipf2_human(display_long)|uniprotkb:WIPF2(gene name)|psi-mi:WIPF2(display_short)|uniprotkb:WICH(gene name synonym)|uniprotkb:WIRE(gene name synonym)|uniprotkb:WASP-interacting protein-related protein(gene name synonym)|uniprotkb:WIP- and CR16-homologous protein(gene name synonym)|uniprotkb:WIP-related protein(gene name synonym)|uniprotkb:PP10631(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850109|imex:IM-13779-5424	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005119(LysR, substrate-binding)|interpro:IPR000847(Bacterial regulatory protein, LysR)|refseq:WP_002210366.1|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0043565""(sequence-specific DNA binding)|interpro:IPR036388|interpro:IPR036390|refseq:YP_002345700.1|panther:PTHR30537(orthology-group)"	"refseq:XP_011522715.1|refseq:NP_573571.1|refseq:XP_005257140.1|refseq:XP_005257141.1|ensembl:ENSG00000171475.14(gene)|ensembl:ENST00000323571.9(transcript)|ensembl:ENST00000583130.5(transcript)|ensembl:ENST00000585043.5(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|interpro:IPR003124(Actin-binding WH2)|mint:Q8TF74|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9MuOK3XVpDs6AFFvWa9cobxDtA0632	rogid:xnXvZLySNsfyWjL2lkAMUH16hlU9606	intact-crc:D485FAFA5ECAE40B|rigid:7Of00ZZwe6vMNmLXzy0ILcrdKm8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJF3	uniprotkb:Q9Y4P8	intact:EBI-2850095|uniprotkb:Q0WKE6	intact:EBI-719396|uniprotkb:Q5MNZ8|uniprotkb:Q6FI96|uniprotkb:Q75L50|uniprotkb:Q96IE4|uniprotkb:Q9Y364|uniprotkb:B3KNC2|ensembl:ENSP00000288828.4	psi-mi:gph_yerpe(display_long)|uniprotkb:gph(gene name)|psi-mi:gph(display_short)|uniprotkb:YPO0156(locus name)|uniprotkb:y3939(locus name)|uniprotkb:YP_0158(locus name)	psi-mi:wipi2_human(display_long)|uniprotkb:WIPI49-like protein 2(gene name synonym)|uniprotkb:WIPI2(gene name)|psi-mi:WIPI2(display_short)|uniprotkb:CGI-50(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850092|imex:IM-13779-5422	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|interpro:IPR037512|refseq:WP_002208892.1|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006281""(DNA repair)|go:""GO:0008967""(phosphoglycolate phosphatase activity)|go:""GO:0046295""(glycolate biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR036412|interpro:IPR041492|refseq:YP_002345242.1|interpro:IPR050155|panther:PTHR43434(orthology-group)"	"refseq:NP_001028690.1|refseq:NP_001028691.1|refseq:NP_001028692.1|refseq:NP_056425.1|refseq:NP_057087.2|ensembl:ENSG00000157954.15(gene)|ensembl:ENST00000288828.9(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0000422""(autophagy of mitochondrion)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0010314""(phosphatidylinositol-5-phosphate binding)|go:""GO:0032266""(phosphatidylinositol-3-phosphate binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0034497""(protein localization to phagophore assembly site)|go:""GO:0044804""(nucleophagy)|go:""GO:0061723""(glycophagy)|go:""GO:0080025""(phosphatidylinositol-3,5-bisphosphate binding)|go:""GO:0098792""(xenophagy)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR048720|mint:Q9Y4P8|rcsb pdb:7F69|rcsb pdb:7MU2|rcsb pdb:7XFR|reactome:R-HSA-1632852|refseq:NP_001265228.1|panther:PTHR11227(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:n2m9iPEoLBOpfauijcWx/W/lq+M632	rogid:IKOg7KzZAI2jyK5KsGAz6SOd4XM9606	intact-crc:C78E2CBA7C6B0B9E|rigid:qoSOoAgnL1rEZ+FVhChYp0gNTNs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZY7	uniprotkb:O76076	intact:EBI-2842279|uniprotkb:Q0WI10|uniprotkb:Q8ZH74	intact:EBI-2850068|uniprotkb:B2R9N4|uniprotkb:E1P612|uniprotkb:Q6PEG3|ensembl:ENSP00000190983.4|ensembl:ENSP00000361959.2	psi-mi:sydp_yerpe(display_long)|uniprotkb:syd(gene name)|psi-mi:syd(display_short)|uniprotkb:YPO1035(locus name)|uniprotkb:y3146(locus name)|uniprotkb:YP_2816(locus name)	psi-mi:ccn5_human(display_long)|uniprotkb:CT58(gene name synonym)|uniprotkb:CTGFL(gene name synonym)|uniprotkb:Connective tissue growth factor-like protein(gene name synonym)|uniprotkb:Connective tissue growth factor-related protein 58(gene name synonym)|uniprotkb:WISP2(gene name synonym)|uniprotkb:CCN5(gene name)|psi-mi:CCN5(display_short)|uniprotkb:WNT1-inducible-signaling pathway protein 2(gene name synonym)|uniprotkb:UNQ228/PRO261(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850073|imex:IM-13779-5423	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009948(Syd)|interpro:IPR038228|go:""GO:0009898""(cytoplasmic side of plasma membrane)|refseq:WP_002212123.1|refseq:YP_002346078.1"	"refseq:NP_001310298.1|refseq:NP_001310299.1|refseq:NP_003872.1|ensembl:ENSG00000064205.11(gene)|ensembl:ENST00000190983.5(transcript)|ensembl:ENST00000372868.6(transcript)|go:""GO:0005178""(integrin binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0007155""(cell adhesion)|go:""GO:0007165""(signal transduction)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008201""(heparin binding)|go:""GO:0031012""(extracellular matrix)|go:""GO:0045597""(positive regulation of cell differentiation)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017891|interpro:IPR036383|interpro:IPR043973|interpro:IPR050941|panther:PTHR11348(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:MC0GRav9hd62E9fkiCF0MQ5eBt4632	rogid:NKQyb5z8vhNDIngy6OoFkvjzUCM9606	intact-crc:C08DA310F8899E2B|rigid:94pzoWPXYD6sP+9qM2WJO/NUOr0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43516	uniprotkb:A0A380PHU4	intact:EBI-346356|uniprotkb:Q15220|uniprotkb:Q6MZU9|uniprotkb:Q9BU37|uniprotkb:Q9UNP1|uniprotkb:Q53TA9|uniprotkb:B8ZZM1|uniprotkb:D3DPE4|ensembl:ENSP00000352802.3|ensembl:ENSP00000376329.2|ensembl:ENSP00000376330.2|ensembl:ENSP00000388454.2|ensembl:ENSP00000503603.1|ensembl:ENSP00000513869.1|ensembl:ENSP00000513882.1	intact:EBI-2850134|uniprotkb:Q0WKS5|uniprotkb:Q7CG26	psi-mi:wipf1_human(display_long)|uniprotkb:WIPF1(gene name)|psi-mi:WIPF1(display_short)|uniprotkb:WIP(gene name synonym)|uniprotkb:Wiskott-Aldrich syndrome protein-interacting protein(gene name synonym)|uniprotkb:Protein PRPL-2(gene name synonym)|uniprotkb:WASPIP(gene name synonym)	psi-mi:a0a380phu4_yerpe(display_long)|uniprotkb:resA(gene name synonym)|uniprotkb:polA(gene name)|psi-mi:polA(display_short)|uniprotkb:YPO0017(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850131|imex:IM-13779-5425	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-17015N|panther:PTHR48226(orthology-group)|efo:""Orphanet:906""|ensembl:ENSG00000115935.19(gene)|ensembl:ENST00000359761.7(transcript)|ensembl:ENST00000392546.6(transcript)|ensembl:ENST00000392547.6(transcript)|ensembl:ENST00000436221.2(transcript)|ensembl:ENST00000679041.1(transcript)|ensembl:ENST00000698668.1(transcript)|ensembl:ENST00000698701.1(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051707""(response to other organism)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR053099|mint:O43516|rcsb pdb:2A41|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9664422|refseq:NP_001070737.1|refseq:NP_003378.3|refseq:XP_011510082.1"	"interpro:IPR043502|interpro:IPR019760|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR020046|interpro:IPR020045|interpro:IPR002421(5'-3' exonuclease)|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR018320|interpro:IPR002298(DNA polymerase A)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR029060|refseq:WP_002213164.1|go:""GO:0003677""(DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0006302""(double-strand break repair)|go:""GO:0008408""(3'-5' exonuclease activity)|go:""GO:0008409""(5'-3' exonuclease activity)|interpro:IPR036279|interpro:IPR036397|refseq:YP_002345113.1|panther:PTHR10133(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/10	rogid:8qaxT2n0EXIVTi08xHsryCSSt9k9606	rogid:GygvBdt3VDWoMhC9L9UZrpc6vy0632	intact-crc:6C3FDB688CFB9545|rigid:dMI0ilNV2elxSlfGT0q27J7iLkg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZMY6	uniprotkb:P17778	intact:EBI-2799773|uniprotkb:Q8NEF8|ensembl:ENSP00000348129.2	intact:EBI-2842665|uniprotkb:O68701	psi-mi:wdr88_human(display_long)|uniprotkb:PQWD(gene name synonym)|uniprotkb:PQQ repeat and WD repeat-containing protein(gene name synonym)|uniprotkb:WDR88(gene name)|psi-mi:WDR88(display_short)	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850155|imex:IM-13779-5426	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_775750.3|ensembl:ENSG00000166359.11(gene)|ensembl:ENST00000355868.4(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018391|interpro:IPR019775|interpro:IPR020472|panther:PTHR45048(orthology-group)	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2wNa6tEuHWCmJUafHOpgDT4kp789606	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	intact-crc:7ADA9EAFB390F793|rigid:0eigrSuN6ufLWBhi2SXH8I7BDKU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YKW4	uniprotkb:Q6ZMY6	intact:EBI-2850165	intact:EBI-2799773|uniprotkb:Q8NEF8|ensembl:ENSP00000348129.2	psi-mi:a0a5p8ykw4_yerpe(display_long)|uniprotkb:YP_3671(locus name)|uniprotkb:y3665(locus name)	psi-mi:wdr88_human(display_long)|uniprotkb:PQWD(gene name synonym)|uniprotkb:PQQ repeat and WD repeat-containing protein(gene name synonym)|uniprotkb:WDR88(gene name)|psi-mi:WDR88(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850162|imex:IM-13779-5430	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001646(Pentapeptide repeat)|interpro:IPR018683|refseq:WP_002224087.1|uniprotkb:A0A6B3T2Z3(uniprot-removed-ac)|interpro:IPR052949	refseq:NP_775750.3|ensembl:ENSG00000166359.11(gene)|ensembl:ENST00000355868.4(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018391|interpro:IPR019775|interpro:IPR020472|panther:PTHR45048(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3NJSaWlDR7yCRld+Bz8Son5hdFQ632	rogid:2wNa6tEuHWCmJUafHOpgDT4kp789606	intact-crc:5158C7E057F3A251|rigid:fJw2Mdps0I/D5mVIOpm1BenmD/I	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BRP8	uniprotkb:Q8ZCQ2	intact:EBI-2352802|ensembl:ENSP00000386156.2|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5	intact:EBI-2850142|uniprotkb:Q0WCY7	psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym)	psi-mi:pur4_yerpe(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:YPO2921(locus name)|uniprotkb:YP_2536(locus name)|uniprotkb:y1309(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850148|imex:IM-13779-5429	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000170473.17(gene)|ensembl:ENST00000408946.7(transcript)|go:""GO:0000184""(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0030054""(cell junction)|go:""GO:0035145""(exon-exon junction complex)|go:""GO:0043022""(ribosome binding)|go:""GO:0045727""(positive regulation of translation)|go:""GO:1903259""(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8|refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|panther:PTHR22959(orthology-group)"	"interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR029062|refseq:WP_002211561.1|interpro:IPR040707|go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609|refseq:YP_002347851.1|panther:PTHR10099(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/27	rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606	rogid:8JTbD5hWDWC5PK7sHtiOwqqdyHs632	intact-crc:5CF0D132FBE7C97C|rigid:R7MrnbzX5ACTEfEeuv8zTavr7yg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYS8	uniprotkb:O43516	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	intact:EBI-346356|uniprotkb:Q15220|uniprotkb:Q6MZU9|uniprotkb:Q9BU37|uniprotkb:Q9UNP1|uniprotkb:Q53TA9|uniprotkb:B8ZZM1|uniprotkb:D3DPE4|ensembl:ENSP00000352802.3|ensembl:ENSP00000376329.2|ensembl:ENSP00000376330.2|ensembl:ENSP00000388454.2|ensembl:ENSP00000503603.1|ensembl:ENSP00000513869.1|ensembl:ENSP00000513882.1	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	psi-mi:wipf1_human(display_long)|uniprotkb:WIPF1(gene name)|psi-mi:WIPF1(display_short)|uniprotkb:WIP(gene name synonym)|uniprotkb:Wiskott-Aldrich syndrome protein-interacting protein(gene name synonym)|uniprotkb:Protein PRPL-2(gene name synonym)|uniprotkb:WASPIP(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850124|imex:IM-13779-5428	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	"dip:DIP-17015N|panther:PTHR48226(orthology-group)|efo:""Orphanet:906""|ensembl:ENSG00000115935.19(gene)|ensembl:ENST00000359761.7(transcript)|ensembl:ENST00000392546.6(transcript)|ensembl:ENST00000392547.6(transcript)|ensembl:ENST00000436221.2(transcript)|ensembl:ENST00000679041.1(transcript)|ensembl:ENST00000698668.1(transcript)|ensembl:ENST00000698701.1(transcript)|go:""GO:0001726""(ruffle)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005884""(actin filament)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030048""(actin filament-based movement)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0051707""(response to other organism)|go:""GO:0065003""(protein-containing complex assembly)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR053099|mint:O43516|rcsb pdb:2A41|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9664422|refseq:NP_001070737.1|refseq:NP_003378.3|refseq:XP_011510082.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/10	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	rogid:8qaxT2n0EXIVTi08xHsryCSSt9k9606	intact-crc:24B27FA40E092E1C|rigid:UK71u5nhli1MdKq6eWY3lCWs8og	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6ZMY6	uniprotkb:Q7CIZ7	intact:EBI-2799773|uniprotkb:Q8NEF8|ensembl:ENSP00000348129.2	intact:EBI-2843304|uniprotkb:Q74UE8|uniprotkb:A0A384KZ59|uniprotkb:B4X9S5|uniprotkb:A0A0H2W3L1|uniprotkb:A0A5P8YGN2	psi-mi:wdr88_human(display_long)|uniprotkb:PQWD(gene name synonym)|uniprotkb:PQQ repeat and WD repeat-containing protein(gene name synonym)|uniprotkb:WDR88(gene name)|psi-mi:WDR88(display_short)	psi-mi:q7ciz7_yerpe(display_long)|uniprotkb:appA(gene name)|psi-mi:appA(display_short)|uniprotkb:YPO1648(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850173|imex:IM-13779-5427	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_775750.3|ensembl:ENSG00000166359.11(gene)|ensembl:ENST00000355868.4(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018391|interpro:IPR019775|interpro:IPR020472|panther:PTHR45048(orthology-group)	"interpro:IPR033379|interpro:IPR000560(Histidine acid phosphatase)|interpro:IPR029033|go:""GO:0003993""(acid phosphatase activity)|go:""GO:0008707""(4-phytase activity)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0050308""(sugar-phosphatase activity)|refseq:WP_002210903.1|refseq:YP_002346658.1|interpro:IPR050645|panther:PTHR11567(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2wNa6tEuHWCmJUafHOpgDT4kp789606	rogid:LJ8BlvMBlhdzSOKMptIEdIH68xQ632	intact-crc:AF7B00244B8416DF|rigid:1synGI9KzOH2r7fXyE7xaPESTEQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PL72	uniprotkb:Q6ZMY6	intact:EBI-2846035|uniprotkb:Q74PY5|uniprotkb:Q7CG60|uniprotkb:A0A5P8YKG0|uniprotkb:A0A0H2W9Q1	intact:EBI-2799773|uniprotkb:Q8NEF8|ensembl:ENSP00000348129.2	psi-mi:a0a2s9pl72_yerpe(display_long)|uniprotkb:YPO0433(locus name)	psi-mi:wdr88_human(display_long)|uniprotkb:PQWD(gene name synonym)|uniprotkb:PQQ repeat and WD repeat-containing protein(gene name synonym)|uniprotkb:WDR88(gene name)|psi-mi:WDR88(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850187|imex:IM-13779-5431	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|interpro:IPR037483|refseq:WP_002216076.1|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|refseq:YP_002345509.1|interpro:IPR050301|interpro:IPR045943"	refseq:NP_775750.3|ensembl:ENSG00000166359.11(gene)|ensembl:ENST00000355868.4(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018391|interpro:IPR019775|interpro:IPR020472|panther:PTHR45048(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dGGnmUKWsfkWsugTnVXDGTIqto8632	rogid:2wNa6tEuHWCmJUafHOpgDT4kp789606	intact-crc:BEF6573713815C57|rigid:jFxL1bd860ACat0BV11TSHJKwcQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NNW5	uniprotkb:A0A3N4BEU0	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389.1	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	psi-mi:wdr6_human(display_long)|uniprotkb:WD repeat-containing protein 6(gene name synonym)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850194|imex:IM-13779-5434	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060501.3|panther:PTHR14344(orthology-group)|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252.19(gene)|ensembl:ENST00000608424.6(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002130""(wobble position ribose methylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0030488""(tRNA methylation)|go:""GO:0070314""(G1 to G0 transition)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR051973|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	intact-crc:F42F7BAD7BDA1E32|rigid:9mNbPgF0oceeogXdmB2ctVWZBKo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NNW5	uniprotkb:Q8ZJ16	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389.1	intact:EBI-2841852|uniprotkb:Q0WJZ3	psi-mi:wdr6_human(display_long)|uniprotkb:WD repeat-containing protein 6(gene name synonym)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	psi-mi:lexa_yerpe(display_long)|uniprotkb:lexA(gene name)|psi-mi:lexA(display_short)|uniprotkb:YPO0314(locus name)|uniprotkb:y0572(locus name)|uniprotkb:YP_0470(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850208|imex:IM-13779-5433	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060501.3|panther:PTHR14344(orthology-group)|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252.19(gene)|ensembl:ENST00000608424.6(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002130""(wobble position ribose methylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0030488""(tRNA methylation)|go:""GO:0070314""(G1 to G0 transition)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR051973|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273"	"interpro:IPR039418|interpro:IPR006199(LexA DNA-binding region)|interpro:IPR006200(Peptidase S24, LexA repressor)|interpro:IPR006197(Peptidase S24, LexA/MucA/RumA/RuvA)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0009432""(SOS response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002345395.1|refseq:WP_002209090.1|interpro:IPR036286|interpro:IPR036388|interpro:IPR036390|interpro:IPR050077|panther:PTHR33516(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	rogid:1RBPmARbsfVEavq4/r0MVDBH/Og632	intact-crc:FF74310B5CD3A25E|rigid:zoWe6Q80k7k0u6jP8QvIbZrBLuU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PH42	uniprotkb:Q9NNW5	intact:EBI-2843976|uniprotkb:Q7CI41|uniprotkb:A0A3N4B635|uniprotkb:Q0WFN6	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389.1	psi-mi:a0a2s9ph42_yerpe(display_long)|uniprotkb:irp2(gene name)|psi-mi:irp2(display_short)|uniprotkb:YPO1911(locus name)	psi-mi:wdr6_human(display_long)|uniprotkb:WD repeat-containing protein 6(gene name synonym)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850201|imex:IM-13779-5432	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020806|rcsb pdb:7JTJ|rcsb pdb:7JUA|interpro:IPR029063|interpro:IPR010071(Amino acid adenylation)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001242(Condensation domain)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR020845|go:""GO:0003824""(catalytic activity)|go:""GO:0009403""(toxin biosynthetic process)|go:""GO:0031177""(phosphopantetheine binding)|refseq:WP_002212775.1|rcsb pdb:2N6Y|rcsb pdb:2N6Z|rcsb pdb:5U3H|interpro:IPR023213|interpro:IPR036736|rcsb pdb:7RY6|interpro:IPR042099|refseq:YP_002346902.1|interpro:IPR045851"	"refseq:NP_060501.3|panther:PTHR14344(orthology-group)|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252.19(gene)|ensembl:ENST00000608424.6(transcript)|go:""GO:0000049""(tRNA binding)|go:""GO:0002130""(wobble position ribose methylation)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010507""(negative regulation of autophagy)|go:""GO:0030234""(enzyme regulator activity)|go:""GO:0030488""(tRNA methylation)|go:""GO:0070314""(G1 to G0 transition)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR051973|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KfeTeZp+lut8Pzz4JrX7HMjjWS0632	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	intact-crc:A56F83FD05C2E083|rigid:ivby+J7HtXvnAUgTeYHJc5ndQ4g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PC31	uniprotkb:Q6ZMY6	intact:EBI-2847467|uniprotkb:Q74TQ8|uniprotkb:Q7CII9|uniprotkb:Q0WEL8	intact:EBI-2799773|uniprotkb:Q8NEF8|ensembl:ENSP00000348129.2	psi-mi:a0a380pc31_yerpe(display_long)|uniprotkb:pntA(gene name)|psi-mi:pntA(display_short)|uniprotkb:YPO2303(locus name)	psi-mi:wdr88_human(display_long)|uniprotkb:PQWD(gene name synonym)|uniprotkb:PQQ repeat and WD repeat-containing protein(gene name synonym)|uniprotkb:WDR88(gene name)|psi-mi:WDR88(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850180|imex:IM-13779-5435	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026255|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR024605|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|refseq:WP_002211019.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006740""(NADPH regeneration)|go:""GO:0008750""(""proton-translocating NAD(P)+ transhydrogenase activity"")|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0050661""(NADP binding)|interpro:IPR036291|refseq:YP_002347270.1|panther:PTHR10160(orthology-group)"	refseq:NP_775750.3|ensembl:ENSG00000166359.11(gene)|ensembl:ENST00000355868.4(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018391|interpro:IPR019775|interpro:IPR020472|panther:PTHR45048(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FVP+mtiTI6lGXb+9R8nUXq43tEc632	rogid:2wNa6tEuHWCmJUafHOpgDT4kp789606	intact-crc:73F0DFD104C2D63B|rigid:S94sTvwVklh1VMHWV8TIBrIUw8k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PJI9	uniprotkb:A0A3G5LBX8	intact:EBI-2515073|intact:EBI-28967178|uniprotkb:Q9HA43|uniprotkb:Q96PW5|uniprotkb:B3KRC3|uniprotkb:Q9BSW6|uniprotkb:Q71RE7|ensembl:ENSP00000262144.6	intact:EBI-2848086	psi-mi:wdr59_human(display_long)|uniprotkb:WDR59(gene name)|psi-mi:WDR59(display_short)|uniprotkb:KIAA1923(gene name synonym)|uniprotkb:WD repeat-containing protein 59(gene name synonym)|uniprotkb:FP977(orf name)	psi-mi:a0a3g5lbx8_yerpe(display_long)|uniprotkb:y3412(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850215|imex:IM-13779-5436	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_085058.3|ensembl:ENSG00000103091.15(gene)|ensembl:ENST00000262144.11(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005829""(cytosol)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035859""(Seh1-associated complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0061700""(GATOR2 complex)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904263""(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR006575(RWD)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR039456|interpro:IPR049566|interpro:IPR049567|mint:Q6PJI9|rcsb pdb:7UHY|reactome:R-HSA-9639288|refseq:NP_001311100.1|panther:PTHR46170(orthology-group)"	uniprotkb:A0A5P8YIY0(uniprot-removed-ac)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR010071(Amino acid adenylation)|interpro:IPR020845|interpro:IPR036736|interpro:IPR042099|interpro:IPR045851|refseq:WP_002214915.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7yMOhbv8kjVuL8I+Zs+8fLF933k9606	rogid:nRnMFya58I5DJrYEbqwkzL8Fl6o632	intact-crc:340F5C9BFC62F765|rigid:16KKQHa6xuU88nxU5M7VuWq3eZc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLP4	uniprotkb:O75083	intact:EBI-2850239	intact:EBI-351917|uniprotkb:O75313|uniprotkb:Q8N6E5|uniprotkb:Q9UG05|uniprotkb:Q9UG78|uniprotkb:A8MPU4|uniprotkb:Q9UQE0|uniprotkb:A8K6E9|ensembl:ENSP00000427687.1|ensembl:ENSP00000514593.1	psi-mi:q8clp4_yerpe(display_long)|uniprotkb:NCTC5923_00832(orf name)|uniprotkb:y0711(locus name)	psi-mi:wdr1_human(display_long)|uniprotkb:WDR1(gene name)|psi-mi:WDR1(display_short)|uniprotkb:Actin-interacting protein 1(gene name synonym)|uniprotkb:NORI-1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850242|imex:IM-13779-5438	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008397(Alginate lyase)|interpro:IPR008929(Chondroitin AC/alginate lyase)|go:""GO:0016829""(lyase activity)|go:""GO:0042597""(periplasmic space)"	"efo:""Orphanet:652522""|ensembl:ENSG00000071127.18(gene)|ensembl:ENST00000499869.7(transcript)|ensembl:ENST00000699787.1(transcript)|go:""GO:0002102""(podosome)|go:""GO:0002446""(neutrophil mediated immunity)|go:""GO:0005576""(extracellular region)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005911""(cell-cell junction)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0030042""(actin filament depolymerization)|go:""GO:0030043""(actin filament fragmentation)|go:""GO:0030054""(cell junction)|go:""GO:0030220""(platelet formation)|go:""GO:0030834""(regulation of actin filament depolymerization)|go:""GO:0030836""(positive regulation of actin filament depolymerization)|go:""GO:0030864""(cortical actin cytoskeleton)|go:""GO:0030865""(cortical cytoskeleton organization)|go:""GO:0040011""(locomotion)|go:""GO:0042247""(establishment of planar polarity of follicular epithelium)|go:""GO:0042995""(cell projection)|go:""GO:0043297""(apical junction assembly)|go:""GO:0045199""(maintenance of epithelial cell apical/basal polarity)|go:""GO:0045214""(sarcomere organization)|go:""GO:0048713""(regulation of oligodendrocyte differentiation)|go:""GO:0051015""(actin filament binding)|go:""GO:0060307""(regulation of ventricular cardiac muscle cell membrane repolarization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:1990266""(neutrophil migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O75083|reactome:R-HSA-114608|refseq:NP_005103.2|refseq:NP_059830.1|panther:PTHR19856(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:vvNui4Osjg4fo2JFHVcvJdsqBMc632	rogid:ewKq6uA2Wrg/uK31ayOoenA9Gv49606	intact-crc:90454C46167A12FA|rigid:PCjAD63DousgtjrSIlWdSpfcxmI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PJI9	uniprotkb:A0A3N4B6L4	intact:EBI-2515073|intact:EBI-28967178|uniprotkb:Q9HA43|uniprotkb:Q96PW5|uniprotkb:B3KRC3|uniprotkb:Q9BSW6|uniprotkb:Q71RE7|ensembl:ENSP00000262144.6	intact:EBI-2843521|uniprotkb:Q74R92|uniprotkb:Q0WAE3|uniprotkb:Q7CKZ2|uniprotkb:A0A384KL30	psi-mi:wdr59_human(display_long)|uniprotkb:WDR59(gene name)|psi-mi:WDR59(display_short)|uniprotkb:KIAA1923(gene name synonym)|uniprotkb:WD repeat-containing protein 59(gene name synonym)|uniprotkb:FP977(orf name)	psi-mi:a0a3n4b6l4_yerpe(display_long)|uniprotkb:psuA(gene name synonym)|uniprotkb:rnsC(gene name synonym)|uniprotkb:sbaA(gene name synonym)|uniprotkb:tsu(gene name synonym)|uniprotkb:ATP-dependent helicase Rho(gene name synonym)|uniprotkb:rho(gene name synonym)|uniprotkb:nitA(gene name)|psi-mi:nitA(display_short)|uniprotkb:YPO3867(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850222|imex:IM-13779-5439	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_085058.3|ensembl:ENSG00000103091.15(gene)|ensembl:ENST00000262144.11(transcript)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005829""(cytosol)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0034198""(cellular response to amino acid starvation)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035859""(Seh1-associated complex)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046872""(metal ion binding)|go:""GO:0061700""(GATOR2 complex)|go:""GO:1904262""(negative regulation of TORC1 signaling)|go:""GO:1904263""(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR006575(RWD)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR039456|interpro:IPR049566|interpro:IPR049567|mint:Q6PJI9|rcsb pdb:7UHY|reactome:R-HSA-9639288|refseq:NP_001311100.1|panther:PTHR46170(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR011112(Rho termination factor, N-terminal)|interpro:IPR011113(Rho termination factor, RNA-binding)|interpro:IPR004665(Transcription termination factor Rho)|interpro:IPR027417|go:""GO:0003723""(RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002211989.1|interpro:IPR036269|interpro:IPR041703|refseq:YP_002348745.1|panther:PTHR46425(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7yMOhbv8kjVuL8I+Zs+8fLF933k9606	rogid:d6NkDZjvNCwgkhXxhvckAvDrcJE632	intact-crc:422FC7D3DE173B77|rigid:zn+70A5IEfcpXCIlqIlCcGu2t98	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZHG7	uniprotkb:Q9H1Z4	intact:EBI-2843887|uniprotkb:Q0WIB0	intact:EBI-2850249|uniprotkb:Q9NWW4|uniprotkb:Q9BUL7|uniprotkb:Q06DX1|uniprotkb:Q06DW8|uniprotkb:Q06DX0|ensembl:ENSP00000218056.5|ensembl:ENSP00000365919.5|intact:EBI-28984741	psi-mi:metk_yerpe(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:MAT(gene name synonym)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:YPO0931(locus name)|uniprotkb:y3314(locus name)|uniprotkb:YP_3512(locus name)	psi-mi:wdr13_human(display_long)|uniprotkb:WDR13(gene name)|psi-mi:WDR13(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850256|imex:IM-13779-5440	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004478""(methionine adenosyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006556""(S-adenosylmethionine biosynthetic process)|go:""GO:0006730""(one-carbon metabolic process)|refseq:WP_002209971.1|refseq:YP_002345978.1|panther:PTHR11964(orthology-group)"	"refseq:XP_011542249.1|refseq:NP_060353.2|refseq:NP_001159898.1|refseq:NP_001334146.1|refseq:NP_001334148.1|ensembl:ENSG00000101940.18(gene)|ensembl:ENST00000218056.9(transcript)|ensembl:ENST00000376729.10(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0034451""(centriolar satellite)|go:""GO:1904691""(negative regulation of type B pancreatic cell proliferation)|go:""GO:1990841""(promoter-specific chromatin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR051350|mint:Q9H1Z4|panther:PTHR22838(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1htJOEwkQpME5HLtvSLlZmF2H0s632	rogid:FoPaVLp50zwOVJIDzQFIt55nsUI9606	intact-crc:D5F914348156DDCA|rigid:0JKGybt8NbIJcK5vBP4wsZEZYik	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96DI7	uniprotkb:Q8CLD1	intact:EBI-538492|uniprotkb:O75938|uniprotkb:O95320|uniprotkb:B4DQJ1|ensembl:ENSP00000263694.4	intact:EBI-2850229	psi-mi:snr40_human(display_long)|uniprotkb:Prp8-binding protein(gene name synonym)|uniprotkb:U5 snRNP-specific 40 kDa protein(gene name synonym)|uniprotkb:38 kDa-splicing factor(gene name synonym)|uniprotkb:SNRNP40(gene name)|psi-mi:SNRNP40(display_short)|uniprotkb:PRP8BP(gene name synonym)|uniprotkb:SFP38(gene name synonym)|uniprotkb:WDR57(gene name synonym)|uniprotkb:WD repeat-containing protein 57(gene name synonym)	psi-mi:q8cld1_yerpe(display_long)|uniprotkb:y1564(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850232|imex:IM-13779-5437	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004805.2|ensembl:ENSG00000060688.13(gene)|ensembl:ENST00000263694.9(transcript)|go:""GO:0000375""(RNA splicing, via transesterification reactions)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005682""(U5 snRNP)|go:""GO:0005732""(""sno(s)RNA-containing ribonucleoprotein complex"")|go:""GO:0005829""(cytosol)|go:""GO:0006396""(RNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0016607""(nuclear speck)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR052234|mint:Q96DI7|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8Q7Q|rcsb pdb:8Q7V|rcsb pdb:8Q7W|rcsb pdb:8Q7X|rcsb pdb:8QO9|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RC0|rcsb pdb:8RM5|rcsb pdb:8RO2|rcsb pdb:8Y6O|rcsb pdb:9FMD|reactome:R-HSA-72163|reactome:R-HSA-72165|panther:PTHR44006(orthology-group)"	"interpro:IPR048389|interpro:IPR018702|go:""GO:0016020""(membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AfLoHYSy0MlW+OqHyEULLcpwQhQ9606	rogid:kAuAUTBNF97Gsz+tSnt2gelvuPs632	intact-crc:4FB8B8418AC717C4|rigid:c9UoLYMKHGCSk8wrki21IZGYRHo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W240	uniprotkb:Q9Y2W2	intact:EBI-2850287|uniprotkb:Q74VW1|uniprotkb:Q7CJX7|uniprotkb:Q0WD93	intact:EBI-714455|uniprotkb:Q96AY8|ensembl:ENSP00000261167.2	psi-mi:a0a0h2w240_yerpe(display_long)|uniprotkb:YPO2804(locus name)	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850284|imex:IM-13779-5444	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002209759.1|refseq:YP_002347745.1	"refseq:NP_057396.1|ensembl:ENSG00000084463.8(gene)|ensembl:ENST00000261167.7(transcript)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006364""(rRNA processing)|go:""GO:0006397""(mRNA processing)|go:""GO:0008380""(RNA splicing)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0050699""(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|rcsb pdb:7ABG|reactome:R-HSA-72163|panther:PTHR13361(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JhYA2WkP/pLAsCxyNh5bCfVn+IA632	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	intact-crc:F461A8AA82BD1F09|rigid:EPTeAsQ63Sj9Ga5qodnKul21EV8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UMN6	uniprotkb:A0A2S9PLQ4	intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837.2	intact:EBI-2850273|uniprotkb:Q74RV3|uniprotkb:Q0WJ73|uniprotkb:Q7CGD4|uniprotkb:A0A0H2W7Y4	psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym)	psi-mi:a0a2s9plq4_yerpe(display_long)|uniprotkb:YPO0593(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850277|imex:IM-13779-5441	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000272333.8(gene)|ensembl:ENST00000420124.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0032259""(methylation)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042800""(histone H3K4 methyltransferase activity)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0045322""(unmethylated CpG binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140945""(histone H3K4 monomethyltransferase activity)|go:""GO:0140999""(histone H3K4 trimethyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|interpro:IPR046341|interpro:IPR047219|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-9772755|refseq:NP_055542.1|dip:DIP-34598N|efo:""Orphanet:528084""|efo:""Orphanet:589618""|panther:PTHR45838(orthology-group)"	refseq:WP_002210398.1|interpro:IPR036457|refseq:YP_002345665.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/24	rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606	rogid:4kqACx6zUNpUs/XEEncBiVDWpxE632	intact-crc:D4309DD380797391|rigid:glovLuJYOocCCJDBGeJz+KUKB50	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BTA9	uniprotkb:A0A2U2GX04	intact:EBI-749118|intact:EBI-947208|uniprotkb:C9JBT9|uniprotkb:Q5JU75|uniprotkb:Q5JU77|uniprotkb:Q53EN9|uniprotkb:Q5VXK0|uniprotkb:Q5VXK2|uniprotkb:Q8TCK1|uniprotkb:Q96DP3|uniprotkb:Q96FW6|uniprotkb:Q96JI3|uniprotkb:A8K2A9|intact:EBI-1105304|uniprotkb:D3DRW5|uniprotkb:D3DRW6|uniprotkb:D3DRW7|ensembl:ENSP00000346986.4	intact:EBI-2850302|uniprotkb:Q74RC2|uniprotkb:A0A0H2W7A4|uniprotkb:A0A5P8YAU6|uniprotkb:Q7CL05|uniprotkb:A0A384KDB1	psi-mi:wac_human(display_long)|uniprotkb:WAC(gene name)|psi-mi:WAC(display_short)|uniprotkb:KIAA1844(gene name synonym)	psi-mi:a0a2u2gx04_yerpe(display_long)|uniprotkb:YPO3906(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850307|imex:IM-13779-5443	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000095787.26(gene)|ensembl:ENST00000354911.9(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006974""(DNA damage response)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016607""(nuclear speck)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:1904263""(positive regulation of TORC1 signaling)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|interpro:IPR038867|mint:Q9BTA9|reactome:R-HSA-8866654|refseq:NP_057712.2|refseq:NP_567822.1|refseq:NP_567823.1|refseq:XP_011517793.1|efo:""Orphanet:284169""|efo:""Orphanet:466950""|panther:PTHR15911(orthology-group)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR053777|refseq:WP_002212022.1|refseq:YP_002348781.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TuCxRb98Y5EGRbK1RRNMi/VnXV89606	rogid:QOvYHsMlk2znb0YhwxWfUhF8SCQ632	intact-crc:0B8858A2DB23AE5D|rigid:tASOhaQycyfhFdPBO1PUkkx1yBo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1P8	uniprotkb:Q9BTA9	intact:EBI-2841883	intact:EBI-749118|intact:EBI-947208|uniprotkb:C9JBT9|uniprotkb:Q5JU75|uniprotkb:Q5JU77|uniprotkb:Q53EN9|uniprotkb:Q5VXK0|uniprotkb:Q5VXK2|uniprotkb:Q8TCK1|uniprotkb:Q96DP3|uniprotkb:Q96FW6|uniprotkb:Q96JI3|uniprotkb:A8K2A9|intact:EBI-1105304|uniprotkb:D3DRW5|uniprotkb:D3DRW6|uniprotkb:D3DRW7|ensembl:ENSP00000346986.4	psi-mi:q8d1p8_yerpe(display_long)|uniprotkb:tcaA1(gene name)|psi-mi:tcaA1(display_short)|uniprotkb:y0183(locus name)	psi-mi:wac_human(display_long)|uniprotkb:WAC(gene name)|psi-mi:WAC(display_short)|uniprotkb:KIAA1844(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850295|imex:IM-13779-5442	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR018003	"ensembl:ENSG00000095787.26(gene)|ensembl:ENST00000354911.9(transcript)|go:""GO:0000993""(RNA polymerase II complex binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0006338""(chromatin remodeling)|go:""GO:0006974""(DNA damage response)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0016607""(nuclear speck)|go:""GO:0031571""(mitotic G1 DNA damage checkpoint signaling)|go:""GO:0032435""(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:1904263""(positive regulation of TORC1 signaling)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|interpro:IPR038867|mint:Q9BTA9|reactome:R-HSA-8866654|refseq:NP_057712.2|refseq:NP_567822.1|refseq:NP_567823.1|refseq:XP_011517793.1|efo:""Orphanet:284169""|efo:""Orphanet:466950""|panther:PTHR15911(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:LfA2Lz71pTe9HDOA0UOS0/RgEsY632	rogid:TuCxRb98Y5EGRbK1RRNMi/VnXV89606	intact-crc:C1136747906FC413|rigid:w14GJqxcgAlIQJV2nEJp/JK5K+c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VA10	uniprotkb:Q9UMN6	intact:EBI-2850266	intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837.2	psi-mi:a0a6b3va10_yerpe(display_long)|uniprotkb:y0277(locus name)	psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850263|imex:IM-13779-5445	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010263(Protein of unknown function DUF876, bacterial)|uniprotkb:A0A6B3T7M5(uniprot-removed-ac)|refseq:WP_002223800.1	"ensembl:ENSG00000272333.8(gene)|ensembl:ENST00000420124.4(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0032259""(methylation)|go:""GO:0035097""(histone methyltransferase complex)|go:""GO:0042800""(histone H3K4 methyltransferase activity)|go:""GO:0044665""(MLL1/2 complex)|go:""GO:0045322""(unmethylated CpG binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0140945""(histone H3K4 monomethyltransferase activity)|go:""GO:0140999""(histone H3K4 trimethyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|interpro:IPR046341|interpro:IPR047219|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-9772755|refseq:NP_055542.1|dip:DIP-34598N|efo:""Orphanet:528084""|efo:""Orphanet:589618""|panther:PTHR45838(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/24	rogid:U7mIOQN35z3zKDypRVXUt0yByck632	rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606	intact-crc:D909713A80969349|rigid:u5chGhmnQNDYtVxX83ppvbVTko4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A1U8QHQ0	uniprotkb:P04275	intact:EBI-2840758|uniprotkb:Q65AJ9|uniprotkb:Q9ZGY2|uniprotkb:Q74YJ4	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:a0a1u8qhq0_yerpe(display_long)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850321|imex:IM-13779-5449	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_093949.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:rXeU11b3IU9s8vPezxuQvde9xyE632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:99B04033FDD0AFBC|rigid:a7oVHNvN/Hj0vD7GpfElE/7CM+Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0V0	uniprotkb:P04275	intact:EBI-2849272	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:q8d0v0_yerpe(display_long)|uniprotkb:fadL(gene name)|psi-mi:fadL(display_short)|uniprotkb:Outer membrane FadL protein(gene name synonym)|uniprotkb:Outer membrane flp protein(gene name synonym)|uniprotkb:y1577(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850339|imex:IM-13779-5448	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005017(Membrane protein involved in aromatic hydrocarbon degradation)|go:""GO:0006869""(lipid transport)|go:""GO:0009279""(cell outer membrane)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:t3ttYDBykbAjdOq/JpJE2QGeyvk632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:5E9D3371D2A40C58|rigid:tc+nsuo93guHat4EIXEat2SwyLU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1M9	uniprotkb:P04275	intact:EBI-2850328	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:q8d1m9_yerpe(display_long)|uniprotkb:y0255(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850332|imex:IM-13779-5447	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008727(PAAR)|interpro:IPR001826(RHS protein)|interpro:IPR022385|interpro:IPR006530(YD repeat)|interpro:IPR031325|go:""GO:0016020""(membrane)|interpro:IPR050708|interpro:IPR045351"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Cab3pCzvfMqKzL/7edtHOtYi1fY632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:FC4B4271D018C5BB|rigid:oyfkYOpiLLwxScqsfr/OHVt2cqE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04275	uniprotkb:Q8D0R5	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	intact:EBI-2850346|uniprotkb:Q74T91	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:q8d0r5_yerpe(display_long)|uniprotkb:cpsG(gene name)|psi-mi:cpsG(display_short)|uniprotkb:y1710(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850351|imex:IM-13779-5450	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016868""(intramolecular phosphotransferase activity)|interpro:IPR036900"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:z2kz1BX3Sd7E73WGqRSF6X0AGrM632	intact-crc:2E593371D38A7D39|rigid:bc7mxE3GSec5vRvZAmeaBeOeEDI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04275	uniprotkb:P58492	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	intact:EBI-2843087|uniprotkb:Q0WCS4	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:zipa_yerpe(display_long)|uniprotkb:zipA(gene name)|psi-mi:zipA(display_short)|uniprotkb:YPO2990(locus name)|uniprotkb:y1491(locus name)|uniprotkb:YP_2615(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850314|imex:IM-13779-5446	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"interpro:IPR011919(Cell division protein ZipA)|interpro:IPR007449(ZipA, C-terminal FtsZ-binding region)|go:""GO:0000917""(division septum assembly)|go:""GO:0005886""(plasma membrane)|go:""GO:0032153""(cell division site)|go:""GO:0043093""(FtsZ-dependent cytokinesis)|interpro:IPR036765|refseq:WP_002227089.1|refseq:YP_002347914.1|panther:PTHR38685(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:BeJdUMpcAUuTee/AiHsPfnL/+wg632	intact-crc:84E18BFE3278BD11|rigid:2ioVkQhtIfBCEWDwoGd7XQDQ+WM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H0M8	uniprotkb:P04275	intact:EBI-2849144|uniprotkb:Q74XP9|uniprotkb:A0A3N4B5K6|uniprotkb:A0A0H2W284|uniprotkb:Q7CKB5|uniprotkb:A0A384KE37	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:a0a2u2h0m8_yerpe(display_long)|uniprotkb:fumA(gene name)|psi-mi:fumA(display_short)|uniprotkb:fumB(gene name synonym)|uniprotkb:YPO3335(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850391|imex:IM-13779-5453	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR020557|refseq:WP_002209418.1|interpro:IPR004646(Fe-S type hydro-lyases tartrate/fumarate alpha region)|interpro:IPR004647(Fe-S type hydro-lyases tartrate/fumarate beta region)|interpro:IPR011167(Iron-dependent fumarate hydratase)|go:""GO:0004333""(fumarate hydratase activity)|go:""GO:0006091""(generation of precursor metabolites and energy)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR036660|refseq:YP_002348231.1|interpro:IPR051208"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:+RE2hmq93gVFPvEwC+LKqnvbWt8632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:BADC0933DDBFE83E|rigid:arU40f9WD3uzwkBj320J46F7upY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D030	uniprotkb:P04275	intact:EBI-2850372|uniprotkb:Q74VM7	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:q8d030_yerpe(display_long)|uniprotkb:sdaC(gene name)|psi-mi:sdaC(display_short)|uniprotkb:sdaC2(gene name synonym)|uniprotkb:YP_1271(locus name)|uniprotkb:y2862(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850377|imex:IM-13779-5454	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004694(Serine transporter)|interpro:IPR018227|go:""GO:0005886""(plasma membrane)|go:""GO:0015171""(amino acid transmembrane transporter activity)|go:""GO:0015293""(symporter activity)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Wr4jF7QNki1mRAcVdThEoCppiz0632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:EA683371D2B21C84|rigid:4n5gk6XFr9rJ2adEecuoyW2MhPM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D090	uniprotkb:P04275	intact:EBI-2841134|uniprotkb:Q74V49	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:q8d090_yerpe(display_long)|uniprotkb:aroP(gene name)|psi-mi:aroP(display_short)|uniprotkb:aroP2(gene name synonym)|uniprotkb:YP_1484(locus name)|uniprotkb:y2564(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850358|imex:IM-13779-5455	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004840(Amino acid permease, conserved site)|go:""GO:0006865""(amino acid transport)|go:""GO:0016020""(membrane)|go:""GO:0055085""(transmembrane transport)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:LWeGZBjVR+c7xlmU55b1frR4kCQ632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:CB023371D2B04281|rigid:z4fmZtlQSyNKFn5+VgAFj8Oz5LQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04275	uniprotkb:Q8D065	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	intact:EBI-2847402	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:q8d065_yerpe(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:y2699(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850365|imex:IM-13779-5451	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"refseq:WP_002223447.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR017729(Type VI secretion system ATPase, ClpV1)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR036628|interpro:IPR041546|interpro:IPR004176(Clp, N-terminal)|interpro:IPR050130"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:Nh2TczmhYbmKmz+LT5cThSxQiU8632	intact-crc:D7DD3371D39C311A|rigid:E4f/q705TaSwGA9aHgzCD5X6Wa4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04275	uniprotkb:A0A2S9PBP0	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	intact:EBI-2843228|uniprotkb:Q74PK6|uniprotkb:Q7CL58|uniprotkb:A0A3N4BAA7|uniprotkb:A0A0H2WA10	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:a0a2s9pbp0_yerpe(display_long)|uniprotkb:YPO3648(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850384|imex:IM-13779-5452	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"interpro:IPR015815(3-hydroxyacid dehydrogenase/reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR002204(3-hydroxyisobutyrate dehydrogenase-related, conserved site)|interpro:IPR029154|refseq:WP_002210056.1|go:""GO:0016054""(organic acid catabolic process)|go:""GO:0016616""(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:""GO:0050661""(NADP binding)|go:""GO:0051287""(NAD binding)|interpro:IPR036291|refseq:YP_002348533.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:aYeaLvaUeXHyF5tQMvpaMGoy1ME632	intact-crc:040BD9DEEF63BFAB|rigid:IpsnPH7KTjB0OkPMF7RupYoHuHk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GVZ6	uniprotkb:P04275	intact:EBI-2842971|uniprotkb:Q74W16|uniprotkb:A0A0H2W2X1|uniprotkb:Q7CJU6|uniprotkb:A0A3N4AZS9|uniprotkb:A0A384L7G7	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:a0a2u2gvz6_yerpe(display_long)|uniprotkb:ubiF(gene name)|psi-mi:ubiF(display_short)|uniprotkb:YPO2621(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850424|imex:IM-13779-5458	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR010971(Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6)|go:""GO:0004497""(monooxygenase activity)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0016705""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:""GO:0071949""(FAD binding)|refseq:WP_002210347.1|interpro:IPR036188|refseq:YP_002347577.1|interpro:IPR051205"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:zKOVHd4RmzcakJDi4rlK0Xy9yNc632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:7A70F7C0DC82477D|rigid:kumXoo7WbJiZCJtfYkX6dZafuO8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04275	uniprotkb:A0A380PFU9	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	intact:EBI-2840119|uniprotkb:Q74WY9|uniprotkb:Q0WC33|uniprotkb:Q7CK71	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:a0a380pfu9_yerpe(display_long)|uniprotkb:YPO3255(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850405|imex:IM-13779-5459	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"interpro:IPR010065(Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine)|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0005886""(plasma membrane)|go:""GO:0006865""(amino acid transport)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0043190""(""ATP-binding cassette (ABC) transporter complex"")|refseq:WP_002208733.1|refseq:YP_002348155.1|interpro:IPR035906|interpro:IPR043429|panther:PTHR30614(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:DyP+34ypLTaWK1mXJ81YYpVtIbk632	intact-crc:2424BB75AE6B2A7F|rigid:rAjUNslg6bRVie98LyrhIEapZ5s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W206	uniprotkb:P04275	intact:EBI-2850412|uniprotkb:Q74WX4|uniprotkb:Q0WC54|uniprotkb:A0A3N4AY03|uniprotkb:Q7CK63|uniprotkb:A0A384LHY7	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:a0a0h2w206_yerpe(display_long)|uniprotkb:YPO3232(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850417|imex:IM-13779-5457	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017946|refseq:WP_002208709.1|interpro:IPR030395|go:""GO:0006629""(lipid metabolic process)|go:""GO:0008081""(phosphoric diester hydrolase activity)|refseq:YP_002348134.1"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:w9E1M7ll1/8M9c7G+MFNmcATVX4632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:7FD0C96C4B1BB91E|rigid:efSroz4Vu5tO8soU62r0NK4psEE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PM91	uniprotkb:P04275	intact:EBI-2845565|uniprotkb:Q74XN3|uniprotkb:Q7CKA1|uniprotkb:A0A0H2W0J0|uniprotkb:Q0WBX7	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:a0a2s9pm91_yerpe(display_long)|uniprotkb:rbsC(gene name)|psi-mi:rbsC(display_short)|uniprotkb:YPO3315(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850398|imex:IM-13779-5456	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001851(Bacterial inner-membrane translocator)|refseq:WP_002209437.1|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|refseq:YP_002348211.1"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:QdtHo9H/Vuz7QOXdAkSbm2MTatU632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:B90732FA7F470B64|rigid:/Z5KfqLd0jWUA5quWFHcISpMGb0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WH72	uniprotkb:P04275	intact:EBI-2850434|uniprotkb:Q74VP2|uniprotkb:A0A2S9PE74|uniprotkb:Q7CHH1|uniprotkb:A0A0H2W437	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:q0wh72_yerpe(display_long)|uniprotkb:YPO1343(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850431|imex:IM-13779-5460	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR002491(Periplasmic binding protein)|refseq:YP_002346366.1|interpro:IPR050902	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:mNlEz7MBUwvI3HEqPO5jS8aG5zo632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:7A56DD195A0A8199|rigid:+5nIorj81sb92kpO+U85Gn84Q+A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H1V6	uniprotkb:P04275	intact:EBI-2850465|uniprotkb:Q74PV9|uniprotkb:Q0WJQ5|uniprotkb:Q7CG45|uniprotkb:A0A384KII1	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:a0a2u2h1v6_yerpe(display_long)|uniprotkb:YPO0406(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850469|imex:IM-13779-5464	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR019637|refseq:WP_002209184.1|refseq:YP_002345483.1	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:5RKYACMR3t6yS5I31AaUbnCyjSU632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:34A8FD82C3A0EAF1|rigid:9y5bJudEbLJqqZiCvcqlpW24um4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04275	uniprotkb:A0A2U2H437	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	intact:EBI-2850456|uniprotkb:Q74WF0|uniprotkb:Q0WHJ0|uniprotkb:A0A3N4B7H3|uniprotkb:Q7CH95|uniprotkb:A0A384KJJ3	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:a0a2u2h437_yerpe(display_long)|uniprotkb:nrdA(gene name synonym)|uniprotkb:dnaF(gene name)|psi-mi:dnaF(display_short)|uniprotkb:YPO1214(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850453|imex:IM-13779-5461	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"interpro:IPR005144(ATP-cone)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|refseq:WP_002210818.1|interpro:IPR039718|go:""GO:0004748""(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:""GO:0005524""(ATP binding)|go:""GO:0009263""(deoxyribonucleotide biosynthetic process)|refseq:YP_002346248.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:R11RUqHq7xUDr6lALnevk0/1yxY632	intact-crc:05C55F73C5276BAB|rigid:w6oJmzHqTnRSCms0mG4onUREpmQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04275	uniprotkb:A0A7Y8RC16	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	intact:EBI-2843188|uniprotkb:Q74PV7|uniprotkb:A0A0H2W7X5|uniprotkb:Q7CG44|uniprotkb:Q0WJQ7|uniprotkb:A0A384KPQ0	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:a0a7y8rc16_yerpe(display_long)|uniprotkb:YPO0404(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850476|imex:IM-13779-5462	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR006327(Phosphotransferase system, fructose IIC component)|interpro:IPR013014(Phosphotransferase system, EIIC component, type 2)|go:""GO:0005351""(""carbohydrate:proton symporter activity"")|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|refseq:YP_002345481.1|interpro:IPR050864"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:SLkzxzvdatLCfveYdH0UaKifvHU632	intact-crc:DA6F54A3B5DC2E8F|rigid:wKZ1zDbFdePUEzeb1ryXORcRtMA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H486	uniprotkb:P04275	intact:EBI-2850446|uniprotkb:Q0WHI0|uniprotkb:Q7CHA3|uniprotkb:A0A384KIF1	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:a0a2u2h486_yerpe(display_long)|uniprotkb:YPO1228(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850443|imex:IM-13779-5465	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001279(Beta-lactamase-like)|interpro:IPR024884|refseq:WP_002208869.1|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0070290""(N-acylphosphatidylethanolamine-specific phospholipase D activity)|interpro:IPR036866|refseq:YP_002346258.1|panther:PTHR15032(orthology-group)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:qsEZ6RhMfME88TcBAE5zlG25Fn8632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:7289BA2B2892330A|rigid:akD0XvfLInZvF38VUBDj8l09RV8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CFY4	uniprotkb:P04275	intact:EBI-2839980|uniprotkb:Q0WA73	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	psi-mi:q7cfy4_yerpe(display_long)|uniprotkb:YPO3944(locus name)	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850483|imex:IM-13779-5463	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003344(Bacterial Ig-like, group 1)|interpro:IPR024519|interpro:IPR003535(Intimin bacterial adhesion mediator protein)|interpro:IPR008964(Invasin/intimin cell-adhesion)|interpro:IPR018392|refseq:YP_002348815.1|interpro:IPR016186(C-type lectin-like)|interpro:IPR048658|go:""GO:0007155""(cell adhesion)|go:""GO:0009279""(cell outer membrane)|interpro:IPR038177|refseq:WP_002228169.1|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036779|interpro:IPR051715|panther:PTHR39576(orthology-group)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:HyjrywO1mfKosC2W72qtvq9hL6w632	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	intact-crc:FFA4E3DF0CD49381|rigid:cYC0JLAc3RLNJIKfSNSaI8N0ndg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5VIR6	uniprotkb:Q8D048	intact:EBI-2850511|uniprotkb:Q9BY02|uniprotkb:A8K2S8|uniprotkb:Q9BRR2|uniprotkb:Q9NV25|uniprotkb:Q8WYW3|uniprotkb:B3FH42|ensembl:ENSP00000401435.2|ensembl:ENSP00000492761.1|ensembl:ENSP00000505997.1	intact:EBI-2850523|uniprotkb:Q74VT8	psi-mi:vps53_human(display_long)|uniprotkb:PP13624(orf name)|uniprotkb:VPS53(gene name)|psi-mi:VPS53(display_short)	psi-mi:q8d048_yerpe(display_long)|uniprotkb:smtA(gene name)|psi-mi:smtA(display_short)|uniprotkb:cmo5U methyltransferase(gene name synonym)|uniprotkb:cmoM(gene name synonym)|uniprotkb:y2768(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850520|imex:IM-13779-5468	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000141252.21(gene)|ensembl:ENSG00000283883.2(gene)|ensembl:ENST00000437048.7(transcript)|ensembl:ENST00000639801.2(transcript)|ensembl:ENST00000680465.1(transcript)|go:""GO:0000938""(GARP complex)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006622""(protein targeting to lysosome)|go:""GO:0007041""(lysosomal transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032588""(trans-Golgi network membrane)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0055037""(recycling endosome)|go:""GO:0090119""(vesicle-mediated cholesterol transport)|go:""GO:1990745""(EARP complex)|interpro:IPR007234(Vps53-like, N-terminal)|interpro:IPR031745|interpro:IPR038260|interpro:IPR039766|mint:Q5VIR6|reactome:R-HSA-6811440|refseq:NP_001121631.1|refseq:NP_060759.2|dip:DIP-59352N|efo:""Orphanet:247198""|panther:PTHR12820(orthology-group)"	"interpro:IPR029063|interpro:IPR025714|interpro:IPR033664|go:""GO:0006400""(tRNA modification)|go:""GO:0032259""(methylation)|go:""GO:0097697""(""tRNA (5-carboxymethoxyuridine(34)-5-O)-methyltransferase activity"")"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:gnrMqPquSOGNPQYESYuA7ztMI0Y9606	rogid:C2p3G9zkPefTAF2KGEnmAqFEusE632	intact-crc:B1DDA1A444B4E411|rigid:xKnEplb6CTiiF7eHdbWX+H0a2XE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P04275	uniprotkb:Q7ARD3	intact:EBI-981819|uniprotkb:Q8TCE8|uniprotkb:Q99806|ensembl:ENSP00000261405.5	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:vwf_human(display_long)|uniprotkb:VWF(gene name)|psi-mi:VWF(display_short)|uniprotkb:F8VWF(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850490|imex:IM-13779-5466	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000110799.14(gene)|ensembl:ENST00000261405.10(transcript)|go:""GO:0002020""(protease binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005518""(collagen binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0007155""(cell adhesion)|go:""GO:0007596""(blood coagulation)|go:""GO:0007599""(hemostasis)|go:""GO:0009611""(response to wounding)|go:""GO:0019865""(immunoglobulin binding)|go:""GO:0030168""(platelet activation)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031091""(platelet alpha granule)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031589""(cell-substrate adhesion)|go:""GO:0033093""(Weibel-Palade body)|go:""GO:0042802""(identical protein binding)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR032361|interpro:IPR036084|interpro:IPR036465|interpro:IPR037578|interpro:IPR050780|mint:P04275|rcsb pdb:1AO3|rcsb pdb:1ATZ|rcsb pdb:1AUQ|rcsb pdb:1FE8|rcsb pdb:1FNS|rcsb pdb:1IJB|dip:DIP-29667N|rcsb pdb:1IJK|rcsb pdb:1M10|rcsb pdb:1OAK|rcsb pdb:1SQ0|rcsb pdb:1U0N|rcsb pdb:1UEX|rcsb pdb:2ADF|rcsb pdb:2MHP|rcsb pdb:2MHQ|rcsb pdb:3GXB|rcsb pdb:3HXO|rcsb pdb:3HXQ|rcsb pdb:3PPV|rcsb pdb:3PPW|rcsb pdb:3PPX|rcsb pdb:3PPY|rcsb pdb:3ZQK|rcsb pdb:4C29|rcsb pdb:4C2A|rcsb pdb:4C2B|rcsb pdb:4DMU|rcsb pdb:4NT5|rcsb pdb:5BV8|rcsb pdb:6FWN|rcsb pdb:6N29|rcsb pdb:7EOW|rcsb pdb:7F49|rcsb pdb:7KWO|rcsb pdb:7P4N|rcsb pdb:7PMV|rcsb pdb:7PNF|rcsb pdb:7ZWH|rcsb pdb:8D3C|rcsb pdb:8D3D|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-430116|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9845619|reactome:R-HSA-9845620|reactome:R-HSA-9845621|reactome:R-HSA-9845622|reactome:R-HSA-9846298|refseq:NP_000543.2|efo:""Orphanet:166078""|efo:""Orphanet:166084""|efo:""Orphanet:166087""|efo:""Orphanet:166090""|efo:""Orphanet:166093""|efo:""Orphanet:166096""|panther:PTHR11339(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:yeGxC2SyyvUZ3hNciww1o8TmY5Q9606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:CB8A8D3D0D446C5D|rigid:2TH2hJxyDbf6qgVK/fE0OKOqhVI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96DN2	uniprotkb:Q8D1N2	intact:EBI-2850497|uniprotkb:Q86WK8|uniprotkb:A5PKV0|uniprotkb:Q7Z7L6|ensembl:ENSP00000334186.5	intact:EBI-2841512|uniprotkb:Q74PI8	psi-mi:vwce_human(display_long)|uniprotkb:VWCE(gene name)|psi-mi:VWCE(display_short)|uniprotkb:URG11(gene name synonym)|uniprotkb:HBV X protein up-regulated gene 11 protein(gene name synonym)|uniprotkb:HBxAg up-regulated gene 11 protein(gene name synonym)	psi-mi:q8d1n2_yerpe(display_long)|uniprotkb:nhaP(gene name)|psi-mi:nhaP(display_short)|uniprotkb:YP_3917(locus name)|uniprotkb:y0238(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850504|imex:IM-13779-5467	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_689931.2|ensembl:ENSG00000167992.14(gene)|ensembl:ENST00000335613.10(transcript)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0098586""(cellular response to virus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR052080|mint:Q96DN2|panther:PTHR47333(orthology-group)"	"interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR004705(Bacterial Na+/H+ antiporter)|go:""GO:0005886""(plasma membrane)|go:""GO:0015385""(""sodium:proton antiporter activity"")"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iBs6xSgpnuM95cf8NssaHvB9bSI9606	rogid:FMx9zeBSSrmC2GfOs9V4IVDkTRs632	intact-crc:92FCAFAF08E7B83A|rigid:hOl88aE1lMEvxvDcb+wZQvbP/sA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96JC1	uniprotkb:Q0WKQ4	intact:EBI-1050197|uniprotkb:O94869|uniprotkb:Q7Z3V3|uniprotkb:Q96B93|uniprotkb:Q96RM0|uniprotkb:Q71SQ6|ensembl:ENSP00000335193.5	intact:EBI-2841918|uniprotkb:Q74YB1|uniprotkb:Q7CLB1|uniprotkb:A0A5P8YL50|uniprotkb:A0A0H2W0T4	psi-mi:vps39_human(display_long)|uniprotkb:KIAA0770(gene name synonym)|uniprotkb:VPS39(gene name)|psi-mi:VPS39(display_short)|uniprotkb:VAM6(gene name synonym)|uniprotkb:TLP(gene name synonym)|uniprotkb:TRAP1-like protein(gene name synonym)	psi-mi:q0wkq4_yerpe(display_long)|uniprotkb:spoT(gene name)|psi-mi:spoT(display_short)|uniprotkb:YPO0038(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850532|imex:IM-13779-5473	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056104.2|refseq:NP_001288067.1|ensembl:ENSG00000166887.16(gene)|ensembl:ENST00000348544.4(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006914""(autophagy)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0030123""(AP-3 adaptor complex)|go:""GO:0030897""(HOPS complex)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032456""(endocytic recycling)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0035542""(regulation of SNARE complex assembly)|go:""GO:0061909""(autophagosome-lysosome fusion)|go:""GO:1902501""(lysosomal HOPS complex)|go:""GO:1902774""(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001180(Citron-like)|interpro:IPR019452|interpro:IPR019453|interpro:IPR032914|mint:Q96JC1|rcsb pdb:6ZE9|reactome:R-HSA-9754560|panther:PTHR12894(orthology-group)"	"interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR007685(RelA/SpoT)|interpro:IPR004811(RelA/SpoT protein)|interpro:IPR004095(TGS)|interpro:IPR012676(TGS-like)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR033655|go:""GO:0015970""(guanosine tetraphosphate biosynthetic process)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002209002.1|interpro:IPR043519|refseq:YP_002345134.1|interpro:IPR045600|interpro:IPR045865"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BeY8ZDCOyTvZqA0WpdWnmz+giYk9606	rogid:DFSylU3fdvQugjKDCGmQic4raK0632	intact-crc:98BBFEF43893AFC9|rigid:A5MwQJ9RLJ1AyFdOBgfG6MBGb0Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96QK1	uniprotkb:Q0WGT7	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138.7	intact:EBI-2850542|uniprotkb:Q74VD6|uniprotkb:Q7CHP0|uniprotkb:A0A0H2W4Q1	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:q0wgt7_yerpe(display_long)|uniprotkb:YPO1485(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850539|imex:IM-13779-5469	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:411602""|dip:DIP-29076N|rcsb pdb:8R0J|rcsb pdb:8RKS|reactome:R-HSA-3238698|ensembl:ENSG00000069329.19(gene)|ensembl:ENST00000299138.12(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007040""(lysosome organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030906""(retromer, cargo-selective complex)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031648""(protein destabilization)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032463""(negative regulation of protein homooligomerization)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0045056""(transcytosis)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050882""(voluntary musculoskeletal movement)|go:""GO:0051246""(regulation of protein metabolic process)|go:""GO:0060161""(positive regulation of dopamine receptor signaling pathway)|go:""GO:0061357""(positive regulation of Wnt protein secretion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090141""(positive regulation of mitochondrial fission)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090326""(positive regulation of locomotion involved in locomotory behavior)|go:""GO:0097422""(tubular endosome)|go:""GO:0098691""(dopaminergic synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099003""(vesicle-mediated transport in synapse)|go:""GO:0099073""(mitochondrion-derived vesicle)|go:""GO:0099074""(mitochondrion to lysosome vesicle-mediated transport)|go:""GO:0099639""(neurotransmitter receptor transport, endosome to plasma membrane)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902823""(negative regulation of late endosome to lysosome transport)|go:""GO:1902950""(regulation of dendritic spine maintenance)|go:""GO:1903181""(positive regulation of dopamine biosynthetic process)|go:""GO:1903828""(negative regulation of protein localization)|go:""GO:1904377""(positive regulation of protein localization to cell periphery)|go:""GO:1905166""(negative regulation of lysosomal protein catabolic process)|go:""GO:1905606""(regulation of presynapse assembly)|go:""GO:2000331""(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q96QK1|rcsb pdb:2R17|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|rcsb pdb:8R02|refseq:NP_060676.2|panther:PTHR11099(orthology-group)"	interpro:IPR010272(Type VI secretion system, VCA0110)|refseq:WP_002211940.1|refseq:YP_002346501.1|panther:PTHR35370(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:EXkMduDQKNCdp876vGF5vna9t389606	rogid:alKNsFV/5ZWYoWO8CrdjCKkqbEU632	intact-crc:8703D945BD0F0D4A|rigid:l2Sl/3tZBkFVM8gfFRrPX5zyR98	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARD3	uniprotkb:Q96QK1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138.7	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850561|imex:IM-13779-5470	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395386.1	"efo:""Orphanet:411602""|dip:DIP-29076N|rcsb pdb:8R0J|rcsb pdb:8RKS|reactome:R-HSA-3238698|ensembl:ENSG00000069329.19(gene)|ensembl:ENST00000299138.12(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007040""(lysosome organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030906""(retromer, cargo-selective complex)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031648""(protein destabilization)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032463""(negative regulation of protein homooligomerization)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0045056""(transcytosis)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050882""(voluntary musculoskeletal movement)|go:""GO:0051246""(regulation of protein metabolic process)|go:""GO:0060161""(positive regulation of dopamine receptor signaling pathway)|go:""GO:0061357""(positive regulation of Wnt protein secretion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090141""(positive regulation of mitochondrial fission)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090326""(positive regulation of locomotion involved in locomotory behavior)|go:""GO:0097422""(tubular endosome)|go:""GO:0098691""(dopaminergic synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099003""(vesicle-mediated transport in synapse)|go:""GO:0099073""(mitochondrion-derived vesicle)|go:""GO:0099074""(mitochondrion to lysosome vesicle-mediated transport)|go:""GO:0099639""(neurotransmitter receptor transport, endosome to plasma membrane)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902823""(negative regulation of late endosome to lysosome transport)|go:""GO:1902950""(regulation of dendritic spine maintenance)|go:""GO:1903181""(positive regulation of dopamine biosynthetic process)|go:""GO:1903828""(negative regulation of protein localization)|go:""GO:1904377""(positive regulation of protein localization to cell periphery)|go:""GO:1905166""(negative regulation of lysosomal protein catabolic process)|go:""GO:1905606""(regulation of presynapse assembly)|go:""GO:2000331""(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q96QK1|rcsb pdb:2R17|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|rcsb pdb:8R02|refseq:NP_060676.2|panther:PTHR11099(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:6CF55661EB793BBC|rigid:14byAbs1JdWfJ9L+cWYULbn4Jpc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H442	uniprotkb:Q96QK1	intact:EBI-2850550|uniprotkb:Q74WH5|uniprotkb:A0A5P8YDV2|uniprotkb:Q0WHG4|uniprotkb:Q7CHB4|uniprotkb:A0A384LD81	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138.7	psi-mi:a0a2u2h442_yerpe(display_long)|uniprotkb:YPO1245(locus name)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850554|imex:IM-13779-5472	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002208853.1|refseq:YP_002346274.1	"efo:""Orphanet:411602""|dip:DIP-29076N|rcsb pdb:8R0J|rcsb pdb:8RKS|reactome:R-HSA-3238698|ensembl:ENSG00000069329.19(gene)|ensembl:ENST00000299138.12(transcript)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0007040""(lysosome organization)|go:""GO:0010008""(endosome membrane)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010821""(regulation of mitochondrion organization)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0030904""(retromer complex)|go:""GO:0030906""(retromer, cargo-selective complex)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0031648""(protein destabilization)|go:""GO:0031748""(D1 dopamine receptor binding)|go:""GO:0032456""(endocytic recycling)|go:""GO:0032463""(negative regulation of protein homooligomerization)|go:""GO:0036010""(protein localization to endosome)|go:""GO:0042147""(retrograde transport, endosome to Golgi)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043653""(mitochondrial fragmentation involved in apoptotic process)|go:""GO:0045056""(transcytosis)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050804""(modulation of chemical synaptic transmission)|go:""GO:0050882""(voluntary musculoskeletal movement)|go:""GO:0051246""(regulation of protein metabolic process)|go:""GO:0060161""(positive regulation of dopamine receptor signaling pathway)|go:""GO:0061357""(positive regulation of Wnt protein secretion)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090128""(regulation of synapse maturation)|go:""GO:0090141""(positive regulation of mitochondrial fission)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0090326""(positive regulation of locomotion involved in locomotory behavior)|go:""GO:0097422""(tubular endosome)|go:""GO:0098691""(dopaminergic synapse)|go:""GO:0098793""(presynapse)|go:""GO:0098887""(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0099003""(vesicle-mediated transport in synapse)|go:""GO:0099073""(mitochondrion-derived vesicle)|go:""GO:0099074""(mitochondrion to lysosome vesicle-mediated transport)|go:""GO:0099639""(neurotransmitter receptor transport, endosome to plasma membrane)|go:""GO:0150052""(regulation of postsynapse assembly)|go:""GO:1902823""(negative regulation of late endosome to lysosome transport)|go:""GO:1902950""(regulation of dendritic spine maintenance)|go:""GO:1903181""(positive regulation of dopamine biosynthetic process)|go:""GO:1903828""(negative regulation of protein localization)|go:""GO:1904377""(positive regulation of protein localization to cell periphery)|go:""GO:1905166""(negative regulation of lysosomal protein catabolic process)|go:""GO:1905606""(regulation of presynapse assembly)|go:""GO:2000331""(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q96QK1|rcsb pdb:2R17|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|rcsb pdb:8R02|refseq:NP_060676.2|panther:PTHR11099(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:BxXs1C2W2KnC7YYSP0bq8vjxXow632	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:8FB368879D292B9A|rigid:oGZ7PNXZ1ptGKWsr1edOncSA/to	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9H269	uniprotkb:A0A2U2H442	intact:EBI-2655929|uniprotkb:Q5JUB1|uniprotkb:Q8WU31|uniprotkb:Q96EE7|uniprotkb:Q96N92|uniprotkb:Q9H1Q4|uniprotkb:Q9H1Q5|ensembl:ENSP00000369810.3	intact:EBI-2850550|uniprotkb:Q74WH5|uniprotkb:A0A5P8YDV2|uniprotkb:Q0WHG4|uniprotkb:Q7CHB4|uniprotkb:A0A384LD81	psi-mi:vps16_human(display_long)|uniprotkb:VPS16(gene name)|psi-mi:VPS16(display_short)	psi-mi:a0a2u2h442_yerpe(display_long)|uniprotkb:YPO1245(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850568|imex:IM-13779-5471	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_072097.2|refseq:NP_536338.1|ensembl:ENSG00000215305.10(gene)|ensembl:ENST00000380445.8(transcript)|go:""GO:0003779""(actin binding)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005768""(endosome)|go:""GO:0005769""(early endosome)|go:""GO:0005770""(late endosome)|go:""GO:0005776""(autophagosome)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0008333""(endosome to lysosome transport)|go:""GO:0010008""(endosome membrane)|go:""GO:0016197""(endosomal transport)|go:""GO:0030136""(clathrin-coated vesicle)|go:""GO:0030424""(axon)|go:""GO:0030897""(HOPS complex)|go:""GO:0031902""(late endosome membrane)|go:""GO:0033263""(CORVET complex)|go:""GO:0034058""(endosomal vesicle fusion)|go:""GO:0035542""(regulation of SNARE complex assembly)|go:""GO:0042144""(vacuole fusion, non-autophagic)|go:""GO:0043025""(neuronal cell body)|go:""GO:0051015""(actin filament binding)|go:""GO:0055037""(recycling endosome)|go:""GO:0097352""(autophagosome maturation)|go:""GO:0098793""(presynapse)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR006926(Vps16, N-terminal)|interpro:IPR016534(Vacuolar protein sorting-associated protein 16)|interpro:IPR038132|mint:Q9H269|rcsb pdb:4BX9|reactome:R-HSA-9754560|panther:PTHR12811(orthology-group)"	refseq:WP_002208853.1|refseq:YP_002346274.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:bm088LmFRv3w0wfvlPMFeottZkw9606	rogid:BxXs1C2W2KnC7YYSP0bq8vjxXow632	intact-crc:33E4DE94E6AC4C42|rigid:qEjteu5l1Ma1QvRmIP+WS9u22+0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLF6	uniprotkb:Q96RL7	intact:EBI-2850623	intact:EBI-1752583|uniprotkb:Q5JSX9|uniprotkb:Q5JSY0|uniprotkb:Q5VYR5|uniprotkb:Q702P4|uniprotkb:Q709D0|uniprotkb:Q86YF8|uniprotkb:Q96S61|uniprotkb:Q9H995|uniprotkb:Q9Y2J1|ensembl:ENSP00000353422.3	psi-mi:q8clf6_yerpe(display_long)|uniprotkb:y1477(locus name)	psi-mi:vp13a_human(display_long)|uniprotkb:VPS13A(gene name)|psi-mi:VPS13A(display_short)|uniprotkb:CHAC(gene name synonym)|uniprotkb:KIAA0986(gene name synonym)|uniprotkb:Chorein(gene name synonym)|uniprotkb:Chorea-acanthocytosis protein(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 13A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850620|imex:IM-13779-5476	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000994(Peptidase M24, catalytic core)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|interpro:IPR029149|interpro:IPR036005|interpro:IPR050659"	"ensembl:ENSG00000197969.14(gene)|ensembl:ENST00000360280.8(transcript)|go:""GO:0005739""(mitochondrion)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0006869""(lipid transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0006914""(autophagy)|go:""GO:0008104""(protein localization)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0009306""(protein secretion)|go:""GO:0010008""(endosome membrane)|go:""GO:0010467""(gene expression)|go:""GO:0014004""(microglia differentiation)|go:""GO:0030218""(erythrocyte differentiation)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0030382""(sperm mitochondrion organization)|go:""GO:0031547""(brain-derived neurotrophic factor receptor signaling pathway)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0035176""(social behavior)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035640""(exploration behavior)|go:""GO:0043005""(neuron projection)|go:""GO:0043025""(neuronal cell body)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0045053""(protein retention in Golgi apparatus)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0060292""(long-term synaptic depression)|go:""GO:0061744""(motor behavior)|go:""GO:0071470""(cellular response to osmotic stress)|go:""GO:0090648""(response to environmental enrichment)|go:""GO:0097225""(sperm midpiece)|go:""GO:0099013""(neuronal dense core vesicle lumen)|go:""GO:0140058""(neuron projection arborization)|go:""GO:0150076""(neuroinflammatory response)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR009543(Vacuolar protein sorting-associated protein)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026847|interpro:IPR026854|interpro:IPR031642|interpro:IPR031645|interpro:IPR031646|interpro:IPR049424|mint:Q96RL7|refseq:NP_001018047.1|refseq:NP_001018048.1|refseq:NP_056001.1|refseq:NP_150648.2|efo:""Orphanet:2388""|panther:PTHR16166(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9ryjaFmbaczIybL5d+xLkpkN6DU632	rogid:GKpJsczlbPL6VtrpaPXX8K5D0xY9606	intact-crc:841E5D92057ADBF1|rigid:ySMqDz12YfdHA9Xp1c/6PlZzFDQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q709C8	uniprotkb:A0A0H2W1D0	intact:EBI-2819265|uniprotkb:Q9P2C6|uniprotkb:Q9NXN8|uniprotkb:Q702P2|uniprotkb:Q6ISR4|uniprotkb:Q709C9|uniprotkb:Q702P3|ensembl:ENSP00000493560.2	intact:EBI-2850611|uniprotkb:Q74XN0|uniprotkb:Q0WBY0|uniprotkb:A0A3N4B5H8|uniprotkb:Q7CKA0|uniprotkb:A0A384KPX7	psi-mi:vp13c_human(display_long)|uniprotkb:VPS13C(gene name)|psi-mi:VPS13C(display_short)|uniprotkb:KIAA1421(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 13C(gene name synonym)	psi-mi:a0a0h2w1d0_yerpe(display_long)|uniprotkb:YPO3312(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850608|imex:IM-13779-5475	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000129003.19(gene)|ensembl:ENST00000644861.2(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005770""(late endosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0006869""(lipid transport)|go:""GO:0006895""(Golgi to endosome transport)|go:""GO:0007005""(mitochondrion organization)|go:""GO:0031902""(late endosome membrane)|go:""GO:0032127""(dense core granule membrane)|go:""GO:0032868""(response to insulin)|go:""GO:0045053""(protein retention in Golgi apparatus)|go:""GO:0070062""(extracellular exosome)|go:""GO:1905090""(negative regulation of type 2 mitophagy)|interpro:IPR009543(Vacuolar protein sorting-associated protein)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026847|interpro:IPR026854|interpro:IPR031642|interpro:IPR031645|interpro:IPR031646|interpro:IPR049424|mint:Q709C8|refseq:NP_001018098.1|refseq:NP_060154.3|refseq:NP_060550.2|refseq:NP_065872.1|efo:""Orphanet:2828""|panther:PTHR16166(orthology-group)"	"interpro:IPR018485|interpro:IPR018484|interpro:IPR000577(Carbohydrate kinase, FGGY)|refseq:WP_002209440.1|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0016301""(kinase activity)|interpro:IPR043129|interpro:IPR042016|refseq:YP_002348208.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zM3OahBkjb8YTi/QR/W0C6MeCxg9606	rogid:TkbiVPrlraU0BBleepm9BhezvWk632	intact-crc:9B7733143574D627|rigid:HDzNjLrMo/PeqH94Y9p2y5CXsrE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D033	uniprotkb:Q8NEZ2	intact:EBI-2850587|uniprotkb:Q74VN9	intact:EBI-2850578|uniprotkb:Q8TBL7|uniprotkb:Q8N3D7|uniprotkb:Q336D5|uniprotkb:Q96DL9|uniprotkb:Q6NW27|ensembl:ENSP00000318629.4	psi-mi:q8d033_yerpe(display_long)|uniprotkb:y2844(locus name)|uniprotkb:artJ(gene name)|psi-mi:artJ(display_short)|uniprotkb:YP_1256(locus name)	psi-mi:vp37a_human(display_long)|uniprotkb:HCRP1(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS37A(gene name synonym)|uniprotkb:Hepatocellular carcinoma-related protein 1(gene name synonym)|uniprotkb:VPS37A(gene name)|psi-mi:VPS37A(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850575|imex:IM-13779-5474	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR005768(Lysine-arginine-ornithine-binding periplasmic protein)|interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR018313|go:""GO:0015276""(ligand-gated monoatomic ion channel activity)|go:""GO:0016020""(membrane)|go:""GO:0030288""(outer membrane-bounded periplasmic space)"	"ensembl:ENSG00000155975.10(gene)|ensembl:ENST00000324849.9(transcript)|go:""GO:0000813""(ESCRT I complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0010008""(endosome membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0031902""(late endosome membrane)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0090148""(membrane fission)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR029012|interpro:IPR037202|mint:Q8NEZ2|rcsb pdb:8E22|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|refseq:NP_001138624.1|refseq:NP_689628.2|refseq:XP_016868510.1|refseq:XP_016868511.1|refseq:XP_016868515.1|efo:""Orphanet:319199""|panther:PTHR13678(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eCu7zvlwGk/T9ZeW7rhuBw8CqPk632	rogid:3wovtCohKzEe90Q2eFq5pIRx2Pc9606	intact-crc:AE76867616F0CAFB|rigid:NvgJXhNf1FrVZI+YlcHD0F8oFOY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P18206	uniprotkb:A0A454Y4S5	intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998.5	intact:EBI-2842434|uniprotkb:Q74PE1|uniprotkb:Q0W9W9|uniprotkb:Q7CFQ1|uniprotkb:A0A384L034	psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)	psi-mi:a0a454y4s5_yerpe(display_long)|uniprotkb:cheM(gene name)|psi-mi:cheM(display_short)|uniprotkb:tar(gene name synonym)|uniprotkb:YPO4062(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850630|imex:IM-13779-5478	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-35570N|ensembl:ENSG00000035403.18(gene)|ensembl:ENST00000211998.10(transcript)|go:""GO:0002009""(morphogenesis of an epithelium)|go:""GO:0002162""(dystroglycan binding)|go:""GO:0003779""(actin binding)|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0005903""(brush border)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005912""(adherens junction)|go:""GO:0005915""(zonula adherens)|go:""GO:0005916""(fascia adherens)|go:""GO:0005925""(focal adhesion)|go:""GO:0007155""(cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0030032""(lamellipodium assembly)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032991""(protein-containing complex)|go:""GO:0034333""(adherens junction assembly)|go:""GO:0034394""(protein localization to cell surface)|go:""GO:0034774""(secretory granule lumen)|go:""GO:0035580""(specific granule lumen)|go:""GO:0035633""(maintenance of blood-brain barrier)|go:""GO:0042383""(sarcolemma)|go:""GO:0042995""(cell projection)|go:""GO:0043034""(costamere)|go:""GO:0043297""(apical junction assembly)|go:""GO:0044291""(cell-cell contact zone)|go:""GO:0045121""(membrane raft)|go:""GO:0045294""(alpha-catenin binding)|go:""GO:0045296""(cadherin binding)|go:""GO:0048675""(axon extension)|go:""GO:0051893""(regulation of focal adhesion assembly)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061826""(podosome ring)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|go:""GO:0090136""(epithelial cell-cell adhesion)|go:""GO:0090636""(outer dense plaque of desmosome)|go:""GO:0090637""(inner dense plaque of desmosome)|go:""GO:1903140""(regulation of establishment of endothelial barrier)|go:""GO:1903561""(extracellular vesicle)|go:""GO:1904702""(regulation of protein localization to adherens junction)|go:""GO:1904813""(ficolin-1-rich granule lumen)|go:""GO:1990357""(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9725370|reactome:R-HSA-9856530|reactome:R-HSA-9860927|refseq:NP_003364.1|refseq:NP_054706.1|efo:""Orphanet:154""|panther:PTHR46180(orthology-group)"	"interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0007165""(signal transduction)|refseq:WP_002209615.1|interpro:IPR032255|refseq:YP_002348919.1|interpro:IPR051310|panther:PTHR43531(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606	rogid:9q/B+fA+5z2go4RyqrxgvIHLpyk632	intact-crc:56038B78EBBE9697|rigid:BYKD5wjTJ2u6QHchYNNOwoasRr8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NEZ2	uniprotkb:Q7CJ96	intact:EBI-2850578|uniprotkb:Q8TBL7|uniprotkb:Q8N3D7|uniprotkb:Q336D5|uniprotkb:Q96DL9|uniprotkb:Q6NW27|ensembl:ENSP00000318629.4	intact:EBI-2850596|uniprotkb:Q74T19	psi-mi:vp37a_human(display_long)|uniprotkb:HCRP1(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS37A(gene name synonym)|uniprotkb:Hepatocellular carcinoma-related protein 1(gene name synonym)|uniprotkb:VPS37A(gene name)|psi-mi:VPS37A(display_short)	psi-mi:pta_yerpe(display_long)|uniprotkb:YPO2567(locus name)|uniprotkb:YP_2378(locus name)|uniprotkb:y1620(locus name)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850601|imex:IM-13779-5477	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000155975.10(gene)|ensembl:ENST00000324849.9(transcript)|go:""GO:0000813""(ESCRT I complex)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005829""(cytosol)|go:""GO:0006612""(protein targeting to membrane)|go:""GO:0006623""(protein targeting to vacuole)|go:""GO:0010008""(endosome membrane)|go:""GO:0016236""(macroautophagy)|go:""GO:0031902""(late endosome membrane)|go:""GO:0036258""(multivesicular body assembly)|go:""GO:0039702""(viral budding via host ESCRT complex)|go:""GO:0043162""(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043328""(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:""GO:0090148""(membrane fission)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR029012|interpro:IPR037202|mint:Q8NEZ2|rcsb pdb:8E22|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|refseq:NP_001138624.1|refseq:NP_689628.2|refseq:XP_016868510.1|refseq:XP_016868511.1|refseq:XP_016868515.1|efo:""Orphanet:319199""|panther:PTHR13678(orthology-group)"	"interpro:IPR016475(Phosphate acetyltransferase, bacteria)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR010766(DRTGG)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|interpro:IPR028979|interpro:IPR027417|go:""GO:0005737""(cytoplasm)|go:""GO:0006085""(acetyl-CoA biosynthetic process)|go:""GO:0008959""(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113|refseq:YP_002347528.1|interpro:IPR050500|panther:PTHR43356(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3wovtCohKzEe90Q2eFq5pIRx2Pc9606	rogid:bqj0y9j0HCwwtdNgPqUC52yFXB4632	intact-crc:83641AD8C8DD86CD|rigid:5QkwCF8qzJRPlRe1HgteVTf7t3Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CJV2	uniprotkb:Q00341	intact:EBI-2850644|uniprotkb:Q74W07	intact:EBI-1049478|uniprotkb:Q9UCY3|uniprotkb:Q53QU2|uniprotkb:B4DTQ2|uniprotkb:E7EM71|ensembl:ENSP00000312042.4|ensembl:ENSP00000375836.1|ensembl:ENSP00000375837.2|intact:EBI-28974616	psi-mi:lpte_yerpe(display_long)|uniprotkb:rlpB(gene name synonym)|uniprotkb:YPO2609(locus name)|uniprotkb:y1183(locus name)|uniprotkb:YP_1104(locus name)|uniprotkb:lptE(gene name)|psi-mi:lptE(display_short)	psi-mi:vigln_human(display_long)|uniprotkb:High density lipoprotein-binding protein(gene name synonym)|uniprotkb:HDLBP(gene name)|psi-mi:HDLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:VGL(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850649|imex:IM-13779-5479	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002210332.1|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015920""(lipopolysaccharide transport)|go:""GO:0043165""(Gram-negative-bacterium-type cell outer membrane assembly)|go:""GO:1990351""(transporter complex)|interpro:IPR007485(Rare lipoprotein B)|rcsb pdb:5IXM|dip:DIP-62067N|refseq:YP_002347565.1|panther:PTHR38098(orthology-group)"	"refseq:NP_005327.1|refseq:NP_976221.1|refseq:NP_001230829.1|refseq:XP_016859429.1|ensembl:ENSG00000115677.18(gene)|ensembl:ENST00000310931.10(transcript)|ensembl:ENST00000391975.5(transcript)|ensembl:ENST00000391976.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008289""(lipid binding)|go:""GO:0034364""(high-density lipoprotein particle)|go:""GO:0045296""(cadherin binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q00341|rcsb pdb:1VIG|rcsb pdb:1VIH|rcsb pdb:2CTE|rcsb pdb:2CTF|rcsb pdb:2CTJ|rcsb pdb:2CTK|rcsb pdb:2CTL|rcsb pdb:2CTM|reactome:R-HSA-8964011|refseq:NP_001307894.1|refseq:NP_001307895.1|refseq:XP_005247059.2|refseq:XP_006712538.1|refseq:XP_011509360.1|refseq:XP_011509362.1|refseq:XP_005247060.2|panther:PTHR10627(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ZA0uZFa7tyLivzBqOzYMpBAHOkc632	rogid:7/o534Gq6pEwojSX5G3eTK5jkS49606	intact-crc:BC8326A435AF98BE|rigid:G2XAZGFUMwytbPs0/CVD4fjo6d0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P08670	uniprotkb:A0A2U2GX38	intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|ensembl:ENSP00000224237.5|ensembl:ENSP00000446007.1|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4	intact:EBI-2841288|uniprotkb:A0A0H2W637|uniprotkb:Q74SI0|uniprotkb:A0A384LBC5|uniprotkb:Q7CJG2|uniprotkb:A0A380PEL1	psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short)	psi-mi:a0a2u2gx38_yerpe(display_long)|uniprotkb:YPO2999(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850637|imex:IM-13779-5483	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:675396""|ensembl:ENSG00000026025.16(gene)|ensembl:ENST00000224237.9(transcript)|ensembl:ENST00000544301.7(transcript)|go:""GO:0003725""(double-stranded RNA binding)|go:""GO:0005200""(structural constituent of cytoskeleton)|go:""GO:0005212""(structural constituent of eye lens)|go:""GO:0005737""(cytoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005882""(intermediate filament)|go:""GO:0005886""(plasma membrane)|go:""GO:0005925""(focal adhesion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010977""(negative regulation of neuron projection development)|go:""GO:0014002""(astrocyte development)|go:""GO:0016363""(nuclear matrix)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030424""(axon)|go:""GO:0031175""(neuron projection development)|go:""GO:0031252""(cell leading edge)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0045109""(intermediate filament organization)|go:""GO:0045111""(intermediate filament cytoskeleton)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070307""(lens fiber cell development)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071225""(cellular response to muramyl dipeptide)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0097110""(scaffold protein binding)|go:""GO:1990254""(keratin filament binding)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|interpro:IPR050405|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|rcsb pdb:8RVE|rcsb pdb:8TRQ|rcsb pdb:8TRR|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:NP_003371.2|refseq:XP_006717563.1|efo:""Orphanet:98984""|dip:DIP-32507N|panther:PTHR45652(orthology-group)"	"interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|refseq:YP_002347923.1|go:""GO:0019898""(extrinsic component of membrane)|go:""GO:0022857""(transmembrane transporter activity)|go:""GO:0030313""(cell envelope)|go:""GO:1990195""(macrolide transmembrane transporter complex)|go:""GO:1990961""(xenobiotic detoxification by transmembrane export across the plasma membrane)|refseq:WP_002208495.1|interpro:IPR030190"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/25	rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606	rogid:sdWXUSDDDoa4ne7FHbQ56e9RFP4632	intact-crc:C46916CAE138042D|rigid:9xLyvGjtnIWf8DslA28NEGorEDA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YGH4	uniprotkb:Q00341	intact:EBI-2842137|uniprotkb:Q0WF29|uniprotkb:Q7CIG0	intact:EBI-1049478|uniprotkb:Q9UCY3|uniprotkb:Q53QU2|uniprotkb:B4DTQ2|uniprotkb:E7EM71|ensembl:ENSP00000312042.4|ensembl:ENSP00000375836.1|ensembl:ENSP00000375837.2|intact:EBI-28974616	psi-mi:a0a5p8ygh4_yerpe(display_long)|uniprotkb:YPO2131(locus name)	psi-mi:vigln_human(display_long)|uniprotkb:High density lipoprotein-binding protein(gene name synonym)|uniprotkb:HDLBP(gene name)|psi-mi:HDLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:VGL(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850656|imex:IM-13779-5482	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR015406(Protein of unknown function DUF1983)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032876|refseq:WP_002211698.1|interpro:IPR036116|refseq:YP_002347109.1|interpro:IPR053171|panther:PTHR36251(orthology-group)	"refseq:NP_005327.1|refseq:NP_976221.1|refseq:NP_001230829.1|refseq:XP_016859429.1|ensembl:ENSG00000115677.18(gene)|ensembl:ENST00000310931.10(transcript)|ensembl:ENST00000391975.5(transcript)|ensembl:ENST00000391976.6(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006869""(lipid transport)|go:""GO:0008203""(cholesterol metabolic process)|go:""GO:0008289""(lipid binding)|go:""GO:0034364""(high-density lipoprotein particle)|go:""GO:0045296""(cadherin binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q00341|rcsb pdb:1VIG|rcsb pdb:1VIH|rcsb pdb:2CTE|rcsb pdb:2CTF|rcsb pdb:2CTJ|rcsb pdb:2CTK|rcsb pdb:2CTL|rcsb pdb:2CTM|reactome:R-HSA-8964011|refseq:NP_001307894.1|refseq:NP_001307895.1|refseq:XP_005247059.2|refseq:XP_006712538.1|refseq:XP_011509360.1|refseq:XP_011509362.1|refseq:XP_005247060.2|panther:PTHR10627(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oOCFMN5J0JyZf3JZhYlAIr4sCxM632	rogid:7/o534Gq6pEwojSX5G3eTK5jkS49606	intact-crc:A3EB42811A0CA88E|rigid:QeuAqP1HdflsODA4K42mJnoDXE0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96JH7	uniprotkb:Q8ZA76	intact:EBI-1995920|ensembl:ENSP00000309031.4|uniprotkb:Q504T4|uniprotkb:Q86T93|uniprotkb:Q86W01|uniprotkb:Q8N3A9|uniprotkb:Q9H5R8	intact:EBI-2846943|uniprotkb:Q0WA76	psi-mi:vcip1_human(display_long)|uniprotkb:VCPIP1(gene name)|psi-mi:VCPIP1(display_short)|uniprotkb:KIAA1850(gene name synonym)|uniprotkb:VCIP135(gene name synonym)|uniprotkb:Valosin-containing protein p97/p47 complex-interacting protein p135(gene name synonym)|uniprotkb:Valosin-containing protein p97/p47 complex-interacting protein 1(gene name synonym)	psi-mi:glgx_yerpe(display_long)|uniprotkb:glgX(gene name)|psi-mi:glgX(display_short)|uniprotkb:Limit dextrin alpha-1,6-maltotetraose-hydrolase(gene name synonym)|uniprotkb:YPO3941(locus name)|uniprotkb:YP_3303(locus name)|uniprotkb:y3887(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850670|imex:IM-13779-5481	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_079330.2|ensembl:ENSG00000175073.8(gene)|ensembl:ENST00000310421.5(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005795""(Golgi stack)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016320""(endoplasmic reticulum membrane fusion)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0035871""(protein K11-linked deubiquitination)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:0090168""(Golgi reassembly)|go:""GO:0106300""(protein-DNA covalent cross-linking repair)|go:""GO:1905634""(regulation of protein localization to chromatin)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR029071|interpro:IPR039087|interpro:IPR045827|interpro:IPR048857|mint:Q96JH7|rcsb pdb:8YKA|reactome:R-HSA-5689896|panther:PTHR14843(orthology-group)"	"interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR022844|interpro:IPR011837(Glycogen debranching enzyme GlgX)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR040784|go:""GO:0004133""(obsolete glycogen debranching enzyme activity)|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005980""(glycogen catabolic process)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|refseq:WP_002209499.1|interpro:IPR044505|refseq:YP_002348812.1|panther:PTHR43002(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EMqKXIMqv42Vlg5oUS+kT9WI5BQ9606	rogid:8sHtj0obGqvrIdGE1JWk8okcbRM632	intact-crc:71296E789DD2B996|rigid:zbOvWOueXxvwJhZq4FBalFhhTRc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GUX9	uniprotkb:Q96JH7	intact:EBI-2841416|uniprotkb:A0A0H2W940|uniprotkb:Q74PB0|uniprotkb:A0A384LLI5|uniprotkb:Q7CFN3|uniprotkb:A0A3N4BJ32	intact:EBI-1995920|ensembl:ENSP00000309031.4|uniprotkb:Q504T4|uniprotkb:Q86T93|uniprotkb:Q86W01|uniprotkb:Q8N3A9|uniprotkb:Q9H5R8	psi-mi:a0a2u2gux9_yerpe(display_long)|uniprotkb:YPO4108(locus name)	psi-mi:vcip1_human(display_long)|uniprotkb:VCPIP1(gene name)|psi-mi:VCPIP1(display_short)|uniprotkb:KIAA1850(gene name synonym)|uniprotkb:VCIP135(gene name synonym)|uniprotkb:Valosin-containing protein p97/p47 complex-interacting protein p135(gene name synonym)|uniprotkb:Valosin-containing protein p97/p47 complex-interacting protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850663|imex:IM-13779-5480	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR041492|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|go:""GO:0016787""(hydrolase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002215575.1|refseq:YP_002348959.1|interpro:IPR023198|interpro:IPR036412|interpro:IPR051600"	"refseq:NP_079330.2|ensembl:ENSG00000175073.8(gene)|ensembl:ENST00000310421.5(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005795""(Golgi stack)|go:""GO:0006508""(proteolysis)|go:""GO:0006974""(DNA damage response)|go:""GO:0016320""(endoplasmic reticulum membrane fusion)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0035871""(protein K11-linked deubiquitination)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:0090168""(Golgi reassembly)|go:""GO:0106300""(protein-DNA covalent cross-linking repair)|go:""GO:1905634""(regulation of protein localization to chromatin)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR029071|interpro:IPR039087|interpro:IPR045827|interpro:IPR048857|mint:Q96JH7|rcsb pdb:8YKA|reactome:R-HSA-5689896|panther:PTHR14843(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:N4DmZVhdbeJX1EvnC462dwFiaNU632	rogid:EMqKXIMqv42Vlg5oUS+kT9WI5BQ9606	intact-crc:8516927543C96099|rigid:9bMW89E+dMWcY72K5eFsZEYgJDo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95292	uniprotkb:Q0WDK1	intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175.1	intact:EBI-2850684|uniprotkb:Q74ST1|uniprotkb:A0A0H2W551|uniprotkb:A0A5P8YJE0|uniprotkb:Q7CJR5|uniprotkb:A0A384L7X2	psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	psi-mi:q0wdk1_yerpe(display_long)|uniprotkb:kdpD(gene name)|psi-mi:kdpD(display_short)|uniprotkb:YPO2689(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850689|imex:IM-13779-5487	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR10809(orthology-group)|dip:DIP-39816N|efo:""Orphanet:209335""|efo:""Orphanet:803""|ensembl:ENSG00000124164.16(gene)|ensembl:ENST00000475243.6(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0008017""(microtubule binding)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019899""(enzyme binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0036498""(IRE1-mediated unfolded protein response)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0044830""(modulation by host of viral RNA genome replication)|go:""GO:0045070""(positive regulation of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046725""(negative regulation by virus of viral protein levels in host cell)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0090114""(COPII-coated vesicle budding)|go:""GO:0090158""(endoplasmic reticulum membrane organization)|go:""GO:0098793""(presynapse)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|refseq:NP_001182606.1|refseq:NP_004729.1"	"interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR027417|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003852(Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal)|interpro:IPR029016|interpro:IPR025201|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016020""(membrane)|interpro:IPR038318|interpro:IPR036097|interpro:IPR036890|refseq:WP_002209649.1|refseq:YP_002347637.1|interpro:IPR052023"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606	rogid:Fbp8vVsab8EtVWWrBsbzda/Mi7I632	intact-crc:863FD744F1FAA92D|rigid:Wq7tSSxP9LRxhUnNBzfWRAirbc4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P0L0	uniprotkb:A0A5P8YLF8	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880.3	intact:EBI-2850706|uniprotkb:Q74PL3|uniprotkb:A0A0H2W9K4|uniprotkb:Q0WAZ5|uniprotkb:Q7CL61|uniprotkb:A0A384L870	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:a0a5p8ylf8_yerpe(display_long)|uniprotkb:yhdT(gene name)|psi-mi:yhdT(display_short)|uniprotkb:YPO3657a(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850711|imex:IM-13779-5486	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003565.4|refseq:NP_919415.2|ensembl:ENSG00000101558.14(gene)|ensembl:ENST00000400000.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031982""(vesicle)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035627""(ceramide transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0061025""(membrane fusion)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0090114""(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|dip:DIP-41135N|panther:PTHR10809(orthology-group)"	interpro:IPR010398(Protein of unknown function DUF997)|refseq:WP_002210066.1|refseq:YP_002348543.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	rogid:AO/pOgxvhx50gpHLovmUVr/2MH0632	intact-crc:ACB65DC64D4B822A|rigid:8j9bJepGjkS5d/22nFtsDVCDps8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3V1M0	uniprotkb:P50552	intact:EBI-2845264	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|ensembl:ENSP00000245932.5|intact:EBI-28992147	psi-mi:a0a6b3v1m0_yerpe(display_long)|uniprotkb:aspA(gene name)|psi-mi:aspA(display_short)|uniprotkb:y0606(locus name)	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850677|imex:IM-13779-5484	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000362(Fumarate lyase)|interpro:IPR004708(Aspartate ammonia-lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|uniprotkb:A0A6B3T134(uniprot-removed-ac)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006531""(aspartate metabolic process)|go:""GO:0008797""(aspartate ammonia-lyase activity)|interpro:IPR051546|refseq:WP_002232006.1"	"refseq:NP_003361.1|ensembl:ENSG00000125753.15(gene)|ensembl:ENST00000245932.11(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0003779""(actin binding)|go:""GO:0005522""(profilin binding)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007411""(axon guidance)|go:""GO:0008154""(actin polymerization or depolymerization)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0017124""(SH3 domain binding)|go:""GO:0030838""(positive regulation of actin filament polymerization)|go:""GO:0031258""(lamellipodium membrane)|go:""GO:0031527""(filopodium membrane)|go:""GO:0045296""(cadherin binding)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0070062""(extracellular exosome)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|mint:P50552|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR038023|rcsb pdb:1EGX|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:8GAT|rcsb pdb:8GAU|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N|panther:PTHR11202(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:PXsqlchUuJ1rg+UhVo5m7cCj6c0632	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	intact-crc:BA3F0233952B2A5B|rigid:6xbem4Kr0XbkOrc9j/niwgWyivI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WKD0	uniprotkb:Q9P0L0	intact:EBI-2842319|uniprotkb:Q74Y13|uniprotkb:A0A0H2W227|uniprotkb:Q7CFV4|uniprotkb:A0A2U2GZH9|uniprotkb:A0A384KL53	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880.3	psi-mi:q0wkd0_yerpe(display_long)|uniprotkb:YPO0174(locus name)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850718|imex:IM-13779-5488	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010020(Integral membrane protein, YccS/YhfK)|interpro:IPR032692|go:""GO:0005886""(plasma membrane)|refseq:WP_002212296.1|refseq:YP_002345258.1|interpro:IPR049453"	"refseq:NP_003565.4|refseq:NP_919415.2|ensembl:ENSG00000101558.14(gene)|ensembl:ENST00000400000.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031982""(vesicle)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035627""(ceramide transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0061025""(membrane fusion)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0090114""(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|dip:DIP-41135N|panther:PTHR10809(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:kcGMu3nqgZZDLIKTmhYWFPzUBcc632	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	intact-crc:0ADFF6630EBB9C5C|rigid:3Dxo12VN19zB8VH1RR20PxiHlbA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9P0L0	uniprotkb:Q8D1S0	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880.3	intact:EBI-2850696	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:q8d1s0_yerpe(display_long)|uniprotkb:y0107(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850699|imex:IM-13779-5485	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003565.4|refseq:NP_919415.2|ensembl:ENSG00000101558.14(gene)|ensembl:ENST00000400000.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0006686""(sphingomyelin biosynthetic process)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0008017""(microtubule binding)|go:""GO:0015630""(microtubule cytoskeleton)|go:""GO:0015914""(phospholipid transport)|go:""GO:0015918""(sterol transport)|go:""GO:0019076""(viral release from host cell)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030301""(cholesterol transport)|go:""GO:0031175""(neuron projection development)|go:""GO:0031965""(nuclear membrane)|go:""GO:0031982""(vesicle)|go:""GO:0033149""(FFAT motif binding)|go:""GO:0035577""(azurophil granule membrane)|go:""GO:0035627""(ceramide transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0044828""(negative regulation by host of viral genome replication)|go:""GO:0044829""(positive regulation by host of viral genome replication)|go:""GO:0045296""(cadherin binding)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0061025""(membrane fusion)|go:""GO:0061817""(endoplasmic reticulum-plasma membrane tethering)|go:""GO:0070972""(protein localization to endoplasmic reticulum)|go:""GO:0090114""(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|dip:DIP-41135N|panther:PTHR10809(orthology-group)"	"interpro:IPR006042(Xanthine/uracil permease)|interpro:IPR006043(Xanthine/uracil/vitamin C permease)|interpro:IPR017588(Xanthine permease)|go:""GO:0005886""(plasma membrane)|go:""GO:0015205""(nucleobase transmembrane transporter activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/05	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	rogid:pThHQ2zrzeQ5+fSV40k1VQRiMpI632	intact-crc:99D8FA0B86BFD5FC|rigid:FPAVjo0UAk5quNIs2y2hpHkaMRQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CHU1	uniprotkb:Q9UBK9	intact:EBI-2841165|uniprotkb:Q74V60	intact:EBI-357355|uniprotkb:B2R561|uniprotkb:Q5JZG3|uniprotkb:Q9Y6E5|ensembl:ENSP00000327797.3|uniprotkb:A0A0C4DFR8	psi-mi:mtfa_yerpe(display_long)|uniprotkb:mtfA(gene name)|psi-mi:mtfA(display_short)|uniprotkb:Probable zinc metallopeptidase MtfA(gene name synonym)|uniprotkb:YPO1732(locus name)|uniprotkb:YP_1472(locus name)|uniprotkb:y2576(locus name)	psi-mi:uxt_human(display_long)|uniprotkb:UXT(gene name)|psi-mi:UXT(display_short)|uniprotkb:HSPC024(orf name)|uniprotkb:Ubiquitously expressed transcript protein(gene name synonym)|uniprotkb:Androgen receptor trapped clone 27 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850749|imex:IM-13779-5492	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002346732.1|interpro:IPR024079|interpro:IPR010384(Protein of unknown function DUF980)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|refseq:WP_002211042.1|interpro:IPR042252|panther:PTHR30164(orthology-group)"	"refseq:NP_004173.1|refseq:NP_705582.1|ensembl:ENSG00000126756.12(gene)|ensembl:ENST00000333119.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000922""(spindle pole)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006915""(apoptotic process)|go:""GO:0007098""(centrosome cycle)|go:""GO:0008017""(microtubule binding)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|interpro:IPR003994(Prefoldin related, ubiquitously expressed transcript)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|mint:Q9UBK9|reactome:R-HSA-8953750|panther:PTHR13345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3PKDmcLXdDD+p8B4M6novftNc7A632	rogid:XhE14Q7CfwVXxJ4fTiRQTm3Idvk9606	intact-crc:EC1111C8DEC2EF7F|rigid:WsEpRlNF4vMiwu0uaq5DVNse5sM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4AWL6	uniprotkb:P46939	intact:EBI-2839922|uniprotkb:Q74PS8|uniprotkb:A0A0H2W8P4|uniprotkb:Q7CL98|uniprotkb:A0A384KVQ8	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|ensembl:ENSP00000356515.3|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40	psi-mi:a0a3n4awl6_yerpe(display_long)|uniprotkb:arcB(gene name)|psi-mi:arcB(display_short)|uniprotkb:YPO3555(locus name)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850768|imex:IM-13779-5491	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR008207(""Signal transduction histidine kinase, phosphotransfer (Hpt) region"")|interpro:IPR014409(Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR027460|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR040642|refseq:WP_002210142.1|interpro:IPR035965|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|refseq:YP_002348442.1|panther:PTHR43719(orthology-group)"	"ensembl:ENSG00000152818.20(gene)|ensembl:ENST00000367545.8(transcript)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006936""(muscle contraction)|go:""GO:0007517""(muscle organ development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016020""(membrane)|go:""GO:0017166""(vinculin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030175""(filopodium)|go:""GO:0031527""(filopodium membrane)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042383""(sarcolemma)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0099536""(synaptic signaling)|go:""GO:2000649""(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|interpro:IPR050774|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665|refseq:NP_009055.2|refseq:XP_005267187.1|refseq:XP_011534408.1|dip:DIP-711N|panther:PTHR12268(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:2Xj+2T9RNcjzPI8FYYaZmDGKNBk632	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	intact-crc:4C2508286850E64A|rigid:oRVbvUvk7xRH9sABM9fRl8VwoI4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCK0	uniprotkb:P46939	intact:EBI-2850756|uniprotkb:Q0WCT0	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|ensembl:ENSP00000356515.3|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40	psi-mi:sye_yerpe(display_long)|uniprotkb:gltX(gene name)|psi-mi:gltX(display_short)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO2984(locus name)|uniprotkb:YP_2609(locus name)|uniprotkb:y1498(locus name)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850761|imex:IM-13779-5490	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004527(Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020058|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:WP_002222185.1|go:""GO:0000049""(tRNA binding)|go:""GO:0004818""(glutamate-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006424""(glutamyl-tRNA aminoacylation)|go:""GO:0008270""(zinc ion binding)|interpro:IPR033910|refseq:YP_002347908.1|interpro:IPR049940|interpro:IPR045462|panther:PTHR43311(orthology-group)"	"ensembl:ENSG00000152818.20(gene)|ensembl:ENST00000367545.8(transcript)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006936""(muscle contraction)|go:""GO:0007517""(muscle organ development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016020""(membrane)|go:""GO:0017166""(vinculin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030175""(filopodium)|go:""GO:0031527""(filopodium membrane)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042383""(sarcolemma)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0099536""(synaptic signaling)|go:""GO:2000649""(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|interpro:IPR050774|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665|refseq:NP_009055.2|refseq:XP_005267187.1|refseq:XP_011534408.1|dip:DIP-711N|panther:PTHR12268(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:mgEcXw+y7R2H2GcuN33S322DZKA632	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	intact-crc:8BA3A6915B981DF3|rigid:yoXM4q7HD7a6FjHzvecCvM/vviQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZEG8	uniprotkb:Q9UBK9	intact:EBI-2850725|uniprotkb:Q0WEW2	intact:EBI-357355|uniprotkb:B2R561|uniprotkb:Q5JZG3|uniprotkb:Q9Y6E5|ensembl:ENSP00000327797.3|uniprotkb:A0A0C4DFR8	psi-mi:trpc_yerpe(display_long)|uniprotkb:YPO2205(locus name)|uniprotkb:y2049(locus name)|uniprotkb:YP_2003(locus name)|uniprotkb:trpC(gene name)|psi-mi:trpC(display_short)	psi-mi:uxt_human(display_long)|uniprotkb:UXT(gene name)|psi-mi:UXT(display_short)|uniprotkb:HSPC024(orf name)|uniprotkb:Ubiquitously expressed transcript protein(gene name synonym)|uniprotkb:Androgen receptor trapped clone 27 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850730|imex:IM-13779-5493	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR013798(Indole-3-glycerol phosphate synthase)|interpro:IPR001468(Indole-3-glycerol phosphate synthase, central region)|interpro:IPR001240(""N-(5'phosphoribosyl)anthranilate isomerase (PRAI)"")|interpro:IPR011060(Ribulose-phosphate binding barrel)|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004425""(indole-3-glycerol-phosphate synthase activity)|go:""GO:0004640""(phosphoribosylanthranilate isomerase activity)|go:""GO:0006568""(L-tryptophan metabolic process)|refseq:WP_002210632.1|refseq:YP_002347176.1|interpro:IPR045186|panther:PTHR22854(orthology-group)"	"refseq:NP_004173.1|refseq:NP_705582.1|ensembl:ENSG00000126756.12(gene)|ensembl:ENST00000333119.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000922""(spindle pole)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006915""(apoptotic process)|go:""GO:0007098""(centrosome cycle)|go:""GO:0008017""(microtubule binding)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|interpro:IPR003994(Prefoldin related, ubiquitously expressed transcript)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|mint:Q9UBK9|reactome:R-HSA-8953750|panther:PTHR13345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tXJCmgIVZ8neuY4xm84rcCGGyFA632	rogid:XhE14Q7CfwVXxJ4fTiRQTm3Idvk9606	intact-crc:F86B79D8037C9E0B|rigid:c56YInW3/QWhcM8zfSr+TRFo4yg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BIX1	uniprotkb:Q9UBK9	intact:EBI-2850740|uniprotkb:Q74QE5|uniprotkb:Q0WIJ5|uniprotkb:Q7CGW7|uniprotkb:A0A384K8D1	intact:EBI-357355|uniprotkb:B2R561|uniprotkb:Q5JZG3|uniprotkb:Q9Y6E5|ensembl:ENSP00000327797.3|uniprotkb:A0A0C4DFR8	psi-mi:a0a3n4bix1_yerpe(display_long)|uniprotkb:YPO0842(locus name)	psi-mi:uxt_human(display_long)|uniprotkb:UXT(gene name)|psi-mi:UXT(display_short)|uniprotkb:HSPC024(orf name)|uniprotkb:Ubiquitously expressed transcript protein(gene name synonym)|uniprotkb:Androgen receptor trapped clone 27 protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850737|imex:IM-13779-5489	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR024607|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR000917(Sulphatase)|refseq:WP_002209886.1|go:""GO:0004065""(arylsulfatase activity)|refseq:YP_002345893.1|interpro:IPR050738|panther:PTHR42693(orthology-group)"	"refseq:NP_004173.1|refseq:NP_705582.1|ensembl:ENSG00000126756.12(gene)|ensembl:ENST00000333119.8(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000226""(microtubule cytoskeleton organization)|go:""GO:0000922""(spindle pole)|go:""GO:0003682""(chromatin binding)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005813""(centrosome)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006915""(apoptotic process)|go:""GO:0007098""(centrosome cycle)|go:""GO:0008017""(microtubule binding)|go:""GO:0047497""(mitochondrion transport along microtubule)|go:""GO:0048487""(beta-tubulin binding)|go:""GO:0050821""(protein stabilization)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1990062""(RPAP3/R2TP/prefoldin-like complex)|interpro:IPR003994(Prefoldin related, ubiquitously expressed transcript)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|mint:Q9UBK9|reactome:R-HSA-8953750|panther:PTHR13345(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:r3Gn5oncgLuEpVsulR2xKRUgpT8632	rogid:XhE14Q7CfwVXxJ4fTiRQTm3Idvk9606	intact-crc:68DA49FFB261BB96|rigid:Yg7hkCu9Lu/NDuKXdWTGHG5Im3E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARH5	uniprotkb:P46939	intact:EBI-2850782|uniprotkb:A0A384LM42|uniprotkb:Q74YZ4|uniprotkb:Q7BTW9|uniprotkb:A0A2U2GUV4|uniprotkb:A0A0H2W142|uniprotkb:A0A5P8YM77	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|ensembl:ENSP00000356515.3|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40	psi-mi:q7arh5_yerpe(display_long)|uniprotkb:repB(gene name)|psi-mi:repB(display_short)|uniprotkb:Y0003(gene name synonym)|uniprotkb:copB(gene name synonym)|uniprotkb:repA2(gene name synonym)|uniprotkb:YPCD1.79c(locus name)	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850786|imex:IM-13779-5497	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_857774.1|refseq:NP_857902.1|interpro:IPR019661|refseq:NP_395212.1|refseq:WP_002229817.1|go:""GO:0003677""(DNA binding)|go:""GO:0006276""(plasmid maintenance)"	"ensembl:ENSG00000152818.20(gene)|ensembl:ENST00000367545.8(transcript)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006936""(muscle contraction)|go:""GO:0007517""(muscle organ development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016020""(membrane)|go:""GO:0017166""(vinculin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030175""(filopodium)|go:""GO:0031527""(filopodium membrane)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042383""(sarcolemma)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0099536""(synaptic signaling)|go:""GO:2000649""(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|interpro:IPR050774|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665|refseq:NP_009055.2|refseq:XP_005267187.1|refseq:XP_011534408.1|dip:DIP-711N|panther:PTHR12268(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:4p+pRzaBGQfQDlXyLZ7sCygrk+g632	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	intact-crc:1850286385B7FFFA|rigid:MuPZqefEjYuKhX0d9th/tSR14JA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00507	uniprotkb:A0A3N4AWI2	intact:EBI-2322142|uniprotkb:O14601|intact:EBI-28977565|ensembl:ENSP00000342812.3|ensembl:ENSP00000498372.1	intact:EBI-2850800|uniprotkb:Q74PQ4|uniprotkb:Q0WB69|uniprotkb:Q7CL85|uniprotkb:A0A384LA61	psi-mi:usp9y_human(display_long)|uniprotkb:USP9Y(gene name)|psi-mi:USP9Y(display_short)|uniprotkb:DFFRY(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-Y(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-Y(gene name synonym)|uniprotkb:Fat facets protein-related, Y-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, Y chromosome(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-Y(gene name synonym)	psi-mi:a0a3n4awi2_yerpe(display_long)|uniprotkb:ntrA(gene name synonym)|uniprotkb:rpoN(gene name synonym)|uniprotkb:YPO3582(locus name)|uniprotkb:glnF(gene name)|psi-mi:glnF(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850805|imex:IM-13779-5496	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000114374.13(gene)|ensembl:ENST00000338981.7(transcript)|ensembl:ENST00000651177.1(transcript)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0008234""(cysteine-type peptidase activity)|go:""GO:0016477""(cell migration)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0031647""(regulation of protein stability)|go:""GO:0046872""(metal ion binding)|go:""GO:0070410""(co-SMAD binding)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR038765|interpro:IPR050164|interpro:IPR055176|mint:O00507|refseq:NP_004645.2|efo:""Orphanet:1646""|panther:PTHR24006(orthology-group)"	"interpro:IPR000394(RNA polymerase sigma factor 54)|interpro:IPR007046(RNA polymerase sigma factor 54, core-binding)|interpro:IPR007634(RNA polymerase sigma factor 54, DNA-binding)|refseq:WP_002210115.1|go:""GO:0000428""(DNA-directed RNA polymerase complex)|go:""GO:0001216""(DNA-binding transcription activator activity)|go:""GO:0003677""(DNA binding)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016779""(nucleotidyltransferase activity)|go:""GO:0016987""(sigma factor activity)|interpro:IPR038709|refseq:YP_002348469.1|panther:PTHR32248(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hUnNhsQfcbxhAccrjno5b0wRSSA9606	rogid:zdzEhy+OLn0kaYS9XKuSOj5MMBM632	intact-crc:FB360AFC60AC07AB|rigid:pyJ2/eM2iokFlWwvQj3ftwd5G1M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60763	uniprotkb:A0A2U2GYS8	intact:EBI-356164|uniprotkb:B2RAQ0|uniprotkb:Q6PK63|uniprotkb:Q8N592|uniprotkb:Q86TB8|ensembl:ENSP00000444850.2|intact:EBI-21358067	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	psi-mi:uso1_human(display_long)|uniprotkb:USO1(gene name)|psi-mi:USO1(display_short)|uniprotkb:VDP(gene name synonym)|uniprotkb:Protein USO1 homolog(gene name synonym)|uniprotkb:Transcytosis-associated protein(gene name synonym)|uniprotkb:Vesicle-docking protein(gene name synonym)	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850812|imex:IM-13779-5498	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003706.2|refseq:NP_001276978.1|ensembl:ENSG00000138768.15(gene)|ensembl:ENST00000514213.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001650""(fibrillar center)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005795""(Golgi stack)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030133""(transport vesicle)|go:""GO:0032252""(secretory granule localization)|go:""GO:0045056""(transcytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0048211""(Golgi vesicle docking)|go:""GO:0048280""(vesicle fusion with Golgi apparatus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061025""(membrane fusion)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|interpro:IPR000225(Armadillo)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024095|interpro:IPR041209|mint:O60763|rcsb pdb:2W3C|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|panther:PTHR10013(orthology-group)"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qrBH7A4Ce+01K9Mu8cdVqMYUh4M9606	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	intact-crc:C1807BA0DD3863E1|rigid:Nz/CgWSbjuqAGXQsDpo/LyyGudg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P46939	uniprotkb:A0A2U2H1F2	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|ensembl:ENSP00000356515.3|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40	intact:EBI-2841615|uniprotkb:Q74SB6|uniprotkb:A0A384KAD8|uniprotkb:A0A0H2W6F9|uniprotkb:Q7CJK4|uniprotkb:A0A5P8YI72	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:a0a2u2h1f2_yerpe(display_long)|uniprotkb:mgtE(gene name)|psi-mi:mgtE(display_short)|uniprotkb:YPO2839(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850775|imex:IM-13779-5494	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000152818.20(gene)|ensembl:ENST00000367545.8(transcript)|go:""GO:0001954""(positive regulation of cell-matrix adhesion)|go:""GO:0003779""(actin binding)|go:""GO:0005178""(integrin binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005886""(plasma membrane)|go:""GO:0006936""(muscle contraction)|go:""GO:0007517""(muscle organ development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016010""(dystrophin-associated glycoprotein complex)|go:""GO:0016020""(membrane)|go:""GO:0017166""(vinculin binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030175""(filopodium)|go:""GO:0031527""(filopodium membrane)|go:""GO:0031594""(neuromuscular junction)|go:""GO:0032991""(protein-containing complex)|go:""GO:0042383""(sarcolemma)|go:""GO:0045211""(postsynaptic membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0099536""(synaptic signaling)|go:""GO:2000649""(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|interpro:IPR050774|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665|refseq:NP_009055.2|refseq:XP_005267187.1|refseq:XP_011534408.1|dip:DIP-711N|panther:PTHR12268(orthology-group)"	"interpro:IPR000644(Cystathionine beta-synthase, core)|refseq:WP_002209784.1|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|go:""GO:0005886""(plasma membrane)|go:""GO:0015095""(magnesium ion transmembrane transporter activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR038076|refseq:YP_002347777.1|interpro:IPR036739|interpro:IPR046342"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rogid:11g3VjbBA3GhZc1D28cRbMzugdw632	intact-crc:5731A9A2EA4187B1|rigid:zKzCWdSwjEehOuuO2vQdcrtlT6g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B652	uniprotkb:Q9NYH9	intact:EBI-2841456|uniprotkb:Q74UD2|uniprotkb:A0A0H2W5A2|uniprotkb:Q7CIY7	intact:EBI-749211|uniprotkb:Q8IX96|uniprotkb:Q96BL2|uniprotkb:Q9NQ91|ensembl:ENSP00000261708.4	psi-mi:a0a3n4b652_yerpe(display_long)|uniprotkb:cheA(gene name)|psi-mi:cheA(display_short)|uniprotkb:YPO1666(locus name)	psi-mi:utp6_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated antigen 66(gene name synonym)|uniprotkb:Multiple hat domains protein(gene name synonym)|uniprotkb:UTP6(gene name)|psi-mi:UTP6(display_short)|uniprotkb:C17orf40(gene name synonym)|uniprotkb:HCA66(gene name synonym)|uniprotkb:MHAT(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850793|imex:IM-13779-5495	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR002545(CheW-like protein)|interpro:IPR015162(CheY binding)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR008207(""Signal transduction histidine kinase, phosphotransfer (Hpt) region"")|interpro:IPR004105(Signal transduction histidine kinase, subgroup, homodimeric)|interpro:IPR005467(Signal transduction histidine kinase, core)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006935""(chemotaxis)|refseq:YP_002346673.1|interpro:IPR035891|interpro:IPR036061|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037006|interpro:IPR051315|panther:PTHR43395(orthology-group)"	"refseq:NP_060898.2|ensembl:ENSG00000108651.10(gene)|ensembl:ENST00000261708.9(transcript)|go:""GO:0000462""(""maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005694""(chromosome)|go:""GO:0005730""(nucleolus)|go:""GO:0030515""(snoRNA binding)|go:""GO:0032040""(small-subunit processome)|go:""GO:0034388""(Pwp2p-containing subcomplex of 90S preribosome)|go:""GO:0042274""(ribosomal small subunit biogenesis)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013949(U3 small nucleolar RNA-associated protein 6)|mint:Q9NYH9|rcsb pdb:7MQ8|rcsb pdb:7MQ9|rcsb pdb:7MQA|reactome:R-HSA-6790901|reactome:R-HSA-6791226|panther:PTHR23271(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:KztfI7bmNuR6U1Zo6bOZct0DtBc632	rogid:hMKHMRXUFqGjWKsyi9MedHMilhc9606	intact-crc:97C8B8DCA88008E0|rigid:oxM/It1T5VfSuQrPsaawTQjThcA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q74R28	uniprotkb:Q86UX7	intact:EBI-2844649|uniprotkb:Q8D1I8	intact:EBI-373158|uniprotkb:Q8IUA1|uniprotkb:Q8N207|uniprotkb:Q9BT48|ensembl:ENSP00000279227.5|ensembl:ENSP00000513988.1	psi-mi:ugpc_yerpe(display_long)|uniprotkb:ugpC(gene name)|psi-mi:ugpC(display_short)|uniprotkb:YPO3793(locus name)|uniprotkb:y0437(locus name)|uniprotkb:YP_3256(locus name)	psi-mi:urp2_human(display_long)|uniprotkb:FERMT3(gene name)|psi-mi:FERMT3(display_short)|uniprotkb:KIND3(gene name synonym)|uniprotkb:MIG2B(gene name synonym)|uniprotkb:URP2(gene name synonym)|uniprotkb:Unc-112-related protein 2(gene name synonym)|uniprotkb:Kindlin-3(gene name synonym)|uniprotkb:MIG2-like protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850850|imex:IM-13779-5500	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR040582|interpro:IPR015855(ABC transporter, maltose/maltodextrin import, MalK)|interpro:IPR027417|refseq:WP_002211523.1|go:""GO:0001407""(glycerophosphodiester transmembrane transport)|go:""GO:0005524""(ATP binding)|go:""GO:0008643""(carbohydrate transport)|go:""GO:0015430""(ABC-type glycerol-3-phosphate transporter activity)|go:""GO:0015794""(glycerol-3-phosphate transmembrane transport)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0055052""(""ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing"")|interpro:IPR047641|refseq:YP_002348670.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR43875(orthology-group)"	"efo:""Orphanet:99844""|ensembl:ENSG00000149781.14(gene)|ensembl:ENST00000279227.10(transcript)|ensembl:ENST00000698860.1(transcript)|go:""GO:0002102""(podosome)|go:""GO:0005178""(integrin binding)|go:""GO:0005576""(extracellular region)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0007229""(integrin-mediated signaling pathway)|go:""GO:0008289""(lipid binding)|go:""GO:0016020""(membrane)|go:""GO:0030055""(cell-substrate junction)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0033622""(integrin activation)|go:""GO:0033632""(regulation of cell-cell adhesion mediated by integrin)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0042995""(cell projection)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070527""(platelet aggregation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR037837|interpro:IPR037843|interpro:IPR040790|mint:Q86UX7|rcsb pdb:2YS3|rcsb pdb:6V97|rcsb pdb:6V9G|rcsb pdb:7C3M|reactome:R-HSA-114608|refseq:NP_113659.3|refseq:NP_848537.1|refseq:XP_011543596.1|refseq:XP_016873887.1|panther:PTHR16160(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NtRUgbRI2HE2UzUkxbSvyMnRkao632	rogid:BDLaeBD6Ycz4HAh/4QlZeSZurxY9606	intact-crc:F70BFA3E15E2264F|rigid:imeQNnjH/dZOy/d3jhkGPwsleEw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BTM9	uniprotkb:A0A2U2GYS8	intact:EBI-714589|uniprotkb:B4DV08|uniprotkb:B3KMH3|uniprotkb:Q5T4B4|ensembl:ENSP00000361944.4	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	psi-mi:urm1_human(display_long)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)|uniprotkb:C9orf74(gene name synonym)	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850857|imex:IM-13779-5501	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001252511.1|refseq:NP_001129419.1|refseq:NP_112176.1|ensembl:ENSG00000167118.11(gene)|ensembl:ENST00000372853.9(transcript)|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0031386""(protein tag activity)|go:""GO:0032447""(protein urmylation)|go:""GO:0034227""(tRNA thio-modification)|go:""GO:0097163""(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|reactome:R-HSA-6782315|dip:DIP-48631N|panther:PTHR14986(orthology-group)"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kxdG8Bgg9IY27mblxTjdosw3vHc9606	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	intact-crc:2A171C9BFE42CCCA|rigid:DJRB1T2cZJHwRu+qukWB1zAJ9GU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZIX0	uniprotkb:O60763	intact:EBI-2843533|uniprotkb:Q0WJU5	intact:EBI-356164|uniprotkb:B2RAQ0|uniprotkb:Q6PK63|uniprotkb:Q8N592|uniprotkb:Q86TB8|ensembl:ENSP00000444850.2|intact:EBI-21358067	psi-mi:rsga_yerpe(display_long)|uniprotkb:rsgA(gene name)|psi-mi:rsgA(display_short)|uniprotkb:YPO0365(locus name)|uniprotkb:y0622(locus name)|uniprotkb:YP_0520(locus name)	psi-mi:uso1_human(display_long)|uniprotkb:USO1(gene name)|psi-mi:USO1(display_short)|uniprotkb:VDP(gene name synonym)|uniprotkb:Protein USO1 homolog(gene name synonym)|uniprotkb:Transcytosis-associated protein(gene name synonym)|uniprotkb:Vesicle-docking protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850819|imex:IM-13779-5503	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010914(EngC GTPase)|interpro:IPR004881(GTPase EngC)|interpro:IPR027417|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0019843""(rRNA binding)|go:""GO:0042274""(ribosomal small subunit biogenesis)|go:""GO:0046872""(metal ion binding)|interpro:IPR030378|refseq:WP_002209142.1|refseq:YP_002345443.1|interpro:IPR012340(Nucleic acid-binding, OB-fold)|panther:PTHR32120(orthology-group)"	"refseq:NP_003706.2|refseq:NP_001276978.1|ensembl:ENSG00000138768.15(gene)|ensembl:ENST00000514213.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001650""(fibrillar center)|go:""GO:0003723""(RNA binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005795""(Golgi stack)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005829""(cytosol)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007264""(small GTPase-mediated signal transduction)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030133""(transport vesicle)|go:""GO:0032252""(secretory granule localization)|go:""GO:0045056""(transcytosis)|go:""GO:0045296""(cadherin binding)|go:""GO:0048211""(Golgi vesicle docking)|go:""GO:0048280""(vesicle fusion with Golgi apparatus)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0061025""(membrane fusion)|go:""GO:1900076""(regulation of cellular response to insulin stimulus)|interpro:IPR000225(Armadillo)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024095|interpro:IPR041209|mint:O60763|rcsb pdb:2W3C|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|panther:PTHR10013(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rH6QCtn1mhukog75yh2CbD5VMPg632	rogid:qrBH7A4Ce+01K9Mu8cdVqMYUh4M9606	intact-crc:9E808CF2BE68E1CF|rigid:8vY7hsgNhs2pB2/x5yTQD9XTX7s	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CHK7	uniprotkb:Q15853	intact:EBI-2850841|uniprotkb:Q74VU8	intact:EBI-1055994|uniprotkb:Q15851|uniprotkb:Q15852|uniprotkb:O00671|uniprotkb:O00709|uniprotkb:Q05750|uniprotkb:Q07952|uniprotkb:Q6FI33|ensembl:ENSP00000222305.2|uniprotkb:Q6YI47	psi-mi:rlmkl_yerpe(display_long)|uniprotkb:YPO1418(locus name)|uniprotkb:y2751(locus name)|uniprotkb:YP_1175(locus name)|uniprotkb:rlmL(gene name)|psi-mi:rlmL(display_short)	psi-mi:usf2_human(display_long)|uniprotkb:USF2(gene name)|psi-mi:USF2(display_short)|uniprotkb:FOS-interacting protein(gene name synonym)|uniprotkb:Upstream transcription factor 2(gene name synonym)|uniprotkb:Major late transcription factor 2(gene name synonym)|uniprotkb:BHLHB12(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 12(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850838|imex:IM-13779-5502	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR000241(Putative RNA methylase)|interpro:IPR017244(S-adenosyl-L-dependent RNA methyltransferase, bacteria, predicted)|interpro:IPR019614|interpro:IPR004114(THUMP)|interpro:IPR029063|refseq:WP_002211293.1|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008990""(""rRNA (guanine-N2-)-methyltransferase activity"")|go:""GO:0052915""(""23S rRNA (guanine(2445)-N(2))-methyltransferase activity"")|go:""GO:0070043""(""rRNA (guanine-N7-)-methyltransferase activity"")|interpro:IPR053943|interpro:IPR054170|refseq:YP_002346441.1|panther:PTHR47313(orthology-group)"	"refseq:NP_003358.1|refseq:NP_997174.1|ensembl:ENSG00000105698.16(gene)|ensembl:ENST00000222305.8(transcript)|go:""GO:0000430""(regulation of transcription from RNA polymerase II promoter by glucose)|go:""GO:0000432""(positive regulation of transcription from RNA polymerase II promoter by glucose)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007595""(lactation)|go:""GO:0010255""(glucose mediated signaling pathway)|go:""GO:0019086""(late viral transcription)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR051732|mint:Q15853|rcsb pdb:8IA3|reactome:R-HSA-9018519|refseq:NP_001308079.1|panther:PTHR46117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:iHm4lVChjpFLlur5QYorXnBhS98632	rogid:lEFfsCJcH99GmZndMiaVI3I4EaA9606	intact-crc:0C106B31C5165A7C|rigid:7W/En9v/wNN41EUsSC9h9c1kZEY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15853	uniprotkb:A0A2S9PJE2	intact:EBI-1055994|uniprotkb:Q15851|uniprotkb:Q15852|uniprotkb:O00671|uniprotkb:O00709|uniprotkb:Q05750|uniprotkb:Q07952|uniprotkb:Q6FI33|ensembl:ENSP00000222305.2|uniprotkb:Q6YI47	intact:EBI-2850829|uniprotkb:Q74WU5|uniprotkb:Q0WC89|uniprotkb:Q7CK47|uniprotkb:A0A384L2F1	psi-mi:usf2_human(display_long)|uniprotkb:USF2(gene name)|psi-mi:USF2(display_short)|uniprotkb:FOS-interacting protein(gene name synonym)|uniprotkb:Upstream transcription factor 2(gene name synonym)|uniprotkb:Major late transcription factor 2(gene name synonym)|uniprotkb:BHLHB12(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 12(gene name synonym)	psi-mi:a0a2s9pje2_yerpe(display_long)|uniprotkb:ahpC(gene name)|psi-mi:ahpC(display_short)|uniprotkb:YPO3194(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850826|imex:IM-13779-5499	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003358.1|refseq:NP_997174.1|ensembl:ENSG00000105698.16(gene)|ensembl:ENST00000222305.8(transcript)|go:""GO:0000430""(regulation of transcription from RNA polymerase II promoter by glucose)|go:""GO:0000432""(positive regulation of transcription from RNA polymerase II promoter by glucose)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007595""(lactation)|go:""GO:0010255""(glucose mediated signaling pathway)|go:""GO:0019086""(late viral transcription)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043425""(bHLH transcription factor binding)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0055088""(lipid homeostasis)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:1990837""(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR051732|mint:Q15853|rcsb pdb:8IA3|reactome:R-HSA-9018519|refseq:NP_001308079.1|panther:PTHR46117(orthology-group)"	"interpro:IPR013766(Thioredoxin domain)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|refseq:WP_002208675.1|go:""GO:0005829""(cytosol)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0008379""(thioredoxin peroxidase activity)|go:""GO:0042744""(hydrogen peroxide catabolic process)|go:""GO:0045454""(cell redox homeostasis)|interpro:IPR036249|refseq:YP_002348099.1|interpro:IPR050217|panther:PTHR10681(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lEFfsCJcH99GmZndMiaVI3I4EaA9606	rogid:GnZEc/ZzTTpq4nrPnH46z4CNIwg632	intact-crc:73F5BBED594F58E9|rigid:WsSlH9alwKZcr6Xm/rBaZAdm0rw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0W9W3	uniprotkb:Q16831	intact:EBI-2850864|uniprotkb:Q74PD6|uniprotkb:A0A0H2W8D7|uniprotkb:A0A380PJZ2|uniprotkb:Q7CFP7|uniprotkb:A0A384K9N9	intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032.4|ensembl:ENSP00000378931.4	psi-mi:q0w9w3_yerpe(display_long)|uniprotkb:mtlA(gene name)|psi-mi:mtlA(display_short)|uniprotkb:EIICBA-Mtl(gene name synonym)|uniprotkb:YPO4068(locus name)	psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850869|imex:IM-13779-5504	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013011(Phosphotransferase system, EIIB component, type 2)|interpro:IPR013014(Phosphotransferase system, EIIC component, type 2)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|interpro:IPR003501(Phosphotransferase system, lactose/cellobiose-specific IIB subunit)|interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR004718(Phosphotransferase system, mannitol-specific enzyme IIC)|interpro:IPR029503|refseq:WP_002209621.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0022872""(""protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity"")|interpro:IPR036095|refseq:YP_002348925.1|interpro:IPR050893"	"refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696.14(gene)|ensembl:ENST00000331803.8(transcript)|ensembl:ENST00000395564.9(transcript)|go:""GO:0004850""(uridine phosphorylase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|go:""GO:0006218""(uridine catabolic process)|go:""GO:0006248""(CMP catabolic process)|go:""GO:0006249""(dCMP catabolic process)|go:""GO:0009032""(thymidine phosphorylase activity)|go:""GO:0042149""(cellular response to glucose starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0044206""(UMP salvage)|go:""GO:0046050""(UMP catabolic process)|go:""GO:0046074""(dTMP catabolic process)|go:""GO:0046079""(dUMP catabolic process)|go:""GO:0047847""(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|mint:Q16831|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621|panther:PTHR43691(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IRMdiu3ZdRcaOFT1CtHmg2fPok8632	rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606	intact-crc:906518F3B70B438E|rigid:GYhMs1C3I1bnbIZyJcs2BlD7mFA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAF0	uniprotkb:A0JNW5	intact:EBI-2850915|uniprotkb:Q0WAF3	intact:EBI-2850901|uniprotkb:Q8NDL1|uniprotkb:O75183|uniprotkb:Q9BTS5|uniprotkb:Q9H0F1|uniprotkb:A0PJE5|uniprotkb:Q96C30|ensembl:ENSP00000279907.7	"psi-mi:wecf_yerpe(display_long)|uniprotkb:rffT(gene name synonym)|uniprotkb:""TDP-Fuc4NAc:lipid II Fuc4NAc transferase""(gene name synonym)|uniprotkb:YPO3857(locus name)|uniprotkb:y0371(locus name)|uniprotkb:YP_3188(locus name)|uniprotkb:wecF(gene name)|psi-mi:wecF(display_short)|uniprotkb:4-alpha-L-fucosyltransferase(gene name synonym)"	psi-mi:blt3b_human(display_long)|uniprotkb:BLTP3B(gene name)|psi-mi:BLTP3B(display_short)|uniprotkb:KIAA0701(gene name synonym)|uniprotkb:SHIP164(gene name synonym)|uniprotkb:Syntaxin-6 Habc-interacting protein of 164 kDa(gene name synonym)|uniprotkb:UHRF1-binding protein 1-like(gene name synonym)|uniprotkb:UHRF1BP1L(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850912|imex:IM-13779-5506	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR009993(4-alpha-L-fucosyltransferase)|go:""GO:0005886""(plasma membrane)|go:""GO:0008417""(fucosyltransferase activity)|go:""GO:0009246""(enterobacterial common antigen biosynthetic process)|go:""GO:0036065""(fucosylation)|go:""GO:0102031""(4-acetamido-4,6-dideoxy-D-galactose transferase activity)|refseq:WP_002211979.1|refseq:YP_002348735.1"	"refseq:NP_001006948.1|refseq:NP_055869.1|ensembl:ENSG00000111647.13(gene)|ensembl:ENST00000279907.12(transcript)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0034498""(early endosome to Golgi transport)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0062069""(GARP complex binding)|go:""GO:0120009""(intermembrane lipid transfer)|go:""GO:0120013""(lipid transfer activity)|interpro:IPR026728|interpro:IPR026854|mint:A0JNW5|reactome:R-HSA-9696270|panther:PTHR22774(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:fmIbBWAFNDygowtZlQ2RENpuJ20632	rogid:237hjaOv2LiPUuNRvDZ3pPMym1Q9606	intact-crc:215C3996540A0BDB|rigid:Dsfm1NIK7yOrPVXagvwdC9svDeU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZAR3	uniprotkb:Q9UH99	intact:EBI-2850881|uniprotkb:Q0WAT0|uniprotkb:Q8D1H0	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|uniprotkb:B0QY62|uniprotkb:Q504T5|ensembl:ENSP00000383992.1|ensembl:ENSP00000385740.1|ensembl:ENSP00000508608.1	psi-mi:pur9_yerpe(display_long)|uniprotkb:YPO3728(locus name)|uniprotkb:y0502(locus name)|uniprotkb:YP_3091(locus name)|uniprotkb:purH(gene name)|psi-mi:purH(display_short)	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850887|imex:IM-13779-5507	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR024051|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR011607(MGS-like)|go:""GO:0003937""(IMP cyclohydrolase activity)|go:""GO:0004643""(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006189""('de novo' IMP biosynthetic process)|interpro:IPR036914|refseq:WP_002210692.1|refseq:YP_002348608.1|panther:PTHR11692(orthology-group)"	"refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|ensembl:ENSG00000100242.16(gene)|ensembl:ENST00000405510.5(transcript)|ensembl:ENST00000406622.5(transcript)|ensembl:ENST00000689035.1(transcript)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0000794""(condensed nuclear chromosome)|go:""GO:0005521""(lamin binding)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005637""(nuclear inner membrane)|go:""GO:0007052""(mitotic spindle organization)|go:""GO:0007097""(nuclear migration)|go:""GO:0008017""(microtubule binding)|go:""GO:0010008""(endosome membrane)|go:""GO:0021817""(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0031022""(nuclear migration along microfilament)|go:""GO:0031965""(nuclear membrane)|go:""GO:0034993""(meiotic nuclear membrane microtubule tethering complex)|go:""GO:0042802""(identical protein binding)|go:""GO:0043495""(protein-membrane adaptor activity)|go:""GO:0051321""(meiotic cell cycle)|go:""GO:0051642""(centrosome localization)|go:""GO:0090292""(nuclear matrix anchoring at nuclear membrane)|go:""GO:0140444""(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR040994|interpro:IPR045119|mint:Q9UH99|rcsb pdb:3UNP|rcsb pdb:4DXR|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|panther:PTHR12911(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Q4MQE1I5c7hhzZ15sabLqYY2+7c632	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	intact-crc:01574F4749AE6FD1|rigid:EQZca1xrhledOreju1ZgU/qLZRw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P30530	uniprotkb:A0A5P8YJ66	intact:EBI-2850927|uniprotkb:Q9UD27|uniprotkb:Q8N5L2|ensembl:ENSP00000301178.3	intact:EBI-2850046|uniprotkb:Q74RM6|uniprotkb:A0A2U2H1F0|uniprotkb:A0A0H2W677|uniprotkb:Q7CGI7|uniprotkb:A0A384KU41	psi-mi:ufo_human(display_long)|uniprotkb:UFO(gene name synonym)|uniprotkb:AXL oncogene(gene name synonym)|uniprotkb:AXL(gene name)|psi-mi:AXL(display_short)	psi-mi:a0a5p8yj66_yerpe(display_long)|uniprotkb:YPO0684(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850924|imex:IM-13779-5508	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001690.2|refseq:NP_068713.2|ensembl:ENSG00000167601.12(gene)|ensembl:ENST00000301178.9(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0001764""(neuron migration)|go:""GO:0001779""(natural killer cell differentiation)|go:""GO:0001786""(phosphatidylserine binding)|go:""GO:0001961""(positive regulation of cytokine-mediated signaling pathway)|go:""GO:0001974""(blood vessel remodeling)|go:""GO:0004713""(protein tyrosine kinase activity)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006909""(phagocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0007165""(signal transduction)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007283""(spermatogenesis)|go:""GO:0007399""(nervous system development)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009986""(cell surface)|go:""GO:0010936""(negative regulation of macrophage cytokine production)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016477""(cell migration)|go:""GO:0021885""(forebrain cell migration)|go:""GO:0030168""(platelet activation)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0032036""(myosin heavy chain binding)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032825""(positive regulation of natural killer cell differentiation)|go:""GO:0032940""(secretion by cell)|go:""GO:0034101""(erythrocyte homeostasis)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0035457""(cellular response to interferon-alpha)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0042698""(ovulation cycle)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043235""(receptor complex)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0043548""(phosphatidylinositol 3-kinase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0046718""(symbiont entry into host cell)|go:""GO:0048010""(vascular endothelial growth factor receptor signaling pathway)|go:""GO:0048469""(cell maturation)|go:""GO:0048549""(positive regulation of pinocytosis)|go:""GO:0048678""(response to axon injury)|go:""GO:0051250""(negative regulation of lymphocyte activation)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060068""(vagina development)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0097028""(dendritic cell differentiation)|go:""GO:0097350""(neutrophil clearance)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1903902""(positive regulation of viral life cycle)|go:""GO:2000669""(negative regulation of dendritic cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036179|interpro:IPR050122|mint:P30530|rcsb pdb:2C5D|rcsb pdb:4RA0|rcsb pdb:5U6B|rcsb pdb:5VXZ|reactome:R-HSA-4420097|panther:PTHR24416(orthology-group)|ensembl:ENSP00000301178.3|ensembl:ENST00000359092.7|ensembl:ENSP00000351995.2"	refseq:WP_002212169.1|interpro:IPR036465|refseq:YP_002345750.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:GMGuoyV5CkwYx9zsEx4NTCkPezA9606	rogid:KizmEigIJwb1SmlvV0RiTRhkoTQ632	intact-crc:A538D2E61C2012C3|rigid:t8Thdi2mhxbuMpmFylT0UpqdX9o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D194	uniprotkb:O75385	intact:EBI-2847851|uniprotkb:Q74XR4	intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560.3	psi-mi:q8d194_yerpe(display_long)|uniprotkb:dAK1_1(gene name)|psi-mi:dAK1_1(display_short)|uniprotkb:YP_0337(locus name)|uniprotkb:y0840(locus name)	psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850894|imex:IM-13779-5505	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004006(Dak kinase)|go:""GO:0004371""(glycerone kinase activity)|go:""GO:0006071""(glycerol metabolic process)|interpro:IPR050861"	"refseq:NP_003556.1|ensembl:ENSG00000177169.10(gene)|ensembl:ENST00000321867.6(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0000423""(mitophagy)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0005776""(autophagosome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006914""(autophagy)|go:""GO:0007165""(signal transduction)|go:""GO:0008104""(protein localization)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0016236""(macroautophagy)|go:""GO:0016241""(regulation of macroautophagy)|go:""GO:0018105""(peptidyl-serine phosphorylation)|go:""GO:0030424""(axon)|go:""GO:0031102""(neuron projection regeneration)|go:""GO:0031175""(neuron projection development)|go:""GO:0031267""(small GTPase binding)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031669""(cellular response to nutrient levels)|go:""GO:0033554""(cellular response to stress)|go:""GO:0034045""(phagophore assembly site membrane)|go:""GO:0034727""(piecemeal microautophagy of the nucleus)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0042594""(response to starvation)|go:""GO:0042802""(identical protein binding)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046777""(protein autophosphorylation)|go:""GO:0048671""(negative regulation of collateral sprouting)|go:""GO:0048675""(axon extension)|go:""GO:0051020""(GTPase binding)|go:""GO:0055037""(recycling endosome)|go:""GO:0061709""(reticulophagy)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1903059""(regulation of protein lipidation)|go:""GO:1903349""(omegasome membrane)|go:""GO:1990244""(histone H2AT120 kinase activity)|go:""GO:1990316""(Atg1/ULK1 kinase complex)|go:""GO:2000786""(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|interpro:IPR045269|interpro:IPR048941|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|rcsb pdb:8P5G|rcsb pdb:8P5H|rcsb pdb:8P5I|rcsb pdb:8P5J|rcsb pdb:8P5K|rcsb pdb:8P5L|rcsb pdb:8SOI|rcsb pdb:8SQZ|rcsb pdb:8SRM|rcsb pdb:8SV9|rcsb pdb:9C82|reactome:R-HSA-1632852|reactome:R-HSA-5357905|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|dip:DIP-35196N|ensembl:ENSP00000324560.3|panther:PTHR24348(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:PGSwAYXIFUUnJmzpLaHT1vlvQxc632	rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606	intact-crc:7032748A10054CEF|rigid:WGjj/16rVLSVBxfabAWujL+56u8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B3D9	uniprotkb:Q5T124	intact:EBI-2839898|uniprotkb:Q74TT7|uniprotkb:Q7CIK3|uniprotkb:Q0WER9|uniprotkb:A0A0H2W4Z4	intact:EBI-746004|uniprotkb:Q5T117|uniprotkb:Q5T120|uniprotkb:Q5T125|uniprotkb:Q5T126|uniprotkb:Q5T129|uniprotkb:Q5T131|uniprotkb:Q5T133|uniprotkb:Q63HM6|uniprotkb:Q71RB3|uniprotkb:Q8IY27|uniprotkb:Q8N1L6|uniprotkb:Q8N9M4|uniprotkb:Q8NA18|uniprotkb:Q8NFE3|uniprotkb:Q8NFE4|uniprotkb:Q8NFE6|uniprotkb:D3DPK6|ensembl:ENSP00000363338.3|ensembl:ENSP00000363339.1	psi-mi:a0a3n4b3d9_yerpe(display_long)|uniprotkb:YPO2252(locus name)	psi-mi:ubx11_human(display_long)|uniprotkb:Socius(gene name synonym)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:SOC(gene name synonym)|uniprotkb:PP2243(orf name)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850955|imex:IM-13779-5512	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010132(Type I secretion system ATPase, HlyB)|interpro:IPR005074(Peptidase C39, bacteriocin processing)|interpro:IPR017871|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0030253""(protein secretion by the type I secretion system)|go:""GO:0030256""(type I protein secretion system complex)|go:""GO:0140359""(ABC-type transporter activity)|refseq:WP_002210593.1|interpro:IPR039421|interpro:IPR036640|interpro:IPR039395|refseq:YP_002347219.1"	"refseq:NP_001070730.1|refseq:NP_663320.2|refseq:NP_892120.2|ensembl:ENSG00000158062.21(gene)|ensembl:ENST00000374221.7(transcript)|ensembl:ENST00000374222.6(transcript)|go:""GO:0005829""(cytosol)|go:""GO:0005856""(cytoskeleton)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001012(UBX)|interpro:IPR012989(SEP)|interpro:IPR029071|interpro:IPR036241|mint:Q5T124|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|panther:PTHR23333(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zoNmjmcwVuJTJdvHLHxWk7xECDQ632	rogid:sTWknIh+W0jcWm0/2rZ0ZIG4zUs9606	intact-crc:BE21E90DC28E5DA1|rigid:lbi3Nq7KYMkC2Y5sI0dzVZZQPNg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NWZ5	uniprotkb:Q8ZA84	intact:EBI-2466660|uniprotkb:Q9H3Z2|uniprotkb:Q8N524|uniprotkb:Q70AQ5|uniprotkb:Q5JWV0|uniprotkb:B7Z8N2|ensembl:ENSP00000346155.6	intact:EBI-2842602|uniprotkb:Q0WA86	psi-mi:uckl1_human(display_long)|uniprotkb:F538(orf name)|uniprotkb:UCKL1(gene name)|psi-mi:UCKL1(display_short)|uniprotkb:URKL1(gene name synonym)	psi-mi:capp_yerpe(display_long)|uniprotkb:ppc(gene name)|psi-mi:ppc(display_short)|uniprotkb:YPO3929(locus name)|uniprotkb:y0308(locus name)|uniprotkb:YP_3121(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850948|imex:IM-13779-5509	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060329.2|refseq:NP_001180308.1|ensembl:ENSG00000198276.16(gene)|ensembl:ENST00000354216.11(transcript)|go:""GO:0004849""(uridine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0043097""(pyrimidine nucleoside salvage)|go:""GO:0043771""(cytidine kinase activity)|go:""GO:0044206""(UMP salvage)|go:""GO:0044211""(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029057|mint:Q9NWZ5|reactome:R-HSA-73614|panther:PTHR10285(orthology-group)"	"interpro:IPR033129|interpro:IPR021135|interpro:IPR018129|interpro:IPR022805|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005829""(cytosol)|go:""GO:0006099""(tricarboxylic acid cycle)|go:""GO:0006107""(oxaloacetate metabolic process)|go:""GO:0008964""(phosphoenolpyruvate carboxylase activity)|go:""GO:0015977""(carbon fixation)|refseq:WP_002209491.1|refseq:YP_002348802.1|panther:PTHR30523(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FkKO/bZUZfOV2Fe8iGuOzC+Stpg9606	rogid:aPbGF+uF/gTYbtmc4Mkr1Ys0jNc632	intact-crc:217B0EABB7D7DC53|rigid:JOYoYdlpbu0yc2ExbnEYqh32dzE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q70EK8	uniprotkb:Q8CZX0	intact:EBI-742050|uniprotkb:Q68DA5|uniprotkb:Q8WVQ5|uniprotkb:Q9P2J7|intact:EBI-28968860|ensembl:ENSP00000409906.1|ensembl:ENSP00000509606.1	intact:EBI-2843256	psi-mi:ubp53_human(display_long)|uniprotkb:Inactive ubiquitin-specific peptidase 53(gene name synonym)|uniprotkb:USP53(gene name)|psi-mi:USP53(display_short)|uniprotkb:KIAA1350(gene name synonym)	psi-mi:q8czx0_yerpe(display_long)|uniprotkb:y3221(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850962|imex:IM-13779-5510	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_061923.2|refseq:XP_011530339.1|refseq:XP_005263130.1|refseq:XP_016863801.1|refseq:XP_016863802.1|refseq:XP_016863803.1|refseq:XP_016863804.1|ensembl:ENSG00000145390.12(gene)|ensembl:ENST00000450251.6(transcript)|ensembl:ENST00000692078.1(transcript)|go:""GO:0001508""(action potential)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007605""(sensory perception of sound)|go:""GO:0010996""(response to auditory stimulus)|go:""GO:0016579""(protein deubiquitination)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1905584""(outer hair cell apoptotic process)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|interpro:IPR038765|interpro:IPR052398|panther:PTHR22975(orthology-group)"	"interpro:IPR004704(Phosphotransferase system, mannose/fructose/sorbose family IID component)|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|interpro:IPR050303"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:h3IUmdG6ippu/JhmPQiMHLhni7I9606	rogid:qJG/9uPdua0KpEAcJ9dXeyS7Cww632	intact-crc:10357F4D2C567207|rigid:lzpvok6Pf5N9xA3OZrJ5/9vZ23A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BYM8	uniprotkb:A0A2U2GXH7	intact:EBI-2340624|uniprotkb:O95623|uniprotkb:Q9BYM9|uniprotkb:Q96BS3|uniprotkb:Q86SL2|ensembl:ENSP00000348632.6	intact:EBI-2848470|uniprotkb:Q74WH6|uniprotkb:Q0WHG3|uniprotkb:A0A0H2W2J4|uniprotkb:Q7CHB5|uniprotkb:A0A384K9G2	psi-mi:hoil1_human(display_long)|uniprotkb:RBCK1(gene name)|psi-mi:RBCK1(display_short)|uniprotkb:C20orf18(gene name synonym)|uniprotkb:RNF54(gene name synonym)|uniprotkb:UBCE7IP3(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 3(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein 4(gene name synonym)|uniprotkb:HBV-associated factor 4(gene name synonym)|uniprotkb:RING finger protein 54(gene name synonym)|uniprotkb:Heme-oxidized IRP2 ubiquitin ligase 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HOIL-1(gene name synonym)	psi-mi:a0a2u2gxh7_yerpe(display_long)|uniprotkb:YPO1246(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850969|imex:IM-13779-5511	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-47737N|ensembl:ENSG00000125826.22(gene)|ensembl:ENST00000356286.10(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005829""(cytosol)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0050852""(T cell receptor signaling pathway)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051220""(obsolete cytoplasmic sequestering of protein)|go:""GO:0060546""(negative regulation of necroptotic process)|go:""GO:0071797""(LUBAC complex)|go:""GO:0097039""(protein linear polyubiquitination)|go:""GO:0140311""(protein sequestering activity)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1990757""(ubiquitin ligase activator activity)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000626(Ubiquitin)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR029071|interpro:IPR036443|interpro:IPR044066|interpro:IPR047557|interpro:IPR047558|interpro:IPR047559|interpro:IPR051628|mint:Q9BYM8|rcsb pdb:2CRC|rcsb pdb:2LGY|rcsb pdb:4DBG|rcsb pdb:7V8E|rcsb pdb:7YUI|rcsb pdb:7YUJ|rcsb pdb:8BVL|rcsb pdb:8EAZ|rcsb pdb:8K6Q|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-983168|refseq:NP_006453.1|refseq:NP_112506.2|efo:""Orphanet:329173""|efo:""Orphanet:397937""|panther:PTHR22770(orthology-group)"	interpro:IPR009826(DNA circulation, N-terminal)|refseq:WP_002208852.1|refseq:YP_002346275.1|interpro:IPR052399	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:TrkfR++u4X4c/KzUlC5Mcu6SgVs9606	rogid:Qbi9eC3jfsnnPhDaTUvn+57rY7s632	intact-crc:225B714009B55870|rigid:9kYtLe/OROMJrT6ZVznGKlXkENU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5KZU3	uniprotkb:Q9NWZ5	intact:EBI-2850940	intact:EBI-2466660|uniprotkb:Q9H3Z2|uniprotkb:Q8N524|uniprotkb:Q70AQ5|uniprotkb:Q5JWV0|uniprotkb:B7Z8N2|ensembl:ENSP00000346155.6	psi-mi:a0a3g5kzu3_yerpe(display_long)|uniprotkb:y0245(locus name)|uniprotkb:ssuA(gene name)|psi-mi:ssuA(display_short)	psi-mi:uckl1_human(display_long)|uniprotkb:F538(orf name)|uniprotkb:UCKL1(gene name)|psi-mi:UCKL1(display_short)|uniprotkb:URKL1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850937|imex:IM-13779-5513	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|interpro:IPR010067(ABC transporter, substrate-binding protein, aliphatic sulphonates)|interpro:IPR015168(NMT1/THI5 like)|uniprotkb:A0A6B3T643(uniprot-removed-ac)|go:""GO:0016020""(membrane)|go:""GO:0042597""(periplasmic space)|go:""GO:0042626""(ATPase-coupled transmembrane transporter activity)|refseq:WP_002220949.1"	"refseq:NP_060329.2|refseq:NP_001180308.1|ensembl:ENSG00000198276.16(gene)|ensembl:ENST00000354216.11(transcript)|go:""GO:0004849""(uridine kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0043097""(pyrimidine nucleoside salvage)|go:""GO:0043771""(cytidine kinase activity)|go:""GO:0044206""(UMP salvage)|go:""GO:0044211""(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029057|mint:Q9NWZ5|reactome:R-HSA-73614|panther:PTHR10285(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:kuMqjHfkYUIBJ4hy+1j+bwqjjo4632	rogid:FkKO/bZUZfOV2Fe8iGuOzC+Stpg9606	intact-crc:AEB18695A0592BF5|rigid:pijiiF2rrqNKp1S05yKJU0sAhJQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZM8	uniprotkb:Q15029	intact:EBI-2848309	intact:EBI-357897|uniprotkb:Q9BUR0|ensembl:ENSP00000392094.1|ensembl:ENSP00000467805.1|uniprotkb:D3DX58|uniprotkb:B4DK30|uniprotkb:B4DMC0|uniprotkb:K7EJ81	psi-mi:q8czm8_yerpe(display_long)|uniprotkb:ptsA(gene name)|psi-mi:ptsA(display_short)|uniprotkb:y3776(locus name)	psi-mi:u5s1_human(display_long)|uniprotkb:EFTUD2(gene name)|psi-mi:EFTUD2(display_short)|uniprotkb:KIAA0031(gene name synonym)|uniprotkb:SNRP116(gene name synonym)|uniprotkb:U5 snRNP-specific protein, 116 kDa(gene name synonym)|uniprotkb:Elongation factor Tu GTP-binding domain-containing protein 2(gene name synonym)|uniprotkb:SNU114 homolog(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850987|imex:IM-13779-5517	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR018274|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR023151|interpro:IPR006318(Phosphoenolpyruvate-protein phosphotransferase)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR008731(Phosphotransferase system, PEP-utilising enzyme, N-terminal)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|go:""GO:0005737""(cytoplasm)|go:""GO:0008965""(phosphoenolpyruvate-protein phosphotransferase activity)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR040442|interpro:IPR035895|interpro:IPR036618|interpro:IPR036637|interpro:IPR050499"	"ensembl:ENSG00000108883.13(gene)|ensembl:ENST00000426333.7(transcript)|ensembl:ENST00000591382.5(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0015030""(Cajal body)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0030623""(U5 snRNA binding)|go:""GO:0042220""(response to cocaine)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071007""(U2-type catalytic step 2 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0071466""(cellular response to xenobiotic stimulus)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR041095|interpro:IPR044121|mint:Q15029|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|rcsb pdb:7QTT|rcsb pdb:7W59|rcsb pdb:7W5A|rcsb pdb:7W5B|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0U|rcsb pdb:8I0V|rcsb pdb:8I0W|rcsb pdb:8Q7N|rcsb pdb:8Q7Q|rcsb pdb:8Q7V|rcsb pdb:8Q7W|rcsb pdb:8Q7X|rcsb pdb:8Q91|rcsb pdb:8QO9|rcsb pdb:8QOZ|rcsb pdb:8QP8|rcsb pdb:8QP9|rcsb pdb:8QPA|rcsb pdb:8QPB|rcsb pdb:8QPE|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RC0|rcsb pdb:8RM5|rcsb pdb:8RO2|rcsb pdb:8Y6O|rcsb pdb:9FMD|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_001136077.1|refseq:NP_001245282.1|refseq:NP_001245283.1|refseq:NP_004238.3|efo:""Orphanet:79113""|panther:PTHR42908(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:yFrXLYA0rYHKZA16/O8hjY0IDfU632	rogid:/dBQ7TFnGr31AYrb5e215eQ4vfc9606	intact-crc:57A051404874E802|rigid:1utHoZflz8SEvx8EoW5jDamn9BY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NV66	uniprotkb:A0A0H2W9S4	intact:EBI-2851008|uniprotkb:Q8IVS7|uniprotkb:Q75MN3|uniprotkb:Q9H9C4|uniprotkb:Q75MG8|uniprotkb:Q86V12|uniprotkb:Q6PJG8|ensembl:ENSP00000352645.5	intact:EBI-2851018|uniprotkb:Q74PV1|uniprotkb:A0A380PJ36|uniprotkb:Q7CG39|uniprotkb:Q0WJR3	psi-mi:tyw1_human(display_long)|uniprotkb:RSAFD1(gene name synonym)|uniprotkb:Radical S-adenosyl methionine and flavodoxin domain-containing protein 1(gene name synonym)|uniprotkb:tRNA-yW-synthesizing protein(gene name synonym)|uniprotkb:TYW1(gene name)|psi-mi:TYW1(display_short)|uniprotkb:tRNA wybutosine-synthesizing protein 1 homolog(gene name synonym)	psi-mi:a0a0h2w9s4_yerpe(display_long)|uniprotkb:YPO0398(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851005|imex:IM-13779-5516	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060734.2|ensembl:ENSG00000198874.14(gene)|ensembl:ENST00000359626.10(transcript)|go:""GO:0010181""(FMN binding)|go:""GO:0031591""(wybutosine biosynthetic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0102521""(tRNA-4-demethylwyosine synthase activity)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR007197(Radical SAM)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR013917(Wyosine base formation)|interpro:IPR029039|interpro:IPR034556|reactome:R-HSA-6782861|panther:PTHR13930(orthology-group)"	"interpro:IPR001915(Peptidase M48, Ste24p)|refseq:WP_002209176.1|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0006508""(proteolysis)|refseq:YP_002345475.1|interpro:IPR051156"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lIchhywGFiXMQuJ3R2iq9/oCFI89606	rogid:hu7ik6gGx0jCcFmvYlH72f4i/p4632	intact-crc:6ED111F2F320B4D6|rigid:SpZ2QY2aamcmAOxKT1bfTnpDX6Q	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZH37	uniprotkb:O43914	intact:EBI-2851027|uniprotkb:Q0WHX0|uniprotkb:Q7CH28|uniprotkb:Q74S62	intact:EBI-2214794|ensembl:ENSP00000262629.3|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389	psi-mi:gmhbb_yerpe(display_long)|uniprotkb:gmhB(gene name)|psi-mi:gmhB(display_short)|uniprotkb:D,D-heptose 1,7-bisphosphate phosphatase(gene name synonym)|uniprotkb:YPO1074(locus name)|uniprotkb:YP_2775(locus name)|uniprotkb:y3103(locus name)	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851034|imex:IM-13779-5518	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023214|interpro:IPR006549(HAD-superfamily hydrolase, subfamily IIIA)|interpro:IPR004446(Histidinol phosphatase-related protein)|interpro:IPR006543(Histidinol-phosphate phosphatase)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009244""(lipopolysaccharide core region biosynthetic process)|go:""GO:0034200""(D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity)|go:""GO:0097171""(ADP-L-glycero-beta-D-manno-heptose biosynthetic process)|interpro:IPR036412|refseq:WP_002220062.1|refseq:YP_002346118.1|panther:PTHR42891(orthology-group)"	"ensembl:ENSG00000011600.12(gene)|ensembl:ENST00000262629.9(transcript)|go:""GO:0002222""(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002274""(myeloid leukocyte activation)|go:""GO:0002282""(microglial cell activation involved in immune response)|go:""GO:0002283""(neutrophil activation involved in immune response)|go:""GO:0002291""(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006968""(cellular defense response)|go:""GO:0007165""(signal transduction)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0030900""(forebrain development)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0032693""(negative regulation of interleukin-10 production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0032911""(negative regulation of transforming growth factor beta1 production)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0034241""(positive regulation of macrophage fusion)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0046872""(metal ion binding)|go:""GO:0048678""(response to axon injury)|go:""GO:0050821""(protein stabilization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:1900272""(negative regulation of long-term synaptic potentiation)|go:""GO:1902685""(positive regulation of receptor localization to synapse)|go:""GO:1904151""(positive regulation of microglial cell mediated cytotoxicity)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:2000010""(positive regulation of protein localization to cell surface)|go:""GO:2001206""(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|rcsb pdb:7Q5W|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695|refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|efo:""Orphanet:2770""|panther:PTHR17554(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TQJisFcuEi2sCw0MeU57QEi79XA632	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	intact-crc:4858D3687923192E|rigid:n9EhWwa190P1L88oXDPQb8m6fvg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BQC6	uniprotkb:Q13838	intact:EBI-2850976|uniprotkb:A0A5P8YFI0|uniprotkb:Q0WFB1|uniprotkb:Q7CIB4	intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000.2|ensembl:ENSP00000379475.1|ensembl:ENSP00000383151.1|ensembl:ENSP00000383152.1|ensembl:ENSP00000387994.1|ensembl:ENSP00000388880.1|ensembl:ENSP00000390999.1|ensembl:ENSP00000391463.1|ensembl:ENSP00000393712.1|ensembl:ENSP00000394160.1|ensembl:ENSP00000398775.1|ensembl:ENSP00000399030.1|ensembl:ENSP00000400326.1|ensembl:ENSP00000404695.1|ensembl:ENSP00000405560.1|ensembl:ENSP00000407419.1|ensembl:ENSP00000411136.1|ensembl:ENSP00000411853.1|ensembl:ENSP00000416269.1	psi-mi:a0a3n4bqc6_yerpe(display_long)|uniprotkb:YPO2045(locus name)	psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850980|imex:IM-13779-5514	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008638(Filamentous haemagglutinin, N-terminal, bacterial)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR025157|refseq:WP_002227945.1|go:""GO:0003824""(catalytic activity)|refseq:YP_002347027.1"	"refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563.14(gene)|ensembl:ENSG00000215425.11(gene)|ensembl:ENSG00000225073.10(gene)|ensembl:ENSG00000225859.10(gene)|ensembl:ENSG00000229496.10(gene)|ensembl:ENSG00000230624.10(gene)|ensembl:ENSG00000235439.10(gene)|ensembl:ENST00000383508.6(transcript)|ensembl:ENST00000396172.6(transcript)|ensembl:ENST00000400295.5(transcript)|ensembl:ENST00000400296.5(transcript)|ensembl:ENST00000412106.5(transcript)|ensembl:ENST00000412330.5(transcript)|ensembl:ENST00000413678.5(transcript)|ensembl:ENST00000414440.5(transcript)|ensembl:ENST00000415689.5(transcript)|ensembl:ENST00000416863.5(transcript)|ensembl:ENST00000430784.5(transcript)|ensembl:ENST00000431360.5(transcript)|ensembl:ENST00000441425.5(transcript)|ensembl:ENST00000445218.5(transcript)|ensembl:ENST00000448296.5(transcript)|ensembl:ENST00000453138.5(transcript)|ensembl:ENST00000456476.5(transcript)|ensembl:ENST00000456666.5(transcript)|ensembl:ENST00000458640.5(transcript)|go:""GO:0000245""(spliceosomal complex assembly)|go:""GO:0000346""(transcription export complex)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0003729""(mRNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005687""(U4 snRNP)|go:""GO:0005688""(U6 snRNP)|go:""GO:0005737""(cytoplasm)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0008380""(RNA splicing)|go:""GO:0010501""(obsolete RNA secondary structure unwinding)|go:""GO:0016607""(nuclear speck)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0017070""(U6 snRNA binding)|go:""GO:0030621""(U4 snRNA binding)|go:""GO:0042802""(identical protein binding)|go:""GO:0043008""(ATP-dependent protein binding)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|rcsb pdb:7ZNK|rcsb pdb:7ZNL|rcsb pdb:8ENK|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418|panther:PTHR47958(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NkWr5G6jpPlJF/AsfmosHqY3b2Q632	rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606	intact-crc:5587723DBEDE349C|rigid:PiLqcq2IQdo35YDbwykmUvOeDn8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1A4	uniprotkb:O75643	intact:EBI-2850994	intact:EBI-1045395|uniprotkb:O94884|uniprotkb:Q6PX59|uniprotkb:Q8NBE6|uniprotkb:Q96IF2|uniprotkb:Q9H7S0|uniprotkb:Q6NZY0|intact:EBI-1051631|ensembl:ENSP00000317123.5	psi-mi:q8d1a4_yerpe(display_long)|uniprotkb:y0798(locus name)|uniprotkb:fhuB(gene name)|psi-mi:fhuB(display_short)	psi-mi:u520_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short)|uniprotkb:HELIC2(gene name synonym)|uniprotkb:KIAA0788(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)|uniprotkb:Activating signal cointegrator 1 complex subunit 3-like 1(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:ASCC3L1(gene name synonym)|uniprotkb:BRR2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2850998|imex:IM-13779-5515	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000522(Bacterial transport system permease protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR037294"	"efo:""Orphanet:791""|dip:DIP-31659N|ensembl:ENSG00000144028.15(gene)|ensembl:ENST00000323853.10(transcript)|go:""GO:0000354""(cis assembly of pre-catalytic spliceosome)|go:""GO:0000388""(""spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)"")|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003689""(DNA clamp loader activity)|go:""GO:0003723""(RNA binding)|go:""GO:0003724""(RNA helicase activity)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005682""(U5 snRNP)|go:""GO:0016020""(membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0046540""(U4/U6 x U5 tri-snRNP complex)|go:""GO:0061775""(cohesin loader activity)|go:""GO:0071005""(U2-type precatalytic spliceosome)|go:""GO:0071006""(U2-type catalytic step 1 spliceosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:0140584""(chromatin extrusion motor activity)|go:""GO:0140665""(ATP-dependent H3-H4 histone complex chaperone activity)|go:""GO:0140849""(ATP-dependent H2AZ histone chaperone activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|interpro:IPR048863|interpro:IPR050474|mint:O75643|rcsb pdb:2Q0Z|rcsb pdb:3JCR|rcsb pdb:4F91|rcsb pdb:4F92|rcsb pdb:4F93|rcsb pdb:4KIT|rcsb pdb:5O9Z|rcsb pdb:5URJ|rcsb pdb:5URK|rcsb pdb:5URM|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8O|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|rcsb pdb:7OS1|rcsb pdb:7OS2|rcsb pdb:7PX3|rcsb pdb:7W5B|rcsb pdb:8BC8|rcsb pdb:8BC9|rcsb pdb:8BCA|rcsb pdb:8BCB|rcsb pdb:8BCC|rcsb pdb:8BCD|rcsb pdb:8BCE|rcsb pdb:8BCF|rcsb pdb:8BCG|rcsb pdb:8BCH|rcsb pdb:8C6J|rcsb pdb:8CH6|rcsb pdb:8H6E|rcsb pdb:8H6J|rcsb pdb:8H6K|rcsb pdb:8H6L|rcsb pdb:8I0P|rcsb pdb:8I0R|rcsb pdb:8I0S|rcsb pdb:8I0T|rcsb pdb:8I0W|rcsb pdb:8Q7Q|rcsb pdb:8Q7V|rcsb pdb:8Q7W|rcsb pdb:8Q7X|rcsb pdb:8Q91|rcsb pdb:8QO9|rcsb pdb:8QOZ|rcsb pdb:8QP9|rcsb pdb:8QPA|rcsb pdb:8QPB|rcsb pdb:8QPK|rcsb pdb:8QXD|rcsb pdb:8QZS|rcsb pdb:8R08|rcsb pdb:8R09|rcsb pdb:8R0A|rcsb pdb:8R0B|rcsb pdb:8RC0|rcsb pdb:8RM5|rcsb pdb:8Y6O|rcsb pdb:9FMD|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_054733.2|refseq:XP_016859092.1|panther:PTHR24075(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PGAfc4VH09eJJH0aF+uMggT6rQg632	rogid:2ZAcbMfMlk2xWWAiy7MeCL0CHtM9606	intact-crc:CB22C6EF4EA8FFEB|rigid:b6wPi544NEUBlWexe6nHhKsvyLI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CWI1	uniprotkb:Q9H3M7	intact:EBI-2845294	intact:EBI-1369170|uniprotkb:B4E3D3|uniprotkb:Q16226|uniprotkb:Q6PML0|uniprotkb:Q9BXG9|ensembl:ENSP00000462521.1	psi-mi:q8cwi1_yerpe(display_long)|uniprotkb:glpC(gene name)|psi-mi:glpC(display_short)|uniprotkb:y0406(locus name)	psi-mi:txnip_human(display_long)|uniprotkb:TXNIP(gene name)|psi-mi:TXNIP(display_short)|uniprotkb:VDUP1(gene name synonym)|uniprotkb:Vitamin D3 up-regulated protein 1(gene name synonym)|uniprotkb:Thioredoxin-binding protein 2(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851048|imex:IM-13779-5519	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR017900|interpro:IPR004017(Cysteine-rich region, CCG)|interpro:IPR017753(Anaerobic glycerol-3-phosphate dehydrogenase, C subunit)|interpro:IPR009051(Alpha-helical ferredoxin)|go:""GO:0009061""(anaerobic respiration)|go:""GO:0009331""(""glycerol-3-phosphate dehydrogenase (FAD) complex"")|go:""GO:0016020""(membrane)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)"	"refseq:NP_006463.3|refseq:NP_001300901.1|ensembl:ENSG00000265972.6(gene)|ensembl:ENST00000582401.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006954""(inflammatory response)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009612""(response to mechanical stimulus)|go:""GO:0009749""(response to glucose)|go:""GO:0015031""(protein transport)|go:""GO:0030216""(keratinocyte differentiation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032355""(response to estradiol)|go:""GO:0032570""(response to progesterone)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042542""(response to hydrogen peroxide)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0048008""(platelet-derived growth factor receptor signaling pathway)|go:""GO:0051592""(response to calcium ion)|go:""GO:0051782""(negative regulation of cell division)|go:""GO:0071228""(cellular response to tumor cell)|go:""GO:0140052""(cellular response to oxidised low-density lipoprotein particle stimulus)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR050357|mint:Q9H3M7|rcsb pdb:4GEI|rcsb pdb:4GEJ|rcsb pdb:4GFX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4ROF|rcsb pdb:4ROJ|rcsb pdb:5CQ2|rcsb pdb:5DF6|rcsb pdb:5DWS|rcsb pdb:5DZD|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826|reactome:R-HSA-9707564|panther:PTHR11188(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/26	rogid:Ni4uunc/ZlYLbmbLclTTzn5OT10632	rogid:jJMKfl1/92UPMTXBLCdu6NcYbjQ9606	intact-crc:CED7E62521017B4F|rigid:3ccUuGqQ8b6bRrEgkOyZ/0R3An4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBZ9	uniprotkb:Q9H3N1	intact:EBI-2851065|uniprotkb:Q0WC55	intact:EBI-1051115|uniprotkb:Q8N487|uniprotkb:Q8NBN5|uniprotkb:Q9Y4T6|uniprotkb:B2R7A4|ensembl:ENSP00000393316.2	psi-mi:dpo4_yerpe(display_long)|uniprotkb:dinP(gene name synonym)|uniprotkb:YPO3231(locus name)|uniprotkb:y0959(locus name)|uniprotkb:YP_0702(locus name)|uniprotkb:dinB(gene name)|psi-mi:dinB(display_short)	psi-mi:tmx1_human(display_long)|uniprotkb:Transmembrane Trx-related protein(gene name synonym)|uniprotkb:TMX1(gene name)|psi-mi:TMX1(display_short)|uniprotkb:TXNDC1(gene name synonym)|uniprotkb:TMX(gene name synonym)|uniprotkb:TXNDC(gene name synonym)|uniprotkb:PSEC0085(orf name)|uniprotkb:UNQ235/PRO268(orf name)|uniprotkb:Thioredoxin domain-containing protein 1(gene name synonym)|uniprotkb:Protein disulfide-isomerase TMX1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851062|imex:IM-13779-5520	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR043502|interpro:IPR017961|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR022880|refseq:WP_002208708.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0003684""(damaged DNA binding)|go:""GO:0003887""(DNA-directed DNA polymerase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006261""(DNA-templated DNA replication)|go:""GO:0009432""(SOS response)|go:""GO:0042276""(error-prone translesion synthesis)|interpro:IPR043128|interpro:IPR036775|interpro:IPR053848|refseq:YP_002348133.1|interpro:IPR050116|panther:PTHR11076(orthology-group)"	"refseq:NP_110382.3|ensembl:ENSG00000139921.13(gene)|ensembl:ENST00000457354.7(transcript)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0004857""(enzyme inhibitor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0010868""(negative regulation of triglyceride biosynthetic process)|go:""GO:0012505""(endomembrane system)|go:""GO:0015035""(protein-disulfide reductase activity)|go:""GO:0015036""(disulfide oxidoreductase activity)|go:""GO:0031966""(mitochondrial membrane)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0044233""(mitochondria-associated endoplasmic reticulum membrane contact site)|go:""GO:0051924""(regulation of calcium ion transport)|go:""GO:0090331""(negative regulation of platelet aggregation)|go:""GO:1904294""(positive regulation of ERAD pathway)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR052454|mint:Q9H3N1|rcsb pdb:1X5E|panther:PTHR46107(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dJC1TxxW9BoCSiFaklVosXbx3KY632	rogid:ZJH5N22Dnrk+SXa3Ysqqfu1md/I9606	intact-crc:5DB26ACC1EF4AB45|rigid:VqkdWheycx0SE9dClqYI9ets87k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BS26	uniprotkb:Q8ZCQ2	intact:EBI-541644|uniprotkb:O60319|uniprotkb:Q5VWZ7|uniprotkb:Q6UW14|uniprotkb:Q8WX67|intact:EBI-1054855|uniprotkb:Q4VXC1|ensembl:ENSP00000262455.6	intact:EBI-2850142|uniprotkb:Q0WCY7	psi-mi:erp44_human(display_long)|uniprotkb:ERP44(gene name)|psi-mi:ERP44(display_short)|uniprotkb:UNQ532/PRO1075(orf name)|uniprotkb:TXNDC4(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 4(gene name synonym)|uniprotkb:KIAA0573(gene name synonym)	psi-mi:pur4_yerpe(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:YPO2921(locus name)|uniprotkb:YP_2536(locus name)|uniprotkb:y1309(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851055|imex:IM-13779-5522	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055866.1|ensembl:ENSG00000023318.9(gene)|ensembl:ENST00000262455.7(transcript)|go:""GO:0003756""(protein disulfide isomerase activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005788""(endoplasmic reticulum lumen)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0006457""(protein folding)|go:""GO:0006986""(response to unfolded protein)|go:""GO:0009100""(glycoprotein metabolic process)|go:""GO:0009986""(cell surface)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0035580""(specific granule lumen)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0070062""(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041862|interpro:IPR041870|interpro:IPR052643|mint:Q9BS26|rcsb pdb:2R2J|rcsb pdb:5GU6|rcsb pdb:5GU7|rcsb pdb:5HQP|rcsb pdb:5XWM|reactome:R-HSA-6798695|panther:PTHR46295(orthology-group)"	"interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR029062|refseq:WP_002211561.1|interpro:IPR040707|go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609|refseq:YP_002347851.1|panther:PTHR10099(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TpwaFRifveb03iRPS2pEZve1kLA9606	rogid:8JTbD5hWDWC5PK7sHtiOwqqdyHs632	intact-crc:9D257C3995AC16C1|rigid:52DlWJKtiKujXGYflQWl1q1usMU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43914	uniprotkb:Q9ZC68	intact:EBI-2214794|ensembl:ENSP00000262629.3|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389	intact:EBI-2843867|uniprotkb:Q7CI72|uniprotkb:Q74UK4	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	psi-mi:astd_yerpe(display_long)|uniprotkb:astD(gene name)|psi-mi:astD(display_short)|uniprotkb:Succinylglutamic semialdehyde dehydrogenase(gene name synonym)|uniprotkb:YPO1964(locus name)|uniprotkb:y2347(locus name)|uniprotkb:YP_1709(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851041|imex:IM-13779-5523	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000011600.12(gene)|ensembl:ENST00000262629.9(transcript)|go:""GO:0002222""(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:""GO:0002223""(stimulatory C-type lectin receptor signaling pathway)|go:""GO:0002274""(myeloid leukocyte activation)|go:""GO:0002282""(microglial cell activation involved in immune response)|go:""GO:0002283""(neutrophil activation involved in immune response)|go:""GO:0002291""(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0006968""(cellular defense response)|go:""GO:0007165""(signal transduction)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0016020""(membrane)|go:""GO:0030036""(actin cytoskeleton organization)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030667""(secretory granule membrane)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0030889""(negative regulation of B cell proliferation)|go:""GO:0030900""(forebrain development)|go:""GO:0032480""(negative regulation of type I interferon production)|go:""GO:0032693""(negative regulation of interleukin-10 production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032816""(positive regulation of natural killer cell activation)|go:""GO:0032911""(negative regulation of transforming growth factor beta1 production)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0034241""(positive regulation of macrophage fusion)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043277""(apoptotic cell clearance)|go:""GO:0046872""(metal ion binding)|go:""GO:0048678""(response to axon injury)|go:""GO:0050821""(protein stabilization)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0071526""(semaphorin-plexin signaling pathway)|go:""GO:0097242""(amyloid-beta clearance)|go:""GO:1900272""(negative regulation of long-term synaptic potentiation)|go:""GO:1902685""(positive regulation of receptor localization to synapse)|go:""GO:1904151""(positive regulation of microglial cell mediated cytotoxicity)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:2000010""(positive regulation of protein localization to cell surface)|go:""GO:2001206""(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|rcsb pdb:7Q5W|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695|refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|efo:""Orphanet:2770""|panther:PTHR17554(orthology-group)"	"refseq:WP_002212030.1|interpro:IPR029510|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR017649(Succinylglutamic semialdehyde dehydrogenase)|go:""GO:0019544""(arginine catabolic process to glutamate)|go:""GO:0019545""(arginine catabolic process to succinate)|go:""GO:0043824""(succinylglutamate-semialdehyde dehydrogenase activity)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|refseq:YP_002346953.1|panther:PTHR11699(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	rogid:lAw8pbIH2i1IjXZl8H7zAJvQj0I632	intact-crc:B81D18B50B53338B|rigid:hZbOG7ICFehIUWhE7BIuuG6jpFc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0H8	uniprotkb:P40222	intact:EBI-2851077|uniprotkb:Q74TS0	intact:EBI-359793|uniprotkb:Q5TFJ6|uniprotkb:Q66K62|uniprotkb:Q86T54|uniprotkb:Q86T85|uniprotkb:Q86T86|uniprotkb:Q86Y86|uniprotkb:Q86YW3|uniprotkb:Q8N2Y3|uniprotkb:D3DPP6|ensembl:ENSP00000362711.1|ensembl:ENSP00000362712.3	psi-mi:q8d0h8_yerpe(display_long)|uniprotkb:y2119(locus name)|uniprotkb:amn(gene name)|psi-mi:amn(display_short)|uniprotkb:YP_2074(locus name)	psi-mi:txlna_human(display_long)|uniprotkb:TXLNA(gene name)|psi-mi:TXLNA(display_short)|uniprotkb:TXLN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851074|imex:IM-13779-5521	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011271(AMP nucleosidase)|interpro:IPR018953|interpro:IPR000845(Nucleoside phosphorylase)|go:""GO:0008714""(AMP nucleosidase activity)|go:""GO:0009116""(nucleoside metabolic process)|go:""GO:0044209""(AMP salvage)|interpro:IPR035994|interpro:IPR037109|interpro:IPR047039"	"refseq:NP_787048.1|ensembl:ENSG00000084652.16(gene)|ensembl:ENST00000373609.1(transcript)|ensembl:ENST00000373610.8(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006887""(exocytosis)|go:""GO:0016020""(membrane)|go:""GO:0019905""(syntaxin binding)|go:""GO:0042113""(B cell activation)|interpro:IPR026183|mint:P40222|reactome:R-HSA-449836|refseq:XP_016856051.1|dip:DIP-27612N|panther:PTHR16127(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pQne2oycJKd7ymLLAwCsL1/6V8U632	rogid:m6McBNTQ5VY4RNUY6PyYTj97YUk9606	intact-crc:6B3E0CD4831578D8|rigid:T+LXWZsQTszMBpwppgGo/DEvid4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PKC3	uniprotkb:Q8D065	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	intact:EBI-2847402	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:q8d065_yerpe(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:y2699(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851104|imex:IM-13779-5525	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"refseq:WP_002223447.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR017729(Type VI secretion system ATPase, ClpV1)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0016887""(ATP hydrolysis activity)|interpro:IPR036628|interpro:IPR041546|interpro:IPR004176(Clp, N-terminal)|interpro:IPR050130"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:Nh2TczmhYbmKmz+LT5cThSxQiU8632	intact-crc:F5F407055D60EDFB|rigid:EzNCyz5fqoWUjK9ZHIClwfEAFbo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PKC3	uniprotkb:A0A1U8QSD0	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	intact:EBI-2851086|uniprotkb:Q74YG8|uniprotkb:Q65AD8|uniprotkb:Q9ZGZ0	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:a0a1u8qsd0_yerpe(display_long)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851090|imex:IM-13779-5524	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"refseq:YP_094011.1|interpro:IPR025188|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:7V6Si5eR8IhffjxNCN0T7bRZj70632	intact-crc:E38BB28D7F9329A2|rigid:pF7md8EJ2d7RWWbL3RqbVTCC2b0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PKC3	uniprotkb:Q8D1A4	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	intact:EBI-2850994	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:q8d1a4_yerpe(display_long)|uniprotkb:y0798(locus name)|uniprotkb:fhuB(gene name)|psi-mi:fhuB(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851097|imex:IM-13779-5527	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"interpro:IPR000522(Bacterial transport system permease protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR037294"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:PGAfc4VH09eJJH0aF+uMggT6rQg632	intact-crc:CD2E76055D2F740B|rigid:VMxTlDrrcYP6QbtYkC8H64w+S4o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PKC3	uniprotkb:Q8D041	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	intact:EBI-2851114|uniprotkb:Q74VR7	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:q8d041_yerpe(display_long)|uniprotkb:clpA(gene name)|psi-mi:clpA(display_short)|uniprotkb:clpA1(gene name synonym)|uniprotkb:YP_1225(locus name)|uniprotkb:y2809(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851111|imex:IM-13779-5526	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|interpro:IPR013461(ATP-dependent Clp protease ATP-binding subunit clpA)|interpro:IPR027417|interpro:IPR028299|go:""GO:0005524""(ATP binding)|go:""GO:0006508""(proteolysis)|go:""GO:0008233""(peptidase activity)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0043335""(protein unfolding)|interpro:IPR036628|interpro:IPR041546|interpro:IPR050130"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:s5Ofou/48VE84z5dH0ElXjvQns8632	intact-crc:DB1607055C13A9E0|rigid:4VP4cHbJVNY1p8ZA8VPmBp8Mrpc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PKC3	uniprotkb:Q8CZR5	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	intact:EBI-2839873	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:q8czr5_yerpe(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:y3537(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851123|imex:IM-13779-5528	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"interpro:IPR028630|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006352""(DNA-templated transcription initiation)|go:""GO:0016987""(sigma factor activity)|interpro:IPR042189|interpro:IPR036388|interpro:IPR050239"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:8NwL0C9CZc1yJ2fOOz9gZqJHCMI632	intact-crc:6A4F3F525D76B4B8|rigid:yHdeCqcCHVWzmzzx5DGO64xbSdo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P26651	uniprotkb:Q8D0E1	intact:EBI-374248|intact:EBI-28988987|uniprotkb:B2RA54|ensembl:ENSP00000469647.2	intact:EBI-2851171	psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym)	psi-mi:q8d0e1_yerpe(display_long)|uniprotkb:y2338(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851168|imex:IM-13779-5531	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003398.2|ensembl:ENSG00000128016.8(gene)|ensembl:ENST00000597629.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000288""(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:0000289""(""nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0000932""(P-body)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0009611""(response to wounding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010837""(regulation of keratinocyte proliferation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019957""(C-C chemokine binding)|go:""GO:0030014""(CCR4-NOT complex)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031086""(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042594""(response to starvation)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0045616""(regulation of keratinocyte differentiation)|go:""GO:0045647""(negative regulation of erythrocyte differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051028""(mRNA transport)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0097011""(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901835""(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|go:""GO:1902172""(regulation of keratinocyte apoptotic process)|go:""GO:1904246""(negative regulation of polynucleotide adenylyltransferase activity)|go:""GO:1904582""(positive regulation of intracellular mRNA localization)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR045877|rcsb pdb:4J8S|reactome:R-HSA-450513|dip:DIP-29845N|panther:PTHR12547(orthology-group)"	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR010252(Formiminoglutamate deiminase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR032466|go:""GO:0016810""(""hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"")|interpro:IPR051607"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606	rogid:PERKzynzhTOYlkTaHwhsilRxm0U632	intact-crc:43C351A0E80DA1BF|rigid:Iixi5JKm8Z8EHtfOUJPQ+mkiy2k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6PKC3	uniprotkb:P58680	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	intact:EBI-2840970|uniprotkb:Q0WJI8	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	psi-mi:isph_yerpe(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:YPO0477(locus name)|uniprotkb:y3697(locus name)|uniprotkb:YP_3702(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851137|imex:IM-13779-5529	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"interpro:IPR003451(LytB protein)|refseq:YP_002345550.1|go:""GO:0016114""(terpenoid biosynthetic process)|go:""GO:0019288""(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:""GO:0046872""(metal ion binding)|go:""GO:0050992""(dimethylallyl diphosphate biosynthetic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|go:""GO:0051745""(4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity)|refseq:WP_002210506.1|panther:PTHR30426(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	rogid:RilZ1EP/J2M/K79PNEHVWA2tz2c632	intact-crc:F8035D8ABC3DC344|rigid:aGoKw2Y1tK0NdId1skt3dXa5IC0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YFW2	uniprotkb:O14907	intact:EBI-2851156|uniprotkb:Q74TF2|uniprotkb:A0A0H2W5I3|uniprotkb:Q7CIU3|uniprotkb:A0A384L300	intact:EBI-723259|uniprotkb:Q7LCQ4|uniprotkb:B2RD53|uniprotkb:D3DTJ6|ensembl:ENSP00000225525.3	psi-mi:a0a5p8yfw2_yerpe(display_long)|uniprotkb:btuE(gene name)|psi-mi:btuE(display_short)|uniprotkb:YPO2424(locus name)	psi-mi:tx1b3_human(display_long)|uniprotkb:Tax interaction protein 1(gene name synonym)|uniprotkb:Glutaminase-interacting protein 3(gene name synonym)|uniprotkb:TAX1BP3(gene name)|psi-mi:TAX1BP3(display_short)|uniprotkb:TIP1(gene name synonym)|uniprotkb:Tax-interacting protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851161|imex:IM-13779-5530	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029759|interpro:IPR000889(Glutathione peroxidase)|refseq:WP_002211827.1|go:""GO:0004602""(glutathione peroxidase activity)|go:""GO:0034599""(cellular response to oxidative stress)|go:""GO:0140824""(thioredoxin-dependent peroxiredoxin activity)|interpro:IPR036249|interpro:IPR033674|refseq:YP_002347387.1|panther:PTHR11592(orthology-group)"	"refseq:NP_001191627.1|refseq:NP_055419.1|ensembl:ENSG00000213977.8(gene)|ensembl:ENST00000225525.4(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:2000009""(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017268(Tax1-binding protein 3)|interpro:IPR036034|interpro:IPR050614|mint:O14907|rcsb pdb:2KG2|rcsb pdb:2L4S|rcsb pdb:2L4T|rcsb pdb:2VZ5|rcsb pdb:3GJ9|rcsb pdb:3SFJ|rcsb pdb:4E3B|rcsb pdb:4NNL|rcsb pdb:4NNM|reactome:R-HSA-5666185|panther:PTHR23136(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mnyvhshigWc836SiigsQT5ZO9+c632	rogid:w2/fv0XnJQZ+UDIXzJhdBZCtLr89606	intact-crc:AD4DE21FF1367EBE|rigid:1XwB1qnKiiRFkwjouaHru0d+K6c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14907	uniprotkb:Q8CZW9	intact:EBI-723259|uniprotkb:Q7LCQ4|uniprotkb:B2RD53|uniprotkb:D3DTJ6|ensembl:ENSP00000225525.3	intact:EBI-2851144|uniprotkb:Q74QD7	psi-mi:tx1b3_human(display_long)|uniprotkb:Tax interaction protein 1(gene name synonym)|uniprotkb:Glutaminase-interacting protein 3(gene name synonym)|uniprotkb:TAX1BP3(gene name)|psi-mi:TAX1BP3(display_short)|uniprotkb:TIP1(gene name synonym)|uniprotkb:Tax-interacting protein 1(gene name synonym)	psi-mi:q8czw9_yerpe(display_long)|uniprotkb:y3234(locus name)|uniprotkb:lacI(gene name)|psi-mi:lacI(display_short)|uniprotkb:YP_3546(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851149|imex:IM-13779-5532	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191627.1|refseq:NP_055419.1|ensembl:ENSG00000213977.8(gene)|ensembl:ENST00000225525.4(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0007266""(Rho protein signal transduction)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0015629""(actin cytoskeleton)|go:""GO:0016055""(Wnt signaling pathway)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:2000009""(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017268(Tax1-binding protein 3)|interpro:IPR036034|interpro:IPR050614|mint:O14907|rcsb pdb:2KG2|rcsb pdb:2L4S|rcsb pdb:2L4T|rcsb pdb:2VZ5|rcsb pdb:3GJ9|rcsb pdb:3SFJ|rcsb pdb:4E3B|rcsb pdb:4NNL|rcsb pdb:4NNM|reactome:R-HSA-5666185|panther:PTHR23136(orthology-group)"	"interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000843(Bacterial regulatory protein, LacI)|interpro:IPR028082|go:""GO:0003677""(DNA binding)|go:""GO:0006355""(regulation of DNA-templated transcription)|interpro:IPR046335"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:w2/fv0XnJQZ+UDIXzJhdBZCtLr89606	rogid:yJ3EWwp4rkbdKIbgx9E8PvIg0MA632	intact-crc:C7BCA19006C3B90A|rigid:hIFolVh9JNevOb93Rf5xY207m6w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YLE8	uniprotkb:Q6PKC3	intact:EBI-2841627|uniprotkb:Q74Y48|uniprotkb:A0A384L7I3|uniprotkb:A0A0H2W0Y8|uniprotkb:Q7CFX4	intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439.3	psi-mi:a0a5p8yle8_yerpe(display_long)|uniprotkb:malQ(gene name)|psi-mi:malQ(display_short)|uniprotkb:Amylomaltase(gene name synonym)|uniprotkb:Disproportionating enzyme(gene name synonym)|uniprotkb:YPO0126(locus name)	psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851130|imex:IM-13779-5533	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003385(Glycoside hydrolase, family 77)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR048458|go:""GO:0004134""(4-alpha-glucanotransferase activity)|go:""GO:0005975""(carbohydrate metabolic process)|refseq:YP_002345212.1|refseq:WP_002208925.1|panther:PTHR32438(orthology-group)"	"refseq:NP_056998.4|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066.13(gene)|ensembl:ENST00000356957.7(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR052792|mint:Q6PKC3|refseq:NP_001290376.1|panther:PTHR46497(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JdI4fLE1gbtuqHycNtXRKKfEZ7Y632	rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606	intact-crc:2D409EE6F1BBF5AF|rigid:kR4oakOU8gsXZsk7FDsiCzZgOFw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P26651	uniprotkb:Q0WIJ7	intact:EBI-374248|intact:EBI-28988987|uniprotkb:B2RA54|ensembl:ENSP00000469647.2	intact:EBI-2851185|uniprotkb:Q74QE7|uniprotkb:A0A0H2W874|uniprotkb:A0A3N4B4F6|uniprotkb:Q7CGW9|uniprotkb:A0A384LBF7	psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym)	psi-mi:q0wij7_yerpe(display_long)|uniprotkb:YPO0840(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851189|imex:IM-13779-5537	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003398.2|ensembl:ENSG00000128016.8(gene)|ensembl:ENST00000597629.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000288""(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:0000289""(""nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0000932""(P-body)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0009611""(response to wounding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010837""(regulation of keratinocyte proliferation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019957""(C-C chemokine binding)|go:""GO:0030014""(CCR4-NOT complex)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031086""(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042594""(response to starvation)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0045616""(regulation of keratinocyte differentiation)|go:""GO:0045647""(negative regulation of erythrocyte differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051028""(mRNA transport)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0097011""(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901835""(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|go:""GO:1902172""(regulation of keratinocyte apoptotic process)|go:""GO:1904246""(negative regulation of polynucleotide adenylyltransferase activity)|go:""GO:1904582""(positive regulation of intracellular mRNA localization)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR045877|rcsb pdb:4J8S|reactome:R-HSA-450513|dip:DIP-29845N|panther:PTHR12547(orthology-group)"	"interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010905(Glycosyl hydrolase, family 88)|refseq:WP_002209884.1|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR012341(Six-hairpin glycosidase)|refseq:YP_002345891.1|interpro:IPR052043"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606	rogid:OJNnsHqKxXDsmBDCvDpKtYoti2k632	intact-crc:9B3BCEC861C4C3E1|rigid:Tfv73DPiSEpImgEMP3EmERVXkYM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BS13	uniprotkb:Q8N5M4	intact:EBI-2851217|uniprotkb:Q74VF8|uniprotkb:A0A0H2W4A8|uniprotkb:Q7CHM6|uniprotkb:A0A384L9B9	intact:EBI-2851213|uniprotkb:Q8WYY7|ensembl:ENSP00000325266.3|ensembl:ENSP00000434340.1	psi-mi:a0a3n4bs13_yerpe(display_long)|uniprotkb:YPO1460(locus name)	psi-mi:ttc9c_human(display_long)|uniprotkb:TTC9C(gene name)|psi-mi:TTC9C(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851210|imex:IM-13779-5538	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002347(Glucose/ribitol dehydrogenase)|refseq:WP_002213024.1|go:""GO:0005829""(cytosol)|go:""GO:0008709""(""cholate 7-alpha-dehydrogenase (NAD+) activity"")|interpro:IPR036291|refseq:YP_002346478.1|interpro:IPR052178|panther:PTHR43618(orthology-group)"	refseq:NP_001305745.1|refseq:NP_776171.1|refseq:NP_001305741.1|refseq:NP_001305742.1|refseq:NP_001305743.1|refseq:NP_001305744.1|ensembl:ENSG00000162222.14(gene)|ensembl:ENST00000316461.9(transcript)|ensembl:ENST00000532583.1(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039663|panther:PTHR11242(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:7LflFBMVJDkIvr5R4pLM/KSUWJM632	rogid:IazckGbo0Z5cqr/m7hx7Av7BJlU9606	intact-crc:027DACD810E4E7E6|rigid:ifatMs32j6sMedvRTX0kfjB6XDU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GZS7	uniprotkb:P26651	intact:EBI-2843433|uniprotkb:Q74W70|uniprotkb:A0A0H2W1T5|uniprotkb:Q7CH58|uniprotkb:A0A3N4B3M4|uniprotkb:A0A384LC90	intact:EBI-374248|intact:EBI-28988987|uniprotkb:B2RA54|ensembl:ENSP00000469647.2	psi-mi:a0a2u2gzs7_yerpe(display_long)|uniprotkb:galB(gene name)|psi-mi:galB(display_short)|uniprotkb:galT(gene name synonym)|uniprotkb:YPO1138(locus name)	psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851178|imex:IM-13779-5534	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001937(Galactose-1-phosphate uridyl transferase, class I)|interpro:IPR005850(Galactose-1-phosphate uridyl transferase, C-terminal)|interpro:IPR005849(Galactose-1-phosphate uridyl transferase, N-terminal)|interpro:IPR019779|go:""GO:0006012""(galactose metabolic process)|go:""GO:0008108""(""UDP-glucose:hexose-1-phosphate uridylyltransferase activity"")|go:""GO:0008270""(zinc ion binding)|refseq:WP_002210749.1|interpro:IPR036265|refseq:YP_002346178.1"	"refseq:NP_003398.2|ensembl:ENSG00000128016.8(gene)|ensembl:ENST00000597629.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000288""(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:0000289""(""nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0000932""(P-body)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0009611""(response to wounding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010837""(regulation of keratinocyte proliferation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019957""(C-C chemokine binding)|go:""GO:0030014""(CCR4-NOT complex)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031086""(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042594""(response to starvation)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0045616""(regulation of keratinocyte differentiation)|go:""GO:0045647""(negative regulation of erythrocyte differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051028""(mRNA transport)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0097011""(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901835""(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|go:""GO:1902172""(regulation of keratinocyte apoptotic process)|go:""GO:1904246""(negative regulation of polynucleotide adenylyltransferase activity)|go:""GO:1904582""(positive regulation of intracellular mRNA localization)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR045877|rcsb pdb:4J8S|reactome:R-HSA-450513|dip:DIP-29845N|panther:PTHR12547(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1wWEGW8F2ZvDmG2/gCGCjsXVXE4632	rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606	intact-crc:3E30C7336CE7935D|rigid:fubbsRXLb7uom1kN9vQM8xkrwSk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P26651	uniprotkb:Q8ZHG0	intact:EBI-374248|intact:EBI-28988987|uniprotkb:B2RA54|ensembl:ENSP00000469647.2	intact:EBI-2842527|uniprotkb:Q8CKL4|uniprotkb:Q0WIA2|uniprotkb:Q74QH2	psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym)	psi-mi:agua_yerpe(display_long)|uniprotkb:aguA(gene name)|psi-mi:aguA(display_short)|uniprotkb:Agmatine iminohydrolase(gene name synonym)|uniprotkb:YPO0939(locus name)|uniprotkb:y3325(locus name)|uniprotkb:YP_3503(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851203|imex:IM-13779-5536	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003398.2|ensembl:ENSG00000128016.8(gene)|ensembl:ENST00000597629.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000288""(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:0000289""(""nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0000932""(P-body)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0009611""(response to wounding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010837""(regulation of keratinocyte proliferation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019957""(C-C chemokine binding)|go:""GO:0030014""(CCR4-NOT complex)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031086""(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042594""(response to starvation)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0045616""(regulation of keratinocyte differentiation)|go:""GO:0045647""(negative regulation of erythrocyte differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051028""(mRNA transport)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0097011""(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901835""(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|go:""GO:1902172""(regulation of keratinocyte apoptotic process)|go:""GO:1904246""(negative regulation of polynucleotide adenylyltransferase activity)|go:""GO:1904582""(positive regulation of intracellular mRNA localization)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR045877|rcsb pdb:4J8S|reactome:R-HSA-450513|dip:DIP-29845N|panther:PTHR12547(orthology-group)"	"interpro:IPR017754(Agmatine deiminase)|interpro:IPR007466(Peptidyl-arginine deiminase, Porphyromonas-type)|go:""GO:0004668""(protein-arginine deiminase activity)|go:""GO:0009446""(putrescine biosynthetic process)|go:""GO:0047632""(agmatine deiminase activity)|refseq:YP_002345986.1|panther:PTHR31377(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606	rogid:wqVmguxc+OwAcDUbyMd1UcCWH/o632	intact-crc:B5287A1EE851F729|rigid:PrhfMOjQUH75XceWTXr+75Kpl7c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P26651	uniprotkb:Q8Z9S7	intact:EBI-374248|intact:EBI-28988987|uniprotkb:B2RA54|ensembl:ENSP00000469647.2	intact:EBI-2843785|uniprotkb:Q74PA2|uniprotkb:Q0W9R8|uniprotkb:Q8CZF5	psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym)	psi-mi:glmu_yerpe(display_long)|uniprotkb:glmU(gene name)|psi-mi:glmU(display_short)|uniprotkb:YPO4119(locus name)|uniprotkb:y4133(locus name)|uniprotkb:YP_4026(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851196|imex:IM-13779-5535	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003398.2|ensembl:ENSG00000128016.8(gene)|ensembl:ENST00000597629.3(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000288""(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:0000289""(""nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0000932""(P-body)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006402""(mRNA catabolic process)|go:""GO:0009611""(response to wounding)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0010837""(regulation of keratinocyte proliferation)|go:""GO:0019899""(enzyme binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019957""(C-C chemokine binding)|go:""GO:0030014""(CCR4-NOT complex)|go:""GO:0030099""(myeloid cell differentiation)|go:""GO:0031072""(heat shock protein binding)|go:""GO:0031086""(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0042594""(response to starvation)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0045616""(regulation of keratinocyte differentiation)|go:""GO:0045647""(negative regulation of erythrocyte differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051028""(mRNA transport)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:0060218""(hematopoietic stem cell differentiation)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070063""(RNA polymerase binding)|go:""GO:0070935""(3'-UTR-mediated mRNA stabilization)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0097011""(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901835""(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:""GO:1902037""(negative regulation of hematopoietic stem cell differentiation)|go:""GO:1902172""(regulation of keratinocyte apoptotic process)|go:""GO:1904246""(negative regulation of polynucleotide adenylyltransferase activity)|go:""GO:1904582""(positive regulation of intracellular mRNA localization)|go:""GO:1990904""(ribonucleoprotein complex)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR045877|rcsb pdb:4J8S|reactome:R-HSA-450513|dip:DIP-29845N|panther:PTHR12547(orthology-group)"	"rcsb pdb:4FCE|interpro:IPR029044|interpro:IPR005882(UDP-N-acetylglucosamine pyrophosphorylase)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR018357|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR025877|go:""GO:0000287""(magnesium ion binding)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0003977""(UDP-N-acetylglucosamine diphosphorylase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006048""(UDP-N-acetylglucosamine biosynthetic process)|go:""GO:0008360""(regulation of cell shape)|go:""GO:0009245""(lipid A biosynthetic process)|go:""GO:0009252""(peptidoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0019134""(glucosamine-1-phosphate N-acetyltransferase activity)|go:""GO:0071555""(cell wall organization)|interpro:IPR038009|refseq:WP_002215550.1|refseq:YP_002348970.1|interpro:IPR050065|panther:PTHR43584(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606	rogid:9qnSgGL+fCmXV2kMl5dYnODFWqw632	intact-crc:2AAA5B1EE9C3A5E1|rigid:UnHYjSUfDur3/9LGjYBRykydyr4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A2A3L6	uniprotkb:Q8ZC18	intact:EBI-2851251|uniprotkb:Q5T3H7|ensembl:ENSP00000357219.3|ensembl:ENSP00000517290.1	intact:EBI-2851256|uniprotkb:Q0WC74	psi-mi:ttc24_human(display_long)|uniprotkb:TTC24(gene name)|psi-mi:TTC24(display_short)	psi-mi:rdgc_yerpe(display_long)|uniprotkb:rdgC(gene name)|psi-mi:rdgC(display_short)|uniprotkb:YPO3212(locus name)|uniprotkb:y0974(locus name)|uniprotkb:YP_0723(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851248|imex:IM-13779-5542	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_001099139.2|ensembl:ENSG00000187862.13(gene)|ensembl:ENSG00000291760.1(gene)|ensembl:ENST00000368236.8(transcript)|ensembl:ENST00000708590.1(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024812|panther:PTHR47050(orthology-group)	"interpro:IPR007476(Putative exonuclease, RdgC)|refseq:WP_002208691.1|go:""GO:0000018""(regulation of DNA recombination)|go:""GO:0003690""(double-stranded DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006310""(DNA recombination)|go:""GO:0043590""(bacterial nucleoid)|refseq:YP_002348114.1|panther:PTHR38103(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5H8thyQvVbYbNl5p3gbAEqGqDO89606	rogid:fjThsIbDKuwXOUDaMBLbS+Ab+F0632	intact-crc:0E8F4EF6BEB3D4F7|rigid:WI6hRgHPibNtDDtxnhOY4X/FVRE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q6DKK2	uniprotkb:A0A5P8YAV7	intact:EBI-948354|uniprotkb:Q7L3U8|uniprotkb:Q9NXB2|uniprotkb:A8MZ52|uniprotkb:B3KP62|uniprotkb:B4DN65|uniprotkb:Q9H6G3|uniprotkb:Q2M248|ensembl:ENSP00000261647.5	intact:EBI-2839792|uniprotkb:Q74QU9|uniprotkb:Q0WA24|uniprotkb:Q7CG16|uniprotkb:A0A0H2W8V3	psi-mi:ttc19_human(display_long)|uniprotkb:TTC19(gene name)|psi-mi:TTC19(display_short)	psi-mi:a0a5p8yav7_yerpe(display_long)|uniprotkb:pelY(gene name)|psi-mi:pelY(display_short)|uniprotkb:YPO3994(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851277|imex:IM-13779-5541	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:1460""|ensembl:ENSG00000011295.16(gene)|ensembl:ENST00000261647.10(transcript)|go:""GO:0000281""(mitotic cytokinesis)|go:""GO:0005739""(mitochondrion)|go:""GO:0005743""(mitochondrial inner membrane)|go:""GO:0005813""(centrosome)|go:""GO:0030496""(midbody)|go:""GO:0034551""(mitochondrial respiratory chain complex III assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040395|mint:Q6DKK2|reactome:R-HSA-9865881|refseq:NP_001258349.1|refseq:NP_060245.3|panther:PTHR13143(orthology-group)"	"interpro:IPR010702(Periplasmic pectate lyase)|refseq:YP_002348864.1|refseq:WP_002209555.1|go:""GO:0016837""(carbon-oxygen lyase activity, acting on polysaccharides)|go:""GO:0042597""(periplasmic space)|go:""GO:0045490""(pectin catabolic process)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:skTQJ+iUoHBb06IqVhoprLMYEtA9606	rogid:TdSmcoWgW+r5eNyU5ieC4Vae68s632	intact-crc:D9D46C96BED98034|rigid:SVOYtW9KhRRQcTQILn4zb94UAy4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W6Y0	uniprotkb:Q9ULT0	intact:EBI-2851229	intact:EBI-2844096|uniprotkb:Q6PIX4|uniprotkb:Q9BUS3|uniprotkb:Q8ND67|uniprotkb:Q2T9J9|ensembl:ENSP00000316699.5	psi-mi:a0a0h2w6y0_yerpe(display_long)|uniprotkb:NCTC5923_03272(orf name)|uniprotkb:YP_2938(locus name)|uniprotkb:y3557(locus name)	psi-mi:ttc7a_human(display_long)|uniprotkb:TTC7A(gene name)|psi-mi:TTC7A(display_short)|uniprotkb:KIAA1140(gene name synonym)|uniprotkb:TTC7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851226|imex:IM-13779-5543	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR031381|uniprotkb:A0A6B3T0Z7(uniprot-removed-ac)|go:""GO:0005886""(plasma membrane)|refseq:WP_002214224.1"	"ensembl:ENSG00000068724.18(gene)|ensembl:ENST00000319190.11(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0006879""(intracellular iron ion homeostasis)|go:""GO:0030097""(hemopoiesis)|go:""GO:0046854""(phosphatidylinositol phosphate biosynthetic process)|go:""GO:0072659""(protein localization to plasma membrane)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR045819|interpro:IPR051722|mint:Q9ULT0|refseq:NP_001275880.1|refseq:NP_001275882.1|refseq:NP_001275884.1|refseq:NP_065191.2|efo:""Orphanet:2300""|efo:""Orphanet:436252""|panther:PTHR23083(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jpemEe1g8Pg5hCUGcqrXm8QtFic632	rogid:ZxOOuhpKuSn+quIkbCHDb1HVCjo9606	intact-crc:5F14E9F10219A044|rigid:DBciTDmJ6zX05BmyUDHDuGdNmQI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P53804	uniprotkb:A0A454XXH7	intact:EBI-2681313|uniprotkb:P78477|uniprotkb:A8K7H7|uniprotkb:Q9UEK4|uniprotkb:Q569I2|uniprotkb:Q6P578|uniprotkb:B2RPA7|uniprotkb:O60767|uniprotkb:P78476|uniprotkb:D3DSG9|uniprotkb:D3DSH2|uniprotkb:D3DSH3|intact:EBI-28966952|ensembl:ENSP00000346791.2|ensembl:ENSP00000381981.2|ensembl:ENSP00000403943.2|ensembl:ENSP00000408456.2	intact:EBI-2851240|uniprotkb:Q74Y15|uniprotkb:A0A0H2W158|uniprotkb:Q7CFV5|uniprotkb:A0A384K924	psi-mi:ttc3_human(display_long)|uniprotkb:DCRR1(gene name synonym)|uniprotkb:RNF105(gene name synonym)|uniprotkb:TPRD(gene name synonym)|uniprotkb:Protein DCRR1(gene name synonym)|uniprotkb:RING finger protein 105(gene name synonym)|uniprotkb:TPR repeat protein D(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 3(gene name synonym)|uniprotkb:TTC3(gene name)|psi-mi:TTC3(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TTC3(gene name synonym)	psi-mi:a0a454xxh7_yerpe(display_long)|uniprotkb:YPO0168(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851237|imex:IM-13779-5539	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001307633.1|refseq:XP_011528042.1|refseq:NP_001001894.1|refseq:NP_003307.3|ensembl:ENSG00000182670.14(gene)|ensembl:ENST00000354749.6(transcript)|ensembl:ENST00000399017.6(transcript)|ensembl:ENST00000418766.6(transcript)|ensembl:ENST00000450533.6(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005730""(nucleolus)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR043866|mint:P53804|refseq:NP_001317610.1|refseq:NP_001317611.1|refseq:NP_001317612.1|panther:PTHR17550(orthology-group)"	interpro:IPR027417|refseq:WP_002215686.1|interpro:IPR033186|refseq:YP_002345254.1|interpro:IPR051162|panther:PTHR30121(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:AUMk8fif75q+OlZMhyo2I95YkXQ9606	rogid:7T8Io5VjMpoAGWF393x9GYtAK2w632	intact-crc:C37B10080AAE349D|rigid:k58OrWjsI/raCgQjciTKkDnCo1k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99614	uniprotkb:A0A5P8YGX7	intact:EBI-742074|uniprotkb:Q9BVT3|uniprotkb:B2RCT2|uniprotkb:D3DQJ8|ensembl:ENSP00000231238.4|ensembl:ENSP00000429225.1|ensembl:ENSP00000507891.1	intact:EBI-2851265|uniprotkb:Q74T83|uniprotkb:Q0WE33|uniprotkb:Q7CJ53|uniprotkb:A0A384KBR0	psi-mi:ttc1_human(display_long)|uniprotkb:TTC1(gene name)|psi-mi:TTC1(display_short)|uniprotkb:TPR1(gene name synonym)	psi-mi:a0a5p8ygx7_yerpe(display_long)|uniprotkb:YPO2491(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851270|imex:IM-13779-5540	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001269429.1|refseq:NP_003305.1|ensembl:ENSG00000113312.12(gene)|ensembl:ENST00000231238.10(transcript)|ensembl:ENST00000522793.5(transcript)|ensembl:ENST00000682719.1(transcript)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006457""(protein folding)|go:""GO:0051082""(unfolded protein binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR052769|panther:PTHR46014(orthology-group)"	"interpro:IPR027282|interpro:IPR034746|interpro:IPR005565(Haemolysin activator HlyB)|interpro:IPR013686(Polypeptide-transport-associated, ShlB-type)|interpro:IPR035251|refseq:WP_002210212.1|go:""GO:0008320""(protein transmembrane transporter activity)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046819""(protein secretion by the type V secretion system)|go:""GO:0098046""(type V protein secretion system complex)|refseq:YP_002347455.1|interpro:IPR051544|panther:PTHR34597(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jpDASWCrto0zMhBm3Cj9aDQURm09606	rogid:OGj9bfN4PBupBxOaODA+a4060Uw632	intact-crc:E8186F112CCECA55|rigid:1qhZ6o0wVlAbUk1Z2PUlpr24eH0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96SJ8	uniprotkb:A0A380PJJ5	intact:EBI-2851325|uniprotkb:Q8NBI9|uniprotkb:Q6UY44|ensembl:ENSP00000339820.3|ensembl:ENSP00000429993.2	intact:EBI-2845694|uniprotkb:Q0WI50|uniprotkb:Q7CGN7	psi-mi:tsn18_human(display_long)|uniprotkb:TSPAN18(gene name)|psi-mi:TSPAN18(display_short)|uniprotkb:UNQ3042/PRO9858(orf name)	psi-mi:a0a380pjj5_yerpe(display_long)|uniprotkb:iucD(gene name)|psi-mi:iucD(display_short)|uniprotkb:YPO0993(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851331|imex:IM-13779-5548	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011518761.1|refseq:XP_006718436.1|refseq:NP_570139.3|ensembl:ENSG00000157570.12(gene)|ensembl:ENST00000340160.7(transcript)|ensembl:ENST00000520358.7(transcript)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0007599""(hemostasis)|go:""GO:0017156""(calcium-ion regulated exocytosis)|go:""GO:0051649""(establishment of localization in cell)|go:""GO:1903670""(regulation of sprouting angiogenesis)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|panther:PTHR19282(orthology-group)"	"interpro:IPR025700|refseq:WP_002211647.1|go:""GO:0047091""(""L-lysine 6-monooxygenase (NADPH) activity"")|interpro:IPR036188|refseq:YP_002346038.1|panther:PTHR42802(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SXEcUHaS/1QWa1iQpuJ5LO0/vrU9606	rogid:Yq7E3I4Gh8JvT7cRCoaBFJsJ5fU632	intact-crc:32EDC0B54F493434|rigid:dRsk2pGuNOmIrhw68+fKK0gZOXY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CZK5	uniprotkb:Q99598	intact:EBI-2845872|uniprotkb:Q74QX9	intact:EBI-21353855|ensembl:ENSP00000355599.3|uniprotkb:B1APC6	psi-mi:q8czk5_yerpe(display_long)|uniprotkb:fba(gene name)|psi-mi:fba(display_short)|uniprotkb:YP_3323(locus name)|uniprotkb:y3869(locus name)	psi-mi:tsnax_human(display_long)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym)|uniprotkb:Translin-associated factor X(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851318|imex:IM-13779-5546	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000771(Ketose-bisphosphate aldolase, class-II)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016832""(aldehyde-lyase activity)|interpro:IPR050246"	"ensembl:ENSG00000116918.15(gene)|ensembl:ENST00000366639.9(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003697""(single-stranded DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0004521""(RNA endonuclease activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007283""(spermatogenesis)|go:""GO:0030154""(cell differentiation)|rcsb pdb:3QB5|go:""GO:0030422""(siRNA processing)|go:""GO:0031687""(A2A adenosine receptor binding)|go:""GO:0035194""(regulatory ncRNA-mediated post-transcriptional gene silencing)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0046872""(metal ion binding)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:1902555""(endoribonuclease complex)|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|interpro:IPR016069(Translin, C-terminal)|interpro:IPR036081|mint:Q99598|rcsb pdb:3PJA|reactome:R-HSA-426486|uniprotkb:A0A024R3V8(uniprot-removed-ac)|dip:DIP-29463N|refseq:NP_005990.1|panther:PTHR10741(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:F4QkMnJWZdUUOo6ENRO8BbcEL+I632	rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606	intact-crc:F3BBF1CBA7A1174B|rigid:+FUWj53UTM2vnUjI5GfI4AW7zlA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WVT3	uniprotkb:A0A2U2GUN8	intact:EBI-2819919|uniprotkb:B3KV01|uniprotkb:Q8WVW1|uniprotkb:Q9Y395|uniprotkb:D6W4Y2|ensembl:ENSP00000324318.5|ensembl:ENSP00000371544.2	intact:EBI-2844713|uniprotkb:Q74T17|uniprotkb:Q0WDV8|uniprotkb:Q7CJ97|uniprotkb:A0A3N4AZU4|uniprotkb:A0A384KTX0	psi-mi:tpc12_human(display_long)|uniprotkb:TRAPPC12(gene name)|psi-mi:TRAPPC12(display_short)|uniprotkb:TTC15(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 15(gene name synonym)|uniprotkb:TRAMM(gene name synonym)|uniprotkb:Trafficking of membranes and mitosis(gene name synonym)|uniprotkb:CGI-87(orf name)	psi-mi:a0a2u2gun8_yerpe(display_long)|uniprotkb:YPO2569(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851291|imex:IM-13779-5547	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000171853.16(gene)|ensembl:ENST00000324266.10(transcript)|ensembl:ENST00000382110.6(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0030008""(TRAPP complex)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0051310""(metaphase chromosome alignment)|go:""GO:0090234""(regulation of kinetochore assembly)|go:""GO:0099022""(vesicle tethering)|go:""GO:1905342""(positive regulation of protein localization to kinetochore)|go:""GO:1990072""(TRAPPIII protein complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-HSA-8876198|refseq:NP_001308031.1|refseq:NP_057114.5|dip:DIP-48283N|efo:""Orphanet:500144""|panther:PTHR21581(orthology-group)"	"rcsb pdb:3OXP|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_002210291.1|go:""GO:0005737""(cytoplasm)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|refseq:YP_002347530.1|interpro:IPR051351"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4uQz/ucWKhi1VZOdFWBdGAJ69MY9606	rogid:WexLHH5KTrnggqyPy38AGIRlsdI632	intact-crc:664C679C1FEABF15|rigid:8jxtbOu7yEJuaLdRmvUf75KVwLo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7Z4L5	uniprotkb:P58582	intact:EBI-2851301|uniprotkb:Q53T84|uniprotkb:Q6PIF5|uniprotkb:A8MUZ3|uniprotkb:Q8NCN3|uniprotkb:Q9HAK8|uniprotkb:Q96MA4|uniprotkb:Q6P4A1|uniprotkb:Q3LIE4|ensembl:ENSP00000243344.7|ensembl:ENSP00000506276.1|ensembl:ENSP00000506400.1	intact:EBI-2846820|uniprotkb:Q0WIA6	psi-mi:tt21b_human(display_long)|uniprotkb:TTC21B(gene name)|psi-mi:TTC21B(display_short)|uniprotkb:KIAA1992(gene name synonym)|uniprotkb:Nbla10696(orf name)|uniprotkb:IFT139(gene name synonym)|uniprotkb:Intraflagellar transport 139 homolog(gene name synonym)	psi-mi:gshb_yerpe(display_long)|uniprotkb:gshB(gene name)|psi-mi:gshB(display_short)|uniprotkb:GSH synthetase(gene name synonym)|uniprotkb:Glutathione synthase(gene name synonym)|uniprotkb:YPO0935(locus name)|uniprotkb:y3321(locus name)|uniprotkb:YP_3507(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851298|imex:IM-13779-5545	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000123607.16(gene)|ensembl:ENST00000243344.8(transcript)|ensembl:ENST00000680888.1(transcript)|ensembl:ENST00000681952.1(transcript)|go:""GO:0003682""(chromatin binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005856""(cytoskeleton)|go:""GO:0005929""(cilium)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0007224""(smoothened signaling pathway)|go:""GO:0008589""(regulation of smoothened signaling pathway)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0021591""(ventricular system development)|go:""GO:0021702""(cerebellar Purkinje cell differentiation)|go:""GO:0021798""(forebrain dorsal/ventral pattern formation)|go:""GO:0030991""(intraciliary transport particle A)|go:""GO:0035721""(intraciliary retrograde transport)|go:""GO:0060020""(Bergmann glial cell differentiation)|go:""GO:0060271""(cilium assembly)|go:""GO:0061512""(protein localization to cilium)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097499""(protein localization to non-motile cilium)|go:""GO:0097542""(ciliary tip)|go:""GO:1903999""(negative regulation of eating behavior)|go:""GO:1905799""(regulation of intraciliary retrograde transport)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040364|mint:Q7Z4L5|rcsb pdb:8BBE|rcsb pdb:8BBG|rcsb pdb:8FGW|reactome:R-HSA-5610787|reactome:R-HSA-5620924|refseq:NP_079029.3|efo:""Orphanet:474""|efo:""Orphanet:93591""|panther:PTHR14699(orthology-group)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR006284(Glutathione synthetase, prokaryotic)|interpro:IPR004218(Prokaryotic glutathione synthetase, ATP-binding)|interpro:IPR004215(Prokaryotic glutathione synthetase, N-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|refseq:WP_002209976.1|go:""GO:0004363""(glutathione synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|refseq:YP_002345982.1|panther:PTHR21621(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y1VB2y4oBho3fxf1gOl0LAz2u8o9606	rogid:2PCcRO+ezg1vmWad2fXePKESKh4632	intact-crc:68BA294E081851E4|rigid:7CVFs7RsbfNqMCckfi+CHaV2HZY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8WVT3	uniprotkb:A0A2S9PJ11	intact:EBI-2819919|uniprotkb:B3KV01|uniprotkb:Q8WVW1|uniprotkb:Q9Y395|uniprotkb:D6W4Y2|ensembl:ENSP00000324318.5|ensembl:ENSP00000371544.2	intact:EBI-2843240|uniprotkb:Q74SW1|uniprotkb:Q7CJT3|uniprotkb:A0A380PL96|uniprotkb:Q0WDP0	psi-mi:tpc12_human(display_long)|uniprotkb:TRAPPC12(gene name)|psi-mi:TRAPPC12(display_short)|uniprotkb:TTC15(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 15(gene name synonym)|uniprotkb:TRAMM(gene name synonym)|uniprotkb:Trafficking of membranes and mitosis(gene name synonym)|uniprotkb:CGI-87(orf name)	psi-mi:a0a2s9pj11_yerpe(display_long)|uniprotkb:proW(gene name)|psi-mi:proW(display_short)|uniprotkb:YPO2646(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851284|imex:IM-13779-5544	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000171853.16(gene)|ensembl:ENST00000324266.10(transcript)|ensembl:ENST00000382110.6(transcript)|go:""GO:0000776""(kinetochore)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0030008""(TRAPP complex)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0051310""(metaphase chromosome alignment)|go:""GO:0090234""(regulation of kinetochore assembly)|go:""GO:0099022""(vesicle tethering)|go:""GO:1905342""(positive regulation of protein localization to kinetochore)|go:""GO:1990072""(TRAPPIII protein complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-HSA-8876198|refseq:NP_001308031.1|refseq:NP_057114.5|dip:DIP-48283N|efo:""Orphanet:500144""|panther:PTHR21581(orthology-group)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|refseq:WP_002212209.1|interpro:IPR035906|refseq:YP_002347598.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4uQz/ucWKhi1VZOdFWBdGAJ69MY9606	rogid:BBwCIsPUr1k5paTb1ggfStKFewc632	intact-crc:14FBEECDCEB0F6C5|rigid:K1HIWu9KxghF8WI9uml9/ltxxKw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92574	uniprotkb:Q8CZT9	intact:EBI-1047085|uniprotkb:Q5VVN5|ensembl:ENSP00000298552.3|ensembl:ENSP00000495158.1|ensembl:ENSP00000495533.2|ensembl:ENSP00000495830.2|ensembl:ENSP00000496263.1|intact:EBI-1386638|intact:EBI-28978933|uniprotkb:B7Z897	intact:EBI-2842220	psi-mi:tsc1_human(display_long)|uniprotkb:TSC1(gene name)|psi-mi:TSC1(display_short)|uniprotkb:KIAA0243(gene name synonym)|uniprotkb:Tuberous sclerosis 1 protein(gene name synonym)|uniprotkb:TSC(gene name synonym)	psi-mi:q8czt9_yerpe(display_long)|uniprotkb:hmwP2(gene name)|psi-mi:hmwP2(display_short)|uniprotkb:y3410(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851345|imex:IM-13779-5549	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000165699.16(gene)|ensembl:ENST00000298552.9(transcript)|ensembl:ENST00000490179.4(transcript)|ensembl:ENST00000643875.1(transcript)|ensembl:ENST00000646440.2(transcript)|ensembl:ENST00000646625.1(transcript)|go:""GO:0001822""(kidney development)|go:""GO:0001843""(neural tube closure)|go:""GO:0001952""(regulation of cell-matrix adhesion)|go:""GO:0002250""(adaptive immune response)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005811""(lipid droplet)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0005938""(cell cortex)|go:""GO:0006813""(potassium ion transport)|go:""GO:0007160""(cell-matrix adhesion)|go:""GO:0008283""(cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008306""(associative learning)|go:""GO:0008344""(adult locomotory behavior)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016242""(negative regulation of macroautophagy)|go:""GO:0021766""(hippocampus development)|go:""GO:0021987""(cerebral cortex development)|go:""GO:0030027""(lamellipodium)|go:""GO:0030030""(cell projection organization)|go:""GO:0030544""(Hsp70 protein binding)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032868""(response to insulin)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033596""(TSC1-TSC2 complex)|go:""GO:0036294""(cellular response to decreased oxygen levels)|go:""GO:0042030""(ATPase inhibitor activity)|go:""GO:0042552""(myelination)|go:""GO:0043379""(memory T cell differentiation)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0045792""(negative regulation of cell size)|go:""GO:0046323""(D-glucose import)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050808""(synapse organization)|go:""GO:0050821""(protein stabilization)|go:""GO:0051087""(protein-folding chaperone binding)|go:""GO:0051492""(regulation of stress fiber assembly)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0055007""(cardiac muscle cell differentiation)|go:""GO:0090630""(activation of GTPase activity)|go:""GO:0101031""(protein folding chaperone complex)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR007483(Hamartin)|mint:Q92574|rcsb pdb:4Z6Y|rcsb pdb:5EJC|rcsb pdb:7DL2|reactome:R-HSA-1632852|reactome:R-HSA-165181|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8854214|refseq:NP_000359.1|refseq:NP_001155898.1|refseq:NP_001155899.1|refseq:XP_005272268.1|refseq:XP_006717334.1|refseq:XP_011517281.1|refseq:XP_016870585.1|refseq:XP_016870586.1|efo:""Orphanet:210159""|efo:""Orphanet:269008""|efo:""Orphanet:538""|efo:""Orphanet:805""|panther:PTHR15154(orthology-group)|ensembl:ENSP00000298552.3|ensembl:ENSP00000495533.2|ensembl:ENST00000643072.1|ensembl:ENSP00000496691.1|ensembl:ENSP00000495158.1|ensembl:ENSP00000495830.2|ensembl:ENSP00000496263.1"	"interpro:IPR010071(Amino acid adenylation)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001242(Condensation domain)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR023213|go:""GO:0003824""(catalytic activity)|interpro:IPR036736|interpro:IPR042099|interpro:IPR045851|interpro:IPR029063"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Frpc4GasNNqHfgr9tr7TUPfKZx09606	rogid:ao0VQq4H/q18sVJ9ZK5p412pxhg632	intact-crc:8728356AC088BC06|rigid:Cel1Irqm0i45g8A6HX5Dp0zHx2U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1A4	uniprotkb:Q16881	intact:EBI-2850994	intact:EBI-716617|uniprotkb:Q6FI31|uniprotkb:Q6VB40|uniprotkb:Q6VB41|uniprotkb:Q6VB42|uniprotkb:Q6VBP2|uniprotkb:Q6VBP3|uniprotkb:Q6VBP4|uniprotkb:Q6VBP5|uniprotkb:Q6VBP9|uniprotkb:Q6VBQ0|uniprotkb:Q6YNQ1|uniprotkb:Q8WVC8|uniprotkb:Q99475|uniprotkb:Q9UES8|uniprotkb:Q76P53|uniprotkb:Q7LA96|uniprotkb:Q9UH79|uniprotkb:B7Z1F4|uniprotkb:B7Z3Y8|uniprotkb:B7Z904|uniprotkb:E9PMY9|uniprotkb:F5H780|ensembl:ENSP00000434516.1	psi-mi:q8d1a4_yerpe(display_long)|uniprotkb:y0798(locus name)|uniprotkb:fhuB(gene name)|psi-mi:fhuB(display_short)	psi-mi:trxr1_human(display_long)|uniprotkb:KDRF(gene name synonym)|uniprotkb:Thioredoxin reductase TR1(gene name synonym)|uniprotkb:KM-102-derived reductase-like factor(gene name synonym)|uniprotkb:GRIM12(gene name synonym)|uniprotkb:TXNRD1(gene name)|psi-mi:TXNRD1(display_short)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 12 protein(gene name synonym)|uniprotkb:Peroxidase TXNRD1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851352|imex:IM-13779-5553	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000522(Bacterial transport system permease protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0022857""(transmembrane transporter activity)|interpro:IPR037294"	"refseq:NP_001087240.1|refseq:NP_003321.3|refseq:NP_877393.1|refseq:NP_877419.1|refseq:NP_877420.1|refseq:NP_001248374.1|refseq:NP_001248375.1|ensembl:ENSG00000198431.18(gene)|ensembl:ENST00000525566.6(transcript)|go:""GO:0001650""(fibrillar center)|go:""GO:0001707""(mesoderm formation)|go:""GO:0004791""(""thioredoxin-disulfide reductase (NADPH) activity"")|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005829""(cytosol)|go:""GO:0007165""(signal transduction)|go:""GO:0008283""(cell population proliferation)|go:""GO:0042802""(identical protein binding)|go:""GO:0045454""(cell redox homeostasis)|go:""GO:0050137""(NADPH peroxidase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071949""(FAD binding)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|interpro:IPR036249|interpro:IPR046952|mint:Q16881|rcsb pdb:2CFY|rcsb pdb:2J3N|rcsb pdb:2ZZ0|rcsb pdb:2ZZB|rcsb pdb:2ZZC|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:7X1R|reactome:R-HSA-1989781|reactome:R-HSA-2408550|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5263617|reactome:R-HSA-5336415|reactome:R-HSA-5628897|reactome:R-HSA-9818027|panther:PTHR48105(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PGAfc4VH09eJJH0aF+uMggT6rQg632	rogid:0CrcaHgTDl4AIU4V2zXt3u9Pet89606	intact-crc:FF48709BCD15D696|rigid:eFhKLkSH1dyXiRiDwlutZcCZnTg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1R8	uniprotkb:P48995	intact:EBI-2844176	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:q8d1r8_yerpe(display_long)|uniprotkb:y0112(locus name)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851377|imex:IM-13779-5554	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR016639(Glutathione S-transferase, predicted)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|go:""GO:0004364""(glutathione transferase activity)|interpro:IPR040079|interpro:IPR036249|interpro:IPR036282|refseq:WP_002220229.1|interpro:IPR047047"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t+PPnZeaiT6XhlJXTLVuOsYXAMI632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:C547657E767E00CE|rigid:xoDCM3BoOanC4ZBGp7maTZITq7U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48995	uniprotkb:Q7CGT3	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	intact:EBI-2851362|uniprotkb:Q74Q94	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	psi-mi:ygfz_yerpe(display_long)|uniprotkb:YPO0898(locus name)|uniprotkb:y3283(locus name)|uniprotkb:YP_3595(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851359|imex:IM-13779-5550	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"interpro:IPR029043|interpro:IPR023758|interpro:IPR017703(Folate-binding, YgfZ)|refseq:WP_002209940.1|go:""GO:0005542""(folic acid binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0008033""(tRNA processing)|go:""GO:0009451""(RNA modification)|go:""GO:0016226""(iron-sulfur cluster assembly)|interpro:IPR048451|refseq:YP_002345947.1|interpro:IPR045179|panther:PTHR22602(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	rogid:qsp6c7iyJPkACUpbuAv36AvJDYs632	intact-crc:3D87B5D0AB7D23B6|rigid:0yZNQ6NmoZxsdQt++UbEdL3dnKo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CH25	uniprotkb:P48995	intact:EBI-2841669|uniprotkb:Q74S59	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:syp_yerpe(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO1068(locus name)|uniprotkb:YP_2781(locus name)|uniprotkb:y3109(locus name)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851370|imex:IM-13779-5551	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR044140|interpro:IPR002314(""Aminoacyl-tRNA synthetase, class II (G, H, P and S)"")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|go:""GO:0002161""(aminoacyl-tRNA deacylase activity)|go:""GO:0004827""(proline-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006433""(prolyl-tRNA aminoacylation)|refseq:YP_002346112.1|refseq:WP_002212156.1|interpro:IPR036621|interpro:IPR036754|interpro:IPR050062|interpro:IPR045864|panther:PTHR42753(orthology-group)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:2qYbc5WfSr9brbuePLTbeGWdx4c632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:6C186AD0AAA1D60D|rigid:LU+uVmUCdCt+sppCijpjDroDSik	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P49815	uniprotkb:Q65AE7	intact:EBI-396587|uniprotkb:O75275|uniprotkb:Q8TAZ1|uniprotkb:B4DRN2|uniprotkb:A7E2E2|uniprotkb:B4DIQ7|uniprotkb:Q4LE71|uniprotkb:C9J378|uniprotkb:B4DIL8|uniprotkb:B7Z2B8|ensembl:ENSP00000219476.3	intact:EBI-2847916|uniprotkb:A0A3N4BMH0|uniprotkb:Q9ZGZ5|uniprotkb:A0A384LBG0|uniprotkb:A0A1U8QRS1|uniprotkb:Q7ARB3	psi-mi:tsc2_human(display_long)|uniprotkb:TSC2(gene name)|psi-mi:TSC2(display_short)|uniprotkb:Tuberous sclerosis 2 protein(gene name synonym)|uniprotkb:TSC4(gene name synonym)	psi-mi:q65ae7_yerpe(display_long)|uniprotkb:YPMT1.73(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851338|imex:IM-13779-5552	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:210159""|efo:""Orphanet:269001""|efo:""Orphanet:269008""|efo:""Orphanet:538""|efo:""Orphanet:805""|efo:""Orphanet:88924""|ensembl:ENSG00000103197.20(gene)|ensembl:ENST00000219476.9(transcript)|go:""GO:0001843""(neural tube closure)|go:""GO:0005096""(GTPase activator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006469""(negative regulation of protein kinase activity)|go:""GO:0006606""(protein import into nucleus)|go:""GO:0006897""(endocytosis)|go:""GO:0007507""(heart development)|go:""GO:0008104""(protein localization)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0014069""(postsynaptic density)|go:""GO:0016020""(membrane)|go:""GO:0016192""(vesicle-mediated transport)|go:""GO:0016239""(positive regulation of macroautophagy)|go:""GO:0019902""(phosphatase binding)|go:""GO:0030100""(regulation of endocytosis)|go:""GO:0030178""(negative regulation of Wnt signaling pathway)|go:""GO:0031267""(small GTPase binding)|go:""GO:0032007""(negative regulation of TOR signaling)|go:""GO:0033596""(TSC1-TSC2 complex)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043276""(anoikis)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0046626""(regulation of insulin receptor signaling pathway)|go:""GO:0046627""(negative regulation of insulin receptor signaling pathway)|go:""GO:0048009""(insulin-like growth factor receptor signaling pathway)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050918""(positive chemotaxis)|go:""GO:0051056""(regulation of small GTPase mediated signal transduction)|go:""GO:0051726""(regulation of cell cycle)|go:""GO:0051879""(Hsp90 protein binding)|go:""GO:0051898""(negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:1901525""(negative regulation of mitophagy)|go:""GO:1904262""(negative regulation of TORC1 signaling)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018515|interpro:IPR024584|interpro:IPR027107|interpro:IPR035974|mint:P49815|rcsb pdb:7DL2|reactome:R-HSA-1632852|reactome:R-HSA-165181|reactome:R-HSA-198323|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-8854214|refseq:NP_000539.2|refseq:NP_001070651.1|refseq:NP_001107854.1|refseq:NP_001305756.1|refseq:NP_001305758.1|refseq:NP_001305760.1|refseq:NP_001305761.1|refseq:XP_005255586.2|refseq:XP_016879105.1|panther:PTHR10063(orthology-group)|ensembl:ENSP00000219476.3|ensembl:ENST00000350773.9|ensembl:ENSP00000344383.4|ensembl:ENST00000382538.10|ensembl:ENSP00000371978.6|ensembl:ENST00000401874.7|ensembl:ENSP00000384468.2|ensembl:ENST00000439673.6|ensembl:ENSP00000399232.2|ensembl:ENST00000642936.1|ensembl:ENSP00000494514.1|ensembl:ENST00000644043.1|ensembl:ENSP00000496262.1"	"interpro:IPR025202|refseq:WP_002211757.1|refseq:NP_395419.1|refseq:YP_094002.1|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|interpro:IPR051406"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:II0K3oybyrXfM4GEYMwV2ZyoWwE9606	rogid:BaOKn4oWF9wcKgOoNSaPk58oQ6k632	intact-crc:2A7FF1D914493CFA|rigid:Nw5G7RANYANLmDxoKajFG0pTspk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B749	uniprotkb:P48995	intact:EBI-2842996|uniprotkb:Q74V98|uniprotkb:Q0WGP3|uniprotkb:Q7CHR5|uniprotkb:A0A384LAC1	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:a0a3n4b749_yerpe(display_long)|uniprotkb:YPO1529(locus name)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851428|imex:IM-13779-5557	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010977(Aromatic-L-amino-acid decarboxylase)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002211877.1|go:""GO:0005737""(cytoplasm)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0016831""(carboxy-lyase activity)|go:""GO:0019752""(carboxylic acid metabolic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:YP_002346545.1|panther:PTHR45677(orthology-group)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Uex6pAvRG3FNG1VCbilPXw5bliY632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:6318864F960F6705|rigid:aXSqiiAzp8lGon0rAaZNS0iVY7A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CK09	uniprotkb:P48995	intact:EBI-2851418|uniprotkb:Q7B0V6|uniprotkb:Q74WP0|uniprotkb:Q0WCG5|uniprotkb:A0A5P8YIG7	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:q7ck09_yerpe(display_long)|uniprotkb:ddhA(gene name)|psi-mi:ddhA(display_short)|uniprotkb:YPO3115(locus name)|uniprotkb:rfbF(gene name synonym)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851415|imex:IM-13779-5556	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR029044|interpro:IPR013446(Glucose-1-phosphate cytidylyltransferase)|interpro:IPR005835(Nucleotidyl transferase)|go:""GO:0009243""(O antigen biosynthetic process)|go:""GO:0047343""(glucose-1-phosphate cytidylyltransferase activity)|refseq:YP_002348023.1|interpro:IPR046981|panther:PTHR47183(orthology-group)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TBBjggvwoVzR1lBlAwLFQUWZ5nk632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:9B9DF9D0A9356938|rigid:cyvEAaGN3n111og6E7oZ/qf8Ww4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48995	uniprotkb:A0A2S9PHG4	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	intact:EBI-2846487|uniprotkb:Q74Y91|uniprotkb:Q7CLC1|uniprotkb:A0A5P8YL17|uniprotkb:A0A0H2W0U8	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	psi-mi:a0a2s9phg4_yerpe(display_long)|uniprotkb:cpxA(gene name)|psi-mi:cpxA(display_short)|uniprotkb:YPO0073(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851396|imex:IM-13779-5555	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|go:""GO:0000155""(phosphorelay sensor kinase activity)|go:""GO:0005886""(plasma membrane)|interpro:IPR032404|interpro:IPR038515|interpro:IPR036097|interpro:IPR036890|refseq:WP_002208971.1|refseq:YP_002345167.1|interpro:IPR050398"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	rogid:g3ZbRmxqWvzTKwK/jxKgrWUTXrU632	intact-crc:5D9FE4DA97CD3F56|rigid:mubQMgAgf3JKPd0IAF3dUGUv4L0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W857	uniprotkb:P48995	intact:EBI-2851403|uniprotkb:Q74PL7|uniprotkb:Q0WAY8|uniprotkb:Q7CL64|uniprotkb:A0A384KWN1	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:a0a0h2w857_yerpe(display_long)|uniprotkb:YPO3664(locus name)|uniprotkb:yhdA(gene name)|psi-mi:yhdA(display_short)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851408|imex:IM-13779-5558	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000160(GGDEF)|interpro:IPR001633(EAL)|interpro:IPR029787|refseq:WP_002210075.1|interpro:IPR033423|go:""GO:0071111""(cyclic-guanylate-specific phosphodiesterase activity)|interpro:IPR043128|interpro:IPR035919|refseq:YP_002348550.1|interpro:IPR050706|panther:PTHR33121(orthology-group)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BGHAMjDoIwj/CmfPvK7qg7wMCig632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:7D37DFECFCFEBC5F|rigid:RC813M2BR7ENVwg/7YWCn0JPNM4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48995	uniprotkb:Q8CZW4	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	intact:EBI-2851384|uniprotkb:Q74QA0	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	psi-mi:q8czw4_yerpe(display_long)|uniprotkb:y3277(locus name)|uniprotkb:fldB(gene name)|psi-mi:fldB(display_short)|uniprotkb:YP_3589(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851389|imex:IM-13779-5559	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"interpro:IPR029039|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001226(Flavodoxin, conserved site)|interpro:IPR010086(Flavodoxin, long chain)|go:""GO:0009055""(electron transfer activity)|go:""GO:0010181""(FMN binding)|interpro:IPR050619"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	rogid:FZlCLDczSf2Gjm4UsIPSSoGJH6E632	intact-crc:97102C2975EB3CDE|rigid:sOfvt8yvq26O8OG210FuJSgeVw8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48995	uniprotkb:A0A2U2GXH7	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	intact:EBI-2848470|uniprotkb:Q74WH6|uniprotkb:Q0WHG3|uniprotkb:A0A0H2W2J4|uniprotkb:Q7CHB5|uniprotkb:A0A384K9G2	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	psi-mi:a0a2u2gxh7_yerpe(display_long)|uniprotkb:YPO1246(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851442|imex:IM-13779-5563	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	interpro:IPR009826(DNA circulation, N-terminal)|refseq:WP_002208852.1|refseq:YP_002346275.1|interpro:IPR052399	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	rogid:Qbi9eC3jfsnnPhDaTUvn+57rY7s632	intact-crc:E906EFFAE19738B3|rigid:3RYc0HOkIEcZ67NkLKpJjAtYwDc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48995	uniprotkb:A0A5P8YCV0	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	intact:EBI-2847775|uniprotkb:Q74Q84|uniprotkb:Q0WIC7|uniprotkb:Q7CGS8|uniprotkb:A0A384L1X8	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	psi-mi:a0a5p8ycv0_yerpe(display_long)|uniprotkb:YPO0913(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851467|imex:IM-13779-5564	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|refseq:WP_002209955.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009396""(folic acid-containing compound biosynthetic process)|go:""GO:0030272""(5-formyltetrahydrofolate cyclo-ligase activity)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|interpro:IPR024185|interpro:IPR037171|refseq:YP_002345961.1|panther:PTHR23407(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	rogid:10+1hunnZ1E8GkdgkFMuY64dDRY632	intact-crc:6806C741EF8FCDE7|rigid:msiQ7GCon/5wmDxntA6xQqDrnus	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PFE9	uniprotkb:P48995	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851460|imex:IM-13779-5562	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:6E6C050DA508CB61|rigid:+C3H5oOQyOuNCfwyU9r5hWzIUJQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GZV9	uniprotkb:P48995	intact:EBI-2851452|uniprotkb:Q74S60|uniprotkb:Q0WHX5|uniprotkb:Q7CH26|uniprotkb:A0A384LQC5	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:a0a2u2gzv9_yerpe(display_long)|uniprotkb:YPO1069(locus name)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851449|imex:IM-13779-5561	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023368|interpro:IPR023370|refseq:WP_002212157.1|go:""GO:0089715""(""tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity"")|interpro:IPR040372|interpro:IPR036413|interpro:IPR036414|interpro:IPR041369|refseq:YP_002346113.1|panther:PTHR12818(orthology-group)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QbU8yYa76G/gWfRLzFass7p1q3Y632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:999C6CCA65436BE7|rigid:Y11xzb6oAo5H1AKEwCQPOg7q+fM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PGH0	uniprotkb:P48995	intact:EBI-2843672|uniprotkb:Q74VD9|uniprotkb:Q7CHN7|uniprotkb:A0A380SBG1|uniprotkb:Q0WGU1	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:a0a2s9pgh0_yerpe(display_long)|uniprotkb:YPO1482(locus name)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851435|imex:IM-13779-5560	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR010623(Protein of unknown function DUF1215)|interpro:IPR009612(ImcF-related)|refseq:WP_002211936.1|interpro:IPR048677|refseq:YP_002346497.1|interpro:IPR053156	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:QiN5WQU27+ZNFJoP65QaVCbJABo632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:0FF66859672E2D9C|rigid:AlPl3fVVmSKADbH0ZC0pBok1kt8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40127	uniprotkb:P48995	intact:EBI-2844091|uniprotkb:Q0WAG2	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:cyaa_yerpe(display_long)|uniprotkb:cya(gene name)|psi-mi:cya(display_short)|uniprotkb:cyaA(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:YPO3848(locus name)|uniprotkb:y0382(locus name)|uniprotkb:YP_3199(locus name)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851511|imex:IM-13779-5569	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000274(Adenylate cyclase, class-I)|interpro:IPR024686|interpro:IPR024685|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006171""(cAMP biosynthetic process)|refseq:WP_002211468.1|refseq:YP_002348726.1|panther:PTHR38760(orthology-group)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l0RzY0/qkJ4UmTdMusK/+DQB0ow632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:CE6B22A4E46938A6|rigid:hADaBnUsLWwtA/1UM7L1lKU1HTE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48995	uniprotkb:A0A3G5LJH8	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	intact:EBI-2851477|uniprotkb:Q74YN1|uniprotkb:Q7ARE0|uniprotkb:Q7BT25|uniprotkb:A0A384KBQ0|uniprotkb:Q65AN4|uniprotkb:A0A1U8QEQ2|uniprotkb:A0A2U2H125|uniprotkb:O68752	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	psi-mi:a0a3g5ljh8_yerpe(display_long)|uniprotkb:YPMT1.34(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851474|imex:IM-13779-5568	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	refseq:NP_395372.1|refseq:YP_093913.1|refseq:NP_857671.1|refseq:WP_002211799.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	rogid:EQfeZsF+Ifz/4ATGhKSB5pDt9HU632	intact-crc:91A182F309036CBE|rigid:VqIDAlzvW/GyX3Mt3dY4iVWRHY4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZEL7	uniprotkb:P48995	intact:EBI-2844441|uniprotkb:Q0WF15	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:dada_yerpe(display_long)|uniprotkb:dadA(gene name)|psi-mi:dadA(display_short)|uniprotkb:YPO2147(locus name)|uniprotkb:y2174(locus name)|uniprotkb:YP_1948(locus name)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851504|imex:IM-13779-5566	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023080|interpro:IPR006076(FAD dependent oxidoreductase)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008718""(D-amino-acid dehydrogenase activity)|go:""GO:0055130""(D-alanine catabolic process)|refseq:WP_002211686.1|interpro:IPR036188|refseq:YP_002347123.1|panther:PTHR13847(orthology-group)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oBXUXNHRC9vQGDI87OKH88hNmMw632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:216E02C07509F6E1|rigid:UGiFTFaJK9C7yyDov1J6q7JHLIE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZBC2	uniprotkb:P48995	intact:EBI-2851492|uniprotkb:Q0WBF3	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:if2_yerpe(display_long)|uniprotkb:infB(gene name)|psi-mi:infB(display_short)|uniprotkb:YPO3496(locus name)|uniprotkb:y0688(locus name)|uniprotkb:YP_0587(locus name)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851497|imex:IM-13779-5567	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002223151.1|interpro:IPR044145|interpro:IPR009061(Putative DNA binding)|interpro:IPR013575(Initiation factor 2 associated region, bacterial)|interpro:IPR006847(Translation initiation factor IF-2, N-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000178(Initiation factor 2)|interpro:IPR023115|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|interpro:IPR015760(Translation initiation factor 2 related)|go:""GO:0003743""(translation initiation factor activity)|go:""GO:0003924""(GTPase activity)|go:""GO:0005525""(GTP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006413""(translational initiation)|go:""GO:0097216""(guanosine tetraphosphate binding)|interpro:IPR036925|interpro:IPR053905|refseq:YP_002348385.1|panther:PTHR43381(orthology-group)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8Lhp4NihTUjn3nGZLA2K6kHbXg8632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:AFA355C0742584EC|rigid:Hpx9miZ1i8Rvj/M5jQwktcj6xWw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CHU1	uniprotkb:P48995	intact:EBI-2841165|uniprotkb:Q74V60	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	psi-mi:mtfa_yerpe(display_long)|uniprotkb:mtfA(gene name)|psi-mi:mtfA(display_short)|uniprotkb:Probable zinc metallopeptidase MtfA(gene name synonym)|uniprotkb:YPO1732(locus name)|uniprotkb:YP_1472(locus name)|uniprotkb:y2576(locus name)	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851485|imex:IM-13779-5565	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002346732.1|interpro:IPR024079|interpro:IPR010384(Protein of unknown function DUF980)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0008237""(metallopeptidase activity)|go:""GO:0008270""(zinc ion binding)|refseq:WP_002211042.1|interpro:IPR042252|panther:PTHR30164(orthology-group)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:3PKDmcLXdDD+p8B4M6novftNc7A632	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	intact-crc:F60F6AD0ABC482CA|rigid:yne2p7VgdqRRkinUXDNr/GHkO9w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C029	uniprotkb:A0A2S9PME1	intact:EBI-2813981|uniprotkb:Q96J90|uniprotkb:Q96F67|uniprotkb:Q969F5|uniprotkb:Q96J89|uniprotkb:A2RUE4|uniprotkb:D3DWR7|ensembl:ENSP00000274773.7	intact:EBI-2851545|uniprotkb:Q74XP7|uniprotkb:A0A0H2W2R8|uniprotkb:Q7CKB3|uniprotkb:A0A384LE92	psi-mi:trim7_human(display_long)|uniprotkb:TRIM7(gene name)|psi-mi:TRIM7(display_short)|uniprotkb:GNIP(gene name synonym)|uniprotkb:RNF90(gene name synonym)|uniprotkb:Glycogenin-interacting protein(gene name synonym)|uniprotkb:RING finger protein 90(gene name synonym)|uniprotkb:Tripartite motif-containing protein 7(gene name synonym)	psi-mi:a0a2s9pme1_yerpe(display_long)|uniprotkb:sgbU(gene name)|psi-mi:sgbU(display_short)|uniprotkb:YPO3333(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851550|imex:IM-13779-5573	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_203128.1|refseq:NP_976038.1|refseq:NP_976039.1|refseq:NP_976040.1|refseq:NP_976041.1|refseq:NP_976042.1|ensembl:ENSG00000146054.18(gene)|ensembl:ENST00000274773.12(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0045087""(innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR043136|interpro:IPR050143|mint:Q9C029|rcsb pdb:6UMA|rcsb pdb:6UMB|rcsb pdb:7OVX|rcsb pdb:7OW2|rcsb pdb:7W0Q|rcsb pdb:7W0S|rcsb pdb:7W0T|rcsb pdb:7X6Y|rcsb pdb:7X6Z|rcsb pdb:7X70|rcsb pdb:7Y3A|rcsb pdb:7Y3B|rcsb pdb:7Y3C|rcsb pdb:8A5L|rcsb pdb:8A5M|rcsb pdb:8A8X|rcsb pdb:8R5B|rcsb pdb:8R5C|rcsb pdb:8R5D|refseq:XP_016865392.1|refseq:XP_016865393.1|panther:PTHR24103(orthology-group)"	"interpro:IPR004560(Putative hexulose-6-phosphate isomerase)|interpro:IPR013022(Xylose isomerase-like, TIM barrel)|refseq:WP_002209420.1|go:""GO:0016861""(intramolecular oxidoreductase activity, interconverting aldoses and ketoses)|go:""GO:0019852""(L-ascorbic acid metabolic process)|go:""GO:0034015""(L-ribulose-5-phosphate 3-epimerase activity)|interpro:IPR036237|refseq:YP_002348229.1|interpro:IPR050417|panther:PTHR43489(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ekxCiH+/bvn81rkv+308lZ2MMdA9606	rogid:W+8J0UnaaqEit6XHmzio9FI6TWA632	intact-crc:F1041B08D6BD2DF0|rigid:/wGmvBGWRvuMCbJZefvoQbWhKB4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15643	uniprotkb:A0A3G5L2Q1	intact:EBI-1047183|uniprotkb:O14689|uniprotkb:O15154|uniprotkb:O95949|uniprotkb:B2RUT2|uniprotkb:Q6MZL5|ensembl:ENSP00000267622.4	intact:EBI-2845751	psi-mi:tripb_human(display_long)|uniprotkb:Golgi-associated microtubule-binding protein 210(gene name synonym)|uniprotkb:Clonal evolution-related gene on chromosome 14 protein(gene name synonym)|uniprotkb:Trip230(gene name synonym)|uniprotkb:TRIP11(gene name)|psi-mi:TRIP11(display_short)|uniprotkb:CEV14(gene name synonym)	psi-mi:a0a3g5l2q1_yerpe(display_long)|uniprotkb:rcsD_1(gene name)|psi-mi:rcsD_1(display_short)|uniprotkb:NCTC5923_01909(orf name)|uniprotkb:y2968(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851525|imex:IM-13779-5571	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100815.12(gene)|ensembl:ENST00000267622.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002079""(inner acrosomal membrane)|go:""GO:0002081""(outer acrosomal membrane)|go:""GO:0003281""(ventricular septum development)|go:""GO:0003413""(chondrocyte differentiation involved in endochondral bone morphogenesis)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005801""(cis-Golgi network)|go:""GO:0005856""(cytoskeleton)|go:""GO:0006366""(transcription by RNA polymerase II)|go:""GO:0006486""(protein glycosylation)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0007030""(Golgi organization)|go:""GO:0030133""(transport vesicle)|go:""GO:0031267""(small GTPase binding)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0051216""(cartilage development)|go:""GO:0060122""(inner ear receptor cell stereocilium organization)|go:""GO:0071806""(protein transmembrane transport)|go:""GO:0090161""(Golgi ribbon formation)|go:""GO:0099041""(vesicle tethering to Golgi)|interpro:IPR000237(GRIP)|mint:Q15643|reactome:R-HSA-5620924|reactome:R-HSA-6811438|reactome:R-HSA-9703465|refseq:NP_004230.2|dip:DIP-40357N|efo:""Orphanet:166272""|efo:""Orphanet:93299""|panther:PTHR18921(orthology-group)"	"uniprotkb:A0A6B3T660(uniprot-removed-ac)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036890|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0016020""(membrane)|go:""GO:0016740""(transferase activity)|refseq:WP_002216093.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:M/XOdT1ZPDaQqMuBXsAB5p6N9LY9606	rogid:r4uXUojxy6U1CFud51vTXRXZz/k632	intact-crc:A61AEF856FD91196|rigid:2YK1sII8SJzKCpWA2xoyOaG/aoI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C029	uniprotkb:A0A2S9PG06	intact:EBI-2813981|uniprotkb:Q96J90|uniprotkb:Q96F67|uniprotkb:Q969F5|uniprotkb:Q96J89|uniprotkb:A2RUE4|uniprotkb:D3DWR7|ensembl:ENSP00000274773.7	intact:EBI-2843697|uniprotkb:Q74RK7|uniprotkb:Q7CGK0|uniprotkb:A0A5P8YJR8|uniprotkb:A0A0H2W6X3	psi-mi:trim7_human(display_long)|uniprotkb:TRIM7(gene name)|psi-mi:TRIM7(display_short)|uniprotkb:GNIP(gene name synonym)|uniprotkb:RNF90(gene name synonym)|uniprotkb:Glycogenin-interacting protein(gene name synonym)|uniprotkb:RING finger protein 90(gene name synonym)|uniprotkb:Tripartite motif-containing protein 7(gene name synonym)	psi-mi:a0a2s9pg06_yerpe(display_long)|uniprotkb:fleR(gene name synonym)|uniprotkb:flbD(gene name)|psi-mi:flbD(display_short)|uniprotkb:YPO0712(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851557|imex:IM-13779-5572	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_203128.1|refseq:NP_976038.1|refseq:NP_976039.1|refseq:NP_976040.1|refseq:NP_976041.1|refseq:NP_976042.1|ensembl:ENSG00000146054.18(gene)|ensembl:ENST00000274773.12(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0045087""(innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR043136|interpro:IPR050143|mint:Q9C029|rcsb pdb:6UMA|rcsb pdb:6UMB|rcsb pdb:7OVX|rcsb pdb:7OW2|rcsb pdb:7W0Q|rcsb pdb:7W0S|rcsb pdb:7W0T|rcsb pdb:7X6Y|rcsb pdb:7X6Z|rcsb pdb:7X70|rcsb pdb:7Y3A|rcsb pdb:7Y3B|rcsb pdb:7Y3C|rcsb pdb:8A5L|rcsb pdb:8A5M|rcsb pdb:8A8X|rcsb pdb:8R5B|rcsb pdb:8R5C|rcsb pdb:8R5D|refseq:XP_016865392.1|refseq:XP_016865393.1|panther:PTHR24103(orthology-group)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|interpro:IPR027417|go:""GO:0000160""(phosphorelay signal transduction system)|go:""GO:0005524""(ATP binding)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0043565""(sequence-specific DNA binding)|refseq:WP_002211445.1|refseq:YP_002345774.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ekxCiH+/bvn81rkv+308lZ2MMdA9606	rogid:MM2YDyuOOazHH+rUpUbNzdJ82sI632	intact-crc:519BC3A39FBF6744|rigid:w1oeoFE2aA97bBXDhcvXiSjT9QU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLD8	uniprotkb:Q9C029	intact:EBI-2851532|uniprotkb:Q74SW5	intact:EBI-2813981|uniprotkb:Q96J90|uniprotkb:Q96F67|uniprotkb:Q969F5|uniprotkb:Q96J89|uniprotkb:A2RUE4|uniprotkb:D3DWR7|ensembl:ENSP00000274773.7	psi-mi:q8cld8_yerpe(display_long)|uniprotkb:icmF2(gene name)|psi-mi:icmF2(display_short)|uniprotkb:YP_2442(locus name)|uniprotkb:y1553(locus name)	psi-mi:trim7_human(display_long)|uniprotkb:TRIM7(gene name)|psi-mi:TRIM7(display_short)|uniprotkb:GNIP(gene name synonym)|uniprotkb:RNF90(gene name synonym)|uniprotkb:Glycogenin-interacting protein(gene name synonym)|uniprotkb:RING finger protein 90(gene name synonym)|uniprotkb:Tripartite motif-containing protein 7(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851538|imex:IM-13779-5574	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010623(Protein of unknown function DUF1215)|interpro:IPR009612(ImcF-related)|interpro:IPR017731(Type VI secretion system, IcmF)|interpro:IPR025743|interpro:IPR027417|go:""GO:0016020""(membrane)|interpro:IPR053156"	"refseq:NP_203128.1|refseq:NP_976038.1|refseq:NP_976039.1|refseq:NP_976040.1|refseq:NP_976041.1|refseq:NP_976042.1|ensembl:ENSG00000146054.18(gene)|ensembl:ENST00000274773.12(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0045087""(innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR043136|interpro:IPR050143|mint:Q9C029|rcsb pdb:6UMA|rcsb pdb:6UMB|rcsb pdb:7OVX|rcsb pdb:7OW2|rcsb pdb:7W0Q|rcsb pdb:7W0S|rcsb pdb:7W0T|rcsb pdb:7X6Y|rcsb pdb:7X6Z|rcsb pdb:7X70|rcsb pdb:7Y3A|rcsb pdb:7Y3B|rcsb pdb:7Y3C|rcsb pdb:8A5L|rcsb pdb:8A5M|rcsb pdb:8A8X|rcsb pdb:8R5B|rcsb pdb:8R5C|rcsb pdb:8R5D|refseq:XP_016865392.1|refseq:XP_016865393.1|panther:PTHR24103(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:w2fthS2L39XGe86y6WdmUYcCZvo632	rogid:ekxCiH+/bvn81rkv+308lZ2MMdA9606	intact-crc:39F1A6CDBF154286|rigid:qsDukJBpqIS1w7GK32H3aXvMO5o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P48995	uniprotkb:Q8ZJ10	intact:EBI-929665|uniprotkb:Q14CE4|ensembl:ENSP00000419313.1	intact:EBI-2845732|uniprotkb:Q0WJY7	psi-mi:trpc1_human(display_long)|uniprotkb:TRPC1(gene name)|psi-mi:TRPC1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:Transient receptor protein 1(gene name synonym)	psi-mi:alr_yerpe(display_long)|uniprotkb:alr(gene name)|psi-mi:alr(display_short)|uniprotkb:YPO0321(locus name)|uniprotkb:YP_0476(locus name)|uniprotkb:y0578(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851518|imex:IM-13779-5570	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003295.1|refseq:NP_001238774.1|ensembl:ENSG00000144935.17(gene)|ensembl:ENST00000476941.6(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005261""(monoatomic cation channel activity)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0015279""(store-operated calcium channel activity)|go:""GO:0034703""(cation channel complex)|go:""GO:0042438""(melanin biosynthetic process)|go:""GO:0043235""(receptor complex)|go:""GO:0044325""(transmembrane transporter binding)|go:""GO:0051117""(ATPase binding)|go:""GO:0051281""(positive regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051480""(regulation of cytosolic calcium ion concentration)|go:""GO:0051592""(response to calcium ion)|go:""GO:0070588""(calcium ion transmembrane transport)|go:""GO:0070679""(inositol 1,4,5 trisphosphate binding)|go:""GO:1903779""(regulation of cardiac conduction)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005457(Transient receptor potential channel 1)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:8WPL|rcsb pdb:8WPM|reactome:R-HSA-3295583|reactome:R-HSA-418890|reactome:R-HSA-5578775|reactome:R-HSA-983695|dip:DIP-35698N|panther:PTHR10117(orthology-group)"	"interpro:IPR000821(Alanine racemase region)|interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR011079(Alanine racemase, C-terminal)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR020622|interpro:IPR029066|refseq:WP_002209096.1|go:""GO:0005829""(cytosol)|go:""GO:0008784""(alanine racemase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0030632""(D-alanine biosynthetic process)|refseq:YP_002345401.1|panther:PTHR30511(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:H+7DrzEcXydnh0OjQAw0KsLLxMs9606	rogid:DHbxD7IyYyhVi917Zw+/1ybH+hI632	intact-crc:9AFADDC0748E312E|rigid:ufg7DtiUM5NuZ5eC8jWKq8qHUJ0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9C029	uniprotkb:Q8ZIK3	intact:EBI-2813981|uniprotkb:Q96J90|uniprotkb:Q96F67|uniprotkb:Q969F5|uniprotkb:Q96J89|uniprotkb:A2RUE4|uniprotkb:D3DWR7|ensembl:ENSP00000274773.7	intact:EBI-2851567|uniprotkb:Q0WJH0	psi-mi:trim7_human(display_long)|uniprotkb:TRIM7(gene name)|psi-mi:TRIM7(display_short)|uniprotkb:GNIP(gene name synonym)|uniprotkb:RNF90(gene name synonym)|uniprotkb:Glycogenin-interacting protein(gene name synonym)|uniprotkb:RING finger protein 90(gene name synonym)|uniprotkb:Tripartite motif-containing protein 7(gene name synonym)	psi-mi:lptd_yerpe(display_long)|uniprotkb:lptD(gene name)|psi-mi:lptD(display_short)|uniprotkb:imp(gene name synonym)|uniprotkb:ostA(gene name synonym)|uniprotkb:YPO0495(locus name)|uniprotkb:y3680(locus name)|uniprotkb:YP_3684(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851564|imex:IM-13779-5575	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_203128.1|refseq:NP_976038.1|refseq:NP_976039.1|refseq:NP_976040.1|refseq:NP_976041.1|refseq:NP_976042.1|ensembl:ENSG00000146054.18(gene)|ensembl:ENST00000274773.12(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0045087""(innate immune response)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR043136|interpro:IPR050143|mint:Q9C029|rcsb pdb:6UMA|rcsb pdb:6UMB|rcsb pdb:7OVX|rcsb pdb:7OW2|rcsb pdb:7W0Q|rcsb pdb:7W0S|rcsb pdb:7W0T|rcsb pdb:7X6Y|rcsb pdb:7X6Z|rcsb pdb:7X70|rcsb pdb:7Y3A|rcsb pdb:7Y3B|rcsb pdb:7Y3C|rcsb pdb:8A5L|rcsb pdb:8A5M|rcsb pdb:8A8X|rcsb pdb:8R5B|rcsb pdb:8R5C|rcsb pdb:8R5D|refseq:XP_016865392.1|refseq:XP_016865393.1|panther:PTHR24103(orthology-group)"	"refseq:WP_002228111.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0015920""(lipopolysaccharide transport)|go:""GO:0043165""(Gram-negative-bacterium-type cell outer membrane assembly)|go:""GO:1990351""(transporter complex)|interpro:IPR005653(OstA-like protein)|interpro:IPR007543(Organic solvent tolerance protein)|interpro:IPR020889|interpro:IPR050218|rcsb pdb:5IXM|dip:DIP-62066N|refseq:YP_002345568.1|panther:PTHR30189(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ekxCiH+/bvn81rkv+308lZ2MMdA9606	rogid:dvAas4Q1yxSAV+PBwvS2+Zl7YVI632	intact-crc:8FDDF224BD14C8E9|rigid:j4bPDrs0L7XxQDJhk0ZtVNsUo4U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PFE9	uniprotkb:Q6PJ69	intact:EBI-2839958|uniprotkb:A0A384LGT3|uniprotkb:Q74Q86|uniprotkb:A0A0H2W895|uniprotkb:Q7CGS9	intact:EBI-2130441|ensembl:ENSP00000269383.3|uniprotkb:Q4G0F0|uniprotkb:Q6DKJ6|uniprotkb:Q9BRP6	psi-mi:a0a2s9pfe9_yerpe(display_long)|uniprotkb:pepP(gene name)|psi-mi:pepP(display_short)|uniprotkb:YPO0910(locus name)	psi-mi:tri65_human(display_long)|uniprotkb:TRIM65(gene name)|psi-mi:TRIM65(display_short)|uniprotkb:Tripartite motif-containing protein 65(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851583|imex:IM-13779-5579	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P  N-terminal)|refseq:YP_002345958.1|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|go:""GO:0004177""(aminopeptidase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006508""(proteolysis)|go:""GO:0030145""(manganese ion binding)|go:""GO:0070006""(metalloaminopeptidase activity)|interpro:IPR052433|interpro:IPR029149|rcsb pdb:4PV4|refseq:WP_002209952.1|interpro:IPR036005|panther:PTHR43226(orthology-group)"	"ensembl:ENSG00000141569.12(gene)|ensembl:ENST00000269383.8(transcript)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0032461""(positive regulation of protein oligomerization)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0140374""(antiviral innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|interpro:IPR048222|interpro:IPR051051|mint:Q6PJ69|rcsb pdb:7JL0|rcsb pdb:7JL2|rcsb pdb:7JL4|refseq:NP_775818.2|refseq:NP_001243053.1|panther:PTHR25465(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:038c6EygZ+qtq8nW7WIAgL1J9R8632	rogid:oV3SxWrEWzpj3c5ljfkAOU98XuY9606	intact-crc:009E6CAF7981A490|rigid:TZRfd09JrRzri6u9xYywiJ+xVsc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YJ27	uniprotkb:Q96LD4	intact:EBI-2841490	intact:EBI-2130423|ensembl:ENSP00000254816.1|uniprotkb:Q96GU5|uniprotkb:Q9BRN7|uniprotkb:Q96AD0|intact:EBI-28987808	psi-mi:a0a5p8yj27_yerpe(display_long)|uniprotkb:citT3(gene name)|psi-mi:citT3(display_short)|uniprotkb:YP_3442(locus name)|uniprotkb:y3435(locus name)	psi-mi:tri47_human(display_long)|uniprotkb:TRIM47(gene name)|psi-mi:TRIM47(display_short)|uniprotkb:GOA(gene name synonym)|uniprotkb:RNF100(gene name synonym)|uniprotkb:Gene overexpressed in astrocytoma protein(gene name synonym)|uniprotkb:RING finger protein 100(gene name synonym)|uniprotkb:Tripartite motif-containing protein 47(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851597|imex:IM-13779-5577	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001898(Sodium/sulphate symporter)|interpro:IPR031312|refseq:WP_002223680.1|uniprotkb:A0A0H2W955(uniprot-removed-ac)|go:""GO:0016020""(membrane)|go:""GO:0022857""(transmembrane transporter activity)"	"ensembl:ENSG00000132481.7(gene)|ensembl:ENST00000254816.6(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0150052""(regulation of postsynapse assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR042780|interpro:IPR043136|interpro:IPR051051|mint:Q96LD4|refseq:NP_258411.2|refseq:XP_005257844.1|refseq:XP_005257845.1|panther:PTHR25465(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VfX27LYp7fbCscbJTQp3/YxQw3Y632	rogid:F8KSNivuNkLAEFW/DrYsMu5ICRk9606	intact-crc:B439A851DC89A3D8|rigid:BO5sTawBHjvKWy7VHPC1wJBMbko	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75382	uniprotkb:A0A384KHP8	intact:EBI-2129889|uniprotkb:Q4V9L4|uniprotkb:Q9C038|uniprotkb:Q9C039|uniprotkb:B7Z5E6|uniprotkb:F5H2Q8|ensembl:ENSP00000340797.3|ensembl:ENSP00000352508.3|ensembl:ENSP00000433102.1	intact:EBI-2840740|uniprotkb:Q74S58|uniprotkb:Q0WHX7|uniprotkb:Q7CH24	psi-mi:trim3_human(display_long)|uniprotkb:TRIM3(gene name)|psi-mi:TRIM3(display_short)|uniprotkb:BERP(gene name synonym)|uniprotkb:RNF22(gene name synonym)|uniprotkb:RNF97(gene name synonym)|uniprotkb:RING finger protein 22(gene name synonym)|uniprotkb:Brain-expressed RING finger protein(gene name synonym)|uniprotkb:RING finger protein 97(gene name synonym)	psi-mi:a0a384khp8_yerpe(display_long)|uniprotkb:cutF(gene name)|psi-mi:cutF(display_short)|uniprotkb:nlpE(gene name synonym)|uniprotkb:YPO1067(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851576|imex:IM-13779-5576	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011518146.1|refseq:XP_011518147.1|refseq:NP_006449.2|refseq:NP_150594.2|refseq:NP_001234935.1|refseq:NP_001234936.1|refseq:XP_016872587.1|refseq:XP_016872588.1|ensembl:ENSG00000110171.21(gene)|ensembl:ENST00000345851.8(transcript)|ensembl:ENST00000359518.7(transcript)|ensembl:ENST00000525074.5(transcript)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0007399""(nervous system development)|go:""GO:0008270""(zinc ion binding)|go:""GO:0015031""(protein transport)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0030371""(translation repressor activity)|go:""GO:0030425""(dendrite)|go:""GO:0034141""(positive regulation of toll-like receptor 3 signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0061351""(neural precursor cell proliferation)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR018957|interpro:IPR050952|mint:O75382|rcsb pdb:7O0B|rcsb pdb:7QRW|rcsb pdb:8AMR|reactome:R-HSA-877300|panther:PTHR24104(orthology-group)"	interpro:IPR007298(Copper resistance lipoprotein NlpE)|interpro:IPR033450|interpro:IPR038139|interpro:IPR043176|refseq:YP_002346111.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Vz2XqDSJXAWxxubxtghV91m9K009606	rogid:ryLPtdXQoNwxiqxUzYaySoAkJkc632	intact-crc:D6EB12142B52A93B|rigid:4HawrhrYoRKqqFzK//3W63NH5GA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BRZ2	uniprotkb:Q9F286	intact:EBI-1048636|uniprotkb:Q6PJS5|uniprotkb:Q86VT6|uniprotkb:Q8N2H8|uniprotkb:Q8NAC0|uniprotkb:Q9H031|intact:EBI-2129929|ensembl:ENSP00000305161.6	intact:EBI-2841010|uniprotkb:Q7CGD1|uniprotkb:A0A1U8QV59|uniprotkb:A0A3N4B736	psi-mi:tri56_human(display_long)|uniprotkb:RING finger protein 109(gene name synonym)|uniprotkb:TRIM56(gene name)|psi-mi:TRIM56(display_short)|uniprotkb:RNF109(gene name synonym)|uniprotkb:Tripartite motif-containing protein 56(gene name synonym)	psi-mi:q9f286_yerpe(display_long)|uniprotkb:yapG(gene name)|psi-mi:yapG(display_short)|uniprotkb:YPO0587(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851590|imex:IM-13779-5578	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_112223.1|ensembl:ENSG00000169871.13(gene)|ensembl:ENST00000306085.11(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0008270""(zinc ion binding)|go:""GO:0032479""(regulation of type I interferon production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0034340""(response to type I interferon)|go:""GO:0045087""(innate immune response)|go:""GO:0045089""(positive regulation of innate immune response)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR047153|rcsb pdb:5JW7|reactome:R-HSA-3134975|refseq:XP_011514891.1|panther:PTHR25462(orthology-group)"	"interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR043990|go:""GO:0019867""(outer membrane)|refseq:YP_002345659.1|refseq:WP_002210403.1|interpro:IPR036709|interpro:IPR050909|panther:PTHR12338(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ezli6d8R3mc5aNovKvPv2ayypbE9606	rogid:2Mt4+cjY2sa9LFUy2Ed940D/w7I632	intact-crc:1C96FC747899E01E|rigid:A5/CqHMlJ3I/fSu9Q4K2qy7ELig	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YGB7	uniprotkb:Q8IYM9	intact:EBI-2840543|uniprotkb:Q74TG4|uniprotkb:A0A0H2W5B5|uniprotkb:Q7CIT3	intact:EBI-954123|uniprotkb:Q15521|uniprotkb:Q05CQ0|ensembl:ENSP00000369299.3	psi-mi:a0a5p8ygb7_yerpe(display_long)|uniprotkb:YPO2407(locus name)	psi-mi:tri22_human(display_long)|uniprotkb:RING finger protein 94(gene name synonym)|uniprotkb:50 kDa-stimulated trans-acting factor(gene name synonym)|uniprotkb:Staf-50(gene name synonym)|uniprotkb:Tripartite motif-containing protein 22(gene name synonym)|uniprotkb:TRIM22(gene name)|psi-mi:TRIM22(display_short)|uniprotkb:RNF94(gene name synonym)|uniprotkb:STAF50(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM22(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851637|imex:IM-13779-5582	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR017900|interpro:IPR017896|go:""GO:0004458""(""D-lactate dehydrogenase (cytochrome) activity"")|go:""GO:0008720""(D-lactate dehydrogenase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0050660""(flavin adenine dinucleotide binding)|go:""GO:0051536""(iron-sulfur cluster binding)|go:""GO:0071949""(FAD binding)|go:""GO:1903457""(lactate catabolic process)|refseq:WP_002211811.1|refseq:YP_002347372.1|interpro:IPR036318|panther:PTHR11748(orthology-group)"	"refseq:NP_001186502.1|refseq:NP_006065.2|ensembl:ENSG00000132274.17(gene)|ensembl:ENST00000379965.8(transcript)|go:""GO:0002230""(positive regulation of defense response to virus by host)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003714""(transcription corepressor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0006955""(immune response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009615""(response to virus)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010508""(positive regulation of autophagy)|go:""GO:0015030""(Cajal body)|go:""GO:0016604""(nuclear body)|go:""GO:0016607""(nuclear speck)|go:""GO:0019901""(protein kinase binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0042802""(identical protein binding)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045087""(innate immune response)|go:""GO:0046596""(regulation of viral entry into host cell)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051607""(defense response to virus)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070534""(protein K63-linked ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR035827|interpro:IPR043136|interpro:IPR050143|mint:Q8IYM9|reactome:R-HSA-877300|panther:PTHR24103(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+AKaGlzVLFzyk6qOAb7Vy0Ex+6o632	rogid:8CNTleevg3ll6+eu/3p28ysv1M09606	intact-crc:A46C59337F9A6C50|rigid:jCSBre4fIq7UMf6WeiQ90fWxXeY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYH3	uniprotkb:Q8WV44	intact:EBI-2842340|uniprotkb:Q74PE3|uniprotkb:Q0W9X2|uniprotkb:Q7CFQ3|uniprotkb:A0A5P8YAI4|uniprotkb:A0A384L096	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869.5	psi-mi:a0a2u2gyh3_yerpe(display_long)|uniprotkb:fdoH(gene name)|psi-mi:fdoH(display_short)|uniprotkb:YPO4057(locus name)	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851611|imex:IM-13779-5581	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR017896|interpro:IPR006470(Formate dehydrogenase, beta subunit)|interpro:IPR014603(Formate dehydrogenase, iron-sulphur subunit)|interpro:IPR015246(Formate dehydrogenase, transmembrane)|interpro:IPR017900|go:""GO:0005886""(plasma membrane)|go:""GO:0015944""(formate oxidation)|go:""GO:0045333""(cellular respiration)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|refseq:WP_002209611.1|interpro:IPR038384|refseq:YP_002348916.1|interpro:IPR051555"	"refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063.20(gene)|ensembl:ENST00000315073.10(transcript)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016604""(nuclear body)|go:""GO:0042802""(identical protein binding)|go:""GO:0045087""(innate immune response)|go:""GO:0051607""(defense response to virus)|go:""GO:0060340""(positive regulation of type I interferon-mediated signaling pathway)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071225""(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|interpro:IPR050143|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168|panther:PTHR24103(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qUnsGukyBMEHq2jL5PYOvQ0betE632	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	intact-crc:E75806833ACDA36A|rigid:7zFms0buIGWu8nOwcSz8nCmk2tk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0D4	uniprotkb:Q14258	intact:EBI-2847212	intact:EBI-2341129|ensembl:ENSP00000323889.4|ensembl:ENSP00000445961.1|intact:EBI-28973868	psi-mi:q8d0d4_yerpe(display_long)|uniprotkb:hmsH(gene name)|psi-mi:hmsH(display_short)|uniprotkb:y2359(locus name)	psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851630|imex:IM-13779-5583	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023870|interpro:IPR011990(Tetratricopeptide-like helical)|go:""GO:1901515""(poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity)|interpro:IPR049003"	"ensembl:ENSG00000121060.19(gene)|ensembl:ENST00000316881.9(transcript)|ensembl:ENST00000537230.3(transcript)|go:""GO:0002753""(cytoplasmic pattern recognition receptor signaling pathway)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0016604""(nuclear body)|go:""GO:0016874""(ligase activity)|go:""GO:0019076""(viral release from host cell)|go:""GO:0032880""(regulation of protein localization)|go:""GO:0033280""(response to vitamin D)|go:""GO:0036503""(ERAD pathway)|go:""GO:0039552""(RIG-I binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043627""(response to estrogen)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0045087""(innate immune response)|go:""GO:0045296""(cadherin binding)|go:""GO:0046596""(regulation of viral entry into host cell)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046872""(metal ion binding)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0140374""(antiviral innate immune response)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR042753|interpro:IPR043136|interpro:IPR051051|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|reactome:R-HSA-9692916|reactome:R-HSA-9705671|reactome:R-HSA-9833109|reactome:R-HSA-9833110|reactome:R-HSA-9833482|refseq:NP_005073.2|panther:PTHR25465(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oBs/IRM9/gKecuXNw9IoCZLu4Vw632	rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606	intact-crc:F5CB0496791A7C46|rigid:U+ca33L5F2TCnEB4XT8GFL70G2A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96LD4	uniprotkb:A0A2S9PKW4	intact:EBI-2130423|ensembl:ENSP00000254816.1|uniprotkb:Q96GU5|uniprotkb:Q9BRN7|uniprotkb:Q96AD0|intact:EBI-28987808	intact:EBI-2849768|uniprotkb:Q74WE2|uniprotkb:A0A5P8YE16|uniprotkb:Q7CH90|uniprotkb:A0A0H2W1N2	psi-mi:tri47_human(display_long)|uniprotkb:TRIM47(gene name)|psi-mi:TRIM47(display_short)|uniprotkb:GOA(gene name synonym)|uniprotkb:RNF100(gene name synonym)|uniprotkb:Gene overexpressed in astrocytoma protein(gene name synonym)|uniprotkb:RING finger protein 100(gene name synonym)|uniprotkb:Tripartite motif-containing protein 47(gene name synonym)	psi-mi:a0a2s9pkw4_yerpe(display_long)|uniprotkb:dinG(gene name)|psi-mi:dinG(display_short)|uniprotkb:DNA 5'-3' helicase DinG(gene name synonym)|uniprotkb:rarB(gene name synonym)|uniprotkb:YPO1206(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851604|imex:IM-13779-5580	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000132481.7(gene)|ensembl:ENST00000254816.6(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0098794""(postsynapse)|go:""GO:0098978""(glutamatergic synapse)|go:""GO:0150052""(regulation of postsynapse assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR042780|interpro:IPR043136|interpro:IPR051051|mint:Q96LD4|refseq:NP_258411.2|refseq:XP_005257844.1|refseq:XP_005257845.1|panther:PTHR25465(orthology-group)"	"interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR010614(DEAD2)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR027417|refseq:WP_002210810.1|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0006139""(nucleobase-containing compound metabolic process)|go:""GO:0016818""(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:""GO:0016853""(isomerase activity)|go:""GO:0043139""(5'-3' DNA helicase activity)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR039000|refseq:YP_002346240.1|interpro:IPR045028"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:F8KSNivuNkLAEFW/DrYsMu5ICRk9606	rogid:Pz/QYhpy8rsVBaUUTk559v1mAL4632	intact-crc:D43F1D2456375E66|rigid:6cukuOKjIrrBy8hechMhFy0jS1o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94972	uniprotkb:P58526	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6|ensembl:ENSP00000262294.7|ensembl:ENSP00000376785.3	intact:EBI-2851618|uniprotkb:Q0WE76	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:mtox_yerpe(display_long)|uniprotkb:solA(gene name)|psi-mi:solA(display_short)|uniprotkb:YPO2448(locus name)|uniprotkb:y1742(locus name)|uniprotkb:YP_2268(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851623|imex:IM-13779-5584	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000108395.14(gene)|ensembl:ENST00000262294.12(transcript)|ensembl:ENST00000393066.7(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0003682""(chromatin binding)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005694""(chromosome)|go:""GO:0005737""(cytoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005778""(peroxisomal membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0008270""(zinc ion binding)|go:""GO:0016235""(aggresome)|go:""GO:0016558""(protein import into peroxisome matrix)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0035098""(""ESC/E(Z) complex"")|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0045814""(negative regulation of gene expression, epigenetic)|go:""GO:0046600""(negative regulation of centriole replication)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0050821""(protein stabilization)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070842""(aggresome assembly)|go:""GO:0140862""(histone H2AK119 ubiquitin ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|interpro:IPR053003|mint:O94972|rcsb pdb:3LRQ|reactome:R-HSA-983168|refseq:NP_001005207.1|refseq:NP_001307916.1|refseq:NP_001307919.1|refseq:NP_056109.1|dip:DIP-34437N|efo:""Orphanet:2576""|panther:PTHR36754(orthology-group)"	"interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR023493|refseq:WP_002211850.1|go:""GO:0005829""(cytosol)|go:""GO:0008115""(sarcosine oxidase activity)|go:""GO:0050131""(N-methyl-L-amino-acid oxidase activity)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|refseq:YP_002347412.1|interpro:IPR045170|panther:PTHR10961(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:CVPINp8wGJnyzKPXSUk8Tm4az0w632	intact-crc:600350A152504DB3|rigid:WDbpMBgtmVBlJPFS0NKzFMZOoVE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O60296	uniprotkb:Q7ARD3	intact:EBI-2851680|uniprotkb:Q9C0K6|uniprotkb:Q8WVH7|uniprotkb:Q96NS2|uniprotkb:Q9C0K5|uniprotkb:E7EV21|ensembl:ENSP00000328875.3	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:trak2_human(display_long)|uniprotkb:TRAK2(gene name)|psi-mi:TRAK2(display_short)|uniprotkb:ALS2CR3(gene name synonym)|uniprotkb:KIAA0549(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851688|imex:IM-13779-5587	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011509992.1|refseq:NP_055864.2|ensembl:ENSG00000115993.13(gene)|ensembl:ENST00000332624.8(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005769""(early endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006605""(protein targeting)|go:""GO:0017022""(myosin binding)|go:""GO:0022008""(neurogenesis)|go:""GO:0030425""(dendrite)|go:""GO:0031410""(cytoplasmic vesicle)|go:""GO:0047496""(vesicle transport along microtubule)|go:""GO:0048311""(mitochondrion distribution)|go:""GO:0050811""(GABA receptor binding)|go:""GO:0098957""(anterograde axonal transport of mitochondrion)|go:""GO:1904115""(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|interpro:IPR051946|mint:O60296|reactome:R-HSA-9013419|reactome:R-HSA-9013425|panther:PTHR15751(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aBkA/J62vwLCHbYqkaXOE4rbaZ89606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:47662DDC5D6FA224|rigid:ygeS6thj0tVrJte9OYPwjjohQes	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0R7	uniprotkb:P02788	intact:EBI-2851663	intact:EBI-1058602|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|ensembl:ENSP00000231751.4|uniprotkb:A8K9U8	psi-mi:q8d0r7_yerpe(display_long)|uniprotkb:y1701(locus name)	psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851666|imex:IM-13779-5589	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006914(Protein of unknown function DUF638, haemagglutinin/haemolysin putative)|go:""GO:0090729""(toxin activity)"	"refseq:NP_001308050.1|refseq:NP_001186078.1|refseq:NP_002334.2|ensembl:ENSG00000012223.13(gene)|ensembl:ENST00000231751.9(transcript)|go:""GO:0001503""(ossification)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002227""(innate immune response in mucosa)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0004869""(cysteine-type endopeptidase inhibitor activity)|go:""GO:0005506""(iron ion binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0006826""(iron ion transport)|go:""GO:0006959""(humoral immune response)|go:""GO:0008201""(heparin binding)|go:""GO:0009986""(cell surface)|go:""GO:0019731""(antibacterial humoral response)|go:""GO:0019732""(antifungal humoral response)|go:""GO:0030141""(secretory granule)|go:""GO:0031640""(killing of cells of another organism)|go:""GO:0031665""(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:""GO:0032680""(regulation of tumor necrosis factor production)|go:""GO:0032780""(negative regulation of ATP-dependent activity)|go:""GO:0032991""(protein-containing complex)|go:""GO:0033690""(positive regulation of osteoblast proliferation)|go:""GO:0034145""(positive regulation of toll-like receptor 4 signaling pathway)|go:""GO:0035580""(specific granule lumen)|go:""GO:0042581""(specific granule)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044793""(negative regulation by host of viral process)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045669""(positive regulation of osteoblast differentiation)|go:""GO:0048525""(negative regulation of viral process)|rcsb pdb:1H45|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0055037""(recycling endosome)|go:""GO:0060349""(bone morphogenesis)|go:""GO:0061844""(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071902""(positive regulation of protein serine/threonine kinase activity)|go:""GO:0097013""(phagocytic vesicle lumen)|go:""GO:0140912""(membrane destabilizing activity)|go:""GO:1900159""(positive regulation of bone mineralization involved in bone maturation)|go:""GO:1900229""(negative regulation of single-species biofilm formation in or on host organism)|go:""GO:1902732""(positive regulation of chondrocyte proliferation)|go:""GO:1904724""(tertiary granule lumen)|go:""GO:2000117""(obsolete negative regulation of cysteine-type endopeptidase activity)|go:""GO:2000308""(""negative regulation of tumor necrosis factor (ligand) superfamily member 11 production"")|go:""GO:2001205""(negative regulation of osteoclast development)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1U62|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|rcsb pdb:7JRD|rcsb pdb:7N88|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|refseq:NP_001308051.1|dip:DIP-41354N|panther:PTHR11485(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/19	rogid:Ks3lO/T2b4EUIIi1eSL1nvjMQjw632	rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606	intact-crc:4D138437CDDD2211|rigid:j6PimNYwUS2sPd4WUeNeo3/h3eg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q96F44	uniprotkb:Q8ZJM6	intact:EBI-851809|uniprotkb:B2RB82|uniprotkb:B3KUS3|uniprotkb:B4DX88|uniprotkb:Q8NCA6|uniprotkb:Q9C022|uniprotkb:A6NKE2|uniprotkb:Q5VSU1|ensembl:ENSP00000284551.6	intact:EBI-2851651|uniprotkb:Q0WKM6	psi-mi:tri11_human(display_long)|uniprotkb:RING finger protein 92(gene name synonym)|uniprotkb:Protein BIA1(gene name synonym)|uniprotkb:TRIM11(gene name)|psi-mi:TRIM11(display_short)|uniprotkb:RNF92(gene name synonym)|uniprotkb:Tripartite motif-containing protein 11(gene name synonym)	"psi-mi:gpda_yerpe(display_long)|uniprotkb:gpsA(gene name)|psi-mi:gpsA(display_short)|uniprotkb:""NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase""(gene name synonym)|uniprotkb:""NAD(P)H-dependent dihydroxyacetone-phosphate reductase""(gene name synonym)|uniprotkb:YPO0068(locus name)|uniprotkb:YP_0068(locus name)|uniprotkb:y0073(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851656|imex:IM-13779-5586	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_660215.1|refseq:XP_016857901.1|panther:PTHR24103(orthology-group)|ensembl:ENSG00000154370.16(gene)|ensembl:ENST00000284551.11(transcript)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0016567""(protein ubiquitination)|go:""GO:0019904""(protein domain specific binding)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0044790""(suppression of viral release by host)|go:""GO:0045087""(innate immune response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0046597""(host-mediated suppression of symbiont invasion)|go:""GO:0046598""(positive regulation of viral entry into host cell)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|go:""GO:0050768""(negative regulation of neurogenesis)|go:""GO:0051865""(protein autoubiquitination)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0140972""(negative regulation of AIM2 inflammasome complex assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR043136|interpro:IPR050143|mint:Q96F44|rcsb pdb:7QS1|reactome:R-HSA-983168"	"interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|go:""GO:0005829""(cytosol)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0006072""(glycerol-3-phosphate metabolic process)|go:""GO:0046167""(glycerol-3-phosphate biosynthetic process)|go:""GO:0046168""(glycerol-3-phosphate catabolic process)|go:""GO:0046474""(glycerophospholipid biosynthetic process)|go:""GO:0047952""(""glycerol-3-phosphate dehydrogenase [NAD(P)+] activity"")|go:""GO:0051287""(NAD binding)|interpro:IPR036291|refseq:WP_002208975.1|refseq:YP_002345162.1|panther:PTHR11728(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:cE4Lcnp0zSSEpo3e9Kr940Vdit89606	rogid:2hm6gX1va61mqUN0MQ33b3wJY38632	intact-crc:FBFBC31DFAC58C94|rigid:TSi45q5u4OMQcVa4sgoxBKqz/Sw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P07204	uniprotkb:Q8ZEL7	intact:EBI-941422|uniprotkb:Q8IV29|uniprotkb:Q9UC32|ensembl:ENSP00000366307.2	intact:EBI-2844441|uniprotkb:Q0WF15	psi-mi:trbm_human(display_long)|uniprotkb:THBD(gene name)|psi-mi:THBD(display_short)|uniprotkb:THRM(gene name synonym)|uniprotkb:Fetomodulin(gene name synonym)	psi-mi:dada_yerpe(display_long)|uniprotkb:dadA(gene name)|psi-mi:dadA(display_short)|uniprotkb:YPO2147(locus name)|uniprotkb:y2174(locus name)|uniprotkb:YP_1948(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851673|imex:IM-13779-5588	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000178726.7(gene)|ensembl:ENST00000377103.3(transcript)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005774""(vacuolar membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006508""(proteolysis)|go:""GO:0007565""(female pregnancy)|go:""GO:0007596""(blood coagulation)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010165""(response to X-ray)|go:""GO:0010544""(negative regulation of platelet activation)|go:""GO:0016327""(apicolateral plasma membrane)|go:""GO:0030195""(negative regulation of blood coagulation)|go:""GO:0031638""(zymogen activation)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0051591""(response to cAMP)|go:""GO:0051918""(negative regulation of fibrinolysis)|go:""GO:0072377""(blood coagulation, common pathway)|go:""GO:1905370""(serine-type endopeptidase complex)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001304(C-type lectin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR015149(Thrombomodulin-like, EGF-like)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018097|interpro:IPR026823|interpro:IPR049883|interpro:IPR052126|rcsb pdb:1ADX|rcsb pdb:1DQB|rcsb pdb:1DX5|rcsb pdb:1EGT|rcsb pdb:1FGD|rcsb pdb:1FGE|rcsb pdb:1HLT|rcsb pdb:1TMR|rcsb pdb:1ZAQ|rcsb pdb:2ADX|rcsb pdb:3GIS|rcsb pdb:5TO3|rcsb pdb:7T4R|reactome:R-HSA-140875|reactome:R-HSA-202733|refseq:NP_000352.1|efo:""Orphanet:436169""|efo:""Orphanet:544472""|panther:PTHR24036(orthology-group)"	"interpro:IPR023080|interpro:IPR006076(FAD dependent oxidoreductase)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008718""(D-amino-acid dehydrogenase activity)|go:""GO:0055130""(D-alanine catabolic process)|refseq:WP_002211686.1|interpro:IPR036188|refseq:YP_002347123.1|panther:PTHR13847(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6plk9lmL2aEGHQfdwj/wXLkAocg9606	rogid:oBXUXNHRC9vQGDI87OKH88hNmMw632	intact-crc:E13A2EB65BAAF364|rigid:4b2nZ6HkEhAU+UKV3m3GSc2/kwY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q14142	uniprotkb:Q7CJF3	intact:EBI-2820256|uniprotkb:Q9BRD8|uniprotkb:A8K9W0|uniprotkb:Q9C020|uniprotkb:Q5TBQ8|uniprotkb:E7EQC4|uniprotkb:F8W956|uniprotkb:Q548W9|uniprotkb:Q6ZWL7|ensembl:ENSP00000343990.3|ensembl:ENSP00000344208.2|ensembl:ENSP00000364239.3	intact:EBI-2846856|uniprotkb:Q74SI9	psi-mi:tri14_human(display_long)|uniprotkb:TRIM14(gene name)|psi-mi:TRIM14(display_short)|uniprotkb:KIAA0129(gene name synonym)	"psi-mi:dnlj_yerpe(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:""Polydeoxyribonucleotide synthase [NAD(+)]""(gene name synonym)|uniprotkb:YPO2989(locus name)|uniprotkb:YP_2614(locus name)|uniprotkb:y1492(locus name)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851644|imex:IM-13779-5585	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055603.2|refseq:NP_150088.1|refseq:XP_005252377.1|ensembl:ENSG00000106785.15(gene)|ensembl:ENST00000341469.7(transcript)|ensembl:ENST00000342043.3(transcript)|ensembl:ENST00000375098.7(transcript)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005741""(mitochondrial outer membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0008270""(zinc ion binding)|go:""GO:0032897""(negative regulation of viral transcription)|go:""GO:0045087""(innate immune response)|go:""GO:0045335""(phagocytic vesicle)|go:""GO:0051091""(positive regulation of DNA-binding transcription factor activity)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061630""(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001870(""B302 (SPRY)-like"")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|interpro:IPR044116|interpro:IPR051051|rcsb pdb:6JBM|reactome:R-HSA-877300|refseq:XP_016870842.1|refseq:XP_016870841.1|panther:PTHR24103(orthology-group)"	"interpro:IPR033136|interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR004149(Zinc-finger, NAD-dependent DNA ligase C4-type)|refseq:WP_002213368.1|go:""GO:0003677""(DNA binding)|go:""GO:0003911""(""DNA ligase (NAD+) activity"")|go:""GO:0005829""(cytosol)|go:""GO:0006260""(DNA replication)|go:""GO:0006288""(obsolete base-excision repair, DNA ligation)|go:""GO:0046872""(metal ion binding)|interpro:IPR036420|interpro:IPR041663|refseq:YP_002347913.1|panther:PTHR23389(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ipI5FqULkzJ3X75w+PHiO3DmcNk9606	rogid:ABzJi1jMOUD1WGHNwTu2zo0ozls632	intact-crc:57BC36F73FD1CB9B|rigid:RQRJgwIl4K/iTTA1GtC/twUKEW4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0L3	uniprotkb:Q13114	intact:EBI-2851698|uniprotkb:Q74TK2	intact:EBI-357631|uniprotkb:Q12990|uniprotkb:Q13076|uniprotkb:Q13947|uniprotkb:Q6AZX1|uniprotkb:Q9UNL1|uniprotkb:B7Z8C4|ensembl:ENSP00000376500.3|ensembl:ENSP00000454207.1|ensembl:ENSP00000514678.1	psi-mi:q8d0l3_yerpe(display_long)|uniprotkb:gst(gene name)|psi-mi:gst(display_short)|uniprotkb:gst2(gene name synonym)|uniprotkb:YP_2153(locus name)|uniprotkb:y1968(locus name)	psi-mi:traf3_human(display_long)|uniprotkb:TRAF3(gene name)|psi-mi:TRAF3(display_short)|uniprotkb:CRAF1(gene name synonym)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:CD40-binding protein(gene name synonym)|uniprotkb:LMP1-associated protein 1(gene name synonym)|uniprotkb:CAP-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851695|imex:IM-13779-5594	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	rcsb pdb:4G9H|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|rcsb pdb:4GCI|interpro:IPR040079|interpro:IPR036249|interpro:IPR036282	"ensembl:ENSG00000131323.17(gene)|ensembl:ENST00000392745.8(transcript)|ensembl:ENST00000560371.5(transcript)|ensembl:ENST00000699894.1(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0001817""(regulation of cytokine production)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005739""(mitochondrion)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0007165""(signal transduction)|go:""GO:0008063""(Toll signaling pathway)|go:""GO:0008270""(zinc ion binding)|go:""GO:0009898""(cytoplasmic side of plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0019901""(protein kinase binding)|go:""GO:0019903""(protein phosphatase binding)|go:""GO:0030162""(regulation of proteolysis)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031996""(thioesterase binding)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032481""(positive regulation of type I interferon production)|go:""GO:0032648""(regulation of interferon-beta production)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035591""(signaling adaptor activity)|go:""GO:0035631""(CD40 receptor complex)|go:""GO:0035666""(TRIF-dependent toll-like receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0042981""(regulation of apoptotic process)|go:""GO:0043122""(regulation of canonical NF-kappaB signal transduction)|go:""GO:0050688""(regulation of defense response to virus)|go:""GO:0051607""(defense response to virus)|go:""GO:0060337""(type I interferon-mediated signaling pathway)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:1902554""(serine/threonine protein kinase complex)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR049342|interpro:IPR049440|mint:Q13114|rcsb pdb:1FLK|rcsb pdb:1FLL|rcsb pdb:1KZZ|rcsb pdb:1L0A|rcsb pdb:1RF3|rcsb pdb:1ZMS|rcsb pdb:2ECY|rcsb pdb:2GKW|rcsb pdb:8T5P|reactome:R-HSA-5602571|reactome:R-HSA-5668541|reactome:R-HSA-5676594|reactome:R-HSA-5689896|reactome:R-HSA-9013973|reactome:R-HSA-918233|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-9692916|reactome:R-HSA-9705671|reactome:R-HSA-9824878|reactome:R-HSA-9828211|refseq:NP_001186356.1|refseq:NP_003291.2|refseq:NP_663777.1|refseq:NP_663778.1|refseq:XP_011535420.1|refseq:XP_016877106.1|refseq:XP_016877107.1|dip:DIP-6222N|efo:""Orphanet:1930""|panther:PTHR10131(orthology-group)|ensembl:ENSP00000376500.3|ensembl:ENST00000539721.5|ensembl:ENSP00000445998.1|ensembl:ENSP00000454207.1|ensembl:ENSP00000514678.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:ZpxqSPqhSp4MKFNYg59eLwvcq8o632	rogid:9Tjx/USypDBBrPVyFOsLzM/bwzA9606	intact-crc:95F1E115762BF83F|rigid:dGOput2iY4XH5gl0Yu0HuIpMrCs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9Y2W1	uniprotkb:Q7CHI5	intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634.5|ensembl:ENSP00000433825.1	intact:EBI-2851724|uniprotkb:Q74VS0	psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym)	psi-mi:q7chi5_yerpe(display_long)|uniprotkb:cydD(gene name)|psi-mi:cydD(display_short)|uniprotkb:YPO1373(locus name)|uniprotkb:htrD(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851721|imex:IM-13779-5590	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_005110.2|refseq:NP_001308400.1|refseq:NP_001308402.1|ensembl:ENSG00000054118.15(gene)|ensembl:ENST00000354618.10(transcript)|ensembl:ENST00000469141.6(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016592""(mediator complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0042753""(positive regulation of circadian rhythm)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|panther:PTHR15268(orthology-group)"	"interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR014216(""ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD"")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|go:""GO:0005524""(ATP binding)|go:""GO:0005886""(plasma membrane)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0034040""(ATPase-coupled lipid transmembrane transporter activity)|go:""GO:0042883""(cysteine transport)|go:""GO:0055085""(transmembrane transport)|go:""GO:0140359""(ABC-type transporter activity)|interpro:IPR039421|interpro:IPR036640|refseq:YP_002346396.1|panther:PTHR24221(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606	rogid:Jwu8J1f58QDHESFwl/Z4+hrtNEM632	intact-crc:A295D2C259B4BC46|rigid:aLEHMtbn//RnhjafPYIStI//YAs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40127	uniprotkb:Q9Y2W1	intact:EBI-2844091|uniprotkb:Q0WAG2	intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634.5|ensembl:ENSP00000433825.1	psi-mi:cyaa_yerpe(display_long)|uniprotkb:cya(gene name)|psi-mi:cya(display_short)|uniprotkb:cyaA(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:YPO3848(locus name)|uniprotkb:y0382(locus name)|uniprotkb:YP_3199(locus name)	psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851733|imex:IM-13779-5591	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000274(Adenylate cyclase, class-I)|interpro:IPR024686|interpro:IPR024685|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006171""(cAMP biosynthetic process)|refseq:WP_002211468.1|refseq:YP_002348726.1|panther:PTHR38760(orthology-group)"	"refseq:NP_005110.2|refseq:NP_001308400.1|refseq:NP_001308402.1|ensembl:ENSG00000054118.15(gene)|ensembl:ENST00000354618.10(transcript)|ensembl:ENST00000469141.6(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016592""(mediator complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0042753""(positive regulation of circadian rhythm)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|panther:PTHR15268(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:l0RzY0/qkJ4UmTdMusK/+DQB0ow632	rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606	intact-crc:D7AD9AB6176CA03E|rigid:jDVoQeRYJAB1X87PX72ifRjY2yA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BMJ4	uniprotkb:Q13595	intact:EBI-2842684|uniprotkb:Q74SI5|uniprotkb:Q7CJF7|uniprotkb:A0A0H2W631	intact:EBI-2685506|ensembl:ENSP00000297071.4|uniprotkb:B4DUA9|uniprotkb:B4DQI6|uniprotkb:E9PD75	psi-mi:a0a3n4bmj4_yerpe(display_long)|uniprotkb:ptsI(gene name)|psi-mi:ptsI(display_short)|uniprotkb:Phosphotransferase system, enzyme I(gene name synonym)|uniprotkb:YPO2994(locus name)	psi-mi:tra2a_human(display_long)|uniprotkb:Transformer-2 protein homolog A(gene name synonym)|uniprotkb:TRA2A(gene name)|psi-mi:TRA2A(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851707|imex:IM-13779-5593	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR006318(Phosphoenolpyruvate-protein phosphotransferase)|interpro:IPR024692|interpro:IPR008731(Phosphotransferase system, PEP-utilising enzyme, N-terminal)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018274|interpro:IPR023151|go:""GO:0005737""(cytoplasm)|go:""GO:0008965""(phosphoenolpyruvate-protein phosphotransferase activity)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR040442|interpro:IPR036618|interpro:IPR036637|refseq:WP_002208490.1|refseq:YP_002347918.1|interpro:IPR050499|panther:PTHR46244(orthology-group)"	"refseq:NP_001269686.1|refseq:NP_001269687.1|refseq:NP_037425.1|ensembl:ENSG00000164548.12(gene)|ensembl:ENST00000297071.9(transcript)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0003723""(RNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005730""(nucleolus)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR050441|mint:Q13595|refseq:NP_001269688.1|refseq:XP_005249782.1|refseq:XP_016867578.1|refseq:XP_016867579.1|panther:PTHR48034(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:eLEHiZA3xPpbFGD5zpfuPDACip4632	rogid:JvcdzipB7mCy8eV3z8TaVjucLLM9606	intact-crc:64FA07FAAA81615D|rigid:5CDW+8TNYSIqm5A+VgfG6xdxh80	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YIB0	uniprotkb:Q9Y2W1	intact:EBI-2849936|uniprotkb:Q74W18|uniprotkb:Q0WDQ9|uniprotkb:Q7CJU5|uniprotkb:A0A384K8S0	intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634.5|ensembl:ENSP00000433825.1	psi-mi:a0a5p8yib0_yerpe(display_long)|uniprotkb:asnB(gene name)|psi-mi:asnB(display_short)|uniprotkb:YPO2623(locus name)	psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851714|imex:IM-13779-5592	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR001962(Asparagine synthase)|interpro:IPR017932|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033738|interpro:IPR029055|refseq:WP_002210348.1|go:""GO:0004066""(""asparagine synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006529""(asparagine biosynthetic process)|refseq:YP_002347579.1|interpro:IPR050795|panther:PTHR11772(orthology-group)"	"refseq:NP_005110.2|refseq:NP_001308400.1|refseq:NP_001308402.1|ensembl:ENSG00000054118.15(gene)|ensembl:ENST00000354618.10(transcript)|ensembl:ENST00000469141.6(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0000956""(nuclear-transcribed mRNA catabolic process)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0003677""(DNA binding)|go:""GO:0003712""(transcription coregulator activity)|go:""GO:0003713""(transcription coactivator activity)|go:""GO:0003723""(RNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006397""(mRNA processing)|go:""GO:0007623""(circadian rhythm)|go:""GO:0008380""(RNA splicing)|go:""GO:0016592""(mediator complex)|go:""GO:0016607""(nuclear speck)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0042753""(positive regulation of circadian rhythm)|go:""GO:0042809""(nuclear vitamin D receptor binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046966""(nuclear thyroid hormone receptor binding)|go:""GO:0048026""(positive regulation of mRNA splicing, via spliceosome)|go:""GO:0048255""(mRNA stabilization)|go:""GO:0051219""(phosphoprotein binding)|go:""GO:0070062""(extracellular exosome)|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|panther:PTHR15268(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/3AdfRR3qomx0JU+SwWtTPa2aeU632	rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606	intact-crc:69A156D5D0E7C197|rigid:G+9GPQP5I6AOgYGixcSZYW3a4oY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VBG2	uniprotkb:Q9Y296	intact:EBI-2849663	intact:EBI-722888|uniprotkb:B4DME1|uniprotkb:A8K3A5|ensembl:ENSP00000436005.1|ensembl:ENSP00000487467.1|intact:EBI-28967645	psi-mi:a0a6b3vbg2_yerpe(display_long)|uniprotkb:yapB(gene name)|psi-mi:yapB(display_short)|uniprotkb:y1345(locus name)	psi-mi:tppc4_human(display_long)|uniprotkb:Synbindin(gene name synonym)|uniprotkb:TRS23 homolog(gene name synonym)|uniprotkb:Hematopoietic stem/progenitor cell protein 172(gene name synonym)|uniprotkb:TRAPPC4(gene name)|psi-mi:TRAPPC4(display_short)|uniprotkb:SBDN(gene name synonym)|uniprotkb:CGI-104(orf name)|uniprotkb:HSPC172(orf name)|uniprotkb:PTD009(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851752|imex:IM-13779-5596	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004899(Pertactin)|interpro:IPR005546(Autotransporter beta-domain)|interpro:IPR006315(Outer membrane autotransporter barrel)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012332(Phage P22 tailspike)|interpro:IPR036709|uniprotkb:A0A6B3T6Y5(uniprot-removed-ac)|go:""GO:0019867""(outer membrane)|interpro:IPR051551"	"efo:""Orphanet:528084""|ensembl:ENSG00000196655.12(gene)|ensembl:ENSG00000280495.5(gene)|ensembl:ENST00000533632.6(transcript)|ensembl:ENST00000629243.3(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005737""(cytoplasm)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005795""(Golgi stack)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006901""(vesicle coating)|go:""GO:0006914""(autophagy)|go:""GO:0008021""(synaptic vesicle)|go:""GO:0016358""(dendrite development)|go:""GO:0030008""(TRAPP complex)|go:""GO:0030425""(dendrite)|go:""GO:0045202""(synapse)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0048786""(presynaptic active zone)|go:""GO:0098839""(postsynaptic density membrane)|go:""GO:0099022""(vesicle tethering)|go:""GO:1990071""(TRAPPII protein complex)|go:""GO:1990072""(TRAPPIII protein complex)|interpro:IPR007233(Sybindin-like protein)|interpro:IPR011012(Longin-like)|rcsb pdb:2J3T|rcsb pdb:2JSN|rcsb pdb:2ZMV|reactome:R-HSA-204005|reactome:R-HSA-3000170|reactome:R-HSA-8876198|refseq:NP_001305415.1|refseq:NP_001305417.1|refseq:NP_001305418.1|refseq:NP_001305419.1|refseq:NP_001305421.1|refseq:NP_001305423.1|refseq:NP_057230.1|dip:DIP-37871N|panther:PTHR23249(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:jNPx4rqCv9bEZelj7jbp42kW+NY632	rogid:9Dqiz8Vo+JYaAoNESIFFuhf2yc09606	intact-crc:DABFC9DDBA1A0FB4|rigid:cGivOTJcmW8cf+DyQoKvl4E+qUQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14773	uniprotkb:Q0WAP0	intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427.6	intact:EBI-2839765|uniprotkb:Q74R13|uniprotkb:Q8D1H9	psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)	psi-mi:ubid_yerpe(display_long)|uniprotkb:ubiD(gene name)|psi-mi:ubiD(display_short)|uniprotkb:Polyprenyl p-hydroxybenzoate decarboxylase(gene name synonym)|uniprotkb:YPO3769(locus name)|uniprotkb:y0461(locus name)|uniprotkb:YP_3279(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851759|imex:IM-13779-5599	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:284324""|efo:""Orphanet:228349""|ensembl:ENSG00000166340.18(gene)|ensembl:ENST00000299427.12(transcript)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006508""(proteolysis)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007040""(lysosome organization)|go:""GO:0007399""(nervous system development)|go:""GO:0007417""(central nervous system development)|go:""GO:0008233""(peptidase activity)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008240""(tripeptidyl-peptidase activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0035727""(lysophosphatidic acid binding)|go:""GO:0042277""(peptide binding)|go:""GO:0042470""(melanosome)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0045453""(bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070198""(protein localization to chromosome, telomeric region)|go:""GO:0120146""(sulfatide binding)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|interpro:IPR050819|mint:O14773|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|refseq:NP_000382.3|dip:DIP-47434N|panther:PTHR14218(orthology-group)"	"interpro:IPR002830(Carboxylyase-related)|interpro:IPR023677|refseq:YP_002348648.1|interpro:IPR048304|interpro:IPR049381|interpro:IPR049383|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0008694""(3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002215917.1|panther:PTHR30108(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606	rogid:6T5bdpfVWr02Z+TIui0xRWwmcUs632	intact-crc:C109EE0462F4366A|rigid:gObSqAfhoY4QUEhIkc1EFU9sT14	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14773	uniprotkb:A0A380SB10	intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427.6	intact:EBI-2851776|uniprotkb:Q74TL9|uniprotkb:A0A3N4B0C2|uniprotkb:Q7CIQ5|uniprotkb:Q0WEH3	psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)	psi-mi:a0a380sb10_yerpe(display_long)|uniprotkb:YPO2348(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851773|imex:IM-13779-5597	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:284324""|efo:""Orphanet:228349""|ensembl:ENSG00000166340.18(gene)|ensembl:ENST00000299427.12(transcript)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006508""(proteolysis)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007040""(lysosome organization)|go:""GO:0007399""(nervous system development)|go:""GO:0007417""(central nervous system development)|go:""GO:0008233""(peptidase activity)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008240""(tripeptidyl-peptidase activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0035727""(lysophosphatidic acid binding)|go:""GO:0042277""(peptide binding)|go:""GO:0042470""(melanosome)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0045453""(bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070198""(protein localization to chromosome, telomeric region)|go:""GO:0120146""(sulfatide binding)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|interpro:IPR050819|mint:O14773|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|refseq:NP_000382.3|dip:DIP-47434N|panther:PTHR14218(orthology-group)"	interpro:IPR007413(Protein of unknown function DUF463, YcjX-like protein)|refseq:WP_002210979.1|refseq:YP_002347315.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606	rogid:hgdtdL3QZVTZ0qSQOVxFJfRMMdA632	intact-crc:87AE728A7D280DAA|rigid:uGCqfmsIn45hyBHTJ2JBaZAxOhI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O14773	uniprotkb:A0A0H2W1Q2	intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427.6	intact:EBI-2841226|uniprotkb:Q0WBC6|uniprotkb:Q74X91|uniprotkb:Q7CKK4|uniprotkb:A0A380PGZ4	psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)	psi-mi:a0a0h2w1q2_yerpe(display_long)|uniprotkb:YPO3523(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851766|imex:IM-13779-5598	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:284324""|efo:""Orphanet:228349""|ensembl:ENSG00000166340.18(gene)|ensembl:ENST00000299427.12(transcript)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006508""(proteolysis)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007040""(lysosome organization)|go:""GO:0007399""(nervous system development)|go:""GO:0007417""(central nervous system development)|go:""GO:0008233""(peptidase activity)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008240""(tripeptidyl-peptidase activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0035727""(lysophosphatidic acid binding)|go:""GO:0042277""(peptide binding)|go:""GO:0042470""(melanosome)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0045453""(bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070198""(protein localization to chromosome, telomeric region)|go:""GO:0120146""(sulfatide binding)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|interpro:IPR050819|mint:O14773|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|refseq:NP_000382.3|dip:DIP-47434N|panther:PTHR14218(orthology-group)"	"refseq:YP_002348412.1|interpro:IPR007452(Protein of unknown function DUF490)|go:""GO:0005886""(plasma membrane)|go:""GO:0009306""(protein secretion)|refseq:WP_002210167.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606	rogid:EAskKEVuhdiV6Cq5qm8N8/ACmOw632	intact-crc:17BAE7A033CC72B4|rigid:Rbgp+4JI8/3/a8lHp+tNpBAST60	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O15533	uniprotkb:Q8ZFX5	intact:EBI-874801|uniprotkb:O15210|uniprotkb:O15272|uniprotkb:Q5STJ8|uniprotkb:Q5STK6|uniprotkb:Q5STQ5|uniprotkb:Q5STQ6|uniprotkb:Q66K65|uniprotkb:Q96KK7|uniprotkb:Q9HAN8|uniprotkb:Q9UEE0|uniprotkb:Q9UEE4|uniprotkb:Q9UIZ6|uniprotkb:Q9Y6K2|uniprotkb:B2ZUA4|uniprotkb:E9PGM2|uniprotkb:B0V0A6|uniprotkb:A2AB91|uniprotkb:A2ABC0|uniprotkb:B0V003|ensembl:ENSP00000363700.3|ensembl:ENSP00000372543.4|ensembl:ENSP00000372684.4|ensembl:ENSP00000372685.2|ensembl:ENSP00000378546.3|ensembl:ENSP00000395701.2|ensembl:ENSP00000402087.1|ensembl:ENSP00000407195.2	intact:EBI-2851740|uniprotkb:Q0WGM4	psi-mi:tpsn_human(display_long)|uniprotkb:TAP-binding protein(gene name synonym)|uniprotkb:TAP-associated protein(gene name synonym)|uniprotkb:NGS-17(gene name synonym)|uniprotkb:TAPBP(gene name)|psi-mi:TAPBP(display_short)|uniprotkb:NGS17(gene name synonym)|uniprotkb:TAPA(gene name synonym)	psi-mi:hisx_yerpe(display_long)|uniprotkb:hisD(gene name)|psi-mi:hisD(display_short)|uniprotkb:YPO1548(locus name)|uniprotkb:y2621(locus name)|uniprotkb:YP_1437(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851745|imex:IM-13779-5595	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"panther:PTHR23411(orthology-group)|ensembl:ENSG00000112493.12(gene)|ensembl:ENSG00000206208.11(gene)|ensembl:ENSG00000206281.11(gene)|ensembl:ENSG00000231925.14(gene)|ensembl:ENSG00000236490.9(gene)|ensembl:ENST00000374572.7(transcript)|ensembl:ENST00000383066.8(transcript)|ensembl:ENST00000383197.8(transcript)|ensembl:ENST00000383198.6(transcript)|ensembl:ENST00000395114.7(transcript)|ensembl:ENST00000417059.5(transcript)|ensembl:ENST00000434618.7(transcript)|ensembl:ENST00000456807.6(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0002398""(MHC class Ib protein complex assembly)|go:""GO:0002502""(peptide antigen assembly with MHC class I protein complex)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006890""(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0019885""(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:""GO:0023024""(MHC class I protein complex binding)|go:""GO:0030670""(phagocytic vesicle membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0042288""(MHC class I protein binding)|go:""GO:0042605""(peptide antigen binding)|go:""GO:0042824""(MHC class I peptide loading complex)|go:""GO:0044183""(protein folding chaperone)|go:""GO:0046978""(TAP1 binding)|go:""GO:0046979""(TAP2 binding)|go:""GO:0050823""(peptide antigen stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0060090""(molecular adaptor activity)|go:""GO:0061635""(regulation of protein complex stability)|go:""GO:0061779""(Tapasin-ERp57 complex)|go:""GO:0062061""(TAP complex binding)|go:""GO:0065003""(protein-containing complex assembly)|go:""GO:0098553""(lumenal side of endoplasmic reticulum membrane)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008056(Tapasin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR050380|mint:O15533|rcsb pdb:3F8U|rcsb pdb:6ENY|rcsb pdb:7QNG|rcsb pdb:7QPD|rcsb pdb:7TUE|rcsb pdb:7TUF|rcsb pdb:7TUG|reactome:R-HSA-1236974|reactome:R-HSA-983170|refseq:NP_003181.3|refseq:NP_757345.2|refseq:NP_757346.2|efo:""Orphanet:34592"""	"interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR001692(Histidinol dehydrogenase)|interpro:IPR022695|interpro:IPR012131(Histidinol dehydrogenase, prokaryotic)|refseq:WP_002211895.1|go:""GO:0000105""(L-histidine biosynthetic process)|go:""GO:0004399""(histidinol dehydrogenase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0008270""(zinc ion binding)|go:""GO:0051287""(NAD binding)|refseq:YP_002346564.1|panther:PTHR21256(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:u8fYbbxoezTNCan0J7q9PY+GYLs9606	rogid:aXT+/ioqFLvYG1ayljhfqLE1ikU632	intact-crc:0B9BE5E3ED03BC84|rigid:DRLgmPOmu7dvtRXXRwL0B+BTK8M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P40127	uniprotkb:O14773	intact:EBI-2844091|uniprotkb:Q0WAG2	intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427.6	psi-mi:cyaa_yerpe(display_long)|uniprotkb:cya(gene name)|psi-mi:cya(display_short)|uniprotkb:cyaA(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:YPO3848(locus name)|uniprotkb:y0382(locus name)|uniprotkb:YP_3199(locus name)	psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851798|imex:IM-13779-5604	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000274(Adenylate cyclase, class-I)|interpro:IPR024686|interpro:IPR024685|go:""GO:0004016""(adenylate cyclase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006171""(cAMP biosynthetic process)|refseq:WP_002211468.1|refseq:YP_002348726.1|panther:PTHR38760(orthology-group)"	"efo:""Orphanet:284324""|efo:""Orphanet:228349""|ensembl:ENSG00000166340.18(gene)|ensembl:ENST00000299427.12(transcript)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006508""(proteolysis)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007040""(lysosome organization)|go:""GO:0007399""(nervous system development)|go:""GO:0007417""(central nervous system development)|go:""GO:0008233""(peptidase activity)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008240""(tripeptidyl-peptidase activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0035727""(lysophosphatidic acid binding)|go:""GO:0042277""(peptide binding)|go:""GO:0042470""(melanosome)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0045453""(bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070198""(protein localization to chromosome, telomeric region)|go:""GO:0120146""(sulfatide binding)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|interpro:IPR050819|mint:O14773|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|refseq:NP_000382.3|dip:DIP-47434N|panther:PTHR14218(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:l0RzY0/qkJ4UmTdMusK/+DQB0ow632	rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606	intact-crc:89D6CFB67A045EC2|rigid:gZDuxPx6UUkQiMkYnG2nrn8qLns	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YCT6	uniprotkb:O14773	intact:EBI-2845671|uniprotkb:Q74QB9|uniprotkb:Q0WIG8|uniprotkb:Q7CGU7|uniprotkb:A0A384L4P0	intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427.6	psi-mi:a0a5p8yct6_yerpe(display_long)|uniprotkb:YPO0870(locus name)	psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851791|imex:IM-13779-5601	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:YP_002345920.1	"efo:""Orphanet:284324""|efo:""Orphanet:228349""|ensembl:ENSG00000166340.18(gene)|ensembl:ENST00000299427.12(transcript)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006508""(proteolysis)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007040""(lysosome organization)|go:""GO:0007399""(nervous system development)|go:""GO:0007417""(central nervous system development)|go:""GO:0008233""(peptidase activity)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008240""(tripeptidyl-peptidase activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0035727""(lysophosphatidic acid binding)|go:""GO:0042277""(peptide binding)|go:""GO:0042470""(melanosome)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0045453""(bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070198""(protein localization to chromosome, telomeric region)|go:""GO:0120146""(sulfatide binding)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|interpro:IPR050819|mint:O14773|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|refseq:NP_000382.3|dip:DIP-47434N|panther:PTHR14218(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:AOWwmv4Vb6xHJQUvmRTiMlJYQCA632	rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606	intact-crc:B3C6070E2D8330C1|rigid:uBUupFb1kBxn6V6l2KNdFf6ShJw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W3V7	uniprotkb:O14773	intact:EBI-2839946|uniprotkb:A0A384LA47|uniprotkb:Q74UY8|uniprotkb:Q0WFV3|uniprotkb:Q7CHZ9|uniprotkb:A0A5P8YEB4	intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427.6	psi-mi:a0a0h2w3v7_yerpe(display_long)|uniprotkb:flaV(gene name)|psi-mi:flaV(display_short)|uniprotkb:Flagellar cap protein(gene name synonym)|uniprotkb:flbC(gene name synonym)|uniprotkb:fliD(gene name synonym)|uniprotkb:YPO1841(locus name)	psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851784|imex:IM-13779-5600	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002346835.1|interpro:IPR010809(Flagellar hook-associated 2, C-terminal)|interpro:IPR003481(Flagellar hook-associated protein 2, N-terminal)|go:""GO:0005576""(extracellular region)|go:""GO:0007155""(cell adhesion)|go:""GO:0009421""(bacterial-type flagellum filament cap)|go:""GO:0009424""(bacterial-type flagellum hook)|refseq:WP_002211150.1|interpro:IPR040026"	"efo:""Orphanet:284324""|efo:""Orphanet:228349""|ensembl:ENSG00000166340.18(gene)|ensembl:ENST00000299427.12(transcript)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006508""(proteolysis)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007040""(lysosome organization)|go:""GO:0007399""(nervous system development)|go:""GO:0007417""(central nervous system development)|go:""GO:0008233""(peptidase activity)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008240""(tripeptidyl-peptidase activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0035727""(lysophosphatidic acid binding)|go:""GO:0042277""(peptide binding)|go:""GO:0042470""(melanosome)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0045453""(bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070198""(protein localization to chromosome, telomeric region)|go:""GO:0120146""(sulfatide binding)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|interpro:IPR050819|mint:O14773|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|refseq:NP_000382.3|dip:DIP-47434N|panther:PTHR14218(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:y6JIeGlhmIELicCmvORRUOwywBM632	rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606	intact-crc:48865FB09C13036D|rigid:rJVCxsUibeBNfVEbheFXDkVSj88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZA85	uniprotkb:O14773	intact:EBI-2851805|uniprotkb:Q0WA87	intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427.6	psi-mi:arge_yerpe(display_long)|uniprotkb:argE(gene name)|psi-mi:argE(display_short)|uniprotkb:N-acetylornithinase(gene name synonym)|uniprotkb:YPO3928(locus name)|uniprotkb:y0309(locus name)|uniprotkb:YP_3122(locus name)	psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851810|imex:IM-13779-5603	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010169(""Acetylornithine deacetylase (ArgE)"")|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008777""(acetylornithine deacetylase activity)|interpro:IPR036264|refseq:YP_002348801.1|interpro:IPR050072|panther:PTHR43808(orthology-group)"	"efo:""Orphanet:284324""|efo:""Orphanet:228349""|ensembl:ENSG00000166340.18(gene)|ensembl:ENST00000299427.12(transcript)|go:""GO:0004175""(endopeptidase activity)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0005764""(lysosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006508""(proteolysis)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0007040""(lysosome organization)|go:""GO:0007399""(nervous system development)|go:""GO:0007417""(central nervous system development)|go:""GO:0008233""(peptidase activity)|go:""GO:0008236""(serine-type peptidase activity)|go:""GO:0008240""(tripeptidyl-peptidase activity)|go:""GO:0030163""(protein catabolic process)|go:""GO:0030855""(epithelial cell differentiation)|go:""GO:0035727""(lysophosphatidic acid binding)|go:""GO:0042277""(peptide binding)|go:""GO:0042470""(melanosome)|go:""GO:0043171""(peptide catabolic process)|go:""GO:0043202""(lysosomal lumen)|go:""GO:0045121""(membrane raft)|go:""GO:0045453""(bone resorption)|go:""GO:0046872""(metal ion binding)|go:""GO:0050885""(neuromuscular process controlling balance)|go:""GO:0055037""(recycling endosome)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070198""(protein localization to chromosome, telomeric region)|go:""GO:0120146""(sulfatide binding)|go:""GO:1905146""(lysosomal protein catabolic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|interpro:IPR050819|mint:O14773|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|refseq:NP_000382.3|dip:DIP-47434N|panther:PTHR14218(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/28	rogid:MOUN4te1AE/Lneulxil2MqJd1p8632	rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606	intact-crc:49322BD2EBCEECD0|rigid:3ntOhEAOIZbu2P2+zDr62XWj56o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O43399	uniprotkb:Q8D1P4	intact:EBI-782604|uniprotkb:Q5U0E0|uniprotkb:Q5JWU6|uniprotkb:Q9H3Z6|intact:EBI-1043547|uniprotkb:O43398|uniprotkb:Q5JWU5|uniprotkb:Q5JWU8|uniprotkb:E1P5G7|uniprotkb:B4DPJ6|ensembl:ENSP00000343547.4	intact:EBI-2845144	psi-mi:tpd54_human(display_long)|uniprotkb:Tumor protein D52-like 2(gene name synonym)|uniprotkb:TPD52L2(gene name)|psi-mi:TPD52L2(display_short)	psi-mi:q8d1p4_yerpe(display_long)|uniprotkb:y0195(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851817|imex:IM-13779-5602	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001230821.1|refseq:NP_003279.2|refseq:NP_955393.1|refseq:NP_955395.1|refseq:NP_955394.1|refseq:NP_955392.1|ensembl:ENSG00000101150.18(gene)|ensembl:ENST00000346249.9(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005975""(carbohydrate metabolic process)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|interpro:IPR012341(Six-hairpin glycosidase)|mint:O43399|panther:PTHR19307(orthology-group)"	interpro:IPR032712|interpro:IPR025263|interpro:IPR011836(Conserved hypothetical protein CHP02099)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:asqRlZnmqIzXCJ5TAHjxKcj046g9606	rogid:k1ALZgWrTdqeyJ1mZBZgusKWD8Y632	intact-crc:147E8B1E414FF46A|rigid:a+hBrB600wawg6tACQbUGIm3J6o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75365	uniprotkb:A0A2S9PLF9	intact:EBI-1043866|uniprotkb:Q8IVN5|uniprotkb:Q99849|uniprotkb:Q9BTW5|ensembl:ENSP00000331730.2|ensembl:ENSP00000332274.1|ensembl:ENSP00000428976.1|ensembl:ENSP00000484500.1|ensembl:ENSP00000487595.1|ensembl:ENSP00000505068.1|ensembl:ENSP00000516927.1|ensembl:ENSP00000516928.1|ensembl:ENSP00000516929.1|ensembl:ENSP00000516930.1	intact:EBI-2841354|uniprotkb:Q74X44|uniprotkb:Q0WBI4|uniprotkb:Q7CKG9|uniprotkb:A0A380PH15	psi-mi:tp4a3_human(display_long)|uniprotkb:PTP4A3(gene name)|psi-mi:PTP4A3(display_short)|uniprotkb:PRL3(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 4a3(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase of regenerating liver 3(gene name synonym)|uniprotkb:PRL-R(gene name synonym)	psi-mi:a0a2s9plf9_yerpe(display_long)|uniprotkb:phnP(gene name)|psi-mi:phnP(display_short)|uniprotkb:YPO3465(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851841|imex:IM-13779-5609	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009010.2|refseq:NP_116000.1|refseq:XP_005250821.1|refseq:XP_011515105.1|refseq:XP_011515107.1|refseq:XP_016868487.1|ensembl:ENSG00000184489.13(gene)|ensembl:ENSG00000275575.4(gene)|ensembl:ENSG00000291470.1(gene)|ensembl:ENST00000329397.6(transcript)|ensembl:ENST00000349124.3(transcript)|ensembl:ENST00000521578.6(transcript)|ensembl:ENST00000622569.3(transcript)|ensembl:ENST00000633518.1(transcript)|ensembl:ENST00000680615.1(transcript)|ensembl:ENST00000707616.1(transcript)|ensembl:ENST00000707617.1(transcript)|ensembl:ENST00000707618.1(transcript)|ensembl:ENST00000707619.1(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0043117""(positive regulation of vascular permeability)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1900746""(regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904951""(positive regulation of establishment of protein localization)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR020422|interpro:IPR029021|interpro:IPR050561|mint:O75365|rcsb pdb:1R6H|rcsb pdb:1V3A|rcsb pdb:2MBC|rcsb pdb:5TSR|panther:PTHR23339(orthology-group)"	"interpro:IPR001279(Beta-lactamase-like)|interpro:IPR017693(Phosphonate metabolism protein PhnP)|go:""GO:0008081""(phosphoric diester hydrolase activity)|go:""GO:0019700""(organic phosphonate catabolic process)|refseq:WP_002209284.1|refseq:YP_002348354.1|interpro:IPR035682|interpro:IPR036866|interpro:IPR050419"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:anMW5wCN5ZmFMYMN0ExOLqBoeEU9606	rogid:inlYtqvN2O/ToeHxbyY8+4PwJr0632	intact-crc:F73C5A3003E59309|rigid:vSAvnfyQxmW588N8KNwpfS4ej/o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O94842	uniprotkb:Q8CK83	intact:EBI-948613|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0|ensembl:ENSP00000393080.3|ensembl:ENSP00000477868.1	intact:EBI-2851851|uniprotkb:Q74QS6	psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym)	psi-mi:q8ck83_yerpe(display_long)|uniprotkb:accC1(gene name)|psi-mi:accC1(display_short)|uniprotkb:YP_3384(locus name)|uniprotkb:y4042(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851848|imex:IM-13779-5608	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055643.1|refseq:NP_001290452.1|ensembl:ENSG00000092203.15(gene)|ensembl:ENST00000448790.7(transcript)|ensembl:ENST00000613569.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR051365|mint:O94842|panther:PTHR45781(orthology-group)"	"interpro:IPR011761(ATP-grasp fold)|go:""GO:0005524""(ATP binding)|go:""GO:0016874""(ligase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR052032"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606	rogid:zWNetqBcgNgoffpGm1WuBpGKZiA632	intact-crc:7422B0BD3F256E3F|rigid:fszhB7+C0XfK75iscvqXAdTr6gg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O75365	uniprotkb:Q8CKI1	intact:EBI-1043866|uniprotkb:Q8IVN5|uniprotkb:Q99849|uniprotkb:Q9BTW5|ensembl:ENSP00000331730.2|ensembl:ENSP00000332274.1|ensembl:ENSP00000428976.1|ensembl:ENSP00000484500.1|ensembl:ENSP00000487595.1|ensembl:ENSP00000505068.1|ensembl:ENSP00000516927.1|ensembl:ENSP00000516928.1|ensembl:ENSP00000516929.1|ensembl:ENSP00000516930.1	intact:EBI-2851831	psi-mi:tp4a3_human(display_long)|uniprotkb:PTP4A3(gene name)|psi-mi:PTP4A3(display_short)|uniprotkb:PRL3(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 4a3(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase of regenerating liver 3(gene name synonym)|uniprotkb:PRL-R(gene name synonym)	psi-mi:q8cki1_yerpe(display_long)|uniprotkb:y3454(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851834|imex:IM-13779-5606	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_009010.2|refseq:NP_116000.1|refseq:XP_005250821.1|refseq:XP_011515105.1|refseq:XP_011515107.1|refseq:XP_016868487.1|ensembl:ENSG00000184489.13(gene)|ensembl:ENSG00000275575.4(gene)|ensembl:ENSG00000291470.1(gene)|ensembl:ENST00000329397.6(transcript)|ensembl:ENST00000349124.3(transcript)|ensembl:ENST00000521578.6(transcript)|ensembl:ENST00000622569.3(transcript)|ensembl:ENST00000633518.1(transcript)|ensembl:ENST00000680615.1(transcript)|ensembl:ENST00000707616.1(transcript)|ensembl:ENST00000707617.1(transcript)|ensembl:ENST00000707618.1(transcript)|ensembl:ENST00000707619.1(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0043117""(positive regulation of vascular permeability)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1900746""(regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904951""(positive regulation of establishment of protein localization)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR020422|interpro:IPR029021|interpro:IPR050561|mint:O75365|rcsb pdb:1R6H|rcsb pdb:1V3A|rcsb pdb:2MBC|rcsb pdb:5TSR|panther:PTHR23339(orthology-group)"	-	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:anMW5wCN5ZmFMYMN0ExOLqBoeEU9606	rogid:iNI68Dsb+Pq0fztjZLD9gZMsojA632	intact-crc:B425F05BC5ADE177|rigid:VYOJZJ0s78NRCh8iNf3H+17rAVI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YGL4	uniprotkb:O75365	intact:EBI-2842269	intact:EBI-1043866|uniprotkb:Q8IVN5|uniprotkb:Q99849|uniprotkb:Q9BTW5|ensembl:ENSP00000331730.2|ensembl:ENSP00000332274.1|ensembl:ENSP00000428976.1|ensembl:ENSP00000484500.1|ensembl:ENSP00000487595.1|ensembl:ENSP00000505068.1|ensembl:ENSP00000516927.1|ensembl:ENSP00000516928.1|ensembl:ENSP00000516929.1|ensembl:ENSP00000516930.1	psi-mi:a0a5p8ygl4_yerpe(display_long)|uniprotkb:y2085(locus name)|uniprotkb:rnfC(gene name)|psi-mi:rnfC(display_short)|uniprotkb:Rnf electron transport complex subunit C(gene name synonym)	psi-mi:tp4a3_human(display_long)|uniprotkb:PTP4A3(gene name)|psi-mi:PTP4A3(display_short)|uniprotkb:PRL3(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 4a3(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase of regenerating liver 3(gene name synonym)|uniprotkb:PRL-R(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851824|imex:IM-13779-5605	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010208(Electron transport complex, RnfC)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR017896|interpro:IPR017900|interpro:IPR019554|interpro:IPR026902|interpro:IPR037225|refseq:WP_002223606.1|uniprotkb:Q8D0I9(uniprot-removed-ac)|go:""GO:0005886""(plasma membrane)|go:""GO:0009055""(electron transfer activity)|go:""GO:0022900""(electron transport chain)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)"	"refseq:NP_009010.2|refseq:NP_116000.1|refseq:XP_005250821.1|refseq:XP_011515105.1|refseq:XP_011515107.1|refseq:XP_016868487.1|ensembl:ENSG00000184489.13(gene)|ensembl:ENSG00000275575.4(gene)|ensembl:ENSG00000291470.1(gene)|ensembl:ENST00000329397.6(transcript)|ensembl:ENST00000349124.3(transcript)|ensembl:ENST00000521578.6(transcript)|ensembl:ENST00000622569.3(transcript)|ensembl:ENST00000633518.1(transcript)|ensembl:ENST00000680615.1(transcript)|ensembl:ENST00000707616.1(transcript)|ensembl:ENST00000707617.1(transcript)|ensembl:ENST00000707618.1(transcript)|ensembl:ENST00000707619.1(transcript)|go:""GO:0004725""(protein tyrosine phosphatase activity)|go:""GO:0004726""(non-membrane spanning protein tyrosine phosphatase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0030946""(protein tyrosine phosphatase activity, metal-dependent)|go:""GO:0043117""(positive regulation of vascular permeability)|go:""GO:0043542""(endothelial cell migration)|go:""GO:0140793""(histone H2AXY142 phosphatase activity)|go:""GO:1900746""(regulation of vascular endothelial growth factor signaling pathway)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1904951""(positive regulation of establishment of protein localization)|go:""GO:1990830""(cellular response to leukemia inhibitory factor)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR020422|interpro:IPR029021|interpro:IPR050561|mint:O75365|rcsb pdb:1R6H|rcsb pdb:1V3A|rcsb pdb:2MBC|rcsb pdb:5TSR|panther:PTHR23339(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:NRqQl9HrLq9sWIRyxpxhQ0JPxQo632	rogid:anMW5wCN5ZmFMYMN0ExOLqBoeEU9606	intact-crc:861EC750933E4308|rigid:hbzTafz/zVfLSdeB4hjIyZOnTu4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YLP6	uniprotkb:O94842	intact:EBI-2851863|uniprotkb:Q74PI1|uniprotkb:Q0WB32|uniprotkb:Q7CL42|uniprotkb:A0A384KC21	intact:EBI-948613|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0|ensembl:ENSP00000393080.3|ensembl:ENSP00000477868.1	psi-mi:a0a5p8ylp6_yerpe(display_long)|uniprotkb:rbsK(gene name)|psi-mi:rbsK(display_short)|uniprotkb:YPO3621(locus name)	psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851860|imex:IM-13779-5607	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002173(Carbohydrate/puine kinase, PfkB, conserved site)|interpro:IPR029056|interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR002139(Ribokinase)|interpro:IPR011877(Ribokinase, bacterial)|go:""GO:0004747""(ribokinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0019303""(D-ribose catabolic process)|go:""GO:0046872""(metal ion binding)|refseq:YP_002348506.1|panther:PTHR10584(orthology-group)"	"refseq:NP_055643.1|refseq:NP_001290452.1|ensembl:ENSG00000092203.15(gene)|ensembl:ENST00000448790.7(transcript)|ensembl:ENST00000613569.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR051365|mint:O94842|panther:PTHR45781(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:+UV0W+StaR2UinU91X3pSC0R/BU632	rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606	intact-crc:41B414DED62CE5CD|rigid:URAKDUfJS5cD+ueYJThNBUUDzHg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4BEU0	uniprotkb:O94842	intact:EBI-2845592|uniprotkb:Q74TN2|uniprotkb:A0A0H2W6F3|uniprotkb:Q7CIP7|uniprotkb:A0A384KST0	intact:EBI-948613|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0|ensembl:ENSP00000393080.3|ensembl:ENSP00000477868.1	psi-mi:a0a3n4beu0_yerpe(display_long)|uniprotkb:nifJ(gene name)|psi-mi:nifJ(display_short)|uniprotkb:YPO2334(locus name)	psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851872|imex:IM-13779-5610	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR033412|interpro:IPR017896|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895(""Pyruvate:ferredoxin (flavodoxin) oxidoreductase"")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR017900|interpro:IPR029061|refseq:WP_002210993.1|go:""GO:0005506""(iron ion binding)|go:""GO:0006979""(response to oxidative stress)|go:""GO:0016903""(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:""GO:0022900""(electron transport chain)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0044281""(small molecule metabolic process)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR037112|refseq:YP_002347301.1|interpro:IPR050722|panther:PTHR32154(orthology-group)"	"refseq:NP_055643.1|refseq:NP_001290452.1|ensembl:ENSG00000092203.15(gene)|ensembl:ENST00000448790.7(transcript)|ensembl:ENST00000613569.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR051365|mint:O94842|panther:PTHR45781(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:mWLfUpVvpqPQwqgnU4c6+JWJC/g632	rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606	intact-crc:D013A316D527DC94|rigid:DIE7ZaM6ls9CrlpbdJrGwYlXcfk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NS56	uniprotkb:Q8ZFU4	intact:EBI-1996473|uniprotkb:O43273|uniprotkb:Q6P987|uniprotkb:Q9NS55|uniprotkb:Q9UNR9|ensembl:ENSP00000353735.2	intact:EBI-2847230|uniprotkb:Q0WGJ0	psi-mi:toprs_human(display_long)|uniprotkb:TOPORS(gene name)|psi-mi:TOPORS(display_short)|uniprotkb:LUN(gene name synonym)|uniprotkb:TP53BPL(gene name synonym)|uniprotkb:SUMO1-protein E3 ligase Topors(gene name synonym)|uniprotkb:Topoisomerase I-binding RING finger protein(gene name synonym)|uniprotkb:Topoisomerase I-binding arginine/serine-rich protein(gene name synonym)|uniprotkb:Tumor suppressor p53-binding protein 3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Topors(gene name synonym)	psi-mi:pyrc_yerpe(display_long)|uniprotkb:pyrC(gene name)|psi-mi:pyrC(display_short)|uniprotkb:YPO1587(locus name)|uniprotkb:y1746(locus name)|uniprotkb:YP_2265(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851886|imex:IM-13779-5614	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000197579.8(gene)|ensembl:ENST00000360538.7(transcript)|go:""GO:0000151""(ubiquitin ligase complex)|go:""GO:0000209""(protein polyubiquitination)|go:""GO:0000922""(spindle pole)|go:""GO:0000930""(gamma-tubulin complex)|go:""GO:0003677""(DNA binding)|go:""GO:0003823""(antigen binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005814""(centriole)|go:""GO:0006351""(DNA-templated transcription)|go:""GO:0006511""(ubiquitin-dependent protein catabolic process)|go:""GO:0006513""(protein monoubiquitination)|go:""GO:0006974""(DNA damage response)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0010842""(retina layer formation)|go:""GO:0016605""(PML body)|go:""GO:0016607""(nuclear speck)|go:""GO:0016925""(protein sumoylation)|go:""GO:0019789""(SUMO transferase activity)|go:""GO:0030496""(midbody)|go:""GO:0032391""(photoreceptor connecting cilium)|go:""GO:0034504""(protein localization to nucleus)|go:""GO:0035845""(photoreceptor cell outer segment organization)|go:""GO:0036064""(ciliary basal body)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042771""(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043161""(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:""GO:0044547""(DNA topoisomerase binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0046548""(retinal rod cell development)|go:""GO:0046549""(retinal cone cell development)|go:""GO:0046872""(metal ion binding)|go:""GO:0051457""(maintenance of protein location in nucleus)|go:""GO:0061630""(ubiquitin protein ligase activity)|go:""GO:0070936""(protein K48-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|mint:Q9NS56|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4755510|refseq:NP_001182551.1|refseq:NP_005793.2|panther:PTHR46077(orthology-group)|efo:""Orphanet:2754""|efo:""Orphanet:791"""	"interpro:IPR006680(Amidohydrolase 1)|interpro:IPR004721(Dihydroorotase homodimeric type)|interpro:IPR002195(Dihydroorotase, conserved site)|rcsb pdb:6CTY|refseq:WP_002213109.1|go:""GO:0004151""(dihydroorotase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006221""(pyrimidine nucleotide biosynthetic process)|go:""GO:0008270""(zinc ion binding)|go:""GO:0044205""('de novo' UMP biosynthetic process)|interpro:IPR032466|refseq:YP_002346598.1|panther:PTHR43137(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8KlxsG2SOxo/Li/zMRdUsXbhNlg9606	rogid:jT3nxUan332vNjWdPuH2/URVCNM632	intact-crc:7D0EE7ECA91263C4|rigid:1fGqhMCzSjJoooT7fgHLViJVifQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NDV7	uniprotkb:P68587	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	intact:EBI-2844901|uniprotkb:P40295	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	psi-mi:yscp_yerpe(display_long)|uniprotkb:yscP(gene name)|psi-mi:yscP(display_short)|uniprotkb:YPCD1.42(locus name)|uniprotkb:y5036(locus name)|uniprotkb:y0039(locus name)|uniprotkb:YP_pCD41(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851893|imex:IM-13779-5613	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"interpro:IPR021136|interpro:IPR013354(Type III secretion system needle length determinant)|refseq:NP_395176.1|refseq:NP_857740.1|refseq:NP_857935.1|interpro:IPR038610|refseq:WP_002212950.1|go:""GO:0005737""(cytoplasm)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	rogid:zcO5sjasSYcu4J016bv9I08pEXo632	intact-crc:996AF7066DB2F79C|rigid:7VjIsdxDnvsUmxXkM4iL21SK+88	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380PC31	uniprotkb:O94842	intact:EBI-2847467|uniprotkb:Q74TQ8|uniprotkb:Q7CII9|uniprotkb:Q0WEL8	intact:EBI-948613|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0|ensembl:ENSP00000393080.3|ensembl:ENSP00000477868.1	psi-mi:a0a380pc31_yerpe(display_long)|uniprotkb:pntA(gene name)|psi-mi:pntA(display_short)|uniprotkb:YPO2303(locus name)	psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851879|imex:IM-13779-5611	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026255|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR024605|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|refseq:WP_002211019.1|go:""GO:0005886""(plasma membrane)|go:""GO:0006740""(NADPH regeneration)|go:""GO:0008750""(""proton-translocating NAD(P)+ transhydrogenase activity"")|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0050661""(NADP binding)|interpro:IPR036291|refseq:YP_002347270.1|panther:PTHR10160(orthology-group)"	"refseq:NP_055643.1|refseq:NP_001290452.1|ensembl:ENSG00000092203.15(gene)|ensembl:ENST00000448790.7(transcript)|ensembl:ENST00000613569.4(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0031490""(chromatin DNA binding)|go:""GO:0072357""(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR051365|mint:O94842|panther:PTHR45781(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FVP+mtiTI6lGXb+9R8nUXq43tEc632	rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606	intact-crc:2E87A6BE469844B2|rigid:YKeC1m6ssDLqGwILkxWKkjDh55k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NDV7	uniprotkb:Q8ZD91	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	intact:EBI-2851903|uniprotkb:Q0WDJ3	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	psi-mi:gch1l_yerpe(display_long)|uniprotkb:YPO2697(locus name)|uniprotkb:YP_2501(locus name)|uniprotkb:y1272(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851900|imex:IM-13779-5612	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"refseq:WP_002354507.1|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|go:""GO:0005737""(cytoplasm)|go:""GO:0046872""(metal ion binding)|interpro:IPR036069|refseq:YP_002347645.1|panther:PTHR13799(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	rogid:58ZcDrFPj+OjNZlX9MbsqJHN2vs632	intact-crc:973728501F09BACF|rigid:S60Ym4+8hT0YWrH9kG/wjLFX4I0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZEV7	uniprotkb:Q8NDV7	intact:EBI-2843027|uniprotkb:Q0WFB0	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	psi-mi:syr_yerpe(display_long)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:YPO2046(locus name)|uniprotkb:YP_1889(locus name)|uniprotkb:y2266(locus name)|uniprotkb:argS(gene name)|psi-mi:argS(display_short)	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851918|imex:IM-13779-5616	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|go:""GO:0004814""(arginine-tRNA ligase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006420""(arginyl-tRNA aminoacylation)|refseq:WP_002211212.1|interpro:IPR035684|interpro:IPR036695|refseq:YP_002347028.1|panther:PTHR11956(orthology-group)"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:8Knwt0j/mc9MLObsU71B8vFWs9Y632	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	intact-crc:A47559501ED7F75D|rigid:2Do6Rz2oq0I51QedDc90QpJ9Vjg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5L3C1	uniprotkb:Q8NDV7	intact:EBI-2847786	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	psi-mi:a0a3g5l3c1_yerpe(display_long)|uniprotkb:YP_1852(locus name)|uniprotkb:NCTC5923_03950(orf name)|uniprotkb:y2303(locus name)	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851932|imex:IM-13779-5618	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A6B3T5I1(uniprot-removed-ac)|interpro:IPR025145|refseq:WP_002211249.1	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:frBPrBMI/kR5yM2rqbBIfvX7Eco632	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	intact-crc:1D66598110184F8D|rigid:BGVVIGq4xGF4y8LPejS+g15QCeU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D092	uniprotkb:Q8NDV7	intact:EBI-2845361	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	psi-mi:q8d092_yerpe(display_long)|uniprotkb:fcuA(gene name)|psi-mi:fcuA(display_short)|uniprotkb:y2556(locus name)	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851925|imex:IM-13779-5619	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR010105(TonB-dependent siderophore receptor)|go:""GO:0009279""(cell outer membrane)|go:""GO:0015343""(siderophore-iron transmembrane transporter activity)|go:""GO:0038023""(signaling receptor activity)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:7oNsiLRBKD+1PyrMueBNpf/zdLs632	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	intact-crc:7CA04FEE1FECA8C1|rigid:5Pc4nLh1mrwJ2FpN82uVBWF2Zn4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NDV7	uniprotkb:Q8ZD27	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	intact:EBI-2845155|uniprotkb:Q0WDC5	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	"psi-mi:trua_yerpe(display_long)|uniprotkb:truA(gene name)|psi-mi:truA(display_short)|uniprotkb:tRNA pseudouridylate synthase I(gene name synonym)|uniprotkb:tRNA-uridine isomerase I(gene name synonym)|uniprotkb:YPO2766(locus name)|uniprotkb:y1599(locus name)|uniprotkb:YP_2398(locus name)|uniprotkb:""tRNA pseudouridine(38-40) synthase""(gene name synonym)"	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851911|imex:IM-13779-5615	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"interpro:IPR020103|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020097|interpro:IPR020095|interpro:IPR020094|go:""GO:0003723""(RNA binding)|go:""GO:0009982""(pseudouridine synthase activity)|go:""GO:0031119""(tRNA pseudouridine synthesis)|go:""GO:0160147""(""tRNA pseudouridine(38-40) synthase activity"")|refseq:YP_002347713.1|panther:PTHR11142(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	rogid:a17mT3UwCaK/XvwEwVp22kSNG8U632	intact-crc:CD2C28501EC1BB22|rigid:3yggP5tTGqaU+XbP3mL9CeUO3PU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W3H2	uniprotkb:Q8NDV7	intact:EBI-2851939|uniprotkb:Q74UI4|uniprotkb:A0A380PE32|uniprotkb:Q0WG76|uniprotkb:Q7CIW3|uniprotkb:A0A384K9C1	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	psi-mi:a0a0h2w3h2_yerpe(display_long)|uniprotkb:htrE(gene name)|psi-mi:htrE(display_short)|uniprotkb:YPO1709(locus name)	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851944|imex:IM-13779-5617	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018030|interpro:IPR042186|interpro:IPR000015(Fimbrial biogenesis outer membrane usher protein)|interpro:IPR025885|interpro:IPR025949|refseq:WP_002210844.1|go:""GO:0009279""(cell outer membrane)|go:""GO:0009297""(pilus assembly)|go:""GO:0015473""(fimbrial usher porin activity)|interpro:IPR043142|interpro:IPR037224|refseq:YP_002346712.1"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:UsMKK3JW2vPrcMQUYMARltltJ+A632	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	intact-crc:2AF7F8EF88998D5C|rigid:+EIpZpF6NCVn1KwE2A+fDXgDJ7o	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92956	uniprotkb:Q9RI12	intact:EBI-1056653|uniprotkb:Q6IB95|uniprotkb:Q8WXR1|uniprotkb:Q96J31|uniprotkb:Q9UM65|uniprotkb:B9DI89|uniprotkb:B3KW30|uniprotkb:Q8N634|ensembl:ENSP00000347948.4|ensembl:ENSP00000478308.1	intact:EBI-2849107|uniprotkb:O68717	psi-mi:tnr14_human(display_long)|uniprotkb:TNFRSF14(gene name)|psi-mi:TNFRSF14(display_short)|uniprotkb:HVEA(gene name synonym)|uniprotkb:HVEM(gene name synonym)|uniprotkb:UNQ329/PRO509(orf name)|uniprotkb:Herpes virus entry mediator A(gene name synonym)|uniprotkb:Tumor necrosis factor receptor-like 2(gene name synonym)	psi-mi:ypka_yerpe(display_long)|uniprotkb:ypkA(gene name)|psi-mi:ypkA(display_short)|uniprotkb:Targeted effector protein kinase(gene name synonym)|uniprotkb:YPCD1.72c(locus name)|uniprotkb:y5008(locus name)|uniprotkb:y0009(locus name)|uniprotkb:YP_pCD13(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851988|imex:IM-13779-5622	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003811.2|ensembl:ENSG00000157873.18(gene)|ensembl:ENSG00000273936.4(gene)|ensembl:ENST00000355716.5(transcript)|ensembl:ENST00000621877.3(transcript)|go:""GO:0001618""(virus receptor activity)|go:""GO:0002250""(adaptive immune response)|go:""GO:0002720""(positive regulation of cytokine production involved in immune response)|go:""GO:0005031""(tumor necrosis factor receptor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0019955""(cytokine binding)|go:""GO:0031295""(T cell costimulation)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0045087""(innate immune response)|go:""GO:0046642""(negative regulation of alpha-beta T cell proliferation)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0050830""(defense response to Gram-positive bacterium)|go:""GO:1905675""(negative regulation of adaptive immune memory response)|go:""GO:2000406""(positive regulation of T cell migration)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022332|interpro:IPR034031|mint:Q92956|rcsb pdb:1JMA|rcsb pdb:2AW2|rcsb pdb:4FHQ|rcsb pdb:4RSU|rcsb pdb:5T2Q|rcsb pdb:5T2R|rcsb pdb:6NG3|rcsb pdb:7MSG|reactome:R-HSA-388841|reactome:R-HSA-5669034|refseq:XP_016858209.1|dip:DIP-34779N|panther:PTHR46838(orthology-group)|ensembl:ENSP00000347948.4|ensembl:ENSP00000478308.1"	"refseq:WP_002213290.1|refseq:NP_395206.1|refseq:NP_857776.1|refseq:NP_857907.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR019093|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR003547(Serine/threonine protein kinase, yersinia)|refseq:WP_011114033.1|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR043119|interpro:IPR043120|mint:Q9RI12|panther:PTHR24347(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/20	rogid:h0mNlFr7weiZLHYvGJofgj86y249606	rogid:nPxkaYGmknZ8HLutwXFqE35m9B0632	intact-crc:F3464C205F914C76|rigid:yHKhn2zXUoVT1glMxU7QpNFsKKU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NDV7	uniprotkb:A0A2S9PGH2	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	intact:EBI-2841736|uniprotkb:Q74VC0|uniprotkb:A0A384KX68|uniprotkb:A0A0H2W3K3|uniprotkb:Q7CHQ0	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	psi-mi:a0a2s9pgh2_yerpe(display_long)|uniprotkb:YPO1501(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851951|imex:IM-13779-5620	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"interpro:IPR000801(Putative esterase)|interpro:IPR014186(S-formylglutathione hydrolase)|interpro:IPR029058|go:""GO:0005829""(cytosol)|go:""GO:0018738""(S-formylglutathione hydrolase activity)|go:""GO:0046294""(formaldehyde catabolic process)|go:""GO:0052689""(carboxylic ester hydrolase activity)|refseq:WP_002211956.1|refseq:YP_002346517.1|panther:PTHR10061(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	rogid:FjJgpXBeu1OY0vqJNXuTwaWwJOQ632	intact-crc:DA0EE592C00285B3|rigid:BJCUY5IcKXnj43lWhVB1aXj8cZo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YCV0	uniprotkb:Q8NDV7	intact:EBI-2847775|uniprotkb:Q74Q84|uniprotkb:Q0WIC7|uniprotkb:Q7CGS8|uniprotkb:A0A384L1X8	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	psi-mi:a0a5p8ycv0_yerpe(display_long)|uniprotkb:YPO0913(locus name)	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851958|imex:IM-13779-5621	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|refseq:WP_002209955.1|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0009396""(folic acid-containing compound biosynthetic process)|go:""GO:0030272""(5-formyltetrahydrofolate cyclo-ligase activity)|go:""GO:0035999""(tetrahydrofolate interconversion)|go:""GO:0046872""(metal ion binding)|interpro:IPR024185|interpro:IPR037171|refseq:YP_002345961.1|panther:PTHR23407(orthology-group)"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:10+1hunnZ1E8GkdgkFMuY64dDRY632	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	intact-crc:BD62C1FDB42812A8|rigid:nriJyjDwwQcUdxJ+diVcb5gFij0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJI2	uniprotkb:P20333	intact:EBI-2851979|uniprotkb:Q0WKH7	intact:EBI-358983|uniprotkb:Q16042|uniprotkb:Q6YI29|uniprotkb:Q9UIH1|uniprotkb:B1AJZ3|ensembl:ENSP00000365435.3	psi-mi:malt_yerpe(display_long)|uniprotkb:malT(gene name)|psi-mi:malT(display_short)|uniprotkb:ATP-dependent transcriptional activator MalT(gene name synonym)|uniprotkb:YPO0123(locus name)|uniprotkb:YP_0125(locus name)|uniprotkb:y3900(locus name)	psi-mi:tnr1b_human(display_long)|uniprotkb:TNFRSF1B(gene name)|psi-mi:TNFRSF1B(display_short)|uniprotkb:TNFBR(gene name synonym)|uniprotkb:TNFR2(gene name synonym)|uniprotkb:Tumor necrosis factor receptor 2(gene name synonym)|uniprotkb:Tumor necrosis factor receptor type II(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:p80 TNF-alpha receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851976|imex:IM-13779-5623	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023768|interpro:IPR000792(Bacterial regulatory protein, LuxR)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045913""(positive regulation of carbohydrate metabolic process)|interpro:IPR036388|refseq:WP_002208926.1|refseq:YP_002345211.1|panther:PTHR44688(orthology-group)"	"efo:""Orphanet:2584""|efo:""Orphanet:3162""|ensembl:ENSG00000028137.19(gene)|ensembl:ENST00000376259.7(transcript)|go:""GO:0002718""(regulation of cytokine production involved in immune response)|go:""GO:0002724""(regulation of T cell cytokine production)|go:""GO:0002947""(tumor necrosis factor receptor superfamily complex)|go:""GO:0003176""(aortic valve development)|go:""GO:0003177""(pulmonary valve development)|go:""GO:0003332""(negative regulation of extracellular matrix constituent secretion)|go:""GO:0005031""(tumor necrosis factor receptor activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005886""(plasma membrane)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0008630""(intrinsic apoptotic signaling pathway in response to DNA damage)|go:""GO:0010614""(negative regulation of cardiac muscle hypertrophy)|go:""GO:0016020""(membrane)|go:""GO:0031625""(ubiquitin protein ligase binding)|go:""GO:0031641""(regulation of myelination)|go:""GO:0031643""(positive regulation of myelination)|go:""GO:0033209""(tumor necrosis factor-mediated signaling pathway)|go:""GO:0035579""(specific granule membrane)|go:""GO:0042129""(regulation of T cell proliferation)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043120""(tumor necrosis factor binding)|go:""GO:0043196""(varicosity)|go:""GO:0045121""(membrane raft)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048714""(positive regulation of oligodendrocyte differentiation)|go:""GO:0050779""(RNA destabilization)|go:""GO:0051044""(positive regulation of membrane protein ectodomain proteolysis)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071363""(cellular response to growth factor stimulus)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0150077""(regulation of neuroinflammatory response)|go:""GO:0150079""(negative regulation of neuroinflammatory response)|go:""GO:0150098""(glial cell-neuron signaling)|go:""GO:1902339""(positive regulation of apoptotic process involved in morphogenesis)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR020411|interpro:IPR033996|interpro:IPR051670|mint:P20333|rcsb pdb:1CA9|rcsb pdb:3ALQ|rcsb pdb:8HLB|reactome:R-HSA-5668541|reactome:R-HSA-5669034|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_001057.1|dip:DIP-78N|panther:PTHR47386(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pwBOx98oeu/gM/SCtiq2SiDs4nE632	rogid:j53K3KYEzPRDmeDKcUxqoK7SoGY9606	intact-crc:A13375D75D60C814|rigid:bfAfxTVnXVuV7OehJYaoeJZNn4c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8NDV7	uniprotkb:A0A3N4AZ94	intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|ensembl:ENSP00000379144.3|uniprotkb:C9JAR8	intact:EBI-2851965|uniprotkb:Q74Q42|uniprotkb:Q0WJF5|uniprotkb:Q7CG98|uniprotkb:A0A384LQH9	psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)	psi-mi:a0a3n4az94_yerpe(display_long)|uniprotkb:YPO0510(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2851969|imex:IM-13779-5624	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055309.2|ensembl:ENSG00000090905.19(gene)|ensembl:ENST00000395799.8(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007492""(endoderm development)|go:""GO:0009267""(cellular response to starvation)|go:""GO:0016442""(RISC complex)|go:""GO:0030674""(protein-macromolecule adaptor activity)|go:""GO:0033962""(P-body assembly)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034924|interpro:IPR035979|interpro:IPR052068|mint:Q8NDV7|rcsb pdb:5W6V|rcsb pdb:7RUP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|panther:PTHR13020(orthology-group)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_002214739.1|refseq:YP_002345583.1|interpro:IPR052949|panther:PTHR42999(orthology-group)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/02	rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606	rogid:IAdCH4OmuZuWw6SQpr1rpqPzUIg632	intact-crc:CCBC04927199E620|rigid:cuYied4zozX9Oh/2eSO4d+Wg+KE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q06643	uniprotkb:A0A2U2GZV9	intact:EBI-524217|uniprotkb:P78370|uniprotkb:Q99761|ensembl:ENSP00000365285.3|ensembl:ENSP00000372985.2|ensembl:ENSP00000393693.2|ensembl:ENSP00000395102.2|ensembl:ENSP00000398741.2|ensembl:ENSP00000404014.2|ensembl:ENSP00000404450.2|ensembl:ENSP00000410481.3|uniprotkb:Q52LU8	intact:EBI-2851452|uniprotkb:Q74S60|uniprotkb:Q0WHX5|uniprotkb:Q7CH26|uniprotkb:A0A384LQC5	psi-mi:tnfc_human(display_long)|uniprotkb:Tumor necrosis factor C(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 3(gene name synonym)|uniprotkb:LTB(gene name)|psi-mi:LTB(display_short)|uniprotkb:TNFC(gene name synonym)|uniprotkb:TNFSF3(gene name synonym)	psi-mi:a0a2u2gzv9_yerpe(display_long)|uniprotkb:YPO1069(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852038|imex:IM-13779-5627	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204487.8(gene)|ensembl:ENSG00000206437.10(gene)|ensembl:ENSG00000223448.7(gene)|ensembl:ENSG00000227507.3(gene)|ensembl:ENSG00000231314.7(gene)|ensembl:ENSG00000236237.7(gene)|ensembl:ENSG00000236925.7(gene)|ensembl:ENSG00000238114.7(gene)|ensembl:ENST00000376117.3(transcript)|ensembl:ENST00000383493.2(transcript)|ensembl:ENST00000420402.2(transcript)|ensembl:ENST00000421268.2(transcript)|ensembl:ENST00000429299.3(transcript)|ensembl:ENST00000444479.2(transcript)|ensembl:ENST00000456113.2(transcript)|ensembl:ENST00000457552.2(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0010467""(gene expression)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043588""(skin development)|go:""GO:0048535""(lymph node development)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002961(Tumour necrosis factor c/lymphotoxin-beta)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594|refseq:NP_002332.1|refseq:NP_033666.1|panther:PTHR11471(orthology-group)|dip:DIP-2996N"	"interpro:IPR023368|interpro:IPR023370|refseq:WP_002212157.1|go:""GO:0089715""(""tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity"")|interpro:IPR040372|interpro:IPR036413|interpro:IPR036414|interpro:IPR041369|refseq:YP_002346113.1|panther:PTHR12818(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rf1zq2ooNyfvllGuon3bemfZU549606	rogid:QbU8yYa76G/gWfRLzFass7p1q3Y632	intact-crc:540710337663D0C1|rigid:06W107xBGo7/DOpOi2Gu4rxYWxM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q06643	uniprotkb:Q8ZII0	intact:EBI-524217|uniprotkb:P78370|uniprotkb:Q99761|ensembl:ENSP00000365285.3|ensembl:ENSP00000372985.2|ensembl:ENSP00000393693.2|ensembl:ENSP00000395102.2|ensembl:ENSP00000398741.2|ensembl:ENSP00000404014.2|ensembl:ENSP00000404450.2|ensembl:ENSP00000410481.3|uniprotkb:Q52LU8	intact:EBI-2845275|uniprotkb:Q0WJE7	psi-mi:tnfc_human(display_long)|uniprotkb:Tumor necrosis factor C(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 3(gene name synonym)|uniprotkb:LTB(gene name)|psi-mi:LTB(display_short)|uniprotkb:TNFC(gene name synonym)|uniprotkb:TNFSF3(gene name synonym)	psi-mi:rapa_yerpe(display_long)|uniprotkb:rapA(gene name)|psi-mi:rapA(display_short)|uniprotkb:hepA(gene name synonym)|uniprotkb:YPO0517(locus name)|uniprotkb:y3656(locus name)|uniprotkb:YP_3662(locus name)|uniprotkb:ATP-dependent helicase HepA(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852031|imex:IM-13779-5628	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000204487.8(gene)|ensembl:ENSG00000206437.10(gene)|ensembl:ENSG00000223448.7(gene)|ensembl:ENSG00000227507.3(gene)|ensembl:ENSG00000231314.7(gene)|ensembl:ENSG00000236237.7(gene)|ensembl:ENSG00000236925.7(gene)|ensembl:ENSG00000238114.7(gene)|ensembl:ENST00000376117.3(transcript)|ensembl:ENST00000383493.2(transcript)|ensembl:ENST00000420402.2(transcript)|ensembl:ENST00000421268.2(transcript)|ensembl:ENST00000429299.3(transcript)|ensembl:ENST00000444479.2(transcript)|ensembl:ENST00000456113.2(transcript)|ensembl:ENST00000457552.2(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0010467""(gene expression)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043588""(skin development)|go:""GO:0048535""(lymph node development)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002961(Tumour necrosis factor c/lymphotoxin-beta)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594|refseq:NP_002332.1|refseq:NP_033666.1|panther:PTHR11471(orthology-group)|dip:DIP-2996N"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR023949|interpro:IPR022737|interpro:IPR000330(SNF2-related)|interpro:IPR040765|interpro:IPR040766|interpro:IPR027417|refseq:WP_002220588.1|go:""GO:0003677""(DNA binding)|go:""GO:0003682""(chromatin binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0016817""(hydrolase activity, acting on acid anhydrides)|go:""GO:0031507""(heterochromatin formation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0140750""(nucleosome array spacer activity)|interpro:IPR038718|refseq:YP_002345591.1|interpro:IPR049730|panther:PTHR10799(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:rf1zq2ooNyfvllGuon3bemfZU549606	rogid:aLthHtAzTIsYwrCvth6qDQS+yVs632	intact-crc:9F5B82FF38E57976|rigid:ohZjDeVJNuU06jfv1HfnoPG2nm4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYS8	uniprotkb:Q9NP84	intact:EBI-2848020|uniprotkb:A0A0H2W3W7|uniprotkb:Q74UX2|uniprotkb:Q0WFX0|uniprotkb:Q7CHZ0|uniprotkb:A0A384LK21	intact:EBI-2851995|uniprotkb:Q9HCS0|uniprotkb:D3DUA6|ensembl:ENSP00000326737.5	psi-mi:a0a2u2gys8_yerpe(display_long)|uniprotkb:flaN(gene name)|psi-mi:flaN(display_short)|uniprotkb:fliN(gene name synonym)|uniprotkb:motD(gene name synonym)|uniprotkb:YPO1822(locus name)	psi-mi:tnr12_human(display_long)|uniprotkb:TNFRSF12A(gene name)|psi-mi:TNFRSF12A(display_short)|uniprotkb:FN14(gene name synonym)|uniprotkb:Fibroblast growth factor-inducible immediate-early response protein 14(gene name synonym)|uniprotkb:Tweak-receptor(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852000|imex:IM-13779-5625	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543(""Surface presentation of antigens (SPOA) protein"")|refseq:WP_002211134.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|interpro:IPR031576|interpro:IPR036429|refseq:YP_002346818.1|interpro:IPR051469"	"refseq:NP_057723.1|ensembl:ENSG00000006327.14(gene)|ensembl:ENST00000326577.9(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0007155""(cell adhesion)|go:""GO:0030154""(cell differentiation)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0061041""(regulation of wound healing)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR022316|mint:Q9NP84|rcsb pdb:2EQP|rcsb pdb:2KMZ|rcsb pdb:2RPJ|reactome:R-HSA-5668541|reactome:R-HSA-5676594|panther:PTHR32037(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:tu64Fyw8IQAR2ocM2WNYapEkzHA632	rogid:Dt8beNQk0ZQIvgZNCOWKnMvO/+g9606	intact-crc:DA02D027249B72B2|rigid:pWkiODQZAGth4kaa32dNhCVXw6E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZC49	uniprotkb:Q15025	intact:EBI-2852010|uniprotkb:Q0WCB0	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|ensembl:ENSP00000317891.7|ensembl:ENSP00000428187.1|ensembl:ENSP00000428404.2|ensembl:ENSP00000430279.2|ensembl:ENSP00000430760.1|uniprotkb:B7Z699|uniprotkb:Q6N077|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:thii_yerpe(display_long)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:YPO3173(locus name)|uniprotkb:y1012(locus name)|uniprotkb:YP_0758(locus name)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852007|imex:IM-13779-5626	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026340|interpro:IPR001763(Rhodanese-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|refseq:WP_002208658.1|go:""GO:0000049""(tRNA binding)|go:""GO:0002937""(tRNA 4-thiouridine biosynthesis)|go:""GO:0004810""(CCA tRNA nucleotidyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0052837""(thiazole biosynthetic process)|go:""GO:0140741""(tRNA-uracil-4 sulfurtransferase activity)|interpro:IPR036873|interpro:IPR054173|refseq:YP_002348078.1|interpro:IPR049961|interpro:IPR049962|interpro:IPR050102|panther:PTHR43209(orthology-group)"	"ensembl:ENSG00000145901.17(gene)|ensembl:ENST00000315050.11(transcript)|ensembl:ENST00000520695.6(transcript)|ensembl:ENST00000521001.2(transcript)|ensembl:ENST00000521591.6(transcript)|ensembl:ENST00000522226.5(transcript)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006412""(translation)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0009101""(glycoprotein biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:1903003""(positive regulation of protein deubiquitination)|mint:Q15025|rcsb pdb:7EAL|rcsb pdb:7EAO|rcsb pdb:7EB9|rcsb pdb:8YFK|rcsb pdb:8YFM|rcsb pdb:8YFN|reactome:R-HSA-5689896|refseq:NP_001239314.1|refseq:NP_001239315.1|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:NP_006049.3|refseq:XP_006714814.1|refseq:XP_006714815.1|dip:DIP-27577N|efo:""Orphanet:536""|panther:PTHR31882(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JVdYYtaSxHT0xyr6zYDRPl2jCF4632	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:B06C33CC7DFA28BF|rigid:QOCrlMutU8yuCQyhDcytV1CZ5YA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15025	uniprotkb:A0A5P8YEG1	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|ensembl:ENSP00000317891.7|ensembl:ENSP00000428187.1|ensembl:ENSP00000428404.2|ensembl:ENSP00000430279.2|ensembl:ENSP00000430760.1|uniprotkb:B7Z699|uniprotkb:Q6N077|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-2852022|uniprotkb:Q74UV9|uniprotkb:A0A2U2GXG2|uniprotkb:A0A0H2W3X6|uniprotkb:Q7CHY3|uniprotkb:A0A384KW77	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:a0a5p8yeg1_yerpe(display_long)|uniprotkb:flaS(gene name)|psi-mi:flaS(display_short)|uniprotkb:flaW(gene name synonym)|uniprotkb:flgK(gene name synonym)|uniprotkb:YPO1808(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852019|imex:IM-13779-5629	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000145901.17(gene)|ensembl:ENST00000315050.11(transcript)|ensembl:ENST00000520695.6(transcript)|ensembl:ENST00000521001.2(transcript)|ensembl:ENST00000521591.6(transcript)|ensembl:ENST00000522226.5(transcript)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006412""(translation)|go:""GO:0006952""(defense response)|go:""GO:0006954""(inflammatory response)|go:""GO:0007159""(leukocyte cell-cell adhesion)|go:""GO:0009101""(glycoprotein biosynthetic process)|go:""GO:0042802""(identical protein binding)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0045071""(negative regulation of viral genome replication)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0051019""(mitogen-activated protein kinase binding)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:1903003""(positive regulation of protein deubiquitination)|mint:Q15025|rcsb pdb:7EAL|rcsb pdb:7EAO|rcsb pdb:7EB9|rcsb pdb:8YFK|rcsb pdb:8YFM|rcsb pdb:8YFN|reactome:R-HSA-5689896|refseq:NP_001239314.1|refseq:NP_001239315.1|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:NP_006049.3|refseq:XP_006714814.1|refseq:XP_006714815.1|dip:DIP-27577N|efo:""Orphanet:536""|panther:PTHR31882(orthology-group)"	"interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR002371(Flagellar hook-associated protein)|refseq:WP_002211119.1|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009424""(bacterial-type flagellum hook)|go:""GO:0044780""(bacterial-type flagellum assembly)|interpro:IPR053927|interpro:IPR049119|refseq:YP_002346803.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:pNXjB/cj8ecgLe9j2NLbgGL8sgw632	intact-crc:D535C8B457FE6A3D|rigid:2qqxLhq9w8vE8zX81o4rcueAiWY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P50591	uniprotkb:Q8D0V0	intact:EBI-495373|uniprotkb:A1Y9B3|ensembl:ENSP00000241261.2	intact:EBI-2849272	psi-mi:tnf10_human(display_long)|uniprotkb:TNF-related apoptosis-inducing ligand(gene name synonym)|uniprotkb:Apo-2 ligand(gene name synonym)|uniprotkb:TNFSF10(gene name)|psi-mi:TNFSF10(display_short)|uniprotkb:APO2L(gene name synonym)|uniprotkb:TRAIL(gene name synonym)	psi-mi:q8d0v0_yerpe(display_long)|uniprotkb:fadL(gene name)|psi-mi:fadL(display_short)|uniprotkb:Outer membrane FadL protein(gene name synonym)|uniprotkb:Outer membrane flp protein(gene name synonym)|uniprotkb:y1577(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852045|imex:IM-13779-5630	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_003801.1|refseq:NP_001177871.1|ensembl:ENSG00000121858.11(gene)|ensembl:ENST00000241261.7(transcript)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005164""(tumor necrosis factor receptor binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005886""(plasma membrane)|go:""GO:0006915""(apoptotic process)|go:""GO:0006955""(immune response)|go:""GO:0007165""(signal transduction)|go:""GO:0007166""(cell surface receptor signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0008270""(zinc ion binding)|go:""GO:0008584""(male gonad development)|go:""GO:0032868""(response to insulin)|go:""GO:0036462""(TRAIL-activated apoptotic signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043065""(positive regulation of apoptotic process)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0045569""(TRAIL binding)|go:""GO:0070062""(extracellular exosome)|go:""GO:0090200""(positive regulation of release of cytochrome c from mitochondria)|go:""GO:2001056""(obsolete positive regulation of cysteine-type endopeptidase activity)|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR017355(Tumour necrosis factor ligand superfamily member, 10/11)|interpro:IPR021184|mint:P50591|rcsb pdb:1D0G|rcsb pdb:1D2Q|rcsb pdb:1D4V|rcsb pdb:1DG6|rcsb pdb:1DU3|rcsb pdb:4N90|rcsb pdb:5CIR|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-69416|reactome:R-HSA-75158|dip:DIP-6230N|panther:PTHR11471(orthology-group)"	"interpro:IPR005017(Membrane protein involved in aromatic hydrocarbon degradation)|go:""GO:0006869""(lipid transport)|go:""GO:0009279""(cell outer membrane)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:hnOC/z7IWh8JRE86qlqUdVvNDUM9606	rogid:t3ttYDBykbAjdOq/JpJE2QGeyvk632	intact-crc:311624BEDFACE27E|rigid:GNCJbcengI+/BelYa3bcYpW4H08	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D054	uniprotkb:Q9UPQ9	intact:EBI-2852052	intact:EBI-947158|uniprotkb:B0QY78|uniprotkb:Q5TH52|uniprotkb:Q8TBX2|uniprotkb:B4DGC0|uniprotkb:B0QY73|ensembl:ENSP00000401946.2	psi-mi:q8d054_yerpe(display_long)|uniprotkb:fabF(gene name)|psi-mi:fabF(display_short)|uniprotkb:fabF_4(gene name synonym)|uniprotkb:NCTC5923_01694(orf name)|uniprotkb:y2744(locus name)	psi-mi:tnr6b_human(display_long)|uniprotkb:TNRC6B(gene name)|psi-mi:TNRC6B(display_short)|uniprotkb:KIAA1093(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852056|imex:IM-13779-5631	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018201|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016039(Thiolase-like)|interpro:IPR020841|go:""GO:0004315""(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:""GO:0006633""(fatty acid biosynthetic process)|interpro:IPR000794(Beta-ketoacyl synthase)"	"ensembl:ENSG00000100354.22(gene)|ensembl:ENST00000454349.7(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034925|interpro:IPR035979|interpro:IPR052068|mint:Q9UPQ9|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001020014.1|refseq:NP_001155973.1|refseq:NP_055903.2|dip:DIP-29624N|efo:""Orphanet:528084""|panther:PTHR13020(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xl43YLev9BwgHiphq3Wzri47FxA632	rogid:A4yGG9Gt++0QN+6jFzfhWVYN+Dw9606	intact-crc:E10204ACDAB087D8|rigid:6uzpaTZqIYhaNYY+5klOuI0FVmY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UPQ9	uniprotkb:A0A5P8YBY1	intact:EBI-947158|uniprotkb:B0QY78|uniprotkb:Q5TH52|uniprotkb:Q8TBX2|uniprotkb:B4DGC0|uniprotkb:B0QY73|ensembl:ENSP00000401946.2	intact:EBI-2852073|uniprotkb:Q74X31|uniprotkb:Q7CKG1|uniprotkb:Q0WBJ5	psi-mi:tnr6b_human(display_long)|uniprotkb:TNRC6B(gene name)|psi-mi:TNRC6B(display_short)|uniprotkb:KIAA1093(gene name synonym)	psi-mi:a0a5p8yby1_yerpe(display_long)|uniprotkb:nrdD(gene name)|psi-mi:nrdD(display_short)|uniprotkb:YPO3454(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852070|imex:IM-13779-5633	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000100354.22(gene)|ensembl:ENST00000454349.7(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034925|interpro:IPR035979|interpro:IPR052068|mint:Q9UPQ9|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001020014.1|refseq:NP_001155973.1|refseq:NP_055903.2|dip:DIP-29624N|efo:""Orphanet:528084""|panther:PTHR13020(orthology-group)"	"interpro:IPR001150(Formate C-acetyltransferase glycine radical)|interpro:IPR019777|interpro:IPR005144(ATP-cone)|interpro:IPR012833(Ribonucleoside-triphosphate reductase, anaerobic)|go:""GO:0005524""(ATP binding)|go:""GO:0006260""(DNA replication)|go:""GO:0008998""(""ribonucleoside-triphosphate reductase (thioredoxin) activity"")|go:""GO:0009265""(2'-deoxyribonucleotide biosynthetic process)|go:""GO:0031250""(anaerobic ribonucleoside-triphosphate reductase complex)|refseq:WP_002209296.1|refseq:YP_002348343.1|panther:PTHR21075(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:A4yGG9Gt++0QN+6jFzfhWVYN+Dw9606	rogid:7LnLLa9YGnbuC68urjasHfsbkSM632	intact-crc:F6B387F90EC8EFFA|rigid:2MOLx5wwJWb3eKZp0waJmiiB9to	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D050	uniprotkb:Q9UPQ9	intact:EBI-2848540|uniprotkb:Q74VU3	intact:EBI-947158|uniprotkb:B0QY78|uniprotkb:Q5TH52|uniprotkb:Q8TBX2|uniprotkb:B4DGC0|uniprotkb:B0QY73|ensembl:ENSP00000401946.2	psi-mi:q8d050_yerpe(display_long)|uniprotkb:aspC(gene name)|psi-mi:aspC(display_short)|uniprotkb:y2760(locus name)|uniprotkb:YP_1183(locus name)	psi-mi:tnr6b_human(display_long)|uniprotkb:TNRC6B(gene name)|psi-mi:TNRC6B(display_short)|uniprotkb:KIAA1093(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852063|imex:IM-13779-5634	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)"	"ensembl:ENSG00000100354.22(gene)|ensembl:ENST00000454349.7(transcript)|go:""GO:0000932""(P-body)|go:""GO:0003723""(RNA binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0031047""(regulatory ncRNA-mediated gene silencing)|go:""GO:0035195""(miRNA-mediated post-transcriptional gene silencing)|go:""GO:0035278""(miRNA-mediated gene silencing by inhibition of translation)|go:""GO:0060213""(""positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"")|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR034925|interpro:IPR035979|interpro:IPR052068|mint:Q9UPQ9|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9759811|reactome:R-HSA-9768778|reactome:R-HSA-9824594|reactome:R-HSA-9839394|refseq:NP_001020014.1|refseq:NP_001155973.1|refseq:NP_055903.2|dip:DIP-29624N|efo:""Orphanet:528084""|panther:PTHR13020(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:PXhfATAXvq73Z2dQc+YovYvMWRY632	rogid:A4yGG9Gt++0QN+6jFzfhWVYN+Dw9606	intact-crc:550204ACDBC37A3D|rigid:QiIDuYOaBMyiKdwB5cs+9Ge8Efo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P21580	uniprotkb:Q8ZA88	intact:EBI-527670|uniprotkb:Q9NSR6|uniprotkb:Q2HIX9|uniprotkb:Q5VXQ7|uniprotkb:B2R767|uniprotkb:E1P588|ensembl:ENSP00000237289.4|ensembl:ENSP00000393577.2|ensembl:ENSP00000401562.2|ensembl:ENSP00000409845.2|ensembl:ENSP00000481570.1	intact:EBI-2852085|uniprotkb:Q0WA90	psi-mi:tnap3_human(display_long)|uniprotkb:Putative DNA-binding protein A20(gene name synonym)|uniprotkb:Zinc finger protein A20(gene name synonym)|uniprotkb:TNFAIP3(gene name)|psi-mi:TNFAIP3(display_short)|uniprotkb:OTUD7C(gene name synonym)|uniprotkb:OTU domain-containing protein 7C(gene name synonym)	psi-mi:arly_yerpe(display_long)|uniprotkb:argH(gene name)|psi-mi:argH(display_short)|uniprotkb:Arginosuccinase(gene name synonym)|uniprotkb:YPO3924(locus name)|uniprotkb:y0312(locus name)|uniprotkb:YP_3125(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852082|imex:IM-13779-5632	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-33804N|efo:""Orphanet:674762""|ensembl:ENSG00000118503.18(gene)|ensembl:ENST00000237289.8(transcript)|ensembl:ENST00000420009.6(transcript)|ensembl:ENST00000421450.2(transcript)|ensembl:ENST00000433680.2(transcript)|ensembl:ENST00000612899.5(transcript)|go:""GO:0001922""(B-1 B cell homeostasis)|go:""GO:0002020""(protease binding)|go:""GO:0002237""(response to molecule of bacterial origin)|go:""GO:0002634""(regulation of germinal center formation)|go:""GO:0002677""(negative regulation of chronic inflammatory response)|go:""GO:0003677""(DNA binding)|go:""GO:0004842""(ubiquitin-protein transferase activity)|go:""GO:0004843""(cysteine-type deubiquitinase activity)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005829""(cytosol)|go:""GO:0006915""(apoptotic process)|go:""GO:0006954""(inflammatory response)|go:""GO:0007010""(cytoskeleton organization)|go:""GO:0008270""(zinc ion binding)|go:""GO:0010803""(regulation of tumor necrosis factor-mediated signaling pathway)|go:""GO:0016477""(cell migration)|go:""GO:0016579""(protein deubiquitination)|go:""GO:0019900""(kinase binding)|go:""GO:0030177""(positive regulation of Wnt signaling pathway)|go:""GO:0031397""(negative regulation of protein ubiquitination)|go:""GO:0032088""(negative regulation of NF-kappaB transcription factor activity)|go:""GO:0032495""(response to muramyl dipeptide)|go:""GO:0032691""(negative regulation of interleukin-1 beta production)|go:""GO:0032703""(negative regulation of interleukin-2 production)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0034136""(negative regulation of toll-like receptor 2 signaling pathway)|go:""GO:0034140""(negative regulation of toll-like receptor 3 signaling pathway)|go:""GO:0034144""(negative regulation of toll-like receptor 4 signaling pathway)|go:""GO:0034148""(negative regulation of toll-like receptor 5 signaling pathway)|go:""GO:0035871""(protein K11-linked deubiquitination)|go:""GO:0035872""(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:""GO:0042802""(identical protein binding)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043130""(ubiquitin binding)|go:""GO:0045732""(positive regulation of protein catabolic process)|go:""GO:0045779""(negative regulation of bone resorption)|go:""GO:0045824""(negative regulation of innate immune response)|go:""GO:0048662""(negative regulation of smooth muscle cell proliferation)|go:""GO:0050691""(regulation of defense response to virus by host)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0050869""(negative regulation of B cell activation)|go:""GO:0061043""(regulation of vascular wound healing)|go:""GO:0061578""(K63-linked deubiquitinase activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070301""(cellular response to hydrogen peroxide)|go:""GO:0070429""(negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:""GO:0070433""(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070530""(K63-linked polyubiquitin modification-dependent protein binding)|go:""GO:0070536""(protein K63-linked deubiquitination)|go:""GO:0070936""(protein K48-linked ubiquitination)|go:""GO:0071108""(protein K48-linked deubiquitination)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071947""(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:""GO:0072573""(tolerance induction to lipopolysaccharide)|go:""GO:0072666""(establishment of protein localization to vacuole)|go:""GO:0090291""(negative regulation of osteoclast proliferation)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:2000347""(positive regulation of hepatocyte proliferation)|go:""GO:2000349""(negative regulation of CD40 signaling pathway)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR051346|mint:P21580|rcsb pdb:2EQE|rcsb pdb:2EQF|rcsb pdb:2EQG|rcsb pdb:2VFJ|rcsb pdb:3DKB|rcsb pdb:3OJ3|rcsb pdb:3OJ4|rcsb pdb:3VUW|rcsb pdb:3VUX|rcsb pdb:3VUY|rcsb pdb:3ZJD|rcsb pdb:3ZJE|rcsb pdb:3ZJF|rcsb pdb:3ZJG|rcsb pdb:5LRX|rcsb pdb:5V3B|rcsb pdb:5V3P|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689896|reactome:R-HSA-936440|refseq:NP_001257436.1|refseq:NP_001257437.1|refseq:NP_006281.1|refseq:XP_005267176.1|refseq:XP_011534397.1|efo:""Orphanet:536""|panther:PTHR13367(orthology-group)|ensembl:ENSP00000237289.4|ensembl:ENSP00000401562.2|ensembl:ENSP00000393577.2|ensembl:ENSP00000409845.2|ensembl:ENSP00000481570.1"	"interpro:IPR009049(Argininosuccinate lyase)|interpro:IPR000362(Fumarate lyase)|interpro:IPR020557|interpro:IPR008948(L-Aspartase-like)|interpro:IPR022761|interpro:IPR024083|interpro:IPR029419|refseq:WP_002209487.1|go:""GO:0004056""(argininosuccinate lyase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0042450""(L-arginine biosynthetic process via ornithine)|refseq:YP_002348798.1|panther:PTHR43814(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/26	rogid:+D5JkFvXGge36r13YBqkpk99DLo9606	rogid:nVJsBbhdxEcZqlcuj4AISWxSNcU632	intact-crc:8559AEF0A30CF75A|rigid:pSy98uWWYwuERjs28mxZm/giGmA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B6K1	uniprotkb:Q6UX65	intact:EBI-2841967|uniprotkb:Q7CHV2|uniprotkb:Q0WG31	intact:EBI-2852115|uniprotkb:Q4VWF6|uniprotkb:Q86VD3|uniprotkb:B3SUG9|uniprotkb:Q8NBQ4|ensembl:ENSP00000286692.4|ensembl:ENSP00000437718.1|ensembl:ENSP00000503400.1	psi-mi:a0a3n4b6k1_yerpe(display_long)|uniprotkb:EIIAB-Man(gene name synonym)|uniprotkb:gptB(gene name)|psi-mi:gptB(display_short)|uniprotkb:EIII-Man(gene name synonym)|uniprotkb:manX(gene name synonym)|uniprotkb:ptsL(gene name synonym)|uniprotkb:YPO1758(locus name)	psi-mi:dram2_human(display_long)|uniprotkb:DRAM2(gene name)|psi-mi:DRAM2(display_short)|uniprotkb:TMEM77(gene name synonym)|uniprotkb:Transmembrane protein 77(gene name synonym)|uniprotkb:PSEC0031(orf name)|uniprotkb:UNQ154/PRO180(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852112|imex:IM-13779-5638	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004701(Phosphotransferase system, fructose subfamily IIA component)|interpro:IPR013789(Phosphotransferase system, fructose subfamily IIA component, subgroup)|interpro:IPR004720(Phosphotransferase system, sorbose subfamily IIB component)|interpro:IPR018455|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0016301""(kinase activity)|interpro:IPR033887|interpro:IPR036662|interpro:IPR036667|refseq:WP_002211069.1|refseq:YP_002346757.1|interpro:IPR051471|panther:PTHR33799(orthology-group)"	"ensembl:ENSG00000156171.15(gene)|ensembl:ENST00000286692.8(transcript)|ensembl:ENST00000484310.6(transcript)|ensembl:ENST00000539140.6(transcript)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006914""(autophagy)|go:""GO:0006915""(apoptotic process)|go:""GO:0007601""(visual perception)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045494""(photoreceptor cell maintenance)|go:""GO:0060041""(retina development in camera-type eye)|interpro:IPR019402|interpro:IPR050911|refseq:NP_848549.3|refseq:XP_005270526.1|refseq:XP_005270527.1|refseq:XP_011539009.1|refseq:XP_011539010.1|efo:""Orphanet:1872""|panther:PTHR21324(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6EMnus36OolbaozHpfdN+4jAtF0632	rogid:U+8JsHFoXuLpAUovHL+CyZRyCSg9606	intact-crc:66A3F2E4A38C0343|rigid:1t2HSKfcRQPBeZ5uASfFYFMi7KQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A6B3VCW6	uniprotkb:Q96BY9	intact:EBI-2846132	intact:EBI-722561|uniprotkb:Q53HE8|uniprotkb:Q9UNZ3|uniprotkb:Q9Y683|uniprotkb:D3DSU7|uniprotkb:B3KQQ4|uniprotkb:B7Z9J1|uniprotkb:H9MHJ8|uniprotkb:H9MHJ9|ensembl:ENSP00000256255.6	psi-mi:a0a6b3vcw6_yerpe(display_long)|uniprotkb:YP_3785(locus name)|uniprotkb:y3786(locus name)|uniprotkb:sbcC3(gene name)|psi-mi:sbcC3(display_short)	psi-mi:saraf_human(display_long)|uniprotkb:SARAF(gene name)|psi-mi:SARAF(display_short)|uniprotkb:HBV X-transactivated gene 3 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 3(gene name synonym)|uniprotkb:Protein FOAP-7(gene name synonym)|uniprotkb:TMEM66(gene name synonym)|uniprotkb:Transmembrane protein 66(gene name synonym)|uniprotkb:XTP3(gene name synonym)|uniprotkb:HSPC035(orf name)|uniprotkb:NPD003(orf name)|uniprotkb:PSEC0019(orf name)|uniprotkb:UNQ1967/PRO4499(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852134|imex:IM-13779-5636	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:Q8CKB6(uniprot-removed-ac)|refseq:WP_002209173.1|interpro:IPR027417	"refseq:NP_001271168.1|refseq:NP_057211.4|ensembl:ENSG00000133872.14(gene)|ensembl:ENST00000256255.11(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0140268""(endoplasmic reticulum-plasma membrane contact site)|go:""GO:2001256""(regulation of store-operated calcium entry)|interpro:IPR009567(Protein of unknown function DUF1183)|mint:Q96BY9|rcsb pdb:6O2U|rcsb pdb:6O2V|rcsb pdb:6O2W|panther:PTHR15929(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JAJQ2/SqTxwkVfzJ9zXmGfJ8osk632	rogid:qxgObw0slMLCKeF+2YAHTxjlkQk9606	intact-crc:87F8F9220B1C2503|rigid:PM6Y+k+SB7CjEFz8LWD1+moCfKk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5LJH8	uniprotkb:Q6UX65	intact:EBI-2851477|uniprotkb:Q74YN1|uniprotkb:Q7ARE0|uniprotkb:Q7BT25|uniprotkb:A0A384KBQ0|uniprotkb:Q65AN4|uniprotkb:A0A1U8QEQ2|uniprotkb:A0A2U2H125|uniprotkb:O68752	intact:EBI-2852115|uniprotkb:Q4VWF6|uniprotkb:Q86VD3|uniprotkb:B3SUG9|uniprotkb:Q8NBQ4|ensembl:ENSP00000286692.4|ensembl:ENSP00000437718.1|ensembl:ENSP00000503400.1	psi-mi:a0a3g5ljh8_yerpe(display_long)|uniprotkb:YPMT1.34(locus name)	psi-mi:dram2_human(display_long)|uniprotkb:DRAM2(gene name)|psi-mi:DRAM2(display_short)|uniprotkb:TMEM77(gene name synonym)|uniprotkb:Transmembrane protein 77(gene name synonym)|uniprotkb:PSEC0031(orf name)|uniprotkb:UNQ154/PRO180(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852127|imex:IM-13779-5637	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:NP_395372.1|refseq:YP_093913.1|refseq:NP_857671.1|refseq:WP_002211799.1	"ensembl:ENSG00000156171.15(gene)|ensembl:ENST00000286692.8(transcript)|ensembl:ENST00000484310.6(transcript)|ensembl:ENST00000539140.6(transcript)|go:""GO:0001917""(photoreceptor inner segment)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006914""(autophagy)|go:""GO:0006915""(apoptotic process)|go:""GO:0007601""(visual perception)|go:""GO:0008283""(cell population proliferation)|go:""GO:0010506""(regulation of autophagy)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045494""(photoreceptor cell maintenance)|go:""GO:0060041""(retina development in camera-type eye)|interpro:IPR019402|interpro:IPR050911|refseq:NP_848549.3|refseq:XP_005270526.1|refseq:XP_005270527.1|refseq:XP_011539009.1|refseq:XP_011539010.1|efo:""Orphanet:1872""|panther:PTHR21324(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:EQfeZsF+Ifz/4ATGhKSB5pDt9HU632	rogid:U+8JsHFoXuLpAUovHL+CyZRyCSg9606	intact-crc:CCCBCE09B1ED9426|rigid:15y+LJ38QhKfsjsBLdA+9sMPYJ8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8N394	uniprotkb:A0A0H2W5B3	intact:EBI-2852099|uniprotkb:Q8N2K8|uniprotkb:B2RCU7|ensembl:ENSP00000322300.3	intact:EBI-2852094|uniprotkb:Q74US2|uniprotkb:A0A3N4BGG1|uniprotkb:Q0WG25|uniprotkb:Q7CHV7|uniprotkb:A0A384LL75	psi-mi:tmtc2_human(display_long)|uniprotkb:TMTC2(gene name)|psi-mi:TMTC2(display_short)|uniprotkb:Transmembrane O-mannosyltransferase targeting cadherins 2(gene name synonym)|uniprotkb:Transmembrane and tetratricopeptide repeat-containing 2(gene name synonym)	psi-mi:a0a0h2w5b3_yerpe(display_long)|uniprotkb:hpaH(gene name)|psi-mi:hpaH(display_short)|uniprotkb:hpcG(gene name synonym)|uniprotkb:YPO1766(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852105|imex:IM-13779-5635	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_689801.1|refseq:NP_001307250.1|ensembl:ENSG00000179104.9(gene)|ensembl:ENST00000321196.8(transcript)|go:""GO:0000030""(mannosyltransferase activity)|go:""GO:0004169""(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0035269""(protein O-linked mannosylation)|go:""GO:0055074""(calcium ion homeostasis)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013618(Region of unknown function DUF1736)|interpro:IPR019734|interpro:IPR052384|mint:Q8N394|panther:PTHR44216(orthology-group)"	"interpro:IPR012690(2-oxo-hepta-3-ene-1,7-dioic acid hydratase)|refseq:WP_002211074.1|go:""GO:0009056""(catabolic process)|go:""GO:0018817""(2-oxo-hept-3-ene-1,7-dioate hydratase activity)|interpro:IPR036663|refseq:YP_002346763.1|interpro:IPR050772|interpro:IPR011234(Fumarylacetoacetase, C-terminal-related)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/ZbeUiq2aqzLDEGo3lsf/FyyKwc9606	rogid:51nRlHF8JkFhYaUo6oPpqkEY8Ug632	intact-crc:2661306444984B5F|rigid:EBbQZDkxF8Hey80kubuApukjU2U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W8E2	uniprotkb:Q96BY9	intact:EBI-2845898|uniprotkb:Q74Q33|uniprotkb:Q0WJG5|uniprotkb:Q7CG91|uniprotkb:A0A2U2H085|uniprotkb:A0A384KB95	intact:EBI-722561|uniprotkb:Q53HE8|uniprotkb:Q9UNZ3|uniprotkb:Q9Y683|uniprotkb:D3DSU7|uniprotkb:B3KQQ4|uniprotkb:B7Z9J1|uniprotkb:H9MHJ8|uniprotkb:H9MHJ9|ensembl:ENSP00000256255.6	psi-mi:a0a0h2w8e2_yerpe(display_long)|uniprotkb:YPO0500(locus name)	psi-mi:saraf_human(display_long)|uniprotkb:SARAF(gene name)|psi-mi:SARAF(display_short)|uniprotkb:HBV X-transactivated gene 3 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 3(gene name synonym)|uniprotkb:Protein FOAP-7(gene name synonym)|uniprotkb:TMEM66(gene name synonym)|uniprotkb:Transmembrane protein 66(gene name synonym)|uniprotkb:XTP3(gene name synonym)|uniprotkb:HSPC035(orf name)|uniprotkb:NPD003(orf name)|uniprotkb:PSEC0019(orf name)|uniprotkb:UNQ1967/PRO4499(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852141|imex:IM-13779-5639	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR008312(Uncharacterised conserved protein UCP028301)|refseq:WP_002210481.1|refseq:YP_002345573.1	"refseq:NP_001271168.1|refseq:NP_057211.4|ensembl:ENSG00000133872.14(gene)|ensembl:ENST00000256255.11(transcript)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0006816""(calcium ion transport)|go:""GO:0140268""(endoplasmic reticulum-plasma membrane contact site)|go:""GO:2001256""(regulation of store-operated calcium entry)|interpro:IPR009567(Protein of unknown function DUF1183)|mint:Q96BY9|rcsb pdb:6O2U|rcsb pdb:6O2V|rcsb pdb:6O2W|panther:PTHR15929(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:r1UlnEbb/K20reicDTxy4VHlP90632	rogid:qxgObw0slMLCKeF+2YAHTxjlkQk9606	intact-crc:6565E194FF968F9F|rigid:2XQk5cZJCPgUHgQ7JfhCMqopNsg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P17778	uniprotkb:Q9H2L4	intact:EBI-2842665|uniprotkb:O68701	intact:EBI-2852148|uniprotkb:Q86UM0|uniprotkb:A4D1C3|ensembl:ENSP00000257663.3	psi-mi:yopm_yerpe(display_long)|uniprotkb:yopM(gene name)|psi-mi:yopM(display_short)|uniprotkb:yop48(gene name synonym)|uniprotkb:YPCD1.26c(locus name)|uniprotkb:y5054(locus name)|uniprotkb:y0059(locus name)|uniprotkb:YP_pCD60(locus name)	psi-mi:tmm60_human(display_long)|uniprotkb:TMEM60(gene name)|psi-mi:TMEM60(display_short)|uniprotkb:C7orf35(gene name synonym)|uniprotkb:DC32(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852154|imex:IM-13779-5640	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_395161.1|refseq:NP_857756.1|refseq:NP_857953.1|interpro:IPR001611(Leucine-rich repeat)|rcsb pdb:1G9U|rcsb pdb:1JL5|interpro:IPR032674|interpro:IPR032675|refseq:WP_002229779.1|go:""GO:0005576""(extracellular region)|go:""GO:0009279""(cell outer membrane)|go:""GO:0046872""(metal ion binding)|interpro:IPR051071"	"refseq:NP_116325.1|ensembl:ENSG00000135211.6(gene)|ensembl:ENST00000257663.4(transcript)|go:""GO:0016020""(membrane)|interpro:IPR019396|panther:PTHR13568(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:VGxioGI9WPZVr6VnYk8JZlfyPNQ632	rogid:+CJ5JN2+Al51miHdrXGa18mXM089606	intact-crc:EBD3303F12B2B4D6|rigid:Rr/IIPnxuRrzIK8E4opj2nUFhD0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0H8	uniprotkb:Q96GC9	intact:EBI-2851077|uniprotkb:Q74TS0	intact:EBI-2800296|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291.3|ensembl:ENSP00000465397.2|ensembl:ENSP00000466511.2|uniprotkb:B4DVV9	psi-mi:q8d0h8_yerpe(display_long)|uniprotkb:y2119(locus name)|uniprotkb:amn(gene name)|psi-mi:amn(display_short)|uniprotkb:YP_2074(locus name)	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852161|imex:IM-13779-5643	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011271(AMP nucleosidase)|interpro:IPR018953|interpro:IPR000845(Nucleoside phosphorylase)|go:""GO:0008714""(AMP nucleosidase activity)|go:""GO:0009116""(nucleoside metabolic process)|go:""GO:0044209""(AMP salvage)|interpro:IPR035994|interpro:IPR037109|interpro:IPR047039"	"refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716.13(gene)|ensembl:ENST00000262291.9(transcript)|ensembl:ENST00000587259.6(transcript)|ensembl:ENST00000591315.6(transcript)|go:""GO:0000045""(autophagosome assembly)|go:""GO:0000407""(phagophore assembly site)|go:""GO:0000421""(autophagosome membrane)|go:""GO:0005730""(nucleolus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005886""(plasma membrane)|go:""GO:0006914""(autophagy)|go:""GO:0007030""(Golgi organization)|go:""GO:0007566""(embryo implantation)|go:""GO:0012505""(endomembrane system)|go:""GO:0016020""(membrane)|go:""GO:0016240""(autophagosome membrane docking)|go:""GO:0017128""(phospholipid scramblase activity)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034329""(cell junction assembly)|go:""GO:0042953""(lipoprotein transport)|go:""GO:0098609""(cell-cell adhesion)|go:""GO:0140056""(organelle localization by membrane tethering)|go:""GO:1901896""(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:""GO:1990456""(mitochondrion-endoplasmic reticulum membrane tethering)|mint:Q96GC9|panther:PTHR10281(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:pQne2oycJKd7ymLLAwCsL1/6V8U632	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	intact-crc:9874B82B16DE313D|rigid:IHoja/ce/Bfq3pGmxZD1735gTcU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W496	uniprotkb:P82094	intact:EBI-2840791|uniprotkb:Q74VI5|uniprotkb:Q0WHE4|uniprotkb:Q7CHC7|uniprotkb:A0A380PNP6	intact:EBI-949763|uniprotkb:Q17R87|uniprotkb:B7ZLJ2|uniprotkb:Q59GK0|ensembl:ENSP00000381567.2	psi-mi:a0a0h2w496_yerpe(display_long)|uniprotkb:YPO1265(locus name)	psi-mi:tmf1_human(display_long)|uniprotkb:TMF1(gene name)|psi-mi:TMF1(display_short)|uniprotkb:Androgen receptor coactivator 160 kDa protein(gene name synonym)|uniprotkb:ARA160(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 160 kDa(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852180|imex:IM-13779-5641	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011332(Ribosomal protein, zinc-binding)|refseq:YP_002346294.1|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006412""(translation)|go:""GO:0016787""(hydrolase activity)|refseq:WP_002208833.1|interpro:IPR050742"	"refseq:NP_009045.2|refseq:XP_011532358.1|dip:DIP-5933N|ensembl:ENSG00000144747.17(gene)|ensembl:ENST00000398559.7(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001675""(acrosome assembly)|go:""GO:0001819""(positive regulation of cytokine production)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005829""(cytosol)|go:""GO:0007289""(spermatid nucleus differentiation)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0030317""(flagellated sperm motility)|go:""GO:0030374""(obsolete nuclear receptor coactivator activity)|go:""GO:0030521""(androgen receptor signaling pathway)|go:""GO:0032275""(luteinizing hormone secretion)|go:""GO:0033327""(Leydig cell differentiation)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0050681""(nuclear androgen receptor binding)|go:""GO:0061136""(regulation of proteasomal protein catabolic process)|go:""GO:1904019""(epithelial cell apoptotic process)|go:""GO:1904036""(negative regulation of epithelial cell apoptotic process)|go:""GO:2000845""(positive regulation of testosterone secretion)|interpro:IPR022091|interpro:IPR022092|interpro:IPR052602|mint:P82094|reactome:R-HSA-6811440|panther:PTHR46515(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:t0Zbf80G8FGwpaL2FZRae4laaiw632	rogid:F+z+GIH0PWbFoueklDHM/lj55MI9606	intact-crc:604CD02BE3617C90|rigid:AfCvG6keXv/lEt8E59IT6zeOs3Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P57088	uniprotkb:Q8ZC32	intact:EBI-1048629|uniprotkb:Q9H953|uniprotkb:B3KSS8|ensembl:ENSP00000422473.1|ensembl:ENSP00000427006.1	intact:EBI-2852171|uniprotkb:Q0WC91	psi-mi:tmm33_human(display_long)|uniprotkb:Protein DB83(gene name synonym)|uniprotkb:TMEM33(gene name)|psi-mi:TMEM33(display_short)|uniprotkb:DB83(gene name synonym)|uniprotkb:SHINC-3(gene name synonym)	psi-mi:quea_yerpe(display_long)|uniprotkb:queA(gene name)|psi-mi:queA(display_short)|uniprotkb:Queuosine biosynthesis protein QueA(gene name synonym)|uniprotkb:YPO3192(locus name)|uniprotkb:y0990(locus name)|uniprotkb:YP_0739(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852168|imex:IM-13779-5642	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_060596.2|ensembl:ENSG00000109133.14(gene)|ensembl:ENST00000504986.6(transcript)|ensembl:ENST00000513702.5(transcript)|go:""GO:0005635""(nuclear envelope)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0034976""(response to endoplasmic reticulum stress)|go:""GO:0042470""(melanosome)|go:""GO:0045087""(innate immune response)|go:""GO:0061024""(membrane organization)|go:""GO:0071786""(endoplasmic reticulum tubular network organization)|go:""GO:1903371""(regulation of endoplasmic reticulum tubular network organization)|go:""GO:1903896""(positive regulation of IRE1-mediated unfolded protein response)|go:""GO:1903899""(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR005344(Protein of unknown function UPF0121)|interpro:IPR051645|mint:P57088|refseq:XP_005248173.1|refseq:XP_005248174.1|panther:PTHR12703(orthology-group)"	"interpro:IPR003699(Queuosine biosynthesis protein)|refseq:WP_002208673.1|go:""GO:0002099""(tRNA wobble guanine modification)|go:""GO:0005737""(cytoplasm)|go:""GO:0008616""(queuosine biosynthetic process)|go:""GO:0051075""(""S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"")|interpro:IPR036100|interpro:IPR042118|interpro:IPR042119|refseq:YP_002348097.1|panther:PTHR30307(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FGc4/gpnYoRtlDJMxQWh5hXe5Ko9606	rogid:F+PRsjhaH3dz6Fk0kbG+UQpfEYY632	intact-crc:D36F917EE8F99442|rigid:YW/ivReRbndicekJa/yBzDVx+qA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CG87	uniprotkb:Q9HD45	intact:EBI-2852227|uniprotkb:Q74Q29	intact:EBI-2814047|uniprotkb:Q9NWL8|uniprotkb:Q5TB57|uniprotkb:Q9UHW8|uniprotkb:Q6UWE7|uniprotkb:Q9P0G9|ensembl:ENSP00000360184.4	psi-mi:sura_yerpe(display_long)|uniprotkb:surA(gene name)|psi-mi:surA(display_short)|uniprotkb:Peptidyl-prolyl cis-trans isomerase SurA(gene name synonym)|uniprotkb:Rotamase SurA(gene name synonym)|uniprotkb:YPO0494(locus name)|uniprotkb:YP_3685(locus name)|uniprotkb:y3681(locus name)	psi-mi:tm9s3_human(display_long)|uniprotkb:TM9SF3(gene name)|psi-mi:TM9SF3(display_short)|uniprotkb:SMBP(gene name synonym)|uniprotkb:EP70-P-iso(gene name synonym)|uniprotkb:SM-11044-binding protein(gene name synonym)|uniprotkb:UNQ245/PRO282(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852232|imex:IM-13779-5646	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR027304|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR023034|interpro:IPR015391(SurA N-terminal domain)|refseq:WP_002210488.1|go:""GO:0006457""(protein folding)|go:""GO:0030288""(outer membrane-bounded periplasmic space)|go:""GO:0042277""(peptide binding)|go:""GO:0043165""(Gram-negative-bacterium-type cell outer membrane assembly)|go:""GO:0050821""(protein stabilization)|go:""GO:0051082""(unfolded protein binding)|go:""GO:0140839""(RNA polymerase II CTD heptapeptide repeat P3 isomerase activity)|go:""GO:0140840""(RNA polymerase II CTD heptapeptide repeat P6 isomerase activity)|refseq:YP_002345567.1|interpro:IPR050280|interpro:IPR046357|panther:PTHR47637(orthology-group)"	"refseq:NP_064508.3|ensembl:ENSG00000077147.16(gene)|ensembl:ENST00000371142.9(transcript)|go:""GO:0016020""(membrane)|go:""GO:0072657""(protein localization to membrane)|interpro:IPR004240(""Nonaspanin (TM9SF)"")|mint:Q9HD45|panther:PTHR10766(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:5pR5Lwo/ED4KYYhzzIz/G4h13Qg632	rogid:/9Z/a+36wE2FTbIyQ/zWPPGo9Rs9606	intact-crc:0B23E9559E95AEEE|rigid:jV1+Vp2agimTd/pJkM1NaVyxWWs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZC49	uniprotkb:Q9HC24	intact:EBI-2852010|uniprotkb:Q0WCB0	intact:EBI-1045545|uniprotkb:Q9UHY5|uniprotkb:Q9Y3C2|uniprotkb:Q542Z6|ensembl:ENSP00000350965.3	psi-mi:thii_yerpe(display_long)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:YPO3173(locus name)|uniprotkb:y1012(locus name)|uniprotkb:YP_0758(locus name)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym)	psi-mi:lfg4_human(display_long)|uniprotkb:Z-protein(gene name synonym)|uniprotkb:Protein S1R(gene name synonym)|uniprotkb:TMBIM4(gene name)|psi-mi:TMBIM4(display_short)|uniprotkb:CGI-119(orf name)|uniprotkb:GAAP(gene name synonym)|uniprotkb:Golgi anti-apoptotic protein(gene name synonym)|uniprotkb:LFG4(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852206|imex:IM-13779-5649	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR026340|interpro:IPR001763(Rhodanese-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|refseq:WP_002208658.1|go:""GO:0000049""(tRNA binding)|go:""GO:0002937""(tRNA 4-thiouridine biosynthesis)|go:""GO:0004810""(CCA tRNA nucleotidyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0009228""(thiamine biosynthetic process)|go:""GO:0009229""(thiamine diphosphate biosynthetic process)|go:""GO:0052837""(thiazole biosynthetic process)|go:""GO:0140741""(tRNA-uracil-4 sulfurtransferase activity)|interpro:IPR036873|interpro:IPR054173|refseq:YP_002348078.1|interpro:IPR049961|interpro:IPR049962|interpro:IPR050102|panther:PTHR43209(orthology-group)"	"refseq:NP_001269535.1|refseq:NP_001269538.1|refseq:NP_001269539.1|refseq:NP_057140.2|ensembl:ENSG00000155957.19(gene)|ensembl:ENST00000358230.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005795""(Golgi stack)|go:""GO:0006915""(apoptotic process)|go:""GO:0007626""(locomotory behavior)|go:""GO:0016020""(membrane)|go:""GO:0030968""(endoplasmic reticulum unfolded protein response)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0050848""(regulation of calcium-mediated signaling)|interpro:IPR006214(Protein of unknown function UPF0005)|panther:PTHR23291(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:JVdYYtaSxHT0xyr6zYDRPl2jCF4632	rogid:zkmPM2HoLpytHcy47b+gKBrEbN09606	intact-crc:0E8BF0598608222D|rigid:cHHF1eId+JLiRMJJgTzrhkJ1bsc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7CIP6	uniprotkb:O94876	intact:EBI-2852197|uniprotkb:Q74TN3	intact:EBI-2820525|uniprotkb:Q8IXM8|uniprotkb:Q68E06|uniprotkb:A8K5Y3|uniprotkb:B4DE04|ensembl:ENSP00000376930.3	psi-mi:q7cip6_yerpe(display_long)|uniprotkb:qacE(gene name)|psi-mi:qacE(display_short)|uniprotkb:YPO2333(locus name)	psi-mi:tmcc1_human(display_long)|uniprotkb:TMCC1(gene name)|psi-mi:TMCC1(display_short)|uniprotkb:KIAA0779(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852194|imex:IM-13779-5645	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR000390(Small multidrug resistance protein)|go:""GO:0005886""(plasma membrane)|go:""GO:0015199""(amino-acid betaine transmembrane transporter activity)|go:""GO:0015220""(choline transmembrane transporter activity)|go:""GO:0015297""(antiporter activity)|go:""GO:0015871""(choline transport)|go:""GO:0031460""(glycine betaine transport)|go:""GO:0055085""(transmembrane transport)|refseq:YP_002347300.1|interpro:IPR045324|panther:PTHR30561(orthology-group)"	"refseq:XP_011510874.1|refseq:XP_011510875.1|refseq:XP_011510878.1|refseq:XP_011510881.1|refseq:XP_011510884.1|refseq:NP_001017395.2|refseq:NP_001121696.1|refseq:XP_006713605.1|refseq:XP_006713606.1|refseq:XP_006713607.1|ensembl:ENSG00000172765.19(gene)|ensembl:ENST00000393238.8(transcript)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005791""(rough endoplasmic reticulum)|go:""GO:0005829""(cytosol)|go:""GO:0007029""(endoplasmic reticulum organization)|go:""GO:0012505""(endomembrane system)|go:""GO:0016197""(endosomal transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0090148""(membrane fission)|go:""GO:0097750""(endosome membrane tubulation)|go:""GO:0140284""(endoplasmic reticulum-endosome membrane contact site)|go:""GO:0140285""(endosome fission)|interpro:IPR019394|mint:O94876|refseq:XP_016861420.1|refseq:XP_016861421.1|refseq:XP_016861422.1|panther:PTHR17613(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:6Ga2PoftjeVUAYBkCvuFol1JigI632	rogid:gxHP7LGKWajp9+7rW6Llm1pNhTY9606	intact-crc:D0CE1EAC59828A3C|rigid:horJpbq25Qr3YlciSlkYZA6A/Bk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q969X1	uniprotkb:Q8D1J9	intact:EBI-2820569|uniprotkb:Q8TAM3|uniprotkb:Q8N1R3|uniprotkb:B3KQY6|uniprotkb:Q96K13|intact:EBI-28987734|ensembl:ENSP00000258412.3|ensembl:ENSP00000380025.2|ensembl:ENSP00000409738.1	intact:EBI-2844009|uniprotkb:Q74R75	psi-mi:lfg3_human(display_long)|uniprotkb:TMBIM1(gene name)|psi-mi:TMBIM1(display_short)|uniprotkb:RECS1(gene name synonym)|uniprotkb:Protein RECS1 homolog(gene name synonym)|uniprotkb:LFG3(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 1(gene name synonym)|uniprotkb:PP1201(orf name)|uniprotkb:PSEC0158(orf name)	psi-mi:q8d1j9_yerpe(display_long)|uniprotkb:uvrD(gene name)|psi-mi:uvrD(display_short)|uniprotkb:DNA 3'-5' helicase II(gene name synonym)|uniprotkb:YP_3206(locus name)|uniprotkb:y0389(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852213|imex:IM-13779-5647	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011509929.1|refseq:NP_071435.2|refseq:NP_001308356.1|refseq:NP_001308357.1|refseq:NP_001308358.1|refseq:NP_001308359.1|refseq:NP_001308361.1|refseq:NP_001308362.1|refseq:NP_001308364.1|refseq:NP_001308365.1|mint:Q969X1|ensembl:ENSG00000135926.15(gene)|ensembl:ENST00000258412.8(transcript)|ensembl:ENST00000396809.6(transcript)|ensembl:ENST00000444881.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005123""(death receptor binding)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1902045""(negative regulation of Fas signaling pathway)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:2000504""(positive regulation of blood vessel remodeling)|interpro:IPR006214(Protein of unknown function UPF0005)|reactome:R-HSA-6798695|panther:PTHR23291(orthology-group)"	"interpro:IPR005753(DNA helicase, ATP-dependent, UvrD type)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016787""(hydrolase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR013986(DNA helicase, DEXX box type)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BixfV0TRnui/iQXbrWx4ZrnFGsI9606	rogid:PolYsqnEbJnfKp6krRc+FLB+mdg632	intact-crc:25D7A82BD8C5DC44|rigid:erSECzoO+9s6ON+Vv2uATlW2nyg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q969X1	uniprotkb:Q8CWI4	intact:EBI-2820569|uniprotkb:Q8TAM3|uniprotkb:Q8N1R3|uniprotkb:B3KQY6|uniprotkb:Q96K13|intact:EBI-28987734|ensembl:ENSP00000258412.3|ensembl:ENSP00000380025.2|ensembl:ENSP00000409738.1	intact:EBI-2841215	psi-mi:lfg3_human(display_long)|uniprotkb:TMBIM1(gene name)|psi-mi:TMBIM1(display_short)|uniprotkb:RECS1(gene name synonym)|uniprotkb:Protein RECS1 homolog(gene name synonym)|uniprotkb:LFG3(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 1(gene name synonym)|uniprotkb:PP1201(orf name)|uniprotkb:PSEC0158(orf name)	psi-mi:q8cwi4_yerpe(display_long)|uniprotkb:kbl(gene name)|psi-mi:kbl(display_short)|uniprotkb:Glycine acetyltransferase(gene name synonym)|uniprotkb:y0081(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852220|imex:IM-13779-5648	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011509929.1|refseq:NP_071435.2|refseq:NP_001308356.1|refseq:NP_001308357.1|refseq:NP_001308358.1|refseq:NP_001308359.1|refseq:NP_001308361.1|refseq:NP_001308362.1|refseq:NP_001308364.1|refseq:NP_001308365.1|mint:Q969X1|ensembl:ENSG00000135926.15(gene)|ensembl:ENST00000258412.8(transcript)|ensembl:ENST00000396809.6(transcript)|ensembl:ENST00000444881.5(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0005123""(death receptor binding)|go:""GO:0005262""(calcium channel activity)|go:""GO:0005765""(lysosomal membrane)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005886""(plasma membrane)|go:""GO:0010008""(endosome membrane)|go:""GO:0016020""(membrane)|go:""GO:0035579""(specific granule membrane)|go:""GO:0043086""(negative regulation of catalytic activity)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0043524""(negative regulation of neuron apoptotic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:0097190""(apoptotic signaling pathway)|go:""GO:1902042""(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:""GO:1902045""(negative regulation of Fas signaling pathway)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:2000504""(positive regulation of blood vessel remodeling)|interpro:IPR006214(Protein of unknown function UPF0005)|reactome:R-HSA-6798695|panther:PTHR23291(orthology-group)"	"interpro:IPR011282(2-amino-3-ketobutyrate coenzyme A ligase)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0008890""(glycine C-acetyltransferase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0016874""(ligase activity)|go:""GO:0019518""(L-threonine catabolic process to glycine)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR050087"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:BixfV0TRnui/iQXbrWx4ZrnFGsI9606	rogid:uETD2R/0GvIqPvz6yt39/YuJzJQ632	intact-crc:BCE5DC7CDB0DD6E6|rigid:wAkCY/iOt58mNSLdfKh3zVwIf3w	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q15363	uniprotkb:Q8CZY0	intact:EBI-998485|ensembl:ENSP00000262225.3	intact:EBI-2843763	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:q8czy0_yerpe(display_long)|uniprotkb:y3182(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852187|imex:IM-13779-5644	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006806.1|refseq:NP_001308374.1|ensembl:ENSG00000086598.11(gene)|ensembl:ENST00000262225.8(transcript)|go:""GO:0000139""(Golgi membrane)|go:""GO:0001843""(neural tube closure)|go:""GO:0001893""(maternal placenta development)|go:""GO:0001947""(heart looping)|go:""GO:0005109""(frizzled binding)|go:""GO:0005119""(smoothened binding)|go:""GO:0005783""(endoplasmic reticulum)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005793""(endoplasmic reticulum-Golgi intermediate compartment)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0006954""(inflammatory response)|go:""GO:0007030""(Golgi organization)|go:""GO:0009306""(protein secretion)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0012507""(ER to Golgi transport vesicle membrane)|go:""GO:0016020""(membrane)|go:""GO:0030133""(transport vesicle)|go:""GO:0030134""(COPII-coated ER to Golgi transport vesicle)|go:""GO:0030137""(COPI-coated vesicle)|go:""GO:0030663""(COPI-coated vesicle membrane)|go:""GO:0032525""(somite rostral/caudal axis specification)|go:""GO:0032580""(Golgi cisterna membrane)|go:""GO:0033116""(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:""GO:0034260""(negative regulation of GTPase activity)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035459""(vesicle cargo loading)|go:""GO:0036342""(post-anal tail morphogenesis)|go:""GO:0036499""(PERK-mediated unfolded protein response)|go:""GO:0042589""(zymogen granule membrane)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0045879""(negative regulation of smoothened signaling pathway)|go:""GO:0048205""(COPI coating of Golgi vesicle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0060670""(branching involved in labyrinthine layer morphogenesis)|go:""GO:0060716""(labyrinthine layer blood vessel development)|go:""GO:0060717""(chorion development)|go:""GO:0072595""(maintenance of protein localization in organelle)|go:""GO:0072659""(protein localization to plasma membrane)|go:""GO:0090158""(endoplasmic reticulum membrane organization)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:1905069""(allantois development)|go:""GO:2000638""(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q15363|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|panther:PTHR22811(orthology-group)"	"interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006656(Molybdopterin oxidoreductase)|go:""GO:0016491""(oxidoreductase activity)|go:""GO:0043546""(molybdopterin cofactor binding)|go:""GO:0046872""(metal ion binding)|interpro:IPR041954|interpro:IPR050612"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	rogid:Y5d3heMPjpe23bUutQ9OKW+v73g632	intact-crc:860169891D72C1D5|rigid:L+0Cz7ofCFor1Nqnbt/yJlkq7K4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99805	uniprotkb:Q7ARD3	intact:EBI-2852254|uniprotkb:Q2TAY5|uniprotkb:A8K399|ensembl:ENSP00000365567.3|ensembl:ENSP00000493515.1	intact:EBI-2840408|uniprotkb:O68760|uniprotkb:Q74YL2	psi-mi:tm9s2_human(display_long)|uniprotkb:TM9SF2(gene name)|psi-mi:TM9SF2(display_short)|uniprotkb:p76(gene name synonym)	psi-mi:q7ard3_yerpe(display_long)|uniprotkb:YPMT1.45c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852275|imex:IM-13779-5651	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004791.1|ensembl:ENSG00000125304.10(gene)|ensembl:ENST00000376387.5(transcript)|ensembl:ENST00000642475.1(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005886""(plasma membrane)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0006688""(glycosphingolipid biosynthetic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0010908""(regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|interpro:IPR004240(""Nonaspanin (TM9SF)"")|mint:Q99805|panther:PTHR10766(orthology-group)"	refseq:NP_395386.1	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qg5QSnzX8+4H0Nfab7Ci9n9igc09606	rogid:Oyvqs01O/Z0MHqhT47eLhF6dZBQ632	intact-crc:4C2C9C5775B20ADA|rigid:+KwTJhM3XwQ3ClBkY9E6LgebTvw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q99805	uniprotkb:A0A5P8YB02	intact:EBI-2852254|uniprotkb:Q2TAY5|uniprotkb:A8K399|ensembl:ENSP00000365567.3|ensembl:ENSP00000493515.1	intact:EBI-2852267|uniprotkb:Q74QW9|uniprotkb:A0A0H2W7I3|uniprotkb:Q7CG03|uniprotkb:A0A384L523	psi-mi:tm9s2_human(display_long)|uniprotkb:TM9SF2(gene name)|psi-mi:TM9SF2(display_short)|uniprotkb:p76(gene name synonym)	psi-mi:a0a5p8yb02_yerpe(display_long)|uniprotkb:YPO3973(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852264|imex:IM-13779-5652	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_004791.1|ensembl:ENSG00000125304.10(gene)|ensembl:ENST00000376387.5(transcript)|ensembl:ENST00000642475.1(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005886""(plasma membrane)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0006688""(glycosphingolipid biosynthetic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0010908""(regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|interpro:IPR004240(""Nonaspanin (TM9SF)"")|mint:Q99805|panther:PTHR10766(orthology-group)"	"interpro:IPR024079|interpro:IPR016294(Peptidase M10B)|interpro:IPR013858(Peptidase M10,  serralysin, C-terminal)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|interpro:IPR019960|go:""GO:0004222""(metalloendopeptidase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005615""(extracellular space)|go:""GO:0006508""(proteolysis)|go:""GO:0008270""(zinc ion binding)|go:""GO:0031012""(extracellular matrix)|interpro:IPR034033|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|refseq:YP_002348843.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:qg5QSnzX8+4H0Nfab7Ci9n9igc09606	rogid:flDgYZ62TnAy5NPdVdn4WU9GM3Q632	intact-crc:62AD3E50EB4E1C05|rigid:ajOc8vtrLyquqmNM7p4K3xgjNh4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9HD45	uniprotkb:Q7CL81	intact:EBI-2814047|uniprotkb:Q9NWL8|uniprotkb:Q5TB57|uniprotkb:Q9UHW8|uniprotkb:Q6UWE7|uniprotkb:Q9P0G9|ensembl:ENSP00000360184.4	intact:EBI-2852239|uniprotkb:Q74PP8	psi-mi:tm9s3_human(display_long)|uniprotkb:TM9SF3(gene name)|psi-mi:TM9SF3(display_short)|uniprotkb:SMBP(gene name synonym)|uniprotkb:EP70-P-iso(gene name synonym)|uniprotkb:SM-11044-binding protein(gene name synonym)|uniprotkb:UNQ245/PRO282(orf name)	psi-mi:q7cl81_yerpe(display_long)|uniprotkb:treB(gene name)|psi-mi:treB(display_short)|uniprotkb:YPO3697(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852244|imex:IM-13779-5650	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_064508.3|ensembl:ENSG00000077147.16(gene)|ensembl:ENST00000371142.9(transcript)|go:""GO:0016020""(membrane)|go:""GO:0072657""(protein localization to membrane)|interpro:IPR004240(""Nonaspanin (TM9SF)"")|mint:Q9HD45|panther:PTHR10766(orthology-group)"	"interpro:IPR018113|interpro:IPR001996(Phosphotransferase system, EIIB)|interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR013013(Phosphotransferase system, EIIC component, type 1)|interpro:IPR011296(Phosphotransferase system, trehalose-specific IIBC component)|go:""GO:0005886""(plasma membrane)|go:""GO:0008982""(""protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"")|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:""GO:0015574""(trehalose transmembrane transporter activity)|go:""GO:0015771""(trehalose transport)|go:""GO:0016301""(kinase activity)|go:""GO:0090589""(protein-phosphocysteine-trehalose phosphotransferase system transporter activity)|interpro:IPR036878|interpro:IPR050558|panther:PTHR30175(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:/9Z/a+36wE2FTbIyQ/zWPPGo9Rs9606	rogid:MIkTe/Rb+6LtHGd0IvWHhqfr8ao632	intact-crc:AAAFF2559F5FAFFB|rigid:GAAlvGwW3eSMAgDIq30OPsrVNZM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D0D4	uniprotkb:Q99805	intact:EBI-2847212	intact:EBI-2852254|uniprotkb:Q2TAY5|uniprotkb:A8K399|ensembl:ENSP00000365567.3|ensembl:ENSP00000493515.1	psi-mi:q8d0d4_yerpe(display_long)|uniprotkb:hmsH(gene name)|psi-mi:hmsH(display_short)|uniprotkb:y2359(locus name)	psi-mi:tm9s2_human(display_long)|uniprotkb:TM9SF2(gene name)|psi-mi:TM9SF2(display_short)|uniprotkb:p76(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852251|imex:IM-13779-5653	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR023870|interpro:IPR011990(Tetratricopeptide-like helical)|go:""GO:1901515""(poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity)|interpro:IPR049003"	"refseq:NP_004791.1|ensembl:ENSG00000125304.10(gene)|ensembl:ENST00000376387.5(transcript)|ensembl:ENST00000642475.1(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005815""(microtubule organizing center)|go:""GO:0005886""(plasma membrane)|go:""GO:0006672""(ceramide metabolic process)|go:""GO:0006688""(glycosphingolipid biosynthetic process)|go:""GO:0010008""(endosome membrane)|go:""GO:0010908""(regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016020""(membrane)|go:""GO:0070062""(extracellular exosome)|go:""GO:0072657""(protein localization to membrane)|interpro:IPR004240(""Nonaspanin (TM9SF)"")|mint:Q99805|panther:PTHR10766(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oBs/IRM9/gKecuXNw9IoCZLu4Vw632	rogid:qg5QSnzX8+4H0Nfab7Ci9n9igc09606	intact-crc:30C9221BAB24E133|rigid:Xmx/OmzgNCCDDvpn0rdO0vw3NT0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D020	uniprotkb:P29401	intact:EBI-2841685|uniprotkb:Q74WI5	intact:EBI-1050560|uniprotkb:Q8TBA3|uniprotkb:Q96HH3|uniprotkb:A8K089|uniprotkb:B4DE31|uniprotkb:E7EPA7|intact:EBI-11110174|ensembl:ENSP00000405455.2|ensembl:ENSP00000417773.1	psi-mi:q8d020_yerpe(display_long)|uniprotkb:bglA(gene name)|psi-mi:bglA(display_short)|uniprotkb:y2932(locus name)	psi-mi:tkt_human(display_long)|uniprotkb:TKT(gene name)|psi-mi:TKT(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852320|imex:IM-13779-5656	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR018120|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR033132|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005975""(carbohydrate metabolic process)"	"ensembl:ENSG00000163931.17(gene)|ensembl:ENST00000423525.6(transcript)|ensembl:ENST00000462138.6(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004802""(transketolase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0009052""(pentose-phosphate shunt, non-oxidative branch)|go:""GO:0016604""(nuclear body)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0031982""(vesicle)|go:""GO:0040008""(regulation of growth)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046166""(glyceraldehyde-3-phosphate biosynthetic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1901159""(xylulose 5-phosphate biosynthetic process)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|interpro:IPR049557|interpro:IPR051424|mint:P29401|rcsb pdb:3MOS|rcsb pdb:3OOY|rcsb pdb:4KXU|rcsb pdb:4KXV|rcsb pdb:4KXW|rcsb pdb:4KXX|rcsb pdb:4KXY|rcsb pdb:6HA3|rcsb pdb:6HAD|rcsb pdb:6RJB|rcsb pdb:8WA8|rcsb pdb:8WA9|rcsb pdb:8WAA|reactome:R-HSA-163754|reactome:R-HSA-71336|reactome:R-HSA-9818028|refseq:NP_001055.1|refseq:NP_001128527.1|refseq:NP_001244957.1|refseq:XP_011532356.1|efo:""Orphanet:488618""|panther:PTHR43195(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:FIpi7GKMp+RoIo3dUToc4hru/9o632	rogid:Z3Ad5GdEd0rFCT9uHv85N+2KAAY9606	intact-crc:9E07153A730A5325|rigid:tkPh12CIAlEsYWUpPvQKMNY0yF0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YBG5	uniprotkb:P31314	intact:EBI-2840276|uniprotkb:Q74R47|uniprotkb:Q0WAJ9|uniprotkb:A0A384KR68|uniprotkb:Q7CKW7|uniprotkb:A0A2U2GXT2	intact:EBI-2820655|uniprotkb:Q9HCA0|uniprotkb:O75699|uniprotkb:Q9UD59|uniprotkb:Q5VXP2|uniprotkb:A1L4G3|ensembl:ENSP00000359215.6	psi-mi:a0a5p8ybg5_yerpe(display_long)|uniprotkb:ftsS(gene name)|psi-mi:ftsS(display_short)|uniprotkb:ftsX(gene name synonym)|uniprotkb:YPO3812(locus name)	psi-mi:tlx1_human(display_long)|uniprotkb:TLX1(gene name)|psi-mi:TLX1(display_short)|uniprotkb:HOX11(gene name synonym)|uniprotkb:TCL3(gene name synonym)|uniprotkb:Homeobox protein Hox-11(gene name synonym)|uniprotkb:Proto-oncogene TCL-3(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 3(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852282|imex:IM-13779-5654	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004513(ABC transporter, FtsX cell division permease)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|go:""GO:0005886""(plasma membrane)|go:""GO:0051301""(cell division)|interpro:IPR040690|refseq:WP_002211505.1|refseq:YP_002348689.1|interpro:IPR047590"	"ensembl:ENSG00000107807.13(gene)|ensembl:ENST00000370196.11(transcript)|go:""GO:0000785""(chromatin)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001228""(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:""GO:0005634""(nucleus)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0048513""(animal organ development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_001182446.1|refseq:NP_005512.1|dip:DIP-155N|efo:""Orphanet:99861""|panther:PTHR45921(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:SDuJtWCYjJZjPF8p6X74WTEddjI632	rogid:9T87oIC0qC7OWt1ZIdxZhNfA6KA9606	intact-crc:97647F5520AAA9A9|rigid:ad/VR62CyHAdcJoCW/eft2v+p/M	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D035	uniprotkb:P29401	intact:EBI-2852311|uniprotkb:Q74VP5	intact:EBI-1050560|uniprotkb:Q8TBA3|uniprotkb:Q96HH3|uniprotkb:A8K089|uniprotkb:B4DE31|uniprotkb:E7EPA7|intact:EBI-11110174|ensembl:ENSP00000405455.2|ensembl:ENSP00000417773.1	psi-mi:nasll_yerpe(display_long)|uniprotkb:Nicotianamine synthase-like enzyme(gene name synonym)|uniprotkb:NCTC144_04063(orf name)|uniprotkb:YP_1250(locus name)|uniprotkb:y2836(locus name)|uniprotkb:smtA3(gene name)|psi-mi:smtA3(display_short)	psi-mi:tkt_human(display_long)|uniprotkb:TKT(gene name)|psi-mi:TKT(display_short)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852308|imex:IM-13779-5657	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002211374.1|interpro:IPR004298(Nicotianamine synthase)|go:""GO:0030410""(nicotianamine synthase activity)|go:""GO:0030418""(nicotianamine biosynthetic process)|interpro:IPR036291|interpro:IPR029063"	"ensembl:ENSG00000163931.17(gene)|ensembl:ENST00000423525.6(transcript)|ensembl:ENST00000462138.6(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004802""(transketolase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0009052""(pentose-phosphate shunt, non-oxidative branch)|go:""GO:0016604""(nuclear body)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0031982""(vesicle)|go:""GO:0040008""(regulation of growth)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046166""(glyceraldehyde-3-phosphate biosynthetic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1901159""(xylulose 5-phosphate biosynthetic process)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|interpro:IPR049557|interpro:IPR051424|mint:P29401|rcsb pdb:3MOS|rcsb pdb:3OOY|rcsb pdb:4KXU|rcsb pdb:4KXV|rcsb pdb:4KXW|rcsb pdb:4KXX|rcsb pdb:4KXY|rcsb pdb:6HA3|rcsb pdb:6HAD|rcsb pdb:6RJB|rcsb pdb:8WA8|rcsb pdb:8WA9|rcsb pdb:8WAA|reactome:R-HSA-163754|reactome:R-HSA-71336|reactome:R-HSA-9818028|refseq:NP_001055.1|refseq:NP_001128527.1|refseq:NP_001244957.1|refseq:XP_011532356.1|efo:""Orphanet:488618""|panther:PTHR43195(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Xf1YcdJ7ZyNjET3g2uMcryoJWzg632	rogid:Z3Ad5GdEd0rFCT9uHv85N+2KAAY9606	intact-crc:2676153A72250D46|rigid:QDSwsAk4crfUUXsYDQB8/g3pBps	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YFJ9	uniprotkb:Q9UKI8	intact:EBI-2852296|uniprotkb:Q74U44|uniprotkb:Q7CIC4|uniprotkb:Q0WF92	intact:EBI-740492|intact:EBI-28969610|uniprotkb:Q14150|uniprotkb:Q8N591|uniprotkb:Q9NYH2|uniprotkb:Q9Y4F6|uniprotkb:B3KR15|uniprotkb:B4DX87|ensembl:ENSP00000411099.2	psi-mi:a0a5p8yfj9_yerpe(display_long)|uniprotkb:pykA(gene name)|psi-mi:pykA(display_short)|uniprotkb:YPO2064(locus name)	psi-mi:tlk1_human(display_long)|uniprotkb:Tousled-like kinase 1(gene name synonym)|uniprotkb:PKU-beta(gene name synonym)|uniprotkb:TLK1(gene name)|psi-mi:TLK1(display_short)|uniprotkb:KIAA0137(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852301|imex:IM-13779-5658	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018209|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|refseq:WP_002211193.1|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004743""(pyruvate kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006096""(glycolytic process)|go:""GO:0016301""(kinase activity)|go:""GO:0030955""(potassium ion binding)|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918|refseq:YP_002347046.1|panther:PTHR11817(orthology-group)"	"refseq:NP_036422.3|refseq:NP_001130026.1|refseq:NP_001130027.1|ensembl:ENSG00000198586.14(gene)|ensembl:ENST00000431350.7(transcript)|go:""GO:0004674""(protein serine/threonine kinase activity)|go:""GO:0004676""(3-phosphoinositide-dependent protein kinase activity)|go:""GO:0004677""(DNA-dependent protein kinase activity)|go:""GO:0004679""(AMP-activated protein kinase activity)|go:""GO:0004694""(eukaryotic translation initiation factor 2alpha kinase activity)|go:""GO:0004711""(ribosomal protein S6 kinase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006468""(protein phosphorylation)|go:""GO:0006886""(intracellular protein transport)|go:""GO:0006974""(DNA damage response)|go:""GO:0007059""(chromosome segregation)|go:""GO:0035175""(histone H3S10 kinase activity)|go:""GO:0035402""(histone H3T11 kinase activity)|go:""GO:0035403""(histone H3T6 kinase activity)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0035979""(histone H2AXS139 kinase activity)|go:""GO:0044022""(histone H3S28 kinase activity)|go:""GO:0044023""(histone H4S1 kinase activity)|go:""GO:0044024""(histone H2AS1 kinase activity)|go:""GO:0044025""(histone H2BS14 kinase activity)|go:""GO:0072354""(histone H3T3 kinase activity)|go:""GO:0072371""(histone H2AS121 kinase activity)|go:""GO:0072518""(Rho-dependent protein serine/threonine kinase activity)|go:""GO:0106310""(protein serine kinase activity)|go:""GO:0140823""(histone H2BS36 kinase activity)|go:""GO:0140855""(histone H3S57 kinase activity)|go:""GO:0140857""(histone H3T45 kinase activity)|go:""GO:1902275""(regulation of chromatin organization)|go:""GO:1990244""(histone H2AT120 kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9UKI8|refseq:XP_016860910.1|refseq:XP_016860911.1|panther:PTHR22974(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:lG4rZnQJ0jht/LKG/nwKgIZJvC8632	rogid:XEv3blkyAPiq97nCSgBZLs6FiZA9606	intact-crc:A28833A00C05AC7D|rigid:1Lt+Q7+aAqj/4FMMl/uZGmGIJ3A	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O00206	uniprotkb:Q8ZJ10	intact:EBI-528701|uniprotkb:Q9UK78|uniprotkb:Q9UM57|uniprotkb:A8K1Y8|uniprotkb:A9XLP9|uniprotkb:A9XLQ0|uniprotkb:A9XLQ1|uniprotkb:B4E194|uniprotkb:Q5VZI8|uniprotkb:Q5VZI9|uniprotkb:D1CS53|uniprotkb:D1CS52|ensembl:ENSP00000363089.5	intact:EBI-2845732|uniprotkb:Q0WJY7	psi-mi:tlr4_human(display_long)|uniprotkb:TLR4(gene name)|psi-mi:TLR4(display_short)|uniprotkb:hToll(gene name synonym)	psi-mi:alr_yerpe(display_long)|uniprotkb:alr(gene name)|psi-mi:alr(display_short)|uniprotkb:YPO0321(locus name)|uniprotkb:YP_0476(locus name)|uniprotkb:y0578(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852289|imex:IM-13779-5655	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:117""|ensembl:ENSG00000136869.16(gene)|ensembl:ENST00000355622.8(transcript)|go:""GO:0001530""(lipopolysaccharide binding)|go:""GO:0001540""(amyloid-beta binding)|go:""GO:0001726""(ruffle)|go:""GO:0001875""(lipopolysaccharide immune receptor activity)|go:""GO:0001891""(phagocytic cup)|go:""GO:0002224""(toll-like receptor signaling pathway)|go:""GO:0002246""(wound healing involved in inflammatory response)|go:""GO:0002322""(B cell proliferation involved in immune response)|go:""GO:0002537""(nitric oxide production involved in inflammatory response)|go:""GO:0002730""(regulation of dendritic cell cytokine production)|go:""GO:0002755""(MyD88-dependent toll-like receptor signaling pathway)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005102""(signaling receptor binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0005769""(early endosome)|go:""GO:0005886""(plasma membrane)|go:""GO:0006809""(nitric oxide biosynthetic process)|go:""GO:0006909""(phagocytosis)|go:""GO:0006954""(inflammatory response)|go:""GO:0006955""(immune response)|go:""GO:0007252""(I-kappaB phosphorylation)|go:""GO:0007254""(JNK cascade)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010008""(endosome membrane)|go:""GO:0010467""(gene expression)|go:""GO:0010572""(positive regulation of platelet activation)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0014002""(astrocyte development)|go:""GO:0014004""(microglia differentiation)|go:""GO:0014911""(positive regulation of smooth muscle cell migration)|go:""GO:0016046""(detection of fungus)|go:""GO:0030890""(positive regulation of B cell proliferation)|go:""GO:0031663""(lipopolysaccharide-mediated signaling pathway)|go:""GO:0032496""(response to lipopolysaccharide)|go:""GO:0032497""(detection of lipopolysaccharide)|go:""GO:0032689""(negative regulation of type II interferon production)|go:""GO:0032700""(negative regulation of interleukin-17 production)|go:""GO:0032707""(negative regulation of interleukin-23 production)|go:""GO:0032715""(negative regulation of interleukin-6 production)|go:""GO:0032720""(negative regulation of tumor necrosis factor production)|go:""GO:0032722""(positive regulation of chemokine production)|go:""GO:0032727""(positive regulation of interferon-alpha production)|go:""GO:0032728""(positive regulation of interferon-beta production)|go:""GO:0032729""(positive regulation of type II interferon production)|go:""GO:0032731""(positive regulation of interleukin-1 beta production)|go:""GO:0032732""(positive regulation of interleukin-1 production)|go:""GO:0032733""(positive regulation of interleukin-10 production)|go:""GO:0032735""(positive regulation of interleukin-12 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032757""(positive regulation of interleukin-8 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032874""(positive regulation of stress-activated MAPK cascade)|go:""GO:0034142""(toll-like receptor 4 signaling pathway)|go:""GO:0035666""(TRIF-dependent toll-like receptor signaling pathway)|go:""GO:0036120""(cellular response to platelet-derived growth factor stimulus)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0042088""(T-helper 1 type immune response)|go:""GO:0042116""(macrophage activation)|go:""GO:0042742""(defense response to bacterium)|go:""GO:0042802""(identical protein binding)|go:""GO:0043032""(positive regulation of macrophage activation)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0043406""(positive regulation of MAP kinase activity)|go:""GO:0045087""(innate immune response)|go:""GO:0045342""(MHC class II biosynthetic process)|go:""GO:0045348""(positive regulation of MHC class II biosynthetic process)|go:""GO:0045429""(positive regulation of nitric oxide biosynthetic process)|go:""GO:0045671""(negative regulation of osteoclast differentiation)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046330""(positive regulation of JNK cascade)|go:""GO:0046696""(lipopolysaccharide receptor complex)|go:""GO:0046982""(protein heterodimerization activity)|go:""GO:0048471""(perinuclear region of cytoplasm)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050829""(defense response to Gram-negative bacterium)|go:""GO:0051092""(positive regulation of NF-kappaB transcription factor activity)|go:""GO:0051403""(stress-activated MAPK cascade)|go:""GO:0051770""(obsolete positive regulation of nitric-oxide synthase biosynthetic process)|go:""GO:0060729""(intestinal epithelial structure maintenance)|go:""GO:0060907""(positive regulation of macrophage cytokine production)|go:""GO:0061809""(NAD+ nucleosidase activity, cyclic ADP-ribose generating)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0070373""(negative regulation of ERK1 and ERK2 cascade)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070427""(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:""GO:0070430""(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:""GO:0070431""(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0070434""(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:""GO:0071222""(cellular response to lipopolysaccharide)|go:""GO:0071223""(cellular response to lipoteichoic acid)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071346""(cellular response to type II interferon)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|go:""GO:0140052""(cellular response to oxidised low-density lipoprotein particle stimulus)|go:""GO:1900017""(positive regulation of cytokine production involved in inflammatory response)|go:""GO:1900227""(positive regulation of NLRP3 inflammasome complex assembly)|go:""GO:1901224""(positive regulation of non-canonical NF-kappaB signal transduction)|go:""GO:1903428""(positive regulation of reactive oxygen species biosynthetic process)|go:""GO:1903974""(positive regulation of cellular response to macrophage colony-stimulating factor stimulus)|go:""GO:1904466""(positive regulation of matrix metallopeptidase secretion)|go:""GO:1904646""(cellular response to amyloid-beta)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2001238""(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR025875|interpro:IPR032675|interpro:IPR035897|mint:O00206|rcsb pdb:2Z62|rcsb pdb:2Z63|rcsb pdb:2Z65|rcsb pdb:2Z66|rcsb pdb:3FXI|rcsb pdb:3UL7|rcsb pdb:3UL8|rcsb pdb:3UL9|rcsb pdb:3ULA|rcsb pdb:4G8A|rcsb pdb:5NAM|rcsb pdb:5NAO|rcsb pdb:8WO1|rcsb pdb:8WTA|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-9707616|reactome:R-HSA-975163|reactome:R-HSA-9820960|reactome:R-HSA-9824878|reactome:R-HSA-9833110|refseq:NP_003257.1|refseq:NP_612564.1|refseq:NP_612567.1|dip:DIP-34769N|panther:PTHR24365(orthology-group)"	"interpro:IPR000821(Alanine racemase region)|interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR011079(Alanine racemase, C-terminal)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR020622|interpro:IPR029066|refseq:WP_002209096.1|go:""GO:0005829""(cytosol)|go:""GO:0008784""(alanine racemase activity)|go:""GO:0030170""(pyridoxal phosphate binding)|go:""GO:0030632""(D-alanine biosynthetic process)|refseq:YP_002345401.1|panther:PTHR30511(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:4flqeyn60Q/64s8vQQHzlYDWz6w9606	rogid:DHbxD7IyYyhVi917Zw+/1ybH+hI632	intact-crc:00ECF5B0B825E169|rigid:ybQggQ8y73TOlOMAS0k/d0hsoes	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:O95478	uniprotkb:A0A380PJJ5	intact:EBI-2852366|ensembl:ENSP00000483484.1	intact:EBI-2845694|uniprotkb:Q0WI50|uniprotkb:Q7CGN7	psi-mi:nsa2_human(display_long)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:TINP1(gene name synonym)|uniprotkb:Hairy cell leukemia protein 1(gene name synonym)|uniprotkb:TGF-beta-inducible nuclear protein 1(gene name synonym)|uniprotkb:HUSSY-29(orf name)	psi-mi:a0a380pjj5_yerpe(display_long)|uniprotkb:iucD(gene name)|psi-mi:iucD(display_short)|uniprotkb:YPO0993(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852370|imex:IM-13779-5661	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_055701.1|refseq:NP_001258594.1|ensembl:ENSG00000164346.10(gene)|ensembl:ENST00000610426.5(transcript)|go:""GO:0000460""(maturation of 5.8S rRNA)|go:""GO:0000470""(maturation of LSU-rRNA)|go:""GO:0003723""(RNA binding)|go:""GO:0005730""(nucleolus)|go:""GO:0030687""(preribosome, large subunit precursor)|interpro:IPR022309|interpro:IPR039411|mint:O95478|rcsb pdb:8FKR|rcsb pdb:8FKS|rcsb pdb:8FKT|rcsb pdb:8FKU|rcsb pdb:8FKV|rcsb pdb:8FKW|rcsb pdb:8FKX|rcsb pdb:8FKY|rcsb pdb:8FKZ|rcsb pdb:8FL0|rcsb pdb:8FL2|rcsb pdb:8FL3|rcsb pdb:8FL4|rcsb pdb:8FL6|rcsb pdb:8FL7|rcsb pdb:8FL9|rcsb pdb:8IDY|rcsb pdb:8IE3|rcsb pdb:8INE|rcsb pdb:8INF|rcsb pdb:8INK|rcsb pdb:8IPD|rcsb pdb:8IPX|rcsb pdb:8IPY|rcsb pdb:8IR1|rcsb pdb:8IR3|panther:PTHR12642(orthology-group)"	"interpro:IPR025700|refseq:WP_002211647.1|go:""GO:0047091""(""L-lysine 6-monooxygenase (NADPH) activity"")|interpro:IPR036188|refseq:YP_002346038.1|panther:PTHR42802(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:UHmCVn1q0LfipKMzSFQUzmVULD49606	rogid:Yq7E3I4Gh8JvT7cRCoaBFJsJ5fU632	intact-crc:E35F0C360A52CD8F|rigid:KSwL+ViTRYMnZIdRxRLsaArX1fs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4AZ94	uniprotkb:Q5JTD0	intact:EBI-2851965|uniprotkb:Q74Q42|uniprotkb:Q0WJF5|uniprotkb:Q7CG98|uniprotkb:A0A384LQH9	intact:EBI-2814077|uniprotkb:Q5JTD1|uniprotkb:Q68DB2|uniprotkb:Q5JWW1|uniprotkb:Q6P2P3|uniprotkb:Q9H7V7|uniprotkb:Q05BH9|ensembl:ENSP00000361522.5|ensembl:ENSP00000361527.1|ensembl:ENSP00000408769.2|intact:EBI-28984091	psi-mi:a0a3n4az94_yerpe(display_long)|uniprotkb:YPO0510(locus name)	psi-mi:tjap1_human(display_long)|uniprotkb:TJAP1(gene name)|psi-mi:TJAP1(display_short)|uniprotkb:PILT(gene name synonym)|uniprotkb:TJP4(gene name synonym)|uniprotkb:Protein incorporated later into tight junctions(gene name synonym)|uniprotkb:Tight junction protein 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852341|imex:IM-13779-5664	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR001646(Pentapeptide repeat)|refseq:WP_002214739.1|refseq:YP_002345583.1|interpro:IPR052949|panther:PTHR42999(orthology-group)	"refseq:XP_011513297.1|refseq:NP_001139492.1|refseq:NP_542171.2|refseq:NP_001139488.1|refseq:NP_001139489.1|refseq:NP_001139490.1|refseq:NP_001139491.1|refseq:XP_006715322.1|refseq:XP_006715323.1|refseq:XP_006715324.1|refseq:XP_006715325.1|refseq:XP_006715326.1|refseq:XP_006715328.1|refseq:XP_006715329.1|refseq:XP_006715312.1|refseq:XP_006715313.1|refseq:XP_006715314.1|refseq:XP_006715315.1|refseq:XP_006715317.1|refseq:XP_006715319.1|refseq:XP_006715320.1|ensembl:ENSG00000137221.14(gene)|ensembl:ENST00000372445.9(transcript)|ensembl:ENST00000372449.6(transcript)|ensembl:ENST00000438588.6(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007030""(Golgi organization)|interpro:IPR043441|interpro:IPR043470|mint:Q5JTD0|refseq:XP_016866977.1|refseq:XP_016866978.1|refseq:XP_016866981.1|refseq:XP_016866982.1|refseq:XP_016866979.1|refseq:XP_016866980.1|panther:PTHR28664(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:IAdCH4OmuZuWw6SQpr1rpqPzUIg632	rogid:Rn4TPVz2INwUzgJ7MGJ9CKHYaaM9606	intact-crc:11482C6AE3A0790B|rigid:mMGpZjrJCyYlvNUghsZ1WXD0kI8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P29401	uniprotkb:Q8CK83	intact:EBI-1050560|uniprotkb:Q8TBA3|uniprotkb:Q96HH3|uniprotkb:A8K089|uniprotkb:B4DE31|uniprotkb:E7EPA7|intact:EBI-11110174|ensembl:ENSP00000405455.2|ensembl:ENSP00000417773.1	intact:EBI-2851851|uniprotkb:Q74QS6	psi-mi:tkt_human(display_long)|uniprotkb:TKT(gene name)|psi-mi:TKT(display_short)	psi-mi:q8ck83_yerpe(display_long)|uniprotkb:accC1(gene name)|psi-mi:accC1(display_short)|uniprotkb:YP_3384(locus name)|uniprotkb:y4042(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852327|imex:IM-13779-5659	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000163931.17(gene)|ensembl:ENST00000423525.6(transcript)|ensembl:ENST00000462138.6(transcript)|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004802""(transketolase activity)|go:""GO:0005509""(calcium ion binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005777""(peroxisome)|go:""GO:0005789""(endoplasmic reticulum membrane)|go:""GO:0005829""(cytosol)|go:""GO:0006098""(pentose-phosphate shunt)|go:""GO:0009052""(pentose-phosphate shunt, non-oxidative branch)|go:""GO:0016604""(nuclear body)|go:""GO:0030976""(thiamine pyrophosphate binding)|go:""GO:0031982""(vesicle)|go:""GO:0040008""(regulation of growth)|go:""GO:0042803""(protein homodimerization activity)|go:""GO:0046166""(glyceraldehyde-3-phosphate biosynthetic process)|go:""GO:0070062""(extracellular exosome)|go:""GO:1901159""(xylulose 5-phosphate biosynthetic process)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|interpro:IPR049557|interpro:IPR051424|mint:P29401|rcsb pdb:3MOS|rcsb pdb:3OOY|rcsb pdb:4KXU|rcsb pdb:4KXV|rcsb pdb:4KXW|rcsb pdb:4KXX|rcsb pdb:4KXY|rcsb pdb:6HA3|rcsb pdb:6HAD|rcsb pdb:6RJB|rcsb pdb:8WA8|rcsb pdb:8WA9|rcsb pdb:8WAA|reactome:R-HSA-163754|reactome:R-HSA-71336|reactome:R-HSA-9818028|refseq:NP_001055.1|refseq:NP_001128527.1|refseq:NP_001244957.1|refseq:XP_011532356.1|efo:""Orphanet:488618""|panther:PTHR43195(orthology-group)"	"interpro:IPR011761(ATP-grasp fold)|go:""GO:0005524""(ATP binding)|go:""GO:0016874""(ligase activity)|go:""GO:0046872""(metal ion binding)|interpro:IPR052032"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Z3Ad5GdEd0rFCT9uHv85N+2KAAY9606	rogid:zWNetqBcgNgoffpGm1WuBpGKZiA632	intact-crc:17584C6D73ED1C58|rigid:AEaD5T9O2oOuhPdy38s5ev/ZQFA	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9BVW5	uniprotkb:A0A5P8YB58	intact:EBI-2515360|uniprotkb:Q9NWZ6|uniprotkb:B2CW64|ensembl:ENSP00000261881.4	intact:EBI-2852358|uniprotkb:Q74R98|uniprotkb:Q0WAD8|uniprotkb:A0A0H2W770|uniprotkb:Q7CKZ4|uniprotkb:A0A384KFQ4	psi-mi:tipin_human(display_long)|uniprotkb:TIPIN(gene name)|psi-mi:TIPIN(display_short)	psi-mi:a0a5p8yb58_yerpe(display_long)|uniprotkb:YPO3874(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852355|imex:IM-13779-5663	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011520045.1|refseq:NP_060328.2|ensembl:ENSG00000075131.10(gene)|ensembl:ENST00000261881.9(transcript)|go:""GO:0000076""(DNA replication checkpoint signaling)|go:""GO:0000785""(chromatin)|go:""GO:0003677""(DNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0009411""(response to UV)|go:""GO:0031297""(replication fork processing)|go:""GO:0031298""(replication fork protection complex)|go:""GO:0031573""(mitotic intra-S DNA damage checkpoint signaling)|go:""GO:0033262""(regulation of nuclear cell cycle DNA replication)|go:""GO:0043111""(replication fork arrest)|go:""GO:0044770""(cell cycle phase transition)|go:""GO:0051301""(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|mint:Q9BVW5|rcsb pdb:7PFO|rcsb pdb:7PLO|rcsb pdb:8B9D|reactome:R-HSA-5693607|refseq:XP_005254578.1|refseq:XP_005254579.1|refseq:NP_001276915.1|refseq:XP_006720657.1|refseq:XP_016877879.1|dip:DIP-53658N|panther:PTHR13220(orthology-group)"	"interpro:IPR007788(Glutamine cyclotransferase)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|refseq:WP_002211996.1|go:""GO:0016603""(glutaminyl-peptide cyclotransferase activity)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:YP_002348750.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:vNvUsnDmodQH/QQqJBYYSbjIdKo9606	rogid:VlD8/i6j+aaENTtf9uu/PAmwmH8632	intact-crc:730F9BA1C832A957|rigid:qpq26tspK/gWWCZNDjdSdw6xFmY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q07352	uniprotkb:A0A380PL37	intact:EBI-721823|uniprotkb:Q13851|ensembl:ENSP00000337386.3|ensembl:ENSP00000388402.2	intact:EBI-2848428|uniprotkb:Q74PX4|uniprotkb:A0A0H2W7W6|uniprotkb:Q7CG52|uniprotkb:A0A384KFS5	psi-mi:tisb_human(display_long)|uniprotkb:EGF-response factor 1(gene name synonym)|uniprotkb:ZFP36L1(gene name)|psi-mi:ZFP36L1(display_short)|uniprotkb:BERG36(gene name synonym)|uniprotkb:BRF1(gene name synonym)|uniprotkb:ERF1(gene name synonym)|uniprotkb:TIS11B(gene name synonym)|uniprotkb:Butyrate response factor 1(gene name synonym)|uniprotkb:RNF162B(gene name synonym)|uniprotkb:Zinc finger protein 36, C3H1 type-like 1(gene name synonym)|uniprotkb:TPA-induced sequence 11b(gene name synonym)	psi-mi:a0a380pl37_yerpe(display_long)|uniprotkb:YPO0421(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852348|imex:IM-13779-5662	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001231630.1|refseq:NP_004917.2|refseq:NP_001231627.1|ensembl:ENSG00000185650.10(gene)|ensembl:ENST00000336440.4(transcript)|ensembl:ENST00000439696.3(transcript)|go:""GO:0000165""(MAPK cascade)|go:""GO:0000288""(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:0000932""(P-body)|go:""GO:0001570""(vasculogenesis)|go:""GO:0003342""(proepicardium development)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0006417""(regulation of translation)|go:""GO:0006915""(apoptotic process)|go:""GO:0007507""(heart development)|go:""GO:0008283""(cell population proliferation)|go:""GO:0009611""(response to wounding)|go:""GO:0010468""(regulation of gene expression)|go:""GO:0010837""(regulation of keratinocyte proliferation)|go:""GO:0021915""(neural tube development)|go:""GO:0031086""(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:""GO:0031440""(regulation of mRNA 3'-end processing)|go:""GO:0032869""(cellular response to insulin stimulus)|go:""GO:0033077""(T cell differentiation in thymus)|go:""GO:0035264""(multicellular organism growth)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0038066""(p38MAPK cascade)|go:""GO:0043488""(regulation of mRNA stability)|go:""GO:0043491""(phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0044344""(cellular response to fibroblast growth factor stimulus)|go:""GO:0045577""(regulation of B cell differentiation)|go:""GO:0045600""(positive regulation of fat cell differentiation)|go:""GO:0045616""(regulation of keratinocyte differentiation)|go:""GO:0045647""(negative regulation of erythrocyte differentiation)|go:""GO:0045657""(positive regulation of monocyte differentiation)|go:""GO:0045661""(regulation of myoblast differentiation)|go:""GO:0046872""(metal ion binding)|go:""GO:0048382""(mesendoderm development)|go:""GO:0051028""(mRNA transport)|go:""GO:0060710""(chorio-allantoic fusion)|go:""GO:0061158""(3'-UTR-mediated mRNA destabilization)|go:""GO:0070371""(ERK1 and ERK2 cascade)|go:""GO:0071320""(cellular response to cAMP)|go:""GO:0071356""(cellular response to tumor necrosis factor)|go:""GO:0071364""(cellular response to epidermal growth factor stimulus)|go:""GO:0071375""(cellular response to peptide hormone stimulus)|go:""GO:0071385""(cellular response to glucocorticoid stimulus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071472""(cellular response to salt stress)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071889""(14-3-3 protein binding)|go:""GO:0072091""(regulation of stem cell proliferation)|go:""GO:0097403""(cellular response to raffinose)|go:""GO:1900153""(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:""GO:1901991""(negative regulation of mitotic cell cycle phase transition)|go:""GO:1902172""(regulation of keratinocyte apoptotic process)|go:""GO:1904582""(positive regulation of intracellular mRNA localization)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR007635(Tis11B like protein, N-terminal)|interpro:IPR036855|interpro:IPR045877|mint:Q07352|rcsb pdb:1W0V|rcsb pdb:1W0W|reactome:R-HSA-450385|panther:PTHR12547(orthology-group)"	"interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR027463|refseq:WP_002209200.1|go:""GO:0005886""(plasma membrane)|go:""GO:0042910""(xenobiotic transmembrane transporter activity)|refseq:YP_002345497.1|panther:PTHR32063(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:J9gDCgiIORuPrUeSmeDvibChS4Y9606	rogid:eNynpfVNIWDaaydEc5eAanQErH8632	intact-crc:B6A8C8733DE83323|rigid:CpnKR44gaSYJxbAPapFr03oW9L0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q5JTD0	uniprotkb:Q8CZM5	intact:EBI-2814077|uniprotkb:Q5JTD1|uniprotkb:Q68DB2|uniprotkb:Q5JWW1|uniprotkb:Q6P2P3|uniprotkb:Q9H7V7|uniprotkb:Q05BH9|ensembl:ENSP00000361522.5|ensembl:ENSP00000361527.1|ensembl:ENSP00000408769.2|intact:EBI-28984091	intact:EBI-2842364	psi-mi:tjap1_human(display_long)|uniprotkb:TJAP1(gene name)|psi-mi:TJAP1(display_short)|uniprotkb:PILT(gene name synonym)|uniprotkb:TJP4(gene name synonym)|uniprotkb:Protein incorporated later into tight junctions(gene name synonym)|uniprotkb:Tight junction protein 4(gene name synonym)	psi-mi:q8czm5_yerpe(display_long)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short)|uniprotkb:y3804(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852334|imex:IM-13779-5660	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:XP_011513297.1|refseq:NP_001139492.1|refseq:NP_542171.2|refseq:NP_001139488.1|refseq:NP_001139489.1|refseq:NP_001139490.1|refseq:NP_001139491.1|refseq:XP_006715322.1|refseq:XP_006715323.1|refseq:XP_006715324.1|refseq:XP_006715325.1|refseq:XP_006715326.1|refseq:XP_006715328.1|refseq:XP_006715329.1|refseq:XP_006715312.1|refseq:XP_006715313.1|refseq:XP_006715314.1|refseq:XP_006715315.1|refseq:XP_006715317.1|refseq:XP_006715319.1|refseq:XP_006715320.1|ensembl:ENSG00000137221.14(gene)|ensembl:ENST00000372445.9(transcript)|ensembl:ENST00000372449.6(transcript)|ensembl:ENST00000438588.6(transcript)|go:""GO:0005768""(endosome)|go:""GO:0005794""(Golgi apparatus)|go:""GO:0005802""(trans-Golgi network)|go:""GO:0005886""(plasma membrane)|go:""GO:0005923""(bicellular tight junction)|go:""GO:0007030""(Golgi organization)|interpro:IPR043441|interpro:IPR043470|mint:Q5JTD0|refseq:XP_016866977.1|refseq:XP_016866978.1|refseq:XP_016866981.1|refseq:XP_016866982.1|refseq:XP_016866979.1|refseq:XP_016866980.1|panther:PTHR28664(orthology-group)"	"interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR027302|interpro:IPR027303|go:""GO:0004356""(glutamine synthetase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006542""(glutamine biosynthetic process)|interpro:IPR036651"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Rn4TPVz2INwUzgJ7MGJ9CKHYaaM9606	rogid:1UHMOyirOEgP8E+d/TNK/YRPS+4632	intact-crc:57935B971799B197|rigid:CYqcbhjTxLO7XbBnstn/CgZbnBw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9GZM7	uniprotkb:Q65AE7	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	intact:EBI-2847916|uniprotkb:A0A3N4BMH0|uniprotkb:Q9ZGZ5|uniprotkb:A0A384LBG0|uniprotkb:A0A1U8QRS1|uniprotkb:Q7ARB3	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	psi-mi:q65ae7_yerpe(display_long)|uniprotkb:YPMT1.73(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852384|imex:IM-13779-5666	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"interpro:IPR025202|refseq:WP_002211757.1|refseq:NP_395419.1|refseq:YP_094002.1|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|go:""GO:0006793""(phosphorus metabolic process)|go:""GO:0016042""(lipid catabolic process)|go:""GO:0016787""(hydrolase activity)|interpro:IPR051406"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	rogid:BaOKn4oWF9wcKgOoNSaPk58oQ6k632	intact-crc:C11B02D7748070D0|rigid:SXkR81HuoN2YgIT6c8w/29j80eU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJJ7	uniprotkb:Q9GZM7	intact:EBI-2842396|uniprotkb:Q0WKJ5	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:rraa_yerpe(display_long)|uniprotkb:rraA(gene name)|psi-mi:rraA(display_short)|uniprotkb:menG(gene name synonym)|uniprotkb:YPO0103(locus name)|uniprotkb:y0292(locus name)|uniprotkb:YP_0105(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852377|imex:IM-13779-5665	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR005493(Ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase)|interpro:IPR014339(Ribonuclease E inhibitor RraA, gammaproteobacteria)|interpro:IPR010203(Ribonuclease E inhibitor RraA)|go:""GO:0005829""(cytosol)|go:""GO:0019899""(enzyme binding)|go:""GO:0060698""(endoribonuclease inhibitor activity)|go:""GO:1902369""(negative regulation of RNA catabolic process)|refseq:WP_002208945.1|interpro:IPR036704|refseq:YP_002345193.1|panther:PTHR33254(orthology-group)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:x8Fy09KliIuc6AQIzPt6slnvUic632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:D927D86CDA8303C1|rigid:1LZLp5mKVqXZbuB45qxcbNAO7Oo	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9GZM7	uniprotkb:Q8D1P4	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	intact:EBI-2845144	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	psi-mi:q8d1p4_yerpe(display_long)|uniprotkb:y0195(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852391|imex:IM-13779-5669	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	interpro:IPR032712|interpro:IPR025263|interpro:IPR011836(Conserved hypothetical protein CHP02099)	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	rogid:k1ALZgWrTdqeyJ1mZBZgusKWD8Y632	intact-crc:D03360D2DA61834C|rigid:J6D89uO0G6wAo37JbFlXtpu2840	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9GZM7	uniprotkb:Q0WEG0	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	intact:EBI-2852405|uniprotkb:Q74TK5|uniprotkb:Q8D0L2	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	psi-mi:dtpa_yerpe(display_long)|uniprotkb:dtpA(gene name)|psi-mi:dtpA(display_short)|uniprotkb:YPO2361(locus name)|uniprotkb:y1971(locus name)|uniprotkb:YP_2150(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852410|imex:IM-13779-5667	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"interpro:IPR005279(Amino acid/peptide transporter)|interpro:IPR023517|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|refseq:WP_002215910.1|go:""GO:0005886""(plasma membrane)|go:""GO:0015031""(protein transport)|go:""GO:0015333""(""peptide:proton symporter activity"")|go:""GO:0035442""(dipeptide transmembrane transport)|go:""GO:0042937""(tripeptide transmembrane transporter activity)|go:""GO:0071916""(dipeptide transmembrane transporter activity)|interpro:IPR036259|refseq:YP_002347328.1|interpro:IPR050171|panther:PTHR11654(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	rogid:gEpBGaVxVR9kmhEMY33xLTqsPAM632	intact-crc:6310C2BA53163424|rigid:+D+OCuLIeZMPmZP1/6QZIo/BZ/U	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8D1M8	uniprotkb:Q9GZM7	intact:EBI-2843956	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:q8d1m8_yerpe(display_long)|uniprotkb:y0257(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852398|imex:IM-13779-5668	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)|interpro:IPR050708	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:CV6eFVldIgYFQRKvjlqv9/IE4do632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:081E60D2D9F3826C|rigid:20y4QGI/08zdK6luoShi/3Dz8PE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CWI4	uniprotkb:Q9GZM7	intact:EBI-2841215	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:q8cwi4_yerpe(display_long)|uniprotkb:kbl(gene name)|psi-mi:kbl(display_short)|uniprotkb:Glycine acetyltransferase(gene name synonym)|uniprotkb:y0081(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852417|imex:IM-13779-5670	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR011282(2-amino-3-ketobutyrate coenzyme A ligase)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|go:""GO:0008890""(glycine C-acetyltransferase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0016874""(ligase activity)|go:""GO:0019518""(L-threonine catabolic process to glycine)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR050087"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:uETD2R/0GvIqPvz6yt39/YuJzJQ632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:827B1485DA66E14B|rigid:w3PwEMov1L1r9aBZXJsqrwCTQrE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9GZM7	uniprotkb:Q7CK09	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	intact:EBI-2851418|uniprotkb:Q7B0V6|uniprotkb:Q74WP0|uniprotkb:Q0WCG5|uniprotkb:A0A5P8YIG7	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	psi-mi:q7ck09_yerpe(display_long)|uniprotkb:ddhA(gene name)|psi-mi:ddhA(display_short)|uniprotkb:YPO3115(locus name)|uniprotkb:rfbF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852445|imex:IM-13779-5672	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"interpro:IPR029044|interpro:IPR013446(Glucose-1-phosphate cytidylyltransferase)|interpro:IPR005835(Nucleotidyl transferase)|go:""GO:0009243""(O antigen biosynthetic process)|go:""GO:0047343""(glucose-1-phosphate cytidylyltransferase activity)|refseq:YP_002348023.1|interpro:IPR046981|panther:PTHR47183(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	rogid:TBBjggvwoVzR1lBlAwLFQUWZ5nk632	intact-crc:780BFC7C06BE556A|rigid:7DUlUlNAf7AeoJZs4OJuXPJBrjQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3G5LBX8	uniprotkb:Q9GZM7	intact:EBI-2848086	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:a0a3g5lbx8_yerpe(display_long)|uniprotkb:y3412(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852431|imex:IM-13779-5674	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	uniprotkb:A0A5P8YIY0(uniprot-removed-ac)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR010071(Amino acid adenylation)|interpro:IPR020845|interpro:IPR036736|interpro:IPR042099|interpro:IPR045851|refseq:WP_002214915.1	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nRnMFya58I5DJrYEbqwkzL8Fl6o632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:1EC883F498FE1407|rigid:m1oYfinbI20olN2ngbUDtt1PiJY	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CKW7	uniprotkb:Q9GZM7	intact:EBI-2845318	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:q8ckw7_yerpe(display_long)|uniprotkb:y2698(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852424|imex:IM-13779-5671	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	refseq:WP_002231240.1|interpro:IPR028244|interpro:IPR018769|interpro:IPR006533(Rhs element Vgr protein)|interpro:IPR017847(Rhs element Vgr protein, subgroup)|interpro:IPR037026|interpro:IPR006531(Phage baseplate assembly protein V)	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Nrvz9YxMF2TgzN5e3ZNazVacK34632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:BA8C4885DA850494|rigid:gGDZ4FTtlJbgnzscF4LFQWMM94k	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A3N4B6L4	uniprotkb:Q9GZM7	intact:EBI-2843521|uniprotkb:Q74R92|uniprotkb:Q0WAE3|uniprotkb:Q7CKZ2|uniprotkb:A0A384KL30	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:a0a3n4b6l4_yerpe(display_long)|uniprotkb:psuA(gene name synonym)|uniprotkb:rnsC(gene name synonym)|uniprotkb:sbaA(gene name synonym)|uniprotkb:tsu(gene name synonym)|uniprotkb:ATP-dependent helicase Rho(gene name synonym)|uniprotkb:rho(gene name synonym)|uniprotkb:nitA(gene name)|psi-mi:nitA(display_short)|uniprotkb:YPO3867(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852438|imex:IM-13779-5673	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR011112(Rho termination factor, N-terminal)|interpro:IPR011113(Rho termination factor, RNA-binding)|interpro:IPR004665(Transcription termination factor Rho)|interpro:IPR027417|go:""GO:0003723""(RNA binding)|go:""GO:0004386""(helicase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005829""(cytosol)|go:""GO:0006353""(DNA-templated transcription termination)|go:""GO:0008186""(ATP-dependent activity, acting on RNA)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002211989.1|interpro:IPR036269|interpro:IPR041703|refseq:YP_002348745.1|panther:PTHR46425(orthology-group)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:d6NkDZjvNCwgkhXxhvckAvDrcJE632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:68E818BCBA8BD815|rigid:ypoautRiMIKkWY/6dRLFCxh4dSk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9GZM7	uniprotkb:A0A380PFG3	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	intact:EBI-2844399|uniprotkb:Q0WCT9|uniprotkb:Q7CJE7	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	psi-mi:a0a380pfg3_yerpe(display_long)|uniprotkb:YPO2975(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852466|imex:IM-13779-5679	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_002211613.1|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|refseq:YP_002347899.1|interpro:IPR050881|panther:PTHR42832(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	rogid:gxs4oIww4YLZ4JkmmT+hmD0ULQM632	intact-crc:F541A4A5D01C627E|rigid:Wh35S+tfNPRyVL6MHROy+KKiKgs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GVZ6	uniprotkb:Q9GZM7	intact:EBI-2842971|uniprotkb:Q74W16|uniprotkb:A0A0H2W2X1|uniprotkb:Q7CJU6|uniprotkb:A0A3N4AZS9|uniprotkb:A0A384L7G7	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:a0a2u2gvz6_yerpe(display_long)|uniprotkb:ubiF(gene name)|psi-mi:ubiF(display_short)|uniprotkb:YPO2621(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852452|imex:IM-13779-5675	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR010971(Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6)|go:""GO:0004497""(monooxygenase activity)|go:""GO:0006744""(ubiquinone biosynthetic process)|go:""GO:0016705""(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:""GO:0071949""(FAD binding)|refseq:WP_002210347.1|interpro:IPR036188|refseq:YP_002347577.1|interpro:IPR051205"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:zKOVHd4RmzcakJDi4rlK0Xy9yNc632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:F3FF3668644B7550|rigid:Uq6Edo/22lneKd+M4t7J+QjBmFg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A380SAV6	uniprotkb:Q9GZM7	intact:EBI-2844158|uniprotkb:Q0WEB4|uniprotkb:Q7CIT4|uniprotkb:A0A384LPZ8	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:a0a380sav6_yerpe(display_long)|uniprotkb:ppsA(gene name synonym)|uniprotkb:pps(gene name)|psi-mi:pps(display_short)|uniprotkb:Pyruvate, water dikinase(gene name synonym)|uniprotkb:YPO2409(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852473|imex:IM-13779-5678	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR006319(Phosphoenolpyruvate synthase)|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR002192(Pyruvate phosphate dikinase, PEP/pyruvate-binding)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018274|interpro:IPR023151|go:""GO:0005524""(ATP binding)|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006094""(gluconeogenesis)|go:""GO:0008986""(pyruvate, water dikinase activity)|go:""GO:0046872""(metal ion binding)|refseq:WP_002211813.1|interpro:IPR040442|interpro:IPR036637|refseq:YP_002347374.1|panther:PTHR43030(orthology-group)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:nQ2ifmi7FAK38H5Y8B/dF0x0e1s632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:88D6B304D9B81ED4|rigid:SIoZkA5wxcW7kTVLAYsKgJVMVgw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9GZM7	uniprotkb:A0A2U2GZS7	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	intact:EBI-2843433|uniprotkb:Q74W70|uniprotkb:A0A0H2W1T5|uniprotkb:Q7CH58|uniprotkb:A0A3N4B3M4|uniprotkb:A0A384LC90	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	psi-mi:a0a2u2gzs7_yerpe(display_long)|uniprotkb:galB(gene name)|psi-mi:galB(display_short)|uniprotkb:galT(gene name synonym)|uniprotkb:YPO1138(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852480|imex:IM-13779-5677	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"interpro:IPR001937(Galactose-1-phosphate uridyl transferase, class I)|interpro:IPR005850(Galactose-1-phosphate uridyl transferase, C-terminal)|interpro:IPR005849(Galactose-1-phosphate uridyl transferase, N-terminal)|interpro:IPR019779|go:""GO:0006012""(galactose metabolic process)|go:""GO:0008108""(""UDP-glucose:hexose-1-phosphate uridylyltransferase activity"")|go:""GO:0008270""(zinc ion binding)|refseq:WP_002210749.1|interpro:IPR036265|refseq:YP_002346178.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	rogid:1wWEGW8F2ZvDmG2/gCGCjsXVXE4632	intact-crc:F10F4CF0C532ADBD|rigid:hZr9Ls0NCSh+rZVDwT8gH+NzJaM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9GZM7	uniprotkb:A0A2S9PJ11	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	intact:EBI-2843240|uniprotkb:Q74SW1|uniprotkb:Q7CJT3|uniprotkb:A0A380PL96|uniprotkb:Q0WDP0	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	psi-mi:a0a2s9pj11_yerpe(display_long)|uniprotkb:proW(gene name)|psi-mi:proW(display_short)|uniprotkb:YPO2646(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852459|imex:IM-13779-5676	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|go:""GO:0005886""(plasma membrane)|go:""GO:0055085""(transmembrane transport)|refseq:WP_002212209.1|interpro:IPR035906|refseq:YP_002347598.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	rogid:BBwCIsPUr1k5paTb1ggfStKFewc632	intact-crc:DDF18094C05FEF4C|rigid:TWsUmGZ5kysD40G1ohCXVPswQSM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WIJ7	uniprotkb:Q9GZM7	intact:EBI-2851185|uniprotkb:Q74QE7|uniprotkb:A0A0H2W874|uniprotkb:A0A3N4B4F6|uniprotkb:Q7CGW9|uniprotkb:A0A384LBF7	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:q0wij7_yerpe(display_long)|uniprotkb:YPO0840(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852487|imex:IM-13779-5680	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010905(Glycosyl hydrolase, family 88)|refseq:WP_002209884.1|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR012341(Six-hairpin glycosidase)|refseq:YP_002345891.1|interpro:IPR052043"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:OJNnsHqKxXDsmBDCvDpKtYoti2k632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:62B38EBA52830327|rigid:hxtx1RtHujF9RU24wc0yc2YYPJE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZCQ2	uniprotkb:Q9GZM7	intact:EBI-2850142|uniprotkb:Q0WCY7	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:pur4_yerpe(display_long)|uniprotkb:purL(gene name)|psi-mi:purL(display_short)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)|uniprotkb:YPO2921(locus name)|uniprotkb:YP_2536(locus name)|uniprotkb:y1309(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852520|imex:IM-13779-5682	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR029062|refseq:WP_002211561.1|interpro:IPR040707|go:""GO:0004642""(phosphoribosylformylglycinamidine synthase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006164""(purine nucleotide biosynthetic process)|go:""GO:0006189""('de novo' IMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR055181|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR041609|refseq:YP_002347851.1|panther:PTHR10099(orthology-group)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:8JTbD5hWDWC5PK7sHtiOwqqdyHs632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:811A216CDBABCEEB|rigid:PqfWW168f4kFVs8kDfJ8IM8BSHw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9GZM7	uniprotkb:Q0WJ53	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	intact:EBI-2841146|uniprotkb:A0A0H2W7L9|uniprotkb:Q74RT3|uniprotkb:Q7CGF0|uniprotkb:A0A380PMR6	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	psi-mi:q0wj53_yerpe(display_long)|uniprotkb:YPO0616(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852494|imex:IM-13779-5681	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"refseq:YP_002345685.1|interpro:IPR002772(Glycoside hydrolase, family 3, C-terminal)|interpro:IPR001764(Glycoside hydrolase, family 3, N-terminal)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR026891|go:""GO:0004553""(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:""GO:0005975""(carbohydrate metabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036881|interpro:IPR036962|refseq:WP_002210379.1|interpro:IPR051915"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	rogid:NIeb7qLRqloPp0rZ/Uu04q0TwMU632	intact-crc:855B1DBA53E17F09|rigid:rfVy8Swa9/cakLhjcDilfXufkzc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q7ARN5	uniprotkb:Q9GZM7	intact:EBI-2839967|uniprotkb:Q7CKL5|uniprotkb:Q74YZ9|uniprotkb:Q7ARK5|uniprotkb:Q7BTY3|uniprotkb:Q7BT06|uniprotkb:A0A1U8QKK8|uniprotkb:A0A3G5LBZ8|uniprotkb:A0A3G5L3F7	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:q7arn5_yerpe(display_long)|uniprotkb:ypmt1(gene name synonym)|uniprotkb:YPCD1.01(locus name)|uniprotkb:YPMT1.01(locus name)|uniprotkb:YPMT1.58c(locus name)|uniprotkb:YPPCP1.01(locus name)|uniprotkb:y1093(gene name)|psi-mi:y1093(display_short)|uniprotkb:YPO0031(locus name)|uniprotkb:YPO0171(locus name)|uniprotkb:YPO0249(locus name)|uniprotkb:YPO0386(locus name)|uniprotkb:YPO0528(locus name)|uniprotkb:YPO0567(locus name)|uniprotkb:YPO0637(locus name)|uniprotkb:YPO0780(locus name)|uniprotkb:YPO0826(locus name)|uniprotkb:YPO0924(locus name)|uniprotkb:YPO1013(locus name)|uniprotkb:YPO1086(locus name)|uniprotkb:YPO1132(locus name)|uniprotkb:YPO1338(locus name)|uniprotkb:YPO1427(locus name)|uniprotkb:YPO1520(locus name)|uniprotkb:YPO1623(locus name)|uniprotkb:YPO1692(locus name)|uniprotkb:YPO1729(locus name)|uniprotkb:YPO1750(locus name)|uniprotkb:YPO1900(locus name)|uniprotkb:YPO2026(locus name)|uniprotkb:YPO2085(locus name)|uniprotkb:YPO2178(locus name)|uniprotkb:YPO2365(locus name)|uniprotkb:YPO2396(locus name)|uniprotkb:YPO2516(locus name)|uniprotkb:YPO2643(locus name)|uniprotkb:YPO2721(locus name)|uniprotkb:YPO2808(locus name)|uniprotkb:YPO2932(locus name)|uniprotkb:YPO3209(locus name)|uniprotkb:YPO3251(locus name)|uniprotkb:YPO3282(locus name)|uniprotkb:YPO3434(locus name)|uniprotkb:YPO3542(locus name)|uniprotkb:YPO3591(locus name)|uniprotkb:YPO3701(locus name)|uniprotkb:YPO3756(locus name)|uniprotkb:YPO3774(locus name)|uniprotkb:YPO4010(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852513|imex:IM-13779-5683	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:YP_002348636.1|refseq:YP_002348652.1|refseq:YP_002348877.1|interpro:IPR017894|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:NP_395138.1|refseq:NP_395227.1|refseq:NP_395336.1|refseq:NP_395402.1|refseq:NP_857638.1|refseq:NP_857716.1|refseq:NP_857780.1|refseq:YP_094025.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR036397|refseq:WP_000255944.1|refseq:YP_006960969.1|go:""GO:0000150""(DNA strand exchange activity)|go:""GO:0003677""(DNA binding)|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)|go:""GO:0015074""(DNA integration)|go:""GO:0032196""(transposition)|interpro:IPR006120(Resolvase, helix-turn-helix region)|refseq:YP_002345127.1|refseq:YP_002345256.1|refseq:YP_002345330.1|refseq:YP_002345463.1|refseq:YP_002345601.1|refseq:YP_002345638.1|refseq:YP_002345704.1|refseq:YP_002345836.1|refseq:YP_002345880.1|refseq:YP_002345972.1|refseq:YP_002346056.1|refseq:YP_002346129.1|refseq:YP_002346174.1|refseq:YP_002346362.1|refseq:YP_002346450.1|refseq:YP_002346536.1|refseq:YP_002346634.1|refseq:YP_002346730.1|refseq:YP_002346750.1|refseq:YP_002346890.1|refseq:YP_002347010.1|refseq:YP_002347066.1|refseq:YP_002347152.1|refseq:YP_002347332.1|refseq:YP_002347362.1|refseq:YP_002347480.1|refseq:YP_002347596.1|refseq:YP_002347668.1|refseq:YP_002347749.1|refseq:YP_002347862.1|refseq:YP_002348112.1|refseq:YP_002348152.1|refseq:YP_002348181.1|refseq:YP_002348326.1|refseq:YP_002348430.1|refseq:YP_002348476.1|refseq:YP_002346695.1|refseq:YP_002348583.1|panther:PTHR35004(orthology-group)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:gYoFpz6mpcJ4NYVEafsAkK14EIE632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:69B5AF9E053B89E1|rigid:NtSMTDYd3UE7ua+uH2hbV9RVeso	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PLB3	uniprotkb:Q9GZM7	intact:EBI-2852501|uniprotkb:Q74Q16|uniprotkb:Q0WJJ2|uniprotkb:Q7CG79|uniprotkb:A0A384LE02	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:a0a2s9plb3_yerpe(display_long)|uniprotkb:b0025(gene name)|psi-mi:b0025(display_short)|uniprotkb:ribF(gene name synonym)|uniprotkb:YPO0474(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852506|imex:IM-13779-5684	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002210510.1|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR015864(FAD synthetase)|interpro:IPR023468|interpro:IPR002606(Riboflavin kinase/FAD synthetase)|interpro:IPR015865(Riboflavin kinase)|interpro:IPR023465|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|go:""GO:0003919""(FMN adenylyltransferase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0006747""(FAD biosynthetic process)|go:""GO:0006771""(riboflavin metabolic process)|go:""GO:0008531""(riboflavin kinase activity)|go:""GO:0009231""(riboflavin biosynthetic process)|go:""GO:0009398""(FMN biosynthetic process)|refseq:YP_002345546.1|panther:PTHR22749(orthology-group)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0cLBPOUE8nJw1J+/mrY5ir7KpXU632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:BDA4ADBD2D3B662A|rigid:AuPVrGCqxiWuCgbxOKaP16mfXq0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PID6	uniprotkb:Q02763	intact:EBI-2852541|uniprotkb:Q7CJ99|uniprotkb:Q0WDA9	intact:EBI-2257090|ensembl:ENSP00000369375.4|uniprotkb:A8K6W0|uniprotkb:Q5TCU2|uniprotkb:B4DH20|uniprotkb:B4DHD3|uniprotkb:E7EWI2|uniprotkb:Q8IV34|uniprotkb:D3DRK5	psi-mi:a0a2s9pid6_yerpe(display_long)|uniprotkb:Ascorbate-specific permease IIC component UlaA(gene name synonym)|uniprotkb:YPO2782(locus name)	psi-mi:tie2_human(display_long)|uniprotkb:TEK(gene name)|psi-mi:TEK(display_short)|uniprotkb:TIE2(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor TIE-2(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor TEK(gene name synonym)|uniprotkb:Tunica interna endothelial cell kinase(gene name synonym)|uniprotkb:p140 TEK(gene name synonym)|uniprotkb:Endothelial tyrosine kinase(gene name synonym)|uniprotkb:Tyrosine kinase with Ig and EGF homology domains-2(gene name synonym)|uniprotkb:VMCM(gene name synonym)|uniprotkb:VMCM1(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852544|imex:IM-13779-5689	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR051562|interpro:IPR004703(Phosphotransferase system, galactitol-specific IIC component)|refseq:WP_002222248.1|go:""GO:0005886""(plasma membrane)|go:""GO:0009401""(phosphoenolpyruvate-dependent sugar phosphotransferase system)|refseq:YP_002347729.1|panther:PTHR33843(orthology-group)"	"ensembl:ENSG00000120156.22(gene)|ensembl:ENST00000380036.10(transcript)|go:""GO:0001525""(angiogenesis)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001934""(positive regulation of protein phosphorylation)|go:""GO:0001935""(endothelial cell proliferation)|go:""GO:0001938""(positive regulation of endothelial cell proliferation)|go:""GO:0001958""(endochondral ossification)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0004672""(protein kinase activity)|go:""GO:0004714""(transmembrane receptor protein tyrosine kinase activity)|go:""GO:0005004""(GPI-linked ephrin receptor activity)|go:""GO:0005005""(transmembrane-ephrin receptor activity)|go:""GO:0005006""(epidermal growth factor receptor activity)|go:""GO:0005007""(fibroblast growth factor receptor activity)|go:""GO:0005008""(hepatocyte growth factor receptor activity)|go:""GO:0005009""(insulin receptor activity)|go:""GO:0005010""(insulin-like growth factor receptor activity)|go:""GO:0005011""(macrophage colony-stimulating factor receptor activity)|go:""GO:0005018""(platelet-derived growth factor alpha-receptor activity)|go:""GO:0005019""(platelet-derived growth factor beta-receptor activity)|go:""GO:0005020""(stem cell factor receptor activity)|go:""GO:0005021""(vascular endothelial growth factor receptor activity)|go:""GO:0005524""(ATP binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005737""(cytoplasm)|go:""GO:0005886""(plasma membrane)|go:""GO:0005902""(microvillus)|go:""GO:0005911""(cell-cell junction)|go:""GO:0005925""(focal adhesion)|go:""GO:0007169""(cell surface receptor protein tyrosine kinase signaling pathway)|go:""GO:0007267""(cell-cell signaling)|go:""GO:0007507""(heart development)|go:""GO:0008288""(boss receptor activity)|go:""GO:0009925""(basal plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010595""(positive regulation of endothelial cell migration)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016324""(apical plasma membrane)|go:""GO:0016525""(negative regulation of angiogenesis)|go:""GO:0019838""(growth factor binding)|go:""GO:0032878""(regulation of establishment or maintenance of cell polarity)|go:""GO:0034446""(substrate adhesion-dependent cell spreading)|go:""GO:0034451""(centriolar satellite)|go:""GO:0035022""(positive regulation of Rac protein signal transduction)|go:""GO:0035025""(positive regulation of Rho protein signal transduction)|go:""GO:0035401""(histone H3Y41 kinase activity)|go:""GO:0036332""(placental growth factor receptor activity)|go:""GO:0038023""(signaling receptor activity)|go:""GO:0038062""(protein tyrosine kinase collagen receptor activity)|go:""GO:0042802""(identical protein binding)|go:""GO:0043066""(negative regulation of apoptotic process)|go:""GO:0043114""(regulation of vascular permeability)|go:""GO:0043235""(receptor complex)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043627""(response to estrogen)|go:""GO:0045121""(membrane raft)|go:""GO:0045766""(positive regulation of angiogenesis)|go:""GO:0048014""(Tie signaling pathway)|go:""GO:0050728""(negative regulation of inflammatory response)|go:""GO:0051591""(response to cAMP)|go:""GO:0051894""(positive regulation of focal adhesion assembly)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060175""(brain-derived neurotrophic factor receptor activity)|go:""GO:0060216""(definitive hemopoiesis)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0072012""(glomerulus vasculature development)|go:""GO:0140801""(histone H2AXY142 kinase activity)|go:""GO:1902533""(positive regulation of intracellular signal transduction)|go:""GO:2000351""(regulation of endothelial cell apoptotic process)|go:""GO:2000352""(negative regulation of endothelial cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018941|interpro:IPR020635|interpro:IPR036116|interpro:IPR036179|interpro:IPR050122|mint:Q02763|rcsb pdb:1FVR|rcsb pdb:2GY5|rcsb pdb:2GY7|rcsb pdb:2OO8|rcsb pdb:2OSC|rcsb pdb:2P4I|rcsb pdb:2WQB|rcsb pdb:3BEA|rcsb pdb:3L8P|rcsb pdb:4K0V|rcsb pdb:4X3J|rcsb pdb:5MYA|rcsb pdb:5MYB|rcsb pdb:5UTK|rcsb pdb:6MWE|rcsb pdb:7E72|reactome:R-HSA-210993|reactome:R-HSA-5673001|refseq:NP_000450.2|refseq:NP_001277006.1|refseq:NP_001277007.1|dip:DIP-6047N|efo:""Orphanet:1059""|efo:""Orphanet:2451""|efo:""Orphanet:98976""|panther:PTHR24416(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:HGM5YqpTTcqbe/pNI0T33Mxne/w632	rogid:iZHZ6RvLXT65o6FTQaHW+cnrX1o9606	intact-crc:01F68B3983BEA9CD|rigid:vWmToDKk/89MjwokbqCIHzMiwfU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJ16	uniprotkb:Q9GZM7	intact:EBI-2841852|uniprotkb:Q0WJZ3	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	psi-mi:lexa_yerpe(display_long)|uniprotkb:lexA(gene name)|psi-mi:lexA(display_short)|uniprotkb:YPO0314(locus name)|uniprotkb:y0572(locus name)|uniprotkb:YP_0470(locus name)	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852534|imex:IM-13779-5686	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR039418|interpro:IPR006199(LexA DNA-binding region)|interpro:IPR006200(Peptidase S24, LexA repressor)|interpro:IPR006197(Peptidase S24, LexA/MucA/RumA/RuvA)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|go:""GO:0003677""(DNA binding)|go:""GO:0004252""(serine-type endopeptidase activity)|go:""GO:0006260""(DNA replication)|go:""GO:0006281""(DNA repair)|go:""GO:0006508""(proteolysis)|go:""GO:0009432""(SOS response)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|refseq:YP_002345395.1|refseq:WP_002209090.1|interpro:IPR036286|interpro:IPR036388|interpro:IPR036390|interpro:IPR050077|panther:PTHR33516(orthology-group)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1RBPmARbsfVEavq4/r0MVDBH/Og632	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	intact-crc:4F6CD86CDACF0E6B|rigid:eh4TvbV08xpkQd7J309w3RWdreU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q01085	uniprotkb:Q8D0D4	intact:EBI-2820828|uniprotkb:A8K3T0|uniprotkb:A8K4L9|ensembl:ENSP00000394902.2	intact:EBI-2847212	psi-mi:tiar_human(display_long)|uniprotkb:TIAL1(gene name)|psi-mi:TIAL1(display_short)|uniprotkb:TIA-1-related protein(gene name synonym)	psi-mi:q8d0d4_yerpe(display_long)|uniprotkb:hmsH(gene name)|psi-mi:hmsH(display_short)|uniprotkb:y2359(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852551|imex:IM-13779-5688	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001029097.1|refseq:NP_003243.1|ensembl:ENSG00000151923.18(gene)|ensembl:ENST00000436547.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006952""(defense response)|go:""GO:0007281""(germ cell development)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017145""(stem cell division)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0044194""(cytolytic granule)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0140517""(protein-RNA adaptor activity)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|go:""GO:2000648""(positive regulation of stem cell proliferation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034492|interpro:IPR034494|interpro:IPR034496|interpro:IPR035979|mint:Q01085|rcsb pdb:1X4G|rcsb pdb:2CQI|rcsb pdb:2DH7|reactome:R-HSA-6803529|dip:DIP-42425N|panther:PTHR10352(orthology-group)"	"interpro:IPR023870|interpro:IPR011990(Tetratricopeptide-like helical)|go:""GO:1901515""(poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity)|interpro:IPR049003"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:dKWzIWmR/JaCJwsOLUPG2Z1uhH89606	rogid:oBs/IRM9/gKecuXNw9IoCZLu4Vw632	intact-crc:B270DE98A5D9A225|rigid:UyIjrIBPlhfBWIGTvR7c4vztFYU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9GZM7	uniprotkb:P58497	intact:EBI-715869|uniprotkb:Q8TEJ9|uniprotkb:Q8WZ23|uniprotkb:Q96GZ4|uniprotkb:Q96JW3|uniprotkb:A8K9Q5|uniprotkb:D3DPN8|uniprotkb:B4DPK6|ensembl:ENSP00000271064.7	intact:EBI-2840431|uniprotkb:Q0WHQ6	psi-mi:tinal_human(display_long)|uniprotkb:Tubulointerstitial nephritis antigen-related protein(gene name synonym)|uniprotkb:Glucocorticoid-inducible protein 5(gene name synonym)|uniprotkb:Oxidized LDL-responsive gene 2 protein(gene name synonym)|uniprotkb:PSEC0088(orf name)|uniprotkb:UNQ204/PRO230(orf name)|uniprotkb:TINAGL1(gene name)|psi-mi:TINAGL1(display_short)|uniprotkb:GIS5(gene name synonym)|uniprotkb:LCN7(gene name synonym)|uniprotkb:OLRG2(gene name synonym)|uniprotkb:TINAGL(gene name synonym)|uniprotkb:PP6614(orf name)	psi-mi:mode_yerpe(display_long)|uniprotkb:modE(gene name)|psi-mi:modE(display_short)|uniprotkb:YPO1143(locus name)|uniprotkb:y3040(locus name)|uniprotkb:YP_1017(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852527|imex:IM-13779-5685	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001191343.1|refseq:NP_001191344.1|refseq:NP_071447.1|ensembl:ENSG00000142910.16(gene)|ensembl:ENST00000271064.12(transcript)|go:""GO:0005201""(extracellular matrix structural constituent)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005737""(cytoplasm)|go:""GO:0016197""(endosomal transport)|go:""GO:0043236""(laminin binding)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070062""(extracellular exosome)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR001212(Somatomedin B)|interpro:IPR013128(Peptidase C1A, papain)|interpro:IPR025660|interpro:IPR038765|mint:Q9GZM7|panther:PTHR12411(orthology-group)"	"interpro:IPR005116(Transport-associated OB, type 1)|interpro:IPR004606(Molybdenum-pterin binding)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR003725(Molybdenum-binding protein, N-terminal)|interpro:IPR016462(Molybdate-dependent transcriptional regulator, ModE)|go:""GO:0003677""(DNA binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006355""(regulation of DNA-templated transcription)|go:""GO:0015689""(molybdate ion transport)|go:""GO:0030151""(molybdenum ion binding)|refseq:WP_002210754.1|refseq:YP_002346182.1|interpro:IPR036388|interpro:IPR036390|interpro:IPR051815|panther:PTHR30432(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0aLWvxXSLPKiQeP4kKMwn3/bL0E9606	rogid:UOXc5L3bZSzLOIuq9x/17/AMHmM632	intact-crc:C4B4A95D3AE00723|rigid:YosuKGB8ylBbLrqKEcmMrqhbyf4	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A0H2W203	uniprotkb:Q01085	intact:EBI-2852558|uniprotkb:Q74VZ6|uniprotkb:Q7CJV9|uniprotkb:Q0WDU0	intact:EBI-2820828|uniprotkb:A8K3T0|uniprotkb:A8K4L9|ensembl:ENSP00000394902.2	psi-mi:a0a0h2w203_yerpe(display_long)|uniprotkb:YPO2592(locus name)	psi-mi:tiar_human(display_long)|uniprotkb:TIAL1(gene name)|psi-mi:TIAL1(display_short)|uniprotkb:TIA-1-related protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852562|imex:IM-13779-5687	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:WP_002210312.1|go:""GO:0016747""(acyltransferase activity, transferring groups other than amino-acyl groups)|interpro:IPR002656(Acyltransferase 3)|refseq:YP_002347548.1"	"refseq:NP_001029097.1|refseq:NP_003243.1|ensembl:ENSG00000151923.18(gene)|ensembl:ENST00000436547.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006952""(defense response)|go:""GO:0007281""(germ cell development)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017145""(stem cell division)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0044194""(cytolytic granule)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0140517""(protein-RNA adaptor activity)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|go:""GO:2000648""(positive regulation of stem cell proliferation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034492|interpro:IPR034494|interpro:IPR034496|interpro:IPR035979|mint:Q01085|rcsb pdb:1X4G|rcsb pdb:2CQI|rcsb pdb:2DH7|reactome:R-HSA-6803529|dip:DIP-42425N|panther:PTHR10352(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:aMP8CwBIR17xcgNv6uhxL2gnfBc632	rogid:dKWzIWmR/JaCJwsOLUPG2Z1uhH89606	intact-crc:760C5021DF4AD906|rigid:Tsj0wsyJpeOwtQJDn29Kz9t7av0	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31483	uniprotkb:A0A2U2H1X7	intact:EBI-1387216|uniprotkb:Q53SS9|uniprotkb:Q96B58|ensembl:ENSP00000401371.2	intact:EBI-2852588|uniprotkb:A0A5P8YLP8|uniprotkb:O68761|uniprotkb:Q74YL1|uniprotkb:A0A0H2W1W6|uniprotkb:A0A384KIL8|uniprotkb:A0A1U8QXV7|uniprotkb:Q7ARD2	psi-mi:tia1_human(display_long)|uniprotkb:TIA1(gene name)|psi-mi:TIA1(display_short)|uniprotkb:p40-TIA-1(gene name synonym)|uniprotkb:RNA-binding protein TIA-1(gene name synonym)|uniprotkb:T-cell-restricted intracellular antigen-1(gene name synonym)|uniprotkb:Nucleolysin TIA-1 isoform p40(gene name synonym)	psi-mi:a0a2u2h1x7_yerpe(display_long)|uniprotkb:YPMT1.46c(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852592|imex:IM-13779-5694	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000116001.17(gene)|ensembl:ENST00000433529.7(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0006915""(apoptotic process)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0034063""(stress granule assembly)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0097165""(nuclear stress granule)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034496|interpro:IPR034827|interpro:IPR034830|interpro:IPR035979|mint:P31483|rcsb pdb:2MJN|rcsb pdb:3BS9|rcsb pdb:5ITH|rcsb pdb:5O2V|rcsb pdb:5O3J|rcsb pdb:6ELD|rcsb pdb:7VI4|rcsb pdb:7VI5|reactome:R-HSA-6803529|refseq:NP_071320.2|refseq:NP_071505.2|panther:PTHR10352(orthology-group)|efo:""Orphanet:603"""	"refseq:NP_395387.1|refseq:YP_093932.1|refseq:WP_002227818.1|go:""GO:0004519""(endonuclease activity)|go:""GO:0004527""(exonuclease activity)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:d2ecwJo5sjSY6a/By3GM3B5A6PE9606	rogid:ECV8TsPwvYxkvQ0RlSW3E0ZubiI632	intact-crc:CCD684863296711D|rigid:sCjq/YtfokkxGYFCoHSo88BSXPM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31483	uniprotkb:Q8Z9R8	intact:EBI-1387216|uniprotkb:Q53SS9|uniprotkb:Q96B58|ensembl:ENSP00000401371.2	intact:EBI-2839934|uniprotkb:Q0W9Q7|intact:EBI-2857683|intact:EBI-2870000	psi-mi:tia1_human(display_long)|uniprotkb:TIA1(gene name)|psi-mi:TIA1(display_short)|uniprotkb:p40-TIA-1(gene name synonym)|uniprotkb:RNA-binding protein TIA-1(gene name synonym)|uniprotkb:T-cell-restricted intracellular antigen-1(gene name synonym)|uniprotkb:Nucleolysin TIA-1 isoform p40(gene name synonym)	psi-mi:mnmg_yerpe(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:YPO4130(locus name)|uniprotkb:y4144(locus name)|uniprotkb:YP_4037(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852606|imex:IM-13779-5692	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000116001.17(gene)|ensembl:ENST00000433529.7(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0006915""(apoptotic process)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0034063""(stress granule assembly)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0097165""(nuclear stress granule)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034496|interpro:IPR034827|interpro:IPR034830|interpro:IPR035979|mint:P31483|rcsb pdb:2MJN|rcsb pdb:3BS9|rcsb pdb:5ITH|rcsb pdb:5O2V|rcsb pdb:5O3J|rcsb pdb:6ELD|rcsb pdb:7VI4|rcsb pdb:7VI5|reactome:R-HSA-6803529|refseq:NP_071320.2|refseq:NP_071505.2|panther:PTHR10352(orthology-group)|efo:""Orphanet:603"""	"interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|interpro:IPR044920|interpro:IPR026904|refseq:WP_002212259.1|interpro:IPR049312|go:""GO:0002098""(tRNA wobble uridine modification)|go:""GO:0005829""(cytosol)|go:""GO:0030488""(tRNA methylation)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|interpro:IPR047001|refseq:YP_002348981.1|interpro:IPR040131|panther:PTHR11806(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:d2ecwJo5sjSY6a/By3GM3B5A6PE9606	rogid:v90IkqKm+dlosxfAPKVYWCflBG4632	intact-crc:6DD2B917686535EE|rigid:fhFHFXiHNs6GzF/MnwxHZWND4zc	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A5P8YGH4	uniprotkb:Q01085	intact:EBI-2842137|uniprotkb:Q0WF29|uniprotkb:Q7CIG0	intact:EBI-2820828|uniprotkb:A8K3T0|uniprotkb:A8K4L9|ensembl:ENSP00000394902.2	psi-mi:a0a5p8ygh4_yerpe(display_long)|uniprotkb:YPO2131(locus name)	psi-mi:tiar_human(display_long)|uniprotkb:TIAL1(gene name)|psi-mi:TIAL1(display_short)|uniprotkb:TIA-1-related protein(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852569|imex:IM-13779-5690	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR015406(Protein of unknown function DUF1983)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032876|refseq:WP_002211698.1|interpro:IPR036116|refseq:YP_002347109.1|interpro:IPR053171|panther:PTHR36251(orthology-group)	"refseq:NP_001029097.1|refseq:NP_003243.1|ensembl:ENSG00000151923.18(gene)|ensembl:ENST00000436547.7(transcript)|go:""GO:0003677""(DNA binding)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005764""(lysosome)|go:""GO:0005829""(cytosol)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0006915""(apoptotic process)|go:""GO:0006952""(defense response)|go:""GO:0007281""(germ cell development)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017145""(stem cell division)|go:""GO:0035332""(positive regulation of hippo signaling)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0044194""(cytolytic granule)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0140517""(protein-RNA adaptor activity)|go:""GO:2000637""(positive regulation of miRNA-mediated gene silencing)|go:""GO:2000648""(positive regulation of stem cell proliferation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034492|interpro:IPR034494|interpro:IPR034496|interpro:IPR035979|mint:Q01085|rcsb pdb:1X4G|rcsb pdb:2CQI|rcsb pdb:2DH7|reactome:R-HSA-6803529|dip:DIP-42425N|panther:PTHR10352(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:oOCFMN5J0JyZf3JZhYlAIr4sCxM632	rogid:dKWzIWmR/JaCJwsOLUPG2Z1uhH89606	intact-crc:7ECD0FE3D068E7A4|rigid:fLFdL9MfnRkfZX7hY9QVkLxe0u8	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8ZJJ5	uniprotkb:P31483	intact:EBI-2842956|uniprotkb:Q0WKJ3	intact:EBI-1387216|uniprotkb:Q53SS9|uniprotkb:Q96B58|ensembl:ENSP00000401371.2	psi-mi:hslu_yerpe(display_long)|uniprotkb:hslU(gene name)|psi-mi:hslU(display_short)|uniprotkb:Unfoldase HslU(gene name synonym)|uniprotkb:YPO0105(locus name)|uniprotkb:y0294(locus name)|uniprotkb:YP_0107(locus name)	psi-mi:tia1_human(display_long)|uniprotkb:TIA1(gene name)|psi-mi:TIA1(display_short)|uniprotkb:p40-TIA-1(gene name synonym)|uniprotkb:RNA-binding protein TIA-1(gene name synonym)|uniprotkb:T-cell-restricted intracellular antigen-1(gene name synonym)|uniprotkb:Nucleolysin TIA-1 isoform p40(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852599|imex:IM-13779-5693	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR004491(Heat shock protein HslU)|interpro:IPR027417|go:""GO:0008233""(peptidase activity)|go:""GO:0005524""(ATP binding)|go:""GO:0009376""(HslUV protease complex)|go:""GO:0016887""(ATP hydrolysis activity)|go:""GO:0036402""(proteasome-activating activity)|go:""GO:0043335""(protein unfolding)|go:""GO:0051603""(proteolysis involved in protein catabolic process)|refseq:WP_002208943.1|refseq:YP_002345195.1|interpro:IPR050052|panther:PTHR48102(orthology-group)"	"ensembl:ENSG00000116001.17(gene)|ensembl:ENST00000433529.7(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0006915""(apoptotic process)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0034063""(stress granule assembly)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0097165""(nuclear stress granule)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034496|interpro:IPR034827|interpro:IPR034830|interpro:IPR035979|mint:P31483|rcsb pdb:2MJN|rcsb pdb:3BS9|rcsb pdb:5ITH|rcsb pdb:5O2V|rcsb pdb:5O3J|rcsb pdb:6ELD|rcsb pdb:7VI4|rcsb pdb:7VI5|reactome:R-HSA-6803529|refseq:NP_071320.2|refseq:NP_071505.2|panther:PTHR10352(orthology-group)|efo:""Orphanet:603"""	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:9NL3dzNGgq2JqZd7+stwnNgbDk0632	rogid:d2ecwJo5sjSY6a/By3GM3B5A6PE9606	intact-crc:07A67A176BAAF6A0|rigid:YszbErxco6dX+toguxexBvbR/GE	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P31483	uniprotkb:Q8ZEH0	intact:EBI-1387216|uniprotkb:Q53SS9|uniprotkb:Q96B58|ensembl:ENSP00000401371.2	intact:EBI-2852576|uniprotkb:Q0WEW4	psi-mi:tia1_human(display_long)|uniprotkb:TIA1(gene name)|psi-mi:TIA1(display_short)|uniprotkb:p40-TIA-1(gene name synonym)|uniprotkb:RNA-binding protein TIA-1(gene name synonym)|uniprotkb:T-cell-restricted intracellular antigen-1(gene name synonym)|uniprotkb:Nucleolysin TIA-1 isoform p40(gene name synonym)	psi-mi:trpa_yerpe(display_long)|uniprotkb:trpA(gene name)|psi-mi:trpA(display_short)|uniprotkb:YPO2203(locus name)|uniprotkb:y2047(locus name)|uniprotkb:YP_2001(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852581|imex:IM-13779-5691	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000116001.17(gene)|ensembl:ENST00000433529.7(transcript)|go:""GO:0000381""(regulation of alternative mRNA splicing, via spliceosome)|go:""GO:0001818""(negative regulation of cytokine production)|go:""GO:0003723""(RNA binding)|go:""GO:0003730""(mRNA 3'-UTR binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0006915""(apoptotic process)|go:""GO:0008143""(""poly(A) binding"")|go:""GO:0008380""(RNA splicing)|go:""GO:0010494""(cytoplasmic stress granule)|go:""GO:0017148""(negative regulation of translation)|go:""GO:0034063""(stress granule assembly)|go:""GO:0035925""(mRNA 3'-UTR AU-rich region binding)|go:""GO:0048024""(regulation of mRNA splicing, via spliceosome)|go:""GO:0097165""(nuclear stress granule)|go:""GO:1903608""(protein localization to cytoplasmic stress granule)|go:""GO:1904037""(positive regulation of epithelial cell apoptotic process)|go:""GO:1990904""(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034496|interpro:IPR034827|interpro:IPR034830|interpro:IPR035979|mint:P31483|rcsb pdb:2MJN|rcsb pdb:3BS9|rcsb pdb:5ITH|rcsb pdb:5O2V|rcsb pdb:5O3J|rcsb pdb:6ELD|rcsb pdb:7VI4|rcsb pdb:7VI5|reactome:R-HSA-6803529|refseq:NP_071320.2|refseq:NP_071505.2|panther:PTHR10352(orthology-group)|efo:""Orphanet:603"""	"interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR018204|interpro:IPR002028(Tryptophan synthase, alpha chain)|refseq:WP_002210634.1|go:""GO:0000162""(L-tryptophan biosynthetic process)|go:""GO:0004834""(tryptophan synthase activity)|go:""GO:0005829""(cytosol)|go:""GO:0006568""(L-tryptophan metabolic process)|refseq:YP_002347174.1|panther:PTHR43406(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:d2ecwJo5sjSY6a/By3GM3B5A6PE9606	rogid:YRspPhrujWjFq0fO28SvlvSJrIE632	intact-crc:6CBDA5176A854EB3|rigid:y/BiEJ6vBPfzf533KA+fHrSrk3c	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2GYU0	uniprotkb:Q9NS62	intact:EBI-2847562|uniprotkb:A0A380PDR3|uniprotkb:Q0WFV2|uniprotkb:Q7CI00|uniprotkb:A0A384KNN0	intact:EBI-2852613|uniprotkb:B2RCF5|uniprotkb:A2A3J3|uniprotkb:Q6UXZ2|uniprotkb:Q6P3U1|ensembl:ENSP00000258613.4	psi-mi:a0a2u2gyu0_yerpe(display_long)|uniprotkb:flaF(gene name)|psi-mi:flaF(display_short)|uniprotkb:fliC(gene name synonym)|uniprotkb:hag(gene name synonym)|uniprotkb:YPO1842(locus name)	psi-mi:thsd1_human(display_long)|uniprotkb:THSD1(gene name)|psi-mi:THSD1(display_short)|uniprotkb:TMTSP(gene name synonym)|uniprotkb:Transmembrane molecule with thrombospondin module(gene name synonym)|uniprotkb:UNQ3010/PRO9769(orf name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852621|imex:IM-13779-5695	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR042187|refseq:WP_002211152.1|go:""GO:0005198""(structural molecule activity)|go:""GO:0005576""(extracellular region)|go:""GO:0009288""(bacterial-type flagellum)|refseq:YP_002346836.1|interpro:IPR046358"	"efo:""Orphanet:231160""|efo:""Orphanet:363999""|ensembl:ENSG00000136114.17(gene)|ensembl:ENST00000258613.5(transcript)|go:""GO:0005576""(extracellular region)|go:""GO:0005768""(endosome)|go:""GO:0005829""(cytosol)|go:""GO:0005925""(focal adhesion)|go:""GO:0010008""(endosome membrane)|go:""GO:0048041""(focal adhesion assembly)|go:""GO:0050840""(extracellular matrix binding)|go:""GO:0071944""(cell periphery)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR036383|interpro:IPR038877|reactome:R-HSA-5083635|reactome:R-HSA-5173214|refseq:NP_061146.1|refseq:NP_954872.1|panther:PTHR16311(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:0iQC5KNYj/iy3Dwyc0YTHeiyqhs632	rogid:g7tfrqrc5wkaPv0zj9GrZAITrCs9606	intact-crc:45362781323D92DA|rigid:6JbGBQdb5MtK9EjNLuOe7YrMI1Y	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P01137	uniprotkb:Q8ZIL4	intact:EBI-779636|uniprotkb:Q9UCG4|uniprotkb:A8K792|ensembl:ENSP00000221930.4	intact:EBI-2852663|uniprotkb:Q0WJI3	psi-mi:tgfb1_human(display_long)|uniprotkb:TGFB1(gene name)|psi-mi:TGFB1(display_short)|uniprotkb:TGFB(gene name synonym)	psi-mi:carb_yerpe(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:Carbamoyl phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:YPO0482(locus name)|uniprotkb:YP_3697(locus name)|uniprotkb:y3692(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852669|imex:IM-13779-5697	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"dip:DIP-5934N|ensembl:ENSG00000105329.11(gene)|ensembl:ENST00000221930.6(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000902""(cell morphogenesis)|go:""GO:0001570""(vasculogenesis)|go:""GO:0001657""(ureteric bud development)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001843""(neural tube closure)|go:""GO:0002028""(regulation of sodium ion transport)|go:""GO:0002040""(sprouting angiogenesis)|go:""GO:0002062""(chondrocyte differentiation)|go:""GO:0002069""(columnar/cuboidal epithelial cell maturation)|go:""GO:0002244""(hematopoietic progenitor cell differentiation)|go:""GO:0002248""(connective tissue replacement involved in inflammatory response wound healing)|go:""GO:0002460""(adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains)|go:""GO:0002513""(tolerance induction to self antigen)|go:""GO:0002859""(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:""GO:0003179""(heart valve morphogenesis)|go:""GO:0003180""(aortic valve morphogenesis)|go:""GO:0005114""(type II transforming growth factor beta receptor binding)|go:""GO:0005125""(cytokine activity)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005634""(nucleus)|go:""GO:0005737""(cytoplasm)|go:""GO:0005796""(Golgi lumen)|go:""GO:0005886""(plasma membrane)|go:""GO:0006611""(protein export from nucleus)|go:""GO:0006754""(ATP biosynthetic process)|go:""GO:0006796""(phosphate-containing compound metabolic process)|go:""GO:0006874""(intracellular calcium ion homeostasis)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007219""(Notch signaling pathway)|go:""GO:0007406""(negative regulation of neuroblast proliferation)|go:""GO:0007435""(salivary gland morphogenesis)|go:""GO:0007492""(endoderm development)|go:""GO:0007507""(heart development)|go:""GO:0007565""(female pregnancy)|go:""GO:0008083""(growth factor activity)|go:""GO:0008284""(positive regulation of cell population proliferation)|go:""GO:0008285""(negative regulation of cell population proliferation)|go:""GO:0008354""(germ cell migration)|go:""GO:0009410""(response to xenobiotic stimulus)|go:""GO:0009611""(response to wounding)|go:""GO:0009986""(cell surface)|go:""GO:0010467""(gene expression)|go:""GO:0010575""(positive regulation of vascular endothelial growth factor production)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0010629""(negative regulation of gene expression)|go:""GO:0010716""(negative regulation of extracellular matrix disassembly)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010742""(macrophage derived foam cell differentiation)|go:""GO:0010763""(positive regulation of fibroblast migration)|go:""GO:0010936""(negative regulation of macrophage cytokine production)|go:""GO:0014003""(oligodendrocyte development)|go:""GO:0014008""(positive regulation of microglia differentiation)|go:""GO:0016202""(regulation of striated muscle tissue development)|go:""GO:0019899""(enzyme binding)|go:""GO:0021915""(neural tube development)|go:""GO:0030214""(hyaluronan catabolic process)|go:""GO:0030279""(negative regulation of ossification)|go:""GO:0030308""(negative regulation of cell growth)|go:""GO:0030316""(osteoclast differentiation)|go:""GO:0030334""(regulation of cell migration)|go:""GO:0030335""(positive regulation of cell migration)|go:""GO:0030424""(axon)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031093""(platelet alpha granule lumen)|go:""GO:0031293""(membrane protein intracellular domain proteolysis)|go:""GO:0031334""(positive regulation of protein-containing complex assembly)|go:""GO:0031536""(positive regulation of exit from mitosis)|go:""GO:0032355""(response to estradiol)|go:""GO:0032570""(response to progesterone)|go:""GO:0032667""(regulation of interleukin-23 production)|go:""GO:0032700""(negative regulation of interleukin-17 production)|go:""GO:0032740""(positive regulation of interleukin-17 production)|go:""GO:0032755""(positive regulation of interleukin-6 production)|go:""GO:0032760""(positive regulation of tumor necrosis factor production)|go:""GO:0032801""(receptor catabolic process)|go:""GO:0032930""(positive regulation of superoxide anion generation)|go:""GO:0032956""(regulation of actin cytoskeleton organization)|go:""GO:0032967""(positive regulation of collagen biosynthetic process)|go:""GO:0033280""(response to vitamin D)|go:""GO:0034616""(response to laminar fluid shear stress)|go:""GO:0034713""(type I transforming growth factor beta receptor binding)|go:""GO:0034714""(type III transforming growth factor beta receptor binding)|go:""GO:0035800""(deubiquitinase activator activity)|go:""GO:0035902""(response to immobilization stress)|go:""GO:0036446""(myofibroblast differentiation)|go:""GO:0042098""(T cell proliferation)|go:""GO:0042127""(regulation of cell population proliferation)|go:""GO:0042130""(negative regulation of T cell proliferation)|go:""GO:0042306""(regulation of protein import into nucleus)|go:""GO:0042307""(positive regulation of protein import into nucleus)|go:""GO:0042475""(odontogenesis of dentin-containing tooth)|go:""GO:0042482""(positive regulation of odontogenesis)|go:""GO:0042552""(myelination)|go:""GO:0042802""(identical protein binding)|go:""GO:0043025""(neuronal cell body)|go:""GO:0043029""(T cell homeostasis)|go:""GO:0043117""(positive regulation of vascular permeability)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043129""(surfactant homeostasis)|go:""GO:0043410""(positive regulation of MAPK cascade)|go:""GO:0043536""(positive regulation of blood vessel endothelial cell migration)|go:""GO:0043537""(negative regulation of blood vessel endothelial cell migration)|go:""GO:0043539""(protein serine/threonine kinase activator activity)|go:""GO:0044877""(protein-containing complex binding)|go:""GO:0045066""(regulatory T cell differentiation)|go:""GO:0045216""(cell-cell junction organization)|go:""GO:0045591""(positive regulation of regulatory T cell differentiation)|go:""GO:0045596""(negative regulation of cell differentiation)|go:""GO:0045599""(negative regulation of fat cell differentiation)|go:""GO:0045662""(negative regulation of myoblast differentiation)|go:""GO:0045742""(positive regulation of epidermal growth factor receptor signaling pathway)|go:""GO:0045786""(negative regulation of cell cycle)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045893""(positive regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0046716""(muscle cell cellular homeostasis)|go:""GO:0048146""(positive regulation of fibroblast proliferation)|go:""GO:0048286""(lung alveolus development)|go:""GO:0048298""(positive regulation of isotype switching to IgA isotypes)|go:""GO:0048535""(lymph node development)|go:""GO:0048565""(digestive tract development)|go:""GO:0048642""(negative regulation of skeletal muscle tissue development)|go:""GO:0048661""(positive regulation of smooth muscle cell proliferation)|go:""GO:0048839""(inner ear development)|go:""GO:0050673""(epithelial cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0050714""(positive regulation of protein secretion)|go:""GO:0050729""(positive regulation of inflammatory response)|go:""GO:0050731""(positive regulation of peptidyl-tyrosine phosphorylation)|go:""GO:0050765""(negative regulation of phagocytosis)|go:""GO:0050832""(defense response to fungus)|go:""GO:0050921""(positive regulation of chemotaxis)|go:""GO:0051152""(positive regulation of smooth muscle cell differentiation)|go:""GO:0051247""(positive regulation of protein metabolic process)|go:""GO:0051280""(negative regulation of release of sequestered calcium ion into cytosol)|go:""GO:0051402""(neuron apoptotic process)|go:""GO:0051781""(positive regulation of cell division)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0055010""(ventricular cardiac muscle tissue morphogenesis)|go:""GO:0055091""(phospholipid homeostasis)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0060312""(regulation of blood vessel remodeling)|go:""GO:0060325""(face morphogenesis)|go:""GO:0060364""(frontal suture morphogenesis)|go:""GO:0060391""(positive regulation of SMAD protein signal transduction)|go:""GO:0060435""(bronchiole development)|go:""GO:0060744""(mammary gland branching involved in thelarche)|go:""GO:0060751""(branch elongation involved in mammary gland duct branching)|go:""GO:0060762""(regulation of branching involved in mammary gland duct morphogenesis)|go:""GO:0061035""(regulation of cartilage development)|go:""GO:0061298""(retina vasculature development in camera-type eye)|go:""GO:0061520""(Langerhans cell differentiation)|go:""GO:0062023""(collagen-containing extracellular matrix)|go:""GO:0070168""(negative regulation of biomineral tissue development)|go:""GO:0070173""(regulation of enamel mineralization)|go:""GO:0070306""(lens fiber cell differentiation)|go:""GO:0070374""(positive regulation of ERK1 and ERK2 cascade)|go:""GO:0070723""(response to cholesterol)|go:""GO:0071260""(cellular response to mechanical stimulus)|go:""GO:0071333""(cellular response to glucose stimulus)|go:""GO:0071404""(cellular response to low-density lipoprotein particle stimulus)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:0071479""(cellular response to ionizing radiation)|go:""GO:0071549""(cellular response to dexamethasone stimulus)|go:""GO:0071560""(cellular response to transforming growth factor beta stimulus)|go:""GO:0071677""(positive regulation of mononuclear cell migration)|go:""GO:0071895""(odontoblast differentiation)|go:""GO:0072089""(stem cell proliferation)|go:""GO:0072562""(blood microparticle)|go:""GO:0085029""(extracellular matrix assembly)|go:""GO:0090190""(positive regulation of branching involved in ureteric bud morphogenesis)|go:""GO:0090263""(positive regulation of canonical Wnt signaling pathway)|go:""GO:0097191""(extrinsic apoptotic signaling pathway)|go:""GO:0097421""(liver regeneration)|go:""GO:0098586""(cellular response to virus)|go:""GO:1900126""(negative regulation of hyaluronan biosynthetic process)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1901203""(positive regulation of extracellular matrix assembly)|go:""GO:1902074""(response to salt)|go:""GO:1902462""(positive regulation of mesenchymal stem cell proliferation)|go:""GO:1902894""(negative regulation of miRNA transcription)|go:""GO:1902895""(positive regulation of miRNA transcription)|go:""GO:1903077""(negative regulation of protein localization to plasma membrane)|go:""GO:1904018""(positive regulation of vasculature development)|go:""GO:1904894""(positive regulation of receptor signaling pathway via STAT)|go:""GO:1905641""(cellular response to acetaldehyde)|go:""GO:1990314""(cellular response to insulin-like growth factor stimulus)|go:""GO:1990402""(embryonic liver development)|go:""GO:2000048""(negative regulation of cell-cell adhesion mediated by cadherin)|go:""GO:2000343""(""positive regulation of chemokine (C-X-C motif) ligand 2 production"")|go:""GO:2000353""(positive regulation of endothelial cell apoptotic process)|go:""GO:2000636""(positive regulation of primary miRNA processing)|go:""GO:2000727""(positive regulation of cardiac muscle cell differentiation)|interpro:IPR001111(""Transforming growth factor beta (TGFb), N-terminal"")|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR003939(Transforming growth factor, beta 1)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR016319(Transforming growth factor-beta)|interpro:IPR017948|interpro:IPR029034|mint:P01137|rcsb pdb:1KLA|rcsb pdb:1KLC|rcsb pdb:1KLD|rcsb pdb:3KFD|rcsb pdb:4KV5|rcsb pdb:5FFO|rcsb pdb:5VQP|rcsb pdb:6OM2|rcsb pdb:6P7J|rcsb pdb:7Y1R|rcsb pdb:7Y1T|rcsb pdb:8UDZ|rcsb pdb:8VSC|reactome:R-HSA-114608|reactome:R-HSA-168277|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-3304356|reactome:R-HSA-3642279|reactome:R-HSA-3645790|reactome:R-HSA-3656532|reactome:R-HSA-3656535|reactome:R-HSA-381340|reactome:R-HSA-5689603|reactome:R-HSA-6785807|reactome:R-HSA-8941855|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9839389|refseq:NP_000651.3|efo:""Orphanet:1328""|efo:""Orphanet:565788""|efo:""Orphanet:586""|panther:PTHR11848(orthology-group)"	"interpro:IPR011761(ATP-grasp fold)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR011607(MGS-like)|interpro:IPR016185(PreATP-grasp-like fold)|refseq:WP_002210502.1|go:""GO:0004087""(""carbamoyl-phosphate synthase (ammonia) activity"")|go:""GO:0004088""(""carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"")|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006526""(L-arginine biosynthetic process)|go:""GO:0006541""(glutamine metabolic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046872""(metal ion binding)|interpro:IPR033937|interpro:IPR036897|interpro:IPR036914|refseq:YP_002345555.1|panther:PTHR11405(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/01/23	rogid:ZWezT0bctf1h6Z0Ga0z9faNoMmM9606	rogid:l/RzabCD1P/dEo/AmaYoXpYV1FY632	intact-crc:AF5FFC9F2D9F6842|rigid:Mw7h8PeldikpMl7Nxo5xA7i4pUw	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:P42765	uniprotkb:A0A2U2GYT1	intact:EBI-2852639|uniprotkb:Q9BUT6|ensembl:ENSP00000285093.8	intact:EBI-2850019|uniprotkb:Q74UX9|uniprotkb:A0A5P8YEY5|uniprotkb:A0A0H2W327|uniprotkb:Q7CHZ4|uniprotkb:A0A384L0J7	psi-mi:thim_human(display_long)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:ACAA2(gene name)|psi-mi:ACAA2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:T1(gene name synonym)	psi-mi:a0a2u2gyt1_yerpe(display_long)|uniprotkb:fla AII.2(gene name)|psi-mi:fla AII.2(display_short)|uniprotkb:fla BII(gene name synonym)|uniprotkb:fliG(gene name synonym)|uniprotkb:YPO1829(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852644|imex:IM-13779-5699	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_006102.2|ensembl:ENSG00000167315.18(gene)|ensembl:ENST00000285093.15(transcript)|go:""GO:0003723""(RNA binding)|go:""GO:0003985""(acetyl-CoA C-acetyltransferase activity)|go:""GO:0003986""(acetyl-CoA hydrolase activity)|go:""GO:0003988""(acetyl-CoA C-acyltransferase activity)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0006635""(fatty acid beta-oxidation)|go:""GO:0006695""(cholesterol biosynthetic process)|go:""GO:0047617""(fatty acyl-CoA hydrolase activity)|go:""GO:0071456""(cellular response to hypoxia)|go:""GO:1901029""(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:""GO:1902109""(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P42765|rcsb pdb:4C2J|rcsb pdb:4C2K|reactome:R-HSA-77289|panther:PTHR18919(orthology-group)"	"interpro:IPR023087|interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR028263|refseq:WP_002211142.1|go:""GO:0003774""(cytoskeletal motor activity)|go:""GO:0005886""(plasma membrane)|go:""GO:0006935""(chemotaxis)|go:""GO:0009425""(bacterial-type flagellum basal body)|go:""GO:0071973""(bacterial-type flagellum-dependent cell motility)|refseq:YP_002346825.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/01	rogid:TJMFLcEB5eKz36plSuUiteAJN9g9606	rogid:YBRmcuS18DJP2sfWEnw15dGyeYk632	intact-crc:7DBE96E3CAA3EB49|rigid:qQQxBZiYojENiCL122gIwpAlTfQ	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2U2H0K6	uniprotkb:Q86V81	intact:EBI-2852628|uniprotkb:A0A3N4B3P8|uniprotkb:Q0WDD4|uniprotkb:Q7CJB1|uniprotkb:A0A384KN94	intact:EBI-347640|uniprotkb:O43672	psi-mi:a0a2u2h0k6_yerpe(display_long)|uniprotkb:fabB(gene name)|psi-mi:fabB(display_short)|uniprotkb:fabC(gene name synonym)|uniprotkb:YPO2757(locus name)|uniprotkb:3-oxoacyl-[acyl-carrier-protein] synthase I(gene name synonym)|uniprotkb:Beta-ketoacyl-ACP synthase I(gene name synonym)	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852632|imex:IM-13779-5696	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR018201|rcsb pdb:3OYT|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016039(Thiolase-like)|refseq:WP_002209717.1|interpro:IPR020841|go:""GO:0004315""(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006633""(fatty acid biosynthetic process)|interpro:IPR000794(Beta-ketoacyl synthase)|refseq:YP_002347704.1"	"go:""GO:0000346""(transcription export complex)|go:""GO:0001649""(osteoblast differentiation)|go:""GO:0003723""(RNA binding)|go:""GO:0003729""(mRNA binding)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006397""(mRNA processing)|go:""GO:0006405""(RNA export from nucleus)|go:""GO:0006406""(mRNA export from nucleus)|go:""GO:0008380""(RNA splicing)|go:""GO:0016020""(membrane)|go:""GO:0016607""(nuclear speck)|go:""GO:0062153""(C5-methylcytidine-containing RNA reader activity)|go:""GO:0070062""(extracellular exosome)|go:""GO:0071013""(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR025715|interpro:IPR035979|interpro:IPR051229|rcsb pdb:3ULH|rcsb pdb:7ZNJ|rcsb pdb:7ZNK|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|panther:PTHR19965(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/03/27	rogid:+3E+vKvbzG7y9HxBalF+akckeKw632	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	intact-crc:293A646521629347|rigid:uUgV+1jnBP8aJLlOuWbuILzotgU	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NPJ3	uniprotkb:A0A5P8YCM5	intact:EBI-1045357|uniprotkb:O95549|uniprotkb:F5H2L4|ensembl:ENSP00000230048.3	intact:EBI-2852654|uniprotkb:Q74XV6|uniprotkb:Q0WBM9|uniprotkb:Q7CKE4|uniprotkb:A0A384K8A4	psi-mi:aco13_human(display_long)|uniprotkb:ACOT13(gene name)|psi-mi:ACOT13(display_short)|uniprotkb:HT012(orf name)|uniprotkb:PNAS-27(orf name)|uniprotkb:THEM2(gene name synonym)|uniprotkb:Thioesterase superfamily member 2(gene name synonym)|uniprotkb:Hotdog-fold thioesterase superfamily member 2(gene name synonym)|uniprotkb:Palmitoyl-CoA hydrolase(gene name synonym)	psi-mi:a0a5p8ycm5_yerpe(display_long)|uniprotkb:lpdA(gene name synonym)|uniprotkb:lpd(gene name)|psi-mi:lpd(display_short)|uniprotkb:YPO3417(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852651|imex:IM-13779-5698	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001153566.1|refseq:NP_060943.1|ensembl:ENSG00000112304.11(gene)|ensembl:ENST00000230048.5(transcript)|go:""GO:0005634""(nucleus)|go:""GO:0005739""(mitochondrion)|go:""GO:0005759""(mitochondrial matrix)|go:""GO:0005819""(spindle)|go:""GO:0005829""(cytosol)|go:""GO:0006629""(lipid metabolic process)|go:""GO:0046872""(metal ion binding)|go:""GO:0047617""(fatty acyl-CoA hydrolase activity)|go:""GO:0051289""(protein homotetramerization)|go:""GO:0120163""(negative regulation of cold-induced thermogenesis)|interpro:IPR003736(Phenylacetic acid degradation-related protein)|interpro:IPR006683(Thioesterase superfamily)|interpro:IPR029069|interpro:IPR039298|rcsb pdb:2F0X|rcsb pdb:2H4U|rcsb pdb:3F5O|reactome:R-HSA-77289|panther:PTHR21660(orthology-group)"	"interpro:IPR050151|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|go:""GO:0004148""(""dihydrolipoyl dehydrogenase (NADH) activity"")|go:""GO:0006090""(pyruvate metabolic process)|go:""GO:0006103""(2-oxoglutarate metabolic process)|go:""GO:0050660""(flavin adenine dinucleotide binding)|interpro:IPR036188|refseq:YP_002348309.1|panther:PTHR22912(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:1PIdQF7TRL5b+kl/7M+pVh4JH0I9606	rogid:Go+VQYI1pG0P840+rizw8ZRDsHc632	intact-crc:0B258E00934F38AF|rigid:xYT7d4GMaytPjTi6/a/TKJ48QPk	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q8CLD5	uniprotkb:Q9NQB0	intact:EBI-2841300	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274.4	psi-mi:q8cld5_yerpe(display_long)|uniprotkb:y1556(locus name)	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852706|imex:IM-13779-5703	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"go:""GO:0016020""(membrane)"	"ensembl:ENSG00000148737.18(gene)|ensembl:ENST00000355995.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001568""(blood vessel development)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009749""(response to glucose)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010909""(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016605""(PML body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031016""(pancreas development)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032350""(regulation of hormone metabolic process)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0043570""(maintenance of DNA repeat elements)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045721""(negative regulation of gluconeogenesis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048625""(myoblast fate commitment)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070369""(beta-catenin-TCF7L2 complex)|go:""GO:0071664""(catenin-TCF7L2 complex)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990907""(beta-catenin-TCF complex)|go:""GO:2000675""(negative regulation of type B pancreatic cell apoptotic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430|reactome:R-HSA-9823730|reactome:R-HSA-9825892|refseq:NP_001139746.1|refseq:NP_001139755.1|refseq:NP_001139756.1|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270141.1|refseq:XP_005270146.1|refseq:XP_005270153.1|refseq:XP_005270160.1|refseq:XP_016872081.1|refseq:XP_016872082.1|efo:""Orphanet:528084""|dip:DIP-36236N|ensembl:ENST00000352065.10|ensembl:ENSP00000344823.5|ensembl:ENST00000355717.9|ensembl:ENSP00000347949.4|ensembl:ENSP00000348274.4|ensembl:ENST00000369397.8|ensembl:ENSP00000358404.4|ensembl:ENST00000538897.5|ensembl:ENSP00000446172.1|ensembl:ENST00000627217.3|ensembl:ENSP00000486891.1|panther:PTHR10373(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:hmpi8VS21Gwnqp0z5+9hqOek7AQ632	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	intact-crc:9000E34F32EBF963|rigid:zoVMevpTOVRKiSXTtIZdN9XGSwM	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A384KHP8	uniprotkb:Q03167	intact:EBI-2840740|uniprotkb:Q74S58|uniprotkb:Q0WHX7|uniprotkb:Q7CH24	intact:EBI-2852679|uniprotkb:Q5T2T4|uniprotkb:B9EG88|uniprotkb:Q9UGI2|uniprotkb:A0AUW8|uniprotkb:Q5U731|uniprotkb:A8K5N0|ensembl:ENSP00000212355.4|ensembl:ENSP00000436127.1	psi-mi:a0a384khp8_yerpe(display_long)|uniprotkb:cutF(gene name)|psi-mi:cutF(display_short)|uniprotkb:nlpE(gene name synonym)|uniprotkb:YPO1067(locus name)	psi-mi:tgbr3_human(display_long)|uniprotkb:TGFBR3(gene name)|psi-mi:TGFBR3(display_short)|uniprotkb:Betaglycan(gene name synonym)|uniprotkb:Transforming growth factor beta receptor III(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852676|imex:IM-13779-5700	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	interpro:IPR007298(Copper resistance lipoprotein NlpE)|interpro:IPR033450|interpro:IPR038139|interpro:IPR043176|refseq:YP_002346111.1	"efo:""Orphanet:231160""|dip:DIP-5940N|ensembl:ENSG00000069702.11(gene)|ensembl:ENST00000212355.9(transcript)|ensembl:ENST00000525962.5(transcript)|go:""GO:0001666""(response to hypoxia)|go:""GO:0001837""(epithelial to mesenchymal transition)|go:""GO:0001889""(liver development)|go:""GO:0003007""(heart morphogenesis)|go:""GO:0003150""(muscular septum morphogenesis)|go:""GO:0003151""(outflow tract morphogenesis)|go:""GO:0003223""(ventricular compact myocardium morphogenesis)|go:""GO:0004888""(transmembrane signaling receptor activity)|go:""GO:0005024""(transforming growth factor beta receptor activity)|go:""GO:0005114""(type II transforming growth factor beta receptor binding)|go:""GO:0005160""(transforming growth factor beta receptor binding)|go:""GO:0005539""(glycosaminoglycan binding)|go:""GO:0005576""(extracellular region)|go:""GO:0005615""(extracellular space)|go:""GO:0005829""(cytosol)|go:""GO:0005886""(plasma membrane)|go:""GO:0006955""(immune response)|go:""GO:0007179""(transforming growth factor beta receptor signaling pathway)|go:""GO:0007181""(transforming growth factor beta receptor complex assembly)|go:""GO:0008201""(heparin binding)|go:""GO:0009897""(external side of plasma membrane)|go:""GO:0009986""(cell surface)|go:""GO:0010628""(positive regulation of gene expression)|go:""GO:0015026""(coreceptor activity)|go:""GO:0016323""(basolateral plasma membrane)|go:""GO:0016477""(cell migration)|go:""GO:0017015""(regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0017134""(fibroblast growth factor binding)|go:""GO:0030165""(PDZ domain binding)|go:""GO:0030336""(negative regulation of cell migration)|go:""GO:0030509""(BMP signaling pathway)|go:""GO:0030511""(positive regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0030512""(negative regulation of transforming growth factor beta receptor signaling pathway)|go:""GO:0031100""(animal organ regeneration)|go:""GO:0032354""(response to follicle-stimulating hormone)|go:""GO:0034673""(inhibin-betaglycan-ActRII complex)|go:""GO:0034695""(response to prostaglandin E)|go:""GO:0034699""(response to luteinizing hormone)|go:""GO:0035556""(intracellular signal transduction)|go:""GO:0036122""(BMP binding)|go:""GO:0043124""(negative regulation of canonical NF-kappaB signal transduction)|go:""GO:0043235""(receptor complex)|go:""GO:0046332""(SMAD binding)|go:""GO:0048185""(activin binding)|go:""GO:0050431""(transforming growth factor beta binding)|go:""GO:0050680""(negative regulation of epithelial cell proliferation)|go:""GO:0055010""(ventricular cardiac muscle tissue morphogenesis)|go:""GO:0060038""(cardiac muscle cell proliferation)|go:""GO:0060045""(positive regulation of cardiac muscle cell proliferation)|go:""GO:0060216""(definitive hemopoiesis)|go:""GO:0060317""(cardiac epithelial to mesenchymal transition)|go:""GO:0060318""(definitive erythrocyte differentiation)|go:""GO:0060347""(heart trabecula formation)|go:""GO:0060391""(positive regulation of SMAD protein signal transduction)|go:""GO:0060392""(negative regulation of SMAD protein signal transduction)|go:""GO:0060412""(ventricular septum morphogenesis)|go:""GO:0060939""(epicardium-derived cardiac fibroblast cell development)|go:""GO:0060979""(vasculogenesis involved in coronary vascular morphogenesis)|go:""GO:0061384""(heart trabecula morphogenesis)|go:""GO:0062009""(secondary palate development)|go:""GO:0070062""(extracellular exosome)|go:""GO:0070123""(transforming growth factor beta receptor activity, type III)|go:""GO:0090050""(positive regulation of cell migration involved in sprouting angiogenesis)|go:""GO:1901202""(negative regulation of extracellular matrix assembly)|interpro:IPR001507(Endoglin/CD105 antigen)|interpro:IPR017977|interpro:IPR042235|interpro:IPR048290|mint:Q03167|rcsb pdb:7LBG|reactome:R-HSA-1502540|reactome:R-HSA-190370|reactome:R-HSA-190373|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-9839383|reactome:R-HSA-9839389|reactome:R-HSA-9839394|reactome:R-HSA-9839397|reactome:R-HSA-9839406|refseq:NP_001182612.1|refseq:NP_001182613.1|refseq:NP_003234.2|refseq:XP_006710930.1|refseq:XP_006710931.1|panther:PTHR14002(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:ryLPtdXQoNwxiqxUzYaySoAkJkc632	rogid:kuGStoHrPMovTMQ/iCz6NhHOJ4k9606	intact-crc:D45F72E6F43CA7EC|rigid:R7XdZ9p7gPrlLR0q6jy8D4SGmBs	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q92734	uniprotkb:Q8D1J9	intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|intact:EBI-28969365|uniprotkb:G5E9V1|ensembl:ENSP00000240851.4|ensembl:ENSP00000419960.1|ensembl:ENSP00000420797.2|ensembl:ENSP00000501815.1|ensembl:ENSP00000502071.1|ensembl:ENSP00000502450.1|ensembl:ENSP00000502592.1|ensembl:ENSP00000502734.1|uniprotkb:K0J5S8|uniprotkb:K0J6K2	intact:EBI-2844009|uniprotkb:Q74R75	psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym)	psi-mi:q8d1j9_yerpe(display_long)|uniprotkb:uvrD(gene name)|psi-mi:uvrD(display_short)|uniprotkb:DNA 3'-5' helicase II(gene name synonym)|uniprotkb:YP_3206(locus name)|uniprotkb:y0389(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852699|imex:IM-13779-5704	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"efo:""Orphanet:146""|efo:""Orphanet:209916""|efo:""Orphanet:431329""|efo:""Orphanet:435819""|efo:""Orphanet:90117""|ensembl:ENSG00000114354.15(gene)|ensembl:ENST00000240851.9(transcript)|ensembl:ENST00000487505.6(transcript)|ensembl:ENST00000490574.6(transcript)|ensembl:ENST00000674615.1(transcript)|ensembl:ENST00000675243.1(transcript)|ensembl:ENST00000675499.1(transcript)|ensembl:ENST00000675553.1(transcript)|ensembl:ENST00000676395.1(transcript)|go:""GO:0005737""(cytoplasm)|go:""GO:0005829""(cytosol)|go:""GO:0006888""(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:""GO:0042802""(identical protein binding)|go:""GO:0043123""(positive regulation of canonical NF-kappaB signal transduction)|go:""GO:0043231""(intracellular membrane-bounded organelle)|go:""GO:0048208""(COPII vesicle coating)|go:""GO:0070971""(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|interpro:IPR053793|mint:Q92734|rcsb pdb:8TEQ|rcsb pdb:8TER|reactome:R-HSA-204005|reactome:R-HSA-9725370|refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|refseq:XP_005247123.1|refseq:XP_006713535.1|refseq:XP_006713536.1|refseq:XP_011510636.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1|panther:PTHR15335(orthology-group)"	"interpro:IPR005753(DNA helicase, ATP-dependent, UvrD type)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR027417|go:""GO:0003677""(DNA binding)|go:""GO:0005524""(ATP binding)|go:""GO:0005737""(cytoplasm)|go:""GO:0006268""(obsolete DNA unwinding involved in DNA replication)|go:""GO:0009378""(four-way junction helicase activity)|go:""GO:0016787""(hydrolase activity)|go:""GO:0016853""(isomerase activity)|go:""GO:0036121""(double-stranded DNA helicase activity)|go:""GO:0061749""(forked DNA-dependent helicase activity)|go:""GO:1990518""(single-stranded 3'-5' DNA helicase activity)|interpro:IPR013986(DNA helicase, DEXX box type)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606	rogid:PolYsqnEbJnfKp6krRc+FLB+mdg632	intact-crc:DD72A0D249FDB8B5|rigid:2O2/MyILSBzJVfb9Kitzaq4Im1g	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:A0A2S9PJM4	uniprotkb:Q9NQB0	intact:EBI-2845974|uniprotkb:Q74XF1|uniprotkb:Q7CKP1|uniprotkb:A0A3N4B1T8|uniprotkb:A0A0H2W2H9	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274.4	psi-mi:a0a2s9pjm4_yerpe(display_long)|uniprotkb:tyrB(gene name)|psi-mi:tyrB(display_short)|uniprotkb:YPO0322(locus name)	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852713|imex:IM-13779-5702	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|refseq:WP_002209097.1|go:""GO:0006520""(amino acid metabolic process)|go:""GO:0008483""(transaminase activity)|go:""GO:0009058""(biosynthetic process)|go:""GO:0030170""(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:YP_002345402.1"	"ensembl:ENSG00000148737.18(gene)|ensembl:ENST00000355995.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001568""(blood vessel development)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009749""(response to glucose)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010909""(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016605""(PML body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031016""(pancreas development)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032350""(regulation of hormone metabolic process)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0043570""(maintenance of DNA repeat elements)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045721""(negative regulation of gluconeogenesis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048625""(myoblast fate commitment)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070369""(beta-catenin-TCF7L2 complex)|go:""GO:0071664""(catenin-TCF7L2 complex)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990907""(beta-catenin-TCF complex)|go:""GO:2000675""(negative regulation of type B pancreatic cell apoptotic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430|reactome:R-HSA-9823730|reactome:R-HSA-9825892|refseq:NP_001139746.1|refseq:NP_001139755.1|refseq:NP_001139756.1|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270141.1|refseq:XP_005270146.1|refseq:XP_005270153.1|refseq:XP_005270160.1|refseq:XP_016872081.1|refseq:XP_016872082.1|efo:""Orphanet:528084""|dip:DIP-36236N|ensembl:ENST00000352065.10|ensembl:ENSP00000344823.5|ensembl:ENST00000355717.9|ensembl:ENSP00000347949.4|ensembl:ENSP00000348274.4|ensembl:ENST00000369397.8|ensembl:ENSP00000358404.4|ensembl:ENST00000538897.5|ensembl:ENSP00000446172.1|ensembl:ENST00000627217.3|ensembl:ENSP00000486891.1|panther:PTHR10373(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:gUXDGn5QEZOQcHwUvev80Fg2l8s632	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	intact-crc:7BF0761467D23C6E|rigid:BeumIohnYCzFVQH6urkarwGivrg	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9UBB9	uniprotkb:A0A0H2W225	intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|uniprotkb:Q20WL0|ensembl:ENSP00000383892.1|ensembl:ENSP00000384297.1|ensembl:ENSP00000384421.1|ensembl:ENSP00000385861.1|ensembl:ENSP00000480171.1	intact:EBI-2844774	psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym)	psi-mi:a0a0h2w225_yerpe(display_long)|uniprotkb:sbcC2(gene name)|psi-mi:sbcC2(display_short)|uniprotkb:sbcC(gene name synonym)|uniprotkb:YP_0725(locus name)|uniprotkb:y0976(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852692|imex:IM-13779-5701	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"refseq:NP_001008697.1|refseq:NP_036275.1|refseq:XP_011528381.1|ensembl:ENSG00000100109.17(gene)|ensembl:ENST00000405938.5(transcript)|ensembl:ENST00000407148.5(transcript)|ensembl:ENST00000407431.5(transcript)|ensembl:ENST00000407690.6(transcript)|ensembl:ENST00000619735.4(transcript)|go:""GO:0000390""(spliceosomal complex disassembly)|go:""GO:0000398""(mRNA splicing, via spliceosome)|go:""GO:0000781""(chromosome, telomeric region)|go:""GO:0003676""(nucleic acid binding)|go:""GO:0005654""(nucleoplasm)|go:""GO:0005681""(spliceosomal complex)|go:""GO:0005730""(nucleolus)|go:""GO:0005737""(cytoplasm)|go:""GO:0006396""(RNA processing)|go:""GO:0016607""(nuclear speck)|go:""GO:0031012""(extracellular matrix)|go:""GO:0031214""(biomineral tissue development)|go:""GO:0031333""(negative regulation of protein-containing complex assembly)|go:""GO:0031848""(protection from non-homologous end joining at telomere)|go:""GO:0071008""(U2-type post-mRNA release spliceosomal complex)|go:""GO:0071013""(catalytic step 2 spliceosome)|go:""GO:2001033""(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|interpro:IPR045211|mint:Q9UBB9|rcsb pdb:8RO2|reactome:R-HSA-72163|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1|panther:PTHR23329(orthology-group)"	"interpro:IPR027417|interpro:IPR038729|uniprotkb:A0A6B3T1W4(uniprot-removed-ac)|go:""GO:0004527""(exonuclease activity)|go:""GO:0006302""(double-strand break repair)|go:""GO:0016887""(ATP hydrolysis activity)|refseq:WP_002223265.1"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2024/11/14	rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606	rogid:kLIIS2zCAycudIvZsl7pSdsTqz0632	intact-crc:538C8FC7C66171BF|rigid:vdNNRULNbS2B+qevW6o5D0p4e5E	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q9NQB0	uniprotkb:Q8ZJP7	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274.4	intact:EBI-2842065|uniprotkb:Q0WKP7	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:pyre_yerpe(display_long)|uniprotkb:pyrE(gene name)|psi-mi:pyrE(display_short)|uniprotkb:YPO0045(locus name)|uniprotkb:y0096(locus name)|uniprotkb:YP_0046(locus name)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:632(yerpe)|taxid:632(Yersinia pestis)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852720|imex:IM-13779-5705	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"ensembl:ENSG00000148737.18(gene)|ensembl:ENST00000355995.9(transcript)|go:""GO:0000122""(negative regulation of transcription by RNA polymerase II)|go:""GO:0000785""(chromatin)|go:""GO:0000976""(transcription cis-regulatory region binding)|go:""GO:0000978""(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:""GO:0000981""(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:""GO:0001568""(blood vessel development)|go:""GO:0003700""(DNA-binding transcription factor activity)|go:""GO:0005634""(nucleus)|go:""GO:0005654""(nucleoplasm)|go:""GO:0006357""(regulation of transcription by RNA polymerase II)|go:""GO:0008013""(beta-catenin binding)|go:""GO:0009749""(response to glucose)|go:""GO:0010718""(positive regulation of epithelial to mesenchymal transition)|go:""GO:0010909""(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:""GO:0016605""(PML body)|go:""GO:0016922""(nuclear receptor binding)|go:""GO:0019901""(protein kinase binding)|go:""GO:0031016""(pancreas development)|go:""GO:0032024""(positive regulation of insulin secretion)|go:""GO:0032092""(positive regulation of protein binding)|go:""GO:0032350""(regulation of hormone metabolic process)|go:""GO:0032993""(protein-DNA complex)|go:""GO:0042593""(glucose homeostasis)|go:""GO:0043433""(negative regulation of DNA-binding transcription factor activity)|go:""GO:0043565""(sequence-specific DNA binding)|go:""GO:0043570""(maintenance of DNA repeat elements)|go:""GO:0045295""(gamma-catenin binding)|go:""GO:0045444""(fat cell differentiation)|go:""GO:0045721""(negative regulation of gluconeogenesis)|go:""GO:0045892""(negative regulation of DNA-templated transcription)|go:""GO:0045944""(positive regulation of transcription by RNA polymerase II)|go:""GO:0048625""(myoblast fate commitment)|go:""GO:0048660""(regulation of smooth muscle cell proliferation)|go:""GO:0050679""(positive regulation of epithelial cell proliferation)|go:""GO:0051897""(positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction)|go:""GO:0060070""(canonical Wnt signaling pathway)|go:""GO:0061629""(RNA polymerase II-specific DNA-binding transcription factor binding)|go:""GO:0070016""(armadillo repeat domain binding)|go:""GO:0070369""(beta-catenin-TCF7L2 complex)|go:""GO:0071664""(catenin-TCF7L2 complex)|go:""GO:0090090""(negative regulation of canonical Wnt signaling pathway)|go:""GO:1900182""(positive regulation of protein localization to nucleus)|go:""GO:1990841""(promoter-specific chromatin binding)|go:""GO:1990907""(beta-catenin-TCF complex)|go:""GO:2000675""(negative regulation of type B pancreatic cell apoptotic process)|go:""GO:2001237""(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430|reactome:R-HSA-9823730|reactome:R-HSA-9825892|refseq:NP_001139746.1|refseq:NP_001139755.1|refseq:NP_001139756.1|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270141.1|refseq:XP_005270146.1|refseq:XP_005270153.1|refseq:XP_005270160.1|refseq:XP_016872081.1|refseq:XP_016872082.1|efo:""Orphanet:528084""|dip:DIP-36236N|ensembl:ENST00000352065.10|ensembl:ENSP00000344823.5|ensembl:ENST00000355717.9|ensembl:ENSP00000347949.4|ensembl:ENSP00000348274.4|ensembl:ENST00000369397.8|ensembl:ENSP00000358404.4|ensembl:ENST00000538897.5|ensembl:ENSP00000446172.1|ensembl:ENST00000627217.3|ensembl:ENSP00000486891.1|panther:PTHR10373(orthology-group)"	"interpro:IPR004467(Orotate phosphoribosyl transferase)|interpro:IPR023031|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|go:""GO:0000287""(magnesium ion binding)|go:""GO:0004588""(orotate phosphoribosyltransferase activity)|go:""GO:0005737""(cytoplasm)|go:""GO:0006207""('de novo' pyrimidine nucleobase biosynthetic process)|go:""GO:0006221""(pyrimidine nucleotide biosynthetic process)|go:""GO:0044205""('de novo' UMP biosynthetic process)|go:""GO:0046132""(pyrimidine ribonucleoside biosynthetic process)|refseq:WP_002208996.1|refseq:YP_002345141.1|panther:PTHR46683(orthology-group)"	"psi-mi:""MI:0469""(intact)"	-	-	figure legend:Table S2|curation depth:imex curation|full coverage:Only protein-protein interactions	"taxid:4932(yeasx)|taxid:4932(""Saccharomyces cerevisiae (Baker's yeast)"")"	-	2010/06/17	2025/02/10	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:koDayvC3+WfBy8Jsnu0tOjHIjEw632	intact-crc:154024A63256BA56|rigid:+Q2B1UyYIJbZ2zqrAA2GXNbomaI	false	-	-	-	-	"psi-mi:""MI:0078""(nucleotide sequence identification)"	"psi-mi:""MI:0078""(nucleotide sequence identification)"
uniprotkb:Q0WDR2	uniprotkb:Q12789	intact:EBI-2846656|uniprotkb:Q74W15|uniprotkb:Q8D123	intact:EBI-357956|uniprotkb:B2RP21|uniprotkb:Q12838|uniprotkb:Q6DKN9|ensembl:ENSP00000348510.4|uniprotkb:Q9Y4W9	"psi-mi:miab_yerpe(display_long)|uniprotkb:miaB(gene name)|psi-mi:miaB(display_short)|uniprotkb:""tRNA-i(6)A37 methylthiotransferase""(gene name synonym)|uniprotkb:YPO2620(locus name)|uniprotkb:y1195(locus name)|uniprotkb:YP_1093(locus name)|uniprotkb:""(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB""(gene name synonym)"	psi-mi:tf3c1_human(display_long)|uniprotkb:GTF3C1(gene name)|psi-mi:GTF3C1(display_short)|uniprotkb:Transcription factor IIIC subunit alpha(gene name synonym)|uniprotkb:TF3C-alpha(gene name synonym)|uniprotkb:Transcription factor IIIC 220 kDa subunit(gene name synonym)|uniprotkb:TFIIIC box B-binding subunit(gene name synonym)	"psi-mi:""MI:0398""(two hybrid pooling approach)"	Dyer et al. (2010)	imex:IM-13779|pubmed:20711500	taxid:632(yerpe)|taxid:632(Yersinia pestis)	taxid:9606(human)|taxid:9606(Homo sapiens)	"psi-mi:""MI:0915""(physical association)"	"psi-mi:""MI:0469""(IntAct)"	intact:EBI-2852734|imex:IM-13779-5709	author score:1|intact-miscore:0.37	-	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0499""(unspecified role)"	"psi-mi:""MI:0496""(bait)"	"psi-mi:""MI:0498""(prey)"	"psi-mi:""MI:0326""(protein)"	"psi-mi:""MI:0326""(protein)"	"interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR020612|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR006463(""tRNA-i(6)A37 modification enzyme MiaB"")|interpro:IPR007197(Radical SAM)|interpro:IPR023404|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|refseq:WP_002227875.1|go:""GO:0005829""(cytosol)|go:""GO:0035597""(""tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity"")|go:""GO:0035600""(tRNA methylthiolation)|go:""GO:0046872""(metal ion binding)|go:""GO:0051539""(4 iron, 4 sulfur cluster binding)|interpro:IPR038135|refseq:YP_002347576.1|panther:PTHR43020(orthology-group)"	"ensembl:ENSG00000077235.18(gene)|ensembl:ENST00000356